bluuebunny/crossref_metadata_2025 huggingface dataset:
Hand grip strengthening exercises on fine motor skills in children with autism spectrum disorder
Authors: Mohandass G. , Muthusamy Rajeswari , Ramachandran Sivakumar
Published: April 2023

Background. Movement impairments in autism spectrum disorder (ASD) are manifested as both delays and deficits, with delays found in gross motor, fine motor and speech domains and deficits found in coordination, postural control and gait. Functional fine motor task is dependent on hand grip strength (HGS) which is found to be decreased. Therapeutic strategies focus primarily on sensory integration issues but HGS is not comprehensively addressed in improving fine motor skills (FMS).
Objective. The aim of the study was to analyse the effect of hand grip strengthening exercises on improving FMS in children with ASD.
Materials and Methods. This interventional study was carried out in 27 children with ASD who were recruited from Vidya sudha – Centre for children with special needs. After including in the study, level of FMS was assessed by Peabody Developmental Motor Scale (PDMS-2) and HGS was quantified with Martin Vigorimeter. Control group received conventional therapy and Intervention group received hand grip strengthening exercises along with routine therapy for duration of 6 weeks and HGS and level of FMS were reassessed with same outcome measures.
Results. Paired t test showed statistically significant change of HGS in Intervention group and FMS of both the group with p < 0.05. Unpaired t test showed statistically significant change of HGS and FMS with p < 0.05 in Interventional group compared to control group.
Conclusion. Hand grip strengthening exercises improves the HGS and has positive effect on FMS which can be included in the standard plan of care in rehabilitating children with ASD.
Management of giant-cell arteritis in Switzerland: an online national survey
Authors: Iudici Michele , Hemmig Andrea Katharina , Stegert Mihaela , Courvoisier Courvoisier , Adler Sabine , Becker Mike Oliver , Berger Christoph T. , Dan Diana , Finckh Axel , Mahr Alfred , Neumann Thomas , Reichenbach Stephan , Ribi Camillo , Seitz Luca , Villiger Peter , Wildi Lukas , Daikeler Thomas , On behalf of Giant Cell Arteritis SCQM Study Group
Published: April 2023

AIMS OF THE STUDY: To assess current practices in diagnosing, treating, and following-up giant-cell arteritis by specialists in Switzerland and to identify the main barriers to using diagnostic tools.

METHODS: We performed a national survey of specialists potentially caring for patients with giant-cell arteritis. The survey was sent by email to all members of the Swiss Societies of Rheumatology and for Allergy and Immunology. A reminder was sent to nonresponders after 4 and 12 weeks. Its questions covered the following dimensions: respondents’ main characteristics, diagnosis, treatment, and imaging’s role during follow-up. The main study results were summarized using descriptive statistics.

RESULTS: Ninety-one specialists, primarily aged 46–65 years (n = 53/89; 59%), working in academic or nonacademic hospitals or private practice, and treating a median of 7.5 (interquartile range [IQR]: 3–12) patients with giant-cell arteritis per year participated in this survey. Ultrasound of temporal arteries/large vessels (n = 75/90; 83%) and positron-emission-tomography-computed tomography (n = 52/91; 57%) or magnetic resonance imaging (n = 46/90; 51%) of the aorta/extracranial arteries were the most common techniques used to diagnose giant-cell arteritis with cranial or large vessel involvement, respectively. Most participants reported a short time to obtain imaging tests or arterial biopsy. The glucocorticoid tapering scheme, glucocorticoid-sparing agent, and glucocorticoid-sparing treatment duration varied among the participants. Most physicians did not follow a predefined repeat imaging scheme for follow-up and mainly relied on structural changes (vascular thickening, stenosis, or dilatation) to drive treatment choice.

CONCLUSIONS: This survey indicates that imaging and temporal biopsy are rapidly accessible for diagnosing giant-cell arteritis in Switzerland but highlights heterogeneous practice in many disease management areas.
Urheberrechtsschutz digitaler Alltagsspuren
Authors: Lennartz Jannis , Kraetzig Viktoria
Published: April 2023

Das Urheberrecht meidet qualitative Wertungen bei der Bestimmung des Werkbegriffs. Die Schöpfungshöhe für ein Werk wird dafür erstens interpretativ gebeugt, zweitens werden dem Werk mit Leistungsschutzrechten legislativ kleine Geschwister beigegeben – so den Lichtbild- und Filmwerken die ebenfalls geschützten Licht- und Laufbilder. Die Erweiterung der Schutzobjekte führt gemessen am Anspruch von §§ 1, 2 UrhG zu einem überschießenden Schutz. Ein Gesetz, welches dem Schutze „persönlicher geistiger Schöpfungen“ der „Literatur, Wissenschaft und Kunst“ dienen soll, behandelt Schnappschüsse wie große Kunst. Dies wird durch die Digitalisierung immer problematischer: Zum einen führt die vereinfachte Herstellung von Licht- und Laufbildern zu ihrer ungehörigen Vermehrung und Verwendung in digitaler Kommunikation. Zum anderen fällt der Aufwand als Kriterium für die Anerkennung eines Werks oder einer Leistung als schützenswert weg. Ohne die alten technischen Grenzen müssen Juristen ihre Arbeit machen: den Werkbegriff qualitativer verstehen und der Anwendung des Urheberrechts jenseits seiner Grenzen skeptisch gegenüberstehen. Der Urheberrechtsschutz sollte digitale Alltagsspuren nicht umfassen.
Patient Safety in Emergency Medical Services
Authors: R. Wilson Bryan , Woodrow Ashley
Published: April 2023

Patients deserve high-quality, evidence-based care delivered from the moment they call for help to the moment they are safely delivered to the hospital. Often patient safety is not viewed as a fun or exciting topic by prehospital clinicians, but it need not be a burden. A culture of safety in emergency medical services can enhance patient outcomes and improve the overall safety in a community. The design and structure of the ambulance are the first layer of protection for patients. Couple that with ambulance operations topics, such as speed and light and siren use and that covers a large swath of the patient safety engineered into the system. There are patient-focused topics such as medication safety protocols, structured handoffs, and competency assessments of high-risk procedures that all serve to increase patient safety. Lastly, an emergency medical services clinician-oriented topic that also heavily impacts our patients is fatigue mitigation. Actively addressing fatigue and employing fatigue mitigation strategies can be used to enhance the safety of patients and will likely enhance the experience of prehospital clinicians in the organization.
Improving Mindfulness, Quality of Life, and Controlling Cellular Aging through Meditation
Authors: Namika Dasanayaka Nirodhi , Dushyanthi Sirisena Nirmala , Samaranayake Nilakshi
Published: April 2023

Many people suffer from stress and anxiety due to complex lifestyles. Stress is one of the main causes of various diseases. In addition, it causes a lower level of consciousness, quality of life, and a higher rate of cellular aging. Meditation becomes a trending topic to overcome these problems. Key terms including “Meditation,” “Mindfulness,” “Quality of life,” “Telomere,” and “Telomerase” were used to search literature in PubMed, Medline, and Google scholar databases. Meditation is cheap, viable, and simple mental training. Several studies have been conducted on the effects of meditation on well-being, including mindfulness level, quality of life, and cellular aging. Accordingly, many of these studies suggest that meditation practice can improve well-being and may help control cellular aging. Though meditation showed various physiological and psychological benefits, the mechanism behind the meditation and these benefits still remains unclear. However, by reducing a person’s stress level, meditation can improve mindfulness, develop quality of life, and reduce cellular aging.
Congenital Malformations of the Outer, Middle, Inner Ear and Cochlear Nerve with Favorable Cochlear Implantation
Authors: V. Toropchina Liia , I. Zelikovich Elena
Published: April 2023

This case study presents the neuroradiological findings of two deaf children with CHARGE syndrome and oculo-auriculo-vertebral spectrum disease. Both patients had rare combinations of ear and auditory nerve anomalies associated with a high risk of intra- and postoperative complications during cochlear implantation (CI) and poor results. However, CI was carried out with favorable results in terms of hearing and speech development. When determining indications for CI in children with complex anomalies, it is necessary to assess the state of all ear structures in computed tomography of the temporal bones and MR (3 Tesla) images. The most critical is the state of the following structures: cochlea—modiolus—cochlear aperture—diameter of the internal auditory canal—the presence and condition of the auditory nerve. In the presence of a normal or dysplastic cochlea, a hypoplastic auditory nerve is not a contraindication for CI. In this situation, the presence of a modiolus and at least partially open cochlear aperture are prognostically favorable. In the presence of a large or small common cavity, an undivided vestibulocochlear nerve is not considered a contraindication for CI. Such a combination—a common cavity and an undivided vestibulocochlear nerve—is a prognostically quite favorable option.
Molecular Histopathology and Cytopathology in Cardiovascular Diseases
Authors: Viet Duc Dang , Thanh Huy Nguyen , Quoc Quy Tran , Tat Tho Nguyen
Published: April 2023

In this chapter, we describe the most deadly heart diseases, including the fourth parts: Anatomy of the heart, chronic coronary syndrome and acute coronary syndrome and STEMI, Cardiomyopathy, and Pulmonary embolism. The written structure of a component includes Abstract, Pathophysiology, Clinical diagnostic criteria, histopathology, and cytopathology. The content is summarized based on the recommendations of the American Heart Association and the European Society of Cardiology. All images in this chapter are data at our center. In the chapter, we will see the relationship between histopathology and cytopathology and pathophysiology, which will serve as a basis for us to have more studies in the future.
Preprint of Obstetrics and Gynecology Articles During and After the COVID-19 Pandemic
Authors: Keikha Fatemeh , Salari Yalda , Salari Yasaman , Ghaemi Marjan
Published: April 2023

: In this report, a brief historical overview of preprints focuses on the impact of the COVID-19 pandemic on the distribution of preprints in obstetrics and gynecology, and the benefits and drawbacks of preprints are described. Preprints are manuscripts that are published before peer review. They are widely available even though they are recent in biomedical science. The COVID-19 pandemic enhanced the number of preprints prominently. It is known that 5% of all preprint articles issued during the pandemic were in obstetrics and gynecology. Some benefits include the increased pace of being available and the exposure rate. Also, it provides an opportunity to check for plagiarism and prevent malpractice earlier. Challenges to the distribution of preprints also exist, such as the potential lack of quality, premature data, and the possibility of misguiding normal people. Given the high importance of data release in obstetrics and gynecology, both the authors and the publishers should regulate strict yet rational guidelines before letting the information become widely accessible.
The Effects of Cup Feeding and Finger Feeding Techniques on Weight Gain in Preterm Infants Admitted to the Neonatal Intensive Care Unit
Authors: Mirzaei Fatemeh , Kerman Saravi Fatihe , Naderifar Mahin , Mahmoodi Nasrin
Published: April 2023

Background: Weight is one of the main indicators of physical growth and brain development in infants, especially preterm infants. Feeding preterm infants is an ongoing challenge for those in charge of feeding infants, especially those with very low birth weights. Feeding difficulties in premature infants lead to long hospital stays and increased costs. Objectives: This study aimed to compare the effects of cup feeding and finger feeding techniques on weight gain in premature infants. Methods: This randomized clinical trial study was conducted on 90 premature infants with an average weight of 1784.3 ± 497 g admitted to the neonatal intensive care unit (NICU) of Ali Bin Abi Talib (AS) Hospital located in Zahedan, the southeast of Iran, in 2021. The infants were randomly divided into 3 groups: Cup feeding, finger feeding, and control groups (each with 30 infants). The intervention was performed for 3 consecutive days without interruption, even on holidays for each infant. The amount and frequency of feeding each infant depended on the birth weight and the diagnosis of a specialist. The infant’s weight was recorded before and after the intervention. Data analysis was performed using SPSS version 22 using analysis of variance (ANOVA), paired-samples t-test, and chi-square test. Results: The average weight of infants significantly increased in the cup feeding (P < 0.01) and finger feeding (P < 0.01) groups compared with the control group. The highest weight gain was recorded in the finger feeding group (109.55 g), followed by the cup feeding group (65.8 g) and the control group (31.1 g; P = 0.001). The ANOVA results suggested that the finger feeding technique was most effective in gaining weight and achieving independent oral feeding in premature infants.
Ihmisen sosiaalisuuden alkulähteillä – Westermarckilainen sosiologia ja sosiaaliantropologia
Authors: Pipatti Otto
Published: April 2023

Ensimmäinen kokonaisesitys westermarckilaisesta sosiologiasta ja sosiaaliantropologiasta, jotka hallitsivat suomalaista yhteiskuntatutkimusta ennen toista maailmansotaa. Edvard Westermarck (1862–1939) on kautta aikain tunnetuin suomalaistutkija. Hänen kansainvälisesti menestyneet oppilaansa julkaisivat teoksiaan johtavilla brittiläisillä kustantajilla. Kirja avaa Westermarckin ja hänen oppilaidensa lähtökohtia valistusfilosofiassa, evoluutioajattelun eri suuntauksissa ja antropologiassa. Lisäksi se luo kokonaiskuvan westermarckilaisten tutkimusaiheista ja keskinäisistä samankaltaisuuksista ja eroista. Westermarck ja hänen oppilaansa tutkivat sosiaalisten ilmiöiden alkuperää, joka synnyttää ja ylläpitää niitä yhä tänäkin päivänä. Samalla heitä yhdisti kiinnostus sellaisiin käyttäytymistaipumuksiin, jotka ihminen jakaa muiden eläinten kanssa. Suomalaisen sosiologian historia on usein hahmotettu ”vanhan” ja ”modernin” sosiologian välisenä erontekona, jossa vanhentuneet teoriat ja metodit korvautuivat toisen maailmansodan jälkeen uudenlaisilla lähestymistavoilla. Kirja tarkastelee tätä kehityskertomusta kriittisessä valossa ja osoittaa westermarckilaisen perinnön pysyvän arvon nykypäivän tieteellisissä ja yhteiskunnallisissa keskusteluissa.
TÍNH KHẢ THI VÀ AN TOÀN CỦA KỸ THUẬT MỞ ĐƯỜNG VÀO ĐỘNG MẠCH QUAY ĐOẠN XA ĐỂ CHỤP VÀ CAN THIỆP ĐỘNG MẠCH VÀNH
Authors: Đinh Huỳnh Linh , Nguyễn Ngọc Quang
Published: April 2023

Mục tiêu: Đánh giá tính khả thi và an toàn trong chụp, can thiệp động mạch vành (ĐMV) qua đường vào đoạn xa động mạch quay.

Đối tượng và phương pháp: 90 bệnh nhân có chỉ định chụp và can thiệp ĐMV qua da được sử dụng đường vào đoạn xa động mạch quay tại Viện Tim Mạch - Bệnh viện Bạch Mai, từ tháng 8 năm 2020 đến tháng 10 năm 2021.

Kết quả: Tuổi trung bình: 68,04 ± 9,75 tuổi, tỉ lệ nam/nữ: 2/1. Chỉ định chụp ĐMV: chủ yếu là hội chứng vành cấp (78,9%), trong đó nhồi máu cơ tim cấp có ST chênh lên chiếm 13,3%. Tỷ lệ thành công của thủ thuật mở đường vào đoạn xa động mạch quay là 94,5%. Không có biến chứng tại chỗ trong và sau can thiệp.

Kết luận: Mở đường vào động mạch quay đoạn xa để chụp và can thiệp ĐMV kỹ thuật có tính khả thi, tính ứng dụng và an toàn cao.
CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN CAN THO: CLINICAL CHARACTERISTICS AND FEATURES OF TREATMENT BY CLINICAL PHENOTYPES
Authors: Vo Pham Minh Thu , Dinh Chi Thien , Vo Thi Kim Hoang , Nguyen Thi Thu Thao , Tran Xuan Quynh , Tran Trong Anh Tuan , Nguyen Thi Hong Tran , Duong Thi Thanh Van , Nguyen The Bao , Cao Thi My Thuy
Published: April 2023

Background: phenotypic approach in the treatment of COPD is lacking in general medical facilities, despite the importance of this data. Objectives: The study aimed to identify divergences in features, pharmacologic regimens of COPD by clinical phenotypes in the real-life context of care units in Can Tho City that manage outpatients with chronic respiratory diseases. Materials and methods: a prospective cohort study was carried out. We enrolled 158 patients who met the sampling criteria for this study. Data collected include (1) biometric characteristics, (2) medical history, (3) characteristics of COPD (including: symptoms, chest radiograph, peripheral blood eosinophil count, pulmonary ventilation parameters, bronchodilator test, and pharmacological regimen). COPD were classified into three phenotypic groups according to the criteria of the 2017 Spanish guideline (GesEPOC) and were also categorized into four groups (ABCD) according to the 2019 GOLD guideline. Results: the clinical AE phenotype was predominant at 41.8%, whereas the NON-AE and ACO was 38.6% and 19.6%. According to the GOLD, classifying as group A, B, C, D is 19%, 34.8%, 10.1%, and 36.1%, respectively. Between the different phenotypic groups, there were a variety of variances in the eosinophil count of the peripheral blood, but there were no changes in some kinds of chest radiograph images. Response-to-bronchodilator-test rate was higher in the ACO phenotype than in the NON-AE and the AE phenotypes. All ACO patients who received LABA/ICS. The proportion of using LABA/ICS accounted for most NON-AE and AE patients. Conclusions: among clinical phenotypes, the AE phenotype accounted for the highest percentage. There were differences in the clinical characteristics among phenotypes. ICS using is popular among COPD patients.
EVALUATION OF THE EFFECTIVENESS OF ORAL AND VAGINAL MISOPROSTOL FOR INTRAUTERINE FETAL DEATH AND FETAL ANOMALY IN SECOND TRIMESTER PREGNANCY TERMINATION: A RANDOMIZED CLINICAL TRIAL
Authors: Duong My Linh , Pham Van Linh , Bui Quang Nghia , Nguyen Thi Hue , Duong Thi Khao Ry , Ngo Ngoc Ha
Published: April 2023

Background: which method of the expulsion of intrauterine fetal death and fetal anomaly in second trimester is effective, safe, and suitable for pregnant women. Objectives: to evaluate the effectiveness of oral misoprostol and vaginal misoprostol for intrauterine fetal death and fetal anomaly in second trimester pregnancy termination. Materials and Methods: a clinical trial in 108 women experiencing intrauterine fetal death and fetal anomaly during the second trimester in the obstetric department, Can Tho central general hospital in 2014. Excluded criteria: multiple pregnancies, uterus cesarean section scar, and misoprostol contraindication. Intervention: randomized division into two groups: group 1: misoprostol oral, group 2: vaginal misoprostol; dosage as recommended by FIGO. Success was defined as a complete and natural fetal and placenta expulsion without dilation and curettage or other treatment; and healthy hospital discharge. Results: the success rate of group 1 was 75.9%; group 2 was 83.3%. The success rates for fetal conditions of intrauterine fetal death were 74.6%, and the fetal anomaly was 86.7%. In group 1, the success rate in intrauterine fetal death was 63%, fetal anomaly was 88.9%. In group 2, the success rate in intrauterine fetal death was 81.3% and fetal anomaly was 86.4%. The rate of expulsion in the first 24 hours was 78.1% in group 1; 88.9% in group 2, which was not different statistically. Some side effects encountered in the study such as headache, nausea, diarrhea, fever/chills, rash were mainly seen in the oral misoprostol group; all side effects and complications were mild and transient. Related factors to complete expulsion in both groups were gestational age, parity, and fetal conditions. Conclusion: vaginal misoprostol has the same effectiveness and fewer complications than oral misoprostol.
KNOWLEDGE OF CONTRACEPTION AND SAFE SEX AMONG STUDENTS AT CANTHO UNIVERSITY OF MEDICINE AND PHARMACY, VIET NAM
Authors: Nguyen Phuc Hong Ngoc , Nguyen Quoc Tuan , Ba Tho Ngoc Chuyen , Le Dai Khanh Duy , Nguyen Thi Cam Tien , Nguyen Thuy Duong
Published: April 2023

Background: Viet Nam was one of the countries with the highest abortion rate in the world, of which about 70% were of the adolescents. Nowadays, students at Can Tho University of Medicine and Pharmacy are facing many problems related to reproductive health such as unwanted pregnancy, abortion, sexually transmitted diseases, homosexuality... Objectives: To determine the proportion of medical students at Can Tho University of Medicine and Pharmacy have correct knowledge about contraceptive methods and safe sex and its related factors. Materials and methods: A cross-sectional descriptive study with analysis was carried out on 370 first-year, second-year and third-year general medicine students who were studying at Can Tho University of Medicine and Pharmacy at the age of 18-24. Results: The results showed that the rates of students had a high knowlege of contraception and practicing safe sex were 8.38% and 28.65% respectively. The statistically significant factors include: For students with high knowledge about contraception: having already taken a Reproductive Health module, learning from internet by themselves and  joining Union/Association activities; For students with high knowledge about safe sex: having a hometown in an urban area; learning from newspaper and books, home schooling, friends and general knowledges. Conclusion: Students’ knowledge about contraceptive methods was not good. Students' knowledge about safe sex was quite good. Related factors to high knowledge about contraception and safe sex of students: having already taken a Reproductive Health module, having a hometown in an urban area, joining Union/Association activities, learning from internet, newspaper and books, home schooling, friends and general knowledges.
ERP-Systeme in der Ära des Cloud Computing
Authors: Schütte Reinhard
Published: April 2023

ERP-Systeme haben eine lange Historie und sind technologisch nicht immer auf dem aktuellen Stand. In diesem Beitrag wird skizziert, welche betriebswirtschaftlichen und technologischen Herausforderungen die Zukunft dominieren werden und welche Implikationen dies für die Entwicklung von ERP-Systemen haben wird.
Experiencia de prohibición del consumo de tabaco en una unidad de psiquiatría en tiempos de pandemia
Authors: López López Carla , Freijeiro Llorca Ana
Published: April 2023

Introducción. Los objetivos de este trabajo fueron evaluar el grado de dependencia tabáquica de los pacientes ingresados en el servicio de psiquiatría de un hospital de tercer nivel y relatar la experiencia vivida por los pacientes los primeros meses de la prohibición de fumar en la Unidad de Hospitalización de Psiquiatría de dicho hospital. Metodología. Se realizó un estudio con enfoque cuantitativo y cualitativo en el que se administró el test de Fagerström y se realizaron entrevistas semiestructuradas a 47 pacientes seleccionados mediante muestreo no probabilístico por conveniencia. Resultados. De los pacientes encuestados, 32 participantes usaron parche durante su ingreso hospitalario. No fue necesario utilizar un método de contención más allá de la verbal o de la farmacológica. Manifestaron tener una dependencia alta al tabaco en el Test de Fagerström 22 participantes. El parche de nicotina se consideró un método eficaz. Además, se encontraron otras estrategias efectivas para afrontar los síntomas de la abstinencia tabáquica. Las incidencias relacionadas con el cese del consumo fueron puntales. Discusión. No hay motivo que justifique mantener el hábito tabáquico en una unidad de hospitalización psiquiátrica. Puede que el retraso en la implementación de esta medida venga motivado por el estigma hacia los pacientes con problemas de salud mental que sigue presente dentro de los propios sanitarios.
 
ABSTRACT
Introduction. The objectives of this study were to assess the degree of tobacco dependence of patients admitted to the psychiatry service of a third-level hospital and to report the experience lived by the patients during the first months of the smoking ban in the Psychiatric Hospitalization Unit of this hospital. Methodology. A study with a quantitative and qualitative approach was conducted using the Fagerström test and semi-structured interviews with 47 patients selected by non-probabilistic convenience sampling. Results. Among the patients surveyed, 32 participants used the nicotine patch during their hospital stay. It was not necessary to use a restraint method other than verbal or pharmacological. A high dependence on tobacco in the Fagerström Test was reported by 22 participants. The nicotine patch was considered an effective method. In addition, other effective strategies were found to deal with the symptoms of smoking withdrawal. Incidents related to the cessation of consumption were punctual. Discussion. There is no reason that justifies maintaining the smoking habit in a psychiatric hospitalization unit. The delay in the implementation of this measure may be motivated by the stigma towards patients with mental health problems that are still present among the health professionals themselves.
Regulatory Environmental Impact, Contract Law, Intellectual Property Rights, and Taxation of Entrepreneurial Activities in Bandung City
Authors: Cahyaningrum Anis Okta , Permana Riko Mersandro , Rukmana Arief Yanto , Suroso  , Fachrurazi
Published: April 2023

This study investigates the regulatory environment impacting entrepreneurial activities in Bandung City, focusing on environmental impact, contract law, intellectual property rights, and taxation. The study employs a mixed-methods approach, including a survey of 100 entrepreneurs and interviews with key stakeholders. The results indicate that entrepreneurs in Bandung City face significant challenges in complying with environmental impact regulations, protecting their intellectual property rights, and navigating the complex tax system.These challenges can significantly impact the success of entrepreneurial activities and discourage entrepreneurship in the region. The study identifies several strategies for supporting entrepreneurial activities in Bandung City, including improving the clarity and consistency of regulations, enhancing awareness and understanding of intellectual property rights, and simplifying the tax system. Policymakers could also explore other strategies, such as providing training and support for entrepreneurs on regulatory compliance and intellectual property management. The study highlights the need for policymakers to balance the benefits of regulation with the potential burdens on entrepreneurial activities and adopt a more entrepreneurial mindset in designing policies that support innovation and economic growth.
Linkages between Social Media Presence, Brand Awareness, Customer Loyalty, and Sales Growth in Entrepreneurial Companies (Study on Fashion Industry Entrepreneurs in West Java)
Authors: Sudirjo Frans , Titing Andry Stepahnie , Radnan Yokie , Yodiansyah Hefri
Published: April 2023

This study aimed to investigate the relationship between social media presence, brand awareness, customer loyalty, and sales growth among fashion industry entrepreneurs in West Java. A survey was conducted with 150 participants, and the data were analyzed using Pearson’s correlation coefficient. The results indicate that social media presence is positively associated with brand awareness, customer loyalty, and sales growth. The findings suggest that fashion industry entrepreneurs in West Java should focus on building and maintaining a solid social media presence to improve their brand awareness, customer loyalty, and sales growth.
Agreement of total corneal power measured by CASIA 2, Pentacam AXL, and IOLMaster 700 in normal and keratoconic patients
Authors:   , Yodying Rusaporn
Published: April 2023

Purpose: To evaluate agreement of total corneal power (TCP), ocular biometry and IOL power calculation measured by CASIA 2, Pentacam AXL, and IOLMaster 700 in normal and keratoconic patients Setting: King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand Design: Prospective observational study Methods: One-hundred normal eyes and 34 keratoconic eyes were enrolled. Biometric values were measured by each device for three times by two operators to evaluate repeatability and reproducibility of TCP and other parameters. The agreement of TCP and other parameters including total corneal astigmatism, anterior keratometry, anterior corneal astigmatism, posterior keratometry, posterior corneal astigmatism, anterior chamber depth, white-to-white (WTW) corneal diameter, central corneal thickness, and intraocular power were evaluated. Intraclass correlation coefficient and Bland Altman plot was used to analyze. Results: The repeatability and reproducibility of TCP and other biometry were high in all devices except WTW (ICC > 0.9). The agreement of TCP was excellent among three devices in both groups (ICC > 0.9). However, the agreement of TCP between CASIA 2 and IOLMaster 700 was slightly lower in normal eyes (ICC = 0.867) and keratoconic eyes (ICC = 0.852) with mean differences more than 1.0 diopter, might be considered clinically significant.  Wider 95% limit of agreement were found in keratoconus group. Most of the other parameters and IOL power showed good to excellent agreement except WTW showing poor to moderate agreement in both groups.  Conclusions: The agreement of TCP by CASIA 2, Pentacam AXL, and IOLMaster 700 was excellent in normal and keratoconic eyes. However, TCP cannot be used interchangeably.
Techno-economic analysis of acetaldehyde production via partial oxidative dehydrogenation of ethanol
Authors:   , Sompong Sudarat
Published: April 2023

Due to the increased attention regarding the battery electric vehicles, the demand for ethanol as a biofuel may be reduced in the future. Therefore, ethanol transformation towards acetaldehyde is conducted in this work, primarily because of the higher selling price and several advantages of acetaldehyde. Regarding the acetaldehyde preparation, acetaldehyde is produced by partial oxidative dehydrogenation of ethanol.

According to the economic analysis results, at the same price of acetaldehyde, an annual production capacity of 120,000 tons is the most profitable production size. In addition, the potential process of producing acetaldehyde from ethanol is acetaldehyde production process at 200°C since this process offers a shorter POP and a higher IRR compared to another process, namely acetaldehyde production process at 300°C. For energy consumption, the process performed at temperature of 200°C requires more thermal utilities than that of 300°C. This is because the low conversion of ethanol. For the same reason, the CO2 emissions in the case of operating at 200°C are also higher. Regarding the usage of electric utilities, the process performed at 300°C consumes the higher amount of electricity since a gas compressor is used in the process. The existence of this compressor is one of the reasons that makes this process less profitable.
Sustainability assessment of power production by chemical looping combustion
Authors:   , Uraisakul Watchara
Published: April 2023

This study investigated the chemical looping combustion (CLC) process improvement for power production from energy management, system hydrodynamics, and sustainability perspectives. In the first part, the 3k factorial design was used for systematically investigating the operating variables that affect the thermal efficiency of the CLC combined with the humid air gas turbine (HAT) cycle. A set of operating variables, A) pressure of the air reactor, B) air compressor stages number, C) air compression methods, and D) air flow rate, were explored. The result showed that the highest thermal efficiency was at 55.87 % when operated at (A) 15 atm, (B) 7 stages, (C) method 3, and (D) 61,000 kmol/hr. Moreover, the efficiency could be improved further to 57.67% by increasing the Ni loading to 28% (by weight). The second part, the dual circulating fluidized bed reactor (DCFBR), was selected for the CLC system and investigated its operation by 2-D computational fluid dynamics (CFD) simulation. For the solid fuel, the result showed that the low value of temperature and ratio of coal velocity to the weight of an oxygen carrier provided the best performance. For the gaseous fuel, the high pre-exponential factor, the low initial solid volume fraction, velocity, and CH4 mass fraction in feed increased temperature and conversion. The result also indicated that the operating conditions are crucial for suitable hydrodynamics achievement and the CO2 capture efficiency. In the last part, three analyses, which were energy performance, economics, and sustainability, were evaluated to identify the best case by enhancing the process sustainability. Six case studies have been investigated the effects of the combustion types (conventional combustion (CC) and CLC) and system configuration (CO2 capture stages and operating conditions). According to emergy analysis, which is the tool that gives a more holistic view of the solution than the others, Case 4 was the best case due to its emergy sustainability index (ESI), when local content was taken into consideration. However, Case 5 would be the best case from a global perspective.
Electrochemical paper-based immunosensor for biomarkers detection
Authors:   , Boonkaew Suchanat
Published: April 2023

This dissertation focused on the development of electrochemical paper-based immunosensor for determining essential biomarkers by using a label-free immunoassay. This dissertation can be divided into four main parts. In the first part, an origami paper-based analytical device (oPAD) was developed for c-reactive protein (CRP) detection. oPAD was designed to combine the preparation of immunosensor and detection step into a single device. A gold nanoparticle modified graphene screen-printed carbon electrode (AuNPs/G/SPCE) was utilized to enhance the sensitivity of the electrode. The developed sensor was successfully applied to determine CRP in a certified serum sample. For the second part, an electrochemical paper-based analytical device (ePAD) was created for simultaneous determination of three crucial cardiovascular disease (CVD) biomarkers including CRP, troponin I (cTnI), and procalcitonin (PCT). The proposed ePAD has multiple detection zones and multiple working electrodes, which could enable simultaneous three biomarkers in a single sample with high sensitivity and selectivity. For the third part, a simple and low-cost ePAD immunosensor for ferritin determination was reported. The ePAD was custom designed on the filter paper to successfully fabricate an immunosensor. The working electrode was first modified with graphene oxide (GO) using an inkjet-printing technique to enhance the reproducibility of the electrode. The ePAD was finally applied in a practical sample, giving results that are in agreement with the standard method. Lastly, an ePAD was architecturally designed for simultaneous detection of hepatitis B (HBV) and hepatitis C core antigen (HCV). The fast-flow and delayed channels were created to control the flow velocity on an ePAD device. To validate the sensor performance, the developed immunosensor was applied to measure the known amount of HBV and HCV in the serum samples. All developed immunosensors provided good performances for biological and clinical diagnosis and allowed for further development of an advanced platform.
Anti-oxidant and anti-inflammatory compounds from Magnolia liliifera (L.) Baill. flower and dendrobium signatum Rchb.f.
Authors:   , Khumploy Prajak
Published: April 2023

In this study, a purification of the EtOAc crude extract of Dendrobium signatum Rchb.f. aerial parts was performed fifteen compounds (1-15) and the hexane crude extracts of Magnolia liliiferra (L.) Baill. were further isolated to accomplish three compounds (16-18). They yielded one new picrotoxane sesquiterpene, 7-hydroxydendroterpene B (2) and a new a-pyrone, (-)-6R-signatone (4), along with sixteen known compounds. These included dendroxine (1), crystallinin (3), dendrocandin B (5), dendrocandin I (6), 6''-de-O-methyldendrofindlaphenol A (7), p-hydroxyphenylethyl-p-coumarate (8), 3,4-dihydroxy-5,4'-dimethoxybibenzyl (9), 3-methoxy-5-[2-(4-methoxyphenyl) ethyl]phenol (10), 4,4'-dihydroxy-3,5-dimethoxybibenzyl (11), naringenin (12), (2S)-homoeridodictyol (13), (2S)-homohesperetin (14), (-)-syringaresinol (15), (+) sesamin (16), (+) fargesin (17) and (-) kobusin (18). Their structures of new compounds were elucidated through by analysis of spectroscopic data and single-crystal X-ray diffraction analysis, whereas those of the known ones were identified by comparison of their data in the literature. Afterward, all the extracted isolated compounds were evaluated for antioxidant activity using the DPPH and ABTS free radical scavenging assay. The results showed that the new (-)-6R-signatone 4 exhibited very promising ABTS scavenging activity with IC50 of 0.71 ± 0.01 µM in comparison with a positive control Trolox® (IC50 of 27.26 ± 0.33 µM). Furthermore, the dimer bibenzyls (5-7) along with compounds 3. 4, 8, 9 and 17 were promising to inhibit the lipid peroxidation in range (53-70 %) in the vital model at concentration 5 µM. For the anti-inflammatory activity, among all the compounds, it was found that lignans, (-) kobusin 18 (IC50 of 4.72 ± 0.17 µM) significantly enhanced the NO production inhibition activity. Similarly, phenylpropanoids, p-hydroxyphenylethyl-p-coumarate 8 also displayed the high potent inhibition with IC50 of 6.18 ± 0.50 µM as compared to the standard indomethacin (IC50 of 28.42 ± 3.51 µM).
Design and synthesis of modified chitosan/collagen coated-gold nanoparticles as a carrier for anticancer and antiinflammatory agents
Authors:   , Hongsa Naruthai
Published: April 2023

The proposes of this research are to improve the delivery efficiency of AuNPs. One of the problems with drug loading and drug degradation, the drug was loaded onto the surface of the gold particles, adheres to the outer of the surface, which was easy to decompose in the body. In this work, we have developed the coated AuNPs by modified chitosan (Bi-QCS), which the Biotin-Quat188-AuNPs@collagen (Bi-QCS-AuNPS@collagen) was designed as follow: (i) collagen was used as a reducing agent and a stabilizing agent in the AuNPs@collagen, while (ii) modified chitosan (positive charge polymer) was coated on the outer layer, which modified chitosan (Bi-QCS) was consists of a positive charge (Quat188) and a targeting molecule (biotin) to increase cellular uptake and control drug release. After that, 5-Fluorouracil (5-FU) as an anticancer agent was loaded into BiQCS-AuNPs@collagen. The Bi-QCS-AuNPs@collagen was characterized by many techniques. The particle size of AuNPs@collagen increased after coating with Bi-QCS from 30 nm to 50 nm, while the zeta potential change from a negative value (uncoated) to a positive value (coated with Bi-QCS). The coating of Bi-QCS on the surface of AuNPs@collagen can increase the loading efficiency was 87.46 %, while the AuNP@collagen shows a loading efficiency of only 64.67 %. In addition, Bi-QCS-AuNPs@collagen can control the drug release rate, which at pH 5.4 showed the drug release rate higher than pH 7.4 after 48 hours. The evaluation of the biological activity of Bi-QCS-AuNPs@collagen presented significantly higher anti-inflammatory activity and anticancer activity of 5-FU.
Electrocoagulation in two phase separation for manipulation of volatile compound profiles in perfumes
Authors:   , Thaveesangsakulthai Isaya
Published: April 2023

Electrocoagulation (EC) approach employing two aluminium electrodes and a two phase medium of aqueous solution of NaCl and hexane (2-phase-EC) was developed. The approach enabled electrochemical treatment of odor active compounds in perfume extract. The samples before and after 2-phase-EC at cathode, anode and between the two electrodes left for equilibrium after the treatment were analyzed by using solid phase micro extraction (SPME) and gas chromatography hyphenated with mass spectrometry (GC-MS). This allowed identification of volatile compounds in each sample based on comparison with MS and retention index database. After the treatment, the perfume smells were fresher, sweeter and more floral corresponding to their different types and amounts of the odor active compounds. The major odor active products mainly obtained at the anode of the 2-phase-EC system were methyl benzoate, 2-phenylethanol and benzyl acetate. The corresponding product at the cathode was phenylmethanol. Comparison of the investigated sample profiles further reveals enrichment of several compounds at each electrode without undergoing electrochemical reaction. The major reactant and product profiles were further investigated with Gas Analyzer revealing slower rate of decrease in the amounts of the characteristic m/z of the products during the 2-phase EC. The 2-phase-EC and analytical approach have a potential for application in the area of electrochemical reaction in organic media in the future.
Nghiên cứu, thiết kế, chế tạo máy CNC phay mạch in phục vụ công tác đào tạo
Authors: Phương Hoàng Thế
Published: April 2023

Hiện nay, các máy móc thiết bị đều không thể thiếu mạch điện tử bên trong để điều khiển thiết bị hoạt động theo ý muốn. Các sinh viên học ngành kỹ thuật đều được đào tạo về quy trình thiết kế mạch điện tử trên máy tính và chế tạo ra mạch in thực tế. Đối với công đoạn chế tạo mạch sau khi đã có file thiết kế thì hầu hết sinh viên đều sử dụng phương pháp làm thủ công, thực hiện thao tác ăn mòn bằng hóa chất. Điều này dẫn đến mạch sau khi chế tạo không đảm bảo được độ chính xác như file thiết kế vì khi ăn mòn bằng hóa chất có thể dẫn đến trường hợp: ăn mòn không hết, ăn mòn quá nhiều. Điều này sẽ ảnh hưởng đến chất lượng của mạch in sau khi chế tạo, và mạch có thể không hoạt động được ổn định đúng chức năng. Nếu sử dụng máy CNC (Computer Numerical Control) để thực hiện công đoạn phay đường mạch và khoan chân linh kiện thì sẽ đảm bảo được độ chính xác và chất lượng đường mạch được tốt hơn. Nội dung bài nghiên cứu này, tác giả thực hiện việc nghiên cứu, chế tạo máy phay mạch CNC phục vụ công tác đào tạo cho sinh viên trường Đại học Công nghệ Giao thông vận tải.
Aplicação da Lei Rouanet (n. 8.313/91) em projetos de cultura e leitura
Authors: Nascimento Paola Thais Oliveira do , Spudeit Daniela
Published: April 2023

Analisa os projetos voltados à cultura e leitura beneficiados pela Lei Rouanet (Lei nº 8.313/91) no Brasil. Para isso, apresenta-se a Lei Rouanet como uma forma para captar recursos para criar ou melhorar espaços culturais, descreve como a lei pode beneficiar as unidades de informação, apresenta quais as unidades de informação de Santa Catarina foram beneficiadas pela Lei Rouanet, mapeia os tipos de projetos aprovados voltados para cultura e leitura em Santa Catarina via Lei Rouanet entre 2019 e 2021 , e por fim, apresenta os maiores investidores pela Lei na área de Humanidades em Santa Catarina. A pesquisa se caracteriza como natureza aplicada, descritiva e exploratória quanto aos fins, trata-se de uma pesquisa bibliográfica e documental quanto aos meios utilizados, também foi usada as Plataformas Comparar e Versalic do Ministério da Cultura para identificação dos projetos apoiados pela Lei Rouanet em Santa Catarina. Conclui-se que o trabalho proporcionará aos bibliotecários um maior conhecimento sobre a área de políticas públicas, em especial sobre a Lei Rouanet para obter incentivo por meio de empresas tributadas no lucro real como também identificar quem são esses investidores que poderão apoiar o desenvolvimento de projetos na área de cultura e leitura realizada por bibliotecários.
GIẢI PHÁP GẮN PHÁT TRIỂN KINH TẾ - XÃ HỘI VỚI ĐẢM BẢO AN NINH TRẬT TỰ VÙNG ĐỒNG BÀO DÂN TỘC KHMER Ở TÂY NAM BỘ
Authors: Bạch Thanh Sang
Published: April 2023

Đảm bảo an ninh trật tự, góp phần phát triển kinh tế là nhiệm vụ đã và đang được triển khai thực hiện tại các địa phương. Vùng Tây Nam Bộ có những đặc trưng riêng về dân số, dân cư, về tình hình kinh tế - xã hội, an ninh - quốc phòng… Do vậy, việc gắn phát triển kinh tế - xã hội với đảm bảo an ninh trật tự của vùng trong bối cảnh hội nhập quốc tế là vấn đề cần được các cấp chính quyền địa phương quan tâm. Do địa bàn cư trú của đồng bào dân tộc Khmer chủ yếu tập trung ở Tây Nam Bộ; tín ngưỡng của tuyệt đại đa số đồng bào dân tộc Khmer là Phật giáo Nam tông nên khi tiếp cận nghiên cứu về dân tộc Khmer ở Việt Nam cần xét đến cả lịch sử vùng đất Nam Bộ, quan hệ tộc người và tôn giáo. Thông qua phương pháp phân tích, tổng hợp và tổng kết thực tiễn, bài viết đánh giá kết quả thực hiện các chủ trương, chính sách của Đảng, Nhà nước đối với cộng đồng người Khmer; đồng thời đề xuất các giải pháp gắn phát triển kinh tế - xã hội với đảm bảo an ninh trật tự vùng đồng bào dân tộc Khmer ở Tây Nam Bộ, trong tình hình mới.
TIÊU CHUẨN ĐỊNH LƯỢNG CHO MỘT BẢNG ĐIỂM KẾT THÚC HỌC PHẦN ĐẸP
Authors: Trần Doãn Phú , Vũ Công Tuyên
Published: April 2023

Từ khái niệm bài thi đánh giá tương đối (norm referenced test - NRT) và bài thi đánh giá theo chuẩn (criterion referenced test - CRT) (Bond,1996) cùng khái niệm phổ điểm đẹp của một bài thi theo hình thức thi NRT và CRT (Phạm Hiệp, 2015), nghiên cứu đưa ra khái niệm và các tiêu chuẩn định lượng cho một bảng điểm kết thúc học phần đẹp. Điểm mới của nghiên cứu thể hiện ở việc ứng dụng một số kiến thức của Lý thuyết xác suất như hàm mật độ xác suất, xác suất để một biến ngẫu nhiên liên tục nhận giá trị trong một khoảng cho trước, quy tắc 3σ áp dụng cho biến ngẫu nhiên phân phối chuẩn để đưa ra các tiêu chuẩn định lượng cho một bảng điểm kết thúc học phần đẹp theo hình thức thi NRT. Một điểm mới khác của nghiên cứu nằm ở biểu thức giải tích cho hàm mật độ xác suất của phổ điểm đẹp của một bài thi theo hình thức thi CRT. Từ những tiêu chuẩn định lượng cho một bảng điểm kết thúc học phần đẹp, nghiên cứu đưa ra một số đề xuất và khuyến nghị để có một bảng điểm kết thúc học phần đẹp cho bài thi đánh giá tương đối NRT.
TÁC ĐỘNG CỦA CHUYỂN ĐỔI SỐ ĐẾN CÔNG TÁC QUẢN TRỊ NGUỒN NHÂN LỰC TẠI VÙNG ĐÔNG NAM BỘ
Authors: Đỗ Thị Ý Nhi
Published: April 2023

Hiện nay, nền kinh tế kỹ thuật số đã và đang tác động mạnh mẽ đến tốc độ tăng trường của các doanh nghiệp kinh doanh ở nhiều quốc gia thông qua các giao dịch thương mại điện tử cũng như các quy trình sản xuất, quản lý, tương tác với các đối tác, đặc biệt là với khách hàng. Ảnh hưởng của nền kinh tế kỹ thuật số không chỉ giới hạn trong hoạt động kinh doanh thương mại và dịch vụ mà còn mở rộng đến mọi khía cạnh trong cuộc sống. Nghiên cứu này sử dụng phương pháp nghiên cứu định tính, thông qua lược khảo tài liệu làm rõ khái niệm về chuyển đổi số và tác động của nó đến công tác quản trị nguồn nhân lực tại khu vực Đông Nam Bộ. Từ đó xác định chi tiết các điều kiện cần và đủ của công tác quản trị nguồn nhân lực trong thời đại chuyển đổi số. Đồng thời đề xuất các giải pháp phù hợp cho công tác quản trị nguồn nhân lực để thích ứng với quá trình chuyển dịch của nền kinh tế kỹ thuật số tại Đông Nam Bộ.