bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on Secondary Cable Adjustment for Cable-stayed Bridges Without back Cables
Authors: Sun Zengshou , Liu Xiaocong , Ma Jianfeng
Published: July 2020

The structure of cable-stayed bridge without back cable is a new breakthrough.In this paper, the cable adjustment process of linzhou yingbin bridge is studied. the whole bridge model is established using the finite element software MIDAS CIVIL.This paper compares the measured cable force with the designed cable force and gets range of cable force difference, The influence matrix method is used for the second cable adjustment to ensure that the stress and structural deformation in the process of cable adjustment are within the range of the design requirements.The cable force variation of the whole bridge is detected by dynamic measuring instrument to ensure the construction safety in the process of cable adjustment.

 
Analysis and Countermeasure of Sow’s Postnatal
Authors: Sun Yixiang
Published: July 2020

In the delivery, the sow postpartum non-eating disease is often occurs, once the disease, if not cured, the occurrence of the disease will lead to sows lack of milk or no milk, aff ecting sow and piglets growth and development (for example, Piglets yellow and white diarrhea), more serious and even death, can also lead to sow death or forced to eliminate, aff ecting the normal production and reproduction of the continued, to the pig industry to bring some economic losses. In this paper, the sow postnatal do not eat the careful observation, do the corresponding experiments and records, the system introduced the sow postpartum not eat the performance and impact, and fi nally according to the sow postnatal do not eat the diff erent factors, to take the appropriate countermeasures and Prevention. Through comparison, a more comprehensive comprehensive prevention and control program is obtained.
Evaluations of Bole Injections for Protecting Engelmann Spruce from Mortality Attributed to Spruce Beetle (Coleoptera: Curculionidae) in the Intermountain West
Authors: Fettig Christopher J. , Munson A. Steven , Grosman Donald M. , Blackford Darren C.
Published: July 2020

Bark beetles are important disturbance agents in coniferous forests, and spruce beetle, Dendroctonus rufipennis (Kirby) (Coleoptera: Curculionidae), is one of the more notable species causing landscape-level tree mortality in western North America. We evaluated the efficacy of bole injections of emamectin benzoate (TREE-äge®; Arborjet Inc., Woburn, MA) alone and combined with propiconazole (Alamo®; Syngenta Crop Protection Inc., Wilmington, DE) for protecting Engelmann spruce, Picea engelmannii Parry ex Engelmann (Pinales: Pinaceae), from mortality attributed to colonization by D. rufipennis. Two injection periods in 2013 (the spring and fall of the year prior to trees first being challenged by D. rufipennis in 2014) and distributions of injection points (7.6- and 15.2-cm spacings) were evaluated. Tree mortality was monitored over a 3-yr period (2014–2017). Emamectin benzoate injected in spring at a narrow spacing (7.6 cm) was the only effective treatment. Two (but not three) field seasons of protection can be expected with a single injection of this treatment. We discuss the implications of these and other results regarding the use of emamectin benzoate and propiconazole for protecting western conifers from mortality attributed to bark beetles, and provide suggestions for future research. A table summarizing the appropriate timing of treatments in different bark beetle/host systems is provided.
A Survey of Automated Financial Statement Fraud Detection with Relevance to the South African Context
Authors: Mongwe Wilson , Malan Katherine
Published: July 2020

Financial statement fraud has been on the increase in the past two decades and includes prominent scandals such as Enron, WorldCom and more recently in South Africa, Steinhoff. These scandals have led to billions of dollars being lost in the form of market capitalisation from different stock exchanges across the world. During this time, there has been an increase in the literature on applying automated methods to detecting financial statement fraud using publicly available data. This paper provides a survey of the literature on automated financial statement fraud detection and identifies current gaps in the literature. The paper highlights a number of important considerations in the implementation of financial statement fraud detection decision support systems, including 1) the definition of fraud, 2) features used for detecting fraud, 3) region of the case study, dataset size and imbalance, 4) algorithms used for detection, 5) approach to feature selection / feature engineering, 6) treatment of missing data, and 7) performance measure used. The current study discusses how these and other implementation factors could be approached within the South African context.
Effect of Glycemic Control on Right Heart Functions in Type 2 Diabetes Mellitus Patients Free of Clinical Cardiovascular Disease
Authors: Ziyrek Murat
Published: July 2020

Diabetes mellitus (DM) is one of the most common endocrine disorders. 90% percent of all diabetics are diagnosed with type 2 DM. DM is closely associated with various vascular diseases, and successful glycemic control prevents micro and macrovascular complications. Although there is data about the relation between glycemic control and left ventricle function, there is hardly any data about the relation between the right ventricular function. We analyzed the relationship between glycemic control and right ventricle function in type 2 DM patients free of clinical cardiovascular diseases (CVD). Patients were selected from the cardiology outpatient clinic. 53 patients formed the DM group; 51 patients formed the control group. All patients' demographic data were recorded. Biochemical tests and echocardiographic examinations were performed. RA and RV diameters were significantly higher in DM group (3.36±0.32 vs 3.13±0.34, P=0.015; 2.80±0.32 vs 2.56±0.22 P=0.005 respectively). Myocardial velocity during isovolumetric contraction (RV/IVV) and myocardial acceleration during Isovolumetric contraction (RV/IVA) were significantly lower in the DM group (14.4±3.17 vs 16.04±4.13 P=0,019; 3.25±0.75 vs 3.95±1,25 P=0.015). There was an intermediate negative correlation between RV/IVV and HBA1C (r=-0.406; P=0.036). HBA1C level was an independent risk factor for RV IVV (β=-0.406; P=0.036). It is shown that RA, RV diameter were significantly higher; RV/IVV and RV/IVA were significantly lower in diabetes mellitus patients free of CVD. Furthermore, there was a significant negative correlation between RV/IVV and HBA1C levels. HBA1C level was an independent risk factor for RV/IVV.
The Effect of Preoperative Administration of Duloxetine on Postoperative Pain After Laparoscopic Myomectomy
Authors: Hatami Maryam , Kheirati Arezoo , Behdad Shekoufeh , Javaheri Atiye , Vaziribozorg Sedighe
Published: July 2020

The purpose of this study was to evaluate the effect of preoperative administration of duloxetine on postoperative pain after laparoscopic myomectomy. In this double-blind clinical trial study, 57 patients aged 18-55 years with ASA I or II undergoing laparoscopic myomectomy involved. The case group received oral duloxetine 60 mg, and the control group received placebo 2 hours before the surgery. Pain scores, total analgesic consumption during 24 hours, recovery discharging time, nausea, vomiting, dizziness, and hemodynamic changes were recorded and compared between two groups. The pain severity was significantly lower in the case group at 2, 12, and 24 hours after the operation (P<0.05). There were no significant differences in dizziness, nausea, vomiting, systolic and diastolic blood pressure, and heart rate of patients between two groups before the surgery, 5 and 30 minutes after the induction, and after the recovery. Duloxetine administration prior to laparoscopic surgery myomectomy can reduce postoperative pain without inducing side effects in patients.
Effects of Backward Gait Training on Ground Reaction Forces in Patients with Medial Knee Osteoarthritis
Authors: Jalalvand Ali , Anbarian Mehrdad
Published: July 2020

Introduction: The aim of this study was to investigate the effects of backward gait training protocol on ground reaction forces in Patients with medial knee Osteoarthritis.
Methods: This quasi-experimental study was performed with a pretest-posttest design in two groups of healthy and unhealthy and the experimental group (participants with medial knee osteoarthritis). The participants were 21 healthy and 42 unhealthy men with knee osteoarthritis who were divided into two experimental and control groups according to the Kellgren and Lawrence radiologic scale and the visual analogue scale. The experimental group performed backward gait training for six weeks. Two Kistler force plates (1000Hz) were used to measure parameters by Vicon Nexus 1.8.5, Polygon 4.1.2 software. For statistical analysis One-Way ANOVA test was used through SPSS, version 20 (p≤0.05).
Results: Before training, there was a significant difference between the groups of the patients and healthy participants for the first peak of vertical (Fz1) and vertical valley (valley), braking force (AP1), propulsive force (AP2) of ground reaction forces (P<0.05). The training protocol had a significant effect on increasing propulsive force (PPre=0.021, Ppost=0.068) and braking force (PPre=0.022, Ppost=0.077) in the experimental group compared to the healthy group; and there was no significant difference between the groups after training compared to pre-exercise (baseline). Exercise did not affect on the components of vertical force.
Conclusion: Loss of braking-pushing forces and first peak of vertical ground reaction force (Fz1) could reflect limb pain or poor performance. Backward gait training protocol had a significant effect on braking-pushing forces.
Primary health care policy and vision for community pharmacy and pharmacists in Indonesia
Authors: Hermansyah Andi , Wulandari Luh , Kristina Susi A. , Meilianti Sherly
Published: July 2020

The practice of community pharmacy in low and middle-income countries, including in Indonesia, is often described as in the state of infancy with several intractable barriers that have been substantially and continuously hampering the practice. Such description might be valid in highlighting how pharmacy is practiced and the conditions within and beyond community pharmacy organizations. Therefore, it is not surprising that the concept of integrating community pharmacy into the primary care system may not be considered in the contemporary discourse despite the fact that community pharmacy has been operating within communities for years. However, in the case of Indonesia, we argue that changes in the health care system within the past decade particularly with the introduction of the universal health coverage (UHC) in 2014, may have significantly amplified the role of pharmacists. There is good evidence which highlights the contribution of pharmacist as a substantial health care element in primary care practice. The initiative for employing pharmacist, identified in this article as primary care pharmacist, in the setting of community health center [puskesmas] and the introduction of affiliated or contracted community pharmacy under the UHC have enabled pharmacist to work together with other primary care providers. Moreover, government agenda under the “Smart Use of Medicines” program [Gema Cermat] recognizes pharmacists as the agent of change for improving the rational use of medicines in the community. Community pharmacy is developing, albeit slowly, and is able to grasp a novel position to deliver pharmacy-related primary care services to the general public through new services, for example drug monitoring and home care. Nevertheless, integrating community pharmacy into primary care is relatively a new notion in the Indonesian setting, and is a challenging process given the presence of barriers in the macro, meso- and micro-level of practice.
EFEKTIVITAS METODE DISKUSI DALAM MENINGKATKAN HASIL BELAJAR PKN MATERI MENJELASKAN PROSES PEMILU DAN PILKADA PADA SISWA KELAS VI SDN 7 MONTONG BAAN
Authors: Sahnun S
Published: July 2020

Metode diskusi adalah metode pembelajaran berbentuk tukarmenukar informasi, pendapat dan unsur-unsur pengalaman secara teraturdengan maksud untuk mendapat pengertian yang sama. Prinsip ini perluditanamkan pada siswa sebagai sarana belajar mengungkapkan gagasan.Penelitian ini bertujuan untuk mengetahui efektivitas penggunaan metodediskusi dalam meningkatkan hasil belajar PKn materi Menjelaskan prosesPemilu dan Pilkada pada siswa kelas VI SDN 7 Montong Baan. Jenispenelitian ini adalah penelitian tindakan kelas. Subjek penelitian siswa kelasVI SDN 7 Montong Baan. Metode yang digunakan dalam penelitian iniadalah observasi, angket/tes, dan wawancara. Observasi digunakan untukmengamati jalannya proses tindakan yang dilakukan. Angket/tes digunakanuntuk mengetahui hasil belajar yang dicapai. Sedangkan wawancaradigunakan untuk mendapatkan informasi tentang penerapan metode diskusidalam proses pembelajaran.Hasil penelitian tindakan ini adalah menunjukkan bahwa hasil belajar PKnmateri Menjelaskan proses Pemilu dan Pilkada pada siswa kelas VI SDN 7Montong Baan sebelum dilakukan tindakan sangat rendah. Hal ini dibuktikandengan persentasi keberhasilannya adalah 42,86%. Setelah dilakukantindakan penggunaan metode diskusi hasil belajar tergolong sangat baik. Halini terbukti dengan persentasi keberhasilan pada variabel hasil belajar siswapada siklus 1 yaitu 71,43% dengan kriteria baik dan siklus 2 adalah 91,43%dengan kriteria sangat baik.
Evaluasi Manajemen Jurusan dalam Meningkatkan Kemampuan Menulis Skripsi Berbahasa Arab Mahasiswa Jurusan PBA FTK UIN Mataram
Authors: Nurman Muhammad
Published: July 2020

This article aims to explain: (1) the factors that caused students ofthe PBA FTK UIN Mataram departemen difficulties in writing Arabic theses,(2) management of majors in improving the ability to write Arabic-languagethesis students of PBA FTK UIN Mataram departemen. The approach usedin this study was a qualitative approach with a case study design. The datasources in this study were students majoring in PBA departemen, PBA alumni,and permanent lecturers majoring in PBA. Data collection techniques usedwere interviews, documentation studies and observations while data analysiswas carried out using descriptive-qualitative analysis techniques. The resultsof this study are: (1) The causes of students majoring in PBA FTK UINMataram departemen difficulties in writing Arabic theses are (a) input,many PBA students come from high school or public school with minimalbasic language. (b) the willingness to speak Arabic in students is still low. (c)department policies are still not firm, namely still giving students the freedomto write Indonesian theses. (d) department facilities and infrastructureare still minimal, namely Arabic books or references are still lacking. (2)Management of majors in improving the ability to write Arabic theses forstudents majoring in PBA FTK UIN mataram namely (a) Growing interestand providing awareness to students. (b) Making policies requires studentsto write Arabic language theses and strive for students to communicate inArabic, at least when in PBA. (c) Making teaching materials for all subjects inPBA majors. (d) Implementing the IQF curriculum. (e) Carry out produckbasedpracticum activities. (f ) Making guidelines for Arabic thesis writing
Visitando a Mary Shelley. Diálogos didácticos entre ciencia y literatura.
Visiting Mary Shelley. Educational dialogues between science and literature
Authors: Martín Ezpeleta Antonio , Echegoyen Sanz Yolanda
Published: July 2020

Enmarcado en un proyecto de innovación docente relacionado con la integración de las ciencias y las letras destinado a alumnos de los Grados de Maestro en Educación Primaria e Infantil, este trabajo presenta una experiencia educativa basada en la novela mítica Frankenstein, de la creadorainglesa Mary Shelley (1818). La elección de la obra viene motivada por la efeméride de su publicación, pero especialmente por la fortuna de poder asistir a la exposición “Frankenstein o el moderno Prometeo. Diálogos entre ciencia y literatura”, comisariada por Pedro Ruiz-Castell en la Universitat de València. Esta motivó una secuencia didáctica llevada a cabo por más deun centenar de maestros en formación que tenía por objetivo principal el desarrollo de estrategias de mediación cultural a partir del diseño de materiales didácticos para niños, con la peculiaridad de que estos integraban aspectos relacionados con las ciencias y la literatura.

This work presents an educationalexperience based on the novel Frankensteinby Mary Shelley (1818) with alumni of the degrees in early childhood educationand primary education, as part of an educational innovation project related to the integration of sciences and arts. The novel was selected because of the ephemeris of its publication, but also because there was an exposition entitled “Frankenstein or the modern Prometheus. Dialogues between science and literature”, directed by Pedro Ruiz-Castell atthe University of Valencia. This lead to a learning unit carried out by more than one hundred pre-service teachers with the main goal of developing cultural mediation strategies based on the design of learning materials for children integrating science and literature.
La práctica reflexiva en el Practicum de Historia del Máster de Formación del Profesorado. Reflective practice in the Practicum of History of the Master's Degree in Teacher Training.
Authors: Andreu Mediero Beatriz
Published: July 2020

En el marco del sistema de competencias europeo, este trabajo analiza la importancia de la práctica reflexiva para la enseñanza-aprendizaje de la Historiaen el Prácticum del Máster de Formación del Profesorado, en su especialidad de Geografía e Historia, con el fin de lograr un profesorado intelectualmente comprometido, reflexivo y crítico.Para ello, a través de la investigación cualitativa y la investigación-acción, se pretende: conocer cómo se desarrolla la práctica reflexiva en el modelo de Practicum portugués, concretamente en el Practicum de Historia de la Universidad de Porto, Portugal; analizar el modelo de Practicum de la especialidad de Geografía e Historia de la Universidad de Las Palmas de Gran Canaria, acercándonos a la valoración que el alumnado hace de las prácticas y de la relación entre teoría y práctica, y, por último, reflexionar sobre nuestra propia experiencia docente durante las prácticas del Máster.

Within the framework of the European competency system, this work: analyzes the importance of reflective practice for the teaching-learning of Social Sciences, specifically of History, in the Practicumof the Master's Degree in Teacher Training, in its specialty of Geography and History, in order to achieve an intellectually committed, reflective and critical faculty.For this purpose, through qualitative research and action research, we intend to know how reflective practice is developed in the Portuguese Practicummodel, specifically in the History Practicumof the University of Porto, Portugal; analyze the Practicummodel of the Geography and History specialty of the University of Las Palmas de Gran Canaria, approaching students' assessment of practices and the relationship between theory and practice, and finally, reflecting on our own teaching experience during the practices of the Master.
Linear and Nonlinear Dynamic Methods towards Investigating Proprioception Impairment in Non-specific Low Back Pain Patients
Authors: Shokouhyan Seyed Mohammadreza , Davoudi Mehrdad , Hoviattalab Maryam , Abedi Mohsen , Bervis Soha , Parnianpour Mohamad , Brumagne Simon , Khalaf Kinda
Published: July 2020

Central nervous system (CNS) uses vision, vestibular, and somatosensory information to maintain body stability. Research has shown that there is more lumbar proprioception error among low back pain (LBP) individuals as compared to healthy people. In this study, two groups of 20 healthy people and 20 non-specific low back pain participants (LBP) took part in this investigation. This investigation focused on somatosensory sensors and in order to alter proprioception, a vibrator (frequency of 70Hz, amplitude of 0.5 mm) was placed on the soleus muscle area of each leg and two vibrators were placed bilaterally across the lower back muscles. Individuals, whose vision was occluded, were placed on two surfaces (foam and rigid) on force plate, and trunk angles were recorded simultaneously. Tests were performed in 8 separate trials; the independent variables were vibration (4 levels) and surface (2 levels) for within subjects and 2 groups (healthy and LBP) for between subjects (4×2×2). MANOVA and multi-factor ANOVA tests were done. Linear parameters for center of pressure (COP) (deviation of amplitude, deviation of velocity, phase plane portrait (PPP), and overall mean velocity) and nonlinear parameters for COP and trunk angle ((recurrence quantification analysis) RQA and Lyapunov exponents) were chosen as dependent variables. Results indicated that NSLBP individuals relied more on ankle proprioception for postural stability. Similarly, RQA parameters for the COP on both sides and for the trunk sagittal angle indicated more repeated patterns of movement among the LBP cohort. Analysis of short and long Lyapunov exponents showed that people with LBP caused no use of all joints in their bodies (non-flexible), are less stable than healthy subjects.
Impact of Dietary Habit, Iodine Supplementation and Smoking Habit on Urinary Iodine Concentration During Pregnancy in A Catalonia Population
Authors: Torres M Teresa , Vila Lluis , Manresa Josep Maria , Casamitjana Roser , Prieto Gema , Toran Pere , Falguera Gemma , Frances Lidia
Published: July 2020

Background: The nutritional status of women during pregnancy can have a considerable effect on maternal and fetal health, and on perinatal outcome. The aim was to assess the changes occurring in dietary iodine intake, KI supplementation, and smoking habit, and the impact of these changes on the urinary iodine concentration (UIC) during pregnancy in a population of women in Catalonia (Spain). Methods: Between 2009-2011 an observational study including a cohort of women whose pregnancy was monitored in the publically-funded health system in a central region of Catalonia. Women received individual educational counseling imparted, a dietary questionnaire was completed, and a urine sample collected for iodine determination at each trimester visit. Results: 633 (67.9%) women answered the questionnaire at all 3 visits. The percentage of women with a desirable UIC (≥150μg/L) increased from the first to the second trimester and remained stable in the third (p<0.001). Analysis of the relationship between UIC≥150 μg/L and the women’s dietary habits showed that the percentage with UIC≥150 μg/L increased with greater consumption of milk, fresh vegetables, and fruit in the first trimester, and the same was true for iodized salt use in all three trimesters and iodine supplementation in all three. Conclusion: During pregnancy increased intake of milk, iodized salt, and iodine supplements was associated with an increase in the UIC.
Putting the Squeeze on Molecule-Based Magnets: Exploiting Pressure to Develop Magneto-Structural Correlations in Paramagnetic Coordination Compounds
Authors: Brechin Euan , Etcheverry-Berrios Alvaro , Parsons Simon , Kamenev Konstantin , Probert Michael , Moggach Stephen , Murrie Mark
Published: July 2020

The cornerstone of molecular magnetism is a detailed understanding of the relationship between structure and magnetic behaviour, i.e. the development of magneto-structural correlations. Traditionally, the synthetic chemist approaches this challenge by making multiple compounds that share a similar magnetic core but differ in peripheral ligation. Changes in the ligand framework induce changes in the bond angles and distances around the metal ions which are manifested in changes to magnetic susceptibility and magnetisation data. This approach requires the synthesis of series of different ligands and assumes that the chemical/electronic nature of the ligands and their coordination to the metal, the nature and number of counter ions and how they are positioned in the crystal lattice, and the molecular and crystallographic symmetry have no effect on the measured magnetic properties. In short, the assumption is that everything outwith the magnetic core is innocent, which is a huge oversimplification. The ideal scenario would be to have the same complex available in multiple structural conformations, and this is something that can be achieved through the application of external hydrostatic pressure, correlating structural changes observed through high pressure single crystal X-ray crystallography with changes observed in high pressure magnetometry, in tandem with high pressure inelastic neutron scattering (INS), high pressure electron paramagnetic resonance (EPR) spectroscopy and high pressure absorption/emission/Raman spectroscopy. In this review, which summarises our work in this area over the last 15 years, we show that the application of pressure to molecule-based magnets can (reversibly): (1) lead to changes in bond angles, distances and Jahn-Teller orientations; (2) break and form bonds; (3) induce polymerisation/depolymerisation; (4) enforce multiple phase transitions; (5) instigate piezochromism; (6) change the magnitude and sign of pairwise exchange interactions and magnetic anisotropy and (7) lead to significant increases in magnetic ordering temperatures.
Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction
Authors: Mayr Fabian , Möller Gabriele , Garscha Ulrike , Fischer Jana , Rodríguez Castano Patricia , Inderbinen Silvia G. , Temml Veronika , Waltenberger Birgit , Schwaiger Stefan , Hartmann Rolf W , Gege Christian , Martens Stefan , Odermatt Alex , Pandey Amit V , Werz Oliver , Adamski Jerzy , Stuppner Hermann , Schuster Daniela
Published: July 2020

Natural products comprise a rich reservoir for innovative drug leads and are a constant source of bioactive compounds. To find pharmacological targets for new or already known natural products using modern computer-aided methods is a current endeavor in drug discovery. Nature’s treasures, however, could be used more effectively. Yet, reliable pipelines for large scale target prediction of natural products are still rare. We have developed an in silico workflow consisting of four independent, stand-alone target prediction tools and evaluated its performance on dihydrochalcones (DHCs) – a well-known class of natural products. Thereby, we revealed four previously unreported protein targets for DHCs, namely 5-lipoxygenase, cyclooxygenase-1, 17β- hydroxysteroid dehydrogenase 3, and aldo-keto reductase 1C3. Moreover, we provide a thorough strategy on how to perform computational target prediction and guidance on using the respective tools.
Displacement Detection Decoupling in Counterpropagating Dual-beams Optical Tweezers with Large-sized Particle
Authors: Zhu Xunmin , Li Nan , Yang Jianyu , Chen Xingfan , Hu Huizhu
Published: July 2020

Optical tweezers, as a kind of ultra-sensitive acceleration sensing platform, show a minimum measurable value inversely proportional to the square of the diameter of the levitated spherical particle. However, the coupling of the displacement measurement between axes becomes notable, along with the increasing of the diameter. This paper analyzes the source of coupling in a forward scattering far-field detection regime and proposes a novel method of suppression. We theoretically and experimentally demonstrated that when three variable irises added into detection optics, without changing other parts of optical structures, the decoupling of triaxial displacement signals mixed with each other show significant improvement. The detection coupling ratio reduction of 49.1 dB and 22.9dB has been realized in radial and axial direction respectively, which is principally in accord with simulations. This low cost and robust approach makes it possible to accurately measure three-dimensional mechanical quantities simultaneously and even go further such as active cooling the particle to quantum ground state.
The Effect of Specific Locomotor Experiences on Infants’ Avoidance Behaviour on Real and Water Cliffs
Authors: Burnay Carolina , Cordovil Rita , Button Chris , Croft James L. , Schofield Matthew , Pereira Joana , Anderson David I.
Published: July 2020

Infants’ avoidance of drop-offs has been described as an affordance learning that is not transferable between different locomotor postures. In addition, there is evidence that infants perceive and act similarly around real and water cliffs. This cross-sectional study investigated the effects of specific locomotor experiences on infants’ avoidance behaviour using the Real Cliff / Water Cliff paradigm. The experiments included 102 infants, 58 crawling, but pre-walking, infants (Mage= 11.57 months, SD = 1.65) with crawling experience ranging between 0.03 and 7.4 months (M = 2.16, SD = 1.71) and 44 walking infants (Mage = 14.82 months, SD = 1.99), with walking experience ranging between 0.13 and 5.2 months (M = 1.86, SD = 1.28). The association between crawling experience and crawlers’ avoidance of the real and water cliffs was confirmed. Importantly, crawling and total self-produced locomotor experience, and not walking experience, were associated with walkers’ avoidance behaviour on both cliffs. These results suggest that some degree of perceptual learning acquired through crawling experience was developmentally transferred to the walking posture. A longer duration of crawling experience facilitates a more rapid recalibration to the new walking capability. In addition, there was no difference in infants’ avoidance of falling on the real and the water cliff. However, infants explored the water cliff more than the real cliff, revealing more enticement to examine bodies of water than for drop-offs.
Thermal Bridge Modeling and a Dynamic Analysis Method Using the Analogy of a Steady-State Thermal Bridge Analysis and System Identification Process for Building Energy Simulation: Methodology and Validation
Authors: Kim Heegang , Yeo Myoungsouk
Published: July 2020

It is challenging to apply heat flow through a thermal bridge, which requires the analysis of 2D or 3D heat transfer to building energy simulation(BES). Research on the dynamic analysis of thermal bridges has been underway for many years, but their utilization remains low in BESs. This paper proposes a thermal bridge modeling and a dynamic analysis method that can be easily applied to BESs. The main idea begins with an analogy of the steady-state analysis of thermal bridges. As with steady-state analysis, the proposed method first divides the thermal bridge into a clear wall, where the heat flow is uniform, and the sections that are not the clear wall (the thermal bridge part). For the clear wall part, the method used in existing BESs is applied and analyzed. The thermal bridge part (TB part) is modeled with the linear time-invariant system (LTI system) and the system identification process is performed to find the transfer function. Then, the heat flow is obtained via a linear combination of the two parts. This method is validated by comparing the step, sinusoidal and annual outdoor temperature response of the finite differential method(FDM) simulation. When the thermal bridge was modeled as a third-order model, the root mean square error(RMSE) of annual heat flow with the FDM solution of heat flow through the entire wall was about 0.1W.
Blockchain-enable Contact Tracing for Preserving User Privacy During COVID-19 Outbreak
Authors: Arifeen Md. Murshedul , Al Mamun Abdullah , Kaiser M Shamim , Mahmud Mufti
Published: July 2020

Contact tracing has become an indispensable tool of various extensive measures to control the spread of COVID-19 pandemic due to novel coronavirus. This essential tool helps to identify, isolate and quarantine the contacted persons of a COVID-19 patient. However, the existing contact tracing applications developed by various countries, health organizations to trace down the contacts after identifying a COVID-19 patient suffers from several security and privacy concerns. In this work, we have identified those security and privacy issues of several leading contact tracing applications and proposed a blockchain-based framework to overcome the major security and privacy challenges imposed by the applications. We have discussed the security and privacy measures that are achieved by the proposed framework to show the effectiveness against the security and privacy issues raised by the existing mobile contact tracing applications.
Detection of the CD18 gene mutation as a marker of BLAD genetic disorder of Holstein-Friesian cattle in West Java
Authors: Nasrulloh Mukh Fajar , Wulandari Ari Sulistyo , Indriawati Indriawati , Margawati Endang Tri , Volkandari Slamet Diah
Published: July 2020

Objective: Bovine Leukocyte Adhesion Deficiency (BLAD) is a genetic disorder in Holstein-Friesian (HF) cattle that have a significant economic impact on dairy cattle breeding. Mutation c.383A>G in Cluster of Differentiation Molecule 18 (CD18) gene was known as related to BLAD. This study aimed to detect the CD18 gene mutation that causes BLAD of HF cattle in the West Java Province.

Methods: The genomic DNA was extracted from 88 blood samples of HF cattle from Cibungbulang-Bogor (n=34), Ciampea-Bogor (n=31), and Sukabumi (n=23) by the GB300 DNA extraction kit, GeneaidTM. The CD18 gene mutation was detected by PCR-RFLP analysis using the TaqI restriction endonuclease.

Results: All samples in this study produced two fragments DNA, i.e., 359 bp and 260 bp with the monomorphic homozygote genotype (BB). HF cattle with BB genotype indicated as normal cattle and did not carry BLAD.
Conclusions: All samples in the three populations of West Java were free of BLAD genetic disorder. Identification of BLAD on HF cattle in other places, including bulls in the Center of Semen Production in Indonesia was needed to prevent this genetic disorder.
SYSTEMATIC REVIEW: SENAM HAMIL UNTUK MASA KEHAMILAN DAN PERSIAPAN PERSALINAN
Authors: Hidayati Ulfah
Published: July 2020

Latar Belakang: Ketidaknyamanan ibu hamil akan meningkat dengan bertambahnya usia kehamilan. Ibu hamil membutuhkan persiapan fisik dan psikologis untuk persalinan. Tujuan penulisan artikel ini untuk mengetahui senam hamil selama kehamilan memberikan manfaat selama kehamilan dan persiapan melahirkan

Metode: Sistematik review menggunakan database : Scopus, Pubmed, Sciene Direct, dan Emerald. Hasil pencarian yang memenuhi kreiteria adalah 8 kemudian dilakukan analisis artikel.

Hasil: Olahraga kehamilan dapat menurunkan ketidaknyamanan selama kehamilan dan mempersiapkan fisik dan psikologis kehamilan untuk melahirkan. Olahraga selama kehamilan dapat dapat dilakukan dengan senam hamil, yoga kehamilan, dan olahraga lainnya.

Kesimpulan: Senam hamil dapat menurunkan ketidaknyamanan selama kehamilan dan mempersiapkan fisik dan psikologis ibu untuk melahirkan.
HUBUNGAN BERAT BADAN DAN TEKANAN DARAH PADA LANSIA
Authors: Nugraheni Angesti , Mulyani Sri , Cahyanto Erindra Budi , Musfiroh Mujahidatul , Sukamto Ika Sumiyarsi
Published: July 2020

Latar Belakang: Aktivitas fisik yang dilakukan pada lansia cenderung berkurang, hal ini mengurangi pengeluaran energi untuk metabolisme lemak sehingga menyebabkan kelebihan berat badan dan berakibat otot jantung bekerja lebih keras. Aliran melalui pembuluh darah yang berkurang elastisitasnya menyebabkan jantung bekerja lebih keras sehingga tekanan darah meningkat Tujuan dari penelitian ini adalah untuk mengetahui pengaruh berat badan terhadap tekanan darah pada lansia.

Metode: Desain penelitian menggunakan observasional analitik dengan pendekatan cross sectional. Penelitian akan dilaksanakan pada Januari–Mei 2019 di wilayah Kelurahan Sumber. Sampel penelitian diambil dengan teknik purposive sampling, yang memenuhi kriteria retriksi sejumlah 40 responden. Instrumen penelitian menggunakan timbangan berat badan digital dan tensimeter raksa yang telah dikalibrasi. Analisis data menggunakan uji korelasi spearman.

Hasil: Penelitian menunjukan bahwa berat badan lansia mayoritas dalam kategori kelebihan berat badan tingkat berat yaitu sebanyak 32 (80%), tekanan darah lansia mayoritas dalam kategori hipertensi (HT derajat I-III) yaitu sebanyak 21 (52.5%). Hasil uji analisis korelasi spearman menunjukan bahwa terdapat hubungan yang signifikan antara berat badan dan tekanan darah lansia dengan nilai r 0.401, p = 0.01 (<0.05).

Kesimpulan: Terdapat hubungan yang signifikan antara berat badan dan tekanan darah lansia.
Model Pembiayaan Syariah Dalam Mengatasi Praktik Sistem Tebasan Di Sentra Padi Nasional
Authors: Hartono Nono
Published: July 2020

The objectives of this study to identify the implementation of tebasan practices, analyze the contribution of the role of Islamic financial institutions and develop a sharia financing model to solve the practice of tebasan. The research method used with a qualitative approach, through interviews with farmers and Islamic financial institutions. The results showed that the practice of the tebasan in Indramayu had been carried out for a long time by the community, this was due to the lack of understanding of Islamic law which made the farmers continue to carry out the practice. In addition, the contribution of Islamic financial institutions to solved the practice has not yet existed. The absence of limited capital human resources and businesses that have large risks are the main factors of Islamic financial institutions have not contributed. Islamic finance which can be a solution to solve the practice of tebasan source non-commercial financing (Al-Qardhul Hasan) and commercial financing (Salam, Musyarakah or Mudharabah).
Determinan Harga Saham Pertambangan di Indonesia
Authors: Astuti Adni Dwi , Anwar Moh Syaiful
Published: July 2020

The purpose of this research is to know the influence of profitability, solvency, and commodity prices on the stock price of mining companies listed on the Indonesia Stock Exchange (IDX) in 2008-2018. Some aspects used in research include financial ratios such as ROE (Return of Equity), EPS (Earning per share of common stock) for variable profitability and DER (Debt to Equity Ratio) for solvency as well as the addition of external factors Like commodity prices to see how it affects the price of the stock. This research is conducted by the documentation method using data from the financial report of the mining company obtained from the Indonesia Stock Exchange website. The analytical methods used in the research are the classical assumption test analysis and the data regression panel. This research uses a data mining company registered in Jakarta Islamic Index (JII) in 2008 – 2018 as 5 companies from 27 registered companies. The results of the Common-Constant estimation method (Pooled Ordinary Least Square/PLS) found that DER and EPS influence the stock price of the mining company partially, While commodity prices do not have a significant effect against the stock price of mining companies. ROE, DER, EPS and commodity prices do not have a significant effect on the stock price of mining companies, it can be demonstrated by the R-Squared 0.150565 value which means the above variables affect only 15.05% and the remaining 84.95% is determined by other variables not researched in this study.
Back-matter
Authors: Siregar Tongku Nizwan
Published: July 2020

back matter Vol. 14 No. 1 March 2020
Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak
Authors: Zhang Xiaolan , Bao Qi , Jia Congjun , Li Chen , Chang Yongfang , Wu Xiaoyun , Liang Chunnian , Bao Pengjia , Yan Ping
Published: July 2020

Background: Long non-coding RNA (lncRNA) as an important regulator has been demonstrated playing an indispensable role in the biological process of hair follicles (HFs) growth. However, their function and expression profile in the HFs cycle of yak are yet unknown. Only a few functional lncRNAs have been identified, partly due to the low sequence conservation and lack of identified conserved properties in lncRNAs. Here, lncRNA-seq was employed to detect the expression profile of lncRNAs during the HFs cycle of yak, and the sequence conservation of two datasets between yak and cashmere goat during the HFs cycle was analyzed. Results: A total of 2884 lncRNAs were identified in 5 phases (Jan., Mar., Jun., Aug., and Oct.) during the HFs cycle of yak. Then, differential expression analysis between 3 phases (Jan., Mar., and Oct.) was performed, revealing that 198 differentially expressed lncRNAs (DELs) were obtained in the Oct.-vs-Jan. group, 280 DELs were obtained in the Jan.-vs-Mar. group, and 340 DELs were obtained in the Mar.-vs-Oct. group. Subsequently, the nearest genes of lncRNAs were searched as the potential target genes and used to explore the function of DELs by GO and KEGG enrichment analysis. Several critical pathways involved in HFs development such as Wnt signaling pathway, VEGF signaling pathway, and signaling pathways regulating pluripotency of stem cells, were enriched. To further screen key lncRNAs influencing the HFs cycle, 24 DELs with differ degree of sequence conservation were obtained via a comparative analysis of partial DELs with previously published lncRNA-seq data of cashmere goat in the HFs cycle using NCBI BLAST-2.9.0+, and 3 DELs of them were randomly selected for further detailed analysis of the sequence conservation properties.Conclusions: This study revealed the expression pattern and potential function of lncRNAs during HFs cycle of yak, which would expand the knowledge about the role of lncRNAs in the HFs cycle. The findings related to sequence conservation properties of lncRNAs in the HFs cycle between the two species may provide valuable insights into the study of lncRNA functionality and mechanism.
Conquering Hypertension in Vietnam- Solutions at Grassroots Level: Study Protocol of a Cluster Randomized Controlled Trial
Authors: Ha Duc , Tran Oanh , Nguyen Hoa , Goldberg Robert , Chiriboga German , Phan Van , Nguyen Cuc , Nguyen Giang , Pham Hien , Nguyen Thang , Le Thanh , Allison Jeroan
Published: July 2020

BackgroundVietnam has been experiencing an epidemiologic transition to that of a low-middle income country with an increasing prevalence of non-communicable diseases. The key risk factors for cardiovascular disease (CVD) are either on the rise or at alarming levels in Vietnam, particularly hypertension (HTN). Inasmuch, the burden of CVD will continue to increase in the Vietnamese population unless effective prevention and control measures are put in place. The objectives of the proposed project are to evaluate the implementation and effectiveness of two multi-faceted community and clinic-based strategies on the control of elevated blood pressure (BP) among adults in Vietnam via a cluster-randomized trial design. MethodsSixteen communities will be randomized to either an intervention (8 communities) or comparison group (8 communities). Eligible and consenting adult study participants with HTN (n = 680) will be assigned to intervention/comparison status based on the community in which they reside. Both comparison and intervention groups will receive a multi-level intervention modeled after the Vietnam National Hypertension Program including education and practice change modules for health care providers, accessible reading materials for patients, and a multi-media community awareness program. In addition, the intervention group only will receive three carefully selected enhancements integrated into routine clinical care: (1) expanded community health worker services; (2) home blood pressure (BP) self-monitoring; and (3) a “storytelling intervention.”. which consists of interactive, literacy-appropriate, and culturally sensitive multimedia storytelling modules for motivating behavior change through the power of patients speaking in their own voice. The storytelling intervention will be delivered by DVD, with serial installments at baseline and at 3, 6, and 9 months after trial enrollment. Changes in BP will be assessed in both groups at several follow-up time points. Implementation outcomes will be assessed as well.DiscussionResults from this full-scale trial will provide health policy makers with practical evidence on how to combat a key risk factor for CVD using a feasible, sustainable, and cost-effective intervention that could be used as a national program for controlling HTN in Vietnam.Trial registration: ClinicalTrials.gov. Registration number: https://clinicaltrials.gov/ct2/show/NCT03590691 (registration date July 17, 2018).Protocol version: 6. Date: 08/15/2019
SPIF process of axisymmetric parts made of AA1060-H14 aluminum alloy tested on 2 axis-NC lathe machine
Authors: Lotfi Ben Said , Bouhamed Abir , Wali Mondher , Kolsi Lioua , Dammak Fakhreddine
Published: July 2020

The authors have withdrawn this preprint due to author disagreement.
Effectiveness of switching between TNF inhibitors in patients with axial spondyloarthritis: is the reason to switch relevant?
Authors: Manica Santiago Rodrigues , Sepriano Alexandre , Pimentel-Santos Fernando M , Gouveia Nélia , Barcelos Anabela , Branco Jaime , Bernardes Miguel , Ferreira Raquel Miriam , Vieira-Sousa Elsa , Barreira Sofia , Vinagre Filipe , Roque Raquel , Santos Helena , Madeira Nathalie , Rovisco João , Daniel Alexandra , Ramiro Sofia
Published: July 2020

Background: To investigate whether the reason to discontinue the first TNF inhibitor (TNFi) affects the response to a second TNFi in axial spondyloartrhtis (axSpA).Methods: Patients with axSpA from the Rheumatic Diseases Portuguese Register (ReumaPt), who discontinued their first TNFi and started a second TNFi between June 2008 and May 2018 were included. Response was assessed by the Ankylosing Spondylitis Disease Activity Score (ASDAS) clinically important improvement (ASDAS-CII), major important improvement (ASDAS-MI), low disease activity (ASDAS-LDA) and inactive disease (ASDAS-ID). The reason for discontinuation of the first TNFi was defined, according to ASDAS-CII as: primary failure (no response ≤6 months); secondary failure (response ≤6 months but lost thereafter); adverse events; other. The association between the reason of discontinuation of the first TNFi and response to the second TNFi over time was assessed in multivariable generalized equation (GEE) models.Results: In total, 193 patients were included. The reason of discontinuation of the first TNFi did not influence the response to a second TNFi, according to the ASDAS-CII. However, a difference was found with more stringent outcomes, e.g. there was a higher likelihood to achieve ASDAS-ID with the second TNFi for patients discontinuing the first TNFi due to secondary failure (OR: 7.3 [(95%CI: 1.9; 27.7]), adverse events (OR: 9.1 [2.5; 33.3]), or other reasons (OR: 7.7 [1.6; 37.9]) compared to primary failure.Conclusion: Patients with axSpA with secondary failure to their first TNFi, compared to those with primary failure, have better response to the second TNFi according to stringent outcomes.