bluuebunny/crossref_metadata_2025 huggingface dataset:
Tinjauan Atas Strategi Komunikasi Pemasaran Melalui Media Sosial Instagram Pada Dinas Perdagangan Dan Perindustrian Kota Bogor
Authors: Rosadi Reysi Resmidianti , Mulyana Mumuh
Published: September 2023

Economic growth is an important indicator of the success of national development. In terms of national economic growth, small and medium industries (IKM), which are also part of micro, small and medium enterprises (MSMEs), are considered capable of playing an important role in driving economic growth. The use of social media is spreading faster than ever before. One of the goals of social media is in the application of marketing communications. To advance the products of Small and Medium Industries in the City of Bogor, of course, cannot be separated from the role of more attractive and dynamic marketing communications.The research objectives are: 1) To find out the marketing communication strategy for small and medium industrial products through Instagram social media at the Bogor City Trade and Industry Service; 2) To find out the obstacles in implementing the marketing communication strategy for small and medium industry products through Instagram social media at the Bogor City Trade and Industry Service; 3) To find out efforts to deal with obstacles in implementing marketing communication strategies for small and medium industrial products through Instagram social media at the Bogor City Trade and Industry Service.The results of the study show that: 1) Social Media, Instagram is very well managed by the Department of Trade and Industry in providing information and interesting content from Small and Medium Industry products in the city of Bogor; 2) The obstacle faced is the difficulty of increasing insight to reach Instagram users outside of the Instagram account followers of the Bogor City Trade and Industry Service; 3) As for efforts to deal with obstacles, namely trying to publish content related to Small and Medium Industry products more often and to be accurate in providing information related to these IKM products.Keywords: Marketing Communication, Social Media Instagram, IKM
Pengaruh Sistem Informasi Akuntansi Dan Pengendalian Internal Terhadap Kualitas Laporan Keuangan Pemerintah Daerah
Authors: Bale Priscilla Julitha , Marlina Tri , Muanas Muanas
Published: September 2023

Financial reports are considered qualified if they are relevant, comparable, understandable and reliable. With the existence of an accounting information system, of course it will help effectiveness, relevance, efficiency and can make a report accurate. An accounting information system that does not use an internal control system is likely to have little benefit. The purpose of establishing an internal control system is to provide reliable and reliable financial reports. This study aims to examine the effect of accounting information systems and internal control systems on the quality of local government financial reports. The population in this study is the local government of Kupang City. The sample for this study used a non-probability sampling technique obtained from the finance department at 23 official offices in Kupang City. There are 69 respondents in this study. Data was collected by distributing questionnaires directly to 23 offices in Kupang City. The data analysis technique used is multiple regression analysis, partial test (t), and simultaneous test (f) using SPSS 29. The results of this study state that the Accounting Information System has no effect on the Quality of Financial Statements, the Internal Control System has an effect on the Quality of the Financial Reports of the Regional Government of Kupang CityKeywords: Accounting Information System, Internal Control System, Report Quality, Quality of the Financial Reports of the Regional Government of Kupang City
El Discurso Hegemónico y Contrahegemónico en la Práctica Docente Latinoamericana: Revisión Sistemática
Authors: Muñoz Blanco Leidy Carolina
Published: September 2023

Este artículo tiene como objetivo determinar cómo se presenta el discurso hegemónico y contrahegemónico en la práctica docente Latinoamericana. La modalidad del estudio corresponde a un artículo de revisión, por lo que se aplican técnicas de revisión documental y análisis bibliométrico, de lo cual se realizan apreciaciones cualitativas y cuantitativas de la información. En los resultados se describe la producción científica obtenida aplicando unos criterios de búsqueda para 10 años de antigüedad y tomando artículos de investigación que hayan abordado el tema en los países de América Latina. Asimismo, se determinan los principales autores, países y temas que se analizan en el discurso de los docentes. Por último, se identifican las principales tendencias de investigación que se han adelantado hasta la fecha y se establecen unas líneas de profundización que pueden guiar otros estudios en temas como los factores pedagógicos asociados a contextos específicos y a las expectativas de formación profesional.
“VOLLEYBALL IS A GAME THAT IS SLOWLY REPLACING FOOTBALL”. FORMATION OF UKRAINIAN VOLLEYBALL TERMINOLOGY IN THE INTERWAR PERIOD IN GALICIA
Authors: Protsyk Iryna
Published: September 2023

In the interwar period, the active creation of Ukrainian volleyball terminology took place, the main principle of which in Galicia was the selection of specific equivalents for foreign names or the formation of neologism terms from the resources of the Ukrainian language. Stepan Haiduchok in the textbook “Vidbyvanka [Volleyball]ˮ presented the attempts of the people of Galicia to create a national term system of volleyball with a minimal share of borrowed terms.
In all groups of volleyball terminology analyzed in this article, actually Ukrainian names prevail. There are no foreign language terms among the nominations from the thematic groups – the names of the regulations (pravyla / prypysy hry), names of the match, its parts and results of the match (zmahannia, stricha, hraika, pivhraika, vyhrana, tochka), team name (druzhyna, muzheska / zhinocha / khlopiacha druzhyna, protyvna druzhyna, protyvnyk, pobidna / pobidzhena druzhyna), names of the playground, its parts and markings (hryshche, pole, vlasne / protyvne pole, muzheske / zhinoche hryshche, polovyna hryshcha, pole podavachiv / pryimachiv, linii hryshcha, bichna liniia, pobochyna, cholova liniia / hranytsia, seredynna liniia, seredynna, pravyi / livyi kut hryshcha, mistse podachi), inventory names (pryladdia, stoiak, stovp, stovpchyk, sitka, miach), names of equipment (sorochka, shtantsiata, kaptsi), names of actions of players in volleyball (hraty pivhraiku, hraty v linii napadu / pomochi, vyhraty, prohraty, vidbyvaty miach livoiu / pravoiu rukoiu / kulakom / doloneiu, pidbyvaty miach kulakom / oboma rukamy / ponad sitku, vdariaty miach zverkha / do protyvnyka, vybyty miach poza hryshche / na protyvne pole, perebyty miach na chuzhe pole, pidbyty miach dva razy pidriad, dobyvaty miach do svoioho napadu).
Several foreign language borrowings were recorded in thematic groups: the name of the game – volley-ball, the name of the participants in a volleyball match – trener (among the rest of the specific nominations of this group – hrach, napadach, pomichnyk, podavach, pryimach, spivhrach, zapasnyk, providnyk, suddia) and as part of hybrid terms individualna hra, reprezentatsiina druzhyna, rukhankova salia.
So, the volleyball terminology analyzed in the article has a distinctly national character: it is dominated by Ukrainian proper names and the share of loans is insignificant.
SEMANTIC-SYNTACTIC EXPLICATION OF THE VALENCE POTENTIAL OF THE VERB- TERMS АКОМПАНУВАТИ AND ДИРИГУВАТИ
Authors: Stashkiv Solomiia
Published: September 2023

The article examines the valence potential of verb-terms акомпанувати and диригувати. The three-component nature of their  valence framework was substantiated, and the main lexical-semantic groups of words that explain all non-predicate arguments were
defined. Typical morphological variants of addressee, object, and instrumental arguments were also established.
It was found that the verb акомпанувати generates three non-predicate valenceconditioned components: the subject of the action (the  person who performs the accompaniment), the addressee of the action (a musician or group of musicians who are accompanied), the  instrument of action (actually a musical instrument on which a melody is performed for accompaniment). The subject component dependent  on the verb акомпанувати is expressed by the names of persons (proper and common) either quantified or unquantified
sets of persons who accompany. The instrumental component, which is determined by the verb акомпанувати, is most consistently realized  by the names of musical instruments. It was emphasized that the verb акомпанувати is intransitive, therefore it can’t determine
the object component, despite its synonymy with the transitive verb супроводжувати (orchestra, choir, etc.).
The trivalency of the verb-term диригувати has been established. The non-predicate components of the subject of the action (the person  who conducts), of the object of the action (a piece of music that is conducted), and of the instrument of the action (an instrument
used to conduct) in its valence environment. Among all the components that cause the verb диригувати, the object of action has the broadest  lexical-semantic content, represented by proper and general names of musical groups, works, and their fragments.
A conclusion was made about the semi-obligatory usage of the instrument of the action with the verb акомпанувати and the optional usage  with the verb диригувати, the difference in its lexical-semantic expression was noted. The instrumental component, which is determined by  the verb акомпанувати, is most consistently implemented by the names of musical instruments; in the verb диригувати it is lexically limited  by the nouns hand and stick.
Constraining Cosmological Parameters Using the Cluster Mass–Richness Relation
Authors: Abdullah Mohamed H. , Wilson Gillian , Klypin Anatoly , Ishiyama Tomoaki
Published: September 2023

The cluster mass–richness relation (MRR) is an observationally efficient and potentially powerful cosmological tool for constraining the matter density Ωm and the amplitude of fluctuations σ
8 using the cluster abundance technique. We derive the MRR relation using GalWCat19, a publicly available galaxy cluster catalog we created from the Sloan Digital Sky Survey-DR13 spectroscopic data set. In the MRR, cluster mass scales with richness as

log

M

200

=
α
+
β
log

N

200

. We find that the MRR we derive is consistent with both the IllustrisTNG and mini-Uchuu cosmological numerical simulations, with a slope of β ≈ 1. We use the MRR we derived to estimate cluster masses from the GalWCat19 catalog, which we then use to set constraints on Ωm and σ
8. Utilizing the all-member MRR, we obtain constraints of Ωm =

0.31

−
0.03

+
0.04

and σ
8 =

0.82

−
0.04

+
0.05

, and utilizing the red member MRR only, we obtain Ωm =

0.31

−
0.03

+
0.04

and σ
8 =

0.81

−
0.04

+
0.05

. Our constraints on Ωm and σ
8 are consistent and very competitive with the Planck 2018 results.
The Effect of Self-Esteem on Loneliness in Individuals With Schizophrenia
Authors: Üşenmez Tülay Yıldırım , Budak Funda Kavak , Ayhan Mehmet Osman
Published: September 2023

The aim of this study was to evaluate the effect of self-esteem on loneliness in persons with schizophrenia. This study was conducted between August 2020 and August 2021 at a community mental health center affiliated with a research and training hospital in Turkey. This was a cross-sectional study that included 100 individuals with schizophrenia. A Descriptive Characteristics Form (DCF), the Rosenberg Self-Esteem Scale (RSES), and the University of California Los Angeles Loneliness Scale (UCLA-LS) were used for data collection. The individuals' total mean scores were 2.47 ± 1.24 for RSES and 56.42 ± 10.00 for UCLA-LS. A moderate negative correlation was found between these scores (
r
= −0.526,
P
< 0.01). The results revealed that the persons with schizophrenia had a moderate level of self-esteem and a high level of loneliness, possibly indicating that as self-esteem increases, loneliness levels may decrease.

[
Psychiatr Ann
. 2023;53(9):419–424.]
On some properties of a generalized min matrix
Authors: Polatlı Emrah
Published: September 2023

In this paper, we investigate a min matrix and obtain its $ LU $-decomposition, determinant, permanent, inverse, and norm properties. In addition, we obtain a recurrence relation provided by the characteristic polynomial of this matrix. Finally, we present an example to illustrate the results obtained.
Extension of probability models of the risk of infections by human enteric viruses
Authors: Masciopinto Costantino
Published: September 2023

This study presents a novel approach for obtaining reliable models and coefficients to estimate the probability of infection caused by common human enteric viruses. The aim is to provide guidance for public health policies in disease prevention and control, by reducing uncertainty and management costs in health risk assessments. Conventional dose-response (DR) models, based on the theory elaborated by Furumoto and Mickey [1], exhibit limitations stemming from the heterogeneity of individual host susceptibilities to infection resulting from ingesting aggregate viruses. Moreover, the scarcity of well-designed viral challenge experiments contributes to significant uncertainty in these DR models. To address these issues, we conducted a review of infection models used in health risk analysis, focusing on Norovirus (NoV) GI.1, pooled Enterovirus group (EV), Poliovirus 1/SM, and Echo-12 virus via contaminated water or food. Using a mechanistic approach, we reevaluated the known DR models and coefficients for the probability of individual host infection in the mentioned viruses based on dose-infection challenge experiments. Specifically, we sought to establish a relationship between the minimum infectious dose (ID) and the ID having a 50% probability of initiating host infection in the same challenge experiment. Furthermore, we developed a new formula to estimate the degree of aggregation of GI.1 NoV at the mean infectious dose. The proposed models, based on "exact" beta-Poisson DR models, effectively predicted infection probabilities from ingestion of both disaggregated and aggregate NoV GI.1. Through a numerical evaluation, we compared the results with the maximum likelihood estimation (MLE) probability obtained from a controlled challenge trial with the NoV GI.1 virus described in the literature, demonstrating the accuracy of our approach. By addressing the indetermination of the unmeasured degree of NoV aggregation in each single infectious dose, our models reduce overestimations and uncertainties in microbial risk assessments. This improvement enhances the management of health risks associated with enteric virus infections.
Interdisciplinary Application of Machine Learning, Data Science, and Python for Cricket Analytics
Authors: Imdad Haseeb , Ahmad Haseeb
Published: September 2023

The chapter explores the use of machine learning, data science, and Python in the context of cricket analytics. It highlights the importance of interdisciplinary collaboration and its potential to enhance the accuracy and speed of cricket analytics. It discusses the various data sources that can be used for cricket analytics and how machine learning algorithms can extract valuable insights. The chapter also provides an overview of various Python libraries commonly used in cricket analytics and explains how they can be used for data cleaning, feature engineering, and model building. Additionally, the chapter discusses the challenges and limitations of cricket analytics and provides suggestions for future research directions.
Naive Bayes Classification for Email Spam Detection
Authors: Syed Zain , Taher Omar
Published: September 2023

Email is one of the cheapest forms of communication that every internet user utilizes, from individuals to businesses. Because of its simplicity and wide availability, it is vulnerable to threats by perpetrators through spam with malicious intents, known to have resulted in huge financial losses and threatened the privacy of millions of individuals. Not all spam emails are malicious; however, they are a nuisance to users regardless. Because of these reasons, there is a dire need for good spam detection systems that are automatically able to identify emails as spam. This chapter aims to do exactly that by proposing a Naïve Bayes approach to create a spam detection system by using a combination of the Enron Email dataset and the 419 fraud dataset. The datasets are lemmatized in order to boost performance in terms of execution time and accuracy. Grid search is one technique adopted to maximize accuracy. Finally, the model is evaluated through various metrics and a comparative analysis is performed.
Energy Diversification in Africa
Authors: Akrofi Mark M. , Rabehi Ilhem N. , Abonyi Donald C. , Damascene Niyonzima J. , Ohunakin Olayinka S.
Published: September 2023

In this chapter, the authors establish and analyze the status of energy diversification in Africa from the year 2000 to 2017. Using the energy mix concentration index method, energy diversification indices were developed for 53 countries and territories for which data were available from the African Union Energy Commission's database. The researchers find that the electricity generation mix in Africa has moderately diversified between 2000 and 2017. While many countries have introduced renewable energy sources into their generation mix, the share of energy from these sources remains low compared to their fossil counterparts. More investment in renewable energy is essential to engender energy diversification, improve energy security, and foster clean energy transitions on the continent.
Staphylococcus aureus Enterotoxin B Is a Cofactor of Food Allergy beyond a Superantigen
Authors: Yuan Jin , Tong Ping , Wang Zhongliang , Xu Xiaoqian , Zhao Xiaoli , Meng Xuanyi , Wu Yong , Li Xin , Gao Jinyan , Chen Hongbing
Published: September 2023

Staphylococcus aureus enterotoxin B (SEB), one of the most common bacterial toxins in food contamination, has been poorly understood in relationship to food allergy outcomes. To investigate whether the ingestion of enterotoxins in food allergens could affect the development of food allergy, OVA-sensitized female BALB/c mice were challenged with OVA added with different doses of SEB or LPS. Allergic symptoms, such as diarrhea rate and hypothermia, could be aggravated in mice challenged with OVA and a low dose of SEB. The increased differentiation of Th2 and reduced expression of CD103 in dendritic cells was found in mice coexposed to SEB and OVA. Additionally, there was an increasing differentiation of Th1 induced by a high dose of SEB. The expression of ST2+ in intestinal mast cells was also increased in mice sensitized with a low dose of SEB and OVA. Employing several in vitro cell culture models showed that the secretion of IL-33 from intestinal epithelial cells and IL-4 from group 2 innate lymphoid cells, activation of bone marrow–derived dendritic cells, and differentiation of naive T cells were induced by SEB and OVA. Our work proved that challenge with low-dose SEB and OVA partly aggravated the food allergy, suggesting a (to our knowledge) new finding of the potential cofactor of food allergy and that the contamination of SEB in food allergens deserves attention for allergic and normal individuals.
Discoid lupus erythematosus associated with chronic granulomatous disease
Authors: De Almeida Figueiredo Ana Carolina , Matos Ana Luísa , Calvão Joana , Cardoso José Carlos
Published: September 2023

To the Editor, Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder in which a reduced activity of nicotinamide dinucleotide phosphate (NAPDH) oxidase leads to defective reactive oxygen intermediates (ROS) and impairs intracellular killing of microorganisms. Patients have recurrent bacterial and fungal infections as well as granuloma formations, and have a higher risk of autoimmune and inflammatory disorders like lupus erythematosus.1 A 20-year-old caucasian male with a diagnosis of autosomal recessive CGD was referred to our hospital because of a pruritic photosensitive rash on the face and hands, present for more than a year. [...]
Spatial association between socio-economic health service factors and sepsis mortality in Thailand
Authors: Sansuk Juree , Laohasiriwong Wongsa , Sornlorm Kittipong
Published: September 2023

Sepsis is a significant global health issue causing organ failure and high mortality. The number of sepsis cases has recently increased in Thailand making it crucial to comprehend the factors behind these infections. This study focuses on exploring the spatial autocorrelation between socio-economic factors and health service factors on the one hand and sepsis mortality on the other. We applied global Moran’s I, local indicators of spatial association (LISA) and spatial regression to examine the relationship between these variables. Based on univariate Moran’s I scatter plots, sepsis mortality in all 77 provinces in Thailand were shown to exhibit a positive spatial autocorrelation that reached a significant value (0.311). The hotspots/ high-high (HH) clusters of sepsis mortality were mostly located in the central region of the country, while the coldspots/low-low (LL) clusters were observed in the north-eastern region. Bivariate Moran’s I indicated a spatial autocorrelation between various factors and sepsis mortality, while the LISA analysis revealed 7 HH clusters and 5 LL clusters associated with population density. Additionally, there were 6 HH and 4 LL clusters in areas with the lowest average temperature, 4 HH and 2 LL clusters in areas with the highest average temperature, 8 HH and 5 LL clusters associated with night-time light and 6 HH and 5 LL clusters associated with pharmacy density. The spatial regression models conducted in this study determined that the spatial error model (SEM) provided the best fit, while the parameter estimation results revealed that several factors, including population density, average lowest and highest temperature, night-time light and pharmacy density, were positively correlated with sepsis mortality. The coefficient of determination (R2) indicated that the SEM model explained 56.4% of the variation in sepsis mortality. Furthermore, based on the Akaike Information Index (AIC), the SEM model slightly outperformed the spatial lag model (SLM) with an AIC value of 518.1 compared to 520.
A review on management of antiphospholipid syndrome in clinical practice
Authors: Siniscalchi Carmine , Rossetti Pietro , Carolla Gaetano , Di Micco Pierpaolo , Stella Adriano , Riva Michele
Published: September 2023

Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombotic or obstetric events occurring in patients with persistent antiphospholipid antibodies. Thrombotic APS is characterized by venous, arterial, or microvascular thrombosis. The diagnosis is accepted when both one clinical and one laboratory criteria according to the updated Sapporo classification are established. APS may occur in combination with other autoimmune diseases, mainly systemic lupus erythematosus, or in its primary form. Long-term anticoagulation with a vitamin K antagonist is the standard of care for patients who develop thrombosis, considering the high rate of recurrent thrombosis. The current international guidelines are not in favor of recommending direct oral anticoagulants for secondary prevention of thrombotic antiphospholipid syndrome, especially in the context of arterial thrombosis and triple-positive antiphospholipid patients. The most common approach, endorsed by the American College of Chest Physicians guidelines is the combination of heparin and low-dose aspirin (75-100 mg) daily for women who fulfill the clinical and serologic criteria for obstetric APS. New potential therapeutic approaches are under evaluation but actually the anticoagulation remains the cornerstone of treatment.
Family long QT syndrome type 2 associated with KCNH2 gene mutation: aborted sudden cardiac death
Authors: Elizalde Uribe Iván Alejandro , Mendoza Lagos Diego , Cazares Diazleal Aldo César , Andrade Cuellar Elias Noel , Payró Ramírez Gerardo
Published: September 2023

A complete screening was performed in a family after one of its members presented with a sudden cardiac death event. A genetical analysis revealed a mutation which led to a long QT syndrome.
Healthcare-associated Staphylococcus aureus infections in children in Turkey: A six-year retrospective, single-center study
Authors: Yakut Nurhayat , Ergenc Zeynep , Tuncay Sevgi Aslan , Bayraktar Sezin , Sayin Elvan , Ilki Arzu , Kepenekli Eda
Published: September 2023

Objective:

To describe clinical and epidemiological characteristics, antimicrobial susceptibility and mortality-associated factors of healthcare-associated infections (HCAIs) caused by Staphylococcus
(S.) aureus in children.

Methods:

We conducted a retrospective, single-centre study of pediatric HCAIs caused by S. aureus from a tertiary care hospital in Turkey between February 2014 and December 2019. The clinical and epidemiological characteristics and antimicrobial susceptibility of the methicillin-susceptible and methicillin-resistant S. aureus (MSSA and MRSA) isolates was evaluated.

Results:

A total of 310 pediatric patients were examined. Overall, 225 (72.6%) isolates were MSSA and 85 (27.4%) were MRSA. All S. aureus isolates were susceptible to teicoplanin, vancomycin, linezolid, tigecycline, mupirocin, and daptomycin. Penicillin resistance rates were high (89.0%), while fosfomycin, gentamicin, and clindamycin resistance rates were low (1.3%, 1.0%, and 2.3%, respectively). Except susceptibility to fosfomycin, which was significantly lower in 2014 compared to 2018 and 2019, no significant difference was found in the antimicrobial susceptibility of S. aureus isolates between the years. Baseline characteristics and mortality rate were similar comparing MRSA and MSSA causing HCAIs. The mortality rate of HCAIs caused by S. aureus was 6.5% (20 patients). Malignancy was an independent risk factor associated with mortality in the multivariate analysis (OR 5.446, 95% CI 1.573-18.849).

Conclusions:

Our findings demonstrate that MSSA remained the most causative agent of HCAIs caused by S. aureus. The mortality rate was 6.5%, the antibiotic resistance rate was quite high for penicillin and diagnosis of malignancy was the main risk factor for increasing mortality in children. These findings could help improve the management of HCAIs caused by S. aureus in children.
Knowledge, Attitude and Behavioural Survey Regarding Oral Hygiene Practices amongst Rural and Urban Population of Ahmedabad City, Gujarat: A Comparative Study
Authors: Patel Eshita Dasharathbhai , Parikh Hiral Akshat , Joshi Keyur H , Soni Prerna , Unjia Alay , Soni Maahi , Mehta Isha
Published: September 2023

Introduction:

It is thought that oral hygiene can be influenced by socioeconomic status to some extent. People with higher socioeconomic status often have better access to resources and opportunities, which can impact their oral hygiene practices and overall dental health. Hence, this study assessed knowledge, attitude and behaviour regarding oral health amongst the adult population in urban and rural populations of Ahmedabad city.

Materials and Methods:

This cross-sectional study was carried out amongst the urban and rural segments of Ahmedabad district. The zones of the district and participants were selected by systematic random sampling method. The participants in the Ahmedabad district were selected, and those 204 who fulfilled the inclusion criteria were considered. A validated questionnaire was designed in our study so as to satisfy the quality, attain the objective of our study and make the study effective.

Results:

About 70.42% of the rural population and 77.30% of the urban population has good knowledge, while only 36.1% of the rural population and 47.16% of the urban population had a positive attitude towards oral hygiene practices. 61.27% of the rural population and 64.81% of the urban population showed positive behaviour. The absence of correlation was identified between knowledge-attitude and attitude-behaviour.

Conclusion:

It has been found that a massive number of the urban population possess a higher level of knowledge and attitude towards oral health than the rural population. No linear positive correlation was seen in knowledge, attitude and behaviour towards oral health.
Development and Validation of Unmada Symptom Checklist
Authors: Patil Suchitra S. , Singh Amit , Nagarathna R. , Nagendra H. R.
Published: September 2023

Background:

Psychosis is explained as Unmada in Ayurveda Medical Science. Types of Unmada are based on Tridosha. General and a specific symptom of Unmada have been explained in classics exclusively. Unmada is alteration in mental functions such as behavior, emotions, intellect, memory, and character. The symptoms of Unmada are (1) Mano vibhrama - altered functions of mind, (2) Buddhi vibhrama - altered discriminative power, judgment, (3) Sanjañā jñāna vibhrama - altered consciousness, (4) Smriti vibhrama - confused memory, (5) Bhakti vibhrama - altered attachment or embellishment, (6) Śīla vibhrama - altered nature or disposition, (7) Cheshta vibhrama - altered motion or gesture, and (8) Ācāra vibhrama - altered custom or practice. Many scales such as the Brief Psychiatry Rating Scale (BPRS) and positive and negative symptom scale are available from the modern perceptive. According to the Ayurveda perceptive, Unmada-specific symptom scale to measure Tridosha in psychotic patients is available, but there is a need for a standard scale to measure general symptoms so that the treatment for behavior, emotions, intellect, and memory can be planned as per the derangement. Hence, this study has been taken.

Aims and Objective:

The objective of the study was to develop a simple, standardized instrument to assess symptoms of Unmada according to the Ayurveda concepts in the diagnosed patients of psychosis.

Methods:

This was a descriptive type of study to develop a scale. A 54-item, Unmada symptom checklist (USC) was developed based on symptoms description in Ayurvedic classics and by taking the opinions of experts (five Ayurvedic experts, five psychiatrists, and five psychologists). It was evaluated in 30 patients with the diagnosis of nonaffective psychosis to check the reliability of the instrument. Moreover, the scale was administered on 30 patients who were diagnosed with psychosis. The duration for administration was about 20–25 min.

Results:

The reliability of a USC was good which was supported by high internal consistency values of Cronbach’s α – 0.9144. Correlation between total scores of BPRS and US was 0.959 and P<0.001, which was considered as statistically significant. Interrater reliability coefficient for each item ranged from 0.627 to 0.951. Correlation, which measures of criterion related validity, was 0.950 with BPRS, which suggested that Ayurveda concepts correlate with modern concepts.

Conclusions:

An USC is a simple, efficient, reliable, and valid instrument for clinicians to diagnose Unmada in patients according to the Ayurveda concept. However, further research with more number of samples, more diverse groups of psychotic disorders, and a broader range of convergent and discriminant validity are needed.
Development and Validation of Self-Recorded Swasthya Assessment Scale
Authors: Panda Prajna Paramita , Harti Shivakumar S. , Rao Mangalagowri V.
Published: September 2023

Background:

The Self-Recorded Swasthya Assessment Scale (SRSAS) is intended to develop a comprehensive questionnaire to assess the health status of an individual. SRSAS has three sections, namely physical, mental, and social health.

Materials and Methods:

The questionnaire has been prepared based on physical, mental, and social health parameters. In section 1, the questions of the physical fitness component are derived from International Fitness Scale and the questions of physical ill-health component are prepared on the basis of Swastha criteria described in literature from Charaka Samhita, Sushruta Samhita, and Kashyapa Samhita. In section 2, the mental toughness questions are prepared based on Ayurveda parameters and MTQ-48 and mental ill-health questions are prepared from Ayurveda parameters and guidelines of the American Psychiatric Association (2013), Diagnostic and Statistical Manual of Mental Disorders 5th Edition. The health status will be assessed based on the self-recorded response of the subjects. The time frame for the questions is the PAST WEEK. The questionnaire is designed to assess subject's USUAL abilities in their routine environment.

Results:

The questionnaire was administrated on 117 individuals. The data collected were statistically analyzed for internal consistency by Cronbach's alpha and for sampling adequacy by Kaiser–Meyer–Olkin (KMO) test. The Cronbach's alpha for the fitness group of questions and ill-health group of questions were 0.832 and 0.799, respectively. The KMO value for the fitness group of questions and ill-health group of questions were 0.791 and 0.588, respectively.

Conclusion:

The Cronbach's alpha and KMO value showing the internal consistency and sampling adequacy are acceptable. It is concluded that the questionnaire is reliable and valid to use to assess the health status of an individual according to Ayurveda.
Standardization of Bindu Pramana for Nasya
Authors: Balagopal Aiswarya , Sukumar Bargale Sushant
Published: September 2023

Introduction:

Nasya (nasal administration of medication) is one of Dinacharya (daily regimen) mentioned by Acharyas. Two Bindu is considered the recommended dose of Pratimarsha Nasya (done as a part of daily regimen). Bindu is defined as the total quantity of liquid medicine that dribbles down when the first two digits of index finger (distal and middle phalanges) are dipped into it and taken out of the same. Considering the above definition of Bindu, it is evident that Bindu Pramana varies from person to person probably due to the variation in size of one’s index finger and also viscosity of the liquid used for Nasya.

Materials and Methods:

A total of 405 apparently healthy subjects with body mass index (BMI) between 18.5 and 24.9 kg/m2 coming under the age group of 18–60 years were selected. The subjects had to dip their index finger up to middle interphalangeal joint in Anu Taila, Tila Taila, and Sarshapa Taila one after the other. The whole amount of Taila (oil) that dripped down after dipping finger was collected in a watch glass and sucked into calibrated syringe for further calculations.

Results:

The Bindu Pramana for subjects with BMI range within 18.50–24.99 kg/m2 was found to be 0.55 ml (12.4 drops) for Tila Taila, 0.57 ml (12.4 drops) for Anu Taila, and 0.56 ml (11.8 drops) for Sarshapa Taila.

Conclusion:

This study of standardization of Bindu Pramana for Nasya concluded that Bindu Pramana for subjects with BMI range within 18.50–24.99 kg/m2 is 0.6 ml which is approximately 12 drops for all three Taila.
Ayurvedic Management of Vicharchika (Lichen Simplex Chronicus) - A Case Report
Authors: Singh Neelam Kumari , Sengar Alok Singh , Khuntia Bipin Bihari
Published: September 2023

Lichen simplex chronicus (LSC) consists of lichenified scaly plaque due to chronic scratching. The available conventional treatments are various topical antipruritic agents and corticosteroids, which are associated with high rates of treatment failure and complications because trans-epidermal drug absorption is limited. LSC manifests as a significant challenge to a physician due to persistent itching and therapeutic resistance. In Ayurveda, this condition has a close resemblance to Vicharchika. Vicharchika is a type of Kshudra kustha with dominancy of Kapha dosha characterized by redness, itching, pain, cracks, and dryness. In this case report, a 48 year old female reported complaints of multiple black-colored patches on the dorsum surface of bilateral feet with severe itching for 6 years. Local examination revealed lichenified hyperpigmented plaques with erythematous bases and well-defined edges covered by white scales with central excoriation. Plaques were found bilaterally over the dorsum of feet and malleolus. Based on symptoms and signs, the case of LSC was diagnosed. This case was managed effectively with Ayurvedic internal medications such as Arogyavardhini Vati, Kaishore Guggulu, Nishaamlaki Vati, Triphala churna, Khadirarishta, and local application of Brihat Marichyadi oil and Sudha Gandhak. The outcome assessment was based on improvement in the size of skin patches, hyperpigmentation, thickening, and itching. Complete improvement has been observed in symptoms after 4 months of regular treatment. No adverse effect pertaining to the prescribed drug was reported during the study period. Ayurvedic medicines offer a good approach to managing LSC.
Staining characteristics of the lid margin
Authors: Kamel Anhar M. , Shafik Heba M. , Awara Amr M. , Shalaby Osama E.
Published: September 2023

Background

Vital stains are very important for evaluation of Marx line (ML) location, regularity, and lid wiper epitheliopathy. ML score can be used to assess Meibomian gland function, whereas lid wiper epitheliopathy is considered an early indicator for tear film instability.

Aim

To evaluate staining characteristics of the lid margin in different disease conditions, such as dry eye, Meibomian gland dysfunction (MGD), and eyelid malposition using vital stains.

Patients and methods

A total of 80 patients aged between 40 and 60 years were included in this study. Patients were already diagnosed as having dry eye, MGD, and eyelid malposition (ectropion and entropion). Vital stains (fluorescein, rose Bengal, and Lissamine green) were used to assess the lid wiper area and ML position in these diseases.

Results

The included 80 participants comprised 44 females and 36 males aged from 40 to 60 years, with mean±SD of 45.10 ± 5.42 years for normal participants, and it was 47.35 ± 6.57 years for dry eye participants. ML was straight in 75% of normal group, but it was irregular in 65% of the dry eye group, 100% of the malposition group, and 70% of MGD group. Lid wiper epitheliopathy was mild degree in one-third of normal participants. In dry eye participants, it was moderate and severe (45% for each).

Conclusion

ML is irregular and moved gradually anterior to the eyelid margin with different diseases such as dry eye, MGD, and eyelid malposition. Lid wiper epitheliopathy provides information about the location of ML, and it can be easily seen by using the vital staining, and it is useful in the diagnosis of tear film instability.
Evaluation of cerebral hemodynamic alterations by transcranial Doppler in neonatal sepsis
Authors: Rowisha Mennat-Allah M. , El Mahdy Heba S. , El Barbary Aly A. , Dawoud Tamer M.
Published: September 2023

Background

Transcranial Doppler is a noninvasive approach with high temporal resolution, permitting continuous cerebral blood flow velocity recording through major cerebral arteries.

Aim

To determine cerebral blood flow (CBF) changes in neonatal sepsis (NS) by ultrasound (US) Doppler examination.

Patients and methods

This prospective case–control trial was conducted on 60 neonates who were divided into two groups: group I (sepsis): 32 neonates with NS diagnosed by clinical and laboratory data and group II (control): 28 healthy neonates with gestational age and sex matched. All cases underwent detailed antenatal and natal history, clinical and laboratory investigations and transcranial Doppler examination with assessment of CBF.

Results

As regards anterior cerebral artery (ACA) and middle cerebral artery (MCA), peak systolic velocity (PSV) (cm/s) and end-diastolic velocity (EDV) (cm/s) were significantly increased in the sepsis group than in the control group (P<0.001), but both resistive index and pulsatility index were significantly decreased, in the sepsis group than in the control group (P<0.001). Validity of MCA PSV with a cut-off point of 55.4 detects a sensitivity of 94% and specificity of 86%; validity of MCA EDV with a cutoff point of 18 detects a sensitivity of 94% and specificity of 89%; validity of ACA PSV with a cutoff point of 49.3 detects a sensitivity of 88% and specificity of 93%; validity of ACA EDV with a cutoff point of 21 detects a sensitivity of 91% and specificity of 93%.

Conclusion

NS was found to elevate both PSV, EDV, decrease resistivity, and pulsatility indices causing an elevated CBF and a decreased resistance.
Classification of global solutions of a free boundary problem in the plane
Authors: Dipierro Serena , Karakhanyan Aram L. , Valdinoci Enrico
Published: September 2023

We classify non-trivial, non-negative, positively homogeneous solutions of the equation

\Delta u=\gamma u^{\gamma-1}

in the plane. The problem is motivated by the analysis of the classical Alt–Phillips free boundary problem, but considered here with negative exponents

\gamma

. The proof relies on several bespoke results for ordinary differential equations.
Aspects of noncommutative geometry of Bunce–Deddens algebras
Authors: Klimek Slawomir , McBride Matt , Peoples J. Wilson
Published: September 2023

We define and study smooth subalgebras of Bunce–Deddens

C^∗

-algebras. We discuss various aspects of noncommutative geometry of Bunce–Deddens algebras including derivations on smooth subalgebras, as well as

K

-theory and

K

-homology.
Cocompact embedding theorem for functions of bounded variation into Lorentz spaces
Authors: Zhao Lin
Published: September 2023

We show that the embedding

\dot{\mathrm{BV}}(\mathbb{R}^N)\hookrightarrow L^{1^\ast,q}(\mathbb{R}^N)

,

q>1

is cocompact with respect to the group and the profile decomposition for

\dot{\mathrm{BV}}(\mathbb{R}^N)

. This paper extends the cocompactness and profile decomposition for the critical space

L^{1^\ast}(\mathbb{R}^N)

to Lorentz spaces

L^{1^\ast,q}(\mathbb{R}^N)

,

q>1

. A counterexample for

\dot{\mathrm{BV}}(\mathbb{R}^N)\hookrightarrow L^{1^\ast,1}(\mathbb{R}^N)

not cocompact is given in the last section.
Coherent sheaves, Chern classes, and superconnections
on compact complex-analytic manifolds
Authors: Bondal Alexey Igorevich , Rosly Alexei Andreevich
Published: September 2023

A twist-closed enhancement of the bounded derived category
$\mathcal{D}^b_{\mathrm{coh}} (X)$
of complexes of $\mathcal{O}_X$-modules
with coherent cohomology is constructed by means of the DG-category of
$\overline\partial$-superconnections. The machinery of
$\overline\partial$-superconnections is applied to define Chern classes and
Bott-Chern classes of objects in the category, in particular,
of coherent sheaves.
Early neonatal complications in pregnant women with gestational diabetes mellitus and the effects of glycemic control on neonatal infection
Authors: Wang Bei-Bei , Xue Mei
Published: September 2023

Diabetes and associated complications represent major global public health issues which are associated with impaired quality of life and premature death. Although some diabetic complications have decreased in the developed world, the majority are still prevalent, with an increasing trend in the developing world. Currently used therapies are mainly ‘glucocentric’, focusing on the optimization of glycemic control to prevent, delay or manage diabetes-associated complications- other common comorbidities, such as dyslipidemia and hypertension are often underestimated. Although a number of novel therapeutic approaches have been reported recently, some of them have not received comparable attention in relation to either further studies or potential clinical implementation. This editorial briefly discusses some recent therapeutic approaches to the prevention and management of diabetes and its associated complications, as well as potential directions for future research and development in this area.
Risk factors of concurrent urinary sepsis in patients with diabetes mellitus comorbid with upper urinary tract calculi
Authors: Gou Jian-Jie , Zhang Chao , Han Hai-Song , Wu Hong-Wei
Published: September 2023

Diabetes and associated complications represent major global public health issues which are associated with impaired quality of life and premature death. Although some diabetic complications have decreased in the developed world, the majority are still prevalent, with an increasing trend in the developing world. Currently used therapies are mainly ‘glucocentric’, focusing on the optimization of glycemic control to prevent, delay or manage diabetes-associated complications- other common comorbidities, such as dyslipidemia and hypertension are often underestimated. Although a number of novel therapeutic approaches have been reported recently, some of them have not received comparable attention in relation to either further studies or potential clinical implementation. This editorial briefly discusses some recent therapeutic approaches to the prevention and management of diabetes and its associated complications, as well as potential directions for future research and development in this area.
Post-Collision Run-Out Vehicle Deceleration Based on Real-World
Data
Authors: Fuerbeth Uwe
Published: September 2023

In traffic accidents, the run-out is the phase after impact until reaching a
final rest position. Analyzing and reconstructing this phase is a task leading
sometimes to a broad bandwidth of results. This can be due to the unknown
driver’s reaction and braking behavior. The well-known literature describes
rollout decelerations, but these exclude the influence of the driver,
particularly with regard to accident situations. Measurement data from
real-world collisions can help quantifying the vehicle’s deceleration during the
run-out and thus at least partially close the existing research gap. Therefore,
this study deals with the systematic evaluation of real-world measurement data
from intersection collisions collected by accident data recorders. The
high-frequency acceleration and speed data of 45 accident vehicles with impact
velocities up to 70 kph were processed for this purpose; characteristic values
for the run-out phase were calculated in each case and then statistically
evaluated. Results in terms of mean deceleration rates are presented as well as
conclusions about driver’s post-collision behavior. On the one hand, the data
reveal that it is extremely unlikely that a vehicle will not be actively braked
by the driver during run-out and, on the other hand, that braking with maximum
deceleration is also unlikely. The results indicate a mean resultant run-out
deceleration with respect to time of 4.5 m/s2 and with respect to
distance of 4.1 m/s2. This means more intensive braking by human
drivers after a collision than typical deceleration in normal everyday driving
activities and is comparable to intervention of advanced driver-assistance
systems. These findings can assist the reconstructionist analyzing intersection
accidents in quantifying or narrowing down the level of deceleration of a
vehicle in run-out and for this reason the driver’s post-collision behavior.