bluuebunny/crossref_metadata_2025 huggingface dataset:
Development priorities of Ukrainian-Polish cross-border tourism market in conditions of intensification of European integration processes
Authors: Bilanyuk Olha
Published: March 2020

The development of cross-border tourism markets can not be considered beyond the basic principles of EU development policy - smart, sustainable and inclusive growth. The approach to the development of tourism based solely on the use of cultural and natural resources is unpredictable in modern conditions. European experience proves that it is important to consider tourism not as a sphere in the shadow of the industrial sector, but as an integral part of the regional innovation system and an element of the development of the knowledge economy in the region. At the same time, smart-development of tourism is based not only on the active use of the newest information and communication technologies, but also on managerial innovations, production of innovative types of tourist services, application of technologies related to the use of robotics, innovative medical equipment, renewable energy, etc. The purpose of the article is to determine strategic priorities of the development of cross-border tourism market on the basis of smart-specialization, definition of directions of joint actions of Ukraine and the EU countries (both at the level of authorities and local self-government, and business sector) in the development and promotion of new tourist products, substantiation of directions of effective the use of endogenous tourist potential of a cross-border region in conditions of activation of European integration processes. On the basis of the study, main development directions of Ukrainian-Polish cross-border tourism market on the basis of smart-specialization are defined as following: creation of a digital platform for the Ukrainian-Polish cross-border tourism market, active promotional campaign for tourist products of Ukrainian-Polish cross-border tourism market, development of cycling tourism and creation of an inter-state bicycle route, expansion of market by increasing the number of tourists aged 55+ and creation of tourist products for this age group as well as development of sentimental (nostalgic) tourism.
PENERAPAN MODEL PEMBELAJARAN PICTURE AND PICTURE PADA MATERI PRINSIP KERJA SISTEM PENGAPIAN ELEKTRONIK
Authors: Elisnawati  , Debora  , Jhonni Rentas Duling
Published: March 2020

From the results of observations and interviews with the teacher who taught the material understand the working principle of an electronic ignition system at SMK Negeri 2 Katingan Hilir, it’s known that the value of TBSM class XI students has not been fully achieved. This is related to the learning outcomes of some students who scored below 65, which did not meet the KKM score set by the school. This study aims to find out how student learning outcomes after applying the picture and picture learning model. The collection is done by using test methods in the form of pre-test and post-test, student response questionnaire, observation in the form of teacher activity sheets and student activity sheets, as well as documentation. The application of the picture and picture learning model to the material understanding the working principle of electronic ignition system of the students of Vocational High School 2 Katingan Hilir, which has been able to make students who take this model successfully obtain complete results and exceed the KKM set by the school which is 70 with 85.67 and lowest value 69 and classical completeness 95.83%. There is a significant increase in student learning outcomes
PENGARUH PEMBELAJARAN SCRAMBLE TERHADAP HASIL BELAJAR ELEKTRONIKA KELAS X TKR SMKN 1 PALANGKA RAYA
Authors: Irvan Wahyu Dinata  , Debora  , Jhonni Rentas Duling
Published: March 2020

The purpose of this study was to determine the effect of scramble learning model on automotive basic technology of electronics lesson on learning outcomes of class X TKR student of SMKN 1 Palangka Raya. This type of research uses true experiment design, the form of research design used in this study uses the form of the pretest and posttest control group design type wherein the initial test will be given before treatment is given and the final test will be given before treatment. The results of this study indicate that the calculation using the t test with a significance level of ? = 0.05 obtained a value of 6.24 while the value of 2.005. This means that H0 is rejected and H1 is accepted, so it can be concluded that there is an influence of student learning outcomes taught using the Scramble learning model on the basics of electronics lesson
PENGARUH MODEL PEMBELAJARAN COURSE REVIEW HORAY TERHADAP HASIL BELAJAR PADA MATERI MENGANALISIS BEARING
Authors: Mardani  , Debora  , Wiyogo
Published: March 2020

Course review horay is one type of cooperative learning. This learning is a test of the understanding of students who use boxes that meet the questions and are numbered to answer them. Students who get the right sign at the earliest immediately shout horror or other yells. The purpose of this study was to study the effect of the course horay review model on the learning outcomes. This study was a pre-experimental with one group pretest-posttest design. The sample of this study was the students of Motorcycle Business (TBSM) which 28 students. The results of the parametric hypothesis test using the t test two correlated samples obtained the value of t count > t table (4,44 > 2,01). Because t count = 4.44 is greater than t table = 2.06, this means that H0 is rejected and H1 is accepted, which means that it relates to the learning model influencing the course review horay model on student learning outcomes
PENERAPAN MODEL PEMBELAJARAN OPEN ENDED PROBLEM UNTUK MENINGKATKAN HASIL BELAJAR SISTEM KOPLING GANDA
Authors: Raflyanto  , Wiyogo  , Jhonni Rentas Duling
Published: March 2020

This study aims to determine; (1) teacher activities after applying the open ended problems learning model in class XI TBSM SMKN 1 Kurun, (2) student activities after applying the open ended problems learning model in class XI TBSM SMKN 1 Kurun, (3) student responses after applying the open ended problems learning model on the double clutch system lesson, and (4) learning outcomes of class XI TBSM SMKN 1 Kurun, after following the open ended problems learning model on the double clutch system lesson. This research is descriptive quantitative, this research took the subject of class students XI TBSM SMKN 1 Kurun chosen as the subject of research. The instrument used is a test of cognitive learning outcomes, student activity sheet, teacher activity sheet, and student response questionnaires. As well as student learning outcomes related to cognitive, affective and psychomotor aspects. The results of data analysis showed that overall student activity was carried out well. The completeness of the classically tested cognitive learning outcomes of students in 13 people (92,85%) and 1 student has not yet finished (2,94%), so classically the results of student learning using open ended problems models are said to be successful
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE THINK-PAIR-SHARE (TPS) TERHADAP HASIL BELAJAR SISWA PADA MATERI MENGGUNAKAN ALAT UKUR
Authors: Frans Tinus  , Debora  , Wiyogo
Published: March 2020

This study aims to determine the effect of Think-Pair-Share (TPS) learning model on student learning outcomes in using measuring instruments on pneumatic systems lesson. The research methods used are experimental. The sampling technique is random sampling, where the first sample of class X TBSM with the number of students is 32 people, which is taught by the TPS and the second sample class X TBSM with a total of 26 people taught by conventional models, instruments used is a multiple choice test which amounts to 40 questions before the test questions are used to test the validity, reliability, differentiation, and level of difficulty of the questions. The results showed that H0 is rejected and H1 is accepted, which shows that there are influences of student learning outcomes taught using cooperative learning type TPS with student learning outcomes.
PENGARUH MODEL PEMBELAJARAN PBL TERHADAP HASIL BELAJAR PADA MATERI PRINSIP KERJA MESIN
Authors: Elby  , Duling Jhonni Rentas , Wiyogo
Published: March 2020

Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh penerapan model Problem Based Learning (PBL) terhadap hasil belajar pada materi prinsip kerja mesin siswa kelas X TKRO, SMKN 1 Kurun, Tahun Akademik 2018/2019. Metode penelitian ini adalah true experimental design (posttest-only). Teknik pengambilan sampel dilakukan secara random sampling, yaitu kelas X TKRO dengan jumlah 30 siswa diajar dengan menggunakan model pembelajaran PBL, sedangkan kelas X TSM dengan jumlah 34 siswa diajar dengan model konvensional. Instrumen yang digunakan adalah tes pilihan ganda berjumlah 50 pertanyaan. Sebelum instrumen tes digunakan, terlebih dahulu diuji validitas dan reliabilitas. Hasil penelitian menunjukkan bahwa ada pengaruh hasil belajar siswa yang diajarkan dengan menggunakan model PBL dengan siswa yang diajarkan model konvensional.

 

Abstract: This study aims to determine the effect of the application of the Problem Based Learning (PBL) model to learning outcomes on the subject matter of machine work class X TKRO, SMKN 1 Kurun, Academic Year 2018/2019. This research method was true experimental design (posttest-only). The sampling technique was carried out by random sampling, namely class X TKRO with a total of 30 students being taught using the PBL learning model, while class X TSM with a total of 34 students being taught with the conventional model. The instrument used was a multiple choice test totaling 50 questions. Before the test instruments are used, validity and reliability are tested first. The results showed that there was an influence on student learning outcomes taught by using the PBL model with students being taught the conventional model.
PENGARUH MODEL PEMBELAJARAN INKUIRI TERHADAP HASIL BELAJAR PADA MATERI BUBUT DASAR SISWA KELAS X TPM SMK NEGERI 1 PALANGKA RAYA
Authors: Junaidi Ledi , Duling Jhonni Rentas , Wiyogo
Published: March 2020

Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran inkuiri terhadap hasil belajar siswa pada materi bubut dasar. Metode penelitian ini adalah pra-eksperimen pretest-postest. Teknik pengambilan sampel menggunakan purposive sample. Sampel dalam penelitian ini adalah 28 siswa yaitu siswa kelas X TPM. Instrumen yang digunakan adalah tes pilihan ganda yang berjumlah 40 pertanyaan. Sebelum soal tes digunakan, intrumen diuji validitas, reliabilitas, daya pembeda soal, dan tingkat kesulitan soal. Berdasarkan hasil analisis data yang telah dilakukan, diketahui bahwa nilai t hitung > t tabel adalah 2,04 > 2,00. Dengan demikian, dapat disimpulkan ada pengaruh model pembelajaran inkuiri terhadap hasil belajar siswa.

 

Abstract: This study aims to determine the effect of inquiry learning models on student learning outcomes on basic lathe material. This research method was pre-experimental pretest-posttest. The sampling technique used a purposive sample. The sample in this study was 28 students, students of class X TPM. The instrument used was a multiple choice test which amounted to 40 questions. Before the test questions are used, the instruments are tested for validity, reliability, distinguishing features, and the level of difficulty of the questions. Based on the results of data analysis that has been done, it is known that the value of t count > t table is 2.04> 2.00. Thus, it can be concluded that there is an influence of inquiry learning models on student learning outcomes.
Impact of Corrosive Substances on the Mucosa of the Digestive Tract
Authors: Birla Rodica Daniela , Hoara Petre Angel , Dinca Valeriu-Gabi , Dinca Alexandra-Ligia , Constantinoiu Silviu
Published: March 2020

Caustic ingestion is a major health concern in both developed and developing countries, that may lead to serious esophageal and gastric injury.Initially, the ingestion of a caustic substance produces post-caustic esophagitis, this being the acute phase, which in time by chronicization and by the methods of tissue remodeling, by fibrosis determines the post-caustic esophageal stenosis.
Food Neophobia in Preschool Children
Authors: Dop Dalia , Niculescu Elena Carmen
Published: March 2020

Food neophobia is generally considered as the reluctance to eat or the avoidance of new foods. Neophobia is not a permanent aversion to new food; acceptance can be promoted by repeated exposure or modeling the intake of the rejected food product.The study followed a number of 168 children aged between 2 and 5 years. The parents of the children filled a questionnaire regarding the physiological medical data of the children, the feeding habits (quantitative and qualitative). Neophobia was measured using the Child Food Neophobia Scale (CFNS). The study pursued the association between neophobia and the sex of the patient, the quality of the food products, the children�s diet (presence of fruits, vegetables), the weight of the patients, the duration of breastfeeding, the education level of the mother. Girls present higher scores on the CFNS scale than the boys. Children whose mothers have higher education were susceptible to having a higher variety of fruits in their diet. Children with a higher score on the CFNS scale and those with siblings were susceptible to having a lower variety of fruits and dairy products in their diet and a higher intake of fast-food products.The results highlight the necessity for early exposure of the children to a high variety of nutrient foods and the need to educate the parents with regard to the strategies needed in order to overcome food neophobia.
Fondant Candies Enriched with Antioxidants from Aronia Berries and Grape Marc
Authors: Opris Ocsana , Lung Ildiko , Soran Maria-Loredana , Sturza Rodica , Ghendov-Mosanu Aliona
Published: March 2020

Aronia berries and grape marc, a by-product of producing wine, are rich in antioxidants. The aim of this work was to study the effects of powders and extracts of aronia berries and grape marc addition on physico-chemical quality indicators, microbiological stability in vitro, and antiradical activity of fondant candies, during storage. In order to obtain the maximum antioxidant activity of the aronia berries and grape marc extracts, the Box-Behnken experimental design was used for optimization of the extraction method using sonication technique. During 35 days of storage, the dry mass fraction of all candies obtained significantly increased, which shows that the fondant candies obtained are stable over time. An important role was played by the antioxidant capacity of the plant materials used, whose chemical composition includes a number of biologically active substances which inhibit the development of microorganisms and allow stabilization of the fondant candies.
General Tendencies of the Behaviour of Vegetables Developed in a Soil Contaminated with Heavy Metals
Authors: Pruteanu Augustina , Vladut Valentin , Cardei Petru , Bordean Despina
Published: March 2020

The paper presents experimental results obtained in the study of heavy metals transfer from soil to vegetables. The experiments for which the raw and statistically processed data are presented in this paper are preliminary experiments within an extensive research program of plant behaviour in soils contaminated with heavy metals. These experiments underlie the development of primary statistical mathematical models that are also presented in the paper. These experiments will also form the basis for far more consistent experiments that follow plants throughout the life cycle. The statistical mathematical models presented in this paper facilitate extracting important conclusions about how plants accumulate heavy metals as well as about the accumulation rate behaviour during experiments. Both experiments and mathematical models will form the basis of complex experiments and dynamic mathematical models in the next stage of research.
An in vitro Evaluation of Apigenin and Apigenin-7-O-glucoside Against HeLa Human Cervical Cancer Cell Line
Authors: Minda Daliana , Avram Stefana , Pavel Ioana Zinuca , Kis Brigitta , Ghitu Alexandra , Zupko Istvan , Dehelean Cristina , Buda Valentina , Diaconeasa Zorita , Scurtu Alexandra , Vlad Alexa , Danciu Corina
Published: March 2020

pigenin (API) is a phytocompound belonging to the subclass of flavones that can be found in both functional foods as well as medicinal plants. Recent studies have assigned API antioxidant, anti-inflammatory, anti-spasmodic, anti-viral, anti-thrombotic, anti-angiogenic and chemopreventive potential in vitro on various cell lines and/or in experimental animal models. Apigenin-7-O-glucoside (API-7) is one of its main glycosides and can be commonly found in chamomile flowers, parsley, celery. The aim of this study was to evaluate the in vitro anti-proliferative and pro-apoptotic effects of API and its glycoside (apigenin-7-O-glucoside) against HeLa human cervical cancer cells. Results have shown that in the set experimental conditions both the aglycone as well as the heteroside elicit antiproliferative and pro-apoptotic potential against the screened cell line, the aglycone being more active than the heteroside.
Preliminary Study on Genotoxicity Assessment of an Innovative Topical Treatment for Periodontal Disease
Authors: Cristache Corina Marilena , Totu Eugenia Eftimie , Burlibasa Mihai , Tanase Gabriela , Iorgulescu Gabriela , Burlibasa Liliana
Published: March 2020

The aim of the present study was to assess the genotoxicity of three different antibacterial, antioxidant and anti-inflammatory mixtures: tetracycline (T) with metronidazole (MZ), melatonin (MEL) with hyaluronic acid (HA), and T+MZ+MEL+HA, in order to choose the best formulation to be used as topic treatment for periodontal disease. In vitro Micronucleus Test was performed (MTvit) according to Organization for Economic Cooperation and Development (OECD) 487 recommendations, in a blind mode, without knowing the composition of the powders evaluated. The highest cytotoxicity and incidence of MN was observed in T+MZ mixture and the mixed compounds T+MZ+MEL+HA, 1 mg/mL in the cell culture, registered the lowest incidence of micronuclei, meaning the lowest cytotoxicity, comparable to the negative control sample. Based on the present findings and previously published results, it can be concluded that the complex mixture T, MZ, MEL and HA showed excellent cytotoxicity profiles, with lower rate of chromosomal damage risk, and therefore, is recommended for safe use as topical treatment in periodontal disease.
Analysis of Comfort Indices and Their Impact on the Environment
Authors: Rusanescu Carmen Otilia , Rusanescu Marin , Begea Mihaela , Stoian Elena Valentina
Published: March 2020

In this paper, the following comfort indices and their implication on the environment are analyzed: the effective equivalent temperature index (TEE), the humidity temperature index (UTI) and the Thom discomfort index (DI Thom). These indices highlight the comfort or thermal discomfort of a region depending on the values for the air temperature, the relative humidity of the air during the period 2009-2018 recorded by the weather station AWWS/EV from the Faculty of Engineering of Biotechnical Systems, Politehnica University of Bucharest.
Effects of Patulin Treatment on Zebrafish (Danio rerio) Internal Organs
Authors: Mandalian Tigran-Lucian , Coprean Dragomir , Pasca Aurelian-Sorin
Published: March 2020

Patulin is a common contaminant of many food products which are part of humans or animals daily nutrition: fruits and fruit products, cereals, diary products and sausages. In the present study, adult zebrafish were divided in 2 groups: Control and patulin-treated group which was exposed to patulin (70 �g/L) for 7 days. Histological alterations of the control and patulin-treated group were examined and compared, with emphasis on liver, kidney, pancreas, intestine, brain and myocardium. While the Control group had no histological alterations, the patulin-exposed zebrafish show severe hepatocyte alteration, medium to severe degeneration of urinary epithelium, enterocytes hyalinosis, partial coagulation necrosis of the Langerhans islets and myocardial edema.
Influence of a Chromium-rich Industrial Waste on the Hydration and Hardening Processes of Portland Cements with Slag and Limestone Additions
Authors: Oproiu Carmen-Lidia , Parvan Marius-George , Voicu Georgeta , Badanoiu Alina-Ioana , Trusca Roxana
Published: March 2020

This research work assesses the influence of a chromium-rich waste (from potassium dichromate manufacture) on the hydration and hardening processes of two types of Portland cements with limestone filler and slag additions. Therefore, mixtures of Portland cement and chromium-rich waste, corresponding to 0.5% wt. and 1% wt. Cr, were prepared and tested. The analyses performed on cement pastes with chromium waste content, showed that chromium immobilization is mainly due to the formation of Ca6Al2Cr3O18�32H2O (CrEt); this compound results by the substitution of [SO4]2- groups from ettringite lattice of with [CrO4]2-. CrEt crystals growth on the surface of clinker particles forms a diffusion barrier which explains longer setting times for cements with chromium content. The increase of chromium content in the studied systems decreases the compressive strength values but these remain above the lower limits imposed for this type of materials. The chromium content in leachates prepared according to the method described in SR EN 12457-2, was well below the legal limit of 70 mg/Kg established by Romanian legislation. A better chromium immobilisation was achieved in the cement with slag content, in good correlation with the nature and amount of formed hydrates.
Green Synthesis of Silver Nanoparticles Using Hypericum perforatum L. Extract and Evaluation of Their Antibacterial Activity
Authors: Gitea Daniela , Teodorescu Andrei , Pantis Carmen , Tit Delia Mirela , Bungau Alexa Florina , Bogdan Mihaela , Fodor Ilona Katalin , Bustea Cristiana
Published: March 2020

Silver nanoparticles (AgNPs) ranging in size from 1-100 nm show good application potential in many medical fields (therapies, medical devices, molecular diagnostics) due to their antimicrobial properties. The purpose of this study is to characterize from physicochemical perspective the colloidal dispersion obtained through phyto-synthesis. The existence of colloidal silver particles was visually highlighted through Thyndall effect. The bio-reduction of silver ions was analyzed through modern techniques, UV-VIS spectrophotometry and Hyperspectral Microscopy. After getting the colloidal dispersion, its antibacterial activity was proved by sowing on different plates the following types of pathogenic agents: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. The UV-VIS spectrum for the methanolic extract with 10% H. perforatum L. and for the silver colloidal dispersions was achieved, observing a max at 455 nm. The hyperspectral images were achieved observing the shape, conformation, and the size of the obtained particles. During the antibacterial efficacy testing on those three strains of pathological agents, in all situations, the colloidal dispersion had a promising antimicrobial effect.
Immunohistochemical Analysis of Gingival Proliferative Processes Associated with Fixed Orthodontic Therapy
Authors: Simon Catalin Petru , Bratu Dana Cristina , Motoc Andrei Gheorghe Marius , Popa George , Pop Izabella Silvia , Mederle Ovidiu Alexandru
Published: March 2020

Our study started from the hypothesis that the gingival volume growth associated with fixed orthodontic treatment appeared during the use of leveling and aligning archwires, without any inflammatory signs, as a result of the mechanical stress and periodontal remodeling during the orthodontic dental movement.We selected and included in the study 35 patients (13 females and 12 males) between 12 and 38 years of age, all suffering from gingival overgrowth, diagnosed during the active treatment with fixed orthodontic appliances (braces). For each patient, two tissue samples were taken: one in the early stages of the lesion, coinciding with the use of leveling and aligning archwires and another in the late stages of the lesion, coinciding with the use of finishing archwires. The samples were taken from the same site in the oral cavity. Out of 35 gingival biopsies taken from patients, 8 cases showed no significant changes in the gingiva, while in the remaining 27 cases, significant changes were found after the histopathological exam.Out of 27 gingival biopsies, 16 cases presented a significantly greater number of T cells. In addition, a greater number of B cells were observed in the granulation tissues than in the gingiva. The relative number of B cells (CD20), T cells and dendritic cells (CD8) has been expressed, both in the early and the late stages of the gingival lesions. Our results revealed that the proportion of T lymphocytes and dendritic cells was greater in the early stages rather than at the late stages. The B cells showed a higher count in the late stages.
Differences on Biochemical Composition of GoatMilk at Carpathian Breed and Half Breed Saanen X Carpathian and French Alpine X Carpathian
Authors: Anghel Andreea Hortanse , Nadolu Dorina , Ilisiu Elena , Cismileanu Ana
Published: March 2020

The aim of our study was to evaluate the gradient of milk yield, of milk biochemical composition and fatty acids profile according to breed, for primipara goats from Carpathian breed and Saanen x Carpathian and French Alpine x Carpathian half breed that were grown in semi-intensive system (Dobrogea, South Romania).
The studies were performed on goats raised at ANCC CAPRIROM farm, located in Constanta, Romania. The biochemical parameters (fat, proteins, lactose) were studied by electrochemical method with a Lactostar analyzer Funke Gerber type specialized for goat milk. Milk fatty acids profile, as fatty acids methyl esters (FAME), was determined by chromatographically gas method. The considerable high protein content found in half breeds, might be explained by the fact that bucks from specialized breeds such us Saanen and French Alpine which were used for half breeding, come from imported animals from France, which were locus genotyped for alpha S1 casein gene and were selected dominant genotypes that lead to a higher protein concentration in milk.The statistical analysis shows that the milk coming from Carpathian does and their half breeds is not significantly different regarding the levels of various fatty acids, saving omega 3 acids, which are considerable higher at Carpathian does, proving that food has the decisive role regarding composition.
Air Medical Interventions at Comatose Pediatric Patients in Eastern Romania - Particularities of Airway Managementand Cardio-Pulmonary Resuscitation
Authors: Trifan Angel Liviu , Dragomir Liliana , Elkan Eva-Maria , Sapira Violeta , Lungu Mihaela , Zlati Monica , Papuc Ana-Maria , Florescu Laura , Miulescu Magda , Cimpoesu Diana Carmen , Nedelea Paul Lucian
Published: March 2020

Pediatric comas are particular situations of terrestrial or aerial medical intervention, requiring knowledge of specific protocols and prioritization and hierarchy of emergency interventions. The reactivity of the comatose child is modified according to multiple biological, physiological parameters and generating pathologies. The study aims to analyze the specific elements of aerial medical interventions with helicopter, HEMS (Helicopter Emergency Medical Service) at comatose child that influences the emergency path, but especially the medium and long term prognosis of these cases. The transfer of comatose children at Galati aeromedical base, both primary and secondary interventions, were studied. The study was a prospective randomized study involving pediatric comas transferred over a 4-year course (2014-2017) according to the criteria in force. A total of 24 children between the ages of 0-18 years were transferred, with primary and secondary interventions. In the study lot, the correlations between Glasgow scores and associated pathology, epidemiological characteristics, therapeutic elements, complications and case evolution were analyzed. A profile of the patient requiring emergency intervention for the comatose state was created, making it possible to predict the services they will need and to design the specialized interventions that will follow the transfer of these patients. Although still intensely disputed due to cost considerations, the air transfer of the comatose child facilitates a more prompt response of medical systems to manage this type of emergency and presents management particularities in pre-hospital. Based on this type of results, a strategy takes shape by which the Romanian emergency system aligns with the continuous improvement of life-saving interventions for children.
In vitro Evaluation of the Antiproliferative Effect, Cytotoxicity and Proinflammatory Activity of the Food Additive Monosodium Glutamate on RAW 264.7 Cell Line
Authors: Baciu Dora Domnica , Salageanu Aurora , Visan Teodor
Published: March 2020

Monosodium glutamate (E-621, abbreviated MSG) is a food additive widely used in the food domain as a flavor and taste enhancer. The present study aims to evaluate in vitro the effects of increased concentrations of MSG, using the RAW 264.7 murine macrophage line. The study was conducted in 3 complementary directions: first, establishing the ability of monosodium glutamate to induce cell mortality, by using the MTT assay to determine cell viability; second, establishing by its oxidizing activity if MSG is toxic for cells inducing oxidative stress, measured by the Griess test for determination of extracellular NO; third, to observe whether MSG presence induces an immune response quantified by the secretion of proinflammatory cytokines, TNFα in this case, measured through the immunoenzymatic ELISA technique.
Seasonality and Correlations between Water Quality Parameters in the Lower Danube at Chiciu for the Period 2010-2012
Authors: Frincu Rodica-Mihaela , Omocea Cristian , Eni Cerasela-Iuliana , Ungureanu Eleonora-Mihaela , Iulian Olga
Published: March 2020

The Danube River receives tributaries with different pollution loads, according to the social-economic characteristics of the adjacent regions. Water quality monitoring data from Chiciu, Calarasi county, Romania, for the three-year period (2010-2012), were analysed using statistical methods in order to identify correlations between parameters, as well as their evolution during the study period. The analysis has confirmedpositive correlations between nitrates and total nitrogen and between ortho-phosphates and total phosphorus. Negative correlations were found between water temperatures on one side and dissolved oxygen and nitrates on the other side. These parameters have a seasonal evolution, with high temperatures and low dissolved oxygen and nitrates levels during summer periods. Linear regression highlights decreasing nutrients pollution during the study period, which may be due to improved wastewater treatment along Danube tributaries.
Design, Synthesis, and Evaluation of Novel 3-, 4-substituted, and 3,4-di Substituted Quinazoline Derivatives as Antimicrobial Agents
Authors: El-Essawy Farag A. , Alharthi Abdulrahman I. , Alotaibi Mshari A. , Wahba Nancy E. , Boshta Nader M.
Published: March 2020

A novel series of 3-, 4-substituted, and 3,4-di substituted quinazoline derivatives were prepared via various cyclized regents and most of the newly prepared compounds evaluated for their antimicrobial activities in vitro against Gram-positive, Gram-negative bacterial strains and fungi strains. The structures of the quinazoline derivatives have been confirmed using spectroscopic analyses (IR, NMR, and EI-MS). Some of the synthesized derivatives displayed a moderate antimicrobial activity in comparison with reference drugs, for example compounds 13d, 15a, 17b, 18b, 18d, 25, and 29a-c. Among the synthesized compounds, the pyrimidoqunazoline derivative 6c elicited the highest activity.
Multi Sistem Pendidikan Pesantren dan Tantangan Masa Depan
Authors: Safradji Safradji
Published: March 2020

Pesantren or Pondok Pesantren are Islamic boarding school. According to onepopular tradition. As social institutions, pesantren have played a major role overthe centuries. They emphasise cores values of sincerity, simplicity, individualautonomy, solidarity and self-control. Young men and women are separated fromtheir familier, which contributes to a sense of individual commitment to the faithand close bonding to a teacher. Pesantren aim to deepen knowledge of Qur’an,particularly thruugh the study of Arabic, traditions of exegesis, the Sayings of theProphet, law and logic. The term pesantren derives from the root word santri orstudent – pe-santri- or the place of the santri. Pesantren provides to Indonesiancitizens at low cost; although today some modern pesantren charge higher feesthan previously, they are still significantly cheaper than non-pesantreneducational instittutions. The tradisional pattern was for students to work in theheadmaster’s rice fields in exchange for food, shelter, and education. Allpesantren are led by a group of teachers and religious leaders known Kyai. TheKyai is respected as teacher and devout man. Kyai also play important roles in inthe community as a religious leader and in recent years as a political figure.There are Kyai families that have a long history of serving in this role. Somecontemporary Kyai are the grandsons and great-grandsons of famous historialfigures who established well known pesantren
Peran Kepala Sekolah dalam Pengembangan Kurikulum PAI
Authors: Rohmani Abd. Hadi
Published: March 2020

In the world of education, the principal becomes one of the most important holders inthe success of an institution he leads. Therefore, in order to be an ideal institution, atruly competent school principal is needed, who knows the duties, functions andobligations as a school principal. Therefore, in this article, the role ofschool/madrasa principal will be discussed In developing PAI curriculum
Konsep Cahaya dalam Al-Qur’an
Authors: Azizah Dyah Nurul
Published: March 2020

An-Nur in the Qur’an is a familiar word. It was mentioned in many verses withdifferent context. An-Nur in each verse has a different meaning, then need to adeep understanding. The purpose of this study is to know the real meaning fromAn-Nur in the Qur’an use a semantic theory. Semantic of Al-Qur’an is an attemptto reveal the world view of Qur’an on some terms and vocabularies in Qur’anthrough a semantic analysis. The analysis process begins from research a basicmeaning and contextual meaning of An-Nur with some verses. The conclusions ofthis study is that the word Án-Nur in the Qur’an has three categories; 1) An-Nuras something to fight digression, 2) An-Nur as the religion from God, and 3) Godas An-Nur or the Highest Level of An-Nur. The word An-Nur in the Qu’an isalways mentioned in singular form, while the darkness (opposite) is alwaysmentioned in plural form. That shows there are many dark or bad things, such asa various kinds of immorality, but it will be defeated with the one of the light (An-Nur). God as the Highest Light, Eternal, True, and Everything
Pendidikan Akhlaq Aplikatif-Integratif pada Madrasah Ibtidaiyah di Rubaru Sumenep
Authors: Kulsum Ummi
Published: March 2020

Education of moral is education that is very important to instill moraland spiritual values in life that can foster character, behavior, and good moralsfor future. If education of moral is not instilled in students from an early age, itdoes not close the possibility that students will fall into something that is notdesired by the wider community. Research on "applicative-integrative educationof moral in Madrasah Ibtidaiya Rubaru Sumenep" was carried out because it wasbased on these concerns.This research used descriptive-qualitative method with aphenomenological approach, which is by going down directly to the researchlocation to search for the data needed. As for this study the population taken wasthe whole of students of Madrasah Ibtidaiyah Rubaru Sumenep in the 2018-2019Academic year by giving a number of questions to students randomly by means ofrandom sampling. The respondents I chose were students in grades 4, 5, and 6 ofMI Nurus Salam Pakondang Village, Rubaru District, Sumenep Regency. So thetotal sample that will be in the data amounted to 35 students. Primary datasources in this study were the results of interviews with school principals, vicecurriculim, and moral teachers in MI Nurus Salam, Pakondang village, Rubarusub-district, Sumenep district.The results showed a strong commitment from MI Nurus Salam torealize an applicative-integrative moral education in the sense that morallearning does not stop in the area of the concept of knowledge about morals, butthere are efforts to internalize, habituate, exemplify, and continue coaching.Moral development implemented at MI Nurus Salam includes twothings: First, by guiding moral behavior through religious activities, such asreciting Asmaul Husna, Yasin letter, followed by Duha prayer 30 minutes beforeentering class and reading short letters 10 minutes before the lesson begins. Thisactivity is a routine activity that must be followed by every student from grade 1 tograde 6.Second, Commemoration of Islamic holidays (PHBI), such as the Birthof the Prophet, Isra ’Mi'raj,‘ Ashura, and Ramadan activities, all of theseactivities as a medium in fostering student morals. In implementing thisapplicative-integrative moral education, all parties are involved in the routinecoordination and monitoring of moral behavior. As a form of evaluation, thevalue of moral behavior in MI Nurus Salam is coordinated by the homeroomteacher as a report card on the behavior, crafts and neatness based on reportsfrom each teacher
Endobiogenika: globalus požiūris į sistemų biologiją
Authors: Justaitytė Justina , Serapinas Danielius
Published: March 2020

Endobiogenika ir funkcijų biologija pagrįsta keturiomis mokslinėmis sąvokomis:1. Žmogaus organizmas yra sudėtinga visuma, susidedanti iš dalių: organų,audinių, ląstelių, branduolių ir genų, kiekviena jų užtikrina tikslų funkcionavimą ir šios organizmo dalys nuolat tarpusavyje sąveikauja.2. Endokrininė sistema valdo medžiagų (angliavandenių, baltymų, riebalų) metabolizmą ir vienu metu gali valdyti save, todėl endokrininė sistema laikoma pagrindine organizmo valdytoja.3. Endokrininė sistema lemia biožymenų (kraujo elementų: raudonųjų ir baltųjų kraujo kūnelių, neutroflų, limfocitų, eozinoflų, monocitų; fermentų, elektrolitų ir kt.) išskyrimą į kraujotaką.4. Šiuos biožymenis susiejus tarpusavyje, gaunami indeksai (pvz., lytinio santykio indeksas, adaptacijos indeksas), kurie padeda įvertinti, kaip audiniuose veikia hormonai.Straipsnyje apžvelgsime įvairių hormonų, biožymenų reikšmę psichoneuroendokrinologijoje bei žymenų tarpusavio santykį, kuris pagrįstas sistemų biologija ir atspindi endobiogenikos koncepciją.
THE RELATIONSHIP OF PSORIASIS TO SUICIDE: LITERATURE REVIEW
Authors: Slabadienė Margarita , Minikavičiūtė Karolina , Sauserienė Jolanta
Published: March 2020

Psoriasis is a chronic skin condition that affects almost 3% of world’s population and is associated with potential adverse effects on mental health. Patients with psoriasis have a higher risk of depression, anxiety and suicide than the general population. The aim is to review articles published in 2010–2019 based on relations of psoriasis and suicide and to provide recommendations for physicians most frequently confronted with psoriasis.
Paciento priežiūra ir mokymas prieš ir po kataraktos operacijos. Rekomendacijos bendruomenės slaugytojams
Authors: Šulinskaitė Kristina , Dringelytė Kristina , Daukintytė Erika , Micevičienė Ramutė , Ivaško Ivona , Spirgienė Lina
Published: March 2020

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Kam ir kada gali būti naudingas kairiojo prieširdžio ausytės uždarymas
Authors: Pranevičius Robertas , Morkūnaitė Kristina , Unikas Ramūnas
Published: March 2020

Prieširdžių virpėjimas (PV) išlieka dažniausias ritmo sutrikimas su kuriuo susiduriame klinikinėje praktikoje. Pacientai, kurie turi šį ritmo sutrikimą, turi žymiai didesnę insulto tikimybę, todėl jiems įprasta skirti vitamino K antagonistus (varfariną) arba tiesioginius geriamuosius antikoaguliantus (NGAK). Dėl pacientų jau esamo polimorbidiškumo tinkamai palaikyti terapinę hipokoaguliaciją sudėtinga, todėl galima kraujavimo rizika. Iki šiol sunkios būklės pacientai, kurie dėl gretutinių patologijų arba jau buvusių kraujavimo įvykių, negalėjo vartoti varfarino ir dėl to turėjo vartoti redukuotas NGAK dozes, gydymo aspektu vis sunkiau būdavo išlaikyti pusiausvyrą tarp didžiausios naudos ir mažiausios naujų komplikacijų rizikos pacientui. JAV maisto ir vaistų administracija (angl. American Food & Drug Administration, USFDA), reglamentuojanti ir aprobuojanti naujus gydymo metodus, 2015 m. kovo mėn. patvirtino kairiosios prieširdžio ausytės uždariklių (KPAU) naudojimą. Taigi, pacientams sergantiems nevožtuvinės kilmės prieširdžių virpėjimu ir negalintiems vartoti antikoaguliantų, oficialiai atsirado alternatyva – kairiosios prieširdžio ausytės uždarikliai. Deja, ilgą laiką klinikinės indikacijos implantuoti pacientui KPAU nebuvo aiškiai apibrėžtos ir nebuvo įvertintos intervencinės komplikacijos bei vėlyvieji rezultatai po uždariklio implantavimo. Neseniai atliktų didžiausių atsitiktinių imčių tyrimų (PREVAIL, PROTECT­AF) duomenimis, kairiosios prieširdžio ausytės uždariklio implantavimo procedūra yra efektyvi ir saugi. Tyrimai įrodė, jog sėkmingai atlikus uždariklio implantavimą, sumažėja insulto tikimybė, sumažėja kraujavimo ir mirties rizika lyginant su varfarinu. Esant pakankamam įrodymų kiekiui, 2019 m. gegužės mėn., Kauno klinikose pirmą kartą atlikta sėkminga kairiosios prieširdžio ausytės uždarymo procedūra. Išvada. Remiantis pasauline klinikine praktika ir pirmosiomis patirtimis Kauno klinikose, kairiosios prieširdžio ausytės uždariklio implantavimas yra saugi ir efektyvi procedūra.
Ekonomi, Ekologi dan Manajemen Dalam Menciptakan Sarana dan Prasarana Pendidikan Islam
Authors: Hafiz Muhammad
Published: March 2020

Keberhasilan sebuah lembaga pendidikan Islam tentunya diperlukan dari faktor ekonomi, ekologi, manajemen dan sarana prasarana yang memadai.  Agar sarana dan prasarana penididikan itu tercukupi dan relevan dengan kebutuhan, maka perluhnya pengkajian lebih jauh tentang pengelolaan sarana dan prasarana agar visi  dan misi dari sekolah tersebut dapat tercapai. Jenis  penelitian  yang  digunakan  dalam  penelitian  ini  adalah    penelitian kepustakaan (Library Research) yatu metode memperoleh data dari buku-buku yang relevan dengan penelitian tersebut yaitu buku dan jurnal yang membahas tentang ekologi, manajemen, sarana dan prasarana dalam pendidikan Islam Metode analisis yang digunakan dengan cara memilah-milah antara pengertian satu dengan pengertian yang lain untuk mendapatkan kejelasan dari hasil penelitian ini. Hasil penelitian menunjukkan bahwa ekonomi pendidikan Islam memberikan kontribusi terhadap keberhasilan proses pembelajaran sedangakan studi ekologi manusia dalam konteks pendidikan tidak lepas dari peranan manusia dan ekosistemnya yang melibatkan unsur, subjek, audien, materi, proses, media, tujuan dan efek.
MEMPERKUAT EKSISTENSI PENDIDIKAN ISLAM DI ERA 4.0
Authors: Syakhrani Abdul Wahab
Published: March 2020

Tulisan ini berupaya mendorong perlunya reformasi masif di tubuh pendidikan Islam. Reformasi ini diperlukan agar pendidikan Islam  mampu  menjawab  tantangan  dan  tuntutan  zaman yang terus mengalami perubahan. Selain itu, tulisan ini juga berupaya memberikan tawaran solutif kepada pendidikan Islam dalam menghadapi Era Revolusi Industri 4.0. Sebagaimana dikertahui bersama, bahwa era 4.0 membawa dampak yang luas dalam segala lini kehidupan, tak terkecuali dalam bidang pendidikan. Era yang melahirkan fenomena disruption ini menuntut dunia pendidikan Islam untuk turut menyesuaikan diri. Lulusan pendidikan Islam kini dihadapkan pada tantangan, tuntutan, dan kebutuhan baru yang belum pernah ada sebelumnya. Sehingga perlu dilakukan pembaruan dan inovasi terhadap sistem, tata kelola, kurikulum, kompetensi sumber daya manusia, sarana dan prasarana, budaya, etos kerja, dan lain-lain. Jika tidak demikian, pendidikan Islam akan semakin tertinggal dan usang. Oleh karena itu, perlu dicari langkah-langkah kongkrit bagi pendidikan Islam agar mampu tetap bersaing di era disrupsi ini. Langkah solutifnya adalah dengan turut mendisrupsikan diri.
SNAFU: The Semantic Network and Fluency Utility
Authors: Zemla Jeffrey C. , Cao Kesong , Mueller Kimberly D. , Austerweil Joseph L.
Published: March 2020

The verbal fluency task—listing words from a category or words that begin with a specific letter—is a common experimental paradigm that is used to diagnose memory impairments and to understand how we store and retrieve knowledge. Data from the verbal fluency task are analyzed in many different ways, often requiring manual coding that is time intensive and error-prone. Researchers have also used fluency data from groups or individuals to estimate semantic networks—latent representations of semantic memory that describe the relations between concepts—that further our understanding of how knowledge is encoded. However computational methods used to estimate networks are not standardized and can be difficult to implement, which has hindered widespread adoption. We present SNAFU: the Semantic Network and Fluency Utility, a tool for estimating networks from fluency data and automatizing traditional fluency analyses, including counting cluster switches and cluster sizes, intrusions, perseverations, and word frequencies. In this manuscript, we provide a primer on using the tool, illustrate its application by creating a semantic network for foods, and validate the tool by comparing results to trained human coders using multiple datasets.
Titta: A toolbox for creating PsychToolbox and Psychopy experiments with Tobii eye trackers
Authors: Niehorster Diederick C. , Andersson Richard , Nyström Marcus
Published: March 2020

We present Titta, an open-source toolbox for controlling eye trackers manufactured by Tobii AB from MATLAB and Python. The toolbox provides a wrapper around the Tobii Pro SDK, providing a convenient graphical participant setup, calibration and validation interface implemented using the PsychToolbox and PsychoPy toolboxes. The toolbox furthermore enables MATLAB and Python experiments to communicate with Tobii Pro Lab through the TalkToProLab tool. This enables experiments to be created and run using the freedom of MATLAB and Python, while the recording can be visualized and analyzed in Tobii Pro Lab. All screen-mounted Tobii eye trackers that are supported by the Tobii Pro SDK are also supported by Titta. At the time of writing, these are the Spectrum, Nano, TX300, T60XL, X3-120, X2-60, X2-30, X60, X120, T60 and T120 from Tobii Pro, and the 4C from Tobii Tech.
METODE NAÏVE BAYES UNTUK MEMPREDIKSI PENGGUNAAN LISTRIK RUMAH TANGGA
Authors: Fallo Diana Yanni
Published: March 2020

Penelitian ini menggunakan metode Naïve Bayes untuk memprediksi penggunaan listrik setiap rumah tangga di Kota Kupang. Metode ini menggunakan bahasa pemrograman PHP dan MySql database. Hasil penelitian menunjukkan bahwa pengujian terhadap 50 data di Wilayah Kota Kupang. Penggunaan listrik dengan jumlah daya 1300 VA dan 900 VA sebagai berikut : pada keluarga yang berpenghasilan kisaran 2 juta sampai 3 juta serta memiliki tanggungan keluarga 4-7 orang, dengan jumlah peralatan listrik cukup dan jumlah pemakaian bola lampu tinggi, maka keluarga-keluarga tersebut tidak perlu melakukan penambahan daya (cukup). Sedangkan, jumlah daya 450 VA pada kepala keluarga dengan penghasilan lebih dari 3 juta, serta memiliki tanggungan keluarga 4-7 orang, dengan jumlah peralatan listrik banyak (tinggi), dan jumlah pemakaian bola lampu tinggi maka keluarga-keluarga tersebut perlu melakukan penambahan daya (tambah daya). Hasil pengujian menemukan bahwa sebanyak 22 rumah tangga perlu melakukan penambahan daya (tambah daya). Sedangkan, 28 rumah tangga tidak perlu melakukan penambahan daya (cukup).