bluuebunny/crossref_metadata_2025 huggingface dataset:
Integráció vagy különnevelés? Szülői döntést befolyásoló tényezők autizmussal élő gyermekek oktatási formájának kiválasztásában
Authors: Koltai Borbála Gabriella , Stefanik Krisztina , Győri Miklós
Published: January 2022

Háttér és célok: Az autizmus multidimenzionális spektrumán a viselkedéses képet és a kognitív profilt egyénen belüli és egyének közötti nagyfokú heterogenitás jellemzi. Ezért az autizmussal élő gyermekeknek egyénre szabott, komplex, autizmusspecifikus oktatási ellátásra/támogatásra van szükségük. Ez integrált vagy különnevelésben is megvalósulhat, mindkettőnek vannak potenciális előnyei és kockázatai. Jelen tanulmány fő célja megismerni autizmussal élő iskoláskorú gyermekek szüleinek döntési tényezőit az integrált vagy különnevelés vonatkozásában.
Módszer: A nemzetközi szakirodalmat áttekintő tanulmányunk a PRISMA kritériumrendszerén alapul. Több keresőszó kombinációjának eredményeként a Web of Science és az ERIC nemzetközi adatbázisában, és egy folyóiratban összesen 548 kezdeti keresési találatot kaptunk. A beválogatási és kizárási kritériumok alapján, a cím, absztrakt majd a teljes szöveg vizsgálata során 13 releváns publikációt találtunk, melyeket részletesen áttekintettünk.
Eredmények: A szülőket döntésükben főként autizmussal élő gyermekük általuk észlelt egyedi igényei és boldogsága vezérli. A sok bizonytalanságot és komoly distresszt jelentő döntési folyamatban a szülők korlátozottan tapasztalják meg saját ágenciájukat és a partneri együttműködést a szakemberekkel. A választáshoz szükséges információk erősen korlátozottak, ezért az informális források szerepe hangsúlyos.
Következtetések: A nemzetközi áttekintés alapján is kulcsfontosságú lenne a szülők szakszerű informálása, az együttműködésen alapuló, az autizmussal élő gyermeket is bevonó iskolaválasztás és az inklúzió jelenlegi feltételeinek további javítása. A téma nemzetközileg is alulkutatott, pedig elengedhetetlen lenne mélyebben megismerni a szülői döntések hátterét és a kurrens kutatási eredmények hatékonyabb kommunikálásával segíteni a választást.
Kulcsszavak: autizmus, többségi iskola, különnevelés, intézményválasztás, szülői döntési tényezők
Patentes em Energias Renováveis: Un estudo exploratório a partir de indicadores para países selecionados
Authors: Fortes Storti Dienifer Regina , Martinelli Junior Orlando
Published: January 2022

Este artigo quantifica e analisa os esforços tecnológicos, os perfis de especialização e os movimentos tecnológicos em energias renováveis dos vinte principais países consumidores de energia no período de 1992 a 2018. Utiliza-se uma base de patentes em treze áreas de energias renováveis para a construção de indicadores estruturais de inovação, índices de vantagem tecnológica revelada e aplicação do método shift-share. Os resultados mostraram que os Estados Unidos estiveram à frente da maioria dessas áreas, entretanto, os esforços inovativos mais dinâmicos foram os do Japão, Coreia do Sul e China. A análise shift-share indicou que os esforços tecnológicos dos países não focam em uma fonte energética alternativa, mas conectam-se a um leque mais amplo de tecnologias em energias renováveis.
INKLUSI KEUANGAN DAN LITERASI KEUANGAN TERHADAP KINERJA DAN KEBERLANJUTAN UMKM DISOLO RAYA
Authors: Kusuma Melia , Narulitasari Devi , Nurohman Yulfan Arif
Published: January 2022

Usaha Mikro Kecil dan Menengah (UMKM) mengalami berbagai macam persoalan pada masa pandemi covid-19. Adapun persoalan yang dihadapi oleh UMKM berkaitan dengan permodalan dan keberlanjutan usaha akibat adanya pembatasan kegiatan masyarakat yang berdampak terhadap penurunan tingkat pendapatan. Penelitian ini bertujuan untuk menguji pengaruh inklusi keuangan dan literasi keuangan terhadap kinerja usaha dan keberlanjutan UMKM di Solo Raya. Penelitian yang dilakukan menggunakan pendekatan kuantitatif dengan memberikan kuesioner kepada responden. Adapun teknik pengambilan sampel menggunakan purposive sampling dengan memberikan pertimbangan berupa responden UMKM di Solo Raya yang sudah berdiri lebih dari satu tahun dan masih aktif menjalankan usaha. Teknik analisa data yang dilakukan menggunakan Partial Least Square (PLS). Hasil pengujian menunjukan bahwa inklusi keuangan berpengaruh terhadap keberlanjutan usaha dan kinerja keuangan UMKM, serta literasi keuangan berpengaruh terhadap kinerja keuangan pada UMKM di Solo Raya. Sedangkan variablel literasi keuangan tidak berpengaruh terhadap keberlanjutan usaha pada UMKM di Solo Raya
Kết quả cắt khối tá tụy, vét hạch tiêu chuẩn điều trị các khối u vùng đầu tụy
Authors: Thành Lê Văn , Dương Triệu Triều , Quang Vũ Văn , Lực Đào Tấn , Lợi Lê Văn , Linh Hồ Văn , Tuấn Vũ Ngọc , Hiếu Lê Trung
Published: January 2022

Mục tiêu: Đánh giá kết quả gần và kết quả xa của phẫu thuật cắt khối tá tụy vét hạch tiêu chuẩn trong điều trị u vùng đầu tụy. Đối tượng và phương pháp: Nghiên cứu mô tả tiến cứu, được thực hiện trên những bệnh nhân được chẩn đoán u vùng đầu tụy và được phẫu thuật cắt khối tá tụy vét hạch tiêu chuẩn từ tháng 6/2015 đến tháng 6/2020 tại Bệnh viện Trung ương Quân đội 108. Kết quả: 173 trường hợp được cắt khối tá tụy vét hạch tiêu chuẩn với độ tuổi trung bình 60,3 ± 8 tuổi. Triệu chứng hay gặp nhất là vàng da (82,7%), tỷ lệ phẫu thuật ở bệnh nhân lành tính là 14,6%, số hạch vét được trung bình là 12,9 ± 5,2 hạch, tỷ lệ di căn hạch là 44,7%. Thời gian phẫu thuật trung bình là 229,4 ± 42,5 phút, tử vong phẫu thuật 3,5%, thời gian nằm viện sau mổ trung bình 14,9 ± 6,5 ngày. Các biến chứng sau mổ hay gặp bao gồm: Rò tụy (20,8%), chảy máu tiêu hóa (13,9%), chảy máu trong ổ bụng (9,2%) và chậm lưu thông dạ dày ruột (8,1%). Thời gian sống trung bình sau mổ của nhóm bệnh nhân ung thư là 36 tháng, tỷ lệ sống sau mổ 3 năm và 5 năm lần lượt là 42,2% và 38,9%. Kết luận: Cắt khối tá tụy vét hạch tiêu chuẩn là kỹ thuật an toàn tương đối và hiệu quả trong điều trị các bệnh lý vùng đầu tụy.
Micromolecular inhibitors of superoxide radicals
Authors:   Nicolae Testemitanu State University of Medicine and Pharmacy, Replublic of Moldova, Andronache Lilia , Pantea Valeriana ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Replublic of Moldova, Gulea Aurelian ,   Moldova State University, Svet Inna ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Replublic of Moldova, Graur Vasilii ,   Moldova State University, Matcovschi Valerii ,   Institute of Neurology and Neurosurgery, Republic of Moldova, Gamaniuc Marina ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Replublic of Moldova, Gudumac Valentin ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Replublic of Moldova
Published: January 2022

Background: Currently, there is a growing interest in new copper (Cu2+) heterocyclic coordination compounds (CC), isothiosemicarbazide derivates, which demonstrated multiple beneficial properties, but their effect on reactions with free radicals such as the superoxide radical has not been investigated. Material and methods: The action of new micromolecular complexes of copper (Cu2+) chloride and bromide with methyl n- (prop-2-en-1-yl) -2- (pyridin2-ylmethylidene) hydrazine carbimidothioate on capturing activity of the superoxide radical was determined by the spectrophotometric method in vitro experiments. Results: It was established that the micromolecular complexes of copper (II) chloride and bromide with methyl n-(prop-2-en-1-yl)-2-(pyridin-2- ylmethylidene) hydrazine carbimidothioate have been found to possess strong superoxide radical inhibitor properties when interacting with a superoxide radical. In addition to this, the IC50 of the studied compounds depends on the nature of the acid-ligand in the internal sphere of the complex and increases in the following sequence: Cl- –Br- . Conclusions: The established property of mentioned compounds is new, because their use as micromolecular inhibitors of superoxide radicals has not been described so far. The synthesized CC expand the arsenal of superoxide radical inhibitors with high biological activity. Their possible significance for the development of new treatment strategies for diseases associated with the overproduction of superoxide radicals is discussed.
Cercadão dos Dicetas e a educação popular quilombola
Authors: Thé Raul da Fonseca Silva , Arnaud Paiva Indra Lucena
Published: January 2022

O presente artigo busca compreender os processos de educação popular desenvolvidos pela Comunidade Remanescente Quilombola (CRQ) – situada no município de Caucaia, no estado do Ceará – Cercadão dos Dicetas. De modo a apresentar a formulação das aprendizagens, das experiências e dos conhecimentos socialmente partilhados. Para tanto, se elaborou uma pesquisa eminentemente qualitativa, baseada em observações diretas, em entrevistas e rodas de conversas. Além de encaminhar uma investigação histórica como base de discussão enquanto se procura aprofundá-la com um mergulho empírico. O debate teórico se articula com uma observação sobre o reconhecimento em suas dimensões histórica, de raça e de classe, sem deixar de pontuar os processos de construção de identidades, que perpassam todo o processo de educação popular quilombola, tendo tanto os encontros comunitários quanto a educação escolar o foco central no ensino e nos sujeitos e nas suas vivências. Como considerações finais, observamos como a comunidade interpreta suas condições e propõe suas reivindicações de modo a resistir através da educação e como o processo educativo popular apresenta tanto limites, próprios e a ele impostos, quanto possibilidades.
قياس أثر مؤشرات الأداء في تحسين جودة الخدمات الصحية " دراسة تطبيقية على مديرية الشؤون الصحية - الطائف "
Authors: البقمي محمد سعد مسفر , Mozamil Ali Mohammad Osman
Published: January 2022

مستخلص الدراسة 
هدفت الدراسة الحالية إلى تسليط الضوء على أثر مؤشرات الأداء في تحسين جودة الخدمات الصحية في مديرية الشؤون الصحية بمحافظة الطائف من خلال معرفة إذا ما كانت تلك المؤشرات كافية من أجل تحقيق جودة تحسين الخدمات الصحية المقدمة.
واستخدم الباحث المنهج الوصفي التحليلي الذي يعتبر من أهم المناهج التي تستخدم وأكثرها استخداماً في البحوث فهو يُعتبر الأنسب لهذه الدراسة، وقد تَكَوَّن مجتمع الدراسة من منسوبي مديرية الشؤون الصحية بمحافظة الطائف والبالغ عددهم (1486)، كما تم استخدام أسلوب العينة العشوائية البسيطة ومكونة من (353) موظف وموظفة، وقد وجد الباحث أن الأداة الأكثر ملاءمة لتحقيق أهداف هذه الدراسة هي الاستبانة. وتوصلت الدراسة إلى النتائج التالية: ١- هناك موافقة بدرجة متوسطة بين أفراد الدراسة على مؤشرات الأداء وكذلك الرضا الوظيفي للعاملين، إضافة إلى تحقيق الأهداف والخطط الاستراتيجية للمديرية، وثبات مستوى الخدمات ورضا المراجعين. ٢-هناك موافقة بدرجة متوسطة بين أفراد الدراسة على أهمية مؤشرات الأداء وكذلك الاستفادة من كل القوى الكامنة للموارد البشرية فيها وتطويرها، إضافة إلى توفر البيئة التي تؤدي إلى المشاركة الكلية ببيئة العمل، وتدبير الموارد البشرية داخل المديرية بالشكل الأمثل. ٣-هناك تأثير واضح لمؤشرات الأداء على جودة الخدمات الصحية المقدمة. ٤-مستوى الأداء الوظيفي لدى العاملين جاء بمستوى متوسط. ٥-هناك علاقة طردية (إيجابية) ذات دلالة إحصائية بين التزام الإدارة العليا وقياس مؤشرات الأداء وتحسين جودة الخدمات الصحية.
التوصيات: ١-ضرورة الاستفادة من التغيرات التنظيمية الخاصة بالموارد البشرية المنفذة بالاعتماد على تكنولوجيا المعلومات في تعزيز الشفافية والوضوح في المهام والواجبات المختلفة للعاملين وبما يرفع من نوعية الأداء. ٢-الإفادة من توافر المعلومات الخاصة ببرامج التدريب المختلفة في تعزيز القدرات الفردية على العمل التعاوني والتشارك في أداء المهام بصورة بسيطة دون تعقيد. ٣-الاستفادة من توافر نظم تقييم الأداء الشمولية الإلكترونية في المديرية والتي تعكس جوانب الأداء المختلفة من حيث المعاير وآليات التقييم والقرارات الاستراتيجية المرتبطة في تعزيز قدرات العاملين المختلفة والخاصة بأداء الأعمال بعيداً عن التعقيد والتداخل والقيام بالأعمال غير الضرورية.
The Causative Organism of Urinary Tract Infections UTI: a Cross-sectional Study from a Tertiary Hospital In Saudi Arabia
Authors: Alwaladali Mohammed , Soufan Maya Talal , Almutairi Bandar
Published: January 2022

BACKGROUND: Urinary tract infections (UTIs) are a common disease with a high burden on the healthcare industry. A systematic exploration is necessary of the organisms that cause UTIs, to improve empirical management of patients with acute illness before culture results are obtained. The prevalence of these organisms, both in immunocompetent and immunocompromised patients in Saudi Arabia, needs further clarification.

METHODS: This is a cross-sectional analysis reviewing the charts of patients visiting the emergency department of, and those admitted to, a tertiary hospital in Saudi Arabia during the month of July-August 2021.

RESULT: The total number of participants was 199, with a mean age of 55.8 years (SD=20.02), ranging from 14 to 97 years. 61.8% of patients were immunocompromised, and one-third were from the oncology wards. 40.7% (n=81) were diabetics and 8.54% (n=17) had CKD/ESRD. Females were 25% more likely than males to acquire Candida infections, while Pseudomonas aeruginosa was 26.7% more prevalent in males. Nevertheless, mixed gram-negative bacteria caused the most UTIs, in 40.20% (n=80) of cases, followed by Candida, 16.1% (n=32), and then mixed gram-positive bacteria, in 14.57% (n=29). This was also observed among immunocompromised patients and the subsegment of oncology patients on active chemotherapy, although with variable percentages.

CONCLUSION: This study demonstrates that patients’ immune status is the main determinant of the causative organism of UTIs. The treatment threshold for Candida in diabetic patients and those with CKD/ESRD should be lower, especially when they require admission.
Effects of Not Intubating Non-Trauma Patients With Low Glasgow Coma Scale Scores: a Retrospective Study
Authors: Alsulimani Loui K , Baajlan Ohoud , Alghamdi Khalid , Alahmadi Raghad , Bakhsh Abdullah , Abualenain Jameel
Published: January 2022

Background: Endotracheal intubation (EI) is a critical life-saving procedure commonly performed on emergency department (ED) patients who present with altered mental status (AMS). 
Aims: We aimed to investigate the safety of observing, without EI, patients who present to the ED with decreased levels of consciousness (LOC). 
Methods: We reviewed the data of all adult ED patients with a Glasgow Coma Scale (GCS) score ≤ 8, during the period between 2012 and 2018, in an academic tertiary care centre. Trauma patients were excluded. The patients were divided into two groups for comparison: those who were intubated and those who were not. Data on mortality, morbidity, and baseline clinical characteristics were collected and analysed. 
Results: After screening 6334 electronic medical records of patients presenting to the ED with decreased LOC, only 257 patients met the inclusion criteria. 173 (67.3%) patients were intubated, while 84 (32.7%) were not. Among the intubated patients, 165 (95.4%) were intubated early (within two hours of presentation). Mortality, morbidity and length of stay for the intubated group were higher, although the baseline clinical characteristics were the same. 
Conclusion: It might be safe to observe non-trauma emergency patients with a GCS score ≤ 8 without intubation. However, such decision should be taken carefully, as delayed intubation can be associated with higher mortality and morbidity
Perdebatan Iman Dan Kufurnya Fir’aun Perspektif Mufasir Dan Sufistik
Authors: Saepudin  , Fauzi Umar
Published: January 2022

Pharaoh was a title for the king of ancient Egypt. Many of his stories are mentioned in the Qur'an, he is mentioned as a ruler who has bad attitudes, however, behind that the al-Qur'an explains that when he died, he had the opportunity to make his faith and Islam plausible. Then what is the state of faith that he offered? al-Khazin (2004) stated that the repentance of Pharaoh was not accepted by Allah SWT because at that time there was no more time to repent. In contrast to Dawani (W. 1512 AD), he stated that his repentance was accepted because he made a vow before the spirit reached the throat. If viewed from two conditions about faith, namely there is a pledge and justification in the heart (Ibrahim Mustafa, 1370 H), then Pharaoh has met these criteria. The author tries to analyze these two problems by using the interpretation method tafsir maudhȗ’i''. The faith made at the end of life is the closing of a good life, and the al-Qur'an explains the end of the life of Pharaoh by pledging to believe and surrender to Allah SWT (QS. Yȗnus / 10: 90).
Bullet Babies: The repeating nature of the medical hoax
Authors: Herr Harry
Published: January 2022

Introduction: Incredible tales of medical hoaxes associated with virgin births have been recounted through history. Some reports exist of wartime gunshot testicular injuries that caused pregnancy in a second bullet victim. This paper sought to identify the sources and circumstances of such tales and how similar legends appear to be perpetuated in medical historical lore. Sources: Medical journals, contemporary newspaper accounts, and archives of secondary lay-press magazines and periodicals. Results: The first known episode of a pregnancy conceived via bullet wound occurred in the American Civil War. A woman claimed to become pregnant from being shot by a bullet that had passed through the scrotum of a Civil War soldier. In reality, the tale had been fabricated by a doctor who wanted to tease his colleagues over their boastful surgical triumphs. A second such ‘bullet baby’ was reported in 1999 during the Bosnian conflict. The two episodes, despite their lack of medical credulity, were perpetuated in the medical press by reputable authorities. Conclusions: History sometimes offers a storyline that may be so fantastical that even medical authorities may either disregard its impossibility or unknowingly prolong its life.
Adrenaline Rush: the race for the crystallization of adrenal extracts by Takamine and Uenaka
Authors: Yamashima Tetsumori
Published: January 2022

Introduction: The adrenal gland was first described by Eustachio in 1564, but its physiologic role remained unknown for three centuries. In the late 1890’s, many researchers had directed their attention to the isolation of adrenal extracts, but all failed until the successful efforts of biochemists Jokichi Takamine and Keizo Uenaka. Takamine’s patents on Adrenalin were the first ever awarded for a hormone and he used his royalties to improve international relations between America and Japan. There is considerable controversy, however, in how adrenaline was first crystalized, where the work was done, and to whom the credit for its discovery is given. Sources and Methods: Published contemporary medical literature, newspaper archives, and publicly accessible research archives in Japan, Sweden, and the United States Results: Takamine was a multilingual businessman with a background in western and eastern medicine, a successful biochemist, and importer/exporter before he took on the project of isolating adrenaline. His successful patents and savvy business acumen allowed him to support innovative research in physiology. He hired Keizo Uenaka, who had experience with isolating ephedrine, to develop the critical methods required to crystallize adrenal extracts where other contemporaries, including Takamine, had failed. Takamine applied for and was awarded five immediate US patents for the discovery although he did not include Uenaka in that effort. Takamine co-founded the Nippon Club and the Japanese Society of New York, both of which ultimately survived the anti-Japanese fervor of the 1940s and, in 1912, worked to bring the gift of 3,000 Japanese Cherry Trees to Washington DC. The Japanese Patent Office honored Takamine as one of Japan’s 10 Great Inventors but it was only after Uenaka’s death in 1960, and the discovery of his laboratory manuals, was Uenaka’s full role in the discovery of adrenaline made known. Conclusions: Jokichi Takamine was an international benefactor and biochemist extraordinaire who, with Keizo Uenaka, was the first to crystallize adrenal medullary catechols. Takamine’s efforts saved lives and did much to engender a spirit of Japanese-American goodwill that persisted for decades.
Using textual volunteered geographic information to model nature-based activities: A case study from Aotearoa New Zealand
Authors: Egorova Ekaterina
Published: January 2022

A boom in volunteered geographic information has led to extensive data-driven exploration and modeling of places. While many studies have used such data to explore human-environment interaction in urban settings, few have investigated natural, non-urban settings. To address this gap, this study systematically explores the content of online reviews of nature-based recreation activities, and develops a fine-grained hierarchical model that includes 28 aspects grouped into three main domains: activity, settings, and emotions/cognition. It further demonstrates how the model can be used to explore the variation in recreation experiences across activities, setting the stage for the analysis of the spatio-temporal variations in recreation experiences in the future. Importantly, the study provides an annotated corpus that can be used as a training dataset for developing methods to automatically capture aspects of recreation experiences in texts.
Åse Gruda Skard og moderne barneoppdragelse
Authors: Kolle Tonje
Published: January 2022

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Drug related problems on anti-platelets and anti-coagulants in stroke
Authors: Mounika Thogaru
Published: January 2022

Introduction: Antiplatelet agents prevent platelets from dumping and prevent clots from forming and growing. Anticoagulants slow down clotting thereby reducing fibrin formation and preventing clots. Drug-related problems are a major concern in the view of physical, psychological, and economic burden to patients.

Objectives: The aim of the research work is to access, evaluate and monitor the drug-related problems on antiplatelet and anticoagulants in stroke patients. 

Methods: In this study 300 numbers of patients were screened including both males and females of all age groups in a super specialty hospital.

Results: The number of ADRs was found to be predominantly associated with a male as compared to females as well as most ADRs were reported for patients with cardiac stroke as compared to ischemic stroke and hemorrhagic stroke.

Conclusions: Low molecular weight heparins, aspirin, clopidogrel drugs resulted in various adverse drug reactions. Mostly 114 cases of ADR were due to drug-drug interactions followed by drug-food interactions and drug ethanol interactions as was concluded from the study.
Risk-benefit associated with azithromycin: A brief review
Authors: Pradhan Anil Kumar , Nahak Ajit , Mohapatra Gyanendra Narayan
Published: January 2022

Introductions: Azithromycin is the most popular prescribed antimicrobial agent around the world. It comes under the class of macrolide antibiotics. Because of its higher efficacy, tolerance, and broad-spectrum activity, it is primarily used in upper and lower respiratory tract infections, some sexually transmitted infections, and major bacterial infections.

Methods: Pieces of literature were reviewed to access the risk and benefits associated with azithromycin.

Results: Generally, this is commercially available in solids, liquids, and ophthalmic formulations due to its minimal adverse events. It is also used in the case of COVID-19 drug therapy due to its pharmacological and therapeutic properties.

Conclusions: The review of literature presented that it may increase the risk of cardiac death, hepatic injury, ototoxicity, hypersensitivity reactions.
As dimensões do ensino de Geografia da Saúde no Brasil
Authors: Porto Bruno , Gurgel Helen , Catão Rafael
Published: January 2022

Contexto: a geografia da saúde é uma área de pesquisa que se torna cada dia mais importante, especialmente no Brasil onde a presença de um sistema único de saúde é tema de muitas pesquisas. De modo a conhecer a abrangência do ensino de Geografia e Saúde nos cursos de geografia, foi realizado um estudo para avaliar a disponibilidade de disciplinas sobre essa temática nas universidades públicas brasileiras. Para tal, foi elaborado e enviado aos coordenadores dos cursos de geografia um questionário online e foi realizada entrevistas abertas com professores da área da saúde sobre a utilização da geografia em suas aulas. Resultados:  apenas cerca de um terço dos cursos possuem uma disciplina na temática de geografia da saúde, e elas tendem a ser de caráter optativo e não possuir oferta frequente. Além disso, professores da área de saúde afirmaram que utilizam técnicas e saberes de geografia da saúde, mas não conheciam essa temática de pesquisa, pelo menos não por esse nome. Conclusões: apensar do aumento de estudos nessa temática ainda há uma importante lacuna no ensino da geografia da saúde no Brasil, provavelmente devido abaixa institucionalização e divulgação dessa temática. Portanto, recomenda-se um esforço na divulgação e institucionalização dessa temática a partir da oferta de disciplinas e ações de interação da geográfica com cursos da área da saúde.
PENDAMPINGAN PENGOLAHAN PANGAN DAN PENGEMASAN PRODUK BAGI PELAKU USAHA MIKRO KECIL DAN MENENGAH (UMKM) BIDANG PANGAN DI KECAMATAN BUA KABUPATEN LUWU
Authors: Nurasia Nurasia , Hidayat Rahmat , Al Anshori Fitrah
Published: January 2022

Kegiatan Pendampingan Pengolahan Pangan dan Pengemasan Produk bagi Pelaku Usaha Mikro Kecil dan Menengah (UMKM) Bidang Pangan di Kecamatan Bua Kabupaten Luwu bertujuan untuk memberikan pemahaman kepada pelaku UMKM khususnya di bidang pangan terkait pentingnya pengolahan pangan yang baik serta pengemasan produk yang baik sehingga dapat meningkatkan minat konsumen. Kegiatan ini dilaksanakan selama 2bulan secara luring dan daring. Kegiatan luring berupa pelatihan dan pendampingan pengolahan produk yang memenuhi standar Cara Pengolahan Prodak Pangan yang Baik-Industri Rumah Tangga (CPPB-IRT) berdasarkan standar yang ditemtukan oleh Badan Pengawasan Obat dan Makanan (BPOM). Kegiatan dilanjutkan dengan pelatihan mengenai cara pengemasan prodak yang baik sehingga dapat meningkatkan minta konsumen yang dapat memberikan dampak positif terhadap peningkatan pendapatan bagi pelaku UMKM. Adapun kegiatan daring yang direncanakan berupa pendampingan dan pembinanaan kepada para peserta melalui WA Group. Adapun hasil yang diharapkan dari kegiatan ini adalah berupa kemasan produk pangan dari pelaku UMKM yang siap dipasarkan, serta jurnal pengabdian yang diteribkan di jurnal nasional serta sertifikat HKI.
ENGLISH TRAINING WITH DRILLS AND REPETITION FOR SIMPURSIA VILLAGE CORAL CADETS
Authors: Satriani Satriani , Hasbi Muhammad
Published: January 2022

The service team provides solutions based on the results of an analysis of the situation and problems faced by partners to increase opportunities for youth members to be immediately accepted to work after completing their education at vocational high schools. In terms of the solution's form, namely training and mentoring for youth members to practice spoken English using the drilling and repetition method, the results obtained at the end of this service were: (1) positive and enthusiastic response from members of the youth organization; (2) increased awareness of the importance of spoken English proficiency; (3) willingness to take risks in order to participate; (4) increased spoken English vocabulary, grammar, and pronunciation; (5) greater access to recorded voices of foreign speakers; and (6) more opportunities to practice speaking English in dynamic and enjoyable (but not monotonous) settings. (7) the availability of foreign speakers' voices in the form of mp3 recordings; (8) in their spare time, members of the youth organization are encouraged to listen to foreign speakers' voices, imitate them, and practice independently; and (9) after the training and mentoring is completed, the future availability of online sites for accessing and downloading learning media files.
User Perception on The Waste Utilization in The Upcycled Garden Design at Taman Samudera, Seri Manjung Perak
Authors: Adnan Nurhidayah Assyahadah , Mazlan Maizura
Published: January 2022

Many cities becoming unsustainable due to the massive volumes of unrecycled municipal garbage that end up in suburban landfills. Our culture, on the other hand, appears to be generating trash in an almost inevitable manner. However, in the recent years, the merits of using salvaged and upcycled materials are started to be addressed in the landscape design and recently arose in the hardscape construction. This highlights the importance of educating people, raising awareness and promoting a better way of dealing with solid waste. Based on studies conducted in Taman Samudera, Seri Manjung, Perak, this paper attempts to analyze the user perception on the waste utilization for the upcycled garden design. This quantitative research was conducted in two phases; Phase 1; to study the user awareness, user acceptance and user preference on the upcycling hardscape and Phase 2; to propose a landscape master plan of the upcycled garden. The respondent (n=92) involved in this study are the residents of Taman Samudera, Seri Manjung, Perak. It shows that most of the respondents were aware and accepted the use of recycled materials in the upcycled garden. The finding indicates that the highest mean score for preferred recycled material used for hardscape construction were plastic bottles, tyres, and Compact Discs were suitable to be included in the master plan of the upcycled garden. The proposed Upcycled Garden at Taman Samudera, Seri Manjung, Perak will be a valuable recreational area that is environmental friendly while educating the public tackling the serious issues of poor recycling rates and waste management in Malaysia.
PHARMACOGNOSTIC STANDARDIZATION OF JACARANDA MIMOSIFOLIA LEAVES AND STEM BARK
Authors: Patrakar R. G. , Bhusnure O. G. ,   CRPS, Nanded Pharmacy College, Nanded - 431 602, Maharashtra, India
Published: January 2022

pharmacognostic standardization is a basic criterion to assure authenticity and quality of any medicinal plant. In the present study micromorphological examinations along with proximate analysis, fluorescence and elemental analysis of Jacaranda mimosifolia leaves and stem bark were carried out. Morphological examination indicated compound, bipinnate and alternately arranged leaves having several pairs of leaflets. The leaflets were oblong ellipsoidal in shape with parallel venation, acute apex and entire margin. The stem bark was concavely curved, greyish brown colored with conical shaped buds on the surface. Microscopic examination of leaves presented dorsiventral lamina, unicellular pointed trichomes, vascular bundle, collenchyma tissues and calcium oxalate crystals while bark indicated cork, stone cells, lignified fibres, calcium oxalate prisms, starch grains and medullary rays. Elemental analysis revealed the presence of aluminum, chlorides and iron in leaves and bark of Jacaranda mimosifolia. The present study will assist as an important source of information in identification and further investigation of this plant.
IN VITRO ANTI-INFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT AND DIFFERENT FRACTIONS OF CENTELLA ASIATICA LEAVES BY PROTEIN DENATURATION
Authors: Sharma S , Trivedi R. , Choudhary N. K. ,   Department of Pharmacology, B R Nahata College of Pharmacy, Mhow Neemuch Road, Mandsaur, 458001, MP, India
Published: January 2022

Inflammation might be a complex organic reaction to a hazardous stimulant such as pathogens, or injured tissues and mainly causes itching, swelling, skin redness, warm and slight pain. Herbal drugs are widespread in India for their effectiveness, easy availability at low cost and provide low toxicity as compared to modern drugs. Centella asiatica is one of the oldest Ayurvedic medicinal plants, used in treatment of various skin diseases. The aim of our present research was to evaluate the in vitro anti-inflammatory activity of methanolic extract and different fractions of C. asiatica leaves. In protein denaturation method, the percentage inhibition for methanolic extract was observed to be 40.22%. The petroleum ether and n-butanol fraction of methanolic extract of C. asiatica were observed to exhibits 54.12 and 44.42% inhibition, respectively. Diclofenac sodium was used as a standard drug. In comparison with other fractions petroleum ether and n-butanol fractions showed best activity. The preliminary phytochemical studies of n-butanol fractions and n-butanol fractions showed the presence of terpenoids, flavonoids etc., which are used in the treatment of inflammation. Thus, we can call the latter as intense anti-inflammatory agent.
EFFECT OF ESCULETIN ON OSSIFICATION OF NOTOCHORD OF ZEBRAFISH LARVAE AND AMPUTATED CAUDAL FIN OF ZEBRAFISH ADULTS
Authors: Pherwani P. U , Sathaye S ,   Institute of Chemical Technology (ICT), Nathalal Parekh Marg, Matunga, Mumbai - 400 019, Maharashtra , India
Published: January 2022

Esculetin, a natural coumarin, has anti-osteoclastic activity on cell line. We studied the effect of esculetin in vivo. Zebra fish larvae were raised in water containing various concentrations of esculetin. The area and intensity of ossified notochord was measured. Toxicity study of esculetin on adult zebra fish was performed. The caudal fin of zebrafish was amputated and the fishes were exposed to various concentrations of esculetin. Area of the regenerated fin was found to be measured. The intensity of mineralization of zebra fish larvae was significantly more with 10μg/mL esculetin. Esculetin was safe upto 100mg/L. The area of the regenerated fin was not statistically significant amongst the different groups. Esculetin showed significant increased osteogenesis in zebrafish larvae. Further investigation is needed as the study has certain innate limitations.
DEVELOPMENT AND VALIDATION OF RP HPLC METHOD FOR THE ESTIMATION OF SOFOSBUVIR IN BULK, TABLET AND INDUSTRIAL WASTE WATER
Authors: Dhanunjayachary V , Likhitha V.L.S. , Vijaya Sri K. , Madhuri M. A ,   Department of Pharmaceutical Analysis, Malla Reddy College of Pharmacy (Affiliated to Osman ia University) Maisammaguda, Secunderabad - 500 100, Hyderabad, Telangana, India
Published: January 2022

The study was aimed at development and validation of RP-HPLC method for estimation of sofosbuvir in bulk, pharmaceutical dosage form and pharmaceutical industrial waste. The chromatographic separation was performed on Agilent Syncronis C 18 (100 mm × 4.6 mm, 5μm) column, with a mobile phase comprising of a mixture of methanol: acetonitrile: water (45:30:25 v/v/V). The flow rate was 1.0 mL/min with detection at 260 nm. Retention time of sofosbuvir was found to be 2.040 min. As per ICH guidelines, the method was validated for linearity, accuracy, limit of detection, limit of quantitation, precision, robustness and system suitability. Linearity was found to be in the range of 4-24 μg/mL with regression equation y = 675284.x + 49120 and correlation coefficient 0.999. The low % RSD values indicate the method to be accurate and precise. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.046 and 0.1400 μg/mL, respectively. The % recovery of tablets was found to be in the range of 99.9– 101.3%. It can be concluded that this validated HPLC method is easy, precise, accurate, sensitive and selective for estimation of sofosbuvir in bulk, tablet and applicable for analyses of in pharmaceutical industrial waste.
WATER AS A GREEN SOLVENT: A REALITY CHECK
Authors:   General Manager, R&D.,  Divis Laboratories Limited, Hyderabad, India., Rao M.N.A.
Published: January 2022

Dear Reader, Water has been perceived as a green solvent due to its non-toxic and noninflammable nature and it is believed that its use usually makes a synthetic process more economical than using other organic solvents. A few years ago, we developed a new process where water was used as a solvent at the final stage. We labeled the process as a “green process” with a great sense of achievement since we had replaced a Class II organic solvent used in the prior art, with water. A few months later, the production team asked us if they could substitute water with an organic solvent. We were surprised and explained our lofty reasons of saving the Good earth from pollution. The practical scientists in the manufacturing plant informed us that to distill a large volume of water at low temperature consumed too much power and the process was highly energy intense. So eventually, a green process had unwillingingly turned grey!
EXTRACTION, ISOLATION, CHEMICAL IDENTIFICATION AND IN VITRO UROLITHIATIC ACTIVITY OF PIPERINE FROM PIPER NIGRUM
Authors: Jyoti  , Murti Yogesh , Agrawal Krishn K. ,   Department of Pharmaceutics, School of Pharmaceutical Sciences, Maharishi University of Information Technology, Lucknow-226 013, (U.P.), India
Published: January 2022

Piper nigrum is belongs to the family Piperaceae. The aim of the present study was to extract, isolate and investigate in vitro urolithiatic activity of alkaloid (piperine) from black pepper and identification by chemical reagents. In vitro urolithiatic evaluation of piperine was performed by percentage dissolution and turbidity methods. Calcium oxalate crystals were synthetically prepared and packed in a semipermeable membrane in both methods. Results were compared statistically and it showed significant P​
The method of discretization signals to minimize the fallibility of information recovery
Authors: Laptiev Oleksandr , Yevseiev Serhii , Hatsenko Larysa , Daki Olena , Ivanenko Vitaliy , Fedunov Valery , Hohoniants Spartak
Published: January 2022

The paper proposes a fundamentally new approach to the formulation of the problem of optimizing the discretization interval (frequency). The well-known traditional methods of restoring an analog signal from its discrete implementations consist of sequentially solving two problems: restoring the output signal from a discrete signal at the output of a digital block and restoring the input signal of an analog block from its output signal. However, this approach leads to methodical fallibility caused by interpolation when solving the first problem and by regularizing the equation when solving the second problem. The aim of the work is to develop a method for the signal discretization to minimize the fallibility of information recovery to determine the optimal discretization frequency.The proposed method for determining the optimal discretization rate makes it possible to exclude both components of the methodological fallibility in recovering information about the input signal. This was achieved due to the fact that to solve the reconstruction problem, instead of the known equation, a relation is used that connects the input signal of the analog block with the output discrete signal of the digital block.The proposed relation is devoid of instabilities inherent in the well-known equation. Therefore, when solving it, neither interpolation nor regularization is required, which means that there are no components of the methodological fallibility caused by the indicated operations. In addition, the proposed ratio provides a joint consideration of the properties of the interference in the output signal of the digital block and the frequency properties of the transforming operator, which allows minimizing the fallibility in restoring the input signal of the analog block and determining the optimal discretization frequency.A widespread contradiction in the field of signal information recovery from its discrete values has been investigated. A decrease in the discretization frequency below the optimal one leads to an increase in the approximation fallibility and the loss of some information about the input signal of the analog-to-digital signal processing device. At the same time, unjustified overestimation of the discretization rate, complicating the technical implementation of the device, is not useful, since not only does it not increase the information about the input signal, but, if necessary, its restoration leads to its decrease due to the increase in the effect of noise in the output signal on the recovery accuracy. input signal. The proposed method for signal discretization based on the minimum information recovery fallibility to determine the optimal discretization rate allows us to solve this contradiction.
Enhanced Epileptic Seizure diagnosis using EEG Signals with Support vector machine and Bagging Classifiers
Authors: Alrawashdeh Rana , Al-Fawa'reh Mohammad , Mardini Wail
Published: January 2022

Many approaches have been proposed using Electroencephalogram (EEG) to detect epilepsy seizures in their early stages. Epilepsy seizure is a severe neurological disease. Practitioners continue to rely on manual testing of EEG signals. Artificial intelligence (AI) and Machine Learning (ML) can effectively deal with this problem. ML can be used to classify EEG signals employing feature extraction techniques. This work focuses on automated detection for epilepsy seizures using ML techniques. Various algorithms are investigated, such as  Bagging, Decision Tree (DT), Adaboost, Support vector machine (SVM), K-nearest neighbors(KNN), Artificial neural network(ANN), Naïve Bayes, and Random Forest (RF) to distinguish injected signals from normal ones with high accuracy. In this work, 54 Discrete wavelet transforms (DWTs) are used for feature extraction, and the similarity distance is applied to identify the most powerful features. The features are then selected to form the features matrix. The matrix is subsequently used to train ML. The proposed approach is evaluated through different metrics such as F-measure, precision, accuracy, and Recall. The experimental results show that the SVM and Bagging classifiers in some data set combinations, outperforming all other classifiers
Estate, Capital and Province in the Alexander Potyomkin’s novel Man is canceled (2007)
Authors: Bogdanova Olga
Published: January 2022

The article analyzes the novel of the modern Russian writer A. Potyomkin Man is canceled (2007), which received a wide public response. The main idea of the work is the need for a radical change of the “mass man” of the turn of the XX-XXI centuries at the psychosomatic level. The ideological and compositional center is the specially built Rimushkino estate in the Oryol province, where the serf spirit of the Russian Empire at the turn of the XVIII-XIX centuries is reproduced. To answer the question of why the estate space of Russia is becoming the most representative field for anthropological experiments of the beginning of the XXI century, we consider the estate neo-myths of the Silver Age (the lost paradise on earth) and the Soviet period (the camp hell living in the mentality), as well as the imperial-colonial concept of the postmodern era (the estate as a frontier in the process of class-oriented internal colonization of the country). The multidimensional semiotics of the estate sets a new relationship between “metropolitan” and “provincial” concerning the other loci of the novel.
Comparative Study of Intestinal Parasitic Infection among Pregnant and Non-Pregnant Women in Owerri, Nigeria: A Case Study of the Federal Medical Centre, Owerri
Authors:   Department of Histopathology, Federal Medical Center (FMC), Owerri, Imo State, Nigeria., Babatunde Olaleye W. , Awah I.J. ,   Department of Medical Parasitology, School of Medical Laboratory Sciences, University of Port-Harcourt Teaching Hospital, Port-Harcourt, Rivers State, Nigeria., Babatunde Abosede A. ,   Department of Histopathology, Federal Medical Center (FMC), Owerri, Imo State, Nigeria.
Published: January 2022

A survey of intestinal parasites of pregnant and non-pregnant women attending the Federal Medical Centre, Owerri, Imo State, Nigeria was carried out between November 2010 and April 2011. A total of 300 samples (150 from pregnant women and 150 from non – pregnant women respectively) were randomly collected from these women who attended the hospital. The samples were examined using the direct wet preparation and formol ether concentration technique. A total of 41 (13.67%) women were infected. The infected stool samples contained eggs of Ascaris lumbricoides (48.78%), Hookworm (39.02%), and Cysts of Entamoeba histolytica (12.20%). Although, more pregnant women (16(39.02%)), the difference was not statistically significant. The highest prevalence of 20% was observed in the pregnant women within the age – group of 27-30 while the age group of 19-22 years. The difference between the prevalence of infection in the age group was significant. However personal hygiene improved health education programs and supervised public toilets together with food vendor's education have been recommended as measures to eradicate intestinal parasitic infections among pregnant and non-pregnant women. It has been recommended that stool analysis should be part of the antenatal screening tests particularly in subjects with a high level of parasitemia.
Floristic Analysis of Cultivated Plants of Rajasthan, India
Authors: Singhadiya M. , Pandey R.
Published: January 2022

The present paper deals with 789 cultivated plants, in which dicots 671 species and monocots 118 species were collected from gardens, cultivated fields, parks, along roadsides planted as an avenue trees and adjoining forests areas of the Rajasthan state.
Apparel Recommendation Engine Using Inverse Document Frequency and Weighted Average Word2vec
Authors:   Postgraduate, School of Computer, University of Exeter, England,  UK, K Parvesh ,   Computer Science and Engineering, Panimalar Engineering College, Chennai ,600123,  India,   Professor, Department of Computer Science and Engineering, Karpagam College of Engineering , Coimbatore 641032, India., C Tharun , M Prakash
Published: January 2022

The rapid development of e-commerce shopping marketplaces necessitates the use of recommendation engines and quick, precise, and efficient algorithms in order for the company's business models to generate a massive amount of profit. A computer vision software programme enables a computer to learn a great deal from digital images or movies. Machine learning methods are used in computer vision, and several machine learning techniques have been developed specifically for this purpose. Information retrieval is the process of extracting useful information from a dataset, and computer vision is the most commonly used tool for this purpose nowadays. This project consists of a series of modules that run sequentially to retrieve information from a marked area on a receipt. A receipt image is used as an input for the model, and the model first uses various image processing algorithms to clean the data, after which the pre-processed data is applied to machine learning algorithms to produce better results, and the result is a string of numerical digits including the decimal point. The program's accuracy is primarily determined by the image quality or pixel density, and it is necessary to ensure that an input receipt is not damaged and content is not blurred.
Effect of lunar cycle on rainfall
Authors: RAJAN C. K. , G. BINDU
Published: January 2022

ABSTRACT. Rainfall data for a period of 50 years from 1931 onwards have been analysed for three west, coast stations in Kerala for the southwest monsoon period, The period is divided into two halves, the first half, i.e.June-July, providing comparatively more rainfall  and the second half, i.e. August-September, providing comparatively lesser rainfall. Rainy days, having rain amounts>6.25 cm/day, have only been utilized for this study. The lunar cycle, which is having 29.53 days, is divided into ten phases, each phase constituting of around three days. To consider the effect of solar activity, the period is divided into active and quiet sun by considering those years with sunspot number greater than the upper quartile and those with sunspot number less than the lower quartile respectively. The data were analysed using x2 test. It describes the magnitude of the discrepancy between theory and observation.

Analysis has shown that there is some statistical significance between heavy rainfall and lunar cycle. The effect is more significant in active sun period which shows the effect of solar activity also.