bluuebunny/crossref_metadata_2025 huggingface dataset:
Le sculpteur Francesco Bordoni, collaborateur des Francini
Authors: Cicali Giulia
Published: March 2021

Der florentinische Bildhauer Francesco Bordini, der um 1601 im Gefolge seines Meisters Pierre de Franqueville nach Paris kam, war einer der wichtigsten Mitarbeiter Tommaso Francinis im Bereich des Schmuckbrunnenbaus in Frankreich. Der vorliegende Artikel behandelt die Ausbildung der zwei Männer in Florenz und ihre Kenntnis der großen toskanischen Gartenanlagen des ausgehenden 16. Jahrhunderts, in denen Skulpturen und Brunnen wesentliche Bedeutung zukam. Dann werden die ersten Schritte des Bildhauers am Hof Heinrichs IV. beleuchtet : schon bald arbeitete Bordoni mit Francini zusammen und scheint, außer den Vasen und Wasserkannen des großen Gartens von Fontainebleau, eine Anzahl Bronzefiguren für Brunnen und Grotten von Saint-Germain entworfen zu haben. Er scheint auch der Schöpfer von fünf Bronzemasken zu sein, die in Fontainebleau aufbewahrt werden (Brunnen im Cour du Cheval blanc und im Cour des Offices). Vor 1617 soll Bordini schließlich zusammen mit Francini für Léonora Galigaï an den Brunnen des Schlosses von Lésigny-en-Brie gearbeitet haben.
L’aménagement hydraulique des jardins bas de la villa de Gondi à Saint-Cloud (1628-1636)
Authors: Decrossas Michaël
Published: March 2021

L’article présente les nouveaux aménagements hydrauliques qui furent ordonnés à Saint-Cloud, à partir de 1627 environ, par Jean-François de Gondi. Profitant de la forte déclivité du terrain dans la partie basse vers la Seine, le nouveau propriétaire a voulu doter le «jardin bas » d’un important complexe de fontaines dont la construction semble avoir été achevée en 1636. L’allée du Mail fut totalement réaménagée et agrémentée de bassins, au centre et sur les abords où prirent appui, du côté de la pente, la Cascade et le Grand jet. À l’extrémité de l’allée fut construite la fontaine du bout du Mail dont le nom du concepteur, «Francini » , est connu par un acte de 1628. La complexité du programme hydraulique et la conception des différentes pièces d’eau nous invitent à attribuer l’ensemble de ces travaux à l’un des Francini, Tommaso ou Alessandro. Un nom d’architecte apparaît toutefois dans une expertise en 1636. Raturé, il semble difficile à lire, mais il pourrait s’agir de l’architecte Augustin Ier Guillain.
Association of Baseline Urinary Metabolic Biomarkers with ADPKD Severity in TAME-PKD Clinical Trial Participants
Authors: Hallows Kenneth R. , Althouse Andrew D. , Li Hui , Saitta Biagio , Abebe Kaleab Z. , Bae Kyongtae T. , Miskulin Dana C. , Perrone Ronald D. , Seliger Stephen L. , Watnick Terry J.
Published: March 2021

Key Points

Urine excretion of two key glycolytic enzymes correlated with autosomal dominant polycystic kidney disease (ADPKD) severity (height-adjusted total kidney volume and eGFR) at baseline in the TAME-PKD study population.

These findings are the first to provide evidence in human urine samples that upregulated glycolytic flux is a feature of ADPKD severity.

Future analyses will test whether metformin affects ADPKD disease progression and urinary metabolic biomarkers in patients during the study.

Background

Recent work suggests that dysregulated cellular metabolism may play a key role in the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD). The TAME-PKD clinical trial is testing the safety, tolerability, and efficacy of metformin, a regulator of cell metabolism, in patients with ADPKD. This study investigates the cross-sectional association of urinary metabolic biomarkers with ADPKD severity among TAME-PKD trial participants at baseline.

Methods

Concentrations of total protein, targeted metabolites (lactate, pyruvate, succinate, and cAMP), and key glycolytic enzymes (pyruvate kinase M2 [PKM2], lactate dehydrogenase A [LDHA], and pyruvate dehydrogenase kinase 1 [PDK1]) were measured by ELISA, enzymatic assays, and immunoblotting in baseline urine specimens of 95 TAME-PKD participants. These analytes, normalized by urinary creatinine or osmolality to estimate excretion, were correlated with patients’ baseline height-adjusted total kidney volumes (htTKVs) by MRI and eGFR. Additional analyses were performed, adjusting for participants’ age and sex, using multivariable linear regression.

Results

Greater htTKV correlated with lower eGFR (r=−0.39; P=0.0001). Urinary protein excretion modestly correlated with eGFR (negatively) and htTKV (positively). Urinary cAMP normalized to creatinine positively correlated with eGFR. Among glycolytic enzymes, PKM2 and LDHA excretion positively correlated with htTKV, whereas PKM2 excretion negatively correlated with eGFR. These associations remained significant after adjustments for age and sex. Moreover, in adjusted models, succinate excretion was positively associated with eGFR, and protein excretion was more strongly associated with both eGFR and htTKV in patients <43 years old.

Conclusions

Proteinuria correlated with ADPKD severity, and urinary excretion of PKM2 and LDHA correlated with ADPKD severity at baseline in the TAME-PKD study population. These findings are the first to provide evidence in human urine samples that upregulated glycolytic flux is a feature of ADPKD severity. Future analysis may reveal if metformin treatment affects both disease progression and the various urinary metabolic biomarkers in patients throughout the study.
Diagnostic Walkabouts: Seventeen Years of Specialized Training for Horticultural Professionals
Authors: Malinich Timothy , Kowalski Jacqueline , Behnke Charles
Published: March 2021

A diagnostic walkabout (DW) is an in-field diagnostic training program for professionals in the green industry (greenhouse, landscape, nursery, and turf businesses). DWs have been scheduled annually since 2002 and are easily replicable, fee-based programs that provide cost recovery. DWs also serve as a mentoring program for new Extension educators. Four generations of Extension Educators have participated. Recently, the annual program has been sponsored by state and regional trade associations. What began as an educational outreach program has become a bridge spanning Extension, trade associations, businesses, and generations of Extension educators.
Money Minute: Using Short Informational Videos to Address Financial Hardships Caused by the COVID-19 Pandemic
Authors: Sneed Christopher , Berry Ann , Barnes Shelly , Calhoun Donna , Hagan Tracy , Hethmon Marci , Jones Karen , Metzger Barbara
Published: March 2021

The COVID-19 pandemic has created a money crunch for some families. To help families struggling financially while capitalizing on clients’ newfound at-home time, University of Tennessee Extension consumer economics leadership team developed a series of money management videos called Money Minute. The primary purpose of the videos is to provide research-based financial education during this time of financial hardships. Filmed using Zoom, each video offers a piece of research-based information, a listing of additional resources, and a call to action. The video series has proved to be effective in reaching clientele with financial information in the midst of a pandemic, and the methods can be replicated or adapted by others.
Analisis Makna Simbol Batu Tallu dan Täbä Tallu Tentang Pemeliharaan Allah di Salutambun dengan Menggunakan Teori Ernst Cassirer
Authors: Jeffri Andri Saputra
Published: March 2021

Batu and Täbä are symbols and cultural relics in Salutambun. The main ideas represented through Batu and Täbä were the providence of God in the history of the local people. Reviving this meaning is the main purpose of the author. The last few decades after the community was dominated by Christianity, the center of community attention switched to the background of symbol founders (non-Christians) and the emergence of the title of "Guardian of the village" indicating idolatry. Both of these problems bore rejection of the symbol, and the meaning represented in it began to be forgotten by society. By that, the author was encouraged to construct the meaning of symbols as well as show their relevance to Christianity. The methods used are qualitative research methods, with symbolic interaction strategies. The source of information is customary parents, some community leaders, and churches, as well as documents/records history of Salutambun. The collected data was analyzed using the symbol theory of Ernst Cassirer. After conducting research, it was discovered that Batu and Täbä represented God's providence and contributed to the preaching of the gospel.Batu dan Täbä adalah simbol sekaligus peninggalan budaya di Salutambun. Gagasan utama yang direpresentasikan melalui Batu dan Täbä adalah pemeliharaan Allah dalam sejarah masyarakat setempat. Menghidupkan kembali makna inilah yang menjadi tujuan utama penulis. Beberapa dekade terakhir setelah masyarakat didominasi oleh Kekristenan, pusat perhatian masyarakat beralih ke latar belakang pendiri simbol (non-kristen) dan munculnya gelar “penjaga kampung” yang mengindikasikan penyembahan berhala. Kedua masalah ini melahirkan penolakan terhadap simbol, dan makna yang direpresentasikan di dalamnya mulai dilupakan masyarakat. Olehnya itu, penulis terdorong untuk mengonstruksi makna simbol sekaligus menunjukkan relevansinya bagi kekristenan. Metode yang digunakan adalah metode penelitian kualitatif, dengan strategi interaksi simbolik. Sumber informasi adalah orang tua adat, beberapa tokoh masyarakat dan gereja, serta dokumen/catatan sejarah Salutambun. Data yang terkumpul dianalisis menggunakan teori simbol dari Ernst Cassirer. Setelah melakukan penelitian, ditemukan bahwa Batu dan Täbä merepresentasikan pemeliharaan Allah dan memiliki kontribusi bagi pemberitaan Injil.
Impact of the COVID-19 Crisis on Learning, Teaching and Facilitation of Practical Activities in Science upon reopening of Irish Schools
Authors: Chadwick Ruth , McLoughlin Eilish
Published: March 2021

IIn September 2020, Irish schools reopened following their emergency closure due to the COVID-19 crisis. Measures were put in place to minimise the risk of transmission of the virus within schools and communities. However, these measures were likely to impact on teachers’ capacity to facilitate learning in science, particularly the practical and investigative aspects of the Irish curriculum. This research explores the impact of the measures in place to limit virus transmission on teaching and learning in science, particularly on practical activities. The period of focus is the three months (September to November 2020) following the school closures. The research aims to highlight the implications of the COVID-19 crisis on science teaching and learning in Irish schools. The research will also provide recommendations to lessen the impact on primary and second-level science education to improve student learning and engagement in science.
BOAS PRÁTICAS ASSITENCIAIS DIRECIONADAS À GESTANTE EM TEMPOS DE COVID-19
Authors: Isabelly Medeiros de Góes Anny , Ferreira de Araújo Renata , Kelyany Duarte Costa Karén , Sátiro Xavier de França Inácia
Published: March 2021

Objetivo: Identificar as evidências cientificas sobre os cuidados à gestante no contexto da pandemia do COVID-19. Método: Revisão integrativa da literatura realizada no mês de fevereiro de 2021, nas bases de dados Cumulative Index to Nursing and Allied Health Literature (CINAHL), Scientific Electronic Library Online (SciELO), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Medical Literature Analysis and Retrieval System Online (MEDLINE) e SCOPUS por meio dos descritores “Coronavirus”, “Pregnant Women” e “Nursing Care”. Foram utilizados como critérios de inclusão artigos completos, em português, inglês e espanhol com publicações no último ano. Resultados: Oito estudos compuseram a amostra final, dos quais desvelou-se duas categorias analíticas: (1)- Cuidados de Enfermagem direcionados as gestantes com covid-19 e (2)- Características clínicas importantes para tomadas de decisões do cuidado às gestantes com covid-19. Conclusão: Evidencia-se a transcendência do papel da enfermagem na prática assistencial, educativa e gerencial para colaborar na adesão e realização às boas práticas recomendadas em âmbito nacional e internacional, considerando-se a realidade local e a necessidade de atualização constante na temática.

Palavras chave: Coronavírus. Gestantes. Enfermagem. Cuidados de Enfermagem.
VIVÊNCIA DOS TRABALHADORES RURAIS FRENTE AO USO DE AGROQUÍMICOS: UMA REVISÃO INTEGRATIVA
Authors: Aires Cavalcante Leite Laura , Ferreira de Araújo Renata , Isabelly Medeiros de Góes Anny , Kelyany Duarte Costa Karén , Maciel Ferreira da Silva Francilene
Published: March 2021

RESUMO: O Brasil é um dos maiores consumidores mundiais dos agroquímicos. Devido a esse fato, encontra-se susceptível a maiores índices de intoxicação. Estes, por sua vez, caracterizam-se por um conjunto de efeitos nocivos, desencadeando o desequilíbrio do organismo dos trabalhadores, por meio de um ou mais agentes tóxicos. Desse modo, o objetivo centra-se nas dificuldades enfrentadas pelos trabalhadores rurais, frente ao uso dos agroquímicos. Para isso, foi feito uma revisão integrativa, realizada por intermédio da Biblioteca Virtual em Saúde (BVS). A revisão considerou a compilação de artigos mais recentes, entre 2016 e 2020, centrados na temática dos agroquímicos e dos trabalhadores que fazem uso deles. Como resultado, foram selecionados seis artigos, que mostraram sobretudo a predominância de trabalhadores rurais que fazem uso de agentes tóxicos como sendo sexo masculino, com idades entre 30 e 60 anos, renda menor ou igual a dois salários-mínimos. Dentre as principais dificuldades enfrentadas estão o uso de EPI, consequências na saúde física e emocional, despreparo com relação ao uso dos agroquímicos e falta de receita agronômica. Desta feita, observa-se que os trabalhadores rurais representam um grupo que necessita de cuidado e monitoramento, para avaliar e amenizar as consequências do uso de agroquímicos no cotidiano dos mesmos.

Palavras chave: Agroquímicos. Saúde da População Rural. Trabalhadores Rurais.
CARACTERIZAÇÃO METODOLÓGICA DAS PESQUISAS SOBRE O ESTRESSE OCUPACIONAL E A SÍNDROME DE BURNOUT: UMA REVISÃO SISTEMÁTICA DE LITERATURA
Authors: Américo Dantas Camilo de Souza Renato , Bento Cavalcanti Jonathan , Luiz Silva Camêlo Edwirde
Published: March 2021

RESUMO: Este estudo buscou revisar sistematicamente a literatura acadêmica a fim de responder a seguinte questão norteadora: "Quais os parâmetros metodológicos adotados em pesquisas sobre o Estresse Ocupacional e a Síndrome de Burnout nos últimos 2 anos de produção científica internacional?". Incluíram-se artigos publicados entre janeiro de 2019 e janeiro de 2021 nas plataformas SciELO e LILACS/BVS. Dos 3314 trabalhos inicialmente encontrados, 150 foram selecionados após a aplicação das etapas de filtragem, sendo as maiores prevalências observadas: artigos de 2019 (77/66,7%), de autores brasileiros (100/66,7%), da área de Enfermagem (61/40,7%), com desenho Transversal (111/74%) e Quantitativo (138/92%). Nesse sentido, reitera-se a importância de se conhecer as principais características e delineamentos do referencial bibliográfico do Estresse Ocupacional e da Síndrome de Burnout a fim de que se possa garantir a continuidade de pesquisas futuras sobre o tema. Palavras chave: Burnout. Estresse ocupacional. Revisão de literatura. Saúde mental.
COVID-19 E ERITEMA NODOSO: UM RELATO DE CASO
Authors: Mansur Geórgia , Oliveira Castro de Azevedo Oliveira Bernardo , Lívia Silva Moura Amanda , Lucas Tadeu Carvalho Castro Tiago , Lemos Araújo Diogo , Henrique Machado Guilherme
Published: March 2021

RESUMO: A pandemia pelo SARS-Cov-2 presente no último ano possui muitas manifestações clínicas desde quadros influenza-like leves até síndrome respiratória aguda grave (SRAG). Algumas manifestações dermatológicas também se fazem presentes no quadro clínico. OBJETIVO: Realizar relato de caso de uma das manifestações dermatológicas da infecção pelo Covid-19, o Eritema Nodoso (EN). MÉTODO: Trata-se de um relato de caso, descritivo, baseado na clínica de uma paciente com manifestações iniciais de síndrome gripal, sendo confirmado via RT-PCR infecção pelo SARS-Cov-2, evoluindo com quadro de EN. Os dados do relato foram obtidos pelo prontuário e exames laboratoriais. RESULTADO: As manifestações cutâneas apresentadas por pacientes portadores de infecções virais, como o Covid-19, são variadas e apresentam relação com tais patógenos. Estão relacionados à fisiopatologia fenômenos como reação de hipersensibilidade tipo IV, hipercoagulabilidade sanguínea e acometimento sistêmico culminando em exacerbada resposta inflamatória e produção de citocinas. Tal resposta orgânica pode levar a manifestações cutâneas, como o EN, o qual pode ser causado por outras etiologias descartadas durante a investigação do caso clínico relatado. CONCLUSÃO: Este artigo ao abordar outras manifestações da COVID-19, pode ser um meio de auxílio em futuros diagnósticos desta doença. O EN, neste caso, foi após o diagnóstico de uma infecção viral, mas, nada impede, que em pacientes assintomáticos seja uma forma inicial de chegar a essa hipótese. Dessa forma, o relato tem como finalidade ampliar meios diagnósticos e expor a relação da corona vírus com demais manifestações clínicas. Palavras chave: Pandemia. Infecções por coronavírus. Betacoronavírus. Eritema nodoso. Manifestações cutâneas.
ANÁLISE DE PREVALÊNCIA DE RETINOPATIA DIABÉTICA EM PACIENTES ATENDIDOS NO HOSPITAL DE OLHOS DO TOCANTINS NO ANO DE 2020
Authors: Cunha Costa Eduardo , Helene Nunes Cazarotto Walter , Carlos Diniz Arraes João , Lima Arruda Rejanne
Published: March 2021

OBJETIVO: Analisar a prevalência de retinopatia diabética nos pacientes atendidos no Hospital de Olhos do Tocantins, localizado na cidade de Araguaína, no ano de 2020. MÉTODOS: Estudo epidemiológico realizado por meio da análise de prontuários de pacientes atendidos no Hospital de Olhos do Tocantins, da cidade de Araguaína, no ano de 2020. As variáveis analisadas foram: idade, sexo, uso de insulina, tempo de tratamento da diabetes, tipo de retinopatia diabética, hipertensão arterial e presença de catarata. Os dados foram coletados mediante acesso ao Sistema de Gestão Hospitalar Gemmius® implantado e utilizado no hospital em estudo, e em seguida realizou-se a tabulação dos dados através do aplicativo Microsoft Excel. RESULTADOS: Foram selecionados 236 prontuários de pacientes atendidos no ano 2020 com este diagnóstico. Após a análise observou-se que 48,73% dos pacientes tinham idade entre 41 a 60 anos, 47,46% tinham mais que 60 anos e 3,81% de 0 a 40 anos. Em relação ao sexo 55,08% eram indivíduos do sexo masculino e 44,92% do sexo feminino. Quanto ao uso de insulina, 41,95% faziam uso e 58,05% não usavam. Dentre os pacientes avaliados, 65,25% apresentavam diagnóstico de hipertensão arterial e 68,22% diagnóstico de catarata. Em se tratando do tempo de tratamento de diabetes 48,56% faziam tratamento entre 6 e 15 anos, já em relação ao tipo de retinopatia diabética, a proliferativa mostrou-se mais relevante sendo 39,83% delas. CONCLUSÃO: Dos pacientes que faziam uso de insulina, 48,98% apresentavam retinopatia diabética proliferativa, e 43,83% tratavam a mais de 15 anos de diabetes mellitus.

Palavras chave: Estudo oftalmológico. Diabetes mellitus. Saúde pública.
ABORDAGEM FISIOTERAPÊUTICA AO IDOSO NA ATENÇÃO PRIMÁRIA À SAÚDE: UMA REVISÃO INTEGRATIVA
Authors: Mayara Agustinho da Silva Jerssica , Rayane Bezerra Lemos Thainá
Published: March 2021

OBJETIVO: Identificar a abordagem fisioterapeuta do idoso na Atenção Primária à saúde. MÉTODOS: O presente estudo trata-se de uma pesquisa integrativa da literatura. A coleta de dados se deu pela Biblioteca virtual em saúde, no período de dezembro a fevereiro de 2021 com os seguintes descritores “Fisioterapia” AND “Idoso” AND “Fisioterapia” AND “Atenção Primária à Saúde” RESULTADOS: Foram encontrados 54 artigos científicos do ano de 2015 a 2021 com texto completo disponível e após os critérios de exclusão e inclusão 05 artigos foram analisados. Os profissionais precisam estar atentos para receber e orientar os pacientes, nesse sentido, o Núcleo Ampliado de Saúde da Família e Atenção Básica faz parte do primeiro contato, onde o Fisioterapeuta atua com estratégias de prevenção e reabilitação para os idosos, o que evidencia sua importância na reabilitação junto com a equipe da Atenção primaria traz inúmeros benefícios para esses usuarios. CONCLUSÃO: Diante deste contexto, o fisioterapeuta é capacitado para realizar uma reabilitação resolutiva de acordo com cada individualidade do paciente idoso na atenção primaria, este faz a diferença, pois conta com a equipe multiprofissional para dar um proposito frutífero para as questões de saúde trazidas pelos usuários.

Palavras chave: Reabilitação. Idoso. Atenção primária à saúde.
Thermal stability and polymorphic transformation kinetics in β-MnTe films deposited via radiofrequency magnetron sputtering
Authors: Mori Shunsuke , Hatayama Shogo , Ando Daisuke , Sutou Yuji
Published: March 2021

A manganese telluride (MnTe) compound is an interesting polymorphic semiconductor with physical properties differing greatly among various polymorphs. In this study, the thermal stability and polymorphic transformation kinetics in β-MnTe films obtained via radiofrequency magnetron sputtering were investigated. The obtained MnTe films with a composition range of 50.5–46.1 at.% Te exhibited a single β phase. The polymorphic transformation temperature from the β (wurtzite-type) to an α (NiAs-type) phase decreased with increasing the Te content. In the non-isothermal analysis using differential scanning calorimetry, the activation energy for β → α transformation was measured to be 1.41 eV, based on Kissinger plots. The retention time of β-MnTe was also investigated via the Ozawa method, and it was estimated to be retained for 4.5 × 109 years at 25 °C. The estimated Avrami exponent of 3.5 indicated that two- and three-dimensional growth at a constant nucleation rate was dominant at the intermediate stage of β → α transformation.
Public Participation and the Governance of Mineral Resources in Zimbabwe
Authors: Chikova Rangarirai , Chilunjika Alouis
Published: March 2021

Public participation in policy issues by the locals is a crucial ingredient that guarantees the success of any policy decision, national project and public programme.  Public participation should permeate every sphere of governance. In this vein, Zimbabwe is endowed with numerous mineral resources. The indigenous Zimbabwean are statutorily deemed as the owners of the mineral resources hence their participation in policy processes and spaces that relate to the governance of natural resources is pertinent. However, it was noted that the Zimbabwean population is not fully benefiting from the extraction of these mineral resources. The paper therefore explores the magnitude and essence of public participation in the governance of mineral resources in Zimbabwe. In achieving this, the paper is informed by Arnstein’s ladder of participation as the theoretical framework. In addition, data was gathered from documentary review and in-depth interviews with key informants. The study observed that public participation in respect of mineral governance can be undertaken through public hearing meetings, national budget consultative meetings and alternative mining indabas. However, the current level of participation is within the range of non-participation and lower tokenism. In addition, there is also lack of feedback and information flows in one direction from the Government officials to the citizens. The Government does not really take seriously the contributions from the public. The study therefore proffered some recommendations to enhance the levels of knowledge and participation by the public in the governance of mineral resources in Zimbabwe.
EVALUATION OF BACTERIAL ISOLATES DETECTED IN NASOPHARYNX AND
MIDDLE EAR OF CHILDREN WITH OTITIS MEDIA WITH EFFUSION.
Authors: Lakshmanan Somu , Zaffrullah Nufra Senopher , Manimaran Vinoth
Published: March 2021

To analyze the bacterial prole of middle ear uid in children with otitis media with effusion and to correlate the bacterial isolates from the middle
ear uid and nasopharynx in children with otitis media with effusion. This is a prospective observational study conducted in the Department of
ENT, Head and Neck surgery from October 2018 to October 2020. 60 patients who fullled the inclusion and exclusion criteria were taken up for
the study. During General anesthesia, nasopharyngeal culture samples were collected and the middle ear uid samples were collected at the time of
myringotomy were sent for bacteriological culture analysis using standard culture techniques. The results were obtained using paired sample t test
and chi square test, analysis was done using SPSS software version 22. Bacteria were cultured in 12 (20%) out of 60 samples of middle ear uid and
the pathogens isolated were 5 (41.6 %) of Staphylococcus aureus, 2 (16.7 %) of each had Pseudomonas aeruginosa, Staphylococcus epidermidis
and Hemophilus inuenza and 1 (8.3 %) had Streptococcus pneumoniae respectively. On comparing the outcomes of nasopharyngeal c/s with
respect to middle ear uid c/s, it was not statistically signicant (p Value > 0.05). In the present study, the middle ear uid in children with otitis
media with effusion are sterile and the bacterial isolates from the nasopharynx bears no correlation with that of the middle ear uid
CLONIDINE AS AN ADJUVANT TO HYPERBARIC BUPIVACAINE FOR SPINAL
ANESTHESIA IN ELDERLY PATIENTS UNDERGOING INFRAUMBLICAL
SURGERIES
Authors: Singhal Purushottam , Pandey Suresh , Chittora . S. P.
Published: March 2021

Background: Use of adjuvant with small doses of local anesthetics is a preferred technique for spinal anesthesia for lower limb surgeries. This
study tested the hypothesis that addition of small doses of clonidine augments the spinal block levels produced by hyperbaric bupivacaine in
patients without affecting the side-effects.
Materials and Methods: This was a prospective, randomized, double-blind study. Above 60 years patients were allocated to three equal groups.
Group C received 10 mg hyperbaric bupivacaine without clonidine while Group C and Group C received 15 μg and 30 μg clonidine with 15 30
hyperbaric bupivacaine respectively for spinal anesthesia. Effect of clonidine on sensory block levels was the primary study outcome measure.
Motor blockade and hemodynamic parameters were also studied.
Results:Asignicantly higher median block levels were achieved in Group C (P < 0.05) and Group C (P <0.05) than Group C. Highest median 15 30
sensory block level, the mean times for sensory regression to T12 level and motor block regression were statistically signicant between Groups C15
and C and between Groups C and C. On comparison of fall in systolic blood pressure trends, there was no signicant difference in the clonidine 30
groups as compared with the control group.
Conclusions: In elderly patients, clonidine when used intrathecally in doses of 15 μg or 30 μg with bupivacaine, signicantly potentiated the
sensory block levels and duration of analgesia without affecting the trend of systolic blood pressure as compared to bupivacaine alone. Clonidine in
doses of 30 μg however facilitated the ascent of sensory level block to unexpectedly higher dermatomes for a longer time.
A SURVEY TO ASSESS KNOWLEDGE, ATTITUDE AND PRACTICES TOWARDS
COVID-19 AMONGST NHS HEALTHCARE WORKERS AT A TERTIARY HEALTH
BOARD IN THE UNITED KINGDOM
Authors: Roy Poorwa , Davuluri Praveen , Roy Nandini
Published: March 2021

Background and aim: The world is currently facing a public health emergency in the form of COVID-19 pandemic. United Kingdom conrmed
it's initial cases in February 2020 and since then the NHS (National Health Services) and its healthcare workers have been working diligently to
ght this pandemic facing unprecedented challenges.
Materials and methods: A cross-sectional knowledge, attitude and practices (KAP) survey was conducted using a questionnaire among
healthcare professionals belonging to an NHS University Health Board in Wales, UK. The responses were assessed and relevant statistical analyses
were performed using SPSS software.
Results: Atotal of 208 frontline NHS Workers participated in the study. Mean knowledge score in the study was 87.83%. Majority (67.79%) of the
participants had a high knowledge score. Knowledge scores were found to have a positive association with age. The general attitude among the
participants was found to be optimistic with a mean attitude score of 69.87%. Practices varied amongst the participants with 77.5% reporting
regular use of the mask at work.
Conclusion: This study reects that majority of healthcare professionals had a sound knowledge and understanding about the pandemic with an
optimistic attitude towards its control. Majority of them have been implementing safe practices at workplace.
CURB BEFORE IT BLOOMS: REVISING THE ROLE OF PERIODONTIST
Authors: Jain Rachna , Jain Rohit , Khanna Dinkar
Published: March 2021

Periodontitis is a common dental disease affecting a vast majority of population presenting as major challenge to national economy. Traditionally
its prevention is based on enforcing Oral hygiene measures. This short communication suggests various modern approaches along with the
traditional methods in the prevention of periodontitis.
Tiresias: A low-cost networked UWB radar system for in-home monitoring of dementia patients
Authors: Bannon Alan , Rapeaux Adrien , Constandinou Timothy
Published: March 2021

This paper describes Tiresias, a low-cost, unobtrusive networked radar system designed to monitor vulnerable patients in domestic environments and provide high quality behavioural and health data. Dementia is a disease that affects millions worldwide and progressively degrades an individual's ability to care for themselves. Eventually most people living with dementia will need to reside in assisted living facilities as they become unable to care for themselves. Understanding the effects dementia has on ability to self-care and extending the length of time people living with dementia can remain living independently are key goals of dementia research and care. The networked radar system proposed in this paper is designed to provide high quality behavioural and health data from domestic environments. This is achieved using multiple radar sensors networked together with their data outputs integrated and processed to produce high confidence measures of position and movement. It is hoped the data produced by this system will both provide insights into how dementia progresses, and also help monitor vulnerable individuals in their own homes, allowing them to remain independent longer than would otherwise be possible.
3D-Modulation and PI State-Feedback Control for Voltage Source Inverters with Split DC-Link
Authors: Hackl Christoph , Krüner Simon , Song Zhao
Published: March 2021

In this work, a novel three-phase grid inverter topology with split DC-link and LC-filter is discussed. A proportionalintegral (PI) state-feedback current and voltage controller is
designed based on linear quadratic regulator (LQR) theory. The
midpoint current ripple is suppressed by introducing the filter
capacitor voltage as control target. Moreover, a 3-dimensional
Space Vector Modulation (3D-SVM) for this topology is implemented, which allows for larger voltage amplitudes compared
to conventional Pulse Width Modulation (PWM). Realistic simulation results show that the combination of PI state-feedback
controller and 3D-SVM achieves faster and more accurate closedloop dynamics with less oscillations and better decoupling under
varying and unbalanced grid conditions.
The Role of Afghan National and Defense Security Forces in the Security of Afghanistan
Authors: Dr. Muhammad Tariq  , Muhammad Amir  , Saira Bano
Published: March 2021

Security has been one of the greatest concerns of Afghanistan for a long but this aspect gained great momentum in 1979 upon the Russian intervention in Afghanistan. It became a common phenomenon in the entire world in September 2001 when the Pentagon was hard hit by the terrorist attacks. This led to the establishment of a democratic government in Afghanistan Vis Vis the need for an increased security system. With the transition of the NATO forces from Afghanistan in 2014, the Afghan National and Defense Security Forces were assigned the task of maintaining security in the country. Main objectives of the study circle around challenges before the ANDSF, its achievements, and the future of the ANDSF. This paper focuses on the current status of the ANDSF in the security paradigm of the country since security is still a big challenge before the government.
ЗАСТОСУВАННЯ ДІАГРАМИ ІСІКАВИ ПРИ ПРОВЕДЕННІ ТОВАРОЗНАВЧОЇ ОЦІНКИ ЯЄЦЬ ПЕРЕПЕЛИНИХ
Authors: PAMBUK S. , MANOLI T. , SHENGELAYA M.
Published: March 2021

Мета. Метою статті було дослідження стану та перспектив виробництва перепелиних яєць, обґрунтування доцільності застосування інструментів управління якістю, а саме причинно-наслідкової діаграми Ісікави, для виявлення факторів, що впливають на якість яєць перепелиних, встановлення характеру впливу та вагомість цих факторів в рамках проведення товарознавчої оцінки.
Методика. При дослідженні використовували такі методики як: збір інформації, її аналітичне опрацювання та теоретичне узагальнення. Також було застосовано статистичні методи контролю якості (інструменти контролю якості), а саме причинно-наслідкову діаграму Ісікави (Cause and Effect Diagram).
Результати. Узагальнено особливості розвитку виробництва перепелиних яєць, висвітлено тенденції, шляхи підвищення ефективності галузі з метою забезпечення населення високоякісними продуктами харчування, утримання і підвищення конкурентних позицій та створення умов для виходу на зовнішній ринок. За допомогою діаграми Ісікави було встановлено причинно-наслідкові зв’язки причин невідповідного стану шкаралупу перепелиних яєць, визначені головні та вторинні причини виникнення цих невідповідностей. Встановлено, на яких етапах технологічної схеми виробництва вони виникають. Серед основних (первинних) причин визначено такі як: зовнішні умови, умови і якість годівлі, вид та стан птахів, а також людський фактор.
Наукова новизна. Проведено аналіз факторів, що формують якість яєць перепелиних, встановлено причинно-наслідкові зв’язки утворення невідповідностей яєць перепелиних вимогам нормативних документів за допомогою діаграми Ісікави.
Практична значимість. Отримані результати дають змогу виробникам ефективно управляти формуванням та збереженням якості яєць перепелиних з урахуванням особливостей виробництва, технічних можливостей конкретних підприємств, організації товаропостачання та реалізації.
АКТИВНЕ ТА РОЗУМНЕ ПАКОВАННЯ ХАРЧОВИХ ПРОДУКТІВ
Authors: RECHUN O. , PEREDRIY O.
Published: March 2021

Мета. Метою статті є розгляд основних видів активного та розумного паковання харчових продуктів, аналіз їх переваг і недоліків, зокрема, їх випливу на якість і безпечність продуктів та інформативність упаковки, огляд ключових технологій, які можуть бути використані в активних і розумних системах, а також аналіз існуючого законодавства, що регулює використання активного та розумного паковання, та визначення основних перешкод на шляху поширення використання інноваційних видів паковання в Україні.
Методика. Використано методи теоретичного пошуку, системного підходу та логічного узагальнення.
Результати. У статті подано класифікацію активного і розумного паковання, а також коротко розглянуто основні технології, що використовують у розумних і активних системах. Наведено приклади активного та розумного паковання для різних видів харчових продуктів,обґрунтовано переваги його використання для продуктів харчування. Розглянуто проблему безпечності активного та розумного паковання та регулювання його використання на прикладі законодавства ЄС, США та України. Визначено перешкоди на шляху поширення інноваційних технологій пакування в Україні та світі, а також перспективи їх подальшого розвитку.
Наукова новизна. На сьогодні активне та розумне паковання майже не доступне для українського споживача. Досі не було повністю розглянуто та структуровано перешкоди та перспективи розвитку цих видів паковання в умовах України.
Практична значимість. Суспільство постійно розвивається, а інноваційне паковання є результатом попиту споживачів на упаковку, яка є більш досконалою та креативною. Активне та розумне паковання – це результат інноваційного мислення в упаковці. Воно здатне покращити якість і безпечність харчових продуктів, а також повідомити споживачу актуальну інформацію про стан продукту, що змінюється в часі. Поширення нових технологій паковання є необхідним етапом розвитку торгівлі, що здатен задовольнити дедалі складніші вимоги споживача, зменшити кількість харчових відходів і зробити паковання якіснішим, безпечнішим і зручнішим.
Psycho Social Impact of Covid-19 on Saudi Children
Authors: Al-Shahry Fayz S
Published: March 2021

Aim: With over 60 million recorded cases, and the death of 2 million the world is indeed struggling with a serious public health threat, coronavirus. Lack of health awareness and directive particularly for children. Health care providers and parents are seriously worried for children as this is an unknown disease with no evidence-based to build up a sound clinical decision. Being restricted to a limited zone and ordered to a tightened precautions and safety roles are gated your psychological burden, multiple neuropsychiatric indices, and psychosocial stigma. School and active life is an essential part of the children's lifetime, while temporary school closures as a result of health crises are not only affecting the educational achievement but most importantly the physical -mental, and social aspects. The home detention for children is indeed upsetting and anticipated to have detrimental crucial effects on children’s physical and mental capacity and shatter the sense of growth normalcy that schools used to provide. The aim is to study the impact of Covid-19 quarantine consequences on psychosocial on Saudi children.

Method: A cross-sectional, analytical, comparative study using an anonymous electronic survey to the general population aged 3-15 years was done in which it showed parents-reported changes in the reaction, behaviors, and attitudes of their children related to psychosocial status during the Covid-19 lockdown.

Result: The behavior changes were noticed in the isolation, aggressiveness, physical activity, and reaction to learning. Families were noticed an attitude, behavior and psychological signs in almost 52, 58.57% respectively of their children. The family long-term impact expectations are negative in almost 40% of the population.

Conclusion: Almost 40-45% of the population showed the abnormal psychosocial impact of the Covid19 Quarantine consequences. The expected long-term impact may reach more than 40%. Estimates incidence in normal circumstances was 2-3% to 22%.
Editor Note Volume 3 Issue 1
Authors: Martins Ian James
Published: March 2021

The articles published in Volume 3, Issue 1 maintain the high standards for peer-reviewed journals. These articles are related to Pulmonary Tuberculosis, Animal Models, COVID-19 vaccines, Dentistry Data Analytics, and the Psychosocial Impact of COVID-19 in children. The effort and expertise of these authors contribute to clinical and medical research and is the cornerstone of the scientific process with relevance to peer-review by medical researchers and healthcare professionals. The research questions in these articles are important and appropriate to the journal and adhere to journal standards and to the top 10% of papers published in the medical field.
Reasons and Realities of Health and Geographical Inequality in India: A Study of Inter-State Variations
Authors: Dalip Kumar
Published: March 2021

The paper is an attempt to explain the global regional inequality of health indicators and regional variation among Indian states. This analysis will cover through a set of health indicators (mortality and morbidity) like crude birth rate (CBR), crude death rate (CDR), infant mortality rate (IMR), maternal mortality rate (MMR), life expectancy and total fertility rates (TFR). The paper also provides a comparison of public expenditures on health with that of health expenditure in the private sector in India with those of other countries. This article highlights the dimensions and extent of inequities health indicators. The analysis in this study suggests that much of the problem for low health status in these states is also due to low health expenditure which impacts adversely on the health indicators.
MANAGEMENT AUDIT OF THE PROCUREMENT PROCESS
Authors: Voloshina Elena Ivanovna
Published: March 2021

Optimizing the logistics systems of an organization is a rather difficult task, since the logistics and management processes are closely interrelated. The success of an organization depends more on the effectiveness of the interaction of its units with each other than on the activities of each unit separately. Therefore, it is necessary to integrate and bring into a single center management decisions on the selection of suppliers, the organization of the procurement process, the formation of stocks, the organization of the warehouse operations and transportation. This is precisely what the goal is set for when conducting a management audit of an organization’s procurement system.
The aim of the study is to form a methodology for management audit of a logistics system as a basis for managing the effectiveness of the organization’s procurement process.
In the course of the research, the essence and necessity of a management audit of the procurement process were revealed. The audit methodology was formed, the positive initiatives of the organization were reflected during the management audit of the procurement process. It was established that the management audit of procurement continues to develop and strengthen, since it contributes to the formation of coordinating, supervisory and control measures of the procurement process, building a model of financial and personnel support for procurement in accordance with industry standards, optimizing the supplier management system and forming criteria for determining competition, organizing the process of documenting the procurement process, the formation of rules and delegation of authority in accordance with the evolving business model and strategic goals of the organization.
IMPROVING THE ACCOUNTING OF ADMINISTRATIVE EXPENSES OF COMPANIES ENGAGED IN MULTIPLE ACTIVITIES
Authors: Grekova Vita Anatolievna
Published: March 2021

Production costs and costs of selling products (works, services) are the main objects of on-farm control. Any change in them when a company conducts several activities leads to an incorrect determination of profit for each of the activities. Thus, the risk of material misstatement of production costs and sales costs increases, and hence the adoption on their basis of incorrect decisions on the future economic activities of the company. Organizationally and methodically correctly organized accounting of general business costs makes it possible to provide reliable information on the formation of the actual cost of finished products and goods. The paper analyzes unified approaches to the application of the Chart of Accounts for the financial and economic activities of organizations and the reflection of the facts of economic activity on the accounts of accounting, enshrined in the instructions for using the chart of accounts for the financial and economic activities of organizations. The analysis made it possible to identify a methodological error in the accounting of administrative and managerial expenses that arises when combining types of production activities with types of trading activities. An assessment of the information that the instructions on the use of the chart of accounts of the financial and economic activities of organizations on account 26 «General business expenses» and the actual data of the current accounting of a number of organizations that simultaneously carry out production and trade types of activities are recommended to summarize. The obtained result confirmed the overestimation of general business expenses while underestimating the costs of selling such economic entities. We see the prospect of further investigation of the problem in the elimination of the identified methodological error in accounting for administrative and management expenses with the introduction of adjustments to the instructions for using the chart of accounts of financial and economic activities of organizations.
IMPACT OF THE CORONAVIRUS PANDEMIC ON THE RUSSIAN BANKING SYSTEM
Authors: Yagupova Ekaterina Anatolyevna
Published: March 2021

The article deals with the current topic of the development of the Russian banking system in the context of the coronavirus pandemic. The current state of the banking sector and the activities of individual credit institutions are analyzed. The threat of a pandemic impact on the state’s banking sector is being studied. Taking into account the current situation, problems arise in the activity of banks, including the lack of full communication between credit institutions and customers– one of the most important factors in the development of banking business. It is quite difficult to operate remotely — most businesses are based on personal communication between employees and customers. The main problem and difference between the current situation and past crises is not the economic nature of the current crisis. Therefore, it is quite difficult to assess its progress and the consequences of the pandemic. The situation will depend on how widespread the COVID-19 pandemic is and how the authorities will respond to it. The consequences of a pandemic are unpredictable in their duration and impact. It is obvious that the country is waiting for a drop in production and this is a serious blow. How fast the economic recovery will be depends on the duration of the pandemic. The measures taken by the government to support the population (issuance of zero loans and registration of credit holidays, etc.), today will cause damage to the banking sector by about 400 billion rubles. If we take into account last year’s net profit of the country’s banks, which amounted to 1.7 trillion rubles, the banking system will withstand this blow. The main risk for banks will be non-repayment of loans by businesses, deterioration of the loan portfolio. This may lead to a crisis in some sectors of the economy, whose enterprises are borrowers. According to the most negative estimates of experts, the losses of the banking sector may amount to about 900 billion rubles. The crisis triggered by the coronavirus pandemic will be felt by the country’s banks in the next six months. Banking organizations will need financial support from the state. Some financial institutions will not survive without state aid. In the current situation associated with the COVID-19 epidemic, banking organizations are still only underperforming. After the pandemic, the country’s banks, as well as their clients, will find themselves in a new reality. The economic situation in the country will be different. Entire sectors of the economy may be transformed. Some banking organizations will close, and the remaining financial institutions will develop remote services, which they switched to during the coronavirus period. It is quite difficult to predict what will happen to the rates of loans and deposits and the ruble exchange rate. This depends on many factors. One thing is clear-the world will not be the same.