bluuebunny/crossref_metadata_2025 huggingface dataset:
ТЕОРЕТИЧЕСКИЕ И МЕТОДИЧЕСКИЕ АСПЕКТЫ ИССЛЕДОВАНИЯ ПРОЦЕССА СОЦИАЛЬНОГО РАЗВИТИЯ РЕГИОНА
Authors: Уляева А.Г. , Орешников В.В.
Published: August 2024

Проводится компаративный анализ существующих подходов к понятию социального развития. Представлены подходы к исследованию данного процесса в рамках классической и современной социологической науки. Дана характеристика определениям социального развития с позиции современной региональной экономики, проведена их классификация с позиции эволюционного, структурного, ситуационно-процессного и управленческого подходов. Представлена взаимосвязь социального развития с близкими к нему терминами: «социально-экономическое развитие», «благосостояние населения», «качество жизни» и «уровень жизни», «человеческий капитал», «человеческий потенциал», «социальная сфера». Предлагается авторское определение социального развития региона, основанное на представлении его структурно-процессных компонентов. Представлены результаты анализа существующих подходов к комплексной оценке уровня социального развития региона, выявлена дифференциация методик оценки как по структуре системы индикаторов, так и по количественному составу показателей оценки.
СОСТОЯНИЕ И НАПРАВЛЕНИЯ РАЗВИТИЯ СПОРТИВНОГО ТУРИЗМА В ОБРАЗОВАТЕЛЬНЫХ ОРГАНИЗАЦИЯХ КЧР
Authors: Айбазов А.Х.
Published: August 2024

В данной статье автором выделены наиболее востребованные в Карачаево-Черкесской Республике виды туризма среди сотрудников, педагогов, обучающихся учреждений высшего образования и туристско- спортивного актива Республики. Рассмотрены более углубленно теоретические принципы и разработаны практические рекомендаций по совершенствованию спортивного туризма в Карачаево-Черкесской Республике. В результате внедрения инновационных технологий и технологического обновления образовательных отраслей снизятся затраты на предоставляемые услуги, а следовательно, повысится их доступность. Увеличение заработной платы работникам образовательной сферы будет способствовать привлечению молодых квалифицированных кадров. Предложены конкретные практические рекомендаций по совершенствованию и развитию туризма в ряде организаций Карачаево-Черкесской Республике.
ПОСЛЕДСТВИЯ САНКЦИОННОЙ ПОЛИТИКИ ЗАПАДА ДЛЯ ПЕРСПЕКТИВ МИРОВОГО ЭКОНОМИЧЕСКОГО РОСТА
Authors: Варвус С.А.
Published: August 2024

процессов в международные связи экономического, социального, политического, культурного характера вовлечено большое количество государств. Именно поэтому проводимая в отношении нашей страны санкционная политика затрагивает мировую экономику в целом. Статья посвящена анализу последствий антироссийских санкций для мирового экономического роста. Автор доказывает, что нацеленное на дестабилизацию и разрушение российской экономики беспрецедентное санкционное давление со стороны западных стран и США влечет за собой негативные последствия для всего мира. Статья может представлять интерес для широкого круга исследователей мировой экономики, акцентирующих свое внимание на проблемах и последствиях санкционной политики.
АКТУАЛЬНЫЕ ВОПРОСЫ НАЛОГООБЛОЖЕНИЯ В РОССИИ В 2023 Г.
Authors: Кацуба Е.Е.
Published: August 2024

В статье проведен анализ наиболее значимых изменений налогового законодательства в России 2023 г. в части новой модели уплаты налогов (единый налоговый платеж), страховых взносов и налога на доходы физических лиц.
ЦИФРОВЫЕ ЭКОСИСТЕМЫ КАК СПОСОБ ВЕДЕНИЯ УПРАВЛЕНЧЕСКОГО УЧЕТА ПРЕДПРИЯТИЯМИ СРЕДНЕГО И МАЛОГО БИЗНЕСА
Authors: Печенкина А.В. , Осипов В.С.
Published: August 2024

В исследовании был проведен ретроспективный анализ развития понятия «цифровая экосистема» в зарубежной и отечественной научной литературе   Рассмотрено влияние цифровых экосистем на экономическое развитие субъектов малого и среднего бизнеса. Выявлены и проанализированы достоинства и недостатки процесса внедрения цифровой экосистемы для ведения управленческого учета. Предложены критерии для анализа цифровых экосистем, предназначенных для ведения управленческого учета. По предложенным критериям был проведен анализ существующих в мировой и отечественной практике цифровых экосистем, позволяющих вести управленческий учет. Авторами была предложена концепция цифровой трансформации для субъекта малого и среднего бизнеса в области управленческого учета с использованием экосистем, предусматривающие три компонента – оценки готовности к внедрению, внедрение, анализ результатов и проведение корректирующих мероприятий.
ЭФФЕКТИВНОСТЬ ПЛАНИРОВАНИЯ КОНТРОЛЬНЫХ МЕРОПРИЯТИЙ КАК ФАКТОР МИНИМИЗАЦИИ РИСКОВ В СИСТЕМЕ ВНУТРЕННЕГО ГОСУДАРСТВЕННОГО (МУНИЦИПАЛЬНОГО) ФИНАНСОВОГО КОНТРОЛЯ
Authors: Летуновский В.В.
Published: August 2024

В статье представлены результаты исследования направлений совершенствования планирования внутреннего государственного (муниципального) финансового контроля с учетом положений федерального стандарта «Планирование проверок, ревизий и обследований», способствующих повышению эффективности планирования контрольных мероприятий. Дана оценка взаимосвязи возникающих в контрольной деятельности Казначейства России рисков с эффективным  планированием контрольных мероприятия. Раскрыта значимость оценки рисков на этапах  распределения и использования бюджетных средств, определены способы минимизации  рисков при повышении качества планирования контрольно-финансовых мероприятий. Определены  информационные ресурсы, способы и приемы анализа  рисков, используемые для оценки этапов планирования контрольной деятельности и анализа возможных рисковых ситуаций, требующих своевременных мероприятий по предотвращению ожидаемого риска.
ФИНАНСОВАЯ ГРАМОТНОСТЬ НАСЕЛЕНИЯ РЕСПУБЛИКИ МОРДОВИЯ: ОЦЕНКА И НАПРАВЛЕНИЯ ПОВЫШЕНИЯ
Authors: Морозова Г.В. , Еремина О.И. , Семенов М.А.
Published: August 2024

В статье  обосновывается необходимость повышения финансовой грамотности населения, а также  рассматривается влияние уровня финансовой грамотности на  различные хозяйствующие субъекты (государство, финансовый сектор, домашние хозяйства). Представлены результаты мониторинга уровня финансовой грамотности населения Республики Мордовия, который основывался на оценке   финансовых знаний, финансовых навыков и финансового поведения. Предложены  мероприятия, реализация которых позволит сформировать финансовую культуру и рациональное финансовое поведение у населения в регионе.
Зарубежный опыт применения программно-целевого управления расходами бюджетов
Authors: Каирова Ф.А. , Буриков Д.В.
Published: August 2024

Актуальными задачами органов как государственной, так и муниципальной власти на современном этапе является финансирование расходов бюджетов бюджетной системы РФ. В статье рассмотрен опыт применения программно-целевого бюджетирования в ряде зарубежных стран (Великобритания, Канада, Германия, США). Использование данного метода подразумевает четкое формирование целей и определение мероприятий, направленных на достижение данных целей. Для России применение международного опыта с точки зрения стоящих перед государством задач, дает возможность для создания оптимальной национальной модели описания и применения  государственных программ.
ТЕОРИЯ И ОПЫТ ГОСУДАРСТВЕННОЙ ПОЛИТИКИ ПОДДЕРЖКИ ЭКОНОМИЧЕСКОЙ БЕЗОПАСНОСТИ ХОЗЯЙСТВУЮЩЕГО СУБЪЕКТА В УСЛОВИЯХ САНКЦИЙ
Authors: Мартынович С.Н. , Дрожжин А.А.
Published: August 2024

В виду различных событий, случившихся в мире в последние годы, Россия оказалась под сильным давлением санкций со стороны большинства развитых стран мира, которые затронули практически все отрасли экономики: авиакосмическую, нефтегазовую и другие. Это побудило государство к разработке и принятию новых путей стратегического развития российской экономики в целях избежания её упадка. Для этого государство не только старается наладить экономические отношения с другими странами, но также вводит различные меры поддержки экономики внутри страны, в том числе меры, разработанные для поддержания бизнеса и предпринимательства в России. В этой статье рассмотрим основные разработанные государством меры, процент осведомлённости о них, а также возможность использования этих мер, их достаточность для ведения бизнеса российскими предпринимателями в 2024 году и условия получения.
ОЦЕНКА РЕЗУЛЬТАТИВНОСТИ РЕАЛИЗАЦИИ СТРАТЕГИИ СОЦИАЛЬНО-ЭКОНОМИЧЕСКОГО РАЗВИТИЯ РЕГИОНА (НА ПРИМЕРЕ РЕСПУБЛИКИ МОРДОВИЯ)
Authors: Ивашкина Н.В. , Иншаков В.А.
Published: August 2024

Современные геополитические реалии и нестабильная ситуация в мировой экономике выдвигают на передний план задачи регионального стратегического планирования, которые являются значимым инструментом государственного управления в региональном развитии.  «Стратегия социально-экономического развития», являясь одним из ключевых понятий в современной экономике и политике, включает в себя цели, задачи и методы, которые используются для обеспечения устойчивого и сбалансированного развития общества и экономики. Кроме того, стратегия должна обладать такими характеристиками как реалистичность и выполнимость, предполагая разработку сценариев и группы целевых индикаторов, а также плана действий по их достижению, что, несомненно, ведет к повышению шансов на ее успех. В статье представлен сравнительный анализ достижения показателей реализации сценариев «Стратегии социально-экономического развития Республики Мордовия до 2025 года» (Стратегия—2025), сгруппированы факторы, оказавшие наибольшее влияние на результативность реализации стратегии, проведено сравнение показателей стратегии. Все это позволило авторам сделать ряд выводов о том, что в сложившей социально-экономической ситуации основные цели Стратегии—2025 не будут выполнены, и что она не отвечает современным вызовам, а также требуется разработка новой стратегии социально-экономического развития региона, с учетом значительных изменений в глобальной политической и экономической ситуации. Результаты исследования могут быть использованы региональными органами исполнительной власти, научными организациями при разработке стратегий социально-экономического развития регионов.
المقومات الطبيعية في جبل شدا ودورها في تحقيق السياحة المستدامة
Authors: الزهراني زهره أحمد
Published: August 2024

تناول هذا البحث المقومات الطبيعية في جبل شدا ودورها في تحقيق السياحة المستدامة، حيث تضم منطقة الدراسة العديد من الموارد الطبيعية التي يمكن الإستفادة منها في بدء خطة تنموية لتنشيط القطاع السياحي في المنطقة، و وضعت الباحثة عدة تساؤلات لتحقيق اهداف البحث حيث تهدف الدراسة الحالية إلى التعرف على المقومات الطبيعية في منطقة الدراسة، إضافةً إلى معرفة معوقات السياحة في جبل شدا وأبرز التحديات، ومن أجل تحقيق أهداف الدراسة استخدمت الباحثة المنهج الوصفي و الإقليمي، كما واستخدمت الباحثة الملاحظة الشخصية و المقابلة والتي تعد أداة استخدمتها الباحثة لتجمع بيانات بحثها، وتضمنت نتائج الدراسة تأكيد جاذبية جبل شدا حيث يتميز بوجود العديد من التكوينات الصخرية والتي تظهر على شكل تجاويف تشبه الدحول يرجع سبب تكوينها إلى عوامل التعرية التي مرت بها المنطقة، إضافة إلى وجود رسومات ونقوش قديمة في بعض من أجزاء الجبل حيث تعتبر مقومات طبيعية تسهم في تنشيط السياحة الثقافية في منطقة الدراسة، كما أظهرت نتائج الدراسة إلى وجود بعض المعوقات التي تسبب تراجع في الحركة السياحية مثل افتقار منطقة الدراسة إلى المرافق الخدمية والصحية، وأوصت الدراسة بضرورة حصر وتوثيق الموارد والمقومات الطبيعية في جبل شدا في إطار قاعدة بيانات معلوماتية وترويجها، بالإضافة إلى دعم وتشجيع الاستثمار السياحي في جبل شدا واستقطاب رؤوس الأموال المحلية والعالمية للنهوض بالقطاع السياحي في منطقة الدراسة.
HUBUNGAN PANJANG BERAT DAN FAKTOR KONDISI IKAN SEPAT RAWA (TRICHOGASTER TRICHOPTERUS) DI SUNGAI PARIT BARU KABUPATEN MEMPAWAH
Authors: Krisnawati Krisnawati , Sirodjul Ahmad Mulyadi , Rahayu Sri
Published: August 2024

Sungai Parit Baru merupakan sungai yang terletak di Desa Terap, Kecamatan Toho, Kabupaten Mempawah, Kalimantan Barat. Sungai ini memiliki panjang 2300 meter dengan garis lurus dan lebar sungai yang tidak menentu. Jarak antara stasiun 1 ke stasiun 2 sekitar 761 meter dengan lebar sungai masing-masing yaitu sekitar 2 m dan 5 meter. Di perairan ini terdapat beragam jenis ikan. Diantaranya ditemukan ikan Sepat Rawa (Tricogaster trichopterus). Penelitian ini perlu dilakukan untuk mengetahui aspek biologi yang meliputi hubungan panjang berat dan faktor kondisi ikan sepat rawa (Trichogaster trichopterus) yang ada di daerah tersebut. Penelitian ini telah dilaksanakan dari bulan Februari 2023 – April 2023 bertempat di Sungai Parit Baru Kabupaten Mempawah. Penelitian ini bertujuan untuk mengetahui Hubungan Panjang Berat dan Faktor Kondisi Ikan Sepat Rawa di Sungai Parit Baru Kabupaten Mempawah. Metode yang digunakan dalam penelitian ini adalah metode Purposive Sampling. Pengambilan sampel dilakukan pada 2 stasiun di Perairan Sungai Parit Baru dan didapatkan sebanyak 75 ekor ikan, populasi didominasi oleh sebaran ukuran kelas panjang 9,25-10 cm sebanyak 33 ekor. Hasil hubungan panjang berat menunjukan bahwa pola pertumbuhan bersifat allometrik negatif dan alometrik positif. Nilai faktor kondisi ikan Sepat Rawa (Trichogaster trichopterus) berkisar 0,56-2 yang menunjukkan bahwa ikan dalam kondisi gemuk.  Kata Kunci:   Frekuensi Panjang, Ikan Sepat Rawa, Rasio Kelamin, Sungai Parit Baru
STATUS STOK UDANG PUTIH (Penaeus merguiensis de Man, 1888) DARI ZONA 3 MIL YANG DIDARATKAN DI DUSUN PARIT PANGERAN DESA TANJUNG SALEH KABUPATEN KUBU RAYA KALIMANTAN BARAT
Authors: Wulandari Ike Yuni , Adijaya Mardan , Hadinata Fitra Wira
Published: August 2024

Kabupaten Kubu Raya yang merupakan salah satu kawasan sentra produsen udang terbesar di Kalimantan Barat dengan konstribusi mencapai 40,08% pada 2010 dan 39,45% pada 2012, salah komoditasnya ialah Penaeus merguiensis. Penaeus merguiensis termasuk kedalam klasifikasi udang paneid yang komoditasnya menjadi sasaran utama. Udang putih menjadi salah satu udang yang mengalami eksploitasi dimana berdampak pada penurunan stok udang putih. Oleh karena itu perlu dilakukan penelitian untuk mengetahui status stok udang putih di perairan tersebut. Penelitian dilakukan selama 3 bulan menggunakan alat tangkap mini bottom trawl dan menggunakan metode systematic random sampling. Analisis data yang digunakan yakni sebaran frekuensi karapas, hubungan rasio berat total dan panjang total terhadap waktu penangkapan, hubungan panjang total dan panjang karapas, laju pertumbuhan, mortalitas dan laju eksploitasi. Hasil analisis menunjukkan bahwa udang yang tertangkap memiliki sebaran frekuensi antara 12-27,9 mm, rasio berat total dan panjang total mengalami peningkatan pada bulan april yakni 0,098 gram, kemudian mengalami penurunan drastis pada bulan mei yakni 0,075 gram, pola pertumbuhan yakni bersifat allometrik negatif karena nilai b<3 yang artinya pertambahan panjang udang putih lebih cepat daripada pertambahan berat.Kata Kunci: Allometrik, Pertumbuhan, Status Stok, Udang Putih.
PENGARUH KONSENTRASI DAN LAMA PERENDAMAN ROOTONE-F TERHADAP PERTUMBUHAN STEK TANAMAN ANGGUR (Vitis labrusca) VARIETAS ISABELLA
Authors: Purwandhari Arneta Noviana , Susilowati Yulia Eko , Laeshita Putri Laeshita
Published: August 2024

Perbanyakan stek tanaman anggur membutuhkan waktu lama untuk tumbuhnya tunas dan akar. Penambahan Rootone-F bertujuan untuk merangsang pertumbuhan akar dan tunas pada stek. Penelitian dilakukan untuk mengetahui pengaruh Rootone-F dengan konsentrasi dan lama perendaman terhadap pertumbuhan stek tanaman anggur (Vitis labrusca). Penelitian dilaksanakan pada tanggal 27 Agustus sampai 4 November 2022 di Desa Kebonrejo, Kecamatan Salaman, Kabupaten Magelang, Jawa Tengah. Penelitian menggunakan percobaan faktorial (4 x 5) yang disusun dalam Rancangan Acak Kelompok Lengkap (RAKL) dengan dua faktor perlakuan dan diulang tiga kali sebagai blok. Faktor pertama konsentrasi Rootone-F yaitu 100, 300, 500, 700, dan 900 ppm. Faktor kedua lama perendaman Rootone-F yaitu 1, 2, 3 dan 4 jam. Data hasil pengamatan dianalisis menggunakan sidik ragam. Hasil penelitian menunjukkan bahwa konsentrasi Rootone-F memberikan pertumbuhan yang sama pada tinggi bibit, jumlah tunas, jumlah daun, jumlah akar, panjang akar terpanjang dan persentase stek hidup. Lama perendaman stek memberikan pertumbuhan yang sama pada seluruh parameter pengamatan. Konsentrasi dan lama perendaman Rootone-F pada stek memberikan pertumbuhan yang sama pada semua parameter pengamatan.
Regioselective Intermolecular Carboamination of Allylamines via Nucleopalladation for Efficient Vicinal Diamine Synthesis
Authors: Saha Shib Nath , Ballav Nityananda , Ghosh Suman , Baidya Mahiuddin
Published: August 2024

An intermolecular carboamination reaction of allyl amines under Pd(II)-catalysis is reported, expediting the synthesis of valuable vicinal diamines embedded in a functionally enriched linear carbon framework with high yields and exclusive Markovnikov selectivity. Central to our approach is the strategic use of a removable picolinamide auxiliary, which directs the regioselectivity during aminopalladation and stabilizes the crucial 5,5-palladacycle intermediate. This stabilization facilitates oxidative addition to carbon electrophiles, enabling the simultaneous incorporation of diverse aryl/styryl groups as well as important amine motifs, such as sulfoximines and anilines, across carbon-carbon double bonds. The protocol features broad substrate compatibility, tolerance to various functional groups, and scalability. The utility of this method is further demonstrated by the site-selective diversification of pharmaceutical agents. Additionally, these products serve as versatile intermediates for synthesizing heterocycles and function as effective ligands in catalytic transfer hydrogenation reactions. Notably, this work represents a rare instance of nucleopalladation-guided intermolecular carboamination of allylamines.
Performance of Quantum Chemistry Methods for Benchmark Set of Spin–State Energetics Derived from Experimental Data of 17 Transition Metal Complexes (SSE17)
Authors: Radon Mariusz , Drabik Gabriela , Hodorowicz Maciej , Szklarzewicz Janusz
Published: August 2024

Reliable prediction of spin-state energetics for transition metal (TM) complexes is recognized as a challenging and compelling problem in quantum chemistry, with implications for modeling catalytic reaction mechanisms and computational discovery of materials. The computed spin–state energetics are highly variable with the choice of method and credible reference data are scarce, making it difficult to conduct conclusive computational studies of open-shell TM systems. Here, we present a novel benchmark set of first-row TM spin–state energetics, which is derived from curated experimental data of 17 representative complexes containing Fe(II), Fe(III), Co(II), Co(III), Mn(II), and Ni(II) with chemically diverse ligands. The reference values of adiabatic or vertical energy differences are derived from spin-crossover enthalpies (9 complexes) or energies of spin-forbidden absorption bands in reflectance spectra (8 complexes). These are carefully back-corrected for relevant vibrational and environmental effects (due to solvation or crystal lattice) in order to provide the reference values directly comparable with computed electronic energy differences. The new benchmark set makes it possible to assess the accuracy of spin–state energetics from approximate density functional theory (DFT) and wave function methods with a level of statistical reliability not attained in earlier studies. The lowest mean absolute error (MAE) of 1.5 kcal/mol and maximum error of −3.5 kcal/mol are found for the coupled-cluster CCSD(T) method, which outperforms all tested multireference methods: CASPT2, MRCI+Q, CASPT2/CC and CASPT2+δMRCI. Contrary to earlier claims in the literature, the use of Kohn–Sham instead of Hartree–Fock orbitals in the reference determinant is not found to consistently improve the accuracy of the CCSD(T) spin–state energetics. The best performing DFT methods are double-hybrids (PWPB95-D3(BJ), B2PLYP-D3(BJ)) with the MAEs below 3 kcal/mol and maximum errors within 6 kcal/mol, whereas DFT methods traditionally recommended for spin states (e.g., B3LYP*-D3(BJ) and TPSSh-D3(BJ)) are found to perform much worse with the MAEs of 5–7 kcal/mol and maximum errors beyond 10 kcal/mol. The results of this work are relevant for the proper choice of methods to characterize TM systems in computational catalysis and (bio)inorganic chemistry, and may also stimulate new developments in quantum-chemical or machine learning approaches.
Temperature-Induced Phase Transition in 2D Alkylammonium Lead Halide Perovskites: A Molecular Dynamics Study
Authors: Namakian Reza , Garzon Maria Alejandra , Tu Qing , Erdemir Ali , Gao Wei
Published: August 2024

Molecular dynamics simulations are utilized to unravel the temperature-driven phase transition in double-layered butylammonium (BA) methylammonium (MA) lead halide perovskite (BA)$_{2}$(MA)Pb$_{2}$I$_{7}$, which holds great promise in a wide range of optoelectronics and sensor applications. The simulations successfully capture the structural transition from low to high symmetry phases with rising temperatures, consistent with experimental observations. The phase transition initiates at two critical interfaces: the first is between the inorganic and organic layers, where the melting of N-H bonds in BA leads to significant reduction in hydrogen bonding between BA and iodides, and the second is at the interface between top and bottom organic layers, where the melting of the tail bonds in BA triggers the phase transition. Following this, BA cations exhibit a patterned and synchronized motion reminiscent of a conical pendulum, displaying a mix of ordered and disordered behaviors, prior to evolving into a completely molten and disordered state. While the melting of BA cations is the primary driver of the phase transition, the rotational dynamics of MA cations also plays a critical role in determining the phase transition temperature, influenced by the BA-MA interaction. Such interaction alters the polarization patterns of MA cations across the phase transition. In particular, an anti-parallel polarization pattern is observed in low temperature phase. Additionally, displacive elements of the phase transition are identified in the simulations, characterized by the shear and distortion of the inorganic octahedra. Notably, at lower temperatures, the octahedral distortion follows a bimodal distribution, reflecting significant variations in distortion among octahedra. This variation is attributed to an anisotropic hydrogen bonding network between iodides and BA cations. Our study reveals new phenomena and mechanisms extending beyond the order-disorder transition mechanism, shedding new light on potential phase engineering through strategic tuning of organic and inorganic components.
Revolutionizing Parkinson’s Treatment: The Evaluation of Sublingual Dosage Form
Authors: Sanjay More Samidha , Padmasree M
Published: August 2024

Parkinsons disease a prevalent and complex neurodegenerative disorder predominantly affecting the elderly continues to elude a definitive etiological understanding. The therapeutic landscape for Parkinsons disease spans a diverse array of medications and formulations including amantadine L-dopa anticholinergics and dopamine agonists such as selegiline and apomorphine. Despite these options managing the associated treatment side effects remains a substantial clinical challenge encompassing fluctuations dyskinesias and psychological manifestations. In the realm of Parkinsons disease management various administration routes including parenteral nasal and oral routes are employed each contributing to distinctive side effect profiles such as motor fluctuations injection-related discomfort nausea drowsiness hypotonia dyskinesia and morning akinesia. Within this context sublingual administration specifically through tablets emerges as a promising alternative. Bypassing hepatic and gastrointestinal pathways sublingual administration facilitates direct entry into systemic circulation potentially alleviating certain side effects associated with traditional routes. This review article comprehensively explores the multifaceted nature of Parkinsons disease treatment and critically evaluates the potential advantages of sublingual administration in overcoming specific challenges encountered with conventional therapeutic approaches. By developing into the intricacies of different administration routes and their associated side effect profiles this review aims to provide a nuanced understanding of the complexities involved in managing Parkinsons disease. The focus on sublingual administration as a direct and efficient pathway underscores its potential to reduce side effects and enhance overall treatment efficacy offering a novel perspective on optimizing therapeutic strategies for this intricate neurodegenerative disorder.
Advancing Wound Management: A Comparative Study of Mechanical Fixation and Platelet-Rich Plasma in Split Skin Grafting
Authors: K R Sneha , S Paul Ashwini
Published: August 2024

Background and aim Platelet-Rich Plasma PRP emerges as an autologous derivative obtained from whole blood via gradient density centrifugation. Following skin graft reconstruction the duration of the healing process varies and can pose challenges contingent upon factors such as wound site size of skin defect and patient comorbidities. The significance of PRP lies in its capacity to integrate elevated concentrations of platelet-derived growth factors into the skin graft. Given the financial constraints limiting access to commercially available recombinant platelet-rich plasma for skin grafts this study employed platelet extract sourced from the patients own blood to explore and illustrate the therapeutic potential of PRP in skin graft procedures. The objective of this randomized prospective study was to assess the efficacy of PRP in skin grafts compared to conventional methods such as sutures staplers or adhesive agents.Methods The data were sourced from patients admitted as inpatients for wound management at the Department of General Surgery Akash Hospital Devanahalli spanning from January 2023 to January 2024. A total of 60 patients were included in the study with 30 cases randomly assigned to receive autologous platelet-rich plasma and 30 cases receiving conventional methods such as staples or sutures to secure the skin grafts in a control group.Results Autologous PRP demonstrated accelerated and improved healing rates. Instant graft adherence was observed in all cases within the PRP study group. Incidences of hematoma graft edema discharge from the graft site frequency of dressings and hospital stay duration were significantly lower in the PRP group. Furthermore no adverse effects or reactions were noted with the use of autologous PRP among the study participants.Conclusion The integration of PRP with Split Thickness Skin Graft STSG yielded significant enhancements in clinical outcomes and reduced the duration of wound healing. Consequently this treatment amalgamation offers a promising avenue for expediting skin recovery following skin graft reconstruction with minimal downtime. Our findings underscore its manifold benefits to both patients and surgeons affirming its high utility and efficacy.
Activation mechanism and novel binding sites of the BKCachannel activator CTIBD
Authors: Lee Narasaem , Kim Subin , Lee Na Young , Jo Heeji , Jeong Pyeonghwa , Pagire Haushabhau S , Pagire Suvarna H , Ahn Jin Hee , Jin Mi Sun , Park Chul-Seung
Published: August 2024

The large-conductance calcium-activated potassium (BKCa) channel, which is crucial for urinary bladder smooth muscle relaxation, is a potential target for overactive bladder treatment. Our prior work unveiled CTIBD as a promising BKCachannel activator, alteringV1/2andGmax. This study investigates CTIBD’s activation mechanism, revealing its independence from the Ca2+and membrane voltage sensing of the BKCachannel. Cryo-electron microscopy disclosed that two CTIBD molecules bind to hydrophobic regions on the extracellular side of the lipid bilayer. Key residues (W22, W203, and F266) are important for CTIBD binding, and their replacement with alanine reduces CTIBD-mediated channel activation. The triple-mutant (W22A/W203A/F266A) channel showed the smallestV1/2shift with a minimal impact on activation and deactivation kinetics by CTIBD. At the single-channel level, CTIBD treatment was much less effective at increasingPoin the triple mutant, mainly because of a drastically increased dissociation rate compared with the WT. These findings highlight CTIBD’s mechanism, offering crucial insights for developing small-molecule treatments for BKCa-related pathophysiological conditions.
Special Tribute
Authors: Pantic Katarina
Published: August 2024

This tribute, written by Katarina Pantic, ISfTE Communication Officer, honors Dr. Megan Hamilton, a dedicated scholar who embraced her Anishinaabe heritage and focused her career on promoting Indigenous education. Known for her creativity and mentorship, Megan inspired students by sharing her journey and encouraging them to pursue their dreams. Her work, including a notable dissertation on Montana’s Indian Education for All resources, reflects her commitment to Indigenous ways of knowing. As we remember Megan, we are reminded to live with humility, honesty, respect, and love, values she held dear.
Fastener and rail surface defects detection with deep learning techniques
Authors: Yilmazer Merve , Karakose Mehmet
Published: August 2024

The railways, which are frequently used by countries for both passenger and freight transportation, should be checked periodically. Controls made with classical methods are slow and there are often overlooked faults.  This work suggests a novel deep learning-based technique for identifying fastener and railway track surface defects. Within the scope of the proposed method, firstly,  The railroad track was observed using an autonomous drone. Shaky images in the recorded video were removed with a video stabilization algorithm. Frames were created and labeled from the video and rail and fastener regions were detected using the Faster R-CNN deep neural network. Fault detection was performed through ResNet101v2-based classification using different datasets for  identifying surface detects in rails and different datasets for detection of fasteners. The proposed method was experimentally shown to have a 98% accuracy rate for detecting rail surface flaws and a 95% accuracy rate for detecting fastener flaws. An user interface was developed to display the identified faulty images on computers, tablets and mobile phones via a mobile application. The system, which was previously proposed in a different study, was retrained by going through the video stabilization step, thus improving the fault detection rate, and the method was also included in the user interface module.  This study contributes to the processing of ever-increasing video data with deep learning-based methods. It is also anticipated that it will benefit researchers working in the field of railway non-contact fault detection.
Empirical study of 3D-HPE on HOI4D egocentric vision dataset based on deep learning
Authors: Le Van Hung
Published: August 2024

3D hand pose estimation (3D-HPE) is one of the tasks performed on data obtained from egocentric vision camera (EVC) such as hand detection, segmentation, and gesture recognition applied in fields such as HCI, HRI, VR, AR, Healthcare, supporting for the visually impaired people, etc. In these applications, hand point cloud data obtained from EV is not very challenging due to being obscured by gaze direction and other objects. Our paper performs a comparative study on 3D right-hand pose estimation (3D-R-HPE) from the HOI4D dataset with four cameras used to collect and animate the dataset. This is a very challenging dataset and was published at CVPR 2022. We use CNNs (P2PR PointNet, Hand PointNet, V2V-PoseNet, and HandFoldingNet - HFNet) to fine-tune the 3D-HPE model based on the point cloud data (PCD) of hand. The resulting error of 3D-HPE is presented as follows: P2PR PointNet (average error (Erra) is 32.71mm), Hand PointNet (average error (Erra) is 35.12mm), V2V-PoseNet (average error (Erra) is 26.32mm), and HFNet (average error (Erra) is 20.49mm). HFNet is the latest CNN (in 2021) with the best results. This estimation error is small and can be applied and modeled to automatically detect, estimate, and recognize hand pose from the data obtained by EV. The average processing time is 5.4fps when done on the GPU of the HFNet, which is the fastest. Detailed quantitative and qualitative results were presented that are beneficial to various applications such as human-computer interaction, virtual and augmented reality, and healthcare, particularly in challenging scenarios involving occlusions and complex datasets.
AI-Driven Analysis: Optimizing Tertiary Education Policy through Machine Learning Insights
Authors: Sy Christian Y , Maceda Lany L , Abisado Mideth B
Published: August 2024

Tertiary education is pivotal in equipping individuals with the necessary knowledge and skills for success, prompting global initiatives for equitable access to quality higher education. The Philippines' Universal Access to Quality Tertiary Education (UAQTE) Act exemplifies this commitment by providing free tertiary education to eligible Filipino students. This study evaluates the UAQTE program's implementation through the perspectives of student beneficiaries, employing a combined approach of qualitative analysis and machine learning techniques. The study utilizes supervised and unsupervised machine learning to analyze student responses, specifically multiclass text classification using BERT and topic modeling with BERTopic. The results reveal insights into students' experiences and perceptions of the UAQTE program. While BERT demonstrates effectiveness in certain categories, challenges such as overfitting and balancing sequence length versus model performance are identified. BERTopic highlights the importance of capturing two-word combinations for enhancing topic coherence. Key themes identified through both approaches include "Educational Opportunity," "Program Implementation," "Financial Support," and "Appreciation and Gratitude," emphasizing their significance within the UAQTE program. Alignment between machine learning analyses and domain experts' insights underscores the relevance and effectiveness of the methodologies employed. Recommendations for optimizing the UAQTE program include refining focus areas, strengthening support systems, incorporating two-word combinations in analysis, and fostering continuous monitoring and interdisciplinary collaboration. By leveraging insights from qualitative and machine learning analyses, administrators can make informed decisions to enhance program effectiveness and comprehensively address students' diverse needs.
“Quem Trouxe a Moda do Travesti para o Brasil”?: teatros, hormônios e subjetividades (1950-1960)
Authors: Souza Paulo Vitor Guedes de
Published: August 2024

Este artigo é sobre históricas possibilidades subjetivas do/no universo das travestilidades entre as décadas de 1950 e 1960. Como anunciado no título, a questão central é indagar e problematizar “‘Quem trouxe a moda do Travesti para o Brasil’?” Essa questão nasce de uma reflexão referente ao título de uma matéria presente na edição 75 da Revista Manchete (RJ), com data de publicação do dia 26 de setembro e, que apresenta Ivaná como peça central, esse, um importante e famoso artista transformista do período no Brasil. A partir da indagação será criada a possibilidade de pensar e questionar o fenômeno reconhecido como travestilidades no espaço dos palcos dos teatros e a emergência de uma nova subjetividade travesti forjada a partir de modificações estéticas-corporais por meio da ingestão de hormônios. Logo, indago, o que seria uma “moda do travesti” – como proposto pela revista mencionada. Algo passageiro? Seria esse o sentido oferecido pela imprensa? Talvez sim. Contudo, saliento que, para além dos hormônios, redes de amizade constituídas em espaços de sociabilidade como boates e teatros foram de grande importância para a constituição de desejos, trocas, sonhos, negociações que possibilitaram a emergência das históricas subjetividades travestis durante o decorrer das décadas de 1950 e 1960.
Rehabilitation of an Upper Extremity Weight-Bearing Athlete with an Ulnar Collateral Ligament Injury: A Case Report
Authors: Corbitt Annemieke D. , Bandy William D.
Published: August 2024

Background and Purpose

Ulnar collateral ligament (UCL) injury is a common elbow injury among overhead athletes, particularly baseball pitchers. However, limited research exists for non-throwing athletes, especially regarding rehabilitation. The purpose of this case report is to illustrate the use of early weight-bearing activities into the rehabilitation protocol for non-operative management of athletes with a UCL injury.

Case Description

The subject was a 17-year-old female competitive cheerleader. Two weeks prior, during the performance of an acrobatic skill in which she transitioned to full upper extremity (UE) weight-bearing, she sustained an injury to her right elbow. Physical therapy examination findings indicated a diagnosis of a UCL sprain. Self-reported outcome measures revealed a FOTO score of 69/100 and a Quick Dash score of 43/100. The subject attended 14 therapy sessions over nine weeks to address physical function and performance, which were assessed at intervals during her therapy program. Rehabilitation consisted of therapeutic exercise for the progression of UE functional weight-bearing including planks, ball push-ups, handstands, crab walks, stool pulls, handstand walks, and UE plyometric jumps.

Outcomes

Along with documented improvement of the standard musculoskeletal examination measures of range of motion, strength, and functional performance, the subject demonstrated no elbow instability and improved FOTO and Quick Dash scores of 98 and 0, respectively. The subject demonstrated 105% limb symmetry index with the return to sport (RTS) UE functional testing of one-armed seated shot-put throw (SSPT) and achieved normative values with the closed kinetic chain upper extremity stability test (CKCUEST).

Conclusion

This case report highlights the successful treatment of a subject with a UCL injury and the integration of therapy interventions with a focus on UE weight-bearing. Further research on performing high level UE weight-bearing activities during rehabilitation and RTS guidelines is needed.
Point of Care Ultrasound Guided Management of Lateral Ankle Sprains: A Case Series
Authors: Bush Matthew , Umlauf Jon , Pickens Bryan
Published: August 2024

Background

Lateral ankle sprain (LAS) is a common injury with incidence rates reported at 7.2 per 1000 person-years. Physical examination strategies provide limited information to guide rehabilitation that can maximize clinical outcomes. Early and accurate diagnostic information using ultrasound imaging enables individualized care and the ability to monitor healing along with its response to activity and rehabilitation.

Purpose

The purpose of this study was to describe and observe the outcomes associated with Point of Care Ultrasound (POCUS) guided early management of acute and sub-acute lateral ankle sprains.

Study Design

Case series

Methods

Individuals with a LAS within the prior 28 days underwent a clinical evaluation to include a POCUS exam to assess ligamentous integrity. Objective and POCUS findings were integrated to classify each LAS into one of four categories. Each grade of ankle sprain corresponded to levels of bracing for the protection of injured structures with each patient receiving physical therapy care based on rehabilitation guidelines. Participants completed the Foot and Ankle Ability Measure (FAAM) activities of daily living and Sports subscale, the Foot and Ankle Outcome Score (FAOS), Patient Reported Outcomes Measurement Information Systems Global Health, Tampa Scale of Kinesiophobia (TSK-11), Cumberland Ankle Instability Tool (CAIT), and the Numeric Pain Rating Scale as well as the Ankle Lunge Test and Figure 8 measurements at baseline, 4 weeks, 8 weeks and 12 weeks post enrollment. The FAAM Sport subscale, all FAOS subscales, and the TSK-11 were also collected at 24 weeks while the CAIT was collected at baseline and 24 weeks.

Results

Fourteen participants were enrolled with 11 participants completing all data collection. FAAM Sport scores significantly improved at 4, 8, 12 and 24 weeks. All components of the FAOS significantly increased except for Sport scores at four weeks and Quality of Life scores at four and eight weeks.

Conclusion

POCUS guided early management and ligamentous protection of LASs resulted in significant short and long-term improvement in function and return to sporting activity. This case series highlights the feasibility of using ultrasound imaging to assess the severity of ligamentous injury and align bracing strategies for ligamentous protection. The observations from this case series suggest that functional bracing strategies focused on ligamentous protection to promote healing and reduce re-injury rates does not delay improvement in functional outcomes.

Level of Evidence

Level IV, Case Series
exilio en Primavera con una esquina rota
Authors: Blanco David
Published: August 2024

En el presente artículo resalto la necesidad de reconocer el exilio como una grave y autónoma violación de los derechos humanos que no puede ser obviada en los contextos transicionales. Con ese objetivo, recupero la obra de Mario Benedetti Primavera con una esquina rota y, con base en ella, describo las diferentes dimensiones de la vida que se ven afectadas por el exilio. Algunas de esas dimensiones relativas al daño que provoca el exilio suelen opacarse con el discurso jurídico. De ahí la importancia de propiciar la reflexión a partir de la literatura, para poder ver aquello que el discurso y la teoría jurídica no permiten apreciar. Asimismo, aludo a los tópicos cruzados entre la narrativa y la poesía que justifican el lugar que debe ocupar el exilio en la transición, con lapretensión última de intentar apreciar mejor el fenómeno.
El aprendizaje del lenguaje, un motor de desarrollo revisión sistemática de literatura
Authors: Sacoto Fernanda , Guillen Verónica M. , Hevia Artime Isabel
Published: August 2024

El desarrollo del lenguaje es fundamental para los seres humanos ya que este componente desempeña funciones de especial relevancia a nivel cognitivo, social y cultural, ya que permite que los individuos puedan expresar intenciones, estabilizarlas y convertirlas en acciones (Ríos, 2020, p. 3). Por tanto, cuando se presentan factores que ponen en riesgo el desarrollo del lenguaje, es necesario implementar tratamientos e inclusive políticas públicas para mejorar las habilidades lingüísticas de las personas. 
Pese a que se han llevado a cabo diferentes formas de intervención para la inserción de las personas sordas con la comunidad oral, esto no se ha logrado en su totalidad, según lo menciona la Federación Mundial de Sordos en su postura respecto a los derechos lingüísticos; de ahí que en la actualidad, se estén generando acercamientos con visión sociocultural para permitir que las personas sordas utilicen la lengua de señas como base para el aprendizaje de otras habilidades lingüísticas, como la lectura y escritura de lenguajes orales.
En este sentido, para determinar las experiencias y resultados alcanzados en estos procesos de aprendizaje de un lenguaje oral al utilizar la lengua de señas como eje, hemos ejecutado una revisión sistemática de la literatura basada en el método presentado por Kitchenham (2004). La revisión se trazó en tres (3) etapas: planificación, selección y resultados. Asimismo, se vinculó a secciones o temas estructurados en el método Preferred Reporting Items for Systematic reviews and meta-analyses- PRISMA.
Beyond the Classroom: The Power of Websites for Engaging and Effective Math Education
Authors: Mendoza Loor Eddy Gregorio , Huerta Vera José Fernando , Intriago Alonzo Flora Antonia , Ávila Martínez María Fabiola
Published: August 2024

Technology in current education is essential for the development and optimization of teaching-learning processes, so having tools and methods that allow the implementation of these technologies is an important factor to develop adequate planning and teaching tools. The objective of this research was to develop a website, using the WebNode tool, that contributes to mathematics teaching at the university preparatory level. Through a bibliographic review and application of interviews, the minimum thematic contents of the subject were established. It was necessary to design and develop a website that would allow the curricular planning of the subject to be articulated, pedagogical tools and activities so that students have support that facilitates the learning of the subject of mathematics through the integration of ICT.
Fraud Disclosure: A Systematic Literature Review Approach
Authors: Putri Novia Septiana , Saifudin Saifudin , Trilestari Rr.Dian Indriana
Published: August 2024

Financial fraud is an issue of increasing concern in various sectors, especially in the context of companies and financial institutions. This article aims to explore the published literature on fraud disclosure. Using a systematic literature review approach, this article aims to identify, assess, and synthesize previous research results related to this topic. The systematic literature review approach allows researchers to follow a structured procedure in searching, selecting, and analyzing relevant literature. This process includes searching major academic databases, using specific keywords, and applying strict inclusion and exclusion criteria. The result of this process is a collection of the most relevant and high-quality studies that provide deep insights into the topic of fraud disclosure. This article identifies several key themes in the literature on fraud disclosure. First, there are various methods and techniques used to detect and report fraud, including Forensic Audit; Audit Investigation; Auditor Competence. Second, the article highlights the importance of transparency and responsibility in the fraud disclosure process, as well as the role of regulators and oversight bodies in overseeing this practice. Third, factors such as Forensic Auditing; Investigative Auditing; Auditor Competence also influence the extent to which and how fraud is disclosed. In addition, this article identifies some of the challenges faced in research on fraud disclosure, including data limitations, difficulties in measuring the effectiveness of various disclosure methods, and variability in applicable regulations. The conclusion of this review emphasizes the need for further research to develop a more comprehensive and effective framework for addressing fraud, as well as the importance of collaboration between academics, practitioners, and regulators to improve fraud disclosure practices.
Afiliasi Politik Dewan Komisaris dan Direksi Terhadap Pengungkapan Tanggung Jawab Sosial Perusahaan
Authors: Nurhandika Arief , Fitriani Chintia , Teguh Iman , Rahimi Faishal
Published: August 2024

Tujuan penelitian ini untuk menguji pengaruh afiliasi politik pada dewan komisaris dan afiliasi politik direktur terhadap skor CSR. Penelitian ini merupakan peneltian kuantitatif menggunakan purposive sampling method dalam pengambilan sampelnya.  Sampel penelitian ini adalah Indonesia Stock Exchange Industrial Classification sektor D yaitu consumer non-cyclicals dari periode 2017-2022. Penelitian ini mengguanakan analisis regresi data panel. Peneltian ini menggunakan software STATA untuk analisis statistik. Populasi yang digunakan sebesar 17 perusahaan dan di dapat 102 sampel observasi untuk dianalisis. Hasil penelitian menemukan bahwa dewan komisaris yang berafiliasi politik berpengaruh positif terhadap skor CSR. Namun pada variabel dewan direksi yang berafiliasi politik tidak berpengaruh terhadap skor CSR. Implikasi pada penelitian ini memberikan gambaran bagaimana perusahaan atau praktisi menyikapi koneksi politik dapat selaras dengan tingkat nilai CSR dengan memperhatikan keadaan sosial seperti terjadinya covid-19, pemilu, dan hal lain yang menyangkut aturan - aturan baru pemerintah tentang pertanggungjawaban sosial. Penelitian ini tidak menutup kemungkinan adanya kekurangan pertama adalah data yang diambil masih pada satu sektor saja mungkin penelitian selanjutnya menggunakan sektor lain agar mampu menggambarkan keadaan disektor lain atau sebagai pembanding, kedua penelitian ini masih pada dua vaiabel independen yang belum mencerminkan keseluruhan koneksi politik mungkin penelitian selanjutnya menambahkan lebih spesifik koneksi politik seperti militer dan mantan menteri.