bluuebunny/crossref_metadata_2025 huggingface dataset:
Os terrenos tectonoestratigráficos do entorno da parte centro-norte do Cráton do São Francisco
Authors: Brito-Neves Benjamin Bley de , Santos Ticiano José Saraiva dos , Dantas Elton Luiz
Published: June 2023

Este trabalho foca a presença de terrenos tectonoestratigráficos proximais situados no entorno da porção centro norte do Cráton de São Francisco. Há casos onde o embasamento de alto grau destes terrenos estarem em visível continuidade física com o embasamento do cráton. Outras vezes estão separados, e em algumas vezes esta passagem/relação não pode ser vista por estar acobertada por sedimentos fanerozoicos. A hipótese de uma “descratonização” em processo foi levantada. Almeida (1981) que então imaginara um cráton maior, no passado geológico (chamou-o de “Cráton Paramirim”, que sofrera processo de descratonização de suas bordas, com o desgaste lateral (tectônico, erosional) e assim com diminuição drástica de suas dimensões originais . A ideia de destruição cratônica (metacratonização) voltou a ser levantada nos últimos anos (Dantas et al. ,2019), com bons argumentos mas não suficientes. Em todos os casos, a deformação brasiliana está presente e dirigida para o interior do cráton, atingindo-o e também as suas coberturas neoproterozoicas. Os terrenos tectonoestratigráficos são considerados como “nativos” ou pertencentes anteriormente ao craton que avizinham, (de acordo com Kearey & al.,2009) Assim sendo a história de uma metacratonização é parcialmente viável, mas precisa ser discutida em termos de forma, causa e tempo. Nem sempre temos processos e dados claros e indiscutíveis. Neste trabalho vamos considerar três áreas do domínio meridional da Província Borborema : a ) Sudeste o Piauí - Noroeste da Bahia- domínios das faixas de dobramento Rio Preto; b) Norte da Bahia até o lineamento Pernambuco- domínios do Sistema de Dobramentos Riacho do Pontal; c) Nordeste-Leste do Craton , do Lineamento Pernambuco até o paralelo de Aracajú, nos domínios do Sistema de Dobramentos Sergipano. Todas esta áreas foram percorridas mais de uma vez pelos autores, oferecendo-lhes temas chamativos para uma discussão. Problemas existem e serão discutidos à luz do nosso conhecimento atual
The grouping of industrial enterprises by capacity utilization rate and level of debts to banks (II Quarter of 2022)
Authors: Aukutsionek S. , Demina N. , Bashirova I. , Serzhantova T.
Published: June 2023

Russian industrial enterprises, examined by the «Russian Economic Barometer» are grouped according to two criteria: the level of capacity utilization rate, as well as the level of debts to banks. This grouping allows you to see how key characteristics of enterprises differ depending on how their production capacities are loaded and what level of debts to banks they have. Data are presented for the second quarter of 2022.
Pandemic restrictions are over: an overview of changes in the main economic indicators of enterprises. Part 2. Investment activity of enterprises and changes in the output structure
Authors: Batyaeva A.
Published: June 2023

The article considers several aspects of the investment activity of enterprises (the involvement of enterprises in investment activities, the effectiveness of investments, the payback period, the availability of investment loans, production and technological innovations and changes in the structure of output). The main goal is to compare various characteristics of the investment behavior of enterprises during the period of COVID restrictions with the situation before their introduction and immediately after their removal. Contrary to trendy expectations, COVID restrictions did not collapse the investment activity of the enterprises. At the first stage of the pandemic, it stabilized, and then began to growth. COVID had a smaller negative effect on the investment activity of industrial enterprises than the crises of 1998-1999, 2008-2009 and 2014-2015. During the period of restrictions, the effectiveness of investments turned out to be worse than at previous highs, but in general it corresponded to the level of long-term averages. Manufacturers traditionally face great difficulties in obtaining investment loans. In this regard, the isolation of enterprises from the banking sector was increasing during the COVID period, but this negative trend had been formed long before COVID.
REB’s Statistical Series: Surveys of Agricultural Enterprises
Authors: Aukutsionek S. , Batyaeva A. , Demina N. , Egorov A. , Matveev A.
Published: June 2023

The article presents unique data on the Russian agricultural sector, which has been gathered by the Russian Economic Barometer for more than 30 years. There is published statistics reflecting the attitude of the heads of agricultural enterprises towards the economic policy of the government. There are presented data revealing the degree of importance for the agricultural producers of various factors limiting production and capital investments.
Exploring the Impact of Annual Report Inquiries on Audit Risk - Based on the Perspective of Anchoring Effect
Authors: Zhang Xinyue , Zhou Jun
Published: June 2023

The assessment of material misstatement risk is a critical judgmental matter for CPAs, but the uncertainty and subjectivity of judgment lead to a qualitative description of risk evaluation. By sorting out the inquiry letters issued by stock exchanges to listed companies in recent years, constructing a material misstatement risk system using fault trees and quantifying them using fuzzy hierarchical synthesis analysis, this paper not only provides a new reference basis and new audit ideas for annual audits, but also helps CPAs to better identify and evaluate material misstatement risks and improve the effectiveness of audits during annual audits.
Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma
Authors: Fu Danqi , Yan Jingrui , Zhang Zhaoyu , Liu Yang , Ma Xiaoqing , Ding Jinsheng , Yang Shengyu , Zhao Ran , Chang Antao , Gao Chuntao , Liu Jing , Zhao Tiansuo , Wang Xiuchao , Huang Chongbiao , Gao Song , Ma Ying , Tang Bo , Feng Yukuan , Wang Hongwei , Hao Jihui
Published: June 2023

Objective: Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant gastrointestinal cancer with a 5-year survival rate of only 9%. Of PDAC patients, 15%-20% are eligible for radical surgery. Gemcitabine is an important chemotherapeutic agent for patients with PDAC; however, the efficacy of gemcitabine is limited due to resistance. Therefore, reducing gemcitabine resistance is essential for improving survival of patients with PDAC. Identifying the key target that determines gemcitabine resistance in PDAC and reversing gemcitabine resistance using target inhibitors in combination with gemcitabine are crucial steps in the quest to improve survival prognosis in patients with PDAC. Methods: We constructed a human genome-wide CRISPRa/dCas 9 overexpression library in PDAC cell lines to screen key targets of drug resistance based on sgRNA abundance and enrichment. Then, co-IP, ChIP, ChIP-seq, transcriptome sequencing, and qPCR were used to determine the specific mechanism by which phospholipase D1 (PLD1) confers resistance to gemcitabine. Results: PLD1 combines with nucleophosmin 1 (NPM1) and triggers NPM1 nuclear translocation, where NPM1 acts as a transcription factor to upregulate interleukin 7 receptor (IL7R) expression. Upon interleukin 7 (IL-7) binding, IL7R activates the JAK1/STAT5 signaling pathway to increase the expression of the anti-apoptotic protein, BCL-2, and induce gemcitabine resistance. The PLD1 inhibitor, Vu0155069, targets PLD1 to induce apoptosis in gemcitabine-resistant PDAC cells. Conclusions: PLD1 is an enzyme that has a critical role in PDAC-associated gemcitabine resistance through a non-enzymatic interaction with NPM1, further promoting the downstream JAK1/STAT5/Bcl-2 pathway. Inhibiting any of the participants of this pathway can increase gemcitabine sensitivity.
Women’s Rights, Peace, and Democracy
Authors: Sánchez Muñoz Cristina
Published: June 2023

This paper analyses the reformulations of citizenship, positive peace and democracy‎ of both contemporary feminist theory and the feminist movement. ‎In doing so, it will explain the interrelationship between the feminist movement‎ as a democratic movement and its proposals for reformulating concepts‎ and ideas that make up what we can call the “grammar of politics”. Following ‎Seyla Benhabib, the “democratic iterations” that have been achieved in the ‎framework of human rights will be presented, giving some examples at national‎ and international levels. Finally, the changes and challenges in women’s‎ demands for rights in current scenarios will be analysed.‎
The Therapeutic Potential of Herbal Remedies To Prevent Leuke-Mia Stem Cell Reprogramming in Acute Myeloid Leukemia
Authors: Park Moon Nyep
Published: June 2023

Acute myeloid leukemia (AML) is the most common and incurable leukemia subtype. Despite extensive research into the disease's intricate molecular mechanisms, AML have not yet identified effective treatments or expanded diagnostic or prognostic markers. The morphological, immunophenotypic, cytogenetic, biomolecular, and clinical characteristics of AML patients are extensive and complex. Leukemia stem cells (LSC) consist of hematopoietic stem cells (HSC) and cancer cells transformed by the complex, finely-tuned interaction that causes the complexity of AML. Microenvironmental regulation of LSC dormancy, its diagnostic and therapeutic implications for identifying and targeting LSCs due to their significance in the pathogenesis of AML were discussed in this review. It is essential to perceive the relationship between the niche for LSCs and HSC, which together cause the progression of AML. Notably, methylation is a well-known epigenetic change that is significant in AML, and our data also reveals that microRNAs are a unique factor for LSC. Furthermore, multiple-targeted approaches to reduce the risk of epigenetic factors, such as the administration of natural compounds for the elimination of local LSC, may prevent potentially fatal relapses. Furthermore, the survival analysis of overlapping genes revealed that specific targets had significant effects on the survival and prognosis of patients. We predicted that the multiple-targeted effects of herbal products on epigenetic modification are governed by different mechanisms in AML and prevent potentially fatal relapses. Thus, these strategies can facilitate the incorporation of herbal medicine and natural compounds into the advanced drug discovery and development processes enabled achievable by Network Pharmacology research.
Differences in the Tumor Molecular and Microenvironmental Land-Scape Between Early (Non-metastatic) and De Novo Metastatic Primary Luminal Breast Tumors
Authors: Lambrechts Yentl , Hatse Sigrid , Richard François , Boeckx Bram , Floris Giuseppe , Desmedt Christine , Smeets Ann , Neven Patrick , Lambrechts Diether , Wildiers Hans
Published: June 2023

Background. The molecular mechanisms underlying de novo metastasis of luminal breast cancer (dnMBC) remain largely unknown.
Materials & Methods. Newly diagnosed dnMBC patients (grade 2/3, ER+, PR+/-, HER2-), with available core needle biopsy (CNB), collected from the primary tumor, were selected from our clinical-pathological database. Tumors from dnMBC patients were 1:1 pairwise matched (n=32) to tumors from newly diagnosed patients who had no distant metastases at baseline (eBC group). RNA was extracted from 5 x 10µm sections of FFPE CNBs. RNA sequencing was performed using the Illumina platform. Differentially expressed genes (DEG)s were assessed using EdgeR, deconvolution was performed using CIBERSORTx to assess immune cell fractions. Paired Wilcoxon test was used to compare dnMBC and eBC groups, and corrected for false discovery rate (FDR).
Results. Many regulatory DEGs were significantly downregulated in dnMBC compared to eBC. Also, immune-related and hypoxia-related signatures were significantly upregulated. Paired Wilcoxon analysis showed that CCL17 and neutrophils fraction were significantly upregulated, whereas the memory B-cell fraction was significantly downregulated in the dnMBC group.
Conclusion. Primary luminal tumors of dnMBC patients display significant transcriptomic and immunological differences compared to comparable tumors from eBC patients.
Proline Enhances Resistance and Recovery of Oilseed Rape after a Simulated Prolonged Drought
Authors: Jurkonienė Sigita , Mackevičiūtė Rima , Gavelienė Virgilija , Šveikauskas Vaidevutis , Zareyan Mariam , Jankovska-Bortkevič Elžbieta , Jankauskienė Jurga , Žalnierius Tautvydas , Kozeko Liudmyla
Published: June 2023

This study was carried out to evaluate the effect of exogenous proline on growth, biochemical responses, and plant recovery of drought-stressed oilseed rape plants after renewed irrigation. The experiment was conducted under controlled laboratory conditions. After 21 days of cultivation, 3-4 leaf stage seedlings were sprayed with proline (1 mM), then subjected to prolonged drought stress for 8 days to achieve a severe water deficit, then irrigation was resumed and recovery was assessed after 4 days. The results show that exogenous application of proline reduced drought-induced growth inhibition of seedlings while maintaining relative water content (RWC) and growth parameters closer to those of irrigated plants. Proline had a positive effect on chlorophyll accumulation and membrane permeability while decreasing ethylene, H2O2, and MDA levels. Moreover, after 4 days of recovery, the H2O2 content of the proline-treated plants was significantly lower (2-fold) and the MDA content was close to that of continuously irrigated plants. Thus, all these biochemical reactions influenced plant survival: after drought + proline treatment, the number of surviving plants was 2 times higher than that of drought-treated plants. The findings show that exogenous proline has antioxidant, osmotic, and growth-promoting properties that improve the drought tolerance of winter oilseed rape plants and is, therefore, beneficial for drought adaptation in oilseed rape.
Post-Covid-19 Pandemic Era and Sustainable Healthcare: Organization and Delivery of Health Economics Research (Principles and Clinical Practice)
Authors: Heydari Mohammad , Lai Kin Keung
Published: June 2023

Health services research is a multidisciplinary discipline that aims to improve population health by studying healthcare services' organization, delivery, and financing. Over time, the field has worked to define its boundaries and establish a set of core research topics and methods addressing population wellbeing, access, quality, and cost. Although the influence of health technology is significant, our literature survey on health services research showed that SCs in general—containing their management, cost, and policy—had received little attention. Importantly, our assessment also showed that the system’s readiness to handle supply policy and supply device deficiencies like those encountered during pandemic was hardly ever mentioned. Reduced open areas and water bodies, deteriorating infrastructure, and changes in the biological morphology all affect cities’ uncontrollable and unplanned growth. Urban amenities, facilities, and healthcare services were unevenly distributed due to this unchecked urban population development. In light of this, this research suggests two reliable models for site selection issues for one of Hong Kong’s main hospitals. Levels of uncertainty, infeasibility tolerance, and reliability are taken into consideration. Then, two categories of uncertainty—symmetric and bound-ed—were examined. As a result, the challenge of scheduling in uncertainty has been considered, and potential solutions have been presented using a specified probability distribution function. The paper concludes by introducing the specific justice and health problems and outlining four typical strategies. In order to ensure that medications and other healthcare supplies are produced, distributed, and given to patients, a vast network of systems, components, and procedures must be effectively managed. This research contributes in this regard. Also, its grantee fairness in health systems and the populations health locally, nationally, and globally. It highlights health inequity, advances the measurement of health inequity, and promotes public dialogues on health inequity.
Deubiquitinase OTUD6A Regulates Innate Immune Response Via Targeting Ubc13
Authors: Li Zhiwei , Li Guanwen , Li Yunfei , Luo Yujie , Jiang Yuhan , Zhang Ziyu , Zhang Ziyi , Liu Shengde , Wu Chen , You Fuping
Published: June 2023

Abstract: OTUD6A is a deubiquitinase that plays crucial roles in various human diseases. However, the precise regulatory mechanism of OTUD6A remains unclear. In this study, we found that OTUD6A significantly inhibited the production of type I interferon. Consistently, peritoneal macrophages and bone marrow-derived macrophages from Otud6a-/- mice produced more type I interferon after virus infection compared to cells from WT mice. Otud6a-/- mice also exhibited increased resistance to lethal HSV-1 and VSV infections, as well as LPS attack due to decreased inflammatory responses. Mechanistically, mass spectrometry results revealed that UBC13 was an OTUD6A-interacting protein, and the interaction significantly enhanced after HSV-1 stimulation. Taken together, our findings suggest that OTUD6A plays a crucial role in the innate immune response and may serve as a potential therapeutic target for infectious disease.
Learning Data-Driven Stable Corrections of Dynamical Systems. Application to the Simulation of the Top-Oil Temperature Evolution of a Power Transformer
Authors: Ghnatios Chady , Kestelyn Xavier , Denis Guillaume , Champaney Victor , Chinesta Francisco
Published: June 2023

Many engineering systems are described by using differential models whose solutions, generally obtained after discretization, can exhibit a noticeable deviation with respect to the response of the physical systems that those models are expected to represent. In those circumstances one possibility consists of enriching the model in order to reproduce the physical system behavior. The present paper considers a dynamical system, and proposes enriching the model solution by learning the dynamical model of the gap between the system response and the model-based prediction, while ensuring that the time integration of the learnt model remains stable. The proposed methodology is applied on the simulation of the top-oil temperature evolution of a power transformer, whose data is provided by RTE, the French Electricity Transmission System Operator.
Hyperacusis in the Fmr1-KO Mouse Model of Fragile X Syn-drome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels
Authors: Ferraguto Celeste , Bouleau Yohan , Peineau Thibault , Dulon Didier , Pietropaolo Susanna
Published: June 2023

Hyperacusis, i.e., an increased sensitivity to sounds, is described in several neurodevelopmental disorders (NDDs), including Fragile X Syndrome (FXS). The mechanisms underlying hyperacusis in FXS are still largely unknown and effective therapies are lacking. Big conductance calci-um-activated potassium (BKCa) channels have been proposed as a therapeutic target to treat several behavioral disturbances in FXS preclinical models, but their role in mediating their au-ditory alterations has not been specifically addressed. Furthermore, studies on the acoustic phe-notypes of FXS animal models have mostly focused on central rather than peripheral auditory pathways. Here we provided an extensive characterization of the peripheral auditory phenotype of the Fmr1-knockout (KO) mouse model of FXS at adulthood. We also assessed whether the acute administration of Chlorzoxazone, a BKCa agonist, could rescue the auditory abnormalities of mutant mice. Fmr1-KO mice both at 3 and 6 months showed a hyperacusis-like startle pheno-type with paradoxically reduced auditory brainstem responses associated with a loss of ribbon synapses in the inner hair cells (IHCs). BKCa expression was markedly reduced in the IHCs of KO mice, but only at 6 months, when Chlorzoxazone rescued mutant auditory dysfunction. Our findings highlight the age-dependent and progressive contribution of peripheral mechanisms and BKCa channels to hyperacusis in FXS, suggesting a novel therapeutic target to treat auditory dysfunction in NDDs.
Diabetic Ketoacidosis in Children and Adolescents; Diagnostic and Therapeutic Pitfalls
Authors: Kostopoulou Eirini , Sinopidis Xenophon , Fouzas Sotirios , Gkentzi Despoina , Dassios Theodore , Roupakias Stylianos , Dimitriou Gabriel
Published: June 2023

DKA represents an acute, severe complication of relative insulin deficiency and a common presentation of Type 1 Diabetes Mellitus (T1DM) primarily and, occasionally, T2DM in children and adolescents. It is characterized by the biochemical triad of hyperglycaemia, ketonaemia and/or ketonuria, and acidaemia. Clinical symptoms include dehydration, tachypnoea, gastrointestinal symptoms, and reduced level of consciousness, precipitated by a variably long period of polyuria, polydipsia and weight loss. The present review aims to summarize potential pitfalls in the diagnosis and management of DKA. A literature review was conducted using the Pubmed/Medline databases including articles published from 2000 onwards. Diagnostic challenges include differentiating between T1DM and T2DM, DKA and hyperosmolar hyperglycaemic state (HHS), or between DKA and alternative diagnoses presenting with overlapping symptoms, such as pneumonia, asthma exacerbation, urinary tract infection, gastroenteritis, acute abdomen and central nervous system infection. The mainstays of DKA management include careful fluid resuscitation, timely intravenous insulin administration and restoration of shifting electrolyte disorders and underlying precipitating factors. However, evidence suggests that optimal treatment remains a therapeutic challenge. Accurate and rapid diagnosis, prompt intervention and meticulous monitoring are of major importance to break the vicious cycle of life-threatening events and prevent severe complications during this potentially fatal medical emergency.
Do Silicon and Salicylic Acid Attenuate Water Deficit Damage in Talisia esculenta Radlk. Seedlings?
Authors: Figueiredo Vanda Maria de Aquino , Scalon Silvana de Paula Quintão , Santos Cleberton Correia , Linné Jéssica Aline , Silvério Juliana Milene , Cerqueira Wállas Mattos , De Alemeida João Lucas Santos Costa
Published: June 2023

Water deficit is one of the factors that most influence plant growth and yield. Thus, this study aimed to evaluate the effect of silicon and salicylic acid application and water deficit on the growth and photosynthetic and osmoregulatory metabolism of Talisia esculenta Radlk seedlings and their recovery potential after the resumption of irrigation. Six treatments were performed: irrigation, irrigation suspension, irrigation suspension + silicon at 0.5 g L−1, irrigation suspension + silicon at 1.0 g L−1, irrigation suspension + salicylic acid at 50 mg L−1, and irrigation suspension + salicylic acid at 100 mg L−1. The evaluations were carried out at the beginning of the experiment (T0), at 10 and 15 (DIS) days after irrigation suspension, when the seedlings showed a photosynthetic rate close to zero, and at recovery (REC). The plants were submitted to water restriction for up to 15 days, being then re-irrigated until the recovery point, which was monitored based on the photosynthetic rate. Silicon application attenuated the harmful effects of water deficit on gas exchange, initial fluorescence, promoted proline accumulation in the leaf and root, and provided higher seedling quality. Salicylic acid application contributed to the maintenance of the relative water content of leaves during the water deficit period. Silicon and salicylic acid applications can attenuate the harmful effects of water stress, with silicon being the most effective agent in maintaining its growth and metabolism.
Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review
Authors: Muteeb Ghazala , Rehman Md Tabish , Shahwan Moayad , Aatif Mohammad
Published: June 2023

Antibiotic resistance has emerged as one of the major concerns to public human health due to issues in treatment and control of major infectious diseases. From discovery of penicillin in 1940, the antibiotic resistance originated and now developed the microorganisms as resistive strains to the major available antibiotics. Furthermore, studies on this captivating activity of the microbes provide insight into the complexities of microbial physiology and may offer some guidance in preventing the onset and consequent development of antibiotic resistance. Despite of initiatives taken in last few decades to overcome the issues, the trends of antibiotic resistance gained much peak. Antibiotic resistance appears to have emerged as a result of various factors including antibiotics being misused and overused in both the medical field and the agricultural sector. Important factors in the development of antibiotic resistance also include bacterial mutation, unplanned evolution, and horizontal gene transfers. In addition, antibiotics resistance imposed the financial consequences to public health and drug development research. Future advancements related to innovative antibiotics and molecular drug designing become challenge for researchers due to intensive multiple antibiotics resistance among human population. Many researches have been conducted on origin, evolutionary aspect of antibiotic resistance and mechanisms of antibiotics resistance, but its effect on future drug development is little understood. Therefore, the recent review will highlight the role of antibiotic resistance in drug designing and impacts of antibiotic resistance on drug development in future.
Regulation of Pol II Pausing During Daily Gene Transcription in the Mouse Liver
Authors: Xu Wei , Li Xiaodong
Published: June 2023

Cell autonomous circadian oscillation is present in central and various peripheral tissues. The intrinsic tissue clock and various extrinsic cues drive gene expression rhythms. Transcription regulation is thought to be the main driving force for gene rhythms. However, how transcription rhythms arise remains to be fully characterized, due to the fact that transcription is regulated at multiple steps. In particular, Pol II recruitment and pause release are two critical regulatory steps that determine the status of Pol II pausing. Recently, we showed that Pol II pausing exhibits genomewide changes during daily transcription in mouse liver. In this article, we review historical as well as recent findings on the regulation of transcription rhythms. We also discuss the possible mechanisms for daily changes in Pol II pausing and the critical involvement of Pol II pausing regulation in generating rhythmic transcription output.
Recycled Tire Fibers as Reinforcement for Recycled Polyethylene
Authors: Kazemi Hossein , Ira Jean-Phillippe , Fazli Ali , Rodrigue Denis
Published: June 2023

Recycled tire fibers (RTF) are currently one of the most abundant waste not being recovered due to several processing hurdles and the presence of high amounts of residual ground rubber particles (GR). Therefore, this study proposes a simple approach to separate most of rubber particles from fibers and to determine their rubber content using thermogravimetric analysis (TGA)/calcination. Afterwards, clean fiber (CF) and GR are used as fillers for recycled post-consumer low density polyethylene (rLDPE), and their effects on the physical properties are investigated. Accordingly, a series of composites with CF and GR is prepared at different filler concentrations (0-30%) via extrusion compounding before using compression molding and injection molding for comparison. In all cases, injection molding leads to higher strength and modulus, but lower elongation at break. The results show that incorporating 30 wt.% of CF into rLDPE yields a remarkable improvement in tensile strength (15%), tensile modulus (192%) and flexural modulus (142%). On the other hand, the incorporation of up to 30 wt.% of GR results in a reduction of both tensile strength and flexural modulus by 15%, confirming the critical role of the cleaning process for RTF in achieving the best results.
The Transformation of Coastal Governance Pattern from Human Ecology to Political Ecology—A Case Study of Jimei Peninsula, Xiamen, China
Authors: Zou Zhe , Zhang Yu-Yan , Lee Su-Hsin , Tsai Shu-Chen
Published: June 2023

The coastal zone, situated at the sensitive interface between land and sea, serves as a pivotal area of extensive human economic activities. As one of China's economic special zones, Xiamen exemplifies the comprehensive trajectory of coastal governance in China. This research adopts an interdisciplinary approach grounded in historical geography and political ecology, employing data collection methods encompassing historical literature, field surveys, and interviews. The research findings indicate that:(1) The year 1994 witnessed the pivotal role played by the United Nations Convention on the Law of the Sea (UNCLOS) in connecting Jimei Peninsula from a local context to the international arena, thus signifying a momentous turning point in the process of scale reconstruction. However, the subsequent implementation of the Coastal Exclusion Policy in 2002 had detrimental consequences, leading to the disintegration of the local scale, the erosion of maritime culture, and the disregard for the livelihood security of displaced coastal populations.(2)The Coastal Exclusion Policy serves as an instrumental tool for implementing scale politics, while its functional realignment has had profound implications for the coastal zone, encompassing economic transformation, ecological degradation, and the marginalization of the socio-cultural fabric that intertwines humans and the coastal environment.
FIRE PROTECTION IN RELIGIOUS MONUMENTS: ON THE EXAMPLE OF NOTRE-DAME DE PARIS AND THE CATHEDRAL OF ST. PETER AND ST. PAUL IN NANTES, FRANCE
Authors:   University of Ecology and Management, Warsaw. Poland Faculty of Architecture, Paszkowski Zbigniew W. , Balcerzak Magdalena ,   University of Ecology and Management, Warsaw. Poland Faculty of Architecture
Published: June 2023

The cases of the fires of Notre-Dame in Paris and St Peter and St Paul in Nantes present the effects of the gradual neglect of monument conservation and their impact on a decrease in safety. The causes and consequences of the fires were described. Differences in the methods of technical protection and reconstruction after a fire have been specified. It was reported that in the Cathedral in Nantes, the wooden truss was replaced with a concrete one, whereas in Notre-Dame the original truss will be recreated. The need to select fire protection and reconstruction methods on a case-bycase basis and use comprehensive fire-resistance systems was indicated.
THE FCM MODEL AS A METHOD OF PUBLIC SPACE MANAGEMENT
Authors:   Uniwersytet Zielonogórski, Poland Wydział Budownictwa, Architektury i Inżynerii Środowiska Instytut Architektury i Urbanistyki, Abramiuk Inna
Published: June 2023

The work presents the results of research that focus on creating high-quality public space through the involvement of society and taking into account the opinions of various stakeholder groups. The main goal is to understand how the concepts of "man-space-management" can be integrated in the process of creating high-quality public places in accordance with the principles of UN-Habitat. An important research aspect is the development of FCM (Fuzzy Cognitive Maps) models and various scenarios for the development of public space, which will enable the effective use of financial resources by the government, non-governmental organizations and private investors. The research is based on the opinions of the Zielona Góra community, which were collected through "placegame" workshops and questionnaires.
BIBLIOMETRICS AND SCIENTOMETRIC REVIEW: PERSPECTIVES AND DEVELOPMENTS IN THE USE OF GREEN ROOFS
Authors:   Uniwersytet Zielonogórski, Poland Wydział Budownictwa, Architektury i Inżynierii Środowiska Instytut Architektury i Urbanistyki, Rzeszowska Natalia
Published: June 2023

Green roofs are a multifunctional element of the building envelope, which, with appropriate modifications, can offer many benefits not only for its direct users, but also positively affect the environment around it. Global climate change and rapid urbanization have presented us with a number of urban challenges that negatively affect the physical and mental health of city dwellers. The subject of the article is to present the perspectives and main development trends in the use of green roofs in architecture. On the basis of the bibliometrics and scientometric analysis of the selected subject, the main research trends were presented, the countries contributing most to its development were distinguished, and the most influential authors were presented.
PECULIARITIES OF THE FORMATION OF THE MOORISH STILE IN YELISAVETGRAD (USING THE EXAMPLE OF THE BUILDINGS OF I. A. GOLDENBERG'S WATER CLINIC AND THE CHORAL SINAGOGE)
Authors:   Kropyvnytskyi Ukraine, Penyaz Tetyana , Slєptsov Oleg ,   Head of Department of Fundamentals of Architecture and Architectural Design, Kyiv National University of Construction and Architecture. Ukraine
Published: June 2023

The article analyses the peculiarities of the application of elements of Moorish architecture on the example of two buildings built in the town Kropyvnytsky (Yelysavetgrad) at the end of the 19th and the beginning of the 20th century. During the twentieth century, the architecture of the historysm (eclecticism) received little attention because it was considered to be imitative, it was not distinguished by clearly defined compositional and stylistic methods. Since the end of the 20th century, with the development of the postmodern paradigm, the principles of the formation and application of stylistic features of the styles of past eras in the architectural and planning decisions of buildings of the late 19th – early 20th centuries have become the subject of comprehensive research.
Examining the Effects of Animal-Assisted Activities Against Standard Treatment in a University Setting
Authors: Islam Sanjidah , Spruin Elizabeth , Wornast Tracey , Dempster Tammy
Published: June 2023

The wellbeing of university students has become a global issue in recent years, with the rise of students seeking help for their mental health, the demand for such services has increased exponentially, leading many Universities to struggle in meeting these growing demands. With research in the area manly focused on formal methods of student support, the current study explores the use of more informal sources of support. 100 university students who had attended a standard informal student support session (known as Chooseday Chill) or a wellbeing dog session, were asked to complete a questionnaire measuring their anxiety and overall wellbeing. Results indicated that when compared to the standard support, students who attended the wellbeing dog sessions reported significantly lower levels of anxiety and higher levels of wellbeing at the end of the sessions. The authors discuss the practical implications of these findings for treatment in Higher Education.
Cat attacks towards people and/or animals, an educational pending task on pet’s owners?
Authors: González Pech Pedro , Medina-Barrera Valentina
Published: June 2023

This study aimed to explore the context and the characteristics of domestic cats’ (Felis catus) attacking their owners or other pets and their probable risk factors. A survey was targeted to persons perceiving that their cat attacked to people or/and animals. Only no-stray, healthy cats’ information were included. 48 questions covered general information of the owners, and type of house; age sex, color, and medical record of cats; the context on which the aggression to people or other pet took place; handling habitudes in owner-cat interaction. Chi-square and Fisher test were used to compare the frequency of cat’s characteristics between cats with and without attacks towards people and/or animals. Risk factors analysis was made with WinEpi©. The information of 154 cats was obtained, the 91.5% of owners declared to play with their cats, 63 cats performed attacks to people and/or animals in the past three months. 8 (5.2%) cats perceived by their owners as non-aggressive, in fact performed attacks towards people and/or animals. The most commons wounds reported were scratches and bites (68.2%), largely considered by owners (76.2%) as no needing medical revision. 62% of aggression events were preceded by vocalization and/or body posture changes of cats. A significant higher proportion of cats combining < 2years, and with nonexclusive litter box performed aggressions. Cats of age of < 2 years resulted with 4.7 to 32.2 more probabilities to perform aggression. The absence of other animals also resulted as risk factor. Owner attitudes minimizing cat aggression could imply the maintenance of unwanted behaviors in cats, also accidental aggression during human-animal interaction deserve deeper studies due to possible zoonosis risk to owners.
The southern Wyoming Laramide basin: implications for long-term tectonic control on uplift and subsidence
Authors: Minor Keith P. , Steel Ronald J. , Olariu Cornel , Wroblewski Anton F.-J.
Published: June 2023

An evolving tectonic setting during the Late Cretaceous and Paleocene drove the dramatic transformation of southern Wyoming from a broad marine shelf setting to a series of lacustrine basins. Early dominant control of depositional patterns by flexural tectonics gave way to control by dynamic topography and Laramide-style deformation. The southern Wyoming region demonstrates how progressive partitioning by Laramide movements exerted increasingly dominant control on regional depositional patterns. It did this by creating a long-lived, Laramide uplift-bounded fluvial catchment and basin largely controlled by Laramide-driven subsidence. The Rock Springs and Rawlins uplifts underpinned the basin and exerted their influence in the subsurface. Episodes of Laramide-driven subsidence produced a series of embayments, including the large Rusty–Allen Ridge embayment and the very large deepwater Lewis embayment. The degree of eustatic control in the region would have been greatest at short time scales in the low coastal–shallow-marine settings, causing shoreline oscillations. Several long transgressive episodes followed relatively punctuated progradational periods of coastal-plain construction when supply was generally high from the thrust belt and surrounding uplifts. Laramide activity in the Paleocene led to enclosure of the fluvial basin and the development of a series of smaller marine embayments that mark the end of influence in the region by open and coastal marine processes.
Projeto de extensão
Authors: Bottoli Schemmer Raffael , Cristina Hinckel Nágila , Aparecida Zotti Solange
Published: June 2023

Este documento descreve o projeto de extensão intitulado “Configuração, montagem, instalação e manutenção de computadores”, que foi proposto e executado entre os meses de agosto e dezembro de 2020, tendo sido realizado de forma remota e síncrona. Para a realização das aulas síncronas, foi utilizada a ferramenta Google Meetings e para realização das atividades do projeto de forma assíncrona, a ferramenta Google Classroom. Neste trabalho são descritas todas as atividades realizadas e desenvolvidas pelo projeto, em uma seção intitulada de diário reflexivo. Já todo o conhecimento aprendido pelos alunos e as percepções dos monitores do projeto, são descritas e documentadas em uma seção intitulada de percepção dos estudantes. Este projeto de extensão teve ao todo 350 candidatos inscritos e 100 alunos selecionados. Durante sua execução, concluíram o curso 42 alunos que atenderam aos critérios mínimos de presença e realizaram as atividades propostas pelo projeto. Ao todo, o projeto aconteceu em 15 encontros síncronos em que foram desenvolvidos 15 módulos, em 15 semanas. Por fim, este projeto contou com o apoio de 5 monitores, que facilitaram o processo de ensino/aprendizagem dos alunos do projeto. Sob a questão pedagógica do processo, é interessante observar as percepções dos monitores do projeto, não apenas acerca do amadurecimento dos assuntos/conhecimento dos conteúdos estudados, mas também das abordagens pedagógicas utilizadas pelos mesmos, no sentido de promover o aprendizado dos alunos. Também, é interessante observar no que trata o despertar do senso de importância dos assuntos aos monitores, o que cria vocação pelo exercício da profissão.
Fábrica de Tecnologias (FABTEC)
Authors: Leite Marcela , Curvello Rodrigo , Becker Adriele , Henrique Dechring Eifler Pedro , Alexandre Sebold Mateus
Published: June 2023

Para aprimorar o desempenho acadêmico e permitir a realização de projetos de pesquisa, ensino e extensão, foi criada a Fábrica de Tecnologias (FabTec). Trata-se de um laboratório para o desenvolvimento de ideias, projetos e parcerias, voltado ao desenvolvimento de software e hardware para solucionar demandas do meio acadêmico e da comunidade local. Essa proposta tem o objetivo de proporcionar vivências práticas dos conceitos vistos em sala de aula para aplicá-los em um problema do mundo real, possibilitando assim o desenvolvimento do senso crítico e profissional dos alunos participantes. O artigo apresenta alguns projetos em desenvolvimento na FabTec e seus resultados obtidos até o momento. Com a experiência adquirida na execução dos projetos, foi proposto um processo de desenvolvimento, metodologias e ferramentas necessárias para a gestão e acompanhamento da realização dos projetos. Além disso, tem-se como resultado o aperfeiçoamento do desempenho dos alunos envolvidos e seus depoimentos indicando a eficácia do projeto.
Construção de saberes na extensão universitária
Authors: Santana Silva dos Santos Denise , Cristo Santos Vitória Valéria , Lessa Cerqueira Medeiros Amanda , Souto Teixeira Bianca , Santos de Souza Ravena
Published: June 2023

Diante da pandemia da COVID-19, tornou-se necessário disseminar saberes capazes de prevenir e proteger a saúde da população. Nesse sentido, visando alcançar contextos vulneráveis como de crianças e adolescentes da Casa de Acolhimento do Complexo Penitenciário de Salvador (BA) e considerando as singularidades do público infantojuvenil, a História em Quadrinhos (HQ) foi a ferramenta lúdica selecionada para promover conhecimentos para essa faixa etária. Sendo assim, a aproximação do discente com a realidade vivenciada por este público proporciona subsídios teóricos para o processo de capacitação profissional, no sentido de minimizar os problemas de saúde apresentados. Portanto, este artigo tem como objetivo relatar a experiência de discentes do curso de enfermagem no desenvolvimento das atividades de extensão universitária na confecção de HQs para prevenção da COVID-19 entre crianças e adolescentes em contexto de vulnerabilidade social. Trata-se de um estudo descritivo, do tipo relato de experiência, referente às atividades desenvolvidas no projeto de extensão intitulado “Oficina remota para prevenção da COVID-19 com crianças e adolescentes na Casa de Acolhimento do Complexo Penitenciário”. A realização desta extensão universitária provocou a reflexão sobre um tema de importância internacional e as estratégias para abordá-lo de forma efetiva para o público infantojuvenil. As HQs construídas são um meio de mitigar vulnerabilidades e inequidades impostas às crianças em situação de abrigo institucional. Assim, a produção de HQs configura um avanço nas atividades de educação em saúde com crianças e adolescentes, uma vez que se trata de uma tecnologia que pode potencializar o processo ensino-aprendizagem.
Optimal Spectrum Granularity for Spectrally-efficient Elastic Optical Networks
Authors: UJJWAL UJJWAL
Published: June 2023

In this paper, we compute the optimal slot width which provides a good trade-off between the blocking probability and network cost to attain spectral and cost-efficient solution for the next generation optical networks. Here we have determined the blocking performance by varying the slot width from 50 GHz down to 1.5625 GHz followed by the estimation of the network cost by taking into account various network elements viz., transponder, node equipment’s (OXC, SSS, splitter/combiner) and optical amplifiers. Further, an evaluation of the trade-off between blocking performance and network cost is carried out to get the optimal slot width.
ADRC with Anti-Saturation for Uncertain HighADRC with Anti-Saturation for Uncertain High-Order Nonlinear MASs with Random Disturbances and Communication Delays
Authors: Wei Wenjun , He Zhizhen
Published: June 2023

This paper presents an Active Disturbance Rejection Consensus (ADRC) algorithm for high-order uncertain nonlinear multi-agent systems (MAS) with input saturation and time-varying communication delay in completely unknown perturbations. The proposed ADRC algorithm achieves dynamic consensus of MAS while simultaneously handling uncertain nonlinearity, external disturbance, communication delay, and input saturation of the system. The algorithm uses a linear extended state observer (LESO) to estimate the MAS's uncertain nonlinear terms and stochastic perturbations. Based on the estimated states, a distributed ADRC control law using a generalized saturation function is proposed to handle input saturation and communication delay, ensuring that all agents reach consensus. Furthermore, an upper bound on the delay of the MAS is given by using the generalized Lyapunov-Krasovskii function method, which provides the stability of the closed-loop system under a strongly connected and directed graph. Finally, numerical simulations are presented to demonstrate the effectiveness of the proposed strategy.
The “GU-GU-RU project” to eliminate discrimination related to the health effects of the Fukushima nuclear accident
Authors: Amir Isamu , Eguchi Yuichiro , Saotome Kosaku , Ogawa Soichiro , Kojima Yoshiyuki , Tamaki Tomoaki , Tsubokura Masaharu
Published: June 2023

Background: Although 12 years have passed since Great East Japan Earthquake and following Fukushima nuclear accident, approximately 40% of Japanese citizen still believe that the current radiation exposure in Fukushima residents will likely cause genetic effects of radiation. This misunderstanding could continue unexpected discrimination and prejudice towards those from Fukushima now and in the future. In order to provide updated knowledge and eliminate rumors related to radiation, Japanese Ministry of the Environment has launched “GU-GU-RU project” in 2021 with consisting of five sections.
Objective: To discuss the objectives and effects of the “GU-GU-RU Project” (results after the first year), to present administrative measures that may be effective in the long-term to prevent unjustified discrimination and prejudice, and to eliminate rumors in the event of future large-scale disasters, including radiation disasters.
Methods: We showed the contents of each sections carried out under the project and observed the result of first-year activities in each section.
Results: Among the programs, the “Radiation College” has steadily produced positive results, with nearly 1,300 students participating and 50 students sharing their thoughts and ideas. In addition, the project has adopted strategies such as creating and broadcasting a TV program and collaborations with manga, which are expected to have a significant impact on society.
Conclusions: Compared to previous efforts on disseminating information related to health effect of radiation exposure, the “GU-GU-RU Project” has taken a different approach in providing information of radiation and its health effects, which could become a better understanding of health effects of radiation for the general public.