bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding Private Equity Funds: A Guide to Private Equity Research in Accounting
Authors: Borysoff Maria Nykyforovych , Mason Paul , Utke Steven
Published: August 2023

Private equity (PE) funds are increasingly important to the economy and now serve as the primary vehicle for raising new capital. However, a limited understanding of the unique PE fund setting among accounting academics inhibits accounting research in this area. In this paper, we first describe the PE fund setting and explain how fundamental differences between PE and previously studied settings make it difficult to infer PE fund behavior from research performed using other settings. We then discuss how PE funds provide researchers with the ability to explore fundamental questions related to agency costs, governance, compensation, disclosure, and fair value accounting. Finally, we provide guidance on PE data sources available for use in future research. Because of the volume of economic activity currently funneled through PE and the unique aspects of the PE setting, it is important for researchers to explore when, why, and how accounting matters for PE funds.

Data Availability: Data used in this study are available from the public sources identified in the text.

JEL Classifications: G1; G14; G30; M4; M41.
Beneficial Effects of Control-IQ Automated Insulin Delivery in Basal-Bolus and Basal-Only Insulin Users With Type 2 Diabetes
Authors: J. Levy Carol , Raghinaru Dan , C. Kudva Yogish , Pandit Keta , Blevins Thomas , Casaubon Luis , Desjardins Donna , M. Levister Camilla , O’Malley Grenye , Reid Corey , Lum John , Kollman Craig , W. Beck Roy
Published: August 2023

The t:slim X2 insulin pump with Control-IQ technology (Control-IQ) advanced hybrid closed-loop automated insulin delivery system was evaluated in this prospective single-arm trial. Thirty adults with type 2 diabetes using the Control-IQ system showed substantial glycemic improvement with no increase in hypoglycemia. Mean time in range (70–180 mg/dL) improved 15%, representing an increase of 3.6 hours/day, and mean glucose decreased by 22 mg/dL.
Characterization of elastase-like enzymes in various blistering diseases
Authors: Oikarinen A , Kiistala U , Uitto J.
Published: August 2023

Blister fluid samples were collected from suction induced control blisters and from spontaneous blisters from various blistering diseases for the measurement of elastase-like enzyme activities using synthetic succinyl-L-(alanyl)3-paranitroanilide (SAPNA) and alanyl paranitroanilide (ala-PNA) as the substrates. The blister fluids derived from bullous pemphigoid, pyoderma or epidermolysis bullosa dystroficans lesions contained higher levels of elastase-like enzyme activities than burn blisters or fresh suction blisters. The gel filtration studies using Sepharose CL-4B chromatography revealed two major peaks of SAPNA hydrolysing enzyme activity in burn blister and in bullous pemphigoid blister. The first peak eluted in void volume, and the second peak had an apparent molecular weight of 2.5 X 10(5) daltons. The results indicate that various proteinases are present in blisters fluids and that they may participate in the blister formation by degrading structural components of the basement membrane zone and the dermis.
Angiosarcoma: a complication of varicose leg ulceration
Authors: Al-Najjar AA , Harrington CI , Slater DN.
Published: August 2023

Most reports of skin malignancy associated with varicose ulceration have described carcinomatous change (1). The development of fibrosarcoma in varicose ulcers is considerably rare but has also been described (2). We report a case of angiosarcoma developing at the site of longstanding varicose ulceration.
Collagen components in the duodenal and rectal mucosa in progressive systemic sclerosis and other diseases
Authors: Hendel L , Ammitzbøll T , Dirksen K , Petri M.
Published: August 2023

Small intestinal mucosa from 14 patients suffering from progressive systemic sclerosis and 22 patients with various other diseases was analysed for collagen components. There was no significant difference in the concentration of hydroxyproline, hydroxylysine and proline between the two groups. Rectal mucosa from 11 progressive systemic sclerosis patients, 5 patients with ulcerative colitis and 7 patients with various other diseases was analysed for collagen components. No significant difference was demonstrated in the concentration of hydroxyproline, hydroxylysine and proline between progressive systemic sclerosis patients and patients with various other diseases, but in patients with ulcerative colitis the concentration of hydroxyproline, hydroxylysine and proline were found to be significantly lower than in the two other groups.
Pituitary function and DHEA-S in male acne and DHEA-S, prolactin and cortisol before and after oral contraceptive treatment in female acne
Authors: Palatsi R , Reinilä M , Kivinén S.
Published: August 2023

Pituitary function (TRH-LHRH stimulation test) was investigated in male acne patients and serum levels of dehydroepiandrosterone sulphate (DHEA-S), sex hormone binding globulin (SHBG) and other biochemical parameters were investigated in male acne patients and in female acne patients before and after treatment with an oral contraceptive. The TRH-LHRH stimulation test was performed with 15 male patients suffering from severe cystic acne and 7 healthy volunteers. Basal and stimulated prolactin, LH and FSH levels were statistically similar in the patients and control groups. However, the stimulated LH levels of the patients were 60% higher than those in controls. SHBG levels were significantly) higher in the patient group compared to those in the control group. Thirty-three female acne patients were randomly divided into two groups and treated for six months with an oral contraceptive containing 0.030 mg ethinylestradiol (EE) plus 0.150 mg levonorgestrel or 0.150 mg levonorgestrel. After six months´ treatment a 30% decrease in DHEA-S levels were observed in the desogestrel/EE group and a 15% decrease in the levonorgestrel/EE group; the difference was not statistically significant. At the same time serum total cortisol increased by 75-100% and free testosterone fell by 30-40% in both groups, whereas SHBG elevated 250% in the desogestrel/EE group and 30% in the levonorgestrel/EE group. Acne improved significantly in both groups, desogestrel/EE showing greater improvement. A decrease in SHBG and increase in DHEA-S levels appear to be the most common hormonal changes in acne. Oral contraceptive treatment induces an increase in SHBG and decrease in DHEA-S and also improves acne.
Calmodulin levels in psoriasis: the effect of treatment
Authors: Tucker WF , MacNeil S , Dawson RA , Tomlinson S , Bleehen SS.
Published: August 2023

Epidermal calmodulin levels were measured in lesional and non-lesional skin in 20 psoriatics before and after treatment by a variety of established topical and systemic regimes. Pretreatment, 10 out of 20 patients showed elevated calmodulin levels in lesional epidermis. Clearance of psoriatic plaques was accompanied by a significant overall reduction (p less than 0.05) in epidermal calmodulin, irrespective of the treatment regime used. For the non-lesional epidermis, only 5 out of 17 patients initially showed elevated calmodulin levels and there was no significant reduction in those levels following treatment.
Reduced levels of histidine and urocanic acid in suction blister fluids from patients with psoriasis
Authors: Juhlin L , Shroot B , Martin B , Caron JC.
Published: August 2023

Metabolites of histidine were determined by high performance liquid chromatography in suction blister fluids from lesions and normal appearing skin of patients with psoriasis and from healthy subjects. There was a significant decrease in the levels of histidine and urocanic acid in the samples obtained from patients with psoriasis as compared to healthy subjects. Virtually only the E-isomer of urocanic acid was detected.
Free and total plasma testosterone in men and women with acne
Authors: Sultan C , Oliel V , Audran F , Meynadier J.
Published: August 2023

Androgens are important in the pathogenesis of acne, and free testosterone in the serum is regarded as the biologically active component. In this study, serum free and total testosterone levels were measured in men (34) and women (14), suffering from acne but otherwise healthy. The plasma values for both groups of patients did not differ significantly from those of the age matched control groups.
Effects of retinoids on type IV collagenolytic activity in melanoma cells
Authors: Oikarinen A , Salo T.
Published: August 2023

The effects of retinol, all-trans-retinoic acid, isotretinoin and etretinate on the activity of basement membrane collagen degrading enzyme was studied in melanoma cells. The results indicated that retinoids at concentrations of up to 10(-6) M did not significantly affect type IV collagenolytic activity in these cells in vitro. Since type IV collagenolytic enzyme may be involved in the metastatic potential of tumour cells, it appears that retinoids do not affect the metastatic potential of melanoma cells by affecting type IV collagenolytic activity.
Acquired zinc deficiency in two breast-fed mature infants
Authors: Kuramoto Y , Igarashi Y , Kato S , Tagami H.
Published: August 2023

Zinc deficiency was diagnosed in a breast-fed mature infant and her sister. In both infants the characteristic dermatitis appeared on the face and buttocks around 10 weeks of age. It responded rapidly to zinc supplements. Their mother´s serum zinc level was slightly low but her milk was found to be remarkably low in zinc. Oral zinc supplementation could correct only her serum zinc level but not her low breast milk zinc level. Therefore the mother´s deficiency in the transfer process of zinc from serum to breast milk was suspected as a cause of the skin changes in her children. These cases indicate that even mature infants, who feed exclusively on mother´s milk, run a risk to develop zinc deficiency, if the concentration of zinc in the breast milk is very low.
Pyrogallol in the tumour stage of mycosis fungoides: a case report
Authors: Van de Kerkhof PC.
Published: August 2023

The case history of a patient with mycosis fungoides (tumour stage) is reported. As ultimum refugium pyrogallol 5% in petrolatum proved to be remarkably effective.
Detection of leukotrienes in the serum of asthmatic and psoriatic patients
Authors: Uotila P , Punnonen K , Tammivaara R , Jansén CT.
Published: August 2023

Purified serum samples from asthmatic and psoriatic patients and healthy controls were analysed by high-pressure liquid chromatography (HPLC) and the amounts of leukotrienes were measured from the corresponding HPLC fractions by specific radioimmunoassays. In the serum of healthy controls the amounts of leukotrienes B4, C4 and D4 were very small or negligible. Rather great amount of leukotriene B4 was, however, detected in the serum of many asthmatic and psoriatic patients. The amount of leukotriene B4 was in the serum of asthmatic patients 120 +/- 20 pmol/ml (n = 11, mean +/- SEM) and in that of psoriatic patients 100 +/- 10 pmol/ml (n = 10). The amounts of leukotrienes C4 and D4 were rather small in the serum of most patients. The amount of leukotriene C4 was, however, very high (250 pmol/ml) in the serum of a psoriatic patient. Significant amount of leukotriene D4 was also detected in the serum of this patient. The present study indicated that leukotrienes are formed during blood clotting in the leukocytes of asthmatic and psoriatic patients and that the rate of formation is so high that leukotrienes may have a role in these diseases.
In vitro propagation of tissue-infiltrating lymphoid cells from lesional skin by culture in IL 2-containing medium
Authors: Aiba S , Tagami H.
Published: August 2023

Using an in vitro culture system, we have propagated lymphoid cells infiltrating the tissues of allergic contact dermatitis and several inflammatory dermatoses, and those drawn from the blister observed at the sites of allergic contact dermatitis. Approximately 10(7) cells were eventually obtained after 3 weeks from 3 mm punch-biopsied tissues by their culture in human IL 2-containing medium. Studies by flow-cytometrical analysis demonstrated that the proliferated cells were composed of 32-88% Leu-1-bearing (Leu-1+) cells, 70-90% Leu-2a-bearing (Leu-2a+) cells, 10-40% Leu-3a-bearing (Leu-3a+) cells, 70-90% HLA-DR-bearing (HLA-DR+) cells, and less than 10% Tac (IL 2 receptor)-bearing (Tac+) cells. Only the cultured cells derived from lesional tissue of pityriasis rosea and those from the blister content of contact dermatitis showed low percentage of T cell phenotype-bearing cells. These results suggest that the described method has opened a new system that enables us to culture possible effector lymphoid cells actually infiltrating various lesional skin.
HLA genotypes in a family with a case of homozygous C2 deficiency and discoid lupus erythematosus
Authors: Braathen LR , Bratlie A , Teisberg P.
Published: August 2023

A fifty-year-old man with a history of recurrent bronchial and renal infections, and rheumatoid arthritis was admitted with a sunexposure-induced discoid lupus erythematosus. Complement levels and HLA typing of the patient and his family revealed a homozygous C2 deficiency in the patient and his HLA-identical healthy younger sister. The C2 deficiency gene was associated with HLA-A10, B18, DR2, C4A4B2, BfS on one chromosome and with HLA-A2, B7, DR2, C4A4B2, BfS on the other.
Treponema pallidum in human chancre tissue: an electron microscopic survey
Authors: Poulsen A , Kobayasi T , Secher L , Weismann K.
Published: August 2023

In biopsies obtained from syphilitic chancres of varying ages in 10 patients, a total of 766 ultrathin sections of Treponema pallidum were studied by electron microscopy. The course and number of axial filaments observed reveal that one bunch of 3-4 filaments without interruption entwine the whole cytoplasmic body. In 9.2% of the sections a trilaminar or a fragmentary trilaminar periplastic membrane was observed outside the cytoplasmic membrane and the axial filaments. The occurrence of the periplastic membrane decreased with advancing ages of the chancres. A protective function of the membrane is discussed. A peritreponemal fine reticular halo demonstrable in most fragments is supposed to be due to fixation induced shrinkage of treponemal hyaluronidase-influenced semifluid glycosaminoglycans. Peritreponemal reticular halos were also observed in collagen tissue. A destructive effect of the treponemes on collagen fibres could explain how the organisms penetrate through the collagen rich meninges into the central nervous system. A surface associated narrow border of electron dense amorphous substance, probably originating from the host organism, yields to tangentially cut treponemes a spiny caterpillar-like appearance.
Reticular erythematous mucinosis syndrome in a patient with polyarthritis
Authors: Dijkmans BA , Bergman W , Eulderink F , Meijers KA.
Published: August 2023

A patient with seronegative oligoarthritis who developed the reticular erythematous mucinosis (REM) syndrome is described. This syndrome is considered to be a dermatological entity unrelated to systemic disorders. Aggravation of the rash by exposure to sunlight and a good response to anti-malarial agents suggest a relationship with rheumatological disorders, e.g. rheumatoid arthritis and systemic lupus erythematosus. Dermatologists consulted by a patient with the REM syndrome should be aware of the possibility of an associated rheumatological disease.
Topical application of potent glucocorticoids augments epidermal beta-adrenergic adenylate cyclase response in vivo
Authors: Kajita S , Iizuka H , Hirokawa M , Tsutsui M , Mizumoto T.
Published: August 2023

The effects of topical application of glucocorticoids on the epidermal beta-adrenergic adenylate cyclase response were investigated. A significant increase in this receptor response was observed 24 h following topical application of potent glucocorticoid ointments (0.12% betamethasone-17-valerate, 0.05% clobetasol-17-propionate). The application of a relatively weak glucocorticoid, hydrocortisone-17-butyrate, revealed no augmentation effect. There was no significant difference in other adenylate cyclase responses (adenosine-, and histamine-) between control and glucocorticoid-treated epidermis. UVB irradiation is known to augment the beta-adrenergic response of epidermis. Comparison of the effects revealed that topical glucocorticoid treatment had less effect than UVB irradiation, and when the UVB irradiation was combined with glucocorticoid treatment, the beta-adrenergic augmentation effect was not enhanced. Cyclic AMP phosphodiesterase activities were not significantly altered by the glucocorticoid-, UVB-, or combined treatments. Our data indicate that epidermal beta-adrenergic adenylate cyclase response is affected by topical application of ´potent´ glucocorticoids in vivo. Although the effect is weaker than that induced by UVB irradiation, we believe the system might be a useful tool for dissecting the glucocorticoidal potency of topical preparations using the epidermal keratinocyte response in vivo.
Antithrombotic agents in necrobiosis lipoidica
Authors: Bonnetblanc JM , Julia A , Rigaud M.
Published: August 2023

No abstract available.
Presence of chemotactic peptides other than C5a anaphylatoxin in scales of psoriasis and sterile pustular dermatoses
Authors: Takematsu H , Terui T , Ohkohchi K , Tagami H , Suzuki R , Kumagai K.
Published: August 2023

A unique leukocyte chemotactic factor of around 12 kD molecular weight has been suggested to be responsible for the mechanisms involved in transepidermal migration of leukocytes observed in psoriasis and related sterile pustular dermatoses. Although we confirmed with radioimmunoassay the presence of a C5-cleavage product in the chemotactic fractions from psoriatic scale extract eluted by gel filtration HPLC, the neutrophil chemotactic activity demonstrated in the peak fraction was only partially inhibited by rabbit antiserum to human C5a, whereas that noted in the peak fraction, prepared from zymosan activated serum, was totally abrogated by the same treatment. Similarly the chemotactic fraction prepared from the scale extracts of other related pustular dermatoses were only partially inhibited with anti-C5a antiserum. These findings suggest that chemotactic peptides other than C5a also play a role in the transepidermal migration of leukocytes in these dermatoses.
Surface Properties of Resin Composites and CAD/CAM Blocks After Simulated Toothbrushing
Authors: Suzuki M , Miyano Y , Sato F , Shinkai K
Published: August 2023

Objectives

This study aimed to evaluate the surface gloss, surface roughness, and color change of restorative materials after a three-body wear abrasion.

Methods and Materials

Four resin composites with different filler particle size (Gracefil Flo [GFF, 0.7 μm], Gracefil LoFlo [GFL, 0.25 μm], Gracefil ZeroFlo [GFZ, 0.15 μm], and Gracefil Putty [GFP, 0.3 μm]), two CAD/CAM resin composite blocks with different filler particle size (Cerasmart 300 [CS3, 0.7 μm] and Cerasmart Prime [CSP, 0.3 μm], GC), and one CAD/CAM lithium disilicate glass-ceramic block (Initial LiSi Block [ILS], GC) as a control were evaluated. Twenty slab-shaped specimens were obtained from each material. Ten specimens were subjected to 80,000 toothbrushing strokes and measured for surface gloss (Gloss Unit, GU), surface roughness (Ra, μm), and color (L*, a*, and b* values) before toothbrushing and at every 20,000 strokes. Color differences (ΔL*, Δa*, Δb*, and ΔE00) before and after toothbrushing were calculated. After 80,000 strokes, abraded surfaces were observed using scanning electron microscopy. The other 10 specimens were measured for Vickers microhardness (VHN).

Results

After 80,000 toothbrushing strokes, the mean GU ranged from 60.43 to 16.12 (the highest for ILS and lowest for GFL), and the mean Ra ranged from 0.079 to 4.085 (the lowest for ILS and highest for GFL). At all measuring stages, the calculated ΔE00 values ranged from 0.31 to 0.92 for all materials. The mean VHN ranged from 632.34 to 39.08 (the highest for ILS and lowest for GFZ). The resin composite containing the largest filler particle (GFF) showed significantly lower Ra and higher VHN than other resin composites (GFL, GFZ, and GFP). The CAD/CAM resin composite block containing a smaller filler particle (CSP) retained significantly higher GU than that containing a larger filler particle (CS3). A negative correlation between GU and Ra was detected.

Conclusions

Based on the findings, toothbrush abrasion induced a decrease in GU and an increase in Ra for all resin-based materials tested. Resin-based materials with larger filler size tended to show lower Ra, while resin-based materials with smaller filler size tended to show a smaller reduction in GU. These were more pronounced for light-cure resin composites than for resin composite blocks for CAD/CAM.
Om å «måle» det som ikke kan måles
Authors: Kleven Thor Arnfinn
Published: August 2023

Det er viktig å være oppmerksom på at det som kalles måling i pedagogisk forskning er noe annet enn det man vanligvis kaller måling. Det er fordi de begrepene som studeres (kunnskaper, motivasjon, trivsel osv.) er abstrakte begreper som ikke kan observeres direkte. For å kunne foreta empiriske studier av slike begreper må man samle informasjon om indikatorer på begrepene, og det gjøres vanligvis gjennom direkte observasjon og/eller spørsmål. Slike «målinger» er nødvendigvis usikre, og derfor er det viktig å vurdere resultatene kritisk. Har vi «målt» det vi sier at vi har målt? Begrepsvaliditet kan defineres som samsvar mellom begrepet slik det er definert og begrepet slik det er «målt». Men samsvar mellom noe som er kjent og noe som ikke kan måles, kan heller ikke måles. Derfor må valideringsprosessen bestå i å samle evidens gjennom rasjonal argumentasjon støttet av empiriske data. Som følge av usikkerheten i målingen, og av andre validitetstrusler som kort nevnes i artikkelen, bør forskningsresultater regnes som konstruksjoner. Det er vanligvis riktigere å si «forskning tyder på at» enn «forskning har vist at». Dette er i samsvar med kritisk realisme, definert som kombinasjon av ontologisk realisme og epistemologisk konstruktivisme.
English abstract
On “Measuring” What Cannot be Measured
It is important to note that what is called measurement in educational research is something different from what is usually called measurement. This is because the concepts studied (knowledge, motivation, well-being, etc.) are abstract concepts that cannot be observed directly. In order to do empirical studies of such concepts, one must collect information from indicators of the concepts, and this is usually done through direct observation and/or questions. Such “measurements” are unsure, and it is important to assess the results critically. Have we “measured” what we say we have measured? Construct validity can be defined as correspondence between the concept as it is defined and the concept as it is “measured.” However, correspondence between something that is known and something that cannot be measured cannot be measured either. Therefore, validation can only take place by collecting evidence through rational argumentation supported by empirical data.
As a result of the measurement uncertainty and of other validity threats that are briefly mentioned in the article, research results should be considered constructions. It is usually more correct to say that “research suggests that” than to say “research has shown that.” This is in accordance with critical realism, defined as a combination of ontological realism and epistemological constructivism.
Collective agency as a leverage point in multi-actor innovation
Authors: Blix Germundsson Lisa , Ljung Magnus
Published: August 2023

The aim of this study is to investigate how horticultural firms meet their need for innovation within the innovation system. A comparative process ethnography approach was applied to two cases of long-term collaboration between multiple actors in Swedish horticulture. The retrospective reconstruction of the cases through documentation and interviews allowed for triangulation of data in a grounded theory approach. The leverage points of the developing collaborative processes were found to be; having agency and a network approach, the forming of collective agency through social learning, enhancing resource access, and operationalization of results. The concept of leverage points is useful for understanding evolutionary changes in multi-actor collaborations. The use of the concept of collective agency contributes to the understanding of the dynamics of demand articulation, illustrating a reciprocal process between the actors’ individual agencies, and evolving over time through their social learning. The results point to a need for policymakers and practitioners to develop a broader understanding of how actors work in the innovation system to enhance knowledge development and innovation.
The Comparison of Parameter Estimation in Exponential Distribution using Maximum Likelihood Method and Bayesian Method
Authors: Mada Grandianus , Salsinha Cecilia Noviyanti , Mun Beatrix Farena
Published: August 2023

This study aims to compare the parameter estimation process on the exponential distribution using the maximum likelihood method and the Bayesian method on service data at Bank BRI Atambua Branch. The result of processing data on 100 service time data obtained parameter values for the maximum likelihood method = 0,050942 and the Bayesian = 1,0008. By using the Akaike Information Criterion (AIC) feasibility test for these parameters, the AIC value for the maximum likelihood method was 797,4122 and the AIC value for the Bayesian method was 3.931,1002 so it can be concluded that the maximum likelihood method is better used to estimate parameters than Bayesian method.
Penentuan Pola Asosiatif Data Tracer Study Universitas Semarang dengan Algoritma Hash Based
Authors: Christioko Bernadus Very , Khoirudin Khoirudin , Nugroho Atmoko
Published: August 2023

Data hasil tracer study Universitas Semarang saat ini belum diolah ke dalam bentuk pola asosiatif yang dapat dimanfaatkan kampus guna memperoleh feedback evaluasikeberhasilan proses belajar mengajar yang telah dilaksanakan. Penelitian ini menggunakan metode data mining dengan algoritma Hash based untuk menemukan pola asosiatif dari data tracer study. Proses pembentukan pola asosiatif menggunakan tahapan yang ada pada Knowledge Discovery in Database yang meliputi proses cleaning data, integrasi, transformasi data, data mining, evaluasi pola dan representasi pengetahuan. Hasil penelitian dengan support minimal sebesar 50% dan confidence 75%, diperoleh pola datatracer study sebanyak 3 pola asosiatif. Pola yang dihasilkan ini dimaksudkan dapat untuk berkontribusi pada pengembangan kurikulum dan sarana penunjang dalam proses pembelajaran.
Penerapan metode Weighted Aggregated Sum Product Assessment (WASPAS) dalam menentukan reseller terbaik
Authors: Pungkasanti Prind Triajeng , Wakidah Nur , Kurniawan Rizal Rafli Fajar
Published: August 2023

Peran reseller penting dalam sebuah penjualan. Reseller yang berkompeten diperlukan untuk meningkatkan nilai penjualan. Pemberian apresiasi kepada reseller terbaik dapat memotivasi para reseller agar saling berkompetisi. DJ Foundation menerapkan penentuan reseller secara manual sehingga terjadi ketidakefektivan tenaga dan waktu, penumpukan data, kehilangan berkas, dan kesalahan penilaian. Dari permasalahan tersebut, maka dirancang sistem untuk menentukan reseller terbaik dengan menerapkan metode Weighted Aggregated Sum Product Assessment (WASPAS), dengan kriteria kejujuran, loyalitas, tanggung jawab, absensi, pinalti, dan target harian. Data yang diperoleh bersumber dari wawancara, observasi, dan studi pustaka. Penelitian ini menghasilkan kategori ranking terbaik dengan nilai akhir 0,973, sehingga layak digunakan oleh pengguna, karena dapat membantu mengurangi penumpukan ataupun kehilangan berkas, serta mempercepat dalam proses penentuan reseller.
Peran Kepemimpinan Kepala Sekolah dalam Mewujudkan Merdeka Belajar di Sekolah Kristen
Authors: Lahagu Atozanolo , Hidayat Dylmoon
Published: August 2023

Principal leadership has an essential role in advancing learning activities in schools. This study aims to determine the role of the principal's leadership in realizing the Freedom of Learning in Christian Schools. This study conducted a literature study to collect materials from books, journals, articles, and other sources related to school principals' leadership in realizing Independent Learning in Christian schools. The results of the study indicate that the principal's leadership role is (1) Responsible for teaching, encouraging, and directing the school community, (2) Planning, mobilizing, coordinating, and synchronizing all school resources, (3) Providing support in the implementation of the independent program of activities. Learning by preparing, financing, and documenting, (4) Creating a conducive school organizational culture, (5) Providing motivation, and (6) Carrying out various supervision and control.
PERAN DIGITALISASI DESA TERHADAP PERTUMBUHAN EKONOMI DI DESA KRANDEGAN, JAWA TENGAH
Authors: Rahoyo Stefanus , Slahanti Masine , Heriawan Bambang
Published: August 2023

Penelitian ini bertujuan menganalisis proses terjadinya digitalisasi desa serta pengaruhnya pada pertumbuhan ekonomi di Desa Krandegan, Jawa Tengah. Dengan pendekatan kualitatif, penelitian ini menemukan bahwa digitalisasi desa tersebut terjadi karena dimotori oleh seorang kepala desa yang berjiwa entrepreneur, didukung oleh generasi milenial yang melek dan tanggap teknologi digital, dan dipercepat oleh momentum Covid-19. Lebih jauh, dari sisi ekonomi, dampak langsung dari digitalisasi desa ini adalah membuka peluang pasar, menaikkan pendapatan desa lewat BUMDES, dan membuka kesempatan kerja. Sedangkan dampak tidak langsung dari digitalisasi desa ini adalah mengalirnya berbagai bantuan dan terbukanya jejaring. Semua dampak tersebut pada gilirannya meningkatkan kegiatan dan pertumbuhan ekonomi desa.
Food Safety and Law Enforcement in Türkiye
Authors: KAŞLI Dr. Enver
Published: August 2023

Food is an indispensable basic need for human beings. Food safety has become one of the elements of public order, as technological developments bring many new threats to food safety in contrast to the advantages it provides. Safe food does not pose a danger to human health, is ready for consumption, and complies with the legislation. Food law enforcement is an activity that requires technical knowledge and expertise and is among the private law enforcement agencies. To ensure food safety in Türkiye, the Ministry of Agriculture and Forestry carries out food law enforcement activities. In this study, food safety and food law enforcement organization, powers, and sanctions of food law enforcement are examined by Turkish legislation.
Integration of VLF-EM and VES data for pavement failure investigation in a typical basement complex terrain of southwestern Nigeria
Authors: Oyedele Akintunde A. , Bawallah Musa A. , Akinwamide Joshua T. , Ilugbo Stephen O. , Ogunyebi Segun N.
Published: August 2023

Geophysical investigations involving very low frequency electromagnetic (VLF-EM) and vertical electrical sounding (VES) techniques were deployed to study the pavement failure along a major road in a typical basement complex terrain of southwestern Nigeria. This study was designed to assess the failure and provide a basis for ultimate engineering design. The study delineated a 3- to 4-layer geoelectric sequence: a topsoil of thickness varying from 0.4 to 1.2 m, a spectrum of clayey materials of thickness varying from 1.9 to 14.5 m and a weathered/fractured basement occurring at depths of between 3.6 and 15.0 m. The shallow basement indicated low bearing capacity, with resistivity values ranging from 62.1 to 377.9 Ωm. The presence of clay/clayey materials, linear features and the effect of rising water table within the influence zone underlined the pavement failure. This information will facilitate appropriate designing, soil improvements and selection of materials for road construction that can stand the test of time.
Analysis of Lead (Pb) and Cadmium (Cd) in Oyster Crassostrea gigas and Saccostrea cucullata using Atomic Absorption and Ultraviolet-Visible Spectrophotometer Methods
Authors:   Chemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia, 23111., Lelifajri Lelifajri , Salsabila Salsabila , Suhud Khairi
Published: August 2023

Lead (Pb) and Cadmium (Cd) metals are highly toxic when accumulated in the body and cause serious diseases and even death. This study aimed to determine the metal content of Pb and Cd in the oyster species Crassostrea gigas and Saccostrea cucullate in the Lampulo and Krueng Cut areas at three different places. Analysis of the metals was carried out using AAS and UV-Visible spectrophotometers. Samples were prepared using concentrated HNO3 wet destruction and the addition of dithizone. The results showed Pb measured by AAS in Saccostrea cucullata 2.33-8.00 ppb, and by UV-Vis 2.77-8.66 ppb. Pb within Crassostrea gigas by AAS method 1.77-10.30 ppb, and by UV-Vis method 2.11-10.66 ppb. The Cd metal measured by AAS in Saccostrea cucullate is 3.80-10.50 ppb, and by UV-Vis method is 4.29-10.77 ppb, whereas Cd in Crassostrea gigas measured by AAS is 12.11-13.22 ppb and by UV-Vis method is 12.77-13.66 ppb. Linearity of Pb measurements with AAS and UV-Vis was obtained R2 =0.9979 and R2 =0.9938 and for Cd were R2 =0.9986 and R2 =0.9810. Accuracy (%recorvery) of Pb measurements by AAS and UV-Vis are 80-110% and 98-113% whereas Cd showed 100-106% and 91-107% respectively. The relative value of the standard deviation (%RSD ± SD) is 0.001 indicating excellent measurement results. Based on t-test calculations, measurements of Pb and Cd levels showed no difference between the AAS method and the UV-Vis method
Epidemiological Study of Breast Cancer in Erbil, Kurdistan Region
Authors: M. Khoshnaw SettingsSarkawt , R. Ganjo Aryan , S. Salih Mohammed
Published: August 2023

Breast cancer is the most diagnosed cancer and the second leading cause of cancer death among women in the world. Compared to some other regions in the world, amount of information available about breast cancer epidemiology in the Kurdistan Region of Iraq is scarce. This study is an attempt to enrich our knowledge about different epidemiological aspects of breast cancer in the region since epidemiological studies contribute quite significantly to the current knowledge of environmental and genetic risk factors and to the current treatment strategies for breast cancer. In addition, studies has shown that the past and ongoing research has a massive implication in improving the outcome of this common disease. This work takes all women diagnosed with breast cancer at Nanakaly Hospital in Erbil, Iraq as sample of the study. Patient characteristics were captured then statistical analysis was performed on these data sets. The majority of patients were found to be city dwellers and about 46% were diagnosed at stage II and 40% at stage III. The vast majority of cases tested positive for hormone receptors but negative for HER2.
Transtorno de pânico
Authors: Nardi Antonio Egidio , Bernik Márcio Antonini
Published: August 2023

O transtorno do pânico é uma doença que se caracteriza pelas crises de ansiedade repentinas com inúmeros sintomas físicos, sensação de desespero ou medo intenso, muitas vezes sem motivo aparente. Essas crises duram alguns minutos e neste período a pessoa tem a impressão de que não possui mais controle sobre si, que irá morrer ou enlouquecer. A ciência ainda não descobriu quais as causas do transtorno de pânico, mas acredita-se que fatores como o estresse, genética, temperamento suscetível ao estresse, associadas às mudanças na forma como o cérebro funciona e reage a determinadas situações podem vir a desencadear a doença.
Quando é necessária a internação psiquiátrica?
Authors: Cordeiro Júnior Quirino , Gebara Marcos , Gorender Miriam Elza
Published: August 2023

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Evaluation of alpha- amylase activity in serum and saliva of normal individuals and patients with jaundice
Authors: H. Eddan Hazim , F. AI Dahhan Jinan , N. Al- Assee Wasan , F. Sulaiman Barak
Published: August 2023

Enzymes are very important components in the biological system. a-Amylase is one of these enzymes, it is one of the hydrolytic enzymes that breaks down the dietary starch and glycogen to glucose and maltose. The present study is conducted to evaluate a-Amylase activity in serum and saliva of patients with jaundice in comparison it with the enzyme activity in the serum and saliva of healthy individuals. That is, to provide further information about the relationship between jaundice and a­Amylase activity. Estimation of a-Amylase activity in serum and saliva was made by Amyloclastic (iodometric) method. A 120 samples of serum and saliva were collected; 50 samples represented the control group whose ages range between (20-55) years and 70 samples were the patient with jaundice group whose ages range between ( 15-55) years. Alpha-amylase activity appeared significantly higher in normal individuals (both in serum and saliva in comparison with patients with jaundice.
The relaxant effect of some drugs and aqueous extract of medicinal plants on bronchial smooth muscle in rabbits
Authors: H. Al-Jawad Faruk , Al-Jumaily Waseem
Published: August 2023

Histamine is a biogenic amine. that produces bronchospasm when it is used (I V) at.a.dose of 0.4 mg / kg in rabbits. It significantly reduced the ,e*- l"u"i. oi calcium (Ca) magnesium (Mg) and selenium (Se). (p < 0.05) . Forty rabbits were involved in this study. The serum ca, Mg and Se levels were measured before and after giving histamine and following [e administration oi aqueous extract of medicinal plants Cumi'um cyminum (cumin), Thymus vulgaris (thyme) and Anthemis nobilis (chamomile). ^ The serum Ca, Mg and Se levels of were highly elevated after treatment with extract cumin or chamomile in rabbits pretreated with histamine, the resurts of ca were changed lrom 8.34+ 0.40 and 8.79+ 0,27 to 33.41+ 0.50 and 97.62 ! 7.2 1tg /dl respectively while that of Mg from 20.20+ 0.37 and 19.47+ 0.31 to 74.97+ 0.ii and 89.14+ 1.41 pg /dl where as the serum level of Se was changed from 137.9g+ 0.4g and 145 36 + 0.66 ro 302.69 ! 0.6g and 245.4r,' 0.g1 pg /direspectivery .All these results were significant at p<0.05. The aqueous extracts of cumin or chamomile were used orally at a dose of 1.5 gm /kg in rabbits to relieve the bronchospasm and symptoms of dyspnea induced iy histamine. These results indicated crearly the po*iuiiity of using these extracts flr patients with chronic asthma after the adjustment ofthe effective dose.
Synthesis and study the biological activity of some new derivatives of 1,2,4-triazole compounds
Authors: H. Abed Elwahab Al-Somaidai Gazwan
Published: August 2023

Some derivatives of triazoles have been synthesized . These derivatives (Schiff's bases) were resulted from the reaction of (3-( 4-methoxy phenyl)-4-amino-5 mercapto-1,2,4-triazole and the corresponding substituted benzaldehydes in presence of glacial acetic acid . The chemical structures of the products were characterized by IR and UV spectra, elemental analysis C.H.N and the biological activity were studied against different kinds of bacteria.
The role of corporate universities in the modern world
Authors: Shirinkina Elena Viktorovna
Published: August 2023

The relevance of the research is due to the fact that corporate universities are experiencing an era of transformation today. Despite the rapid growth in the last 20 years of the population of corporate universities around the world, including in Russia, their global and regional associations are young and logically focus on the development of formats for the exchange of experience of their participants and, to a lesser extent, other tools for the institutionalization of the professional community. The subject of this research is to identify and review the main factors influencing the transformation of the role of corporate universities in the modern world, and the key global trends in corporate education to date. In the course of the work, the best practices and cases of the largest companies were analyzed. The empirical basis of the study was the cases of Sberbank Corporate University, Engie, Lufthansa, Unilever, GlobalCCU, etc. Each analyzed source was evaluated for the content of information about factors that affect and may affect corporate training, and global trends in the field of corporate training. The scientific novelty of the research consists in determining the factors influencing the trends of corporate training, their prioritization and a structured description of the identified factors and trends. The practical significance of this research lies in determining the role of a corporate university in the modern world, which will allow companies to form drivers of all transformations: business, operations, technologies and people.
Pedagogical conditions for the training of employees of the Ministry of Internal Affairs of Russia for the use of physical force and firearms
Authors: Krokhina Yuliya Valer'evna
Published: August 2023

In his work, the author examines in detail topical issues related to the professional training of employees of the Ministry of Internal Affairs of the Russian Federation for the use of physical force and firearms during the performance of official duties. The analysis of research in this area has been carried out, the opinions of specialists, scientists and practitioners have been studied, who have largely come to the conclusion that, as a rule, the use of weapons and physical force to neutralize offenders and detain criminals occurs mainly in extreme situations. The solution of operational official tasks should be handled by professionally trained competent specialists who clearly and competently understand the nuances of their official activities, are able to comprehensively analyze their personal and business qualities and make effective decisions related to the performance of functions assigned to the Ministry of Internal Affairs of the Russian Federation. For this purpose, the author has studied the pedagogical aspects of the topic. The main conclusions of the research conducted by the author are the circumstances that in the system of additional professional education, in particular in the All-Russian Institute for Advanced Training of Employees of the Ministry of Internal Affairs of Russia, a huge practical and theoretical experience has been accumulated, starting from which we can say with confidence that we, the police, the teaching staff and individuals those who have been trained have something to respond to new challenges and threats to society. The chosen topic allowed the author to analyze the problems, identify the most acute pain points, as a result of which, relying on empirical, theoretical, qualitative, as well as pedagogical research methods, to consider key issues related to the peculiarities of education and professional training of employees of the internal affairs bodies of the Russian Federation.
ENTRE O ESTILO E A CONDIÇÃO SOCIAL
Authors: Da Silva Marcos Paulo
Published: August 2023

RESUMO – Baseado em um diálogo teórico-metodológico com a teoria literária, o artigo de natureza ensaística busca caracterizar o jornalismo imersivo como gênero híbrido discutindo os eixos e níveis de fusão e apropriação entre diferentes padrões expressivos que tensionam a estabilidade das fronteiras dos formatos jornalísticos tradicionais. Além disso, procura identificar as características desta modalidade de jornalismo que são mobilizadas na construção de uma premissa de relegitimação do campo profissional no interior dos paradoxos em que elas emergem. O debate sustenta-se no argumento central de que no âmbito do jornalismo imersivo estabelece-se uma mediação hegemônica entre um estilo narrativo – um modo jornalístico de narrar – e a condição social – um padrão cultural hegemônico caracterizador do tempo presente, neste caso demarcado pelos imperativos da chamada cultura empreendedora.
ABSTRACT – Based on theoretical and methodological dialogue with literary theory, this article aims to characterize immersive journalism as a hybrid genre by discussing the appropriation and combination of varying forms of expression and how they stretch the limits of traditional journalistic formats. Moreover, it seeks to identify the characteristics of this type of journalism used to re-legitimize the professional field within the paradoxes in which they emerge. The debate centers around the main argument that, in the context of immersive journalism, a hegemonic mediation is established between a narrative style (a journalistic way of narrating) and the social condition (a hegemonic cultural pattern representative of contemporaneity) which is demarcated by the demands of entrepreneurial culture.
RESUMEN – A partir de un diálogo teórico-metodológico con la teoría literaria, el artículo de estilo de ensayo busca caracterizar el periodismo inmersivo como un género híbrido, discutiendo los ejes y niveles de fusión y apropiación entre diferentes patrones expresivos que tensionan la estabilidad de las fronteras de los formatos periodísticos tradicionales. Además, busca identificar las características de esta modalidad de periodismo que se movilizan en la construcción de una premisa de relegitimación del campo profesionaldentro de las paradojas en las que emergen. El debate se basa en lo argumento central de que en el contexto del periodismo de inmersión se establece una mediación hegemónica entre un estilo narrativo – una forma periodística de narrar – y la condición social – un patrón cultural hegemónico que caracteriza el tiempo presente, en este caso demarcado por los imperativos de la llamada cultura empresarial.
Development of Anomaly Detection System Based on Distributed Log Tracing
Authors: Khudyakov D. A.
Published: August 2023

Software system developers must respond quickly to failures in order to avoid reputational and financial losses for their customers. Therefore, it is important to detect behavioral anomalies in the operation of software systems in a timely manner. At the moment, various tools for automatic monitoring of systems are being actively developed, but logs are the main tool for analyzing failures. Logs contain information about the operation of the system at various points of execution. Modern systems often have a distributed microservice architecture, which significantly complicates the task of analyzing logs. Logs of such systems are collected centrally from different microservices, forming a huge flow of information that is very difficult to analyze manually.  However, the problem of identifying logs related to a specific request to the system is solved by distributed tracing, the use of which opens up wide opportunities for the introduction of automatic analysis. There are already many solutions for detecting anomalies in logs, but they do not take advantage of distributed tracing. The article is considered to solving the problem of detecting behavioral anomalies in the work of distributed software systems based on automatic analysis of log traces. The solution is based on the synthesis of machine learning methods. Log traces are preprocessed and cleaned using process mining methods. Next, vectorization and clustering of log messages is performed. After that, a long short-term memory network (LSTM) is used to analyze deviations in the sequences of processed logs. As a result of the work performed, a prototype of the anomaly detection system was developed and tested.