bluuebunny/crossref_metadata_2025 huggingface dataset:
Biochemical aspects of KB-28 compound on physically loaded study subjects
Authors: Toziuk Olena , Krasna Olga , Kryvoviaz Olena , Rodinkova Victoria , Melnyk Andrii , Ivko Tanya , Voronkina Alona , Hutsol Viktoriia
Published: October 2019

In previous studies of actoprotective activity of 5-R-thio-tetrazolo[1,5]quinazoline derivatives in normal and complicated experimental conditions, sodium 2-(tetrazolo [1,5-c]quinazoline-5-ylthio)acetate (KB-28) was found to be the leader of the experiment. The objective of the current study was to characterize the effects of KB-28 compounds on carbohydrate and lipid exchange indices under the conditions of physical load as a possible mechanism of actoprotective effect. In the course of the experiment, the indices of carbohydrate and lipid exchange in the muscle, blood and liver of animal models were determined following a 15-day physical load course. In doing so, glucose, glycogen and total lipid concentrations were assessed. The KB-28 compound was administered daily at levels determined during the course of regular physical load normalized metabolic processes in rats. The results were then compared to a control which received intraperitoneally the equivolume 0.9% sodium chloride solution. The phenomenon of actoprotection consisted in enhancing concentrations of glycogen in skeletal muscles and liver. Compared to the control figures, this increase was 28.8% and 25.0%, accordingly. Moreover, the course of KB-28 caused a statistically significant reduction (by 32.1%) of the total serum lipid concentration in the animals under physical load. The effect may be a sign of the ability of this substance to utilize active lipolysis for improvement of the skeletal muscle performance. Having analyzed the results obtained, we can draw a conclusion that influencing the biochemical processes in the study models is one of the mechanisms of the KB-28 actoprotective effect.
Trilobite assemblage of Calceola-bearing beds in Acanthopyge Limestone (Choteč formation, Middle Devonian, Eifelian, Prague Basin, the Czech Republic)
Authors: Budil Petr , Mergl Michal
Published: October 2019

The trilobite assemblage of Calceola-bearing beds in the upper part of Acanthopyge Limestone (Choteč Formation, Eifelian) in the Koněprusy area, the Czech Republic, is described. Together with occurrence of Calceola, it indicates absence of significant palaeogeographic barriers restricting the distribution of the Rhenish-Type faunas in the Middle Devonian. The generic composition of the gathered trilobite assemblage somewhat differs from typical Acanthopyge-Phaetonellus assemblage characteristic for the Acanthopyge Limestone facies in possible absence and/or very rare occurrence of Phaetonellus, and only infrequent occurrence of Acanthopyge. Phacopid Chotecops cf. hoseri (Hawle et Corda, 1847) distinctly dominates; all other taxa are rather rare. Important is an occurrence of scutelluids of the Scutellum sensu lato group (preservation of remains does not enable more precise determination) and Longiproetus(?). Trilobite remnants are generally poorly preserved and very fragmented (only minute shields are not affected), which support a high-dynamic, shallow-water original environment.
Predictors of No-Reflow Phenomenon: Diabetes Mellitus type II and Obesity and their Associated Mortality in Stemi Patients after Primary PCI
Authors: Pantea-Roșan Larisa Renata , Ţica Otilia Anca , Moisi Mădălina , Pantea Vlad Alin , Ţica Ovidiu , Vesa Cosmin , Babeș Katalin , Popoviciu Mihaela , Popescu Mircea Ioachim
Published: October 2019

The prognosis of STEMI patients experiencing the no-reflow phenomenon is unfavorable both in the short- and long-term compared to patients who do not develop this pathology, and it is even worse as other cardiovascular risk factors There is a correlation between the no-reflow phenomenon and diabetes mellitus type II and obesity and this conditions represent stong predictors of mortality.
Gave Syndrome – A Rare and Mysterious Cause of Gastrointestinal Hemorrhage in the Elderly
Authors: Simache Alina , Bălăceanu Alice , Voiculeţ Cornelia , Omer Secil , Dina Ion , Zaharia Magda Ruxandra
Published: October 2019

GAVE syndrome (gastric antral vascular ectasia) is a rare cause of gastrointestinal bleeding. It affects mainly the elderly. The syndrome was named “watermelon stomach” because of its typical endoscopic appearance of “watermelon stripes” observed at the gastric antral level. We present the case of an 80-year-old female patient, under iron substitution therapy for an iron deficiency anemia previously diagnosed. The woman was admitted to our hospital for non-specific symptoms, severe asthenia and postural instability. The clinical examination noted pallor of skin and sclera, without hematemesis or melena. Paraclinical tests revealed severe hypochromic microcytic anemia and hyposideremia, with a positive fecal occult blood test. Because the patient was refractory to the iron therapy, presenting with severe anemia, which required blood transfusions, we suspected a diagnosis of acute hemorrhagic gastritis. In order to reveal the source of the hemorrhage, an upper gastrointestinal endoscopy was performed, which described the typical appearance of prominent, tortuous, erythematous streaks traversing the antrum and converging toward the pylorus, creating the “watermelon stripes” pattern, with lesions that bleed easily during the biopsy process. In a different endoscopic session, the argon plasma coagulation treatment was applied, resulting in clinical and biological improvement.

Gastric antral vascular ectasia is a rare medical condition, insufficiently recognized and poorly understood, which can be treated efficiently by endoscopic means, if it is early diagnosed. Although this condition tends to be underdiagnosed at the present time, doctors may exceed their limits by acquiring a high grade of clinical suspicion.
Black silicon – correlation between microstructure and Raman scattering
Authors: Jurečka Stanislav , Pinčík Emil , Imamura Kentaro , Matsumoto Taketoshi , Kobayashi Hikaru
Published: October 2019

Black silicon layers were formed on silicon substrate by the surface structure chemical transfer method and by anodic etching method. Properties of microstructure of formed layers were experimentally studied by the electron microscopy methods (TEM) and characterized by statistical, Fourier and multifractal methods. Theoretical structures with defined fractal properties and surface roughness were generated and their microstructure properties were evaluated. Obtained results were used for the explanation of the real structure development during the forming procedure. By using of this approach, we study the correlation of roughness and fractality with optical properties. Black silicon layers were also investigated by using of Raman scattering method. Optimized theoretical model describing the 1st order of black Si Raman scattering profile was constructed and used for evaluation of the biaxial tensile stress introduced during etching procedure.
The influence of substrate bias voltage on the electrochemical properties of ZrN thin films deposited by radio-frequency magnetron sputtering: Biomedical application
Authors: Azibi Mourad , Saoula Nadia , Aknouche Hamid
Published: October 2019

In order to study the influence of the substrate bias on the properties of ZrN thin films deposited by radio-frequency magnetron sputtering for biomedical application. Films of ZrN were grown onto 316L stainless steel substrate using radio-frequency (rf) magnetron sputtering from a pure zirconium target in Ar - N2 gas mixture. The substrate bias voltage was varied from 0 to −100 V, which produces a variation in the structural and electrochemical properties of the obtained films. The deposited films were characterized by X-Rays Diffraction, Atomic Force Microscopy, scanning force microscopy and potentiodynamic polarization.
Hillsides as Part of the Socio-Cultural Capital and Development Potential of Villages/Regions (Example of Hrušov and Oravská Lesná)
Authors: Darulová Jolana
Published: October 2019

This study is based on an analysis of local economic, environmental, social and cultural activities in the municipalities which were awarded the “Village of the Year” title, with a special focus on the Hrušov hillsides and the settlements in Oravská Lesná.

The basic historical and ethnological features of these villages include dispersion of the population, since the development period until the establishment of collective farms was characterised mainly by self-employed farmers. In both cases, it happened with a delay – in the 1970s and the 1980s. Ever since, the hillsides and settlements have become depopulated, mainly as a result of the growing construction of family houses or municipal (cooperative) flats in the central parts of municipalities.

Inspired by the theoretical and methodological framework of the authors who have dealt with the transformation of hillsides/settlements (Priečko, 2003, 2015; Huba, 1989, 1990, 2009), four possible development processes influencing the hillsides/settlements over the past decades can be hypothetically assumed:

1. Strengthening the original residential and economic function through a set of incentives.

2. Complete functional transformation of the sites from residential to recreational areas.

3. Exclusion of the sites from the category of built-up areas and delimitation of agricultural land to forest land category;

4. Combination of two and more functions with a view to a rational use of the landscape potential and preservation of the genius loci, which, however, requires the ability and willingness of the original or new users to respect the natural and cultural values of places of habitation and of the country, traditional agro-technical processes as well as landscaping in connection with the local/regional cultural heritage.
Validation of the Slovenian version of the low anterior resection syndrome score for rectal cancer patients after surgery
Authors: Grosek Jan , Košir Jurij Aleš , Novak Jerica , Omejc Mirko , Tomažič Aleš , Norčič Gregor
Published: October 2019

Purpose

The purpose of this study was to translate the low anterior resection syndrome (LARS) score into Slovenian and to test its validity on Slovenian patients who underwent low anterior rectal resection.

Methods

The LARS score was translated from English into Slovenian and then back-translated following international recommendations. The Slovenian version of the LARS questionnaire was completed by patients who underwent low anterior rectal resection between 1 January 2006 and 31 December 2010 at the University Medical Centre Ljubljana. An anchor question assessing the impact of bowel function on lifestyle was included. To assess test-retest reliability, some of the patients answered the LARS score questionnaire twice.

Results

A total of 100 patients (66.7%) of the 150 patients who were contacted for participation, were included in the final analysis. A total of 58 patients reported major LARS score. The LARS score was able to discriminate between patients who received radiotherapy and those who did not (p<0.001), and between total and partial mesorectal excision (p<0.001). Age was not associated with a greater LARS score (p=0.975). There was a perfect fit between the QoL category question and the LARS score in 66.0% of cases and a moderate fit was found in 24.0% of the cases, showing good convergent validity. Test-retest reliability of 51 patients showed a high intraclass correlation coefficient of 0.86.

Conclusions

The Slovenian translation of the LARS score is a valid tool for measuring LARS.
PEMBUATAN BAGAN WISATA UNTUK MENINGKATKAN PEREKONOMIAN NELAYAN DAN MELESTARIKAN POPULASI IKAN DI TELUK PELABUHAN RATU SUKABUMI 2017
Authors: _ Jondri , Saepudin Deni , Gunawan Putu Harry
Published: October 2019

Bagan merupakan salah satu alat tangkap ikan yang digunakan oleh nelayan, termasuk para nelayan di Teluk Pelabuhan Ratu Sukabumi. Prinsip yang digunakan adalah memancing ikan untuk berkumpul dengan bantuan cahaya lampu pada malam hari dibawah bagan dan kemudian ditangkap dengan menggunakan jaring. Sekilas cara menangkap ikan seperti ini kelihatan menguntungkan, karena jumlah ikan yang bisa ditangkap bisa cukup banyak dan tidak perlu mengeluarkan bahan bakar untuk perahu. Tapi jika dilihat dalam perspektif jangka panjang, cara menangkap ikan seperti ini tidak ramah lingkungan. Karena ikan-ikan ukuran kecil juga ikut tertangkap dan dijual dengan harga yang murah. Selain harganya murah, stock ikan dilaut juga akan semakin berkurang. Dalam jangka panjang menangkap ikan dengan cara ini dapat merugikan nelayan. Dengan semakin bertambahnya jumlah bagan yang ada di Teluk Pelabuhan Ratu dikhawatirkan akan berdampak buruk terhadap lingkungan, karena pada daerah lain sudah terjadi jumlah ikan yang bisa ditangkap setiap tahunnya menurun dengan bertambah banyaknya jumlah bagan. Untuk itu perlu diberikan alternatif pemanfaatan bagan, dengan tidak mengurangi nilai ekonomi yang bisa diperoleh nelayan. Kegiatan pengabdian masyarakat yang dilakukan berupa pembuatan bagan wisata terpadu. Bagan wisata ini tidak dibuat dari awal, tapi dikonversi dari bagan konvensional milik nelayan. Pada bagan wisata ini akan dilengkapi dengan rumpon (tempat ikan berkembang biak dan berlingdung), karamba, tempat memancing, dan restoran yang diharapkan dapat menjadi alternatif wahana wisata bagi wisatawan yang berkunjung ke Pelabuhan Ratu.
THE STUDY OF MARKET TIMING IMPLEMENTATION IN INDONESIAN STOCK MARKET
Authors: Fajri Salman , Irawan Tony , Andati Trias
Published: October 2019

This study is intended to discuss about implementation of market timing as an investment alternative strategic in Indonesian Stock Market. Market timing is procedure for changing portfolio asset allocation to deal with changes in business cycle. The market timing indicator used in this study is interest rate of Bank Indonesia. The active portfolio consist of IHSG and bond for simple rotation strategy. Sector rotation strategy consist of cyclical and non cyclical sector index. The dissecting cycle analyse by two methods, Hamilton Filter and indicator change assumptions. The secondary data used in this study have a span of time from January 2005 - December 2017. The result showed that active strategies produced better performance than passive strategy, and sector rotation were the best performance among other alternative strategies. Optimal performance of simple rotation occurs when change of variable BI rate by ±2% and optimal performance of sector rotation occurs when change of variable BI rate by ±4%.

Keywords—Hamilton Filter; Market Timing; Sector Rotation; Simple Rotation

AbstrakPenelitian ini bertujuan untuk membahas tentang penerapan market timing sebagai tindakan strategi investasi aktif di pasar modal Indonesia. Market timing merupakan prosedur perubahan alokasi aset portfolio untuk menghadapi perubahan siklus bisnis di suatu negara. Indikator market timing yang digunakan dalam penelitian ini adalah suku bunga acuan Bank Indonesia. Portfolio aktif terdiri dari IHSG dan obligasi untuk strategi aktif rotasi sederhana dan indeks sektor siklikal dan non siklikal untuk rotasi sektoral. Pemilahan siklus dilakukan dengan dua metode yaitu Hamilton Filter dan asumsi perubahan variabel indikator. Seluruh data sekunder yang digunakan dalam penelitian ini memiliki rentang waktu dari Januari 2005 - Desember 2017. Hasil penelitian menunjukkan bahwa strategi aktif menghasilkan kinerja lebih baik relatif terhadap strategi pasif, dan strategi rotasi sektoral secara keseluruhan lebih baik dibandingkan dengan alternatif strategi lain. Strategi rotasi sederhana optimal pada penggunaan asumsi perubahan variabel ±25 bps (basis point) dan strategi rotasi sektoral optimal pada penggunaan asumsi perubahan variabel ±100 bps (basis point).

Kata kunci— Hamilton Filter, Market Timing, Rotasi Sederhana, Rotasi Sektoral
EVALUASI KINERJA DIRECT CURRENT-BIASED OPTICAL ORTHOGONAL FREQUENCY DIVISION MULTIPLEXING (DCO-OFDM) TERHADAP SKALABILITAS SISTEM VISIBLE LIGHT COMMUNICATION
Authors: Pamukti Brian , Sigit Widhi Prabowo Vinsensius
Published: October 2019

Direct Current-biased Optical Orthogonal Frequency Division Multiplexing (DCO-OFDM) dengan penambahantegangan 3 V dilakukan menutupi loss 3 dB pada Asymmetrical Clipping Optical-OFDM (ACO-OFDM). Pengujianterhadap dampak dari perubahan posisi penerima terhadap kinerja dianalisis dengan mengubah sudut antarapengirim dan penerima. DCO-OFDM berbeda dengan sistem OFDM pada komunikasi seluler yang menggunakanfrekuensi radio dan nilai sinyal bipolar. Hasil simulasi komputer menunjukan bahwa jarak paling jauh daripengirim ke penerima yang dihasilkan dari sudut 24 adalah 2,413 m atau sama dengan area seluas 1,05 m2.
Let’s Uncomplicate: Mg Complexes in Mg3Sb2
Authors: Gorai Prashun , Stevanovic Vladan
Published: October 2019

A comment on "Understanding the Intrinsic p-type Behavior and Phase Stability of Thermoelectric a-Mg3Sb2" (Chong et al., ACS Applied Energy Materials, 1, 6600, 2018).
Ag- and Cu-Promoted Mesoporous Ta-SiO2 Catalysts Prepared by Non-Hydrolytic Sol-Gel for the Conversion of Ethanol to Butadiene
Authors: Dochain Denis , Styskalik Ales , Debecker Damien
Published: October 2019

The direct catalytic conversion of bioethanol to butadiene, also known as the Lebedev process, is one of the most promising solution to replace the petro-based production of this important bulk chemical. Considering the intricate reaction mechanism – where a combination of acid-catalyzed dehydration reactions and metal-catalyzed dehydrogenation have to take place simultaneously – tailor-made bifunctional catalysts are required. We propose to use non-hydrolytic sol-gel (NHSG) chemistry to prepare mesoporous Ta-SiO2 materials which are further promoted by Ag via impregnation. An acetamide elimination route is presented, starting from silicon teraacetate and pentakis(dimethylamido)tantalum(V), in the presence of a pluronic surfactant. The catalysts display advantageous texture, with specific surface area in the 600-1000 m².g-1 range, large pore volume (0.6-.1.0 cm³.g-1), an average pore diameter of 4 nm and only a small contribution from micropores. Using an array of characterization techniques, we show that NHSG allows achieved a high degree of dispersion of tantalum, mainly incorporation as single sites in the silica matrix. The presence of these monomeric TaOx active sites is responsible for the much higher dehydration ability, as compared to the corresponding catalyst prepared by impregnation of Ta onto a pristine silica support. We attempt to optimize the butadiene yield by changing the relative proportion of Ta and Ag and by tuning the space velocity. We also demonstrate that Ag or Cu can be introduced directly in one step, during the NHSG process. Copper doping is shown to be much more efficient than silver to guide the reaction towards the production of butadiene.
Asymptotic Behavior of the Exchange-Correlation Energy Density and the Kohn-Sham Potential in Density Functional Theory: Exact Results and Strategy for Approximations
Authors: Kraisler Eli
Published: October 2019

The present work is a review of two analytical properties of the exact exchange-correlation (xc) functional in density-functional theory. These properties are the asymptotic behavior of the xc energy density per particle and the asymptotic behavior of the Kohn-Sham potential, in finite many-electron systems. The derivation of the asymptotic forms for both quantities is reviewed, employing the concepts of the adiabatic connection and of the xc hole with relation to the first quantity and the electron exact factorization approach for the second one. Furthermore, it is shown that the correct asymptotic behavior of one of the aforementioned quantities does not guarantee a correct behavior of the other. In this process, a new quantity, the xc hole response function, is defined and its exact exchange part is analytically derived. The extent to which existing xc approximations satisfy the named exact properties is reviewed and the relationship between correct asymptotics and freedom from one-electron self-interaction in DFT is discussed. Finally, a strategy for development of advanced approximations for exchange and correlation with a correct asymptotic behavior is suggested.
Triple Self-Sorting in Constitutional Dynamic Networks: Parallel Generation of Cu(I), Fe(II) and Zn(II) Imine-Based Metal Complexes
Authors: Ayme Jean-François , Dhers Sébastien , Lehn Jean-Marie
Published: October 2019

Three imine-based metal complexes, having no overlap in terms of their compositions, have been simultaneously generated from the self-sorting of a constitutional dynamic library (CDL) containing three amines, three aldehydes and three metal salts. The hierarchical ordering of the stability of three metal complexes assembled and the leveraging of the antagonistic and agonistic relationships existing between the constituents within the constitutional dynamic network corresponding to the CDL were pivotal in achieving the desired sorting. The mechanism and the driving forces underlying the self-sorting process have been studied by NMR. The self-sorting of the Fe(II) and Zn(II) complexes was found to depend on an interplay between the thermodynamic driving forces and a kinetic trap involved in their assembling. These results also exemplify the concept of “simplexity” –the fact that the output of a self-assembling system may be simplified by increasing its initial compositional complexity—as the two complexes could self-sort only in the presence of the third pair of organic components, those of the Cu(I) complex.
Chromatin remodeler Fft3 plays a dual role at blocked DNA replication forks
Authors: Ait-Saada Anissia , Khorosjutina Olga , Chen Jiang , Kramarz Karol , Maksimov Vladimir , Svensson J Peter , Lambert Sarah , Ekwall Karl
Published: October 2019

Here, we investigate the function of fission yeast Fun30/Smarcad1 family of SNF2 ATPase-dependent chromatin remodeling enzymes in DNA damage repair. There are three Fun30 homologues in fission yeast, Fft1, Fft2, and Fft3. We find that only Fft3 has a function in DNA repair and it is needed for single-strand annealing of an induced double-strand break. Furthermore, we use an inducible replication fork barrier system to show that Fft3 has two distinct roles at blocked DNA replication forks. First, Fft3 is needed for the resection of nascent strands, and second, it is required to restart the blocked forks. The latter function is independent of its ATPase activity.
As ações do violonista em Sonant, de Mauricio Kagel
Authors: Oliveira Weiss Ledice Fernandes de
Published: October 2019

Este artigo analisa o papel do performer-instrumentista no teatro instrumental criado pelo compositor Mauricio Kagel, tomando como objeto a atuação do violonista em uma de suas primeiras peças no gênero, Sonant (1960). Escrita para quatro instrumentistas, esta obra se baseia na teatralização da própria situação de concerto a partir de uma partitura que combina um material sonoro propriamente dito (notado parcialmente de forma tradicional, e parcialmente segundo formas inovadoras para a época, como a notação gráfica e a descrição verbal de ações) com a proposição de situações cênicas diversas. Estas não partem da ideia de representação teatral, mas de uma teatralidade situacionista. Assim, as diversas ações que são propostas ao violonista lhe demandam não apenas uma técnica instrumental aprimorada e expandida, com o uso de diversos recursos recentemente explorados no instrumento, como a integração de outras fontes sonoras, ações cênicas e reações coletivas aos estímulos dados. A forma musico-teatral resultante introduz não apenas a inovação de tradições enraizadas, como também a possibilidade de uma estética que transita entre o previsto e o imprevisto, trazendo à frente a contribuição artística dos intérpretes na própria construção formal da obra, centralizando a musicalidade no gesto e propondo, enfim, uma reflexão sobre a própria prática artística.
Tributes to Prof David Sanders
Authors: Witten Chantell , Greiner Ted , Recine Elisabetta , Keith Regina
Published: October 2019

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Exploring Infant and Young Child Feeding Practices in the Royal Borough of Greenwich, London, to Improve Health and Nutrition Outcomes in Children Under 2 Years of Age
Authors: Kenyangi Beijuka Diana , Keith Regina Susan , Adegboye Amanda R. Amorim
Published: October 2019

Introduction: The UK, like many other countries, is struggling to achieve two of the Global Nutrition Targets, namely increasing exclusive breastfeeding and halting the rise of childhood obesity. Identifying the infant feeding interventions that are having an impact could increase the effectiveness of cash strapped public health services in London. Improving infant feeding practices could also help halt the dangerous rise in childhood obesity.

Study Aim: This study explored the Infant and Young Child Feeding (IYCF) practices and support in place to improve health and nutrition outcomes of children under 2 years of age in the Royal Borough of Greenwich, London

Methodology: The study applied a qualitative methodology, supplemented with data on demographic characteristics of participants, collected via standardised questionnaires prior to the qualitative data collection. Categorical data are presented as absolute (n) and relative frequency (%). Qualitative data were collected using focus group discussions, semi structured interviews and key informant interviews and analysed using a thematic approach.

Participants: The total sample included 35 participants: four focus groups with fifteen mothers, nine semi structured interviews, six with mothers and three fathers--all with at least one child in the target age group--and 11 key informants.

Findings: Five main themes and twenty-five subthemes emerged from the qualitative data including a high level of awareness on the importance of infant feeding practices. However, only six of the key informants were aware of the borough IYCF Policy. Key informants felt that they personally would benefit from more training and resources, while more support from health workers, family and friends was very important for the other participants. Support services offered at the Children’s Centres appeared to be the most effective, in comparison to support at hospital and at home. There was a lack of cohesion among messages given at the different points of care of breastfeeding moms. Respondents reported that the Borough was implementing some aspects of its infant feeding support programmes effectively, especially through the breastfeeding support groups.

Conclusions: Continuous monitoring and evaluation of current programmes and creation of sustainable links between all points of care from antenatal to postnatal period will help the Borough in achieving improved breastfeeding rates. This should improve health and nutrition outcomes for children under 2 years of age in the borough.
Absceso de Psoas Secundario a un Adenocarcinoma Mucinoso de Colon Perforado: Semiología.
Authors: Ortiz Sierra Lina María , Ferreira Gonzalo Bernal , Duarte Andrés Mauricio
Published: October 2019

El absceso de psoas secundario a adenocarcinoma mucinoso de colon perforado, es una entidad poco frecuente que ocurre en el 1,8 % de la población, lo que dificulta su diagnóstico e incrementa su morbimortalidad (1).

A nuestra institución ingresa un paciente con diagnóstico de absceso de psoas de etiología desconocida pálido en regulares condiciones generales, antecedentes de drenajes a repetición, al examen físico presencia de catéter sobre cresta iliaca derecha con salida de escaso líquido seroso purulento, paraclínicos con evidencia de anemia normocítica heterogenia, trombocitosis y eosinofilia.

Como posible diagnostico se consideró espondilodiscitis, se realizó una radiografía de tórax para descartar tuberculosis pulmonar y RMN (Resonancia Magnética Nuclear) que reveló solución de continuidad en la pared posterior del ciego con colección que se extendía en la pared lateral de la pelvis. Afectando el componente iliaco del músculo psoas iliaco derecho, hallazgo sugestivo a lesión tumoral, probablemente adenocarcinoma mucinoso de ciego perforado.

Paciente se lleva a hemicolectomia derecha con reporte histopatológico de tumor en el ciego con perforación macroscópica presente de tipo adenocarcinoma de patrón mucinoso de alto grado con pobre respuesta linfoide, extensión hasta la serosa con perforación, metástasis a 2 ganglios e implantes tumorales al mesogastrio, clasificación pT4N1M1. Se instauro manejo con drenaje, antibioticoterapia, hierro y se inició proceso de remisión a clínica oncológica.

El caso nos permitió reconocer el rendimiento operativo de las pruebas diagnósticas y de la importancia de su integración con la semiología del paciente, elementos que fueron fundamentales para llegar a un diagnóstico certero.
Occurrence of caffeine in wastewater and sewage and applied techniques for analysis: a review
Authors: Marasco Júnior César Augusto , Luchiari Natália Da Costa , Lima Gomes Paulo Clairmont Feitosa
Published: October 2019

Emerging contaminants are substances found in the environment whose concentrations vary from µg to ng L-1 and whose presence in wastewater has gained popularity in the scientific community due to the potential impacts these compounds can cause to the environment. This designation concerns the lack of legislation to regulate their discharge or even to monitor these compounds. Moreover, emerging contaminants are capable of causing harmful effects to nontarget organisms and therefore affect the ecosystem balance. There are several compounds classified as emerging contaminants such as pharmaceuticals, illicit drugs, hormones, pesticides, among others. And among them, caffeine is considered an emerging contaminant and can be highlighted due its presence in medicines, beverages, foodstuff and several other products. In addition, it is a compound used worldwide recognized as a marker of anthropogenic activity. In this review, we present a discussion about emerging contaminants, focusing on caffeine, regulatory aspects that involve the theme, as well as effects on organisms, removal technologies and techniques for analyzing these compounds in environmental matrices.
ELECTRONIC EDUCATIONAL
RESOURCES OF TEACHING OF THE
BASIS OF DESKTOP PUBLISHING FOR
THE FUTURE TEACHERS OF
VOCATIONAL EDUCATION
Authors: Medvediev Roman , Shevchenko, Liudmyla , Umanets Volodymyr
Published: October 2019

The article describes the experience of designing and using in the process
of training future educators professional training of electronic educational
resource for the study of computer layout foundations. In the course of
our research, we have found out the possibility of using electronic
educational resources in the educational process of Higher education
institutions to train future teachers of vocational education. In particular,
we have developed an electronic educational resource «Basics of
Computer Layout», in which, according to, the necessary training
materials and author's methodological developments for learning the
basics of computer layout in the Adobe InDesign CS5 software
environment are structured. The Word Press content management
system (CMS), which has open source code and is distributed under the
GNU GPL license, has become a popular medium for creating the
described ESM. The developed ESM contains a set of copyright
educational and methodological materials, materials for monitoring the
level of educational achievements, together they allow the future
teachers of vocational training to form the theoretical knowledge and
practical skills of the basics of computer layout in the Adobe InDesign
CS5 software environment. For the purposeful implementation of
conceptual research ideas, the author developed a method for using a
complex of electronic educational resources for teaching computer
graphics to future bachelors of the specialty 015.10 «Professional
education (computer technologies)». The method involves the provision
of practical knowledge and skills to future bachelors of vocational
education in order to form professional competencies in the Special Informatics discipline (module 3 Fundamentals of computer layout in the
Adobe In Design CS5 program).
USING OF DIGITAL TECHNOLOGIES FOR
FORMATIVE ASSESSMENT
Authors: Morze Nataliia , Vember Viktoriia , Boiko Mariia
Published: October 2019

The article deals with the problem of using modern digital technologies
for formative assessment. The main objectives of the assessment, such
as "assessment for learning", "assessment as learning" and "assessment
of learning", are analyzed, and it is stated that the first two objectives
are realized precisely by means of formative assessment. The evaluation
strategies that the teacher can use to collect data on student
achievements is analyzed. The objectives of formative assessment before
the beginning, during the process of work and at the end of the lesson
are determined; as well as methods of formative assessment. The
structure of the formative assessment process consisting of six steps is
analyzed. In today's conditions, for the implementation of formative
assessment, it is expedient to involve digital technologies. Therefore, the
article proposes a classification of digital resources that can be used for
formative assessment at different stages of the occupation and for
different purposes, examples are given and a description of possible use
of resources of each specified category. In particular, such digital
resources as quizzes, surveys, online tests, virtual boards, multiservices
for creating interactive tasks with the possibility of self-checking their
correctness, word-of-mouth word services, mindmaps, services for
creating infographics and visualization, keeping diaries are considered.
Different ways of using virtual boards for formative assessment are
offered, and examples are given of their application before the beginning
of the class, in the process of work and at the end of the lesson for
reflection. The research leading to these results received, within the
framework of the Modernization of Pedagogical Higher Education by
Innovative Teaching Instruments. MoPED – KA2 CBHE – 586098-EPP-1-
2017-1-UA-EPPKA2-CBHE-JP.
USE OF DIGITAL TECHNOLOGIES IN THE EDUCATIONAL ENVIRONMENT OF HIGHER EDUCATION
Authors: Antonova Elena , Familyarskaya Larissa
Published: October 2019

The article systematized regulatory documents that characterize the need for transformation processes in education, which include updating the knowledge system and the need for adapting the teacher of higher education institutions to changes in interpersonal interaction with the use of digital technologies. The notions of "digital environment", "digital technologies", "digitalization" are disclosed. It was clarified that there was no single approach to the definition of "digital technologies" in scientific circles and national legislative documents. The peculiarities of the digital technologies implementation created by the local network of higher educational institutions through the module of administration and adjustment of the users rights, which ensures the implementation of participants activities in the educational process without territorial, geographical, time constraints, are described. The essential characteristics of educational tasks and digital technologies used for their representation are described that allows a teacher to create conditions for active student learning activities in the educational electronic environment. Possibilities of updating forms of interpersonal interaction in the context of educational tasks are generalized. The digital technologies providing feedback are characterized, in particular, through the final and formative assessment. There are three criteria for selection of digital means and technologies: provision of interactive information interaction in the learning process; adaptation to the individual characteristics of students; possibility of synchronous or asynchronous interaction of an educational activity participants. The effectiveness of using digital technologies in the educational process of the higher institution education has been revealed according to the survey of students and teachers. It is revealed that the efficiency of digital technologies' use depends and is determined by a higher educational institution teacher’s readiness for this process .
INNOVATIVE METHODS OF EDUCATION
AS A BASIS FOR HIGH-QUALITY
VOCATIONAL TRAINING OF PHYSICAL
EDUCATION TEACHERS
Authors: Otravenko Olena
Published: October 2019

The article is focused on the implementation of innovative teaching
methods for the quality improvement of vocational training of future
physical education specialists, creation of conditions for productive
creative professional activities and harmonious development of the
individual and provision of opportunities for the creative use of the
newest teaching methods in the information and educational space of
higher educational institutions. The quality of training of future physical
education teachers in higher educational institutions is a system-integral
unity of its procedural and productive characteristics, which is
characterized by professional and personal development of future
specialists who are competitive and able to understand the valuesemantic
context of educational activity, increase creative potential, find
non-standard solutions for vocational and educational tasks as well as
capable of vocational self-determination and self-realization. The article
deals with the description of teaching methods: contextual, gaming,
problem-based, modular, full knowledge acquisition and distance
learning. Teachers have been using more frequently active and
interactive methods like case-methods, brainstorming, and training as
the forms of educational work. Students regularly perform practical and
creative tasks; a large number of seminars are held in the form of
discussions, business games and master classes. The expansion of
innovative processes in the educational space of the institution of higher
education has become a significant driving factor for the formation of
new mechanisms for vocational training and the creation of an internal
system of education quality that contains the development if innovative
methods, processes and resources presented in organizational and
regulatory documents, various procedures for controlling the quality of vocational training of applicants and the main activities of the institution
of higher education.
PECULIARITIES OF INNOVATIVE
TEACHING INSTRUMENTS APPLICATION
DURING PROFESSIONAL TRAINING OF
FUTURE TEACHERS OF MATHEMATICS
Authors: Sinyukova Helena , Chepok Oleg
Published: October 2019

Peculiarities of innovative teaching instruments application during the
professional training of future mathematics teachers of secondary
education institutions are considered in the article. The authors assume
that an education of a student of a higher educational institution is
significantly different from their education at an educational institution of
a lower level by the fact that during a very short period of time it is
necessary to master effectively a very large amount of information, gain
a lot of corresponding skills. The fact is determinant for choosing
appropriate innovative teaching instruments and specific forms of their
implementation in institutions of higher education in general and in
institutions of higher pedagogical education in particular. Vocational
subjects for future teachers of mathematics can be divided into three
groups: pedagogy and psychology, courses of mathematics in institutions
of secondary education and methods of their teaching, mathematical
disciplines of higher mathematical education. Only the training courses of
the last two groups are considered. The general characteristic of their
current state is given. The comparative analysis of the modern
methodological concept of training courses packages formation in higher
mathematics for future mathematics teachers of institutions of secondary
education and the corresponding methodological concept of the 70-80s of
the last century was represented. The necessity of thorough systematic
work of every teacher of higher mathematics on the formation of the
students' perception of the necessity of a precise substantiation of all
statements to be proved is highlighted, that is, on the perception of the
necessity of full argumentation in all cases, on the formation of
appropriate skills. Fundamentally important directions for such a work
are outlined. Problem-oriented training is defined to be the most appropriate innovative technology for the third-level educational
disciplines, based on own experience, examples of such training methods
for different types of training sessions and control measures are
provided. The authors’ understanding of practice-oriented training is
formulated. Changing of fundamental nature in curriculum of future
teachers of mathematics are proposed after careful argumentation.
According to the authors’ point of view such changes can ensure the
sufficient level of practice-oriented training. Directions of further research
are outlined.
THE MAIN COMPONENTS OF THE
METHODICAL SYSTEM OF USING THE
CLOUD-BASED LEARNING
ENVIRONMENT FOR THE PREPARATION
OF FUTURE IT SPECIALISTS
Authors: Vakaliuk Tetiana , Medvedieva Mariia
Published: October 2019

The article analyzes the readiness of HEI teachers to use a cloud-based
learning environment in the training of future IT professionals, which
showed that 59% of the interviewed teachers have an understanding of
cloud technologies and services; 34% use cloud-oriented learning tools
when teaching their subject; 16% of teachers use a cloud-oriented
learning environment in their professional and pedagogical activities;
100% of respondents agreed to use a cloud-based learning environment
designed by the author's methodological system in the educational
process. It is investigated whether the designed cloud-based training
environment for the training of future IT specialists is effective by the
criteria and indicators. The main components of the methodological
system of using cloud-based learning environment (CBLE) training of
future information technology specialists (purpose and content, methods,
forms and means of using CBLE in the educational process of higher
education institution) are described. It is established that when
constructing a methodological system for the use of cloud-oriented
training environment for training future IT professionals, it is necessary
to: select a cloud-oriented system of training support as a component of
CBLE for use in the educational process of future information technology
specialists, as well as cloud-oriented, IT-trained expedient for future IT
professionals to use in their training; improve the content of disciplines
directly related to programming for the use of a cloud-based learning
support system and cloud-based learning tools when studying different
subject disciplines in this area; to develop the "Cloud Technologies in
Education" elective course, and to implement it to acquaint with the peculiarities of the use of cloud technologies in the educational process of
future IT professionals, as well as to train teachers with the purpose to
acquaint with the peculiarities of the use of cloud technologies in the
educational process.
WAYS OF FORMING INFORMATION AND
DIGITAL COMPETENCE OF
EDUCATIONAL PROCESS PARTICIPANTS
Authors: Dudka Olga
Published: October 2019

In the article the meaning a competence approach to learning in modern
education and relation of key and object competencies are analyzed. The
attention is concentrated on the importance of forming information and
digital competence for all educational process participants, which
contributes to improving the level of performance of their professional
and social activities. It is established that an effective and dynamic
informational and educational environment is necessary for the
implementation of different forms of study in a modern educational
institution. Based on this, a problem of providing educational and
scientific space with the necessary resources is actual and important. The
possibilities of organizing informational and educational environment of
an educational institution based on cloud-oriented technologies are
considered. The examples of their application in different directions of
educational institution activity are given. One way of solving problem of
forming the informational and educational space is proposed, that is
developing digital education resources and their implementation in
educational process. The experience of the Faculty of Mathematics and
Computer Science of Vasyl Stefanyk Precarpathian National University is
described in the example of implementation of G Suite for Education that
is a suite of tools designed to empower educators and students. G Suite
for Education provides wide opportunities for innovation in organizing the
educational process, in general, and in creating digital educational
resources, in particular. It is noted that the involvement in the process of
development and testing of digital educational resources during the study
gives students an opportunity to feel themselves as active players of
educational activity and to be responsible for the result of this activity.
The digital educational resources developed by teachers and students
during the study (implementation of project, credit, exam, course and master's papers), as well as during scientific and pedagogical researches,
which have been approbated and implemented in the educational
process, are considered. The prospects of further experimental work are
determined.
DESCRIPTION OF EDUCATOR’S DIGITAL
COMPETENCE
Authors: Morze Nataliia , Bazeliuk Oleksandr , Vorotnikova Iryna , Dementiievska Nina , Zakhar Olha , Nanaieva Tetiana , Pasichnyk Oksana , Chernikova Liudmyla
Published: October 2019

Description of educator’s digital competence contains standards of
structure and digital competence levels required for successful
professional engagement of educators under the conditions of digital
society development as well as dictionary of used terms.
Description of educator’s digital competence is developed according to
Concept of pedagogical education development, European framework
documents on digital competence - DigComp 2.1: The Digital
Competence Framework for Citizens with eight proficiency levels and
examples of use, Digital Competence Framework for Educators
(DigCompEdu); Report made by participants of the
project Erasmus+ Modernization of Pedagogical Higher Education by
Innovative Teaching Instruments (MoPED).