bluuebunny/crossref_metadata_2025 huggingface dataset:
Ethical Issues for Direct-to-Consumer Digital Psychotherapy Apps: Addressing Accountability, Data Protection, and Consent
Authors: Martinez-Martin Nicole , Kreitmair Karola
Published: April 2018

This paper focuses on the ethical challenges presented by direct-to-consumer (DTC) digital psychotherapy services that do not involve oversight by a professional mental health provider. DTC digital psychotherapy services can potentially assist in improving access to mental health care for the many people who would otherwise not have the resources or ability to connect with a therapist. However, the lack of adequate regulation in this area exacerbates concerns over how safety, privacy, accountability, and other ethical obligations to protect an individual in therapy are addressed within these services. In the traditional therapeutic relationship, there are ethical obligations that serve to protect the interests of the client and provide warnings. In contrast, in a DTC therapy app, there are no clear lines of accountability or associated ethical obligations to protect the user seeking mental health services. The types of DTC services that present ethical challenges include apps that use a digital platform to connect users to minimally trained nonprofessional counselors, as well as services that provide counseling steered by artificial intelligence and conversational agents. There is a need for adequate oversight of DTC nonprofessional psychotherapy services and additional empirical research to inform policy that will provide protection to the consumer.
Adaptation and Implementation of a Mobile Phone–Based Remote Symptom Monitoring System for People With Cancer in Europe (Preprint)
Authors: Furlong Eileen , Darley Andrew , Fox Patricia , Buick Alison , Kotronoulas Grigorios , Miller Morven , Flowerday Adrian , Miaskowski Christine , Patiraki Elisabeth , Katsaragakis Stylianos , Ream Emma , Armes Jo , Gaiger Alexander , Berg Geir , McCrone Paul , Donnan Peter , McCann Lisa , Maguire Roma
Published: April 2018

BACKGROUND

There has been an international shift in health care, which has seen an increasing focus and development of technological and personalized at-home interventions that aim to improve health outcomes and patient-clinician communication. However, there is a notable lack of empirical evidence describing the preparatory steps of adapting and implementing technology of this kind across multiple countries and clinical settings.

OBJECTIVE

This study aimed to describe the steps undertaken in the preparation of a multinational, multicenter randomized controlled trial (RCT) to test a mobile phone–based remote symptom monitoring system, that is, Advanced Symptom Management System (ASyMS), designed to enhance management of chemotherapy toxicities among people with cancer receiving adjuvant chemotherapy versus standard cancer center care.

METHODS

There were 13 cancer centers across 5 European countries (Austria, Greece, Ireland, Norway, and the United Kingdom). Multiple steps were undertaken, including a scoping review of empirical literature and clinical guidelines, translation and linguistic validation of study materials, development of standardized international care procedures, and the integration and evaluation of the technology within each cancer center.

RESULTS

The ASyMS was successfully implemented and deployed in clinical practices across 5 European countries. The rigorous and simultaneous steps undertaken by the research team highlighted the strengths of the system in clinical practice, as well as the clinical and technical changes required to meet the diverse needs of its intended users within each country, before the commencement of the RCT.

CONCLUSIONS

Adapting and implementing this multinational, multicenter system required close attention to diverse considerations and unique challenges primarily related to communication and clinical and technical issues. Success was dependent on collaborative and transparent communication among academics, the technology industry, translation partners, patients, and clinicians as well as a simultaneous and rigorous methodological approach within the 5 relevant countries.
Online Health Information Seeking and eHealth Literacy Among Patients Attending a Primary Care Clinic in Hong Kong: A Cross-Sectional Survey (Preprint)
Authors: Wong David Ka-Ki , Cheung Man-Kuen
Published: April 2018

BACKGROUND

Previous studies have suggested that patients’ online health information seeking affects their medical consultations and patient-doctor relationships. An up-to-date picture of patients’ online health information-seeking behaviors can inform and prepare frontline health care professionals to collaborate, facilitate, or empower their patients to access and manage health information found online.

OBJECTIVE

This study explores the prevalence, patterns, and predictors of online health information-seeking behaviors among primary care patients in Hong Kong, and the relations between online health information seeking and electronic health (eHealth) literacy.

METHODS

Patients attending a university primary care clinic in Hong Kong were asked to complete a questionnaire survey on their demographic backgrounds; health status; frequency and pattern of online health information seeking; contents, sources, and reasons for online health information seeking; and their eHealth literacy. eHealth literacy was measured by the validated eHealth Literacy Scale (eHEALS). Regression analyses explored various demographic and behavioral predictors to online health information seeking, and predictors to eHealth literacy.

RESULTS

In all, 97.32% (1162/1194) respondents used the internet, of which 87.44% (1016/1162) had used the internet to find health information. Most respondents (65.97%, 665/1008) searched once monthly or more. Few (26.88%, 271/1008) asked their doctor about health information found online, but most doctors (56.1%, 152/271) showed little or no interest at all. The most sought topic was symptom (81.59%, 829/1016), the top reason was noticing new symptoms or change in health (70.08%, 712/1016), the most popular source was online encyclopedia (69.98%, 711/1016), and the top reason for choosing a source was convenience (55.41%, 563/1016). Poisson regression analysis identified high eHEALS score, fair or poor self-rated health, having a chronic medical condition, and using the internet several times a day as significant predictors of online health information seeking. Multiple regression analysis identified lower age, better self-rated health, more frequent internet use, more frequent online health information seeking, and more types of health information sought as significant predictors to higher eHealth literacy.

CONCLUSIONS

Online health information seeking is prevalent among primary care patients in Hong Kong, but only a minority shared the information with doctors. Websites were chosen more for convenience than for accuracy or authoritativeness. Doctors should recognize patients’ online health information-seeking behavior, and facilitate and empower them to search for high-quality online health information.
Development of an Educational Program to Increase Patient Involvement in a Healthcare Patient Portal: A Quality Improvement Project (Preprint)
Authors: Stone Cheryl , Faett Becky , Magdic Kathy
Published: April 2018

BACKGROUND

Efforts in the United States to improve patient engagement and communication with health care providers have led to the creation of the meaningful use program. [1] The Centers for Medicare and Medicaid Services have created a three-stage process to encourage the adoption and use of electronic health records (EHR). Benefits of EHR use include the ability to provide accurate, up-to-date, legible, and complete information about patients at the point of care. One important component of EHR is the patient portal. Patient portals provide 24-hour access to portions of a patient medical record as well as a secure pathway to send messages to providers, ask for refills of medications, and schedule appointments.

OBJECTIVE

To assess if patients who have not used the patient portal will engage in using the portal after an in-office orientation on how to access and the benefits of using the patient portal.

METHODS

A quality improvement project was performed using a convenience sample of 60 participants who were scheduled for an appointment in an outpatient cardiology office and had not accessed the patient portal in the past 12 months. The participants were given a survey regarding their computer and internet access as well as their level of comfort using a computer. Each participant was assisted in creating a username and password as well as a security question and answer. The participant then accessed the portal and navigated through the portal with the guidance of the nurse practitioner. They also sent a message via the portal to the provider they were assigned to that day. Each participant was given a pamphlet and a printed power point to reinforce what they had learned. After two months, the nurse practitioner accessed the portal to determine if the enrolled participants had accessed the portal. The reasons for access and frequency were recorded. If there was no access, the participant was called by the nurse practitioner to determine the reason they had not accessed the portal.

RESULTS

Of the 60 participants, 54% were women, 46% men, 93% were Caucasian. Fifty-six point seven accessed the portal from home. Reasons for access included: 85% reviewed labs, 53% reviewed messages sent to them from the office and 23% sent messages to the office. Twenty-four participants did not access the portal. Of those participants, 33% stated that they had no clear reason to access the portal, 25% stated that they forgot their login information and 17% stated they no interest in the portal.

CONCLUSIONS

Patient portals are a useful tool for communication between patients and their providers. Providing an in-office orientation to the portal increased patient access to the portal.
Effects of a Mindfulness Meditation App on Subjective Well-Being: Active Randomized Controlled Trial and Experience Sampling Study (Preprint)
Authors: Walsh Kathleen Marie , Saab Bechara J , Farb Norman AS
Published: April 2018

BACKGROUND

Mindfulness training (MT) includes a variety of contemplative practices aimed at promoting intentional awareness of experience, coupled with attitudes of nonjudgment and curiosity. Following the success of 8-week, manualized group interventions, MT has been implemented in a variety of modalities, including smartphone apps that seek to replicate the success of group interventions. However, although smartphone apps are scalable and accessible to a wider swath of population, their benefits remain largely untested.

OBJECTIVE

This study aimed to investigate a newly developed MT app called Wildflowers, which was codeveloped with the laboratory for use in mindfulness research. It was hypothesized that 3 weeks of MT through this app would improve subjective well-being, attentional control, and interoceptive integration, albeit with weaker effects than those published in the 8 week, manualized group intervention literature.

METHODS

Undergraduate students completed 3 weeks of MT with Wildflowers (n=45) or 3 weeks of cognitive training with a game called 2048 (n=41). State training effects were assessed through pre- and postsession ratings of current mood, stress level, and heart rate. Trait training effects were assessed through pre- and postintervention questionnaires canvassing subjective well-being and behavioral task measures of attentional control and interoceptive integration. State and trait training data were analyzed in a multilevel model using emergent latent factors (acceptance, awareness, and openness) to summarize the trait questionnaire battery.

RESULTS

Analyses revealed both state and trait effects specific to MT; participants engaging in MT demonstrated improved mood (r=.14) and a reduction of stress (r=−.13) immediately after each training session compared with before the training session and decreased postsession stress over 3 weeks (r=−.08). In addition, MT relative to cognitive training resulted in greater improvements in attentional control (r=−.24). Interestingly, both groups demonstrated increased subjective ratings of awareness (r=.28) and acceptance (r=.23) from pre- to postintervention, with greater changes in acceptance for the MT group trending (r=.21).

CONCLUSIONS

MT, using a smartphone app, may provide immediate effects on mood and stress while also providing long-term benefits for attentional control. Although further investigation is warranted, there is evidence that with continued usage, MT via a smartphone app may provide long-term benefits in changing how one relates to their inner and outer experiences.

CLINICALTRIAL

ClinicalTrials.gov NCT03783793; https://clinicaltrials.gov/ct2/show/NCT03783793 (Archived by WebCite at http://www.webcitation.org/75EF2ehst)
Future Developments in Tax Policy
Authors: Bird Richard M , Mintz Jack M
Published: April 2018

Only a few years ago, the future of tax policy seemed clear to all. The rhetoric, and to some extent the reality, of tax policy were dominated by the image of “levelling the playing field”, and the much-touted phenomenon of “globalisation” was taken to mean that the field was likely to be levelled somewhere close to a common denominator. Governments were no longer growing, the “welfare state” was increasingly seen as obsolete, and only the occasional out-of-touch crank seemed at all concerned about the redistributive consequences of reducing taxes on wealth and high incomes.
State Taxation: Unrequited Revenue and the Shadow of Section 90
Authors: McLeod Neil
Published: April 2018

This paper asks whether much State taxation is currently avoiding proper constitutional scrutiny, including the issue of its compliance with s 90 of the Commonwealth Constitution. That provision gives sole power to the Commonwealth to levy duties of customs and excise. The second part of the paper argues that the current interpretation of s 90 is in any event not capable of a sensible application to State laws.
Tax Avoidance in Australia: Results and Prospects
Authors: Passant John
Published: April 2018

The recent High Court decision of FCT v Peabody has raised once again the question of tax avoidance and how to deal with it. This article is a contribution to the discussion. The first part of the paper looks at the history of the judicial treatment of s 260, the old general anti-avoidance provision in the Income Tax Assessment Act 1936 (Cth) (the Assessment Act). There is then an analysis of Part IV A, s 260's bastard child, and the Peabody decision. I apply some of the historical lessons that come from the examination of s 260 to Part IV A. I am, if you like, looking back to look forward.
Identification of Protease Producing Halophilic Bacteria from Bledug KuwuMud Volcano
Authors: Rohman Muhammad Saifur , Prijambada Irfan Dwidya , Indriyani Yohanna Anisa , Hendrosatriyo Heri
Published: April 2018

The objective of this research was to isolate and identify the halophilic bacteria from Bledug Kuwu-mudvolacano having an ability to produce proteolytic enzyme. From this work, 6 bacterial isolates were obtainedfrom mud and water samples using artificial sea water media after incubation at room temperature. Threeout of the 6 isolates (BKL-3, BKL-5, and BKA-1) were selected for further analysis. BKL-3, BKL-5 and BKA-1exhibited an ability to grow at salt concentration greater than 10%. BKL-3 could grow on media supplementedwith 15% of salt, meanwhile BKL-5 and BKA-1 could grow at 20% of salt, respectively. Furthermore, thoseisolates also exhibited proteolytic activity when they were grown on casein media. The phylogenetic analysisbased on the 16SrRNA gene sequences showed that the BKL-3 belong to the group of Bacillaceae, whilst BKL-5and BKA-1 isolates were relatively distance from the group of Halomonadaceae. Therefore, BKL-5 and BKA-1could be considered as the allegedly new species that were separated from Halomonadaceae
Genetic Variation of Apolipoprotein E (ApoE) in Surabaya, Palu and Alor Populations of Indonesia
Authors: Hastuti Pramudji , Sofro Abdul Salam Mudzakir , Asdie Ahmad Husain , Sadewa Ahmad Hamim
Published: April 2018

Apolipoprotein E (ApoE) has been considered to play an important role in cardiovascular disorders.Several studies reported that genetic variation in ApoE locus influence plasma lipoprotein level. The objectivesof this study was to compare the frequency of ApoE genotypes and alleles in some populations of Indonesia.One hundred and ninety five voluntarily unrelated apparently healthy individuals were recruited fromSurabaya, Palu and Alor representing the western, middle and eastern populations of Indonesia, respectively.Blood samples were collected from each subject for DNA extraction. The common allelic variants of ApoE werescreened using polymerase chain reaction (PCR) and restriction fragment length polymorphism. Three allelesi.e. ε2, ε3 and ε4 were identified and five genotypes i.e. ApoE ε2/ε2, ApoE ε2/ε3, ApoE ε3/ε3, ApoE ε2/ε4, ApoE ε3/ε4 were found in three populations studied, while ApoE ε4/ε4 was absent in Surabaya, representing the westernpopulations of Indonesia. The frequency of ε2, ε3 and ε4 alleles in the western population were 0.208, 0.701and 0.092 respectively; in the middle population were 0.242, 0.618 and 0.140 respectively and in the easternpopulation of Indonesia were 0.267, 0.466 and 0.267 respectively. The highest frequency of ε2 and ε4 allelewas found in the eastern population of Indonesia. The distribution of ε2 allele were not significantly differentamong all Indonesian populations, but significantly different were found in ε3 and ε4 allele in the easternpopulation compared to those in the western and middle populations of Indonesian. It can be concluded thatthe frequency of three ApoE alleles in the western and middle populations of Indonesia was not significantlydifferent however, significantly different was observed in the frequency of ApoE ε3 and ε4 alleles from theeastern compared to those in the western and middle populations of Indonesia.
CYP3A4*1G gene Polymorphism on Javanese People
Authors: Sutrisna Em , Dwiprahasto Iwan , Kristin Erna
Published: April 2018

Most of drugs are metabolized by cytochrome P 450 (CYP) enzyme. Cytochrome P450 3A4 is thecytochrome that is involved in metabolizing more than 60% of all medicine used in human. The variationof this CYP3A4 gene will affect the catalytic activity of this enzyme. Recently, CYP3A4*1G in intron 10 wasfound in Chinese and Japanese population. There is a substitution of G to A at position 82266 in intron 10. Thepurpose of this research was to investigate the frequency of allele and genotype CYP3A4*1G. Samples weretaken from bloods of the subjects of the research. The examination of CYP3A4*1G was conducted by RTLP-PCRmethod.As the results of this research, the frequency of CYP3A4*1G in Javanese people is CYP3A4*1/*1 0.25,CYP3A4*1/*1G 0.55 and CYP3A4*1G/*1G 0.20. Frequency of allele G: 0.53, allele A: 0.47. The Fisher’s exact- testshows that the allele and genotype frequencyis p. 1.000. The allele and genotype frequency of Javanese peopleisstill in Hardy-Weinberg equilibrium.
A Development of Homolog Sequence of Eimeria tenella Partial Genome as a Probe for Molecular Diagnosis of Coccidiosis
Authors: Sumartono S.
Published: April 2018

The goal of the research was to develop a homolog sequence of Eimeria tenella partial genome as a molecularprobe for diagnose coccidiosis using dot blot method. A probe of homolog sequence of E.tenella partial genomeand a non radioactive label, dig-11-dUTP, were used for this research. Four concentrations of molecular probelabeled with dig-11-dUTP, namely, 158,33 pg/μl, 52,25 pg/μl, 15,83 pg/μl and 5,225 pg/μl were tested to detect0,6551 μg DNA target. The procedure of labeling and hybridization detection between DNA target with themolecular probe labeled with dig-11-dUTP were carried out with Digh high prime DNA labeling and detectionstarter Kit I. The conclusion of the research was that 52,25 pg/μl molecular probe or more which its sequenceGGCA CAGTATCCTCCTTCAGGGCAGGG CTCGCACTGGTCAAA CGCGG TAC CATT could detect DNAtarget by dot blot method.Keywords: coccidiosis, E. tenella genome, molecular probe, dot blot hybridization
Cloning and Sequencing cDNA Encoding for Rhoptry-2 Toxoplasma Gondii Tachyzoite Local Isolate
Authors: Artama Wayan T. , Sari Yulia , Subekti Didik Tulus , Poerwanto Soenarwan Hery , Subandono Jarot
Published: April 2018

Rhoptry protein belongs to an excretory and secretory antigens (ESAs) that play an important role during activepenetration of parasite into the cell target. This protein an able Toxoplasma gondii to actively penetrate targetedcell, meanwhile ESAs protein stimulates intracellular vacuole modification. It is, therefore, after the parasitesuccessfully enter the cell target then Granule (GRA) proteins are responsible for the formation of parasitophorusvacuole, which is protect the fusion with other intracellular compartments such as lysosomal vacuole. Consequently,this parasite is being able to survive and multiply at the cell target. The current study was aimed to clone andsequens cDNA encoding for ROP-2 of local isolated T. gondii tachizoite through DNA recombinant technique.Total ribonucleic acid (RNA) was isolated from tachyzoites of local isolated T. gondii that were grown up in Balb/c mice. Messenger RNA was isolated from total RNA using PolyAtract mRNA Isolation System. Messenger RNA wasused as a template for synthesis cDNA using Riboclone cDNA Synthesis System AMV-RT. EcoRI adaptor fromRiboclone EcoRI Adaptor Ligation System was added to Complementary DNA and than ligated to pUC19. Recombinantplasmid was transformed into E. coli (XL1-Blue). The transformed E. coli XL-1 Blue were plated on LB agarcontaining X-Gal, IPTG and ampicillin. Recombinant clones (white colony) were picked up and grown up in theLB medium at 37oC overnight. Expression of recombinant protein was analysed by immunoblotting in order toidentify cDNA recombinant wich is express ESA of T. gondii local isolate. Recombinant plasmid were isolatedusing alkalilysis method and were elektroforated in 1% agarose gel. The isolated DNA recombinant plasmid wascut using Eco RI and then sequenced through Big Dye Terminator Mix AB1 377A Sequencer using M13 Forward andM13 Reverse primers. The conclusion of this results showed that the recombinant clone was coding for excretoryand secretory protein which has molecular weight of 54 kDa. The DNA alignments of sequence from the clonedgene showed 97% homology with gene encoding for ROP-2 of T. gondii RH isolate.Keywords: Toxoplasma gondii, tachizoite, ESA, complementary DNA, ROP2
Distribution of Camphor Monooxygenase Genes in Soil Bacteria
Authors: Ngadiman N. , Suenaga Hikaru , Goto Masatoshi , Furukawa Kensuke
Published: April 2018

In microbial degradation of camphor, the first step is oxidation by multiunit enzyme, camphormonooxygenase, encoded by cam genes (camA,B,C). Seven camphor-utilizing bacterial strains have been isolatedfrom soil at various locations. CamA,B,C genes of Pseudomonas putida strain PpG1 and strain GF2001 were used asprobes to explore their abundance in the camphor-utilizing bacteria. Southern analysis revealed that all of thecam genes of GF2001 could hybridize well to the SpeI-digested genomic DNA of strains tested, whereas PpG1 camgenes were not. This result suggested that the GF2001 type cam genes are widely distributed among the camphorutilizingstrains in the environment. Thus strain GF2001 and seven newly isolated strains share a commonevolutionary origin.Key words: Camphor monooxygenase genes, gene distribution, sail bacteria.
Mineral Phosphate Solubilizing Bacteria Isolated from Various Plant Rhizosphere under Different Aluminum Content
Authors: Damarjaya Dolly Iriani , Widada Jaka , Senoo Keishi , Nishiyama Masaya , Otsuka Shigeto
Published: April 2018

The objectives of this study was to isolate and characterize the mineral phosphate solubilizing bacteriafrom rhizosphere and evaluate their potential as plant growth promoting bacteria in Al-toxic soils. The halozone formation method was used to isolate PSB using the media containing insoluble phosphates (Ca-P or Al-P)as a source of phosphate. Eight of acid and Al-tolerant PSB isolates that were able to solubilize Ca-P wereobtained from rhizosphere of clover, wheat, corn, and sunflower grown in Al-toxic soil. Identification of theisolates based on the 16S rRNA gene sequence analysis demonstrated that the isolates were strains of Burkholderia(5 strains), Pseudomonas (1 strain), Ralstonia (1 strain), and unidentified bacterium (1 strains). All PSB isolatesshowed the capability to dissolve Ca-P, and only 1 strain (Ralstonia strain) was able to dissolve Al-P in agar platemedium. The P-solubilization by these isolates was correlated with pH of medium. Inoculation of the bacterialstrains on clover on Al-toxic medium showed that all isolates increased the plant dry weight compared withuninoculated treatment. Our results showed that those PSB isolates have potential to be developed as a biofertilizerto increase the efficiency of P-inorganic fertilizer used in Al-toxic soils.
Digital Agency Start-up Strategy in Indonesia
Authors: Krisnanto Umbas , Febriana Anggi
Published: April 2018

This study aims to find an alternative strategy based on important factors to market and analize strategy for digital agency company. Based on IE matrix result, the agency is placed on quadrant I as growing and developing strategy. SWOT analysis that on quadrant IV, the agencyusing defensive strategy to control internal performance. The agency is expected to use competitive strategy because of SPACE results marked a line on competitive quadrant. There is a high value on TAS based on QSPM assessment. The agency suggested using market penetration strategy to maintain and increase market share, competitive price, advertising, and promotion.
The Editor’s Two Cents
Authors: Urban Greg
Published: April 2018

The Editor’s Two Cents
Using Boundary Objects to Facilitate Culture Change and Integrate a Global Top Management Team
Authors: Gluesing Julia C.
Published: April 2018

As business anthropologists, we are often called upon to work on organizational change initiatives as members of a change team.  This article is the story of one organizational change initiative involving a global top management team in a healthcare division of a large multinational firm and the research that was used as the basis for implementing change in the top management team and subsequently in the division as a whole.  Specifically, the article focuses on how the change team, of which I was a part, communicated the research results to the top management team and to employees of the company by presenting the results in a map that became a boundary object, that facilitating translation across diverse groups, joint sensemaking, and local action in the change process.
The Woes of Implementation Practice: Getting Caught by the “Program of the Month”
Authors: Briody Elizabeth K.
Published: April 2018

Senior leaders from a large American hospital told me that they wanted their hospital to become more “patient-centric” and asked me to help them.  I was hired to conduct an ethnographic study of the hospital with a team of six employees and the goal of improving patient experiences.  Sixteen months later, the research was completed, effective models of hospital work practices documented, recommendations made, and 16 tools developed to improve hospital culture.  Yet none of our work was implemented.  I returned to my field notes to discover clues that might explain why.  This article explains the process I followed, the stories that revealed unwanted messages, the transcripts that enabled sensemaking, and the program-of-the-month cycle that prevented implementation from occurring.
Cost-effectiveness of a New Opportunistic Screening Strategy for Walk-in Fingertip HbA1c Testing at Community Pharmacies in Japan
Authors: Shono Aiko , Kondo Masahide , Hoshi Shu-ling , Okubo Reiko , Yahagi Naoya
Published: April 2018

OBJECTIVE

A new opportunistic community-based strategy was launched in Japan in April 2014 to detect lifestyle-related diseases, including diabetes, by creating Specimen Measurement Offices (SMOs). SMOs offer walk-in fingertip HbA1c testing. This article aimed to assess the value-for-money of HbA1c testing services at SMOs by conducting a cost-effectiveness analysis.

RESEARCH DESIGN AND METHODS

We compared two scenarios: 1) status quo, defined as HbA1c testing that is available only through conventional screening, and 2) HbA1c testing available at SMOs as a complement to the status quo scenario. The model consisted of a screening module with a decision tree and a disease progression module with a Markov model. We calculated incremental cost-effectiveness ratios (i.e., cost per quality-adjusted life-years [QALYs]) over the lifetime analytic horizon as the primary end point of the cost-effectiveness analysis. In this model, we assumed the participant cohort to be people 40–74 years of age who sought walk-in fingertip HbA1c testing at SMOs on the premises of community pharmacies. Costs and outcomes were discounted at a rate of 3%. The cost-effectiveness was analyzed from a societal perspective.

RESULTS

The incremental cost per individual for those 40–74 years of age was estimated to be −527 U.S. dollars (USD) (−52,722 Japanese yen [JPY]) for HbA1c testing at SMOs compared with the status quo. Incremental effectiveness was estimated to be 0.0203 QALYs for HbA1c testing at SMOs compared with the status quo. Therefore, this cost-effectiveness analysis showed that compared with the status quo, HbA1c testing at SMOs was more effective and had lower cost for the population studied.

CONCLUSIONS

We consider our results to be robust because most simulations were under the threshold of USD 50,000 (JPY 5,000,000) per QALYs gained, by sensitivity analysis. These results will be useful to managers of pharmacies or other health institutions and/or policy makers in local government.
KREATIVITAS DAN INOVASI PELAKU KUBE
Authors: Sariningsih Yuce
Published: April 2018

This research concerning the program evaluation from Social Ministry of Republic of Indonesia which have conducted a productive economic activity in form of small business group, that is called Kelompok Usaha Bersama (KUBE) for the poor woman. It focused on reducing poverty in the context of building creativity and innovation as a main component of entrepreneurship. Another fact described that their welfare condition was in low level. The aim and purpose of this research was to analyze their creativity and innovation. The research has been conducted in West Java-Indonesia, and determined 111 (one hundred and eleven) respondents as sample. The research employed explanatory survey method and the data sources was primary and secondary data. A Questionnaire, observation and structured interview have been choosen for the data gathering techniques, and has been analyzed by path analysis. The research finding showed that respondent in condition lack of creativity and innovation and the recommendation has been formulated by improving the entrepreuneurial spirit of KUBE’s social advisor of KUBE.
ANALISIS ETIKA KERJA ISLAM, BUDAYA ORGANISASI, KOMITMEN ORGANISASI, DAN KOMPETENSI SUMBER DAYA MANUSIA TERHADAP KINERJA KARYAWAN (Studi Empiris pada Karyawan Perbankan Syariah di Indonesia)
Authors: Akob Muh.
Published: April 2018

Abstrak
Kerja Islam terhadap Komitmen Organisasi, dan juga menguji pengaruh Budaya Organisasi, Komitmen Organisasi  dan Kompetensi SDI terhadap Kinerja Karyawan, penelitian ini dilakukan pada karyawan di 6 Bank Umum Syariah di Indonesia (Makassar, Palembang dan Semarang). Untuk menjawab permasalah penelitian dikembangkan sebuah model penelitian empiris, terdiri dari 5 konstruk dan 23 indikator. Dari lima variabel tersebut dirumuskan lima hipotesis penelitian. Pengumpulan data dilakukan melalui kuesioner yang disampaikan secara langsung maupun melalui surat serta contact person. Kuesioner dikirim sebanyak 250 dan setelah melalui proses editing hanya sebanyak 219 kuesioner yang dinyatakan valid. Teknik Analisis yang digunakan adalah Structural Equation Modelling (SEM) dengan software LISREL v.8.54. Hasil pengujian hipotesis menunjukkan bahwa; Variabel Komitmen Organisasi di-pengaruhi secara signifikans oleh variabel bebas Etika Kerja Islami dengan nilai korelasi 0,27; nilai t-hitung yang diperoleh sebesar 3,18. Variabel Kinerja Karyawan tidak dipengaruhi secara signifikan oleh variable Etika Kerja Islam dengan nilai korelasi 0,09, nilai t-hitung sebesar 1,39. Variabel Kinerja Karyawan dipengaruhi secara signifikan oleh variabel bebas Budaya Organisasi dengan nilai korelasi 0,36; nilai t-hitung yang diperoleh sebesar 6,48. Variabel Kinerja Karyawan dipengaruhi secara signifikan oleh variabel bebas Kompetensi SDM dengan nilai korelasi sebesar 0,19. Nilai t-hitung yang diperoleh sebesar 3,29. Variabel Kinerja Karyawan juga dipengaruhi secara signifikans oleh variabel bebas Komitmen Organisasi dengan nilai korelasi 0,63. Nilai T-Value yang diperoleh untuk variabel bebas ini lebih besar dari 1,96, yaitu 8,41.
La empatía como metodología. Una receta contra el exotismo
Authors: Salmon Perrilliat Esteban
Published: April 2018

La etnografía depende como ninguna otra ciencia social de la inmersión total del investigador en sociedades que no conoce; requiere vivir como otra persona, utilizar la empatía como método de aprendizaje y el cuerpo como herramienta de conocimiento.
Antropología, memoria e historia
Authors: Bensa Alban
Published: April 2018

Este texto retoma y prolonga las propuestas metodológicas y teóricas que desarrollé en dos libros, Después de Lévi-Strauss y El fin del exotismo, recientemente publicados en español
El fin del exotismo y sus tramas disciplinarias
Authors: Arrioja Díaz-Viruell Luis Alberto
Published: April 2018

Este texto es una revisión panorámica de Alban Bensa, El fin del exotismo. Ensayos de antropología crítica, México, El Colegio de Michoacán / Secretaría de Cultura, 2016, 271 pp., ISBN: 978-607-9470-44-9
“De la tristeza del historiador” a la Apología para la historia y al Oficio de historiar (1939-1949-1988)
Authors: Calvo Thomas
Published: April 2018

Reflexión sobre la obra de Luis González y la historiografía francesa.
A DESAPROPRIAÇÃO JUDICIAL (§§ 4º E 5º DO ART. 1228 DO CÓDIGO CIVIL): GARANTIA DO DIREITO À MORADIA, DA FUNÇÃO SOCIAL DA PROPRIEDADE E INSTRUMENTO DE IMPLEMENTAÇÃO DA POLÍTICA URBANA E DE REFORMA AGRÁRIA.
Authors: Nakamura Andre Luiz dos Santos
Published: April 2018

Este artigo pretende abordar a desapropriação judicial, introduzida no ordenamento jurídico positivo pelos §§ 4º e 5º do Código Civil. Tratar-se-á dos requisitos para a aplicabilidade do instituto e da responsabilidade pelo pagamento da indenização. Por fim, será estabelecido como a desapropriação judicial pode ser uma ferramenta de política pública urbana e de reforma agrária.
DIREITO PRIVADO E RELAÇÕES SOCIAIS: UMA BREVE ANÁLISE DO TRANSEXUALISMO NO BRASIL
Authors: De Holanda Fábio Campelo Conrado
Published: April 2018

O presente artigo promove o debate acerca de tema considerado atual no cenário constitucional e civilista brasileiro, consistente no tratamento jurídico dado aos transexuais em casos de intervenção cirúrgica específica, bem como seus efeitos no registro civil, por meio de uma discussão teórica com ênfase nos aspectos constitucionais da dignidade humana, proteção das minorias e identidade de gênero, bem como seus reflexos infraconstitucionais nos direitos da personalidade, cujo tratamento na esfera privada mereceu destaque no vigente Código Civil. Destacou-se que tais proposições bioéticas merecem a reflexão da sociedade sobre em que medida tal violência simbólica atenta contra a dignidade das minorias sob enfoque, de modo a contemplar as variadas formas de vivência e convivência na esfera privada.
A BRIEF ANALYSIS OF THE LEGAL FRAMEWORK FOR METHYL BROMIDE
Authors: Da Cunha Soares Júnior Wolney
Published: April 2018

Many international conventions have been celebrated recently in an attempt to avoid or reduce the problems arising from advances in science and technology. In this context, in order to protect the environment, emerged the Vienna Convention for the Protection of the Ozone Layer (1985) and the Montreal Protocol on Substances that Deplete the Ozone Layer (1987), which provide control mechanisms for the production and consumption, for example, of methyl bromide, one of the most aggressive substances for the ozone layer in the world. However, article 2H, paragraph 6, of the Montreal Protocol brings exemptions for the abovementioned gas, which can be freely used for the exclusively purpose of quarantine and pre-shipment of goods for import and export in the international market. Nevertheless, through the Joint Instruction (Instrução Normativa Conjunta – INC) SDA/ANVISA/IBAMA nº 01/2002, Brazil edited rules more severe than the prohibitions prescribed by the Montreal Protocol and banned any use of methyl bromide after 31/12/2015, including the phytosanitary treatment. Considering the potential costs of this restriction for the public health and the Brazilian economy, recently it has been edited the Joint Instruction (Instrução Normativa Conjunta – INC) SDA/ANVISA/IBAMA nº 02/2015 simply to abrogate the previous norm for the sake of the referred exemptions. Thus, there is no violation of any international obligation assumed by Brazil.
DO INSTITUTO DO MICROEMPREENDEDOR INDIVIDUAL NO DIREITO BRASILEIRO: CONCEITO, NATUREZA E REGIME JURÍDICO.
Authors: Oliveira George Felicio Gomes de , Oliveira George Felício Gomes de
Published: April 2018

A essência do desenvolvimento é a melhoria da qualidade de vida das pessoas menos favorecidas. O combate à pobreza e o respeito à dignidade humana são estratégias aptas a alterar a realidade. Para tanto, é recomendável que a noção de desenvolvimento seja desatrelada do estrito espaço da economia e amplie seu horizonte em atenção à liberdade do ser humano. Se, por um lado, livre é aquele que pode se movimentar sem obstáculos abusivos ao exercício de seus direitos, do outro lado mira-se a face da liberdade segundo a qual ao sujeito estão disponíveis os instrumentos necessários ao pleno desempenho de suas capacidades. Argumenta-se que, no Brasil, tais meios sempre estiveram longe do alcance da maioria da população. Investiga-se, no presente estudo, uma iniciativa que almeja influenciar a alteração desse cenário: o Programa do Microempreendedor Individual. Estabelecido a partir da Lei Complementar nº 128/2008, referido instituto jurídico possibilita que determinadas categorias de trabalhadores informais legalizem-se como pequenos empresários, tornando-se, assim, acolhidos por uma política pública estatal. Examina-se os alicerces dessa estrutura, buscando, primordialmente, delinear-lhe o regime jurídico. Além disso, pretende-se demonstrar que há razões para acreditar no acerto dessa empreitada em prol do desenvolvimento de uma cidadania empresarial livre da burocracia historicamente excludente. Mediante pesquisa de caráter interdisciplinar, através de metodologia de abordagem qualitativa e pura, além de exploratória quanto aos objetivos e bibliográfica e documental quanto às fontes, verifica-se o impacto dessa medida no ordenamento jurídico brasileiro, no sistema econômico e no cotidiano das pessoas sob seu manto acolhidos.
TERCEIRIZAÇÃO NO SERVIÇO PÚBLICO E A PRECARIZAÇÃO DOS DIREITOS TRABALHISTAS
Authors: COSTA ANDREA DOURADO , GOMES ANA VIRGÍNIA MOREIRA
Published: April 2018

O estudo tem como objetivo discutir o uso da terceirização pela Administração Pública no Brasil, tendo como paradigma normas nacionais e internacionais de proteção ao trabalho. A pesquisa examina a prática da terceirização, apresentando sua definição, objetivos, forma de aplicação, aspectos normativos, especialmente àqueles mais relevantes no setor público, bem como analisa jurisprudência referente à terceirização nos setores privado e público. Serão analisados dados coletados, através de um estudo realizado pela CUT, sobre o alto índice de acidentes de trabalhadores terceirizados para demonstrar a precarização causada por essa prática. Busca-se, também, verificar a aplicação das normas internacionais existentes sobre o tema. Apesar da inexistência de norma internacional específica sobre o tema, a Organização Internacional do Trabalho adotou a Convenção no 94, ratificada pelo Brasil, que possui regras aplicáveis à questão da terceirização. Ademais, o estudo propõe a necessidade de respeito ao princípio da não discriminação diante da desigualdade de salários para funções idênticas entre trabalhadores terceirizados e efetivos, de proteção à saúde dos trabalhadores e de outros direitos e garantias constitucionalmente asseguradas, conforme a Convenção nº 111 da OIT, também ratificada pelo Brasil. Por fim, reitera-se a necessidade de conferir uma adequada proteção aos direitos fundamentais relacionados ao trabalho terceirizado, através de uma legislação específica e clara para garantir proteção aos direitos constitucionais dos trabalhadores. No artigo, foi realizada uma pesquisa bibliográfica e exploratória, embasada, principalmente, em livros, artigos científicos e normas nacionais e internacionais.
THE ROLE OF PRECEDENTS AS A FILTER FOR ARGUMENTATION
Authors: Perrone Campos Mello Patrícia
Published: April 2018

This essay examines the role and the limits of a theory of precedent in promoting the values of legal certainty, equality, legitimacy, and efficiency of the courts. It demonstrates, further, that precedents have another major role: they serve as a filter for legal argumentation, guiding litigants and judges on the issues to be discussed and considered in the decision of a case. With this objective, section I clarifies the relationship between the use of precedents and the values mentioned above. Section II demonstrates the manner in which precedents are applied. Section III analyses the subjective and institutional elements that also influence judicial behavior. Finally, section IV presents the conclusion, highlighting the importance of precedents for legal reasoning.
TUTELA ANTICIPATORIA DI URGENZA E SUA STABILIZZAZIONE NEL NUOVO C.P.C. BRASILIANO: COMPARAZIONE CON IL SISTEMA FRANCESE E CON QUELLO ITALIANO
Authors: Bonato Giovanni
Published: April 2018

O presente trabalho tem por objeto a tutela antecipada de urgência no Novo Código de Processo Civil brasileiro. O Autor conduz uma investigação de direito comparado em relação aos sistemas jurídicos do Brasil, da França e da Itália. Após ter abordado os référés no ordenamento francês e os provimentos cautelares a instrumentalidade atenuada no ordenamento italiano, o Autor trata da tutela provisória no novo CPC brasileiro, do procedimento da tutela antecipada requerida em caráter antecedente e da dinamica da estabilização e definitividade da decisão do art. 304. Por fim, o Autor faz uma analise das três teorias cunhadas pela doutrina brasileira no que diz respeito à tecnica da estabilização da tutela antecipada de urgência.
O PRINCÍPIO DO EQUILÍBRIO ECONÔMICO E FINANCEIRO NO REGIME GERAL DE PREVIDÊNCIA SOCIAL
Authors: Guedes Luciano Palhano
Published: April 2018

Este artigo pretende analisar o princípio do equilíbrio financeiro e atuarial do Regime Geral de Previdência Social. Para tanto, buscou-se analisar o conceito de equilíbrio financeiro e atuarial, sua inserção no texto constitucional e a sua relação com a ideia de reserva do possível e com o princípio da solidariedade. Por fim, discute-se a problemática do déficit da previdência, com indicação de diversas opiniões acerca da matéria, com destaque para a questão da Previdência Rural, tida como causa maior do desequilíbrio das contas da previdência. Concluiu-se pela legitimidade de reformas que reduzam a proteção previdenciária, desde que não haja outras alternativas e seja respeitado o conteúdo essencial do direito à previdência social.
OS CONTORNOS OBJETIVOS DA PROIBIÇÃO DE CONTRATAR COM O PODER PÚBLICO POR IMPROBIDADE ADMINISTRATIVA.
Authors: Accioly Teixeira João Pedro
Published: April 2018

O escopo desta pesquisa, como possibilita inferir o título outorgado ao trabalho, é delimitar o alcance da proibição de contratar com o Poder Público – enquanto sanção aplicável, nos termos do art. 12, da Lei 8.429/92, aos atos de improbidade administrativa. Nesse sentido, espera-se elucidar questões de pouca elaboração ou intensa controvérsia doutrinária e jurisprudencial, com vistas a repelir excessos e corrigir atecnicidades no manejo da medida proibitiva – promovendo, assim, a segurança das relações jurídicas, a preservação das empresas e a proporcionalidade das reprimendas impostas pelo Estado.
O GIRO INSTITUCIONAL E A ABORDAGEM DAS CAPACIDADES NA ANÁLISE DA (IN) CONSTITUCIONALIDADE SUPERVENIENTE DO ART. 1º DA LC Nº 110/01
Authors: Meira Renan Sales de
Published: April 2018

A Lei Complementar nº 110/01 instituiu no ordenamento jurídico nacional dois tributos, dos quais um, na visão do Supremo Tribunal Federal (STF), seria uma contribuição social – tributo finalístico, portanto. No Recurso Extraordinário nº 878.313, está posta a discussão da tese da inconstitucionalidade superveniente da exação referida, sob o fundamento de que se teria cessado a finalidade para a qual fora instituído do tributo em comento. À luz da abordagem das capacidades institucionais, defende-se que a solução correta a ser adotada pelo STF seria a posição de deferência ao Poder Legislativo, posto que em pior condição institucional para analisar a questão (verificação da necessidade de permanência do tributo) se comparado ao Congresso Nacional. Isso não significa, entretanto, ruptura com o princípio da supremacia constitucional, posto que esse não se confunde com a ideia de supremacia judicial.
CONSTITUIÇÃO PROCESSUAL: ÉTICA DE ALTERIDADE, DEMOCRACIA E DIVERSIDADE NAS CONVERSAÇÕES CONSTITUCIONAIS
Authors: Araújo Mayara de Carvalho , Cruz Gabriel Soares
Published: April 2018

Objetiva-se entender como a Constituição do Brasil de 1988 compreende e insere as diversidades dentro da linguagem constitucional. Afirma-se que o discurso constitucional deve ser construído sobre bases dialógicas permanentes. São os seres humanos que criam a constituição e não o contrário. Os consensos, quando atingidos, precisam ser provisórios e construídos a partir do processo de formação histórico-social de um Estado. Ao reconhecer, o Estado e o Direito exercem o poder de incluir, o que também lhes confere a faculdade de excluir. A lógica do reconhecimento continua dizendo mais sobre a concentração de poder de maiorias qualitativas do que propriamente sobre o novo lugar conferido aos outrora excluídos. Assim, faz-se necessária uma constituição processual como meio e materialização das diversidades e transformação das realidades das minorias qualitativas.
Sources of Communication that Help Facilitate Effective Understanding of Diabetes Health-Care: A Case at Stanger Hospital's Diabetes Clinic
Authors: Moola Sabihah
Published: April 2018

Effective health communication is a core requirement to help facilitate effective understanding of disease and illness. This paper reports on a study conducted at Stanger Hospitalâ€™s diabetes clinic in KwaZulu-Natal, South Africa to explore the sources of communication that assist patients in understanding diabetes as an illness. A qualitative case-study methodology was used consisting of in-depth interviews, observation, and documentation. Persuasive behaviour change communication in respect of diabetes care was analysed as it related to the relationship between the health-care professional (HCP) and the patient. The Elaboration Likelihood Model (ELM), which had been developed to understand how messages sent from the sender (HCP, media sources) could have either a positive or a negative impact (attitude change) on the receiver, was used to analyse and interpret the data obtained from patients. Results indicated that in order to facilitate effective health-care, literacy aspects were important in health-care and that HCPs needed to ensure that patients understood the different sources of communication.