bluuebunny/crossref_metadata_2025 huggingface dataset:
NEUROLOGICAL ABNORMALITIES IN CHILDREN WITH TYPE 1 DIABETES MELLITUS
Authors: Jangir Rakesh , SENGAR GS  , TUSHAR DWIVEDI  , NISHANT ASWANI
Published: September 2023

Objective: The objective of the study is to find out the prevalence of neurological abnormalities in children between 5 and 15 years with type-1 diabetes mellitus (T1DM) of at least 2 years duration and the risk factors associated with the development of neurological abnormalities.
Methods: Hospital-based cross-sectional study on 150 Children of 5–15 years of age having type I diabetes of at least 2 years’ duration by simple random sampling fulfilling the inclusion criteria, at Department of Pediatric Medicine, Sardar Patel Medical College and P.B.M. Hospital Bikaner.
Results: Mean age was 10.9±3.6 years, male to female ratio was 1.63:1. The prevalence of peripheral neuropathy was 42.3% when 1 abnormal attribute in at least 1 nerve was considered, it was 7.3% when 2 abnormal attributes in 2 nerves were considered, 4.6% had autonomic neuropathy and 4% had cognitive abnormalities. The peripheral neuropathy was subclinical in a substantial number of cases as up to 39.4% and 39.3% of T1DM cases having peripheral neuropathy had normal neuropathic symptom score and neuropathic disability score, respectively. Female with longer duration of diabetes, higher mean age of diagnosis, and higher mean HbA1c level were significantly more likely to develop peripheral neuropathy.
Conclusion: Neurological complications begin quite early and insidiously in T1DM patients highlighting the importance of early and regular screening by nerve conduction study.
EFFECTIVENESS OF BALLOON-BLOWING EXERCISE ON RESPIRATORY PARAMETERS AMONG CHILDREN WITH LOWER RESPIRATORY TRACT INFECTION
Authors: JISS MARY JAMES  , LEANA PHEBE WILSON S
Published: September 2023

Objective: This study was conducted to assess the effectiveness of balloon-blowing exercise on respiratory parameters among children with lower respiratory tract infection.
Methods: A quantitative research approach and quasi-experimental (two-group pretest–posttest design) were adopted for this study. The sample size was 40 children with lower respiratory tract infection and used non-probability convenience sampling technique.
Results: The results showed that the mean posttest score of respiratory parameters was 31 of the experimental group who were administered balloon blowing exercise with routine care which was higher than the control group posttest mean score of 23.35 having routine care and the t value was 4.21 (p<0.001) which showed that there was a significant difference in the post-test score of respiratory parameters in control and experimental groups.
Conclusion: The study concluded that balloon-blowing exercise was effective to improve the respiratory parameters among children with lower respiratory tract infection.
ESTIMATION OF PREVALENCE OF HEPATITIS C VIRUS INFECTION BY SEROLOGICAL TEST AND REAL TIME RT-PCR TEST AMONG SUSPECTED VIRAL HEPATITIS CASES ATTENDING TERTIARY CARE HOSPITAL, KOLKATA
Authors: ASIS KUMAR GHOSH  , RAJA RAY  , KALIDAS RIT  , BIPASA CHAKRABORTY  , MAHIUDDIN AHAMMED
Published: September 2023

Objective: Hepatitis C virus (HCV) infection is a major public health problem in India and worldwide. Majority remain asymptomatic until they develop serious complications like liver cirrhosis or hepatocellular carcinoma with fatal outcome. Hence, early diagnosis of active HCV infection and prompt initiation of treatment is important. Treatment with directly acting antivirals (DAAs) resulted in high sustained virological response (SVR) rates of >95% globally. This study was done to estimate seroprevalence and prevalence of active HCV infection among study population. After initiation of treatment, SVR rates were estimated.
Methods: This was hospital-based, cross-sectional, and observational study. Screening was done by third-generation Enzyme-linked immunosorbent assay to detect anti-HCV antibody, then confirmatory real-time reverse transcription-polymerase chain reaction (RT-PCR) test was done for detection of active cases and determining their viral load. Treatment of 12-week duration was initiated by DAAs and followed up to estimate SVR by doing real-time RT-PCR after 12 weeks of treatment completion.
Result: Among 17,752 consecutive non-repetitive blood samples, seroprevalence was 1.78%. The prevalence of active cases was 1.52%. HCV active infection was prevalent more among male (64.21%) and among 40–60 years age group. History of multiple blood transfusion (58%) was the most common risk factor, followed by multiple sex partners (13.3%). Coinfections with Hepatitis B virus and Human immunodeficiency virus were seen in 13.65% of cases. About 92% of patients completed their treatment. SVR was 97.87%.
Conclusion: High SVR of 97.87% is evidence-based data that support that proper treatment can eliminate HCV infection. Detection by real-time RT-PCR and highly effective DAA has made a paradigm shift to approach of HCV diagnosis and management in recent times
GAMMA GLUTAMYL TRANSFERASE LEVELS IN PATIENTS WITH ACUTE STROKE: AN ANALYTICAL STUDY
Authors: DOONGAR SINGH  , SUJATA AGARWAL  , PRADEEP MITTAL  , SHASHI BHUSHAN SHARMA
Published: September 2023

Objectives: Stroke is a significant global health issue with a major socioeconomic burden, ranking as the second leading cause of death worldwide. While stroke rates have declined in high-income countries, they have increased in low- to middle-income countries, including India. The World Health Organization defines stroke as a disturbance of cerebral function caused by vascular factors, classified as ischemic or hemorrhagic.
Methods: Ischemic stroke is primarily caused by atherosclerosis in the brain’s arteries, including the proximal aorta, leading to embolus formation. Other factors contributing to stroke include arterial stenosis, coexisting thrombosis, artery-to-artery embolism, micro atheroma, lipohyalinosis, and occlusive diseases of small brain arteries. Cardiogenic embolism, often associated with atrial fibrillation, contributes to a significant proportion of ischemic strokes. Gamma-glutamyl transferase (GGT), commonly used as a marker for alcohol consumption and liver diseases, is also linked to oxidative stress, inflammation, and atherosclerosis. Elevated GGT levels are associated with various stroke risk factors.
Results: GGT plays a crucial role in cellular intake of glutathione, an important antioxidant. Paradoxically, it can generate reactive oxygen species in the presence of certain metals. Studies have found a correlation between high serum GGT levels and stroke risk, potentially due to oxidative stress and atherosclerosis progression.
Conclusion: Despite its primary use as an alcohol consumption marker, GGT has emerged as a potential independent biomarker for vascular diseases, including stroke. However, limited research exists on the association between GGT and acute stroke. This study aims to evaluate GGT levels in patients with acute stroke, exploring potential differences among stroke types to better understand the impact of GGT on acute stroke.
Modelo actancial del nexo agua-alimentos-comercio internacional
Authors: Mujica Trejo Bettsy Esmeralda , Sánchez Torres Yolanda , Terrones Cordero Aníbal , Cruz Cruz Mario
Published: September 2023

Objetivo: proporcionar un marco conceptual de la esquematización del nexo agua-alimentos-comercio internacional utilizando el modelo actancial, basado en el análisis cualitativo de las relaciones que se presentan entre sus participantes con un enfoque integrador. Diseño metodológico: se explica bajo la lógica del modelo actancial centrado en la descripción y clasificación de personajes, o bien, llamados actantes. El análisis se basó en la revisión de artículos que exponen el contexto y debate de los elementos del modelo actancial, que permitieran identificar las principales características que explican al actante y sus interrelaciones a través de la esquematización en el nexo de estudio. Resultados: permiten comprender de manera esquemática y cualitativa las relaciones que subyacen entre los elementos que componen el nexo agua-alimentos-comercio internacional con una visión novedosa, argumentando el rol que desempeñan cada uno de los componentes de los actantes y los ejes del nexo. Esto es relevante debido a que la comercialización de agua virtual, puede conducir a serios problemas de dependencia hidro-alimentaria, por lo que se necesita de la formulación de políticas públicas estratégicas y efectivas en el corto y largo plazo. Limitaciones de la investigación: se sugiere complementar esta investigación con un análisis cuantitativo bajo una perspectiva de la complejidad de redes que pueda valorar los efectos de estas interrelaciones desde una postura teórica y práctica e incorporar otros agentes que determinan la política hídrica y comercial de manera estratégica hacia una menor dependencia hidro-alimentaria. Hallazgos: estas interrelaciones son diversas e intensivas, destacando la importancia y compresión del nexo a escala global y nacional.
Recent Advances in Cochlear Implant: A Systematic Review
Authors: Jacob Ms. Jiya Annu , Kumaraswamy Dr. Satish
Published: September 2023

Abstract: Background: Cochlear implants are implantable device designed to mimic the function of a healthy inner ear. They replace the function of damaged sensory hair cells inside the inner ear to help provide clearer sound than what hearing aids can provide. The patients with cochlear implants benefit from cutting-edge sound processing technology that analyses the surrounding noise and automatically modifies the processors settings for optimum hearing. Advances in the programming of sound processing algorithm have improved the user’s abilities to hear sounds other than speech such as music. This systematic review aims to provide knowledge about the recent advances in cochlear implant instrumentation and mapping strategies. Methods: A comprehensive literature search was conducted across major electronic databases, including PubMed, Google Scholar, Science Direct, ProQuest and Psynet. Studies published between 2012 to 2023 were included if they focused on latest technologies on cochlear implant in terms of instrumentation and mapping strategies. Relevant articles were selected, and their quality was assessed using with Preferred reporting Items for Systematic review and Meta-Analysis (PRISMA).
Accountability And Internal Control Systems On The Quality Of Regional Equipment Organizational Reports With Organizational Commitment As Moderation
Authors: Saputra Bagaskara Aji , Gunawan Barbara
Published: September 2023

Purpose: This study aims to examine the effect of accountability and internal control systems on thequalityof financial reports of regional apparatus organizations with organizational commitment as moderation. Methodology/approach: Collecting data in this study using a questionnaire. Questionnaires were distributed as many as 120 questionnaires which were distributed to 20 OPD in Bantul Regency. A total of 95 questionnaires were filled out and returned to the authors for analysis. This research is included into quantitative research. The sample in this study used purposive sampling. The analytical tool used in this study is multiple linear regression with the IBM SPSS Statistics 22 application. Findings: The results of this study indicate that accountability has a positive and significant effect on the quality of financial statements of local government organizations, the internal control system has a positive effect on the quality of financial reports and the internal control system has a positive and significant effect on the quality of financial reports and is moderated by organizational commitment. Practical implications: Future will improve accountability performance of a government agency so that the government can provide information to the public in the form of quality financial reports. Originality/value: Accountability has a role to describe the success or failure of an organization's mission to achieve predetermined goals and indicators in the form of local government financial reports.
Association between regular breakfast consumption and academic performance among 6th-grade elementary school male students in Makkah, Saudi Arabia
Authors: Alruwaili Fahad Khulaif , Khan Adeel Ahmed , Alruwaili Amal , Alruwaili Wardah , Alruwaili Fahdah
Published: September 2023

Objectives: To determine the association between regular breakfast consumption and academic performance among 6th-grade elementary school male students in Makkah, Saudi Arabia.

Methods: Our cross-sectional study used a questionnaire for public and private elementary school children in Makkah, Saudi Arabia. Participants with known mental retardation, language barriers, and chronic diseases were excluded. The data analysis was performed using IBM SPSS V.26.

Results: In our study, 412 students were included. Most students (74.3%) obtained a high final degree between 80 - 100%. Most students (67.2%) believed having breakfast helps in obtaining high degrees. In addition, those who never had breakfast had a lower academic degree (p-value <0.001).

Conclusion: The results of our study emphasized the significance of having breakfast on a daily basis for academic success, as students who reported consuming breakfast regularly were found to be more likely to achieve high academic scores.
Targeting the Carbonic Anhydrase Enzyme with Synthesized Benzenesulfonamide Derivatives: Inhibiting Tumor Growth
Authors: Kifah Abbas Zainab , Naser Noor H. , Atiya Rana Neama
Published: September 2023

Objectives: To assess the anticancer effects of recently developed compounds, Sa, Sb, Sc, and Sd. These compounds were designed to specifically target the carbonic anhydrase enzyme in solid tumors.

 Methods: The chemical synthesis involved the use of sulfanilamide, chloroacetyl chloride, GABA, thionyl chloride, methanol, hydrazine hydrate, potassium hydroxide, carbon disulfide, and benzyl chloride derivatives. Docking studies were conducted using the MOE software program version 2015.10, and cytotoxic activity was predicted using the MTT assay.

Results: The newly synthesized compounds exhibited notable antineoplastic activity in both in silico and cell line investigations. Although they showed a significant difference in potency compared to cisplatin against cancer cells, they also demonstrated significant differences in toxicity towards normal cells. When compared to acetazolamide, compounds Sb displayed an IC50 = 28.41 μM, which was significantly different, and compound Sd showed a non-significant difference with an IC50 = 61.20 μM against MCF7 cells. Additionally, Sb and Sd demonstrated significant difference in toxicity, with IC50 = 279.02 μM and 194.00 μM, respectively, against MCF10a cells. These findings indicate a significant difference compared to acetazolamide for the Sb compound and suggest that the synthesized compounds hold potential for further development as antineoplastic agents. Furthermore, the results from the cell line study align with the in silico study, where both compounds Sb and Sd exhibited higher S scores compared to acetazolamide, implying a stronger binding affinity with the receptor's catalytic site. The presence of a substituted 1,2,4-triazole ring in these compounds contributed to enhanced flexibility and improved interaction with the receptor.

Conclusion: A new synthesized compounds exhibited cytotoxicity and demonstrated inhibitory potencies against carbonic anhydrase.
Moxifloxacin's Therapeutic Effects in AA-Induced Colitis: Anti-Inflammatory Action through NF-κB Pathway Inhibition, Including TNF-α Pathway and Downstream Inflammatory Processes
Authors: Dawood Jaffar O. , Abu-Raghif Ahmed
Published: September 2023

Objectives: The aim of the present study was to evaluate possible therapeutic effects of moxifloxacin against acetic acid-induced colitis in a rat model.

Methods: Forty adult Wistar rats were separated into 4 groups, including the negative control group, acetic acid (AA) group, AA + sulfasalazine (100 mg/kg/day) group, and AA+ moxifloxacin (MFX) (8 mg/kg/day) group. Experimental colitis was induced in rats by rectal administration of (4%v/v) acetic acid. Rats with colitis were received either MFX 8mg/kg/day or sulfasalazine 100mg/kg orally for 7days.The parameters measured are macroscopical assessment, colon weight (indicator of edema) and the measurement of concentrations of the proinflammatory cytokine TNF-α, oxidative stress marker malondialdehyde (MDA), adhesion molecule selectin and the inflammatory mediator NF-κB in colonic tissue homogenate.

Results: This study had shown that AA elevate macroscopical scores, colon weight and biochemical homogenate parameters and all measured parameters were significantly reduced by both moxifloxacin and sulfasalazine with nonsignificant difference between them.

Conclusions: The study explain that moxifloxacin possesses therapeutic potential in in AA induced colitis and its anti-inflammatory actions may involve inhibition of NF-κB inflammatory pathways including TNF-α pathway with its downstream inflammatory process such as elevation of adhesion molecule synthesis and oxidative species overproduction in the colonic tissues.
Nomenclature of Aushadh Sevan Kaal(Time of Drug Administration) In Various Ayurved Samhita’s and Its Commentaries- A Critical Review
Authors: S. Borkar Dr. Preeti , Yanpallewar Dr.Sushil , Pal Singh Dr.Pratyendra , Pargaonkar Dr. Akshay , Thakre Dr.Rhushikesh
Published: September 2023

Aushadh Sevan Kaal is a concept described in Ayurved samhitas, which means the time of medicine administration.Kaal(Time) isincluded in karana dravya and plays many important roles in our lives. The existence of the Kaal is from the Shrishti Uttpatti.Aacharya charak hasdescribed Trisutra Ayurved, which explains the knowledge about the entire Ayurveda.Trisutra includes Hetu[causative factors], Linga[signs andsymptoms], and Aushadh [medicines]. Additional considerations listed by Acharya Charaka include the patient's desha (region), kala (time),pramana (dosage), satmya (wholesomeness), asatmya (unwholesomeness), aahara (diet), and aushadh (medicine). Kaal is a particular and distinctcause of all kinds of outcomes and is also inevitable. Ayurveda is the science of life, emphasizing the idea of kaal as it is one of the karan dravya.The present study aims to critically analyze different terms used in samhitas for nomenclature and terminologies related to the administration time(aushadh sevan kaal) of ayurvedic herbo mineral formulations. To achieve this, we aim to study the concept of aushadha sevan kaal in varioussamhitas for its utility in identifying textual study material for selecting the treatment protocol. There are differences in the nomenclature[terminologies] in various samhitas and their commentaries. Mild variation is also observed in the number of types of Aushadh sevan kaal as perSamhitas. All Ayurveda treatments concentrate on maintaining and retaining the power of agni because it is the primary factor in establishing theDhatu Samyata.In the current era, it is observed that proper medicine administration needs to be done in relationship with Dosha,dusya,rogi, androgbala in consideration of the aushadh seven kaal. Hence, treatment is not successful in treating the patients.In this study, it is observed thatdifferent terms are mentioned in Ayurveda texts for different types of Aushadh sevan Kaal by different-different Acharyas.
ANALISIS GAYA BAHASA SINDIRAN DALAM VIDEO TIKTOK RIAN FAHARDHI
Authors: Mulyanto Agus , Probowati Andarini Rani , Purnamasari Ratih
Published: September 2023

The existence of social media such as TikTok opens up opportunities for people to express themselves freely. This freedom demands creativity in expression, among others by using a sarcastic language style. This study aims to examine the use of satire language style used by Tiktoker Rian Fahardhi in his video using Keraf's Language Style theory. This research uses descriptive research to describe the sarcastic language style used by Rian Fahardhi in TikTok videos. The data collection technique used is the listening method with note taking technique. The data analysis technique used in this research is content analysis technique. The results showed that Rian Fahardhi used 19 satire language styles consisting of 4 irony language styles, 6 cynicism language styles, and 9 sarcasm language styles. Satire is not only used to convey criticism and aspirations, but it can also be implemented for readers and listeners of language in various types of literary works and outside literature. By using satire, readers or listeners can pay attention to the words used more carefully in writing or speech. So that it can increase understanding and appreciation of the beauty of language and can strengthen the message to be conveyed.
Ragam Bahasa Bias Gender pada Pemberitaan Aktris Pascacerai
Authors: Moon Yuliana Jetia , Nesi Antonius , Yuliantari Ans Prawati
Published: September 2023

Bahasa dapat melanggengkan bias gender. Formulasi bahasa di dalam pemberitaan media turut memperkukuh, melestarikan, bahkan memperburuk ketidakadilan terhadap perempuan dalam masyarakat, tidak terkecuali para aktris. Tujuan penelitian ini adalah menemukan ragam bahasa bias gender pada pemberitaan aktris pascacerai. Penelitian ini termasuk telaah deskriptif kualitatif. Sumber data penelitian ini adalah media pemberitaan yang dibatasi hanya pada pemberitaan tentang aktris pascacerai. Data yang diambil berupa judul dan isi berita yang bias gender. Dalam pengumpulan data digunakan metode simak-baca, ditunjang dengan teknik ortografis. Selanjutnya, data dianalisis menggunakan analisis tekstual. Hasil penelitian ini menunjukkan bahwa masih terdapat media yang menempatkan aktris yang telah bercerai sebagai objek berita yang seksis dan bias gender. Ragam bahasa bias gender tampak dalam wujud diksi, frasa, dan kalimat. Wujud-wujud ragam bahasa tersebut dapat menempatkan posisi perempuan sebagai objek seksual, seperti ragam metafora yang merujuk pada tubuh perempuan, diksi dan kalimat yang menunjuk pada makna bahwa penyebab keretakan rumah tangga adalah perempuan, serta ragam bahasa dalam bentuk pelabelan terhadap perempuan atau stigmatisasi.Â Language can perpetuate gender bias. Formulation of language in media coverage helps strengthen, soothe, and even hurt the injustices against women in society, including actresses. The purpose of this research is to find a variety of gender bias language in the reporting of post-divorce actresses. This research includes a qualitative descriptive study. The data source for this research is media coverage which is limited to news about post-divorce actresses. The data taken is in the form of gender biased news titles and contents. In collecting data using the read-read method, supported by orthographic techniques. Furthermore, the data were analyzed using textual analysis. The results of this study indicate that there are still media that place divorced actresses as news objects that are sexy and gender biased. The variety of language gender bias appears in the form of diction, phrases and sentences. These various forms of language can position women as sexual objects, such as various metaphors that refer to women's bodies, diction and sentences that point to the meaning that women are the cause of household breakdown, as well as various languages in the form of labeling women or stigmatization
A linha de fuga e a identificação do leitor em narrativas ficcionais
Authors:   , Silva Diana Vieira da
Published: September 2023

A literatura como modo de pensar o indivíduo, seja dentro ou fora da narrativa, é um dos caminhos pelo qual este trabalho busca amparar-se. Deseja-se, portanto, compreender o papel das obras de ficção na identificação do leitor com base nos elementos textuais e diegéticos que as compõem. Fundamenta-se, para tanto, na filosofia de Gilles Deleuze e de seu conceito sobre a linha de fuga como instrumento na observação desse processo. Esta pesquisa baseia-se na revisão bibliográfica de abordagem qualitativa com tipo de delineamento “revisão de literatura” e está fundamentada teórico-metodologicamente em uma perspectiva dialógica (BRAIT, 2006) para analisar os elementos discursivos e subjetivos da narrativa de ficção. Pretende-se, como efeito deste projeto, delinear quais e como os recursos narrativos figuram-se na identificação do leitor e, assim, entender como o objeto textual concede ao homem o entendimento e a construção de seus saberes.
Constituição do sujeito e a violência na escola
Authors: Barchi Rodrigo , Rodrigues Frank Menezes
Published: September 2023

Este artigo aborda a vivência da violência na escola e como ela se encrava na constituição do sujeito. A perspectiva de análise recai sobre os efeitos dessa violência no sujeito que a pratica e que a presencia no ambiente escolar, trazendo à tona elementos sociais e psicanalíticos desse fenômeno. O objetivo é mostrar a violência na escola como parte constitutiva do sujeito, de sua compreensão de si e do mundo que o cerca. É realizado um debate conceitual ao redor da violência, da violência na escola e da violência na constituição das crianças e adolescentes, a partir de uma revisão bibliográfica ao redor do debate sobre violência na escola e subjetividade. Os resultados mostram que a violência na escola decorre das realidades de seus alunos, a partir de seus anseios e questões internas que sofrem influência do contexto social, cultural, econômico e apresentam as limitações destes jovens frente à realização de seus sonhos, sendo que isso leva à agressividade e destrutividade, que convergem para a noção de violência.
An Underwater Image Enhancement Model Combining Physical Priors and Residual Network
Authors: Fan Xinnan , Zhou Xuan , Chen Hongzhu , Xin Yuanxue , Shi Pengfei
Published: September 2023

Considering light absorbing and scattering problems in connection with
wavelength can decrease the visibility, contrast and color distortion of
images, we propose a new type of convolutional neural network with two
training phases. Firstly, the coordinate attention module is integrated
into the residual block of the residual group in the backbone network,
which is used to strengthen the feature extraction capability of the
network. Secondly, since the unrealistic image colors may degrade the
image details, an unsupervised method that combines the physical prior
knowledge and the real underwater images is proposed to finetune the
backbone network. Furthermore, a model protection mechanism is designed
to guarantee the successful execution of the training. The experimental
results indicate the proposed model can effectively optimize the
contrast, color and image quality of the underwater image. Compared with
relevant algorithms, our UCIQE and NIQE are respectively 0.525 and
4.149, which further verifies the superiority of the proposed model.
Medical error; Undoing the Wrong.
Authors: chiwhane anjalee , Chiwhane Yutheeka , paunikar vaishali
Published: September 2023

Background Though humans are fallible, Physicians as humans,
unfortunately, commit unintentional errors while providing healthcare
services. Medical errors are dangerous injuries caused to patients, by
physicians, nurses, or the medical team leading to harmful effects to
the patient that can be fatal. Clinicians can prevent medical errors in
healthcare with the use of diligence. In addition to the harm caused to
the patient, medical errors are expensive. Methods We searched the
PUBMED using the keywords ‘medical errors’, errors in medicine, and its
cost to human lives as well as its effect on healthcare providers and
reporting systems. Results Medication errors and Diagnosis errors
comprise a majority of medical errors. However, a lack of data, an
overlap in the definition of medical error, and the absence of
standardized nomenclature have led to difficulty in the evaluation and
analysis of data related to medical error. The remedial measures vary
from one setting to another, however efficient reporting and clinical
audits can help prevent medical errors. Conclusion Medical error is an
effect arising out of patient care that can be harmful and fatal to the
patients. This results in the failure of an action plan to be
implemented for treating a disease. Both patients and healthcare
providers are affected. Effective dialogue between the two,, clinical
audits ,a support system for healthcare providers and open disclosure
policy by the service provider are some effective measures to consider.
KEYWORDS: Medical error, Impact on healthcare provide, Solutions on
preventing error, Role of reporting and clinical audit
Molecular identification and antifungal susceptibility profiles of yeasts isolated from onychomycosis
Authors: yazdanpanah somayeh , Jabrodini Ahmad , motamedi marjan , Zomorodian Kamiar , Kharazi Mahboobeh , Shabanzadeh Shafigheh , Ghasemi Farnia , Shariat Sahar , Arab Maryam Rezaei
Published: September 2023

Candida onychomycosis is a common fungal infection affecting the nails,
primarily caused by Candida species. Regarding the increasing trend of
Candida onychomycosis and antifungal-resistant phenomenon in recent
years, this study aims to evaluate the epidemiological characteristics
of Candida onychomycosis, the distribution of emerging species, and the
antifungal susceptibility profiles of isolates. Onychomycosis caused by
yeast species was confirmed through direct examination and culture of
nail scraping among all individuals suspected to have onychomycosis and
referred to a medical mycology laboratory between June 2019 and March
2022. Species of yeast isolates were identified using the multiplex PCR
and RFLP-PCR methods. The antifungal susceptibility of isolates to
common antifungal agents and imidazole drugs was evaluated according to
the M-27 A3 CLSI protocol. Among 101 yeast strains isolated from
onychomycosis, Candida parapsilosis complex (50.49 %) was the most
common species, followed by C. albicans (20.79 %) and C. tropicalis
(10.89 %). Rare species of yeasts such as C. guilliermondii and
Saccharomyces cerevisiae were also identified by molecular methods.
Results obtained from antifungal susceptibility testing showed
significant differences in MIC values of isoconazole, fenticonazole, and
sertaconazole among different species. Overall, 3%
fluconazole-resistant rate was found among Candida species. Moreover,
there was a statistically significant difference in MICs of
fenticonazole and clotrimazole between the two most prevalent causative
species, C. parapsilosis complex and C. albicans. Correct identification
of the causative agents of onychomycosis and performing susceptibility
testing could be helpful in choosing the most appropriate antifungal
therapy.
Antibody mimetics: the next generation antibody engineering, a retrospective and prospective analysis
Authors: Dang Mei , Zhang Siran , Wu Longjiang
Published: September 2023

Antibody mimetics is a novel antibody engineering approach after the
development of polyclonal, monoclonal antibodies, and genetically
engineered antibody fragments. Inspired by the structure and function of
natural antibodies, antibody mimetics offer many advantages over
conventional antibodies and can be constructed by protein-directed
evolution, peptide design and synthesis, or fusion of
complementarity-determining regions through intervening framework
regions. A series of parent protein/peptide structures and technical
roadmaps have been established to induce better recognising properties,
superior affinity, stability, penetrability, and cost-effectiveness of
the designed mimetics. This article aims to summarise the evolution of
antibody mimetics engineering, illustrate the highlights and hotpots in
this research field using scientometric analysis, and give an
anticipatory analysis on this increasing research topic.
Popularność pieszej turystyki górskiej wśród studentów SGGW w Warszawie
Authors: Zawadka Jan , Wiśniewska Agata
Published: September 2023

Celem opracowania było rozpoznanie popularności pieszej turystyki górskiej wśród studentów SGGW w Warszawie oraz ukazanie ich motywów, preferencji i zachowań pod¬czas realizacji wyjazdów tego typu na terenie Polski. Badania, z udziałem 104 respondentów, zostały przeprowadzone w 2022 r. Metodą badań był sondaż diagnostyczny z wykorzystaniem techniki ankiety. Dominującym podczas wyjazdów w celu uprawiania pieszej turystyki górskiej okazał się motyw katartyczny (związany z chęcią odpoczynku i odreagowaniem stresu), a także motyw zdrowotny (poprawa samopoczucia fizyczno-psychicznego). Determinantami wyboru pasma górskiego lub szlaku turystycznego były walory przyrodnicze i krajobrazowe oraz po¬ziom trudności trasy. Najpopularniejszymi pasmami górskimi do realizacji wędrówek były Tatry i Bieszczady, a wyjazdy takie podejmowano najczęściej raz w roku. Miesiącem dominującym pod tym względem był wrzesień.
Technologie informacyjno-komunikacyjne jako determinanta rozwoju polskich przedsiębiorstw
Authors: Krzyżanowska Krystyna
Published: September 2023

Celem opracowania było przedstawienie stanu obecnego i możliwości rozwoju technologii informacyjno-komunikacyjnych w polskich przedsiębiorstwach na tle osiągnięć w krajach Unii Europejskiej. Aby zrealizować cel badań, wykorzystano literaturę przedmiotu, dane wtórne pochodzące z raportów o stanie sektora małych i średnich przedsiębiorstw w Polsce przygotowanych przez PARP w latach 2021 i 2022 oraz dane GUS. Z przeprowadzonej analizy wynika, że polskie przedsiębiorstwa w 2021 r. były bardzo dobrze wyposażone w sprzęt komputerowy, a także coraz częściej wykorzystywały nowoczesne technologie informatyczne. Systematycznie wzrastało zainteresowanie wszystkich grup przedsiębiorstw mediami społecznościowymi, chmurą obliczeniową i internetem rzeczy, przy czym przedsiębiorstwa duże i średnie wykorzystywały je częściej niż firmy małe.
DG_summ: A schema-driven approach for personalized summarizing heterogeneous data graphs
Authors: Beldi Amal , Sassi Salma , Chbeir Richard , Jemai Abderrazek
Published: September 2023

Advances in computing resources have enabled the processing of vast amounts of data. However, identifying trends in such data remains challenging for humans, especially in fields like medicine and social networks. These challenges make it difficult to process, analyze, and visualize the data. In this context, graph summarization has emerged as an effective framework aiming to facilitate the identification of structure and meaning in data. The problem of graph summarization has been studied in the literature and many approaches for static contexts are proposed to summarize the graph. These approaches provide a compressed version of the graph that removes many details while retaining its essential structure. However, they are computationally prohibitive and do not scale to large graphs in terms of both structure and content. Additionally, there is no framework providing summarization of mixed sources with the goal of creating a dynamic, syntactic, and semantic data summary. In this paper, our key contribution is focused on modeling data graphs, summarizing data from multiple sources using a schema-driven approach, and visualizing the graph summary version according to the needs of each user. We demonstrate this approach through a case study on the use of the E-health domain.
Banco sonoro participativo, construido a partir de la etno ornitología, asociado a las aves presentes en las comunidades indígenas aledañas al casco urbano de Mitú, Vaupés.
Authors: Guerrero-Peláez Sebastian , Rivera Velasco Gloria Amparo , Murillo López Laura Alejandra , López Peña Yenifer Soledad , González Vásquez Yorneida Anayiber , Palacios Rojas Manuel Vicente , Castillo Sanchez Marcelo Bibiano
Published: September 2023

El consumo y producción de material audiovisual se ha triplicado en los últimos años en países comoColombia. Es por ello, que a nivel nacional se ha venido trabajando la acústica como medio deproducción de material auditivo para diferentes usos, tales como el proyecto “Banco de contenidos,huellas de memoria viva” de la RTVC para recuperar, restaurar y almacenar los registros sonoros delas producción audiovisuales de diferentes épocas de Colombia, el proyecto “como suena Colombia”en donde recolectan registros de sonidos locales y los bancos de sonidos de animales (BSa) delInstituto Alexander Von Humboldt como aporte a la construcción científica del pais y conservaciónde la biodiversidad.
PENGEMBANGAN PRODUK OLAHAN BERBASIS PERIKANAN SEBAGAI PENUNJANG PARIWISATA DI DESA SAMBIGEDE KECAMATAN SUMBERPUCUNG KABUPATEN MALANG
Authors: Kiranawati Titi Mutiara
Published: September 2023

Desa Sambigede Kecamatan Sumberpucung Kabupaten Malang, merupakan desa yang mempunyai potensi sumber daya alam perikanan yang melimpah serta potensi wisata Kebon Watu. Ekonomi masyarakat bertumpu pada hasil perikanan, seperti menjual ikan segar di pasar setempat. Masyarakat belum mampu mengembangkan secara maksimal keunggulan tersebut untuk dijadikan sebagai sumber penghasilan. Permasalahan yang dirasakan yaitu tingkat pengetahuan masyarakat dalam teknologi pengolahan produk olahan hasil perikanan yang bermutu atau sesuai Standar Nasional Indonesia masih rendah. Kegiatan pengabdian pada masyarakat ini bertujuan mentransfer ilmu pengetahuan dan keterampilan pengolahan ikan untuk meningkatkan pendapatan masyarakat dan sebagai penunjang pariwisata. Metode pelaksanaan yaitu dengan melakukan pelatihan dan pendampingan. Hasil kegiatan pendampingan ini adalah masyarakat dapat memanfaatkan ikan menjadi kerupuk tulang dan kulit ikan, Basreng, dendeng ikan dan opak singkong rasa ikan. Penyuluhan dan pendampingan meningkatkan pengetahuan dan keterampilan masyarakat dalam pengolahan ikan
PENGEMBANGAN PAKET WISATA EDUKASI TENUN ENDEK DARI HULU HINGGA HILIR DI DESA SINABUN
Authors: Karyasa I Wayan , Wijaya Made Agus , Astawa I Gede Putu Banu
Published: September 2023

Pengembangan paket wisata edukasi tenun endek merupakan salah satu kegiatan dalam Program Desa Binaan Merintis Desa Wisata Tenun Endek di Desa Sinabun. Tujuan dari tulisan ini adalah membahas potensi dan kendala yang dihadapi masyarakat Desa Sinabun dalam mengembangkan paket wisata tenun endek dari hulu hingga hilir. Pendekatan partisipatif dengan konsep belajar di masyarakat diterapkan dalam menggali potensi, persoalan dan solusi dalam mengembangkan paket wisata tenun endek dengan melibatkan tokoh-tokoh kunci Desa Sinabun. Sedangkan metode yang diterapkan dalam program ini adalah metode pemberdayaan masyarakat partisipatif dengan mengadopsi model 7D dari Dharmotharan. Hasil kegiatan berupa peta potensi, peta kendala, dan alternatif-alternatif solusi yang dijadikan landasan dalam menyusun rencana induk pengembangan desa wisata tenun endek dari hulu hingga hilir. Pembelajaran bersama yang diperoleh adalah komitmen dukungan untuk membangun secara berkelanjutan desa wisata melalui rintisan paket wisata tenun endek sebagai daya ungkitnya.
IMPLEMENTASI SPORT SCIENCE DALAM PENANGANAN CEDERA DI PERGURUAN SILAT SATRIA MUDA INDONESIA UNIT PANJI ANOM
Authors: Kusuma Ketut Chandra Adinata , Luh Putu Tuti Ariani  , I Wayan Muliarta
Published: September 2023

Cedera olahraga merupakan salah satu faktor penghambat atlet untuk meningkatkan performa maupun mencapai prestasi tertinggi. Pencak silat merupakan olahraga bela diri dengan karakteristik full body contact, berpotensi menimbulkan cedera bagi atletnya. Tujuan kegiatan ini adalah untuk memberikan pemahaman tentang penanganan cedera olahraga kepada atlet Perguruan Silat Satria Muda Indonesia (PS SMI) Unit Panji Anom yang berbasis sport science. Metode yang digunakan dalam kegiatan ini diawali proses pemberian materi secara teoritis, dilanjutkan memberikan pendampingan penanganan cedera, dan diakhiri dengan proses evaluasi menggunakan instrumen unjuk kerja untuk mengukur tingkat keterampilan para peserta dalam menangani kasus cedera. Peserta yang terlibat sejumlah 20 pesilat PS SMI Panji Anom. Narasumber yang dihadirkan yaitu salah satu dosen Fakultas Kedokteran Undiksha.  Melalui pelatihan dan pendampingan yang dilakukan oleh narasumber, maka pemahaman dan keterampilan para peserta telah berhasil mencapai nilai dengan rata-rata 89 atau secara individu semua peserta telah meraih nilai di atas 70. Disimpulkan bahwa seluruh peserta telah memiliki pemahaman dalam penanganan cedera menggunakan metode RICE. Diharapkan pasca kegiatan ini, peserta secara konsisten untuk mengimplementasikan penanganan cedera menggunakan metode RICE apabila ditemukan kasus cedera baik saat latihan maupun bertanding.
MENYIAPKAN GENERASI SEHAT BERPRESTASI BEBAS STUNTING MELALUI PENDAMPINGAN IBU “ASIEK” DI DESA TEGAL LINGGAH WILAYAH KERJA PUSKESMAS SUKASADA I
Authors: Luh Mertasari , Wayan Sugandini  , Komang Sulyastini
Published: September 2023

Pemberian ASI Eksklusif merupakan strategi awal dalam pencegahan stunting di Indonesia. Namun saat ini cakupannya masih rendah karena pemberian MP ASI yang tidak logis. Tujuan pengabdian untuk mensukseskan program ASI eksklusif. Pendampingan, dan pemberian edukasi secara individu dan kelompok.  Adapun hasil pendampingan dari tanggal 10 Mei - 25 Juli 2022 adalah dari 20 ibu menyusui terdapat 10 orang yang berhasil ASI eksklusif, 2 orang mengalami bendungan ASI dan tetap menyusui, 1 orang gagal MAL tapi tetap menyusui,5 orang sedang proses ASI ekslusif, dan 5 orang yang drop out ASI karena ASI tidak cukup pada bulan ke 4. Hasil penimbangan bulan Juli total bayi mengalami kenaikan berat badan dan dengan hasil deteksi perkembangan normal. Melakukan pendampingan Ibu ASIEk cukup efektif untuk mensukseskan program ASI ekslusif, mencegah dan mengatasi permasalahan menyusui dan menciptakan generasi sehat bebas stunting.

 

Kata Kunci : Pendapingan, ASI Ekslusif, stunting.
PENYULUHAN PERAWATAN KAKI DIABETIK KEPADA PESERTA PROGRAM PROLANIS DI PUSKESMAS BULELENG II TAHUN 2022
Authors: I Gede Surya Dinata  , Udrayana Oka , Ketut Suparna  , Ida Ayu Setyawati Sri Krisna Dewi  , Kadek Surya Candra Wijaya
Published: September 2023

Jumlah pengidap penyakit diabetes mellitus (DM) terus meningkat setiap tahun, seiring perubahan gaya hidup masyarakat global yang tidak sehat. Diperkirakan di seluruh dunia, lebih dari 500 juta orang dewasa hidup dengan DM. Peningkatan ini berdampak pada tingginya angka komplikasi DM, khususnya pada kaki akibat kerusakan pembuluh darah, saraf, gangguan system imun dan penyembuhan luka. Komplikasi DM pada kaki berupa adanya luka, infeksi, perubahan bentuk kaki yang sangat mengurangi kualitas hidup dan menjadi beban sosial dan kesehatan yang berat. Untuk itu diperlukan upaya pencegahan terjadinya komplikasi pada kaki pengidap DM untuk mencegah perburukan penyakit dan penurunan kualitas hidupnya. Salah satu upaya yang dapat dilakukan adalah dengan mengadakan edukasi kepada pengidap penyakit DM, yang sebagian besar berobat ke Puskesmas sebagai peserta Prolanis, dengan metode penyuluhan dan diskusi dua arah. Edukasi dengan metode ceramah, dilaksanakan pada peserta Prolanis di Puskesmas Buleleng II, diharapkan dapat meningkatkan pengetahuan, kesadaran dan mampu melakukan tindakan perawatan kaki diabetic. Tanpa pemberian informasi yang baik, sehingga tidak memiliki pengetahuan yang benar, pengidap DM berisiko mengalami komplikasi pada kaki yang cukup serius, memerlukan perawatan di rumah sakit, bahkan kehilangan tungkai dan berakibat fatal.
PEMETAAN KEDALAMAN LAUT UNTUK ZONA BUDIDAYA TERUMBU KARANG
Authors: I Putu Ananda Citra  , I Wayan Krisna Eka Putra  , I Made Sarmita
Published: September 2023

Desa Temukus Kecamatan Banjar merupakan desa pesisir yang mengembangkan wilayah pesisir dengan salah satu programnya adalah budidaya terumbu karang. Namun, menemui kesulitan untuk memetakan kedalaman laut sebagai salah satu syarat budidaya terumbu karang. Tujuan dari kegiatan ini membuat Peta Batimetri wilayah pesisir Desa Temukus secara partisipatif. Masyarakat yang dilibatkan adalah kelompok nelayan, kelompok masyarakat pengawas dan kelompok sadar wisata Desa Temukus. Pendekatan partisipatif kepada kelompok masyarakat sasaran. Metode pemberdayaan masyarakat yaitu dengan metode diskusi, praktek kerja lapangan, dan pelatihan serta pendampingan. Hasil kegiatan menunjukkan antusias dan keaktifan dari kelompok sasaran. Menggunakan GPS dan Aquamaps dalam proses pemetaan kedalaman laut. Peta kedalaman laut (Peta Batrimetri) Desa Temukus sebagai dasar pembuatan zona konservasi wilayah pesisir. Konservasi wilayah pesisir dengan menentukan zona untuk pengembangan ekosistem terumbu karang. Pemetaan kedalam laut sebagai salah satu syarat hidup dari terumbu karang. Melibatkan kelompok nelayan, masyarakat pengawas, dan kelompok sadar wisata dalam tahap pembibitan, penanaman, pemeliharaan, pengawasan zona terumbu karang secara sistematis. Keberlanjutan kegiatan sangat memungkinkan karena pemahaman pentingnya menjaga terumbu karang sudah disadari dalam menjaga ekosistem laut terutama perikanan dan pariwisata.
PEMANFAATAN DAN PENGOLAHAN PULP KOPI ROBUSTA MENJADI VINEGAR
Authors: Mangku I Gede Pasek , Luh Suriati  , Girindra Anak Agung Ngurah Surya , Tresna Wati Gek Ayu Sagita Widya
Published: September 2023

Berbagai produk inovatif dapat dihasilkan dari limbah pengolahan kopi. Mengolah limbah kopi, meningkatkan nilai ekonomi, dan meminimalkan kerusakan lingkungan. Vinegar merupakan salah satu inovasi produk yang dapat dihasilkan dari limbah (pulp) kopi. “Bumdes Eka Giri Karya Utama” sebagai mitra dan kelompok tani kopi belum memiliki pengetahuan dan keterampilan mengolah pulp kopi menjadi vinegar. Kegiatan pengabdian masyarakat ini bertujuan untuk berbagi informasi teknologi pengolahan vinegar dari pulp kopi kepada para peserta serta menambah pengetahuan dan keterampilan para peserta yang berasal dari “Bumdes Eka Giri Karya Utama, kelompok tani kopi, petugas PPL, staf desa, dan mahasiswa. Metode yang digunakan dalam kegiatan pengabdian masyarakat ini adalah survei, transfer pengetahuan dan keterampilan, praktik dan demonstrasi, dokumentasi, serta diskusi. Hasil pengabdian menunjukkan bahwa teknologi pengolahan vinegar dapat diterima dengan baik oleh peserta dan mereka juga dapat mengolah pulp kopi menjadi vinegar dan produk ini dapat digunakan untuk makanan alternatif. Cara ini dapat digunakan sebagai alternatif untuk meminimalisir pencemaran lingkungan akibat limbah kopi. Namun vinegar ini masih membutuhkan kajian lebih lanjut terutama untuk meningkatkan kualitasnya
PENERAPAN KALKULATOR DETEKSI (KOKI) SEBAGAI APLIKASI BERBASIS WEB UNTUK DETEKSI DINI STUNTING BAGI KADER POSYANDU DI WILAYAH KERJA PUSKESMAS SUKASADA I
Authors: Pratiwi Putu Irma , Gozali Wigutomo , Giri Ketut Espana , Astuti Anjar Tri , Sekarini Nyoman Ayu Desy
Published: September 2023

Stunting pada masa balita dapat meningkatkan terjadinya morbilitas, anak-anak mengalami kesulitan dalam hal belajar, stunting pada masa balita memungkinkan untuk memiliki status pendek dimasa dewasa. Masyarakat seringkali mengalami kesulitan dalam melakukan deteksi terhadap stunting, karena perawakan yang pendek dianggap sangat umum sehingga merukan hal normal bagi masyarakat. Pengukuran pertumbuhan yang efektif dapat membantu meningkatkan kualitas hidup balita. Pos Pelayanan Terpadu (Posyandu) merupakan salah satu tempat pelayanan kesehatan yang bersumberdaya masyarakat yang melakukan pemantauan terhadap pertumbuhan anak. Tujuan dari pengabdian ini adalah untuk meningkatkan pengetahuan dan keterampilan kader posyandu dalam melakukan deteksi dini terhadap stunting melalui aplikasi berbasis web. Metode pengabdian adalah dengan pelatihan dan pendampingan terhadap 15 orang kader posyandu. Hasil dari pengabdian ini adalah terdapat peningkatan pengetahuan kader posyandu setelah diberikan pelatihan serta seluruh kader posyandu mau dan mampu menerapkan penggunaan aplikasi berbasis web untuk mendeteksi dini stunting pada saat pelaksanaan posyandu.