bluuebunny/crossref_metadata_2025 huggingface dataset:
A kinematic model linking the Sevier and Laramide belts in the Idaho-Montana fold-thrust belt, U.S. Cordillera
Authors: Parker Stuart D. , Pearson David M.
Published: October 2023

The Sevier and Laramide belts of the U.S. Cordillera are differentiated based on thin- and thick-skinned structural domains, commonly inferred to have formed under different plate-boundary conditions. However, spatial and temporal overlap in the Idaho-Montana fold-thrust belt suggests that thin- and thick-skinned thrust systems are kinematically linked. We present the first balanced and sequentially restorable cross section that integrates the Sevier and Laramide belts. Encompassing most of the width of the Cordilleran retroarc, our kinematic model accounts for at least 244 km of horizontal shortening, linking thin- and thick-skinned thrust systems. We hypothesize that thin strata overlying the Lemhi arch basement high determined the geometry and relative timing of the later thrusting. Early shortening (pre–ca. 90 Ma) was thin skinned, with the décollement of the Medicine Lodge–McKenzie thrust system following Devonian shales on top of the Lemhi arch unconformity. Displacement on upper thin- and lower thick-skinned thrusts overlapped between ca. 90 and 70 Ma as a mid-crustal décollement was activated, efficiently transmitting strain through the Lemhi arch to the Blacktail-Snowcrest uplift in the foreland. A regional-scale duplex (Patterson culmination) linked the lower and upper décollements, internally thickening and increasing the basal slope of the orogenic wedge. Thick-skinned thrusts of the Dillon cutoff (Hawley Creek, Cabin, and Johnson thrusts) eventually thickened the wedge and exhumed the abandoned upper décollement. Following this, the thick-skinned wedge advanced in-sequence from ca. 70 to 55 Ma. This kinematic model establishes continuity between thin- and thick-skinned thrust systems by a mid-crustal décollement. In this model, the stratigraphic thicknesses of sedimentary cover rocks limit the availability of décollement horizons, determining the style of mountain building and triggering a slow transition from thin- to thick-skinned thrusting.
Acute safeguarding essentials in modern-day paediatrics: neglect, unsupervised minors and modern slavery
Authors: Thomas Helen , Cromb Daniel , Jacob Hannah
Published: October 2023

As part of a case-series exploring acute safeguarding essentials in modern day paediatrics, this article focusses on themes of neglect, unsupervised minors and modern slavery. Considerations around initial management, relevant legislation and useful resources, and available to all professionals involved in safeguarding children.
Early detection of neurodevelopmental disorders in African children living in informal settlements in Nairobi
Authors: Segre Giulia , Cargnelutti Cecilia , Bersani Carlotta , Njogu Washington , Roberti Elisa , Campi Rita , De Vita Maria Vittoria , Morino Gianfranco , Canevini Maria Paola , Bonati Maurizio
Published: October 2023

Background

Children in low-income and middle-income countries (LMICs) are at a substantially increased risk of delayed physical, emotional and sociocognitive outcomes, with consequential neurodevelopmental disorders. Evidence based, cost-effective and culturally appropriate screening tools are recommended for early identification of developmental disorders.

Methods

The present study aims to assess the feasibility of early screening for neurodevelopmental disorders in children living in informal settlements in Nairobi, Kenya (Korogocho). The selected tools (ie, the CDC checklist and the Modified Checklist for Autism in Toddlers, Revised (M-CHAT-R)), widely used in high-income countries, are applied in two different populations: one from Kenya (LMIC) and one from Italy, to compare the different scores.

Results

Of 509 children screened, 8.6% were classified at-risk based on the results of the screening tools. Significant risk factors are history of low birth weight and Apgar score, presence of neurological disorders, malnutrition and/or rickets, younger age of the child and older age of the mother. Caesarean section delivery, first pregnancy and mothers’ older age were common risk factors among the Kenyan and the Italian samples. The Italian sample had a significantly greater rate of missed milestones.

Conclusions

Our data demonstrate the feasibility of using the CDC and M-CHAT-R tools in informal settlement dwellers. Further studies are needed to explore the opportunity for early diagnosis of developmental disorders in LMICs.
Study on Kalb–Ramond field localization in f(T) gravity theory with a noncanonical scalar field
Authors: Sorkhi Masoumeh Moazzen , Ghalenovi Zahra
Published: October 2023

In this paper, we investigate the localization of five-dimensional tensor gauge fields called Kalb–Ramond fields in the modified teleparallel braneworld models. The aforementioned branes are generated by gravity coupled to a real scalar field with nonstandard kinetic terms. For two specific forms of the noncanonical expressions, background scalar field solutions are particularly discussed in the presence of different forms of [Formula: see text] gravity. By applying nonminimal coupling functions in the tensor gauge field action, it is shown that massless zero modes of Kalb–Ramond gauge fields can be localized on the [Formula: see text] branes with noncanonical scalar fields. We also find that potentials of Kalb–Ramond massive modes are volcano-like regarding the equation of motion in the supersymmetric quantum mechanic scenario. Furthermore, the effects of parameters that control the deviation of the usual teleparallel theory are considered on the massless Kaluza–Klein mode and effective potential.
Methodology of evaluating ATLAS computing resources in handling user analysis workflows
Authors: Grigoryeva Maria
Published: October 2023

The distributed computing infrastructure of the ATLAS Experiment includes over 170 sites and executes up to 3 million computing jobs daily. PanDA (Production and Distributed Analysis) is the Workload Management System responsible for task and job execution; its key components are the broker and job scheduler that define the mapping of computing jobs to the resources. The optimization of this mapping is crucial for handling the expected computational payloads during the HL-LHC era. Considering the heterogeneity and the distributed structure of the Worldwide LHC Computing Grid (WLCG) infrastructure that provides computing resources for analyzing the data, there is a need for specific approaches for evaluating computing resources according to their ability to process different types of workflows. This evaluation can potentially enhance the efficiency of the Grid by optimally distributing different types of payloads in heterogeneous computing environments. To tackle this challenge, this research proposes a method for evaluating WLCG resources regarding their ability to process user analysis payloads. This evaluation is based on leveraging available information about job execution on PanDA queues within the ATLAS computing environment.
Classification of Ecological Garden Scenes Using Deep Learning in Remote Sensing Images
Authors: Wang Xiaoyu , Liu Shaohui
Published: October 2023

Ecological garden is one of the important links of urban ecosystem. Accurate and effective analysis of temporal and spatial changes of garden vegetation is conducive to the sustainable development of urban resources and environment. However, the elements of garden vegetation are close to each other, and the current analysis methods can’t support the remote sensing image analysis in the ecological garden scene. To solve this problem, this paper introduces a new method for recognition and classification based on deep learning networks. Firstly, radiometric correction and geometric correction are used to preprocess the data collected by unmanned aerial vehicle (UAV); the ecological garden remote sensing image analysis network is constructed based on three-dimensional convolutional neural network (3D-CNN), which adopts double convolution pool structure, To address the issue of pixel misclassification due to similar features in landscape vegetation classification, a deep learning network can be used for high-dimensional feature extraction. On this basis, the multiple label conditional random field (MLCRF) algorithm can be applied for global optimization, effectively solving the misclassification problem caused by similar features of vegetation. This method not only improves classification accuracy but also is suitable for large-scale image classification tasks in complex scenes. The simulation results show that the overall recognition accuracy of the proposed 3D-CNN-MLCRF identification method is 97.83% and the Kappa coefficient is 97.18%, which can accurately and effectively realize the task of ecological garden scene classification.
Classification of Arrhythmic and Normal Rhythm FECG Signal Based on Ensemble Features and Dense Networks
Authors: Breesha S. R. , Vinsley S. S.
Published: October 2023

The fetal electrocardiogram (FECG) signal carries several key pieces of information that could help clinicians make accurate decisions during labor. In order to make effective fetal monitoring, the detection of FECG signals is more important. However, the detection and classification of FECG signals are complicated tasks due to inappropriate learning ability. Thus, the proposed study aims to develop an efficient deep learning model for offering prenatal treatment to arrhythmic fetus by classifying the FECG signals. The input FECG signals are pre-processed in the initial stage using the Least Extended Mean Square Algorithm (LEXSA) to eliminate the awful noises. These pre-processed signals are fed to the input of the Ensemble Wavelet Empirical Component (EnSem_WEC)-based feature extraction stage, where the respective features are attained by applying Empirical Mode Decomposition (EMD), Independent Component Analysis (ICA) and Wavelet Transform (WT). The extracted features select the essential feature subset to avoid the high dimensionality issues through Enhanced Moth Flame Optimization (EMoFo) algorithm. Finally, the FECG signals are classified using the selected features by proposing a new Dense Attention-based Stacked Bi-directional Long Short Term Memory network model (DA_SBi-LSTM). The model is optimized by tuning the hyperparameter using the Pelican Optimization Algorithm (POA). The simulation analysis proves that the proposed deep learning model attained higher classification performance in terms of accuracy of 98.93%, precision of 97.5%, recall of 97.5%, and F1-score of 97.8%. As compared with other existing methods, the proposed techniques attained superior classification outcomes.
Optimal Energy Management of Parking Lots in Microgrid to Reduce Operation Cost by Dynamic Parameters Lightening Search Algorithm
Authors: Lamouki Hamid Ghobadi , Shokouhandeh Hassan , Kamarposhti Mehrdad Ahmadi , Matankolaei Fariba Asghari , Padmanaban Sanjeevikumar , Kang Sun-Kyoung , Colak Ilhami
Published: October 2023

In this paper, a dynamic parameters lightning search algorithm (DP-LSA) is proposed for optimal operation management of electric vehicle (EV) parking lots (PLs) and distributed generations (DGs) in a microgrid (MG). The MG comprises distributed generation sources such as diesel generators and fuel cells. The batteries of electric vehicles parked in the PL are also used for energy storage. A proposed objective function combines operating, maintenance, and replacement costs, considering inflation, motivation, and annual growth. Simulations are done in two scenarios, and the proposed algorithm results are compared with particle swarm optimization (PSO) algorithm results. Simulation results prove the better performance of the proposed LSA algorithm than the PSO algorithm in reducing the microgrid operation cost.
Metamorphosed mélange in the eastern Himalayan syntaxis: constraint for the India–Asia collision in the Eocene
Authors: Wei Zhen , Li Xianghui , Sun Minjia , Fan Xiaolong , Wang Jingyu , Zhou Juanjuan , Wei Shoucai
Published: October 2023

Tectonic mélanges are crucial for deciphering collision processes in orogenic belts. This study investigates the nature of the metamorphosed mélange in the Milin area of the eastern Himalayan syntaxis to shed light on the India–Asia collision in the region. The mélange exhibits a ‘block-in-matrix’ fabric in the lower and upper parts and a ‘lenticular-thrust-slices’ fabric in the middle. Quartzite blocks in the lower part are proposed to be Silurian or younger quartz arenites with a Tethyan affinity. Metacherts and amphibolites in the middle and upper parts may have originated from hydrothermal or terrestrial cherts and Nb-enriched basalts in the Asian forearc or syncollisional basin at ∼48–45 Ma. The diverse blocks/slices of the mélange, sourced from both the subducting and overriding plates, are suggested as having formed during Indian plate subduction. The protoliths of the amphibolite–metachert slice (∼45 Ma) in the mélange are distinctly different from the contemporary shallow sea (post-collisional) deposits but similar to the deep-water (initial collisional or pre-collisional) sediments in other parts of the suture zone. This implies that the amphibolite–metachert slice may represent the product of the initial India–Asia collision or even pre-collision and that (hard) collision likely lagged by ∼10 Myr in the eastern Himalaya syntaxis.

Supplementary material:
Analytical methods, Figures S1–S5 showcasing field occurrences, cathodoluminescence images of zircons, and geochemical characteristics, Table S1 – geochronology data, Table S2 – zircon Lu–Hf isotopic data, and Table S3 – whole-rock major and trace element results are available at
https://doi.org/10.6084/m9.figshare.c.6896942

Thematic collection:
This article is part of the Ophiolites, melanges and blueschists collection available at:
https://www.lyellcollection.org/topic/collections/ophiolites-melanges-and-blueschists
Late Devonian syntaxis in the Northern Appalachian orogen
Authors: Piette-Lauzière Nicolas , Larson Kyle P. , Kellett Dawn A. , Harris Lyal , Cleven Nathan , Rogers Neil
Published: October 2023

The pre-accretionary shapes of cratonic margins form successions of promontories and re-entrants inherited from the rifting of supercontinents. In accretionary orogens, the extent of deformation related to a collision with a continent characterized by an irregular margin is obfuscated through the partitioning of deformation along pre-existing structures. In the Northern Appalachians, the extent of the deformation related to the oblique collision of the Meguma terrane with the composite Laurentian margin is disputed. Herein, we use a framework based on modern collisional settings to investigate the Late Devonian to Mississippian deformation inboard of the Avalonia–Meguma boundary and evaluate the regional tectonic setting. We combine published shear zone kinematic interpretations, deformation ages and regional
40
Ar/
39
Ar cooling ages with structural interpretation of aeromagnetic and gravimetric depth slices covering the Northern Appalachians. We find that the deformation related to the collision of the Meguma terrane, attributed to the Neoacadian orogeny, has a larger structural footprint than previously documented. While this deformation is partitioned in multiple structures in the Canadian Appalachians, northern New England is characterized by rapid crustal deformation, high palaeoelevation and fast erosional exhumation, similar to modern syntaxis structures.
Shopping Around for Loot Box Presence Warning Labels: Unsatisfactory Compliance on Epic, Nintendo, Sony, and Microsoft Platforms
Authors: Xiao Leon Y.
Published: October 2023

Loot boxes are gambling-like products in video games that players can buy with real-world money to obtain random prizes. Many countries are concerned by their potential harms and are considering regulation. Industry self-regulation of companies’ own behavior is an alternative approach to direct government intervention through legislation. The self-regulatory age rating organizations in North America and Europe began assigning a loot box presence warning label (“In-game Purchases (Includes Random Items)”) since April 2020. This consumer protection measure has also been introduced to many digital storefronts. My recent study found that only 29% of popular games containing loot boxes were correctly labeled on the Google Play Store. The age rating organizations have seemingly suggested that other digital storefronts with significantly less content would, in contrast, perform significantly better. The present study found that the compliance rates were indeed higher on the Microsoft (89.1%), Sony (70.3%), and Nintendo (54.2%) stores. However, none met the target 95% compliance rate. Concerningly, the Epic Games Store's compliance rate was only 7.1%. Some remedial actions have been taken following the present study: while appreciated, they have failed to address all outstanding concerns. Companies and platform providers must better comply with and enforce the rules. Besides poor efficacy on mobile platforms, the industry self-regulatory loot box warning label is also not sufficiently reliable on PC and console platforms.
Estimating Degradations of La0.57Sr0.38Co0.2Fe0.8O3-δ
Oxygen Diffusion and Surface Exchange Coefficients by Effective Reaction Thickness
Authors: Shimura Takaaki , Komatsu Yosuke , He An , Sciazko Anna , Shikazono Naoki
Published: October 2023

The degradation of La0.57Sr0.38Co0.2Fe0.8O3-δ
(LSCF) cathode is investigated by focusing on the change in effective reaction thickness. The durability tests showed severe degradation for the thinner electrodes, which suggests that the degradation in surface exchange coefficient (k) is the dominant degradation factor rather than the bulk diffusion coefficient (D). For the quantitative evaluation of k and D, the electrochemical impedance spectroscopy analyses demonstrated that the degradation rate of k was larger than that of D, and both degraded larger for thinner electrodes. The changes in effective reaction thickness are estimated by numerical simulation with the obtained degradation rates of D and k. The effective reaction thickness elongated in thinner electrodes due to the excessive decrease in k. This implies that the degradation is accelerated in thinner electrodes where effective reaction thickness exceeds physical electrode thickness and larger local overpotential is imposed.
Short-Time Fourier Transform Analysis of Current Charge/Discharge Response of Lithium-Sulfur Batteries
Authors: Allagui Anis , Awadallah Osama , El-Zahab Bilal , Wang Chunlei
Published: October 2023

Measurements acquired on batteries in the form of time signals such as voltage-time and capacity-time to assess their cyclability performance can be supplemented by examining their frequency-domain response. This allows one to determine the global characteristics of the signals and the battery, but not the local behavior, which is very important for determining for example battery fading. In this study we examine the short-time Fourier transform for time-frequency deconstruction of galvanostatic charge/discharge signals of lithium-sulfur batteries, taken as an example. The results displayed in terms of spectrograms show how the frequency content of such signals (e.g. charge and voltage time series) evolve with the lifetime of the batteries allowing the detection of critical changes in the response that may lead to fading and eventually default.
Health Systems Barriers to the Implementation of Preventing Mother-to-Child Transmission of Human Immunodeficiency Virus Infection in Primary Health Care Facilities in Ghana
Authors: Sarpomaa Osei Beatrice , Agyei-Baffour Peter , Mensah Kofi Akohene , Twum Peter
Published: October 2023

Background. Ghana has implemented the prevention of mother-to-child transmission strategy (PMTCT) to control HIV infection transmission to babies. However, this has not yielded the desired results, as there are still many mother-to-child HIV infection cases being reported due to factors such as those related to health system barriers. This study was, therefore, conducted to identify health system barriers to the implementation of PMTCT in selected districts in the Ashanti Region of Ghana. Methods. A cross-sectional study was conducted among 118 health workers in 20 selected health facilities within the Asante-Akim Central and South Municipalities in the Ashanti Region, Ghana, to assess the health system barriers to the prevention of mother-to-child transmission of HIV/AIDS. Data was collected using a structured, self-administered questionnaire, which was later transferred to Kobo Collect software. The study participants were chosen using multistage sampling approaches. The data cleaning and analysis were done using STATA version 16.1. Multiple logistic regression models, chi-square analysis for normality testing, and descriptive analysis were all used. The results were displayed in tables, and a p-value of 0.05 was used to determine the significance level. The study was carried out from June to September 2022. Results. In all, 118 participants were involved in this study. Of this, 57.4% had a good level of knowledge of PMTCT, even though all of them were aware of PMTCT. We found being more than 40 years (Odds Ratio, OR = 2.08 95% CI: 1.05, 5.00) and being in service with Ghana Health Service for more than 15 years (OR = 2.36 95% CI: 0.51,10.84) to be significant predictors of knowledge on PMTCT among our participants. A greater proportion of our participants revealed inadequate staffing as the major challenge faced in the delivery of PMTCT in Ashanti Region. Increased education on PMTCT was the most suggested solution to improve the management of HIV infection among pregnant women and further enhance the success rates of PMTCT in Ashanti Region, Ghana. Conclusions. The majority of the health professionals had good knowledge about the prevention of mother-to-child transmission. However, the number of staff in the two districts was not adequate, which affected public education. It is therefore important to increase the number of staff to enhance educating the public and minimize the transmission rate in the districts and the country as well.
Comparative Estimation of Nutritionally Important Chemical Constituents of Red Seaweed, Gracilariopsis longissima, Affected by Different Drying Methods
Authors: Ullah Md. Rahamat , Akhter Mousumi , Khan Abu Bakker Siddique , Yasmin Farhana , Hasan Md. Monjurul , Bosu Aovijite , Haque Mohammed Ashraful , Islam Md. Mohidul , Islam Md. Amirul , Mahmud Yahia
Published: October 2023

In this study, the nutritional and phytochemical components of red seaweed, Gracilariopsis longissima, were assessed in relation to the effects of various drying methods (freeze, oven, and sun). Gracilariopsis longissima’s proximate composition differed significantly (

P

 < 0.05) among the three drying techniques, with freeze-dried samples having significantly greater protein (30.63 ± 0.90% dry weight) and lipids (1.49 ± 0.05% dry weight) contents. Except for phosphorus and sulfur, the mineral concentrations were likewise considerably greater in the freeze-dried samples. The total amino acids (30.48 ± 0.06% dry weight) and fatty acids contents were substantially greater (

P

 < 0.05) in the freeze-dried samples. In freeze-dried samples, the levels of essential amino acids (18.92 ± 0.02% dry weight) and unsaturated fatty acids (54.08 ± 0.07%) were substantially greater (

P

 < 0.05). When compared to oven- and sun-dried samples, the total phenolic content (88.70 ± 2.19 mg GAE/g dry weight) and the flavonoid content (71.46 ± 2.17 mg QE/g dry weight) of freeze-dried samples was also substantially higher. Among the three distinct drying techniques used, the freeze-drying technique kept G. longissima’s higher nutritional and phytochemical components.
Social Support and Posttraumatic Growth among Postoperative Patients with Breast Cancer: A Latent Profile and Moderated Mediation Analysis
Authors: Gu Yingxuan , Bie Fenggui , Hu Meixia , Huang Linfeng , Chen Jiaping , Hu Xiaohui , Luo Caixia , Ye Zengjie
Published: October 2023

Objectives. Only a few studies have explored the association between social support and resilience, coping style, and posttraumatic growth (PTG) in breast cancer. The current research aimed to identify the latent subtypes of social support in patients with breast cancer (BC) who underwent surgery. Moreover, the mediating role of resilience and the moderating role of coping style were investigated. Methods. This cross‐sectional study enrolled 115 patients from Be Resilient to Breast Cancer between September 2021 and April 2022 using the convenience sampling method. Then, the Perceived Social Support Scale, Connor–Davidson Resilience Scale, Medical Coping Modes Questionnaire, and Posttraumatic Growth Inventory were utilized. A latent profile analysis and a moderated mediation analysis were performed. Results. Three subtypes of social support were identified as low (16.5%), middle (53.0%), and high (30.4%). Social support, resilience, and coping style were found to be positively associated with PTG (r = 0.373, P < 0.01; r = 0.427, P < 0.01; r = 0.218, P < 0.05). Resilience played a significant role in mediating the association between social support and PTG (P < 0.05). However, coping style did not significantly moderate the association between resilience and PTG (P > 0.05). Conclusions. Heterogeneous subgroups of social support have been identified in patients with BC. Resilience significantly mediates the association between social support and PTG. Meanwhile, coping style does not significantly moderate the association between resilience and PTG.
Landscape of Baseline and Acquired Genomic Alterations in Circulating Tumor DNA with Abemaciclib Alone or with Endocrine Therapy in Advanced Breast Cancer
Authors: Goetz Matthew P. , Hamilton Erika P. , Campone Mario , Hurvitz Sara A. , Cortes Javier , Johnston Stephen , Llombart-Cussac Antonio , Kaufman Peter A. , Toi Masakazu , Jerusalem Guy , Graham Hillary , Wang Hong , Jansen Valerie M. , Litchfield Lacey M. , Martin Miguel
Published: October 2023

Purpose:

To identify potential predictors of response and resistance mechanisms in patients with hormone receptor–positive (HR+), HER2-negative (HER2−) advanced breast cancer (ABC) treated with the cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor abemaciclib ± endocrine therapy (ET), baseline and acquired genomic alterations in circulating tumor DNA (ctDNA) were analyzed and associated with clinical outcomes.

Experimental Design:

MONARCH 3: postmenopausal women with HR+, HER2− ABC and no prior systemic therapy in the advanced setting were randomly assigned to abemaciclib or placebo plus nonsteroidal aromatase inhibitor (NSAI). nextMONARCH: women with HR+, HER2− metastatic breast cancer that progressed on/after prior ET and chemotherapy were randomly assigned to abemaciclib alone (two doses) or plus tamoxifen. Baseline and end-of-treatment plasma samples from patients in MONARCH 3 and nextMONARCH (monotherapy arms) were analyzed to identify somatic genomic alterations. Association between genomic alterations and median progression-free survival (mPFS) was assessed.

Results:

Most patients had ≥1 genomic alteration detected in baseline ctDNA. In MONARCH 3, abemaciclib+NSAI was associated with improved mPFS versus placebo+NSAI, regardless of baseline alterations. ESR1 alterations were less frequently acquired in the abemaciclib+NSAI arm than placebo+NSAI. Acquired alterations potentially associated with resistance to abemaciclib ± NSAI included RB1 and MYC.

Conclusions:

In MONARCH 3, certain baseline ctDNA genomic alterations were prognostic for ET but not predictive of abemaciclib response. Further studies are warranted to assess whether ctDNA alterations acquired during abemaciclib treatment differ from other CDK4/6 inhibitors. Findings are hypothesis generating; further exploration is warranted into mechanisms of resistance to abemaciclib and ET.

See related commentary by Wander and Bardia, p. 2008
Kidney Biopsy Findings and Clinical Outcomes of US Veterans with Inflammatory Bowel Disease
Authors: Ravipati Prasanth , Reule Scott , Bren Alyssa , Bu Lihong , Vaughn Byron P , Nachman Patrick H.
Published: October 2023

Introduction: Patients with inflammatory bowel disease (IBD; ulcerative colitis [UC] and Crohn’s disease [CD]) may have unique patterns of kidney injury related to their underlying or coexisting disease or to medications. We present the kidney biopsy findings and clinical outcomes of veterans with UC or CD from the US Department of Veteran’s Affairs (VA) health system. Methods: Histopathologic and clinical data were extracted by retrospective review of the VA electronic health record of patients with IBD and a kidney biopsy between 2000 and 2018. Incident end-stage kidney disease (ESKD) was defined as requirement of kidney replacement therapy. Statistical analyses were performed using SAS. Results: A total of 140 patients (UC: 91 and CD: 49) underwent kidney biopsy. The three most common diagnoses were IgA nephropathy (17.1%), diabetic nephropathy (14.3%), and acute interstitial nephritis (9.3%). Significant interstitial fibrosis, tubular atrophy, and arteriosclerosis were present in 45% of biopsies. Twenty-six percent of patients with UC and 20% of those with CD progressed to ESKD, with a mean time from kidney biopsy of 3.1 and 1.9 years, respectively. Forty-five percent of patients with UC and 34% of those with CD died, with a mean time from kidney biopsy of 4.3 and 4.6 years, respectively. Conclusion: Among US veterans with IBD who underwent a kidney biopsy, IgA nephropathy, diabetic nephropathy, and interstitial nephritis were among the most common findings. Additionally, features of advanced kidney disease with rapid clinical progression to ESKD or death were observed. These findings suggest a delay and possibly a low rate of diagnosis.
Neurocognitive Function with Conventional Hemodialysis versus Post-Dilution Hemofiltration as Initial Treatment in ESKD Patients: A Randomized Controlled Trial – The DA-VINCI Study
Authors: Jimenez Enzo Vasquez , Nuñez Guadalupe Campos , Lerma Abel , Lerma Claudia , Gonzalez Aloha Meave , Perez-Grovas Hector , Gil Salvador López , Madero Magdalena
Published: October 2023

Introduction: The ideal modality choice and dialysis prescription during the first renal replacement therapy (RRT) session remain unclear. We conducted a pilot study to determine the safety risk for hemodialysis (HD) versus hemofiltration (HF) and its relationship with neurocognitive assessment on incident RRT patients. Methods: Twenty-four incident RRT patients were included. Patients were randomized to the conventional HD group or post-dilution HF group. Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MOCA) tests were applied in all patients before and after session, and brain magnetic resonance image (MRI) was performed in 7 patients from the conventional HD group and 8 patients from the post-dilution HF group before and after the intervention. Results: Baseline characteristics were similar between groups. Compared to conventional HD, post-dilution HF had longer treatment time. There were no significant changes in blood pressure after RRT in both groups. The MMSE test showed no significant differences between groups or within groups. The MOCA test showed an increase in the total score for the post-dilution HF group with no significant changes between groups. The MRI evaluation showed no differences between or within groups. Conclusion: Post-dilution HF is a safe alternative for the first HD session in incident RRT; it allows longer treatment time if ultrafiltration is required and has a similar neurological risk than conventional HD. This is a pilot study and that larger studies are needed to confirm the findings.
Expression of Apelin and Apelin Receptor Protein in the Hypothalamo-Pituitary-Ovarian Axis during the Estrous Cycle of Mice
Authors: Anima Borgohain , Gurusubramanian Guruswami , Roy Vikas Kumar
Published: October 2023

Introduction: Apelin is an endogenous peptide, whose expression has been shown in the hypothalamus, pituitary, and ovary; furthermore, it is also called a neuropeptide, binding to apelin receptor (APJ) for various functions. It has been suggested that the hypothalamus, pituitary, and ovarian (HPO) axis is tightly regulated and factors and functions of the HPO axis can be modulated during the estrous cycle to influence reproductive status. To the best of our knowledge, the status of apelin and its receptor, APJ has not been investigated in the HPO axis during the estrous cycle. Methods: To explore the expression of apelin and APJ in the HPO axis of mice during the estrous cycle, mice were divided into four groups: proestrus (Pro), estrus (Est), metestrus (Met), and diestrus (Di), and apelin and APJ were checked. Further, to explore the role of apelin in gonadotropin secretion, an in vitro study of the pituitary was performed at the Pro and Est stages. Result: The expression apelin and APJ in the hypothalamus showed elevation during the estrous cycle of postovulatory phases, Met, and Di. The immunolocalization of apelin and APJ in the anterior pituitary showed more abundance in the Est and Di. Our in vitro results showed that gonadotropin-releasing hormone agonist stimulated luteinizing hormone secretion was suppressed by the apelin 13 peptide from the pituitary of Pro and Est phases. This suggests an inhibitory role of apelin on gonadotropin secretion. The ovary also showed conspicuous changes in the presence of apelin and APJ during the estrous cycle. The expression of apelin and APJ coincides with folliculogenesis and corpus luteum formation and the expression of the apelin system in the different cell types of the ovary suggests its cell-specific role. Previous studies also showed that apelin has a stimulatory role in ovarian steroid secretion, proliferation, and corpus luteum. Conclusion: Overall our results showed that the apelin system changes along the HPO axis during the estrous cycle and might have an inhibitory at level of hypothalamus and pituitary and a stimulatory role at ovarian level.
Às voltas com as poses de Sylvia Molloy
Authors: Sousa Pacelli Dias Alves de
Published: October 2023

Este artigo tem como objetivo apresentar uma reflexão sobre a categoria de pose na obra da escritora e crítica literária argentina Sylvia Molloy, tendo em vista as suas modulações em diferentes textos, sejam de criação literária ou de crítica e teoria literária. Defendo que há três zonas da pose em sua obra: por um lado, a pose como ação cotidiana significante, especialmente em seus textos literários; ainda, a ideia de política da pose, desde um olhar que tensiona os cruzamentos entre a literatura e os questionamentos de sexualidade e gênero; e, finalmente, a epistemologia da pose, como salto interpretativo para se compreender o próprio processo de elaboração da pose como problematização, como gesto diferenciado e objeto de reflexão do conhecimento. Procuro apontar ainda alguns paralelos com outras teorias, particularmente com leituras do pós-estruturalismo francês e com certa zona de filosofia e crítica que se constituía à época (e em alguns casos veio a ser lida posteriormente) como queer.
Roland Barthes: a crítica como uma resposta ativa e o "método do jogo"
Authors: Giordano Alberto
Published: October 2023

Este artigo é uma reescrita de uma das aulas do curso "Roland Barthes y la escritura del duelo", no âmbito de uma leitura do Journal de deuil (1977-1979) do crítico francês, prestando atenção aos impulsos diarísticos que reconfiguram, no registro, as aflições e as experiências do autor. Nestas, há uma insistência que é reconhecida nas últimas obras de Barthes, aquelas em que ocorre uma notável virada autobiográfica: a necessidade de responder de forma ativa à afirmação da linguagem literária sobrevive - e sobrevém. Essa disposição é, na lógica barthesiana, um desvio da força esmagadora exercida pela crítica como instituição, cujas operações tendem a generalizar e totalizar. O método dessa resposta ativa é o "método do jogo", um paradoxo: resgatar, por meio de experimentação formal, os gestos irreduzíveis e irreverentes do não produtivo, do aleatório, daquilo que coloca em jogo o corpo do ensaísta crítico. Este último diz respeito, em particular, à forma deste artigo. Aqui, a entrada no Journal não se esgota no progresso expositivo da aula, mas sim uma busca ensaística está por trás dela. A leitura adquire, assim, no curso, a modalidade de um excurso, do que está nas bordas, do que está fora.
Você não entendeu nada: perverformativos e cenas do ensino na Universidade de São Paulo
Authors: Saldanha Fabio Pomponio
Published: October 2023

o artigo tenta demonstrar como teorias surgidas nos anos 1960 e 1990 foram recebidas na USP. Tendo como foco a desconstrução (mais especificamente o nome próprio Jacques Derrida), teorias feministas e pós-coloniais (traduzidas pelo guarda-chuva Estudos Culturais), tenta-se construir, a partir de textos produzidos pela academia uspiana, o quadro de rejeição observado através da exclusão da diferença. O foco se torna o papel da instituição enquanto aquela que ensina o/a aluno/a a reproduzir uma forma genérica de leitura em volta dessas teorias, ao se notar que o que passa a ser ali reproduzido é uma repetição da repetição advinda de outras leituras de leituras, na medida na qual o que se busca fazer é impedir algo já em curso: a chegada de tais teorias dentro da academia. A partir de textos de Paulo Eduardo Arantes e Leyla Perrone-Moisés, investiga-se qual face/imagem a respeito da desconstrução e dos Estudos Culturais se formou na USP e qual é o papel do humor e do professor dentro de tais cenas de ensino, quando se pensa tanto o humor quanto a ameaça como ferramentas de dominação, ora sim, ora não, implícitas.
Os "Jimbandas" em um Defeito de Cor sob a Perspectiva da Analítica Quare e da Decolonialidade
Authors: Santos Vinícius Ferreira dos
Published: October 2023

O presente estudo tem por objetivo analisar os personagens Jongo e Adriano no romance Um defeito de cor (2006) de Ana Maria Gonçalves, sob a perspectiva da analítica quare, que insere a interseccionalidade no escopo das teorias queer. Ambos são denominados de “jimbandas” pela voz narrativa em primeira pessoa, que os situa no campo das relações homossexuais. Tal palavra parece apresentar um histórico significativo, pois surge já em documentos da Santa Inquisição em suas operações no Brasil colonial. Apesar disso, ela designa um grupo identitário provavelmente ainda pouco visibilizado nos estudos críticos de literatura brasileira. Nesse sentido, a obra de Gonçalves presentifica o debate acerca das vivências homossexuais de africanos em diáspora, evidenciando o modo como a política regulatória de corpos de um país patriarcal-cristão colocava sob vigilância sexualidades e expressões de gênero dissidentes. A partir da abordagem da decolonialidade, este trabalho também pretende apresentar certo giro epistêmico, inserindo o sujeito dissidente como produtor de um discurso científico corpo-geolocalizado.
RE(A)PRESENTAÇÕES DO DEBATE PÚBLICO SOBRE GÊNERO NO JORNALISMO BRASILEIRO: VISIBILIDADES ALARGADAS E APAGAMENTOS EM COMENTÁRIOS JORNALÍSTICOS
Authors: Scabin Nara Lya Cabral
Published: October 2023

Este artigo busca compreender como discussões relacionadas a situações, vivências e problemáticas enfrentadas por grupos minorizados a partir de marcadores de gênero são representadas, entre 1978 e 2018, por veículos do chamado jornalismo de referência, elegendo, como universo de investigação, os jornais O Estado de S. Paulo, O Globo e Folha de S. Paulo. Indaga-se, especialmente, sobre as mediações construídas sobre a emergência de uma discursividade contemporânea que remodela concepções políticas e assume posição de concorrência em relação a discursos da modernidade. A partir de um corpus de 81 comentários jornalísticos, procura-se identificar isotopias semânticas indicativas dos discursos circulantes sobre gênero que atravessam e constituem a encenação do diálogo social na imprensa de referência no Brasil.
FAKE NEWS POLÍTICA NO BRASIL: DA FICHA FALSA DA DILMA À DEEPFAKE DO JORNAL NACIONAL
Authors: Souza Vinicius Guedes Pereira de
Published: October 2023

O artigo reflete sobre as manipulações de imagens visuais midiáticas e sentimentos do eleitorado a partir da teoria de mudança no modo de pensamento da humanidade (FLUSSER, 2008 e 2009), de tempo-histórico-linear para mágico-imagético-circular. Para tanto, cita e analisa exemplos históricos (BARTHES, 1961) na imprensa estadunidense e nacionais como o caso da ficha falsa de Dilma Rousseff na capa da Folha de S. Paulo em 2009 (SOUZA, 2012), a disputa narrativa entre o “Pavão Misterioso” e o The Intercept Brasil em 2019 (SOUZA; PEREIRA, 2020), e o caso da falsificação em vídeo da pesquisa IPEC sobre as intenções de votos no primeiro turno das eleições de 2022.
A CONQUISTA DE ESPAÇO: AS MULHERES NO RÁDIO SANTARENO
Authors: Borges Leandro , Carvalho Mônica
Published: October 2023

O presente trabalho tem como tema A Conquista de Espaço: As Mulheres no Rádio Santareno. A finalidade é mostrar a importância da mulher na locução do rádio, permitir o acesso ao mercado de trabalho, as oportunidades têm favorecido somente os homens. O objetivo do trabalho é investigar a ausência da mulher dentro do rádio, compreender o motivo. O resultado mostra que a brasileira quer ingressar no rádio, porém a oportunidade não concedida o desinteresse da empresa na contratação, quando é chamada para ocupar cargo, passa por algum constrangimento. Conclui-se que o mercado não escolhe gênero, a voz hoje no rádio não é tão fundamental como antes.
Propuesta de indicadores para la evaluación de la reputación en el Tercer Sector
Authors: Renau María Pallarés , López-Font Lorena
Published: October 2023

Este artículo presenta el Modelo RTS1 (Medidor de la Reputación para las entidades del Tercer Sector de Acción Social –TSAS–), que se caracteriza por cinco dimensiones configuradas por treinta atributos, susceptibles de ser evaluadas por 12 públicos que estuvo compuesto por más de cincuenta colectivos. Un instrumento que parte de MERCO y Reptrak (monitores de referencia) y atiende a la idiosincrasia del TSAS y voluntad informativa de Cáritas, Cruz Roja, Fundación OXFAM Intermón, Fundación Save The Children y Fundación UNICEF Comité Español (entidades de notable relevancia en España) para ser contrastado con tres perfiles de expertos (profesionales de la consultoría de comunicación, académicos y cargos de responsabilidad en ONG).
Información, tecnología y pensamiento crítico
Authors: Garcia Maria Laura
Published: October 2023

Columna de opinión de María Laura García, empresaria e inversora. Fundadora y presidenta de GlobalNews® Group, presidenta del Comité Empresarial del World Innovation and Change Management Institute (WICMI) y miembro del consejo asesor de la comunidad de emprendedores Inicia y del Board de Voces Vitales Cono Sur. Ha sido presidenta de FIBEP (FEDERATION INTERNATIONALE DES BUREAUX D'EXTRAITS DE PRESSE).
Para “ver” o que faz a prefeitura: comunicação pública no Instagram da prefeitura de Florianópolis
Authors: Comel Naiza , Moura Júlia Frank de
Published: October 2023

Este artigo analisa de que forma a prefeitura de Florianópolis utiliza o Instagram como ferramenta de comunicação pública. Para isso, realizou-se análise de conteúdo de 66 posts publicados entre janeiro e julho de 2022. Os resultados apontam que o tom das postagens é majoritariamente informativo e os tipos mais recorrentes de postagens são de serviços e orientações – o que demonstra a preocupação da prefeitura com uma comunicação pública normativa. Entre os temas, destacam-se saúde, cultura e turismo.
Novas perspectivas em avaliação e mensuração de resultados em Relações Públicas e Comunicação Organizacional
Authors: Nobell Alejandro Álvarez , Adi Ana , Castillo-Esparcia Antonio , Stoeckle Thomas , Lopes Valéria de Siqueira Castro
Published: October 2023

Apresentação.
A travessia do deserto: verdade e não-saber em Pornoteobrasil, do Tablado de Arruar
Authors: Kon Artur Sartori
Published: October 2023

Este ensaio analisa a peça teatral Pornoteobrasil, estreada pela companhia paulistana Tablado de Arruar em janeiro de 2019, primeiro mês do governo de Jair Bolsonaro. Observa-se como a arte pode estar à altura da urgência do tempo histórico sem pretender oferecer respostas e soluções prontas para os impasses que ele apresenta. Essa investigação nos permite ver o teatro político contemporâneo como pós-brechtiano, localizando a transformação do mundo não no plano das possibilidades, mas no campo do impossível.
Paisagens sonoras: memórias de uma cidade fabril (Rio Grande, RS - 1950-1970)
Authors: Mazzucchi Ferreira Maria Leticia , Nery Olivia Silva
Published: October 2023

The article discusses the constitution of the industrial soundscape of the city of Rio Grande, Rio Grande do Sul, based on two textile factories: Rheingantz and Ítalo-brasileira (1950 – 1970). The text analyzes how this landscape is evoked by former workers and residents, starting from sound signals such as the factory whistle and others that refer to the factory universe. The article is based on the concept of soundscape by Raymond Murray Schafer, approaching what the author translates as “acoustic community.” Methodologically, the article is based on the field of the history of sensibilities and on the importance of the sensorial regime for social relations. The results of the article point to a sound inventory, to the diversity of emotions and perceptions involved, and highlight the role that sounds play in memorial and identity construction.
“Lei de Irrigação” (1959) da Sudene: desapropriação e questão fundiária no Nordeste
Authors: Pinto Gustavo Louis Henrique
Published: October 2023

A “Lei de Irrigação” foi o primeiro instrumento de regulação legislativa proposto pela Operação Nordeste, em 1959, e representa a gênese do enfrentamento da questão agrária pela Sudene. O debate e a aprovação desse projeto pelo Conselho Deliberativo do Codeno, órgão que precedeu a Sudene, expõe as disputas políticas em torno da possibilidade de desapropriação de terras, opondo as elites algodoeiras-pecuaristas cearenses ligadas ao DNOCS ao projeto da Sudene. Este trabalho analisa a formulação da “Lei de Irrigação” (PL nº 882/1959) a partir das atas do Conselho Deliberativo, observando seus antecedentes, a coalizão entre governadores nordestinos, Exército, empresários industriais, Igreja Católica e técnicos do DNOCS, assim como a reação cearense e o debate legislativo nos anos de 1959 e 1960 que obstaculizou sua aprovação. A proposta de desapropriações das áreas irrigadas com financiamento público, apesar de ser histórica na região e ser um projeto de reforma agrária moderada em sua extensão, expõe a questão fundiária latente ao projeto e o seu consequente impedimento.
A teologia política de Giovanni Antonio Andreoni, o Antonil
Authors: Zeron Carlos Alberto de Moura Ribeiro
Published: October 2023

Resenha do Livro: GIULI, Matteo. L’opulenza del Brasile coloniale. Storia di un trattato di economia e del gesuita Antonil. Roma: Carocci Editore, 2021. 316 p.