bluuebunny/crossref_metadata_2025 huggingface dataset:
A behavioral economics analysis of the participation in early childhood development social programs promoted by civil societies in Mexico
Authors: Serván-Mori Edson , Pineda-Antúnez Carlos , Bravo-Ruiz María L. , Molina Mariana , Ramírez-Baca Martín I. , García-Martínez Angélica , Quezada-Sánchez Amado D. , Orozco-Núñez Emanuel
Published: March 2022

Based on a behavioral economics (BE) approach, we analyzed the decision to participate in an early childhood development (ECD) program implemented in Mexico by a non-governmental organization. We conducted a literature review and a qualitative study of four localities participating in the ECD program. Situated in the state of Oaxaca, these communities are characterized by high and very high levels of social marginalization. From May 20 to 30, 2019, we collected primary data through semi-structured interviews (n = 30) and focus groups (n = 7) with a total of 61 informants (51 women and 10 men). We then performed an inductive systematic analysis of the data to identify documented cognitive bias associated with the decisions of individuals to participate and remain in or abandon social programs. The interviewees were living in conditions of poverty, facing difficulties in meeting even their most basic needs including food. Program participants attached far greater weight to incentives such as the basic food basket than to the other benefits offered by the program. The four localities visited maintained traditional views of domestic roles and practices, particularly regarding child-rearing, where women were in charge of childcare, home care and food preparation. Problems linked to child malnutrition were a decisive factor in the decision of residents to participate and remain in the program. Testimonials gathered during the study demonstrated that the longer the mothers remained in the program, the more they understood and adopted the concepts promoted by the interventions. In contexts marked by economic vulnerability, it is essential that ECD programs create the necessary conditions for maximizing the benefits they offer. Our analysis suggests that cognitive load and present bias were the biases that most severely affected the decision-making capacity of beneficiaries. Therefore, considering loss aversion and improving the management of incentives can help policymakers design actions that “nudge” people into making the kinds of decisions that contribute to their well-being.
Patterns of home care assessment and service provision before and during the COVID-19 pandemic in Ontario, Canada
Authors: Sinn Chi-Ling Joanna , Sultan Heebah , Turcotte Luke Andrew , McArthur Caitlin , Hirdes John P.
Published: March 2022

Objective

The objective was to compare home care episode, standardised assessment, and service patterns in Ontario’s publicly funded home care system during the first wave of the COVID-19 pandemic (i.e., March to September 2020) using the previous year as reference.

Study design and setting

We plotted monthly time series data from March 2019 to September 2020 for home care recipients in Ontario, Canada. Home care episodes were linked to interRAI Home Care assessments, interRAI Contact Assessments, and home care services. Health status measures from the patient’s most recent interRAI assessment were used to stratify the receipt of personal support, nursing, and occupational or physical therapy services. Significant level and slope changes were detected using Poisson, beta, and linear regression models.

Results

The March to September 2020 period was associated with significantly fewer home care admissions, discharges, and standardised assessments. Among those assessed with the interRAI Home Care assessment, significantly fewer patients received any personal support services. Among those assessed with either interRAI assessment and identified to have rehabilitation needs, significantly fewer patients received any therapy services. Among patients receiving services, patients received significantly fewer hours of personal support and fewer therapy visits per month. By September 2020, the rate of admissions and services had mostly returned to pre-pandemic levels, but completion of standardised assessments lagged behind.

Conclusion

The first wave of the COVID-19 pandemic was associated with substantial changes in Ontario’s publicly funded home care system. Although it may have been necessary to prioritise service delivery during a crisis situation, standardised assessments are needed to support individualised patient care and system-level monitoring. Given the potential disruptions to home care services, future studies should examine the impact of the pandemic on the health and well-being of home care recipients and their caregiving networks.
Psychometric Properties of Indonesian Version Co-Worker Support Scale
Authors: Prihatsanti Unika
Published: March 2022

This study aimed to validate the Indonesian Version of the Co-worker Support Scale. A scale used to measure co-support in organization. The International Test Commission (ITC) Guidelines for Translating and Adapting Test Second Edition procedure used to adapt this scale. A total of 318 employees (M = 44%, F = 56%; SD Age = 8.3) from various organizations were involved in this study. Based on the Rasch model analysis, it indicated that the Co-worker Support Scale has good internal consistency. The result showed that the scale’s factor structure was unidimensional, RV= 60.8%. It means that the items can be effectively able to measure co-worker support. The significant chi-square value indicates that the data is fit to the model, χ2 (4118) = 8017.19, p < .01. The answer choice category option with 5 answer choices can be preserved. Moreover, no differential item functioning was found based on gender, education level, and type of organization. Overall, the results indicated that this 14-item scale, including its psychometric properties, was satisfactorily reliable and valid to measure co-worker support in the organizational context in Indonesia.
The use of the C-eye system in communication and education of children
Authors: Zawichrowska Marta
Published: March 2022

During working with children with communication disorders, they are more and more often accompanied by devices supporting the development of speech. One of them is the C-eye system, which is used especially in two areas – communication and education. This article is an introductory report on the research on the use of high technologies in working with children with developmental disorders, accompanied by deficits in the field of verbal speech. The described case study concerns a child with delayed speech development, without any additional health burden, in whom the etiology of communication disorders has not been determined despite careful diagnostics and many specialist consultations. The article was written on the basis of observations, an interview with the family and the recommendations provided, and presents the original path of therapeutic treatment with the use of the C-eye device, which can be used in work with preschool and early school children. Very important was the neurologopedic diagnosis and research conducted during the therapy, which allowed for the proper definition of therapeutic goals and showed its effectiveness, both in the communication, educational and social sphere.
Entre la distopía y la heterotopía: espacios de la crisis en las novelas de Isaac Rosa
Authors: Smuga Łukasz
Published: March 2022

This paper analyses urban spaces of crisis in Isaac Rosa’s novels La mano invisible (2011), La habitación oscura (2013), and the graphic novel Aquí vivió. Historia de un desahucio (2016) by Cristina Bueno and Isaac Rosa. It explores the dystopian and realistic elements in Rosa’s fiction and proposes to read his works through the lens of Michel Foucault’s essay on other spaces. The article argues that the unusual, quasi-dystopian spaces are of a double nature, typical for heterotopias, and play a significant role in the manner in which Rosa depicts the consequences of the economic crisis in Spain at the beginning of the 21st century.aper analyses urban spaces of crisis in Isaac Rosa’s novels La mano invisible (2011), La habitación oscura (2013), and the graphic novel Aquí vivió. Historia de un desahucio (2016) by Cristina Bueno and Isaac Rosa. It explores the dystopian and realistic elements in Rosa’s fiction and proposes to read his works through the lens of Michel Foucault’s essay on other spaces. The article argues that the unusual, quasi-dystopian spaces are of a double nature, typical for heterotopias, and play a significant role in the manner in which Rosa depicts the consequences of the economic crisis in Spain at the beginning of the 21st century.
A sensitive improved method for analyzing diffusion coefficients of Cs in compacted bentonite with different lengths
Authors: Liu Zhenxing , Sun Yuzhen , Kong Jie , Lee Chuan-Pin , Hua Rong , Liu Weigang , Wang Zhifen , Jiang Qifeng , Li Boping
Published: March 2022

Based on the one-dimensional diffusion theory, the diffusion parameters were obtained from numerical fitting by the Cyclic Initial Value (CIV) program written by MATLAB. Taking the through-diffusion experimental of cesium (stable isotope 133Cs) as an example, on the premise of ensuring accuracy, fitting calculation was used to obtain the diffusion equilibrium time of Cs in different lengths bentonite column. The fitting results of diffusion test for tritium water (HTO) and Cs are both very well. The calculation results of the equilibrium time for Cs diffusion show that the equilibrium time obtained by CIV is less than the experimental period in both groundwater (GW) and seawater (SW). In GW environment, when the sensitivity is at the maximum setting value, the diffusion coefficient of Cs in 1.5 cm bentonite column could be calculated in a shorter period of time. Compared with the experimental period, the time was shortened by 110 days. The main purpose is to verify the feasibility of CIV through the experimental data of Cs in different column lengths. The CIV program can also be used to fit and calculate the experimental data of other ongoing diffusion experiments and get the equilibrium time required for diffusion experiments. It shows that the proposed models offer the advantages of saving experimental time and reducing experimental waste.
Rechnerunterstützte Auslegung von Spindellagerungen
Authors: Perovic Bozina
Published: March 2022

Die Berechnung hydrostatischer und hydrodynamischer, durch exzentrische Kräfte belasteter Spindellagerungen erfordert komplizierte und zeitaufwendige Rechnungen. Sie sind zur optimalen Auslegung der Spindellagerungen sowie ihrer lversorgung unerläßlich und lassen sich numerisch nur mit dem Einsatz von Rechnerprogrammen erstellen.
Total Productive Manufacturing für die chemische Industrie
Authors: Leyhausen Barbara , Mühlbradt Thomas
Published: March 2022

Um im globalen Wettbewerb bestehen zu können, müssen Unternehmen ihre Produktionskonzepte ständig erneuern und optimieren. Auch die chemische Industrie wandelt ihre Produktionsphilosophien und sucht innovative Ansätze, um die Produktionskosten zu reduzieren und die Produktivität zu erhöhen. Der vorliegende Beitrag zeigt anhand von Praxisbeispielen die Transformation der Rationalisierungsansätze des Total Productive Manufacturing (TPM).
Entwicklung des Fachgebietes Qualitätswissenschaft
Authors: Herrmann Joachim , Kostka Claudia
Published: March 2022

Die Wurzeln der Qualitätswissenschaft reichen zurück bis in die Antike. In diesem Beitrag werden ausgehend von der geschichtlichen Entstehung Einblicke in den momentanen Stand der Forschung und die sich abzeichnenden künftigen Entwicklungen dieser Wissenschaft gegeben.
Produktivität, Qualität und Business Excellence
Authors: Masing Walter
Published: March 2022

Die Herstellung qualitativ hochwertiger Produkte ist ebenso wie eine ständig steigende Produktivität gerade in der heutigen Zeit ein „Muß" für die Fertigung. Bei diesen Anforderungen handelt es sich jedoch nicht wie noch immer angenommen um konkurrierende, sondern um kongruente Ziele, da eine hohe Produktivität auch eine hohe Prozeßqualität voraussetzt.
La Iglesia que peregrina en la Calle. Sistematización de prácticas educativas con habitante de calle
Authors: Nieto Johan , Pinto-López Carlos
Published: March 2022

Este artículo tiene como objetivo presentar la sistematización de experiencias que realizaron los autores para reconocer los saberes pedagógicos emergentes de quienes han participado en la peregrinación en las calles (Santamaría-Rodríguez, et al., 2020; Nieto y Santamaría, 2020). Dos ejes centrales surgieron de la experiencia, en primer lugar, un proceso educativo que ha garantizado el acompañamiento a esta población desde la perspectiva del desarrollo humano; y, en segundo lugar, el reconocimiento de la fraternidad cristiana cuya responsabilidad es el acto de confrontar, como principio rector de la ética del cuidado con aquellos que han denominado "hermanos de la calle".
The Mediating Role of Smoking and Body Mass Index on the Relationship between Alcohol Consumption and Blood Triglyceride Levels among Korean Adults: The 7th Korean National Health and Nutrition Examination Survey
Authors: Yoo Yeon Joo
Published: March 2022

Background: Although there are many studies of association between alcohol consumption and hypertriglyceridemia with categorized variables, it is insufficient to study association between quantity of alcohol consumption and triglyceride levels as continuous variables. Therefore, this study investigates direct effect of alcohol consumption on triglyceride levels. Additionally, this study examines indirect effects through smoking and body mass index (BMI).Methods: This study uses data from the 7th Korean National Health and Nutrition Examination Survey. Among the participants, 5,867 adults ≥20 years of age are enrolled. To test the association between quantity of alcohol consumption and triglyceride levels and indirect effects through smoking and BMI, this study conducts multi-regression analysis by SPSS PROCESS macro.Results: The results are as follows. First, alcohol consumption has positive(+) effects on smoking, BMI, and triglyceride levels significantly. Second, smoking and BMI have a positive(+) effect on triglyceride levels significantly. Third, alcohol consumption has positive(+) effects on triglyceride levels through smoking and BMI indirectly.Conclusions: Alcohol consumption has a direct effect on triglyceride levels, also has indirect effects through smoking and BMI positively.
On the finite convergence of the NN classification learning on mistakes
Authors: Norkin V.I.
Published: March 2022

The paper establishes an analog of well-known Novikoff’s theorem on the perceptron learning algorithm’s finite convergence in linearly separated classes. We obtain a similar result concerning the nearest neighbor classification algorithm in the case of compact classes in a general metric space for the case of non-intersecting classes. The learning process consists of gradual modification of the algorithm in misclassification cases. The process is studied in the deterministic setting. Classes are understood as compacts in complete metric space, and class separation is defined as the non-intersection of compacts. The number of learning steps is bounded by the number of elements in some ε-net for the considered classes.
Розв’язання задачі про докритичний стан крайової тріщини в рамках підходу моделі когезійної зони
Authors: Селіванов М.Ф. , Процан В.В.
Published: March 2022

Розглянуто задачу про докритичний стан крайової тріщини нормального відриву в напівнескінченній ізотропній площині. Розв’язок побудовано в рамках підходу моделі зони зчеплення, в основі якої лежить нерівномірний зв’язок між поверхневими силами зчеплення і відриву берегів фіктивного розрізу. Цей розріз моделює зону передруйнування, що утворюється біля фронту тріщини. В основу розв’язку покладено регуляризоване сингулярне рівняння з узагальненим ядром Коші, яке розв’язується методом колокації. Плавність змикання берегів тріщини забезпечується введенням ділянки зростання в закон зчеплення–відриву. Числовий приклад побудовано для згладженого трапецоїдального закону. Проілюстровано відсутність осциляції розв’язку, вказано на появу сингулярності внаслідок розривності граничних умов на контурі модельного розрізу уразі дослідження докритичного стану. Вказано на розбіжності розв’язків рівнянь першого і другого родів для невеликих довжин зчеплення.
Простий синтез гетероциклічних ізостерів бензо[ f ]азулену. Конструювання 2-бензазепінового фрагмента за реакцією Пікте—Шпенглера
Authors: Богдан Н.М. , Іванисенко О.В. , Суйков С.Ю. , Яковлева Г.В. , Швед О.М. , Богза С.Л.
Published: March 2022

Досліджені синтез 5-аміно-4-бензилпіразолів та їх реакції з карбонільними сполуками в умовах реакції Пікте—Шпенглера. Розроблено простий препаративний метод синтезу 4-(3, 4-диметоксибензил)-3(5)амінопіразолів — реакційноздатних поліфункціональних сполук. Створений новий метод формування 2-бенза-зепінового фрагмента в умовах реакції Пікте—Шпенглера на прикладі нової гетероциклічної системи 5, 10-дигідро-4H-піразоло[3, 4-c][2]бензазепіну. На підставі результатів ЯМР досліджень встановлено, що просторова будова азепінового циклу в одержаних гетероциклах залежить від розміру та характеру радикала карбонільного реагенту. Знайдені сполуки з активністю проти збудника лейшманії, що перевищує відомі
Порівняння ефектів колоїдного розчину квантових точок на основі телуриду кадмію та іонів кадмію на проліферативну активність кореневих меристем Allium cepa L.
Authors: Лахтуров А.С. , Смірнов О.Є. , Коваленко М.С. , Капуш О.А. , Джаган В.М. , Швартау В.В.
Published: March 2022

За допомогою стандартної системи Allium-тест досліджено вплив розчину квантових точок на основі те луриду кадмію (CdTe КТ) як потужного цитостатичного ефектора. Цитостатичні ефекти експериментального розчину CdTe КТ на організменному рівні виявлялися у зниженні лінійного приросту та біомаси коренів Allium cepa L., тоді як на рівні проліферативної активності меристематичних клітин коренів зафіксовано зупинку мітотичних поділів. Вплив досліджуваного розчину CdTe КТ у концентрації 10 мкМ порівнювали з ефектами, що спричинені впливом 10 мкМ розчину CdI2. Встановлено різновекторність цитогенетичних порушень. Показано, що розчин CdTe КТ у концентрації 10 мкМ, використаний як субстрат, спричиняв значне інгібування росту коренів та проліферативної активності меристематичних клітин, пригнічуючи мітоз без виявлених кластогенних та анеугенних ефектів. У разі використання 10 мкМ розчину CdI2 як субстрату відмічено підвищення частоти кластогенних патологій мітозу на 24 %.
Cat got your artery? Point of care ultrasound in the evaluation of penetrating trauma by a feline: a case report
Authors: Haley Campbell Belisle , Mackenzie David
Published: March 2022

Point of care ultrasound is an important tool for diagnosis of musculoskeletal and vascular pathology in patients presenting to the emergency department. Superficial vascular and soft tissue structures are well-visualized at the bedside using modern ultrasound systems and have image characteristics that can be rapidly identified. This report describes the use of point of care ultrasound to distinguish between rapidly progressive soft tissue infection and vascular injury following penetrating trauma from a cat scratch. Ultrasound allowed the physician to rapidly make accurate decisions about the next necessary steps in the patient’s care. Point of care ultrasound provides immediate diagnostic information to supplement indeterminate physical examination findings. In this case, it allowed the treating physician to make the diagnosis of arterial injury using ultrasound image characteristics. An integrative approach to ultrasonography of superficial musculoskeletal and vascular structures could enhance clinical decision making and improve care of patients with similar complaints.
Analysis of the accuracy of automatic electrocardiogram interpretation in ST-segment elevation myocardial infarction
Authors: Kim Seongsoo , Kim Wonhee , Kang Gu Hyun , Jang Yong Soo , Choi Hyun Young , Kim Jae Guk , Lee Yoonje , Shin Dong Geum
Published: March 2022

Objective This study aimed to analyze the association between the culprit artery and the diagnostic accuracy of automatic electrocardiogram (ECG) interpretation in patients with ST-segment elevation myocardial infarction (STEMI).Methods This single-centered, retrospective cohort study included adult patients with STEMI who visited the emergency department between January 2017 and December 2020. The primary endpoint was the association between the culprit artery occlusion and the misinterpretation of ECG, evaluated by the chi-square test or Fisher exact test.Results The rate of misinterpretation of the automated ECG for patients with STEMI was 26.5% (31/117 patients). There was no significant correlation between the ST segment change in the four involved leads (anteroseptal, lateral, inferior, and aVR) and the misinterpretation of ECG (all P > 0.05). Single culprit artery occlusion significantly affected the misinterpretation of ECG compared with multiple culprit artery occlusion (single vs. multiple, 27/86 [31.3%] vs. 4/31 [12.9%], P = 0.045). There was no association between culprit artery and the misinterpretation of ECG (P = 0.132).Conclusion Single culprit artery occlusion might increase misinterpretation of ECG compared with multiple culprit artery occlusions in the automatic interpretation of STEMI.
Desconto hiperbólico e efeito magnitude nas decisões intertemporais? Evidências de uma survey com escolhas monetárias
Authors: Gualberto Pereira Antonio , Afonso Luís Eduardo
Published: March 2022

o presente estudo busca responder às seguintes questões: há evidências de inconsistência intertemporal em decisões que envolvem o recebimento de valores monetários? As pessoas estão sujeitas ao efeito magnitude em decisões intertemporais que envolvem o recebimento de valores monetários? O objetivo deste artigo é identificar inconsistências em decisões intertemporais que envolvam o recebimento de recursos monetários em diferentes momentos. Parte-se do pressuposto que decisões intertemporais que envolvem montantes em dinheiro podem ser igualmente afetadas pelo efeito magnitude. Este é um achado robusto na literatura, tendo sido identificado em escolhas hipotéticas que envolvem dinheiro. Para abordar a questão, procedeu-se o cálculo da taxa de desconto implícita dos indivíduos e, em seguida, classificaram-se os indivíduos segundo o construto “impaciência”. Foram utilizados cenários adaptados de Sutter et al. (2013). Na análise dos dados, foi empregado um teste não paramétrico para diferença de médias e identificadas as características mais relevantes dos respondentes da survey. Há evidências de comportamento inconsistente nas decisões intertemporais para os cenários apresentados, com ocorrência de impaciência crescente para intervalos de tempo deslocados para o futuro. Tal achado vai de encontro à literatura empírica sobre desconto hiperbólico. Paralelamente, observou-se a ocorrência do efeito magnitude, ratificando achados anteriores sobre quantias monetárias aplicadas a escolhas intertemporais de longo prazo.
Milkability characteristics of Jersey cows throughout the lactation and their effect on milking induced teat prolongation
Authors:   Czech University of Life Sciences Prague, Faculty of Agrobiology, Food and Natural Resources, Department of Animal Science, 165 00, Gašparík Matúš ,   Prague, Czech Republic
Published: March 2022

The aim of this study was to monitor milkability traits of Jersey cows over the course of lactation, and to investigate how milkability characteristics affected milking induced teat prolongation (MITP; %). For the purpose of the experiment, milkability parameters and teat length of 43 Jersey cows were monitored throughout the lactation. The effects of milk yield, milking time, lag time, average milk flow, and milk flow during various stages of milking on milking induced teat prolongation were evaluated. Jersey cows in this study achieved an average daily milk yield of 16.8 kg with an average milking time of 5 min. The average milk flow was 1.73 kg min-1 and the occurrence of bimodal milk flows was 23.8 %. Milkability characteristics significantly affected MITP. Milk yield, lag time and milk flow at the beginning of milking affected the MITP of both pairs of teats, while average milk flow and milk flow during the second minute of milking showed significant differences only for MITP of front teats. Furthermore, MITP was not dependent on milking time nor milk flow after the second min of milking, but was strongly affected by milk yield and milk flow disturbances at the beginning of milking. Higher MITP was observed for high milk yields, low lag times, normal milk flows at the beginning of milking, and fast milk flows during the milking. Thus, the desired milkability characteristics caused higher MITP. The findings of this study suggest that the high teat prolongation during milking might be interpreted as a positive sign for milking efficiency.
Management pregnance on the background of retrochoric hematoma in the I trimester of pregnancy (Literature review)
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Romanenko T.G. , Zhaloba G.M. ,   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Staselovych L.Y. ,   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine, Voronina K.I. ,   Shupyk National Medical Academy of Postgraduate Education, Kуiv, Ukraine
Published: March 2022

In modern obstetrical and gynecological practice, the problem of miscarriage, one of the manifestations of which is the retrochoric hematoma, does not lose its relevance. Despite numerous studies of the etiology and pathogenesis of this problem, there are still many questions that need answers. The purpose of this systematic review was to highlight the problem of retrochoric hematomas, the etiological features of their occurrence and the importance of treatment in order to avoid the development of further complications, the preservation and prolongation of pregnancy. The features of diagnostics and subsequent therapy with the main pathogenetically grounded drug, micronized progesterone, are considered, which provides early support for pregnancy and a reduction in the frequency of obstetric and perinatal complications that combine into large obstetrical syndromes. Analyzed data from modern world studies suggest that it is progestins (micronized progesterone) that should be the drug of choice in the treatment of miscarriage, which occurs against the background of retrochorial hematoma. The conclusion of the expert group of ESHRE on special issues of early pregnancy is: in women with bleeding in early pregnancy and the formation of retrochoric and retrocopental hematomas the risk of premature birth, the development of fetal growth retardation syndrome, placental abruption in the 2nd and 3rd trimesters is increased. In order to prevent preterm delivery experts recommend prolongation of therapy with micronized progesterone (200 mg per day intravaginally from early pregnancy). In the diagnostics of retrochoric hematoma the tactics of management should be based on the therapy of preserving pregnancy and preventing its further complications. The high efficacy of micronized progesterone Utrozhestan and haemostatic therapy in the treatment of abortion complicated by retrochoric hematoma allows prolonging pregnancy and achieving favorable perinatal outcomes. The absence of side effects and good tolerance extend the possibilities of using Utrozhestan by women with retrochoric hematoma in case of a threat of termination of pregnancy. Key words: retrochorial hematoma, miscarriage, micronized progesterone, large obstetrical syndromes, Utrozhestan.
The role of vitamin D in maintaining women’s health and the modern principles of correction of the D-status
Authors:   Danylo Halytskyy Lviv National Medical University, Ukraine, Pуrohova V.I. , Shurpyak S.O. ,   Danylo Halytskyy Lviv National Medical University, Ukraine, Oshurkevich O.O. ,   Danylo Halytskyy Lviv National Medical University, Ukraine, Zhemela N.I. ,   Danylo Halytskyy Lviv National Medical University, Ukraine, Okhabska I.I. ,   Danylo Halytskyy Lviv National Medical University, Ukraine
Published: March 2022

The article presents an assessment of the effectiveness of various doses of cholecalciferol for the correction of vitamin D-deficient states. The objective: to study the prevalence of vitamin D deficiency in women of reproductive age with reproductive health disorders and the effectiveness of its correction with the use of Olidetrim. Materials and methods. Surveyed 350 residents of Lviv and Lviv region, aged 20 to 35 years, who planned the implementation of reproductive plans. Vitamin D deficiency was diagnosed in 275 (78.6%) of the women surveyed, of whom 160 were included in further research with informed consent. Depending on the proposed scheme for the correction of vitamin D deficiency, the patients were divided into groups with distribution into subgroups depending on the level of 25(OH)D in the blood. Results. It has been established that vitamin D-deficient states in women of reproductive age at the preparatory stage for pregnancy occur in 78.6% of cases, while vitamin D deficiency is most often manifested in women with a BMI of 30–35 kg/m2. The intake of vitamin-mineral complexes containing 400 IU of cholecalciferol, as well as the daily intake of 2000 IU of cholecalciferol, does not prevent the development of deficiency of vitamin D and does not provide for their correction. The use of cholecalciferol in a daily dose of 4000 IU (Olydetrim 4000, Polpharma, Poland) during 3 months of pregravid preparation allows correction of the balance of vitamin D, but it is also insufficient to eliminate severe vitamin D deficiency, which determines the need to take higher doses cholecalciferol in this category of women. Conclusion. The results indicate a significant prevalence of vitamin D deficiency in women of reproductive age. Correction of deficiency and deficiency of vitamin D from the pregravid preparation stage and during the first trimester of gestation reduces the incidence of early and late gestational complications. Key words: vitamin D deficiency, cholecalciferol, Olidetrim, pregnancy complications.
Prophylaxis of placental dysfunction at women with varicose illness of the bottom extremities
Authors:   Ivano-Frankivsk National Medical University, Ukraine, Motsyuk Yu.B.
Published: March 2022

The objective: to develop a technique of prophylaxis of placental dysfunction at women with varicose illness of the bottom extremities. Materials and methods. We surveyed 90 patients among whom 60 – with varicose illness of the bottom extremities which were it is divided into two groups, according to algorithm of the used treatment-and-prophylactic actions. The control group was made by 30 pregnant women without obstetric and somatic pathology, the labours through natural patrimonial ways. In a complex of the conducted researches were clinical, functional, laboratory, morphological and statistical methods of research. Results. Results of the conducted clinical researches testify that use of the algorithm improved by us at women with varicose illness of the bottom extremities allows to reduce significantly the frequency of obstetric and perinatal pathology at women of group of high risk that is confirmed by data of laboratory, functional and tool methods of researches. Conclusion. The results received by us allow to recommend the algorithm improved by us for use in practical health care. Key words: placental dysfunction, varicose illness of the bottom extremities, prophylaxis.
The urethral closure function status in pregnant women suffering from overactive bladder syndrome
Authors:   National Pirogov Memorial Medical University, Vinnytsia, Ukraine, Kostiuk I. , Chayka G. ,   National Pirogov Memorial Medical University, Vinnytsia, Ukraine, Garnets Yu. ,   National Pirogov Memorial Medical University, Vinnytsia, Ukraine
Published: March 2022

The ultrasound method of investigation was proposed as the first step in the diagnosis of urinary incontinence, since the average value of the thickness of the bladder wall and the size of the urethral sphincter in the works of many urologists are correlated with the presence of overactive bladder. The objective: was to determine the sonographic parameters of the urethral closure in pregnant women with overactive urinary bladder. Materials and methods. In this article, an estimation of such ultrasound signs of the urethral closure apparatus, such as funnel-like urethral enlargement, bladder wall thickness measurement, bladder volume, residual urine volume, were performed. The diagnostic value of the cervical-bulk test in pregnant women with overactive urinary bladder is assessed. The obtained results were compared with the same in healthy pregnant women. Results. The index of bladder wall thickness with age increases, as in women with overactive bladder, and in practically healthy women. However, significantly higher value of this indicator (p<0,001) was found in the group of women with overactive bladder. In the third trimester of pregnancy, a positive cervical-bleb test was found in all patients with overactive bladder. In the group of pregnant women with overactive bladder, significantly less volume of the bladder and increased volume of residual urine, which confirms the world data. Conclusion. Data of spontaneous contractions of detrusor in pregnant women suggest that this indicator is a characteristic diagnostic feature of overactive bladder. Key words: pregnancy, ultrasound examination, urethral closure, overactive bladder.
Actual dynamics of the species structure of etiological pathogens of urinary tract infections in children and antibacterial sensitivity of this pathogenes
Authors:   Taras Shevchenko National University of Kyiv «Institute of Biology and Medicine», Ukraine, Budnik T.V. , Kvashnina L.V. ,   SI «Institute of Pediatrics, Obstetrics and Gynecology named after academician О.M. Lukyanova of the NAMS of Ukraine», Kyiv, Chernyavskaya M.L. ,   VSP No.3 «Dobrobut - Polyclinic LLC», Kyiv, Ukraine
Published: March 2022

Understanding the structure of etiopathogenes of urinary tract infections (UTIs) in children, the state of antibacterial resistance (ABR) is an important component of the empirical choice of antibiotics in treatment. Purpose - to study the species structure of UTIs pathogens in children, the prevalence of ABR the rate of its formation at the present stage. Materials and methods. The study involved 2754 hospital and outpatient children aged 0 to 18 years with UTIs in the active phase of the disease for the period 2009-2019. The contingent of subjects was divided into 3 groups: patients for 2009, 2014 and 2019 years of follow-up. Results. Escherichia coli was recognized as the leading uropathogen in all observation groups: in the 1st group (2009) its share was 47% (158/337), in the 2nd (2014) - 64% (210/328), in 3rd (2019) - 66.5% (252/379). The high dynamics of ABR prevalence of Escherichia coli was recognized: an increase of 11% in 2019 compared to 2014; by 18.8% compared to 2009. Thus, in 2019, every second child had resistance (57.6%±1.6 (1586/2754)) and every third - polyresistance (27.4%±3), 04 (755/2754)). We found an increase in the relative risk of ABR in 2019 1.6 times compared to 2014 and 3 times compared to 2009. The mathematical forecast of the prevalence of resistant strains of Escherichia coli for 15 years approached 100% (y=9.5x6+41=98%) at R² = 0.9918. For 10 years the indicator corresponded to 88.5%, for 5 years - 79%. The prognostic increase in ABR relative risk of 2.9-3.7 times in the next 5-10 years has been established. Conclusions. The obtained data are of great practical importance for general practitioners and specialists, as they indicate a high rate of formation of resistant strains of Escherichia coli and other pathogens among children with UTIs, which complicates the empirical choice of antibacterial therapy. The study was conducted in accordance with the principles of the Declaration of Helsinki. The research protocol was approved by the Local Ethics Committee of all the institutions mentioned in the work. Informed consent of the children's parents was obtained for the research. The authors declare no conflict of interest. Key words: urinary tract infection, children, etiological pathogens, antibacterial resistance.
Characteristics of lipid metabolism in adolescents with obesity and signs of metabolic syndrome
Authors:   V.N. Karazin Kharkiv National University, Ukraine, Buznytska O.V.
Published: March 2022

One of the most important issues of modern medical science is the metabolic syndrome, the origins of which begin in childhood and adolescence. Diagnostic criterias for metabolic syndrome for children are developed by the International Diabetes Federation (IDF, 2007). It is known that atherogenic dyslipidemia is one of the main and early criteria of the metabolic syndrome and plays an important role in the pathogenesis of the atherosclerotic process and associated cardiovascular diseases. Due to the insufficient amount of information about the nature of dyslipidemia in adolescents and the possibilities for its correction and prevention, the study of this problem is relevant. Purpose - to study the characteristics of lipid profile in adolescents with obesity and signs of metabolic syndrome. Materials and methods. We examined 200 obese patients aged 14-18 years, who were divided into two groups: with and without metabolic syndrome according to current recommendations. The control group consisted of 30 adolescents with normal body weight of a similar age. To achieve the goal, all adolescents underwent a comprehensive examination with a focus on the lipid profile of blood using standardized methods in accordance with the IFCC recommendations on a Cormay Multi semi-automatic photometer. The level of β-lipoproteins in blood serum was determined by the turbidimetric method of Burstein M. and Samaille F. Results. In adolescents with metabolic syndrome, signs of atherogenic dyslipidemia were found, manifested in the form of elevated levels of triglycerides, low and very low density lipoprotein cholesterol, β-lipoproteins, a tendency to decrease high density lipoprotein cholesterol. Reliable correlations were established in the lipid profile of the blood of the examined, and reliable relationships were determined between the indicators of atherogenic dyslipidemia and anthropometric measurements, which indicates an increased risk of lipid metabolic disturbances in individuals with abdominal obesity. Conclusions. The results will help to focus the attention of practitioners regarding atherogenic dyslipidemia in adolescents with obesity and signs of metabolic syndrome, as well as contribute to early therapeutic intervention and prevention of consequences. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local ethics committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the author. Key words: adolescents, metabolic syndrome, dyslipidemia.
Introduction: "Do Not Try to Remember": Pedagogy in Transition
Authors: Newman Winifred , Fithian Lee
Published: March 2022

This introductory section of the "Do Not Try to Remember": Pedagogy in Transition portion of the Schools of Thought proceedings contains an overview of the session's chairs, its themes, and included papers.
Reviewing Digital--Critiquing the Static Crit
Authors: Scelsa Jonathan
Published: March 2022

This paper focuses on challenging design pedagogy to question its ingrained reviewing methods that require the production of static media. This examination looks at new methods of digital design practice that allow a student to both design and quickly output a digitally interactive version of their model for impactful means of collaboration by faculty of all ages as well as other students. Topics covered include the space of digital review, how architectural academia can harness new social media culture, and core concepts surrounding the technologies of information.
Androgenic ability and plant regeneration potential in some tomato varieties
Authors: BĂDULESCU Adriana , DUMITRU Anamaria M. , MANOLESCU Andreea E. , SUMEDREA Dorin I. , POPESCU Carmen F.
Published: March 2022

Aiming to evaluate the in vitro regeneration potential, five varieties of tomatoes (Solanum lycopersicum) were studied for their response in anther culture. Anther explants at an early stage of microspore development were inoculated onto three culture media. The first differentiation processes were recorded during the first three weeks of culture, in darkness. The statistical analysis of the data recorded during the anther culture showed significant differences between genotypes regarding their specific response to culture conditions and the significant influence of the initiation medium composition in triggering the differentiation processes. Under the tested conditions were induced: the embryogenic potential in three genotypes (ʻȘtefănești 22ʼ, ʻCostate 21ʼ and ʻChihlimbarʼ) and the indirect organogenesis in two genotypes (ʻArgeș 20ʼ and ʻCostate 21ʼ). Morphological characteristics of anther-derived plants from ʻArgeș 20ʼ variety, grown in greenhouse conditions (growth rate, features of leaf,  flower, and fruit), as well as analyses with nine SSR markers (banding patterns, the coefficient of genetic similarity, and the polymorphism information content) in DNA samples from each regenerant and the donor variety, provided clear evidence of the occurrence of spontaneous genetic variation during in vitro anther culture, and of the existence of somaclonal variation in regenerated plants. The amplified products obtained with SSR primers revealed a total number of scorable bands of 160 and a mean percentage of polymorphic bands of 21.09%. Two out of the nine tested primers, SSR63 and SLM6-7 proved to be efficient in detecting genetic differences not only among regenerants but also between them and the donor genotype.
Extraction and characterization of mucilage from Opuntia ficus-indica cultivated on hydroponic system
Authors: LUNA-SOSA Brenda , MARTÍNEZ-ÁVILA Guillermo C.G. , RODRÍGUEZ-FUENTES Humberto , PASTRANA Lorenzo M. , AZEVEDO Ana G. , GONZÁLEZ-SANDOVAL Dulce C. , CERQUEIRA Miguel A. , ROJAS Romeo
Published: March 2022

An interesting component of Opuntia ficus-indica is the mucilage for its properties and industrial uses. However, the great variability of its quantity and quality caused by different growing conditions, the hydroponic system is an alternative. The objective of the present study was cultivating 4 species of Mexican Nopal in a hydroponic system, extract and characterize the mucilage. The characterization consists of pH, ºBrix, colour, proximal analysis, phenols, antioxidant activity, crystallinity, and chemical bonding constituents. ‘Copena F1’ is the best alternative for production of biomass and mucilage. ‘Villanueva’ had high levels of phenols (1,311.83 mg GAE g-1), antioxidant capacity ABTS·+ (6,301.12 mg TE g-1) and FRAP (536.26 mg GAE g-1). A large amount of lipids (1.39%), and nitrogen-free extract (49.27%). The functional groups of the mucilage were identified (-OH, -CH, -CH2, -CH3, C=C, HCH, -CHO) and gypsum, cellulose, SiO2 CaSO4, C2H2K2O5, CaCO3 and CaH2 by X-ray diffraction. The hydroponic system is a viable alternative for production of nopal and mucilage of high-quality mucilage that can be used in several sectors of the industry.
Combined use of compost, compost tea, and vermicompost tea improves soil properties, and growth, yield, and quality of (Allium cepa L.)
Authors: EL-SHAIENY Abdel-Haleem A. H. , FARRAG Hosny M. , BAKR Abeer A. A. , ABDELRASHEED Khaled G.
Published: March 2022

Liquid organic fertilizers are organic solutions that are a valuable choice for sustainable agriculture. In addition, these organic forms play a significant role, in integrated waste management strategies. In this study, a one-way analysis of variance, Pearson correlations and principal component analysis were performed on all traits, to compare the responses of sole application of compost, compost tea, vermicompost tea and their combinations on growth, yield of Allium cepa and on soil properties. The results showed that, in most cases with fertilizers treatments, the soil pH, CaCO3 and bulk density were decreased, while soil organic matter, total N, available P and K were increased. A mixture of 50% compost, 25% compost tea, and 25% vermicompost had more desirable effect on plant height, leaves number, plant fresh weight and plant dry weight. Therefore, application of 50% compost tea and 50% vermicompost tea, it is possible to achieve an acceptable total bulb yield ton/ha, total soluble solids %, and dry matter %. While, available P, K in soil and P % in plant were raised when plants treated with teas sole or combined with compost 50%. Using a mixture of 50% compost, 25% compost tea, and 25% vermicompost tea, was a higher nutrient concentration and had a significant impact on onion plants productivity, and on soil properties.
Impact of the foliar application of potassium nanofertilizer on biomass, yield, nitrogen assimilation and photosynthetic activity in green beans
Authors: MÁRQUEZ-PRIETO Ana K. , PALACIO-MÁRQUEZ Alejandro , SANCHEZ Esteban , MACIAS-LÓPEZ Bertha C. , PÉREZ-ÁLVAREZ Sandra , VILLALOBOS-CANO Octavio , PRECIADO-RANGEL Pablo
Published: March 2022

The agricultural areas of the world face problems that create difficulties when producing food and the excessive use of fertilizers is generating a negative environmental impact. An alternative that appears as a solution to this problem is the use of nanofertilizers. Within nanofertilizers an area of opportunity is the application of macronutrients, which report an increase in absorption efficiency of 19% compared to conventional fertilizers. Potassium (K) is one of the three macronutrients most used in agriculture and its deficiency affects key processes in plant development, limiting crop production. However, the number of publications where K is used as a nanofertilizer is limited, despite this, products in this form are already on the market. Therefore, the aim of this research work was to study the effect of the foliar application of K nanofertilizer on biomass, yield, nitrogen assimilation and photosynthetic activity in green beans cv. ‘Strike’. K was applied in the form of a nanofertilizer in doses of 0, 50, 100 and 200 ppm. The biomass accumulation, yield, nitrate reductase enzyme activity, photosynthetic activity and photosynthetic pigments were evaluated. The dose of 100 ppm of K nanofertilizer obtained a higher accumulation of biomass, nitrate reductase activity, photosynthetic activity, SPAD values and total chlorophyll content. While the 200-ppm dose obtained a higher increase in yield. The results obtained suggest that the application of K nanofertilizers benefits the physiological development of plants. However, more studies are required to compare the application of nanofertilizers with traditional fertilizers.