bluuebunny/crossref_metadata_2025 huggingface dataset:
Foreign Accents in the Early Hiring Process: A Field Experiment on Accent-Related Ethnic Discrimination in Germany
Authors: Schmaus Miriam , Kristen Cornelia
Published: October 2021

Based on a field experiment conducted in Germany between October 2014 and October 2015, this article focuses on the disadvantages associated with the presence of a foreign accent in the early hiring process, when applicants call in response to a job advertisement to ask whether the position is still available. We examine whether a foreign accent influences employers’ behaviors via productivity considerations and/or whether foreign-accented speech is related to statistical discrimination or tastes among employers or customers that translate into differential treatment. To address these processes, we supplement our field-experimental data with information on job and firm characteristics from the texts of vacancy announcements and advertising companies’ homepages, on labor supply from the Federal Employment Agency, and on anti-immigrant attitudes from the German General Social Survey. Results suggest that while calling with a Turkish name did not result in a lower rate of positive replies, this rate was reduced for candidates who called with a Turkish accent. Turkish-accented applicants were told more often than the advertised position was already filled. Our findings suggest that the difference in response rates was not due to productivity considerations related to how well individuals understood foreign-accented speakers. Instead, results support the notion that the observed disadvantages were linked to discrimination based on employers’ ethnic tastes. While we found no indications pointing to the relevance of customer tastes or statistical discrimination, we cannot rule out these processes altogether. Our findings demonstrate that language cues can be more relevant than applicants’ names in shaping employers’ initial responses. They, thereby, highlight the need to consider multiple ethnic cues and different stages of the hiring process.
The Interplay of Jargon, Motivation, and Fatigue While Processing COVID-19 Crisis Communication Over Time
Authors: Shulman Hillary C. , Bullock Olivia M. , Riggs Elizabeth E.
Published: October 2021

Using the backdrop of the COVID-19 pandemic, this three-wave experiment ( N = 1,830) examined whether a public health crisis motivates people to engage with complicated information about the virus in the form of jargon. Results revealed that although the presence of jargon negatively impacted message acceptance for topics that were not particularly urgent (flood risk and federal risk policy), the presence of jargon within the COVID-19 topic condition did not affect message perceptions—at first. In subsequent waves of data collection, however, it was found that the influence of jargon strengthened over time within the COVID-19 topic condition. Specifically, jargon began to exert a stronger influence on processing fluency despite the continued urgency of the topic. This finding suggests that motivation to process COVID-19 related information declined over time. Theoretical contributions for language, processing fluency, and persuasion are offered and practical implications for health, risk, science, and crisis communicators are advanced.
Discussion: Making Sense of Public Sensemaking Relative to the COVID-19 Crisis
Authors: Bangerter Adrian
Published: October 2021

Disease outbreaks motivate human groups to engage in sensemaking efforts to give meaning to the event. These sensemaking processes often involve narratives framing where a disease comes from, how it spreads, and how to prevent and cure infections. At least four generic narratives are typically used as symbolic resources make sense of disease outbreaks: A medical science narrative and three lay narratives, i.e., (1) infectious disease as divine punishment, (2) infectious disease as caused by actions of outgroups (3) infectious disease as caused by evil elites. The contributions to this Special Issue are discussed in relation to this narrative sensemaking perspective.
Measuring levels of self-esteem of students with visual impairments in regular schools in Tanzania
Authors: Kapinga Orestes Silverius , Aloni Mbwiga
Published: October 2021

The global statistics show that more than 2.2 billion people are either faced with vision impairment or blindness. Visual impairment has been shown to affect young people’s emotional and psychological well-being, and has a profound effect on education attainment. This study assessed the levels of self-esteem of students with visual impairments in regular secondary schools in Tanzania. This was a cross-sectional research study. Self-esteem of students with visual impairment was studied in a group of 55 students included in two regular secondary schools enrolling students with visual impairments in Ruvuma and Iringa regions in Tanzania mainland. A set of self-esteem aspects was used to construct the outcome variable. Levels of self-esteem of students were obtained using the Rosenberg Self-Esteem Scale. The findings show 7.3% and 92.7% of students with visual impairments constitutes low and high self-esteem respectively. Levels of self-esteem for students with visual impairments were independent of students’ class ( p = .440), sex ( p = .528) and type of disability ( p = .169). Intrinsic self-esteem is more advocated among students with visual impairments in regular secondary schools in Tanzania. Further study on the relationship between levels of self-esteem and students’ performance needs to be addressed. Self-esteem was self-reported by students without any means of confirmation of the responses. This may have affected the estimated prevalence levels of students’ self-esteem.
CEDEL2: Design, compilation and web interface of an online corpus for L2 Spanish acquisition research
Authors: Lozano Cristóbal
Published: October 2021

This article presents and reviews a new methodological resource for research in second language acquisition (SLA), CEDEL2 ( Corpus Escrito del Español L2 ‘L2 Spanish Written Corpus’), and its free online search-engine interface ( cedel2.learnercorpora.com ). CEDEL2 is a multi-first-language corpus (Spanish, English, German, Dutch, Portuguese, Italian, French, Greek, Russian, Japanese, Chinese, and Arabic) of L2 Spanish learners at all proficiency levels. It additionally contains several native control subcorpora (English, Portuguese, Greek, Japanese, and Arabic). Its latest release (version 2) holds material from around 4,400 speakers, which amounts to over 1,100,000 words. CEDEL2 follows strict corpus-design criteria (Sinclair, 2005) and L2 corpus-design recommendations (Tracy-Ventura and Paquot, 2021), and all subcorpora are equally designed to be fully contrastable, as recommended by Contrastive Interlanguage Analysis (Granger, 2015). Thanks to its design and web interface, CEDEL2 allows for complex searches which can be further narrowed down according to its SLA-motivated variables, e.g. first language (L1), proficiency level, self-reported proficiency level, age of onset to the L2, length of exposure to the L2, length of residence in a Spanish-speaking country, knowledge of other foreign languages, type of task, etc. These CEDEL2 features allow L2 researchers to address SLA questions and hypotheses.
Model-Based ROC Curve: Examining the Effect of Case Mix and Model Calibration on the ROC Plot
Authors: Sadatsafavi Mohsen , Saha-Chaudhuri Paramita , Petkau John
Published: October 2021

Background

The performance of risk prediction models is often characterized in terms of discrimination and calibration. The receiver-operating characteristic (ROC) curve is widely used for evaluating model discrimination. However, when comparing ROC curves across different samples, the effect of case mix makes the interpretation of discrepancies difficult. Further, compared with model discrimination, evaluating model calibration has not received the same level of attention. Current methods for examining model calibration require specification of smoothing or grouping factors.

Methods

We introduce the “model-based” ROC curve (mROC) to assess model calibration and the effect of case mix during external validation. The mROC curve is the ROC curve that should be observed if the prediction model is calibrated in the external population. We show that calibration-in-the-large and the equivalence of mROC and ROC curves are together sufficient conditions for the model to be calibrated. Based on this, we propose a novel statistical test for calibration that, unlike current methods, does not require any subjective specification of smoothing or grouping factors.

Results

Through a stylized example, we demonstrate how mROC separates the effect of case mix and model miscalibration when externally validating a risk prediction model. We present the results of simulation studies that confirm the properties of the new calibration test. A case study on predicting the risk of acute exacerbations of chronic obstructive pulmonary disease puts the developments in a practical context. R code for the implementation of this method is provided.

Conclusion

mROC can easily be constructed and used to interpret the effect of case mix and calibration on the ROC plot. Given the popularity of ROC curves among applied investigators, this framework can further promote assessment of model calibration.

Highlights

Compared with examining model discrimination, examining model calibration has not received the same level of attention among investigators who develop or examine risk prediction models. This article introduces the model-based ROC (mROC) curve as the basis for graphical and statistical examination of model calibration on the ROC plot. This article introduces a formal statistical test based on mROC for examining model calibration that does not require arbitrary smoothing or grouping factors. Investigators who develop or validate risk prediction models can now also use the popular ROC plot for examining model calibration, as a critical but often neglected component in predictive analytics.
The history of magnetic resonance imaging and its reflections in Acta Radiologica
Authors: Smith Hans-Jørgen
Published: October 2021

The first reports in Acta Radiologica on magnetic resonance imaging (MRI) were published in 1984, four years after the first commercial MR scanners became available. For the first two years, all MR papers originated from the USA. Nordic contributions started in 1986, and until 2020, authors from 44 different countries have published MR papers in Acta Radiologica. Papers on MRI have constituted, on average, 30%–40% of all published original articles in Acta Radiologica, with a high of 49% in 2019. The MR papers published since 1984 document tremendous progress in several areas such as magnet and coil design, motion compensation techniques, faster image acquisitions, new image contrast, contrast-enhanced MRI, functional MRI, and image analysis. In this historical review, all of these aspects of MRI are discussed and related to Acta Radiologica papers.
Unproductive Workers and State Repression
Authors: Munro Kirstin
Published: October 2021

Social Reproduction Theory, as advanced by scholars such as Bhattacharya (2017) and Ferguson (2019), is at its core a theory of the revolutionary capacity of “unproductive” workers such as teachers, nurses, and social workers who are disproportionately women and disproportionately employed by the state. However, Social Reproduction Theory overlooks the contradictory and antagonistic role of the state in the lives of people, as the reproduction of labor power in capitalism proceeds via antagonism and state repression. The task of teachers, nurses, and social workers is the production of not just any life but that of a docile, exploitable worker.

JEL classification: B51, B54, P1, I3
Out of the Comfort Zone! Family Leaders’ Subsidiary Ownership Choices and the Role of Vulnerabilities
Authors: Pongelli Claudia , Calabrò Andrea , Quarato Fabio , Minichilli Alessandro , Corbetta Guido
Published: October 2021

Based on the socioemotional wealth approach and a sample of 3,904 subsidiary ownership choices made by 586 family firms, this study shows that family-managed firms (i.e., those family firms with a family member in a leadership position) prefer wholly owned subsidies over joint ventures when entering foreign markets. Family-managed firms are also more likely to revise their subsidiary ownership choices and form joint ventures when in vulnerability conditions, that is, when they experience performance below aspirations and when entering a culturally distant market.
Design Philanthropy: Challenges and Opportunities in the Evolution of Philanthropic Giving
Authors: Lyon Melissa Arnold , Bretas Shani S. , Ready Douglas D.
Published: October 2021

Over the past several decades large philanthropies have adopted aggressive approaches to education reform that scholars have labeled venture philanthropy. These efforts focused on broad changes to schooling and education policy, borrowing techniques from the venture capital world. But many foundations have recently become convinced that market forces and macro-level policymaking alone cannot drive educational improvement, particularly in areas related to classroom teaching and learning. In response, foundations have begun to design their own instructional innovations and identify providers to implement them. This paper interprets these recent efforts as early evidence of a distinct adaptation in the evolving role of philanthropies, which we dub design philanthropy. Although this approach represents an attempt by foundations to simultaneously increase democratic engagement, directly influence the instructional core, and spur educational innovation, it poses new risks for coherence, scalability, and sustainability in education policymaking.
Adaptation Trajectories of Dismissed Workers: A Critical Case Study of the Lithuanian Radio-Electronics Sector
Authors: Martinaitis Žilvinas , Sadauskaitė Audronė , Barzotto Mariachiara
Published: October 2021

This article explores why some dismissed workers adapt successfully to the changing structure of an economy, while others remain trapped in low-quality jobs and experience deskilling. The associated case study relies on in-depth, semi-structured interviews with 50 former employees of four bankrupt radio-electronics factories in Lithuania. It is found that workers with ‘inherited’ skills that are deep and technical are able to enter high-quality jobs when new firms emerge, recombining the physical, financial and human assets of destitute factories for new productive uses. However, if such economic opportunities are scarce, workers with inherited broad skill sets are relatively more successful in transitioning to services from manufacturing. Further, in line with the literature of the sociology of work, women and older workers are found to face more acute challenges in adapting to the economic shock associated with dismissal.
Footballers’ citizenship during COVID-19: A case study of Premier League players’ community support
Authors: Smith Dr Charlie V L
Published: October 2021

This paper demonstrates the community support of Premier League football players during the first COVID-19 national lockdown in the United Kingdom (March to May 2020). Given the global popularity and influence of footballers’ behaviour, it shows that they play an important role as citizens in supporting wider communities during circumstances such as the COVID-19 pandemic. A content analysis of 376 Premier League football players (80% of those registered) comprising 3877 posts on Instagram and Twitter is presented. The findings show 12 athlete citizenship roles during the pandemic which collectively illustrates players fostering support for fans and citizen's public health compliance, wellbeing and lives. Players also conveyed how they coped with the pandemic with their athlete mindset and were hopeful for a better future. The discussion and conclusion suggest that COVID-19 has presented an opportune time to renegotiate the complex social systems of which athletes are a part, identifying how they can engage in citizenship and future community support embracing the fullest range of their sporting profession.
Whole blood platelet impedance aggregometry with the ROTEM platelet device: comparison of 2 anticoagulants and storage times for the establishment of canine reference intervals
Authors: Heimgartner Lara M. , Stirn Martina , Kutter Annette P. N. , Sigrist Nadja E. , Jud Schefer Rahel
Published: October 2021

The ROTEM platelet device, a point-of-care whole blood platelet impedance aggregometer, is an add-on to the rotational thromboelastometry ROTEM delta device. The latter has been validated in dogs. We examined whether canine whole blood is suited for analysis with the ROTEM platelet device using adenosine-5′-diphosphate (ADP) and arachidonic acid (ARA) as agonists for platelet activation, and if there are significant differences between sample storage times and anticoagulants used. Subsequently, we determined canine reference intervals (RIs) for the ROTEM platelet device for ADP and ARA. In a pilot study, we examined whole blood from 7 dogs after 15-min and 60-min storage of lithium-heparinized samples and 40-min and 80-min storage of hirudinized samples. Statistical analysis showed no significant differences between ROTEM platelet device results for both ADP and ARA in lithium-heparin and hirudin anticoagulated canine whole blood. Lithium-heparinized blood samples analyzed after 15-min storage had the lowest coefficient of variation. RIs were determined for heparinized whole blood samples from 49 dogs after 15 min of storage.
Knowledge and Power Relations in Older Patients’ Communication About Medications Across Transitions of Care
Authors: Ozavci Guncag , Bucknall Tracey , Woodward-Kron Robyn , Hughes Carmel , Jorm Christine , Joseph Kathryn , Manias Elizabeth
Published: October 2021

Communicating about medications across transitions of care is a challenging process for older patients. In this article, we examined communication processes between older patients, family members, and health professionals about managing medications across transitions of care, focusing on older patients’ experiences. A focused ethnographic design was employed across two metropolitan hospitals. Data collection methods included interviews, observations, and focus groups. Following thematic analysis, data were analyzed using Fairclough’s Critical Discourse Analysis and Medication Communication Model. Older patients’ medication knowledge and family members’ advocacy challenged unequal power relations between clinicians and patients and families. Doctors’ use of authoritative discourse impeded older patients’ participation in the medication communication. Older patients perceived that nurses’ involvement in medication communication was limited due to their task-related routines. To reduce the unequal power relations, health professionals should be more proactive in sharing information about medications with older patients across transitions of care.
Primary Desmoplastic Small Round Cell Tumor of the Femur: Case Report and Review of a Rare Intraosseous Malignancy
Authors: Sharma Aarti E. , deVries John A. , Agrawal Caitlin , Haydon Rex C. , Krausz Thomas , Pytel Peter , Cipriani Nicole A.
Published: October 2021

Background: Desmoplastic small round cell tumors (DSRCT) are malignant neoplasms of young males arising most commonly in the abdominopelvic cavity, with a subset originating from extra-abdominal soft tissues. As either primary or metastatic lesions, they are rare in intraosseous sites. Case Presentation: We describe the fifth report of primary DSRCT of bone. A healthy 18-year old male presented with a blastic, 17 cm lesion within the left distal femur, suspicious for osteosarcoma or Ewing sarcoma. Subsequent biopsy revealed nests of small round blue cells infiltrating through a desmoplastic stroma. These cells were diffusely positive for epithelial markers, with paranuclear staining for desmin and focal reactivity with NSE. Break-apart FISH revealed a rearrangement in EWSR1, and RNA fusion panel confirmed WT1 as its partner in the pathognomonic t(11;22)(p13;q12) rearrangement. PET/CT showed widespread metastatic disease to visceral and bony sites. Conclusions: Due to their rarity as well as clinicopathologic and immunomorphologic overlap, primary intraosseous DSRCT can create diagnostic challenges with the more frequently encountered tumors of bone.
Clarifying Relations Between ADHD and Functional Impairment in Adulthood: Utilization of Network and Machine Learning Approaches
Authors: Goh Patrick K. , Martel Michelle M. , Jones Payton J. , Bansal Pevitr S. , Eng Ashley G. , Elkins Anjeli R. , Thaxton Melina H. , Barkley Russell A.
Published: October 2021

Using network analysis and random forest regression, this study identified attention-deficit/hyperactivity disorder (ADHD) symptoms most important for indicating impairment in various functional domains. Participants comprised a nationally representative sample of 1249 adults in the United States. Bridge symptoms were identified as those demonstrating unique relations with impairment domains that, in total, were stronger than those involving other symptoms. Results suggested three inattentive (i.e., difficulty organizing; does not follow through; makes careless mistakes) and one hyperactive ( difficulty engaging in leisure activities) bridge symptoms. Random forest regression results supported bridge symptoms as most important (compared to other symptoms) for predicting global and specific impairment domains. Hyperactive/impulsive symptoms appeared more strongly related to impairment in women, whereas difficulty organizing and easily distracted appeared more related to impairment in men. Clarification of bridge symptoms may help identify core characteristics of ADHD in adulthood and specify screening and intervention targets to reduce risk for related impairment.
Utility of the Limited Prosocial Emotions Specifier in Preschoolers With Conduct Problems
Authors: Bansal Pevitr S. , Goh Patrick K. , Eng Ashley G. , Elkins Anjeli R. , Thaxton Melina , Martel Michelle M.
Published: October 2021

This study examined the clinical utility of the “Limited Prosocial Emotions” (LPE) specifier (i.e., prevalence rates, group differences, and predictive utility) in a high-risk preschool sample ( N = 109, M age = 4.77) presenting with conduct problems (CPs; n = 59). First, LPE prevalence rates ranged from 7.7% to 89.8%. Next, few group differences were observed between with CP-only and CP+LPE; youth with CP+LPE differed from youth with CP-only on callous-unemotional (CU) traits and verbal ability, but not on externalizing or internalizing psychopathology, nor on parenting experiences. In the full sample, youth with LPE differed from youth without LPE on externalizing and internalizing psychopathology, parenting, and verbal ability. Finally, LPE predicted greater baseline CP but did not predict trajectories of CP. Findings highlight the clinical utility of the LPE specifier during early childhood and call for a refinement of the LPE specifier to improve its clinical value.
Catalyzing Navigation for Breast Cancer Survivorship (CaNBCS) in Safety-Net Settings: A Mixed Methods Study
Authors: Dixit Niharika , Sarkar Urmimala , Trejo Evelin , Couey Paul , Rivadeneira Natalie A. , Ciccarelli Barbara , Burke Nancy
Published: October 2021

Purpose

The current number of breast cancer survivors (BCS) in the United States is approximately 3.8 million, and this number is further expected to increase with improvement in treatments. Survivorship care plans (SCPs) are patient-centered tools that are designed to meet cancer survivors' informational needs about their treatment history, recommended health care, and health maintenance. However, the data on SCP benefits remain uncertain, especially in low-income and racial and ethnic minority cancer survivors. Patient navigation is an effective intervention to improve patient adherence and experience of interdisciplinary breast cancer treatment.

Objectives

This study sought to understand the role of lay patient navigators (LPN) in survivorship care planning for BCS in safety-net settings.

Methods

This study is a mixed methods pilot randomized clinical trial to understand the role of patient navigation in cancer survivorship care planning in a public hospital. We invited BCS who had completed active breast cancer treatment within 5 years. LPNs discussed survivorship care planning and survivorship care-related issues with BCS in the intervention arm over a 6-month intervention period and accompanied patients to their primary care appointment. LPNs also encouraged survivors to discuss health care issues with oncology and primary care providers. The primary objective was to assess BCS’ health-related quality of life (HRQOL). The secondary objectives were self-efficacy and implementation. We assessed implementation with 45–60-min semi-structured interviews with 15 BCS recruited from the intervention arm and 60-min focus groups with the oncologists and separately with LPNs.

Results

We enrolled 40 patients, 20 randomized to usual care and 20 randomized to LPN navigation. We did not find a statistically significant difference between the two arms in HRQOL. There was also no difference in self-efficacy between the two arms. Qualitative analysis identified implementation barriers to intervention that may have contributed to less effective intervention.

Implications for Cancer Survivors

Future survivorship care planning interventions need to consider: Cancer survivors’ needs and preferences, the need for dedicated resources, and the role of electronic health records in survivorship care plan delivery.
How to Achieve Standardization? Diluted Russell Viper Venom Test for Lupus Anticoagulant Detection in a Chinese Female Population
Authors: Lu Feng , Dai Qingkai , Wang Yuefang , Zhang Xia , Zhang Ge
Published: October 2021

On an international scale, guidelines and proposals for lupus anticoagulant detection have been published over the last 20 years, but until now, standardization has not been completely realized. The aim of this study was to evaluate the different ways of interpreting the results of lupus anticoagulant detection for standardization. A retrospective review of 15 447 instances of lupus anticoagulant detection by the diluted Russell Viper Venom test for female patients presenting with problems relating to the areas of reproduction, gynecology and obstetrics was performed. Lupus anticoagulant data were compared between different departments, months, reagent lots and cutoffs. Significant differences were found in patient data between different reagent lots, especially between lots of screening reagents (monthly average: highest 37.96 s vs lowest 33.88 s) and in the positive rates of lupus anticoagulant by different detection cutoffs (47.58% by using LA1/LA2 > 1.20 without normalization as a cutoff in Lot 1 vs 1.52% by using LA1 > 44 s as a cutoff in Lot 3). Compared with the cutoff using the value above the 99th percentile of LA1 for the healthy donors per lot, the cutoff using integrated tests with normalization had the smaller deviation of positive rate between different reagent lots. Pregnant women had higher LA1/LA2 levels than nonpregnant women. Based on the results, normalization is needed because there are significant lot-to-lot variations. Integrated tests with normalization might be a better standard by which to confirm lupus anticoagulant. Pregnant women should have population-specific cutoffs because they have higher LA1/LA2 levels.
Violence Against North Korean Refugee Women: Doubly Victimized By Repatriation and Premigration Traumatic Experiences
Authors: Kim Eunyoung , Yun Minwoo , von Denkowski Cordula
Published: October 2021

This study investigates the influence of traumatic events on the mental health of North Korean refugee women by examining the prevalence and severity of posttraumatic stress disorder (PTSD), depression, and anxiety in comparison with their male counterparts (women = 496; men = 131). Our results suggest that women are at greater risk of developing mental health problems than men. In particular, symptoms of PTSD and anxiety were higher among women who experienced forced repatriation to North Korea, which is operationalized as a constellation of gendered traumatic incidents such as sexual abuse, rape, witnessing infanticides, and forced abortion. The policy implications of our results and suggestions for future studies are discussed.
Towards Ethical International Research Partnerships in Gender-Based Violence Research: Insights From Research Partners in Kenya
Authors: Weber Sanne , Hardiman Margaret , Kanja Wangu , Thomas Siân , Robinson-Edwards Nicole , Bradbury-Jones Caroline
Published: October 2021

Research with survivors of gender-based violence in low- and middle-income countries is important to improve understanding of experiences of violence and the policies that can help combat it. But this research also implies risks for survivors, such as re-traumatization, safety concerns, and feelings of exploitation. These risks are magnified if research is undertaken by researchers from high-income countries, whose positionality produces power inequalities affecting both participants and research partners. This article describes the ethical challenges of international gender-based violence research from the perspective of Kenyan researchers and organizations and identifies recommendations about how to prevent them.
Violence Against Incarcerated Women: Predicting Risk Through the Lens of Childhood Harm
Authors: Wolff Nancy , Aizpurua Eva , Peng Dan
Published: October 2021

Victimization is common inside prisons and much remains unknown about the predictors of violence against incarcerated women. A sample of 564 incarcerated women was used to examine the link between in-prison victimization, childhood (physical, sexual, and emotional) harm, and mental illness. Nearly half or more of women reported childhood harm and over one-quarter experienced in-prison victimization. Childhood harm fell into four latent classes and low sexual abuse and high abuse classes predicted resident-on-resident sexual victimization, as did single types of childhood harm. Current depressive symptoms and perceptions of overcrowding predicted physical and sexual victimization perpetrated by residents and correctional staff.
Mass Murder in America: Trends, Characteristics, Explanations, and Policy Response
Authors: Fox James Alan , Levin Jack
Published: October 2021

Mass murder, especially involving a firearm, has been a subject of increasing interest among criminologists over the past decade. Lacking an existing and reliable data resource for studying these crimes, several organizations have launched their own database initiatives with, unfortunately, little consensus on definition. As a result, there is confusion regarding the nature and trends of such events. In this paper, we rely on the Associated Press/USA Today/Northeastern University Mass Killing Database, which provides the widest coverage of incidents in the U.S. with four or more victim fatalities, regardless of location, situation, or weapon. First, we present trends in incidents and victimization of mass killings from 2006 through 2020, followed by an examination of various incident, offender, and victim characteristics, distinguishing among the major subtypes. Next, we detail a motivational typology of mass murder and identify the common contributing factors. Finally, we consider the potential effects of certain policy responses related to media coverage, mental health services, and gun restrictions on the prevalence of mass killing.
Sutureless Tectonic Mini-Descemet's Stripping Automated Endothelial Keratoplasty (“mini-DSAEK”) for the management of corneal perforations
Authors: Roberts Harry W. , Gunasekera Chrishan D. , Law Elizabeth M. , Seifelnasr Mohamed , Giannaccare Giuseppe , Busin Massimo , Myerscough James
Published: October 2021

Purpose

To report the outcomes of a new technique, pull-through sutureless ‘mini-DSAEK’, to manage corneal perforations secondary to different aetiologies including trauma, neurotrophic ulcer following penetrating keratoplasty (PK), herpes simplex keratitis and microbial keratitis.

Methods

In this retrospective case series, we report the clinical outcomes of five cases of sutureless tectonic mini-DSAEK performed in patients presenting with large corneal perforations to Southend University Hospital between November 2019 and October 2020. One corneal perforation was sufficiently peripheral for the tectonic mini-DSAEK graft to be successfully positioned outside of the central visual axis. Four corneal perforations were central or paracentral for which the tectonic grafts involved the visual axis.

Results

Anterior chambers remained deep and formed with no evidence of leak in all subsequent follow ups in all patients representing 100% tectonic success. All tectonic grafts remained attached except one partially detached graft. One patient underwent uneventful phacoemulsification with intraocular lens implant 8 months after the primary intervention with excellent visual outcome. Two patients underwent two-piece mushroom PK and one patient underwent triple procedure (cataract extraction   +   intraocular lens   +   PK) for visual rehabilitation 2–6 months after the primary intervention with good visual outcome.

Conclusion

Sutureless tectonic pull-through mini-DSAEK is a useful technique in the management of corneal perforations, with a number of advantages compared with conventional techniques.
Analysis of Aneuploidy Spectrum From Whole-Genome Sequencing Provides Rapid Assessment of Clonal Variation Within Established Cancer Cell Lines
Authors: Khalil Ahmed Ibrahim Samir , Chattopadhyay Anupam , Sanyal Amartya
Published: October 2021

Background:

The revolution in next-generation sequencing (NGS) technology has allowed easy access and sharing of high-throughput sequencing datasets of cancer cell lines and their integrative analyses. However, long-term passaging and culture conditions introduce high levels of genomic and phenotypic diversity in established cell lines resulting in strain differences. Thus, clonal variation in cultured cell lines with respect to the reference standard is a major barrier in systems biology data analyses. Therefore, there is a pressing need for a fast and entry-level assessment of clonal variations within cell lines using their high-throughput sequencing data.

Results:

We developed a Python-based software, AStra, for de novo estimation of the genome-wide segmental aneuploidy to measure and visually interpret strain-level similarities or differences of cancer cell lines from whole-genome sequencing (WGS). We demonstrated that aneuploidy spectrum can capture the genetic variations in 27 strains of MCF7 breast cancer cell line collected from different laboratories. Performance evaluation of AStra using several cancer sequencing datasets revealed that cancer cell lines exhibit distinct aneuploidy spectra which reflect their previously-reported karyotypic observations. Similarly, AStra successfully identified large-scale DNA copy number variations (CNVs) artificially introduced in simulated WGS datasets.

Conclusions:

AStra provides an analytical and visualization platform for rapid and easy comparison between different strains or between cell lines based on their aneuploidy spectra solely using the raw BAM files representing mapped reads. We recommend AStra for rapid first-pass quality assessment of cancer cell lines before integrating scientific datasets that employ deep sequencing. AStra is an open-source software and is available at https://github.com/AISKhalil/AStra .
Utilization of Community-Level Fluoride-Filtered Water and its Associated Factors in Dugda Woreda of East Shewa Zone, Oromia Region, Ethiopia
Authors: Almebo Awash , Mangasha Hunachew Beyene , Ashuro Zemachu , Soboksa Negasa Eshete , Kanno Girum Gebremeskel , Negassa Belay , Mangasha Adane Erimias , Ayinalem Alem Eskeziya , Aregu Mekonnen Birhanie
Published: October 2021

Background:

Long-term consumption of water containing an excessive amount of fluoride causes dental and skeletal fluorosis. De-fluoridation options differ in terms of scale, efficacy, long-term viability, and user acceptance. Therefore, this study aimed to identify the challenges of using fluoride-filtered water and its associated factors among households.

Methods:

A cross-sectional study was conducted from April to May, 2018 among 405 randomly selected households in Dugda Woreda of Ethiopia Rift Valley East Shewa Zone, Oromia Region. A structured interviewer-administered questionnaire was used to collect the data. SPSS version 20 was used to enter and analyze the collected data. Logistic regression analysis was used to identify association between dependent and independent factors and explained by odds ratio with 95%CI.

Results:

A total of 228 (56.3%) households were found to utilize fluoride filtered water from community water supply schemes for drinking and cooking purposes. No family history of fluorosis (AOR = 44.4, 95%CI: 18.8, 104.74), monthly income of less than 1000 ETB (AOR = 0.03, 95%CI: 0.004, 0.23), good knowledge of community fluoride filter schemes (AOR = 5.93, 95%CI: 1.30, 26.9), and not afford to pay bill of ⩾0.50 ETB [AOR = 0.4, 95%CI: 0.20, 0.91] were factors significantly associated with utilization of community-level fluoride-filtered water.

Conclusion:

In this study, more than half of the households used fluoride filtered water. Family monthly income, affordability, presence of family members with the history of fluoride exposure, and knowledge about community fluoride filter schemes were factors significantly associated with utilization of community-level fluoride-filtered water.
The TV recap as paratext: Energizing, contextualizing, and modifying The Bachelor Australia
Authors: McAlister Jodi
Published: October 2021

The TV recap has become one of the most ubiquitous forms of criticism in contemporary media culture, proliferating across multiple media spheres and domains. At its simplest, it provides an opportunity for people to catch up with what they have missed. However, it is also a space for engaging with reactions to a program: an inherently affective and social experience. This article seeks to theorize the TV recap, its uses, and its pleasures. It considers the recap as a form of paratext, and seeks to unpack its relationship to textuality. Specifically, it considers the practice of reality TV recapping, which often positions both recapper and reader/viewer as consuming the text ironically. This article uses a corpus of recaps of the 2020 season of The Bachelor Australia – including recaps by the author – to answer three questions: how does the recap energize, contextualize, and modify textuality?
Patient satisfaction with telehealth consultations in medical oncology clinics: A cross-sectional study at a metropolitan centre during the COVID-19 pandemic
Authors: O Parsonson Andrew , Grimison Peter , Boyer Michael , Horvath Lisa , Mahon Kate , Beith Jane , Kao Steven , Hui Mun , Sutherland Sarah , Kumar Sanjeev , Heller Gillian , McNeil Catriona
Published: October 2021

Introduction

The coronavirus disease 2019 (COVID-19) pandemic has resulted in a widespread adoption of telehealth (phone and video consultations) in cancer care worldwide. The aim of this study was to determine patient satisfaction with telehealth consultations with their medical oncologist at a tertiary cancer centre in Sydney, Australia.

Methods

Patients who attended a routine telehealth appointment at the medical oncology outpatient clinic were recruited to complete a questionnaire containing 16 items, each on a 5-point Likert scale regarding satisfaction levels in various aspects of telehealth and their willingness to continue telehealth after the pandemic. Patients were also invited to provide suggestions for improvement.

Results

In total, 150 patients were invited to participate, and 103 valid questionnaires were returned. Median age was 63 years (range: 25–90), 49% of patients were male, 63% of patients had advanced cancer and 81% were on active treatment. In total, 95% of participants indicated that they were satisfied (score ≥4) with telehealth. 82% of participants preferred to continue telehealth consultations after the coronavirus disease 2019 pandemic, but ideally with a mix of telehealth and in-person consultations. Phone appointments (vs. video, p < 0.002), patients with advanced cancer (vs. early, p < 0.036) and pre-chemotherapy/immunotherapy/targeted therapy treatment reviews (vs. follow-up appointments, p < 0.001) were significantly associated with a willingness to continue telehealth.

Discussion

Patients were overwhelmingly satisfied with telehealth during the study period and were willing to continue telehealth for some appointments beyond the coronavirus disease 2019 pandemic. More research into the effectiveness, safety and implementation of telehealth to compliment traditional face-to-face services for patient-centred cancer care is required.
Sex differences in social communication behaviors in toddlers with suspected autism spectrum disorder as assessed by the ADOS-2 toddler module
Authors: Ronkin Emily , Tully Erin C , Branum-Martin Lee , Cohen Lindsey L , Hall Christine , Dilly Laura , Tone Erin B
Published: October 2021

The Autism Diagnostic Observation Schedule, 2nd-edition (ADOS-2) Toddler Module is the current gold-standard measure of autism spectrum disorder (ASD), a neurodevelopmental condition more frequently diagnosed in toddler boys than girls. Some evidence suggests that behaviors assessed by the Toddler Module may capture an ASD phenotype that is more common among boys than girls. Focus on these behaviors may contribute to sex differences in ASD diagnoses. Particularly, the ADOS-2 may equivalently weight social communication behaviors on which boys and girls are expected to look similar and behaviors that which girls may, due to early socialization, perform differently than boys. As a consequence, the Toddler Module may fail to identify ASD in girls who should qualify for the diagnosis. The current study examined the possibility that some ADOS-2 items may function differently for boys and girls by testing the degree to which eight items equivalently related to a social communication latent factor across sexes in toddlers with suspected ASD. Inconsistent with hypotheses, tests of differential item functioning revealed no evidence of sex differences, suggesting that the Toddler Module assesses these eight items similarly for boys and girls. Examination of factor loadings point to Creativity/Imagination as an area of interest for future research.

Lay abstract

When toddlers are suspected of autism spectrum disorder (ASD), the gold-standard assessment technique is with the Autism Diagnostic Observation Schedule, 2nd edition (ADOS-2) Toddler Module, a behavioral observation system. ASD is a neurodevelopmental condition more frequently diagnosed in toddler boys than in toddler girls. There is some evidence that the ADOS-2 assesses behaviors that are more characteristic of boys with ASD than girls. Thus, it is possible that focusing on these behaviors contributes at least in part to why more boys are diagnosed than girls. Specifically, girls may show more social skills than boys during the ADOS-2 assessment due to their socialization histories, which may lead to missed diagnoses of ASD in toddler girls. The current study examined eight social behaviors assessed by the ADOS-2 in a sample of toddlers with suspected ASD to see if they contributed differently to the total score of those items. Examination of those items suggested that those social communication behaviors work the same for boys and girls with suspected ASD, which was inconsistent with hypotheses. However, examination of particular items raises the possibility of examining creative/imaginative play as an area for future research.
Caregiver strain among North American parents of children from the Autism Treatment Network Registry Call-Back Study
Authors: Lindly Olivia J , Shui Amy M , Stotts Noa M , Kuhlthau Karen A
Published: October 2021

Elevated caregiver strain is common and linked to poor health in parents of children with autism. Yet, little research has examined caregiver strain longitudinally and in geographically diverse samples of parents whose children have autism. This study aimed to (1) examine change in caregiver strain and (2) determine correlates of improved caregiver strain in North American parents of children with autism. This was a secondary analysis of data from the Autism Treatment Network Registry Call-Back Study, conducted from 2015 to 2017 on a random sample of children with autism spectrum disorder at 12 clinical sites in the United States or Canada. Child assessments and parent-reported questionnaires were completed at two time points 1 year apart. Caregiver strain was assessed with the Caregiver Strain Questionnaire. In total, 368 children had caregiver strain data at both times. Mean caregiver strain in parents did not significantly change between Times 1 and 2 (mean difference = 0.05, t(360) = 0.1, p = 0.92). Improved caregiver strain between Times 1 and 2 was associated with improved child adaptive functioning and externalizing problem behaviors. Caregiver strain was persistent and multi-factorial. Parent training to manage challenging child behaviors and adaptively cope may benefit this vulnerable parent population.

Lay abstract

Caregiver strain is the adverse impact that parents of children with emotional and behavioral issues including autism often experience (e.g. negative consequences of caregiving such as financial strain and social isolation; negative feelings that are internal to the caregiver such as worry and guilt; and negative feelings directed toward the child such as anger or resentment). This study showed that on average caregiver strain did not significantly change in North American parents of children with autism during a 2-year period. Improved caregiver strain was linked to improved child functioning and behavior. Routine assessment of caregiver strain and referral to evidence-based programming and supports may help alleviate some of the burden that families of children with autism commonly experience.
Study of stick–slip suppression and robustness to parametric uncertainty in drill strings containing torsional vibration tool using sliding-mode control
Authors: Tian Jialin , Wang Jie , Zhou Siqi , Yang Yinglin , Dai Liming
Published: October 2021

Excessive stick–slip vibration of drill strings can cause inefficiency and unsafety of drilling operations. To suppress the stick–slip vibration that occurred during the downhole drilling process, a drill string torsional vibration system considering the torsional vibration tool has been proposed on the basis of the 4-degree of freedom lumped-parameter model. In the design of the model, the tool is approximated by a simple torsional pendulum that brings impact torque to the drill bit. Furthermore, two sliding mode controllers, U1 and U2, are used to suppress stick–slip vibrations while enabling the drill bit to track the desired angular velocity. Aiming at parameter uncertainty and system instability in the drilling operations, a parameter adaptation law is added to the sliding mode controller U2. Finally, the suppression effects of stick–slip and robustness of parametric uncertainty about the two proposed controllers are demonstrated and compared by simulation and field test results. This paper provides a reference for the suppression of stick–slip vibration and the further study of the complex dynamics of the drill string.