bluuebunny/crossref_metadata_2025 huggingface dataset:
Current Advance and Future of mRNA Vaccine in Cancer Therapy
Authors: Li Yutung Wendy
Published: October 2024

After years of development, cancer vaccines have gradually become an important part of tumor immunotherapy, and have shown a more rapid development momentum under the background of the current era. The vaccine has the advantages of high efficiency, safety, rapid development potential, cost-effectiveness, etc. In recent years, with the continuous improvement of mRNA technology, relevant technologies in the field of mRNA molecules have also made breakthrough progress, and mRNA vaccines have achieved certain results in cancer treatment. Compared with traditional vaccines, mRNA vaccines can induce the body to produce humoral immunity and cellular immunity at the same time, and the research and development cycle is short, the cost is low, and it can quickly develop candidate vaccines to deal with virus mutation, which is conducive to cancer control. mRNA vaccines have become a current research hotspot and have wide application prospects in the prevention and treatment of tumors and infectious diseases. This article comprehensively discusses the structural characteristics, types, unique advantages and future prospects of mRNA vaccines, in order to help understand the vaccine function and clinical application of mRNA, provide a direction for the development of mRNA drugs, and expect that mRNA cancer vaccines will be used in clinic as soon as possible to benefit patients.
Analyzing The Investable Value of Five Automotive CompaniesThrough Financial Data and Data Mining Techniques
Authors: Wang(Eric Wang) Wenrui
Published: October 2024

Automobile industry is a capital-intensive, technology-intensive modern industry, after more than a hundred years of development and evolution, the automobile manufacturing industry has formed a huge industrial chain, becoming one of the world’s largest and most important industries with the highest output value. In this research, I selected five world-famous automobile brand companies, stands for Ferrari, Bentley, Mercedes-Benz, Porsche, and Rolls-Royce. With reference to the operating financial data such as balance sheets, income statements, cash flow statements, year-end market share values, etc. of these five companies for the years 2021-2023, several financial ratios are used for comparative analysis and Ferrari is recommended as a company with the most promising investment outlook.
Intervention in the Treatment of Substance and Behavioral Addiction in Adolescents based on Motivational Interviewing: A Literature Review
Authors: Zhao Mengzhen , Yang Lihong , Guo Yinuo
Published: October 2024

Motivational Interviewing (MI) is a customer-centered treatment method, encouraging users’ behavioral change. The principal rules consist of empathy expression, discrepancy creation, resistance adaptation, and self-efficacy enhancement. This review examines MI’s application in adolescent substance and behavior addiction management, assessing its impact on increasing therapy engagement, curtailing addictive behaviors, improving peer relationships, and addressing coexisting mental health conditions from an ecosystem perspective based on personal perspective and psychology, family influence, peers and social environment. Findings demonstrate that MI significantly ameliorates adolescent addiction over both short-term and long-term periods. Future research should focus on cultural adaptation, implementation, training, managing comorbid cases, and evaluating long-term outcomes.
Developing a Photoacoustic Probe for in vivo Tumor pH Detection by Gaussian calculation
Authors: Qin Zhancheng
Published: October 2024

pH dysregulation is a major feature of cancer, and the development of advanced photoacoustic probes capable of monitoring pH is important for both diagnosis and treatment of cancer. Previous work (done by Tijana Jokic’s group) found that aza-BODIPY molecule has better photoacoustic properties and this was investigated in depth, leading to the development of new pH probes, but the functionality of the molecule can be upgraded again if the photoacoustic properties of the molecule can be further expanded, while the maximum wavelength of the molecule can be further extended to fit the commercial range. This study optimized the previous molecule based on the Gaussian program, and the new molecule with NO2 attached to R4 showed the best properties in which the maximum excitation wavelength reached 770.85 nm.
Text Comment Classification and Sentiment Analysis Model Based on LSTM
Authors: Huang Chengbin
Published: October 2024

This study addresses the challenge of sentiment analysis and text classification in user-generated comments, an essential task for understanding public opinion in the digital age. With the widespread adoption of social media, the sheer volume of text data has increased exponentially, thereby necessitating advanced analytical tools. The study integrates Long Short-Term Memory (LSTM) networks with attention mechanisms to develop a model adept at both classifying and analyzing the sentiment of textual comments. The research methodology commences with data cleaning, tokenization, and feature extraction, subsequently followed by the implementation of a bidirectional LSTM architecture augmented with an attention mechanism. The model underwent rigorous training and testing on a comprehensive dataset, yielding high accuracy rates in sentiment analysis and text classification. The results underscore the model’s proficiency in capturing sentiment nuances and underscore its potential for deployment in e-commerce and content recommendation systems, emphasizing the practical implications of this research for enhancing decision-making processes in businesses and among policymakers.
Comparative Study on Pigment Components (Flavonols and Anthocyanins) and Antioxidant Capacity in Different Colored Double-petal Lotus
Authors: Xu Zirui
Published: October 2024

Lotus, an edible flower with high ornamental values, takes forms in many sizes, shapes, and colors. Among which, double-petal lotus not only has higher ornamental values but also gives a yield advantage in exploitation due to the large number of petals. Flower color is an important ornamental indicator, and flavonoids are the key basis for color presentation as well as important active components in lotus. This research used petals of four different colored double-petal lotus cultivars to identify their petal color, pigment localization, and pigment components (flavonols and anthocyanins), as well as the antioxidant activity of the petal extraction solution using the ABTS method. It was discovered that the white YMQ was the brightest but had the lowest Chroma and the third-highest Hue angle, while the dark red WFMH was the darkest but had both the highest Chroma and Hue angle. Most of the colored pigments were located in all the thin-walled cells immediately adjacent to both the upper and lower epidermis. The yellow MLQS had the highest amount of Quercetin derivatives in flavonols but the lowest antioxidant activity, the dark red WFMH had the highest amount of anthocyanin, and the pink MDZ had the highest antioxidant activity. This research offers insights into the potential medical usage of certain double-petal lotus cultivars like MLQS and WFMH, hopefully providing a reference for the identification of raw materials for extracting pigments to improve sleep patterns and prevent Alzheimer’s Disease.
Analyzing the Alibaba-Suning Partnership: Strategies and Outcomes
Authors: Shi Yihao
Published: October 2024

This paper deeply discusses the strategic cooperation between Alibaba and Suning Yunshang, and analyzes its strategic significance and cooperation results in the context of new retail. By sharing resources and complementing each other’s strengths, the two sides have built a new retail ecosystem integrating online and offline, and realized the all-round interoperability of goods, services, technologies and data. This cooperation has not only promoted the rapid growth of the two sides’ business, but also promoted the deep integration of the retail industry and the Internet industry, providing a strong reference for the future development of e-commerce and retail industry in China and even the world. The strategic partnership between Alibaba and Suning Yunshang represents a significant milestone in the evolution of new retail, where online and offline channels converge to create a seamless consumer experience. By leveraging each other’s strengths—Alibaba’s robust e-commerce platform and Suning’s extensive offline retail network—the two companies have fostered a new retail ecosystem that integrates goods, services, technologies, and data across both platforms.
Hippocampal Synaptic Plasticity Reduction Leads to Decreased Resilience to Depression and Anxiety in the ASCL-Mouse Model
Authors: Qiu Haotian
Published: October 2024

A substantial body of research has been conducted with the objective of elucidating the role of synaptic plasticity in the aetiology of depression and anxiety. Despite the fact that numerous existing tests have demonstrated a correlation between neuroplasticity and depression, the precise role of synaptic plasticity remains unclear. The objective of this experiment is to elucidate the impact of hippocampal synaptic plasticity on resilience to depression and anxiety. The experiment comprises a preliminary test and a series of main experiments. The preliminary tests are conducted to eliminate the potential effects of apoptosis caused by the BAX gene. The main experiments then assess anxiety and cognitive levels by dividing subjects into multiple groups and administering a battery of tests. In a 40-week period, the mice will be modified and will experience major depression as a result of an 8-week UCMS treatment.
Can Whole-heart Tissue Engineering Products by Recellularization from Scaffolds Be Utilized on Humans in the Next Ten Years?
Authors: Gao Naitian
Published: October 2024

Diseases like organ failure lead to irreversible damage to our body, making organ transplantation the only treatment. However, though organ transplantation may be an effective treatment, problems of organ shortage and post-transplantation immune rejection still remain unresolved, making the development of alternative technologies vital. Organ regeneration is, therefore, a promising treatment as it aims to lower the chance of immune responses and may potentially solve the issue of organ shortage. An average procedure of organ regeneration has two steps: decellularization and recellularization. Decellularization techniques include physical, chemical, and enzymatic treatments, and these methods are often combined to maximize cell depletion, turning the organ into an extracellular matrix scaffold and minimizing the chances of immune rejection. Recellularization is the process of repopulating the scaffold with patient-specific cells, and is often completed through using perfusion systems by performing vascular perfusion and intramyocardial injections with the help of a bioreactor. This article explains the concept of whole-heart regeneration and assesses different methods of decellularization and recellularization to find the treatment with the highest efficacy and efficiency, while also conducting a case study on cultured epidermal autografts and primary research, in the form of a questionnaire, to look at the social acceptance of this technology, estimate the progress of whole-heart regeneration, and discuss its limitations.
Application of Dietary Anthocyanins in Type 2 Diabetes Mellitus Treatment
Authors: Hu Jinyang
Published: October 2024

Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by impaired glucose control around the world that causes huge health challenges globally with increased morbidity and mortality. Inadequate insulin secretion and decreased insulin sensitivity are considered as main contributors to T2DM. Anthocyanin, a type of flavonoid compound, is one potentially feasible dietary intervention for T2DM treatment in addition to clinical drug interference. Dietary anthocyanins can be found in various berries, vegetables, and beverages, which provide vibrant colors. Anthocyanins are also increasingly used as colorants in the food industry. It is also seen as a supplement because of its antioxidation properties. Meanwhile, several evidence demonstrate the potential relationship between dietary anthocyanin intake and T2DM management. In this work, recent epidemiologic studies on the potential effects of anthocyanins in controlling T2DM have been reviewed, especially focusing on the typical indexes such as glycemic levels, insulin levels, etc. Many studies illustrate that appropriate intake of dietary anthocyanins could control glycemic levels, adjust insulin levels, and reduce insulin resistance. Because of these functions, dietary anthocyanins may trigger positive effects on T2DM treatment. Dietary anthocyanins could be seen as a good dietary intervention in T2DM control that meets the requirement of long-term management for the specific chronic disease.
Anti-inflammatory response controlled by gamma wave
Authors: Mu Junhao
Published: October 2024

It is now believed that the cause of Alzheimer’s disease is the accumulation of amyloid-Bata, which is caused by a variety of factors, such as neuroinflammation. So in this study, the researchers will study the changes of microglia from M1 to M2 by changing the frequency of gamma wave. If microglia change from M1 to M2, that means it changes from pro-inflammatory to anti-inflammatory.
Explore the Problems and Optimization Countermeasures Existing in the Marketing Hype of the Shoes’ Business
Authors: Zhong Jiahang , Zhu Le
Published: October 2024

This paper discusses the phenomenon of shoe marketing hype and its impact on consumer behavior and the market. First of all, through the development trend of social media and online platforms, the affected aspects of consumers are analyzed in this paper. Through the Nike brand, the price of limited edition sneakers has risen to a very extreme number, which discusses the reasons for this factor, including the cooperation between the spokesmen and the brand, thus causing consumers’ enthusiasm for limited edition sneakers, and analyzes the psychology of consumers. Consumer psychological factors mainly include the negative factors of the scarcity of goods. The paper emphasizes supply chain management to maintain the balance of the market and not oversaturation to ensure the scarcity of shoes and uniqueness in the market. In addition, the special commodities represented by sneakers will also be symbolic, stored, circular, and speculative, representing the uniqueness of the product online. In the end, the problems in the market are explained and optimized, and suggestions are put forward, such as advocating the concept of healthy consumption and encouraging consumers to choose products according to their actual needs rather than pursuing the value of hype.
Research of Design Technology of Printed Circuit Board
Authors: Yan Ziao
Published: October 2024

This paper delves into various methodologies for enhancing the quality, design, and optimization of Printed Circuit Boards (PCBs). With the development of the technology, the importance of Printed Circuit Board(PCB) is recently mentioned by more and more people who is trying to make progress of human technology. The classification of PCB defects, a crucial step in ensuring product reliability, is discussed on several categories of defects in PCB, highlighting recent advancements such as fuzzy c-means segmentation, which significantly improves defect detection accuracy. When producing, the layout is quite significant. In a conference, a group of scientists used a thermal layout modelling and optimization routine to make the board having more space to put circuit on it. Methods to ensure PCB quality during production are examined, focusing on optical and electrical testing. The PCB design process is also explored, emphasizing the importance of those considerations before production. Finally, the paper reviews innovative approaches to PCB layout optimization, particularly in managing heat dissipation and dynamic behavior through advanced simulation techniques.
Construction of Metal Ion Composite Materials and Their Autophagy Activation to Control the Growth of Malassezia on the Skin
Authors: Jiao Ziyan
Published: October 2024

Malassezia can cause various skin diseases, and even lead to more severe problems for specific populations such as immunocompromised children and adults, people with high sebum secretion, and patients with gastrointestinal diseases. In recent years, a plenty of research has indicated that traditional antifungal treatment methods may lead to drug resistance problems. Due to the traditional methods causing this problem, there is an urgent need for new methods to treat Malassezia induced diseases. Metal ions have been utilized in biology, chemistry, and medicine. Existing studies have shown that certain metal ions have bactericidal effects, requiring specific metal ions to be selected for different situations. Here, a method to activate autophagy through copper and iron ions has been proposed. This study focuses on the construction of novel metal ion-conforming materials and their role in activating autophagy in Malassezia, developing composite materials based on metal ions to control the growth of Malassezia.
The Emerging Role of gut Microbiota in Immunotherapy
Authors: Zhao Lingke
Published: October 2024

The gastrointestinal tract contains a diverse and dynamic population of microorganisms called the gut microbiota, which is essential for immune system regulation. Recent studies have highlighted that gut microbiota has a major influence on the effectiveness of cancer immunotherapy, particularly immune checkpoint antagonists. This review explores the mechanisms of specific gut microbiota, such as Bifidobacterium and Lactobacillus, to enhance innate and adaptive immune responses, including activation of dendritic cells, polarization of macrophages, and stimulation of CD8+ T cells. In addition, this review discusses therapeutic strategies aimed at manipulating the gut microbiota to enhance the effects of immunotherapy, including fecal microbiota transplantation (FMT), probiotics, and engineered microbiota. Although these approaches have promising potential, the challenges still remain with the variability of patients and microbiota manipulation. This review emphasizes how crucial it is to combine immunotherapy and the gut microbial community to create more individualized, effective cancer treatments, which will eventually improve patient outcomes and advance the area of cancer treatment.
The Role of Photography in Breaking News Events: The Trump Assassination as an Example
Authors: Sun Chuqiao , Wei Xiangyun , Xu Zhaojun
Published: October 2024

This paper explores the role of photography in breaking news events through photographs taken by Evan Vucci during the Trump assassination. Using content analysis, the study analyzed 105 public articles to explore the visual guiding power of photography and how the media uses images to influence public opinion. The study found that photography can quickly attract public attention and influence the emotional level, while media can shape a specific narrative framework through selective display. The life of a news report lies in vividness, truth, and vividness. The same is true of news photography. Capturing real moments with both visual and emotional impact is the best news photo [1]. Meanwhile, it points out the shortcomings of China’s WeChat in reporting, such as ignoring the victims and the deep-rooted causes, and suggests that the media should reflect on the problems in reporting and take social responsibility. The study also offers suggestions for future reporting practices, emphasizing the key role of photojournalism in shaping public perception and the importance of media ethics. The limitation of the study is that the sample mainly focuses on WeChat, with a short timeframe, and future research will expand the sample and deepen the analysis of the audience’s psychological and emotional responses.
Living in the Digital Age: AI Technology and the Changing Lifestyle of the Elderly
Authors: Wang Zhongshi
Published: October 2024

As technology advances, diverse artificial intelligence products are invented and put into use. While dramatically improving the quality of human life, digital technologies are also changing the lifestyles of different groups to varying degrees. Focusing on the elderly population, this study utilizes a combination of questionnaire, interview, and documentary research methods in hopes of collecting information in a broad and comprehensive manner. The study mainly focuses on how AI technologies in the digital age are changing the lifestyles of older people and the potential factors that lead to such changes. The study reveals that the digital age has a dual impact on the lives of older people. Thanks to the intelligence and simplicity of AI technology, older people’s lives have become much more efficient and convenient. However, the expensive price of AI devices and products, which also keeps some older people from enjoying the convenience of technological inventions, prevents them from integrating into the digital society. Among many lifestyles, changes in home-based lifestyles are the areas of greatest change in the lifestyles of the elderly in the digital age. These changes are mainly influenced by social, technological and personal factors. The present study expresses ample social concerns for the elderly population. It also conducive to helping older people fully integrate into a smart and convenient life and equally enjoy the dividends of the digital age.
SingStress: Sensor Analysis in Acute Psychological Stimulation
Authors: Jin Fan , Chen Yuhang , Zhang Xiaowen , Chen Yifeng , Meng Bolun
Published: October 2024

Acute stress results in significant risks to the cardiovascular and immune systems, so monitor and manage effectively is important. Existing studies frequently utilize sensors such as photoplethysmography (PPG) and electrodermal activity (EDA) to monitor and evaluate stress, however, they often miss to compare the sensitivity of these sensors. In this experiment, we collected PPG and EDA data from 26 participants during resting and public speaking tasks. Participants were also asked to complete a stress-related questionnaire. Pearson’s correlation coefficients were calculated from the analysed data and questionnaire score. The results indicate that for the male group, the correlation with stress for PPG sensors ( ρSH = 0.5796 ) was stronger than for EDA sensors (ρSR = 0.1036 ). Oppositely, for the female group, EDA sensors showed a stronger correlation with stress ( ρSR = 0.6265 ) compared to PPG sensors ( ρSH = 0.2093 ). These findings suggest that PPG sensors are more sensitive for male students, while EDA sensors are more sensitive for female students.
Caught in Transition: Dynamics of Waithood Among Chinese and Japanese Youth
Authors: Jiang Tian
Published: October 2024

This paper investigates the dynamics of waithood among Chinese and Japanese youth, focusing on the unique aspects experienced in each country. Waithood, a period of prolonged transition into adulthood due to delayed milestones like stable employment and marriage, is increasingly prevalent due to high unemployment rates and evolving job markets. This paper presents the mental and social strain those experiencing waithood must endure, and examines government efforts to address these issues, comparing and contrasting the strategies implemented in China and Japan. Despite various initiatives, the findings suggest that current measures are insufficient to fully alleviate the challenges faced by young people. The paper argues for more comprehensive policies that address the root causes of waithood, emphasizing the need for innovative approaches to support youth in achieving independence. This research contributes to a deeper understanding of youth transitions in East Asia and underscores the urgency for effective interventions.
Estudio morfológico de la artesanía alfarera en la parroquia La Victoria, comuna El Calvario, Cotopaxi – Ecuador
Authors: Guerra Aupaz Anahí Esther , Lanas López Manuel Enrique
Published: October 2024

Mediante el estudio morfológico, este artículo se enfoca en rescatar el valor, significado y aplicación de las piezas alfareras elaboradas artesanalmente, las cuales contienen variedad de diseños, formas, colores y conceptos que se analizan a través de la metodología iconológica e iconográfica de Erwin Panofsky. Obteniendo la información necesaria, se comprende la importancia de la producción artesanal y el valor que se debe implementar para reconocer la riqueza cultural de la comunidad a través de la generación de estructuras modulares como propuestas significativas extraídas de los mismos diseños ya establecidos para fortalecer el significado y valor de identidad en las piezas alfareras. Existiendo el avance tecnológico como maquinaria avanzada, el valor e historia de los productos artesanales que se ha ido realizando desde las primeras generaciones culturales en la zona, ha llegado a deteriorarse; esta pérdida ocasiona un desglose histórico, donde la importancia cultural identitaria de la alfarería queda en el olvido y su producción corre el riesgo de desaparecer. La tradición alfarera mantiene vivo el patrimonio y la producción artesanal en el Ecuador, donde se estudia a El Calvario, comuna perteneciente a la parroquia La Victoria del cantón Pujilí; además, se destaca la elaboración de piezas artesanales como productos utilitarios, decorativos, acabados arquitectónicos, entre otros. Cada una de estas piezas artesanales mantiene variedad de contextos culturales y a pesar de ser de difícil producción por la obtención de materia prima, las pocas familias que mantienen este legado, velan por revivir esta actividad dentro de la provincia y el país.
Síndrome de Turner y su impacto sociosanitario en las mujeres de la Fundación Ecuatoriana para la Ayuda del Síndrome de Turner
Authors: Linzán Cedeño Briggitte Sharat , Toala Barahona Félix Fernando
Published: October 2024

El Síndrome de Turner, una afección genética catalogada como huérfana o rara, afecta exclusivamente
a mujeres y se caracteriza por la ausencia total o parcial del cromosoma X. En Ecuador, no existen cifras
específicas que detallen la prevalencia de esta condición; sin embargo, la ciudad de Quito alberga la
Fundación Ecuatoriana Para la Ayuda del Síndrome de Turner, la cual brinda apoyo a mujeres diagnosticadas
con este síndrome. Su base de datos actualmente refleja la participación de 178 mujeres como socias.
Esta condición genera un impacto significativo en los ámbitos social, emocional y de salud de las mujeres
afectadas. En este contexto, el presente artículo tiene como objetivo general analizar el Síndrome de
Turner y su impacto sociosanitario en las mujeres pertenecientes a FEPAST, ubicada en la provincia de
Manabí. Para llevar a cabo este análisis, se adoptó un enfoque cualitativo con un diseño fenomenológico.
Se aplicó una entrevista a profundidad basada en un trabajo previo de operativización de variables de
investigación, el cual fue validado por un grupo de expertos antes de su ejecución. La entrevista se dirigió
a siete socias de la Fundación que residen en la provincia de Manabí, con el propósito de comprender
las experiencias, percepciones y desafíos que enfrentan las mujeres con esta condición genética. Los
resultados obtenidos revelaron aspectos importantes sobre la vivencia del síndrome y su relación con el
entorno sociosanitario.
Futher Operations on Neutrosophic Hypersoft Matrices and Application in Decision Making
Authors: Jayasudha J. , Raghavi S.
Published: October 2024

The main objective of this paper is to extend the concept of Neutrosophic Hypersoft Matrix theory. Neutrosophic soft matrix parametrically evaluates the attributes chosen whereas Neutrosophic hypersoft matrix can parametrically evaluate the sub-attributes of the attributes chosen. Some notions and operations related to Neutrosophic Hypersoft matrices (NHSMs) such as Row-NHSM, Column-NHSM, Diagonal-NHSM, Proper-NHS submatrix, Disjoint NHSM, Extended union (NHSM), Extended intersection (NHSM), addition, subtraction, AND-product and OR-product on NHSM have been introduced with examples. Further a new NHSM-algorithm has been developed based on value matrix, grace matrix and mean matrix to solve Neutrosophic Hypersoft Set based decision-making problems.
Conservative management of an incarcerated uterus in a pregnant woman
Authors: Ngo Mary Le , Westergaard Hanne Brix , Schmiegelow Christentze
Published: October 2024

Incarceration of a retroverted uterus is a rare, but harmful obstetric complication increasing foetal mortality and maternal morbidity if untreated. In this case report, a pregnant woman at 16+3 presented with urine retention. Assessment showed an incarcerated uterus due to retroversion. To facilitate mobilisation of the uterus, she performed the yoga position Downward facing dog and had a permanent catheter inserted for 48 hours. The procedure was successful. This case report addresses the diagnosis, management, and risk of an incarcerated retroverted uterus in pregnancy. We aim to raise awareness, facilitate early diagnosis, and promote the conservative treatment.
Unwarranted cave for opioids
Authors: Uhrbrand Peter Gaarsdal , Skov Kenneth , Eiset Andreas Halgreen , Sædder Eva Aggerholm , Garvey Lene Heise
Published: October 2024

Allergy warnings against opioids are often registered in patient notes which may limit options for pain management. IgE-mediated allergic reactions and anaphylaxis to opioids are infrequent. More frequently, morphine and other opioids cause non-IgE-mediated histamine release leading to milder symptoms which may partly mimic an anaphylactic reaction and cause clinicians to treat it as such. This case report describes a 28-year-old female whose mild reactions were repeatedly misinterpreted as severe allergic reactions, leading to incorrect allergy labels and surgery delay.
Peritonsillar abscess in a nine-week-old patient
Authors: Rangen Jens Kramer , Madsen Magnus Sandberg , Kjærsgaard Søren
Published: October 2024

In this case report, a nine-week-old girl was referred to the ear-, nose- and throat department because of decreased oral intake, swelling of the left tonsil and the left side of the neck. An MRI was performed due to the atypical presentation, which revealed a massive peritonsillar abscess communicating with the swelling on the neck. Treatment consisted of an incision, drainage and intravenous antibiotics. Re-dilation and rinsing were performed on the first post-operative day before extubation. Finally, the patient was discharged after two days with oral antibiotics.
Aortic valve replacement in younger patients with aortic valve insuffienciency
Authors: Jeppesen Tanita Drejer , Hasbak Markus , Hasenkam J. Michael , Benhassen Leila Louise
Published: October 2024

Aortic valve replacement is the common treatment of choice for severe aortic valve insufficiency (AI). AI is often caused by aortic root dilatation which leads to valve incompetence despite structurally normal valve leaflets. For this condition, aortic repair surgery with ring annuloplasty is considered a potentially superior option. Despite the availability of different annuloplasty rings, no guidelines for the surgical procedure nor the choice of annuloplasty ring exist. In this review, we outline the surgical treatment using valve-preserving procedures as an alternative to conventional aortic valve replacement.
Explorando a diversidade da sexualidade na maturidade: um olhar multifacetado
Authors: Borges Pereira Silvanis dos Reis , Da Conceição de Oliveira Carvalho Nogueira Maria , Barbosa Osório Neila
Published: October 2024

A velhice transcende meros números. Ela é um processo dinâmico que engloba não apenas mudanças biológicas, mas também aspectos sociais, psicológicos e de saúde. A conexão entre envelhecimento e sexualidade é uma questão complexa e multifacetada. A sexualidade é uma dimensão intrínseca da experiência humana, desafiando estereótipos e passando por mudanças ao longo das diferentes fases da vida. Com essa concepção, neste artigo, apresenta-se parte de uma pesquisa de doutorado, que tem como objetivo: compreender a representação dos idosos da Universidade da Maturidade do Tocantins sobre as vivências sexuais na maturidade e a relação direta da sexualidade com o bem-estar e coma satisfação com a vida. É pesquisa bibliográfica, de abordagem qualitativa, e quanto ao objetivo descritiva, tem-se por objetivo principal apresentar uma discussão sobre a sexualidade a expressão sexual em indivíduos na fase madura da vida. Conclui-se que a sexualidade deve ser compreendida como um componente essencial para o ser humano, além da simples ideia de atividade sexual e idade. A sexualidade humana é extremamente complexa, não se limitando apenas à atividade física. Ressalta-se a importância do afeto, da intimidade emocional e da conexão pessoal, destacando seus papéis essenciais na experiência sexual e no bem-estar geral das pessoas idosas.
Calculation Ultimate Strength on Media Use Backing Ceramic Against ASTM A36 Steel by SMAW Process
Authors: Rahman Sabaruddin
Published: October 2024

Metal welding of large structures often requires alternating welding on both sides, which can be costly and time-consuming. However, welding results are only sometimes perfect, and gaps often require solutions to maximize welding results. One solution is using media backing ceramic as a support that can give better results. This study aims to evaluate the effect of backing ceramic and non-backing ceramics on the strength of the tensile test results on ASTM A36 steel using SMAW welding. The results of the tensile test show that there is an effect of strength on ASTM A36 steel. Mark Ultimate Tensile Strength, the highest, was obtained on specimens that did not use backing ceramics, equal to 451.893 Mpa. In contrast, the lowest value of Ultimate Tensile Strength was obtained on the specimen using backing ceramics, equal to 428.736 MPa.
Relationship of Occupational Accidents to K3 Knowledge, K3 Training, and Use of Personal Protective Equipment in the Welding Process
Authors: Bin Yusup Muhammad Firdaus
Published: October 2024

The rapid development of science and technology provides convenience in the industrial world, such as increasing work productivity and the number of workers. However, the development of technology has problems, one of which is the problem of occupational safety and health which can cause harm to workers and companies. Often, welders neglect personal protective equipment, which can result in work accidents when welding. Therefore, this research was conducted to determine the relationship between occupational accidents and OSH knowledge, OSH training, and the use of personal protective equipment in the welding process. The method used is univariate and bivariate analysis. The results showed a significant relationship between K3 knowledge and occupational accidents in the welding process (sig. 0.001 <0.005). At the same time, there was no significant relationship between K3 training (sig. 0.235 value > 0.005) and the use of PPE (sig. 0.187 > 0.005) with work accidents in the welding process.
Welding Training Flux Cored Arc Welding (FCAW) in Improving Welding Skills
Authors: Husain Firman
Published: October 2024

The connection method using welding has advantages compared to other methods, including better connection efficiency, can be used in constructions that work at high temperatures, and the results are neater. The connection resulting from the welding process is permanent, and the process is faster. However, the quality of welding results is strongly influenced by the skill and ability to weld welder. Therefore, welding training is very important to improve skills, so welding training is held for the community in Laok Jang-Jang Village, Arjasa District, Sumenep Regency, East Java Province. This training includes providing material on Occupational Health Safety (K3), basic FCAW welding, and welding practices. The training results showed an increase in the skills of the trainees, as seen from the welding results, which had no defects. This shows that the trainees have applied the material provided before carrying out Flux Cored Arc Welding (FCAW) welding processes.
THE UNSTOPPABLE PANTELIMON 2024 TRIATHLON FROM THE PERSPECTIVE OF THE PARTICIPANTS
Authors:   University of Bucharest, 90, Panduri Street, Sector 5, 050663, Bucharest, Romania, ŞERBAN Cătălin , GOZU Bogdan ,   University of Bucharest, 90, Panduri Street, Sector 5, 050663, Bucharest, Romania
Published: October 2024

As a result of an increasingly important need to compensate for the harmful effects of the lack of movement determined by daily activities, people are looking for more and more diverse and challenging alternatives in the area of free time motor activities, so that the benefits cover both the physical and the mental sphere as well. By nature and their particularities, triathlon competitions, in general, fit very well into this category, gaining more and more ground compared to other forms of movement, in the options of the participants, precisely because they offer a favorable environment where everyone can test their limits, can compete with other people and establish his own training strategy.Having this important and interesting information at hand, we will be able to better understand the perspective, preferences and reporting of the participants to the particularities of such a competition, all in the context of a deep awareness of the importance of constant involvement in a form of movement. The main purpose of this research is to create a profile of the participant in the Unstoppable Pantelimon 2024 Triathlon, by applying a questionnaire designed to lead to the identification of the main reasons that were the basis of this option. Moreover, through our scientific approach, we aim to highlight the way in which this competition resonates with the expectations and preparation strategies of the participants, thus leading to a common perspective regarding the benefits of participating in these physical activities.
EVOLUTION OF THE GAME OF FOOTBALL IN TERMS OF RULES AND FORMATIONS OF PLAY
Authors:   Universitatea Națională de Educație Fizică și Sport, Str. Constantin Noica, Nr. 140, Sector 6, C.P. 060057, Bucureşti, România, VICOL Sebastian-Iulian , TEODORESCU Silvia ,   Universitatea Națională de Educație Fizică și Sport, Str. Constantin Noica, Nr. 140, Sector 6, C.P. 060057, Bucureşti, România, DUMITRU Nicoleta ,   Universitatea din București, Ștr. Edgar Quinet, Nr. 5-7, Sector 1, C.P. 010017, București, România
Published: October 2024

The game of football has, throughout its history, provided moments of unparalleled spectacle and popularity, with a global following. From the earliest documented instances of ball games played with the feet, without clearly defined rules, to the most sophisticated styles of play observed in modern times, the evolution of football has been a continuous process. The development of football has been influenced by the contributions of renowned coaches and players who have introduced innovative techniques, such as "tiki-taka" and the "Galacticos." These innovations have shaped the evolution of the sport in response to the demands of the modern era. A number of renowned coaches, including Helenio Herrera, Sir Alex Ferguson, Rinus Michels, Enzo Bearzot, Johan Cruyff, Pep Guardiola and others, have employed creativity to devise innovative systems of play and principles to enhance the abilities of their players, with the objective of achieving victories. The objective of this study was to analyse the literature on the subject and illustrate the game systems that were employed in the earliest official matches and how they evolved in response to changes in the regulations. Over time, international governing bodies have issued regulations that have compelled coaches to be creative and identify optimal strategies for their teams to achieve victory and perform at their best. Each system of play has been described in chronological order, with the aim of establishing a correlation between the rules of play and the systems employed at the time. The field of football is undergoing continuous development, with technology playing an increasingly significant role in the conduct of matches. Software and statistical data are being used by referees and coaches to inform decision-making, thereby reducing the time required for decision-making.
BOOSTING STUDENT ENGAGEMENT IN UNIVERSITY PHYSICAL ACTIVITIES: AN EXPLORATORY STUDY
Authors:   Faculty of Psychology – Psychology and Cognitive Sciences II, BURCIU Daniela , STOICA Alina-Mihaela ,   Department of Physical Education and Sport University of Bucharest, Romania
Published: October 2024

Physical activity is a critical component of a healthy lifestyle, significantly contributing to the prevention and management of chronic diseases, mental health support, and overall well-being. Despite its benefits, recent lifestyle changes in post-communist Romania have led to an alarming increase in overweight and obesity rates, especially among urban youth. This research focuses on the University of Bucharest (UniBuc) to explore the reasons behind students' low participation in university-organized physical activities. By employing a structured questionnaire distributed electronically, this study aims to collect comprehensive data on student demographics, participation levels, motivations, barriers, and suggestions for improvement. The quantitative analysis component of the study aims to identify participation trends and barriers, while qualitative insights will provide nuanced perspectives on students' experiences. The findings will inform targeted strategies to promote physical activity among students, contributing to their immediate and long-term health. Overall, this exploratory study seeks to lay the groundwork for future research on enhancing physical activity participation in academic settings, ultimately supporting the holistic development of young adults.
Analisis Sistem Akuntansi Pemberian Kredit Pemilikan Rumah (KPR) pada PT Bank Central Asia Tbk Cabang Pettarani Makassar
Authors: Gafur Abd , Syah Sri Rahayu , Julkifli Julkifli , Irmawati Ika
Published: October 2024

This study aims to understand the home ownership credit accounting system at PT Bank Central Asia Tbk Pettarani Makassar Branch, with a focus on simple requirements and a fast credit application process.
Based on research conducted at PT Bank Central Asia Tbk Pettarani Makassar Branch, the use of the MyCore application in providing home ownership credit can facilitate the input of prospective debtor files in an effective and efficient manner, thereby speeding up the process. The author applies a qualitative research method, which produces descriptive data in the form of written notes and oral information from individuals observed during data collection in the field.
The results of the study show that the process of applying for a home ownership loan at PT Bank Central Asia Tbk Pettarani Makassar Branch has become easier and faster because the requirements applied are general requirements that are already owned by customers. This allows the collection of files to be done more quickly.
Can highly nutritious semi-processed products help reduce food waste in Kenya?
Authors:   Busara, Kiarie Wanjiku , Koki Edel , Kuria Nengapate , Mogere Daniel , Murithi Mugambi , Muthiki Wairimu , Nyaga Robert , Oberoi Zeena , Wambua Ruth
Published: October 2024

Understanding consumer behaviors and habits to ensure low -income consumers have improved access to safe, affordable and nutritious fruits and vegetables in Kenya. The UNEP Food Waste Index Report 2021, indicated that every Kenyan throws away an average of 99 kilograms of food every year, with the country wasting a total of 5.2 tonnes of food every 12 months. Most of this food loss happens post harvest when there is oversupply as well as due to preference of high visually appealing produce. TechnoServe, through the NutriSave project, aims to reduce food loss by increasing consumption of highly nutritious semi-processed products specifically focusing on mango juice, tomato paste, and porridge fortified with african leafy vegetables, which would increase demand for low visually appealing vegetables. The project targets low-income consumers in urban and peri-urban areas in Nairobi.
Self-sustaining energy as an alternative to power outages in the Pueblo Unido sector in 2024
Authors: Montero Reyes Yilena , Villacis Anthony , Garces Yandri , Loachamin Roberth
Published: October 2024

Introduction: power outages are a common problem in many parts of the world due to various reasons, it is important to consider self-sustaining energy as a viable alternative.Objective: to determine the knowledge in the Pueblo Unido sector about self-sustaining energy as an alternative to power outages.Method: an observational, descriptive, and cross-sectional study was conducted to assess knowledge related to self-sustaining energy as an alternative to power outages in the Pueblo Unido sector in 2024.Results: 52.1 % are female, 43.8 % have power outages every month, 60.4 % usually have power outages for one hour, 52.1 % have problems with delays in household and work activities during the year, 54.2 % have ever considered installing self-sustaining energy systems, 87.5 % believe that the implementation of self-sustaining energy could reduce the frequency of power outages.Conclusions: the potential of self-sustaining energy systems based on motor and bicycle generators to address the challenges related to power outages is highlighted, while promoting sustainability, resilience, and community well-being
Factors Influencing Academic Performance: An Empirical Study Using Predictive Analytics
Authors: Islam Farheen , Krishna Aprajita , Kumar Devanshu , Kumari Sangeeta
Published: October 2024

Introduction: Student academic performance is commonly measured using indicators like credit scores, class rankings, or passing thresholds, each offering insight into a student’s comprehension and progress. These measures give a numeric evaluation of a student's understanding of the course content, enabling educators and institutions to monitor growth over time. Moreover, the capacity to forecast academic performance proves highly beneficial for both students and teachers, as it enables early interventions and course corrections. This predictive ability can lead to tailored learning strategies, ultimately enhancing educational outcomes and supporting overall student success.Method: To carry out a statistical analysis on the dataset (kaggel), the first step will involve cleaning and preprocessing the data to address any missing or non-numeric entries. Once the dataset is refined, hypothesis testing and ANOVA will be employed to pinpoint the key factors that influence student performance. Result: Initial findings suggest that study hours and attendance are significant predictors of exam scores, with higher values generally leading to better performance. Additionally, motivational factors, parental involvement, and access to academic resources showed varying degrees of influence, highlighting their potential role in shaping educational outcomes. Conclusion: Through descriptive statistics, correlation analysis, and regression models, the dataset offers insights that can be used by educators and policymakers to enhance teaching strategies and student support systems. By identifying key factors that affect student outcomes, the dataset provides a foundation for future research and practical interventions aimed at improving academic performance in educational settings