bluuebunny/crossref_metadata_2025 huggingface dataset:
Kollektiivista mallia voidaan soveltaa kasvatustieteiden tohtorikoulutuksessa
Authors: Hakkarainen Kai , Hytönen Kaisa , Makkonen Juho , Lehtinen Erno
Published: September 2020

Yhteisjulkaisuihin perustuva tohtorikoulutuksen kollektiivinen malli on perinteisesti kuulunut luonnontieteisiin. Myös ihmistieteissä ollaan siirtymässä henkilökohtaisista julkaisuista kohti yhteisjulkaisemisen kulttuuria.
Näin johdat Oy Minä Ab:tä
Authors: Laukkarinen Jaana
Published: September 2020

työelämätaidot : sinä oman työelämäsi johtajana / Tarja Surakka & Tomi Rantamäki. [Espoo] : Decanet ; Suomen Palkitsemiskeskus, 2013.
Juokse, jotta pysyt paikallasi
Authors: Anttila Markus
Published: September 2020

Muutoksessa / Katariina Ponteva. Helsinki : Sanoma Pro, 2012.
Työhyvinvointia työtä kehittämällä, ei seikkailemalla
Authors: Keskinen Soili
Published: September 2020

Yhteinen muutos : työhyvinvointia työtä kehittämällä / Marika Schaupp, Annarita Koli, Anna-Leena Kurki & Arja Ala-Laurinaho. Helsinki : Työterveyslaitos, 2013.
Johtajuus tieteiden rajapinnoissa
Authors: Keskinen Soili
Published: September 2020

Johtamisen psykologia : ihmisten johtaminen muuttuvassa työelämässä / Juha Perttula ja Antti Syväjärvi (toim.). Jyväskylä, 2012.
Tilaa mielekkäälle työlle
Authors: LaPointe Kirsi
Published: September 2020

Uramuutos on ajankohtainen monen työtekijän arjessa. Toimijuus eli kyky tehdä valintoja muutostilanteessa ei rajoitu pelkästään työhön, vaan heijastuu myös muihin elämänalueisiin ja identiteettiin.
Kirsi LaPointen väitöskirja Moral struggles, subtle shifts : narrative practices of identity works in career transitions (Aalto-yliopiston kauppakorkeakoulu 2011).
Exploring adipogenic and myogenic circulatory biomarkers of recurrent pressure injury risk for persons with spinal cord injury
Authors: Bogie Kath M , Schwartz Katelyn , Li Youjin , Wang Shengxuan , Dai Wei , Sun Jiayang
Published: September 2020

Purpose: To investigate linkages between circulatory adipogenic and myogenic biomarkers, gluteal intramuscular adipose tissue (IMAT), and pressure injury (PrI) history following spinal cord injury (SCI).

Methods: This is an observational repeated-measures study of 30 individuals with SCI. Whole blood was collected regularly over 2-3 years. Circulatory adipogenic and myogenic gene expression was determined. IMAT was defined as above/below 15% (IMATd) or percentage (IMAT%). PrI history was defined as recurrent PrI (RPrI) or PrI number (nPrI). Model development used R packages (version 3.5.1). Univariate analysis screened for discriminating genes for downstream multivariate and combined models of averaged and longitudinal data for binary (RPrI/IMATd) and finer scales (nPrI/IMAT%).

Results: For adipogenesis, Krüppel-like factor 4 was the top RPrI predictor together with resistin and cyclin D1, and sirtuin 2 was the top IMAT predictor. For myogenesis, the top RPrI predictor was dysferlin 2B, and pyruvate dehydrogenase kinase-4 was the top IMAT predictor together with dystrophin.

Conclusion: Circulatory adipogenic and myogenic biomarkers have statistically significant relationships with PrI history and IMAT for persons with SCI. Biomarkers of interest may act synergistically or additively. Variable importance rankings can reveal nonlinear correlations among the predictors. Biomarkers of interest may act synergistically or additively, thus multiple genes may need to be included for prediction with finer distinction.
Balanço hídrico e erosivibilidade nas microrregiões do Estado da Paraíba, Brasil
Authors: França Manoel Vieira de , Medeiros Raimundo Mainar de , Araújo Wagner Rodolfo de , Holanda Romildo Morant de
Published: September 2020

Objetiva-se aferir as classes hídricas pelo círculo do cenário climático futuro pluvial e térmico do ar, levando-se em conta os cenários médios mensais com redução pluvial de 10% e acréscimo térmico de 1 ºC (cenário otimista = B2) e 20% e 4 ºC (cenário pessimista = A2) e o seu impacto erosivo no solo, visando mostrar os efeitos do aquecimento global através do computo do balanço hídrico e alertar à população sobre a degradação do solo nas área em estudos. As precipitações mensais e anuais foram adquiridas da Superintendência de Desenvolvimento do Nordeste compreendido entre 1912 a 2018, os dados térmicos foram gerados pelo Software Estima-T, para o mesmo período em estudo. Para determinação do fator erosividade aplicou-se a equação proposta por Wischmeier e Smith. Os índices evapotranspirativos registraram acréscimo nas regiões e nos cenários estudados; o poder evaporativo mantiveram em reduções nos cenários B2 e A2, as deficiências e os excedentes hídricos registaram variações de altos e baixos para os cenários. Nos cenários B2 e A2 registraram-se reduções erosivas nas regiões estudadas, significando que a camada superficial do solo praticamente foi carreada tornando-se mais compactos. Os resultados demonstram que nos cenários B2 e A2, advertem situações críticas de condições do solo os quais ocasionarão impactos nos recursos hídricos e nas culturas de cerqueiro.
Expansão urbana e redução de áreas verdes em Salvador/BA: o caso do Parque São Bartolomeu
Authors: Verde Mariane Reis Vila , Santana Leonardo Silvério Gonçalves de , Almeida Priscila Nascimento Ladeia de , Reis Renato Barbosa , Mello Marcia M. Couto , Cavalcante Marília Moreira
Published: September 2020

O tecido urbano das cidades se apresenta como resultante dos processos de interação entre indivíduos e o meio natural, neste sentido, teoricamente, o aspecto da urbanização tende a refletir o progresso e desenvolvimento da sociedade. Entretanto, a segregação social, degradação ambiental e carência de serviços e de infraestrutura compõem as problemáticas comuns de quase todas as grandes metrópoles brasileiras. O objetivo deste artigo é analisar como o processo de expansão da cidade impacta diretamente na degradação do Parque São Bartomoleu, situado na região do Subúrbio Ferroviário de Salvador, Bahia. A metodologia adotada neste artigo abrange a revisão bibliográfica acerca da temática e, desta forma, os resultados obtidos ratificam que a ocupação desordenada possibilita a redução das áreas verdes livres e da qualidade de vida urbana.
Perfil dos visitantes e seus impactos no Parque Estadual da Serra da Tiririca, RJ, Brasil
Authors: Pacheco Benedito Célio , Loretto Diogo , Olifiers Natalie
Published: September 2020

O Parque Estadual da Serra da Tiririca (PESET) recebeu em 2018 aproximadamente 155 mil visitantes e este grande número causa impactos antrópicos. Considerando a importância da conservação da biodiversidade e preservação dos serviços ecossistêmicos nos parques, foi realizado o levantamento do perfil dos visitantes bem como dos impactos antrópicos decorrentes da visitação. Entre 2017 e 2018, foram amostrados 449 visitantes e 28 funcionários através de questionários para obter o perfil dos visitantes e as atividades desenvolvidas durante a visita. A maioria dos visitantes era proveniente de Niterói e Rio de Janeiro (95%), possuíam nível superior incompleto ou acima (68%) e frequentavam o parque nos finais de semana e feriados (72%). Os visitantes não costumavam marcar visita (91%) e não conheciam as regras do parque (72%). O contato com a natureza (44%) e a prática de atividades físicas (26%) foram as principais razões das visitas. Visitantes com maior grau de escolaridade e motivados pelo contato com a natureza, prática de esportes ou atividades religiosas relataram menos impactos negativos durante a visita (P<0,0001). A utilização de atalhos e descarte/presença de resíduos sólidos foi o impacto mais observado/relatado. Recomenda-se ações de educação ambiental combinadas a práticas esportivas para os visitantes, especialmente nos finais de semana e feriados. Essas atividades devem ressaltar a importância de conhecer e respeitar as regras do parque. É importante que os planos de manejo incluam a caracterização do perfil dos visitantes e que este perfil seja monitorado ao longo do tempo, como parte integrante de um manejo adaptativo.
Potential of Beauveria bassiana formulations to control Thaumastocoris peregrinus (Hemiptera: Thaumastocoridae)
Authors: Tedesco Flavia Galvan , Lozano Everton Ricardi , Mazaro Sérgio Miguel , Abati Raiza , Potrich Michele
Published: September 2020

This study evaluated the potential of four formulations of the entomopathogenic fungus Beauveria bassiana for the control of Thaumastocoris peregrinus. For this, the leaves of Eucalyptus dunni were immersed in each delivery of B. bassiana, isolated IBCB 66, and also in sterile distilled water containing Tween 80® (0.01%) (control), totaling five treatments, with five repetitions each. These leaves were placed in germination boxes containing 10 insects in each and, subsequently, kept in an air-conditioned room (27 ± 2 ° C, 60 ± 10% RH, and 12-h photophase). Record longevity for seven days. The experiment was carried out with adults and also with 3rd instar nymphs of T. peregrinus. These formulations were tested for resistance induction, using organic soybean seeds (standard) sown in sand. Ten days after emergence, 40 µL of treatment suspension was competent in 2 mm cuts made on the top of the cotyledon. Phytoalexins and phenylalanine ammonia lyase (PAL) were determined. All formulations caused a reduction in the longevity of T. peregrinus when compared to the control, standing out as formulations T1 and T2, both for adults and for 3rd instar nymphs of T. peregrinus. The T2 expansion also promotes an increase in the production of phytoalexins and PAL. Thus, the IBCB 66 isolate from B. bassiana, supplied T1, has the potential to control nymphs and adults of T. peregrinus and is also a potential resistance inducer.
Zoonotic potential of oral microbiota of capuchins monkeys (sapajus libidinosus)
Authors: Pinheiro Larissa Campos Rodrigues , Sobrinho Junior Enoque Pereira Costa , Nascimento Gildevane Vieira do , Quessada Ana Maria , Abreu Agnys Raquel Sousa , Camapum Jaqueline Lustosa Rodrigues , Morais Noely Martins Bringel de , Silva Filipi Alexandre do Nascimento , Belettini Salviano Tramontin , Rodrigues Marcelo Campos
Published: September 2020

Sapajus libidinosus is a species of primates, popularly known as capuchin monkey. The oral cavity of the monkeys may have pathogenic microbiota for human. Therefore, the study of the microbiota of these species is of great interest in unique health. The objective of the present article was to carry out a survey of the oral microbiota of Sapajus libidinosus, kept in captivity, in the Zoobotanical Park of Teresina (PI, Brazil). Ten chemically immobilized primates were used. Samples were collected from the oral mucosa along the maxillary muco-gingival transition, and these samples were sent to culture and microbiological identification. Most of the microorganisms found were Gram negative and E.coli was the most frequent, followed by Enterobacter spp, Klebsiella spp, Proteus mirabilis, Citrobacter spp.,Morganella morganii, as well as Gram positive bacteria of the type Staphylococcus spp. The data obtained demonstrated the presence of bacterial strains with potential risk of transmission to other animals kept in the park as well as humans in contact with these animals.
A importância da utilização do cateter central de inserção periférica
Authors: Gomes Rayla Oliveira , Lima Thiago Oliveira Sabino , Silva Raylton Aparecido Nascimento , Abreu Vitor Pachelle Lima , Silva Robson Mariano Oliveira , Silva Fabrício Ferreira , Santos Jessica Costa Moreira dos , Ferreira Ruhena Kelber Abrão
Published: September 2020

O cateter venoso central de inserção periférica PICC é um cateter que se insere em uma veia periférica e progride para veia cava superior ou inferior adquirindo características de um cateter central. É um dispositivo que possui diversas versões, com um, dois ou três lumens, é flexível, radiopaco, de paredes lisas e homogêneas, feito de silicone ou poliuretano. Tal dispositivo beneficia no tratamento ao neonato que requer cuidados prolongados.  O presente estudo visa analisar a importância da utilização do Cateter Central de Inserção Periférica – PICC no cuidado a neonatos enfermos, bem como analisar a função da equipe de enfermagem na inserção e manutenção dessa técnica. A metodologia utilizada foi pesquisa bibliográfica com análise de artigos científicos, teses e outras publicações de enfermagem encontrados em bases de dados relacionadas com o tema. Os resultados encontrados a partir dos estudos revisados mostraram que PICC é um dispositivo advindo das novas tecnologias que proporcionam um melhor tratamento aos recém-nascidos que precisam de tratamento prolongado. O enfermeiro e a equipe de enfermagem devem sempre está se atualizando e capacitando para prestar um atendimento humanizado e de qualidade.
Importância e atribuições da gestão em enfermagem nos serviços de terapia renal substitutiva: percepção de enfermeiros
Authors: Castilho Francinéa de Nazaré Ferreira de , Martins Jaqueline Dantas Neres , Maia Camilla Castilho , Maia Giselle Castilho , Pinto Ricardo Figueiredo
Published: September 2020

Objetivo: Descrever a percepção de enfermeiros sobre importância e atribuições da gestão em enfermagem nos serviços de terapia renal substitutiva. Método: Pesquisa descritiva-exploratória realizada em serviços de diálise de Belém e Ananindeua com enfermeiros gestores desse setor, mediante entrevista semi-estruturada, sendo realizada a interpretação dos dados com base na análise de conteúdo de Bardin. Resultados: A pesquisa foi realizada com 8 enfermeiros gestores do serviço de diálise. Surgiram 3 categorias a partir da análise: Categoria 1- Compreensão do enfermeiro sobre a gerência dos serviços de enfermagem em diálise; Categoria 2- Categoria 2- As atribuições do enfermeiro no serviço de diálise; Categoria 3- A importância da gerência de enfermagem nos serviços de diálise. Conclusão: Os enfermeiros conhecem suas atribuições e a importância de seu trabalho, no entanto, citam adversidades como empecilhos na melhoria de qualidade dos cuidados.
Abordagem cirúrgica de pilomatricoma – relato de caso
Authors: Cavalcante Mateus Barros , Rodrigues Éwerton Daniel Rocha , Uchôa Caio Pimenteira , Silva Joana de Ângelis Alves , Rocha Caroline Brigida Sá , Torres Luiz Henrique Soares , Silva Emanuel Dias de Oliveira e
Published: September 2020

Pilomatricoma ou epitelioma calcificante de Malherbe é uma neoplasia cutânea benigna rara, com origem nas células da matriz do folículo piloso que surge na maioria dos casos durante a infância ou adolescência. Clinicamente apresentam-se frequentemente como nódulos assintomáticos, com coloração geralmente semelhante à pele normal, localizados predominantemente na cabeça, pescoço ou extremidades superiores, de consistência habitualmente dura, crescimento lento e na maioria dos casos solitárias. A excisão cirúrgica é geralmente recomendada para os pilomatricomas, para prevenir o seu crescimento ou comprometimento estético, não havendo recidiva como regra. O presente relato tem por objetivo a apresentação de um caso de pilomatricoma e sua abordagem cirúrgica intra-oral, bem como discutir a literatura pertinente sobre o tema. O relato de caso descreve paciente com queixa de nódulo na bochecha. O anatomopatológico diagnosticou pilomatricoma. Após a cirurgia, a paciente evoluiu sem complicações, sendo acompanhada ambulatorialmente. Por apresentar extensas possibilidades de diagnóstico diferencial o diagnóstico clínico isolado se torna difícil. Sendo assim, é importante que o profissional esteja familiarizado com essa neoplasia.
Viabilidade econômica e ambiental da substituição do gás liquefeito de petróleo a partir da recuperação do calor gerado na produção de ar comprimido
Authors: Carvalho Alisson Lara de , Oliveira Júlia Assunção de Castro , Brito Jorge Nei , Assunção Teresa Cristina Bessa Nogueira
Published: September 2020

Diversas empresas utilizam o gás liquefeito de petróleo (GLP), comumente conhecido como “gás de cozinha” para realizar o aquecimento da água dos chuveiros de vestiários. O uso do GLP para esta finalidade representa um custo elevado, no entanto, empresas que possuem um sistema de produção de ar comprimido poderiam recuperar o calor gerado no processo de compressão do ar atmosférico e utilizá-lo como substituinte do GLP para o aquecimento da água, reduzindo custos e impactos ambientais. Neste sentido, objetivou-se analisar a viabilidade econômica e ambiental da recuperação do calor gerado na produção de ar comprimido em substituição ao GLP para o aquecimento da água dos chuveiros em uma indústria química no estado de Minas Gerais. Incialmente foram orçados os custos do consumo de GLP para o aquecimento dos chuveiros e da implantação do projeto de recuperação do calor produzido pelos compressores. Os resultados deste estudo de viabilidade apontaram que a implantação deste tipo sistema de recuperação de calor produzido durante a compressão do ar comprimido é economicamente viável. Além disso, esta substituição promoveria o aumento da eficiência energética global desta indústria, bem como uma redução da emissão de CO2. Esta análise também demonstrou que a inclusão deste tipo de instalação de recuperação de calor no projeto inicial pode influenciar na localização dos compressores, reduzindo os gastos com isolamento térmico e tubulações e aumentando a eficiência da recuperação do calor produzido.
Um conto de fadas nos 5 reinos dos seres vivos: ensinando ciências na alfabetização
Authors: Silva Aline da , Deccache-Maia Eline
Published: September 2020

A relação ciência e arte no ensino tem enorme potencial historicamente evidenciado  produzindo resultados interessantes, como os aqui apresentados. Nossas atividades, voltadas ao ensino de ciências, centraram-se na temática dos cinco reinos dos seres vivos em uma turma do 1º ano do Ensino Fundamental I, aliando perspectivas construtivista, da aprendizagem significativa e da ludicidade. O foco interdisciplinar auxiliou na elaboração de uma história em quadrinhos, permitindo verificar como ocorreram a assimilação do tema, a promoção da alfabetização propriamente dita e a científica. A metodologia de ensino foi realizada em etapas e o seu acompanhamento feito por meio da pesquisa qualitativa pela observação participante. O tema proposto contribuiu surpreendentemente para as aulas, pois as crianças sentiram-se contempladas pelas atividades interdisciplinares, podendo ser observado que a inclusão de temas científicos desde cedo, respeitando as especificidades da faixa etária dos alunos, não onerou o seu desenvolvimento, ao contrário, colaborou para o seu incremento.
Elaboração e caracterização de produto farináceo a partir da folha do umbuzeiro (Spondias tuberosa Arruda)
Authors: Ferreira Sânzia Viviane de Farias , Campos Ana Regina Nascimento , Medeiros Maria Franco Trindade
Published: September 2020

O objetivo do trabalho foi à elaboração e caracterização física e química de um produto farináceo produzido a partir das folhas do umbuzeiro (Spondias tuberosa Arruda) utilizando diferentes métodos de secagem.  Os procedimentos experimentais consistiram em produção de farinhas a partir da secagem de 30 g de folhas em estufa de circulação de ar à 60 °C por 6 h e em forno micro-ondas (FMO) com potência de 100% em ciclo único de 2 min e 30 s. Os parâmetros físicos e químicos avaliados tanto nas folhas in natura, quanto nas farinhas elaboradas foram: teor de água (TA), atividade de água, pH, sólidos solúveis totais (SST), proteína bruta (PB), resíduo mineral fixo (RMF) e quantificação de minerais. O valor médio de TA da folha do umbuzeiro in natura (75,06%) foi superior ao encontrado nas farinhas, que apresentaram valores próximos entre si, em torno de 6,00%, bem como os valores de atividade de água, sendo para as folhas in natura (0,987), farinha em estufa (0,330) e farinha em FMO (0,323). As farinhas analisadas apresentaram ainda, pH ácido, valores de SST de 7,17 °Brix (estufa) e 10,27 °Brix (FMO), percentual de PB de 9,00% (estufa) e 8,60% (FMO). Além de valores de RMF (acima de 12,00%) indicando elevado teor mineral, com destaque para o Ca, K, Mg, Fe, Zn e Cu. O processo de secagem mostrou-se viável, produzindo farinhas com valores de TA dentro das normas vigentes e rendimentos semelhantes para os dois métodos de secagem empregados (23,0%).
Orange albedo flour as a fat replacer in beef burgers: adding value to citrus industry by-products
Authors: Silva Lívia Bicalho Ferreira , Miranda Camila Neves , Santos Mirian dos , Pereira Patrícia Aparecida Pimenta , Cunha Luciana Rodrigues da , Vieira Silvia Mendonça , Gandra Kelly Moreira Bezerra
Published: September 2020

Dietary fiber is an important component to improve the nutritional appeal of meat products, and it could be obtained from by-products of the citrus industry. Considering that orange albedo was not sufficiently addressed in meat products, the purpose of this work was to evaluate the influence of the orange albedo flour as an animal fat substitute in beef burgers. Five formulations were developed with different substitutions of pork fat by the orange albedo flour (0; 25; 50; 75; and 100%). The analyses carried out were the proximal composition of orange albedo flour and beef burgers and the cooking yield, shrinkage, pH, color, sensory acceptance, and purchase intent of the beef burgers. The results showed that the percentage of lipids was reduced by up to 70%, however, the yield parameters were negatively affected by the inclusion of the orange albedo flour: the higher the amount of flour added, lower was the water retention capacity and higher was the shrinkage rate. Concerning sensory analysis, the formulations that pork back fat was substituted by 25 and 50% of orange albedo flour were the most acceptable for all sensory attributes and purchase intention, characterizing themselves as viable alternatives both of the nutritional and sensory aspects.
Percepção da Equipe Multiprofissional sobre a Atuação do Terapeuta Ocupacional na Unidade de Terapia Intensiva
Authors: Gomes Sandy de Oliveira Lemos , Belo Amanda Cavalcanti , Marcelino Juliana Fonsêca de Queiroz , Santos Marília de Arruda dos , Silva Lucas de Paiva , Rabelo Aneide Rocha de Marcos
Published: September 2020

Objetivo: Este estudo tem como objetivo conhecer a percepção da equipe multiprofissional da unidade de terapia intensiva acerca da atuação do terapeuta ocupacional como parte da equipe e qual a compreensão desses profissionais sobre sua atuação junto ao paciente e seus familiares. Metodologia: Trata-se de um estudo transversal, qualitativo, realizado em uma unidade de terapia intensiva de um Hospital Universitário, na Região Metropolitana de Recife, com 14 funcionários da unidade. Foram realizadas entrevistas com os participantes sobre os conhecimentos acerca da Terapia Ocupacional e sua atuação no serviço. Resultados: A partir da análise dos discursos dos participantes foram elencadas as categorias: Funcionalidade, Atividade de Vida Diária, Cognição, Família, Atividade/Recurso, Comunicação e Equipe, as quais apresentam ligação direta ao fazer do terapeuta ocupacional neste espaço. Conclusão: Apesar da ainda pequena visibilidade da ação dos profissionais da terapia ocupacional na unidade de terapia intensiva, os demais profissionais que compõem a equipe desta unidade, manifestaram sua percepção sobre a atuação deste profissional a partir do uso da atividade, visando a funcionalidade e independência do sujeito, no seu retorno às atividades cotidianas, minimizando as possíveis sequelas cognitivas e físicas.
Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases
Authors: Kim Yun Seok , Kim Sang Geon
Published: September 2020

Alcoholic and non-alcoholic liver diseases begin from an imbalance in lipid metabolism in hepatocytes as the earliest response. Both liver diseases share common disease features and stages (i.e., steatosis, hepatitis, cirrhosis, and hepatocellular carcinoma). However, the two diseases have differential pathogenesis and clinical symptoms. Studies have elucidated the molecular basis underlying similarities and differences in the pathogenesis of the diseases; the factors contributing to the progression of liver diseases include depletion of sulfhydryl pools, enhanced levels of reactive oxygen and nitrogen intermediates, increased sensitivity of hepatocytes to toxic cytokines, mitochondrial dysfunction, and insulin resistance. Endoplasmic reticulum (ER) stress, which is caused by the accumulation of misfolded proteins and calcium depletion, contributes to the pathogenesis, often causing catastrophic cell death. Several studies have demonstrated a mechanism by which ER stress triggers liver disease progression. Autophagy is an evolutionarily conserved process that regulates organelle turnover and cellular energy balance through decomposing damaged organelles including mitochondria, misfolded proteins, and lipid droplets. Autophagy dysregulation also exacerbates liver diseases. Thus, autophagy-related molecules can be potential therapeutic targets for liver diseases. Since ER stress and autophagy are closely linked to each other, an understanding of the molecules, gene clusters, and networks engaged in these processes would be of help to find new remedies for alcoholic and non-alcoholic liver diseases. In this review, we summarize the recent findings and perspectives in the context of the molecular pathogenesis of the liver diseases.
NIEKOĽKO POZNÁMOK K NÁMIETKE ZAUJATOSTI V TRESTNOM KONANÍ
Authors: Floriš Martin
Published: September 2020

Právo na spravodlivé súdne konanie vedené pre nezávislým a nestranným súdom, analogicky rozšíriteľné aj o rozmer nezávislosti a nestrannosti orgánov činných v trestnom konaní (s výnimkou vzťahov nadriadenosti a podriadenosti, o ktorej v prípade súdu 2 nemožno hovoriť), je dlhodobo verejne diskutovanou témou, o aktuálnosti ktorej svedčia aj aktuálne znepokojivé zistenia o zlyhávaní nezávislosti minimálne časti súdnej moci, či (opäť) minimálne individuálnych zlyhaní sudcov ako osôb, ktorých mandát má a v budúcnosti musí byť garantom práva na spravodlivý proces. Pokiaľ ide o nestrannosť, táto objektívne musí byť súčasťou právnej kultúry demokratického štátu. Pre úplnosť je však nutné dodať, že právna úprava analyzuje len stav de lege ferenda a jej skutočné pretavenie bude vždy aspoň čiastočne závislé od osôb vykonávateľov štátnej moci, čo však tomuto článku nebráni analyzovať zákonom predpokladaný postup v prípade konania o námietke zaujatosti v trestnom konaní.
TOPLUM SAĞLIĞININ KORUNMASI BAĞLAMINDA BİR SOSYAL SORUMLULUK VE BİLİNÇLENDİRME KAMPANYASI: ANOREKSİYA NERVOZA FENOMENİ
Authors: GÜMÜŞ Çağrı , ALVER Elmas
Published: September 2020

Toplum gereksinimleri baz alınarak oluşturulan sosyal sorumluluk proje ve kampanyaları sağlık, sosyal, ekonomik, kültürel, eğitim vb. gibi bir çok alanda ihtiyaçlara cevap vererek toplumsal farkındalık ve dayanışmanın kazandırılmasına yönelik bir bilinç oluşturulmasını hedeflemektedir. Buradaki temel amaç toplumsal faydadır. Kişisel çıkarlar gözetilmeksizin ele alınan toplumsal sorunlara olanaklar çerçevesinde çözüm üretilerek toplumun yüksek yararı hedeflenmektedir. Günümüzde artarak yaygınlaşan ve toplum sağlığı bakımından bir sağlık problemi haline gelen hastalıklardan biri anoreksiya nervozadır. Yeme davranışının ciddi olarak bozulduğu özellikle de genç bireylerde görülen yeme bozukluklarından biri olan anoreksiya nervoza, sık rastlanan ve ruhsal sorunların yanında bedensel sorunların da eşlik ettiği bir tanı grubudur. Yapılan çalışmalarda anoreksiya nervozanın yaşam boyu prevelansı ergen ve genç yetişkinlerde %2 ve %3 olarak belirtilmiştir. Anoreksiya nervozanın özellikle son zamanlarda giderek yükselişe geçmesi toplum sağlığı açısından bir risk oluşturmaktadır. Bu yüzden bu çalışmada, anoreksiya nervoza ile mücadele konusunda bilinçlendirme ve farkındalık kampanyası düzenlenmesinin toplumun hastalığa karşı bilinçlendirilmesi ve hastalığın önlenmesi açısından yararlı olacağı düşünülerek anoreksiya nervoza olgusu üzerinden bir sosyal sorumluluk ve bilinçlendirme kampanyası oluşturulmuştur. Oluşturulan bu kampanyada temel amaç, kadınların beden görünümleriyle ilgili daha az negatif düşünceye sahip olarak olumlu beden algısının oluşturulması ve böylece fiziksel görünümlerine daha pozitif yaklaşmaları sayesinde diyet, aşırı egzersiz vb. gibi konularda daha az meşguliyet edinmeleridir.
DİNLEME/İZLEME STRATEJİLERİNE YÖNELİK KARŞILAŞTIRMALI BİR ÇALIŞMA: PROGRAM VE DERS KİTAPLARI
Authors: SÜĞÜMLÜ Üzeyir , YÜCE Sema Nur
Published: September 2020

Araştırmanın amacı, Türkçe Dersi Öğretim Programı’nda (2019) yer alan dinleme/izleme stratejileri ile ortaokul Türkçe ders kitaplarında yer alan dinleme/izleme stratejilerini karşılaştırmaktır. Öğretim programı ile ders kitaplarının uyumu, öğretimin niteliğini doğrudan etkilemektedir. Türkçe Dersi Öğretim Programı’nda (2019) yer alan dinleme/izleme stratejileri ile ortaokul Türkçe ders kitaplarında yer alan dinleme/izleme stratejilerinin karşılaştırılması, program ile ders kitapları arasındaki tutarlılığın belirlenmesi açısından önemli görülmektedir. Araştırma, nitel araştırma yöntemlerinden durum çalışması ile gerçekleştirilmiştir. Araştırmanın çalışma materyallerini Türkçe Dersi Öğretim Programı (2019) ile ortaokul (5, 6, 7 ve 8. Sınıf) Türkçe ders kitapları oluşturmaktadır. Araştırmanın veri toplama araçlarını program ve ders kitaplarında yer alan dokümanlar oluşturmaktadır. Araştırmanın verileri, doküman incelemesi yoluyla toplanmıştır. Araştırmada veri toplama işleminde İlk olarak programdaki ortaokul düzeylerine yönelik dinleme/izleme stratejileri belirlenmiştir. Bu işlemin ardından ortaokul Türkçe ders kitaplarında yer alan dinleme/izleme stratejilerine yönelik yönerge ve etkinlik uygulamaları incelenmiştir. Son olarak programdaki veriler ile ders kitaplarındaki veriler karşılaştırılarak araştırmanın bulgularına ulaşılmıştır. Araştırmanın verileri, içerik analizi ile çözümlenmiştir. Ders kitaplarındaki dinleme/izleme stratejilerine yönelik yönerge ve etkinlik uygulamaları, programdaki dinleme/izleme stratejilerine göre sınıflandırılmıştır. Araştırma ile Türkçe Dersi Öğretim Programı’nda (2019) yer alan dinleme/izleme stratejileri ile ortaokul Türkçe ders kitaplarında yer alan dinleme/izleme stratejilerinin tutarlı olmadığı sonucuna ulaşılmıştır. Araştırma sonucundan harektle dinleme/izleme stratejilerinin program ve ders kitaplarındaki tutarlığının sağlanması önerisi geliştirilmiştir.
Iliac Artery Dissection: A Case Report
Authors: Ekmekyapar Muhammed , Oğuztürk Hakan , Ekmekyapar Tuba , Gürbüz Şükrü , Derya Serdar
Published: September 2020

Introduction: Iliac artery aneurisms are generally
observed in association with abdominal aortic aneurisms Iliac artery dissection
happens to be one of the rarely encountered cases, and very few cases have been
reported in literature.

Case: A male, 34-years old patient applied
to the emergency service with complaints of abdominal pain and paresthesia in
his left leg. There was no pain or loss of strength in the left leg
of the patient, but there was a numbness described by the patient himself The computerized
brain tomography of the patient was considered as normal, but his abdominal
ultrasonography was reported as “an aneurismal dilatation in both iliac artery on
the bifurcation level on a nearly 3 cm-segment, reaching up to 3 cm at the
widest section and a mural thrombus reaching up to 70% stenosis within the vein
lumen were observed”. Thereon, the patient went through a CT-angiogram, and as
a result, dissection was observed in the left iliac artery together with
aneurismal dilatation and mural thrombus in both iliac arteries. The
patient was hospitalized in the intensive care unit of cardiovascular surgery
clinic. The
cardiovascular surgery clinic did not plan any surgical operation for the
patient, and the patient whose medical treatment was organized was discharged 5
days later.

Conclusion: In regards to the
patients who apply to emergency services with complaints of abdominal pain,
numbness in extremities, acute abdomen or neurologic symptoms atypically seen
like loss of strength, we should also keep in mind aortic dissection and/or
iliac artery dissection among our preliminary diagnoses.
Energy Drinks Induced Atrial Fibrillation
Authors: Zorlu Çağrı
Published: September 2020

Introduction: Atrial fibrillation (AF) is most common in adulthood supraventricular arrhythmia. Some of our ways of life the occurrence of this arrhythmia possible. Recently, it is common to consume energy drinks (ED), especially among young people. Caffeine is found in energy drinks. Their adverse effects, not yet completely known, are usually considered secondary to a high concentration of caffeine. Here we focus on a particular acute cardiac complication of EDs overconsumption: atrial fibrillation.

Case report: A 23-year-old man, was referred to our emergency department for dyspnea, palpitations, and anxiety. The patient had a negative family, personal, and pharmacological history. About two hours before, he has consumed 750ml of ED. At admission, blood pressure was 104/62. An ECG revealed a high rate of atrial fibrillation at 162bpm. Laboratory investigation revealed that complete blood count and routine biochemical blood levels were within normal limits. Transthoracic echocardiogram excluded the presence of cardiac disease, the left atrium was slightly dilated, as expected. According to guidelines patient was treated with propafenone and recovered a normal sinus rhythm.

Conclusion: As in our case, PAF can occur due to ED consumption, and awareness about this adverse effect of ED consumption is important.
Administration of Different Derivatives of Oliveria decumbens Improves Innate Immunity of Nile Tilapia (Oreochromis niloticus) Without Affecting Fish Growth and Blood Biochemical Parameters
Authors: JAALI Soheila , VAZIRZADEH Arya , AKHLAGHI Mostafa , KARAMI Akbar
Published: September 2020

The objectives of this study were to investigate the effects of Oliveria decumbens as a medicinal herb with reported immunostimulatory potential on the growth, immunity status and health of Nile tilapia (Oreochromis niloticus). In an eight- week trial, fish (45 ± 5 g) were randomly divided into 13 treatments as follows: in 10 treatments fish were fed on diets containing 0 (control), 0.01, 0.1 and 1% of O. decumbens extract and essential oil and their 1:1 combinations. Also, in three treatments fish received plant hydrolate at doses of 312.5, 625 and 1250 ppm as bath treatment. At the end of experiment, blood samples were taken for immunological and biochemical measurements. All treated fish showed comparable growth performance to those received control diet. The highest levels of respiratory burst activity were observed in extract 1% group. Similarly the serum lysozyme levels were significantly affected by essential oil and extract supplemented diets. Fish received plant hydrolate at dose 312.5 ppm showed the highest significant protein level. Also, the globulin levels were increased in group fed on diet containing extract 1%. Plant supplementation had no negative effects on the fish health biochemical indices including cholesterol, triglyceride, alkaline phosphatase and aminotransferase enzymes. In conclusion, the results of this study showed that application of O. decumbens derivatives improved the immunity of Nile tilapia without adverse effects on fish growth and health.
Pencegahan Konstipasi pada Ibu Nifas dengan Early Exercise
Authors: Laili Uliyatul , Nisa Fauziyatun
Published: September 2020

In Indonesia, many postpartum mothers experience constipation. Some of the contributing factors include less of movement after childbirth (early mobilization), poor nutritional intake, low fluid intake, narcotic-containing pain relievers leaving the intestines and periodic spasms of the small intestine. The purpose of this study was to find out the effect of giving care in the form of early exercise or early physical exercise in an effort to prevent constipation during the puerperium. The research method used was quasi-experiment; with the population were postpartum mothers on the first day up to the fifth day. Data collections were done by questionnaire and observations then tested by Mann Whitney test. The result of this study is that there was no effect between giving care in the form of early exercise to the incidence of constipation in postpartum mothers, a significance value of 0.678> 0.005. The conclusion of this study is that there were many other factors that influence the incidence of constipation in addition to activity factors, namely anxiety, suture injuries, current and past labor history and nutritional intake.
An Open-Source Social Robot Based on Compliant Soft Robotics for Therapy with Children with ASD
Authors: Casas-Bocanegra Diego , Gomez-Vargas Daniel , Pinto-Bernal Maria J. , Maldonado Juan , Munera Marcela , Villa-Moreno Adriana , Stoelen Martin F. , Belpaeme Tony , Cifuentes Carlos A.
Published: September 2020

Therapy with robotic tools is a promising way to help improve verbal and nonverbal communication in children. The robotic tools are able to increase aspects such as eye contact and the ability to follow instructions and to empathize with others. This work presents the design methodology, development, and experimental validation of a novel social robot based on CompliAnt SofT Robotics called the CASTOR robot, which intends to be used as an open-source platform for the long-term therapy of children with autism spectrum disorder (CwASD). CASTOR integrates the concepts of soft actuators and compliant mechanisms to create a replicable robotic platform aimed at real therapy scenarios involving physical interaction between the children and the robot. The validation shows promising results in terms of robustness and the safety of the user and robot. Likewise, mechanical tests assess the robot’s response to blocking conditions for two critical modules (i.e., neck and arm) in interaction scenarios. Future works should focus on the validation of the robot’s effectiveness in the therapy of CwASD.
Abilities of Canine Shelter Behavioral Evaluations and Owner Surrender Profiles to Predict Resource Guarding in Adoptive Homes
Authors: McGuire Betty , Orantes Destiny , Xue Stephanie , Parry Stephen
Published: September 2020

Some shelters in the United States consider dogs identified as food aggressive during behavioral evaluations to be unadoptable. We surveyed adopters of dogs from a New York shelter to examine predictive abilities of shelter behavioral evaluations and owner surrender profiles. Twenty of 139 dogs (14.4%) were assessed as resource guarding in the shelter. We found statistically significant associations between shelter assessment as resource guarding and guarding reported in the adoptive home for three situations: taking away toys, bones or other valued objects; taking away food; and retrieving items or food taken by the dog. Similarly, owner descriptions of resource guarding on surrender profiles significantly predicted guarding in adoptive homes. However, positive predictive values for all analyses were low, and more than half of dogs assessed as resource guarding either in the shelter or by surrendering owners did not show guarding post adoption. All three sources of information regarding resource guarding status (surrender profile, shelter behavioral evaluation, and adopter report) were available for 44 dogs; measures of agreement were in the fair range. Thus, reports of resource guarding by surrendering owners and detection of guarding during shelter behavioral evaluations should be interpreted with caution because neither source of information consistently signaled guarding would occur in adoptive homes.
Figainin 1, a Novel Amphibian Skin Peptide with Antimicrobial and Antiproliferative Properties
Authors: Santana Carlos José Correia , Magalhães Ana Carolina Martins , dos Santos Júnior Agenor C. M. , Ricart Carlos André Ornelas , Lima Beatriz D. , Álvares Alice da Cunha Morales , Freitas Sonia Maria de , Pires Osmindo Rodrigues , Fontes Wagner , Castro Mariana S.
Published: September 2020

Amphibian skin secretions are abundant in bioactive compounds, especially antimicrobial peptides. These molecules are generally cationic and rich in hydrophobic amino acids, have an amphipathic structure and adopt an α-helical conformation when in contact with microorganisms membranes. In this work, we purified and characterized Figainin 1, a novel antimicrobial and antiproliferative peptide from the cutaneous secretion of the frog Boana raniceps. Figainin 1 is a cationic peptide with eighteen amino acid residues—rich in leucine and isoleucine, with an amidated C-terminus—and adopts an α-helical conformation in the presence of trifluoroethanol (TFE). It displayed activity against Gram-negative and especially Gram-positive bacteria, with MIC values ranging from 2 to 16 µM, and showed an IC50 value of 15.9 µM against epimastigote forms of T. cruzi; however, Figanin 1 did not show activity against Candida species. This peptide also showed cytolytic effects against human erythrocytes with an HC50 of 10 µM, in addition to antiproliferative activity against cancer cells and murine fibroblasts, with IC50 values ranging from 10.5 to 13.7 µM. Despite its adverse effects on noncancerous cells, Figainin 1 exhibits interesting properties for the development of new anticancer agents and anti-infective drugs against pathogenic microorganisms.
Endotoxin Tolerance in Abdominal Aortic Aneurysm Macrophages, In Vitro: A Case–Control Study
Authors: Meital Lara T. , Windsor Mark T. , Maynard Alesiya E. , Schulze Karl , Magee Rebecca , O’Donnell Jill , Jha Pankaj , Meital Chaim Y. , Perissiou Maria , Coverdale Steven , Golledge Jonathan , Kuballa Anna V. , Bailey Tom G. , Askew Christopher D. , Russell Fraser D.
Published: September 2020

Macrophages are implicated in the pathogenesis of abdominal aortic aneurysm (AAA). This study examined the environmentally conditioned responses of AAA macrophages to inflammatory stimuli. Plasma- and blood-derived monocytes were separated from the whole blood of patients with AAA (30–45 mm diameter; n = 33) and sex-matched control participants (n = 44). Increased concentrations of pro-inflammatory and pro-oxidant biomarkers were detected in the plasma of AAA patients, consistent with systemic inflammation and oxidative stress. However, in monocyte-derived macrophages, a suppressed cytokine response was observed in AAA compared to the control following stimulation with lipopolysaccharide (LPS) (tumor necrosis factor alpha (TNF-α) 26.9 ± 3.3 vs. 15.5 ± 3.2 ng/mL, p < 0.05; IL-6 3.2 ± 0.6 vs. 1.4 ± 0.3 ng/mL, p < 0.01). LPS-stimulated production of 8-isoprostane, a biomarker of oxidative stress, was also markedly lower in AAA compared to control participants. These findings are consistent with developed tolerance in human AAA macrophages. As Toll-like receptor 4 (TLR4) has been implicated in tolerance, macrophages were examined for changes in TLR4 expression and distribution. Although TLR4 mRNA and protein expression were unaltered in AAA, cytosolic internalization of receptors and lipid rafts was found. These findings suggest the inflamed, pro-oxidant AAA microenvironment favors macrophages with an endotoxin-tolerant-like phenotype characterized by a diminished capacity to produce pro-inflammatory mediators that enhance the immune response.
A Rule-Based System for Quality Control in Brake Disc Production Lines
Authors: Febriani Risky Ayu , Park Hong-Seok , Lee Chang-Myung
Published: September 2020

Currently, challenges in quality improvement have driven various enterprises to create quality management systems in smart factories. The development of quality management systems enables quality control for reviewing product quality, identification, and eliminating product failures. However, process adjustment in quality control decisions may be hard to determine when failures are detected. To overcome this problem, an expert system (ES) that applies the failure mode and effects analysis (FMEA) method for developing quality control systems in brake disc production lines is considered. This quality control system concentrates on analyzing product defects that occur frequently in the production line and will lead to an improved performance of the braking system; the selected product defects are disc thickness variation (DTV), runout, and parallelism. This quality control system developed two modules, the designed FMEA (DFMEA) and component FMEA, which apply a rule-based algorithm for selecting actions. We propose the rules of configuration into the expert system code. The results indicate that the operator can carry out a quality control system with decision-making that can be supported by intelligent searching and reasoning in an expert system.
Study on Reinforcement Learning-Based Missile Guidance Law
Authors: Hong Daseon , Kim Minjeong , Park Sungsu
Published: September 2020

Reinforcement learning is generating considerable interest in terms of building guidance law and solving optimization problems that were previously difficult to solve. Since reinforcement learning-based guidance laws often show better robustness than a previously optimized algorithm, several studies have been carried out on the subject. This paper presents a new approach to training missile guidance law by reinforcement learning and introducing some notable characteristics. The novel missile guidance law shows better robustness to the controller-model compared to the proportional navigation guidance. The neural network in this paper has identical inputs with proportional navigation guidance, which makes the comparison fair, distinguishing it from other research. The proposed guidance law will be compared to the proportional navigation guidance, which is widely known as quasi-optimal of missile guidance law. Our work aims to find effective missile training methods through reinforcement learning, and how better the new method is. Additionally, with the derived policy, we contemplated which is better, and in which circumstances it is better. A novel methodology for the training will be proposed first, and the performance comparison results will be continued therefrom.
A Cloud-Based UTOPIA Smart Video Surveillance System for Smart Cities
Authors: Yoon Chel-Sang , Jung Hae-Sun , Park Jong-Won , Lee Hak-Geun , Yun Chang-Ho , Lee Yong Woo
Published: September 2020

A smart city is a future city that enables citizens to enjoy Information and Communication Technology (ICT) based smart services with any device, anytime, anywhere. It heavily utilizes Internet of Things. It includes many video cameras to provide various kinds of services for smart cities. Video cameras continuously feed big video data to the smart city system, and smart cities need to process the big video data as fast as it can. This is a very challenging task because big computational power is required to shorten processing time. This paper introduces UTOPIA Smart Video Surveillance, which analyzes the big video images using MapReduce, for smart cities. We implemented the smart video surveillance in our middleware platform. This paper explains its mechanism, implementation, and operation and presents performance evaluation results to confirm that the system worked well and is scalable, efficient, reliable, and flexible.
Efficient Verification of Cryptographic Protocols with Dynamic Epistemic Logic
Authors: Chen Xiaojuan , Deng Huiwen
Published: September 2020

The security of cryptographic protocols has always been an important issue. Although there are various verification schemes of protocols in the literature, efficiently and accurately verifying cryptographic protocols is still a challenging research task. In this work, we develop a formal method based on dynamic epistemic logic to analyze and describe cryptographic protocols. In particular, we adopt the action model to depict the execution process of the protocol. To verify the security, the intruder’s actions are analyzed. We model exactly the protocol applying our formal language and give the verification models according to the security requirements of this cryptographic protocol. With analysis and proof on a selected example, we show the usefulness of our method. The result indicates that the selected protocol meets the security requirements.