bluuebunny/crossref_metadata_2025 huggingface dataset:
ДИНАМИКА ПОКАЗАТЕЛЕЙ ПАМЯТИ И УСТОЙЧИВОСТИ ВНИМАНИЯ У ЛИЦ, ПЕРЕНЕСШИХ COVID-19
Authors: И.К. Жумабекова , В.Б. Молотов-Лучанский , Л.Л. Мациевская
Published: November 2024

оценить значение эквивалентного показателя памяти по шкале Векслера, а также интегрального показателя устойчивости внимания по корректурной пробе Бурдона у пациентов, перенесших коронавирусную инфекцию Материалы и методы: За февраль 2021 — апрель 2022 года было обследовано 84 пациента, проходящих реабилитационное лечение в лечебно-профилактических учреждениях г. Караганды. Возраст обследуемых составил от 24 до 77 лет. Пациенты были распределены по 3 группам, в зависимости от давности COVID-19. В ходе проспективного исследования для изучения состояния памяти и устойчивости внимания были применены шкала памяти Векслера и корректурная проба Бурдона (показатели тестов) на разных периодах после перенесённой коронавирусной инфекции. Статистическая обработка данных проводилась с помощью программ IBM SPSS Statistics, версия 27 и Statistica 10. Результаты. В статье представлены результаты проведенного исследования, в котором изучены состояние памяти и устойчивость внимания на разных временных промежутках после перенесённого COVID-19. В результате проведенного исследования выявлены средне групповые показатели со снижением памяти и уровня внимания сразу после перенесенного COVID-19. Кроме того, отмечена тенденция к улучшению показателей памяти и устойчивости внимания через 3-6 месяцев после перенесенного COVID-19 с 87 до 89 и с 5,5 до 10 единиц соответственно, p <0,05. Кроме того, выявлено повышение данных показателей в периоде 6-12 месяцев после перенесенной коронавирусной инфекции: эквивалентного показателя памяти до 93, а устойчивости внимания до 13 (p = 0,0093). Также выявлена взаимосвязь показателей памяти, устойчивости внимания и периода после перенесенного COVID-19 (r=0,32 и r=0,80 соответственно, p<0,05). Выводы: показатели памяти и внимания зависят от времени после перенесенного COVID-19.
МЫСТЫҢ АҒЗАҒА ЖӘНЕ БАУЫРҒА УЫТТЫ ӘСЕРІН СОРБЕНТТЕРМЕН ТӨМЕНДЕТУГЕ АРНАЛҒАН ӘДЕБИ ШОЛУ
Authors: Х.Р. Абдикадирова , К.Е. Амреева , К.Э. Мхитарян , Н.К. Омарбекова
Published: November 2024

Мақалада өндіріс, өнеркәсіп орындары мен басқада көздерден шығатын шаң құрамымен бірге түсетін ауыр және түсті металл тұздары – кәсіптік және қоршаған ортаны ластап қана қоймай, адам ағзасына зиянды және кеселді салдары бар туралы жазылған. Көптеген ғалымдардың зерттеулерінде, улы ауыр металл тұздары әсер еткенде пектинді сорбент ретінде тәжірибе жүзінде қолданып, нәтижесінде тимділігі төмен көрсеткішке ие болған. Себебі пектин сумен белсенді әрекеттесетін сорбент болғандықтан, суда еритін уларды шығаруға ғана қабілетті. Демек ішекте улармен байланысқа түсетін және ішектегі улардың қайта сіңірілуіне кедергі жасайтын, олардың ағзадан шығарылуына ықпал ететін әртүрлі энтеросорбенттерді қолдану тиімді. Бұл мәселені шешудің жолының бірі, металдарды асқазан – ішек жолдары арқылы шығару үдерісін пайдалану. Металдардың реобсорбциясы тоқтатылған жағдайда, олардың ішек арқылы шығарылу тиімділігі арта түседі. Бұл үшін ішектегі улы заттар мен бірқатар метаболиттерді сорбциялау үдерісі қолданылатыны белгілі. Соның нәтижесінде этиологиясы әртүрлі патологиялық үдерістердің ағымы тиімді бағытта реттеледі және улы заттар да сыртқа шығарылады. Зерттеу мақсаты: сорбциялық заттарды қолдана отырып мыстың ағзаға және бауырға уытты әсерін төмендетуге арналған әдебиеттерге талдау жасау. Материалдар мен әдістер: Ақпаратты талдап, салыстып ғылыми деректердің негізгі сипаттамалары анықталды. Жинақтаған эксперименттік деректеріміз арнаулы тағамның профилактикалық және антигепатоуыттық қасиетке ие, өйткені құрамы антиоксиданттық әсерге бай алмастырылмайтын аминоқышқылдар мен май қышқылдарынан, тағамдық талшықтардан, витаминдерден, минаралдық заттардан тұрады. Осылайша, полиметалл шаңының құрамындағы мыстың жалпы ағзаға және бауырға гепатоуытты әсерін азайтуға бағытталған әдеби ғылыми дереккөздерден алынған мәліметтер алуан түрлі. Сондықтан, ағзадан уытты заттарды шығарудың тиімді тәсілі алмиентарлық коррекцияны қолдану.
ВЗАИМОСВЯЗЬ ЭТИОЛОГИЧЕСКОГО АГЕНТА И ТЕЧЕНИЯ ТЯЖЕЛЫХ ОСТРЫХ РЕСПИРАТОРНЫХ ИНФЕКЦИЙ У ДЕТЕЙ С ОТЯГОЩЕННЫМ ПРЕМОРБИДНЫМ ФОНОМ
Authors: Г.О. Есимханова , Д.А. Баешева , Г.Д. Жумагалиева , Б.Р. Турдалина , А.Ш. Каипова , А.Ж. Сейдуллаева , А.Е. Отарбаева
Published: November 2024

В данной статье изучены особенности клинического течения тяжелых острых респираторных инфекций у детей с преморбидным фоном в зависимости от этиологического агента. Проведен ретро- и проспективный анализ клинического течения 681 пациента с тяжелой острой респираторной инфекцией (ТОРИ), госпитализированных в ГКП на ПХВ «Многопрофильная городская детская больница №3» г. Астана. Изучены клинико-лабораторные проявления у 411 детей с этиологически расшифрованными ТОРИ. Этиологическую верификацию возбудителей гриппа и ОРВИ проводили методом ПЦР. Определена частота встречаемости различных возбудителей тяжелого течения гриппа и ОРВИ у детей с преморбидным фоном. ТОРИ регистрировалась часто в 2,3 раза у младенцев первого года жизни с отягощенным преморбидным фоном с негладким течением с развитием осложнений в ранние периоды заболевания: в 85,7% до 98,4% случаев. При гриппе в основной группе детей пневмония как осложнение отмечалась в 1,7 раз чаще в сравнении с группой контроля, бронхообструктивный синдром в 3 раза выше. При этом среднее значение сатурации у больных составило 92 в основной группе, что было достоверно статистически значимо в сравнении с группой без фоновой патологии (р <0.001). В группе ОРВИ негриппозной этиологии пациенты поступали с пневмонией в 40,1% случаев с явлениями гипоксемии, дыхательная недостаточность за счет развития БОС развивалась в 38% случаев. В данной работе выявлена взаимосвязь факторов преморбидного фона на течение и исход ТОРИ в зависимости от инфекционного агента.
Research Centers: Between the Logic of Thought and the Logic of Action
Authors: Mohammed Dr. Benazzouzi
Published: November 2024

This paper aims to analyze the foundational elements that must precede the success of scientific work framed within scientific institutions commonly referred to as research centers. These centers have become essential in modern times due to their contributions to both scientific and social movements and their impact on public policies of states. They function as research laboratories addressing analysis and investigation processes to establish a predictive framework for the future, not only of the social environment but also of the global context in its intellectual and cultural manifestations. Therefore, these emerging institutions are expected to act as safeguards against negative influences on the identity aspects of society by preserving, inspiring, and reviving heritage in ways that allow it to provide qualitative contributions to the present. Today’s reality faces challenges of cultural and existential uniformity, driven by globalization, which seeks to standardize the world through a reductive vision imposing its demagoguery worldwide.
PREDICTIVE FACTORS AND LEVELS OF AMPUTATION IN PATIENTS WITH DIABETIC FOOT ULCER
Authors: Naeem Dr. Spogmay , Ali Dr Irum Sabir , Fatima Dr. , Nazish Dr. , Ali Dr. Rabia
Published: November 2024

Diabetes mellitus complicated by diabetic foot ulcer leading to amputation carries socio-financial implications. The spectrum of the issue extends globally. Knowledge of burden of factors leading to amputations at various level is vital in understanding the gravity of the problem. Objective: To determine the frequency of predictive factors and levels of amputation in patients with diabetic foot ulcer. Materials and methods: This cross sectional study was carried out at department of surgery, Khyber Teaching Hospital, during the period 13th June 2022 till 12th December 2022. A total of 180 male and female patients in the age range 30 to 60 years undergoing amputation for diabetic foot ulcer were enrolled. Predictive factors and level of amputation were noted. Data was analyzed using SPSS version 25. RESULTS: Mean age of the patients was 46.68 ± 10.239 years. The number of female participants was 101 (56.1%). Most common predictive factor observed was peripheral arterial disease in 75 (41.7%) patients while below knee amputation was most common procedure performed in 85 (47.2%) patients. CONCLUSION: Female patients with grade 3 and above Wagner diabetic foot with peripheral arterial disease were more likely having lower limb amputation. Amputation below knee was most common.
The role of pharmacogenomics in personalized nursing care: Laboratory techniques and clinical applications
Authors: Alanazi Ali Jamal , Almutairi Nawal Hayef Bejad , Alakroosh Abdulkhaliq Abdullh , Alyamani Ibrahim Mohammed , Alotibi Fares Saad N
Published: November 2024

Background: Pharmacogenomics (PGx), the study of genetic variations affecting drug response, is a cornerstone of personalized medicine. It holds immense potential in nursing care by enabling tailored treatment strategies, enhancing therapeutic efficacy, and minimizing adverse drug reactions (ADRs). Despite its promise, PGx integration into clinical nursing practice faces challenges such as high costs, limited access to testing, and a knowledge gap among healthcare professionals. Aim: This paper aims to examine the role of pharmacogenomics in advancing personalized nursing care. It focuses on identifying key genetic markers influencing drug response, exploring laboratory techniques employed in PGx testing, and highlighting clinical applications that inform nursing practice. Methods: The study undertakes a systematic literature review from databases like PubMed and Google Scholar, emphasizing pharmacogenetic markers, laboratory methodologies, and nursing applications. Laboratory techniques such as next-generation sequencing (NGS) and genotyping are analyzed, alongside clinical case studies to demonstrate the real-world impact of PGx on nursing interventions. Results: Pharmacogenomics significantly improves nursing care by guiding drug selection and dosages through genetic insights. Laboratory techniques identify key markers such as CYP450 polymorphisms, optimizing medication safety and efficacy. Clinical applications show reduced ADRs, improved adherence, and better patient outcomes.
Bridging gaps between pharmacy, nursing, and laboratory sciences: A multidisciplinary approach
Authors: Alreshidi Mohammad Saud , Alharbi Saleh Helayyil Saleh , Alotaibi Naif Munif Aldumayki
Published: November 2024

Background: To improve patient outcomes, pharmacy, nursing, and laboratory sciences must work together seamlessly due to the complexity of modern healthcare. However, the potential of integrated care is hampered by ongoing deficiencies in multidisciplinary education, operational procedures, and communication. A multidisciplinary strategy that unifies the knowledge of several disciplines is needed to address these issues and create a holistic healthcare model. Aim: This paper aims to explore the intersections between pharmacy, nursing, and laboratory sciences, identify systemic gaps that impede collaboration, and propose strategies to foster effective interdisciplinary integration. Methods: A thorough study of the literature was done with an emphasis on interdisciplinary approaches in healthcare systems around the world. In order to find effective integration models, key case studies were examined. Qualitative insights were obtained through surveys and interviews with pharmacy, nursing, and laboratory science practitioners. To measure the advantages of collaboration, patient outcomes in integrated vs siloed healthcare systems were compared. Results: The results point to several important obstacles, such as compartmentalized operations, mismatched communication channels, and a lack of interdisciplinary training.
Doctor Honoris Causa Luis García Montero
Authors: García Montero Luis
Published: November 2024

El grado de Doctor Honoris Causa es la distinción académica más importante que otorga la Universidad de Colima, y se entrega a quienes han contribuido de manera decisiva al desarrollo de las ciencias, las artes y las humanidades. Este libro es un testimonio de la memorable visita de Luis García Montero a la Universidad de Colima, e incluye una brevísima pero significativa selección de su poesía. En conjunto, la presente obra expresa la convicción poética de García Montero por construir un mundo libre y pleno desde las universidades, que él mismo definió como los espacios culturales para la reflexión humana, la gestación del conocimiento y la absoluta libertad de aprendizaje. En la Universidad de Colima suscribimos ese compromiso con las humanidades y la educación para la transformación positiva de la realidad.
Versos a mordidas
Authors: Sánchez Cristina Yunuén , Rivas Rios Evelyn Anayelzin
Published: November 2024

Versos a mordidas es una jicarada fresca de experimentación con la palabra y las emociones. En el agua que se vierte, y que nos baña de pies a cabeza, confluyen la sensualidad y el erotismo, el dolor de la distancia, la incertidumbre y el amor, entre un sinfín de tonalidades que deja la condición humana puesta al desnudo en este balcón juvenil del universo poético.
Perspectivas metodológicas para los estudios de género
Authors: Martínez Guzmán Antar , Cruz Manjarréz Adriana , Cuevas Hernández Ana Josefina
Published: November 2024

Los estudios de género y el pensamiento feminista han sido campos fértiles de trabajo intelectual y académico; durante las últimas décadas han generado herramientas teóricas para abordar problemáticas relacionadas con la igualdad de género en nuestras sociedades, pero también han generado cuestionamientos y replanteamientos el ámbito de la producción de conocimiento a nivel epistemológico y metodológico en las ciencias sociales. En este artículo damos cuenta de la forma en que la mirada de género ha transformado y definido el proceso de investigación y el quehacer metodológico en tres diferentes disciplinas–antropología, sociología y psicología social-, a través del itinerario de las autoras en el estudio de diferentes problemáticas sociales relacionadas con el género. A través de estos itinerarios mostramos la manera en que hemos incorporado miradas y herramientas de la perspectiva de género para la construcción nuestros marcos epistémicos y metodológicos en función de diferentes objetos de investigación: la perspectiva etnográfica en torno a la migración indígena femenina (Autora 2); un enfoque sociológico cualitativo que utiliza herramientas como la entrevista, la etnografía y la historia oral en torno al estudio de las familias y las emociones (Autora 3); y un enfoque de investigación psicosocial de tipo narrativo en torno a la construcción de identidades trans y la formación de masculinidades violentas (Autora 1). Posteriormente, ponemos en diálogo estos diferentes itinerarios identificando aspectos comunes y singularidades, así como desafíos inter y transdisciplinares para la investigación en género desde las ciencias sociales. El objetivo de este intercambio es contribuir a enriquecer los itinerarios con que es posible incorporar al género, no sólo como un campo temático, sino también como un enfoque metodológico en el estudio de problemáticas vigentes en nuestras sociedades.
Elementos para la crítica de la cultura nacional
Authors: Garduño Comparán Carlos Alfonso
Published: November 2024

En este texto se discuten los principios para la crítica de la noción de cultura nacional y discernir la dialéctica de su identidad político-cultural, desde una perspectiva filosófica orientada por las inconsistencias de la relación entre los Estados-nación y la dinámica de mercado a nivel global, más que por la interpretación del sentido de tradiciones culturales e identificaciones étnicas o por las pretensiones liberales de un sistema integrador de la diversidad cultural. Para ello, se partirá del diagnóstico de Hannah Arendt de los dos principales síntomas del imperialismo como correlato de la consolidación del Estado-nación: el racismo y las personas sin-Estado. A partir de ello, se discutirá desde una perspectiva decolonial apoyada en Frantz Fanon, Tzvetan Todorov y Houria Bouteldja la posibilidad de una acción política emancipadora por quienes son excluidos de la nación. Finalmente, a través de Giorgio Agamben, Judith Butler, Alain Badiou y Slavoj Žižek se discutirá la identidad político-cultural del sujeto que pretende superar las inconsistencias del nacionalismo, considerando la performatividad de su intervención del espacio público, la naturaleza de los acontecimientos políticos que genera y la crítica de la ideología requerida para precisar el sentido dialéctico de sus estrategias.
Imagen del árabe/musulmán en el imaginario colectivo occidental
Authors: MSAHAL Youssef
Published: November 2024

La conceptualización de una imagen deformada en torno al árabe/musulmán es resultado de un proceso enmarañado donde la relación entre el Nosotros occidental y el Otro oriental reviste un carácter hostil y devastador. La dominación del Otro diferente es el cúmulo complicado de procesos históricos donde se entrecruzan las teorías filosóficas y científicas con las recomendaciones religiosas de los misioneros al servicio de la era colonial. El trasfondo histórico basado en las colonizaciones ha cimentado sólidas plataformas para fijar en la memoria colectica occidental una diferencia constante entre el occidental superior frente al otro inferior. Estas bases se alimentan, hoy en día, en nuevas vertientes para seguir marcando brechas entre ambas partes, y fosilizar, con mucha fluidez, en la idiosincrasia del occidental la imagen del otro bárbaro e impotente.
En este ensayo, hemos elaborado un breve recorrido diacrónico acerca de la relación entre Occidente y Oriente para exponer algunas teorías pertenecientes a distintos campos, y que han sido aprovechadas para justificar el proceso colonial. Asimismo, hemos intentado delimitar las nuevas vertientes que avivan la estereotipia inherente al árabe/musulmán y que concretizan la inferioridad del otro oriental, a saber: los medios de comunicación, la industria cinematográfica, la novelística y las traducciones.
Forcejeando con los ángeles
Authors: Del Monte Madrigal Juan Antonio
Published: November 2024

El libro Forcejeando con los ángeles. Introducción interesada a Stuart Hall es en palabras de su autor, Eduardo Restrepo, una invitación a leer a Stuart Hall. No es un convite menor en tanto nos encontramos ante la gran oportunidad de tener sistematizado y ordenado el pensamiento de Stuart Hall para un público en español. Según lo cuenta en las primeras páginas, el libro es producto de una larga y paciente revisión que duró años, que pasó por una serie de seminarios y cursos y cuyo corolario ahora tiene el inusitado título de Forcejeando con los ángeles.
Sosialisasi NIB dan Sertifikasi Halal guna memperluas pasar Kuliner UMKM Desa Sraten
Authors: Jufri Lorenza , Syafa'at Arman , Amrizal Amrizal
Published: November 2024

Usaha Mikro, Kecil, dan Menengah (UMKM) yang ada di Desa Sraten masiih banyak yang belum mengetahui perihal apa itu legalitas dan pentingnnya legalitas untuk sebuah usaha. Kegiatan ini saya lakukan dengan tujuan membantu para pelaku UMKM yang ada di Desa Sraten untuk lebih memahami lagi terkait legalitas usaha, seperti Nomor Izin Berusaha (NIB) dan Sertifikasi Halal. Oleh karena itu saya disini membuat kegiatan berupa sosialisasi dan pendampingan kepada para pelaku UMKM mengenai NIB dan Sertifikasi Halal terkhusus di bidang kuliner, sebelum mengadakan sosialisasi saya melakukan observasi di Desa Sraten terlebih dahulu. Dan setelah melakukan observasi selama 7hari saya berhasil mendampingi 28 pelaku UMKM di Desa Sraten untuk didaftarkan dan memperoleh NIB. Sementara untuk Sertifikasi Halal kami hanya fokus melakukan seminar saja dengan mengikut sertakan Ibu Ambarwati yang akan mendampigi lebih lanjut mengenai pendaftaran Sertifikasi Halal nantinya. Kegiatan ini saya akhiri dengan acara seminar lebih lanjut mengenai NIB dan Sertifikasi Halal yang dihadiri dengan para narasumber khusus untuk memperdalam pengetahuan para pelaku UMKM tentang legalitas dan Sertifikasi Halal.
Research Progress on Concurrent Surgical Approaches in the Treatment of Benign Prostatic Hyperplasia (BPH)
Authors: Liu Xijun , Zeng Xiangyang
Published: November 2024

Benign prostatic hyperplasia (BPH) is an age-related non-cancerous condition, affecting approximately 50% of men over the age of 50, with the prevalence rising to over 80% in men over 80 years old. Elevated prostate-specific antigen (PSA) levels are commonly indicative of prostate diseases such as BPH or prostate cancer. In patients with multiple comorbidities and a limited life expectancy, even if prostate cancer is diagnosed, they may not be candidates for radical surgery. Therefore, a treatment approach that can both diagnose and relieve lower urinary tract obstruction is needed. Performing prostate biopsy and surgical treatment concurrently allows for both diagnosis and therapy in a single procedure, reducing the risks and recovery time associated with multiple surgeries, while enhancing the patient’s treatment experience and satisfaction. This article aims to explore the efficacy and safety of concurrent prostate biopsy and 1470 nm laser surgery.
Exploring the Teaching of Curriculum Politics in Biomass Conversion Principles and Technology Based on the New Engineering Background
Authors: Peng Jinxing
Published: November 2024

Curriculum ideological and political education is a new concept and model of curriculum teaching of various majors to adapt to the development of the new era and the new international and domestic situation. Under the background of "new engineering", integrating the curriculum thought and politics into each link of the teaching of biomass energy conversion principle and technology, and exploring the best "fusion point" is a direction worthy of in-depth research in teaching. In the teaching practice of biomass energy transformation principle and technology course, teachers should fully reflect the unique humanistic temperament of biomass energy transformation principle and technology course, and explore the ideological and political education content of socialist core values, which can not only promote students to improve their professional ability, but also improve their thoughts and behaviors. This paper mainly puts forward the integration point of biomass energy transformation principle and technology and ideological and political education, as well as the strategy of curriculum teaching improvement under the background of new engineering.
Construction and Exploration of Integrating Ideological and Political Education into The Course of “Tolerance and Measurement Technology”
Authors: Pan Shuwei
Published: November 2024

The course of “Tolerance and Measurement Technology” is a compulsory basic course for mechanical majors. Combining the characteristics of the course and the job requirements of product testing, the knowledge and ideological elements of the course are explored to optimize the teaching design.
INCIDENCE AND ASSOCIATION OF SERUM HYPOMAGNESEMIA WITH FEBRILE SEIZURES IN YOUNG CHILDREN
Authors: AKRAM MH , KHURSHID A , MAZHAR H
Published: November 2024

Febrile seizures (FS) are a common occurrence in pediatric patients, affecting 2-5% of children between 6 months and 5 years of age. Various factors have been implicated in the pathogenesis of febrile seizures, including electrolyte imbalances such as hypomagnesemia, which can influence neuronal excitability and seizure susceptibility. Objective: The study aimed to assess the incidence of serum hypomagnesemia in children with febrile seizures and to examine the association between hypomagnesemia and the occurrence of febrile seizures. Methods: This retrospective case-control study was conducted at the Emergency Department of Shifa International Hospital from September 2023 to August 2024. A total of 300 children aged 6 months to 5 years were included in the study. Of these, 150 children presented with febrile seizures (case group), while 150 febrile children without seizures (control group) were selected as the comparison group. Patient data, including gender, body temperature, birth weight, age of onset, history of febrile seizures, gestational age, family history of seizures, and serum magnesium levels, were recorded. Serum magnesium levels were measured within 12 hours of a seizure episode, and results outside the reference range of 0.85-1.15 mmol/L were considered abnormal. Statistical analysis was performed using SPSS, and a Pearson correlation test was conducted to assess the association between serum magnesium levels and febrile seizures. Results: The mean serum magnesium level was significantly higher in the control group (0.99 ± 0.0957 mmol/L) than in the case group (0.95 ± 0.133 mmol/L) (p < 0.01). Hypomagnesemia was observed in 42 (28%) of the children with febrile seizures compared to 15 (10%) of the control group. A negative correlation was found between serum magnesium levels and the occurrence of febrile seizures (Pearson’s coefficient = -0.1709), indicating that lower magnesium levels were associated with a higher likelihood of febrile seizures. Conclusion: Children with febrile seizures exhibit significantly lower serum magnesium levels compared to febrile children without seizures. Hypomagnesemia appears to be associated with an increased risk of febrile seizures, particularly in those with a personal or family history of febrile seizures. Early identification and correction of hypomagnesemia in children presenting with fever may help in preventing febrile seizures.
EFFECTIVENESS OF PRE-OPERATIVE NURSING INTERVENTION PROGRAM ON ANXIETY AND PERCEIVED CONTROL PROGRAM IN PATIENT UNDERGOING CARDIAC SURGERY
Authors: YASIN M , ARSHAD M , NIGAR Z , TASNEEM SS , JABEEN R
Published: November 2024

Patients undergoing cardiac surgery often experience significant preoperative anxiety, which can adversely affect surgical outcomes and recovery. Enhancing perceived control through structured nursing interventions has shown potential in alleviating anxiety and improving patient outcomes. However, evidence on the effectiveness of such interventions in resource-limited settings, such as Pakistan, is limited. Objective: To evaluate the effectiveness of a preoperative nursing intervention program in reducing anxiety and enhancing perceived control among patients undergoing cardiac surgery. Methods: This randomized controlled trial included 56 adult patients scheduled for cardiac surgery at Social Security Hospital, Lahore. Participants were randomly assigned to either an intervention group, receiving a structured nursing program, or a control group, receiving standard care. The intervention included educational sessions, relaxation techniques, and personalized consultations. Anxiety and perceived control were measured pre- and post-intervention using the State-Trait Anxiety Inventory (STAI) and a validated perceived control scale. Statistical analyses were conducted using paired and independent t-tests. Results: The intervention group demonstrated a significant reduction in mean anxiety scores (from 47.2 to 38.3, p < 0.001) and an improvement in mean perceived control scores (from 22.4 to 26.8, p < 0.01). Participant feedback indicated high satisfaction, with 78.6% expressing moderate to high approval of the program. Conclusion: The preoperative nursing intervention program effectively reduces anxiety and enhances perceived control in patients undergoing cardiac surgery. Integrating such interventions into standard care can improve psychological well-being and surgical outcomes, particularly in resource-limited healthcare settings. Further research is recommended to evaluate the long-term benefits and applicability of these interventions in diverse populations.
Association between Overhang of the Posterior Horn of Lateral Meniscus and ACL Injuries
Authors: Abed Noor Yousif , Huweidy Bashar Talib , Mohammed Rajaa Abdullah , Abed Maysam Yousif
Published: November 2024

Background: The anterior cruciate ligament (ACL) tear is one of the most common injuries among young athletes. Posterior displacement of the posterior horn of the lateral meniscus caused by anterior translation of the tibia has been recorded as a secondary finding of the anterior cruciate ligament (ACL) injury. Objective: to discriminate the association between the overhang of the posterior horn of the lateral meniscus and the anterior cruciate ligament tear. Methods: A specialist radiologist performed a comparative cross-sectional study at Al Ramadi Teaching Hospital, diagnosing 60 patients with ACL tears based on MRI findings, measuring the lateral meniscus overhang value, percentage meniscus diameter, and lateral tibial plateau diameter. Results: A significant difference between studied groups regarding the presence of LMO was higher in group 1 than in group 2, with a mean value of 1.85±0.74 mm for group 1 and 0.80±0.16 mm for group 2, which are also significantly different. The meniscal overhang percentage and the lateral meniscus diameter were higher in the ACL tears group than in other subjects; however, the lateral tibial plateau was significantly higher in the latter group. Conclusions: A significant association has been reported between the overhang of the posterior horn of the lateral meniscus and the anterior cruciate ligament tear; we recommend further studies to display the clinical value of this finding.
Human Epididymis Protein-4 and Carbohydrate Antigen-125 for Diagnosis of Endometrial Carcinoma
Authors: Saed Sarah Mahmood , Al-Wazzan Raida
Published: November 2024

Background: Endometrial carcinoma (EC) is a common genital tumor that frequently causes abnormal uterine bleeding (AUB). All gynecologists aimed to differentiate between malignant and benign causes of AUB using a noninvasive approach. Tumor markers like human epididymis protein-4 (HE4) and carbohydrate antigen-125 (CA125) were employed and assessed in this investigation. Objectives: To quantify HE4 and CA125 levels in AUB patients and assess their significance in distinguishing between benign and malignant endometrial tumors. Methods: This prospective observational case series analysis included 88 patients with AUB who were admitted for surgical surgery in Mosul hospitals between January 1st and September 30th, 2022. Preoperative blood samples were collected to assess HE4 and CA125 levels. After collecting histopathological results, the patients were separated into two groups: malignant (24) and benign (64) that were further divided into pre- and postmenopausal subgroups. The biomarker level was determined and statistically evaluated. Results: All 24 malignant cases, reported among postmenopausal patients, showed statistically significant differences. The mean HE4 level was higher in the postmenopausal than premenopausal benign group. The mean CA125 level was substantially greater in the malignant than in the postmenopausal benign groups. CA125 showed greater validity markers than HE4. There was no significant relationship between HE4 and CA125 concentrations. Conclusions: Measuring CA125 levels in postmenopausal patients with AUB may help differentiate EC in those with endometrial thickness greater than the threshold value.
The Evolution and Impact of Animal Vaccines: Advancements, Applications, and Future Directions
Authors: Huang Ziqing
Published: November 2024

Abstract. Animal vaccines play a significant role in preventing and controlling animal infectious diseases, ensuring public health, and promoting the economic development of the livestock industry. This paper reviews the historical development of animal vaccines and explores their role in public health, the livestock economy, and the prevention and control of zoonotic diseases. It details several common types of animal vaccines, including inactivated vaccines, live attenuated vaccines, subunit vaccines, and mRNA vaccines, describing their preparation methods, immune mechanisms, and advantages and disadvantages. Additionally, the paper outlines the current application status of vaccines for three major animal infectious diseases: swine fever, bovine tuberculosis, and avian influenza. It also analyzes the development trends of new vaccine technologies, such as genetic engineering vaccines, nanoparticle vaccines, and oral and spray vaccines. Despite significant advances in vaccine technology, challenges remain, such as pathogen variation, technical and economic barriers, and issues related to regulation and quality control. This paper aims to provide direction for future research, emphasizing the importance of continuous technological innovation and a globally unified regulatory system. The goal is to develop new vaccines with stronger immunogenicity, fewer side effects, and better adaptability to pathogen variations, thereby enhancing the application effectiveness of animal vaccines in public health and the livestock industry.
Cause disparities in coronary heart disease between genders
Authors: Shen Isabella
Published: November 2024

Abstract. Limited studies investigated the differences between the causes of coronary heart disease in men and women. While some focused on one gender or the other, minimal studies indeed examined the differences in the significance of each of the common risk factors present in both genders. Thus, this study intends to do just that. This study uses data from the Framingham Heart Study, a long-term cardiovascular cohort study of the residents of Framingham, Massachusetts. A variety of factors were considered in examining the risk of coronary heart disease, including gender, age, and previous medical history. Exploratory data analysis and regression analysis were used to reveal the differences between men and women in determining the risk of coronary heart disease. Through regression analysis, apparent differences between males and females arose. Significant factors for men included age, systolic blood pressure, total cholesterol, and glucose levels, and significant factors for women additionally included the number of cigarettes smoked per day as well as a previous history of hypertension. The Framingham Heart Study has demonstrated the distinctions between men and women when it comes to the risks of coronary heart disease, allowing physicians to gain a deeper understanding of the disease. However, it fails to be inclusive of all races and ethnicities as participants in the first cohort and many later cohorts of the study were all Caucasian. This study also calls for future studies to build off the Framingham Heart Studys shortcomings and provide data and standards suitable for everyone.
Research Progress Regarding the Mechanism of Acupuncture in the Treatment of Stroke on the Nervous System
Authors: Xu Guiqiang
Published: November 2024

Abstract. Stroke is one of the leading causes of disability and death worldwide. Acupuncture, as a traditional Chinese medicine, has received considerable attention recently for its use in stroke-related nervous system treatments. Acupuncture exerts therapeutic effects through multiple mechanisms, including stimulating and regulating related factors and signaling pathways to play anti-inflammatory, neuronal repair and protective effects; controlling glial cell polarization to promote self-repair after brain injury, etc. Acupuncture has been shown to markedly decrease the inflammatory response following a stroke, facilitate nerve regeneration and cell proliferation within the central nervous system, enhance cerebral blood flow in ischemic regions, diminish neuron apoptosis, and ultimately lead to improvements in neurological function and quality of life for stroke patients. Nevertheless, the precise neural mechanisms underlying acupuncture's effects on stroke remain incompletely elucidated, warranting further comprehensive investigation. This article reviews the research progress on the neural mechanisms of acupuncture in the treatment of stroke in recent years, with a view to providing scientific basis and reference for its clinical application.
Konjac Glucomannan: Properties, Preparation, and Health Effects
Authors: Feng Yihan
Published: November 2024

Abstract. Konjac glucomannan (KGM), a natural polymer derived from konjac, is noted for its unique physicochemical properties and its extensive application across various fields. In recent years, the rising demand for healthy diets and functional foods has highlighted KGMs positive effects on blood sugar control, weight loss, and immune regulation, making it a focal point in food science research. This paper aims to deeply explore the physicochemical properties of KGM through detailed analysis. In the study of preparation methods, multiple techniques for preparing KGM were investigated, and the impact of different preparation methods on the properties of the product was discussed. In terms of health effects, relevant studies and experiments have demonstrated KGMs beneficial roles in blood sugar control, gut health, and immune modulation. Summarizing the findings of this research and looking towards the future, it is concluded that KGM has broad application prospects, providing scientific evidence for the continued development of konjac products.
Neurotechnology in ADHD Diagnosis: A Research on Innovations and Applications
Authors: Chen Siying
Published: November 2024

Abstract. Attention Deficit Hyperactivity Disorder (ADHD) is characterized by persistent symptoms of hyperactivity, impulsivity, and inattention, presenting significant challenges in daily functioning. Diagnosing ADHD, particularly in adulthood, can be intricate due to symptom overlap with other disorders and the subjective nature of behavioral assessments. However, advancements in neuroimaging techniques have illuminated the neurological underpinnings of ADHD, offering a more objective approach to understanding and diagnosing this neurodevelopmental condition. Neuroimaging technologies such as Electroencephalography (EEG), Near-Infrared Spectroscopy (NIRS), and Functional Magnetic Resonance Imaging (fMRI) have been pivotal in mapping the brain's functional and structural anomalies associated with ADHD.This review synthesizes the application of neuroimaging in the diagnosis of ADHD, encompassing EEG, fMRI, and NIRS. It discusses the potential and limitations of these technologies in assessing brain function and structure alterations in individuals with ADHD and explores their prospects for clinical application. As we conclude and look ahead, the continuous progress in technology and research is set to make neuroimaging an increasingly vital component in the diagnosis and treatment of ADHD. It promises to deliver more personalized and precise therapeutic approaches for individuals affected by this disorder.
Pretrained-ResNet-based COVID-19 CT image classification
Authors: Sun Shihan
Published: November 2024

Abstract. The COVID-19 pandemic has significantly affected global public health and the economy. Clinically, compared to nucleic acid testing, CT imaging offers a more intuitive display of disease progression, particularly in cases where patients exhibit atypical symptoms or when nucleic acid test results are inconclusive. In such scenarios, CT imaging serves as a valuable supplementary diagnostic tool. However, the task of classifying COVID-19 CT images presents numerous challenges. Firstly, the imaging features associated with COVID-19 exhibit significant heterogeneity, often overlapping with those of other pulmonary diseases such as pneumonia or tuberculosis, which complicates the classification process. Additionally, CT images typically contain noise and artifacts that can interfere with The model's capability to accurately differentiate between various conditions. This paper proposes a ResNet-based method for the classification of COVID-19 CT images. Experimental results demonstrate that the ResNet-based approach offers significant advantages, delivering high accuracy and strong generalization capabilities in classifying images related to COVID-19.
Soft bioelectronic materials for brain computer interface
Authors: Tang Muyuan
Published: November 2024

Abstract. Traditional rigid electronic materials for brain-computer interface cannot work stably and will cause rejection reactions and inflammation of the brain. In response, scientists have tried new strategies to develop flexible bioelectronic materials that can stably recognize and control neural activity in the tissue interface environment to monitor and modulate brain function, and meet desired level of effect to provide safe treatment to neural and muscle diseases such as Hence, in this comprehensive review, the paramount significance of optimal electronic materials tailored for Brain-Computer Interface (BCI) applications is underscored. The virtues of biocompatible materials are highlighted, delving into their fabrication methodologies, distinctive material attributes, and deployment in secure therapeutic interventions for a spectrum of neurological disorders including paralysis, dementia, and depression. Current investigations in this domain are presented, outlining the pivotal evaluation criteria for these materials. Recent advancements are introduced and synthesized, considering the prevailing influential factors that shape the field's trajectory. Additionally, the review acknowledges lingering hurdles and outlines prospective avenues for future exploration, ensuring a holistic perspective. Ultimately, the entire discourse culminates in a synthesis that validates the substantial applicability and potential of soft bioelectronic materials within the realm of interfacing computer science with biology, heralding a promising future in neurotechnology.
Effectiveness of Augmented Reality Technology in Enhancing Primary School Students' Acquisition of Creative Reading Skills
Authors: AlAli Rommel Mahmoud , Al-Barakat Ali Ahmad
Published: November 2024

The current study aimed to investigate the effectiveness of augmented reality (AR)-based learning in enhancing creative reading skills among primary school students in English language learning environments, specifically in Syrian refugee schools in northern Jordan. The study employed an AR-based learning guide and a creative reading skills test, both validated for accuracy and reliability. The study conducted with two groups. One as the experimental group using AR and the other, as the control group following conventional methods. The results indicated that the group that took part in the experiment performed better, than the control group in creative reading skills based on average scores achieved by them compared to the control group’s performance. The statistical analysis confirmed that these differences were of significance which implies that Augmented Reality had an impact on enhancing creative reading skills. These results suggest that Augmented Reality can have an improvement on creative reading skills by offering students captivating and interactive materials that aid in improving their understanding and vocabulary. The study proposes the incorporation of Augmented Reality technology in education to enhance the learning process and encourage creativity, among students. However the research had some shortcomings such, as concentrating on schools for refugees in Jordan which could restrict how widely the results apply Also they used only a few evaluation tools and did not look into the lasting effects of AR It would be valuable, for upcoming studies to look into how AR affects various educational settings delve into its enduring impacts and consider what teachers and students think about incorporating AR in teaching The research highlights that even though there are constraints, in the studys findings regarding the potential of Augmented Reality (AR) to boost creative reading skillsand enhance educational achievements.
Влияние инсулинотерапии на взaимосвязь ферментов метаболизма L-аргинина в лейкоцитах и плазме крови придлительнoм сахарном диабете 1 типа
Authors: Алчуджян Н. Х. , Оганнисян М. Р. , Мовсесян Н. О. , А. А. А. А. , Айрапетян Р. Л. , Мелконян А. М. , Агаджанова Е. М.
Published: November 2024

Երկարատև տիպ 1 շաքարային դիաբետով տառապող դեռահասների և երիտասարդների շրջանառվող լեյկոցիտներում արգինազի և ազոտի օքսիդի սինթազի ակտիվության կոռելյացիան խախտվում է անկախ ինսուլինաթերապիայից: Միաժամանակ պլազմայում տղաների մոտ գրանցվել է թերապիայի դրական ազդեցությունը ֆերմենտների միջև կոռելյացիոն կապի վրա, իսկ աղջիկների մոտ՝ բացասական։ Լեյկոցիտներում և արյան պլազմայում արգինազի և ազոտի օքսիդի սինթազի փոխազդեցության սեռային տարբերությունները կարող են արտացոլել հիվանդի վիճակը և աուտոիմուն շաքարախտի բուժման ընթացքը:
In circulating leukocytes of adolescents and young Armenians with long-term type 1 diabetes mellitus, a correlation between the activities of arginase and nitric oxide synthase was significantly reduced despite treatment with insulin. At the same time a positive effect of insulin therapy on the correlation was found in the plasma of boys, a negative effect was found in the plasma of girls. Sex differences in the relationship between arginase and nitric oxide synthase in leukocytes and blood plasma may reflect the patient's condition and the course of therapy for autoimmune diabetes.
Knowledge, Attitude and Beliefs Regarding Varicella Infection and Immunization among Healthcare Workers in Armenia:A Cross-Sectional Survey, 2023
Authors: Manukyan A. H. , Grigoryan S. S. , Badalyan A. R. , Karapetyan L. G. , Mheryan G. V. , Ghukasyan, M. A. M. A. , Khachatryan N. P. , Sahakyan G. F.
Published: November 2024

Ветряная оспа – высококонтагиозное вирусное заболевание. В 2024 году Армения планирует включить вакцину против ветряной оспы в Национальный календарь иммунизации. Целью данного исследования было оценить знания, отношение и личные убеждения медицинских работников по поводу инфекции ветряной оспы и вакцинации, чтобы предоставить информацию об изменениях в календаре иммунизации Армении. Всего в опросе приняли участие 779 медработников. 96% опрошенных составили женщины в возрасте от 21 до 77 лет (средний возраст 53±11 лет). Средний балл знаний медсестер составил 6,7 по сравнению со средним баллом 7,4 у врачей. Врачи с большей вероятностью имеют высокий показатель знаний (β =0,498, p<0,05) по сравнению с медсестрами. Результаты исследования свидетельствуют о недостаточности знаний о вакцинации против ветряной оспы, особенно среди медсестер. Рекомендуется организовать занятия по вакцинации против оспы, чтобы подготовить последующие изменения в Национальном календаре иммунизации и внедрения вакцины против ветряной оспы.
Ջրծաղիկը խիստ վարակիչ վիրուսային հիվանդություն է: 2024 թվականին նախատեսվում է Հայաստանի Պատվաստումների ազգային օրացույց ներառել ջրծաղիկի դեմ պատվաստանյութը։ Այս հետազոտությունը նպատակ ունի գնահատելու բուժաշխատողների գիտելիքները, վերաբերմունքը և անձնական համոզմունքները ջրծաղիկ հիվանդության և դրա դեմ պատվաստանյութերի վերաբերյալ՝ Հայաստանում Պատվաստումների ազգային օրացույցում պատվաստանյութի ներդրման նպատակով: Հարցաթերթիկը լրացրել է 779 բուժաշխատող: Հարցվածների 96%-ը կանայք էին՝ 21-ից 77 տարեկան, միջինը՝ 53±11 տարի: Բուժքույրերի գիտելիքի միջին միավորը եղել է 6,7՝ ի տարբերություն բժիշկների 7,4 միջին միավորի: Բժիշկներն ավելի հավանա- կան է, որ բուժքույրերի հետ համեմատած ունեն գիտելիքի ավելի բարձր մակարդակ (β =0,498, p<0,05): Հետազոտության արդյունքներն ընդգծում են, որ ջրծաղիկի դեմ պատվաստումների վերաբերյալ գիտելիքներն անբավարար են հատկապես բուժքույրերի շրջանում: Խորհուրդ է տրվում կազմակերպել ջրծաղիկի դեմ պատվաստումների վերաբերյալ կրթական դասընթացներ՝ հետագայում Պատվաստումների ազգային օրացույցում փոփոխություններ իրա- կանացնելու և ջրծաղիկի դեմ պատվաստումները ներդնելու նպատակով: