bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantifying Severity of Preschool-Aged Children’s Internalizing Behaviors: A Daily Diary Analysis
Authors: Bufferd Sara J. , Olino Thomas M. , Dougherty Lea R.
Published: September 2021

A subset of preschool-aged children meets criteria for impairing and persistent anxiety and depression. However, the overlap between normative emotional development and impairing symptoms complicates assessments of internalizing problems in early childhood. Given the benefits of early identification/prevention and avoiding overpathologizing typical development, empirical information is needed to norm expression of internalizing behaviors. In this 14-day online diary study, 609 primary caregivers of 3- to 5-year-old children reported the frequency of children’s daily separation and social anxiety and depressive behaviors and impairment. Item response theory analyses quantified specific frequencies at which each behavior was psychometrically severe/rare. Patterns varied for each behavior; for example, distress when anticipating separation had to occur at least 10 times and sadness at least 35 times over 14 days to be considered severe. Most social anxiety behaviors had to occur approximately every other day to be considered severe. Parameters did not vary by child age or sex, and behaviors were significantly associated with impairment. These data provide empirical information for refining internalizing behavior assessment in preschool-aged children and can be used as benchmarks by child practitioners to assess the extent to which frequencies fall in the range of developmentally typical behavior versus those that may be more severe.
Improving Outcomes for Families of Children With Medical Needs Known to Child Welfare: A Nurse Care Coordination Program
Authors: Lilly Anne , Cavella Marc , Roper-Lewis Arnesha , Weglarz Mary , Ayala Linda , Cirillo Lilli Alexandra , Greene Mollie , Colabelli Nina , Duggan Anne
Published: September 2021

Children known to child welfare are more likely to have poor health compared to the general population. Most children served by child welfare are served in their own homes. New Jersey implemented the Child and Family Nurse Program (CFNP) to provide nurse care coordination to address the health needs of children who remain in-home. Our study described: 1) families served by CFNP; 2) services provided to these families; and 3) family well-being outcomes. The study focused on the 304 families served by CFNP from 2016 to 2017. We used CFNP data to describe families served and services provided, and family baseline and follow-up surveys to assess change in family well-being over time. Families served by CFNP experienced improvements in family protective factors and health-related quality of life from baseline to follow-up. While more rigorous studies are needed to learn CFNP’s impact, it is a promising approach that merits consideration by state child welfare leaders.
#MeToo on the Canadian Prairies: Raising Awareness of Sexual Assaults and Mental Health in Women Abused by Intimate Partners
Authors: Tutty Leslie M. , Nixon Kendra L.
Published: September 2021

Studies of intimate partner sexual assault (IPSA) and its effects on mental health are limited. This secondary data analysis examines IPSA, a history of child sexual abuse, depression, trauma, mental distress and quality of life in 665 Canadian women, 41% of whom had been sexually assaulted by intimate partners; 53% were sexually abused as children. Women who had experienced any IPSA had significantly higher scores on all Composite Abuse subscales (IPV), mental distress (SCL-10), and depression (CES-D-10). PTSD (PCL) was higher for women with both IPSA and CSA histories. Implications for advocates, clinicians, and researchers are presented.
Analysis of chemical contamination by hazardous drugs with BD HD Check® system in a tertiary hospital
Authors: Valero García Silvia , Centelles-Oria María , Palanques-Pastor Tomás , Vila Clérigues Nieves , López-Briz Eduardo , Poveda Andrés José Luis
Published: September 2021

The presence of contamination in the healthcare work environment by one of the types of hazardous drugs, cytostatics, has been found in multiple international studies. Recent studies and guidelines recommend surface monitoring for risk assessment of healthcare professionals’ exposure. The availability of detection techniques is critical to successfully carry out this type of monitoring. The use of new semi-quantitative techniques allows quicker results. The main objective of this study was to determine the existence of hazardous drugs on the working surfaces in different locations of a tertiary hospital using the BD HD Check® semi-quantitative device. The presence of methotrexate, doxorubicin and cyclophosphamide was analysed at 80, 89 and 82 locations in 10, 13 and 11 clinical units, respectively. A total of 251 samples were analysed. The monitoring results were positive for 13.1% of the analysed samples, with 36.3% of the methotrexate samples, 0% of the doxorubicin samples and 4.9% of the cyclophosphamide samples. Mapping the presence of HD in our hospital has allowed us to evaluate the effectiveness of controls established in the hospital to minimise the exposure of healthcare professionals to hazardous drugs. The speed in obtaining results has enabled immediate corrective actions in cases where contaminated surfaces were detected.
Acceptance of coronavirus disease 2019 vaccination by cancer patients in Cyprus: A cross-sectional study
Authors: Roupa Zoe , Noula Maria , Nikitara Monica , Ghobrial Savoula , Latzourakis Evangelos , Polychronis Giannis
Published: September 2021

Introduction

The acceptance of an individual to be vaccinated following the introduction of a new vaccine is dependent on multiple factors. Governing factors directing one’s decision to be vaccinated against severe acute respiratory syndrome coronavirus 2, however, are currently unknown and the present study aims at researching these factors within the population of cancer patients.

Methods

A cross-sectional self-administered survey was conducted anonymously between 22 January and 12 February 2021, during the second vaccination phase against severe acute respiratory syndrome coronavirus 2 in Cyprus. The data were collected via an online questionnaire which was formerly used by previously conducted studies. The Mann–Whitney U test was applied for the comparison of means between bivariate variables, while the Kruskal–Wallis test was used for the comparison of means in variables with more than two groups. In addition, Spearman correlation coefficients were applied to explore the correlation of continuous variables.

Results

The sample size consisted of a total of 211 cancer patients, 64.9% of which were women with a mean age of 52.6 ± 12.4 years. The findings of the current research indicate a moderate vaccination acceptance among cancer patients ( Μ = 3.3 ± 0.7, R = 1–5).

Conclusion

During the promotion of a vaccine against severe acute respiratory syndrome coronavirus 2 to cancer patients, particular emphasis on specific demographic characteristics, vaccination history and preferred sources of informing the individual are required. In addition, through reviewing the prospective effectiveness and possible outcomes of the specific vaccine according to cancer type and anti-cancer therapy, many of the existing concerns and reservations from cancer patients are expected to be diminished.
Descriptive study of clinical pharmacist interventions in adult hospice and palliative care at a comprehensive oncology center in Jordan
Authors: Salmany Sewar S. , Rayyan Manal , Dabbous Ala'a , Mughrabi Amani EL
Published: September 2021

Introduction

Few studies have evaluated the role of a clinical pharmacist in hospice and palliative care in oncology. We aimed to describe the intervention of a clinical pharmacist in hospice and palliative care at a comprehensive oncology center in Jordan.

Methods

A retrospective descriptive study at a comprehensive oncology center in Jordan between 2006 and 2019. Quantifi® pharmacy documentation system was used to retrieve the clinical pharmacists’ interventions in three hospice and palliative care settings, inpatient hospice and palliative care, outpatient hospice and palliative care clinics and home health care. Where clinical pharmacists document their interventions, significance and acceptance of the interventions by the physician is done using Quantifi®.

Results

Over 13 years, 27,720 documented interventions were retrieved in the three settings of hospice and palliative care: inpatient hospice and palliative care, outpatient hospice and palliative care clinics and home health care setting. The most common reported interventions were drug therapy recommendation/discontinuation (41%), followed by medication reconciliation (21.7%) and patient counseling (16.8%). The medication classes most commonly associated with the hospice and palliative care clinical pharmacist interventions were analgesics (20.9%), antibiotics (19.7%), followed by medications for the nervous system (12.4%). The acceptance rate of the interventions by physicians was around (90%) and 100% of the interventions were considered significant.

Conclusion

Our study showed the high impact of the hospice and palliative care clinical pharmacist in oncology providing the high number of clinical pharmacists’ interventions.
Physico-chemical and microbiological changes during the cabbage hybrid bravo heads fermentation: Salt, temperature and starter culture influence
Authors: Drašković Berger Mirna , Vakula Anita , Tepić Horecki Aleksandra , Peulić Tatjana , Jokanović Marija , Kocić-Tanackov Sunčica , Rakić Dušan , Pavlić Branimir , Blagojev Nevena , Rakić Irena , Šumić Zdravko
Published: September 2021

The influence of temperatures (18, 22 and 26 °C), salt (60, 70 and 80 g/kg) and starter culture (0, 0.025 and 0.050 g/kg) on physico-chemical and microbiological changes during fermentation in cabbage heads were investigated. The experiment was set up in industrial conditions, samples were taken after 0, 5, 12, 27 and 62 days in order to determine the changes in color, texture, biogenic amines content, microbiological parameters, pH, aw, total sugar content, total acidity and salt content. Analysis of variance and Principal component analysis were applied to get a better overview of differences between samples and the similarities between different fermentation conditions. Significant color changes and softening of cabbage tissue did not occurred during the entire fermentation process. Cadaverine was not detected in samples containing starter culture, also the results were in range for maximum allowed putrescine and cadaverine doses for all cabbage samples. Total number of molds increased, contrary to number of yeasts on the last examined day in comparison with raw cabbage sample. Enterobacteriaceae were not detected after 5th fermentation day, while sharp increase of lactic acid bacteria number occurred until 12th day, and on the 12th fermentation day was in range of 7.82 to 9.84 log cfu/g. The fermentation process led to decrease in pH, aw and total sugar content, meanwhile total acidity 0.54%-0.89% and salt content 2.08%-3.19% in the cabbage heads increased, in comparison with raw sample where results for total acidity and salt content were 0.13% and 0.05%, respectively. Additionally, according Principal component analysis, temperature of fermentation had the greatest influence on the fermentation process, followed by the application of starter culture and then concentration of added salt.
The Father, the Son, and the Abuser: The Portrayal of Male Victims of Intimate Partner Homicide in the News Media
Authors: Hanson Kenzie , Lysova Alexandra
Published: September 2021

Media research on intimate partner homicide (IPH) has primarily focused on male perpetrators and female victims. This study analyzed 203 English-language news articles of IPH involving male victims and female perpetrators for the year 2019. Using thematic analysis, we identified two main themes: doubting the victim (who is the victim?) and victim recognition (“he didn’t deserve this”). The findings suggest that male victims of female perpetrated IPH tend to be blamed for their victimization and represented as non-ideal and illegitimate victims in the news media.
Understanding Replication in a Way That Is True to Science
Authors: Haig Brian D.
Published: September 2021

In this article, I critically examine a number of widely held beliefs about the nature of replication and its place in science, with particular reference to psychology. In doing so, I present a number of underappreciated understandings of the nature of science more generally. I contend that some contributors to the replication debates overstate the importance of replication in science and mischaracterize the relationship between direct and conceptual replication. I also claim that there has been a failure to appreciate sufficiently the variety of legitimate replication practices that scientists engage in. In this regard, I highlight the tendency to pay insufficient attention to methodological triangulation as an important strategy for justifying empirical claims. I argue, further, that the replication debates tend to overstate the closeness of the relationship between replication and theory construction. Some features of this relationship are spelt out with reference to the hypothetico-deductive and the abductive accounts of scientific method. Additionally, an evaluation of the status of replication in different characterizations of scientific progress is undertaken. I maintain that viewing replication as just one element of the wide array of scientific endeavors leads to the conclusion that it is not as prominent in science as is often claimed.
Ecological Values Theory: Beyond Conformity, Goal-Seeking, and Rule-Following in Action and Interaction
Authors: Hodges Bert H. , Rączaszek-Leonardi Joanna
Published: September 2021

Values have long been considered important for psychology but are frequently characterized as beliefs, goals, rules, or norms. Ecological values theory locates them, not in people or in objects, but in ecosystem relationships and the demands those relationships place on fields of action within the system. To test the worth of this approach, we consider skilled coordination tasks in social psychology (e.g., negotiating disagreements, synchrony and asynchrony in interactions, and selectivity in social learning) and perception-action (e.g., driving vehicles and carrying a child). Evidence suggests that a diverse array of values (e.g., truth, social solidarity, justice, flexibility, safety, and comfort) work in a cooperative tension to guide actions. Values emerge as critical constraints on action that differ from goals, rules, and natural laws, and yet provide the larger context in which these can function effectively. Prospects and challenges for understanding values and their role in action, including theoretical and methodological issues, are considered.
An Investigation into the Temporal Reproducibility of Tryptophan Metabolite Networks Among Healthy Adolescents
Authors: Oluwagbemigun Kolade , Anesi Andrea , Clarke Gerard , Schmid Matthias , Mattivi Fulvio , Nöthlings Ute
Published: September 2021

Tryptophan and its bioactive metabolites are associated with health conditions such as systemic inflammation, cardiometabolic diseases, and neurodegenerative disorders. There are dynamic interactions among metabolites of tryptophan. The interactions between metabolites, particularly those that are strong and temporally reproducible could be of pathophysiological relevance. Using a targeted metabolomics approach, the concentration levels of tryptophan and 18 of its metabolites across multiple pathways was quantified in 24-hours urine samples at 2 time-points, age 17 years (baseline) and 18 years (follow-up) from 132 (52% female) apparently healthy adolescent participants of the DOrtmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study. In sex-specific analyses, we applied 2 network approaches, the Gaussian graphical model and Bayesian network to (1) explore the network structure for both time-points, (2) retrieve strongly related metabolites, and (3) determine whether the strongly related metabolites were temporally reproducible. Independent of selected covariates, the 2 network approaches revealed 5 associations that were strong and temporally reproducible. These were novel relationships, between kynurenic acid and indole-3-acetic acid in females and between kynurenic acid and xanthurenic acid in males, as well as known relationships between kynurenine and 3-hydroxykynurenine, and between 3-hydroxykynurenine and 3-hydroxyanthranilic acid in females and between tryptophan and kynurenine in males. Overall, this epidemiological study using network-based approaches shed new light into tryptophan metabolism, particularly the interaction of host and microbial metabolites. The 5 observed relationships suggested the existence of a temporally stable pattern of tryptophan and 6 metabolites in healthy adolescent, which could be further investigated in search of fingerprints of specific physiological states. The metabolites in these relationships may represent a multi-biomarker panel that could be informative for health outcomes.
The nonlinear effects of tourism on rural income inequality and urban–rural income inequality: Evidence from China
Authors: Zhang Jiekuan
Published: September 2021

Tourism’s relationship with income inequality is a hot spot in the academic community; however, few studies focus on how tourism shapes rural income inequality, despite its significant role in rural poverty alleviation. This article investigates the nonlinear effects of tourism on urban–rural income inequality and rural income inequality based on data from China’s provincial regions over the period 1995–2018, using the dynamic panel data approach. This study further examines the regional heterogeneity of such effects. The results demonstrate that for the national sample, there exists a significant cubic curve relationship between domestic tourism and rural income inequality. However, inbound tourism’s relationship with rural income inequality is not significant. Besides, there exists an N-shaped Kuznets curve between domestic or inbound tourism and urban–rural income inequality. The effects of tourism on rural income inequality and urban–rural income inequality vary significantly across the eastern, middle, and western regions. From east to middle to west, the significance of inbound tourism’s influence on income inequality decreases gradually. This study also highlights some critical theoretical and practical implications. Unlike prior studies, this article builds the first comprehensive research framework consisting of tourism, rural income inequality, and urban–rural income inequality.
Application of digital child mental health training to improve capacity in majority world countries: Professional perspectives from Turkey and Pakistan
Authors: Vostanis Panos , Eruyar Seyda , Hassan Sajida , AlOwaybil Reem , O’Reilly Michelle
Published: September 2021

Digital technology offers opportunities for child mental health capacity building, which is a priority for Majority World Countries (MWC). The aim of this study was to explore the experiences and perspectives of professionals from different disciplines in Turkey ( n=12) and Pakistan ( n=15), who had completed a two-module digital trauma-informed programme on enhancing practice skills and instigating systemic changes. Interview data were analysed through a coding thematic approach. Participants especially valued the interdisciplinary and holistic approach of the training, and its proposed scaled service model. Digital training, particularly in blended format, can enhance reach and capacity in MWC low-resource settings.
How parents share and limit their child’s access to information about COVID-19: A mixed methods online survey study
Authors: Garcia de Avila Marla A , Carter Bernie , Blake Lucy , Saron Holly , Kirton Jennifer , Protheroe Joanne , Novaes Dayane C , Alencar Rúbia A , Fernandes Teixeira Tatiane R , Bray Lucy
Published: September 2021

This study aimed to understand the role that parents play in sharing or limiting their child’s access to information about coronavirus disease 2019 (COVID-19). A subset of data from an international mixed methods online survey study was analysed to elucidate the findings from Brazil. An online survey, conducted between April and June 2020, gathered closed and open text views from parents of children aged 7–12 years old. Quantitative data were analysed using descriptive statistics. Qualitative open text data were analysed using the three stages of the Bardin content analysis framework: pre-analysis (data organisation and initial full-content reading); exploration of the material (thematic coding to identify major motifs and develop thematic categories) and interpretation (treating the data as significant and valid). The sample consisted of 112 (89%) mothers and 14 (11%) fathers. The analysis of the parents open text resulted in two categories: ‘How parents share information with their children about COVID-19’ and ‘How parents limit information to their children about COVID-19’. Some parents reported adopting an honest and open approach on how they shared information with their children, whilst some parents chose to minimise their child’s access to information about the pandemic over concerns of the mortality related to COVID-19.
Pop-socialism: A new radical left politics? Evaluating the rise and fall of the British and Italian left in the anti-austerity age
Authors: Ward Bradley , Guglielmo Marco
Published: September 2021

This article draws from primary research – including 46 semi-structured interviews – to provide a comparative analysis of Jeremy Corbyn’s leadership of the British Labour Party between 2015 and 2020, and Nichi Vendola’s leadership of the Italian radical left between 2010 and 2015. It is claimed that both cases represent a new form of left politics – which we term pop-socialism – that combines popular-democratic appeals to the ‘people’ with the traditional class-based demands of democratic socialism. This contributes to recent literature on radical left politics and left populism by providing an insight into the underexplored relationship between popular-democratic and class politics. Moreover, the article provides an important empirical account of Corbyn and Vendola’s rapid mobilisation but also their equally abrupt decline.
Impact of alcohol and drug use on bicycle and electric scooter injuries and hospital admissions in the United States
Authors: Namiri Nikan K , Lee Austin W , Amend Gregory M , Vargo Jason , Breyer Benjamin N
Published: September 2021

Introduction

Bicycles and electric scooters (e-scooters) are convenient and accessible means of transportation. Participant safety is contingent on available infrastructure and safe riding practices including not riding while intoxicated. Understanding national prevalence and injury characteristics of bicycle and e-scooter riders who ride while intoxicated may promote awareness campaigns for safe riding practices and decrease morbidity.

Methods

The National Electronic Injury Surveillance System (NEISS) provides national estimates of injuries that present to emergency departments across the United States. We obtained case information on admitting status, body part injured, diagnosis of injury, age, sex, alcohol usage, and drug usage. We then queried NEISS for injuries related to bicycles and e-scooters in 2019.

Results

A weighted total of 270,571 (95% confidence interval (CI): 204,517–336,625) bicycle injuries occurred in the United States during 2019; alcohol and drug use were associated with 7% (95% CI: 6–9) and 2% (95% CI: 2–3) of all injuries, respectively. Twenty-four percent (CI: 18--31) of alcohol- and 29% (95% CI: 20–41) of drug-related bicycle injuries resulted in hospital admissions, compared to 15% (95% CI: 12–17) of non–alcohol- and 15% (95% CI: 13–18) of non–drug-related injuries ( p < .001 and p = .002, respectively). A total of 28,702 (95% CI: 13,975–43,428) e-scooter injuries occurred in 2019; alcohol and drug use were associated with 8% (95% CI: 5–12) and 1% (95% CI: 1–2) of injuries, respectively. Sixty percent (95% CI: 47–72) of alcohol-related e-scooter injuries resulted in head trauma, compared to 28% (95% CI: 24–32) of non–alcohol-related injuries ( p < .001).

Conclusions

Intoxication is associated with increasingly severe injuries, hospital admissions, and head trauma in bicycle and e-scooter riders. The findings support awareness campaigns to educate riders about risky practices, improve non-auto infrastructure, and promote helmet usage.
Sources of information and the use of mobile applications for health and parenting information during pregnancy: Implications for health promotion
Authors: Buchanan Limin , Anderson Emi , MBiostat Huilan Xu , Phongsavan Philayrath , Rissel Chris , Wen Li Ming
Published: September 2021

This study aims to examine the characteristics of pregnant women who used and intended to use mobile applications (apps) for health and parenting information. We used data from a randomised controlled trial, Communicating Healthy Beginnings Advice by Telephone (CHAT), conducted in Australia. Telephone surveys were conducted in 2017 to collect information on women’s demographic characteristics, sources of health and parenting information and willingness to use mobile apps. Multiple logistic regression was used to examine the associations of women’s socio-demographic backgrounds, their mobile apps usage and their willingness to use such apps. Data included 1155 pregnant women in their third trimester. Women from culturally and linguistically diverse backgrounds and with lower income appeared to have lower uptake of mobile apps despite high ownership of smart devices. Development of evidence-based and culturally-adapted mobile apps represent an important opportunity for healthcare providers to optimise maternal and birth outcomes.
Feasibility and Safety of an 8 F Angioseal® Vascular Closure Device for Closure of Large Bore Impella CP® Access
Authors: Zachoval Christian F. , Sedaghat Alexander , Oezkur Mehmet , Tiyerili Vedat , Becher Marc U. , Sinning Jan-Malte , Treede Hendrik , Nickenig Georg , Zimmer Sebastian
Published: September 2021

Purpose:

Percutaneous mechanical circulatory support (pMCS) with the Impella® device is routinely used in cardiogenic shock and high risk percutaneous coronary interventions (PCI). However, safety and feasibility to close the large bore access (LBA) post-hoc remain a challenge.

Materials and Methods:

In patients with planned termination of Impella therapy, corresponding LBA closure was attempted using an undersized AngioSeal® device, which was deployed after insertion of a 0.035 in J-wire through the guidewire access port. Cross-over angiographic visualization before and after deployment as well as in-hospital follow up were performed to assess closure success and screening for short-term adverse events.

Results:

We evaluated 17 patients (68 year old, IQR 58–76, 71% male) in whom 14 F LBA closure after pMCS using the Impella CP® was achieved with an undersized AngioSeal® device. Clinical indication for pMCS was cardiogenic shock in 94% and protected PCI in 6%. Impella CP® devices were withdrawn after a median of 4 days (IQR 3–6 days). Primary hemostasis was achieved in the majority of patients (14/17; 82%) while single cross-over balloon inflation led to hemostasis in the remaining patients. One patient suffered acute ischemia later in the course of the disease, but this was not directly related to the closure device. In this study, no major bleeding or other device-related adverse events were observed.

Conclusion:

The 8 F AngioSeal® vascular closure device has been safely used for removal of the Impella CP® microaxial pump in most cases of predominantly normal weight patients. This technique may be considered feasible for post-hoc LBA closure in the context of pMCS, especially when preclosure options are not suitable or unavailable.
Gender Differences in Neuropsychiatric Symptoms Among Community-Dwelling Mexican Americans Aged 80 and Older
Authors: Milani Sadaf Arefi , Cantu Phillip A. , Berenson Abbey B. , Kuo Yong-Fang , Markides Kyriakos S. , Raji Mukaila A.
Published: September 2021

Background and Objectives

To assess gender differences in prevalence of neuropsychiatric symptoms (NPS) among community-dwelling Mexican Americans ≥80 years.

Research Design and Methods

Using data from Wave 7 (2010–2011) of the Hispanic Established Population for the Epidemiological Study of the Elderly, we analyzed the NPS of 914 participants as determined by the Neuropsychiatric Inventory (NPI) with assessments conducted by their caregivers. Multivariate logistic regression models were used to test the association of individual NPS with gender, adjusting for relevant characteristics.

Results

The average age of our sample was 86.1 years, and 65.3% were women. Over 60% of participants had at least one informant/caregiver reported NPS. After adjustment, women had lower odds than men of agitation/aggression but higher odds of dysphoria/depression and anxiety.

Discussion

Recognizing gender differences in NPS phenotype could help guide development of culturally appropriate NPS screening and treatment programs.
Hybrid Procedure for Coexistence of Coarctation of the Aorta and Aberrant Right Subclavian Artery: A Case Report and Review of the Literature
Authors: Cohen-Mussali Salomon , Leon Monica , Ramírez-Cerda Claudio , Cobos-Gonzalez Ernesto , Valdes-Flores Jaime
Published: September 2021

Background: Coarctation of the aorta (CoA) can either present alone as an isolated condition or in association with other aortic arch or cardiac anomalies. One percent of patients with CoA have concomitant an aberrant right subclavian artery (ARSA). Purpose: We report the case of a 35-year-old woman with uncontrolled hypertension who was found to have CoA and ARSA. Results: The patient was treated successfully using a hybrid procedure comprising ARSA ligation and subclavian to carotid transposition, followed by thoracic endovascular aortic repair. Conclusions: Patients with CoA should be carefully studied, considering the possible coexistence of other congenital aortic arch defects, such as ARSA. Hybrid repair is a safe and effective approach for this condition.
‘Here and There, Then and Now’: Envisioning a Palimpsest Methodology
Authors: Okello Wilson Kwamogi , Duran Antonio
Published: September 2021

Black feminisms challenge Western conceptions of linearity as an optic for understanding the experiences of Black folx in the United States social imaginary. As such, this article centers the understanding that for Black and minoritized folx, historical legacies carry the lingering effects of what may seem over and done with. These tensions converge on what M. Jacqui Alexander (2005) called the palimpsest, or “a parchment that has been inscribed two or three times, the previous text having been imperfectly erased” (Alexander, 2005, p. 190). A framing of time and realities as palimpsestic, or imperfect erasure, suggests that the past is visible and acting upon the present. The potential of a palimpsest methodology rests on the ethical entanglements of the body, memory, and space-time and afterlives with respect to existing tendencies and reliable possibilities. Methodologically, we propose that the palimpsest necessarily reads data and researcher positionalities as woven together, written over, and grappling with one another. In turn, this article intends to pursue embodied research by envisioning the notion of the palimpsest as a methodological tool. To accomplish this, we begin with a brief review of the literature and disciplinary grounds that root the notion of the palimpsest. From there, we discuss the guiding principles for this approach before offering methodological considerations. Against the violence of complicity, temporality, and objectivity, for researchers, a palimpsest approach argues for an assumed responsibility to the work they engage in, the lives they work with, and sites that ground their work.
Eccentric compression behavior of FRP-concrete-steel tubular composite columns
Authors: Zhang Ni , Zheng Chenyang , Zhao Zhongwei , Yang Bo
Published: September 2021

FRP-concrete-steel tubular (FCS) composite columns are composed of the external tube, the internal steel tube, and the concrete between both tubes. They have been attracting the attention of many researchers due to their high ductility, lightweight, resistance to corrosion, and easiness of construction. However, there are few studies on FRP-concrete-steel tubular composite columns under eccentric load. To investigate the behavior of composite columns under the eccentric compression, a non-linear analysis program for FCS composite columns was compiled. The program was verified by existing tests, and the influences of eccentricity, FRP tube wall thickness, steel tube wall thickness, steel tube radius, slenderness ratio, and concrete strength grade on the eccentric compression performance were systematically analyzed. The results showed that the calculated results were in good agreement with the experimental results. It showed that the program can accurately reflect the deformation of FCS composite columns under various loads and estimate the ultimate load of FCS composite columns under eccentric compression. The eccentric ultimate load increased with the decrease of eccentricity and slenderness ratio, and with the increase of FRP tube wall thickness, steel tube wall thickness, and concrete strength grade. The ultimate eccentric load decreased with the increase of steel tube radius, but when the steel tube wall thickness reached a certain thickness, the ultimate eccentric load of FCS composite columns increases with the increase of steel tube radius. The conclusion can provide reference for the practical application of the structure.
Angiographic patterns and temporal changes of arterial lesions in Behcet’s disease
Authors: Choi Su Jin , Koo Hyun Jung , Kang Joon-Won , Ahn Soo Min , Oh Ji Seon , Kim Yong-Gil , Lee Chang-Keun , Yoo Bin , Hong Seokchan
Published: September 2021

Background

Behcet’s disease (BD) can entail vascular involvement in various forms including aneurysm. We evaluated the angiographic patterns and changes in arterial lesions over time in BD patients with arterial involvement.

Methods

We reviewed the medical records of BD patients diagnosed with arterial lesions between 1995 and 2018. Angiographic patterns were categorized as stenosis, occlusion, dilatation, or aneurysm. Patients were divided according to symptom duration (<5, 5–10, >10 years). Cox proportional-hazards model was used to evaluate the risk factors for vascular progression.

Results

47 BD patients had arterial involvement in the following patterns: aneurysm ( n = 31), stenosis ( n = 17), dilatation ( n = 13), and occlusion ( n = 8). Aneurysm (70.8%) was the most common pattern in 24 patients with short (<5 years) symptom duration. Stenosis was more common (50.0%) in 12 patients with longer symptom durations (>10 years). In 23 patients with follow-up imaging (median, 5.7 years), eight (34.8%) developed 11 new lesions: stenosis ( n = 5), dilatation ( n = 1), and aneurysm ( n = 5). One stenotic lesion progressed to occlusion, and two dilated lesions progressed to aneurysms. Lower extremity involvement and methotrexate use were associated with arterial progression, with hazard ratios of 5.716 ( p = 0.029) and 0.101 ( p = 0.049), respectively.

Conclusion

In BD patients with arterial involvement, aneurysm was the most common pattern in earlier stages of BD, while stenosis was more common in later stages of BD. Methotrexate use was associated with lower risk of arterial lesion progression.
An efficient and metal-free synthesis of 5,7-dimethylcyclopentenon[2,3-c]coumarin
Authors: Yerramreddy Thirupathi Reddy , Yiannikouris Alexandros
Published: September 2021

An improved and alternative method for the metal-free synthesis of 5,7-dimethylcyclopentenon[2,3- c]coumarin as a possible useful aflatoxin template in the production of molecular imprinting polymers with affinity toward natural aflatoxin molecules is reported. A synthesis of 5,7-dimethylcyclopentenon[2,3- c]coumarin from 3,5-dimethoxyphenol via a Pechmann condensation involved five steps and represents an alternative commercially viable approach over existing synthetic protocols in the literature. Operational simplicity, inexpensive key raw materials, short reaction times, and excellent yields are remarkable features of this approach. The aflatoxin template was provided in 55%–67% overall yield from 3,5-dimethoxyphenol with >99% purity, evaluated by high-performance liquid chromatography, 1H NMR, 13C NMR, high-resolution mass spectrometry, and liquid chromatography–mass spectrometry.
Effectiveness of corticosteroids on chest high-resolution computed tomography features of COVID-19 pneumonia
Authors: Calabrese Cecilia , Pafundi Pia Clara , Mollica Mariano , Annunziata Anna , Imitazione Pasquale , Lanza Maurizia , Polistina Giorgio , Flora Martina , Guarino Salvatore , Palumbo Cristiana , Fiorentino Giuseppe
Published: September 2021

Objective:

The aim of our study was to assess the effect of a short-term treatment with low-moderate corticosteroid (CS) doses by both a quantitative and qualitative assessment of chest HRCT of COVID-19 pneumonia.

Methods:

CORTICOVID is a single-center, cross-sectional, retrospective study involving severe/critical COVID-19 patients with mild/moderate ARDS. Lung total severity score was obtained according to Chung and colleagues. Moreover, the relative percentages of lung total severity score by ground glass opacities, consolidations, crazy paving, and linear bands were computed. Chest HRCT scores, P/F ratio, and laboratory parameters were evaluated before (pre-CS) and 7–10 days after (post-CS) methylprednisolone of 0.5–0.8 mg/kg/day.

Findings:

A total of 34 severe/critical COVID-19 patients were included in the study, of which 17 received Standard of Care (SoC) and 17 CS therapy in add-on. CS treatment disclosed a significant decrease in HRCT total severity score [median = 6 (IQR: 5–7.5) versus 10 (IQR: 9–13) in SoC, p < 0.001], as well in single consolidations [median = 0.33 (IQR: 0–0.92) versus 6.73 (IQR: 2.49–8.03) in SoC, p < 0.001] and crazy paving scores [mean = 0.19 (SD = 0.53) versus 1.79 (SD = 2.71) in SoC, p = 0.010], along with a significant increase in linear bands [mean = 2.56 (SD = 1.65) versus 0.97 (SD = 1.30) in SoC, p = 0.006]. GGO score instead did not significantly differ at the end of treatment between the two groups. Most post-CS GGO, however, derived from previous consolidations and crazy paving [median = 1.5 (0.35–3.81) versus 2 (1.25–3.8) pre-CS; p = 0.579], while pre-CS GGO significantly decreased after methylprednisolone therapy [median = 0.66 (0.05–1.33) versus 1.5 (0.35–3.81) pre-CS; p = 0.004]. CS therapy further determined a significant improvement in P/F levels [median P/F = 310 (IQR: 235.5–370) versus 136 (IQR: 98.5–211.75) in SoC; p < 0.001], and a significant increase in white blood cells, lymphocytes, and neutrophils absolute values.

Conclusion:

The improvement of all chest HRCT findings further supports the role of CS adjunctive therapy in severe/critical COVID-19 pneumonia.
Prevalence and mortality of COVID-19 are associated with the L55M functional polymorphism of Paraoxonase 1
Authors: Saadat Mostafa
Published: September 2021

Introduction

Accumulating evidence recommends that infectious diseases including coronavirus disease 2019 (COVID-19) are often associated with oxidative stress and inflammation. Paraoxonase 1 ( PON1, OMIM: 168,820), a member of the paraoxonase gene family, has antioxidant properties. Enzyme activity of paraoxonase depends on a variety of influencing factors such as polymorphisms of PON1, ethnicity, gender, age, and a number of environmental variables. The PON1 has two common functional polymorphisms, namely, Q192R (rs662) and L55M (rs854560). The R192 and M55 alleles are associated with increase and decrease in enzyme activity, respectively.

Objective

The present study was conducted to investigate the possible association of rs662 and rs854560 polymorphisms with morbidity and mortality of COVID-19.

Methods

Data for the prevalence, mortality, and amount of accomplished diagnostic test (per 106 people) on 25 November 2020 from 48 countries were included in the present study. The Human Development Index (HDI) was used as a potential confounding variable.

Results

The frequency of M55 was positively correlated with the prevalence (partial r = 0.487, df = 36, p = 0.002) and mortality of COVID-19 (partial r = 0.551, df = 36, p < 0.001), after adjustments for HDI and amount of the accomplished diagnostic test as possible confounders.

Conclusions

This means that countries with higher M55 frequency have higher prevalence and mortality of COVID-19.
Choroidal thickness and retinal nerve fiber layer analysis in acute systemic brucellosis
Authors: Zor Kürşad Ramazan , Arslan Gülen Tuğba , Yıldırım Biçer Gamze , Küçük Erkut , İmre Ayfer , Ödemiş İlker , Kayabaş Üner
Published: September 2021

Introduction

This study aims to detect changes in choroidal thickness and retinal nerve fiber layer (RNFL) thickness in acute stage brucellosis.

Methods

Fnewly diagnosed patients with acute brucellosis and 19 healthy individuals as control group were included in the study. Choroidal thickness and RNFL thickness were measured using the Spectral Domain Cirrus OCT Model 400 (Carl Zeiss Meditec, Jena, Germany) for each participant in the patient and control group.

Results

In the brucella group, in the right eyes, the mean nasal choroidal thickness was 272.77 ± 50.26 μm ( p = 0.689), the mean subfoveal choroidal thickness was 321.14 ± 33.08 μm ( p = 0.590), the mean temporal choroidal thickness was 278.86 ± 48.84 μm ( p = 0.478), and the mean RNFL thickness was 90.43 ± 8.93 μm ( p = 0.567). In the left eyes, the mean nasal choroidal thickness was 282.29 ± 48.93 μm ( p = 0.715), the mean subfoveal choroidal thickness was 316.79 ± 39.57 μm ( p = 0.540), the mean temporal choroidal thickness was 284.93 ± 50.57 μm ( p = 0.392), and the mean RNFL thickness was 92.64 ± 8.95 μm ( p = 0.813).

Conclusion

No difference was found between the control and the brucella groups regarding to all choroidal regions and RNFL thickness.
“My baby should feel no wronged!”: Digital fandoms and emotional capitalism in China
Authors: Yin Yiyi
Published: September 2021

As the digitalization of fandom and the fandomization of digital platforms have both been discussed recently, this study intends to analyze how the logic of digital fandom was formalized in fans’ everyday media practices. Specifically, the study examines the new trends of digital fandoms in China from the perspective of emotional capitalism. Based on long-termed participated observation and semi-structural interviews, the study argues that the emotional engagement of digital fan practice was legitimated by the incarnation of virtual fan objects, the datafication of emotional labor, and the re-imagination of multi-social relationships.
Inheriting Mary Ainsworth and the Strange Situation: Questions of Legacy, Authority, and Methodology for Contemporary Developmental Attachment Researchers
Authors: Spies Ruan , Duschinsky Robbie
Published: September 2021

Mary Ainsworth’s legacy continues to shape the social and developmental sciences well after her death. The Ainsworth Strange Situation Procedure has, for decades, not only provided the underpinning methodology of attachment research, but also the frame of reference for theory. This has produced conditions where, as in psychoanalysis, debates about the future of the paradigm also entail a struggle to claim and negotiate the legacy of a founding figure. To date, historians have only looked at attachment research up to the 1980s. Interviews with 15 leading contemporary attachment researchers revealed Ainsworth’s importance to later research, but also laid bare the challenges of claiming her inheritance in responding to the current challenges facing this area of research.
The Lived Experience of Early Marriage in Jordan: The Perspective of Adolescent Girls and Young Women
Authors: Mrayan Lina , Obeisat Salwa
Published: September 2021

Child or early marriage, primarily due to cultural factors, continues as a tradition and seems to be a growing phenomenon in Jordan. This research explores the lived experience of early marriage from the perspective of adolescent girls and young women. A qualitative research design and in-depth face-to-face interviews in the Arabic language were conducted with 36 female subjects, married before the age of 18 and all newlyweds, married for less than 3 years. Six major themes emerged from the interviews to describe the experience of the participants: “Feeling remorse about getting married early”; “Loss of authority and feeling powerless”; “Reasons behind early marriage”; “Feeling pressure to have the first baby”; “Early marriage and pregnancy health consequences”; and “The positive aspects of an early marriage.” The lived experience revealed in this study confirm the overall negative effect of girls entering marriage at a young age, Early marriage is a violation of human rights, and robs girls of their childhood, education, work, and other life choices, in addition to the reported adverse psychological and physical effects.
Patient-Reported Outcomes Following Surgery for Lumbar Disc Herniation: Comparison of a Universal and Multitier Health Care System
Authors: Ayling Oliver GS , Ailon Tamir , Craig Michael , Dea Nicolas , McIntosh Greg , Abraham Edward , Jacobs W Bradly , Johnson Michael G , Paquet Jerome , Yee Albert , Hall Hamilton , Bailey Chris , Manson Neil , Rampersaud Y Raja , Thomas Kenneth , Fisher Charles G
Published: September 2021

Study Design

Ambispective cohort study.

Objective

Canada has a government-funded universal health care system. The United States utilizes a multitier public and private system. The objective is to investigate differences in clinical outcomes between those surgically treated for lumbar disc herniation in a universal health care and multitier health system.

Methods

Surgical lumbar disc herniation patients enrolled in the Canadian Spine Outcome Research Network (CSORN) were compared with the surgical cohort enrolled in the Spine Patients Outcome Research Trial (SPORT) study. Baseline demographics and spine-related patient-reported outcomes (PROs) were compared at 3 months and 1 year post-operatively.

Results

The CSORN cohort consisted of 443 patients; the SPORT cohort had 763 patients. Patients in the CSORN cohort were older (46.4 ± 13.5 vs 41.0 ± 10.8, P < .001) and were more likely to be employed (69.5% vs 60.3%, P = .003). The CSORN cohort demonstrated significantly greater rates of satisfaction after surgery at 3 months (87.2% vs 64.8%, P < .0001) and 1 year (85.6% vs 69.6%, P < .0001). Improvements in back and leg pain followed similar trajectories in the two cohorts, but there was less improvement on ODI in the CSORN cohort ( P < .01). On multivariable logistic regression, the CSORN cohort was a significant independent predictor of patient satisfaction at 1-year follow-up ( P < .001).

Conclusions

Despite less improvement on ODI, patients enrolled in CSORN, as part of a universal health care system, reported higher rates of satisfaction at 3 months and 1 year post-operatively compared to patients enrolled within a multitier health system.