bluuebunny/crossref_metadata_2025 huggingface dataset:
Biomaterials Functionalized with Inflammasome Inhibitors—Premises and Perspectives
Authors: Vinţeler Norina , Feurdean Claudia Nicoleta , Petkes Regina , Barabas Reka , Boşca Bianca Adina , Muntean Alexandrina , Feștilă Dana , Ilea Aranka
Published: January 2024

This review aimed at searching literature for data regarding the inflammasomes’ involvement in the pathogenesis of oral diseases (mainly periodontitis) and general pathologies, including approaches to control inflammasome-related pathogenic mechanisms. The inflammasomes are part of the innate immune response that activates inflammatory caspases by canonical and noncanonical pathways, to control the activity of Gasdermin D. Once an inflammasome is activated, pro-inflammatory cytokines, such as interleukins, are released. Thus, inflammasomes are involved in inflammatory, autoimmune and autoinflammatory diseases. The review also investigated novel therapies based on the use of phytochemicals and pharmaceutical substances for inhibiting inflammasome activity. Pharmaceutical substances can control the inflammasomes by three mechanisms: inhibiting the intracellular signaling pathways (Allopurinol and SS-31), blocking inflammasome components (VX-765, Emricasan and VX-740), and inhibiting cytokines mediated by the inflammasomes (Canakinumab, Anakinra and Rilonacept). Moreover, phytochemicals inhibit the inflammasomes by neutralizing reactive oxygen species. Biomaterials functionalized by the adsorption of therapeutic agents onto different nanomaterials could represent future research directions to facilitate multimodal and sequential treatment in oral pathologies.
Novel Advancements in COVID-19 and Neuroscience
Authors: Simonetti Alessio , Bernardi Evelina , Sani Gabriele
Published: January 2024

From an initial cluster of cases reported in Wuhan, the SARS-Cov-2 infection has since spread globally, causing a pandemic that began on 11 March 2020 [...]
The Impact of Chemotherapy and Transforming Growth Factor-β1 in Liver Regeneration after Hepatectomy among Colorectal Cancer Patients
Authors: Račkauskas Rokas , Lukšaitė-Lukštė Raminta , Stulpinas Rokas , Baušys Augustinas , Paškonis Marius , Kvietkauskas Mindaugas , Sokolovas Vitalijus , Laurinavičius Arvydas , Strupas Kęstutis
Published: January 2024

An ongoing debate surrounds the impact of chemotherapy on post-hepatectomy liver regeneration in patients with colorectal cancer liver metastases (CRLM), with unclear regulatory mechanisms. This study sought to delve into liver regeneration post-resection in CRLM patients, specifically examining the roles of hepatocyte growth factor (HGF) and transforming growth factor β1 (TGF-β1). In this longitudinal observational study, 17 patients undergoing major liver resection for CRLM and 17 with benign indications as controls were enrolled. Liver regeneration within 30 postoperative days was assessed via CT, considering clinicopathological characteristics, liver enzymes, liver stiffness by elastography, and the impact of HGF and TGF-β1 on liver regeneration. The results revealed that the control group exhibited significantly higher mean liver regeneration volume (200 ± 180 mL) within 30 days postoperatively compared to the CRLM group (72 ± 154 mL); p = 0.03. Baseline alkaline phosphatase (AP) and TGF-β1 blood levels were notably higher in the CRLM group. Immunohistochemical analysis indicated a higher proportion of CRLM patients with high TGF-β1 expression in liver tissues compared to the control group (p = 0.034). Correlation analysis showed that resected liver volume, baseline plasma HGF, AP, and albumin levels significantly correlated with liver regeneration volume. However, in multivariable analysis, only resected liver volume (β: 0.31; 95% CI: 0.14–0.47, p = 0.01) remained significant. In conclusion, this study highlights compromised liver regeneration in CRLM patients post-chemotherapy. Additionally, these patients exhibited lower serum TGF-β1 levels and reduced TGF-β1 expression in liver tissue, suggesting TGF-β1 involvement in mechanisms hindering liver regeneration capacity following major resection after chemotherapy.
Risk of Type 2 Diabetes in University Students at the University of Extremadura: A Cross-Sectional Study
Authors: Alfageme-García Pilar , Basilio-Fernández Belinda , Ramírez-Durán María del Valle , Gómez-Luque Adela , Jiménez-Cano Víctor Manuel , Fabregat-Fernández Juan , Alonso Vicente Robles , Clavijo-Chamorro María Zoraida , Hidalgo-Ruíz Sonia
Published: January 2024

The prevalence of type 2 diabetes is increasing worldwide. The aim of our study was to detect people susceptible to DM among a university population aged 18 to 45 years and analyze the existence of modifiable risk factors in order to implement prevention programs, in addition to analyzing BMI data related to the variables under study. We proposed a descriptive, cross-sectional study following the recommendations of cross-sectional studies (STROBE), with a sample of 341 subjects, students enrolled at the University of Extremadura, carried out by two researchers. The research protocol was approved by the Bioethics Committee of the University of Extremadura (165/2021). The study considered the Findrisk questionnaire in Spanish, validated by the Blackboard Study, a stadiometer to measure height, a bioimpedance meter to evaluate weight and body composition parameters, and a blood pressure monitor to measure blood pressure. The results indicated that the participants had a low risk of suffering T2DM. The highest Findrisk test scores were found in those with a BMI value above 25, lower physical activity, poor dietary intake of fruits and vegetables, and increased fat mass. Our future research will be the implementation of T2DM prevention programs, acting on modifiable factors.
Common and Potential Emerging Foodborne Viruses: A Comprehensive Review
Authors: Olaimat Amin N. , Taybeh Asma’ O. , Al-Nabulsi Anas , Al-Holy Murad , Hatmal Ma’mon M. , Alzyoud Jihad , Aolymat Iman , Abughoush Mahmoud H. , Shahbaz Hafiz , Alzyoud Anas , Osaili Tareq , Ayyash Mutamed , Coombs Kevin M. , Holley Richard
Published: January 2024

Human viruses and viruses from animals can cause illnesses in humans after the consumption of contaminated food or water. Contamination may occur during preparation by infected food handlers, during food production because of unsuitably controlled working conditions, or following the consumption of animal-based foods contaminated by a zoonotic virus. This review discussed the recent information available on the general and clinical characteristics of viruses, viral foodborne outbreaks and control strategies to prevent the viral contamination of food products and water. Viruses are responsible for the greatest number of illnesses from outbreaks caused by food, and risk assessment experts regard them as a high food safety priority. This concern is well founded, since a significant increase in viral foodborne outbreaks has occurred over the past 20 years. Norovirus, hepatitis A and E viruses, rotavirus, astrovirus, adenovirus, and sapovirus are the major common viruses associated with water or foodborne illness outbreaks. It is also suspected that many human viruses including Aichi virus, Nipah virus, tick-borne encephalitis virus, H5N1 avian influenza viruses, and coronaviruses (SARS-CoV-1, SARS-CoV-2 and MERS-CoV) also have the potential to be transmitted via food products. It is evident that the adoption of strict hygienic food processing measures from farm to table is required to prevent viruses from contaminating our food.
Numerical Simulation of the Stability of Low Viscosity Ratio Viscoelastic Lid-Driven Cavity Flow Based on the Log-Conformation Representation (LCR) Algorithm
Authors: Ke Lingjie , Wang Qikun
Published: January 2024

Log-Conformation Representation (LCR) method effectively enhances the stability of viscoelastic fluid flow driven by a cavity at high Wi numbers. However, its stability is relatively poor under low viscosity ratio conditions. In this study, three momentum equation stabilization algorithms (Both-Sides-Diffusion, Discrete Elastic Viscous Split Stress-Vorticity, and velocity–stress coupling) were tested and compared in OpenFOAM to assess their stabilizing effects on the LCR method under low viscosity ratio conditions. The evaluation was based on changes in average kinetic energy and the maximum critical time step. The results indicate that the different momentum equation stabilization algorithms improve the numerical oscillations observed in the numerical simulation of low viscosity ratio cavity-driven flow to varying extents. This enables a reduction in the viscosity ratio that can be stably simulated by 0.03 to 0.15. Furthermore, these cases using the momentum equation stabilization algorithms require time steps that are 33% to 100% shorter than those of the original cases. This demonstrates the promoting effect of the additional diffusion term in the momentum equation on stability under low viscosity ratio conditions. The combination of LCR and velocity–stress coupling was used to analyze the impact of viscosity ratios on velocity, logarithmic conformation tensor, and average kinetic energy. As the viscosity ratio decreases, the contribution of fluid elasticity increases, resulting in more pronounced variations in velocity and stress. However, the viscosity ratio has little effect on the stress boundary layer at the top cover and corners. Under conditions with the same Wi number, the average kinetic energy decreases as the viscosity ratio decreases until stability is achieved.
Employing Atomic Force Microscopy (AFM) for Microscale Investigation of Interfaces and Interactions in Membrane Fouling Processes: New Perspectives and Prospects
Authors: Wei Mohan , Zhang Yaozhong , Wang Yifan , Liu Xiaoping , Li Xiaoliang , Zheng Xing
Published: January 2024

Membrane fouling presents a significant challenge in the treatment of wastewater. Several detection methods have been used to interpret membrane fouling processes. Compared with other analysis and detection methods, atomic force microscopy (AFM) is widely used because of its advantages in liquid-phase in situ 3D imaging, ability to measure interactive forces, and mild testing conditions. Although AFM has been widely used in the study of membrane fouling, the current literature has not fully explored its potential. This review aims to uncover and provide a new perspective on the application of AFM technology in future studies on membrane fouling. Initially, a rigorous review was conducted on the morphology, roughness, and interaction forces of AFM in situ characterization of membranes and foulants. Then, the application of AFM in the process of changing membrane fouling factors was reviewed based on its in situ measurement capability, and it was found that changes in ionic conditions, pH, voltage, and even time can cause changes in membrane fouling morphology and forces. Existing membrane fouling models are then discussed, and the role of AFM in predicting and testing these models is presented. Finally, the potential of the improved AFM techniques to be applied in the field of membrane fouling has been underestimated. In this paper, we have fully elucidated the potentials of the improved AFM techniques to be applied in the process of membrane fouling, and we have presented the current challenges and the directions for the future development in an attempt to provide new insights into this field.
Process Optimization Method for Reducing the Thickness Difference of Cathode Foil for Power Batteries
Authors: Zuo Xiaogang , Lv Zhimin
Published: January 2024

The rolling process of aluminum foil is subject to the issue of variable thickness, which has a substantial impact on its performance. The thickness of the aluminum foil is influenced by various factors, including the magnitude of the bending force, the distance between the rollers, the thermal expansion of the roller, and the acceleration of the rolling mill. To address the issue of quick fluctuations in bending force during the rolling process, either a positive bending force or a slight negative bending force is employed. The adjustment factor for the bending force applied to the roll gap is set to a value of 1.0. Upon conducting a comparative analysis of the thermal expansion curves of the model with varying thermal expansion coefficients, it was ascertained that an optimized coefficient of 1.71 yielded the most favorable results. The roll gap is adjusted using a sixth power equation to accommodate the rolling of materials with both low and high pressure. Subsequently, the roll is elevated by 0.2 mm and 0.18 mm for the entire duration. The findings from the rolling experiments indicate that the optimization of the process leads to a notable reduction in the variance of aluminum foil thickness.
Corrosion Behavior of Titanium Alloys (Ti CP2, Ti-6Al-2Sn-4Zr-2Mo, Ti-6Al-4V and Ti Beta-C) with Anodized and Exposed in NaCl and H2SO4 Solutions
Authors: Gaona-Tiburcio Citlalli , Jáquez-Muñoz Jesús Manuel , Nieves-Mendoza Demetrio , Maldonado-Bandala Erick , Lara-Banda Maria , Lira-Martinez Manuel Alejandro , Reyes-Blas Hortensia , Baltazar-Zamora Miguel Ángel , Landa-Ruiz Laura , Lopez-Leon Luis Daimir , Almeraya-Calderon Facundo
Published: January 2024

Nowadays, different industries, such as the aerospace and biomedical industries, prefer using Ti alloys due to their excellent anti-corrosion properties and ability to generate a TiO2 oxide layer; this induces the use of anodization to increase the useful life of components. The aim of this work is to characterize the electrochemical effect of anodizing treatment on titanium alloys (Ti CP2, Ti-6Al-2Sn-4Zr-2Mo, Ti-6Al-4V, and Ti Beta-C) in NaOH and KOH at 1 M, applying a current density of 0.0025 A/cm2. The electrochemical techniques employed were electrochemical noise (EN) and electrochemical impedance spectroscopy (EIS), supported by ASTM G199 and ASTM G106 in electrolytes of NaCl and H2SO4 at 3.5 wt. % as a simulation of marine and industrial atmospheres. Also, the anodized transversal section and surface morphology were characterized by a scanning electron microscope (SEM). The results of both electrochemical techniques indicated that Ti-6Al-2Sn-4Zr-2Mo anodized in NaOH presented the best properties against corrosion, and the thickness of the oxide was the biggest.
Distinct Evidence of Hydrogen-Enhanced Defect Formation on Pre-Strained Nickel Alloy 625 during In Situ Electrochemical Nanoindentation Test
Authors: Soundararajan Chandrahaasan K. , Lu Xu , Wang Dong , Vinogradov Alexei
Published: January 2024

In the present work, in situ electrochemical nanoindentation was utilized to investigate the hydrogen effect on the nanomechanical properties of tensile pre-strained nickel alloy (0%, 5% and 20%). The study reveals that hydrogen-induced hardening occurs during cathodic polarization due to hydrogen incorporation and softening behavior during anodic polarization; this is due to the irreversible microstructure modification induced in the presence of hydrogen solutes. Their respective contributions were quantified by fitting the elastoplastic part of the load-displacement data. In addition, the differences in their plastic behaviors were investigated in detail by examining the dislocation structure underneath the indents. This study aims to shed light on hydrogen’s interaction with pre-existing defects.
A First-Time Investigation into Ecofriendly and Biocompatible Mg-Se Binary System for a Greener Earth
Authors: Johanes Michael , Sonawane Vasuudhaa , Gupta Manoj
Published: January 2024

In this study, the Mg-15Se binary system was, for the first time, investigated and synthesized using the powder metallurgy (PM) method, including microwave sintering and hot extrusion. The resulting material was shown to possess visible pores with a porosity of 2.91%, higher than other Mg materials synthesized using this method in the literature. Despite this, the material not only exhibited a comparable corrosion response with pure Mg but also a significantly superior mechanical response (76% greater damping capacity, 57% increase in hardness, and increases of 21%, 50%, and 51% for compressive yield strength, ultimate compressive strength, and fracture strain, respectively). Thus, this not only opens the door for future work concerning the addition of medicinal Se to nutritional Mg element and the optimization of process parameters but also could potentially be making inroads into the biomedical field with the use of selenium as a biomedical-oriented alloying element.
Advances in Additive Manufacturing and Their Applications
Authors: Berce Petru
Published: January 2024

Additive manufacturing (AM) has evolved rapidly in the last few years [...]
Structure and Properties of WC-Fe-Ni-Co Nanopowder Composites for Use in Additive Manufacturing Technologies
Authors: Krinitcyn Maksim , Svarovskaya Natalia V. , Rodkevich Nikolay , Ryumin Egor , Lerner Marat
Published: January 2024

In this work, the samples of the WC-Fe-Ni-Co composition were obtained and studied. Alloy NiCo 29-18 is used as a binder (Fe-Ni-Co). In this paper, a comparative analysis of the samples obtained using commercial micron-sized WC powder and the samples obtained is carried out using nano-WC synthesized via the electric explosion of wire (EEW) method. The samples were subjected to vacuum sintering, then their structure, density, and porosity, as well as microhardness and oxidation resistance, were studied. Five different additives were used to stabilize sintering: VC, Cr3C2, NbC, Y2O3, and Nd2O3. All these additives are described in the literature as additives that are used in the sintering of materials of the WC-Co system. Also, the samples from the WC-Fe-Ni-Co material were obtained using additive manufacturing technology with material extrusion. Bending strength and hardness of the additively fabricated samples were determined.
Fabrication of Micro Carbon Mold for Glass-Based Micro Hole Array
Authors: Lee Ui Seok , Sim Dae Bo , Lee Ji Hyo , Kim Bo Hyun
Published: January 2024

In glass molding to produce biochips with micro holes, cavities, and channels, it is important to machine micro molds. This study presents a novel process for fabricating micro pin arrays on carbon graphite, one of the glass molding materials. The micro pin array was used as a mold to fabricate a glass-based micro hole array. Using conventional micro endmill tools, machining micro-cylindrical pins requires complex toolpaths and is time-consuming. In order to machine micro pin arrays with high efficiency, a micro eccentric tool was introduced. Micro pin arrays with a diameter of 200 µm and a height of 200 µm were easily fabricated on graphite using the micro eccentric tool. In the machining of micro pin arrays using eccentric tools, the machining characteristics such as cutting force and tool wear were investigated.
Lithium Niobate MEMS Antisymmetric Lamb Wave Resonators with Support Structures
Authors: Zhang Yi , Jiang Yang , Tang Chuying , Deng Chenkai , Du Fangzhou , He Jiaqi , Hu Qiaoyu , Wang Qing , Yu Hongyu , Wang Zhongrui
Published: January 2024

The piezoelectric thin film composed of single-crystal lithium niobate (LiNbO3) exhibits a remarkably high electromechanical coupling coefficient and minimal intrinsic losses, making it an optimal material for fabricating bulk acoustic wave resonators. However, contemporary first-order antisymmetric (A1) Lamb mode resonators based on LiNbO3 thin films face specific challenges, such as inadequate mechanical stability, limited power capacity, and the presence of multiple spurious modes, which restrict their applicability in a broader context. In this paper, we present an innovative design for A1 Lamb mode resonators that incorporates a support-pillar structure. Integration of support pillars enables the dissipation of spurious wave energy to the substrate, effectively mitigating unwanted spurious modes. Additionally, this novel approach involves anchoring the piezoelectric thin film to a supportive framework, consequently enhancing mechanical stability while simultaneously improving the heat dissipation capabilities of the core.
Wind Tunnel Characterization of a Graphene-Enhanced PEDOT:PSS Sensing Element for Aircraft Ice Detection Systems
Authors: Farina Dario , Mazio Marco , Machrafi Hatim , Queeckers Patrick , Iorio Carlo Saverio
Published: January 2024

This study details the development and validation of a graphene-based ice detection system, designed to enhance flight safety by monitoring ice accumulation on aircraft surfaces. The system employs a semiconductive polymer (PEDOT:PSS) with graphene electrodes, interpreting resistance changes to detect water impact and ice formation in real time. The sensor’s performance was rigorously tested in a wind tunnel under various temperature and airflow conditions, focusing on resistance signal dependency on air temperature and phase change. The results demonstrate the sensor’s ability to distinguish water droplet impacts from ice formation, with a notable correlation between resistance signal amplitude and water droplet impacts leading to ice accretion. Further analysis shows a significant relationship between air temperature and the resistance signal amplitude, particularly at lower temperatures beneficial to ice formation. This underlines the sensor’s precision in varied atmospheric conditions. The system’s compact design and accurate detection highlight its potential for improving aircraft ice monitoring, offering a path toward a robust and reliable ice detection system.
Fabrication and Characterization of 2D Nonlinear Structures Based on DAST Nanocrystals and SU-8 Photoresist for Terahertz Application
Authors: Pogosian Tamara , Ledoux-Rak Isabelle , Denisyuk Igor , Fokina Maria , Lai Ngoc Diep
Published: January 2024

We demonstrate a method for the realization of highly nonlinear optical 4-(4-dimethylaminostyryl)- 1-methylpyridinium tosylate (DAST) two-dimensional structures by a double-step technique. The desired polymeric structures were first fabricated by using the multiple exposure of the two-beam interference technique, and the DAST nanoscrystals were then prepared inside the air-voids of these photoresist templates, resulting in nonlinear periodic structures. The nonlinear properties were characterized by optical and scanning microscopies, as well as by second-harmonic generation technique. This nonlinear modulation is very promising for the enhancement of nonlinear conversion rates, such as terahertz generation, by using the quasi-phase matching technique.
The Solubility of Antimony (Sb) in Liquid Hydrocarbons and Its Implication for the Ore-Forming Process of Orogenic Antimony-Gold Deposits in Southern Tibet
Authors: Su Yue , Sun Xiaoming , Ding Zhengpeng
Published: January 2024

Orogenic antimony-gold deposits contribute significantly to the global antimony resource base. China’s orogenic antimony-gold deposits are primarily in southern Tibet. Investigations indicate that antimony combines and migrates with sulfur hydroxides in ore-forming fluids. Previous research on fluid inclusions in orogenic antimony-gold ores with sedimentary rock accommodation revealed the presence of organic inclusions, including liquid hydrocarbons, alongside common components such as CO2, H2O, CH4, and NaCl. However, the impact of liquid hydrocarbons on antimony migration and mineralization is still debatable. To investigate the transportability of antimony by liquid hydrocarbons in orogenic antimony ores, we selected n-dodecanethiol and n-dodecane as the subjects. We measured the solubility and occurrence form of antimony in these compounds at various temperatures and durations. The results indicate that after 5 and 10 days of reaction at 100 °C, the antimony concentrations in the n-dodecanethiol and n-dodecane groups were 67.44 ± 7.62 ppm, 75.15 ± 16.74 ppm, 1.40 ± 1.02 ppm, and 3.02 ± 3.09 ppm, respectively. At 150 °C for 5 and 10 days, the respective concentrations were 50.58 ± 5.39 ppm, 77.26 ± 45.20 ppm, 2.66 ± 3.08 ppm, and 2.41 ± 2.03 ppm. At 200 °C for 5 and 10 days, the corresponding concentrations were 339.76 ± 71.94 ppm, 218.97 ± 25.03 ppm and 6.53 ± 7.17 ppm, 2.27 ± 0.82 ppm (n = 3). The measured solubility of antimony in the n-dodecanethiol group increased gradually with rising temperature. The solubility of antimony in the n-dodecane group was low and notably inferior to that observed in the n-dodecanethiol group. X-ray photoelectron spectroscopy (XPS) analysis demonstrated a distinct thiol (R-SH) peak at 163.31 eV and compound peaks of antimony reacting with thiols at 162.06 and 160.87 eV. This suggests that antimony predominantly forms complexes with thiols for migration. Our findings suggest that specific liquid hydrocarbon components, predominantly thiols, can interact with antimony at metallogenic temperatures and persist in ore-forming fluids, facilitating migration and mineral enrichment. Earlier experimental studies on gold and crude oil have indicated that liquid hydrocarbons also play an essential role in the transportation and enrichment of gold during the formation of gold deposits, thus indicating that liquid hydrocarbons possess the considerable potential to act as an ore-forming fluid during orogenic antimony-gold deposit formation in southern Tibet.
Oolitic Limestone Induced by Photosynthetic Biofilms in the Xuzhuang Formation of Nangao Section, North China
Authors: Li Ruoxiang
Published: January 2024

The role of biofilms in the formation of ooids is a focal point of current research. This study synthesizes macroscopic data with microscopic observations to analyze the depositional environment and genesis of oolitic limestone within the Xuzhuang Formation at the Nangao section. Notably, cerebroid ooids with unique cortical morphologies have been discovered. Within the nucleus, cortex, and the lumps among the ooids, a high-density preservation of Girvanella has been identified. Clotted micrite structures have also been observed within the filler content. The findings suggest that phototrophic biofilms have facilitated the formation of oolitic limestone in this profile, offering direct evidence for the connection between the festooned cortical morphologies and biofilms. This study further questions the interpretation of clotted micrite structures as sponge remains. These insights significantly enhance our understanding of the causal factors behind ooid formation.
Continental Arc Plutonism in a Juvenile Crust: The Neoproterozoic Metagabbro-Diorite Complexes of Sinai, Northern Arabian-Nubian Shield
Authors: El-Bialy Mohammed Z. , Khedr Mohamed Z. , El-Bialy Bassil M. , Hassan Hatem F.
Published: January 2024

Based on new field, petrographic, and whole-rock geochemistry data, we investigated three discrete metagabbro-diorite complexes (MGDC) across the E-W Sinai to contribute to increasing knowledge of the evolution of the juvenile continental crust of the Neoproterozoic Arabian–Nubian Shield. The three MGDCs vary in the dominance of the gabbroic versus dioritic rock types among each of them. Gabbroids are distinguished into pyroxene-hornblende gabbros and hornblende gabbros, whereas dioritic rocks have been subdivided into diorites and quartz diorites. The studied MGDC rocks are almost metaluminous and possess prevalent calc-alkaline characteristics over subsidiary tholeiitic and alkaline affinities. The most distinctive feature in the profiles of the investigated MGDCs on the N-MORB-normalized spider diagrams is the coincidence of stout negative Nb anomalies and projecting positive Pb spikes, which is typical of igneous rocks evolved in subduction zones. The three MGDC samples exhibit variably LREE-enriched patterns [(La/Yb)N = 4.92–18.55; av. = 9.04], either lacking or possessing weak to negligible positive and negative Eu anomalies. The calculated apatite and zircon crystallization temperatures reveal the earlier separation of apatite at higher temperatures, with the obvious possibility of two genetic types of apatite and zircon in the magma (cognate vs. xenocrystic) since both accessories have yielded very wide ranges of crystallization temperatures. The investigated MGDCs were formed in a continental arc setting, particularly a thick-crust arc (>39 km). The parent magmas comprised components derived from the melting of the mantle wedge, subducting oceanic lithosphere, and subducting overlying sediments. The mantle input was from a spinel–garnet transitional mantle source at a depth of ca. 75–90 km. The impact of slab-derived fluids was much greater than that of slab-derived melts, and so subduction-related fluids had a crucial effect on metasomatizing the partially melted mantle source. The parent mantle-derived magma has been subjected to substantial crustal contamination as a dominant mechanism of differentiation.
Distribution, Occurrence and Enrichment Causes of Sodium in Middle Jurassic Coal from Zhundong Coalfield, Xinjiang
Authors: Wang Yulong , Wang Wenfeng , Wang Wenlong , Duan Piaopiao , He Xin , Lu Qingfeng
Published: January 2024

The coal found in the Zhundong Coalfield is highly suitable for power generation and gasification. However, the high sodium content within the coal leads to severe boiler slagging and contamination. Additionally, sodium disperses into the gaseous phase to form haze, adversely affecting the local atmospheric environment. This study delved into the distribution and occurrence characteristics and enrichment causes of sodium in the coal, employing sequential extraction experiments and testing methods such as XRF, ICP-OES and SEM-EDS. The findings of this research indicate the following: (1) With the increasing burial depth of coal seams, there is a noticeable decrease in the sodium content within the coal. Sodium is primarily distributed within the coal seam, with higher concentrations observed in the upper portions of the same coal seam. Furthermore, the distribution of sodium within the epipedon, overlying rocks and coal seam also exhibits a decreasing trend. (2) Sodium primarily exists in a water-soluble state within coal seams, with H2O-Na accounting for over 70% of its composition. The ion-exchangeable sodium is higher than that in the roof, floor and gangue. Sodium exists in coal seams in both ionic and hydrated ionic forms. It is worth noting that the minerals within coal are not the primary carriers of sodium. (3) These coal seams were formed in a warm and humid shallow lake peat swamp environment, which is not significantly influenced by terrestrial or marine sources. The enrichment of sodium is primarily influenced by later hydrodynamic conditions.
Fabrication of NiFe-LDHs Modified Carbon Nanotubes as the High-Performance Sulfur Host for Lithium–Sulfur Batteries
Authors: Zhang Lingwei , Li Runlan , Yue Wenbo
Published: January 2024

Lithium–sulfur batteries offer the potential for significantly higher energy density and cost-effectiveness. However, their progress has been hindered by challenges such as the “shuttle effect” caused by lithium polysulfides and the volume expansion of sulfur during the lithiation process. These limitations have impeded the widespread adoption of lithium–sulfur batteries in various applications. It is urgent to explore the high-performance sulfur host to improve the electrochemical performance of the sulfur electrode. Herein, bimetallic NiFe hydroxide (NiFe-LDH)-modified carbon nanotubes (CNTs) are prepared as the sulfur host materials (NiFe-CNT@S) for loading of sulfur. On the one hand, the crosslinked CNTs can increase the electron conductivity of the sulfur host as well as disperse NiFe-LDHs nanosheets. On the other hand, NiFe-LDHs command the capability of strongly adsorbing lithium polysulfides and also accelerate their conversion, which effectively suppresses the shuttle effect problem in lithium polysulfides. Hence, the electrochemical properties of NiFe-CNT@S exhibit significant enhancements when compared with those of the sulfur-supported pure NiFe-LDHs (NiFe-LDH@S). The initial capacity of NiFe-CNT@S is reported to be 1010 mAh g−1. This value represents the maximum amount of charge that the material can store per gram when it is first synthesized or used in a battery. After undergoing 500 cycles at a rate of 2 C (1 C = 1675 mA g−1), the NiFe-CNT@S composite demonstrates a sustained capacity of 876 mAh g−1. Capacity retention is a measure of how well a battery or electrode material can maintain its capacity over repeated charge–discharge cycles, and a higher retention percentage indicates better durability and stability of the material.
On the Stability of Electrohydrodynamic Jet Printing Using Poly(ethylene oxide) Solvent-Based Inks
Authors: Ramon Alberto , Liashenko Ievgenii , Rosell-Llompart Joan , Cabot Andreu
Published: January 2024

Electrohydrodynamic (EHD) jet printing of solvent-based inks or melts allows for the producing of polymeric fiber-based two- and three-dimensional structures with sub-micrometer features, with or without conductive nanoparticles or functional materials. While solvent-based inks possess great material versatility, the stability of the EHD jetting process using such inks remains a major challenge that must be overcome before this technology can be deployed beyond research laboratories. Herein, we study the parameters that affect the stability of the EHD jet printing of polyethylene oxide (PEO) patterns using solvent-based inks. To gain insights into the evolution of the printing process, we simultaneously monitor the drop size, the jet ejection point, and the jet speed, determined by superimposing a periodic electrostatic deflection. We observe printing instabilities to be associated with changes in drop size and composition and in the jet’s ejection point and speed, which are related to the evaporation of the solvent and the resulting drying of the drop surface. Thus, stabilizing the printing process and, particularly, the drop size and its surface composition require minimizing or controlling the solvent evaporation rate from the drop surface by using appropriate solvents and by controlling the printing ambient. For stable printing and improved jet stability, it is essential to use polymers with a high molecular weight and select solvents that slow down the surface drying of the droplets. Additionally, adjusting the needle voltages is crucial to prevent instabilities in the jet ejection mode. Although this study primarily utilized PEO, the general trends observed are applicable to other polymers that exhibit similar interactions between solvent and polymer.
Growth of Wide-Bandgap Monolayer Molybdenum Disulfide for a Highly Sensitive Micro-Displacement Sensor
Authors: Wang Shaopeng , Huang Jiahai , Wu Yizhang , Hao Huimin
Published: January 2024

Two-dimensional (2D) piezoelectric semiconductor materials are garnering significant attention in applications such as intelligent sensing and energy harvesting due to their exceptional physical and chemical properties. Among these, molybdenum disulfide (MoS2), a 2D wide-bandgap semiconductor, exhibits piezoelectricity in odd-layered structures due to the absence of an inversion symmetry center. In this study, we present a straightforward chemical vapor deposition (CVD) technique to synthesize monolayer MoS2 on a Si/SiO2 substrate, achieving a lateral size of approximately 50 µm. Second-harmonic generation (SHG) characterization confirms the non-centrosymmetric crystal structure of the wide-bandgap MoS2, indicative of its piezoelectric properties. We successfully transferred the triangular MoS2 to a polyethylene terephthalate (PET) flexible substrate using a wet-transfer method and developed a wide-bandgap MoS2-based micro-displacement sensor employing maskless lithography and hot evaporation techniques. Our testing revealed a piezoelectric response current of 5.12 nA in the sensor under a strain of 0.003% along the armchair direction of the monolayer MoS2. Furthermore, the sensor exhibited a near-linear relationship between the piezoelectric response current and the strain within a displacement range of 40–100 µm, with a calculated response sensitivity of 1.154 µA/%. This research introduces a novel micro-displacement sensor, offering potential for advanced surface texture sensing in various applications.
Boosting Piezocatalytic Performance of BaTiO3 by Tuning Defects at Room Temperature
Authors: An Donghui , Liang Renhong , Liu Hua , Zhou Chao , Ye Mao , Zheng Renkui , Li Han , Ke Shanming
Published: January 2024

Defect engineering constitutes a widely-employed method of adjusting the electronic structure and properties of oxide materials. However, controlling defects at room temperature remains a significant challenge due to the considerable thermal stability of oxide materials. In this work, a facile room-temperature lithium reduction strategy is utilized to implant oxide defects into perovskite BaTiO3 (BTO) nanoparticles to enhance piezocatalytic properties. As a potential application, the piezocatalytic performance of defective BTO is examined. The reaction rate constant increases up to 0.1721 min−1, representing an approximate fourfold enhancement over pristine BTO. The effect of oxygen vacancies on piezocatalytic performance is discussed in detail. This work gives us a deeper understanding of vibration catalysis and provides a promising strategy for designing efficient multi-field catalytic systems in the future.
Enhanced TiO2/SiCx Active Layer Formed In Situ on Coal Gangue/Ti3C2 MXene Electrocatalyst as Catalytic Integrated Units for Efficient Li-O2 Batteries
Authors: Sun Zhihui , Zhou Nan , Li Meng , Huo Binbin , Zeng Kai
Published: January 2024

The pursuit of efficient cathode catalysts to improve cycle stability at ultra-high rates plays an important role in boosting the practical utilization of Li-O2 batteries. Featured as industrial solid waste, coal gangue with rich electrochemical active components could be a promising candidate for electrocatalysts. Here, a coal gangue/Ti3C2 MXene hybrid with a TiO2/SiCx active layer is synthesized and applied as a cathode catalyst in Li-O2 batteries. The coal gangue/Ti3C2 MXene hybrid has a tailored amorphous/crystalline heterostructure, enhanced active TiO2 termination, and a stable SiCx protective layer; thereby, it achieved an excellent rate stability. The Li-O2 battery, assembled with a coal gangue/Ti3C2 MXene cathode catalyst, was found to obtain a competitive full discharge capacity of 3959 mAh g−1 and a considerable long-term endurance of 180 h (up to 175 cycles), with a stable voltage polarization of 1.72 V at 2500 mA g−1. Comprehensive characterization measurements (SEM, TEM, XPS, etc.) were applied; an in-depth analysis was conducted to reveal the critical role of TiO2/SiCX active units in regulating the micro-chemical constitution and the enhanced synergistic effect between coal gangue and Ti3C2 MXene. This work could provide considerable insights into the rational design of catalysts derived from solid waste gangue for high-rate Li-O2 batteries.
Global Leadership Initiative on Malnutrition-Diagnosed Malnutrition in Lung Transplant Candidates
Authors: Calañas-Continente Alfonso , Gutiérrez-Botella Jesús , García-Currás Julia , Cobos Mª Jesús , Vaquero José Manuel , Herrera Aura , Molina Mª José , Gálvez Mª Ángeles
Published: January 2024

Background and aims: Malnutrition in lung transplantation (LT) candidates increases postoperative morbidity and mortality. Early diagnosis of malnutrition could attenuate adverse prognostic factors. This study aimed to assess the prevalence of nutritional risk and malnutrition using GLIM criteria in LT candidates and clinically characterize those with malnutrition. Methods: A prospective longitudinal study was conducted from 2000 to 2020 of LT candidates who underwent complete nutritional assessment (nutritional screening, anthropometry, bioelectrical impedance, blood laboratory tests and malnutrition diagnosis using GLIM criteria). Results: Obstructive diseases (45.6%), interstitial diseases (36.6%) and cystic fibrosis/non-cystic fibrosis bronchiectasis (15.4%) were the main conditions assessed for LT. Of the 1060 candidates evaluated, 10.6% were underweight according to BMI, 29% were at risk of malnutrition and 47% were diagnosed with malnutrition using GLIM criteria. Reduced muscle mass was the most frequent GLIM phenotypic criterion. Malnutrition was more prevalent in patients with cystic fibrosis/non-cystic fibrosis bronchiectasis (84.5%) and obstructive (45.4%) and interstitial (31.3%) diseases. GLIM criteria detected some degree of malnutrition in all diseases requiring LT and identified patients with higher CRP levels and worse respiratory function, anthropometric measurements and visceral protein and lipid profiles. Conclusions: LT candidates present a high prevalence of malnutrition using the GLIM algorithm. GLIM criteria detected malnutrition in all diseases requiring LT and defined patients with worse clinical-analytical profiles.
Exploring Lifestyle and Dietary Patterns in Pregnancy and Their Impact on Health: A Comparative Analysis of Two Distinct Groups 10 Years Apart
Authors: Mitran Andreea-Maria , Gherasim Andreea , Niță Otilia , Mihalache Laura , Arhire Lidia Iuliana , Cioancă Oana , Gafițanu Dumitru , Popa Alina Delia
Published: January 2024

The significance of dietary patterns during pregnancy is highlighted by accumulating evidence, emphasizing their pivotal role in promoting a healthy pregnancy for both the mother and the child. This study aimed to assess the current dietary patterns of pregnant women, compare the energy and nutrient intake of two distinct groups with a 10-year interval, and identify changes in dietary patterns. EPIC FFQ was applied, and its data were interpreted with the FETA program version 6 (CAMB/PQ/6/1205). By means of principal component analysis, three different food patterns were identified in each study group: vegetarian, balanced, and traditional (2013); and prudent, vegetarian, and modern (2023). Analyzing the relationship between food groups and gestational weight, we found that gestational weight gain in 2013 was positively correlated with eggs and egg dishes and milk and milk products, whereas in 2023, gestational weight gain was positively correlated with fats and oils, non-alcoholic beverages, and the modern pattern. Additionally, in 2023, pre-gestational BMI correlated positively with eggs and egg dishes. The balanced pattern emerged as a predictor for a lower likelihood of inadequate gestational weight gain in both groups. Furthermore, normal and overweight pregnant women showed a reduced likelihood of excessive gestational weight gain.
The Neuroprotective Role of Quinoa (Chenopodium quinoa, Wild) Supplementation in Hippocampal Morphology and Memory of Adolescent Stressed Rats
Authors: Terreros Gonzalo , Pérez Miguel Ángel , Muñoz-LLancao Pablo , D’Espessailles Amanda , Martínez Enrique A. , Dagnino-Subiabre Alexies
Published: January 2024

Brain physiology and morphology are vulnerable to chronic stress, impacting cognitive performance and behavior. However, functional compounds found in food may alleviate these alterations. White quinoa (Chenopodium quinoa, Wild) seeds contain a high content of n-3 fatty acids, including alpha-linolenic acid. This study aimed to evaluate the potential neuroprotective role of a quinoa-based functional food (QFF) in rats. Prepubertal male Sprague-Dawley rats were fed with rat chow or QFF (50% rat chow + 50% dehydrated quinoa seeds) and exposed or not to restraint stress protocol (2 h/day; 15 days). Four experimental groups were used: Non-stressed (rat chow), Non-stressed + QFF, Stressed (rat chow) and Stressed + QFF. Weight gain, locomotor activity (open field), anxiety (elevated plus maze, light-dark box), spatial memory (Y-maze), and dendritic length in the hippocampus were measured in all animals. QFF intake did not influence anxiety-like behaviors, while the memory of stressed rats fed with QFF improved compared to those fed with rat chow. Additionally, QFF intake mitigated the stress-induced dendritic atrophy in pyramidal neurons located in the CA3 area of the hippocampus. The results suggest that a quinoa-supplemented diet could play a protective role in the memory of chronically stressed rats.
Development and Validation of a Method of Body Volume and Fat Mass Estimation Using Three-Dimensional Image Processing with a Mexican Sample
Authors: García Flores Fabián Ituriel , Klünder Klünder Miguel , López Teros Miriam Teresa , Muñoz Ibañez Cristopher Antonio , Padilla Castañeda Miguel Angel
Published: January 2024

Body composition assessment using instruments such as dual X-ray densitometry (DXA) can be complex and their use is often limited to research. This cross-sectional study aimed to develop and validate a densitometric method for fat mass (FM) estimation using 3D cameras. Using two such cameras, stereographic images, and a mesh reconstruction algorithm, 3D models were obtained. The FM estimations were compared using DXA as a reference. In total, 28 adults, with a mean BMI of 24.5 (±3.7) kg/m2 and mean FM (by DXA) of 19.6 (±5.8) kg, were enrolled. The intraclass correlation coefficient (ICC) for body volume (BV) was 0.98–0.99 (95% CI, 0.97–0.99) for intra-observer and 0.98 (95% CI, 0.96–0.99) for inter-observer reliability. The coefficient of variation for kinetic BV was 0.20 and the mean difference (bias) for BV (liter) between Bod Pod and Kinect was 0.16 (95% CI, −1.2 to 1.6), while the limits of agreement (LoA) were 7.1 to −7.5 L. The mean bias for FM (kg) between DXA and Kinect was −0.29 (95% CI, −2.7 to 2.1), and the LoA was 12.1 to −12.7 kg. The adjusted R2 obtained using an FM regression model was 0.86. The measurements of this 3D camera-based system aligned with the reference measurements, showing the system’s feasibility as a simpler, more economical screening tool than current systems.
Ultrasound Muscle Evaluation for Predicting the Prognosis of Patients with Head and Neck Cancer: A Large-Scale and Multicenter Prospective Study
Authors: Fernández-Jiménez Rocío , García-Rey Silvia , Roque-Cuéllar María Carmen , Fernández-Soto María Luisa , García-Olivares María , Novo-Rodríguez María , González-Pacheco María , Prior-Sánchez Inmaculada , Carmona-Llanos Alba , Muñoz-Jiménez Concepción , Zarco-Rodríguez Felisa Pilar , Miguel-Luengo Luis , Boughanem Hatim , García-Luna Pedro Pablo , García-Almeida José Manuel
Published: January 2024

Head and neck cancer (HNC) is a prevalent and aggressive form of cancer with high mortality rates and significant implications for nutritional status. Accurate assessment of malnutrition in patients with HNC is crucial for optimizing treatment outcomes and improving survival rates. This study aimed to evaluate the use of ultrasound techniques for predicting nutritional status, malnutrition, and cancer outcomes in patients with HNC. A total of 494 patients with HNC were included in this cross-sectional observational study. Various tools and body composition measurements, including muscle mass and adipose tissue ultrasound evaluations, were implemented. Using regression models, we mainly found that high levels of RF-CSA (rectus femoris cross-sectional area) were associated with a decreased risk of malnutrition (as defined with GLIM criteria (OR = 0.81, 95% CI: 0.68–0.98); as defined with PG-SGA (OR = 0.78, 95% CI: 0.62–0.98)) and sarcopenia (OR = 0.64, 95% CI: 0.49–0.82) after being adjusted for age, sex, and BMI. To predict the importance of muscle mass ultrasound variables on the risk of mortality, a nomogram, a random forest, and decision tree models were conducted. RF-CSA was the most important variable under the random forest model. The obtained C-index for the nomogram was 0.704, and the Brier score was 16.8. With an RF-CSA < 2.7 (AUC of 0.653 (0.59–0.77)) as a split, the decision tree model classified up to 68% of patients as possessing a high probability of survival. According to the cut-off value of 2.7 cm2, patients with a low RF-CSA value lower than 2.7 cm2 had worse survival rates (p < 0.001). The findings of this study highlight the importance of implementing ultrasound tools, for accurate diagnoses and monitoring of malnutrition in patients with HNC. Adipose tissue ultrasound measurements were only weakly associated with malnutrition and not with sarcopenia, indicating that muscle mass is a more important indicator of overall health and nutritional status. These results have the potential to improve survival rates and quality of life by enabling early intervention and personalized nutritional management.