bluuebunny/crossref_metadata_2025 huggingface dataset:
Perception of Bali cattle farmers on the performance of Extensionist based on agroecosystems at Timor Island
Authors: Marnisah Luis , Riwukore Jefirstson Richset , Habaora Fellyanus , Fuah Asnath Maria , Abdullah Luki , Priyanto Rudy , Yani Ahmad , Purwanto Bagus Priyo
Published: September 2022

This research aims to determine the perception of farmers on the performance of Extensionist in the agroecosystems of pasture, agriculture, plantation, and forest at Timor Island, so that it can be information for improving the performance of extension workers who have an impact on repair the welfare of farmers. This research was conducted from January to December 2018. The research location was determined purposively representing the agroecosystem of pasture, agriculture, plantation and forest. The determination of respondents are 5-10% of the number of farmers in each agroecosystem that has > 10 Bali cattle. Data collection methods are done through observation, interviews, and documentation. Data processing method uses a Likert Scale, then analyzed decriptivelly. Indicators to measure the performance of livestock Extensionist based on Extensionist profile, materials and methods, procurement of activities, availability of teaching aids, and intensity of extension activities. The results showed that farmers' perceptions at agroecosystems of pasture, agriculture, plantation, and forest toward livestock extensionist in the category agreed that the existence of extensionist could be said well in aspects of Extensionist profile, materials and methods, and procurement of activities. This condition explains that Extensionist in carrying out his duties and functions in the field in accordance with existing standards, namely as a mediator, motivator, educator, communicator, facilitator, and assistance/visits. Nevertheless, it is very necessary to improve and repair the role of Extensionist related to competence so that it can influence farmers to be more productive in developing Bali cattle farming business them. Then Bali cattle farmers in the pasture agroecosystem with the highest value of the use of teaching aids by extensionist were 2 kinds (44,0%). Then the average farmers in agricultural agroecosystems with the highest value of the use of teaching aids by extensionist is 1 kind (40,2%). Next, the average of farmers in plantation agroecosystems with the highest value of using teaching aids by Extensionist are > 2 kinds (47,9%). While the average farmers in forest agroecosystems with the highest value of the use of teaching aids by Extensionist is 1 kind (>77,3%). While the intensity of extension activities during the past year shows that the average farmers in agroecosystems of pasture (70,7%), agriculture (59,8%), plantations (50,0%), and forests (68,2%) said more from 1 time.
The effectiveness of cassava leaf meal (Manihot esculenta Crantz) in feed with enzymes supplementation on Broiler digestive organs
Authors: Angriani Ririn , Hermana Widya , Ridla Muhammad
Published: September 2022

This research aimed to evaluate the effect of cassava leaf meal with enzyme supplementation in feed on the digestive organs of the broiler. The research used a completely randomized factorial design on 48 Cobb-strain broilers distributed into two observation factors and four replications (consisting of 2 samples). The observation factor is factor 1 is the addition of cassava leaf meal (0%; 1.5%; and 3.0%), and the second factor is the addition of non-starch polysaccharides and protease enzymes with each dose of 250 g/ton feed (with and without enzymes). The variables analyzed were the relative weight of the digestive organs, the relative weight of the parts of the small intestine, and the relative length of the parts of the small intestine. The data obtained were analyzed by analysis of variance (ANOVA), and if the results indicated significantly different, then the posthoc test was conducted. The results showed that the addition of cassava leaf meal could increase the relative weight of the gizzard significantly (p<0.05). The addition of enzymes can significantly decrease the relative weight of the gizzard, small intestine, pancreas, ileum, and the relative length of the duodenum and ileum (p<0.05). The use of cassava leaf meal in the feed up to 3.0% does not interfere with digestive organs. There was no interaction between cassava leaf meal and enzymes on size response of digestibility broiler organ. The addition of enzymes can offset the detrimental effects caused by the use of cassava leaf meals in feed.
On the problem of impaired binding of corticosteroids to blood plasma proteins in the pathogenesis of acute radiation sickness
Authors:   Peoples' Friendship University of Russia, Omelchuk N.N.
Published: September 2022

The study of violations of the binding of corticosteroids to blood plasma proteins in acute radia-tion syndrome allows us to clarify the mechanisms and patterns of pathological changes in the hormonal level of the body in the pathogenesis of acute radiation sickness. The relevance of the study is determined by the current risks of new man-made disasters and the threat to radiation safety. The results of the study make it possible to expand a number of theoretical positions of radiobiology on the main regularities of the binding of corticosteroids to blood plasma proteins, taking into account its various fractions, which make it possible to determine the role of free corticoids in the hormonal effect in acute radiation sickness. The purpose of this work is to study the main patterns of binding of corticosteroids to blood plasma proteins in the pathogenesis of acute radiation sickness in animals. The experiments were carried out on 20 male rabbits and 475 outbred rats. Previously experimental animals were adapted to the conditions of the experiment. The total gamma-irradiation of animals was carried out on the EGO-2 unit at an average dose rate of 575 R/min. Rabbits were irradiated at a dose of 8 Gy, rats at a dose of 8,5 Gy. The total content of 11-OCS was determined by the fluorimetric method in the author's modification. The amount of free corticosteroids was determined by the difference in their content in whole plasma and in its pro-tein fraction after separation on Sephadex G-25. Results have been obtained demonstrating changes in the fractional composition of 11-OCS in blood plasma in the pathogenesis of acute radiation sickness in animals with mono- and biphasic curves of adrenocortical response to irra-diation. Disturbances in the binding of corticosteroids to blood plasma proteins were found, resulting in an increase in free, biologically active hormones in the midst of radiation sickness. The presence in the blood plasma of non-protein-bound and therefore more mobile steroids can cause a hypercorticoid state with normal or even reduced levels of hormones in the blood. The long-term effect of "hidden" hypercortisolism, therefore, may be a factor that aggravates the clinical course of acute radiation sickness.
Determinan Kontrasepsi Modern di Provinsi Maluku (Analisis Survei Demografi dan Kesehatan Indonesia Tahun 2017)
Authors: Madiuw Devita , Leutualy Vanny , Sopacua Dian Thiofany , Siahaya Griennasty Clawdya , Dasnel Muhammad Ridwan
Published: September 2022

Latar Belakang: Tren penggunaan kontrasepsi modern di Maluku menurun dalam beberapa tahun terakhir. Penggunaan kontrasepsi modern lebih rendah di perkotaan dibandingkan pedesaan.Tujuan: Mengetahui faktor penentu penggunaan kontrasepsi modern di Maluku berdasarkan hasil SDKI 2017.Metode: Desain penelitian ini adalah cross sectional dengan sumber data yaitu hasil SDKI 2017. Sebanyak 1139 data wanita usia subur menikah umur 15‒49 tahun disertakan dalam analisis. Uji bivariat menggunakan uji chi-square. Selanjutnya, dilakukan analisis mutivariat bagi variabel dengan nilai p<0,25.Hasil: Penggunaan kontrasepsi di antara wanita usia subur menikah adalah 39,9%. Umur (OR: 1,996; 95% CI: 1,471‒2,707), tingkat pendidikan (OR: 1,309; 95% CI: 1,015‒1,687) dan jumlah anak hidup (OR: 0,478; 95% CI: 0,360‒0,635) berhubungan secara signifikan dengan penggunaan kontrasepsi modern. Empat variabel lainnya tidak memiliki hubungan, yaitu daerah tempat tinggal, indeks kekayaan, sumber pelayanan KB dan kunjungan petugas.Kesimpulan: Diperlukan berbagai intervensi sebagai upaya peningkatan pengetahuan serta kesadaran wanita usia subur tentang pentingnya penggunaan metode kontrasepsi modern sebagai metode yang lebih efektif dalam mencegah kehamilan.
Point-of-Care Ultrasound Training during Nephrology Fellowship
Authors: Moore Catherine A. , Ross Daniel W. , Pivert Kurtis A. , Lang Valerie J. , Sozio Stephen M. , O’Neill W. Charles
Published: September 2022

Background and objectives

Point-of-care ultrasound (POCUS)—performed by a clinician during a patient encounter and used in patient assessment and care planning—has many potential applications in nephrology. Yet, US nephrologists have been slow to adopt POCUS, which may affect the training of nephrology fellows. This study sought to identify the current state of POCUS training and implementation in nephrology fellowships.

Design, setting, participants, & measurements

Concise survey instruments measuring attitudes toward POCUS, its current use, fellow competence, and POCUS curricula were disseminated to (1) 912 US nephrology fellows taking the 2021 Nephrology In-Training Examination and (2) 229 nephrology training program directors and associate program directors. Fisher exact, chi-squared, and Wilcoxon rank sum tests were used to compare the frequencies of responses and the average responses between fellows and training program directors/associate program directors when possible.

Results

Fellow and training program directors/associate program directors response rates were 69% and 37%, respectively. Only 38% of fellows (240 respondents) reported receiving POCUS education during their fellowship, and just 33% of those who did receive POCUS training reported feeling competent to use POCUS independently. Similarly, just 23% of training program directors/associate program directors indicated that they had a POCUS curriculum in place, although 74% of training program directors and associate program directors indicated that a program was in development or that there was interest in creating a POCUS curriculum. Most fellow and faculty respondents rated commonly covered POCUS topics—including dialysis access imaging and kidney biopsy—as “important” or “very important,” with the greatest interest in diagnostic kidney ultrasound. Guided scanning with an instructor was the highest-rated teaching strategy. The most frequently reported barrier to POCUS program development was the lack of available instructors.

Conclusions

Despite high trainee and faculty interest in POCUS, the majority of current nephrology fellows are not receiving POCUS training. Hands-on training guided by an instructor is highly valued, yet availability of adequately trained instructors remains a barrier to program development.

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2022_09_21_CJN01850222.mp3.
AN INITIAL STUDY OF IMPERATA CYLINDRICA LEAVES POTENTIAL AS HERBAL MEDICINAL INGREDIENTS
Authors: DHIANAWATY DIAH , . RUSLIN
Published: September 2022

Objective: In traditional medicines, Imperata cylindrica (hereinafter referred to as I. cylindrica) roots are more frequently used than its leaves. The aim of this study was to determine three parameters, namely the content of total phenolic compounds, total flavonoid content, and antioxidant activity of I. cylindrica leaves and roots extracts. Then, root extract parameters were used as a comparison to evaluate the benefits of I. cylindrica leaves as herbal medicine.

Methods: The total polyphenol content was measured by using the Folin-Ciocalteu method and total flavonoid content was measured by using aluminium chloride method due to measure the antioxidant activity using 1,1-diphenyl-method 2-pikrilhidrazil (DPPH) method. All methods used visible spectrophotometry.

Results: The percentages of total phenolic content, total flavonoid content, and IC50 of antioxidant activity of I. cylindrica leaves extract were 8.1 % (GAE), 2.1% (QE) and 80 ppm, respectively. Then, the measurement results of I. cylindrica roots extract showed the percentages of total phenolic content, total flavonoid content, and IC50 of antioxidant activity were 1.13% (GAE), 0.28% (QE) and 368 ppm, respectively.

Conclusion: The result showed that I. cylindrica leaves extract contained phenolic compounds and flavonoids and had antioxidant activity. The three phenolic compounds, flavonoids and antioxidant activity, have been shown to have effects on health. Therefore, the potential of I. cylindrica leaves utilization as herbal medicine can be promoted more widely.
A REVIEW ON BIOLOGICAL ACTIVITY OF 1, 3-DIAZOLE DERIVATIVES
Authors: MOHAN WAGHMARE SWEETI , B. BARVE KOMAL , K. RUCHAKE NIKITA
Published: September 2022

1,3-diazole is also known as imidazole.1, 3-diazole is amphoteric in nature i.e. it shows both acidic and basic properties 1, 3-diazole is a five-member heterocyclic aromatic compound that possesses two nitrogen, three carbon, four hydrogen atom and two double bond. It has two nitrogen atom are present; both nitrogen atom are sp2 hybridized. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. The derivatives of 1,3-diazole show different biological activities such as. Anti-inflammatory, antimicrobial, analgesic and anti-tubercular activities, etc. as reported in the literature. There are different examples of commercially available drugs in the market which contains a 1,3-diazole ring, such as Miconazole, Clotrimazole, Econazole, Enilconazole, Sulconazole etc This present review summarized some pharmacological activities and various kinds of synthetic routes for 1, 3-diazoleand their derived products.
Determination of Elastic and Mechanical Properties in CA-50 Steel by using Ultrasonic Waves
Authors: Júnior Álvaro Barbosa de Carvalho , Lopes Maria Helena Teles , Inácio Maurílio José , Ramos Samara Guedes , Rodrigues Debora Santos , Froes Gustavo Dias , Fonseca Vinícius Marques Botelho , Oliveira Jairo Andrei Vieira de
Published: September 2022

The aim of this study was to characterize the elastic and mechanical properties of CA-50 steel using the ultrasonic through-transmission technique. The electronic system used is composed of piezoelectric transducers, one emitter and another receiver of ultrasonic waves with 2 MHz frequency. Elastic properties such as Young’s modulus, shear, bulk, Poisson's ratio and anisotropy factor were estimated. In order, to estimate the mechanical properties, one mathematical model proposed in the literature was used, which related the longitudinal ultrasonic velocity with the values of tensile strength. The results obtained were compared with reference values found, attesting the feasibility of low-cost method to investigate carbon steels.
The difficulties of implementing palliative care
Authors: Araújo Mariângela Ferraz Rodrigues , Santos Ana Paula Saldanha , Amorim Andressa Jordânia Alves de , Walder Francielly Aparecida Lemos , Pisani Ivan Paioletti , Gouvea Thalyta Eduarda de Menezes , Oliveira Bruna Rafaela Gomes de Sousa , Lago Pamela Nery do , Freitas Simone Aparecida de Souza , Batista Luciana Moreira , Saturnino Danielle Cristina de Oliveira Silva , Lisboa Luciana de Morais , Fernandes Aline da Silva , Oliveira Diva Maria de , Pinto Carolina Costa , Rezende Elessandra Antônia Santos de , Menezes Nicolle Silva de , Pereira Ana Paula Caetano , Rodrigues Ronaldo Gomes , Padovani Fabíola Fontes , Costa Laiana Otto da , Silva Raquel Resende Cabral de Castro e , Ninditi Ângelo Aparecido , Pinho João Eduardo , Duarte Maria Emília Lúcio , Silva Darlan dos Santos Damásio , Golfetto Juliane Guerra , Nascimento Leticia do , Sales Rita de Cássia Almeida , Franzoi Kiwisunny Galvão , Amorim Hirlla Karla de , Fontes Kelly Monte Santo , Guimarães Rafaela Bezerra Gama , Silva Fabiana Nascimento , Fernandes Marcelo Dangllys Duarte , Silva Lisyanne Pinheiro Costa , Amorim Hilma Keylla de , Silva Tatiana Lamounier , Silva Leonardo Oliveira , Silva Michelly Angelina Lazzari da , Silva Edma Nogueira da , Cruz Ana Patrícia da , Costa Tatiana Alves , Silva Raiane Almeida , Santos Ana Luiza Loiola , Alexandre Juliana Grazielle Lobato , Costa Fernando Henrique da Silva , Bortoluzi Eugênio Barros , Andrade Maria Ivanilde de , Lazzari Daniel da Silva Costa , Alonso Claudiomiro da Silva , Silva Daniele Estéfany de Souza Pires , Quintela Andrea de Sousa
Published: September 2022

Palliative Joint Care (PC) is a set of palpable care practices that aim to prevent patients from increasing patients with diseases or a more advanced stage according to their disease. Care is provided by a multidisciplinary team, composed of nurses, nutritionists, nutritionists, doctors, whose purpose is to relieve autonomy, making what has one and the patient possible to prepare the death in their own way. The study aims to analyze the importance through qualitative data and what are the difficulties for the implementation of palliative care in the Adult Intensive Care Unit (ICU). It consists of a literature review, through a bibliographic survey, with an exploratory and relative approach, not on the physiotherapeutic performance in palliative care within the same Intensive Care (ICU) system, and how the environment among professionals is seen and graphic care multidisciplinary teams within hospitals. Realizing the importance of palliative care for critically ill patients, endorsing the phases of the patient's importance, was possible, in addition to the importance in this process. The prioritization of the patient's well-being in an intensive environment is always the focus of the treatment from the initial point, until its delivery, always maximizing its intention, psychological and physical health in a global way, where all the professionals involved are of paramount importance. with responsibility.
Cursos de pós-graduação em gestão de projetos e egressos: expectativas, lacunas e oportunidades
Authors: Possebon Cyrino José Eurico , Terribili Filho Armando
Published: September 2022

A atuação do profissional com formação superior se dá em um leque muito grande de opções. Este estudo teve por objetivo diagnosticar quanto das expectativas de egressos ou alunos avançados estão sendo preenchidas pelos programas de pós-graduação lato sensu em gestão de projetos, bem como diagnosticar quanto das expectativas do mercado de trabalho também estão sendo atendidas pelas habilidades declaradas pelos egressos dos programas em um exercício de recrutamento. O estudo foi desenvolvido na forma de levantamento de dados, por meio da aplicação de questionários estruturados, distribuídos e aplicados eletronicamente a participantes de redes sociais profissionais e consequente organização hierárquica sumarizada (“rating”) e análise qualiquantitativa dos resultados, utilizando-se da linguística cognitiva. O mercado de trabalho exige que os profissionais da área de gestão de projetos sejam proficientes em técnicas de gestão, habilidades cognitivas, psicológicas e sociais. Assim sendo, a definição dos currículos para a formação avançada dos profissionais do ramo deve ser feita de forma abrangente, aberta e versátil, adotando uma filosofia compatível com o grupo hegemônico da região, do ramo da indústria ou dos negócios privilegiado pela instituição que abriga o programa de formação.
Проточно-­инжекционное амперометрическое определение 5-гидрокситриптофана, пиридоксина и аскорбиновой кислоты, на планарном электроде, модифицированном частицами бинарной системы «золото – ​палладий»
Authors: Шайдарова Л.Г. , Челнокова И.А. , Лексина Ю.А. , Хайруллина Д.Ю. , Будников Г.К.
Published: September 2022

5-гидрокситриптофан, пиридоксин и аскорбиновая кислота являются важными биологически активными веществами, без которых невозможно оптимальное функционирование центральной нервной системы и сердечно-­сосудистой системы. Для контроля состава биологически активных добавок в клинической диагностике важно определять их содержание в реальном времени. Установлено, что частицы бинарной системы «золото – ​палладий», осажденные на планарном электроде, проявляют каталитическую активность при электроокислении 5-гидрокситриптофана, пиридоксина и аскорбиновой кислоты. Для селективного проточно-­инжекционного амперометрического определения этих соединений при совместном присутствии применяли двухканальную проточно-­инжекционную схему с параллельным расположением двух детекторов, в качестве которых выступали планарные электроды, модифицированные частицами бинарной системы «золото – ​палладий». Предлагаемый способ определения рассматриваемых органических соединений обеспечивает высокую производительность анализа.
ОБЗОР ОТЕЧЕСТВЕННЫХ ЦАП ПРОИЗВОДСТВА АО «АНГСТРЕМ»
Authors: Трудновская Е. , Клейн С.
Published: September 2022

Рассмотрен ряд новых цифро-аналоговых преобразователей производства АО «Ангстрем». Приведена информация об особенностях и характеристиках данных устройств.
НАШИ ПРИОРИТЕТЫ – ВЫСОКОЕ КАЧЕСТВО
Authors: Афанасьев А.
Published: September 2022

Многие отечественные компании,
работающие в области производства
и поставки печатных плат, в условиях
санкций пересматривают приоритеты
и сосредотачиваются на достижении
максимальной эффективности. Подходы
у всех разные: одни предприятия
расширяют производства, другие борются
за снижение конечной стоимости
продукции. Текущая ситуация заставила
компании искать оптимальные решения как
с точки зрения организации производства
и поставки готовой продукции, так
и привлечения новых клиентов и освоения
новых рынков. О месте компании
на рынке печатных плат, подходах
к организации производства, текущем
состоянии данного сектора и проблемах
российских производителей мы поговорили
с генеральным директором ООО «ГРАН Груп»
Александром Викторовичем Афанасьевым.
СКВОЗЬ САНКЦИИ К АВТОМАТИЗАЦИИ
Authors: Соболев А.
Published: September 2022

Когда спрос на продукцию растет и становится
стабильным, надо увеличивать объемы
производства, а значит – внедрять технологии
и оборудование для автоматизации. Современные
станки, роботы, множество различных
контроллеров и датчиков – всё это уже не роскошь,
а необходимость, без которой предприятиям
было бы очень непросто удовлетворять растущий
спрос на продукцию. Нетрудно догадаться, что
с приходом санкций в 2022 году, достать все
эти технологичные решения стало не только
трудно, но и дорого. Кроме того, возник риск
покупки контрафакта, а то и вовсе неполучения
заказанной продукции. Подробнее о том, как
изменилась ситуация в международной логистике
и обеспечении предприятий оборудованием
для автоматизации рассказал Александр
Соболев, генеральный директор международной
логистической компании «Транссертико».
МОЩНЫЙ ВНУТРИСОГЛАСОВАННЫЙ СВЧ-ТРАНЗИСТОР НА ОСНОВЕ GaN ДЛЯ ПЕРСПЕКТИВНОГО ТЕЛЕКОММУНИКАЦИОННОГО ОБОРУДОВАНИЯ И ДРУГИХ ПРИМЕНЕНИЙ
Authors: Бельков В. , Куршев П. , Семейкин И. , Цоцорин А.
Published: September 2022

Приводятся особенности, преимущества и эксплуатационные параметры разработанного АО «НИИЭТ» внутрисогласованного СВЧ-транзистора на основе GaN в компактном корпусе мощностью 50 Вт для работы в диапазоне частот, востребованном в передовых технологиях телекоммуникаций.
Определение химического состава чая методом ВЭЖХ
Authors: Яшин А.Я. , Яшин Я.И.
Published: September 2022

Чай известен человеку более 4 500 лет, его потребляют 2 / 3 населения мира. Чай, особенно зеленый, может помочь в защите человека от опасных болезней. Целебные свой­ства обусловлены его химическим составом, интерес, к определению которого сильно возрос в последние годы. Определение химического состава чая, в основном, проводится методом ВЭЖХ с разными детектирующими системами. Обзор таких работ приведен в настоящей статье.
Analisis Perubahan Tutupan Lahan di Kawasan Hutan Lindung Sekaroh
Authors: M. Faeshal Abdul Aziz  , Latifah Sitti , Hidayati Eni
Published: September 2022

Perubahan tutupan lahan di kawasan hutan menyebabkan perubahan struktur baik vertikal maupun horizontal. Penelitian ini bertujuan untuk mengetahui bagaimana perubahan tutupan lahan di Kawasan RTK 15 Sekaroh pada rentang waktu tahun 1990, 2000, 2013, dan 2020. Metode yang digunakan yaitu maximum likelihood classification, dimana metode tersebut mengklasifikasikan citra berdasarkan kemiripan spektrum citra dengan kondisi di lapangan. Hasil penelitian ini menunjukkan bahwa Perubahan tutupan lahan di Kawasan RTK 15 Sekaroh dari rentang waktu tahun 1990 ke tahun 2020 yaitu pada kelas tutupan hutan lahan kering primer menurun sebanyak 21,14%, kelas tutupan hutan lahan kering sekunder menurun sebanyak 16,97%, kelas tutupan semak belukar menurun sebanyak 19,53%, kelas tutupan hutan mangrove primer menurun sebanyak 2,34%, kelas tutupan hutan mangrove sekunder meningkat sebanyak 1,25%, kelas tutupan pertanian lahan kering meningkat sebanyak 30,78%, kelas tutupan pertanian lahan kering campur meningkat sebanyak 25,75%, kelas tutupan pemukiman/lahan terbangun meningkat sebanyak 4,62%, dan kelas tutupan lahan terbuka menurun sebanyak 9,08%.
Biological Evaluation of Some Novel Sulphur Substituted Chalcones as New Scaffold
Authors: Joseph Mr. Mejo , Alaxander Dr.S. , Banurekha Dr. J. , Anandkumar Dr.
Published: September 2022

In the past few decades, developing antifungal and anticancer agents has become essential in drug research. Cancer is one of the most challenging diseases in the world. Most reviews on chalcones suggested that substituted chalcones have numerous biological activities. This study aim includes synthesizing different Sulphur containing chalcones in the presence of para-amino acetophenone linked to various aldehydes in the presence of aqueous alcoholic alkali. The structural analysis of synthesized compounds was also carried out by IR, 1HNMR 13CNMR and MASS spectra. The docking study was performed by Biovia discovery studio 20202. Invitro cytotoxic activity was carried out by human breast cancer cell line MCF-7 using MTT assay. Antifungal activity was conducted by diffusion method against Candida albicans and Aspergillus niger. Novel synthesized compounds, especially BT-IV-A, BT-IV-B, BTIV- C, BT-IV-E and BT-IV-I showed significant antifungal activity as BT-IV-H, BT-IV-E, and T-IV-F revealed excellent growth-inhibitory impact for the development of new anticancer agents.
Influence of BaZnCuO3 and BaZnCuO3/rGO on the thermal decomposition of AP and NTO
Authors: Dave Pragneshkumar , sirach ruksana
Published: September 2022

BaZnCuO3 (BZC) was synthesized using the sol-gel method. The BZC was
incorporated in reduced graphene oxide (rGO) to produce BZC/rGO
composite. The synthesized catalysts were characterized using Raman,
powder X-ray diffraction (XRD), and Ultraviolet-visible (UV-Vis)
analysis. The comparative effect of BZC and BZC:rGO composite was
studied on the thermal decomposition of and
3-nitro-3H-1,2,4-triazol-5-one (NTO) and Ammonium Perchlorate (AP) using
simultaneous Thermo-gravimetric technique (TG-DTA). BZC was a better
catalyst for decreasing the thermal decomposition temperature and the
thermo-kinetic parameters of both AP and NTO compared to BZC/rGO
composite. BZC can reduce the thermal decomposition of AP and NTO by 121
oC, and 46 oC, respectively. The findings support BZC as a possible
catalyst in the thermolysis of both NTO and AP.
A Mathematical Modeling approach for Supply Chain Management under Disruption and Operational Uncertainty
Authors: Ierapetritou Marianthi , Badejo Oluwadare
Published: September 2022

In this work, we proposed a two-stage stochastic programming model for a
four-echelon supply chain problem considering possible disruptions at
the nodes (supplier and facilities) as well as the connecting
transportation modes and operational uncertainties in form of uncertain
demands. The first stage decisions are supplier choice, capacity levels
for manufacturing sites and warehouses, inventory levels, transportation
modes selection, and shipment decisions for the certain periods, and the
second stage anticipates the cost of meeting future demands subject to
the first stage decision. Comparing the solution obtained for the
two-stage stochastic model with a multi-period deterministic model shows
that the stochastic model makes a better first stage decision to hedge
against the future demand. This study demonstrates the managerial
viability of the proposed model in decision making for supply chain
network in which both disruption and operational uncertainties are
accounted for.
Identification of end stage renal disease metabolic signatures from human perspiration
Authors: Shankar Vishnu , Michael Basil , Celli Alessandra , Zhou Zhenpeng , Ashland Melanie , Tibshirani Robert , Snyder Michael , Zare Richard
Published: September 2022

End stage renal disease (ESRD), characterized by cessation in kidney
function, has been linked to severe metabolic disturbances, caused by
buildup of toxic solutes in blood. To remove these solutes, ESRD
patients undergo dialysis. As a proof of concept, we tested whether
ESRD-related metabolic signatures can be detected in perspiration
samples using a combined methodology. Our rapid methodology involves
swabbing a glass slide across the patient’s forehead, detecting the
metabolites in the imprint using desorption electrospray ionization mass
spectrometry, and identifying the key differences using machine learning
methods. Based on collecting 42 healthy and 27 ESRD samples, we find
saturated fatty acids are consistently suppressed in ESRD patients, with
little change after dialysis. Also, our method enables the detection of
uremic solutes, where we find elevated levels of uric acid (6.7 fold
higher on average) that sharply decrease after dialysis. Beyond the
study of individual metabolites, we find that a lasso model, which
selects for 8 m/z fragments from 24,602 detected analytes, achieves area
under the curve performance of 0.85 and 0.87 on training (n=52) and
validation sets (n=17) respectively. Together, these results suggest
that this methodology is promising for detecting signatures relevant for
Precision Health.
Quantitative Ergonomic Comparison of Traditional Versus Endoscopic-Assisted Tonsillectomies: A Prospective Case-Control Study
Authors: Haupt Thomas , Wadley Andrew , Hayden Jamil , Kalejaiye Adedoyin , Harley Earl
Published: September 2022

Five succinct key points: -Otolaryngologists are at high risk for
ergonomic injury, particularly in the neck and cervical spine region. -
There is a need to use validated ergonomic assessment tools to quantify
the amount of risk in specific otolaryngology procedures and identify
alternative methods to decrease that risk. -The physical positioning of
the senior author was studied using the RULA score during two different
operative approaches to tonsillectomy: one using an endoscope and one
using direct visualization without the aid of an endoscope. - The RULA
score for the traditional, non-endoscopic approach was 5, with a Neck,
Trunk, and Leg Score of 6 and a Wrist/Arm score of 1, demonstrating a
high risk and suggesting a need for further investigation and change.
The RULA score for the endoscopic-assisted approach was 3, with a Neck,
Trunk, and Leg score of 4 and a Wrist/Arm score of 1. -An
endoscopic-assisted approach to tonsillectomy allowed for a lower RULA
score than traditional tonsillectomy. This study suggests that an
endoscopic approach may decrease the potential for musculoskeletal
strain and reduce occupational-related pain and injury seen in
practicing otolaryngologists.
Influence of Matrix Metalloproteinases content on eardrum atrophy in Otitis Media with Effusion in children
Authors: Casteil Lylou , Affortit Corentin , Puel Jean Luc , Blanc Fabian , Venail Frederic , Wang Jing , Mondain Michel
Published: September 2022

Objectives Otitis media with effusion (OME) is a common pathology in
children. Effusions contain Metalloproteinases (MMPs), which can lead to
atrophy of the tympanic membrane (TM) due to destructive effect on the
lamina propria. Not all cases of OME are complicated with atrophy, maybe
explained by an inter-individual variation of MMP concentration in
effusions. The purpose of this study was to determine the correlation
between concentration of MMPs and existence of TM atrophy in children.
Participants - Main outcome measures The effusion from thirty middle
ears were collected during insertion of VT in children aged 15 months to
10 years, including 11 eardrums with tympanic atrophy and 19 without
tympanic atrophy. ELISA tests were used to measure concentrations of
MMP-2, MMP-7, MMP-9 and TIMP-2 in the effusions. Correlations between
MMP levels and atrophy of eardrum was investigated, as well as
correlation with age, gender, number of previous ventilation tube
insertion, and viscosity of the glue. Results The mean concentration of
MMP-2 was higher in the atrophic group than in effusions without TM
atrophy (0.6 ng/mg versus 0.5 ng/mg total protein respectively), while
the TIMP-2 concentration was lower in this group. The level of MMP-2
decreased with the age. Finally, a significantly higher concentration of
MMP-9 and TIMP-2 was found in high-viscosity effusions. Conclusion This
study suggests that MMP-2 activity could play an important role in
destruction of the eardrum during OME in infancy. MMP-2 level assessment
could be interesting for determining children with risk of lamina
propria destruction.
Hypersensitivity pneumonitis associated with the yeasts Trichosporon asahii and Candida parapsilosis and with humidifier fever.
Authors: Soumare Dianguina , Kanoute Tenin , Cassagnes Lucie , Laurichesse Guillaume , Muti Daniela , Caillaud Denis
Published: September 2022

Here, we present the first case of hypersensitivity pneumonitis to
Yeasts (Trichosporon asahii and Candida parapsilosis) and associated
with humidifier fever linked to exposure to gram negative bacteria and
endotoxins. The association of HP and humidifier fever is rarely
reported.
Acral Hemorrhagic Darier’s Disease with Spontaneous Regression over time: A Case Report
Authors: Rassafian Marzie
Published: September 2022

we reported a-24-year-old woman, who was a known case of Darier Disease
(DD) since the age of 5 years old. She was presented with hemorrhagic
macules, and vesicles on the dorsum aspects of her hands, fingers, and
palmar area with no triggers like trauma, and with spontaneous recovery.
Analyses of solutions of Riemann-Liouville fractional oscillatory differential equations with pure delay
Authors: Fan Zhenbin , Pan Renjie
Published: September 2022

This paper firstly finishes off the exact solutions of Riemann-Liouville
fractional differential time-delay oscillatory system of order
ρ∈(1 ,2) by using two newly defined delayed perturbations
of Mittag-Leffler matrix functions and constant variation method. In the
light of the exact solutions, we explore the finite time stability of
the nonhomogeneous fractional oscillatory differential equations with
pure delay. Ultimately, an example is cited to verify the rationality of
the results. Through our method, the public problems left by Mahmudov in
2022 were partially solved.
Effectiveness and tolerability of Perindopril plus Amlodipine single pill combination in Nigeria: The 13 City Hypertension Study
Authors: Ojji Dike , Ansa Victor , Ale Boni , Sani Mahmoud , Obasahan Austine , Alagbe Sola , Williams Rotimi , Aknitomide Tony , Okoye Innocent , Umuerri Ejiroghene , Nwafor Eze , Mbakwem Amam , Amadi Casmir , Shedu Lamkur , Familoni Ranti , Olunuga Taiwo , Inofomoh Francisca , Osuji Ukachukwu , Omejua Godwin , Azubuike Benjamin , Ohihoin Esther , Anakwe Raphael
Published: September 2022

Background: There is no large-scale study that has shown the efficacy of single pill combination (SPC) antihypertensive medications in black African population. We therefore evaluated the blood pressure (BP) lowering efficacy and the tolerability of Perindopril plus Amlodipine SPC in black African patients. Methods: It was a multi-centre, prospective, observational programme among hypertensive patients using different doses of Perindopril and Amlodipine. Primary endpoint was assessed as the change in mean sitting systolic and diastolic BPs from baseline to 3 months. Results: 937 patients (55.7% female) were analysed, and the mean age was 56.4 ± 12.7 years. Systolic and diastolic BPs were significantly reduced by 17.3/ 9.4mmHg, 21.1/10.8mmHg mmHg and 24.6/12.7mmHg at 4, 8 and 12 weeks respectively compared to baseline value (p<0.0001). Dry cough was seen in 0.64% and angioedema 0.1% of the patients. Conclusions: Perindopril plus Amlodipine SPC provided clinically meaningful BP reductions and is well tolerated in a black African population.
Zoonotic Endocarditis: Is the feather mightier than the sword?
Authors: Esmail A , Doubell A F , Piek H , Janson J T , Pecoraro A J K
Published: September 2022

The common causes of infective endocarditis (IE) in South Africa are Staphylococcus aureus, the viridans streptococci and Bartonella species. Infection with Erysipelothrix rhusiopathiae is a rare cause of IE that is usually associated with occupational exposure and can be acquired from humans and animals. It was fi rst reported in 1912 by Gunthar, and thereafter fewer than 60 cases have been reported. We describe a case of Erysipelothrix rhusiopathiae induced endocarditis in Cape Town, South Africa. S
Pengembangan Media Film Pendek “ASA” sebagai Upaya Pencegahan Kekerasan Seksual di Sekolah Menengah Atas
Authors: Aminah Siti , Setiawan Antonius Ian Bayu
Published: September 2022

ABSTRACT This study aims to develop the Short Movie “ASA” for media for guidance and counseling services to prevent sexual violence in high school. This research uses a Research and Development procedure. Based on the material expert’s assessment, the media obtained  94,4% with a decent category. Moreover, the media expert’s assessment showed 87,5 with a decent category. The result of the user test assessment is 92,27% in the decent category. In conclusion, the short movie “ASA” is decent for media guidance and counseling services to prevent sexual violence in high school.  ABSTRACT This study is guidance counselling action research (PTBK) which was done in SMP Negeri 1 Paciran. Focus of this research is solving students’ lateness to school which was found in SMP Negeri 1 Paciran. The subject of this research is five students who came late. They got group counselling service to solve their problem. In addition, PTBK in this study contained two cycles which was done for eight weeks. The result of this PTBK shows that group counselling treatment can be used to solve students’ lateness to school. Keywords: group counselling service, lateness, PTBK
Edição semidiplomática da Caderneta de estudos e exercícios de latim-português e português-latim de Carlota Joaquina
Authors: Ribeiro da Silva Marcelle Mayne
Published: September 2022

Este trabalho apresenta uma edição semidiplomática da Caderneta de Estudos e Exercícios de Latim-Português e Português-Latim de Carlota Joaquina, que está sob guarda do Arquivo Nacional do Rio de Janeiro. De autoria de Sebastião Rodrigo Costa, professor do Real Colégio dos Nobres, serviu de subsídio para o aprendizado de Língua Latina da Infanta Carlota Joaquina, infanta de Espanha que, com dez anos de idade, mudou-se para Portugal para se casar com D. João, filho de D. Maria I e D. Pedro III. Acreditamos que nossa edição contribuirá para os estudos de pesquisadores que se interessam pela transmissão da Língua Latina no século XVIII ou pela educação da nobreza da Europa nesse século.
“Biblioteca Universal”: saberes necessários para a boa educação segundo monges da Ordem de Cister
Authors: Bretas Davi
Published: September 2022

O livro Biblioteca Universal: em a qul se contem huã util, e muy proveytosa de todas as maes principaes noticias, de 1727, é um trabalho apógrafo, copiado por monges da Ordem de Cister, do Mosteiro de Santa Maria, em Alcoçaba. Disponibilizado digitalmente pela Biblioteca Nacional de Portugal, a obra apresenta ensinamentos variados, que tangem desde curiosidades e estudos referentes às ciências da natureza a discussões sobre a ética e a moral com base nas crenças da fé cristã. Dividido em sete tratados, o texto transcrito no presente trabalho aborda as páginas iniciais do livro. Sendo assim, inclui tanto informações de contracapa quanto um prólogo, além de dois fólios referentes ao primeiro tratado, no qual o autor dedica-se a transcrever ensinamentos de cunho religioso para um viver social considerado adequado e proveitoso.
A solfa do Romance da Bela Infanta: uma melodia italiana do século XVII teria sobrevivido na tradição oral brasileira?
Authors: Issa Gonçalves Daniel
Published: September 2022

O artigo avalia a hipótese de que o Ballo di Mantova, melodia italiana cuja versão mais antiga registrada data do início do século XVII, possa ter influenciado a música brasileira de tradição oral. Segundo Luigi Ferdinando Tagliavini, essa "melodia errante" se difundiu por toda a Europa ainda no seiscentismo na forma de música vocal profana, hinos religiosos, danças, peças para teclado ou tablaturas para alaúde e guitarra. Foi utilizada por compositores eruditos nos séculos XVIII e XIX como Mozart e Smetana, e é encontrada "ainda em vida" nos dias de hoje no folclore do norte da Itália. No entanto, esse motivo musical também está presente em algumas peças do folclore brasileiro, recolhidas na Paraíba, Bahia, São Paulo, Rio de Janeiro e Minas Gerais por Guilherme de Mello, Ariano Suassuna e Rossini Tavares de Lima.
“Santa Cecília ressurge” – considerações preliminares sobre a atividade musical do Seminário de Mariana na primeira metade do século XX
Authors: Godinho Josineia
Published: September 2022

Este trabalho tem por objetivo trazer à luz a trajetória da atividade musical dentro do Seminário de Mariana. Em 2020 a instituição celebrou seus 270 anos de fundação e estabeleceu-se na história como uma das mais tradicionais e prestigiadas casas de formação para sacerdotes no país. Egressos do Seminário ocuparam cargos de destaque tanto na vida religiosa quanto secular e política não só em Minas Gerais, mas em todo o Brasil. Para melhor entender o desenvolvimento das atividades musicais dentro do Seminário, abordamos inicialmente a história da instituição desde a sua fundação ainda no século XVIII, continuando com uma análise do perfil dos alunos e do currículo oferecido até que a Música passasse de fato a fazer parte da formação musical dos futuros sacerdotes. A vida musical do Seminário até a década de 60 do século XX foi retratada através de relatos escritos, acervos e entrevistas, que corroboram a importância da vivência artística no processo de formação dos futuros líderes religiosos.
Análise da religião em suas formas e suas perspectivas diversas
Authors: Gonçalves Paulo Sérgio Lopes , Fernandes Márcio Luiz
Published: September 2022

Neste texto, o objetivo é apresentar a configuração geral desse dossiê intitulado “Análise da religião em suas formas e suas perspectivas diversas”. Esse objetivo é justificado em duas dimensões: a conceitual e a analítica. Na primeira, a concepção de “religião” é marcada pela pluralidade epistêmica e fenomenológica, pois não há univocidade conceitual e há formas diversas de manifestação do fenômeno religioso. Nesse sentido, a diversidade de concepções propicia que a religião seja concebida nas instituições religiosas, nas relações interpessoais, em manifestações de devoção popular, na esfera privada do sujeito, nas obras artísticas diversas – pintura, literatura, cinema, esculturas – e nas relações com a política e a sociedade. Na segunda, desde o século XIX, a religião saiu da exclusiva esfera analítica da teologia e da filosofia – principalmente em sua condição de teodiceia – e se tornou objeto de investigação da filosofia hermenêutica e fenomenológica, da história, da sociologia, da antropologia, da psicologia, do direito, das teorias da literatura e da ciência da religião enquanto concebida como disciplina, das ciências da linguagem e da comunicação. Por meio dessas ciências o fato-fenômeno religioso pôde ser circunscrito, definido e, por sua vez, descrito por meio de um método de aproximação científica. Essa diversidade de perspectivas de análise implica ter uma referência científica para conceituar a religião epistemologicamente e para analisar as suas manifestações, tanto em seus ritos e narrativas, quanto em seus mitos, configurações grupais, símbolos e objetos propriamente religiosos. No entanto, essa diversidade não implica que a análise deva fechar-se em sua respectiva ciência; ao contrário, a própria análise remete ao diálogo epistêmico que produz a interdisciplinaridade e, também, a transdisciplinaridade, concebidas como formas denotativas nas quais as ciências se encontram e auxiliam umas às outras em suas respectivas configurações epistemológicas em suas análises. É nesse espírito interdisciplinar que se encontra a área das Ciências da Religião, propiciando que as ciências se referenciem na religião e na sua dinâmica analítica, se encontrem, efetivem o diálogo epistêmico e desenvolvam o seu escopo científico.
QUALITY MANAGEMENT OF LEARNING AS AN EFFORT TO INCREASE SCHOOL ACCREDITATION VALUE DURING THE PANDEMIC
Authors: Fakhrurrozi Hatta , Hamdani Fikri
Published: September 2022

This research was inspired by the phenomenon of the COVID-19 pandemic and the continuity of learning in remote schools, which was related to an increase in school accreditation. This type of research is qualitative and uses a naturalistic approach. This multi-site research examines two schools, SMPN 3 Satap Banawa Tengah and SMPN 11 Satap Palolo. The focus of this research is to find out the practice of quality management of education in both schools to answer the research questions as: 1) management of the learning process during a pandemic; 2) correlation of learning process management with school accreditation. Research data was collected using structured interviews, observation, and documentation. The data was analyzed using data reduction, presentation, and triangulation. This study found that quality management of the learning process was consistently carried out at the school during the pandemic. Both schools have implemented limited semi-online learning. Limited semi-online learning has similarities with other online learning but also has differences in implementation aspects. The second finding, every step taken by the principal in managing the learning process, refers to the accreditation guidelines that the ministry of education and culture has set. The analysis is carried out by critiquing each question item in the accreditation guidelines and is adjusted to the steps taken by the school. In practice, it's hard for schools to meet some of the accreditation requirements. However, in terms of the formal parts of the learning process, every step schools have taken has met the criteria set by the ministry of education.
Llegar a ser uno mismo
Authors: Carpintero Acero Raquel
Published: September 2022

El pensamiento de Kierkegaard impide de suyo el acercamiento a la realidad del ser humano desde una actitud meramente especulativa; puesto que el hombre es espíritu, la libertad está siempre presente, haciendo inadecuado cualquier acercamiento que ignore dicha condición. El ser humano no es una realidad estática, y por ello, para comprender su dinamismo propio, es necesario adentrarse en la aparente contradicción de ser misterio y tarea para sí mismo. El presente artículo seguirá esa misma dirección, a partir de las descripciones recogidas en El concepto de angustia y La enfermedad mortal.