bluuebunny/crossref_metadata_2025 huggingface dataset:
Ophthalmic complications in retinopathy of prematurity in the first decade of life in Korea using the national health insurance database
Authors: Hong Eun Hee , Shin Yong Un , Bae Gi Hwan , Choi Young Jin , Ahn Seong Joon , Kim Inah , Cho Heeyoon
Published: January 2022

The aim of this study is to investigate the epidemiology of ophthalmic complications of retinopathy of prematurity (ROP) after preterm birth using population-based database in South Korea. Using the National Health Insurance database, ophthalmic complications among premature infants born in 2007–2008 during their 10-year follow-up period were identified. Annual cumulative incidence rate and period prevalence of complications at each age were analyzed among those with ROP and those who underwent treatment for ROP (tROP). The hazard ratios (HRs) according to the presence of ROP and treatment for ROP were also analyzed. We identified 18,256 premature infants, 6995 of whom had ROP. The prevalence at 10th year for overall ophthalmic complications was 11.1% and 35.9% among ROP and tROP, respectively. Strabismus, amblyopia, and glaucoma were the three most common complications. The presence of ROP was associated with higher risk of complications (HR 1.53, 95%CI 1.44–1.61) among premature infants, and the presence of treatment for ROP was associated with higher risk of complications (HR 4.31, 95%CI 3.74–4.98) among ROP cases. This study reports the nationwide epidemiologic data on ophthalmic complications of ROP during the first decade of life, which will help advance our understandings and establish national strategies in managing ROP.
Adaptive transfer alignment method based on the observability analysis for airborne pod strapdown inertial navigation system
Authors: Chen Weina , Yang Zhong , Gu Shanshan , Wang Yizhi , Tang Yujuan
Published: January 2022

For the airborne pod strapdown inertial navigation system, it is necessary to use the host aircraft's inertial navigation system for the transfer alignment as quickly and accurately as possible in the flight process of the aircraft. The purpose of this paper is to propose an adaptive transfer alignment method based on the observability analysis for the strapdown inertial navigation system, which is able to meet the practical need of maintaining the navigation accuracy of the airborne pod. The observability of each state variable is obtained by observability analysis of system state variables. According to the weight of the observability, a transfer alignment filter algorithm based on adaptive adjustment factor is constructed to reduce the influence of weak observability state variables on the whole filter, which can improve the estimation accuracy of transfer alignment. Simulations and experiment tests of the airborne pod and the master strapdown inertial navigation systems show that the adaptive transfer alignment method based on the observability analysis can overcome the shortage of the weak observability state variables, so as to improve the alignment and the navigation performance in practical applications, thus improving the adaptability of the airborne pod.
Resting state functional connectivity provides mechanistic predictions of future changes in sedentary behavior
Authors: Morris Timothy P. , Kucyi Aaron , Anteraper Sheeba Arnold , Geddes Maiya Rachel , Nieto-Castañon Alfonso , Burzynska Agnieszka , Gothe Neha P. , Fanning Jason , Salerno Elizabeth A. , Whitfield-Gabrieli Susan , Hillman Charles H. , McAuley Edward , Kramer Arthur F.
Published: January 2022

Sedentary behaviors are increasing at the cost of millions of dollars spent in health care and productivity losses due to physical inactivity-related deaths worldwide. Understanding the mechanistic predictors of sedentary behaviors will improve future intervention development and precision medicine approaches. It has been posited that humans have an innate attraction towards effort minimization and that inhibitory control is required to overcome this prepotent disposition. Consequently, we hypothesized that individual differences in the functional connectivity of brain regions implicated in inhibitory control and physical effort decision making at the beginning of an exercise intervention in older adults would predict the change in time spent sedentary over the course of that intervention. In 143 healthy, low-active older adults participating in a 6-month aerobic exercise intervention (with three conditions: walking, dance, stretching), we aimed to use baseline neuroimaging (resting state functional connectivity of two a priori defined seed regions), and baseline accelerometer measures of time spent sedentary to predict future pre-post changes in objectively measured time spent sedentary in daily life over the 6-month intervention. Our results demonstrated that functional connectivity between (1) the anterior cingulate cortex and the supplementary motor area and (2) the right anterior insula and the left temporoparietal/temporooccipital junction, predicted changes in time spent sedentary in the walking group. Functional connectivity of these brain regions did not predict changes in time spent sedentary in the dance nor stretch and tone conditions, but baseline time spent sedentary was predictive in these conditions. Our results add important knowledge toward understanding mechanistic associations underlying complex out-of-session sedentary behaviors within a walking intervention setting in older adults.
The association of socio-economic and psychological factors with limitations in day-to-day activity over 7 years in newly diagnosed osteoarthritis patients
Authors: Kouraki Afroditi , Bast Tobias , Ferguson Eamonn , Valdes Ana M.
Published: January 2022

Previous research has established links between chronic pain and impaired cognitive ability, as well as between chronic pain and anxiety, in osteoarthritis. Furthermore, there is evidence linking risk of osteoarthritis to lower educational attainment. However, the inter-play of these factors with key social factors (e.g., social deprivation) at the early stages of osteoarthritis are not understood. Here, we used data from waves 4, 5, 6 and 7 of the Survey of Health, Ageing and Retirement in Europe (SHARE) (n = 971) and selected a subsample of respondents who initially did not report a diagnosis of osteoarthritis until wave 6. We used path models to test how social deprivation, education and anxiety, before diagnosis (waves 4 and 5), affect the relationship between cognitive ability, pain and limitations in activities of daily living following diagnosis (waves 6 and 7). We show that high social deprivation before diagnosis predicts greater limitations in activities of daily living after diagnosis, with this effect partly mediated by impaired cognitive ability. We also find that higher educational attainment before diagnosis may protect against limitations in activities of daily living after diagnosis via better cognitive ability and lower anxiety. Therefore, improving cognitive ability and managing anxiety may mitigate the associations of social deprivation and low educational attainment with limitations in activities of daily living.
Quantifying protein abundance on single cells using split-pool sequencing on DNA-barcoded antibodies for diagnostic applications
Authors: Sheng Jenny , Hod Eldad A. , Vlad George , Chavez Alejandro
Published: January 2022

Proteins play critical roles across all facets of biology, with their abundance frequently used as markers of cell identity and state. The most popular method for detecting proteins on single cells, flow cytometry, is limited by considerations of fluorescent spectral overlap. While mass cytometry (CyTOF) allows for the detection of upwards of 40 epitopes simultaneously, it requires local access to specialized instrumentation not commonly accessible to many laboratories. To overcome these limitations, we independently developed a method to quantify multiple protein targets on single cells without the need for specialty equipment other than access to widely available next generation sequencing (NGS) services. We demonstrate that this combinatorial indexing method compares favorably to traditional flow-cytometry, and allows over two dozen target proteins to be assayed at a time on single cells. To showcase the potential of the technique, we analyzed peripheral blood and bone marrow aspirates from human clinical samples, and identified pathogenic cellular subsets with high fidelity. The ease of use of this technique makes it a promising technology for high-throughput proteomics and for interrogating complex samples such as those from patients with leukemia.
High-throughput identification of genes influencing the competitive ability to obtain nutrients and performance of biocontrol in Pseudomonas putida JBC17
Authors: Dutta Swarnalee , Lee Yong Hoon
Published: January 2022

Elucidating underlying mechanisms of biocontrol agents (BCAs) could aid in selecting potent BCAs and increasing their biocontrol efficacy. Nutrient competition is an important biocontrol mechanism; however, essential nutrient sources, and contributing genes for nutrient competition still remain to be explored. Pseudomonas putida JBC17 (JBC17WT) suppressed green mold in satsuma mandarins by inhibiting conidial germination of Penicillium digitatum via nutrient competition. To analyze genes essential for biocontrol performance of JBC17WT, we generated a transposon (Tn)-mediated mutant library and selected mutants with the ability to suppress conidial germination. Several mutants in the genes of flagella-formation, including fliR, fliH, and flgG, increased biocontrol performance and enhanced inhibition of conidial germination. They lost swimming motility, exhibited increased growth and rapid carbon and nitrogen utilization than the wild type under nutrient-poor conditions. The nutrient competition assay using polytetrafluoroethylene cylinders revealed that conidial germination was inhibited by nutrient absorption under nutrient-poor conditions. In addition, genes, including amidohydrolase (ytcJ), tonB-dependent receptor (cirA), argininosuccinate synthase (argG), D-3-phosphoglycerate dehydrogenase (serA), and chaperone protein (dnaJ), were involved in the inhibition of conidial germination. The results of this study indicate that rapid and continuous absorption of nutrients by JBC17WT restrict nutrient availability for conidial germination on nutrient-limited fruit surfaces, thereby decreasing the chances of fungal spores infecting fruits. The high-throughput analysis of Tn mutants of this study highlighted the importance of nutrient competition and the genes that influence biocontrol ability, which contributes to the development of biocontrol applications.
A biogeographical study of red listed lichen species at temporal and spatial scales within protected and non-protected areas
Authors: Vicol Ioana , Mihăilescu Simona
Published: January 2022

The present study is focused on the temporal and spatial distribution of red listed lichen (RLL) species identified in both non-protected areas (NPAs) and protected areas (PAs) in Romania. This study revealed different scenarios of RLL based on two major patterns: (1) the fate of RLL before and after their designation in the red list in Romania and (2) the fate of RLL before and after the designation of PAs in Romania. Generally, the occurrences of RLL were well represented in time and space in both NPAs and PAs through geomorphological and biogeographical units. In particular, the occurrences of RLL were well represented, especially in hilly areas within PAs before and after their official designation, and this was an important aspect over a long period of time. Although NPAs were not less important regarding the occurrences of RLL species, it was observed that they followed the same pattern as PAs, namely, they were well represented in hilly areas and over a long period of time. The bioregions were significant for RLL species in both NPAs (continental and stepic) and PAs (continental, panonic, and stepic). As a significant finding of this study, NPAs and PAs should be subjected to an adequate conservation regime due to their biotical traditional heritage.
Effects of porous tantalum on periprosthetic bone remodeling around metaphyseal filling femoral stem: a multicenter, prospective, randomized controlled study
Authors: Motomura Goro , Mashima Naohiko , Imai Hiroshi , Sudo Akihiro , Hasegawa Masahiro , Yamada Harumoto , Morita Mitsuhiro , Mitsugi Naoto , Nakanishi Ryosuke , Nakashima Yasuharu
Published: January 2022

Periprosthetic bone loss due to adaptive bone remodeling is an important unresolved issue in cementless total hip arthroplasty (THA). The use of porous tantalum on the proximal surface of the femoral stem is expected to decrease postoperative bone loss around the prosthesis through early fixation. We conducted a multicenter randomized controlled study to determine if porous tantalum could reduce periprosthetic bone loss after THA. From October 2012 to September 2014, 118 patients (mean age, 61.5 years; 107 females and 11 males) were prospectively enrolled and were randomly allocated at a ratio of 1:1 to either a metaphyseal filling stem with a proximal porous tantalum coating (Trabecular Metal) or a conventional metaphyseal filling stem with fiber mesh coating (VerSys). Patients underwent dual-energy x-ray absorptiometry scans within 1 week after surgery (baseline) and at 6, 12, and 24 months after surgery to assess periprosthetic bone mineral density (BMD) in the 7 Gruen zones. In addition, the Japanese Orthopaedic Association hip score was assessed before surgery and at 6, 12, and 24 months after surgery. In the proximal periprosthetic region (zones 1 and 7), the Trabecular Metal group had significantly smaller reductions in BMD than the VerSys group throughout the study period. In the VerSys group, significant reductions in BMD compared to baseline were seen at each measurement point in all regions, except in zone 6 at 24 months. In the Trabecular Metal group, no significant reductions in BMD relative to baseline were seen in zones 1, 5, or 6 throughout the study period. Both groups demonstrated similar improvement in Japanese Orthopaedic Association hip scores over the study period. This study demonstrated that a proximally coated stem with porous tantalum has superior results over a conventional stem with titanium fiber mesh in terms of periprosthetic bone remodeling.
Plasmonic meniscus lenses
Authors: Riley Joseph Arnold , Healy Noel , Pacheco-Peña Victor
Published: January 2022

Controlling and manipulating the propagation of surface plasmons has become a field of intense research given their potential in a wide range of applications, such as plasmonic circuits, optical trapping, sensors, and lensing. In this communication, we exploit classical optics techniques to design and evaluate the performance of plasmonic lenses with meniscus-like geometries. To do this, we use an adapted lens maker equation that incorporates the effective medium concepts of surface plasmons polaritons travelling in dielectric-metal and dielectric-dielectric-metal configurations. The design process for such plasmonic meniscus lenses is detailed and two different plasmonic focusing structures are evaluated: a plasmonic lens with a quasi-planar output surface and a plasmonic meniscus lens having a convex-concave input–output surface, respectively. The structures are designed to have an effective focal length of 2λ0 at the visible wavelength of 633 nm. A performance comparison of the two plasmonic lenses is shown, demonstrating improvements to the power enhancement, with a 22% and 16.5% increase when using 2D (ideal) or 3D (realistic plasmonic) meniscus designs, respectively, compared to the power enhancement obtained with convex-planar lenses. It is also shown that the depth of focus of the focal spot presents a 19.8% decrease when using meniscus lenses in 2D and a 34.3% decrease when using the proposed 3D plasmonic meniscus designs. The broadband response of a plasmonic meniscus lens (550–750 nm wavelength range) is also studied along with the influence of potential fabrication errors on the generated effective focal length. The proposed plasmonic lenses could be exploited as alternative focusing devices for surface plasmons polaritons in applications such as sensing.
The optoelectronic properties improvement of double perovskites Cs2SnI6 by anionic doping (F−)
Authors: Wu Junsheng , Zhao Zhuo , Zhou Yanwen
Published: January 2022

Tin-based perovskite material is the best choice to replace heavy metal element lead during the last several years. Cs2SnI6 with Sn4+ is a fascinating optoelectronic material, which is a more air-stable composite cesium tin halide peroxide variant from CsSnI3. However, the optoelectronic performance between N and P type of Cs2SnI6 varies considerably. Herein, we synthesized uniform Cs2SnI6 by modified two-step method, which thermal evaporated CsI firstly, and followed annealing in the SnI4 and I2 vapor at 150 °C resulted in uniform Cs2SnI6 films. SnF4 is used as a dopant source to improve the optoelectronic properties of Cs2SnI6 films. Results indicate that good crystallinity was obtained for all films and the doped films underwent a crystalline plane meritocracy transition. The doped films had a flat, non-porous morphology with large grains. The high transmittance of the doped films in the infrared region led to the avoidance of self-generated thermal decomposition. With the help of F−, the films became more conductive and had higher carrier mobility. DFT calculations showed that doping with F reduced the surface energy of (004), resulted in a preferred orientation transition in the crystal of Cs2SnI6. Fluorine doped double layer perovskite materials would have a broader application prospect.
CCN2-induced lymphangiogenesis is mediated by the integrin αvβ5–ERK pathway and regulated by DUSP6
Authors: Hashiguchi Shiho , Tanaka Tomoko , Mano Ryosuke , Kondo Seiji , Kodama Shohta
Published: January 2022

Lymphangiogenesis is essential for the development of the lymphatic system and is important for physiological processes such as homeostasis, metabolism and immunity. Cellular communication network factor 2 (CCN2, also known as CTGF), is a modular and matricellular protein and a well-known angiogenic factor in physiological and pathological angiogenesis. However, its roles in lymphangiogenesis and intracellular signaling in lymphatic endothelial cells (LECs) remain unclear. Here, we investigated the effects of CCN2 on lymphangiogenesis. In in vivo Matrigel plug assays, exogenous CCN2 increased the number of Podoplanin-positive vessels. Subsequently, we found that CCN2 induced phosphorylation of ERK in primary cultured LECs, which was almost completely inhibited by the blockade of integrin αvβ5 and partially decreased by the blockade of integrin αvβ3. CCN2 promoted direct binding of ERK to dual-specific phosphatase 6 (DUSP6), which regulated the activation of excess ERK by dephosphorylating ERK. In vitro, CCN2 promoted tube formation in LECs, while suppression of Dusp6 further increased tube formation. In vivo, immunohistochemistry also detected ERK phosphorylation and DUSP6 expression in Podoplanin-positive cells on CCN2-supplemented Matrigel. These results indicated that CCN2 promotes lymphangiogenesis by enhancing integrin αvβ5-mediated phosphorylation of ERK and demonstrated that DUSP6 is a negative regulator of excessive lymphangiogenesis by CCN2.
Genome-wide perturbations of Alu expression and Alu-associated post-transcriptional regulations distinguish oligodendroglioma from other gliomas
Authors: Hwang Taeyoung , Kim Sojin , Chowdhury Tamrin , Yu Hyeon Jong , Kim Kyung-Min , Kang Ho , Won Jae-Kyung , Park Sung-Hye , Shin Joo Heon , Park Chul-Kee
Published: January 2022

Alu is a primate-specific repeat element in the human genome and has been increasingly appreciated as a regulatory element in many biological processes. But the appreciation of Alu has been limited in tumorigenesis, especially for brain tumor. To investigate the relevance of Alu to the gliomagenesis, we studied Alu element-associated post-transcriptional processes and the RNA expression of the element by performing RNA-seq for a total of 41 pairs of neurotypical and diverse glioma brain tissues. We find that A-to-I editing and circular RNA levels, as well as Alu RNA expression, are decreased overall in gliomas, compared to normal tissue. Interestingly, grade 2 oligodendrogliomas are least affected in A-to-I editing and circular RNA levels among gliomas, whereas they have a higher proportion of down-regulated Alu subfamilies, compared to the other gliomas. These findings collectively imply a unique pattern of Alu-associated transcriptomes in grade 2 oligodendroglioma, providing an insight to gliomagenesis from the perspective of an evolutionary genetic element.
Biophysics of Mouthfeel Perception
Authors: van Aken George A.
Published: January 2022

Mouthfeel experiences and ratings by consumers are related to the properties of the foods that generate these experiences, but the relationships are complex. This chapter describes our current understanding of the physiological mechanisms that link food textural descriptors of perceived mouthfeel to food properties by describing the underlying physiological links, starting with the mouthfeel described by the consumer and ending with the food structure and structure dynamics in the mouth. Each of these links sets limits to what can physiologically be transferred to the next step and each link is sensitive to the variations given by the feedback regulation of the higher physiological levels. The number of, and variability in, these links explains why tactile perception by consumers can be very different from instrumental measurements of structure and rheology.
Metabolic Impacts of Food Oral Processing
Authors: Forde Ciarán G. , Stieger Markus
Published: January 2022

The metabolic impact of oral processing is often overlooked in food design and when considering diet and lifestyle interventions to improve health and post-prandial metabolism. Food oral processing is the first step in the digestion and absorption of nutrients and informs a cascade of neuroendocrine and metabolic responses that occur post-ingestion. A food's physical, mechanical and lubricant properties inform how we adapt the duration and extent of oral processing during mastication, which, in turn, influences the incorporation of saliva and the surface area of the bolus. The properties of a food bolus at swallow can alter digestive kinetics and the rate and extent of post-prandial changes in the plasma concentrations of nutrients, in addition to the endocrine signals linked to feelings of satiety during the post-meal period. This chapter summarizes our current understanding of the metabolic impact of oral processing from acute feeding trials, long-term interventions and population-based studies. We focus on the impact of oral processing on post-prandial glucose and insulin responses, and energy intake and satiety, as they relate to body weight and metabolic health. We describe the impact of oral processing on gastric emptying and diet-induced thermogenesis. We provide an overview of the potential applications of these findings to food design and eating interventions that can be used to promote healthier diets and food intake behaviour. A better understanding of the metabolic impact of oral processing behaviour for specific consumer groups could assist in steering sensory perception, food choice and eating behaviour to promote healthier metabolic responses.
Oral Processing and Consumer Perception: Lipid-based Systems
Authors: Nicholson Reed A. , Gravelle Andrew J. , Baier Stefan K. , Marangoni Alejandro G.
Published: January 2022

Lipids affect the sensory properties and consumer perception of food materials throughout each stage of oral processing. The characteristics of the fat or oil droplets, along with the interactions between the droplets and the food matrix, influence the mechanical properties of the food experienced during first bite and comminution. The bulk properties of liquids, intact boluses and soft, semi-solid food materials depend on the lipid volume fraction, droplet size and droplet clustering. During the latter part of oral processing, sensory perception depends on the lubricating properties of the food material and wear characteristics within the mouth. Important factors determining the extent of lubrication and wear of oral surfaces include the lipid content and state, droplet characteristics and the propensity for these droplets to interact with saliva and to coalesce to form a coating on the oral surfaces. A fundamental knowledge of the effects of lipids throughout oral processing will enhance eating pleasure in lipid-based food systems.
Oral Processing of Chocolate Confectionary
Authors: He Q.
Published: January 2022

This chapter introduces the chocolate ingredients traditionally used in confectionary and chocolate manufacture and reviews the oral processing of chocolate and its relationship with chocolate sensory perception. When chocolate consumers first bite on a piece of chocolate, either with their incisors or molars, the hardness of the chocolate is sensed through the mechanoreceptors located in the oral cavity. After further chewing, the chocolate is broken down into smaller fragments. Stimulated saliva dissolves the sugar and the fat phase starts to melt. Mixing and shearing actions in the oral cavity emulsify the melted fat phase into the saliva phase. An oil-in-water emulsion stabilized with the surface-active ingredients from the chocolate formulation (e.g. milk proteins, cocoa solids and emulsifiers) is formed. Salivary protein also contributes to the stabilization of the oil–water interface. Over time, a chocolate bolus forms and a series of swallowing events follows once the chocolate boluses have developed favourable rheological properties. The swallowing action facilitates the perception of the chocolate flavour through retronasal olfaction. After swallowing, oil droplets can be retained in the oral cavity by adhering to the oral surface. The extent of this phenomenon is related to stability of the chocolate emulsion under oral conditions and contributes to the perception of mouthfeel.
Food Microstructures: Emulsions
Authors: Zaeim Davood , Wilde Peter J.
Published: January 2022

Emulsions are complex fluids, the flow and rheology of which are dictated not only by the rheology of their components, but also by the intricate colloidal interactions between the dispersed emulsion droplets. The behaviour of emulsions in the mouth is a complex, multifaceted process that is the net product of physical, textural and chemical stimuli from both the fat and the structures formed by the emulsion droplets. The physical processing of the emulsion in the mouth – including mixing, shear and the role of saliva – also affects the structure and stability of the emulsion. This chapter outlines the key aspects of emulsions that make them unique as food structures and the mechanisms underpinning their physicochemical behaviour, which may impact the sensory perception of fat. The complex physicochemical behaviour of emulsions is one of the reasons why engineering acceptable emulsion-based foods with reduced levels of fat is so challenging, but we discuss some of the main approaches that have been used to date.
Oral Processing of Low-Water Foods
Authors: Rosenthal Andrew J.
Published: January 2022

The sensation of moistness in food can be due to the presence of water and/or fat. The composition of foods may be plotted on the basis of their water and fat contents (both on a log, fat-free, dry-weight basis). This provides what is known as a moisture map. The third quadrant of this map represents foods that are low in water and low in fat. The well accepted Hutchings and Lillford breakdown path does not hold for foods in this third quadrant. Rather, after the gross structure is broken down, the comminuted material starts to adsorb saliva, causing it to thicken up, creating a de novo structure. This derived, secondary structure can enter the Hutchings and Lillford breakdown path and, with additional hydration and further mastication, may form a lubricated bolus suitable for swallowing.
Near-infrared Upconversion Nanomaterial-mediated Photothermal Conversion for Various Applications
Authors: Chu Zhaoyou , Chen Benjin , Wang Wanni , Chen Hao , Qian Haisheng
Published: January 2022

In this chapter, we have systematically summarized the research advances on the synthesis and applications of near-infrared upconversion nanostructures. Therefore, a brief introduction to the concept and the synthesis method of upconversion nanoparticles (UCNPs) is given first. Then, we put our emphasis on the construction of composite nanostructures comprised of upconversion nanoparticles and semiconductors, polymers, or dyes; demonstrating the principles of energy harvesting to enhance the photothermal conversion efficiency. As a result, near-infrared upconversion nanomaterial-mediated photothermal treatment, including for cancer therapy and antibacterial therapy, can be carried out under weaker light illumination. Thus it forms guidance for the synthesis and design of near-infrared upconversion composite nanostructures, which is very easy to follow and comprehend.
CO2as oxidant: an unusual light-assisted catalyst free oxidation of aldehydes to acids under mild conditions
Authors: Khan Shafiur Rehman , Saini Sandhya , Naresh K. , Kumari Alka , Aniya Vineet , Khatri Praveen K. , Ray Anjan , Jain Suman L.
Published: January 2022

A novel visible light-driven catalyst-free oxidation of aldehydes using CO2both in batch and flow photoreactors to get corresponding acids along with the formation of CO in the effluent gas is described.
Construction of Li3PO4 nanoshells for the improved electrochemical performance of a Ni-rich cathode material
Authors: Tao Xian-Sen , Sun Yong-Gang , Xu Yan-Song , Liu Yuan , Luo Jin-Min , Cao An-Min
Published: January 2022

A Li3PO4 nanocoating was successfully constructed via controlling the reaction between a nickel-rich cathode material and a preformed phosphorus-containing polymeric nanoshell, which contributes to much-improved electrochemical performance.
Control of supramolecular organizations by coordination bonding in tetrapyridylporphyrin thin films
Authors: Tomita Kazutaka , Shioya Nobutaka , Shimoaka Takafumi , Wakioka Masayuki , Hasegawa Takeshi
Published: January 2022

The edge-on and face-on orientations of tetrapyridylporphyrin are selectively obtained in a thin film by changing the central metal ion of the porphyrin ring.
A CuS- and BODIPY-loaded nanoscale covalent organic framework for synergetic photodynamic and photothermal therapy
Authors: Dong Xiao-Jie , Li Wen-Yan , Guan Qun , Li Yan-An , Dong Yu-Bin
Published: January 2022

A COF-based multifunctional nanomedicine CuS@COF-BDP, which can be used as a PTT/PDT bimodal therapeutic agent to inhibit cancer cell proliferation under visible- and NIR-II-light irradiation, is reported.
Bimetallic phosphide AlP/SiP2 composite as an anode material for lithium-ion batteries with long cycle life
Authors: Yu Jiale , Zhang Haiyan , Yang Changsheng , Xie Yiwen , Shen Junyao , Lin Yingxi , Zheng Cheng , Huang Haitao
Published: January 2022

The bimetallic phosphide AlP/SiP2@C composite delivers a superior electrochemical performance compared to that of the binary AlP@C and SiP2@C composites, owing to the advantages of the heterostructure and carbon layer protection.
Synthesis of syn- and enantioenriched anti-β-amino alcohols by highly diastereoselective borono-Mannich allylation reactions
Authors: Chevis Philip J. , Promchai Thanika , Richardson Christopher , Limtharakul Thunwadee , Pyne Stephen G.
Published: January 2022

A highly diastereoselective method for the synthesis of syn-β-amino alcohols and enantioenriched anti-β-amino alcohols has been developed involving α-hydroxyl aldehydes and chiral α-phenylaminoxyaldehydes or α-benzoyloxyaldehydes, respectively in Petasis borono-Mannich allylation reactions.
Electrochemical two-electron oxygen reduction reaction (ORR) induced aerobic oxidation of α-diazoesters
Authors: Ruan Mengyao , Chen Liang , Wen Ziyang , Yang Fan , Ma Chao , Lu Cuifen , Yang Guichun , Gao Meng
Published: January 2022

We present herein our recent progress in the oxidation of α-diazoesters to α-ketoesters by in situ generated hydrogen peroxide via a two-electron oxygen reduction approach.
Ir nanoclusters/porous N-doped carbon as a bifunctional electrocatalyst for hydrogen evolution and hydrazine oxidation reactions
Authors: Huang Hong-Li , Guan Xiya , Li Haibo , Li Ruiqing , Li Rui , Zeng Suyuan , Tao Shuo , Yao Qingxia , Chen Hongyan , Qu Konggang
Published: January 2022

Ir nanoclusters embedded in porous N-doped carbon were synthesized as superior bifunctional electrocatalysts for hydrogen evolution and hydrazine oxidation reactions, enabling energy-efficient hydrogen production.
Structurally rigidified cobalt bis(dicarbollide) derivatives, a chiral platform for labelling of biomolecules and new materials
Authors: El Anwar Suzan , Pazderová Lucia , Bavol Dmytro , Bakardjiev Mário , Růžičková Zdeňka , Horáček Ondřej , Fojt Lukáš , Kučera Radim , Grűner Bohumír
Published: January 2022

A reaction sequence for an easy coupling of the conformationally restrained cobalta bis(dicarbollide)(1−) ion with organic molecules is presented along with electrochemical studies and resolution of enantiomers.
Structure of the 5′ untranslated region in SARS-CoV-2 genome and its specific recognition by innate immune systemviathe human oligoadenylate synthase 1
Authors: Bignon Emmanuelle , Miclot Tom , Terenzi Alessio , Barone Giampaolo , Monari Antonio
Published: January 2022

The structure of the RNA SL1 of the 5′-untranslated region of SARS-CoV-2 genome is investigated. We also highlight the specific interactions of SL1 with OAS1 triggering the innate immune response.
Anomeric alkylations and acylations of unprotected mono- and disaccharides mediated by pyridoneimine in aqueous solutions
Authors: Dey Kalyan , Jayaraman Narayanaswamy
Published: January 2022

Pyridoneimine-mediated site-specific deprotonation of the hemiacetal moiety of several mono-, disaccharides in aq. solutions and the reactions of which with alkylating and acylating agents, leading to alkyl glycosides and sugar esters, is reported.
Synthesis and multifunctional sensing ability of axially chiral tetranuclear europium clusters
Authors: Cui Dongxu , Zhao Honglei , Kou Junning , Sun Chunyi , Wang Xinlong , Su Zhongmin
Published: January 2022

A pair of chiral tetranuclear europium clusters are synthesized and used for the detection of Fe3+ and nitro explosives.
Molecular solid solutions for advanced materials – homeomorphic or heteromorphic
Authors: Tsunashima Ryo
Published: January 2022

Crystalline molecular solid solutions are discussed on the basis of homeomorphism and heteromorphism of blended molecules.
Orientational isomerisation of guest molecules in equilibrium in a tubular host crystal formed via halogen and hydrogen bonding
Authors: Yamashita Yutaro , Tashiro Shohei , Shionoya Mitsuhiko
Published: January 2022

The orientation of the guest molecules in the one-dimensional tube is reversed in a temperature-dependent manner, and the ratio of the two orientational isomers changes continuously and reversibly from 100 : 0 to 0 : 100 in thermodynamic equilibrium.
Proton affinity and gas phase basicity of diamandoid molecules: diamantane to C131H116
Authors: Camacho-Mojica Dulce C. , Ha Jong-Kwon , Min Seung Kyu , Vianello Robert , Ruoff Rodney S.
Published: January 2022

Proton affinities and gas phase basicities are computed for diamantane (C14H20), triamantane (C18H24), ‘globular and planar’ isomers of tetramantane (C22H28) and pentamantane (C26H32), and for one ‘globular’ isomer of each of the larger diamondoids: C51H58, C78H72, C102H90, and C131H116.
Structural and energetic features of the dimerization of the main proteinase of SARS-CoV-2 using molecular dynamic simulations
Authors: Zhang Yunju , Zheng Liangzhen , Yang Yanmei , Qu Yuanyuan , Li Yong-Qiang , Zhao Mingwen , Mu Yuguang , Li Weifeng
Published: January 2022

Quantitative energy decomposition analysis of the main proteinase of SARS-CoV-2 revealed key residues that mediate the dimerization process. This provides important targets for the design of anti-SARS-CoV-2 drugs through inhibiting activity.
Deep-red to near-infrared luminescence from Eu2+-trapped exciton states in YSiO2N
Authors: Kitagawa Yuuki , Ueda Jumpei , Xu Jian , Nakanishi Takayuki , Takeda Takashi , Hirosaki Naoto , Tanabe Setsuhisa
Published: January 2022

Eu2+-Trapped exciton states in YSiO2N show anomalous deep-red to near-infrared luminescence under violet-blue light illumination.
Gating effect for gas adsorption in microporous materials—mechanisms and applications
Authors: Chen Kaifei , Mousavi Seyed Hesam , Singh Ranjeet , Snurr Randall Q. , Li Gang , Webley Paul A.
Published: January 2022

External stimuli or host–guest interactions induce structural changes, producing a gating effect in which an adsorbent suddenly becomes accessible to guest molecules. This effect greatly facilitates gas separation, storage, and molecular detection.
Bis(2-methoxyethyl)ether promoted intramolecular acceptorless dehydrogenative coupling to construct structurally diverse quinazolinones by molecular oxygen
Authors: Zhao Rongrong , Wen Simiaomiao , Fu Hao , Liu Mengna , Liu Qixing , Zhou Haifeng
Published: January 2022

A simple, efficient and clean intramolecular oxidative dehydrogenative coupling for the synthesis of dihydroisoquinolino[2,1-a]quinazolinones, 2-aryl quinazolinones, and analogues promoted by bis(2-methoxyethyl)ether/O2 has been achieved.
Study on spark discharge enhanced laser-induced breakdown spectroscopy of Fe particles in transformer oil
Authors: Yuan Huan , Ye Zhe , Wang Xiaohua , Liu Dingxin , Yang Aijun , Rong Mingzhe
Published: January 2022

In the quantitative analysis of Fe particles in oil, spark discharge can effectively enhance the LOQ of LIBS by three times. The enhancement and extraction of analysis lines can be realized by adjusting charging conditions appropriately.
A mesoporous ternary transition metal oxide nanoparticle composite for high-performance asymmetric supercapacitor devices with high specific energy
Authors: Deyab Nourhan M. , Taha Manar M. , Allam Nageh K.
Published: January 2022

We report on the optimized fabrication and electrochemical properties of ternary metal oxide (Ti–Mo–Ni–O) nanoparticles as electrochemical supercapacitor electrode materials.
Integrated therapy platform of exosomal system: hybrid inorganic/organic nanoparticles with exosomes for cancer treatment
Authors: Chan Ming-Hsien , Chang Zhi-Xuan , Huang Chi-Ying F. , Lee L. James , Liu Ru-Shi , Hsiao Michael
Published: January 2022

Hybrid inorganic/organic nanoparticles with exosomes can be applied as a novel platform for drug delivery systems. This biomimetic nanoplatform combines the functions of natural biomaterials to efficiently carry drugs to the center of cancer cells.
In situ synthesis of advantageously united copper stannate nanoparticles for a new high powered supercapacitor electrode
Authors: Farahpour Mona , Arvand Majid
Published: January 2022

A novel CuNi2O4@SnS@rGO/NF multicomponent hybrid material leads to fast ion/electron transfers at the electrode/electrolyte interface.
Regioselective direct sulfenylation of glycals using arylsulfonyl chlorides in the presence of triphenylphosphine: access to C2-thioaryl glycosides
Authors: Kumar Harikesh , Dubey Atul , Prajapati Gurudayal , Kant Ruchir , Ampapathi Ravi S. , Mandal Pintu Kumar
Published: January 2022

Cheap and easily available arylsulfonyl chlorides as a sulfur source reductively couple with glycals in the presence of triphenylphosphine to afford C2-thioaryl glycosides.
A low-cost and facile electrochemical sensor for the trace-level recognition of flutamide in biofluids using large-area bimetallic NiCo2O4 micro flowers
Authors: Durai Lignesh , Gopalakrishnan Arthi , Badhulika Sushmee
Published: January 2022

Nickel–cobalt-based bimetallic oxide compound (NiCo2O4) as a highly sensitive and selective platform for the detection of flutamide in biological fluids.
Mercaptosilane-assisted synthesis of highly dispersed and stable Pt nanoparticles on HL zeolites for enhancing hydroisomerization of n-hexane
Authors: Wang Jinshan , Liu Cun , Zhu Peng , Liu Haiou , Zhang Xiongfu
Published: January 2022

Pt/HL-SH catalysts were synthesized by a facile mercaptosilane-assisted in situ synthesis approach and exhibited better catalytic performance in n-hexane hydroisomerization.
Cleaner technology for the production of linear long-chain α-olefins through a “millisecond” oxidative cracking process: a positive impact of the reactant carbon chain length
Authors: Cruchade Hugo , Pouilloux Y. , Beauchet R. , Pinard Ludovic
Published: January 2022

The oxidative cracking ofn-decane,n-dodecane,n-tetradecane andn-hexadecane was assessed at millisecond contact times on a platinum catalyst at a C/O molar ratio of 1.8.
Advanced composite glasses with metallic, perovskite, and two-dimensional nanocrystals for optoelectronic and photonic applications
Authors: Konidakis I. , Karagiannaki A. , Stratakis E.
Published: January 2022

Reviewing the development of advanced composite glasses with metallic, perovskite, and two-dimensional nanocrystals for optoelectronic and photonic applications.
Tannic acid-polypyrrole multifunctional coating layer enhancing the interface effect and efficient Li-ion transport of a phosphorus anode
Authors: Li Xu , Han Xinpeng , Liu Runze , Zhang Shaojie , Zhang Yiming , Cao Yu , Wang Xiaoyi , Wang Ruying , Yang Zhanxu , Sun Jie
Published: January 2022

A tannic-polypyrrole (TA-PPy) coating layer around a phosphorus-nanotube (P-CNT) electrode boosts electronic and ionic transfer, resulting in good high-rate performance and reduced volumetric expansion for lithium-ion batteries.
A self-assembling nanoparticle vaccine targeting the conserved epitope of influenza virus hemagglutinin stem elicits a cross-protective immune response
Authors: Qiao Yongbo , Li Shuang , Jin Shenghui , Pan Yi , Shi Yuhua , Kong Wei , Shan Yaming
Published: January 2022

A schematic overview showing nanoparticle preparation, BALB/c mice immunization, and viral challenge. Humoral and cellular immune responses were determined after three immunizations, and protective effects were evaluated after the challenge.
Self-assembled transition metal chalcogenides@CoAl-LDH 2D/2D heterostructures with enhanced photoactivity for hydrogen evolution
Authors: Peng Linfen , Yu Changqiang , Ma Yuheng , Xie Guanshun , Xie Xiuqiang , Wu Zhenjun , Zhang Nan
Published: January 2022

Electrostatic self-assembly offered an effective and universal strategy for innovatively constructing a class of CoAl-LDH/transition metal chalcogenides 2D/2D heterojunctions for boosted photocatalytic H2 evolution.
Size and surface-energy dependence of the adsorption/desorption equilibrium in ethanol electro-oxidation by Pd-nanoparticles. Theory and experiment
Authors: Maya-Cornejo J. , Hernández S. I. , Estévez Miriam , Santamaría-Holek I.
Published: January 2022

The current–voltage relation of ethanol electro-oxidation by Pd nanoparticles depends on their radius, the temperature and electron-transfer coefficient, the adsorption equilibrium constant, the surface energy, and the number of active surface sites.
Synthesis and characterisation of heteroatom-doped reduced graphene oxide/bismuth oxide nanocomposites and their application as photoanodes in DSSCs
Authors: Ngidi Nonjabulo P. D. , Muchuweni Edigar , Nyamori Vincent O.
Published: January 2022

Semiconductor materials have been employed in photovoltaic devices to solve several global issues, especially the energy crisis emanating from the depletion and hazardous nature of conventional energy sources, such as fossil fuels and nuclear energy.
A high-energy efficiency static membrane-free zinc–bromine battery enabled by a high concentration hybrid electrolyte
Authors: Liu Siyang , Wu Jing , Huang Jiaqi , Chi Xiaowei , Yang Jianhua , Liu Yu
Published: January 2022

A high concentration ZnBr2with LiCl electrolyte inhibits the cross diffusion of bromine and avoids the corrosion and dendrite problems of the zinc anode, thus realizing a high efficiency static membrane-free zinc–bromine battery.
Elucidating the roles of acid site nature and strength in the direct conversion of levulinic acid into ethyl valerate: the case of Zr-modified beta zeolite-supported Pd catalysts
Authors: Muñoz-Olasagasti M. , Martínez-Salazar I. , Granados M. López , López-Aguado C. , Iglesias J. , Morales G. , Mariscal R.
Published: January 2022

The strong Brønsted and Lewis acid sites are active in the tandem conversion of levulinic acid into ethyl valerate. The intrinsic activity of the former is more significant and the Pd/HBEA catalyst deactivation is partially reversible by calcination.
Hydrovoltaic power generation from multiwalled carbon nanotubes
Authors: Kumar Rahul , Tabrizizadeh Tina , Chaurasia Sumit , Liu Guojun , Stamplecoskie Kevin
Published: January 2022

The hydrovoltaic effect, which is a voltage generated at the interface of water with polarizable materials, is an exciting new frontier for environmentally friendly electrical power generation.
Layered MAX phase electrocatalyst activity is driven by only a few hot spots
Authors: Novčić Katarina A. , Iffelsberger Christian , Pumera Martin
Published: January 2022

The microscopic analysis of the MAX phase microparticles shows that the electrochemical activity of the microparticles is driven by a few particles with an outstanding catalytic activity towards hydrogen evolution.
Polyoxometalate–covalent organic framework hybrid materials for pH-responsive photothermal tumor therapy
Authors: Wang Wenxin , Song Yuting , Chen Jiayi , Yang Yanyan , Wang Jiawei , Song Yan , Ni Jiatong , Tang Minglu , Zhao Junge , Sun Yuan , Sun Tiedong , Peng Jinsong
Published: January 2022

HPB@COF nanoparticles were synthesized in situ using a one-pot method, and exhibited excellent pH-responsive release properties and photothermal tumor treatment effects.
Boosting organic afterglow efficiency via triplet–triplet annihilation and thermally-activated delayed fluorescence
Authors: Zhang Jiulong , Li Jiuyang , Li Xun , Yuan Shou , Sun Yan , Zou Yunlong , Pan Yingtong , Zhang Kaka
Published: January 2022

TTA and TADF mechanisms with moderate rate constants on the order of 10−1 to 101 s−1 have been incorporated into dopant–matrix systems to significantly enhance the organic afterglow efficiency under ambient conditions.
Experimental evaluation of indium(i) iodide as a lead-free perovskite-inspired material for photovoltaic applications
Authors: Ustinova Marina I. , Babenko Sergey D. , Luchkin Sergey Yu. , Talalaev Filipp S. , Anokhin Denis V. , Olthof Selina , Troshin Pavel A.
Published: January 2022

Low structural dimensionality and the anisotropy of carrier transport in In I films are the main reasons why they show modest performances in solar cells (PCE = 1%) but demonstrate high photodetectivity (>103) in lateral photodetectors.
Correction: Reversible electrowetting transitions on superhydrophobic surfaces
Authors: Vanzo D. , Luzar A. , Bratko D.
Published: January 2022

Correction for ‘Reversible electrowetting transitions on superhydrophobic surfaces’ by D. Vanzo et al., Phys. Chem. Chem. Phys., 2021, 23, 27005–27013, DOI:10.1039/D1CP04220C.
Construction of chevaux-de-frise from cellulose nanocrystals to enable mechano-bactericidal activity on recycled waste cotton films
Authors: Zhou Chufan , Girouard François , O'Brien Bridget , Ronholm Jennifer , Wang Yixiang
Published: January 2022

The chevaux-de-frise-like nanostructure formed by CNC “needles” deposited on RC films through vacuum filtration can mechanically eliminate foodborne bacteria.
Correction: A graphene hybrid supramolecular hydrogel with high stretchability, self-healable and photothermally responsive properties for wound healing
Authors: Zhang Haifeng , Zheng Shiya , Chen Canwen , Zhang Dagan
Published: January 2022

Correction for ‘A graphene hybrid supramolecular hydrogel with high stretchability, self-healable and photothermally responsive properties for wound healing’ by Haifeng Zhang et al., RSC Adv., 2021, 11, 6367–6373, DOI: 10.1039/d0ra09106e.