bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship between oscillations in the basal ganglia and synchronization of cortical activity
Authors: Cassim François , Labyt Etienne , Devos David , Defebvre Luc , Destée Alain , Derambure Philippe
Published: March 2024

The functions of oscillations within the basal ganglia are poorly understood. We discuss in the present paper, the possible physiological or pathological roles of oscillatory activities within the basal ganglia, and their relationship to cortical oscillations. Three aspects are presented: 1. What do we know from animal studies? 2. What do we know from neurophysiological studies in parkinsonian patients? 3. What is the effect of L‐dopa treatment and electrical stimulation within basal ganglia circuits on cortical oscillations?

Animal studies suggest that neuronal oscillations are spontaneously generated within the basal ganglia system, especially from the GPE and the subthalamic nucleus (STN), but are mainly synchronized by cortical activity via the striatal inputs. Dopamine depletion results in a global increase of oscillations within the whole basal ganglia system, particularly in the GP‐NST network. Oscillations within the basal ganglia may, in part, be related to tremor since they are enhanced, especially in the globus pallidus internus (GPI) and the STN, in human and animal dopaminergic depletion. However, they also play a role in the physiology of movement as revealed by coherence analysis between cortex, muscles and GPI/STN in parkinsonian patients undergoing deep brain stimulation. It is known that the basal ganglia may influence cortico‐muscular oscillations such as the Piper rhythm and other rhythms in the beta band. In off‐drug parkinsonian patients, low frequency oscillations (4‐10 Hz) are favoured, presumably resulting in bradykinesia and low force. When medically (L‐dopa) or surgically (deep brain stimulation) treated, these low frequency oscillations are replaced by high frequency (70 Hz) oscillations that are important for motor programs to be correctly executed. Studies of cortical reactivity related to planning of voluntary movement in parkinsonian patients provide evidence that it is possible to influence cortical reactivity through the basal ganglia system.
The treatment of patients with hypothalamic hamartomas, epilepsy and behavioural abnormalities: facts and hypotheses
Authors: Palmini André , Paglioli‐Neto Eliseu , Montes Jose , Farmer Jean‐Paul
Published: March 2024

The growing interest in the association between hypothalamic hamartomas (HH), epilepsy and behavioural abnormalities witnessed in recent years, has led to significant progress regarding the clinical presentations, pathophysiology and management of this entity. Patients with these lesions may occupy different points within a spectrum of severity of the epileptic and behavioural disorder, and may dynamically progress toward more malignant epilepsies with time. The role of the subcortical lesion in the generation of the gelastic seizures has been established, and encouraging results have been obtained with surgical resection, destruction or disconnection of the hamartoma. The present work highlights several aspects that should be taken into account for the selection of medical and surgical treatment for individual patients. We conclude with a reflection on what we still do not understand as regards in the genesis and surgical management of the neuropsychiatric disabilities related to this disorder.
Preliminary efficacy of levetiracetam in children
Authors: Glauser Tracy A. , Dulac Olivier
Published: March 2024

Treatment of seizures in pediatric patients is complicated by the fact that the etiology of the disorder and the pharmacokinetics, efficacy, and safety of antiepileptic drugs (AEDs) may differ from that in adults. With few controlled clinical trials of AEDs in children, the selection of agents to treat pediatric patients must be made on the basis of information from small uncontrolled studies or the extrapolation of clinical trial results in adults. Data from a large number of children with a wide range of seizure disorders who were treated in small‐scale prospective studies, or whose records were retrospectively evaluated, indicate that levetiracetam reduces the frequency of seizures in pediatric patients. Available data also indicate that levetiracetam is well tolerated in pediatric patients, with a safety profile similar to that in adults, a low potential for behavioral disturbances, and no reported idiosyncratic adverse reactions. As with other AEDs, children metabolize and clear levetiracetam more rapidly than adults, and somewhat higher doses (based on body weight) are needed to achieve desired plasma concentrations. Several ongoing studies will provide further information on the pharmacokinetics, efficacy, and safety of levetiracetam in this patient population.
Neuroimaging of focal cortical dysplasia: neuropathological correlations
Authors: Colombo Nadia , Citterio Alberto , Galli Carlo , Tassi Laura , Russo Giorgio Lo , Scialfa G. , Spreafico Roberto
Published: March 2024

Focal cortical dysplasia is a well‐known cause of intractable epilepsy with early onset of seizures, and is potentially amenable to surgical therapy.

It was first described by Taylor in 1971 as a peculiar malformative disorganisation of the neocortex characterised at histology by loss of cortical lamination and accompanied by giant, dysmorphic neurones and, most frequently, by ‘balloon cells’ littered throughout the cortex and sub‐cortical white matter. While in the past decades the term ‘cortical dysplasia’ has referred to various malformations of cortical development, such as agyria, pachygyria, polymicrogyria, heterotopia and hemimegalencephaly, it is now widely accepted that the entity identified by Taylor should be considered separately, from both histological and neuroimaging standpoints. More recently, the recognition of various histological subtypes of focal cortical dysplasia characterised by different degrees of cortical disruption with or without cytological abnormalities has generated several classifications that are still unsatisfactory. With better magnetic resonance capability, subtle and very small focal cortical dysplasias may now be visualised and the differential magnetic resonance aspects of the histological subgroups can be established. We will discuss the problem of histopathological classification and magnetic resonance imaging differentiation of the various subtypes of focal cortical dysplasia in the light of personal data collected from a large series of epileptic patients who underwent surgery and had a histological diagnosis of focal cortical dysplasia.
Factors underlying scalp‐EEG interictal epileptiform discharges in intractable frontal lobe epilepsy
Authors: Vadlamudi Lata , So Elson L. , Worrell Gregory A. , Mosewich Russell K. , Cascino Gregory D. , Meyer Fredric B. , Lesnick Timothy G.
Published: March 2024

Aims

Scalp‐EEG interictal epileptiform discharges (IEDs) may be less predictive of the outcome of frontal lobe epilepsy surgery than of temporal lobe epilepsy surgery. We identified factors associated with the location of scalp‐EEG IEDs in intractable frontal lobe epilepsy.

Methods

Ten factors were assessed in a retrospective review of 53 patients with either concordant (frontal lobe seizure focus) or discordant (generalized or outside frontal seizure focus) IED or both, who had excellent surgical outcomes. The Fisher exact test and the Wilcoxon rank sum test determined statistically significant associations.

Results

Thirty‐six patients (68%) had concordant IED, 24 (45%) discordant IED, and 17 (32%) both. Younger age at onset was significantly associated with discordant IED (mean, 7.5 years
versus
17 years for patients without discordant IED;
P
< 0.01), whereas duration of epilepsy was not. Seizure foci at the frontal convexity were associated with concordant IED. About 72% of patients with a convexity seizure focus had concordant IED, compared with only 33% of patients with mesial frontal foci having concordant IED (
P
= 0.06).

Conclusions

Early seizure onset in intractable frontal lobe epilepsy is associated with IEDs discordant with seizure focus. Frontal convexity seizure foci are more likely than mesial frontal seizure foci to be associated with concordant discharges.
Late onset hyperekplexia
Authors: Hamelin Sophie , Rohr Pascale , Kahane Philippe , Minotti Lorella , Vercueil Laurent
Published: March 2024

We report on the case of an 86‐year‐old woman who rapidly became unable to stand and walk because of jerky movements, suggesting a clinical diagnosis of myoclonus. It was observed that both unexpected and expected stimuli (audiogenic, tactile, or visual) triggered the myoclonic jerks. Electrophysiological exploration, including a coupled EEG‐EMG study, showed the occurrence of a patterned motor response to each stimulation (whatever the modality), consisting of eye blinking, head flexion, abduction of the upper arms, movement of the trunk, and bending of the knees. Given the absence of any relevant past history and lack of biological or neurological abnormalities including on CT scan brain imaging, the diagnosis of late‐onset hyperekplexia was suggested. Substantial abatement of the clinical symptomatology was obtained after introduction of low‐dose clonazepam. [published with videosequences]
Frontal lobe epilepsy
Authors: Kellinghaus Christoph , Lüders Hans O.
Published: March 2024

Frontal lobe epilepsy accounts for only 10‐20% of the patients in surgical series, but the incidence in non‐surgical patient cohorts seems to be much higher. The typical clinical presentation of the seizures includes contralateral clonic movements, uni‐ or bilateral tonic motor activity as well as complex automatism. The yield of surface EEG may be limited due to the difficulty in detection of mesial or basal foci, and the patient may be misdiagnosed as having non‐epileptic events. In addition, in patients with mesial frontal foci the epileptiform discharges may be mislateralized (“paradoxical lateralization”). Therefore, epilepsy surgery has been commonly considered as less promising in patients with frontal lobe epilepsy. However, the advent of sophisticated neuroimaging techniques, particularly MRI with epilepsy‐specific sequences, has made it possible to delineate the epileptogenic lesion and detect a specific etiology, in an increasing number of patients. Thus, the success rate of epilepsy surgery in frontal lobe epilepsy is currently comparable to temporal lobe epilepsy, if the candidates are carefully selected. Patients with frontal lobe epilepsy who do not respond to anticonvulsive medication, and who are not eligible for epilepsy surgery may benefit from alternative approaches such as electrical brain stimulation.
Psychometric validation of the French version of the quality of life in epilepsy inventory (QOLIE‐31): Comparison with a generic health‐related quality of life questionnaire
Authors: Picot Marie‐Christine , Crespel Arielle , Daurès Jean‐Pierre , Baldy‐Moulinier Michel , Hasnaoui Abdelkader EL
Published: March 2024

A psychometric evaluation of a French transcultural version of the quality of life in epilepsy inventory‐31 (QOLIE‐31) was carried out. QOLIE‐31 was compared to a generic health‐related quality of life questionnaire, the Nottingham health profile (NHP). The psychometric properties of QOLIE‐31, assessed in 190 adults with epilepsy, included: acceptability, test‐retest reliability and validity (multi‐trait analysis including internal consistency and item‐to‐scale correlations, construct validity using factor analysis, discriminative validity using relationship with disease characteristics, treatment effects, divergent and convergent validity using correlations with NHP scores). Both acceptability and reproducibility were good and internal consistency was high (Cronbach's a coefficient = 0.86). Factor analysis with varimax rotation identified seven factors with eigenvalues > 1, with two factors, related to cognitive function and mood, accounting for 46.5% of the variance. However, goodness of fit indices revealed that a model with four factors best fitted the data. The first factor corresponds to a generic mental dimension, the second is equivalent to the cognitive functioning dimension, the third to medication effects including social functioning, and the fourth to seizure worry. Discriminative validity was good for seizure control and treatment tolerability. Hight correlations between QOLIE‐31 and pertinent NHP scales (emotional reactions, energy and social isolation) were observed. The French version of QOLIE‐31 thus meets established psychometric criteria for reliability and validity.
Canaux ioniques et épilepsies
Authors: Mazzuca Michel , Lesage Florian , Lazdunski Michel
Published: March 2024

Les canaux ioniques sont à l'origine de la génération et de la modulation de l'excitabilité neuronale. Les crises épileptiques sont la manifestation d'une activité électrique anormale liée à un défaut dans le contrôle de cette excitabilité. Au cours des dix dernières, des mutations génétiques dans une douzaine de canaux ioniques, récepteurs canaux et transporteur ionique ont été associées à différentes formes d'épilepsies idiopathiques. Cet article passe en revue les différents syndromes épileptiques héréditaires impliqués, les mutations associées et leurs effets fonctionnels sur les canaux. Bien que les corrélations entre phénotypes et génotypes soient encore difficiles à établir, les résultats obtenus suggèrent de nouvelles pistes pour le développement de traitements antiépileptiques plus ciblés.
Épilepsies et retard mental : les syndromes génétiques
Authors: Livet Marie‐Odile , Villeneuve Nathalie , Daquin Géraldine , Cournelle Marie‐Anne , Mancini Joselle , Moncla Anne
Published: March 2024

La recherche de l'étiologie d'une déficience mentale chez les enfants et les adultes est fondamentale et nécessite une approche clinique rigoureuse ainsi qu'une collaboration étroite entre les différents spécialistes. Certains syndromes génétiques avec une déficience intellectuelle peuvent être associés avec des dysmorphies, des comportements particuliers, ainsi que des syndromes épileptiques cliniquement repérables. L'identification de ces syndromes épileptiques spécifiques peut être un indice important, conduisant au diagnostic de ces syndromes génétiques. Par ailleurs, ces régions chromosomiques dont les aberrations sont associées de façon significative avec des crises peuvent être des cibles privilégiées pour la recherche des gènes impliqués dans l'épilepsie. Les principaux syndromes génétiques comportant une épilepsie caractéristique sont brièvement décrits : syndrome d'Angelman, duplication de la région 15q11‐q13, syndrome de Wolf‐Hirschorn, syndrome du chromosome 20 en anneau, syndrome de l'X fragile.
Epilepsie et maladies neurodégénératives de l'adulte
Authors: Vercueil Laurent
Published: March 2024

La pathologie neurodégénérative va devenir potentiellement dans les années à venir la première cause d'épilepsie du sujet adulte, en raison du vieillissement de la population occidentale. Curieusement, elle reste, comme cause d'épilepsie, très peu étudiée, tant dans ses aspects épidémiologiques, diagnostiques que thérapeutiques. Dans la maladie d'Alzheimer, environ 10 % de sujet présentent une épilepsie, nécessitant souvent le recours aux traitements antiépileptiques. Ce travail présente une revue de la littérature consacrée à ce sujet, et discute des principes thérapeutiques dans ce contexte.
Mortality in adult patients with epilepsy in Taiwan
Authors: Chen Rong‐Chi , Chang Yang‐Chyuan , Chen Tony Hsiu‐Hsi , Wu Hui‐Min , Liou Horng‐Huei
Published: March 2024

To investigate mortality in adult patients with epilepsy in Taiwan, a total of 263 patients with epilepsy aged ≥ 17 years, referred to the outpatient epilepsy clinic between 1 Jan and 31 December 1991, were prospectively enrolled and followed up until 31 December 2000. A total of 32 deaths were reported. Overall case‐fatality rate was 12.2%. The age‐adjusted standard mortality ratio (SMR) was calculated to compare the risk of death in patients with epilepsy to the general population. Patients with epilepsy had a 3.5‐fold higher risk of death as compared with the general population (SMR: 3.47, 95% CI: 2.46‐4.91). The Cox proportional hazards regression model was used to assess relevant clinical contributions to death. Patients with an age‐at‐onset ≥ 40 years had a 4‐fold higher risk of death as compared with those with an earlier onset. The multivariate analysis revealed that age‐at‐onset between 40 and 59 years, tumor etiology, and being male increased the risk of death in epilepsy. One‐third of the deaths in patients with age‐at‐onset between 40‐59 years died of liver cirrhosis and hepatoma. Hepatitis B virus infection is endemic in Taiwan, and this is closely associated with liver cirrhosis and hepatoma. Whether anticonvulsants contributed to the hepatotoxicity that led to fatal liver disease in this group needs further investigation.
Atypical absences and recurrent absence status in an adult with Angelman syndrome due to the UBE3A mutation
Authors: Espay Alberto J. , Andrade Danielle M. , Wennberg Richard A. , Lang Anthony E.
Published: March 2024

Angelman syndrome is a neurogenetic disorder resulting in refractory epilepsy and profound psychomotor retardation in its most prevalent form, caused by deletion of maternal chromosome 15q11‐13. We report the case of a 29‐year‐old, mentally retarded man with unusual electroencephalographic changes during periods of atypical absence status epilepticus, a previously unreported manifestation of the usually milder, drug‐responsive epilepsy associated with Angelman syndrome due to the UBE3A mutation.
[Published with video sequences]
Can we predict refractory epilepsy at the time of diagnosis?
Authors: Semah Franck , Ryvlin Philippe
Published: March 2024

The early prediction of intractability is a major challenge in epileptology. Some prognostic factors have been pointed out, most of which simply underlined that partial epilepsy is more difficult to control than idiopathic generalized epilepsy (IGE). Indeed, the main predictors are the presence of a brain lesion demonstrated by neuroimaging or suggested by a neurological deficit or a developmental delay, as well as electroclinical evidence of non idiopathic partial epilepsy. Little is known about the relationship between the location of the epileptogenic area and the chance of being seizure‐free in patients with partial epilepsy. Some data suggest that temporal lobe epilepsy (TLE) is more difficult to control than other partial epilepsies, but this might only reflect the prognostic impact of hippocampal sclerosis. Indeed, several studies have shown that the majority of patients with MRI evidence of hippocampal sclerosis develop refractory epilepsy. This observation also applies to patients with malformation of cortical development (MCD). The response to the first AED is another early predictor of refractory epilepsy. At the time of diagnosis, several prognostic factors are available to predict drug resistance, but further studies are still needed to better delineate the specific role of each of these factors, and to offer a more accurate prediction of long term seizure outcome.
The consequences of idiopathic partial epilepsies in relation to neuropsychological functioning: a closer look at the associated mathematical disability
Authors: Sart Z. Hande , Demirbilek Veysi , Korkmaz Barış , Slade Peter D. , Dervent Ayşın , Townes Brenda D.
Published: March 2024

Although the seizure prognosis is mostly favorable in idiopathic partial epilepsies, there is some empirical evidence showing that subtle neuropsychological impairments, with a consequent risk of academic underachievement, are not rare. We investigated neuropsychological functioning including attention, memory, visuomotor ability, and executive functioning with a closer look at the associated mathematical ability in patients with idiopathic partial epilepsies. A battery of age‐appropriate, neuropsychological and mathematics achievement tests was administered to 30 participants with idiopathic partial epilepsy [13 children with benign epilepsy with centrotemporal spikes (BECTS), 17 children with idiopathic childhood occipital epilepsies (ICOE)], and to 30 healthy participants matched for age, sex, handedness, and socioeconomic status. Results did not support any impairment in overall neuropsychological functioning in participants with idiopathic partial epilepsies, whereas, isolated deficits did exist. The mean performance of the IPE group was significantly lower than the control group in six out of 12, neuropsychological measures: drawing (p < 0.01), digit span (p < 0.05), verbal learning (p < 0.01), object assembly (p < 0.01), similarities (p < 0.05), and vocabulary (p < 0.001). Results suggested that one should be cautious regarding neuropsychological and academic prognosis in the so‐called benign idiopathic partial epilepsies of childhood.
Seizures, epilepsy and vascular disorders
Authors: Rumbach Lucien
Published: March 2024

Stroke is a major cause of seizures in the elderly. About 10% of all stroke patients experience one or several seizures; they may occur during the first 24 hours after the stroke, in the early and late stages and after several months or even years following the initial vascular accident. We review current data on epidemiology, risk factors, semiology, differential diagnosis, follow‐up and recurrence, and management of seizures following stroke.
Совершенствование модели управления качеством электроэнергии в системах электроснабжения потребителей сетевой организации с нелинейными нагрузками
Authors: Чикин Владислав Владимирович , Кузнецов Анатолий Викторович
Published: March 2024

Предложены новые подходы к совершенствованию модели управления качеством электроэнергии в системах электроснабжения потребителей сетевой организации с нелинейными нагрузками. Для достижения цели исследования применены теоретические методы научного исследования, такие как анализ, синтез, абстрагирование и математическое моделирование. Совершенствование модели управления качеством электроэнергии предполагает изменение состава участников правоотношений, новый способ оценки стоимости вредных последствий и новый оплачиваемый технический параметр для определения значений управляющих факторов. Предложена методика расчета и использования надбавок (скидок) к оплате потребляемой электроэнергии за генерацию и потребление токов гармонических составляющих. Оценочный расчет надбавок (скидок) на примере потребителей сетевой организации показал адекватность предложенной методики. На настоящем этапе развития модель управления качеством электроэнергии в системах электроснабжения потребителей сетевой организации с нелинейными нагрузками нуждается в совершенствовании. Для решения задачи повышения ее эффективности требуется системный подход с привлечением специалистов из различных областей знаний.
Очистка немагнитных многокомпонентных сред, перемещаемых на конвейерах методом прямой сепарации
Authors: Парсентьев Олег Сергеевич
Published: March 2024

Рассмотрена проблема разработки энергосберегающего технологического подхода – системы дискретного обнаружения и извлечения металлочастиц, вероятность появления которых на входе в подсистему сепарации описывается законом редких событий (Пуассона). Предложены методы и приборы обнаружения металлочастиц, позволяющие сделать процесс извлечения дискретным, т.е. при наличии металлофрагментов. Для решения поставленных задач использован системный подход, включая математическое моделирование процессов с использованием метода интегральных уравнений. По результатам анализа статических и динамических характеристик двухблочного комбинированного железоотделителя (КЖ) установлено, что в интервале времени действия импульса намагничивающих сил в обмотках, извлекающие силы превышают конкурирующие силы при встречном направлении тока в обмотках в 7,2 – 13,2 раза. Реализация предложенного энергосберегающего подхода в транспортной системе позволила снизить расход электроэнергии, в зависимости от изменения скорости движения (1,6 – 2,5 м/с) ленты конвейера, в 4,8 – 8,3 раза, повысить производительность очистки в 1,25 раза и ее эффективность в 1,2 – 2,7 раза. Предлагаемая конструкция двухблочного КЖ в сравнении с подвесными железоотделителями, выпускаемыми отечественной промышленностью, отличается высокой энергоэффективностью, быстродействием, имеет малые габариты, вес, низкую металлоемкость и потребление электрической энергии.
Evaluation of soil fertility index in organic, semi-organic, and conventional rice field management systems
Authors: Suntoro Suntoro , Herdiansyah Ganjar , Widijanto Heri , Minardi Slamet , Dewi Febridita Sari
Published: March 2024

Rice farming in Madiun Regency implements three different management systems, that is organic, semi-organic, and conventional. The different implementation of these rice field management systems impacts soil fertility index and rice productivity. This purpose of this research was to know the effect of rice field management systems on soil fertility index and rice productivity in the Madiun Regency. The research uses an explorative descriptive qualitative method with a survey approach. Soil samples were taken using a random sampling method and 3 types of soil management systems (conventional, semi-organic and organic), and rice production samples were taken using an estimation method. The research results show that the soil fertility index ranges from 0.78 to 0.82, which is high. The highest soil fertility index is in the semi-organic management system and the lowest is in the organic management. The management system of semi-organic gave a response to the highest rice production of 6.89 tons/ha. Management system of semi-organic is a better management for increasing and maintaining soil fertility and crop production than conventional or organic. Farming activities results show that organic management systems increase the highest income, increasing 115.58% and 53.30% in semi-organic compared to conventional. The rice field management system has the effect of increasing the worm population density with the highest in the organic system, namely 4.19 individuals m-2. The Pontoscolex worm type dominates the three management systems. There is a correlation between organic matter content and earthworms.
İSTATİSTİKSEL SÜREÇ KONTROLÜ İLE İLETKEN ENDÜSTRİSİNDE KALİTE İYİLEŞTİRME UYGULAMASI
Authors: Meran İrem , Güner Gören Hacer
Published: March 2024

Süreci kontrol altında tutarak yüksek kalitede ürün elde etmek, hurda oranını azaltmak ve müşteri memnuniyetini sağlamak kalite araçları kullanarak mümkündür. Bunlardan en yaygın kullanılanı bir süreci kontrol altında tutmak, izlemek ve iyileştirmek amacını taşıyan İstatistiksel süreç kontrolüdür (IPK). Bu çalışmada iletken endüstrisinde faaliyet gösteren bir firma için istatistik süreç kontrol teknikleri ile kalite iyileştirme çalışmaları yapılmıştır. Öncelikle, temel istatistiksel süreç kontrol tekniklerinden histogram, pareto analizi, serpilme diyagramları ve kontrol çizelgeleri kullanılarak bir ürün için sürecin mevcut durum analizi yapılmıştır. Beyin fırtınası ve balık kılçığı diyagramı yardımıyla sürecin yeterliliğinin düşmesine sebep olduğu düşünülen kök nedenler belirlenmiştir. Daha sonra, çok değişkenli regresyon analizi ile süreçte etkili olduğu düşünülen girdiler analiz edilmiştir. Regresyon analizinin sonucuna göre deney tasarımları geliştirilmiş ve tekrar ilişki denklemi kurulmuştur. Hedef süreç yeterliliğine ulaşabilmek için tasarlanmış deneylerden elde edilen parametreler ile üretim yapılmış ve elde edilen sonuçlara göre sürecin müşteri isteği doğrultusunda iyileştirildiği gözlenmiştir. Bu çalışma, istatistiksel süreç kontrol tekniklerinin endüstriyel uygulamalarda kullanımının iş gücü, zaman, kaynak kullanım verimliliği ve müşteri memnuniyeti sağlayabileceğini göstermiştir.
ABC, TLBO, TLABC ve FDB-TLABC ALGORİTMALARININ BETONARME SÜREKLİ KİRİŞLERİN OPTİMİZASYONU ÜZERİNDEKİ BAŞARIMI
Authors: Öztürk Hasan Tahsin , Temiz Sebahat
Published: March 2024

Bu çalışmada ilk olarak, betonarme sürekli kirişlerin detaylı tasarımlarının minimum maliyetle yapılabileceği bir süreç tasarlanmıştır. Ardından bu problem üzerinde FDB-TLABC, TLABC, TLBO ve ABC algoritmalarının performansları değerlendirilmiştir. Bu amaçlarla öncelikle Türk betonarme standardı ve deprem yönetmeliği dikkate alınarak optimizasyon problemi oluşturulmuştur. Bir, iki ve üç açıklıklı kiriş örneklerinden oluşan bir problem takımı hazırlanmıştır. Bu problem takımı üzerinde yapılan testlerden algoritmaların optimum sonuca ulaşma performansları ile belirlenen makul çözümlere ulaşma süreleri ve başarıları belirlenmiştir. Optimum sonuca ulaşmada, TLABC ve FDB-TLABC algoritmalarının en başarılı algoritmalar olduğu görülmüştür. Kararlılık analizinden, TLABC algoritmasının en yüksek kararlılığa ve hıza sahip olduğu görülmüştür.
PI CONTROLLER DESIGN FOR TIME DELAY SYSTEMS USING DIFFERENT MODEL ORDER REDUCTION METHODS
Authors: İrgan Hilal , Tan Nusret
Published: March 2024

This study focuses on designing PI controllers for time-delay systems using various model order reduction techniques to reduce complexity. The stability boundary locus method was used to determine PI parameters that stabilizing reduced order models. After the PI parameters have been determined using the weighted geometric center method, the calculated controller parameters have been implemented in the original system. In this way, the efficiency of the controller design is effectively demonstrated through the reduction techniques. In addition, the study investigated the effectiveness of reduction methods with increasing time delay and adding an integrator to the system. The importance of these results is that they demonstrate the use of model order reduction techniques in the design of controllers for time-delay systems and reveal the advantages of these methods.
CMT-93 Cell Culture Protocol v1
Authors: Gómez Laura
Published: March 2024

CMT-93 is a cell line exhibiting epithelial morphology that was isolated from the rectum of a mouse with polyploid carcinoma.
Streaking bacteria on a Petri Plate from -70C frozen culture v1
Authors: Tollafield Emma , Dutta Dibyendu , Moebius Wolfram
Published: March 2024

This protocol describes how to obtain isolated single colonies of any bacterial strain by streak plating, from a -70C frozen stock culture.
Tata Kelola Pembinaan di Lentera Tari Prodi Pendidikan Seni Pertunjukan FKIP Universitas Lambung Mangkurat
Authors: Permata Kumala Sari Putri Yunita , Hartono H , Syakir S
Published: March 2024

'Lentera Tari' is one of the UKM (Student Activity Units) which is part of the 'Lentera Seni Performing' and is under the management of the Student Association (Hima) of Performing Arts Education FKIP, Lambung Mangkurat University. UKM which is owned by the Performing Arts Education Study Program FKIP ULM was formed as an effort to develop the potential of student specialization. The research method used is qualitative to capture existing phenomena and describe them concretely. This SME development system uses a governance approach from George R. Terry, who suggests the basic function of governance as a dynamic process which includes planning, organizing, actuating, monitoring or evaluation functions. In the management of 'Lentera Tari', the results obtained include: 1) the planning process in the weekly, semi-annual and incidental coaching agenda; 2) in organizing in the form of division of jobdesk fields and responsibilities of each; 3) in the process of movement in the form of the travel process of all members of the 'Lentera Tari' in coaching activities, coordination of performances and all work programs that have been planned and determined together; 4) at the monitoring stage is through evaluation for the members of the 'Lentera Tari' after each routine training material is finished, both knowledge of the text and context, with the aim of knowing the absorption of coaching, then evaluating to discuss the obstacles encountered during the coaching process, in order to strive for activities in accordance with predetermined plan.
Efektivitas Pelaksanaan Diklat Calon Guru Penggerak Angkatan 4 Berdasarkan Model Evaluasi Kirkpatrick di Balai Besar Guru Penggerak (BBGP)
Authors: Nisa Ikrima Thohorun , Sutarsih Cicih , Sudarsyah Asep
Published: March 2024

This study aims to determine the level of effectiveness of training in the 4th batch of teacher mobilizer program organized by the West Java Teacher Mobilizer Center (BBGP). Measurement of the effectiveness of education and training uses the Kirkpatrick evaluation model, with 4 levels, namely: level 1 (reaction), level 2 (learning), level 3 (behavior), and level 4 (result). The research method used in this study is a descriptive research method with a qualitative approach. Data collection techniques through interviews and documentation studies. Then checking the validity of the data is done by triangulation of techniques and sources. The results showed that the Implementation of Training for Prospective Teacher Movers Batch 4 Based on the Kirkpatrick Evaluation Model at the West Java Center for Teacher Movers (BBGP) at levels 1 and 2 was considered effective but at levels 3 and 4 it was not considered effective.
Analisis Kepuasan Kerja Pegawai Pada Transformasi Balai Besar Guru Penggerak Provinsi Jawa Barat
Authors: Martini Dede Herika , Triatna Cepi , Rosalin Elin
Published: March 2024

This research is entitled "Analysis of Employee Job Satisfaction at the Transformation of the West Java Provincial Teacher Training Center". This study aims to determine employee job satisfaction at the transformation of the West Java Provincial Teacher Training Center, find out the factors that affect employee job satisfaction at the West Java Provincial Teacher Training Center, and formulate strategies to increase employee job satisfaction at the West Java Provincial Teacher Training Center. The method used is a qualitative method with a case study approach. The determination of respondents using snowball sampling technique. The results of this study indicate that employee job satisfaction is felt from the dimensions of the job itself, salary, supervision, coworkers, and working conditions. When referring to the dimensions put forward by Fred Luthans related to the job itself, employees get job satisfaction, but when referring to the main tasks and functions of each employee's job, employees have not received job satisfaction. In addition, from the promotion dimension, employees also have not received job satisfaction. Employee job satisfaction is influenced by internal and external factors. In order to increase job satisfaction, it is necessary to formulate strategies to increase job satisfaction
Limit location in post-classical systems
Authors: Agapitova Anastasia V.
Published: March 2024

The paper comments on the theory of post-non-classical systems from the position of geterology about religious search and finding God or absolute in conditions of post-non-classical view on a social world. At the end of an article is presenting a conclusion about the way of answer on the question by the volitional collective stop of the dynamics of social interactions.
The problem of the political component of post-non-classical science and education
Authors: Maslov Vadim M.
Published: March 2024

The work is devoted to understanding the process of political involvement of modern science and the need for the post-non-classical scientific community to become a subject of political activity. In historical terms, we are talking about the actualization of F. Bacon’s ideas about the beneficial connection of a new science with power. Philosophical education can serve as a basis for the formation of appropriate political competencies among future scientists and engineers.
Ideological design: some aspects of the methodological analysis of mental wars
Authors: Sokolova Marianna E.
Published: March 2024

The article considers a number of theoretical and methodological approaches to designing the image of Russia of the future, among them a living system of mythologems (by N.A. Sergeev and E.G. Nikitenko), an analysis of key civilizational archetypes (M.A. Makarenkov), a theoretical and methodological analysis of the project of a systemic ideological worldview based on the «Concept of the Foreign Policy of the Russian Federation» (E. Makarov). The importance of methodological support on the analysis of the national history of the ideological trends studied in the book «Ideological landmarks in the history of Russian philosophy” by A.D. Sukhov (2023). The importance of the methodological apparatus proposed by the author for modern ideological design is emphasized.
Values of the world-building cultural tradition
Authors: Tyugashev Evgeny A.
Published: March 2024

The article gives an axiological characteristic of the world-building cultural tradition as one of the main traditions that determine the civilizational development of Russia. The main values of this tradition are autocracy, mutual veneration, liveliness, renovation, cunning.
Ideas of the past and their implementation in the modern mentality
Authors: Pendyurina Lyudmila P.
Published: March 2024

The article attempts to consider the concept of the past as a necessary condition for human existence, analyzes the spheres of its implementation in the historical activity of people. One of the aspects of the past is the history of ideas, in which the most important place belongs to the theological ideas of Plato, explicated in the mentality of the 20th and 21st centuries.
The ambivalence of technogenic civilization’s axiological foundations
Authors: Ratnikova Irina M.
Published: March 2024

The paper is devoted to identifying the specifics of civilizational dynamics of modernity through the theoretical reconstruction of Critical Theory, the key subject of which is the fundamental principles of Technogenic civilization. Based on the conceptual resources of the newest version of this research program, the ambivalence of the axiological foundations of Western culture and its foundation on the logic of domination-subordination is revealed on the example of the discourse and practice of tolerance. The heuristic potential of Critical Theory in the context of overcoming pathologies of modern civilization development is explicated in the article.
Experiences of physical education teachers in District of Dinalupihan on students' performance assessment in times of covid-19 pandemic
Authors: Sinag Jay Mark Dela Pena
Published: March 2024

The global COVID-19 pandemic has brought modifications to the world’s education system and not only in the Philippines and requires us to adapt to the change in the teaching-learning process which both teachers and students has to face for the quality education of the country. The radical shift to digital pedagogy followed by online assessments and examinations brought new experiences to both educators and learners like using different technological softwares. This study utilized a qualitative-phenomenological research approach that seeks to understand and describe the universal essence of a phenomenon. The approach investigates the everyday experiences of human beings while suspending the researchers’ preconceived assumptions about the phenomenon (Alchemer, 2021). This study was participated by the Physical Education Teachers from the Department of Education who experienced the new modalities of delivering the subject. The objectives of this study is to identify the problems that physical education teachers face while assessing students' performance, coping methods do physical education teachers use to deal with the challenges, and to look for intervention strategy can be suggested based on the study's findings? Two (2) themes were developed and 8 subthemes were revealed as a result of the data analysis. The themes revealed the most of experiences of the teachers on the assessment of students’ performance and how they respond to the challenges. As a result of these findings, the researchers created an Intervention Program to assist them in developing and improving their knowledge, skills, talents, conduct and teaching competencies to address the issues.
Explicit instruction in fitness exercise for PATHFit II (physical activities towards health and fitness)
Authors: Velez Laarni
Published: March 2024

Explicit instruction is a purposeful way of overtly teaching students. Explicit in this case, means a clear-cut and finite method of teaching that includes both teaching and delivery procedures. Using this learning, the students perform the skills of the different fitness exercises through practical demonstration with clear and specific instruction. The teachers would tell the students using direct instructions to demonstrate the skills, respectively. Thus, this research determined the efficacy of explicit instruction in fitness exercises for pathfit II at Biliran Province State University – Main, Naval, Biliran during the academic year 2021 – 2022, as basis for enhancement activities. The study used a quasi-experimental research design and had one hundred (100) respondents involved in the survey. Findings revealed the skills performance of the students was excellent after using explicit instruction in fitness exercises as to; muscular strength – push up, muscular endurance - planking, flexibility – sit and reach, and cardiovascular endurance – 3-step test. In other words, there was a significant difference between how well students performed their skills before and after using explicit instruction in fitness exercises. In essence, this paper recommends adopting explicit instruction in teaching fitness exercise to enhance students’ skill performance in terms of muscular strength, muscular endurance, flexibility, and cardiovascular endurance to ensure that the students can adhere to the proper method of exercise to successfully complete the tasks.
Effectiveness of learning time for physical education sports and health at Senior High School 10 Malang
Authors: Putra Prawira Adityamawardhana , Winarno Mashuri Eko
Published: March 2024

This study aims to determine the effectiveness of learning hours for physical education, sports, and health at Senior High School 10 Malang by using quantitative and qualitative descriptive methods. Data collection was carried out by researchers through observation and documentation techniques. The results showed that PJOK learning time was not effective at Senior High School 10 Malang, with an average time of 68 minutes as a percentage of the total time of 76%. However, the average pre-activity duration was 7 minutes (8%), the average duration of the core activities was 55 minutes (61%), and the average duration of the final activity was 6 minutes (7%). The conclusion of this study is that the hours of learning sports, physical education, and health at Senior High School 10 Malang are not very effective. The study hours for PJOK subjects at school do not meet the guidelines. According to these guidelines, each learning activity carried out by the teacher consists of 10% preparatory/preparatory activities, 80% core activities, and 10% final/closing activities.
Survey of mastery of basic skills of playing futsal in 15-17 year old futsal athletes
Authors: Prasetyo Mustofa Aji , Supriatna Supriatna , Taufik Taufik
Published: March 2024

This study aims to determine the level of physical condition of Vasco Futsal Academy players in Lamongan Regency. This research is a type of quantitative descriptive research. The subjects of this study were Vasco Futsal Academy players, totaling 20 people. The data collection process was taken using one FIK Jogja battery tes instrumen which included passing, dribbling, and shooting. Overall, the results of the Vasco Futsal Academy's basic futsal tes results showed 10% “very good”, 15% “good”, 40% “moderate” and 30% “poor”, and 5% “very poor”. The conclusion obtained in this study is that the level of mastery of the basic skills of playing futsal by Vasco Futsal Academy players generally shows sufficient results, which is indicated by 40% being in the "enough " category.
Survey of physical conditions of prospective athletes "Perisai Diri" Malang District branch
Authors: Khasanah Wahyu Nadia Nur , Hariyanto Eko
Published: March 2024

Physical conditions greatly affect the ability and skills of an athlete to master movement in a sport, especially Pencak Silat. The purpose of this research is to find out how the physical condition of the athletes at the level of prospective families of the Perisai Diri branch of Malang Regency is. This study used a descriptive quantitative research design and used survey research methods. The results of the survey research on the physical condition of Cakel (Prospective family level) of the Malang Regency branch of Perisai Diri showed that the average physical condition of the red belt level athletes or prospective families of the Malang Regency branch of Perisai Diri was included in the "Medium" category (30%) with an average score of The average is 250.66 and the percentage value of red belt level athletes or prospective families who have "Very Good" physical conditions are 0 athletes (0%), "Good" is 13 athletes (43%), "Medium" are 9 athletes ( 30%), "Less" by 5 athletes (17%) and "Very Less" by 3 athletes (10%). From this study, it can be concluded that the intensity and frequency of an athlete's exercise greatly affect the athlete's physical condition.
Plan de intervención psicoterapéutica para reducir los efectos emocionales del Síndrome del nido vacío en adultos mayores.
Authors: Guadalupe-Tixi Paola , Santos Morocho Jose
Published: March 2024

El síndrome del nido vacío es un trastorno psicológico que conlleva implicaciones emocionales significativas para los progenitores cuando sus hijos dejan el hogar. Entre las experiencias comunes se encuentran la ansiedad, la depresión, la carencia de estrategias de afrontamiento y la disfuncionalidad familiar. Objetivo: El propósito es diseñar un plan de intervención psicoterapéutica destinado a mitigar los efectos emocionales del síndrome del nido vacío en adultos mayores. Material y métodos: Se llevó a cabo un estudio descriptivo-exploratorio con un enfoque cuantitativo, utilizando un diseño pretest. La muestra, constituida por 100 adultos mayores de 65 años, se seleccionó mediante muestreo por conveniencia. Se diseñó un cuestionario que incluía variables demográficas y se aplicaron pruebas como el Mini Mental, Yesavage, Apgar Familiar, Hamilton-Ansiedad y Afrontamiento CAE. Los datos se analizaron con el programa estadístico SPSS V 22.00 y Stata 17.0. Resultados: Se observaron diferencias significativas en indicadores emocionales y otras variables sociodemográficas, particularmente en depresión, disfunción familiar, falta de afrontamiento y ansiedad (p > 0,05). Asimismo, se encontró que la edad, el sexo, la residencia y el estado civil ejercen una influencia significativa (P > 0,05). Conclusión: El plan de intervención psicoterapéutica enfatiza la importancia de mejorar la salud, los estilos de vida y la dinámica familiar, así como fomentar la integración de las personas mayores en la sociedad.