bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing efficacy and safety of rectally vs. intravenously administered Sibazon in treatment of generalized epileptic seizures in children
Authors: Prityko A. G. , Osipova K. V. , Sokolov P. L. , Ezhova E. A. , Kotel’nikova I. G. , Lukyanov E. G. , Osipova G. A.
Published: October 2021

Objective: to prove the therapeutic equivalence and similar safety profile of “Sibazon, rectal solution” (international nonproprietary name: diazepam) and “Sibazon, solution for intravenous and intramuscular administration” in children with primary generalized and bilateral tonic, clonic and tonic-clonic seizures.Material and methods. An open-label, randomized clinical trial on efficacy and safety was conducted in 20 patients suffering from epilepsy with generalized seizures aged 1 to 17 years. Clinical blood and urine tests, biochemical blood analysis were used for diagnostics (glucose, total protein, albumin, total bilirubin, cholesterol, aspartate aminotransferase, alanine aminotransferase, creatine phosphokinase, alkaline phosphatase, creatinine, urea, creatinine clearance), as well as data on electrocardiographic (ECG) and electroencephalographic (EEG) studies. The patients were divided into two groups: in Group 1 (n=8), a rectal solution was used, in Group 2 (n=12) – a solution for intravenous and intramuscular administration.Results. The number of cases in which seizures were completed within 10 minutes after using the drug without resuming within subsequent 60 minutes, in Group 1 was 7 (87.5%), and in Group 2 – 9 (75.0%) (Fisher exact test (FET): p=0.617). Repeated primary generalized or bilateral tonic/clonic/tonic-clonic seizures within 24 hours after drug administration, in Group 1 were absent in 5 (62.5%) patients, in Group 2 – in 6 (50%) (FET: p=0.670); within 48 hours after drug administration – in 5 (62.5%) and 7 (58.3%) children, respectively (FET: p=1.00). Physical examination revealed no pathology in all patients at the final visit. While comparing ECG and EEG data at the final visit, no inter-group differences were found by the number of children with deviations from the norm. The results of laboratory studies confirmed that using the studied drugs had no negative effect on the main indicators of clinical and biochemical blood tests as well as clinical urine analysis.Conclusion. The effectiveness of the rectal form of Sibazon in relieving pediatric generalized epileptic seizures is comparable to that of Sibazon for intramuscular administration. The drug rectal form, due to easy-to-use administration, is preferable for outpatient practice. “Sibazon, rectal solution” is safe and has good tolerability.
Treatment of epilepsy associated with primary and metastatic brain tumors
Authors: Lebedeva A V. , Burd S. G. , Vlasov P. N. , Ermolenko N. A. , Zhidkova I. A. , Zyryanov S. K. , Kovaleva I. Yu. , Naskhletashvili D. R. , Perunova N. Yu. , Rudakova I. G. , Shikhkerimov R. K. , Yamin M. A.
Published: October 2021

There is a number of unsolved issues in management of epilepsy associated with primary and metastatic brain tumors (BTs). In particular, no consensus approaches to treatment of patients with epilepsy associated with BTs have been proposed regarding use of current anti-epileptic drugs (AEDs). The review presents the relevant data on epidemiology, features of clinically manifested epilepsy at varying stages of BTs, aspects of drug-drug interaction between AEDs and anti-tumor agents, AED-related effects on cognitive functions as well as quality of life in patients with epilepsy associated with BTs. Levetiracetam and valproic acid comprise the first-line drugs for treating seizures in patients with BTs. It is unreasonable to use AEDs acting as hepatic microsomal enzyme inducers for therapy of epileptic seizures in BTs, because it may decrease efficacy of chemotherapy agents and glucocorticoids along with elevated rate of side effects. Perampanel acting as a selective noncompetitive AMPA receptor antagonist, may be one of the drugs of choice for the adjunctive therapy of epileptic seizures associated with BTs.
Igor Dmitrievich Stulin
Authors: Editorial Article
Published: October 2021

.
The Issues of Construction and Analysis of Ordered Partial Correlation Networks in Psychological Research
Authors: Artemenkov S.L.
Published: October 2021

In the context of network modeling, psychological variables are understood as directly affecting each other, and not as a consequence of latent constructs. An efficient assessment of networks showing relationships between measured variables can be carried out using the methods of regularization of the network of partial correlations. This article provides an example of constructing a regularized network of partial correlations in the R software environment (it is showing the relationship between the personality traits of adolescents and their behavior in virtual space using the example of the social network VKontakte) and examines the features of constructing and analyzing ordered networks of partial correlations. A list of potential problems arising when using the considered network methodology is presented. The issues related to sample size and reproducibility of the network, difficulties in interpreting networks, and comparing different networks with each other, including both network models and models of latent variables, are considered.
Current methods of the diagnosis and treatment of intracranial otogenic and rhinogenic complications
Authors: Serebryakova S. N. , Petushkov E. V. , Dovgalyuk A. Y. , Firsov P. D. , Klyushkin I. V. , Ibatullin M. M.
Published: October 2021

On the basis of the archival material of the Kazan otolaryngologic clinic, the comparative analysis of intracra-nial rhinogenic and otogenic pathology is performed by stages. In the presence of a general decrease of the intracranial complications rate during the last 20 years in this pathology structure the combined lesions prevail, which determines the high level of lethality. Computer tomography and particularly MRT-tomography allow to reveal the infection focus in the skull cavity and to define the adequate surgical tactics.
About nitrogen metabolism with a lacto-vegetable diet
Authors: Volovik A. B.
Published: October 2021

In one of our reports, we were able to show that a milk diet, which does not satisfy the energy needs of scarlet fever patients, leads to a negative nitrogen balance. Since in the milk diet, along with a moderate content of protein and fat, there were extremely few carbohydrates, it was natural to assume that an increase in the amount of the latter could have a significant effect on protein metabolism. To replenish food with carbohydrates, we included in the diet, in addition to milk, vegetable purees, cereals, jelly. The menu was composed in such a way that for breakfast and dinner, patients were given porridge with milk, and for lunch, vegetable puree and cranberry jelly. In addition, children received 200 grams twice a day. milk as a drink. The well-known schematization of dishes was carried out in order to facilitate the technical conditions of work. According to a preliminary calculation, the total caloric value of our lacto-vegetable diet was 2086 calories, with a content of 56 grams in food. squirrel, 294 gr. carbohydrates and 70 gr. fat. Of the 10 children put on this menu, only one 12-year-old patient with a mild form of scarlet fever ate the whole food offered to him, while the rest of the children were content with more or less of the dishes they were given. Patients aged 4-5 years drank an average of 600-700 grams. milk and ate 150-300 gr. porridge, 75-150 gr. mashed potatoes and 150-200 gr. jelly; older children ate 400-500 grams. porridge, 150-300 gr. puree, 250-300 gr. jelly and about 800 gr. milk.
Frank, Ludwig. Die psychokathartische Behandlung nervöser Störungen. (Psychoneurosen-Thymopathieri). Verlag Georg Thieme. Leipzig. 1927. IV + 208
Authors: Galant I.
Published: October 2021

Frank proposes to call psychoneuroses thymopathies, because psychoneuroses and all related diseases are disorders of the affective sphere of a quite definite nature. These are dynamic disorders of affective life, consisting mainly in the phenomena of the repression of affects, their accumulation and accumulation in the subconscious, their desire to move from the subconscious to the superconscious and the delay of this process due to the "internal resistance" (innerer Widerstand), displacing those striving for the release of affects back into the subconscious. With regard to the treatment of such dynamic disorders of the affective sphere, Frank considers psycho-cathartic treatment to be the most appropriate. The active principle of psychocatarsis is the awareness and secondary experience of affective excitations accumulated for various reasons in the subconscious. This is achieved in a hypnotic state of half-sleep, when the consciousness is narrowed only so much that the internal resistance falls, the delays disappear and there is a free reaction of the affects accumulated in the subconscious with the passive participation of superconscious attention. Having responded to the restrained affects and realizing those initial experiences with which painful symptoms are associated, the b-oh recovers.
To the question of the influence of experimental inflammation on the content of K, Ca and water in the skin of rabbits
Authors: Dmitriev A.
Published: October 2021

E. Nathan and F. Stern (Dermat. Ztschr., Bd. 55, H. 1), as a result of intense illumination of the skin of rabbits with ultraviolet rays, an increased content of Ca was observed in the areas of inflamed skin, the amount of water at the beginning of inflammation increased, by the end of inflammation it decreased. By the end of the inflammation, the K content in these areas increased under low illumination with the same rays. The content of Ca and water was the same as in the case of intense irradiation, but an increase in the content of K was noted already from the onset of inflammation. The changes in the skin of rabbits after irritation with mustard oil were in general the same as when they were irradiated with light.
Therapy for patients with high blood pressure
Authors: Raysky S. M.
Published: October 2021

E. Zak (Die rztliche Praxis, No. 7, 1929) attaches great importance to mental influences and therefore suggests doctors to be careful in the sense of using terms such as "arteriosclerosis" or "angina pectoris" in front of some patients. Further, making the division of high blood pressure into two groups (stable and labile), the author proposes the following measures: for stable high blood pressure, caffeine in powder or in the form of coffee (for headaches), warns against pyramidon on a lean stomach and recommends well sometimes acting Aleuthan (Pyramiden + papaverin). The food of such patients should be poor in proteins, meat, spices and NaCl. Instead of NaCl, the author proposes a dietary salt (Dit-Salz, consisting of 1-2 g. NaCl and 2-4 g. KCl).
The importance of calcium in the treatment of heart disease
Authors: Raysky S. M.
Published: October 2021

Prof. G. Singer (Die rztliche Praxis, No. 5, 1929. Medizinisches Seminar) expresses itself in the sense that in some heart diseases with congestion both in the large and in the small circle (mainly with myodegenerations of the heart and aortic defects), when heart and diuretics do not work, - very often they achieve good results by introducing into the body simultaneously with digitalis (intravenously or per os) 10% calcium solution in the amount of 1 snt. 3 exclusively intravenously. Calcium, enhancing the effect of digitalis on the heart, at the same time moderates its side effects on the parasympathetic system and, according to the author, is a whip and reins for the digitalis (Die Peitsche und der Zgel).
To stop bleeding from soft tissues of wounds during trepanation
Authors: Tsimkhes I.
Published: October 2021

In case of bleeding from wounds or incisions of the soft tissues of the head E. Makai (Zentrlbl. F. Chir. 1929, No. 37) applies Michel's brackets to the thickness of the wound wall so that skin is captured on one side, and aponeurosis on the other.
On the function of the anastomosis between the small and large intestines
Authors: Tsimkhes I.
Published: October 2021

Tnnis (Dtsch. Z. f. Chir. Bd. 212. 1928) notes that in chronic obstipation the function of the anastomosis of the small intestine with the large intestine plays an important role. Often, due to antiperistaltic movements of the large intestine, the contents of the intestines can return or linger in the small intestine, making it difficult to empty the small intestine. The author recommends, based on the above considerations, to impose anastomosis end-to-side or end-to-end.
Histological diagnosis of the luetic placenta
Authors: Dmitriev A.
Published: October 2021

Kaufmann (Derm. Ztschr. Bd. 56, H. 5.29), examining histologically the placenta of mothers with syphilis, as well as the umbilical cord, thinks that with the nonspecific morphological changes of syph. placenta examination of umbilical cord tissue for the presence of sp. pal. gains in importance. The detection of spirochetes in organ pieces is purely scientific, but not practical. A. gives a detailed picture of changes in the syphilitic placenta and umbilical cord.
To the question of the action of salvarsan preparations
Authors: Dmitriev A.
Published: October 2021

Szeutkirlye (Derm. Ztschr., Bd. 56, H. 2/3, 29) used various solutions of myosalvarsan, injecting them at the sites of manifestations of lues I and II under the skin near efflorescence. It turned out that strong solutions (up to 15%) of this drug, injected locally, do not have their strong killing effect on pale spirochetes. When using neosalvarsan at the same time intravenously, the spirochetes disappeared after 24 hours.
Psychotherapy of schizophrenia and its borderline states E. Kretschmer (Zeitschr. F. D. Ges. Neur. U. Psych. Bd. 121)
Authors: Andreev M.
Published: October 2021

Schizophrenia is a hereditary, endogenous disease. The unfounded fatalism associated with the concept of the endogenous, the constitutional has long paralyzed our therapeutic thinking. And in schizophrenia "we often saw incurable defects where there were only bizarre psychogenic arabesques of deceptive schizophrenia of symptoms against the background of a relatively unsharp process." For a psychiatrist, as a practical therapist, and from the point of view of an endogenous understanding of schizophrenia, it is important to be interested in not what is endogenously destroyed, but what is recoverable and in what form. In psychotherapy for schizophrenia, its features depend on the characteristics of the period and degree of the disease.
Meeting of the Russian Endocrinological Society on October 10, 1929 (Moscow)
Authors: Ginzburg E.
Published: October 2021

The first meeting of the Russian Endocrinological Society in the new 1929-30 academic year was opened with the reports of V. Ye. Krasheninnikov "On the problem of endocrine therapy of cancerous tumors" and prof. D. M. Rossiyskiy "Syphilis of the endocrine apparatus." the present time is almost non-existent.
To the clinic and X-ray diagnostics Inïçrposiïo colonis
Authors: Goldstein M. I.
Published: October 2021

The unusual arrangement of the swollen loops of the large intestine between the liver and the diaphragm, the so-called. interpositio colonis, recently more and more attracts the attention of clinicians and radiologists, due to the complex symptom complex, clinical course and pathogenesis of this disease (Bclre, Chilaiditi, Perussia, Jaricaud, Huguet, Podkaminsky, Uspensky, etc.).
Significance of the Sachs-Witebsky cytochol reaction for serodiagnosis of syphilis
Authors: Tselischevaya A. D. , Mirkina M. I.
Published: October 2021

Serology of syphilis, which has a relatively recent past (since 1907), in recent years has written into its pages a number of huge successes, which greatly facilitated the diagnosis of syphilis. Serology of syphilis owes such success to the so-called groove. flocculation reactions, the number of which is increasing every year, since despite the great successes in this area, still no other reaction has been proposed, in 100% of cases positive at different stages of syphilis and not possessing a groove. nonspecificity, i.e. the ability to give a positive result in the absence of syphilis.
More about neosalvarsan for anthrax
Authors: Sitepukhovich D. M.
Published: October 2021

There are currently two specific treatments for anthrax. Specific serum and neosalvarsan.
Combined treatment of pneumonia with calcium and digitalis Hellmann (Med. Kl. 1932, No. 39)
Authors: Kramov N.
Published: October 2021

Hellmann describes (Med. Kl. 1932, No. 39) the results of 10 years of experience with the use of calcium chloride and digitalis in cases of protracted pneumonia or complicated by pulmonary edema.
Pregnancy and tuberculosis Levy-Lѳnz (Z. f. D. G. Tub. Z. H. 11)
Authors: Kramov N.
Published: October 2021

Levy-Lѳnz (Z. f. D. G. Tub. Z. H. 11), - considering pregnancy an unfavorable factor in the course of pulmonary TB, sees in artificial interruption not a remedy, but only liberation from the harmful influence b.
Miliary tuberculosis accidentally discovered at autopsy Deelman (Z. 1.d.g. Tub. 36, H. 11)
Authors: Kramov N.
Published: October 2021

Deelman reports (Z. 1. d. G. Tub. 36, H. 11) about 3 cases of miliary tbc, unexpectedly found at autopsy.
Artificial pneumothorax — long-term results. Veran (Presse Med. No. 10, 1932)
Authors: Kramov N.
Published: October 2021

Veran (Presse Med. No. 10, 1932) examined 226 cases of pt. In 60% pt was discontinued for medical reasons.
Cancer of the larynx Tapia (The Journ.of Laryngol.otolog. 1931)
Authors: Trutnev A.
Published: October 2021

Tapia (ibid.) Saw 993 cases of laryngeal cancer in 28 years
Chronicle. Volume 32, No. 10-11 (1932)
Authors: Board Editorial
Published: October 2021

About the All-Union Institute of Experimental Medicine. (Resolution of the Council of People's Commissars of the USSR). October 15, 1932
Impressions of the interdepartmental expedition to study Urov disease and goiter in August-October 1932
Authors: Reshetnikov S. A.
Published: October 2021

The problem of Trans-Baikal endemic polyarthritis or Kashin-Beck's disease, and in the language of the local population of the Urovka disease, is so urgent that the organs of the People's Commissariat of Agriculture, the People's Commissariat of Heavy Industry, the People's Commissariat of Railways, Tsustrakh and other branches of the national economy and industry are interested in studying it.
Protoplasmodynamic moments in the clinic of cardiovascular patients
Authors: Malkin Z. I.
Published: October 2021

In search of a satisfactory explanation of the pathogenesis of heart failure, the clinic has not been satisfied for a long time with one account of changes in the contractility of the heart muscle and changes in valves, but turns its attention to peripheral circulation.
Hemangioma of the small intestine in a child
Authors: Grebnev P. N. , Mustafin Ya. M. , Osipov D. V.
Published: October 2021

Small intestinal hemangiomas in surgical patients with diseases of the gastrointestinal tract occur in only 0.009% of cases. Intestinal bleeding is often the first and only sign of a disease that is asymptomatic for a long time. This pathology is also extremely difficult to diagnose.
Psychophysiological characteristics of victims of accidents in agriculture
Authors: Nushtaev I. A.
Published: October 2021

The results of multidimensional analysis of traumatism cases in agriculture are presented. The basic causes of dangerous situations and accidents in production are revealed. The significance of accident prevention, in particular, the study of psychophysiologic features of victims with subsequent professiogram preparation for basic types of activity in agriculture is emphasized.
On the 12th anniversary of the Autonomous Tatar Socialist Soviet Republic
Authors: Board Editorial
Published: October 2021

"The Presidium of the All-Russian Central Executive Committee decides to authorize the Revolutionary Committee of the Autonomous Tatar Soviet Republic to start from June 25 this year in the dispatch of the duties assigned to it by the resolution of the All-Russian Central Executive Committee and the Council of People's Commissars dated May 27 this year on the Autonomous Tatar Soviet Republic." This was in 1920.
World Spartakiad, tasks of health authorities for the World Spartakiad
Authors: Ivanovsky B. A.
Published: October 2021

The physical culture movement had the great honor of celebrating with its grandiose holiday the successful completion of the five-year plan in four years and the completion of the construction of the foundation of socialism in the USSR by the working people of the Soviet Union under the leadership of the Leninist Communist Party.
Organizational forms of educational and methodological guidance
Authors: Banshchikov V. M.
Published: October 2021

The question of how to organize educational and methodological work in Meduniversities, what organizational forms, what cells to create to guide this work is a serious issue that is of no small importance. At the same time, speaking about the organizational forms of management of educational and methodological work, one cannot limit ourselves to indicating these forms only at the local level, in Meduniversities, it is also necessary to indicate the organizational forms of this leadership in the center, in NKZdrav.
Rationalizing hospital nutrition
Authors: Golubovsky I. E. , Funt I. M.
Published: October 2021

The decisive successes in the construction of the USSR, the cultural growth of the masses and the involvement of members of the working family in production, in connection with the complete elimination of unemployment, set before the consumer cooperation the task of gradually switching food supply from individual consumption to public catering, as the first condition for the transition from small, single household to a large, socialized one. "
Tendencies and ways of decrease of feto-infantile losses in Tatarstan Republic
Authors: Nikolskaya L. A. , Abrosimov M. Yu.
Published: October 2021

The integrated index level of feto-infantile losses combining mortinatality and infantile mortality iii Tatarstan Republic increased by 10,9% at the expense of its sharp rise in rural region from 1985 to 1995. Mortality in perinatal period (mortinatality is 39,8% and mortality during the first week of life is 31,4%) takes the leading position in its structure suggesting the necessity of reorganization of perinatal help by introducing a three level system with concentration of pregnants and newborns of high risk groups, skilled staff and high material and technical provision in perinatal centres.
Retention of teeth with access to the nose and maxillary cavity
Authors: Piskun A. I.
Published: October 2021

The retention of teeth in the thickness of the jaws and their growth in an unusual place, the phenomena are not so frequent.
Hyperthyroidism and blood picture. Jachson (I. Med. A. 7. 97, No. 26)
Authors: Kramov N.
Published: October 2021

Jachson (I. Med. A. 7. 97, No. 26) examined 600 cases and came to a trace, conclusions
Bladder diverticulum W. Lower (Surg. Gynec. A. Obst. No. 52.1931)
Authors: Tsimkhes I.
Published: October 2021

W. Lower (Surg. Gynec. A. Obst. No. 52.1931) examines his 152 cases of urinary diverticulum. bladder and in the issue of recognizing this suffering gives great value to cystoscopy and especially radiography of the bladder.
Experience of using intramuscular injections of ichthyol in acute and chronic diseases of the female genital area.
Authors: Osilovsky V. M.
Published: October 2021

The effect of ichthyol, introduced psectually into the human body, has not yet been experimentally studied. In Russian and foreign literature, I have not found an answer to this question. Perhaps ichthyol plays the role of an activator of protoplasm, and perhaps the action of ichthyol fits into the theory of irritation of Beer. Sokolsky, Kenis and others consider the action of ichthyol as protein therapy.
Peculiarities of the specialized sanatorium service to children with locomotor system diseases in Tatarstan Republic and ways of its improvement
Authors: Ziatdinov V. B.
Published: October 2021

The peculiarities of the specialized sanatorium service to children with locomotor system diseases are considered. The significance of the sanatorium treatment as an important stage of improvement of medicosocial rehabilitation of patients with scoliosis is emphasized. The complex permanent treatment of children with hip joint pathology in the specialized sanatorium allows to obtain complete recovery of the femur head practically in all the patients with Pertess disease and correspondingly to prevent the development of early and late complications.
Unity of medicine and science
Authors: Salikhov I. G.
Published: October 2021

The achievements of the department in the field of the science of medicine are the fruit of the efforts of its distinguished individual representatives, renowned medical scientists, as well as of the staff as a whole. The remarkable tradition of delivering commemorative speeches provides an opportunity to reflect on the past and, by analyzing the present, to look to the future.
Extrauterine pregnancy and intrauterine contraception
Authors: Mazitova M. I. , Sadykov B. G. , Gubaidullina S. V. , Shaikhutdinova L. N. , Gainanova N. N.
Published: October 2021

The role of intrauterine contraception as a risk factor of extrauterine pregnancy initiation is studied using the analysis results within 4 years in Tatarstan (19921995). As many as 26,9% of the women of fertile age use intrauterine contraception. Extrauterine pregnancy is found, on the average, in 1390 women. The close direct correlation between the use of intrauterine contraception and the incidence of extrauterine pregnancy is revealed suggesting that intrauterine contraception is a risk factor.
Organization of therapeutic care, rehabilitation, and dispensary care for patients with septic diseases
Authors: Bogus K. M.
Published: October 2021

The organization principles of combined and appropriate treatment, rehabilitation and prophylactic medical examination of patients with pyo-inflammatory diseases in the specialized antisepsis centre are presented. The work will be useful for physicians of polyclinics involved in rehabilitation of patients after surgical sepsis.
Professor Victor Petrovich Veselovsky
Authors: Ivanichev G. A.
Published: October 2021

On February 4, 1997 after a long illness passed away an outstanding scientist of Kazan, honored scientist of the Russian Federation and the Republic of Tatarstan, the head of the department of nervous diseases and vertebro-neurology KGMA, President of the International Association of vertebro-neurologists, President of the Euro-Asian Academy of Medical Sciences, Board member of the Russian Society of Neurologists, Editor-in-chief of the magazines "Vertebro-neurology" and "Bulletin of EA AMS", Director of Vertebro-neurological Center of the Republic of Tatarstan and the Russian Federation, Doctor of Medicine.
Prof. L. Puusepp. Chirurgische Neuropathologie.
Authors: Breitman M. Ya.
Published: October 2021

I Band. Die peripherischen Nerven. P. ѴSH + 662, fig. 330, with separate tables 1932
N. E. Ischiondsку. Neuropsyche und Hirnrinde
Authors: Breitman M. Ya.
Published: October 2021

Dr. H. E. Ishlondski's book is in two large volumes.
The method of alkaline loading and its application in the clinic of internal diseases
Authors: Solntseva M. S.
Published: October 2021

The works of recent years have clearly shown the importance that the alkaline-acid balance has in the physiology and pathology of the animal organism. The desire to maintain this balance at a certain height occurs by coordinating the work of a number of organs: the lungs, secreting C02, the liver, taking part in the production of ammonia, the gastrointestinal tract, secerning acid and alkaline secretions and, finally, the kidneys, giving urine with a high acid content and someone's slit, then with less-take part in the regulation of alkalineacid balance. That is why, naturally, the study of the functions of various organs aimed at regulating and maintaining the alkaline-acid balance attracted the attention of clinicians. Rehn and Gnzburg, then Pannewitz, Popescu, Inotesti. Su11a, and finally Rosenberg and Hellfors, studying fluctuations in the concentration of hydrogen ions in urine after loading with alkalis and acids, sought to gain an idea of kidney function aimed at maintaining the gap.- acids. balance, and at the same time apply this method to the study of the functional state of the kidneys in general. However, it turned out to be insufficient to talk about this condition on the basis of determining the Ph of urine. The Ph fluctuations are not always sufficiently prominent, as the review of the data obtained by the authors shows, because the concentration of hydrogen ions is a value depending on the ratio of acid to alkali (voltage 002 and bicarbonate content). This forced us to put forward another method for determining changes in the functions of tissues and kidneys for the introduction of alkali: Mainzer et al., A. G e f t e r emphasized the importance of the determination of bicarbonates in urine and suggested using the method of their determination by gasometric method (according to van Slyke'y), while giving this definition a much greater value than the study of Ph fluctuations alone.
New method of the application of choledochoenteroanastomosis with protection
Authors: Popov A. N.
Published: October 2021

The new method of the formation of biliodigestive anastomosis without the basic defect of existing methods of the surgical intervention regurgitatior of enteric contents with the following development of ascending cholengitis is proposed. The type of anastomosis proposed is recommended for the approbation in clinical conditions for reconstructive operations of biliary tracts.
Anticoagulant and antiprotease therapy of patients with pulmobronchopleural complications of surgical sepsis
Authors: Bogus K. M.
Published: October 2021

The state of hemostasis in 152 patients with bronchopulmonary complications of surgical sepsis is investigated. The thrombohemorrhagic syndrome is diagnosed wherein anticoagulant therapy with heparin is prescribed. Antienzymic therapy using such protease inhibitors as contrical, hordox and E-aminohexoic acid is performed in 48 patients. The terms of normalization depending on the gravity of the pathologic process comprise from 4 to 9 days.
On the question of jejunum sarcomas
Authors: Smirnov E. V.
Published: October 2021

Intestinal sarcoma is a relatively rare disease. It occurs much less frequently than cancer. According to Mikulich, for example, there were only 5 sarcomas per 100 cases of bowel cancer (except recti). The intestine, in comparison with other organs, is also not often affected by sarcoma. According to Nagel's notes on 247 sl. sarcomas, intestinal sarcomas were observed in 3 cases (1%)- Surgical literature is not rich in works devoted to intestinal sarcomas. Korner and Furbank collected 175 sarcomas of the digestive tract before 1907, of which 65 were localized in the small intestine. Sreese in 1914 was able to take 99 sl. intestinal sarcomas. The Russian literature on the issue of intestinal sarcoma has the works of Bondarev, Favorsky, Peacemakers and Punin. Intestinal sarcoma is more common in men (80% according to Noorden) This disease is mainly observed at a young age, from 20 to 30 years (Peacemakers, Bondarev), 30-40 (Corner, Madelung). However, sarcomas also occur at an older age. Of all parts of the intestine, sarcoma is most often found in the small intestine. So Korner and Furbank mark 65 sarcomas of the small intestine, 20 sarcomas of the blind and 11 other parts of the colon. According to Liebman, out of 50 cases in 15 sl. localization was in the 12-digit, in 18 in the skinny, in 14 in the iliac and the rest in other parts of the digestive tract. According to Staemmler (1924), for 184 cases of sarcoma of the small intestine, localization in the jejunum is indicated in 44 cases.
Magnetic resonance imaging in gynecological practice
Authors: Valiullina A. T. , Tukhvatullina L. M. , Bakhtiozin R. F. , Chuvashaev I. R.
Published: October 2021

Magnetic resonance imaging (MRI) has become one of the leading methods of noninvasive diagnostics in the last 10 years. Interest in this type of examination is due to its great potential possibilities: absence of radiation exposure, high natural tissue contrast, obtaining sections of any orientation, possibility of multiple examination and dynamic control, determining not only the anatomical structure of soft tissues, but also their chemical composition.
Treatment of trachoma with the drug L. chaulmoograe
Authors: Batarchukov R. A. , Kruglov A. N. , Kolenko A. B.
Published: October 2021

The treatment of trachoma is currently based on the use of copper preparations, the healing properties of which were known by the ancient Egyptians during this suffering. Therefore, the keen interest shown by ophthalmologists from different countries in the proposal of our compatriot Dr. Delano to treat trachoma ol. chaul- moograe is quite understandable.
Interregional scientific-practical conference “prevention and treatment of complications in endosurgery.
Problems of the development of endosurgery in Russia "
Authors: Ibatullin I. A.
Published: October 2021

The organizers of this conference were the heads of the Tatarstan Endosurgery Association located in Kazan - Cand. honey. Sciences V.V. Odintsov, A.N. Chugunov, I.V. Fedorov and technical leader A.E. Moroshek. Professors Yu. I. Galinger, A. D. Timoshin, K-V. Lapkin, S. G. Shapovalyants, A. A. Gulyaev, Cand. honey. Sciences A. S. Balykin, A. Ya. Andreev, S. V. Shtyrov, surgeons of Kazan clinics.
Impressions from the VI All-Union Congress of Radiologists and Radiologists in Moscow 2-VII-6-III-31 years
Authors: Gasul R. Y.
Published: October 2021

The VI All-Union Congress of Radiologists and Radiologists, after a long break, gathered a relatively large number of participants, among whom there were a lot of young radiologists who had been "confirmed" over the past 2 years of intensive training in our institutes and departments of radiology. Some of them work in industrial areas and in collaboration with a surgeon, a therapist or a biologist were able to deliver both scientific research and also experiment, with the data of which they shared at the Congress. This concerned mainly the issue of industrial injuries among workers of mining metallurgy, coal industry and other industries and the issue of selection in agriculture by means of lighting.
Hydrostatic action of baths with impaired peripheral circulation
Authors: Greenbarg A.
Published: October 2021

Schulhaf (Z. physik. Then Bd 35, H. 3, 1928) notes that the amount of water pressure in different parts of the body, in addition to purely anatomical reasons, depends on the water column. So, for example, if the patient is in a standing bath of a certain depth, then the greatest pressure falls on the peripheral parts of the body and the least on the upper parts of the body.
On the treatment of croupous pneidonia
Authors: Stepukhovich D.  M.
Published: October 2021

With a typical and generally favorable course of pneumonia, there are many cases that do not require any medical intervention. Most pneumonia goes away with any, one might say, even in spite of any therapy. As the former method of bloodletting, so also now sometimes used medicines can only cause harm, but in no way benefit. Still, patients recover often with this treatment. (Strumple).
Reverse shoulder arthroplasty in cases of glenoid defects using primary-revision metaglene
Authors: Kesyan Gurgen A. , Karapetyan Grigoriy S. , Shuyskiy Artem A. , Urazgil’deev Rashid Z. , Arsen'ev Igor' G. , Kesyan Ovsep G. , Shevnina Margarita M.
Published: October 2021

BACKGROUND: Reverse shoulder arthroplasty is one of the surgical treatment methods of the shoulder joint injuries and diseases accompanied by pronounced changes in the anatomy of the articular structures. Considering the positive aspects of reverse shoulder arthroplasty, the indications for this operation are expanding over time. However, during this operation, errors are possible that lead to early dislocation of the endoprosthesis, compression of the metaglene to the scapula, screw instability and migration of the scapular component. Given the lack of a generally recognized clear algorithm of actions in these complex cases, the problem of reversible shoulder arthroplasty in case of defects in the articular surface of the scapula are relevant.
AIM: To develop and evaluate the effectiveness of the method of compensating for the lack of bone tissue of the scapula in the reverse shoulder arthroplasty
MATERIALS AND METHODS: In the Department of Adult Orthopaedics of the N.N. Priorov National Research Medical Center, reverse shoulder arthroplasty was performed in patients with scapular bone mass deficiency, who needed to fill in both marginal defects for the installation of metaglene with the correct angle of inclination, and the replacement of extensive defects with the necessary level of glenosphere lateralization.
RESULTS: Follow-up of patients who underwent glenoid remodeling using bone autoplasty and subsequent shoulder reverse artroplasty within a period of 6 to 24 months. Remodeling and osseointegration of the grafts were determined, without signs of metaglene instability by the end of the 3rd month after the operation. The complex of rehabilitation measures and the time of recovery of movements in the operated joint did not differ from those of conventional reverse arthroplasty.
CONCLUSION: Given the high efficiency of the proposed algorithm, the method used to compensate for the lack of bone tissue of the scapula in shoulder reverse arthroplasty can be recommended for implementation in a wide clinical practice.
Evaluation of the effectiveness of the use of low-traumatic surgical access in the reverse shoulder arthroplasty
Authors: Kesyan Gurgen A. , Karapetyan Grigoriy S. , Shuyskiy Artem A. , Urazgil'deev Rashid Z. , Arsen'ev Igor' G. , Kesyan Ovsep G. , Shevnina Margarita M.
Published: October 2021

BACKGROUND: The number of reversible shoulder joint endoprostheses installed in the world at the present stage is several times greater than the number of hemiarthroplasty performed. Nevertheless shoulder arthroplasty is considered a traumatic operation and can be accompanied by a number of complications, both from the side of implants and due to the traumatic nature of the surgical technique. During surgical interventions on the shoulder joint with a wide dissection of the skin and subcutaneous tissue, iatrogenic damage to structures such as the axillary nerve, posterior and anterior arteries and veins surrounding the humerus can often be detected, which triggers a whole cascade of pathophysiological and regulatory processes in which Interventions immediately release inflammatory mediators. Therefore, orthopedic traumatologists strive to reduce the risk of intra- and postoperative complications, and it is necessary to improve the surgical technique of surgical interventions towards their less traumatic performance.
AIM: Development and evaluation of the effectiveness of the use of low-traumatic surgical access when performing reverse shoulder arthroplasty.
MATERIALS AND METHODS: In the period 20172020, 169 patients with various diseases, injuries of the shoulder joint and their consequences were operated on in the Department of Adult Orthopedics of the N.N. Priorov National Research Medical Center of the Russian Federation, who underwent reverse shoulder arthroplasty according to generally accepted indications. In the main group (84 patients), surgical treatment was performed using a low-traumatic surgical approach, while the control group (85 patients) underwent standard procedures. Functional, clinical and radiological results of surgical treatment of patients of the main and control groups were evaluated and compared after 3, 6 and 12 months.
RESULTS: In the main group, excellent results (25 points on DASH) were observed in 73 patients, good results (2650 points) in 10 patients. In 1 patient, the results were assessed as satisfactory (5175 points). In the control group of observation, the clinical result was worse (68 excellent, 16 good and 1 satisfactory result).
CONCLUSION: On the basis of the performed study, taking into account the better results in the main group of patients, the technique of low-traumatic surgical access for reverse shoulder arthroplasty can be recommended for wide use in clinical practice.
Bazı Baklagil Ağaç Yapraklarının Alternatif Yem Kaynağı Olarak Besin Madde İçerikleri ve Sindirilebilirliklerinin Belirlenmesi
Authors: BOĞA Mustafa , AVCI Barış Cem , KILIÇ Hatice Nur , CİVANER Ayşe Gül
Published: October 2021

Çalışmada, Niğde-Bor yolunda ve Niğde Ömer Halisdemir (OHU) Üniversitesi kampüs içerisinde bulunan farklı baklagil (Fabaceae) ağaçlarından (Leucaeno leucacephala, Robinia pseudoacacia, Colutea arborescens, Cercis siliquastrum, Wisteria sinensis) toplanan yaprakların besin madde içerikleri vein vitro sindirilebilirliklerinin belirlenmesi amaçlanmıştır. Araştırmada kullanılan yem materyallerinde kuru madde (KM), ham protein (HP), ham yağ (HY), ham selüloz (HS) ve ham kül (HK) analizleri ile asit çözücülerde çözünmeyen lifli madde (ADF), nötr çözücülerde çözünmeyen lifli madde (NDF) ve nitrojensiz öz madde (NÖM) değerleri belirlenmiştir. Örneklerin in vitro gaz ve metan gazı üretim miktarları, metabolik enerji (ME), net enerji laktasyon (NEL) ve in vitro organik madde sindirim derecesi (IVOMSD) değerlerinin saptanması amacıyla mezbahanede yeni kesilen koçlardan elde edilen rumen sıvısı kullanılmıştır. Farklı dönemlerde toplanan yapraklar ve türler arasındaki farklılık HSdışı tüm (KM, HK, HP, NDF, ADF ve ADL) değerler için istatistiki olarak önemli bulunmuştur (P
The state of cognitive function in patients with stable coronary artery disease after coronary artery bypass grafting
Authors: Sokolova N. Yu. , Golukhova E. Z. , Savelyeva E. A. , Popov D. S.
Published: October 2021

Aim      To study the cognitive function (CF) state in patients with chronic ischemic heart disease (IHD) depending on the method of coronary bypass (CB), with extracorporeal circulation (EC) or on beating heart.

Material and methods  Postoperative cognitive dysfunction (POCD) is a frequent complication of CB, and its development may depend on the method of surgery, with EC or on beating heart. This single-center, prospective, nonrandomized study included 196 patients with chronic IHD aged 61.0±5.1 years. Patients were divided into two groups based on the CB method: an EC group (n=11) and a beating heart surgery group (n=85). Mean follow-up period was 26±2.1 mos. The state of CF was evaluated before and after CB (at the hospital stage, at 3, 6, 12, and 24 mos.).

Results The mean duration of CF recovery was 3 mos. only in the group of CB without EC (p<0.05), whereas after CB with EC, CF parameters were similar to those during the hospital stage with somewhat reduced values. In 6 mos. after CB, CF normalized to baseline values in both groups (with and without EC). A possible CF decline in patients with chronic IHD after CB depended on the following factors: age older than 60 years (p<0.05), diabetes mellitus with glycated hemoglobin >7.5 % (p=0.001) and 6.5–7.5 % (p=0.03), smoking (p=0.04), atherosclerotic damage of the internal carotid artery (p<0.05), and a Charlson comorbidity index >5 (p=0.03). The CB surgery either with EC (p=0.04) or on beating heart (p=0.04) was associated with the development of CD.

Conclusion      The results of the study allow identifying patients with chronic IHD and POCD-predisposing factors to recommend them beathing heart CB surgery.
Predictive value of laboratory markers in the development of cardiac events in patients with stable coronary artery disease after elective endovascular revascularization
Authors: Svarovskaya A. V. , Arzhanik M. B. , Ogurkova O. N. , Kuzheleva E. A. , Baev A. E. , Garganeeva A. A.
Published: October 2021

Aim      To reveal a relationship between preprocedural laboratory data and adverse cardiac outcomes (CO) in patients with stable ischemic heart disease (IHD) following elective endovascular revascularization (ER).

Material and methods  This study included 225 patients with IHD admitted for treatment to the Research Institute of Cardiology of the Tomsk National Research Medical Center. The study included patients with documented IHD and hemodynamically significant coronary stenoses requiring elective ER. Patients were divided into groups based on the presence of complications: group 1, 98 patients with adverse CO and group 2, 127 patients without adverse CO. Besides evaluation of complaints, history, and objective status, general clinical and biochemical tests were performed for all patients. Concentration of glycated hemoglobin (НbА1с) was measured by immunoturbidimetry (DiaSys Diagnostic Systems). Serum concentrations of insulin, interleukin-6 (IL-6), endothelin 1 (ET-1), and homocysteine were measured by enzyme immunoassay. Blood lipid profile was determined by enzymatic colorimetry (DiaSys). Content of non-high-density lipoprotein (non-HDL) cholesterol (CS) was calculated as: CS – HDL CS. Insulin resistance (IR) was assessed by the HOMА-IR index. IR was diagnosed at the index of 2.77. Statistical analyses were performed with Statistica 10.0 and Medcalc 19.2.6 software.

Results A one-way regression analysis identified predictors for adverse CO following ER. The most significant predictors were fibrinogen (odds ratio (OR), 1.430; 95 % confidence interval (CI), 1.027–1.990), HbA1c (OR 1.825; 95 % CI, 1.283–2.598), homocysteine (OR, 1.555; 95 % CI, 1.348–1.794), ET-1 (OR, 94.408; 95 % CI, 16.762–531.720), triglycerides (TG)/glucose ratio (OR 1.815; 95 % CI, 1.155–2.853). Based on selected factors, logistic regression models were constructed. However, not all models had a high prognostic power. Only concentrations of ET-1 and homocysteine showed a high prognostic capability in respect of the adverse outcome (88.3 and 85.7 %, respectively).

Conclusion      For patients with IHD, the prognostic capability of ET-1 and homocysteine with respect of the risk for adverse CO following ER was the highest compared to other markers. The results of the study are completely consistent with data of literature and can be successfully used in clinical practice for optimizing the medical care of patients after elective ER.
STRATEGY CREATING POSITIVE WORD OF MOUTH BASED ON RELATIONSHIP QUALITY
Authors: Firdaus Firdaus , Mulyanto Kukuh
Published: October 2021

The development of technology had a great impact on the company in introducing or marketing their products to consumers, marketing has become the world's interest. They market of goods, services, property, people, places, events, information, ideas, and organizations. In order to maintain its position in the eyes of consumers, marketers strive to create an ideas and innovation that can attract the interest of market participants. The purpose of this research is done in order to examine the information of variable quality, assurance and responsiveness to the quality of relationships that affect consumer promotions lazada mouth to mouth in Semarang. This data research using questionnaires with a sample of 148 respondents in the city of Semarang. The sampling technique is to use probability sampling, with one of the methods used is purposive sampling. The data obtained and analyzed by Structural Equation Modeling (SEM) with AMOS application 21. The results of this study are: (1) the quality of information, assurance and responsiveness positive and significant impact on the quality of the relationship. (2) the quality of information, assurance, responsiveness and quality of the relationship positive and significant effect on word of mouth.