bluuebunny/crossref_metadata_2025 huggingface dataset:
KEWENANGAN PENYADAPAN DALAM PEMBERANTASAN TINDAK PIDANA KORUPSI
Authors: Saragih Yasmirah Mandasari , Sahlepi Muhammad Arif
Published: December 2022

Aturan hukum mengenai penyadapan tersebut masih tersebar di dibeberapa Undang-Undang. Hal tersebut dikarenakan tidak ada aturan hukum yang secara khusus mengatur mengenai penyadapan. Dikhawatirkan terjadi ketidakpastian hukum yang memiliki kewenangan melakukan penyadapan dan mengenai pengakuan hasil penyadapan sebagai alat bukti. Terlihat adanya pertentangan antara dua kepentingan negara dalam melindungi hak privasi warga negaranya dan kepentingan negara dalam menegakkan hukum. Berdasarkan pertentangan antara dua kepentingan tersebut menyebabkan ada sebagian warga negara yang merasa haknya konstutisionalnya dilanggar dengan adanya tindakan penyadapan. Masyarakat mengajukan Judicial Review atau pengujian kembali terhadap beberapa aturan yang mengatur mengenai penyadapan di Mahkamah Konstitusi. Putusan mahkamah konstitusi tersebut adalah Putusan Mahkamah Konstitusi Nomor 006/PUU-I/2003, Putusan Mahkamah Konstitusi Nomor 012-016-019/PUU- IV/2006, Putusan Mahkamah Konstitusi Nomor 5/PUU-VIII/2010 dan Putusan Mahkamah Konstitusi Nomor 20/PUU-XIV/2016. Penelitian ini bertujuan untuk menganalisis Racio Decidendi Putusan Mahkamah Konstitusi Nomor 5/PUU- VIII/2010 dan Putusan Mahkamah Konstitusi Nomor 20/PUU-XIV/2016 dan menganalisis kewenangan lembaga pemenegak hukum dalam perolehan alat bukti hasil penyadapan pasca Putusan Mahkamah Konstitusi. Permasalahan dalam penelitian ini adalah Bagaimana Konsep Pengaturan Hukum Penyadapan berbasis Perlindungan Terhadap Hak Privasi Seseorang, kemudian Bagaimana Manfaat terhadap adanya pengaturan Hukum Penyadapan atas pelaku tindak pidana korupsi di Indonesia. Sedangkan penelitian ini adalah dapat dikategorikan menjadi penelitian doktrinal atau disebut juga penelitian hukum normatif. Penelitian doktrinal adalah suatu penelitian hukum yang bersifat peskriptif bukan deskriptif sebagaimana ilmu sosial dan ilmu alam. Pendekatan- pendekatan yang digunakan adalah pendekatan undang-undang (statute approach), pendekatan kasus (statute approach), pendekatan historis (historical approach), pendekatan komparatif (comparative approach), dan pendekatan konseptual (conseptual approach).Kata Kunci : Penyadapan, Tindak pidana korupsi, Kewenangan.
PERAN APARAT PENGAWAS INTERN PEMERINTAH (APIP) UNTUK MEWUJUDKAN GOOD GOVERNANCE DALAM PENCEGAHAN TINDAK PIDANA KORUPSI DI BIDANG PENYEDIAAN BARANG DAN JASA
Authors: Alfianto Dwi
Published: December 2022

Dalam Penyediaan barang dan jasa khususnya pada sektor publik atau pemerintah, adanya tata pemerintahan yang baik dan bersih merupakan suatu keharusan. Untuk melaksanakan tata pemerintahan yang baik atau good governance Pemerintah menerapkan prinsip akuntabilitas dan memberdayakan sumber daya dibidang pengadaan barang dan jasa beserta aparatur yang melakukan audit atau pengawasan. Kinerja organisasi pemerintah khususnya dalam pengadaan barang atau jasa pada sektor publik atau pemerintah sudah saatnya lebih mendapatkan prioritas untuk diperhatikan yang salah satunya melalui kewenangan dan kegiatan pengawasan yang tepat tujuan dan sasaran dari Aparat Pengawas Intern Pemerintah (APIP).Kegiatan pengadaan barang/jasa pemerintah kerap kali dijadikan momentum untuk mendapatkan keuntungan dengan menyalahgunakan wewenang yang berujung pada korupsi.Dalam penerapan good governance pada pengadaan barang/jasa pemerintah maka yang perlu ditelusuri adalah bagaimana aspek hukum pengadaan barang dan jasa yang menimbulkan kerugian negara dan bagaimana peran dan wewenang APIP dalam pencegahan tindak pidana korupsi di bidang penyediaan barang dan jasa. Pada akhirnya melalui kewenangan APIP diharapkan harus lebih berperan didalam pencegahan tindak pidana korupsi pada pengadaan barang dan jasa pemerintah.Kata kunci : Penyediaan barang dan jasa, Korupsi, Good Governance
TUGAS POKOK PEJABAT PEMBUAT AKTA TANAH DALAM KEGIATAN PENDAFTARAN TANAH
Authors: Probondaru Ignatius Pradipa
Published: December 2022

ABSTRAK Jaminan kepastian hukum di bidang pertanahan memerlukan peraturan tertulis dan dilaksanakannya kegiatan pendaftaran tanah. Pemerintah diwajibkan menyelenggarakan kegiatan pendaftaran tanah, baik berupa kegiatan pendaftaran tanah untuk pertama kali, maupun kegiatan pendaftaran tanah untuk pemeliharaan data. Untuk kegiatan pendaftaran tanah bagi pemeliharaan data, jabatan Pejabat Pembuat Akta Tanah diperlukan. Permasalahan yang dibahas adalah bagaimana tugas pokok utamanya PPAT dalam kegiatan pendaftaran tanah.  Metode penelitian yang digunakan adalah penelitian hukum normatif dengan menggunakan data sekunder yang dianalisis secara kualitatif. Hasil penelitian menunjukkan bahwa tugas pokok Pejabat Pembuat Akta Tanah adalah menjalankan sebagian kegiatan pendaftaran tanah dengan membuat akta sebagai bukti telah dilakukannya perbuatan hukum tertentu mengenai hak atas tanah atau hak milik atas satuan rumah susun (HMSRS) yang akan dijadikan dasar bagi pendaftaran perubahan data pendaftaran tanah. Untuk meningkatkan pelayanan PPAT kepada masyarakat, diterbitkan PP 24 Tahun 2016 yang memperluas daerah kerja PPAT sampai tingkat provinsi. Untuk meningkatan kualitas pelayanan kepada masyarakat, Kementerian Agraria dan Tata Ruang/Badan Pertanahan Nasional melakukan pembinaan dan pengawasan PPAT melalui kode etik PPAT.Kata kunci: Pendaftaran Tanah dan Pejabat Pembuat Akta Tanah
PERLINDUNGAN TERHADAP ANAK SEBAGAI KORBAN TINDAK PIDANA PEDOFILIA
Authors: Multiwijaya Vientje Ratna
Published: December 2022

ABSTRAKPengabdian kepada masyarakat mengenai perlindungan terhadap anak korban tindak pidana pedofilia  menitikberatkan kepada perlindungan hukum bagi korban pedophilia dari sudut  hukum  perlindungan anak. Khususnya pengabdian masyarakat ini memberikan pemahaman macam-macan kekerasan seksual/pedofilia yang dapat memberikan dampak anak menjadi malu, rendah diri, mengalami luka fisik, kerusakan alat reproduksi  bahkan akibat tersebut bisa  membekas hingga anak dewasa dan juga memberikan pengetahuan tentang adanya sanksi pidana terhadap pelaku pedopilia. Pengabdian masyarakat di RPTRA Kedoya Utara, Kecamatan Kebun Jeruk Jakarta Barat pada Senin, 12 November 2018 dalam bentuk penyuluhan dan posbakum dilakukan dengan cara memberikan ceramah, disertai contoh-contoh kasus yang aktual dan sering terjadi dalam masyarakat. Kepada peserta penyuluhan diberi kesempatan untuk melakukan tanya jawab yang berkaitan dengan hukum perlindungan anak atau hal lain yang berhubungan dengan hukum. Dengan demikian tujuan pengabdian masyarakat  dapat tercapai yaitu masyarakat memahami serta memiliki pengetahuan tentang perlindungan anak, masalah pedophilia,  muatan yang dilarang dan sanksi pidana pelaku pedopilia. Kata kunci: Anak, Korban Tindak Pidana Pedopilia dan Hukum Perlindungan Anak
PENYALAHGUNAAN NARKOTIKA, DIPENJARA ATAU DIREHAB
Authors: Iskandar Anang
Published: December 2022

Narkotika adalah obat atau bahan yang bermanfaat di bidang pengobatan, kesehatan, dan ilmu pengetahuan. Penggunaannya diwajibkan sesuai standart yaitu atas petunjuk dokter. Penyalahgunaan diluar petunjuk dokter dilarang karena dapat menyebabkan sakit ketergantungan narkotika. Penyalahguna narkotika diancam dengan pidana namun dijamin mendapat rehabilitasi oleh Undang-Undang No. 35 tahun 2009 tentang Narkotika Pasal 4 huruf (b dan d). Implementasi penegakan hukumnya penyalahguna dijatuhkan hukum penjara. Obyek Penelitian  “Apakah Putusan Hakim yang menjatuhkan hukuman penjara bertentangan dengan UU no 35/2009 tentang narkotika ?” dan “Apakah alasan hakim tidak menjatuhkan sanksi rehabilitasi?”, Metode penelitian  menggunakan normatif dan sifat penelitian deskriptif dengan menggunakan data primer dan sekunder dan dianalisis secara kualitatif. Penarikan kesimpulan dengan cara deduktif. Putusan hakim menjatuhkan sanksi pidana bertentangan dengan UU No. 35 tahun 2009, namun diatur secara khusus dalam UU no 35 tahun 2009 tentang narkotika, bahwa penyalahguna narkotika dijamin mendapatkan upaya rehabilitasi dan  hakim dalam memeriksa perkara penyalahgunaan narkotika wajib memperhatikan (pasal 127 ayat 2) penggunaan  kewenangan absolut untuk memutuskan yang bersangkutan menjalani rehabilitasi bila terbukti bersalah dan menetapkan yang bersangkutan untuk menjalani rehabilitasi bila tidak terbukti bersalah (pasal 103) dengan lebih dulu melakukan kewajiban memeriksa apakah penyalahguna tergolong sebagai korban penyalahgunaan narkotika atau pecandu (pasal 54) dan apakah penyalahguna atau orang tuanya sudah melaporkan ke rumah sakit yang ditunjuk untuk mendapatkan perawatan/rehabilitasi (pasal 55). Sedangkan alasan mengapa tidak menjatuhkan sanksi rehabilitasi karena adanya beda persepsi pada penegak hukum.Kata Kunci: Tindak pidana narkotika, sanksi rehabilitasi
PERLINDUNGAN TERHADAP PEREMPUAN DARI TINDAK PIDANA PERKOSAAN BERDASARKAN HUKUM HUMANITER
Authors: Permanasari Arlina
Published: December 2022

Abstract Sexual violence including rape during armed conflict is a criminal offense that committed long ago even before World War I and still continues to occur in recent conflicts. The Geneva Conventions of 1949 and their Additional Protocols regulating the protection of victims of conflict in both international and non-international armed conflicts provide special protection to women by respecting the dignity, family dignity and rights of women in armed conflict. The only article that regulates rape, forced prostitution and other sexual violence is only found in Article 27 paragraph (2) of Geneva Convention IV in international armed conflict and Article 4 of Additional Protocol II 1977 (in non-international armed conflict)  which receives a lot of criticism because it does not fully regulate rape substantially, even it is not included as a grave breah of the Geneva Convention. State practice through the international tribunals namely ICTR and ICTY in the Akayesu, Furundžija and Kunarac cases which was finally integrated in the Elements of Crimes of ICC Statute establishes legal protection for women from sexual violence including rape during wartime, which is relatively more normatively acceptable at both the international and national levels.   Keywords: rape, forced prostitution, indecent assault, ICC Statute elements of crimes, humanitarian law.
الجموع في الآيات القرآنية المتعلقة بالرسول محمد(^)دراسةُ صرفية دلالية
Authors: Ahmed Al-Khazraji Emad Hamid , Hajim Esraa Refaat
Published: December 2022

يتعامل البحث مع النقطة اللغوية ، وهي من الظواهر المتواطئة في اللغة العربية ، فهي فقيرة ، وهذه الدراسة تتماشى مع الدراسة الحدودية في القرآن ، وآيات النبي محمد (صلى الله عليه وسلم) كذكر الذكر ، والفتن الصغير ، والجنس ... باستثناء
الكثير من التفسيرات تتعامل مع هذه الدلالات التي تمت دراستها وصعبها وهذا يعني أن الأدينوم والاستحسان أفضل في النطق لاستخدامه على الرغم من علامات القرآن.
ينقسم البحث إلى العديد من الفينومينا ، pupolar detine
اللغة والفراغات طرق غير مبالية للشرانق وما قد يعنيه ذلك. بدءا ماي وماي بوبولور. يقدم هذا البحث موجزًا ​​عن طرق الحدقة الأخرى مثل الاسم والجنس وقطب البؤبؤ ويعطي النتائج كاملة.
التعلم والتعليم في الفكر التربوي الإسلامي
Authors: Al-Abd Muhammad Amin
Published: December 2022

قسم الباحث البحث إلى مقدمة وتمهيد واثني عشر مطلب وخاتمة.
ذكر في المقدمة إسهام علماء المسلمين في بيان جملة من هذه العوامل التي يمكن أن تؤثر في العملية التعليمية، واستقرأ الباحث هذه العوامل من مصادر الفكر التربوي الإسلامي، واستنبطها مسترشداً بالقواعد الأساسية في التدريس.
التمهيد:
المطلب الأول: التربية العقلية.
المطلب الثاني: التربية الجسمية.
المطلب الثالث: تحقيق الصحة النفسية (الانفعالية).
المطلب الرابع: إرشاد وتوجيه المتعلم.
المطلب الخامس: مدرسة المجتمع.
المطلب السادس: علاقة التعليم بسوق العمل.
المطلب السابع: مراعاة الفروق الفردية لدى المتعلمين.
المطلب الثامن: الوسائل التعليمية.
المطلب التاسع: إعداد المعلّمين وتدريبهم.
المطلب العاشر: التنظيم الإداري والشروط الوظيفيّة.
المطلب الحادي عشر: تعليم الإناث والذكور.
الخاتمة: ذكر فيها أهم التوصيات.
المباني الاثارية التي تعرضت للتدمير والتخريب على يد تنظيم داعش في محافظة صلاح الدين
Authors: Khalaf Ammar Sobhi , Mohammed Maher Hassan
Published: December 2022

يعتبر الجانب المعماري والفني ركيزة مهمة في الدراسات الأثرية ، ويساهم بشكل كبير وفعال في حقائق الدراسات الأثرية. تزداد الحاجة إلى التوثيق في الدراسات الأثرية عندما تكون هناك ظروف قد تؤثر على هوية هذه الآثار وتشير إلى أهميتها ومرجعيتها لدراسة كل ما يتعلق بها لأنها قد تتعرض للسقوط بسبب الظروف المناخية أو للتدمير والتخريب المتعمدين. كما في النماذج سوف ندرس. كان لا بد لنا من ذكر اهمية هذه المباني وتاريخها واهميتها في الحضارة العراقية وعناصرها المعمارية وتفصيل عناصر وبيان ملامح العمارة الرائعة التي دمرها تنظيم داهش والتي سنقوم بها. نتحدث عنها باختصار. ثم تحدث عن الأجزاء المدمرة وحجم الضرر مع الصور المصاحبة للمراحل قبل وبعد لإظهار الفروق في المبنى الواحد. تطلبت طبيعة البحث تقسيم المقدمة وكان القسمان والملحقات عبارة عن صور للبحث: ويتناول القسم الثاني دراسة موقع وتاريخ وتخطيط وزخارف مقبرة محمد الداري والجزء الثاني. الضرر الذي لحق به. وجاءت الخاتمة بأهم النتائج التي توصلت إليها الباحثة ثم الملحقات التي تضمنت صور المباني التي شملتها الدراسة.
Popularization of Scientific and Technical Knowledge, Aviation, Military and Political Issues Conceptualized in the Literary Works of Nikolai Nikolaevich Shpanov (1896-1961)
Authors: Bocharov Aleksei Alekseevich , Mikhailov Andrei Aleksandrovich , Fisheva Anastasiya Aleksandrovna
Published: December 2022

The paper discusses popular science and fiction (primarily science fiction) works of N.N. Shpanov, the Soviet writer and pilot, one of the founders of military fiction genre in Soviet literature. In his works a certain mood in society, its aspirations and expectations, supported by the country’s political leaders, are mirrored. The article analyzes as well N.N. Shpanov’s activity in the field of promotion of knowledge about aviation, writer's prediction on the course of the upcoming clash with a powerful western power (Germany), made by him on the eve of the Great Patriotic War, and the role of military aviation in this confrontation. The main conclusion of the study is that in the 1920-1930s N.N. Shpanov, having gained technical knowledge and broad experience in the period of his studying at the Polytechnic University, then at aeronautical courses and later on while serving in aviation, in his literary work popularizes new ideas coherent with geographical research, science, and technology, especially aviation. Since the late 1930s in writings of N.N. Shpanov the disposition towards spreading the ideas and policies of the Stalin period’s Soviet propaganda showed itself. The imprint of large-scale historical events, military, and technical concepts reflected in books of N.N. Shpanov makes the analysis of his works substantial as it is firmly bound with the history of science, aviation, and social consciousness in the USSR.
Outcomes in pituitary adenoma causing acromegaly following endoscopic endonasal transsphenoidal surgery
Authors: Chhabra Rajesh , Kumar Ashwani , Virk R. S. , Dutta Pinaki , Ahuja Chirag , Mohanty Manju , Dhandapani Sivashanmugam
Published: December 2022

Objectives:

The objectives of the study were to study the analysis of outcomes after endoscopic endonasal transsphenoidal surgery (EETSS) in acromegaly in terms of surgical complications, clinical improvement, endocrinological remission, achievement of prognostically critical growth hormone (GH) level, and requirement of additional treatment.

Materials and Methods:

The study included 28 acromegaly patients, who underwent EETSS. A 2010 consensus criterion was used for defining remission. Assessment of prognostically critical GH level (random value <2.5 ng/ml), the extent of resection and additional treatment, was done at post-operative week (POW) 12.

Results:

All adenomas were macroadenomas; with a mean volume of 16.34 cm3 (range, 0.4–99 cm3). Most adenomas had high-grade extensions. Most common suprasellar, infrasellar, anterior, and posterior extension grades were 3 (n = 13), 1 (n = 16), 1 (n = 14), and 0 (n = 20), respectively. Knosp Grade 3 was common on both sides (right, n = 9 and left, n = 8). One patient had already been operated on with EETSS, 1.5 years back from current surgery. Sixteen patients were on hormonal support, preoperatively. Four patients died during follow-up. Post-operative common complications were diabetes insipidus (DI, n = 18), cerebrospinal fluid rhinorrhea (n = 10), surgical site hematoma (n = 3), meningitis (n = 3), hydrocephalus (n = 2), and syndrome of inappropriate antidiuretic hormone (n = 1). The mean hospital stay was 11.62 days and 12.17 months were the mean follow-up period. At 12 POW, no improvement was seen in body enlargement and visual complaints, but all other complaints improved significantly except perspiration. Adenomas were decreased in all extensions except posterior and mean adenoma volume was reduced from 16.34 cm3 to 2.92 cm3 after surgery. Sub-total resection (STR, n = 10), near-total resection (NTR, n = 7), gross-total resection (GTR, n = 5), and partial resection (PR, n = 2) were achieved. Endocrinological remission and prognostically critical GH levels were attained in 29.17% (n = 7) and 66.67% (n = 16), respectively. NTR, GTR, STR, and PR were associated with 57.14%, 40%, 10%, and 0% endocrinological remission, respectively. Additional treatment was required in a total of 17 patients, three in GTR, nine in STR, three in NTR, and two in PR. Ten were treated with Gamma Knife radiosurgery along with medical treatment and seven with medical treatment alone.

Conclusion:

A successful EETSS can reduce adenoma volume to achieve clinical improvement, endocrinologic remission, and prognostically critical GH level with some complications related to surgery. Pre-operative larger volume and higher extension grades affect these outcomes adversely.
«BRIDGE» TO HEART TRANSPLANTATION: HEMOSORPTION, VENTRICULAR REMODELING OR LVAD? ABSTRACT
Authors: DENYSIUK K. , LOSKUTOV O , DRUZHYNA O
Published: December 2022

Background. Heart failure (HF) is a global public health problem worldwide [2]. The most frequent cause of severe HF is dilated cardiomyopathy (DCM) [6]. The morbidity and mortality rate are constantly growing, which indicates the presence of unresolved issues in the therapy of this nosology [3].
Aim. To determine the efficacy of alternative methods of treatment in patients with severe HF caused by DCM.
Materials and methods. A retrospective analysis of the treatment results in 86 patients with severe HF on the background of DCM during the period from 2005 to 2021. All patients were divided into three groups depending on the type of treatment: in group 1 (n=59) – the standard protocol of conservative therapy was supplemented with a course of hemosorption (HS); in group 2.1 (n=21) – left ventricular remodeling surgery was performed; in group 2.2 (n=6) – left ventricular assist device (LVAD) was implanted. During the study we analyzed patients’ clinical condition, the results of transthoracic echocardiography, complications and mortality: before treatment, by the end of in-hospital treatment and in the long-term period (12 months later). Statistical evaluation was performed using Student’s test and Pearson’s χ2 test (significance level p<0.05).
Results. After the therapy, all groups showed improvement of clinical condition of the patients by one NYHA class (p<0.05). There was an increase of left ventricular ejection fraction (LVEF) from 21.1±4.66 % to 34±2.59 % in group 1 and from 22.4±2.27 % to 35.65±5.25 % in group 2.1 (p<0.05). We also observed inverse LV remodeling with marked decrease of LV end-diastolic volume (LV EDV) and LV end-systolic volume (LV ESV) to 242.16±26.11 ml and 148.6±21.3 ml ( p<0.05) in group 1, to 228.75±20.5 ml and 141.5±17.5 ml (p<0.05) in group 2. 1 and a significant decrease in these indices in group 2.2 to 261, 2±103.56 ml (by 29.15%) and to 193±92.27 ml (by 36.23%) (p<0.05), respectively.
Conclusion. Extracorporeal and surgical methods of treatment of patients with severe HF against DCM background reliably improve their clinical condition and can be used in addition to the protocol of conservative therapy.
TWO-YEAR ANESTHESIOLOGY AND INTENSIVE CARE INTERNSHIP PROGRAM EFFICACY AND THE WAR INFLUENCE ON IT
Authors: BIELKA K. , KUCHIN I , KASHIY U. , FOMINA G.
Published: December 2022

COVID-19 pandemic and full-scale Russia aggression in Ukraine have become a challenge for the medical schools. Internships in anesthesiology and intensive care in Ukraine is three times shorter, comparable with high-income countries. The aim of the study was to evaluate the efficacy of the internship training.
A study was carried out at the department of surgery, anesthesiology and intensive care postgraduate education Bogomolets National Medical University named after O.O., Department of Surgery, Anesthesiology and Intensive Care Postgraduate Education. Among the most effective types of training, residents and teachers chose live practical classes, seminars and simulation trainings, self-study. The training efficacy of the Anesthesiology and Intensive Care internship program was acceptable for the anesthetic management of low-risk patients, but requires significant improvement for the anesthetic management of high-risk patients and the management of the critically ill.
Increasing mental toughness through COVID-19 gymnastics in adult people
Authors: Komarudin  , Paramitha Sandey Tantra , Ramadhan Muhammad Gilang , Novian Geraldi
Published: December 2022

The danger of this virus has forced the government to implement various regulations to reduce the level of spread and infection, one of which is by staying at home. Staying at home and staying away from socialization that is usually done makes individuals get various mental problems which of course have an impact on the human condition itself, so it is important for individuals to still have mental toughness. In this study, the authors wanted to examine the effect of implementing COVID-19 gymnastics that had been made previously on mental toughness in adults people in Indonesia. The experimental method with a one-group pretest-posttest design was used in this study. COVID-19 gymnastics for 6 weeks was given to 150 subjects by professional gymnastics instructors. Before and after being given treatment, the subject filled out the Mental Toughness Inventory (MTI) which was prepared beforehand to obtain data, after which data analysis was carried out using SPSS Version 24. The results showed that there was a significant effect of COVID-19 gymnastics on increasing mental toughness in adults people in Indonesia. In addition, the COVID-19 gymnastics was proven to be effective in providing an increase in results between the pretest and the posttest by 3.6%. This study concludes that the application of COVID-19 gymnastics has a positive effect on mental toughness in adults people in Indonesia, so it can be an alternative activity to avoid various mental health problems, especially during a pandemic like this. The author suggests that every individual remains active in exercising even in situations and conditions that are full of limitations, one of which can be done by doing COVID-19 gymnastics.
Light-controlled cell-free protein synthesis using phosphorothioate-caged antisense oligonucleotides
Authors: Hartmann Denis , Booth Michael
Published: December 2022

Cell-free expression of a gene to protein has become a vital tool applied in DNA nanodevices and synthetic cells. Antisense oligonucleotides are often used to induce gene knockdown; however, they have been underexplored for cell-free applications. Developing methods to non-invasively control gene knockdown with antisense oligonucleotides will be crucial for their precise regulation of cell-free biology and biotechnology. Here, we report a mild method for selectively attaching photoremovable protecting groups, photocages, onto phosphorothioate linkages of antisense oligonucleotides. Using this photocaging method, upon illumination, the original phosphorothioate antisense oligonucleotide is reformed. Photocaged antisense oligonucleotides, containing mixed phosphorothioate and phosphate backbones, showed a drastic reduction in duplex formation and RNAse H activity, which was recovered upon illumination. For the first time, we demonstrated that photocaged antisense oligonucleotides can be used to control cell-free protein synthesis. This technology will have future applications in light-activated biological logic gates and controlling the activity of synthetic cells.
pH-Dependent Conformational Switch Impacts Stability of the PsbS Dimer
Authors: Chiariello Maria Gabriella , Grünewald Fabian , Zarmiento-Garcia Rubi , Marrink Siewert-Jan
Published: December 2022

The photosystem II PsbS protein triggers the photo-protective mechanism of plants – nonphotochemical quenching (NPQ) – by sensing the acidification of the thylakoid lumen. A popular model of the NPQ activation involves the monomerization of the PsbS dimer. However, a clear connection between the PsbS pH-dependent structural changes and the dimer stability is still missing. Here, we apply a multiscale computational workflow including constant pH coarse grained (CG) and all-atom (AA) molecular dynamics simulations to investigate the structural response of the PsbS dimer to the pH variation. We find that most of the Glu residues undergo significant pKa shifts, in line with previous predictions for the monomeric state. Protonation of the key Glu173 residue induces the movement of an amphipathic helix, located at the dimeric interface, from the membrane to the aqueous environment, providing the first atomistic model of the PsbS dimer in its neutral pH conformation. Moreover, free energy profiles for the monomerization process, obtained with metadynamics simulations at the CG level, reveal that in the neutral pH conformation, where the network of H-bond interactions at the dimeric interface is destroyed, the protein-protein interaction is weaker. Taken together, our results show how the pH-dependent conformations of PsbS affect their dimerization propensity, which is at the basis of the NPQ mechanism.
Acyl Azolium-Photoredox Enabled Synthesis of -Keto Sulfides
Authors: Scheidt Karl , Rourke Michael , Wang Charles , Schull Cullen
Published: December 2022

a-Heteroatom functionalization is a key strategy for C–C bond formation in organic synthesis, as exemplified by the addition of a nucleophile to electrophilic functional groups such as iminium ions, oxocarbenium ions and their sulfur analogs, sulfenium ions. We envisioned a photoredox-enabled radical Pummerer-type reaction realized through the single-electron oxidation of a sulfide. Following this oxidative event, ⍺-deprotonation affords ⍺-thioradicals that participate in radical-radical coupling reactions with azolium-bound ketyl radicals, accessing a commonly proposed mechanistic intermediate en route to functionalized additive Pummerer products. This system provides a new and complementary synthetic approach to highly functionalized sulfurous products and beckons further exploration in C-C bond formations previously limited in the standard two-electron process.
Mechanochemical interconversion reactions of halogen-bonded cocrystals inspired by theoretical calculations
Authors: Kumar Lavanya , Leko Katarina , Nemec Vinko , Trzybiński Damian , Bregović Nikola , Cinčić Dominik , Arhangelskis Mihails
Published: December 2022

Periodic density-functional theory (DFT) calculations were used to predict the thermodynamic stability and the likelihood of interconversion between a series of halogen-bonded cocrystals. The outcomes of mechanochemical transformations were in excellent agreement with the theoretical predictions, demonstrating the power of periodic DFT as a method for designing solid-state mechanochemical reactions prior to experimental work. Furthermore, the calculated DFT energies were compared with experimental dissolution calorimetry measurements, marking the first such benchmark for the accuracy of periodic DFT calculations in modelling transformations of halogen-bonded molecular crystals.
libkrylov, a Modular Open-Source Software Library for Extremely Large On-the-Fly Matrix Computations
Authors: Rappoport Dmitrij , Bekoe Samuel , Mohanam Luke Nambi , Le Scott , George Naje' , Furche Filipp
Published: December 2022

We present the design and implementation of libkrylov, an open-source library for solving matrix-free eigenvalue, linear, and shifted linear equations using Krylov subspace methods. The primary objectives of libkrylov are flexible API design and modular structure, which enables integration with specialized matrix--vector evaluation “engines”. Libkrylov features pluggable preconditioning, orthonormalization, and tunable convergence control. Diagonal (conjugate gradient, CG), Davidson, and Jacobi--Davidson preconditioners are available, along with orthonormal and nonorthonormal (nKs) schemes. All functionality of libkrylov is exposed via Fortran and C application programming interfaces (APIs). We illustrate the performance of libkrylov for eigenvalue calculations arising in time-dependent density functional theory (TDDFT) in the Tamm--Dancoff approximation (TDA) and discuss the convergence behavior as a function of preconditioning and orthonormalization methods.
Psödotümör serebri ve Chiari malformasyonu Tip 1 birlikteliği
Authors: TEN Barış , BAĞDATOĞLU Celal , YÜKSEK Hasan Hüsnü , TEMEL Gülhan , BALCI Yüksel
Published: December 2022

Amaç: Amacımız Psödotümör serebri ve Chiari malformasyonu Tip 1 birlikteliğinin tanısı için farklı radyolojik belirteçler bulabilmektir. Yöntem: 2007-2020 tarihleri arasında radyoloji anabilim dalına Chiari malformasyonu Tip 1 klinik ön tanısıyla yönlendirilip magnetik rezonans görüntüleme ile radyolojik olarak tanısı doğrulanan hastalar geriye dönük olarak değerlendirildi. Hem servikal hem serebral tetkikleri bulunan 49 Chiari malformasyonu Tip 1 hastası ve aynı yaş ve cinsiyetten olan Chiari malformasyonu Tip 1 tanısı olmayan 49 kontrol grubu çalışmaya dahil edildi. Chiari malformasyonu Tip 1 tanılı hastaların Serebral MRG görüntülerinden radyolojik olarak Psödotümör serebri varlığı, Servikal spinal MRG görüntülerinden şiringomyeli varlığı, McRae çizgisine göre serebeller tonsillerin ve obexin mesafesi milimetre cinsinden değerlendirildi. Bulgular: Chiari malformasyonu Tip 1 klinik ve radyolojik tanılı olgularda radyolojik olarak Psödotümör serebri tanısı konulan hastaların konulmayanlara göre serebeller tonsilleri ve Obexi daha aşağı yerleşimlidir ve siringomyeli eşlik etme oranı daha fazla gözükmektedir. Ancak her iki grup arasında istatistiki olarak anlamlı bir farklılık izlenmemektedir. Sonuç: Psödotümör serebri ve Chiari malformasyonu Tip 1 birlikteliği tahmin edildiğinden daha sık görülmektedir. Psödotümör serebri ve Chiari malformasyonu Tip 1 birlikteliğinde tedavi protokülünün farklı olması bu birlikteliğin tanısını koyabilmenin önemini arttırmaktadır. Psödotümör serebri ve Chiari malformasyonu Tip 1 birlikteliğinin tanısında farklı radyolojik belirteçler bulabilmek için daha fazla sayıda radyolojik görüntüleme çalışmalarına ihtiyaç vardır.
Sistem Informasi Perpustakaan Menggunakan Microsoft Visual Basic 2010
Authors: Rokhim Irfan Zidnir
Published: December 2022

TBM Griya Pustaka is the only TBM in Ngemplak Mranggen Demak village. The use of books in the process of inventory and management of the library is very unmanageable and tends to be long in service to the community. Therefore, an adequate library information system is needed, to process book searches automatically and generate information quickly and precisely. The development of the existing information system in the TBM Griya Pustaka Library will be created using Microsoft Visual Studio 2010 and using the Software Development Life Cycle (SDLC) method in the development of the system. The resulting application can help the recording process with the automation of lending, returns, lending requests as well as help speed up the book search process for library members.

TBM Griya Pustaka merupakan satu-satunya TBM di desa Ngemplak Mranggen Demak. Penggunaan Buku dalam proses inventori dan manajeman perpustakkaan sangat tidak tertata dengan rapi dan cenderung lama dalam pelayanan terhadap masyarakat.  Oleh karena itu dibutuhkan sistem informasi perpustakaan yang memadai, untuk memproses  pencarian buku  secara otomatis dan menghasilkan informasi yang cepat dan tepat.Pengembangan sistem informasi yang ada pada Perpustakaan  TBM Griya Pustaka akan dibuat dengan menggunakan  Microsoft Visual Studio 2010 dan menggunakan metode Software Development Life Cycle (SDLC) dalam pengembangan sistemnya. Aplikasi yang dihasilkan dapat membantu proses pencatatan dengan otomatisasi peminjaman, pengembalian, permintaan peminjaman serta membantu mempercepat proses pencarian buku untuk anggota perpustakaan.
Greenwashing and investment attractiveness of companies for «green» investments to the national economy
Authors: Makarenko I.O. , Kremen V.M. , Vorontsova A.S. , Kostenko O.N. , Makarenko S.N.
Published: December 2022

Greenwashing appears as an understudied category in the context of transparency, investment attractiveness of companies for making green investments. The purpose of the study is to identify greenwashing and model its impact on the investment attractiveness of Ukrainian companies in the context of green investments. For this purpose, identification of greenwashing and its influence on investment attractiveness was carried out for Ukrainian agriculture companies. Two-stage PLS-SEM modelling was used as a methodology. Taking into account the consistent research / modelling the relationships of explicit and latent variables, which allow us to detect greenwashing and describe its impact on the investment attractiveness of agrarian companies, which is determined at the operational and financial levels, the modelling results indicate the need for agricultural companies to focus on building the potential for long-term financial investments, the formation of a holistic regulatory environment regarding its activities in the field of sustainable development, as well as the regularity of information disclosure. Based on the identified factors that determine the impact of greenwashing on the investment attractiveness of leading agricultural companies of Ukraine, recommendations have been developed to minimize its signs and increase such attractiveness for investors in the context of the post-war recovery of the agricultural sector on the basis of sustainable development, overcoming the food and energy crisis and the European integration green transition.
The Development Of Economic Potential Of People In Pandemic Through Earning Zakat Distribution
Authors: Arwani Agus , Salenussa Stenly , Rahayu Nurul Widyawati Islami , Faiz Muhammad Fauzinudin , Cakranegara Pandu Adi , Aziz Abdul , Andiyan Andiyan
Published: December 2022

Purpose: This research aimed to ascertain the people's economic progress throughout the pandemic via the distribution of productive zakat by BAZ/LAZ in Pekalongan.
 
Theoretical Framework: Zakat has evolved as a tool for economic growth and poverty reduction among the peoples of the regions during times of economic distress (Yusroni & Chadhiq, 2021). Zakat provides several benefits over the standard fiscal tools now available. Numerous ideas and theories have been advanced by specialists to address the issue of poverty (Alaro & Alalubosa, 2019; Iqbal & Mirakhor, 2011). However, not all ideas can be implemented and contribute to poverty reduction. It is anticipated that professional zakat administration and profitable usage would enable poverty reduction (Hoque, Khan, & Mohammad, 2015).
 
Design/Methodology/Approach: Field research with a qualitative approach collects, manages, and distributes zakat funds, incredibly productive zakat at BAZ/LAZ in Pekalongan City. The technique is triangulation.
 
Findings: The results showed that BAZ/LAZ in Pekalongan City had implemented effective zakat distribution programs, namely BAZNAS, LAZ Al Ummah, LAZISMU, and LAZ Central Java, while LAZINU had not implemented the effective zakat program optimally. In general, BAZ/LAZ in Pekalongan City used productive zakat to promote the potential of the people via various sorts of productive zakat initiatives throughout the pandemic. The primary objective of productive zakat is similar to that of BAZ/LAZ in Pekalongan City. According to defined protocols, the productive zakat distribution model is carried out precisely and accurately.
 
Research, Practical & Social Implications: Despite several challenges, the distribution of productive zakat continued throughout the COVID-19 epidemic. The effective zakat program emphasizes developing diverse models via creativity and innovation for people's economic growth to avoid poverty.
 
Originality/Value: The findings of the model of economic development of the people run by the mustahik also vary in the efforts carried out whose main objectives are to save, infaq, and develop businesses to avoid the problem of poverty.
A Study on Influence of Personal Profile Variables on Emotional Intelligence Ofarts and Science College Students
Authors: Sathya A. , Velmurugan V. P.
Published: December 2022

Purpose: To assess the level of emotional intelligence among Arts and Science College students as well as the influence of personal profile traits on emotional intelligence in those students.
 
Theoretical framework:  Variables like Education, Area of residence, Gender, Age, Family monthly income, Father Educational Qualification influence the Emotional Intelligence of the Students
 
Design/methodology/Approach:   Purposive sampling, T- test, F- Test
 
Findings: This research has added to the body of knowledge about emotion-related personality differences among arts and science college students studying in various streams, and how they differ in various ways
 
Research, Practical  &  Social  Implications: Emotional intelligence should be taught through various workshops, Community-wide awareness programmes should be organized
 
Originality/Value: Establishing Emotional Intelligence-based results across several streams can aid in achieving a better balance between a student's personality and their academic stream of choice. Academic success and professional advancement are made easier with this balance. Emotional intelligence testing may also aid in the development of self-reflection and increased understanding of one's own personality.
Future team leadership and empowerment in the performance of measuring virtual team productivity with information technology
Authors: Aarthi G. , Sujatha S.
Published: December 2022

Purpose: The purpose of this paper is to examine the virtual teams effectiveness in productivity, whether leadership and Empowerment with the relevant factors influencing the virtual team productivity are not. This study examines the virtual group in IT enterprises and their authority and strengthening of efficiency of a virtual group.

 

Theoretical framework:  An essential method for directing business for associations to stay serious and support in a global environment. What's more, that is used in numerous kinds and sizes of associations either as a key unit or as a supporting unit. Virtual groups in Indian programming organizations stand out explicitly inside the world wide IT service sector.

 

Design/methodology/approach: The present study is conducted by designing the set of questionnaires with respect to the leadership and empowerment of a virtual team and the performance of virtual team factors. And it is distributed to the organization, which uses a virtual team. The questionnaires were distributed to the 300 participants; only 257 responses are received from the company. From the 300 respondents, 43 responses were rejected because the response is not clear, so a total of 257 responses are taken. By using a 5-point Likert scale, the questionnaire was prepared.

 

Finding: The relationship between the team effectiveness, team performance, and empowering the leadership of the hypothesis are empirically tested. The result indicated that the empowerment and leadership of a virtual team enhanced the performance and productivity of a virtual team.

 

Research, Practical & Social Implication: The paper contributes to a better understanding of the internal processes within a virtual team in order to develop the effectiveness through Leadership and empowerment which increase the productivity.

 

Originality/value: Notwithstanding the inescapability of overseeing virtual groups, associations find it especially provoking for virtual colleagues to display and deal with their initiative ways of behaving.
EXPERT SYSTEM TO GUIDE USERS OF THE TOURIST CORRIDOR OF THE PROVINCES OF JAEN, SAN IGNACIO AND UTCUBAMBA IN CAJAMARCA, PERU
Authors: Arce Fernandez Nilthon , Gutierrez Segura Flabio , Escobar Gómez Eder , Díaz Ruiz Adán , Piedra Tineo José , Lujan Segura Edwar
Published: December 2022

Purpose: Develop a rule-based expert system to guide the users of the tourist corridor of the provinces of Jaén, San Ignacio and Utcubamba (Peru).

Theoretical framework: Hussein and Aqel (2015), developed a rule-based expert system in Jordan to choose the best tour package based on time, budget, and preferences. In Peru, Ramos and Valdivia (2017), proposed an expert system to promote tourism in the Lambayeque region.

Methodology: To develop the system, the methodology of Nicolás Kemper was used. Tourism experts from the provinces participated in the development of the knowledge base. The evaluation was carried out with an expert different from those who prepared the aforementioned base.

Findings: In the evaluation, the expert system and the human expert agreed on the recommendation of tourist attractions by 80%. Concluding that this system helps tourists in making decisions about which places to visit in the tourist corridor.

Contributions: The system helps improve the dissemination of local tourist information. To develop the knowledge base, tourism resources were systematized. New variables can be incorporated into the knowledge base in order to obtain more personalized tourist recommendations.

Originality/value: This research is innovative because there is no expert system to guide tourists who want to travel to these places; it has social relevance as it helps to boost the local economy.
A relationship between service quality and customer satisfaction in e-banking services- a study with reference to commercial banks in Chennai City
Authors: Shanmugam RM , Chandran M
Published: December 2022

Purpose: This paper's main aim is to validate the service quality dimensions offered by commercial banks in the study area and the relationship between service quality dimensions and customer satisfaction provided by commercial banks.
 
Theoretical Framework: In India, three categories of commercial banks are the public sector, private sector, and foreign banks. These banks have heavy competition among themselves in maximising their customer base.
 
Design/Methodology/Approach: The researcher collected 600 responses through convenience sampling. Applied exploratory factor analysis, confirmatory factor analysis, regression analysis and structural equation model to conclude that service quality of electronic banking service is not a unique phenomenon.
 
Findings: E-Banking depends upon the five essential factors: reliability, safety and security, assurance, technological augmentation, and quickness since the electronic banking services offered by commercial banks are entirely based on the Internet process.
 
Research, Practical & Social Implications: The study identifies the customer requirements and how commercial banks could satisfy such requirements with their banking strategies. Also, the study identifies whether any demographic difference exists among the customers of commercial banks in perceiving the quality of e-banking services.
The Impact of Dumping Policy on the Food Gap of Chicken Meat in Iraq For the Period (2004-2019) - Turkish Imports Of Chicken Meat a Case Study
Authors: Majeed Omar Hameed , Farhan Mohammed Noori , Salloum Taameem Mohamed
Published: December 2022

Purpose: As a result of the sudden and ill-considered trade openness of Iraq after 2003 to the countries of the world in general and the neighboring countries in particular, and in the absence of the necessary support for the national productive forces and the lack of effective standardization and quality control devices, this led to the exposure of most local products, especially agricultural ones, to decline and inability On the competition and thus dumping the Iraqi market, especially the agricultural products, with imported products, this study came to find out the effect that dumping has on the local production of chicken meat and the impact of that impact on the size of the food gap, and whether the results of the practical study will be in accordance with the logic of economic theory.
 
Theoretical framework: The concept of dumping, its causes and the difference between it and competition, the WTO position of dumping, and the concept of the food gap were also discussed.
 
Design/methodology/approach: The data was collected from its official sources, and then the mathematical equations were developed according to economic theory and logic, and using the (EViews) program, the final results were obtained, which were compatible with the logic of economic theory.
 
Findings: The results of the study proved that when the dumping of chicken meat increased by (1%), the food gap of chicken meat increased by (5.1%).
 
Research, Practical & Social implications: This study contributes to proving the negative impact of dumping resulting from commercial exposure or unstudied commercial openness, and thus its impact on the food security of the Iraqi community.
Originality/value: This research is the first of its kind in the field of agricultural economics, as it links the food gap and dumping policy in a theoretical and practical way.
The panel data regression : relationship of the exports, imports and intake of oil reserves son oil production levels in southwest asian countriesto contribute to state revenue (The implement of International Trade Theory)
Authors: Rahman Abdul , Muda Iskandar , Caroline Caroline , Panjaitan Putri Damayanti , Situmorang Rama Yolanda
Published: December 2022

Purpose :The paper aims to test the connectionthe exports, imports of oil reserves at Southwest Asia in 2016 to 2019. The data used is secondary data from 8 countries in Southwest Asia, obtained from databank.worldbank.org.
 
Theoritical Framework :The panel data combination from the same partial observed withThe Common, Fixed and Random Effect Model test.
 
Design/Methodology/Approach :The relationship and compile the percentage modeling of exports, imports, and refining intake to the level of oil production in Southwest Asian countries. The eviews software data processing application. Due to the increasing world oil demand, it is necessary to know the estimated level of oil production in the 2016 to 2019 period. Based on these conditions, variable assumptions that affect each other are used, namely exports, imports, and exports. distillation intake through  approaches.
 
Findings :The production and the independent variable has a relationship with each other. Through t-statistical test data, import variables (X1), export variables (X2), oil reserves intake variables(X3) through hypotheses H0 (no effect) and H1 (influence), show a probability of less than 5% which has a significant effect on production (Y) oil in West Asia.
 
Research implication :The results of this study contribute to and support The International Trade Theory.
 
Practical implication :When a country can establish friendship, it is possible to happen as in the political, cultural, educational, and so on. So indirectly it can help meet the needs in other sectors besides the economy.
 
Social implication :The benefits that can be received by countries from international trade are increased prosperity and increased social status. Prosperity can be observed from the economic activities carried out by producers, consumers, and the government who both benefit. All three of them felt the prosperity of this activity.
 
Originality/Value : The peculiarity of this research is that it examines selected Asian countries that have not been carried out in previous studies and proves the robustness of the International Trade Theory.