bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengetahuan tentang penyakit hepatitis B dengan perilaku pemeriksaan HBsAg pada ibu hamil di Puskesmas
Authors: Surmiasih S , Aprida Hernovi , Hardono Hardono , Putri Riska Hediya
Published: September 2020

Hepatitis B is a liver disease that can be chronic and can cause cirrhosis. Pregnant women infected with hepatitis B can transmit the infection vertically to the fetus they were carrying during labor and immediately after delivery in Indonesia, there were 1,017,290 people with hepatitis out of this number 506,576 were female patients. Risks obtained by pregnant women who are infected with HBV can include abortion, preterm labor, and bleeding. The purpose of this study was to determine the level of knowledge about hepatitis B and HBsAg examination behavior in pregnant women at Puskesmas Kasui Kabupaten Way Kanan. The type of this research was quantitative descriptive, with a cross-sectional approach. Total sampling. Analysis of using descriptive statistical tests. The results showed a level of knowledge about hepatitis B with less understanding of 40 percent and HBsAg examination behavior in pregnant women by 54.3 percent. It is expected that the results of this study can improve services to pregnant women in providing counseling about hepatitis B and HBsAg examination for early detection by conducting HBsAg Rapid Diagnostic Test (RDT) so that they can handle early to prevent transmission of the virus from mother to baby.
Pembuatan Disinfektan dari Bahan Alami untuk Meminimalisir Penularan Covid-19
Authors: Budiman Budiman , Arisman Anugrah Yusuf , Sulfidar Sulfidar , Arsyad Muhammad
Published: September 2020

This research was conducted to produce disinfectants made from natural aims to reduce Covid-19 transmission for people who are less able. Where in minimizing the spread of one of them washing hands using disinfectants. The results of the research are betel leaf, lemon, and water can be made in preparation as a disinfectant. This research was carried out through various sources including books, the internet, and journals and research by others. It is expected that the results of this study can provide education to the public so that they maintain better health and personal hygiene to reduce the increase in the spread of Covid-19, especially in Indonesia.
Sikap dan dukungan suami dengan pemakaian Metode Kontrasepsi Jangka Panjang (MKJP) aseptor KB baru
Authors: Yuliarti Elis , Komalasari Komalasari , Fitriana Fitriana , Veronica Septika Yani
Published: September 2020

Jumlah penduduk dunia terus tumbuh dan telah mencapai 7,2 milyar pada tahun 2013, demikian juga di Indonesia. MKJP Tujuan dari penelitian ini untuk mengetahui Hubungan Sikap dan Dukungan Suami Dengan Pemakaianan MKJP Aseptor KB Baru di Puskesmas Tanjung Agung Baturaja Tahun 2020. Jenis penelitian kuantitatif rancangan penelitian analitik dengan pendekatan crossectional. Populasi yaitu seluruh akseptor KB baru di wilayah kerja Puskesmas Tanjung Agung Baturaja yaitu dari data bulan Januari-Desember tahun 2019 sebanyak 510. Pengambilan sampel dengan menggunakan cluster sampling. Analisis data yang menggunakan uji chi square. Hasil analisis dan pengolahan data didapatkan ada hubungan sikap dengan pemakaian  MKJP Aseptor KB Baru diperoleh p-value 0,003 (kurang dari 0.05) dan tidak ada hubungan dukungan suami dengan pemakaian MKJP Aseptor KB Baru diperoleh p-value 0,964 (lebih dari 0.05). Hasil penelitian ini diharapkan dapat menambah pengetahuan dan pemahaman ibu usia reproduksi tentang metode kontrasepsi khususnya pada kontrasepsi jangka panjang sehingga lebih memantapkan mereka dalam memilih MKJP.Abstract: The world population continues to grow and has reached 7.2 billion in 2013, as well as in Indonesia.LTCM The research objective was to determine the Relationship Between Husband's Attitude and Support of  Using  LTCM on Primary Birth Control Acceptor at Community Health Center Tanjung Agung Baturaja in 2020. The type is a quantitative analytical research design with a cross-sectional approach. The population was all primary birth control acceptors in the working area of Community Health Center TanjungAgungBaturaja, from January up to December 2019 as much as 510. In taking the sample is using cluster sampling. The data analysis uses the chi-square test. The results of analysis and processing data show that there is a relationship between attitude and the use of LTCM on Primary Birth Control Acceptorwith p-value 0.003 (less than 0.05) and there is no relationship between husband's support and the use of LTCM on Primary Birth Control Acceptorwith p-value 0.964 (more than 0.05). It is expected that the results of this research increase the knowledge and understanding of reproductive-age mothers about contraceptive methods, especially in long-term contraception so that they are more stable in choosing the LTCM.
Literature Review: Keefektifan Pemberian Obat Nyeri di Instalasi Gawat Darurat
Authors: Hapsari Ayu Fitriana , Sudaryanto Agus
Published: September 2020

Background. Nyeri akut adalah keluhan utama yang paling umum terlihat di gawat darurat (ED), nyeri sering tidak dirawat dengan baik di UGD. Pasien yang datang ke UGD sering membutuhkan perawatan tepat waktu, berpotensi termasuk pemberian obat untuk menghilangkan gejala mereka, seperti rasa sakit. Obat yang diprakarsai perawat telah menjadi salah satu strategi terpenting yang diterapkan di UGD untuk memfasilitasi perawatan tepat waktu. Objectives. Untuk membahas literature yang telah ada saat ini tentang keefektifan perawat memberian obat nyeri di UGD. Methods. Metode yang digunakan dalam penelitian ini adalah metode studi literature review dengan menganalisis dari literature-literature review yang telah dipilih dan ditelaah dari beberapa sumber sehingga menjadi bahasan baru. Jurnal yang dibahas dalam topik bahasan ini dengan kata kunci yaitu: pemberian obat di Unit Gawat Darurat. Penulis melakukan penelusuran jurnal pada bulan Juli 2020, diperoleh dengan pencarian menggunakan Google scholar, Proquest, Pubmed. Kata kunci analgesia, gawat darurat, penelitian layanan kesehatan, regresi linier, pemodelan multivariat, perawatan keperawatan, nyeri. Result. Obat yang diprakarsai perawat adalah salbutamol untuk kondisi pernapasan dan analgesia untuk kondisi yang memungkinkan pasien menerima obat lebih cepat setengah jam dibandingkan dengan mereka yang tidak memiliki obat yang diprakarsai perawat. Intervensi tidak berpengaruh pada efek samping, waktu tunggu dokter dan lama tinggal. Analgesia terkait perawat dikaitkan dengan peningkatan kemungkinan menerima analgesia, mencapai pengurangan nyeri yang relevan secara klinis, dan kepuasan pasien yang lebih baik.
Gaya hidup penderita diabetes mellitus Tipe 2 pada masyarakat di daerah perkotaan
Authors: Febriyan Heironimus Billy
Published: September 2020

Diabetes Mellitus Type 2 is a disease characterized by high glucose levels in the blood exceed the standard value. The condition causes the disruption of the function of organs, causing all sorts of problems, among others such as eye disorders, heart, healing wounds, and stroke. Diabetes mellitus type 2 has some risk factors such as gender, age, family history, diabetes, obesity, hypertension, dyslipidemia, less activity, fat and carbohydrate intake high. The residence also can be a risk factor for type 2 diabetes mellitus where urban areas are associated with a change in lifestyle and dietary habits compared with the countryside. It became one of the causes of the increase in type 2 diabetes mellitus in urban areas. Conclusion It was found that type 2 diabetes mellitus is very influential, especially in decreased quality of life, especially in urban areas.
Responsibility Of The Notary Department As A Consequence Of Secret Of The Minutes Deed Misuse By Its Employees
Authors: Kurniawan David Ayank , Purnawan Amin
Published: September 2020

The purpose of this study is to identify and analyze: 1) The importance of the notary's obligation to safeguard the confidentiality of the contents of any particular act as referred to in Article 16 paragraph 1 of the letter (f) of Act No. 2 of 2014 Regarding Change of Law of 30 of 2004 About the Notary Department. 2). It is the responsibility of the Notary department for the abuse of confidentiality by millions of employees.This study is a type of normative juridical research, using a legislative and conceptual approach to Data collection derived from primary and secondary data, using interview methods and library studies. Data analysis techniques using qualitative data analysis.The result of the research is 1).The importance of the Notary's obligation to safeguard the confidentiality of the contents of the deed, particularly in the matter of Article 16 paragraph 1 letter (f) of Act No. 2 of 2014 About the Amendment of Act No. 30 of 2004 About the Notary Department is to keep everything confidential. and any evidence obtained for the making of the deed in accordance with the oath / appointment of the department. 2). The responsibility of the notary office is due to the misuse of confidentiality by the employees although in this case the notary does not commit a direct offense, because in one of the principles of civil liability there is a principle of absolute responsibility, whereby the person commits an error indirectly (due to negligence or negligence) heart) can be held responsible for the loss suffered by someone.Keywords: Notaries; Responsibilities; Minutes Deed.
Shape and Volumetric Differences in the Corpus Callosum between Patients with Major Depressive Disorder and Healthy Controls
Authors: Lee Sekwang , Pyun Sung-Bom , Choi Kwan Woo , Tae Woo-Suk
Published: September 2020

Objective This study aimed to investigate the morphometric differences in the corpus callosum between patients with major depressive disorder (MDD) and healthy controls and analyze their relationship to gray matter changes.Methods Twenty female MDD patients and 21 healthy controls (HCs) were included in the study. To identify the difference in the regional gray matter concentration (GMC), VBM was performed with T1 magnetic resonance imaging. The shape analysis of the corpus callosum was processed. Diffusion tensor imaging (DTI) fiber-tracking was performed to identify the regional tract pathways in the damaged corpus callosal areas.Results In the shape analysis, regional shape contractions in the rostrum and splenium were found in the MDD patients. VBM analysis showed a significantly lower white matter concentration in the genu and splenium, and a significantly lower GMC in the frontal, limbic, insular, and temporal regions of the MDD patients compared to the HCs. In DTI fiber-tracking, the fibers crossing the damaged areas of the genu, rostrum, and splenium were anatomically connected to the areas of lower GMC in MDD patients.Conclusion These findings support that major depressive disorder may be due to disturbances in multiple neuronal circuits, especially those associated with the corpus callosum.
El Eros amenazado: cuerpos y territorios ganados en Un mundo huérfano de Giuseppe Caputo
Authors: Mora Moreno Sergio Antonio , Sánchez Noguera Jorge Mario
Published: September 2020

Este artículo indaga el lugar que se le otorga a los cuerpos diversos y las luchas que estos enfrentan en Un mundo huérfano (2016) de Giuseppe Caputo. En la obra, se pone de manifiesto un tropo que ha atravesado la historia de la literatura: la relación entre Eros y Tánatos. Sin embargo, aquí la muerte no es producto del amor fatal entre los amantes, sino que esta es infligida por quienes consideran que ciertos cuerpos, el Eros que se produce entre estos, no son lícitos, por tanto, deben ser borrados del territorio. La novela enuncia la orfandad y precariedad en la que se encuentran los individuos que no solo están marginalizados por romper la matriz patriarcal y heteronormativa, sino que se encuentran en los márgenes de las ciudades. No obstante, el Eros, posibilita la creación de un territorio propio, en el que estos cuerpos se resisten al poder soberano.
Corte y conceptualismo en La Filial (2013) de Matías Celedón
Authors: Reyes Sebastian
Published: September 2020

La “novela” La Filial (2013) de Matías Celedón es un texto híbrido por su materialidad y estrategias conceptuales de escritura. El artículo destaca posibles genealogías literarias de esta obra, relacionadas con la poesía visual y algunas formas de conceptualismo en la literatura. La Filial se analiza a través de la noción “corte”, estudiando cómo el texto se escribe a partir de disrupciones en el tiempo y el espacio de la escritura, los que se pueden asociar a estados de excepción, y a formas de alienación y extrañamiento. La heterogeneidad de códigos y registros, el minimalismo de la objetualidad, su lenguaje ambiguo y figurativo, son algunas de las características que hacen de La Filial un artefacto a través del cual se puede cuestionar la manera en que construimos la memoria y la historia.
Ant Colony Optimization for Prediction of Compound-Protein Interactions
Authors: Purnajaya Akhmad Rezki
Published: September 2020

The prediction of Compound-Protein Interactions (CPI) is an essential step in drug-target analysis for developing new drugs. Therefore, it needs a good incentive to develop a faster and more effective method to predicting the interaction between compound and protein. Predicting the unobserved link of CPI can be done with Ant Colony Optimization for Link Prediction (ACO_LP) algorithms. Each ant selects its path according to the pheromone value and the heuristic information in the link. The path passed by the ant is evaluated and the pheromone information on each link is updated according to the quality of the path. The pheromones on each link are used as the final value of similarity between nodes. The ACO_LP are tested on benchmark CPI data: Nuclear Receptor, G-Protein Coupled Receptor (GPCR), Ion Channel, and Enzyme. Result show that the accuracy values for Nuclear Receptor, GPCR, Ion Channel, and Enzyme dataset are 0.62, 0.62, 0.74, and 0.79 respectively. The results indicate that ACO_LP has good accuracy for prediction of CPI.
Pengaruh Budaya Terhadap Actual Use Digital Payment System Pada Pelaku UMKM di Kota Batam
Authors: Pintubipar Saragih Saut , Nopriadi Nopriadi
Published: September 2020

Digital payment gateway yang digunakan masyarakat Kota Batam sangat beragam. Sistem pembayaran digital tersebut diantaranya adalah internet banking, mobile banking, mobile application payment, dan juga masih ada yang menggunakan electronic data capture. Jumlah pengguna yang paling banyak adalah penggun sistem pembayaran digital berbasis mobile banking dan internet banking yang mencapai hamper 80% dari total responden yang ada. Pelaku umkm di Kota Batam sudah mengenal sistem pembayaran digital dengan baik dan juga sudah menggunakan dalam rentang waktu yang cukup lama yaitu rata-rata tigas tahun. Budaya di Kota Batam ditinjau dalam hal teknologi informasi secara keseluruhan sudah baik dimana hasil olah data menunjukan bahwa 50% pelaku usaha sudah menerima sistem pembayaran digital untuk mendukung kegiatan usaha mereka. Hasil penelitian ini menyimpulka bahwa budaya memberikan pengaruh positif terhadap actual use (penggunaan) sistem pembayaran digital. Nilai signifikansi pada hasil pengolahan data kuesioner menunjukan bahwa variable budaya pelaku UMKM di Kota Batam tidak dominan terhadap variable actual use karena pada nilai R square pada table anova menghasilkan nilai 0,509. Namun secara khusus pada uji regresi linier dan juga uji hipotesis menghasilkan kesimpulan bahwa budaya pelaku UMKM di Kota Batam mempengaruhi penggunaan sistem pembayaran digital.
Prototipe Green Internet Technology Guna Mendukung Infrastruktur Desa Pintar
Authors: Nurchim Nurchim , Pradana Afu Ichsan
Published: September 2020

Internet menjadi salah satu infrastuktur pendukung keberhasilan implementasi desa pintar. Di Indonesia, banyak pemerintah desa yang sudah menyediakan access point internet di wilayah desa untuk dapat dimanfaatkan secara publik. Namun, pemasangan access point ini belum dapat menjangkau seluruh wilayah desa dikarenakan kendala geografis dan ketersediaan listrik. Penelitian ini bertujuan untuk membuat prototipe access point internet dengan tenaga surya atau yang dikenal dengan istilah Green Internet Technology. Pembuatan prototipe dilakukan dengan pendekatan Design Based Research (DBR) yang terdiri enam langkah meliputi (1) focus, (2) understand, (3) define, (4) conceive, (5) build dan (6) test. Prototipe Green Internet Technology memiliki 3 bagian utama meliputi (1) sistem tenaga surya, (2) sistem access point internet dan (3) sistem monitoring tenaga surya. Hasil pengujian di lingkungan nyata bahwa sistem tenaga surya dan access point internet dapat bekerja selama 24 jam setiap hari. Namun ke depan, pada sistem monitoring tenaga surya perlu dilakukan pengkajian kembali khususnya dalam kestabilan kinerja perangkat sensor arus dan tegangan.
MultiClass Decision Forest Machine Learning Artificial Intelligence
Authors: Siswoyo Bambang
Published: September 2020

Kecerdasan buatan merupakan solusi yang terbaik dalam menangai berbagai bidang. Algoritma Multi Class Decesion Forest Machine Learning yang merupakan bagian dari kecerdasan buatan adalah bidang yang menarik untuk diterapkan dalam bidang perbankan. Penelitian ini dikembangkan untuk membangun model yang dapat memprediksi dan mengevaluasi kebangkrutan industri perbankan. Variabel prediktor adalah rasio keuangan yang didapatkan dari publikasi situs http://www.idx.co.id. Modeling machine learning dengan enam variabel, dimana lima variabel sebagai input dan satu variabel sebagai target. Secara keseluruhan, Multi Class Decistion Forest Machine Learning mampu melatih data hubungan input-output dan perilaku pemodelan dengan baik, nilai accuracy 92%, nilai precision 92% dan nilai under area curve 90%.
Aplikasi Edukasi Kuis Matematika Untuk Tingkat Sekolah Menengah Pertama Berbasis Android
Authors: Yulia Yulia , Karnadi Very
Published: September 2020

Mathematics is a science that is widely used in everyday life such as used in trade transactions, carpentry, and so on. But until now many people think that mathematics is a subject that is considered difficult and difficult to understand, especially for junior high school students. Though mathematics itself has been taught starting from the level of childhood and elementary school. Because learning methods still use conventional methods such as the ability to write and count, this is what makes students feel bored because moreover some students do not like these math subjects. Not only in terms of subjects and learning media is still conventional in nature that is only based on the book. For this reason, a learning media is created which is packaged in an android-based application by including elements of mathematics learning in it. The application that was designed was a junior high school level mathematics education quiz application, with the aim of training students 'ability to count, train their memory and increase students' interest in learning in mathematics.
Penerapan Algoritma Elephant Herding Optimization (EHO) pada Masalah Hybrid Flowshop Scheduling (HFS)
Authors: Kamsyakawuni Ahmad , Palupi Khurnia , Pradjaningsih Agustina
Published: September 2020

Industri menjadi salah satu motor penggerak perekonomian di Indonesia. Salah satu masalah yang dihadapi oleh perusahaan industri dalam proses produksi adalah menentukan jadwal produksi. Jadwal produksi yang tidak sesuai target yang ditentukan dapat menyebabkan kerugian pada perusahaan. Penjadwalan merupakan alokasi dari sumber daya untuk menjalankan sekumpulan pekerjaan dalam jangka waktu tertentu. Permasalahan yang diselesaikan pada artikel ini adalah hybrid flowshop scheduling (HFS), yang akan diterapkan pada perusahaan dibidang pembuatan roti. Solusi untuk menyelesaikan masalah HFS menggunakan algoritma elephant herding optimization (EHO). Agar perusahaan dapat menyelesaikan proses produksi dengan meminumkan total waktu proses yang dibutuhkan untuk menyelesaikan job (makespan) diperlukan penjadwalan yang efektif dengan memperhatikan jumlah mesin paralel. Hasil dari artikel ini adalah 9 job dan makepsan 11.270 detik menggunakan program MATLAB.
Sistem Informasi Peminjaman Laboratorium pada Cross-Platform dengan Metode Prototyping (Studi Kasus: Politeknik Caltex Riau)
Authors: Wijaya Leony Veronica , Ramadhani Shumaya Resty
Published: September 2020

The Laboratory information system is one of the information systems that was built by the BSTI of Polytechnic Caltex Riau to provide information about laboratory lending. This system is also being intended to the person who is in charge of approving laboratory lending such as the head of the laboratory, and laboratory assistant in case of monitoring some of the laboratories that are lent. However, the features provided by this information system are not enough to support the process of laboratory lending. Therefore, a mobile application with the quality of Cross-Platform was built, in other words, it can be used on iOS and Android platforms. One of the technologies that can be used to build a cross-platform application is the React Native. This application was built with a prototype method that is used to get more perspective points from users with interviews and can simplify the development of this application to be effective. This application was developed with Laravel, Firebase Authentication, and MySQL. Because there are several problems with the old system, an application that offers several solutions consists of avasisten instruktur laboratoriumbility in the lending laboratory, receiving legal paper of laboratory lending, and receiving notification were developed in this study. The main feature provided in this application is the evidence letter of laboratory lending that doesn’t have to be printed so that can reduce paper usage. As a result, 94.1% of respondents stated that this application’s features can run well and make it easy for college students to propose laboratory lending.
Pengujian Heuristic Pada Antarmuka Marketplace Desa Wisata (Studi Kasus: Guidehub.Id)
Authors: Pujastuti Eli , Fatkhurohman Agus
Published: September 2020

Ada 229 desa wisata yang saat ini sudah terbentuk di Yogyakarta. Desa wisata tersebut memiliki permasalahan yang beragam, salah satunya adalah pendapatan warga lokal yang tidak meningkat dikarenakan keterbatasan warga dalam mempromosikan desa wisatanya. Platform guidehub.id adalah startup yang membantu desa wisata mempromosikan paket wisata yang dimiliki. Pengguna guidehub.id adalah warga desa wisata. Keragaman latar belakang dari pengguna menuntut pembuatan antarmuka yang mudah digunakan. Kesalahan perancangan antarmuka akan berakibat pada pendapatan desa, Oleh karena itu, sebelum website digunakan oleh pengelola desa wisata, perlu adanya evaluasi terhadap website guidehub.id. Penelitian ini bermaksud mengevaluasi dengan cara mencari nilai severity rate untuk selanjutnya memberikan rekomendasi kepada pengembang website dengan metode usability heuristic. Metode yang digunakan untuk mengukur usability website adalah 8 Golden Rule dari Shneiderman. Hasilnya perbaikan antarmuka marketplace desa wisata (guidehub.id) cukup mayor. Terdapat 5 variabel yang memiliki severity rate tinggi yang artinya harus diperbaiki sebelum website diluncurkan yaitu pada variabel Strive for consistency, Offer informative feedback, Prevent Errors, Permit easy reversal of action dan Support internal locus of control. Rekomendasi untuk temuan yang ada adalah bahasa yang harus konsisten, perlu adanya pemberitahuan apakah user berhasil atau gagal login, sebaiknya ada penanganan error pada saat booking dan submit tour, sebaiknya data tetap ada ketika mengisi form dan ingin kembali ke halaman sebelumnya, dan seharusnya user memiliki control sepenuhnya ketika memilih menghapus tour namun mengurungkan niat untuk menghapus.
Hepatotoxicidade induzida por medicamento em um paciente ambulatorial: relato de caso
Authors: PRADO NÍLIA MARIA DE BRITO LIMA , MESSIAS GLADISTONE CORREIA , JUNIOR GENARIO OLIVEIRA SANTOS , PARANÁ RAYMUNDO
Published: September 2020

A hepatite induzida por drogas, também chamada hepatite tóxica ou DILI, representa cerca de 2% da hospitalização por casos de icterícia e o fígado está envolvido em 3-10% de todas as reações adversas a medicamentos (ADRs). Os casos de lesões hepáticas associadas ao uso de ibuprofeno são raros e a freqüência de hepatotoxicidade idiossincrática é pequena. Objetivo: Relatar um caso de lesão hepática induzida por ibuprofeno identificada em um ambulatório de média complexidade. Relato de caso: Paciente do sexo feminino, 48 anos, admitida em um Centro de Assistência Especializado em uma cidade da região sudoeste do estado da Bahia, referiu-se ao serviço de saúde para uma consulta com um ortopedista, reclamando dor intensa na coluna. Fez uso de ibuprofeno e dipirona sódica em caso de dor. Foi solicitado ao paciente no momento da avaliação clínica inicial, a realizalizaç testes de função hepática, com o objetivo de descartar lesões hepáticas anteriores. Após 15 dias de tratamento, o paciente voltou ao serviço, queixando-se de dor nas articulações nos membros superiores e edema em mão direita, colúria, acolia fecal, quadro álgico , insônia, astenia e prurido intenso, especialmente à noite. Marcadores virais e autoimunes negativos. Um ultrassom do abdômen total mostrou uma ligeira textura anormal do fígado, um cálculos biliares em movimento, sugerindo coledocolitíase. Aplicando RUCAM, a reação altamente provável. Conclusão: A lesão hepática mostrada pelo paciente tem uma forte relação causal com o uso de ibuprofeno.
Erros de prescrição de medicamentos: uma avaliação da prescrição na pediatria de um hospital escola
Authors: COSTA DAYANE BESERRA , MACEDO LUCIANA LUCENA ARANHA DE , SOUTO ROSA ÁGUIDA DONOSORA DE MELO , SANTOS ANA LUIZA DOS
Published: September 2020

A pesquisa objetivou analisar a qualidade das prescrições em pediatria com ênfase nos erros de prescrição. Trata-se de um estudo observacional, descritivo, transversal com delineamento retrospectivo. Foi realizado na Clínica Pediátrica de um hospital de ensino. As variáveis em estudo seguiram o que preconiza o Protocolo de Segurança na Prescrição, Uso e Administração de Medicamentos do Ministério da Saúde. Os dados foram armazenados, organizados e tratados estatisticamente com auxílio do programa SPSS versão 20. Foram analisadas 898 prescrições, contendo um total de 3858 itens, e estavam ausentes nas prescrições as seguintes variáveis analisadas: nome completo do usuário 2,7%, número do prontuário 61,5%, ala 1,2%, leito 80,5%, enfermaria 15,9%. A forma farmacêutica esteve ausente em 26,1%, a concentração do fármaco não foi especificada em 20,3% e o tempo de tratamento não foi evidenciado em 85,2% das prescrições avaliadas. O volume e o tipo do diluente não foram descritos em 12,8% e 7,4% respectivamente, assim como não foram especificadas nas prescrições em estudo a velocidade e o tempo de infusão em 96,6% e 79,3% respectivamente. A pesquisa realizada revela que a qualidade da prescrição do hospital em questão precisa de ajustes importantes em vários aspectos, principalmente no que diz respeito aos medicamentos.
Inspeção farmacêutica em dez bases descentralizadas do serviço de atendimento móvel de urgência (SAMU) no sudoeste do Paraná
Authors: Molinett Francieli
Published: September 2020

O armazenamento tem a função de garantir que as propriedades farmacológicas e físico-químicas dos medicamentos sejam preservadas durante a sua permanência na prateleira, ou onde quer que estes fiquem armazenados, até o momento da utilização pelo paciente. No SAMU-192 não é diferente, por esse motivo, o serviço de Farmácia do SAMU-192 do sudoeste do Paraná, através deste estudo, teve como objetivo a instauração da Inspeção Farmacêutica nas dez bases descentralizadas da região sudoeste do Paraná, monitorando o armazenamento destes no almoxarifado e nas ambulâncias. Além disso, avaliou-se através de analise documental, o resultado da instauração das inspeções realizadas no período de maio de 2016 a maio de 2017, onde os dados provenientes dos documentos produzidos nas inspeções foram tabulados em planilha Excel com auxílio de elementos da estatística descritiva obedecendo às questões do roteiro de inspeção. O estudo mostrou a importância da Assistência Farmacêutica no ambiente pré-hospitalar, já que foram encontrados problemas potenciais em relação a medicamentos como a presença de lotes vencidos no almoxarifado e nas maletas de medicamentos presentes nas ambulâncias. Mais estudos são necessários para nortear a atividade do profissional farmacêutico no ambiente pré-hospitalar, que é tão escasso de estudos tanto no Brasil, quanto em outros países.
Deprescription on oncological palliative care: an integrating review
Authors: Antonio Ana P. , Silva Maria B. , Souza Mariana F. , Barbosa Maria F.
Published: September 2020

Background: Patients on oncologic palliative care (OPC), due to diverse symptomatology and variable severity, tend to present polypharmacy that, although it seems justifiable in many cases, can pose health risks and negative consequences on patients’ quality of life. Thus, it is necessary to evaluate the presence of possible therapeutic futilities, guiding the process of deprescription, in which there is a reduction in the amount of medication after reviewing the treatment objectives and assessing risks and benefits. Aim: The objective of this study was to identify the main classes of drugs that are candidates for the deprescribing for OPC patients by reviewing the literatura of the last 8 years. Methods: The bibliographic search was performed in the Medline and LILACS databases. Inclusion criteria were articles published between 2010 and 2018, which dealt with the topic of deprescription in CPO. The publications were analyzed for Qualis and the level of scientific evidence, in order to identify the main drugs candidates for deprescription. Results: Twenty articles were evaluated, being only 4 randomized clinical trials (RCTs), with level II of scientific evidence. Among the classes of drugs that are candidates for deprescription, the following stand out: statins (20.37%) and antihypertensives (20.07%). ECRs that corroborate with scientific evidence of quality need to be developed for guidelines that make it possible to prescribe, especially for the population in CPO. Conclusion: We highlight the importance of the use of tools to identify inappropriate medicines, and the use of medication conciliation as a means of identifying them, as well as pharmacotherapeutic follow-up.
Interventions performed by clinical pharmacist in the renal transplant ambulatory care
Authors: Gnatta Diego , Keitel Elizete , Heineck Isabela
Published: September 2020

Introduction: The development of new immuno-suppressant agents and other supporting medications has increased the complexity of medical regimes. Therefore, potential drug interactions, adverse reactions and costs may jeopardize a successful outcome. Although pharmacists have been involved in the care of patients after transplants, only a few kidney transplant teams can count with dedicated pharmaceutical services. Objective: The goal of this study was to describe the pharmaceutical interventions performed to improve treatment outcomes of patients who underwent kidney transplantation. Methods: This study was a randomized clinical trial and was carried out in a specialized transplant hospital in southern Brazil. The clinical pharmacist followed up 64 patients during a period of 12 months and performed interventions when identifying a drug related problem. The pharmaceutical interventions were categorized as “significant”, “very significant” or “extremely significant”. Medication-related negative outcomes were classified in relation to their effectiveness, safety and necessity. Results: Two hundred and twenty-six (226) pharmaceutical interventions were performed, with a mean of 3.25 ± 2.37 per patient. Among them, 159 (70.4%) were patient-oriented, and 67 (29.6%) were health teamoriented. Thirty eight percent were classified as very significant. Frequent pharmaceutical interventions performed were to suggest the reduction of immuno-suppressant doses to the physicians, educate patients with post-transplant diabetes mellitus or in case of skipping doses. One hundred and fourteen (114) medication-related negative outcomes were identified, 43% related to effectiveness, 36% to safety and 21% to necessity. The number of acute rejection confirmed by biopsy was 33 (51.6%). The free survival of acute rejection was 59.4% in the first month, 53.1% in the third month and 48.3% in 12 months. Conclusions: The pharmacist has an important role in the ambulatory care of kidney transplant, identifying problems and acting as a major player towards the reduction of medication-related negative outcomes.
Prevention of medication errors: a lot to be done in Brazil!
Authors: Rosa Mario B.
Published: September 2020

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Evaluation of a semi-structured model for the medication therapy management record in the hospital setting
Authors: Ferreira Luna E. , Azevedo Elaine A. , Falcão Marceli C. , Junior Nelson C. , Nascimento Yone A.
Published: September 2020

Introduction: The record of the activities performed by the health professional should compose the patient’s medical record, whose fundamental role is communication. One way to make registration easier is to create semi-structured models. Objective: To evaluate the applicability and reproducibility of a semi-structured model for the medication therapy management record in hospitals. Methods: A convenience sampling of fifteen clinical pharmacists working in public hospitals in Minas Gerais was used. The participants received the semi-structured model for medical record and detailed report of two simulated clinical cases. The records made by each participant were compared to a standard record - template and the verification items were evaluated and categorized into: 1- compliant, 2- partially compliant, and 3- non-compliant. Participants also answered an electronic questionnaire with questions related to clinical experience and training. The main variable evaluated was the compliance percentage, considering the total of items evaluated. And for all variables under study, absolute and relative frequency were determined. The influence of the participants’ individual characteristics was univariate analyzed. Results: Most of the group (58%) had been graduated in Pharmacy for over ten years and most (83%) reported having been trained in the clinical area. The characteristics of the participants did not affect the results obtained. The overall compliance percentage showed a good performance of pharmacists using this model (76%) and most participants considered the model to be highly applicable / useful (75%). Conclusion: The high percentage of compliance achieved demonstrates that the semi-structured medical record model developed in this study was considered applicable by most participants, who also had a good performance in its use, and may be a starting point for other pharmacists and services to develop their own models, adapted to the reality of each service.
Pharmaceutical actuation in intensive care units: contributions to rational use of drugs
Authors: Maciel Eduarda C. , Borges Renan P. , Portela Áquila S.
Published: September 2020

Objective: Evaluate the performance of the clinical pharmacist in Adult Intensive Care Units of a special-sized hospital, wherein pharmacotherapeutic follow-up is the main activity developed by the pharmacist residing in intensive care. Methods: This is an observational, cross-sectional study with a quantitative approach, carried out in Adult Intensive Care Units, from March to June 2018. Data were collected from the Clinical Pharmacy Service, by means of already established indicators. Results: During the study period, 958 patients were admitted and 664 were included in the study. Regarding the place of hospitalization, 57% of the patients included in the study were hospitalized in the Post-operative Intensive Care Unit and 43% in the Clinical Intensive Care Unit. The suggested interventions were well accepted (99.6%), and in the clinical intensive care unit, the number of interventions performed and the cost saving were higher in all months of the study. The main interventions were drugs inclusion / withdrawal, dose reduction, infusion time and dilution. Of the interventions accepted, 25% generated cost savings, saving R $ 163,656.40 in total, and the types of interventions related to the most frequent cost saving were withdrawal of the drug (58.5%), dose reduction (32.6%) and change of pharmaceutical formula (3.0%). Conclusion: The performance of the clinical pharmacist in intensive care units was well accepted by the medical team. The various possibilities of interventions contribute to rational use of drugs and, in addition, some of these pharmaceutical interventions have a direct impact on cost savings.
The Effects Of Adult Ageing And Culture On Theory Of Mind
Authors: phillips louise , Lawrie Louisa , Schaefer Alexandre , Yong Min Hooi
Published: September 2020

Older adults tend to have poorer mental state understanding (Theory of Mind, ToM) than their younger counterparts, including in both Western and Asian cultures. The current study aimed to directly investigate whether there are any cultural differences in the pattern of age effects on ToM tasks. Given evidence of cultural differences in the development of ToM across childhood, we predicted that older Asian adults would find the mental state tasks particularly resource-demanding. We used two ToM tests which made differing demands on updating multiple mental states (the false belief task) and applying social rules to mental state processing (the faux pas task). We also looked at the role of education, socioeconomic status, individualism versus collectivism and working memory (WM). A total of 298 participants from UK and Malaysia completed faux pas, false belief, and WM tasks. Results showed that interacting effects of age and culture were evident in faux pas detection, some aspects of false belief reasoning, and WM tasks, with older Malaysian participants performing poorly compared to the other groups. We also found that WM fully mediated age differences in ToM in the Malaysian sample. High levels of individualism were associated with poorer faux pas detection, but education and socioeconomic status did not explain additional variance in the ToM tasks. This pattern of results may reflect generational changes in the familiarity and cognitive load of explicit mental state attribution, along with cultural differences in the pace and nature of cognitive ageing.
The platelet endothelial cell adhesion molecule PECAM1 is differentially expressed in non-small cell lung cancer.
Authors: Mamoor Shahan
Published: September 2020

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1, 2). We mined published microarray data (3, 4) to discover genes associated with NSCLC tumors. We identified significant differential expression of the platelet endothelial cell adhesion molecule PECAM1 (5) in primary tumors from patients with NSCLC. PECAM1 may be of relevance to the initiation, progression or maintenance of non-small cell lung cancers.
Melihat Freire Bekerja di Kampus Kita; Telaah Reflektif-Kritis Buku Siti Murtiningsih “Pendidikan; Alat Perlawanan”
Authors: Nur Askar
Published: September 2020

Penelitian ini menjelaskan tentang korelasi antara buku Siti Murtiningsih dengan kondisi kampus atau perguruan tinggi. Penilitian ini menggunakan metode studi pustaka dan reflektif kritis. Hasil penelitian menunjukkan bahwa terdapat beberapa hal yang menyebabkan perguruan tinggi dewasa ini tidak mengedepankan unsur pembebasan terhadap peserta didik dalam proses pembelajaran.
Membrane-Electrode Assemblies for Flow-Electrode Capacitive Deionization
Authors: Wessling Matthias
Published: September 2020

Scale-up of flow-electrode capacitive deionization is hindered due to the reliance on thick brittle graphite current collectors. Inspired by developments of electrochemical technologies we present the use of flexible membrane electrode assemblies (MEA) to solve these limitations. We tested different carbon-fiber fabrics as current collectorsand laminated them successfully with ion-exchange membranes. The use of thinner ion-exchange membranes is now possible due to the reinforcement with the carbon fiber fabric.Desalination experiments reveal that a MEA setup can achieve salt transfer rates equal to standard setups. Hence, we deduce that charge percolation also acts outside the electric field. In a single point of contact, ionic and electric charges are exchanged at the carbon surface of the MEA. The use of thinner membranes leads to a reduced potential drop. Together with a more homogeneous electric field across the feed water section, this can compensate for the reduction of contact surface between flow electrode and current collector.
Principle 33, in The United Nations Principles to Combat Impunity: a commentary, Frank Haldemann and Thomas Unger, eds., Oxford University Press (2018)
Authors: Laplante Lisa J.
Published: September 2020

This commentary focuses on Principle 33 (Publicizing Reparation Procedures) of the UN Principles for the Protection and Promotion of Human Rights Through Action to Combat Impunity by examining the genesis, normative background, interpretation and practical application of each this principle. The analysis also includes a discussion of the impact of this principle in contemporary transitional contexts and recognizes challenges in its implementation. The author highlights that governments have an obligation to conduct outreach and information campaigns in order to protect the right to information enjoyed by people who have suffered violations of their human rights and have a right to access a reparations through an administrative reparation program.
The Transformational Leadership Practices of National Board Certified School Librarians in North Carolina
Authors: Hirsh Kimberly
Published: September 2020

This study describes a questionnaire survey of school librarians in North Carolina who have received advanced certification from the National Board of Professional Teaching Standards. The survey was conducted to identify the transformational leadership practices of these school librarians and assess their ability to implement professional leadership guidelines. School librarians’ leadership practices were assessed using the Leadership Practices Inventory, 3rd Edition (LPI). School librarians perceived themselves as possessing a high level of transformational leadership in the five exemplary practices identified by the LPI: Modeling the Way (MTW), Inspiring a Shared Vision (ISV), Challenging the Process (CTP), Enabling Others to Act (EOA) and Encouraging the Heart (ETH). They perceived themselves as being very strong at MTW and EOA. They were less successful at ISV and CTP. Overall, they were very successful in implementing professional leadership guidelines. Successful implementation of these guidelines was highly correlated with ISV and CTP.
Organizing and Describing Information for Children
Authors: Hirsh Kimberly
Published: September 2020

Developmental psychology tells us that children have different cognitive capacities than adults (Bilal, 2007; Druin, 2005; Kuhlthau, 1988). Information retrieval research findings illustrate how this plays out in children’s information behaviors and provide a starting point for designing information organization systems that meet children’s unique needs. Controlled vocabularies and hierarchies can be designed to match children’s vocabulary and cognitive structures, providing a higher information seeking success rate. Metadata schemas designed for children should include classes and attributes of resources that adults might not consider, such as physical appearance, age of main character, and text complexity. Vocabularies, hierarchies, and schemas can be designed not just with children’s needs in mind, but with children as partners in the design process. While there is some research describing the design process and its products, little research addresses the effectiveness of child-driven information organization schemes. Future research might address this gap. This literature review provides an overview of the extant research surrounding organizing and describing information for children's use.
Cognitive Reappraisal and Self-Compassion as Emotion Regulation Strategies for Parents during COVID-19: An Online Randomized Controlled Trial
Authors: Preuss Hanna , Capito Klara , van Eickels Rahel Lea , Zemp Martina , Kolar David R.
Published: September 2020

Objective. Parenting during pandemic restrictions places extreme demands on everyday family life, leading to increased stress levels for parents and distressed parent-child interactions. This RCT aimed to investigate whether cognitive reappraisal and self-compassion are helpful emotion regulation (ER) strategies to reduce individual and parental stress during the COVID-19 pandemic.Method. An online intervention for parents was developed focusing on the application of ER strategies to pandemic requirements of families. A sample of 265 parents were randomly assigned to either cognitive reappraisal (CR; n = 88), self-compassion (SC; n = 90) or wait-list control (WLC; n = 87) group. Interventions included two video sessions (day 1 and day 3) and three email reminders to transfer the application of ER strategies to daily family life (days 2, 4, 5). Parents’ perceived individual stress and parental stress were assessed at baseline (T0), at T1 prior to the booster session on day 3, and at T2 (7 days after baseline).Results. Significant decreases from T0 to T2 emerged for both primary stress outcomes in both intervention groups. Individual stress significantly decreased in CR compared to WLC at T2, but not compared to SC. No time × group interactions for parental stress were found. However, mediation analyses suggested that parental stress was indirectly decreased via reductions in individual stress for CR compared to WLC at both time points.Conclusions. COVID-19 will not be the last pandemic to affect family life. Cognitive reappraisal as a brief online intervention can ease acute stress and strengthen the mental health of parents in acute crises.
Watching disgustedly? Game of Thrones and Disgust Sensitivity
Authors: Puthillam Arathy , Karandikar Sampada
Published: September 2020

The HBO show Game of Thrones is fascinating, because despite many of its plot points involving the elicitation of disgust, an emotion associated with avoidance behaviors, its viewership has only surged. We explore the relationship between disgust sensitivity and perception of scenes involving moral, sexual, and pathogen disgust in the show by providing participants with descriptions of such scenes. Participants included those who had never seen the show, those who had seen the show at least once, and those who had seen the show multiple times. We found that those who had watched the show once rated the scenes as less disgusting (overall and for moral and sexual disgust) than those who had not. We also investigated sex differences in disgust and found that women rated the scenes as more aversive than men, especially those involving moral and sexual disgust. Finally, those with more opposite sex siblings were more repulsed by the scenes, especially those involving sexual disgust. The present study adds to a long list of studies that analyses popular culture from an adaptive lens and adds to the notion that popular culture is a ‘cultural remain’ of the evolved human mind.