Design and Rationale of the National Tunisian Registry of Percutaneous coronary Intervention: Protocol for a Prospective, Multicenter Trial (Preprint)
Authors: Hammami Rania , Boudiche Slim , Tlili Rami , Ben Hlima Nejeh , Jamel Ahmed , Rekik Bassem , Gribaa Rym , Ben Mrad Imtinen , Charfeddine Selma , Ellouz Tarek , Bahloul Amin , Ben Slima Hedi , Langar Jamel , Ben Ahmed Habib , Ibn Bel Hadj Zied , Hmem Mohamed , Ben Abdessalem Mohamed Aymen , Maaoui Sabri , Fennira Sana , Laroussi Lobna , Hassine Majed , Ouannes Sami , Drissi Faouzi , Mallek Souad , Mahdhaoui Abdallah , Dghim Mariem , Jomaa Walid , Zayed Sofiene , Kateb Tawfik , Bouchahda Nidhal , Azaiez Fares , Ben Salem Helmi , Marouene Morched , Noamen Aymen , Abdesselem Salem , Denguir Hichem Denguir , Hadj Amor Hassen , Farhati Abdeljelil , Amara Amine , Bejjar Karim , Ben Hamda Khaldoun , Hamza Chiheb , Ben Jemaa Mohsen , Fourati Sami , Elleuch Faycal , Grati Zeineb , Chtourou Slim , Marouene Sami , Sahnoun Mohamed , Hadrich Morched , Maalej Abdelkader , Bouraoui Hatem , Kamoun Kamel , Hadrich Moufid , Ben Chedli Tarek , Drissa Mohamed Akrem , Charfeddine Hanene , Saadaoui Nizar , Gargouri Achraf , Siala Ahmed , Ayari Mokdad , Marsit Nabil , Mnif Sabeur , Sahnoun Maher , Kamoun Helmi , Ben Jemaa Khaled , Gharbi Mostari , Hamrouni Nebil , Maazoun Yamen , Ellouz Yassine , Smiri Zahreddine , Hadiji Amin , Jerbi Bassem , Ayadi Wacef , Zouari Amir , Abbassi Chedly , Boujelben Masmoudi Fatma , Battikh Kais , Kharrat Elyes , Mnif Sabeur , Gtif Imen , Milouchi Sami , Bezdah Leila , Kachboura Salem , Maatoug Faouzi , Kraiem Sondes , Jeridi Gouider , Nafati Elyes , Kammoun Samir , Ben Ameur Youssef , Fehri Siala Wafa , Gamra Habib , Zakhama Lilia , Addad Faouzi , Mourali Mohamed Sami , Abid Leila 
Published: October 2020

BACKGROUND

Coronary diseases remain the first cause of death in the world; the management of this condition has improved, thanks to new technical tools and multicentric registries. Recently in Tunisia, the number of intervention procedures has markedly increased, giving the explosion of cardiovascular risk factors among Tunisian people.

OBJECTIVE

The aim of the study was to investigate the in-hospital and one-year
clinical outcome of patients treated with percutaneous coronary intervention (PCI)
in Tunisia.

METHODS

We will conduct a prospective, multicentric, observational study including patients > 18 year-old who underwent a PCI between 31January and 30 June 2020. The primary end point are the occurrence of a major adverse cardiovascular event , defined as cardiovascular death, myocardial infarction, cerebrovascular accident, and target vessel revascularization with either repeat PCI or coronary artery bypass surgery (CABG). Secondary end-points consist in procedural success rate, stent thrombosis, and the rate of redo-PCI/CABG for in-stent restenosis.

RESULTS

Results will be available at the end of the study as well as the demographic profile and general risk profile of Tunisian patients undergoing PCI. The complexity level of procedures, as left main, bifurcation, chronic occlusion PCI will be analyzed and immediate as well as long term results will be determined. NATURE-PCI will be the first national multicentric registry of angioplasty in Africa.

CONCLUSIONS

This study would add data and provide a valuable opportunity for real-world clinical epidemiology and practice in the field of interventional cardiology in Tunisia with insights into the uptake of contemporary coronary artery disease in this developing region.

CLINICALTRIAL

clinicaltrials.gov