bluuebunny/crossref_metadata_2025 huggingface dataset:
Non-Invasive Three-Dimensional Breast Tumor Positioning Before Neoadjuvant Systemic Therapy as Promissing Alternative to the Invasive Tumor Marking – Technique Description and Feasibility
Authors: Bjelica Dragana , Colakovic Natasa , Opric Svetlana , Zdravkovic Darko , Loboda Barbara , Petricevic Simona , Gojgic Milan , Zecic Ognjen , Skuric Zlatko , Zecic Katarina , Ivanovic Nebojša
Published: March 2024

Background: Surgical excision of the lodge of the tumor that has completely clinically regressed after neoadjuvant systemic therapy (NAST) is a necessary part of the treatment of early breast cancer. However, it is significantly hampered by the lack of a spatial landmark concerning the location of the pre-existing tumor in the breast. Standard surgical techniques of targeted excision of the pre-existing tumor bed generally rely on invasive insertion of various markers into or around the tumor before starting NAST. Invasive marking techniques are burdened by the disadvantages of technical complexity, invasiveness of procedures, and insufficient precision.
Methods: In this paper authors present an original technique of non-invasive determining of the tumor position in the breast in three dimensions before starting NAST, with intention to overcome the disadvantages of invasive tumor marking. Tumor positioning is performed by ultrasound measurements – detailed description of the technique is given in the main text. The feasibility and precision of the technique was tested by the histological parameters of the adequacy and rationality of excision of the tumor bed, after complete clinical regression of the tumor after NAST, on a pilot series of patients.
Results: A pilot series of 33 patients underwent a non-invasive breast tumor positioning technique before starting NAST. Twelve patients with complete clinical regression after NAST have been operated using a non-invasive tumor positioning technique, so far. In all cases, histological signs of tumor regression were verified in the specimen of the excised tumor bed. The ratio of the resected specimen volume to the volume of the tumor before NAST was on average 0,91, which is in favor of the rationality of excision and a good aesthetic effect.
Conclusion: The initial results of a pilot series of treated patients imply that a non-invasive three-dimensional tumor positioning technique is feasible, with a satisfactory level of oncological safety and aesthetic effects of surgery. Performing a randomised clinical trial comparing this technique with standard techniques of invasive tumor marking is justified.
Potential of TiO2 as a Capping Layer for Industrial c-Si PERC Solar Cells
Authors: Siddiqui Aamenah , Usman Muhammad , Hallén Anders
Published: March 2024

Titanium dioxide (TiO2) has gained popularity specially in photovoltaic applications, owing to its transparency in the visible region, and scratch resistance. In this work, the potential of TiO2 as a capping layer for c-Si p-type SiNx passivated emitter and rear contact (PERC) solar cells is studied through extensive optical and device simulations. The bifacial PERC solar cell model used in this study is calibrated with an experimental device having an efficiency of 22.19%. Device simulation results show that TiO2 deposited by the mesoporous technique outperforms atmospheric pressure chemical vapor deposition (APCVD) and atomic layer deposition (ALD) based TiO2 layers when capped over SiNx (n = 2.1) passivated solar cells. Furthermore, it is shown that the efficiency of SiNx(n = 2.1)/TiO2 based solar cells is maintained, even when the TiO2 layer thickness varies from 75 to 95 nm. To enhance the efficiency further, the type of SiNx layer (characterized by the n value), and the thicknesses of SiNx and TiO2 layers are optimized simultaneously to find the best combination of these parameters. The best front side solar cell efficiency of 22.43%, is obtained when a stack of SiNx(n = 1.99)/TiO2 (t = 58/76 nm) is used. Similarly, a rear side efficiency of 16.59% is achieved when the rear side Al2O3/SiNx stack is capped with mesoporous TiO2. These efficiencies are 0.24 and 1.25% higher, respectively, when compared to the original SiNx passivated PERC solar cell, demonstrating the prospective of using TiO2 in commercial photovoltaic applications.
Enhanced Security Hash Function Leveraging Chaotic Coupling Coefficient in Cross-Coupled Map Lattice
Authors: Li Yuxuan
Published: March 2024

The recent surge in interest within the scientific community towards spatiotemporal chaos underscores its potential for bolstering secure communications and cryptographic mechanisms. This research presents a cutting-edge methodology to amplify the spatiotemporal chaos exhibited by conventional cross-coupled image lattices through the adoption of chaotic coupling coefficients. By innovatively adjusting the structure of these lattices to incorporate chaotic coupling coefficients, we markedly enhance their chaotic dynamics across temporal and spatial dimensions. This advancement facilitates the creation of a secure hash function characterized by substantial security enhancements. Rigorous experimental validation attests to the security, highlighting the chaotic coupling coefficients' pivotal role in augmenting the hash function's defenses against various attacks. This investigation not only introduces a revolutionary alteration to the framework of cross-coupled image lattices but also unveils a pragmatic secure hash function application, demonstrating the significant potential of chaotic systems in the sphere of cryptography. Our findings suggest that integrating chaotic coupling coefficients into cross-coupled image lattices represents a fertile ground for crafting sophisticated cryptographic instruments, thereby paving new pathways in the realm of secure digital communications.
Biosynthetic potential analysis of an Arctic marine-derived strain Aspergillus sydowii MNP-2
Authors: Fu Zhiyang , Gong Xiangzhou , Hu Zhe , Wei Bin , Zhang Huawei
Published: March 2024

Genome mining strategy plays a key role in the discovery of bioactive secondary metabolites (SMs) from microorganisms. This work highlighted deciphering the biosynthetic potential of an Arctic marine-derived strain Aspergillus sydowii MNP-2 by a combination of whole genome analysis and antiSMASH as well as feature-based molecular networking (MN) in the Global Natural Products Social Molecular Networking (GNPS). A completed genomic assembly of 34.9 Mb containing 10 contigs with an N50 scaffold size of 4.1 Mb was generated and a total of 13,218 protein-coding genes and 46 rRNA, 7 sRNA, 32 snRNA and 119 rRNA were annotated using Nr, GO, COG, Pfam, KEGG and other databases. AntiSMASH results indicated that strain MNP-2 harbors 52 biosynthetic gene clusters (BGCs), suggesting a great potential for producing SMs with various structure motifs. Noticeably, these BGC-encoded SMs with therapeutic potential were detected in its metabolic products through GNPS and MN analyses.
Causal Relationship Between Plasma Lipidome and Six Types of Cancer: A Mendelian Randomization Study
Authors: Tang Jincheng , Zhang Jingting , Yang Renyi , Chen Hongyao , Zeng Puhua
Published: March 2024

Background: The plasma lipidome is intricately associated with cancer. However, the causal relationship between them remains uncertain. Therefore, this study employs Mendelian randomization (MR) based on genetic principles to investigate the potential causal relationship between plasma lipidome and six common types of cancer.
Methods: MR analysis utilizes publicly available genetic data, employing a genome-wide association study (GWAS) of 179 lipid species as exposure and GWAS datasets of six different cancers as outcomes. The inverse variance weighted (IVW) method serves as the primary approach, with MR-Egger regression and weighted median (WM) method employed as supplementary methods for analysis. Additionally, sensitivity analyses including Cochran's Q test, MR-Egger intercept test, and leave-one-out analysis are conducted to assess the reliability and stability of causal relationships. The Steiger test is also utilized to determine the directionality of causal relationships.
Results: The IVW analysis reveals that phosphatidylethanolamine (16:0_20:4) levels and others are implicated as risk factors for hepatic cancer, while sphingomyelin (d40:1) levels and others are identified as protective factors against hepatic cancer. Sterol ester (27:1/20:4) levels and others are associated with increased risk of lung cancer, whereas sterol ester (27:1/18:2) levels and others are associated with decreased risk of lung cancer. Sterol ester (27:1/20:3) levels and others are identified as risk factors for colorectal cancer, whereas phosphatidylcholine (18:2_0:0) levels and others are protective against colorectal cancer. Phosphatidylcholine (16:0_20:4) levels and others are linked to increased risk of esophageal cancer, while phosphatidylcholine (16:0_18:3) levels and others are associated with protection against esophageal cancer. Phosphatidylinositol (18:0_20:4) levels and others are identified as risk factors for thyroid cancer, whereas phosphatidylinositol (16:0_18:2) levels and others are protective against thyroid cancer. Diacylglycerol (18:1_18:2) levels and others are identified as protective factors against breast cancer.
Conclusions: There exists a clear causal relationship between plasma lipidome and six types of cancer. Additionally, it has been observed that the same single-nucleotide polymorphisms (SNPs) serve as instrumental variables (IVs), influencing cancer through the plasma lipidome. This provides further avenues and methodologies for early screening and effective treatment of cancer.
Integrin-linked kinase-frizzled 7 interaction maintains cancer stem cells to drive platinum resistance in ovarian cancer
Authors: Atwani Rula , Rogers Amber , Nagare Rohit , Prasad Mayuri , Lazar Virginie , Sandusky George , Pin Fabrizio , Condello Salvatore
Published: March 2024

Background
Platinum-based chemotherapy regimens are a mainstay in the management of ovarian cancer (OC), but emergence of chemoresistance poses a significant clinical challenge. The persistence of ovarian cancer stem cells (OCSCs) at the end of primary treatment contributes to disease recurrence. Here, we hypothesized that the extracellular matrix protects CSCs during chemotherapy and supports their tumorigenic functions by activating integrin-linked kinase (ILK), a key enzyme in drug resistance.
Methods
TCGA datasets and OC models were investigated using an integrated proteomic and gene expression analysis and examined ILK for correlations with chemoresistance pathways and clinical outcomes. Canonical Wnt pathway components, pro-survival signaling, and stemness were examined using OC models. To investigate the role of ILK in the OCSC-phenotype, a novel pharmacological inhibitor of ILK in combination with carboplatin was utilized in vitro and in vivo OC models.
Results
In response to increased fibronectin (FN) secretion and integrin β1 clustering, aberrant ILK activation supported the OCSC phenotype, contributing to OC spheroid proliferation and reduced response to platinum treatment. Complexes formed by ILK with the Wnt receptor frizzled 7 (Fzd7) were detected in tumors and showed a strong correlation with metastatic progression. Moreover, TCGA datasets confirmed that combined expression of ILK and Fzd7 in high grade serous ovarian tumors is correlated with reduced response to chemotherapy and poor patient outcomes. Mechanistically, interaction of ILK with Fzd7 increased the response to Wnt ligands, thereby amplifying the stemness-associated Wnt/β-catenin signaling. Notably, preclinical studies showed that the novel ILK inhibitor compound 22 (cpd-22) alone disrupted ILK interaction with Fzd7 and CSC proliferation as spheroids. Furthermore, when combined with carboplatin, this disruption led to sustained AKT inhibition, apoptotic damage in OCSCs and reduced tumorigenicity in mice.
Conclusions
This “outside-in” signaling mechanism is potentially actionable, and combined targeting of ILK-Fzd7 may represent a new therapeutic strategy to eradicate OCSCs and improve patient outcomes.
Die Komplexität sozialverantwortlicher Handlungsentscheidungen
Authors: Tiede Jennifer
Published: March 2024

Rezension zu
Tulodziecki, Gerhard. 2023. Individuelles Handeln und Gemeinwohl. Eine interdisziplinäre Handlungstheorie im Kontext von Freiheit, Verantwortung und künstlicher Intelligenz. Bielefeld: transcript. https://doi.org/10.1515/9783839468173.
Komunikasi Politik di Negeri Sarawak: Analisis Wacana Kritis Terhadap Manifesto Parti Politik dalam Pilihan Raya Negeri Sarawak 2021
Authors:   Faculty of Language and Communication, Universiti Malaysia Sarawak, Sarawak, Malaysia, Taibi Malia , Ahmad Rizal Ammar Redza ,   Center for Research in Media and Communication, Faculty of Social Sciences and Humanities, Universiti Kebangsaan Malaysia, Selangor, Malaysia, Hussin Siti Haslina ,   Faculty of Language and Communication, Universiti Malaysia Sarawak, Sarawak, Malaysia
Published: March 2024

An election manifesto reflects the vision of a political party in its effort to gain support from potential voters to win seats. Most political parties will produce manifestoes that promise development projects to drive the country’s economy, provide employment opportunities as well as combat abuse of power. The 2021 Sarawak State Election (SSE21) was an election that attracted the attention of state and federal observers. For the first time, the Gabungan Parti Sarawak (GPS) was contesting after the disbandment of Sarawak Barisan Nasional (BN) in 2018. In addition, it was also the first election for the new Sarawak Chief Minister, Abang Johari Openg. SSE21 was the first battleground for several Sarawak nationalist parties such as Parti Sarawak Bersatu (PSB) and Parti Bumi Kenyalang (PBK). Using critical discourse analysis, this article aims to analyse the content of GPS, PSB and PBK’s manifestoes. The focus of this study is the issue of state nationalism, state development and inter-ethnic relations presented in the manifesto.
Social Media Discourse in Sarawak: An Analysis of Popular Issues and Their Correlation with the Gabungan Parti Sarawak Manifesto in 2021
Authors:   Faculty of Social Sciences and Humanities, Universiti Malaysia Sarawak, Sarawak, Malaysia, Mohamad Naim Hafizan , Mohd Sani Mohd Azizuddin ,   School of International Studies, Universiti Utara Malaysia, Kedah, Malaysia
Published: March 2024

Social media, notably Facebook, has been reported to be actively used by all, particularly when expressing opposing perspectives on various matters related to Sarawak and Sarawak’s interests. The debate became more interesting during the period of political change in 2018 when Sarawak began to realign its position within a shifting political landscape. Consequently, the realignment had also influenced the framing of the Gabungan Parti Sarawak (GPS) manifesto during the 2021 Sarawak State Election (SSE21). The article attempts to identify the popular issues circulated in social media and to correlate them with the highlighted issues embedded in the GPS manifesto in SSE21. Data was collected from Facebook from 20 December 2018 to 26 January 2019 through historical data retrieval process. About 197 high-engagement posts were selected as the dataset. Thematic analysis was used in the analytic methods, which was carried out using QSR NVivo 12 Plus. Six main topics were identified that served as focal points of discussion for online discourse in Sarawak: sociocultural topics; economic topics; political topics; development topics; constitutional and legal topics; and border and security topics. Among the topics, three main issues have been identified to be crucial for Sarawakians: (1) constitutional and legal issues – issues that are related to Sarawak rights, Malaysia Agreement 1963 (MA63), and federal and state constitution; (2) sociocultural issues – regional sentiments that are related to the ideals of being a Sarawakian; and (3) political issues – issues of federal-state relations. It is suggested that as the online discussion of the issues gains traction, Sarawakians are observed to be more engaged in topics within the framing of their perceived position within the federation, specifically relating to the preferred position of their identity as Sarawakian first as opposed to Malaysian first. The formation of GPS as a local-based coalition has immensely benefited GPS since it is consistent with its agenda of “Sarawak First”. The study’s findings imply that there is consistency between the topics raised by Sarawakians during Sarawak’s term as an opposition state in 2018 and the themes contained in the GPS manifesto during the SSE21.
KNOWLEDGE ATTITUDE AND AWARENESS REGARDING ZNO SUNSCREEN PROTECTION AMONG UNDERGRADUATE DENTAL STUDENTS
Authors:   Student(BDS),DepartmentofPublicHealthDentistry,MamataDental College,Khammam,India., Maria Alphonsa Deepthi T. , Pratap K.V.N.R. ,   Professor andHOD,Department ofPublicHealthDentistry,MamataDental College, Khammam, India., Madhavi Padma T. ,   Professor,Department ofPublicHealthDentistry,MamataDentalCollege, Khammam,India., Siva Kalyan V. ,   Reader,DepartmentofPublicHealthDentistry,MamataDentalCollege, Khammam,India., Srujan Kumar V. ,   SeniorLecturer,Department of PublicHealthDentistry,MamataDental College, Khammam,India.
Published: March 2024

Background:Zincoxidenanorods were employed as the primary ultra- violet protection agent in the formulation of sunscreens. Examination of ZnO powder through FESEM and TEM micrographs revealed the predominant presence of rod-like structures with a width range between 61-70 nm. Notably, sunscreens containing 20-40% (by weight) of ZnOnanorods exhibited significantly improved UV absorbance across both UVA and UVB spectra (280-400 nm). This study mainly aims to assess the Knowledge Attitude and Awareness Regarding ZnOnanorodsinSunscreenProtectionAmongUndergraduateDentalStudents. Aim: Knowledge Attitude and Awareness Regarding ZnO Sunscreen Protection Among Undergraduate Dental Students. Objective: Analyzing and determining the Knowledge Attitude and Awareness Regarding ZnO Sunscreen Protection Among Undergraduate Dental Students. Method: A cross sectional study was conducted among the dental students (II,III, IV, interns) in a tertiary care teaching hospital,Khammam, using a web basedtool called forms pro, a semi-structural online questionnaire was designed and distributed to the students in order to fill.Descriptive statistics were calculated using SPSS verson-29..A p- value <0.05 was used to evaluate statistical significance. Result: A total of 209 students took part with females (70.8%) and males (29.2%). Age of participants ranges from 19-25 years. In this study female students have more knowledge and awareness regarding ZnO Sunscreen Protection compared to males. Among all the students Interns have more knowledge, followed by IV-BDS, III-BDS and II-BDS. Conclusion: The study result suggests that knowledge and awareness level of ZnO Sunscreen Protection is adequate.
CENTRAL SEROUS CHORIORETINOPATHY FOLLOWING ORAL USE OF TADALAFIL
Authors:   Ophtalmology A, Hopital des Specialites de Rabat., Hamza Lazaar , Sefrioui Meryem ,   Ophtalmology A, Hopital des Specialites de Rabat., Boutaj Taha ,   Ophtalmology A, Hopital des Specialites de Rabat., Tabchi Manal ,   Ophtalmology A, Hopital des Specialites de Rabat., Azarkan Boutayna ,   Ophtalmology A, Hopital des Specialites de Rabat., Abdelkader Akkoumi ,   Ophtalmology A, Hopital des Specialites de Rabat., Benchekroun Saad ,   Ophtalmology A, Hopital des Specialites de Rabat., Amazouzi Abdellah ,   Ophtalmology A, Hopital des Specialites de Rabat., Ouafa Cherkaoui Lalla ,   Ophtalmology A, Hopital des Specialites de Rabat.
Published: March 2024

Central serous chorioretinopathy (CSCR) is characterized by a localized serous detachment of the neuroretina (DSR), associated with detachments of the retinal pigment epithelium (RPE) at the posterior pole [1]and a leakage of fluid in the subretinal space. Pregnancy, Type A personality, and systemic corticosteroid therapy are the main risk factors for Central Serous Chorioretinopathy [ 2] We report the case of a patient who developed central serous chorioretinopathy following the oral intake of 20mg tadalafil erectile dysfunction, suggesting a possible involvement of phosphodiesterase type 5 inhibitors as a risk factor for central serous chorioretinopathy.
INFLUENCE DU PLASTIQUE RECYCLE DE TYPE POLYPROPYLENE SUR LES CARACTERISTIQUES DU BITUME ET DE LENROBE BITUMINEUX
Authors:   Institut National de la Recherche Scientifique (INRS), University of Lome 01BP1515 Lome 01 Togo., Abelim Passoli ,   Laboratoire National du Batiment et des Travaux Publics (LNBTP), B.P.20100 Lome Togo., Valerie Leleng Peacequeen Badaba ,   Laboratoire National du Batiment et des Travaux Publics (LNBTP), B.P.20100 Lome Togo., Sinko Banakinao ,   Laboratoire de Structure et Mecanique des Materiaux (LaS2M), University of Lome, 01BP1515 Lome 01 Togo., Yawovi Mawuenya Xolali Dany Ayite ,   Laboratoire de Recherche en Sciences de lIngenieur (LARSI), Ecole Polytechnique de Lome, University of Lome, 01BP1515 Lome 01 Togo.
Published: March 2024

Asphalt is the most widely used product in the construction of flexible pavements. The purpose of this study is to evaluate the feasibility of incorporating recycled polypropylene plastic into bitumen to obtain modified asphalt to manufacture modified asphalt mixes that offer better properties than conventional asphalt mixes. A type of asphalt mix has been studied, a semi-grained asphalt concrete (SGAC14). Conventional asphalt mixes as well as asphalt mixes containing 2% and 4% of the polypropylene dosages were manufactured. For all the tests carried out, the performance was evaluated according to five criteria: 1) improvement of the rheological properties of the bitumen (ring balls, penetrability, softening point, ductility) 2) suitability for compaction with the gyratory shear press (GCP) 3) Water resistance 4) rutting resistance and 5) the Marshall Trial. The experimental results showed, among other things: an improvement in the rheological properties of the modified bitumen for the respective polypropylene assays of 1%, 2%, 3%, 4% and 5%. For these assays, respectively, penetrability decreased by 29%, 37%, 42%, 74%, and 90% the temperature of beads and rings increased by 0.73%, 2.94%, 5.5%, 6.24% and 9.17% the springback increased by 13.82%, 21.40%, 5.69% and 4.07%. . The modified asphalt mixes with 2% and 4% polypropylene compact better than the reference asphalt at 80 gyrations with respectively 5.5% and 5.1% voids we have 6.1% voids for the reference asphalt. An increase in water resistance for polypropylene dosages at 2% and 4% respectively the latter offer a variation in simple dry compressive strength of 4.84%, 22% and a variation in compressive strength after 7 days of immersion in water of 8.53%, 19.5%. Improved rutting performance of modified asphalt mixes: The SGAC14 class 0 reference asphalt mixes are upgraded to a class 1 and class 2 SGAC0/14 for 2% and 4% polypropylene dosages respectively. Modified asphalt mixes give the best Marshall stability. Overall, the possibility of incorporating polypropylene into SGAC14 type asphalt has been proven.
Voces de lo invisible. Comisarías de familia y casos de violencias de pareja
Authors:   ESAP, Bernal Olarte Angelica , Gutierrez Martha Liliana ,   Universidad de Bogotá Jorge Tadeo Lozano
Published: March 2024

Voces de lo invisible recopila textos que abordan la relación entre las representaciones del amor romántico y la perpetuación de la violencia en pareja; la relación entre la violencia contra las mujeres ejercida por sus parejas o exparejas; la interacción de factores que llevan a la normalización de estas violencias; la reproducción de violencias al interior de las propias comisarias y el impacto en la vida cotidiana de las mujeres de debilidades institucionales de las comisarías, en contextos de recursos escasos.
Optimizing semantic error detection through weighted federated machine learning: A comprehensive approach
Authors:   School of Computer Science, National College of Business Administration and Economics, Lahore, Pakistan, Naz Naila Samar , Abbas Sagheer ,   School of Computer Science, National College of Business Administration and Economics, Lahore, Pakistan, Khan Muhammad Adnan ,   School of Computing, Skyline University College, Sharjah, UAE,   Department of Software, Faculty of Artificial Intelligence and Software, Gachon University, Seongnam, South Korea,   Riphah School of Computing and Innovation, Faculty of Computing, Riphah International University, Lahore, Pakistan, Hassan Zahid ,   School of Computer Science, National College of Business Administration and Economics, Lahore, Pakistan, Bukhari Mazhar ,   Department of Computer Sciences, The Institute of Management Sciences, Lahore, Pakistan, Ghazal Taher M. ,   Center for Cyber Security, Faculty of Information Science and Technology, Universiti Kebangsaan Malaysia (UKM), Bangi, Malaysia,   Applied Science Research Center, Applied Science Private University, Amman, Jordan
Published: March 2024

Recently, the improvement of network technology and the spread of digital documents have made the technology for automatically correcting English texts very important. In English language processing, finding and fixing mistakes in the meaning of words is a very interesting and important job. It is also important to fix wrong data in cleaning data. Usually, systems that find errors need the user to set up rules or statistical information. To build a good system for finding mistakes in meaning, it must be able to spot errors and odd details. Many things can make the meaning of a sentence unclear. Therefore, this study suggests using a system that finds semantic errors with the help of weighted federated machine learning (SED-WFML). This system also connects to the web ontology's classes and features that are important for the area of knowledge in natural language processing (NLP) text documents. This helps identify correct and incorrect sentences in the document, which can be used for many purposes like checking documents automatically, translating, and more. During its training and checking stages, the new model identified correct and incorrect sentences with an accuracy of 95.6% and 94.8%, respectively, which is better than earlier methods.
Identification of resistance to ramulosis caused by Colletotrichum gossypii var. cephalosporioides in cotton advanced breeding lines and monitoring of ramulosis disease by RGB-image analysis
Authors: Burbano Figueroa Oscar , Moreno Moran Milena , Osorio Almanza Lorena , Montes Mercado Karen , Vergara Enrique , Rodriguez Pinto Maria Del Valle , Salazar Keyra , Mosquera Everto
Published: March 2024

Identification of resistance to ramulosis caused by Colletotrichum gossypii var. cephalosporioides in cotton advanced breeding lines and monitoring of ramulosis disease by RGB-image analysis Abstract Cotton growing regions in South America are affected by Colletotrichum gossypii var. cephalosporioides (Cgc). The most severe epidemics provokes considerable yield reductions linked to meristem necrosis, oversprouting, excessive branching and stunting (Figure 1). The Sinu Valley is a major cotton producer in Colombia and is heavily affected by this disease. Rainfall was identified as the main driver of ramulosis development in the Sinu Valley prevailing in crops planted at the beginning of the main rainy season (Figure 2). Fifty five advanced breeding lines (ABLs) were assessed by ramulosis field resistance. Nine ABLs exhibited high levels of partial resistance (< 10% of plants exhibiting oversprouting). With the aim to optimize disease assessing accuracy and breeding efforts for ramulosis resistance, we had evaluated the use of red-green-blue (RGB) based indices for automated assessment of ramulosis disease. Eleven cultivars exhibiting contrasting level of ramulosis resistance were grown and photographed at different phenological stages. RGB indices extracted by Breedpix software from these plot images were compared with visual assessment of plant disease severity. The RGB indices Hue, Saturation, b, and v measured ten weeks after planting (boll opening) were correlated with accumulated disease severity and oversprouting (estimated as the area under the disease progress stairs). Oversprouting exhibited the higher correlation coefficients (r = 0.60,-0.65,-0.65,-0.60 and 0.54, P < 0.001). Additionally, destructive sampling across phenological development showed that green area (GA) has a positive correlation with total fresh biomass, leaf area index, leaf fresh biomass and green cover (GC) (r = 0.65, 0.60, 0.70 and 0.95, P < 0.001). RGB-based indices are appropriate predictors of cotton growth and ramulosis severity and a cost effective tool for cotton phenotyping based on automation of RGB-images assessment and affordable cost of RGB-cameras
Caracterización del crecimiento y rendimiento de la canal en cerdos de la raza criolla San pedreño en Antioquia
Authors: Hernández Ortiz Byron A. , Tobón Castaño Jaime A. , Ocampo Gallego Ricardo J. , Martínez Oquendo Piedad Y.
Published: March 2024

Actualmente existe el peligro de la inminente desaparición de las razas porcinas criollas colombianas, debido al reducido número de individuos, por lo tanto, se hace obligatorio realizar programas de conservación y caracterización de este recurso animal. Para ello, se registró el crecimiento y se evaluaron parámetros productivos en la canal de 16 cerdos criollos San pedreños pertenecientes al Banco de Germoplasma Animal de la Nación Colombiana administrado por Corpoica en el Centro de Investigación El Nus, municipio de San Roque - Antioquia.
Balanço de gases de efeito estufa (GEE) em Argissolo Vermelho (Acrisol) sob sistemas de cultura emplantio direto (PD)
Authors: Chavez Luis Fernando , Bayer Cimélio
Published: March 2024

El aumento en la concentración de gases de efecto invernadero (GEI) en la atmósfera está relacionado con el uso agrícola del suelo, que ha sido responsable, al menos en parte, del calentamiento global. Se realizaron dos estudios en experimentos a largo plazo (24 y 26 años) con labranza cero y sin adición de N mineral en un Acrisol, y cuyo objetivo es evaluar el efecto del manejo del suelo que incluye leguminosas y pastos con maíz en sucesión [avena / maíz (O / M), veza / maíz (V / M), avena + veza / maíz (O + V / M), avena + veza / maíz + caupí (O + V / M + C) y lablab + maíz (LL + M)], sobre las emisiones de GEI en el sur de Brasil.
Cadena de aguacate : anexo 5
Authors: González Cerón Sandra Paola , Pavas César , Osorio Jairo Antonio
Published: March 2024

El presente documento se preparó con el fin de proveer información básica sobre el desempeño de la cadena productiva, sus vínculos con la orientación de la ciencia, la tecnología y la innovación y las demandas del sector sobre conocimiento técnico, para superar problemas productivos, mejorar la competitividad, la sostenibilidad, aprovechar oportunidades de mercado, potenciar capacidades y focalizar la inversión pública. Esta información se consolidó a través del proceso de revisión y ajuste de la Agenda Dinámica Nacional de Investigación, Desarrollo Tecnológico e Innovación (Agenda I+D+i), como insumo para orientar las estrategias del PECTIA
Webcam-Based Bus Passenger Detection System Using Single Shot Detector Method
Authors: Wasista Sigit
Published: March 2024

Buses are one of the most widely chosen transportation methods to support the mobility of the Indonesian people. Mobility that is often found in addition to public transportation, is also often found in the mobility of tourism tour activities for a travel group. The number of tourist destinations to which passengers go up and down makes the assistant bus driver or group leader work hard to ensure that the number of passengers boarding the bus matches the number of groups. It often takes a long time to ensure the accuracy of the number of passengers before departure to the next destination. This conventional method results in the delay of the tourism tour schedule. In this research, the author designs a webcam-based bus passenger face detection system using the Single Shot Detector (SSD) method that can provide real-time information to bus drivers, assistant bus drivers or group leaders. The results obtained by the system obtained an achievement of 95% of the total system creation along with testing the detection of bus passenger faces in actual conditions resulted in an average accuracy of 77.5%.
DEVELOPMENTS AND TRENDS IN CYBERSECURITY AGAINST HUMAN FACTORS AND TIME PRESSURE USING BIBLIOMETRIC ANALYSIS
Authors: Saputri Aprilia Mayang , Syaifullah Syaifullah
Published: March 2024

Memahami keamanan siber sangat penting di era digital saat ini, dan penelitian telah dilakukan untuk memahami faktor-faktor yang mempengaruhi keberhasilan atau kegagalannya. Faktor manusia berperan penting dalam keamanan siber, dan lebih dari 95% serangan yang berhasil disebabkan oleh kesalahan manusia. Tekanan waktu adalah faktor lain yang tidak boleh diabaikan, karena organisasi sering kali menghadapi tekanan waktu yang tinggi dalam lingkungan bisnis yang kompetitif dan dinamis. Penelitian mengenai faktor manusia dalam keamanan siber menunjukkan bahwa faktor manusia masih menjadi perhatian utama dibandingkan dengan teknologi. Penelitian ini bertujuan untuk menganalisis perkembangan dan tren keamanan siber mengenai faktor manusia dan tekanan waktu dari tahun 2014 hingga 2023 menggunakan Analisis Bibliometrik dari software R studio. Metodologi penelitian meliputi perencanaan, identifikasi kata kunci, pencarian data Scopus, dan pembatasan pencarian pada "semua bidang" untuk memperoleh data yang sesuai dengan tema penelitian. Penelitian dibatasi sebanyak 110 jurnal yang diambil dari database Scopus. Kesimpulannya, memahami faktor manusia dan tekanan waktu dalam keamanan siber sangat penting bagi organisasi untuk meningkatkan langkah-langkah keamanan siber mereka. Dengan menganalisis perkembangan dan tren faktor-faktor ini, para peneliti dapat lebih memahami masa depan keamanan siber dan mengambil keputusan yang tepat untuk melindungi informasi dan infrastruktur penting.
Research on Application Solutions of Blockchain Technology in Multi-Party Collaborative Emergency Logistics System
Authors: Cheng Fan , Wei Xin
Published: March 2024

With the continuous development of global trade and logistics business, the construction of emergency logistics system has become an important part to ensure the efficient operation of logistics chain. However, in the face of emergencies, such as natural disasters, traffic accidents or public health crises, the traditional emergency logistics system is vulnerable to information asymmetry, data tampering and other problems, resulting in low emergency response efficiency. Blockchain technology, with its decentralized, immutable, transparent and traceable characteristics, offers new possibilities for solving these problems. This paper aims to discuss the solution of blockchain technology applied in the field of emergency logistics from the perspective of supply chain, in order to build a multi-agent collaborative emergency logistics “digital platform” network, and improve the response ability and toughness of the urban emergency logistics system that “combines emergency and peace”.
Errores de la Suprema Corte de Justicia de la Nación en derecho de los tratados
Authors: Rojas Amandi Víctor Manuel
Published: March 2024

El análisis de la aplicación de la Convención de Viena sobre Derecho de los Tratados (CVDT) y de la Convención de Viena sobre el Derecho de los Tratados entre Estados y Organizaciones Internacionales o entre Organizaciones Internacionales (CVDTOI) por la Suprema Corte de Justicia de la Nación durante el presente siglo, nos muestra que el máximo Tribunal del país ha incurrido en varios errores que van desde la confusión de la denominación de tales convenciones, pasando por las inexactas interpretaciones de sus disposiciones por cuanto hace a las definiciones de sus ámbitos materiales y espaciales de validez y terminando en una desorientada definición del sentido del artículo 46 de la CVDT.
control de convencionalidad y la cultura jurídica interamericana: hacia la construcción de un sentido colectivo
Authors: Martínez Neira Santiago
Published: March 2024

El control de convencionalidad tiene potencial para promover la implementación efectiva de la Convención Americana sobre Derechos Humanos (CADH). Sin embargo, la aplicación de esta herramienta y la apropiación de estándares interamericanos no ha sido pacífica entre jueces domésticos. En este articulo me enfoco en la idea de divergencias interpretativas como uno de los principales retos que enfrenta la implementación efectiva de la CADH. A partir del análisis de 4 decisiones sobre la prisión preventiva y las restricciones a los derechos políticos en Colombia, la reelección presidencial indefinida en Bolivia, y la interrupción voluntaria del embarazo en Argentina, demuestro que existen divergencias entre jueces domésticos respecto de los estándares desarrollados por la Corte IDH, y divergencias entre jueces domésticos y la Corte IDH respecto de la interpretación de la CADH. Para alivianar estas tensiones y potencializar el control de convencionalidad propongo que se debe promover una cultura jurídica interamericana que, a partir del diálogo judicial y la construcción de un sentido común, considere que la legitimidad de las normas y de las decisiones judiciales deviene, especialmente, de su compatibilidad con la CADH y los desarrollos de la Corte IDH. De esta manera, se puede lograr mayores consensos y escrutinio, mejores decisiones, y que las y los jueces de la región sean ‘jueces interamericanos’.
Absolute Liability Merits Demerits – A Critical Analysis
Authors: Singla Aman
Published: March 2024

In numerous circumstances, an individual is found liable for an act that he could not have performed, or for which he made all reasonable efforts to avoid causing any harm, yet was nevertheless held liable. This is a situation in which an individual is held liable notwithstanding the absence of fault; these are strict liability rules. The legislation recognises this provision based on the 'no-fault responsibility' criteria. These rules are based on case law. This clause was handed down in the case of Rylands vs. Fletcher, and hence this rule is commonly referred to as the "Rule in Rylands vs. Fletcher," however the rule of absolute A number of exceptions to this rule were established, and responsibility was established for them. The Supreme Court of India decided in M.C. Mehta vs. Union of India that the defendant is responsible for the act and that the offence should not be disputed. In tort law, the phrases strict liability and absolute liability must be defined. These two have a similar meaning, however there are some variances.
PENGUNGKAPAN DIRI ANTARA REMAJA JAWA DAN MADURA
Authors: Nabilah Masturah Alifah
Published: March 2024

Kebudayaan yang merupakan produk dari budaya memiliki pengaruh dalam pengungkapan diri seseorang. Tiap-tiap masyarakat dengan corak budaya masing-masing memberikan aturan tertentu atas individu pantas atau tidak pantas mengungkapkan diri. Suku Jawa dan Madura memiliki nilai-nilai budaya yang digunakan sebagai pedoman menjalani kehidupan sehari-hari. Tujuan penelitian ini adalah mengetahui perbedaan pengungkapan diri antara remaja Jawa dan Madura. Penelitian ini merupakan penelitian kuantitatif. Sampel adalah mahasiswa yang berusia antara 17-22 tahun berjumlah 50 orang suku Jawa dan 50 orang suku Madura. Pengambilan sampel dengan tehnik accidental sampling (non probability sampling). Metode pengumpulan data yang digunakan adalah skala Thurstone, yaitu skala pengungkapan diri. Adapun metode analisa data yang digunakan adalah t-test. Hasil penelitiaan menunjukkan terdapat perbedaan yang signifikan (t= -10.966; p= 0.000) pengungkapan diri antara remaja Jawa dan Madura. Remaja Madura memiliki tingkat pengungkapan diri yang lebih tinggi (3.1394) dibandingkan dengan remaja Jawa (2.7466).   Kata kunci: Pengungkapan diri, Remaja Jawa dan Madura.   Culture is a product have an influence in the disclosure of a person. Each community with cultural patterns each providing specific rules for individual worth or not worth expressing themselves. The Javanese and Madura who have cultural values ​​that are used as a guide through daily life. The purpose of this study was to determine the differences between adolescent self-disclosure of Java and Madura. The study is a quantitative research. Sample of this study were students Muhammadiyah University of Malang, aged between 17-22 account 50 Javanese and Madura people. Accidental sampling using sampling techniques (non-probability sampling).  Data collection methods used are the Thurstone scale, the scale of self-disclosure. The data analysis method used is the t-test. Based on theoretical studies and research conducted by the researchers that the hypothesis which states there is a difference between adolescent self-disclosure of Java and Madura received. From the results of the study, data showed that there are significant differences (t = -10 966, p = 0.000) between adolescent self-disclosure of Java and Madura.Madura adolescents have high levels of self-disclosure is higher (3.1394) compared with adolescents Java (2.7466).   Keyword : Self disclosure, Adolescence Java and Madura
TINGKAT KECEMASAN PADA SANTRI PONDOK PESANTREN
Authors: Novalia Siregar Chynthia
Published: March 2024

Kecemasan merupakan salah satu kekhawatiran terbesar yang dialami oleh semua individu. Kecemasan ini menghasilkan hal negatif di berbagai aspek kehidupan, khususnya pada aspek akademis. Penelitian ini merupakan penelitian non-eksperimen deskriptif kuantitatif bertujuan untuk mengetahui tingkat kecemasan pada santri Pondok Pesantren. Sampel penelitian ini sebanyak 78 orang santri Pondok Pesantren Nurul Huda Singosari Malang dengan menggunakan Taylor Manifest Anxiety Scale (TMAS) yang terdiri dari 50 item. Analisis penelitian menggunakan Z-Score. Berdasarkan analisis ditemukan bahwa sebesar 14,1% atau 11 santri mengalami kecemasan dengan tingkat tinggi. Sementara yang mengalami tingkat kecemasan sedang  sebesar 66,7% atau 52 santri dan sisanya sebesar 19,2% atau 15 santri mengalami tingkat kecemasan rendah. Kata kunci: Kecemasan, Santri pondok pesantren     Anxiety is one of the biggest worries experienced by all people. Anxiety produces negative in many aspects of life, especially in the academic aspect. This research is a quantitative non-experimental descriptive aims to determine the level of anxiety on the male boarding school. The sample as many as 78 people Nurul Huda Islamic boarding school students Singosari Malang using the Taylor Manifest Anxiety Scale (TMAS) consisting of 50 item. Analysis of studies using the Z-Score. Based on the analysis it was found that 14.1% or 11 students with a high level of anxiety. While experiencing the anxiety level was at 66.7% or 52 students, and the remaining 19.2% or 15 students experienced low levels of anxiety. Keywords: Anxiety, Boarding school student
TRANSTORNO DEPRESSIVO E DOENÇA FALCIFORME: O estado da arte
Authors: Camargo Laura Carvalho de , Camargo Natália Carvalho de , Costa Luiz Henrique Alves , Lucena Julia Bettencourt , Silva Maria Sebastiana , Sousa Romes Bittencourt Nogueira de
Published: March 2024

The connection between sickle cell disease and depression, although crucial, remains an inadequately explored field, calling for further investigation. This notably concerning health scenario demands more specialized attention from professionals in the field. The present study aims to meticulously analyze the relationship between sickle cell disease and depression, delving into the state of the art on this subject, incorporating sources such as articles, books, dissertations, and theses. Individuals with sickle cell disease show a propensity for elevated levels of depression compared to the general population. Additionally, it has been observed that patients with sickle cell disease and depression experience an intensification of pain compared to their counterparts without depression, suggesting an intrinsic correlation between pain and both conditions. The in-depth analysis of the pathophysiology of both sickle cell disease and depression played a fundamental role in understanding this interconnection. It is concluded that the quality of life for these individuals is compromised, not only in terms of pathophysiological aspects but also in the realms of mental health, highlighting a significant increase in morbidity associated with the presence of depression. In this context, seeking medical assistance proves crucial to mitigate the impacts on the mental health of individuals with sickle cell disease, emphasizing the need for a holistic and integrated approach to substantially improve their quality of life.
На пути к сбалансированному пространственному развитию Российской Федерации
Authors: Герцберг Лора
Published: March 2024

Пространственная политика РФ анализируется на фоне глобальных тенденций урбанизации, появления новых, расширения и слияния существующих агломераций. Рассматриваются два её основных направления. Первое – поддержка и содействие развитию крупных агломераций РФ на основе заключения договоров с прилегающими к агломерациям муниципальными образованиями внутри региона, а также с приграничными муниципалитетами соседствующих регионов и образование на этой основе межрегиональных агломераций. Второе – сдерживание разрушения каркаса сельского расселения путём формирования в каждом регионе двадцати опорных центров расселения с 50-километровыми зонами их влияния. Основная цель сформулирована как обеспечение сбалансированного устойчивого развития. Отмечается, что внимание, которое в последнее время уделяется развитию малых городов и сельских поселений, повышению качества их среды проживания как в политике, так и в высказываниях представителей власти, свидетельствует о тенденции либерализации пространственной политики. Вместе с тем отсутствуют научные и проектные проработки реализации этой политики. Нет схем организации рас-селения, расчётов требуемого и реального финансового обеспечения. Поставлено множество задач и определено большое количество приоритетов на короткий промежуток времени до 2025 и 2030 годов. Недостаточно учтены факторы, влияющие на создание межрегиональных агломераций, как-то: сокращение и постарение населения, наличие огромных пустующих пространств между городами, надвигающийся экономический кризис, рост природных катаклизмов. Всё это ставит под сомнение реальность выполнения ряда основных задач, в том числе сдерживание разрушения сельского расселения, выравнивание качества среды проживания. Но процесс финансирования в опережающем порядке начался.
Образ крепости в составе русских загородных ансамблей середины XVIII века
Authors: Башкирова Мария
Published: March 2024

Статья посвящена утраченным памятникам середины XVIII века, которые находились в составе архитектурно-парковых ансамблей в окрестностях Санкт-Петербурга и Москвы. Все эти сооружения принадлежали к стилю позднего барокко и рококо и являлись парковыми увеселительными павильонами, но их планы и объёмно-пространственные решения воспроизводили облик военной крепости. В статье предпринята попытка рассмотреть эти постройки как целостное явление в истории русской архитектуры Нового времени.
Дом Фредерикса в застройке ансамбля императорской Ливадии
Authors: Слюнькова Инесса
Published: March 2024

Статья направлена на устранение лакуны знаний о ценных объектах историко-культурного наследия начала XX века. Дом Фредерикса является одним из основных памятников архитектуры Ливадии, хотя историко-архитектурное исследование проводится впервые. Раскрывается его художественное значение, место и роль в системе императорского дворцово-паркового ансамбля. Выделяются ключевые вопросы: соответствие планировки и композиции назначению здания и требованиям заказа, поиски художественного образа и работа над вариантами фасадов, особенности стиля. Оригинальные приёмы архитектуры здания, отражение в ней индивидуальности заказчика проявляются благодаря документальной реконструкции замысла строительства, анализу чертежей проекта. Вводятся новые архивные письменные источники, публикуются неизвестные ранее графические материалы по проекту архитектора А.А. Бибера.