bluuebunny/crossref_metadata_2025 huggingface dataset:
Het hart in de war in een verwarrende tijd
Authors: Rienstra Michiel
Published: November 2022

In zijn oratie gaat Rienstra in op de situatie als het hart in de war is bij een patiënt, als er sprake is van een hartritmestoornis zoals atriumfibrilleren, of als er sprake is van hartfalen. Hij beschouwt de consequenties daarvan voor het hart als orgaan, maar ook de impact die dat heeft op het leven van patiënten, vaak letterlijk een verwarrende tijd. Rienstra bespreekt de aanstaande ontwikkelingen binnen de Klinische Cardiologie, het vakgebied waar patiëntenzorg en wetenschappelijk onderzoek samenkomen om diagnosestelling en behandeling van atriumfibrilleren met en zonder hartfalen verder te verbeteren. Rienstra verwacht dat vooral het herontdekken van bestaande medicijnen, technologische ontwikkelingen en artificiële intelligentie om atriumfibrilleren sneller en beter te diagnosticeren en te behandelen, en intensieve samenwerking met andere medisch specialismen en huisartsen belangrijk zullen zijn om de ziektelast voor hartpatiënten zoveel mogelijk verlagen. Verder gaat Rienstra in op de organisatie van zorg en onderzoek want die bepaalt, samen met medisch handelen, de kwaliteit van de zorg. Ondanks dat de kwaliteit, toegankelijk en betaalbaarheid van de Nederlandse gezondheidszorg goed is, kent de organisatie van zorg en onderzoek veel complexe en vaak zelfs verwarrende uitdagingen. Zeker in de huidige verwarrende tijd. Aan de hand van uiteenlopende voorbeelden, waaronder HartNet Noord-Nederland, stelt Rienstra dat om de ingewikkelde uitdagingen in de organisatie van zorg en onderzoek te ontwarren het van groot belang is te werken op basis van vertrouwen, een leidende rol te geven aan artsen en verpleegkundigen, en het wegnemen van verwarring over doelen door te veel focus op het perfectioneren van methoden.
Ensilados de Megathyrsus maximus: Efecto del horario de corte y de la inoculación microbiana
Authors: Patiño-Pardo René , Benítez-Ríos Yesid José , Valdés-Vargas Elkin David
Published: November 2022

Objective. To evaluate the effect of the cutting time and the addition of a microbial inoculum on the fermentative and nutritional characteristics of grass silage of the genus Megathyrsus maximus. Materials and methods. The combination of forage (Tanzania and Mombasa cultivars and corn), cutting time (a.m.-p.m.) and use of additive (with-without) represented the treatments. Was used a completely random design in factorial arrangement. Results. The sensory evaluation was acceptable in all silages, and in those cut at p.m., the dry matter content tended to be higher (p=0.071), as well as digestibility (p <0.02). The addition of inoculum reduced (p<0.05) protein losses. The Mombasa silage presented a higher concentration of dry matter and fibrous components (p<0.001), and that of corn had a higher content of soluble carbohydrates (p<0.001) and a lower pH (3.76) (p<0.001). Fermentation losses were higher in Mombasa and lower in corn (p=0.003). Conclusions. In general, cutting in the afternoon hours improves the digestibility of the silage, and the addition of microbial inoculum reduces protein losses.
Digital Pattern Recognition for the Identification of Various Hypospadias Parameters via an Artificial Neural Network: Protocol for the Development and Validation of a System and Mobile App
Authors: Wahyudi Irfan , Utomo Chandra Prasetyo , Djauzi Samsuridjal , Fathurahman Muhamad , Situmorang Gerhard Reinaldi , Rodjani Arry , Yonathan Kevin , Santoso Budi
Published: November 2022

Background

Hypospadias remains the most prevalent congenital abnormality in boys worldwide. However, the limited infrastructure and number of pediatric urologists capable of diagnosing and managing the condition hinder the management of hypospadias in Indonesia. The use of artificial intelligence and image recognition is thought to be beneficial in improving the management of hypospadias cases in Indonesia.

Objective

We aim to develop and validate a digital pattern recognition system and a mobile app based on an artificial neural network to determine various parameters of hypospadias.

Methods

Hypospadias and normal penis images from an age-matched database will be used to train the artificial neural network. Images of 3 aspects of the penis (ventral, dorsal, and lateral aspects, which include the glans, shaft, and scrotum) will be taken from each participant. The images will be labeled with the following hypospadias parameters: hypospadias status, meatal location, meatal shape, the quality of the urethral plate, glans diameter, and glans shape. The data will be uploaded to train the image recognition model. Intrarater and interrater analyses will be performed, using the test images provided to the algorithm.

Results

Our study is at the protocol development stage. A preliminary study regarding the system’s development and feasibility will start in December 2022. The results of our study are expected to be available by the end of 2023.

Conclusions

A digital pattern recognition system using an artificial neural network will be developed and designed to improve the diagnosis and management of patients with hypospadias, especially those residing in regions with limited infrastructure and health personnel.

International Registered Report Identifier (IRRID)

PRR1-10.2196/42853
A text-based Covibot’s development between organisational needs and AI-based repertoires (Preprint)
Authors: Giuliano Claudio , Ponte Diego , Piras Enrico Maria , Zanutto Alberto , Perini Francesca , Malfatti Giulia , Gios Lorenzo , Corazza Anna , Tretter Veronica , Sacchetti Silvia
Published: November 2022

BACKGROUND

The development of human speech recognition technologies has made increasing progress in recent years. Their role is promising in relation to health information dissemination to facilitate the role of health workers in social distancing by distributing information to the population. Some experiments were developed during the pandemic because traditional channels (e.g. telephone help desk, websites with FAQs, social media) were compromised by the large number of user accesses. For this type of situation, it is necessary to relate the technological development paths to the contexts within which the experiments were carried out.

OBJECTIVE

The paper highlights the text-based experience of a chatbot aimed at meeting the information needs of citizens of a northern region of Italy during the second phase of COVID-19 pandemic emergency. Since 15 April 2021, the chatbot has been accessible from every page of the website of the local Health Authority. Users can type free-form questions and obtain relevant up-to-date answers distilled from different sources of information maintained by the national and provincial authorities.

METHODS

The paper makes its contribution through a mix method research design. The work proposed a retrospective analysis of the engineering processes and the technicalities of setting up the chatbot and building up the wealth of information that became the basis for its responses. The accounts come directly from the working team and the interactions with the various stakeholders involved.

RESULTS

The work highlights how a technology that has arisen within bureaucratic organisational contexts cannot easily draw from the various sources of information, such as news agencies, as the chatbot should provide exclusively trusted content approved by the Health Authority so some questions cannot be answered for lack of authoritative information.

CONCLUSIONS

The study is relevant for three reasons: firstly, it highlights how AI cannot disregard the contexts of use in which it is developed; secondly, it shows that, through rigorous methods, it is possible to plan a trajectory bringing organisations from providing information designed for static channels towards interactive ones. Finally, it shows that a carefully developed strategy to provide thrusted information can generate opportunities for digital transformation in healthcare organisations.
Knowledge, perceptions, and practice of vaccination workers on surveillance of adverse events following immunization in Zhejiang province, China (Preprint)
Authors: lv huakun , pan xuejiao , wang ying , liang hui , lv huakun
Published: November 2022

BACKGROUND

Background: Although vaccines currently approved for routine immunization were safe and effective, frequent adverse events following immunization (AEFI) often cause illnesses and sometimes loss of public trust in immunization programs. Vaccination workers were essential in AEFI surveillance system.

OBJECTIVE

Objective: To determine vaccination workers’ knowledge, perception, and practice towards AEFI surveillance in Zhejiang province, China.

METHODS

Methods: This was a cross-sectional survey involving 192 vaccination workers, within 192 out of 1335 vaccination clinics through being randomly selected. Data were collected using self-administered questionnaires. Data analysis was performed using SAS, version 9.3. Knowledge, perceptions, and practice on AEFI surveillance were summarized using frequency tables. The mean (±standard deviation) value was used as the cut-off for defining good (values ≥ mean) and poor (values < mean) knowledge, perception or practice. Chi-square test and binary logistic regression analysis were used to determine associations between the dependent variables (knowledge, perception, and practice) and independent variables.

RESULTS

Results: The proportions of good knowledge, perception and practice on AEFI surveillance were 78.13%, 57.81% and 66.15%, respectively. Having a higher education background, longer years of experience and previous training were significantly positive determinants on good knowledge, perception and practice on AEFI surveillance.

CONCLUSIONS

Conclusion: Over half of the respondents in this study had good knowledge, perception and practice on AEFI surveillance work. Interventions on improving the vaccination workers’ knowledge, perception and practice on AEFI surveillance should be considered, such as the refreshing training, enhancing the continuing medical education, constructing a blame free culture on reporting as well as the on-job mentorship.
Correction: Parental Factors Associated With Internet Gaming Disorder Among First-Year High School Students: Longitudinal Study (Preprint)
Authors: She Rui , Zhang Youmin , Yang Xue
Published: November 2022

UNSTRUCTURED

This is a corrigendum for MS 33806.
ANALISIS	PENGARUH	PEMBERIAN	PENGATUR	TEGANGAN	BLOWER	PADA	KOMPOR TERHADAP	EFISIENSI	PEMBAKARAN
Authors: Harimurti Danang Tri , Harsono Soni Sisbudi
Published: November 2022

A biomass stove is one of the alternative tools made from bio pellet as a substitute for LPG gas stove (Liquefied Petroleum Gas). Biomass stoves are currently less known by the public due to their traditional use and lack of socialization of biomass fuels. Starting from the problem, biomass stoves currently need further development in order to be used in daily life. Therefore, it is necessary to develop the biomass stove by adding a 12-volt lithium-ion battery as the main power source and a circuit dimmer as a fan speed regulator. The treatment variable in this study is to provide variations in fan speed. Variations used are low, medium, and high fan speeds. The main fuel of the biomass stove is a wood grain bio pellet with the weight of each bio pellet used per treatment as much as 300 grams. The method used in this study used a one-way ANOVA that produced a difference in variation had no real differences and had a noticeable effect on the rate of combustion, the temperature of the fire, and the length of time the water was boiled.
PENGARUH	PEMUPUKAN	LEWAT	DAUN	DAN	WAKTU	DEFOLIASI	PADA PERTUMBUHAN	DAN	HASIL	JAGUNG	(Zea	mays	L.)	VARIETAS	NASA	29
Authors: Pebriandi Asep , Amin Muhammad
Published: November 2022

This study aims to determine the effect of foliar fertilization and corn leaf trimming (defoliation) on the growth and yield of hybrid corn NASA 29. This research was conducted at the Samboja Experimental Garden, Bukit Raya Village, Kec. Samboja, Kutai Kartanegara, East Kalimantan, in April-July 2020. The planting material used was the NASA 29 hybrid corn variety, KNO3 fertilizer, Gandasil D fertilizer, MKP fertilizer. This study used a factorial randomized block design (3 X 3) with 3 (three) replications. The first factor was the type of fertilizer that was applied through the leaves (foliar) which consisted of 3 levels, namely P1 (fertilizer gandasil), P2 (fertilizer MKP), and P3 (fertilizer Rosasol) with a dose of 10 grams/liter each given at the age of 65 DAS. The second factor was defoliation time which consisted of 3 levels, namely D1 (75 days after planting), D2 (defoliation at 82 days after planting), and D3 (defoliation at 90 days after planting). The observed data were analyzed by means of the analysis of variance with the F test at α 5%. if there is a significant difference, it is followed by the Honestly Significant Difference (HSD) test at α 5%. The results showed that the treatment of the type of fertilizer through the leaves and defoliation along with the interactions had no significant effect on the variables of plant height, ear length, and ear diameter, while the treatment of fertilizers by leaf and defoliation and their interactions had no significant effect on the variables of plant height, stem diameter. ear length and ear diameter. P3 fertilizer treatment and defoliation at the age of 82 days after planting (D2) gave the best results on the variable ear weight and dry seed weight.
Migration, Diasporic Realities and the Quest for Home in Chika Unigwe’s On Black Sisters’ Street and Yaa Gyasi’s Transcendent Kingdom
Authors: Ngeh Andrew T. , Nalova Sarah M.
Published: November 2022

This paper preoccupies itself with a close analysis of the concept of migration, diasporic realities and the quest for home in Unigwe’s On Black Sisters’ Street and Gyasi’s Transcendent Kingdom. Migration is a recurrent issue in the world today. Due to one reason or the other, people leave from one geographical location for the other—usually to Europe and America for greener pastures. The study investigates the socio-economic experiences of these African characters in the diaspora and the despair encountered resulting from dreams deferred. In this regard, this paper examines the disillusionment and frustration that characterize Unigwe and Gyasi’s fictional characters in the selected works as they grapple with their expectations and the actual realities in the New World. The work operates on the premise that characters in the texts are induced and motivated by dreams of a better life to immigrate to Europe and America where they end up being trapped in hardship, culture shock and identity crisis. Guided by the Postcolonial theory, this study revealed that, one’s perception of place in which he/she finds himself or herself is determined by the socio-cultural background of place/local; and that success is linked to mentality and personality. The study also found out that characters end up in disillusionment when their expectations are not realized, and this puts them in a melancholic state, hence, their decision to return home.
Design and Implementation of Seven Segment Display Using Reversible Logic Gates
Authors: Dilshad Sk , Akhil Gannu , RajaNandini Simhadri , Unissa Javeria , Chandu Pulapakori Yadav
Published: November 2022

Abstract: An important issue in Seven segment display is heat, but the reversible logic gives less amount of heat dissipation. So, it’s an important role in nanotechnology, less energy complementary metal oxide semiconductor CMOS designs etc. Seven segment displays are most effective devices used in electronic meters, digital calculators, clock radios, digital clocks, odometers, displays in home appliances, etc.In this project, an efficient seven segment display is designed using reversible logic gates CNOT, FREDKIN and PERES gates. Retrievability is a feature which every electronic device wants to posses , In reversible logic gates the inputs and outputs can be retrievable from each other. Backward operation is used in this circuit which allows to retrieve the inputs from the outputs therefore consuming zero power. Reversible logic circuits are also known as lossless circuits, which has neither information loss nor energy loss. The reversible logic operations dissipate less heat and can't erase information.
DOCtalk: A Web Application for Health Care Solutions
Authors: Chavan Prof. Suhas , Ansari Umar , Nagose Vedant , Mugale Akshay , Pawar Akshay
Published: November 2022

Abstract: In this paper we will discuss about how using web technologies, we can design a service or a software which can be used for booking an appointment with a doctor. Many a times, almost every time, we come across a tedious way of traditional way of booking appointments with a doctor, i.e. we have to go to the hospital to book the appointment and wait for the scheduled appointment to come. At some unusual times, the appointment even cancels and the patient is not updated about it. This application will provide everything from knowing about a particular doctor to booking an appointment with him/her. The appointments are made based on time slots interval available in a day
Dental Force Measurement Using Peizoelectric Sensors
Authors: Rokade Harshool , Joshi Vyankatesh , Katkar Samiksha , Jagtap Gauri , Pillai Dr. Priam
Published: November 2022

Abstract: Occlusal load, contact sequence and location are necessary parameters for the study of dental biomechanics, simulation, and clinical treatment planning. There is a huge demand for dental implants, which could accurately and precisely become a substitute to natural teeth, in human beings. To select the most appropriate material for implants as well as designing an artificial tooth, it is important to understand the force exerted by the human jaw while in the process of mastication. To achieve this, there are multiple attempts as well as iterations done through various steps and circuit arrangements, primarily through piezoelectric sensors here. This happens to be the one of the most appropriate ways to measure and quantify the bite force of a tooth. After iterating with charge amplifiers, piezo capacitive and piezo resistive circuit arrangements, moving ahead with the FlexiForce measurement kit and using the A201 sensor which provided with the stable and consistent output for static as well as dynamic loading.
Hybrid Electric AWD Vehicle Kit
Authors: Ahirrao Abhishek , Metkar Shantanu , Avhad Abhishek , Awate Dr. Swapnil , Shinde Prof. Vishal
Published: November 2022

Abstract: The environmental impact of ICE automobiles in the late twentieth and early twenty-first centuries prompted the development of electric vehicles. Electric vehicles have numerous advantages over traditional internal combustion engines (ICE) vehicles, including the fact that they emit no carbon dioxide into the atmosphere. With many advantages of electric vehicles over traditional ICE vehicles, the world is moving toward EVs as a new improved means of transportation. Electric vehicles' tank to wheel efficiency is three times larger than ICE vehicles', and electric vehicles have very low running and maintenance costs. Even though electric vehicles are the best alternative, they do have significant disadvantages that are listed in the problem statement. Our proposal aims to bridge the gap between pure electric and traditional ICE automobiles by combining the primary benefits and advantages of both technologies. The project's main goal is to convert any existing ICE car into the most efficient vehicle possible. Our car can basically run on two distinct independent sources of energy, or even a combination of both. It can function as a pure electric vehicle, a pure ICE vehicle, or a hybrid AWD vehicle (where high amount of power is required). It has been shown that the average city dweller does not drive his or her car for more than 25 kilometers per day, and that the vehicle is parked the majority of the time. As a result, that individual can traverse that distance in pure electric mode, and our vehicle's solar charging mechanism will recover/recharge the energy expended while on the road. As a result, the person will be able to use our vehicle for free to generate sustainable energy. The use of ICE vehicles is rapidly increasing pollution in the environment; even pure EVs are an indirect source of pollution because the bulk of power is still generated by burning coal, thus our vehicle's use will undoubtedly make a significant difference.
El transitado camino a un museo nacional de ciencia y tecnología
Authors: Hidalgo Neydo
Published: November 2022

A través del método histórico y con el uso de fuentes primarias, se repasan, desde los antecedentes sociales y políticos, así como el contexto más inmediato, las acciones que se han venido realizando en el Perú en los últimos 30 años, para la creación de un museo de ciencia y tecnología, a fin de establecer, a modo de hipótesis, algunas conclusiones sobre los motivos por los que no se ha llegado a concretar este ansiado proyecto.
O fenômeno da “selfie” no Museu Oscar Niemeyer: um olhar sobre a instituição, os visitantes e os artistas expositores
Authors: Schnitzler Luiza Moura , de Quadros Claudia Irene
Published: November 2022

Este artigo tem como objetivo promover debates sobre a presença do fenômeno da selfie no museu a partir do olhar da comunicação institucional, dos públicos e de artistas expositores. Para isso, investigou-se o Museu Oscar Niemeyer localizado na cidade de Curitiba-PR/Brasil. Diferentes métodos e técnicas foram adotados nesta pesquisa: uma netnografia, um survey e entrevistas semiestruturadas. Com base nos resultados, é possível afirmar que o museu investigado utiliza a selfie como estratégia de comunicação em suas plataformas de redes sociais digitais, assim como seus visitantes possuem uma prática semanal com o fenômeno e muitos artistas têm pensado na selfie durante o desenvolvimento de trabalhos artísticos.
Energy potential from Areca Palm through Direct Combustion and Pyrolysis in Indonesia: A review
Authors: Setyawan Hendrix Yulis , Sunaryo Sunaryo , Waluyo Budi , Merlya Merlya , Choirun Annisa'u , Nizori Addion , Sahrial Sahrial
Published: November 2022

Global warming that occurs due to rapid population growth and increasing of energy consumption makes energy supply decreases. Energy source from non-renewable energy (fossil fuel) cause increasing greenhouse gas emission level and scarcity of natural resources. This paper reports that agricultural residues especially areca palm wastes had been widely used as an alternative energy source to reducing fossil fuel consumption. About 4.780.000 tones areca palm produced per year around the world and the shell was burned in open air or just thrown in the environment. This work aimed to investigate energy potential from areca palm shell using direct combustion and pyrolysis method also do analysis about this technology from environmental point of view and that contribution for sustainable uses.
Effects of Moisture Content Variation on Some Engineering Properties of Almond Seed (Terminalia Catappa)
Authors: Atteh Bamidele , Olukemi Oguntoyinbo , Bosede Adelola Orhevba
Published: November 2022

The physical and mechanical properties of Almond seed at different moisture content levels of 6.78%, 12.39%, 17.11% and 21.97% were investigated in this study. The physical properties include geometric mean diameter, bulk density and angle of repose; they were determined using standard procedures. The length, width and thickness obtained for the 100 samples of the almond seeds were in the range of 25.42-28.63mm, 23.69-26.63mm, and 7.51-9.18mm respectively. The result shows a high uniformity on the seed sizes and significant variations between the length, width and thickness. The calculated values of the geometric mean diameter and sphericity ranged from 16.48-19.07mm and 64.66- 66.63% respectively. The results of the surface area varied from 853.6-1143.04mm2. The result also indicated a high variation in the surface area of the seeds with respect to the different moisture content levels. The mechanical properties which include rupture force, compressive strength and tensile strength were determined on the seeds. The mechanical properties show that the fracture force and compressive strength decreased from 2689N to 2499N, 410N/mm2 to 398 N/mm2respectivelywith an increase in moisture content (6.78%-21.9%). The tensile strength obtained for moisture levels of 6.78%, 12.39%, 16.11% and 21.9% were 3.20Mpa, 3.90Mpa, 4.20Mpa and 4.60Mpa respectively
Pola Argumentasi dalam Karya Ilmiah Mahasiswa
Authors: Priyanto Priyanto , Wiryotinoyo Mujiyono , Harjono Hary Soedarto
Published: November 2022

Abstrak

Penelitian ini bertujuan untuk menganalisis pola argumen ilmiah dalam skripsi mahasiswa. Aargumen ilmiah merupakan hasil pemikiran mahasiswa yang dituliskan ke dalam bentuk paragraf argumentasi di dalam skripsi. Latar belakang penelitian menjadi fokus penelitian ini. Metode dalam penelitian ini adalah kualitatif dengan pendekatan analisis isi. Data dalam penelitian ini adalah argumen dalam tulisan yang bersumber dari skripsi mahasiswa. Analisis argumen menggunakan teori argumen Toulmin. Hasil analisis menunjukkan bahwa argumen mahasiswa terdiri dari elemen (1) pernyataan posisi (claim), (2) data (grounds), dan (3) jaminan (warrants). Hal ini menujukkan perlu adanya pemahaman dalam menulis argumen ilmiah.

 

Kata kunci: pola argumen, argumen ilmiah.

 

Abstract

This study aims to analyze the pattern of scientific arguments in student thesis. Scientific arguments are the results of students' thoughts which are written in the form of argumentative paragraphs in the thesis. The research background is the focus of this research. The method in this research is qualitative with content analysis approach. The data in this study are arguments in writing that come from students' thesis. The argument analysis uses Toulmin's argument theory. The results of the analysis show that the students' arguments consist of elements (1) position statements (claims), (2) data (grounds), and (3) warrants. This shows the need for understanding in writing scientific arguments.

 

Key: argument pattern, scientific argument.
Calcium acts as a positive regulator of photoprotection by enhancing the interaction between PGR5 and PsbS under low night temperature
Authors: Gu Jiamao , Liu Pengkun , Cui Xiaoyu , Lu Jiazhi , Wang Feng , Qi MingFang , Li TianLai , Liu Yufeng
Published: November 2022

Photoprotection is an important strategy employed by plants to avoid
photoinhibition under stress conditions. However, how photoprotection is
regulated is not fully understood. Here, we show that exogenous calcium
enhances the activity of cyclic electron flow (CEF) and
non-photochemical quenching (NPQ) to regulate photoprotection in
response to low night temperature (LNT) in pTRV2- PGR5 and
PGR5-OE plants. A chloroplast calcium sensing receptor (CAS)
protein was obtained by yeast two-hybrid and verified to interact with
PGR5 via bimolecular fluorescence complementation (BiFC) and luciferase
complementation imaging assays (LCA). Protein interaction analysis
showed that PGR5 also interacts with PsbS. Interestingly, CAS promotes
the interaction between PGR5 and PsbS, and the level of PGR5 and
PsbS transcripts is reduced in cas mutants. NPQ is
significantly reduced in psbs mutants, but this phenotype is
attenuated after calcium application under LNT. Taken together, these
results demonstrate that calcium signaling increases electrical
signaling and energy dissipation efficiency under LNT conditions.
The ever-lasting green tides: what can we do?
Authors: Ren Cheng-gang , Qin Song
Published: November 2022

Macroalgal blooms (Green tides) are occurring more frequently in many
regions of the world because of the combined effects of increasingly
intense human activity and climate change. In the last decade, the
world’s largest Ulva prolifera green tide has become a recurrent
phenomenon, appearing every summer in the southern Yellow Sea, China,
and it is getting worse. Green tides can hurt coastal tourism and
eradicate aquaculture and artisanal fishing. Eutrophication in nearshore
waters is the ultimate explanation for the explosive growth of the
macroalgal biomass, but the specific course of each nearshore green
tides is often complex and requires in-depth and extensive research to
develop effective mitigation strategies. It is becoming increasingly
urgent to prevent and control the bloom at the early stage, promote the
ecological virtuous cycle, and efficiently salvage and use these
valuable raw materials.
Effective Endodontically Treated Incisors with External Root Resorption during Orthodontic Movement: A Case Report
Authors: Su Rugan , Li Song , Zhang Chen , Hou Jingyi
Published: November 2022

This case report describes a 21-year-old orthodontic patient experienced
the external apical root resorption of maxillary central incisors with
pulpitis during the orthodontic movement. The active cooperation of
orthodontists and endodontists demonstrated the satisfactory treatment
outcome and prevention of further apical root resorption.
De Novo Biosynthesis of Sakuranetin from Glucose by Engineered Saccharomyces cerevisiae
Authors: Zhong Weihong , Tu Shuai , Xiao Feng , Mei Chengyu , Li Shuang , Qiao Pei , Huang Ziyan , Gong Zhixing
Published: November 2022

Sakuranetin is a plant-natural product, which has increasingly been
utilized in cosmetic and pharmaceutical industries for its extensive
anti-inflammatory, anti-tumor, and immunomodulatory effects. Sakuranetin
was mostly produced via extraction technology from plants, which is
limited to natural conditions and biomass supply. In this study, a novel
strategy to produce sakuranetin via de novo synthesis from
glucose by engineering S. cerevisiae was introduced .
After a series of heterogenous genes integration, a biosynthetic pathway
of sakuranetin from glucose was successfully constructed in S.
cerevisiae which sakuranetin yield reached only 4.28 mg/L. Then, a
multi-module metabolic engineering strategy was applied for improving
sakuranetin yield in S. cerevisiae: (1) adjusting the copy number
of sakuranetin synthesis genes; (2) removing the rate-limiting factor of
aromatic amino pathway and optimizing the synthetic pathway of aromatic
amino acids to enhance the supply of carbon flux for sakuranetin; (3)
introducing acetyl-CoA carboxylase mutants
ACC1 and knocking-out
YPL062W to strengthen the supply of malonyl-CoA which is another
synthetic precursor of sakuranetin. The resultant mutant S.
cerevisiae exhibited a more than 10-fold increase of sakuranetin titer
(50.62 mg/L) in shaking flasks. Furthermore, the sakuranetin titer
increased to 158.65 mg/L in a 1-L bioreactor, which is the highest
sakuranetin titer among all publications reported yield of the
engineered microbial cell.
Consequences of cross-season demographic correlations for population viability
Authors: Layton-Matthews Kate , Reiertsen Tone , Erikstad Kjell Einar , Anker-Nilssen Tycho , Daunt Francis , Wanless Sarah , Barrett Robert , Harris Mike
Published: November 2022

Demographic correlations are pervasive in wildlife populations and can
represent important secondary drivers of population growth. Empirical
evidence suggests that correlations are in general positive for
long-lived species, however little is known about the degree of
variation among populations in relation to local conditions. For three
widely geographically separated Atlantic puffin populations
(Fratercula arctica), we compared the relative importance of
survival-reproduction correlations for two cross-season correlations,
reflecting either effects of non-breeding season or breeding season
conditions. Demographic rates and their correlations were estimated with
an integrated population model, and their respective contributions to
variation in population growth were calculated using a transient-LTRE.
Demographic correlations were positive for all three populations, but
their strength differed. By comparing three populations with
geographically distinct foraging areas throughout the year, this study
shows that demographic correlations are, in part, driven by
environmental conditions, which impacts their population viability and
vulnerability to environmental change.
Perioperative Management of Duodenal Carcinoid without Octreotide: a case report and review of the literature
Authors: Peng Qing , Liu Limei
Published: November 2022

Background: Octreotide has become a common choice for the
treatment or prevention of carcinoid syndrome in route practice.
However, its role in perioperative prevention and treatment of carcinoid
crisis is controversial. Case Summary: We reported detailed
perioperative management for a carcinoid crisis in a 28-year-old male
patient diagnosed with duodenal carcinoid including anesthetic
considerations and suggestions for applying octreotide. Approximately
30min after the induction of anesthesia, and immediately after
manipulation of the duodenum, a carcinoid crisis was triggered. Soon
after symptomatic treatment of this crisis, the vital signs and flushing
gradually returned to normal. The surgical procedure lasted nearly 6
hours. As the patient did not have any clinical manifestations related
to carcinoid syndrome, no octreotide was administered during this
period. After the surgery, he was transferred to the intensive care
unit. His postoperative course was uneventful with discharge 21 days
after the initial procedure. Conclusion: Duodenal carcinoid
crisis is rarely treated without octreotide. The patient had a good
outcome after carefully preoperative preparation and timely symptomatic
treatment. We hope to provide case support for standard perioperative
management of carcinoid crisis in the future by summarizing the
successful experience of this case.
Contralateral structure and molecular changes after severe unilateral brain injury
Authors: Zhuang Yuan , Dong Jinqian , Ge Qianqian , Li Hao , Zhang Bin , Yang Mengshi , Lu Shenghua , Niu Fei , Xu Xiaojian , Liu Baiyun
Published: November 2022

Severe unilateral brain injury has a poor prognosis and results in
global brain changes, especially in corresponding contralateral regions.
Understanding molecular changes in the contralateral hemisphere,
especially gene regulation, may aid in discovering therapies to enhance
recovery. In this study, we performed right motor cortex resection to
simulate severe unilateral brain injury in male rats and investigated
changes in glial and synaptic immunohistology and morphology in the left
motor cortex. Transcriptome analysis was performed to examine changes in
gene expression. 7 days after cortical resection, the number of reactive
astrocytes and microglia with hypertrophic morphology and expression of
synapsin-1 in the contralateral motor cortex was higher in the
experimental group. The molecular alterations were consistent with
observed structural changes such as staggered dendrites and presence of
synapses around astrocytes. Genome-wide transcriptomic data indicated
that pathways related to inflammation, synapses, and axonal regeneration
were significantly upregulated in the contralateral cortex of the
cortical resection group. Furthermore, transcription factors such as
NF-KB1, Rela, STAT3, and Jun, were predicted to regulate the
contralateral changes. Quantitative reverse transcription polymerase
chain reaction showed that the mRNA level of Cacna1c, Tgfb1, and Slc2a1
which were regulated by STAT3, JUN and NF-KB in the contralateral cortex
was higher in the cortical resection group. In conclusion, the
contralateral response to unilateral brain injury was related to
inflammatory and synaptic activity.
Hexaarylbiimidazole-based polyurethane positive photoresists for UV lithography
Authors: Luo Peng-Fei , Xiang Shi-Li , Ren Ying-Yi , Peng Ling-Yan , Huang Jun-Dan , Hong Pan , Yu Qi , Li Chong , Zhu Ming-qiang
Published: November 2022

Photochromic hexaarylbiimidazoles (HABIs) enable reversible
transformation between HABI and triphenylimidazole radicals (TPIRs) upon
UV light irradiation, which have been applied in photo-patterning,
super-resolution imaging, photoinduced self-healing materials and
photomechanical hydrogels. Here, we designed and prepared a novel kind
of polyurethane (PU) photoresist based on photo-cleavable HABI
cross-linkers (HABI-PU), linear PU backbone and additive
tert-butylhydroquinone (TBHQ) radical quencher. Upon UV light
irradiation, the C-N bond inside HABI unit is broken, causing the
transformation of HABI into two TPIRs which are subsequently quenched by
TBHQ. Therefore, the cross-linking points of HABI-PU in UV irradiation
area were broken, forming flexible PU polymer chains with declined
molecular weight, which can be dissolved in developer. HABI-PU films
show excellent photosensitivity as a positive photoresist in
photolithography. The reaction mechanism between HABI and TBHQ was
studied by UV-vis absorption spectra, electron paramagnetic resonance
(EPR), mass spectra and nuclear magnetic resonance spectra. The
lithographic patterns were characterized through metallurgical
microscope and scanning electron microscope with a resolution at about 5
µm.
Customer-Focused Supply Chain Strategy Developing 4 Rs Model in Apparel Industry
Authors: Ahmed Shuaib
Published: November 2022

In CFSCS the chief achievement is to counter consumer demand in real-time, that act will cut down the cost to experience productivity at an economical scale and give a chance to customers to practice a superior experience. The organizations practicing or implementing a strong CFSCS (customer-focused supply chain strategy) are performing at their excellence in the sales sector, share in the market, productivity, and high level of customer satisfaction. The supply chain mechanism is highly customer focused in CFSCS, Chief elements of the success are highly dependent on the 4Rs model (responsiveness, resiliency, reliability, and realignment) and provide better services at low cost as compared to the traditional supply chain model. The study explores that the 4Rs model in CFSCS is a chief driver for this purpose we develop various frameworks. Our field of proving the CFSCS 4Rs model is in the apparel industry.
Parasitic infections in the practice of a phthisiologist (clinical case)
Authors: Aksenova V. А. , Klevno N. I. , Kazakov A. V. , Pakhlavonova A. D. , Sokolskaya E. A. , Kavtarashvili S. M. , Romanenko V. A. , Stepanenko N. S.
Published: November 2022

Parasitic infections are widespread throughout the world and are especially common in childhood. The absence of pathognomonic symptoms in liver diseases is characteristic. We presented clinical observation with asymptomatic echinococcosis with damage to the respiratory organs and liver. During the fluorographic examination, changes in the lungs were revealed, in connection with which she was sent for a consultation with a phthisiatrician. In the TB hospital, with the help of a comprehensive examination and modern telemedicine technologies, changes were identified in lungs and in the liver. This clinical observation showed that it is necessary to conduct a comprehensive examination before prescribing specific anti-tuberculosis treatment. Increasing physicians' knowledge of parasitic diseases could increase the early detection.
DEPRYWACJA MATERIALNA POLSKICH GOSPODARSTW DOMOWYCH W PIERWSZYM ROKU PANDEMII COVID-19
Authors: Dudek Hanna
Published: November 2022

W pracy rozpatrzono sześć symptomów deprywacji materialnejpolskich gospodarstw domowych. W analizie ekonometrycznej wykorzystanomodele logitowe dla zmiennych binarnych. Parametry tych modeli zostałyoszacowane na podstawie danych indywidualnych zebranych w ramachEuropejskiego Badania Dochodów i Warunków Życia Ludności – EU-SILC.Stwierdzono, że w okresie 2019-2020 r. zmniejszyło się występowanierozpatrywanych symptomów deprywacji materialnej w Polsce. Ponadto,wskazano na rolę takich cech społeczno-ekonomicznych, jak edukacja,wartość dochodów, miejsce zamieszkania, typ gospodarstwa domowego,obecność osób niepełnosprawnych oraz osób bezrobotnych. Cechy te istotniewpływały na ryzyko deprywacji materialnej w Polsce w latach 2019-2020
Economic growth, energy consumption, and trade openness nexus: Evidence from net energy importing middle-income countries
Authors: Sarıgül Haşmet , Apak Sudi
Published: November 2022

The study explores both the long- and short-run liaisons between three conceptual dimensions: economic growth, energy consumption, and trade openness in 29 net energy importing middle-income economies using annual data from 1990 to 2019. We hereby assess ARDL models which examine the long-run links by integrations in between these three conceptual variables, and additionally Dumitrescu-Hurlin and Granger causality tests for panel and individual country models, respectively. For panel country samples, we reveal bidirectional causality connection between trade openness and economic growth along with unidirectional causalities from economic growth to energy consumption and from energy consumption to trade openness in the short-run. Bidirectional positive feedback relationships stand between economic growth - energy consumption and trade openness - energy consumption in the full sample and the upper middle-middle economies subsample in the long-run. Findings for individual country estimations reveal significant long-run relationships between energy consumption and economic growth in 12, energy consumption and trade openness in 6, and economic growth and trade openness in 9 of the middle-income economies examined.
Populism and the migrant crisis in Europe - political implications
Authors: Lutovac Zoran
Published: November 2022

Dealing with the migrant crisis in Europe has shown that the regulations, principles, and values of the European Union are overshadowed by the individual interests of its member states. On the one hand, EU member states have faced internal political challenges caused by populism, while on the other hand, there has been a lack of rapid, coordinated, and synchronised measures to solve the problems at hand. The mass influx of migrants from Asia and Africa to Europe indicates demographic shifts on a historic scale and possible global consequences, but EU member states have been observing the issue and are still observing it primarily from their own national point of view. A comparative analysis of electoral support for populist parties and movements in Europe since the beginning of the migrant crisis has led to an indicative conclusion that there is a direct correlation between increasing support for populists and the large-scale migrant crisis. The significant influx of migrants has contributed not decisively, but to a significant extent to the creation of a great populist wave that has engulfed almost all of Europe.
Striped Flint in Archaeological Materials Around the Outcrops of the Kraków-Częstochowa Striped Flint Variety
Authors: Sudoł-Procyk Magdalena , Malak Magdalena , Binnebesel Hubert , Krajcarz Maciej T.
Published: November 2022

Many varieties of siliceous raw materials can be found in the territory of Poland. Known exclusively from in situ outcrops in the Holy Cross Mountains area until recently, striped flint is distinctive in terms of its technical and visual features. The authors present the state of knowledge about the variety of striped flint from the Ryczów Upland, the outcrops of which were found only about a decade ago. New data obtained from the central part of the Kraków-Częstochowa Upland has cast interesting light on the issues of the origin of striped flint and the ways it was used by the prehistoric communities inhabiting the region. Identifying the sites of siliceous rocks outcrops, extraction and distribution are extremely important at not only the local but also trans-regional level.
Editorial
Authors: Werra Dagmara , Woźny Marzena , Krajcarz Maciej , Sudoł-Procyk Magdalena
Published: November 2022

The earliest research on the siliceous raw materials in the territory of Poland dates back to the first years after World War I. A patriarch of these studies was an archaeologist Stefan Krukowski (1890–1982). Together with Jan Samsonowicz (1888–1959), then a young geologist, they undertook a grand survey focused on flint deposits and prehistoric exploitation sites. The year 2022 brings a centennial celebration of their most prominent discovery: Krzemionki (Fig. 1). Exactly on July 19th, 1922, J. Samsonowicz realized that the unusual landscape of Krzemionki is a remnant of a prehistoric flint mine; he later wrote about this: “It came out that the mentioned pits are prehistoric mining shafts, filled with debris and soil” (Samsonowicz 1923: 22, translation by the Editors).
Elżbieta Trela-Kieferling (ed.), Nakopalniane pracownie krzemieniarskie z okresu neolitu w Bęble, stan. 4, woj. Małopolskie [Neolithic Flint Workshops at the Mine in Bębło, Site 4, Małopolska]. Kraków 2021, Muzeum Archeologiczne w Krakowie. Biblioteka Muzeum Archeologicznego w Krakowie vol. X, pp. 204, 68 illustrations (57 colour, 11 black-white), 72 plates and 37 tables
Authors: Werra Dagmara H
Published: November 2022

This monograph on the Neolithic flint workshops of the Bębło mining complex (Cracow district, Lesser Poland Voivodeship) appeared in 2021, published by the Archaeological Museum in Kraków with financial aid from the Ministry of Cultural and National Heritage, National Heritage Board of Poland and the Marshal’s Office of the Małopolska Region. The editor of the publication is Elżbieta Trela-Kieferling. The book appeared in the series „Biblioteka Muzeum Archeologicznego w Krakowie” [The Library of the Archaeological Museum in Kraków], edited by Dr hab. Jacek Górski. It is the tenth volume in the series, which has appeared since 2006, and is a commemorative volume, dedicated to the initiator of the series, Dr. Jacek Rydzewski.
Meaning Cognitive Theory with Lesson Study to Improve the Quality of Learning in Low School
Authors: V.Ramasamy Kumanan A/L , Jiwarathnam Sarimilla A/P
Published: November 2022

This article presents a proposal to improve teaching excellence among elementary school students by using the Lesson Study (LS) approach. LS is a model of professional development of educators originating from Japan. In the LS process, a group of educators systematically reviews the practice of educators with the aim of producing a more effective teaching and learning process. It begins by identifying certain subject units that have problems in the teaching and learning process. Thus, objectives were set to provide the focus and direction of the research. Furthermore, the process of planning, teaching, observing, and evaluating lesson units is carried out. This process is repeated. Finally, a study report is generated and the LS findings are shared with other educators. This LS approach can mobilize pedagogical knowledge and skills among educators. It provides opportunities for educators to collaborate to overcome difficulties encountered in teaching subject units or methodologies. Thus, this approach is expected to provide benefits in improving students' understanding and academic achievement. Proposals regarding the implementation of LS in One of Primary Tamil School Malaysia will be discussed in this article.
Lesson Study: A Collective Concern for Students’ Learning Improvement
Authors: Suwartono Tono , Abdulloh Abdulloh , Khomsatun Khomsatun
Published: November 2022

Having a teaching art for a teacher has been a compulsory nowadays. Beside the basic requirement, the mastery of the content and also good lesson instructions are needed in the classroom. The skill or competency sometimes become the problems faced by the teacher in implementing a lesson plan. By understanding the cases, the teacher has to be aware of alternatives to best classroom activities. The lesson study is suggested to be an alternative solution for implementing a lesson plan. This study aimed to show how collaborative learning from the teachers can create collective concern among the teachers. This research employed a literary study directed for providing some perspectives and evidences to prove that teacher’s competence can be developed through collaborative learning. The results of this study has indicated that the teachers are strongly encouraged to apply the lesson study in attempt to find the best way for implementing the lesson plan because it can build a learning community among teachers, overcome ineffective learning practice based on clinic stages, and be implemented at any level.