bluuebunny/crossref_metadata_2025 huggingface dataset:
Continuation and limit properties for solutions of strongly nonlinear second order differential equations
Authors: Pucci Patrizia , Serrin James
Published: November 2019

This paper deals with continuation, boundedness and asymptotic behavior of solutions of second order ordinary differential equations of variational type. The equations considered are nonlinear both in the solution variable and in its derivative. For equations arising from the degenerate Laplace operator, precise asymptotic behavior is established, along with various monotonicity and oscillation properties. Similar results are obtained also for other classes of nonlinear second order differential operators. The results of the paper also include generalizations of theorems of Fowler, Levin and Nohel, and Artstein and Infante. The main tool of the paper is a variational identity which supplies a useful new family of Liapunov functions for nonlinear equations.
Stabilisation de l'équation des ondes au moyen d'un feedback portant sur la condition aux limites de Dirichlet
Authors: Bardos Claude , Halpern Laurence , Lebeau Gilles , Rauch Jeffrey , Zuazua Enrique
Published: November 2019

On étudie l'équation des ondes y″−Δy=0 dans Ω×(0,∞) (Ω est un domaine borné et régulier de Rn) avec les conditions aux limites dissipatives y=(∂/∂v)(Gy′) sur ∂Ω×(0,∞), où G=(−Δ)−1:H−1(Ω)→H01(Ω), et des donnees initiales dans L2(Ω)×H−1(Ω). On démontre, par des méthodes de l'analyse microlocale, que toute solution {y(t),y′(t)} converge vers zéro exponentiellement dans L2(Ω)×H−1(Ω) lorsque t→+∞. On démontre en fait la stabilisation pour toute une classe de conditions aux limites qui contient celles ci-dessus et les conditions aux limites classiques y′+∂y/∂v=0. On étudie finalement, par les mêmes méthodes, les conditions aux limites absorbantes.
Homogenization of strongly nonlinear equations with gradient dependent lower order nonlinearity
Authors: Boccardo L. , Del Vecchio T.
Published: November 2019

This paper deals with the G-convergence of some quasi-linear elliptic equations, when the lower order term has sub-quadratic growth with respect to the gradient.
On the zeros of Bessel type functions and applications to exact controllability problems
Authors: Komornik Vilmos
Published: November 2019

We derive several new monotonicity properties and asymptotical formulae for the positive zeros of various Bessel type functions. Using these results we characterize the exactly controllable states for some circular plate models. We show that they are independent of the control time.
Correctors for the homogenization of conservation laws with oscillatory forcing terms
Authors: E Weinan , Serre Denis
Published: November 2019

We prove a corrector type result for the homogenization of scalar conservation laws with oscillatory forcing terms. The proof makes use of the concept of two-scale Young measure which is a generalization of the classical Young measure.
Homogenization of nonstationary flow of a two-constituant mixture through a porous medium
Authors: Aganović I. , Mikelić A.
Published: November 2019

The homogenization of nonstationary flow of a general two-constituant mixture in a domain with a grained boundary (porous medium) is considered. A convergence theorem for the homogenization process, together with a uniqueness theorem for a homogenized problem, is proved. The homogenized system turns out to be the widely used engineering model of miscible flow through a porous medium.
“More boundary energy dissipation” does not necessarily imply larger asymptotic decay rates
Authors: Chen Goong , Huang Falun , Lin Chin-Yuan
Published: November 2019

For the wave equation with an impedance boundary condition in a bounded domain, it is known that its energy will decay uniformly exponentially provided that the domain has, e.g., a star-shaped geometry (Chen, 1979; Lagnese, 1983). So it appears natural at first sight that the energy decay rates should increase when there is additional energy dissipation on the boundary contributed by higher-order tangential derivatives. In this paper, we study the evolution of the wave equation with such higher-order tangential dissipative boundary conditions. By using a geometrical optics expansion and a wave method argument, we show by an example on a 2-dimensional disk that at high frequencies the highest-order derivative in the boundary condition is dominant, and there is no uniform exponential decay for such modes. This constitutes a counterexample to the seemingly natural “comparison theorem” for energy decay properties.
Resolution of the critical cases for problems with L1-data
Authors: Rakotoson Jean Michel
Published: November 2019

We introduce a new type of sets for problems with L1-data associated with the standard Leray-Lions operator. The solutions cannot be found in the usual Sobolev spaces.
Turning points and phase shifts in ordinary differential equations with saturating nonlinearity
Authors: Karasev M.V. , Pereskokov A.V.
Published: November 2019

In this paper we consider an ordinary differential equation with nonlinearity which becomes constant if the solution amplitude increases. We use a modification of the Kuzmak–Whitham method, solutions of boundary layer type and a model Painleve equation. We constructed a global asymptotic solution including neighbourhoods of turning points and calculated the phase shifts at turning points taking into account the nonlinear character of corrections. An asymptotics of eigenvalues is found.
Upper bounds on the number of scattering poles and the Lax–Phillips conjecture
Authors: Petkov Vesselin , Vodev Georgi
Published: November 2019

We obtain a new type of upper bounds on the number of scattering poles which allow to give some sufficent conditions for the Lax-Phillips conjecture (and also the modified one) to hold for a class of compactly supported hypoelliptic perturbations of the Laplace operator in Rn, n≥3 being odd.
A Riemann problem whose viscosity solutions contain δ-measures
Authors: Joseph K.T.
Published: November 2019

In this paper we study the Riemann problem for a 2×2 system of conservation laws, whose solution need not be real-valued functions, but may contain δ-measures concentrated along some curves. We consider a parabolic approximation of the Riemann problem and obtain an explicit formula. Then the solution of the Riemann problem is obtained as the limit of this approximate solution.
Travelling waves in shallow water revisited
Authors: Frank L.S.
Published: November 2019

Quasi-stationary surface water waves propagating along a distinguished space direction in an infinite channel of finite depth are considered under the assumption that the liquid is inviscid and incompressible. Besides the gravitation effect also the capillary phenomenon is taken into consideration. After rescaling the mathematical problem is reduced to a singularly perturbed pseudodifferential equation on the free boundary of the liquid. Depending on the values of two basic dimensionless parameters, the rescaled speed of propagation and the parameter characterizing the surface tension (capillarity), the existence of different kind of quasi-stationary waves (periodic, quasi-periodic and solitary) is established for this exact mathematical model and their asymptotic behavior is investigated when the natural dimensionless small parameter (the ratio of the depth of the undisturbed liquid's layer and the wave's length scale) vanishes.
Asymptotic expansion of singular operators on Sobolev spaces
Authors: Penzel F. , Speck F.-O.
Published: November 2019

The topic of asymptotic expansion of solutions of pseudodifferential equations in the spirit of Eskin's work is extended to a more general situation. Taylor expansion of Fourier symbol matrix functions is replaced by a series of generalized invertible operators, which act on vector Sobolev spaces. The fractional orders of these spaces are obtained from the jumps of the lifted symbol matrix at infinity in a situation which is most interesting for applications. Asymptotic and regularity results for the solutions of corresponding systems of equations are direct consequences.
A justification of a non-linear model of spherical shell
Authors: Rao Bopeng
Published: November 2019

We consider a non-linear model of elastic spherical shell subjected to suitable hydrostatic pressure. Applying the method of asymptotic expansions to the general three-dimensional equilibrium equations, it is shown that the leading term of the expansions is a solution of a known two-dimensional model in non-linear shell theory.
Stability of resonances under smooth perturbations of the boundary
Authors: Stefanov P.D.
Published: November 2019

We prove that the resonances related to a second order elliptic differential operator with Dirichlet boundary conditions are stable in each compact of the complex plane under small C2-perturbations of the boundary and small changes of the coefficients.
Asymptotic analysis of reaction-diffusion-electromigration systems
Authors: Henry J. , Louro B.
Published: November 2019

We consider a Nernst-Planck-Poisson system modelling ion migration through biological membranes, in the one dimensional case. The model includes both the effects of biochemical reaction between ions and of fixed charges. We state the existence of solutions under either an imposed potential condition or an imposed current condition. We study the asymptotical behaviour of solutions in the limit of electroneutrality. Non-uniform convergence gives rise to jump in the potential, known as Donnan potential. Finally we give correctors which describe the charged boundary layers.
Polynomial bounds on the number of resonances for some complete spaces of constant negative curvature near infinity
Authors: Guillopé Laurent , Zworski Maciej
Published: November 2019

Let X be a conformally compact n-dimensional manifold with constant negative curvature −1 near infinity. The resolvent (Δ−s(n−1−s))−1, Res>n−1, of the Laplacian on X extends to a meromorphic family of operators on C and its poles are called resonances or scattering poles. If NX(r) is the number of resonances in a disc of radius r we prove the following upper bound: NX(r)≤Crn+1+C.
Classification analytique de champs de vecteurs 1-résonnants de (Cn,0)
Authors: Stolovitch Laurent
Published: November 2019

Nous étudions les champs de vecteurs analytiques X de (Cn,0) à partie linéaire diagonale non-nulle et dont les valeurs propres λi satisfont d'une part à des relations de résonnance toutes engendrées par une seule relation r1λ1+…+rnλn=0 avec des ri∈N non tous nuls, et d'autre part à une condition de petits diviseurs diophantiens. Nous montrons que lorsque x1r1…xnrn n'est pas une intégrale première d'une forme normale de X, alors X admet une forme normale polynômiale. Si cette dernière vérifie certaines hypothèses, nous obtenons une classification analytique des champs formellement équivalents à cette forme normale. Dans le cas particulier de la dimension 2, nous retrouverons les classifications de Martinet-Ramis sans distinguer le cas d'une valeur propre nulle du cas où le rapport des valeurs propres est un rationnel négatif.
Travelling wave solutions to a condensed phase combustion model
Authors: Logak Elisabeth , Loubeau Vincent
Published: November 2019

A one-dimensional model for flame propagation in condensed phase combustion is considered. We prove existence and uniqueness of travelling wave solutions for finite activation energy. We study the asymptotic limit of the model for high activation energy.
Calculation of a Stokes multiplier
Authors: Sibuya Yasutaka , Tabara Tatsuhiko J.
Published: November 2019

We will show how to calculate a Stokes multiplier concerning subdominant solutions of a second-order differential equation with polynomial coefficients without utilizing any suitable integral representation of its solutions. This equation is reducible to a biconfluent Huen equation. We use results of isomonodromic deformation of the differential equation.
Asymptotics of arbitrary order for a thin elastic clamped plate, I. Optimal error estimates
Authors: Dauge Monique , Gruais Isabelle
Published: November 2019

This paper is the first of a series of two, where we study the asymptotics of the displacement in a thin clamped plate made of a rigid “monoclinic” material, as the thickness of the plate tends to 0. The combination of a polynomial Ansatz (outer expansion) and of a boundary layer Ansatz (inner expansion) yields a complete multi-scale asymptotics of the displacement and leads to optimal error estimates in energy norm. We investigate the polynomial Ansatz in Part I, and the boundary layer Ansatz in Part II.

If ε denotes the small parameter in the geometry, we first construct the algorithm for an infinite “even” Ansatz involving only even powers of ε, which is a natural extension of the usual Kirchhoff-Love Ansatz. The boundary conditions of the clamped plate being only satisfied at the order 0, we try to compensate for them by boundary layer terms: we rely on a result proved in Part II giving necessary and sufficient conditions for the exponential decay of such terms. In order to fulfill these conditions, the constructive algorithm for the boundary layer terms has to be combined with an “odd” polynomial Ansatz. The outcome is a two-scale asymptotics involving all nonnegative powers of ε, the in-plane space variables xα, the transverse scaled variable x3 and the quickly varying variable r/ε where r is the distance to the clamped part of the boundary.
Homogenization for thermoconductivity in a porous medium with periods of different orders in the different directions
Authors: Bakhvalov N.S. , Saint Jean Paulin J.
Published: November 2019

We study here the problem of heat transfer in a porous medium consisting of a homogeneous isotropic material. We assume that the period of the medium is not the same in the two directions and that the ratio of these two periods tends to zero. We find the explicit representation of the coefficients of the averaged equations and prove strong convergence to the solution of the averaged problem.
Two-term asymptotics for the sum of eigenvalues of the Schrödinger operator with Coulomb singularities in a homogeneous magnetic field
Authors: Sobolev Alexander V.
Published: November 2019

We study the sum of negative eigenvalues M(h,μ) of the Schrödinger operator HV(h,μ) in L2(R3) with a decaying at infinity potential V and a homogeneous magnetic field of intensity μ. The parameter h denotes the Planck constant. Assuming that V has a finite number of Coulomb singularities and is smooth outside them, we establish the two-term asymptotics of M(h,μ) as h→0 and μ→∞. The second term is determined only by the singularities of V and it turns out to be the same as in the case μ=0.
Asymptotic behavior of solutions to Maxwell's system in bounded domains with absorbing Silver–Müller's condition on the exterior boundary
Authors: Barucq H. , Hanouzet B.
Published: November 2019

We develop an asymptotic study of Maxwell's system involving an absorbing boundary condition. First- and second-order systems are considered. In both cases, we prove that the solution converges towards a steady state depending on the geometrical properties of the obstacle. The asymptotic state involves the data of the problem.
Homogenization of biharmonic equations in domains perforated with tiny holes
Authors: Huang Chaocheng
Published: November 2019

This paper deals with the homogenization of the biharmonic equation Δ2u=f in a domain containing randomly distributed tiny holes, with the Dirichlet boundary conditions. The size σ of the holes is assumed to be much smaller compared to the average distance ε between any two adjacent holes. We prove that as ε,σ→0, the solutions of the biharmonic equation converge to the solution of Δ2u+κu=f, where κ depends on the shape of the holes and relative order of σ with respect to ε.
PENGARUH STRATEGI PERIKLANAN TERHADAP KEPUTUSAN MAHASISWA(Studi Kasus Pada STIKes Pertamina Bina Medika Jakarta)
Authors: Kasmad Kasmad , Ahidin Udin Ahidin , Wijayanti Kiki Dwi
Published: November 2019

ABSTRAK                                         Penelitian ini bertujuan untuk mengetahui Pengaruh Strategi Periklanan terhadap keputusan mahasiswa pada Sekolah Tinggi Ilmu Kesehatan Pertamina Bina Medika (STIKes Pertamedika) Jakarta.Penelitian ini bersifat deskriptif asosiatif, Populasi dalam penelitian ini adalah mahasiswa program studi S1 dan D III keperawatan Semester 1 yang berjumlah 140 orang dengan teknik sampling secara acak Stratified Random Sampling yaitu dengan cara mengambil sample dengan memperhatikan strata (tingkatan) di dalam populasi serta menggunakan table Isaac dan Michael dalam menentukan sampel. Adapun sampel dalam penelitian sebanyak 100 orang. Pengumpulan data dengan menggunakan kuesioner data yang diperoleh dari kuesioner kemudian dianalisis menggunakan bantuan program Microsoft Excel dengan metode uji validitas, uji reliabilitas, koefisiensi korelasi, koefisiensi determinasi, dan uji hipotesis.Terdapat pengaruh positif dan signifikan antara strategi periklanan (X) terhadap keputusan mahasiswa (Y) dengan nilai koefisiensi korelasi ( r ) = 0.858. besarnya pengaruh atau kontribusi strategi periklanan (X) terhadap keputusan mahasiswa (Y) sebesar 73,62%. Tingkat signifikansinya adalah signifikan t hitung 9,2326 > t tabel 1,984, maka H0 ditolak dan H1 diterima, dengan demikian hipotesis dalam penelitian ini adalah terdapat pengaruh positif dan signifikan antara strategi periklanan (X) terhadap keputusan mahasiswa (Y) di STIKes Pertamina Bina Medika Jakarta.Kata Kunci : Strategi Periklanan, Keputusan Mahasiswa
PENERAPAN PROMOSI DAN STRATEGI PEMASARAN TERHADAP PERKEMBANGAN USAHA (PT JM MUTU UTAMA SERPONG)
Authors: Mustakim Masran
Published: November 2019

ABSTRAK Strategi pemasaran merupakan cara yang sangat penting untuk diterapkan oleh perusahaan jasa maupun non jasa agar dapat bersaing di pasar. Penelitian ini bertujuan : (1) Untuk mengetahui strategi pemasaran yang digunakan oleh PT JM Mutu Utama dalam meningkatkan volume penjualan. (2) Untuk menganalisa strategi pemasaran yang seharusnya dilakukan oleh PT JM Mutu Utama yang sesuai dengan kondisi perusahaan saat ini.Penelitian ini dilakukan di PT JM Mutu Utama dengan menggunakan metode penelitian deskriptif dengan melakukan observasi. Metode pengumpulan data yang digunakan adalah metode penelitian lapangan dan kepustakaan. Untuk menganalisis data dari lapangan, digunakan metode deskriptif dengan menggunakan analisis SWOT (Streght, Weakness, Opportunity, Threat).Hasil penelitian menunjukan bahwa (1) Strategi penerapan prromosi yang dilakukan oleh PT JM Mutu Utama mampu meningkatkan pertumbuhan volume penjualan. (2) Melalui analisa EFAS (External Strategic Factor Analysis Summary) diperoleh skor total 2,70 dan melalui analisa IFAS (Internal Strategic Factor Analysis Summary) diperoleh skor total 3,45. Sehingga nilai tersebut dimasukan pada analisa SWOT yang menunjukan posisi PT JM Mutu Utama berada pada kuadran I, sehingga strategi pemasaran yang cocok dilakukan oleh PT JM Mutu Utama adalah Strategi Agresif atau perluasan untuk memaksimalkan kekuatan internal dan eksternal perusahaan dengan melakukan pengembangan pasar, pengembagan produk, dan inovasi.Saran yang diberikan peneliti kepada PT JM Mutu Utama adalah dengan mengetahui hasil dari penelitian strategi pemasaran perusahan maka diharapkan agar PT JM Mutu Utama lebih memperhatikan sumber daya manusia, anggaran promosi, dan menjalin kemitraan dengan perusahaan lain. Kata Kunci : Strategi Pemasaran
MENUMBUHKAN INTENSI BERWIRAUSAHA PADA MAHASISWA MANAJEMEN UNIVERSITAS PAMULANG
Authors: Rahayu Krida Puji
Published: November 2019

ABSTRAK Penelitian ini bertujuan untuk mengetahui karakteristik kewirausahaan mahasiswa Universitas Pamulang (UNPAM) dan faktor-faktor yang mempengaruhi intensi kewirausahaan mahasiswa UNPAM. Intensi berwirausaha adalah kepedulian atau ketertarikan seseorang terhadap hal-hal kewirausahaan. Dengan adanya pendidikan kewirausahaan diharapkan mahasiswa memiliki jiwa wirausaha serta wadah bagi mahasiswa untuk berwirausaha. Pendidikan kewirausahaan digunakan untuk menumbuhkan jiwa wirausaha dan memberikan bekal pengetahuan kepada mahasiswa supaya dapat menciptakan lapangan pekerjaan setelah lulus nanti. Kata Kunci : menumbuhkan minat, Intensi Berwirausaha.
Cytotoxic activity of zinc oxide/titanium dioxide nanoparticles on prostate cancer cells
Authors: TAS Ayca , KEKLİKCİOGLU CAKMAK Nese , AGBEKTAS Tugba , SİLİG Yavuz
Published: November 2019

Prostate cancer is caused by uncontrolled growth of cells in the prostate gland. The aim of this study was to determine the cytotoxic activity of titanium dioxide (TiO2) and zinc oxide (ZnO) nanoparticles (NPs) and TiO2 + ZnO nanocomposite (NC) in human prostate cancer cell line (DU-145) and healthy mouse fibroblast cell line (L-929). In the study, TiO2 and ZnO NPs and TiO2 + ZnO NC were synthesized. Cytotoxic activities of NC and NPs was then analyzed in human prostate cancer cell line (DU-145) and healthy mouse fibroblast cell lines (L-929) using the MTT method. TiO2, ZnO and TiO2 + ZnO IC50 values were determined in DU-145 and L-929 cell cells (n = 6). TiO2 + ZnO NC in the Du-145 cell line was found as the most active, having statistically significant (***p < 0.0001, **p ˂ 0.001 and **p ˂ 0.01).
近年来水污染处理领域中对铜离子吸附的新进展
Authors: 吴 玉婷
Published: November 2019

水源水中所含的重金属离子一旦被人饮用将对人体造成严重的伤害,在其他用水领域也将引起各类不良后果,针对这一现状,专家学者均在努力开发新材料、新技术以及新方法处理水体中的重金属离子,以做好对水质量的把关,为社会生产生活提供尽可能优质的用水。其中,吸附是一个重要的发展方向,在此方面,进行最多的是对新的吸附材料和复合材料的探索和研究。
新形势下环保监察与环境监测联动机制构建思考
Authors: 吕 晓锋
Published: November 2019

基于新形势背景下,搭建环保监察与环境监测联动机制,能够将两者的积极作用发挥出来。本文对新形势下环保监察存在的主要问题进行阐述,从环境监测与环境监察的主要内容与关系展开分析,并以此为依据,提出明确环境监察与环境监测的原则、搭建完善的业务联动机制、搭建学习培训联动机制、提升环保工作科技的科技水平等几个方面的措施,希望充分的发挥出保护环境的效用,具体如下。
阜新地区一次大雾天气过程的分析
Authors: 白 佳宁 , 于 金环 , 史 洪杰 , 常 相伊
Published: November 2019

大雾为阜新地区在秋冬季节主要的灾害性天气,对交通、环境有着较大的影响,10月为阜新地区大雾多发季节。本文利用MICAPAS常规资料、自动站数据等资料分析了2019年22-24日阜新地区连续性大雾天气过程。结果表明：(1)此次大雾过程发生在500hpa较平直的纬向环流中,地面为弱高压控制,中低空偏南暖湿气流向阜新地区输送,为大雾的发展提供了有利的环流背景(2)大雾发生的过程中,地面为弱南风,微风使逆温层有一定厚度,有利于大雾的维持(3)低空逆温层使水汽不易扩散,近地面潮湿,对大雾的形成和维持有重要的贡献。(4)大雾发生时大气层结稳定,低层为弱的辐合上升,高层为弱的幅散下沉,有利于大雾的维持发展。
加强环境宣传教育提高公众环保意识探究
Authors: 周 卫华
Published: November 2019

环境保护要想深入人心,就必须发挥教育的作用,通过不同的宣传形式向公众普及环境保护法和保护环境的重要性,进而提升公众的环境保护意识。环保政工师必须要加强环境宣传教育与公众参与环境治理,完善公众参与环境治理,促进公众参与环境治理,建立在环境治理中的公众参与平台,加强实施公共环境信息披露,实现公众有效参与等。
营林生产中造林规划设计及造林技术探析
Authors: 梁 洁
Published: November 2019

随着可持续发展战略的深化,国家对于生态建设工作越来越重视,并对生态建设进行大量的投入,意在通过合理的营林生产活动,改善生态环境,推动林业的可持续发展。但这种目标的实现,还需要对营林生产活动进行有效的落实,通过科学的营林规划设计以及先进的造林技术,不断提升营林生产的质量,如此才能保证营林生产的健康性和可持续性。所以,本文就营林生产中的造林规划以及造林技术进行具体论述,希望能够为相关工作的有效开展提供一定的参考和借鉴。
Editorial
Authors: Al Ahwal Mahmoud S.
Published: November 2019

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Glycemic Control of Type 2 Diabetic Patients Managed in Tertiary Care Internal Medicine Clinics Using HbA1c
Authors: Alenezi Helal S. , Kharal Mubasher , Yousuf Muhammad , Al Saleh Yousef , Bin Salih Salih
Published: November 2019

Background /Objective: The aim was to assess the glycemic control in patients with type 2 diabetes mellitus using American Diabetes Association HbA1c definition of good control of â‰¤ 7.0%.

Methods: This retrospective study conducted in internal medicine outpatient clinics at King Abdulaziz Medical City in Riyadh, Kingdom of Saudi Arabia. All patients with type 2 diabetes mellitus attending the clinic from August 2005 to January 2006 were evaluated. Patients with HbA1c measured regularly and under anti-diabetic therapy were included in the study. Last measured HbA1c was used to evaluate diabetic control.

Results: Data for 968 (81.5%) patients out of 1188 were available for analysis. Only 211 (21.8%) patients had their HbA1c within the American Diabetes Association recommended target of HbA1c â‰¤ 7%. Mean HbA1c was 8.98%. Patients were stratified into groups of good (HbA1c £ 7%), average (HbA1c 7.1% - 9.9%) and poor diabetic control (HbA1c â‰¥ 10%) included 21.8%, 46.2% and 32.0% of the study population, respectively. Mean HbA1c in patients on diabetic diet only, oral hypoglycemic agents, insulin, and oral hypoglycemic agents plus insulin was 7.62%, 8.67%, 8.92% and 9.70%, respectively.

Conclusion: Majority of patients in our study did not meet the American Diabetes Association recommended target HbA1c for type 2 diabetes mellitus. Causes for this failure need to be assessed in Saudi type 2 diabetes mellitus population.
Do Patients Know Their Physicians' Names and Their Specialties? Results from King Abdulaziz Medical City, Riyadh, Saudi Arabia
Authors: Binsalih Salih , Al Harthi Omar , Qahtani Mohammad , Al Sayyari Abdullah
Published: November 2019

Objective: To determine if inpatients in medical wards are aware who their most responsible physician (MRP) is and what is the nature of his/her specialty and if this awareness is influenced by age, sex, method of admission and the length of hospital stay.

Methods: A cross-sectional study conducted at King Abdulaziz Medical City, Riyadh.

Results: One hundred patients completed the survey from 7 different wards. 66% were male and two-thirds of the patients were over the age of 60 years, and 55% were inpatients for more than 10 days. Overall respondents, 43% knew the name of their MRP whereas 57% did not.

Conclusion: Reduced awareness was more often observed in female gender, older age and being admitted through Emergency Department. It's recommended that MRPs' names on signboards be written in Arabic and English in all wards.
Dialysis Dementia:
Authors: Algahtani Hussein A. , Al-Rabia Mohammed W.
Published: November 2019

Dialysis dementia is a rare syndrome that was first described by Alfrey et al. in 1972. This disease is an entity nowadays, however, in Europe, between 1976 and 1977; the prevalence of dialysis dementia was 600 per 100,000 dialysis patients, although there was a wide variation between centers. The clinical picture is characterized by an insidious onset of altered behaviour, dementia, speech disturbance, myoclonus, tremor, asterixis, and convulsions. In this manuscript, an interesting case of dialysis dementia and review topic is presented.
Impulsive and Compulsive Behaviors in Parkinson's Disease:
Authors: Alshehri Abdulraheem M.
Published: November 2019

Parkinson's disease is a common neurodegenerative disease, with a worldwide incidence of about 10-20 in 100,000. Its diagnosis remains clinical, and it requires bradykinesia plus one of the following: Rest tremor, rigidity or postural instability. Dopaminergic therapy including levodopa and dopamine agonists has allowed a reasonable control over the motor symptoms, but it offered no help for the non-motor manifestations. To the contrary, dopaminergic antiparkinson therapy was the most likely culprit in the emergence of a new set of impulse control disorders including:  Pathological gambling, hypersexuality, compulsive shopping, compulsive eating, punding (complex, repetitive, excessive, non-goal oriented behaviors), walkabout, and dopamine dysregulation syndrome. A case series of three main impulse control disorders in Parkinson's disease is presented here with a review of the current thinking regarding diagnosis and treatment.
Essential Thrombocythemia: Current Molecular and Therapeutic Insights
Authors: Al-Sayes Fatin M. , Gauthaman Kalamegam
Published: November 2019

Essential thrombocythemia is one of the Philadelphia chromosome negative, clonal myeloproliferative disorders involving the hematopoietic stem cells and is characterized by elevated platelet counts and attendant thromboembolic phenomenon. A point mutation in the Janus-Activated Kinase 2 gene (JAK2V617F) accounts for nearly 50% of Essential thrombocythemia patients while about 10% have mutations in the thrombopoetin receptor (MPL) gene (MPLW515L/K). Several other genes are implicated, clearly indicating the existence of drivers both common and uncommon in the causation of Essential thrombocythemia. Genotyping for mutations will therefore be a useful diagnostic tool for detection of Janus-Activated Kinase 2 negative, MPL negative, Essential thrombocythemia patients. An integrated approach of systematic analysis leading to accurate diagnosis will enable risk stratification and institution of therapy following the World Health Organization guidelines. In addition to Janus-Activated Kinase inhibitors, a combination of agents that has anti-inflammatory properties could help prevention and/or reversal of fibrosis.
Improving Door to Needle Thrombolysis in Acute ST-Elevation Myocardial Infarction
Authors: Jabbad Husain H. , Elgaby Essam , Alama Mohammed N.
Published: November 2019

Background: Although primary percutaneous coronary intervention is the recommended method of reperfusion for ST-segment elevation myocardial infarction patients, thrombolytic therapy should still be given to ST-segment elevation myocardial infarction patients when anticipated delay in percutaneous coronary intervention is more than 120 minutes from first medical contact.

Objective: The aim of this study is to assess improvement of door to needle time in cases of ST-segment elevation myocardial infarction after applying new clinical pathway for cases of ST-segment elevation myocardial infarction presenting to Emergency Department at King Abdulaziz University Hospital over one year period.

Methods: A prospective study conducted at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, in patients with ST-segment elevation myocardial infarction who underwent thrombolysis from November 2012 to October 2013 to compare door to needle time obtained from this study with door to needle time from previous records during October 2010 till September 2011.

Results: A total of 93 patients with ST-segment elevation myocardial infarction received thrombolytic in Emergency Department. Mean age 50 years. Median door to Electrocardiogram 3 minutes, median Electrocardiogram to thrombolytic 25 minutes and door to needle time 30 minutes. 54.8% of patients received thrombolytic within 30 minutes or less.

Conclusions: Improvement in door to needle time for thrombolysis of cases of ST-segment elevation myocardial infarction has been achieved at King Abdulaziz University Hospital during the period of the study compared to previous data.
Transcatheter Closure of Saccular Coronary Artery Fistula
Authors: Bahaidarah Saud A. , Al-Ata Jameel
Published: November 2019

Coronary artery fistula is a rare entity of congenital heart disease but is the most common anomaly of coronary arteries. This is a case report of a 22-years-old female diagnosed with coronary artery fistula that underwent transcatheter closure of saccular coronary artery fistula.
Molecular Typing of Methicillin-sensitive and Methicillin-resistant Staphylococcus aureus: What Epidemiologists need to know from Plasmid Analysis to Whole Genome Sequencing.
Authors: Al-Zahrani Ibrahim A.
Published: November 2019

Methicillin-resistant Staphylococcus aureus is an important nosocomial pathogen. The early identification of an outbreak, making use of a rapid, precise and simple methicillin-resistant Staphylococcus aureus typing technique, can lead to prompt and effective precautions that avoid further spread of the infection. Pulsed-field gel electrophoresis is considered the gold standard for methicillin-resistant Staphylococcus aureus typing and has been recently supported by multilocus sequence typing. SmaI-multiplex polymerase chain reaction typing is a novel polymerase chain reaction -based technique that combines the principles of pulsed-field gel electrophoresis, with simplicity of polymerase chain reaction and can be used in many routine clinical laboratories. Whole genome sequencing typing is a second generation sequencing technology and may ultimately replace the traditional molecular typing methods. This review aims to survey existing molecular typing techniques for Staphylococcus aureus and to discuss information for each method in order to aid researchers and clinical professionals in the selection and implementation of an optimal technique.
Hidradenitis Suppurativa and Crohn’s Disease:
Authors: Khojah Abrar F. , Qari Yousif A.
Published: November 2019

Hidradenitis suppurativa is a rare chronic / recurrent, infl ammatory and suppurative disease that affects apocrine gland-bearing areas of the skin, including the axillae, inframammary fold, inguinal and anogenital regions. Few reports have described the co-occurrence of Hidradenitis suppurativa and Crohn’s disease and the challenge in managing patients with both conditions. We describe two cases in which HS developed during the course of Crohn’s disease in one patient, while it preceded the onset of Crohn’s disease in the other case. Both patients showed poor response to biological therapy although one case initially responded well to induction therapy with infliximab.
Protective Efffects of Melatonin in Corpus Callosum Astrocytes during Ischemia in Transgenic Mice
Authors: Alghamdi Badrah S.
Published: November 2019

Objective: Stroke is a leading cause of adult death and disability worldwide. Around 80% of all stroke cases are classed as ischemic stroke, which affects both gray and white matter brain regions. During ischemia, reactive oxygen species are generated and initiate multiple damaging processes such as lipid peroxidation, mitochondrial dysfunction, blood–brain barrier damage and brain edema. Melatonin is a potent antioxidant which can act as a direct oxygen species scavenger. Melatonin can also act at receptors (melatonin receptor 1 and 2), which are expressed in the nervous system cells including astrocytes.

Methods: Using live cell imaging of transgenic mice, the viability of astrocytes in the corpus callosum of adult brain sections was monitored during a standard 60 minutes period of modeled ischemia (oxygen-glucose deprivation) and 30 minutes of reperfusion in 8 groups; Control, artificial cerebrospinal fluid + Melatonin, oxygen-glucose deprivation, oxygen-glucose deprivation + Melatonin, oxygen-glucose deprivation + Melatonin + Luzindole (a nonselective melatonin receptor antagonist), oxygen-glucose deprivation + Luzindole, oxygen-glucose deprivation + Melatonin + propionamidotetralin (a selective melatonin receptor 2 antagonist), and oxygen-glucose deprivation + propionamidotetralin.

Results: Addition of melatonin significantly reduced the level of astrocyte death during oxygen-glucose deprivation from 71.94% ± 1.45 to 37.84% ± 1.9; p < 0.0001. This protective effect was blocked by luzindole or propionamidotetralin. Following known scoring categories for glial injury, ultrastructural morphology confirmed the protective effect of melatonin against acute ischemic injury in the white matter glial cells.

Conclusion: Melatonin is a promising neuroprotective agent during white matter ischemia.
What We Know so far about Obstructive Sleep Apnea Management: A Review Article
Authors: Alhejaili Faris F.
Published: November 2019

Obstructive sleep apnea is a common sleep disordered breathing condition. It is well recognized as a major risk factor for multiple medical conditions and poor quality of life. It has a great burden on health care resources and a substantial increase in health care use costs. Unfortunately, despite the prevalence, it is widely recognized that it remains under-diagnosed.

Effective treatment needs a comprehensive management plan approach that considers the patient as the centerpiece of management. Regular monitoring and a detailed follow up can have an impact on adherence to therapy. A constant and regular follow up can shed some light on patients who are not compliant with therapy and offer them with alternative therapeutic options that suits them better whenever feasible.

In this review, we aim to shed some light on where we are in terms of obstructive sleep apnea management strategies and options available to each individual patient.
Identifying and Prioritizing the Relationship Marketing Factors Affecting the Customer Satisfaction with Services Section of the Tejarat Bank through the Application of Q Methodology
Authors: Moghaddam Ali Tohidi
Published: November 2019

The present research project aims at studying the impressions and beliefs of the customers of Tejarat Bank in order to identify and prioritize the factors of relationship marketing which help increase the satisfaction of the customers with the service section of Tejarat Bank of Hamadan, Iran. It is a mixed exploratory study conducted based on Q methodology. The statistical community of the study comprised all the customers of the central branch of the bank who had, at least, one kind of account in it and were considered as active customers. Finally 30 customers were aimfully selected for the study by using a focused group discussion technique. Based on the interviews conducted with the customers through focused group discussions, 21 Q phrases were extracted. The phrases were then handed out to the customers in the form of a questionnaire with 21 items and an answer sheet (Q diagram). They were asked to give their agreement or disagreement with the items provided. Then after collecting the data which were gained through regulating the Q, they were analyzed by using factor-analysis method. The results thus found showed that the customers have introduced the five cases of trust, commitment, conflict handling, relationship and competence as the main factors of relationship marketing. The identified factors were then prioritized, and this showed that, from the viewpoints of the customers, the variables of trust, commitment and conflict handling were the most important ones in increasing the customer satisfaction.
Analysis of Economic Growth and Structural Changes and the Implication for Choice of Development Strategy: A Case Study of Pasaman Regency
Authors: Adrimas Adrimas , Amali Rivai Harif , Sartika Dewi
Published: November 2019

The average economic growth rate of Pasaman Regency before the administrative division (1993-2002) was 5.8%, then after the division increased slightly to an average of 5.9%. This figure is far lower than the rate of growth of the New Autonomous Region of West Pasaman Regency (6.4 %). After the division, agricultural and mining sectors became more dominant in the economy of Pasaman making up 54.6% but the contribution of the manufacturing sector declined sharply from 10.3% to 4.6% as most of the existing Pasaman processing industry became part of West Pasaman. The comparative advantages of Pasaman Regency are mainly in the sectors: agriculture, forestry and freshwater fisheries. The district’s economic growth is mainly influenced by factors originating from outside the region as indicated by the relatively high regional-share component of 159%. While regional division has benefited West Pasaman, it has provided no significant benefit for the parent region which can still be categorized as underdeveloped. An analysis of the Klassen Typology Matrix indicates that policies and programs that are relevant for the development of disadvantaged areas should be directed at providing employment through the use of labor-intensive technologies. This development should focus on agriculture, forestry and freshwater fisheries producing products with a significantly extensive market.
The Influence of Partial Replacement of Some Selected Pozzolans on the Drying Shrinkage of Concrete
Authors: C. M. Ikumapayi , S. L. Akingbonmire , O. Oni
Published: November 2019

Concrete is prone to cracking and one of the major causes of cracking is drying shrinkage of the hardened concrete. This research work was carried out to study the influence of partial replacement of some selected pozzolans on the drying shrinkage of concrete. Four pozzolans used in this study, were made to replace cement at various percentages resulting in various concrete mixes. Setting time test was conducted for the various cement mixes using Vicat’s apparatus and drying shrinkage test was done for the concrete test specimens. The results of the setting time indicate that partial replacement of pozzolans with ordinary Portland cement increases both the initial and final setting time of cement as the percentage replacement increases. Similarly, drying shrinkage results show that concrete made with Groundnut Shell Ash (GSA) and Locust Bean Pod Ash (LBA) at 12% replacement will have a stable and better shrinkage resistance than the control at both 56 days and 90 days. Meanwhile, the control concrete gives a better drying shrinkage at 28 days curing. In conclusion, the results show that pozzolanas [Bamboo Leaves Ash (BLA), Locust Bean Pod Ash (LBA), Sugarcane Bagasse Ash (SBA) and Groundnut Shell Ash (GSA)] can successfully replace cement up to 12% without necessarily affecting the shrinkage ability of the produced concrete. It also shows that Groundnut Shell Ash (GSA), Locust Bean Pod Ash (LBA) and Bamboo Leaves Ash (BLA) are more resistance to drying shrinkage than the control.
Incidence of sweetpotato viruses in Central Luzon, Philippines
Authors: Vasquez Erlinda , Palomar Manuel , Laranang Lilibeth
Published: November 2019

Sweetpotao commercial growing areas in Central Luzon particularly Tarlac and Bataan were surveyed for the incidence of sweetpotato viruses. Healthy-looking sweetpotato leaves and those showing symptoms of virus infection were collected and subjected to nitrocellulose membrane-enzyme linked immunoabsorbent serological assay (NCM-ELISA) for the detection of known viruses using the kit and protocol from Centro Internacional de la Papa, Lima Peru. The NCM-ELISA detected sweetpotato feathery mottle virus (SPFMV), sweetpotato mild mottle virus (SPMMV), sweetpotato latent virus (SPLV), sweetpotao chlorotic fleck virus (SPCFV), C-6 virus, sweetpotato mild speckling virus (SPMSV), sweetpotato caulimo-like virus (SPCalV), and sweetpotato chlorotic stunt virus (SPCSV). Six to 8 viruses were found in Tarlac and 3-4 viruses in Bataan. Highest infections were recorded for C-6, SPMSV, SPCalV and SPCSV reaching 100% in almost all areas. Infection of SPFMV ranged from 45-70%. The combination of SPFMV with other viruses was common registering 40-70% complex infection. Mixed infection of 3-6 viruses (SPFMV, SPMMV, SPLV, C-6, SPMSV and SPCalV) was found in Tarlac and 2-4 viruses (SPFMV, C-6, SPMSV and SPCalV) in Bataan. Practically all sweetpotato growing areas of Tarlac are “hotspot” areas of sweetpotato viruses.
Appropriation of the information and communication technologies by farmers and extension workers in Borongan, Eastern Samar
Authors: Alviola Ulderico , Cagasan Editha
Published: November 2019

This study aimed to describe how the information and communications technologies (ICTs) are being appropriated or adapted by farmers and extension workers to fit their day-to-day activities and to find out the consequences of using ICTs from the point of view of farmers and extension workers.
This study followed a qualitative case study design. Informants were identified using the snowball sampling technique. A total of 23 informants were interviewed, 13 of which were farmers and 10 were extension workers. Data were gathered using in-depth and unstructured interviews.
The grounded theory analysis was used to generate a model that describes how ICTs are appropriated by farmers and extension workers in Borongan, Eastern Samar. As shown by the model, the primary intentions for using ICTs were not agriculture-related. But because of certain facilitating factors, ICT use was later modified to fit the needs and lifestyle of farmers and extension workers. Their use of ICTs for agricultural purposes led to the following consequences: 1) savings in money and time; 2) fast access to information and instant communication; 3) convenience; 4) increased knowledge; 5) easier and faster accomplishment of job; 6) improved livelihood; 7) lessening of worries, dismay and embarassment; 8) increased demand for information and technical assistance from clients and 8) people’s increased interest to learn.
Iron Bacterial Phylogeny and their Execution Towards Iron Availability in Equatorial Indian Ocean and Coastal Arabian Sea
Authors: RAJASABAPATHY RAJU , MOHANDASS CHELLANDI , VIJAYARAJ AJAKKALAMOOLE SRINIVAS , MADIVAL VARSHA VINAYAK , MEENA RAM MURTI
Published: November 2019

Based on distinct colony morphology, color, size, shape and certain other traits, 92 bacterial isolates were investigated to understand their managerial ability on iron from the Arabian Sea and Equatorial Indian Ocean samples. The ARDRA (amplified rDNA restriction analysis) applied to eliminate the duplication of the bacterial strains, resulted 39 different banding patterns. The 16S rRNA gene sequencing data indicate the dominancy of three phylogenetic groups, alpha-Proteobacteria (10.25%), gamma-Proteobacteria (35.89%) and Bacilli (53.84%) in these waters. Marinobacter and Bacillus were the only common genera from both of the regions. Pseudoalteromonas, Halomonas, Rheinheimera, Staphylococcus and Idiomarina were some of the other genera obtained from the Arabian Sea. Erythrobacter, Roseovarius, Sagittula and Nitratireductor were found mostly in Equatorial Indian Ocean. In addition, 16S rRNA gene sequence data of some of our iron bacterial strains belong to novel species and one isolate ASS2A could form a new genus. Close to 23% of the isolates were able to produce high affinity sets of ligands like siderophores to mediate iron transport into the cell. The current study indicated that the Equatorial Indian Ocean species were well adapted to oxidize iron as an electron acceptor and the Arabian Sea species preferably go through siderophore production.
Uropathogenic Escherichia coli Isolates with Different Virulence Genes Content Exhibit Similar Pathologic Influence on Vero Cells
Authors: OBAID JAMIL M.A.S. , MANSOUR SAMIRA R. , ELSHAHEDY MOHAMMED S. , RABIE TARIK E. , AZAB ADEL M.H.
Published: November 2019

Uropathogenic Escherichia coli are the major causative agent of urinary tract infection--they may simultaneously express a number of virulence factors to cause disease. The aim of this study was to investigate the relation between virulence factors content of fifteen UPEC isolates and their pathogenic potential. The isolates belonged to the five serotypes O78:K80, O114:K90, O142:K86, O164 and O157. Nine of the virulence factors have been explored, ibeA, pap, sfa/foc, cnfl, hly, fyuA, pil, ompT and traT. Virulence factors profiling of the isolates revealed a different content ranging from 22% to 100% of the virulence genes explored. The pathogenic capacity of all fifteen isolates when tested on Vero cells showed that the cytotoxicity for all tested strains on Vero cells was approximately equal and enhanced after growth in syncase broth, leading mainly to cell lysis. The toxic effects reduced slightly after heat treatment of the toxin, and greatly after formalin detoxification, but not all the deleterious effect was abolished. Endotoxin also has cytotoxic effects on Vero cells, but longer time is needed for cytolysis which is greatly diminished with formalin treatment. In conclusion, our study revealed that pathogenic strains of UPEC can exert their pathogenic effect on live cells or system with limited virulence factors gene content.
Molecular Analysis of JC Polyomavirus Genotypes Circulating among Tribal Populations of North-Eastern West Bengal, India
Authors: CHATTARAJ SUTANUKA , BHATTACHARJEE SOUMEN
Published: November 2019

There is a resurgence of interest in the study of occurrence, genotype and pathogenic associations of human Polyomaviruses in recent years. In the present study, we have ascertained the presence of human Polyomavirus JC (JCV) in the urine and peripheral blood leukocytes of tribal populations, for the first time in the North-Eastern part of West Bengal State of India. We have also characterized the prevalent genotypes of the non-coding controlregions (NCCRs) of these natural isolates. The result suggests a high incidence of JCV reactivation in the populations assayed. Approximately 25% of the non-immunocompromized tribal men and women, tested positive based on polymerase chain reaction (PCR) analysis, and these results were further confirmed by sequencing of PCR products. Pairwise sequence comparison and alignment of the NCCR sequence of these Indian strains appeared to be comparable and related to the archetypal JCV (CY) and the Tibetan LH3 strains, with some alterations in few key positions. The sequence analyses were done with regard to transcription factor binding to DNA sequence elements of endemic JCV NCCRs.