bluuebunny/crossref_metadata_2025 huggingface dataset:
Pathomorphological markers of recurrent uterine leiomyoma in reproductive age
Authors:   Peoples' Friendship University of Russia named after Patrice Lumumba, Karamian R.A. ,   Moscow, Russian Federation, Ordiyants I.M. ,   Peoples' Friendship University of Russia named after Patrice Lumumba; Moscow, Russian Federation, Demura T.A. ,   Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University); Moscow, Russian Federation, Krot M.A. ,   Peoples' Friendship University of Russia named after Patrice Lumumba; Moscow, Russian Federation
Published: February 2024

Aim. To determine the pathomorphological markers and clinical factors of recurrent uterine fibroids in reproductive age. Design. Prospective, non-randomized, longitudinal study. Materials and methods. The study included 75 patients, of whom 52 had uterine fibroids without recurrence (group I), 23 with relapse (group II). Indications for surgical treatment were: prolonged, heavy menstruation leading to anemia, pain syndrome, recurrent abnormal uterine bleeding, compression syndrome of adjacent organs. The study included patients with myomatous nodes of types 0–7 according to the FIGO (International Federation of Gynaecology and Obstetrics) classification. Results. During morphological examination, leiomyoma was macroscopically presented as a dense nodular formation with an uneven surface, whitish in color, and fibrous in appearance when cut. When comparing the size of the uterus (weeks of conditional pregnancy) in the comparison groups, it was revealed that in group I Me (Q1–Q2) was 13.00 (10.0–15.0), in group II - 13.0 (11.0–15.0) without statistically significant differences (p = 0.58). At the same time, in patients of group II with uterine sizes up to 10 weeks. – recurrence of uterine fibroids occurs in every fifth (21.7%), from 10 to 15 weeks. almost every second (60.9%) and more than 15 weeks. – every sixth (17.4%) (see diagram 1). As for the number of myomatous nodes, in group II, multiple uterine fibroids were detected in every second patient (60.9%). When comparing the growth rate of myomatous nodes in half (43.5%) of the examined women with relapse, their growth rate ranged from 6 months to 1 year, in every third (39.1%) — more than 1 year. Conclusion. According to our data, patients with recurrent uterine myoma have a number of clinical features compared to those with simple uterine myoma — younger age and duration of the disease. Recurrent uterine fibroids are characterized by rapid growth of myomatous nodes, large size and growth rate of nodes. Thus, understanding all of the mechanisms underlying leiomyoma through the integration of differential cellular/molecular characteristics may contribute to the discovery of tumor-specific biomarkers as well as the development of targeted therapeutic approaches that specifically target the affected pathways. Key words: uterine leyomioma, pathomorphology of uterine leyomioma, growth zones of leiomyoma.
Variants of fertility preservation in patients with borderline ovarian tumors
Authors:   Almazov National Medical Research Centre, Rassokha O.S. ,   Saint Petersburg, Russian Federation Saint Petersburg City Мultidisciplinary Hospital No. 2,   Saint Petersburg, Russian Federation, Tsypurdeeva A.A. ,   Almazov National Medical Research Centre; Saint Petersburg, Russian Federation,   The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; Saint Petersburg, Russian Federation, Mikhelashvili L.I. ,   Saint Petersburg University; Saint Petersburg, Russian Federation, Krylova N.Yu. ,   Saint Petersburg City Мultidisciplinary Hospital No. 2; Saint Petersburg, Russian Federation, Ulrikh E.A. ,   Almazov National Medical Research Centre; Saint Petersburg, Russian Federation, Zazerskaya I.E. ,   Almazov National Medical Research Centre; Saint Petersburg, Russian Federation
Published: February 2024

Aim: To study the main strategies for maintaining fertility in patients with borderline ovarian tumors (BOT). Key points. A detailed systematic analysis of modern domestic and foreign literature on BOT and preservation of fertility in patients was carried out. The study used data hosted on such electronic resources as eLIBRARY, Scopus, PubMed, MEDLINE, ScienceDirect and Cochrane Library (from January 2010 to 2022). This article discusses current views on the management of patients of reproductive age with BOT in order to implement the reproductive function. Since BOTs often develop in women of reproductive age, one of the main goals in their treatment is to preserve fertility, but with minimizing the risk of recurrence. Conclusion. One of the central tasks in the management of patients with BOT is the preservation of fertility. The key approaches to its solution are organ-preserving interventions (including conservative ones), cryopreservation of embryos, and the use of assisted reproductive technologies (ART). Nevertheless, taking into account the rather high risk of tumor recurrence, further studies are required to evaluate the efficacy and safety of ART in patients with BOT. Keywords: borderline ovarian tumors, tumors of potentially low malignancy, assisted reproductive technologies, fertility preservation.
Old uterine ruptures you need to know about
Authors:   Kazan State Medical University, Fatkullin I.F. ,   Kazan, Russian Federation
Published: February 2024

Aim: To review rare cases of uterine rupture that a practitioner may encounter. Key points. Uterine rupture is still a currently relevant issue. Despite the long history of its study and the gradual decrease in the incidence of such cases, uterine rupture remains one of the most severe manifestations of obstetric trauma. In most cases, without timely assistance, a patient with uterine rupture dies. However, there are situations that, seemingly, can be attributed to casuistry, but personal experience as an obstetrician-gynecologist in the 80-s of the last century in one of the African countries and communication with colleagues who had similar cases in their practice suggest the opposite. The article presents four clinical observations, when women lived for a long time with uterine rupture. Conclusion. When analyzing the clinical signs of uterine rupture which occurred during childbirth, attention should be paid to such a pathognomonic sign as termination of labor activity. This symptom has no other explanation than complete uterine rupture, and should be taken into account when monitoring women in labor, even if the pain syndrome is not pronounced, and hemorrhagic shock has not occurred. Keywords: uterine rupture, clinical signs, diagnosis.
A clinical case of diagnosis and complex treatment of endometriosis in a patient with infertility
Authors:   Almazov National Medical Research Centre, Efimova A.A. ,   Saint Petersburg, Russian Federation, Gorelova I.V. ,   Almazov National Medical Research Centre; Saint Petersburg, Russian Federation,   Delta Fertility Clinic; Saint Petersburg, Russian Federation, Makolkin A.A. ,   Delta Fertility Clinic; Saint Petersburg, Russian Federation, Sergienya O.V. ,   Almazov National Medical Research Centre; Saint Petersburg, Russian Federation, Zazerskaya I.E. ,   Almazov National Medical Research Centre; Saint Petersburg, Russian Federation
Published: February 2024

The purpose of the article: to present a clinical case of diagnosis and complex treatment of endometriosis in a patient with infertility. Key points: the problem of infertility associated with endometriosis is extremely relevant. An important direction is the search for the most effective non-invasive method for diagnosing endometriosis, because performing laparoscopy only for diagnostic purposes leads to an increase in the number of unnecessary surgical interventions. The formation of a unified management strategy for patients with endometriosis is another task that reproductive medicine specialists face. Treatment of infertility and pain in endometriosis cannot always be carried out simultaneously. Conclusion. Magnetic resonance imaging (MRI) can be a key method of non-invasive diagnosis of endometriosis. An integrated approach to the treatment of infertility and endometriosis allows to determine the tactics, stop the pain syndrome, and achieve the desired pregnancy. Key words: clinical case, endometriosis, infertility treatment, reproductive medicine, ART.
Influence of the Contractor's Culture on the UAE Construction Project's Performance
Authors: Mohammed Adel Khalifa , Bin Ishak Md. Sayuti
Published: February 2024

Academics have recently paid a lot of attention to culture, as it has been shown to have an impact on organizational performance. There has been little research carried out on assessing the correlation between project organizational culture and performance in the industry of construction. This study aims to verify how the culture of the contractor affects the construction projects performance in the UAE according to work practices at the project level. Data from 124 recently completed construction projects in the UAE were examined using questionnaires to collect specific data for this purpose. This study found a significant relationship between the contractor's culture and the project's performance. The findings reveal that the contractor significantly affects the overall performance of the project. Client satisfaction with quality is more impacted by the contractor's culture, while contractor satisfaction with profitability is least impacted by the contractor's culture. The findings of this study will assist those who work in construction projects in identifying ways to enhance the culture of the contractor at the project level. This can help improve the performance and success of construction projects.
БІОХІМІЧНІ ПОКАЗНИКИ КРОВІ НА ФОНІ ХРОНІЧНОГО ПІЄЛОНЕФРИТУ
Authors: Sheiko V. , Anisov I.
Published: February 2024

Медико-біологічними дослідженнями доведено, що до 40-річного віку у людини нирки зазвичай вже втрачають близько 40 % своїх функціональних можливостей. Це означає значну втрату здатності організму “фільтрувати” токсини і виводити їх з організму. Захворювання нирок – це захворювання, пов’язані з патологічними змінами в органах сечостатевої системи. Частіше зустрічаються: запальні захворювання нирок (пієлонефрит, піонефроз, туберкульоз нирки), сечового міхура (цистит), сечовипускального каналу (уретрит). Хвороби нирок часто мають безсимптомний перебіг патологічного процесу. Тому більшість людей звертають увагу, коли вже з’являються симптоми патології, що розвивається, і процес переходить в хронічний. Пієлонефрит і сечокам’яна хвороба складають до 70 % всієї урологічної патології. Ці захворювання з різною частотою зустрічаються у всіх вікових групах. Жінки 30-40 років страждають пієлонефритами в 4–5 разів частіше, ніж чоловіки, що обумовлене анатомічними особливостями будови і розташування жіночої уретри. За даними патологоанатомічної статистики, пієлонефрити виявляються до 20 % всіх розтинів, хоча за життя цей діагноз був встановлений не більше ніж в 1/4 частини хворих. 25 % людей, що перенесли гострий пієлонефрит, через 2–2,5 роки встановлюють хронічну форму захворювання. Метою нашого дослідження є вивчення біохімічних та клінічних показників крові на фоні хронічного пієлонефриту у жінок 22–35 років. На тлі хронічного пієлонефриту у жінок спостерігається достовірне підвищення вмісту загального білірубіну, креатиніну, сечовини та показника тимолової проби, що вказує на наявність запального процесу та порушення функціонування нирок. В периферійній крові спостерігається лейкоцитоз за рахунок збільшення нейтрофілів та моноцитів, що також вказує на запальний процес. Особливу увагу слід звернути, що майже всі показники периферійної крові жінок, які страждають на хронічний пієлонефрит, значно перебільшують такі показники практично здорових жінок, але при цьому вони знаходяться на верхній межі клінічних референтних показників.
US military spending: the real size and reasons for the overstatement
Authors: Anureev Sergey V.
Published: February 2024

Department of Defence (DoD) spending has decreased by 1.9-2.2 times relative to GDP and population growth since 1986, as well as the amount of military stocks and their annual purchases. The gap in military spending with Russia reduces from a nominal 12 times to a real 2.2 times by the adjusted purchasing power of currencies and share of real production in GDP. Total military, social, interest and allied payments for the US military are twice the budget of DoD, reaching $1574 billion in 2022. Social programs consume 38%, contractors get 30%, military personnel - only 4,6%, utilities - 4,3% from that total. DoD, the military-industrial companies and subcontractors employ 8,4 mln. people, DoD pays for 8,2 mln veterans and retirees, totally 6,4% of adults. 93% of the military locate in the US and support the local economy. DoD secures national industry and financial sector. Half of the military falls on the army and marines, of which ¼ are combat units, ¾ are support and management units, only 190 k. are the field combat personnel. Contractors spent half of overseas contingency operations fund, profits and inefficiencies account for 10 and 30% of total contracts, 30-45% of the contracts are without fixed price and competition.
Expert System for Supporting the Construction of Three-Dimensional Models of Objects by the Photogrammetry Method
Authors: Balovsyak Serhiy , Vasiliev Vladyslav , Fodchuk Ihor
Published: February 2024

The task of building high-quality three-dimensional (3D) models of objects is relevant, since such 3D models are widely used in various fields of science, technology and medicine. In this work, the construction of 3D models is performed by the photogrammetry method, which consists in the construction of a 3D model of an object based on a series of its photographs. The advantages of the photogrammetry method are low hardware requirements and relatively high accuracy. To build 3D models of objects by photogrammetry, the 3DF Zephyr program was used, which contains a set of tools for pre-processing images, reconstructing 3D models, editing and measuring the dimensions of 3D models, and exporting the obtained models. The principles of building three-dimensional models of objects by the method of photogrammetry based on initial images are considered. The main stages of building 3D models are described: calculation of sparse point cloud, key points, dense point cloud, polygon grid, texture grid. Model parameters are also edited and analyzed. An expert system was developed in the CLIPS environment to select the correct modes for building a 3D model. The knowledge base of the expert system contains production rules that allow you to establish the correct modes of building a 3D model based on the initial facts. 30 facts-conditions have been developed that describe the conditions for building a three-dimensional model. 20 facts-consequences and 15 facts-recommendations for building a 3D model have been developed. Using the developed rules, 36 production rules were built. Experimental verification of the developed system was carried out. Three-dimensional models of objects were built using the 3DF Zephyr program. After entering the facts that describe the process of obtaining the model into the expert system, a number of recommendations were obtained, in particular, to increase the area of textured surfaces and use uniform lighting of objects. After following these recommendations, the model was built with satisfactory accuracy.
UAV Integration with Neural Network in Landmine and Minefield Detection Tasks
Authors: Kasianchuk Artem , Lastivka Halyna
Published: February 2024

One of the newest stages in the improvement of unmanned aerial vehicles (UAVs) is the integration of such systems with the neural networks, which, in turn, is not a novelty, but provides such systems with a further level of practical application. Having conducted a meta-analysis of the results of previous studies and available information on this topic, it was found that in the modern period, in addition to successful practical implementations of the integration of artificial intelligence with UAVs, there is already a certain classification of such processes according to the principles of optimal improvement of UAV capabilities and by areas of society. In addition to the publicly available and well-known information about the successful use of drones in the military and logistics sectors of human activity, UAVs successfully perform tasks in such sectors as agriculture, engineering, search, etc. The main purpose of the article is to analyze, review, study and systematize existing information on the positive effectiveness and feasibility of using the principles, approaches and integration of unmanned aerial vehicles with machine learning technologies to improve the efficiency of solving the problems of locating and detecting landmines and minefields, which is a major humanitarian problem for civil society located in the territory where military conflicts are currently taking place or in the territories where military clashes or conflicts have occurred in the past. In this article, a small study was conducted to develop a prototype neural network that can be further integrated with UAVs for landmine and minefield detection tasks. The described neural network was trained on an open dataset, trained using the algorithms chosen in the study, and has a fairly good final result in terms of detection accuracy, which is 1.5% higher than the accuracy of publicly available neural networks in a review of similar developments or studies.
Keterampilan menulis teks persuasi siswa sekolah menengah pertama (SMP): apakah efektif menggunakan media iklan dan media karikatur?
Authors: Nurhadi Dewi , Hamsa Akmal , Ramly Ramly
Published: February 2024

Penelitian ini menggunakan jenis penelitian kuantitatif yang bertujuan untuk (1) mengkaji keterampilan menulis teks persuasi siswa SMP dalam  menggunakan media iklan dan media karikatur; dan (2) membuktikan keefektifan penggunaan media iklan dan kakarikatur dalam  meningkatkan ketrampilan menulis teks persuasi siswa  SMP. Penelitian ini menggunakan Quasi Eksperimen bentuk desain Nonequivalent Control Group Design. Populasi penelitian ini adalah seluruh siswa Kelas VIII SMP Negeri 2 Binamu. Penarikan sampel dilakukan dengan menggunakan teknik simple random sampling dengan penentuan sampel secara acak. Sampel yang terpilih, yaitu Kelas VIII3 dengan menggunakan media iklan dan Kelas VIII1 dengan menggunakan media karikatur. Instrumen yang digunakan dalam penelitian ini berupa tugas menulis teks persuasi dengan pengumpulan data, yaitu pemberian tugas. Data yang terkumpul kemudian dianalisis dengan menggunakan statistik deskriptif dan statistik inferensial menggunakan bantuan SPSS version 20. Hasil penelitian menunjukkan bahwa (1) keterampilan menulis teks persuasi dengan menggunakan media iklan siswa Kelas VIII3 SMP Negeri 2 Binamu berada pada kategori terampil dengan nilai rata-rata 73,65; (2) keterampilan menulis teks persuasi dengan menggunakan media karikatur siswa Kelas VIII1 SMP Negeri 2 Binamu berada pada kategori cukup terampil dengan nilai rata-rata 60,81; dan (3) keterampilan menulis teks persuasi dengan menggunakan media iklan lebih efektif daripada media karikatur. Hal ini ditunjukkan dari hasil analisis data, diperoleh nilai thitung sebesar 3,214 dan nilai ttabel 1,993. Sehingga, dinyatakan bahwa nilai thitung > ttabel, maka hipotesis alternatif (H1) diterima. Artinya, media iklan lebih efektif daripada media karikatur dan hipotesis nol (H0) ditolak.
Pendapatan Pajak: Apakah Terdapat Perbedaan pada Masa Covid-19 dan Pasca Covid-19?
Authors: Djamaluddin Nurulnisa , Hadi Dudi Abdul
Published: February 2024

Covid-19 telah mendorong adanya perubahan di berbagai sektor. Salah satu sektor yang terdampak yakni terkait dengan pendapat dari pajak kendaran bermotor di Sulawesi Tengah. Berdasarkan hal itu, penelitian ini bertujuan untuk menganalisis perbedaan penerimaan pajak kendaran baik di masa COVID-19 maupun pasca COVID-19. Untuk mengukap tujuan tersebut, penelitian ini menggunakan pendekatan kuantitatif dengan desain ex post facto. Data pada penelitian ini diambil dari informasi penerimaan pajak kendaraan angkutan bermotor bulanan dari Badan Pendapatan Daerah (BAPENDA) Provinsi Sulawesi Tengah antara tahun 2020 dan 2022. Selain itu, peneliti juga melakukan observasi secara langsung. Selanjutnya, data dari hasil pengumpulan di analisis secara deskriptif maupun secara kuantiatif menggunakan Anova dan paired sample t-tes. Berdasarkan hasil penelitian terdapat Perbedaan Pendapatan Pajak Kendaraan Bermotor pada Masa Covid-19 dan Masa New Normal di Kantor dinas Badan Pendapatan Daerah (BAPENDA) Provinsi Sulawesi Tengah. Kebijakan pada Masa New Normal mampu meningkatkan total pendapatan pajak kendaraan bermotor (PKB) dibandingkan pada masa pandemi covid 19, yaitu pada Juli 2021 sampai Oktober 2022.
Strategi promosi Pondok Pesantren Darul Maarif Indramayu di era digital: explorative case study
Authors: Apriyanto Ade , Subaweh Ahmad Maskur , Setiawardani Wawan
Published: February 2024

Penelitian ini bertujuan untuk mengungkap kegiatan promosi, mengetahui strategi promosi, dan mengetahui bauran-bauran promosi (promotion mix) yang handal diterapkan pondok pesantren Darul Ma’arif Indramayu di era digital. Penelitian ini menggunakan metode kualitatif. Pendekatan penelitian ini adalah studi kasus. Strategi penelitian studi kasus adalah strategi dimana peneliti menyelidi secara cermat suatu program, peristiwa, aktivitas, atau sekelompok individu. Teknik pengumpulan data yang digunakan pada penelitian ini adalah observasi (pengamatan), interview (wawancara), dokumentasi, dan gabungan (triangulasi). Hasil penelitian ini yaitu strategi promosi pondok pesantren Darul Maarif Indramayu di era digital adalah merencanaan dengan matang dengan cara melakukan menganalisis audien sasaran dan menetapkan tujuan promosi. Sasaran audien yang dituju adalah khalayak umum, lebih khusus orang tua yang memiliki anak ingin melanjutkan tingkat SMP dan SMA. Sedangkan tujuan promosi yang ditetapkan adalah ingin meningkatkan citra (image) pesantren dengan menyebarluaskan keunggulan program-program pendidikan, fasilitas-fasilitas terbaik, dan prestasi-prestasi yang didapat melalui bauran-bauran promosi (promotions mix) melaui media digital seperti facebook, youtube, instagram, twitter, tiktok, podcast, dan website. Setiap media digital tersebut ditangai oleh tim khusus. Selain gencar menggunakan media komunikasi promosi digital, pesantren Darul Maarif juga masih menerapkan bauran promosi konvensional seperti periklanan melalui radio, mengadakan diskon-diskon menarik, mengadakan berbagai kegiatan lomba, dan kegiatan sosial yang melibatkan masyarakat sekitar
Nanopartikel ekstrak etil asetat daun melinjo (gnetum gnemon l.) dengan aktivitas antioksidan dan antibakteri terhadap propionibacterium acnes
Authors: Puspitasari Ranny , Rahmat Deni , Djamil Ratna
Published: February 2024

Melinjo (Gnetum gnemon L) mengandung  asam  askorbat,  tokoferol, dan  polifenol (fenol sederhana, flavonoid, dan tanin. Senyawa kimia ekstrak G. gnemon diperoleh tiga senyawa yaitu 3,4-dimethoxychlorogenic acid, resveratrol, dan 3-methoxyresveratrol. Daun G. Gnemon memiliki potensi antioksidan dan antibakteri.  Tujuan penelitian ini membuat ekstrak dan nanopartikel ekstrak daun G, gnemon, serta mengetahui aktivitas antioksidan, antibakteri terhadap bakteri Propionibacterium acnes. Ekstraksi dilakukan dengan metode kinetik dengan pelarut etil asetat. Metode yang digunakan untuk pembuatan nanopartikel yaitu metode gelasi ionik dengan kitosan-Na TPP. Uji aktivitas antioksidan dengan metode DPPH dan uji akstivitas antibakteri menggunakan metode difusi cakram. Hasil menunjukkan ekstrak daun G gnemon memiliki aktivitas antioksidan lebih baik dibandingkan nanopartikel ekstrak daun G gnemon dimana nilai IC50 masing-masing sebesar 35,602 dan 55,105 ppm. Sedangkan untuk aktivitas antibakteri nanopartikel ekstrak G gnemon lebih kuat dibandingkan ekstrak daun G gnemon dimana zona hambat sebesar 12,3 mm. Analisis data dengan uji Mann-Whitney menunjukkan nilai Asymp Sig (2-tailed) < 0,05 terdapat perbedaan yang signifikan. Ukuran partikel Nanopartikel ekstrak daun G. gnemon yaitu (419,4 mm), indeks pendispersi (0,572%) dan potensi zeta (-68,5 9 mV). Ukuran nanopartikel memenuhi syarat karena <1000 mm
Pengaruh payables deferral period, inventory conversion period, average collection period, dan cash conversion cycle terhadap profitabilitasperusahaan manufaktur
Authors: Sarbini Sarbini , Herliansyah Yudhi
Published: February 2024

Tujuan penelitian ini adalah untuk menganalisis kinerja keuangan perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia tahun 2016-2019 dalam kaitannya dengan payables deferral period, inventory conversion period, average collection period, dan cash conversion cycle. Data sekunder digunakan untuk penelitian ini. Berbagai sumber online, antara lain situs perusahaan, situs emiten, dan laporan tahunan yang dimuat di IDX.co.id, digali untuk mendapatkan informasi. Kami memilih 46 perusahaan unik untuk dianalisis menggunakan campuran sampel acak dan teknik Slovin. Untuk melakukan analisis statistik, kami menggunakan E-Views 10.0. Beberapa faktor ditemukan untuk mempengaruhi profitabilitas. Faktor-faktor ini termasuk lamanya waktu yang dibutuhkan untuk mengkonversi hutang, mengkonversi persediaan, mengumpulkan pembayaran rata-rata, dan mengkonversi uang tunai. siklus pengumpulan data dapat diabaikan. Efisiensi dimana manajemen mengalokasikan modal kerja merupakan indikator kaliber keputusan mereka. Memasukkan kerangka pengambilan keputusan ini memungkinkan bisnis untuk membuat strategi yang meningkatkan hasil bottom-line sambil tetap memenuhi kebutuhan pemegang saham dan pemangku kepentingan lainnya
Pengaruh Citra Merek Dan Kualitas Pelayanan Terhadap Kepuasan Konsumen Serta Dampaknya Terhadap Loyalitas Konsumen Produk Indihome
Authors: Budiman Alvin Yonatan , Karnadi Marcellia Susan
Published: February 2024

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh citra merek dan kualitas pelayanan terhadap kepuasan konsumen serta dampaknya terhadap loyalitas konsumen produk IndiHome PT Telkom di Kota Bandung. Metode penelitian ini menggunakan pendekatan kuantitatif dengan menggunakan analisis deskriptif dan analisis verifikatif. Analisis verifikatif yang digunakan adalah analisis jalur (path analysis). Pengumpulan data penelitian ini menggunakan kuesioner. Sampel penelitian ini sebanyak 100 orang. Teknik pengambilan sampel yang digunakan adalah purposive sampling. Penelitian ini menggunakan tiga variabel yaitu variabel independen (citraλmerek dan kualitas pelayanan), variabel intervening (kepuasan konsumen), dan variabel dependen (loyalitas konsumen). Penelitian ini menggunakan alat analisis dengan program SPSS versi 23. Hasil analisis desktiptif menunjukkan bahwa secara keseluruhan citra merek, kualitas pelayanan, kepuasan konsumen, dan loyalitas konsumen masih termasuk dalam kategori cukup. Hasil pengujian hipotesis menunjukkan bahwa pada substruktur pertama citra merek, kualitas pelayanan memiliki pengaruh positif dan signifikan terhadap kepuasan konsumen secara baik simultan maupun parsial, dengan memberikan pengaruh sebesar 93,8%. Selain itu, berdasarkan pengujian hipotesis substruktur kedua diperoleh bahwa citra merek, kualitas pelayanan memiliki pengaruh positif dan signifikan terhadap loyalitas konsumen secara baik simultan maupun parsial dengan memberikan pengaruh sebesar 90,8%. Hasil pengujian substruktur ketiga menunjukkan bahwa kepuasan konsumen memiliki pengaruh positif dan signifikan terhadap loyalitas, dengan memberikan pengaruh sebesar 91,5%. Selain itu terdapat pengaruh yang signifikan antara citra merek dan kualitas pelayanan terhadap loyalitas melalui kepuasan konsumen.
Hakekat konsep pengaturan akuisisi saham perseroan terbatas berdasarkan keadilan dan kepastian hukum
Authors: Adhimastha Bayu , Kagramanto Budi , Prasetyowati Endang
Published: February 2024

Akuisisi merupakan pengambilalihan suatu perusahaan oleh perusahaan lain yang dapat dilakukan dengan mengambilalih aset suatu perusahaan dan/atau dengan mengambilalih saham dari perusahaan lain. Larangan terhadap kegiatan ini ditujukan terhadap praktek akuisisi yang terjadi di setiap level perdagangan atau sektor industri yang dapat mengakibatkan terjadinya hambatan terhadap persaingan usaha dan terjadinya praktek monopoli. Pasal 29 Undang-Undang No. 5 Tahun 1999 Tentang Larangan praktek monopoli dan persaingan usaha tidak sehat menetapkan bahwa penggabungan atau peleburan badan usaha atau pengambilalihan yang mengakibatkan nilai aset dan nilai penjualannya melebihi jumlah tertentu. Tindakan akuisisi dalam hal ini adalah untuk menciptakan konsentrasi pasar yang dapat mengakibatkan harga produk semakin tinggi dengan melihat produk pada pasar yang bersangkutan serta berapa besar pangsa pasar yang dikuasi oleh perusahaan tersebut. Kemudian untuk menambah kekuatan pasar (market power) menjadi semakin besar yang dapat mengancam para pesaing dari perusahaan tersebut. Pengaturan mengenai Akuisisi diperjelas dengan adanya peraturan komisi pengawas persaingan usaha (KPPU) No. 1 tahun 2009 mengenai pranotifikasi penggabungan, peleburan dan pengambilalihan. Serta dengan adanya Peraturan Pemerintah No. 57 Tahun 2010 tentang Penggabungan atau peleburan serta pengambilalihan saham perusahaan yang dapat mengakibatkan terjadinya praktik monopoli dan persaingan usaha tidak sehat dan juga Peraturan Pemerintah No. 44 Tahun 2021 tentang Pelaksanaan Larangan Praktek Monopoli dan Persaingan Usaha Tidak Sehat. Penelitian ini juga dilatarbelakangi dengan adanya kekaburan hukum di dalam Undang-Undang No. 40 Tahun 2007 Tentang Perseroan Terbatas oleh karena tidak terdapat suatu aturan yang menjelaskan secara tegas dan pasti tentang akuisisi itu sendiri, sehingga menimbulkan celah hukum di Indonesia.
Analisis kebutuhan pengembangan silabus pembelajaran bahasa Jawa Banten dengan pendekatan Content and Language Integrated Learning (CLIL)
Authors: Asdarina Asdarina , Baqiyah Suhanul , Permana Septi Citra , Hufad Achmad , Fathurohman Maman
Published: February 2024

Tujuan penelitian ini adalah untuk menganalisis kebutuhan pada silabus mata pelajaran Bahasa Jawa Banten di Kota Serang. Metode yang digunakan yaitu menggunakan penelitian deskriptif kualitatif. Teknik pengumpulan data yang digunakan adalah observasi dan wawancara. Sementara analisis data penelitian menggunakan pendekatan Miles et al dengan tahapan yakni pemilihan data, pengkajian, verifikasi dan penarikan kesimpulan. Penelitian ini memperoleh simpulan bahwa 1) analisis silabus, hanya ada beberapa KD yang tidak sesuai dengan sub tema serta pemakaian indikator yang diulang. Materi yang digunakan dalam pembelajaran tidak berdasarkan pada Budaya Lokal Banten, yakni menggunakan budaya daerah lain, 2) analisis siswa diperoleh kesimpulan bahwa siswa kurang mengenali budaya dan wilayah daerah sendiri yaitu daerah Banten sebagai tempat tinggalnya, 3) analisis guru membutuhkan silabus yang dapat memenuhi kebutuhan belajar secara individu dan mampu membuat siswa lebih mandiri sesuai dengan budaya lingkungan sekitarnya, 4) alasan pengembangan Silabus pembelajaran dengan pendekatan Conten Language and Integrated Learning (CLIL) dibutuhkan karena kenyataan di lapangan menunjukkan bahwa efek lingkungan luar terhadap siswa memiliki pengaruh yang besar
MODEL BISNIS PLAN DAN DAYA SAING UMKM MELALUI STRATEGI PEMASARAN PRODUK TERASI BAWANG DI INDRAMAYU
Authors: Nurpratama Meddy , Yudianto Agus
Published: February 2024

The research entitled Behavioral model of MSME Processing Processed Onions and Tersi, Indramayu Regency. The purpose of this research is to explore and analyze the behavior of MSME actors processing agricultural products in Indramayu district and how the efforts are being made with business continuity MSME actors can apply or implement a business plan planning model, SWOT analysis, in dealing with business competition. The data collection method was carried out using interview techniques which were equipped with a semi-structured list of questions. The questionnaire was used as a guide so that interviews were more structured and standardized. The analysis technique that will be used is the concept of SWOT analysis is the concept of seeking analysis to determine a decision on a problem. SWOT itself is an acronym for Strength, Weakness, Opportunity, Treats. The term analysis of strengths and opportunities in preparing a business plan or and looking for weaknesses and strengths because in this concept all processes are carried out carefully and identify as much detail as possible so that decisions taken are effective and able to have a significant impact on dealing with problems
Research on Innovative Design Method and Evaluation of Jewelry Based on CiteSpace&Playgound AI
Authors: Hu Jinhong , Yu Shuwei , Zhang Ming , Wu Yue , Lu Jinwei , Weng Jiongzhou , Liu Feiyang , Huo Hao , Li Cheng , Pan Dongfang
Published: February 2024

This study aims to propose an innovative jewelry design method that combines knowledge graph with artificial intelligence to solve the problem of relying on the experience of designers in the traditional jewelry design field, resulting in unstable design quality, difficulty in inheriting experience, and inability to evaluate innovation. The specific method is to extract research hotspots in jewelry design from the knowledge graph, and construct artificial intelligence recognizable prompt words based on the rules of prompt word formation. Use prompt words in artificial intelligence tools to generate ideas, then use AHP Analytic Hierarchy Process to screen the best ideas, and finally combine the designer’s ability to output design solutions. The combination of knowledge graph and artificial intelligence can affect the working methods and efficiency in the field of jewelry design, improve design quality and innovation, and solve the problem of inheriting design experience, which is of great significance for modern jewelry design.
“Ask Aloud Protocol”: Toward a Participant-Driven Question-Asking Design Research Method
Authors: Tang Lintao , Wang Sihang
Published: February 2024

In the field of problem formulation for design research, the conventional Think Aloud Protocol (TAP) has faced challenges in addressing complex problems such as Wicked Problems (WPs) over its two-decade history. Instead, the utilization of questions as a verbal tool has emerged as a more effective approach, producing insightful outcomes for intricate design challenges. Moreover, the largely untapped potential of participant-generated questions in design research holds promise for reducing subjective biases in designer-driven problem formulations and strengthening the role of participants. This study presents the Participant-Driven Ask Aloud Protocol (AAP) and employs it in spatial planning experiments at both QILI South Urban Village and the China World Mall’s Transit-Oriented Development (TOD) in Beijing, China. The analysis highlights AAP’s effectiveness in broadening the scope of generative design possibilities and facilitating a more precise and efficient identification of WPs in the design process.
Research on Improving the Quality of Japanese Chinese Machine Translation Based on Deep Learning
Authors: Lu Jialing , Yin Fengxian
Published: February 2024

In order to improve the quality of Japanese-Chinese machine translation, the research on improving the quality of Japanese-Chinese machine translation based on deep learning is put forward. The maximum entropy model is used to effectively classify Japanese possible states and passive states, and then the features of Japanese possible states and passive states are effectively integrated into the log-linear model to improve the translation model, so as to improve the accuracy of selecting possible states and passive states in translation rules. The experimental results show that this method can effectively improve the translation quality of Japanese possible sentences and passive sentences. On large-scale Japanese Chinese materials, the maximum translation BLEU value can be increased from 41.50 to 42.01, and the overall intelligibility of translation results has been improved by 2.71% in manual evaluation. Conclusion: This method can improve the accuracy of rule selection.
Computer-Aided Putonghua Test: Problems and Strategies
Authors: Song Yuhan
Published: February 2024

The implementation of mandarin test is one of the most important measures to popularize Putonghua in China. With the rapid development of modern information technology, especially the effective integration of computer, network and speech recognition technology, the model of computer-aided Putonghua proficiency test was born in a new form, which provides a good opportunity to promote the standardization and modernization of Putonghua proficiency test. Based on a brief introduction of the advantages of computer-aided Putonghua test, this paper mainly discusses the typical problems in the process of Putonghua test, and then puts forward the corresponding solutions in order to better promote the development of this test.
Research on Automotive Front Face Styling Based on Shape Grammar
Authors: Liu Lingling , Ma Biao , Pan Mengyuan , Chen Zhen , Yang Zeyu , He Xinyao
Published: February 2024

Automotive front face styling design needs to satisfy both innovative aesthetics and the recognition of brand identity. Under the dual drivers and constraints, this research focuses on the design method for inheriting brand identity in automotive front face styling. A design process combining shape grammar and product family DNA is proposed. The Audi sedan series front face is selected as the research object. Firstly, the dominant styling features and implicit design intentions of the brand DNA are extracted, and a mapping is established between the two. Then, the initial shape is determined based on user expectations and constraints. Finally, suitable grammar rules are selected based on shape grammar theory to derive and generate design solutions. The automotive front face styling designed through this method exhibits excellent brand recognition and matches the users’ design intentions. This design process can effectively reduce deviations between conceptual design and final products in the early stage of automotive front face styling design, minimize repetitive design, and thus shorten the development cycle, reduce costs, and enhance market competitiveness.
Application Research of Waterborne Plastic Waste Recycling Device Based on Green Design Principles
Authors: Li Zheng , Li Biao
Published: February 2024

In light of the severe plastic pollution in water bodies, this paper designs a plastic waste recycling device based on the “green design principles” to address the issue of plastic debris in inland waterways. This approach aims to tackle the problem of plastic waste entering the oceans at its source. The overall structure of the device incorporates an environmental recognition system, a green product system, and an interactive system. These systems encompass regional environmental awareness, integrated product design awareness, modularization awareness, and more to adhere to the “3R” principles of green design, effectively addressing the problem of plastic pollution in water bodies.
Product Innovation Design Method Based on System Thinking
Authors: Ye Dehui , Meng Lingxiao , Zhang Ruikai
Published: February 2024

Aim To propose a product innovation design method based on system thinking. In the conceptual construction stage of product design, in view of the lack of integrity and innovation of design, we use product system thinking to build a combination of innovative design methods to stimulate the design ideas and inspiration of designers, and then better carry out product innovative design. Methods From the four dimensions of social, environmental, human and product in product system thinking, we constructed a combined innovation system of elements, concreted the design elements and substituted them into the combined innovation model, extracted the final design keywords through random shuffling and reorganization, and finally analyzed the acquired terms for design translation, so as to break through the design thinking pattern and establish the innovative design scheme. Results Based on the product system thinking, a new design innovation thinking method was constructed. The design scheme was highly innovative, the element positioning was clear and clear, the method was feasible, and it met the theoretical and practical needs. Conclusion The product innovative design method based on system thinking, taking the specific design practice as an example, has verified the effectiveness of this method, which makes the innovative scheme produce rapidly and have the design systematism at the same time, which opens up the design idea and improves the design originality and innovation.
Artificial Intelligence Driven Promotion of Cultural Heritage Protection in the Context of Harmony Rural Construction
Authors: Wu Xiujuan
Published: February 2024

In order to use digital technology to protect intangible cultural heritage and regional culture, the innovative digital design of intangible cultural heritage is put forward from the perspective of Internet. This paper puts forward a collaborative innovative design method of “root carving technology+digitalization”. Taking “Zhu Zhanghuis lecture” in Yuelu Academy as the representative, this paper explores the innovative methods of developing scene-based root carving products by regional culture. The results show that the acceptance of using light-cured resin as the accessory of root carving is not high, and the proportion of people in the industry who appreciate or accept it is only 71.3%. Developing the design around the basic model is conducive to improving production efficiency, ensuring the improvement of efficiency while retaining the uniqueness of hand-made. The whole root carving product has a certain artistic conception, and can appreciate the connection with the concept of time, but the specific story can be strengthened. Conclusion: Integrating the situational story method into the root carving design of Hunan School can enhance the overall atmosphere and story of the root carving works, enhance the story of the root carving cultural and creative products of Yuelu Academy, and be conducive to the promotion and dissemination of regional root carving culture and academy culture.
Research on the Elements of Tourist Experience Demands in Archaeological Site Parks Based on Grounded Theory
Authors: Chen Yizi , Deng Zihan
Published: February 2024

This study refines the tourists’ five main demand categories of “perceptual presentation demand”, “behavioral interaction demand”, “scene narrative demand”, “content perception demand” and “main goal demand” in the archaeological site parks, through choosing the tourist experience of archaeological site parks as the research object, taking their review texts in the Internet as the basic data, and using the basic research procedures of open coding, spindle coding, selective coding of grounded theory, then verifying the results by the reliability test and the matrix method in social network analysis. The elements of visitor experience demand in archaeological site parks extracted from this study have good credibility to support for the design of visitor experience in archaeological site parks and experience optimization of subsequent related products.
Relationship between vitamin D receptor genotypes (FOK1rs2228570) and IL18 gene expression in sample of multiple sclerosis Iraqi patients
Authors: Lafi* and Zahraa Kadhim , Mohammed Bushra Jasim
Published: February 2024

BACKGROUND: Multiple Sclerosis known as MS, this chronic inflammatory demyelinating condition affects the nervous system. It is a heterogenic and multifactorial disease. The goal of the current study was to investigate the relationship between MS patients’ IL18 gene expression and the vitamin D receptor gene polymorphism (FOK1rs2228570). OBJECTIVE: The aim of the study to investigate the association of vitamin D receptor (FOK1rs2228570) gene polymorphism and pro inflammatory cytokine (IL18) gene expression among multiple sclerosis Iraqi patients. Detection VDR polymorphism and determine whether this SNP is involved in susceptibility to multiple sclerosis and estimation IL18 gene expression and explore its relation with multiple sclerosis susceptibility. METHODS: Blood samples were taken from 75 MS patients in Iraq (30 men and 45 women), as well as from 75 volunteers who seemed to be in a favorable state of health and fell within the age range of 20 to 50 years. Tetra-ARMS Polymerase Chain Reaction (Tetra-ARMS PCR) was used to find polymorphisms in the vitamin D receptor (VDR) gene, and Real-time Polymerase Chain Reaction (RT-PCR) was used to measure IL18 gene expression. RESULTS: The findings from the analysis of VDR gene polymorphism in patients with MS indicated that the wild-type genotype T/T was present in 8 individuals, accounting for 10.6%, the heterogeneous genotype TC was 36 (48%), and the homogeneous genotype CC was 31 (41.3%), whilst T allele frequency was 52(34.6%) and C allele was 98(65.3%) with (P⩽ 0.01) significant difference and even as in control T/T genotype was 49(65.3%), TC genotype was 21(28%), CC genotype was 5(6.66%), T allele frequency was 119(79.3%) and C allele was 31(20.6%) with significant difference (P⩽ 0.001). While estimation of IL18 expression showed high elevation in patients’ group (2.59 ± 0.51 fold) by significance difference (P⩽ 0.5) when compared to control group (1.35 ± 0.14 fold). The relationship between IL18 gene expression with VDR variant in MS patients demonstrated a significant rise (2.9 ± 0.51 fold) at CC genotype patients in IL18 folding gene expression, followed by (4.6 ± 0.17 fold) in TC genotype patients and finally (1.4 ± 0.08 fold) in TT genotype patients with highly significant (P⩽ 0.01). CONCLUSION: The VDR(FOK1rs2228570) genotype was significantly correlated with IL18 expression in MS patients from Iraq.
Effect of physical exercise on inactivated COVID-19 vaccine antibody response in the elderly
Authors: Şevgin Ömer , Özer Songül
Published: February 2024

BACKGROUND: Physical exercise has been proposed as a new alternative to chemical adjuvants. OBJECTIVE: To investigate the relationship between regular exercise and post-vaccination antibody response in the elderly. METHODS: The study was conducted with the elderly over the age of 65. 30 participants we randomized into 2 groups and divided into exercise and control groups. The experimental group received a 12-week exercise program. The control group was followed up without any exercise. The day on which the second dose of the vaccine was administered to all participants was considered day 0. The antibody level in the serum samples was taken 15 days and 12 weeks after the vaccination. The antibody concentration was measured after the second dose of vaccination. RESULTS: The mean antibody level in the control group was 69.4 U/ml and 56.4 U/ml 15 days and 12 weeks after the second vaccination. The mean antibody level in the exercise group was 74 U/ml and 71.6 U/ml 15 days and 12 weeks after the second vaccination. CONCLUSIONS: Regular exercise of light to moderate intensity may increase post-vaccination antibody response in the elderly. Therefore, exercise can be used as a behavioral adjuvant to improve the vaccine efficacy in the elderly.