bluuebunny/crossref_metadata_2025 huggingface dataset:
QUALITY OF LIFE IN HYPERTENSIVE PATIENTS WITH METABOLIC SYNDROME: INTERRELATION WITH MARKERS OF SYSTEMIC INFLAMMATION
Authors: Bespalova I. D. , Bychkov V. A. , Kalyuzhin V. V. , Ryazantseva N. V. , Medyantsev Yu. A. , Osikhov I. A. , Murashev B. Yu.
Published: June 2020

Object of research: to study the interrelation of activity of systemic inflammatory response and quality of life (QOL) and evidence of metabolic disorders in hypertensive patients with metabolic syndrome (MS).

Material and methods.We carried out a study of 86 patients with hypertensive disease of II stage in combination with MS and 18 volunteers, who formed the control group. Along with a complete clinical, laboratory and instrumental examination, taken in a specialized cardiology clinic, the study of QOL using the MOS SF-36 questionnaire was carried out, as well as the research of activity of systemic inflammato-ry response.

Results.We determined the reverse correlative interrelation of QOL indicators with all MS components, such as abdominal obesity, hyperglycemia, hypertriglyceridemia, the degree of arterial hypertension, but also with the level of markers of systemic inflammation (C-reactive protein, neopterin and fibrinogen), hyperinsulinemia and hyperleptinemia. It was found out that physical functioning (PF) has the strongest interrelations with the maximum number of clinical and laboratory indicators of MS and all the studied markers of systemic inflammation.
COCHLEAR IMPLANTATION PREVALENCE IN ELDERLY
Authors: Starokha A. V. , Balakina A. V. , Litvak M. M. , Knipenberg A. E. , Shcherbik N. V. , Druzhinin A. I.
Published: June 2020

Current paper describes an experience of cochlear implantation in elderly. Cochlear implantation has become a widely accepted intervention in the treatment of individuals with severe-to-profound sensorineural hearing loss. Cochlear implants are now accepted as a standard of care to optimize hearing and subsequent speech development in children and adults with deafness. But cochlear implantation affects not only hearing abilities, speech perception and speech production; it also has an outstanding impact on the social life, activities and self-esteem of each patient. The aim of this study was to evaluate the cochlear implantation efficacy in elderly with severe to profound sensorineural hearing loss. There were 5 patients under our observation. Surgery was performed according to traditional posterior tympanotomy and cochleostomy for cochlear implant electrode insertion for all observed patients. The study was conducted in two stages: before speech processor’s activation and 3 months later. Pure tone free field audiometry was performed to each patient to assess the efficiency of cochlear implantation in dynamics. The aim of the study was also to evaluate quality of life in elderly with severe to profound sensorineural hearing loss after unilateral cochlear implantation. Each patient underwent questioning with 36 Item Short Form Health Survey (SF-36). SF-36 is a set of generic, coherent, and easily administered quality-of-life measures. The SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The eight sections are: physical functioning; physical role functioning; emotional role functioning; vitality; emotional well-being; social role functioning; bodily pain; general health perceptions. Our results demonstrate that cochlear implantation in elderly consistently improved quality of life and enhance the efficiency of audiologic rehabilitation.
OPPORTUNITIES OF BIOMEDICAL USE OF CARBON NANOTUBES
Authors: Mitrofanova I. V. , Milto I. V. , Suhodolo I. V. , Vasyukov G. Yu.
Published: June 2020

Nanomaterials  –  materials,  whouse  structure  elements  has  proportions  doesn’t  exceed  100  nm.  In superdispersed state matter acquire new properties. In the last decade, carbon nanotubes become the most popular nanomaterials, that cause attention of representatives of various scientific field. The сarbon nanotubes offer new opportunities for biological and medical applications: imaging at the molecular, cellular and tissue levels, biosensors and electrodes based on carbon nanotubes, target delivery of various substances, radiation and photothermal therapy. The most promising of carbon nanotubes in the context of biomedical applications is their ability to penetrate the various tissues of the body and carry large doses of agents, providing diagnostic and therapeutic effects. Functionalized nanotubes are biodegradable. Other current direction of using carbon nanotubes in medicine and biology is to visualize objects on the molecular, cellular and tissue level. Associated with carbon nanotubes contrasting substances improve the visualization of cells and tissues, which can detected new patterns of development of the pathological process. Due to the vagueness of the question of biocompatibility and cytotoxicity of carbon nanotubes possibility of their practical application is hampered. Before the introduction of carbon nanotubes into practical health care is necessary to provide all the possible consequences of using nanotubes. High rates of properties and development of new nanostructures based on carbon nanotubes in the near future will lead to new advances related to the application and development of new parameters that will determine their properties and effects. In these review attention is paid to the structure, physico-chemical properties of nanotubes, their functionalization, pharmacokinetics and pharmacodynamics and all aspects of using of carbon nanotubes.
ADVANCED MEDICAL INFORMATION TECHNOLOGY 1.0 PROGRAM APPLICATION IN THE ANALYSIS OF PATIENTS WITH THE AGE-RELATED MACULAR DEGENERATION
Authors: Melehin Ye. V. , Khoroshikh Yu. I. , Krylova A. A.
Published: June 2020

Developed medical information system (MIS) that enables you to automate and organize the processing of clinical database in medical institutions (MIS). In a study using IIAs analyzed data of dynamic observation of patients with various types of exudative edematous macular degeneration on the background of peripheral uveitis 376 people (406 eye). For professional computer analysis of the data used in the statistical package SPSS for Windows», which enabled to evaluate the effectiveness of a new method of treatment of patients with age-related macular degeneration.
IMMUNOLOGICAL AND METABOLIC FACTORS INTERACTION IN THE DEVELOPMENT AND PROGRESSION OF MICROVASCULAR COMPLICATIONS IN LATENT AUTOIMMUNE DIABETES OF ADULTS (LADA)
Authors: Saprina T. V. , Prokhorenko T. S. , Lazarenko F. E. , Vorozhtsova I. N. , Ryazantseva N. V.
Published: June 2020

Some researchers found that the development of microvascular complications (nephropathy, retinopathy) with latent autoimmune diabetes adults (LADA) occurs much earlier than in type 1 diabetes mellitus. The research devoted to the study of the spectrum and the time of development of microangiopathy in patients with latent autoimmune diabetes of adults, compared to patients with type 1 and 2 diabetes mellitus. Also studied immunological factors (cytokine secretion of mononuclear leukocytes) as one of the possible mechanisms of diabetic angiopathy progression. It has been shown that in LADA, as in patients with type 2 diabetes mellitus, the development of microvascular complications (nephropathy, retinopathy) occurs much earlier than in type 1 diabetes mellitus (after a 4-year course of the disease) due to a sharp decline in the serum concentration of C peptide. Thus in patients with LADA, having microvascular complications in the supernatants of cell cultures of mononuclear leukocytes determined a significant increase in the concentrations of cytokines IL-2, IL-4, TNFα.
CHARACTERISTIC OF OSTEOPENIC SYNDROME IN PATIENTS WITH PATHOLOGY OF THE THYROID GLAND USING ULTRASOUND OSTEOMETRY
Authors: Pavlenko O. A. , Nochevnaya L. B. , Zavadovskaya V. D. , Kilina O. Yu.
Published: June 2020

The study was conducted to investigate state of bone metabolism and bone strength in various pathologies of the thyroid gland. We revealed violations of bone remodeling with a shift in the direction of resorption and formation of reduction of bone strength with in patients with hyperthyroidism and hypothyroidism.
THE REFERENCE VALUES OF REPRODUCTIVE HORMONES IN 1–3 MONTHS HEALTHY BOYS
Authors: Raygorodskaya N. Yu. , Bolotova N. V. , Zakharova N. B. , Lvova O. V.
Published: June 2020

The postnatal activity of hypothalamic-pituitary-gonadal axis in first few months of life is defined as mini-puberty.  In  article  the  dates  of  Enzyme  Immuno  Assays  of  the  serum  gonadotropins  and reproductive hormones in 40 healthy boys ages 1–3 month are represented. In results we detected the reference values of serum LH, FSH, testosterone, DGA-S, androstendyone, dyhydrotestosterone, antiMulirean  factor  in  1–3  month  aged  boys.  The  obtained  dates  are  comparable  to  puberty values  of reproductive hormones in boys.
PALLIATIVE RESECTIONS OF A LIVER USING CRYODESTRUCTION FOR THE PATIENTS WHO HAVE BEEN REPEATEDLY OPERATED FOR ALVEOCOCCOSIS
Authors: Alperovich B. I. , Zaytsev I. S.
Published: June 2020

The purpose of work was the assessment of influence of a palliative resection of a liver with application of cryodestruction and without cryodestruction application on the remote results of treatment of the patients who have been repeatedly operated for alveococcosis.The analysis of surgical treatment of 14 patients operated repeatedly for alveococcosis of a liver is carried out. Patients were operated in the complicated stage of a disease in the presence of germination of a parasite in caval and/or portal gate of organ. Primary interventions were various – a diagnostic laparotomy, a cytoreduction and a marsupialization of a parasite, a liver resection. All patient at repetition intervention executed palliative resections of a liver. Resections were carried out by a clinic technique with imposing the ginglymoid of ligatures on remaining tissue of a liver at distance of 2–3 cm from the deleted parasitic knot taking into account a segmentary structure of organ. At all patients on "dangerous zones" (a zones of gate of a liver, a hepatoduodenal ligament) plates of parasitic fabric of various sizes from 1  2 cm to 2  4 cm were left. At 10 patients they were exposed to cryodestruction. The exposition in one point made from 1 to 2 minutes at a temperature –196 С. Postoperatively, patients received a dose of 10 mg/kg albendazole.Development of hepatic insufficiency after palliative resections of a liver is noted in one case. Lethal outcomes weren't.All patients for convenience of the analysis were divided into two groups: group of patients without application of cryotechnologies (n = 4) and group of the patients operated with application of cryodestruction (n = 10). Efficiency of palliative resections estimated on a median of survival of patients. Calculation of survival carried out Kaplan–Meier's method. The survival median in groups made 12 and 17 years respectively.When comparing survival of patients by Gehan's test with Yates's correction distinction of survival in two selections are statistically significant (z = 2,94; p < 0,005).Among patients repeatedly operated for alveococcosis when involving in parasitic process of gate of a liver, lack of possibility of prosthetics of vascular structures and developments of a compensatory hypertrophy of not struck departments of body the palliative resection allows to achieve survival of 50% of patients more than 16,8 years.Cryodestruction is the effective and safe method, allowing to increase survival of patients after a p alliative resection of a liver, through the destruction left in the area of the liver gate parasitic tissue sections.
ACTIVATION REACTION ON THE ELECTROENCEPHALOGRAM IN SUBSTANCE DEPENDENT PATIENTS: LINKS TO ADDICTION STUDIES AND PSYCHOLOGICAL FACTORS AND CHANGES IN NEUROFEEDBACK TRAINING
Authors: Melnikov M. E
Published: June 2020

Depth of activation reaction (α-activity suppression during the eyes-opening task) is considered to be an important quantitative characteristic of α-band brainwaves. Activation reaction was assessed from O1 and O2 leads in 31 male substance dependent subjects. In 7 cases it was measured twice: before and after α- or β-brainwave biofeedback training. The correlations were found between grade of α suppression in eyes-opening task and attitude towards disease and treatment, personality maturity, and level of pathological personality traits. Activation reaction was significantly improved by α-training and non-significantly diminished after β-1-training.
PALMITIC AND OLEIC ACIDS AND THEIR ROLE IN PATHOGENESIS OF ATHEROSCLEROSIS
Authors: Titov V. N. , Dygai A. M. , Kotlovskiy M. Yu. , Kurdoyak Ye. V. , Yakimenko A. V. , Yakimovich I. Yu. , Aksyutina N. V. , Kotlovskiy Yu. V.
Published: June 2020

On the basis of phylogenetic theory of general pathology, the cause of a noninfectious disease whose occurrence in a population is more than 5–7% is an impaired biological function or reaction to the environment. From the general biology viewpoint, high mortality rate related to cardio-vascular diseases and atherosclerosis (intercellular deficiency of polyenic fatty acids (PFA)) is just extinction of the Homo sapiens population upon adaptation to new environmental factors. The biological function of throphology (feeding) and biological reaction of exotrophy (external feeding) are impaired in several aspects, the major of which is nonphysiologically high dietary content of saturated fatty acids, primarily, of palmitic fatty acid (FA). The lipoprotein system formed at early stages of phylogenesis cannot transport and provide physiological deposition of great amounts of palmitic FA, which leads to the development of an adaption (compensatory) and accumulation disease. This results in hypermipidemia, impaired bioavailability of PFA to cells, compesatory production of humoral mediators from ω-9 eicosatrienoic mead FA, disorders in physiological parameters of cell plasma membrane and integral proteins, nonphysiological conformation of apoВ-100 in lipoproteins, formation of ligandless lipoproteins (biological litter) and impairments in the biological function of endoecology, utilization of ligandless lipoproteins in arterial intima by phylogenetically early macrophages that do not hydrolyze polyenic cholesterol esters, increase in the intensity of the biological reaction of inflammation, and destructive and inflammatory lesions in arterial intima of an atheromatosis or atherothrombosis type. Atheromatous masses are catabolites of PFA which were not internalized by phylogenetically late cells via receptor-mediated pathway.
STATUS OF HEALTH IN THE REGIONS OF SIBERIA AND THE FULFILLMENT OF THE MESSAGE OF THE PRESIDENT OF THE RUSSIAN FEDERATION TO THE FEDERAL ASSEMBLY OF THE RUSSIAN FEDERATION FROM DECEMBER 12, 2013
Authors: Shalygina L. S. , Sadovoy M. F. , Finchenko Ye. A. , Mamonova Ye. V. , Tsytsorina I. A.
Published: June 2020

The aim of the study was to identify the key problems of regional health services in the Siberian Federal district and justification of the priority directions of their decision. For the first time using the method of expert estimations conducted a study of health problems in the Federal district, identified key issues, as well as justifies the priority directions of their decisions. The study was conducted on the basis of statistical materials of the health authorities of the regions of Siberian Federal district, as well as expert assessments. Identified key health issues and priorities of their decision. Based on the systematic work of the expert community and across government levels defined key for the regions of Siberia health problems and justify the priority directions of their solutions tailored to focus efforts in the social sphere, which will allow to coordinate policies in the health sector on the territory of the Siberian Federal district, which in turn, will increase its effectiveness.
ASSOCIATION OF ADRA2B POLYMORPHISM WITH RISK FACTORS FOR CARDIOVASCULAR DISEASES IN NATIVE POPULATION OF MOUNTAIN SHORIA
Authors: Mulerova T. A. , Yankin A. Yu. , Rubtsova Ye. V. , Kuzmina A. A. , Orlov P. S. , Tatarnikova N. P. , Maksimov V. N. , Voevoda M. I. , Ogarkov M. Yu.
Published: June 2020

Study objectives: examine the frequency of genotypes and alleles of I/D polymorphism of gene ADRA2B of native people living in Mountain Shoria (the Shors), as well as their association with risk factors for cardiovascular diseases.Material and methods. Overall 221 native people of Shoria were examined. The average age is51.07 ± 1.46 among males, 52.93 ± 0.96 among females (p = 0.286). Anthropometric characteristics, lipid levels of blood and I/D polymorphism of ADRA2B were studied.Results. DD genotype of the gene ADRA2B in the native population of the Shor people is associated with adiposis and high index of "waist/hip", hypertriglyceridemia. The average values of Quetelet index is higher in carriers of this genotype compared with carriers of genotype ID. Average waist indications in homozygous insertions were lower than those in homozygous deletions and heterozygotes. Patients with genotype DD have higher average levels of triglycerides, atherogenic index, cholesterol, very low density lipoproteins.Conclusion. DD allele ADRA2B genotype is responsible for adiposis and high levels of TG among native population of Shoria.
SURGICAL TREATMENT OF DISTROPHICAL BONE KISTS BY TITANIUM NIKELID POROUS MATERIALS IN CHILDREN
Authors: Slizovskiy G. V. , Sitko L. A. , Kuzhelivskiy I. I.
Published: June 2020

The article presents the results of bone kists treatment by porous granular titanium nikelid materials. A comparative examination with standard treatment technology group demonstrated high efficiency of a proposed method. Porous granular titanium nikelid materials possess mechanical strength, optimization of regeneration  at the expense of osteoinductivity and  allow you  to  effectively fill the cavity with a complex anatomical structure.
THE HISTORICAL REVIEW AND TRENDS IN THE DEVELOPMENT OF SURGICAL TREATMENT OF RECCURENT SHOULDER INSTABILITY
Authors: Prokhorenko V. M. , Filipenko P. V. , Fomenko S. M.
Published: June 2020

An analysis of literature data was conducted to characterize the main current stage of development and formation of diagnosis and treatment of shoulder instability. The purpose of this review was to determine the main directions in the treatment of recurrent shoulder instability and problematic issues that require further scientific research. The main results of patients monitoring that were undergone different types of arthroscopic treatment were presented. The present level of diagnostics allows to accurately define the indications for surgical treatment. A method of glenoid bone defect reconstruction is presented that based on careful preoperative planning. Determination of possible risk factors and every possible pathogenesis link and individual preoperative planning are the main tasks in the prevention of the shoulder instability recurrences.
MOLECULAR GENETIC STUDIES OF COMORBIDITY
Authors: Bragina Ye. Yu. , Freidin M. B.
Published: June 2020

This review focuses at the problem of the genetic basis of comorbidity. We discuss the concepts and terms relating to combinations of diseases. The guidelines of the study of comorbidity using modern high throughput methods and approaches of genetics, molecular biology and bioinformatics are designated. In this review we present results of studies showing genetic specificity for the combined phenotypes dif-ferent from the isolated disease, we considergene-gene and gene-environment interactions in comorbidity. We also discuss the role of single nucleotide polymorphisms and structural genome variations in the development of comorbidity. Own results of researching shared genes of inversely comorbid diseases like as bronchial asthma and tuberculosis are presented.
Le zinc dans l’alimentation du porc : oligo-élément essentiel et risque potentiel pour l’environnement
Authors: REVY P.S. , JONDREVILLE C. , DOURMAD J.Y. , NYS Y.
Published: June 2020

Le zinc est un oligo-élément essentiel qui intervient dans la plupart des fonctions biologiques de l’animal. La perte d’appétit, la diarrhée, le retard de croissance ou la parakératose sont les principaux symptômes d’une carence en zinc qui peuvent apparaître chez le porc recevant une alimentation non supplémentée en zinc. La méconnaissance des besoins en zinc du porc et des facteurs de variation de sa disponibilité conduit à l’incorporer de manière excessive dans les aliments. Cette pratique génère des rejets importants et augmente le risque de pollution des sols cultivés. L’ajustement des apports de zinc aux besoins de l’animal et l’amélioration de sa disponibilité sont des solutions qui permettent d’en réduire les apports. Une revue des données de la littérature nous permet d’estimer les besoins en zinc du porc en fonction du poids vif. L’utilisation d’additifs, notamment de phytase microbienne, permet d’améliorer la disponibilité du zinc. A partir des résultats de la littérature, nous estimons que l’activité de 1000 unités de phytase microbienne par kg d’aliment est équivalente à une addition de 24 et 19 mg/kg de zinc sous forme de sulfate chez le porcelet de respectivement 15 et 25 kg. Ces estimations sont à valider expérimentalement. D’autres voies d’amélioration de la disponibilité du zinc doivent également être explorées.
Typologie et ontogenèse des fibres musculaires chez les oiseaux
Authors: BERRI C. , DUCLOS M.J.
Published: June 2020

Cet article fait partie du Dossier Typologie et ontogenèse des fibres musculaires chez différentes espèces d’intérêt agronomique.
Impact of Lockdown due to COVID-19 Outbreak : Lifestyle Changes and Public Health Concerns in India
Authors: Narayanan Latha , Pandit Mansi , Basu Subhro , Karmakar Arijeet , Bidhan Vanshika , Kumar Hrithik , Brar Kousheen
Published: June 2020

The emergence of COVID -19 pandemic has severely impacted individuals from all walks of life. The rapid spread of the disease to nearly all parts of the country has posed enormous health, economic, environmental and social challenges to the entire human population. In the absence of any effective drugs and vaccines for treatment, social distancing and other preventive measures are the only alternatives. Lockdown is among one of the options suggested by WHO to reduce spread of the virus. India was quick to close its international borders and enforce the world’s largest COVID lockdown on March 22, 2020. The present study attempts to highlight the impact of imposed nationwide lockdown on society and environment alike along with analysis of lifestyle changes. The study was based on an online survey using a structured questionnaire with over 1000 responders across the country. The pandemic situation demands a certain way of shaping the society to reduce virus spread and safeguard oneself. In this study, we analysed the changes that the society has undergone during lockdown to mitigate the spreading of the infection. We also addressed the changes that have become part of our lives during lockdown – hygiene and health consciousness, work from home (WFM), online teaching, digital shopping, changing internet habits and societal changes.
“AKU MASIH CINTA INDONESIA”: STUDI PENDIDIKAN KARAKTER NASIONALISME DALAM KELUARGA PADA ANAK-ANAK BURUH MIGRAN INDONESIA DI MALAYSIA
Authors: Prasetyo Dimas Teguh , Tarma  , Putri Vera Utami Gede
Published: June 2020

Fenomena migrasi yang dilakukan oleh para buruh migran Indonesia di Malaysia menyisakan cerita terutama bagi anak-anak yang lahir dan ikut bersama orangtuanya bermigrasi. Orangtua yang memiliki fungsi pendidikan dalam keluarga dituntut mampu memberikan pendidikan informal kepada anak-anak mereka untuk selalu mencintai dan menanamkan jiwa nasionalisme dalam diri mereka. Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh pendidikan karakter nasionalisme dalam keluarga terhadap karakter nasionalisme pada anak-anak buruh migran Indonesia di Malaysia. Studi ini merupakan penelitian korelasional yang dilakukan kepada 30 anak-anak di PKBM X Estate, Bintulu, Serawak, Malaysia. Hasil menunjukan bahwa terdapat pengaruh yang positif pendidikan karakter nasionalisme dalam keluarga terhadap karakter nasionalisme anak. Koefisien determinasi yang diperoleh dalam penelitian ini sebesar 25,50% yang menunjukkan bahwa besarnya karakter nasionalisme anak yang dipengaruhi oleh pendidikan karakter nasionalisme dalam keluarga. Hal tersebut menunjukan bahwa keluarga terutama orangtua memiliki peran yang penting dalam menciptakan dan mengembangkan karakter nasionalisme anak meskipun sedang berada dan tinggal di luar Indonesia.

Kata Kunci: anak buruh migran, fungsi keluarga, karakter nasionalisme, pendidikan karakter 

 

"I Still Love Indonesia": Study of Nationalism Character Education in Families in Indonesian Migrant Worker in Malaysia

Abstract

The migration phenomenon conducted by Indonesian migrant workers in Malaysia leaves stories especially for children born and who are with their parents migrating. Parents who have the function of education in the family are required to provide informal education to their children to always love and instill the soul of nationalism within them. This study aims to determine and analyze the influence of character education of nationalism in the family against the character of nationalism on the children of Indonesian migrant workers in Malaysia. This is a correlational study conducted to 30 children in Community Learing Center (CLC) X Estate, Bintulu, Sarawak, Malaysia. The result shows that there was a positive correlation between character education of nationalism in the family and nationalism character of migrant labor children. It shows that family especially parents have important  role to create and develop child nationalism whether they live in out of Indonesia.

Keywords: character education, child labor migran, family function, nationalism character
Is Blastomycosis Endemic in Upstate New York?
Authors: Murtaza Hamza , Arain Abdul Rehman , Li Hua , Tobin Ellis H. , DiCaprio Matthew R.
Published: June 2020

Case:

We describe a case of biopsy-proven blastomycosis in a patient residing in Upstate New York with osseous and skin lesions and no pulmonary or constitutional symptoms. The patient had a rapid resolution of symptoms after the initiation of antifungal treatment, followed by curettage and cementation of her distal femoral lesion.

Conclusions:

Orthopaedic surgeons should be aware of the presence of blastomycosis in nonendemic areas, especially since bone involvement may be the predominant manifestation. Tissue should be submitted for both histologic and microbiologic analysis. Antifungal therapy and surgical management if needed can result in a good outcome.
Pengaruh Kemampuan Berpikir Kreatif Terhadap Kemampuan Mengelolah Lingkungan Hidup dengan Pendekatan Berbasis Masalah pada Matakuliah PKLH
Authors: Ahmad Deni Nasir
Published: June 2020

The purpose of the research activity is to know whether there is an influence of the ability to think creatively on the ability to manage the environment with a problem-based approach to the PKLH course. The method in this study is a quasi-experimental method, the sample in research activities is physics education students, namely R4A class totaling 29 people. While the data collection techniques used in this study are questionnaires given to determine students 'creative thinking abilities and scoring instruments from student scientific reports to determine students' abilities in managing the environment. The simple linear regression test was used to examine the research hypothesis. The results showed that there was an indirect effect between the ability to think creatively on the ability to manage the environment with independent assignments in the PKLH courseshown from the hypothesis test that is fcount <ftabel that is equal to 0.139 <3.37.
The Influence of Skills of Integrated Character Science Processes on The Results of Physics Learning
Authors: Ermawati Imas Ratna
Published: June 2020

This study was conducted to find out whether the integrated science process skills test character to the character influences the learning outcomes of high school physics. The study was conducted at SMAN 1 Maumere in class XI MIA 1 as an experimental class and XI MIA 2 as a control class with material namely optical instruments in the even semester of 2017/2018 school year. The research method used is an experiment with  Quasi  Experimental  Quasi  Experimental  research  design  used,  namely  The  None  Equivalent  Pretest- Posttest Control Group Design, while the research subject retrieval technique is Simple Random Sampling. The research  subjects  used  were  33  students  both  from  the  experimental  class  and  the  control  class.  Before  the research  instrument  is  used,  the  validity  and  reliability  test  is  first  tested.  In  the  validity  test  using  Pearson Product Moment correlation,  there  were 24  questions  tested  and  obtained  results  in 18  valid  questions and  6 drop questions. In the reliability test using the Cronbach Alpha formula get results r count = 0.870> 0.329; so that the instrument is said to be reliab with high interpretation. The next step is data retrieval using instruments that  are  valid  and  reliable  and  then  performed  an  analysis  prerequisite  test  in  the  form  of  normality  test  and homogeneity test. In the test for normality using chi squared results are obtained; with a significant level of α = 0.05 and the number of samples was 33 students in the experimental class and in the control class which meant that  the  experimental  and  control  classes  were  normally distributed.  In  the  homogeneity test  using  the  F  test results obtained,; with a significant level of α = 0.05 and a total sample of 33 students, the research class is a homogeneous class. In the last stage the hypothesis test with the t-test is obtained and the results are obtained; with a significant level of α=0.05 and a total sample of 33 students, the integrated science process skills of the characters developed affected the learning outcomes of physics.
Hubungan Kerja Keras dan Sikap Siswa dalam Pembelajaran IPA
Authors: Sari Nirmala , Putri Yolanda Eka , Jannah Nurdatul , Puspitasari Tari Okta
Published: June 2020

This study aims to determine the relationship of hard work to the attitudes of students in science subjects at SMPN 4 Muaro Jambi. The research design used is associative quantitative with correlation design. The sampling technique used was total sampling with a total sample of 126 students. The analysis technique used is descriptive statistics and inferential statistics. Descriptive statistics display the mean, mode, minimum and maximum values. While the inferential statistics used are product-moment correlation tests. Based on the results of this study, it was found that there is a relationship of hard work towards students' attitudes in science subjects that can be seen from the Sig. (2-tailed) of 0.010 <0.05 which states there is a relationship between attitude to student hard work. Then the correlation coefficient of 0.668 which states that the level of correlation is strong.
Avicenna’s Proof for God’s Existence: the Proof from Ontological Considerations
Authors: Lasica Vladimir
Published: June 2020

This paper argues that there is only one proof for God’s existence in Avicenna, and only one way for establishing the proof within his metaphysical system. This metaphysical proof is essentially derived from a priori notions, among which the notion of existence (wujūd) has the central role. Avicenna’s proof is structured in such a way that all its concepts are either derived from the meaning of ‘existence’ or are connected with this meaning. In this sense Avicenna’s proof sets out a scenario of discursive a priori knowledge established purely on considerations of fundamental ontological meanings such as ‘existence’, ‘existent’, ‘thing’, ‘necessary’, ‘possible’, ‘impossible’, ‘one’ and ‘cause’.
¿Esse o existencia? La distinción real entre Lawrence Dewan y Étienne Gilson
Authors: Serra Pérez Manuel Alejandro
Published: June 2020

Uno de los temas más debatidos en el período inmediatamente posterior a la muerte de Tomás de Aquino fue cómo interpretar fielmente de acuerdo a sus textos el concepto de esse, dada la cualidad metafísica particular que éste adquiría en esta nueva ontología. Teniendo en cuenta que durante la escolástica los pensadores trataban de servirse de la filosofía como instrumento para explicar la fe, la comprensión del esse como distinto realmente de la esencia, fue el centro del debate por ser la base del principal argumento para mostrar la diferencia ontológica entre Dios y las criaturas.
Cecilia Panti and Nicola Polloni (eds.), Vedere nell’ombra. Studi su natura, spiritualità e scienze operative offerti a Michela Pereira, Micrologus Library 90, Firenze, SISMEL – Edizioni del Galluzzo, 2018, 430 pp., ISBN: 9788884508133. Cloth €62
Authors: CESCO-FRARE LAURA
Published: June 2020

Reseñado por LAURA CESCO-FRARE University of Salerno l.cescofrare@studenti.unisa.it
Flavia Buzzetta, Magia naturalis e scientia cabalae in Giovanni Pico de la Mirandola. Studi pichiani 20, Firenze, Leo S. Olschki, 2019, x-344 pp., ISBN: 9788822266309. Cloth €35
Authors: ORTIZ CARLOS
Published: June 2020

Reseñado por CARLOS ORTIZ DE LANDÁZURIUniversidad de Navarra, Pamplona, EScortiz@unav.es
Budidaya Pakan Lebah Trigona sp. dengan Apiculture Agroforestry System di Kelurahan Anjungan Melancar, Kecamatan Anjungan Kabupaten Mempawah
Authors: Syaifudin Syarif Muhammad
Published: June 2020

Mitra berada di Kabupaten Mempawah yaitu Desa Anjongan Melancar di Kecamatan Anjongan. Salah satu usaha budidaya yang kini mulai diminati oleh masyarakat terutama di Kelurahan Anjungan melancar dan Desa Galang adalah  Budidaya madu Kelenceng atau Kelulut (Trigona sp.). Dalam kegiatan Pengabdian kami memberikan dua hal yang menjadi solusi permasalahan mitra di Anjungan Melancar yaitu teknis budidaya pakan lebah kelulut dengan menggunakan Apiculture Agroforestry System dan edukasi perbaikan manajemen pemasaran madu kelulut. dalam hal Pemasaran masyarakat sudah menggunakan media sosial dan sebagai media pemasaran, dan sebagian besar produk madu yang dihasilkan sudah memiliki branding. Sehingga kegiatan edukasi pemasaran difokuskan tentang bagaimana masyarakat dapat mengelola dinamika persaingan antar peternak dan prilaku konsumen madu kelulut. Sedangkan dari aspek budidaya tim memberikan bantuan bibit sebanyak 1200 bibit pohon berbunga dari jenis Kaliandra, tanah mineral Podsolik Merah Kuning (PMK), dan alat-alat pertanian untuk mendukung perawatan tanaman. Tim pelaksana pengabdian mengadakan kegiatan bimbingan teknis tentang bagaimana menanam di lahan gambut untuk jenis pohon dan pola penanaman yang tepat. Hasil pemantauan terhadap hasil yang diperoleh mengindikasikan bahwa masyarakat memahami dan dapat mengaplikasikan Apiculture Agroforestry System. jenis kaliandara ditanam sesuai panduan yang diberikan sehingga dapat tumbuh baik di lahan milik peternak madu kelulut. Diharapkan dalam 2-3 tahun kedepan tanaman kaliandara dapat berbunga dan menjadi pakan yang dapat meningkatkan kulitas madu kelulut yang dikelola oleh kelompok peternak di Anjungan Melancar dan sekitarnya.
Aneka Olahan Sukun, Salak dan Daun Mangga Khas Kabupaten Bangkalan
Authors: Rachman Yudhi
Published: June 2020

Tulisan ini mencoba menampilkan upaya pemberdayaan melalui kegiatan KKN Mahasiswa Tematik Mandiri  Tahun 2018/2019  Universitas Trunojoyo Madura  di 3 Desa Ujung Barat Kabupaten Bangkalan.  Belajar dan berbagi dengan masyarakat desa yang sebagian besar adalah petani tadah hujan dengan memanfaatkan potensi sumber daya baik tanaman dan alam yang tersedia, berbagai kegiatan baik penyuluhan dengan berbagai tema dan pelatihan keterampilan pemasaran  produk unggulan sukun di Desa Sembilangan, buah salak dan bambu di Desa Kramat serta pengenalan inovasi produk alternatif seperti teh dan sirup berbahan daun mangga yang berlimpah dan tidak termanfaatkan di Desa Ujung Piring. Kesemuanya itu diharapkan mampu meningkatkan akses, kekuatan dan kemampuan bagi masyarakat desa pengolah produk untuk menjadi Desa Sejahtera.
Study the Best PenTest Algorithm for Blind SQL Injection Attacks
Authors: Nugroho Aldebaran Bayu , Mandala Satria
Published: June 2020

There are several types of SQL injection attacks. One of the most popular SQL Injection Attacks is Blind SQL. This attack is performed by exploiting a gap in the database server when executing query words. If the server responds to an invalid query, the attacker will then reverse the engineering part of the SQL query, which is obtained from the error message of the server. The process of generating a blind SQL injection attack is complicated. As a result, a Pentester often requires a long time to penetrate the database server. This research provides solutions to the problems above by developing the automation of a blind SQL injection attack. The method used in this research is to generate keywords, such as the database name and table name so that the attacker can retrieve information about the user name and password. This research also compares several search algorithms, such as linear search, binary search, and interpolation search for generating the keywords of the attack. Automation of the Blind SQL Injection was successfully developed, and the performance of the keywords generation for each algorithm was also successfully measured, i.e., 1.7852 seconds for Binary Search, 1.789 seconds for interpolation and 1.902 seconds for Linear Search.
Feasibility and design study of investment projects in metallurgy by the example of OJSC «BSW – Management Company of the Holding «BMC»
Authors: Karmanovich A. V. , Mozgov S. A.
Published: June 2020

The Republic of Belarus has defined requirements for project management, which are recommended for all participants involved in project activities, and provide for the organization of a systematic approach to the development and implementation of projects involving architectural and construction activities for the construction, reconstruction and restoration of buildings and structures. Comprehensive pre-investment study of the project reduces the risk of starting an inefficient project, because in the process of developing the investment justification: the costs associated with construction and installation work are defined more accurately; engineering-geological and geodetic surveys of the territory under construction and technical conclusions based on the results of the survey of the technical condition of buildings, internal and external engineering systems of buildings are taken into account; all principal decisions are made on the supply of engineering and transport infrastructure; the project’s impact on the environment is assessed, and public discussions are held on the environmental impact assessment report with the state environmental expertise; determine the possibility and options for adjusting the parameters of the investment project, the adopted technology and architectural and planning solutions in order to improve the effectiveness of the project, if the data obtained indicate insufficient profitability of the project.

This article describes the main provisions on the implementation of the pre-investment stage (development of pre-project documentation, business plan) of an investment project implemented in the metallurgical industry.
Uniform system for grouping of steels in welding manufacture by ISO/TR 15608
Authors: Bendik T. I. , Urbanovich N. I. , Nazarov D. A. , Figurin F. K.
Published: June 2020

Recommendations to assign steel grades most commonly used in industry and energy of the Republic of Belarus to a specific group and subgroup of the international standard ISO/TR 15608 are presented. These recommendations were made on the basis of a comparative analysis of the base metal chemical composition and its mechanical properties, given in the national and foreign standards for sheet and pipe metal rolling. Analysis of mechanical properties have been included conditions of thermal and thermomechanical treatment of the base metal. The information presented in the article can be useful for a wide range of welding specialists in documentation development for welding processes (WPS, WPQR), issuing welders attestation certificates (qualification test certificate) and other technological documentation.
Some particularities of microscopic investigation of non-metallic objects
Authors: Anisovich A. G. , Markevich M. I. , Malyshko A. N.
Published: June 2020

Thearticledealswith the comparative application of optical and raster microscopy for non-metallic objects and non-conducting surfaces. It is noted that this issue is not covered much in the special literature. There are practically no publications that compare and describe photos of the structure of materials obtained using fundamentally different microscopes, in particular, metallographic and raster. The causes of image distortion in a raster electron microscope in the study of dielectrics are considered. Comparative images of the oxidized surface, fabrics and natural leather obtained using raster and optical microscopy are presented. The advantages of optical microscopy in the study of non-conducting surfaces are shown.
CHANGES IN UTERINE CAPABILITY DUE TO INCREASED LITTER SIZE AT 7 WEEKS OF PREGNANCY IN KACANG GOAT
Authors: Arif Ridi , Satrija Fadjar , Winarto Adi , Boediono Arief , Manalu Wasmen
Published: June 2020

The purpose of this research was to study the changes in uterine support capability power due to increase of litter size in Kacang goat. In this study, 9 pregnant female Kacang goats were divided into 4 different groups based on litter size, namely 1, 2, 3, and 4. At 7 weeks of pregnancy, the experimental Kacang goats were sacrificed to observe the macro and micro parameters of the uterus. The results showed that the litter size had a quadratic relationship with micro parameters of uterus but it had a linear relationship with macro parameters of the uterus. The variables of uterine glands area, glands lumen area, and cytoplasmic area reached maximum condition at the litter size of 2.5. Litter size had a linear relationship with the volume, weight, and dimension of the uterus. It can be concluded that the optimal number of litter size in Kacang goat was two offsprings which was proven by the optimal function of the uterus to support fetal development.
THE PROFILE OF SUPEROXIDA DISMUTASE AND MALONDIALDEYDE LEVEL IN THE LIVER TISSUE OF HYPERCHOLESTEROLEMIC RATS TREATED WITH Holothuria nobilis POLYSACCHARIDE
Authors: Ulhusna Fitrah Asma , Winarto Adi , Wresdiyati Tutik
Published: June 2020

The aim of this research was to analyze the profile of superoxide dismutase (SOD) and malondialdehyde (MDA) on the liver tissue of hypercholesterolemic rats which were given Holothuria nobilis polysaccharides (HNP). A total of 15 male rats strain Sprague Dawley were divided into prevention and curative groups. Prevention group consisted of negative/non-hypercholesterolemic group (K-), positive/hypercholesterolemic group (K+), and hypercholesterolemic prevention group which were given 1% cholesterol diet and HNP at dose of 400 mg/kg bw (PCh). The treatments were given for 28 days. The curative group was consisted of the hypercholesterolemic group, which was given 1% cholesterol diet for 28 days, then followed by standard diet for 28 days (Ch), and the hypercholesterolemia curative group which was given 1% cholesterol diet for 28 days, then followed by 400 mg/kg bw HNP for 28 days (ChP). The antioxidant activity of HNP was analyzed by DPPH method. At the end of study the liver tissue was collected and analyzed for MDA, SOD while Cu,Zn-SOD was analyzed by immunohistochemical technique. The results showed that the antioxidant activity of HNP was weak. The MDA level (µg/g) in K-, K+, PCh, Ch, and ChP groups were 1.19±0.6; 3.37±0.79; 0.29±0.14; 9.11±0.72; and 3.14±1.06, respectively. The SOD activities (U/g) in K-, K+, PCh, Ch, and ChP groups were 2141.11±83.88; 1541±211.69; 2096.67±166.66; 1063.33±88.19; 1685.55±167.77, respectively. The immuno reactivity of Cu,Zn-SOD showed that HNP could increase Cu,Zn-SOD in the liver tissues of both groups. This study concluded that the HNP increased SOD activity, Cu,Zn-SOD antioxidant content, and decreased MDA levels in the liver tissues of hypercholesterolemic rats in both preventive and curative groups.
THE EFFECT OF COGON GRASS ROOT ETHANOL EXTRACT ON REPRODUCTIVE ORGAN AND EPIDIDYMAL SPERM QUALITY OF MOUSE WITH DIFFERENT AGES
Authors: Sudiman Jaqueline , Widyastuti Rini , Lubis Alkaustariyah , Hartady Tyagita , Syamsunarno Mas Rizky Anggun Adipurna , Sumarsono Sony Heru
Published: June 2020

This study aims to determine changes related to epididymal sperm parameters in mice given cogon grass root ethanol extract (CGREE). The experiment was carried out by dividing three groups of mice aged 4-week old (early pubertal), 8-week old (adult), and 24-week old (old) as control and treatment groups. The treatment groups were given 115 mg/kg body weight of CGREE for 14 days. The mice were sacrificed on day 15 to asses reproductive organ indexes and quality of the epididymal sperm. Index of epididymis and ductus deferens indices significantly reduced in the 4-week old treatment group compared to control (0.23 vs 0.33; 0.08 vs 0.16,  respectively), and vesical seminal significantly reduced in 8- week old treatment group compared to control (0.76  vs  0.68). The epididymal sperm quality significantly decreased in all treatment groups, but the sperm concentration in early pubertal group showed an increase. These results indicate that CGREE can enhance several semen parameters in prepubertal and adult mice but this effect is not apparent in old mice.
Mineral Level Status of Copper, Magnesium, and Iron in Local Goat Serum Related to Keeping Pattern System
Authors: Delima Mira
Published: June 2020

This research was conducted to find out the mineral level status of Cu, Mg, and Fe in blood serum of local goats which are reared with different methods. Blood serum was taken from 15 male and 15 female goats, 15-18 month old. The goats were divided into three groups which consist of 5 males and 5 females. Three methods of caging in which most commonly conducted by local people were selected as treatments, i.e. 1) Goats are caged only at night, while in daytime (around 10.00-12.00 WIB) they are discharged freely therefore they could foraging; 2) Goat are caged at night, while in daytime (around 10.00-18.00 WIB) they are bound with rope at which they could foraging around and, the rope would be removed several times in that particular daytime; 3) Goats are released freely all day long, but they are provided with kind of place as a cage, under the house or under the tree. Blood serum was taken from every unit sample. This research revealed that there was no significant different among methods of caging on the level rates of Cu, Mg, and Fe in local goat serum. The level rates of Cu, Mg, and Fe in goats serum that was found from the research were in normal range.
EFEK PAPARAN DEKOK BIJI PINANG (Areca catechu) TERHADAP MOTILITAS SPERMATOZOA TIKUS (Rattus norvegicus): UPAYA MENEMUKAN KANDIDAT ANTIFERTILITAS PRIA (The Effect of Betel Nut Extract (Areca catechu) on Mice Spermatozoa Motility (Rattus norvegicus: Effort to Find Out Man Antifertility Candidate)
Authors: Akmal Muslim
Published: June 2020

This research was conducted to prove the ability of betel nut extract (Areca catechu) in causingdegradation of sperm motility on rats (Rattus norvegicus) strain Wistar. This research used 2-3 monthsage, 200-250 g body weight of male white rats Rattus norvegicus strain Wistar. The rats were dividedinto 5 groups in equal number, 3 rats each group. They were a control group without treatment and 4treatment groups which were given different doses of betel nut extract for 7 days, i.e., 1, 2, 3, and 4 g/200g body weight respectively. The result showed that increasing doses of betel nut extract can result indegradation of sperm motility significantly (P0.05).Keywords: Areca catechu, Rattus norvegicus, sperm motility