bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPLIKASI PENDIDIKAN YANG BERPUSAT PADA KRISTUS DALAM KELAS MATEMATIKA [THE IMPLICATIONS OF CHRIST-CENTER EDUCATION FOR MATHEMATICS CLASSES]
Authors: Saragih Melda Jaya , Hidayat Dylmoon , Tamba Kimura Patar
Published: June 2019

The purpose of education is to develop the potential of students to become human beings who believe and fear God Almighty, have noble character, are healthy, knowledgeable, capable, creative, independent, and become democratic and responsible citizens. But in practice, much education separates science and faith in God. Christian education allows students to get to know God more and develops the potential of each student according to God's truth and purpose. Mathematics learning should be a tool to bring students to see and admire God as the great Creator. Investigation and discovery in learning mathematics should acknowledge some of God's attributes and allow students to admire the beauty of mathematics and to praise God.

BAHASA INDONESIA ABSTRACT: Tujuan pendidikan adalah untuk mengembangkan potensi peserta didik agar menjadi manusia yang beriman dan bertakwa kepada Tuhan Yang Maha Esa, berakhlak mulia, sehat, berilmu, cakap, kreatif, mandiri, dan menjadi warga negara yang demokratis serta bertanggung jawab. Namun pada pelaksanaannya, banyak pendidikan memisahkan ilmu pengetahuan dan iman kepada Tuhan. Pendidikan Kristen membawa siswa untuk semakin mengenal Tuhan, mengembangkan potensi setiap peserta didik sesuai dengan kebenaran dan maksud Tuhan. Pembelajaran matematika seharusnya menjadi alat untuk membawa siswa semakin melihat dan mengagumi Allah sebagai Pencipta yang agung. Melalui investigasi dan penemuan dalam belajar matematika seharusnya menjadi pengakuan dari beberapa atribut Allah yang membawa siswa untuk mengagumi keindahan matematika dan membawa siswa untuk memuji Tuhan.

 
Exclusive graphs: a new link among labelings
Authors: Ichishima Rikio , Muntaner-Batle Francesc A. , Oshima Akito
Published: June 2019

In this paper, we define a strongly felicitous graph to be lower-exclusive, upper-exclusive and exclusive depending on different restrictions for the vertex labels. With these new concepts, we show that the union of finite collection of strongly felicitous graphs, a lower-exclusive one and an upper-exclusive one results in a strongly felicitous graph. We also introduce the concept of decompositional graphs. By means of this, we provide some results involving the cartesian products of exclusive graphs.
Implementation of super H-antimagic total graph on establishing stream cipher
Authors: Prihandoko Antonius Cahya , Dafik D. , Agustin Ika Hesti
Published: June 2019

This paper is aimed to study the use of super (a, d)-H antimagic total graph on generating encryption keys that can be used to establish a stream cipher. Methodology to achieve this goal was undertaken in three steps. First of all the existence of super (a, d)-H-antimagic total labeling was proven. At the second step, the algorithm for utilizing the labeling to construct a key stream was developed, and finally, the mechanism for applying the key to establish a stream cipher was constructed. As the result, according to the security analysis, it can be shown that the developed cryptographic system achieve a good security.
The oriented chromatic number of edge-amalgamation of cycle graph
Authors: Nurvazly Dina Eka , Manulang Jona Martinus , Sugeng Kiki A.
Published: June 2019

An oriented k − coloring of an oriented graph G⃗ is a partition of V(G⃗) into k color classes such that no two adjacent vertices belong to the same color class, and all the arcs linking the two color classes have the same direction. The oriented chromatic number of an oriented graph G⃗ is the minimum order of an oriented graph H⃗ to which G⃗ admits a homomorphism to H⃗. The oriented chromatic number of an undirected graph G is the maximum oriented chromatic number of all possible orientations of the graph G. In this paper, we show that every edge amalgamation of cycle graphs, which also known as a book graph, has oriented chromatic number less than or equal to six.
Chromatic Zagreb indices for graphical embodiment of colour clusters
Authors: Kok Johan , Naduvath Sudev , Jamil Muhammad Kamran
Published: June 2019

For a colour cluster C = (C1, C2, C3, …, Cℓ), where Ci is a colour class such that ∣Ci∣ = ri, a positive integer, we investigate two types of simple connected graph structures G1C, G2C which represent graphical embodiments of the colour cluster such that the chromatic numbers χ(G1C) = χ(G2C) = ℓ and $\min\{\varepsilon(G^{C}_1)\}=\min\{\varepsilon(G^{C}_2)\} =\sum\limits_{i=1}^{\ell}r_i-1$, and ɛ(G) is the size of a graph G. In this paper, we also discuss the chromatic Zagreb indices corresponding to G1C, G2C.
THE SHADOW ECONOMY IN THE EASTERN PARTNERSHIP COUNTRIES: MODELLING AND ESTIMATING IN THE CONTEXT OF THE NEEDS TO DEVELOP ECONOMIC COOPERATION BETWEEN THE EUROPEAN UNION AND EASTERN PARTNERSHIP COUNTRIES
Authors: Baneliene Ruta , Melnikas Borisas
Published: June 2019

The paper deals with a highly complicated problem related to the development of economic relations between the European Union and the so-called Eastern Partnership countries – Armenia, Azerbaijan, Belarus, Georgia, Moldova and Ukraine. The essence of the problem is the extremely excessive level of the shadow economy in the Eastern Partnership countries: the shadow economy considerably affects the situation in the Eastern Partnership countries and it causes in addition a profound negative impact on the economic cooperation with the European Union.
The assessment and monitoring of shifts in shadow economies in the Eastern Partnership countries is a crucial issue for the European Union, in particular to make responsible and reasoned policy decisions on the economic cooperation between the European Union and the Eastern Partnership countries. This fact leads to the needs to create and use adequate instruments for modelling and evaluating the shadow economy.
The opportunities of using various tools for modelling and evaluating the shadow economy are discussed herein.
The main focus of attention is directed to the new integrated approach to shadow economy modelling: this approach is distinguished by the fact that the shadow economy is analyzed and assessed in a holistic manner upon taking into account the different aspects of economic life and economic development processes. A new model applicable to the assessment of the shadow economy in the Eastern Partnership countries is described; this model is based on the idea of the so-called Tanzi model and was developed by covering the traditionally used independent variables such as taxes, wages and salaries, as well as the new modified indicators.
The paper describes empirical research on modelling and estimating of the scope and dynamics of the shadow economy in the Eastern Partnership countries, as well as the principal results of the said research. It has been shown that the shadow economy in the Eastern Partnership countries is highly, extensively and even dangerously developed. The results of the research show an existence of a link between the size of the shadow economy and the control of corruption, but this link is very diverse in different countries.
The methodological approach and research results presented in the paper can be used to create a decision support system for the development of the economic relations between the European Union and the Eastern Partnership countries.
Analysis of the Negative and Positive Impact of Institutional Factors on Unemployment in Visegrad Countries
Authors: Čermáková Klára , Jašová Emilie
Published: June 2019

The objective of our analysis is to associate V4 Member States indicators with the selected institutional factors of the labour market. In addition, it aims at extending the Sekhon’s standard model for inflation with institutional factors. For the purposes of estimating the NAIRU in V4 countries, we intend to use the Kalman filter method with a higher than common smoothing coefficient. The model’s data will produce a specific period in which the institutional factors actually have a negative effect or positive effect onto the unemployment rate in individual countries. Finally, the analysis of the character and intensity of the impact of institutional factors onto the unemployment rate in individual V4 countries should indicate space for a wider application of institutional characters by economic policymakers. They should be warned about the threat of overusing the institutional factors having a negative effect onto the development of both structural and cyclical unemployment.
A New Structural Analysis of Inflation and Economic Activity
Authors: Gao Jun , Zhu Sheng
Published: June 2019

We theoretically investigate the role of expectations in modelling economic activity and the evolution of inflation rates. The New Keynesian Phillips-IS model is extended in our study by having two types of firms with a fraction of firms that uses ‘limited’ information to develop their expectations. The remaining firms, which are referred to as forward-looking, would use all information available to set prices and make manufacturing budgets. Then we use UK data to examine the robustness of our extension. To estimate our augmented model, we employ the Uhlig (2005) priori restrictions and the Nakajima (2011a) time-varying parameter regression. Our results suggest that the expectations of each type of firms play an important role in explaining the inflation rate and real economic growth in the UK.
Financial Distress of Companies and Cash flow-Investment-Sensitivity: Evidence from Panel of Non-Financial Firms
Authors: Haque Abdul , Abid Ammar , Jibran Qamar Muhammad Ali , Asif Sohaib
Published: June 2019

This paper aims to investigate the effects of cash flow-investment sensitivity over firms facing varying levels of financial distress. For this purpose, cash flow, dividend policy, firm’s age, and size are used to create subsamples of firms facing different degrees of financial constraints. Using an unbalanced panel of 336 non-financial firms listed at Pakistan Stock Exchange over the period from 2006 to 2017, we provide evidence that the prevailing financial constraints affect the investment decisions of sample firms. Financial distress, as identified by cash flow, dividend policy and size of the firm, increases with the rise of cash flow-investment-sensitivity, thus substantiating the use of these measures as indicators of financial distress. Furthermore, evidence of the U-shaped investment curve is found when the sample is split on the basis of cash flow, suggesting a non-linear relation between cash flow and investment. The results shed light on the relation between financial and real cycle downturns suggesting the need for economic policies to be countercyclical with respect to financial and credit conditions.
THE EFFECT OF EXCHANGE RATE FLUCTUATIONS ON TRADE BALANCE OF PAKISTAN
Authors: Jadoon Arshad Ullah , Guang Yangda
Published: June 2019

This main goal of this study is to check the exchange rate fluctuations and its impact on trade balance in Pakistan. The annual time series data from 1971 to 2016 is used to check the short run and long run relationship between Exchange rate fluctuations trade balance of Pakistan. We employed the autoregressive distributed lag approach and results reveal that Exchange rate has positive and significant relationship with balance of trade in long run and short run. Devaluation of Pakistani rupees against USD, would increase the exports and ultimately trade balance will enhance. The inflation and money supply has negative and significant relationship with balance of trade in long run in Pakistan. The excess of money supply will increase inflation which reduces the exports and consequently, balance of trade would decrease. This study has a policy implications for government as well as local and foreign investors. The government should also play an important role to make such strategies which can increase the balance of trade in Pakistan and can boost the economic growth of Pakistan indirectly.
Conditional Dependence Structure in the Precious Metals Futures Market
Authors: Just Małgorzata , Łuczak Aleksandra , Kozera Agnieszka
Published: June 2019

The purpose of this paper was to assess the conditional dependence structure in the precious metals futures market in the period spanning from the beginning of 2000 to mid 2018. These time frames correspond to large fluctuations of quoted contract prices during the financial crisis. The dynamic Kendall’s tau coefficients and the dynamic tail dependence coefficients were used to assess the strength and dynamics of the nexus between rates of return on quoted prices of precious metals futures contracts. The coefficients were determined using the copula-based multivariate GARCH models, whereas the daily changes in the conditional dependence structure (changes in market state) were identified with the fuzzy c-means clustering method. In the study period, the conditional dependence structure in the precious metals futures market changed over time, as confirmed by the three identified market states. Of the contracts considered, gold and silver futures contracts demonstrated the strongest interrelationship and a relatively high likelihood of extreme events being transferred between them.
Women’s participation in the labor market and Economic Development: Evidence from ECCAS and ECOWAS Countries
Authors: Ouaïmon Ursula-Christiane , Zhang Yabin
Published: June 2019

This paper examines the relationship between women’s participation in the labor market and economic development in ECCAS and ECOWAS over the period 2006-2015 by using dynamic panel data model. The analysis is run from two different perspectives – on one hand, the relationship is investigated for a sample of 24 countries; and on the other hand – the evidence is disaggregated and the relationship is re-examined with two regional blocs (ECCAS, ECOWAS). The OLS, fixed effects model, instrumental IV and the generalized method of moments (GMM) estimator developed by Arellano and Bond (1991) are employed to evaluate and account for dynamic effects. The main results show that there is a U-shaped relationship between female labor force participation and the economic development for the encompassing 24 countries. The findings are important for ECCAS and ECOWAS countries policy makers to undertake effective policies that can boost female labor force participation and enhance economic growth in their countries.
ASSESSMENT OF WEALTH DIVERSITY (CASE OF LITHUANIA)
Authors: RAKAUSKIENĖ ONA GRAŽINA , SERVETKIENĖ VAIDA , VOLODZKIENĖ LINA
Published: June 2019

The high level of income and wealth distribution in the world is recognized as a phenomenon that leads to negative economic and social consequences. The imperfection of redistribution levers in the economy has created conditions for the concentration of resources, material goods and wealth in small population groups. Today, the economic system is not focused on majority of the population, and therefore the high level of inequality and its consequences for economic growth, well-being and human development cannot be ignored. In this context, too high economic inequality in Lithuania is one of the most sensitive problems of the country; Lithuania is an anti-leader in the European Union according to economic inequality.
Conventionally, economic inequality is measured using such methods as distribution of income and consumption of the population, however, to find out the real level of inequality, wealth diversity should be studied as well. The main purpose of this article is to identify and emphasise wealth diversity as an inseparable part of economic inequality in Lithuania and, as a result, the poor quality of life and obstacles in the way of economic progress as well as to compare wealth inequality with income inequality in Lithuania.
The authors organised a representative poll of Lithuanian citizens and used a certain survey to collect information about the dwelling-places or other types of assets owned by the respondents as well as to evaluate wealth diversity in the country. The results show that the edge value of the assets owned by the representatives between I and X deciles differs by 16.9 times. However, comparing the average prices of dwelling-places in deciles I and X, the difference amounts to 7.2 times. Assessing all types of assets, including accommodation, land, durable goods, etc., it has been revealed that the distribution of wealth exceeds the limit of income and consumption distribution established by various statistical organisations and by the authors themselves. The decile ratio (in relation to deciles I and X) equals to 40.8, thus, it considerably exceeds the level of income and consumption inequality.
Effect of NAFTA on Mexico´s wage inequality
Authors: Rodriguez-Villalobos Martha , Julián-Arias Antonio , Cruz-Montaño Alejandro
Published: June 2019

One of the benefits that the signing of the North American Free Trade Agreement (NAFTA) would bring to the country was the reduction of large differences in wages as a result of the increase in productivity. The present study measures the effect of demographic, labor, and sector variables on Mexico’s wage inequality during the period 1988 to 2017, as well as the impact that the incorporation to NAFTA has had. Through a fixed effects model, it was found that the increase in the proportion of people working in the service and agricultural sectors increased the wage gap, as well as the people who occupy managerial positions, since they obtained a relative salary higher than the average. Despite the expected results of NAFTA, this economic trade integration increased the wage differential in Mexico and these levels are invariant over time, giving way to proposals to change the minimum wage.
Efektivitas Buku Ajar Fisika Dasar 1 Berintegrasi Imtak dan Kearifan Lokal Melalui Model Pengajaran Langsung
Authors: Fitriah Lutfiyanti
Published: June 2019

Tujuan penelitian ini ialah mendeskripsikan efektivitas serta validitas dan kepraktisan penggunaan buku ajar Fisika Dasar 1 berintegrasi imtak dan kearifan lokal Kalimantan Selatan melalui model pengajaran langsung. Penelitian ini merupakan penelitian dan pengembangan, dengan model pengembangan Dick and Carey. Subjek ujicoba penelitian ini ialah 17 orang mahasiswa semester 1 Program Studi Tadris Fisika, Fakultas Tarbiyah dan Keguruan (FTK) UIN Antasari. Data diperoleh melalui lembar validasi, tes hasil belajar, dan angket. Data dianalisis secara kuantitatif dan kualitatif. Hasil penelitian menunjukkan bahwa efektivitas penggunaan buku ajar berkategori sedang dengan skor N-Gain sebesar 0,32; validitas buku ajar berupa isi, penyajian, dan bahasa berkategori sangat valid dengan kriteria validitas masing-masing aspek sebesar 93,75%; 92,36%; dan 95%.; dan kepraktisan buku ajar berkategori praktis dengan skor rata-rata 3,21. Simpulan penelitian ini menunjukkan bahwa buku ajar tersebut efektif digunakan dalam perkuliahan Fisika Dasar 1.The aim of this study is to describe the effectiveness and validity and practicality of the use of Basic Physics 1 textbooks with integrated faith and piety, and South Kalimantan local wisdom through the direct instruction model. This study is research and development, with the development model of Dick and Carey. The subjects of this study trial were 17 first-semester students in the Physics Tadris Study Program, Faculty of Tarbiyah and Teacher Training (FTK) of UIN Antasari. The data ware obtained through the validation sheet, the test of learning result, and questionnaire. The data are analyzed quantitatively and qualitatively. The result of the research shows the effectiveness of textbooks usage is medium category with the N-Gain score of 0.32, the textbooks validity of the content, the appearance, and the language have very valid category with the values are 93.75%; 92.36%; and 95%, and the practicability is practical with a mean score of 3.21. The conclusion of this research is the textbooks is effective to use in Basic Physics 1 lecture.
Penerapan Project Based Learning berbasis Alat Peraga Sederhana untuk Meningkatkan HOTS Peserta Didik
Authors: Sambite Febiyanti C.V , Mujasam Mujasami , Widyaningsih Sri Wahyu , Yusuf Irfan
Published: June 2019

Abstrak: Penelitian ini bertujuan untuk meningkatkan High Order Thinking Skill (HOTS) peserta didik melalui penerapan Project Based Learning (PjBL) berbasis alat peraga. Penelitian ini termasuk penelitian tindakan kelas mengacu pada model Kemmis dan Taggart dengan 2 siklus  yang terdiri dari tahap perencanaan, tindakan, pengamatan dan refleksi. Subjek penelitian adalah 14 peserta didik kelas X IPA salah satu SMA  di Manokwari Papua Barat. Instrumen yang digunakan adalah lembar observasi keterlaksanaan Rencana Pelaksanaan Pembelajaran (RPP) dan tes hasil belajar yang berisi soal HOTS. Hasil penelitian menunjukkan bahwa 1) keterlaksanaan RPP mengalami peningkatan, yaitu pada siklus I sebesar 50 dipertemuan I dan 60 dipertemuan kedua, menjadi  pada siklus II sebesar 61 dipertemuan I dan 66 dipertemuan kedua, dan 2) rerata nilai HOTS peserta didik mengalami peningkatan, yaitu pada siklus I sebesar 61,96 menjadi 71,49 pada siklus II. Ketuntasan klasikal mengalami peningkatan, yaitu pada siklus I 42,86% menjadi 71,43% pada siklus II.  Dengan demikian, penerapan PjBL mampu meningkatkan HOTS peserta didik Abstract: This study aims to improve the High Order Thinking Skill (HOTS) of students through the implementation of Project Based Learning (PjBL) based on props. This study included classroom action research referring to the Kemmis and Taggart models with 2 cycles consisting of the stages of planning, action, observation and reflection. The research subjects were 14 students of class X science in one of the high schools in Manokwari West Papua. The instruments used were observation sheets for the implementation of lesson plan and learning outcomes tests that contained HOTS questions. The results showed that 1) the implementation of the lesson plan increased, in the first cycle of 50 in the first and 60 in the second meeting, in the second cycle of 61 in the first meeting and 66 in the second meeting, and 2) the average value of the HOTS of students increased, at cycle I was 61.96 to 71.49 in cycle II. Classical completeness has increased, namely in the first cycle of 42.86% to 71.43% in the second cycle. Thus, the application of PjBL is able to increase HOTS of students
Effectiveness of Mobile Learning: moPhyDict to Improve High School Students’ Physics Conceptual Understanding
Authors: Polonia Betti Ses Eka , Yuliati Lia
Published: June 2019

In learning physics, the problem that arises is a lack of physics conceptual understanding in contextual learning. These problems are due to the absence of innovative and creative learning resources that can be used to learn by the students. One of the learning resources that can be used is a dictionary. moPhyDict (mobile physics dictionary) is a dictionary containing explanations of concepts and illustrations (images, videos, animations) in a language that is easily understood by students. This study specifically aims to test the effectiveness of Mobile Learning: moPhyDict to improve student’s physics conceptual understanding. The method employed in this study was a quasi-experiment design. The experimental design used a pretest-posttest control group design. The sample of the study was 60 students from senior High School, which divided into control group and experiment group. The instrument test in this study used conceptual multiple choice question. Based on the t-test on the control class and the experimental class, it can be inferred that there is a significance score of 0.031. These results are supported by data: (1) the average score of the ability to understand the concept of the control class who did not use moPhyDict increased from 37.4 to 55.46, and (2) the average score of the conceptual understanding of the experimental class who used moPhyDict increased from 40.87 to 74.33. It was concluded that moPhyDict is effective to improve physics conceptual understanding of High School Students.
The Just In Time Teaching: The Effect on Student Learning Achievements Viewed from Learning Motivation
Authors: Barikhlana Alvina , Sholikhan Sholikhan , Ayu Hena Dian , Jufriadi Akhmad
Published: June 2019

The purpose of this study is to determine the effect of Just In Time Teaching using schoology and learning motivation on students learning achievement. This research was conducted in Malang Middle School. The type of research is quantitative with quasi-experimental research design. The population of this study is VIII grade students; the sample of this study is class C and D each number bout 32 students. The sample was selected using a purposive sampling technique. Data collection techniques are collected by learning achievement tests and learning motivation observation sheets. Data analysis used by two-way ANOVA analysis. The results of the study indicate that; 1) There are differences in Physics learning achievement between students who learn in using the Schoology-based on Just In Time Teaching and students who learn in using conventional learning, 2) There are differences in Physics learning achievement between students who have high learning motivation and motivated students low learning, 3) There is no interaction effect using school-based on Just In Time Teaching with learning motivation towards learning achievement. It can be concluded that Just in Time Teaching can be one solution to increase student learning achievement. Students who learn with the Schoology-based on Just In Time Teaching and students who have high motivation can improve students learning achievement.
Feasibility of Learner Autonomy Oriented Physics Learning Material to Train Student’s Science Process Skills
Authors: Zakiati Elsa , Mastuang Mastuang , Suyidno Suyidno
Published: June 2019

Low level of student’s science process skills is due to the lack of use of experiments in learning. The study was conducted to produce learning materials which oriented to valid, practical, and effective learner autonomy; so that it is feasible to train student’ science process skills. The research uses the ADDIE development model design including Analyze, Design, Develop, Implement, and Evaluate. The research subjects were 30 students of class X B TKJ in one of vocational high school at Banjarmasin. The research instrument used a validation sheet, observation sheet from the lesson plan, observation sheet of science process skills, and test the learning outcomes of students. Further data were analyzed descriptively qualitatively and quantitatively. The results showed: 1) learning materials which oriented to learner autonomy were valid because the lessons plan, teaching material, student worksheet, and learning outcomes test were in the valid category, 2) learning materials which oriented to learner autonomy including practical because the component of lessons plans with direct instruction, guide inquiry and cooperative learning type group investigation in very practical categories, 3) learning materials which oriented to learner autonomy is effective because the cognitive N-gain tests are 0.51 in the medium category; 4) observations of science process skills in good categories and the result of N-gain science process skills tests are 0.76 in the high category. It can be concluded that the learning materials which oriented to learner autonomy were feasible to practice science process skills vocational high school’s students.
Increasing Students’ Activity and Learning Outcome Used Guided Discovery Model Assisted by PhET
Authors: Raihanah Siti , Susilowati Eko , Salam Abdul
Published: June 2019

The purpose of this study is to increase student's activity and learning outcome using guided discovery assisted by PhET (Physics Education Technology). The specific purpose of this study is to describe: 1) the implementation of the lesson plan, 2) activity, and 3) learning outcomes. The type of study that used is a classroom action research by Kemmis and Mc Taggart model that consists of two cycles. The subject of this study is the 24 students of class XII one of the vocational schools in the Banjarmasin city. The data is obtained through observation and test. The results of study in cycles I and II show: 1) the average score of implementation of the lesson plan increased from good category to very good category, 2) the student’s activity has increased 3) the learning outcomes increased from 0% to 87.5% and has been declared complete in cycle II. It can be concluded that the used implementation of guided discovery with PhET can increase activity and learning outcomes.
Molecular Identification of Cellulolytic Bacteria From Mangrove Sediment at Tin Minning Region In West Bangka
Authors: Kurniawan Ardiansyah , Sari Suci Puspita , Asriani Euis , Kurniawan Andi , Sambah Abu Bakar , Prihanto Asep Awaludin
Published: June 2019

Cellulose as an abundant source of glucose in Indonesia requires acceleration of decomposition utilizing cellulolytic bacteria.  Cellulolytic bacteria can be obtained from the isolation of mangrove organic matter, such as sediments. Muntok Sub-district is one of the regions with the most tin mining in West Bangka Regency also has mangroves in the coastal area. Exploration of cellulolytic bacteria in mangroves with different environmental characteristics encourages researchers to find new bacterial strains that produce cellulase enzymes with new properties. Thirteen isolates were successfully isolated from three locations. Tembelok mangrove sediments produced Seven bacterial isolates, Peltim Mangrove samples produced three isolates and from Sukal Mangrove three isolates were obtained. Seven isolates showed clear zones in the Lugol test and three isolates including were gram-positive bacteria. Molecular test with 16S rRNA analysis showed TBL1 isolate has 85% similar identity of  Vibrio parahaemolyticus strain HY3 and TBL2 isolate has 98% similar identity of Bacillus amyloliquefaciens strain HS8. Bacillus amyloliquefaciens potential to further study as cellulose degrading bacteria for feed ingredients.
The Use Extract of Siam Leaf Eupatorium odoratum L. as Alternative Material In Lowering Blood Glucose
Authors: Amaliah Ulfah Nur , Johannes Eva , Hasan Munif S , Tambaru Elis
Published: June 2019

The use of medicine as oral hypoglycemic and insulin have some limitation, the treatment for diabetics needs more expensive cost relatively because it uses in the long term and can give the unwanted  side effect. At the recent time, one of the conducted efforts is by using the plant as alternative medicine. This research aims to know the potential of leaves’ extract and to know the effectiveness of siam weed leaves extract’s dosage which most effectivein lowering the level of blood glucose in mice which is induced by alloxan. On this research, anti-diabetic effect of siam weed leaves was observed to male mice which had been induced by alloxan until the level of blood glucose >200 mg/dl. The given treatment orally was conducted during seven days with three variations of dosage concentration of infused extract, they are 5%, 10% and 20 %. Furthermore, it was also used the comparison i.e. infused extract of cinnamon bark with 10 % concentration. Data analyse used SPSS 23.0 program with one way ANOVA then was continued by using Duncan test. The research result shows that the siam weed leaves extract with dosage concentration 5%, 10% and 20% can decrease blood glucose level on mice that have suffered hyperglycemia and most effective on 20%. Thus, it can be concluded that siam weed leaves extract have the potential in lowering blood glucose.
Performance Assessment of Public Health Center Madising Na Mario Parepare, South Sulawesi, Indonesia
Authors: Pythaloka Ajeng Dyah , Abadi Muhammad Yusri , Darmawansyah Darmawansyah
Published: June 2019

Implement health efforts both public health efforts are first rate and first rate individual health efforts are needed health center management be integrated and continuous in order to produce the performance of Public Health Center effective and efficient. This study aims to find out about the picture of the level of achievement of performance results pertaining to quality health center health center services, management of health centers and health care Public Health Center Madising Na Mario Pare-pare. This research method is quantitative descriptive method, whereby it purports to describe the level of achievement of the performance results of health centers. From the research achievement of quality performance owned health center services obtained an average value of 9,7 performance with good performance categories. Public Health Center management obtained an average performance score of 10 with a good performance categories. Health services obtained the value of the average performance of 70,9% with less performance categories. Therefore, efforts to improve the performance of health centers needed professional human resources and improvement of health facilities, especially the budget required.
Study of Several Stages of Maturity and Storage Temperature on Color Changes and Shelf Life of Mangosteen (Garcinia mangostana L.)
Authors: Sumiasih Inanpi Hidayati , Poerwanto Roedhy , Efendi Darda
Published: June 2019

Color and freshness of mangosteen are important characters as benchmarks for consumers in the selection and purchase of mangosteen in the market. Color, freshness and shelf life of mangosteen are affected by the stage of maturity at harvest and the correct storage temperature. Information about the correct maturity stage for harvesting and storage temperature of mangosteen are needed by the mangosteen farmers, local merchant, and exporters as an effort to maintain the quality of fresh product. The objective of this research was to study the effect of several maturity stage at harvest and storage temperature to mangosteen color changes and shelf life during storage. The research used Completely Randomized Design of two factors. The first factor was the fruit maturity stage at harvest consisting of: Maturity Stage 1, 2, 3 and 4. The second factor was storage temperature of 15 oC and room temperature. The result of harvesting mangosteen at Maturity Stage 1 could maintain skin color longer than at Maturity Stage 2, 3, and 4. Mangosteens that were harvested at Maturity Stage 1 and 2, combined with storage temperature of 15 oC could maintain fruit quality up to 30 days after harvest and could be used for export market. While harvesting at Maturity Stage 3 could maintain fruit quality up to 25 days after harvest and Maturity Stage 4 up to 20 days after harvest. Harvesting at Maturity Stage 4 followed by 15 oC storage temperature and all Maturity stages combined with room temperature storage could be used for local market.Keyword: fruit color; horticultural commodities; queen of tropical fruits; shelf life
INHIBITION OF JUICE KOMBA-KOMBA (Chromolaenaodorata) LEAF AGAINST GROWTH OF BACTERIA Staphylococcus aureus
Authors: Yunus Reni , Hilam Muhammad , Darmayani Satya
Published: June 2019

Nowadays many plants can be used as traditional medicines to overcome various diseases including infections, because the use of traditional medicines is relatively safer compared to drugs derived from chemicals. One of the local plants in Southeast Sulawesi that has been empirically used as a medicine for wounds is a race of plants. Komba-komba leaves (Chromolaena odorata) containcompounds alkaloid, flavonoids, tannins, phenols, triterpenoids, saponins and steroids which have their respective functions in inhibiting the growth of microorganisms or antibacterial. This study aims to determine the inhibition of komba-komba leaf extract (Chromolaena odorata) on the growth ofbacteria Staphylococcus aureus. This type of research is experimental laboratories. The method used was agar diffusion with 5 treatment concentrations, namely komba-sheep leaf extract concentration (Chromolaena odorata) 20%, 40%, 60%, 80% and 100%, positive control (tetracycline) and negative control (aquadest) and repetition . The results showed that there was a inhibition zone of komba-komba leaf extract (Chromolaena odorata) on the growth ofbacteria Staphylococcus aureus at a concentration of 20% at 2 mm, a concentration of 40% at 3.7 mm, a concentration of 60% at 4.7 mm, a concentration of 80% 6.2 mm and a concentration of 100% by 8 mm.
Lectin Protein Spodoptera litura Activity After Exposured by Biopesticide from Mirabilis jalapa
Authors: Maulina Dina , Sumitro Sutiman B , Amin Muhammad , Lestari Sri Rahayu
Published: June 2019

Spodoptera litura is folifagus agricultural pest with a tendency of resistance towards chemistry compound. This becomes a reason in the efforts to overcome it. The use of botanical material becomes one of the alternatives in controlling its population. The plant of Mirabilis jalapa has the active biopesticide compound that becomes its alternative prevention. This plant has the potential chemistry compound as biopesticide which works toward weakening immunity that is ended by the death of S. litura.  This research aims to analyze the existence of lectin protein as an indicator of immunity reaction’s activation Spodoptera litura after exposing biopesticide M. jalapa. Lectin test was conducted by using spot-test hemagglutination assay (HA) then was seen its speed forming of titer. The result of research shows that lectin was on the part of hemolimf S. litura supernatant. The result test shows that on the concentration 0.2% binding of lectin, carbohydrate and erythrocyte cells of vertebrate formed faster. The speed of titer forming was influenced by the number of hemosit. This is caused by immulectin receptors were on the cell’s surface. Therefore, exposing M. jalapa can induce lectin activation which functioned as the recognizing receptor of strange object which directly bound with carbohydrate related to the reaction of body immunity.Key words: biopesticide Mirabilis jalapa, lectin, immunity system, Spodoptera litura.
Effect of seedling age, seeding density and nitrogen fertilizer on growth and grain yield of rice (Oryza sativa L.)
Authors: Thapa Saroj , Thapa Khagendra , Shrestha Jiban , Chaudhary Amit
Published: June 2019

Rice (Oryza sativa L.) is first staple crop of Nepal. The national average yield of rice is less than its potential yield, for which poor agronomic management has been reported as the critical factor. Among various agro-management practices seedling age, seeding density and nitrogen rates significantly affect the growth and yield of rice. The lower seeding density produces the taller plant, more effective tiller, lower sterility and higher grain yield. On the other hand, seedling of older age from higher seeding density gives the lowest yield. Transplanting younger seedling with low seeding density and application of recommended dose of nitrogen gives a higher yield. This article summarizes various effects of seedling age, seeding density and nitrogen rates on plant height, number of effective tillers, number of filled grains, thousand grain weight and grain yield of rice. This information may be useful for maize growers and researchers.
HIDUP DI USIA LANJUT TETAP SEHAT, AKTIF DAN PRODUKTIF
Authors: Jayadi Tejo
Published: June 2019

Kesimpulan dari editorial ini adalah adanya pergeseran demografi usia karena peningkatan penduduk lanjut usia, menjadi perhatian khusus dan membutuhkan peran serta lembaga pemerintah dan swasta, masyarakat, keluarga dan tenaga kesehatan untuk melakukan peningkatan pelayanan kesehatan preventif, promotif dan kuratif terhadap lansia yang rentan mengalami multimorbidity yang diketahui didasari oleh proses multi patologi.
Interferon inductors in prevention and treatment of respiratory infections in children
Authors: Vakhitov H. M. , Pikuza O. I. , Vakhitova L. F. , Zakirova A. M. , Rizvanova F. F.
Published: June 2019

In this article topical issues in treatment of acute respiratory infections in children and place of both exogenous interferons and interferon inducer drugs in their treatment are reviewed, including mechanisms of action, advantages and disadvantages of their application, special features of use in children. The latest clinical and laboratory data on the efficacy meglumine acridone acetate use in this pathology are given here. Depletion of inflammatory manifestations, correction of immune system imbalance were observed, leading to reduction of symptoms severity and disease duration, which, along with the good tolerability of the drug allows us to recommend it for widespread use in children.
Improvement of therapy efficacy in children with atopic dermatitis due to emollient complex
Authors: Kamaev A. V. , Trusova O. V. , Butyrina U. A. , Makarova I. V.
Published: June 2019

Active studies of atopic dermatitis (AtD) have revealed new disease pathways and confirmed the complex treatment approach need, including different forms of emollients (creams and bath treatments). Study aim: to show effectiveness of locally produced moisturizing cream and bathing oil combination (Lipobase baby trademark) in the complex treatment of babies and toddlers with AtD.

Patients and methods. Thirty children (60% boys) aged from 6 to 36 months with mild/moderate AtD were included in open prospective non-comparative study 30 days long. Initial and after each 2 weeks SCORAD and dairies for 10 points skin itch and sleep disturbance scores, moisturizers consumption and adverse events were evaluated. Global evaluation of treatment effectiveness score were performed by patient’s doctor.

Results. Medium compliance for moisturizers consumption was 89.2% days. Medium SCORAD results decreased from visit 1 to 3: from 23.5±7.3 points to 18.7±4.9 points and to 14.6±3.1 points. After 2 weeks complex therapy including investigated moisturizers, medium day skin itch score was reduced from 6.4 to 3.6 points, also as sleep disturbance score from 2.6 to 1.2 points. Direct moderate correlation (r=0.64, p=0.012) was revealed between number of days without skin itch or sleep disturbance and compliance to moisturizers consumption. No any adverse event caused by investigated products was registered.

Conclusion. Inclusion of locally produced moisturizing cream and bathing oil (Lipobase baby trademark) in the complex AtD therapy improve the treatment efficacy.

Conflict of interest: Products of medical cosmetics for use in this Protocol are provided by the Pharmatek Company LLC. Representatives of the Company did not participate in the statistical processing, interpretation of the results and preparation of this publication.
Infantile cerebral palsy as a result of prenatal brain dysontogenesis
Authors: Salkov V. N. , Khudoerkov R. M.
Published: June 2019

Infantile cerebral palsy (cerebral palsy) is one of the most common diseases of the nervoussystem in children. The etiology of cerebral palsy may differ, but structural changes in the brain in children are similar, regardless of clinical form. The paper summarizes the results of the recent studies on structural changes in the brain due to cerebral palsy. The literature sources demonstrate that the term of etiological factors impact on the developing brain of the fetus determines the characteristics of brain damage and localization of the damage, as well as the nature of the response from the nervous system.
Anti-NMDAR autoimmune encephalitis in children and herpes simplex virus-1
Authors: Skripchenko E. Yu. , Zheleznikova G. F. , Skripchenko N. V. , Alekseeva L. A. , Surovtseva A. V.
Published: June 2019

The review focuses on autoimmune encephalitis with antibodies to NMDA receptors, previously unknown autoimmune disease of the central nervous system, described in 2007. Anti-NMDAR encephalitis develops in adults and children, due to the tumor process and without it, it is manifested by characteristic syndrome of neurological and mental disorders. The authors separate anti-NMDAR encephalitis, which develops after the resolution of encephalitis caused by the herpes simplex virus-1. They describe the clinical manifestations of anti-NMDAR encephalitis in children and the effectiveness of early immunotherapy. Perspectively they discuss the pathogenesis of the disease, as well as the connection of herpes simplex virus infection and the development of anti-NMDAR encephalitis.
Osteosarcoma – on the way to personalized therapy. Part II: personalized therapy of the future
Authors: Rykov M. Yu. , Sengapova E. R.
Published: June 2019

Bone sarcomas account for 7% in the structure of malignant tumors in children, osteosarcomas take 35–50% of them. A significant proportion of patients are diagnosed at the spread stages of the disease, dictating the need to search for new approachesto treatment. Herewith the optimal therapeutic strategy is unknown, the results of treatment of children remain unsatisfactory. Part II describes the achievements in the field of personalized therapy, illustrating the vector of development of the principles of treatment of such complex diseases, which were fatal for most patients a few years ago.
Prebiotic components of breast milk and the possibility of repeating their effects in infant formulas
Authors: Skidan I. N. , Gulyaev A. E. , Belmer S. V.
Published: June 2019

It is fundamental truth that breast milk is the best food for a newborn, providing it with energy, high-quality nutrients, as well as a large variety of biologically active components necessary for adequate physical and psychomotor development. Acting either as part of complex biological structures or separately, the breast milk components, including personalized microbial and immune, regulate morphogenesis at the molecular and cellular level, determine the metabolism nature, guide the development of mucosal immunity in the child’s body. It is impossible to identify any component of breast milk as the main component that determines its functional activity and provides the benefits of natural feeding. The purpose of this review is to describe the role of prebiotics in breast milk and infant formula for the formation and maintenance of a healthy baby intestinal microbiota, which is a key element in the formation of normal digestion, a functionally sound immune system and metabolism.
Perinatal cardiology: the present and the future. Part I: congenital heart disease
Authors: Bokerija E. L.
Published: June 2019

The article discussesthe currentstate of the care level for fetuses, newborns and children with congenital abnormalities of the cardiovascular system. There are considered the features of prenatal diagnostics of heart defects and aspects of the management of pregnancy and childbirth of women with the specified pathology in the fetus. The authors made the analysis of the existing problems in the diagnosis and treatment of congenital heart defects and heart rhythm disorders in children. The article substantiates the introduction of the perinatal cardiology concept and formulates the main issues to be solved at this stage of development.
Value of the natriuretic peptide level in diagnostics of newborns with heart failure
Authors: Maslennikova I. N. , Bokerija E. L. , Kazantseva I. A. , Ivanets T. Yu. , Degtyarev D. N.
Published: June 2019

The article contains the first-ever data on correlation of the level of N-terminal fragment of natriuretic peptide in the serum of fullterm newborns with circulatory failure and persistent pulmonary hypertension syndrome; while the N-terminal fragment of natriuretic peptide can serve as a marker of circulatory failure in newborns. The study demonstrates that the dynamics of this peptide allows us to evaluate the effectiveness of the therapy.