bluuebunny/crossref_metadata_2025 huggingface dataset:
Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models
Authors: Dingledine Raymond , Coulter Douglas A. , Fritsch Brita , Gorter Jan A. , Lelutiu Nadia , McNamara James , Nadler J. Victor , Pitkänen Asla , Rogawski Michael A. , Skene Pate , Sloviter Robert S. , Wang Yu , Wadman Wytse J. , Wasterlain Claude , Roopra Avtar
Published: May 2017

Global expression profiling of neurologic or psychiatric disorders has been confounded by variability among laboratories, animal models, tissues sampled, and experimental platforms, with the result being that few genes demonstrate consistent expression changes. We attempted to minimize these confounds by pooling dentate granule cell transcriptional profiles from 164 rats in seven laboratories, using three status epilepticus (SE) epilepsy models (pilocarpine, kainate, self-sustained SE), plus amygdala kindling. In each epilepsy model, RNA was harvested from laser-captured dentate granule cells from six rats at four time points early in the process of developing epilepsy, and data were collected from two independent laboratories in each rodent model except SSSE. Hierarchical clustering of differentially-expressed transcripts in the three SE models revealed complete separation between controls and SE rats isolated 1 day after SE. However, concordance of gene expression changes in the SE models was only 26–38% between laboratories, and 4.5% among models, validating the consortium approach. Transcripts with unusually highly variable control expression across laboratories provide a ‘red herring’ list for low-powered studies.
Serum glycopattern and Maackia amurensis lectin-II binding glycoproteins in autism spectrum disorder
Authors: Qin Yannan , Chen Yanni , Yang Juan , Wu Fei , Zhao Lingyu , Yang Fuquan , Xue Peng , Shi Zhuoyue , Song Tusheng , Huang Chen
Published: May 2017

The pathophysiology of autistic spectrum disorder (ASD) is not fully understood and there are no diagnostic or predictive biomarkers. Glycosylation modified as many as 70% of all human proteins can sensitively reflect various pathological changes. However, little is known about the alterations of glycosylation and glycoproteins in ASD. In this study, serum glycopattern and the maackia amurensis lectin-II binding glycoproteins (MBGs) in 65 children with ASD and 65 age-matched typically developing (TD) children were compared by using lectin microarrays and lectin-magnetic particle conjugate-assisted LC-MS/MS analyses. Expression of Siaα2-3 Gal/GalNAc was significantly increased in pooled (fold change = 3.33, p < 0.001) and individual (p = 0.009) serum samples from ASD versus TD children. A total of 194 and 217 MGBs were identified from TD and ASD sera respectively, of which 74 proteins were specially identified or up-regulated in ASD. Bioinformatic analysis revealed abnormal complement cascade and aberrant regulation of response-to-stimulus that might be novel makers or markers for ASD. Moreover, increase of APOD α2-3 sialoglycosylation could sensitively and specifically distinguish ASD samples from TD samples (AUC is 0.88). In conclusion, alteration of MBGs expression and their sialoglycosylation may serve as potential biomarkers for diagnosis of ASD, and provide useful information for investigations into the pathogenesis of ASD.
A Novel Sensitive Luminescence Probe Microspheres for Rapid and Efficient Detection of τ-Fluvalinate in Taihu Lake
Authors: Wang Jixiang , Wang Yunyun , Qiu Hao , Sun Lin , Dai Xiaohui , Pan Jianming , Yan Yongsheng
Published: May 2017

Fluorescent molecularly imprinted polymers have shown great promise in biological or chemical separations and detection, due to their high stability, selectivity and sensitivity. In this work, fluorescent molecularly imprinted microsphere was synthesized via precipitation polymerization, which could separate efficiently and rapidly detect τ-fluvalinate (a toxic insecticide) in water samples, was reported. The fluorescent imprinted sensor showed excellent stability, outstanding selectivity and the limit of detection low to 12.14 nM, good regeneration ability which still kept good sensitivity after 8 cycling experiments and fluorescence quenching mechanism was illustrated in details. In addition, the fluorescent sensor was further used to detect τ-fluvalinate in real samples from Taihu Lake. Despite the relatively complex components of the environment water, the fluorescent imprinted microspheres sitll showed good recovery, clearly demonstrating the potental value of this smart sensor nanomaterial in environment monitoring.
Correction: Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation
Authors: Phelps Edward A. , Cianciaruso Chiara , Santo-Domingo Jaime , Pasquier Miriella , Galliverti Gabriele , Piemonti Lorenzo , Berishvili Ekaterine , Burri Olivier , Wiederkehr Andreas , Hubbell Jeffrey A. , Baekkeskov Steinunn
Published: May 2017

Scientific Reports 7: Article number: 45961; published online: 12 April 2017; updated: 09 May 2017 This Article contains a typographical error in the Methods section under subheading ‘Data Availability. Associated Article’, “Protocol Exchange doi: 1038/Protex.2017.039 (2017)”. should read: “ProtocolExchange doi: 10.
Correction: Corrigendum: miR302 regulates SNAI1 expression to control mesangial cell plasticity
Authors: De Chiara Letizia , Andrews Darrell , Watson Ariane , Oliviero Giorgio , Cagney Gerard , Crean John
Published: May 2017

Scientific Reports 7: Article number: 42407; published online: 14 February 2017; updated: 09 May 2017 The original version of this Article contained errors in the spelling of the authors Letizia De Chiara, Darrell Andrews, Ariane Watson, Giorgio Oliviero, Gerard Cagney and John Crean which were incorrectly given as L.
Adenosine A2A receptor inactivation alleviates early-onset cognitive dysfunction after traumatic brain injury involving an inhibition of tau hyperphosphorylation
Authors: Zhao Z-A , Zhao Y , Ning Y-L , Yang N , Peng Y , Li P , Chen X-Y , Liu D , Wang H , Chen X , Bai W , Chen J-F , Zhou Y-G
Published: May 2017

Tau is a microtubule-associated protein, and the oligomeric and hyperphosphorylated forms of tau are increased significantly after neurotrauma and considered important factors in mediating cognitive dysfunction. Blockade of adenosine A2A receptors, either by caffeine or gene knockout (KO), alleviates cognitive dysfunction after traumatic brain injury (TBI). We postulated that A2AR activation exacerbates cognitive impairment via promoting tau hyperphosphorylation. Using a mouse model of moderate controlled cortical impact, we showed that TBI induced hyperphosphorylated tau (p-tau) in the hippocampal dentate gyrus and spatial memory deficiency in the Morris water maze test at 7 days and 4 weeks after TBI. Importantly, pharmacological blockade (A2AR antagonist ZM241385 or non-selective adenosine receptor antagonist caffeine) or genetic inactivation of A2ARs reduced the level of tau phosphorylation at Ser404 and alleviated spatial memory dysfunction. The A2AR control of p-tau is further supported by the observations that a KO of A2AR decreased the activity of the tau phosphorylation kinases, glycogen synthase kinase-3β (GSK-3β) and protein kinase A (PKA) after TBI, and by that CGS21680 (A2AR agonist) exacerbated okadaic acid-induced tau hyperphosphorylation in cultured primary hippocampal neurons. Lastly, CGS21680-induced neuronal tau hyperphosphorylation and axonal injury were effectively alleviated by individual treatments with ZM241385 (A2AR antagonist), H89 (PKA antagonist) and SB216763 (GSK-3β antagonist), or by the combined treatment with H89 and SB216763. Our findings suggest a novel mechanism whereby A2AR activation triggers cognitive dysfunction by increasing the phosphorylation level of tau protein after TBI and suggest a promising therapeutic and prophylactic strategy by targeting aberrant A2AR signaling via tau phosphorylation.
Solubility limits in quaternary SnTe-based alloys
Authors: Siol Sebastian , Holder Aaron , Ortiz Brenden R. , Parilla Philip A. , Toberer Eric , Lany Stephan , Zakutayev Andriy
Published: May 2017

A combined theoretical and experimental approach was used to determine the equilibrium as well as non-equilibrium solubility lines in the quaternary Sn1−yMnyTe1−xSex alloy space, revealing a large area of accessible metastable phase space.
An arylboronate locked fluorescent probe for hypochlorite
Authors: Shi Leilei , Li Xin , Zhou Min , Muhammad Faheem , Ding Yubin , Wei Hui
Published: May 2017

An unusual arylboronate based fluorescent probeR1was synthesized for the selective and sensitive detection of ClO−.
Ultrasensitive fluorescence detection of transcription factors based on kisscomplex formation and the T7 RNA polymerase amplification method
Authors: Zhang Kai , Wang Ke , Zhu Xue , Xie Minhao
Published: May 2017

Herein, we report a kisscomplex based protein fluorescence assay (KPFA) method, which employed the formation of a kisscomplex and the T7 RNA polymerase amplification method, for the assay of transcription factors with high sensitivity. The detection limits of MITF and NF-κB p65 are 0.23 pM and 0.496 pM, respectively.
3D and 2D supramolecular assemblies and thermotropic behaviour of a carbo-benzenic mesogen
Authors: Zhu Chongwei , Wang Tsai-Hui , Su Chien-Jhang , Lee Shern-Long , Rives Arnaud , Duhayon Carine , Kauffmann Brice , Maraval Valérie , Chen Chun-hsien , Hsu Hsiu-Fu , Chauvin Remi
Published: May 2017

A carbo-benzenic mesogen gives rise to a tubular-columnar discotic liquid crystal at 115 °C, the rectangular arrangement of which is identical in STM images on an HOPG surface.
IF5 affects the final stage of the Cl–F exchange fluorination in the synthesis of pentafluoro-λ6-sulfanyl-pyridines, pyrimidines and benzenes with electron-withdrawing substituents
Authors: Cui Benqiang , Kosobokov Mikhail , Matsuzaki Kohei , Tokunaga Etsuko , Shibata Norio
Published: May 2017

SF5-(hetero)arenes having electron-deficient groups were efficiently synthesized by oxidative chlorotetrafluorination followed by a SNi-type Cl–F exchange reaction using IF5.
Near infrared two photon imaging using a bright cationic Yb(iii) bioprobe spontaneously internalized into live cells
Authors: Bui Anh Thy , Beyler Maryline , Grichine Alexei , Duperray Alain , Mulatier Jean-Christophe , Guyot Yannick , Andraud Chantal , Tripier Raphaël , Brasselet Sophie , Maury Olivier
Published: May 2017

An Yb(iii) complex based on a dimethyl cyclen macrocyclic ligand is used as two-photon NIR bioprobe.
Low-temperature-selective luminescent mechanochromism of a thienyl gold isocyanide complex
Authors: Seki Tomohiro , Kobayashi Koh , Ito Hajime
Published: May 2017

The low-temperature-selective mechanochromism of a thienyl gold(i) isocyanide complex is reported.
3T1R model and tuning of thermoluminescence intensity by optimization of dopant concentration in monoclinic Gd2O3:Er3+;Yb3+ co-doped phosphor
Authors: Tamrakar Raunak Kumar , Upadhyay Kanchan , Bisen D. P.
Published: May 2017

Thermoluminescence property of a phosphor is an important parameter that helps to determine the use of a phosphor in various dosimetric applications.
Ion-induced molecular growth in clusters of small hydrocarbon chains
Authors: Gatchell Michael , Delaunay Rudy , D'Angelo Giovanna , Mika Arkadiusz , Kulyk Kostiantyn , Domaracka Alicja , Rousseau Patrick , Zettergren Henning , Huber Bernd A. , Cederquist Henrik
Published: May 2017

We report on studies of collisions between 3 keV Ar+ projectile ions and neutral targets of isolated 1,3-butadiene (C4H6) molecules and cold, loosely bound clusters of these molecules.
Naphthodifuran-based zigzag-type polycyclic arene with conjugated side chains for efficient photovoltaics
Authors: Peng Hongjian , Luan Xiangfeng , Feng Liuliu , Yuan Jun , Zhang Zhi-Guo , Li Yongfang , Zou Yingping
Published: May 2017

Two alkoxyphenyl-substituted naphthodifuran (zNDF)-based polymers (PzNDFP-BT and PzNDFP-ffQx) were synthesized. A promising PCE of 6.9% has been obtained, which is the highest PCE among zNDF-based polymers to date.
Electrochemical evaluation methods of vanadium flow battery electrodes
Authors: Wu Lantao , Wang Jianshe , Shen Yi , Liu Le , Xi Jingyu
Published: May 2017

A reliable device as well as parameters is important for the electrochemical evaluation of a VFB electrode to achieve more convincing results.
Geometric effect in the highly selective hydrogenation of 3-methylcrotonaldehyde over Pt@ZIF-8 core–shell catalysts
Authors: Lan Xiaocheng , Huang Ning , Wang Jinfu , Wang Tiefeng
Published: May 2017

The geometric effect of the Pt@ZIF-8 catalyst was investigated for the highly selective hydrogenation of 3-methylcrotonaldehyde to unsaturated alcohols.
Bifunctional property of Pt nanoparticles deposited on TiO2 for the photocatalytic sp3C–sp3C cross-coupling reactions between THF and alkanes
Authors: Tyagi Akanksha , Yamamoto Akira , Kato Tatsuhisa , Yoshida Hisao
Published: May 2017

Photocatalytic direct cross-coupling between THF and alkanes was accelerated by Pt nanoparticles on TiO2, as a receiver for photoexcited electron and a metal catalyst.
Au38Cu1(2-PET)24 nanocluster: synthesis, enantioseparation and luminescence
Authors: Kazan Rania , Zhang Bei , Bürgi Thomas
Published: May 2017

Two different species of the chiral Au38Cu1(2-PET)24 adduct, showing enhanced fluorescence, were successfully separated using chiral HPLC.
A dual-emission probe to detect moisture and water in organic solvents based on green-Tb3+ post-coordinated metal–organic frameworks with red carbon dots
Authors: Wu Jing-Xing , Yan Bing
Published: May 2017

A new dual-emission Tb3+@p-CDs/MOF (red carbon dots, green Tb3+) serves as a luminescent sensor for water and humidity, due to the agglomeration effect of p-CDs in different solvents.
Graphitic carbon nitride-based nanocomposites as visible-light driven photocatalysts for environmental purification
Authors: Ding Fei , Yang Dong , Tong Zhenwei , Nan Yanhu , Wang Yujie , Zou Xiaoyan , Jiang Zhongyi
Published: May 2017

This review presents an overview about graphitic carbon nitride-based nanocomposites as visible-light driven photocatalysts for environmentally relevant applications.
Effects of natural minerals on the adsorption of 17β-estradiol and bisphenol A on graphene oxide and reduced graphene oxide
Authors: Sun Weiling , Wang Conghe , Pan Weiyi , Li Si , Chen Ben
Published: May 2017

Natural minerals affect the adsorption of 17β-estradiol and bisphenol A on GO and rGO.
Improved contaminant removal in vegetated stormwater biofilters amended with biochar
Authors: Ulrich Bridget A. , Loehnert Megan , Higgins Christopher P.
Published: May 2017

The potential for carbonaceous sorbents to improve contaminant removal (particularly for trace organic contaminants, TOrCs) in stormwater biofilters was evaluated in intermittently dosed, vegetated columns simulating scaled-down treatment systems.
What can be inferred from moiré patterns? A case study of trimesic acid monolayers on graphite
Authors: Spitzer Saskia , Helmle Oliver , Ochs Oliver , Horsley Joshua , Martsinovich Natalia , Heckl Wolfgang M. , Lackinger Markus
Published: May 2017

Self-assembly of benzene-1,3,5-tricarboxylic acid (trimesic acid – TMA) monolayers at the alkanoic acid–graphite interface is revisited. Even though this archetypal model system for hydrogen bonded porous networks is particularly well studied, the analysis of routinely observed superperiodic contrast modulations known as moiré patterns lags significantly behind. Fundamental questions remain unanswered such as, are moiré periodicity and orientation always the same, i.e. is exclusively only one specific moiré pattern observed? What are the geometric relationships (superstructure matrices) between moiré, TMA, and graphite lattices? What affects the moiré pattern formation? Is there any influence from solvent, concentration, or thermal treatment? These basic questions are addressed via scanning tunneling microscopy experiments at the liquid–solid interface, revealing a variety of different moiré patterns. Interestingly, TMA and graphite lattices were always found to be ∼5° rotated with respect to each other. Consequently, the observed variation in the moiré patterns is attributed to minute deviations (<2°) from this preferred orientation. Quantitative analysis of moiré periods and orientations facilitates the determination of the TMA lattice parameter with picometer precision.
Further expanding versatility of surface-enhanced Raman spectroscopy: from non-traditional SERS-active to SERS-inactive substrates and single shell-isolated nanoparticle
Authors: Ding Song-Yuan , You En-Ming , Yi Jun , Li Jian-Feng , Tian Zhong-Qun
Published: May 2017

After surface-enhanced Raman spectroscopy (SERS) was initiated over four decades ago, its practical application seems to be far behind the fundamental research that has made tremendous progress. SERS as a highly sensitive technique has not been widely adopted by the materials science and surface science communities or in the market of analytical instruments. In this discussion, we first classify the previous approaches along this direction over the past four decades and divide them into three strategies. Based on our recent theoretical and experimental approaches, we discuss in more detail the third strategy related to shell-isolated nanostructures. It can significantly expand the SERS study on nontraditional SERS-active (i.e. weakly SERS-active) materials (e.g. Pt, Ni, Fe, etc.) and even SERS-inactive materials (e.g. Si and Al2O3). We then focus on a single shell-isolated nanoparticle and how to controllably locate the strong electromagnetic field just at the probe surface of various materials. The use of side illumination at a high incident angle and/or nanocubes can further enhance the Raman signal by one to two orders of magnitude, which could be helpful for quantitative studies for surface science, heterogeneous catalysis, and soft matter science.
Plasmon induced polymerization using a TERS approach: a platform for nanostructured 2D/1D material production
Authors: Zhang Zhenglong , Richard-Lacroix Marie , Deckert Volker
Published: May 2017

Plasmon-induced chemical reactions have recently attracted great attention as a promising method for high efficiency light-energy conversion and proved to be useful in a wealth of different domains of chemistry and physics. One of the interesting and, so far, less explored avenues of such reactions is their potential for efficient, highly localized and controlled polymer production. Here, we present the first example of a localized, directed plasmon catalyzed polymerization process of a self-assembled monolayer on both silver and gold surfaces monitored by surface- and tip-enhanced Raman spectroscopy (SERS and TERS). As a proof-of-concept, a bi-functionalized dibenzo(1,2)dithiine-3,8-diamine (D3ATP) molecule that undergoes a well-known plasmon-induced coupling via the amino group into an azo group has been used. Initial dimerization is demonstrated using established marker bands associated with the formation of the azo group. A subsequent indicator for a polymerization reaction, the appearance of a new characteristic band, is monitored by time-dependent SERS and TERS experiments. We demonstrate that the dimerization reaction and hence, the subsequent polymerization, can be induced by a plasmonic feature, e.g. a TERS tip, at specific nanoscale locations and, at a much larger micron scale, by continuously scanning the plasmonic probe. The presented results provide the basis for designing further plasmonic catalysis experiments in general, and offer a new platform for producing ultra-thin polymer films with a defined structural dimension.
Direct conversion of γ,γ-dicarbonyl-substituted aldehydes into γ-lactones with a sodium chlorite/DBDMH combination
Authors: Guo Yanjun , Xia Aibao , Meng Chenhong , Xu Zhenyuan , Xu Danqian
Published: May 2017

An unprecedented and challenging simultaneous carboxylation/halogenation, and next lactonization of γ,γ-dicarbonyl-substituted aldehydes has been realized using a NaClO2/DBDMH combination.
Femtosecond laser ablation inductively coupled plasma source mass spectrometry for elemental and isotopic analysis: are ultrafast lasers worthwhile?
Authors: Poitrasson Franck , d'Abzac François-Xavier
Published: May 2017

The figures of merit of fs laser ablation for LA-ICP-MS analysis are reviewed.
Characterization of extreme ultraviolet laser ablation mass spectrometry for actinide trace analysis and nanoscale isotopic imaging
Authors: Green Tyler , Kuznetsov Ilya , Willingham David , Naes Benjamin E. , Eiden Gregory C. , Zhu Zihua , Chao W. , Rocca Jorge J. , Menoni Carmen S. , Duffin Andrew M.
Published: May 2017

We characterize EUV TOF for trace analysis using NIST glasses and demonstrate nanoscale imaging on uranium oxide particles.
Magnetic sensing platform technologies for biomedical applications
Authors: Lin Gungun , Makarov Denys , Schmidt Oliver G.
Published: May 2017

A review highlighting the historical basis, routes and roadmap of the development of magnetic biosensing platform technologies.
Mechanisms of iron and copper–frataxin interactions
Authors: Han T. H. L. , Camadro J. M. , Santos R. , Lesuisse E. , El Hage Chahine J. M. , Ha-Duong N. T.
Published: May 2017

Investigation of the mechanisms of mitochondrial metal binding to frataxinin vitro.
A green direct preparation of a magnetic ordered mesoporous carbon catalyst containing Fe–Pd alloys: application to Suzuki–Miyaura reactions in propane-1,2-diol
Authors: Peter C. , Derible A. , Parmentier J. , Le Drian C. , Becht J.-M.
Published: May 2017

A mesoporous carbon containing Fe–Pd alloys showed excellent activity for Suzuki–Miyaura couplings using tiny amounts of Pd and afforded Pd-free products after reaction.
Impact and correlation of pKaand dnelectrons of some selected thiosemicarbazone Schiff base metal Co, Ni, Cu complexes: a study of electrochemical behavior, excitation and optical energies
Authors: El-Shahawi M. S. , Ahmad W. , Mohammed G. I. , Moustafa Y. M. , Al-Hazmi G. A. , El-Asmy A. A.
Published: May 2017

The electron-transfer and coordination mechanism of thiosemicarbazone Schiff bases with metal ions (Co, Ni, Cu), correlation of the electrochemical and optical properties for their potential applications in various fields of chemistry and biochemistry are underexplored.
The preparation of a porous melamine–formaldehyde adsorbent grafted with polyethyleneimine and its CO2 adsorption behavior
Authors: Yin Fengqin , Peng Peixuan , Mo Wenjie , Chen Shuixia , Xu Teng
Published: May 2017

A porous amino resin with a high content of hydroxymethyl groups was prepared via the polycondensation of an excess of formaldehyde with melamine. PEI was then grafted onto the porous amino resin to synthesize a solid amine adsorbent for CO2 adsorption.
Synthesis and photophysical characterization of bacteriochlorins equipped with integral swallowtail substituents
Authors: Liu Yizhou , Allu Srinivasarao , Nagarjuna Reddy Muthyala , Hood Don , Diers James R. , Bocian David F. , Holten Dewey , Lindsey Jonathan S.
Published: May 2017

The two pyrroline units of bacteriochlorins can now bear gem-dialkyl or diaryl groups (L), which project above and below the macrocycle plane, whereas dimethyl groups generally have been accessible previously.
PEG-600 mediated one-pot reaction of 3-acetyl-2H-chromen-2-one with heterylthiols and phenylthioureas using tetrabutylammonium tribromide as an efficient green reagent
Authors: Srikrishna Devulapally , Kumar Dubey Pramod
Published: May 2017

A simple method for the one-pot reaction of 3-acetyl-2H-chromen-2-one with different heterylthiols and phenylthioureas under green conditions using tetrabutylammonium tribromide (TBATB) as an efficient reagent has been described.
Synthesis, structure and thermolysis of oxazagermines and oxazasilines
Authors: Dannenberg F. , Thiele G. , Dornsiepen E. , Dehnen S. , Mehring M.
Published: May 2017

Nine new oxazasilines and oxazagermines were characterized and two of them were proven to be suitable precursors for porous Ge@C.
Synthesis of new terpyridine-like ligands based on triazolopyridines and benzotriazoles
Authors: Cabrero-Antonino M. , Ballesteros-Garrido R. , Chiassai L. , Escrivà E. , Ramirez de Arellano C. , Ballesteros R. , Abarca B.
Published: May 2017

Herein, terpyridine triazole-based analogs bearing benzotriazoles or/and triazolopyridines are preparedviacopper catalysis, where the arrangement of the nitrogen atoms is proven to be crucial to the spectroscopic properties of these ligands.
A hybrid composite catalyst of Fe3O4 nanoparticles-based carbon for electrochemical reduction of oxygen
Authors: Chen Zongkun , Lin Fei , He Dandan , Jiang Heqing , Zhang Jingjing , Wang Xin , Huang Minghua
Published: May 2017

We report an Fe3O4 nanoparticles-based carbon catalyst with good electrical conductivity, abundant active sites and efficient catalytic ORR activity.
Contact chemosensation of phytochemicals by insect herbivores
Authors: Pentzold Stefan , Burse Antje , Boland Wilhelm
Published: May 2017

Contact chemosensation, or tasting, enables insect herbivores to identify nonvolatile metabolites in complex mixtures present in plants. The interplay of primary and secondary plant metabolites with gustatory receptors is outlined.
Chemical differentiation of three DMSP lyases from the marine Roseobacter group
Authors: Burkhardt Immo , Lauterbach Lukas , Brock Nelson L. , Dickschat Jeroen S.
Published: May 2017

The kinetics of three bacterial DMSP lyases with natural and artificial substrates were studied. Their mechanisms and possible ecological functions are discussed.
Re-characterization of hammerhead ribozymes as molecular tools for intermolecular RNA cleavage
Authors: Liu Getong , Huang Xin , Pu Qinlin , Zhao Yongyun , Du Feng , Dong Juan , Cui Xin , Tang Zhuo
Published: May 2017

A new guideline for the use of hammerhead ribozymes as molecular tools in intermolecular RNA-cleaving.
Gas separation mechanism of CO2 selective amidoxime-poly(1-trimethylsilyl-1-propyne) membranes
Authors: Feng Hongbo , Hong Tao , Mahurin Shannon M. , Vogiatzis Konstantinos D. , Gmernicki Kevin R. , Long Brian K. , Mays Jimmy W. , Sokolov Alexei P. , Kang Nam-Goo , Saito Tomonori
Published: May 2017

Amidoxime functionalization on polymer matrix significantly increases CO2/N2 solubility selectivity.
Photoinduced controlled radical polymerization of methacrylates with benzaldehyde derivatives as organic catalysts
Authors: Ma Wenchao , Zhang Xianhong , Ma Yuhong , Chen Dong , Wang Li , Zhao Changwen , Yang Wantai
Published: May 2017

Under 23 W CFL irradiation, block copolymers are obtained starting from a Pn-I macroinitiator in the presence of a benzaldehydic molecule-based catalytic system.
Anionic polymerization of ethyl acrylate initiated by tetrabutylammonium azide: direct synthesis of end-clickable polyacrylate
Authors: Kataoka Yuki , Kohsaka Yasuhiro , Kitaura Takehiro , Domae Shogo , Ishihara Shoya , Kitayama Tatsuki
Published: May 2017

Tetrabutylammonium azide, a weak nucleophile, was found to initiate the living anionic polymerization of ethyl acrylate in the presence of alkylaluminum bisphenoxides as monomer activators to afford clickable azide-end polymers.
C1 polymerization: a unique tool towards polyethylene-based complex macromolecular architectures
Authors: Wang De , Zhang Zhen , Hadjichristidis Nikos
Published: May 2017

The recent developments in organoborane initiated C1 polymerization of ylides open unique horizons towards perfectly linear polymethylenes (equivalent to PE) and PE-based complex structures. This review summarizes research on conventional and newly discovered initiators/ylides, as well as initial efforts on C3 polymerization.
Photoresponsive liquid crystalline polymer single-chain nanoparticles
Authors: Fan Weizheng , Tong Xia , Li Guo , Zhao Yue
Published: May 2017

Single-chain nanoparticles prepared from a side-chain liquid crystalline polymer bearing azobenzene moieties can be multifunctional.
Introducing topology to assess the synchronicity of organic reactions. Dual reactivity of oximes with alkenes as a case study
Authors: Merino Pedro , Chiacchio Maria A. , Legnani Laura , Delso Ignacio , Tejero Tomas
Published: May 2017

Quantum chemical topology analyses provide a new way of understanding the synchronicity of organic reactions.
Synthesis of 1,2,3-triazoles in the presence of mixed Mg/Fe oxides and their evaluation as corrosion inhibitors of API 5L X70 steel submerged in HCl
Authors: Espinoza-Vázquez A. , Rodríguez-Gómez F. J. , Vergara-Arenas B. I. , Lomas-Romero L. , Angeles-Beltrán D. , Negrón-Silva G. E. , Morales-Serna J. A.
Published: May 2017

The 1-benzyl-4-phenyl-1,2,3-triazoles, synthesised from alkyne–azide cycloaddition in presence of mixed Mg/Fe oxides, exhibited excellent properties as corrosion inhibitors.
Biocompatible and biodegradable solid polymer electrolytes for high voltage and high temperature lithium batteries
Authors: Lin Yue , Cheng Yun , Li Jie , Miller Jan D. , Liu Jin , Wang Xuming
Published: May 2017

Wheat flour modified solid polymer electrolytes were synthesized and used in high safety and long cycling lithium batteries.
A moderate synthesis route of 5.6 mA-current LaB6 nanowire film with recoverable emission performance towards cold cathode electron source applications
Authors: Gan Haibo , Peng Luxi , Yang Xun , Tian Yan , Xu Ningsheng , Chen Jun , Liu Fei , Deng Shaozhi
Published: May 2017

The as-grown LaB6 nanowire arrays still remain a very large and stable emission current density over 16.7 mA cm−2 at high temperature as well as recoverable emission performances, which should have promising future in cold cathode electron sources.
Urea-assisted synthesis of hydroxyapatite nanorods from naturally occurring impure apatite rocks for biomedical applications
Authors: Wijesinghe W. P. S. L. , Mantilaka M. M. M. G. P. G. , Rajapakse R. M. G. , Pitawala H. M. T. G. A. , Premachandra T. N. , Herath H. M. T. U. , Rajapakse R. P. V. J. , Wijayantha K. G. Upul
Published: May 2017

Hydroxyapatite (HA) nanoparticles are heavily used materials in biomedical applications.
Interaction rule and mechanism of perfluoroalkyl sulfonates containing different carbon chains with human serum albumin
Authors: Liu Yang , Cao Zhaozhen , Zong Wansong , Liu Rutao
Published: May 2017

All three PFASs bind to HSA mainly through electrostatic forces and the toxicity decreases with the shortening of the carbon chain.
Solvothermal fabrication and growth behavior study of spherical MnFe2O4 through a bottom-up method on wood substrate with effective microwave absorption
Authors: Wang Hanwei , Wang Chao , Xiong Ye , Yao Qiufang , Chang Qing , Chen Yipeng , Jin Chunde , Sun Qingfeng
Published: May 2017

Spherical MnFe2O4 colloidal nanocrystal assemblies (CNAs) with different sizes were controllably fabricated on a wood substrate using a solvothermal method through a bottom-up pathway.
Highly efficient visible-light photocatalytic activity of MoS2–TiO2 mixtures hybrid photocatalyst and functional properties
Authors: Sabarinathan M. , Harish S. , Archana J. , Navaneethan M. , Ikeda H. , Hayakawa Y.
Published: May 2017

2D-layered molybdenum disulfide (MoS2) and MoS2/TiO2 nanocomposite were synthesized by a hydrothermal method.
Grain boundaries guided vibration wave propagation in polycrystalline graphene
Authors: Yang Zhi , Ma Fei , Xu Kewei
Published: May 2017

Propagation of mechanical stransverse wave in polycrystalline graphene sheet.
Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers
Authors: Young Lydia M. , Tu Ling-Hsien , Raleigh Daniel P. , Ashcroft Alison E. , Radford Sheena E.
Published: May 2017

Co-assembly into hetero-oligomers controls the lag time of amylin assembly by a mechanism reminiscent of prions.
Variation of the Fermi level and the electrostatic force of a metallic nanoparticle upon colliding with an electrode
Authors: Peljo Pekka , Manzanares José A. , Girault Hubert H.
Published: May 2017

The nanoparticle potential varies with the distance from the electrode, and sometimes like attracts like.
Modification of Li2MnSiO4cathode materials for lithium-ion batteries: a review
Authors: Cheng Qiaohuan , He Wen , Zhang Xudong , Li Mei , Wang Lianzhou
Published: May 2017

This review clearly highlights the recent advances of various synthetic and modification methods in improving the performances of Li2MnSiO4cathodes for LIBs.
A novel discharge–charge mechanism of a S–P2S5 composite electrode without electrolytes in all-solid-state Li/S batteries
Authors: Tanibata N. , Tsukasaki H. , Deguchi M. , Mori S. , Hayashi A. , Tatsumisago M.
Published: May 2017

A novel redox mechanism of a S–P2S5 composite electrode in all-solid-state Li/S batteries with extraordinarily high capacity is revealed.
High surface area, amorphous titania with reactive Ti3+ through a photo-assisted synthesis method for photocatalytic H2 generation
Authors: Zywitzki Dennis , Jing Hangkun , Tüysüz Harun , Chan Candace K.
Published: May 2017

A facile approach for the preparation of high surface area, Ti3+ containing titania with good activity for photocatalytic H2 production is reported.
Insight into the atomic structure of Li2MnO3 in Li-rich Mn-based cathode materials and the impact of its atomic arrangement on electrochemical performance
Authors: Song Yuanzhe , Zhao Xuebing , Wang Chao , Bi Han , Zhang Jie , Li Sesi , Wang Min , Che Renchao
Published: May 2017

Local heterogeneity in crystal lattice is directly observed in synthesized Li2MnO3/LiMO2 (M = Ni, Mn) cathode materials. With SAED application, for the first time, we accordingly uncover that the lattice heterogeneity is induced by different Li2MnO3 atomic arrangements coexisting in same crystal domain.
Transparent flexible lithium ion conducting solid polymer electrolyte
Authors: B. Puthirath Anand , Patra Sudeshna , Pal Shubhadeep , M. Manoj , Puthirath Balan Aravind , S. Jayalekshmi , Tharangattu N. Narayanan
Published: May 2017

Transparent, flexible, lithium ion conducting, freestanding, solid polymer electrolyte for solid state devices is developed based on polydimethylsiloxane, poly(ethylene oxide) and LiClO4, and the salting in phenomenon resulting in the amorphisation of the polymer matrix is established.
Platinum and indium sulfide-modified Cu3BiS3photocathode for photoelectrochemical hydrogen evolution
Authors: Kamimura Sunao , Beppu Naoki , Sasaki Yousuke , Tsubota Toshiki , Ohno Teruhisa
Published: May 2017

Platinum-deposited In2S3/Cu3BiS3film as a photoelectrode was fabricated on a molybdenum-coated glass substrate for photoelectrochemical hydrogen evolution.
Synthesis of poly(vinylidene fluoride–trifluoroethylene) via a controlled silyl radical reduction of poly(vinylidene fluoride–chlorotrifluoroethylene)
Authors: Zhang Wanwan , Wang Jian , Gao Pin , Tan Shaobo , Zhu Weiwei , Zhang Zhicheng
Published: May 2017

An environmentally friendly, controlled and metal-free process to synthesize P(VDF–TrFE) from P(VDF–CTFE) is successfully developed with tris(trimethylsilyl)silane.
Effective fabrication of flexible negative refractive index metamaterials using a simple screen printing method
Authors: Li Weiwei , Chen Mingji , Jin Hao , Liu Junchao , Zeng Zhihui , Zhang Hui , Zhang Zhong
Published: May 2017

Ag NPs arrays screen printed on flexible Kapton with smooth surface and excellent stability, are used to fabricate negative refractive index metamaterials.
Ambipolar D–A type bifunctional materials with hybridized local and charge-transfer excited state for high performance electroluminescence with EQE of 7.20% and CIEy ∼ 0.06
Authors: Liu Bin , Yu Zi-Wei , He Dan , Zhu Ze-Lin , Zheng Ji , Yu Ya-Dong , Xie Wen-Fa , Tong Qing-Xiao , Lee Chun-Sing
Published: May 2017

Achieving high-performance electroluminescence with EQE of 7.20% and CIEy∼ 0.06 based on bipolar materials with intercrossed excited state characteristics.
Core–shell metal fluoride nanoparticles via fluorolytic sol–gel synthesis – a fast and efficient construction kit
Authors: Ritter B. , Haida P. , Krahl T. , Scholz G. , Kemnitz E.
Published: May 2017

An efficient, fast and easy construction kit using the fluorolytic sol–gel synthesis of rare-earth-doped alkaline earth fluoride core–shell nanoparticles at room temperature is presented, capable of synthesizing several hundred grams to kilograms of core–shell particles in one batch.
Biological functions controlled by manganese redox changes in mononuclear Mn-dependent enzymes
Authors: Zhu Wen , Richards Nigel G.J.
Published: May 2017

Remarkably few enzymes are known to employ a mononuclear manganese ion that undergoes changes in redox state during catalysis. Many questions remain to be answered about the role of substrate binding and/or protein environment in modulating the redox properties of enzyme-bound Mn(II), the nature of the dioxygen species involved in the catalytic mechanism, and how these enzymes acquire Mn(II) given that many other metal ions in the cell form more stable protein complexes. Here, we summarize current knowledge concerning the structure and mechanism of five mononuclear manganese-dependent enzymes: superoxide dismutase, oxalate oxidase (OxOx), oxalate decarboxylase (OxDC), homoprotocatechuate 3,4-dioxygenase, and lipoxygenase (LOX). Spectroscopic measurements and/or computational studies suggest that Mn(III)/Mn(II) are the catalytically active oxidation states of the metal, and the importance of ‘second-shell’ hydrogen bonding interactions with metal ligands has been demonstrated for a number of examples. The ability of these enzymes to modulate the redox properties of the Mn(III)/Mn(II) couple, thereby allowing them to generate substrate-based radicals, appears essential for accessing diverse chemistries of fundamental importance to organisms in all branches of life.
Cluster assembly in nitrogenase
Authors: Sickerman Nathaniel S. , Rettberg Lee A. , Lee Chi Chung , Hu Yilin , Ribbe Markus W.
Published: May 2017

The versatile enzyme system nitrogenase accomplishes the challenging reduction of N2and other substrates through the use of two main metalloclusters. For molybdenum nitrogenase, the catalytic component NifDK contains the [Fe8S7]-core P-cluster and a [MoFe7S9C-homocitrate] cofactor called the M-cluster. These chemically unprecedented metalloclusters play a critical role in the reduction of N2, and both originate from [Fe4S4] clusters produced by the actions of NifS and NifU. Maturation of P-cluster begins with a pair of these [Fe4S4] clusters on NifDK called the P*-cluster. An accessory protein NifZ aids in P-cluster fusion, and reductive coupling is facilitated by NifH in a stepwise manner to form P-cluster on each half of NifDK. For M-cluster biosynthesis, two [Fe4S4] clusters on NifB are coupled with a carbon atom in a radical-SAM dependent process, and concomitant addition of a ‘ninth’ sulfur atom generates the [Fe8S9C]-core L-cluster. On the scaffold protein NifEN, L-cluster is matured to M-cluster by the addition of Mo and homocitrate provided by NifH. Finally, matured M-cluster in NifEN is directly transferred to NifDK, where a conformational change locks the cofactor in place. Mechanistic insights into these fascinating biosynthetic processes are detailed in this chapter.
Long-range proton-coupled electron transfer in the Escherichia coli class Ia ribonucleotide reductase
Authors: Reece Steven Y. , Seyedsayamdost Mohammad R.
Published: May 2017

Escherichia coli class Ia ribonucleotide reductase (RNR) catalyzes the conversion of nucleotides to 2′-deoxynucleotides using a radical mechanism. Each turnover requires radical transfer from an assembled diferric tyrosyl radical (Y•) cofactor to the enzyme active site over 35 Å away. This unprecedented reaction occurs via an amino acid radical hopping pathway spanning two protein subunits. To study the mechanism of radical transport in RNR, a suite of biochemical approaches have been developed, such as site-directed incorporation of unnatural amino acids with altered electronic properties and photochemical generation of radical intermediates. The resulting variant RNRs have been investigated using a variety of time-resolved physical techniques, including transient absorption and stopped-flow UV-Vis spectroscopy, as well as rapid freeze-quench EPR, ENDOR, and PELDOR spectroscopic methods. The data suggest that radical transport occurs via proton-coupled electron transfer (PCET) and that the protein structure has evolved to manage the proton and electron transfer co-ordinates in order to prevent ‘off-pathway’ reactivity and build-up of oxidised intermediates. Thus, precise design and control over the factors that govern PCET is key to enabling reversible and long-range charge transport by amino acid radicals in RNR.
Ion channels and ion selectivity
Authors: Roux Benoît
Published: May 2017

Specific macromolecular transport systems, ion channels and pumps, provide the pathways to facilitate and control the passage of ions across the lipid membrane. Ion channels provide energetically favourable passage for ions to diffuse rapidly and passively according to their electrochemical potential. Selective ion channels are essential for the excitability of biological membranes: the action potential is a transient phenomenon that reflects the rapid opening and closing of voltage-dependent Na+-selective and K+-selective channels. One of the most critical functional aspects of K+ channels is their ability to remain highly selective for K+ over Na+ while allowing high-throughput ion conduction at a rate close to the diffusion limit. Permeation through the K+ channel selectivity filter is believed to proceed as a ‘knockon’ mechanism, in which 2–3 K+ ions interspersed by water molecules move in a single file. Permeation through the comparatively wider and less selective Na+ channels also proceeds via a loosely coupled knockon mechanism, although the ions do not need to be fully dehydrated. While simple structural concepts are often invoked to rationalize the mechanism of ion selectivity, a deeper analysis shows that subtle effects play an important role in these flexible dynamical structures.
Transition metals at the host–pathogen interface: howNeisseriaexploit human metalloproteins for acquiring iron and zinc
Authors: Neumann Wilma , Hadley Rose C. , Nolan Elizabeth M.
Published: May 2017

Transition metals are essential nutrients for all organisms and important players in the host–microbe interaction. During bacterial infection, a tug-of-war between the host and microbe for nutrient metals occurs: the host innate immune system responds to the pathogen by reducing metal availability and the pathogen tries to outmaneuver this response. The outcome of this competition, which involves metal-sequestering host-defense proteins and microbial metal acquisition machinery, is an important determinant for whether infection occurs. One strategy bacterial pathogens employ to overcome metal restriction involves hijacking abundant host metalloproteins. The obligate human pathogens Neisseria meningitidis and N. gonorrhoeae express TonB-dependent transport systems that capture human metalloproteins, extract the bound metal ions, and deliver these nutrients into the bacterial cell. This review highlights structural and mechanistic investigations that provide insights into how Neisseria acquire iron from the Fe(III)-transport protein transferrin (TF), the Fe(III)-chelating host-defense protein lactoferrin (LF), and the oxygen-transport protein hemoglobin (Hb), and obtain zinc from the metal-sequestering antimicrobial protein calprotectin (CP).
Efficient CRC concatenation scheme for polar codes
Authors: Qingshuang Zhang , Aijun Liu , Xiaofei Pan
Published: May 2017

A new cyclic redundancy check (CRC) concatenation with polar codes based on partial protection is proposed, where only the crucial bits chosen from the total information bits are protected with the CRC. The index set of crucial bits is determined by the row weight of generator matrix of polar codes and the indexes with minimum row weight make up this crucial set. Using this new concatenation, the number of polar codewords with minimum Hamming weight can be efficiently decreased. Simulation results show that the performance of the proposed partial protection scheme owns a lower error floor than that of the classical blind protection.
Miniaturised highly selective bandpass filter with very wide stopband using meander coupled lines
Authors: Killamsetty V.K. , Mukherjee B.
Published: May 2017

A compact wideband bandpass filter with a very wide stopband for terrestrial radio (TETRA) band applications is proposed. The proposed filter employs two types of resonators: one is tri‐section half wavelength stepped impedance resonator (SIR) and the other is stub‐loaded shorted ring resonator. The proposed filter has adopted SIRs and meandering technique in achieving miniaturised size. Spur‐lines and tapped feeding techniques are infused in the filter to suppress harmonics so as to achieve wide stopband. Cross‐coupling is introduced in the filter for acquiring good selectivity. This highly selective filter has a miniaturised size of 0.09 × 0.12λg (28 × 36.8 mm2) with a wide stopband up to 8.75f0 (f0 is the centre frequency of filter) with 25 dB harmonics suppression level.
Analysis and design of a soft‐switching boost DC/DC converter
Authors: Babaei Ebrahim , Abbasnezhad Amin , Sabahi Mehran , Hosseini Seyed Hossein
Published: May 2017

The analysis and design considerations of a soft‐switching boost dc/dc converter have been presented. Operating principles of the converter have been completely presented, as well as the thorough analysis of the operating modes. In the analyses, all the equations related to the voltages and currents of the elements have been attained, and by using these equations the maximum values of them have been calculated. In the proposed structure, due to the resonant circuit, which consists of an inductor and two capacitors, the switches are turned on with zero voltage. In addition to the operating modes analysis, the values needed for the resonant elements have been calculated, and the design considerations have been presented in detail. One of the advantages of the proposed converter is the decrease in switching losses, besides the reduction of the voltage and current stresses of the circuit components, due to soft‐switching feature. Another advantage of the proposed structure is its high switching frequency. In this literature, in order to evaluate the advantages and disadvantages of the proposed structure, there has been made a comparison with the conventional topologies. Moreover, the correctness of the presented analyses has been validated by experimental and simulation results, using PSCAD/EMTDC software.
An Alternative Synthesis of Bipyrenol: A High-Yield Oxidative Coupling Reaction of a Pyrene Derivative with Cu(BF4)2·nH2O
Authors: Sugiura Ken-ichi , Rajbangshi Subas
Published: May 2017

An alternative synthesis has been developed with the objective of extending the applications of bipyrenol in mind. The key reaction involves the oxidative coupling of 2-hydroxypyrene menthyl carbonate to afford the corresponding pyrene dimer. In marked contrast to our previous method, i.e., the oxidation of 2-hydroxypyrene, the revised method is a clean and high-yielding reaction. By optimizing the reaction conditions, the yield of the alternative synthesis is increased to 88%.
Copper-Catalyzed Intramolecular C–H Amination: A New Entry to Substituted Xanthine Derivatives
Authors: Inamoto Kiyofumi , Shimizu Maki , Hayama Noboru , Kimachi Tetsutaro
Published: May 2017

Catalytic synthesis of xanthines was achieved in the presence of a copper catalyst. The process involves copper-catalyzed intramolecular C–H amination of benzamidines that possess a uracil moiety and produces variously substituted xanthines generally in good to high yields. This work introduces a new, facile approach to polysubstituted xanthine compounds.