bluuebunny/crossref_metadata_2025 huggingface dataset:
Rethinking diffusion of vaccines: giving healthcare a better shot
Authors: Savaget Paulo
Published: March 2021

Vaccination is an area of rapid scientific and technological advance and is among the most successful public health interventions ever. However, for its potential to be met, innovation systems should not only make vaccines available: it is also essential that delivery systems suit social desires and local peculiarities. This work presents 2 cases of failures in diffusing vaccines, as social, cultural and political aspects were not well addressed throughout the campaigns. Lessons taken from these cases suggest that instead of focusing merely on increasing immunity, policies should integrate interdisciplinary bodies of knowledge and promote social engagement through bottom-up processes. These approaches are not only keener on improving acceptability and efficacy in delivering existing technologies, but also to create (and adapt) novelties based on local capabilities.
Capital social y malnutrición en población indígena menor de 5 años de cinco cantones de la provincia de Chimborazo.
Authors: Guamán Yupangui Lino Patricio , Rivadeneira Guerrero María Fernanda , Moncayo Benalcazar Ana Lucía , Cóndor José , Astudillo Fabricio , Buitrón Janett , Tello Betzabé , Torres Ana L. , Paúl Astudillo Neira EDITOR:
Published: March 2021

Introducción: El capital social (CS) incluye varios componentes de la organización social, que podrían mejorar la situación de salud. Existe poca información sobre su asociación con la Desnutrición Crónica (DC).
Metodología: El presente estudio transversal analítico fue realizado en los cantones de Riobamba, Alausí, Guamote, Guano y Colta en el periodo 2018-2019. Con una muestra probabilística mediante encuestas a madres/cuidadores se determinó el CS, determinantes de la salud, y mediciones antropométricas. El análisis de datos se realizó mediante regresión bivariada y multivariada, con cálculo de Odds e intervalos de confianza al 95 %, se consideró significativo un valor de p menor a 0.05, se utilizó el software SPSS versión 25.0.
Resultados: Se estudiaron 1228 niños, el 50.5% (n = 620) hombres y 49.5% (n= 680) mujeres. Con DC el 52.6% (n = 326) de los hombres y el 46.7% (n = 284) de las mujeres. Los hijos cuyos padres no han escuchado hablar sobre desnutrición infantil presentaron un OR 1.46 (IC95%=1.13-1.9) para el desarrollo de DC. Esta asociación se mantuvo significativa después del ajuste por sexo, edad del niño/a, número de hijos e ingresos económicos.
Conclusiones: La asociación entre el CS y la DC en la población indígena menor de 5 años de la provincia de Chimborazo se observó en la falta de información sobre nutrición infantil.
Score PELOD-2, predictor de Mortalidad en Pacientes ingresados en la Unidad de Cuidados Intensivos en el Hospital Baca Ortiz desde Marzo hasta Agosto de 2018.
Authors: Pazmiño Miranda Ana María , Reinoso Recalde David Israel , Donoso León Luis Stalin
Published: March 2021

Introducción: El síndrome de disfunción multiorgánica (SDMO) es la falla de dos o más órganos en pacientes críticamente enfermos, por lo que se han creado puntajes que permiten estimar su mortalidad. El objetivo del presente estudio fue determinar el valor diagnóstico de la escala “Disfunción Pediátrica Logística de órganos-2” (PELOD-2) como predictor de mortalidad en los pacientes ingresados en la Unidad de Cuidados Intensivos (UCIP) en el Hospital Baca Ortiz.
Métodos: Este estudio observacional analítico fue realizado en la UCI del Hospital Pediátrico “Baca Ortiz”, Quito-Ecuador en Marzo a Agosto 2018. Se incluyeron todos los posibles casos analizables. Las variables edad gestacional, sexo, variables clínicas del puntaje PELOD-2 y mortalidad. El Grupo 1 (G1): niños con fallecimiento, Grupo 2 (G2): niños vivos. Se calculó Sensibilidad (S), Especificidad (E), Valor Predictivo Positivo (VPP), Valor Predictivo Negativo (VPN) de cada Puntaje.
Resultados: 188 casos fueron incluidos. Fueron 97 mujeres (51.6%). Pacientes de 1 a 4 años de edad 66/188 (35.1%) Con falla respiratoria 100 casos/188 (53.7%). Mortalidad de 35 casos/188 (18.6% IC 95% 18.21-19.02%). PELOD2 ≥16 mortalidad 63%. OR 511.7 (IC95% 29.4-8909) P<0.0001.   S:62.9%, E:100%, VPP:100%, VPN:92.2%. Exactitud: 93.1%.
Conclusión: El puntaje PELOD-2 es un predictor de mortalidad aceptable, y altamente específico.
Esplenectomía Laparoscópica en el Hospital Pediátrico Baca Ortiz, estudio retrospectivo de los últimos 10 años.
Authors: Arboleda Bustan Jenny Elizabeth , Zambrano Eduardo , Astudillo Paúl
Published: March 2021

Introducción: La esplenectomía es un tratamiento estandarizado en niños con trombocitopenia.  El método de laparoscopía, en este tratamiento, minimiza los procesos post-operatorios y se ha difundido su aplicación en la comunidad científica. El objetivo del presente estudio es realizar una descripción de la casuística y utilidad de la esplenectomía laparoscópica en los niños con patología hematológica.
Métodos: El presente estudio observacional, retrospectivo se realizó en el Hospital Pediátrico Baca Ortiz. Se revisaron expedientes clínicos de los últimos 10 años de pacientes con indicación de esplenectomía quirúrgica. Se analizan variables demográficas, clínicas y de resultados. Se utiliza estadística descriptiva.
Resultados: Ingresaron al estudio 14 pacientes que tuvieron una esplenectomía quirúrgica vía laparoscópica. La mayoría de estos pacientes son del sexo femenino, con patologías hematológicas como esferocitosis y púrpura trombocitopénica idiopática (PTI). En el 50% se realizó colecistectomía además de esplenectomía. El tiempo quirúrgico varió de 60 a 120 minutos.
Conclusiones: La esplenectomía laparoscópica es considerada una técnica compleja dentro de los procedimientos de laparoscopia, pero es ideal para los pacientes con patología hematológica, por lo que es la técnica de elección. Una ventaja de la esplenectomía laparoscópica es el menor tiempo de recuperación y hospitalización, con heridas quirúrgicas más pequeñas.
Variables predictivas de Diámetro y Longitud de Inserción de Tubo Endotraqueal en niños de 1 a 120 meses ingresados en el Área de Terapia Intensiva del Hospital “Vicente Corral Moscoso” en el Período Mayo 2018- Octubre 2019
Authors: Rubio Ramírez Adriana Evelyn , Escalante Canto Paúl , Astudillo Neira EDITOR: Paúl
Published: March 2021

Introducción: La principal causa de morbi-mortalidad pediátrica incluye el compromiso de la vía aérea, por lo que una correcta intubación salva la vida del paciente. El objetivo de este estudio fue determinar las variables predictivas de diámetro y longitud de inserción de tubo endotraqueal en niños intubados en el área de terapia Intensiva del Hospital Vicente Corral Moscoso, Cuenca-Ecuador.

Métodos: En el presente estudio observacional con una muestra no probabilística tipo censo, se determinó el diámetro del tubo endotraqueal (DTE) utilizado y la profundidad de inserción mediante rayos x para determinar la Longitud del Tubo Endotraqueal (LTE). Se utiliza correlación y regresión lineal para predecir DTE y LTE en base a Edad, Peso y Talla de niños de 1 a 120 meses de edad. Se utiliza estadística no paramétrica.

Resultados: Fueron 102 casos que constituyeron una frecuencia de intubación del 30.6 %, el motivo más frecuente fue patología respiratoria. La ecuación de predicción del DTE=3.54+0.14*(edad años) + 0.04*(Peso kg). R2=0.65, P=0.0001, para LTE=10.36+0.31*(edad años) + 0.18*(Peso kg). R2=0.65, P=0.0001.

Conclusiones: El diámetro y longitud del tubo endotraqueal se correlacionan con variables propias de cada paciente como edad y peso.
Asociación entre el retraso en la Búsqueda de Atención Médica y el Nivel de Gravedad, en niños con fiebre que acuden al Servicio de Emergencias
Authors: Mayorga Chávez Gabriela Carolina , Santillán Vásconez Ana María , Arnao Noboa Adriana , Pereira Olmos Hugo , Astudillo Neira EDITOR: Paúl
Published: March 2021

Introducción: El retraso en búsqueda de atención médica (RBAM) definido como un tiempo mayor a 48 horas antes de consultar un profesional podría influir en la severidad de las enfermedades en los niños.

Métodos: En el presente estudio de cohorte prospectivo, se realizaron entrevistas estructuradas a tutores de niños que acudieron con fiebre a la emergencia del Hospital Baca Ortiz, verificando su estado de salud 5 días después, mediante una llamada telefónica. Las variables incluyeron demográficas, tiempo de atención y gravedad del cuadro. Se utilizó Chi cuadrado y Riesgo Relativo (RR) para buscar la relación entre dichas variables.

Resultados: Fueron 304 pacientes ingresados al estudio, 41.1 % presentaron RBAM, cuyas principales causas fueron la administración de medicación sin receta médica en 48 % y la falta de detección de signos de alarma en 26.4 %. Los pacientes con RBAM presentaron más riesgo de requerir hospitalización (RR 1.88 IC 95 % 1.53-2.13 ), cuidados intensivos (RR 2.86 IC 95 % 1.00 – 8.17), presentar una infección bacteriana severa (RR 2.36 IC 95% 1.81 – 3.07), síndrome de respuesta inflamatoria sistémica (RR 2.47 IC 95 % 1.80 – 3.38), hospitalización al quinto día posterior a su valoración (RR 2.63 IC 95 % 1.94 – 3.57) y de mantenerse hospitalizado por más de 5 días (RR 1.46 IC 95 % 1.15 – 1.85).

Conclusiones: El RBAM influye significativamente en la gravedad de los niños con fiebre, siendo la administración de medicación sin prescripción médica su principal causa.
Factores asociados a Síndrome de Dificultad Respiratoria del Recién Nacido del Hospital José Carrasco Arteaga. Estudio de casos y controles
Authors: Palacios Sacoto Johana Alicia , Ochoa Brito Tania Marcela , Astudillo Neira EDITOR: Paúl
Published: March 2021

Introducción: El Síndrome de Dificultad Respiratoria (SDR), es la causa más frecuente de morbilidad y mortalidad en el recién nacido. Se debe conocer la patología y sus factores asociados a la misma para un manejo oportuno y eficaz. El objetivo del presente estudio fue determinar los factores asociados al Síndrome de Dificultad Respiratoria de los recién nacidos en el Hospital “José Carrasco Arteaga” en el año 2018.

Métodos: Estudio de casos y controles con una relación de 1:2; se parearon respecto al sexo y al mes de nacimiento. Se comparó en relación al peso, edad materna, Apgar, controles prenatales, edad gestacional, tipo de parto, patología materna, presencia de líquido meconial y el uso antenatal de corticoides. Se evaluó la asociación mediante OR (IC 95%) y la significancia con la prueba X2; considerando una significancia estadística a una P<0.05.

Resultados: Se estudiaron 188 casos y 376 controles. El SDR tuvo asociación positiva con el peso bajo y macrosomía (OR 8.15 IC 0.91-73.46 P<0.001); prematurez y posmadurez (OR 2.05 IC 1.29-3.27 P<0.001); nacimiento por cesárea (OR 2.74 IC 1.88-4.01 P<0.001); presencia de líquido meconial (OR 5.30 IC 2.75- 10.22 P<0.001); hipertensión gestacional (OR 2.25 IC 1.23 -4.10 P=0.01); anemia gestacional (OR 2.06 IC 1.30 -3.27 P<0.001).  El uso de corticoides antenatales fue protector (OR 0.33 IC 0.17 – 0.62 P<0.001).

Conclusiones: Los mayores factores asociados a SDR fueron el bajo peso y macrosomía conjuntamente con la presencia de líquido meconial.
Sistem Pengembangan Karir Sekretaris Desa Setelah Pengangkatan Menjadi ASN
Authors: Amri Amri , Kurniawan Rudi
Published: March 2021

This study aims to explore information on the career development system of the village secretary after being appointed as a civil servant (ASN). The location of the study was conducted at the North Aceh Civil Service and Human Resources Development Agency (BKPSDM) involving 10 informants who were determined based on purposive sampling. The results of the study found that there are still 322 active village secretaries who did not get career development as civil servants. From this research, it can be assumed that the village secretary career development system in North Aceh Regency has not been implemented completely. There are still barriers, including lack of awareness, low education, motivation, desire and aspirations to progress and develop, as well as low enthusiasm and enthusiasm of the village secretary. Besides, there is also a lack of attention from the stakeholder and never allowing taking part in training. Meanwhile, some efforts should be provided to support the career of the village secretary such as providing a coaching, direct superior directives, work motivation from the leadership and providing opportunities for training.
Una Pedagogía del Nosotros
Authors: Martínez-Domínguez Luis Manuel
Published: March 2021

Modelo pedagógico que propone la educación en conciencia, como auténtica, creativa y plena apertura de sí en el Nosotros para autorrealizarse de forma apoteósica. Cuando no se da este desarrollo nosicéntrico, desde donde se habita con felicidad, los sujetos se encierran en egocentrismo o alocentrismo inmaduro que es causa y motivo de violencia. La Pedagogía del Nosotros, desde la fenomenología y el refuerzo de la neurociencia y otras disciplinas, describe desde la Sociedad, la Familia y la Educación, lo que civilizaciones de todos los tiempos y lugares, han procurado desarrollar desde sus diferentes cosmovisiones: el Ágape de la Grecia Clásica, el Ren del confucionismo, la Caritas del cristianismo, el Ubuntu africano, El Iithar (إيثار) del Islam, la Fraternité de la Ilustración…, y tantas otras comunidades humanas que la han inculturado, es decir, que la han vivido desde su cultura, a su manera. Aquí se presenta en lo esencial, como columna vertebral de lo admisible por todos, para educar con un fundamento compartido.
Evaluación educativa centrada en el nosotros
Authors: Martínez-Domínguez Luis Manuel
Published: March 2021

El propósito de este libro es describir un modelo de evaluación educativa basada en el “nosotros”, a la que llamo evaluación habitativa. La evaluación habitativa es una evaluación educativa y educadora a la vez. Esta forma de evaluar puede utilizarse en todo tipo de programas de intervención socioeducativa y psicopedagógica. Ya sea centrada en el ámbito familiar, en los programas ocupacionales y de promoción laboral, en las actuaciones educativas de todo tipo y para todas las edades, en las acciones de animación sociocultural… El objetivo de la evaluación habitativa es la de promover la autorrealización nosicéntrica del “yo” dentro de un “nosotros-maduro” de tal forma, que cada persona despliega su originalidad aceptando al presente que le es dado y dándose como presente para, entre todos y al mismo tiempo, configurar el “nosotros” con madurez y funcionalidad. La evaluación habitativa no pretende ofrecer “las soluciones”, sino “evidencias fenomenológicas” para que cada sujeto en su comunidad valore, decida y se proponga sus vías de solución global, dejando abierta las posibilidades estratégicas y educativas, que podrán ser muy variadas, y que convendrá que se ajusten a las posibilidades y limitaciones del “yo” y del “nosotros” en cada momento.
Announcement of Retraction
Authors: Lee Simon
Published: March 2021

The editorial board announced that this article has been retracted on March 30, 2021. If you have any further question, please contact us at: bmr@sciedupress.com
BRB system stability considering frame out-of-plane loading and deformation zone
Authors: MacRae Gregory , Lee Chin-Long , Vazquez-Colunga Saul , Cui Jian , Alizadeh Saeid , Jia Liang-Jiu
Published: March 2021

A simple and economical design approach is described for a BRB system, consisting of a BRB within a steel frame, subject to in-plane and out-of-plane seismic displacements. The approach avoids out-of-plane system or brace instability while allowing large frame out-of-plane deformations and desirable BRB axial performance. It also limits the compressive/tension force ratio. It is based on the simple concept that a brace will be stable with two moment-releases (hinges) but that an out-of-plane buckling mechanism may occur with more than two. The hinges are detailed as specified deformation zones (SDZs) at the brace ends. The hinges use a plate which can yield about its weak axis during out-of-plane movement. Simple methods to assess the stability of the brace itself (between hinges) are developed, an example is provided illustrating how the monotonic deformation demand of the simple plate hinge can be assessed, and detailing recommendations are made to restrict the deformation of the boundary elements at the brace ends.
Efficacy of Antimicrobial Lock Solutionsagainst Catheter-Related Infections in Hemodialysis Patients
Authors: Skoulatou Maria , Alikari Victoria , Toulia Georgia , Kavga Anna , Govina Ourania , Siopi Dimitra , Zormba Irene , Skoulatou Christina , Gerogianni Georgia
Published: March 2021

INTRODUCTION: Hemodialysis patientsare at increased risk of catheter-related bloodstream infections (CRBSI) and catheter thrombosis asdialysis requires regular access to blood circulation through catheters. Antimicrobial Locking Solutions (ALS) containing anticoagulants and antimicrobial agents (antibiotic/non-antibiotic) are used to seal catheters in order to prevent thrombosis and CRBSI.

PURPOSE: The investigation of internationalclinical studies regarding the efficacy and safety of the various ALS treatments for CRBSI in hemodialysis patients (HD patients) comparing to conventional approaches such as heparin treatment or catheter removal.

METHODOLOGY: The review included prospective or retrospective clinical studies, randomized clinical trials or cohort studies published since 2015. Publications were retrieved from the “Pubmed”, “Google Scholar” and “Elsevier” databases using ‘catheter’, ‘catheter removal’, ‘hemodialysis’ ‘bacteremia’, ‘antimicrobial lock therapy’as key words.

RESULTS: 17 articles were found to meet the criteria for this systematic review. These studies investigated locking solutions containing various antibiotic (Cefazolin, Gentamicin, Vancomycin, Cotrimoxazole, Daptomycin, Trimethoprim) or/and non-antibiotic agents (Citrate, taurolidine, ethanol, urokinase, Cathasept) +/- anticoagulants, single or in various combinations. The main objective of these studies was to identify the efficacy of ALS with respect to CRBSI risk rates, catheter exchange rates and related adverse effects.

CONCLUSIONS: Antimicrobial Locking Therapy appears significantly beneficial forHD patients as it reduces CRBSI risk and prolongs catheter survival at considerable rates, so it should be seriously considered for systematic useagainst catheter-related infections. Further researchis required to establish safe and effective prevention and therapeutic protocols as alternatives to catheter removal practices.
Association between Health and Wealth among Kenyan Adults with Hypertension
Authors: Hanna Daniel R. , Campbell Jennifer A. , Walker Rebekah J. , Dawson Aprill Z. , Egede Leonard E.
Published: March 2021

BACKGROUND: This paper examines the relationship between hypertension and wealth in a national sample of Kenyan adults.

METHODS: Data from 27,552 individuals from the Demographic and Health Survey Program (DHS) for Kenya were analyzed. Wealth index, a cumulative measure of household standard of living, was the outcome. The final analysis was stratified by gender with covariates added in blocks (demographics, economic, and cultural) to investigate the independent association of hypertension with wealth index.

RESULTS: Approximately 7.6% of those with hypertension had a wealth index above the median. For women and men, hypertension was significantly associated with higher wealth index (women ß=0.26; CI=0.19; 0.34; men ß=0.36; CI=0.19; 0.53). After adjusting for age, rural location, children, employment, education, ethnicity, and religion, hypertension maintained statistical significance with wealth index for both women and men (women ß=0.06; CI=0.01; 0.11; men ß=0.20; CI=0.08; 0.31).

CONCLUSIONS: As Kenya as a nation undergoes health care reform while also experiencing a high burden of hypertension, the results presented here provide preliminary evidence that may be used in support for decision makers for the wealth effects of health interventions. Additional work is needed to understand the longitudinal relationship between hypertension and wealth at the national level. 
Therapeutic Challeng es of COVID-19 in a Patient Admitted to the Psychosomatic Ward: A Case Report
Authors: Salehian Razieh , Nasr Esfahani Mehdi
Published: March 2021

Introduction: Early diagnosis of 2019-nCoV infection is of great importance and can be challenging in psychiatric patients, especially when a mental illness such as somatoform disorder causes one or more bodily symptoms because the clinical features of this group of patients may be more confusing compared with non-psychiatric patients. On the other hand, treating this infection in psychiatric patients faces some challenges. Case Presentation: A case of the 2019-nCoV infection is reported in a patient who was admitted to the psychosomatic ward with a diagnosis of somatic symptom disorder. The patient had a history of numerous unexplained physical complaints, usually complained of some new physical symptoms when informed of the time of his discharge. Although the possibility of misdiagnosis was high, based on examinations and some paraclinical evaluations, the patient underwent a simultaneous diagnosis of COVID-19. Unlike usual, he did not complain of any new physical complaints after informing of the 2019-nCoV infection and was willing to be discharged. Some diagnostic and therapeutic challenges regarding 2019-nCoV infection in the patient were examined. Conclusions: There are three clinically relevant learning points to be noted from this case report. Firstly, the importance of paying attention to the patient's complaints in any mental patient, even disorders related to unexplained physical complaints. Secondly, the introduction highlights the differences in the care of patients with COVID-19 between psychiatric and non-psychiatric patients and the need for a multidisciplinary approach. Third, this introduction identifies a crucial diagnostic role for CT thorax in symptomatic patients with suspected COVID-19 because the false-negative rate with RT-PCR COVID-19 nasopharyngeal swabs is high.
Blade Runner 2049
Authors: Botz-Bornstein Thorsten ,   Society for the Philosophic Study of the Contemporary Visual Arts
Published: March 2021

What is the “miracle” that protein farmer Sapper Morton mentions when he says to K: “You never saw a miracle”? It is the transformation of inorganic life into organic life. Rachael, who was a replicant in the old Blade Runner (though falsely believing she is human) gave birth to twins. Tyrell had “perfected procreation,” in the words of Niander Wallace, but his knowledge has been lost. The theme of 2049 revolves around the scientific and philosophical question whether machines can become organic. Is a human only an accumulation of parts or cells, or does the quality of being human denote more than the sum of its parts? Is a bioengineered human a real human or simply a sophisticated machine? Furthermore, the film associates the organic with the real. Real humans as well as real memories are linked to a larger whole. The article reflects these constellations against various philosophical stances.
Tax exemptions for value added tax in the Republic of Serbia with a comparative analysis of tax exemptions in the EU
Authors: Nikšić Jasmina
Published: March 2021

The modern era of capitalism is characterized by mass production. Consumer society is the target of producers whose demand depends on financial success of companies. An important correlation between consumers and producers is created by advertising and propaganda activities. Traditional and new media through which the advertising message is conveyed play an important mediating role. Marketing agencies nowadays offer advertising creation services, run by an entire team of PR managers. Many commercials are created in a way that approaches the form of art, without taking any care about ethical principles. In this paper, we highlight the manipulative, persuasive influence of advertising and the abuse of children in advertisements.The first part of the paper covers the definition of advertising and the chapter about advertising in the media. In the second part of paper, attention is paid to the impact of advertising on consumers, as well as on the role of children abuse in commercials. Based on the analyzed commercials, it is concluded that children in advertisements are used as a means of achieving economic goals, and that the elements of the analyzed advertisements are used to manipulate children.
Mesenchymal stem cells and COVID-19
Authors: Vujić Dragana , Simić Marija
Published: March 2021

With the appearance of the first cases of COVID-19 infection, which had a severe clinical picture accompanied by respiratory insufficiency, as well as multiorgan dysfunction, mesenchymal stem cells became the subject of intensive research. The main cause of tissue and organ damage in patients with COVID-19 infection is thought to be a cytokine storm, which is the result of an imbalance in the regulation of the host immune system. Previous studies have shown that mesenchymal stem cells have an immunomodulatory effect and can prevent and reduce the cytokine storm triggered by the SARS-Cov-2 virus. Numerous clinical studies on the use of mesenchymal stem cells in patients with a severe clinical picture of COVID-19 are underway. Undoubtedly, cell therapy could be of great importance in the treatment of patients with a severe clinical picture of COVID-19, but it takes time to consider the efficacy and safety of such therapy, which is possible only through controlled multicenter clinical studies.
Endocrine disrupting chemicals vs longevity in the COVID-19 era: Public health implications
Authors: Polychronopoulos Evangelos , Balias George , Skouroliakou Maria , Kapartziani Chrysa , Kalofiri Paraskevi , Rallis Michail
Published: March 2021

Endocrine disrupting chemicals (EDCs) are a controversial topic within scientific, regulatory, socio-economic, and public health circles. Nonetheless, every community's physical environment is currently under siege from various EDCs, many of which are still unknown. EDCs affect the normal function of the endocrine, neurological, and immune systems, consequently diminishing successful development, reproductive adulthood, and decreasing survival. Beyond any doubt, adverse effects of EDCs are a consequence of multiple everyday exposures to hundreds of chemicals in unknown environmental doses such as pesticides, insecticides, polycyclic aromatic hydrocarbons, dioxins, polychlorinated biphenyls, dichlorodiphenyltrichloroethane, brominated flame retardants, and parabens. Considering that thousands of other known endocrine disruptors fly under the radar of scientific and medical communities due to existing methodological pitfalls, the situation is quite precarious. In 2012, the World Health Organization published a report emphasizing that EDCs are a major and emerging global public health threat. The combined power of informed consumers, industry innovations, and government regulations is the driving force in this fight. Therefore, research advancements, public health infrastructure, and environmental protection agencies are the fundamental pillars in combating the ever-growing issue of EDCs.
A world view, subject and narration or: In the West, Nothing New
Authors: Vukašinović Želimir
Published: March 2021

In the age of terrorism and virulence, an absence of a true community remains an essential experience of an undeniable subject who, finally justified by its (self) isolation, tends to rediscover the concreteness of existence and vitality of the world of life. This experience will lead us to a possible reading of the narrative structure of identity as a horizon for an understanding of the history of metamorphoses of the subject. This interpretation of the function of narration illuminates a relation between the subject and its story which redefines our contemporary, pragmatically reduced, perception of practice.
Physiotherapy in contemporary higher vocational education
Authors: Jovanović Stevan , Stojanović-Jovanović Biljana
Published: March 2021

In the last fifty years there has been a dramatic development and changes in all segments of the biomedical sciences which contributed to the development of expertise in the field of physiotherapy. While the aim of the first higher education cycle is training for basic skills required for independent practice, second education cycle should provide training in planning processes, projects, decision making, development of leadership skills, with the assessment process, as well as special physiotherapy knowledge and skills in selected areas and technologies. The formation and organization of joint master study programs related to the physiotherapy can be very interesting organizational model. This can be achieved by a greater degree of flexibility and adaptability of programs that stimulates the horizontal mobility of students within the European higher education area. The development of the physiotherapy profession was marked by a significant increase in the volume of knowledge and skills, so the World Confederation for Physical Therapy and its European region, developed a strategy according to which are necessary all three cycles of higher education.
God, religion and death in the essays and novels of Ernesto Sabato
Authors: Čanović Ana
Published: March 2021

The paper is entirely dedicated to the way of looking at concepts of God, religion and death in essays and novels of Argentine writer Ernesto Sabato. The intention is to present the manner in which the relationship with God can be defined both in the Sabato's biography and in his essays and novels. In the introduction are stated the basic biographical data with a focus on two events that marked the last decades of Sabato's life. In the paper are also discussed the issues of Sabato's consideration of God, religion and death and the possibility of Sabato's declaring in a religious sense. In the central part, the research of the Sabato's relationship towards mentioned concepts was carried out on examples of collection of the essays "One and the Universe ", the essays "Before the End" and "The Resistance", and novels "The Tunnel" and "on Heroes and Tombs ". It is concluded that Sabato's relationship with God changed in different periods of life and from work to work, depending on life circumstances in which he lived and worked.
Research on buyers' attitudes towards the use of solar panels in households in the Republic of Serbia
Authors: Nikolić-Ristić Dragana , Đokić Nenad
Published: March 2021

In modern living conditions, the concept of sustainable development is one of the current research topics. In this context, the focus on greater use of renewable energy sources is supported both in the member states of the European Union and in the Republic of Serbia. The research problem of this paper refers to the attitudes of customers towards the use of renewable energy sources. The subject of the research is about the attitudes of customers towards the use of solar panels and panels in households. The first part of the paper sets out the theoretical basis of the research through a review of previous empirical studies that dealt with the same research problem, while the other sections are dedicated to explaining the research methodology, presenting and discussing the results of research on consumer attitudes towards the use of solar panels in households. The significance of this empirical study lies in the fact that it explores customer attitudes with regard to their sociodemographic characteristics.
The research on female motivation for entrepreneurship in the Republic of Serbia
Authors: Popović Blaženka , Paunović Tamara , Maletić Radojka
Published: March 2021

Modern social development trends, as well as globalization and internationalization, require significant changes in entrepreneurship, with a tendency of increasing involvement of women in business. The main focus of the paper is to determine the significance of different motives that influence women in the Republic of Serbia for entrepreneurship, depending on their age, education, marital status, length of entrepreneurial experience and number of employees. Empirical research was conducted on a sample of 162 female entrepreneurs in the territory of the Republic of Serbia. The data were analyzed using factor analysis, Mann-Whitney U and Kruskal-Wallis test. The research results indicate that the motivation for entrepreneurship can be grouped into two areas. Non-parametric tests have found that there are differences in the significance of different motivations for women entrepreneurs of different age, education level, marital status, length of service and number of employees. The results of the research confirm that women entrepreneurs differ in terms of motives for entrepreneurship.
Financial support as a determinant of small and medium-sized enterprises economic growth
Authors: Volf Dejan , Vapa-Tankosić Jelena , Ignjatijević Svetlana
Published: March 2021

European Union integration and revitalization of economy after the global economic crisis require small and medium-sized enterprises in Republic of Serbia to face more complex and dynamic environment which requires greater competitiveness in terms of improved quality, efficiency and management practices. However, the competitiveness of the regional SMEs is still at a much lower level compared to other European SMEs. Pointing out to the characteristics of small and medium enterprises, a logical conclusion can be drawn that state support for this sector is important. When forming the support modalities, the sector should not be viewed as a uniform whole. This paper analyses the importance of financial and non financial support for SMEs in terms of organizational capability and competiveness. Roy's test, Pearson's coefficient of contingency (ch), and multiple correlation coefficients (R) are applied as univariate statistical procedures. MANOVA and discriminant analysis show a difference and clearly defined boundary between other forms of support and financial forms of support in all the analyzed units. The findings also indicate that the financial forms of SME support influence the SMEs organization capability and competitiveness, given that in most cases the benefits of state institutions are viewed through forms of financial support.
Foreign trade in agricultural products between the Republic of Serbia and the Republic of Kazakhstan: A decade since the signing of the Free trade Agreement
Authors: Simić Milica , Stankov Biljana
Published: March 2021

Modern international economic relations, among other things, are characterized by establishing bilateral and multilateral cooperation between countries in order to liberalize trade relations. The implementation of reached free trade agreements affects economic trends in the signatory countries, the intensification of their foreign trade as wll as the increase in the attractiveness of countries as investment destinations. From 2000 onwards, Serbia has signed several free trade agreements with European countries and the United States. Ten years ago, a free trade agreement was signed with the Republic of Kazakhstan in order to encourage the development of mutual trade and economic relations, accelerate economic development, improve living and working conditions, increase employment and establish fair competition between economic entities from Serbia and Kazakhstan. The subject of the mentioned trade relations are also agri-food products, whose production in Serbia is supported by an excellent raw material base, and has always been a part of national tradition and culture. The research subject of this paper is foreign trade of agricultural products between Serbia and Kazakhstan with regard to free trade agrrements. The research aim is to determine the differences in the movement of exports and imports between the mentioned countries in the period before and after the signing of the free trade agreement.
The significance of determination of the absolute value of gravity in geodesy
Authors: Naod Sofija
Published: March 2021

The gravity is used to solve geodesy's primary tasks, such as determining geoid and defining the height and gravimetric reference networks of different scales, from national to global. Knowledge of gravity is of great importance for both metrology and geodetic metrology. In addition to the historical overview of absolute gravimeters, this paper presents the theoretical basis of the most commonly used method for determining the absolute value of gravity. The principle of operation of the absolute gravimeter FG5 and the importance of international comparison of absolute gravimeters are briefly presented. An overview of the gravimetric reference systems is given, emphasizing the establishment of the International Reference Gravimetric System. The previous works concerning the absolute determination of acceleration due to Earth's gravity field in Serbia are presented. Finally, the importance of determining the absolute value of gravity from the geodetic and metrological perspective is pointed out. Both national and international significance of determining absolute gravity in defining gravimetric reference systems and the importance of absolute gravity in monitoring global phenomena are emphasized.
The role of company management in the choice of organizational structure
Authors: Mihajlović Milan , Milenković Nikola , Andžić Slobodan
Published: March 2021

The dynamic and turbulent market environment poses great demands and challenges to the company's management. Adequate management response to these challenges should ensure more efficient, effective and economical business operations, significantly higher quality financial statements, as well as a modern organization of the company. The subject of this paper is the modern internal organization of the company. Based on that, it will be considered what is the impact of the internal organization on the overall business of the company, and what mechanisms and methods management can and should apply in this area, all based on relevant legal and professional regulations.
Relationship between time perspectives, socioedograpsic variables and life satisfaction
Authors: Slavković Ana
Published: March 2021

The problem of this research is to examine the relationship between dominant time perspectives, sociodemographic variables and life satisfaction.The aim of this research is to examine the possibility of successfully predicting life satisfaction by six dimensions of time orientation (positive past, negative past, hedonistic present, fatalistic present, positive future, negative future), gender, age and socioeconomic status. The sample included 136 respondents aged 18 to 60 years. The dimensions of the time perspective were operationalised by short version of Zimbardo's 18-item questionnaire. The construct of life satisfaction is operationalised by a scale whose authors are Diener et al. (1985). The assumed model, which includes six dimensions of time perspective, gender, age, and socioeconomic status, can explain 36% of the variance in life satisfaction. According to the results of the research, socioeconomic status, negative orientation towards the past, gender, fatalistic orientation towards the present and negative orientation towards future significantly contribute to the explanation of the variance of life satisfaction. Negative aspects of time orientation are (according to the research results) better predictors of life satisfaction than positive ones, because they include a depressive position, enslavement to failures and frustration, endless recycling of a bad past, feeling like a passive actor unable to change anything, belief that games are pre-set and that only negative outcomes are possible, which leads to strengthening of maladaptive patterns of thought and behavior, lack of will, withdrawal from life struggles. The outcome is a failure and dissatisfaction with life, which intensifies depressive rumors and leads to an even more negative view of oneself, one's own experience and possible chances in the future.
Attitudes of Spanish language teachers at university level towards film as a didactic resource
Authors: Pajić Sonja
Published: March 2021

In Spanish language didactics in the world is present the the application of film as a didactic resource. In the paper is analyzed the application of film as a didactic resource in teaching Spanish. The purpose of research is to see the actual state of film application at public and private universities in Serbia, as well as attitudes of teachers towards film as a didactic resource. The research was conducted with the help of questionnaire which questioned the attitude of teachers towards the film application in Spanish language teaching. Obtained results point out at the fact that film is not used enough in Serbia, as well that do not exist its systematical application, that there is no difference between public and private educational system although teachers have positive attitude towards film application in Spanish language teaching. On the basis of the research it can be concluded that there is ground for systematical implementation of film in teaching process. Also, guidelines are suggested in order to develop support to film application in order to promote Spanish language teaching process in Serbia.
The phenomenon of fear in the collection 'Princ Vatre' from Filip David and 'Sara i Serafina' from Dževad Karahasan
Authors: Beširović Nejira
Published: March 2021

In literary works, fear appears as a phenomenon frequently because fear is something that humans face from the beginning of their lives. This paper strives to examine the source, characterization, the outcome of this phenomenon in the works "Princ Vatre" and "Sara I Serafina", notice similarities of the nature of fear between the works, and to provide a look at their reflexes and outcomes. This phenomenon is important from a psychological aspect and a philosophical one, so this paper will even study those points of view so that it can be seen how this phenomenon is being transposed between literary works. The paper shows these works as post-modern achievements that thematize and contextualize different events, but mostly deals with the origin and the effects of fear.
Molecular docking analysis of stachydrine and sakuranetin with IL-6 and TNF-α in the context of inflammation
Authors:   Department of Anatomy, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai - 600 077, Tamil Nadu, India, Prathap Lavanya
Published: March 2021

Inflammatory is cascade process triggered by pro-inflammatory cytokines and anti-inflammatory. In the present study anti-inflammatory activity of Stachydrine and Sakuranetin were studied against the inflammatory target proteins IL-6 and TNF-α by using molecular docking analysis. Both compounds showed the good binding with selected target proteins. Compared to Sakuranetin, the Stachydrine have lowest binding energy and good hydrogen bond interactions. Hence results of study indicated that Stachydrine possessed high and specific inhibitory activity on tumor necrosis factor-α and interleukin-6.
Las especies de Arctodictis mercerat, 1891 (Metatheria, Borhyaenidae), grandes carnívoros del Mioceno de América del Sur
Authors: Forasiepi Analia , Goin Francisco J. , Tauber Adan A.
Published: March 2021

Durante la mayor parte del Cenozoico, los grandes vertebrados carnívoros de América del Sur estuvieron repre-sentados por aves fororacoideas, cocodrilos, serpientes gigantes y mamíferos metaterios como los Borhyaenidae. Entre estos últimos, Arctodictis munizi Mercerat, 1891 representa al boriénido de mayor tamaño hasta ahora conocido. Un nuevo espécimen de A. munizi recolectado en la Formación Santa Cruz (Mioceno Medio) en Cañadón Las Totoras (Provincia de Santa Cruz, Argentina), nos ha permitido describir su anatomía craneal, discutir las relaciones filogenéticas del género Arctodictis y revisar la situación taxonómica de varios especímenes problemáticos. Un estudio de los sedimentos relacionados sugiere condiciones ambientales caracterizadas por una estacionalidad fuerte, ambientes abiertos, frecuentes arroyos pequeños y pastizales. A partir del análisis morfológico y filogenético hemos concluido que: (1) Arctodictis es un grupo natural soportado por los siguien-tes caracteres derivados: dentarios fusionados o fuertemente anquilosados en la sínfisis; P/p 1 orientado transversalmente, m1-3 con un lóbulo labial de la corona sobre la raíz posterior, foramen infraorbitario ubicado sobre el M1, palatinos expandidos detrás del último molar y raíces de los premolares de forma globosa. (2) El género incluye por lo menos dos especies: A. munizi y A. sinclairi. El espécimen UCMP 39250 referido por Marshall a cf. Arctodictis sp. podría representar un gran esparasodonte próximo a los protilacíninos. (3) Existe una amplia variabilidad en tamaño y robustez entre diferentes individuos.
Os carcharhiniformes (cCondrichthyes, Neoselachii) da Bacia de Alvalade (Portugal)
Authors: Antunes Miguel Telles , Balbino Ausenda Cáceres
Published: March 2021

The uppermost Miocene, Esbarrondadoiro Formation (Alvalade basin, Portugal) yielded more than 10 thousandSelachian teeth at Santa Margarida, Esbarrondadoiro and Vale de Zebro outcrops. Forty-five taxa were identifiedbelonging to the orders Hexanchiformes, Squaliformes, Lamniformes, Carcharhiniformes, Torpediniformes and Myliobatiformes. The Carcharhiniformes make up about 40% of the selachian fauna that has been identified in the studiedarea. The different distribution of the Carcharhiniformes (as well as that of the other orders) by the three sitespoints out to distinct environments in the corresponding areas: Esbarrondadoiro indicates relatively deeper, ratherstill waters; Santa Margarida represents a very littoral area and rough waters; while Vale de Zebro was a (probablyinner) part of a gulf with muddy bottoms. At the Alvalade Basin localities there are several “temperate” elements that still are present in Portuguese waters. However the high frequence of Carcharhinus, a genus that is scarce at present off Portugal, indicates waters somewhatwarmer than today’s but less warm than during Tortonian times. This is corroborated by the large number of Dasyatisspecies and the rarity of Raja. We may conclude that moderately warm (less warm than during Tortonian, but warmerthan today’s) waters predominated in the Alvalade Basin close by the end of Miocene. The scarcity of pelagic forms and especially of the larger pelagic predators points out to a quite narrow gulf and not to an open Atlantic front. The faunal differences between the Tortonian near Lisbon and the Messinian of the Alvalade Basin also indicate a rather confined gulf.
Tityosteus, a marine fish (Arthrodira, Homostiidae) from the Emsian of Aragón, Spain, and its distribution
Authors: Mark-Kurik Elga , Carls Peter
Published: March 2021

A right marginal plate (over 11 cm long) of Tityosteus cf. rieversae Gross, 1960, emend., has been found in the late part of the Early Emsian (late Zlichovian) in the Mariposas Fm. of the Eastern Iberian Cordillera in southern Aragón. The palaeoecological conditions correspond to a hemipelagic ensialic basin, with predominant elements of Hercynic biofacies but still with photic bottom. The Emsian genus Tityosteus is now known from the Hunsrück Schiefer of Germany and the closely connected Ibero-Armorican Trough and also from the more distant Minusinsk Basin of southern Siberia. Palaeo-oceans between western Europe and southern Siberia were no zoogeographical barriers for these large, possibly microphagous fishes in open sea. The name of the type species of Tityosteus is emended.
Alethopteris lancifolia Wagner, a rare element of the lower Westphalian “Fern Ledges” of Atlantic Canada
Authors: Wagner Robert H
Published: March 2021

Description of a plant impression from the lower Westphalian (Langsettian) “Fern Ledges” at Saint John, New Brunswick, and identification with Alethopteris lancifolia Wagner, a European species of the same general age. Comparison is made with similar species.