bluuebunny/crossref_metadata_2025 huggingface dataset:
Parameter Evaluation and Application Demonstration of a New Type of Blood Vacuum Tube Cap Opening and Closing Machine
Authors: PU Rong , PU Meicen , XIN Qingsong , CHEN Feng
Published: June 2020

Background: We aimed to evaluate the basic performance and basic parameters of a new type of blood vacuum tube cap opening and closing machine for further application. Methods: From July 2013 to March 2018, 110, 000 cases involved in the clinical trials in Third People's Hospital of Dongguan City were selected as the instrument group, and 10,000 cases were selected as the manual operation group. The application demonstration and instrument performance assessment were performed by five units. Unified evaluation indicatory system and the standard of assessment were set up. The instrument assessments and demonstration tests were carried out by these 5 units. Finally, the basic parameters of the instrument were analyzed and compared. Results: The new instrument had excellent performance, and thirty parameters were excellent. Five patents had been granted already. There were no differences between the instrument groups in different units, and among different units. However, there were some differences in the manual operation group between different units. The average cap opening time was 21 "04 in the instrument group, and 152" 48 in the manual operation group (P<0.05); the cap closing time was 18 "56 in the instrument group, and 104"24 in the manual operation group (P<0.05). The instrument group outperformed the manual operation group in cap closing time, pollution rate, spill rate and failure rate (P<0.01). The design of the instrument was original. Conclusion: This blood vacuum tube cap opening and closing machine can perform a wide variety of functions, and it is stable, intelligent and superior to manual operation. More efforts need to be made for the industrialization of this instrument.
Influencing Mechanisms of Urban Heat Island on Respiratory Diseases
Authors: HUANG Huanchun , YANG Hailin , DENG Xin , ZENG Peng , LI Yong , ZHANG LuNing , ZHU Lei
Published: June 2020

Background: Urban heat island (UHI) is being intensified with the progress of urbanization. Meanwhile, respiratory diseases caused by high temperature become common. This study explores the influences of UHI on respiratory diseases (J00-J99) and the evolutionary characteristics of the spatial pattern of such influences. Methods: The pattern–process–function and the influencing mechanism of UHI on respiratory diseases were evaluated through landscape pattern indexes from 1992 to 2018 in Tianjin, China. The basis was on data from Landsat TM/OLI/TIRS remote-sensing images, meteorological stations, and mortality of respiratory diseases. Results: The fluctuating influence of UHI on the respiratory diseases in Tianjin has increased from 1992 to 2018, showing a significant phase-based characteristic. During 2011-2018, the influence has soared greatly, and mortality risk has increased by 101%, and the influenced area has reached 349 km². Furthermore, the regional space clustered, and the influenced patches are in irregular shape, and the highly influenced area is enlarged. Moreover, the indexes of the landscape level of the influenced areas all decrease. The patches at all levels are fragmented and distributed discontinuously. Spatially, the influenced areas gradually extend from the urban center to the suburbs. Conclusion: UHI causes a higher mortality of respiratory diseases because it increases daily average air temperature in summer. With respect to landscape pattern, the influenced areas at low level is highly interconnected and relatively concentrated, whereas the influenced area at high level is distributed in clusters. In general, the influenced area is fragmented and discontinuously distributed in urban center.
Association Study between Functional Polymorphisms of MMP9 Gene Promoter and Multiple Sclerosis Susceptibility in an Iranian Population
Authors: SABBAGH Sima , NADEALI Zakiye , SHAYGANNEJAD Vahid , REZVANI Majid , SABOORI Masih , GANJI Hamid , TAHANI Soheil , DEHGHANI Farzaneh , HOSSEINZADEH Saman , MARZBANI Elnaz , SHAFIEI Peiman
Published: June 2020

Background: Matrix metalloproteinase-9 (MMP-9) polymorphisms, C−1562 T and -90 (CA) n repeats, which influence transcriptional activity of this gene, are proposed to play a role in MS susceptibility and its development. In the present study, the possible association of MMP-9 polymorphisms in Iranian MS patients is studied. Methods: Association of MMP-9 mentioned gene polymorphisms with MS susceptibility was evaluated in unrelated Iranian subjects referred to Al-Zahra Hospital, Isfahan, Iran during 2014 to 2017. Results: -1562 T allele of MMP-9 was associated with increased MS risk. However, we found no overall significant effect of −90 (CA)n repeat on MS susceptibility. Conclusion: For as much as MMP-9 molecule is a potential target for MS therapy, to determine whether any of MMP-9 polymorphisms influence MS susceptibility in Iranian MS patients or not, concerning the significant influence of T allele on MS susceptibility and the non-significant association regarding CA repeats, further research is needed before proposing any definite conclusion.
Screening of 10 DFNB Loci Causing Autosomal Recessive Non-Syndromic Hearing Loss in Two Iranian Populations Negative for GJB2 Mutations
Authors: KOOHIYAN Mahbobeh , REIISI Somayeh , AZADEGAN-DEHKORDI Fatemeh , SALEHI Mansoor , ABTAHI Hamidreza , HASHEMZADEHCHALESHTORI Morteza , NOORI-DALOII Mohammad Reza , TABATABAIEFAR Mohammad Amin
Published: June 2020

Background: Autosomal recessive non-syndromic hearing loss (ARNSHL), one of the global public health concerns, is marked by a high degree of genetic heterogeneity. The role of GJB2, as the most common cause of ARNSHL, is only <20% in the Iranian population. Here, we aimed to determine the relative contribution of several apparently most common loci in a cohort of ARNSHL Iranian families that were negative for the GJB2 mutations. Methods: Totally, 80 Iranian ARNSHL families with 3 or more affected individuals from Isfahan and Hamedan provinces, Iran were enrolled in 2017. After excluding mutations in the GJB2 gene via Sanger sequencing, 60 negative samples (30 families from each province) were analyzed using homozygosity mapping for 10 ARNSHL loci. Results: Fourteen families were found to be linked to five different known loci, including DFNB4 (5 families), DFNB2 (3 families), DFNB7/11 (1 family), DFNB9 (2 families) and DFNB3 (3 families). Conclusion: Despite the high heterogeneity of ARNSHL, the genetic causes were determined in 23.5% of the studied families using homozygosity mapping. This data gives an overview of the ARNSHL etiology in the center and west of Iran, used to establish a diagnostic gene panel including most common loci for hearing loss diagnostics.
Trends of Obesity in 10-Years of Follow-up among Tehranian Children and Adolescents: Tehran Lipid and Glucose Study (TLGS)
Authors: HOSSEINPANAH Farhad , SERAHATI Sara , BARZIN Maryam , ARYANNEZHAD Shayan , REZAIE Maryam , VALIZADEH Majid , AZIZI Fereidoun
Published: June 2020

Background: We aimed to investigate the trend of childhood obesity in Tehranian population during a median follow-up of 10 years. Methods: Within a prospective cohort study, using data collected from Tehran Lipid and Glucose Study (TLGS), 1406 participants, aged 3-11 yr were selected and monitored in 4 phases: phase I (1999-2001), phase II (2002–2005), phase III (2006–2008) and phase IV (2009–2011). Results: Total prevalence of obesity in children increased from 5.5% to 9.4% from phase I to IV. Performing GEE (Generalized Estimating Equation) analysis, relative risk of obesity was calculated, comparing each phase to its previous phase: phase II in reference to phase I (RR=1.06, CI=1.04-1.08), phase III in reference to phase II (RR=1.01, CI=1.00-1.03) and phase IV in reference to phase III (RR=0.96, CI=0.94-0.98). Between group difference was significant in all subgroups (age, gender, parental obesity) except parental education. Test of interaction for effect of time was insignificant in all subgroups except for the age group. For children younger than 7 yr old at phase I, trend of obesity throughout the study was higher compared to those with 7 yr of age and older at phase I. Conclusion: During a decade of follow-up, trend of obesity was rising in this Tehranian children in both genders, especially in younger children. Any preventive interventions for stopping this trend should focus on early stages of childhood.
Genetic Polymorphisms of Glutathione S-Transferases T1 (GSTT1) and M1 (GSTM1) in Iranian Mandaeans Population
Authors: BOROUMAND Fariba , ZARGHAMI Mahdis , SAADAT Mostafa
Published: June 2020

The article's abstract is no available.
Species Variety, Antibiotic Susceptibility Patterns and Prevalence of Enterotoxin Genes in Staphylococci Isolated from Foodstuff in Central Iran
Authors: HOVEIDA Laleh , ATAEI Behrooz , AMIRMOZAFARI Nour , NOORMOHAMMADI Zahra
Published: June 2020

Background: The presence and diversity of Staphylococcus species and their enterotoxin-encoding genes in foodstuffs have not been comprehensively studied in some developing countries. This study aimed to assess the frequency of Staphylococcus spp. and their related virulence factors in foodstuffs in Isfahan, Iran. Methods: Overall, 139 foodstuff samples, collected from Isfahan City (center of Iran) from Sep 2015 to Oct 2016, were processed for the presence of Staphylococcus spp. using standard bacteriological procedures and sequence analysis of 16S rRNA gene. Antimicrobial susceptibilities and prevalence of mecA and toxin-encoded genes (sea, seb, sed, see and tsst1) were tested for all of the Staphylococcal isolates. Results: Forty-four Gram-positive cocci were recovered from 139 dairy and meat samples. The most prevalent species were S. vitulinus 25.0% (11/44) and S. aureus 20.5% (9/44); respectively. The most prevalent antimicrobial resistance was noted towards penicillin, cefoxitin and tetracycline. The sec, sea, see and tsst1 genes were found in 19%, 9.5%, 3.5%, and 3.5% of the isolates, respectively. Conclusion: Numerous virulence factors were detected in different Staphylococcus spp. isolated from foodstuffs, more attention should be paid to the presence of the bacteria. Proper hygienic and management practices should be considered in order to increase food safety and prevent extra treatment costs.
Nutritional Intake and Chronicity Associated with the Old World Cutaneous Leishmaniasis: Role of Vitamin A
Authors: GOYONLO Vahid MASHAYEKHI , NOROUZY Abdolreza , NEMATI Mohsen , LAYEGH Pouran , AKHLAGHI Saeed , TAHER Ahmad Reza , KIAFAR Bita
Published: June 2020

Background: Old world cutaneous leishmaniasis (CL) is known as a self-healing cutaneous parasitic infection. Host immunity has a fundamental role in the course of this infection. This study was designed to investigate the relationship between nutritional status and vitamin A intake with the clinical course of CL. Methods: Overall, 250 patients with CL attending a dermatology clinic in Imam Reza Hospital Mashhad, Iran, were enrolled from Apr 2011 to Aug 2012. For data gathering, a semi-quantitative 302-item food frequency questionnaire was utilized. They received routine treatment protocols for leishmaniasis and 1 year of follow-up Results: As for the 149 patients who completed the study, a deficiency of macro and micronutrients, particularly vitamin A, was significantly related to a chronic clinical disease course. Conclusion: Imbalanced or insufficient nutritional intake including vitamin A deficiency, may influence the clinical course of CL.
Primary Long Distal Fitting Bipolar Hemiarthroplasty for Unstable Intertrochanteric Fracture in Elderly Patients
Authors: Zandi Reza , Karimi Amin , Sadighi Mehrdad , Minator-Sajjadi Mohammadreza , Okhovatpour Mohammad Ali , Ebrahimpour Adel , Fazeli Mehdi
Published: June 2020

Background: Intertrochanteric fracture in elderly patients is a frequent problem and is becoming more prominent as the proportion of this injury increases. The ideal treatment for an unstable intertrochanteric femoral fracture in senile osteoporotic patients remains controversial.
Methods: Seventy-five patients (over 70 years of age) with unstable intertrochanteric fractures were randomized into three groups and treated with three different procedures including long-stem bipolar hemiarthroplasty, proximal femoral nail (PFN), and dynamic hip screw (DHS). Estimated blood loss, duration of the operation, time of full weight-bearing, and Harris Hip Score (HHS) were determined for each patient.
Results: Surgical time was longer in hemiarthroplasty group, but the HHS and time from surgery to mobilization in these patients were significantly superior to the two other groups. PFN group had the lowest bleeding volume during surgery. Revision surgery was lower in hemiarthroplasty compared to the internal fixation, although it was not statistically significant.
Conclusions: In elderly patients with an unstable intertrochanteric femoral fracture who cannot tolerate long immobilization time, primary long distal fitting bipolar hemiarthroplasty is a valid treatment option for faster mobilization, good clinical efficacy, and satisfactory functional outcome.
Scoliosis Correction Surgery in Collagen Type VI Dysfunction
Authors: Mirzashahi Babak , Mohammed Yaseen Khan Furqan , Gharakhan-Maleki Rasul
Published: June 2020

Background: Collagen VI (COLVI) dysfunction results in a combination of connective tissue and muscular disorders. Spinal involvement and development of scoliosis precede loss of ambulation and respiratory deterioration in these patients. Therefore, spinal deformity correction surgery is warranted to preserve ambulation and respiratory function.
Case Presentation: A twelve-year-old girl presented with progressive scoliosis accompanying respiratory deterioration, sitting imbalance, and wheelchair-bound. The patient demonstrated an array of overlapping phenotypes related to COLVI dysfunction, including developmental delay, muscular dystrophy (MD), fatty replacement of skeletal muscles, and reduced bone mineral density to mention few. Patient was diagnosed with COLVI dysfunction caused by COLVI alpha 2 (COL6A2) gene mutation. She had severe phenotype expression similar to Ullrich congenital MD (UCMD). A Cobb angle of 85 degrees and thoracic kyphosis of 40 degrees were recorded. Surgical correction was performed in form of spinal fusion from T4 to S1 in addition to multiple level vertebral osteotomies.
Conclusions: Respiratory distress and ambulatory problems are life-endangering events in these patients. As the disease progresses and respiratory distress increases, anesthesia becomes more difficult and the risk of surgery increases. Therefore, early intervention for correction of scoliosis is warranted to support the quality of life. Surgical time has to be kept as short as possible to minimize blood loss in these patients.
XXV Aniversario
Authors: Ramírez M. Rafael
Published: June 2020

Modesta iniciación, supervivencia accidentada y superación permanente han caracterizado a esta Revista; cuando, hace 25 años, la ofrecíamos a todos los especialistas del país esperábamos su desarrollo al ritmo de los adelantos científicos y así́ ha sido.
Espátulas para la extracción fetal un nuevo instrumento obstétrico.
Authors: Velasco Chiriboga Alvaro
Published: June 2020

André Levret, en 1747 y William Smellie en 1751 (3) hacen la modificación más importante que hasta hoy se le imprime al fórceps, ésta es, la curva pélvica. Hasta entonces el fórceps tipo Chamberlein, habíase mantenido sin cambios substanciales, en una época que podría denominarse, el siglo del fórceps, por la gran variedad que de ellos hubo.
Bactrim 'Roche' en infecciones de las vías urinarias
Authors: Meléndez Libardo , Salas Gustavo , Acevedo Antonio
Published: June 2020

El efecto antimicrobiano de la asociación de sulfametoxazol y trimetoprim (BACTRIM 'Roche') fue estudiado en 17 pacientes con infecciones de vías urinarias. Se encontró́ que la asociación en la proporción presentada en el producto BACTRIM 'Roche', fue de resultados excelentes en ocho de los casos, buenos en seis e insatisfactorios en tres. Dos de los tres casos con respuesta insatisfactoria fueron pacientes con uropatia obstructiva crónica. No se encontraron reacciones alérgicas ni efectos colaterales importantes, diferentes de molestia gástrica. Nuestro estudio permite concluir que el preparado BACTRIM 'Roche', con 80 mg. de Trimetoprim y 400 mg. de Sulfametoxazol por comprimido, en dosis de dos comprimidos cada doce horas y por un mínimo de cinco días es una forma eficaz de tratamiento de infecciones de vías urinarias. Los autores recomiendan sin embargo constatar la mejoría ocuración del estado infeccioso mediante estudios bacteriológicos apropiados. En casos crónicos o recidivantes estos estudios deberán repetirse periódicamente.
Amenorrea - Ponencia oficial
Authors: Del Corral G. Fernando , Zúñiga C. Jorge E. , De la Cruz Jairo , Botero Augusto , Medina Rafael , Villegas Hugo
Published: June 2020

El presente estudio comprende el análisis de 148 casos de pacientes que consultaron o fueron remitidos a la consulta especializada de Ginecología Endocrina del Hospital Universitario del Valle Departamento de Obstetricia y Ginecología Facultad de Medicina Universidad del Valle.
El BACTRIM 'Roche' en el tratamiento de las infecciones del tracto urinario en pacientes hospitalizados. Estudio comparativo.
Authors: De Obstetricia y Ginecologia Federación Colombiana
Published: June 2020

En este estudio, llevado a cabo en un hospital general de Inglaterra, se utilizó la sinergia, ya comprobada, entre el sulfametoxazole y el trimetoprim. Cuando estas dos sustancias se utilizan en proporciones Óptimas, como ocurre en el BACTRIM 'Roche', la acción bacteriostática de cada componente se convierte en acción bactericida.
Estudio bacteriológico de secreción vaginal en 200 niñas asintomáticas, menores de 12 años
Authors: Duarte Contreras Alberto , Rodríguez Pelayo Rafael , Castro Omaña Aurora
Published: June 2020

En los estudios de la literatura universal que conocemos sobre secreción vaginal en niñas asintomáticas se acepta la presencia de un buen número de microorganismos, pero ninguno de ellos establece cuál sea la flora "saprofita normal".
El dispositivo intrauterino como anticonceptivo post-aborto
Authors: Edelman David A. , Goldsmith Alfredo
Published: June 2020

En América Latina el aborto inducido ilegal es uno de los mayores problemas de Salud Publica ( 1). Por ejemplo, en algunas ciudades colombianas se ha estimado que el número anual de abortos inducidos es casi igual al número de partos de término (2).
La amputación del cuello uterino en el tratamiento del Carcinoma In Situ
Authors: Peralta Armando , Camacho Emilio , Cabrera J. , Pacheco E. , Casanova Carmen Luisa
Published: June 2020

El tratamiento del Carcinoma in Situ va desde el tratamiento radiante hasta la histerectomía total con un manguito vaginal a los tratamientos conservadores como son la amputación de cuello, la exéresis parcial, la conización (4), la electrocirugía (5,12), y más modernamente la crío cirugía.
Discurso pronunciado ante la Academia de Medicina por el profesor Alvaro Velasco Chiriboga al recibir el premio nacional de medicina "Federico Lleras Acosta" en diciembre 4 de 1975
Authors: Velasco Chiriboga Alvaro
Published: June 2020

Quiero manifestar mis profundos sentimientos de gratitud al Jurado Calificador del Premio "Federico Lleras Acosta", por la honrosa distinción que me han dispensado al contribuir, como Profesor universitario, a preservar la integridad psicosomática del Hombre, protegiéndole durante su nacimiento.
Prevención del síndrome de dificultad respiratoria en prematuros. Estudio comparativo entre Orciprenalina y Betametasona
Authors: Cifuentes B. Rodrigo , Rey Humberto , Quintero Carlos A. , Montaño Luis E.
Published: June 2020

En el presente trabajo se puede observar cómo los recién nacidos que recibieron el fármaco beta estimulante tuvieron mejor puntaje de Apgar que en el grupo control.Lo anterior nos lleva a sugerir que la terapia con beta adrenérgicos tales como la Orciprenalina en infusión I.V. continua, se deben utilizar en amenaza o trabajo de parto prematuro, no solamente con el objetivo de disminuir o inhibir la contractilidad uterina, hecho suficientemente demostrado por varios investigadores (2), sino también porque en caso de que la paciente progrese al parto, hay menores probabilidades de hipoxia y de isquemia pulmonar fetal con menor incidencia de Síndrome de Dificultad Respiratoria Idiopática en el recién nacido.Igualmente aconsejamos su uso en pacientes en las cuales por cualquier circunstancia de orden obstétrico debe interrumpirse el embarazo prematuramente, como por ejemplo, en la Isoinmunización severa por Rh o en la Diabetes clases C en adelante (de Priscila White).Finalmente es de destacar también que, en nuestra muestra seleccionada al azar y sin patología materna o fetal, no observamos efectos colaterales nocivos, con excepción de los ya conocidos efectos cardiovasculares de los fármacos beta adrenérgicos, los cuales son pasajeros y bien tolerados por las pacientes.
Cesárea por incisión transversa suprapúbica
Authors: Amorocho P. Néstor , Restrepo R. Hernán
Published: June 2020

1.Se describe la técnica de laparotomía transversal (Pfannenstiel) con algunas modificaciones propuestas por los autores, para ser utilizada en la operación Cesárea.2.Se muestra la evperiencia de los autores en más de cien casos operados con dicha técnica.3.Se relaciona una incisión que brinda magnífico resultado estético con el tiempo quirúrgico, que considerado para la extracción fetal, es muy similar al de la incisión vertical tradicional.4.Los autores no encontraron en los casos estudiados problemas de eventración, que reportada por otros trabajos ha sido de muy baja incidencia.5.Se consigue con esta técnica una deambulación precoz post-operatoria, la cual no solo es posible sino también beneficiosa, ya que la incisión de piel coincide con las líneas de Langer y la anatomía de la pared abdominal, estimulada por la dinámica, tiende a cerrar mejor la herida quirúrgica.6.Esta incisión de Pfannenstiel, con las modificaciones propuestas, brinda un campo quirúrgico que satisface completamente el requerido para la intervención Cesárea.7.Se analizan estados de los fetos obtenidos y la morbilidad materna, utilizando la técnica descrita para Cesárea.8.Se considera y concluye que es una técnica recomendable por ser fácil, rápida, estética y fisiológica.
Mortalidad perinatal. - Estudio de muestreo
Authors: Rodríguez Soto Arturo , Muñoz González Luis Armando , Támara Ossa Alfredo , Lagos Galindo Manuel
Published: June 2020

Habiendo analizado las cifras de mortalidad perinatal en los países desarrollados y en los países subdes- arrollados, en los cuales las tasas de mortalidad oscilan entre 35 y 50 x l.000 (9, 10) con posibilidades de sub-registro, y teniendo en cuenta que las cifras altas de mortalidad pe- rinatal son el resultado de condicio- nes soc io-económicas y culturales ( l , 2, 3, 12), iniciamos un estudio pros- pectivo de muestreo en el Instituto Materno Infantil de Bogotá el cual atiende en su mayor parte a pacien- tes de baja condición socio-económi- ca y que en su mayoría concurren por primera vez a la Institución en el momento del trabajo de parto, cuan- do ya están en evolución afecciones graves maternas o fetales.
Nuevas tijeras para uso Obstétrico
Authors: Díaz Rodríguez Israel
Published: June 2020

Para que una episiotomía pueda ser anatómicamente bien reparada, para que no exista la posibilidad de que deje de cicatrizar, para que pos-teriormente no produzca dispareunia y para que finalmente sus bordes resulten netos y sin magulladuras, el instrumento con el cual se ha de verificar, debe ser cortante; es decir, de filo nítido.
Servicio científico ROCHE
Authors: De Obstetricia y Ginecología Federación Clombiana
Published: June 2020

El BACTRIM es una asociación de sulfametoxazol y trimetoprim. El primero inhibe el ácido para-aminobenzóico que es necesario para el desarrollo de los gérmenes, ejerciendo de este modo una acción bacteriostática. El trimetoprim es un derivado de la pirimidina e inhibe la síntesis bacteriana del ácido fólico que desempeña papel fundamental en el metabolismo
Adolescencia morfología de la adolescencia
Authors: Cardona Arango Fernando
Published: June 2020

Los procesos biológicos, como todos los fenómenos naturales se suceden en forma gradual a veces casi imperceptiblemente. A la oscura noche le sigue el claro amanecer y luego el brillante día sin que se pueda definir el minuto exacto en que termina la una y principia el otro. Así mismo en el organismo humano a la niñez le sigue la adolescencia y luego el ser adulto sin que se pueda señalar la fecha exacta en que termina una etapa y se inicia la otra.
Una técnica quirúrgica para corregir el prolapso de los órganos pélvicos
Authors: Mora Acevedo Rafael José Francisco , Medina Rivera Julián
Published: June 2020

Se describe una técnica quirúrgica para la corrección del prolapso de los órganos pélvicos y se presentan los resultado obtenidos en 15 intervenciones. Se establece una comparación con las técnicas quirúrgicas más empleadas en el momento actual.
Mortalidad Materna
Authors: Sánchez Torres Fernando
Published: June 2020

Se presentan los resultados del estudio exhaustivo de las muertes maternas ocurridas en el Instituto Materno Infantil, de Bogotá, durante un período de cinco años consecutivos 1971 a 1975, inclusive) En este lapso se registraron 372 fallecimientos, pero se descartaron once por haber ocurrido después de 42 días de terminado el embarazo. El estudio estuvo a cargo de un Comité Permanente de Mortalidad Materna y los diagnósticos finales estuvieron respaldados en el 75% de los casos por el respectivo protocolo de autopsia.La tasa de mortalidad materna encontrada fue de 30.47 por 10.000 nacidos vivos. De acuerdo a la clasificación de la FIGO, 315 muertes (87.26%) fueron consideradas de causa “obstétrica directa”, siendo las más frecuentes el aborto provocado (45%), la toxemia gravídica (17.7%), la sepsis posparto (15.8%) y las hemorragias obstétricas (5%). De causa “obstétrica indirecta” se clasificaron 19 casos (5.26%), señalándose como las más frecuentes las cardiopatías, el cáncer y las nefropatías. Se registraron, además, 27 casos de muerte “no obstétrica” (7.5%), acupando los primeros lugares la apendicitis, la neumonía y la meningitis.El 84% de las muertes fueron catalogadas como “evitables”, atribuyéndose su ocurrencia al factor paciente en el 67% de los casos, al factor médico en el 18% y el factor institucional en el 2%. El resto se debió a factores mixtos.Se pone de presente, como conclusiones, que la tasa de mortalidad encontrada es demasiado alta, tratándose de un hospital universitario. Sin embargo, al estudiar los factores implicados en las muertes se deduce que en éstas influyen más los aspectos social, cultural y económico, que el simplemente institucional. El aborto provocado, que ha tenido un auge alarmante, se encuentra involucrado en casi la mitad de las defunciones, en tanto que la toxemia gravídica y las hemorragias obstétricas han ido disminuyendo.Por último, se recomienda la creación de comités permanentes de mortalidad materna a nivel institucional, pues al tiempo que se constituyen en un mecanismo de auditoría médica, son un valioso instrumentó para identificar las causa; de muerte y los factores que constituyen a ésta. En esta forma se hace más fácil emprender medidas encaminadas a disminuir las defunciones ocurridas en la etapa grávido-puerperal.
Bieg z przeszkodami. Ambiwalencje sukcesu artystycznego w poszerzonym polu kultury
Authors: Stachura Krzysztof
Published: June 2020

Celem artykułu jest analiza ambiwalentnego charakteru kategorii sukcesu w świecie spo­łecznym artystów. W tekście przedstawiam znaczenia sukcesu z perspektywy twórców, osadzając nar­racje zogniskowane wokół sukcesu w kontekście przemian poszerzonego pola kultury. Wyjaśniam, ja­kie znaczenie ma transformacja pola kultury dla strategii adaptacyjnych stosowanych przez artystów. Odwołując się do prekarnych doświadczeń twórców, dokonuję rekonstrukcji sposobów zarządzania przez nich ich własnymi karierami. Bazując na zebranym materiale empirycznym, próbuję jednocześnie odpowiedzieć na pytanie o trudności i wątpliwości związane z osiąganiem sukcesu w środowisku ar­tystycznym oraz opisać uwarunkowania defensywno-kompensacyjnej strategii zarządzania sukcesem. W zakończeniu tekstu formułuję wnioski dotyczące sposobów hakowania przez artystów reguł gry zainstalowanych w poszerzonym polu kultury.
Strategie organizacji opieki nad dziećmi w społeczeństwie polskim w perspektywie nierówności społecznych
Authors: Suwada Katarzyna
Published: June 2020

Celem artykułu jest przyjrzenie się problematyce łączenia życia zawodowego z rodzicielstwem z perspektywy tak zwanej luki w opiece na dziećmi. Luka w opiece jest tutaj definiowana jako brak rozwiązań instytucjonalnych pozwalających na zapewnienie opieki nad małymi dziećmi. Analiza opiera się na badaniach jakościowych przeprowadzonych z polskimi rodzicami dzieci do lat ośmiu. Pokazuje ona, że rozwiązania instytucjonalne polskiej polityki rodzinnej wzmacniają nierówności płciowe i ekonomiczne. Horyzont możliwości zapewnienia opieki przez rodziców o niższych zasobach materialnych zasadniczo różni się od możliwości rodziców o wyższych zasobach. Kobiety mające niższe zasoby w obecnym systemie często są zmuszone do rezygnacji z pracy zawodowej, aby zapewnić opiekę. Natomiast w przypadku rodzin o średnich i wysokich zasobach strategią na zapewnienie opieki są żłobki i zatrudnianie niań. Analiza wskazuje również, że niezależnie od zasobów ekonomicznych, za opiekę przede wszystkim odpowiedzialne są matki.
Literatura y folklore en las leyendas post mortem del Cid
Authors: Boix Jovaní Alfonso
Published: June 2020

This article focuses on the critical analysis of posthumous legends of el Cid from a multidisciplinary heuristic approach by combining the study of its ancestral folkloric traces with the support of comparatistics in order to appreciate the literary and anthropological worth of these stories. A trip to the Great Beyond which will reach the end of the 19th century, when a legend with a clear Becquerian influence appeared, the analysis of which will allow us tounderstand this article as a research on medieval literature but, also, to frame it within the current trends of neomedievalism by analysing the transmission of medieval topoi and their current expression.
El ars poetria en el cine: repercusiones de la teoría de la amplificación de Geoffrey of Vinsauf en la narrativa audiovisual
Authors: Arriaga Benítez Juan Manuel
Published: June 2020

In this work it has been analized the participation of figures or techniques of amplification described by Geoffrey of Vinsauf, norman poet from 13th century, into the classical rhetoric dimensions known as dispositio (structure) and elocutio (style), so that I can exemplify how in film industry it can be witnessed its use in form of image design through cinematography, visual composition and scenic assembly. From this study, it is also possible to notice how screenwriters and directors have been able to offer moral or emotional meaning to the viewer.
Os Desafios da Medicina Física e de Reabilitação em Portugal Durante a Pandemia por COVID-19
Authors: Martins Cristiana Lopes , Rios Jonathan
Published: June 2020

N/a.
Information search trends about sharia: a comparation study between business-industry genre with book-literature genre
Authors: Wardhana Akhmad Kusuma
Published: June 2020

Indonesia has a large sharia market potential. This is because Indonesia has the largest Muslim population in the world. The market potential is supported by the openness of information via the internet. This study aims to observe trends in information search on the internet about sharia with comparative studies on the genre of "business-industry" with the genre of "book-literature". The approach in this research is descriptive qualitative with the method of a literature study to collect data. The primary data of this study are the trends in sharia information sought by internet users throughout 2019. The results of the study indicate that the trend of information about sharia with the "business-industry" genre is more than the "book-literature" genre. The trend of seeking information about halal is the most trend in both genres, while the trend of finding the least information is information about sharia research.
Parity of level neuron-specific enolase and a brain blood-groove at hemispheric ischemic stroke
Authors: Karyakina G. M. , Nadezhdina M. V. , Hinko M. A. , Gurariy N. M.
Published: June 2020

An inspection is conducted 60 patients with hemispheric ischemic stroke in age from 51 to 69 years, part on the degree of expressed of neurological deficit in obedience to the Scandinavian scale (19,0 ± 1,9) – I group (27), (41,1 ± 3,5) is II a group (33). The comparative analysis of neurological deficit is given, level neuron-specific enolase (NSE) in blood, hemodynamic indexes, character of atherosclerotic name-plates, exposed on the basis of ultrasonic duplex research of main arteries of cerebrum in a dynamics. Dependence is exposed between expressed of neurological defect, degree of damage of fabric of brain, characterized by the change of level of NSE and degree of disturbances of hemodynamic. Clear dependence is marked between a neurological defect and decline (p < 0,05) of high systole speed in a poststenotic area. Character of atherosclerotic name-plates reflected pathogenic of ischemic stroke.
The influence of the different direction physical tensions for heart rate variability of the sportsmen
Authors: Kudrya O. N.
Published: June 2020

During examining the heart rate variability a method of the spectral analysis was used. It was discovered that the spectral analysis indexes (ТР, HF, LF, VLF) of the highly qualified sportsmen depend on the training process direction. It was also revealed that VLF-spectral component is considered to be a condition of metabolic processes running in the sportsmen’s organisms and is linked with the formation and using the energy during physical tensions activity in an anaerobic conditions.
Efficiency of surgical treatment of multidrug-resistant Pulmonary Tuberculosis within the DOTS-PLUS program
Authors: Strelis A. K. , Strelis A. A. , Anastasov O. V. , Nekrasov Ye. V. , Raskoshnykh V. K. , Zadorozniy A. I. , Gubin Ye. A. , Schegertzov D. Yu. , Khristenko O. Yu. , Yanova G. V.
Published: June 2020

Efficiency of the surgical treatment of pulmonary tuberculosis for multidrug-resistant (MDR TB) tuberculosis patients was analyzed. Seventy DOTS-PLUS patients with various clinical forms of pulmonary tuberculosis and Mycobacterium resistance from 3 to 8 antituberculosis drugs have been operated. Positive clinical results have been achieved for 65 (92,8%) patients. Indications for surgical treatment for patients with MDR TB have been developed. To ensure positive outcomes of the surgical interventions, main objective is the development of so-called a favorable preoperative environment during the preoperative phase. It includes switching on intensive chemotherapy and pathogenetic methods of treatment.
Alcohol and premature death rates of the population of Tomsk Region
Authors: Kladov S. Yu. , Konobeyevskaya I. N. , Karpov R. S.
Published: June 2020

The role of the alcoholic factor in structure of death rate of the population of Tomsk area is studied. At pathology-anatomic research alcohol in blood was found out in 38,9% of cases. This parameter remains rather stable during of some years while death rate from a poisoning with ethyl spirit last three years has decreased almost on third. The given parameter speaks about essential underestimation of the alcoholic factor in structure of death rate. At carrying out of examinations and researches of corpses of nonviolent death ethyl spirit has been found out in 18,4%. These data draw attention to alchohol-dependent diseases of internal bodies. Other picture comes to light at the analysis of the alcoholic factor in structure of violent death rate. For 2007 at carrying out of examinations and researches of corpses of a violent death ethyl spirit has been found out in 63,2% of cases. The greatest contribution of the alcoholic factor is revealed at such reasons of death, as a poisoning with carbonic oxide (69,7%), action of low temperatures (67,4%), road and transport incidents (48,5%).
Characteristics of production cytokines in patients with development of chronic tick-borne borreliosis
Authors: Baraulina A. S. , Kologrivova Ye. N. , Zhukova O. B. , Chechina O. Ye.
Published: June 2020

For detection of cytokine production features in patients with development of chronic tick-borne borreliosis the evaluation of spontaneous, fitohaemagglutinin-stimulated and stimulated with antigen of borrelia cytokine production was conducted in supernatants of three-day blood cells cultures. High risk of development of chronic tick-borne borreliosis associated with intensive spontaneous and antigen-stimulated production of interferon-g and transforming growing factor-β1 in acute disease.
Antioxidant activity of thiophane in rats with of experimental tetrachlorolmethane-induced hepatitis
Authors: Smoliyakova V. I. , Plotnikov M. B. , Chernyshyova G. A. , Ivanov I. S. , Prosenko A. Ye. , Kandalintseva N. V.
Published: June 2020

The purpose of this investigation is to study antioxidant activity of sterically hindered phenol — thiophane in rats with toxical hepatitis. Increase of diene and triene conjugates as well as fluorescent products in hepar tissue was revealed. Course intragastric administration of thiophane decreased significantly the content of lipid peroxidation products (diene and triene conjugates, fluorescent products) and held over the α-tocopherol content in hepar tissue.
Morphological assessment of method of postresection pericardial defect closure using fabric implant on basis of nanostructural nikelide titanium fiber
Authors: Topolnitsky Ye. B. , Dambayev G. Ts. , Gyunther V. E. , Baikov A. N. , Khodorenko V. N. , Fomina T. I. , Shefer N. A.
Published: June 2020

Method of postresection pericardial defect closure using fabric implant on basis of nanostructural nikelide titanium fiber has been developed and tested on ten mongrels. Morphology of reclaim generated after pericardial reconstruction using fabric implant was studied. A new generated tissue has been shown to extend through implant and form single tissue reclaim, which keeps anatomico-physiological restoration of pericardial defect.
EXPERIMENTAL AND THEORETICAL FOUNDATIONS AND PRACTICAL IMPLEMENTATION OF TECHNOLOGY BRAIN-COMPUTER INTERFACE
Authors: Kaplan A. Ya. , Kochetova A. G. , Shishkin S. L. , Basyul I. A. , Ganin I. P. , Vasilev A. N. , Liburkina S. P.
Published: June 2020

Technology brain-computer interface (BCI) allow saperson to learn how to control external devices via thevoluntary regulation of own EEG directly from the brain without the involvement in the process of nerves and muscles. At the beginning the main goal of BCI was to replace or restore motor function to people disabled by neuromuscular disorders. Currently, the task of designing the BCI increased significantly, more capturing different aspects of life a healthy person. This article discusses the theoretical, experimental and technological base of BCI development and systematized critical fields of real implementation of these technologies.
INFLUENCE OF BIOFEEDBACK AND SELF-REGULATION PSYCHOTECHNIQUES ON THE COGNITIVE FUNCTIONS AND ALPHA ACTIVITY EEG
Authors: Bazanova O. M. , Vernon D. , Lazareva O. Yu. , Muravlyova K. B. , Skoraya M. V.
Published: June 2020

Comparison the influence of voluntary increasing alpha power and decreasing EMG by using biofeedback (BFB) and usual self-regulation techniques (SRT) on cognitive functions and alpha activity in 27 male subjects was provided. The results show that alpha-BFB improve cognitive task performance and enhance the alpha activity in participants with low alpha frequency. SRT without feedback has no such effect.
RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW
Authors: Krivonogov N. G. , Minin S. M. , Krylov A. L. , Lishmanov Yu. B.
Published: June 2020

The aim of this study were to develop a radionuclide method for quantitative estimation of the myocardial blood flow (MBF). Twelve patients with suspected coronary artery disease underwent both Tc-99mmethoxyisobutylisonitrile (MIBI) imaging and coronary arterial injection of Tc-99m-radioalbumin macroaggregates (MAA). The myocardial uptake and MBF obtained using radionuclide angiocardiography and relative distributions of Tc-99m-MIBI were compared with the obtained using whole body with MAA as the gold standard. The myocardial uptake and MBF measured by MIBI imaging showed a good linear correlation with the myocardial uptake and MBF measured by MAA. These results indicate that MBF may be estimated by Tc-99m-MIBI imaging and can be used for the early detection and estimation of the functional severity of coronary lesions.
SEARCH OF TUBERCULOSIS SUSCEPTIBILITY GENES USING THE RESULTS OF GENOME-WIDE ASSOCIATION STUDY OF CROHN’S DISEASE
Authors: Rudko A. A. , Freidin M. B. , Bragina Ye. Yu. , An A. R. , Puzyryov V. P.
Published: June 2020

Crohn’s disease (CD) and tuberculosis (TB) share several mechanisms of pathogenesis, and this suggests they also have common genetic susceptibility factors. To test this hypothesis, we performed the analysis of association between TB and polymorphisms of genes associated with CD, according to the results of genome-wide association studies, in Russians from Tomsk and indigenous people from Tuva. For the first time, The rs2872507 (ORMDL3), rs3810936 (TNFSF15), rs10192702 (ATG16L1), rs9286879 (1q24.3), rs10507523 (13q14.11) polymorphisms were found to be associated with TB in Russians. The rs1407308 (TNFSF15) and rs1736135 (21q21.1) were associated with the disease in Tuvinians. The associations found are likely due to the functional role of the relevant proteins and their pathogenetic influence on the immune reaction underlying tuberculosis infection. Overall, the study of polymorphisms associated with CD allowed us to identify new candidate genes for TB.
ANALYSIS OF EPIDEMIOLOGICAL INDICATORS OF TYPE 1 DIABETES ACCORDING TO THE REGISTER OF TOMSK AND TOMSK REGION
Authors: Samoilova Yu. G. , Novosyolova M. V. , Oleynik O. A.
Published: June 2020

Type 1 diabetes mellitus (T1DM) is a serious medical and social problem in the whole world. Despite the presence of a large amount of accumulated knowledge to control the disease, there are methodological limitations and uncertainties of the register. In order to obtain complete information on the prevalence and incidence of T1DM among children and adolescents in order to monitor the disease, providing diagnostic and rehabilitation measures, there was a need for analysis of epidemiological climate T1DM in children and adolescents of the Tomsk region. The evaluation found that T1DM on the rise, especially among young children, which raises the need for а personalized approach in addressing this issue.
ELECTROKINETIC PROPERTIES, IN VITRO DISSOLUTION, AND PROSPECTIVE HEMOAND BIOCOMPATIBILITY OF TITANIUM OXIDE AND OXYNITRIDE FILMS FOR CARDIOVASCULAR STENTS
Authors: Khlusov I. A. , Pichugin V. F. , Pustovalova A. A. , Konischev M. E. , Dzyuman A. N. , Epple M. , Ulbricht M. , Cicinskas E. , Gulaya V. S. , Vikhareva V. V.
Published: June 2020

A state of titanium oxide and oxynitride coatings on L316 steel has been studied before and after their contact with model biological fluids. Electrokinetic investigation in 1 mmol potassium chloride showed significant (more than 10 times) fall of magnitude of electrostatic potential of thin (200–300 nm) titanium films at pH changing in the range of 5–9 units during 2 h. Nevertheless, zeta-potential of all samples had negative charge under pH > 6.5. Long-term (5 weeks) contact of samples with simulated body fluid (SBF) promoted steel corrosion and titanium oxide and oxynitride films dissolution. On the other hand, sodium and chloride ions precipitation and sodium chloride crystals formation occurred on the samples. Of positive fact is an absence of calcification of tested artificial surfaces in conditions of long-term being in SBF solution. It is supposed decreasing hazard of fast thrombosis and loss of materials functional properties. According to in vitro experiment conducted, prospective biocompatibility of materials tested before and after their contact with SBF lines up following manner: Ti–O–N (1/3) > Ti–O–N (1/1), TiO2 > Steel. It may be explained by: 1) the corrosion-preventive properties of thin titanium oxide and oxynitride films;2) a store of surface negative charge for Ti–O–N (1/3) film; 3) minor augmentation of mass and thickness of titanium films connected with speed of mineralization processes on the interface of solution/solid body. At the same time, initial (before SBF contact) differences of samples wettability became equal. Modifying effect of model biological fluids on physicochemical characteristics of materials tested (roughness enhancement, a reduction or reversion of surface negative potential, sharp augmentation of surface hydrofilicity) should took into account under titanium oxide and oxynitride films formation and a forecast of their optimal biological properties as the materials for cardiovascular stents.
INFLUENCE OF RESISTIN ON THE COURSE OF ISCHEMIC HEART DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
Authors: Teplyakov A. T. , Akhmedov Sh. D. , Suslova T. Ye. , Andriyanova А. V. , Kuznetsova A. V. , Protopopova N. V. , Kalyuzhin V. V. , Nasanova O. N.
Published: June 2020

Relevance. Through dermal coronary intravascular revascularization by means of stenting is an effective method of treatment CHD patients with the type 2 diabets. At the same time frequency of stents restenosing for this special cohort of patients is fluctuating from 12 by 40 %.

Objective. To study prognostic significance of the new biomarker of intravascular inflammation of resisin in blood of CHD patients with DM 2 who suffered from stenting. Material and methods. In the study 60 patients (48 men and 12 women, in the middle age 60.9 years) with CHD and DM2 are included. The patients were divided into two groups: Patients with positive progress of comorbide pathology belonged to the first group (n = 30); in the second group (n =3 0) patients with unfavorable progress of cardiac vessel pathology were included. The further observation was carried during 12 months. Content of all the patients in blood of resistin with help of enzyme immunoassay analysis was determined, as well as lipid blood serum mixture and additional metabolic risk factors. By the indications control a coronary angiography was conducted. Restenosis of coronary arteries was counted as the narrowing of a coronal artery lumen of ≥70% in the place of an intervention.

The result. Unfavorable flow, including restenosis of coronary arteries was revealed in 30 cases (50%). ROC-analysis showed great predictive significance of resistin – (area under a curve >5/35, Sensitivity 86.2, Specificit 70.0) in development of constrictive coronary atherosclerosis restenosis of coronary arteries after their stenosis.

The conclusion. The study of resistin level in DM patients blood for the valuation of the disease prognosis and optimization of the tactics for choice of coronary pathology treatment seems expedient and informative.