bluuebunny/crossref_metadata_2025 huggingface dataset:
Philosophy: Environmental risk policy and public law
Authors: Gillroy John Martin
Published: January 2025

Philosophy: Environmental risk policy and public law

John Martin Gillroy is Professor of Philosophy, Law & Public Policy at Lehigh University. Here, he navigates philosophy with a special focus on environmental risk within the realms of policy and public law. Human beings constantly look for assurances against uncertainty. Scientific data provides assurance, but it only examines the surface ‘facts’ of the causal world. Religion provides assurance, but it requires a belief in and allegiance to a particular definition of God. Philosophy is a hedge against uncertainty that is more essential than science. It does not require a single theological belief and gives one access to a range of systematic, logical arguments for applying practical reason to choices in an uncertain world.
Cell biology research: The mystery of cholesterol homeostasis
Authors: Ueda Kazumitsu
Published: January 2025

Cell biology research: The mystery of cholesterol homeostasis

Kazumitsu Ueda, PhD from Kyoto University, WPI-iCeMS, unveils the mystery of cholesterol homeostasis in this cell biology research focus. Cholesterol is a crucial component of the plasma membrane (PM) that surrounds every human cell, helping to maintain a distinct intracellular environment from the external one. While some cholesterol in the body is obtained from daily food, it is synthesised in all body cells, and cellular cholesterol concentration is highly regulated. However, cholesterol has gained a bad reputation for harming health. In this article, the physiological role of cholesterol will be reconsidered.
PERANCANGAN UI/UX SISTEM ABSENSI UMKM INDOMOM FOOD BERBASIS WEB MENGGUNAKAN GIS DENGAN METODE UCD
Authors: Yasmin Aysia Fatmi , Nugraha Bagja , Ridwan Taufik
Published: January 2025

In the continuously evolving digital era, the application of information technology has become key to operational efficiency, including in the management of human resources in the micro, small, and medium enterprises sector (SMEs). As a rapidly growing SME, Indomom Food struggles with the manual attendance management system's inefficiency and accuracy. To address this issue, this research aims to design a UI/UX prototype of a GIS-based web attendance system using the User Centered Design (UCD) method, which includes usage context, user and organizational needs, design solutions, and design evaluation. We expect the attendance system to use GIS to verify employee attendance based on location. The research results show that the designed system successfully meets user needs, with a System Usability Scale (SUS) score of 75 in the "Acceptable Good" category and a User Experience Questionnaire (UEQ) score in the "Above Average" to "Excellent" category. We expect this UI/UX design to assist in addressing the accuracy and efficiency issues in attendance management at Indomom Food SMEs.
Practical scaling-up of a four reactants multicomponent reaction (4-MCR)
Authors: Mondelo Rodríguez Abel , González León Denia , Verdecia Reyes Yamila , Forte Mesa Rionaldo , Nuñez Figueredo Yanier , Ochoa Rodríguez Estael
Published: January 2025

Context: Translation of any chemical process from laboratory to pilot or commercial scale is by no means a simple linear process. This process is influenced by several parameters, such as temperature, agitation speed, the concentration of reactants, and their interactions. In addition, temperature and agitation speed are very related to heat and movement transfers, which are two critical unit operations that affect the scale-up process and reaction yield. A multicomponent reaction (MCR) is a process where more than three reagents react through two or more reactions, producing one biggest molecule. Its scale-up is complex considering the complex nature of the reaction pathway. Our project involves a 4-MCR for obtaining a 3,4-pyridone derivative, a very important product for obtaining a neuroprotective compound. Despite its importance in medicinal chemistry, no report about the scale-up of MCRs was found.
Aims: To develop a practical way to scale up a multicomponent reaction with four components, from laboratory to pilot scales.
Methods: A combination of the brute force method and dimensionless numbers was applied for the scale-up process based on the significant physical forces governing the process.
Results: Experimentally, it was previously demonstrated that temperature and fluid agitation and their interaction are the most significant parameters affecting reaction yield. Its related unit operations, heat and movement transport, were selected as the critical physical forces for the scaling-up process. The dimensionless numbers related to those unit operations are the Nusselt and Reynold numbers. In addition to other criteria applied, those dimensionless numbers were used to calculate the agitation speed for the upper scale. Likewise, as the reaction product precipitated through the cooling process, the obstruction of the reactor discharge valve was observed. Thus, a critical agitation speed was determined at the laboratory scale by applying the Zwietering rule through direct observation of solid sedimentation in the reactor.
Conclusions: The process showed high reproducibility at all scales, reaching good yields of around 73%. Product purity was higher than 99% for all batches. The method applied allows the successful scalability of the process to increase the scale to commercial.
Molecular Insights: Gene Expression in HCC and Testicular Cancer among ALD Patients.
Authors: Fatima Hooriya , Maqbool Humayoun Huma , Ahmad Husna , Sheikh Nadeem
Published: January 2025

Background: Alcohol-associated liver disease (ALD) leads to anomalies of hepatocellular carcinoma (HCC), and steatohepatitis. Though tremendous efforts have been made during the past 2 decades, ALD pathogenesis remains obscure. Currently, computational data analysis related to the residues of ALD patients is not widely emphasized, so most attention is needed on differentially expressed genes associated with HCC.
Methodology: A comparison between GSM4194985 (Healthy) and GSM4194987 (ALD) was conducted through the GEO database with the accession ID GSE141100 in the form of Raw RNA counts.  IDEP analyzed data through bicluster heatmaps for upregulated and downregulated genes for potential effects of ALD on the patients followed by pathway analysis through Reactome.
Results: The study revealed the downregulated expression of KCNK15 alongside the upregulation of MLXIPL and ART4 owing to ALD discerning their progression in HCC. As KCNK15 and MLXIPL both are involved in metabolism, their pathway analysis alleged the dysregulation of ion and insulin homeostasis respectively could lead to the progression of HCC.  ADH1B downregulation raises the possibility of poor alcohol metabolism, which exacerbates liver damage. Dysregulation of MLXIPL, KCNK15, and ART4 may accelerate the development of HCC. Furthermore, this study suggests that impaired spermatogenesis in ALD patients is associated with overexpression of C5orf58, KCNE1, and AKAP3.
Conclusion: This study reveals the inclination of developing HCC in ALD patients based on the differential expression of KCNK15, MLXIPL, and ART4 genes and liver toxicity by ADH1B. The upregulation of C5orf58, KCNE1, and AKAP3 may lead to the defective spermatogenesis that may contribute to the development of testicular cancer owing to the upregulation of C5orf58, KCNE1, and AKAP3 in spermatogenesis.
THE CURRENT ISSUES OF TAX LEGISLATION IN KAZAKHSTAN IN THE CONTEXT OF GLOBALIZATION
Authors:   Yessenov University, MOLDAGALIYEVA A.
Published: January 2025

The article is devoted to the study of topical issues of the tax legislation of Kazakhstan in the context of globalization, with an emphasis on its transformation in recent years. The study analyzes changes in the country's tax policy caused by external and internal challenges, as well as the impact of international standards and global economic processes on the development of the national tax system. Special attention is paid to the issues of Kazakhstan's integration into international tax structures and the adaptation of legislation to the standards put forward by the Organization for Economic Cooperation and Development (OECD) and other international organizations. The author conducts a comparative analysis of the current tax legislation of Kazakhstan and its changes in the context of globalization, highlighting the key areas of reform. One of the main problems identified in the study is the need to strengthen the fight against transnational tax evasion, which is becoming especially relevant against the background of the digitalization of the economy and the growth of cross-border financial flows. The consequences of the introduction of digital technologies in tax administration, including the creation of automated reporting systems, which helps to improve tax collection and increase tax transparency, are considered. The study revealed contradictions in the current tax policy of Kazakhstan, in particular, in the field of taxation of multinational companies and tax disputes, as well as insufficient mechanisms for effective monitoring and control of international financial flows. The author suggests ways to solve these problems, including improving legislation, improving international cooperation and strengthening tax discipline. Based on the analysis, recommendations are proposed for further improvement of the tax system of Kazakhstan, aimed at increasing its flexibility, compliance with international standards and ensuring economic stability in the context of globalization.
THE CURRENT STATE OF PIPELINE CORROSION PROTECTION WITH POLYMER COATINGS
Authors:   Yessenov University, Aktau, Kazakhstan, Bekbauliyeva Aliya
Published: January 2025

Corrosion of pipelines is one of the main reasons for reducing their service life and operational characteristics. Pipelines are aggressively exposed to various external factors, such as chemical compounds, temperature fluctuations, mechanical loads, etc., which contributes to the development of corrosion. One of the most effective methods of corrosion protection is the use of polymer coatings, which form a reliable barrier between the metal surface and the aggressive external environment. The article discusses modern achievements in the field of polymer coatings for pipeline protection, their features, advantages and disadvantages, as well as application methods and applications. A wide range of polymer materials such as epoxy, polyurethane and polyethylene coatings are analyzed, as well as the prospects for their further improvement using nanotechnology.
THE USE OF INNOVATIVE TECHNOLOGIES IN SHIPBUILDING
Authors:   Yessenov University, Аktau, Kazakhstan, Patrov Fеdor
Published: January 2025

The article examines the current trends in the improvement of the shipbuilding industry in the context of the study of innovative technologies. The study includes the nuances of using 3D printing technologies in the construction of ships, the use of a ballast-free hull structure and high-elasticity carbon nanotube paper (buckypaper), in order to reduce harmful emissions into the atmosphere and increase the environmental friendliness of ships. Particular interest is paid to the use of these composite materials, which significantly increase efficiency and reduce the time of construction and automation of processes that contribute to increasing the safety and productivity of navigation by minimizing human errors and optimizing the operational data of ships.
Glider Surveillance for Near-Real-Time Detection and Spatial Management of North Atlantic Right Whales
Authors:   University of New Brunswick, Indeck Katherine , Baumgartner Mark , Lecavalier Laurence , Whoriskey Frederick , Durette-Morin Delphine , Pettigrew Neal , McSweeney Jacqueline , Thorne Lesley , Gallagher Katherine , Edwards Catherine , Meyer-Gutbrod Erin , Davies Kimberley
Published: January 2025

Successful area-based ocean management relies on long-term, persistent biological monitoring using reliable ocean observation assets. Underwater electric gliders fill a unique monitoring niche compared to other platforms because they can autonomously survey across diverse environments—from shallow coastal waters to remote offshore areas—for weeks to months at a time. Gliders equipped with passive acoustic monitoring (PAM) devices are capable of robust, continuous near-real-time monitoring of numerous species of whales. Here, we highlight five case studies to discuss how gliders are being used for area-based monitoring of the internationally migratory and critically endangered North Atlantic right whale to address several different spatial management objectives. Examples include dynamic management of shipping zones and fishery-area closures in Canadian waters, glider-based monitoring in the United States to mitigate vessel strikes and fishing gear entanglements, surveys to assess whale habitat use near offshore wind energy development areas in the northeastern United States, and surveillance of the coastal calving grounds in the southeastern United States. These examples illustrate how PAM-equipped gliders are being used to monitor an endangered cetacean species with complex conservation management needs across its range. These assets are supporting risk reduction measures across diverse regions, and their use is likely to continue to expand in support of species conservation and threat mitigation.
Development and characterization of voriconazole-oxalic acid dihydrate cocrystals for enhanced pharmaceutical performance
Authors: Nijhawan Monika , Jidige Bhavana , Aleti Rajeswari , Gunnam Sailaja , Saxena Trapti
Published: January 2025

Pharmaceutical cocrystallization is a promising alternative for improving the solubility and dissolution rate or manipulating other physical properties of active pharmaceutical ingredients. The objective of this investigation was to study the effect of cocrystallization to improve physicochemical properties of voriconazole (VZ). Liquid assisted grinding method was attempted for preparation of cocrystals. Melting point, Fourier transformation infrared spectroscopy (FTIR), powder X-ray diffraction (PXRD), and differential scanning calorimetry (DSC) techniques were employed to investigate the hydrogen bonding interaction, crystallinity and thermal behaviour of prepared cocrystals respectively. The pharmaceutical cocrystals were successfully obtained with oxalic acid dihydrate (OAD) in 2:1 stoichiometric ratio. The physicochemical properties of VZ and corresponding cocrystals were assessed in terms of saturation solubility and dissolution performance. The VZ cocrystals showed enhanced solubility and dissolution rate as compared with VZ. The VZ cocrystals (4.179 mg/mL) showed higher solubility in 0.1 N hydrochloric acid than VZ (3.140 mg/mL). Cocrystals showed higher dissolution rate than VZ. The enhancement in dissolution rate of VZ cocrystal from OA was 2.28-fold within 10 min.
Ethno-medicinal study of plants used for treatment of buffalo ailments by traditional healers in Marwar region, Rajasthan, India
Authors: Dudi Aishwarya , Singh Dheeraj
Published: January 2025

The objective of this current investigation was to explore the ethnoveterinary practices concerning plant use and formulation techniques in an undisclosed area of India. Additionally, the study aimed to identify potential medicinal plants with notable consensus factor and fidelity values for subsequent in vitro analysis. A total of 60 individuals were interviewed using a semi-structured questionnaire to gather information. Within the study area, 63 medicinal plants from 40 different families were documented for treating ailments in buffaloes. Notably, the Amaranthaceae family was most frequently cited for buffalo treatment. Analysis of growth forms revealed a dominance of woody plants, with shrubs comprising 30.16% and trees 28.57%, followed by herbs at 31.16% and climbers at 09.52%. A majority of the plants were found to be wild (63.49%) and perennial (73.01%). Leaves and roots were the preferred plant parts for remedies, followed by whole plants and seeds. The informant consensus factor (ICF) ranged from 0.83 for ophthalmic and poison effects to 0.97 for respiratory ailments, indicating a strong consensus among traditional healers regarding plant usage for various ailments. Vernoia cinerea exhibited the highest Fidelity Level (FL) value (81.25%), followed by Tecomella undulate (72.72%) and Curcuma longa (71.11%). Plants with high ICF and FL values warrant further investigation through phytochemical and pharmacological studies to validate their efficacy scientifically.
Estudio de la electrodeposición de Ni proveniente de baños reales
Authors: Castañeda Barrera Gilberto , Cabrera-Sierra Roman , Luna-Sánchez Rosa María
Published: January 2025

Las baterías secundarias de Ni-Cd gastadas son desechadas sin tratamientos previos en rellenos de basura, lo cual implica la contaminación de suelos por los metales Ni, Co y Cd que éstas contienen. La recuperación de níquel es económicamente atractiva a la industria por las aplicaciones que representa, mientras que el Co y Cd son carcinógenos. La extracción de estos metales puede llevarse a cabo a través de diferentes métodos. En el presente trabajo se realizó una metodología híbrida para la extracción de Ni, Co y Cd de baños reales. Los polvos recuperados de los polos positivos fueron lixiviados en medio de ácidos sulfúrico 1 M; posteriormente, la solución filtrada fue puesta en contacto con Cyanex 272 al 20%, con el fin de extraer Cd y Co de la solución. La solución acuosa rica en níquel fue electrodepositada sobre acero inoxidable para determinar los mejores parámetros de densidad de corriente, voltaje y pH.
Pengaruh Medan Magnet Elektromagnetik ELF 750 µT Terhadap Ketahanan Tempe
Authors: Sasikirana Berlian Nur , Putri Diana Ragilia , Astanafa Delania Sylva , Putri Elsa Ananda , Zakkiyah Halwa Fathimah , Nur I Meylan Aisyatun , Elizah Nur , Yushardi Yushardi , Arimukti Dyah Arum
Published: January 2025

Tujuan dari penelitian ini adalah untuk mengetahui bagaimana pengaruh medan magnet elektromagnetik ELF terhadap ketahanan tempe. Medan  elektromagnetik  (ELF)  adalah  sejenis  radiasi  non-pengion  karena  spektrum gelombang  elektromagnetiknya  memiliki  frekuensi  di  bawah  300  Hz.  Salah satu manfaat dari gelombang  ELF  yaitu  dapat  dimanfaatkan  untuk  mengawetkan  bahan  pangan.  Bahan pangan yang sering dijumpai, kerap memiliki daya tahan atau masa simpan yang terbatas, gelombang ELF ini dapat dimanfaatkan untuk menambah daya tahan atau masa simpan bahan makanan seperti tempe. Beberapa  Hasil penelitian menunjukkan bahwa paparan medan magnet ELF dapat meningkatkan pertumbuhan bakteri tertentu, yang berperan penting dalam proses  fermentasi makanan  seperti  tempe. Pada penelitian kali ini kita menggunakan metode eksperimen laboratorium  yang merupakan metode penelitian dengan tujuan menjelaskan hubungan antara sebab dan akibat dari satu variabel dengan variabel yang lain. Hasil dari penelitian menunjukkan bahwa dengan pemberian paparan medan magnet ELF, kualitas fermentasi meningkat, memperpanjang masa simpan, dan menjaga stabilitas kualitas tempe, sehingga teknologi ini memiliki potensi besar untuk diterapkan secara luas dalam industri pangan.
Percursos teórico-críticos e diferentes modos de leitura das literaturas africanas de língua portuguesa
Authors: Leite Ana Mafalda , Moreira Terezinha Taborda
Published: January 2025

Editorial.
A poesia que media e resiste:
Authors: Kubernat Carlos Oliveira , Pontes Newton de Castro , Martins Edson Soares
Published: January 2025

O presente estudo busca, por meio da análise de três poemas da obra Sangue Negro, de Noémia de Sousa, investigar as relações de sentindo que se estabelecem na poesia que configuram ao poeta a capacidade de traduzir uma realidade distante a dos leitores. Para isso, recorremos ao pesquisador Nazir Ahmed Can que conceitua esse procedimento como “mediação criativa”. Além dele, as teorias de Friedrich Schiller e Theodor Adorno sobre a criação poética são fundamentais para compreendermos como Noémia de Sousa consegue, esteticamente, representar uma voz coletiva; uma individualidade que toca uma percepção universal em Moçambique; e, por fim, uma articulação entre o lírico e a sociedade através da linguagem.
Revista Msaho (1952) , dança, canto e poesia:
Authors: Leal Luciana Brandão
Published: January 2025

Virgílio de Lemos idealizou a primeira publicação da Revista Msaho (1952), que contou com contribuições de textos assinados por ele, ortônimo, por seus heterônimos, além de outros poetas e intelectuais moçambicanos. Msaho propõe um “ritmo novo” para a lírica moçambicana, reivindicando os valores culturais africanos, em consonância com os movimentos da negritude e do pan-africanismo. Este artigo apresenta diversos registros do poeta Virgílio de Lemos e de seus heterônimos para o projeto da Revista Msaho (1952). A análise aqui proposta extrapola o primeiro número publicado e apresenta ideias que motivaram a concepção desse importante projeto literário. Muitos textos (poéticos e editoriais) não foram apresentados no primeiro e único número da Revista, sendo editados, posteriormente, na Antologia Jogos de Prazer (2009). Esses registros contribuem para o real e amplo entendimento da importância desse empreendimento para as letras moçambicanas.
Noemia, Paulina e as poéticas nos tempos
Authors: Vergueiro Filho Carlos Eduardo Pinto
Published: January 2025

Este artigo visa construir uma relação entre duas escritoras moçambicanas a partir dos textos presentes em Sangue Negro (2018), de Noemia de Sousa, e Niketche : Uma história de poligamia (2022), de Paulina Chiziane. Algumas categorias de análise foram elencadas para realizar a comparação: oralidades nos textos a partir das culturas endógenas; vozes poéticas, bem como a posição da narradora na ficção; experiência e contaminações do real no texto ficcional. O objetivo do artigo é dissertar sobre as permanências e mudanças na literatura moçambicana de autoria feminina em tempos históricos que vão do colonial ao pós-independência. O que aproxima as duas escritoras que viveram épocas diferentes? É possível uma aproximação da linguagem (ritmo, figuras, imagens, pontuações e outras) e das tópicas (lugar do feminino, liberdade, opressão, mundo do trabalho e outras) levantadas em seus respectivos textos? Como eles dialogam com os momentos históricos vividos pelas autoras e a formação da literatura moçambicana ao longo desse período? O texto será iniciado com um conjunto de questões para buscar possibilidades de contato visando a aproximação deles, bem como a integração com leitores de língua portuguesa. Por fim, nas considerações finais serão colocadas algumas hipóteses conclusivas, assim como alternativas investigativas posteriores que podem ser desdobradas.
Raízes e Ressonâncias a estética literária de Alice Goretti Pina na Literatura Contemporânea de São Tomé e Príncipe
Authors: Alves Roberta Maria Ferreira
Published: January 2025

Alice Goretti de Pina é uma escritora de São Tomé e Príncipe, cuja obra se caracteriza pela profunda conexão com as raízes culturais e tradições de seu país. Nascida como a oitava filha de Alice e Protásio, Goretti Pina desenvolveu desde cedo um interesse pela literatura, que se consolidou ao longo dos anos e a levou a se tornar uma voz importante da cena literária são-tomense. Sua produção literária é variada, abrangendo desde narrativas ficcionais, poesia e literatura infantil. Em suas obras, é comum encontrar uma abordagem intimista e poética da condição humana, frequentemente permeada por temas como a identidade, a cultura e a preservação das tradições de São Tomé e Príncipe. Goretti Pina é reconhecida por sua habilidade em equilibrar a preservação da herança cultural são-tomense com uma abordagem inovadora e contemporânea, que busca dialogar com um mundo cada vez mais globalizado sem perder de vista suas origens.
Filsafat dan Pembelajaran Bahasa Inggris: Keterkaitan dalam Konteks Kurikulum Merdeka Belajar
Authors: Munibi Ahmad Zaki , Zuriyati Zuriyati , Setiadi Samsi
Published: January 2025

Sebagai dasar dari berbagai disiplin ilmu, filsafat diintegrasikan ke dalam pembelajaran bahasa Inggris dalam konteks Kurikulum Merdeka Belajar. Penelitian ini bertujuan untuk menguraikan keterkaitan antara filsafat dan pembelajaran bahasa Inggris sesuai dengan prinsip-prinsip Kurikulum Merdeka Belajar. Metode yang digunakan dalam penelitian ini adalah kualitatif dengan pendekatan tinjauan literatur sistematis. Hasil penelitian menunjukkan adanya hubungan signifikan antara filsafat dan pembelajaran bahasa Inggris dalam kerangka Kurikulum Merdeka Belajar. Pertama, filsafat memberikan panduan bagi proses pembelajaran bahasa Inggris. Kedua, pembelajaran bahasa Inggris dapat dipandang sebagai aspek dari ontologi dalam filsafat. Ketiga, dalam konteks Kurikulum Merdeka Belajar, pembelajaran bahasa Inggris mengadopsi teori konstruktivisme. Keempat, pendekatan pembelajaran bahasa Inggris sejalan dengan pemikiran filsafat modern dan postmodern. Kelima, prinsip-prinsip filsafat moral diterapkan dalam pembelajaran bahasa Inggris untuk membangun kompetensi karakter Pancasila. Keenam, terdapat interaksi timbal balik antara filsafat dan pengajaran bahasa Inggris. Ketujuh, nilai-nilai aksiologis, epistemologis, dan ontologis filsafat tercermin dalam penilaian pembelajaran bahasa Inggris. Kedelapan, teori kebenaran dalam filsafat relevan dengan pembelajaran bahasa Inggris.
Kata kunci: Filsafat, Pembelajaran Bahasa Inggris, Kurikulum Merdeka
Testimonios de Transformación
Authors: Casillas Alcalá María Teresa
Published: January 2025

Este volumen especial  rinde un homenaje a la visión y al gran esfuerzo del Dr. Julián Gascón Mercado, un hombre íntegro y sensible a las necesidades de los nayaritas. Estaba seguro que la educación es una herramienta poderosa para transformar la vida de las personas y que la creación de una universidad en el Estado de Nayarit, significaba que los jóvenes no tendrían qué abandonar a su estado natal para buscar una educación superior de calidad.
ANALYSIS OF THE LABORATORY'S INTERNAL CONTROL
Authors: Дягилева Дарья Андреевна
Published: January 2025

В данной работе осуществляется изучение аспектов, связанных с организацией внутреннего контроля в лабораториях, включая ключевые функции и принципы эффективности таких процедур. Рассматриваются фундаментальные понятия управления качеством внутреннего контроля лаборатории, подчеркивается важность обоснованного внедрения проверок

This paper examines aspects related to the organization of internal control in laboratories, including key functions and principles of effectiveness of such procedures. The fundamental concepts of quality management of the laboratory's internal control are considered, and the importance of sound implementation of inspections is emphasized
TECHNOLOGY FOR PROCESSING A MIXTURE OF PHOSPHORUS AND SULFUR IN THE PRESENCE OF SULFUR AND CARBAMIDE
Authors: Aslanov A.Q.
Published: January 2025

The work shows the technology of obtaining nitrogen-phosphorus-sulfur complex fertilizers by activating phosphorites with a carbamide solution in the presence of sulfur. The conducted scientific research has shown that the activation of phosphorite in the system with a carbamide solution in the presence of sulfur, the part of PO absorbed by plants in the phosphorite, leads to an increase in the level of decarbonization, and the sulfur in the mixture goes into a completely hydrophilic state
NEW FORMS OF EXISTENCE: A PHILOSOPHICAL UNDERSTANDING OF DIGITAL IMMORTALITY AND ITS CONSEQUENCES
Authors: Сметана Владимир Васильевич
Published: January 2025

Данная статья посвящена философскому исследованию новых форм существования, которые могут возникнуть в результате развития цифровых технологий, в частности, в контексте цифрового бессмертия и трансгуманизма. В работе анализируются философские аспекты виртуальной реальности, искусственного интеллекта и трансгуманизма, а также их влияние на понимание человека, реальности и будущего. Особое внимание уделяется онтологическим и эпистемологическим вопросам, связанным с виртуальной реальностью и гипотезой симуляции. Рассматривается проблема различения реальности и симуляции, а также философские импликации возможности того, что наш мир является компьютерной симуляцией. В контексте искусственного интеллекта (ИИ) анализируются проблемы сознания, идентичности и гибридных форм жизни. Рассматриваются этические и экзистенциальные вызовы, связанные с интеграцией человеческого сознания с искусственным интеллектом, а также перспективы развития ИИ и его влияние на человечество. Статья представляет собой междисциплинарное исследование, объединяющее философию, этику, футурологию и философию технологий. Она вносит вклад в развитие философии сознания, онтологии, этики и философии технологий, а также способствует осмыслению перспектив человечества в эпоху цифровых технологий и развития искусственного интеллекта

This article is devoted to the philosophical study of new forms of existence that may arise as a result of the development of digital technologies, in particular, in the context of digital immortality and transhumanism. The work analyzes the philosophical aspects of virtual reality, artificial intelligence and transhumanism, as well as their impact on the understanding of man, reality and the future. Particular attention is paid to the ontological and epistemological issues related to virtual reality and the simulation hypothesis. The problem of distinguishing reality from simulation is considered, as well as the philosophical implications of the possibility that our world is a computer simulation. In the context of artificial intelligence (AI), the problems of consciousness, identity and hybrid forms of life are analyzed. Ethical and existential challenges associated with the integration of human consciousness with artificial intelligence are considered, as well as the prospects for the development of AI and its impact on humanity. The article is an interdisciplinary study that combines philosophy, ethics, futurology and the philosophy of technology. It contributes to the development of the philosophy of consciousness, ontology, ethics and philosophy of technology, and also helps to understand the prospects of humanity in the era of digital technologies and the development of artificial intelligence
IMPORTANCE OF THE LABORATORY PRODUCTION CONTROL PROGRAM FOR IDENTIFICATION OF THE SAFETY LEVEL
Authors: Дягилева Дарья Андреевна
Published: January 2025

В статье изучено значение идентификации уровня опасности процессов и объектов в соответствии с программой производственного контроля. Исследовано функционирование лабораторной деятельности с полным соблюдением установленных мер, методик и структуры в рамках макрообразующего процесса, состоящего из отдельных подпроцедур со специфическими входными/выходными параметрами, ресурсным обеспечением и алгоритмами управления

The article studies the importance of identifying the hazard level of processes and objects in accordance with the production control program. The functioning of laboratory activities with full compliance with established measures, methods and structure within the framework of the macro-forming process, consisting of individual subprocedures with specific input/output parameters, resource provision and control algorithms, is studied
GENERAL ONTOLOGICAL GROUNDS OF MATERIAL OBJECTS OF THE SURROUNDING WORLD
Authors: Карпин Владимир Александрович , Шувалова Ольга Ивановна
Published: January 2025

В основании любых научных исследований должна лежать общенаучная картина мира, которая характеризуется историческим динамизмом. Основой научного знания всегда считалось открытие различных законов. Но для полноценного теоретического знания этого уровня оказалось явно недостаточно. Важнейшим этапом является построение некоторых общих предположений, так называемых принципов, исходя из которых необходимо вывести все вытекающие отсюда следствия. Общими онтологическими основаниями современной теоретической науки являются фундаментальные философские принципы и принципы универсального эволюционизма, объединяющие в единое целое идеи системного и эволюционного подходов

Any scientific research should be based on a general scientific picture of the world, which is characterized by historical dynamism. The discovery of various laws has always been considered the basis of scientific knowledge. But this level was clearly not enough for a full-fledged theoretical knowledge. The most important stage is the construction of some general assumptions, the so-called principles, based on which it is necessary to deduce all the consequences that follow from this. The general ontological foundations of modern theoretical science are the fundamental philosophical principles and principles of universal evolutionism, combining the ideas of systemic and evolutionary approaches into a single whole
PURE CULİNARY PHRASEOLOGY
Authors: Мамедзаде Алмаз Темур кызы
Published: January 2025

В языкознании фразеологизмы объединяются в тематические группы в разных областях в зависимости от содержания, выраженного в них словами. Фразеологизмы, связанные с поварской профессией азербайджанского языка, входят в группу фразеологизмов, сформированных на основе определенных профессиональных сфер. Помимо кулинарной фразеологии здесь приведены и другие профессиональные группы фразеологизмов и примеры, существующие в языке. Кулинарная фразеология делится на исконно кулинарную фразеологию и кулинарную фразеологию используемой совместно с другими по содержанию. Подчеркивается, что кулинарная фразеология выражает семантику, связанную с питанием. Актуальностью и научной новизной темы является вопрос изучения фразеологии по тематическим группам, что является одной из проблем фразеологии азербайджанского языка, ожидающей точного исследования. Четко обозначены названия нескольких групп профессий, охваченных профессиональной фразеологией, среди них широко обсуждается кулинарная фразеология

Linguistics, phraseological units are combined in thematic groups in different areas depending on the content expressed by the words in them. Phraseology related to the cooking profession of the Azerbaijani language is part of a group of phraseological units formed on the basis of a certain field of profession. In addition to culinary phraseology, other professional- specialty phraseology groups and examples that exist in the language are given here. Culinary phraseology is divided into pure culinary phraseology and culinary phraseology used together with other groups. It is emphasized that culinary phraseology namely conveys the semantics of nutrition. The topic of relevance and scientific novelty is the issue of studying phraseology in thematic groups, which is one of the problems of language phraseology that awaits precise research. He clearly outlined the names of several groups of professions covered by professional phraseology, among them culinary phraseology is widely discussed
ПРИМЕНЕНИЕ НЕЙРОННЫХ СЕТЕЙ ДЛЯ АВТОМАТИЗАЦИИ РАЗРАБОТКИ ТЕХНОЛОГИЧЕСКИХ ПРОЦЕССОВ В ПРИБОРОСТРОЕНИЕ
Authors: Лаптев Александр Александрович , Третьяков Сергей Дмитриевич
Published: January 2025

Целью данной статьи является разработка нового способа поиска деталей-аналогов в информационно-поисковых системах технологического назначения (ИПС ТН) на предприятиях изготавливающие детали приборостроения. Предложенный способ повысит эффективности технологической подготовки производства за счет использования нейронных сетей
ФИЗИЧЕСКАЯ КУЛЬТУРА И СПОРТ В СИСТЕМЕ ФОРМИРОВАНИЯ ЛИЧНОСТИ СТУДЕНЧЕСКОЙ МОЛОДЕЖИ
Authors: Легова Екатерина Сергеевна
Published: January 2025

В статье рассмотрена роль физической культуры и спорта в формировании основных качеств и свойств личности. Установлено, что занятия физическими упражнениями, спортом, если они педагогически правильно организованы, дают возможность существенно и целенаправленно влиять на формирование гармонично развитой личности

The article examines the role of physical culture and sports in the formation of basic qualities and personality traits. It has been established that physical exercises and sports, if they are pedagogically properly organized, make it possible to significantly and purposefully influence the formation of a harmoniously developed personality
АНАЛИЗ РЕЗУЛЬТАТОВ ДИАГНОСТИЧЕСКОГО ТЕСТИРОВАНИЯ ПО ОСНОВАМ БЕЗОПАСНОСТИ ЖИЗНЕДЕЯТЕЛЬНОСТИ ПЕРВОКУРСНИКОВ ЕСТЕСТВЕННО-ГЕОГРАФИЧЕСКОГО ФАКУЛЬТЕТА ТУВГУ
Authors: Доржу Урана Валериевна
Published: January 2025

В статье даны результаты диагностического тестирования студентов-первокурсников, поступивших в 2024 -2025 уч.г. на естественно-географический факультет Тувинского государственного университета. В результате выявлено, что уровень знаний студентов первого курса по дисциплине «Основы безопасности жизнедеятельности», полученных на базе среднего общего образования, низкий

The article presents the results of diagnostic testing of first-year students enrolled in the 2024-2025 academic year at the Faculty of Natural Geography of Tuvan State University. As a result, it was revealed that the level of knowledge of first-year students in the discipline "Fundamentals of life safety", obtained on the basis of secondary general education, is low
Transformações no planejamento pedagógico e no desenvolvimento profissional
Authors: Roveda Gabriele Maidano , Freitas da Silva João Paulo , Sawitzki Rosalvo Luis
Published: January 2025

Este artigo analisa o impacto do Programa Residência Pedagógica (PRP) como uma prática de Formação Continuada (FC) colaborativa no planejamento pedagógico e no desenvolvimento profissional dos professores preceptores do núcleo Educação Física da Universidade Federal de Santa Maria. Embora a Formação Inicial seja objetivo do PRP, partimos da hipótese de que o Programa apresenta e possibilita mudanças no trabalho pedagógico desses profissionais. Por meio de Entrevistas Semiestruturadas realizadas com dois preceptores, o estudo revelou que o PRP teve um impacto significativo, proporcionando aos docentes a oportunidade de revisitar o Projeto Político-Pedagógico da escola, um documento frequentemente negligenciado. Os resultados destacam o efeito positivo do PRP em promover uma abordagem reflexiva e colaborativa na prática docente, evidenciando a importância para a FC.
Conectividade e aprendizagem
Authors: Ana Lucia Muniz Baptista Uchoa  , Monteiro Patricia Ortiz
Published: January 2025

O objetivo da pesquisa foi analisar a conectividade e as experiências no processo educativo dos estudantes do Ensino Médio durante a pandemia do Covid-19. Para isso, foram realizados questionários e desenhos com alunos de Ensino Médio, das redes pública e particular, que compartilharam suas vivências nesse período. A análise de conteúdo do material coletado revelou que as Tecnologias Digitais de Informação e Comunicação (TDIC) se tornaram ferramentas essenciais que possibilitaram a comunicação remota. Conclui-se que as TDIC promoveram a continuidade do processo educativo, sendo valorizadas como recurso pedagógico inovador.
Generative Artificial Intelligence in Anatomic Pathology
Authors: Brodsky Victor , Ullah Ehsan , Bychkov Andrey , Song Andrew H. , Walk Eric E. , Louis Peter , Rasool Ghulam , Singh Rajendra S. , Mahmood Faisal , Bui Marilyn M. , Parwani Anil V.
Published: January 2025

Context.—

Generative artificial intelligence (AI) has emerged as a transformative force in various fields, including anatomic pathology, where it offers the potential to significantly enhance diagnostic accuracy, workflow efficiency, and research capabilities.

Objective.—

To explore the applications, benefits, and challenges of generative AI in anatomic pathology, with a focus on its impact on diagnostic processes, workflow efficiency, education, and research.

Data Sources.—

A comprehensive review of current literature and recent advancements in the application of generative AI within anatomic pathology, categorized into unimodal and multimodal applications, and evaluated for clinical utility, ethical considerations, and future potential.

Conclusions.—

Generative AI demonstrates significant promise in various domains of anatomic pathology, including diagnostic accuracy enhanced through AI-driven image analysis, virtual staining, and synthetic data generation; workflow efficiency, with potential for improvement by automating routine tasks, quality control, and reflex testing; education and research, facilitated by AI-generated educational content, synthetic histology images, and advanced data analysis methods; and clinical integration, with preliminary surveys indicating cautious optimism for nondiagnostic AI tasks and growing engagement in academic settings. Ethical and practical challenges require being addressed by rigorous validation, prompt engineering, federated learning, and synthetic data generation to help ensure trustworthy, reliable, and unbiased AI applications. Generative AI can potentially revolutionize anatomic pathology, enhancing diagnostic accuracy, improving workflow efficiency, and advancing education and research. Successful integration into clinical practice will require continued interdisciplinary collaboration, careful validation, and adherence to ethical standards to ensure the benefits of AI are realized while maintaining the highest standards of patient care.
The Impact of Global Climate Change on the Species Composition of Agricultural Crops in the Lori Region
Authors: Vardanyan Zaruhy , Ghazaryan Armine , Babelyan Arevik
Published: January 2025

Key words: climate change, crops, tomato, broccoli, lettuce, brussels sprouts, crop species composition

Over the last 50 years, under the changes of climate conditions, the species composition of crops grown in the agricultural areas of the Lori region has included various types of tomatoes (Lycopersicum esculentum Mill), lettuce (Lactuca sativa L.), Brussels sprouts (Brassica oleracea convar. oleracea var. gemmifera), broccoli (B. oleracea convar. botrytis var. italica), and kohlrabi (Brassica oleracea var. gongylodes).
The study focused on the non-traditional crops of red and yellow tomatoes (Lycopersicum esculentum Mill) grown in the Lori region under the changes of climate conditions. The concentration and content of chlorophyll a and b, as well as carotenoids, were studied in the fruits of the examined plants. Samples were taken from different locations in the Lori region: Test Site 1 – Vanadzor town, Test Site 2 – Geghasar village, and Test Site 3 – Odzun village.
The concentration and the amount of carotenoids in the fruits of the red tomato plants were lowest in the samples from Test Site 3 and highest in the samples from Test Site 1. In the yellow tomato fruit flesh, the concentration of chlorophyll Ca and chlorophyll Cb was highest in the fruit flesh of the tomatoes from Test Site 3 and lowest in the tomatoes from Test Site 1.
The concentrations and contents of chlorophylls and carotenoids are inversely proportional.
On Atypical Solutions of Some Typical and Atypical Problems Encountered in the School Mathematics Course
Authors: Nikoghosyan Gagik
Published: January 2025

Key words: fraction, divisibility, equation, inequality, interval method, logic

Due to the fact that both interdisciplinary and intradisciplinary connections are not fully reflected in school mathematics courses, with an emphasis on new forms of organizing learning, insufficient attention is currently paid to improving the content of learning and thereby increasing efficiency. This work’s scientific and pedagogical novelty lies in its identification of atypical (non-traditional) solutions to a variety of typical and atypical problems encountered in the school mathematics course. It also highlights common mistakes made when solving typical and atypical problems and suggests potential workarounds.
The terms “typical problem” and “typical solution” as well as “atypical problem” and “atypical solution” will be briefly explained in this article. After that, we will emphasize the specific classes of typical problems (arithmetic problems, equations, inequalities, etc.) and provide methodological guidance on how to solve the problems' primary challenges and steer clear of common blunders. For each class of problems, we will highlight the potential successful uses of intra-subject connections in the school mathematics course. In addition, we will briefly discuss common ways used to solve these kinds of problems.
We will also address a number of uncommon mixed situations at the end of the paper, for which we will provide alternative methods that deviate from the “traditional” solutions.
Virtual Destructors and the Absence of Virtual Constructors in C++: Analysis and Examples
Authors: Ohanyan Heghine
Published: January 2025

Key words: polymorphism, memory leak, memory management, smart pointers, std::shared_ptr, virtual function table (vtable)

C++ is a powerful programming language extensively utilized in both system and application programming; particularly in scenarios where performance and resource control are critical. A key aspect of C++ is its memory and resource management, especially in the context of inheritance and polymorphism. This article provides an in-depth analysis of the use of virtual destructors and explains why constructors cannot be virtual in C++. Code examples illustrate common mistakes arising from improper destructor usage and demonstrate correct implementation approaches. Virtual destructors are essential in polymorphic class hierarchies for proper resource deallocation and prevention of memory leaks. In contrast, constructors cannot be virtual due to the specific mechanics of object initialization and the functioning of the virtual table (vtable). The article also explores modern memory management tools, such as smart pointers (std::shared_ptr, std::uniqueptr), and their role in ensuring safe and efficient resource management within polymorphic contexts. This material is meant for the developers seeking to deepen their understanding of memory management in C++, particularly in complex polymorphic hierarchies.
Anmeldung zum Vernetzungsworkshop Infra Wiss Blogs
Authors: Ochsner Catharina , Pampel Heinz
Published: January 2025

Im Rahmen des Projekts “Infra Wiss Blogs” veranstalten wir am 06.12.2024 einen ersten Vernetzungsworkshop für bloggenden Forschende und Mitarbeitende aus Infrastruktureinrichtungen. Ziel ist es, erste Erfahrungen der verschiedenen Stakeholder zu teilen und ihren Austausch zu fördern. Des Weiteren werden wir erste Ergebnisse unserer Bestandsaufnahme deutscher Wissenschaftsblogs präsentieren.
Going NUTS: A Step-by-Step Guide to Adaptive Hamiltonian Sampling in R
Authors: Castillo-Aguilar Matías
Published: January 2025

Introduction

Remember MCMC from our series on these algorithms? Good times. We wandered through probability space like tourists with outdated maps, occasionally stumbling upon the good parts of the posterior. Then came Hamiltonian Monte Carlo (HMC), which, let’s be honest, felt like finally getting a GPS. We could

actually

explore the posterior, using gradients to guide our journey. It was efficient! It was elegant!
Ausblicke auf die zukünftige Infrastruktur für wissenschaftliche Blogs in Deutschland
Authors: Ochsner Catharina , Höfting Jonas , Pampel Heinz
Published: January 2025

Am 6. Dezember 2024 haben wir den ersten Workshop unseres von der Deutschen Forschungsgemeinschaft (DFG) geförderten Projekts Infra Wiss Blogs (Ochsner and Pampel 2024) veranstaltet.