bluuebunny/crossref_metadata_2025 huggingface dataset:
COVID-19 AND DIVIDENDS: EVIDENCE FROM POLAND
Authors: Gemra Kamil , Kwestarz Piotr , Rogowski Waldemar , Lipski Mariusz
Published: June 2022

This paper aims to examine the impact of an unexpected change in the level of dividend caused by the coronavirus (COVID-19) pandemic on share prices on the Polish stock exchange. Our article analyses the period from 1 February 2020 to 5 June 2020, which was when companies listed on the primary market of the Warsaw Stock Exchange (WSE) published information about Boards of Directors’ dividend recommendations for 2019. The original group of companies included 140 firms. 56 companies (40%) fulfilled all the study criteria, and these were subsequently divided into 2 groups. The groups were defined by the recommendations on profit distribution. The first group consisting of 38 companies (68% of the surveyed) consisted of firms which unexpectedly announced plans to retain all profits in the company or a dividend payment but with a lower value than in the previous year (cancellation or reduction of the dividend amount). The second group of 18 companies (32% of the surveyed) comprised those which unexpectedly announced willingness to pay a dividend per share at a higher level (increase in dividend amount). The research confirmed that the announcement of a change in the level of the dividend or the cancellation of the payment of profit is essential price-creating information on the Polish securities market and has a significant impact on the share prices. In a situation of uncertainty caused by external factors, such as the coronavirus pandemic, the sensitivity of individual companies to lockdown and uncertainty as to the return to normality have a significant negative impact on the market. They cause a fall in the share prices higher than expected, especially when they are accompanied by a shortage of information from the companies and a recommendation to suspend or reduce dividend payment.
INSIGHTS INTO PLATFORM TOURISM SERVICES: FUTURE DEMAND PERSPECTIVES IN SLOVAKIA
Authors: Pompurová Kristína , Marčeková Radka
Published: June 2022

A model based on digital sharing has brought a new wind to the business world. Its growth was abruptly disrupted by the COVID-19 pandemic. As anti-epidemiological measures have most significantly affected the tourism sector, this paper attempts to outline the development perspective of platform tourism services. The aim of the paper is to examine the plans of the Slovak population related to the use of platform tourism services after the end of the COVID-19 pandemic. Based on the results of focus groups and questionnaire survey, the paper predicts, that the current crisis will not weaken the development of the tourism platform economy, while demand will be price-driven. As the economy of platform tourism services will be an integral part of our lives for many years to come, it is possible to assume a relentless interest not only of practice, but also of scholars. The research confirms that the accommodation and the transport are the most important paid platform tourism services. They are popular mainly because of the price, not because of the environmental friendliness which denote rather a positive externality of their use. Platform tourism services should be seen as a whole, not as fragments through the prism of selected platforms. The paper highlights information as a key segment and draws attention to the shortcomings of measuring platform services, especially transport ones. Platform tourism services will continue to transform the business. Therefore, it is necessary to better understand it and look for opportunities for its sustainable development. The uniqueness of the current study lies, among others, in the use of mixed methods which help to comprehensively understand the problem in depth and breadth.
INNOVATIVE ACTIVITY OF RESTAURANTS OPERATING IN THE LARGEST POLISH CITIES
Authors: Rapacz Andrzej , Gryszel Piotr , Walesiak Marek , Dudek Andrzej
Published: June 2022

The skills of acquiring and processing information as well as creating innovations remain the key factor responsible for the market success of enterprises, one of the most important factors in gaining a competitive advantage on the market. It is also true for the tourism market of which catering services make an essential part. Hotel industry has been the subject of intensive research in this area for over 2 decades. Much less scientific attention has been paid to innovation in the restaurant sector. Therefore, the intention of the authors of this study was to analyse the process of creating innovations in restaurants operating in the largest Polish cities. The study identifies the factors responsible for the innovative activity of restaurants, perceived from the perspective of their managers. For this purpose, a multivariate method, in the form of classification trees, was used. The research material was collected in the course of a survey carried out in 250 restaurants. As a result of the applied research methods, the innovation factors were specified and 4 segments of innovative restaurants in Poland were identified. These segments are made up of 75% of restaurants applying pro-innovative activities, which for them represent an important aspect of market success. Pro-innovative activities are implemented more often by chain restaurants as well as the ones operating in hotel facilities. Small, family-run restaurants use innovations on a smaller scale. They refer to selected restaurants operating in the 6 largest Polish cities, which limits the possibility of making generalizations regarding other forms of catering establishments functioning in other geographical locations. Future research should cover a wider group of catering establishments, in various locations.
Novel GLCCI1-BRAF fusion drives kinase signaling in a case of pheochromocytomatosis
Authors: Green Benjamin L , Grant Robert R C , Richie Christopher T , Chatterjee Bishwanath , Sampaio De Melo Michelly , Barr Frederic G , Pacak Karel , Agarwal Sunita K , Nilubol Naris
Published: June 2022

Introduction

Recurrent and metastatic pheochromocytoma (PCC) are rare advanced endocrine neoplasms with limited treatment options. Insight into the pathogenic molecular alterations in patients with advanced PCC can provide therapeutic options for precisely targeting dysregulated pathways.

Objective

We report the discovery and characterization of a novel BRAF-containing fusion transcript and its downstream molecular alterations in a patient with recurrent PCC with peritoneal seeding (pheochromocytomatosis).

Methods

We reviewed the medical record of a patient with pheochromocytomatosis. A comprehensive pan-cancer molecular profiling using next-generation sequencing (NGS) as well as confirmatory real-time-quantitative PCR were performed on surgical specimens. BRAF rearrangement and downstream molecular changes were assayed using fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC), respectively. Western blot was used to assess the in vitro activation of the mitogen-activated protein kinase (MAPK) signaling pathway and the EMT markers in transfected HEK-293 cells.

Results

The NGS analysis of a specimen from a 72-year-old female patient with pheochromocytomatosis showed an in-frame fusion of exon 3 of Glucocorticoid Induced 1 (GLCCI1) to exon 9 of BRAF. The upstream auto-inhibitory domain of BRAF was excluded from the GLCCI1-BRAF fusion; however, the downstream BRAF kinase domain was intact. A BRAF rearrangement was confirmed via a BRAF-specific break-apart FISH assay. Four separate tumor foci harbored GLCCI1-BRAF fusion. IHC demonstrated increased phosphorylated MEK. HEK-293 cells transfected with the GLCCI1-BRAF fusion demonstrated increased phosphorylated MEK as well as higher expression of EMT markers SNAI1 and ZEB1 in vitro.

Conclusion

We demonstrate a novel pathogenic gene fusion of GLCCI1 with the oncogenic kinase domain of BRAF, resulting in an activation of the MAPK signaling pathway and EMT markers. Thus, this patient may benefit from clinically available MEK and/or BRAF inhibitors when systemic therapy is indicated.

Summary statement

This report is the first of GLCCI1 fused to BRAF in a human neoplasm and only the second BRAF-containing fusion transcript in PCC. Detailed molecular characterization of PCC can be a valuable tool in managing patients with recurrent PCC and pheochromocytomatosis that represents a significant clinical challenge.
Ao muito unrado senor e sages don Ruy Garcia de Pavia. Novos testemunhos da afloração e expansão do (galego-)português como língua escrita em Portugal
Authors: Souto Cabo José António
Published: June 2022

Este trabalho inclui a edição e estudo de cinco documentos em galego-português inéditos custodiados no Arquivo Nacional da Torre do Tombo e produzidos em Portugal entre finais do séc. xii (ca. 1188-1192) e 1270. O mais antigo é uma “notícia” probatória relativa ao processo de inquirição pelo qual uma propriedade em Friamil (Castelo de Paiva) foi reconduzida ao domínio régio. Pela datação (crítica), ele passa a integrar o diminuto grupo de exemplares em português inseríveis nas últimas décadas do séc. xii. O segundo escrito (1243), além de constituir um dos primeiros espécimes de natureza dispositiva em romance, encerra uma novidade gráfica de grande relevo: os primeiros usos do traço supralinear como diacrítico de nasalidade vocálica. A terceira parte deste artigo inclui três documentos da segunda metade do séc. xiii, cada um com características singulares. O mais antigo, um relatório económico duplo elaborado para Rui Garcia de Paiva por dois seus vassalos (ca. 1265), aproxima-se do género epistolar, o que se traduz no plano linguístico por traços expressivos inéditos fora da criação literária. Quanto ao contrato estabelecido entre esse mesmo Rui Garcia e a Ordem de Santiago em 1268, a par doutros aspetos significativos, serve como exemplo do influxo exercido por um modelo de escrita alóctone, neste caso castelhana, em território português. O último texto, lavrado em 1270 por Gil Vicente, constitui uma relevante amostra do apurado domínio dos recursos gráficos, quase em termos de modelo normativo na época.
Comparative Study on Interphase Force Model of Gas-Liquid Two-Phase Bubbly Flow Based on OpenFOAM
Authors: Liu Chang , Wu Haochuang , Lu Wei , Chen Deqi , Pan Junjie , Li Zhenzhong , Feng Jintao
Published: June 2022

It is essential to choose an appropriate interphase force model when studying gas-liquid two-phase bubbly flow by numerical calculation. Because of the complexity of gas-liquid interaction, researchers have developed many models, while there is still a lack of corresponding guidelines when selecting the combination of interphase force models. In the present study, taking the DEDALE experimental condition as the research object, the parameter distribution characteristics of void fraction and gas-liquid two-phase velocity under the experimental condition are simulated, and the calculation results of different interphase force models are analyzed and compared with the experimental results. The effects of different interphase force models on the local parameter distribution characteristics of the two phases are analyzed and discussed, and the optimal model combination under this experimental condition is obtained.
Foreign Exchange Volatility and the Bubble Formation in Financial Markets: Evidence From The COVID-19 Pandemic
Authors: Özdemir Onur
Published: June 2022

This paper applies recursive right-tailed unit root tests to detect bubble activity for Turkish Lira against financially most-traded five currencies (i.e., the US Dollar (USD/TRY), the British pound (GBP/TRY), the Euro (EUR/TRY), the Chinese Yuan (CNY/TRY) and the Russian Ruble (RUB/TRY)) over January 2, 2015 to February 12, 2021. It can be identified from the Supremum Augmented Dickey–Fuller (SADF) and the Generalized Supremum Augmented Dickey-Fuller (GSADF) tests statistics that there is a high degree of evidence of bubble activity which characterizes all five exchange rates both in the full-sample period and in the sub-periods, including the pre-COVID-19 era (January 2, 2015 to November 15, 2019) and the COVID-19 era (November 18, 2019 to February 12, 2021). The empirical results also indicate that positive bubbles are common for each selected exchange rate and the multiple bubbles were intensified during the COVID-19 period, referring that forex markets became relatively more inefficient compared to the pre-COVID-19 period.
A DILATOMETER FOR THE CARBON FIBER COMPOSITE TUBES
Authors: Dergal E.S. , Kudrevatykh O.T. , Quinn N.O.
Published: June 2022

A device and method for measuring the coefficient of thermal expansion of composites based on digital recordings of the indicating laser spot displacement has been developed.  Specific holders for support of the test object and an optical arrangement of the dilatometer are proposed to measure the deformation of the carbon fiber reinforced compositetubes due to temperature changes. The advantages of the system include high sensitivity and the ability to examine composite tubes with varied length (from 0,2 m to 2 m) with high accuracy. A special heating system for temperature changes in examined objectsbased on conductivity of carbon fiber has been developed. The sensitivity of the dilatometer can be adjusted in according to the size of examined objects.
НАЗЕМНОЕ ОБЕСПЕЧЕНИЕ ПОЛЕТНОЙ И ЭКСПЛУАТАЦИОННОЙ РАДИОМЕТРИЧЕСКОЙ КАЛИБРОВКИ ОПТИЧЕСКОЙ ПОЛЕЗНОЙ НАГРУЗКИ КОСМИЧЕСКОГО АППАРАТА
Authors: Луць О. В. , Борщева Г. А. Борщева , Ярмольчук Е. Д. , Манойленко А. А.
Published: June 2022

A description of the proposed ground support for flight and operational radiometric calibration of the optical payload is given. Initial positions and  assumptions  adopted   during

the development of calibration algorithms are formulated. The definitions of basic quantities and used quantitative ratios are given. An algorithm for calculating the energy brightness of the radiation when shooting test objects is proposed. An example of calculating the calibration characteristics of the spectral channels of the payload is given, and an estimate of the calculation error is made.
ПРИМЕНЕНИЕ СОВРЕМЕННЫХ ПРОГРАМНЫХ КОМПЛЕКСОВ ПРИ ПРОЕКТИРОВАНИИ И ИЗГОТОВЛЕНИИ ФЛАНЦА ТОПЛИВНОГО БАКА ИЗ УГЛЕПЛАСТИКА
Authors: Манько Т.А. , Литот А.В.
Published: June 2022

The article is devoted to the use of modern software systems in the design and manufacture of products from polymer composite materials on the example of creating a flange of the fuel tank for cryogenic components of carbon fiber. Some results of carbon fiber flange throughput and field tests are given. Conclusions of the work performed and evaluation of results.
ХОЛЛОВСКИЙ ДВИГАТЕЛЬ ST-25 ДЛЯ МАЛЫХ КОСМИЧЕСКИХ АППАРАТОВ
Authors: Петренко А.Н. , Кулагин С.Н. , Толок С. , Сербин В.В. , Вороновский Д. , Маслов В.
Published: June 2022

Results of development and experimental tests of Hall Thruster ST-25 are presented. This thruster is intended for application on small space vehicles. With the purpose of decrease of input electric power in the magnetic system   of thruster a permanent   magnet   is applied. In the process of the thruster development his laboratory tests were conducted with the laboratory prototypes of electric power supplies. Final tests were conducted with the flying prototype of discharge power supply. Laboratory tests have confirmed the rightness of the technical decisions stopped up in the construction of Thruster. Methodology of the thruster ST-25 start at the use of preheated cathode and flying prototype of the discharge power supply were improved. Possibility of application of such type of Hall Thrusters on space vehicles with the size of on-board electric power of that is limited to the size 300 - 500 W were confirmed.
МОДЕЛЮВАННЯ РУХУ ТА ВИЗНАЧЕННЯ КІНЕМАТИЧНИХ ХАРАКТЕРИСТИК КУЛАЧКОВОГО МЕХАНІЗМУ З ВИСТОЯМИ У ПРОГРАМНОМУ СЕРЕДОВИЩІ «APM INTEGRATOR»
Authors: Сокол Г. І. , Сахно О. А. , Білоус В. В.
Published: June 2022

The simulation of motion and determination of kinematic characteristics of the cam mechanism using the software package «APM INTEGRATOR» are considered. This allowed simulating the motion of the link mechanism in the animation.
ЩОДО КОНЦЕПЦІЇ СТВОРЕННЯ ВУЗЛІВ СТИКУВАННЯ СИСТЕМ ТЕРМОСТАТУВАННЯРАКЕТ КОСМІЧНОГО ПРИЗНАЧЕННЯ
Authors: Хорольський М.С. , Бігун С.О.
Published: June 2022

The article presents the key results of analysis of the available technical solutions for creating thermal conditioning system interfaces for integrated launch vehicles and describes their drawbacks. The article proposes a new design concept for the interfaces that includes an integrated rubber hose composed of three basic parts attached to the inlet tube of the carrier rocket with the help of a lock/ lock release assembly ensuring air tightness of the thermal conditioning system and disconnection with minimal effort during the launch of the vehicle.
ОЦІНКА МОЖЛИВОГО УРАЖЕННЯВІД ВИБУХУПАЛИВНО-ПОВІТРЯНИХ СУМІШЕЙ ПРИ ПРОЕКТУВАННІ СПЕЦІАЛЬНИХ ОБ'ЄКТІВ ІНФРАСТРУКТУРИ
Authors: Шевцов В.Ю. , Левченко В.Ю.
Published: June 2022

The methodology for calculating the damaging factors proposed in the article depending on the energy of the explosion and the distance allows one to predict both the reliable distance of the location of civilian structures and their strength, which provides reliable protection for the personnel of a particular object. In addition, this technique allows you to identify possible ways to increase the explosion safety of fuel assemblies with the main criterion - “personnel protection / minimization of damage».
percepção de docentes a respeito de Atividades não Presenciais realizadas durante o isolamento social causado pela pandemia da COVID-19
Authors: Accordi Iury de Almeida , Ambr´´osio-Accordi Andréia
Published: June 2022

Objetivou-se analisar a percepção de docentes sobre as atividades não presenciais (ANP), realizadas durante o distanciamento social causado pela pandemia da COVID-19, no Instituto Federal de Santa Catarina (IFSC), que optou por ANP e o Instituto Federal do Rio Grande do Sul (IFRS), que suspendeu suas atividades formais durante o período inicial da pandemia. Aplicou-se um formulário on-line e foram analisadas as respostas de 283 docentes. Apesar das decisões institucionais distintas, não se notou respostas muito diferentes dos docentes de ambas as instituições em relação à maioria das questões. A maioria dos docentes manifestou ser favorável às ANPs e buscou se capacitar para melhor enfrentar a nova situação. Os docentes buscaram formas sólidas de se capacitarem didática e pedagogicamente para a aplicação de um ensino não presencial, bem como de se comunicarem de forma efetiva com seus discentes. Conclui-se que o aprendizado com as ANPs fornecerá uma base sólida para um novo tipo de interação docente/discente, potencializando o uso de tecnologias emergentes na aplicação de atividades e estendendo a comunicação por meio das mídias a aplicativos sociais disponíveis.
Palavras-chave: Tecnologias emergentes; ensino remoto; Institutos Federais.
Work-related informal learning in knowledge-intensive industry
Authors: Gáthy-Stéber Andrea
Published: June 2022

This study investigates occurrences and tools of informal and non-formal learning at work, focusing on the Hungarian IT sector. The aim is to demonstrate that learning at work mainly manifests informally and to identify its patterns. Companies shifting towards teleworking during the pandemic further increased the importance of informal learning. The empirical research uses complex methodology of three pillars: A questionnaire about workplace learning conducted among employees in the IT sector (N = 162). Case studies of three Hungarian IT companies using questionnaires and semi-structured interviews. Learning activity logging of work-related learning events were recorded by participating employees (N = 19). According to the main conclusions there is a positive correlation between the number of available workplace learning opportunities and opinions on the efficacy of informal learning. Informal learning dominates the learning patterns of employees in a knowledge-intensive industry. In supporting employees’ learning the average number of informal learning opportunities are significantly higher than those of formal learning and both employees and employers agree that this mode of learning is more effective.

The results highlight that reinterpreting workplace learning is necessary due to economic, social and technological trends not to mention employer flexibility becoming more and more inevitable. Thus, the importance of informal learning is unquestionable.
Advancement of inductive reasoning of engineering students
Authors: Tóth Peter , Pogatsnik Monika
Published: June 2022

The task of higher education is twofold: (1) to prepare students to meet the expectations of the labor market and (2) to create a learning environment and conditions so that as many students can meet the subject requirements as possible, the dropout rate should be the lowest possible. Input and continuous monitoring of students' transversal competencies can be a suitable method to meet this dual requirement. The range of these competencies is very diverse. In our present study, we focused on inductive thinking, which plays an important role in problem-solving. The research involved 212 first-grade BSc technical students. Our measurement tool is widely used in the selection of the workforce, which the students had to fill in online. The gained results were evaluated using IBM SPSS Statistics. The analysis included a comparison of inductive thinking and its two subcomponents, abstract reasoning, and diagrammatic cognition, in terms of background variables, as well as time consumption, and the definition of specific performance. We found a functional relationship between time consumption and the performance achieved in the test. Students have advanced analogical cognition in terms of abstract thinking; however, their diagrammatic thinking shows very different levels of development, which can cause difficulties in solving technical problems.
Mutational and bioinformatics analysis of the NKX2.1 gene in a cohort of Iranian pediatric patients with congenital hypothyroidism (CH)
Authors: Heidari Mohammad Mehdi , Madani Manshadi Seyed Ali , Eshghi Ahmad Reza , Talebi Fatemeh , Khatami Mehri , Bragança José , Ordooei Mahtab , Chamani Reyhane , Ghasemi Farzaneh
Published: June 2022

Congenital hypothyroidism (CH) occurs with a relatively alarming prevalence in infants, and if not diagnosed and treated in time, it can have devastating consequences for the development of the nervous system. CH is associated with genetic changes in several genes that encode transcription factors responsible for thyroid development, including mutations in the NK2 homeobox 1 (NKX2.1) gene, which encodes the thyroid transcription factor-1 (TTF-1). Although CH is frequently observed in pediatric populations, there is still a limited understanding of the genetic factors and molecular mechanisms contributing to this disease. The sequence of the NKX2.1 gene was investigated in 75 pediatric patients with CH by polymerase chain reaction (PCR), single-stranded conformation polymorphism (SSCP), and direct DNA sequencing. Four missense heterozygous variations were identified in exon 3 of the NKX2.1 gene, including three novel missense variations, namely c.708A>G, p.Gln202Arg; c.713T>G, p.Tyr204Asp; c.833T>G, p.Tyr244Asp, and a previously reported variant rs781133468 (c.772C>G, p.His223Gln). Importantly, these variations occur in highly conserved residues of the TTF-1 DNA-binding domain and were predicted by bioinformatics analysis to alter the protein structure, with a probable alteration in the protein function. These results indicate that nucleotide changes in the NKX2.1 gene may contribute to CH pathogenesis.
Current Understanding of Maternal Healthcare Acceptability from Patients’ Perspectives
Authors: Bucyibaruta Joy Blaise , Maidment Leah , Heese Carl August Daniel , Peu Mmapheko Doriccah , Bamford Lesley , Van der Wath Annatjie Elizabeth , Grobler Estelle , Musekiwa Alfred
Published: June 2022

The importance of healthcare acceptability concept cannot be overlooked in health sciences including psychology, yet, it remains controversial and it is poorly understood by all health researchers. This concept cuts across all health disciplines and it refers to human behaviour such as attitude, trust, and respect through interactions between patients and health professionals. Many studies have been published on acceptability of maternal healthcare, but there is no consensus on how it is defined and conceptualised. Thus, this study aims at reviewing existing literature to shed light on the definition and conceptualisation of maternal healthcare acceptability from the patients’ perspectives. This study will apply scoping review to reach its broad purpose. The search of relevant articles from electronic and grey literature will be guided by a search strategy developed based on eligibility criteria. Two researchers will independently screen the retrieved articles using Rayyan software and chart data from included articles. An agreement of 80% between them will be considered appropriate. This study will provide a general interpretation of key findings in line with available evidence and consistent with the research purpose. The researchers will discuss the study’s limitations and propose potential implications and future research projects.
Antiproliferative properties and evaluation of antioxidant of different cornelian cherry genotypes and analysis of phenolic and sugar compounds by HPLC
Authors: UĞUR Yılmaz , ŞALVA Emine , KARAAT Fırat , ERDOĞAN Selim
Published: June 2022

Bu çalışmanın amacı, kızılcık meyvelerinin kimyasal bileşimi (C vitamini, bireysel fenolik ve şeker bileşikleri) ve antioksidan kapasitesinin yanında, meyve ekstrelerinin sağlıklı (L-929) ve akciğer kanseri (A-549) hücreleri üzerindeki sitotoksik etkisini araştırmaktır. Türkiye'de aynı koşullarda yetiştirilen on üç kızılcık (Cornus mas L.) genotipi meyve örnekleri ASE tekniği ile optimum koşullarda ekstrakte edildikten sonra kimyasal bileşim, HPLC-DAD-RID ile analiz edildi. Antioksidan kapasitesi, toplam fenolik ve toplam antosiyanin içeriği spektrofotometrik yöntemler kullanılarak belirlendi. Sitotoksik etkiler, 48 saat boyunca L-929 ve A-549 hücre hatlarında MTT testi ile değerlendirildi. Meyve ekstraktlarının L-929 sağlıklı fare fibroblast hücreleri üzerinde toksik etkisi gözlenmezken, A-549 akciğer kanseri hücrelerinde hücre proliferasyonunu (yaklaşık %50) azalttığı belirlendi. A-549 hücreleri üzerindeki antioksidan kapasite ve sitotoksik etkiler için öne çıkan genotipler sırasıyla 44-03, 44-20, 44-21, 77-09 ve 44-21, 44-16, 77-05 olduğu belirlendi. Elde edilen sonuçlar, genotipler (p ≤ 0.05) arasında önemli farklılıklar olduğunu ve kızılcık meyvelerinin önemli bir antioksidan kapasiteye ve antiproliferatif etki potansiyeline sahip olduğunu ortaya koymuştur.
Age, motor dysfunction and neuropsychiatric symptoms impact quality of life in multiple sclerosis
Authors: Brandão Patrícia de Morais Ferreira , Lino Tayla Borges , Oliveira Renata Terra de , Parra Andrelisa Vendrami , Andrade Paulo Henrique Muleta , Christofoletti Gustavo
Published: June 2022

ABSTRACT Objectives: to investigate the impact of age, motor dysfunction and neuropsychiatric symptoms on the quality of life of people with multiple sclerosis in comparison to healthy peers. Methods: a total of 141 participants were tested in a single session. The assessments were composed by general questionnaires applied in both groups and by specific instruments restricted to multiple sclerosis. Multiple regression models were applied to assess relationships between predictors and outcome. Results: age, motor dysfunction and neuropsychiatric symptoms explained 56.6% of quality of life of the multiple sclerosis group. Age and neuropsychiatric symptoms explained 36.6% of quality of life in the control group. Age impacted more the multiple sclerosis group than the control group. Neuropsychiatric symptoms affected both groups similarly. Motor dysfunction impacted 21.9% of the quality of life in multiple sclerosis. Conclusions: the predictors explained considerable variance of quality of life in multiple sclerosis, which should guide public health policies.
Preventing COVID-19 as a nursing student through social networks in their family-social environment
Authors: Falcón Gladys Carmela Santos , Moncada María Josefa Arcaya , Rojas Teresa Catalina Surca , Arias Gladys Filomena García , Camacho Cecilia Victoria Chávez , Correa Maria Isabel del Milagro Mendoza , Lluncor Esperanza Margarita Lluncor
Published: June 2022

ABSTRACT Objective: to analyze and understand COVID-19 prevention by nursing students through social networks in their family-social environment. Method: a qualitative descriptive-interpretative study, developed in the nursing school of a public university in Lima, Peru, from October to December 2020. Students from the fourth and fifth year of studies participated. Data were collected with the technique of focus groups (2) and analyzed with thematic content analysis. Results: two categories emerged: Using various social networks in times of pandemic; Considering themselves trained for COVID-19 prevention through social networks in their family-social circle. Final considerations: nursing students carry out COVID-19 prevention in their family-social circle through social networks, showing satisfaction in the transmission of knowledge, considering the people’s physical-emotional condition and local health status, perceiving themselves as agents of change, seeking people empowerment.
Effect of the Surgical Safety Checklist on the incidence of adverse events: contributions from a national study
Authors: FARIA LUCIANE RIBEIRO DE , MOREIRA TIAGO RICARDO , CARBOGIM FÁBIO DA COSTA , BASTOS RONALDO ROCHA
Published: June 2022

ABSTRACT Objective: the study evaluated the effect of using the safe surgery checklist (CL) on the incidence of adverse events (AE). Methods: cross-sectional and retrospective research with 851 patients undergoing surgical procedures in 2012 (n=428) and 2015 (n=423), representing the periods before and after CL implantation. The AE incidences for each year were estimated and compared. The association between the occurrence of AE and the presence of CL in the medical record was analyzed. Results: a reduction in the point estimate of AE was observed from 13.6% (before using the CL) to 11.8% (with the use of the CL). The difference between the proportions of AE in the periods before and after the use of CL was not significant (p=0.213). The occurrence of AE showed association with the following characteristics: anesthetic risk of the patient, length of stay, surgery time and classification of the procedure according to the potential for contamination. Considering the proportion of deaths, there was a significant reduction in deaths (p=0.007) in patients whose CL was used when compared to those without the use of the instrument. There was no significant association between the presence of CL and the occurrence of AE. It was concluded that the presence of CL in the medical record did not guarantee an expected reduction in the incidence of AE. Conclusion: however, it is believed that the use of the instrument integrated with other patient safety strategies can improve the safety/quality of surgical care in the long term.
DUAS INTERPRETAÇÕES DO EMPRESÁRIO INDUSTRIAL E DESENVOLVIMENTO ECONÔMICO, DE FERNANDO HENRIQUE CARDOSO
Authors: Costanzo Daniela , Marino Rafael
Published: June 2022

Resumo O objetivo deste trabalho é apresentar as interpretações do livro Empresário Industrial e Desenvolvimento Econômico, de Fernando Henrique Cardoso, encontradas na literatura sobre empresários no Brasil. Mais especificamente, pretende-se mostrar como os autores que vieram depois de Cardoso leram a atuação política dos empresários industriais em sua obra. O artigo busca oferecer também uma interpretação alternativa da obra do sociólogo uspiano, desenvolvendo o argumento em duas chaves. Por um lado, são questionadas tais leituras sobre o empresariado industrial no Brasil, utilizando a própria obra do autor. Por outro, busca-se esclarecer seu método e a sua incompatibilidade com a leitura proposta por seus críticos. Isso tudo com o fito de mostrar que Cardoso apreendeu as determinações específicas da burguesia nacional e seu comportamento político, sem decalques estrangeiros.
Identification of SCAR markers for genetic authentication of Dendrobium nobile Lindl.
Authors: Deng H. , Khan M.A. , Liu X. , Fu J. , Mei Z.
Published: June 2022

Abstract Dendrobium nobile Lindl. is an orcid plant with important medicinal values. This is a colourful houseplant, and also a popular herb in traditional Chinese medicine (TCM). The variants of this plant from different geographic regions might be high, and in this study, we aimed to develop specific sequence characterized amplified region (SCAR) markers for the identification of specific variant of this plant. Different cultivars of D. nobile were collected from nine different places of China, and one cultivar from Myanmar. DNA materials were extracted from the plant samples, random amplified polymorphic DNA (RAPD) were developed, cloned and sequenced for the development of SCAR markers. We have developed four SCAR markers, which are specific to the cultivar from Luzhou China, and clearly distinguishable (genetically) from other cultivars. These SCAR markers are deposited in GenBank (accession number MZ417502, MZ484089, MZ417504 and MZ417505). Four SCAR markers for D. nobile are effective molecular technique to genetically identify the different cultivars or species, and this method is applicable for genetic characterization and identification of other plant species too.
Drought variability assessment using standardized precipitation index, reconnaissance drought index and precipitation deciles across Balochistan, Pakistan
Authors: Qaisrani Z. N. , Nuthammachot N. , Techato K. , Asadullah  , Jatoi G. H. , Mahmood B. , Ahmed R.
Published: June 2022

Abstract Drought variability analysis is of utmost concern for planning and efficiently managing water resources and food security in any specific area. In the current study, drought spell occurrence has been investigated in the Balochistan province of Pakistan during the past four decades (1981-2020) using standardized precipitation index (SPI), reconnaissance drought index (RDI), and precipitation deciles (PD) at an annual timescale. Precipitation and temperature data collected from 13 synoptic meteorological stations located in Balochistan were used to calculate the SPI, the RDI, and the PD for calculation of drought severity and duration. Based on these indices, temporal analysis shows adverse impacts of drought spells in Nokkundi during 1991-1993, in Barkhan, Dalbandin, Quetta stations during 1999-2000, whereas Barkhan, Dalbandin, Lasbella, Sibi during 2002-2003, Zhob during 2010-2011, Kalat and Khuzdar during 2014-2015, and Panjgur during 2017-2018. Also, the aridity index for each station was calculated based on the UNEP method shows that major part of Balochistan lies in the arid zone, followed by the hyper-arid in the southwestern part and the semi-arid zones in the northeastern part of the province. SPI and RDI results were found more localized than PD, as PD shows extensive events. Furthermore, principal component analysis shows a significant contribution from all the indices. For SPI, RDI, and PD, the first three principal components have more than 70% share, contributing 73.63%, 74.15%, and 72.30% respectively. By integrating drought patterns, long-term planning, and preparedness to mitigate drought impacts are only possible. The RDI was found more suitable and recommended in case of temperature data availability.
Plano de texto de “mensagens de natal” na cena política luso-brasileira
Authors: Pita Sara Topete de Oliveira
Published: June 2022

Na cena política, as Mensagens de Natal assumiram um estatuto de tradição, mas será o seu plano textual fixo ou ocasional, como postula Adam (2002)? No sentido de identificar a estrutura organizativa destes textos, procedeu-se a uma análise diacrónica de textos de Portugal e do Brasil (produzidos de 2008 a 2020), com foco nos processos de distribuição e segmentação do texto (Silva, 2016). Assim, a análise focou-se na composição gráfica, na distribuição temática e, sobretudo, nos mecanismos articulatórios que asseguram a coesão textual (organizadores, marcadores/conectores, cadeias de referência). Os resultados apontam para uma estrutura em quatro blocos - exórdio, performance governativa, compromissos de futuro, peroração, alterada conforme as necessidades comunicativas. Os blocos inicial e final têm um pendor emotivo, relacionado com a época natalícia e seus valores, e os blocos centrais são de cariz objetivo, apresentando provas do desempenho e intenções governativas. Em virtude da flexibilidade que demonstram, considera-se que o plano de texto destas intervenções políticas é ocasional, não obstante existirem alguns segmentos frequentes.
Acinetobacter calcoaceticus-Acinetobacter baumannii complex in animals: identification and antimicrobial resistance profile
Authors: Holmström Thérèsse C.H. , David Luria A. , Motta Cássia C. , Rocha-de-Souza Claudio M. , Maboni Grazieli , Coelho Irene S. , Melo Dayanne A. , Souza Miliane M.S.
Published: June 2022

ABSTRACT: Acinetobacter spp. is emerging as an important human and veterinary pathogen, mostly due to intrinsic and acquired resistance to antimicrobials. Despite its public health relevance, little is known about the prevalence, role of different Acinetobacter species and antimicrobial resistance profile of animal-origin isolates. Traditional phenotypic tests may fail to discriminate Acinetobacter species, therefore molecular analyses are often required as a complementary approach. The objectives of this study were to evaluate the occurrence of strains of the Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex isolated from animal infections including urinary tract infections, otitis, piodermitis and pododermatitis, and its resistance profile against different antimicrobial classes, including carbapenems. All Gram-negative coccobacilli isolates were characterized by MALDI-TOF and multiplex PCR, and the disk diffusion test was used to investigate multi-drug resistance (MDR) and carbapenem resistance genes by PCR as preconized by the standard guidelines. MALDI-TOF technique identified 21 strains belonging to the Acb complex (10 A. pittii, 8 A. baumannii, 3 A. nosocomialis, 1 A. ursingii, and 1 A. venetianus). Multiplex PCR confirmed the results of MALDI-TOF for 20 strains. Eight strains (34.78%) were classified as MDR, being 50% (4/8) A. baumannii, 37.5% (3/8) A. pittii, and 12.5% (1/8) A. nosocomialis. None of the isolates presented phenotypic carbapenemase production. Considering the carbapenem resistance genes, 26.09% (6/23) of the isolates presented one or more carbapenemase genes. From these, 50% (3/6) presented only bla VIM, 33.33% (2/6) presented only blaIMP, and 16.67% (1/6) presented blaIMP e blaVIM, simultaneously. These genes were detected among A. pittii isolates mostly (66.67%, 4/6). This study provides further insights into the occurrence and resistance profile of Acinetobacter of animal origin.
BIOMASS OF TWO Eucalyptus CLONES (E. grandis × E. urophylla) IRRIGATED WITH SALINE WATER
Authors: Castro Filho Manoel Nelson de , Tagliaferre Cristiano , Oliveira Fabiano de Sousa , Silva Bismarc Lopes da , Alves Rafael Oliveira , Paula Alessandro de , Barros Flavia Mariani
Published: June 2022

ABSTRACT Using saline water for irrigation relies on strategies that include selecting salt-tolerant cultivars and leaching salts away from zones close to the roots. A greenhouse experiment was carried out to assess early growth and biomass production of two Eucalyptus clones (E. grandis × E. urophylla), CO 865 and CO 1407, irrigated with saline water and under different leaching fractions. Treatments were laid out in a randomized block design and arranged in a 4 × 2 + 2 factorial scheme: four leaching fractions (3, 10, 20, and 30 % of crop water demand for plants irrigated with saline water), two Eucalyptus clones (VCC 865 and CO 1407), and two additional treatments, one for each clone, conventionally irrigated with fresh water. The treatments were replicated four times. Measurements were made at 114 days after transplanting. Soil salinity decreased with increasing leaching fraction where VCC 865 was grown; however, leaf dry weight production was lower in treatments irrigated with saline water. Compared to fresh water-irrigated plants, irrigation with saline water resulted in lower: canopy diameter, leaf number, dry leaf mass, dry root mass, aerial parts dry mass, aerial part/root ratio, and total plant dry weight. Overall, the VCC 865 Eucalyptus clone performed better under saline irrigation than CO 1407.
TREE SPECIES OF ATLANTIC FOREST AND PAMPA ALLUVIAL FORESTS IN THE CONTEXT OF CLIMATE CHANGE
Authors: Silva Jessica Oneda da , Galvão Franklin , Silva Ana Carolina da , Higuchi Pedro
Published: June 2022

ABSTRACT Although species are continually exposed to variations in climate over time, there is growing concern about the accelerated pace of climate change to which they are currently exposed, as climate is determinant in the geographic distribution of animals and plants. This study evaluated the climatic niche and impact of climate change in the 2061-2080 period on areas of occurrence of indicator tree species of alluvial forests in the south-central portion of the Atlantic Forest and Brazilian Pampa. Nineteen climatic variables were considered for the contemporary and future climates. The species’ climatic niches were modeled using the Maxent algorithm. Climatic adequacy for species in the Parana-Uruguay group was strongly influenced by variables related to temperature, while adequacy for species in the Atlantic group was related to rainfall and temperature. A decrease in the area of climatic adequacy is estimated for most species considered, with similar behavior in the two groups assessed. The species tend to occupy a more southern position, using areas of higher altitude, latitude and proximity to the Brazilian coast as climate refuges, highlighting these areas as strategic for environmental conservation.
Pinewood protection against sapstain using citrus essential oils
Authors: Martínez-Pacheco Mauro Manuel , Reynoso Wuilver Elder García , León José Cruz de , González David Raya , García Alberto Flores , Rojas Abril Munro , Becerra Crisanto Velázquez
Published: June 2022

ABSTRACT Natural color influences the decision to acquire a wood product. Sapstain is a fungal deterioration of pinewood that affects its aesthetic attributes and generally causes its rejection. The aim was to control the sapstain on pinewood with citrus essential oils. Causal agents of sapstain on pinewood were identified by molecular methods to genus level as Alternaria sp., Hypocrea sp., Trichoderma sp., and Geosmithia sp. Citrus essential oils were tested to control the fungal growth. For the treated pinewood probes, the adsorption and retention of citrus essential oils, fungal adhesion, and wood satin as fungal growth indicators were determined. The composition of the essential oils was determined by gas chromatography. Fungi were sensible to essential oils rich in D-limonene, γ-terpinene, α-terpineol, geraniol, eugenol, or β-bisabolene. Absorption and retention data suggest that 12.37±1.62 kg/m3 is the minimal amount to inhibit the fungal adhesion and growth on pinewood. Citrus essential oils control sapstain in pinewood, but poor retention should be improved.
Initial growth of forage cactus clones at different potassium fertilization levels
Authors: Cirino Junior Baltazar , Leite Maurício Luiz de Mello Vieira , Silva Fábio Eráclito da , Alves Cleber Pereira , Oliveira Alexandre Campelo de , Eugênio Danielle da Silva
Published: June 2022

Abstract The objective was to evaluate the effect of different levels of potassium fertilization on the initial growth of forage cactus (Nopalea cochenillifera Salm Dyck) clones. The experiment lasted six months, arranged in a randomized block design, in a 5 x 2 factorial scheme, with five levels of potassium fertilization (0, 250, 500, 750, and 1,000 kg of K2O ha-1) and two forage cactus clones (Little Sweet and Giant Sweet), with four replicates. One cladode was planted per pot (experimental unit) with a capacity of 7 kg of soil (24 x 17 x 23 cm). During the experimental period, the plants' structural characteristics were evaluated, such as plant height and width, length, width, thickness, and perimeter of the cladode, as well as accounting for the number of total cladodes, and in order of appearance. At the end of the experiment, biomass was evaluated to determine the fresh matter (FM) and dry matter (DM) yield of the aerial part and the root system. After determining the DM, the potassium content in the plant tissues was determined. The data were submitted to ANOVA and, if necessary, to the Tukey test at a 5% significance level. The potassium fertilization and the forage palm clones did not exert influences based on the variables evaluated during the experimental conduction. Potassium fertilization does not influence the structural and productive characteristics and the potassium content in the N. cochenillifera clones' initial growth.
Inspecting Pieces, Producing Papers: About Traces and Criminal Expertise Techniques
Authors: Nadai Larissa
Published: June 2022

Abstract This article seeks to unveil the many narrative, graphic and formal layers that give rise to the forensics reports on rape and sexual assault crimes, produced by the Legal Medical Institute of Campinas ( Instituto Médico Legal - IML), between 2004 and 2005. Therefore, I start from the graphic model that shapes these papers – its layout-form – to gradually show the narrative formula contained in them: pieces of flesh . Finally, by following these paths, I intend to show how the criminal materiality of rape and sexual assault is confused with the materiality of the sex of girls, boys and women who are taken care of at this institution.
A importância do reconhecimento social na construção da identidade sexual de mulheres não heterossexuais no sul da Bahia
Authors: Freitas Lorena Rodrigues Tavares de
Published: June 2022

Resumo O objetivo deste artigo é compreender o processo de construção da identidade sexual de 4 mulheres não heterossexuais, universitárias, residentes nas cidades de Ilhéus e Itabuna – BA. Este estudo de caso toma como ponto de partida a participação delas em movimentos estudantis em uma universidade pública da região e busca problematizar o reconhecimento social obtido por meio de relações de amizades construídas por meio desses movimentos, demonstrando a importância do reconhecimento na construção da autoconfiança das entrevistadas.
A agenda portuguesa da descriminalização do aborto à luz do backlash sob as forças políticas liberais e conservadoras
Authors: Monteiro Rosa
Published: June 2022

Resumo Este artigo analisa a agenda política da descriminalização do aborto em Portugal, suas genealogias, agentes, aspetos críticos e resultados. Sublinha o papel dos movimentos de mulheres, da agência nacional para a igualdade, bem como o papel dos partidos políticos. Analisando o recente backlash de 2015, o artigo destaca os riscos de viragens para forças políticas de direita que representa para a agenda feminista e dos direitos das mulheres. Esses riscos parecem ser particularmente severos num contexto de crise financeira e societal, e sob um regime de austeridade, no qual os discursos economicistas e conservadores são bastante aceites.
The Abortion Agenda in Portugal Considering the Recent Backlash under Liberal and Conservative Political Forces
Authors: Monteiro Rosa
Published: June 2022

Abstract This paper analyses the political agenda behind the decriminalization of abortion in Portugal, its genealogy, agents, critical aspects and results. It highlights the role of women’s movements, the National Agency for Equality, and the role of political parties. Analyzing the 2015 backlash it highlights the risks to a feminist and women rights agenda brought by shifts to right-wing political forces. These risks seem to be particularly severe in a context of financial and societal crises, and under an austerity regime, in which economistic and conservative discourses are widely accepted.