bluuebunny/crossref_metadata_2025 huggingface dataset:
Tecnologias da informação e comunicação no ensino da Fisioterapia, Terapia Ocupacional e Fonoaudiologia durante a pandemia de COVID-19
Authors: Galvão Maria Cristiane Barbosa , Ricarte Ivan Luiz Marques , Rezende Gabriela , Calandrin Isabela Dallasta
Published: September 2023

Resumo Preocupações relacionadas ao uso de tecnologias no ensino superior são recorrentes em vários países e áreas do conhecimento. Este estudo transversal exploratório mapeou usos e percepções sobre as tecnologias da informação e comunicação no ensino de Fisioterapia, Terapia Ocupacional e Fonoaudiologia durante a pandemia de COVID-19, no Brasil, por meio de um questionário online. Participaram do estudo 87 acadêmicos vinculados a cursos de Fonoaudiologia, Fisioterapia e Terapia Ocupacional. No que concerne ao apoio institucional recebido durante a pandemia para o uso de tecnologias de informação e comunicação no processo de ensino-aprendizagem, 84 participantes se manifestaram, dos quais 13 (15,5%) declararam que este apoio foi ruim; 40 (47,6%) que o apoio foi regular, 23 (27,4%) que o apoio foi bom e 8 (9,5%) que o apoio foi ótimo. A análise temática de 87 respostas observou a predominância de três temas: percepções positivas sobre o uso de tecnologias, percepções relacionadas às adversidades no uso de tecnologias e percepções relacionadas às estratégias para aperfeiçoar o uso das tecnologias de informação e comunicação no processo de ensino-aprendizagem, havendo destaque para as percepções sobre adversidades. Notou-se que o ensino remoto possui desvantagens derivadas do potencial despreparo da comunidade acadêmica para o uso de tecnologias, bem como especificidades relacionadas ao campo da saúde como a necessária relação aluno-paciente. Assim, os usos de tecnologias da informação e comunicação no ensino destas áreas demandam atenção aprofundada das instituições de ensino superior e comunidade acadêmica para a adoção, treinamento e avaliação de inovações.
Multiskilled labor force: a discussion of this missing link of lean construction in Brazilian companies
Authors: Abreu João Paulo Maciel de , Cardoso Gabriel de Camargo , Marchiori Fernanda Fernandes , Brandstetter Maria Carolina Gomes de Oliveira , Heineck Luiz Fernando Mählmann
Published: September 2023

Abstract Multiskilled labor is a ubiquitous concept and its adoption is suggested in various production approaches such as sociotechnical systems, cellular arrangements and, most notably, related to Lean Production, as it provides flexibility to the work environment. This research work aimed at identifying the extent of the use of multiskilling in a sample of Brazilian construction sites. A survey was conducted comprising variables such as reasons for simultaneous use of specialized and multiskilled labor. A total of 191 valid questionnaires were returned. Statistical analyses point out that it is common to employ both specialized and multiskilled labor in the majority of sites. Furthermore, multiskilling and subcontracting are concomitant flexible strategies to accommodate labor provision on site. The share of multiskilling is greater than reported in academic works, the number of skills is as restricted as in literature propositions and the size of the building firm is determinant of the share of multiskilled labor in the total workforce. This research work concludes that: work flexibility may be obtained with different strategies (multiskilled; specialized and multiskilled; subcontracting); employing only specialized trades is not a dominant culture on building sites.
Probabilistic model for urban traffic noise analyses using real sound signals
Authors: Guedes Italo César Montalvão , Bertoli Stelamaris Rolla , Montalvão Jugurta
Published: September 2023

Abstract Vehicular traffic is pointed out as a major source of urban noise pollution today. In this paper, we evaluated the precision of a new probabilistic model for urban traffic noise analyses. The proposed model adopts real sound signals and the Monte Carlo method in simulations. Probability distributions of traffic variables were obtained in-situ on two urban roads. The acoustic signals and corresponding energies of single pass-by of vehicles were obtained usingsound signal recordings on test tracks under free-field condition. The model simulates vehicular traffic noise on urban roads in free or in trafficlight controlled flow and considers the influence of bus stops.The proposed model calculates different acoustic descriptors, such as Statistical sound levels (LA10 and LA90), Equivalent continuous sound level (LAeq), Trafficnoise index (TNI) and Noise pollution level (LNP). Furthermore, it allowsthe listening of simulated noise. The experimental results indicate that theproposed model is reliable and accurate for vehicular traffic noise prediction.
Influência dos compósitos na isolação sonora de vedações em bloco de gesso
Authors: Silva Júnior Otávio Joaquim da , Oliveira Tiago Ancelmo de Carvalho Pires de , Silva José Jeferson do Rego
Published: September 2023

Resumo As propriedades internas dos materiais, como densidade, rigidez e amortecimento, influenciam diretamente na capacidade de isolação sonora de vedações verticais ao ruído aéreo, e aumentar a isolação sonora requer conhecimento dessas propriedades. Entre os materiais utilizados na construção civil brasileira destaca-se o bloco de gesso, pois possui dimensões que aumentam sua produtividade e menor densidade que os blocos cerâmico e de concreto. Contudo, sua capacidade de isolação sonora não é diferente dos sistemas construtivos convencionais. Diante da necessidade de aumentar a capacidade de isolação sonora das vedações em bloco de gesso, esta pesquisa analisou o índice de isolação sonora de paredes executadas com blocos de gesso, espessura de 50 mm e relação água/gesso de 1.0, e paredes executadas com blocos de gesso compósitos de perlita natural, perlita expandida, vermiculita e alumina. A isolação sonora dos blocos compósitos de perlita natural e perlita expandida proporcionaram aumento na isolação sonora de 3 dB e 4 dB, respectivamente. Já os blocos compósitos de vermiculita e alumina apresentaram a maior eficiência, promovendo ganhos de 7 dB, em relação ao bloco de gesso padrão, com apenas 5% de adição. Os resultados apresentados neste trabalho contribuem para produção de blocos de gesso com maior eficiência acústica, fornecendo ao mercado alternativas para garantir o isolamento acústico necessário.
COUPLED EFFECT OF SOLID FRACTION AND INTERNAL ENERGY SOURCE ON CONVECTIVE HEAT TRANSPORT IN THREE-LAYERED AIR-POROUS-AIR DOMAIN: COMPARISON WITH DIFFERENT TWO-LAYERED DOMAINS
Authors: Kolchanova Ekaterina A. , Sagitov Rafil V.
Published: September 2023

This paper studies convective heat transport driven by a uniform internal energy source coupled with the solid fraction in the partial air-saturated porous domains bounded by the top and bottom impermeable thermally conductive surfaces. The consideration of the coupled effect distinguishes our work from the papers of previous authors. We provide a comprehensive numerical study of internal convection and compare results of the linear stability analysis for three distinct domains. The first domain is air-porous-air (APA), where the heat-generating porous matrix is between the upper and lower air layers. In the second air-porous (AP) domain, the air layer overlays the porous medium. In the third porous-air (PA) domain, the air layer underlays the porous medium. The bimodal marginal stability curves and regime map with a demarcation line between the local and large-scale convective flows are obtained only for the APA and AP domains due to the division of each domain into the upper unstably stratified and lower stably stratified parts. The local convection cannot originate in the PA domain because the air layer belongs to the lower stably stratified part. A remarkable destabilizing effect of additional air layers has been revealed. For example, at the fixed solid fraction of 0.1, we achieve a 40-fold reduction of the critical Darcy-Rayleigh number in the APA domain by increasing the depth ratio from 0 to 0.5, and by 14 times in the AP domain and only by 3.5 times in the PA domain. The destabilizing effect enhances with increases in the solid fraction.
Numerical modelling of inflatable steel-tube rock bolt considering non-linear contact behaviour
Authors: Kim Kyeong-Cheol , Kim Ho-Jong , Kim Kang-Hyun , Shin Jong-Ho
Published: September 2023

Inflatable steel-tube rock bolts are useful as they can introduce a pull-out resistance immediately after installation and do not cause a loss of frictional force under the existing groundwater environment. The anchoring mechanism and pull-out resistance of the inflatable steel tube has been basically explained through theoretical studies. The contact behaviour between the tube and borehole rock is essentially geometrically non-linear and elasto-plastic, which cannot be properly considered in theoretical approaches. In this study, the contact behaviour of inflatable steel-tube rock bolts was investigated through a novel modelling based on the contact theory. A validating representative model test for an inflatable steel-tube rock bolts was performed and successfully reproduced through the contact modelling method. It was revealed that the contact behaviour differs significantly differ from theoretical assumptions. Parametric analyses were carried out to investigate the effect of influencing factors such as the diameter ratio, the elastic modulus and maximum installation pressure, which cannot be considered in the theoretical model. It was found that the state of full inflation is the stress turning point where the general tube behaviour changes from mainly plastic to elastic. The maximum contact stress was obtained immediately before full inflation.
Ingeniería SolidariaResearch article. https://doi.org/10.16925/2357-6014.2023.03.03 1 Lovely Professional University, India Email: bhuvanpuri1199@gmail.com ORCID: https://orcid.org/0000-0002-3098-7892 2 Lovely Professional University, India Email: rameshwar.20345@lpu.co.in ORCID: https://orcid.org/0000-0002-5369-7433 A review on the role of IoT, ai, and blockchain in agriculture & crop diseases detection using a text mining approach
Authors: Puri Bhuvan , Cambow Rameshwar
Published: September 2023

Introduction: This paper is the outcome of a review survey, “Role of IoT, AI and blockchain in agriculture and crop disease detection using a text mining approach,” done at Lovely Professional University in Punjab, India, in 2023. Problem: Agriculture is a crucial industry that contributes significantly to the economies of many nations. Crop diseases are one of the issues that create a barrier to agricultural development. Objective: Using machine learning, deep learning, image processing methods, the Internet of Things, and blockchain technology, this study provides a current summary of research done over the past years on disease identfication of various crops. Methodology: The text mining technique is applied to extract the related information from published papers and predict the following futuristic technologies to detect crop diseases early. Results: This paper also covers the various issues, challenges, and potential solutions. It also emphasizes the wide range of tools available for identifying crop diseases. Conclusion: This paper helps to extract valuable keywords through a text-mining approach and create a roadmap for another researcher. Originality: Applied text mining visualization techniques, such as word cloud and word frequency, to extract the keywords. Limitation: The literature survey only covers literature published prior to February 2023; it can be extended with more studies published soon.
Selective solid-phase reduction of iron in phosphorous oolite ores
Authors: Suleimen B. , Salikhov S. P. , Sharipov F. Sh. , Roshchin V. E.
Published: September 2023

Selective solid-phase reduction of iron and phosphorus in oolite ores of the Lisakovsky and Ayat deposits was experimentally studied. Using X-ray phase analysis, the phase composition of the initial ores and samples after reduction roasting was determined. Goethite, magnetite and quartz were found in the ores of both deposits. Phosphorus in the ore of the Ayat deposit is in the form of aluminum phosphate and iron hydrophosphate, and in the samples of the Lisakovsky ore – as a component of calcium hydrophosphate. Experiments on reduction roasting were carried out in a resistance furnace at 1000 °C with holding time of 5 h. After roasting in CO atmosphere, α-Fe appears in the samples, while phosphorus remains as a component of iron, calcium and aluminum phosphates. After roasting in a mixture with graphite, phosphorus is reduced by solid carbon from iron and calcium phosphates and passes into metal, but remains as a component of aluminum phosphate. Studies using microroentgenospectral analysis show that phosphorus content in the metal phase after reduction with solid carbon is 2.0 – 3.5 at. %. When CO is reduced in the atmosphere, phosphorus in the metallic phase is practically not detected. At the same time, the amount of residual iron in the oxide phase after carbon monoxide reduction significantly exceeds the amount of iron after reduction in a mixture with carbon. The experimental results confirm the possibility of selec­tive reduction of iron by carbon oxide CO without phosphorus reduction.
Formation of strategic priorities of industrial development of the Russian Federation as an innovative factor in overcoming crisis periods
Authors: Grinev S. A. , Kvint V. L.
Published: September 2023

The relevance of the study is determined by the need to search for innovative factors that contribute to the stability of the economy in times of crisis. The authors highly appreciates the role of intellectual innovations in overcoming crises in the economy. Focusing on the theoretical and methodological aspects of the formation of priorities for industrial development of the Russian Federation after the economic crisis of 2009, the authors hypothesized that changes in approaches to state management of economic processes were refl ected in regulatory documents and economic indicators, their analysis can point to the advantages and disadvantages of the existing institutional approach. The paper analyzes public management decisions in relation to the relevant economic indicators for the period from 2009 to 2021. It is determined that the main priorities of the state and economic policy of the Russian Federation during this period are innovative activities and the corresponding industrial policy. The choice of priorities is analyzed from the point of view of compliance with the author's methodology. The positive and negative dynamics of economic indicators as a consequence of the implementation of development priorities are studied, with an emphasis on crisis periods. Based on the results of the study, the authors argues that the choice of state development priorities had a positive impact on the stability of the economy, but the lack of integrity in strategizing did not allow achieving maximum effi ciency. This leads to the conclusion that a scientifi cally based institutional approach with the alignment of strategic priorities in a holistic national strategy can be a separate innovative factor of economic stability in times of crisis.
Prosecutors Prevention of Violations of Legislation Regulating Artificial Intelligence: Problem Statement
Authors: Karpysheva Yulia
Published: September 2023

Prevention of law violations is one of the key directions of crime counteraction. Non-criminal offences often create conditions for publicly dangerous actions, so it is necessary to pay special attention to their prevention within the framework of early prevention of crime. Procuratorial bodies of the Russian Federation are one of the key subjects involved in crime prevention, and procuratorial supervision over the observance of laws plays a leading role in this work. The author attempts to outline the problem of the early prevention of legal offences connected with the use of artificial intelligence in the Russian Federation. At present, the bodies specifically authorized to exercise control and supervision in this sphere have yet not been determined. Due to this, preventive work cannot be carried out by the prosecution authorities, whose main task is to supervise the observance of laws by other bodies, timely detect violations in their work and undertake measures to eliminate such violations, as well as the causes and conditions leading to them, neutralizing the accompanying criminogenic factors. Another problem, according to the author, is the absence of legal regulations of the use of artificial intelligence at the federal level, which, in its turn, makes it impossible both for the prosecutors office to exercise oversight, or for any other bodies to carry out preventive measures in this sphere. Due to this, and taking into account the significance of information technologies in the life of society and the state today, it is necessary to eliminate the outlined obstacles to preventive work in the sphere of artificial intelligences functioning.
The Formation of Criminal and Police Proceedings in the Russian Law of the XVIII - Early XIX Century
Authors: Minnikes Irina
Published: September 2023

The author researches the formation of the sectorial differentiation of legal norms regulating the investigation and analysis of criminal acts of different gravity in the Russian law of late XVIII - first half of XIX centuries. It is shown that Russian legislation of XIX century used two methods of formulating procedural norms that regulated the investigation, analysis, prevention and suppression of offences. It is suggested that the first method should be called a centralized one, as the norms of procedural character are contained in one part of the Law Code of the Russian Empire. An example of this is the systematization of the criminal procedure norms in Book II «On Criminal Court Proceedings», Vol. XV of this Code. Thus, the question of the existence of the criminal process as a sector of Russian law can be answered positively. The second method, which the author calls decentralized, means that procedural prescriptions are aligned with material norms and scattered throughout different parts of the Law Code of the Russian Empire. An example of this are the norms constituting a part of the police law - the police process. The legislation of the early XIX century categorized offences as either crimes or offences of little significance. Offences of little significance did not lead to criminal punishments, and their investigation did not require a full criminal procedure. Procedural actions in cases of little significance, as well as the activities of the police to prevent and suppress criminal actions, were regulated by a large number of legal prescriptions in the Russian law, which could be put together under a common name «the police process». In order to denote the degree of separateness of these norms in the Russian legislation, the author introduces the concept «the direction of legal regulation». It means a stable aggregate of accumulated and somewhat separate measures united by a common subject and key methods of influencing the society. The direction of legal regulation is the predecessor of the sector of law. The conducted research allowed the author to establish that by the XIX century the Russian legislator systematized the procedural norms on the investigation and analysis of crimes and offences of little importance as an independent branch - the criminal process, and the direction of legal regulation - the police process.
К демографической и социальной истории Черноземья: данные метрических книг и реестров населения в контексте исторических источников
Authors: Рязанов Влас Александрович
Published: September 2023

В статье автор рассматривает метрические книги и ревизские сказки черноземного села Снежеток за столетний период (1758-1862 гг.) в качестве объективного источника данных о социальной истории этой территории в XVIII-XIX веках. Они показывают сравнительно низкое формальное соблюдение как установлений Церкви (несоблюдение постов, высокая внебрачная рождаемость, наличие венерических заболеваний, случаи полигамии), так и гражданского законодательства (частые нарушения минимального брачного возраста), заметное откладывание женитьбы мужчинами при важности патрилинейного родства (давние и устойчивые фамилии), миграционную подвижность и практику сильного завышения возраста пожилых умерших. Данная картина в самой плодородной части Центральной России слабо соотносится с классическими чертами устойчивых земледельческих сообществ, но соответствует культурным реалиям, унаследованным от пионерного военного населения смешанного этнического происхождения, которые подтверждаются многочисленными историческими материалами. Автор рассчитывает демографический вес Черноземья в XVII-XXI веках и на основе его большой величины (40% населения Центральной России в XIX веке) ставит под сомнение утверждение о преимущественно земледельческом характере русского дореволюционного общества в целом. Рассмотрение демографической истории Черноземья до и после хронологических рамок массива метрических книг позволяет сделать вывод об «эффекте колеи» и сильной зависимости социально-экономической динамики от унаследованного культурного базиса.
Swimming and aqua pole-walking
Authors: Miyashita Mitsumasa
Published: September 2023

The drag forces were measured during towing swimmers in static prone positions at various speeds. The drag force mostly depends on towing speed, and body position; the head above water or the head underwater.
Use of flow cytometry (Novocyte Advanteon) to monitor the complete life cycle of the parasite Amoebophrya ceratii infecting its dinoflagellate host v1
Authors: Szymczak Jeremy
Published: September 2023

The parasite belongs to Amoebophrya ceratii (Amoebophryidae or MALVII, which stands for Marine Alveolate Group II, Syndiniales, Dinoflagellata, Alveolata), a complex species that includes intracellular marine parasites infecting and ultimately killing other dinoflagellates. During its life cycle, a free-living parasitic cell (known as dinospores, measuring 2-5 µm) penetrates its host, consumes it, and eventually undergoes sporulation. In this study, we present a method for identifying and quantifying the different stages occurring during the entire infective process of this parasite, using flow cytometry (NovoCyte Advanteon, ACEA Biosciences), equipped with two lasers (405 and 488 nm). This document presents the different setup for the acquisition, analysis, and data export. Origin of strains Strains of both the host and parasite have been isolated from the Penzé estuary, located in the north-west of France in the English Channel (coordinates: 48°37’N; 3°56’W). The Amoebophrya ceratii A120 strain (RCC4398) was originally derived from a single infected cell of Heterocapsa triquetra collected on June 13th, 2011, and subsequently incubated with exponentially growing H. triquetra (primary host HT150, RCC3596). Starting from April 23rd, 2012, A120 has also been maintained in Scrippsiella acuminata (strain ST147, RCC 1627), formerly known as Scrippsiella trochoidea as described by Kretschmann et al. in 2015. The host strain ST147 was established from the germination of a single cyst collected from sediment in 2007. Strain A120 is a parasite belonging to MALVII-Clade 2, ribotype 4, based on the nomenclature of Guillou et al. (2008) and Cai et al. (2020). All strains have been deposited at the Roscoff Culture Collection, https://roscoff-culture-collection.org/.
Assessment of a Carbon Fiber Prosthetic Running Blade for Enhanced Reliability
Authors: Siddiqui Md Irfanul Haque , Alnaser Ibrahim Abdullah , Alluhydan Khalid
Published: September 2023

This study focuses on the development of a reliable prosthetic running blade primarily composed of carbon fiber. The reliable performance of novel prosthetic running blades has been evaluated by mechanical testing and finite element numerical modeling. The experimental analysis confirmed that these blades exhibit superior suitability for high-impact activities, demonstrating reliable load-bearing capacity and effective shock absorption properties. The tensile testing exhibited a linear elastic behavior of the composite material up to a strain of 0.075 mm/mm. Further, it was found that stress concentration areas and fracture points within the blade structure. Furthermore, numerical results revealed a maximum deflection of 29.60 mm that the blade can achieve. The kinetic energy loss during impact demonstrated an 8.5% decrease in blade kinetic energy, with the highest loss occurring at Vy = 30 m/s. Ultimately, this research aims to enhance the reliability, durability, and safety of prosthetic running blades, empowering athletes to reach new heights in sports.
Claves diagnósticas en el paciente adulto con derrame pleural: revisión narrativa
Authors: Forero-Saldarriaga Santiago
Published: September 2023

El derrame pleural se define como la acumulación anormal de líquido en el espacio pleural, que se produce por el aumento en la producción o disminución en su drenaje. Es una entidad frecuente en la práctica clínica y obedece a múltiples causas, las cuales varían de acuerdo con la epidemiología local, los antecedentes y el contexto clínico. Es determinante el análisis del líquido pleural, cuando esté indicado, así como otras ayudas diagnósticas teniendo en cuenta la presentación clínica con énfasis en las condiciones comórbidas y las infecciones. De estas últimas, se destaca la tuberculosis y la neumonía, entidades bastante frecuentes en nuestro medio. El tratamiento va dirigido a la causa de base, aunque hasta en el 25 % de los pacientes no se identifica una causa evidente.
Compromiso cardíaco por amiloidosis AL: La desemejanza como atributo. Reporte de 3 casos
Authors: Rondón-Carvajal Julián , Betancur-Salazar Kelly Johanna
Published: September 2023

La amiloidosis AL (antes denominada amiloidosis primaria) es una entidad sistémica poco frecuente, con incidencia desconocida en el mundo, que puede llegar a presentar compromiso cardíaco en casi la mitad de los pacientes, llevando a una cardiomiopatía restrictiva por depósito de tejido amiloide. A continuación, presentamos 3 casos de pacientes que consultaron por falla cardíaca aguda y síncope, en quienes finalmente se confirmó el diagnóstico de amiloidosis AL. Al final, se realiza una breve revisión de la literatura, enfatizando en los elementos clínicos para un diagnóstico temprano.
Evaluación de la prueba de avidez para el seguimiento de niños tratados por toxoplasmosis congénita durante el primer año de vida
Authors: Caro-Garzón Jesús David , Gómez-Henck Clara , Jaramillo-Giraldo Tatiana , Cifuentes-Botero José Mateo , Gómez-Marín Jorge E.
Published: September 2023

Objetivo: determinar la utilidad de la prueba de avidez en el seguimiento de los pacientes diagnosticados con toxoplasmosis congénita a través de la evaluación de su comportamiento en el tiempo.

Metodología: estudio retrospectivo a partir de los datos en historias clínicas de niños que tuvieron confirmación diagnóstica y tratamiento para toxoplasmosis congénita, realizado en consulta de toxoplasmosis, tercer nivel de referencia en el centro de salud de la Universidad del Quindío. Se estudiaron 21 niños que fueron seleccionados de una cohorte inicial de 168 pacientes, reclutados en los programas de tamizaje prenatal y los programas de prevención o niños que acudieron para el diagnóstico neonatal.

Resultados: no se encontró relación estadísticamente significativa entre el porcentaje de avidez baja en el primer mes y haber recibido tratamiento prenatal (p = 0,47). Tampoco entre la primera y los niveles de IgG o los meses de vida, a pesar de haber recibido tratamiento posnatal. Sin embargo, al estudiar específicamente el grupo de niños de 5 meses de edad, se encontró una correlación significativa con los niveles de IgG anti-Toxoplasma (p = 0,01).

Conclusión: en esta cohorte de niños colombianos con toxoplasmosis congénita se encontraron los mismos resultados reportados en series previas con un mayor número de casos en Italia. La avidez no mostró ser útil para el seguimiento de los niños con toxoplasmosis congénita.
Alta sensibilidad a la mupirocina en aislados de Staphylococcs aureus que colonizan pacientes en hemodiálisis en una unidad renal de Medellín, Colombia
Authors: Torres-Cuadros Yesid Leandro , Vélez-Montoya Juan Guillermo , Vanegas-Múnera Johanna Marcela , Roncancio-Villamil Gustavo Eduardo , Jiménez-Quiceno Judy Natalia
Published: September 2023

Objetivo: describir el porcentaje de resistencia a la mupirocina y a otros antibióticos en aislados de Staphylococcus aureus que colonizan pacientes en hemodiálisis.

Métodos: estudio descriptivo en el que se incluyeron pacientes en hemodiálisis en una unidad renal de Medellín. La colonización por S. aureus fue evaluada en las fosas nasales y en la piel. La identificación bacteriana se realizó por PCR y la sensibilidad antibiótica se determinó por el sistema automatizado VITEK-2 y por el método E-test. Las características clínicas de los pacientes fueron evaluadas con la historia clínica.

Resultados: se incluyeron 210 pacientes, de estos el 50,5 % (n = 106) fueron mujeres, con una mediana para la edad de 62 años (RIC 51,87-71,13). De las características clínicas se destacó el uso frecuente de antibióticos: 59 % (n = 124) y la historia de hospitalización: 69 % (n = 145). El porcentaje de colonización por S. aureus fue de 33,8 % (n = 71) y el sitio más frecuente de colonización fue las fosas nasales (19 %; n = 40). Todos los aislados fueron sensibles a la mupirocina por el método de VITEK-2. Sin embargo, un aislado presentó resistencia de bajo nivel a la mupirocina por E-test. La colonización por aislados resistentes a meticilina (SARM) fue de 4,8 % (n = 10) y estos presentaron, principalmente, resistencia solamente a la oxacilina (58,3 %; n = 7).

Conclusión: la alta sensibilidad a la mupirocina en aislados de S. aureus colonizantes sugiere su uso como terapia profiláctica en pacientes en hemodiálisis con alto riesgo de infección. Es importante fortalecer los programas de uso racional de antibióticos para evitar la diseminación de mecanismos de resistencia a estos y a otros en las unidades renales.
Sarcoidosis asociada a panuveítis en el área de un tatuaje: reporte de caso
Authors: Chavarriaga-Restrepo Andrés , López-Amaya Juan Esteban , Mesa-Navas Miguel Antonio , Velásquez-Franco Carlos Jaime
Published: September 2023

Antecedentes: la sarcoidosis es una de las reacciones cutáneas asociadas con los tatuajes. Lo más frecuente es que se presente una afección sistémica; dentro de ésta, el compromiso por uveítis y las reacciones sarcoidales asociadas a los tatuajes han sido poco descritas.

Caso clínico: hombre de 27 años con cuadro clínico de seis meses de evolución constituido por malestar general, fiebre subjetiva, escalofríos, mialgias, artralgias, tos con expectoración hemoptoica y edema en los miembros inferiores. Se encontró ojo izquierdo rojo, disminución de la agudeza visual y pápulas que infiltraban uno de los tatuajes que se había realizado seis meses antes en el brazo derecho y antebrazo izquierdo.

Conclusión: la sarcoidosis asociada a los tatuajes es una condición que requiere de un alto índice de sospecha; donde la infiltración del tatuaje debe hacer pensar al clínico en el diagnóstico para realizar la búsqueda activa del daño orgánico visceral, mucho más en un paciente con uveítis que puede llevar a la ceguera. Aunque inusual, existe esta triple asociación: tatuaje, sarcoidosis sistémica y panuveítis.
Tomografía abdominal sin contraste oral: evaluación de su rendimiento en el dolor abdominal agudo no traumático
Authors: Castrillón Germán Alberto , Aguirre-Peña Juan Felipe , Saldarriaga María Fernanda
Published: September 2023

Objetivo: evaluar el rendimiento diagnóstico de la tomografía abdominal sin medio de contraste oral en pacientes con dolor abdominal.

Materiales y métodos: se incluyeron tomografías de pacientes con dolor abdominal entre el 1 de septiembre y 31 de diciembre del 2015 en el Hospital Universitario San Vicente Fundación. Se analizó el desempeño de las tomografías con o sin contraste oral y se consideró como prueba de referencia el resultado diagnóstico definitivo en la intervención quirúrgica o por diagnóstico clínico. Se calculó la sensibilidad, especificidad y los valores predictivos positivos y negativos con intervalos de confianza del 95%.

Resultados: fueron evaluadas un total de 128 tomografías de abdomen, 91 con contraste oral y 37 sin él. La tomografía sin contraste oral tuvo una sensibilidad y especificidad muy similar a la que sí lo tenía, con valores de 84% y 91,6%, respectivamente.

Conclusión: el rendimiento global de la tomografía con contraste oral fue similar a la que no lo tenía, con valores cercanos al 90%. La adquisición de la tomografía con contraste oral tomó casi 3 veces más tiempo que el requerido en los estudios sin contraste oral.
Historia de la penicilina: más allá de los héroes, una construcción social
Authors: Giraldo-Hoyos Nicolás
Published: September 2023

El hecho científico conocido como “penicilina” se ha considerado tradicionalmente como el producto del ingenio de Alexander Fleming, ganador del Premio Nobel por descubrir esta “droga milagrosa”. Apartándose de esta idea popular, se hace necesario resaltar el desarrollo de la penicilina como un constructo social, producto del trabajo invaluable de varios científicos, sumado a un contexto social excepcional que motivó la voluntad política y el apoyo de la industria farmacéutica; en ausencia de cualquiera de estos, la penicilina no sería lo que significa hoy para nosotros o, simplemente, no existiría en el arsenal terapéutico. Los conceptos epistemológicos de “estilo de pensamiento” y “colectivo de pensamiento” como fundamentos en la construcción del conocimiento, presentes en la obra epistemológica de Ludwick Fleck, apoyan la conclusión, a partir del recuento histórico, de la necesidad de apartarnos de la penicilina como el producto de un descubrimiento de un único héroe, para verla como una construcción social, que además es un ejemplo clásico de serendipia. La penicilina, además, tiene otras facetas menos conocidas históricamente como el uso de ella de manera cruda, producida y usada por médicos generales, o la búsqueda de información para su producción durante la segunda guerra mundial; estas se abordan en este breve recuento histórico.
Characterization of decontamination procedure of beef carcasses at slaughterhouses in the province of Antioquia, Colombia
Authors: Silva Jorge Arturo Fernández , Sánchez-Acevedo Mauricio , Peña Serna Carolina , Garay Pineda Francisco J.
Published: September 2023

BACKGROUND: Beef slaughterhouses must use a carcass decontamination procedure to control pathogens and thus prevent foodborne diseases transmitted by meat. OBJECTIVES: This study aimed to characterize beef carcass decontamination procedures at slaughterhouses located in the province of Antioquia (Colombia). All the slaughterhouses were open, registered, and approved by Invima (Instituto Nacional de Vigilancia de Medicamentos y Alimentos in Spanish) at the time of the study. METHODS: This descriptive study collected information from 23 beef slaughterhouses between July 2019 and April 2021 through documentary reviews and visits to slaughterhouses, using forms and questionnaires. RESULTS: The study allowed the characterization of the procedures used to decontaminate beef carcasses, showing that the chemical disinfection of the carcasses is used to control microorganisms in at least 73.9% of the slaughterhouses analyzed. According to secondary sources, it was found that most of the slaughterhouses are small (slaughter volume <50,000 heads per year); 10 of them use citric acid, lactic acid, peracetic acid, and a mixture of organic acids in concentrations between 900 and 1,200 ppm, 1.5 and 1.7%, 180 and 190 ppm, and 900 and 1,200 ppm, respectively, as carcass disinfectants and according to the technical data sheet of the product. During the visits and through the application of the questionnaire, it was found that the 12 slaughterhouses had implemented chemical disinfection which is not scientifically based, using manual devices as an intervention method to control pathogenic microorganisms. It was found that the type of company, slaughter volume, and the lack of financial resources are the determining factors in the selection of decontamination procedures. The validation of the beef carcass decontamination procedures in the different slaughterhouses in the study was demonstrated. CONCLUSIONS:Although it was established that at least one decontamination procedure, such as chemical disinfection, is used in the slaughterhouses of study, this option is not supported by scientific or technical evidence. The findings support the need for improvements in the slaughterhouses of the province of Antioquia, including the improvement of surveillance programs to reduce pathogens in the meat chain effectively.
TAP block comfort for lower abdominal surgery in pediatric patients
Authors: ÖZKAN Feyza
Published: September 2023

Purpose: The aim of this study was to examine the effect of The transversus abdominis plane (TAP) block after lower abdominal surgery on pain severity and additional analgesic requirement in a pediatric patient group.

Materials and Methods: In this retrospective study, 46 ASA I children aged 2-18 years undergoing abdominal surgery were divided into two groups. Group T (n: 20) patients who were under the general anesthesia received ultrasound-guided TAP block with 0.5 mL/kg of 0.25% bupivacaine immediately after the operation. Group O (n: 26) patients were administered intravenous (I.V.) 2 µcg/kg opioid (fentanyl) analgesia after recovery from general anesthesia. The patients were taken to the post-anesthesia care unit (PACU) for recovery and initial pain observation. Patients pain was assessed by using the Visual Analogue Scale (VAS) score within the first 24 hours following surgery.

Results: The incidence of the additional analgesic requirement in the TAP block(%15) group was statistically significantly lower than in the I.V. opioid group(%65). There was a difference between the first analgesic requirement and the discharging time according to TAP block administration, but it was statistically insignificant. The VAS scores at 4 hr and 8 hr in the TAP block group were statistically significantly lower than in the IV opioid group(4.VAS:4.90±1,21 5.90±0.85; 8.VAS:4.05±0.76 3.10±0.85). The VAS scores at postoperative 2 hr were decreased in both groups. However, the decrease in the VAS score at 2 hr was greater in the TAP block group.

Conclusion: TAP block was superior to IV opioids in reducing additional analgesic requirements in pediatric patients undergoing abdominal surgery. It will contribute further to early discharging a patient as it allows early mobilization.
Serum asprosin and trimethylamine oxide levels in polycystic over syndrome with and without metformin treatment
Authors: KARAKULAK Koray , ÖNALAN Erhan , YAKAR Burkay , DÖNDER Emir , KİLİNC Faruk , GÜRSU Mehmet Ferit
Published: September 2023

Purpose: The presence of a potential relationship between metabolic diseases and hormones and the intestinal flora has recently gained attention. Levels of asprosin and trimethylamine oxide (TMAO) may be associated with polycystic over syndrome (PCOS), which is a metabolic disease. The present study aims to investigate the potential relationship of PCOS with serum asprosin and TMAO levels.

Materials and Methods: This cross-sectional study included 30 PCOS patients on metformin, 30 PCOS patients not receiving treatment, and 30 healthy controls. The demographic, glucose, insulin resistance, lipid, and hormone profiles of the participants were analyzed. Serum asprosin and TMAO levels were investigated with the ELISA method.

Results: Patients with PCOS had higher BMI, serum glucose, triglyceride, ALT, insulin levels, and HOMA-IR scores compared with controls. The serum testosterone level was 28.1 ng/dl in the control group, 33.3 ng/dl in the PCOS group receiving metformin and 48.0 ng/dl in the untreated PCOS group, and there was a statistically significant difference. Neither serum asprosin nor TMAO levels were significantly different when compared between the three groups.

Conclusion: Serum asprosin and TMAO levels of individuals with PCOS and healthy controls were not significantly different. The receipt of metformin treatment by PCOS patients did not have a significant relationship with serum asprosin and TMAO levels.
The impact of maltreatment on symptom severity in patients with attention deficit hyperactivity disorder
Authors: SUZER GAMLİ İpek , YOLGA TAHİROĞLU Ayşegül
Published: September 2023

Purpose This study aimed to compare the impact of maltreatment on the subtype, comorbidity, sociodemographic characteristics, and psychometric characteristics of attention deficit hyperactivity disorder (ADHD).

Materials and Methods: The study participants included 150 treatment-naïve children with ADHD with (n=75) and without (n=75) a history of maltreatment by parents. A sociodemographic form, the Conners Parent Rating Scale (CPRS), the Conners Teacher Rating Scale (CTRS), the Family Assessment Device (FAD), and the Stroop Form were applied.

Results: Earlier referral, peer discord, and lower parental age were frequent in the maltreated group, while the maternal employment rates were significantly lower. ADHD-combined type and comorbid oppositional defiant disorder were significantly higher in the maltreated group. The CPRS and FAD scores were also significantly higher).

Conclusion: A higher incidence of destructive behavioral patterns may increase the risk of maltreatment. Families of children with hyperactivity and defiant characteristics may have difficulties in managing behavioral problems and may exhibit domestic violence, with the Multidisciplinary approaches, including parental education programs and social investigation, should be considered.
Analysis of telomere length in patients with COVID-19 and investigation into its relationship with clinical- demographic data
Authors: SAVRUN Atakan , DİRİCAN Ebubekir
Published: September 2023

Purpose: Novel coronavirus disease 2019 (COVID-19) is an infectious disease unknown before the 2019 outbreak in Wuhan. This study evaluated telomere length in COVID-19 (+) and (-) samples with clinical-demographic parameters.

Materials and Methods: DNA was isolated from COVID-19 (+) (n=70) and (-) (n=70) patients. Telomere length was determined by real-time-PCR (RT-PCR). The 2–∆∆Ct method was used to analyze the telomere length of the samples.

Results: There were significant differences in creatinine, LDH, ferritin, WBC, NEU and CRP in COVID-19 (+) patients compared to COVID-19 (-) patients. The NEU/LYM (or N/L) ratio was found higher in the patients with COVID-19 (+), than in COVID-19 (-). On the other hand, our COVID-19 (+) patients (mean±std:0.93±0.58) had significantly shorter telomere lengths than the COVID-19 (-) (mean±std:1.26±0.76). Moreover, COVID-19 (+) male patients (mean±std:1.06±0.50) had longer telomere length than female patients (mean±std:0.76±0.54). Telomere length was significantly shorter in patients with COVID-19 (+)with high blood urea nitrogen (BUN), high creatinine, high hematocrit, high NEU levels, normal platelets (PLT), and low WBC levels.

Conclusions: Our findings suggest that telomere length and blood parameter levels influence the severity of COVID-19. Blood parameters differed in patients with COVID-19 (+) and COVID-19 (-). As a result, increasing the number of similar studies in the future can demonstrate the significance of our findings.

Keywords: COVID-19, Telomere length, RT-PCR, NEU/LYM, blood
Evaluation of the effects of body and auricular acupuncture combination therapy in obesity control: a retrospective study
Authors: YILDIRIM Duygu İlke
Published: September 2023

Purpose: The aim of this study is to retrospectively evaluate the effects of body (abdominal) and auricular acupuncture combination therapy on anthropometric measurements and blood parameters in obesity control.

Materials and Methods: This study is a descriptive, cross-sectional and retrospective study. This study was carried out by retrospectively scanning the patient files of the patients who applied to the obesity center between 01.05.2019 and 15.02.2020 and wanted to have acupuncture.

Results: There are 10 points selected: Shenmen (HT7, spirit gate), point zero, small intestine, large intestine, stomach, esophagus, mouth, appetite control (hunger), antidepressant and spleen point. The abdominal acupuncture points applied to the patients for the treatment of obesity are shown in this study. There are 6 points selected: ST 25, ST 26, REN 12 (CV12), REN 10 (CV10), REN 6 (CV6), REN 4 (CV4). The results show that combined ear and abdominal acupuncture resulted in significant weight loss in all participants in the acupuncture group. The mean high-density lipoprotein cholesterol (HDL-C) mean scores of the patients who underwent acupuncture were significantly higher whereas the mean low-density lipoprotein cholesterol (LDL-C) scores was significantly lower than the patients who did not receive acupuncture.

Conclusion: Ear and abdominal acupuncture applications applied for three months for weight loss in obese individuals provided significant weight loss, along with a significant decrease in waist/hip ratio and improvement in all other blood parameters.
Histone deacetylase inhibitory and antioxidant activities of some ethanolic plant extracts: A novel therapeutic approach for cancer
Authors: DAĞSUYU Eda , YANARDAĞ Refiye
Published: September 2023

Purpose: The aim of this study was to evaluate histone deacetylase inhibitory and antioxidant activities of some ethanolic plant extracts.

Materials and Methods: In this study, the inhibitory effects of ethyl alcohol extracts prepared from various plants and some chemical compounds on histone deacetylase activity were investigated. In addition, the antioxidant activity of plant-derived active substances, which have had an important value in alternative medicine in recent years, has been determined to replace chemicals.

Results: All the plant extracts and chemical substances used in the study showed histone deacetylase inhibitory effect (with IC50 range of 0.000078-319.0 µg/mL) and antioxidant activity. The results indicated that the percentage of histone deacetylase inhibition and antioxidant activities increased with increasing concentrations of the plant extracts and chemical compounds.

Conclusion: These plant extracts which are potential sources of histone deacetylase inhibitors may be appropriately used as an alternative support to drug treatment rather than the use of toxic chemicals.