bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluación del uso de suero autólogo como tratamiento de ulcera corneal en conejos
Authors: Sarmiento Milton Gustavo , Rubio-Arias Pablo Giovanny
Published: May 2024

Las ulceras corneales son alteraciones frecuentes en oftalmología veterinaria, como resultado de diferentes etiologías que desencadenan graves secuelas derivadas al epitelio corneal pudiendo producir una pérdida importante de la visión debido a la opacificación cicatricial y astigmatismo sequerales. El objetivo de la presente investigación evaluar el efecto terapéutico del suero autólogo mediante la preparación y manejo de la terapia en la práctica oftalmológica en conejos. La metodología consistió en utilizar 10 conejos los cuales fueron valorados el grado de ulceración bilateral (superficiales o profundos), posterior se realizó la extracción de sangre y la preparación del suero aplicando dos gotas de suero en el ojo derecho con intervalos de 8 horas por 7 días consecutivos, en el ojo izquierdo se aplicó el grupo control con aplicación de  suero fisiológico, posterior los animales fueron sacrificados y los ojos fueron evaluados por los efectos observados clínicamente en la superficie ocular y córnea y por análisis histopatológico. Los resultados indicaron que fue menor el porcentaje de ojos tratados con suero autólogo con signos de inflamación, fibrosis, fibroblastos, neovascularización y epitelización, fueron menores que los ojos que no recibieron ese tratamiento. Sugiriendo que podría ser efectivo emplear el suero autólogo en para tratar las ulceras corneales, sin embargo, las diferencias no fueron significativas estadísticamente. Se concluye que es necesario evaluar la efectividad del suero autólogo bajo otros protocolos de aplicación con menor tiempo entre aplicaciones o tratamientos con más días, dado que la investigación sugiere que podría ser útil para tratar esta patología.
Serving to Learn: Increasing Agriculture Students Self-Efficacy Through Service-Learning
Authors: McKibben Jason , Hyjeck Amanda , Clemons Chris , Hancock Garrett , Yopp Ashley
Published: May 2024

Service learning is a form of experiential learning that helps students be able to both apply concepts and provide a benefit to an organization, individual, or group other than the learner. The lack of efficacy of our students with the complex skills learned in many agriculture courses brings about a sense of fear and trepidation in students that can cause them to either not engage with the material/skill or do so in an ineffective manner. Service learning was used in a course that has had low levels of efficacy associated to help motivate students to learn and practice the skills being taught. Students in an agricultural mechanics course engaging in activities with Habitat for Humanity progressed through Bandura’s four types of learning experiences integral to the efficacious establishment of a behavior in two directions. Using Constant Comparative method to analyze the reflections of the students it was determined that they progressed through the activity from the perspective of students, moving from the least to most efficacious. They then, with no prompting, reflected backwards from the perspective of most to least efficacious as they began to reflect on how they would facilitate communicating or teaching these same concepts to novices.
Peran Kepolisian dalam Penanggulangan Pelanggaran Lalu Lintas oleh Anak sebagai Pengendara Sepeda Motor di Wilayah Polresta Banda Aceh
Authors: Charisa Amelia
Published: May 2024

Perkembangan zaman, maka meningkat pula segala kegiatan manusia untuk memenuhi kebutuhan dan keperluannya. Salah satu diantaranya adalah kebutuhan angkutan atau alat transportasi, khususnya jalan raya. Lalu lintas dan angkutan jalan mempunyai peran strategis dalam mendukung pembangunan dan sebagai bagian dari upaya memajukan kesejahteraan umum sebagaimana diamanatkan oleh UUD 1945. Bagaimana peran kepolisian dalam penanggulangan pelanggaran lalu lintas oleh anak sebagai pengendara sepeda motor, Bagaimana hambatan dan upaya yang dihadapi kepolisian dalam penanggulangan pelanggaran lalu lintas yang dilakukan oleh seorang anak sebagai pengendara sepeda motor.
Penelitian ini bersifat deskriptif analisis dan menggunakan pendekatan yuridis emperis dan sosiologis. Data diperoleh data primer (Field Research) dan data sekunder (Library Research). 
Bedasarkan hasil penelitian lapangan diperoleh data bahwa penanggulangan pelanggaran lalu lintas yang dilakukan oleh anak di bawah umur sebagai pengendara sepeda motor, Kepolisian Satuan Lalu Lintas Polresta Banda Aceh dalam menjalankan peran dan tugasnya melakukan upaya penanggulangan dengan tindakan berupa :  himbauan dan sosialisasi kepada masyarakat dan orang tua agar terus mengawasi anak-anaknya agar tidak mengendarai kendaraan bermotor, melakukan penyuluhan ke sekolah-sekolah, serta memberikan nasehat dan teguran, dan dilakukan dengan melakukan pemberian peringatan langsung terhadap anak-anak yang melakukan pelanggaran lalu lintas, selanjutnya dilakukan penilangan.
Perdebatan Para Mujtahid Tentang Teori Mashlahah Mursalah
Authors: Aminudin Aminudin , Panjaitan Budi Sastra , Lubis Fauziah
Published: May 2024

Artikel ini membahas tentang perdebatan para Mujtahid tentang teori maslahah-mursalah, Mayoritas ulama menerima qiyas sebagai sumber hukum Islam yang keempat setelah al-Qur’an, as-Sunnah dan ijma’ para sahabat. Sedangkan metode istinbath hukum yang lainnya, termasuk maslahah-mursalah atau istishlah yang diperkenalkan oleh Imam Malik selalu diperdebatkan, bahkan ditolak oleh mayoritas penganut mazhab asy-Syafi’iyah. Penelitian ini bersifat normatif atau penelitian kepustakaan, yaitu dilakukannya penelitian dengan meninjau bahan pustaka untuk mengetahui bagaimana pendapat para mujtahid tentang teori maslahah mursalah. Hasil dari penelitian ini menurut Jumhur ulama berpendapat bahwa maslahah mursalah hujjah syara’ yang dipakai sebagai landasan penetapan hukum. Karena kejadian tersebut tidak ada hukumnya dalam nash, hadist, ijma’ dan qiyas. Maka dengan ini maslahah mursalah ditetapkan sebagai hukum yang dituntut untuk kemaslahatan umum.
The prevalence of neck pain, back pain and low back pain among third-year medical students at universities in the metropolitan region of Porto Alegre in times of Covid-19
Authors: Pena Della Mea Vivian , De Oliveira Carolaine , Teodoro Ezequiel Guerra Marcelo , Roberto Galia Carlos , Almeida Samantha
Published: May 2024

Objective: To determine the prevalence of cervical, dorsal and lumbar pain caused by switching to remote classes during the Covid-19 pandemic. Methods: This is an original article based on a cross-sectional study among men and women over the age of 18 who are third-year medical students to assess the incidence of neck pain, back pain and low back pain, using online forms with questions about physical and mental health. Results: Around 60% of the participants said they had adapted their study environment because of the remote classes, with a further 70% saying they were attending classes in the office, with their backs poorly supported. In addition, there was a low number of overweight students who performed daily stretching. Conclusion: The data was analyzed using tables, descriptive statistics and the statistical test: Mann-Whitney Non-parametric Test and Krsukal-Wallis Non-parametric Test and the importance of further research was highlighted, given that this research topic is essential for the prevention of possible comorbidities.
Acute viral bronchiolitis in infants: A narrative literature review
Authors: Smidt Costa Juliana , De Sousa Pinheiro Barbosa João , Fernandes Feitosa Braga Victor , Flávia Moura Marques Ana , Magalhães Zendersky Fernanda , Da Costa Luiz Bonelly Beatriz , Abe Rodrigues de Melo Giovanna , Henrique Soares Campelo Vitor , De Almeida Cunha Isabella
Published: May 2024

Severe acute bronchiolitis is mostly caused by the respiratory syncytial virus (RSV) and is the main cause of hospitalization in children under one year old. Although it has a low mortality rate, it has a high morbidity rate, requiring early diagnosis through a detailed clinical history and physical examination. A narrative review of fourteen articles found in the PubMED/MEDLINE, SciELO and BVS electronic databases was therefore carried out, with the aim of reviewing the most up-to-date literature on the subject. Currently, the monoclonal antibody Palivizumab is the main agent used to prevent bronchiolitis and is available for patients at high risk of developing the serious disease. In addition, the Abryso vaccine was recently approved by the National Health Surveillance Agency (Anvisa) and will be administered to pregnant women in the last trimester of pregnancy, with the aim of preventing the disease in newborns. Finally, it was found that the appropriate management of acute viral bronchiolitis consists of supportive measures such as hydration, nutritional support and oxygenation when necessary, while the use of corticosteroids and bronchodilators has not been shown to reduce the length of hospital stay or the natural course of the disease.
Green areas in cities mitigate cases of obesity: Case study from Espírito Santo do Pinhal-SP
Authors: Gabrielly Barroso Samantha , Maria Ribeiro Emily , Rafael Martins Mariana , Victor dos Santos Yuri , Vitor Pereira João , Eduardo Alexandre Vicente Carlos , Martelli Anderson
Published: May 2024

Obesity has been treated as a worldwide epidemic, and the number of obese people in Brazilian cities is growing. In most cases, obesity is related to eating high-calorie foods and a lack of physical activity. Thus, the aim of this study was to portray how green areas in the municipality of Espirito Santo do Pinhal-SP help to reduce numerous diseases, including obesity, which is characterized as a public health problem. A survey of areas in the municipality was carried out, looking at the existence of outdoor gyms, tree vegetation and structures for practicing physical activities. During the survey, five green areas used by the population for physical activity were inspected, and it was observed that the places that had walking trails, courts and outdoor gyms were more frequented by the population than the places that only had outdoor gyms. Thus, green areas have a positive impact on people's lives, encouraging physical activity and greater social interaction, as well as reducing cases of obesity and other cardiovascular comorbidities.
Unique therapeutic project reinforcening the importance of the bond between doctor and patient for adherence to the treatment of chronic diseases: Experience report from medicine students
Authors: Mussi Manuela , Quagliato Quibao Leonardo , Mazza da Silva Galvani Naiani , Tajara Pasquini Tiago , Bernardes Yasmin , Henrique Fernandes de Lima Pedro , Prado Bereta Vilela Renata
Published: May 2024

The population is not limited to the expressions of the illnesses they have. Some obstacles, such as low adherence to treatment, refractory patients, users' dependence on the health service, among others, highlight the complexity of the subjects who use health services and the limits of clinical practice centered on the disease¹. It is well known that the doctor-patient relationship is a fundamental factor for adherence to treatment, always aiming for the best result to improve the quality of life for individuals and the whole community. This relationship is a topic that is currently finding renewed interest in scientific production, training and clinical practice, with the application of communication techniques that can provide better quality care and treatment².
Palliative care at the end of life and the role of the psychologist
Authors: Covalciuk Viviane
Published: May 2024

Mallampati, Orotracheal intubation, Modifications.Palliative care (PC) is defined as care for patients diagnosed with progressive, incurable and/or chronic-degenerative diseases, and can cover any life-threatening illness that culminates in finitude. Therefore, PC aims to ease the pain and relieve the suffering of invasive treatments by providing dignity, comfort and welcome to improve the quality of life of patients diagnosed with incurable diseases; this care can also include the individual's family members and caregivers, providing them with welcome, assistance and support to deal with the issues arising from the progression of the disease. Thus, the aim of this study is to describe the participation of the multi-professional team in PC, the patient and their family, i.e. all those involved in this process of becoming ill until the end of life, and in particular to investigate how psychology works in caring for the patient, the family/caregiver and the healthcare team. This study used the literature review method. This bibliographic review selected 27 scientific articles, 02 books, 01 Resolution of the Federal Council of Psychology, 01 Manual of Palliative Care of the National Academy of Palliative Care, 01 Manual of Palliative Care of the Sírio Libanês Hospital, 01 Primer of the Brazilian Society of Geriatrics and Gerontology, 01 thesis. It will record how the patient copes during the journey from the diagnosis of illness to the end of life, as well as the participation and experience of the family, the multi-professional team and in particular the participation of Psychology within this scenario, as it is the scientific field that covers the holistic sphere of the individual, and its premise is to deal with issues involving human relationships, bringing the necessary comfort in the face of this new context of an established disease that will cause the end of existence. In this way, the psychologist is the professional trained to study mental processes, such as feelings, thoughts, behaviors, understanding their subjectivity and, in this context, helping the individual to understand their self in the face of the serious and irreversible clinical state that precedes the proximity of death, resolving outstanding issues with themselves and their families, providing support so that everyone can be at peace at the moment of farewell. Finally, it will discuss the importance of humanized care in PC through the inclusion of a specific subject in the undergraduate courses of health professionals, paying special attention to the field of psychological knowledge since it is the professional who is the protagonist in this scenario.
Hyper IgE syndrom suspect - Case Report
Authors: Igor Albanaz Vargas Marcos , Albanaz Vargas Lucas , Muccini de Carvalho Cavalcanti Fernandes Giuseppe , Alves de Lima Junior Eunilson
Published: May 2024

Introduction: Hyper IgE syndrome (HIES) is a rare condition of the immune system characterized by various types of infections throughout life. This syndrome can be divided into two types, dominant heterozygous related to STAT3 gene mutation and recessive homozygous, which can also be subdivided into two groups related to Tyk2 and DOCK8 gene mutations, each presenting variations in their clinical presentations. Diagnosis is based on genetic sequencing, although there are some symptoms, clinical factors, and hereditary factors that can assist in diagnosis. There is no specific treatment for this pathology, with the main focus being on controlling infections and infusing immunological therapies such as intravenous immunoglobulin G.
Use of tie-in femur osteosynthesis in free-living aracuã scamoso (ortalis squamata) with blockage of the femoral and ischiatic nerves
Authors: Boscato Garcia Leila , Flores Moraes Lilian , Paula Morel Ana , Depelegrin Carolina , Favreto Isadora , Ribeiro dos Santos Vinícius
Published: May 2024

We report the case of an adult scaly-breasted arachnid, which arrived for treatment with a history of being on the ground in the courtyard of a house, unable to stay in a station. On clinical examination, the bird had an immobile right femur, with a probable comminuted fracture, and the decision was made to perform a surgical procedure to correct the fracture. The treatment used the tie-in technique, where a 1.2 mm intramedullary pin was placed in the femur for initial alignment of the bone fragments, while external fixation was carried out with three pins of the same thickness as the previous one, two in the cranial region and one in the region distal to the fracture site. Two months after the surgery, an X-ray was taken to check for the formation of bone callus, with a satisfactory result. The external fixator was removed the following day, and seven days after removal the bird was discharged and released. As well as the tie-in technique having a high success rate with a complete return of function, it has the advantage that its implants are removable, which is important when the animal is returned to the wild, preventing these implants from remaining in the environment if it dies.
Entrepreneurship and innovation - Feasibility study on sustainable residential food production through Aquaponics
Authors: Madureira Garcia Fábio , Pedro Gonzalez Junior Ivo , Batista de Jesus Bertolini Edinilsa , Manuelle Sarges Costa Elaíne
Published: May 2024

The complexity of today's reality drives the insertion of new ideas into the educational context, with empowering projects that impact social, economic and environmental systems, generating sustainable opportunities. Entrepreneurship in higher education institutions in Brazil requires innovative approaches, beyond isolated disciplines, to promote a sustainable entrepreneurial culture and contribute to community development. Faced with social needs, questions arise about projects that promote individual and collective training, meeting demands for interprofessional training in the social, economic and environmental spheres.
Gestational syphilis: a socioeconomic analysis of the increase in rates in Brazil
Authors: Silva Valentini Alice , Carolina Dias Pereira Ana , Toller Silva de Noronha Luiza , Bernardes Rattis Batista Julia , Eduardo Chufalo José
Published: May 2024

Syphilis is a sexually transmitted infection (STI) that has been known since the 15th century. This pathology, whose etiological agent is Treponema Pallidum, can be classified as: acquired, gestational or congenital, since transmission can be sexual or vertical, from mother to fetus. In recent years, gestational syphilis has seen a progressive and considerable increase in the number of cases detected in Brazil. Thus, knowing that this disease puts not only the pregnant woman's life at risk, but also that of the fetus, which can acquire the infection via transplacental transmission, it is extremely important to understand the factors involved in the increase in the number of detected cases of gestational syphilis, which is the main objective of this research. From a socio-economic perspective, the article discusses the correlation between the increase in cases and social inequality factors in areas of Brazil, understanding how the particularities of each region are reflected in health management, based on the incidence of the disease. As a methodology, we plan to carry out a bibliographical review based on books and catalogued scientific articles published in online indexed databases, such as Scientific Library Online (SciElo) and Pubmed. In addition, an analysis of data from the DATASUS platform will be carried out, also from the 2010 Census. As expected results, we believe that the increase in the rate of gestational syphilis is closely related to socioeconomic factors and access to adequate prenatal care.
The limits and possibilities of music in the early years of elementary school
Authors: Fialho Gilmeire Gottardi Silva
Published: May 2024

In the context of curricular organization at the national level, there are several institutions that still find it difficult to integrate music teaching into the educational context, given its specificity. This article is an excerpt from a master's research in which a study was carried out on the pedagogical practice of teachers regarding music in Elementary School. The research field was a municipal school, located in the municipality of Goiânia, State of Goiás, the participating subjects were: 01manager, 14 (fourteen) teachers and 132 (one hundred and thirty-two) regularly enrolled students. This qualitative study had the data collected through a structured interview, after approval by the Ethics Committee of the Military Police College - FPM (CAAE: 61333922.4.0000.0145, Opinion No. 5.586.122) and the dissemination of the results was authorized by the research participants, who signed the Free and Informed Consent Form and the Informed Consent Form. It was found that most of the teachers did not have any discipline on Music in the initial training. The students signaled the reproduction of classes focused only on activities that involve the Visual Arts, data identified through the interviews carried out, a fact that contributes to the fragility in the initiatives of the Municipal Department of Education regarding the process of implementing the teaching of music in schools, given the inclusion of music as a proposed content for the teaching of this discipline.
Multi-objective optimization using evolutionary algorithms: An antifragile approach to portfolio selection
Authors: Gotardelo Davi Riani , Pereira Guilherme Costa Obeica
Published: May 2024

Considering the documented difficulties in empirically applying widely recognized portfolio selection models that use mean-variance relationships as central features, as proposed by Markowitz and later extended in CAPM by Sharpe, this study aims to extend these theories. Drawing upon contributions from Keating and Shadwick, which highlight CAPM's limitations in handling non-normal distributions, the study introduces non-convex attributes into a multi-objective optimization framework using evolutionary algorithms. Additionally, an antifragile metric known as CVIX is implemented to assess conditional correlation with the VIX, thereby addressing questions concerning the feasibility of market portfolios outperforming CAPM's theoretical market portfolio. Optimizations were carried out on U.S. markets, using time frames from 1994 to 2022. The results are encouraging; in contrast to optimizations that employed solely convex attributes, which yielded inferior outcomes in all scenarios compared to the OCAPM model, applying the antifragile metric along with non-convex attributes in multi-objective optimization produced superior results.
The Challenges and Opportunities of Post-COVID Situation for Small and Medium Enterprises (SMEs) in Bangladesh
Authors: Bhuiyan Mohammad Rakibul
Published: May 2024

Similar to the rest of the world, Bangladesh has been affected by the current and ongoing pandemic COVID-19 crisis. Small and medium enterprises (SMEs) are the fundamental economic pillar for business development in Bangladesh. The main purpose of the research paper is to determine the post-COVID challenges and opportunities on SMEs in Bangladesh. Before staring the pandemic situation, the main barriers to the establishment of SMEs included access to formal credit, a lack of qualified labor, high operational costs, poor product quality, a lack of financial literacy, etc. SMEs are experiencing a capital constraint, increased operating costs, and employee layoffs as a result of this global epidemic. Both primary and secondary data are conducted to identify the findings of the study. Statistical analysis has been conducted by using the Microsoft Excel software. Sample size is 300 respondents from the study area (Dhaka and Narsingdi District) in Bangladesh. The findings of the study are that 52% of businesses have completely shut down its operation because of COVID-19. Moreover, 78% people in Bangladesh enable to run business activities on online platform that is possible only for COVID-19 problems, otherwise, people are unwilling to accept technology. To keep SMEs in business, emphasis must be placed on using government stimulus monies properly. Moreover, the real possibilities and opportunities of Bangladesh remain in the SMEs and therefore the sector should get more concentrating on the sustainable growth and development of the country through overcoming the pandemic COVID-19.
Implementasi pendidikan karakter berbasis Pesantren pada siswa-siswi program keagamaan di Madrasah Aliyah Sunan Pandanaran Sleman
Authors: Rohili Ili , Najib Khotim Hanifudin , Fitriyah Eka Laila , Alfina Alisa
Published: May 2024

Purpose: This study discusses the planning, implementation, and evaluation of the implementation of boarding-based education on Sunan Pandanaran Aliyah Madrasah religious program students and how the results helped by considering the implementation of this pesantren-based character education.
Method: This research is a field research, the data collection tools used are observation, interviews, and documentation. The research subjects were students of Sunan Pandanaran Aliyah Madrasah. This study discusses qualitative descriptive, namely research that discusses what phenomena are discussed by research in this case the students of Sunan Pandanaran Aliyah Madrasah in the implementation of boarding-based character education.
Findings: The results of this study indicate that (a) pesantren-based character education planning is well integrated with the madrasah vision and mission announced on all subjects and the purpose of developing affective / physical aspects both spiritual and social. (b) Implementation of pesantren-based character education integrates character education in all subjects, according to the RPP made by each subject teacher, then the character education requested through explanations, providers of examples and challenges to facing challenges, habituation to noble behavior is done every day, and teachers and boarders provide good role models.
La inimputabilidad en menores infractores y la apremiante reestructuración de la edad penal en el Ecuador
Authors: Cabezas Ruiz Freddy Leonardo , Jácome Malusín Elizabeth Monserrath
Published: May 2024

El objetivo del presente artículo gira en torno al evidente aumento de casos de adolescentes infractores en los últimos años y la notable urgencia de reducir la edad de la responsabilidad penal a partir de los dieciséis años. Se estudia los medios de aplicación dentro de la normativa vigente en la legislación ecuatoriana y la apremiante necesidad de adoptar medidas al asociarse la delincuencia organizada con menores. La metodología que se utilizó en la presente investigación es de carácter cuantitativo, puesto que, compone datos descriptivos con la recopilación de información, revisión de la normativa vigente, bibliográfica etc. por añadidura se utilizó el método inductivo y deductivo, por cuanto se desarrolla en la observación de los hechos que son de utilidad para el lector y el investigador en consecuencia, obtener una generalización de toda la información, de la misma forma, se usa el procedimiento analítico – sintético, puesto que se descomprime todos los datos recopilados cautelosamente para comprender cuál es la causa y efecto del fenómeno trabajado, razonablemente, al juntar toda la información, se concluye en, cómo la delincuencia organizada ha tenido un gran efecto en los menores y la grave necesidad de reformar los artículos 305 y 330 del Código de la Niñez y la Adolescencia.
Assessment of Repeated Electrocardiogram Findings in Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19
Authors: Yakut Kahraman , Ozyilmaz Isa , Yakut Nurhayat , Bekece Esma , Ceylan Berna , Toprak Muhammet Hamza Halil , Sahin Gulhan Tunca , Cansaran Tanıdır Ibrahim , Öztürk Erkut
Published: May 2024

Background: Cardiac involvement, stemming from the novel multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease-2019 (COVID-19), leads to common and severe complications. Objectives: The aim of this study is to compare and evaluate repetitive electrocardiogram (ECG) results and laboratory indicators in children diagnosed with MIS-C upon their initial hospital admission. Methods: This prospective, single-center study, conducted between December 2020 and October 2022, included repeated electrocardiographic and laboratory tests. Changes in the ECG over the course of the disease were regularly recorded for three months. Results: This study included 72 patients, 25 of whom were female. Mitral regurgitation and left ventricular systolic dysfunction were observed in 25% of the patients. Statistically significant differences (P < 0.05) were detected among the serial measurements of absolute neutrophil-lymphocyte count, CRP, procalcitonin, ESR, D-dimer, troponin T, pro-BNP, ferritin, and interleukin-6. Significant differences were also observed in heart rate, PR interval, QRS duration, QT duration, Fredericia QTc, JT interval, presence of sinus tachycardia, presence of first-degree AV block, presence of wide QRS, abnormal QRS axis, abnormal T axis, long QTc, and ST-T changes (P < 0.05). Additionally, significant differences were noted in the absolute lymphocyte count, troponin levels, and ferritin levels between patients with prolonged abnormal ECG findings and those whose ECG findings were normal or had returned to normal. Furthermore, statistically significant differences were observed in absolute lymphocyte count, ferritin, and fibrinogen levels among the other four groups (P < 0.05). Conclusions: Electrocardiogram findings in patients measured serially appear to improve over time. Since patients with MIS-C may experience ECG abnormalities that could lead to arrhythmias, close monitoring and the establishment of standardized approaches are essential. Long-term ECG abnormalities were associated with a decrease in absolute lymphocyte count and elevated levels of troponin, ferritin, and fibrinogen.
Essential Oil of Hymenocrater longiflorus Benth. as a Pro-Apoptotic Agent in Human Breast Cancer Cells
Authors: Mohammadi Karasi Pashiv , Shakeri Raheleh , Safavi Maliheh , Khorshidi Jalal , Chinjoo Negin
Published: May 2024

Background: Breast cancer is one of the most common cancers in women. Current treatments, such as chemotherapy and radiation therapy, often involve numerous side effects. Consequently, it is essential to discover new anticancer compounds that are safer and more effective. Objectives: The aim of this research is to investigate the anticancer effects of Hymenocrater longiflorus Benth. essential oil. Methods: The anticancer properties of H. longiflorus Benth. essential oil were investigated on MDA-MB-231 and MCF-7 breast cancer cells using MTT assay, double staining with acridine orange/ethidium bromide, and flow cytometry. The essential oil of H. longiflorus Benth. was analyzed using gas chromatography-mass spectrometry (GC-MS). Results: The essential oil significantly reduced the viability of breast cancer cells depending on the concentration (dose) and duration. Results from double fluorescent staining and flow cytometric analysis also indicated that apoptosis is the primary mechanism of cell death. Non-targeted GC-MS metabolomic data analysis of the essential oil revealed the presence of various anticancer compounds, including α-pinene, linalool, and caryophyllene, in the essential oil. Conclusions: In conclusion, the essential oil of H. longiflorus Benth. is a promising source of anticancer metabolites that can be further evaluated for drug therapy or as a co-treatment with conventional chemotherapeutic agents.
Impact of Ultrafiltration Profiling Compared to Conventional Methods on Blood Pressure Regulation Among Hemodialysis Patients
Authors: Haghighi Enayat Morteza , Azami Hiva , Tapak Leili , Borzou Seyed Reza , Gholyaf Mahmood
Published: May 2024

Background: Standard hemodialysis sessions pose challenges for patients due to fluctuations in blood pressure. Alternative strategies, such as ultrafiltration profiling, have been proposed as potentially more effective treatments. Objectives: This study aimed to evaluate the effects of ultrafiltration profiling compared to the conventional method on blood pressure regulation among hemodialysis patients. Methods: This study employed a pre-test and post-test design, involving a single group of 30 hemodialysis patients undergoing treatment at Shahid Beheshti Hospital in Hamadan in 2022. The sampling method used was simple random sampling. The intervention consisted of three sessions using the routine method, followed by three sessions utilizing the ultrafiltration profile method, which employed an interval with a negative slope. Demographic and clinical information about the patients was recorded on a checklist. Systolic and diastolic blood pressure measurements were taken before the commencement of hemodialysis, at 1-, 2-, and 3-hour intervals post-treatment initiation, and again 15 minutes after completing hemodialysis. Results: The mean blood pressure changes observed during dialysis stages increased with both methods; however, there was a significant difference between the methods (P < 0.001). Specifically, patients receiving the ultrafiltration profile method experienced significantly lower increases in blood pressure compared to those receiving the routine method. Conclusions: Based on the research results, integrating ultrafiltration profiling into hemodialysis can be regarded as an effective and viable strategy for enhancing blood pressure regulation in patients undergoing hemodialysis treatment. Therefore, it is recommended that this approach be considered in hemodialysis programs as well.
The Onset or Worsening of Lower Urinary Tract Symptoms in Patients Infected with COVID-19
Authors: Shokouhi Nasim , Najafizadeh Seyed Reza , Daneshpajoo Parastoo , Nazemi Pershang , Saedi Nafiseh , Feizabad Elham
Published: May 2024

Background: Coronavirus disease 2019 (COVID-19) manifestations are highly diverse, potentially affecting nearly all organ systems during or after infection. Given the importance of a thorough assessment of COVID-19. Objectives: Our study aimed to investigate any new onset or worsening lower urinary tract symptoms (LUTS) in patients infected with COVID-19. Methods: In this cross-sectional study, 88 COVID-19 patients completed the International Consultation on Incontinence Questionnaire-Overactive Bladder and the Overactive Bladder Symptom Score Questionnaires (OABSS). The patients assessed stress urinary incontinence (SUI) and difficulty voiding. Results: Our study revealed that urinary symptoms were the only initial symptom for 28 (31.8%) of the patients or part of the initial symptoms. Furthermore, new onset of OAB symptoms was noted in 35 (39.8%) patients; worsening of pre-diagnosed OAB symptoms was noted in 4 (4.5%) patients; new onset SUI was reported in 17 (32.7%) women, and voiding dysfunction was reported in one woman and two men. There was no significant difference in demographic characteristics, laboratory tests, and lung involvement between patients with and without LUTS (P > 0.05). However, new onset or worsening LUTS significantly (P < 0.001) affected the quality of life. Conclusions: This study demonstrated that LUTS could be the only symptom or one of the initial symptoms of COVID-19. Therefore, physicians should consider COVID-19 as a differential diagnosis in patients presenting with these symptoms.
Is the Serum Prostate-Specific Antigen Level Affected by Urethral Catheterization in Patients with Acute Urinary Retention?
Authors: Shahrokhi Damavand Reza , Akhavan Tavakoli Ardalan , Esmaeili Samaneh , Aali Shahab , Kazemnezhad Ehsan , Kazemi Samira , Abasi Amirhossein
Published: May 2024

Background: The reason for elevated serum prostate-specific antigen (PSA) levels in patients undergoing urethral catheterization due to acute urinary retention (AUR) remains a significant and controversial issue. Objectives: To assess the serum PSA level in men with AUR and its changes after catheterization. Methods: This prospective quasi-experimental study was conducted on 43 patients who underwent transurethral catheterization following AUR caused by benign prostatic hyperplasia (BPH). Total PSA levels and free/total PSA ratios were measured before catheterization and one and three days after catheter insertion. Additionally, prostate volume and urine output after catheterization (UOAC) were recorded. Results: The mean age, prostate volume, and UOAC of the patients were 69.05 ± 9.45 years, 60.51 ± 26.35 g, and 844.04 ± 341.66 mL, respectively. The mean and median baseline total PSA levels were 12.59 ± 17.71 ng/mL and 6.30 ng/mL, respectively. These values changed to 13.73 ± 19.83 ng/mL (median = 4.80 ng/mL) and 11.57 ± 17.70 ng/mL (median = 4.40 ng/mL) after 1 and 3 days of catheterization, respectively. The changes in total PSA and free/total PSA levels during the study period were not statistically significant (P > 0.05). Moreover, the PSA levels showed no statistically significant difference before, 1 day, and 3 days after catheterization in groups with total PSA ≤ 4 and total PSA > 4 (P = 0.37; 0.22, respectively). Conclusions: Our results suggest an initial elevation in PSA levels in patients with AUR before urethral catheterization. Both PSA and free/total PSA ratios showed no statistically significant differences before and after urethral catheter insertion, and initial PSA did not affect its changes after catheterization.
Assessment of musculoskeletal disorders and contributing factors in professional drivers
Authors: Rasheed Moazzam , Riaz Hafiza Mukarma , Arshad Hiba , Fatima Khadija
Published: May 2024

Musculoskeletal disorders (MSDs) are the leading global cause of disability and pose a significant public health issue, particularly among professional drivers who are prone to such conditions due to prolonged sitting, poor posture, and exposure to whole-body vibrations. The objectives of this study are to assess the demographic, general, lifestyle, and wellness profiles of professional drivers, gauge their work environment characteristics, and measure the proportion of musculoskeletal symptoms using the modified Nordic questionnaire. This descriptive study collected data from 67 professional drivers at major bus stands in Lahore using a structured questionnaire. The data were analyzed using frequencies, percentages, means, and standard deviations. The results revealed that the drivers, predominantly middle-aged (average age 39.72 ± 9.53 years) and married (95.52%), reported limited formal education (average 7.56 ± 3.91 years). Lifestyle assessments indicated high rates of smoking (61.19%) and frequent consumption of soft drinks (88.06%). In their work environment, most drivers (68.66%) worked daytime shifts, and a significant proportion (56.72%) experienced vibration exposure. The most frequently reported musculoskeletal symptoms were in the lower back (58.21% in the past 12 months, 43.28% in the past 7 days) and hips/thighs (61.19% in the past 12 months), impacting their ability to work. These findings highlight the critical need for targeted ergonomic and lifestyle interventions to improve the occupational health and safety of drivers, potentially reducing musculoskeletal discomfort and enhancing overall well-being and productivity.
Nonresistant Nonbelief
Authors: Miksa Rad ,   Philosophy Documentation Center
Published: May 2024

The argument from divine hiddenness (ADH) requires accepting that nonresistant nonbelief has existed or does exist. Yet some reasons for accepting nonresistant nonbelief are also reasons for accepting theistic-supporting and naturalism-falsifying evidentially compelling religious experiences (ECREs). Additionally, any reasons for rejecting ECREs can be used to reject nonresistant nonbelief, thus creating parity (at the very least) of epistemic warrant between the two claims. Consequently, accepting nonresistant nonbelief should lead to accepting ECREs. Accepting nonresistant nonbelief therefore indirectly threatens naturalism, atheism and even the ADH itself. To any reason that can be given for rejecting ECREs there corresponds a parallel reason for rejecting nonresistant nonbelief. So it is irrational to accept the ADH while refusing to accept ECREs. Yet the existence of ECREs contradicts the ADH’s conclusion. So the ADH is self-defeating.
Thomas Aquinas on Concrete Particulars
Authors: Skrzypek Jeremy W. ,   Philosophy Documentation Center
Published: May 2024

There are two competing models for how to understand Aquinas’s hylomorphic theory of material substances: the Simple Model, according to which material substances are composed of prime matter and substantial form, and the Expanded Model, according to which material substances are composed of prime matter, substantial form, and all of their accidental forms. In this paper, I first explain the main differences between these two models and show how they situate Aquinas’s theory of material substances in two different places within the contemporary debate on concrete particulars, highlighting several advantages that Aquinas’s approach has over other varieties of substratum and bundle theory along the way. I then offer some reasons to think that the Expanded Model, as a theory of concrete particulars, is preferable. I argue that the Expanded Model avoids two major concerns for the Simple Model: the problem of extrinsicality, and the problem of too-many-possessors.
The Limits of Anti-Anti-Commodification Arguments
Authors: Long Roderick T. ,   Philosophy Documentation Center
Published: May 2024

James Stacey Taylor, in his book Markets With Limits, argues that Jason Brennan and Peter Jaworski, in their book Markets Without Limits, systematically mischaracterize the views of the anti-commodification theorists they are critiquing, attributing to them positions (e.g., semiotic essentialism and an asymmetry thesis) that they do not hold. Further, Taylor offers an anti-commodification hypothesis of his own to explain why talented academics like Brennan and Jaworski could fall into such systematic mistakes – namely, that the intrusion of market norms into academia incentivizes scholars to prioritize original arguments in prominent venues over careful fact-checking. I argue that Taylor is correct in charging that Brennan and Jaworski have gotten their opponents’ views wrong; and I show how their subsequent replies to Taylor’s criticisms have been unconvincing. I also argue, however, that Taylor may be over-hasty in identifying the likely causes of their errors.
Plagiarism, Academic Ethics, and the Utilization of Generative AI in Academic Writing
Authors: Koplin Julian ,   Philosophy Documentation Center
Published: May 2024

In the wake of ChatGPT’s release, academics and journal editors have begun making important decisions about whether and how to integrate generative artificial intelligence (AI) into academic publishing. Some argue that AI outputs in scholarly works constitute plagiarism, and so should be disallowed by academic journals. Others suggest that it is acceptable to integrate AI output into academic papers, provided that its contributions are transparently disclosed. By drawing on Taylor’s work on academic norms, this paper argues against both views. Unlike “traditional” forms of plagiarism, use of generative AI can be consistent with the norms that should underlie academic research. In these cases, its use should neither be prohibited nor required to be disclosed. However, some careless uses of generative AI do threaten to undermine the quality of academic research by mischaracterizing existing literature. This, not “AI plagiarism,” is the real concern raised by ChatGPT and related technologies.
Ethics Ip11 and the Necessary Existence of God
Authors: Cunning David ,   Philosophy Documentation Center
Published: May 2024

A standard reading of the argumentation for Ethics Ip11 has Spinoza contending that because there is no reason or cause for the non-existence of God, God exists, Here I grant that in Ip11 Spinoza is appealing to the claim that there is no reason or cause for the non-existence of God. However, I argue that he is assuming that the existence of God is obvious from Ip7 and Ip8s2 and then positing that because there is nothing that could impede or annul the existence of God, God is a necessary existent. I begin with a discussion of Descartes’s view that the necessary existence of God is independent existence and then I move on to a discussion of the view as it appears in Ip11.
KẾT QUẢ ĐIỀU TRỊ SÙI MÀO GÀ BẰNG PHẪU THUẬT TẠI BỆNH VIỆN DA LIỄU THÀNH PHỐ CẦN THƠ NĂM 2022-2023
Authors: Lê Thị Cẩm Trinh , Nguyễn Trung Kiên , Trần Thái Thanh Tâm , Nguyễn Thị Lệ Quyên
Published: May 2024

Đặt vấn đề: Sùi mào gà là một bệnh chiếm tỷ lệ cao nhất trong những bệnh lây truyền qua đường tình dục, do tác nhân Human Papillomavirus gây ra. Bệnh hay tái phát nhưng chưa có một phương pháp nào điều trị triệt để, đặc biệt đối với các thương tổn lớn, sừng hóa, dễ gây tắc nghẽn. Mục tiêu nghiên cứu: Đánh giá kết quả điều trị sùi mào gà bằng phẫu thuật tại Bệnh viện Da liễu thành phố Cần Thơ năm 2022-2023. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 107 bệnh nhân sùi mào gà từ 18 tuổi trở lên. Các bệnh nhân được điều trị bằng phẫu thuật bằng dao điện cao tần và theo dõi trong 3 tháng. Kết quả: Sau 1 tháng điều trị có 70,1% bệnh nhân đạt kết quả tốt, 29,9% bệnh nhân đạt kết quả chưa tốt. Sau 3 tháng điều trị có 62,6% bệnh nhân đạt kết quả tốt, 37,4% bệnh nhân đạt kết quả chưa tốt. 17,1% bệnh nhân tái phát, thời gian tái phát ngắn nhất là 01 tháng, dài nhất là 02 tháng. Tác dụng phụ bao gồm: 1,87% bệnh nhân chảy máu, 23,4% đau, 14,9% phù nề sau phẫu thuật. Kết luận: Phẫu thuật cắt bỏ có hiệu quả trong điều trị sùi mào gà kích thước lớn, sừng hóa. Tuy nhiên cần phối hợp thêm phương pháp khác để hạn chế tác dụng phụ.
NGHIÊN CỨU TÌNH HÌNH NHIỄM GIUN SÁN Ở SINH VIÊN NĂM THỨ NHẤT TẠI TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2022-2023
Authors: Lê Thị Cẩm Ly , Danh Thanh Nhân , Nguyễn Lê Như Phúc , Nguyễn Trần Thanh Thảo , Đặng Nhật Nam
Published: May 2024

Đặt vấn đề: Khảo sát tỷ lệ nhiễm giun sán và các yếu tố nguy cơ ở sinh viên năm nhất tại Trường Đại học Y Dược Cần Thơ năm 2022-2023 nhằm cung cấp những số liệu thực tế, đóng góp cho công tác phòng chống các bệnh ký sinh trùng và thay đổi hành vi nguy cơ để giảm thiểu tỷ lệ nhiễm. Mục tiêu nghiên cứu: Xác định tỷ lệ nhiễm giun sán ở sinh viên năm thứ nhất Trường Đại học Y Dược Cần Thơ bằng kỹ thuật xét nghiệm phân trực tiếp với dung dịch cố định F2AM và tìm hiểu một số yếu tố ảnh hưởng đến nhiễm giun sán. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 231 sinh viên năm thứ nhất tại Trường Đại học Y Dược Cần Thơ từ tháng 6/2022 đến tháng 6/2023. Kết quả: Trong số 231 sinh viên có mẫu phân đạt chuẩn được xét nghiệm, có 03 sinh viên nhiễm giun móc chiếm tỷ lệ 1,3% và không tìm thấy trường hợp nhiễm giun sán khác Một số yếu tố ảnh hưởng đến nhiễm giun sán như rửa tay trước khi ăn và sau khi đi vệ sinh, đi chân đất. Tuy nhiên, chúng tôi chưa ghi nhận sự khác biệt có ý nghĩa thống kê. Khi nhiễm giun móc thường có các triệu chứng như mệt mỏi, uể oải và tiêu chảy. Kết luận: Tỷ lệ nhiễm giun móc là 1,3%. Một số yếu tố ảnh hưởng đến nhiễm giun như đi chân đất, thói quen rửa tay.