bluuebunny/crossref_metadata_2025 huggingface dataset:
MOTIVATION AND TEACHERS’ PERFORMANCE: EMPIRICAL EVIDENCE FROM PRIMARY LEVEL
Authors: Zahid Muhammad Sharif  , Rizwan Ali  , Mudassar Hussain Zahid  , Dr. Ahsaan Siddique
Published: February 2025

The current study investigated the relationship between motivation and teachers’ performance at the primary school level in Punjab, Pakistan. The research was descriptive-correlational and quantitative in nature, with a positivistic perspective. Participants were chosen as samples using a multi-stage random sampling method. The sample included 414 male and female primary school teachers. For data collection, two closed-ended questionnaires were used. A pilot study was carried out to confirm the research instruments’ validity and reliability. Inferential statistics such as Pearson r, independent sample t-test, linear regression, and one-way ANOVA were used to examine the data. The findings of the study demonstrated that motivation was positively correlated with teachers’ performance. The study’s findings revealed that teachers’ motivation and performance differed based on their teaching experience. The findings also demonstrated that motivation had a positive significant influence on their primary teachers’ performance. Teachers advised that a substantial paradigm shift in Pakistani education policy on factors such as school governance, remuneration, safety and security, as well as assessments and evaluations, be implemented in order to enhance performance. Additionally, school administrations should give enough resources such as incentives, prizes, excellent Communication, moral assistance, psychological encouragement, and compensation increases are all used to ensure that the instructional staff provides outstanding educational experiences and high performance in order to develop the relevant system of education.
BI-DISTANCE PROCEDURE FOR EVALUATING THE TOPOLOGICAL INDICES FOR RHOMBUS OXIDE NETWORK
Authors: Muhammad Imran  , Muhammad Rizwan Wahala  , Muhammad Nawazish Zaman  , Saima Mushtaq  , Zunera Shoukat
Published: February 2025

This study explores the fractal nature of rhombus oxide network, leveraging molecular structure descriptors to correlate chemical structure with biological activity in pharmacology. By translating networks into graphical forms and utilizing degree-based topological indices, we calculate various indices (Randić, geometric arithmetic, atom bond connectivity, and more) and their polynomials for rhombus graphs using Mathematica. This computational approach enables the estimation of fractal, thermodynamic, and physicochemical aspects of chemical structures, informing configuration, impact resistance, and design in technical and scientific advancements. Our results provide a comprehensive understanding of chemical graph theory, facilitating the correlation of chemical structure with biological activity and contributing to significant advancements in pharmacology and materials science.
Rua do Sacramento (1903)
Authors: De Paula Pereira Nelson
Published: February 2025

Este artigo examina a primeira obra realizada pelo prefeito Pereira Passos: o alargamento e prolongamento da Rua do Sacramento (1903), sob uma perspectiva historiográfica e urbanística. Essa obra marcou o início das transformações urbanas da "Reforma Passos", sendo fundamental para compreender as reformas que moldaram o Rio de Janeiro ao longo do século XX e refletir sobre os padrões e impactos de intervenções urbanas posteriores. O estudo, baseado na análise de fontes primárias e secundárias, revela que as intervenções urbanas no Rio de Janeiro, embora modernizadoras, perpetuaram desigualdades, destacando a necessidade de reformas com modernidade, justiça social e integração urbana.
Peran Manusia Terhadap Lingkungan Hidup Dalam Al-Qur’an Perspektif M.Quraish Shihab (Studi Tematik Tafsir Al-Misbah)
Authors: Nurul Fahmiyah  , Fathoni
Published: February 2025

The role of humans in the environment is one of the important themes in Islamic teachings. The Qur’an, as the holy book of Muslims, provides clear guidance on the relationship between humans and the environment. M. Quraish Shihab, through his monumental work, Tafsir Al-Misbah, provides a comprehensive and in-depth explanation of this concept. This study aims to examine the role of humans in the environment according to M. Quraish Shihab’s perspective, as outlined in Tafsir Al-Misbah. The method used in this study is a thematic study, which focuses on the verses of the Qur’an that discuss the environment and how M. Quraish Shihab interprets them. The results of the study show that M. Quraish Shihab emphasizes the importance of the role of humans as caliphs on earth, who have a great responsibility to protect and preserve the environment. The concept of the caliphate includes the obligation not to be excessive in using natural resources, maintaining the balance of the ecosystem, and acting fairly and wisely in managing the environment. In addition, M. Quraish Shihab also highlighted the importance of ecological awareness in every human action. He emphasized that environmental damage is the result of irresponsible human behavior, and that improvement can only be achieved through behavioral changes in accordance with Islamic teachings. This study is expected to contribute to efforts to understand and apply the values ​​of the Qur'an in the context of environmental protection, as well as inspire Muslims to be more concerned and responsible for the environment.
Effect of tax knowledge on individual taxpayers compliance
Authors: To Van Tuan
Published: February 2025

The objective of the study is to analyze the impact of tax knowledge factors, including tax reporting knowledge, tax calculation knowledge, and tax payment knowledge, on personal tax compliance. Data were collected in Hai Phong City through 326 valid survey questionnaires, which were subjected to quantitative analysis using SPSS software and the OLS regression analysis method. The research results showed that all three factors related to tax knowledge significantly impact personal income tax compliance behavior. The study also provides implications for improving tax awareness among individuals, thereby enhancing personal income tax compliance among the people of Hai Phong in particular and the nation as a whole in the future.
Gender Stereotype Reduction Framework Lessons From An Early Childhood Development Play Centre Mooiplaats School Chipinge Zimbabwe
Authors: Mhlanga Gerry , Gumbo Shepherd
Published: February 2025

Gender stereotyping manifests in all the communities of the world and it remains a contemporary social problem. Drawing from the observed gendered play material usage at Mooiplaats Primary School in Chipinge peri-urban, Zimbabwe this article unpacks the motivation for the practice and proposes a framework which could be used to reduce it. The study adopted the qualitative research approach and data were collected by observing 15 boys and 15 girls in Early Childhood Development using play materials and by interviewing purposively sampled 10 parents/guardians of ECD learners, two ECD teachers and the Teacher-in-Charge of infants. Besides, play material inventories were analysed to establish purchase preferences and the patterns of usage. All this was done basing on the lenses of Oakely‘s Gender Socialisation Theory. Emerging themes indicate that biological and cultural underpinnings influence the children‘s social environment comprising families, peers, media, schools, inter-alia, to recommend some gender specific play materials. Gender can be reduced through understanding its source, how it is practised and by appreciating the benefits of its reduction. The GSRF proposed is undergirded by sources of gender, followed by gender practices, gender reduction initiatives and benefits of gender reduction. Community surveillance is necessary to see through its implementation
Unlocking Performance Excellence And Impact In The Strategic Human Resource Training And Development In The Zimbabwe Republic Police
Authors: Tembo Evans Bonjisi , Bhebhe Thomas Brighton , Kuda Grace Portia , Madzimure Ngorora
Published: February 2025

This study explores the influence of strategic human resource training and development on performance excellence within the Zimbabwe Republic Police (ZRP), with the aim of unlocking optimal performance in the security services sector. The research was inspired by a noticeable deterioration of police performance across the country, public outcry and many newspaper reports on alleged corrupt tendencies and poor service delivery within the rank and file of the ZRP. The study adopted a mixed methods approach with a pragmatic philosophy. The target population was 210 police officers stationed at the Police General Headquarters (PGHQ) in Harare. Data were collected using questionnaires (n=136) and interview schedules (n=3). Quantitative data were analysed using the Statistical Package for Social Sciences (SPSS) Version 23.0, while qualitative data were analysed using the maticanalysis. Research results reveal that strategic human resource training and development programmes have a positive significant influence on employee performance in the ZRP. The research also established challenges constraining effective implementation of strategic human resource training and development in the Zimbabwean security services sector, notably lack of infrastructure, lack of training facilities, limited access to technology, limited e-learning resource, and high staff turnover, among others. The study, therefore, recommends that the ZRP should increase its investment in strategic human resource training and development programmes, as this would help to enhance the human capital of police officers, leading to improved performance excellence.
Teaching biomedical terminology using binary texts: linguocognitive and translation aspects
Authors: Latishev Kirill Igorevich
Published: February 2025

The purpose of the study is to form language competence as one of the main factors of professional growth of a future specialist. In particular, the research is based on the terminology of the field of biomedical engineering. Therefore, they need to be organized in order to simplify the definition process, to effectively highlight specific meanings and their translations, which in turn will allow scientists to explore certain phenomena and concepts with extraordinary accuracy. The article examines the peculiarities of cognitive and translational aspects of studying English and Russian terminology of biomedical engineering. It is noted that the specialized language of such an interdisciplinary field as biomedical engineering contains concepts that concentrate specific knowledge of technical, medical and topically scientific experience. In cognitive linguistics, concepts are considered in connection with the background knowledge. The specialized language of biomedical engineering is presented as a cognitive-communicative organization of concepts, notions and related terms in such highly specialized fields as bioinstrumentation, biomedical cybernetics, biomechanics, system physiology, rehabilitation engineering, diagnosis of diseases and disorders, etc. Translators should always take into account the following context criteria in the translation process: linguistic context, situational context and cognitive context. Based on the comparative analysis of binary texts – texts of the same genre and issue – the concept “sleep disturbance” is considered as a certain matrix of the terminological base of the concepts of the specified issue and basis for compiling highly specialized thematic mini-dictionaries. We must find as many unifying characteristics as possible, organizing the terms into conceptually similar groups, linking them with certain research methods, etc.
Thickness and doping-dependent properties of Li-doped NiO thin films for rectification effect of pn junction
Authors: WANG Lei  , ZHOU Tong  , HUA Enda  , LIU Zhongliang  , LI Bing  , LIU Qinzhuang  ,   Anhui Province Industrial Generic Technology Research Center for Alumics Materials, School of Physics and Electronic Information, Huaibei Normal University, Huaibei, Anhui 235000, People's Republic of China
Published: February 2025

Transparent conducting oxides (TCOs) are crucial materials in optoelectronics, yet p-type TCOs are less studied compared to n-type TCOs. NiO as a typical p-type TCO shows promising potential for transparent optoelectronic devices. In this study, we successfully fabricated LixNi1-xO thin films with varying thicknesses and Li doping levels on MgO(001) substrates using pulsed laser deposition. The results demonstrate that both increased thickness and Li doping levels reduce the resistivity of the films, with the maximum optical bandgap observed at a thickness of 50 nm and 3% Li doping levels. Based on the control of physical properties through film thickness and Li doping, p-type LixNi1-xO with the largest bandgap were selected to construct transparent electronic devices with n-type La-doped ASnO3 films. I-V tests confirmed the rectification properties of the heterostructures, successfully demonstrating the formation of pn junctions. This work enhanced the potential applications of transparent electronic devices by integrating p-type NiO with n-type ASnO3.
Unboxing Japanese Videogames
Authors: Roth Martin
Published: February 2025

A new perspective on the spatial complexity and plurality of Japanese videogames.

Unboxing Japanese Videogames uncovers the complex and plural spatialities of commercial videogames published in Japan between 1985 and 2015. Rejecting the “boxing” inherent in the phrase “Japanese videogames,” Martin Roth explores a series of spatialities that unfold in videogame production and distribution. The book develops a notion of spatialization that is applied in the analysis of contents or genre distributions in Japan, the US, the UK, Germany, and France, the distribution of videogame works across different important markets, the geography of actors involved in videogame production and their gradual spatialization over time, and the functional spatialization of game production across a diverse range of platforms.

This book is the first English-language study to provide an overview of the subject and also the first to explore the spatial history of FromSoftware games. It stands out because it does so quantitatively, offering a macro-perspective on the field of commercial videogames instead of relying on sales statistics or case studies. In addition to a wide range of related scholarship in English, the book engages actively with scholarship and other relevant resources in Japanese. Over thirty visualizations make the findings of the book tangible and invite the reader to explore the spatial complexity of commercial videogames further.
Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus
Authors: Xiang Qiwang , Wouters Camille , Chang Peixi , Lu Yu-Ning , Liu Mingming , Wang Haocheng , Yang Junqin , Pekosz Andrew , Zhang Yanjin , Wang Jiou
Published: February 2025

SARS-CoV-2 infection poses a major threat to public health, and understanding the mechanism of viral replication and virion release would help identify therapeutic targets and effective drugs for combating the virus. Herein, we identified E3 ubiquitin-protein ligase Itchy homolog (ITCH) as a central regulator of SARS-CoV-2 at multiple steps and processes. ITCH enhances the ubiquitination of viral envelope and membrane proteins and mutual interactions of structural proteins, thereby aiding in virion assembly. ITCH-mediated ubiquitination also enhances the interaction of viral proteins to the autophagosome receptor p62, promoting their autophagosome-dependent secretion. Additionally, ITCH disrupts the trafficking of the protease furin and the maturation of cathepsin L, thereby suppressing their activities in cleaving and destabilizing the viral spike protein. Furthermore, ITCH exhibits robust activation during the SARS-CoV-2 replication stage, and SARS-CoV-2 replication is significantly decreased by genetic or pharmacological inhibition of ITCH. These findings provide new insights into the mechanisms of the SARS-CoV-2 life cycle and identify a potential target for developing treatments for the virus-related diseases.
Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis
Authors: Nahas Kamal L , Connor Viv , Wijesinghe Kaveesha J , Barrow Henry G , Dobbie Ian M , Harkiolaki Maria , Graham Stephen C , Crump Colin M
Published: February 2025

Numerous viral genes are involved in assembly of herpes simplex virus-1 (HSV-1), but their relative importance and function remain poorly characterised. Transmission electron microscopy has been used to study viral protein function in cells infected with HSV-1 mutants; however, these studies were usually conducted without correlative light microscopy to identify specific viral components. In this study, fluorescent capsid (eYFP-VP26) and envelope (gM-mCherry) proteins were imaged by structured illumination microscopy under cryogenic conditions (cryoSIM) and cellular ultrastructure was captured from the same infected cells using cryo-soft-X-ray tomography (cryoSXT). Nine fluorescent HSV-1 mutants, each lacking a different viral protein, were compared to assess the importance of viral proteins in different stages of HSV-1 morphogenesis. The relative importance of five viral proteins to nuclear egress were ranked (pUL34 > pUL21 > VP16 > pUL16 > pUS3) according to the levels of attenuation observed for each virus. Correlative imaging also revealed the roles of five viral proteins in cytoplasmic envelopment. VP16 was found to be important in capsid delivery to envelopment compartments, while cytoplasmic clusters of virus particles plus features of stalled envelopment not previously described were observed in the absence of pUL11, pUL51, gK, and gE. Finally, this 3D imaging approach was used to capture different assembly stages during cytoplasmic envelopment and to determine that envelopment occurs by particle budding rather than wrapping. The findings demonstrate that tomographic 3D correlative imaging is an emerging technology that sheds new light on viral protein functions and virion morphogenesis.
Precision-based causal inference modulates audiovisual temporal recalibration
Authors: Li Luhe , Hong Fangfang , Badde Stephanie , Landy Michael S
Published: February 2025

Cross-modal temporal recalibration guarantees stable temporal perception across ever-changing environments. Yet, the mechanisms of cross-modal temporal recalibration remain unknown. Here, we conducted an experiment to measure how participants’ temporal perception was affected by exposure to audiovisual stimuli with constant temporal delays that we varied across sessions. Consistent with previous findings, recalibration effects plateaued with increasing audiovisual asynchrony (nonlinearity) and varied by which modality led during the exposure phase (asymmetry). We compared six observer models that differed in how they update the audiovisual temporal bias during the exposure phase and in whether they assume a modality-specific or modality-independent precision of arrival latency. The causal-inference observer shifts the audiovisual temporal bias to compensate for perceived asynchrony, which is inferred by considering two causal scenarios: when the audiovisual stimuli have a common cause or separate causes. The asynchrony-contingent observer updates the bias to achieve simultaneity of auditory and visual measurements, modulating the update rate by the likelihood of the audiovisual stimuli originating from a simultaneous event. In the asynchrony-correction model, the observer first assesses whether the sensory measurement is asynchronous; if so, she adjusts the bias proportionally to the magnitude of the measured asynchrony. Each model was paired with either modality-specific or modality-independent precision of arrival latency. A Bayesian model comparison revealed that both the causal-inference process and modality-specific precision in arrival latency are required to capture the nonlinearity and asymmetry observed in audiovisual temporal recalibration. Our findings support the hypothesis that audiovisual temporal recalibration relies on the same causal-inference processes that govern cross-modal perception.
An explainable multi-objective hybrid machine learning model for reducing heart failure mortality
Authors: Shamrat F M Javed Mehedi , Khalid Majdi , Qadah Thamir M. , Farrash Majed , Alshanbari Hanan
Published: February 2025

As the world grapples with pandemics and increasing stress levels among individuals, heart failure (HF) has emerged as a prominent cause of mortality on a global scale. The most effective approach to improving the chances of individuals’ survival is to diagnose this condition at an early stage. Researchers widely utilize supervised feature selection techniques alongside conventional standalone machine learning (ML) algorithms to achieve the goal. However, these approaches may not consistently demonstrate robust performance when applied to data that they have not encountered before, and struggle to discern intricate patterns within the data. Hence, we present a Multi-objective Stacked Enable Hybrid Model (MO-SEHM), that aims to find out the best feature subsets out of numerous different sets, considering multiple objectives. The Stacked Enable Hybrid Model (SEHM) plays the role of classifier and integrates with a multi-objective feature selection method, the Non-dominated Sorting Genetic Algorithm II (NSGA-II). We employed an HF dataset from the Faisalabad Institute of Cardiology (FIOC) and evaluated six ML models, including SEHM with and without NSGA-II for experimental purposes. The Pareto front (PF) demonstrates that our introduced MO-SEHM surpasses the other models, obtaining 94.87% accuracy with the nine relevant features. Finally, we have applied Local Interpretable Model-agnostic Explanations (LIME) with MO-SEHM to explain the reasons for individual outcomes, which makes our model transparent to the patients and stakeholders.
Analysis of biopsies of gastric cancer, intestinal and diffuse, and non-atrophic gastritis: an overview of loss of heterozygosity in Mexican patients
Authors: Larios-Serrato Violeta , Valdez-Salazar Hilda A. , Torres Javier , Camorlinga Margarita , Piña-Sánchez Patricia , Minauro Fernando , Ruiz-Tachiquín Martha-Eugenia
Published: February 2025

This study analyzed the loss of heterozygosity (LOH) effect on gastric cancer (GC) tumor samples from 21 Mexican patients, including diffuse (DGC) and intestinal (IGC) subtypes, as well as non-atrophic gastritis (NAG, control). Whole-genome high-density arrays were performed, and LOH regions were identified among the tissue samples. The differences in affected chromosomes were established among groups, with chromosomes 6 and 8 primarily affected in DGC and chromosomes 3, 16, and 17 in IGC. Functional pathway analysis revealed involvement in cancer-associated processes, such as signal transduction, immune response, and cellular metabolism. Five LOH-genes (IRAK1, IKBKG, PAK3, TKTL1, PRPS1) shared between GC and NAG suggest an early role in carcinogenesis. Specific genes were highlighted for Hallmarks of Cancer NAG-related genes (PTPRJ and NDUFS) were linked to cell proliferation and growth; IGC genes (GNAI2, RHOA, MAPKAPK3, MST1R) to genomic instability, metastasis, and arrest of cell death; and DGC genes to energy metabolism and immune evasion. These findings emphasize the role of LOH in GC pathogenesis and underscore the need for further research to understand LOH-affected genes and their diagnostic or evolution potential in cancer management. Portions of this text were previously published as part of a preprint (https://www.medrxiv.org/content/10.1101/2024.07.29.24311063v1).
Volatilidade dos preços das commodities minerais: minério de ferro
Authors: Oliveira Cristiane Sousa de , Silva Gerson Ferreira da , Souza Érika Márcia Assis de , Sousa Jacqueline de Lemos Coelho , Resende Sara Isabel de Melo , Diniz Hélio Augusto Goulart
Published: February 2025

O presente artigo analisa a volatilidade dos preços das commodities minerais, com foco no minério de ferro, e investiga como a influência da China no mercado global afeta essa volatilidade. A pesquisa foi conduzida por meio de uma por uma revisão bibliográfica abrangente e levantamento com funcionários de grandes empresas de minério de ferro. O levantamento visou identificar a percepção dos profissionais sobre as flutuações de preços e as estratégias adotadas por suas empresas para gerenciar os desafios decorrentes dessa volatilidade. Os resultados indicam uma conscientização significativa entre os funcionários em relação às variações de preços e revelam práticas diversificadas de gestão de risco nas empresas, como o uso de contratos futuros e estratégias de hedge. Concluiu-se que a volatilidade dos preços continua sendo um desafio crítico para a indústria, intensificado pela dinâmica da demanda chinesa.
Evaluation of the Shear Bond Strength of Orthodontic Adhesive Incorporated with Titanium Dioxide Nanoparticle: An In-vitro Study
Authors: Ahmed M Ashfaq , Sumalatha S , Narendran N , Nandakumar G Dinesh , Agasthiya A
Published: February 2025

Introduction: White Spot Lesions (WSL) are a common problem in orthodontic treatment due to improper oral hygiene maintenance and plaque accumulation, which reduce the bond strength of the appliance. To address this issue, various bonding materials have been introduced over time to enhance the bond strength of adhesives. Recently, different kinds of nanoparticles have been added to composite resins with the goal of enhancing bonding efficiency without affecting bond strength.

Aim: To evaluate the shear bond strength of Titanium Dioxide (TiO2 ) nanoparticle-incorporated orthodontic adhesive.

Materials and Methods: The present in-vitro study was conducted in the Department of Orthodontics and Dentofacial Orthopaedics, Best Dental Science College, Madurai, Tamil Nadu, India, between July 2022 and December 2023. Study included 60 samples of extracted human maxillary first premolar teeth. The samples were equally divided into two groups. In group 1, brackets were bonded with conventional composite, and in group 2, brackets were bonded with TiO2 nanocomposite. The shear bond strength for each group was determined using a universal testing machine, and Adhesive Remnant Index (ARI) scores were also assessed. Statistical analysis was conducted using the Student t-test and Chi-square test to evaluate the differences between the groups.

Results: The results of the study showed that the bond strength was significantly higher for the TiO2 nanocomposite group with mean±Standard Deviation (SD) of 14.3±1.21 MPa than for the conventional composite group with mean±SD of 12.9±1.05 MPa. This indicates that the TiO2 nanocomposite had significantly better bond strength than the conventional composite by 1.4 MPa (p-value=0.045). However, the ARI scores between the two groups were statistically not significant (p-value=0.682).

Conclusion: In conclusion, incorporating TiO2 into the conventional composite significantly enhanced the bond strength of the composite.
Comparison of force-time characteristics of prone cervicothoracic spinal manipulative therapy between chiropractic interns and chiropractors: A cross-sectional study
Authors: Perron François , Funabashi Martha , Gauthier Jean-Luc , Pagé Isabelle
Published: February 2025

Objective

Although the force-time characteristics of spinal manipulative therapy (SMT) have been extensively studied, evidence on the maturation of SMT delivered to the cervicothoracic junction is scarce. The aim of this study is to compare the force-time characteristics of a cervicothoracic SMT technique between experienced chiropractors and chiropractic interns. 

Methods

Participants performed a total of 18 posterior-to-anterior cervicothoracic SMT on a human-shaped manikin, fixed to an instrumented treatment table. Participants were instructed to execute the technique, contacting either the right or the left side of the manikin, at 3 different levels of force: low, typical, and high. Three-level analysis of variance was used to assess the effect of group (experienced chiropractors or interns), force level, and contact side on force-time characteristics. Variability of these characteristics among participants was also evaluated.

Results

No statistically significant differences were observed in any of the force-time characteristics between chiropractic interns (n = 15) and experienced chiropractors (n = 10), nor on the contact side used to perform the SMT (p > .05). Significant effects on force level were noted for all force-time characteristics (p < .05), except for impulse duration (p > .05). The interns displayed more variability than experienced chiropractors for the force at thrust initiation only (p = .02). 

Conclusion

This study shows that both chiropractic interns and experienced clinicians deliver SMT to the cervicothoracic junction with similar force-time characteristics. However, final-year students exhibited greater variability in controlling their force just before initiating the thrust, indicating that some aspects of their motor skill may still be developing.
Factors Influencing the Final Exam Scores of Students in the Pilot Course of Ecological Civilization Education at Kaili University, China
Authors: Luo Zukui , Shao Xianhui , Si Shengli , Meng Lixia
Published: February 2025

To enhance people's awareness of ecological civilization and to popularize the concept, the Ecological Civilization Education course was piloted with students of different levels in Guizhou Province, China, in 2020. As the only university representative of the pilot institute, Kaili University has been offering the Ecological Civilization Education course to all first-year students every autumn semester since 2020. However, we do not know which factors have impacts on teaching effectiveness in this course and to what extent they influence teaching effectiveness. We randomly selected 60 classes at Kaili University from 2020 to 2023 and collected data from all the students of these classes for this study, and we analyzed 10 factors that may affect the final exam score in the course. The generalized linear model showed that there were differences in scores between genders, among students' majors, and between years of enrollment. Class size, the mean score on homework, and the attention rate had significant positive impacts on the final exam score. Students' participation and completed assignments did not have significant impacts. However, the percentage of completed assignments had a significant negative impact. The results indicate that assigning too much homework was detrimental to final exam score. Although our findings are based on a local sample, they have guiding significance for the future implementation of this course throughout China.
A Comprehensive Review on Edible Flowers: The Sustainable Solution for Food Security and Nutrition
Authors: Santhoshini C N R , Jagadeeswari V.V. , Makwana Rushabh J. , Pradhan Rahul , Burdak Manoj Kumar , Mahesh Padi , Nagaraju Vankadavath , Krushnaji Rathod Tushar
Published: February 2025

As the global population continues to grow, ensuring food security and proper nutrition has become more challenging than ever. Edible flowers, once primarily valued for their beauty and cultural significance, are now gaining attention as a sustainable and nutritious food source. Packed with essential vitamins, minerals, and antioxidants, these flowers offer potential health benefits, such as anti-inflammatory and antimicrobial properties. Their ability to thrive with minimal resources makes them an environmentally friendly addition to modern food systems.
This review explores the historical and cultural significance of edible flowers, their nutritional and health benefits, and their role in promoting sustainable agriculture. We also discuss their growing presence in culinary and commercial applications, from salads and teas to functional food products. However, despite their potential, challenges like limited consumer awareness, concerns about food safety, and short shelf life remain barriers to widespread adoption. Addressing these issues through research, policy support, and education could unlock the full potential of edible flowers in enhancing global food security. By integrating these nutrient-rich blooms into daily diets, we can take a step toward a healthier, more sustainable future.
Multidisciplinary Surgical Management of Coexisting Frontoethmoidal Mucocele and Meningioma: A Case Report
Authors: Cordeiro João Francisco Barbosa , Vanolli Rafael da Silva , Oliveira Gabriela Cavalieri de , Souza Bruna Caroline Ruthes de , Schmidt Paulo Ricardo Correa , Conci Ricardo Augusto , Júnior Eleonor Álvaro Garbin , Griza Geraldo Luiz , Santos Marcius Benigno Marques dos
Published: February 2025

Aims: This study aims to review the multidisciplinary surgical approach to managing frontal sinus mucoceles associated with meningiomas, emphasizing the importance of collaboration between maxillofacial surgery and neurosurgery. The objective is to assess optimal strategies for lesion removal, sinus reconstruction, and postoperative care to reduce complications and improve patient outcomes.
Study Design: This is a retrospective literature review analyzing documented cases of coexisting frontal sinus mucoceles and meningiomas, along with their surgical management and outcomes.
Place and Duration of Study: Relevant studies from multiple medical institutions and surgical case reports published in peer-reviewed journals between 1979 and 2024 were included.
Methodology: Data were collected from published case studies and reviews on patients diagnosed with both frontal sinus mucoceles and meningiomas. The analysis focused on surgical techniques, the involvement of different medical specialties, and postoperative results. Special attention was given to procedures such as frontal sinus cranialization, sinus drainage restoration, and prevention of mucocele recurrence.
Results: The coexistence of frontal sinus mucoceles and meningiomas presents significant surgical challenges, requiring a coordinated effort between maxillofacial and neurosurgical teams. Studies indicate that the obstruction of the frontal sinus ostium by a meningioma often predisposes patients to secondary mucocele formation. Advanced reconstruction techniques, such as cranialization and frontal recess obliteration, significantly reduce recurrence rates and postoperative complications. The integration of endoscopic and open surgical approaches has demonstrated favorable outcomes, minimizing morbidity and enhancing functional recovery.
Conclusion: A multidisciplinary surgical approach is essential for successfully managing frontal sinus mucoceles associated with meningiomas. Proper lesion removal, sinus reconstruction, and long-term follow-up can prevent recurrence and ensure optimal patient outcomes. Further research and case studies are needed to refine treatment strategies and improve surgical planning in these complex cases. Decrease medical as well as financial burden, hence improving the management of cirrhotic patients. These predictors, however, need further work to validate reliability.
The Role of Aromatherapy in the Management of Dental Anxiety in Paediatric Patients: A Narrative Review
Authors: Santos Henrique Costa dos , Muniz Millena Fernandes Silva , Melo Callebe Carneiro de , Magalhães Amanda Neves , Alcântara Lívia Fialho
Published: February 2025

Aims: The aim of this study is to carry out a narrative review of the use of aromatherapy in the management of paediatric dental patients, analyzing its advantages, benefits and applicability in relation to dental anxiety, since this practice is low-cost, accessible and has minimal adverse effects.
Study Design: The study consists of a narrative review through an electronic search of evaluated and unevaluated clinical trials that evaluated aromatherapy as a mechanism for reducing anxiety during pediatric dental care, compared to control (no aromatherapy), other positive control approaches (such as music, games, audiovisual distraction) or pharmacological approaches. Clinical trials were searched in the SciELO, PubMed and Virtual Health Library (BVS) databases, using the descriptors Aromatherapy AND Pediatric Dentistry, published between 2018 and 2025, which were available in full text format, without predicting the language of publication, without country restrictions and within the researched theme. Studies that did not meet the inclusion criteria were excluded.
Results: The electronic search found 11 studies available in the literature. After reading the titles and abstracts, 04 studies were excluded that did not meet the pre-established inclusion criteria or that did not meet the objective of this review. Therefore, 07 clinical trials were read in full and added to the literature base that supported this study. This evidence shows the benefits of aromatherapy as a complementary alternative in the treatment of pediatric dentistry patients and presents overwhelming results in the management of anxiety and patient behavior.
Conclusion: Aromatherapy is an important alternative in managing anxiety in pediatric dentistry patients, being safe, of good applicability and low cost. It is suggested that new robust studies be developed that further emphasize the technique, aiming at the benefits of the practice.
Bioengineered Versatile Heterojunctions as Stress Busters Targeting Matrix Degradation and Ferroptosis for Osteoarthritis Therapy
Authors: Zhang Zhao , Cheng Debin , Liu Dong , Dang Jingyi , Wang Xiaohe , Wu Hong , Fan Hongbin
Published: January 2025

Osteoarthritis (OA) is a chronic joint disease characterized by degeneration of articular cartilage, with the underlying mechanism being the inability of chondrocytes to maintain homeostasis in response to the changing stress. The stress response triggered by excess ROS from various factors is critical in regulating chondrocyte survival and fate. In this study, 2D Mo4/3B2‐X MBene and cerium‐gallic acid metal‐polyphenol network (MPN) together with cartilage‐targeted shell of hyaluronic acid and WYRGRL (HW) are utilized to development bio‐heterojunction MBene@MPN‐HW (MBM‐HW) through self‐assembly. The bio‐heterojunction MBM‐HW not only demonstrates superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) enzyme mimicking capabilities to effectively scavenge excess ROS, but also exhibits dual‐responsive release and cartilage‐targeting properties. Importantly, both in vivo and in vitro experiments indicate that MBM‐HW could alleviate chondrocyte oxidative stress, protect mitochondrial function, suppress cartilage matrix degeneration and ferroptosis, thereby slowing the progression of OA. Mechanistically, it is demonstrated that MBM‐HW could attenuate Perk/eIF2α cascade mediated integrated stress response to effectively restrain matrix degeneration and ferroptosis, thereby maintaining chondrocyte homeostasis. Overall, this work underscores the robust stress‐relieving capacity of bio‐heterojunction MBM‐HW, providing a novel approach for the treatment of OA.
Atmospheric Pressure Dried Discontinuous Pore Gradient Structured CNF‐Based Aerogel for Ultra‐Low Reflection, Broadband, and Super‐High EMI Shielding
Authors: Mao Yunshan , Sheng Yuhao , Fan Zheyu , Yang Jing , Liu Jian , Tang Chunxia , Fu Shaohai
Published: January 2025

Large scale production of aerogels with ultra‐low reflection coefficients for electromagnetic interference (EMI) shielding remains a significant challenge. This work reports a gradient and large area composite nanocellulose fiber aerogel (CNA) with discontinuous pores structures using ice crystal dissolution/regeneration and atmospheric pressure drying strategies. The CNA consisting of three layers of ordered‐ordered‐disordered pore orientation achieved ultra‐high EMI shielding efficiency (>90 dB) across ultra‐broad electromagnetic wave (EMW) bands (L, S, C, X, Ku‐band) and exhibited ultra‐low reflection coefficient (R ≈ 0.20). Simulation results confirmed that the average pore sizes of layers 1 and 2 should be 120 and 40 µm for achieving excellent EMW transmission and absorption, respectively. The disordered pore structure of layer 3 with an average size of less than 345 µm showed significant characteristics in reflecting EMW and is unaffected by the material dielectric properties. Furthermore, the CNA demonstrated great potential in selective recovery of ethanol waste produced from the aerogel preparation process. It showed an evaporation rate of 3.3 Kg m−2 h at 1.0 sun and yielded a concentration of up to 96.1% in a natural environment. This study provides new insights and approaches for the pore structure design of aerogels in EMI shielding.
CO2 Chemical Trap and Electronegative Microenvironment Enable Metal–Organic Framework with One‐Step Ethylene Purification from Quaternary Mixture
Authors: Zheng Mingze , Fang Zhi , Xue Wenjuan , Yan Tongan , Huang Hongliang , Zhong Chongli
Published: January 2025

One‐step purification of C2H4 from a four‐component CO2/C2H6/C2H2/C2H4 mixture with a single adsorbent is of great significance but very challenging. Herein a feasible and general strategy is reported for constructing chemical traps in MOF featuring an electronegative microenvironment in the pore wall for one‐step purification of C2H4 from the four‐component mixture. The enzyme‐mimicking Zn‐OH sites in CFA‐Zn‐OH, acting as a CO2 chemical trap, can efficiently fix CO2 while the electronegative pore wall in MOF ensures the preferential adsorption of C2H2 and C2H6 impurities, thus leading to the one‐step purification of C2H4 from a four‐component mixture. Mechanism studies reveal that the Zn‐OH sites in CFA‐Zn‐OH can chemically fix CO2 impurity in a reversible manner to form bicarbonate Zn‐HCO3, mimicking the carbonic anhydrase. In addition, the negative electrostatic potential of the pore wall allows CFA‐Zn‐OH to preferentially capture C2H2, and C2H6 impurities, thus ensuring one‐step C2H4 purification from the four‐component mixture. Column breakthrough experiments validated its ability for one‐step C2H4 purification on from the four‐component mixture and C2H4 with a purity of 99.9% can be directly harvested.
Mitochondria‐targeting Bimetallic Cluster Nanozymes Alleviate Neuropathic Pain Through Scavenging ROS and Reducing Inflammation
Authors: Cheng Xiaolei , Xia Tianjiao , Han Min , Xu Minhui , Yuan Weining , Wei Ziqi , Jiang Wei , Tang Hao , Bai Qian , Gu Xiaoping
Published: January 2025

Neuropathic pain is a significant public health concern. Inflammatory mediators and reactive oxygen species (ROS) are recognized as primary contributors to pain perception. In this study, a mitochondria‐targeted modification of bimetallic cluster nanozyme (TPP‐Au‐Ru) is developed. This TPP‐Au‐Ru nanozyme exhibits a high affinity for the mitochondrial matrix, effectively scavenging ROS and attenuating inflammatory mediators in both in vitro and in vivo settings. Additionally, the nanozyme inhibits the activation of the MAPK and NF‐κB signaling cascades and protect mitochondrial function. Furthermore, a therapeutic dose of the TPP‐Au‐Ru nanozyme is able to alleviate nociceptive symptoms for up to 36 h with minimal biological toxicity. Therefore, the sustained mitochondrial delivery of TPP‐Au‐Ru nanozyme provides an effective and long‐lasting approach to neuropathic pain. This innovative approach shows promise for the development of more efficient therapeutic interventions, potentially revolutionizing the management of neuropathic pain and enhancing the quality of life for affected individuals.
From Printed Devices to Vertically Stacked, 3D Flexible Hybrid Systems
Authors: Liu Fengyuan , Christou Adamos , Dahiya Abhishek Singh , Dahiya Ravinder
Published: January 2025

The pursuit of miniaturized Si electronics has revolutionized computing and communication. During recent years, the value addition in electronics has also been achieved through printing, flexible and stretchable electronics form factors, and integration over areas larger than wafer size. Unlike Si semiconductor manufacturing which takes months from tape‐out to wafer production, printed electronics offers greater flexibility and fast‐prototyping capabilities with lesser resources and waste generation. While significant advances have been made with various types of printed sensors and other passive devices, printed circuits still lag behind Si‐based electronics in terms of performance, integration density, and functionality. In this regard, recent advances using high‐resolution printing coupled with the use of high mobility materials and device engineering, for both in‐plane and out‐of‐plane integration, raise hopes. This paper focuses on the progress in printed electronics, highlighting emerging printing technologies and related aspects such as resource efficiency, environmental impact, integration scale, and the novel functionalities enabled by vertical integration of printed electronics. By highlighting these advances, this paper intends to reveal the future promise of printed electronics as a sustainable and resource‐efficient route for realizing high‐performance integrated circuits and systems.
Self‐Adaptive Polarized Photoresponse in Organic Single‐Crystal Phototransistors for Bionic Night‐Time Polarization Perception
Authors: Pan Jing , Chen Shuai , Chen Shuang , Wang Jinwen , Su Mingming , Jia Ruofei , Jie Jiansheng , Zhang Xiujuan
Published: January 2025

The emerging semiconductor micro/nanocrystals with intrinsic anisotropy have provided new perspectives for low‐cost and simplified polarimetry. However, the low polarization sensitivity of state‐of‐the‐art polarimeters based on anisotropic semiconductors under weak and partially polarized light severely hinders their practical application in complex dim environments. Here, a photo‐adaptive polarization‐sensitive organic phototransistor (POL‐OPT) is demonstrated for bionic weak‐light polarization perception. The combination of highly anisotropic organic crystals with charge‐storage accumulative effect enables a self‐adaptive polarized photoresponse of the phototransistor to imitate the bionic scotopic adaptation process. Consequently, an ultrahigh dichroic ratio (DR) of over 105 is achieved through time accumulation under an ultraweak light intensity of 200 nW cm−2, which is among the highest in polarization‐sensitive photodetectors. Furthermore, POL‐OPT array is constructed for effective polarization perception in an artificial moonlit environment with a low degree of linear polarization (DoLP) down to 0.26, reaching the detection threshold of night‐active dung beetles. This study offers a new opportunity for the development of new‐generation high‐performance polarimeters for polarization imaging, bionic navigation, and artificial visual systems.
Colloidal Quantum‐Dot Heterojunction Imagers for Room‐Temperature Thermal Imaging
Authors: Mu Ge , Zheng Xiaolong , Tan Yimei , Liu Yanfei , Hao Qun , Weng Kangkang , Tang Xin
Published: January 2025

Room‐temperature operation or high‐operation temperature (HOT) is essential for mid‐wave infrared (MWIR) optoelectronics devices providing low‐cost and compact systems for numerous applications. Colloidal quantum dots (CQDs) have emerged as a rising candidate to enable photodetectors to operate at HOT or room temperature and develop the next‐generation infrared focal plane array (FPA) imagers. Here, band‐engineered heterojunctions are demonstrated to suppress dark current with well‐passivated mercury telluride (HgTe) CQDs enabling room‐temperature MWIR imaging by single‐pixel scanning and 640 × 512 FPA sensitive thermal imaging above 250 K. As a result, the room‐temperature detectivity reaches as high as 1.26 × 1010 Jones, and the noise equivalent temperature difference (NETD) is as good as 25 mK up to 200 K.