bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioperiferia Urbana. Resignificación del hábitat popular en la localidad de Ciudad Bolívar, Bogotá
Authors: Guerrero Torrenegra Alejandro Jesus , De los Ríos Arce Andrés Felipe
Published: February 2023

Este articulo explora la forma de reproducción socioespacial del hábitat a partir de la organización espontánea de los asentamientos informales, ya que la planificación urbana Estatal se convierte en marginalización de las formas de organización de los asentamientos populares. Por esta razón se propone la Bioperiferia urbana como modelo teórico-práctico para comprender las practicas inherentes de la participación colectiva y organización popular del territorio, que conlleva a la consolidación de diferentes formas y paisajes alternativos como consecuencia de las dinámicas físico-espaciales. La metodología tiene un enfoque mixto: cualitativo y cuantitativo. La primera categoría de la investigación evalúa la morfología urbana, la segunda categoría se reconocen las formas de transformación espacial y el imaginario popular de sus habitantes. Estas dos categorías de estudios resignifican los valores y procesos de producción del espacio autoconstruido que determina la lógica de ocupación y organización popular ligada con las acciones directa de los residentes para mejorar su vecindario.
THE IMPACT OF REMITTANCES ON ECONOMIC DEVELOPMENT IN THE CENTRAL AND EASTERN EUROPEAN COUNTRIES
Authors: Kersan-Škabić Ines , Tijanić Lela
Published: February 2023

Emigration flows and their relations with economic development can be observed through different aspects, where one of the important questions is the role of the remittances, and transfer of foreign money to home countries. The objective of this study is to investigate the impact of remittances on economic development in Central and Eastern European countries. A review of previous research on the role of emigration and the impact of remittances on economic development is presented in the first part of the paper. This is followed by panel data analysis. The analysis covers the period after the enlargement of the European Union (EU) in 2004 till the nowadays. The results confirm the positive and statistically significant influence of personal remittances on the economic development of the new EU member states, as well as the positive and statistically significant influence of final consumption, gross fixed capital formation, external trade balance, and foreign direct investments. The positive influence of remittances on economic development should be observed with caution, regarding that remittances are the results of emigration and also are connected with the unfavourable effects of emigration. This study adds to previous research about the significance of remittances in the economies of the new EU member states.
CRYPTO PORTFOLIO OPTIMIZATION THROUGH LENS OF TAIL RISK AND VARIANCE MEASURES
Authors: Tomić Bojan , Žiković Saša , Jovanović Lorena
Published: February 2023

The choice of an adequate risk measure in portfolio optimization depends to a large extent on the characteristics and dynamics of the underlying assets. For investors and asset managers, a range of potential market risks provides much- needed insights into the optimization of their portfolio of assets. Since this paper focuses on multiple risk measures, it presents the investors with a better insight into the potential magnitude of the risk they are faced with. Since the risk-reward optimization target can be adjusted for a broad choice of risk measures in this paper we will test the performance of the classical risk measure i.e. standard deviation versus a tail risk measure such as expected tail loss (ETL). Our goal is to find which of the two offers the better performance for a portfolio of cryptocurrencies and if the differences are statistically significant. The setup for our analysis is testing two optimization targets (MinVar and MinETL) on 10 portfolios of cryptocurrencies randomly chosen from a sample of 70 cryptocurrencies with the highest market capitalization.
DO ICT AND TECHNOLOGICAL DEVELOPMENT FACILITATE SUPPLY CHAIN TRADE?
Authors: Zaninović Petra Adelajda
Published: February 2023

This paper aims to estimate the impact of ICT and technological development of countries on supply chain trade. As proxy measures of supply chain trade, the author applies domestic value added (DVAFX) included in gross-foreign exports, and foreign-value added included in domestic exports (FVA) from the Eora MRIO database while constructing the ICT variable by using confirmatory factor analysis. Furthermore, as a proxy variable for the country’s technological development, the author applies the economic complexity index developed by Harvard’s Growth Lab, conducting her analysis based on the structural gravity model estimated with the Poisson Pseudo-Maximum Likelihood Estimator (PPML). Together with the standard gravity regressors, the model includes the bilateral position of countries in the supply chain. Our panel dataset covers the 2000-2019 period, including 130 world countries. To control for the potential source of endogeneity, the model includes reporter and partner country fixed effects, yearly fixed effects, and country-pair fixed effects. The results confirm a statistically significant relationship between the country’s technological development and supply-chain trade. Technological development enables a country to produce more complex, higher value-added products and thus to be more upstream positioned in the supply chain. The more upstream the country is in the supply chain, the higher the domestic value added is included in its exports.
FACTORS INFLUENCING DIVIDEND PAYOUT POLICY: EVIDENCE FROM LISTED NON-FINANCIAL FIRMS OF THE ZAGREB STOCK EXCHANGE
Authors: Prša Darija , Šestanović Aljoša , Ramljak Ivo
Published: February 2023

This paper aims to assess the impact of financial factors on the dividend payout ratio, and the purpose is to research factors affecting dividend payout in less developed markets and compare them with the results of previous studies. We use the global research platform Screener.co, and the financial statements available on Zagreb Stock Exchange to collect the data. Our sample consists of companies listed on the Zagreb Stock Exchange that paid dividends at least once in the last three years. In the model applied, we covered five years (dividends paid from 2017 to 2021, based on financial fundamentals preceding dividends from 2016 to 2020) using hierarchical linear regression analysis that consists of four explanatory variables: return on equity, return on assets, financial leverage, and free cash flow to revenue. First, the research found high fluctuations in the dividend payout ratio and return on equity variability. Secondly, we found no statistically significant causality between the dividend payout ratio and explanatory variables. The results suggest that other long-term non-financial factors, such as the investors’ expectations, history of paying dividends, and large cash reserves backed by high retained earnings, may have a decisive impact on the dividend payout ratio rather than recent financial factors.
Characteristics of stroke-like lesions on cerebral imaging
Authors: Finsterer Josef
Published: February 2023

Objective – Stroke-like lesions (SLLs) are pathognomonic for mitochondrial ence­pha­lopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome but occur in other mitochondrial and non-mitochondrial disorders as well. This mini-review aims at summarising and discussing recent findings to open up future perspectives how to manage this fleeting phenomenon. Results – Typically, SLLs are dynamic lesions, which increase in size and intensity to regress after a nadir. SLLs are incongruent with a vascular territory, originate frequently from the cortex to spread subcortically, can be monofocal or multifocal, run through an acute (attack) and chronic (remission) stage, and may either completely disappear or end up as laminar cortical necrosis, white matter lesion, subcortical atrophy, cyst, or the toenail sign. On cerebral CT, SLLs are hypodense. SLLs can be best visualized on multimodal MRI showing up as hyperintensity on T2, FLAIR, DWI, and PWI, and as hypointensity on OEF-MRI. On MR-spectroscopy, SLLs typically present with a decreased N-acetyl-aspartate peak and an increased lactate peak. DTI in acute SLLs reveals reduced connectivity, increased global efficiency, and reduced focal efficiency. Tc-HMPAO SPECT of SLLs indicates hyperperfusion and L-iomazenil SPECT reduced tracer uptake. FDG-PET typically shows hypometabolism within a SLL. Conclusion – SLLs present with typical findings on various imaging modalities but the combination of cerebral CT, multimodal MRI, MRS, and PET clearly delineate a SLL from other acute or chronic cerebral lesions.
Role of hyaluronic acid during periodontal therapy & post-periodontal surgeries
Authors: Shukla Kirti , Pebbili Kranti Kiran
Published: February 2023

Hyaluronic acid (HA) is a glycosaminoglycan with a high molecular weight found abundantly in the extracellular matrix of soft periodontal tissues. HA has anti-bacterial & anti-inflammatory action in periodontitis & gingivitis. It is plausible that HA administration to diseased periodontal sites is beneficial during periodontal healing as well as post-surgical healing, thus aiding in the management of the periodontal disease. Data gathered from clinical evidence exhibits that HA’s tissue repairing and wound healing could be beneficial not only in patients affected by gingivitis and periodontitis but also during as well as post-periodontal surgery, with significant improvement in their quality of life. This review discusses the physicochemical, biochemical, and pharmacotherapeutic uses of HA during periodontal therapy as well as post-periodontal surgery.
Stafne bone cyst of mandible: A case report with comprehensive imaging features using cone beam computed tomography and literature review
Authors: Deotale Komal , Lanjekar Ashish , Madne Isha , Tayade Charwak , Akhtar Zareesh , Jaiswal Raksha
Published: February 2023

Stafne’s bone cyst (SBC) is a rare, asymptomatic, unilateral oval shaped radiolucent defect mostly in the posterior region of the mandible below the inferior alveolar canal. This report describes a case of SBC in Central Indian Population, which was an incidental finding in a 65-year old male patient who presented with pain. This article also highlights the literature, differential diagnosis along with use of various diagnostic imaging resources, imaging features and management for this bone defect and adds a new Indian case to literature.
Préstamos a riesgo de mar y redes transatlánticas en el comercio entre Cádiz y la costa del Pacífico sudamericano, 1760-1825
Authors: Lamikiz Xabier
Published: February 2023

Este artículo analiza la financiación de la Carrera de Indias en el periodo colonial tardío y se distingue de la historiografía sobre el crédito mercantil en que adopta una perspectiva transatlántica. Examinamos el principal instrumento de crédito empleado en el Atlántico hispano, el préstamo a riesgo de mar. La ruta estudiada es la que unía a Cádiz con las costas de Perú y Chile. Trazamos la evolución de los préstamos, mostrando su auge antes del comercio libre de 1778 y su ocaso a partir de 1785. Para dilucidar el origen del dinero prestado y la vecindad de los acreedores, se emplean tanto fuentes notariales como correspondencia mercantil. Nuestra investigación muestra que los vecinos de Perú y, en menor medida, Chile financiaron cerca de un cuarto de los capitales prestados en Cádiz. Las redes sociales transoceánicas desempeñaron un papel clave en la asignación y gestión de crédito.
Effects of Six Weeks High-Intensity Interval Training on TGF-β1 and SMAD7 Genes Expression in the Kidney Tissue of Elderly Diabetic Male Wistar Rats
Authors: Faramarziyan Narges , Salesi Mohsen , Rezaei Rasoul , Kooshki Jahromi Maryam
Published: February 2023

Introduction: Diabetic nephropathy is a common complication in the patients with diabetes. The aim of this study was to investigate the effect of six weeks of high-intensity interval training on TGF-b1 and SMAD7 gene expression in kidney tissue of elderly diabetic male Wistar rats.
Methods: In this study, 36 male 21-month old Wistar rats, with the weight of 340 to 390 grams were randomly divided into three groups: healthy control, diabetes, and diabetes- training. The training group, performed high-intensity interval training five times per week for six weeks, healthy and diabetic control groups have not done any exercises. 24 hours after the last training session, rats were sacrificed and kidney tissues were extracted to examine TGF-b1 and SMAD7 genes expression by Real-Time PCR method. To determine the difference among the groups, one-way analysis of variance with Tukeys Post hoc test was used at the significant level of P<0.05. Statistical analysis was done by SPSS software version 16.
Results: The results showed that six weeks of high intensity interval training led to a significant decrease in TGF-b1 gene expression in kidney tissue compared to the diabetic group (P=0.001). In addition, a significant increase in SMAD7 gene expression in kidney tissue was observed in the diabetes- training group compared to the diabetes group (P=0.008).
Conclusion: According to the findings of the present study, it seems that high-intensity interval training can probably exert protective effects against nephropathy by reducing the expression of the TGF-b1gene and increasing the expression of the SMAD7 gene in kidney tissue. Because this research was conducted on elderly diabetic rats, it is suggested to check and confirm this training method in diabetic human models.
Evaluation of the Protective Effect of Human Platelet-Rich Plasma on Spermatogenesis and Sperm Chromatin Condensation Following Ischemia-Reperfusion Injury Due to Spermatic Cord Torsion in Mice
Authors: Ramesh Mahya , Khadivi Farnaz
Published: February 2023

Introduction: Torsion of spermatic cord induces ischemic-reperfusion injury which leads to testicular dysfunction, apoptosis of germ cells, ROS generation and infertility. Platelet-rich plasma (PRP) is a rich source of growth factors and anti-inflammatory cytokines. In this study, the effects of PRP on spermatogenesis and sperm chromatin condensation after ischemia-reperfusion injury were evaluated.
Methods: Forty adult male mice were procured in the study. Control group, torsion/ detorsion group, negative control group: torsion/ detorsion surgery with intra testicular injection of culture medium, treatment group: torsion/ detorsion surgery with intra testicular injection of PRP. After one cycle of spermatogenesis, histomorphometric evaluation was performed by PAS staining and sperm chromatin condensation was assessed by aniline blue staining. Data was analyzed by using SPSS Statistics and ANOVA followed by Tukey test.
Results: The mean number of spermatogenic cells, Sertoli, Leydig, Myoid, Johnson score and mean diameter and thickness of germinal epithelium were significantly decreased following ischemia-reperfusion injury. Mean thickness of seminiferous tubules basement membrane as well as sperm percentage with residual histone increased after ischemia-reperfusion injury (P <0.001). After PRP treatment, there was a significant improvement in the histological structure of the tubules, cell viability, and sperm chromatin condensation (P <0.001). While, a significant difference was observed in comparison with control group.
Conclusion: PRP can partially ameliorate the complications of ischemia-reperfusion injury through its growth factors and anti-inflammatory cytokines involved in angiogenesis and antioxidant activity.
Environmental, Social and Governance Responsibility, financial performance and assets: A study of Exchange Traded Funds
Authors: Rompotis Gerasimos
Published: February 2023

Two research questions are examined in this study with a sample of 168 passive Exchange Traded Funds (ETFs). The first one asks whether a high Environmental, Social and Governance Responsibility (ESG) rating induces investors to allocate more money in an ETF. The empirical findings indicate that the level of assets is not affected by the ESG rating whatsoever, but it is affected by factors such as the historical performance, the expense ratio and the age of each fund. The second question raised concerns the relationship between the performance of an ETF and its ESG rating. The hypothesis examined is that the higher the ESG rating of an ETF is, the higher the return of the ETF should be. The results do not confirm this hypothesis. Not surprisingly, to a large extent, the performance of ETFs is driven by the return of the tracking indexes. To a lesser degree, expense ratio bears a negative impact on ETFs’ performance.
Električni rotacijski stroji
Authors: Zagradišnik Ivan , Slemnik Bojan
Published: February 2023

Uvod: osnovne oblike magnetnega kroga rotacijskih strojev, vrtilno magnetno polje ter harmonske komponente magnetnega polja, navitja izmeničnih strojev, faktorji navitja različnih vrst navitij, inducirane napetosti v navitju, opis tokovne obloge, reaktanca navitij, izgube in izkoristek ter segrevanje in ohlajevanje strojev. Asinhronski stroj: opis gradnje in način delovanja, analitična obravnava, obratovanja na togem omrežju, zagoni motorjev in spreminjanje hitrosti vrtenja ter vrtilnega momenta, zaviranje, asinhronski generator, enofazni asinhronski motorji. Sinhronski stroj: opis gradnje in način delovanja, obratovanje na togem omrežju, analitična obravnava, obratovanje nenasičenega stroja na togem in lastnem omrežju, obravnava nasičenega stroja, nestacionarno obratovanje, vzbujalni sistemi in uporaba trajnih magnetov za vzbujanje, sinhronski motorji s trajnimi magneti, koračni motorji. Komutatorski stroj: opis gradnje in način delovanja, navitja, teorija enosmernih strojev, problemi komutacije, elektronska komutacija, karakteristike različnih električnih vezav statorja in rotorja, spreminjanje hitrosti vrtenja, izmenični (univerzalni) komutatorski stroji.
Perspectiva trans: comunicación y cambio de época
Authors: Cabrera Altieri Daniel H. , Angulo Egea María
Published: February 2023

La sociedad mundial, con sus diferentes particularidades, se encuentra en un proceso de transformación profunda. Una transición acelerada orientada desde el neoliberalismo (Laval & Dardot, 2015) y que abarca todos los aspectos de la vida humana.
Do Rewards Build Importer Compliance and Commitment in Overseas Trade?
Authors:   IAGBT, Lee Sun-Ki , Lee Kyung-Jae
Published: February 2023

Purpose - Conflicts of interest can arise in interdependent relationships. For instance, importing agents may act opportunistically and not comply with the exporter’s regulations. Thus, it is important that the principal seeks ways to encourage its agents to perform optimally on its behalf. It becomes necessary to establish a reliable reward system that positively influences agents’ role performance. This study examines whether monetary and non-monetary rewards increase the role performance of overseas agents in international trade.
Design/Methodology/Approach - Analyzing the responses of 50 exporting representatives in South Korean small and medium-sized enterprises (SMEs), it revealed that while compliance and commitment positively influence agents’ role performance, rewards encourage only commitment, not compliance, of agents.
Findings - The findings suggest that non-monetary rewards are as important as monetary incentives in improving the importers’ role performance. In short, the importers’ role performance is improved when non-monetary rewards are actively in place, and their levels of compliance and commitment play the mediating roles.
Research Implications - These findings were vital because exporters want their import agents to be compliant and committed. The results indicated that exporters value long-term commitment more than short-term compliance. Moreover, the role performance of importing agents improves when they are highly committed to their exporter’s cause.
Feeding Therapy in Preterm Infants
Authors: Manuaba Ida Ayu Wulan Kartika Dewi , Dharma Bagus Diva Indra
Published: February 2023

Low Birth Weight (LBW) or Very Low Birth Weight (VLBW) infants often have feeding difficulty issues that impact feeding abilities, leading to complications such as difficulty gaining weight and prolonged length of stay (LOS) in the hospital. Early feeding therapy interventions have good outcomes for LBW or VLBW preterm in accelerating feeding goals, gaining weight, and reducing LOS. This article reported two cases of VLBW patients who were referred from the Pediatric Department to the Physical Medicine and Rehabilitation Department because of feeding difficulties that led to prolonged LOS, in order to achieve better outcomes in spontaneous oral feeding. The feeding therapy intervention was given to the infants every day by the speech therapist. Feeding therapy intervention shows promising results in provoking the proper sucking reflex in VLBW preterm infants, which helps them to achieve better oral feeding ability that accelerates weight gain and reduces LOS in the hospital.
Orthosis Treatment for Patients with Congenital Hip Dislocation
Authors: Rakotonandrianina Manohisoa Nomena Harisambatra , MG., Ando Tatiana Ranaivondrambola, , Tata Tsiahoana Jean Floris , Solofomalala Gaëtan Duval
Published: February 2023

Background: Congenital dislocation of the hip is currently a public health and socioeconomic problem. Delayed treatment impairs the functional prognosis of the affected hip and increases the need for surgical treatment.
Aim: To evaluate the therapeutic results of the treatment by orthosis and the cost of the treatment.
Material and Methods: This retroprospective descriptive study was carried out at the CHUAM of Antananarivo and the CRMM of Antsirabe on patients with congenital hip dislocation treated with braces; from January 2017 to August 2021.
Results: Forty-eight cases were retained during this study. A female predominance was mentioned with a sex ratio of 0.45 and an average age of 7.8 ± 5.5 months at the beginning of the treatment. A left dislocation was observed in 27.1% of cases. Twenty-nine patients were treated with abduction pants. A recentered femoral head showing a good result was present in 37 patients. Five dislocations were observed at follow-up, and 5 residual subluxations. No cases of avascular necrosis of the femoral head have been reported. The total cost of orthosis treatment was on the average of 138.554,5 ± 51.678,8 Ariary.
Conclusion: The age at the start of treatment and the duration of treatment influence the therapeutic outcome. The cost of orthosis treatment was affordable. If the treatment started earlier, the functional prognosis would be better.
Periodontal Debridmanda Farklı Yaklaşımlar
Authors: DOĞAN Didar Betül , ÖZKAL EMİNOĞLU Didem , MADEN Oğuzhan
Published: February 2023

Ağız diş sağlığı genel vücut sağlığını ve yaşam kalitesini önemli ölçüde etkilemektedir. Oral bölgenin ağız ve diş sağlığının devamlılığının sağlanması için kendine özgü florası vardır. Sistemik ve lokal risk faktörlerinin etkisiyle; sağlıklı oral flora ve immün sistem dengesinin bozulmasıyla ağız içi patojen durumlarla karşılaşılabilir. Oral bölgede görülebilen bu patolojiler arasında da periodontal hastalıklar yüksek prevelansa sahiptir. Ağız ve diş sağlığı genel vücut sağlığını etkileyebildiği gibi genel vücut sağlığı da ağız ve diş sağlığını etkiler. Çok faktörlü olması ve çift yönlü etkilenebilmesi nedeniyle de periodontal hastalıkların tedavisi kritik öneme sahiptir. Diştaşı temizliği ve kök düzleştirme (SRP) adı verilen periodontal tedavi altın standart olarak kabul edilmektedir. Bu derlemenin amacı da periodontal tedavinin altın standardı olarak kabul edilen tedavi protokolündeki güncel yaklaşım olarak görülen tüm ağız diştaşı temizliği ve tüm ağız dezenfeksiyonu değerlendirmektir.
Medical negligence in cases decided by the National Consumer Disputes Redressal Commission: A five-year retrospective review.
Authors: Sukumar Sanjay
Published: February 2023

Background: There has been a gradual increase in disputes between doctors and patients in the healthcare system over the years. The aim of this review was to determine the speciality-wise prevalence of medical negligence in cases decided by the National Consumer Disputes Redressal Commission (NCDRC) and the factors responsible for it. Methods: A total of 253 cases of medical negligence decided by the NCDRC from 2015 to 2019 were reviewed and categorised with respect to the number of cases compensated, the speciality involved, the compensation payout for the specialities involved, and the nature of the error leading to negligence. Results: Among the cases analysed, negligence was identified in 135(53%) cases. Of these, the incidence of negligence was highest in surgery [37(27%)], followed by obstetrics and gynaecology (OBG) [29(21%)]. The highest compensation payouts were Rs 1.38 crore and Rs 1.1 crore in the paediatrics and OBG specialties, respectively. The common errors were lack of skill/care in the treatment of the patient [62(36%)] and failure to maintain accurate medical records [38 (22%)]. Conclusion: The study of adverse events in healthcare practice can improve the quality of patient care, and steps can be taken to reduce such events. Many adverse events are preventable by improving the skill/care in treatment and meticulous record keeping.
Understanding the Logic and Complexity of Persuasive Design, Technology, 6G and Facebook Communication
Authors:   Department of Visual Communication, Nehru Arts and Science College, Nehru Garden, T.M.Palayam, Coimbatore, Tamil Nadu- 641105, India, MR Dr K Pradeep , MR Dr. A Kovalan ,   Associate Professor, Department of Computer science, Nehru Arts and Science College, Coimbatore, Tamilnadu, India., MR Dr.PrasanthKoothoor ,   Asst. Prof. Dept. of Media Studies, Karunya University, Coimbatore, MR Mr. Baiju Paul ,   Asst. Prof. Nehru Arts and Science College, Coimbatore
Published: February 2023

In the contemporary world, technology is an extremely powerful and magnificent apparatus in human life and its history which can be used for human development and social wellbeing. The Persuasive Technology is generally defined as technology meditated to change user behavior, and attitude through persuasive sense and social influence. Social science studies and Laboratory show that such persuasive entreaties are very effective at persuading behavior when tailored to the individual. The persuasive technology its design have created a very magical attachment in the social media platform. The innovative employability in the persuasive sense, inventions of 6G made very challenging task for the scientist and the technology expert because their existence are vastly influence by internet and algorithm and artificial intelligence. This chapter explore the technology-centric persuasive design and the Facebook communications dimension, challenges and exertion in using 6G communication.
Porous ZnO-ZnAl2O4-CuO Nanocomposites Synthesized by Polymer-Salt Method for Photocatalytic Water Purification and Splitting
Authors: Shelemanov Andrey , Tincu Artiom , Evstropiev Sergey , Nikonorov Nikolay , Vasilyev Vladimir
Published: February 2023

In this work, the adsorption and photocatalytic properties of ZnO-ZnAl2O4 nanosized composites synthesized by the polymer-salt method have been studied. To evaluate the efficiency of adsorption, experiments were carried out on the decolorization of aqueous solutions of the Chicago Sky Blue diazo dye. The adsorption process is divided into two stages, at the first stage the dye is rapidly adsorbed on the outer surface of the composite particles, at the second stage the dye diffuses into the pores of the material. It was noted that the rate of photocatalytic decomposition of the dye is higher than the rate of the adsorption process, which indicates the occurrence of photocatalytic decomposition of dye molecules both on the surface of the composites and in the liquid phase. With an increase in the light intensity, the photocatalytic process is significantly accelerated, linearly at low intensities, and at high intensities the dependence becomes a power law.
Optimal UAV Hangar Locations for Emergency Services Considering Restricted Areas
Authors: Braßel Hannes , Zeh Thomas , Fricke Hartmut , Eltner Anette
Published: February 2023

With Unmanned Aerial Vehicles (UAV), a swift response to urgent needs like search \& rescue missions or medical deliveries can be realized. Simultaneously, the legislator is establishing so-called geographical zones, which restrict UAV operations to mitigate the air and ground risk to third parties. These geographical zones serve a particular safety interest, but they may also hinder the efficient usage of UAVs on time-critical missions with a range-limiting battery capacity. In this study, we address a facility location problem for up to two UAV hangars with a robust optimization model considering demand hotspots, geographical zones as restricted areas, a standard mission to satisfy battery capacity constraints, and the impact of wind scenarios. To this end, water rescue missions are used exemplary, for which positive and negative location factors for UAV hangars and areas of increased drowning risk as demand points are derived from open-source georeferenced data. Optimal UAV mission trajectories are computed with an A* algorithm considering five different restriction scenarios. As this pathfinding is very time-consuming, binary occupancy grids and image processing algorithms accelerate the computation by identifying either entirely inaccessible or restriction-free connections beforehand. For the optimal UAV hangar locations, we maximize accessibility while minimizing the service time to the hotspots, resulting in a decrease from the average service time of 570.4 s for all facility candidates to 351.1 s for one and 287.2 s for two optimal UAV hangar locations.
Characterising Hospital Admission Patterns and Length of Stay in the Emergency Department at Mater Dei Hospital Malta
Authors: Garg Lalit , Attard Natasha , Caruana Roberta J , Pawar Bhushan Dinkar , McClean Sally I , Buttigieg Sandra C , Calleja Neville
Published: February 2023

Healthcare professionals and resource planners can use healthcare delivery process mining to ensure the optimal utilisation of scarce healthcare resources when developing policies. Within hospitals, patients' Length of Stay (LOS) and volume of admitted patients, in terms of number and characteristics (age, gender, and social deter-minants), are significant factors determining daily resource requirements. In this study, we used Coxian phase-type Distribution (C-PHD) based Phase-Type Survival (PTS) trees for analysing how covariates such as admission date, gender, age, district, and admissions source influence the admission rate and LOS distribution. PTS trees. This study used a two-year data set (2011-2012) of patients admitted to the Emergency Department at Mater Dei Hospital to generate models and an independent one-year data set (2013) of patients admitted to the Emergency Department at Mater Dei Hospital to evaluate. The PTS tree effectively clusters patients based on their LOS, considering the prognostic significance of different covariates related to patients' characteristics. Charac-terising these covariates provided meaningful results about LOS. Similarly, the PTS tree was used to effectively cluster patients based on the admission rate, considering the prognostic significance of these covariates.
G4v and the Correspondence Principle
Authors: Piasecki Daniel
Published: February 2023

G4v is a four-vector theory of gravitation proposed by Mead (2015) which reproduces several major results commonly celebrated for the tensor-based approach of General Relativity (GR). Here, we show that G4v obeys the correspondence principle, an important test of any relativistic theory. We derive the non-relativistic Lagrangian and Energy expressions at the limit of low speeds and potentials, complete with the correct terms for potential energy (something traditional Special Relativity is incapable of achieving). Although most predictions of G4v line up with GR, the polarization of the gravitational waves was shown to be starkly different. We await tests of G4v in future gravitational wave polarization experiments.
Forgotten Traces of the Buddhist Incantation Practice from Early Korea: Incantation of Wish-Fulfillment (Mahāpratisarā) Amulet Sheets from the Silla Kingdom
Authors: Han Joung Ho , Kim Youn-mi
Published: February 2023

Through an investigation of recently discovered Incantation of Wish-Fulfillment amulets from the Silla kingdom, this paper reveals that early Korea had more diverse forms of dhāraṇī practices than previously assumed. This paper’s analysis of these amulets from Korea contributes toward filling the gap in our current understanding of the material practice pertaining to the Incantation of Wish-Fulfillment widely practiced in medieval East Asia. Based on an interdisciplinary analysis of the two amulet sheets of the Incantation of Wish-Fulfillment from Silla, this paper explored hitherto unknown aspects of early Korean dhāraṇī practice. Previously, the only material dhāraṇī practice in early Korea was thought to be the enshrinement of textual relics in pagodas based on the Pure Light Incantation, which has little connection to contemporaneous Chinese dhāraṇī practice. However, the newly discovered Incantation of Wish-Fulfillment amulets, whose date this paper inferred to be between the eighth and ninth century, show that the Unified Silla also had a dhāraṇī practice closely linked to the Chinese practice. However, unlike the Chinese Incantation of Wish-Fulfillment amulets that were buried in tombs, the Silla amulets were likely enshrined in one of the pagodas erected on Mount Nam, Gyeongju. At the same time, the Silla epigraph from Myogilsang Pagoda at Haeinsa shows that the Incantation of Wish-Fulfillment was placed in the pagoda so as to wish for good afterlives of the soldiers who died at the battle, suggesting that placing the Incantation of Wish-Fulfillment in a pagoda had a function similar to that of burying the Chinese amulet in the tomb.
Метод решения сеточных уравнений для задач гидродинамики в плоских областях
Authors: Сухинов Александр Иванович , Sukhinov Alexander Ivanovich , Чистяков Александр Евгеньевич , Chistyakov Alexander Evgenjevich , Никитина Алла Валерьевна , Nikitina Alla Valerevna , Атаян Ася Михайловна , Atayan Asya Mikhaylovna , Литвинов Владимир Николаевич , Litvinov Vladimir Nikolaevich
Published: February 2023

Статья посвящена численной реализации математической модели гидродинамического процесса в расчетной области с «вытянутой геометрией», когда ее характерные размеры в горизонтальном направлении значительно превышают вертикальный размер. Это типичное свойство мелководного водоема или прибрежной системы вызывает необходимость в разработке специализированных методов решения, возникающих в процессе дискретизации сеточных уравнений. При решении задачи переноса в мелководном водоеме показала свою эффективность явно-неявная разностная схема. Переход между временными слоями можно рассматривать как итерационный процесс для решения задачи диффузии-конвекции на установление. Данная идея легла в основу формирования предобуславливателя в предложенном методе решения сеточных уравнений, полученных при аппроксимации задач гидродинамики в областях с «вытянутой геометрией». Проведен численный эксперимент с разработанным программным модулем, который позволил оценить норму вектора невязки, полученной при решении сеточных уравнений задачи расчета давления на основе модифицированного попеременно-треугольного метода (МПТМ) и метода решения сеточных уравнений с предобуславливателем трехдиагонального вида с учетом гидростатического приближения. Согласно специфике разработанного метода, он является эффективным при решении задач водной экологии в случае расчетной области, когда еe горизонтальные размеры значительно превышают вертикальные размеры.
Analisis Karakteristik Psikologi Kepribadian Atlet Bola Voli Kabupaten Cianjur Menuju PORDA Memasuki Tahun 2021
Authors: Permana Agung , Syamsul Taufik Muhamad , Hidayat Suharto Taufik , Rahmat Ayi , Usmaedi  , Arini Ira , Arini Ira
Published: February 2023

Proses menemukan identitas remaja sering muncul konflik fisik dan perilaku, perbedaan kepribadian ini disebabkan oleh tidak adanya keharmonisan dalam suasana hati masing-masing individu, konflik remaja sering dijumpai dalam pertandingan olahraga, seperti olahraga bola voli remaja, keberadaan kepribadian yang berbeda didasarkan pada adanya faktor-faktor yang membentuk kepribadian atlet yang luas. Tujuan penelitian ini adalah untuk mendeskripsikan faktor-faktor yang membentuk kepribadian atlet bola voli. Pendekatan penelitian bersifat deskriptif kualitatif. Pemilihan subjek menggunakan teknik pemeriksaan sejawat  yang berarti ujian dilakukan dengan mengumpulkan teman sebaya yang merupakan teman sebaya, yang memiliki pengetahuan umum yang sama dengan apa yang sedang dipelajari, sehingga dengan mereka peneliti dapat,  meninjau  persepsi, pandangan dan analisis yang sedang dilakukan. Pemilihan subjek yang dimaksud adalah subjek memasuki masa remaja (15 hingga 19 tahun), secara aktif mengikuti pertandingan resmi. Metode pengumpulan data adalah wawancara, observasi, dan studi dokumentasi. Teknik analisis data menggunakan reduksi data, kategorisasi, sitensiasi, dan menyusun hipotesis kerja.
Construction and Application of “Active Prediction-Passive Warning” Joint Impact Ground Pressure Resilience Prevention System: Take the Kuan Gou Coal Mine as an Example
Authors: Cao Jiantao , Zhang Shuai , Xu Huicong , Li Wei , Wang Jindong
Published: February 2023

With the increasing depth and intensity of coal mining, the impact on ground pressure has become one of the main disasters facing mining, seriously threatening mine safety. Introducing the concept of toughness urban design, building a joint toughness prevention and control system based on active prediction and analysis of the impact pressure risk at the back mining face according to the geological deposit conditions and mining technology conditions and passive warning using monitoring data to explore the impact precursor characteristics is an important basis for impact pressure management and has important engineering significance to ensure the safe back mining. In this paper, firstly, the whole working face is divided into small unit areas, and the BP neural network prediction model is constructed to predict and analyze each small unit separately, and the distribution of impact ground pressure hazard level in different areas of the working face is derived. Next, a FLAC numerical model was established to analyze the stress distribution and migration characteristics at different retrieval distances of the working face and to explore the main distribution areas of impact hazard. Finally, the trend method, critical value method, and dynamic rate of change method were applied to determine the early warning indicators of impact ground pressure in the Kuan Gou coal mine, establish a comprehensive early warning method of impact ground pressure applicable to the Kuan Gou coal mine, and carry out field application with good effect. The findings of this paper have good scientific significance and reference value for promoting impact hazard analysis and early warning in mines with similar geological conditions and mining technology conditions in China.
The Brachycephalic Paradox: The Relationship Between Attitudes, Personality, Knowledge of Health Problems, and Dog-Human Eye Contact
Authors: Bognár Zsófia , Kubinyi Enikő
Published: February 2023

Brachycephalic, or “flat-faced” dogs are popular despite the health problems they often face. We assumed that individuals who like these dogs have lower knowledge about the associated health problems and a specific personality profile and highly value the tendency of these dogs to form eye contact with humans. We conducted an online survey with 1,156 respondents, and some of the results were contrary to our expectations. People with a positive attitude toward brachycephalism associated more health problems with it and did not prefer photos of dogs making eye contact (looking into the camera) over those looking away. They were also found to be younger, more often women, had children, had lower levels of education, and a higher level of agreeableness, conscientiousness, and dog-directed emotional empathy. The results suggest that the tendency of brachycephalic dogs to form eye contact does not play a role in their popularity and that high emotional empathy and knowledge about health problems do not discourage people from liking these dogs. Future research is necessary to examine how behaviours other than eye-contact contribute to the popularity of flat-faced dogs, as well as how owners’ sensitivity to fashion trends and their lack of recognition of the dogs’ health issues contribute.
Association of SGLT-2 inhibitors with bacterial urinary tract infection in type 2 diabetes
Authors: Tanriverdi Mustafa , Bastemir Mehmet , Demirbakan Hadiye , Ünalan Alperen , Türkmen Merve , Tanrıverdi Gülşen Özkan
Published: February 2023

Objective
We aimed to investigate the factors associated with UTI in patients with T2D whether being treated with SGLT-2i or not.
Methods
Adult patients with T2D, whose urine culture results were available, were analyzed retrospectively. Urine culture was obtained from mid-flow urine. Antibacterial treatment was given to the patients with UTI, which was defined by positive urine cultures and/or clinical findings.
Results
A total of 101 patients were included. Median age was 56 (45–67), 56.4% (n = 57) of the patients were female. Urine culture was positive in 54.9% (n = 28) and 16% (n = 8) of Group A (n = 51) and Group B (n = 50), respectively. Of those for whom urine culture was positive, E. coli was isolated in 83.3% (n = 30), and both E. coli and Klebsiella pneumonia (K.pneumonia) were isolated in 16.7% (n = 6). K. pneumonia was isolated only from Group A. The need for and duration of hospitalization were higher in Group A (p < 0.001). UTI was detected in 60 patients. ROC analysis showed that a HbA1c of > 5.8% was associated with UTI with good accuracy (AUC: 0.835, p < 0.001). In multiple logistic regression analysis, SGLT-2i use and glucosuria were positive predictors for UTI (p = 0.004, Odds Ratio: 1984.013; and p = 0.028, and Odds Ratio: 12.480, respectively).
Conclusion
Besides the association of HbA1c and BMI with UTI, SGLT-2i use and glucosuria predicted UTI. Urine culture is important with respect to the choice of antibacterial treatment, especially in those patients under SGLT-2i treatment. The effect of SGLT-2i on the development of UTI is independent of baseline BMI score or HbA1c.
Uterine Leiomyosarcoma with a Novel RAB2A-PLAG1 Gene Fusion
Authors: Sham Sunder , Hosseini Hossein , Kokabee Mostafa , Bendari Ahmed , Reham Al-Refai , Zhong Xuelin , Vele Oana , Villella Jeannine A. , Unger Pamela , O'Leary Xiaoqing
Published: February 2023

Uterine leiomyosarcoma (ULMS) constitutes 1% of all uterine malignancies and is the most common subtype of uterine sarcoma. In some cases, distinguishing ULMS from endometrial stromal sarcoma (ESS) can be challenging as they may display histological and immunohistochemical overlap. In such cases, molecular studies such as RNA sequencing to detect gene rearrangements can help arrive at the definitive diagnosis. We report a unique case on ULMS with a novel RAB2A-PLAG1 gene fusion, which to our knowledge, is the first case reported in the English literature. Case Presentation: An 80-year-old woman presented to our hospital with a one-month history of pelvic pain and abnormal uterine bleeding. Imaging was notable for a large necrotic uterine mass, a thickened endometrium, and uterine fibroids. A subsequent endometrial biopsy (EMB) revealed an unremarkable transformation zone epithelium. After 4 months, the patient presented with persistent symptoms. One solid mass within the endometrium was found on imaging. Endometrial curettage (EMC) revealed a malignant uterine mesenchymal neoplasm with histologic findings suggestive of ULMS and ESS. The patient underwent a total hysterectomy with bilateral salpingo-oophorectomy. Immunohistochemical study performed on the resection specimen was inconclusive. RNA sequencing identified a novel RAB2A-PLAG1 gene fusion, and a diagnosis of ULMS was rendered. Conclusion: This is the first case of a ULMS with RAB2A-PLAG1 gene fusion. Pathologists should be cognizant of the extensive morphologic and immunophenotypic overlap between various uterine mesenchymal neoplasms. In challenging cases, molecular studies are crucial in allowing the pathologist to arrive at the final diagnosis.
SYVN1-mediated ubiquitylation directs the localization of MCT4 in plasma membrane to promote the progression of lung adenocarcinoma
Authors: Zhao Meng , Yang Lexin , Huang Chen , Chang Jiao , Jin Yu , Zhao Gang , Yue Dongsheng , Qie Shuo , Li Ren
Published: February 2023

Tumor cells mainly generate energy from glycolysis that is commonly coupled with lactate production even under normoxic conditions. As one critical lactate transporter, monocarboxylate transporter 4 (MCT4) is highly expressed in glycolytic tissues like muscles and tumors. Overexpression of MCT4 is associated with poor prognosis for patients with various tumors. However, it remains largely unknown how MCT4 function is post-translationally regulated. Taking advantage of human lung adenocarcinoma (LUAD) cells, this study reveals MCT4 can be polyubiquitylated in a non-proteolytic manner by SYVN1 E3 ubiquitin ligase. The polyubiquitylation facilitates the localization of MCT4 into the plasma membrane that enhances the activity of MCT4 to export lactate; in accordance, SYVN1 knockdown effectively reprograms metabolism that is characterized by reduced glycolysis and lactate production, which can be reversed by ectopic MCT4 expression. Biologically, SYVN1 knockdown successfully compromises cell proliferation and tumor xenograft growth in mouse models. Clinicopathologically, overexpression of SYVN1 is associated with poor prognosis in patients with LUAD, highlighting the importance of SYVN1-MCT4 axis contributes to the progression of LUAD through metabolic reprograming.
Bibliometric analysis of the global scientific production on machine learning applied to different cancer types
Authors: Ruiz-Fresneda Miguel Angel , Gijón Alfonso , Morales-Álvarez Pablo
Published: February 2023

Cancer disease is one of the main causes of death in the world, with million annual cases in the last decades. The need to find a cure has stimulated the search for efficient treatments and diagnostic procedures. One of the most promising tools that has emerged against cancer in recent years is Machine Learning (ML), which has raised a huge number of scientific papers published in a relatively short period of time. The present study analyzes global scientific production on ML applied to the most relevant cancer types through various bibliometric indicators. We find that over 30000 studies have been published so far and observe that cancers with the highest number of published studies using ML (breast, lung, and colon cancer) are those with the highest incidence, being USA and China the main scientific producers on the subject. Interestingly, the role of China and Japan in stomach cancer is correlated with the number of cases of this cancer type in Asia (78% of the worldwide cases). Knowing the countries and institutions that most study each area can be of great help for improving international collaborations between research groups and countries. Our analysis shows that medical and computer science journals lead the number of publications on the subject and could be useful for researchers in the field. Finally, keyword co-occurrence analysis suggest that ML-cancer research trends are focused not only on the use of ML as an effective diagnostic method, but also for the improvement of radiotherapy- and chemotherapy-based treatments.