bluuebunny/crossref_metadata_2025 huggingface dataset:
Teacher knowledge: insights for continuing education in Southern Brazil
Authors: Diniz Kurtz Fabiana , Rodrigues da Silva Denilson , Pansera de Araújo Maria Cristina
Published: June 2024

The pandemic caused by Covid-19 has caused education, on a global scale, to face increasing challenges in considerable aspects, from the social and economic inequality of students and teachers to the so-called learning deficit at all levels. Considering the essential dialogue between the university, through its teacher education courses and the basic education school, an applied research project was developed (participatory action research) whose theme presupposes technological innovation from a double perspective, as a means and an end. Means, through the proposed teaching methodology, integrated with technology with a view to changes and innovation in the work processes of basic education teachers when implemented. End, considering the pedagogical products generated after implementing the methodology, digital learning objects that, by nature, encompass different technologies for learning purposes. Furthermore, through the effective participation of teachers linked to the action research proposal, the results suggest the effectiveness of teaching resignification, made possible by continuing education, regarding their role as mediators and curators of the pedagogical process, aware that their knowledge of teacher involves the content, pedagogical and technological dimensions, as well as the role of information and communication technologies as an integral part of their pedagogical work.
Culturas, políticas y prácticas inclusivas según estudiantes universitarios
Authors: Clavijo-Castillo Ruth , Cedillo-Quizhpe Cristina , Cabrera-Ortiz Freddy
Published: June 2024

Diversity in university students is a reality that we cannot ignore, and it has constituted a topic of interest in recent years. This article intends to analyze the progress of inclusive education at university level from the students’ perception according to three dimensions of inclusive education: creation of cultures, generation of policies and development of practices. In order to meet the objective, the Index for inclusion adapted to higher education was applied to 848 university students. Data was processed using descriptive statistics. The results indicate a significant appreciation of dimension A: Creating inclusive cultures (M = 2.00; SD = 0.39) in a very similar extent to dimension C: Development of inclusive practices (M = 1.97; SD = 0.48), while Dimension B: Developing inclusive policies, remains the most underestimated dimension (M = 1.84; DE = 0.43). The results show the response that is required from the university, aiming to generate mechanisms that guarantee access, permanence and completion of higher education, as well as the need to promote policies with an inclusive approach that responds to the diversity of university students.
Исследование устройства зондирования подземных электрокоммуника-ций для тоннелепроходческих комплексов в условиях экранирования кабельной линии железобетонными конструкциями
Authors: Живодерников Андрей Вячеславови , Павленко Александр Валентинович , Хорошев Артём Сергеевич , Щучкин Денис Александрович , Большенко Андрей Викторович
Published: June 2024

Рассмотрены вопросы численного моделирования устройства зондирования подземных электрокоммуникаций на основе магниточувствительных феррозондовых датчиков с различными вариантами взаимного расположения проводников кабельных линий и экранирующего действия железобетонных конструкций для тоннелепроходческих комплексов, работающих в условиях плотной городской застройки. Проведено исследование изменения топологии электромагнитного поля, создаваемого действующей силовой кабельной линией с разными конфигурациями ее проводников путем использования программного комплекса GMSH + GetDP. Установлены параметры ослабления магнитного поля за счет свивки проводников кабеля и размещения кабельной линии в железобетонном кабельном лотке. Получены зависимости для величин магнитной индукции в грунте и ножевой части корпуса проходческого щита от конфигурации проводников кабельной линии и влияния железобетонных конструкций, подтверждена возможность обнаружения электрокоммуникаций на заданном расстоянии опережающего зондирования.
Моделирование динамических процессов в высоковольтных преобразователях частоты в схеме электроприводных газоперекачивающих агрегатов
Authors: Гуляев Игорь Васильевич , Крюков Олег Викторович
Published: June 2024

Рассмотрен частотно-регулируемый электропривод газоперекачивающего агрегата с системой стабилизации напряжения, обеспечивающий устойчивую работу за счет рекуперации кинетической энергии. Работа системы основана на автоматическом изменении частоты модулирующего сигнала преобразователя частоты в соответствии с сигналами рассогласования фактического и требуемого значений напряжения звена постоянного тока. Предложена компьютерная модель на базе программного пакета Matlab Simulink для четырехуровневого инвертора напряжения с переключаемыми конденсаторами, с помощью которой установлены закономерности изменения коэффициентов гармоник напряжения и тока в зависимости от параметров двигателя. Установлены закономерности динамических процессов в системе стабилизации функциональных характеристик преобразователя частоты на основе автоматической коррекции длительности избыточных состояний ключей, влияющих на баланс напряжений, что обеспечивает эффективное управление электроприводных газоперекачивающих агрегатов мощностью 4 МВт.
Мультифизическое моделирование в задачах определения параметров постоянных магнитов электротехнических устройств
Authors: Балабан Анна Леонидовна , Гречихин Валерий Викторович , Юфанова Юлия Викторовна , Некрасов Сергей Александрович
Published: June 2024

Показано, что методологию исследований, основанную на мультифизическом моделировании, как одно из перспективных направлений в изучении физических процессов, анализе и синтезе устройств, целесообразно использовать при разработке электротехнических устройств с постоянными магнитами. Предложена его реализация для определения параметров постоянного магнита в составе беспазового электрического двигателя. Исходной информацией для задачи являются значения магнитной индукции области воздушного зазора, семейства характеристик намагничивания постоянного магнита, соответствующие им температуры постоянного магнита, конструкция, размеры и температура на поверхности двигателя. Последовательно решены обратные задачи теплообмена и магнитостатики с использованием математической модели температурного и магнитного полей двигателя для определения температуры, коэрцитивной силы, напряженности и намагниченности постоянного магнита. Знание этих параметров позволяет установить, подходит ли данный тип постоянного магнита для работы в исследуемом двигателе. Предложенный подход может быть использован при определении и проектировании других электротехнических устройств с постоянными магнитами.
Обоснование преимущества применения обобщенной методики выбора распределительных трансформаторов с учетом взаимосвязи их параметров с величиной и характером нагрузки
Authors: Костинский Сергей Сергеевич
Published: June 2024

Выполнены исследования, связанные с обоснованием преимущества применения обобщенной методики оценки энергоэффективности передачи электроэнергии силовыми трансформаторами I - III габаритов, эксплуатируемыми в распределительных электрических сетях. Для реализации методики расчета коэффициента полезного действия силовых трехфазных двухобмоточных трансформаторов использована схема замещения, обобщающая в один модуль двухобмоточный трансформатор и нагрузку; для силового трансформатора использована Т-образная схема замещения, отличающаяся использованием условно-постоянных коэффициентов и учитывающая взаимосвязь параметров трансформатора с величиной и характером нагрузки. Для оценки относительной погрешности разработанной методики в качестве истинного значения использованы данные, полученные с применением компьютерных моделей систем электроснабжения с трансформаторами соответствующих габаритов, разработанные в программном комплексе Multisim. Расчеты параметров прикладной статистики, необходимые для обоснования преимущества применения разработанной методики, выполнены в программном комплексе STATISTICA 10. Анализ применения формулы для расчета коэффициента полезного действия силовых трансформаторов с использованием условно-постоянных коэффициентов, по сравнению с общепринятым выражением для силовых трансформаторов I – III габаритов, показал, что его использование позволяет повысить точность расчета коэффициентов полезного действия для всего исследуемого ряда номинальных мощностей распределительных трансформаторов, наибольший эффект наблюдается для трансформаторов I габарита. Применение предложенного соотношения для силовых трехфазных двухобмоточных трансформаторов, относящихся к I габариту, позволяет повысить точность расчета в соответствии с медианными значениями в 3,7 раза. При этом снижаются размах вариации в 5,3 раза, децимальный размах и итерквартильный разброс – в 4,5 раза, а среднеквадратичное отклонение – в 4,8 раза.
Educação ambiental e o ensino de micologia no estágio docência em ciências: para uma formação ambiental crítica
Authors: Cintra Pedro Henrique Lima , Obara Ana Tiyomi , Carvalho Andreza de Souza
Published: June 2024

O presente relato de experiência gira em torno da temática do conteúdo da micologia, que foi conteúdo abordado no estágio supervisionado de ciências, dando ênfase em uma visão que foi além de um panorama sistêmico, tendo uma visão mais aplicada no cotidiano dos alunos, assim como para os outros organismos e ecossistemas. A aplicação do conteúdo e como metodologia foi se embasado na metodologia pesquisa-ação crítico-colaborativa, juntamente com a aplicação de diversas estratégias e recursos didáticos. Ao final do processo, os alunos tiveram que realizar sua avaliação em forma de uma história ilustrada, podendo expressar sua criatividade embasada nos conhecimentos aprendidos durante as aulas, mesclando os conhecimentos científicos, assim como a importância dos fungos para os seres humanos e a manutenção do ecossistema.
Malaysian English Language Teachers’ Engagement With Instrumental Support on Facebook
Authors: Rashid Radzuwan Ab , Al-Smadi Omar Ali , Alqaryouti Marwan Harb , Sadeq Ala Eddin
Published: July 2024

This study investigates how Malaysian English language teachers utilize networking sites for social support. It focuses on the social and discursive practices of Malaysian English language teachers as they co-construct social support on Facebook Timelines. The data was collected through semi-structured interviews with 20 Malaysian English language teachers to identify the value of social networking sites for teachers’ development. The findings revealed that the majority of the teachers interviewed had a positive view of the engagement with instrumental support on Timelines even though some teachers questioned the efficacy of Timelines as a platform for the co-construction of instrumental support. The teachers mainly engaged with informational support on Timelines as they perceived the usefulness of Facebook in facilitating the exchange of informational resources. The teachers associate obtaining informational support on Timelines with the ability to communicate important information, communicate immediately, and participate as a lurker, which is useful when teachers want to obtain informational resources without having to engage in conversation with others. This paper argues that teachers' postings on Facebook serve as tools to obtain desirable support, facilitating the improvement of their practices and helping them navigate daily challenges in the workplace.
Punição ou Reputação? Uma análise dos Honorários e Mudança da Auditoria após a Reapresentação das Demonstrações Financeiras
Authors: Brandão Carolini Verdan , Marques Vagner Antônio , Ballarini Laise Mascarenhas , Pain Patrícia
Published: June 2024

Objetivo: Analisar se as empresas que reapresentaram as demonstrações financeiras sofreram alterações nos contratos de auditoria. Verificamos se após a ocorrência do evento, as empresas que reapresentaram as DFs pagaram honorários maiores ou trocaram o auditor/firma de auditoria.
Método: Dados de 323 empresas não financeiras (2.701 observações firma/ano) listadas na Brasil, Bolsa, Balcão (B3), referentes ao período de 2010 a 2020, foram analisados por meio da estatística descritiva, de teste de diferença entre as médias, e da regressão com dados em painel. 
Resultados: Os resultados evidenciaram que empresas que reapresentam suas DFs tendem a pagar honorários maiores e/ou trocar de auditor/firma de auditoria no ano subsequente. Estes sugerem que a reapresentação está associada a uma maior percepção de risco por parte do auditor, porém, as empresas buscam proteger sua reputação trocando de auditor nos casos de reapresentação.
Contribuições: Nossos achados têm potencial de contribuição para investidores, auditores, reguladores, acadêmicos, e membros de conselhos de auditoria e governança, pois apresentam evidências acerca de potenciais implicações empíricas das reapresentações sobre os contratos de auditoria subsequentes, e sugerem que o aumento dos honorários e a mudança da auditoria funcionem como mecanismos de punição ao auditor e/ou proteção do risco de reputação organizacional.
A influência da governança corporativa na estrutura de capital das pequenas e médias empresas
Authors: Ramos Raquel , Florencio Joséte , Fernandes Vasconcelos Adriana
Published: June 2024

Objetivo: Este artigo tem o objetivo de identificar como os mecanismos de governança corporativa adotados pelas pequenas e médias empresas que compõem o Arranjo Produtivo Local (APL) de confecções do Agreste de Pernambuco influenciam na sua estrutura de capital. O trabalho fundamenta-se no arcabouço teórico e nas evidências empíricas relacionadas à Teoria da Agência, bem como sobre governança corporativa e estrutura de capital.
Metodologia: A pesquisa é de caráter quantitativo e os dados primários coletados foram analisados por meio dos testes estatísticos de U Mann-Whitney, Análise Fatorial Exploratória e a técnica de Modelagem de Equações Estruturais por Mínimos Quadrados Parciais.
Resultados: Os resultados revelaram que das 28 assertivas que descreveram as práticas de governança (transparência, prestação de contas e conselho), 16 delas (57,14%) são adotadas pelas empresas pesquisadas. As variáveis significativas no modelo foram a transparência e a prestação de contas, mostrando indícios que esses mecanismos influenciam na estrutura de capital, ou seja, podem facilitar na obtenção de dívida com terceiros (bancário), especialmente de longo prazo. Entratanto, vale salientar que embora essas variáveis tenham se mostrado relevantes como possíveis determinantes na captação de recursos externos, percebe-se que essa adoção ainda está no início, pois o impacto do efeito foi pequeno.
Reliability Assessment of Gored Elbow in Erosive Two-Phase Flow with Sand Particles
Authors: Khan Nauman , Khan Rehan , Wieczorowski Michał , A. Alnaser Ibrahim , Seikh Asiful H , Haji Ya Hamdan
Published: June 2024

Erosion, a major threat to the safety and reliability of piping components, can significantly impact their integrity and functionality. This study employs computational fluid dynamics (CFD) to systematically investigate the erosion behavior of four elbow designs (standard 90-degree elbow, 18-degree gored elbow, 22.5-degree gored elbow, and 30-degree gored elbow) subjected to multiphase air-sand and water-sand flows. Our primary objective is to identify the optimal elbow design that effectively mitigates erosion and enhances the safety and reliability of piping systems. Our findings reveal that the 22.5-degree gored elbow exhibits significantly lower erosion rates compared to other designs, particularly in air-sand flows, making it the superior choice for reducing erosion by up to 32% compared to the standard elbow. However, the standard 90-degree elbow demonstrates greater erosion resistance in water-sand flows. This research contributes valuable insights for selecting the optimal elbow design in multiphase flow, ultimately enhancing the design and longevity of piping systems.
Alter Ego+ A1 ve Yedi İklim Türkçe A1 Kitaplarının Aracılık Etkinlikleri Açısından İncelenmesi
Authors: Sönmez Lebriz
Published: June 2024

Eğitim kurumlarında ve dil merkezlerindeki yabancı dil derslerinde, yapılan sınavlarda, hazırlanan ders kitaplarında öğrenenin hedef dilde karşılıklı iletişim kurabilmesi amaçlanmakta ve ölçülmektedir. Diller İçin Avrupa Ortak Dil Referans Çerçevesi (CEFR), dünya genelinde yabancı dil öğrenenlerin dil becerilerini tanımlayan ve bir standarda kavuşturan uluslararası bir metindir. Dili sosyal ortamlarda kullanılan bir araç, öğreneni de sosyal bir aktör olarak nitelendirmektedir. Yabancı dil derslerinde aracılık eden genelde öğretmendir, ancak CEFR’de, Eylem Odaklı Yaklaşım benimsenerek bunun sadece öğretmen-öğrenci arasında değil, öğrencilerin de birbirlerine aracılık ederek gerçekleşmesi gerektiği belirtilir.
Türkçenin yabancı dil olarak öğretimi ve öğreniminin son yıllarda giderek artması Türkçe öğretim kitaplarının önemini artırmıştır. Yunus Emre Enstitüleri ve TÖMER gibi merkezlerde Yedi İklim Türkçe seti ile ülkemizde ve yurtdışında Fransızca öğretiminde Alter Ego+ seti yaygın bir şekilde kullanılmaktadır. Bu çalışmanın amacı, bu iki kitabın A1 seviyesinde CEFR’de bahsi geçen aracılık etkinlikleri ve stratejilerini hangi uygulamalar aracılığıyla nasıl birleştirdiğini ölçmek ve didaktik yeniliklerin sınıftaki yerini belirlemektir. Araştırma mevcut durumu tespit ederek tablolarla karşılaştırmalı bir bakış açısıyla yapılmıştır. Bu iki kitap karşılaştırıldığında, aracılık etkinliklerinin her iki kitapta farklı şekillerde yer aldığı, yöntem ve içeriklerinin farklı uygulandığı görülmüştür. Sonuçlarının bundan sonra hazırlanacak ders kitaplarında faydalı olması beklenmektedir.
Neuropsychological Assessment and Verification of Cognitive Impairments in Forensic Psychiatry Patients
Authors: Pilechev D.A. , Mikadze Y.V. , Vandysh-Bubko V.V. , Adamovich T.V.
Published: July 2024

In modern clinical psychiatry, there is a tendency to introduce the principle of quasi-dimensional assessment, which can be facilitated by the use of specialized diagnostic methods such as neuropsychological examination. The purpose of the study is to clarify the possibilities of neuropsychological examination during forensic psychiatric examination for persons held criminally responsible. As part of the forensic psychiatric examination of persons brought to criminal responsibility on the basis of the Serbsky State Scientific Center for Social and Forensic Psychiatry Ministry of Health of the Russian Federation, 113 men (age 42±13) were examined with established groups of diagnoses, including organic, personality disorders, as well as schizophrenic spectrum disorders, disorders associated with the use of psychoactive substances. Of these, 50 people were declared “insane” and 63 were “sane”. A neuropsychological examination was performed using qualitative syndrome and quantitative analysis. In individuals with organic mental disorders (OMD), there were more pronounced disorders of neurocognitive functioning compared to those surveyed with other mental disorders. In addition, persons with OMD who were recognized as “insane”, compared with persons recognized as “sane”, had more pronounced disorders in such parameters as: programming, regulation and control, neurodynamic characteristics, auditory—speech memory, with primary interest - frontal (p=0.004), temporal (p=0.004), and subcortical structures (p=0.005). The results of a neuropsychological examination can be used to verify an expert decision at the level of both medical and psychological criteria, primarily in the examination of persons suffering from an organic mental disorder.
Antigenotoxic Properties of Different Plant Oils and the Influence of Olfactory Bias
Authors: Yılmaz Kardas Begumhan
Published: June 2024

In this study, antigenotoxic effects and developmental toxicity of frankincense and blue anemone oils were aimed to be analysed and the olfactory bias was aimed to be checked to see the possibility of an interaction between the olfactory perception and antigenotoxicity of the plant oils. The somatic mutation and recombination test was used to analyze genotoxicity, developmental process of Drosophila melanogaster was screened and the feeding assay was used to perform an olfactory bias test. Genotoxicity test results showed that none of the oils affected the spot frequencies compared to negative control and they caused 73.3 - 100 % inhibitions after the cotreatment with H2O2. None of them caused any significant difference in puparation and eclosion. The frankincense and blue anemone oils were also found antigenotoxic in this study and these effects were independent from the olfactory perception because the rates of feeding were similar to the one observed with negative control.
Northernmost Locality Record of the Near Eastern Fire Salamander, Salamandra infraimmaculata (Martens, 1885) (Amphibia: Salamandridae) in Türkiye
Authors: Özkan Hatice , Bülbül Ufuk
Published: June 2024

We provided a new locality record of Salamandra infraimmaculata, which is distributed in Türkiye, Syria, Lebanon, Iraq, Iran, and Israel. Five juvenile individuals belonging to the species were recorded from Yoncabayırı village located in the İmranlı district of Sivas province, Türkiye. This is the evidence for the northernmost locality of S. infraimmaculata. The new locality record shows that the distribution of the species may extend along the branches of the Kızılırmak River and Tozanlı and Kelkit streams. Future field observations to be performed in the northern districts of Sivas and neighboring provinces to the north may extend the distribution of the species in Türkiye. Morphometric measurements and color-pattern characteristics of the specimens of the species from the new locality were described according to the subspecies distinction. SVL ranged between 63.14 and 78.43 mm in the juveniles of S. infraimmaculata. The color-pattern characteristics of the specimens from the Yoncabayırı population were found similar to the color-pattern features reported in other studies for S. i. orientalis subspecies. The specimens caught in Yoncabayarı had the presence of small yellow spots on the dorsal, which corresponds to the general characteristic of the subspecies
Investigating the Impact of Birt–Hogg–Dubé Syndrome Associated Folliculin (FLCN) and Retinitis Pigmentosa 2 (RP2) Loss on Cilia Function and Morphology
Authors: Kaplan Oktay İsmail
Published: June 2024

Folliculin (FLCN), a GTPase-activating protein (GAP), has been linked to Birt–Hogg–Dubé syndrome, the mTORC1 signaling pathway and cilia. Disruptions in cilia structure and function lead to a group of diseases known as ciliopathies. Birt-Hogg-Dubé syndrome is one of 35 different ciliopathy diseases and there are more than 250 genes that cause ciliopathy diseases. FLCN interacts with kinesin-2 along cilia. The specific role of FLCN in regulating Kinesin-IFT trafficking has, however, remained unclear. In the current study, we investigated the effects of flcn-1 loss (the human ortholog of FLCN) on kinesin and IFT trafficking in C. elegans. The loss of flcn-1 alone did not result in any apparent alterations to kinesin or IFT trafficking within the cilia. However, when we combined the deletion of flcn-1 with the deletion of Retinitis Pigmentosa 2 (RP2), another GAP protein, the ciliary entry of a non-ciliary membrane protein TRAM-1 (Translocation Associated Membrane Protein 1) occured. Additionally, although cilia length was unaltered, our analysis of double mutants revealed the extra branch in wing AWB cilia morphology but not the single rod-like PHA/PHB cilia. In summary, our study reveals the previously unknown functions of FLCN in ciliary gating and cilia morphology in C. elegans
Theoretical Investigations on Phytochemicals: Physical Chemistry, FMO, MEP, Lipophilicity, Water Solubility, Drug-likeness, and Bioavailability
Authors: Karakuş Nihat
Published: June 2024

Naturally-existing chemicals especially phytochemicals have been commonly used for medicinal purposes in terms of both traditional and contemporary respects. Allyl isothiocyanate structure exhibits antimicrobial and anticancer activity, whereas the allitridin, as one of the main components of the garlic, showed antifungal, antitumor, and antioxidant activity. Arabinose and galactose as monosaccharides also play a main role in drug-design research to facilitate drug delivery to target cells and regulate insulin resistance, respectively. Herein, the 3-isothiocyanatoprop-1-ene (Allyl isothiocyanate, AITC), 2,3,4,5-tetrahydroxypentanal (Ar, Arabinose), 1,3-diallyltrisulfane (Allitridin, DATS), 6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol (Galactose, Gal), 6-methyltetrahydro-2H-pyran-2,3,4,5-tetraol (Rhamnose, Rh), and tetrahydro-2H-pyran-2,3,4,5-tetraol (cyclic-Arabinose, C-Ar) agents were investigated by using DFT. The B3LYP/6-311G** level computations were used to optimize the compounds' geometries and then to predict the reactivity indexes of the compounds. Also, lipophilicity and water-solubility features were determined to enlighten the physicochemical characteristics of the compounds. Then, the studied agents' pharmacokinetics were evaluated using the BOILED-Egg and radar graphs. Last, the bioavailability and drug-likeness behaviors were predicted. This trial work will be hoped to provide fundamental electronic and physicochemical insight into the relationship between drug-likeness and electronic structure.
Protective Role of Resveratrol Against Toluene-Induced Oxidative Stress in Rats
Authors: Barat Ahmet , Dere Egemen
Published: June 2024

Toluene is a toxic substance commonly used in the industry that leads to oxidative stress in the body and causes in the formation of reactive oxygen species. In addition to the antioxidants produced by our body, we also obtain antioxidants through foods. Resveratrol is a polyphenol found in many plant species and possesses antioxidant properties. The effects of oxidative stress induced by toluene and the protective effect of resveratrol were investigated through changes in malondialdehyde (MDA) and glutathione (GSH) levels. Male rats were administered different doses of toluene and resveratrol (5 mg/kg, 10 mg/kg, 20 mg/kg), while control groups were given physiological saline and ethanol. At the end of the experiment, blood and lung tissues of the animals were examined, and MDA and GSH levels were measured. According to the obtained data, a significant increase in GSH activity was observed after the administration of toluene. However, in groups treated with combinations of toluene and various doses of resveratrol, a significant decrease in GSH levels was detected. While a significant increase in MDA levels in lung tissues was observed between the control groups and the toluene group, no significant change was observed in blood samples.
Assessment of Serum Beta 2-Microglobulin Levels in Crimean-Congo Hemorrhagic Fever Patients: Implications for Immune Activation and Disease Pathogenesis
Authors: Buyuktuna Seyit Ali , Bolat Serkan , Doğan Kübra , Çakır Yasemin , Dogan Halef Okan
Published: June 2024

Crimean-Congo Hemorrhagic Fever (CCHF) presents a spectrum of clinical manifestations, ranging from asymptomatic cases to severe, life-threatening conditions. Despite extensive research on CCHF pathogenesis, comprehensive understanding remains elusive. Our investigation focused on assessing serum beta 2-microglobulin (β2M) levels in CCHF patients, aiming to elucidate its potential as an immune activation marker and its involvement in disease pathogenesis. The study enrolled 45 CCHF patients and 45 healthy volunteers as a control group. Serum β2M levels were quantified using the immunoturbidimetric analysis method. The patient group was divided into two groups, mild and moderate-severe, using scoring systems. The mean β2M values for the control, mild, and moderate-severe patient groups were 2.27±0.50, 4.37±1.29, and 5.82±2.62 mg/L, respectively (p<0.001). Positive correlations were noted between β2M concentrations and markers such as BUN, creatinine, uric acid, creatine kinase, and aPTT (p<0.001, r=0.684; p<0.001, r=0.602; p=0.003, r=0.439; p=0.008, r=0.392; p=0.019, r=0.348, respectively). Conversely, negative correlations were observed with total protein, albumin, and platelet count (p=0.021, r=-0.342; p=0.003, r=-0.434; p=0.048, r=-0.296, respectively). The findings suggest a prominent inflammatory response in CCHF, indicated by elevated β2M levels, implying its potential role in the molecular mechanisms of the disease
Evaluation of Bioactivity of Ethanol and Water Extracts and Determination of Nutrient Concentrations of Laurel (Laurus nobilis) Plants Grown in İzmir Province
Authors: Daştan Taner , Saraç Handan , Durna Daştan Sevgi , Demirbaş Ahmet
Published: June 2024

This study was conducted to determination of ethanol and water extracts obtained from the leaves of Laurus nobilis (Laurel) plant of the general content by GC-MS analysis, antimicrobial activities of these extracts on some microorganisms, total antioxidant levels (TAS), total oxidant levels (TOS), oxidative stress index (OSI) values, anti-carcinogenic effects on various cell lines and macro and micronutrient concentrations of Laurel (Laurus nobilis) plants cultivated for decorative purposes in parks and gardens of Izmir province of Turkey. TAS, TOS, and OSI values were determined with the aid of Rel Assay Diagnostics kits. In antimicrobial activity analysis, the minimum inhibition concentration (MIC) of the plant extracts against microorganisms was determined by microdilution broth method. Staphylococcus aureus (ATCC 29213), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922), Bacillus cereus (ATCC11778), Candida albicans (ATCC 10231) and Candida tropicalis (DSM11953) microorganisms were used in this analysis. Furthermore, cytotoxic activities of plant extracts were determined by XTT method in normal rat fibroblast cell line, HUVEC, and 2 different human cancer cell lines. At the end of the study, it was found that ethanol and water extracts of the Laurel plants had no antimicrobial activity, low oxidative stress index and good antioxidant activity, and moderate cytotoxic activity on experimented cell lines. Nitrogen (N), Phosphorus (P), Potassium (P), Calcium (Ca), Magnesium (Mg), Iron (Fe), Zinc (Zn), Manganese (Mn) and Copper (Cu) concentrations of plant extracts were respectively identified as 1.68% N, 0.72% P, 1.12% K, 2.40% Ca, 0.45% Mg, 147.4 mg/kg Fe, 13.6 mg/kg Zn, 326.3 mg/kg Mn and 27.8 mg/kg Cu.
Effective Biosorption of Auramin O Dye with Sustainable Chickpea Pods Waste; Isotherms, Kinetics and Thermodynamic Analysis
Authors: Keskin Zehra Saba
Published: June 2024

This study investigated biosorbent properties in removing Auramin O (AO) dye from the aqueous solution of agricultural wastes released from chickpea (Cicer arietinum L.), which is widely produced in Turkey and the world. Biosorption studies were carried out using different values of parameters such as initial AO concentration, dye pH, contact time, temperature, and biosorbent amount. Characterization analyses of the biosorbent used before and after biosorption were carried out by scanning electron microscopy (SEM), energy dispersive X-ray (EDX), Brunauer–Emmett–Teller (BET), Fourier transform infrared spectroscopy (FTIR), and point of zero charge (PZC). Biosorption isotherms were evaluated using Langmuir, Freundlich, and Dubinin-Radushkevich (D-R) isotherm models. As a result of experimental data, it has been shown that the Langmuir isotherm model (R2 = 0.930) is the most compatible model for biosorption, while the biosorption kinetic mechanism proceeds through the pseudo-second-order (PSO) kinetic model (R2 = 0.965) and the intra-particle diffusion model. As a result of thermodynamic studies, it has been reported that biosorption is endothermic (ΔH0>0), spontaneous (ΔS0>0), and entropy-increasing (ΔG0 <0).
Mujer, género y desarrollo rural en los andes de Bolivia
Authors: Chipana-Mendoza Gladys J.
Published: June 2024

En el sector rural, la dimensión de género es importante y emerge como un eje de análisis para interpretar la nueva ruralidad. El género aborda tanto a los varones como a las mujeres, y estos se desenvuelven sobre el actual contexto de cambio climático con variación global del clima de la tierra. Las mujeres y los varones en las zonas rurales de Bolivia tienen muchos roles y oportun idades diferentes en el contexto del desarrollo rural, que no están distribuidos por igual. En este sentido, el objetivo del presente trabajo fue recopilar y analizar información referente a la participación de la mujer en el proceso de desarrollo rural, así como en su perspectiva de género. Se aplicó una metodología que consistió en la recopilación de información secundaria proveniente de artículos científicos, de investigación, de análisis provenientes de revistas científicas indexadas en repositorios internacionales, así como información proveniente de instituciones gubernamentales y no gubernamentales cuyas áreas de acción son inherentes al ámbito agropecuario. De acuerdo con los resultados, a pesar de la incorporación de políticas públicas, normas, leyes, aún se continúa con brechas de género que muestran desigualdad en los Andes de Bolivia, esto principalmente a causa de las costumbres arraigadas que limitan la participación activa de las mujeres rurales.
Colonización endofítica de cepas locales de Trichoderma asperelloides en plantas de quinua, Jujuy-Argentina
Authors: Alvarez Susana Edit , Solis Juan , Yasem de Romero Marta Graciela , Benítez-Ahrendts Marcelo-Rafael
Published: June 2024

El cultivo de quinua es afectado por diversas enfermedades, entre las cuales, el mildiu (Peronospora variabilis Gaum) es la más importante por su prevalencia, severidad e impacto económico. Los hongos endófitos antagonistas representan una opción sustentable para el manejo sanitario de los cultivos. El objetivo del trabajo fue determinar el comportamiento endofítico de cepas locales de Trichoderma asperelloides en plántulas de quinua. Se utilizó la técnica de cultivo para el re-aislamiento del hongo de secciones de raíz, tallo y hoja a los 15 y 30 días después de la aplicación del hongo (dda), y se realizó la observación microscópica de cortes histológicos para caracterizar la colonización del hongo a los 30 dda. El diseño definió los efectos fijos: genotipo de quinua (AMMA-18, RQ-252-18 y RQ-SAC-18), cepa de T. asperelloides: (T1, T15, T16); órgano: raíz, tallo, hoja, y momento de evaluación (15 y 30 dda). La mayor ocurrencia de re-aislamientos fue a los 15 dda en RQ-252-18 desde las tres secciones, seguido por AMMA-2018 y RQ-SAC-18. Se registró diferencias significativas en los niveles de interacción RQ-252-18/T16 siendo superiores los re-aislamientos desde raíz y hoja. A los 30 dda, no se observaron diferencias entre genotipos, y re-asliamientos eran significativamente mayores desde la raíz. El re-aislamiento fue dependiente del tiempo desde la aplicación y la combinación genotipo/cepa. Se observó colonización intercelular de hifas del hongo en el tejido epidérmico y del córtex de tallo y raíz. El trabajo amplía los registros de T. asperelloides como endófito de quinua para futuros estudios de interacción múltiple con P. variabilis u otros factores estrés biótico y/o abiótico.
Produtividade de silagem e grãos de milho em sucessão a plantas de cobertura de inverno
Authors: Guerra Divanilde , Braun Vinicius Leonardo , Redin Marciel , Maisa da Silva Danni , Lorensi de Souza Eduardo , Gehlen Bohrer Robson Evaldo , Enivar Lanzanova Mastrangello
Published: June 2024

O milho é uma cultura de grande importância e com demanda crescente, mas que precisa de grande quantidade de insumos. Por isso, plantas de cobertura antecedendo a cultura estão sendo avaliadas a fim de reduzir a necessidade de uso de adubos químicos. O objetivo do presente estudo foi avaliar o efeito de diferentes combinações e proporções de sementes de plantas de cobertura na produtividade de silagem e grãos de milho. Os tratamentos implantados foram: T1- pousio; T2- Aveia preta-100%; T3- Ervilhaca-100%; T4- 90% ervilhaca + 10% Aveia preta; T5- 75% Ervilhaca + 25% Aveia preta e T6- 50% Ervilhaca + 50% Aveia preta, em delineamento experimental de blocos ao acaso com três repetições. Em todos os tratamentos foram avaliadas a massa verde e seca das plantas de cobertura, além da produtividade de silagem e grãos do milho cultivado na sequência. Como resultados, observou-se que o T2 (100% aveia) apresentou a maior quantidade de massa verde e seca com valores de 31.366 kg ha-1 e 5.420 kg ha-1, respectivamente. Com relação a produtividade de milho silagem, os tratamentos antecessores com ervilhaca (T3-100%) e a combinação de 90% ervilhaca + 10% aveia preta (T4) e de 75% ervilhaca + 25% aveia preta (T5), apresentaram os melhores resultados, com produtividade de 62.775 kg ha-1; 62.451 kg ha-1; e 61.751 kg ha-1, respectivamente. Esses tratamentos também resultaram em maior produtividade de grãos de milho, com valores de 13.860 kg ha-1; 13.720 kg ha-1; e 13.650 kg ha-1, respectivamente. Portanto, a aveia solteira como planta de cobertura apresentou a melhor produção de massa verde e seca, porém não incrementou na produtividade de silagem e de grãos de milho. No entanto, o cultivo da ervilhaca solteira (100%) ou em consórcio (90% e 75%) com aveia preta resultou em maior produtividade de silagem e grãos de milho.
The Role of Emotional Regulation as a Mediator of Self-Compassion and Stress in Students Completing Final Assignments
Authors: Rahmayanti Fitria Dian , Nashori Fuad
Published: July 2024

Final semester students must complete their education on time with a variety of academic assignments. Apart from that, the personal problems they experience are also increasingly complex, making final-semester students vulnerable to depression. This research aims to determine the relationship between self-compassion and stress mediated by emotional regulation in students who complete their final assignments. The design used in this research was quantitative, with three variables. Data were collected using the Self-Compassion Scale with a Cronbach Alpha reliability of 0.872, the Emotion Regulation Questionnaire (ERQ) with a Cronbach Alpha reliability of 0.790, and the stress subscale of the Depression Anxiety Stress Scale (DASS-42) with a Cronbach Alpha reliability of 0.951. The subjects of this research were final-year students who were pursuing higher education in the Special Region of Yogyakarta. Data analysis used a mediation analysis model by testing the relationship between stress (dependent variable) and self-compassion (independent variable) and emotional regulation, cognitive reappraisal facets, and expressive suppression facets (mediator variables) using mediation analysis techniques via JASP. The results showed that the cognitive reappraisal facet of emotional regulation mediated the relationship between self-compassion and stress in students. The emotional regulation facet of expressive suppression did not mediate the relationship between self-compassion and stress in students. In addition, there was a direct negative relationship between self-compassion and stress. Students who complete their final assignment must make efforts to increase self-compassion in order to survive stressful situations.
Strategi Komunikasi Penyuluhan Pencegahan Stunting di BKKBN Kota Baubau
Authors: Chatra Al Shafa Qolby Naviu  , Ansar Suherman  , Wa Nurfida
Published: June 2024

Penelitian bertujuan untuk mengetahui Strategi komunikasi BKKBN Baubau dalam melakukan kegiatan penyuluhan pencegahan stunting dan hambatan yang dialami BKKBN Baubau dalam kegiatan penyuluhan pencegahan stunting. Metode penelitian yang digunakan yaitu deskriptif kualitatif, penelitian dilakukan di BKKBN Kota Baubau,Kecamatan Murhum, Kelurahan Lamangga, Provinsi Sulawesi Tenggara. Penelitian ini dilakukan pada bulan Februari-Maret 2024. Hasil penelitian yang diperoleh menjelaskan bahwa, BKKBN Kota Baubau  menerapkan strategi komunikasi yang komprehensif untuk memberikan penyuluhan pencegahan stunting kepada masyarakat. Yang dimana dalam strateginya dibentuk TPPS (Tim Percepatan Penurunan Stunting) yang dimana semua OPD turut serta dalam bekerjasama di TPPS tersebut. Program TPPS itu sendiri yaitu program Bapak Asuh. Untuk tingkat yang lebih bawah atau tingkat kelurahan, BKKBN Kota Baubau di amanahkan mengelolah TPK (Tim pendamping keluarga ) dengan kegiatan KIE (Komunikasi Informasi dan Edukasi) yang terdiri dari bidang DALDUK (pengendalian penduduk dan penyuluhan), bidang KS (keluarga sejahtera), PKB (Penyuluh keluarga Berencana) dan juga mitra koordinasi yaitu para penyuluh KB serta turut bekerjasama dengan bidan dan juga PKK (Pemberdayaan Kesejahtraan Keluarga. Wartawan yang membantu mempromosikan, media lokal yang digunakan seperti mengirim flyer dan juga baliho di beberapa tempat. BKKBN juga menginovasikan aplikasi elektronik siap nikah dan hamil (Elsimil) dengan tujuan utama untuk menekan angka stunting.
An exploratory study on perception of adolescent girls towards early menarche in a union territory of India
Authors: Periyasamy Saranya , Kittu Devi , Debasish Lopamudra
Published: June 2024

Background: Early menarche is always a challenging one for adolescent girls since it is often associated with inadequate knowledge regarding puberty, adverse reproductive health outcomes and mental health problems. The objective of this study was to explore the perception and attitude of adolescent girls towards early menarche.
Methods: A qualitative study was conducted in the rural field practice area of a Medical College in Puducherry during January to March 2022. The study participants (adolescent girls) were selected by means of purposive sampling. Four Focus Group Discussions were conducted among adolescent girls using an interview guide. The contents were transcribed and codes were derived. The codes were combined to form categories and finally, themes were generated and were interpreted.
Results: Menarche was a shocking experience for the adolescent girls and there was no mental preparedness for accepting it and attaining menarche even earlier, made it still worse. They felt that they lost their childhood identity at a younger age as they looked more matured compared to their peers. They were unable to adjust themselves and it affected their psychosocial state. According to them, factors such as obesity, improper dietary habits, physical inactivity, and also mothers with early age of menarche were the causes of early menarche.
Conclusions: The study participants felt that they had an inadequate knowledge about early menarche and they also found it difficult to cope up with ‘sudden changes into womanhood’. Assuming gender specific roles in their families made them stressed and feels helpless.
Study of the morbidity profile including depression among the elderly in the rural area, East Bangalore
Authors: Menzil Margaret , R. Vinutha , S. K. Kallepalli Swarna , Kamunuri Ravikiran
Published: June 2024

Background: Old age is associated with diminished physiological reserve; so any physical illness, metabolically derangement or pharmacological challenge can worsen cognitive and physical function. The only way to minimize or avoid these will be to be on the lookout and have a proactive approach and assessment in every older patient irrespective of the presenting complaint. This study aimed to assess the socio-demographic profile and self reported morbidity pattern of the elderly population and to estimate the prevalence of depression among the elderly population using the geriatric depression scale.
Methods: A pre-designed, pretested and semi-structured questionnaire was used in the study. The data collection technique is by personal interview of the study subjects.  A pre-designed, pretested and semi-structured questionnaire was used in the study. The data collection technique is by personal interview of the study subjects.
Results: In our study more women were under depression than the men. The most common physical morbidity among the elderly population was cataract (59.7%), followed by arthritis (57.1%), non- specific body pains (40.1%) and hypertension (39%).
Conclusions: Prevalence of depression among the elderly population is reported to be high (84.3%) in this study. Multi morbidity, socio economic factors and financial dependence were factors associated with depression in elderly.
Perceived stress and sleep quality among patients visiting primary and community health centres in Kerala: COVID-19 pandemic context
Authors: Thachorath Abdul Rasik , Kalliyil Fathimathul Jusna , Koorankot Jaseem
Published: June 2024

Background: The quality of sleep, a multifaceted construct encompassing factors such as duration, continuity, and depth, plays a pivotal role in cognitive function, while perceived stress, the subjective appraisal of stressors and one's ability to cope with them, has been identified as a significant factor affecting various aspects of individuals' lives. The present study aimed to investigate “Perceived stress and sleep quality among patients who visited community and primary health centers in Kerala during the COVID-19 pandemic”.
Methods: The sample of the study consist of 60 patients aged between 18 and 50, who visited community and primary health centers in Kerala. Questionnaire for Perceived Stress Scale – Malayalam Version and Sleep Quality Scale were used in this study.
Results: Findings of the study reveals that the patients visiting community and primary health centers in Kerala during the COVID-19 pandemic experience slightly elevated levels of perceived stress, closely aligned with general stress scores. However, their sleep quality remains largely normal, with only minor deviations.
Conclusions: The study reveals a negative impact of pandemic-related stress on sleep timing and quality among these patients. Consequently, it underscores the importance of addressing both stress levels and sleep quality during such public health crises.
Assessment of awareness among parents about dietary habits and its relation to oral health in children: a cross sectional study
Authors: Hugar Shweta S. , Manapragada Saatmika , Hugar Shivayogi , Pattar Vilas , Karvekar Shruti , Sureshbabu Abhirami
Published: June 2024

Background: Dental caries is one of the most common infectious diseases which occurs during early childhood and continues to be major public problem. Establishing healthy dietary habits right from a very young age not only improves the oral health but is essential for a child’s growth and development. Since parents are the main caregivers and prime regulators of child’s dietary intake, they play an important role in shaping child’s oral hygiene habits. Hence it is necessary for them to be aware of the right nutrition, right oral hygiene modalities and frequent dental visits for the betterment of child’s overall health.
Methods: A cross-sectional survey was conducted among parents of children visiting to Department of Paediatric and Preventive Dentistry KAHER’s KLE VK Institute of dental sciences, Belagavi. Subjects were selected according to inclusion criteria. This study was a cross-sectional questionnaire-based study conducted among parents about dietary habits and its relation to oral health in children.
Results: This study shows the statistically significant results with effect among parents about awareness of dietary habits and its relation to oral health in children.
Conclusions: With the results it can be concluded that children who had parents with low knowledge scores were more likely to experience caries and have poor oral hygiene.