bluuebunny/crossref_metadata_2025 huggingface dataset:
The Sleeping Dogs Method to Overcome Children’s Resistance to EMDR Therapy: A Case Series
Authors: Struik Arianne
Published: November 2018

This article provides three case descriptions to demonstrate the use of the “Sleeping Dogs” method to engage children who initially refused to participate in EMDR therapy. The metaphor “sleeping dogs” refers to traumatic memories that children refuse to or cannot discuss; by waking up the “sleeping dogs,” traumatic memories become accessible and treatable. Children in the cases discussed displayed severe symptoms and refused to discuss memories of traumatic experiences. All resided in a residential facility and their symptoms were preventing transition into foster care. Case 1 (age 6) displayed increasingly violent behavior. He witnessed his father kill his mother and was the crown witness in his father’s trial, which isolated him from his family. Case 2 (age 3), was abused by her biological family, and experienced foster placement breakdown. Case 3 (age 6) was abused by her mother, yet idolized her and denied past abuse. This article describes how the Sleeping Dogs method was applied in each case, created stabilization, and led to engagement in EMDR, in which trauma memories were processed. After treatment all children transitioned into foster care. The cases demonstrate the benefits of involving (extended) family members, even when they have abused or neglected the child and may have little or no contact with them, and when reunification is no option. The implications for utilizing the Sleeping Dogs method to engage chronically traumatized children in trauma-focused therapy are discussed.
Trust and Attunement-Focused EMDR With a Child
Authors: Rathore Helen E.
Published: November 2018

This qualitative case study explores using eye movement desensitization and reprocessing (EMDR) therapy informed by attachment and neuroscience research about the importance of safety (trust) and relationship (attunement). This was chosen to enable a young child to create vital positive neural networks and process early trauma while remaining within the window of receptivity, despite issues of avoidance and control. A single case study design was used with a 5-year-old child who experienced early traumas. Observable symptoms included separation anxiety, avoidance, compromised motor skills, and compromised speech. Data were obtained from carer, child, and teacher report, notes, observations, case file, ratings of emotions, and behaviors. The data were explored for outcome data points, validity, and protocol adherence. Key findings were that EMDR used with attunement and trust-building strategies appeared to support developmental progress while facilitating pervasive posttraumatic growth. EMDR appears to offer appropriate opportunities for incorporating neuroscience and attachment research in order to facilitate trauma processing. Future research into EMDR storytelling procedures and possible causative relationships between trust-building and attunement with neurodevelopmental markers would be a possible next step.
The Child-Centered EMDR Approach: A Case Study Investigating a Young Girl’s Treatment for Sexual Abuse
Authors: Swinden Colleen
Published: November 2018

This article seeks to address the underrepresented area of eye movement desensitization and reprocessing (EMDR) treatment for sexually abused children. It presents the child-centered EMDR approach–a new protocol derived from Klaff (2016). This approach is built on Shapiro’s Adaptive Information Processing model and assumes that a successful outcome can be achieved without directly processing memories of the abuse since children have the ability to open channels of association to uncover, process, and resolve emotional trauma relating to the abuse. Instead of focusing on traumatic memories, the treatment targets whatever current concerns the child presents, as it is thought that these concerns may provide a pathway to covert and possibly unconscious issues. This approach is tested with a case study, which explores its use with a 9-year-old girl who presented with emotional triggers originating from sexual abuse by her biological father. She received six sessions addressing memories of being taunted by other children and of her father using drugs, but her memories of the sexual abuse were not directly addressed. Following treatment, her scores on the Child Report of Post-Traumatic Symptoms (CROPS) and Parent Report of Post-Traumatic Symptoms (PROPS) decreased to nonclinical levels, with results maintained 2 months later at follow-up. The promising results suggest the value of future research to further test this approach.
Optical, Dielectric and Magnetic Properties of La1-xNdxFeO3 Powders and Ceramics
Authors: Głuchowski Paweł , Oganisian Karen , Tomala Robert , Łukowiak Anna , Karpinsky Dmitry , Alikin Denis , Kholkin Andrei , Stręk Wiesław
Published: November 2018

Nanocrystalline La1-xNdxFeO3 powders with different concentrations of Nd3+ have been synthesized by modified Pechini method. Their structure was studied by X-ray powder diffraction (XRD). Further, La1-xNdxFeO3 nanoceramics were prepared by high pressure sintering technique. The luminescence spectra of the powders were investigated as a function of concentration of active dopant to check the possible energy transfers observed due to Nd3+ concentration changes. The electrical and magnetic properties of the powders and ceramics were investigated to determine the effect of Nd3+ doping on the dielectric permittivity and magnetization in the wide frequency range.
A Green Process for the Extraction and Purification of Hesperidin from Mexican Lime Peel (Citrus aurantifolia Swingle) Extendible to Citrus Genus
Authors: Padilla de la Rosa José Daniel , Ruiz-Palomino Priscilla , Guatemala-Morales Guadalupe M. , García-Fajardo Jorge A. , Sandoval-Fabián Georgina C. , Arriola-Guevara Enrique
Published: November 2018

The processing of Mexican limes generates great amounts of peel as a byproduct. Lime peel is mainly rich in the flavonoid hesperidin, whose bioactivity is oriented mainly to cardiovascular diseases and cancer. The purpose of this work was to develop a green process for the extraction and purification of hesperidin from Mexican lime peel. The extraction of hesperidin was investigated on a laboratory scale by varying the solvent composition and the solid-to-solvent ratio. The best conditions (solid-to-solvent ratio of 0.33 g/mL and 60% ethanol) were used for the extraction of hesperidin in a pilot scale (Volume = 20 L). The kinetics of the extraction was studied to find the maximum hesperidin concentration at 100 min. The concentrated extract had a hesperidin content of 0.303 mg/mL. Next, a purification process using adsorption resins was assessed. Through static tests, it was determined that higher adsorption efficiencies were achieved with the EXA-118 resin and diluted extract (4:6 ratio with 10% DMSO). Finally, the adsorption of hesperidin from the diluted extract (hesperidin concentration of 0.109 mg/mL) was carried out at 25 °C in a column packed with 80 mL of EXA-118 resin. The mean recovery efficiency of hesperidin from the extract was almost 90%.
Establishment and Application of an Evaluation System for the Sustainable Development of Subway Traffic
Authors: Geng Dong-Yang , Vojtasik Karel
Published: November 2018

According to the characteristics of the sustainable development of subway traffic, the establishment process of an evaluation index system is determined, and the evaluation method and basis are defined. The evaluation index system is established from the aspects of subway traffic sustainability, economic sustainability and urban coordination sustainability. The comprehensive evaluation method of the analytic hierarchy process (AHP) model is used to calculate the weights of comprehensive evaluation indexes at each level. Finally, the sustainable development model of Shijiazhuang subway traffic is evaluated. The results show that the proposed evaluation system and model reflect the degree of sustainable development of subway traffic and can be used for reference in the evaluation of regional subway traffic sustainable development.
Circulating Tumor Cells Develop Resistance to TRAIL-Induced Apoptosis through Autophagic Removal of Death Receptor 5: Evidence from an In Vitro Model
Authors: Twomey Julianne D. , Zhang Baolin
Published: November 2018

Circulating tumor cells (CTCs) in the peripheral blood are the precursors to distant metastasis but the underlying mechanisms are poorly understood.  This study aims at understanding the molecular features within CTCs in relation to their metastatic potential.  Using in vitro CTC models, in which breast cancer cell lines are cultured in non-adherent conditions simulating the microenvironment in the blood stream, we found that suspension culture resulted in resistance to TNF-related apoptosis inducing ligand (TRAIL)-mediated cell death. Such a resistance was directly correlated with a reduction in surface and total levels of DR5 protein. In the non-adherent state, cells underwent rapid autophagic flux characterized by an accumulation of autophagosome organelles. Notably, DR5 was translocated to autophagosomes and underwent lysosomal degradation.  Our data suggest that CTCs may evade TNF cytokine mediated immune surveillance through downregulation of DR expression. The data warrants further studies in cancer patients to find the status of DRs and other molecular features within primary CTCs in relation to disease progression or chemoresistance.
Polyamine Homeostasis in Snyder-Robinson Syndrome
Authors: Murray Stewart Tracy , Dunworth Matthew , Foley Jackson R. , Schwartz Charles E. , Casero, Jr. Robert A.
Published: November 2018

Loss-of-function mutations of the spermine synthase gene (SMS) result in Snyder-Robinson Syndrome (SRS), a recessive X-linked syndrome characterized by intellectual disability, osteoporosis, hypotonia, speech abnormalities, kyphoscoliosis, and seizures. As SMS catalyzes the biosynthesis of the polyamine spermine from its precursor spermidine, SMS deficiency causes a lack of spermine with an accumulation of spermidine. As polyamines, spermine and spermidine play essential cellular roles that require tight homeostatic control to ensure normal cell growth, differentiation, and survival. Using patient-derived lymphoblast cell lines, we sought to comprehensively investigate the effects of SMS deficiency on polyamine homeostatic mechanisms including polyamine biosynthetic and catabolic enzymes, derivatives of the natural polyamines, and polyamine transport activity. In addition to decreased spermine and increased spermidine in SRS cells, ornithine decarboxylase activity and its product putrescine were significantly decreased. Treatment of SRS cells with exogenous spermine revealed that polyamine transport was active, as the cells accumulated spermine, decreased their spermidine level, and established a spermidine-to-spermine ratio within the range of wild type cells. SRS cells also demonstrated elevated levels of tissue transglutaminase, a change associated with certain neurodegenerative diseases. These studies form a basis for further investigations into the leading biochemical changes and properties of SMS-mutant cells that potentially represent therapeutic targets for the treatment of Snyder-Robinson Syndrome.
Zinc: A Necessary Ion for Mammalian Sperm Fertilization Competency
Authors: Kerns Karl , Zigo Michal , Sutovsky Peter
Published: November 2018

The importance of zinc for male fertility only emerged recently, propelled in part by consumer interest in nutritional supplements containing ionic trace minerals. Here, we review the properties, biological roles and cellular mechanisms that are relevant to zinc function in the male reproductive system, survey available peer-reviewed data on nutritional zinc supplementation for fertility improvement in livestock animals and infertility therapy in men, and discuss recently discovered signaling pathways involving zinc in sperm maturation and fertilization. Emphasis is on the zinc-interacting sperm proteome and its involvement in the regulation of sperm structure and function, from spermatogenesis and epididymal sperm maturation to sperm interactions with the female reproductive tract, capacitation, fertilization and embryo development. Merits of dietary zinc supplementation and zinc inclusion into semen processing media are considered with livestock artificial insemination (AI) and human assisted reproductive therapy (ART) in mind. Collectively, the currently available data underline the importance of zinc ions for male fertility, which could be harnessed to improve human reproductive health and reproductive efficiency in agriculturally important livestock species. Further research will advance the field of sperm and fertilization biology, provide new research tools, and ultimately optimize semen processing procedures for human infertility therapy and livestock AI. 
Tying Together Multiscale Calculations for Charge Transport in P3HT: Structural Descriptors, Morphology, and Tie-Chains
Authors: Miller Evan D. , Jones Matthew L. , Jankowski Eric
Published: November 2018

Evaluating new, promising organic molecules to make next-generation organic optoelectronic devices necessitates the evaluation of charge carrier transport performance through the semi-conducting medium. In this work, we utilize quantum chemical calculations (QCC) and kinetic Monte Carlo (KMC) simulations to predict the zero-field hole mobilities of ~100 morphologies of the benchmark polymer poly(3-hexylthiophene), with varying simulation volume, structural order, and chain-length polydispersity. Morphologies with monodisperse chains were generated previously using an optimized molecular dynamics force-field and represent a spectrum of nanostructured order. We discover that a combined consideration of backbone clustering and system-wide disorder arising from side-chain conformations are correlated with hole mobility. Furthermore, we show that strongly interconnected thiophene backbones are required for efficient charge transport. This definitively shows the role "tie-chains" play in enabling mobile charges in P3HT. By marrying QCC and KMC over multiple length- and time-scales, we demonstrate that it is now possible to routinely probe the relationship between molecular nanostructure and device performance.
Authentic Student Laboratory Classes in Science Education
Authors: Schulte Jurgen
Published: November 2018

The traditional hands-on nature in science laboratory classes creates a sense of immediacy and presence of authenticity in such learning experiences. The handling of physical objects in a laboratory class and the immediate responses provided by the experiments are certainly real-live observations, yet may be far from instilling an authentic learning experience in students. This paper explores the presence of authenticity in hands-on laboratory classes in introductory science laboratories. With our own laboratory program as backdrop we introduce four general types of hands-on laboratory experiences and assign degrees of authenticity according the processes and student engagement associated with them. In that course, we present a newly developed type of hands-on experiment which takes a somewhat different view of the concept of hands-on in a laboratory class. A proxemics-based study of teacher-student interactions in the hands-on laboratory classes presents us with some insights into the design of the different types of laboratory classes and the pedagogical presumptions we made. A step-by-step guide on how to embed industry engagement in the curriculum and the design of an authentic laboratory program is presented to highlight some minimum requirement for the sustainability of such program and pitfalls to avoid.
Demand Response Readiness in Retail Stores: DR Control Preferences, Stakeholder Engagement, and Cross-National Differences
Authors: Ma Zheng , Kuusinen Kati , Kjærgaard Mikkel Baun , Jørgensen Bo Nørregaard
Published: November 2018

Retail buildings can provide energy flexibility to the grid with the possibility of load shifting and building automation systems. Demand response is a collective innovation in the smart grid domain. Various stakeholders should be involved in the demand response activities to ensure the success. The owners or senior management of retail buildings need to consider the stakeholders who are directly influenced by the demand response participation, e.g. customers and employees. Meanwhile, demand response activities are influenced by various factors, such as energy market structure, policy, etc. Therefore, this paper investigates the demand response readiness for retail buildings with three aspects: energy control preferences, stakeholder engagement, and cross-national differences. A questionnaire is designed and collected with store managers in Denmark (N=51) and the Philippines (N=36). The result shows that: 1) retail stores are much readier to participate in the implicit demand response by manual energy control compared to the utility control or building automation. Meanwhile, store managers have significant concerns about business activities and indoor lighting compared to other aspects; 2) the statistically significant influential factors for retail stores to participate in the demand response are related to whether the DR participation matches the company goals, influences business operation,  and whether retail stores are lack of related knowledge; 3) retail stores believe that stakeholders should be informed about the DR activities but not involved in; 4) there are significant differences regarding the energy control preferences and concerns between retail stores in Denmark and the Philippines, but no significant difference regarding the stakeholder engagement.
Demographic Diversity of Food Intake and Prevalence of Kidney Stone Diseases in Indian Continent
Authors: Guha Manalee , Banerjee Hritwick , Mitra Pubali , Das Madhusudan
Published: November 2018

Food intake plays a pivotal role of human growth, which necessarily contributes 45% of global economy and wellbeing in general. Consumption of balanced food is elementary for overall good health while a shift of equilibrium can lead to malnutrition, prenatal death, obesity, osteoporosis and bone fractures, coronary heart diseases (CHD), idiopathic hypercalciuria, diabetes and many more. Though CHD, osteoporosis, malnutrition, obesity are being classified thoroughly in the literature, there are fragmented findings in the regime of kidney stone diseases (KSD) and the correlation with food intake therein. KSD associated with hematuria and renal failure poses an increasing threat to the healthcare and global economy while its emergence of Indian populations is being affected with multi-factorial urological disorder resulting from several factors. In this realm, epidemiological, biochemical, macroeconomic situations been portrayed when food intake is also a paramount importance which rarely been forecasted. Hence, in this article we will be reviewing the corollary connotation with diverse food consumption and the efficacy it plays in KSD extrapolating in Indian context.
Comparing Supervised Machine Learning Strategies and Linguistic Features to Search for Very Negative Opinions
Authors: Almatarneh Sattam , Gamallo Pablo
Published: November 2018

In this paper, we examine the performance of several classifiers in the process of searching for very negative opinions. More precisely, we do an empirical study that analyzes the influence of three types of linguistic features (n-grams, word embeddings, and polarity lexicons) and their combinations when they are used to feed different supervised machine learning classifiers: Support Vector Machine (SVM), Naive Bayes (NB), and Decision Tree (DT).
PERKEMBANGAN PERAKITAN VARIETAS DAN TEKNIK BUDI DAYA JAGUNG ANTIOKSIDAN SEBAGAI PANGAN FUNGSIONAL
Authors: HG M Yasin , Talanca A. Haris , Mejaya M Jana
Published: November 2018

ABSTRAK

Jagung antioksidan mengandung beta karoten pada endosperm yang bermanfaat untuk kesehatan, antara lain dapat mencegah buta dini (rabun/katarak), kerontokan rambut, memperkuat jaringan tubuh, dan mencegah gizi buruk pada anak balita. Kementerian Pertanian telah melepas tiga varietas jagung antioksidan kaya beta karoten, dua dari jenis bersari bebas (varietas Provit A1 dan Provit A2) dan satu dari jenis hibrida (varietas Bima Provit A1) masing-masing dengan kadar beta karoten 155,3-281,6% lebih tinggi dari jagung biasa. Potensi hasil jenis bersari bebas dapat mencapai 7,36 t/ha dan jenis hibrida 9,85 t/ha. Budi daya jagung antioksidan sama dengan jagung biasa. Aspek yang perlu mendapat perhatian adalah isolasi jarak tanaman, minimal 300 m, dan isolasi waktu tanam 3 minggu setelah tanam dengan tanaman jagung biasa. Hal ini diperlukan untuk menghindari xenia effect, yaitu pengaruh tepungsari jagung biasa yang menyerbuki jagung antioksidan sehingga kadar antioksidannya akan menurun dan statusnya kembali sama dengan jagung biasa. Hasil panen dapat dijadikan bahan baku industry berbagai makanan olahan bergizi tinggi. Pengembangan jagung antioksidan, terutama di Kawasan Timur Indonesia perlu peran pemerintah setempat dalam upaya mempercepat adopsi oleh petani.

Kata kunci: Jagung, antioksidan, beta karoten, pangan fungsional

 

ABSTRACT

Antioxidant maize contains beta carotene in the endosperm that is beneficial for health, such as can prevent early blindness (blindness / cataract), hair loss, strengthen body tissues, and prevent malnutrition in children under five. The Ministry of Agriculture has released three varieties of beta-carotene-rich antioxidant maize, two of the free-range (Provit A1 and Provit A2) varieties and one of the hybrid varieties (Bima Provit A1) each with carotene beta levels of 155.3 to 236.6 % higher than ordinary corn. The potential of free pollen type yield can reach 7.36 t / ha and hybrid type 9.85 t / ha. The cultivation of antioxidant corn is the same as ordinary corn. Aspects that need attention are isolation of plant spacing, at least 300 m, and isolation of planting time 3 weeks after planting with ordinary corn crops. This is necessary to avoid the xenia effect, which is the effect of ordinary corn corn that pollinate antioxidant corn so that its antioxidant levels will decrease and its status is the same as ordinary corn. Yields can be used as industrial raw materials of various highly processed nutritious foods. Development of antioxidant maize, especially in Eastern Indonesia needs the role of local government in an effort to accelerate adoption by farmers.

Keywords: Maize, antioxidant, beta caroten, functional food.
Volumetric Efficiency Evaluation of Sucker-Rod-Pumping Applications Performed on a Pump Testing Facility
Authors: Kochtik Daniel , Langbauer Clemens
Published: November 2018

Low oil prices at the stock market and high water cuts of the produced fluid, force the oil companies to continuously optimize their facilities to meet the actual requirements regarding efficiency. One step in the chain of oil production from the reservoir to the customer is the optimization of artificial lift systems in mature oil fields. Nowadays sucker rod pumping systems are still by far the most frequently used artificial lift systems. These pumps represent an efficient and simple way to increase the oil production. On the one hand from the technical point of view, this system is easily adjustable to changing operating conditions. On the other hand, its economic footprint is, compared to other artificial lift methods, relatively small.

Due to the huge number of installed units, an energy efficient and failure resistant design is essential. A deep understanding of the actual process during pumping is significant for continuously optimizing the pumping system. This paper presents the evaluation of volumetric efficiency tests, performed at the Pump Testing Facility (PTF) at the Montanuniversität Leoben, under various operating conditions and the investigating of the related physical effects.

Slippage, one of the most influencing factors of volumetric efficiency, is highly dependent on the differential pressure generated by the pump plunger, but as well on the strokes per minute. The results of various attempts that were performed to get a detailed understanding of the internal losses (slippage volume) during the pumping operation are shown. Two different pump types, namely the standard sucker rod pump (SRP) and the sucker rod anti-buckling system pump (SRABS) are tested with different fluid types. Both pumps were operated with various speeds and under different pressure conditions. The test results are compared with existing slippage models. The comparison indicates that most of the existing slippage models underpredict the slippage rate by a significant fraction. Therefore, it is necessary to do additional and more detailed tests to be able to define a more precise model to predict slippage losses during pumping operations.
Enhanced Sucker Rod Pumping Model: A Powerful Tool for Optimizing Production, Efficiency and Reliability
Authors: Di Tullio Matteo Tommaso , Marfella Ferdinando
Published: November 2018

As the oil industry begins to emerge from one of the worst downturns in decades, companies need to operate in a market of unstable oil prices that the upstream oil and gas industry continues to face. New innovative, sustainable, and disruptive artificial lift technologies are the cost-effective way seek by the operators to minimize risks, maximize production, and remain profitable on the market.

In wells with sucker rod-lift systems, elastic beam vibrations induced by downhole pump operation are the main source for premature rod string failure and tubing wear. A completely new steady-state vibrations model for rod string assemblies has been implemented to understand and predict the rod/tubing wear damage phenomenon responsible for half of all well failure events in beam pump operation and most expensive routine well servicing cost.

This paper introduces the developed model to enhance prediction of mechanical rod string dynamics during pumping operation, and delivers next generation analytics solution to be utilized for artificial intelligence, industrial internet of things, real-time monitoring, and automation of rod pumping systems.

The model works on a set of forced Duffing-like differential equations with cubic non-linearity and damping, these generated discretizing beam elastic behavior using vibration mode basis. Model simulation runs in the time domain numerically capture relevant axial-flexural dynamic forces undergone by rod string during up and down stroke phases, as well as downstroke rod string bending-buckling tendency and its interaction with tubing internal wall.

Some examples show usefulness of the novel model to predict failures and maximize uptime, reduce costs with predictive analytics, and design the optimal rod lift solution in every stage of well life cycle.
Distinct Features of the Self-Concept and the Meaning-Forming Motives of Intellectual Professionals: A Case of Australian and Russian Specialists of Intellectual Labour
Authors: Obukhova Julia V. , Komarovskaya Ekaterina L.
Published: November 2018

Introduction. The authors substantiate the necessity and relevance of studying the features of self-concept and the meaning-forming motives for intellectual labour. The novelty of this study is that a comparative analysis of the particularities of self-concept and the meaning-forming motives of the Australian and Russian specialists of intellectual labour is carried out for the first time.

Methods. The study is based on the survey of 30 Australian and 40 Russian professionals in various fields of intellectual labour, whose average age was 34 years and 36 years old respectively. Psychological testing and content analysis of respondents’ self-descriptions were used as primary methods of research. The questionnaire with open-ended items created by the authors, entitled “Meaning-Forming Motives of Labour Activity – Money”, has been used for data collection. Parametric and nonparametric statistical procedures were carried out in analyses.

Results and Discussion. This section describes the features of cognitive and emotional-evaluative components of self-concept, work-related meaning-forming motives of Australian and Russian professionals in the field of intellectual labour, both men and women. The leading categories in self-descriptions of the respondents are dependent on their nationality and gender. The following features of self-concept were revealed in the study: Australian men describe themselves through their look, Australian women – through their hobbies and friendships, Russian women – through their society status and social environment. The obtained results can be used in the development of a general management system and of training programs for professionals in the field of intellectual labour.
Коллективная память о России ХХ века и ценности разных поколенческих групп
Authors: Baranova Victoria A. , Zhukova Maria O.
Published: November 2018

Введение. Авторами рассматривается актуальность подхода к изучению коллективной памяти с позиций конструкционизма. При изучении коллективной памяти в данном исследовании научные задачи направлены на выявление событийного ряда, который конструирует групповые воспоминания, определяя то, что имеет для одной поколенческой группы современного общества большую значимость, чем для другой. Новизна исследования заключается в выявлении преобладающих ценностей каждой поколенческой группы и характеристике содержания коллективных воспоминаний о России ХХ века с учетом ведущих групповых ценностей.

Методы. В исследовании применяются методы количественного и качественного анализа: ассоциативная методика, методика для выявления ценностей Ш. Шварца, анкета для сравнения России XX века и идеальной России. Выборку исследования составили респонденты разного возраста из различных регионов России, всего 90 человек.

Результаты. Данный раздел включает описание содержания групповых воспоминаний о России ХХ века, групповой структуры преобладающих ценностей, результаты сравнения России ХХ века с идеальной Россией для трех возрастных групп. Содержание воспоминаний о России ХХ века и результаты сравнения России XX века и идеальной России отражают групповую поколенческую специфику: содержание представлено различными событиями; Россия представляется как страной, далекой от идеала, так и оценивается высоко. При исследовании групповых ценностей выявлено, что для каждой поколенческой группы характерна собственная структура.

Обсуждение результатов. Анализ воспоминаний о России ХХ века показал, что их содержание отражает групповую специфику отношения к прошлому. Полученные результаты подтвердили гипотезу о существовании групповых особенностей конструирования коллективных воспоминаний об историческом периоде, что дает возможность определять коллективную память как необходимое свойство социальной группы. В исследовании описан феномен «поколенческой сензитивности», проявляющийся в повышенной чувствительности (восприимчивости) к прошедшим и происходящим событиям представителей разных социальных поколенческих групп.
Carbon Nano-onions: A Valuable Class of Carbon Nanomaterials in Biomedicine
Authors: Giordani Silvia , Camisasca Adalberto , Maffeis Viviana
Published: November 2018

:

The development of nanoscale materials is an important area of research as it provides access
to materials with unique properties that can be applied to improve quality of life. Multi-layer fullerenes,
also known as carbon nano-onions (CNOs) are an exciting class of nanostructures which show great versatility
and applicability. They find applications in several fields of technology and biomedicine. This
review highlights the potential advantages of CNOs for biomedical applications, which include but are
not limited to bioimaging and sensing. Their good biocompatibility renders them promising platforms for
the development of novel healthcare devices.
Human Breast Milk-acquired Cytomegalovirus Infection: Certainties, Doubts and Perspectives
Authors: Bardanzellu Flaminia , Fanos Vassilios , Reali Alessandra
Published: November 2018

Breast Milk (BM) is the best source of nutrition for newborns, especially if premature. In fact, its beneficial impact on short- and the long-term neonatal outcome has was deeply described.

Unfortunately, BM could not be always so safe, especially due to the possible presence of maternal viruses that can be shed and transferred to the breastfed neonate. Among these, Cytomegalovirus (CMV) can potentially lead to a serious and acute illness, mostly in case of low gestational age.

Some studies also report the association of CMV-acquired infection to an increased risk of structural and functional brain modifications and neurological impairment.

Due to these reasons, a strategy to remove CMV from BM with a minimal or absent impact on its beneficial components would be desirable.

Up to now, pasteurization, freezing, ultraviolet- C or microwave irradiation are the available techniques; they show different levels of efficacy and variable effects on BM composition, even if many studies are still needed to fully clarify these implications.

In this review, we provide an update of the current evidence about these topics. We focus on the factors promoting CMV shedding through BM; moreover, the possible occurrence of a severe disease in preterm neonates is also described. Finally, we investigate the potential effects showed on BM properties by the strategies that prevent or reduce viral transmission, therefore influencing newborns’ health, and the new techniques which could show a relevant role in the next future, such as metabolomics.
Arterial Hypertension and Multiple Myeloma: Physiopathology and Cardiovascular Risk and ‘Practical’ Indications in Patients Receiving Carfilzomib
Authors: Milan Alberto , Bruno Giulia , Maffei Ilaria , Iannaccone Andrea , Ravera Agnese , Schiavone Domenica , Veglio Franco
Published: November 2018

The introduction of carfilzomib in the treatment of relapsing and refractory multiple
myeloma has allowed a significant increase in survival. The most frequent adverse effect of Carfilzomib
treatment is arterial hypertension, even though the exact physiopathological mechanism are
still unclear. MM patients, on the other hand, often present significant cardiovascular risk factors
and comorbidities. Uncontrolled hypertension is frequently the cause of cardiovascular complications.
It has been estimated that up to 50% of subjects in the general population are unaware of their
hypertensive condition and only half of those who are aware of this risk factor present good control
of blood pressure. Although the management of arterial hypertension is clearly important in reducing
the risk of cardiovascular events, and is well described by the current guidelines, no clear indications
are provided on how to approach and treat specifically MM patients undergoing treatment
with proteasome inhibitors. The aim of our work is to summarize a practical approach to the stratification
of cardiovascular risk of hypertensive in patients who are candidates for or actively treated
with carfilzomib for refractory multiple myeloma (MMR). MM patients eligible for carfilzomib
treatment should preliminary undergo a careful cardiovascular risk stratification. Perspective studies
will help to better identify the specific risk factors that should be considered and treated in these
patients.
An Extensive Simulation Study of Gate Underlap Influence on Device Performance of Surrounding Gate In0.53Ga0.47As/InP Hetero Field Effect Transistor
Authors: Mohanty Soumya S. , Bhanja Urmila , Mishra Guru P.
Published: November 2018

Background:

This work describes the implementation of In0.53Ga0.47As/InP Surrounding
Metal Gate Oxide Semiconductor Heterostructure Field Effect Transistor (SG MOSHFET)
with gate underlap on both source and drain end to improve the DC and RF performance.

Methods:

A comprehensive and methodological investigation of DC and RF performance of III-V
semiconductor are made for different underlap length varying from 5nm to 30nm on both sides of
the device, which is used to mitigate the short channel issues to improve the device performance.
Hydrodynamic model has been taken into consideration for the device simulation and it also includes
Auger recombination and the Shockley–Read–Hall (SRH) model. Simulation is performed
to analyze the various analog performance of device like drain current, surface potential, transconductance,
threshold voltage, drain induced barrier lowering, off current, subthreshold slope,
Ion/Ioff ratio, output conductance, intrinsic delay, energy-delay product, transconductance generation
factor and radio frequency performance of device, like trans-frequency product and cut-off
frequency.

Results:

From the simulation, it can be observed that an improved analog and RF performance is
obtained at the optimum underlap length.

Conclusion:

This work delivers an idea for extended researchers to investigate different aspects of
group III–V underlap MOSFETs.
Ketogenic Diet Acts on Body Remodeling and MicroRNAs Expression Profile
Authors: Cannataro Roberto , Perri Mariarita , Gallelli Luca , Caroleo Maria Cristina , De Sarro Giovambattista , Cione Erika
Published: November 2018

Background:

The Ketogenic Diet (KD) promotes metabolic changes and optimizes energy metabolism. It is unknown if microRNAs (miRs) are influenced by KD in obese subjects. The screening of circulating miRs was performed with the FDA approved platform n-counter flex and blood biochemical parameters were dosed by ADVIA 1800.  Objectives: The aim of this study was to evaluate mir profile under 6 weeks of biphasic KD in obese subjects. We enrolled 36 obese subjects (18 females and 18 males) in stage 1 of Edmonton Obesity Staging System (EOSS) parameter.  Result: Any correlation was found between biochemical parameter and three miRs, hsa-let-7b-5p, hsa-miR-143-3p and hsa-miR-504-5p influenced in an equal manner in both sexes. The KD resulted safe and ameliorate both biochemical and anthropometric factors in obese subjects re-collocating them into stage 0 of EOSS parameters.

Conclusion:

The miRs herein identified under KD might be a useful tool to monitor low carbohydrate nutritional regimens which reflect indirectly the regulatory biochemical mechanisms and cell signaling that orchestrate metabolic and signaling pathways.
Háztartási méretű kiserőművek villamosenergia-ellátásban betöltött szerepe a magyarországi településállományban
Authors: Kulcsár Balázs
Published: November 2018

A megújuló energiaforrások viharos gyorsaságú és világméretű terjedése során egyre több település tűzi ki célul, energiaigényének kielégítését megújuló forrásokból. Magyarország energiamérlegében ma még jelentős részt tesznek ki a fosszilis energiahordozók, amelyek többsége importtal biztosított. Az energiafüggőség csökkentése, az energiabiztonság növelése, a környezeti szempontok figyelembe vétele és a települések energiaköltségének csökkentése érdekében elkerülhetetlen a megújuló energiaforrásokból származó energia részarányának növelése. Magyarország érdeke is az, hogy a megújuló energiaforrások részarányát növelje az energiaellátásban. Ennek érdekében, a 2007-es Villamos energia törvény (VET) (2007. évi LXXXVI. törvény, a villamos energiáról) létrehozta az 50 kVA teljesítménynél kisebb összes teljesítményű háztartási méretű kiserőmű (HMKE) kategóriát. Ebben a kategóriában megújuló és fosszilis forrásból is előállítható villamos energia. A 2015 végéig installált kapacitás 99,6%-a megújuló forrásból származik, 99%-a pedig napenergiából. A HMKE kategória bevezetése óta eltelt hét évben, annak beépített országos összes kapacitása ugrásszerűen növekedett. Az összes teljesítőképesség 2008. év végén még 0,51 MW volt, míg 2015. év végére már megközelítette a 129 MW-ot. Az összes teljesítőképesség 2008-tól 2015-ig minden évben az előző évi többszörösére emelkedett és további dinamikus kapacitásbővülés várható. A kapacitások és az általuk termelt villamos energia települési szintű adatként is megjeleníthető. A vizsgálatok célja, annak megállapítása, hogy pusztán e legkisebb erőmű kategóriában kiépült kapacitás milyen arányban képes részt venni az egyes magyarországi települések villamosenergia-ellátásában. Azaz, az így termelt villamos energia mekkora százalékát elégíti ki a helyi villamosenergia-igényeknek. Ez alapján felállítható egy települési rangsor, amely megmutatja az önellátás mértékét a megújuló energiaforrásból származó villamosenergia-előállítás terén, továbbá lehetőséget ad az energiaváltás megvalósításának tervezésére. Végezetül a célértékek elérése tekintetében milyen mértékben lehet alapozni e legkisebb erőmű kategóriára.
Estructura, composición y diversidad arbórea y arbustiva en tres condiciones de manejo forestal de Ixtlán de Juárez, Oaxaca.
Authors: Vásquez-Cortez Vicente Florencio , Clark-Tapia Ricardo , Manzano-Méndez Filemón , González-Adame Gabriel , Aguirre-Hidalgo Victor
Published: November 2018

Las prácticas forestales implican una serie de actividades que pueden generar impactos negativos en la dinámica natural de este ecosistema. El objetivo de este estudio fue evaluar el efecto del manejo forestal en la estructura, composición y diversidad arbórea y arbustiva en Ixtlán de Juárez, Oaxaca. Para ello se establecieron 15 unidades de muestreo distribuidas en tres condiciones de manejo: franjas no aprovechadas (FNA), bordes (B) y franjas aprovechadas (FA) establecidos en bosques con tratamiento de matarrasa. Se describen los cambios en estructura, composicón florística y diversidad de los estratos de árboles y arbustos. Durante el periodo de estudio se identificaron 27 especies vegetales distribuidas en nueve familias. Las especies más frecuentes fueron: Quercus crassifolia Humb & Bonpl., Pinus pseudostrobus Lindl. y Quercus laurina Humb. & Bonpl. Las curvas de acumulación de especies mostraron que las FNA tuvieron un mayor número de especies que las otras dos áreas. La estructura, estimada a partir de los índices de valor de importancia (IVI) y de valor forestal (IVF), estuvo asociada a la presencia de las tres especies previamente mencionadas en las tres condiciones. La categoría fustal fue la dominante en FNA y B; mientras que en FA las categorías dominantes fueron las de latizal y brinzal. Los valores de riqueza fueron bajos en FNA, B, FA, pero con valores altos de equidad. El valor de dominancia fue solamente alto en FA; B y FA fueron los más semejantes entre sí. Se concluye que las prácticas silviculturales promueven la conformación de un bosque coetáneo con dominancia de pinos. Este patrón es menos severo dada la presencia de las FNA, las cuales podrían limitar la pérdida de la diversidad arbórea y arbustiva.
Preferences of Information Dissemination on Treatment for Bipolar Disorder: Patient-Centered Focus Group Study (Preprint)
Authors: Kerner Berit , Crisanti Annette S , DeShaw Jason L , Ho Janika-Marie G , Jordan Kimmie , Krall Ronald L , Kuntz Matt J , Mazurie Aurélien J , Nestsiarovich Anastasiya , Perkins Douglas J , Schroeter Quentin L , Smith Alicia N , Tohen Mauricio , Volesky Emma , Zhu Yiliang , Lambert Christophe G
Published: November 2018

BACKGROUND

Patient education has taken center stage in successfully shared decision making between patients and health care providers. However, little is known about how patients with bipolar disorder typically obtain information on their illness and the treatment options available to them.

OBJECTIVE

This study aimed to obtain the perspectives of patients with bipolar disorder and their family members on the preferred and most effectively used information channels on bipolar disorder and the available treatment options.

METHODS

We conducted nine focus groups in Montana, New Mexico, and California, in which we surveyed 84 individuals including patients with bipolar disorder and family members of patients with bipolar disorder. The participants were recruited using National Alliance on Mental Illness mailing lists and websites. Written verbatim responses to semistructured questionnaires were analyzed using summative content analysis based on grounded theory. Two annotators coded and analyzed the data on the sentence or phrase level to create themes. Relationships between demographics and information channel were also examined using the Chi-square and Fisher exact tests.

RESULTS

The focus group participants mentioned a broad range of information channels that were successfully used in the past and could be recommended for future information dissemination. The majority of participants used providers (74%) and internet-based resources (75%) as their main information sources. There was no association between internet use and basic demographics such as age or geographical region of the focus groups. Patients considered time constraints and the fast pace in which an overwhelming amount of information is often presented by the provider as major barriers to successful provider-patient interactions. If Web-based channels were used, the participants perceived information obtained through Web-based channels as more helpful than information received in the provider’s office (P<.05).

CONCLUSIONS

Web-based resources are increasingly used by patients with bipolar disorder and their family members to educate themselves about the disease and its treatment. Although provider-patient interactions are frequently perceived to be burdened with time constraints, Web-based information sources are considered reliable and helpful. Future research should explore how high-quality websites could be used to empower patients and improve provider-patient interactions with the goal of enhancing shared decision making between patients and providers.
Sentido y desarrollo de la Licenciatura en Ciencias Políticas y Políticas y Administración Pública.
Authors: Uvalle Berrones Ricardo
Published: November 2018

El autor expone la dimensión institucional de la licenciatura en Ciencias Políticas y Administración Pública, destacando su perfil multidisciplinario, así como sus compromisos y aportaciones. Señala que la labor del Estado es fundamental para el desarrollo de la vida democrática de las sociedades, y que ello plantea retos específicos para los egresados de la carrera.
La violencia de género en México: reto del gobierno y de la sociedad.
Authors: Díaz Pérez Guillermina
Published: November 2018

La autora aborda el tema de la violencia hacia la mujer desde la perspectiva de género, destacando su significado, tipos así como su contexto histórico. Argumenta sobre los principios de la equidad de género y hace una revisión sobre los programas y políticas que han tratado de enfrentar el problema en México, lo cual sustenta con una selección de datos estadísticos.
La dinámica contemporánea en los procesos de gestión pública gubernamental.
Authors: Ballesteros Mesa Sergio Víctor
Published: November 2018

El autor aborda desde una perspectiva organizacional el perfil procedimental contemporáneo de la Administración Pública. Para ello, expone un modelo que se articula por fases en el que se parte de la definición general de los objetivos institucionales hasta la materialización de las actividades específicas en las instancias administrativas. Asimismo, reflexiona sobre el impacto de la gestión por procesos en el caso de México.
Bienes públicos: una aproximación al debate.
Authors: González Valadez Isaí
Published: November 2018

El autor analiza el concepto de bien y lo sitúa en el debate de la redefinición de lo público y lo privado. Examina las implicaciones que dicha categoría tiene en términos de las responsabilidades del Estado como generador de beneficios colectivos, en un contexto donde la iniciativa ciudadana y el mercado reclaman para sí esferas que requieren de una regulación clara en cuanto a competencias, responsabilidades y atribuciones
Aportes del desarrollo organizacional a la Administración Pública Municipal.
Authors: Cruz Meléndez Christian Arturo
Published: November 2018

El Desarrollo Organizacional es una herramienta de la administración cuyo objetivo principal es propiciar el cambio planeado a fin de mejorar el desempeño en aspectos administrativos, organizacionales, tecnológicos, sociales y culturales. Surge del sector privado y es ahí donde se ha aplicado regularmente, sin embargo, en este trabajo el autor propone que se utilice en la Administración Pública Municipal, tomando en cuenta ciertas consideraciones teóricas.