bluuebunny/crossref_metadata_2025 huggingface dataset:
Impacts of the photo-driven post-depositional processing on snow nitrate and its isotopes at Summit, Greenland: a model-based study
Authors: Jiang Zhuang , Alexander Becky , Savarino Joel , Erbland Joseph , Geng Lei
Published: September 2021

Abstract. Atmospheric information embedded in ice-core nitrate is disturbed by
post-depositional processing. Here we used a layered snow photochemical column
model to explicitly investigate the effects of post-depositional processing on
snow nitrate and its isotopes (δ15N and Δ17O)
at Summit, Greenland, where post-depositional processing was thought to be
minimal due to the high snow accumulation rate. We found significant
redistribution of nitrate in the upper snowpack through photolysis, and up to
21 % of nitrate was lost and/or redistributed after deposition. The model
indicates post-depositional processing can reproduce much of the observed
δ15N seasonality, while seasonal variations in
δ15N of primary nitrate are needed to reconcile the timing of
the lowest seasonal δ15N. In contrast, post-depositional
processing can only induce less than 2.1 ‰ seasonal
Δ17O change, much smaller than the observation
(9 ‰) that is ultimately determined by seasonal differences in
nitrate formation pathway. Despite significant redistribution of snow nitrate
in the photic zone and the associated effects on δ15N
seasonality, the net annual effect of post-depositional processing is
relatively small, suggesting preservation of atmospheric signals at the annual
scale under the present Summit conditions. But at longer timescales when large
changes in snow accumulation rate occur this post-depositional processing
could become a major driver of the δ15N variability in ice-core nitrate.
Zorunlu Vatandaşlık Davranışı ile Presenteeism Arasındaki İlişkinin İncelenmesi
Authors: TELLİ DANIŞMAZ Açelya , BOZKURT Serdar , BAL Yasemin
Published: September 2021

The concept of compulsory citizenship behavior (CCB), described as the dark side of organizational citizenship behavior, has become a concept that organizations have recently begun to focus on with organizational behavior. Because compulsory citizenship behavior appears as a concept closely related to many results related to the employee and the organization. Presenteeism, which is expressed as continuing to come to work despite different physical and mental health problems, is another concept that is thought to be related to compulsory citizenship behavior. In this direction, the study's primary purpose is to examine the relationship between compulsory citizenship behavior and presenteeism. For this purpose, the data obtained from the questions asked in the form of an online questionnaire to 374 white-collar workers in various sectors in Turkey were analyzed through the SPSS program. As a result of the findings obtained from the analysis, it was seen that there was a moderate positive and significant relationship between compulsory citizenship behaviors and presenteeism. Key Words: Organizational Citizenship Behavior, Compulsory Citizenship Behavior, Presenteeism.
Metformin and Sildenafil Attenuate Inflammation and Suppress Apoptosis After Ischemia/Reperfusion Injuries in Rat Urinary Bladder
Authors: Park Jong Mok , Shin Ju Hyun , Yang Seung Woo , Lee Ji Yong , Lee Chung Lyul , Lim Jae Sung , Song Ki Hak , Kim Gun Hwa , Na Yong Gil
Published: September 2021

Purpose: Although metformin and sildenafil can protect various organs against ischemia/reperfusion (I/R) injuries, their effects and mechanisms of action in bladder I/R injuries remain unknown. This study investigated the effects and mechanisms of action of metformin and sildenafil against bladder I/R insults in rats.Methods: One hundred male Sprague-Dawley rats were randomly divided into 5 groups, each of which contained 20 rats: a sham-operated group, a bladder I/R group, and bladder I/R groups treated with metformin, sildenafil, or both agents. Ischemia was induced by clamping the bilateral common iliac arteries with atraumatic vascular clamps for 2 hours, followed by reperfusion for 7 days. During this period, rats were injected once daily with 4-mg/kg metformin and/or 1-mg/kg sildenafil.Results: I/R injuries induced increased malondialdehyde levels and myeloperoxidase activity and decreased superoxide dismutase activity. These changes were attenuated by treatment with metformin and/or sildenafil. The I/R group had significantly higher Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), Bax, caspase-3, and nuclear factor-kappa B (NF-κB) levels, and lower extracellular signal-regulated kinase, and Bcl-2 levels in the bladder than the sham-operated group; these changes were significantly ameliorated by metformin and/or sildenafil treatment. No differences in the levels of these markers were observed between rats coadministered metformin and sildenafil and those treated with either agent alone.Conclusions: Metformin and sildenafil protected the rat bladder against I/R injuries. This effect may have been due to the inhibition of reactive oxygen species production through MAPK, Bax, and Bcl-2 activation, and the restoration of inflammation through NF-κB inhibition. However, the combination of metformin and sildenafil was not more effective than either agent alone.
Consejos prácticos para el manejo de los jugadores con alineación incorrecta
Authors: Petersen Carl , Nittinger Nina
Published: September 2021

En el tenis, debido a que una mano se usa más que la otra y debido a la prevalencia hacía ciertos golpes como la derecha y el saque, se presta a desalineaciones que pueden generar tensión, debilidad, pérdida de potencia / fuerza e incluso lesiones. Este artículo presenta y discute el síndrome de alineación incorrecta y proporciona ejercicios para su evaluación y tratamiento.
Entrenamiento integrado aplicado en cancha - Estudios de casos ¿Es la metodología del futuro?
Authors: Unierzyski Piotr , Boguslawski Mieczyslaw , Wheatley Simon
Published: September 2021

Este documento discute el coaching integrado, un enfoque que se deriva de la teoría de que el desempeño experto se basa en los diferentes aspectos del juego (físico, psicológico, técnico y táctico) utilizados instintivamente y en conjunto por el atleta, y que por lo tanto la mejor manera de crear expertos habilidades y rendimiento es entrenar estos aspectos juntos. Se discuten ejemplos prácticos y casos de estudio.
Extensive enzymatic hydrolysates of whey and colostrum proteins for specialized food
Authors: Головач Татьяна Николаевна , Курченко Владимир Петрович , Асафов Владимир Александрович , Искакова Евгения Леонидовна , Танькова Нина Леонидовна
Published: September 2021

Проведено комплексное сравнительное исследование пептидного состава и биологических активностей глубоких ферментативных гидролизатов коровьего молока. Образцы гидролизованных сывороточных белков и молозива обладают подтвержденным антиоксидантным, антимутагенным и антибактериальным действием.

A comprehensive comparative study of peptide profile and bioactivities of extensive enzymatic dairy hydrolysates was carried out. Samples of hydrolysed whey proteins and colostrum possess proven antioxidant, antimutagenic and antibacterial effects.
Obtaining of new Bacillus subtilis-96 strain - a producer of proteolytic enzymes for the food industry
Authors: Костылева Елена Викторовна , Середа Анна Сергеевна , Великорецкая Ирина Александровна , Цурикова Нина Васильевна , Минеева Дария Тимуровна , Бобровенко Екатерина Юрьевна
Published: September 2021

В результате трех этапов индуцированного мутагенеза протеолитическая активность штамма B. subtilis st 18 № 359 была увеличена более чем в 2 раза с сохранением соотношения бациллолизина и субтилизина. Концентрированный препарат, полученный из культуральной жидкости нового мутантного штамма, показал высокую эффективность при гидролизе белков молочной сыворотки.

Three stages of induced mutagenesis resulted in more than 2 times increase of B. subtilis st 18 No. 359 proteolytic activity while maintaining the ratio of bacillolysin and subtilisin. The concentrated enzyme preparation obtained from the culture liquid of the new mutant strain has shown high efficiency during whey proteins hydrolysis.
Enzyme preparation with hydrolytic action to intensify the fermentation process
Authors: Принцева Анастасия Андреевна , Шарова Наталья Юрьевна
Published: September 2021

В работе представлены результаты исследований ферментного препарата гидролитического действия, обладающего инвертазной активностью, синтезируемого промышленным штаммом Aspergillus niger Л-4 - продуцентом лимонной кислоты, - в условиях глубинной ферментации гидролизата кукурузного крахмала, в технологии хлебопечения с целью интенсификации процесса брожения.

The paper presents the results of studies of the effect of an enzyme preparation of hydrolytic action with invertase activity, synthesized by the industrial strain Aspergillus niger L-4, a citric acid producer under conditions of deep fermentation of starch hydrolyzate, in baking technology in order to intensify the fermentation process.
Pengelolaan Sumberdaya Rawa Gambut Dengan Pertanian Sistem Vertikultur Di Desa Tanjung Taruna Kabupaten Pulang Pisau
Authors: Trianto Kevin Agus , Setiawan Wendi , Rindhianto Achmad Faried , Anggrieni Dewi , Yuptriani Shinta P. , Fahlifi Riza , Prasetyo Agung , Rizal Muhammad , Situmorang Josua , Rahmadini Dhea , Siahaan Enrico Rafael , Sumantri Deden Priyatna , Sinambela Megawati , Aprilyani Rossyta , Rahayuningsih Sri Endang Agustina
Published: September 2021

Desa Tanjung Taruna merupakan salah satu desa di wilayah Kecamatan Jabiren, Kabupaten Pulang Pisau, terletak di daerah dalam kawasan dataran rendah, kawasan rawa gambut dan daerah aliran sungai Kahayan. Kondisi pemukiman dengan model rumah panggung dibangun pada lahan sempit, tingkat pendidikan mayoritas SD-SMP dengan mata pencaharian umumnya penangkap ikan sehingga pengetahuan, keterampilan serta perekonomiannya masih perlu ditingkatkan melalui pelatihan dan pendampingan kegiatan Program Hibah Bina Desa (PHBD) ini bertujuan untuk memberikan pelatihan dan pendampingan guna meningkatkan pengetahuan, keterampilan dan kesejahteraan masyarakat. Metode kegiatan dilakukan dengan melakukan sosialisasi, pelatihan dan pendampingan tentang budidaya sayuran dan tanaman obat keluarga (TOGA) dengan sistem vertikultur sebagai alternatif solusi pertanian pada lahan sempit. Sistem vertikultur dilakukan dengan memanfaatkan kayu-kayu bekas, talang bekas untuk dijadikan tempat bertanam, pembuatan kompos organik. Hasil kegiatan menunjukkan partisipasi peserta cukup bagus dengan jumlah peserta sosialisasi sebanyak 35 orang dan peserta pelatihan sebanyak 38 orang. Berdasarkan hasil evaluasi diketahui bahwa peserta menjadi bertambah pengetahuan,keterampilan dan wawasan dalam memanfaatkan hijau yang tumbuh di rawa gambut menjadi kompos organik yang digunakan dalam budidaya sayuran dan toga sistem vertikultur dan dapat dijadikan tambahan penghasilan untuk dijual
Дослідження остеорегенераційної активності окістя нижньощелепних кісток, уражених кістами різного ґенезу
Authors: Мокрик Олег , Ломницький Ігор
Published: September 2021

In response to the prolonged increasing influence of the radicular cyst, there is an adaptive compensatory reaction of the adjacent bone tissue and periosteum located in the area of damage. However, in the available professional literature there is no data on the activity of the marker of osteoregeneration-alkaline phosphatase in the periosteum of the mandible, which is in the growth zone of osteoblastoclastoma. The purpose of the study: to study in a comparative aspect osteoregenerative activity of the periosteum of the mandibular bones affected by radicular cyst and cystic form of osteoblastoclastoma by using the histochemical method. Histochemical studies were performed in 10 patients with large radicular cysts (d>3.0 cm) located on the mandibles – 1st clinical group, and in 9 patients with cystic forms of osteoblastoclastomas, localized on the mandibles - 2nd clinical group. Determination of alkaline phosphatase in periosteal tissues of the mandible was performed by the method of simultaneous azo combination according to Kaplow. Prepared samples of histochemicals were studied under a light microscope, the received images were photographed. Digitized images of histochemicals were analyzed using the computer program ImageJ. The accumulation of alkaline phosphatase in the periosteum of the mandibular areas affected by osteoblastoclastomas is less intense compared to the process of synthesis of this enzyme in the periosteum of the mandible, which is affected by radicular cysts of large size. Osteoregenerative potential of periosteum of mandibular bones affected by radicular cysts is much greater than in the periosteum located in the growth zone of the cystic form of osteoblastoclastoma.
Asymmetric Cost Behavior Across Life Cycle Stages
Authors: Abdelhay Mohamed Abdelghany , Youssef Ahmed Mahmoud , Awad Mohamed Hamdy
Published: September 2021

The traditional model of cost behavior has been criticized for its symmetric cost behavior assumption. A new model has been proposed assuming that costs respond differently to upward and downward activity changes. The main objectives of this paper are to investigate the existence, degree, and nature of asymmetric cost behavior (ACB) phenomenon and examine how the organization life cycle (OLC) affects this phenomenon in the context of Egypt. The current study achieves these objectives by employing multiple regression to explore the behavior of cost of goods sold (COGS), selling, general and administrative cost (SGA), and total cost (TC) for 1577 firm-year observations (99 manufacturing firms) during the period from 2000 to 2019. The results demonstrate that all three cost proxies (COGS, SGA, and TC) are sticky with the highest degree of stickiness to TC. In addition, OLC is a conditional factor that affects how costs behave in response to change in activity level. Consistent with theoretical propositions, both COGS and TC exhibit anti-stickiness behavior for firms in the introduction stage and stickiness behavior for firms in the growth, mature, and shakeout/decline stages. However, SGA is only sticky for firms in the mature stage. However, the hypotheses related to asymmetric behavior of SGA were rejected for firms in the introduction, growth, and shakeout/decline stages.
APPLICATION OF DIRECT HYDROCARBON INDICATORS FOR OIL AND GAS PROSPECTING IN THE DNIPRO-DONETS DEPRESSION
Authors: VYZHVA Sergiy , SOLOVYOV Ihor , МYKHALEVYCH Ihor , KRUHLYK Viktoriia , LISNY Georgiy
Published: September 2021

Based on the results of numerous seismic studies carried out in the areas and fields of the Dnipro-Donets depression, the strategy to identify hydrocarbon traps in this region has been developed taking into account modern requirements for prospecting and exploration of gas and oil fields. The studies are designed to determine the favorable zones of hydrocarbon accumulations based on the analysis of the structural-tectonic model. A necessary element for solving such a problem is to aaply direct indicators of hydrocarbons to predict traps of the structural, lithological or combined type. It was determined that an effective approach to identify hydrocarbon traps in the region is attribute analysis employing seismic attributes such as seismic envelope, acoustic impedance or relative acoustic impedance. In most cases of practical importance, the analysis of the distribution of the values of these attributes turned out to be sufficient for performing the geological tasks. It is given an example of extracting additional useful information on the spatial distribution of hydrocarbon traps from volumetric images obtained from seismograms of common sources with a limited range of ray angles inclinations. To analyze the distributions of seismic attribute values, it is recommended to use the Geobody technology for detecting geological bodies as the most effective when using volumetric seismic data. The distributions of various properties of rocks, including zones of increased porosity or zones of presence of hydrocarbons are determined depending on the types of seismic attributes used in the analysis,. The use of several seismic attributes makes it possible to identify geological bodies saturated with hydrocarbons with increased porosity and the like.
The paper provides examples of hydrocarbon traps recognition in the areas and fields of the Dnipro-Donets depression practically proved by wells. A generalization on the distribution of promising hydrocarbon areas on the Northern flank of the Dnipro-Donets depression and the relationship of this distribution with the identified structural elements of the geological subsoil is made.
Pedro en la historia de Jesús según Marcos
Authors: Montes Peral Luis Ángel
Published: September 2021

Dos cuestiones cruciales trata de responder el Evangelio de Marcos: ¿quién es Jesús? y ¿qué significa ser discípulo suyo? Estas dos preguntas convergen, de modo paradigmático, en la persona, vocación y misión, o dicho de otro modo, en la historia de Pedro, el personaje más importante del escrito marquino después de Jesús. En el intencionado relato cristológico del evangelista comprobamos, y así lo exponemos de modo pormenorizado, cómo Pedro responde vitalmente a este reto, con sus luces y sus sombras, convirtiéndose en el modelo de referencia del ser discípulo de Jesús. Seguir el comportamiento de Pedro y asimilar todo aquello que es positivo en él, en las páginas vivas de esta singular obra, ayuda como nada a ser cristiano aquí y ahora.
El significado del término euaggelion en los comienzos del cristianismo
Authors: Guijarro Oporto Santiago
Published: September 2021

El término “evangelio” (griego: euaggelion) se ha estudiado en el marco de un modelo diacrónico que ha impedido percibir claramente los diversos significados que los primeros seguidores de Jesús dieron a esta palabra. A pesar de ello, los primeros escritos cristianos dan testimonio de que estos diversos sentidos coexistieron hasta mediados del siglo segundo. El presente estudio identifica dos trayectorias presentes en dichos escritos y propone una explicación de los significados que la palabra “evangelio” adquirió en ellos, observando que estos dos significados surgieron en dos contextos diversos (la tierra de Israel y la Diáspora), que determinaron la comprensión de esta palabra clave del sociolecto cristiano.
Filosofía política y ética social en los orígenes del cristianismo.
Authors: Ortega Cabrera Agustín
Published: September 2021

Este trabajo, en memoria agradecida de S. Vidal y partiendo de su obra con sus claves más relevantes, pretende presentar puntos y criterios para una filosofía política que, en relación con la ética social, puede ser fecundada por el cristianismo. Creemos que en la obra de S. Vidal, con sus estudios del Nuevo Testamento y orígenes del cristianismo, en especial de la figura de Jesús y Pablo, se encuentran unas claves o contenidos muy relevantes. Para exponer y profundizar en un pensamiento ético, con su inherente dimensión sociopolítica. Con una cosmovisión crítica, moral y liberadora, enraizada en el acontecimiento mesiánico de Jesús con su Reino y Pascua que nos trae la salvación, la paz y la justicia con una liberación integral.
Historia de la religión de Israel
Authors: Mielgo Constantino
Published: September 2021

La historia antigua de Israel ha sufrido un cambio profundo en los últimos 30 años del siglo pasado. Como la religión de Israel es histórica, ésta también tuvo que ser repensada radicalmente. No puede afirmarse desde luego el monoteísmo antiguo. La religión fue muy semejante a las de los pueblos vecinos. La crítica de las fuentes y los textos extrabíblicos, algunos muy interesantes, no permiten separar la religión de Israel de la de los otros pueblos. El politeísmo debió ser normal y corriente. Tampoco es creíble el aniconismo o ausencia de las imágenes de los dioses. Los descubrimientos arqueológicos confirman la existencia de diosas hasta bien entrado el siglo VI. A partir de este tiempo la reforma religiosa y social penetró con decisión en la sociedad israelita. El movimiento de Yahve sólo que arranca con el profeta Oseas fue el promotor de esta reforma. La limpieza fue profunda e impulsada por varias corrientes del judaísmo posexílico.
La caracterización de Jesús en las notas del narrador y su papel en el relato del cuarto evangelio
Authors: Hernández Carracedo José Manuel
Published: September 2021

El presente artículo expone las bases de un futuro estudio que analiza cómo el narrador caracteriza a Jesús en sus “notas” y cómo éstas ayudan a comprender adecuadamente la identidad de Jesús y sirven de guía para el lector en la lectura del relato. Para ello se ofrece una breve exposición de la historia de la investigación que se ha ocupado de los comentarios del narrador y se presenta, recurriendo a la teoría de la Polifonía y a la lingüística moderna, una metodología que permite definir e identificar los comentarios del narrador como notas dirigidas directamente al lector. El artículo se finaliza con un ejemplo de cómo estasnotas ayudan a la caracterización de Jesús a lo largo del relato.
Diagnostic and Prognostic Role of Cardiotrophin-1 in Patients with Heart Failure
Authors: Tokmachev Roman Evgenyevich , Budnevsky Andrey Valerievich , Podoprigora Alexander Vladimirovich , Chernik Tatiana Alexandrovna , Tokmachev Evgeny Viktorovich , Tikhomirova Alina Vasilievna
Published: September 2021

The review is devoted to the diagnostic and prognostic role of cardiotrophin-1 (CT-1) in patients with acute and chronic heart failure (CHF). The article provides information on the main regulatory effect of CT-1 in relation to the processes of cardiovascular remodeling. We considered the prospects of monitoring the plasma concentration of CT-1for the individualization of the assessment of cardiovascular risk in patients with CHF at various stages of the cardiovascular continuum. MeSH words: heart failure, cardiotrophin-1, hypertrophy, fibrosis, cytokines.
Correlation Between Point Shear Wave Elastography and Liver Function Tests as A Predictor of Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease
Authors: Saeed Rasul Shahla Mohammed , Salim Ali Khalaf , Hussein Hiwa Abubakr
Published: September 2021

Background: Nowadays, generating shear waves and simulation of the liver tissue is done using point shear-wave elastographic (pSWE) techniques which uess acoustic radiation force impulse (ARFI). Objective: This study aimed to evaluate the correlation between pSWE and liver function tests (LFTs) to predict liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). Materials and methods: It was a cross sectional study conducted in an Ultrasound Clinic in Suleymaniya city. The duration of the study was from 1st of November, 2018 to 30th of June, 2019 which conducted on 50 NAFLD patients. After confirming NAFLD diagnosis, the patients were referred to Ultrasound Clinic to go under pSWE test. Results: The data showed that the mean PSWE of NAFLD patient was 4.12±0.87 Kpa; and 18% of them had high PSWE (> 4.6). Elastography fibrosis score was distributed to F0 (82%), F1 (6%), F2 (8%) and F3 (4%). There was a significant association between high APRI and high Aspartate Aminotransferase/Alanine Aminotransferase(AST/ALT) ratio (p=0.04). There was also a highly significant association between elastography fibrosis score and APRI fibrosis score among NAFLD patients (p<0.001). Conclusion: This study showed that the pSWE is a valuable noninvasive diagnostic technique for predicting liver fibrosis among NAFLD patients and there is significant correlation between APRI and pSWE scores. Keywords: Non-alcoholic fatty liver disease, Point shears wave elastography, Liver fibrosis.
Carcinogenic and non-carcinogenic health risk assessment of air pollutant in a steel industry
Authors: Golbaghi Ameneh , Nematpour Leila , Damiri Zabiholah , Dehaghi Behzad Fouladi
Published: September 2021

Background: Chemical risk assessment is one of the major strategies that can help prioritize hazardous pollutants and decide on appropriate control measures. Objective: This study aim was evaluating carcinogenic and non-carcinogenic effects of chemical and fume compounds in a steel industry in South Iran. Methods: This study conducted in one of the steel industry with 1600 workers. After sampling the inhalation air of workers exposed to various chemicals, the method provided by risk assessment information system (RAIS) was used to assess cancer carcinogenic and non-Carcinogenic risk based on the findings. Results: Asbestos with the content of 1.5×10-10, chromium 1.36×10-2, and lead 5.38×10-5 definitive cancer and definite cancer are in the category of minor cancer effects, respectively. In calculating the non-cancer risk, the risk factor for Quotient Hazard Non-cancer (HQ) in hydrogen sulfide, chromium, and manganese were 3.08×102, 5.71×10-2, and 9.13×102 respectively, indicating non-cancer risk in them. Conclusion: Based on the values provided by the environmental protection agency, it is observed that some pollutants in the steel industry during the study period will increase the risk of cancer and non-cancerous diseases for steel industry workers. Therefore, considering appropriate engineering and management controls can help prevent these effects. Keywords: Carcinogenic risk, Chemical contaminants, Non-carcinogenic risk.
Effect of Pulley Therapy on Genurecurvatum in Children with Unilateral Cerebral Palsy: Randomized Controlled Trial
Authors: M. Hamouda Merhan , E. Mohamed Nanees , Abd el-Nabie Walaa A.
Published: September 2021

Objectives: Genu recurvatum commonly represents a more challenging problem that interferes with activities of daily living in children with cerebral palsy. This study aimed to investigate the effect of pulley therapy on genu recurvatum in children with unilateral cerebral palsy. Methods: Forty children with unilateral cerebral palsy aged from 3 to 6 years were randomly allocated into two equal groups: control group and study group. Both groups received designed physical therapy program in addition, study group received pulley therapy program instead of using free weights in control group for strengthening hamstring and tibialis anterior muscles. The program's protocol applied for one hour, three times per week for three successive months for each group. Degree of genu recurvatum was assessed pre- and post-treatment by using digital goniometer while, muscle strength of hamstring and tibialis anterior was assessed by using Lafayette manual muscle tester device. Results: Both groups showed significant improvement of all measured variables post treatment. The significant improvement after treatment in degree of genu recurvatum and muscle strength was obtained in favor to study group (p<0.05). Conclusions: Pulley therapy may be used within the rehabilitation program of children with unilateral cerebral palsy to treat genu recurvatum. Key words: Unilateral cerebral palsy, Hemiplegia, Genu recurvatum, Progressive resistance training, Pulley therapy.
BREACH OF PSYCHOLOGICAL CONTRACT AND QUALITY OF LIFE; PSYCHOSOMATIC STRAIN AS MEDIATOR AND POWER DISTANCE AS MODERATOR
Authors: Asad Muhammad
Published: September 2021

This study empirically examined the impact of breach of psychological contract on employees’ quality of life via the mediating mechanism of psychosomatic strain, while facilitating effect of power distance was also examined. Data were collected from a sample of 183 employees using a questionnaire. Results confirm that the breach of psychological contract declines employees’ quality of life, while mediating role of psychosomatic strain in this particular relationship was also established. Contrary to expectations, power distance does not act as a moderating variable. Implications, limitation and future research direction are discussed.
EXAMINING THE ROLE OF SUPPORT FOR CREATIVITY IN DETERMINING CREATIVITY; MEDIATING ROLE OF EPISTEMIC CURIOSITY AND MODERATING ROLE OF TRUST IN LEADERSHIP
Authors: Zafar Sarah
Published: September 2021

The current study examined the role of support for creativity in determining creativity with the mediating role of epistemic curiosity and moderating role of trust in leadership. Data were collected from 321 employees working in telecom sector of Pakistan situated in Rawalpindi, Islamabad, Sialkot and Lahore. Regression analysis suggested that support for creativity is positively associated with creativity and epistemic curiosity, whereas, there is a positive relationship between epistemic curiosity and creativity. Epistemic curiosity further mediates the relationship between support for creativity and creativity of employees, while trust in leadership moderates the relationship between Support for creativity and creativity of employees. Results are discussed in the light of existing environment in the private sector organizations of Pakistan. The paper concludes by discussing study limitations and future research directions.
DEFAULT RISK PREMIUM AND EQUITY RETURN OF NON-FINANCIAL COMPANIES OF PAKISTAN
Authors: Adalat Sadaf
Published: September 2021

The current study was aimed to examine the relationship between default risk premium and equity return by using sample of hundred companies from period between 2000 and 2015, listed at Karachi Stock Exchange. The firms are chosen on the basis of market capitalization. To examine the role of market premium, size premium, value premium and default premium in estimating the equity returns, the two pass regression was used. It was found that CAPM is valid model as market premium is priced but explanatory power is low. Similarly, the findings suggested that the CAPM model is not better than Fama and French model. Default risk premium is also significantly influencing equity returns. The study findings provided evidence about premium of default risk anomaly in Pakistani markets during the sample period. In default sorted portfolio the low default stocks earn lower than the high default stocks. This study has implications for decision markers in estimating cost of equity as well as weighted average cost of capital as it provides more information in comparison to CAPM. Moreover, information about premium of size, value and default anomaly may facilitate under developing investment strategies.
A Retrospective observational survey of adverse events following immunization comparing tolerability of covishield and covaxin vaccines in the real world
Authors: Rajpurohit Porus , Suva Manoj , Rajpurohit Hardik , Singh Yogesh , Boda Praveen
Published: September 2021

The COVID-19 vaccination drive is on a boost in India. On 16-January-2021 India has successfully driven the biggest vaccination drive for 300 million priority groups against the coronavirus disease (COVID-19) and rolled out the world's largest vaccination drive to vaccinate around. People were confused about which vaccination to choose and many were unaware of how these two vaccines differ from one other, while the government was working hard to build confidence and encourage people to come forward to take the made-in-India Covid-19 vaccine (COVAXIN and COVISHIELD). However, the result of the first phase and second phase vaccination drive clearly shows that both the Indian vaccines are effective and safe. Since, both the Indian vaccines have received Emergency Use Authorization  (EUA) by Drugs Controller General of India (DCGI) in India, the regulatory agency and the manufacturers are keeping a close watch and monitoring on the Adverse event reported following immunization (AEFI) and to allow quick identification and action of any new safety information. A retrospective observational cohort survey was conducted on 75 fully vaccinated volunteers. The data was collected and analyzed. The percentage of The AEFI experienced with COVISHIELD vs COVAXIN during 1st does was 92.45 % vs 77.27 % and with 2nd dose 86.79 % vs 72.72 % respectively. However, no SAE was reported during the survey and almost 20 % of subjects were aware of the AEFI reporting but because of negligence, didn't report. Fever was the most common AEFI experienced in both vaccines. Only 6.66 % of volunteers got an infection with COVID-19 post-vaccination.
ANALISIS SISTEM INFORMASI AKUNTANSI PENJUALAN PADA PT DAYA ANUGERAH MANDIRI MANADO
Authors: Bawimbang Vera , Tanor Linda , Suot Hennij Lenny
Published: September 2021

ABSTRAK
Penelitian ini bertujuan untuk mengetahui bagaimana sistem informasi akuntansi disebuah perusahaan. Penelitian ini dilakukan di PT. Daya Anugerah Mandiri Manado. Dalam penelitian ini digunakan jenis penelitian kualitatif dengan data diperoleh langsung melalui observasi dan wawancara langsung dengan pihak terkait. Dengan menggunakan teknik analisis data menurut  Miles dan Huberman, hasil penelitian ini ditujukan langsung pada proses penjualan yang sudah memakai system informasi. System informasi terkomputerisasi yang dipakai dalam perusahaan dimana system informasi yang digunakan menggunakan jaringan internet/online. Namun saat observasi langsung dilakukan membuktikan bahwa perusahaan belum bisa menjalankan sistem informasi akuntansi penjualan secara efektif dan efisien karena masih ada kendala jika jaringan sedang offline dan akan memberikan kesulitan bagi karyawan untuk menginput data dan pelaporan.
Kata Kunci: Sistem Informasi Akuntasi, Penjualan, Komputerisasi
 
ABSTRACT
               This research aims to find out how accounting information system in a company. This research was conducted at PT. Daya Anugerah Mandiri Manado. In this research, qualitative research type with data obtained directly through observation and direct interview with related parties. Using data analysis techniques according to Miles and Huberman, the results of this study are directed to the sales process that already uses the information system. Computering information system by using in a company, the system is network/online. In lived observation was showed the company can't operated the system by using effective and efficient. Therefore, the company was have problem when the network is offline and it was made staff has difficulty to process input and reported data.
 Keywords : System Information Accounting, Sale, Computering
PENGARUH SANKSI ADMINISTRASI PAJAK TERHADAP KEPATUHAN WAJIB PAJAK KENDARAAN BERMOTOR PADA KANTOR SAMSAT TOMOHON
Authors: Palit Rosari , Sumual Tinneke E. M. , Manengkey James
Published: September 2021

ABSTRAK
PeneIitian ini bertujuan untuk mengetahui apakah Pengaruh Sanksi Administrasi Pajak Terhadap Kepatuhan Wajib Pajak Kendaraan Bermotor Pada Kantor Bersama SAMSAT Kota Tomohon. Pendekatan yang dipakai pada penelitian ini merupakan pendekatan kuantitatif. SampeI dalam peneIitian ini adaIah 100 reponden. Metode yang digunakan untuk peneIitian ini yaitu metode survey dengan pendekatan kuantitatif. Dalam peneIitian ini data primer dengan dikumpulkan melalui teknik pengumpulan data wawancara, dan angket/kuesioner. Hasil penelitian ini menunjukan bahwa  sanksi administrasi pajak berpangaruh secara signifikan pada kepatuhan wajlb pajak dalam membayar pajak  kendaraan bermotor di Kantor Bersama SAMSAT Kota Tomohon
Keywords:Sanksi Administrasi Pajak, Kepatuhan Wajib Pajak Kendaraan Bermotor
ANALISIS SISTEM INFORMASI AKUNTANSI PEMBELIAN SUKU CADANG PADA PT HASJRAT ABADI TENDEAN MANADO
Authors: Ranti Grace , Kawatu Freddy Semuel , Bacilius Aprili
Published: September 2021

Abstrak
Penelitian ini bertujuan untuk mengetahui bagaimana sistem informasi akuntansi pembelian pada perusahan. Penelitian ini dilakukan pada PT Hasjrat Abadi Tendean Manado. Dalam penelitian ini mengunakan jenis penelitian kualitatif deskriptif, dengan data observasi langsung dan wawancara dengan pihak yang terkait. Hasil penelitian ini ditujukan langsung pada proses pembelian yang sudah memakai sistem informasi. Sistem informasi terkomputerisasi yang dipakai dalam perusahaan dimana sistem informasi yang digunakan menggunakan jaringan internet. Namun saat observasi langsung membuktikan bahwa sistem informasi akuntansi pembelian yang dilakukan pada PT Hasjrat Abadi Tendean Manado belum berjalan dengan efektif dan efisien karena masih ada kendala jika jaringan sedang error sehingga membuat karyawan  kesulitan  dalam penginputan data pada sistem.
 
Kata Kunci : Sistem Informasi Akuntansi, Pembelian, Komputering
 
 
Abstract
This study aims to determine how the purchasing accounting information system in the company.  This research was conducted at PT Hasjrat Abadi Tendean Manado.  This research uses descriptive qualitative research, with direct observation data and interviews with related parties. The results of this study are aimed directly at the purchasing process that is already uses information systems. Computerized information systems used in companies where the information system used uses the internet network. However, direct observation proves that the purchasing accounting information system carried out at PT Hasjrat Abadi Tendean Manado has not been effective and efficient because there are still problems if the network is an error, making it difficult for the employees  to input data into the system.
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Keywords : System Information Accounting, Purchasing, Computering
PENGARUH FAKTOR INDEPENDENSI AUDITOR DAN INTEGRITAS AUDITOR TERHADAP KUALITAS AUDIT PADA KANTOR INSPEKTORAT DAERAH PROVINSI SULAWESI UTARA
Authors: Kapo Jilly , Tanor Linda A.O , Sumual Frida M.
Published: September 2021

Abstrak
Tujuan dari penelitian ini untuk mengetahui pengaruh faktor independensi auditor dan integritas auditor tehadap kualitas audit di Kantor Inspektorat Daerah Provinsi Sulawesi Utara. Penelitian ini berlokasi di Kantor Inspektorat Daerah Provinsi Sulawesi Utara. Sampel dalam penelitian ini adalah seluruh karyawan audit. Jumlah sampel yang digunakan sebanyak 44 responden dengan menggunakan sampel jenuh. Penelitian ini menggunakan metode penelitian kuantitatif dengan metode survey, dan teknik pengumpulan data menggunakan kuesioner. Teknik analisis yang digunakan adalah analisis regresi linear berganda dan menggunakan SPSS 20. Hasil Penelitian menunjukkan bahwa faktor independensi auditor dan integritas auditor berpengaruh positif terhadap kualitas audit. Hal tersebut menggambarkan bahwa semakin tinggi tingkat independensi auditor dan integritas auditor di Kantor Inspektorat Daerah Provinsi Sulawesi Utara maka akan menghasilkan kualitas audit yang baik.
PERAN PERANGKAT DESA DALAM AKUNTABILITAS PENGELOLAAN DANA DESA
Authors: Rindorindo Sevtia , Tanor Linda A. O. , Pangkey Roy I. J.
Published: September 2021

Tujuan dari penelitian ini untuk mengetahui apakah perangkat desa desa di Desa Pakuweru sangat berperan dalam akuntabilitas pengelolaan dana desa. Metode penelitiannya adalah deskriptif kuantitatif. Hasil penelitian yang dilakukan bahwa peran perangkat desa dalam akuntabilitas pengelolaan dana desa adalah sangat berperan aktif kemudian pada perencanaan dana desa perangkat desa telah ikut berperan dalam menyusun perencanaan pembangunan desa sesuai hasil kesepakatan yang ada sehingga perangkat desa membuat Rencana Pembangunan Jangka Menengah Desa yang selanjutnya akan dibahas dalam musyawarah desa. Pelaporan dana desa dapat dilihat dari pelaporan realisasi Anggaran Pendapatan Belanja Daerah yang disampaikan dari kepala desa kepada bupati. Dalam pertanggungjawaban dana desa dapat dilihat dari rincian dana desa dari tahu 2016- 2019.
PENGARUH BOOK TAX DIFFERENCES DAN TINGKAT HUTANG TERHADAP PERSINTENSI LABA PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA 2016-2019
Authors: Maleong Jesinta Miralda Noralita , Tangkau Jaqueline , Kawulur Hisky
Published: September 2021

ABSTRAK
Persistensi laba ialah laba pada periode sekarang yang bisa dijadikan parameter untuk laba mendatang yang dapat dilihat dari perubahan laba setiap tahun. Riset ini dilaksanakan dengan tujuan guna mendapatkan bukti empiris terkait pengaruh book tax differences dan tingkat hutang terhadap persistensi laba pada entitas manufaktur yang tercatat di Bursa Efek Indonesia masa 2016-2019. Variabel book tax differences diproksikan dengan variabel perbedaan permanen dan perbedaan temporer. Riset ini menggunakan metode penelitian kuantitatif. Teknik purposive sampling dipakai untuk menentukan sampel dalam riset ini, maka  didapat 64 sampel dari 16 perusahaan. Metode analisis yang dipakai dalam riset ini ialah regresi data panel dengan memakai peranti lunak eviews 10. Hasil riset menemukan bahwa  variabel perbedaan permanen dan tingkat hutang tidak berpengaruh pada persistensi laba, sedangkan variabel perbedaan temporer berpengaruh pada persistensi laba. ketiga variabel mempunyai pengaruh secara serempak pada persistensi laba sebesar 9.78%.
Kata kunci: permanen, temporer, tingkat hutang, persistensi.
ABSTRACT
Profit persistence is the profit in the current period that can be a parameter for potential gains which can be seen from next year by the improvements in earnings. The purpose of this research was to obtain empirical evidence concerning the effect of book-tax differences and debt levels on the persistence of earnings in manufacturing entities listed on the Indonesian Stock Exchange for the period 2016-2019. The variable for book-tax differences is proxied by the variable for permanent difference and the temporary difference. This research used quantitative research methods. In this study, the purposeful sampling technique used to determine the sample and then obtained 64 samples from 16 firms. Panel data regression using Eviews 10 software is the analytical method used in this research. The results show that the permanent difference variable and the sum of the loan have no impact on earnings persistence, while the immediate difference variable does not affect earnings persistence. The three factors have a 9.78 percent simultaneous effect on earnings persistence.
Keywords: permanent, temporary, debt levels, persistence.
Pengaruh Income Smoothing Terhadap Earning Response Pada Perusahaan Manufaktur Sector Property, REAL ESTATE AND BUILDING CONSTRUCTION YANG TERDAFTAR PADA BEI TAHUN 2017-2019
Authors: Rori Audrey Natania , Tanor Linda , Kewo Cesilia
Published: September 2021

Penelitian ini bertujuan untuk menguji pengaruh income smoothing terhadap earning response. Yang menjadi sampel penelitian adalah perusahaan manufaktur sektor properti, real estate dan konstruksi bangunan yang terdaftar di BEI Tahun 2017-2019. Populasi penelitian sebanyak 58 perusahan, dimana menggunakan teknik purposive sampling dalam pengambilan sampel, sehingga sampel dalam penelitian menjadi 17 perusahaan dengan periode 3 tahun yaitu 2017-2019, maka total observasi menjadi 51. Penelitian ini merupakan penelitian kuantitatif dengan data sekunder, diperoleh dari laporan keuangan tahunan perusahan selama 3 periode, yang di ambil dari website www.idx.co.id dan www.yahoo.finance.co.id, selanjutnya mengumpulkan akun-akun yang berkaitan dengan variabel penelitian kemudian dihitung menggunakan rumus yang ada. Metode Analisis data yang digunakan adalah model regresi data panel, menggunakan bantuan program Eviews 9.0 untuk mengolah dan menganalisis data. Hasil penelitian ini menyimpulkan bahwa Income Smothing tidak berpengaruh terhadap Earning Response pada perusahan manufaktur sektor properti, real estate dan konstruksi bangunan yang terdaftar di BEI tahun 2017-2019.
Teaching and Assessing Problem Solving: An Example of an Incremental Approach to Using IRAC in Legal Education
Authors: Burton Kelley
Published: September 2021

Legal reasoning is a type of problem solving, and is situated within thinking skills, one of the six threshold learning outcomes established under the auspices of the Australian Learning and Teaching Council’s Bachelor of Laws Learning and Teaching Academic Standards Statement. The threshold learning outcomes define what law graduates are ‘expected to know, understand and be able to do as a result of learning’ (Kift et al., 2010, p. 9). The assessment of legal reasoning, and thus problem solving, should receive greater attention in legal education discourse (James, 2011, p. 15, James, 2012, p. 88). The dominant approach for problem-based questions in the discipline of law over the last 40 years is IRAC (issue, rule, application and conclusion). The acronym IRAC is not offensive and potentially instils a positive professional legal identity and is a student-centred approach to problem solving. This journal article documents an incremental approach to IRAC in law where first year students answer a problem-based law question using a grid format before preparing a barrister’s advice.
Reflexiones críticas sobre la experiencia obtenida de la aplicación de la propuesta didáctica «Aprendamos poesía por medio del foro»
Authors: Tórrez Daniela
Published: September 2021

En el siguiente ensayo abordaré las fortalezas y debilidades que se presentaron en el transcurso de las practicas con el grupo de noveno grado de c del colegio Boanerges Aragón Noli. ¿Quién diría que volvería a encontrarme a los mismos niños que un día me sacaron las canas verdes hace seis años, cuando con otro compañero y yo fuimos a organizar el día del maestro, convertidos ahora en adolescentes? Al parecer la vida es un pañuelo y son inesperadas las vueltas que da. A diferencia de la primera experiencia esta fue grata, aunque con sus altos y bajo concluyó de buena manera.
Antinociceptive activities with the possible mechanisms of action of hydroethanol leaf extract of Eclipta prostrata Hassk (Astraceae) in mice
Authors: Esther Oluwatoyin Agbaje  , Odunayo New Year Ashimolowo
Published: September 2021

Eclipta prostrata belongs to the family of plants known as Astraceae. It is a species of plant in the sunflower family, popularly known as "false daisy" in English. The whole plant contains the alkaloids nicotine and ecliptine; and used locally for treating bruises, cuts, wounds, liver disorders and pain, among others. This study investigated the analgesic activities of hydroethanolic leaf extract of Eclipta prostrata in rodents, using standard laboratory protocols. Doses of 50, 100, and 200 mg/kg were separately administered via oral route to the animals used in the various models - acetic acid-induced mouse writhing test, formalin - induced pain, hot plate-induced pain, and tail clip test. The effect of the extract was comparable to that produced by peripheral analgesics like aspirin and centrally acting analgesics like morphine used as positive control in the various models employed. The mechanism of action was elucidated through pre-treatment with naloxone (1 mg/kg), yohimbine (1mg/kg), ondasetron (0.2 mg/kg), atropine (2 mg/kg), glibenclamide (2 mg/kg). The extract activity was significant in all the models employed; however, it was more intense via the peripheral than the central pathway. Glibenclamide and atropine antagonized the activity of the decoction, which suggests that the herbal drug’s antinociceptive effect is mediated via potassium ion channel opening and cholinergic receptor. Phytochemical analysis of the leaf extract indicated the presence of flavonoids, phenols, alkaloids, phlobatanins, steroids, cardiac glycoside, and which probably contributed to the analgesic activity of the extract.
Chediak-Higashi Syndrome in Accelerated Phase, a Case Report
Authors: R Artriz
Published: September 2021

Chediak-Higashi syndrome corresponds to a series of genetic abnormalities in lysosomal transport, of autosomal recessive inheritance, characterized by partial oculocutaneous albinism and recurrent infections,1 usually between 7 and 10 years of age the accelerated phase of the disease, where developing hemophagocytic syndrome, given by a set of clinical findings, laboratory and histological studies where phagocytosis is prominent,2 with a failure in the regulation of the immune system due to an excessive production of pro-inflammatory cytokines that coexists with a dysfunction of natural killer cells and T lymphocytes, which leads to lethal development. We present a case of a 13-month-old patient, natural and from Pregonero, with a family history of consanguinity, recurrent respiratory infections, and a characteristic phenotype of Chediak-Higashi syndrome, without prior diagnosis or controls for this pathology, who presents with hemophagocytic syndrome leading to its death in 20 days.