bluuebunny/crossref_metadata_2025 huggingface dataset:
Sobre la Naturaleza de las Causas de Justificación a la Vista de la Discusión Acerca de la Exigencia de un Elemento Subjetivo
Authors: Fernández Perales Francisco
Published: November 2024

La discusión acerca de si las causas de justificación deben confi­gurarse o no con un elemento subjetivo ha estado marcada por el paradigma del necesario paralelismo entre fundamentación y exclusión del injusto. Sin negarlo, en este trabajo se propone un nuevo enfoque, que parte de la distin­ción entre antijuridicidad objetiva e injusto penal –antinormatividad ex ante merecedora de pena–, categorías a las que se vinculan, respectivamente, las causas de justificación (general) y las causas de exclusión del injusto penal (o del merecimiento de pena). La referida distinción implica que un elemento subjetivo solo pueden contenerlo estas últimas.
Argument z postmodernizmu. Epizod z wojny twórców z krytykami
Authors: Sunderland Daniel
Published: November 2024

W artykule przeanalizowano spór reżyserki Barbary Białowąs z recenzentem Michałem Walkiewiczem w kontekście innych przypadków, w których postmodernizm miał służyć za tarczę chroniącą przed ostrzem krytyki (Siostra Małgorzaty Saramonowicz, Lubiewo Michała Witkowskiego, Agent Manueli Gretkowskiej). Tekst kończy się rozważaniem: czy hasło „postmodernizm” wciąż jeszcze cokolwiek znaczy, czy może stanowi już tylko prosty chwyt erystyczny?
Legislative Regulation of Territorial and Organizational Foundations of Local Government in the Villages of the Republic of Türkiye
Authors: Bykova A. G.
Published: November 2024

The study focuses on analyzing Turkish national legislation regarding the territorial and administrative structure of local governance. The relevance of this research stems from the limited exploration of this subject within domestic legal studies. This article is based on the national Turkish legislation, presented in the Author’s translation. The Author describes the legal framework governing local government in Türkiye’s villages, with particular emphasis on the structure and organization of local governance. The analysis of local government legislation was conducted to achieve several aims: first, to identify the territorial structure of local governance; second, to define the local governance system at the lowest level of public authority, specifically in villages; and third, to clarify the legislative delineation of the roles and responsibilities of local governance bodies and officials. The study explores both the foundational and evolving territorial and administrative principles underpinning local governance in Türkiye, highlighting their resilience and effectiveness, which have endured for over a century. The article draws attention to attempts at reforming these territorial and administrative foundations in line with Türkiye’s broader state development goals. The Author employs general, specialized, and specific scientific methods, including formal-logical, historical-legal, analysis and synthesis, abstraction, and problem-chronological methods, to provide a comprehensive overview of Turkish legislation, examine its evolution, and draw conclusions. Notably, the study identifies a direct correlation between the issues facing rural municipalities and Türkiye’s territorial governance structure, which is, in turn, shaped by the country’s administrative-territorial organization. An analysis of Türkiye’s local governance system throughout the 20th and early 21st centuries illustrates a hybrid model of local governance.
Codification of Norms on Judicial Consideration of Cases on Administrative Offenses: Experience of 16 Neighboring Countries
Authors: Schepalov S. V.
Published: November 2024

The article discusses the evolution of legislation concerning the judicial review of administrative offense cases across post-Soviet countries. It concludes that the Fundamentals of the Legislation of the USSR and the Union Republics on Administrative Offenses, adopted in 1980, represented only a partial codification of administrative-procedural norms. However, this legislative act established a tradition of fully codifying administrative tort and related procedural laws, merging judicial and non-judicial processes for handling administrative offense cases into a unified proceeding. In the post-Soviet period, despite this legacy, nearly all neighboring countries have seen a consistent trend of judicial proceedings separating from non-judicial ones in the realm of administrative offenses. Integrating judicial procedures into the administrative procedure code is an exception rather than a rule; instead, these procedures often resemble criminal proceedings, sometimes even referencing criminal procedure codes. Nevertheless, even within the administrative-jurisdictional system, judicial procedures increasingly diverge from non-judicial ones, either evolving into separate procedural institutions or prevailing as the primary procedural framework. In this context, the Author aligns with the views of Yu. P. Solovey and P. P. Serkov, who argue that proceedings on administrative offenses are distinct from public-law dispute resolution, and that judicial consideration of administrative offenses differs fundamentally from non-judicial administrative-jurisdictional activities. Consequently, the article concludes that judicial and non-judicial reviews of administrative-tort cases do not form a single, cohesive administrative offense proceeding. Anticipating future developments in Russian legislation, based on comparative legal analysis, the Author suggests that the adoption of a Procedural Code on Administrative Offenses may serve only as a temporary measure. In the near future, the need to establish a separate procedural law governing administrative offense cases in courts of general jurisdiction may arise.
Criminal-Legal, Criminological, and Forensic Aspects of the Public Demonstration of Crimes Against Individuals on the Internet
Authors: Pestereva Yu. S. , Timoshenko S. E.
Published: November 2024

This article examines the criminal-legal, criminological, and forensic characteristics, as well as specific investigative aspects, of “trash streams” – online broadcasts that display the commission of crimes. These streams contain criminologically significant information and promote unlawful behavior, making the actions of individuals involved in such broadcasts subject to criminal and forensic analysis. It is concluded that current criminal law does not establish separate liability for trash streams; within the framework of existing legislation, there has only been an intensification of criminal responsibility for already established crimes against individuals. In attempts to impose specific liability for trash streams, legislators have not adequately addressed the criminal motives of the perpetrators or the role of “viewers” of these streams. However, complicity provisions allow law enforcement to consider these viewers as accomplices or instigators. The Authors argue that in cases of live broadcasting of illegal actions as specified under Articles 105, 111, 112, 117, 119, 126, 127, 1271 , and 1272 of the Criminal Code of the Russian Federation, it is appropriate to consider the context of the crime’s commission. Meanwhile, the broadcast of recordings of these crimes should be treated as criminalized post-crime behavior. In both scenarios, public morality serves as an auxiliary object of this category of crimes.
The Place of Cybercrime
Authors: Sharapov R. D.
Published: November 2024

This article addresses the criminal-legal characteristics of the location of cybercrimes – offenses committed using electronic or information and telecommunications networks, including the Internet. The concept of the crime’s location in criminal and criminal procedural law is examined, including possible approaches to defining a unified concept of location, which is associated with specific legal consequences in criminal and criminal procedural law: sector-specific (focused on issues within a specific field) and cross-sectoral (aiming for a universal definition applicable across fields). It is noted that all approaches require defining the crime’s location based on legal fiction. This means the crime’s location is formally tied to the territorial localization of one of the crime’s elements (usually the place of action and/or the place of social harm). Based on the explanations provided by the Plenum of the Supreme Court of the Russian Federation and current judicial practice, it is concluded that both criminal and procedural law regard the crime’s location as determined by the time of its commission (as per Article 9, Part 2, of the Criminal Code of the Russian Federation). Therefore, the location of a crime is considered to be where the socially dangerous action (or inaction) occurred, regardless of where the consequences took place. The article also analyzes issues surrounding the determination of cybercrime locations, considering the complex design of their objective aspects. The location of a single cybercrime involving several illegal actions, separated in both time and space, should be considered the location of each action. Procedurally, such a crime is regarded as “initiated in one place and completed in another”, which affects jurisdiction based on the “place of completion” (interpreted in procedural, rather than criminal, terms). This is typically the place where the final act that constitutes part of the crime occurred (per Article 32, Part 2, and Article 152, Part 2, of the Criminal Procedure Code of the Russian Federation).
PEN teorija ličnosti u savremenom vaspitanju i obrazovanju
Authors: Genc Lajoš L.
Published: November 2024

U radu se razmatra mogućnost primene PEN teorije ličnosti koju su postavili Ajzenk i njegovi saradnici u savremenom vaspitanju i obrazovanju. Akronim PEN odnosi se na dimenzije ili faktore psihoticizma, ekstraverzije i neuroticizma uzduž kojih se mogu rasporediti nivoi ovih osobina ličnosti. Nakon detaljnog prikaza teorije i upitnika kojima je teorija operacionalizovana u različitim fazama njenog uobličavanja, opisane su određene mogućnosti primene ove teorije od strane današnjih aktera u vaspitno-obrazovnom radu. Data su i teorijska objašnjenja u vezi sa nastankom savesti i samodiscipline, opsesivno-kompulzivnih reakcija i fobija, te u vezi sa školskim postignućem i nekim aspektima nastave koja su izvedena iz PEN teorije. U zaključnim razmatranjima istaknute su i dodatne specifične karakteristike formulisanja ove teorije u odnosu na danas veoma uticajne petofaktorske i iz njih izvedene višefaktorske modele ličnosti.
Music Education in the Context of School Modernization in Croatia during the 19th century
Authors: Košta Tomislav
Published: November 2024

The aim of this paper is to demonstrate to what extent the legislative efforts for the modernization of the school system in Croatia during the 19th century influenced the development of music education in elementary schools. The need for the state to regulate education became increasingly pronounced during the 18th and 19th centuries, leading to the enactment of key legislative documents during the period that had a considerable effect on the school system, and as such served as a foundation upon which the modern education as we know it today was built. The importance of the documents analysed is observed not only through the lens of shaping the school system but also in the context of music education. This opened the door for music educators of various profiles to strive for the improvement of music teaching. Initially, music education was limited to singing activities, but soon debates emerged about whether singing was sufficient and whether other elements of music education should be incorporated into the curriculum. These debates are followed through publications in professional journals, as well as through the analysis of textbooks and teaching materials that were created and used in music education during the 19th century.
A review of hydrogen combustion and its impact on engine performance and emissions
Authors: Skobiej Kinga
Published: November 2024

The article focuses on the latest research and advancements in the use of hydrogen as a fuel for internal combustion engines. It provides an in-depth analysis of hydrogen's potential to improve combustion efficiency, especially when used in blends with fossil fuels like ammonia and methane. Key findings highlight hydrogen's ability to reduce harmful emissions such as CO, HC, and soot, though it can increase NOx emissions due to higher combustion temperatures. The article also reviews various hydrogen injection technologies, including direct injection, which outperforms port fuel injection by significantly enhancing power output and fuel efficiency. Moreover, the study emphasizes the need for optimizing hydrogen ratios in dual-fuel engines to balance performance and emissions. These insights underscore hydrogen's role in future decarbonization efforts, with ongoing research focusing on mitigating NOx emissions while maintaining high efficiency.
Peningkatan Pengetahuan Tentang DAGUSIBU pada Kader Kesehatan Desa di Desa Pagebangan, Kecamatan Karanggayam
Authors: Rahmatulloh Wahyu , Ainni Ayu Nissa , Miyarso Chondrosuro , Agustina Resti , Supartiningsih Sinta , Abrori Fadhil
Published: November 2024

Penyuluhan terkait program DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang Obat dengan Benar) sangat penting untuk meningkatkan pengetahuan masyarakat terutama di daerah pedesaan dengan akses terbatas terhadap informasi kesehatan. Penelitian ini bertujuan untuk meningkatkan pengetahuan kader kesehatan desa di Desa Pagebangan, Kecamatan Karanggayam, terkait penggunaan obat yang baik dan benar terutama selama bulan Ramadhan. Metode yang digunakan adalah ceramah dan diskusi interaktif yang diikuti oleh enam kader kesehatan desa. Evaluasi dilakukan melalui pretest dan posttest untuk mengukur peningkatan pengetahuan. Hasil penelitian menunjukkan bahwa adanya peningkatan signifikan dalam pengetahuan kader kesehatan dengan 83% kader masuk dalam kategori sangat baik dan 17% dalam kategori baik setelah pemberian edukasi. Peningkatan juga terlihat pada pengetahuan masyarakat yang seluruhnya masuk dalam kategori sangat baik setelah pelaksanaan sosialisasi oleh kader kesehatan. Kesimpulan dari pengabdian ini bahwa terdapat peningkatan pengetahuan setelah pemberian edukasi sehingga diharapkan dapat mengurangi kesalahan penggunaan obat dan meningkatkan derajat kesehatan masyarakat.Kata Kunci: DAGUSIBU, Kader Kesehatan, Kader DesaEducation related to the DAGUSIBU program (Get, Use, Store, and Dispose of Medicines Properly) is essential for improving public knowledge, especially in rural areas with limited access to health information. This study aims to enhance the knowledge of village health cadres in Pagebangan Village, Karanggayam Subdistrict, regarding the proper and correct use of medicines, especially during Ramadan. The methods include lectures and interactive discussions attended by six village health cadres. The evaluation was conducted through pretest and posttest to measure knowledge improvement. The results showed a significant increase in the knowledge of the health cadres, with 83% of cadres categorized as excellent and 17% as good after education. An improvement was also observed in the community's knowledge, with all participants categorized as excellent after the health cadres' outreach activities. This community service concludes that there was an increase in knowledge following education, which is expected to reduce medication errors and improve the health status of the community.
Role of Vitamin and Minerals Supplementation in Periparturient Dairy Cows
Authors: Bhimte Aamrapali
Published: November 2024

The transition stage is characterized by reduced dry matter intake, impaired liver function, and increased inflammation and oxidative stress. Which may increase the need for trace minerals and vitamin E. Trace elements are important for many important biological functions in dairy cows, including immunity, oxidative metabolism, nutrient, energy metabolism, and reproductive function. Selenium (Se) plays a role in the antioxidant system as a key component of the glutathione peroxides enzyme, which can remove hydrogen peroxide (H2O2) and lipid hydro peroxides. Vitamin E has a immunity booster effect in dairy cow. Copper (Cu) and zinc (Zn) are important components of several enzymes, including Cu-Zn superoxide dismutase (SOD) and redox processes. Manganese (Mn) is an important cofactor in enzymatic reactions related to metabolic regulation. Moreover, there is strong evidence that trace elements such as Se, Zn, Cu, and Mn can minimize the adverse effects of oxidative stress. Cows in subtropical and tropical regions are exposed to many stressors, including seasonal malnutrition, parasites and blood-sucking insects, high temperature, and high humidity. The maintenance of efficient milk production is of utmost importance and high reproductive performance is absolutely crucial. Biological adjustments are necessary to support dramatic production increase during post-partum in cow.
Soil-associated fungal and prokaryotic diversity influenced by stoniness, depth and vintage in a high-altitude vineyard
Authors: Mezzatesta Daniela , Oyuela Aguilar Mónica , Gobbi Alex , Pistorio Mariano , Hansen Lars Hestbjerg , Buscema Fernando , Piccoli Patricia , Berli Federico
Published: November 2024

Soil microbes are increasingly recognised as key contributors to wine terroir, playing crucial roles in soil health and nutrient cycling. Fungi and prokaryotes interact with soils, influencing physical and chemical properties and mediating nutrient availability for roots. These microorganisms also impact vine performance and wine quality. Viticulture is expanding to higher elevations due to their cooler temperatures; Mendoza's mountainous regions are of particular interest being, characterised by vineyards with heterogenous soil stoniness. However, the effect of this variability on soil-associated microbial communities remains unclear. This study explores microbial populations (alpha and beta diversity, taxonomical composition, and their relationship with soil physicochemical properties) in soils of contrasting stoniness, at different depths, vintages and sample types. A Malbec vineyard with heterogenous soil stoniness was selected, with two experimental sites 30 m apart containing stony soil (SS; 77 % stoniness) and non-stony soil (NS; 0 % stoniness), respectively, and which were managed identically. Samples were collected from two depths (0.3 m and 0.6 m) during two vintages (2017 and 2018), from bulk and rhizosphere. Amplicon sequencing targeted the V3-V4 region of the 16S rRNA gene (prokaryotes) and the ITS1 region (fungi). Results showed that soil type significantly influences fungal populations, with less effect on prokaryotes. Vintage, reflecting annual changes in weather and viticultural practices, was the most significant factor affecting microbial communities. Depth was particularly important for fungi, while the sampling type (bulk or rhizosphere) had no significant impact on the microbiome within the same soil profile. Certain soil components were found to influence microbial communities: pH affected prokaryotes, while calcareous content specifically influenced the Proteobacteria phylum. Additionally, five fungal orders were more abundant in the stony soils, though some remained unidentified. These findings provide a baseline for understanding microorganisms in contrasting soils types of a high-elevation vineyard, and they highlight the role of microbial diversity in supporting unique soil-plant-environment interactions.
Navigating the Human-Robot Interface – Exploring Humans Interactions and Perceptions with Social and Telepresence Robots
Authors: Mårell-Olsson Eva , Bensch Suna , Hellström Thomas , Alm Hannah , Hyllbrant Amanda , Leonardson Mimmi , Westberg Sanna
Published: November 2024

This study investigates user experiences of interaction with two types of robots: Pepper, a social humanoid robot, and Double 3, a self-driving telepresence robot. Conducted in a controlled setting with a specific participant group, this research aims to understand how different robot embodiments affect user perception, interaction patterns, and emotional responses. The findings underscore the role of adaptability, effective communication, autonomy, and perceived credibility in user-centered robot design. Despite limitations in sample size, the study provides insights into the ethical and social considerations of integrating AI in public and professional spaces, highlighting implications for enhancing user-centered design and expanding applications for Social and Telepresence robots in society.
The Impact of COVID-19 on DTP3 Vaccination Coverage in Europe (2012-2023)
Authors: Aguinaga-Ontoso Ines , Guillen-Aguinaga Sara , Guillen-Aguinaga Laura , Alas-Brun Rosa , Guillen-Aguinaga Miriam , Onambele Luc , Aguinaga-Ontoso Enrique , Rayón-Valpuesta Esperanza , Guillen-Grima Francisco
Published: November 2024

The COVID-19 pandemic disrupted routine child immunization efforts, threatening to reverse progress in controlling vaccine-preventable diseases. We analyzed the impact of COVID-19 on DTP3 vaccination in Europe by comparing trends before and after the pandemic using time series data from 2000 to 2023. Employing Joinpoint regression, chi-square tests, and segmented regression analysis, we assessed DTP3 vaccination trends and coverage changes. The findings revealed significant regional disparities across Europe. Statistical models indicated reductions in DTP3 coverage in countries like Ireland, Sweden, and Switzerland, whereas Ukraine and San Marino showed improvements. These variations indicate the need for targeted public health strategies to address vaccine hesitancy, logistical barriers, and systemic inequities.
Intelligent Multi-Channel Protocol for Improved UAV Surveillance Efficiency
Authors: Vavekanand Raja , Singh Vijay , Kumar Teerath , Roy Arunabha M.
Published: November 2024

In this work uses innovative multi-channel load-sensing techniques to deploy unmanned aerial vehicles (UAVs) for surveillance. The research aims to improve the quality of data transmission methods and improve the efficiency and reliability of surveillance systems by exploiting the mobility and adaptability of UAVs does the proposed protocol intelligently distribute network traffic across multiple channels, considering the load of each channel, While addressing challenges such as load balancing, this study investigates the effectiveness of the protocol by simulations or practical tests on The expected results have improved UAV-based surveillance systems, more flexible and efficient networks for applications such as security, emergency response and the environment alignment of monitoring -Offering infrastructures, which contribute to efficient and reliable monitoring solutions.
Procurement, Processing, And Storage Of Human Amniotic Membranes For Implantation Purposes In Non-Healing Pres-Sure Ulcers
Authors: Gómez Lina Andrea , Domínguez-Paz Carlos , Ospina Juan , Vargas Elga Johanna
Published: November 2024

The human amniotic membrane has (hAM) been used as implants to enhance the regenerative process and control inflammation in different disease given their structure, biocompatibility, presence of stem cells and multiple growth factors. The objective of this study was to generate a standardized protocol for obtaining, processing, and storing hAMs that guarantees the conservation of structural and cellular characteristics as well as its mechanical properties, ensuring its ease of handling, sterility, and quality that allows its implementation for therapeutic purposes in the field of regenerative medicine. The hAMs were obtained from mothers with healthy, full-term, controlled pregnancies and by cesarean section. The hAMs were processed under sterile conditions, manually separated from the placenta and subsequently, they were frozen in a solution of culture medium plus 50% v/v glycerol. The protocol allows obtaining sterile hAMs composed of both epithelium and stroma with adequate preservation of the amniotic cells. The glycerol's impact on the mechanical properties may enhance the membrane's adaptability and conformability to diverse wound surfaces, potentially improving the healing process. It´s necessary to repeat the microbiological, cell viability and mechanical studies at 6 and 12 months to ensure that long-term frozen conditions do not affect the quality of the hAMs.
ABCB1 Polymorphism Is Associated with Higher Carbamazepine Clearance in Children
Authors: Djordjevic Natasa , Cukic Jelena , Dragas Milovanovic Dragana , Radovanovic Marija , Radosavljevic Ivan , Vuckovic Filipovic Jelena , Obradovic Slobodan , Baskic Dejan , Milovanovic Jasmina R , Jankovic Slobodan , Milovanovic Dragan
Published: November 2024

Background/Objectives: The aim of our study was to investigate the role of ABCB1 polymorphism in pharmacokinetics of carbamazepine (CBZ) in children. Methods: The study enrolled 47 Serbian pediatric epileptic patients on CBZ treatment. Genotyping for ABCB1 1236C<T (rs1128503), 2677G<A/T (rs2032582) and 3435C<T (rs1045642) was carried out using TaqMan method. Steady-state CBZ serum concentrations were available from the previous study, determined by high pressure liquid chromatography (HPLC) method. NONMEM software and one-compartment model were used for pharmacokinetic analysis. Results: ABCB1 1236C<T, 2677G<A/T and 3435C<T variations were found at the frequencies of 47.9%, 48.9% and 52.1%, respectively. The equation that described population clearance (CL) was CL (l/h) = 0.175 + 0.0403*SEX + 0.0332*ABCB1 + 0.0176*CYP1A2 + 0.000151*DD where SEX has a value of 1 if male and 0 if female, ABCB1 has a value of 1 if C-G-C/T-T-T and 0 if any other ABCB1 diplotype, CYP1A2 has a value of 1 if −163A/A and 0 if −163C/C or C/A, and DD is the total CBZ daily dose (mg/day). Conclusions: The presence of ABCB1 1236T-2677T-3435T haplotype is associated with increased clearance of CBZ in pediatric epileptic patients.
Response of Pedunculate Oak (Quercus robur L.) to Adverse Environmental and Weather Conditions in Genetic and Dendrochronological Studies
Authors: Krutovsky Konstantin V. , Popova Anna A. , Yakovlev Igor A. , Yanbaev Yulai A. , Matveev Sergey M.
Published: November 2024

Pedunculate oak (Quercus robur L.) is widely distributed in Europe and plays a critical ecological role. Studying how it responds to stressors such as drought, extreme temperatures, pests and phytopathogen helps reveal the species' capacity to adapt to climate change. Genetic and dendrochronological data (tree-ring analysis) provide insights into historical resilience, a historical record of how trees have responded to past environmental stressors, revealing which traits and genetic variants are linked to climate adaptation and how they may contribute to future resilience in changing environments. By examining the width, density, and dynamics of tree rings in Q. robur, researchers can correlate periods of growth suppression or enhanced growth with specific environmental conditions. This information helps predict how forests might respond to future climatic events and supports conservation and management strategies. By identifying genetic markers associated with stress tolerance, forest managers can prioritize the conservation of populations with higher adaptive potential. This is particularly important as Q. robur is an economically and ecologically valuable species. One of the main objectives of the review to summarize also publications on Q. robur genetic diversity and adaptive traits that can guide reforestation efforts and help develop climate-resilient oak populations. The review is focused on genetic and dendrochronological studies that offer complementary perspectives on tree response mechanisms. Genetic studies reveal adaptive genetic diversity and inheritance patterns, while dendrochronology provides a phenotypic record of responses over time. Combining these fields creates a holistic understanding of how Q. robur responds to stress, useful for fields ranging from ecology to forest genetics. Hopefully, this review helps understand Q. robur's resilience mechanisms, support adaptive management practices, and enable sustainable forest planning in the face of environmental challenges.
Eco-Friendly Synthesis of Cerium Oxide Nanoparticles from Lycium cooperi
Authors: Castillo-Saenz Jhonathan , Salomón-Carlos Jorge , Beltran-Partida Ernesto , Valdez-Salas Benjamin
Published: November 2024

Cerium oxide nanoparticles (CeO2-NPs) have suggested promising advantages in semiconductors and biomedical applications due to the provided optical, electrical, antioxidant, and antibacterial activity. However, the widely reported synthetic strategies for CeO2-NPs demand toxic precursors and intermediary pollutants that represent a severe limitation in CeO2-NPs applications. Therefore, it is required to develop greener strategies that implicate ecological precursors to reduce the negative impact on the scalability of CeO2-NPs. In this regard, we applied Lycium cooperi (L. cooperi) aqueous extracts as an unexplored potential green reducing agent for the eco-friendly synthesis of CeO2-NPs. The L. cooperi extract showed the presence of alkaloids, flavonoids, cardiac glycosides, and carbohydrate-derived families that were assessed for spherical monodispersed CeO2-NPs under a rapid chemical reduction. Moreover, the elemental composition displayed Ce and O, indicating a high pure CeO2-NPs characterized by an interplanar cubic crystalline structure. Furthermore, we detected the presence of stabilizing functional groups from L. cooperi, which after a controlled annealing process, resulted in a band gap energy of 3.9 eV, which was optimal for CeO2-NPs. Thus, the results proposed L. cooperi as an environmentally friendly synthesis method that can open a new route for CeO2-NPs in biomedical and industrial applications.
Title: Bone Loss Associated with Extraction of Impacted Third Molars: A Literature Review and Meta-Analysis
Authors: Kaleci Shaniko , Bellini Pierantonio , Setti Giacomo , Melloni Giulia , Ruozzi Matilde , Consolo Ugo
Published: November 2024

Background: The extraction of impacted third molars presents anatomical challenges and surgical risks, prompting debate over prophylactic removal, particularly for impacted lower molars.
Types of Studies Reviewed: This meta-analysis was conducted according to PRISMA guidelines, included studies from 2000 to 2024. This meta-analysis examined the relationship between the mesioangular position of impacted third molars and pathological changes, including bone loss adjacent to the second molar.
Results: Of the 2943 studies initially identified, 10 studies (2163 patients) met the inclusion criteria, 4 studies included in the meta-analysis. Statistical analysis revealed that horizontally impacted third molars showed a higher percentage of pathological change (41%) compared to vertically (20.7%), mesioangular (21.4%), and distoangular (9.7%) molars. Additionally, cystic degeneration and bone loss distal to the second molar were frequently observed, with increased incidence in patients aged 20-25. Significant heterogeneity among studies was noted, and a need for consistent monitoring of impacted third molars was recommended.
Practical Implications: The findings suggest that impacted third molars, even when asymptomatic, pose a risk for adjacent structures and warrant careful evaluation. Routine imaging and close monitoring of follicular and bone changes may enhance preventive care, particularly for horizontally impacted third molars with higher rates of pathological changes.
Two-Dimensional MoS2-Based Photodetectors
Authors: Ye Leilei , Gan Xiaorong , Schirhagl Romana
Published: November 2024

Nanomaterials used can significantly improve the analytical performance of optical sensors to environmental pollutants. Two-dimensional (2D) molybdenum sulfide (MoS2) exhibits some unique physicochemical properties such as strong light-matter interaction, bandgap tunability, and high carrier mobility, which are beneficial for constructing flexible optoelectronic devices. In this Review, the principle and classification of 2D MoS2-based photodetectors (PDs) are introduced, followed by a discussion about the physicochemical properties of 2D MoS2, as well as structure-property relationships of 2D MoS2-based photoactive materials for PDs to understand the modulation strategies for enhancing the photodetection performance. Furthermore, we discuss significant advances in the surface modification and functionalization of 2D MoS2 for developing high-performance PDs, particularly focusing on synthesis pathways, modification strategies, and underlying physiochemical mechanisms for enhanced photodetection capabilities. Finally, conclusions and research perspectives on resolving significant bottlenecks or remaining challenges are offered based on recent developments in 2D MoS2-based PDs.
Monitoring the Ecosystem Services Provided by A Woodland Area in North-Eastern Italy for the Population’s Well-Being
Authors: Cremonini Letizia , Georgiadis Teodoro , Ruberto Antonio , Corvaro Francesco , Fazzini Massimiliano
Published: November 2024

In countries such as Italy, there is a notable skewing of the population pyramid toward older age groups and individuals with chronic health conditions. This demographic shift is anticipated to result in increased social costs. It would be advantageous to enhance the physiological conditions and socialization opportunities for the elderly, as this may lead to improved overall well-being and a reduction in healthcare expenditures. It can be reasonably argued that there is a substantial potential for the ecosystem services provided by forest and woodland ecosystems to benefit this particularly vulnerable population. Due to its distinctive territorial configuration, Italy presents a multitude of opportunities for implementing restoration policies. A crucial step is to evaluate the actual welfare benefits that natural areas can offer. To this end, an experimental campaign was conducted in the Parma area of northern Italy, which aimed to assess the positive impact of ecosystem services in comparison to urban environments. The results of this study lend support to the notion that policies which encourage the temporary residency of the elderly in forested and wooded areas may facilitate physiological recovery.
Ecological Indicators and Estimators of Fish and Crustacean Diversity in the Yucatan Peninsula
Authors: Gutiérrez-Aguirre Martha Angélica , Cervantes-Martínez Adrián , Suárez-Morales Eduardo
Published: November 2024

A Species richness is a critical measure in biodiversity studies, providing insights into the diversity and conservation value of ecosystems. This research presents an exhaustive inventory of crustaceans and fish species from the Yucatan Peninsula's epicontinental, underground, and anchialine aquatic systems. Spanning records from 1936 to 2024, the study analyzed over 2,600 entries across 670 aquatic systems, including cenotes, flooded caves lakes, springs, and wetlands. A total of 325 species were recorded, comprising 113 fish and 212 crustacean species. The richness and endemism of these species were assessed through a completeness analysis, utilizing non-parametric models (Chao 2, Jackknife 1, Bootstrap) to estimate potential species richness. Notably, the region exhibits high endemism, especially among crustaceans, with up of 50 species and 2 endemic families unique to the Yucatan Peninsula. The study underscores the importance of the eastern YP for crustaceans and central YP for fish, highlighting areas critical for conservation. These findings emphasize the need for further exploration, as the diversity of aquatic species remains incompletely understood. This comprehensive synthesis aims to inform future conservation strategies, environmental management, and regional planning efforts, particularly highlighting the vulnerability of these unique aquatic systems to environmental degradation.
Everything You Need to Know Before Trying Pulsed Light Treatment for Your Applications
Authors: Filaire Edith , Georgeault Anais , Riedel Christophe , Poinsot Christian
Published: November 2024

Pulsed light (PL) is a non-thermal technology which leads to different applications (food, pharmaceutical and cosmetic packaging, medical devices) by inactivating microorganisms, knowing that the properties of PL technology are cumulative treatment, especially for bacteria. PL uses intense flashes of white light (200 nm–1100 nm wavelengths), rich in UV (200 nm–400 nm) and produced by xenon flash lamps. Localized photothermal and photophysical effects, but also the capability of its UV light component to modify the structure of biomolecules (photochemical effect), such as DNA and proteins, are the main mechanisms involved to explain the inactivation of microorganisms by PL. As compared to other sterilization methods, such as heat or chemical disinfectant treatment, PL treatment has several advantages; it is faster, induces low operational cost and leaves no residues. Nevertheless, no exhaustive data on exposure conditions are available, which would make it possible to repeat, interpret and evaluate the data needed for large-scale industrial deployment of PL in pharmaceutical and cosmetic packaging and medical devices. Research should also focus on understanding the inactivation mechanisms of different bacterial strains, states, and morphologies when exposed to PL.
Case Study of the Application of a Methodology to Adopt Sustainability at SME Industries
Authors: Zapien Guerrero Cristina
Published: November 2024

Companies around the world play an important role in the economic and sustainable development of the regions or areas where they participate. In particular, SME industries are a driver of the economy, social development and environmental care in Mexico, which is why it is necessary to identify how, from the business exercise, it is possible to positively impact its environment without losing its central objective, which is the generation of profitability. In this way, the purpose of this document is to show the development of the implementation of a methodology to adapt sustainability, from the economic, social, environmental and technological point of view, of an electronic components company located in the Northern Border Region of Mexico. Regarding its methodology, it is a five-step proposal: analysis, design, development, evaluation and standardization, being a complex process marked by iterative or cyclical steps. In the case study, special attention was paid to the development of strategy and implementation of indicators. The document highlights the supporting factors and the challenges experienced. While top management support, the presence of a project team and high employee involvement were identified as key supporting factors, the lack of dedicated resources and the lack of time to implement them exert a negative influence on the development process. The results presented here should help other SMEs in developing a sustainability adaptation methodology. In conclusion, the scientific discourse on sustainability adaptation, supporting factors and relevant challenges are added.
Transcriptomic Analysis of HPV-Positive Oesophageal Tissue Reveals Upregulation of Genes Linked to Cell Cycle and DNA Replication
Authors: Shafiq Muhammad Osama , Cakir Muharrem Okan , Bilge Ugur , Pasha Yasmin , Ashrafi G Hossein
Published: November 2024

Human papillomavirus (HPV) is a prevalent sexually transmitted infection, implicated in various cancers, yet its influence in non-cancerous oesophageal tissue remains unclear. This study aims to investigate the gene expression changes associated with high-risk HPV (HR-HPV) in non-cancerous oesophageal tissue to elucidate potential early oncogenic mechanisms. Using RNA sequencing, we compared transcriptomic profiles of HPV-positive and HPV-negative non-cancerous oesophageal tissues. Differential gene expression analysis revealed significant upregulation of cell cycle and DNA replication pathways in HPV-positive samples, specifically involving key genes such as CCNA2, DSN1, and MCM10, which are known to regulate cellular proliferation and genomic stability. Additionally, kinase and transcription factor enrichment analyses highlighted HR-HPV-associated regulatory molecules, including E2F4 and CSNK2A1, suggesting HPV's role in modulating host cell cycle control. These findings support the hypothesis that HPV infection may initiate cellular alterations in oesophageal tissue, potentially predisposing it to malignancy. This study contributes to understanding HPV's impact in non-cancerous tissues and identifies possible biomarkers for early HPV-related cellular changes, offering insights into HPV-driven cancer development beyond traditionally associated sites.
An Estimate of LUCA’s Population in Hadean Oceans
Authors: de Freitas Pacheco José Antonio
Published: November 2024

Recent studies on the physiology of LUCA (Last Universal Common Ancestor) associated to
molecular dating methods suggest that the ancestor cell appeared very early in the history of
the Earth, in a hostile environment, consequence of an intense cosmic bombardment occurred at
that time. In the present investigation, the population size of LUCA was estimated by assuming
that the ancestor cell had a metabolism similar to the methanogen M. jannaschii fed essentially
by H2 and CO2, one of the oldest known metabolism. The cell (wet) mass was evaluated to be
approximately 530 fg and the energy per cell required to drive its metabolism and growth was
estimated to be around 2:7 10?13 W=cell. If LUCA was fed by the chemical energy available
from submarine hydrothermal vents, then its cell population in the Hadean oceans was expected
to be around 1:8 1024. Such a value corresponds to approximately ve orders of magnitude less
than the present estimated number of prokaryote cells in the Earth's oceans. The study of LUCA's
physiology can reveal essential biochemical processes that might be common in extraterrestrial life,
guiding the search for biosignatures on other planets.
Collision Frequency and Energy Transfer Rate in e-He Scattering
Authors: Seitkozhanov Yeldos , Dzhumagulova Karlygash , Shalenov Erik , Jumagulov Murat
Published: November 2024

Using the optical interaction potential between an electron and a helium atom, we calculate the collision frequency and energy transfer rate during the elastic scattering of electrons on helium atoms. The resulting effective frequency as a function of energy exhibits a maximum consistent with experimental data. The rate of energy transfer is in good agreement with other authors' calculations at low electron energies, with discrepancies increasing as the energy increases.
Evaluation of the Timed Up and Go Test in Patients with Knee Osteoarthritis Using Inertial Sensors
Authors: Gianzina Elina , Kalinterakis Georgios , Yiannakopoulos Christos K. , Delis Spilios , Chronopoulos Efstathios
Published: November 2024

There has been a growing interest in the use of inertial sensors to explore the temporal aspects of the Timed-Up-and-Go (TUG) test. The current study aimed to analyze the spatiotemporal parameters and the phases of the TUG test in patients with knee osteoarthritis (KOA) using inertial sensors and to compare the results with those of non-arthritic individuals. The study included 20 patients with KOA and 60 non-arthritic individuals aged 65 to 84 years. All volunteers performed the TUG test and 17 spatiotemporal parameters and phase data were collected wirelessly using the BTS G-Walk inertial sensor. Significant differences were observed between KOA patients and non-arthritic controls, with all but 3 parameters not reaching statistical significance. The results of our study align with findings from similar studies involving diverse patient populations. Our study offers valuable insights into specific characteristics of mobility and functional abilities influenced by KOA, enabling healthcare professionals to develop targeted interventions.
Crystal Structure and Optical Second Harmonic Generation of Self-Assembled Boc-P-Nitro-L-Phenylalanyl-P-Nitro-L-Phenylalanine Dipeptide
Authors: Baptista Rosa M. F. , Ayala Alejandro P. , de Matos Gomes Etelvina , Castro Maria Cidália Rodrigues , Machado Ana V. , Belsley Michael S.
Published: November 2024

Boc(Boc= tert-butoxycarbonyl)-p-nitro-L-phenylalanyl-p-nitro-L-phenylalanine, a dipeptide characterized by acentric symmetry, self-assembles into micro-tapes. This study explores its thermal, structural, and nonlinear optical properties. Thermo-gravimetric analysis reveals an onset degradation temperature of 190 ºC, with primary and secondary peaks at 202 ºC and 220 ºC, respectively. The crystal structure of the dipeptide was determined through single crystal X-ray diffraction at 100 K, confirming its crystallization in space group P2 with two molecules per unit cell. Additionally, optical second harmonic generation polarimetry indicates a significant nonlinear optical response, with an effective coefficient (deff) estimated to be at least 0.52 pm/V. This value is only four times lower than that of state-of-the-art phase-matched β-barium borate nonlinear crystals, highlighting the potential of this dipeptide in nonlinear optical applications.
Thermodynamics of Brain Wave Configurations: Temporal Dynamics of Thought, Sensation, and Motor Acts
Authors: Montgomery Richard Murdoch
Published: November 2024

This study explores the relationship between thermodynamic principles and the temporal dynamics of brain wave configurations, focusing on the processes underlying thought, sensation, and motor acts. By conceptualizing brain activity as a dynamic system that minimizes free energy, we analyze how energy landscapes govern transitions between cognitive states. Brain wave oscillations, including alpha, beta, theta, and gamma rhythms, are modeled as time-dependent attractors that reflect neural efficiency in processing sensory input and generating motor output. Additionally, we explore the thermodynamic time scales of thought (milliseconds to seconds), sensation (milliseconds), and motor acts (tens to hundreds of milliseconds), revealing how neural systems optimize energy dissipation during these processes. This interdisciplinary approach integrates neural dynamics, thermodynamic laws, and cognitive neuroscience to offer insights into the energetic constraints that shape mental and physical actions.