bluuebunny/crossref_metadata_2025 huggingface dataset:
Resonance modes in moiré photonic patterns for twistoptics
Authors: Alnasser Khadijah , Kamau Steve , Hurley Noah , Cui Jingbiao , Lin Yuankun
Published: March 2021

Twistronics has been studied for manipulating electronic properties through a twist angle in the formed moiré superlattices of two dimensional layer materials. In this paper, we study twistoptics for manipulating optical properties in twisted moiré photonic patterns without physical rotations. We describe a theoretic approach for the formation of single-layer twisted photonic pattern in square and triangular lattices through an interference of two sets of laser beams arranged in two cone geometries. The moiré period and the size of unit super-cell of moiré patterns are related to the twist angle that is calculated from the wavevector ratio of laser beams. The bright and dark regions in moiré photonic pattern in triangular lattices are reversible. We simulate E-field intensities and their cavity quality factors for resonance modes in moiré photonic pattern in square lattices. Due to the bandgap dislocation between the bright and dark regions, the resonance modes with very high quality-factors appears near bandgap edges for the moiré photonic pattern with a twist angle of 9.5 degrees. At the low frequency range, the resonance modes can be explained as Mie resonances. The cavity quality factor decreases for resonance modes when the twist angle is increased to 22.6 degrees.
Prevalence and antibiotic resistance profile of Listeria spp. associated with seafoods from fish catchment areas in Kerala, India
Authors: Vrinda Menon K. , Sunil B. , Latha C.
Published: March 2021

Background and Aim: Listeria monocytogenes is a ubiquitous, intracellular pathogen which has been implicated as a cause of several foodborne outbreaks. This study aimed to generate information on the prevalence and antibiotic resistance profile of Listeria species isolated from seafood.

Materials and Methods: A total of 400 samples of fresh fish, 100 samples of dry fish and 200 samples each of crustaceans and mollusks were collected from the fish catchment areas. All the samples were subjected to isolation and identification of Listeria spp. by two-step enrichment in UVM broth and plating on selective agar media (PALCAM) and then subjected to molecular characterization. L. monocytogenes isolates obtained during the study were subjected to serotyping by multiplex polymerase chain reaction. The isolates were also subjected to antibiotic sensitivity test.

Results: The prevalence of L. monocytogenes in seafoods in the present study was 0.55%. The isolates of L. monocytogenes were found to possess all virulence genes, namely, iap, hlyA, actA, prfA, plcA, and inlA. All the isolates belonged to serotype 4b. The occurrence of Listeria innocua was found to be more and was detected in 16.77% of seafoods samples. Antibiotic sensitivity test revealed that all isolates were resistant to cefixime but were sensitive to almost all other commonly used antibiotics.

Conclusion: The presence of Listeria spp. in raw seafood samples augments the need for implementation of good hygienic practices during the handling and processing of seafoods to safeguard the health of the consumers.
El acoso sexual en la universidad: la visión del alumnado
Authors:   Facultad de Ciencias de la Educación, Universidad de Santiago de Compostela, España, Alonso-Ruido Patricia , Martínez-Román Rosana ,   Facultad de Educación y Trabajo Social, Universidad de Vigo, España, Rodríguez-Castro Yolanda ,   Facultad de Educación y Trabajo Social, Universidad de Vigo, España, Carrera-Fernández María Victoria ,   Facultad de Educación y Trabajo Social, Universidad de Vigo, España
Published: March 2021

Introducción/objetivo: El acoso sexual es una de las violencias que más debe preocupar a la comunidad educativa, por ello, el objetivo de este estudio consiste en analizar los conocimientos, las percepciones y las actitudes de los y las estudiantes universitarios hacia el acoso sexual. Método: Desde un enfoque cualitativo se han realizado diez entrevistas individuales a estudiantes (seis alumnas y cuatro alumnos) y ocho grupos de discusión heterogéneos formados por 67 estudiantes. Todos pertenecientes a una universidad de carácter público situada en el noroeste de España. Resultados: El alumnado tiene pocos conocimientos sobre el acoso sexual y, además, no recibe formación que le otorgue las herramientas que le permitan identificarlo y combatirlo. Asimismo, la mayoría de los/as participantes expresa que el acoso sexual es habitual en el entorno académico, pero que está invisibilizado. A través de sus propias palabras se identifica que perciben actitudes permisivas hacia el acoso sexual por parte de los/as docentes y de la universidad, considerando que no hay una verdadera implicación para intervenir en las situaciones de acoso. Conclusiones: Es necesario que la universidad se comprometa a implementar estrategias de prevención e intervención, con el propósito de identificar, sancionar y erradicar todas y cada una de las formas de violencia, incluido el acoso sexual.
Analysis of the impact of COVID-19 on the coupling of the material flow and capital flow in a closed-loop supply chain
Authors: Duan W. , Ma H. , Xu D.S.
Published: March 2021

The complex and changeable external social and economic environment has a significant impact on the sustainable development of the closed-loop supply chain. In particular, the occurrence of uncertain emergencies increases the risk of interruption of the closed-loop supply chain, making it insufficient to analyze its complex changes from the perspective of material flow alone. Based on this analysis, the paper constructs a closed-loop supply chain material flow and capital flow coupling system composed of manufacturers, sellers and recyclers to explore the impact of material flow sudden interruption on the closed-loop supply chain system when an uncertain emergency occurs. In this paper, based on the closed-loop supply chain system coupled with logistics and capital flow, a system dynamics simulation model was established by using Vensim simulation software to analyze the impact of COVID-19 epidemic on manufacturers, sellers and recyclers under five scenarios. The results show that when COVID-19 outbreaks occur, the material flow of each main enterprise in the closed-loop supply chain is more easily influenced than the capital flow. At the same time, it can be found that the recyclers in the main enterprises of the closed-loop supply chain are more easily influenced by the material flow. The model constructed in this paper has applicability and can be used for related studies of closed-loop supply chain under other emergencies, but the scene design should be carried out according to the characteristics of emergencies themselves.
A dynamic job-shop scheduling model based on deep learning
Authors: Tian W. , Zhang H.P.
Published: March 2021

Ideally, the solution to job-shop scheduling problem (JSP) should effectively reduce the cost of manpower and materials, thereby enhancing the core competitiveness of the manufacturer. Deep learning (DL) neural networks have certain advantages in handling complex dynamic JSPs with a massive amount of historical data. Therefore, this paper proposes a dynamic job-shop scheduling model based on DL. Firstly, a data prediction model was established for dynamic job-shop scheduling, with long short-term memory network (LSTM) as the basis; the Dropout technology and adaptive moment estimation (ADAM) were introduced to enhance the generalization ability and prediction effect of the model. Next, the dynamic JSP was described in details, and three objective functions, namely, maximum makespan, total device load, and key device load, were chosen for optimization. Finally, the multi-objective problem of dynamic JSP scheduling was solved by the improved multi-objective genetic algorithm (MOGA). The effectiveness of the algorithm was proved experimentally.
Multi-objective automated guided vehicle scheduling based on MapReduce framework
Authors: Shi W. , Tang D.B. , Zou P.
Published: March 2021

During material handling processes, automated guided vehicles (AGVs) pose a path conflict problem. To solve this problem, we proposed a multi-objective scheduling model based on total driving distance and waiting time, and used the A* path planning algorithm to search the shortest path of AGV. By using a speed control strategy, we were able to detect the overlap path and the conflict time. Additionally, we adopted an efficient MapReduce framework to improve the speed control strategy execution efficiency. At last, a material handling system of smart electrical connectors workshop was discussed to verify the scheduling model and the speed control strategy combined with the MapReduce framework is feasible and effective to reduce the AGV path conflict probability. The material handling system could be applied in workshop to replace manual handling and to improve production efficiency.
A conceptual model for measuring the competency level of Small and Medium-sized Enterprises (SMEs)
Authors: Oztemel E. , Ozel S.
Published: March 2021

Small and Medium-Sized Enterprises (SMEs) are of major importance to developing countries. SMEs are the main drivers to strengthen society in sustaining economic growth and development. Governments provide various support programs to improve their industrial power and to increase the number of enterprises in the market. The enterprises must be assessed and suitable funds should be provided to those in need, to achieve an effective support program in the most efficient way.This requires implementing an assessment methodology based on a predefined set of scientific criteria. The current literature is comprehensive enough to assess the healthiness of the enterprises concerning strategic, technologic, financial as well as intellectual competencies but on the other hand, it lacks of an assessment model. This study aims to introduce a general framework for sustaining an effective assessment methodology for SMEs to eliminate this gap. The proposed model measures five different types of competencies such as Technological Competency, Strategic Competency, Financial Competency, Intellectual Competency, R&D and Innovation Competency. These competencies are to put forth the conditions in which the enterprises are running accurately. A real-life case study is conducted to ensure the baseline of the model to be implemented. The governmental organizations may utilize the model for sustaining their support role effectively to SMEs.
A new management approach based on Additive Manufacturing technologies and Industry 4.0 requirements
Authors: Patalas-Maliszewska J. , Topczak M.
Published: March 2021

Nowadays, it is necessary to formulate and implement a development strategy in manufacturing enterprises, in line with the assumptions of the Industry 4.0 concept. In this context, a gap in the research has been observed in effective management methods, in order to gain a competitive advantage through the implementation and use of Additive Manufacturing (AM) technologies. The main purpose of the study is to build a new approach to management, based on the implementation of new AM technologies and good practice. This paper uses the detailed literature studies and results from the empirical research of some 250 Polish manufacturing enterprises; this material contains a sample thereof, processed into a new approach. The major contributions of the work are as follows: (1) identification of current management areas in which manufacturing companies focus their activities, in the context of Industry 4.0, (2) the establishment of the correlation between gaining a competitive advantage and implementing AM technologies in the context of Industry 4.0, (3) Defining the so-called AM4.0CARD as a new management approach, based on AM technologies and the requirements of Industry 4.0. Managers of manufacturing enterprises, thanks to the use of the proposed approach, may take a strategic decision, regarding the implementation of AM technologies, due to the possibility of forecasting the impact of such an investment on the improvement of the company's competitive advantage.
Three-phase modeling and optimization of benzene alkylation in commercial catalytic reactors
Authors: Danesh Donya , Farsi Mohammad , Rahimpour Mohammad Reza
Published: March 2021

The main object of this research is heterogenous modeling of benzene alkylation in three phase reactors based on the mass and energy balance equations by coupling the kinetic and equilibrium models and optimization the process conditions to enhance production capacity. In the first step, the alkylation reactors are simulated considering a three-phase model including heat and mass transfer resistances in the solid catalyst, gas and liquid phases. To prove the accuracy of developed model and adopted assumptions, the simulation results are compared with the plant data. Based on the simulation results, the benzene conversion and ethylbenzene selectivity in the alkylation reactors are 15.03 and 94.60% at the conventional condition. In the second step, considering the temperature of inlet streams to the reactors as decision variables, an optimization problem is formulated to maximize the ethylbenzene production rate as the objective function. Based on the simulation results, applying optimal condition on the system improves the ethylbenzene production by 1.33% at the same ethylene conversion compared to the conventional condition.
Respiratory viral infections and associated neurological manifestations
Authors: Hosseini Shirin , Michaelsen-Preusse Kristin , Korte Martin
Published: March 2021

Respiratory viruses as a major threat to human and animal health today are still a leading cause of worldwide severe pandemics. Although the primary target tissue of these viruses is the lung, they can induce immediate or delayed neuropathological manifestations in humans and animals. Already after the Spanish flu (1918/20) evidence accumulated that neurological diseases can be induced by respiratory viral infections as some patients showed parkinsonism, seizures, or dementia. In the recent outbreak of COVID-19 as well patients suffered from headache, dizziness, nausea, or reduced sense of smell and taste suggesting that SARS-CoV2 may affect the central nervous system (CNS). It was shown that different respiratory viral infections can lead to deleterious complications in the CNS by a direct invasion of the virus into the brain and/or indirect pathways via proinflammatory cytokine expression. Therefore, we will discuss in this review mechanisms how the most prevalent respiratory viruses including influenza and coronaviruses in humans can exert long-lasting detrimental effects on the CNS and possible links to the development of neurodegenerative diseases as an enduring consequence.
Feasibility Analysis of Multimedia Technology Applied in Musical Drama Teaching Class—Taking the Teaching Practice of the Township Version of “Tang Xianzu” as an Example
Authors: Zhang Qing , Li Xiaorong
Published: March 2021

In today’s fast-developing society, information technology is widely used in various teaching fields, which has a major impact on education and teaching in all aspects. In the classroom teaching of musical dramas, the application of multimedia technology has greatly broadened the teaching philosophy of musical drama teachers and constantly changed the teaching mode of musical drama teaching classrooms. It also made music teachers have to improve their multimedia technology to adapt to modern teaching facilities. Multi-channel surround sound is an inevitable trend in the development of audio-visual technology and a perfect embodiment of art and technology. Multi-channel surround system is applied to multimedia teaching, which brings students a stronger sense of space, positioning, and layering. The impact of audition can fully stimulate students’ enthusiasm and interest in learning. Based on the mature multimedia teaching technology, this article studies the audio production processing technology related to it in detail. On this basis, the multi-channel surround sound of streaming media is also tracked and analyzed. The difference between the two determines the theoretical and technical gap between the two formats and elaborates on the procedures and steps for surround sound production. This article takes the teaching practice of the township version of “Tang Xianzu” as an example to design a multi-channel surround sound system. Multi-channel surround sound technology was introduced into the multimedia software production of the musical drama teaching class. A leap in the production level of multimedia software. It injects vitality into music quality education and broadens the application range of modern educational technology.
IACMI–The Composites Institute Efforts in Current and Post–COVID-19 Manufacturing Era—Innovations and Sustainability
Authors: Vaidya Uday , Hopkins John
Published: March 2021

Institute for Advanced Composites Manufacturing Innovation (IACMI)–The Composites Institute comprises 150 industry members making up the supply chain from material suppliers; Tiers 1, 2, and 3 original equipment manufacturer (OEM)s and fabricators; academia; and national laboratories. The institute is addressing the needs for medical systems support in response to the coronavirus 2019 (COVID-19) crisis and the recovery of the U.S. composites industry and connected manufacturing supply chains. The impact of the current and post-COVID response by IACMI and its partners extends across health care, automotive, transportation, construction, infrastructure, aerospace, sports, marine, and industrial sectors. Sustainability and circular economy of advanced materials and manufacturing play a key role in overall reduced embodied energy. This technical note provides a summary of IACMI efforts in response to COVID-19 and outlook for the post-COVID era with a focus on sustainable advanced materials and manufacturing.
The effect of music therapy on chronic pain, quality of life and quality of sleep in adolescents after transthoracic occlusion of ventricular septal defect
Authors: Lin Ze-Wei , Liu Jian-Feng , Xie Wen-Peng , Chen Qiang , Cao Hua
Published: March 2021

Objective: To investigate the effect of music therapy on chronic pain, quality of life, and quality of sleep in adolescent patients after transthoracic occlusion of ventricular septal defects.
Methods: Patients were divided into 2 groups based on whether they received music therapy: a control group and a music group. The music group received 30 minutes of music therapy every day for 6 months after surgery. Patients in the control group received standard treatment and had 30 minutes of quiet time every day for 6 months after surgery. The short-form McGill pain questionnaire (SF-MPQ), the SF-36 scale and the Karolinska Sleep Questionnaire (KSQ) was used as the evaluation tool for chronic pain, quality of life, and quality of sleep, respectively.
Results: In terms of the degree of postoperative chronic pain, the Pain Rating Index (PRI) emotion item score in the SF-MPQ evaluation of the music group was significantly lower than that of the control group (1.6 ± 1.1 versus 2.2 ± 0.9). The role emotional (RE) scores of the SF-36 in the music group were significantly higher than that in the control group (77.35 ± 18.55 versus 42.66 ± 22.63). KSQ scores were significantly higher in the music group than in the control group for sleep status (4.1 ± 1.0 versus 3.3 ± 0.9), falling asleep (3.9 ± 1.1 versus 3.1 ± 1.0), and not feeling refreshed by sleep (3.6 ± 1.3 versus 2.7 ± 0.9) (P < .05).
Conclusion: This study preliminarily showed that music therapy could effectively reduce patients’ chronic pain and improve quality of life and sleep after surgery. These results suggest that music therapy may be an essential therapy worth considering in managing patients’ postoperative recovery after cardiovascular surgery.
Magnetoresistive Properties of Multilayer Film Systems Based on Permalloy and Silver
Authors: Pazukha I.M. , Shuliarenko D.O. , Dolgov-Gordiichuk S.R. , Odnodvorets L.V.
Published: March 2021

In this paper, the experimental investigation focuses on the magnetoresistive properties of nanosized film systems. Their structure changes from layered to granular due to transition from bilayer FM/NM (FM is a ferromagnetic material, NM is a nonmagnetic material) to [FM/NM]n multilayer film at a constant total thickness of samples. As ferromagnetic and nonmagnetic materials were chosen permalloy Ni80Fe20 (Py) and Ag, respectively. It was demonstrated that the shape of the field dependences of magnetoresistance depends on the number of bilayer Py/Ag. For as-deposited [Py/Ag]n/S at n = 8, 16, the transition from the antiferromagnetic ordering of magnetic moments to ferromagnetic one occurs under an external magnetic field. As a result, the resistivity of the samples reduced, and the giant magnetoresistive effect was realized. The increase of the number of bilayers repeats from 2 to 16 at the unchanged total thickness of the system leads to the growth of the magnetoresistance from 0.1 % to 0.35 %. During annealing up to 600 K, the magnetoresistive effect is reduced, but it does not disappear completely
Investigation of The Effects of Temperature on Physical, Mechanical And Electrical Conductivity Properties in AISI 310S Austenitic Stainless Steel
Authors: Özlü Torun Handan , Taşdemir Vedat , Kerli Süleyman
Published: March 2021

In our study, annealing was done to AISI 310S stainless steel at 800 °C. The effects of these annealing on structural, morphological, mechanical and electrical conductivities were investigated. From XRD results, it has been observed that the material is austenite and cubic in nature. SEM analysis has shown that the surface of AISI 310S steel changes with temperature. The tensile test of the material was made and it was observed that the tensile strength of the material decreased with the effect of temperature. In addition, the conductivity behavior of AISI 310S steel was measured with four probe technique depending on heat treatment. As a result of the measurements, it was observed that the resistance value increased and the conductivity value decreased in the heat treated material.
Dose periférica em radioterapia: comparação entre diferentes equipamentos aceleradores lineares e mesmo equipamento com diferentes energias de fótons
Authors: Derenevick Josiane , Mariano Leandro , Motim Vitoria , Reway Adriana , Riani Otavio , Soboll Danyel , Malthez Anna Luiza Metidieri Cruz
Published: March 2021

A dose de radiação fora do campo de tratamento de radioterapia pode ser uma preocupação clínica. Portanto, um método para predizer com precisão as doses periféricas recebidas pelos tecidos e a avaliação adequada das doses é necessário para a proteção radiológica de pacientes em tratamentos de radioterapia. O objetivo deste trabalho foi avaliar a dose recebida em áreas periféricas fora da área alvo para tratamentos com feixes de fótons de 6 MV e 15 MV de dois aceleradores lineares diferentes, usando um simulador antropomórfico, e assim comparar os valores obtidos entre os dois equipamentos e entre diferentes energias no mesmo equipamento. Embora os equipamentos e cuidados durante o planejamento busquem minimizar as doses fora da região de tratamento, observamos experimentalmente que mesmo usando tamanho de campo relativamente pequeno e a mesma dose, diferenças nas doses periféricas são observadas, considerando fótons da mesma energia de diferentes equipamentos aceleradores e fótons com energias diferentes empregadas no mesmo equipamento acelerador linear.
Modelagem computacional da dispersão atmosférica aplicada a um reator modular de pequeno porte
Authors: Curzio Rodrigo Carneiro , Neto Alberto Texeira , Moura Bruno da Silva , Talon João Domingos , Lopes Thomaz Jacintho , Bonfim Carlos Eduardo Santos , Cardoso Domingos D´Oliveira , Gavazza Sérgio , Morales Rudnei Karam , Gomes Renato Guedes
Published: March 2021

Este trabalho descreve a modelagem computacional de dispersão atmosférica decorrente de acidente radiológico hipotético em reator modular de pequeno porte (SMR), cuja potência é de 16 MWe (50 MWt). Utilizou-se o software SCALE para modelar o núcleo com três regiões de enriquecimento do combustível, a 4%, 5% e 20%, e obter atividades dos radionuclídeos oriundos de reações nucleares durante o burnup, após 2 anos de operação. Foi escolhida a cidade de Humaitá-AM para instalação do SMR, onde informações sobre condições meteorológicas foram coletadas para identificação da classe de estabilidade atmosférica predominante. Dentre os radionuclídeos do inventário, considerou-se a contribuição do Cs-137 para simulação, usando-se o código HotSpot, das doses totais efetivas (TEDE) recebidas e da concentração, ambos em função da distância do evento. Os resultados sugerem que a partir de 3,1 km do núcleo, as doses estão abaixo da referência para indivíduo do público. A TEDE máxima calculada foi de 3,6 Sv, a 34 m do termo fonte, diminuindo com o tempo e distância, e seguindo o modelo Gaussiano de dispersão. Quanto mais instáveis as condições meteorológicas, maior a TEDE, a uma menor distância do reator. Sugere-se ainda que, para atenuação referente às doses acima desse limiar normativo, próximo ao núcleo, poderá ser dimensionada uma blindagem simples de 75 cm de concreto ordinário ou um arranjo multilaminar composto de 6,4 cm de chumbo e 15 cm de concreto ordinário, relativos à contenção. A pesquisa concluiu que o reator não oferece riscos para operação, considerando os dados assumidos na simulação.
Otimização da dose e da qualidade da imagem em mamografia digital usando a razão contraste-ruído
Authors: Almeida Claudio Domingues , Peixoto João Emílio
Published: March 2021

Em mamografia, a otimização das doses é importante devido ao grande número de mulheres que realizam exames para a detecção precoce do câncer de mama. Além disso, nas duas últimas décadas foram introduzidas tecnologias digitais. Diversos estudos mostram que a dose na mamografia computadorizada CR pode ser superior à da mamografia convencional, indicando a necessidade de sua otimização. O objetivo deste trabalho é apresentar um procedimento usando a razão contraste-ruído (CNR) na otimização da dose e da qualidade da imagem em mamografia digital. O processo de otimização em mamografia digital tem início com a determinação da CNR alvo (CNRalvo). Ela é definida como o valor de CNR que permite atingir o limiar de contraste mínimo de 23% para os discos de 0,1 mm de diâmetro no simulador CDMAM. A CNRalvo é estimada a partir da análise, do limiar de contraste em função da CNR medidos com várias técnicas radiográfica e variadas espessuras de PMMA. A seguir, o sistema do mamógrafo de controle automático das técnicas radiográficas para as diversas espessuras de mama deve ser ajustado de modo a se obter sempre a CNRalvo e doses glandulares médias (DGM) que não ultrapassem os níveis aceitáveis. A aplicação deste procedimento de otimização mostrou que, em uma amostra de 162 pacientes, foram observadas diferenças estatisticamente significativas entre as médias da DGM e da CNR (p < 0,05) quando comparadas com uma amostra de 152 pacientes antes da otimização. Houve uma redução de 14,5% da DGM e a qualidade das imagens clínicas foi mantida.
Determination of uranium and thorium in water for human consumption in the county of Angra dos Reis
Authors: Gonçalves Mariana Ferreira , Ferreira Ana Cristina de Melo , Carvalhal Amanda Balassiano
Published: March 2021

Studies indicate that the presence of uranium and thorium radionuclides in the environment are of great importance in monitoring radiation levels. Humans can have a direct or indirect exposure. The radiological impact for the members of the population living in Angra dos Reis - RJ was evaluated using environmental monitoring data of uranium and thorium in the waters for human consumption of the county of Angra dos Reis. Monitoring data showed concentrations much lower than the guidelines based on the maximum permitted value of uranium in waters for consumption established by CONAMA. Thorium is the most significant radionuclide. The public that lives in the county of Angra dos Reis is not exposed to the radiation that would result in a radiological impact.
Estudo das propriedades de atenuação de materiais para desenvolvimento de um simulador de tireoide-pescoço
Authors: Da Silva Tayrine Moratelli , Soares Alexandre Barbosa , De Lucena Eder Augusto , Dantas Ana Letícia Almeida , Mendes Bruno Melo , Dórea Márcia de Melo , Romani Eric Cardona , Dantas Bernardo Maranhão
Published: March 2021

A estimativa da atividade retida no corpo humano por meio de medidas in vivo requer o uso de fatores de calibração obtidos com simuladores físicos-antropomórficos. A confecção de simuladores utilizando-se tecnologias de impressão 3D é uma opção economicamente viável. Contudo são necessários estudos prévios para selecionar os materiais tecido-equivalentes ideais a serem utilizados, considerando o coeficiente de atenuação de massa como principal critério de avaliação. Neste contexto, foram realizadas séries de medições com uma fonte padrão pontual de 133Ba, variando-se o tipo e espessura do material atenuador. Conclui-se que, para a faixa de energia avaliada, o ABS apresentou-se como o material mais adequado para esta aplicação.
Stability in the production and transport of 177Lu labelled PSMA
Authors: Wieczorek Villas Boas Cristian Antonio , Pereira Dias Luís Alberto , Nakamura Matsuda Margareth Mie , Bortoleti de Araújo Elaine
Published: March 2021

The prostate cancer is the second most prevalent disease among men in Brazil, moreover PSMA therapy could change this scenario and its perspectives. IPEN-CNEN is the Brazilian industrial radiopharmacy center that produces radiopharmaceuticals for therapy. The production of 177Lu-PSMA-617 was evaluated in batches until 37 GBq and showed that the combination of ascorbate buffer, adequate radioactive concentration and freezing promoted the stability of the radiopharmaceutical for 48 hours, enabling transport of 177Lu-PSMA-617 to distant regions of the country.
Profiling European countries on COVID–19 prevalence and association with non–pharmaceutical interventions
Authors: Tallon José M. , Gomes Paulo , Bacelar–Nicolau Leonor
Published: March 2021

Introduction It is essential to understand, on a large geographical scale, the dimension of the COVID–19 pandemic by identifying the most affected countries, knowing that all the world is suffering an unusual disruption regarding several health impacts, but also heavy economic, financial and social effects. A key role is reserved to Data Science to understand the present and to deepen a prospective analysis at COVID–19 day after. Objective The main objective of the present study is to describe the COVID–19 prevalence in EU and five other OECD countries using five epidemiological variables. Secondly their association with non–pharmaceutical measures taken in some countries to control and attenuate the evolution of the epidemic was analyzed. Methods The COVID–19 study covers twenty–six EU countries and additionally Switzerland, Norway, Turkey, Israel and United Kingdom. Five epidemiologic variables were analyzed by 100.000 inhabitants at the beginning of May 2020: total number of cases, total number of deaths, total number of active cases, total number of critical or serious cases and total number of tests. Also, eight non–pharmaceutical measures were selected for association purposes. A multivariate statistical exploratory approach with principal components, hierarchical and non–hierarchical (k–means) cluster analyses was applied. Results A COVID–19 prevalence typology of four country clusters was identified regarding EU countries and five OECD countries on early May. In the two clusters, with a total of ten countries where the pandemic seemed to evolve more seriously, different patterns regarding the number of tests are observed. Two other clusters, with 12 and 9 countries, show an intermediate or low prevalence but differences in testing patterns. For EU countries of both clusters more affected, COVID–19 containment strategies were studied considering three modalities of implementation timing for eight non–pharmaceutical measures. The three different behaviors mirrored the clusters findings. Countries previously classified into cluster 1 appear together again, as do countries belonging to cluster 2. In spite of a common behavior for some measures, generally countries of cluster 2 implemented other interventions later in time. Sweden is a “special case”, taking just a few of these measures, most of them later than other countries.
Effect of physical exercises on anthropometric parameters, blood pressure and heart rate of young people and adults in Matola city–Mozambique
Authors: Sousa Manjate José Luís , Chavane Félix Salvador , Nhantumbo Leonardo Lúcio
Published: March 2021

Introduction: physical inactivity is a risk factor for chronic non-communicable diseases, causing morbidity and mortality and weight gain in the economy of nations. Objective: to analyze the effect of combined physical exercises on anthropometric and hemodynamic parameters in young and adults people in Cidade da Matola. Methodology: 22 subjects from 23 to 60 years old (8 female and 14 male) were randomly selected in 2017. The anthropometric assessment consisted of weight, height, BMI and waist circumference. Hemodynamic variables were evaluated with an Omron M3-HEM-7131-E tensiometer. The sample performed combined physical exercises for three consecutive months. Using SPSS, 20.0, at 95% CI, the non-parametric WILCOXON test was applied to examine the effect of physical exercises on the variables of interest. Results: globally, weight and BMI increased over the course of the intervention, however without statistical differences, on the other hand, height, WP, SBP, DBP and HR differed statistically: P=(0.019; 0.008; 0.048; 0.006; 0.000) respectively. After analyzing the sex, only male individuals registered statistically significant differences for WP, DBP and HR: P=(0.023; 0.006; 0.000) respectively. The age range of individuals aged ≥ 36 years revealed a significant effect of the intervention on the variables WP, DBP and HR: P=(0.022; 0.042; 0.001) respectively. Conclusions: although the sample size was small, globally, the effect of the intervention on the variables of interest was notorious, especially in Blood Pressure, Heart Rate and Waist Perimeter.
Integrated evidence strategy and drug development efficiency
Authors: Tang Zhongwen
Published: March 2021

Drug development has many moving parts. Traditionally they are handled in a more sequential and segmented way. This has served us well due to relatively slow pace of drug development. As the pace of drug development becomes faster and faster, we need to think more in a holistic way. This is especially important due to the advancement of new technologies, which has upended the way how we generate and analyze data. We present a framework to identify integrated evidence opportunities in drug development and demonstrate these opportunities using some real examples.
Obstetric and perinatal outcomes in teenage pregnancy: a literature review
Authors: G Rey , L Paller , F Feldman , W Lauria
Published: March 2021

Pregnancy during adolescence continues to be a frequent situation, mostly in developing countries. Maternal age is a key element to be taken into account when managing obstetric patients, as it is related with obstetric and perinatal outcomes. We conducted a literature review to address the obstetric results of pregnancy in teenage mothers. We reviewed articles for the last 5 years in different databases including ‘Pregnancy’, ‘Teenager’, ‘Adolescent’, ‘Complications’ and ‘Outcomes’ as key words. We obtained 2260 articles after the initial search, but only 28 met the inclusion criteria and were therefore reviewed. Most studies were excluded for not clearly specifying one of more groups of teenage patients, lacking comparison of these groups with no-teenage patients, or not addressing the obstetric outcomes of those pregnancies. The outcomes were divided into complications of pregnancy, childbirth, puerperium and neonatal complications. We found that there is an association between young maternal age and preterm birth, pre-eclampsia/eclampsia, fetal growth restriction and stillbirth, among others. For the newborn we found outcomes such as low APGAR scores and admission to intensive care were more frequent in teenage mothers. We conclude that maternal age is an important feature, as there are several obstetric and perinatal compications that are more frequent in teenage mothers than in other age groups.
Music as medicine during the sars-COV-2 (COVID-19) quarantine: spreading art not fear
Authors: Castillo-Ramírez Rogelio Edgar
Published: March 2021

In December 2019, in Wuhan (Hubei, China), a novel severe acute respiratory syndrome coronavirus could be identified (SARS-CoV-2). The need of home isolation to avoid getting the infection and to avoid its spread, have been associated with fear and other psychological consequences in population of affected countries. Music has demonstrated its positive complementary effect in management and improvement of anxiety, depression, pain and other clinical and social situations associated with negative effects in well-being and quality of life. To date, there are no clinical trials that examine directly the relation between music interventions and improvement of negative emotions for people in quarantine but based on previous research we know that it could be employed as an innocuous and safe complementary intervention to help people to alleviate these feelings. Since the pandemic was declared, musicians have taken different instruments and have even used their own voice to play live music from their balconies or even in the street, showing their solidarity and attempts to encourage their neighbors and other people nearby not to give up against COVID-19.
Towards relation extraction from Arabic text: a review
Authors: AlArfaj Abeer
Published: March 2021

Semantic relation extraction is an important component of ontologies that can support many applications e.g. text mining, question answering, and information extraction. However, extracting semantic relations between concepts is not trivial and one of the main challenges in Natural Language Processing (NLP) Field. The Arabic language has complex morphological, grammatical, and semantic aspects since it is a highly inflectional and derivational language, which makes task even more challenging. In this paper, we present a review of the state of the art for relation extraction from texts, addressing the progress and difficulties in this field. We discuss several aspects related to this task, considering the taxonomic and non-taxonomic relation extraction methods. Majority of relation extraction approaches implement a combination of statistical and linguistic techniques to extract semantic relations from text. We also give special attention to the state of the work on relation extraction from Arabic texts, which need further progress.
Prevalence of dyslipidemia among climacteric women
Authors: de Vargas Juliana Granzotto , Miecinikovsski Renata , Theodoro Heloisa , De Lorenzi Dino Roberto Soares , Noorzada Omarwalid , Giane Mendes Karina
Published: March 2021

Background: The climacteric phase implies metabolic and hormonal changes that might lead to adverse effects, such as dyslipidemia and cardiovascular risks. Objective: Determine factors associated with the prevalence of dyslipidemia among climacteric women treated in a reference clinic in southern Brazil. Method: Cross-sectional study with 550 women aged 40–65 years treated in a clinic specialized in climacteric therapies and gynecologic surgeries. A precoded and pretested standardized survey with questions about socioeconomic, demographic, behavioral and reproductive features was applied. Laboratory tests needed to define lipid profiles were the analysis of HDL cholesterol, total cholesterol, and triglycerides. Multivariate analysis (p<0.05) was used in the evaluation of data. Results: 550 climacteric women were evaluated. Elevated prevalence of dyslipidemia (83.8%) was found. The group presenting the largest number of dyslipidemic women was the group aged 56–65 years (92.5%). There was no significant association between the occurrence of dyslipidemia and menopausal state. Multivariate analysis revealed that dyslipidemias were 11% more prevalent in women aged 56–65 years (RP 1.11; CI95% 1.01 to 1.21 p=0.03) and 16% more frequent among women with three or more gestational periods (p=0.04). The prevalence of dyslipidemia was also higher among obese women than among the eutrophic ones, however, the significance level remained in a boundary zone (PR 1.12; CI95% 1.00 to 1.26 p=0.06). Conclusion: A higher prevalence of dyslipidemia was found among women with multiple pregnancies, something that may be linked to hormonal and metabolic issues, as well as dietary issues during pregnancy. The menopausal state was not associated with the occurrence of dyslipidemia in this study. Possibly, the aging process and its metabolic changes —more than the menopausal state itself— is the main factor associated with dyslipidemia during the climacteric years
A comprehensive review on the nutritional and therapeutical aspects of Stevia rebaudiana bertoni
Authors: Nathalie Escutia-Lopez Karina , Pardo Ma Elena Sanchez , Escobedo Rosalva Mora
Published: March 2021

In late years there has been an increase of scientific evidence that supports the use of Stevia rebaudiana Bertoni (S. rebaudiana) as an alternative to sucrose and artificial sweeteners. In addition to its utility in different industries, S.rebaudiana contains various chemical components with potential benefits for human health such as polyphenols, chlorophylls, carotenoids, among others, which can be extracted for the production of nutraceuticals and functional foods. So far no adverse effects on human health have been proven after ingestion and favorable results have been documented when S.rebaudiana or its derivates are included in treatments against diabetes, certain types of cancer, glucose intolerance, obesity, dental cavities, among others. The purpose of this review is to provide an overview of the clinical, chemical and biochemical literature that presents evidence of the beneficial role of Stevia rebaudiana Bertoni and its metabolites in health promotion properties, as well as its relevance in the pharmaceutical and food industries
Remote detection of music influence with physical sensor
Authors: G Korotkov Konstantin
Published: March 2021

Goals and objectives of the study: The goal of this paper was to study the possibility of remote detection of electronic music influence with a physical sensor. Study design: Bio-Well technology with a special environmental sensor was used in the study. This sensor was developed for the analysis of the electromagnetic fields and was shown to respond to the changed in the environmental parameters. Signal of a sensor was detected for an hour in the background mode after this music was turned on for 20 minutes, and then after-effect was detected for about one hour. In experiment 5 different files of the modern electronic music “Yippi Wave 3.0” (https://yippiweb.com/what-is-wave) in *wav format and several files of Handel music have been used. Results: The statistically significant changes of sensor parameters to “Yippi Wave 3.0” music were detected in several time-series, while no response to Handel music. Conclusions: This study should be considered a pilot study and the results are preliminary. We need to conduct experiments with different sources of both acoustic and electromagnetic signals and the possibility of their registration by the Bio-Well device
Determining optimum period of withholding irrigation for inducing maturity of sugarcane (Saccharum spp. hybrid) in Southern Ethiopia
Authors: Ashagre Semu Yetaferu , Ashagre Yetaferu
Published: March 2021

Withholding irrigation before harvesting is important for inducing maturity in sugarcane. The study was carried out to determine the optimum period of withholding irrigation for inducing maturity in sugarcane in southern Ethiopia. Field experiments were conducted on two sugarcane varieties, N Co 334 and B 52 298 by five treatments of withholding irrigation periods for 20, 30, 40 50 and 60 days in randomized complete block design at the crop age of 11.3 months during 2014-15. The data on soil moisture content, top to bottom ratio of Brix in cane juice by hand refractometer, Brix, pol, purity and reducing sugars percent juice, and recoverable sugar percent cane, estimated sugar yield were recorded. Error variances for all characters except top to bottom ratio of Brix and reducing sugars in canes in experiments of both varieties were homogeneous and thus the data were also analyzed in split-plot design with varieties as the main plot and withholding irrigation period (WIP) treatments as subplots. The soil moisture percent differed at different WIPs with lowest at WIP for 60 days. Quality characters, top to bottom ratio of Brix in juice, Brix, pol or sucrose, purity, and sugar recovery percent cane increased significantly with the increase in WIPs, being highest at 50 and 60 days. Reducing sugars percent juice declined significantly with lowest at WIPs for 60 days. Estimated sugar yield increased significantly with the maximum at WIP for 50 and 60 days. The optimum period for withholding irrigation was 50 to 60 days for inducing maturity in sugarcane if not offset by rains. It was, therefore, suggestive that the irrigation could be withheld to sugarcane crop of about 12 months for 50 to 60 days but the quality of sugarcane should be determined before harvesting for obtaining maximum sugar yield in southern Ethiopia
Case study on the environmental impacts of the design, construction and operation of a storage, treatment, utilization (recovery/recycling) and/or waste disposal end of electrical and electronic equipment (WEEE) in the company Recover SAS NEIVA
Authors: Rodriguez Sanchez Nina Isabella , Rivera Garcia Yerson Camilo
Published: March 2021

For the evaluation of the environmental impact of the design, construction and operation of a plant storage, treatment, utilization (recovery/recycling) and/or disposal of waste electrical and electronic equipment (WEEE) for the company to recover Neiva SAS game the provisions of environmental legislation in the Republic of Colombia and studies on the subject. Then a diagnosis was made of environmental zoning of the area of ​​direct influence (Barrio Reinaldo Matiz); Based on the characterization of strategic development plans; carried out the environmental impact assessment by reference to the methodology proposed by Fernandez,1 for environmental management zoning exclusion areas were established, Environmental impacts associated with the implementation of the project had a rating of compatible severe, however, all negative impacts had a maximum rating of moderate, this shows the lesser degree of alteration that generates the design, construction and operation of a plant storage, processing, utilization (recovery/recycling) and/or disposal of (WEEE) given the characteristics of the area where take place, so the salient negative impacts are pollution particulate matter (air) pollution emission (air), solid waste pollution (soil), and positive are proper handling WEEEs (waste), training,awareness and acceptance of the community for a better management of RAEEs (sociocultural) and conservation of the environment (sociocultural).