bluuebunny/crossref_metadata_2025 huggingface dataset:
Antibiotic resistance rates of Klebsiella pneumoniae strains isolated from urine cultures
Authors: Aytaç Özlem
Published: April 2024

Aim: Our study aimed to determine the antibiotic resistance rates of K. pneumoniae by retrospectively examining the results of urine culture samples studied in our laboratory.
Methods: Urine samples with K. pneumoniae growth, sent to our laboratory from various wards, outpatient clinics, and intensive care units between July 1, 2018 and December 31, 2022 were included in the study and retrospectively examined.
Results: The antibiotic to which K. pneumoniae was most resistant was cefixime (53.3%), and the antibiotic to which it was least resistant was imipenem (12.1%). While the lowest resistance rates were observed in the samples of outpatients, the highest resistance rates were observed in the samples of ward patients and to cefixime (81%), amoxicillin clavulanic acid (AMC) (80%), trimethoprim-sulfamethoxazole (TMT/SXT) (74.8%), and ciprofloxacin (72.1%). Ertapenem (48.9%), meropenem (50.2%) and piperacillin-tazobactam (PRP) (57.3%) resistance was found to be higher in intensive care patients.
Conclusion: Although fluctuations in resistance rates have been observed over the years, resistance rates have generally been found to be high for antibiotics frequently used in the empirical treatment of urinary tract infections. Re-adjusting treatment according to culture results and keeping resistance rates in mind for empirical treatment will be important for treatment success.
Optical coherence tomography angiography changes in patients with hemoglobinopathy
Authors: Özer Ömer , Güçlü Emin
Published: April 2024

Aim: The aim of this study is to evaluate retinal vascular changes in patients with sickle cell disease (SCD) and beta-thalassemia with optical coherence tomography angiography (OCT-A).
Methods: For this purpose, 98 patients with SCD, 75 patients with beta-thalassemia, and 100 healthy controls in Mersin University Hospital between January 1, 2020, and November 1, 2021, were included in this study. OCT-A imaging was performed with ZEISS AngioPlex OCT angiography (Carl Zeiss Meditec, Dublin, CA, USA).
Results: All OCT-A parameters (FAZ area, perimeter, circularity, vessel, and perfusion density) were found to be statistically significantly different in both patients with thalassemia and patients with sickle cell disease when compared to the controls.
Conclusions: In conclusion, retinopathy related to both hemoglobinopathy subgroups can be diagnosed and followed up with OCT-A. It was also found that OCT-A parameters are affected before the development of clinically detectable retinopathy.
Evaluation of patient satisfaction following oral glucose tolerance test
Authors: Gökbulut Püren , Bilen Habib , Akbaş Emin Murat , Özdemir Çigdem , Gökbulut Volkan , Koç Gönül
Published: April 2024

Aim: Diabetes mellitus (DM) is a common metabolic disease. Early diagnosis of diabetes prevents the increase in mortality and morbidity due to complications. The oral glucose tolerance test (OGTT) is a test used in the diagnosis of DM and in the determination of impaired glucose tolerance (IGT). In our study, it was aimed to evaluate the satisfaction of patients who underwent OGTT.
Methods: A 25-question questionnaire was applied to 300 patients who underwent OGTT, aiming to evaluate their satisfaction. The physical and psychological status of the patients was examined before, during, and after the test.
Results: Patients who were informed about the test before the test experienced less nausea during fluid intake (p=0.005). Approximately 58.7% of the participants agreed to repeat the test. Those who felt nauseous or hungry during the test were statistically less likely to accept retesting. The retest acceptance rates were statistically higher (p<0.05) among individuals who did not feel uncomfortable with the blood draw and inactivity and who did not vomit or feel uneasy during the test. 70% of the participants answered 'yes' to the suggestion of using an alternative diagnostic method.
Conclusion: OGTT is the gold standard for the diagnosis of IGT and DM, despite tests such as HbA1c and fasting plasma glucose, which are more easily performed and practical. It would be beneficial to develop another method that is easy to apply, better tolerated by patients, easy to repeat, and can be standardized instead of OGTT.
Comparative Performance Evaluation of Magnetron Sputtered TiN, AlCrN, and TiAlCrN Coatings
Authors: Montwedi Baitsi , Jeje Samson , Shongwe Mxolisi
Published: April 2024

This study presents a comparative performance evaluation of magnetron-sputtered TiN, AlCrN, and TiAlCrN coatings on tool steel substrates. Coatings play a pivotal role in enhancing the durability of engineering components exposed to harsh conditions. TiN is known for outstanding hardness and durability, AlCrN for superior wear resistance, and TiAlCrN for exceptional thermal stability and oxidation resistance. The substrate (EN 1.2363) underwent PVD coating using a closed-field unbalanced magnetron sputter ion plating (CFUBMSIP) process in a water-cooled stainless-steel vacuum chamber with four magnetron ports, operating for 3 hours per batch followed by 12 hours of natural convection cooling, utilizing TiN, AlCrN, and TiAlCrN films deposited for 180 minutes in an Ar and nitrogen atmosphere. X-ray diffraction (XRD) revealed distinctive crystal structures, with all coatings exhibiting a common preferred orientation of the (111) plane and TiAlCrN showing a ternary nitride phase. Scanning electron microscopy (SEM) images displayed the compact nature of TiAlCrN with finer grains, while TiN exhibited a densely compacted with no evidence of delamination and AlCrN showed denseness with smaller grains. Nano-indentation test was conducted to assess the coatings' hardness and elastic modulus. TiAlCrN exhibited the highest hardness (3091±243 HV), highest elastic modulus (369.86±54.19 GPa), and the best wear rate (0.1887 x 10-4 mm3/Nm-1) suggesting potential suitability for applications demanding superior rigidity and wear resistance. The study provides valuable insights for materials scientists and engineers in optimizing coating selection for specific applications.
Assessment of Buckling Failure in Oil Storage Tanks: Finite Element Simulation of Combined Internal and External Pressure Scenarios
Authors: Mashiyane Themba , Tartibu Lagouge , Salifu Smith
Published: April 2024

Investigating the structural behaviour and buckling susceptibility of cylindrical oil storage tanks is crucial for ensuring their safe and reliable operation. In this study, the structural behaviour and buckling susceptibility of closed roof-top cylindrical oil storage tanks under combined internal and external pressure scenarios were investigated using the finite element analysis (FEA) technique. By utilizing the FEA technique, the combined effect of wind-induced pressure of 250 Pa, applied on the outer surface of the tank and internal pressure of 0.5 MPa, applied on the outer surface of the storage was analysed. The result reveals significant stress concentrations and deformation patterns, particularly on the windward side of the tank, thus, emphasizing the susceptibility of the storage tank to buckling under the specified operating conditions for both the filled and half-filled tank; with internal pressure emerging as the primary contributor to mechanical strain and deformation experienced in the tank, while the wind load plays a secondary but significant role in the deformation of the tank. The fe-safe predicted useful life shows that under the specified operating conditions, the filled storage tank will survive 1 429 hours (2 months) while the half-filled tank will survive 3 551 hours (5 months) before failure due to buckling. Thus, the useful life estimation results show the importance of varying oil levels and operating conditions in the structural assessments of storage tanks.
O compliance à luz da inclusão social da pessoa com deficiência
Authors: Muniz Fuzetto Murilo , Marques de Medeiros Neto Elias
Published: April 2024

Este artigo trata-se de pesquisa realizada para discorrer, através do método dedutivo, sobre o papel do compliance em prol da inclusão social da pessoa com deficiência por meio do trabalho. Os programas de integridade surgiram inicialmente para coibir e evitar atos de corrupção nos ambientes empresariais com vistas de conter os danos que poderiam vir a ser causados. Com o seu aprimoramento, percebeu-se a sua utilidade para outros aspectos, tais como a melhoria da imagem perante a sociedade e na busca por um ambiente laboral hígido e sustentável. As pessoas com deficiência viveram segregadas por séculos, necessitando que o Estado tutele seus direitos e crie e fomente mecanismos de inserção. Com base nisso, tem-se que o compliance poderá ser importante ferramenta para cumprir as normas de acessibilidade no ambiente empresarial e as demais políticas públicas, além de programar outros instrumentos em prol da inclusão social atendendo os Princípios da Isonomia e da Dignidade da Pessoa Humana.
A lesão especial (Art. 157 CC/2022) e os contratos de compra e venda de participação societária em sociedades limitadas
Authors: Tomazette Marlon , Garcia Guedes Marilia
Published: April 2024

O presente artigo trata da intersecção entre o instituto da lesão especial, art. 157 do Código Civil de 2002, e os contratos que envolvam a aquisição de participação societária em sociedade limitada. O trabalho analisa se em tais operações econômicas, materializadas em instrumento contratual cujo escopo é sempre lucro para todos os envolvidos, há espaço para incidência de vício de consentimento decorrente de premente necessidade, inexperiência ou leviandade, máxime levando-se em consideração a necessidade de diligência do comprador. Após uma revisão bibliográfica e normativa do tema, analisam-se julgados, os quais apontam a necessidade de diligência por parte do adquirente, do cuidado com a redação das cláusulas – preferencialmente por advogados – e a não presunção da inexperiência dos agentes econômicos que negociam no âmbito empresarial, tampouco a necessidade de contratar de maneira premente. Não são localizados acórdãos que reconheçam a incidência da lesão especial no âmbito empresarial quanto à aquisição de quotas de sociedade limitada e, em verdade, quanto a nenhum outro contrato de natureza mercantil.
Profil Penderita Liken Simpleks Kronis di Poliklinik Kesehatan Kulit dan Kelamin Rsud Dr. Mohamad Soewandhie Surabaya Periode Januari 2020-Desember 2021
Authors: Dilafarah Winny , Pramita Desy Hinda
Published: April 2024

Penelitian ini bertujuan untuk mengetahui profil penderita LSK yang berobat ke Poliklinik Kesehatan Kulit dan Kelamin RSUD dr. Mohamad Soewandhie Surabaya yang mencakup distribusi frekuensi berdasarkan usia, jenis kelamin, keluhan utama, lama keluhan, lokasi lesi, dan riwayat penyakit dahulu. Penelitian ini adalah penelitian deskriptif dan dilakukan secara retrospektif dengan melihat rekam medis pasien LSK di Poliklinik Kesehatan Kulit dan Kelamin RSUD M. Soewandhie Surabaya pada periode Januari 2020-Desember 2021. Populasi pada penelitian ini adalah pasien baru yang berkunjung pada Poliklinik Kesehatan Kulit dan Kelamin RSUD M. Soewandhie Surabaya pada periode Januari 2020-Desember 2021. Pengambilan sampel pada penelitian ini menggunakan teknik total sampling sebanyak 36 pasien pada tahun 2020 dan 69 pasien pada tahun 2021. Hasil penelitian diperoleh distribusi frekuensi penderita LSK berdasarkan kelompok usia terbanyak adalah > 65 tahun (30,48%) dengan jumlah pasien perempuan lebih banyak (53,33%) daripada laki-laki (46,67%). Keluhan utama terbanyak yaitu gatal (100%). Lama keluhan terbanyak yaitu selama > 12 bulan (40,95%). Lokasi lesi tersering terjadi pada kaki (63,64%). Riwayat penyakit dahulu terbanyak adalah Dermatitis Atopi (21,25%). Hasil penelitian ini menunjukkan distribusi frekuensi penderita LSK masih banyak dan terdapat pengaruh faktor internal yang memengaruhi terjadinya LSK.
Penerapan Balanced Scorecard Sebagai Model Pengukuran Kinerja dalam Konteks Administrasi Publik
Authors: Kardina Mutia , Syamsir Syamsir
Published: April 2024

Balanced Scorecard (BSC) telah menjadi alat yang penting dalam mengukur kinerja organisasi, tidak hanya dalam sektor swasta tetapi juga dalam konteks administrasi publik. Penelitian ini mengulas tentang penerapan BSC sebagai model pengukuran kinerja dalam administrasi publik. Melalui pendekatan ini, penelitian ini bertujuan untuk mengeksplorasi bagaimana BSC dapat diterapkan secara efektif dalam lingkungan pemerintahan. Dengan memanfaatkan kerangka kerja BSC, aspek-aspek kinerja kunci yang relevan dengan tujuan-tujuan strategis pemerintah dapat diidentifikasi dan diukur secara terukur. Implementasi BSC dalam administrasi publik menawarkan pendekatan yang holistik untuk mengelola kinerja, dengan memperhatikan berbagai perspektif seperti keuangan, pelanggan, proses internal, dan pembelajaran dan pertumbuhan. Hal ini memungkinkan para pemangku kepentingan untuk memahami kinerja organisasi secara menyeluruh dan menyediakan dasar yang kuat untuk pengambilan keputusan strategis. Selain itu, penggunaan BSC dapat membantu dalam membangun transparansi, akuntabilitas, dan fokus pada pencapaian tujuan-tujuan yang relevan dengan kepentingan publik. Dengan demikian, penelitian ini akan membahas tentang relevansi dan manfaat penerapan BSC dalam konteks administrasi publik serta tantangan yang mungkin dihadapi dalam proses implementasinya. Melalui penjelasan ini, diharapkan dapat memberikan wawasan yang lebih dalam tentang bagaimana BSC dapat menjadi alat yang berharga dalam meningkatkan kinerja organisasi pemerintah dan mencapai tujuan-tujuan strategis yang ditetapkan.
Proses Manajemen Pengetahuan dalam Pendidikan: Sebuah Penelitian Teoritis-Konseptual
Authors: Pringgabayu Dematria , Ramadhian Mochamad Arief Rahman
Published: April 2024

Manajemen Pengetahuan (KM) adalah subjek yang telah membangkitkan minat banyak peneliti dalam dekade terakhir, karena kontribusinya yang besar didorong oleh langkah-langkah yang disebut proses KM. Karena merupakan tema yang merangkul, publikasi tentang proses KM memiliki kontribusi multidisiplin dan, oleh karena itu, penelitian ini bertujuan untuk mengkonseptualisasikan proses ini, menganalisis pendekatan utama yang memandu studi pada setiap tahapan, dan juga, untuk mengangkat publikasi utama mengenai subjek tersebut. mengklasifikasikannya berdasarkan area kontribusinya. Untuk mencapai tujuan tersebut, artikel ini berorientasi pada penelitian teoritis-konseptual, dimana 71 artikel dipelajari. Hasilnya menunjukkan bahwa proses KM terdiri dari empat tahap: perolehan, penyimpanan, distribusi, dan penggunaan pengetahuan. Pada tahap akuisisi, tema yang dipelajari adalah pembelajaran organisasi, permulaan pengetahuan, proses kreatif dan transformasi pengetahuan. Pada fase penyimpanan, kontribusi berkaitan dengan seseorang, organisasi dan teknologi informasi, sedangkan pada fase distribusi, studi berkonsentrasi pada tema kontak sosial, praktik komunitas, dan berbagi melalui teknologi informasi. Dan yang terakhir, pada fase penggunaan, kami membahas bentuk penggunaan, kapasitas dinamis, pengambilan, dan transformasi pengetahuan.
Klinik Ujian Wadah Pembentuk Karakter Mahasiswa Menghadapi Ujian Akhir Semester
Authors: Agus Prasetya Suci , Dewi Anggralita Sandra , Ummah Maslachatul
Published: April 2024

Tujuan diselenggarakan penelitian Klinik Ujian bagi mahasiswa baru adalah, untuk memberikan pemahaman, pengetahuan tentang cara mempersiapkan UASUT, misal cara membaca effektif. SQ3R, bagaimana belajar Effektif di UT, mengelola waktu yang effektif. Sehingga setelah memasuki menjelang Ujian Akhir Semester dan belajar, mahasiswa baru memahami layanan akademik, administrasi dalam rangka persiapan UAS di UT. Penelitian ini menggunakan metode penelitian kualitatif, di mana fokus penelitiannya menggunakan jenis penelitian studi kasus, karena kasusnya menarik, menjadi perhatian publik khususnya UT pusat. Pendekatan penelitian melalui kualitatif adalah salah satu prosedur penelitian yang menghasilkan data diskriptif berupa ucapan, atau tulisan dan perilaku orang-orang yang diamati. Tehnik pengambilan data penelitian ini, dengan tehnik wawancara mendalam (Indepth Interview), snowball sampling pada mahasiswa, pengelola. Untuk mendukung pelaksanaan penelitian, peneliti menggunakan kajian teori Konstruksi Sosial Thomas Lukcman ang Berger T. Novelty penelitian yakni diperlukan Konstruksi Sosial melalaui training test Klinik Ujian yang harus dikerjakan, sesuai kaidah dalam belajar di UT, hal tersebut berakibat pada hasil UAS berdampak prestasi mahasiswa Pendas maupun Non Pendas Universitas Terbuka meningkat.
Peran Bimbingan Belajar dalam Meningkatkan Motivasi Belajar dan Sikap Keagamaan Anak
Authors: Dewi Diah Deandra , Fuad Ai Fatimah Nur , Nurjanah Nurjanah
Published: April 2024

Tujuan penelitian ini adalah untuk mengetahui bagaimana standar pembelajaran dapat mendukung perkembangan sikap keagamaan positif anak dan peningkatan motivasi belajar. Penggunaan pembelajaran berbasis bermain khususnya dapat memotivasi siswa untuk memecahkan masalah dengan lebih aktif dan kreatif. Melalui penggunaan pendekatan studi pustaka sebagai sumber data, tujuh publikasi penelitian tahun 2016 hingga 2022 yang berkaitan dengan topik penelitian diteliti guna mengumpulkan data sekunder berupa uraian fakta dan alasan teoritis. “Peran Bimbingan Belajar dalam Meningkatkan Motivasi Belajar dan Sikap Beragama Anak” merupakan sebuah teks konseptual. Dalam hal ini, bimbingan belajar dapat membangkitkan rasa ingin tahu anak-anak tentang pembelajaran dan memberikan peluang bagi mereka untuk memperoleh pengetahuan di luar kelas tradisional. Bimbingan belajar menjadi lebih informal dan menyenangkan ketika Anda menggunakan metode pengajaran interaktif, memasukkan materi yang segar atau menarik bagi mereka, dan membangun hubungan yang kuat dengan mereka. Selain itu, hal ini menunjukkan bagaimana memasukkan ide-ide keagamaan ke dalam kehidupan sehari-hari dapat menghasilkan transformasi positif.
Pengaruh Media Spining Whell terhadapKemampuan Berpikir Kritis Siswa Mata Pelajaran IPA Kelas V Sekolah Dasar
Authors: Nurhalijah Nurhalijah , Pratiwi Indah
Published: April 2024

Penelitian ini bertujuan untuk mengetahui Media Pembelajaran Spinning Wheel Terhadap Kemampuan Berpikir Kritis Siswa Mata Pelajaran IPA kelas V SD Pertiwi Medan. Penelitian ini dilatar belakangi dengan kegiatan awal yang dilakukan oleh peneliti yaitu wawancara dengan guru kelas V SD Pertiwi Medan, yang menyatakan bahwa masih terdapat beberapa siswa yang berada dibawah Kriteria Ketentuan Minimal (KKM). Penelitian ini dilaksanakan dari bulan Januari sampai bulan Februari tahun 2024. Penelitian ini termasuk jenis penelitian kuantitatif dengan menggunakan instrumen penelitian berupa tes, yakni one group Pretest-Posttest design, yaitu penelitian eksperimen yang dilakukan untuk satu kelompok saja. Design penelitian ini diukur dengan menggunakan pretest yang dilakukan sebelum diberi perlakuan dan postest setelah dilakukan perlakuan. hasil uji t yang menunjukan hasil signifikansi sebesar 0,000 yang dimana lebih kecil dari 0.05. Dengan demikian H0 ditolak dan Ha diterima. hasil uji t yang menunjukan hasil signifikansi sebesar 0,000 yang dimana lebih kecil dari 0.05. Dengan demikian H0 ditolak dan Ha diterima. Berdasarkan hasil Uji tersebut maka dapat disimpulkan bahwa terdapat pengaruh penggunaan media Spinning Wheel (X1) terhadap Kemampuan Berpikir Krits Siswa (Y) pada Mata Pelajaran IPA.
Evaluasi SDM Kefarmasian dan Kebijakan dalam Pengelolaan Logistik Obat di Klinik X
Authors: Wisesa Afina , Wulandari Ratna Dwi , Tarigan Elizabeth Tasya Octavianes
Published: April 2024

Permasalahan kelangkaan obat dan penumpukan obat sangat berhubungan dengan manajemen logistik obat yang harus dilaksanakan sesuai dengan kebijakan. Data rekapitulasi pemakaian obat Klinik Kesehatan X menunjukkan bahwa terdapat kejadian stagnant obat sebesar 53,62% dan kejadian stockout obat sebesar 7,25% sepanjang tahun 2022. Penelitian ini bertujuan untuk menganalisis kesesuaian faktor Sumber Daya Manusia Kefarmasian dan kebijakan di Klinik Kesehatan X dalam proses pengelolaan obat dengan ketentuan Peraturan Menteri Kesehatan Nomor 34 Tahun 2021. Jenis penelitian ini adalah penelitian deskriptif evaluatif dengan desain cross sectional. Penelitian dilakukan dengan metode wawancara, kajian dokumen, dan observasi. Kebutuhan informasi didapatkan dari Unit Farmasi Klinik Kesehatan X. Hasil penelitian menunjukkan bahwa faktor SDM kefarmasian dan faktor kebijakan atau Standar Prosedur Operasional (SPO) terkait proses pengelolaan logistik obat di Klinik Kesehatan X sudah sesuai dengan Peraturan Menteri Kesehatan Nomor 34 Tahun 2021 dengan persentase kesesuaian masing-masing sebesar 75% dan 88,89%. Meskipun persentase kesesuaian faktor SDM Kefarmasian dan faktor kebijakan sudah >50%, tetapi masih perlu adanya evaluasi untuk meningkatkan kesesuaian hingga mencapai 100%. Sehingga saran yang dapat diberikan adalah perlu adanya edukasi mengenai pemakaian tanda pengenal oleh seluruh tenaga kefarmasian dan penyusunan SPO Pemilihan Obat yang belum tersedia.
Peningkatan Kemampuan Menulis Teks Artikel dengan Model Pembelajaran Koperatif Group Investigation Pada Siswa Kelas XII
Authors: Arnesti Nosya Agretta , Charlina Charlina , Permatasari Silvia
Published: April 2024

Tujuan dari peneliaian ini adalah untuk mengetahui apakah terdapat peningkatan kemampuan menulis teks artikel pada siswa kelas XII SMAN 2 Selatpanjang setelah menggunakan model pembelajaran kooperatif group investigation. Penelitian ini menggunakan metode Penelitian Tindakan Kelas (PTK). Sumber data pada penelitian ini adalah siswa kelas XII MIA 2 SMA Negeri 2 Selatpanjang dengan jumlah siswa 34 orang. Teknik pengumpulan data pada penelitian ini adalah tes, observasi, dan wawancara. Instrumen dalam penelitian ini terbagi menjadi instrument tes dan penilaian hasil belajar siklus I dan siklus II, dan instrument non tes terdiri dari penilaian sikap dan penilaian proses belajar. Teknik analisis data dalam penelitian ini menggunakan teknik analisis data kuantitatif dengan menghitung rata-rata dan presentase. Hasil pada penelitian ini terlihat kemampuan menulis teks artikel mengalami peningkatan dari siklus I ke siklus II sejumlah 39%, pada siklus I nilai rata-rata siswa sejumlah 57,35 dan pada siklus II meningkat menjadi 96,18. Berdasarkan hasil tersebut pembelajaran teks artikel dengan menggunakan model pembelajaran kooperatif tipe group investigation memberikan perubahan positif pada siswa dengan peningkatan pada kemampuan menulis teks artikel.
Pre-donation Hydration and Muscle Tensing exercises to Reduce Donor adverse Reactions due to Blood Donation.
Authors: Shivamurthy Veena , Chandrasekhar Thotadamane , Ghatapanadi Shweta , LalyaNaik Pradeep , Samyuktha Kalagara , Girish Namratha
Published: April 2024

Introduction:
Blood Donors are the backbone of a Blood Transfusion service.Since blood donors are considerate volunteers, they should be encouraged , motivated and should be safe without any adverse reactions. As the quote says , people who have not donated have never been asked for .Post donation well being and donors being fine fettle will definitely have implications on blood donor return rate .voluntary repeat donations should be encouraged. If the donors are ensured of a pleasant experience, they will be motivated to become regular repeat donors. This can be accomplished by preventing adverse reactions during and post donation.

Objectives:
1.To study the frequency of occurrence of adverse reactions in voluntary whole blood donors.
2. To evaluate the efficacy of pre dontion hydration and muscle tensing exercises in preventing Adverse donar reactions
3. To look for associated factors like age, sex,mental status in the causation of donor adverse reactions

Methodology:
Study duration : 3 months .
Total of 800 donors will be included in the present study , of which 200 will in the standard group and 600 ( 200 each) in intervention group.
Randomly donors were assigned to one of four groups:
1) standard donation,
2) Leg exercise prior to Donation (venipuncture/Phlebotomy)
3) Pre-donation water (500 ml of bottled water consumed 20 to 30 minutes before donation),
4) Pre-donation water combined with leg exercise during donation
Statistical analysis:
Analysis :using SPSS 19.0 software.
All data will be entered in Excel and further analysed.
Results :
There was significant reduction in the VVR in group 3 and 4 when compared to group 1 and 2.Anxiety was more in group 1 and 2.we found that pre donation exercise was not acceptable/ tolerated by many donors and they became more restless / showed anxiety when compared to group 3 .there was no much difference between group 3 and group 4 with respect to VVR.Pre donation hydration and muscle exercise were associated with significantly lower VVR.
Implications :
Pre Donation Hydration ( 500 ml of water 15 to 20 minute before donating) and leg exercises will help reduce vasovagal reactions specially in Novice donors, thus adding them to the Donor Pool.
Hilights :
Pre donation Hydration and Muscle tensing exercise to reduce the Adverse donor reactions
Increase the Donor Pool

Key words : Predonation Hydration, Muscle tensing exercise, donor adverse reaction.
Post-Stroke Range of Motion Measurement Tool with Black Box Boundary Value Analysis Testing
Authors: Mustafa Lis , Prasetyo Yoyok , Syirajuddin M , Junus M , F Alvindha , J Wilda
Published: April 2024

Stroke is the second cause of death and the third cause of disability in the world. One of the treatments for post-stroke patients is physiotherapy. This treatment is expensive and requires mobility. Additionally, the level of adherence of post-stroke patients in carrying out physiotherapy also influences the effectiveness of healing. Therefore, this research proposes a new tool - named “the Post-Stroke Range of Motion (ROM) Measurement Tool with Black Box Boundary Value Analysis Testing – for physiotherapy telemonitoring of post stroke patients. This tool is designed on the left hand for measuring the ROM with the integration of MPU6050, MAX30102, and Flex sensors connected to ESP WROOM 32. This study uses a quantitative research type with a laboratory and field experimental method approach. The flex sensor was tested by measuring the minimum and maximum resistance values, which are converted into straight (0<11), bending (11<46), and fully bending (46<90), and the software was tested using the Black Box Boundary Value Analysis method. The outcomes unveil that the proposed system - with its various features - has the potential to be widely applied, and readily utilized by patients in physiotherapy rehabilitation exercise at home.
Course of COVID-19 in patients carrying different MEFV mutations of familial Mediterranean fever
Authors: Demir Bilgehan , Karahan Dogu
Published: April 2024

Familial Mediterranean Fever (FMF) is a genetic auto-inflammatory disease. Mutations in the Mediterranean fever (MEFV) gene cause inappropriate immune system triggering, leading to inflammatory episodes in the peritoneum, pleura, and joints. In the severe Coronavirus disease-19 (COVID-19) picture, the hyperimmune response and inflammatory process develop with exacerbation of the clinical condition. FMF disease, the drugs used in its treatment, and the possible effects of different genetic MEFV mutations on the course of COVID-19 arouse interest. In this study, 158 FMF patients with different MEFV gene mutations were evaluated using an online survey method in terms of COVID-19 course, hospitalization, additional comorbidities, and COVID-19 vaccination status. Participants were asked 21 questions and the data provided were compared between FMF MEFV gene mutations. 104 out of 158 cases did not get COVID-19. 9 of 54 cases who got COVID-19 were hospitalized. No statistically significant difference was found between MEFV gene mutations when evaluated and compared in terms of susceptibility to COVID-19, vaccination status, and presence of additional chronic diseases and comorbidities. The present study provides guidance on the role of FMF genetic mutations in the course of COVID-19. Our study may suggest that FMF MEFV gene mutations do not have a protective role against COVID-19. The results also may suggest that, as an inverse effect, MEFV gene mutations do not increase the risk of hyper-immune response and severe acute respiratory syndrome (SARS), which play a role in the severe course of COVID-19.
PECULIARITIES OF THE VERB IN KAZAKH, RUSSIAN AND ENGLISH LANGUAGES
Authors: Kuzembayeva A. M. , Dyusembayeva Zh. E. , Malyshev A. V. , Silantyeva Ye. V.
Published: April 2024

The article deals with the peculiarities of the verb in three languages: Kazakh, Russian, and English. The authors identify similarities and differences in the forms, conjugation, and use of verbs in Kazakh, Russian, and English. The authors conclude that the differences in verb forms reflect the cultural and linguistic peculiarities of each language, based on a comparative analysis.
APPROACHES TO THE CREATION OF NEOLOGISMS IN THE FIELD OF INFORMATION TECHNOLOGY
Authors: Aubakirova B. K. , Abilmazhinova B. Zh. , Kadyrov Zh. T.
Published: April 2024

The article considered the nature of the natural laws of new words in the field of language, which are constantly emerging and gradually coming out of the process of use. In connection with these changes, the relevance of the process of determining the nominative name of new concepts that have arisen arises. As a result of the development of information technologies, new forms of communication activity have been created. It is known that as a result of changes in communication activity, the sharp emergence of problems of creating a new word due to trends is a natural process. The rapidly developing social environment, continuous changes and innovations in the scientific and technological direction have a powerful impact on the language sphere. In this regard, the vocabulary of the language is constantly being intensively replenished with new elements. The regularity of the emergence and formation of a new concept in the language was considered from the point of view of the functional aspect of the language in modern society. Here it was envisaged to reveal the main problem of neologism - the emergence of new words, ways to recognize their meanings, priority areas for determining their functional function. In accordance with the pragmatic needs of society, they were differentiated based on the analysis of the factors that influenced their appearance, methods of using new words, and the study of models of formation. The linguistic nature of communication implemented through a computer was considered. The original causes of anglicisms, which have been adapted and are officially included in the vocabulary, a theoretical review of the works of domestic and foreign scientists was carried out and definitions were given from a scientific point of view.
USE OF PHRASEOLOGISTS IN THE WORKS OF ORALKHAN BOKEY
Authors: Esmatova M. T. , Zeylova M. Sh.
Published: April 2024

This article examines set expressions found in Oralkhan Bokey’s work “Atau Kere”. The concept of phraseological units has been deeply studied and its features have been identified. At the same time, the meanings of set expressions are revealed, and the features characteristic of phraseological phrases are shown. The meanings of popular and original phraseological units, their use are compared and revealed, and specific features characteristic of phraseological units are indicated. According to scientists, it has been proven that phraseology is a ready-made tool in the language.
ARTISTIC FEATURES OF ZHANAT ASKERBEKOVNA'S POETRY
Authors: Kadyrov Zh. T. , Koshanova Zh. T. , Berdimurat K.
Published: April 2024

The article scientifically examines the artistic features of the poetry o f akyn - Zhanat Askerbekovna, who came to the world of Kazakh poetry in the mid-80s. The personal writing style of Zhanat Askerbekovna and the news that led to the art of writing poetry are analyzed. The themes and main ideas of the poet's poems are determined. The themes of Zhanat Askerbekovna's poems are reflected in her native land, nature, family, historical poems and groups "Kultegnin mourning Bilge Kagan", "kustik birgen kerimsal", etc., and the features of the use of artistic means are described. The poetic character of folklore and mythological elements in the works of a master of words and a qualified teacher is differentiated, the order of use and meaning are determined. In the work of Zhanat Askerbekovna, cultural and national values are studied, and a final thought is expressed about the contribution to the development of Kazakh poetic art.
THE ISSUE STATUS OF CREATING ELECTRONIC HERBARIUM IN KAZAKHSTAN
Authors: Romanchuk V. V. , Madieva A. N. , Tleubergenova G. S.
Published: April 2024

Modern science is dynamically developing, the integration of information technology into other scientific fields is observed everywhere. These innovations have touched the herbarium field as well. Digital technologies open new directions for the work of Herbaria. The article shows the relevance of digitisation of botanical collections and the creation of a database of electronic herbarium. The review of Kazakhstan institutions carrying out activities in this direction is given. The main problems are outlined, successful solution of which will allow to succeed in creating a virtual herbarium in the country.
TRENDS AND PROSPECTS OF TRADE AND ECONOMIC COOPERATION BETWEEN KAZAKHSTAN AND ITALY
Authors: Nursultanova L. N. , Bokayeva A. K. , Kasymova A. K.
Published: April 2024

The article discusses the main directions of strategic cooperation between the Republic of Kazakhstan and the Italian Republic in the trade and economic fields. It is emphasized that the strategic partnership between the two countries is based on a solid foundation, and mutually beneficial relations with the Italian Republic, which is the third largest economy in the eurozone, has become a priority of the foreign policy of the Republic of Kazakhstan. In August 1992, an agreement was signed between the Italian Republic and the Republic of Kazakhstan to establish diplomatic relations. In 2007 the Business Council of Kazakhstan and Italy was created, the Intergovernmental Working Group on Industrial and Economic Cooperation and Exchange also operates.During this period the two states were able to raise the level of bilateral relations to a strategic partnership, went through formation, development and transformation and are looking for reserves to continue effective multilateral cooperation. The need for research is due to a number of factors. Firstly, for Italy, as a country with an open economy, the market of Kazakhstan and Central Asia is an important platform for promoting its goods and services. Secondly, establishing multilateral relations between the two countries is in the interests o f both the European Union and the Eurasian integration. Thirdly, the participation of Italy and Kazakhstan in achieving common goals on the world stage within the UN and the OSCE contributes to an understanding of the goals of foreign policy and constructive dialogue. Kazakhstan is interested in Italy’s experience in the development of small and medium-sized enterprises; we are talking about combining efforts in creating new enterprises in various fields.The relevance of the article lies in the fact that Kazakhstan and Italy build their relations on alliance and respect for national interests and understand the importance of strategic interaction, which will only increase in connection with the integration processes taking place in Europe and the Eurasian space. Today large-scale political transformations are being carried out in Kazakhstan. The Head of our state has proposed a program of reforms aimed at modernizing the political system, improving mechanisms for protecting human rights, and building a New Kazakhstan. In this context the dynamic relationship with the Italian Republic makes an important contribution to the implementation and promotion of the reforms carried out in our country.Kazakhstan intends to continue to pursue a foreign policy aimed at comprehensively strengthening and developing the strategic partnership with Italy.
INTEGRATION OF KAZAKH NOBILITY INTO THE ADMINISTRATIVE SYSTEM OF THE RUSSIAN EMPIRE THROUGH THE EXAMPLE OF THE VALIKHANOV
Authors: Abulgazina A. S.
Published: April 2024

This article is devoted to the processes of integration of Kazakh nobility into the administrative system of the Russian Empire during the accession of the Kazakh steppe to Russia. The process of integration of the Kazakh nobility into the administrative system of the Russian Empire was considered on the example of the family of Ch.Ch. Valikhanov, namely his great-grandfather Ablai Khan, grandfather Vali-khan and father Chingis. In this regard, two chronological stages of the process of colonization of the Kazakh steppe by the Russian Empire were identified. In accordance with the set task, the influence of the processes of integration of the Kazakh nobility into the administrative system of Russia on the change in the social structure of Kazakh society, which consisted in the formation of a new class group of officialdom, was revealed.
FOREIGN EXPERIENCE IN LEGAL REGULATION OF THE USE OF CRYPTOCURRENCY AS A MEANS OF PAYMENT
Authors: Mogunova M. M. , Shut O. A.
Published: April 2024

This article is devoted to the study of foreign experience in the legal regulation of cryptocurrencies, comparing their status by studying the experience of countries such as China, India, Japan, Venezuela. Cryptocurrencies have seriously affected the world since their appearance. States reacted differently to their appearance. Countries such as India or China, having banned them at the legislative level, have come to the gradual adoption and attempts to create their own, state-owned cryptocurrency. Venezuela, making an attempt to keep up with the times, has provided a project of its own, state-supported cryptocurrency. Consequently, they began to be able to control the process of cryptocurrency turnover, securing their status as a full-fledged means of payment at the legislative level. Many states have begun to consider cryptocurrencies as a commodity in order to be able to tax them with income tax.The relevance of this article is caused by the presence of some private law problems of regulating cryptocurrencies, which are discussed in this article. The article examines some legislative problems of using cryptocurrencies, and the impossibility of their regulation by states. In addition, the article emphasizes the need to create a single international standard for regulating cryptocurrencies, which would take into account the interests of all parties and ensure the security and transparency of operations with cryptocurrencies.
PENGARUH PEMBERIAN POSISI SEMI FOWLER TERHADAP PERUBAHAN TEKANAN DARAH PADA PASIEN CONGESTIVE HEART FAILURE
Authors: Neri Ervina Lili , Fauzan Suhaimi , Rahmah Gabby Novikadarti , Kahtan Muhammad Ibnu , Herman Herman
Published: April 2024

Latar Belakang: pasien Congestive Heart Failure (CHF) sering mengalami gangguan hemodinamik, salah satunya yaitu tekanan darah. Posisi semi fowler, dengan elevasi kepala tempat tidur sekitar 30 hingga 45 derajat, sering digunakan dalam praktik klinis untuk membantu mengelola kondisi tersebut. Meskipun posisi ini sering digunakan, perlu pemahaman yang lebih mendalam tentang dampaknya pada tekanan darah pasien CHF. Tujuan penelitian ini untuk mengetahui pengaruh pemberian posisi tidur semi fowler terhadap perubahan tekanan darah pada pasien CHF di ruang ICCU RS Tipe A di Kalimantan Barat. Metode: penelitian kuantitatif quasy experiment menggunakan desain non- equivalent control group pre-posttest design. Uji statistik yang digunakan adalah uji Wilcoxon dan uji Mann-Whitney. Jumlah sampel 32 orang terbagi menjadi 2 kelompok menggunakan purposive sampling. Instrumen penelitian yaitu tensimeter digital. Hasil: uji statistik Wilcoxon, pada kelompok intervensi nilai tekanan darah sistolik (TDS) dan diastolik (TDD) dari pretest ke posttest, tidak terjadi perbedaan yang signifikan p=0,856 (TDS) dan p=0,155 (TDD). Uji statistik Mann-Whitney, perubahan rerata TDS p=0,856 dan TDD p=0,155 secara statistik tidak bermakna. Begitu juga pada kelompok kontrol nilai rerata perubahan TDS p=0,190 dan TDD p=0,363 secara statistik tidak bermakna, (P < 0.005). Kesimpulan: penelitian ini menyimpulkan bahwa tidak ada pengaruh yang signifikan pemberian posisi semi fowler terhadap perubahan tekanan darah.
Kant'ın Eleştirel Felsefesi Üzerine Bir Soruşturma
Authors: Ortaoğlan Yıldırım
Published: April 2024

Bu çalışma, Kant’ın eleştirel felsefesinin temel kavramlarına odaklanmaktadır. Eleştiri kavramı, soruşturmanın merkezindedir. Bu merkez, bilgi yetilerimizin sınırlarını kuşatır. Sözü edilen kuşatıcılığın gölgesinde yapılması gereken, Kant’ın “eleştirel felsefesi” olarak tanımlanabilecek düşünce yolunun güzergâhlarını belirlemektir. Güzergâh, Kant’ın temel kavramlarının birer uğrak olarak ele alınmasını şart koşar. Böylesi bir koşul, bilinebilecek olanla bilinemeyecek olanın sınırlarını çizer. Kant’ın öznenin konumu sınır çizen düşünmesi ancak ve ancak eleştiri, akıl, a priori, a posteriori, deney, bilgi vs. kavramların birliğinde anlaşılabilir. Kant’ın bilginin kaynağı konusunda mesele ettiği kavramlar, hem onun modern düşünmede önemli bir kırılmanın eşiğinde durduğunu hem de yeni bir yolu nasıl açtığına yönelik bize bir izlek sunar. Söz konusu izleklerin bize sağladığı düşünme deneyimini takip etmek hem Kant’ın açtığı yolları keşfetmemizi sağlayacak hem de bilginin ve öznenin konumuna ilişkin eleştirel bir tutum elde etmek adına adım atmamızı kolaylaştıracaktır.
Uluslararası Risk Yönetişim Konseyi (IRGC) Risk Yönetişim Çerçevesi Bağlamında İklim Değişikliğinin Çevresel ve Güvenlik Çıktılarının Analizi: NATO Örneği
Authors: Özel Begüm , Yorulmaz Murat
Published: April 2024

Veriler, insana ait tüm yapıların korunması söz konusu olduğunda güvenliğin kritik bir konu olduğunu ortaya koymaktadır. Bu nedenle uluslararası anlamda felaketler, savaşlar ve karmaşık acil durumlar gibi geleneksel olguların yanı sıra iklim güvenliği gibi normatif olgular üzerinde de yoğunlaşılmaktadır. Sonuç olarak, politika yapıcıları en önemli iklim sorunlarının belirlenmesi ve ele alınması konusunda yardıma ihtiyaç duymaktadır. Sonuçlar, uluslararası kuruluşların dünya çapında iklimsel belirsizliklerle başa çıkmak için planlar oluşturmaya ve uygulamaya başladığını göstermektedir. Bu açıdan NATO’nun katkıları tartışılmayacak kadar yüksektir. Bugün NATO bu amaca ulaşmak için dünya çapındaki sistemsel değişime hem yapısal hem de işlevsel olarak uyum sağlamaktadır. Ayrıca NATO, Uluslararası Risk Yönetişim Konseyi (IRGC) Çerçevesini kullanarak iklim değişikliğiyle bağlantılı güvenlik tehditlerini belirlemiş ve bunlara karşı hazırlık yapmıştır. Her ne kadar NATO, iklim güvenliğine ilişkin ilk ilkeler dizisini oluşturmuş olsa da, iklim değişikliğinin müttefiklerin güvenliği üzerinde büyük etki yaratacak temel bir sorun olduğu yaygın olarak kabul edilmektedir. Bu bağlamda çalışmanın amacı, iklim değişikliğinin çevre ve güvenlik çıktılarını Kuzey Atlantik Antlaşması Örgütü'nün (NATO) risk yönetimi yaklaşımı açısından incelemektir.
PROMOVENDO A INCLUSÃO: DESAFIOS E OPORTUNIDADES NA EDUCAÇÃO E NA SOCIEDADE
Authors: Resende José Santana de , Santos Luana Gardene Pinto dos , Silva Ailça Barboza Gomes da , Silva Maria Sueli Soares da , Cruz Diomar Fé Santos da , Lameira Lanna Valėria da Costa , Pinheiro Conceição Viegas , Quaresma Mário Sérgio Baia , Cardoso Rosane do Socorro Pereira , Monteiro Maria Regina Agostinho , Benevides Silvana Ribeiro , Silva Girlene Amorim da
Published: April 2024

Este aborda a temática que aborda a importância de criar ambientes inclusivos tanto dentro das escolas quanto na sociedade em geral. Este tema ressalta a necessidade de reconhecer e celebrar a diversidade em todas as suas formas, incluindo diferenças culturais, étnicas, sociais, econômicas e de habilidades. No contexto educacional, isso envolve a implementação de práticas pedagógicas que atendam às necessidades individuais de todos os alunos, garantindo que cada um tenha acesso a uma educação de qualidade, independentemente de suas origens ou capacidades. No entanto, promover a inclusão não é isento de desafios. Questões como preconceito, discriminação, falta de recursos e falta de conscientização podem representar barreiras significativas para a criação de ambientes verdadeiramente inclusivos. Além disso, a inclusão não se limita ao ambiente escolar; ela também se estende à sociedade como um todo. Isso significa promover a acessibilidade em espaços públicos, garantir oportunidades iguais de emprego e participação cívica e combater o estigma em relação às diferenças. Apesar dos desafios, há também uma série de oportunidades que surgem quando a inclusão é priorizada. Uma sociedade inclusiva é mais rica culturalmente, mais inovadora e mais resiliente. A diversidade de perspectivas e experiências fortalece as comunidades e impulsiona o progresso social e econômico. Portanto, ao enfrentar os desafios da inclusão e aproveitar as oportunidades que ela oferece, podemos construir um mundo mais justo, equitativo e acolhedor para todos. Uma sociedade que inclui a todos é mais abundante em cultura, mais criativa e mais resistente. A variedade de pontos de vista e vivências enriquece as comunidades e impulsiona o avanço social e econômico. Assim, ao encarar os obstáculos da inclusão e usufruir das chances que ela proporciona, podemos edificar um ambiente mais justo, equânime e acolhedor para cada indivíduo.
EXPLORANDO O IMPACTO DAS FERRAMENTAS DIGITAIS NO POTENCIAL DO PROCESSO EDUCATIVO
Authors: Pelages Rodrigo Gonçalves , Santana Carlos Antônio Nunes , Rocha Luci , Domiciano Manoella Leandro Oliveira , Almeida Núbia Ponce Leão de Oliveira , Oliveira Romulo Farias de , Pinheiro Tânia da Silva , Pinheiro Telma da Silva , Santos Waneza Barroso dos
Published: April 2024

A inserção de ferramentas digitais no ambiente educacional representa uma mudança de paradigma, transformando a sala de aula em um espaço dinâmico e interativo que prepara os alunos para os desafios do mundo digitalizado. Essa integração oferece uma gama de benefícios, como o aumento da participação dos alunos, a personalização do ensino, o desenvolvimento de competências essenciais para o século XXI e a promoção da criatividade e da inovação. No entanto, a integração das ferramentas digitais também apresenta desafios que precisam ser superados. A falta de infraestrutura adequada em muitas escolas, a resistência de alguns professores à mudança e as questões de segurança e privacidade de dados dos alunos são alguns dos principais obstáculos. Para uma integração eficaz, é fundamental uma abordagem estratégica que considere as necessidades pedagógicas de cada contexto, a seleção criteriosa das ferramentas digitais mais adequadas e a formação contínua dos professores. A implementação de metodologias inovadoras e inclusivas, a adaptação das práticas educacionais e o diálogo constante entre todos os envolvidos no processo também são essenciais para o sucesso. Diversas ferramentas digitais podem ser utilizadas para enriquecer o ensino, como plataformas de aprendizagem online, aplicativos educacionais interativos, recursos de realidade virtual e aumentada, ambientes virtuais de aprendizagem e ferramentas de comunicação e colaboração. Essas ferramentas, quando utilizadas de forma adequada, podem promover um ensino mais envolvente, significativo e personalizado, preparando os alunos para os desafios do futuro. A integração das ferramentas digitais na educação é um processo contínuo que exige planejamento, investimento e compromisso de todos os envolvidos. Ao superarmos os desafios e aproveitarmos as oportunidades que essas ferramentas oferecem, podemos construir um futuro promissor para a educação, preparando os alunos para serem cidadãos críticos, criativos e inovadores na sociedade digitalizada do século XXI.