bluuebunny/crossref_metadata_2025 huggingface dataset:
Revealing Chaos Synchronization Below the Threshold in Coupled Mackey–Glass Systems
Authors: Akhmet Marat , Başkan Kağan , Yeşil Cihan
Published: July 2023

This study presents a novel concept in chaos synchronization, delta synchronization of chaos, which reveals the presence of chaotic models evolving in unison even in the absence of generalized synchronization. Building upon an analysis of unpredictability in Poincaré chaos, we apply this approach to unilaterally coupled time-delay Mackey–Glass models. The main novelty of our investigation lies in unveiling the synchronization phenomenon for a coupling constant below the synchronization threshold, an unattainable domain for conservative methods. Furthermore, we rigorously examine the coexistence of generalized synchronization and complete synchronization of unpredictability, which is a special case of delta synchronization, above the threshold. Therefore, the threshold is no longer a requirement for the synchronization of chaos in view of the present results. Additionally, transitions to fully chaotic regimes are demonstrated via return maps, phase portraits, and a bifurcation diagram. The findings are substantiated by tables and novel numerical characteristics.
Cytokine Responses during Mycobacterium tuberculosis H37Rv and Ascaris lumbricoides Costimulation Using Human THP-1 and Jurkat Cells, and a Pilot Human Tuberculosis and Helminth Coinfection Study
Authors: Bhengu Khethiwe N. , Singh Ravesh , Naidoo Pragalathan , Mpaka-Mbatha Miranda N. , Nembe-Mafa Nomzamo , Mkhize-Kwitshana Zilungile L.
Published: July 2023

Background: Helminth infections are widespread in tuberculosis-endemic areas and are associated with an increased risk of active tuberculosis. In contrast to the pro-inflammatory Th1 responses elicited by Mycobacterium tuberculosis (Mtb) infection, helminth infections induce anti-inflammatory Th2/Treg responses. A robust Th2 response has been linked to reduced tuberculosis protection. Several studies show the effect of helminth infection on BCG vaccination and TB, but the mechanisms remain unclear. Aim: To determine the cytokine response profiles during tuberculosis and intestinal helminth coinfection. Methods: For the in vitro study, lymphocytic Jurkat and monocytic THP-1 cell lines were stimulated with Mtb H37Rv and Ascaris lumbricoides (A. lumbricoides) excretory-secretory protein extracts for 24 and 48 h. The pilot human ex vivo study consisted of participants infected with Mtb, helminths, or coinfected with both Mtb and helminths. Thereafter, the gene transcription levels of IFN-γ, TNF-α, granzyme B, perforin, IL-2, IL-17, NFATC2, Eomesodermin, IL-4, IL-5, IL-10, TGF-β and FoxP3 in the unstimulated/uninfected controls, singly stimulated/infected and costimulated/coinfected groups were determined using RT-qPCR. Results: TB-stimulated Jurkat cells had significantly higher levels of IFN-γ, TNF-α, granzyme B, and perforin compared to unstimulated controls, LPS- and A. lumbricoides-stimulated cells, and A. lumbricoides plus TB-costimulated cells (p < 0.0001). IL-2, IL-17, Eomes, and NFATC2 levels were also higher in TB-stimulated Jurkat cells (p < 0.0001). Jurkat and THP-1 cells singly stimulated with TB had lower IL-5 and IL-4 levels compared to those singly stimulated with A. lumbricoides and those costimulated with TB plus A. lumbricoides (p < 0.0001). A. lumbricoides-singly stimulated cells had higher IL-4 levels compared to TB plus A. lumbricoides-costimulated Jurkat and THP-1 cells (p < 0.0001). TGF-β levels were also lower in TB-singly stimulated cells compared to TB plus A. lumbricoides-costimulated cells (p < 0.0001). IL-10 levels were lower in TB-stimulated Jurkat and THP-1 cells compared to TB plus A. lumbricoides-costimulated cells (p < 0.0001). Similar results were noted for the human ex vivo study, albeit with a smaller sample size. Conclusions: Data suggest that helminths induce a predominant Th2/Treg response which may downregulate critical Th1 responses that are crucial for tuberculosis protection.
All-Fiber Narrow-Bandwidth Mode-Locked Laser Based on Polarization-Dependent Helical Long-Period Grating
Authors: Wan Ying , Jiang Chen , Zhang Zuxing , Mao Yaya , Ren Jianxin , Wen Jianxiang , Liu Yunqi
Published: July 2023

As a crucial component of nonlinear polarization rotation (NPR) mode locking, optical fiber gratings offer advantages such as polarization modulation capability, stability, fiber compatibility, and preparation maturity, making them a vital technological foundation for achieving NPR mode locking. Here, a polarization-maintaining fiber helical long-period grating (PMF-HLPG) was designed and fabricated as a polarizer using the CO2-laser direct-write technique to realize the NPR effect. A homemade fiber Bragg grating (FBG) was also introduced into the laser system to enable a narrow-bandwidth lasing output and wavelength tunability. Based on the PMF-HLPG and FBG mentioned above, an all-fiber mode-locked laser with a spectra bandwidth of 0.15 nm was constructed to generate stable short pulses with a fundamental repetition rate of 12.7122 MHz and a pulse duration of 30.08 ps. In particular, its signal-to-noise ratio is up to 84.5 dB, showing the high stability of the laser. Further, the operating wavelength of the laser can be tuned from 1559.65 nm to 1560.29 nm via heating the FBG while maintaining its mode-locked state with stability. The results indicate that the PMF-HLPG could be used as a polarizer to meet the NPR mechanism for ultrashort pulse laser applications in optical communication, optical sensing, and biomedical imaging.
The Antioxidant Activity of Mistletoes (Viscum album and Other Species)
Authors: Nicoletti Marcello
Published: July 2023

In addition to the European mistletoe, Viscum album, which is the most known and utilized one, there are several species commonly known as mistletoe. They are spread in various regions of the planet and are all characterized by hemiparasitism and epiphytic behaviour. The published studies evidence other similarities, including the sharing of important biological properties, with the common presence of antioxidant effects. However, whereas the European mistletoe is largely utilized in medical treatments, although with controversial aspects, the scientific knowledge and medical uses of other mistletoes are still insufficient. This review focuses on the controversial medical story of European mistletoe regarding its antioxidant activity and the potentiality of the other species named mistletoe pertaining to botanical families and genera different from Viscum.
Comparison of Conventional and Green Extraction Techniques for the Isolation of Phenolic Antioxidants from Sea Fennel
Authors: Veršić Bratinčević Maja , Kovačić Rea , Popović Marijana , Radman Sanja , Generalić Mekinić Ivana
Published: July 2023

In this study, different extraction methods were compared for the isolation of bioactive phenolic compounds from sea fennel: microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), and conventional solvent extraction (CSE). Total phenolics, flavonoids, and tannins were determined spectrophotometrically. In contrast, the determination of individual phenolics was performed by high-performance liquid chromatography coupled with an ultraviolet/visible detector (HPLC-UV/VIS). Two in vitro assays (ferric reducing antioxidant power (FRAP) and 2,2-diphenyl-1-picryl-hydrazyl (DPPH)) were performed to determine antioxidant activity. The maximum extraction of phenolic compounds was achieved with 50% ethanol, while the MAE method showed the highest extraction efficiency, with a total phenolic content of more than 25 mg of gallic acid equivalents (GAE)/mg and a chlorogenic acid content of more than 10 mg/g, respectively. The highest antioxidant potential was also observed in the samples from MAE (the FRAP value ranged from 173 to 185 µmol Fe2+/g, and the DPPH inhibition ranged from 55 to 59%), which was consistent with the extraction results. Although the phenolic antioxidants of sea fennel have been extensively studied recently, to the authors’ knowledge, this study was the first to evaluate the application of the new techniques for their isolation and to show the advantages of MAE compared to the other techniques used.
Impacts of Inlet Circumferential Distortions on the Aerodynamic Performance of a Transonic Axial Compressor
Authors: Yang Bo , Zhu Guoming
Published: July 2023

Distortion, such as total pressure distortion, is a common phenomenon at the inlet of an axial compressor. Nonuniform inflow can greatly affect the aerodynamic performance and the stability of the compressor. In this paper, a sinusoidal distortion model is used at the inlet. Then, a series of unsteady computational fluid dynamics (CFD) simulations with a full-annulus model is conducted. Three kinds of the total pressure distortions, such as circumferentially covering 60, 120, and 180-degs sectors above 70% span of the blade at the inlet section, are adopted. Based on the results, how the rotating stall cells can be induced and developed under the different inlet conditions is understood during the stall process. It is found that the secondary stall cell is more easily triggered when the circumferential range of total pressure distortion is increased. Meanwhile, the influence of the rotating distortion on the compressor performance is also studied and a dangerous distortion rotating speed is observed.
The Migration Mechanism of BTEX in Single- and Double-Lithology Soil Columns under Groundwater Table Fluctuation
Authors: Zheng Jingwei , Yang Yang , Li Juan , Zhang Hao , Ma Yan
Published: July 2023

The migration of light non-aqueous phase liquids (LNAPLs) trapped in porous media is a complex phenomenon. Groundwater table fluctuation can not only affect contaminant migration but also redox conditions, bacterial communities, and contaminant degradation. Understanding LNAPLs’ (e.g., benzene, toluene, ethylbenzene, and xylene (BTEX)) behavior within porous media is critical for the high efficiency of most in situ remediation systems. A laboratory study of single- and double-lithology soil column investigation of the groundwater table fluctuation effect on BTEX transport, using benzene and toluene as typical compounds, in a typical representative model of aquifers subjected to water table fluctuation was undertaken in this study. The results show that benzene and toluene migration in single-lithology soil columns packed with sand was mainly affected by flushing due to the hydraulic force induced by water table fluctuations and that the double-lithology soil column packed with sand and silt was significantly affected by retention due to the higher adsorption induced by 10 cm of silt. The dissolution mainly correlated with the BTEX migration in saturated zones, and the contaminant concentration increased when the water table fell and decreased when the water table rose. For a contaminated site with a single-lithology structure consisting of sand, more attention should be paid to organic contaminant removal within the groundwater, and a double-lithology structure containing silt is more suited to the removal of organic contaminants from the silt layer. The difference in biodegradation kinetics between the groundwater table fluctuation (GTF) zone and the saturated zone should be better understood for the remediation of BTEX compounds.
Lyme Disease General Practice Sentinel Scheme
Authors: Douglas James , Holden Samantha , Hines Frances , Eze Jude , Bradley Clare , Finlayson James , Vyse Andrew , Loew-Baselli Alexandra , Mavin Sally
Published: July 2023

Background

Lyme Disease (LD) is a multisystem zoonosis with uncertain epidemiology. It may be increasing in rural hotspots. GP datasets are weakened by coding and definitions. Public and climate concerns have raised awareness of LD.

Aim

Improving diagnostic coding, UK Lyme Disease incidence and distribution. Behavioural risk factors for public health policy.

Method

Education modules for 35 general practices from Orkney to Southampton.

Remote installation of software providing decision support, case definitions, pictures, coding, prescribing guidelines. Questionnaire on tick exposure and removal methods. Anonymous data extraction.

Data on tick bite body location, age, place of exposure, attachment time, removal methods, leisure pursuits and occupation to guide public health policy.

GP data capture and coding from hospital, A&E and OOH (out of hours) records.

Erythema Migrans (EM) is a clinical diagnosis without serological testing. Rash photographs establish a data bank of disease expression in age groups, ethnicity, and skin types.

Results

There were 69 cases reported in the pilot period (September to December 2021), 52% diagnosed EM following a definite tick bite. Tick attachment time showed a majority > 24 hours, with home tweezers, fingernails often used for removal, with both associated with higher disease transmission.

Analysis of pilot data suggested a Lyme Disease incidence of 94/100 000 with the inclusion of EM. This compares to a serologically confirmed incidence of 38.2/100 000 in 2019 in Highland Region.

Conclusion

Early data suggests that the Lyme Disease General Practice Sentinel Scheme has improved case ascertainment, epidemiology, and risk factor understanding.
Service-learning and community engagement in medical school: do we need to change the way we think about student placements?
Authors: Vaidyanathan Anjali , Khoursheed Layal , Merrifield Sarah
Published: July 2023

Background

Service-learning is a form of experiential education that is beginning to be implemented internationally within undergraduate curriculums. It has the potential to significantly enhance clinical practice and students’ learning, while simultaneously addressing community needs. Embedding civic engagement into students’ learning should aim to increase understanding of populations as well as enhance clinical prowess.

Aim

The aim of this research is to explore the benefit of service-learning for medical students and consider ways in which it can be further incorporated into curriculums.

Method

This systematic review looked at research through PubMed, OVID, Taylor & Francis online journals, and Manchester University’s library sources. The research considered publications dealing with different types of service-learning for medical students.

Results

In total, 14 key papers were identified. The results demonstrated that service-learning is a way of actively learning, providing a service to the community, and enabling students to learn from people of wider professions. The use of student-led clinics enabled students to develop their interpersonal skills while serving society. There was also evidence that service-learning enhanced skill development, such as empathy, team working, and communication skills.

Conclusion

Student placements are often thought of in a clinical setting where students shadow doctors in a less active role. The research shows that over the past 20 years, incorporation of service-learning into medical programmes has been more commonplace and is an effective addition to the curriculum. It combines clear learning objectives with service provision to communities, in order to aid in medical students’ education and the development of necessary clinical skills.
Rancang Bangun Alat Monitoring dan Pembatas Konsumsi Energi Listrik
Authors: Prasetia Vicky
Published: July 2023

Alat pemantau energi adalah alat yang digunakan untuk memantau arus, tegangan dan daya listrik. Sebagian besar orang belum mengenal teknologi ini dan saat ini tidak ada fitur untuk membatasi penggunaan energi listrik. Pembuatan alat pemantau energi bertujuan untuk mengatasi masalah penggunaan energi yang berlebihan dengan menciptakan perangkat pemantauan serta pengatur batas konsumsi energi listrik. Perangkat ini mampu memantau penggunaan arus, voltase, daya, dan  energi, dan pengguna  dapat mengatur konsumsi energinya melalui aplikasi seluler. Alat ini menggunakan modul bluetooth yang dapat dikontrol dengan mudah oleh pengguna. Beberapa komponen utama untuk membuat alat ini adalah Arduino Mega 2560, PZEM-004T. Pada hasil pengujian alat pemantau energi diperoleh pembacaan multimeter dan pengukuran PZEM dengan tegangan rata-rata  0,88 V, dengan selisih rata-rata 0,31 A pada pengukuran arus.
MENINGKATKAN KEMAMPUAN KOGNITIF ANAK USIA DINI MELALUI AKTIVITAS MENGGAMBAR DAN MEWARNAI
Authors: Masganti Sitorus  , Rahma Adlya Zahra  , Rama Yuspika Sari  , Sarah Rizky Aulia  , Salsabila Siregar
Published: July 2023

This study aims to investigate the effect of drawing and coloring activities on improving early childhood cognitive abilities. Drawing and coloring activities are considered as fun and creative activities for children, but they also have the potential to improve their cognitive abilities. The research method used was an experiment with a control group. Fifty children aged 4-6 years were randomly selected and divided into two groups, namely the experimental group which did drawing and coloring activities, and the control group which did not. The experimental group was given a series of drawing and coloring tasks designed to engage various cognitive aspects such as color recognition, hand-eye coordination, problem solving, and spatial understanding. Meanwhile, the control group was involved in daily routine activities without any special intervention. Before and after the intervention, both groups were given cognitive ability tests which included tests of memory, problem solving, and understanding of basic concepts. The results showed that the group of children who did drawing and coloring activities experienced a significant increase in cognitive abilities compared to the control group. They showed better improvements in memory tests, problem solving, and understanding basic concepts. In addition, children in the experimental group also showed an increase in their creativity and imagination. These findings indicate that drawing and coloring activities can be an effective method of improving early childhood cognitive abilities. Therefore, it is suggested that these activities be integrated in the early childhood education curriculum to enrich their learning experience and promote optimal cognitive development.
Pengaruh Efikasi Diri Dan Keseja Pengaruh Efikasi Diri Dan Kesejahteraan Spiritual Terhadap Stres Kerja Pada Guru TK
Authors: Valentina Fetasya Ayu , Maharani Ega Asnatasia
Published: July 2023

Guru TK merupakan pekerjaan yang memicu stres kerja tinggi. Stres kerja yang timbul dapat memunculkan gejala negatif yang mengganggu proses jalannya pembelajaran. Efikasi diri dan kesejahteraan spiritual sebagai faktor individual dapat membantu guru TK mengatasi kondisi stres kerja yang dialami. Penelitian ini bertujuan untuk melihat pengaruh efikasi diri dan kesejahteraan spiritual secara parsial maupun simultan, serta mengetahui variabel yang menjadi prediktor terkuat terhadap stres kerja pada guru TK. Jenis penelitian adalah korelasional. Teknik pengambilan sampel menggunakan metode Simple Random Sampling dengan jumlah sampel sebesar 174 guru TK di Kabupaten Bantul. Proses pengumpulan data melalui kuesioner penelitian yang disebar secara online dan offline. Teknik analisis data yaitu analisis regresi linier berganda. Hasil penelitian menunjukkan secara parsial efikasi diri tidak berpengaruh negatif terhadap stres kerja sedangkan kesejahteraan spiritual berpengaruh negatif terhadap stres kerja pada guru TK. Dapat diartikan jika kesejahteraan spiritual meningkat maka stres kerja akan menurun, begitu juga sebaliknya. Secara simultan efikasi diri dan kesejahteraan spiritual berpengaruh terhadap stres kerja sebesar 18.3%. dengan kesejahteraan spiritual sebagai prediktor terkuat terhadap stres kerja dibandingkan efikasi diri.
DEVELOPMENT OF BOSUR BEACH TOURISM DESTINATION IN TAPANULI TENGAH REGENCY
Authors: Pratama Nasution Fuad , Ginting Nurlisa , Delianur Nasution Achmad
Published: July 2023

Central Tapanuli Regency has the longest coastline on the western coast of Sumatra Island, approximately 200 km, and it is adorned with beautiful beaches and scattered small islands in the Indian Ocean. One of the many stunning beaches with great tourism potential in Central Tapanuli Regency is Bosur Beach. The Bosur Beach area is a white sandy beach located in the Pandan District, which holds immense tourism potential and opportunities for development as a nationally renowned tourist destination. The purpose of this research is to identify the obstacles faced by Bosur Beach as a tourist destination and formulate strategies for its development. Obstacles in the aspect of tourist attractions include inadequate management, lack of attention to waste management, poorly planned and designed huts or relaxation areas, burning of trash in corners of the beach area by the management, absence of local traditions and rituals at Bosur Beach, limited variety of handcrafted products available for trade, and the current absence of beach signboards due to previous vandalism by irresponsible visitors. Furthermore, no unique features are found in the artificial attractions at the beautiful Pandan Beach tourist destination. Obstacles identified in the amenities aspect include the absence of trash bins, parking areas that do not meet standard requirements, dilapidated and outdated toilet floors and buildings, aesthetically unpleasing seating designs lacking functional shade, the absence of designated areas for ablution (wudhu) for visitors who wish to pray, and the deteriorated ceiling and faded paint of the mosque building. There are vacant shops in the beach area; however, the vendors use tricycles (becak) for flexibility, and the rental costs are relatively lower as electricity is not required for the kiosks' lighting. Obstacles found in the accessibility aspect include the limited use of regular public transportation by tourists, the road only consisting of two lanes with a width of approximately 4 meters, which is insufficient for accommodating two buses passing each other simultaneously, the absence of bus stops and traffic signs indicating the direction to Bosur Beach. Obstacles in the aspect of the image include the accumulation and burning of trash at various points on Bosur Beach and the lack of distinctiveness that sets Bosur Beach apart from other beaches in Indonesia, making it similar to the common beaches found throughout the country. Obstacles in the price aspect include higher motorized tricycle fares due to the absence of standardized prices, leading to a mismatch between visitor expectations and the quality of facilities provided within Bosur Beach, such as toilet, prayer rooms
Prospectiva y Vigilancia Tecnológica como Estrategias Innovadoras de la Universidad para Promover la Transferencia de Conocimientos
Authors: Gloria Paredes María , Guillermo Maldonado Luis
Published: July 2023

En la sociedad actual se está requiriendo de nuevos e innovadores enfoques para atender las crisis y desafíos sociales, ambientales y económicos. La innovación clave del proceso innovativo se desarrolla en un marco general sistémico y de múltiples actores que constituye el Sistema Nacional de Ciencia, Tecnología e Innovación (SNCTI), donde la Universidad juega un rol preponderante en la gestión y transferencia de conocimientos. En este contexto, el estudio plantea la pregunta: ¿Cuáles son las principales contribuciones del uso de la Prospectiva y Vigilancia Tecnológica como estrategias innovadoras desde la Universidad para promover la Transferencia de Conocimientos? Para responder propone: (1) contextualizar los desafíos de la Universidad en los que los conceptos de prospectiva y vigilancia tecnológica son definidos, así como sus estrategias y alcance; (2) determinar los mecanismos del proceso de transferencia de conocimiento y tecnología en la Universidad, así como las posibilidades y contribuciones de la prospectiva y VT como herramientas innovadoras y (3) presentar las experiencias detectadas de la aplicación de la Prospectiva y VT como estrategias innovadoras en universidades para promover la transferencia de conocimientos. Metodológicamente, el trabajo se basa en la colección, análisis y evaluación de datos e informaciones de fuentes secundarias. Primeramente, se realizó una revisión de literatura de textos y estudios sobre la prospectiva y VT y luego se colectaron los datos contenidos en publicaciones, informes, documentos y reportes disponibles de las Universidades. Posteriormente, los datos colectados se utilizaron para presentar las experiencias de aplicación por Universidades. Finalmente, se concluye que, al adoptar estas estrategias, las Universidades pueden anticipar los cambios futuros, adaptarse a las demandas del mercado laboral y tecnológico, así como promover la colaboración con los sectores involucrados.
What Do Halo CMEs Tell Us about Solar Cycle 25?
Authors: Gopalswamy Nat , Michalek Grzegorz , Yashiro Seiji , Mäkelä Pertti , Akiyama Sachiko , Xie Hong
Published: July 2023

It is known that the weak state of the heliosphere due to diminished solar activity in cycle 24 backreacted on coronal mass ejections (CMEs) to make them appear wider for a given speed. One of the consequences of the weak state of the heliosphere is that more CMEs appear as halo CMEs (HCMEs), and halos are formed at shorter heliocentric distances. Current predictions for the strength of solar cycle (SC) 25 range from half to twice the strength of SC 24. We compare the HCME occurrence rate and other properties during the rise phase of cycles 23, 24, and 25 to weigh in on the strength of SC 25. We find that HCME and solar wind properties in SC 25 are intermediate between SCs 23 and 24, but closer to SC 24. The HCME occurrence rate, normalized to the sunspot number, is higher in SCs 24 and 25 than in SC 23. The solar wind total pressure in SC 25 is ∼35% smaller than that in SC 23. Furthermore, the occurrence rates of high-energy solar energetic particle events and intense geomagnetic storms are well below the corresponding values in SC 23, but similar to those in SC 24. We conclude that cycle 25 is likely to be similar to or slightly stronger than cycle 24, in agreement with polar-field precursor methods for cycle 25 prediction.
TP53-MUTATED MYELODYSPLASIA AND ACUTE MYELOID LEUKEMIA
Authors: Testa Ugo , Castelli Germana , Pelosi Elvira
Published: July 2023

TP53-mutated myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) form a distinct and heterogeneous group of myeloid malignancies associated with poor outcomes. Studies carried out in the last years have in part elucidated the complex role played by TP53 mutations in the pathogenesis of these myeloid disorders and in the mechanisms of drug resistance. A consistent number of studies has shown that some molecular parameters, such as the presence of a single or multiple TP53 mutations, the presence of concomitant TP53 deletions, the association with co-occurring mutations, the clonal size of TP53 mutations, the involvement of a single (monoallelic) or of both TP53 alleles (biallelic) and the cytogenetic architecture of concomitant chromosome abnormalities are major determinants of outcomes of patients. The limited response of these patients to standard treatments, including induction chemotherapy, hypomethylating agents, and venetoclax-based therapies and the discovery of an immune dysregulation have induced a shift to new emerging therapies, some of which being associated with promising efficacy. The main aim of these novel immune and nonimmune strategies consists in improving survival and in increasing the number of TP53-mutated MDS/AML patients in remission amenable to allogeneic stem cell transplantation.

Keywords: myelodysplastic syndromes; acute myeloid leukemias; TP53; molecular abnormalities; gene sequencing; cytogenetic characterization
Assessing Early Childhood Development Teachers’ Perceptions on the Use of the Flipped Classroom Method in the Teaching and Learning Process in Zimbabwe.
Authors: Nkomo Dr. Sikhangezile , Makonye Dr Leah
Published: July 2023

Globally, the (COVID-19) epidemic brought about a crisis in schooling that had never been seen before. Due to this situation, all face-to-face interactions within educational institutions had to be suspended in order to stop the virus’s transmission and lessen its effects. Traditional pedagogical techniques of instruction were automatically suspended as a result of the ongoing lockdown limitations. The adaptation of new online teaching and learning methodologies. One method of teaching that is quickly gaining popularity in schools all over the world is the flipped classroom model, which involves having students participate in hands-on activities in the classroom while also watching instructional videos or hearing lectures electronically. To enhance learning outcomes for students, a relatively innovative approach to teaching and learning has been implemented. There is, however, little research on how Early Childhood Development (ECD) teachers see the flipped classroom approach. The study’s aim was to close this gap by examining ECD instructors’ perspectives in order to comprehend how the flipped classroom approach helps the learning of ECD students in centers. The concerns-based adoption model, a fundamental qualitative design, served as the study’s foundation. To learn more about how this technique is used by teachers and school officials, in-depth interviews and focus groups were conducted. Data analysis employed theme inductive methodology. Despite some difficulties, the results showed that most teachers thought the flipped classroom concept was quite beneficial. The findings also showed that teachers changed their roles, putting the students at the center of the learning process. By providing decision-makers and other interested parties with qualitative evidence to support the use of the flipped classroom model in ECD settings, this study helps to bring about social change. The study suggests that the flipped classroom can be used effectively at the ECD level if a stakeholder approach is used to accommodate the learners’ various demands. Future studies can concentrate on challenges associated with the use of the flipped classroom model in the teaching and learning process at the level of Early Childhood Development.
METALES TRAZAS (CU, CD, PB) EN AGUA, SEDIMENTO Y TEJIDO BLANDO DE LEUKOMA ASPERIMMA (LAMELLIBRANCHIA: VENERIDAE), EN LA PLAYA BIQUE, PACIFICO DE PANAMÁ.
Authors: Gómez H Juan Antonio , Leone Orlando , Villalaz Janzel , Goti Italo
Published: July 2023

Se colectaron muestras de agua, sedimento y tejido blando de Leukoma aspérrima, en tres estaciones perpendiculares a la línea de agua, en playa Bique, Panamá, para determinar la concentración de metales traza cobre (Cu), cadmio (Cd) y plomo (Pb), en marea baja de sicigia entre diciembre y junio de 2021. Los parámetros fisicoquímicos se determinaron con una sonda multiparamétrica, las muestras de las tres matrices fueron colectadas y preservadas hasta su tratamiento. Se observó mayor concentración de cobre y cadmio en agua, plomo en sedimento y cobre en el tejido blando. El cobre presentó valores más altos en agua en temporada seca, mientras que en sedimento y tejido blando predominó en la lluviosa, el cadmio mostró valores más elevados en temporada lluviosa en las tres matrices, mientras que la concentración de plomo fue mayor en agua y sedimento en la temporada lluviosa y en el tejido blando, durante la seca. Los valores encontrados de los tres metales trazan en tejido de L. asperrima no superan los límites permisibles para consumo humano según las normas internacionales.
Pasolini y la estética de lo político: el problema de la forma
Authors: Fasolino Dr. Rubén Carmine
Published: July 2023

A partir de algunos motivos presentes en Poesie in forma di rosa, La Divina Mimesis y, sobre todo, Petrolio, atenderemos algunos motivos de la propuesta estética de Pasolini en relación con la crítica de lo político. Lo que inicialmente parece una crítica o semiología de la sociedad y lo político se revela, con el tiempo, como un problema artístico en el cual el arte es en sí político y lo político es en sí artístico. Este asunto no es más que el de la forma tal y como aparece en las mencionadas obras del poeta.
PENGARUH KANDUNGAN SENYAWA BIOAKTIF EKSTRAK DAUN ANGSANA (Pterocarpus indicus) SEBAGAI INSEKTISIDA NABATI TERHADAP LARVA NYAMUK Aedes aegypti (L.) VEKTOR DENGUE DI BANJARMASIN
Authors: Syafitri Risma Alaika , Martha Sevia Audia , Ismaniar Nazula , Puteri Ananda , Muslim Muhammad , Risnawati Risnawati
Published: July 2023

Pengendalian nyamuk demam berdarah dengue (DBD) umumnya dilakukan menggunakan pestisida sintetik. Penggunaan pestisida sintetik dianggap efektif, praktis, manjur dan dari segi ekonomi lebih menguntungkan. Namun demikian penggunaan pestisida sintetik secara terus-menerus dan berulang-ulang dapat menimbulkan pencemaran lingkungan, kematian berbagai macam jenis makhluk hidup dan resistensi dari hama yang diberantas. Salah satu alternatif yang dapat digunakan dalam mengatasi permasalahan yang diatas adalah dengan penggunaan insektisida bahan alami (c) yaitu tumbuhan angsana (Pterocarpus indicus). Penelitian ini bertujuan untuk mengetahui pengaruh kandungan senyawa yang terkandung didalam ekstrak daun angsana (Pterocarpus indicus) maka dilakukan uji GCMS (Gas Chromatography Mass Spectrometry). Sampel dalam penelitian ini adalah larva nyamuk Aedes aegypti yang mana setiap kelompok perlakuan terdiri dari 25 ekor larva. Berdasarkan hasil penelitian diketahui bahwa terdapat pengaruh kandungan senyawa bioaktif ekstrak daun angsana (Pterocarpus indicus) sebagai insektisida nabati terhadap larva nyamuk Aedes aegypti (L.) vektor pembawa dengue di wilayah Banjarmasin dengan menggunakan pelarut etil asetat pada konsentrasi 0,25 %, 0,5%, dan 1%. Sedangkan konsentrasi yang paling efisien adalah 0,5% karena sudah dapat mematikan larva Aedes aegyti. Kemudian berdasarkan hasil analisis GCMS ekstrak etil daun Angsana (Pterocarpus indicus) menunjukkan beberapa senyawa yang berpotensi sebagai senyawa bioaktif larvasida, yaitu Palmatic Acid, Palmitate, Araldite 502, dan Lupenone
HUBUNGAN PERILAKU HIDUP BERSIH DAN SEHAT (PHBS ) IBU DENGAN KEJADIAN DIARE BALITA DI WILAYAH KERJA PUSKESMAS SUMBERSARI KABUPATEN JEMBER
Authors: Hendyca putra Dony setiawan
Published: July 2023

Perilaku Hidup Bersih dan Sehat (PHBS) sangat berpengaruh terhadap kejadian diare dan Penyakit diare pada balita dapat menyebabkan dampak negatife yaitu menghambat proses tumbuh kembang balita sehingga dapat menurunkan kualitas hidup balita. Faktor resiko lingkungan dan perilaku merupakan penyebab terjadinya diare. Untuk mengetahui ada atau tidak ada hubungan antara perilaku hidup bersih dan sehat ibu dengan kejadian diare pada balita di wilayah kerja puskesmas sumbersari kabupaten jember. Penelitian ini menggunakan metode survey analitik dengan pendekatan cross sectional. Penelitian dilakukan di wilayah kerja puskesmas sumbersari kabuapten jember. Besar sampel adalah 47 responden, diambil dengan menggunakan purposive sampling. Variabel penelitian meliputi : perlaku hidup bersih dan sehat ibu dan kejadian diare pada balita. Data perilaku hidup bersih dan sehat ibu diperoleh dengan kuesioner perilaku hidup bersih dan sehat . Data kejadian diare diperoleh dengan melihat laporan di posyandu. Uji statistic digunakan adalah uji Chi square. Populasi ibu degan Perilaku Hidup Bersih dan Sehat kategori kurang baik  25 (53,19%), cukup baik 7 (14,89%), dan baik 15 (31,91%). Selanjutnya data dianalisis dengan menggunakan Chi squase dan didapatkan Nilai p sebesai 0,000 (p<0,05) yang artinya terdapat hubugan antara perilaku hidup bersih dan sehat ibu dengan kejadian diare pada balita di wilayah kerja puskesmas sumbersari kabupaten jember. Disarankan pada penelitian ini bagi para ibu dengan balita riwayat diare untuk selalu peduli dan tanggung jawab terhadap perilaku hidup bersih dan sehat agar masalah diare pada balita dapat dicegah dengan baik.
No association between anthropometry and IQ in Czech preschool children
Authors: Malambo Chipo , Musálek Martin
Published: July 2023

Background: Previous research has suggested that body mass index (BMI) and body height are associated with intelligence quotient (IQ) in older children and adults. However, due to the limited number of studies in this age group, there is a lack of consensus on whether there are relationships between IQ and some anthropometric measures, including sex, among preschool-aged children.
Objectives: This study aimed to assess whether there is a significant relationship between sex, BMI, height IQ, and subsets of IQ among preschool-aged children.
Sample and Methods: 59 preschoolers aged 4.01 to 4.99 years were sampled from selected preschools in Prague. Data on sex, weight and height were collected, and IQ was assessed using the IDS-P. The data were processed using the St. Nicolas house analysis, t-tests and multiple regression.
Results: Multiple Regression Analysis and St. Nicolas house analysis failed to show any significant relations between sex, BMI, height, and IQ subtests score (p>0.05).
Conclusion: In this study, no significant associations were found between sex, BMI, height, and IQ in preschool-aged children. The relationships among sex, BMI, height, and IQ are more complex. For a better understanding, it is therefore essential to have larger sample sizes and to understand these interactions within context and with other confounding social-economic-political-emotional l (SEPE) variables, as suggested in previous studies.
Literature Review of Islamic Social Finance Contribution in Indonesia
Authors: Muhammad Rizal  , Marliyah
Published: July 2023

This study aims to review and map the concepts and principles of Islamic social finance in their contribution to the Indonesian economy, using qualitative methods with content analysis sourced from articles on the Google Scholar database. Data was obtained using the Publish or Perish (PoP) application for a period of 10 years (2012-2022) with the keywords concepts and principles of Islamic social finance, accessed on January 7 2023, 53 articles (population) were obtained and 20 articles were taken as samples, while data analysed 15 articles. The results of the study found that the most discussed themes were 1) Development of Islamic Social Finance with 5 articles (33%), Islamic Accounting with 3 articles (20%), Disclosure of Islamic Social Reporting with 3 articles (20%), Development of Microeconomics with 2 articles (13%) Performance of Islamic Social Finance (Public) 2 articles (13%). The concept of Islamic social finance recommended by the article in overcoming economic problems in Indonesia, among others; (1) Distribution of BLT originates from zakat, infaq, or alms; (2) Increasing waqf with cash waqf and productive waqf schemes; (3) Business capital assistance to Micro, Small and Medium Enterprises (UMKM); (4) Providing business capital with a qardhul hasan loan scheme; (5) Providing an understanding of Islamic economic and financial literacy; (6) Technology development
Importando para exportar, internacionalización de pequeñas firmas manufactureras en Bogotá, D.C. un estudio comparado
Authors: Valencia González Catherine , Páramo-Renza Edward
Published: July 2023

Dada la frágil y prolongada desaceleración del crecimiento económico mundial, los organismos multilaterales y gobiernos instan a formular políticas que puedan mejorar a largo plazo una diversificación económica eficaz, promoviendo la industrialización y la expansión internacional. Así el objetivo de este artículo es evidenciar la importancia de los procesos de importación, para apalancar la primera exportación de pequeñas firmas del sector manufacturero en Bogotá D.C. Para este fin se desarrolló un estudio de caso de tipo deductivo, a través de la investigación aplicada en la innovación de procesos, en la función de producción de bienes, y distribución y logística. La teoría abordada se enmarca en la internacionalización, vista desde el modelo Uppsala, y el modelo de innovación, asumiendo que la internacionalización es un proceso de innovación empresarial básica para la internacionalización de Pymes. Los resultados permitieron observar que indiferente a la actividad industrial que realicen, las firmas requieren importar bienes de capital o insumos para su proceso de producción. Las demoras en trámites aduaneros de importación retrasan los tiempos en los procesos productivos afectando los despachos de las mercancías en la exportación. Los destinos elegidos para la primera oferta exportable de estas industrias son países con los que Colombia tiene tratados de libre comercio.
Bird Diversity Changes of Pune Area
Authors: Ingalhalikar S. , Purandare R. , Nalavade S. , Dhole S.
Published: July 2023

Birds are extensively studied, particularly in Indian cities where they thrive due to abundant food from garbage dumps, ample nesting sites in planted trees, and the traditional goodwill towards all living beings. Pune, a city in India, supports over 330 bird species. Earlier works by various researchers have contributed to the understanding of Pune's bird fauna. The city and its surroundings host six major habitat types, with a majority of bird species residing in the wilderness zones. Changes in the bird fauna have been observed, including declines in some species due to factors such as urbanization and environmental changes. Monitoring and conservation efforts are essential to protect the diverse avifauna in urban areas.
Analysis on the Risk of Turkey Falling into the "Middle Income Trap"
Authors: Dai Xiaopeng
Published: July 2023

In 2007 Turkey was classified as an "upper-middle-income country" by the World Bank, but it soon became Mired in bottlenecks. The main reasons for Turkey to fall into this trap are: domestic and foreign political instability, industrial structure imbalance, insufficient innovation-driven capacity, weak financial system, etc., which hinder Turkey's productivity improvement and economic growth, but also hinder social development. For developing countries, on the one hand, they should properly handle their internal diplomatic relations and create a stable environment for their own economic development. On the other hand, we should vigorously develop human capital, accelerate scientific and technological innovation, and at the same time control the freedom of financial markets and control the scale of foreign debt.
No evidence of relationship between colorectal cancer susceptibility and ERCC2 gene polymorphisms
Authors: Farhad Rand , Saleh Eman , Alsammarraie Ahmed
Published: July 2023

Background: Excision repair cross-complementing group 2 gene (ERCC2) polymorphisms have been linked as being a risk factor for colorectal cancer (CRC) emergence. However, data from several studies are contradictory. To validate genetic biomarkers of the CRC; the impact of the following ERCC2 polymorphism (rs1799793 and rs238406) was examined on CRC susceptibility among sample of Iraqi population. Methods: A total of 126 subjects were enrolled in this case control study; 78 CRC patients and 48 apparently healthy individuals who are age, gender, smoking status and BMI matched. Polymerase chain reaction (PCR) was used for genotyping, followed by sequencing then the association between genetic polymorphisms and CRC risk was investigated. Results: No associations were detected between ERCC2 genotypes or haplotypes and CRC susceptibility. Even though there was strong linkage disequilibrium (D′= 0.82). After stratification according to participants’ demographics, no effects were observed for age, gender, smoking status and BMI. Conclusions: Taken together the following results suggest that ERCC2 polymorphisms do not influence CRC development.
Technological prospecting of macaúba (Acrocomia aculeata) in Brazil in the 21st century
Authors: Rodrigues Artur Saturnino , Aguiar Rogério Marcos Ribeiro , Maro Thiago Arrais , Roa Juan Pedro Bretas , Nelson David Lee , Benassi Vivian Machado
Published: July 2023

Macaúba is a fruit found in several regions of the Brazilian territory and stands out for producing an oil with potential characteristics for use as a raw material in industries in different areas such as in the production of biodiesel, biokerosene, organic fertilizers and animal ration. An advanced search was performed in the title and abstract fields of the National Institute of Industrial Property (INPI) database. Patents related to macaúba were grouped by the number of files per decade, number of patents by holder and characteristics of granted patents. With the insertion of this mechanism, the most recent applications were listed through a mapping of patents involving macaúba and the main sectors that invested in the fruit. It was certified that, between 2000 and 2021, thirty patents related to macaúba were registered, and nine were granted. Minas Gerais stood out in technological development, especially after the creation of a public policy for the development of this species and its use, the Pro-macaúba Law (Law No. 19,485/2011). It is the state with the most deposited patents.
Research on Cross-cultural Adaptation Management of International Students Studying in China from the Perspective of Psychological Contract
Authors: Fu Naiyuan , Si Xiaopeng , Xie Yan , Shan Bin
Published: July 2023

This study used SPSS software to conduct descriptive statistics, correlation analysis and regression analysis to explore the relationship between psychological contract and cross-cultural adaptation of international students in China, and found that school reality responsibility, school development responsibility and student development responsibility have significant positive effects on the psychological adaptation of international students in China, and all four dimensions of the psychological contract have significant positive effects on the study adaptation of international students in China, based on this result this Based on the results, this study proposes corresponding management measures and suggestions from the perspective of the psychological contract to improve the cross-cultural adaptation ability of international students so that they can adapt to life in China more quickly and complete their studies successfully.
Water soluble fertilizers in horticultural crops— An appraisal
Authors: MALHOTRA S K
Published: July 2023

Horticultural crops have now attained a status, parallel to not only field crops, but stake strong claim of offering nutritional security, thereby, cutting the unnecessary load on consumption of cereals. However, raising productivity of horticultural crops is still a constraint. One of the prime reasons is the abysmal use of fertilizers, hardly 10% of total fertilizer use is diverted towards the share of horticultural crops. Of different fertilizers, liquid fertilizers are again a special class of fertilizers, hold very strong promise in protected cultivation, hydroponic/aeroponic or even open field hydroponic for perennial fruit crops. The liquid fertilizers, as special class of fertilizers provide an enormous possibility of tailoring nutrient use across critical growth stages, a pre-requisite for better nutrient-use-efficiency. Customized fertilization/fertigation is another potential reality, besides its suitability in site specific nutrient managements. In this background, these issues have been addressed in this review.