bluuebunny/crossref_metadata_2025 huggingface dataset:
Tradisi Go Ge Cap Lak (Bakar Tongkang) Dalam Tinjauan Sosiologi Ekonomi Islam
Authors: Candra Kavita Lovia , Efrianti Esti , Purwanto Muhamad Aji
Published: August 2023

Introduction: Go Ge Cap Lak, according to the Chinese community, has the meaning of expressing gratitude to Kie Ong Ya (the god of the sea) who has given protection to their ancestors when sailing the ocean so that they can reach the Rokan Hilir region. In the course of its history, Go Ge Cap Lak in addition to having theological value also has a very thick anthropocentric value that makes the tradition as one of the religious tourism in the region. Not only the ethnic Chinese community benefited but also Muslims who lived in the local area. This tradition has become an annual event with a considerable economic impact. However, what if this tradition is seen in the study of Islamic economic sociology Research Methods: This research is included in the type of field research with qualitative descriptive data analysis methods. Primary data sources come from data mining in the field and supporting sites such as disbudpora, while secondary data sources come from previous research Results: The tradition has an economic impact on the surrounding Muslim community. This expediency is in line with the orientation of fulfilling life or in the language of religion in order to maintain life. Conclusion: Go Ge Cap Lak also has economic value. The Ministry of Tourism and Creative Industries includes Go Ge Cap Lak as one of the annual activities that are always held in Bagansiapiapi. This activity also made the economy of the Bagansiapiapi Muslim community rise and develop.
Seni Pegelaran Wayang dalam Perspektif Fikih dan Spiritualitas Seni Islam Seyyed Hossein Nasr
Authors: Masykur Muhammad Riduwan , Soleh Achmad Khudori
Published: August 2023

AbstractThe function of wayang in the context of ancient times was a means of worship and an intermediary in worshiping God. Whereas in Islam, it is not permissible to worship God by means of means or media, so this becomes a shirk to Allah, over time wayang changes its function, which is contrary to the past, and becomes more adaptive to the times. The purpose of writing this article is to discuss the art of wayang from the perspective of Islamic law or fiqh and in the study of the spirituality of Islamic art Seyyed Hossein Nasr. The writing of this article uses the library research method and literature sources that are in line with the discussion. This research resulted in findings that 1) wayang is an indigenous culture of the archipelago, which at first glance contradicts the views of Islamic jurisprudence and art by Seyyed Hossein Nasr 2) Wayang is an archipelago culture that has a great influence, in the perspective of fiqh, wayang performances are a form of Islamic art based on culture because of their use value today as art without associating partners with Allah., 3) From the perspective of Islamic art Seyyed Hossein Nasr Wayang is classified as a traditional Islamic art as its function is used in educational media through stories that are interesting and seem unique, the existence of wayang that can bring people to their goals Islamic art makes wayang used by walisongo as an effective preaching medium. AbstrakFungsi wayang dalam konteks zaman dahulu menjadi sarana ibadah dan perantara dalam menyembah Tuhan. Sedangkan dalam islam tidak diperkenankan menyembah Tuhan dengan menggunakan sarana atau media, sehingga hal tersebut menjadi syirik kepada Allah, seiring berjalannya waktu Wayang beralih fungsi yang bertolak belakang dengan zaman dahulu, dan menjadi lebih adaptif dengan perkembangan zaman. Tujuan penulisan artikel ini adalah untuk membahas seni rupa wayang dalam kacamata hukum islam atau fiqih dan dalam kajian spiritualitas seni islam Seyyed Hossein Nasr. Penulisan artikel ini menggunakan metode library research dan sumber literatur yang selaras dengan pembahasan. Penelitian ini menghasilkan temuan bahwa 1) wayang merupakan budaya asli Nusantara yang sekilas bertentengan dengan pandangan fiqih dan seni islam Seyyed Hossein Nasr 2) Wayang merupakan budaya Nusantara yang memiliki pengaruh yang besar, dalam perspektif fiqih, pagelaran Wayang merupakan salah satu bentuk seni islam berlandaskan budaya karena nilai kegunaannya pada zaman sekarang sebagai seni tanpa unsur menyekutukan Allah, 3) Dari perspektif seni islam Seyyed Hossein Nasr Wayang diklasifikasikan sebagai seni tradisional islam sebagaimana fungsinya yang digunakan dalam media pendidikan melalui cerita yang menarik dan terkesan unik, eksistensi wayang yang dapat membawa manusia kepada tujuan seni islam menjadikan wayang digunakan walisongo sebagai media berdakwah yang efektif.
Studi Economic Policy Uncertainty dan Pasar Keuangan terhadap Perkembangan Pasar Sukuk Indonesia
Authors: Alqurnia Ida , Musaiyaroh Ati , Wahyudi Amin , Alwa Moh. Abdul Aziz
Published: August 2023

AbstractSukuk as a form of sharia investment are starting to be in great demand by investors because they are considered to have a lower level of risk and better performance and stability compared to conventional investments. However, conditions of global uncertainty pose a threat to the development of the national sharia economy. The purpose of this study was to analyze the influence of macroeconomic dynamics and financial market conditions consisting of exchange rates, international liquidity, foreign debt, debt repayment rates, and global economic policy uncertainty on the development of Indonesian sukuk. The research methodology used in this study is the multiple linear regression method using the ordinary least squares method. The results of this study indicate that macroeconomic and financial variables have a significant impact on the development of the sukuk market in Indonesia. Meanwhile, the global economic policy uncertainty variable has an insignificant influence on the development of the sukuk market in Indonesia. Thus, there is a need for new policy alternatives to maintain overall economic fundamental stability and maintain sufficient liquidity in all sectors. This aims to maintain investor confidence and create a conducive environment for the development of Islamic economics and the sukuk market in Indonesia.  AbstrakSukuk sebagai salah satu bentuk investasi syariah mulai banyak diminati oleh investor karena dianggap memiliki tingkat resiko yang lebih rendah, memiliki kinerja dan stabilitas yang lebih baik dibandingkan dengan investasi konvensional. Namun, kondisi ketidakpastian global memberikan ancaman terhadap perkembangan ekonomi syariah nasional. Tujuan penelitian ini untuk menganalisis pengaruh dari dinamika ekonomi makro dan kondisi pasar keuangan yang terdiri dari nilai tukar, likuiditas internasional, utang luar negeri, dan tingkat pengembalian utang dan ketidakpastian kebijakan ekonomi global terhadap perkembangan sukuk Indonesia. Metode penelitian yang digunakan dalam penelitian ini yaitu metode regresi linear berganda dengan menggunakan metode Ordinary Least Square. Hasil dari penelitian ini menunjukkan bahwa variabel keuangan ekonomi makro memiliki pengaruh yang signifikan terhadap perkembangan pasar sukuk di Indonesia. Sedangkan variabel ketidakpastian kebijakan ekonomi global memiliki pengaruh yang tidak signifikan terhadap perkembangan pasar sukuk di Indonesia. Dengan demikian, perlu adanya alternatif kebijakan baru untuk tetap menjaga stabilitas fundamental ekonomi secara keseluruhan serta menjaga kecukupan likuiditas di segala sektor, hal ini bertujuan untuk menjaga kepercayaan investor serta membuat lingkungan yang kondusif bagi pengembangan pasar sukuk dan ekonomi islam di Indonesia.
Stereotip Perempuan dan Budaya Patriarkal Berlatar Islam dalam Novel Religi Best Seller Tahun 2000-2021
Authors: Hakim Lukman , Rahman Hasrul , Nurhana Robby Yudhi
Published: August 2023

AbstractThis research is a study of the image or stereotype of women in literary works, especially spiritual novels. This research interesting because many religious values in religious novels are considered counterfeminist and place women under male domination. The purpose of this research is to reveal stereotypes of women and patriarchal culture in the best selling spiritual novels for 2000-2021. This research was conducted by means of text or discourse analysis which investigates an event, either in the form of an act or writing in the best seller Spiritual Novels of 2000-2021 which is examined to obtain the exact facts (find the origins, causes, true causes, and so on). . The results of this study, namely: First. Women in the novel under study are still seen as people from the second class. There are many scenes showing women being discriminated against. Second, patriarchal culture still dominates stories in novels, especially religious novels. Many quotes show hegemony over women. Third, the socio-cultural background of the author influences the style of the novel's story. The setting of the novel is always related to the real life of the author. AbstrakPenelitian ini merupakan kajian terhadap citra atau stereotip perempuan dan budaya patriarkal berlatar islam dalam karya sastra khususnya novel Religi. Penelitian ini menjadi menarik karena nilai agama dalam novel religi banyak yang dianggap kontrafeminis dan menempatkan perempuan dalam dominasi laki laki.  Tujuan penelitian ini adalah untuk menyingkap stereotip perempuan dan budaya patriarki dalam novel Religi best seller tahun 2000-2021. Penelitian ini dilakukan dengan analisis teks atau wacana yang menyelidiki suatu peristiwa, baik berupa perbuatan atau tulisan dalam Novel Religi best seller tahun 2000-2021 yang diteliti untuk mendapatkan fakta-fakta yang tepat (menemukan asal-usul, sebab, penyebab sebenarnya, dan sebagainya). Hasil penelitian ini, yaitu: Pertama. Perempuan dalam novel yang diteliti  masih dipandang sebagai orang dari golongan kedua. Banyak adegan yang memperlihatkan perempuan mendapatkan diskriminasi. Kedua, budaya patriarki masih mendominasi cerita dalam novel khususnya novel religi. Banyak kutipan yang memperlihatkan hegemoni terhadap perempuan. Ketiga, latar sosial budaya pengarang berpengaruh terhadap corak cerita novel. Latar novel selalu berkaitan dengan kehidupan pengarang yang sebenarnya.
USTADZAH FASHION STYLE AS NONVERBAL COMMUNICATION AT THE AL-IMAN PUTRI PONDOK PESANTREN PONOROGO
Authors: Majidah Ismi Qomariyatul
Published: August 2023

Fashion Style is a form of nonverbal communication. The clothes a person wears can interpret themselves as well as show personality characteristics. The purpose of this study is to explain the purpose of using ustadzah Fashion Style at Al-Iman Putri Ponorogo Islamic Boarding School, and analyze the meaning of Fashion Style used by ustadzah as a means of Nonverbal Communication at Al-Iman Putri Ponorogo Islamic Boarding School.    The research method used is a qualitative approach with a descriptive method. Research data was collected by conducting interviews with informants, namely ustadzah Pondok Pesantren Al-Iman Putri who had qualifications as ustadzah who looked attractive and followed fashion trends.  The results showed that the use of fashion to communicate nonverbally about his identity. Everyone tries to show their best side and unique side of themselves through the fashion they wear. Ustadzah Pondok Pesantren Al-Iman Putri uses fashion style with the goal: easier to identify, convey a form of self-expression, and the purpose of beauty. Nonverbal Communication through fashion style ustadzah Pondok Pesantren Al-Iman Putri Ponorogo is considered effective because it produces communication results. And from the fashion style displayed, they try to convey their identity, character, class and group.
REVITALIZATION OF DA’WAH IN OVERCOMING OF MISSUNDERSTANDING AL-QURAN IN EARLY CHILDREN
Authors: Yusuf Mochamad Aris , Anam Hoirul , Supardi Supardi , Mushariawan Ilham
Published: August 2023

Da'wah activities in Islam are an obligation that must be carried out by every Muslim without exception. However, the perpetrators of da'wah are also required to understand the object of da'wah, this statement has been applied by mothers in completing the blindness of the Qur'an in early childhood. Where the success of da'wah built by mothers, is not because they are good at processing the words that are used in their da'wah activities, but because of the da'wah methods that are built according to the needs of the mad'u or object recipients of the da'wah material. So, in this article we want to know how the da'wah method is used by mothers. The purpose of this study is to dismantle the success of da'wah built by mothers. The method in this study uses qualitative research of the Phenomenological type. The findings in this article have shown that mothers can build an effective da'wah movement and are able to overcome Al-Qur'an literacy in young children at the Fathur Rahman Mosque by using three da'wah methods that were developed, namely: First, the motivational da'wah method. The two methods of preaching reward. The three methods of preaching are singing and sima'i.
Pengaruh Body Image Terhadap Kepercayaan Diri Remaja Putri
Authors: Mubarokah Tian Hayyin
Published: August 2023

Body image is a multidimensional, subjective, and dynamic concept that includes one's perception. Thoughts, and feelings about his body. Body image is not limited to a person's aesthetic characteristics, but also considers his health condition, skills, and sexuality. A person will be confident when the person realizes his ideal body shape and the person is satisfied to see his body shape, then the body image that is formed is also positive. Conversely, if someone views his body as not ideal, such as his face is less attractive, which is formed into a negative and it can be said that the person is not confident. The purpose of this study was to describe the effect of body image on the self-confidence of teenage girls in grade xi at SMAN 1 Geger Madiun. This study uses a quantitative approach to the type of correlational research. The data collection technique in this study used a questionnaire technique. Meanwhile, to analyze the data in this study using a simple linear regression formula. Based on the data analysis, it was found that there was a significant influence between body image on the self-confidence of the eleventh grade girls at SMAN 1 Geger Madiun. This is known from the results of calculations using SPSS, namely Fcount (19.965) > Ftable (1.97) so that Ho is rejected. While the magnitude of the effect is 35.7%. The effect of body image on the self-confidence of adolescent girls in class XI at SMAN 1 Geger Madiun is in the medium (good) category. This is obtained from the results of student questionnaires with details of 64.3% with a frequency of 64 out of 184 respondents. The medium category in this study was considered good because the effect of body image on the self-confidence of the eleventh grade girls at SMAN 1 Geger Madiun was balanced.keywords : Body Image, Confidence
Bahasa Kasar (Abussive Language) Dan Dampaknya Bagi Perkembangan Perilaku Anak
Authors: Armita Dina
Published: August 2023

Abstrak Masa pertumbuhan anak sesusia SD akan banyak sekali menemukan hal-hal baru dan juga menarik untuk ditiru, apalagi pada umur segitu anak-anak masih dalam masa suka meniru orang yang berada di sekitarnya. Fenomena yang saat ini terjadi di banyak tempat tinggal atau lingkungan masyarakat ternyata sangat banyak sekali anak-anak yang sangat suka berkata kasar. Oleh sebab itu, diperlukan segenap usaha untuk menghilangkan atau mengurangi bahasa kasar tersebut agar tidak di tirukan lagi oleh anak yang lainnya sehingga mampu menciptakan generasi yang baik untuk kedepannya. Tujuan dalam penelitian ini adalah untuk Mendeskripsikan apa saja faktor yang mempengaruhi kebiasaan berkata kasar. Upaya penanganan kepada anak yang berkata kasar dan Dampak dari perilaku anak yang sering berkata kasar. Metode yang digunakan adalah metode penelitian kualitatif dengan menggunakan tipe penelitian studi kasus. Hasil dari penelitian ini adalah: Faktor yang mempengaruhi abussive language pada perkembangan perilaku anak adalah faktor keluarga, lingkungan, teman bermainnya, dan media sosial. Upaya penanganan terhadap kebiasaan abussive language pada anak yaitu di peringatkan secara halus, ada juga yang langsung di tegur dengan keras. Dampak bagi perkembangan perilaku anak yang melakukan abussive language adalah sulit untuk menemukan keunggulan atau talenta dalam diri sendiri, dikucilkan orang sekitar, sulit untuk mencapai kesuksesan.Kata Kunci : Abussive Language, Perkembangan Perilaku Anak, Dampak.
Implementasi Pembelajaran Musik Dan Gerak Pada Guru PAUD Di Kecamatan Parongpong, Kabupaten Bandung Barat
Authors: Kurniawati Leli , Putri Riva Ananda , Afifah Anindya Alya , Kamil Siti Wardah Khofifah
Published: August 2023

This study aims to find out how teachers implement music and movement learning in early childhood education in Parongpong District, West Bandung Regency, West Java. With a case study methodology, a qualitative research design was applied. Then observation and literature research are utilized as data collection methods. Descriptive qualitative analysis is the method of data analysis that is employed. The study's findings demonstrate that teachers have effectively incorporated music and movement into early childhood learning through appropriate stimulus, variety, expression, tempo, and enthusiasm in line with their pedagogical, personal, social, and professional competence as teachers of early childhood education.
Is there a Subnational Resource Curse? Evidence from Households in the Niger Delta Region of Nigeria
Authors: Animashaun Jubril , Emediegwu Lotanna
Published: August 2023

Previous evidence suggests that mining-based extractive sectors have a net positive effect on local economies, further improving the local population’s living standards. In contrast to artisanal mining, we argue that hydrocarbon-based industries can have ambiguous implications on demand in sectors that will enhance local welfare. Using annual household data from the Niger Delta between 2010 and 2016, we utilize a combination of fixed effects and difference-in-differences, triple–differences (DDD), and treatment boundaries in oil production and households’ locations to produce unbiased estimates. Estimating at a subnational level allows us to exploit variation within a country, control for more potential sources of estimation bias, and measure the impact of compositional changes on households’ expenditures. We find that costs of living are higher by proximity to oil fields, but the mechanism is via preferences for education. We find inconclusive evidence on other welfare indicators; limited employment opportunities and rent-seeking environment may explain the weak backward linkages and potential positive spillovers. JEL Codes: O13, O18, Q32, J24, I2, R20
Privacy Preserving Mechanism using No-regret learning in Cyber-Physical Systems
Authors: Yogi Manas Kumar , N Chakravarthy A S
Published: August 2023

Modern cyber-physical systems have become the backbone of Indus- try 4.0.With the increasing popularity and usage of such systems the privacy aspect is also becoming a pertinent issue because the sensitive user data drives the whole CPS ecosystem .In this paper we have modeled the privacy preserva- tion problem as a game in which by application of no-regret learning mecha- nism, we intend to minimize the privacy loss. Furthermore the experimental re- sults indicate the promising nature of the performance of the technique and we have also addressed the challenges faced by the proposed mechanism. In future we want to provide a case study for the applicability of our novel technique in a controlled CPS setup.
Immortalized Mesenchymal Stromal Cells Overexpressing Alpha-1 Antitrypsin Protect Acinar Cells from Apoptotic and Ferroptotic Cell Death
Authors: Shoeibi Sara , Green Erica , Wei Hua , Gou Wenyu , Strange Charlie , Wang Hongjun
Published: August 2023

Chronic pancreatitis (CP) is a progressive inflammatory disorder that impairs endocrine and exocrine function. Our previous work suggests that mesenchymal stem/stromal cells (MSCs) and MSCs overexpressing alpha-1 antitrypsin (AAT-MSCs) could be therapeutic tools for CP treatment in mouse models. However, primary MSCs have a predisposition to undergo senescence during culture expansion which limits their therapeutic applications. Here we generated and characterized immortalized human MSCs (iMSCs) and AAT-MSCs (iAAT-MSCs) and tested their protective effect on 2,4,6-Trinitrobenzenesulfonic acid (TNBS) -induced acinar cell death in an in vitro cell culture system. Primary MSCs were immortalized by transduction with simian virus 40 large T antigen (SV40LT), and the resulting iMSC and iAAT-MSC lines were analyzed for proliferation, senescence, phenotype, and multi-differentiation potential. Subsequently, the impact of these cells on TNBS-induced cell death was measured and compared. Both apoptosis and ferroptosis pathways were investigated by assessing changes of critical factors before and after cell treatment. Coculture of iMSCs and iAAT-MSCs with acinar cell lines inhibited early apoptosis induced by TNBS, reduced ER stress, and reversed TNBS-induced protein reduction at tight junctions. Additionally, iMSCs and iAAT-MSCs exerted such protection by regulating mitochondrial respiration, ATP content, and ROS production in TNBS-induced acinar cells. Furthermore, iMSCs and iAAT-MSCs ameliorated ferroptosis by regulating the ferritin heavy chain 1 (FTH1)/protein disulfide isomerase (PDI)/glutathione peroxide 4 (GPX4) signaling pathways and by modulating ROS function and iron generation in acinar cells. These findings identified ferroptosis as one of the mechanisms that leads to TNBS-induced cell death and offer mechanistic insights relevant to using stem cell therapy for the treatment of CP.
Agricultural land use suitability analysis using GIS and AHP technique in Baramulla district of the Kashmir valley, India
Authors: Khan Ruyida Mushtaq , Ahmed Pervez
Published: August 2023

Land suitability studies are necessary for reducing human impact on natural resources and figuring out the best way to use a piece of land. In the Baramulla district of the Kashmir valley, an effort has been made in this study to pinpoint a suitable land area for agriculture suitability. Because of this, choosing appropriate locations for agriculture suitability while preserving ecological balance has become a necessary component of sustainable land use planning and agriculture. We assess the land suitability for agriculture in Baramulla, India, using fundamental characteristics such as slope, elevation, temperature, rainfall, LULC, physical and chemical qualities of the soil, and utilised weighted multicriteria evaluation (MCE) technique in a GIS context. Utilising the literature that was accessible and interviews with regional experts, the AHP approach was used to score the criteria. Through weighted overlay analysis, a map of the research area's agricultural suitability was created by incorporating several criteria. According to a map showing the suitability of the land for agriculture in the study region, 16.59% of the land was extremely suitable, 28.16% of the land was moderately suitable, 40.29% of the land was marginally acceptable, and 14.96% of the land was unsuitable. The results have also been thoroughly examined using Google Earth images, in comparison with Sentinel-2b LULC output, in order to increase the trustworthiness of the data. Farmers, regional planners, and the government can utilise the research study's findings to guide their decisions regarding prospective agriculture areas in the region and the strategies that will provide a sustainable agriculture land management strategy.
Exoskeleton For Specially Abled
Authors: Wani Vaibhav Anil , Shaikh Mohd Shahed , Shewale Yash S , Nair Sreelakshmi M
Published: August 2023

This is a paper about a wearable exoskeleton that addresses the lack of assistive devices for people with walking difficulties. The research revolves around the major problem in which the inpatient suffer for their dependency on a caretaker for basic tasks such as toiletries and fetching water or food or even for basic cores for themselves. People with disabilities suffer from many social and mental pressures due to exclusion from society just for being different from normal human beings. Hence, the usage and purpose of robotic technology trims down this segregation and promote vocational incorporation.
Assessment of the level of Heavy Metals in Ecosystem around Quarry site in Ogun State, Nigeria
Authors: Ogunmade Taiwo B. , Adeyemi Olufemi O. , Osobamiro Temitope M. , Olubusoye Boluwatife S. , Alabi Oluwatobi
Published: August 2023

This study investigated the anthropogenic impacts of quarrying activities on the ecosystem. Soil, rock, water, and plant samples were collected at varying distances around a quarry site located in Ijebu North local government area of Ogun State, Nigeria. The physicochemical properties were determined using standard methods, and metal quantification was done using Inductively Coupled Optical Emission Spectrometry (ICP-OES). The results of physicochemical properties of the sampled soil include: pH (7.20–8.74), bulk density (0.922–1.198 g/cm³), and moisture content (26.3–34.1%). Turbidity is 56.3 higher than the WHO standard, while alkalinity is 144. The physicochemical properties of the water samples all fall within the permissible limits set by the WHO except for alkalinity, turbidity, hardness, suspended solids, and COD. The results of metal analysis (mg/kg) are as follows: ≤9.94, ≤ 3961.77, ≤ 11.07, ≤ 244.03, ≤ 111.77, ≤ 251.19, ≤ 262.84, ≤ 101.23, ≤ 3094.87, ≤ 2816.07, ≤ 235.78, ≤ 182.72 for Ag, Al, As, B, Ba, Cd, Co, Cr, Cu, Fe, Mn, Ni, and Pb, respectively, in all the environmental samples. High levels above the WHO permissible standard of toxic metals under study were found in rock samples, and these are statistically similar to the levels recorded in soil samples close to the quarry site. Additionally, high levels of Al, Cd, Cr, Cu, Fe, and Mn above the WHO limit were recorded in plant and water samples close to the quarry site. Quarry activities in the study site have a negative impact on the soil, plant, and water body around the site, and this needs to be checked on time before it degenerates into an environmental catastrophe.
The introduction of video-enabled directly observed therapy (video-DOT) for patients with drug-resistant TB disease in Eswatini amid the COVID-19 pandemic – a retrospective cohort study
Authors: Kerschberger Bernhard , Daka Michelle , Shongwe Bhekiwe , Dlamini Themba , Ngwenya Siphiwe , Danbakli Clara , Mamba Bheki , Nxumalo Bongekile , Sibanda Joyce , Dube Sisi , Dlam Lindiwe Mdluli , Mabhena Edwin , Mukooza Esther , Crumley Iona , Ciglenecki Iza , Vambe Debrah
Published: August 2023

Background
Video-enabled directly observed therapy (video-DOT) has been proposed as an additional option for treatment provision besides in-person DOT for patients with drug-resistant TB (DRTB) disease. However, evidence and implementation experience mainly originate from well-resourced contexts. This study describes the operationalization of video-DOT in a low-resourced setting in Eswatini facing a high burden of HIV and TB amid the emergence of the COVID-19 pandemic. Methods
This is a retrospectively established cohort of patients receiving DRTB treatment during the implementation of video-DOT in Shiselweni from May 2020 to March 2022. We described intervention uptake (vs in-person DOT) and assessed unfavorable DRTB treatment outcome (death, loss to care) using Kaplan-Meier statistics and multivariable Cox-regression models. Video-related statistics were described with frequencies and medians. We calculated the fraction of expected doses observed (FEDO) under video-DOT and assessed associations with missed video uploads using multivariable Poisson regression analysis.
Results
Of 71 DRTB patients eligible for video-DOT, the median age was 39 (IQR 30–54) years, 31.0% (n=22) were women, 67.1% (n=47/70) were HIV-positive, and 42.3% (n=30) were already receiving DRTB treatment when video-DOT became available. About half of the patients (n=37; 52.1%) chose video-DOT, mostly during the time when COVID-19 appeared in Eswatini. Video-DOT initiations were lower in new DRTB patients (aHR 0.24, 95% CI 0.12–0.48) and those aged ≥60 years (aHR 0.27, 95% CI 0.08–0.89). Overall, 20,634 videos were uploaded with a median number of 553 (IQR 309–748) videos per patient and a median FEDO of 92% (IQR 84–97%). Patients aged ≥60 years were less likely to miss video uploads (aIRR 0.07, 95% CI 0.01–0.51). The cumulative Kaplan-Meier estimate of an unfavorable treatment outcome among all patients was 0.08 (95% CI 0.03–0.19), with no differences detected by DOT approach and other baseline factors in multivariable analysis.
Conclusions
Implementing video-DOT for monitoring of DRTB care provision amid the intersection of the HIV and COVID-19 pandemics seemed feasible. Digital health technologies provide additional options for patients to choose their preferred way to support treatment taking, thus possibly increasing patient-centered health care while sustaining favorable treatment outcomes.
Evaluation of tornado loads on double-sloped roofs at various ground roughness and positions by numerical Ward-type tornado simulation
Authors: Yuan Zhongya , Wang Xueyan , Jia Yanzhen , Cao Wenlong , Yang Jian , An Jianhui
Published: August 2023

The effect of various slope angles, ground roughness and positions on tornado loading characteristics of double-sloped roof is identified through Ward-type tornado numerical simulation. Tornado fields under multiple operating conditions are established through a numerical Ward-type tornado generation apparatus and the reliability is verified by comparing simulation results with experimental data. A comparison of wind pressure distribution for double-sloped roofs with four different angles is used to determine the most unfavourable roof conditions for a tornado field. The wind pressure characteristics of double-sloped roofs at different locations in a tornado field is examined by comparing the wind pressure coefficients at five different locations on smooth and rough ground. Calculations of wind pressure coefficients for five ground roughness are carried out to identify the effect of different ground roughness on wind pressure distribution in roofs. Vortex volumes at different locations are calculated and analyzed to further verify the relationship between the wind pressure characteristics at different locations. This study sheds light on tornado loads on double-sloped roofs at various ground roughness and positions, and helps to clarify the mechanical properties, unfavourable locations and wind resistance design of double-sloped roofs under tornado action.
Bionanocomposite MIL-100(Fe)/Cellulose as a high-performance adsorbent for adsorption of methylene blue
Authors: Abbasi Shahla , Nezafat Zahra , Javanshir Shahrzad , Aghabarari Behzad
Published: August 2023

Water refining treatment consisted to eliminate organic matter and improve the organoleptic qualities of the water (flavor, smell, clarity). There are different methods for removal of pollutants which among them, the adsorption process has been expanded due to its easiness and high efficiency. The development of innovative porous materials is therefore of primary importance for the treatment of effluents. Dyes are important source of pollution once discharged into the environment. World production of dyes is estimated at more than 800,000 t•yr− 1. The purpose of this research falls within the scope of the choice of an effective, local and inexpensive adsorbent to remove dyes from waste water. Adsorptive elimination of dyes by commonly accessible adsorbents is inefficient. The metal organic frameworks (MOFs) are important class of porous materials offering exceptional properties as adsorbents by improving separation efficiency compared to existing commercial adsorbents. However, its powder form limits its applications. One way to overcome this problem is to trap them in a flexible matrix to form a hierarchical porous composite. Therefore, in this work, we prepared MIL-100 (Fe) embedded in cellulose matrix named MIL-100(Fe)/Cell, and used it as an adsorbent of methylene blue (MB) dye. Adsorption was studied as a function of contact time, adsorbent mass and pollutant load (concentration), and pH, and the effect of each of them on absorption efficiency was optimized. MIL-100(Fe)/Cell was capable to remove 98.94% of MB dye with an initial concentration of 150 mg/L within 10 minutes. The obtained maximum adsorption capacity was 384.615 mg/g. The adsorption isotherm and kinetic were consistent with the Langmuir and pseudo-second order models. The mechanism of MB adsorption proceeds through п-п and electrostatic interactions.
Outcomes with hybrid catheter-directed therapy compared with aspiration thrombectomy for patients with intermediate-high risk pulmonary embolism
Authors: Sławek-Szmyt Sylwia , Araszkiewicz Aleksander , Jankiewicz Stanisław , Grygier Marek , Mularek-Kubzdela Tatiana , Lesiak Maciej
Published: August 2023

Purpose
Intermediate-high-risk pulmonary embolism (IHR PE) is a challenging form of embolism obstruction that causes right ventricular dysfunction. The optimal management of IHR PE has not been established. This single-center prospective, observational study aimed to evaluate the efficacy and safety of hybrid therapy (CDT)- catheter-directed mechanical aspiration thrombectomy (CDMT) in comparison to CDMT supplemented with catheter-directed thrombolysis (hybrid CDT) for IHR PE.
Methods
A propensity score based on Pulmonary Embolism Severity Index class and Miller Obstruction Index (MOI) was calculated, and 21 hybrid CDT cases (mean age 54.8 (14.7) years, 9/21 women) were matched with 21 CDMT cases (mean age 58.8 [14.9] years, 13/21 women). The baseline demographics and clinical and treatment characteristics were analyzed.
Results
No significant differences were detected regarding baseline demographics and PE severity parameters. Hybrid CDT demonstrated a higher reduction in mean pulmonary artery pressure (mPAP) (hybrid CDT: median mPAP reduction 8 mmHg [IQR: 6–10 mmHg] vs CDMT: median mPAP reduction 6 mmHg [IQR: 4–7 mmHg; P = 0.019), MOI score (hybrid CDT: median change − 5 points [IQR:5–6 points] vs CDMT median change − 3 points [IQR:3–5 points]; P = 0.019), and median RV: Left ventricular ratio (hybrid CDT: median change 0.4 [IQR:0.3–0.45] vs CDMT median change 0.26 [IQR:0.2–0.4]); P = 0.007). No major bleeding was observed. Both the hybrid CDT and CDMT alone treatments are safe and effective in managing IHR PE.
Conclusions
Hybrid CDT is a promising technique for the management of IHR PE with insufficient thrombus load reduction by CDMT.
Trial registration number:
NCT0447356 – registration date 16 July 2020
Mindflow in crisis: the mediating role of psychological capital and coping competence between mindfulness and flow during COVID-19.
Authors: Rahnama Nargess , Malekzadeh Gholamreza , Moshtari Mohammad
Published: August 2023

Background
The present study aims to investigate whether and how mindfulness leads to the flow experience in high-pressure situations during the coronavirus pandemic peak, especially in high-risk, challenging contexts such as emergencies. therefore, the authors aim to expand existing knowledge about experiencing flow at work, specifically in the crisis context of the COVID-19 period, when challenges convert to hindrance demands. Before examining the possible processes and mechanisms in this relationship, we examined the mediating role of two variables: psychological capital and coping competence.
Method
The statistical population of this study consists of all employees of emergency centers in Mashhad, Iran; there were 550 at the time of the study. Using a simple random sampling method and the Morgan table, a sample of 220 people was considered. A structural equation model, AMOS, and SPSS software were used to analyze the collected data.
Result
The results emphasize that among employees who experienced mindfulness, an optimal experience did not necessarily occur, specifically in those situations in which challenge stressors become hindrance stressors. Although the association of mindfulness and coping competence was verified, its association with flow through coping competence was rejected. It is verified that mindfulness would be associated with flow through psychological capital.
Conclusion
The study extends our understanding of occurring flow at high-risk work environments in which challenges are not motivational. The authors studied the experience of flow in a work context with challenges that appear in the form of hindrance demands, different from the previous ones that have studied flow experience in challenging and motivating contexts such as sports contexts, including mountain climbing, surfing, and similar cases. In addition, there was no consensus in different past studies about associating mindfulness with flow experience. Therefore, in this case, further study had been left to future studies. Moreover, the process of this relationship through the mediating role of psychological capital and coping competence has not been investigated in previous studies.
A bridge between infertility and anxiety: a novel role for genes
Authors: Bausyte Raminta , Mazeikiene Brigita Vaigauskaite - , Skliute Giedre , Valatkaite Elvina , Sabaityte Evelina , Kazenaite Edita , Ramasauskaite Diana , Navakauskiene Ruta
Published: August 2023

Background. Infertility can negatively affect mental health. Conversely, it is also hypothesized that psychological imbalance may exert a damaging influence on reproductive function. Unfortunately, until now it has been difficult to objectively explain these relations. Certain researchers suggest that genetic and epigenetic mechanisms could be factors. The aim of this study was to investigate the connection between infertility, anxiety and (or) depression by examining underlying genetics, so we can formulate future perspectives.
Methods. The present study was conducted in few stages: (a) psychological assessment of females undergoing assisted reproductive technology (ART) procedure due to couple infertility, using the Hospital Anxiety and Depression Scale (HADS); (b) collection of endometrial samples before ART cycle from study participants; (c) isolation and cultivation of human endometrial-derived mesenchymal stromal cells (EnSCs); (d) analysis of 26 EnSCs’ genes by the reverse transcription-quantitative polymerase chain reaction (RT-qPCR): cell cycle regulation related (SLC39A1, RBM6, BLCAP, GATAD2B, RNF123, RECQL4), immune response related (AFF3, CD58, TNFSF4), signal transduction related (ESR1, CRTC2, CXCL8, PPP1R16A, NDN, GRB10, HTR2A, RB1, NR3C1, AXL), cell differentiation related (PAX8AS1, H19, EFNA5, IGF2), secretion related genes (MON1A, CYR61) and embryogenesis related genes (TFPI2); (e) statistical analysis; (f) summarization.
Results. We investigated 32 females. 12 females expressed considerable symptoms of anxiety and 1 female showed symptoms of depression. 19 females conceived after ART procedures. Genetic analysis showed tendentious alterations in certain cell cycle regulation and transcription/translation, immune response, signal transduction, cell differentiation, secretion and embryogenesis process related gene expression according to female expression of anxiety. Moreover, it was observed that certain mechanisms could adversely affect pregnancy outcome after ART cycle or at least reflect it.
Conclusions. It is known that infertility can have a harmful impact on a person’s psychology. However, a perception can be made that some tendencies such as anxiety may affect fertility even through the gene profile. The results we obtained encourage a deeper exploration of the relationship between fertility disorders, psychology and genes, as it does seem that qualified and timely psychological assessment, counselling and support could be one of the keys to raising pregnancy rates among infertile couples.
Mesenchymal Stem Cells Lose the Senescent Phenotype Under 3D Cultivation
Authors: Krasnova Olga , Kovaleva Anastasiia , Saveleva Arina , Kulakova Karina , Bystrova Olga , Martynova Marina , Domnina Alisa , Neganova Irina
Published: August 2023

Background Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of thein vivomicroenvironment, which is essential for obtaining more relevant results. The application of 3D cell culture techniques in regenerative medicine, particularly in mesenchymal stem cell (MSC)-based research, has been extensively studied. Many of these studies focus on the enhanced paracrine activity of MSCs cultured in 3D environments. However, few focus on the cellular processes that occur during 3D cultivation. Methods In this study, we studied the changes occurring within 3D-cultured MSCs (3D-MSCs). Specifically, we examined the expression of numerous senescent-associated markers, the actin cytoskeleton structure, the architecture of the Golgi apparatus and the localization of mTOR, one of the main positive regulators of replicative senescence. In addition, we assessed whether the selective elimination of senescent cells occurs upon 3D culturing by using cell sorting based on autofluorescence. Results Our findings indicate that 3D-MSCs were able to overcome replicative senescence. We discovered changes in actin cytoskeleton structure, Golgi apparatus architecture and revealed that 3D cultivation leads to the nuclear localization of mTOR, resulting in a decrease in its active cytoplasmic form. Furthermore, we confirmed that 3D cell culture facilitates the rejuvenation of senescent cells rather than their elimination from the bulk population. Conclusion These novel insights into the biology of 3D-MSCs can be applied to research in regenerative medicine to overcome replicative senescence and MSC heterogeneity as they often pose significant concerns regarding safety and effectiveness for therapeutic purposes.
Serum metabolome analysis in hyperthyroid cats before and after radioactive iodine therapy
Authors: Bechtold Molly A. , Lin Yimei , Miller Meredith L. , Prieto Jennifer M. , Frederick Carol E. , Bennett Lucinda L. , Peterson Mark E. , Simpson Kenneth W. , Loftus John P.
Published: August 2023

Hyperthyroidism is the most common feline endocrinopathy. In hyperthyroid humans, untargeted metabolomic analysis identified persistent metabolic derangements despite achieving a euthyroid state. Therefore, we sought to define the metabolome of hyperthyroid cats and identify ongoing metabolic changes after treatment. We prospectively compared privately-owned hyperthyroid cats (n = 7) admitted for radioactive iodine (I-131) treatment and euthyroid privately-owned control (CON) cats (n = 12). Serum samples were collected before (T0), 1-month (T1), and three months after (T3) I-131 therapy for untargeted metabolomic analysis by MS/MS. Hyperthyroid cats (T0) had a distinct metabolic signature with 277 significantly different metabolites than controls (70 increased, 207 decreased). After treatment, 66 (T1 vs. CON) and 64 (T3 vs. CON) metabolite differences persisted. Clustering and data reduction analysis revealed separate clustering of hyperthyroid (T0) and CON cats with intermediate phenotypes after treatment (T1 & T3). Mevalonate/mevalonolactone and creatine phosphate were candidate biomarkers with excellent discrimination between hyperthyroid and healthy cats. We found several metabolic derangements (e.g., decreased carnitine and a-tocopherol) do not entirely resolve after achieving a euthyroid state after treating hyperthyroid cats with I-131. Further investigation is warranted to determine diagnostic and therapeutic implications for candidate biomarkers and persistent metabolic abnormalities.
Federated Learning: Healthcare, Security, Challenges, and Threats
Authors: N Sumanth , Heggere Shalini B , E Prathiksha , Shetty Chintan Ashok , H Nikhitha H R , C Soundarya B
Published: August 2023

Over the last four years, machine learning has undergone a significant shift due to concerns over privacy and the desire for deep learning. New methods of implementing machine learning, such as federated learning (FL), are replacing centralized systems and on-site analysis. FL is a decentralized approach that safeguards privacy by storing raw data on devices and using local machine learning to reduce communication costs. A central server collects and distributes shared models and knowledge among participants. Before delving into FL, this essay compares and contrasts various ML-based deployment strategies.
This paper presents a unique classification of FL challenges and research areas, unlike previous analyses in the field. It is based on a thorough analysis of key technological roadblocks and current activities, and covers intricate subjects, contributions, and trends in the literature. The taxonomies encompass fundamental system models and designs, application domains, privacy and security, and resource management. Additionally, this paper discusses significant difficulties.
Change of Direction and Linear Speed Relation to Functional Ability and Joint Mobility in Polish Women’s Volleyball and Basketball 3x3 National Teams
Authors: Czyżnielewska Zuzanna , Yagin Fatma Hilal , Gabryś Tomasz , Cepicka Ladislav
Published: August 2023

The purpose of this study was to determine the relationship between sprint, COD, CODD and functional status in polish women’s national teams: volleyball and basketball 3x3. A total of 23 athletes: 12 volleyball players (age:18 ± 0years; body height:183 ± 7cm; body weight:70 ± 8kg) and 11 basketball players (age:26 ± 4 years; body height:180 ± 6cm; body weight:73 ± 10kg) participated in the study. Athletes were tested for the following measures: FMS test, Y-Balance test, joints range of motion measurements, maximal sprint test (14m) and modified COD test (14m). COD deficit was calculated by subtracting COD speed time from sprint speed time. A value of p < 0.05 was considered statistically significant. There was no significant correlation between sprint and CODD results in basketball team. In volleyball team there was a positive and significant correlation between COD, sprint and CODD. There was a negative and significant correlation between Y-Balance scores and sprint test results in the basketball team. Basketball team had a positive significant correlation between hip rotations and COD results. Volleyball team results of the upper back rotations and sprint test were found to have a negative significant correlation. There was a negative significant correlation between shoulder movements and COD and CODD results in volleyball team.
Chatter Stability Analysis and Prediction for Elliptical Ultrasonic Vibration-assisted Milling Process
Authors: Li Zhongqun , Yang Shangzhen , Liu Qiang , Liu Hong , Liu Yang
Published: August 2023

Elliptical ultrasonic vibration-assisted milling (EUVAM) introduces ultrasonic frequency vibration into conventional milling (CM) to achieve high-frequency intermittent milling. It has broad application prospects in processing of difficult-to-cut materials such as titanium alloys, superalloys, carbon fiber reinforced plastic (CFRP), and hard and brittle materials. This study focuses on the development of a dynamic model for EUVAM that considers regenerative effects and analyzes the interaction between the cutting edge and the workpiece in both radial and tangential directions, and the dynamic chip thickness is derived based on this model. To solve the model, a Runge-Kuta based fully discrete method (RKFDM) is employed. This numerical method accurately predicts the stability of the EUVAM process under specified cutting conditions. In addition, a bisection algorithm is utilized to construct the stability lobe diagram of EUVAM, enhancing the computational efficiency of the process. Stability tests are conducted to validate the proposed stability model and solution method for EUVAM. The results of these tests confirm the accuracy and reliability of the approach presented in this paper. This study provides valuable insights and a practical framework for implementing EUVAM in the processing of difficult-to-cut materials, offering improved machining performance in various industrial applications.