bluuebunny/crossref_metadata_2025 huggingface dataset:
Fernan Díaz, quem teve que esperar 800 anos para se casar, ou: Sobre desleituras históricas e revisões canônicas
Authors: Costa Horácio
Published: February 2021

There are many poems of homoerotic bias/themes amongst the archive of the “cantigas de escárnio e mal-dizer”, which in general show traces of satire and/or disgust. Some characters of medieval Portugal are fo-cussed in series of such cantigas, composed by many Gallician and Portuguese troubadours. Cantiga 1479, collected at the Cancioneiro da Biblioteca Nacional is by Aires Pérez Vuitoron and deals with some Fernan Días, who probably was a royal justice, who seems to have developed delusions of marrying someone of his own gender –to general scorn. It is studied in the fundamental edition of the “Cancioneiro Escarninho” (i.e., “Scornful Poetry Collection”) organized by Rodrigues Lapa (1965). The present essay adopts a critical eye on the necessity of reshaping and re-reading the unread in the literary canon of the Portuguese language. Such a critical stance considers that the construction of memory –including the literary one– coincides with the construction of citizenry.
Adoption of Electronic Health Records (EHRs) in China During the Past 10 Years: Consecutive Survey Data Analysis and Comparison of Sino-American Challenges and Experiences
Authors: Liang Jun , Li Ying , Zhang Zhongan , Shen Dongxia , Xu Jie , Zheng Xu , Wang Tong , Tang Buzhou , Lei Jianbo , Zhang Jiajie
Published: February 2021

Background

The adoption rate of electronic health records (EHRs) in hospitals has become a main index to measure digitalization in medicine in each country.

Objective

This study summarizes and shares the experiences with EHR adoption in China and in the United States.

Methods

Using the 2007-2018 annual hospital survey data from the Chinese Health Information Management Association (CHIMA) and the 2008-2017 United States American Hospital Association Information Technology Supplement survey data, we compared the trends in EHR adoption rates in China and the United States. We then used the Bass model to fit these data and to analyze the modes of diffusion of EHRs in these 2 countries. Finally, using the 2007, 2010, and 2014 CHIMA and Healthcare Information and Management Systems Services survey data, we analyzed the major challenges faced by hospitals in China and the United States in developing health information technology.

Results

From 2007 to 2018, the average adoption rates of the sampled hospitals in China increased from 18.6% to 85.3%, compared to the increase from 9.4% to 96% in US hospitals from 2008 to 2017. The annual average adoption rates in Chinese and US hospitals were 6.1% and 9.6%, respectively. However, the annual average number of hospitals adopting EHRs was 1500 in China and 534 in the US, indicating that the former might require more effort. Both countries faced similar major challenges for hospital digitalization.

Conclusions

The adoption rates of hospital EHRs in China and the United States have both increased significantly in the past 10 years. The number of hospitals that adopted EHRs in China exceeded 16,000, which was 3.3 times that of the 4814 nonfederal US hospitals. This faster adoption outcome may have been a benefit of top-level design and government-led policies, particularly the inclusion of EHR adoption as an important indicator for performance evaluation and the appointment of public hospitals.
The Impact of the COVID-19 Pandemic on the Uptake of Influenza Vaccine: UK-Wide Observational Study
Authors: Bachtiger Patrik , Adamson Alexander , Chow Ji-Jian , Sisodia Rupa , Quint Jennifer K , Peters Nicholas S
Published: February 2021

Background

In the face of the COVID-19 pandemic, the UK National Health Service (NHS) extended eligibility for influenza vaccination this season to approximately 32.4 million people (48.8% of the population). Knowing the intended uptake of the vaccine will inform supply and public health messaging to maximize vaccination.

Objective

The objective of this study was to measure the impact of the COVID-19 pandemic on the acceptance of influenza vaccination in the 2020-2021 season, specifically focusing on people who were previously eligible but routinely declined vaccination and newly eligible people.

Methods

Intention to receive the influenza vaccine in 2020-2021 was asked of all registrants of the largest electronic personal health record in the NHS by a web-based questionnaire on July 31, 2020. Of those who were either newly or previously eligible but had not previously received an influenza vaccination, multivariable logistic regression and network diagrams were used to examine their reasons to undergo or decline vaccination.

Results

Among 6641 respondents, 945 (14.2%) were previously eligible but were not vaccinated; of these, 536 (56.7%) intended to receive an influenza vaccination in 2020-2021, as did 466 (68.6%) of the newly eligible respondents. Intention to receive the influenza vaccine was associated with increased age, index of multiple deprivation quintile, and considering oneself to be at high risk from COVID-19. Among those who were eligible but not intending to be vaccinated in 2020-2021, 164/543 (30.2%) gave reasons based on misinformation. Of the previously unvaccinated health care workers, 47/96 (49%) stated they would decline vaccination in 2020-2021.

Conclusions

In this sample, COVID-19 has increased acceptance of influenza vaccination in previously eligible but unvaccinated people and has motivated substantial uptake in newly eligible people. This study is essential for informing resource planning and the need for effective messaging campaigns to address negative misconceptions, which is also necessary for COVID-19 vaccination programs.
A Machine Learning Sepsis Prediction Algorithm for Intended Intensive Care Unit Use (NAVOY Sepsis): Proof-of-Concept Study (Preprint)
Authors: Persson Inger , Östling Andreas , Arlbrandt Martin , Söderberg Joakim , Becedas David
Published: February 2021

BACKGROUND

Despite decades of research, sepsis remains a leading cause of mortality and morbidity in intensive care units worldwide. The key to effective management and patient outcome is early detection, for which no prospectively validated machine learning prediction algorithm is currently available for clinical use in Europe.

OBJECTIVE

We aimed to develop a high-performance machine learning sepsis prediction algorithm based on routinely collected intensive care unit data, designed to be implemented in European intensive care units.

METHODS

The machine learning algorithm was developed using convolutional neural networks, based on Massachusetts Institute of Technology Lab for Computational Physiology MIMIC-III clinical data from intensive care unit patients aged 18 years or older. The model uses 20 variables to produce hourly predictions of onset of sepsis, defined by international Sepsis-3 criteria. Predictive performance was externally validated using hold-out test data.

RESULTS

The algorithm—NAVOY Sepsis—uses 4 hours of input and can identify patients with high risk of developing sepsis, with high performance (area under the receiver operating characteristics curve 0.90; area under the precision-recall curve 0.62) for predictions up to 3 hours before sepsis onset.

CONCLUSIONS

The prediction performance of NAVOY Sepsis was superior to that of existing sepsis early warning scoring systems and comparable with those of other prediction algorithms designed to predict sepsis onset. The algorithm has excellent predictive properties and uses variables that are routinely collected in intensive care units.
Machine learning prediction of mild cognitive impairment conversion in a cohort of normal, non-demented elderlies (Preprint)
Authors: Drima Eduard , Vrabie Camelia
Published: February 2021

BACKGROUND

In aged subjects, mild cognitive conversion is difficult to assess from the clinical and medico-legal perspective as minimal changes are difficult to interpret.

OBJECTIVE

To evaluate how a machine learning algorithm (k-nearest neighbors) can predict conversion to mild cognitive impairment in a cohort of aged subjects with normal cognition, based on brain MRI data (hippocampus volume, whole brain volume), demographics and psychometric performance data.

METHODS

The study used raw imaging, demographics and psychometric tests result downloaded from OASIS (an open database dedicated to brain aging investigation). We used OASIS 1 and 2 datasets (T1-1.5T MRI). Within OASIS 2 (longitudinal) all subjects that converted (normal cognition - mild cognitive impairment) were carefully matched with normal controls and created a training set (28 cases). All normal patients form OASIS1 (81 cases) were included in a testing set. The right hippocampus was manually segmented and measured in all cases. MTA was measured as well. Psychometric test results and brain volume were available and were included as machine learning algorithm instances. After a training phase, normal patients from the test set were evaluated and classified by kNN algorithm. All machine learning files are provided in an annex.

RESULTS

Based on algorithm classification, 11 subjects from the OASIS 1 dataset (13.6%) were considered at risk for mild cognitive impairment conversion. The predicted time to conversion was calculated, using a linear regression algorithm, under two scenarios to 762.7±106.3 days (based on hippocampus volume) or 863.81±176.4 days (based on brain calculated volume) (p=0.11). Prediction was not confirmed in all cases but 6 subjects (7.5%) were identified between OASIS2 demented subjects based on demographic data (different identification labels).
Limitations: low images resolution made the manual hippocampus segmentation time consuming and subjective. The total absence of clinical data was seen as main limitation of this study.

CONCLUSIONS

After a supervised learning phase, a machine learning algorithm may predict very mild cognitive conversion based on anatomic, psychometric and demographic data analysis. Clinical data can improve prediction, making the machine learning process clinically useful.

CLINICALTRIAL

None
Source of Post-Transplant Care and Mortality among Kidney Transplant Recipients Dually Enrolled in VA and Medicare
Authors: Cashion Winn , Gellad Walid F. , Sileanu Florentina E. , Mor Maria K. , Fine Michael J. , Hale Jennifer , Hall Daniel E. , Rogal Shari , Switzer Galen , Ramkumar Mohan , Wang Virginia , Bronson Douglas A. , Wilson Mark , Gunnar William , Weisbord Steven D.
Published: February 2021

Background and objectives

Many kidney transplant recipients enrolled in the Veterans Health Administration are also enrolled in Medicare and eligible to receive both Veterans Health Administration and private sector care. Where these patients receive transplant care and its association with mortality are unknown.

Design, setting, participants, & measurements

We conducted a retrospective cohort study of veterans who underwent kidney transplantation between 2008 and 2016 and were dually enrolled in Veterans Health Administration and Medicare at the time of surgery. We categorized patients on the basis of the source of transplant-related care (i.e., outpatient transplant visits, immunosuppressive medication prescriptions, calcineurin inhibitor measurements) delivered during the first year after transplantation defined as Veterans Health Administration only, Medicare only (i.e., outside Veterans Health Administration using Medicare), or dual care (mixed use of Veterans Health Administration and Medicare). Using multivariable Cox regression, we examined the independent association of post-transplant care source with mortality at 5 years after kidney transplantation.

Results

Among 6206 dually enrolled veterans, 975 (16%) underwent transplantation at a Veterans Health Administration hospital and 5231 (84%) at a non–Veterans Health Administration hospital using Medicare. Post-transplant care was received by 752 patients (12%) through Veterans Health Administration only, 2092 (34%) through Medicare only, and 3362 (54%) through dual care. Compared with patients who were Veterans Health Administration only, 5-year mortality was significantly higher among patients who were Medicare only (adjusted hazard ratio, 2.2; 95% confidence interval, 1.5 to 3.1) and patients who were dual care (adjusted hazard ratio, 1.5; 95% confidence interval, 1.1 to 2.1).

Conclusions

Most dually enrolled veterans underwent transplantation at a non–Veterans Health Administration transplant center using Medicare, yet many relied on Veterans Health Administration for some or all of their post-transplant care. Veterans who received Veterans Health Administration–only post-transplant care had the lowest 5-year mortality.
STRATEŠKA KULTURA NEMAČKE U POSTHLADNORATOVSKOM PERIODU
Authors: Kesic Dusan
Published: February 2021

Revitalizovana moć Nemačke nakon ujedinjenja, prema prognozama neorealista, nužno je podrazumevala težnju da se data moć etablira preuzimanjem centralne uloge u Evropi. Kako se predviđanja neorealista o ,,balkanizaciji“ Evrope nisu se obistinila, to uslovljava da se analizi spoljne politike Nemačke pristupi iz perspektive koja će akulturalno i aistorijsko poimanje međunarodne politike neorealista oplemeniti kulturnom i istorijskom dimenzijom. Socijalno konstruktivistički pristup i koncept strateške kulture suprotstavljaju se aistorijskim i tzv. ,,objektivnim“ varijablama, u vidu materijalnih kapaciteta i tehnologije. Navedene varijable bivaju interpretirane kroz ,,sočiva“ strateške kulture, koja predstavlja kulturalno utemeljeno poimanje uloge rata u ljudskoj civilizaciji. Predmet ovog rada jeste sagledavanje uticaja koji je okončanje Hladnog rata imalo stratešku kulturu Nemačke. Cilj rada sastoji se u sagledavanju obrazaca ,,finih“ promena strateške kulture na nivou stanovišta bezbednosne politike. Navedeni cilj ostvaren je interpretacijom ključnog strateškog dokumenata Nemačke o bezbednosnoj politici. Analiza strateške kulture potvrdila je kontinuitet temeljnih vrednosti, što ujedno predstavlja i dominantno stanovište u akademskoj literaturi koja tematizuje ovo pitanje. Sa druge strane, identifikovan je diskontinuitet stanovišta bezbednosne politike, kao načina promocije temeljnih vrednosti kroz politiku. Izmene stanovišta bezbednosne politike bile su nužna posledica izmenjenih okolnosti na međunarodnoj sceni i potrebe za ,,pomirenjem“ temeljnih elemenata strateške kulture koji su stupili u koliziju. Definisanje uloge oružanih snaga javlja se kao centralni segment izmene strateške kulutre Nemačke u posthladnoratovskoj eri.
УГЛЕРОДНЫЕ КАРКАСНЫЕ НАНОМАТЕРИАЛЫ ДЛЯ НАНО-И БИОЭЛЕКТРОНИКИ
Authors: Куксин А.В. , Курилова У.Е. , Герасименко А.Ю.
Published: February 2021

Разработаны новые подходы создания углеродных каркасных наноматериалов для нано- и биоэлектроники с использованием лазерного излучения. Такие материалы могут использоваться для создания электропроводящих межсоединений в интегральных микросхемах и эмиссионных катодах, а также для электропроводящих имплантатов с улучшенными механическими и электрическими свойствами.
ТЕХНОЛОГИЧЕСКИЕ АСПЕКТЫ КОММУТАЦИИ КРИСТАЛЛОВ ПРИПОЙНЫМИ ШАРИКАМИ С ПОДКРИСТАЛЬНЫМ КОМПАУНДИРОВАНИЕМ
Authors: Змеев С.В.
Published: February 2021

Рассмотрены технологические аспекты процессов сборки кристаллов методом Flip-Chip с межкристальной бесфлюсовой коммутацией припойными шариками размером 60 мкм с подкристальной заливкой высокотекучими компаундами.
ВЛИЯНИЕ ВЕРХНЕЙ ГРАНИЦЫ РАЗДЕЛА НА ЭЛЕКТРИЧЕСКИЕ ХАРАКТЕРИСТИКИ ЯЧЕЕК РЕЗИСТИВНОЙ ПАМЯТИ НА ОСНОВЕ PT/SIOX/TIN
Authors: Мутаев И.А. , Дмитриева А.В. , Горнев Е.С. , Красников Г.Я. , Зенкевич А.В.
Published: February 2021

Исследовано влияние энергии конденсирующихся частиц при формировании верхнего электрода Pt на электрические характеристики ячеек резистивной памяти на основе Pt/SiOX/TiN. Показана связь между этим параметром и количеством генерируемых точечных дефектов на верхней границе раздела, которые критически влияют в дальнейшем на электрофизические характеристики мемристорных устройств.
SIMULATION OF A MULTI-FREQUENCY STOCKBRIDGE VIBRATION DAMPER OSCILATIONS WITH ENERGY SCATTERING HYSTERESIS
Authors: Danilin Alexander , Kurbatov Alexey , Zhavoronok Sergey
Published: February 2021

Spatial vibrations of a system containing a cable and a mass (solid body of arbitrary spatial configuration) are modeled. The problem is solved in a geometrically linear formulation, taking into account the hysteresis of energy scattering that is based on the kinematic equation. Identification of its parameters is carried out on the basis of experimental data on hysteresis loops of the limit cycle.
La reforma energética y el problema petrolero en México
Authors: Sovilla Bruno , Gómez-Ramírez Eusebio , Sánchez-Pérez Manuel
Published: February 2021

Desde la expropiación petrolera, y durante varias décadas, Petróleos Mexicanos (PEMEX) venía soportando el despegue del sector industrial. Así, a partir de los años 70 ha cumplido principalmente con dos funciones: generar divisa y contribuir en la financiación del gasto público a través del pago de impuestos. Hoy, sin embargo, la empresa petrolera enfrenta una crisis profunda. El objetivo de este trabajo es aclarar cómo se produjo la actual crisis energética por la que atraviesa el país, e indicar otros posibles caminos para afrontarla.  Utilizando datos oficiales del Instituto Nacional de Estadística y Geografía y de PEMEX se encuentra que en las últimas décadas las finanzas públicas han dependido, en gran medida, de los ingresos petroleros y, como consecuencia, PEMEX no ha podido llevar a cabo los proyectos de inversión necesarios para mantener o incrementar la producción. Como resultado, se ha exacerbado el declive de la producción, lo que ha creado las condiciones para la reforma energética a fin de atraer la inversión privada en este sector. Se concluye que una posible alternativa para evitar la privatización de un recurso natural tan estratégico como el petróleo sería aprobar una reforma fiscal que aumente los ingresos tributarios no petroleros, permitiéndole a PEMEX financiar la inversión necesaria para contrarrestar la caída de la producción.
La comunicación estratégica desde el mercadeo en instituciones educativas
Authors: Grajales-Montoya Nancy , Gómez-Bayona Ledy , Coronado-Ríos Bladimir
Published: February 2021

La gestión administrativa y académica de las organizaciones educativas ha evolucionado en la comprensión de aspectos comunicacionales que generen relacionamiento. Este estudio compara las tendencias entre las prácticas comunicacionales y las estrategias de mercadeo utilizadas en las Instituciones de Educación Superior (IES) del sector privado en Medellín-Antioquia. Para el análisis se hizo una revisión de literatura clasificada en dos fases: la primera, a partir de algunas bases de datos académicas; y la segunda, desde el análisis de las plataformas digitales de las instituciones en estudio. Los resultados arrojaron que se requieren habilidades comunicacionales que faciliten el acercamiento de las colectividades y rompan las barreras de la distancia, por lo que es importante desarrollar estrategias de mercadeo que estén vinculadas a la planeación organizacional para una acertada toma de decisiones. Se concluyó que las acciones de mercadeo desde la comunicación deben ser más estratégicas e intencionales en los diferenciales del portafolio de las instituciones y, al mismo tiempo, la oferta debe ajustarse a las necesidades del sector productivo y de la sociedad para ser competitivos.
Trends in Marketing Capabilities
Authors: Martin Silvia L.
Published: February 2021

Contemporary companies focus on marketing because of its importance and commercial advantages. Nevertheless, this also means they should face significant challenges and other organizations in this field. Firms require organizational structural factors to identify customer needs, consumer engagement, and market sensing. This is achieved through product exploration and exploitation, which increases the stock supply of SMEs for new and existing customers along with their profits. The adoption of electronic commerce has become essential for SMEs, especially in the IT sector, because it enables them to analyze several metrics, improve customer service, and reduce operating costs. In addition, they can be more efficient in distribution and customer communication. Thus, service promotes customer loyalty and improves confidence. New product development increases profits and creates opportunities to fulfill market needs. E-commerce opens new markets, supports customer service, and improves communication.  In summary, these three marketing capabilities are useful to gain competitive advantages in the long term and develop a differentiating factor against direct competition.
Paradigm shift in the management of metastatic Non-small Cell Lung Cancer
Authors: Gupta Ruby , Smalley Melanie , Anusim Nwabundo , Jindal Vishal , Rahi Mandeep Singh , Gupta Sorab , Gupta Sachin , Jaiyesimi Ishmael
Published: February 2021

Background: Lung cancer is one of the leading causes of cancer mortality
in the US. The use of precision medicine in the past 10 years has
significantly changed the therapeutic landscape of lung cancer.
Management of advanced non-small cell lung cancer (NSCLC) has
transitioned from a chemotherapeutic approach to targeted treatments and
immunotherapeutic agents. Several tyrosine kinase inhibitors (TKIs) have
been approved for patients with targeted mutations while patients who do
not have driver mutations; immunotherapy has been recently approved as
frontline therapy, which has resulted in marked improvement in overall
survival and added a new tool in our armamentarium. Aims: The purpose of
this review is to highlight recent advancements in diagnostic approach
and management strategies in patients with metastatic NSCLC. Materials
and methods: Published studies included in Medline (via PubMed) and
National Comprehensive Cancer Network Guidelines were reviewed for data
gathering. Conclusion: The use of next generation sequencing has
significantly changed our understanding of molecular oncogenic
mechanisms of lung cancer. These advancements have created a paradigm
shift in the treatment strategies of metastatic lung cancer from
primarily chemotherapeutic approach to increasing use of targeted
therapies and immune check point inhibitors (ICI) leading to better
survival rates and lesser toxicity.
CULTURE (YORÙBÁ) AS A MEANS OF DE-ESCALATING CONFLICT AND MAINTAINING PEACE
Authors: Olayinka Akintayo Sunday
Published: February 2021

Most works in peace and conflict studies concern interventions in
conflict situations – such as conflict management – or projects
seeking to sustain peace after a conflict, such as conflict resolution,
conflict transformation, and peace education. However, using a
peace lens, this study affirms culture as one of the means the Yorùbá
utilize to sustain peace in their community. The paper first ascertains
the presence of conflict and proceed to discuss how some features of
Yorùbá culture facilitate harmony as evidenced in the research findings.

Note: This article is based on a primary research among the Yorùbá of
southwest Nigeria within 2015 to 2020, the bulk of which is taken from
chapter 5 of the dissertation. A few amendments were made to suit the
requirement of this journal publication.
A look inside the black box of scientific publishing
Authors: Cavalleri Matteo
Published: February 2021

Publishing the results of one’s research is an integral part of the
scientific process, yet scholarly journals are often seen as black boxes
by researchers. What happens to a paper after it is submitted? Who is
deciding on its fate? What is the role of the journal editor and the
editorial office? How does the peer-review process work, and are its
core principles still relevant in today’s changing publishing landscape?

In this talk I will discuss these questions in an attempt to de-mystify
the peer review process from an editor’s perspective, and cover the
whats, the hows and the whys of peer review.
Avoiding COVID-19 Hospital Outbreaks: RT-PCR Swab and Clinical Assessment
Authors: Allievi Luca , Bongarzoni Amedeo , Tassinario Guido , Carugo Stefano
Published: February 2021

Nasopharyngeal RT-PCR swab test for COVID-19 diagnosis has a high
specificity but also a low sensitivity. The high false-negative rate and
the overconfidence in negative results sometimes lead to hospital
outbreaks. Therefore, we recommend always integrating the clinical
assessment in the diagnostic process, mostly after the test, to
determine what degree of confidence can be attributed to a negative
result.
Kushiyaki-related Streptococcus suis meningitis with ventriculitis: A case report
Authors: Kurihara Masaru , Nasu Michitaka , Itokazu David , Tokuda Yasuharu
Published: February 2021

This report describes Streptococcus suis meningitis with ventriculitis
in a 66-year-old kushiyaki chef, which presented with fever and
meningeal irritation signs. Cerebrospinal fluid testing revealed
increased cell counts and protein levels, and presence of gram-positive
cocci. Kushiyaki chefs are at high risk of this infection and
prophylaxis should be considered.
Financial security for the agrarian sector of Ukraine
Authors:   National University of Life and Environmental Sciences of Ukraine, Davydenko Nadiia , Bilyak Yuliia ,   National University of Life and Environmental Sciences of Ukraine, Nehoda Yuliia ,   National University of Life and Environmental Sciences of Ukraine, Shevchenko Nataliia
Published: February 2021

The agricultural sector of the economy is system-forming for Ukraine, guarantees the provision of food security of the state, forms the basis for the development of rural territories, influences environmental security, stimulates the development of other sectors of the economy. The level of financial security of the agrarian sector of the Ukrainian economy is caused by a number of factors, such as seasonal nature of production, limited shelf life of products, price disparity, low profitability, etc. Therefore, the purpose of the article is to analyze the development of the agro-industrial complex of Ukraine and the activities of the leading agroholdings of Ukraine, as well as to develop proposals for strengthening the financial security of the agricultural sector based on the results obtained. The goal of the study is based on a systematic approach and comparative economic analysis. The methodological basis is the general scientific methods and mechanisms for ensuring the financial security of enterprises. The conducted research has made it possible to establish that in recent years the financial security of the agricultural sector in Ukraine is carried out mainly through a set of programs, each of which is aimed at improving production efficiency. Over the past five years, capital investment and credit in agriculture have increased significantly. The article substantiates the need to manage the financial security of agro-industrial enterprises at the present stage of socio-economic development of Ukraine. The practical significance of the obtained results is determined by the fact that the conclusions and proposals can be used in the formation of the financial security strategy of the agricultural sector and the development of a mechanism for its implementation.
A discrete probability model suitable for both symmetric and asymmetric count data
Authors: Bhati Deepesh , Chakraborty Subrata , Lateef Snober
Published: February 2021

In this paper, an alternative discrete probability model, namely the
discrete skew logistic distribution, suitable for both asymmetric and
symmetric count data is proposed. Some important properties of the
distribution along with the estimation of the parameters are discussed. A
detailed Monte Carlo simulation study is carried out to assess the
performance of the maximum likelihood method and the method of proportion
for parameter estimation. Finally, the application of the proposed model is
discussed by considering two real-life datasets.
Fractional inequalities associated with a generalized Mittag-Leffer function and applications
Authors: Farid Ghulam , Mubeen Shahid , Set Erhan
Published: February 2021

Mittag-Leffer function is very useful in the theory of fractional differential
equations. Ostrowski?s inequality is very important in numerical
computations and error analysis of numerical quadrature rules. In this
paper, Ostrowski?s inequality via generalized Mittag-Leffer function is
established. In application point of view, bounds of fractional Hadamard?s
inequalities are straightforward consequences of these inequalities. The
presented results are also contained in particular several fractional
inequalities and have connection with some known and already published
results.
Inequalities for the generalized Tsallis relative operator entropy
Authors: Nikoufar Ismail , Yousefzadeh Zahra
Published: February 2021

In this paper, we present some inequalities for the generalized relative
operator entropy according to the generalized Tsallis relative operator
entropy. Our results are generalizations of some existing inequalities.
Fixed point theorems in WC-Banach algebras and their applications to infinite systems of integral equations
Authors: Banaś Józef , Krichen Bilel , Mefteh Bilel
Published: February 2021

The paper is devoted to prove a few fixed point theorems for operators acting
in WC-Banach algebras and satisfying some conditions expressed in terms of a
generalized Lipschitz continuity and measures of weak noncompactness.
Moreover, the assumptions imposed on the mentioned operators are formulated
with help of weak topology and weak sequential continuity. Our fixed point
results will be illustrated by proving the existence of solutions of an
infinite system of nonlinear integral equations.
Roasting temperature effect on the recovery of refractory gold and silver in pyrite concentrates
Authors: Zhang Y.-P. , Yang K. , Fang Y. , Robledo-Cabrera A. , Peng C.-S. , Lopez-Valdivieso A.
Published: February 2021

Pyrite concentrates with refractory gold and silver were roasted at different temperatures to improve the recovery of the metals by cyanide leaching. Scanning Electron Microscope characterization of the calcine revealed that the gold occluded in the pyrite less than one micron, and roasting produced channels in the concentrate, exposing the gold particles to the leaching solution. Gold and silver recoveries were maximum in the temperature range of 500-600?C due to the calcine high surface area and porosity. The Au and Ag recovery improved from 25 to 86% and 50 to 73%, respectively. The Au secondary encapsulation due to the sintering, the formation of the Ag-Fe-S species (Fe1?xS + Ag2S + Ag) and Ag ferrite in higher roasting temperatures hence Au and Ag recoveries decreased.
Active Funds and Bundled News
Authors: Lee Charles M. C. , Zhu Christina
Published: February 2021

We use trade-level data to examine the role of actively managed funds (AMFs) in earnings news dissemination. We find that AMFs are drawn to, and participate disproportionately more in, earnings announcements (EAs) that include bundled managerial guidance. When the two pieces of news are directionally inconsistent, AMFs trade in the direction of future guidance rather than current earnings. AMFs exhibit an ability to discern, and adapt their trading to, the bias in bundled guidance. While AMF trades at EAs are generally more profitable than their non-EA trades, this result reverses when guidance bias is extreme. Overall, we find that increased AMF trading during EAs leads to faster price adjustment. Collectively, these findings suggest that AMFs are sophisticated processors of bundled earnings news, and their trading generally improves market price discovery.

JEL Classifications: G12; G14; G23; M41.
Glucokinase Inactivation Paradoxically Ameliorates Glucose Intolerance by Increasing Beta-Cell Mass in db/db Mice
Authors: Omori Kazuno , Nakamura Akinobu , Miyoshi Hideaki , Yamauchi Yuki , Kawata Shinichiro , Takahashi Kiyohiko , Kitao Naoyuki , Nomoto Hiroshi , Kameda Hiraku , Cho Kyu Yong , Terauchi Yasuo , Atsumi Tatsuya
Published: February 2021

Efficacy of glucokinase activation on glycemic control
is limited to a short-term period. One reason might be related with the excess
glucose signalling by glucokinase activation towards beta-cells. In this study,
we investigated the effect of glucokinase haploinsufficiency on glucose
tolerance as well as beta-cell function and mass using a mouse model of type 2
diabetes. Our results showed that db/db
mice with glucokinase haploinsufficiency presented amelioration of glucose
tolerance by augmented insulin secretion associated with the increase in beta-cell mass when compared with db/db mice. Gene expression
profiling, and immunohistochemical and metabolomic analyses revealed that glucokinase
haploinsufficiency in the islets of db/db
mice was associated with lower expression of stress-related genes, higher
expression of transcription
factors involved in the maintenance and maturation of beta-cell function, less
mitochondrial damage, and a superior metabolic pattern. These effects of glucokinase
haploinsufficiency could preserve beta-cell mass under diabetic
conditions. These findings verified our hypothesis that
optimizing excess glucose signalling in beta-cells by inhibiting glucokinase
could prevent beta-cell insufficiency, leading to improving glucose tolerance
in diabetes status by preserving beta-cell mass. Therefore, glucokinase
inactivation in beta-cells could, paradoxically, be a potential strategy for
the treatment of type 2 diabetes.
Optimization of the ablation process using ultrashort pulsed laser radiation in different burst modes
Authors: Metzner D. , Lickschat P. , Weißmantel S.
Published: February 2021

The authors report on a solid-state burst mode amplified laser source capable of varying the pulse duration in the range of 0.24–10 ps and generating pulse trains (bursts) with an intraburst pulse repetition rate of 65 MHz (MHz burst mode) and 2.5 GHz (GHz burst mode). Furthermore, every pulse of a burst in the MHz burst mode can be divided into another GHz burst, called BiBurst. In this study, a laser radiating at 1030 nm wavelength is used to generate ablation areas and investigate the efficiency, the surface quality, and the process stability on stainless steel with different total fluences per burst, numbers of pulses per burst, and pulse durations in the MHz, GHz, and BiBurst modes. In the investigated parameter range, the highest efficiencies were obtained in the MHz burst mode with femtosecond pulses, but in this burst regime, the burst mode induced smoothing effect is dependent of the number of scans. In contrast, the process stability and the quality in the GHz and BiBurst are granted over a wide range of parameters. Thus, the actual advantages of the GHz and BiBurst regimes in terms of a high process stability and quality could be established.
Elementos mercadológicos necesarios para la subsistencia de la microempresa comercial, municipio de Chiautempan, Tlaxcala
Authors: Alonso Lozada Raúl , Villanueva Meléndez Armando , Montiel García Adriana , Espinoza Águila Ma. Luisa , Tizapantzi Sánchez Julissa
Published: February 2021

El objetivo de esta investigación fue analizar la incidencia de fracaso de microempresas comerciales del municipio de Chiautempan, Tlax (México), para lo cual se escogieron una serie de variables relacionadas con aspectos mercadológicos, así como otras de índole no financieras, aunque igualmente determinantes, como la educación, la experiencia previa, el género y la edad de los microempresarios. Asimismo, se formularon las siguientes tres hipótesis de trabajo: 1) la edad del propietario y su conocimiento en temas de mercadotecnia influyen de manera importante en el cierre de la microempresa comercial, 2) el género de quien emprende en una microempresa influye de manera importante en su falta de consolidación y 3) la educación y la experiencia previa en temas mercadológicos inciden en la consolidación de las microempresas comerciales. En el estudio participaron 27 microempresarios, a los cuales se les aplicó una encuesta, diseñada con la colaboración de profesores universitarios del área de mercadotecnia. Los resultados, por una parte, demuestran que el origen de ese fracaso de las microempresas se encuentra no solo en aspectos relacionados con el pago de la renta, la falta de clientes o mercado, sino también con la falta de estrategias mercadológicas, como la promoción en redes sociales, la identidad gráfica o conocer el producto ofrecido. En cuanto a las hipótesis planteadas, se puede decir que la edad y la educación del microempresario influyen en la consolidación del negocio. Asimismo, todavía prevalece la tendencia (masculina) en cuanto al género para los microempresarios. Afortunadamente, los índices reflejados en este estudio permiten afirmar que la brecha es cada vez más corta, por lo que progresivamente se irá minimizando la diferencia de oportunidades.
IMPACTS OF PATTERNS OF ECONOMIC AGENTS ACTIVITIES IN THE SEMERU VOLCANO CONSERVATION AREA
Authors: Segara Nuansa Bayu , Basyari Iin Wariin
Published: February 2021

Semeru volcano is the most popular mount hiking tourism in Indonesia. The economic community and conservation area are affected by these activities. This research focuses on the development activities of economic agents pattern and explains the impact of high tourism in the Semeru Volcano conservation area. It was a qualitative study, and the participative observatory was a procedure for collecting the data. The location was not limited in the Semeru Volcano, but also social media, Instagram. The result of the research reveals that there are two kinds of economic agents, namely internal and external. They have positive connectedness to support hiking activities. Although there should be potential for competition between open trip services and local guides, this does not happens, due to the wisdom of internal economic actors, especially local guides. Moreover, the consequences of high tourism activities in the Semeru Volcano conservation area are waste and erosion. The article is concluded by proposing several directions for economic agents to be involved more in conservation activities and positive business in the Semeru Volcano.Key words: Semeru Volcano, economic agent, conservation area, mount tourismGunungapi Semeru merupakan wisata pendakian gunung yang paling populer di Indonesia. Aktivitas ini tentu berdampak terhadap perekonomian penduduk sekitar dan lingkungan di kawasan konservasi. Artikel ini mengkaji pola aktivitas dan pelaku ekonomi yang terlibat dalam perkembangan wisata, dan mengungkap dampak tingginya aktivitas ini terhadap Kawasan Konservasi Gunungapi Semeru itu sendiri. Penelitian ini menggunakan pendekatan kualitatif yang bersifat ekploratif. Pengumpulan data dilakukan secara observasi partisipatif dan tidak terbatas di kawasan pendakian, namun juga melakukan observasi di media sosial instagram. Hasil penelitian menujukan pelaku ekonomi terdiri dari internal dan eksternal kawasan, yang memiliki keterkaitan positif antar pelaku ekonomi dari luar dan dalam Kawasan Pendakian. Meskipun semestinya ada potensi persaingan antara jasa open trip dengan pemandu lokal, akan tetapi hal itu tidak terjadi, karena kearifan pelaku ekonomi internal, khususnya para pemandu lokal. Dampak tingginya aktivitas wisata pendakian ini mengakibatkan dua permasalahan yang cukup serius, yaitu sampah dan erosi. Artikel ini diakhiri dengan memberikan beberapa usulan terkait dengan peningkatan keterlibatan pelaku ekonomi dalam melakukan usaha dan aktivitas konservasi di Kawasan Gunung Semeru. Kata kunci: Gunungapi Semeru, pelaku ekonomi, kawasan konservasi, wisata gunung
SILENT SIMULATION: THE ABILITY OF GEOGRAPHY EDUCATION STUDENTS TO DO A HORIZONTAL EVACUATION TO A TSUNAMI SAFE ZONE IN PADANG CITY
Authors: Nofrion Nofrion , Wijayanto Bayu , Rahmanelli Rahmanelli , Novio Rery , Surtani Surtani , Khairani Khairani , Zohir Ahmad Mohammad
Published: February 2021

This article was written to explain the ability of Geography Education students to do horizontal evacuation to a tsunami safe zone in Padang City and a silent simulation as an alternative of horizontal evacuation. In this research, respondents were asked to do horizontal evacuation in 3 ways, that is walking, power walking and running. The measurement result data were analyzed and compared with the estimated arrival time of tsunami wave in three scenarios based on gender. The results of the research are 1) 47.76 % of respondents did not know the nearest tsunami safe zone from their places; 2) if the earthquake and tsunami scenarios 1 and 2 occurred, the recommended horizontal evacuation technique was running. Silent simulation is a horizontal evacuation simulation carried out independently by residents without waiting for the simulation schedule by the government or related institutions. Silent simulation can be done alone, with family, or with the closest neighbours and combined with daily activities such as marathons or jogging. Through this silent simulation practice, residents can find out the most appropriate evacuation method and the fastest evacuation route to the nearest tsunami safe zone from their respective homes.Keywords: silent simulation, geography education, tsunami safe zone, PadangArtikel ini ditulis untuk menjelaskan kemampuan mahasiswa Pendidikan Geografi dalam melakukan evakuasi horizontal ke zona aman tsunami di Kota Padang dan silent simulation sebagai alternatif evakuasi horizontal. Dalam penelitian ini, responden diminta melakukan evakuasi horizontal dengan 3 cara, yaitu jalan kaki, jalan cepat dan lari. Data hasil pengukuran dianalisis dan dibandingkan dengan perkiraan waktu tiba gelombang tsunami pada tiga skenario berdasarkan jenis kelamin. Hasil penelitian adalah 1) 47,76% responden tidak mengetahui zona aman tsunami terdekat dari tempatnya; 2) jika terjadi gempa bumi dan tsunami skenario 1 dan 2, maka teknik evakuasi horizontal yang direkomendasikan adalah berjalan. silent simulation merupakan simulasi evakuasi horizontal yang dilakukan secara mandiri oleh warga tanpa menunggu jadwal simulasi oleh pemerintah atau instansi terkait. silent simulation bisa dilakukan sendiri, bersama keluarga, atau dengan tetangga terdekat dan dipadukan dengan aktivitas sehari-hari seperti maraton atau jogging. Melalui latihan silent simulation ini, warga dapat mengetahui metode evakuasi yang paling tepat dan jalur evakuasi tercepat menuju zona aman tsunami terdekat dari rumah masing-masing.Kata Kunci: Silent simulation, Pendidikan geografi, Zona aman tsunami, Padang
Pengaruh Pemahaman, Kesadaran, Tarif Pajak dan Pelayanan Perpajakan Usaha Mikro, Kecil dan Menengah di Kabupaten Karawang
Authors: Fauzi Ajeng Resti , Maula Kholida Atiyatul
Published: February 2021

The purpose of this research is to know the influence of understanding, awareness, tax rates and taxation services of SMES taxpayer compliance. One of the efforts to help the economic development is in the presence of SMES in Indonesia. Development and development of the country will grow more if the state financing runs smoothly. One of the Government's efforts for the state financing to run smoothly is that the government needs a sufficient source of country for the development of the country that is being done by paying taxes. The population in this study is a SME which includes SMES champion in Karawang Regency period 2019, amounting to 58 MSMES. Data is collected by spreading the questionnaire to SMES The study used multiple linear analysis techniques. In partial testing the results showed that tax awareness and tariffs were influential for taxpayer compliance, while understanding and taxation services had no effect on the taxpayer's obligation. In the simultaneous testing of research results shows that understanding, awareness, tax rates and taxation services jointly affect taxpayer compliance.
Hallazgo de dos brazaletes de la Edad del Bronce en 1832, durante las obras del Canal de Castilla a su paso por Cigales (Valladolid)
Authors: Delibes de Castro Germán , Escudero Navarro Zoa , Montero Ruiz Ignacio
Published: February 2021

Se informa del hallazgo en 1832 de un enterramiento con dos brazaletes del Bronce Final en Cigales (Valladolid). Realizado durante las obras del Canal de Castilla, se vincula al yacimiento de Sopeña, de los inicios de la Cultura del Soto o Soto Formativo. Además de la tipología de los objetos, se estudian su composición y la procedencia del metal en que fueron fundidos. Por último, el hallazgo se presta a debatir sobre el ritual funerario del tránsito Edad del Bronce-Edad del Hierro en el valle medio del Duero
Tengslin við heimilin trosnuðu merkilega lítið í fyrstu bylgju COVID-19: Sjónarhorn stjórnenda og grunnskólakennara
Authors: Jónsdóttir Kristín
Published: February 2021

Viðvera nemenda var minnkuð í langflestum grunnskólum vorið 2020 þegar fyrsta bylgja COVID-19 gekk yfir en á móti kom að upplýsingagjöf til foreldra var aukin og fjarkennsla tekin upp. Skipulag viðveru og fjarkennslu var mismunandi milli skóla og sveitarfélaga en allir væntu þess að nemendur lærðu heimavið.Þessi rannsókn beinist að viðhorfum skólastjórnenda og kennara. Þeir svöruðu spurningakönnun í apríl 2020 en svör bárust frá 151 grunnskóla af 170 skólum á landinu öllu. Niðurstöður sýndu að stjórnendum og kennurum var ljóst að aðstæður nemenda til náms heimavið væru mismunandi. Þeir lögðu mikla vinnu í að halda uppi kennslu og búa nemendur út með námsefni og verkefni. Kennarar vörðu meiri tíma en í venjulegu árferði í undirbúning kennslu og kennsluna sjálfa, sem og í upplýsingamiðlun og samskipti við heimilin. Stjórnendur og kennarar voru ánægðir með hvernig kennslan var á heildina litið en þeim fannst nokkuð skorta á að þátttaka foreldra í námi barna sinna væri eins góð og kennslan á þessum tíma. Bæði kennarar og stjórnendur lýstu áhyggjum af slakri mætingu nemenda af erlendum uppruna og þeirra sem hafa veikt bakland. Tengsl skóla og heimila styrktust frekar en veiktust á þessu tímabili þrátt fyrir álag í samfélaginu. Ályktun höfundar byggir á að (1) starfsfólk skóla lagði sig fram um að halda skólunum opnum og stýra góðri og vel undirbúinni kennslu af fagmennsku um leið og það fékk skýrari mynd af aðstæðum nemenda heimavið; (2) svo virðist sem foreldrar hafi fengið meiri innsýn í fjölbreytt og krefjandi viðfangsefni grunnskólanáms og oftast sýnt skólafólkinu þakklæti og virðingu; (3) samskipti heimila og skóla jukust verulega í flestum tilvikum og kennarar og foreldrar unnu saman eftir nýjum leiðum. Tengsl kennara við nemendur úr viðkvæmum hópum rofnuðu frekar en við skólasystkin þeirra svo neikvæð áhrif fyrstu bylgju faraldursins virðast hafa bitnað harðast á þeim