bluuebunny/crossref_metadata_2025 huggingface dataset:
Оцінка ефективності додаткового професійного навчання на базі установи охорони здоров’я
Authors: Bogomaz V. M. , Rymarenko P. V.
Published: November 2023

Наведено результати апробації методики навчання медичних працівників на робочих місцях як складової сучасної моделі управління якістю медичних послуг. Проведено статистичний та якісний аналіз ефективності додаткового навчання з надання екстреної медичної допомоги на базі закладу охорони здоров’я з використанням адаптованої навчальної програми та спеціальних манекенів. Під керівництвом сертифікованого інструктора фокус-група з 53 лікарів та молодших медичних спеціалістів навчалась 22 год. Згідно з результатами анкетування учасників навчання, рівень самооцінки їх знань та навичок достовірно підвищився. Також достовірно збільшилась кількість правильних відповідей при формалізованому тестуванні обох категорій працівників. Використання андрагогічної моделі навчання, манекенів-симуляторів і тренування у невеликих групах за місцем роботи створювали максимально сприятливі умови для ефективного індивідуального та групового відпрацювання практичних навичок з екстреної медицини.
On the Phonology of Non-Liturgical Editions of the Glagolitic Press in Senj
Authors: Blažević Krezić Vera , Crnić Novosel Mirjana
Published: November 2023

In this paper, focusing on three Croatian Glagolitic editions printed in Senj as examples, the authors attempt to form a clearer linguistic picture of the non-liturgical works printed at Senj’s Glagolitic printing press, particularly in light of previously established conceptions of the 16th century Croatian literary language. Combining the vowel and consonant features of the Senj editions Korizmenjak, Mirakuli, and Naručnik, an effort was made to describe in detail the linguistic characteristics of the given level of description. At the same time, special attention was given to both Church Slavonic and vernacular (Čakavian) features. the analysis confirms that many of the described features are characteristic not only of the Čakavian of that time, but also of Croatian Church Slavonic. This indicates, on one hand, a tendency to preserve the literary tradition of the printed word, but on the other hand, also a confirmation of Čakavian phonological features.
Tantangan Penyediaan Rumah Khusus yang Berkearifan Lokal
Authors: Panggabean Elias Wijaya
Published: November 2023

Rumah Khusus adalah rumah yang diselenggarakan untuk memenuhi kebutuhan khusus, yakni rumah untuk  masyarakat terdampak bencana, masyarakat yang direlokasi akibat dampak program pembangunan,  masyarakat atau petugas yang bertempat tinggal di wilayah perbatasan, masyarakat yang tinggal di daerah  terpencil, tertinggal dan terluar (3T), serta untuk kebutuhan khusus lainnya. Selama ini desain rumah khusus  yang dibangun memiliki tipikal yang sama di semua daerah. Sehingga muncul kesan kaku, monoton, dan kurang merepresentasi identitas budaya lokal daerah tersebut. Peraturan yang ada sebenarnya telah memberikan ruang untuk mengeksplorasi nilai-nilai sosial budaya lokal pada desain rumah khusus, namun implementasinya di lapangan masih sangat sedikit. Dampaknya adalah identitas masyarakat lokal dalam wujud desain bangunan, semakin lama akan semakin memudar dan dikhawatirkan akan hilang. Penelitian ini akan menggali tantangan yang menjadi penghambat dan penulis mencoba merumuskan strategi untuk mendorong penyediaan rumah khusus yang menerapkan kearifan lokal di seluruh wilayah Indonesia, dengan menggunakan pendekatan eksploratif dan dianalisis dengan metode SWOT. Dari hasil analisis diperoleh beberapa strategi kebijakan yang dapat mendorong penerapan nilai kearifan lokal dan budaya dalam penyediaan rumah khusus. Dengan demikian rumah khusus yang dibangun mampu menunjukkan identitas budaya lokal masyarakat penerima manfaat rumah khusus.
Efek Rasio Ketinggian dan Luasan Lantai Setback Dua Arah Terhadap Respons Dinamik Struktur
Authors: Cornelis Remigildus , Lewlelek Raynaldo , Kumalawati Andi
Published: November 2023

Struktur bangunan setback adalah jenis struktur dengan luasan lantai yang berkurang akibat tonjolan ke dalam atau memiliki suatu lonjakan bidang lantai. Beberapa faktor yang mempengaruhi respons struktur dengan desain setback terhadap beban gempa meliputi rasio luasan setback, rasio tinggi setback, arah setback (satu arah atau dua arah), dan letak setback (simetris atau asimetris) akan ditinjau. Tujuan dari penelitian ini adalah untuk mengidentifikasi dampak dari rasio luasan dan ketinggian lantai setback dua arah terhadap respons dinamik struktur menggunakan beberapa variasi model setback yang sesuai dengan persyaratan SNI 1726:2019. Dalam penelitian ini, terdapat sepuluh model struktur yang diteliti, terdiri dari satu model struktur tanpa setback (model kontrol) dan sembilan model struktur dengan desain setback dua arah. Respons struktur pada model-model ini terhadap beban gempa dianalisis menggunakan metode respons spektrum. Temuan penelitian menunjukkan bahwa variasi rasio luasan dan ketinggian setback yang semakin meningkat akan mengakibatkan penurunan perpindahan antar tingkat, gaya geser dasar, gaya geser antar tingkat, dan kekakuan struktur antar tingkat. Pada lantai setback, simpangan antar tingkat, momen maksimum balok dan momen maksimum kolom antar tingkat akan semakin besar sebaliknya akan semakin kecil pada lantai tingkat non setback. Hasil analisis menunjukkan bahwa struktur dengan rasio luasan dan ketinggian setback yang memenuhi persyaratan SNI 1726:2019 adalah struktur setback jenis MRL36 yaitu jenis struktur dengan rasio luasan setback 36% dari luasan total dan rasio ketinggian setback 25% dari tinggi total struktur.
Universals of Chinese Culture and Their Manifestation in Ceremonial Music
Authors: Rosul Tetiana
Published: November 2023

The purpose of the study is to determine the range of basic cultural universals, that formed the basis of Chinese civilization and revealed its originality and ethnic identity, as well as to trace their influence on the ancient national ceremonial music tradition. The research methodology is based on the use of cross-cultural and systematic methods, a combination of historical, source, axiological, and musicological approaches. The scientific novelty of the study lies in the fact that the ethos of music of ancient Chinese culture is substantiated, the performance features of ceremonial performances are revealed, and the idea of aesthetic constants and symbolism of music in the Celestial Empire is expanded. Conclusions. The uniqueness of Chinese culture lies in its impressive stability, internal continuity of forms and stylistic unity tested by hundreds of generations. Such qualities are determined by the ritualistic model of the Celestial culture. The unique picture of the world, conditioned by the experience of adaptation to complex natural and climatic conditions and ideas about the organization of the universe, objectified several cultural universals, which became the cornerstone of Chinese civilization. They include the basic elements of the five-point scheme: Tao, Tian, Li, Zhen, and Qi. In a general form, they record the socialization experience of individuals, express the values of the ethnic group, and function as a complete system, where each element is closely related to the other. Although none of these universals are directly related to music, they are all embodied in the musical practice of the Celestial Empire. Endowing music with metaphysical properties and functions led to the formation of ideas about “perfect music” as a special creative activity capable of beneficially influencing the individual, society, and the cosmos. In cosmologically interpreted music and its associated rituals, Confucians saw a “tuning fork” that tunes the management and education of the people to cosmic rhythms. Therefore, musical art acquired an ontological status, and the parameters of sound matter (pitch, rhythm, timbre, loudness, tempo, form) became a subject not only of aesthetics but also of politics and philosophy.
Two- and Three-Row Xylophones in the Musical and Instrumental Culture of Europe in the 19th – First Half of the 20th Century
Authors: Oliynyk Dmytro
Published: November 2023

The purpose of the research is to analyze the design features of European xylophones with two- and three-row plate arrangements, to establish the modes, range, various systems of sound ordering and use in folk and professional performance of the nineteenth – first half of the twentieth century. The research methodology is based on a set of specific and general scientific methods: instrumentology – for analyzing the design of instruments; comparative and typological – for studying the types of xylophones; ethnomusicology – for studying the use of xylophones in folk and professional music. The scientific novelty of the study is the introduction to the scientific circulation of materials little known to the general public concerning the functioning of two- and three-row xylophones in the European folk and professional musical culture of the nineteenth and first half of the twentieth centuries. Conclusions. From the Middle Ages to the end of the eighteenth century, single-row xylophones with a limited range were used in folk and professional performances. At the beginning of the nineteenth century, the process of combining two single-row xylophones into a single system began in order to increase the range and overcome tonal limitations. The first double-row xylophones appeared in Austria (Tyrol) and Germany, from where they spread to Central and Western Europe. In the middle of the nineteenth century, two new systems of arranging two rows of plates emerged in Germany and Switzerland – “in the tooth” and on the principle of a piano keyboard. In the second half of the nineteenth century, a three-row system of xylophone plate arrangement emerged in parallel with the two-row system. In folk and professional practice, three-row xylophones were used mainly in Germany, Hungary, and Romania. In Germany, the three-row system was not as widespread as the two-row system, but in the traditional instrumentation of Hungary, it was the main one and had a long tradition of performance on this type of xylophone.
Phonetic Method of Voice Production in the Context of Teaching the Educational Component “Vocal and Choral Technique”
Authors: Komarnitskyi Yaroslav
Published: November 2023

The purpose of the research is to characterize and analyze some phonetic method technologies of academic voice training, revealing their effectiveness in overcoming the vocal problems of a beginner singer based on my own experience of working with students within the educational component “Vocal and Choral Technique”. The research methodology the article uses the following methods of literature analysis on the chosen topic; classification of basic phonemes of the Ukrainian language; distinguishing the features of articulation formation of vowels and consonants; the method of deduction aimed at analyzing a certain phonetic concept and the work of the articulation apparatus through the prism of vocal phonation; the method of induction is used to analyze the techniques of traditional application of certain vocal exercises in the context of general phonetic patterns; observations based on experience of working with students with vocal problems. The scientific novelty of the study is to analyze the application of elements of the phonetic method of voice production based on their own practical experience of teaching the educational component “Vocal and Choral Technique” in the context of the formation of professional skills and knowledge. Conclusions. In the proposed study, we have considered important, in our opinion, aspects of the phonetic method of voice production. In the context of teaching the educational component “Vocal and Choral Technique”, which is aimed at improving the individual vocal technique of a choral singer and developing the skills of practical interaction between vocalists in the context of ensemble and choral singing, the teacher needs to develop a student-centred, individualized system of training students, which will certainly include technically sound techniques of outstanding vocal teachers and scientists. In the process of mastering this course, it is important for students to understand how articulators should work, feel the possible presence of muscle clamps, and acquire the skills of muscle self-control.
Закон України «Про медіа»: історія ухвалення, позитиви, недоліки, перестороги
Authors: Савенко Олександр
Published: November 2023

У статті йдеться про десятилітню політичну, парламентську й журналістську боротьбу, пов’язану з розробкою та прийняттям одного з найбільш обговорюваних та складних законів в історії українського парламентаризму – Закону «Про медіа». Автор досліджує загальну ситуацію, що склалася в інформаційному просторі України протягом останніх десяти років; аналізує причини тривалої відсутності й затягнення процесу створення цього фундаментального закону в інформаційній сфері. Розглядається питання, чому наукові дослідження на цю принципову та гостру тему відсутні або обмежені в українському науковому доробку. Зазначено найважливіші моменти боротьби за формування змістового наповнення закону та аналіз його відповідності провідним принципам європейських стандартів. Автор відслідковує реакцію українських та міжнародних організацій, експертів і фахівців на внутрішній інформаційно-законодавчий конфлікт в Україні, який вийшов на світову арену. Проаналізовано вплив цих внутрішніх і зовнішніх чинників на зміни та доповнення до остаточного варіанту законопроєкту. Особливу увагу приділено проблемі необґрунтованого розширення функцій і повноважень Національної ради України з питань телебачення і радіомовлення, що стало предметом критики та обговорення як в Україні, так і за кордоном. У статті проаналізовано переваги та недоліки нового закону «Про медіа»; зроблено спробу окреслити перспективи його впровадження й передбачити найсуттєвіші труднощі та проблеми, пов’язані з реалізацією його основних цілей і завдань.
Газета «Харбінський Вістник»: епізод історії українського пресовидання у Китаї
Authors: Дроздовська Олеся
Published: November 2023

Останніми роками спостерігається зростання уваги науковців до української преси, яка впродовж 1917–1944 рр. виходила в Китаї. Українське пресовидання тут розвивалося хвилеподібно: були роки, коли світ побачило кілька видань, і роки повного вакууму. Нині відомо двадцять три часописи, які у зазначений період виходили в Харбіні, Ціндао, Шанхаї. Найбільш плідними були 1930–1940-ві рр., коли представники української еміграції в Китаї заснували п’ятнадцять часописів, зокрема такі успішні пресові проєкти, як «Маньджурський Вістник» (Харбін, 1932–1937) і «Український Голос на Далекому Сході» (Шанхай, 1941–1944). Проте, допоки справа дійшла до видавання першого з них, було здійснено низку спроб забезпечити українців у Китаї власним пресовим органом. Серед них – газета «Харбінський Вістник», яка виходила у 1924–1925 рр. Єдиний відомий нині примірник цього видання зберігається у Львівській національній науковій бібліотеці України імені В. Стефаника, що дає нам право говорити про нього як про бібліографічну рідкість.

Мета дослідження полягає у вивченні історії функціонування «Харбінського Вістника», визначенні проблемних напрямів опублікованих матеріалів, розкритті його місця й ролі в житті української діаспори Китаю. Для досягнення окресленої мети застосовано систематичний та комплексний підходи до вивчення історії української преси у Китаї; використано такі методи: історичний, мікроісторичний, компаративний, якісний контент аналіз, індукція та узагальнення. У процесі дослідження вивчено стан розробки теми, з’ясовано умови функціонування видання, визначено його завдання, здійснено аналіз тематичного спектра публікацій, встановлено коло авторів.

У висновках зазначається, що газета «Харбінський Вістник» не є унікальним пресовим проєктом українців Китаю з точки зору багатства тематичного наповнення. Вона не містить яскравих журналістських, публіцистичних, літературних текстів. Однак фактом свого існування в інформаційному полі Далекого Сходу часопис заявляв про присутність українців у цьому регіоні й привертав увагу до їхніх проблем. Наголошується, що вивчення епізодів історії української пресової журналістики ХІХ–ХХ ст., якими є історія окремих видань, формує підґрунтя для підготовки аналітичних праць, присвячених дослідженню комплексу часописів, пов’язаних між собою або періодом, або місцем виходу, або видавцем/редактором, або напрямом тощо.
Проблематика впровадження штучного інтелекту в сучасних ЗМІ та медіатехнологіях
Authors: Ситник Олексій
Published: November 2023

Актуальність. Спрощення роботи, зменшення її обсягів і збалансованість ресурсів, що уможливлюється технологіями штучного інтелекту (ШІ), зумовлюють упровадження його в різних сферах медіагалузі. З’являються можливості, зокрема для генерації контенту, розроблення концепцій (інформаційних, візуальних, структурних), для виробництва мультимедійного контенту, титрів, трейлерів до фільмів, сюжетів, які значно ефективніше будуть взаємодіяти та привертати увагу аудиторії. Активне використання алгоритмів та платформ штучного інтелекту дає змогу використовувати їх для підвищення ефективності низки часозатратних завдань – пошук та збір контенту, опрацювання пулів даних, створення та розповсюдження інформаційного продукту різними каналами, а також для рекомендацій мультимедійного контенту на основі релевантності, користувацького досвіду та попередніх принципів залученості аудиторії. Перед сучасними журналістами технології ШІ відкривають можливість миттєвої фільтрації фейкових новин, перевірки фактажу, джерел тощо, використовується для швидкого створення ілюстрацій, інфографіки, інтерактивних візуалізацій даних. Штучний інтелект має великий потенціал у формуванні відбору контенту для споживачів інформаційного продукту, підбору релевантного контенту в ході комунікацій і уточнень, які аналізує ШІ в процесі взаємодії з користувачем. Водночас практичні аспекти впровадження ШІ в медіа (напрями, можливості, переваги, недоліки, правила, принципи, технології, методи) потребують теоретичного обґрунтування та систематизації методологічних питань. Науковий аналіз технологій та потенціалу штучного інтелекту (ШІ) дасть змогу розробити методологію продуктивного використання його для підвищення ефективності виробничих та видавничих процесів сучасних медіа та функціонування медіасфери загалом, зокрема обґрунтувати принципи застосування в різних сферах медіагалузі, окреслити регламент та правові аспекти його роботи.

Мета наукової розвідки – виявити й обґрунтувати виробничі сфери впровадження та базові принципи застосування штучного інтелекту в новітньому медіасередовищі, визначити та окреслити етичні моменти цього явища в сучасному журналістикознавстві та в системі соціальних комунікацій.
The investigation of bioactive compounds in the Charentsi grape variety and its derived wines
Authors: Grigoryan Bella , Mikayelyan Mikayel
Published: November 2023

Background: Grapes contain thousands of chemical compounds, including sugars, organic acids, phenolic compounds, minerals, organic nitrogen, amino acids, and aromatic compounds.Objectives: The study investigates the possibility of producing high-quality red wines from the Charentsi grape variety and observes the extraction of   bioactive compounds formed during fermentation.Results: The organic acids in grapes and wine were also studied.  There were significant differences in the compounds mentioned above between wine samples based on the yeasts used. Our observations showed that the amount of tartaric acid in the Charentsi grape variety was 7.26 g/l, and after fermentation by using different yeasts in the wine samples, the content of tartaric acid was: BSC:103 2.06 g/l, AC-4: 1.79 g/l. The grape sample contained 3.01g/l malic acid, while the selections of wine BCS103 and AC-4 contained 2.01g/l and 3.00g/l, respectively. In the case of citric acid, the grape contained 0.5 g/l a, while the wine samples with BCS103 and AC-4 yeasts contained 0.52 g/l and 0.57 g/l respectively.The grape sample did not contain lactic acid or succinic acid. Wine samples were fermented by a variety of newly formed yeasts. In BCS103 yeast, these values were 1.89 g/l and 1.63 g/l, and 1.3 g/l and 1.61 g/l in AC-4.The values of anthocyanin and flavonoids in Charentsi grape variety are 2084.5 mg/kg and 8828.6 mg/kg, respectively. Wine samples contained high quantities of these compounds as well. The anthocyanin and flavonoids concentrations In BCS103, were 842.7 mg/l and 4898.22 mg/l, while they were 783.3 mg/l and 5025.5 mg/l in AC-4. The total phenolic compounds detected in the wine samples were 4957.9 mg/l and 5102.6 mg/l, in BCS103 and AC-4 respectively. According to the analysis, 37%-40% of anthocyanin and 55-56% of flavonoids were transferred to the wine.Conclusion: Charentsi grapes and wine are highly functional due to their high phenolic content and organic acids. These compounds are biologically active and influenced by the yeast strain used for wine fermentation.Keywords: grapes, red wine, phenolic compounds, organic acids, bioactive compounds
Low-density lipoprotein- cholesterol and its relation to epicardial fat volume in patients with type II diabetes mellitus
Authors: Hasan Asmaa A. , Ahmed Ghada M. S. , Abdel Hady Bassem M. , Ahmed Inass H. , El Saghier Entesar O. , El Sayed Marwa F. M. , Azel Lamiaa H. , Mohamed Marwa A, , Saleh Ola I. , Taha Randa S. E. , Raafat Mona A. , Abd Elaziz Ola H.
Published: November 2023

Objectives: This study aimed to compare EFV between diabetic and non-diabetic subjects in patients with clinical indications of CCTA and test the correlation between low-density lipoprotein-cholesterol (LDL-C) and EFV in type 2 diabetic (T2DM) patients.Methods: This study was conducted on 103 cases with chest pain and intermediate risk probability for CAD and was scheduled for CT coronary angiography divided into 47 diabetic patients and 56 non-diabetic patients. The total serum cholesterol, LDL-C, TG, and HDL-C levels were analyzed for each patient. MDCT to assess CACS and EFV for patients included in the study. Results: The results showed thatplasma total cholesterol, TG, and LDL-C were higher with decreased HDL in the diabetic patient. EFV was significantly higher in diabetic patients (54.5±14.9 vs 44.7±7.7, p <0.02). EFV had a significant  Linear correlation with plasma total cholesterol, LDL-C, and TG. In contrast, there is a significant negative correlation between EFV and HDL-c. EFV was significantly correlated with ca score (EFV was higher in diabetic patients with greater CAC score). Conclusion: EFV is rising in type II diabetic patients, especially those with high ca scores, and correlates well to their characteristic hyperlipidemia, especially LDL-C. So, all diabetic patients must be started on primary prevention against LDL-C to reduce the risk of atherosclerosis. Keywords: Type II DM, Epicardial fat volume, LDL-c.
Assumption-based argumentation for extended disjunctive logic programming and its relation to nonmonotonic reasoning
Authors: Wakaki Toshiko
Published: November 2023

The motivation of this study is that Reiter’s default theory as well as assumption-based argumentation frameworks corresponding to default theories have difficulties in handling disjunctive information, while a disjunctive default theory ( ddt) avoids them. This paper presents the semantic correspondence between generalized assumption-based argumentation (ABA) and extended disjunctive logic programming as well as the correspondence between ABA and nonmonotonic reasoning approaches such as disjunctive default logic and prioritized circumscription. To overcome the above-mentioned difficulties of ABA frameworks corresponding to default theories, we propose an assumption-based framework (ABF) translated from an extended disjunctive logic program (EDLP) since an EDLP can be translated into a ddt. Our ABF incorporates explicit negation and the connective of disjunction “|” to Heyninck and Arieli’s ABF induced by a disjunctive logic program. In this paper, first, we show how arguments are constructed from disjunctive rules in our proposed ABF. Then, we show the correspondence between answer sets of an EDLP P and stable extensions of the ABF translated from P with trivialization rules. After defining rationality postulates, we show answer sets of a consistent EDLP are captured by consistent stable extensions of the translated ABF with no trivialization rules. Finally, we show the correspondence between ABA and disjunctive default logic (resp. prioritized circumscription). The relation between ABA and possible model semantics of EDLPs is also discussed.
Tridimensional Structural Analysis of Tau Isoforms Generated by Intronic Retention
Authors: Domene-Serrano Indalo , Cuadros Raquel , Hernandez Felix , Avila Jesus , Santa-Maria Ismael
Published: November 2023

Background:

Tauopathies are a subset of neurodegenerative diseases characterized by abnormal tau inclusions. Recently, we have discovered a new, human specific, tau isoform termed W-tau that originates by intron 12 retention. Our preliminary data suggests this newly discovered W-tau isoform might prevent aberrant aggregation of other tau isoforms but is significantly downregulated in tauopathies such as Alzheimer's disease.

Objective:

To accurately predict, examine, and understand tau protein structure and the conformational basis for the neuroprotective role of W-tau.

Methods:

A tridimensional deep learning-based approach and in vitro polymerization assay was included to accurately predict, analyze, and understand tau protein structure and the conformational basis for the neuroprotective role of W-tau.

Results:

Our findings demonstrate: a) the predicted protein tridimensionality structure of the tau isoforms raised by intron retention and their comparison with the other tau isoforms; b) the interaction of W-tau peptide (from W-tau isoform) with other tau isoforms; c) the effect of W-tau peptide in the polymerization of those tau isoforms.

Conclusions:

This study supports the importance of the structure-function relationship on the neuroprotective behavior of W-tau inhibiting tau fibrillization in vitro.
A Procedural Checklist for Transurethral Resection of Bladder Tumors (TURBT) Enhances Operative Dictation and Assesses Surgeon Accuracy of Tumor Characteristic Predictions
Authors: Dave Priya , Patel Rutul D. , Desai Kush , Davila Jonathan , Sankin Alex
Published: November 2023

BACKGROUND:

A lack of standardization is pervasive in procedural application and reporting templates for TURBT with the use of a surgical checklist proposed as a means for quality improvement.

OBJECTIVE:

To introduce a TURBT checklist to assess surgeon prediction accuracy and the impact of standardized documentation on quality of resection and oncologic outcomes

METHODS:

Nine critical elements of a high-quality TURBT identified by literature review were incorporated into a prospectively implemented checklist for operative reports. The checklist included both visualized and predicted tumor characteristics. A retrospective single-institution analysis compared quality of dictation pre- and post-checklist implementation. Surgeon predictions were compared to final pathology reports to determine rates of concordance. Kaplan-Meier curves examined the association of checklist use with recurrence free survival (RFS).

RESULTS:

333 operative reports were included in this analysis, of which 107 (32.1%) were completed pre-checklist implementation. The average number of critical elements reported was 8.69 with checklist use compared to 4.99 without ( p < 0.001). There was no significant difference in RFS between the pre- and post-checklist cohorts (log-rank test p = 0.53). Surgeons were least and most accurate in predicting low grade tumor (43.5%) and absence of muscle invasion (96.6%), respectively.

CONCLUSIONS:

Incorporation of a TURBT surgical checklist improves operative dictation and quality of reporting but did not directly impact RFS. With quality of initial resection a proven correlate to recurrence rates, checklist implementation to improve surgical performance and long-term oncologic outcomes reveals an interesting area of exploration highlighting the need for more standardized methodology when performing these procedures.
Multi-objective cooperation optimization research on dynamic response and energy loss of high-speed solenoid valve for diesel engine injector
Authors: Yu Zhiqing , Zhao Jianhui , Wei Rongqiang
Published: November 2023

The dynamic response and operational reliability of high-speed solenoid valve (HSV) for diesel engine injector are the main indicators to measure their performance. At high-frequency, the eddy current energy and Joule energy generated by the HSV will be converted into heat, which has a significant impact on the service life of HSV. The optimization of HSV involves the interaction between energy loss and the dynamic response of HSV. To optimize the HSV dynamic response time considering energy loss, the HSV work process simulation model was established in this paper, and the model was verified based on armature lift experimental data. Without changing the structural parameters of the HSV, the four parameters of electroconductibility, spring stiffness, damping coefficient, and coil resistance were selected as the key parameters affecting the dynamic response and energy loss. The response surface models (RSMs) of opening response time, closing response time, eddy current energy and Joule energy of the HSV were constructed by using the smoothing spline-analysis of variance method. The multi-objective cooperation optimization of HSV under the interaction of dynamic response characteristics and energy loss was completed by using non-dominated sorting genetic algorithms. After optimization, the opening and closing response times of HSV were reduced by 15.1% and 16.6% respectively, while the eddy current energy and Joule energy were reduced by 5.2% and 48.4% respectively. In this paper, the dynamic response and energy loss were jointly optimized. The presented results provide theory instruction for multi-objective cooperative optimization of HSV.
Pre-employment transition and vocational rehabilitation services: Experiences in response to Vermont’s work-based learning program
Authors: Honeycutt Todd , Luhr Marlena , Harrison Emily , Sevak Purvi
Published: November 2023

BACKGROUND: State vocational rehabilitation (VR) agencies offer pre-employment transition services (pre-ETS) and other VR services to high school students, but the literature has not documented differences in pre-ETS use by individual characteristics or across individual services. OBJECTIVE: We describe variation in how high school students used services from the Vermont VR agency and how a demonstration program emphasizing work-based learning experiences affected that use. METHOD: The study uses a descriptive approach to explore patterns in youth’s pre-ETS and VR services and outcomes two years after enrolling in a demonstration program. It compares youth with access to demonstration services (the treatment group) to those using usual services (the control group). RESULTS: Among all control group youth, more than half only used pre-ETS during a 24-month period, while about one-quarter used VR services and the remainder used no services from the VR agency. In contrast, nearly all treatment group youth used some VR services, with a majority (59 percent) using both VR services and pre-ETS. Control group youth who used pre-ETS and VR services differed from those who did not use these services by gender, disability type, employment, and service receipt characteristics; treatment group youth had fewer such differences. Earnings outcomes did not vary in consistent or interpretable ways. CONCLUSION: The findings demonstrate how an intervention designed to promote work-based learning experiences increased pre-ETS and VR use and decreased subgroup differences in service utilization. VR administrators might consider collecting information on potentially eligible students to increase access to and use of services.
Autism and neurodiversity in the workplace: A scoping review of key trends, employer roles, interventions and supports
Authors: Wen Benjamin , van Rensburg Henriette , O’Neill Shirley , Attwood Tony
Published: November 2023

BACKGROUND: Autistic adults continue to experience high rates of unemployment and underemployment. OBJECTIVE: A scoping review was undertaken to: a) synthesise key findings in the literature regarding autism and employment from the employers’ perspective; b) examine trends in employer attitudes, theoretical frameworks and interventions; c) highlight gaps in the literature; and d) propose avenues for further research. METHODS: Literature published between January 1, 2009 and January 1, 2023 was examined using the following databases: CINAHL via Ebsco, Cochrane Library, EMBASE via Ovid SP, ERIC via Ebsco, Medline, PsycINFO via Ebsco, Scopus, Web of Science and ProQuest for dissertations and theses. RESULTS: The search identified 55 studies that met inclusion criteria. Selected articles were organised into the following themes: theoretical frameworks from the employer perspective, autism employment supports from the employer perspective and employer-specific interventions. CONCLUSION: This scoping review suggests that minimal research has been conducted on employer interventions that specifically target work environmental factors. The promotion of diversity in the workplace is an encouraging trend but this has not necessarily included the promotion of neurodiversity. Future research should include interventions to improve current and prospective employer knowledge and attitudes in not just hiring but supporting autistic persons in the workplace.
Adherence to the Mediterranean Diet among high-school pupils in the North Moroccan Rif region
Authors: El Mokhtari Oussama , Anzid Karim , Levy-Desroches Susan , Montero López María del Pilar , Cherkaoui Mohamed , Hilali Abderraouf
Published: November 2023

BACKGROUND:

The traditional Moroccan diet is typical of the Mediterranean diet (MD), but there have been few studies of the adherence of Moroccans adolescents to this diet and associated factors.

OBJECTIVE:

To evaluate MD adherence and its association with socioeconomic factors, nutritional status and dietary intake in a sample of secondary school pupils in the Rif region of Morocco.

METHODS:

In a cross-sectional study of a sample ( n = 302) of Moroccan Riffian adolescents (13–18 years) from three secondary schools, we measured adherence to MD with the Mediterranean Diet Quality Index for children and teenagers questionnaire (KIDMED). A score below 8 was qualified as poor to average adherence to MD, while an optimal adherence was defined as a score of 8 or higher. Bivariate analyses and a logistic regression model were used to examine associations between adherence to MD and socioeconomic factors, nutritional status and dietary intake.

RESULTS:

Only 14.9% of adolescents had an optimal adherence to the MD (score≥8 points), 72.8% had average adherence (score 4–7) and 12.3% had poor adherence to the MD (score≤3). The factors associated with optimal adherence to MD were female sex (OR 2.28; 95% CI 1.07 –4.85; p = 0.031), high monthly family income > 8000 MAD (OR 7.10; 95% CI 1.52 –33.1; p = 0.013) and living in an apartment (OR 3.85; 95% CI 1.43 –10.3; p = 0.007). For others factors such as nutritional status and dietary intake, no associations were observed.

CONCLUSION:

We found a low level of adherence to the MD among adolescents in the Rif region, supporting the hypothesis that the dietary pattern of these Moroccan adolescents is in a transitional state characterised by a shift away from the traditional MD. The findings of this study suggest that interventions to optimize MD adherence should target boys, shared residences and lower income families.
Targeting Alzheimer's disease hallmarks with the Nrf2 activator Isoeugenol
Authors: Silva Ana , Silva Sónia , Macedo Jéssica , Moreira Patrícia , Baptista Diana , Bicker Joana , Fortuna Ana , Liberal Joana , Rodrigues Beatriz , Resende Rosa , Santos Armanda E. , Pereira Cláudia , Cruz Maria Teresa
Published: November 2023

Alzheimer´s disease is a neurodegenerative disease and the most common cause of dementia with no cure or treatment. Therefore, the investigation to find a disease-modifying therapeutic is crucial. From a pathophysiological point of view, AD is characterized by the loss of homeostatic functions that control redox and energy metabolism, neuroinflammation, and proteostasis. The transcription factor nuclear factor erythroid 2–related factor 2 (Nrf2) is a master controller of these functions and, in the past decades, recent reports have shown that its overall activity is compromised in AD. Thus, Nrf2 has been considered an attractive molecular target for AD therapeutic research. Most pharmacological Nrf2 activators are small electrophilic molecules that react with cysteine residues present in Kelch-like ECH-Associating protein 1 (Keap1), thereby inducing Nrf2 release and further nuclear translocation and activation. Accordingly, low molecular weight skin allergens, such as dimethyl fumarate, currently used to treat the relapsing forms of multiple sclerosis and with positive results in preventing spatial memory impairments and hippocampal neurodegeneration in rats, are able to activate Nrf2. This activation is well explained by their direct reactivity towards key cysteine residues of Keap1, leading to its dissociation from Nrf2, which in turn is translocated to the nucleus inducing the transcription of over 250 protective genes. Hence, we conducted a ground-breaking study where the potential of Isoeugenol, a skin allergen with electrophilic properties, to activate Nrf2 and revert some AD hallmarks, was investigated. This work was conducted in vitro (in mice microglia cells exposed to LPS and neuronal cells overexpressing the human APP with Swedish mutation, N2a-APPswe) and in vivo (in the AD double transgenic mice, APP/PS1, intranasally administered with Isoeugenol), at an early (6-month-old animals) and late (11-month-old animals) AD stage.

Overall, the results showed that Isoeugenol exhibit a good pharmacokinetic and pharmacodynamic profile. Isoeugenol activates Nrf2 and displays antioxidant and anti-inflammatory effects and reduced the levels of Aβ peptides in in vitro and in vivo models of AD. In addition, its positive effect on metabolism was also demonstrated in vivo, as it reduced the triglyceride and LDL cholesterol levels in treated AD mice. Importantly, Isoeugenol improved the memory deficits observed in APP/PS1 mice, which was more evident in older animals (11-month-old), reinforcing its potential in ameliorating AD hallmarks, even at a late stage.
DAMPAK KOMPETENSI KEPRIBADIAN GURU PENDIDIKAN AGAMA ISLAM TERHADAP SELF REGULATED LEARNING SISWA
Authors: Riany Helifsia , Muslimah Muslimah , Khalfiah Yuliani
Published: November 2023

This study aims to describe the personality competencies of PAI teachers at SMA PGRI 2 Sampit, Kotawaringin Timur district. In addition, to describe the impact of personality competence of PAI teachers on self-regulated learning of students at SMA PGRI 2 Sampit, East Kotawaringin district. This research method uses qualitative which produces descriptive data to understand a phenomenon naturally. The results of the study are that the personality competencies of PAI teachers at SMA PGRI 2 Sampit are in accordance with personality competency indicators, including a solid and stable personality, mature personality, wise and wise, authoritative and have noble character, PAI teachers have carried it out well. Then the impact of the personality competence of the PAI teacher on students' self-regulated learning is that students can control their behavior in learning, have the independence to determine and assess the learning strategies needed, be disciplined, be responsible. In addition, students' motivation and enthusiasm increased and students did not feel bored and reluctant to participate in learning activities.
INTERNALISASI KARAKTER ISLAMI BERBASIS PROJEK PENGUATAN PROFIL PELAJAR PANCASILA
Authors: Mahmudah Nashikhatun , Kurnianto Rido , Syam Aldo Redho , Arifin Syamsul
Published: November 2023

Penelitian ini bertujuan untuk mengetahui proses internalisasi nilai profil pelajar Pancasila dalam membentuk karakter Islami peserta didik, hasil internalisasi nilai profil pelajar Pancasila dalam membentuk karakter Islami peserta didik, serta faktor pendukung dan faktor penghambat internalisasi nilai profil pelajar Pancasila dalam membentuk karakter Islami peserta didik di SMPN1 Ponorogo. Penelitian ini dilakukan menggunakan pendekatan kualitatif dengan teknik pengumpulan data yaitu observasi, wawancara, dan dokumentasi. Selanjutnya, dilakukan penyajian data dengan menggunakan metode deskriptif berupa teks naratif yang diperoleh dari subjek yang diamati, yaitu warga sekolah, meliputi: Kepala Sekolah, Waka Kurikulum, Guru Penggerak, dan Peserta didik kelas VII. Penelitian ini dilaksanakan di Sekolah Menengah Pertama Negeri 1 Ponorogo.Adapun hasil penelitian di SMPN 1 Ponorogo diantaranya sebagai berikut: 1) Proses internalisasi nilai profil pelajar Pancasila dalam pembentukan karakter Islami pada peserta didik yang dilakukan melalui tahap transformasi atau penyaluran nilai-nilai berupa akhlak terpuji, dengan pemberian arahan dan nasehat tentang mana nilai yang baik dan buruk; tahap transaksi nilai, dengan melakukan komunikasi dua arah antara peserta didik dengan pendidik  untuk meyakinkan peserta didik; tahap transinternalisasi nilai, dengan adanya pembiasaan, kegiatan keagamaan dan pembelajaran berbasis proyek (P5). Strategi yang digunakan adalah keteladanan, pembiasaan, monitoring, reward dan punishment. 2) Hasil internalisasi nilai profil pelajar pancasila dalam pembentukan karakter Islami pada peserta didik cukup signifikan, peserta didik   terbangun karakter pada dirinya berupa karakter religius, mandiri, peduli lingkungan dan peduli sosial, serta tanggung jawab. 3) Faktor pendukung internalisasi nilai profil pelajar Pancasila dalam pembentukan  karakter Islami pada peserta didik  diantaranya adalah sistem sekolah, terjalinnya kerja sama yang baik antar pendidik, lingkungan sekolah dan sarana prasarana yang memadai, adanya dorongan dari wali dari peserta didik serta komite sekolah. Sedangkan faktor penghambatnya adalah beragamnya keadaan peserta didik serta kurangnya keseimbangan antara lingkungan sekolah dan rumah.
Strategi Pemasaran Keripik Tempe Ceria di Desa Sumber Mulya Kecamatan Simpang Raya Kabupaten Banggai
Authors: Rosilawati Ratmi , Wijayanti Dwi , Farma Rengga Lupita
Published: November 2023

Abstract: With the advancement of time and creative innovation from humans, tempeh is no longer just a side dish to accompany rice, but can be used as a practical and ready-to-eat snack, namely tempeh chips. The aim of this research is to determine the marketing strategy which includes product, price, promotion and distribution of cheerful tempeh chips in Sumber Mulya Village, Simpang Raya District and its surroundings. This research was carried out at Usaha Ceria, Sumber Mulya Village, Simpang Raya District, Banggai Regency from May to June 2023. The number of samples used was 12 people. The data analysis used is SWOT analysis. The research results show that the product strategy for cheerful tempe chips is that the product is always available, the product has product attributes, brands and labels, and has an affordable price. The promotional strategy for cheerful tempe chips is personal sales promotion, in other words word of mouth promotion. Apart from that, promotions are also carried out through social media. The distribution strategy for cheerful tempe chips is from producers directly to consumers and from producers to distributors and distributors to consumers. Cheerful tempeh chips products are distributed to several shops/supermarkets inside and outside Banggai Regency. Marketing of cheerful tempe chips is in quadrant I supporting an aggressive growth policy (Growth Oriented Strategy).
Cultural communication based on image processing in multimedia network environment
Authors: Chen Ruolei , Chen Xujia
Published: November 2023

In the process of uploading pictures of cultural products under the multimedia network environment, image processing technology is indispensable for page production and picture design, and image processing plays an indispensable role. Purpose: The use of image processing technology enriches the means of cultural communication, and also improves the visual effect and dissemination rate of cultural communication to a certain extent, and produces the effect of deepening people’s hearts. Methods: This paper firstly focuses on the problems and development trends in cultural communication, and uses image processing technology in the multimedia network environment to analyse the effects of cultural communication, and secondly focuses on the application of multimedia network and image processing in cultural communication. Finally, the four-degree evaluation method is used to evaluate the effect of cultural communication. Results: The final results show that with the use of image processing techniques, the rate of cultural dissemination in various cultural fields can reach 50% to 75%. Conclusion: The research on cultural communication based on image processing can deepen the understanding of cultural communication in the multimedia network environment, expand the application of image processing technology in the field of cultural communication, analyse the role and influence of images in cultural communication, and promote the cross-fertilization of cultural communication and image processing, which is of great practical application and academic value.
Pineal Bölge Tümörleri: Tek Merkez Deneyimi
Authors: ÖZŞEN Mine , TOLUNAY Sahsine , YILMAZLAR Selçuk , BEKAR Ahmet
Published: November 2023

Yetişkinlerde tüm intrakraniyal tümörlerin %1'inden azını, pediatrik grupta ise %3-11'ini oluşturan pineal bölge tümörleri oldukça heterojen bir gruptur. Bölgenin tümör ve lezyonlarını genel bir başlık altında toplayarak dört gruba ayırmak mümkündür. Bunlar germ hücreleri tümörler, pineal parankimal tümörler ve glioma gibi komşu yapılardan kaynaklanan tümörler ve diğerleri şeklindedir. Çalışmamıza merkezimizde 2005-2020 yılları arasında opere edilmiş tüm pineal bölge tümörleri dahil edildi. Olguların demografik bilgileri, ön tanı, tümör çapı, klinik ve radyolojik bilgileri, sağkalım durumu, nüks varlığı ve son kontrol tarihleri hastane veritabanından ve patoloji raporlarından elde edildi. Çalışmaya dahil edilen olgulara ait hematoksilen eozin boyalı preparatlar ile mevcutsa immünohistokimyasal ve histokimyasal çalışma yapılan preparatlar histopatolojik tanı ve grade açısından yeniden değerlendirildi. Olguların histopatolojik değerlendirmesinde 6 (%22,2) olgu menengioma, 5 (%18,5) olgu pineoblastoma, 4 (%14,8) olgu pineositoma, 2 (%7,4) olgu pineal bölgenin papiller tümörü, 2 (%7,4) olgu orta derecede farklılaşma gösteren pineal parankimal tümör, 2 (%7,4) olgu glioblastoma, 2 (%7,4) olgu germ hücreli tümör (germinoma ve matür kistik teratoma), 1 (%3,7) olgu oligodenrioglioma, 1 (%3,7) olgu pilositik astrositoma, 1 (%3,7) olgu metastatik karsinoma ve 1 (%3,7) olgu gliozis ve hemosiderin pigment birikimi şeklinde tanı aldı. Pineal bölge çeşitli benign ve malign natürde tümörlerin gözlenebildiği özel bir lokalizasyondur. Histopatolojik değerlendirme yapılmadan önce mutlaka olgunun klinik, laboratuvar ve radyolojik verilerine hakim olunmalıdır. Mikroskobik değerlendirme bölgenin sahip olduğu geniş tanı yelpazesi göz önünde bulundurularak, yapılmalı ve gerekli durumlarda immünohistokimyasal ve histokimyasal çalışmalardan yardım alınmalıdır.