bluuebunny/crossref_metadata_2025 huggingface dataset:
ДЕТЕРМІНАНТИ СИСТЕМИ ОХОРОНИ ЗДОРОВ’Я В ПРОБЛЕМАТИЦІ ЗБАЛАНСОВАНОГО РОЗВИТКУ
Authors:   Donetsk National Technical University, Ягельська Катерина
Published: March 2021

The issue focuses on the health care system as a key element of the structure of the sustainable development economy. The first stage of the study was to determine the factors and initial conditions for building an effective health care system in Ukraine. It is argued that the initial conditions for building the effective health care system in countries vary widely and are characterized by varying strengths of challenges and threats. It is concluded that Ukraine’s economic development is largely determined by global determinants along with national ones, among them the most influential are: capital, success and effectiveness of structural reforms, effective changes in industrial policy, transformations in public consumption, investment-innovation and technological policy, institutional development infrastructure of small and medium business. The systemic problems of the domestic economy and the health care system have been identified. The planned financing of health care elements for 2021 has been analyzed and its weaknesses have been identified. Emphasis is placed on the contradictions between the priorities of the state budget and its coverage. The problem of potential sources of expansion of general expenses is considered. The basic elements that are necessary for the development of the health care system of Ukraine in modern conditions have been identified. The content of economic, ecological and social components of the transformation of the health care system, which are realized through the active participation of the state, private sector and society in the development of the medical sphere of the country, is revealed. The environmental component in the aspect of health care is revealed through crisis determinants that qualitatively change the indicators of health system efficiency. A set of determinants of health care functioning on a global scale is described, among which economic, political, ecological threats, educational crisis; threats of global terrorism are singled out. The basic requirements to the health care system are defined and substantiated on the basis of the analysis of the health care market of Ukraine, the analysis of the purposes of the health care system functioning and the purposes of sustainable development in Ukraine. The content of the basic requirements for the health care system, which corresponds to the formulated basic principles of the effective health care system, is revealed. The priorities for formulating the requirements for the health care system in the conditions of sustainable development of economic relations have been formulated.
СУЧАСНІ ТЕНДЕНЦІЇ ІНВЕСТУВАННЯ ГОСПОДАРСЬКОЇ ДІЯЛЬНОСТІ ПІДПРИЄМСТВ
Authors:   Donetsk National Technical University, Волкова Юлія
Published: March 2021

Research of the current state and structure of capital investments both in Ukraine in general and in the Donetsk region in particular, in the period 2011 - 2019, identification of negative trends and prospects, indication of certain proposals for attracting investment resources. Methodology. The research methodology is generally based on the methods of system analysis, generalization and comparison. Results.The main provisions in the formulation of the concept of "investment" were indicated, the classification structure of investments on various grounds is given. The dynamics of changes in the volume of capital investment in the economy of Ukraine, and, in particular, in the economy of Donetsk region for the period 2011 - 2019, which in turn allowed to determine the causes of fluctuations. The analysis of the structure of capital investments by sources and types of economic activity of Donetsk region is carried out, certain conclusions are made about the changes that took place in the studied period. Recommendations for improving the efficiency of investment attraction are provided. Scientific novelty. The main factors that constrain the attraction of investment in the economy of Ukraine and in the economy of Donetsk region are given. The most priority branch of the region’s economy for investors has been identified, and a structural analysis of capital investments in the region’s economy has made it possible to find out at the expense of which funds the enterprises are renewing their fixed assets. There are some suggestions for effective investment. Prospects for investing in the national economy are substantiated. Practical significance. The results of the study form a practical basis for finding additional sources of investment in economic activity of industrial enterprises on a sustainable basis.
ОСОБЛИВОСТІ ДЕРЖАВНО-ПРИВАТНОГО ПАРТНЕРСТВА В МЕДИЧНІЙ СФЕРІ В УМОВАХ ЗАБЕЗПЕЧЕННЯ СТАЛОГО РОЗВИТКУ
Authors:   Donetsk State University of Management, Байрак Оксана
Published: March 2021

The article summarizes scientific discussions on the use of public-private partnership in the health sector and concludes that it is relevant as a tool for sustainable development of the country, regions and individual industries. The structural elements of public-private partnership have been identified. Based on the systematization of literary sources on approaches to the definition of public-private partnership, it was found that the content of the category "public-private partnership" is revealed through the complementarity of the project and institutional approaches, as well as in aspects of strategic development and stylistic reception in a broad sense, as a result of which the author's interpretation of the category public-private partnership in the medical field. The types of public-private partnerships as a tool for sustainable development of the country and its regions are systematized and the feasibility of integrating various projects is substantiated. The main features of public-private partnership in the medical field are revealed, revealing the specifics of partnership between the state and the private sector as an economic category. Key words: public-private partnership, private sector, medical sphere, healthcare, sustainable development. It is proved that the use of the term public-private partnership in scientific and practical activities is associated with the introduction of a new economic form of interaction between the state and the private sector for effective attraction and use of financial resources and organizational opportunities of business in limited investment resources. The author explored the variety of forms and areas of partnership between the state and business, which makes it a universal tool for solving government problems in priority areas of the economy and increasing the country's competitiveness, ensuring sustainable national and regional growth and sustainable economic relations.
МАРКЕТИНГОВІ КОМУНІКАЦІЇ ЯК ЧИННИК ПІДВИЩЕННЯ КОНКУРЕНТОСПРОМОЖНОСТІ ПІДПРИЄМСТВА
Authors:   Donetsk National Technical University, Панченко Ганна
Published: March 2021

It is determined that domestic enterprises of today are under constant competitive pressure, due to the growing uncertainty and variability of the marketing environment, the acceleration of STP, the evolution of society's needs. It is shown that marketing communications should reduce the impact of negative external and internal influences on the functioning of the business due to the ability to increase its competitive advantages and maintain their advantageous position in an unstable economy. It has been proven that an effective integrated marketing communication strategy is potentially important for the success of the organization, as it is able to provide future competitive advantage. It is substantiated that marketing communications are essential sources of existence of the economic system in general and the enterprise in particular. It is determined that at the present stage of development of economic relations in the world and in Ukraine the concept of integrated marketing communications is becoming popular. Recommendations for the formation of a generalized model of integrated marketing communications are given. It is shown that the scientific approach to the management of marketing communications has a positive effect on the development and effectiveness of decisions, so it is worth evaluating the effectiveness of integrated marketing communications. It is proved that the latest modern strategy of integrated communications management is based on planned management decisions in the field of optimization of integrated marketing communications, which demonstrate the image and reputation of the company in society. The expediency of introduction of the model of integrated marketing communications into the enterprise competitiveness management system is substantiated. Recommendations for the formation of a model of integrated marketing communications form a scientific and practical basis for conducting analytical and forecasting research in terms of substantiating the best ways to further increase the competitiveness of the enterprise in global and domestic markets.
Estimation of the biological efficiency of prospective dominant strains of bacteria in the rhizosphere of spring barley
Authors:   National University of Life and Environmental Sciences of Ukraine, Kiroiants M. , Patyka M. ,   National University of Life and Environmental Sciences of Ukraine, Patyka T. ,   National University of Life and Environmental Sciences of Ukraine
Published: March 2021

An important task of modern agricultural production is the creation of new environmentally friendly agricultural technologies aimed at increasing the productivity of crops. Spring barley is an important forage crop, which occupies a significant place in the balance of concentrated feed. Therefore, our study is quite relevant today, given the trend towards the transition to organic farming and the development of biological fertilizers. The aim of the study was to determine the efficiency of inoculation with dominant strains of rhizosphere bacteria Phyllobacterium ifriqiyense 1 and Bacillus methylotrophicus 10 seeds of spring barley and physiological parameters of growth and development of the culture in model conditions. The task of the study is to determine the titer of viable bacteria, exposure of spring barley seeds in bacterial suspension, accounting for the growth of spring barley plants and fixing its biometric parameters after bacterization; determination of physiological parameters of plant growth and development in model conditions. Research methods – microbiological (direct calculation of viable colony-forming units using Goryaev's camera). Indicators of photosynthetic activity of the leaf were determined using the biophysical method of induction of chlorophyll fluorescence by a portable device "Floratest". The results of studies – the strain Phyllobacterium ifriqiyense 1 showed the maximum biological effect on the growth of test culture of barley (including dilution of culture fluid). It was found that treatment with bacterial suspensions of Phyllobacterium ifriqiyense 1 and Bacillus methylotrophicus 10 promotes the activation of the functions of the photosynthetic apparatus of barley plants in the laboratory. Prospects – rhizosphere microorganisms are important components of the environment in the early stages of ontogeny of cereals, so the use of dominant inoculating bacteria has scientific and practical significance in the optimization of agricultural production technologies.
Estimation of coarse woody debris stocks in forest ecosystems of Slobozhansky national nature park
Authors:   Institute of Agroecology and Nature Management of NAAS, Furdychko O. , Chornobrov O. ,   Institute of Agroecology and Nature Management of NAAS, Solomakha I. ,   Institute of Agroecology and Nature Management of NAAS, Tymochko I. ,   Institute of Agroecology and Nature Management of NAAS, Bezrodnova O. ,   V. N. Karazin Kharkiv National University
Published: March 2021

Dead wood is an important component of forest ecosystems. It performs a number of environmental functions. Coarse woody debris includes standing dead trees, fallen dead trees, fragments of fallen trees (trunks), branches (fragments of branches), and rough tree roots. It is a substrate and habitat for living organisms, including a number of species of mosses, lichens, fungi, invertebrates, as well as birds and mammals. Woody detritus plays an important role in the biological cycle of substances and energy, and carbon deposition, is a source of nutrients. Therefore, the study of quantitative and qualitative features of dead wood, in particular on protected areas, is a considerable nowadays problem. The aim of the work is to estimate identified by forest inventory stocks of dead wood in forest ecosystems of Slobozhansky NNP by categories, as well as to analyze the distribution of its volumes in stands of dominant tree species and forest types. The estimation of coarse woody debris stocks was performed based on forest inventory data of Slobozhansky National Nature Park conducted by Ukrainian State Project Forestry Production association “Ukrderzhlisproekt”. Data from 493 forest stands of nine tree species were analyzed. The stock of the following fractions of coarse woody debris was studied: standing dead wood, fallen (downed) dead wood. Data analysis was performed using MS Excel 2016 software. It was found that the total area of forest stands in which standing or downed dead wood was found during forest inventory was 2149.8 ha, or 47.5% of the total forest area of NNP. The total stock of coarse woody debris was 19478 m3, more than 95% of which is concentrated in the stands of Scots pine (Pinus sylvestris L.) (78.8%) and pedunculate oak (Quercus robur L.) (16.6%). Standing dead wood prevailed (62.1%) fallen dead wood (37.9%) in the structure of dead wood volume. The volume of dead wood was in the range of 5–50 m3∙ha–1, and on average in studied forest ecosystems in which it was found was 9.1 m3∙ha–1. In Scots pine forest stands coarse woody debris was found on an area of 1703.5 hectares with total stock of 15355 m3, consists of standing dead trees (9952 m3, 64.8%) and fallen dead wood (5403 m3, 35.2%). The volume of dead wood in forest stands was 5–50 m3∙ha–1, on average – 9.0 m3∙ha–1. In pedunculate oak stands coarse wood debris was found on an area of 384.7 hectares with a total stock of 3224 m3, consists of standing dead wood (1469 m3, 45.6%) and fallen dead wood (1755 m3, 54.4%). The volume of dead wood in forest stands was 5–20 m3∙ha–1, on average – 8.4 m3∙ha–1.
Change of physical indicators of cherry fruit depending on treatment by polysaccharide compositions during storage
Authors:   Uman National University of Horticulture, Vasylyshyna O.
Published: March 2021

Currently, the problem of environmental pollution has become important, so the development of biodegradable films based on polysaccharide coatings, which could completely replace plastic is relevant. The purpose of research conducted with cherries of the varieties Alpha and Memory Artemenko, grown at the research station of pomology named after LP Simirenko IS NAAS − to establish the effect of treatment (100 mg/l) with a solution of salicylic acid; (1 %) chitosan with (100 mg/l) salicylic acid; (1 %) chitosan; on physical indicators: microstructure, density and weight loss of cherry fruits during storage at a temperature of 1 ± 0.5°C and relative humidity of 95±1 %. As a result of the conducted researches it was established that pre-treatment of cherry fruits with 100 mg/l with salicylic acid and 1 % chitosan affected the microstructure of mesocarp. The density of cherries of the varieties Alpha and Memory Artemenko, after storage decreased by 40.8 % and 45.2 %. In fruits treated with salicylic acid, the losses were 29.2 and 31.4 %, and 1 % solution of chitosan with salicylic acid −18,2 % and 12,6 %. Fruits pre-treated with a solution of salicylic acid have a lower weight loss of 3,5−3,4 %, and with the combined action of salicylic acid and chitosan – 2,7−3,0 %. The prospect of further research is to determine the physical changes of cherry fruits of different varieties by pre-treatment with a solution of salicylic acid and chitosan.
Winter wheat (triticum aestivum l.) mutation depression under gamma-rays action
Authors:   Dnipro State Agrarian and Economics University, Nazarenko M. , Lykholat Y. ,   Oles Honchar Dnipro National University, Savosko V. ,   Kryvyi Rih State Pedagogical University
Published: March 2021

The purpose of our investigation was to identify the features of the depressive effects of the aftereffect of different doses of gamma-rays on winter wheat varieties of local breeding in terms of germination, survival, morphometry, yield. The parameters of germination and survival, the passage of the main phases of ontogenesis in winter wheat plants of French varieties (Courtiot and Gallixe) at the first generation were studied. The influence of mutagenic depression on parameters of yield structure (morphometry of mature plants) was established and the level of their variability was estimated too. In 2019 - 2020, experiments were conducted in the research fields of the research center of the Dnieper State Agrarian and Economic University. The experiments used seeds of Courtiot and Gallixe varieties, irradiated with gamma rays in doses of 100, 150, 200, 250, 300 Gy. Control was dry seeds. The variety Gallixe can be classified as resistant to gamma-rays, the variety Courtiotwas corresponded to high-sensitive. Parameter of germination and survival were directly correlated with increasing dose, with a dose of 200 Gy already semi-lethal, a dose of 250 Gy for variety Courtiot was sublethal, 300 Gy doze full-lethal, for the variety Gallixe sublethal was 300 Gy dose by which almost no plant material was obtained. Such parameters as plant height, weight of grain from the main spike and weight of thousand grains, partially (except for doses of 100-150 Gy) weight of grain from the plant reliably reproduce the mutagenic depression. Depression of the variety is affected by the dose of mutagen more than the genotype of the variety; the plant height parameter clearly demonstrates mutagenic depression. According to the results of factor and discriminant analysis as indicators affected by genotype-mutagenic interaction should be used germination and survival, pollen sterility, plant height, grain weight per spike, weight of thousand grains. Doses of 100 - 200 Gy are optimal for further use to obtain mutations; it is possible to use a dose of 250 Gy for the variety Gallixe.
Effect of vitamin and mineral supplements on antioxidant protection indices in new zealand white breed rabbit
Authors:   Bila Tserkva National Agricultural University, Tsekhmistrenko S. , Fedorchenko M. ,   Bila Tserkva National Agricultural University
Published: March 2021

Recently, scientific approaches to the classification of the antioxidant system by the mechanism of free radical peroxidation have emerged. This classification of antioxidants is based on the metabolic link to which the action of the antioxidant itself is directed. Therefore, the study of the effect of vitamin and mineral supplements on the indicators of antioxidant protection in farm animals is becoming increasingly important. The aim of this work was to study the effect of different doses of the vitamin-mineral supplement "Tekro" on the biochemical parameters of the New Zealand White breed rabbits. Scientific and economic experience on the topic of work and production verification were carried out on clinically healthy New Zealand White rabbits. The animals were fed with complete feed. Access to food and water was free. To conduct research on the farm, 4 groups of animals were formed: 1 control group, whose animals consumed the basic diet (RR); 2 research – OR with the content of vitamin and mineral supplements (VMS) "Tekro" 3.0%; 3 research – OR with the content of VMS "Tekro" 3.5%; 4 research – OR with a content of VMS "Tekro" 4.0%. The activity of antioxidant enzymes and the content of ceruloplasmin in the blood plasma and liver of rabbits were determined on the 45-th, 60-th, 75-th and 90-th days. In the blood plasma of rabbits from the control and experimental groups, a change in the activity of antioxidant defense enzymes was established. The obtained research results showed that long-term use of the vitamin-mineral supplement "Tekro" significantly positively influenced the antioxidant defense system of the animal body. The established changes in the indicators of antioxidant protection indicate the tension of balancing the prooxidant-antioxidant system of young rabbits. In particular, this phenomenon can be explained by the age-related characteristics of the formation of the antioxidant system of the growing organism of the New Zealand white breed rabbits under the influence of the vitamin-mineral supplement "Tekro". This phenomenon may be evidence of the stabilization of antioxidant processes in the blood plasma of rabbits of the experimental groups as a result of the complex effect of the optimal dose of biologically active substances of the vitamin and mineral supplement. Prospects for further research consist in a detailed study of the effect of various doses of the vitamin-mineral supplement "Tekro" on protein metabolism in the rabbit's body.
Interspecific hybrids of Juglans regia L.
Authors:   National University of Life and Environmental Sciences of Ukraine, Mezhenskyj V.
Published: March 2021

Persian walnut (Juglans regia L.) is an important tree primarily for its nutritious nuts and high-quality wood. Based on the analysis of literature sources, it was found that hybridization played a significant role in the evolution of the genus Juglans. Persian walnut can interbreed with many walnut species with the formation of fertile hybrids. There are two-species, three-species, and four-species hybrids in different combinations of crossings. They are used in forestry as a source of wood, in horticulture as rootstocks, and in breeding for more durable resistance against pathogens and tolerance against abiotic stresses. Some interspecific hybrids have validly published scientific names, but many of the proposed names do not meet the rules of the International Nomenclature Code for algae, fungi, and plants.
Late Retrieval of the Leadless Micra Transcatheter Pacemaker System
Authors: Minami Kentaro
Published: March 2021

Aim: We report our single-center experience with the retrieval and replacement of the chronically implanted Micra transcatheter pacing system (TPS). Material and Methods: We included 6 patients with an implanted the Micra TPSs who subsequently underwent transvenous method of retrieval at our institution. The indication for device retrieval was pacemaker syndrome in two patients, battery depletion in three patients, and need for upgrade to biventricular pacing in one patient. Results: After an implantation duration of 555 ± 373 days, the overall retrieval success rate was 83.3%, 5 of 6 patients. No procedure-related adverse device events occurred. In the single patient with unsuccessful retrieval, intracardiac echocardiography revealed that the Micra TPS was embedded within the cardiac wall and surrounding tissue. After retrieval, four patients received a new Micra TPS. Conclusions: Late retrieval of an implanted Micra TPS was safe and feasible, which indicates the possibility for their safe and elective replacement with a new leadless pacing device.
New data on diagnostics and distribution of the little-known comb-clawed beetle Cornucistela serrata (Coleoptera: Tenebrionidae: Alleculinae)
Authors: Nabozhenko M.V. , Matsumoto K.
Published: March 2021

Additional diagnostic characters of the little-known alleculine species Cornucistela serrata Campbell, 1980 are discussed. Variability of ocular index, a character widely used in the systematics of Alleculinae, is demonstrated. The distribution of C. serrata is amended; the species is known from the central part of Saudi Arabia and not from western provinces of the country as previously thought. A corrected key to species of Cornucistela Campbell, 1980 is given.
EORETICAL AND PEDAGOGICAL FOUNDATIONS OF PREPARATION OF THE FUTURE TEACHER OF PHYSICAL CULTURE
Authors: Imangalikova I. , Imangalikova A. , Abekov N. , Аbekov R.
Published: March 2021

Проанализирована проблема гиподинамии, способы решения данной проблемы и системы повышения качества программы физкультурной дисциплины с целью улучшить качество жизни и здоровья среди населения.
РЕАЛИЗАЦИЯ ПРИНЦИПОВ СИСТЕМНОГО ПОДХОДА В УПРАВЛЕНИИ ИМИДЖЕМ ГОСУДАРСТВЕННЫХ ГРАЖДАНСКИХ СЛУЖАЩИХ
Authors: Dambueva V.
Published: March 2021

В статье представлены компоненты системы управления имиджем государственных гражданских служащих, а также модель анализа имиджа государственных служащих. Автор предлагает использовать конкретный алгоритм управления имиджем государственных гражданских служащих, процедуры которого разработаны в рамках системного подхода.
ИСПОЛЬЗОВАНИЕ ЭЛЕМЕНТОВ STEAM-ОБРАЗОВАНИЯ В МЕЖПРЕДМЕТНОЙ ИНТЕГРАЦИИ БИОЛОГИЧЕСКИХ ЗНАНИЙ ШКОЛЬНИКОВ НА БАЗЕ СОЗДАВАЕМОЙ В РОССИИ СЕТИ КВАНТОРИУМОВ
Authors: Хачатурьянц В. , Теремов А.
Published: March 2021

В современном обществе интеграция является одним из основных подходов к процессу обучения школьников. Интегрированный подход способствует развитию творческих и познавательных способностей учащихся. Продуктивным технологическим решением создания межпредметных связей является STEAM- образование, которое основано в объединении основных направлений обучения. Кванториумы, создаваемые в России, позволяют применять STEAM – технологии для реализации интегрированного подхода. В статье приведены примеры заданий, включающие элементы STEAM - обучения, которые можно применять на уроках биологии.
CO-CYCLIZATION OF ETNCO AND ME2CO AS THE RESULTS OF THEIR SELECTIVE INSERTION INTO THE NIOBIUM-CHLORINE BOND
Authors: Ovchinnikova N. , Eremenko I.
Published: March 2021

Development of the new methods for drug production is impossible without reliance on the novel and unorthodox approaches to the synthesis of heterocyclic complexes and compounds.The method is based on the study of new aspects of the of two types of behavior of the coordinated molecules in reaction - their ability to insert into the same transition metal-halogen bond, and their ability to form the unusual heterocyclic ligands, or even molecules after leaving the complex’s coordination sphere. This will make it possible not only to synthesize the already-known compounds under milder conditions, but to also obtain new ones as products of such mixed condensation reactions. On the one hand, this opens up new possibilities for designing and performing the intraspherical "stitching" of ligands and their synthesis with high efficiency and selectivity. 

On the other hand, these reactions can be considered a significant contribution to the fundamental coordination chemistry in terms of illustration of the new modalities of the mutual influence of ligands, namely their ability to stimulate each other for a mutual insertion, and sheds light on the mechanisms of the intraspheric condensation. Oxadiazine derivatives, just like the derivatives of triazine we synthesized and reported previously, could become a foundation for the generation of biologically-active compounds, often containing heterocyclic fragments and frequently used for the treatment of malignant tumors. It can be expected that the developed method will find use in the synthesis of the new classes of potential antitumor compounds.

We have previously found that organic isocyanate not only themselves insert into M-Hal bond, but can also activate the insertion of acetonitrile, the resulting heteromolecular chain of inserted molecules being composed of two MeNCO and one MeCN fragments. Such a structure of this complexes was confirmed be synthesis of striazine derivatives on their base. In this work was to determine optimum condition for the insertion of ethyl isocyanate with acetone into niobium-chlorine bond, as well as their subsequent mixed co-cyclization with obtaining of oxadiazine derivative.
FORMATION OF ECOLOGICAL CONSCIOUSNESS
Authors: Корнеева Л. , Мясникова Н. , Грошева С. , Стасенко Н.
Published: March 2021

The state of the environment largely depends on the competence and level of environmental training of technical specialists. The purpose of education is: "From education about the environment to education for the environment". The concept of environmental education is the basic idea underlying the formation of a system of views in the learning process. The formation of ecological consciousness of pupils and students from primary classes to the graduation of qualified specialists with a broad environmental education - nature users of a new generation were investigated.
MONITORING OF ENVIRONMENTAL OBJECTS USING ECOLOGICALLY CLEAN ELECTRODES
Authors: Аронбаев Д. , Аронбаев С. , Исакова Д.
Published: March 2021

The review article presents the achievements of stripping voltammetry with modified environmentally friendly carbon-containing electrodes in environmental monitoring of the environment. The main objective of the research was the complete elimination of toxic mercury from the analytical procedure and its replacement with modifiers, which include bismuth, hydroxyapatite, montmorillonite, ionic liquids, chitosan, materials based on plant and animal cells, as well as their composites with graphite. The issues of development creating microchips with the use of screen printing technologies for solving problems of microtechnology and innovative technologies in the manufacture of microelectrodes that allow analysis in microvolumes of samples are considered. Examples of the use of bismuth and hydroxyapatite modified screen-printed electrodes in the analysis of heavy toxic metals in environmental objects are given. Screen-printed electrodes allow the use of portable systems for real-time analysis, and the automation of their production process makes them more versatile for routine use at low costs, which, in turn, allows their disposal use, especially in demand for non-invasive medical diagnostics.
SOME RISK FACTORS OF CARDIOVASCULAR DISEASES IN THE PERM REGION
Authors: Корягина Н. , Мелехова О. , Мальцев А. , Прохоров К. , Корягин В.
Published: March 2021

Risk factors for cardiovascular diseases (CVD) were studied in residents of the Perm region of working age (18-45 years). The prevalence of hypertension was within 19%. The level of blood pressure was: systolic - 119.3 mm Hg. ± 0.78 mm Hg, diastolic - 88 mm Hg ± 0.47 mm Hg Signs of hypothyroidism were found in 8.0% of women and 15.6% of men.
PRECEDENT NAMES IN URBAN ERGONYMY (ON THE MATERIAL OF ERGONIMS G. GYANJA)
Authors: Tagieva K.
Published: March 2021

In the article, we consider the ergonyms of the city of Ganja as a precedent name. It analyzes the development of precedent ergonomics and their role as a carrier of cultural information. The article emphasizes that ergonyms have become part of the culture of the people in the modern world, an indicator of the functional capabilities of their language and are due to the national and cultural traditions of the people.

The main aim of the study is to characterize the potential for using precedent ergonomics. The object of the research is the national and cultural peculiarities of precedent ergonyms, the subject is the peculiarities of their use. The study used methods of descriptive, observational and semantic analysis. The research reveals the specific features of the use of precedent names in ergonomics; discover that precedent ergonyms make it possible to convey information in a vivid, concise and accessible form.
WIND POWER PLANT PARAMETERS OPTIMIZATION MODEL
Authors: Sidorenko G. , AlJamil A.
Published: March 2021

A technical and economic model of a wind power plant has been developed. Parameterization was carried out and the main parameters of the wind power plant were identified. Statistical relationships of parameters with capital investments in wind turbines and costs of their operation and maintenance were established. The criterion for the search for optimal parameters is taken as the minimum discounted unit costs for the production of electrical energy for the economic life of the wind power plant. To do this, the electricity production in a wind power plant must be maximized by reducing the so-called wake effect that is created in a wind farm due to the shading of some wind turbines by others. The velocity reduction behind each wind turbine is estimated. An algorithm for optimizing the parameters of a wind power plant has been developed. An optimization model was used to determine the parameters of the Hasia wind power plant.
PRINCIPLES AND FEATURES OF RESIDENTIAL LANDSCAPING DEVICES
Authors: Sidorova A. , Yarullina D. , Abduhanova N.
Published: March 2021

This article discusses the landscaping of the residential area as a whole and the arrangement of landscaping of individual zones of the residential complex. The features of the arrangement of landscaping, individual parts of the complex are also considered.
Piotr Potiomkin’s “Green Hat” and Russian Émigré children’s literature
Authors:   he “Aquilon” Books & Publishing, Ustinov Andrei
Published: March 2021

The essay reconstructs history of the 1924 publication of Piotr Potiomkin’s (1886—1926) poem for children Green Hat in a wider context of the Russian émigré literary culture. A well-known writer before the revolution, the author of two books of poetry Funny Love and Geranium, Potiomkin found himself after emigrating to Chishinau and further to Prague, on the periphery of the Russian Diaspora. In 1922 he slowly started to publish his works in the periodicals of “Russian Berlin.” Sasha Chiornyi, his friend from the era of the Satyricon magazine, included two of Potiomkin’s poems in the Rainbow, the first children’s anthology which Chiornyi edited for the Slovo publishing house. By that time Chiornyi occupied a leading position in the émigré children’s literature. He began to invite Potiomkin’s partici- pation in the publishing enterprises of “Russian Berlin,” and recommended the poet to the Volga publishing house as a potentially valuable author. Potiomkin was one of the creators of the genre of “a poem for children” in pre-revolutionary children’s literature—-in 1912 the magazine Galchionok published his “story in verse” Boba Skvozniakov in the Country. Therefore, Potiomkin offered the Volga to publish another “poem for children” Green Hat. As a book designer he invited Hans Fronius (1903—1988) who at the time was a student at the Kunstakademie in Vienna. Later Fronius became the first illustrator of the literary works of Franz Kafka.
Double Concert in F Major by Antonio Soler
Authors: IBANESCU Daniela-Corina
Published: March 2021

: In his vast creation, Soler mirrors a complex and visionary thinking. The work we are analyzing is the 4th Solerian concert, which imagines a majestic picture. It is one of the six concerts for two bound organs destined for the infant of Spain, their festive character not being accidental. From the very beginning, Soler guides in finding the right tempo to create the royal atmosphere. It should be noted that this concert is the only one of the six with an anacrusis profile. In part 2, Soler greets us with Minué, the refinement and gallant style of the beloved dance developing during 4 variations. As a whole, this concert is a real jewel of instrumental complexity in a balanced construction of expressive richness. Noble, singable and virtuoso, Soler's complex language capitalizes on the three facets of the artist who brings them on stage: the expressive performer, the virtuoso instrumentalist and the inquisitive musician.
Repetitive Minimalism in the Work of Philip Glass. Composition Techniques
Authors: ISAC Iuliana
Published: March 2021

The music which renders Philip Glass’ vision is based on repetition. Musical figures are structured according to the so-called additive method – undoubtedly the main technique determining the characteristics of his style. It consists of adding new elements to the basic melodic and/or rhythmic structure, resulting in an expanding musical discourse which is augmented or diminished and is applied more and more melodic and rhythmic constraints, depending on the intentions of the compositional project. There is also the loop technique, which becomes manifest by a series of added elements from electro acoustics and which is almost omnipresent as a basic minimalist technique.
The directorial conception on operetta Silvia by Emmerich Kálmán
Authors: BOURCEANU Mădălina
Published: March 2021

With a well-developed dramaturgy, "Silvia" surprises by the way in which the meticulous musical characterizations of the characters were made, offering the protagonists distinct personalities. The most popular moments that place the opera in the first line of success of Emmerich Kálmán's works, reflect very engaging rhythms. The directorial conception pleads precisely for this “essence” of operetta, of the genre show, alert, frothy, built of overturns, glasses of champagne and fine humor. The director's conception must include the appreciation of style and the visual side. The directorial conception and the artistic manifestation must achieve an aesthetic fulfilment and be legitimized in the staging of the show by the rightness of the concrete quality of the actors / images relationship
From Pure Source Only – Collection of Hungarian Folk Songs Project
Authors: SZALAY Zoltan
Published: March 2021

The collection contains a selection of folk songs from the Hungarian population living in Romania. Of the four volumes planned, three have been published so far. The entire collection is expected to span 18 regions and 3 micro-regions, as well as a strip of hundreds of kilometers from Transylvania and other areas outside Transylvania. These include some more developed areas which abandoned their traditions in the first half of the last century, and some more traditional regions. The first three volumes comprise folk songs from 174 localities, collected by 126 collectors, including Béla Bartók, Zoltán Kodály, László Lajtha, János Jagamas and Zoltán Kallós. The collections took place between 1899 and 2017. The melodies have been selected from the archives of Transylvanian and Hungarian institutions, as well as from audio materials accompanying various publications. In this selection I have tried to add as many songs as possible which belong to the old strata of folk songs. I have tried to include as many pentatonic melodies as possible because these strata predominantly feature this scale. Also, in the last century the everyday folk-song repertoire shifted toward a fixed-rhythm performance mode. An ancient form, with its speech-like mode of performance, is now in the process of being lost. Therefore, the number in the published volumes is smaller than that of the folk songs performed in a tight rhythm.
Drama-Music Communication in Opera Performance
Authors: TĂBĂCARU Roxandra
Published: March 2021

The study “Drama-Music Communication in Opera Performance” builds on my 35-year experience of lyric drama in opera production. In my career as a director, which spanned from Baroque opera to contemporary opera, I was intrigued by the multiple connections between the musical dramaturgy, vocal expressiveness, stage image and impact on the audience. Consequently, I realised that all these elements which rely on musical scores are connected by something similar to the principle of communicating vessels: with genuine and intense musical-dramatic communication, the artistic emotion may reach the same level in all the components of the connections mentioned above.
Vocal technique in the formation stages of the lyric artist
Authors: GIOL-CALEFARIU Emilia
Published: March 2021

Singing is the way of expression through which feelings, experiences, an ideational content are poetically expressed; in its absence the vocal qualities cannot justify the purpose of the interpretation. The topicality of music education for young performers is determined by an appropriate approach to the process of knowing the essential structure of singing, by understanding and mastering the multiple styles and ways of interpreting each genre, all in conjunction with an integration of historical views on the art of singing. Finding directions of orientation and thinking in the field of vocal interpretation, corroborated with the identification of some intrinsic values of it will contribute to achieving a stable foundation on which the lyrical artist can build a career in interpretation.
Brüchige Allianzen. LSBTIQ Aktivismen im Kontext der intersektionalen und dekolonialen Praxis der südafrikanischen Studierendenbewegung
Authors: Daniel Antje
Published: March 2021

Am 9.3.2015 bewarf Chumani Maxwele die Statue von Cecil Rhodes am Universitätsgelände der University of Cape Town mit Fäkalien. Aus dem Unmut gegen die Präsenz des Kolonialisten Rhodes an der Universität und damit aus der Kritik an dieser diskriminierenden Erinnerungskultur entwickelte sich eine der größten sozialen Bewegungen Südafrikas seit der Überwindung der Apartheid. Die Studierenden forderten mit dem Rhodes Must Fall und später mit Fees Must Fall den freien Zugang zur tertiären Bildung und einen universitären Raum jenseits von Diskriminierung und Rassismus. Dekolonisierung und Intersektionalität waren dabei zwei zentrale Schlagworte für das Verständnis der Unrechtserfahrungen der Studierenden und zugleich fassten sie die multiplen Forderungen der Studierenden zusammen. Die vielfache Zuschreibung dessen was Dekolonisierung und Intersektionalität bedeuten, ermöglichte es, Allianzen zwischen unterschiedlichsten Studierenden zu bilden und auch jene Studierenden, wie die LSBTIQs zu integrieren, welche aufgrund ihrer mehrfachen Diskriminierung häufig ausgeschlossen bleiben. Im Protestverlauf erlebten jedoch LSBTIQs Studierende vermehrt Diskriminierung und Ausschluss. Geschlechterpositionen wurden zum Streitpunkt und stellten die Allianzen infrage. Was mit einer geteilten Forderung von Dekolonisierung und Intersektionalität begann und damit mit dem Streben nach einem herrschaftsfreien Raum, der Diskriminierung und Rassismus überwindet, endete in der Reproduktion von Ungleichheit und der Herausbildung von Machtpositionen. Allianzen brachen auf, trugen zur Zersplitterung der Studierendenbewegung bei und ließen Gegenproteste entstehen, welche die herrschaftskritischen Proteste in ihrer Reproduktion von Ungleichheit hinterfragten. Vor dem Hintergrund der Studierendenbewegung wird die Brüchigkeit von Allianzen deutlich ebenso wie Notwendigkeit, analytisch den Protestverlauf zu analysieren, denn erst dieser zeigt das Entstehen von Allianzen einerseits sowie von Macht- und Exklusionsdynamiken andererseits.
Für „ein unabhängiges visuelles Denken“. Zur Kunst- und Kultursoziologie des peruanisch-mexikanischen Theoretikers Juan Acha
Authors: Kastner Jens
Published: March 2021

Wie die Kunstproduktion mit der sie umgebenden Kultur verknüpft ist und wie sich beide gegenseitig beeinflussen, ist eine zentrale Fragestellung für die – nicht nur soziologisch motivierte – Kunst- und Kulturtheorie. Die Antworten des in Peru geborenen Kunstkritikers und Kulturtheoretikers Juan Acha (1916-1995) auf diese Frage machen sein Werk zu einem außerordentlichen Beitrag zu der disziplinübergreifenden Debatte um Kunstproduktion und Kultur, der im deutschsprachigen Raum bisher nicht wahrgenommen wurde. Denn Acha gibt diese Antworten vor dem Hintergrund einer präzisen Kenntnis globaler kunsttheoretischer Debatten einerseits und einer besonderen Berücksichtigung der lateinamerikanischen Situation andererseits, in der die kolonialen Grundlagen von Ökonomie und Kultur besonders betont werden. Die zentralen Thesen Achas einem deutschsprachigen Publikum zugänglich zu machen, ist das primäre Ziel dieses Textes. Der Aufsatz beansprucht darüber hinaus, über die Diskussion des Spannungsverhältnisses, das sich im Werke Acha auftut, die Relevanz seines Werkes für heutige Debatten aufzuzeigen: Es handelt sich um die Spannung zwischen einer empirisch-theoretischen Einsicht in die reproduktive Funktion von Kunst auf der einen Seite und die emanzipatorischen Hoffnungen, die auf künstlerische Praktiken zugleich und trotzdem gesetzt werden andererseits. Der Text geht in fünf Schritten vor: Erstens wird das grundlegende Plädoyer Achas für eine Soziologie der Kunst und der dabei zentrale Begriff des no-objetualismo vorgestellt. Zweitens wird die Besonderheit von Achas Ansatz gegenüber anderen, vergleichbaren theoretischen Herangehensweisen an die Kunst herausgestrichen, die in der Bedeutung liegt, die Acha dem Kolonialismus einräumt. Mit dessen analytischer Bedeutung geht die normative Hinwendung zu einer Redefinition der Kunst einher. Drittens wird Achas Fokus auf den ästhetischen Konsum nachgezeichnet und seine relationale Methode skizziert, um dann viertens näher auf das politische Engagement einzugehen. Fünftens wird der Einfluss von Achas Werkes auf andere TheoretikerInnen und auf die künstlerischen Bewegungen seiner Zeit skizziert.
Comparing the original and biosimilar biotherapeutics of the monoclonal antibody eculizumab by intact mass measurement and middle-up mass spectrometry analysis
Authors: Degterev M. B. , Shukurov R. R.
Published: March 2021

Objectives. In this biosimilar research, we compare the monoclonal antibody eculizumab obtained from different drugs [original Soliris® (Alexion Pharmaceuticals) and candidate Elizaria® (Generium)] by intact mass measurement and middle-up mass spectrometry analysis to enhance the role of mass spectrometry methods in biopharmaceutical development processes.

Methods. The intact mass measurement is performed using a high-resolution ESI-MS. The middle-up analysis is performed by reversed-phase high-performance liquid chromatography with ESI-MS detection, subsequent IdeS treatment of antibodies, and disulfide bond reduction.

Results. We have shown some small differences between the original and candidate drugs in the minor glycans level. Man5 glycan is only found in the original Soliris, and G0 is only found in the Elizaria. Glycation sites are also found in the light chain and Fd subunits of the original Soliris. The glycation level does not exceed 4.4%. The non-clipped C-end lysine level and G0F glycan levels are slightly lower in the original Soliris. All registered differences are not crucial for eculizumab’s quality and do not affect its effectiveness and preclinical safety. Generally, the results show a high level of similarity between the original and candidate drugs.

Conclusions. The comparative mass spectrometry analysis of eculizumab in the original Soliris and Elizaria allows us to estimate their high degree of similarity by molecular masses and major modification profiles.
Method for extracting square and cube roots in the binary number system
Authors: Zlatopolski D. M.
Published: March 2021

The article describes in detail the methods of extracting square and cube roots in the binary number system. The method for extracting the square root of a binary number is similar to the corresponding method for decimal numbers, which is called the "column method". As for decimal numbers, when choosing the next digit of the root, twice the current value of the root, represented in the binary system, is used. When extracting the cube root (also "column"), there are two differences from the decimal system. The first is that instead of 300 (the product of 3 and 100), the binary number 1100 is used (that is, the product of the binary equivalents of the numbers 3 and 4). The second difference is that instead of the number 30 (the product of 3 and 10), the binary number 110 is used (that is, the product of binary analogs numbers 3 and 2). To facilitate the selection of the next root digit (0 or 1), a number of standard values have been calculated, depending on the current root value. Assignments for independent work of students are offered.