bluuebunny/crossref_metadata_2025 huggingface dataset:
Національна безпека та державна політика в сфері реалізації морського потенціалу України
Authors: Ніколюк О. В. , Седікова І. О. , Клевець М. В.
Published: April 2021

Географічний потенціал України на глобальному ринку морської торгівлі зовсім не реалізова-ний. Територіальне море (виняткова економічна зона країни) розмір якого трохи менший, ніж сухопут-на частина України, змушує з увагою ставитися до державного транспортного й іншого освоєння. Пор-това галузь відіграє ключову роль у зростанні української економіки. В Україні функціонує мережа па-ромного сполучення, морських контейнерних ліній. Однак морський фактор розвитку України ще недо-статньо осмислений, а вплив на розвиток всього народного господарства – недооцінений. Морськийпотенціал не використовується достатньою мірою, а для України, економіка якої залежить від рента-бельної участі в інтернаціональній спеціалізації праці, виключного значення заслуговує саме ця про-блема – проблема розвитку морського потенціалу країни як чинник її безпеки. Механізм залученняінвестицій у портову галузь включають, але не обмежуються договорами концесії, оренди, угодамипро спільну діяльність та іншими видами інвестиційних договорів, що укладаються на основі спеціаль-них процедур, визначених Законами України.
On the geometry of $Diff(S^1)$-pseudodifferential operators based on renormalized traces.
Authors: Magnot Jean-Pierre
Published: April 2021

In this article, we examine the geometry of a group of Fourier-integral operators, which is the central extension of $Diff(S^1)$ with a group of classical pseudo-differential operators of any order.
Several subgroups are considered, and the corresponding groups with formal pseudodifferential operators are defined.
We investigate the relationship of this group with the restricted general linear group $GL_{res}$, we define a right-invariant pseudo-Riemannian metric on it that extends the Hilbert-Schmidt Riemannian metric by the use of renormalized traces of pseudo-differential operators, and we describe classes of remarkable connections.
China’s Experience in the Process of Financial Globalization
Authors: Ryaskova Ekaterina
Published: April 2021

The article examines the country’s strategy to “enter” the process of financial globalization. China’s embrace of globalization differs from many countries. In globalization processes, the financial component began to play a key role, giving multidirectional impulses to the development of the world economy. Financial globalization has engulfed all developing countries, which began to deregulate financial markets and promote capital liberalization, exposing national systems to systemic risks. The author proves the nature of China’s policy of “entering” the process of financial globalization, alternative from other countries, and describes the stages of introducing restrictions on the flows of speculative capital, the development of the stock market, as well as step-by-step decisions of the authorities to liberalize the conditions for the entry of foreign capital into the country. The article proves that the “moderate” nature of China’s strategy, the late opening of financial markets gave positive results for the country’s economic growth and the stability of the financial system. At the moment, China is actively opening its economy to foreign investors and capital without “shocks” and sets itself the goal of becoming a player that forms the rules in the world market.
State Policy in Converging Technologies: International and Russian Experience in the Growth Strategies Development
Authors: Petrova Elena , Fokina Elena
Published: April 2021

The article presents a systematization of distinctions in the converging technologies state policy implemented by foreign countries. NBIC convergence represents a source of a new direction in economic growth, as well as new regional development risks, which require the elaboration of appropriate government policy instruments at all its levels. The authors conclude that effective regional or national innovation policy measures can act as triggers that result in enterprises and scientific organizations entering into a converging technological innovation process, which allow them to take advantage of new emerging markets and industry conditions. In this process, regional or national authorities can play an important role in improving the basic conditions for companies and research institutions in their search for possible application areas, as well as giving them an access to information about modern methods assessing the opportunities and risks associated with converging technologies. The article analyzes the problems and restrictions that enterprises and organizations face on the way to the implementation of NBIC technologies (for example, the lack of specific information about new market opportunities for implementing converging technologies, search and association with new partners outside the sectors where companies operate, etc.) The authors propose directions for the regional specific features analysis, which allow elaborating territorial development programs for implementing converging technologies. Statistical analysis of the digital technologies usage in Russia and cross-country comparison by these indicators carried out by the authors allow concluding that the importance of ICT in the national economy is constantly increasing. The ICT role in building internal business and information interaction between companies and partners is becoming especially important for Russian companies. The level of distribution of cloud services in Russian organizations is comparable to the average for the EU countries. In this area Russia is ahead of France, Germany, and Austria. The industries with the best digitalization rates include the financial sector, retail and communications. At the same time, there remains a significant gap between the achieved level of ICT penetration in Russia and the countries that lead in the broadband Internet access availability, presence in the networks, and the use of information systems.
Socio-Economic Development of Russia and Problems of Spatial Structuring
Authors: Molchanova Natalya
Published: April 2021

The transition to a new social order is accompanied by changes in the methodology and functioning of socio-economic systems. The modern period of the development of scientific research is characterized by a variety of recommendations and opinions of scientists on the strategy and tactics of managing economic development. It is difficult to reach a consensus in choosing the most effective means of economic policy, taking into account the peculiarities of the current internal and external situation. For the functioning of the national economy of Russia, it is important to reach a consensus in the applied methods and instruments of state regulation of economy in the territorial context: macroregions, regions, municipalities. The necessary conditions for the successful implementation of state plans and programs are the coordination of the activities of economic entities, production cooperation, and the stability of economic ties. The development and implementation of effective measures are relevant to current scientific problems and are in the center of public attention. The aim of the research is to study the features of spatial structuring in accordance with regional policy and national strategic documents, to conduct a content analysis of the socio-economic situation of Russian territories of different ranks. The expected result is the preparation of recommendations for the development of certain aspects of regional economic research. On the basis of factual material on federal districts, the work examines the possibilities of the practical application of methods and tools of regional economic science to achieve high results in business practice. Using general scientific and applied methods, a conceptual vision of the necessary changes in the priorities of spatial development and the system of strategic planning documents is presented. Based on the objective process of digitalization, current trends have been identified and possible innovations in approaches to structuring space at the subnational level have been formulated, and possible directions of transformation in the management of regional socio-economic systems have been substantiated.
Investigation of Borosilicate Glasses with Simulated HLW Components and Determination of Their Chemical Durability
Authors: Shaydullin S. M. , Belanova E. A. , Kozlov P. V. , Remizov M. B. , Dvoryanchikova E. M.
Published: April 2021

The paper discusses the current status of the HLW vitrification technology applied at the radiochemical plant of the Mayak PA. Conceptual and technical solutions proposed to develop the technology of vitrification of various types of liquid HLW at the Mayak PA are presented. Compositions of borosilicate glasses with HLW components are described, temperatures of their melting and easy pouring are determined. Chemical durability parameters obtained for the borosilicate glasses are provided.
Determination of phenolic compounds in medicinal preparations by galvanostatic coulometry
Authors: Yaschenko N. N. , Zhitar S. V. , Zinovjeva E. G.
Published: April 2021

In this work, the possibility of using reactions of electrogenerated titrants with phenolic compounds was studied and a method for their coulometric determination in medicaments by galvanostatic coulometry was developed. The research objects were: rutin, salicylic acid and drugs containing phenolic compounds such as «Ascorutin», «Salicylic Paste» and «Salicylic Ointment» of Russian manufacture. Electrogenerated halogens (Cl2, Br2 and I2) and hexacyanoferrate(III)-ions were used as titrants. It was found that for the quantitative determination of phenolic acids, the optimal reagent is electrogenerated bromine, for rutin - electrogenerated bromine and iodine, and for ascorbic acid - any of the studied electrogenerated titrants (Cl2, Br2, I2 and [Fe(CN)6]3-). The correct definition was checked by the «entered-found» method, the error does not exceed 2%. As experimental studies have shown, our method of coulometric titration with electrogenated bromine and iodine is characterized by good reproducibility of results, expression, accuracy and can be used to determine phenolic compounds in drugs, for example, «Ascorutin» tablets. It should be noted that by our procedure it is possible to determine the spectrum of phenol-containing compounds (rutin, ascorbic and salicylic acids) in drugs without their preliminary separation. Therefore, the coulometric method using electrogenerated titrants can be recommended for the determination of salicylic, ascorbic acids and rutin in dosage forms. The proposed method is accurate and eliminates the experiment error in comparison with the Pharmacopoeic method.
The development of technology for production of zeolites from fly-ash from Troitskaya power plant
Authors: Snegirev V. A. , Yurk V. M.
Published: April 2021

The study examines the technology of processing fly ash from Troitskaya power plant for the production of zeolite. The paper presents the results of laboratory studies evaluating the suitability of fly ash from Troitskaya power plant for the production of zeolites and the development of the zeolite production process. Fly ash contains a small amount of heavy metals that can complicate processing, but contains a large amount of silicon oxide. The technology consists of high-temperature alkaline activation of fly ash and hydrochemical synthesis. The resulting powder has a specific surface area of 89.7 m2/g, determined by the BET method, and an average pore diameter of 0.345 μm. The static exchange capacity was 220 mg/g.
Taxonomia das diretrizes para educação nos planos de governo dos elegíveis à Presidência da República Brasileira (2018)
Authors: Dias Lázaro Cezar , Oliveira Sibele Vasconcelos de , Pauli Rita Inês Paetzhold
Published: April 2021

Resumo: Compreendendo a importância da política e da participação pública no fortalecimento e legitimidade de estados democráticos, o artigo tem por objetivo analisar as diretrizes para educação dos planos de governo dos cinco candidatos mais votados na eleição presidencial brasileira em 2018. O uso da metodologia fuzzy é justificado pela grande aplicabilidade do método nas áreas das ciências sociais, sendo capaz de mapear quali e quantitativamente as informações e detalhamento das propostas. Sugere-se uma taxonomia, a qual dá um passo adiante em comparação à tradicional lógica booleana. Ressaltam-se como resultados: (i) preponderantemente, as diretrizes analisadas estão contidas em conjuntos mormente e eminentemente políticos; (ii) apenas dois candidatos dedicaram-se mais ao critério “Gestão democrática e participativa dos espaços educacionais”; (iii) proposições de candidatos que se aproximam de um espectro político à direita foram qualificadas como mormente e/ou eminentemente políticas e as de candidatos que se aproximam da esquerda, mormente e/ou eminentemente técnicas. Assumindo que tais propostas impactam diretamente na atuação governamental, é urgente e recomendado que os elegíveis exerçam um tratamento legítimo e responsável dessa etapa da formação de agenda de políticas públicas para que as desigualdades sociais, lato sensu, sejam atenuadas ao longo das próximas décadas.
Indicadores de qualidade em terapia nutricional enteral: aplicação em idosos internados em uma unidade de terapia intensiva
Authors: Feitosa Gina Araújo Martins , Barbosa Janine Maciel , Alves Gislayne Azevedo de Campos , Oliveira Narjara Cinthya Nobre de , Florêncio Márcia Virgínia di Lorenzo , Pedrosa Ivanilda Lacerda
Published: April 2021

Resumo Objetivo Investigar os indicadores de qualidade em terapia nutricional enteral em idosos internados em unidade de terapia intensiva de um hospital universitário em João Pessoa, PB, Brasil. Métodos Estudo seccional, retrospectivo, realizado no período de março de 2018 a março de 2019. Os indicadores utilizados foram frequência de: medida de Índice de Massa Corporal (IMC) à admissão; estimativa de gasto energético e necessidade proteica; administração adequada do volume prescrito x infundido; pacientes em jejum antes do início da terapia nutricional enteral; diarreia e constipação intestinal conforme os parâmetros do International Life Sciences Institute do Brasil. Para a comparação entre os indicadores de qualidade e os desfechos clínico (alta hospitalar e óbito) e tempo de internação (≤14 e >14 dias), utilizou-se o teste do qui-quadrado, sendo consideradas significantes as associações com p< Resultados Foram 79 idosos com tempo de internação médio de 14 dias. Em relação aos indicadores, a frequência de medida de IMC à admissão e a estimativa de gasto energético e necessidade proteica atingiram as metas. Quando analisada a associação dos indicadores de qualidade com desfechos clínicos, observaram-se diferenças significativas (p=0,010) entre o indicador volume infundido x prescrito e alta hospitalar. Conclusão A frequência de administração adequada do volume prescrito x infundido teve associação significativa com desfecho sugerindo que esse seja um indicador a ser considerado no monitoramento da assistência nutricional de pessoas idosas, sendo, portanto, necessária a elaboração de planos de ação para garantir a efetividade dos processos, porém são necessários mais estudos.
Primary health care nurses: attitudes towards the person with mental disorder
Authors: Nóbrega Maria do Perpétuo Socorro de Sousa , Fernandes Carla Sílvia Neves da Nova , Zerbetto Sonia Regina , Sampaio Francisco Miguel Correia , Carvalho José Carlos , Chaves Suellen Cristina da Silva
Published: April 2021

ABSTRACT Objective To identify the attitudes of nurses working in Primary Health Care towards the person with mental disorder and the variables related to health care provided. Methodology Descriptive, correlational study with 250 nurses from 69 Basic Health Units in the city of São Paulo. Data collection took place between April and August 2019 using the “Opinions about Mental Illness” scale. The data were analyzed using the KrusKal-Wallis test, with a 95% confidence level and statistical significance of p <0.05. Results The global mean of the scale was 197, which shows negative attitudes especially in the dimensions of Authoritarianism (44.6), Social Restriction (42.0), and positive in the dimension of Benevolence (51.7). Conclusion Nurses tend to have a stigmatizing attitudinal profile. It is necessary formative and permanent intervention so that it is possible to reduce stigma and improve community-based care recommended in the guidelines of the Psychosocial Care Network.
Análise sobre a estrutura urbana nos planos urbanísticos recentes de São Paulo (1968 - 2016)
Authors: Bernardini Sidney Piochi , Sato Priscila Regina
Published: April 2021

Resumo O artigo tem como objetivo apresentar uma análise transversal das propostas de estrutura urbana estabelecidas nos planos formulados para o município de São Paulo entre 1968, com o Plano Urbanístico Básico (PUB), e 2016, com a instituição da Lei de Uso e Ocupação do Solo mais recente. O PUB foi considerado como ponto de partida por conter, na sua concepção, aspectos relevantes do pensamento sobre planejamento urbano paulistano e a definição clara de uma estrutura urbana futura. A pesquisa buscou fazer esta análise comparativa considerando os conteúdos gráficos utilizados nos planos selecionados. A semiologia gráfica foi o método utilizado para construir esquemas conceituais que padronizassem as propostas, buscando trazer maior precisão quanto ao posicionamento conceitual estabelecido, demonstrando, por um lado, como os modelos teóricos, nos momentos em que os planos foram elaborados, dialogaram com as problemáticas socioeconômicas e, de outro, como foram recorrentes ao longo do tempo.
Phasing out the pre-transplant cytotoxicity crossmatch: Are we missing something?
Authors: Abud Jamile , Pupo Bruna Brasil Dal , Silva Cynthia da , Keitel Elizete , Garcia Valter Duro , Manfro Roberto Ceratti , Neumann Jorge
Published: April 2021

Abstract Introduction: The anti-human globulin-enhanced complement-dependent cytotoxicity crossmatch (AHG-CDCXM) assay has been used to assess the presence of donor-specific antibodies (DSA) in recipient’s serum before kidney transplantation. The flow cytometric crossmatch (FCXM) assay was first introduced as an additional test. The aim of this study was to clinically validate the single use of the FCXM assay. Methods: This study compared the outcomes of a cohort of kidney transplant patients that underwent FCXM only (FCXM group) versus a cohort of kidney transplant patients that underwent AHG-CDCXM (control group). Results: Ninety-seven patients in the FCXM group and 98 controls were included. All crossmatches in the control group were negative. One patient in the FCXM group had a positive B cell crossmatch. One year after transplantation, there were no significant differences in patient survival (p = 0.591) and graft survival (p = 0.692) between the groups. Also, no significant difference was found in the incidence of Banff ≥ 1A acute cellular rejection episodes (p = 0.289). However, acute antibody-mediated rejections occurred in 3 controls (p = 0.028). Conclusion: The results showed that discontinuing the AHG-CDCXM assay does not modify the clinical outcomes in a 1-year follow-up.
A teoria contemporânea do restauro e as cerâmicas arqueológicas da Amazônia
Authors: Maia Lorena Porto , Sanjad Thais Alessandra Bastos Caminha , Lima Helena Pinto
Published: April 2021

Resumo Este artigo apresenta uma discussão acerca das intervenções de conservação e restauro realizadas em cerâmicas arqueológicas, com ênfase no acervo do Museu Paraense Emílio Goeldi (MPEG), localizado em Belém, Pará, região Norte do Brasil. A pesquisa tem como principal objetivo a identificação dos tipos de restauro encontrados na reserva técnica do MPEG e a aplicabilidade da teoria contemporânea do restauro na intervenção da cerâmica arqueológica. Para o desenvolvimento da pesquisa, foram analisadas as principais teorias de restauro e políticas preservacionistas do Brasil. Em seguida, reconheceu-se os valores culturais das cerâmicas arqueológicas e seu significado para a sociedade civil. Por fim, foram analisadas as intervenções restaurativas identificadas no acervo do MPEG, de modo a discutir sua trajetória ao longo do tempo. Ademais, debate-se sobre as reflexões pré-intervenções necessárias, de modo a determinar a intenção da restauração e as técnicas ideais para a salvaguarda do bem cultural.
Relações de objeto em Canela
Authors: Alves Flávia de Castro
Published: April 2021

Resumo O Canela é a língua falada pelos povos Canela Apa?niekrá e Canela Ramkokamekrá (cerca de três mil indivíduos) que habitam duas terras indígenas (Área Indígena Porquinhos e Área Indígena Kanela, respectivamente), localizadas no estado do Maranhão. Neste artigo, distingo inicialmente os sintagmas posposicionais que são (semanticamente) argumentos e os que são adjuntos em Canela (família Jê, tronco Macro-Jê). A seguir, identifico os argumentos definidos como o paciente (P), o tema (T) e o recipiente (R), e apresento suas respectivas propriedades gramaticais (codificação, comportamento e controle). A conclusão é de que P e T são o objeto direto, enquanto R (de verbos como ‘dar’, ‘contar’ e ‘mostrar’), lexicalmente especificado, é o objeto indireto.
Reconstrução atípica de laringe: avaliação funcional pós-laringectomia supratraqueal ampliada com cricoglossohioidopexia
Authors: Zica Guilherme Maia , Santos Izabella Costa , Dias Fernando Luiz , Freitas Emilson Queiroz , Freitas Andressa Silva de
Published: April 2021

RESUMO Em tumores transglóticos estendidos para base de língua, a indicação para ressecção do osso hioide descarta a possibilidade de realização de uma laringectomia parcial horizontal clássica, devido ao grande risco de complicações pulmonares oriundas de uma disfagia grave. O objetivo deste estudo foi descrever os aspectos funcionais de deglutição e voz de um paciente submetido à laringectomia supratraqueal ampliada com cricoglossohioidopexia. Trata-se de um homem de 69 anos, com tumoração transglótica na hemilaringe direita, submetido à laringectomia supratraqueal ampliada, com ampliação para base de língua, osso hioide e aritenoide direita. Na videofluoroscopia da deglutição, observou-se aspiração silente para líquido fino durante a deglutição e resíduo em base de língua, valécula, aritenoide, esfíncter esofágico superior e recessos piriformes em todas as consistências e volumes. Na videolaringoscopia, observou-se voz por meio da vibração da unidade cricoaritenóidea esquerda, associada à base de língua e constritores da faringe. No protocolo Consensus Auditory-Perceptual Evaluation of Voice (CAPE V), notou-se grau moderado de rouquidão e soprosidade. O paciente apresentou preservação parcial das funções laríngeas, grau moderado de disfonia e alimentação e hidratação exclusivas por via oral, com sólidos macios e líquido espessado em néctar, sem prejuízos à saúde pulmonar, até o momento.
Jogo InterRaps: uma estratégia de ensino interprofissional em Saúde Mental
Authors: Silva Mariana Nunes da , Polmonari Natalia Donato , Castro Davi Fernandes de , Oliveira Édina Siméia Campos de Siqueira de , Lourenço Rafaela Gessner
Published: April 2021

Este artigo tem por objetivo relatar a experiência da criação do jogo de tabuleiro InterRaps, sobre a Rede de Atenção Psicossocial, como estratégia de ensino interprofissional para estudantes de graduação da área da Saúde. A estratégia foi desenvolvida no contexto do Programa de Educação pelo Trabalho em Saúde realizado em uma universidade pública de Curitiba, PR, Brasil. O desenvolvimento compreendeu três etapas: definição da proposta; definição do desenho e da dinâmica; e criação do protótipo. No jogo de caráter educativo, os alunos resolvem estudos de caso e exercitam conhecimentos sobre os equipamentos da Rede de Atenção Psicossocial (Raps). Tal jogo relaciona teoria e prática, com questões baseadas na legislação vigente e casos que simulam a realidade, abordando os desafios encontrados pelos profissionais. O jogo InterRaps possui potencial para promover o ensino interprofissional e aprendizado colaborativo e despertar a reflexão acerca da temática.
Visibilidad de los sanitarios durante la crisis del Covid-19: estudio de fuentes y temáticas en los informativos de televisión
Authors: Rebolledo Marta , González Hildegart , Olza Inés
Published: April 2021

Esta investigación analiza la cobertura mediática de la crisis del Covid-19 en España, y el papel que en ella ha tenido la comunicación sobre salud y sobre los profesionales sanitarios. Se estudia el tratamiento recibido por las fuentes y temas sanitarios en los informativos de Radiotelevisión Española (RTVE) emitidos entre el 31 diciembre 2019 y el 8 junio 2020. Para ello, se realiza un análisis de contenido cuantitativo de 452 noticias de 21 informativos. Los resultados muestran que los debates de política y los propios políticos ocupan más espacio como tema y fuentes, respectivamente, en los informativos analizados, por delante de la salud y de los profesionales sanitarios. El estudio confirma, por tanto, la falta de visibilidad de los profesionales de salud en la cobertura informativa televisiva en España sobre el Covid-19.
The role of VES-13 to identify limited life expectancy in older adults in primary healthcare settings
Authors: Assis Danilo Lopes , Chagas Virgínia Oliveira , Saulo Helton , Suemoto Claudia Kimie , Santana Alfredo Nicodemos Cruz
Published: April 2021

ABSTRACT Objective To investigate the potential role of the Vulnerable Elders Survey to identify older adults with limited life expectancy in primary healthcare settings. Method This cross-sectional study was performed in all (nine) healthcare units in Jatai, Goiás (Brazil) from July to December 2018. A sample size of 407 older adults was obtained considering an older population (≥ 60 years old). Participants answered a questionnaire about sociodemographic and clinical characteristics, including the Vulnerable Elders Survey and the Suemoto index. We tested the association between limited life expectancy and the Vulnerable Elders Survey using multiple logistic regression analysis. Results The mean age was 68.9 ± 6.6 yo, and 58.0% were women. The mean score of the Vulnerable Elders Survey was 2.0 ± 2.2, the mean score of Suemoto index was 31.5 ± 21.1%, and 17.2% had limited life expectancy. The Vulnerable Elders Survey was associated with limited life expectancy (OR = 1.57; p = < 0.0001). Conclusion The Vulnerable Elders Survey was able to identify older adults with limited life expectancy in primary healthcare settings and can play a role in detecting older adults who would not benefit from screening and strict control of chronic diseases.
Layering effects of sand samples prepared by travelling pluviators
Authors: Zhang Zhiyong , Chian Siau Chen
Published: April 2021

Travelling pluviators have been commonly adopted to prepare large-scale laboratory sand samples for higher efficiency and consistency. Despite several literature reviews investigating the superiority of such travelling pluviators being able to produce repeatable models, the complex interdependence of the operating variables, in particular travelling speed, on the prepared sand model has not been fully understood to date. In this study, various operating variables of the pluviator – the falling height, deposition intensity (i.e. sand flow rate from orifice) and travelling speed – are studied with three types of sands prepared to desired densities. Through a proposed hypothesis based on energy, the travelling speed was found to have little impact on the sand particles’ kinetic energy for deposition; the influence of the travelling speed on the relative density is realised by altering the layer thickness during pluviation. In addition, it is worth noting that, although the global uniformity can be achieved by preparing sand models in layers in a consistent manner, there exists non-uniformity within each pour in the vertical direction due to particles segregation. This study provides such detail by direct observation of the particle segregation within the layer and the extent of the disturbance by boundary effect of the container.
Optimisation of vibroflotation by amplitude in 1g tests and coupled Eulerian–Lagrangian simulations
Authors: Nagula Sparsha Sinduri , Katt Justus , Grabe Jürgen
Published: April 2021

Vibroflotation includes densification of loose sands by means of shear deformation processes imparted by horizontal vibrations of vibrator probes. 1g model tests replicating the vibroflotation process were conducted using a model vibrator to identify online compaction control parameters. The effectiveness of the compaction was evaluated by means of a cone penetration test. An accelerometer and a trigger were installed in the model vibrator to measure the amplitude of the vibrator and the phase angle of the eccentric mass during compaction. The variation of amplitude and phase angle during compaction was studied and it was observed that amplitude and phase angle reduced with the increasing density of sand. Two tests were conducted with and without considering amplitude as a compaction control parameter. One test included a pre-determined fixed compaction time and the other used amplitude as a compaction completion indicator. It was observed that tests conducted considering amplitude as a compaction control parameter led to reduced compaction time. Coupled Eulerian–Lagrangian-based numerical simulations were carried out to study the feasibility of amplitude-controlled compaction under realistic stress state conditions.
Writing as a Religious Lieu de Savoir
Authors: Hoogvliet Margriet , Corbellini Sabrina
Published: April 2021

Taking its start from the analysis of the notion savoir-pouvoir in Foucault's philosophical work, the article discusses the applicability of the concept lieux de savoir in the study of writing activities in late medieval France and Italy performed by non-professional vernacular scribes. The act of copying a text is evaluated as an active contribution to the dissemination of religious texts. It is approached as a social act and process, which creates a communication circuit facilitating the flow of information within a textual community created by the very same act of writing. The approach to lieu de savoir as an activity, in which a process-oriented methodology is preferred to a material one, paves the way for new applications of the concept, in which the spaces, the objects and the actors are studied in a continuous exchange and dynamic.
Çocuk Endokrinoloji Bakış Açısıyla Yeni Koronavirüs Hastalığı
Authors: ATAR Müge
Published: April 2021

Tüm dünyayı sarsan yeni koronavirüs hastalığının erişkin çağda endokrinolojik hastalığı olan bireylerde daha ağır seyrettiği bilinmektedir. Çocukluk çağında obezitenin yüksek mortalite oranları ile ilişkisi öne sürülmektedir. Diyabet ekibi ile yakın iletişim halinde olması gereken Tip 1 diyabet (T1D) tanılı hastaların uzaktan eğitim ve teletıp yöntemleri ile desteklenmesi gerekmektedir. Adrenal yetmezlik ve T1D nedeniyle izlenen hastalar enfekte olmaları halinde özel yaklaşımlarla tedavilerinde değişikliklere gereksinim duyacaklardır. Karantina kuralları gereği rutin alışkanlıklarının dışına çıkan çocuklarda obezite sıklığında artış, bunun bir sonucu olarak da puberte prekoks sıklığında artış görülmektedir. Çocuklara evde dahi olsa egzersiz yapılması, sağlıklı beslenme rutinlerinden uzaklaşmamaları gerektiği hatırlatılmalı, çocuklar bu konuda desteklenmelidir.
COVİD-19 HASTALARINDA PULMONER REHABİLİTASYON
Authors: SOYUPEK Feray
Published: April 2021

COVID-19 hafif pnömoniden septik şoka kadar ilerleyebilen bir klinik spektruma sahiptir. Akciğer tutulumu, uzun süren immobilizasyon, fiziksel performans ve kas gücünde azalma, eşlik eden psikososyal bozukluklar rehabilitasyon ihtiyacını ortaya çıkartmaktadır.. Ana tutulum hedefi pulmoner sistemi olan bu hastalıkta pulmoner rehabilitasyonun (PR) yeri kaçınılmazdır. COVID-19’da PR’un yeri ile ilgili veriler gitgide artmakta, konsensüs raporları, öneriler şeklinde yayınlar rapor edilmektedir.
Single cell RNA sequencing library preparation (2-level sci-RNA-seq) v1
Authors: Srivatsan Sanjay , Cao Junyue
Published: April 2021

Sci-RNA-seq is a protocol developed by Junyue Cao in the Shendure Lab at the University of Washington and adapted by others in the Shendure and Trapnell labs. The protocol It is among a family of protocols that leverages split-pool barcoding for single cell sequencing.
Flow Cytometry Staining Protocol For Initial Kidney Studies v1
Authors: Lombardo Jeremy
Published: April 2021

Protocol for flow cytometry cell staining for initial kidney studies
HTAPP_Test protocol__Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using collagenase 4 and Liberase TM) v1
Authors: Slyper Michal , Waldman Julia , Napolitano Sara , Vigneau Sébastien , Rotem Asaf , Johnson Bruce , Rozenblatt-Rosen Orit , Regev Aviv
Published: April 2021

This protocol was used as part of the Human Tumor Atlas Pilot Project’s (HTAPP) efforts to establish a working protocol for the dissociation of human neuroblastoma core needle biopsies to a single-cell suspension compatible with droplet-based single-cell RNA-Seq technology. It is a testing protocol and we do not recommended using it for the intended purpose. Instead, for processing human neuroblastoma tumors, we recommend using the papain-based protocol established by Patel et al.
HTAPP_Test protocol__Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using collagenase 4) v1
Authors: Napolitano Sara , Slyper Michal , Vigneau Sébastien , Rotem Asaf , Johnson Bruce , Rozenblatt-Rosen Orit , Regev Aviv
Published: April 2021

This protocol was used as part of the Human Tumor Atlas Pilot Project’s (HTAPP) efforts to establish a working protocol for the dissociation of human neuroblastoma core needle biopsies to a single-cell suspension compatible with droplet-based single-cell RNA-Seq technology. It is a testing protocol and we do not recommended using it for the intended purpose. Instead, for processing human neuroblastoma tumors, we recommend using the papain-based protocol established by Patel et al.
Enhanced in vitro Shoot Regeneration and Biochemical Properties of Stevia rebaudiana using Chitosan
Authors: TANG CHU-NIE , LAMASUDIN DHILIA UDIE , WAN ABDULLAH WAN MUHAMAD ASRUL NIZAM , MOO CHEW-LI , CHIEW MIAO-SI , CHAI QIAN-YEE , ONG-ABDULLAH JANNA , LAI KOK-SONG
Published: April 2021

Stevia rebaudiana is a herbaceous perennial plant with great global demand due to its beneficial steviol glycosides(SGs) content. Current conventional breeding technique is unable to cater the need for more S. rebaudiana planting materials. Therefore, an improved in vitro shoot regeneration protocol was developed for S. rebaudiana by using chitosan. The highest fresh weight of plant (0.586 ± 0.176 g/explant), dry weight of plant (0.056 ± 0.02 g/explant) and plant height (4.94 ± 1.17 cm/explant) with maximum number of leaves (25.33 ± 6.95 /explant) were observed on explants grown in optimun treatment of MS basal medium supplemented with 1.0 mg/L of 6-benzyaminopurine (BAP) and 60 mg/L of low molecular weight (MW) chitosan after 4 weeks of culture. Scanning electron microscopy (SEM) analysis showed that new shoot primordia and shoot bud formation can be seen as early as day 3 and 5 of cultures on optimun treatment. Further biochemical assays showed that total phenolic acid content, total protein content and total hydrolyzed sugar content were recorded higher in explants cultured in optimun treatment as compared to control media. In contrast, total chlorophyll content and total flavonoids content were reduced in optimum treatment. Meanwhile, no significant difference in antioxidant activity was observed. All cultures from the optimal treatment were successfully regenerated, acclimatized and grew well with 100% survival rate. Taken together, an enhanced and efficient shoot regeneration protocol of S. rebaudiana was successfully developed which will be useful for rapid and large-scale micropropagation in future.
Acute Toxicity Evaluation of a Crude Sap Isolated from Nypa fruticants Wurmb. in Sprague Dawley Rats
Authors: YAHAYA SITI FATIMAH ROQIAH , SAMSUDDIN NIZA , MAMAT SUHANA , HOD ROZITA , ABDULLAH NOR ZAMZILA , A RAHMAN NOR AZLINA
Published: April 2021

Nypa fruticans Wurmb. (nipa palm) sap, locally known as air nira or tuak, is a sweet natural beverage in Malaysia with antioxidant potency beneficial for human health. However, nypa sap lacks scientific attention with no toxicity study has been established. Therefore, this study was performed to evaluate the acute toxicity of nypa sap in the female Sprague Dawley rats. Twenty-five female rats were randomly divided into one control group and four treated groups. Treated groups were orally administered with doses of 5, 50, 300, and 2000 mg/kg of nypa sap, while the control group had received normal saline solution. The animals’ vital signs and mortality were recorded daily at an interval of 30 min and continued up to 14 days. Their blood samples and organs were harvested for toxicity analysis to assess liver and kidney function, lipid profile, and full blood count. The acute toxicity test via measurement of the biochemical and haematological parameters had shown that there was no significant difference between the treated and control groups. However, the blood glucose level in the treated groups (at higher doses of 300 and 2000 mg/kg, respectively) was significantly decreased. A similar trend was recorded for mean corpuscular volume (MCV) albeit in the treated group of 50 mg/kg doses. Histopathological examination of the organs showed no signs of abnormality in both treated and untreated groups. Overall, the results showed that consumption of nypa sap is potentially safe with no acute toxic effect on the laboratory rat models.
A Comparative Study of Microwave-Assisted and Conventional Heating Methods of the Synthesis of 1-(Naphthalene-1-Yl)-3-(O, M, P-Tolyl)Thioureas, DFT Analysis, Antibacterial Evaluation and Drug-Likeness Assessment
Authors: SAPARI SUHAILA , ZAKARIAH EMMA IZZATI , ABDUL RAZAK NURUL HIDAYAH , RAMZAN INSYIRAH , NUMIN MOHD SOFI , LEE YOOK HENG , HASBULLAH SITI AISHAH
Published: April 2021

New isomers of naphthalene-monothioureas, 3a-3c, were synthesized and characterized by using infrared (IR), 1H and 13 C nuclear magnetic resonance (NMR) and mass spectroscopies (MS). The compounds were obtained from the reaction ofo-, m-, p- toluidine with naphthyl isothiocyanate using conventional reflux and microwave-assisted irradiation methods. Microwave-assisted reaction gave higher yields with reduces the reaction time compared to the conventional heating method. Density Functional Theory (DFT) calculations with 6-31G(d, p) basic set at the B3LYP level is carried out to optimize the structure of isomers and calculate the IR, 1H and 13 C NMR spectra. The DFTB3LYP calculation of FTIR, 1H and 13C NMR spectra of 3a-3c isomers were in accordance with the experimental data. The calculation of frontier molecular orbitals was also selected to study a relationship as a molecular descriptor in antibacterial activity. The isomers were screened for their in vitro antibacterial activity by using Staphylococcus aureus bacteria. Inhibition activity was displayed for compound 3c with the value of inhibition zone 7 ± 0.34 mm at a concentration of 10 μg/mL. All compounds appeared to be in agreement with Lipinski’s rule of five assessments as they adhered to most of the rules that can be preliminarily classified as active drug-like.
Mobbing process as a psychosocial risk factor in educational groups
Authors: Chaika Victoria N. , Mashtakov Vladislav A. , Matorina Olga S. , Streltsov Oleg V. , Meretukova Oksana G.
Published: April 2021

The socio-psychological phenomenon of mobbing in educational groups requires a detailed study and identification of new factors and dependencies. The purpose of this study is to analyze statistical information, identify the features of the formation and development of the mobbing process in the student team, and develop relevant techniques for timely response at any stage of the mobbing process. The article discusses the results of research by domestic and foreign authors on the problems of mobbing. A brief overview of the history of the term is given. Participants are identified and the main prerequisites for the formation of the mobbing process are identified. In accordance with the stages of formation and development of mobbing as a socio-psychological phenomenon, the stages in the structure of the mobbing process in educational groups are defined. A diagram of the relationship between objects and subjects of the mobbing process is presented. Based on the analysis, a standard version of the actions of a potential victim of mobbing has been developed. The article considers the mobbing process as a factor that negatively affects the moral and psychological climate of educational groups. The lack of a psychologically healthy climate in the educational team leads to a reluctance to work in a team and a possible decrease in the effectiveness of perception of educational material and involvement in the educational process. The authors note the need to use techniques for timely response at any stage of the mobbing process. An attempt is made to develop tools for potential victims of the mobbing process in educational groups in order to resolve a conflict situation at any stage of the process.
HIIT & RT or RT & HIIT: The order of stimulations alters acute hemodynamic response?
Authors: Oliveira-Silva Iransé , Silva Samuel Gomes , Santana Fábio
Published: April 2021

Background: The High Intensity Interval Training (HIIT) has had space in social networks that disseminate its practice and also among practitioners of physical exercises in a global way. Objective: To verify if the stimuli order (HIIT-RT or RT-HIIT) changes the acute hemodynamic response. Methods: 10 young adult male participants aged between 18 and 30 years (24.7 ± 2.2). For the test protocols the High intensity interval training (HIIT) and the conventional resistance training (RT) were performed in Cross-over using a Spinning Exercise Bike in addition to the apparatus: Bench press; Leg Press; Pull down; Leg curl; Low Rower. The hemodynamic variables were collected at rest, post-training, and 10 ', 20' and 30 'minutes of recovery. Results: A significant difference was found in HR and SBP at the end of the training in the SBP and DBP variables there were significant differences in the 20' and 30' minutes and in the MAP there was a significant difference in all recovery times with RT and HIIT higher post-workout and recovery values. Conclusion: the stimuli order changes the acute hemodynamic response. When the orders were analyzed (HIIT-RT; RT-HIIT), the order that presented the best results was HIIT-RT. It presented changes during exercise as they presented better post-training responses.
Methodology for the organisation of professional training of senior citizens: general concept
Authors: Rezer T. M.
Published: April 2021

Introduction. The process of population aging in modern civilisation is developing at an increasing pace. Russia has not remained aloof from this trend. Intense aging of the population will lead, in particular, to the fact that older people will become a necessary resource for the labour market as well as for the society activity at both macro- and micro-levels. Continuing active employment of senior citizens is a new challenge facing states.

The aim of present conceptual article is to theoretically substantiate and to develop approaches for building a model for organisation of senior citizens' professional training (persons from 50 to 70 years old). This type of training requires to be based on andragogy and geronto-gogy principles and to be targeted at continuing of labour activity by this category of population through acquisition of new professional knowledge and competencies.

Methodology and research methods. The current research is based on the methodology of system-based analysis of theoretical sources, foreign and Russian pedagogical experience. Interdisciplinary and complex approaches were used to build the concept of the model to organise professional training of senior citizens.

Results and scientific novelty. The obtained results allowed the author to conclude that at present stage of the Russian state and Russian society development, there is a need for scientific interdisciplinary knowledge, which substantiates the principles and didactic support of professional training of senior citizens in order to continue their active labour activity and to propose the concept for building the model for the organisation of such training. The conceptual model for the organisation of professional training of senior citizens is developed from the point of system-based approach and includes the following elements: 1) clarification of conceptual apparatus of senior adult education; 2) determination of anatomical and physiological features of senior citizens; 3) argumentation of the need of senior citizens for professional training; 4) determination of the peculiarities of professional training for senior citizens; 5) development of prerequisites list for successful learning of senior citizens; 6) formulation of learning objectives and tasks for its organisation; 7) choice of approaches for building the model of training and its principles as well as methodology for determining the quality and results of training.

Practical significance. The proposed concept of the model for the organisation of professional training of senior citizens can be used as a basic concept for further theoretical and practical developments in this field.
Deriva urbana como pedagogía en aulas de arte
Authors: Paz Fernández Noelia
Published: April 2021

La práctica de la deriva urbana, aunque conceptualmente nace principalmente del situacionismo, en un espectro ampliado se ha llevado a cabo a lo largo de toda la historia, pues es el acto de caminar y deambular para descubrir, es una acción inherente al ser humano. En el contexto educativo, ofrece la oportunidad de una metodología de inmersión en los espacios tanto físicos como conceptuales, sirviendo de catalizador para generar procesos, prácticas artísticas multitextuales o reflexiones en torno a los elementos que configuran dichos espacios. Es una forma de pensar la ciudad y también de ser partícipe de ella.En el presente artículo analizamos la experiencia de deriva urbana llevada a cabo en la EASD Pablo Picasso con uno de los grupos de alumnado, suponiendo una salida del centro educativo y propiciando procesos colectivos e individuales acerca del conocimiento del entorno urbano local.
Chair dimension compatibility with elementary school students anthropometric data in North Jakarta
Authors: Hiromi Hiromi , Astiarani Yunisa , Irawan Robi , Santosa Mariani
Published: April 2021

BACKGROUND In Indonesia, primary school begins at 6 years old and continues until 12, where most of their growth is experienced at that age. Non-ergonomic school furniture can harm the musculoskeletal system. This study evaluates the suitability of chair dimensions to elementary school student’s anthropometry in North Jakarta.
METHODSA cross-sectional study of 98 students in North Jakarta. Chair dimension data and student anthropometry were measured using a tape measure, which was then analyzed using the Chi-Square Goodness of Fit Test to evaluate their suitability.
RESULTSThe ages of the students ranged from 5 to 11 years. Anthropometric measurements of students show that the mean Sitting Shoulder Height is 41.81±4.36 cm, Popliteal Height 36.83±3.77 cm, Hip Breadth 25.88±3.47 cm, and Buttock-Popliteal Length 36.56±4.33 cm. While the average size assessed from the seat dimensions is Seat Height 41.71±0.22 cm, Seat Width 37.2±1.26 cm, Seat Depth 37.2±1.42 cm, and Backrest Height Above Seat 35.54±3.19 cm. The results of Goodness of Fit with Kendall's Tau-b critical value for the suitability of chair dimensions to student anthropometry were 0.37, and vice versa 0.672, which stated a discrepancy.
CONCLUSIONThere is a mismatch between chair dimension and anthropometry of elementary school students in North Jakarta. Adjustment of chair dimensions needs to be done using a student's average size approach to prevent musculoskeletal disorders.