bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of telephone and SMS Follow-up on quality of life and fatigue in patients with chronic obstructive pulmonary disease: A three-month RCT-follow-up study
Authors: Fathizadeh Dehkordi Parisa , Heidari Haydeh , Masoudi Reza , Sedehi Morteza , Khajeali Fereydoon
Published: October 2024

Background and aims: To compare the effect of telephone and SMS follow-up of an empowerment program on quality of life (QOL) and fatigue in patients with chronic obstructive pulmonary disease (COPD). Methods: Non-blind randomized clinical trial (RCT). Two hospitals and clinics in Shahrekord. 105 patients with COPD grades 2 and 3 were recruited and, after implementation in empowerment sessions, were randomly assigned to three control, telephone follow-up, and SMS follow-up groups (35 individuals in each group). First, the pulmonary empowerment program was designed and implemented for six 90-minute sessions. Then, the patients were randomly assigned to three groups using a random number table. Follow-up ended after three months, and the control group received routine care. Data were collected in the first and sixth sessions of the empowerment program and at the end of the follow-up period using demographic (QOL) and fatigue questionnaires. Eventually, they were analyzed through correlation coefficient and analysis of variance (ANOVA) tests in the SPSS software (Version 20). Results: The study results on QOL showed that the groups were not statistically significantly different before and after the empowerment (respectively: P=0.29 and P=0.56). However, the groups showed statistically significant differences at the end of the quarterly follow-up period (P<0.001). ANOVA results for fatigue indicated no statistically significant differences between the groups before and after the empowerment (respectively: P=0.10 and P=0.32). The results of this study showed that follow-up by SMS and telephone improved patients’ QOL, and SMS had a greater effect in this regard. Conclusion: The findings suggest using follow-up as an essential approach to empowerment using various technology methods and designing more comprehensive empowerment to reduce patient fatigue.
Ureteroneocistostomia unilateral em cadela com neoplasia em região intra-abdominal e comprometimento ureteral
Authors: Mendonça Hugo Leite Serrano de , Aleixo Grazielle Anahy de Souza , Martir Ediclesio Andrade , Guimarães Evelen da Silva , Lima Déborah Cavalcante de Aliança , Lima Maynara Kayla Ferreira , Siqueira Filho Robério Silveira de , Souza Wandsson João da Silva e
Published: October 2024

A ureteroneocistostomia é uma técnica cirúrgica utilizada para preservar o rim em casos onde o ureter está comprometido, geralmente devido a neoplasias intra-abdominais ou quaisquer outros fatores que causam obstrução. A técnica consiste na implantação do ureter na bexiga, evitando a necessidade de nefrectomia, e é recomendada em situações onde o rim ainda apresenta função. O presente trabalho relata um caso de ureteroneocistostomia em uma cadela de 11 anos, sem raça definida, atendida no Hospital Veterinário Universitário da Universidade Federal Rural de Pernambuco (UFRPE), com histórico de massa intra-abdominal comprometendo o ureter direito, resultando em hidronefrose e ureteronefrose. Após exames de imagem, foi indicada a cirurgia, submetendo a ressecção parcial da massa e a ureteroneocistostomia, com inserção de sonda uretral até o terço médio do ureter para prevenir estenose. A paciente foi mantida sob cuidados intensivos por cinco dias e, após 15 dias da cirurgia, veio a óbito, possivelmente devido a complicações pós-cirúrgica. Conclui-se que a ureteroneocistostomia é eficaz para preservar o rim em casos de obstrução ureteral, mas o sucesso do procedimento depende do nível de comprometimento das estruturas adjacentes, assim como o tipo e o grau da neoplasia.
Characterization of Prickly Pear plantations in semi-arid zones! A green revolution in East Algeria: Case of the Tébessa region
Authors: Mourad Douh , Larbi Karkour , Chekchaki Samir , Boumzaouet Alaoua , Samia Rebai , Bouchaala Laid
Published: October 2024

The study carried out on the prickly pear shrub, in three potential production sites belonging to the commune of Ain Zerga district of Tébessa in the extreme east of the Algerian arid zone. The aim of this study was to try to interpret the main characteristics and sources of variability of this shrub of multiple interests. Carried out in 2023 on orchards planted with adult Opuntia ficus indica, developed in 45 orchards divided into 15 per site located in three localities, namely Henchir Lahdid, El Guefaifia, and Ouled Mebarek. The trees are grown extensively, with production starting in the last week of May. The cactus shrub reaches an equivalent production (10.23) kg and a production of 11,137.65kg/ha. At the time of the commercial harvest, indicated by the change in skin color, we carried out a random collection of 05 fruits per orchard, i.e. 75 fruits per site (225 fruits); these fruits were evaluated by various measurements. Shrub-specific variables such as fruit position in the canopy, cladode length, width, density, and inter-line spacing, number and weight of fruits per tree and per cladode, and annual productivity were studied. These variables per cactus shrub and fruit changed significantly as a function of climatic and edaphic environmental conditions, i.e. site and altitude, while the number of seeds/fruits was conditioned by volume. Fruit weight varied greatly within the same tree, influenced by the number of fruits per tree and the surface area of the cladodes; this variability decreased for cladodes bearing more than six fruits. Interception of climatic conditions (light) and cladode dry weight were the sources of variability in fruit weight, whereas Opuntia plant/hectare density had no effect on fruit quality.
Perfil do consumidor de carne ovina no município de Mossoró - Rio Grande do Norte
Authors: Paiva Ruana Rafaela Lira Torquato , Torquato Raquel Rayanne Silva , Silva Juliane Nayra Dantas , Teófilo Tiago da Silva , Santos Gleyson Araújo dos , Moreira Rennan Herculano Rufino , Cordeiro Ana Rita Ribeiro de Araújo , Sousa Kátia Regina
Published: October 2024

Compreender o comportamento do consumidor de carne ovina permite um entendimento assertivo das demandas e preferências do mercado. Este estudo visou caracterizar o perfil do consumidor de carne ovina no município de Mossoró, localizado no estado do Rio Grande do Norte. Para tanto foi utilizada uma metodologia de pesquisa do tipo Survey. A coleta de dados foi realizada através de um questionário online, contendo 35 questões fechadas, cobrindo aspectos sociodemográficos e de consumo. Os resultados mostraram que a maioria dos consumidores é do sexo feminino, adultos, com alta escolaridade e renda, residindo na zona rural, predominantemente ocupados no serviço público, trabalho autônomo, ou estudando. Na análise estatística, não foi observada uma influência significativa do gênero em relação a outros aspectos demográficos ou à frequência de consumo da carne ovina. Os principais motivadores de consumo foram o sabor característico da carne ovina, aspectos tradicionais e benefícios nutricionais. Os cortes mais consumidos incluem costela, pernil e coxão mole, geralmente preparados assados ou cozidos. Observou-se também uma demanda potencial por derivados, como linguiças e hambúrgueres, se estes estiverem disponíveis nos supermercados. Esses resultados são valiosos para produtores, varejistas e profissionais de marketing, auxiliando no desenvolvimento de estratégias para atender às preferências dos consumidores de carne ovina em Mossoró.
Влияние возраста первого отела на молочную продуктивность и качество молока
Authors: Вахрамова О.Г. , Бузина О.В. , Черемуха Е.Г. , Ревякин А.О. , Зеленина О.В.
Published: October 2024

Nowadays, in order to reduce the cost of replacement heifers raising, early insemination and, accordingly, earlier use of cows are practiced in many farms. The purpose of the research is to study the relationship between milk productivity and the age of the first insemination of Holstein heifers under the conditions of OOO Kaluzhskaya Niva (a limited liability company under the laws of Russian Federation) in the Peremyshl district. The experimental groups were formed from cows with completed fourth lactation, taking into account the age of the first fruitful insemination. As the result of the study, it was found out that the optimal insemination index is observed at heifers of the first and second groups upon reaching the age of 12-14 months with a live weight of 337.6-340.9 kg. The shortage of live weight of heifers by the age of 12 months lengthens the time of raising, and reduces the effectiveness of their insemination (group 4 – the multiplicity of insemination is 3.3). The maximum growth rate was observed at heifers of the first group and made 865-931 g/day, which is 6.1-32.1% higher than in heifers of the other groups. When analyzing the dairy productivity of cows, there is a tendency to decrease the level at the second and third lactations, and an increase in the fourth lactation in comparison with the first one. More balanced lactation activity in a number of lactations is observed in cows of the third group (II lactation decreased by 2%, III - decreased by 5%, IV – increased by 17.5%, compared with the first lactation). At the same time, the variation in milk yield in cows of the other groups ranges from -9.2% to +20.6%. The differences in the indicators of the mass fraction of fat and the mass fraction of protein in milk of cows of different groups are not significant. The tendency of decrease of the mass fraction of fat in milk in cows of all groups is noted by the 4th lactation, with increase in the mass fraction of protein. Thus, for the manifestation of high milk productivity and its preservation in a number of lactation, the optimal age for the first insemination of Holstein heifers is 15-16 months.
Исследование сыпучести зерновых материалов в условиях стесненности
Authors: Аммосов И.Н. , Ямпилов С.С. , Дондоков Ю.Ж. , Дринча В.М.
Published: October 2024

Определены физические значения термина угол естественного откоса (при свободном истечении материала из бункеров) и термина угол естественного откоса в состоянии покоя (при исходном статическом положении материала). Проанализированы свойства зерновых материалов, влияющие на их сыпучесть. Установлено, что угол естественного откоса при свободном истечении больше угла естественного откоса при статическом положении. Определены основные способы и аналитические зависимости определения сыпучести зерновых материалов в условиях свободного истечения из емкостей. Разработана лабораторная установка для определения свойств сыпучести зернового материала, находящегося в стесненных условиях (статической емкости). Представлены физические основы и основные положения определения сыпучести зерновых материалов в условиях стесненности. Из трех исследованных вариантов расположения перегородок наименьшее проникновение зерна между перегородок имеет место при их вертикальном положении, а наибольшее – при горизонтальном размещении, причем сравнение проводили при одинаковом расстоянии между перегородками. Получены уравнения регрессии, описывающие проникновение зернового материала в пространство, образованное параллельно расположенными пластинами в разработанной лабораторной установке. Уравнение регрессии может быть использовано для инженерного расчета конструктивных элементов машин и вспомогательного оборудования в области зернопроизводства.

The physical values of the angle of repose (with free flow of material from the bunkers) term and the term of angle of repose in a state of rest (with the initial static position of the material) were determined. The properties of grain materials affecting their flowability were analyzed. It was found out that the angle of repose with free flow is greater than the angle of repose in a static position. The main methods and analytical relationships for determining the flowability of grain materials under conditions of free flow from containers were defined. A laboratory unit was developed to determine the flowability properties of grain materials located in cramped conditions (static container). The physical foundations and basic principals for determining the flowability of grain mate-rials under the confined space were presented. Out of three studied options for the arrangement of partitions, the least penetration of grain between the partitions occured when they were vertically po-sitioned, and the greatest grain penetration - when placed horizontally, the comparison was made with the same distance between the partitions. Regression equation was obtained describing the penetration of grain materials into the space between parallel plates in a developed laboratory unit. The regression equation can be used for engineering calculations of structural elements of machines and auxiliary equipment in the field of grain production.
Очистка семенного зерна ячменя
Authors: Абидуев А.А. , Пехутов А.С. , Бадмацыренов Д.-Ц.Б. , Болоев П.А. , Кокиева Г.Е.
Published: October 2024

Семенной материал ячменя в хозяйствах Республики Бурятия имеет неудовлетворительное качество, в основном, по содержанию семян сорных и культурных растений, в частности пшеницы. Анализ размерных характеристик семян ячменя и пшеницы показывает, что мелкие семена пшеницы могут быть выделены из обрабатываемого материала на подсевном сите с продолговатыми отверстиями как мелкие примеси, а оставшиеся в нем семена данного засорителя могут быть выделены в зерноочистительной машине с ячеистым цилиндром как короткие примеси. Путем анализа нормальных распределений длины семян ячменя и пшеницы установлено, что при разделении зерновой смеси по максимальной длине последней обеспечивается высокое качество обработки. Разработана методика выбора размера ячеек цилиндра зерноочистительной машины для очистки семян ячменя от коротких примесей (пшеницы). Размер ячеек цилиндра рекомендуется выбрать 1,10 – 1,25-кратным максимальной длины коротких примесей. Для окончательной очистки семян от пшеницы в хозяйствах Республики Бурятия рекомендуется обработать их в зерноочистительной машине с ячеистым цилиндром с размером ячеек 8,5 мм. Теоретическими и экспериментальными исследованиями обоснована технология очистки семенного зерна ячменя от трудноотделимых примесей и методика выбора размера ячеек цилиндров

The barley seed material on the farms of the Republic of Buryatia is of unsatisfactory quality mainly due to the presence of seeds of weed and cultivated plants, in particularly the presence of wheat grains. Analysis of the size features of barley and wheat seeds showed that the smaller wheat seeds can be isolated from the sowing material on a pre-sowing sieve with oblong holes as small impurities, and the remained seeds of this weed can be isolated in a grain cleaning machine with a cellular cylinder as short impurities. After analyzing of the normal length distributions of barley and wheat seeds, it was found out that during separating the grain mixture according to the maximum length of the latter, the high quality of processing is ensured. A method of selecting sizes of the cylinder cells of a grain cleaning machine for cleaning barley seeds from short impurities (wheat) was developed. It is recommended to choose the size of the cylinder cells equaled to 1.10 – 1.25 times of the maximum length of short impurities. For the final cleaning barley seeds from the wheat grains on the farms of the Republic of Buryatia, it is recommended to process them in a grain cleaning machine with a cellular cylinder with a cell size of 8.5 mm. The technology of cleaning barley seed grains from hard-to-separate impurities and the method of choosing the size of the cylinder cells of a grain cleaning machine for cleaning barley seeds from short impurities (wheat) were proved by the theoretical and experimental studies.
Spatiotemporal Trends in Human Immunodeficiency Virus Epidemics in Nigeria: A Systematic Review Protocol
Authors: Ayebaghobiobarakuma Flora Atiegha , Etokidem Prof. Ani , Maduka Prof. Omosivie
Published: October 2024

The scourge of the Human Immunodeficiency Virus infection is not abating fast as expected despite the many strategies put in place by various stakeholders. Geographical variations in its distribution have been implicated in its slow decline in sub-Saharan Africa, and Nigeria carries the highest burden in West Africa with subnational variations in 2019. This may negatively impact the implementation of interventions if not properly targeted. Geospatial technique is very important for spatial identification of hotspots and clusters which makes it easy to implement strategies, allocate scares resources, interventions and programs to achieve a success in the fight against the epidemics. It is on this note that the researcher is set to conduct this systematic review to assess trends in human immunodeficiency virus epidemics in Nigeria. The protocol will follow the preferred reporting items for systematic review and meta-analysis (PRISMA-P) 2020 guideline. The protocol was registered with the International Prospective Register for Systematic Reviews (PROSPERO) with registration number CRD42023488081. Articles would be retrieved electronically through database such as PubMed, Medline, Scopus, web of Science citation index, Google Scholar, and the open grey. Search period would be December 15th 2023 to June 15th, 2024 for related published articles. Two researchers will independently review articles for inclusion and if there are any disagreements, a third researcher would be called. Risk of bias would be assessed using New Castle Ottawa Scale and JBI critical appraisal checklist. Furthermore, statistical analysis will be conducted using the Review Manager Version 5.4. In conclusion, the Identification of clusters/hotspots helps the targeted allocation of scares resources, implementation of interventions and programs more efficiently and effectively. This strategy combined with the already existing ones, is a sure way to win the fight against the HIV epidemics.
Enucleation vs Marsupialization of dentigerous cysts in children
Authors: Chebrolu Reshma sri , Tetta Suma , Amudala Nikhila , Sandeep Kalisipudi , Anudeep Mupparapu , Sadik Mohammad Abdul , Sirisha Thsaliki Satya
Published: October 2024

Dentigerous cysts are common developmental odontogenic cysts found in the oral cavity. They are often discovered incidentally on dental X-rays or noticed as asymptomatic swellings. These cysts forms from reduced enamel epithelium that remains attached at the cementoenamel junction around the crown of an unerupted or impacted tooth. Although most dentigerous cysts are developmental, in young patients, they may also arise due to inflammation, often arising from decay in the primary teeth. Treatment options for dentigerous cysts range from marsupialization to complete removal, depending on the effect of the cyst on surrounding structures. The loss of a permanent tooth during the treatment of a dentigerous cyst can significantly impact a child's oral development. This article discusses 2 cases of primary teeth associated with cysts and their different treatment options.
LEADING-EDGE DEVELOPMENTS IN GUIDED ENDODONTICS: UTILIZING NEXT-GENERATION TOOLS
Authors: WADHAWAN RICHA , KUMARI CHANCHALA , BAIN POORVA , BANSAL DEEPAK , NGAIRANGBAM JAYALAKSHMI , KUMARI NEHA
Published: October 2024

Guided endodontics has revolutionized root canal therapy by integrating advanced technologies to improve precision, safety, and outcomes. This method combines imaging technologies like cone beam computed tomography (CBCT) with computer-assisted navigation systems to enhance the accuracy of root canal treatments. Key stages include initial diagnostic imaging, 3D virtual treatment planning, and the use of customized guides or templates during procedures. These guides help accurately identify canal orifices, reducing procedural errors and improving access to complex root structures. Benefits include better treatment predictability, reduced procedure time, and lower risk of complications. Recent advancements, such as high-resolution CBCT, advanced 3D printing for custom guides, and improved virtual planning, have enhanced the precision of access cavity preparations. Innovations like low-profile clinical templates address challenges with restricted mouth openings, while improved intraoral scanning and virtual planning streamline preparation processes. Despite higher costs and increased planning time, guided endodontics is increasingly seen as a standard method, offering substantial improvements in clinical practice and patient outcomes. This review consolidates these advancements, emphasizing their impact on precision, efficiency, and future research directions in endodontics.
Résultats de l’arthrodèse de la cheville selon la technique de MEARY. (À propos de 25 cas)
Authors: Ibrahim MARZOUKI , Ayoub Bouhmou , Kamal Lahrach , Amine Marzouki , Fawzi Boutayeb
Published: October 2024

La cheville est une articulation trochléenne, complexe subissant une force tridimensionnelle et des contraintes mécaniques énormes, sensible à la moindre anomalie anatomique. L’arthrodèse de la cheville demeure le traitement de choix dans les atteintes articulaires importantes de la cheville afin de lui restituer une indolence parfaite et une bonne stabilité. Les objectifs de notre étude sont de rechercher le profil épidémiologique et évaluer à long terme les résultats fonctionnels et le retentissement sur les articulations sous-talienne et médio tarsienne ainsi que sur la statique du pied. Cette étude rétrospective porte sur 25 cas d'arthrodèse de la cheville réalisée entre le 1er janvier 2013 et le 30 juin 2021 dans le service de traumatologie-orthopédie B3 du CHU HASSAN II à Fès. L'âge moyen des patients était de 38,4 ans (17-60 ans) et les femmes représentaient 64% des cas. La cheville droite a été opérée dans 80% des cas et la gauche dans 20% des cas. Les étiologies des atteintes étaient principalement dominées par les causes post-traumatiques (44%). Tous les patients ont subi une arthrodèse talocrurale par la technique de Meary. Deux cas d'infection du site opératoire ont été observés, mais ont été bien traités par une antibiothérapie adaptée. Huit patients ont présenté des douleurs résiduelles, un patient a présenté une pseudarthrodèse, trois patients ont développé une algodystrophie et trois patients ont souffert de troubles trophiques. Les résultats fonctionnels ont été évalués à l'aide du score AOFAS post-opératoire, qui était en moyenne de 72 points après un recul moyen de 4 ans. Le taux de fusion a été de 88%. Les résultats de cette étude sont comparables à ceux rapportés dans la littérature. En conclusion, l'arthrodèse de la cheville est une intervention utile pour restaurer la stabilité et l'indolence de la cheville, mais elle est délicate et nécessite une bonne orientation du pied dans les trois axes de l'espace ainsi qu'une bonne qualité de réalisation.
Fragment Reattachment of Maxillary Anterior Tooth- A Case Report
Authors: Gautam Dr. Prerna Sravan , Kumar M Dr. Praveen , M. S Dr. Prathap , Kini Dr. Shravan
Published: October 2024

Dental trauma often results in fracture of the tooth. Reattaching the fractured fragment is one among the treatment modalities in the management of fractured tooth. The procedure is simple and relatively inexpensive. However, understanding the limitations of the procedure is essential. Also, patient cooperation is essential for long term success of the treatment. The case report highlights the management of fractured maxillary anterior tooth in a elderly patient.
KAP study on hand hygiene in the era post COVID-19 SARS among general population.
Authors: Gupta Himani , Singh Bhanu Priya , Gupta Seema , Mahajan Vivek , Kreem Bhat Nusrat
Published: October 2024

Background: Hand hygiene accounts one of the most effective ways of keeping diseases at bay. As of now, this practice stands as a key cornerstone post COVID-19 era, thus helping to break the chain of contact transmission of such deadly outbreak’s outcome. Aims and Objectives: To assess knowledge, attitude and practices (KAP) relating to hand hygiene among general population post COVID-19 era. Materials and Methods: A cross-sectional study was done among general population of our setup over a span of 2 months by distributing online a pre-designed, pre-validated and semi-structured Google Form survey questionnaire having questions based on knowledge (10), attitude (07) and practices (06) relating to hand hygiene post COVID-19 era. Individuals enrolled were tech-savvy with access to e-mail and internet facility, and able to understand English language. Results: Data from responses of 545 individuals among our general community was collected and analyzed, out of which majority (88.9%) responders already had a basic insight about hand hygiene. 91.2% responders clearly believed hand hygiene is important to prevent the infection spread from contact. While 25.7% responders answered 40-60 seconds as minimum time required for hand washing, comparable majority (48.9%) marked it as 20-40 seconds. 70.9% responders were strongly against use of gloves as a substitute for hand washing. Interestingly, many had a mixed say regarding time span for which an alcohol-based hand sanitizer be rubbed onto hands viz. 32.3% stating it as 10 seconds, 27.7% as 20 seconds, 21.2% as 5 seconds and 18.8% as 15 seconds, respectively. Majority (85.4%) voted hand washing as better and probably the best mode of maintaining hand hygiene. Majority (93.1%) responders felt the need of practicing hand hygiene possibly at all the times. While most of our study population practiced hand hygiene thoroughly, 77.5% responders said that it positively affected their life also. However, in contrast, only 57.4% responders washed their hands after using public transport/money exchange, while 39.3% practiced it only sometimes. Conclusion: Our study highlights that despite of a positive relation between the awareness among general masses with regard to positive attitude about hand hygiene post COVID era, there was a mixed response about practice of the same, thus stressing on the need to reinforce such practices with due clarity so that the message goes loud and clear among public at large for breaking the chain of COVID transmission till date. Further our study can aid decision-makers in forecasting the effectiveness of infection mitigation strategies or in defining valid changes based on the practices, attitudes, and understanding of the intended population.
Amikacin Dosing Analysis in Sepsis Treatment: A Pharmacokinetic Study Based on Therapeutic Drug Monitoring
Authors: Sentat Triswanto , Lucida Henny , Widyati Widyati , Nasif Hansen , Harahap Yahdiana , Harijono Pandu , Ratih Ratih
Published: October 2024

Objectives: The primary purpose of this research was to evaluate the loading dose and maintenance dose of amikacin in the treatment of sepsis from intensive care unit (ICU) patients from May to July 2023 at the dr. Ramelan Naval Central Hospital in Indonesia. The analysis focus on the use of therapeutic drug monitoring (TDM) results to improve efficacy and safety of amikacin therapy. Material and Methods: A total of 8 sepsis patients received amikacin for 5 days. The loading dose was administered regardless of the renal function and was calculated of 7.5mg / kg body weight, administered intravenously as a bolus. The subsequent maintenance dose was delivered 4 hours following the loading dose at 15mg / kg body weight by an intermittent drip for 1 hour. The TDM measurement was conducted twice on the third day, with sampling conducted at 1.5 and 4 hours following the administration of the third amikacin maintenance dose. Results: The TDM results revealed that the amikacin t½ elpatients demonstrated Cpmax/MIC indices exceeding 8, while three patients exhibited AUC0-24h/MIC indices surpassing 75. The data showed variabilities in pharmacokinetic characteristics of amikacin in the sepsis patients due to comorbidities specifically patient’s creatinine clearance. Conlusion: The dose administered at efficacious doses attaining the desired PK/PD target while minimizing the risk of toxicity The findings of pharmacokinetic parameters on septis patient in Indonesia give valuable insights into the potential of amikacin therapy to enhance the possibility of achieving an effective treatment.
Cardiovascular Side Effects of COVID‑19 Vaccination
Authors: Vir Singh Malook
Published: October 2024

Background: The COVID-19 pandemic has had a profound impact on global health, with vaccination playing a crucial role in mitigating the spread of the virus and reducing the severity of illness. However, the potential cardiovascular side effects associated with COVID-19 vaccination have raised concerns. Myocarditis, an inflammation of the heart muscle, is one of the most widely reported side effects, particularly among male adolescents and young adults, following the second dose of mRNA vaccines. The incidence of myocarditis post-vaccination ranges from 150 to 4,000 cases per 100,000 individuals, higher than the pre-pandemic estimate of 1-10 cases per 100,000. Other cardiovascular complications such as pericarditis and stroke have also been reported in a small subset of vaccine recipients. Although these side effects are often acute and transient, they can be severe and even fatal in some cases. Understanding the incidence, clinical presentation, and long-term outcomes of these cardiovascular side effects is crucial for informing healthcare professionals and the public about the potential risks and benefits of the COVID-19 vaccination. Ongoing research and surveillance are essential to better understand the underlying mechanisms, identify risk factors, and develop strategies for preventing and managing adverse events, while maintaining public trust in the safety and efficacy of COVID-19 vaccines.Search Methods: This review was conducted by searching the WHO database and other relevant medical literature for studies published from 2000 to 2024 that reported on cardiovascular side effects of COVID-19 vaccination. Conclusion: Several studies have investigated the incidence of myocarditis, pericarditis, and stroke in individuals who received the COVID‑19 vaccines. Although the overall risk appears relatively low, cardiovascular complications have been reported in a small subset of vaccine recipients, particularly among younger individuals. These effects are often acute and transient but can be severe and even fatal in a few cases. Herein, we have provided a comprehensive review of documents reporting cardiovascular side effects of COVID-19 vaccines in international databases from 2000 to 2024 and discussed the possible causes of these disorders.
Enhancing Therapeutic Drug Monitoring in Indonesia: An Android-Based Pharmacokinetic Calculator for Amikacin
Authors: Sentat Triswanto , Lucida Henny , Widyati Widyati , Nasif Hansen
Published: October 2024

Pharmacokinetics employs complex mathematics to study, model, and predict how drugs are absorbed, distributed, metabolized, and excreted by the body. Amikacin, as a model drug with a narrow therapeutic window, requires Therapeutic Drug Monitoring (TDM) to ensure safety. This study developed an Android-based pharmacokinetic calculator, the "Indonesia Pharmacokinetic Calculator" (KFI), to assist clinical practitioners in quickly and accurately calculating pharmacokinetic parameters using patient weight and Amikacin doses as inputs. The application is designed to provide calculations of pharmacokinetic parameters, a pharmacokinetic simulation graph (plasma concentration-time curve), and predictions of individual patient amikacin plasma concentrations to assess therapeutic effectiveness and minimize toxicity risks. The rigorous testing process has demonstrated that KFI reliably produces expected output data, enhancing clinical pharmacy services in Indonesia through the integration of cutting-edge technology. This tool is expected to improve therapeutic outcomes, particularly for sepsis patients, by facilitating accurate and efficient pharmacokinetic calculations.
Study On The Efficacy Of Peronema Canescens Jack. Leaves As An Immunomodulator Used In Traditional Medicine
Authors: Dillasamola Dwisari , Nasif Hansen , Oktomalio Putri Biomechy , Noverial Noverial
Published: October 2024

Introduction:The Sungkai plant (Peronema canescens Jack) is widely used as an immunostimulant.. Sungkai (Peronema canescens Jack.) is one of the leading export commodities, especially for the Sumatra and Kalimantan regions. Sungkai leaf (Peronema canescens Jack.) is a natural source of flavonoids. Objective: To find out the efficacy of sungkai leaves so that they can be used as traditional medicine for the community. Methods: Literature Review. Data sources come from research journals on the efficacy of sungkai plants that can improve the body's immune system from various national and international sources. The data search strategy used was to search directly for gray literature through the Google search engine and use the Google Scholar, Pubmed and Science Direct databases with the keywords “Peronema canescensPlant”, “Traditional Medicine”, or “Efficacy of Sungkai Leaf”. Inclusion criteria included national journals on the efficacy of sungkai plants with Sinta accreditation 1-6, and Scopus-indexed international journals with rankings Q1-Q4. Exclusion criteria include journals that are not focused on discussing the efficacy of sungkai plants, unaccredited journals, and research journals with review methods. Results: From the national and international journals that have been reviewed, it was found that the sungkai plant has efficacy as an immunostimulant, in fertility, and has been tested for safety in pre-clinical animal tests and for generations by the community. Conclusion:Based on the literature that has been collected, it can be concluded that there are many studies on sungkai leaf extracts that are effective in maintaining endurance and have proven safety.
An Examination of the Potential Hair Damage Caused by Coconut Oil’s Dark Side
Authors: Ashok Borude Sanket
Published: October 2024

The moisturizing and nourishing qualities of coconut oil, a popular hair care product, have been praised. On the other hand, an increasing amount of data indicates that using coconut oil incorrectly or excessively can harm hair. This paper attempts to provide an overview of the available data about the possible harm that coconut oil may cause to hair, including pore blockage, protein accumulation, and moisture imbalance. A thorough review of the literature shows that the high protein content and thick, greasy texture of coconut oil can lead to clogged pores, inflammation, itching, and hair loss in addition to weighted-down hair, frizz, and breakage of the hair. Moreover, overusing coconut oil can throw off the natural moisture balance of the hair, causing frizz, brittleness, and dryness. This review emphasizes the need to use coconut oil with carefully to prevent potential harm to hair and offers safe usage guidelines.
Analysis of Pharmacist’s Integrated Patients Progress Notes (IPPN) on Hospitalized Patients with Lower Respiratory Infection
Authors: Nasif Hansen , Dillasamola Dwisari , Juwita Dian Ayu , Sari Yelly Oktavia , Serdiani Serdiani , Azzahra Rafifah , Emelda Emelda , Yulia Rahma
Published: October 2024

Upper respiratory tract infections are generally caused by viruses, while lower respiratory tract infections can be caused by bacteria, viruses, and mycoplasma which sometimes require patients to be hospitalized. This study aims to study the completeness and accuracy of writing Integrated Patients Progress Notes(IPPN) with the Subjective Objective Assessment Plan (SOAP) method made by hospital pharmacists. This study is a retrospective study, with a purposive sampling technique and results are analyzed descriptively. Data were taken from the medical records of patients with lower respiratory tract infections who were hospitalized in the Very Important People (VIP) room of Hospital X in Kampar Regency, Riau Province, Indonesia from 2019 to May 2020. 20 IPPNs were obtained, but only 16 met the inclusion criteria. The results showed that there were 3 (18.75%) IPPN data that were filled in completely, and the accuracy of writing that was declared correct was 2 (12.5%). It is hoped that pharmacists can improve their knowledge of writing SOAP in IPPN better.
التربية الفكريّة في سياق النّهوض الحضاريّ المنشود - تحرير: فتحي حسن ملكاوي
Authors: مصطفى اللحام حسام
Published: October 2024

يتناول هذا الكتاب موضوع "التّربية الفكريّة في سياق النّهوض الحضاريّ المنشود"، انطلاقاً من الإيمان بأنّ التربية هي المدخل الأساس في التغيير الاجتماعيّ والثقافيّ والحضاريّ.  وقد ساهم في تأليف الكتاب علماء وباحثون من المغرب والجزائر وتونس والأردنّ؛ إذ تنوّعت أفكارهم وتضافرت جهودهم؛ لبناءِ تصوّر تربويّ منهجيّ متكامل، يرمي إلى أن يشكّل مشروعاً للتربية الفكريّة؛ تعزيزاً للجهود المبذولة في سبيل الإصلاح الحضاريّ في العالم الإسلاميّ.
جاء الكتاب في مقدّمة وعشرة فصول وخاتمة، وعُني فتحي ملكاويّ بتحريره، وَكَتَب مقدّمته وخاتمته والفصل السّادس، ومهّد لكلّ فصل من فصول الكتاب بموجز وَسَمَهُ بـ"تقديم التّحرير" عَرَّف فيه بفكرة الفصل وموقعه في خطّة الكتاب الكلّيّة.
عروض مختصرة
Authors: الحوامدة إيصال صالح
Published: October 2024

الجغرافيا والمذهب: التطور التاريخي للأشعرية في خراسان، عبد الله عمر ياووز، بيروت: مركز نماء للبحوث والدراسات، ط1، 2024م، 315 صفحة.
نقد المذهب الأشعري في الفكر السَّلفي المعاصر، الحسين بودميع، عمان: دار الرياحين للنشر والتوزيع، ط1، 2023م، 574 صفحة.
دليل كامبريدج إلى علم الكلام الإسلامي، ‏تيم وينتر، بيروت: دار الروافد الثقافية، ط1، 2024م، 432 صفحة.
رسالة الشافعي في السياق والمنهج والخطاب دراسة في نظرية المعرفة الأصولية، الحسّان شهيد، عمان: مكتبة مسك للنشر والتوزيع، ط1، 2024م، 560 صفحة.
مرجع أكسفورد في الفقه الإسلامي وأصوله وتاريخه، تحرير: أنور إيمان،رومي أحمد، ترجمة: أسامة السيد وأحمد إبراهيم ومحمود عبد العزيز، بيروت: مركز نهوض للدراسات والنشر، ط1، 2024م، 1695 صفحة.
المذهب الظاهري "(القرن الثالث/ التاسع) – (القرن العاشر/ السادس عشر)" نظرية نصوصية للفقه الإسلامي، عمرو عثمان، بيروت: مركز نماء للبحوث والدراسات، ط1، 2024م، 311 صفحة.
ترك إعمال الدليل في اجتهاد الصحابة وتخريجاته عند العلماء، محمد بن سالم آل رميح، عمان: مسك للنشر والتوزيع، ط1، 2024م، 1192 صفحة.
التشبيه في تاريخ الإسلام: تحدي أهل الحديث (700-1350م) - (80-750ﻫ)‏، ليفنات هولتزمان، بيروت: دار الروافد الثقافية، ط1، 2023م، 448 صفحة.
الخطاب البصري في أعمال الخزّاف، شيماء حمزة رديف، ومحمد عاد سرتيب، بابل: دار الصادق الثقافية، ط1، 2022م، 235 صفحة.
تأثير زخارف سامراء الجصّية في الفنون العربية الإسلامية، طاهر محمد هارون الغنميين، عمان: دار شهرزاد للنشر والتوزيع، ط1، 2021م، 219 صفحة.
العمارة العربية الإسلامية: الفكر المعماري العربي الإسلامي، بديع العابد، عمّان: وزارة الثقافة، ط1، 2022م، 534 صفحة.
الأثر الكلامي والفلسفي للإمام الرازي على علماء ما وراء النهر، محمد علي السيد الكيلاني، عمّان: نور اليقين للطباعة والنشر والتوزيع، ط1، 2023م، 592 صفحة.
Maturidi Theology: A Bilingual Reader (Sapientia Islamica, 4), Lejla Demiri, Philip Dorroll & Dale J. Correa (eds.), Mohr Siebrek Ek, 2022, 257 pages.
Philosophical Theology in Islam: Later Ash'arism East and West (Islamicate Intellectual History), Ayman Shihadeh & Jan Thiele (eds.), Leiden: Brill, 2020, 450
Engagement with Problematic or Contradictory Hadiths in Medieval and Modern Times, Khairil Husaini Bin Jamil, Muhammad Adil Bin Musa, Muhammad Fawwaz Muhammad Yusoff (eds.), Kuala Lumpur: Islamic Book Trust, 2024, 392
Mosque: Approaches to Art and Architecture, Idries Trevathan (ed.), London: Routledge, 2024, 212
The production of Meaning in Islamic Architecture and Ornament, Yasser Tabbaa, Edinburgh: Edinburgh University Press, 2021, 536
Islamic Jurisprudence, Islamic Law, and Modernity (Resources in Arabic and Islamic Studies, 15), by Mohammad H. Fadel, Columbus: Lockwood Press, December 2023, 390
تطوُّر المنهج العقلي في الدرس الكلامي الأشعري
Authors: الشهبي محمد
Published: October 2024

كان منهج الفكر الكلامي في بِنيته وأساليبه شديد الصلة بالمشكلات الطارئة في حياة المسلمين الفكرية والعلمية. وقد تطوَّرت مناهج الأشاعرة حين أخذوا على عاتقهم مهمة حماية العقيدة الإسلامية والدفاع عنها، وهو مقامٌ للاستدلال في سياق مواجهة شُبُهات الخصوم، تابعٌ لكيفية إقناع الـمُشكِّك والـمُعانِد، لذلك وقعت فيه المرونة باستعمال بعض الأدلَّة التي قد لا يلتزم الطرف الـمُستدِلُّ بها أحياناً، فكانت مساحة مناهج الاستدلال ضد الخصوم أوسع.
وكان سَيْر الـمُتكلِّمين الـمُتقدِّمين من الأشاعرة على الطريقة الجدلية، اعتماداً على آليَّة الاستدلال العقلي القياسي وما تفرَّع منها، هو ما جعلهم جميعاً يُصادِمون المنطق الأرسطي، ويُعرِضون عنه؛ إذ كان منهجهم -منذ البداية- منهج الدرس الأصولي نفسه، وجاء ضَمُّ القياس العقلي -بوصفه آليَّة إضافية جديدة- في الدرس الكلامي للسبب نفسه في الدرس الأصولي.
أمّا عند الـمُتأخِّرين فقد تغيَّرت البِنية الفكرية للمُخالِف عند شيوع الفلسفة في الأُمَّة الإسلامية؛ ما فرض على الـمُتكلِّمين الأشاعرة تجديد الدرس الكلامي على المستوى الوظيفي والمنهجي، فكان ذلك دافعاً إلى اعتماد الـمُتكلِّمين آليّات استدلالية بديلة تنسجم مع طبيعة الدرس الكلامي في هذه المرحلة.
مقولة "إثبات ما أثبته اللَّه لنفسه"
Authors: الخطاف حسن
Published: October 2024

بنى الـمُتأخِّرون، ولا سيّما ابن تيمية (ت: 728ﻫ)، ومَنْ سار على نهجه، فهمهم للصفات الإلهية الخبرية على مقولة "إثبات ‌ما ‌أثبته ‌اللَّه لنفسه"، حتّى غدت بمنـزلة النص الـمُحكَم، وصارت فاصلاً بين السُّني والبِدْعي. وانطلاقاً ممّا سبق، جاءت إشكالية الدراسة بسؤال رئيس، هو: كيف تأسَّست هذه المقولة وتطوَّرت؟ وستحاول الدراسة الإجابة عن السؤال المطروح بعد الخوض في تفاصيل المقولة المذكورة آنفاً. وتحقيقاً لذلك؛ جاءت الدراسة في أربعة مباحث، لكل مبحث منها مطلبان. وتتمثَّل أهمية الدراسة في البحث عن جذور هذه المقولة، واكتمالها، وكيف تحوَّلت إلى قانون يُفرَز الناس وِفقها؟ وممّا يزيد من أهمية الدراسة أنَّها تبحث في القرون الثلاثة الأولى عن تاريخ المقولة وتدرُّجها، ومدى استحقاقها هذه المنـزلة. وأبرز ما توصَّلت إليه الدراسة هو أنَّ عصر الصحابة لم يشهد حضوراً لهذه المقولة، وأنَّ البذور الأولى كانت على يد وهب بن مُنبِّه (ت: 111ﻫ)، واكتملت على يد الدارمي (ت: 280ﻫ)، وأنَّ نشوءها ترافق مع نـزعة التشبيه لله، وأنَّها جاءت رَدَّ فعل على نـزعة التنـزيه الـمُبالَغ فيها على يد القدرية والمعتزلة. وقد أوصت الدراسة بالبحث في هذه المقولة عند ابن تيمية.
وأكّدت الدراسة ضرورة الابتعاد عن كل ما يُفرِّق وحدة المسلمين؛ فالوحدة مقصد شرعي، لا سيَّما في وقتنا الـمُعاصِر الذي أصبحت فيه الوحدة ضرورة دينية وأخلاقية واجتماعية.
التربية اليابانيَّة المركَّبة: الاقتراحات والدروس المستفادة - تأليف: ناصر يوسف
Authors: أبو غزالة ماجد
Published: October 2024

يُشكّل التعليم بوصفه مهمةً مهنيةً وإبداعية، تنشغل بصناعة الإنسان والنخب والمستقبل، البنيةَ التحتية لنهضة اليابان الحديثة. والمحور المركزي الذي يدور في فَلَكِه هذا الكتاب في فصوله الستّة، هو كيف نستثمر الجهد الياباني ونفهمه ونتعلّم منه؟ تعدّ التجربة اليابانية من النماذج العريقة التي غفل الوطن العربي والشرق الإسلامي عن الاستئناس بها. وأدركت ماليزيا -عملياً- بموازنتها بين القيم والعلم، إلى أنَّ التعليم النوعي صنع نهضة اليابان الحديثة. والأنموذج الياباني في التربية والتعليم يُعدُّ الأفضل أداء في العالم من حيث النوعية والجودة والكفاية والمساواة في فرص التعليم، كون التجربة التربوية اليابانية سلكت طريق الإبداع الفردي مصحوباً بالجهد القيمي الجماعي الموروث عن الأسلاف؛ ولكن بـ"طريق الأمام"، وهذا ما عناه المؤلِّف بالتربية الـمُركّبة. فالتركيب التربوي تراكمٌ إبداعيّ محلّيّ أسهمت القيم في تبيئته، فاستحال إلى إبداع محلي بطرق وأساليب الجهد القيمي. والتعليم في اليابان قائم على القيمة؛ أي بذل الجهد في إطار القيم، فربط الجهد بالقيم يعني ربط المعرفة بالأمّة؛ لأنّ القيم هي القاسم المشترك بين الفرد والأمّة، وبين المعرفة العالمية والإبداع المحلّي. ومن غير جهد قيمي يُبذل تستحيل المعرفة المكتسبة إلى ترفٍ معرفيّ. ومن ثم، لا يعدو جهد الفرد في اكتساب المعرفة أن يكون كسباً شخصياً.
Digital transformation and COVID-19: experience and prospects for the development of “society 5.0” in japan. analysis of the situation in Ukraine
Authors: Balanchuk I. S.
Published: October 2024

In connection with the transformation of the civilizational landscape of the world, the need for the evolution of modern society is growing many times over, and Japan is a country where a new type of society is being formed at an unprecedented pace. The paper proposes to consider the features of the creation and development of “society 5.0” in the context of analyzing the implementation of the direction in Japanese practice by summing up the main components of the sphere. The main methods were the method of system analysis, with the help of which the key components of the digitalization of modern society in Japan were studied, and the historical method, with the help of which were outlined features of the implementation of information technology in all spheres of life of the country and society. The work examines the main semantic elements of such a phenomenon as “digital society” — definition, terms, characteristic features, common and distinctive factors. It was recorded that the quality indicators of modern humanity at the beginning of the 21st Century ceased to fully satisfy its needs and demands, and in connection with this, the need to create a new form of society is arose — a symbiosis of humans and digital technologies. In the context of the moral side of the issue, social and cultural problems arise, namely, how the synergistic combination of a living organism and robotic elements will affect Japanese society in the future. Through the prism of using the experience of digitalization of social, political and other spheres of interaction in Japan, it is summarized that Ukraine has all the prerequisites for their successful application in national practice. The results and conclusions of the work can be used as a practical basis for future scientific research, as well as in the context of developing state and social development strategies for the coming years.
Development of an information system for integral rating assessment of investment attractiveness of an enterprise
Authors: Savchuk L. M. , Lozovska L. I. , Udachyna K. O. , Savchuk R. V.
Published: October 2024

Numerous methods of financial diagnostics of business entities have been analyzed in this article, methodological approaches to integral assessment have been considered. A study of methods of rating assessment of enterprise activity by different methods was carried out.
Emphasis on the integrated assessment of the enterprise was placed. The use of the Harrington’s desirability function to build a generalized indicator of investment attractiveness of an enterprise was proposed. An economic-mathematical model of rating assessment has been developed, the use of which allows: to determine the indicators for assessing the investment attractiveness of economic entities to obtain their ratings; to calculate normalized indicators of investment attractiveness, if necessary; to calculate the integral indicator of investment attractiveness. To test the adequacy of the model, an experiment was conducted, which confirmed the adequate representation of the integrated indicator depending on the input data. The rating process was automated by creating an information system that allows determining an integrated assessment of the investment attractiveness of an enterprise, taking into account its components. The results obtained in this way allow making decisions on the level of efficiency of certain enterprises, and the developed automated system increases the level of information support in monitoring the overall assessment of the enterprise.
Clustering First-order reversal curve diagram using the Gaussian mixture model and the Davies–Bouldin index
Authors: Ying Ruixuan , Taniguchi Takuya , Nabeta Koki , Ishigami Keisuke , Kikuchi Nobuaki , Okamoto Satoshi
Published: October 2024

In our energy-consuming society, understanding magnetization reversal in permanent magnets is crucial for improving energy conversion efficiency between electric energy and mechanical energy. First-order reversal curves (FORCs) have enabled qualitative studies of reversal mechanisms, however, further understanding based on quantitative analysis is still difficult due to the complexity of FORC diagrams. We introduce a machine-learning-based approach combining the Gaussian mixture model and the Davies–Bouldin index to separate characteristic features in FORC diagrams of Nd-Fe-B magnets. The clustering method is evaluated using several FORC diagrams obtained at different temperatures, and we also demonstrated hysteresis loop reconstruction using the clustered FORC diagrams.