Correlation Between Mean Platelet Volume (MPV) and Clinical Outcome in Patients with Subdural Hemorrhage (SDH) in Prof. I.G.N.G Ngoerah General Hospital Denpasar
Authors: Wahyuni Setiawati Ni Made Rai , Widyantara I Wayan , Putri Laksmidewi Anak Agung Ayu 
Published: February 2023

Background: Subdural hemorrhage (SDH) occurs due to the accumulation of abnormal blood under the dura mater, a protective layer of brain tissue under the calvarium due to the rupture of the bridging veins. The importance of hematological factors as parameters related to intracranial bleeding, one of which is SDH. Mean Platelet Volume (MPV) is one of the main parameters that reflect the function and activity of platelets. The relationship between MPV values and the incidence and outcome of SDH is not fully known. This study aims to determine the relationship between MPV and SDH outcomes for monitoring and prognostic purposes for SDH.
Methods: This research is cross-sectional. This research was conducted based on data from medical records from inpatient installations at Prof. I.G.N.G Ngoerah General Hospital Denpasar with a total sample of 96 cases. The data included in the inclusion criteria were medical record data which contained information about research variables, which are gender, age, history of previous trauma, and the value of Mean Platelet Volume (MPV). This study included data on 96 patients with SDH who were admitted to the Inpatient Installation of Prof. I.G.N.G Ngoerah General Hospital from July 2018 to August 2021. All patients carried out routine blood tests in the first hours of hospitalization and the outcome was good (discharged alive) and poor (died) during hospitalization. The MPV value was converted into a nominal variable and its relationship with the outcome was assessed by bivariate analysis.
Results: From data collection, 96 patients with SDH were treated at the inpatient installation of Prof. I.G.N.G Ngoerah General Hospital during that period. Distribution of patients based on the history of trauma most of the patients had a history of previous trauma 57 patients (59.4%) and 39 patients (40.6%) from this study denied any trauma, based on gender, 67 patients were men (69.7%), 40 of whom had traumatic SDH and 27 others had non-traumatic SDH. There were 29 women with subdural hemorrhage (30.2%), with 17 having traumatic SDH and 12 having non-traumatic SDH. From the results, it was found that the age group of SDH patients ≤ 60 years, was 32 patients (33.3%), where most (18 patients) had Non-traumatic SDH and 14 patients experienced traumatic SDH. While the age group of 60 years and over was more than 64 patients (66.7%), with 21 of them experiencing non-traumatic SDH and 43 others experiencing traumatic SDH. The overall outcome was that 57 patients were discharged alive and 39 died during hospitalization. A bivariate analysis test with Chi square to find the relationship between abnormal MPV values with good and poor outcomes of SDH showed no significant relationship between the two variables (p = 1,000).
Conclusion: Based on the results of this study, the value of the Mean Platelet Volume was not significantly associated with the outcome in patients with Subdural hemorrhage.

Keywords: Subdural hemorrhage (SDH), Mean Platelet Volume (MPV), Outcome, prognosis