bluuebunny/crossref_metadata_2025 huggingface dataset:
Formation of a New German Identity in the Context of Mediatization of the Political Environment
Authors: Arzamanova Tatiana
Published: May 2024

The modern stage of the development of the information society carries with it certain associated risks, such as problems of digital security, digital inequality, significant updating and increasing influence of the information environment. In the context of the global information space, de facto turning into a global player, the excessive growth of the influence of the information environment leads to the mediatization of processes (including decision-making processes), and as a result, is able to have a significant impact on the political environment in a short time. The article attempts to analyze the current phenomenon of international relations as an example of such an impact, namely, Germany’s search for a new identity in the context of fundamental movements in the Euro-Atlantic coordinate system that have occurred over the past year. At the same time, special attention is paid to the fact that the revision of the central dogmas of German foreign and security policy, the process of forming a new identity take place in conditions when the data of representative studies clearly demonstrate the obvious unwillingness of German society to such large-scale changes, primarily at the mental level. The multi-vector analysis allows us to come to the following conclusion: the legitimization of the “remilitarization” of Germany occurs in conditions when a broad consensus has not yet been formed at the level of the decision-making system and civil society as a whole on the acceptability of such dynamics of advancing a new agenda. Thus, illustrating the determining external influence on political communications, including from the media environment as a “converter” (and not a repeater) of the internal impulses of the political system through manipulating the images created and forming new socially important meanings in the media space.
“The Anger of a Deity Dwelling in a Mountain”: the Specific Aspects of the Perception of Volcanic Eruptions in the Heian Japan
Authors: Grachyov Maxim
Published: May 2024

Volcanic eruptions, hurricanes and earthquakes are the most powerful forces on Earth. Scientists are trying to understand these dangerous phenomena, however, despite the increasing dominance of man over nature, they still confuse, frighten and depress human minds. Every year, volcanic activity (about 60 eruptions a year), typhoons and earthquakes cause destruction in many parts of the world and bring death to living beings. Most volcanoes are located in the zone of the Pacific Ring of Fire: a region around the rim of the Pacific Ocean, where lithospheric plates collide and form breaks, from which molten magma flows upward. Thick magma filled with gases provokes explosive eruptions. In ancient times, in different parts of the world, and Japan is no exception, natural disasters caused superstitious fear, and also were the object of admiration and religious worship. Despite the fact that natural anomalies in ancient and medieval Japan caused anxiety, they were also often seen as a foretoken of future misfortunes that could bring discord into the normal way of life. In those distant times, the natural and social orders were perceived as interrelated phenomena, and not a single unusual phenomenon of nature could remain undiscovered. In case of any manifestations of natural disorder, it was necessary to prevent or weaken any likely adverse consequences with the help of various prohibitive regulations as well as magic and ritual actions. This article is devoted to the specific perception of volcanic eruptions in the Heian era (mainly in the 9th century). In the conditions of numerous eruptions in at the territory of the Japanese archipelago and the inability to focus on Chinese political texts due to not so high volcanic activity in China, the Japanese political elite had to create their own algorithm for interpreting the causes of volcanic eruptions, which was based on native Japanese beliefs, where mountains were revered as sacred objects and often perceived as the abode of deities. The study is based on historical sources of various types: chronicles (“Nihon koki”, “Shoku Nihon koki”, “Nihon sandai jitsuroku”, “Nihon kiryaku”) and collections of act material (“Ruiju sandaikyaku”), as well as research literature, mainly in Japanese.
Materials on the Historical and Statistical Description of the Orenburg Cossack Army as a Collection of Historical Sources for the Study of Acculturation Processes on the Southeastern Frontier of the Russian Empire
Authors: Godovova Elena
Published: May 2024

The article analyzes the historical sources collected in the Materials on the historical and statistical description of the Orenburg Cossack army. The four groups of source material identified by the author are extracts from the files of the military archive; legislative and regulatory legal acts; stories, travel notes and memoirs of Cossack officers; oral historical evidence — contains unique evidence of the imperial policy of acculturation in relation to the Orenburg Cossack army, occupying the frontier territory of the south-east of the Russian Empire and created by the government to protect this state border. The author comes to the conclusion that the historical sources presented in the Materials on the historical and statistical description of the Orenburg Cossack army reflect the confessional and ethnic processes in the army, the education of the Cossack spirit in military field conditions and in conditions of extreme captivity, allow us to understand the problem of formation among the Orenburg Cossacks and preservation of the Cossack identity.
The Policy of the Provincial Authorities of the Southern Urals in Relations with the Kazakh Population in Late Imperial Russia (1911—1916)
Authors: Valevko Stanislav
Published: May 2024

This article is devoted to the policy of the provincial authorities of late imperial Russia in the southern Urals in relation to the Kazakh population, its acculturation, using the example of four main aspects of interaction, namely education, health, cattle breeding, as well as agriculture, which appeared among the nomads under the influence of the Russian population. The policy of incorporation or acculturation of the nomadic Kazakh population was necessary to ensure stability in the multi-confessional and multicultural regions of the country, such as the southern Urals and the Volga region. This policy especially affected the formation of the education system in the 19th century, but only from the second half of it became systemic. This allowed the formation of the Kazakh intelligentsia. As for health care in the region, it can be said that the local authorities saw their main task as fighting epidemics, which they successfully coped with. In the field of agriculture and cattle breeding, attempts by the authorities to influence the nomadic population have been manifested since the second half of the 19th century, but only in 1911—1912 the policy in these industries became systematic and effective.
Repatriation Policy of the Republic of Kazakhstan: from “Oralman” to “Kandas”
Authors: Kovalskaya Svetlana
Published: May 2024

The article analyzes the repatriation policy of the Kazakhstan from the era of the late USSR 1991 until our days and presents field materials of the research conducted in different cities from 2019 to 2021 (Ust-Kamenogorsk, Astana, the villages of Akmola region - Karaotkel and Koyandy). We have used materials of the field expeditions conducted in 2014 and 2019 in Western Mongolia (Bayan-Ulgiy) among ethnic Kazakhs. During the field expeditions, the goal was to identify the reasons for repatriation and find out the process of integration of immigrants into Kazakhstani society. It was supposed to answer the question of whether the repatriation policy could be considered successful. The authors relied on a transnational approach to study the process of the return of ethnic Kazakhs to their historical homelandas well as the theory of acculturation, through the prism of which the problems of repatriation are shown.The authors were guided by the method of biographical interviewing and participant observation. The article uses archival materials extracted from the National Archives of the Republic of Kazakhstan (Astana) and the Archive of the President of the Republic of Kazakhstan (Almaty). The reason for migration for repatriates is not only their desire to reunite with their homeland. One of the attractive factors is the desire for self-preservation of ethnicity and ensuring a successful life for the repatriates themselves and their children. The integration of repatriates takes place in different ways depending on the country of origin and on the generation of those who arrived. There are certain boundaries and rejection both between the migrants themselves, the repatriates and the locals, which are manifested not only in their behavior towards each other but also in a broader sociocultural understanding.
Evaluation of the Neuroprotective Action of Azadirachta indica Leaves Extract in Streptozotocin-induced Diabetic Rodent Model
Authors: Ghosh Arijit , Ghosh Sougata , Ray Moumita , Indu Rania , Bhattacharya Sangita , Adhikari Anjan , Bose Sankhadip , Banerjee Sabyasachi , Sur Pradip Kumar
Published: May 2024

Among the most common and painful consequences of diabetes mellitus, Diabetic Peripheral Neuropathy (DPN) is one of the most common. For DPN management, a variety of techniques have been used, ranging from traditional medicines to alternative approaches. Natural compounds are also the focus of research to explore the possible treatment by replacing or combining with the existing therapies. Different neurological changes in diabetic neuropathy and the effect of the Azadirachta indica (neem) extract were assessed with nerve conduction velocity, and biochemical and histological analysis in Streptozotocin-induced diabetic mellitus. The therapeutic effect of the extract was evaluated with doses 100, 200 and 500mg/kg body weight for 4 weeks after induction of diabetes. The protective effect was evaluated by treating the animals with hydroalcoholic extract of neem leaves in 500mg/kg dose before the induction of diabetes and post-treatment with the standard drug Metformin (500mg/kg). Both resulted in a significant reduction in blood glucose, additionally, 500mg/kg body weight dose revealed the signs of neuroprotection in diabetic rats. Neem leaf extract appears to be promising for future investigations, which might contribute to the emergence of new drugs for diabetes treatment and diabetic neuropathy either alone or in combination with conventional therapies.
Development and Evaluation of Polyherbal Hair Dye Formulation
Authors: Subramanian Poonguzhali , Kalusalingam Anandarajagopal , Kaliyappan Deviga , Binti Zaki Fatin Natasha , Mohan Pavitra , Damoothran Pavitra , Fei Ng Jeck , Khan Abdullah
Published: May 2024

Background and objectives: Hair care products including hair dye play an important role in the maintenance and enhancement of appearance and overall wellbeing of the hair. Most of the hair dye available in the market contains harmful chemicals that may cause allergic reactions or irritation of the scalp. The objective of this study focuses on the formulation and evaluation of hair dye as creams and gels with different shades by using herbs. Methodology: The collected plants were authenticated, and shade dried. Then, extractions were done using water, ethanol, and methanol. Preliminary testing was conducted to obtain burgundy, brown and black by manipulating the ratios. Later, almond oil, coconut oil, beeswax and Carbopol-934 gel were added to ease the penetration. Finally, accelerated stability studies were done to check the physical and microbial stability of the product. Results: Eight different shades of hair dye were formulated in gel and cream form. Among them gel formulation F5 and F6 as well as the cream formulations F1, F2, F3, F4, F7 and F8 demonstrated good staining and better colour intensity. The accelerated stability studies of F1 to F8 revealed that there is no change in the physical evaluation and no evidence of microbial contamination. Conclusion: The output of this research is suitable for all races and age group because it is not a permanent hair dye that might have a restriction for some groups of races. As such, this hair dye is fully formulated with natural sources by considering in the reduction of severe side effects to the consumers.
Bioactivity of Lantana camara Flowers: Antilithiatic and Nephroprotective Implications in Male Wistar Rats
Authors: Arra Keerthana , Pasupula Rajeshwari , Singireddy Anandam
Published: May 2024

Lantana camara is a well-known medicinal plant with various reported therapeutic compounds. This study explores the antilithiatic and nephroprotective effects of Lantana camara flower hydroalcoholic extract. Using animal models and cell culture, we assessed its impact on ethylene glycol-induced nephrolithiasis and gentamicin-induced nephrotoxicity. The ethylene glycol-induced nephrolithiasis model revealed elevated levels of calcium, phosphate, and oxalate, indicating the formation of calculi. Treatment with the hydroalcoholic extract resulted in a significant decrease in uric acid levels, reducing the likelihood of calculi formation. Additionally, the animals treated with the extract showed reduced levels of urea, and creatinine, indicating improved kidney function. The results highlighted the notable difference between the preventive and curative treatments. In the HEK-293 cell culture, the hydroalcoholic extract demonstrated a significant inhibition of abnormal cell morphology induced by gentamicin, a nephrotoxic drug. The extract also exhibited a marked improvement in cell growth compared to the standard treatment. The findings of this study provide substantial evidence supporting the antilithiatic and nephroprotective effects of the hydroalcoholic extract of Lantana camara flowers. The extract effectively reduced the risk of calculi formation, improved renal parameters, and demonstrated potential in mitigating drug-induced nephrotoxicity. These results validate the traditional claims regarding the efficacy of Lantana camara as a therapeutic agent for kidney-related disorders. The hydroalcoholic extract of Lantana camara flowers could serve as a valuable alternative treatment option, offering potential benefits in the management of lithiasis and nephrotoxicity.
A Review Article on the Role of Ingredients of Kshara Vasti (Medicated Enema) on Gut Microbiota of Rheumatoid Arthritis Patients
Authors: Aswathy Y. S. , Prathibha C. K. , Raman Sujatha , Dharmarajan Prasanth , Anandaraman P. V.
Published: May 2024

Kshara Vasti (medicated enema) is an important treatment in the management of Amavata which is correlated with Rheumatoid Arthritis (RA). The ingredients of Kshara Vasti have the property to act against Ama which is a root cause of the development of the disease. The main aim of this review is to study the role of ingredients of Kshara Vasti on the gut microbiota of RA patients. Jaggery, tamarind and rock salt have been proven to have a positive effect on the gut microbiome by enhancing the abundance of health-promoting species. Cow’s Urine (CU)/Cow Urine Distillate (CUD) enhances the bioavailability and efficacy of a drug with which it is co-administered. Anethum sowa has a significant impact on caecal microbiota. The production of Short-Chain Fatty Acids (SCFAs ) by Gut Microbiota (GM) may be a probable mode of action for the suppression of inflammatory conditions like RA. Each constituent in Kshara Vasti has a positive impact on modulating gut microbiota.
Exploring Stevia: A Natural Sweetener with Multifaceted Health Benefits
Authors: Sadhu Piyushkumar , Rathod Falguni , Kumari Mamta , Shah Niyati , Talele Chitrali , Aundhia Chintan
Published: May 2024

Natural sweeteners, especially those derived from plants, have become popular as low-calorie options compared to traditional sweeteners. Such discussion explores the world of natural sweeteners, emphasizing the growing demand for alternatives to artificial ones like saccharin and cyclamates. These sweeteners, sourced from plants, fruits, and honey, provide a healthier choice with fewer calories. Stevia, extracted from the Stevia rebaudiana plant, is a notable natural sweetener due to its zero-calorie content and strong sweetness. The review explores the background of Stevia, its glycoside compounds, and how it attains its sweetness. The pharmacological aspects of Stevia are also explored, highlighting its potential benefits in managing Type 2 diabetes, reducing blood pressure, alleviating inflammation, acting as an antioxidant, and showing anticancer properties. Studies suggested that Stevia’s active ingredients, are primarily Stevioside and Rebaudioside A, contribute to its sweetness. The chemical composition of these active ingredients is influenced by factors like geographical location, cultivars, and processing methods. Stevia offers advantages such as low caloric content, suitability for diabetics, and benefits for dental health, making it an appealing sugar substitute for those focused on weight management and a health-conscious lifestyle. However, it is important to note potential drawbacks, including a bitter aftertaste, individual sensitivities, and regulatory considerations. Some commercial Stevia products may contain additives that impact their nutritional profile. Despite these factors, high-purity Stevia extracts have received safety approvals from global food safety authorities. In summary, Stevia emerges as a natural sweetener with the potential to address health-related concerns linked to traditional sugar consumption.
In Silico Screening of a Phytochemical Naringin, Isolated from Citrus decumana var. paradisi Against the Genes of Polycystic Ovary Syndromenes of Polycystic Ovary Syndrome
Authors: Rana Babita , Merwyn Dcosta  , Arvind Singh
Published: May 2024

Polycystic Ovary Syndrome (PCOS) is a complex hormonal and metabolic disorder. The overproduction of androgens is the primary feature of PCOS. The currently available pharmacological agents recommended for the treatment of PCOS are linked with several adverse effects. Therefore, herbal-based drugs with lesser side effects, have become a favourable trend among people. A flavonoid glycoside, naringin isolated from different fruit parts of Citrus decumana var. paradisi (Macfad.) H.H.A. Nicholls exhibits a wide range of therapeutic properties. In the traditional system of medicine, it is used to improve ovarian health. To set down scientific evidence, molecular docking analysis was performed to find out the binding affinity of compound naringin with the protein CYP 17-cytochrome P 450, attributing to hyperandrogenism due to its overexpression, leading to PCOS. The docking score values were compared with the standard drug metformin to interpret the effectiveness of flavonoid naringin in the treatment of PCOS.
Mixoma auricular izquierdo: reporte de caso
Authors: Conta Lopez John Alexander , Gutiérrez-Villamil Daniel Felipe , Vargas Rodríguez Ledmar Jovanny
Published: May 2024

La presentación de los tumores cardíacos es poco frecuente, y son los mixomas cardiacos (cm) los más comunes; se calcula que son el 70 % de todos los tumores benignos primarios cardiacos y, de estos, más del 75 % de los mixomas se origina en la aurícula izquierda. Mujer de 40 años de edad, con síncope referido por testigo, con posterior bradipsiquia e hipoactividad, pérdida de peso de 13 kg. Al ingreso refirió paresias en manos y pies del hemicuerpo izquierdo, disartria leve, disminución de la mímica facial izquierda. Resonancia de cerebro mostraba múltiples focos de comportamiento isquémico, considerando enfermedad tromboembólica. El ecocardiograma denotaba masa con imágenes móviles sugestivas de tumor tipo mixoma en primera opción, con alta probabilidad de embolia tumoral. Ante estos hallazgos, se decidió solicitar remisión a cirugía cardiovascular, por masa intracardiaca con muy alto riesgo embólico, donde se confirmó mediante estudio histopatológico que la masa correspondía a un mixoma auricular. La presencia de masas intracardiacas es rara, con una baja prevalencia general. La prevalencia de mixomas es de un 58,14 % [ic 95 % = 51,95; 64,09 %], concluyendo al mixoma como más común. La tríada clínica que puede generar se compone de cuadros sincopales, tromboembolismos y síntomas constitucionales. La imagenología son los estudios de primera línea en la identificación.
Ukraine’s efforts against money laundering since the Russian invasion in February 2022
Authors: Blümel Alexander
Published: May 2024

The shifting environment of money laundering, exacerbated due to the war, calls for scrutiny of Ukraine's reaction to this fundamental challenge. This paper thus helps widen the knowledge about how Ukraine is trying to fight against money laundering and protect financial system integrity by shedding light on legislative transformations and their results in a much more complex geopolitical setting. Therefore, it provides an overview about the main elements of Ukrainian anti- money laundering policy and an analysis of reforms passed in this sphere of law since the full-scale invasion of Russia into Ukraine 2022. It focuses on the main changes of legislature in terms of anti-money laundering and terrorism financing prevention as well as first identifiable results of the new legislatorial and executive changes.
Juridical review regarding maladministration of crude palm oil exports in Indonesia
Authors: Santiago Faisal
Published: May 2024

This paper tracks the maladministration of CPO exports by conducting a judicial review of CPO export policies by the Ministry of Trade of the Republic of Indonesia. This study uses a normative legal analysis with a field research approach. The results of the judicial review of this study are that the policy of temporarily stopping the export of Crude Palm Oil by the government is entirely appropriate, considering that previously there was maladministration carried out by individuals at the Ministry of Trade involving palm oil entrepreneurs in three companies, the occurrence of export permits has entered the criteria for maladministration because the three companies The CPO manager does not have an export permit which causes state economic losses due to rising cooking oil prices due to excess CPO being exported.
Force majeure during the war. Review of juridical practice
Authors: Abramovych Ruslana
Published: May 2024

This review covers the judicial practice of Ukrainian courts of general jurisdiction related to the issue of force majeure. The question becomes especially relevant in the current war realities, in which not only the citizens of the country, but also business entities find themselves. Under the conditions of martial law, counterparties often resort to abuses, citing force majeure, and refuse to fully or partially fulfill their contractual obligations. This publication examines the main legal positions of courts of general jurisdiction on this topic.
Evaluation of the Factors Associated with Post-Operative Outcome in Patients of Ulcerative Colitis Undergoing Ileal Pouchanal Anastomosis with Comparison of Functional Outcome between Stapler and Hand-Sewn Anastomosis
Authors:   Department of Surgical Gastroenterology SVP Hospital, Ahmedabad, Gujarat, Soni Dr Aakanksha
Published: May 2024

ntroduction Ulcerative colitis defined as a non-granulomatous idiopathic inflammatory disease which mainly affects the colon and rectum. The disease may arise at any age but most commonly affects the adults between the age group of 30–40 years.1,2. The etiology of the disease is multifactorial, involving genetic predisposition, dysregulated immune responses, epithelial barrier defects and environmental factors. No sex predilection is seen in ulcerative colitis.3,5 The peak age of onset of disease is between 30 to 40 years.4,6 The environmental factors has also been found to play an important role in the etiopathogenesis of ulcerative colitis. Cigarette smoking is one of the major factor associated with ulcerative colitis, non-smokers have a milder disease course and active smokers are less likely to develop ulcerative colitis7 Appendectomy also confers a protective effect against ulcerative colitis, especially in young patients operated for acute appendicitis.8. Classic findings in endoscopy in patients with ulcerative colitis include loss of normal vascular pattern, erythema, erosions, granularity, friability, ulcerations and bleeding9 . The primary aim of medical management is to induce and maintain remission with the long-term goals of improving quality of life and prevent disability. Absolute indications for surgery include uncontrolled hemorrhage, perforation, and colorectal carcinoma or dysplastic lesions not amenable to endoscopic removal.10 Surgery is also indicated in refractory acute severe ulcerative colitis or medically refractory disease. The most commonly performed surgery for ulcerative colitis is restorative proctocolectomy with ileal pouchanal anastomosis (IPAA). An important aspect of the surgery is the use of either sutures or staplers for anastomosis. Two types of ileal pouch-anal anastomosis (IPAA) have been described: a mucosectomy of the rectal stump followed by a hand-sewn ileal pouch-anal anastomosis.11 The alternative technique is to retain the mucosa of the rectal stump and perform a stapled pouch-anal anastomosis.
Mediastinal Tuberculosis with Sternal Encroachment - A Rare Presentation of Tuberculosis
Authors:   1Professor and HOD in Pulmonology- Dr VRK Women’s Medical College, Teaching Hospital and Research Centre, Consultant Pulmonologist, Omega Hospital, Gachibowli, Hussain Dr Hidayath
Published: May 2024

Introduction Extra-pulmonary tuberculosis constitutes 15-20% of the total tuberculosis (TB) caseload in immunocompetent patients. Affliction of the skeletal system is rare with still rarer presentation of sternal tuberculosis. Sternum is one of the least common bones of the body to get infected (1) Sternal TB is predominantly seen in middle-aged adults although no age is immune and it has also been reported in an infant. It can arise primarily due to a hematogenous route or direct extension from the hilar lymph nodes and/or could be due to lymphatic disseminatio(2) . Sternal tuberculosis has also been reported after BCG vaccination in the pediatric age group (3-5) Here we present an unusual case of tuberculosis of the sternum, which presented with swelling and pain in the chest in a 9 year old boy. Keywords: Sternal tuberculosis, Manubrium sterni, Skeletal Tuberculosis, Pediatric sternal tuberculosis, Mediastinal Koch’s
Comparative Study between Operative and Non-Operative Management of Complete Achilles Tendon Rupture
Authors:   Resident, Department of Orthopedics (KMCH), Mazhar Dr Md.
Published: May 2024

ntroduction Achilles tendon rupture is the most common tendon rupture in the lower extremity. The injury most commonly occurs in adults in their third to fifth decade of life.[1] Acute ruptures often present with sudden onset of pain associated with a "snapping" or audible "pop" heard at the site of injury. Patients can describe the sensation of being kicked in the lower leg. The injury is causes significant pain and disability in patient populations. Achilles tendon injuries typically occur in individuals who are only active intermittently (i.e., the "weekend warrior" athletes). The injury is reportedly misdiagnosed as an ankle sprain in 20% to 25% of patients. Most commonly affected as 10% report a history of prodromal symptoms, and known risk factors include prior intratendinous degeneration, fluoroquinolone use, steroid injections, and inflammatory arthritides.[2,3]
Sexual Dysfunction with Risperidone in Male and Female Patients of Schizophrenia
Authors:   Consultant Psychiatrist, Guwahati, Bora Dr Malleeka
Published: May 2024

Background: Sexual side-effects due to use of Antipsychotic drugs have become one of the most important determinants of treatment compliance. Studies regarding sexual side-effects associated with antipsychotics comprise only a handful in the Indian population, especially so in this north-eastern part of the country. Aims and Objectives 1. To assess the sexual dysfunction associated with Risperidone in male and female patients of Schizophrenia. 2. To compare the sexual dysfunction associated with Risperidone between male and female patients of Schizophrenia. Materials and Methods: This was a hospital based comparative study conducted on 50 clinically stable male and female patients of Schizophrenia on Risperidone only. A Sexual Functioning Questionnaire (SFQ) was administered after assessing the clinical stabilities with the Brief Psychiatric Rating Scale (BPRS). Sexual dysfunction was assessed by calculating the mean scores on all the domains of sexual functioning in SFQ which were then compared across the study groups using the Chi square test . The results were analysed using SPSS Version 16.0 setting the significance threshold at p <0.05. Results: From this study, we inferred that with Risperidone, impairment is seen in desire disorders (12%), arousal disorders (14%), orgasmic difficulties (26%) and overall sexual dysfunction (20%) although not statistically significant. It was also found that in females, Risperidone caused more desire disorders, more arousal disorders and a more overall sexual dysfunction; whereas in case of males, Risperidone caused more arousal disorders, more orgasmic difficulties, more sex related pain problems and a more overall sexual dysfunction; Conclusion: Sexual dysfunction is an important side-effect of Antipsychotic drugs. So clinicians should try to address these side-effects to help patients’ attain a better compliance.
Infantile Fibrosarcoma Presenting as Neck Mass: A Case Report
Authors:   Consultant Pathologist, Department of Pathology, Tomo Riba Institute of Health and Medical Sciences, Naharlagun, Arunachal Pradesh, India, Tana Dr Yasap
Published: May 2024

Abstract A one year old boy presented with a mass in the posterior triangle of left side of neck for ten months with rapid increase in size since one month. Radio-imaging was done. He underwent surgery, the mass was excised and the histopathological examination was done. Clinically, it was thought to be as schwannoma. Tumor measured 10 x 8 x 6 cm approximately, fixed with underlying tissue, venous prominence seen on bosselated surface and was non-tender. Microscopically, showed a cellular neoplasm composed of spindle cells arranged in herringbone pattern, also as fascicles and bundles, with focal area showing slit like thin-walled vessels simulating hemangiopericytoma like vasculature. Focally, shows infiltration of muscle and fat. Immunohistochemistry study was performed. Correlating histology with clinical, radiology and immunohistochemistry findings, the patient was diagnosed as a case of Infantile Fibrosarcoma of neck region, a relatively rare malignant fibroblastic tumor, occurring mostly in infancy, often misdiagnosed with benign tumor. Keywords: Cellular, herringbone pattern, hemangiopericytoma, immunohistochemistry, fibroblastic.
Early Initiation of SGLT2 Inhibitor is Important Irrespective of Ejection Fraction
Authors:   Consultant Interventional Cardiologist, Department of Cardiology, AMRI Hospital, Saltlake, Kolkata, Ganguly Prof. Dr Kajal
Published: May 2024

Introduction Sodium Glucose Cotransporter inhibitor (SGLTi) has revolutionized the medical management of heart failure in the last decade. This molecule was initially described as a glucose-lowering agent but now it has been recommended in patients with chronic heart failure irrespective of ejection fraction and diabetic status. SGLT2 inhibitor reduces preload by natriuresis and diuresis, reduces afterload, decreases pulmonary artery pressure, improves myocardial energetics, and decreases myocardial fibrosis. It also reduces NTpro BNP levels in heart failure patients, decreases serum uric acid, and promotes weight loss. It has also been proposed that this molecule has a favorable effect on vascular remodeling. SGLT-2i improves cardiac output and attenuates maladaptive cardiac remodeling, chronic inflammation, oxidative stress, and endothelial dysfunction (ED) by restoring the activity of nitric oxide (NO) within the vascular endothelium. As was foreseeable this molecule became one of the foundation pillars in the management of heart failure with reduced as well as preserved ejection fraction. SGLT2i also has a reno-protective effect, particularly in patients with heart failure and diabetes. Evidence with SGLT2 inhibitor in Heart failure with preserved ejection fraction (HFpEF) DELIVER TRIAL has evaluated the effect of dapagliflozin on total (first and recurrent) heart failure events in patients with heart failure having preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF). A total of 6263 patients with LVEF of more than 40 %, NHYA Class II-IV, and high NT-pro BNP (>300pg/ml in sinus rhythm and > 600pg/ml in patients with atrial fibrillation) were included over the total study period of two years. Dapagliflozin 10 mg was compared to placebo. In patients with HFmrEF and HFpEF, dapagliflozin reduced the risk of total heart failure events and heart failurerelated hospital admissions. (1)
Emerging Hypertension in Young Adults: A Detailed Case Report on Takayasu Arteritis in a 29-Year-Old Female from South India
Authors:   Government Medical College, Trivandrum, Jossy Preeti Elizabeth
Published: May 2024

Abstract Introduction: Takayasu arteritis is a rare vasculitic disorder predominantly affecting young women, characterized by inflammation of the aorta and its major branches usually seen in the East Asian population. Due to its varied clinical presentation, early diagnosis remains challenging, necessitating a high index of suspicion. Case Report: A 29-year-old South Indian female presented with exertional dyspnea to the emergency department and was initially diagnosed and treated as middle lobe pneumonia. Further physical and laboratory evaluations done at that time were unremarkable. Following successful treatment, she remained largely asymptomatic and sought evaluation at the local clinic due to elevated blood pressure detected during home monitoring. On work up of hypertension Echocardiography was done which showed unusual wall thickening of the ascending aorta and mild aortic regurgitation .CT aortogram was then done which revealed aortic thickening and left renal artery stenosis. Confirmation of takayasu arteritis was achieved through PET-CT imaging at a higher tertiary care centre, leading to initiation of immunosuppressive therapy and subsequent percutaneous transluminal angioplasty stenting of the left renal artery. Conclusions: A high index of suspicion is crucial in young females with unusual presentations especially in the South Indian population where the disease is not prevalent. Due to financial constraints it is very likely that appropriate imaging is not done in cases where takayasu arteritis is not suspected by the treating physician. Lack of appropriate work up of hypertension can result in missed diagnoses which can lead to potentially disastrous side effects to the disease Keywords: Takayasu arteritis, young female, vasculitis, immunosuppressive therapy, angioplasty.
All-On-4 Implant with Hybrid Prosthesis Opposing Implant Supported Overdenture- A Case Report
Authors:   Professor and Head of Department, Department of Prosthodontics, Crown & Bridge, Pandit Deendayal Upadhyay Dental College & Hospital, Solapur, Maharashtra, Dixit Dr Santosh
Published: May 2024

Implant-supported prosthetic solutions have revolutionized the field of dental rehabilitation, particularly for patients with extensive edentulism or failing dentition. Among these, the All-on-4 implant technique has gained popularity due to its ability to provide and aesthetic restoration with fewer implants and reduced surgical complexity. However, challenges such as insufficient bone volume or poor bone quality in the edentulous maxilla or mandible may necessitate alternative approaches to ensure long-term success and patient satisfaction. One such approach involves the integration of a hybrid prosthesis with All-on-4 implant concept opposing an implant-supported overdenture. This hybrid solution combines the stability and support of dental implants with the comfort and versatility of removable prostheses, offering a balance between fixed and removable options. Key aspects covered include the selection of appropriate candidates for this treatment modality, diagnostic imaging techniques for precise implant placement, surgical protocols for achieving optimal osseointegration and soft tissue management, prosthetic fabrication processes including material selection and occlusal considerations, postoperative care and maintenance strategies to ensure long-term success. Through a comprehensive examination of current literature, clinical case studies, and expert opinions, this case report aims to provide clinicians with valuable insights into the rationale, planning, execution, and outcomes of utilizing a hybrid prosthesis with All-on-4 implant concept opposing an implant-supported overdenture. By understanding the indications, advantages, limitations, and clinical nuances of this treatment approach, dental professionals can effectively address the diverse needs and preferences of edentulous or near-edentulous patients, ultimately improving their quality of life and oral health outcomes. Keywords: All-on-4 implants, hybrid prosthesis, implant-supported overdenture, prosthetic rehabilitation, bone quality, patient satisfaction.
¿Que es el mito?
Authors: Sánchez Garrafa Rodolfo
Published: May 2024

No presenta resumen.
Estudiar el desarrollo discursivo: un enfoque socio-psico-discursivo
Authors: Shiro Martha
Published: May 2024

Objetivo: Ofrecer una propuesta metodológica en el campo de los estudios discursivos.
Originalidad: Una guía para sistematizar los pasos metodológicos que conducen a plantear un problema de investigación y a construir un esquema analítico en el campo de los estudios discursivos desde un enfoque socio-psico-discursivo.
Método: Reflexionar acerca de las decisiones metodológicas adoptadas en mi trayecto como investigadora e ilustrar con ejemplos tomados de uno de mis proyectos de investigación sobre desarrollo narrativo.
Estrategias de recolección de la información: Reseñar las publicaciones en las que se basan las reflexiones metodológicas presentadas aquí.
Conclusiones: Para que el planteamiento del problema y la construcción de un esquema analítico en un estudio relacionado con discurso tengan validez, es necesario seguir unos pasos cuidadosamente planificados y enmarcarlos en un marco teórico y metodológico relevante y compatible con el estudio.
Competencia discursiva estudiantil en la producción escrita del texto argumentativo académico: el caso de la Universidad Nacional Autónoma de Honduras-UNAH
Authors: Mondragón Hernández Janeth
Published: May 2024

Objetivo:  Develar la competencia en la producción del texto escrito argumentativo de los estudiantes de primer ingreso de la Universidad Nacional Autónoma de Honduras-UNAH en el primer periodo académico de 2018.
Originalidad/aporte: Su importancia radica en la necesidad de desarrollar un programa estratégico que permita la alfabetización académica desde los inicios de la Educación Superior, con el fin de que posteriormente los estudiantes puedan de manera autónoma continuar su proceso de cualificación. Asimismo, se busca que esta investigación constituya un aporte para mejorar la calidad de la Educación Superior, en principio, de manera específica en los espacios de aprendizaje del Departamento de Letras y por extensión en el largo plazo a las demás áreas académicas.
Método: Se ubica en el paradigma interpretativo, enfoque cualitativo. Muestra intencional. Para alcanzar los objetivos se llevó a cabo el análisis e interpretación de la microestructura, la superestructura y la macroestructura de la producción textual de los participantes.         
Estrategias/recolección de información:  Diseño aplicado: investigación acción, a través del cual se conformó un corpus de 150 ensayos argumentativos escritos por cincuenta estudiantes. De este se seleccionaron 30 escritos relevantes. La técnica para el análisis e interpretación de los escritos fue el análisis del discurso.
Conclusión: Los estudiantes no son usuarios competentes en la producción del texto académico argumentativo. Sus escritos presentan limitaciones, aunque también muchas potencialidades.
Origen de escuela lancasteriana en Colombia: historiografía y propósito de implementación en la Constitución de Cúcuta de 1821
Authors: Acevedo Tarazona Álvaro , Villamizar Palacios Carlos
Published: May 2024

Objetivo: Este artículo analiza la adopción y las dificultades de implementación del método lancasteriano en la naciente Colombia de 1821, conformada en su momento por las actuales Colombia, Ecuador y Venezuela.
Originalidad/aportes: Se busca explicar las dificultades de implementación del método a la luz de su contexto y en una relación comparada con la experiencia en otros países.
Método: El método lancasteriano promulgado en la Constitución de Villa del Rosario de Cúcuta y que nació como el hito más importante de escolarización obligatoria en América Latina, es analizado a la luz del contexto de la Ilustración y su interpretación política republicana en el continente, por medio de la revisión de fuente edita y documental.
Estrategias/recolección de información: La recolección de información se realizó a través de revisión documental de fuentes en línea, prensa y revisión de archivo, junto a una búsqueda bibliográfica de lo publicado sobre el tema.
Conclusiones: Al considerarse las intenciones de los legisladores por promulgar un Estado educador y las dificultades en la implementación del método lancasteriano en la Colombia de 1821, a propósito de otras experiencias de implementación en México y Perú, fue evidente el fracaso por la debilidad del propio Estado colombiano naciente y las constantes guerras e inestabilidad política.
primer rector de la universidad republicana en Venezuela: José María Vargas Ponce.
Authors: Mora García José Pascual
Published: May 2024

Objetivo: Nos proponemos como objetivo central develar los fundamentos de los Estatutos de la Universidad Central de Venezuela (1827), considerada la primera universidad republicana en Venezuela. La misma era sensuataria (sic) de la Real y Pontificia Universidad de Caracas (1721), con su herencia colonial del antiguo Colegio Santa Rosa de Lima de Caracas.
Metodología: Es un estudio que metodológicamente se nutre del paradigma historiográfica de la red Sociedad de Historia de la Educación Latinoamericana (Shela),  (Soto et Al, 2017).
Originalidad: En tal sentido, se busca elaborar un estudio sobre los Estatutos y mentalidad educativa, con documentos de “primera  mano”, arqueo documental y aplicación del método dialógico-crítico, descriptivo,  empoderado en los lineamientos de las epistemologías del sur.
Estrategia/Coleta de Datos. El estudio se sigue sobre las fuentes de las Actas del Claustro Pleno Universitario, entre otros puntos abordaremos: el estado del arte de la ciencia experimental; la relación de sanciones o castigos;  los compromisos de los estudiantes y los beneficios y normas; la eliminación de la figura del censor regio; la exoneración del servicio militar ara los estudiantes; la eliminación del prejuicio de la “limpieza de sangre” para ingresar a la universidad; el proceso de elección del primer rector republicano; las obras pías como escenarios para el sostenimiento de la universidad; el apoyo a la integridad de Colombia; la fundación de las cátedras para la enseñanza del inglés y francés; la consagración del derecho de jubilación de los profesores; la universidad velara como junta protectora del Colegio de Niñas Educandas; exoneración de los pagos para el derecho de grado, por parte del bachiller Medardo Medina, por ser de notoria pobreza;  entre otros aspectos que constan en sus Estatutos.
Conclusiones: la universidad republicaba se funda sobre los criterios de la ciencia moderna, los derechos establecidos en la Constitución de 1821, y los principios emergentes en materia laboral y la universidad. La formación intelectual y el espíritu civilista de venezolano, José María Vargas Ponce (1786-1854), como primer rector fue fundamental para aquilatar el centro de las Luces inspirada en el espíritu de la Ilustración.
Kiai Leadership Strategy in Building Organizational Commitment in Pesantren
Authors: Yadi Fajri  , Munirul Abidin  , Achmad Khudori Soleh
Published: May 2024

This research aims to analyze the strategy of kiai in building organizational commitment in Pesantren Al Islam Kemuja Bangka and Pesantren Daarul Abror Kace Bangka. These strategic steps included how kiai laid the foundation of its organization, established closeness with subordinates, built togetherness, and appreciated subordinates' performance. This research used a qualitative approach with a case study type. To obtain research data, researchers used in-depth interviews, observation and documentation methods. Data analysis began with data condensation, presentation and ended with drawing conclusions or verification. The results of this study showed that kiais' strategies n building organizational commitment in two pesantren were different and closely related to their leadership type. In detail, the Pesantren Al Islam Bangka was led by a spiritual kiai, so that in building the commitment of the caregiver organization began with orienting the mission of the pesantren to da'wah, approaching subordinates through inspiring examples, building togetherness through close and warm communication, and appreciating subordinates with an emotionally and spiritually supportive attitude. While at Pesantren Daarul Abror Bangka, it was led by visionary kiai who build the commitment of caregiver organizations by formulating the mission of the pesantren according to the wishes of subordinates, establishing relationships by creating commensurate organizational value, building togetherness through solid teamwork, and appreciating subordinates with full delegation of authority.
Using Tahsin Al-Qur’an Based on Self-Regulated Learning to Improve Students' Capabilities in Reading The Al-Qur’an
Authors: Suwarno  , Muhammad Hatta  , Mahdalena  , Muhammad Almi Hidayat
Published: May 2024

The purpose of this study was to determine the effectiveness of self-regulated learning-based tahsin Al-Qur'an in improving students' Al-Qur'an reading skills. The research method used was the quasi experimental method, the one group pretest-postest design. The experimental subjects in this study were 25 PGMI study program students in semester 3 of the 2022/2023 academic year. Research data were collected using tests in the form pre-test and post-test. Data analysis used statistical analysis with a paired sample t-test to determine the significance of the pre-test and post-test values. This research resulted in the finding that tahsin Al-Qur'an based on self-regulated learning could significantly improve students' Al-Qur'an reading ability. It could be seen from the paired sample t-test of 19.230 which was higher than the t-table of 2.064 (df 24) with a significant value of 0.000, which was lower than 0.05.