bluuebunny/crossref_metadata_2025 huggingface dataset:
How to Bridge the Gaps between Competing Paradigms for EU Law: An Introduction
Authors: Simoncini Marta , Straetmans Gert
Published: November 2017

For the first time since its creation, the European Union (EU) has been living its probably most significant identity crisis. This crisis has its roots in different critical situations that have hit the EU, have affected its functioning and have fundamentally questioned its legitimacy. The gaps in the EU integration process have been uncovered and the fragmentation of EU policies has become a source of different risks.

On the anniversary of sixty years of the Rome Treaties, this Special Issue aims to reflect on the paradigms for EU law looking beyond their competing accounts of EU integration. The analysis is developed through a series of contributions that challenge the paradigms in different directions. The discussion is articulated on two levels. On the one hand, a group of contributions focuses on the historical and legal analysis of the emergence and transformation of the EU legal order. These contributions delve deeper into the absence of a European identity and go beyond the inherent critique that the EU is ademoi-cracy that struggles with a democratic disconnect or even deficit. On the other hand, other contributions debate paradigms and their implementation in important policy domains. These contributions aim to give a more practical perspective on the constitutional and/or administrative character of the European Union, showing its implications and concrete questions.
Assessment of R18, COG1410, and APP96-110 in excitotoxicity and traumatic brain injury
Authors: Chiu Li Shan , Anderton Ryan S. , Cross Jane L. , Clark Vince W. , Edwards Adam B. , Knuckey Neville W. , Meloni Bruno P.
Published: November 2017

Cationic arginine-rich and poly-arginine peptides (referred to as CARPs) have potent neuroprotective properties in in vitro excitotoxicity and in vivo models of stroke. Traumatic brain injury (TBI) shares many pathophysiological processes as stroke, including excitotoxicity. Therefore, we evaluated our lead peptide, poly-arginine R18, with the COG1410 and APP96-110 peptides, which have neuroprotective actions following TBI. In an in vitro cortical neuronal glutamic acid excitotoxicity injury model, R18 was highly neuroprotective and reduced neuronal calcium influx, while COG1410 and APP96-110 displayed modest neuroprotection and were less effective at reducing calcium influx. In an impact-acceleration closed-head injury model (Marmarou model), R18, COG1410, and APP96-110 were administered intravenously (300 nmol/kg) at 30 minutes after injury in male Sprague-Dawley rats. When compared to vehicle, no peptide significantly improved functional outcomes, however the R18 and COG1410 treatment groups displayed positive trends in the adhesive tape test and rotarod assessments. Similarly, no peptide had a significant effect on hippocampal neuronal loss, however a significant reduction in axonal injury was observed for R18 and COG1410. In conclusion, this study has demonstrated that R18 is significantly more effective than COG1410 and APP96-110 at reducing neuronal injury and calcium influx following excitotoxicity, and that both R18 and COG1410 reduce axonal injury following TBI. Additional dose response and treatment time course studies are required to further assess the efficacy of R18 in TBI.
Paul Silas Peterson: A third time, Erich Przywara, the Jews and Stimmen der Zeit: With a response to Aaron Pidel and a brief look into Przywara’s late letters to Carl Schmitt
Authors: Peterson Paul Silas
Published: November 2017

In diesem Aufsatz werden die Veröffentlichungen des Jesuiten Erich Przywara und der sehr einflussreichen jesuitischen Zeitschrift Stimmen der Zeit aus den frühen 193oern Jahren und besonders aus dem Jahr 1933 analysiert. In diesem Zusammenhang antworte ich auch meinen Kritikern. Außerdem werden die Hintergründe und Quellen der spezifischen Form des Antisemitismus dargestellt, die in den Stimmen der Zeit vertreten wurde. Deutsche Jesuiten propagierten 1933 durchaus radikale Positionen in der Zeitschrift. In dem katholischen Blatt liest man u. a., dass die Juden dem deutschen Volk mehr Schaden als Nutzen brächten. Es wurde damals auch die nordische Rasse als für Herrschaft besonders geeignet bezeichnet. Im letzten Teil dieses Aufsatzes werden Przywaras spätere Briefe an Carl Schmitt, den gläubigen antisemitischen deutschen Katholiken, analysiert. Sie zeigen, dass Przywara von dessen antidemokratischer politischer Theorie der 1930er Jahre zutiefst beeindruckt war und die Ideen des Kronjuristen des Dritten Reiches sogar noch in der Zeit nach dem Zweiten Weltkrieg verbreiten wollte.
A survey on the perceived need and value of decision-support tools for joint mitigation of air pollution and climate change in cities
Authors: von Schneidemesser Erika , Kutzner Rebecca D. , Schmale† Julia
Published: November 2017

Decision-support tools are increasingly popular for informing policy decisions linked to environmental issues. For example, a number of decision-support tools on transport planning provide information on expected effects of different measures (actions, policies, or interventions) on air quality, often combined with information on noise pollution or mitigation costs. These tools range in complexity and scale of applicability, from city to international, and include one or several polluting sectors. However, evaluation of the need and utility of tools to support decisions on such linked issues is often lacking, especially for tools intended to support local authorities at the city scale. Here we assessed the need for and value of combining air pollution and climate change mitigation measures into one decision-support tool and the existing policy context in which such a tool might be used. We developed a prototype decision-support tool for evaluating measures for coordinated management of air quality and climate change; and administered a survey in which respondents used the prototype to answer questions about demand for such tools and requirements to make them useful. Additionally, the survey asked questions about participants’ awareness of linkages between air pollution and climate change that are crucial for considering synergies and trade-offs among mitigation measures. Participants showed a high understanding of the linkages between air pollution and climate change, especially recognizing that emissions of greenhouse gases and air pollutants come from the same source. Survey participants were: European, predominantly German; employed across a range of governmental, non-governmental and research organizations; and responsible for a diversity of issues, primarily involving climate change, air pollution or environment. Survey results showed a lack of awareness of decision-support tools and little implementation or regular use. However, respondents expressed a general need for such tools while also recognizing barriers to their implementation, such as limited legal support or lack of time, finances, or manpower. The main barrier identified through this study is the mismatch between detailed information needed from such tools to make them useful at the local implementation scale and the coarser scale information readily available for developing such tools. Significant research efforts at the local scale would be needed to populate decision-support tools with salient mitigation alternatives at the location of implementation. Although global- or regional-scale information can motivate local action towards sustainability, effective on-the-ground implementation of coordinated measures requires knowledge of local circumstances and impacts, calling for active engagement of the local research communities.
Diatoms in lung tissue: first investigation in Brazil in proving death by drowning
Authors: Carneiro Nicole P.M. , Torgan L. C. , Vaz M. , Utz L. P.
Published: November 2017

Diatoms are microalgae widely distributed in inland and marine waters and during drowning they are inhaled together with water, passing through the bloodstream to various internal organs of a victim. Our investigation aimed to evaluate the diatoms extracted from the lung tissues of an individual with drowning diagnosis and compare them to those found in the environment, in order to prove the cause of death and the drowning site. A left lung fragment of 17.9 grams removed from the victim was oxidized and prepared for diatoms identification and quantification using inverted microscope. A total of 133 diatoms valves was found, being 85% belong to pennate forms and 15% to centric forms. Pinnularia, a bentonic genus, had greatest number of valves, followed by Fragilaria, Actinocyclus, Cocconeis and Encyonema. These results revealed that the victim drowned at the bottom of the lake, inhaling both water and sediments with diatoms. This is the first investigation of this nature carried out in Brazil.
A interferência da solução de luminol em teste imunocromatográfico para pesquisa de sangue humano
Authors: Vaz Vanessa Silva , Kobachuck L.D.G.
Published: November 2017

As manchas de sangue muitas vezes são limpas nas cenas de crime, e um dos métodos para identificação de sangue latente é o luminol, o qual possui alta sensibilidade, porém, pouca especificidade, e por esse motivo, deve ser acompanhado de um método de confirmação. Este estudo teve como objetivo analisar a possível interferência do teste presuntivo luminol, preparado de acordo com a formulação de Grodsky sobre o teste confirmatório imunocromatográfico (WAMA®) para pesquisa de sangue humano e verificar a sensibilidade de ambos os testes. Diferentes diluições de uma amostra de sangue humano foram depositadas sobre fragmentos de tecido de algodão branco, deixadas secar por 24 horas em temperatura ambiente e, em seguida, foram submetidas aos dois métodos. Após as amostras terem sido pulverizadas com luminol, a diluição 1:1.000 não mostrou interferência no teste feito imediatamente após a pulverização, porém após 24 horas a interferência foi observada. Na diluição 1:10.000 houve interferência imediata no teste imunocromatográfico e o resultado persistiu após 24 horas. Já as diluições de 1: 50.000 e 1:100.000 tanto o controle positivo quanto a amostra pulverizada por luminol apresentaram resultados negativos imediatamente e após 24 horas no teste imunocromatográfico. Resultado positivo para o teste de luminol com emissão de quimiluminescência foi obtido até a concentração 1:50.000 e o teste imunocromatográfico mostrou-se positivo até a diluição 1:10.000, indicando que realmente há uma diferença de sensibilidade entre os métodos.
Genotyping by Sequencing in Almond: SNP Discovery, Linkage Mapping, and Marker Design
Authors: Goonetilleke Shashi N , March Timothy J , Wirthensohn Michelle G , Arús Pere , Walker Amanda R , Mather Diane E
Published: November 2017

In crop plant genetics, linkage maps provide the basis for the mapping of loci that affect important traits and for the selection of markers to be applied in crop improvement. In outcrossing species such as almond (Prunus dulcis Mill. D. A. Webb), application of a double pseudotestcross mapping approach to the F1 progeny of a biparental cross leads to the construction of a linkage map for each parent. Here, we report on the application of genotyping by sequencing to discover and map single nucleotide polymorphisms in the almond cultivars “Nonpareil” and “Lauranne.” Allele-specific marker assays were developed for 309 tag pairs. Application of these assays to 231 Nonpareil × Lauranne F1 progeny provided robust linkage maps for each parent. Analysis of phenotypic data for shell hardness demonstrated the utility of these maps for quantitative trait locus mapping. Comparison of these maps to the peach genome assembly confirmed high synteny and collinearity between the peach and almond genomes. The marker assays were applied to progeny from several other Nonpareil crosses, providing the basis for a composite linkage map of Nonpareil. Applications of the assays to a panel of almond clones and a panel of rootstocks used for almond production demonstrated the broad applicability of the markers and provide subsets of markers that could be used to discriminate among accessions. The sequence-based linkage maps and single nucleotide polymorphism assays presented here could be useful resources for the genetic analysis and genetic improvement of almond.
RNA-Sequencing ofDrosophila melanogasterHead Tissue on High-Sugar and High-Fat Diets
Authors: Hemphill Wayne , Rivera Osvaldo , Talbert Matthew
Published: November 2017

Obesity has been shown to increase risk for cardiovascular disease and type-2 diabetes. In addition, it has been implicated in aggravation of neurological conditions such as Alzheimer’s. In the model organism Drosophila melanogaster, a physiological state mimicking diet-induced obesity can be induced by subjecting fruit flies to a solid medium disproportionately higher in sugar than protein, or that has been supplemented with a rich source of saturated fat. These flies can exhibit increased circulating glucose levels, increased triglyceride content, insulin-like peptide resistance, and behavior indicative of neurological decline. We subjected flies to variants of the high-sugar diet, high-fat diet, or normal (control) diet, followed by a total RNA extraction from fly heads of each diet group for the purpose of Poly-A selected RNA-Sequencing. Our objective was to identify the effects of obesogenic diets on transcriptome patterns, how they differed between obesogenic diets, and identify genes that may relate to pathogenesis accompanying an obesity-like state. Gene ontology analysis indicated an overrepresentation of affected genes associated with immunity, metabolism, and hemocyanin in the high-fat diet group, and CHK, cell cycle activity, and DNA binding and transcription in the high-sugar diet group. Our results also indicate differences in the effects of the high-fat diet and high-sugar diet on expression profiles in head tissue of flies, despite the reportedly similar phenotypic impacts of the diets. The impacted genes, and how they may relate to pathogenesis in the Drosophila obesity-like state, warrant further experimental investigation.
Diagnosing Infection in a Neonate Using Whole-Body Screening Magnetic Resonance Imaging
Authors: Fu Ting Ting , Kingma Paul S.
Published: November 2017

The location of invasive infections is difficult to detect in infants, in part due to their inability to localize signs and symptoms. However, identifying the location often significantly alters clinical management by extending the duration of antibiotic therapy or revealing a source requiring surgical intervention. Compared with commonly used first-line imaging techniques such as radiographs and ultrasounds, MRI has higher sensitivity for identifying invasive infections and allows for simultaneous evaluation of multiple foci. We present 2 cases in which whole-body screening MRI was used in neonates to identify invasive sources of infection, including one in which traditional modalities failed to detect multiple clinically significant sources. We posit that whole-body screening MRI merits consideration as a potential first-line imaging method when investigating invasive infections in infants.
A PERCEPÇÃO DOS SERVIDORES PÚBLICOS SOBRE A SOCIALIZAÇÃO ORGANIZACIONAL: UM ESTUDO NO INSTITUTO FEDERAL DE EDUCAÇÃO, CIÊNCIA E TECNOLOGIA DO RIO GRANDE DO SUL
Authors: Genari Denise , Ibrahim Camila Vanessa Dobrovolski , Ibrahim Gibran Fernando
Published: November 2017

As instituições públicas, atualmente, têm enfrentado desafios específicos para atrair, desenvolver e reter seus profissionais. Neste contexto, pode-se destacar a importância do processo de socialização organizacional, uma vez que este possibilita que o indivíduo se familiarize com a cultura da instituição, compreenda os valores por ela praticados e adquira conhecimentos e habilidades necessárias para assumir seu papel na corporação. Diante destas afirmativas, o presente estudo tem por objetivo identificar a percepção dos servidores públicos do IFRS (Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul) sobre o processo de socialização organizacional praticado pela instituição. Para tanto, realizou-se uma pesquisa de cunho quantitativo e descritivo, durante o ano de 2015, com a participação de uma amostra de 101 servidores vinculados à organização. Como principais resultados, é possível destacar a oportunidade de desenvolvimento de um programa de socialização mais abrangente, aprofundando o treinamento introdutório nas tarefas e o maior envolvimento das chefias. Além disso, identificou-se que as variáveis relacionadas ao acesso às informações, à integração às pessoas e ao conhecimento da linguagem e tradições da instituição apresentaram menores escores quando relacionadas ao processo de socialização. Em contrapartida, a qualificação dos profissionais se manifestou como um dos fatores potencialmente favorável à socialização na organização objeto deste estudo. A partir dos resultados evidenciados, espera-se contribuir para a construção de um programa de socialização organizacional mais efetivo e direcionado às necessidades do IFRS.
The Vocation to Parenthood in the Context of a Demographic Crisis in Poland
Authors: Świerczek Antoni
Published: November 2017

The vocation to parenthood is a constitutive element of married and family life. However, recent decades show that the number of births in Poland is declining steadily. This, in turn, is leading to a decrease in population and population aging in our homeland. The current situation is called a demographic catastrophe, the consequences of which will be felt in the next decades. It is therefore necessary to take concrete steps to change this situation. The aims of this article are to try to describe the present demographic situation in Poland, to recall the main ideas of the teaching of the Catholic Church on the parental tasks of the family and society, and to identify the most important pastoral task, which the Church in Poland faces in this regard.
The Dilemmas of Christian Feminism
Authors: Świerczek Magdalena
Published: November 2017

The aim of the article is to discuss selected issues of Christian feminism which attempt to reconcile traditional women’s roles in a society with the idea of emancipation. The article is composed of four parts. The first one discusses the basic theses of Christian feminism. The second one includes deliberations on biblical and theological evidence for women’s and men’s statuses. The third and fourth part offer an analysis of biblical examples of women’s autonomy and the postulate of women’s emancipation in the Christian work ethos.
Muzyka sakralna jako via pulchritudinis wyzwaniem dla kompozytorów
Authors: Bramorski Jacek
Published: November 2017

Jeśli natura i kosmos są odblaskiem piękna Stwórcy i prowadzą nas do kontemplacji Jego wielkości, to również twórczość artystyczna ma możliwość przybliżania nas do tajemnicy Boga. Dla człowieka wierzącego piękno wykracza poza estetykę i odnajduje swój archetyp w Bogu. Kontemplacja odwiecznej piękności jest źródłem, z którego kompozytorzy chrześcijańscy czerpią natchnienie, aby ukazywać w swej twórczości misterium Boga. Inspirowane wiarą chrześcijańską dzieła muzyki sakralnej pozwalają nam w intuicyjny sposób uczestniczyć w doświadczeniu wiary, odkrywając tajemnicę miłości Boga i tożsamości człowieka. Posługując się językiem piękna, dzieła muzyczne są nie tylko nośnikami przesłania artysty, ale także prawdy o Bogu. Kompozytor, ukazując ową prawdę, nie wychwala samego siebie, ale pragnie uwielbiać Źródło Piękna. W liturgii, będącej istotnym momentem w doświadczaniu dojrzałej wiary, piękna nie można zredukować jedynie do formalnego estetyzmu. Jest to przede wszystkim głębokie piękno spotkania z tajemnicą Boga. Dlatego w muzyce liturgicznej nie ma miejsca na powierzchowność, banalność i niedbałość. Muzyka nie pomagałaby wówczas w rozwoju wiary, ale wręcz stawałaby się przeszkodą w godnym uczestniczeniu w chrześcijańskich obrzędach. Piękno stanowi zatem jedną z fundamentalnych kategorii teologicznych, pomagając wzrastać w wierze oraz dążyć do prawdy. Istotną rolę ewangelizacyjną pełni w tym kontekście muzyka sakralna, która jako via pulchritudinis stanowi wspaniały wyraz wiary, nadziei i miłości.
Instytucja Kościoła w przestrzeni muzycznej Feliksa Nowowiejskiego
Authors: Dulisz Ilona
Published: November 2017

Życie i twórczość Feliksa Nowowiejskiego, czołowego kompozytora muzyki religijnej pierwszej połowy XX w. w Polsce, nierozerwalnie wiąże się z Kościołem katolickim. Religijna atmosfera domu rodzinnego, nauka w placówkach kościelnych, praca na stanowiskach organisty, szerokie kontakty w kręgach duchowieństwa, w tym z najwyższymi hierarchami kościelnymi, to istotne determinanty działalności artystycznej kompozytora. W latach II Rzeczypospolitej Nowowiejski nieustanne obecny był w życiu Kościoła i Narodu Polskiego, dla którego Bóg i Ojczyzna stanowiły jedność. Ogromny dorobek kompozytorski, wyrosły w dużej mierze z tradycji religijnych, przyniósł mu liczne nagrody i wyróżnienia.
Poznanie naukowe a prawda absolutna. Krytyka argumentu za istnieniem Boga Siemiona L. Franka
Authors: Sajdek Zofia
Published: November 2017

According to a Russian philosopher Siemion Frank, there is no such thing as “truth” in science without making a pre­‑assumption about the existence of some kind absolute, and in Frank’s eyes “absolute” always equals “God”. That is why you cannot be an atheist and scientist at the same time. The article is an attempt to show that it is not a proper notion of what science is or should be because: 1) science does not need any idea of truth (maybe philosophy of science does), 2) a consistent notion of truth can be formulated without any notion of absolute, 3) “absolute” not always equals “God”, or even “transcendence”.
Temperature and pressure effects on basalt thermal diffusivity – a review
Authors: Zhang Y. , Sun Q.
Published: November 2017

Studying basalt thermal diffusivity under high temperature or high pressure is helpful to understand the lithospheric thermal structure and dynamics of subduction zone and to evaluate the heat-transmission mechanisms in basalt stratum. To explore the temperature and pressure effects on basalt thermal diffusivity, the authors collected data from literature reviews. A decrease in the basalt thermal diffusivity by an elevated temperature was obtained by an exponential function. An increase in basalt thermal diffusivity by pressure was found. The internal reasons of these two findings were explained by a classical physics theory. Moreover, the physical property changes by temperature and pressure are also the reasons of thermal-diffusivity change, which include crack generation, increase in porosity and decrease in density at elevated temperature and crack close, porosity decrease and grain contact under pressure.
The Effect of Perceived Quality, Revisit Intention and Premium Payment Intention on Korean Restaurants: Focused on Mediation Effect of Experience Value
Authors:   The Tourism Sciences Society Of Korea, Kim Jin-Hee , Lee Soo-Bum
Published: November 2017

The purpose of this study was to investigate the effect of perceived quality, revisit intention and premium payment intention in a selected group of Korean restaurants. The focus was on the mediating effect of experiential value on perceived quality, revisit intentions and premium payment intentions. For the purpose of this study, a questionnaire was distributed to a total of 320 participants residing throughout Seoul and Gyeonggi-do utilizing Korean restaurants in these areas. In total, 273 samples were deemed valid and these questionnaires were analyzed. The results showed first that the perceived quality of Korean restaurants and experiential value is divided into the four following factors: 1) Service quality, 2) Food quality, 3) Space layout, and 4) Atmosphere. Secondly, perceived quality influenced experiential value, revisit intention, and the premium payment intention. Thirdly, experiential value influenced revisit intention and premium payment intention. Fourthly, these results showed that the experiential value was a moderating factor between perceived quality and revisit intention. However, experiential value was not a moderating factor between perceived quality and premium payment intention.
Trends and patterns of Antibiotic Consumption in China’s Tertiary Hospitals: based on a 5 year surveillance with sales records, 2011-2015 v3
Authors: Wushouer Haishaerjiang , Tian Ye , Guan Xiao-Dong , Han Sheng , Shi Lu-Wen
Published: November 2017

The consumption of antibiotics is a major driver for the development of antibiotic resistance in bacteria. We identified the trends and patterns of total antibiotic consumption in China’s tertiary hospitals from 2011 to 2015. We retrospectively analyzed aggregated monthly surveillance data on antibiotic sales made to 468 hospitals from 28 provinces. Antibiotic consumption was expressed in DDD per 1000 inhabitants per day (DID). We compared population weighted antibiotic consumption patterns in China with European countries using indicators from the European Surveillance of Antimicrobial Consumption (ESAC). Total antibiotic consumption in general, including all the specific antibiotic class except for aminoglycoside antibacterials, were significantly increased during the study period from an average of 7.97 DID in 2011 to 10.08 DID in 2015. In 2015, eastern regions consumed the most antibiotics if using population based calculation while west regions consumed the most using inpatient volume based calculation. Cephalosporins accounted for 28.6% of total DID, followed by beta-lactam-beta-lactamase inhibitor combinations with 20.0%, macrolides with 17.4%, and fluoroquinolones with 10.5%. Antibiotic in parenteral form were accounted for nearly half of all antibiotics. We used aggregated sales records data to monitor antibiotic consumption across China over a 6 year period. Although great efforts had been made through antibiotic stewardship in the past few years, total antibiotic consumption showed a significant upward trend during the study period. A consistent preferences for cephalosporins, macrolides, beta-lactam-beta-lactamase inhibitor combinations, as well as parenteral preparations was observed. More efforts are needed in the future to investigate the quality of antibiotic prescribing.
Agentenbasierte Testplanung für industrielle IT-Systeme in der Fertigung
Authors: Abele Sebastian , Zeller Andreas , Jazdi Nasser , Weyrich Michael
Published: November 2017

Mit steigendem Funktionsumfang erhöht sich die Komplexität von industriellen IT-Systemen. Dabei stellt die verteilte Entwicklung der Systeme und der Einsatz in unterschiedlichen Varianten eine Herausforderung dar. Bei der Koordination des Systemtests fehlt es oft am Abgleich von Testdaten. So stehen meist nicht ausreichend Daten zur Verfügung, um einen Überblick über den Testfortschritt zu erhalten. Im Beitrag wird ein Konzept für ein agentenbasiertes Assistenzsystem beschrieben, das sich im gesamten Entwicklungs- und Zuliefernetzwerk verteilt einsetzen lässt. Dadurch können eine umfassende Übersicht über den aktuellen Testfortschritt erhalten und Testfälle für den Regressionstest priorisiert werden.
Role of Self-Reflection in the Process of Student Adaptation to University
Authors: Grigoryeva M.V. , Shamionov R.M. , Golubeva N.M.
Published: November 2017

The article considers the problem of determining the role of self-reflection in the process of adaptation of students to the conditions of study at university. It is suggested that the specifics of self-reflection depend on the outcomes of social psychological adaptation of students in the educational environment of university. The study involved 320 students (average age — 24.1 years old, SD = 6.8, males — 10.3%). The following standardized techniques were used: studies on student adaptation at university (T.D. Dubovitskaya, A.V. Krylova), diagnostics of social psychological adaptation (K. Rogers, R. Diamond), measures of selfreflection level (A.V. Karpov, V. V. Ponomaryova), and custom-developed scales for evaluating self-reflective activity. The study revealed that self-reflective activity and situational, retrospective, and perspective self-reflection are specific for welladapted students as well as for students with difficulties in adaptation. It is clear that regulation of dynamics of self-reflective images is important for the process of adaptation to university, allowing the individual to combine the dynamics necessary for quick response to changes in the situation and sufficient stability and clarity for understanding and creating motivation.
Specifics of Teachers’ Attitude to Students with Different Status in School Class
Authors: Sachkova M.Y.
Published: November 2017

The paper presents outcomes of an empirical research on general education teachers’ attitudes to students with different status in school class. The issue of teachers’ evaluation of middle status members of student groups was of special interest. The research involved a set of social psychological techniques: parametric sociometry, autosociometry, parametric reference measurement tool, autoreference measurement tool, a tool for measuring informal intragroup power structure in contact community, and G. Kelly’s Repertory Grid Technique (modification). The subjects were 126 teachers of 5—11 grades of Moscow schools, with work experience ranging from 3 to 38 years. As it was revealed, the teachers adequately perceive the status structure of the class; however, they tend to poorly differentiate the category of middle status students. The paper also discusses the features of the teachers’ emotional attitude to the students depending on the latter’s status in the student group.
Psychological and Pedagogical Measures of Preventing Conflicts of Interest Among Employees of Law Enforcement Agencies
Authors: Serdyuk N.V. , Naumov Y.G. , Grishenko L.L.
Published: November 2017

The article considers significant characteristics of the phenomenon of corruption resistance of employees of internal affairs agencies as civil servants. The outlined problem of preventing corruption manifestations and conflicts of interests in operational and service activities is characterized by the fact that it exceeds the limits of legal regulation. The possible solution in this case might be the selection of relevant psychological and pedagogical measures of preventing the conflict of interests and the formation of corruption resistance in the personnel of the internal affairs bodies. The article describes the value basis of law enforcement service and personal meanings in the profession.
Los valores transmitidos por las mujeres en las películas Disney
Authors: Marín Díaz Verónica , Solís Concepción
Published: November 2017

The animated films, has taken in the last decade of great relevance. This study aims to analyse the values that the female of the films from Disney. Through a descriptive and correlational study, we have proceeded to consult a group of teachers (N = 27) of said educational level, through a questionnaire of Marin and Sanchez (2015). The main result achieved has been the realization of the development of women and their role in society. It has also been confirmed that all transmit at least one traditional socially accepted value.
Ciudadanía: análisis de algunos elementos del Modelo de Responsabilidad Social Universitaria en una universidad pública
Authors: Evia Alamilla Nancy Marine , Echeverría Echeverría Rebelín , Carrillo Trujillo Carlos David , Quintal López Rocío
Published: November 2017

The higher education of the present century faces several challenges in the different areas that comprise it, from management, administration, habilitation and training to what is related to the social dynamics of the educational community, the curricular contents that are transmitted, the educational philosophy Adopted, the resources and strategies for the achievement of its institutional objectives, among others. In addition to this we find questions such as: What are the contents that are necessary to understand the current reality? Who are the students in training? What type of training is offered at the university? Do your objectives contribute to addressing emerging world situations? In this article an analysis is made of some elements of the University Social Responsibility Model of a public university, which is operated in the curriculum through an institutional educational program. Program that forms part of the actions of the Institutional Development Plan of said University. Finally, lines of action are established for the strengthening of the model.
Hacia una nueva mirada de la reintegración de desmovilizados en Colombia: conceptos, enfoques y posibilidades
Authors: Mesa Juan David
Published: November 2017

This article shows that the public policy agenda of reintegration in Colombia has been closely linked to the international mandate of the Disarmament, Demobilization and Reintegration program, which takes the process in a homogeneous way without considering the unique aspects of demobilized persons (their group of origin, gender, race, among others). It is also pointed out that the academic agenda of reintegration in Colombia, which has been in charge of diagnosing the above, is still in a phase of legal-political discussion because it has concentrated on the legal frameworks, institutionalist and comparative studies of the Process, from a fundamentally structural-functionalist theoretical bet. To that extent, an alternative theoretical-methodological approach is proposed, from the pragmatism of Hans Joas's theory of creative action, starting from the positive aspects and the reformulation of the most problematic of the state of the matter.
Main Serological Markers of Systemic Rheumatic Autoimmune Diseases
Authors: Souza Weuley Pereira de , Carneiro Cristiene Costa , Passos Xisto Sena
Published: November 2017

Abstract: Systemic rheumatic autoimmune diseases are complex chronic inflammatory disorders, generally with impairment of joins and systemic manifestations. This study is a literature review about the main serologic markers used in the screening of these illnesses. The assessment of the presence of autoantibodies is an essential component in the initial diagnosis of autoimmune diseases. The production of these antibodies occurs via humoral immune response against self-antigens, and these antibodies are often present in the serum of patients diagnosed with autoimmune illness. Each antibody has a different function and specificity and this is directly associated with clinic manifestations and disease course. The main markers detected in rheumatology have antinuclear, prothrombotic and inflammatory action; therefore depending on the complexity of the illness, several markers can be identified, assisting both in diagnosis and prognosis disease.

Keywords: Autoantibodies. Antinuclear antibodies. Serologic markers. Autoimmune rheumatic diseases.

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Principais marcadores sorológicos de doenças reumáticas autoimunes sistêmicas

Resumo: Doenças reumáticas autoimunes sistêmicas são doenças inflamatórias crônicas, complexas, geralmente com comprometimento das articulações acompanhado de manifestações sistêmicas. O presente estudo trata-se de uma revisão bibliográfica sobre os principais marcadores sorológicos utilizados no rastreio dessas doenças. A avaliação da presença de autoanticorpos constitui parte essencial no diagnóstico inicial de doenças autoimunes. A produção desses anticorpos ocorre através de resposta imune humoral contra antígenos próprios, e estão frequentemente presentes no soro de pacientes diagnosticados com doença autoimune. Cada anticorpo tem função, e especificidade diferentes, e isso influencia diretamente na manifestação e curso da doença. Os principais marcadores detectados em reumatologia têm ação antinuclear, pró-trombótica e inflamatória, por isso, dependendo da complexidade da doença, vários marcadores podem ser encontrados, auxiliando tanto no diagnóstico quanto no prognóstico.

Palavras-chave: Autoanticorpos. Anticorpos antinucleares. Marcadores sorológicos. Doenças reumáticas autoimunes.

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■ Text in Portuguese
Authors: Barreto INGRID Ferreira , FREITAS ALESSANDRA DOCE DIAS
Published: November 2017

A presente pesquisa foi realizada na Comunidade Barreiras no município de Almeirim, Pará, tendo como objetivo realizar um levantamento etnobotânico em quintais agroflorestais da comunidade. Os informantes foram selecionados a partir da técnica bola de neve e a coleta de dados ocorreu a partir da aplicação de formulários semiestruturados, associados à técnica da turnê-guiada, realizada com os mantenedores dos quintais. Foram feitos registros fotográficos das plantas e coletado material botânico para realizar a identificação. Nos 30 quintais foram relacionadas 84 espécies, pertencentes a 42 famílias. As categorias etnobotânicas identificadas foram: alimentícias, medicinais, ornamentais e utensílios. Estes dados constituem um indicativo de que o uso das plantas dos quintais representa uma alternativa para a manutenção da qualidade de vida das famílias e para a conservação da diversidade local.
Authors: Soliani Rodrigo Duarte
Published: November 2017

Os custos com transporte vêm se mostrando cada vez mais representativos no que se refere ao comprometimento da receita do produtor. Diante desse cenário, a utilização de alternativas ao transporte rodoviário, pode minimizar substancialmente os custos logísticos. O artigo teve por objetivo apresentar o atual cenário da logística de exportação de açúcar no Estado de São Paulo, com foco no transporte, caracterizando os modais e suas respectivas infraestruturas disponíveis ao transporte com destino ao Porto de Santos, comparando-o aos sistemas logísticos chinês, europeu e americano, buscando identificar práticas e projetos em que o setor sucroalcooleiro possa inspirar-se na busca por soluções para a redução do custo operacional, visando o ganho de competitividade frente ao mercado internacional. Quanto à classificação desta pesquisa, do ponto de vista de sua natureza é aplicada e a técnica adotada é a pesquisa bibliográfica, onde utilizou-se teses, dissertações, artigos, jornais e revistas do setor de modo a justificar a importância da temática tratada. A análise deixa claro que diante da infraestrutura atual há possibilidade de redução representativa dos custos com transporte.
PROTECTIVE EFFECTS OF CISTANCHES HERBA AQUEOUS EXTRACT ON CISPLATIN-INDUCED PREMATURE OVARIAN FAILURE IN MICE
Authors: Pan Pengyu , Wang Ying , Leng Xue , Deng Jinfang , Wang Chun
Published: November 2017

Background: Chemotherapeutic treatment of premenopausal women has been linked to premature ovarian failure (POF). Cistanches Herba (CH) is a commonly used male impotence and female infertility treatment in China; however, whether CH protects ovaries from chemotherapeutic drug-induced POF remains unclear. In this study, we investigated the protective effects of CH in a mouse model of chemotherapeutic drug-induced POF.

Materials and Methods: We administered low- and high-concentration CH to cisplatin-induced POF mice for 2 weeks and determined body and ovarian weights, as well as serum follicle-stimulating hormone (FSH) and estradiol concentrations, to evaluate ovarian function. In addition, we evaluated the protective mechanisms of CH by detecting the levels of apoptosis-related proteins and evaluating markers of mitochondrial function.

Results: In POF mice, we observed reduced body and ovarian weights; elevated serum FSH and attenuated estradiol concentrations; apoptosis of ovarian granulosa with concomitant changes in apoptosis-related proteins (including caspase-3, poly adenosine diphosphate-ribose polymerase, Bcl-2, and Bax); and mitochondrial dysfunction, such as a reduction in mitochondrial numbers, destruction of ultrastructural morphology, decrease in ATPase activity, and decreases in mitochondrial membrane potential and mitofusin-2 (a mitochondria dynamin-like GTPase). Significantly, CH reversed, to an extent, functional and morphologic injuries and ovarian tissue apoptosis by up-regulating the level of Mfn2 and the ratio of Bcl-2/Bax. Furthermore, CH reduced cisplatin-induced mitochondrial dysfunction in ovarian tissues.

Conclusion: The present findings showed that CH inhibited cisplatin-induced POF through interactions between Mfn2 and Bcl-2/Bax proteins and, possibly, by up-regulation of Mfn2 expression. Ultimately, CH protects ovarian tissues from cisplatin-induced apoptosis.
ANTI-DIABETIC AND ANTIOXIDANT POTENTIALS OF AQUEOUS EXTRACT OF EUCALYPTUS GLOBULUS IN EXPERIMENTALLY-INDUCED DIABETIC RATS
Authors: Saka W.A , Akhigbe R.E , Ajayi A.F , Ajayi L.O , Nwabuzor O.E
Published: November 2017

Background: Evaluation of the medicinal uses of plants remains a growing field of research. This study investigated

the effects of Eucalyptus globules on alloxan -induced diabetic rats.

Materials and Methods: Thirty male albino rats were randomized into 5 groups (n=6). Group A served as the control

and was maintained on standard rat chow and water ad’libitum. Diabetes was induced in Group C, D and E animals by

intraperitoneal administration of alloxan monohydrate (150 mg/kg). Groups B and D were orally administered with

aqueous extract of Eucalyptus globulus at a dose of 150 mg/kg per oral daily for 4 weeks, while group E received

glibenclamide at a dose of 0.6 mg/kg orally in addition. Fasting plasma glucose, antioxidant status (catalase and

xanthine), malondialdehyde (MDA), liver function enzymes (AST and ALT) and bicarbonate ion (HC03

-) were

assessed after 4 weeks.

Results: Aqueous extract of Eucalyptus globulus leaves significantly reduced fasting plasma glucose level, MDA,

HC03

-, and liver enzymes (P
BIOACTIVITY OF ESSENTIAL OILS FROM MEDICINAL PLANTS OF CAMEROON AND THEIR COMBINATION AGAINST INFANT DIARRHEA INDUCED BY BACTERIA
Authors: Ascension Nyegue Maximilienne , Del Florence Moni Ndedi Esther , Florentine Ndoyé-Foe , Fronçois-Xavier Etoa , Menut Chantal
Published: November 2017

Background: In Cameroon, one of the most common childhood illnesses after malaria is diarrhea, which generally has

a bacterial origin. In rural areas, plant utilization is often one of the first ways of treatment though, with no scientific

bases. Therefore, the aim of this work was to evaluate the antibacterial activities of nine essential oils (EOs) of

Cameroonian plants and their combinations against some strains responsible for diarrhea.

Material and Methods: To determine the bacterial species generally involved in childhood diarrheal infections, a

retrospective study was done. The EOs of Eucalyptus globulus, Cymbopogon citratus, Xylopia aethiopica, Thymus

vulgaris, Ocimum canum, Cananga odorata, Citrus medica, Citrus paradisi and Citrus reticulata were screened against

the most incriminated bacterial species using the spot-on-agar test and microdilution methods. Some of the EOs with

good antibacterial activity were analyzed by Gas Chromatography and Gas Chromatography/Mass Spectrometry.

According to their composition, Thymus vulgaris and Eucalyptus globulus EOs were combined with that of

Cymbopogon citratus using the ratios 2/1; 1/1; 1/2 (w/w) and tested against on bacterial growth.

Results: The retrospective study showed that 10.8% of infant diarrhea was caused by Escherichia coli, Salmonella

typhimurium and Salmonella paratyphimurium. The Minimum inhibition Concentrations (MIC) of single EOs was

between 0.78 and 25 mg/mL which were observed to be greater than those of their combinations which ranged between

0.195 and 6.52 mg/mL. The active essential oils contained mainly hydrocarbonated and oxygenated monoterpens.

Conclusion: The good antibacterial effects of two Thymus combinations Th1 and Th2 observed on Salmonella

typhimurium and Salmonella paratyphimurium suggest their used in aromatherapy to cure bacterial diarrhea.
ANTIOXIDANT, ANTI-INFLAMMATORY AND ANTI-NOCICEPTIVE PROPERTIES OF HYDRO-METHANOL EXTRACT OF EREMOMASTAX SPECIOSA (HOCHST.) CUFOD LEAF
Authors: Onoja Samuel O. , Eke Chinemerem , Ejiofo Emmanuel , Madubuike Kelechi G. , Ezeja Maxwell I. , Omeh Yusuf N. , Anaga Aruh O.
Published: November 2017

Background: Eremomastax speciosa (Hochst.) Cufod is a perennial herb found in Africa along the rainforest zone and occurs as weed. It is cultivated in Cameroon and Akwa-Ibom in Nigeria due to its medicinal values. This study investigated the antioxidant, anti-inflammatory and antinociceptive properties of hydromethanol extract of Eremomastax speciosa (Hochst.) Cufod leaf in rat model.

Materials and Methods: The plant material was extracted using cold maceration method in 80% hydromethanol. The acute oral toxicity test was performed using Up and Down method with limit dose of 2000 mg/kg. The in vitro antioxidant property was evaluated with 2,2-diphenyl-1-picrylhydrazyl and ferric reducing antioxidant power photometric assays. The anti-inflammatory potential was investigated in egg-albumin and carrageenan induced paw edema models while the antinociceptive activity was determined using acetic acid induced writhing reflex and tail immersion tests at the doses of 50, 100 and 200 mg/kg. The negative control group (group A) received distilled water (vehicle) at 5 ml/kg while acetyl salicylic acid (200 mg/kg) was used as the reference drug for the anti-inflammatory models and acetic acid induced writhing reflex model while pentazocine (5 mg/kg) was used as the reference drug for tail immersion test.

Results: The LD50 of the extract was greater than 2000 mg/kg. The extract (25 to 400 μg/ml) demonstrated potent antioxidant activities in both the 2,2-diphenyl-1-picrylhydrazyl and ferric reducing antioxidant power assays. The E. speciosa extract caused significant (P < 0.05) anti-inflammatory and antinociceptive activities in the extract treated groups when compared to rats that received distilled water. The optimal activities of the extract were produced at the dose of 100 mg/kg.

Conclusion: The study supports the folkloric use of Eremomastax speciosa leaf in the management of pain and inflammatory conditions in traditional medicine.
EFFECT OF THEVETIA PERUVIANA ON MURINE-INDUCED OBESITY
Authors: Pérez-García Ma Dolores , Romero-Cerecero Ofelia , Zamilpa Alejandro , Román-Ramos Rubén , Tortoriello Jaime
Published: November 2017

Background: Obesity is considered a multifactorial disease that has importantly increased the development of chronic degenerative diseases. Drugs available for treating obesity have the inconvenience of producing side effects of importance. In Mexican traditional medicine, the seeds of Thevetia peruviana have been widely employed for weight reduction.

Materials and Methods: The effect produced by different extracts of T. peruviana on MonoSodium Glutamate (MSG)-induced obesity in mice was evaluated. A chemical analysis oriented toward the identification of the chemical compounds contained in the active extract was carried out.

Results: Oral administration of the hexanic extract of T. peruviana (for 7 weeks) was capable of diminishing weight gain by up to 24.1% in the mice without observing the development of resistance to insulin. Median lethal dose of the hexanic and Ethyl Acetate (EtOAc) extracts was >2 g/kg. By utilizing bio-assay guided fractionation, eight secondary metabolites were purified and characterized.

Conclusion: The hexanic extract obtained from Thevetia peruviana seeds was capable of reducing weight gain in mice with induced obesity. In addition, this extract showed good response to the glucose tolerance test, was able to avoid the development of insulin resistance, and also substantially increased serum adiponectin levels. Eight low-polarity compounds were identified in the active fraction. This species could be considered for ongoing investigation as a potential option to reduce obesity