bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the Effect of Biological Nutrient Removal (BNR) on Wastewater Quality
Authors:   Department of Civil Engineering, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria, Mmonwuba Nwanneka Chibuzo , Uwanuakwa Arinze ,   Department of Civil Engineering, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria, Nwafor Lucky ,   Department of Civil Engineering, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria, Chidiebere Muodebelu Vitalis ,   Department of Civil Engineering, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria, Nwosu Chinyere ,   Department of Civil Engineering, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria
Published: January 2025

Industrial wastewater, particularly brewery wastewater contains high-strength organic, inorganic, and biological compounds which are harmful to the environment. Different technologies such are employed towards treating brewery wastewater before discharge into water bodies, but biological method has proven to be more environmental-friendly, cost-effective and easier to operate. This research project assessed the impact of biological nutrient removal (BNR) on wastewater quality, and it involved laboratory scale sequencing batch reactor (SBR), operated in a cyclic aerobic-anaerobic set-up inoculated with activated sludge to remove orthophosphates and nitrate compounds. Raw brewery wastewater samples were collected from Awo-Omama brewery plant of Nigerian Breweries Plc, Imo State, Nigeria. They were analyzed using standard methods described by American Public Health Association (APHA) to determine the removal efficacies of orthophosphates (PO43-), ammoniacal-nitrogen (NH3-N), total Kjeldahl nitrogen (TKN), total nitrogen (TN), total organic nitrogen (TON), total inorganic nitrogen (TIN) and NO3-N+NO2-N. Results revealed that 69% PO43-, 69% NH3-N, 59% TKN, 60% TN, 64% TON, 67% TIN and 56% NO3-N+NO2-N. These removal efficacies were attained for a hydraulic retention time of 18 hours for both SBRs with a solids retention time of 5 days for SBR-1 and 7 days for SBR-2. Findings of this study showed that the cyclic aerobic-anaerobic set-up on a laboratory scale SBR, inoculated with activated sludge for treatment of brewery wastewater for biological nutrients was feasible. It is recommended that investigation on BNR using brewery wastewater with a well-balanced C: N: P ratio should be done to improve BNR efficacies.
Prevalence of Pelvic Inflammatory Disease among Women of Reproductive Age Attending Gynaecology Clinic at Lagos State University Teaching Hospital, Ikeja, Lagos
Authors:   Department of Nursing, Faculty of Clinical Sciences, Lagos State University College of Medicine, Ikeja, Lagos., Iwu Rosemond Chidimma , Amie Dorcas Chika ,   Department of Nursing, Faculty of Clinical Sciences, Lagos State University College of Medicine, Ikeja, Lagos., Eduwa Oruese Abigail ,   Department of Midwifery, Lagos State College of Nursing, Igando, Lagos., Sanusi-Borokini Monsurat Abiodun ,   Department of Midwifery, Lagos State College of Nursing, Igando, Lagos., Augustine Felicia Adedoyin ,   Department of Midwifery, Lagos State College of Nursing, Igando, Lagos., Zakari Alice Olukemi ,   Department of Nursing, Lagos State College of Nursing, Igando, Lagos.
Published: January 2025

Pelvic inflammatory disease (PID) is a polymicrobial infection of the female upper genital tract, mostly caused by Neisseria gonorrhoea and/or Chlamydia trachomatis, while other endogenous flora from the vagino-cervical areas might also be implicated. This study examined the prevalence of PID among women of reproductive age attending Gynaecology Clinic at Lagos State University Teaching Hospital (LASUTH). The study adopted a cross-sectional research design. A total of 218 respondents participated in the study. A 43-item questionnaire was used for data collection, and then analyzed using the statistical package for social sciences (SPSS) version 25 while adopting Chi square for the inferential statistics. Results of the study showed that there was high prevalence of PID 164(75%) among the respondents and 120(55%) had treated the disease previously. The study also revealed that the respondents had poor knowledge about the risk factors and effects of PID; they understood that lower abdominal pain 174(80%) and foul smelling discharge 164(75%) were the major experienced symptoms. Whereas 131(60%) disagreed that multiple sexual partners could cause it. Similarly, 179(82%) were undecided on whether PID could cause complications in pregnancy and 159(73%) strongly disagreed that PID can cause infertility. Also, all respondents 218(100%) agreed that use of pain relief and antibiotics could cause PID. Hypothesis testing revealed that there was no significant relationship between the respondents’ educational level and their knowledge about PID. Conversely, there was a strong association between the occurrence of PID and the women’s age. It was concluded that there is high prevalence of PID among women in Gynecology Clinic at LASUTH (age<25years) who portrayed poor knowledge on the risk factors and effects. It was therefore recommended that the management of LASUTH should invest more time and resources in educating women on the risk factors, preventive measures and complications of PID.
Peran Konseling Pendeta dalam Bimbingan Rohani dan Kebiasaan Positif Bagi Pemuda Kristen
Authors: Nanariain Tahith Aldrich , Pardosi Milton T.
Published: January 2025

In the dynamics of modern life, the challenges faced by the younger generation in maintaining a balance between spiritual aspects and the material world are increasingly complex. Social changes, environmental pressures, and the influence of technology have significantly influenced their thinking and behaviour. In this context, the role of the congregational pastor or pastor as a spiritual figure is crucial in restoring spirituality and strengthening positive habits for young people. This research uses a descriptive qualitative approach to explore young people's experiences and perceptions of congregational pastoral counselling and its impact on the formation of spirituality and positive habits. The research results show that congregational pastoral counselling not only addresses spiritual problems but also helps strengthen the foundation of their spiritual life. This research also identified patterns and themes in positive behaviour change through analysis of counselling participants' narratives. In conclusion, pastoral counselling has an important role in helping young people overcome the challenges of modern life and develop their spiritual potential.
Strategi Pembelajaran Menggunakan Metode Pembelajaran Berbasis Permainan dengan Media Pembelajaran Quizizz
Authors: Limin Steve , Fitrisiswanty
Published: January 2025

The use of strategies in the learning process is a must to facilitate the achievement of optimal results. A successful learning process requires conditions that do not stress students, and this is the reason why a strategy is important in its role in achieving good learning outcomes in the classroom. A teacher can sometimes lose direction, the trigger for which is very clear, namely without a clear strategy in the learning process, and the goals set at the beginning of the lecture are certainly difficult to achieve. In the context of classroom learning, the use of learning media becomes very important. Every learning media used today has various types, forms, or models, including audio, visual, and motion. The aim of this research carried out by researchers is to discover and explain the use of one of the multimedia learning media which is packaged in the form of games and is free, namely the Quizizz platform, which is a learning technology implemented in Christian leadership courses. Simply put, the aim of using this learning media is so that each student has a greater opportunity to interact, absorb and understand what is conveyed by the lecturer. Researchers conducted descriptive qualitative research through direct observation, individual interviews, and literature study. The aim of this research carried out by researchers was to find out how effective the use of Quizizz! as an alternative as a varied learning medium in the classroom and creates a pleasant learning atmosphere in the classroom, and the results of this research show that students can more easily absorb the material in learning Christian leadership courses through the use of the Quizizz! The results of this research provide a significant contribution to higher education institutions in implementing innovative digital learning.
Pendidikan Kristen sebagai Solusi Progresif dalam Menanggapi Tantangan Kesenjangan Sosial
Authors: Sianturi Novita , Wagiu Meily M. , Manua Englin R. , Veronika Thelma , Solang Zefanya
Published: January 2025

This article discusses the proactive movement of Christian religious education in responding to social inequalities. Christian religious education has the potential to transform the attitudes and behaviors of individuals and communities, motivating them to actively combat social injustice. Through the teaching of Christian values such as love, justice, and solidarity, Christian religious education can build strong social awareness and encourage concrete actions to address social disparities. This research employs a qualitative literature review aimed at elucidating the progressive proactive stance of Christian religious education in responding to the challenges of social inequality. The discussion yields several opportunities for Christian religious education in addressing social disparities: sensitivity to social issues, fostering inclusivity, empowering individuals in need, and engaging in dialectics.
Sarana dan Prasarana dalam Menunjang Hasil Belajar Pendidikan Agama Kristen bagi Peserta Didik
Authors: Yessi Carolina  , Merilyn  , Triadi Defri
Published: January 2025

This study aims to analyze the infrastructure that supports student learning outcomes in Christian Religious Education lessons at SMAN 1 Palangka Raya. The research method is qualitative with descriptive research type. Data collection techniques with interviews, observation, and documentation. The results of the research of existing infrastructure facilities at SMAN 1 Palangka Raya are in good condition, but still do not meet the standards in accordance with the Regulation of the Minister of National Education Number 24 of 2007 Standards for facilities and infrastructure of SMA / MA General Education. In this case there are some that still need to be completed and considered such as religious study rooms whose facilities such as air conditioning and LCD that need to be repaired or replaced, as well as a place of worship that needs to be provided specifically for students who are Christian. The completeness of the existing infrastructure at SMAN 1 Palangka Raya can meet the needs of students and teachers, so that in the process of teaching and learning activities can run effectively and efficiently, and the learning outcomes obtained by students XI MIPA 2 through the learning process are supported by educators and infrastructure.
Peran Roh Kudus Berdasarkan Teks Yohanes 14:26 dalam Pendidikan Kristen Anak Usia Dini
Authors: Wiranto Derry , Kristanto Samuel Hans
Published: January 2025

This study examines the implications of the Holy Spirit's role as Teacher and Reminder (John 14:26) for Early Childhood Christian Education (ECCE). Through literature review and theological analysis, it explores how this understanding transforms ECCE practices, curriculum development, and pedagogical approaches. The research reveals that integrating the Holy Spirit's work requires a holistic approach, including responsive curriculum design, experiential teaching methods, and spiritually nurturing environments. It emphasizes educators' roles as facilitators sensitive to the Holy Spirit's guidance and the need for collaboration between ECCE institutions, families, and churches. The study addresses challenges in implementing a Spirit-centered approach and offers practical solutions. It proposes a paradigm shift in ECCE from knowledge transfer to facilitating transformative spiritual experiences, thus laying a robust spiritual foundation for the next generation.
Arbitration of Patent Validity Disputes in China: Practice, Problems and Prospects
Authors: Li Yue
Published: January 2025

The arbitration system has emerged internationally as a convenient and efficient way to resolve disputes. To align with the development trend of the international arbitration system, China has promulgated the draft of its third revised Arbitration Law for public comment. In this regard, whether patent validity disputes are arbitrable has once again become a topic of discussion. This paper primarily investigates why it is difficult to develop arbitration of patent validity disputes in China. In addition, it elucidates the arbitrability of patent validity disputes in China from the perspectives of public policy, efficiency, etc. These efforts are intended for providing theoretical basis and suggestions for the development and improvement of patent arbitration system. Through literature analysis method and comparative analysis, this thesis finds that arbitration of patent validity disputes is feasible in China. It further suggests that China should improve its legislative framework for patent arbitration in line with the third amendment and uphold its commercial reservation declaration under the New York Convention.
Strategic Alliances and Evolving Influence: The Role of Brazil, India and China in Shaping Global Trade Through the WTO
Authors: Chu Yuqian
Published: January 2025

This article delves into how developing countries can effectively advance their interests by leveraging strategic alliances and multilateral negotiations within the World Trade Organization (WTO) framework, emphasizing the roles of Brazil, India, and China in the Doha Development Agenda. By closely examining the influence these nations have wielded through alliances like the G20, this study explores their efforts to address crucial issues, including reducing agricultural subsidies, enhancing non-agricultural market access, and improving trade in services. Through these alliances, developing countries have collectively pushed back against entrenched trade inequities, showcasing both their strengths and limitations within the multilateral trading system. The research highlights how these strategies reveal a significant shift, as developing nations now command a larger presence in shaping global trade norms. At the same time, it exposes the inherent trade-offs these countries face: balancing their pursuit of national economic interests with their advocacy for a more equitable global trade structure. This analysis underscores the complex dynamics of power, negotiation, and compromise within the WTO, illustrating how developing countries must navigate the dual imperatives of self-interest and global equity to sustain their long-term influence on the multilateral stage.
Deepfake: Exploring the Societal Risks and Ethical Dilemmas of This New AI Technology
Authors: Li Tanghaorui
Published: January 2025

On Social media platforms, fake news produced by AI has spread rapidly throughout these channels, negatively impacting millions of users. Deepfake, a form of AI communication that integrates deep learning, has become a hot topic at the communication theory and practice. This technology can produce artificial videos, images and sounds with high efficiency. While most research on deepfake focuses on detection systems in computer science, this paper argues that it needs to be analyzed from the perspectives of culture and communication. This paper uses literature review looking at how deepfake technology spreads false information, especially in influencing politics, invading people's privacy, and damaging trust in social media. By reviewing global studies and events, the research demonstrates that deepfake technology poses a significant danger to public opinion and personal privacy. The study also offers suggestions for addressing these issues, emphasizing the need for technological advancements and regulatory frameworks to guide future media and information management. Recommendations include continuous development of deepfake detection systems, legal constraints, and improving digital media literacy.
Analysis of the Preference of Chinese Students Choose to Study in the United Kingdom in the Post-Pandemic Era
Authors: Zhang Yichen
Published: January 2025

With the continuous stability of the post-epidemic era, the social and economic levels of various countries are gradually recovering, and the rate of studying abroad is also gradually rising. The number of international students studying in the UK continues to increase. Among them, the number of Chinese students has always been at the top. This article explores why Chinese students choose to study in the UK, especially for higher education. The article examines key reasons behind this trend, including the perceived benefits of personal and career development, the quality of higher education, and Employability after graduation. Additionally, it discusses the impact of the UK's recent policy changes, such as visa restrictions, on students' choices. Although the overall trend of Chinese students studying in the UK remains strong, the potential challenges, such as employment pressures and evolving immigration policies, may affect future preferences. This article suggests that while the UK's reputation as a high-quality education provider continues to attract Chinese students, the long-term impacts of policy shifts and social issues remain to be seen.
Body and Perception -- A Study of Merleau-Ponty's Theory of the Body
Authors: Wang Yilin
Published: January 2025

Maurice Merleau-Ponty's theory of the body brings a new perspective to Western philosophy and phenomenology. Merleau-Ponty inherited Husserl's phenomenology of consciousness and emphasized the idea of the oneness of mind and body. In this theory, Merleau-Ponty put forward the concept of flesh to oppose the Cartesian dichotomy of body and mind. In his understanding of perception, Merleau-Ponty proposed the concept of perceptual field, in which Merleau-Ponty believed that perception is embodied in the form of a field in which things can be presented in the most primitive and complete way, and perception is direct. At the same time, the concept of flesh of the world is also put forward. Flesh is the basic nature of people and the world, and the communication between human beings and the external world is the flesh and the flesh of the world. The communication between human beings and the external world is the direct mutual perception and interaction between the flesh and the flesh of the world. According to Merleau-Ponty, in communication, the body is the medium for perceiving and understanding symbols, and the meaning of symbols is formed through bodily experience and culture. The speech act is a complex expression of the body's interaction with the world that allows for a shared experience between the speaker and the listener. Merleau-Ponty's concept emphasizes the monadic embodiment of perception and thought, matter and consciousness in the body, breaking through the limitations of the a priori philosophical thinking of Western logic.
The Influence of Parental Psychological Control on Junior High School Students' Learning Motivation and Self-Efficacy
Authors: Chen Jing
Published: January 2025

Background:Parents of junior high school kids' expectations and worries about their teenage children frequently develop into anxiety and become the basis of their psychological control in present-day society due to the growing stress of social competition. Moreover psychological control is not conducive to the sound development of teenagers, which also has a great impact on their learning motivation (LM) and self-efficacy (SE). Methods: This paper adopts the method of literature review, selects the relevant representative literature for detailed and comparative analysis and summary, in order to explore the influence of parental psychological control (PPC) on junior high school students' LM and SE. Results: The study found that PPC indirectly reduced students' LM through academic emotion, achievement attribution and learning attitude. At the same time, the research reveals that proper PPC promotes the development of junior high school pupils' SE, whereas excessive PPC is not SE. Therefore, it is important to investigate the effects of PPC on middle school students' LM and SE for their children's growth. This paper can better help their children's healthy growth, let parents understand the negative effects of excessive PPC and improve their behavior.
What Makes the Movie More "Colourful"? A Discussion on Diversity and Social Psychological Theories
Authors: Wang Jingyuan
Published: January 2025

Movies are one of the most widely accepted and loved forms of art, and their extremely high level of acceptance and circulation has made them a vehicle for many political and artistic ideas. The accessibility of movies also makes the narratives they convey more deeply rooted in peoples minds. This is reflected not only in the educational and pedagogical functions of schools, but also in the daily impact on peoples values and worldviews. One noticeable trend about movies is that there is an increasing level of ethnic diversity in them. That is, colourful as the title suggests. This paper addresses this phenomenon by briefly discussing the reasons for and possible implications of this trend from a social psychological perspective based on social identity theory along with race and media studies. With reference to previous research, it may be concluded that the increased level of racial diversity among actors may be due to the fact that the profit-oriented characteristics of the movie industry compels practitioners to take into account the socially and politically influential factors of minority groups. However, as the dominant narrative is still white-dominated, the roles played by minorities in films are often influenced by stereotypes or made for specific audience groups. On top of this, some minorities, such as Asians, are subject to wider prejudice. This is reflected not only in the films themselves and casting, but also in audience preferences.
The Impact of Domestic Violence on Juvenile Delinquency - A Systematic Review
Authors: Su Shijia
Published: January 2025

This systematic review and meta-analysis examine the impact of domestic violence, with an emphasis on childhood physical and sexual abuse, on juvenile delinquency. By integrating various theoretical frameworks, including Aker's social learning theory and the cycle of violence theory, this research investigates the impact of exposure to abusive settings on the development of antisocial behaviors. The meta-analysis specifically focuses on the relationship between childhood sexual abuse (CSA) and tendencies toward delinquent behaviors, revealing significant associations between CSA and increased delinquency risk. The analysis highlights the significant mediating influence of callous-unemotional traits in connecting childhood maltreatment to aggressive behaviors. The results demonstrate that childhood abuse, encompassing both sexual and physical abuse, has lasting effects on psychological well-being and criminal behavior during adolescence. Despite high heterogeneity in effect sizes, the analysis underscores the consistent protective effect of early interventions in reducing long-term delinquency risks. This analysis underscores the urgent necessity for proactive strategies aimed at combating childhood abuse and reducing its capacity to cultivate delinquent behaviors.
Traditional Cultural Elements and Their Modern Adaption in Black Myth: Wukong
Authors: Li Huiqiang
Published: January 2025

On August 20th, 2024, the highly anticipated release of Black Myth: Wukong by Game Science generated significant excitement among players. This paper aims to conduct a comprehensive analysis of Game Science, using a SWOT framework. Additionally, the 4P theory will be utilized to analyze how Black Myth: Wukong contributes to the preservation and development of Chinese culture, as well as its market performance. The game, inspired by the classic Chinese novel Journey to the West, not only captivates players with its immersive gameplay and stunning visuals but also serves as a medium for cultural dissemination. By examining the strategic elements such as product design and features, pricing strategy, distribution channel, and promotional activities, this study seeks to highlight the game's role in bridging traditional cultural narratives with modern gaming experiences. Furthermore, the analysis explores the broader implications of its success on the gaming market and its potential influence on future cultural projects within the industry. The paper is expected to provide insights into the intersection of gaming and cultural heritage, demonstrating how innovative game design can foster a deeper appreciation for traditional narratives while driving economic growth in the entertainment sector.
The Impact of Parental Incarceration on Asian American Children: Cultural Barriers and Social Work Interventions
Authors: Rao Xuemei
Published: January 2025

This study examines the multifaceted challenges faced by children of incarcerated Asian American parents, focusing on the intersection of cultural, psychological, and systemic barriers. Although Asian Americans have lower incarceration rates compared to other racial groups, cultural stigmas and the pervasive "model minority" stereotype significantly hinder access to essential mental health, educational, and social support services. These children often experience financial instability, heightened psychological distress, and social isolation due to both societal and cultural pressures. This research evaluates existing support mechanisms, such as Temporary Assistance for Needy Families (TANF) and Supplemental Nutrition Assistance Program (SNAP), which have not been fully utilized in supporting Asian American children. Additionally, the study emphasizes the need for culturally tailored social work interventions that address these unique challenges. Findings reveal a critical gap in services and advocate for more culturally sensitive mental health programs and community outreach initiatives to improve resilience, academic performance, and social integration among these underserved children. This study concludes with policy recommendations aimed at enhancing the visibility and accessibility of support systems for Asian American families affected by incarceration.
Better Sexual Education Design for Children: Based on the Characteristics of Childrens Sexual Psychological Development
Authors: Hu Yueyang
Published: January 2025

To make children enter puberty with a healthy sexual mentality, it is very important to carry out pre-adolescent sex education that is corresponding to the characteristics of psychological development stages of children. However, there are no studies that specifically address the characteristics of children's psychosexual development, and few studies that explore how sex education can be targeted at each stage of a child's development. This paper intends to examine the traits of children's psychosexual development across various stages, utilizing Piagets and Eriksons developmental theories, summarize the findings, and explore how sex education resources should align with the developmental characteristics of children at different ages to enhance contemporary childhood sexuality education. This study conducts an unbiased and methodical analysis of the global literature from 19702024. The gaps and comprehensiveness of earlier studies are also assessed, and possible strategies for further strengthening child sex education are proposed based on the theories and techniques they provide. The research shows that Piaget's theory has a profound significance for studying the characteristics of sexual psychological development of preoperational children, and can be used as a reference for the design of gender identity curriculum. Erikson's theory is expected to be applied to the study of the psychological characteristics of social sexual interaction and the teaching design of children from 6 years old to pre-adolescence.
The Impact of The Critical Period Hypothesis Within Age Factors on the Learning Ability of SLA
Authors: Meng Siyuan
Published: January 2025

With the accelerated development of globalization, second language acquisition (SLA) has become a crucial issue in the study of language education research. In the recent years, the impact of individual difference on the SLA process has been a matter of great concern, including age, sex, character, cognitive style, study motivation, affective factor and so on. All these factors can influence the learners choices of language study tactics and their study effectiveness. The article summarizes research results on the influence of age on SLA learning ability, discuss the critical period hypothesis and relevant controversial views in depth, in order to provide theoretical support and direction guidance for future research. All in all, Despite the existence of different views and disputes, the CPH proposed by Penfield and Roberts and Lenneberg's subsequent research, to a certain extent, all offer important insights and thinking on understanding the influence of age on SLA. Educators can tailor their teaching base on learners age and needs, with a focused approach to promoting effective learning language.
A Higher Purpose: Conceptualizing the Role of Religion in Driving Social Innovation
Authors: Zhu Yujia
Published: January 2025

This study analyzes the function of religion as a catalyst for social innovation, highlighting how ethical frameworks and spiritual impulses embedded in diverse religious traditions propel societal progress. This study examines the impact of religious social capital on entrepreneurial activities, emphasizing how cohesive religious groups promote social entrepreneurship and sustainable development. The research conducts a conceptual examination of religious ethics, including compassion, justice, and communal duty, to elucidate how faith-based principles foster altruism and resilience in social entrepreneurs. The report also examines existing literature to evaluate the shortcomings in current research, including the absence of a complete framework that incorporates many religious viewpoints on social innovation. The research presents a conceptual framework demonstrating how religious beliefs influence ethical decision-making, foster community involvement, and augment intrinsic drive, so strengthening social innovation. These observations highlight the significance of integrating religious ideas as essential resources for ethical and sustainable societal advancement, promoting a cooperative strategy between faith-based and secular groups in tackling intricate global issues.
The Role of AI in Achieving Inclusive Education
Authors: Yang Siqi
Published: January 2025

Sustainable Development Goal (SDGs) 4 emphasizes inclusive education as one of the key objectives of experimenting with equity in education. The current convergence between education and developing technologies has led to the widespread use of artificial intelligence (AI) as a pedagogical tool in education. However, there is a lack of research on the relationship between inclusive education and artificial intelligence (AI) as part of the educational field. Therefore the main purpose of this paper is to explore how artificial intelligence (AI) can help to realize inclusive education. Through literature analysis, it is shown that artificial intelligence (AI) can increase students' accessibility, allow more and more disabled students to participate in the classroom, and artificial intelligence (AI) assistive technology can meet the different needs of disabled students. In addition, artificial intelligence (AI) can personalize learning for students with disabilities, improving their grades and performance. But further development of more comprehensive technologies and training of teachers is still needed in the future. Overall, artificial intelligence (AI) has played a positive role in achieving inclusive education.
Development and Treatment of Specific Dermatitis Vaccine
Authors: Zhu Zimeng
Published: January 2025

Specific dermatitis (SD), notably atopic dermatitis (AD), represents a prevalent group of chronic inflammatory skin diseases characterized by persistent itching, redness, and scaling, which impair daily activities and diminish quality of life. This review examines the mechanisms and clinical applications of biologic therapies targeting interleukins IL-4 and IL-13, central to ADs inflammatory response. Recent studies on tralokinumab and dupilumab, two monoclonal antibodies, demonstrate marked improvements in the Eczema Area and Severity Index (EASI) and Investigator's Global Assessment (IGA) scores, reflecting reduced inflammation and symptom severity. Despite promising clinical outcomes, challenges remain in treatment frequency, high costs, and limited accessibility, especially in lower-income areas. Future directions include developing therapeutic vaccines to achieve durable immune modulation, reducing reliance on biweekly injections, and exploring biosimilars to enhance global accessibility. A comprehensive, integrative approach addressing dermatological, immunological, and psychological aspects will be crucial for advancing personalized AD management and improving patient outcomes.
Applications of CP-31398 Targeting P53 on Cancers
Authors: Cai Xintong
Published: January 2025

Among the world's biggest causes of death is cancer. DNA damage is prevented by P53, a transcriptional factor that is encoded by the TP53 gene. A TP53 mutation was found in more than 50% of human cancers. In cancer cell lines with mutant or wild-type p53, CP-31398 has been used to stabilize the active state of p53 and increase p53 activity. Nonetheless, several issues persist, including deficiencies that directly impact the ensuing gene development and the absence of p53 selectivity. In vitro, CP-31398 demonstrates its anti-cancer properties by successfully stabilizing the DNA core domain of the tumor suppressor protein p53. According to the present study, CP-31398 saved the mutant p53 protein's transcriptional activation function by restoring the ability of mice and human tissue culture cells to bind DNA. Future research is thus necessary to fully assess CP-31398's potential. CP-31398 does not, it has been shown in some research, stabilize p53. The DNA-p53 core domain complex has also been seen to be altered and harmed by CP-31398, which is contained in DNA. Moreover, CP-31398 decreased both the His 273 mutant and wild-type p53's sequence-specific DNA binding. CP-3138's therapeutic potential has been shown in a number of in vitro and in vivo cancer models, such as hepatocellular carcinoma (HCC), colorectal cancer, pancreatic cancer, breast cancer, bladder cancer, neck squamous cell carcinoma, etc. In order to facilitate the applications of CP-31398, more research is still needed to comprehend the mechanism of CP-31398 in malignancies.
Human Papillomavirus (HPV) infections and cervical cancer: causes, diagnosis and treatment
Authors: Yan Sixun
Published: January 2025

HPV infections have become the main culprit of thousands of deaths by triggering the development of cervical cancer (approximately 620,000 female cases in 2019, according to the data provided by WHO) due to the oncoproteins E6 and E7 expressed by the high-risk HPV types (for example HPV 16 & 18). To reduce the impact brought, other than physical prevention, three types of prophylactic vaccines- the bivalent vaccine (Ceravix), the Gardasil 4 vaccine, and the newest Gardasil 9 vaccine, were developed for available uses. Diagnosis and screening processes including both molecular diagnosis (DNA & RNA-based diagnosis), and physical diagnosis (including HC2, Cobas, and HR HPV test) are done by patients around the globe in a more common way to eliminate the possibility of delaying treatments (involving cryotherapy and using salicylic acid for treating HPV warts, and cervical cancer treatments including hysterectomy, radiotherapy, and chemotherapy for different stages) until the illness has entered the CIN3 phase. This thesis will focus on the causes, diagnosis methods, current treatments, and possible treatments, of HPV infections and HPV-triggered cervical cancer.
Measuring Regional Green Finance Development Level in China
Authors: Wang Jiali
Published: January 2025

Green finance, defined as supporting the development of green and low-carbon projects, serves as a mechanism for tackling resource shortages and environmental damage caused by Chinese economic reform and opening up. The reason for studying Chinese green finance development path by region is that each region has different economic development policies, investment in education and environment, and investment in scientific and technological innovation. This article employed the entropy method and DEA-Malmquist model to measure the efficiency of Chinese green finance development. The entropy method assigned values to each green financial development efficiency evaluation indicator and determined the weight. Then the DEA-Malmquist method was conducted to calculate the weight of each indicator to measure the dynamic development scale and efficiency. Based on the above research results, three policy recommendations are put forward to improve economic development, enhance innovation capabilities, and improve the green financial system.
The Impact of Advertising Marketing on Pepsi Sales
Authors: Guan Hebin
Published: January 2025

PesiCo has long been considered as one of the worlds leading beverage company. It has constantly changed its marketing strategy to maintain its competitiveness in the market. Their product Pepsi can be demonstrated as a suitable example. This study aims to determine how advertising marketing can influence Pepsis sales. Based on a review of the literature on advertising marketing theory and the relationship between advertising marketing and sales, secondary data was used to indicate the results. Analysis of the data demonstrated that these marketing strategies have significantly increased Pepsis sales and strengthened its competitiveness in the market. The results indicate that proper use of advertising marketing does have a positive impact on sales. On this basis, it is recommended that other businesses can use advertising marketing in their selling process. Further research is needed to use more primary data to support the results.
Application of Lagrange Multipliers in One-period Portfolio Model When Incorporating Non-linear Utility Functions
Authors: Jiang Yuqiao
Published: January 2025

This paper explores the extension of the traditional one-period portfolio optimization model through the application of Lagrange multipliers under non-linear utility functions. Classical portfolio theory typically assumes linear or quadratic utility functions, simplifying the relationship between risk and return. However, real-world investor preferences often exhibit more complex, non-linear behaviors, especially in the presence of risk aversion or behavioral biases. By incorporating non-linear utility functions, this study examines how the role of Lagrange multipliers evolves when managing the trade-off between maximizing expected utility and adhering to budget constraints. Through a modified Lagrangian approach, it derives new first-order conditions and analyze the resulting changes in optimal portfolio allocation. The analysis focuses on how non-linearity in utility functions alters the sensitivity of portfolio weights to changes in asset prices and risk-free rates. Additionally, this paper highlights the implications of this extension for practical portfolio management, particularly in cases where investor utility is driven by non-standard risk preferences. The findings contribute to a deeper understanding of how portfolio optimization models can be tailored to better reflect real-life decision-making scenarios.
Bitcoin's Risk-Return Pattern: A Comparative Analysis with Traditional Assets
Authors: Zhou Junyi
Published: January 2025

Bitcoin (BTC) is known for its exceptional return potential, but this comes with high volatility which makes it a high-risk, high-reward investment. This paper examines Bitcoin's risk-return pattern compared to traditional assets (DXY, GLD, SPY and QQQ). We apply key indicators such as annualized return, volatility, sharp ratio, skewness, and kurtosis to explore the return and risk of Bitcoin. We find that Bitcoin has higher annualized return compared to traditional investment assets, but with much higher volatility and maximum drawdown. In addition, we combine Bitcoin with traditional assets with different proportions to construct investment portfolios. The results show that the sharp ratio increases to a maximum with low percentage of Bitcoin in the portfolio and then start to decrease. In order to further explore Bitcoins risk-return pattern, we analyze several famous cryptocurrency risk events in history and reveal the vulnerabilities in the cryptocurrency ecosystem. Our analysis is crucial to investors who seek to balance the attractiveness of Bitcoin's high returns with its inherent volatility.
The Impact of ESG Disclosure on Financial Performance in Oil and Gas Companies: A Difference-in-Differences Analysis
Authors: Guo Yuanjie
Published: January 2025

With increasing global attention on sustainable development and corporate social responsibility, more and more countries and regions are requiring companies to disclose information related to environmental, social, and corporate governance (ESG). Especially in the oil and gas industry, ESG information disclosure has become an important means of measuring corporate governance and sustainable development performance. However, there is still controversy in both academic and practical circles regarding whether ESG disclosure can improve financial performance and its impact on companies fulfilling their fiduciary responsibilities. Therefore, this study aims to explore the impact of ESG disclosure on the financial performance of companies in the oil and gas industry, and analyze its relationship with the fulfillment of trust responsibilities.This study adopts the Difference in Differences (DID) method and selects oil and gas companies affected by ESG disclosure policies as research objects. By comparing the changes in financial performance of these companies before and after policy implementation, the role of ESG information disclosure in improving company transparency and reducing information asymmetry is analyzed. In addition, this study also explored the interactive relationship between ESG disclosure and trust responsibility under different legal frameworks, especially in the application of high environmental risk industries. The research results indicate that active ESG disclosure not only helps improve the long-term financial stability of companies, but also enhances shareholder trust and reduces legal risks, especially in regions with sound policies where the effect is more significant. However, research has also found that ESG disclosure may increase short-term costs and conflict with short-term financial goals in trust obligations.
Research on the Sustainable Development Assessment System of Chinese Logistics Enterprises in the Context of Digital Intelligence and Dual Carbon Era
Authors: Zhang Yitong
Published: January 2025

China has entered a "new normal" characterized by high-quality development driven by digital intelligence. The 2024 Government Work Report emphasizes that the logistics industry is gradually forming a new green logistics ecosystem through technological innovation and industrial restructuring, laying the groundwork for a green, low-carbon supply chain. The role of national logistics hubs in urban logistics aggregation and radiation is continuously enhancing. However, logistics enterprises remain at the initial stage of environmentally sustainable development. Therefore, it is essential and practically significant to construct a sustainable development assessment system under the context of digital intelligence and dual carbon goals. This study focuses on the construction of a logistics assessment index system, utilizing the Triple Bottom Line (TBL) principle to conduct a comprehensive analysis of logistics processes from social, economic, and environmental dimensions. It investigates green management strategies for enterprises and proposes actionable suggestions to address issues related to an excessive focus on short-term financial targets and an incomplete performance evaluation index system. This framework aims to adapt to the demands of intelligent and flexible upgrades, thereby promoting the long-term sustainable development of logistics enterprises.
Investigating the Effectiveness of Management Trainee Programs in the Fast-Moving Consumer Goods Industry in China
Authors: Yuan Yajun
Published: January 2025

The research examines the factors influencing the overall effectiveness of management trainee (MT) programs in the career progress of trainees and evaluates the suitability of MT programs for small and medium-sized enterprises (SMEs) within the Fast-Moving Consumer Goods (FMCG) industry in China. The study identifies perceived leadership training, perceived mentor support and perceived job rotation as the key variables affecting overall program effectiveness. Using a sample of 400 FMCG employees who have participated in MT programs and data collected via online questionnaires, the study conducted a comprehensive analysis employing correlation and regression techniques to determine the significance and impact of the key variables. The results revealed that, perceived leadership training, perceived mentors support and perceived job rotation all have positive and significant impacts on overall program effectiveness. Furthermore, the positive coefficient levels and strong statistical significance indicated that, the key variables, considerably enhances career progression of trainees and also make MT programs suitable and beneficial for SMEs in the Chinese FMCG industry.
The Impact of AI on Labor Market and the Corresponding Countermeasures
Authors: Sun Ziqing
Published: January 2025

Artificial intelligence (AI) has developed rapidly in recent years, bringing significant convenience to both economic and social life. AI has greatly improved labor productivity and promoted national economic growth. But at the same time, it also brought about significant changes in production and lifestyle. It has shown the most significant influences in the labor market, where the employment structure and income levels in many industries are undergoing significant changes. However, an issue that cannot be overlooked is the substantial impact AI has had on the traditional human resource market and employment models. This paper analyzes the effects of AI on the labor market, focusing on changes in employment trends, structures, unemployment, and income inequality. The study also examines the dual nature of AI and its impact on the labor market in both the short and long term, offering several policy recommendations to mitigate its negative effects. This research provides theoretical and practical insights for labor market studies towards the AI technology.