bluuebunny/crossref_metadata_2025 huggingface dataset:
What factors are associated with osteoarthritis after cementation for benign aggressive bone tumor of the knee joint: a systematic review and meta-analysis
Authors: Bayram Serkan , Salduz Ahmet , Yıldırım Ahmet Müçteba , Özkan Korhan , Eralp Levent , Özger Harzem
Published: March 2024

Background

The current systematic review aimed to answer the following questions: (i) Does extended curettage combined with the PMMA technique for the treatment of aggressive bone tumors around the knee led to the development of knee osteoarthritis? (ii) What factors are associated with osteoarthritis after bone cementation around the knee joint?

Methods

This study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. All electronic searches were performed on November 20, 2022, by a single researcher who evaluated the full texts of potentially eligible studies to determine inclusion. In these patients, the presence of osteoarthritis secondary to the surgical procedure was investigated. Data extracted included study type, characteristics of participants, sample size, gender, tumor site (femur or tibia), secondary osteoarthritis, tumor volume, distance from the joint cartilage, reoperation, follow-up time, Campanacci grade, and pathological fracture.

Results

In total, 11 studies comprising 204 patients were evaluated, and it was found that 61 (30%) patients developed knee osteoarthritis due to extensive curettage and bone cement application for benign aggressive tumor treatment. According to the results obtained based the random effects model with the 11 studies included in the meta-analysis, the mean odds ratio of development knee OA with the 95% CI was calculated as −2.77 (−3.711, −1.83), which was statistically significant (z = −5.79; P < 0.000).

Conclusion

The association of distance between the tumor and joint cartilage and development of osteoarthritis was not shown in this meta-analysis.

Level of Evidence

Level IV prognostic study.
Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample
Authors: Rosado Gretchen M , Martinez-Marchal Ana , Faykoo-Martinez Mariela , Holmes Melissa M , Brieño-Enríquez Miguel Angel
Published: March 2024

Recently, we described that in the naked mole rat ovary it is possible to study the ovarian reserve and the mitotic expansion of the germ cell postnatally. Herein, we show oocyte in vitro maturation and in vitro germ cell expansion using the same ovary.
Research on color matching model for wood panel furniture based on a back propagation neural network
Authors: Chen Yushu , Bian Jun
Published: March 2024

The wood furniture manufacturing industry continues in the direction of customized furniture. The analysis of color collocation is important for developing customized furniture. This study summarizes the common color collocation application area for porch cabinets. After selecting the appropriate color model, C # language was used to simulate a real scene setting experimental system in the Unity graphics engine. Colors were generated randomly in the corresponding area, and subjects evaluated the harmony. Then, the Python language was used to build the BP neural network model. The BP neural network models were trained using the Hue, Saturation, value (HSV) of the depicted colors and their corresponding scores. Finally, the evaluation model of color collocation and harmony was obtained. The model can be used to improve the prediction of color matching in customized furniture, which will promote enterprise productivity and industry development.
The impact of lignin content on the biodegradation of virgin paper pulps in soil and marine environment
Authors: Vikman Minna , Mikkelson Atte , Rautkoski Hille
Published: March 2024

Paper pulp is a lignocellulosic fibrous material used in the industrial production of paper and board products. In addition to cellulose and hemicellulose, paper pulp contains 1 to 20% lignin, depending on the raw materials and pulping process used. Lignin is a heterogenous aromatic polymer that is hydrophobic and more resistant to microbial degradation compared to the easily biodegradable cellulose and hemicellulose. In this study, the biodegradation of paper pulps containing varying amounts of lignin was examined in soil and marine environments using ISO testing methods. Lignin significantly reduced the mineralization of paper pulps to CO2 in both environmental conditions, and a strong inverse correlation between lignin content and the mineralization to CO2 was observed. A similar impact was observed with natural materials containing lignin, such as birch sawdust. Since the calculation of biodegradability in most ISO and EN standards is based solely on the concept of mineralization to CO2, materials containing lignin can receive poor values in these tests. The implications of this for standardized requirements of biodegradability and possible options to overcome testing deficiencies are discussed.
Raman Spectroscopic Analysis of the Microdeformation in Cellulosic Fibres
Authors:   Fibre Science and Technology Centre, Department of Paper Science, University of Manchester Institute of Science and Technology, Manchester, England, Hamad W.Y. , Eichhorn S. ,   Fibre Science and Technology Centre, Department of Paper Science, University of Manchester Institute of Science and Technology, Manchester, England
Published: March 2024

This paper addresses the application of Raman spectroscopic techniques to analyzing the deformation micromechanics of regenerated cellulosic fibres. In addition to information obtained on the macroscopic deformation, Raman spectroscopy enables the study of changes in internal strain associated with creep and recovery. The analysis of the mechanics of deformation of the fibres begins by following the response of the Raman-sensitive bands to external tensile loading. It is shown that the peak positions of the 895 cm-1 and 1095 cm-1 Raman bands shift to lower vibrational frequency under the action of tensile stress or strain due to the macroscopic deformation leading to direct stretching of the polymer molecules. Moreover, this approach makes possible the modelling of single fibre properties using simple viscoelastic dynamics; thereby relating the macromechanical properties of stress and strain to those obtained at the microscopic level via spectroscopy.
Changes in Fibre Wall Structure during Deﬁbration
Authors:   The Finnish Pulp and Paper Research Institute (KCL), Lammi Tuulikki , Heikkurinen Annikki ,   The Finnish Pulp and Paper Research Institute (KCL)
Published: March 2024

Development of earlywood and latewood fibres was investigated to find out how morphologically different fibres undergo delamination. Fibre fractions rich in earlywood and latewood, were separated from mechanical pulps using a hydrocyclone and refined further in awing defibrator. Changes in fibre structure due to defibration were studied using microscopy techniques that included measurement of fibre stiffness, fibre wall thickness and external fibre surface. Before refining, the latewood fibres were stiff and their external fibre wallswere poorly developed. Refining reduced the stiffness of both fibre types. The stiffness of latewood fibres decreased to around that of unrefined earlywood fibres, andthe external walls of latewood fibres became fibrillated. The wall thickness of both earlywood and latewood fibres was reduced only slightly. Although the tensile and tear indices of sheets made of late wood fibres were improved by refining, the tensile index of flexible latewood fibres was only half of that measured for unrefined earlywood fibres. This indicates that there are fibre properties other than stiffness which must be changed in order to get latewood fibres to bond and conform properly.
Next-Generation Exterior Painting: A Prototype Model for High-Rise Buildings with ESP32 Wireless Control
Authors: Mohanasundaram Anthony , Shakeel Mohammed
Published: March 2024

This paper addresses the need for innovative solutions in exterior painting processes for high-rise buildings. The intention is to develop a prototype model that not only automates the painting procedure but also enhances efficiency, safety, and the overall quality of the process. The methodology involves the integration of ESP32 wireless control technology, allowing for automation through either Wi-Fi or cloud control. The key components of the model include a 240V, 1hp single-phase hoisted motor for vertical movement along the building façade and a 12V PMDC square geared motor for the operation of painting arms that apply paint to the wall. A contactless painting approach is adopted using a sprayer instead of traditional brushes or rollers. The results of the model's painting operations demonstrate significant reductions in time and costs compared to traditional methods, along with improvements in safety and overall painting quality. Notably, the model is designed to adapt to diverse climate conditions and accommodate various building sizes and shapes. This proposed automated exterior painting model holds immense potential for revolutionizing conventional practices, providing a safer, more efficient, and cost-effective solution for a wide range of building structures.
Human Leucocyte Antigen Class II Risk and Protective Alleles in Women with Cervical Intraepithelial Neoplasia
Authors: Plisko Olga , Žodžika Jana , Jermakova Irina , Liepniece-Karele Inta , Eglīte Jeļena , Rezeberga Dace
Published: March 2024

Background: Persistent human papillomavirus (HPV) infection is a necessary cause for development of cervical precancerous lesions and cervical cancer, however, only a small percentage of women progress to cervical cancer. The local immune response, determined, among other factors, by Human Leucocyte Antigen (HLA) genes, is thought to be significant. Still the results of genome studies are inconsistent and differ between ethnical populations.  The aim of the study was to assess an association between HLA-DQA1*; DQB1*; DRB1* allele’s genetic variants between women with cervical precancerous lesions and healthy controls in Latvia.Materials and methods: From January until April 2017 we enrolled 84 consecutive patients referred for colposcopy to Riga East University Hospital (Latvia) due to abnormal cervical cytology results. 57 women who came for a regular check-up and had normal cytology smears were included in the control group. Material from the cervix was taken for subsequent HLA genotyping of 13 DRB1*, 8 DQA1*, and 12 DQB1* alleles. Colposcopy was performed on all participants. In case of visual suspicion for CIN cervical biopsy was done.Results: There were 57 “no CIN” patients, 23 histologically proven CIN 1 and 61 CIN2+ cases in the study population. CIN2+ was more often associated with DQA1*0401 (OR 6.68, 95% CI 1.47-30.29, p=0.014), DRB*15 (OR 2.99, 95% CI 1.22-7.39, p=0.017), DQB1*0401 (OR 2.91, 95%CI 1.11-7.68, p=0.03), DQA1*0103 (OR 2.72, 95% CI 1.02-7.21, p=0.045), DRB1*11 (OR 2.42, 95% CI 1.10-5.33, p=0.029) and DQB1*0301 (OR 1.94, 95% CI 1.12-3.38, p=0.018). Women with “no CIN” more often had DQB1*0501 (OR 0.17, 95% CI 0.04-0.81, p=0.026), DRB1*16 (OR 0.21, 95% CI 0.06-0.78, p=0.019), DQA1*0301 (OR 0.35, 95% CI 0.14-0.87, p=0.024) and DRB1*14 (OR 0.59, 95% CI 0.01-0.46, p=0.007).Conclusions: In the current study we have demonstrated a strong association with risk and protective HLA class II alleles that are determined by the HLA-DRB1*; DQA1*; DQB1*.
Hepatic splenosis: a report of a very rare case
Authors: Cristina Kampa Katia , AA Guerra Juliana Arrais , Paula Percicotte Ana , Zaparolli Maurício , Raeder Costa Marco Aurélio , José B Ramos Eduardo
Published: March 2024

Splenosis is a heterotopic autotransplantation of splenic tissue after abdominal trauma or surgical intervention. Hepatic splenosis is very rare and the diagnosis is challenging, being confused with other benign and malign nodular hepatic lesions. As it is usually asymptomatic, most diagnoses are incidental. Despite being a rare condition, splenosis should be considered in differential diagnosis with other nodular hepatic lesions and accurate diagnosis is important to avoid unnecessary invasive procedures. Here we describe a case of a patient that underwent splenectomy 20 years ago, due to abdominal trauma. The patient was asymptomatic, without alteration in physical exam. The hepatic nodule was found on routine examination. The initial suspicion was of hepatic adenoma and therefore the patient underwent hepatectomy, with good clinical evolution. The definitive diagnosis was obtained only with anatomopathological analysis, characterized by the presence of splenic tissue in the hepatic parenchyma. Splenosis is a benign condition, usually occurring after splenectomy, with implants of splenic tissue in other organs. The etiological differentiation of the nodules with the use of radiological and laboratory tests is difficult, and often the diagnosis is confirmed only after surgical procedure with anatomopathological study. The correct diagnostic definition is necessary and important because the differential diagnoses include hepatocellular carcinoma and other neoplasms, especially in patients with liver cirrhosis. Surgical treatment should be performed only if the diagnosis has not been defined or if there is complication due to the presence of splenic tissue in the affected organ.
Effectiveness of subarachnoid anesthesia with morphine as treatment of postoperative pain in cesarean section
Authors: Rodríguez Yuliel Varona , Manresa Liliam Maria Castle , Cut Ariane Sainz , Arias Julius Michel , White Loved
Published: March 2024

Foundation: The Postoperative pain is considered time-limited pain, often poorly controlled. Its management requires a great challenge, since postoperative analgesia must provide the mother with adequate control and at the same time facilitate care for the baby. Objective: To evaluate the effectiveness of postoperative analgesia with the use of intrathecal morphine. Method: Observational, descriptive and cross-sectional study carried out at the Martín Chang Puga General Teaching Hospital in the Nuevitas municipality, province of Camagüey, between January 2021 and December 2022. The sample was made up of 36 patients to whom subarachnoid anesthesia was applied with Hyperbaric lidocaine plus morphine for cesarean section. Results: The age between 27-31 years predominated, 63.9% of those who underwent cesarean section did not report postoperative pain. Almost half of the sample (47.2%) studied presented side effects with the use of intrathecal morphine, with pruritus predominating. 80.5% of patients were satisfied with postoperative analgesia. Conclusion: The majority of patients found satisfaction with the analgesic treatment despite the presence of adverse effects, so it can be stated that the use of intrathecal morphine is effective in the management of post-cesarean pain.
Elimination of paralogisms of thermodinamics
Authors: Etkin V.
Published: March 2024

A number of specific examples show that replacing the energy carrier of the thermal form of motion with entropy as a heat transfer coordinate leads to a number of paralogisms, the number of which increases as the scope of application of thermodynamics expands. The epistemological roots of these paralogisms are revealed and a more general measure of the amount of chaotic motion, called a thermal impulse for brevity, is proposed. It is shown how its use instead of entropy eliminates all paralogisms known and discovered by the author, including the prediction of the thermal death of the Universe and the degradation of biological systems. It is concluded that replacing entropy with a thermal impulse opens the way to expanding the capabilities of the thermodynamic method in the study of nonequilibrium systems and non-static processes, to the synthesis of thermodynamics with other fundamental disciplines and to a deeper understanding of the world order.
Закономірності впливу ізовалентних заміщень атомів на будову фаз на основі сполук типу AIILn2B2 IIIO7
Authors: Тітов Ю.О. , Слободяник М.С. , Чумак В.В.
Published: March 2024

На підставі аналізу структурних даних фаз (AII, AII*)(Ln, Ln*)2 B2 IIIO7 (AII = Ba, Sr, AII* = Sr, Ca, Ln = La, Nd, Ln* = Sm, Dy, BIII = In, Sc) визначено закономірності впливу ізовалентних заміщень атомів AII та Ln у шаруватій перовськітоподібній структурі сполук типу AIILn2B2 IIIO7 на її будову. Встановлено, що збільшення ступеня заміщення атомів AII та Ln у шаруватій структурі фаз AII1−x, AxII*Ln2 B2IIIO7 і AIILn2−x Lnx*B2 IIIO7 зумовлює зростання ступеня деформації (Δ) міжблокових поліедрів АО9 та зменшення довжини міжблокової відстані А—О. Величини ΔАО9 і ΔАО12 у структурі AII1−x, AxII*Ln2 B2 IIIO7 і AIILn2−x Lnx*B2IIIO7 залежать від типу сингонії ґратки і найвищі в тетрагональних твердих розчинах. Характер розподілу атомів Ba, Sr та рідкісноземельних елементів у структурі (AII, AII*)(Ln, Ln*)2 B2IIIO7 визначається величиною різниці їх радіусів. Її збільшення сприяє впорядкуванню розподілу атомів Ba, Sr та рідкісноземельних елементів по поліедрах АО9 і АО12. Виявлено структурні фактори, які впливають на стабільність фаз (AII, AII*)(Ln, Ln*)2 B2IIIO7 з шаруватою перовськітоподібною структурою.
Gestational Carrier Pregnancies: Legal and Ethical Considerations for Pediatricians
Authors: Wilcox Hayley M. , Cummings Christy L. , Pope Thaddeus M. , Mercurio Mark R.
Published: March 2024

This case explores the legal and ethical considerations for pediatricians surrounding gestational carrier pregnancies in the United States. Because of high success rates for assisted reproduction, state laws supporting same-sex adoption and surrogacy, and established legal precedents, gestational carrier pregnancies are increasingly common. The case presented involves a gestational carrier in preterm labor at 30 weeks’ gestation with malpositioned twins who declines a cesarean delivery. Three commentaries are presented. The first highlights the importance of understanding the ethical implications of gestational carrier pregnancies in prenatal counseling. The second commentary emphasizes the pregnant person’s right to autonomy and bodily integrity, and discusses considerations in surrogacy pregnancies, including the authority to authorize a cesarean delivery, valid informed consent, and decision-making for neonates. The third commentary discusses autonomy, emphasizing the importance of contracts in surrogacy pregnancies, and suggests that, in the case of a conflict between the gestational carrier and the intended parent(s), the gestational carrier’s preference should be decisive regarding medical care during pregnancy. These discussions highlight key concepts for ethically informed and family-centered care in gestational carrier pregnancies and deliveries.
Biogastronomica
Authors: Dalby Andrew
Published: March 2024

The article investigates the life Joseph Cooper, chief cook to King Charles I and author of The Art of Cookery Refin’d and Augmented (1654); see also the article by Louise Richardson and J.R. Isabell in PPC 18.
Devising an approach for the automated restoration of shipmaster’s navigational qualification parameters under risk conditions
Authors: Ponomaryova Victoria , Nosov Pavlo , Ben Andrii , Popovych Ihor , Prokopchuk Yurii , Mamenko Pavlo , Dudchenko Sergiy , Appazov Eduard , Sokol Ihor
Published: March 2024

The object of this study is the safety control system of ship management, by identifying and restoring the qualification parameters of shipmasters in critical situations.
The task solved in the study is the timely determination of an insufficient level of qualification for the performance of certain operations in controlling the movement of the ship, by applying a formal-logical model of detecting the intuitive actions of the operator-shipmaster and gradually restoring his/her qualification parameters using the devised method.
The stages of development and the formal-logical structure of the model and method in terms of cognitive automation were described in detail as the study results. It was possible to ensure early detection of risks when controlling the movement of the ship in 56 % of cases, during a laboratory experiment on simulators, which in 24 % of cases turned out to be particularly dangerous.
The interpretation of the results involved algorithmizing complex and formalized data on the actions of operators and the application of the method of restoring their qualification parameters, which allowed a comprehensive approach to safety management.
The distinguishing features of the findings were to predict the level of danger by simulating maritime operations with input navigational and individual conditions. This made it possible to improve the effectiveness of operations to 89 %, reduce the phenomenon of loss of control over the course to 32 %, reduce critical situations to 7 % and the cost of resources.
The scope and conditions of practical use involve a comprehensive assessment of external and internal influences on the level of danger, delay in decision-making by operators, as well as sailing conditions. The simulation results could be used to devise strategies for planning maneuvers, predicting risks, and developing maritime security systems
Design of ammonia sensor based on ZnO for analyzing hazards at critical infrastructure
Authors: Minska Natalia , Bas Oleh , Hvozd Viktor , Hryhorenko Oleksandr , Levterov Alexander , Maliarov Murat , Matiushenko Mykola , Tarasov Serhii , Chernysh Roman , Shevchenko Olga
Published: March 2024

A gas sensor based on ZnO has been designed, which demonstrates sensitivity to NH3 under standard conditions (temperature, 25 °С; pressure, 101.3 kPa). The experimental sample was manufactured by magnetron sputtering at direct current. A VUP-5M vacuum unit with an original material-saving magnetron was used to produce ZnO films. To analyze the efficiency of the gas sensor to ammonia (NH3) under standard conditions, its operating characteristics were studied. The concentration of NH3 for investigating operating characteristics was chosen at the level of 25 ppm. To determine the resistivity of the contacts of the instrument structure, the current-voltage characteristics of the gas sensor were examined in the voltage range between −100 and +100 V. Based on the results of investigating the current-voltage characteristics, which have a linear character, the resistivity of the contacts was confirmed. To study the sensitivity of the gas sensor to the target gas, the change in resistance of the sensitive layer of the gas sensor under the influence of NH3 with a concentration of 25 ppm under standard conditions was explored. The study results demonstrated the high sensitivity of the gas sensor to the target gas – at the level of 229 relative units. The investigation of the response and recovery time of the gas sensor showed that the ZnO-based gas sensor has a response and recovery time of 20 and 26 s, respectively. The selectivity of the ZnO-based gas sensor was studied. The selectivity study was carried out by determining the sensitivity of the gas sensor in the presence of vapors of various gases, namely methanol, ethanol, acetone. The study results showed that the reaction to ammonia is selective compared to the reaction to other gases. The results of examining the working characteristics of the ammonia gas sensor demonstrate the high efficiency of its application under standard conditions and a low concentration of the target gas
conDENSE: Conditional Density Estimation for Time Series Anomaly Detection
Authors: Moore Alex , Morelli Davide
Published: March 2024

In recent years deep learning methods, based on reconstruction errors, have facilitated huge improvements in unsupervised anomaly detection. These methods make the limiting assumption that the greater the distance between an observation and a prediction the lower the likelihood of that observation. In this paper we propose conDENSE, a novel anomaly detection algorithm, which does not use reconstruction errors but rather uses conditional density estimation in masked autoregressive flows. By directly estimating the likelihood of data, our model moves beyond approximating expected behaviour with a single point estimate, as is the case in reconstruction error models. We show how conditioning on a dense representation of the current trajectory, extracted from a variational autoencoder with a gated recurrent unit (GRU VAE), produces a model that is suitable for periodic datasets, while also improving performance on non-periodic datasets. Experiments on 31 time-series, including real-world anomaly detection benchmark datasets and synthetically generated data, show that the model can outperform state-of-the-art deep learning methods.
SHORT OVERVIEW AND HIGHLIGHTS OF THE HISTORY OF THE GERMAN GEL PROPULSION RESEARCH AND TECHNOLOGY DEVELOPMENT ACTIVITIES
Authors: Ciezki Helmut K. , Naumann Karl Wieland , Hürttlen Jürgen , Kurilov Maxim , Kirchberger Christoph , Weiser Volker , Schaller Uwe , Hopfe Norman , Caldas-Pinto Pedro , Ramsel Jürgen , Rest Sebastian F.
Published: March 2024

Gel mono- and bipropellants (i.e., gelled fuels and/or gelled oxidizers) are interesting candidates for
advanced low-hazard rocket or ramjet propulsion systems and gas dynamic systems. Gel propellants combine major advantages of solid propulsion systems and liquid propulsion systems, such as easy and simple storage and handling characteristics (solid systems) and excellent throttleability (liquid systems). This article gives a short overview of the themes and the obtained results about the work conducted in Germany within the last two and a half decades, whereas a focus is set on the progress achieved in the last years.
In Vitro Bioactivities and Characterization of Mycelial Extracts from Different Strains of Phellinus igniarius (Agaricomycetes)
Authors: Dong Yating , Zhao Jin , Miao Renyun , Feng Rencai , Wang Tao , Lin Junbin , Gan Bingcheng , Tan Xingyi , Wu Yiyou
Published: March 2024

To fully utilize Phellinus igniarius fermentation mycelia, the present study investigated the in vitro antioxidant and α-amylase inhibitory properties of four Ph. igniarius strains. Organic solvents were used to extract fatty acids, phenolics, and flavonoids from the selected mushrooms. The composition and bioactivity of the extracts were evaluated. The lipid yield obtained using petroleum ether (7.1%) was higher than that obtained using 1:1 n-hex-ane+methanol (5.5%) or 2:1 dichloromethane+methanol (3.3%). The composition and relative content of saturated and unsaturated fatty acids in the petroleum ether extract were higher than those in other solvent extracts. Furthermore, ethyl acetate extracts had higher flavonoid and phenolic content and better antioxidant activity than other extracts; however, the 70% ethanol extracts had the best α-amylase inhibitory activity. The supernatant from the ethanol precipitation of aqueous and 1% (NH4)2C2O4 extracts could also be biocompound sources. This comparative study is the first highlighting the in vitro antioxidant and α-amylase inhibitory properties of the four strains of Ph. igniarius extracts prepared using different organic solvents, which makes the investigated species and extracts promising for biological application.
Molecular Pathogenesis, Organ Metastasis, and Targeted Therapy for Non-Small-Cell Lung Cancer
Authors: Abdullah Salik , Chakraborty Ratul , Kumkar Pratiksha Somnath , Debnath Biplab , Bala Asis
Published: March 2024

Around 2 million people are diagnosed with lung cancer annually, causing 20,000 deaths. Non-small cell carcinomas account for 80-85% of lung cancer cases. Over the last few decades, there has been an improved understanding of the chromosomal makeup of lung cancer. As a result, the clinical care and treatment of patients with advanced or metastatic non-small-cell lung cancer (NSCLC) have changed. This is possible due to advanced molecular techniques and chromosomal analysis, which have revealed persistent genetic abnormalities. Specific medications have increased the median survival time for NSCLC patients. Pulmonary pathology and oncology patients now receive personalized medication based on genetic abnormalities and other prognostic indicators. However, the diagnosis algorithms become complicated due to the various testing methods available. Consensus standards and recommendations have standardized NSCLC diagnostic testing. This article discusses the molecular genetic landscape of NSCLC and the latest therapy developments, focusing on clinically relevant changes using several schematic and tabular representations.
A NOVEL MULTIMODAL BIOMETRIC SYSTEM BASED ON DEEP FUSION OF ECG AND EAR
Authors: Khalaf Mohamed S. , El-Zoghdy S. F. , Barsoum Mariana , Omara Ibrahim
Published: March 2024

Due to their unique and measurable properties, biometric security systems are more reliable and secure than traditional ones. However, unimodal biometric systems suffer from various problems such as spoof attacks, non-universality, intra-class variances, inter-class similarities, and noisy data. To overcome these problems, multimodal biometric systems which utilize more trait features have emerged to efficiently authenticate the identity of the individuals in various real-world applications. Along the same line, this paper proposes a multimodal biometric system for human recognition based on deep features fusion of electrocardiograms (ECG) signals and ear images. The proposed system is hard to spoof compared to current systems as the ear biometric provides a fixed structure over an acceptable period of human life, and the ECG offers the characteristic of the person's liveness. It also applies a transfer-learning methodology to extract discriminative deep features by exploiting a pre-trained VGG-m Net model. Furthermore, to improve the efficiency of the proposed modelâs training, augmentation techniques were utilized to further increase the size of the training data. A course of experiments has been conducted to assess the performance of the proposed approach for unimodal and multimodal biometric traits. The experimental results reveal that the proposed system achieves promising results and outperforms the unimodal of ECG and ear, and other state-of-the-art multimodal biometric systems.
ANTI-CORROSION COATING BASED ON PRODUCTION AND CONSUMPTION WASTE
Authors: Sergeev E.S. , Bogachuk D. V. , Filippova O.P. , Ladygina O.V.
Published: March 2024

The process of corrosive decay of metal products leads to serious consequences both for the products themselves and for the quality of the environment, therefore protection against corrosion is carried out by isolating structures from an aggressive environment using various protective coatings. One of the promising directions in the sphere of corrosion protection is the production of such coatings based on waste with anti-corrosion potential (galvanic sludge, used motor oil), which is thesubject of this article. On the basis of the analysis of chemical composition and physicochemi-cal characteristics of the considered wastes the possibility of their use for obtaining effective anti-corrosion coating is proved. The realization of the proposed technology makes it possible to solve a number of topical issues of important social and economic importance, namely the problem of the accumulation of hazardous waste and the preservation of the general metal stock.
FEATURES OF DEVELOPMENT OF BASHKORTOSTAN OIL FIELDS IN CARBONATE SEDIMENTS
Authors: Garifullin A.Sh.
Published: March 2024

The main oil reserves on the territory of Bashkortostan lie in terrigenous sediments. Intensive drilling and long development periods have led to the fact that oil reserves in terrigenous deposits have been significantly depleted. In the last decade, 80 % of the increase in reserves was provided by carbonate deposits. The share of remaining oil reserves in carbonate reservoirs has been steadily growing over the past 20 years and by the beginning of 2023 amounted to 32 %.The low efficiency of waterflooding of carbonate sediments and, at the same time, the achievement of high recovery factors with dense well patterns, characteristic of a water-pressure regime, are explained by the hypothesis put forward of the formation of vertical and inclined man-made cracks during the process of percussion-rotary drilling of wells.It is substantiated that when carrying out geological and hydrodynamic modeling it is necessary to take into account the presence of man-made cracks in vertical and inclined direc-tions and hydrodynamic connection through dense reservoirs with underlying water-saturated porous rocks. It is recommended to continue studying the influence of man-made fracturing in horizontal wells and in open-bottom wells on the technological indicators of the development of an oil facility.
PRACTICAL USE OF GAMIFICATION APPROACHES AND GAME-BASED SIMULATORS FOR OIL AND GAS FIELD DEVELOPMENT IN ADULT TRAINING
Authors: Mironenko A.A. , Sultanov A.R. , Fedorov Aleksey E. , Ibragimova L.D.
Published: March 2024

The article discusses gamification methods as a means of improving the effectiveness of training for professionals. There is described specific methods applicable to training, including a system of points and levels, assignments, awards and achievements, ratings and competitions. Practical experience of using the simulator of oil field development is given, which is used in internal education courses, practical classes as an interactive component, as well as a tool in the annual internal corporate competition. It is concluded that gamification can significantly improve the learning process, making it more engaging and stimulating. At the same time, the authors emphasize that, despite the positive practices of gamification, it is important to maintain a balance between gamification and traditional methods in order to ensure high learning effectiveness.
Una nueva y diminuta Matelea (Apocynaceae) de Veracruz, México
Authors: Alvarado-Cárdenas Leonardo O. , Díaz-Mota Sarahí , Pío-León Juan Fernando
Published: March 2024

Antecedentes: En el trabajo de campo realizado en el municipio de Altotonga, Veracruz, se localizaron poblaciones de una especie del género Matelea con flor sobresalientemente pequeña, que no coincidía con las especies reportadas para México, sino que es morfológicamente similar a M. anomala, especie endémica de Bolivia.

Preguntas: ¿las poblaciones de la Matelea de Altotonga corresponden a una especie nueva para la ciencia o a una distribución disjunta de M. anomala?

Especies de estudio: Matelea sp. nov.

Sitio y años de estudio: Reserva del Río Pancho Poza, Altotonga, Veracruz, México.

Métodos: Se realizó comparación morfológica con las especies mexicanas de Matelea y con M. anomala, empleando el concepto cohesivo de especie.

Resultados: Se describe a Matelea lilliputiana como especie nueva para la ciencia, endémica del municipio de Altotonga, Veracruz. Se diferencia de M. anomala por presentar una corona ginostegial 5-lobada con ápices bifurcados (vs. corona no claramente lobada y márgenes fimbriados en M. anomala), estípite anguloso (vs. cilíndrico) y cáliz densamente pubescente-hirsuto (vs. glabrescente). Adicionalmente, M. lilliputiana es endémica de México y crece en bosque de pino-encino con elementos de mesófilo, mientras que M. anomala es endémica de Bolivia y crece en matorral estacionalmente seco.

Conclusiones: Con el presente descubrimiento, el estado de Veracruz alcanza 126 especies de Apocynaceae, con cinco endémicas. A nivel mundial, es la segunda especie del género en presentar corolas menores a 5 mm de largo y la primera para México.
Comparison of the microbiome and mycobiome in tissues of the tropical carnivorous epiphytic herb Utricularia jamesoniana Oliv. (Lentibulariaceae)
Authors: Naranjo-Aguilar Valeria , Mora-Castro Rebeca , Morera-Huertas Jessica , Acuña-Castillo Rafael H. , Rojas-Jimenez Keilor
Published: March 2024

Background: Utricularia jamesoniana, a small epiphytic plant found in wet tropical forests, stands out for its carnivorous habit, intricate trap system, and small but beautiful and complex flowers. This species remains relatively understudied despite its wide geographical distribution and curious adaptations.

Questions: Our aim is to elucidate the composition of bacterial and fungal communities inhabiting both the bladders and leaves of Utricularia jamesoniana, facilitating the comprehension of the physiology and ecological dynamics of this carnivorous species.

Methods: In this study, we employed 16S rRNA and ITS sequencing to compare the prokaryotic and fungal communities within leaves and traps of U. jamesoniana.

Results: The analysis of amplicon sequence variants (ASVs) unveiled notable differences in community composition depending on the plant tissue and type of microorganism. Prokaryotic communities predominantly comprised Proteobacteria and Actinobacteriota, featuring genera such as Acidocella, Bradyrhizobium, Ferritrophicum, and Ferrovum. Fungal communities were dominated by Ascomycota and Basidiomycota, encompassing representatives of Dothideomycetes, Sordariomycetes, Eurotiomycetes, and Agaricomycetes, as well as ASVs related to Mycosphaerellaceae, Colletotrichum, Aspergillus, and Thanatephorus. We determined that the prokaryotic diversity was higher in the bladders with respect to the leaves. Fungal communities, in turn, were more diverse in leaves than in bladders.

Conclusions: This study sheds light on the microbial communities associated with this carnivorous epiphyte and provides valuable insights into the intricate relationships between the plant and its microbial inhabitants across different tissues.
Lean construction: Implementing the Last Planner System on mining projects
Authors: Govindasamy T. , Bekker M.C.
Published: March 2024

The potential benefits of implementing the Last Planner System (LPS) on mining infrastructure projects were explored through two case studies in the South African mining industry. The first part of the study involved measurement of the impact of LPS through earned value techniques on secondary project data. The second part sought to establish the lean construction success factors leading to improvements in construction performance. This was done by means of a research questionnaire distributed to the project owner's teams, contracted parties, and the LPS facilitators. The results revealed a positive correlation between LPS application and planned percentage complete. However, the performance achieved during the LPS pilot was not sustained. The success factors and benefits considered most evident in the case study pilot differed among the three stakeholder groups. The findings are expected to guide construction stakeholders to better define performance measures and focus on factors required to make LPS implementation more effective in the South African mining sector.
СПЕЦИФИКА РЕАЛИЗАЦИИ ИДЕИ РАВЕНСТВА ВОЗМОЖНОСТЕЙ КАК ВОПЛОЩЕНИЯ СОЦИАЛЬНОГО ЭГАЛИТАРИЗМА В ЖИЗНЕННЫХ СТРАТЕГИЯХ РОССИЙСКОЙ МОЛОДЕЖИ
Authors: Некрасов Евгений Евгеньевич
Published: March 2024

Целью исследования является объективная необходимость осмысления эгалитарных оснований жизненных способностей молодежи, интегрирующих социальную статику и динамику.

Методы исследования составили структурно-функциональный подход, неоинституциональный подход, концепция социокультурной саморегуляции жизнедеятельности молодежи, позволяющая выделить важные ориентиры в изучении поведенческих установок и практик молодежи в контексте развития эгалитарных оснований жизненных стратегий молодежи.

Результаты. Идея равенства возможностей в жизненных стратегиях российской молодежи рассматривается как модель поведения, сформированная в результате взаимодействия объективных (социально-статусных) и субъектных (мотивационных) установок молодых людей, связанных с их представлением о своем месте в обществе, жизненными планами, самопроектированием и самоопределением в молодежной среде. Влияние эгалитаризма на жизненные стратегии молодежи выражается в различных вариантах трансформации жизненных планов. Часто молодые люди выбирают в качестве целей жизненных стратегий повышение личной значимости (высокий уровень потребления, успешная карьера, семейное благополучие). В этом случает способы реализации жизненных целей носят прикладной и инструментальный характер.

Перспективы использования результатов. Результаты исследования могут быть полезны для дальнейшего исследования жизненных стратегий российской молодежи.
212Gbps high-power EML for 800G artificial intelligence optical transmissions
Authors: Jack Jia-Sheng Huang , Hsiang Szu Chang , Yi-Ching Hsu , Alex Chiu , ZiHan Fang , Chun-Yen Yu , Sam Hsiang
Published: March 2024

We present a high-power, high-speed 212Gbps four-level Pulse Amplitude Modulation (PAM4) Electro-absorption Modulated Laser (EML) designed for 800G LR4 optical transmission and Artificial Intelligence (AI) applications. The Lan wavelength division multiplexing (LWDM) EML channels, operating at wavelengths of 1295.56 nm, 1300.05 nm, 1304.58 nm, and 1309.14 nm in 800G LR4 optical transceivers, exhibit clear eye openings even after 10km of transmission. Our 212Gbps PAM4 LWDM EMLs demonstrate high bandwidth, high extinction ratio, high power, and high energy efficiency, making them suitable for 10km transmission and environmentally friendly connectivity.
KASP genotyping v2
Authors: Kroll Francois , not provided FishFloorUCL
Published: March 2024

KASP is a genotyping assay which you can use to differentiate wild types vs heterozygous vs homozygous larvae/finclips. It is well suited to genotype a SNP or a small CRISPR-generated indel. Once you confirmed it is working well, the assay is pretty fast to run so you may want to use KASP if you will routinely genotype tens of samples.
Transforming pJC8 into HB101 v1
Authors: Evans Bonnie
Published: March 2024

Taken from Mix and Go E. coli Transformation Kit (see attachment). Transforming E. coli HB101 with pJC8-empty cosmid to use as a control strain.
Penentuan Lintasan Terpendek Perjalanan Pengiriman Barang Menggunakan Algoritma Cheapest Insertion Heuristic (Studi Kasus PT. Indah Logistik Cargo Bandar Lampung)
Authors: Ananda Ahya Shofa , Notiragayu Notiragayu , Wamiliana Wamiliana , Ansori Muslim
Published: March 2024

The growth in the number of online shop members has caused the value of e-commerce transactions in Indonesia to increase. This resulted in increased distribution of goods at PT. Indah Logistik Cargo. One of the constraints at PT. Indah Logistik Cargo is inefficient routes the distribution of packages. Distribution problem at this delivery service company include the Traveling Salesman Problem (TSP), which can be solved using the Cheapest Insertion Heuristic (CIH) algorithm. In this paper, the solution is carried out manually and also utilizes the Python programming language to optimize the delivery service travel path. Factual data owned by PT. Indah Logistik Cargo states that the total distance for delivering goods is 51.600 meters. Meanwhile, based on the results of manual calculations using the CIH algorithm, a total distance of 51.550 meters was obtained, which is smaller by a difference of 50 meters from the factual data. Furthermore, the results of calculations using the Python programming obtained 47.150 meters, or a difference of 4.450 meters. Therefore, the use of the CIH algorithm is proven to provide a path with a smaller total distance traveled.Keywords: CIH Algorithm, Goods Delivery, Shortest Path.AbstrakPeningkatan jumlah anggota online shop membuat nilai transaksi e-commerce di Indonesia mengalami kenaikan. Hal ini mengakibatkan meningkatnya pendistribusian barang pada PT. Indah Logistik Cargo. Kendala pada PT. Indah Logistik Cargo adalah keterlambatan penyaluran paket ke para konsumen akibat jalur lintasan yang tidak efisien. Permasalahan pendistribusian pada perusahaan jasa pengiriman ini termasuk permasalahan Travelling Salesman Problem (TSP) yang dapat diselesaikan menggunakan Algoritma Cheapest Insertion Heuristic (CIH). Pada tulisan ini, penyelesaian masalah tersebut dilakukan secara manual dan juga menggunakan bahasa pemrograman Python. Data faktual yang dimiliki PT. Indah Logistik Cargo bahwa total jarak pengiriman barang yaitu 51.600 meter. Sementara, berdasarkan hasil perhitungan dengan algoritma CIH secara manual diperoleh total jarak 51.550 meter, yang lebih kecil dengan selisih 50 meter dari data faktual. Sedangkan, hasil perhitungan dengan bahasa pemrograman Python diperoleh 47.150 meter, atau mempunyai selisih 4.450 meter. Oleh karena itu, penggunaan algoritma CIH terbukti memberikan lintasan dengan total jarak tempuh yang lebih kecil.
ANALISIS INVESTASI PERUMAHAN PURI MAHKOTA MUKTIWARI DI KABUPATEN BEKASI
Authors: ALDI ALDI , Yustiarini Dewi , Nurasiyah Siti
Published: March 2024

As the population grows rapidly and the standard of living increases, the demand for housing will increase. One way to meet housing needs is to build housing. Housing development must be in accordance with careful planning in determining the investment model to be made in housing development. The initial stages of housing development start from surveying the location, number and type of houses to be built, marketing, to selling to consumers. The housing development process must also be calculated economically with the investment method, to find out whether this housing can be economically profitable or not. Based on the calculation of investment analysis with an investment period of 6 years, the Net Present Value (NPV) is Rp. 33,716,228,908 (NPV0), the Internal Rate of Return (IRR) is 23,18% (IRRMARR), Payback Period (PP) in the 3rd year to 11th months is smaller than the 6 year investment period, Benefit Cost Ratio (BCR) is 1.42 (BCR 1), and Break Event Point (BEP) gets a percentage for type 30/60 of 90% with 132 units, type 36/60 by 69% with 207 units, type 36/72 by 56% with 172 units, and type 48/84 by 48% with 32 units. And from the sensitivity analysis results it is known that housing investment Puri Mahkota Muktiwari will still be feasible if the increase in investment costs is less than 20.15%, the decrease in the occupancy rate is not more than 16.74%, the decrease in the selling price level is not more than 16.7% and the increase in loan interest rates is less of 122.22%.Keywords: Investment Feasibility,Housing, industrial estate, Investment analysis, Sensitivity Analys
ANALISIS TINGKAT KESELAMATAN LALU LINTAS PERSIMPANGAN TAK BERSINYAL DENGAN METODE TRAFFICT CONFLICT TECHNIQUE (TCT) PADA PEREMPATAN DUREN, TANGERANG SELATAN, BANTEN
Authors: Labbaik Muhammmad Daffa Naufal
Published: March 2024

This study was carried out at the Duren Intersection, which connects Jl. Jl. Menjangan Raya Jl. Merpati Raya Jl. Cendrawasih Raya The goal of Ki Hajar Dewantara is to examine: 1) the level of safety of unsignalized intersections by paying attention to the degree of traffic movement-related conflict; 2) the volume of vehicles at the Duren Quarter during off-peak hours; 3) the elements that contribute to accidents. The Traffic Conflict Technique (TCT) is used to analyze the data by putting oneself in a location with a high risk of accidents.The consequences of the review are as per the following: (1) There are 17 conflicts that happen with a typical chance to mishap of around 0.24 seconds. Street clients who are many times associated with clashes, to be specific motorbikes, by slowing down or dialing back the vehicle. (2) During the off top hour, the biggest number of crossing points happened on Sundays, around 5581 vehicles and loosened up on Fridays, around 4277 vehicles. (3) the variables bringing about the principal mishap, in particular the human component that didn't focus on the circumstance while going through the convergence and the second, street and natural elements, to be specific the presence of a huge contrast in street width on one arm. This causes a lopsidedness toward traffic at Duren Crossroads, bringing about a limited scale gridlock on one of the arms of the Duren crossing point.Keywords: Safety Level, Mishap factor, Traffic Conflict Technique (TCT), Unsignalized intersection, Vehicle Volum