bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamics of quantum droplets in an external harmonic confinement
Authors: Pathak Maitri R. , Nath Ajay
Published: April 2022

Recent theoretical and experimental results show that one-dimensional (1D) weakly interacting atomic Bose-Bose mixtures with repulsive interspecies mean field (MF) interaction are stabilized by attractive quadratic beyond-mean-field (BMF) effects into self-bound quantum droplet (QD) in free space. Here, we construct an exact analytical model to investigate the structure and dynamics of QDs in presence of external harmonic confinement by solving the 1D extended Gross–Pitäevskii equation (eGPE) with temporal variation of MF and BMF interactions. The model provides the analytical form of wavefunction, phase, MF and BMF nonlinearities. The generation of QDs and interesting droplet to soliton transition in presence of regular/expulsive parabolic traps by taking the comparable MF and BMF interactions are illustrated. We derive the phase diagram of the droplet-soliton phase transition between amplitude of MF, BMF interactions and harmonic oscillator frequency. The strength and form of oscillator frequency are identified as key parameter for tuning the compression, fragmentation and transport of droplets. Finally, the stability of the obtained solutions are confirmed from Vakhitov–Kolokolov (VK) criterion and are found stable.
Sustainable human population density in Western Europe between 560.000 and 360.000 years ago
Authors: Rodríguez Jesús , Willmes Christian , Sommer Christian , Mateos Ana
Published: April 2022

The time period between 560 and 360 ka (MIS14 to MIS11) was critical for the evolution of the Neanderthal lineage and the appearance of Levallois technology in Europe. The shifts in the distribution of the human populations, driven by cyclical climate changes, are generally accepted to have played major roles in both processes. We used a dataset of palaeoclimate maps and a species distribution model to reconstruct the changes in the area of Western Europe with suitable environmental conditions for humans during 11 time intervals of the MIS14 to MIS 11 period. Eventually, the maximum sustainable human population within the suitable area during each time interval was estimated by extrapolating the relationship observed between recent hunter-gatherer population density and net primary productivity and applying it to the past. Contrary to common assumptions, our results showed the three Mediterranean Peninsulas were not the only region suitable for humans during the glacial periods. The estimated total sustainable population of Western Europe from MIS14 to MIS11 oscillated between 13,000 and 25,000 individuals. These results offer a new theoretical scenario to develop models and hypotheses to explain cultural and biological evolution during the Middle Pleistocene in Western Europe.
Effective mathematical modelling of health passes during a pandemic
Authors: Hohenegger Stefan , Cacciapaglia Giacomo , Sannino Francesco
Published: April 2022

We study the impact on the epidemiological dynamics of a class of restrictive measures that are aimed at reducing the number of contacts of individuals who have a higher risk of being infected with a transmittable disease. Such measures are currently either implemented or at least discussed in numerous countries worldwide to ward off a potential new wave of COVID-19. They come in the form of Health Passes (HP), which grant full access to public life only to individuals with a certificate that proves that they have either been fully vaccinated, have recovered from a previous infection or have recently tested negative to SARS-Cov-2. We develop both a compartmental model as well as an epidemic Renormalisation Group approach, which is capable of describing the dynamics over a longer period of time, notably an entire epidemiological wave. Introducing different versions of HPs in this model, we are capable of providing quantitative estimates on the effectiveness of the underlying measures as a function of the fraction of the population that is vaccinated and the vaccination rate. We apply our models to the latest COVID-19 wave in several European countries, notably Germany and Austria, which validate our theoretical findings.
Concordance between biparametric MRI, transperineal targeted plus systematic MRI-ultrasound fusion prostate biopsy, and radical prostatectomy pathology
Authors: Noh Tae Il , Shim Ji Sung , Kang Sung Gu , Cheon Jun , Lee Jeong Gu , Lee Jeong Hyeon , Kang Seok Ho
Published: April 2022

We aimed to confirm the reliability of the results of bi-parametric magnetic resolution imaging-ultrasound fusion targeted and systematic biopsies (bpMRI-US transperineal FTSB) compared to prostatectomy specimens. We retrospectively analyzed the records of 80 men who underwent bpMRI-US transperineal FTSB with region of interest (ROI) and subsequent robot-assisted radical prostatectomy. Changes in the grade group determined by MRI and biopsy versus surgical specimens were analyzed. Thirty-five patients with insignificant prostate cancer and 45 with significant cancer were diagnosed using bpMRI-US transperineal FTSB. Among those with insignificant PCa, 25 (71.4%) were upgraded to significant PCa in prostatectomy specimens: 9/12 (75.0%) with Prostate Imaging Reporting and Data System (PI-RADS) 3, 12/16 (75.0%) with PI-RADS 4, and 4/7 (57.1%) with PI-RADS 5. In the PI-RADS 3 group, the upgraded group showed higher prostate specific antigen (PSA) and PSA density (PSAD) than the concordance group; PSA 8.34(2.73) vs. 5.31(2.46) (p = 0.035) and PSAD 0.29(0.11) vs. 0.18(0.09) (p = 0.025). The results of prostate biopsy and prostatectomy specimens were inconsistent and underestimated in patients with MRI-visible lesions. Therefore, for precise and individualized treatment strategies for PCa with MRI-visible lesions, careful interpretation of biopsy result is required.
Framework for assessing and easing global COVID-19 travel restrictions
Authors: Le Thien-Minh , Raynal Louis , Talbot Octavious , Hambridge Hali , Drovandi Christopher , Mira Antonietta , Mengersen Kerrie , Onnela Jukka-Pekka
Published: April 2022

During the COVID-19 pandemic, many countries implemented international travel restrictions that aimed to contain viral spread while still allowing necessary cross-border travel for social and economic reasons. The relative effectiveness of these approaches for controlling the pandemic has gone largely unstudied. Here we developed a flexible network meta-population model to compare the effectiveness of international travel policies, with a focus on evaluating the benefit of policy coordination. Because country-level epidemiological parameters are unknown, they need to be estimated from data; we accomplished this using approximate Bayesian computation, given the nature of our complex stochastic disease transmission model. Based on simulation and theoretical insights we find that, under our proposed policy, international airline travel may resume up to 58% of the pre-pandemic level with pandemic control comparable to that of a complete shutdown of all airline travel. Our results demonstrate that global coordination is necessary to allow for maximum travel with minimum effect on viral spread.
On-chip-based electrochemical biosensor for the sensitive and label-free detection of Cryptosporidium
Authors: Luka George S. , Najjaran Homayoun , Hoorfar Mina
Published: April 2022

Cryptosporidium, an intestinal protozoan pathogen, is one of the leading causes of death in children and diarrhea in healthy adults. Detection of Cryptosporidium has become a high priority to prevent potential outbreaks. In this paper, a simple, easy to fabricate, and cost-effective on-chip-based electrochemical biosensor has been developed for the sensitive and label-free detection of Cryptosporidium oocysts in water samples. The sensor was fabricated using standard lithography using a mask with a 3-electrode design and modified by self-assembling a hybrid of a thiolated protein/G and the specific anti-Cryptosporidium monoclonal antibodies (IgG3). The electrochemical impedance spectroscopy (EIS) was employed to quantitate C. parvum in the range of 0 to 300 oocysts, with a detection limit of approximately 20 oocysts/5 µL. The high sensitivity and specificity of the developed label-free electrochemical biosensor suggest that this novel platform is a significant step towards the development of fast, real-time, inexpensive and label-free sensing tool for early warning and immediate on-site detection of C. parvum oocysts in water samples, as compared to the traditional methods (such as PCR and microscopy). Furthermore, under optimized conditions, this label-free biosensor can be extended to detect other analytes and biomarkers for environmental and biomedical analyses.
Utilization of the peroxidase-like activity of silver nanoparticles nanozyme on O-phenylenediamine/H2O2 system for fluorescence detection of mercury (II) ions
Authors: Abdel-Lateef Mohamed A.
Published: April 2022

Polyvinylpyrrolidone stabilized silver nanoparticles (PV-AgNPs) were synthesized from AgNO3/trisodium citrate and with the assistance of microwave energy. The synthesized PV-AgNPs were found to own an actual peroxidase mimicking activity. This catalytic activity can oxidize the non-fluorescence reagent (o-phenylenediamine) to a high fluorescence reaction product (2,3-diaminophenazine). The reaction product exhibited a fluorescence emission at 563 nm upon the excitation at 420. Among many metals, only mercury (II) ions can inhibit the catalytic activity of PV-AgNPs nanozyme. Accordingly, the fluorescence intensity of the reaction product has been successfully quenched. This quenching effect in the fluorescence intensity was directly proportional to the concentration of mercury (II). Depending on this finding, a simple, cost-effective, and selective spectrofluorimetric approach has been designed for mercury (II) detection in water samples. The linear relationship between the inhibition in fluorescence intensity and mercury (II) concentration was found in 20–2000 nM with a detection limit of 8.9 nM.
Full factorial design and dynamic modelling of silent and ultrasound-assisted lead and cadmium removal by porous biosorbent
Authors: Ahmed S. Bdaiwi , Dobre T. , Kamar F. Hashim , Mocanu A. , Deleanu I. M.
Published: April 2022

Present work aimed to analyse single and competitive lead and cadmium batch adsorption, using experimental studies and mathematical modelling. The experiments were conducted in silent and ultrasound-assisted systems, in aqueous environment, using grinded hazelnut shells as porous biosorbent. The influence of process factors (pH, adsorbent concentration, adsorbent particle size, and initial species concentration in liquid phase) on species removal efficiency was evaluated when process equilibrium was attained. The statistical study, following a 24 factorial experimental design, allowed the development of a model to predict variables influence. Based on the obtained results a deeper analysis of the separation efficiency, depending on process factors, was conducted. The dynamic study was performed based on experimentally obtained removal rates, modelled considering species diffusion, with reversible kinetics of sorption inside solid particles. Hence, the dynamics of removal efficiency was determined for several representative experiments. The equilibrium isotherms data, best fitted by an appropriate Langmuir model, were used in the dynamic model to reduce the number of model parameters which normally require experimental identification.
Effect of nitrogen and zinc nanofertilizer with the organic farming practices on cereal and oil seed crops
Authors: Kumar Anil , Singh Kapur , Verma Pushpendra , Singh Omkar , Panwar Aashish , Singh Tarunendu , Kumar Yogendra , Raliya Ramesh
Published: April 2022

Sustainable and precision agriculture practices are essential to meet the global food demand with minimal impact on soil, air and water. In the present study, nanofertilizers of nitrogen and zinc was used with the organic farming practice under field condition for the cereal i.e. wheat, pearl millet, and oil seed crops i.e. mustard, sesame. The field trial was compared with chemical fertilizer based agricultural settings. A total of 160 field demonstrations were conducted at two locations: Khaliyawas (28.19° N, 76.76° E) and Khatawali (28.22° N, 76.76° E) of Haryana, India with a total area of 1225 acre and randomized block design. It was found that an average yield was recorded 5.35% higher in wheat, 24.24% higher yield in sesame, 4.2% higher in pearl millet and 8.4% higher yield in mustard by applying nanofertilizers of nitrogen and zinc along with the organic farming practice. The increased yield corroborated with the development parameters of plants such as wheat tillers, ear head length of pearl millet, capsule number per plant in sesame and siliquae number per plant in mustard. The trial observation suggests that the fields with applied organic manure, bio-fertilizer and nanofertilizers in combination resulted in higher yield and better plant growth performances when compared to the fields under conventional chemical fertilizer practice. The results suggest that the intervention of nanotechnology along with organic farming practice can help in minimizing the mass volume requirement of conventional chemical fertilizer while improving crop production.
Laser ablation assisted micropattern screen printed transduction electrodes for sensing applications
Authors: Rehmani Muhammad Asif Ali , Lal Kartikay , Shaukat Ayesha , Arif Khalid Mahmood
Published: April 2022

In this work we present a facile method for the fabrication of several capacitive transduction electrodes for sensing applications. To prepare the electrodes, line widths up to 300 $$\upmu$$μm were produced on polymethyl methacrylate (PMMA) substrate using a common workshop laser engraving machine. The geometries prepared with the laser ablation process were characterised by optical microscopy for consistency and accuracy. Later, the geometries were coated with functional polymer porous cellulose decorated sensing layer for humidity sensing. The resulting sensors were tested at various relative humidity (RH) levels. In general, good sensing response was produced by the sensors with sensitivities ranging from 0.13 to 2.37 pF/%RH. In ambient conditions the response time of 10 s was noticed for all the fabricated sensors. Moreover, experimental results show that the sensitivity of the fabricated sensors depends highly on the geometry and by changing the electrode geometry sensitivity increases up to 5 times can be achieved with the same sensing layer. The simplicity of the fabrication process and higher sensitivity resulting from the electrode designs is expected to enable the application of the proposed electrodes not only in air quality sensors but also in many other areas such as touch or tactile sensors.
The importance of pH adjustment for preventing fibrin glue dissolution in the stomach: an in vitro study
Authors: Takegawa Yoshitaka , Takao Toshitatsu , Sakaguchi Hiroya , Nakai Tatsuya , Takeo Kazuhiro , Morita Yoshinori , Toyonaga Takashi , Kodama Yuzo
Published: April 2022

Combined use of fibrin glue and polyglycolic acid (PGA) sheets has attracted attention as a preventive measure for complications associated with endoscopic submucosal dissection. However, fibrin glue is a protein that may be dissolved by gastric acid. We evaluated the effect of artificial gastric acid on fibrin clot. The dissolution time of three layers of fibrin glue with PGA sheets was measured in five groups (pH 1.2, 2.0, 4.0, 5.5, and 6.0 with pepsin). Measurements of three samples per group were made. The mean number of the remaining layers at each measurement point was observed for 168 h. The time to complete dissolution of the three layers of fibrin gel in the three samples was 2.5 h at pH 1.2, 5 h at pH 2.0, 24 h at pH 4.0, and 48 h and 6 h at pH 5.5. In order to maintain fibrin glue in the stomach for a long period, there was a need to avoid pepsin activation secondary to acidification of gastric juice. The use of strong antacids is recommended.
Assessment of acute toxicity and developmental transformation impacts of polyethylene microbead exposure on larval daggerblade grass shrimp (Palaemon pugio)
Authors: Gray Austin D. , Weinstein John E. , Riegerix Rachelle C.
Published: April 2022

Due to the ubiquity of microplastic contamination in coastal waters, there is potential for adverse impacts to organism development. One organism of interest is the daggerblade grass shrimp,Palaemon pugio, an ecologically important species in estuaries along the east coast of North America. We exposed larval grass shrimp to virgin polyethylene microbeads (35 and 58 µm) at a high (0.375 and 1.95 mg/L), medium (0.0375 and 0.195 mg/L), and a low concentration (0.00375 and 0.0195 mg/L), respectively for 23 days to assess mortality, transformation time from larval to juvenile stage, and weight. Average percent mortality was 3.7 to 4.8 times higher in the experimental treatments compared to controls. The greatest proportion of mortality was observed in the first 11 days. Median time for transformation ranged from 20.2 to 20.8 days. Shrimp exposed to the 35 µm beads in the high treatment (20.2 days) transformed significantly faster than the control shrimp (20.8 days). Although development was not delayed and size of the shrimp did not differ, the acute toxicity of microplastics on grass shrimp is a concern due to their role in energy cycling within tidal-creeks. These findings suggest potential population and community level effects following microplastic exposure.
Artificial intelligence significantly improves the diagnostic accuracy of deep myxoid soft tissue lesions in histology
Authors: Yeung Maximus C. F. , Cheng Ivy S. Y.
Published: April 2022

Deep myxoid soft tissue lesions have posed a diagnostic challenge for pathologists due to significant histological overlap and regional heterogeneity, especially when dealing with small biopsies which have profoundly low accuracy. However, accurate diagnosis is important owing to difference in biological behaviors and response to adjuvant therapy, that will guide the extent of surgery and the need for neo-adjuvant therapy. Herein, we trained two convolutional neural network models based on a total of 149,130 images representing diagnoses of extra skeletal myxoid chondrosarcoma, intramuscular myxoma, low-grade fibromyxoid sarcoma, myxofibrosarcoma and myxoid liposarcoma. Both AI models outperformed all the pathologists, with a significant improvement of accuracy up to 97% compared to average pathologists of 69.7% (p < 0.00001), corresponding to 90% reduction in error rate. The area under curve of the best AI model was on average 0.9976. It could assist pathologists in clinical practice for accurate diagnosis of deep soft tissue myxoid lesions, and guide clinicians for precise and optimal treatment for patients.
The rising moon promotes mate finding in moths
Authors: Storms Mona , Jakhar Aryan , Mitesser Oliver , Jechow Andreas , Hölker Franz , Degen Tobias , Hovestadt Thomas , Degen Jacqueline
Published: April 2022

To counteract insect decline, it is essential to understand the underlying causes, especially for key pollinators such as nocturnal moths whose ability to orientate can easily be influenced by ambient light conditions. These comprise natural light sources as well as artificial light, but their specific relevance for moth orientation is still unknown. We investigated the influence of moonlight on the reproductive behavior of privet hawkmoths (Sphinx ligustri) at a relatively dark site where the Milky Way was visible while the horizon was illuminated by distant light sources and skyglow. We show that male moths use the moon for orientation and reach females significantly faster with increasing moon elevation. Furthermore, the choice of flight direction depended on the cardinal position of the moon but not on the illumination of the horizon caused by artificial light, indicating that the moon plays a key role in the orientation of male moths.
Drug-resistant focal epilepsy in children is associated with increased modal controllability of the whole brain and epileptogenic regions
Authors: Chari Aswin , Seunarine Kiran K. , He Xiaosong , Tisdall Martin M. , Clark Christopher A. , Bassett Dani S. , Scott Rod C. , Rosch Richard E.
Published: April 2022

Network control theory provides a framework by which neurophysiological dynamics of the brain can be modelled as a function of the structural connectome constructed from diffusion MRI. Average controllability describes the ability of a region to drive the brain to easy-to-reach neurophysiological states whilst modal controllability describes the ability of a region to drive the brain to difficult-to-reach states. In this study, we identify increases in mean average and modal controllability in children with drug-resistant epilepsy compared to healthy controls. Using simulations, we purport that these changes may be a result of increased thalamocortical connectivity. At the node level, we demonstrate decreased modal controllability in the thalamus and posterior cingulate regions. In those undergoing resective surgery, we also demonstrate increased modal controllability of the resected parcels, a finding specific to patients who were rendered seizure free following surgery. Changes in controllability are a manifestation of brain network dysfunction in epilepsy and may be a useful construct to understand the pathophysiology of this archetypical network disease. Understanding the mechanisms underlying these controllability changes may also facilitate the design of network-focussed interventions that seek to normalise network structure and function.
Screening and identification of key microRNAs and regulatory pathways associated with the renal fibrosis process
Authors: Li Xiang , Dong Zhi-Qiang , Chang Hong , Zhou Hong-Bing , Wang Jia , Yang Zhan-Jun , Qiu Min , Bai Wan-Fu , Shi Song-Li
Published: April 2022

This study analyzed the miRNA network involved in the occurrence and development of renal fibrosis in rats using transcriptomics and bioinformatics to identify novel diagnostic biomarkers and potential therapeutic targets.
Correction: Fast label-free recognition of NRBCs by deep-learning visual object detection and single-cell Raman spectroscopy
Authors: Fang Teng , Yuan Pengbo , Gong Chen , Jiang Yueping , Yu Yuezhou , Shang Wenhao , Tian Chan , Ye Anpei
Published: April 2022

Correction for ‘Fast label-free recognition of NRBCs by deep-learning visual object detection and single-cell Raman spectroscopy’ by Teng Fang et al., Analyst, 2022, https://doi.org/10.1039/D2AN00024E
Cerium versus zirconium UiO66 metal–organic frameworks coupled with CdS for H2 evolution under visible light
Authors: Hou Wenqing , Chen Chen , Wang Yaru , Xu Yiming
Published: April 2022

Metal–organic frameworks (MOFs) as highly porous photocatalysts have received increasing attention.
Slow magnetic relaxation in dinuclear Co(iii)–Co(ii) complexes containing a five-coordinated Co(ii) centre with easy-axis anisotropy
Authors: Liu Mengyao , Yang Yimou , Jing Rong , Zheng Shaojun , Yuan Aihua , Wang Zhenxing , Luo Shu-Chang , Liu Xiangyu , Cui Hui-Hui , Ouyang Zhong-Wen , Chen Lei
Published: April 2022

Synthesis, structure, magnetic anisotropy and slow magnetic relaxation of two air-stable Co(iii)–Co(ii) mixed-valence complexes with a five-coordinated Co(ii) centre were studied by single-crystal X-ray crystallography, magnetometry and HFEPR.
Electrocatalytic CO2 reduction reaction on dual-metal- and nitrogen-doped graphene: coordination environment effect of active sites
Authors: He Peinan , Feng Haisong , Wang Si , Ding Hu , Liang Yujie , Ling Min , Zhang Xin
Published: April 2022

As the coordination number of metal and nitrogen increases from 2 to 4, the stability, activity and selectivity of bimetallic catalysts, and the synergistic effect between heteronuclear bimetals, are significantly improved.
Correction: Duetting electronic structure modulation of Ru atoms in RuSe2@NC enables more moderate H* adsorption and water dissociation for hydrogen evolution reaction
Authors: Chen Ding , Lu Ruihu , Yao Youtao , Wu Dulan , Zhao Hongyu , Yu Ruohan , Pu Zonghua , Wang Pengyan , Zhu Jiawei , Yu Jun , Ji Pengxia , Kou Zongkui , Tang Haolin , Mu Shichun
Published: April 2022

Correction for ‘Duetting electronic structure modulation of Ru atoms in RuSe2@NC enables more moderate H* adsorption and water dissociation for hydrogen evolution reaction’ by Ding Chen et al., J. Mater. Chem. A, 2022, 10, 7637–7644, https://doi.org/10.1039/d2ta01032a.
AIE-active organic resonance molecules for highly sensitive dynamic explosive detection
Authors: Jiang He , Zhang Longyan , Xian Lijie , Wang Zijie , Jin Jibiao , Zheng Chao , Chen Runfeng
Published: April 2022

AIE-active resonance molecules designed by rational integration of AIE and resonance units show enhanced emission for dynamic self-adaptive high-performance explosive detection.
Finite element analysis of tibio‐femoral contact mechanics of a customised knee spacer
Authors: Choh Alex C. T. , Yew Andy , Yeo Seng Jin , Chong Desmond Y. R. , Chia Shi‐Lu
Published: April 2022

With one‐third of patients having osteoarthritis predominantly in one compartment of the knee, unicompartmental knee spacers have been introduced as a less invasive alternative to total knee replacement. However, patients with the knee spacer implanted were seen to have persistent pain, resulting in high revision rates. A static finite element model of the knee and its interaction with a knee spacer implant at full extension and 90° flexion was used to investigate the tibio‐femoral contact mechanics of the knee joint after a knee spacer surgery. Three different knee spacer designs (contoured, flat and C‐shaped) were modelled and prescribed with cobalt‐chrome, ultra‐high molecular polyethylene and polyurethane material properties. The results suggested that a softer spacer is generally preferred as this helps in the conformity of knee spacer to the condyle, effectively distributing the load subjected to the implant. Flat spacers that result in high stresses resulting from lower contact areas should be avoided.
Efficient modelling of natural gas pipeline on electromagnetic transient simulation programs
Authors: Song Ruikai , Xia Yue , Chen Ying , Du Songhuai , Strunz Kai , Song Yankan , Fang Wang
Published: April 2022

Electromagnetic transient programs (EMTPs) are widely used for simulating electromagnetic transient in power systems. With the increasing interest in integrated energy system (IES), it would be beneficial to extend the scope of EMTP‐type application to multi‐physics transients in integrated electrical and gas networks. An efficient and accurate model of gas pipeline is proposed in EMTP for the simulation of pneumatic transients. The pipeline is split into a number of segments using spatial discretization. Analogies between pneumatic and electric quantities, such as flow and pressure, current, and voltage, are used to create a circuit representation of pipe segment. The pipeline is represented by a distributed‐element model. In order to enhance the computational efficiency, the nodal equation for pipeline model is reformulated. The pipeline model appears as a two‐port Norton equivalent with constant admittances. Case studies are performed to demonstrate the accuracy and efficiency of the proposed pipeline model. The implementation of the proposed pipeline model in the EMTP‐type program power systems computer aided design (PSCAD) enables the analysis of diverse transients in integrated electrical and gas systems (IEGSs).
Treatment of Suspect Feline Panleukopenia in Cat at Healthy Pet Animal Clinic in Madiun
Authors: Endah Anggraeni Henny , Nurhudayanto Muhammad , Aprillia Mutiara Fitri Winantika
Published: April 2022

Feline panleukopenia is a highly contagious, often fatal, viral disease of cats. This scientific report aims to describe information about treatment of suspect feline panleukopenia in cat at Healthy Pet in Madiun East Java, Indonesia. Daily observations on a cat (Moni) hospitalized for dehydration, vomiting and diarrhoea, WBC count 1,400 cell/mm3. The treatment had 3 components of monitoring, medication, and biosecurity application. Monitoring was 4 times a day (temperature, faeces consistency, vomiting and appetite) for 8 days. Medication was antibiotics Sulfadiazine® to treat secondary bacterial infections, Ondansetron® to control of vomiting and Loperamid® to control of diarrhoea. Fluid therapy RL was performed to correct dehydration and electrolyte abnormalities. Biosecurity application was applied as breaking the chain of transmission (isolation room, sanitation 2 times a day and physical distancing). The cat was declared healthy on 8th day based on WBC count 15,900 cell/mm3, good appetite and normal defecation.
Noise Variation Between Days and Hours in an Urban Areas
Authors: Paramitadevi Yudith Vega , Basalamah Shakilah Faradiba , Viani Okta , Prigel Milgamas Ratna
Published: April 2022

Noise disturbance quality standards which refer to Indonesian Government Decree number 22 of 2021 concerning Environmental Management in the future will be drawn up. This possibility has prompted several local governments to measure and map noise in their respective areas. The commonly used pattern in noise studies is taking grab samples and processing the test sample data using extrapolation techniques in order to obtain long-term noise levels. The approach requires a sufficient literature base. This study analyzed noise based on daily data at three different locations in the City of Jakarta, Indonesia. The three locations were construction site, industrial area and along inner-city toll road. Analysis of ANOVA variance at daily and hourly levels for 42 LA eq was presented in this study. Statistical results showed significant differences between hourly and daily periods, so further attention is needed on the extrapolation approach that represents long-term noise levels. The longer the noise analysis period in an area, the more accurate the characterization of noise in the study area will be.
Quality of Garlic Bulbs with Irrigation Application according to Plant Needs
Authors: Cartika Ika , Rahayu Suwarni Tri , Basuki Rofik Sinung , Musaddad Darkam
Published: April 2022

The irrigation technique that has been done by farmers so far has not been optimal in increasing garlic production. This study aims to evaluate the quality of garlic tubers with irrigation applications according to plant needs. The experiment was carried out in Lembang, West Java, in 2020. The method used in this study was a group design of 6 treatments with four replications. Treatment A (daily ET accumulation within two days), B (daily ET accumulation within three days), C (daily ET accumulation within four days), D (daily ET accumulation within five days), E (daily ET accumulation within six days), F (farmers' irrigation practices). The plant data obtained were analyzed using Analysis of Variance (ANOVA) at the 5% level. Data analysis was performed using the PKBT - STAT 1.01 program. The results showed that the tuber diameter in treatment B (daily ET accumulation within three days) was significantly greater than control. Weight, weight loss, and water content were not significantly different between all treatments. The volatile content in all treatments was significantly higher than control.
Vertical farming application with several growing media for coffee nurseries
Authors: Puji Mumpuni Restu , Fatchur Rochmah Hidayati , Undang
Published: April 2022

Coffee is one of the plantation commodities that play an important role as a source of foreign exchange for the country. One alternative to overcome the land decrease in rural area is to utilize urban farming in the form of a vertical planting system. This study aimed to obtain alternative techniques for planting coffee seedlings using vertical farming and to determine the effect of vertical planting with several growing media on the growth of coffee seedlings. The study was arranged in a non-factorial Randomized Block Design (RBD) with four treatments, namely: 1) conventional nursery; 2) topsoil verticulture nursery; 3) topsoil and compost media verticulture, and 4) topsoil, compost, and husk charcoal media verticulture. The data were analyzed using the Duncan Multiple Range Test (DMRT). The observed variables included observations of the morphology of coffee seedlings and verticulture environmental factors. The results showed that vertical planting on the vegetative growth of coffee seedlings was not significantly different from conventional planting. Topsoil planting media and husk charcoal in vertical planting did not significantly affect the morphological growth of coffee seedlings. The combination of topsoil, husk charcoal and compost gave the best plant height of 12.4 cm at 13 weeks after planting.
Milk Quality Improvement with AHP (Analytical Hierarchy Process) Based on SCOR (Supply Chain Operation References) Performance and Business Canvas Model in Giri Tani Milk Cooperative
Authors: Nurdialy Mela , Irawan Suhendi , Tutur Risyahadi dan Sazli
Published: April 2022

KUD Giri Tani has faced varying quality of milk, resulting in several times rejection of milk by the industry. The programs that have been running are unable to provide the same quality milk. This research aims to prioritize programs that will be implemented by the top management of KUD Giri Tani. This research uses SCOR reference and Business Canvas Model to investigate proper improvement methods. The weighting level 1 shows that the top 3 significantly affect milk quality such as production, milk supply from farmers, and delivery. The weighting calculation for core activity shows that Plan Reliability (0.0439), Source Reliability (0.0825), Makes Effectivity (0.1513), Delivery Reliability (0.1160), and Return Reliability (0.0513) are the most significant weights of each criterion. The result shows that improving food quality is the highest score (0.393) followed by improvement hygiene (0.386) and milk grading process (0.221). The Farmer members can focus on those two things to improve the quality of milk produced. Those programs are appropriate to analyze the Business Canvas Model.
Determination of LC50 and Clinical Symptoms of Aeromonas hydrophila Infection on the Fingerlings of Semah (Tor soro), the Indonesian Native Freshwater Fish
Authors: Amalia Putri Firdausi ,   Rahman, Muhammad Arif Mulya
Published: April 2022

Aeromonas hydrophila is a bacterial pathogen in freshwater aquaculture causing the motile aeromonad septicemia (MAS) disease and inflict significant economic losses. This study aimed to determine the lethal concentration (LC50-48h) of A. hydrophila on Tor soro's fingerlings and investigated the clinical signs that appeared following the challenge test. Briefly, 150 fingerlings (3,4 ± 0,18 cm) were challenged by immersion means with 0 (control), 104, 105, 106 and 107 CFU/mL of live cells of A. hydrophila. Reed and Muench’s method’s determination of LC50-48h was calculated and all clinical signs that appeared during the test were recorded. The result showed that the LC50-48h by immersion was 1.0 x 106,66 CFU/mL with clinical signs observed as hemorrhages, depigmentation, lesions, anorexia, loss of balance, and enlargement of the abdominal cavity. Furthermore, based on the LC50-48h and the clinical symptoms, this study reveals that even though all symptoms are consistent among the fish, the severity of the disease tends to be prevalent and intense as the concentration of pathogen is higher.
How can blended learning contribute to the development of dairy professionals within the global dairy sector?
Authors: van der Horst Nicolien
Published: April 2022

This research focuses on the goal to determine the effect of blended learning in the global dairy sector and to what extent this method has an added value. It was carried out by a 4th-year thesis student from the Animal Husbandry study at the Van Hall Larenstein University in the Netherlands. This research is substantiated by information gathered while participating in creating blended learning modules with Triple Dairy, through literature research, interviews with ten stakeholders in the transfer of knowledge, and two different surveys with Dutch farmers and African trainers of the EARNED project. The research goal is to determine how blended learning is most effective in the global dairy sector and what added value this method has. This research aims to deliver a report, article, and consultation that clarifies how blended learning can contribute to the development of dairy professionals in the global dairy sector.
Correlation between teat length and lactation periods on the level of subclinical mastitis occurrence in Sappy Valley Farm
Authors: Siagian Tetty Barunawati , Amidjaya Surya Hapsara
Published: April 2022

This study aims to determine the correlation between dairy cattle teat length at several lactation periods and subclinical mastitis profile. This study used 43 dairy cattle at several lactation periods. The lactation periods of the cows studied were lactation periods 1, 2, and 3. Subclinical mastitis testing used IPB-1 Mastitis Test, and teat length was measured using a measuring tape (cm). The data is taken and then analyzed using the average and described. The results showed that the average teat length of 5.11 cm did not experience subclinical mastitis, while the average teat length was 5.48 cm, 6.09 cm, and 7.28 cm, respectively, had subclinical mastitis. The highest incidence of subclinical mastitis is influenced by teat length and lactation period. The length of the teat and the lactation period, the higher the severity of subclinical mastitis. These findings are essential for a practical clinical diagnostic approach in dairy cattle with subclinical mastitis.
Load Balancing Simulation Android Application as an Online Learning Media
Authors: Sholihah Walidatush , Abdul Malik Ahmad , Novianty Inna , Aziezah Nur
Published: April 2022

Learning activities during the covid pandemic are carried out online. Learning materials are delivered synchronously or asynchronously. Asynchronous techniques allow students to learn independently, and materials can be studied repeatedly. One way that can be used to convey material is through simulation. The students will understand the learning material better using simulation. The simulation made in this paper is a load balancing material simulation. This material is studied by students in computer network studies at both high school and college. Load balancing is a technique for dividing the load on the server. The algorithms discussed in this simulation are round-robin and least connected. In this simulation, the user is invited to interact with the application and see the difference between the two algorithms. The method used to create the application consists of five stages. The stages are problem analysis, application design, development, and testing. This simulation application is made using GameMakerStudio 14.9 and can be installed on Android devices. The application was tested on 20 users with vocational education backgrounds and students. More than 50% of users say this application is easy to use and the material is easy to understand.
Artificial Coral Reef Growth Media Model Engineering from Ceramic
Authors: Muliawati Ni Putu , Setiadi I Made Dwi , Verma Guino , Donna Wardani Maya Larasati , Otivriyanti Geby
Published: April 2022

The experiment on the artificial coral reef was conducted at BTIKK using ceramic body mass code BL1. This engineering was carried out in two steps, the first step was making the design of the growth media, and the second step was testing the mass of the ceramic body and making the growth media model. The hexagonal design was used beginning from the design concept that applies geometric shapes with many sides, making it easier to arrange the formation under the sea. Aesthetically, the hexagonal shape can represent a design concept. It resulted from integration in the design of coral reef planting media with natural marine ecosystems and can produce new experiences and impressions to attract people's attention to pay more attention to the preservation of coral reefs. The assessment of fired shrinkage, water absorption, and apparent porosity on body mass for making the growth medium model was tested on 15 test pieces. The average value of fired shrinkage on 900°C temperature fired test pieces is 1.3%, the average water absorption is 19.7%, and the apparent porosity is 32.9%. Their value could be used to make artificial coral reef growth media.
Fractals, metamorphoses and symmetries in quantum field theory
Authors: Vitiello Giuseppe
Published: April 2022

The mechanism of spontaneous breakdown of symmetry in quantum field theory is reviewed, the Goldstone theorem derived and the formation of ordered patterns is discussed. Metamorphoses and fractal self-similarity are described in terms of the dynamical rearrangement of symmetry in spontaneously broken symmetry theories. The isomorphism between fractal self-similarity and deformed coherent states is exhibited. It is also discussed how the missing of infrared terms in physical observations is responsible of the metamorphosis processes. The dynamical generation of squeezed, entangled coherent states plays a crucial role in the formation of ordered patterns (morphogenesis). The discussion on metamorphoses and other results extend to condensed matter physics, elementary particles, biological systems and brain studies.
Lexical Neighborhood Test: Test-Retest Reliability and Interlist Equivalency
Authors: Kirk Karen Iler , Eisenberg Laurie S. , Martinez Amy S. , Hay-McCutcheon Marcia
Published: April 2022

This study examined the reliability and interlist equivalency of two new recorded spoken word recognition measures, the Lexical Neighborhood Test (LNT) and the Multisyllabic Lexical Neighborhood Test (MLNT), and evaluated the effects of lexical difficulty on spoken word recognition by children with hearing loss. Participants were 16 children with prelingual, profound deafness who used a cochlear implant. Test-retest reliability was high and no significant interlist differences were observed for both measures. In addition, we found that lexically "easy" words (i.e., those that occur often and have few phonemically words with which they are similar) were recognized correctly more often than lexically "hard" words (i.e., those with opposite characteristics). The results demonstrate that the LNT and MLNT provide reliable information about the spoken word recognition abilities of children with profound hearing loss who use cochlear implants. In addition, these new measures also provide more detailed information about the way in which these children organize and access spoken words from long-term lexical memory.

Abbreviations: CHILDES = Child Language Data Exchange System; LNT = Lexical Neighborhood Test; MLNT = Multisyllabic Lexical Neighborhood Test; NAM = Neighborhood Activation Model; OC = oral communication; PB-K = Phonetically Balanced Kindergarten Word Lists; PTA = average of the pure-tone threshold hearing levels at 500, 1000, and 2000 Hz; SPL = speech presentation level; TC = total communication
Hit and False-Positive Rates for the Middle Latency Response in Patients with Central Nervous System Involvement
Authors: Musiek Frank , Charette Lori , Kelly Tim , Lee Wei Wei , Musiek Erik
Published: April 2022

We sought to determine the test efficiency of the middle latency evoked response for identifying or differentiating subjects with and without central nervous system (CNS) involvement. Receiver operating characteristic curves were established for hit and false-positive rates for 26 subjects with CNS lesions and 26 control subjects matched for age and hearing sensitivity. The lesions involved but were not limited to the auditory regions of the CNS. Middle latency evoked response latency and amplitude measurements were made for the Na and Pa waves recorded at C3 and C4 electrode sites following stimulation of the left and right ears. Intrasubject comparisons were made for ipsilateral and contralateral stimulation/recording conditions. Amplitude measures were superior to latency measures. For amplitude, percentage differences from contralateral comparisons proved to be the most sensitive and specific measure. The clinical implications of findings are discussed.

Abbreviations: ABR = auditory brainstem response, CANS = central auditory nervous systems, CNS = central nervous system, MLR = middle latency response, ROC = receiver operating characteristics
Digital Versus Analog Signal Processing: Effect of Directional Microphone
Authors: Valente Michael , Sweetow Robert , Potts Lisa G. , Bingea Becky
Published: April 2022

Differences in performance were evaluated between the Widex Senso C8 (omnidirectional) and C9 (directional) hearing aids and analog hearing aids currently worn by 40 subjects with hearing loss. Subjects were fit with the C8 and C9 using the manufacturer's recommended procedure. Differences in performance between the C8 and C9 and the subjects' own hearing aids were assessed using the Speech Perception in Noise (SPIN) test administered at +7, 0, and -7 dB signal-to-noise ratio (SNR) with the noise fixed at 65 and 75 dB SPL. Also, a questionnaire was completed assessing differences in preference between the C9 and the subjects' own hearing aids. The major finding was the presence of a significant advantage of the C9 relative to the C8 and the subjects' own hearing aids at each experimental condition. The magnitude of the advantage provided by the C9 increased as the SNR became more difficult. However, significant differences were not present between the C8 and the subjects' own hearing aids at any experimental condition. The questionnaire revealed a statistically significant preference for the C9 in comparison to the subjects' own hearing aids.

Abbreviations: ANSI = American National Standards Institute, BTE = behind the ear, CIC = completely in the canal, DSP = digital signal processing, FBR = front-to-back ratio, HP = high predictability, ITE = in the ear, LP = low predictability, PI = performance intensity, SNR = signal-to-noise ratio, SPIN = Speech Perception in Noise
Intrasubject Test-Retest Reliability in Tympanic Electrocochleography
Authors: Park Debra L. , Ferraro John A.
Published: April 2022

To help establish the clinical reliability of electrocochleography (ECochG), we defined normal limits of variability for the summating potential (SP)/auditory nerve action potential (AP) amplitude ratio across multiple recording sessions from the same subjects. ECochG was recorded bilaterally from the tympanic membranes of 10 normal-hearing adults at six sessions separated by 2– to 14–day intervals. The measures of variability examined included overall range, overall average standard deviation, and mean average difference. Examiner improvement over the six sessions also was examined. Results from the variability data indicate that the reliability of tympanic ECochG can be determined by how many of the measures of variability fall within the normal limits established in this study. No significant examiner improvement was seen between the first three and last three recording sessions.

Abbreviations: ABR = auditory brainstem response, AP = action potential, dB SL = decibels referenced to sensation level, ECochG = electrocochleography, ECochGm = electrocochleogram, MD/ELH = Meniere's disease/endolymphatic hydrops, N1 = first peak of the AP, SP = summating potential, TM = tympanic membrane
Sertraline Hydrochloride Withdrawal-Induced Unilateral Tinnitus: Case Study
Authors: Navarro Richard
Published: April 2022

Sertraline hydrochloride (Zoloft—Roeris Division, Pfizer Incorporated, New York) is an antidepressant medication that has numerous side effects, including dizziness, nausea, and tinnitus, documented during the period of medication. This presentation reports on Zoloft-induced unilateral tinnitus that resulted from withdrawal of the medication in a male patient with bilateral hereditary sensory hearing loss and concomitant clinical depression.