bluuebunny/crossref_metadata_2025 huggingface dataset:
Tinospora cordifolia, a reservoir plant for therapeutic applications: A Review
Authors: Akash Sable , S.L. Jadhav , S.C. Kamble
Published: September 2022

Ayurvedic Unani Siddha and Homeopathy (AYUSH) are the traditional system of medicines which have been practice in a great amount. Tinospora cordifolia belongs to woodely climbing shrub which widely distributed throughout India, China and Africa etc. Its common name is Amrita and Gudachi belongs to family Menispermaceae. The root, stem and leaves of plants have main pharmaceutical significance various phyto active compounds it involves alkaloids steroids glycoside lactones polysaccharides are present in different parts of the Tinospora cordifolia.
A Overview on Nanoemulsion
Authors: Ankush R Doiphode , S. L. Patwekar , Namdev Guhade , Gole Vaishnavi , Rode Ashwini , Shaikh Suleman
Published: September 2022

Nanoemulsions are colloidal emulsions made up of two immiscible liquids, one of which is scattered and the other continuous. Nanoemulsions are two types W/O and O/W. Nanoemulsion are size varies from 20 to 200nm. Nanoemulsions are thermodynamically stable. Emulsifiers are stabilised nanoemulsion. There are two types of emulsifiers: one is hydrophilic and the other is lipophilic. Nanoemulsion is widely used in food industry, beverages, agriculture, bio-pharmaceutical, dairy products. Nanoemulsion widely prepared by using high energy or brute force comprising ultra sonication and ultra high pressure homogenizer and low energy or persuasion method compressing both phase inversion composition (PIC) and the phase inversion temperature (PIT). Newly a developed method used as preparation of nanoemulsion bubble bursting, micro- fluidization and evaporative ripening. The aim of review a article focusing on to preparation method characterization application of nanoemulsion.
Preparation and Evaluation of Sustained Release Hydrogel Alginate Beads of Meclizine Hydrochloride
Authors: Deshmukh Neha
Published: September 2022

Oral controlled drug delivery systems represent the foremost widespread kind of sustained drug delivery systems for the plain blessings of oral route of drug administration. Suchsystemsrelease the drug with constant or variable unleash rates. The oral controlled releasesystems show a typical pattern of drug unleash within which the drug concentration is maintained inthe therapeutic window for a chronic amount of your time (sustained release), thereby guaranteeingsustained therapeutic action. They are used as single dosage form. Present work involvespreparation and analysis of sustained release beads of beads of Meclizine Hydrochloride using Sodium alginate as natural polymer as well as Hydroxyl Propyl Methyl Cellulose K15, Sodium CMC. The technique employed for preparation of beads of the drug is ionotropic gelation.
The mRNA Vaccine Heralds a New Era in Vaccinology
Authors: Shinde Ketaki , Bendre Sonam , Kale Niraj , Gilda Suhit
Published: September 2022

Vaccination has had a significant impact on infectious diseases control. However, there are still a number of infectious diseases for which an effective vaccine has yet to be developed. There has been a lot of interest in RNA-based technologies for the creation of therapeutic vaccines over the last two decades. The adaptability of mRNA vaccines, as well as their potential to trigger cellular and humoral responses, are among their benefits. Furthermore, because of their intricate interaction with pattern recognition receptors (PRRs), mRNAs have inherent adjuvant qualities. This identification can be advantageous in terms of stimulating antigen-presenting cells (APCs) or harmful in terms of limiting mRNA translation indirectly. We highlight how numerous innate response mechanisms are triggered by mRNA molecules, and how each element, from the 5' cap to the poly-A tail, interferes with innate/adaptive immune responses. mRNA vaccines have the ability to be developed quickly and to be a strong tool in the fight against infectious illnesses. This article provides a thorough overview of mRNA vaccines, including recommendations for future mRNA vaccine development, as well as safety concerns and personalised vaccines. We focused on mRNA delivery and immunological activation, both which have important role for successful mRNA vaccination.
A Review: Health Benefits of Herbal Plants in Nutraceuticals
Authors: Anamika Anamika , Chauhan Vandita , Nautiyal Anuj
Published: September 2022

The term "Nutraceutical" comes from "nutrition" and "pharmaceutical". It is defined as a diet or part of a diet that provides health benefits of nutritious foods and helps prevent many diseases. Lifestyles have changed dramatically in the last 50 years as a result of urbanization, industrialization speed, and rapid change. These things have changed people's habits and forced them to eat fast, junk food. These habits directly affect our aspect of healthy eating and gradually reduce the amount and quality of nutrients. As a result of these changed eating habits, the population has increased the incidence of malnutrition, dementia and degenerative diseases. In recent years, people have become more concerned about health and health care. Nutraceuticals play an important role in boosting the immune system without damaging the body's natural immune system. Nutraceuticals are found in dietary supplements that offer additional health benefits also called medical diets, designer foods, active foods, and dietary supplements. Active foods are used to enhance certain bodily functions to prevent or treat infections. The medicinal plant contains many types of active phytochemicals that have therapeutic properties that address various health problems. This review explores the information available in the literature regarding health benefits of nutraceuticals and many other herbal plants. So here, an attempt is made to highlights the significance or importance of nutraceuticals and herbal plants with respect to health diseases and many other problems related to health. Therefore, the future nutraceutical program focuses on specific diagnostic models, clinical studies in humans, understanding the exact mechanism of action that is useful in the prevention and treatment of diseases. Nutraceuticals has demonstrated health benefits and immunity which should be taken as recommended.
What are the monetary returns of investing in programs that reduce demand for illicit drugs?
Authors: Voce Alexandra , Sullivan Tom
Published: September 2022

This study reviews benefit–cost analyses of programs designed to reduce demand for illicit drugs. Data were synthesised from 67 benefit–cost analyses of prevention, law enforcement and treatment programs. Eighty percent of the 70 separate benefit–cost ratios exceeded 1.0, indicating that savings outweighed costs among most programs reviewed. Benefit–cost ratios ranged from −18.20 to 63.32, varying substantially for different program types and populations. On average, demand reduction programs produced a return on investment of $5.40 for every dollar spent. These findings suggest demand reduction programs are generally economical.
مدى إلمام المكتبين في السودان بحقوق الملكية الفكرية دراسة حالة : المكتبات الجامعية ولاية الخرطوم
Authors: القدال حسام الدين عوض الله احمد    
Published: September 2022

المستخلص

      تعتبر حقوق الملكية الفكرية من المصطلحات القديمة الحديثة حيث كثر الحديث عنها في الآونة الأخيرة وأصبحت ملازمة لكل المجالات الإنسانية لاسيما مجال المعلومات والمكتبات والذي من مهامه إتاحة المعلومات للمستفيدين من خلال إجراءات تخزين وحفظ واسترجاع المعلومات والعديد من الخدمات، ولم تبرز مشكلة حقوق الملكية الفكرية بصورة مزمنة مع المكتبات التقليدية وذلك لان المكتبات كانت تقتني نسخا من المواد المكتبية اقتناء حقيقيا، وتكون مجموعاتها وتقدمها للمستفيدين من خلال مجموعة من الإجراءات والخدمات، ولكن مع التطورات التقنية وسيطرة البيئة الرقمية علي حياة الناس اليومية والاتجاه إلي المكتبات الرقمية برزت العديد من المشكلات في نظر المكتبين، حيث أصبحت إتاحة المعلومات تخضع لشروط المزودين، وصارت المكتبات بدلا من أن تقتني المواد المكتبية تؤجرها من خلال اتفاقيات الترخيص المعقدة التي  تتحكم في طريقة تقديم الخدمات وعدد المستخدمين (المستفيدين) وحجم الاستخدام ، وهذا بدوره قد يخلق كثير من المشكلات القانونية للمكتبات أو أن تقع هذه المكتبات ضحية لاتفاقيات ترخيص ظالمة لا تمكنها من أداء دورها الخدمي والاجتماعي لجمهورها من المستفيدين.

وتم التركز في هذه الدراسة في شقها النظري علي مفهوم الملكية الفكرية وتفصيل حق المؤلف والحقوق المجاورة وقضية الملكية الفكرية في المكتبات الرقمية في اما الشق الميداني فركزت الدراسة علي  التعرف علي مدي إلمام المكتبين بحقوق الملكية الفكرية من خلال استبيان للعاملين في المكتبات الجامعية في ولاية الخرطوم وتم تحليل هذا الاستبيان ببرنامج SPSS .
تصميم مقياس لقياس التربية البيئية لدى طلبة المرحلتين الثانوية والجامعية
Authors: الصديق فاطمة محمد الخير
Published: September 2022

توالى تخريب الإنسان للبيئة منذ عقود طويلة وظهر أثر هذا التخريب في صحة البشر وحياتهم اليومية، وأثر التغير المناخي على أنظمة بيئية عدة، فغمرت المياه المناطق الساحلية في عدد من بقاع العالم مما اثر سلبا في حياة السكان هناك، وتنوعت المشاكل البيئية بتنوع أشكال التلوث البيئي والتعامل غير المرشد مع الموارد البيئية. إن هذا النتاج البيئي إنما نتج من سلوك الإنسان والذي يجب تحسينه بأساليب التربية البيئية وخاصة لدى النشء الذين سيرثون هذه الأرض. و السودان كغيره من الدول يعاني من بعض المشاكل البيئية كالتصحر وتدهور بعض الموارد الطبيعية وظهور بعض مظاهر التلوث البيئي والتي لن ينجح في التصدي لها والعمل على حلها إلا بتأهيله لأبنائه – خاصة الطلبة منهم – في هذا المجال، وذلك بتزويدهم بالمعارف البيئية المتكاملة، وغرس الانفعالات الوجدانية الملائمة تجاه مشكلات البيئة في أنفسهم، وتزويدهم بأساليب السلوك البيئي الحميد، كل ذلك يتم من خلال أساليب التربية البيئية الطيبة والتي يمكن أن تقوم بها العديد من مؤسسات المجتمع. لذا رأت الباحثة أن تصمم مقياسا لمعرفة كنه التربية البيئية التي يتلقاها الطلبة في المرحلتين الثانوية والجامعية الأمر الذي تراه يشكل تشخيصا لمعرفة مدى ما يتلقاه هؤلاء من تربية بيئية، فالتشخيص هو المنطلق الأول للتصحيح أو الارتقاء
القضاة في كتاب النشوار للتنوخي
Authors: الدوسري محمد بن صقر
Published: September 2022

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التوزيع الجغرافي والتأثير الايجابي لنشاط الصندوق السعودي للتنمية في تمويل مشروعات التنمية المستدامة في السودان
Authors: مصطفى  عباس الطيب بابكر
Published: September 2022

تأتي دراسة التوزيع الجغرافي والتأثير الايجابي لنشاط الصندوق السعودية للتنمية في إطار التعرف على مشروعات التنمية في السودان والفوائد الاقتصادية والاجتماعية لهذه المشروعات على المجتمعات المحلية بالإضافة إلى بيان دور المؤسسات التمويلية الاقليمية في تمويل مشر وعات التنمية المستدامة في السودان ممثلة في الصندوق السعودي للتنمية. 

ولتحقيق الاهداف المرجوة من الدراسة اعتمدت الدراسة في جمع بياناتها وتحليلها على المنهج الاستقرائي والمنهج التاريخي المقارن والمنهج الوصفي، وذلك على البيانات المتوفرة في التقارير السنوية للصندوق السعودي للتنمية خلال الفترة ما بين عامي 5791- 8152م، وعلى الدراسة الميدانية للمشروعات التنموية في السودان، إذ تم إجراء المقابلات الشخصية مع أدارات المشروعات الممولة في السودان، وكذلك الدراسة الميدانية لقرى أمري والمناصير والحماداب الحديثة في منطقة مش روع سد مروي بالسودان كمثال لهذه المشروعات.

أظهرت نتائج الدراسة التوزيع الجغرافي للمشاريع التنموية في التأثير الايجابي للمشاريع التنموية التي ساهم الصندو ق السعودية للتنمية في السودان وبخاصة في قطاع الطاقة وحصاد مياه الشرب، حيث عادت مشاريع سد مروي وتعلية خزان الروصيرص وسد عطبرة وستيت بالعديد من الفوائد الاقتصادية لسكان هذه المناطق مثل زيادة الرقعة الزراعية وتوفير مياه الر ي وتوفير فرص العمل، وتوفر خدمات مياه الشرب والكهرباء والتعليم والصحة. وأوصت الدراسة بأهمية المسح الجغرافي للموارد الطبيعية التي يتميز بها السودان لدعم صناع القرار في التخطيط للمشاريع التنموية التي تزيد من الفوائد الاقتصادية والاجتماعية للسكان والدخل القومي على حد سواء مع ضرورة مشاركة المجتمع المحلي ومشورة الخبراء في ذلك.
Cartesian Coordinates in Two-Dimensional Bone Histology Images for Quaternary Bone Remodelling Research
Authors: Miszkiewicz Justyna J. , Louys Julien , Mahoney Patrick
Published: September 2022

Palaeohistologists who work with well-preserved cortical bone can examine two-dimensional (2D) histology images for quantitative parameters of secondary osteons and Haversian canals to reconstruct past bone remodelling. Standard techniques in this space include area measurements and counts of histology components recorded from an image. The ‘point-count’ technique involves counting all the items (e.g., secondary osteons, osteocyte lacunae) of interest per image area. The open access image analysis software ImageJ/FIJI facilitates this technique in a user-friendly way. Raw data points are captured and can be saved in a spreadsheet. Aside from the total number of counts, the software also issues Cartesian (XY) coordinates locating each counted point. These XY coordinates are typically neglected within palaeohistological approaches due their assumed irrelevance to research questions of bone remodelling significance. We provide a short evaluation of XY coordinates captured by ImageJ/FIJI from 2D bone histology images, and a protocol for a simple calculation of XY distances that follow the path of point counting. We focus on osteocyte lacunae which serve as a proxy for osteoblast-osteocyte conversion in live bone by replicating the protocol on a bone sample from a human Medieval English individual. We discuss the potential of XY coordinates for reconstructing the proximity of osteocyte lacunae and related bone remodelling activity through exchange of nutrients by neighbouring cells. We recommend palaeohistologists report XY coordinate data in their results to ensure better vertebrate palaeobiology characterisation.
Analisis Penerapan Akuntansi Persediaan Barang Habis Pakai Pada Badan Kepegawaian dan Pengembangan Sumber Daya Manusia di Kabupaten Minahasa
Authors: Tombuku Tesalonika , Manaroinsong Johny
Published: September 2022

Penelitian bertujuan untuk mengetahui penerapan akuntansi persediaan dengan standar yang berlaku, yang diterapkan pada Badan Kepegawaian dan Pengembangan Sumber Manusia di Kabupaten Minahasa. Pengakuan persediaan, pengukuran persediaan, dan pengungkapan persediaan merupakan bagian dari akuntansi persediaan yang di maksudkan. Standar yang di maksud dalam penelitian ini ialah Pernyataan Standar Akuntansi Pemerintahan Berbasis Akrual Nomor 05 tentang akuntansi persediaan yang tertuang dalam Peraturan Pemerintah Nomor 71 Tahun 2010. Teknik pengumpulan data yang di gunakan ialah dokumentasi. Dokumentasi merupakan pengumpulan data-data yang mendukung penelitian ini, seperti bukti transaksi, jurnal, hingga laporan keuangan Badan Kepegawaian dan Pengembangan Sumber Daya Manusia tahun anggaran 2019. Analisis deskriptif kualitatif ialah teknik yang di gunakan untuk menganalisa data yang ada. Hasil dari penelitian ialah akuntansi persediaan pada Badan Kepegawaian dan Pengembangan Sumber Daya Manusia di Kabupaten Minahasa sebagian besar telah mengikuti peraturan dan standar yang di tetapkan dan pengakuan persediaan dengan menggunakan pendekatan beban belum menggunakan basis akrual.
Analisis Penerapan Tax Amnesty jilid I di Kantor Pelayanan Pajak Pratama Manado
Authors: Pulu Fumiko , Moroki Florence , Tala Olifia
Published: September 2022

Penelitian ini dilakukan agar mengetahui penerapan yang telah diterapkan serta dilakukan oleh kantor pelayanan pajak pratama manado. Pelaksanaan penelitian berlangsung di Kantor Pelayanan Pajak Pratama Manado. Metode yang digunakan ialah menggunakan deskriptif. Data yang diperoleh merupakan wawacara serta dokumentasi. Jenis data yang digunakan peneliti ialah data kualitatif. Sumber data penelitian ialah merupakan data sekunder dan data primer dari kantor pelayanan pajak pratama manado. Hasil dari penelitian ini menunjukkan bahwa penerapan Tax Amnesty jilid I pada Kantor Pelayanan Pajak Pratama Manado telah sesuai dengan Undang-undang Nomor 11 Tahun 2016 serta mencapai target yang lebih sehingga mendapatkan apresiasi yang baik dari pemerintah.

Kata Kunci: Pajak, Tax Amnesty jilid I, Penerapan Tax Amnesty
Pengaruh Free Cash Flow dan Investment Opportunity Set Terhadap Dividen Payout Ratio Pada Perusahaan Manufaktur Yang Terdaftar di BEI tahun 2017-2020
Authors: Mashanafi Bagus S , Pontoh Jones , Marunduh Andrew
Published: September 2022

Penelitian ini bertujuan untuk mengetahui apakah Free Cash Flow dan Investment Opportunity Set terhadap Dividend Payout Ratio pada Perusahaan Manufaktur yang Terdaftar di BEI Tahun 2017-2020. Metode penelitian dalam skripsi ini adalah analisis statistik deskriptif, uji chow, uji hausman, dan uji hipotesis. jumlah sampel penelitian ini sebanyak 180 dengan menggunakan purposive sampling diperoleh 10 perusahaan selama 4 tahun. Berdasarkan hasil analisis data dengan menggunakan uji parsial (t), free cash flow berpengaruh signifikan terhadap dividend payout ratio yang ditunjukkan dengan t hitung sebesar -0,30 dan nilai signifikan 0,00 sehingga hipotesis alternatif pertama diterima. Variabel investment opportunity set berpengaruh signifikan terhadap dividend payout ratio ditunjukkan dengan t hitung 0.87 dengan nilai signifikan 0,04 (lebih kecil dari 0,05) sehingga alternatif kedua diterima. Sedangkan secara simultan (f), Free Cash Flow dan Investment Opportunity Set berpengaruh terhadap Dividen Payout Ratio adalah sebesar 0,045 < 0,05 dan nilai F hitung 3,384 > F tabel 3,24.
Pengaruh Kesadaran Wajib Pajak, Pengetahuan Wajib Pajak Dan Tingkat Penghasilan Terhadap Kepatuhan Dalam Membayar Pajak Bumi Dan Bangunan (PBB) Di Kecamatan Tompaso
Authors: Badar Glori , Kantohe Meidy Santje Selvy
Published: September 2022

Penelitian ini bertujuan untuk mengetahui Pengaruh Kesadaran Wajib Pajak, Pengetahuan Wajib Pajak Dan Tingkat Penghasilan terhadap Kepatuhan Dalam Membayar Pajak Bumi Dan Bangunan (PBB) Di Kecamatan Tompaso. Populasi dalam penelitian ini adalah wajib pajak bumi dan bangunan yang terdapat di wilayah kecamatan Tompaso. Populasi berjumlah 2013. Penentuan ukuran sampel dilakukan dengan menggunakan rumus slovin sehingga diperoleh sampel dengan jumlah 95 responden. Data penelitian ini dikumpulkan menggunakan kuesioner yang kemudian diolah dengan mengggunakan analisis regresi linear berganda. Hasil penelitian secara parsial menunjukan bahwa kesadaran wajib pajak, pengetahuan dan tingkat penghasilan berpengaruh secara positif dan signifikan terhadap kepatuhan dalam membayar pajak bumi dan bangunan. Hasil uji simultan (berganda) menyatakan bahwa kesadaran wajib pajak, pengetahuan wajb pajak dan tingkat penghasilan berpengaruh secara bersama-sama terhadap kepatuhan wajib pajak bumi dan bangunan.
Formulation and characterization of floating biphasic tablet consisting of cefdinir nanosuspension
Authors: Al-Mahmood Asia Abed , Alhammid Shaimaa N. Abd
Published: September 2022

Cefdinir (Cef) is a third-generation cephalosporin antibacterial agent with an extended spectrum and low solubility and permeability. In this study, cefdinir was prepared as nanosuspension and lyophilized to powder.  The lyophilized cefdinir was further processed to develop a bilayer tablet. By utilizing the  bilayer approach, the first therapeutic action is impacted by the immediate part's rapid disintegration and a prolonged release from the floating part is achieved.  Floating system ensures a recognized extended-release in the gastric medium and avoids the numerous daily dosages. Different polymers were utilized with effervescent materials in different concentrations. The method employed in preparing tablets  is direct compression. Every formulation undergoes through standard pre and post-compression floating tablet characteristics with unique results that allow for further comparison between various formulations and increase our understanding of the makeup of medications, polymers, additives, and preparation technique. The formula NFT8 was selected as the best formulation design. It contains (HPMC K4M 400 mg, Carbapol940 50 mg, sodium bicarbonate 100 mg, and citric acid 75 mg) and provided efficient floating characteristics for more than 24 hr as revealed by in vitro dissolution release.
Antigastric parietal cell antibody as a screening test for Autoimmune gastritis in Egyptian children and adolescents with juvenile autoimmune thyroid disease and those with type 1 diabetes, single center experience
Authors: Eskander Ayman Emil , Subhy Nancy Samir , Abdelfattah Walaa , Shamma Radwa A.
Published: September 2022

Purpose: The diagnosis of pediatric autoimmune gastritis (AIG) is critical due to the poor outcome and risk of malignancy. Therefore, we evaluated the prevalence of autoimmune gastritis in children with autoimmune thyroid disease (ATD) and type 1 diabetes mellitus (T1D), using parietal cell antibody (PCA) to identify its use as a screening test. Methods: PCA was measured in 90 patients; 45 patients with ATD (Hashimoto Thyroiditis and Graves' Disease) and 45 patients with T1D. Their ages ranged from 5 to 18 years. Hemoglobin, ferritin, and HbA1c (in diabetic patients) were measured.  Results: PCA demonstrated a statistically significant difference between the two groups of patients with a p-value (0.024). The mean value of  PCA  in patients with T1D  was 196.45, while it reached 148.58 in patients with ATD, with a p-value (0.003). Thirty-one (68.9%) and twelve (26.7%) of patients with T1D had high (30-200) and extremely high (> 200) values of PCA, respectively, compared to twenty-six (57.8%) and eight (17.8%) of patients with ATD who had high (30-200) and extremely high (> 200) values of PCA, respectively. Seven (87.5%) of patients with ATD with extremely high PCA( above 200) also had normocytic anemia.
Using Elisa and nested PCR for detection of the toxoplasmosis in milk and the influence of infection and some factors on milk composition in the Iraqi local and Shami goats
Authors: Madi Entesar Hussain , Al-Samarai Firas Rashad
Published: September 2022

This study concluded detection of Toxoplasma gondii in milk, immunologically by using Elisa and nested PCR)nPCR (based on B1 gene, also to investigate the effect of toxoplasmosis, parity, breed and flock on some milk composition in the Iraqi local and Shami goats in the middle of Iraq. A total of 80 milk samples of the lactating goats were collected. Results of this study showed the prevalence of Toxoplasmosis was 21.25% and 28.75% by Elisa and nPCR respectively without significant differences. The sensitivity of Elisa was a low (30.43%) whereas the specificity was a high (82.45%). The degree of agreement estimated by Kappa coefficient revealed a slight agreement (0.14) between two methods. The results indicated that goats infected with toxoplasmosis have significantly (P<0.05) higher in protein and lactose percentage whereas the effect was not significant for each of fat, SNF and pH. On the other hand, the effect of parity was significant (P<0.05) on fat, protein, lactose, solid nonfat and non-effect on PH. As well as effect of breed and flock was significant (P<0.05) on protein, lactose and solid nonfat without significant effect on fat and PH.
Assessment of nutrition and dietary pattern in IBD patients
Authors: Khalidy Nawal Al , Jasim Zina Khalaf , Hasan Abeer Adnan
Published: September 2022

Background: Inflammatory bowel diseases are chronic debilitating illnesses, nearly 3,9 million females and nearly 3,0 million males are living with IBD worldwide and the number of prevalent cases is on the rise. Malnutrition is not uncommon and is a grave complication that negatively impacts various clinical outcomes as it responsible for chronic weight loss. The current study aims to assess the nutritional status of IBD patients. Patients and methods: A cross sectional study was conducted in Medical city hospital for a period of 6 months, the study included 201 IBD patients were chosen randomly upon their entry to Gastrointestinal outpatient clinic (every 5th patient), patients were interviewed, their files were checked, data were collected and their current nutritional intake were logged into excel sheet, Subjective Global Assessment (SGA) nutritional assessment were done for each patient. In all statistical analysis, P value ≤0.05 is considered significant. Results: More than half 105 (52.2%) of the patients had UC and the remaining 96(47.8%) had CD.
Early versus delayed rehabilitation protocol after arthroscopic rotator cuff repair
Authors: Ahmed Waleed Saber , Nahass Bassem Galal Eldein El , Mohamed Waleed Reda , Ibrahim Mona Mohamed
Published: September 2022

Objective: To assess the effect of immobilization versus early range of motion exercises in treating primary arthroscopic rotator cuff repair secondary to full-thickness tear. Design: Parallel group randomized clinical trial. Participants: 30 patients with primary arthroscopic rotator cuff repair secondary to full-thickness tear participated in the study. Interventions: Patients were divided into two groups, 15 in each group. The first group (A) received early range of motion (ROM) exercises started 2 weeks post-operative; and the second group (B) immobilized immediately post operative and received delayed range of motion exercises started 6 weeks post-operative. Main outcomes: Shoulder pain and function were assessed by shoulder pain and disability index (SPADI). ROM of shoulder flexion, abduction, and internal rotation were assessed by standard goniometer. Scapular protraction was assessed by digital caliper and scapular upward rotation was assessed by bubble inclinometer. All outcomes were assessed in both groups 6 weeks, 3 months and 6 months postoperative. Results: A significant increase in flexion, abduction and internal rotation ROM at 6 weeks, 3 months and 6 months was observed between groups in favor of Group A.
cross sectional study on cytomorphological diagnosis and clinical presentation of various thyroid diseases in Tribal areas of Odisha
Authors: Mishra Shree Kumar Chinmayananda , Rout Rabinarayan , Behera Debasis Debadatta , Sahu Binod Kumar
Published: September 2022

Introduction: Thyroid is an endocrine gland which is affected by various types of pathology including non-neoplastic and neoplastic conditions.  The disease burden is very high in costal areas of India and Himalaya areas. Fine needle aspiration cytology (FNAC) is an important mode of initial diagnosis of various diseases of the gland. The study was conducted in various tribal areas of Odisha to find various clinical features and cytomorphological (FNAC) finding of various pathology of thyroid. Methodology: The study included total 210 cases of thyroid disorder over a period of 1 year from October 2019 to September 2020 in the department of pathology. Cytomorphological diagnosis by FNAC and brief clinical data were taken into consideration for statistical analysis. Result: This study revealed that female cases were 86.2 % and male 13.8 % and highest percentage (44.28 %) of patients were in age group 21 to 40 years. Other than gland enlargement three most common presentations were heat intolerance, cold intolerance and tachycardia.
أثر حالة طوارئ كوفيد-19 على الحقوق والحريات بدول شمال إفريقيا: حرية التعبير في المغرب وتونس
Authors: النويني الحافظ
Published: September 2022

تسعى هذه الورقة البحثية إلى تسليط الضوء على تأثير حالة الطوارئ على ممارسة الحقوق والحريات –خاصةً حرية التعبير والرأي– بدولتي المغرب وتونس، اللتين أفرزتا تطورًا دستوريًا وحقوقيًا خلال السنوات الأخيرة –المغرب (دستور 2011) وتونس (دستور 2014). تكمن أهمية الورقة في إبراز الأثر الذي خلفه إعلان دولتي المغرب وتونس لحالة الطوارئ –لمواجهة كوفيد-19– على الحقوق والحريات الأساسية، والقيام بتقييم لهذا التقدم الدستوري والحقوقي من خلال ما واجهته كلتا الدولتين خلال أزمة كوفيد-19. الدراسة تجيب عن إشكالية رئيسية تتمثل في مدى تأثير الإعلان عن حالة الطوارئ لمواجهة كوفيد-19 بالمغرب وتونس على الحقوق والحريات وخاصة حرية الرأي والتعبير. وخلصت النتائج إلى أن دولتي المغرب وتونس لا زالتا تجابهان ضعفًا في الضمانات الدستورية لحرية التعبير وبعدها الحقوق والحريات الأساسية، وكذا تعيشان على واقع ممارسة سلطوية للأجهزة التنفيذية والأمنية التي لا تتوانى في استغلال أي ظرف استثنائي لكسب مزيد من السلطة والصلاحيات.
النضالات الاجتماعية-السياسية في السودان والجزائر مُعرضة للخطر في خضم أزمة كوفيد-19
Authors: ناكورا سفيان فيليب , كريتا سارة
Published: September 2022

تفشت جائحة كوفيد–19 في السودان والجزائر أثناء واحدة من أخطر مراحل الانتقال السياسي في البلدين. تفحص هذه الدراسة كيف استغلت السلطات في البلدين الجائحة لتحقيق مكاسب سياسية؟ كيف ستُكيّف الحركات الاحتجاجية في البلدين من نضالاتها، في ظل التدهور الاجتماعي/الاقتصادي وانعدام الاستقرار السياسي اللذان يصبان في صالح السلطة؟ كانت الجائحة عاملًا محفزًا لآليات الثورة المضادة في البلدين، وإن اختلفت كثيرًا الأدوات والاستراتيجيات التي تسلحت بها النظم القديمة هنا وهناك. تستند هذه الدراسة إلى إطار نظري مقارن، قوامه مقابلات نصف مهيكلة والمنهج البحثي الكيفي. بينما كثفت السلطات الجزائرية من قمعها للحركة الاحتجاجية في سياق الجائحة، ففرضت قيودًا مشددة على الحريات والحقوق الرقمية؛ فإن النخب القديمة في السودان استغلت الأزمة لتأطير نفسها بصفتها المؤسسة الوحيدة القادرة على حماية المصالح العامة ومكافحة كوفيد–19.
Socio-psychological background of national games
Authors: S.М. Меdеubеk
Published: September 2022

The article is about the socio-psychological aspect of folk games, which stood at the origins of the formation of the centuries-old culture of the Kazakh people, although, they are still poorly studied. The main object of the study is the intellectual game «Uyshik-uyshik», that is an integral part of the national culture and contributes to the formation of personality in the first years of the person’s life. Anattempt has been made to study the nature of national games. Collected materials, works of shcolars showed a gap in the study of this topic. The article examines the abilities of the participant of the game: imagination, creativity, imitation, rivalry, worldview, orientation in time and space, also explains the conditions and rules of the game. It is noted that one of the conditions for the formation of children’s speaking skills is listening; the formation of intellectual abilities is due to the ability to verbally express what they see, hear and think. This is facilitated by the children’s game «Uyshik-uyshik». The relations between the players are based on the principles of solidarity, understanding, respect, friendship, and this serves as a socio-psychological basis for instilling universal values in children. The role of the game as the foundation of the formation of a mature person is proved. The result of the research and evidence revealed the socio-psychological significance of the game.
The Effect of Promotion, Customer Relationship Management and Brand Satisfaction on Customer Loylity: Netflix Indonesian
Authors: Tarmidi Didi , Irgandi Dimas Harvid
Published: September 2022

The development of the video-on-demand industry has made many new players want to jump right in, which was originally just a movie vendor to Netflix, now it is a competitor such as Disney+ Hotstar, HBO, and Amazon Video Premiere, VIU, & Vidio. The Information reported that 60 percent of subscribers canceled Netflix subscriptions in Q4 2021 and in Q1 2022 Netflix lost 200,000 subscribers and is projected to lose 2.5 million subscribers by 2022. This study aims to determine how sales promotion, CRM, & Service Innovation affect customer loyalty. The research method used in this study is a quantitative method with multiple regression analysis. The population in this study were people who had been or were using the Netflix service. The sampling technique used in this study was Nonprobability sampling and the size of the sample in this study was calculated by Bernoulli's formula with a total of 100 respondents, with the SPSS25 for Windows test tool. The results showed that promotion, customer relationship management, and brand satisfaction affect Netflix customer loyalty. The magnitude of the influence of promotion, service innovation, and brand satisfaction on customer loyalty is 37%.
Dakwah Modern Pada Era Konvergensi Media: Studi Kasus Youtube Pondok Pesantren Nurul Jadid
Authors: Aisyah Nur , Rofiah Sawiyatin
Published: September 2022

Penelitian ini bertujuan untuk mengetahui bagaimana Pondok Pesantren Nurul Jadid memanfaatkan era konvergensi ini sebagai media untuk berdakwah secara modern. Pondok Pesantren Nurul Jadid adalah salah satu Pondok Pesantren terkenal di Jawa Timur. Pesantren ini dikenal sebagai pesantren modern, karena dalam lingkungannya menerapkan budaya modern tanpa menghilangkan sisi tradisional di dalamnya. Di zaman yang semakin maju ini, penerapan dakwah modern sangat dianjurkan untuk menyampaikan ajaran islam kepada masyarakat milenial dengan menggunakan media-media modern sebagai wasilah antara da’i dan mad’u. Melihat zaman yang terus berkembang memungkinkan untuk penyampaian dakwah secara kreatif serta inovatif agar dapat menarik perhatian masyarakat maya kepada dakwah yang disampaikan. Didalam penelitian ini menggunakan pendekatan kualitatif jenis fenomenologi dengan teknik pengumpulan data, menganalisis data, wawancara serta observasi secara langsung. Hasil dari penelitian ini Pondok Pesantren Nurul Jadid sebagai Pesantren modern menerapkan media konvergensi sebagai media untuk mengajak orang lain dalam kebaikan, mengingatkan seseorang akan hari akhir, menyeru kepada yang ma’ruf dan mencegah kepada yang mungkar dengan dakwah yang dikemas secara rapi dan modern.
Islam Dan Masyarakat Pluralistik Indonesia Dalam Perspektif Dakwah
Authors: Mustofa Muhamad Bisri , Fauzi Machfudz , Hidayat Rahmat , Wuryan Siti
Published: September 2022

Da'wah and society are complementary sides of the coin in the process of Islamic da'wah. Da'i and the community who are both elements of da'wah become vital objects in the process of success of da'wah. Da'wah that is oriented to an individual piety and generally social must pay attention to things that are very urgent, namely the local wisdom of the local community. For example in the hegemony of the struggle and the long journey of da'wah in Indonesia, which lives with the heterogeneity of society and the majority is Muslim and has religious characteristics. Differences in race, ethnicity, culture, ethnicity, language, and accent from various regions are used as the foundation and fundamental value of religious religiosity as a belief. As a form of purification and for the effectiveness of the implementation of da'wah, every da'wah interpreter or dai must rely on the texts of the Qur'an and Hadith. Expertise in an effort to respond to the conditions of the community that he will preach is a form and management of da'wah that must be organized from a da'wah interpreter. In addition, the Indonesian people have a plural society structure. Then if every dai or da'wah interpreter pays attention to the conditions of this very pluralistic society, it will certainly affect all kinds of da'wah strategies that will be launched to the community. The needs and desires of the diverse plural society in discussing religion must be considered and able to be captured by the da'wah interpreter in concocting his da'wah so that it reaches a pluralistic society like Indonesia. And such da'wah should be a special concern of da'wah activists and each da'i is expected to be able to carry out his da'wah to be able to maximize the aspect of religious development for the people. So there are various Islamic studies that can be used as a stepping stone in determining the direction of da'wah, especially in Islamic society and in general pluralistic society in Indonesia. The conception of da'wah that includes the social, cultural, emotional arguments of the community is expected to be able to answer all the challenges of da'wah in the pluralistic body of society. It is used as a form to build an ideal society khoirul ummah as a form of manifestation of the development of the ummah firmly. The nature of Islam that the lil a'lamin is felt to be enough can be an injection that the empowerment of the Muslim community both mentally and spiritually in the effort to realize the welfare and unity of the ummah is very appropriate. Other forms are religious social and national social. These are the pluralistic values ​​embraced by the majority of Indonesian society.
Islamic Boarding Schools: Among Da'wah, Education, and Moderation Way in Islam
Authors: Vishkurti Roland
Published: September 2022

This article describes the education system and da'wah methods in Islamic boarding schools in the current era of information and communication technology advancement. In particular, in aspects related to nation building, both on a local and national scale in Indonesia. In fact, at the international level, where Indonesia can become a model mecca for Islamic education and da'wah for Islamic countries. in theory and concepts that are used as the basis for elaborating the topic in question are Wasathiyah Islam, national insight, entrepreneurship or entrepreneurship, and optimizing technology for the potential development of Islamic boarding schools. The method used for the preparation of this article is ethnography. A number of data collection and analysis techniques were carried out to formulate conclusions, including field observations, interviews, and literature review, both printed and presented in electronic media. Field observations and interviews were conducted on a digital basis. Either by observing through documentation on social media of Islamic boarding schools, or through interviews via email with a number of Islamic boarding school practitioners in Indonesia. The analysis was carried out through data reduction, presentation of discussions, and formulation of final results. Based on the research that has been done, it can be concluded that Indonesian Islamic boarding schools have the opportunity to become the axis of world Islamic moderation education. Moreover, so far, Islamic boarding schools in Indonesia have always campaigned for a central Islam, which is neither extreme nor liberal. Pesantren always instills national insight in the students and preaches it to the public. Islamic boarding schools teach independence in the economic field to students through a curriculum that has linearity with entrepreneurship. The use of Islamic boarding school social media as a support for the duties and functions of this educational institution is pursued in line with the progress of the times.
Islamic Boarding School Marketing Communication and Da'wah Through Tik-Tok
Authors: Isnaini Muhammad , Fauzi Ahmad
Published: September 2022

Marketing communication is a means of informing, persuading, and reminding consumers directly or indirectly about the products and brands being sold. In the context of this research, marketing communication is carried out with regard to the service products offered by the Asy-Syarifiy Islamic boarding school. In particular, that is done through the Tik-Tok social media account. Because it is classified as an Islamic educational institution, in each stage of marketing communication, there are nuances of preaching that are delivered. Da'wah and marketing communications are the focus of research in this article. The Tik-Tok account analyzed is @Kingzadma which belongs to the boarding school caregiver. The purpose of this study is to describe the da'wah model and marketing communication strategy of the Asy-Syarifiy Islamic boarding school through social media Tik-Tok @Kingzadma. This study uses a qualitative method. Data collection techniques using interviews, observation and documentation. Based on the results of the research, it is known that the da'wah model and marketing communication strategy carried out by the Tik-Tok @Kingzadma account uses four elements, namely, entertainment, interaction, trendiness and customization. Da'wah and marketing communications are carried out through the exploration of these four elements. Entertainment is everything in the form of words, places, objects, behaviors that can be comfort or consolation for a difficult or sad heart. Interaction is a meeting between a person and another individual. Trendiness is the ability to browse trending content on Tik-Tok and adapt it to your own content. Customization is a presentation in a video or video display to make it more interesting.
Rudimentary Horn Pregnancy- A diagnostic dilemma
Authors: Khanam Deeba , Shahrukh Naghma
Published: September 2022

Abstract
Pregnancy implanted in the rudimentary horn of unicornuate uterus is very rare with an incidence of 1 in 75,000 to 1 in 150,000 pregnancies. Half of them rupture, and 80% of the rupture occurs in first and second trimesters. Atrocious outcomes are reported. Horn pregnancy rarely reaches third trimester and when it does the diagnosis becomes more challenging. Ectopic in unicornuate rudimentary horn of uterus is difficult to diagnose even with best facilities available. Consequences are grave with slightest error of radiological and clinical judgment.
Here we present case series of women who had rudimentary horn pregnancy and presented with varied clinical presentation, however they went undiagnosed even after radiological assessment and it lead to exaggerated maternal morbidity. The purpose is to spread awareness of all such rare cases where maternal and fetal wellbeing is jeopardized, and accentuates the significance of high index of suspicion in all such cases
Role of Endoscopy in Patients Presenting With Dyspepsia in Western Up
Authors: Maurya Arvind , Gupta Akhil , Agarawal Diksha
Published: September 2022

Background: Dyspepsia is one amongst the most common clinical disorder. Dyspepsia could be a common clinical problem. The common organic causes of dyspepsia include peptic ulceration, esophagitis and cancer. However, controversy remains over the role of endoscopy in patients with dyspepsia.
Objective: Objective of the study was to evaluate the role of endoscopy in patients presenting with dyspepsia, assess chief complaints and endoscopic findings in each patient and making diagnosis for better and early treatment.
Material and Method:
This retrospective was conducted in the Department of Surgery, Muzaffarnagar Medical College and Associated Hospital from January 2021 to January 2022. The clinical data were collected after detailed history and informed consent.
Results
A total of 100 cases were enrolled for this study. Fifty percent were male. The mean age was 38.83±15.33 years. Forty eight patients were vegetarian, forty patients were non-vegetarian and twelve patients were both vegetarian and non-vegetarian. Nineteen patients (19%) had a history of smoking, 18% had the co-morbid condition and 05 (5%) were consuming alcohol. The endoscopy findings included gastritis in 38 cases, Gastro-esophageal reflux disease in 39 cases, 12 subject having Hiatus Hernia, duodenitis in 6 patients, 30 cases were RUT positive and malignancy in 2 patients.
Conclusion:
Patients with dyspepsia should undergo endoscopy. Endoscopy revealed normal findings or miscellaneous irrelevant findings in the majority of patients.
ECCENTRIC EXERCISE IN THE TREATMENT OF TIBIALIS POSTERIOR TENDINOPATHY: A CASE REPORT
Authors: Samardzic Vesna , Zlaticanin Ratko
Published: September 2022

Introduction Tibialis posterior tendinopathy is a disabling, frustrating, and progressive musculo-skeletal condition that is commonly seen in middle-aged women. The etiology of this overuse injury is likely to be multifactorial, so it is necessary to take into account intrinsic and extrinsic risk factors for effective treatment. Evidence of treatment protocol is insufficient and of limited quality. Conservative treatment is generally undertaken in the early stages of the condition. In conservative treatment, physical therapy and a program of eccentric strengthening exercises are especially emphasized.
Case report We present a case of a 48-years-old woman diagnosed with tibialis posterior tendinopathy. The patient could not participate in recreational sports activities and had a significant limitation in walking. Over a five-weeks period the patient had ten sessions of physical therapy. The applied individually tailored physical therapy program was based on eccentric strengthening exercises.
Conclusion The implemented physical therapy program has led to a significant reduction in pain and a return to sports activities. This case report shows that physical therapy program based on eccentric exercise regime can relieve symptoms and restore functional ability for short period in patient with tibialis posterior tendinopathy.
Đánh giá khả năng chịu động đất của khung bê tông cốt thép theo phương pháp phổ khả năng
Authors: Sáng Nguyễn Vĩnh , Dũng Nguyễn Anh , Thắng Nguyễn Ngọc
Published: September 2022

Thiết kế kết cấu kháng chấn dựa theo tính năng (PBSD) là phương pháp thiết kế xét sự làm việc ngoài miền đàn hồi khi chịu tác động của động đất, phương pháp này đang được phát triển và ứng dụng ở các nước phát triển trên thế giới. Trong khi đó, thiết kế kháng chấn theo Tiêu chuẩn Việt Nam TCVN 9386 - 2012 đánh giá ứng xử đàn dẻo thông qua hệ số ứng xử q còn nhiều hạn chế như chưa đánh giá được quá trình “phi tuyến – chảy dẻo” của kết cấu dẫn tới sự phân phối nội lực trong các cấu kiện. Trong nghiên cứu này, một phương pháp đánh giá “mức tính năng” của kết cấu được thiết kế theo các Tiêu chuẩn Việt Nam hiện hành được trình bày bằng phương pháp PBSD thông qua cơ sở lý thuyết và mô hình kết cấu. Đây sẽ có công cụ hữu ích cho các kỹ sư khi thiết kế công trình chịu động đất theo PBSD.
Mở rộng mô hình giàn ảo cho đài cọc bê tông cốt thép chịu tải trọng lệch tâm và có cọc chịu kéo
Authors: Tuấn Nguyễn Hữu Anh , Hằng Nguyễn Thị Tuyết
Published: September 2022

Mô hình chống-giằng được dùng để phân tích những vùng bất liên tục trong kết cấu bê tông cốt thép khi giả thiết tiết diện phẳng không còn phù hợp. Các tiêu chuẩn quốc tế khuyến nghị dùng phương pháp giàn ảo khi thiết kế đài cọc có tỷ lệ nhịp trên chiều cao nhỏ hơn hai. Các chỉ dẫn thiết kế thường xét đài cọc chịu lực nén đúng tâm từ cột, với mô hình chống-giằng đơn giản, các cọc đều chịu nén và có phản lực đầu cọc bằng nhau. Bài viết này mở rộng mô hình giàn ảo theo tiêu chuẩn châu Âu để tính đài cọc chịu tải trọng lệch tâm, xét cả trường hợp mô men chân cột đủ lớn dẫn đến một số cọc trong đài chịu kéo. Để đảm bảo điều kiện cân bằng, nhiều thanh chống và thanh giằng được đưa thêm vào mô hình giàn ở các vị trí thích hợp. Kết quả tính toán trên giàn ảo phẳng và không gian cho thấy, ngoài thanh giằng ở đáy đài thì nội lực kéo còn có thể xuất hiện trong thanh giằng ở mặt trên, thanh giằng đứng và thanh giằng xiên. Do đó diện tích và chiều dài neo cốt thép cho các thanh giằng này cần phải được quan tâm. Các lực kéo trong thanh giằng đứng và xiên sẽ không được phát hiện nếu đài cọc được tính bằng phương pháp quen thuộc như một dầm lật ngược chịu uốn.
Phân tích việc bố trí, lựa chọn van khí trên đường ống cấp nước
Authors: Dũng Nguyễn Tiến
Published: September 2022

Van khí là thiết bị cơ học thủy khí được thiết kế để tự động xả khí trong khoảng thời gian điền nước, xả nước, của hoạt động một tuyến ống cấp nước hoặc của một hệ thống cấp nước. Sự vận hành an toàn và hiệu quả của một tuyến ống phụ thuộc vào việc loại bỏ liên tục không khí ra khỏi đường ống. Bài báo này đề cập đến việc lựa chọn các loại van khí và vị trí đặt van khí trên tuyến ống cấp nước.
Một số đề xuất nhằm nâng cao hiệu quả dự án nhà ở xã hội tại Tiền Giang
Authors: Lê Minh Quang , Long Lê Hoài
Published: September 2022

Phát triển nhà ở xã hội, là một trong những nhiệm vụ trọng tâm được Đảng và Nhà nước đặc biệt quan tâm nhằm tạo điều kiện cho các nhóm đối tượng gặp khó khăn về nhà ở có được chỗ ở ổn định, an tâm lao động và sản xuất nhằm tạo thêm của cải, vật chất cho xã hội, góp phần vào sự phát triển bền vững, tiến bộ của xã hội. Tuy nhiên, thực tế phát triển nhà ở tại một số địa phương, trong đó có tỉnh Tiền Giang vẫn còn nhiều hạn chế, khó khăn. Một trong những nguyên nhân là do chưa giải quyết được hài hòa mối quan hệ giữa nhu cầu của người dân và lợi nhuận đạt được của dự án. Chủ đầu tư chưa tìm hiểu kỹ thị trường và nhu cầu thực tế của người dân Tiền Giang về nhà ở xã hội. Mặt khác, qui mô, kiến trúc của các dự án cũng chưa phù hợp với tập tục, xu hướng của địa phương dẫn đến giá bán, cho thuê nhà ở quá cao, không phù hợp thực tế trong khi nhu cầu thực tế của người dân vẫn chưa được giải quyết. Do đó, cần phải tiếp tục nghiên cứu tìm ra giải pháp, phương hướng đúng đắn cho các dự án phát triển nhà ở xã hội tại Tiền Giang nhằm nâng cao hiệu quả các dự án đồng thời giải quyết được nhu cầu thiết thực của người dân. Trong bài viết này, từ việc thu thập, tổng hợp, đánh giá nhu cầu thực tế về nhà ở xã hội tại Tiền Giang, các tác giả với mục tiêu tìm một số đề xuất nhằm nâng cao hiệu quả các dự án phát triển nhà ở xã hội tại Tiền Giang.