bluuebunny/crossref_metadata_2025 huggingface dataset:
SPECTRUM OF SEPTORHINOPLASTY-AN OBSERVATIONAL PROSPECTIVE STUDY
Authors: Natarajan Dhinakaran , Ramamoorthy Radhakrishnan Kailasam , Balakrishnan Ramanathan
Published: January 2023

The septoplasty makes the nose altered and improved.. The shape and contour of the nose are greatly influenced by the nasal septum, The septorhinoplasty is to improve the appearance of nose (rhinoplasty) and to improve how you breathe through nose (septoplasty). It involves operating on the bones and cartilage that give shape and structure to nose and and making septum straight. The nasal septum is the cartilage and bone in nose. The septum divides the nasal cavity into a right and left side. The evaluation and effectiveness of spectrum of septrorhinoplasty on quality of life has been analysed through qualitative questionories with the patient who underwent surgery. The subject group comprised with majority of males (15 males) and 10 females. The age ranged between 8 and 50 years among those who presented to the rhinoplasty The average increase in patient satisfaction after surgery was 44.8+13, from a mean preoperative score of 38.9 + 11 to a postoperative score of 82.75+17.2.This study demonstrates that, despite being a complicated treatment, rhinoplasty has a positive effect on both the appearance and functionality of the nose.
DEVELOPMENT OF A WEB APPLICATION WITH THE OBJECTIVE OF FACILITATING DATA MANAGEMENT FOR BUSINESS INTELLIGENCE
Authors: Carlos Pinto Souza Jean , Da Conceicao Pinheiro Matheus , Rogerio Morais Marinho Carlos , Silva De Souza Pinheiro Jaqueline , Cristiano Abreu Da Silva Odair
Published: January 2023

Everyday thousands of data is generated, but most are lost or stored improperly, when this happens, no longer as data is converted into information, it will not be useful, and may even generate losses rather than gains. To solve these problems, a Demand Management System (SGD) was developed for the internet. The web system comes with the objective of making this information available at any time, creating a system that will manage and collect data to facilitate the creation of Business Intelligence models.
SOBRERREPRESENTATIVIDAD DEL PODER LEGISLATIVO DEL ESTADO DE CAMPECHE
Authors:   Master in Higher Education, Academic Researcher, Faculty of Political Science, Autonomous University of Campeche., Dzib Cambranis Josue , Monserrat Llanes Chiquini Charlotte ,   Ph in Administration Sciences, Academic Researcher, Faculty of Administration and Finance, Autonomous University of Campeche., Gerardo Trejo Llanes Rafael ,   Masters in Administrative Engineering, Academic Researcher, Inter-American University for Development (UNID)Campechecampus., Ashanty De Las Maravillas Del Valle Zetina Isis ,   Masters Degree in Criminal Law Sciences, Academic Researcher Technological of Campeche.
Published: January 2023

Esta investigacion trata de identificar el por que tenemos un exceso de los integrantes del poder legislativo del estado de Campeche, comparados con 31 congresos locales que existen en el pais, ademÃ¡s que propone una reforma que permita disminuir a los integrantes del poder legislativo , apegÃ¡ndonos en lo mÃ¡s estricto a la media nacional de personas que debe representar un legislador local, asimismo realiza un comparativo de los congresos locales con los Estados que comparten fronteras territoriales.
OSSICULOPLASTY: AUTOGRAFT VS ALLOGRAFT
Authors: Solanki Karnadev , Chavda Navdeep , Doshi Hiren
Published: January 2023

Background: Chronic otitis media (COM) is defined as a perforation of the tympanic membrane with persistent drainage of pus from the middle ear lasting at least two weeks. Tympanoplasty is a surgical procedure in ENT practice which aims at removal of diseased pathology from middle ear along with reconstruction of sound conducting mechanism by reconstructing the ossicular chain with various materials. Methods:All the cases of CSOM with ossicular chain deformity were included. Ear examination was done in detail, Preoperative hearing assessment was done and Hearing loss was calculated by average air bone gap on PTA.For Auto graftstragal cartilage or incus was used andfor allograft Teflon TORP/PORP with cartilage cap was used. Results: Comparison forossiculoplasty was done by comparing its advantages and disadvantages in the terms of extrusion rate and hearing restoration in postoperative period. Overall failure rate for autologous material was 8% and for alloplastic material was 12%. Conclusion: the use of autologous graft is more advantageous in terms of surgical outcome, extrusion rate, and postoperative hearing gain.
SLEEP BEHAVIORS THAT AFFECT THE DEVELOPMENT OF MENTAL HEALTH CONDITIONS
Authors:   Beaconhouse Yamsaard Huahin School, Thailand., Khosabordee Palida , Chattaweewut Wityada ,   International School of Samui, Thailand., Vijitpornkul Kajornyos ,   Triamudom Suksa School, Thailand., Inkheaw Wisanlaya ,   Satriwithaya School, Thailand.
Published: January 2023

Most of the respondents are female, aged 17â€“22 years, they are students/college students and are single. From the study, it was found that most of the samples had sleeping behavior. In terms of the sleeping duration which is between 5-8 hours, followed by less than 5 hours and more than 8 hours, respectively. In terms of the sleeping time, most of them had during 22.01-00.00, followed by 00.01-02.00, after 02.00 and 20.00 - 22.00, respectively. As for the study of symptoms and mental state, it was found that it was at a moderate level. When considering one by one, it was found that the symptoms of irritability and mood swings were the most, which were at a moderate level, followed by the anxiety of people being around them and their surroundings, feeling depressed and unhappy in life, respectively which is at a low level of symptoms. Therefore, from the results of the study, it can be concluded that sleep behavior affects the incidence of mental health conditions because most of the samples had a sleep duration in the normal period of 5-8 hours, and most of them slept during a reasonable time, not too late, which is during 22.01-00.00 hrs. This causes the overall symptoms to be at a moderate level. However, there are some behaviors of staying up late and sleeping less which may affect the risk of various mental health conditions in the future.
CRECIMIENTO ECONOMICO (ODS 8) A TRAVES DE LA IMPLEMENTACION DEL MODELO SERVQUAL EN UN HOTEL DEL SURESTE DE MEXICO
Authors:   PhD in Administration Sciences, Academic Researcher, Faculty of Administration and Finance, Autonomous University of Campeche., Monserrat Llanes Chiquini Charlotte , David Soto Barrera Victor ,   Masters Degree in Administrative Innovation at the Autonomous University of Campeche - Faculty of Accounting and Administration., Alberto Perez Canul Carlos ,   PhD in Administration Sciences, Academic Researcher, Faculty of Administration and Finance, Autonomous University of Campeche., Gerardo Trejo Llanes Rafael ,   Masters in Administrative Engineering, Academic Researcher, Inter-American University for Development (UNID)Campechecampus., Manuel Patron Cortes Roger ,   PhD in Administrative Management, Academic Researcher, Faculty of Administration and Finance, Autonomous University of Campeche., Isabel Perez Aranda Gabriela ,   PhD in Humanist Education. Academic Researcher, Faculty of Humanities, Autonomous University of Campeche., Ashanty De Las Maravillas Del Valle Zetina Isis ,   Masters Degree in Criminal Law Sciences, Academic Researcher Technological of Campeche.
Published: January 2023

Mantener el crecimiento economico per capita de conformidad con las circunstancias nacionales y, en particular, un crecimiento del producto interno bruto de al menos el 7% anual en los paÃ­ses menos adelantados es uno de los propositos del objetivo de desarrollo sostenible nÃºmero 8 de la Organizacion de las Naciones Unidas (ONU), Trabajo decente y crecimiento economico por lo que, cualquier iniciativa de las empresas particulares para lograr dicho objetivo es de gran valÃ­a para la economÃ­a del paÃ­s. Muestra de esto, son los esfuerzos que estÃ¡ realizando la empresa hotelera quedÃ¡ origen a esta investigacion a traves de un sistema de calidad el cual debe conducir a la satisfaccioÌn de los requisitos del cliente, tanto internos como externos, teniendo un desempenÌƒo eficaz en los procesos de la organizacion, por lo tanto, un hotel debe considerarse como un sistema, donde se debe optimizar todos los servicios proporcionados con la calidad que el cliente espera para que cubra sus expectativas. Esta investigacion plantea la implementacion del Modelo Servqual en un hotel de cuatro estrellas en la ciudad de San Francisco de Campeche, Campeche, Mexico, con la finalidad de establecer un plan de accion para mejorar la calidad en el servicio dentro de los procesos de la organizacion y por ende mantenerlo en funcionamiento competitivo.
RADIOLOGICAL MANAGEMENT OF SPLENIC ARTERY INJURY FOLLOWING ROUTINE COLONOSCOPY
Authors: Patel Sima , Carioni Blanca , Pereira Gordon
Published: January 2023

Colonoscopies can be used for both interventional and dialogistic purposes. The use of colonoscopies is not without risk and an awareness of these risks, as well as the clinical presentation of these risks / adverse effects, is vital to ensure optimal patient care is achieved both throughout and after the procedure. We present a case of a 49-year-old patient who presented to a district general hospital within the National Health Service (NHS) with diffuse abdominal pain and haemodynamic instability following a colonoscopy. A splenic artery injury was identified following a computerized tomography (CT) scan with contrast, of the abdomen and pelvis of the patient. The patient was resuscitated and managed without the need of surgical intervention in the form of targeted splenic artery embolization. This case highlights that a high index of suspicion of splenic injury should be held by the clinical in any patient who presents with abdominal pain with or without haemodynamic instability as early intervention is key to good patient outcomes.
THE USE OF GOOGLE WORKSPACE TOOLS IN HIGHER EDUCATION DURING THE PANDEMIC LEARNING IN HIGHER EDUCATION DURING THE PANDEMIC
Authors: Sena Marques Gabriel , Victor Reis Bezerra Da Silva Joao , Mark Lobo De Oliveira Jean
Published: January 2023

In thispaper, we are goingtobrieflydiscussaboutGoogle Workspacesrolein highereducationduringthepandemic,whatweretheadvantagesthatthis tool offeredto help people,whatwerethemostusedpre-existingmethodsapplied as anaidtoeducationduringthispandemicandhow it affectedpeoplewhochangedtheirstudyroutinetoadapttousingthis tool.
AN INSTITUTIONAL STUDY ON COVID-19 ASSOCIATED RHINO-ORBITAL-CEREBRAL MUCORMYCOSIS
Authors:   Final Year Resident, Department of ENT, Gadag Institute of Medical Sciences, Gadag, Karnataka, India., S. Reshma , Ingale Arun ,   Assistant Professor, Department of ENT, Gadag Institute of Medical Sciences, Gadag, Karnataka, India., Kuradagi Vinayak ,   Senior Resident, Department of ENT, Gadag Institute of Medical Sciences, Gadag, Karnataka, India., Babu K. Sharath ,   Professor & HOD, Department of ENT, Gadag Institute of Medical Sciences, Gadag, Karnataka, India.
Published: January 2023

Background: Prior to the COVID-19 pandemic, the prevalence of mucormycosis in India was approximately 0.14 cases per 1000 population. With the second wave of the COVID-19 pandemic, there has been a tremendous increase in the number of Rhino-Orbital mucormycosis cases with a high mortality of 30.7%.This paper discusses the institutional experience of 67 cases of rhinoâ€“orbitalâ€“cerebral mucormycosis related to COVID-19 infection. Methods: In this case series, 67 proven cases of COVID-19 associated rhino-orbital-cerebral mucormycosis were analyzed retrospectively from April 2021 to March 2022. Clinical profile of all the patients were studied for signs and symptoms at presentation, possible risk factors and comorbidities. Microbiological and imaging studies was done in all patients and taken up for surgical management which included open or endoscopic debridement, maxillectomy, orbital decompression, orbital exenteration etc. Postoperatively patients were started on parenteral antifungal and discharged on oral antifungal after repeat imaging and endoscopy to rule out residual or recurrent disease. Results: The mean age of presentation was 49.1 years. Diabetes and use of steroids during covid treatment was seen in 91% and 83.5% of cases respectively. Unilateral headache and nasal obstruction were the most common symptoms. Open debridement using Weber Ferguson incision and medial maxillectomy was the most common surgical approach followed in our institution with good recovery and less chances of need for revision surgery. Conclusion: Timely diagnosis and intervention in the form of thorough surgical debridement and antifungal therapy are critical aspects in improving clinical outcomes in such patients.
A STUDY ON PREDICTION OF ALLERGIC FUNGAL RHINOSINUSITIS WITH SERUM IGE LEVELS
Authors:   Final Year Resident, Department of ENT, Gadag Institute of Medical Sciences, Gadag, Karnataka, India., S. Reshma , Ingale Arun ,   Assistant Professor, Department of ENT, Gadag Institute of Medical Sciences, Gadag, Karnataka, India., Kuradagi Vinayak ,   Senior Resident, Department of ENT, Gadag Institute of Medical Sciences, Gadag, Karnataka, India., Babu K. Sharath ,   Professor & HOD, Department of ENT, Gadag Institute of Medical Sciences, Gadag, Karnataka, India.
Published: January 2023

Background: Allergic fungal rhinosinusitis (AFRS) with IgE mediated allergic pathogenesis is a category of non-invasive fungal sinusitis. In our study, we followed up patients with AFRS who have undergone functional endoscopic sinus surgery and correlated endoscopic appearance (Kupferberg staging) with pre and postoperative total serum IgE levels. Objectives: 1. To assess preoperative and postoperative endoscopic staging as well as total serum IgE levels in patients with AFRS who underwent functional sinus surgery. 2. To assess the sensitivity of total serum IgE level in predicting the disease status in patients with AFRS on postoperative follow up. Methodology: Aprospective longitudinal cohort study was done on 68 patients diagnosedtohave AFRS. Preoperative endoscopic staging was done along with total serum IgE levels and skin allergy test for all patients. Postoperatively the patients underwent repeat endoscopy and serum IgE level testing at 4 to 7 months follow up. Results: We had 68 patients in the age group of 21-60 years in the study. The majority of the patients in the study group were males (61.8%). In our study, 54 of 68 patients had a fall in postoperative total serum IgE levels when compared to their preoperative values. The sensitivity of total serum IgE levels in this study was, therefore, 84%. The specificity of total serum IgE level was only 33.3% in our study. Conclusion: In this study on patients with AFRS who underwent total serum IgE estimation and rigid nasal endoscopy both pre and post operatively shows that total serum IgE levels is a fairly good prognostic measure in patients with AFRS. Eventhough the test specificity is low, both total serum IgE levels and clinical findings together may be ideal to asses the prognosis for the individual patients with AFRS.
A CASE OF HODGKIN LYMPHOMA PRESENTING AS NEPHROTIC SYNDROME
Authors:   Professor., Satya Prasad M.D. V. , Vana (M.D.) Pranaya ,   Post Graduate., Harshitha (M.D.) Vaddi ,   Post Graduate., Karnatapu (M.D.) Vaishnavi ,   Post Graduate.
Published: January 2023

Paraneoplastic glomerulopathy has been reported in patients with malignancy.In particular, the association of Nephrotic Syndrome (NS) with Hodgkins Lymphoma (HL) is rare and there are few reports in the literature. Minimal change nephropathy is the most frequently observed renal lesion whereas this association appears, either simultaneously or within several months of each other. Nephrotic changes as part of the paraneoplastic syndrome are rare in lymphoid malignancies. 1% of cases of Hodgkins Lymphoma cases may present with nephrotic syndrome. We are reporting a case which initially presented as nephrotic syndrome and later was diagnosed to have of Hodgkins Lymphoma and managed accordingly. This report presents the case of a 13-year-old male in whom the diagnosis of NS was established six months before the diagnosis of Hodgkin lymphoma. Once chemotherapy was initiated, proteinuria and the clinical manifestations of NS, mainly oedema, disappeared. Considering that the NS can be a paraneoplastic manifestation of Hodgkin lymphoma, the careful clinical evaluation becomes mandatory in any child with NS and persistent proteinuria despite appropriate treatment protocol. The prognosis of these patients is good, the treatment of Hodgkin disease causing the disappearance of proteinuria.
PREVALENCE AND CAUSES OF RECURRENT PEPTIC ULCER
Authors:   Family Medicine Consultant at Fakeeh Collage for Medical Sciences (FCMS), Jeddah, KSA., Abdulrahman Hafiz Lubna , Abdul Rahman Hafiz Halah ,   Assistant Professor, Umm Alqura University, Makkah, KSA., Hassan Althuwaybi Yazeed ,   Service Doctor, MD, KSA., Mohammed Alamri Abdulmalik ,   Service Doctor, MD, KSA., Aidarous Alaidarous Fatimah ,   Service Doctor, MD, KSA., Hail Alanizy Bandar ,   Service Doctor, MD, KSA., Gazaa Al Rashedi Ahmad ,   Service Doctor, MD, KSA., Faiq Alsarraj Nawaf ,   Service Doctor, MD, KSA., Ali Al Ahmar Salma ,   Service Doctor, MD, KSA., Bahar Shibli Mohammed ,   Service Doctor, MD, KSA., Ibrahim Atiah Abdulrahman ,   Medical intern, MBBS, KSA., Mohammed Alshammari Abdulaziz ,   Medical intern, MBBS, KSA., Madloul Aldhafeeri Fawaz ,   Medical intern, MBBS, KSA., Nasser Alajmi Naif ,   Medical intern, MBBS, KSA., Yahya Habiby Ayob ,   Medical intern, MBBS, KSA.
Published: January 2023

Background:Peptic ulcer disease (PUD) is a common disease of the gastrointestinal tract characterized by mucosal damage due to the secretion of pepsin and gastric acid. The current study aimed to determine the prevalence and causes of recurrent peptic ulcer. Methods:The current study adopted an exploratory study design in order to determine the prevalence and causes for recurrent peptic ulcer disease in individuals and predict an outcome. The participants for the current study were individuals belonging to the age group 18-75. This age group is chosen as the major influence of peptic ulcer disease is observed within this group.For the current study, questionnaire was adopted for data collection, which was also categorized as a study tool. Results:Study included 589 participants. It is noticed that most of participants (n= 530, 90.1%) strongly agree that they visit the doctor periodically to check on their health. Previous item has the highest rank followed by participants follow smoking lifestyle (n= 526, 89.4%). On the other hand, the least rank item on which participants strongly disagreed was participants suffered from soreness or bleeding from their stomach (n= 249, 42.4%). This gives a prevalence of 42.4% of peptic ulcer disease among study participants. Conclusion:Peptic ulcer illness burdens health care systems, which urge for adequate treatment to limit recurrence and effects. H. pylori, smoking, and aspirin usage are risk factors for 5-year peptic ulcer recurrence. Long-term PUD hazards include smoking and aspirin. Avoiding risk factors reduced the recurrence rate of H. pylori eradication, acid suppression medication, and surgery. This shows how eliminating risk factors may enhance long-term performance. Proper PUD treatment requires multicenter research to prevent recurrence and repercussions.
PARENTS COMMITMENT TO THE CHILDS VACCINATION ACCORDING TO AGE SCHEDULE: A SYSTEMATIC REVIEW
Authors:   Assistant Professor & Consultant of Pediatric, Department of Pediatrics, King Abdulaziz Medical City, Jeddah, KSA., Abdullah Attia Najya , Jehad Abousada Hoda ,   Obstetric&Gynecology, Master SA, KAMC, Jeddah, KSA., Mohammadfowzi Marghlani Faris ,   Service Doctor, MD, KSA., Ahmed Ghunaim Abdullah ,   Service Doctor, MD, KSA., Abdulghani Taj Mashael ,   Service Doctor, MD, KSA., Kissnawi Umkalthommahmoud ,   Service Doctor, MD, KSA., Abdullah Alzahrani Khalid ,   Service Doctor, MD, KSA., A. Almutairi Faisal ,   Service Doctor, MD, KSA., Mohammed Alzahrani Omar ,   Service Doctor, MD, KSA., Mohammed Alhamyani Naif ,   Service Doctor, MD, KSA., Manaa Adeebbassam ,   Medical Intern, MBBS, KSA., Awadh Alamri Feras ,   Medical Intern, MBBS, KSA., Bandar Albalawi RN: Norah ,   Nursing Specialist, KKH, KSA.
Published: January 2023

Vaccine uptake may be predicted in large part by whether or not vaccinations are accepted. This has ramifications for public health since unvaccinated people are more likely to get illnesses that vaccines can prevent. Our purpose in conducting this systematic literature review was to analyse parents commitment to the childs vaccination schedule.We conducted a comprehensive literature search for studies published between January 2012 and present that used instruments to gauge vaccine-related attitudes and convictions. Included studies surveyed parents quantitatively to determine their opinions on paediatric immunizations. We compiled the data with an emphasis on how well the various methods of measuring hesitation performed. A total of 16 studies were included because they satisfied the inclusion criteria 13 of these used a cross-sectional research design, 2 used a case-control study design, 1 used a pre-post study design. There was a wide variance in study sample sizes from 49 to 12,259. The PACV Survey of Parents Opinions on Childrens Vaccines was the instrument most often used. The Health Belief Model was the most popular theoretical framework. There was a broad range of questions designed to elicit opinions on vaccinations.The studies that polled parents about their thoughts on immunization utilized a wide variety of questionnaires. Validated and standardized but adaptable tools might enhance methods for measuring parents perspectives on immunization. It is recommended that researchers in this field use a standardized set of questions.
SYSTEMATIC REVIEW OF THE PREVALENCE OF ANXIETY AND DEPRESSION DISORDERS AMONG PATIENTS WITH INFLAMMATORY BOWEL DISEASE
Authors:   Associate Professor of Family Medicine, Department of family & Community Medicine, Faculty of Medicine, King Abdulaziz University, Rabigh., Abdulaziz Murad Manal , Hussain Alasmri Ahmed ,   Medical Resident R4, Armed Forces Hospital Southern Region (Afhsr), Khamis Mushiat, KSA., Jehad Abousada Hoda ,   Obstetric& Gynecology, Master SA, KAMC, Jeddah, KSA., Ismailmoosa Hassan Aminah ,   Service Doctor, MD, KSA., Mohammed Alamri Saeed ,   Service Doctor, MD, KSA., Ali Alharthi Mohammed ,   Service Doctor, MD, KSA., Almatrafi Bananmasoud ,   Service Doctor, MD, KSA., Masoud Almatrafi Bayan ,   Service Doctor, MD, KSA., Kamil Tamim Bakur ,   Service Doctor, MD, KSA., Ibrahim Mirdad Abdullah ,   Service Doctor, MD, KSA., Ibrahim Ali Maram ,   Medical Intern, MBBS, KSA., Albushra Mesharimuslih ,   Medical Intern, MBBS, KSA., Ahmed Alzahrani Torki ,   Medical Intern, MBBS, KSA., Mohammad Homadi Nuran ,   Clinical Pharmacist, KSA., Maysha Alotaibi RN: Ghazi ,   Specialist Nursing, KSA.
Published: January 2023

Background: Mental health is an important but often disregarded part of inflammatory bowel disease (IBD) patient care, with difficulties defining effective medications and psychological health services. Anxiety and sadness are the most frequent psychosocial problems among IBD patients. The rising frequency of these mental problems calls for mental screening of all IBD patients at the initial appointment. Objective: A growing number of research on anxiety and depression in IBD have been undertaken nevertheless, there is no clear consensus on the prevalence of anxiety and depression in this group. The goal of this systematic review was to consolidate current data on the prevalence of depression and anxiety disorders in individuals with IBD. Methods: Authors began with recognizing the important examination proof that spots light on the prevalence of anxiety and depression among IBD patients. We led electronic writing look in the accompanying data sets: Ovid Medline (2010 to present), Ovid Medline Daily Update, Ovid Medline in process and other non-filed references, Ovid Embase (2010 to present), The Cochrane Library (latest issue) and Web of Science. Just examinations in English language will be incorporated. The precise selection was acted in close collaboration with a clinical examination curator. Results: There were 10 articles found, with a total of 26097 participants. The pooled prevalence estimate for anxiety disorders was 20.3%, and 13.3% for depression. When compared to those in remission, IBD patients in active illness showed a 75.6% greater prevalence of anxiety. Depressive symptoms were more common in Crohns disease than in UC (P0.001), and more common in active illness than in IBD patients in remission (P= 0.004). Conclusion: Results from this systematic review indicate that patients with IBD have about a 20.3% prevalence rate of anxiety and a 13.3% prevalence rate of depression.
DIAGNOSIS AND MANAGEMENT OF KATIGATAVATA (LOW BACK PAIN) IN AYURVEDA: A CRITICAL REVIEW
Authors:   Consultant, Department of Shalya Tantra, Nootan AyurvedicCollage and Research centre ( Proposed ), Sankalchand Patel University, Visnagar, Mahesana., Nath Chouhan Poona
Published: January 2023

Introduction: Low back pain has prevalence of 6.2% in general population to 92% in construction workers in India. Current health system is not so much updated to rule out this entity early which tend to cause much more devasting medical conditions and economical expenses. This outcome generates an opportunity for Ayurveda to manage it with conservative treatment. Aims and objectives: To Compile the reference of KatisandhigataVata (Definition, Nidana, Lakshana and Chikitsa) mentioned in various classical texts and to evaluate the treatment modalities useful for the management. Discussion: Sandhi is a union of Asthi which is Ashrya of VataDosh so as its vitiation progress, its RuksaGuna also increases which lead to Dhatukshaya and Snehanash reduction. So Asthi and Sandhi related Vikaras also show progression. All the classics mentioned the use of Snehana and UpanahaKarma which will control RuksaGuna of Vatadosha. Result: Remedies mentioned in Ayurveda classics may boost up the options to manage it with less efforts, maximum benefits, and least side effects.
A CASE SERIES OF 5 RARE ABDOMINAL EMERGENCIES
Authors:   Department of General Surgery, MGM Medical College, Navi Mumbai, MGM Institute of Health Sciences., Devdikar Shrutik , A. Kalokhe Shifa ,   Department of General Surgery, MGM Medical College, Navi Mumbai, MGM Institute of Health Sciences., Suraj Lisha ,   Department of General Surgery, MGM Medical College, Navi Mumbai, MGM Institute of Health Sciences.
Published: January 2023

Gastrointestinal perforation is a common cause of acute abdomen due to peritonitis. The etiology and pathophysiology of gastrointestinal perforations is varied and can range from a small prepyloric perforation that is relatively clean to transection of small or large bowel with spillage of contents in peritoneum with gross contamination. Some of these are more common than others. Here we present 6 cases of rare perforations presenting to us in the casualty, their management and postoperative course in hospital. Methods: We will be assessing the cases of patients, their history, clinical presentation, radiological imaging who presented with acute abdomen secondary to bowel perforation and were intraoperatively diagnosed to have a rare pathology and assess the management and postoperative outcomes. Results: In this case series, 5 rare cases of GI perforations are highlighted including rare cases of posterior gastric perforation, DJ transection, jejunal transection, jejunal perforation, large mesenteric tear and sigmoid colon perforation. All these cases required a different approach in managing intraoperatively. Conclusion: Gastrointestinal perforation is a common cause of acute abdomen and requires emergency surgical intervention. CT imaging has become a fundamental part of the preoperative evaluation and can determine site and cause of perforation.Gastrointestinal tract perforations can occur due to various causes, and most of these perforations are emergency conditions that require early recognition and timely surgical treatment the mainstay of treatment for bowel perforation is surgery. Atypical presentation of perforation can be a challenge to surgeons andshould be prepared to deal with it.
AWARENESS ON BIOMEDICAL WASTE MANAGEMENT AMONG DENTAL STUDENTS -A CROSS SECTIONAL QUESTIONNAIRE SURVEY
Authors:   Undergraduate Student, Care Dental College and Hospital, Guntur, Andhra Pradesh., Reshma Shaik , Arshiya Shaik ,   Undergraduate Student, Care Dental College and Hospital, Guntur, Andhra Pradesh., Prabhath K. Eswar ,   Undergraduate Student, Care Dental College and Hospital, Guntur, Andhra Pradesh., Raja Sekhar Potluri ,   Assistant Professor, Department of Public Health Dentistry, Care Dental College and Hospital, Pothur, Guntur., Ranganath Sanga ,   Professor and Head, Department of Public Health Dentistry, Care Dental College and Hospital, Pothur, Guntur.
Published: January 2023

Introduction: It is known that many countries worldwide have been facing a common problem hazardous to both health and environment of their civilizations is health care waste. Healthcare services involved in serving people has been producing indiscriminate amount of these biomedical waste, which is not a neglecting fact as linked to our current state of the earth which is already facing many risks and disasters in the form of pollution, changes in biodiversity and climatic conditions of it inhabitants . Objective: With this background in picture, present study was conducted with an objective to assess awareness on biomedical waste management through a knowledge, attitude, and practice questionnaire survey among dental undergraduate students and house surgeons. Materials and Methods: A cross-sectional questionnaire survey was conducted among the study population in an institution located in Southern part of Andhra Pradesh state. A total of 120 study subjects participated in the survey with earlier consent. Statistical Analysis: Collected data were tabulated, and interpreted in percentages of observations by using SPSS software version 20.0 Results: From the study, it isrevealed that the knowledge and awareness regarding BMW management was satisfactory among the third year dental students and house surgeons with few lapses observed in the overall training of the students regarding BWM. Conclusion: The result clearly shows the need for a complete and constant educational programme regarding various medical hazards associated with improper waste management at all levels of the dental curriculum.
A Study on Emotional Evaluation and Perception of Sotdae-pattern of Teaware
Authors:   Association for International Tea Culture, Kim Sook-kyoung , Choi Bae-young
Published: January 2023

The objective of this research is to present the base data for development of teawares with Sotdae-patterns by studying the emotion and perception of expert group and consumer group. For this study, teawares with individually drawn five types of Sotdae-pattern were made in October 1-31, 2022. These teawares were photographed and each pattern was included in the survey. A total of 24 experts and 26 consumers were surveyed, who use teawares more than once a week. The survey was conducted in November 1-7, 2022. and the survey data were analyzed by SPSS 29.0. The main results are as follows. First, the five Sotdae-patterns were generally highly evaluated with Korean emotion. In addition, patterns of Bukhansan mountain-Sotdae and Ojuk(black bamboo)-Sotdae showed natural and artistic sensibility, whereas, patterns of Sky-Sotdae, Earth-Sotdae and Community-Sotdae were assessed with inventive and individual emotion. Second, the purchase intention of teawares was high in the order of Ojuk-Sotdae pattern > Bukhansan mountain-Sotdae pattern > Sky-Sotdae pattern > Community-Sotdae pattern > Earth-Sotdae pattern. Third, using the Sotdae-pattern teawares reflected introspection with psychological stability and relaxed mind, and expectation of communication in a comfortable mood with someone while drinking tea.
A Study on Activation Plan of Education Program in Tea Museum: Focused on Hoann Museum of Tea Ware
Authors:   Association for International Tea Culture, Yun Byung Hwa
Published: January 2023

The Hoann Museum of Tea Ware is a culture and art complex of tea culture that has provided appreciation of works related with tea and education programs including traditional etiquette, tea ceremony(茶禮) and practice of tea manufacture since its opening on December 15th of 2007 by remodeling the closed school. The Hoann Museum of Tea Ware is optimally qualified for a open culture and art complex to learn culture and art and traditional etiquette. Especially, it creates an environment for appreciation and research of antiques and discussing a history and culture of tea for students studying a tea master and tea and people interested in pottery. This study researched and analyzed the programs including experience of Deokeum Flower Tea, tea ceremony and tea confectionery from ‘Humanities on the Road’ program in the Hoann Museum of Tea Ware, and suggested the plan to design experience programs of five senses in preparation for the post-COVID 19 era. It specifically diversifies participants and consolidates online education, securing experience and public concern.
Primary immunodeficiency in a patient with Kabuki syndrome
Authors: Dolgopolov I. S. , Grivtsova L. Yu. , Ustinova O. K. , Rykov M. Yu.
Published: January 2023

Kabuki syndrome is a well-known disease characterized by postnatal growth failure, dysmorphic facial features, skeletal abnormalities, and mental retardation associated with one of the pathogenic mutations in the KMT2D or KDM6A genes. At least 50% of individuals with Kabuki syndrome tend to develop recurrent infections and immune abnormalities, primarily hypogammaglobulinemia. The article describes the clinical course of resistant infectious syndrome in an 18-month-old child without typical dysmorphic and dermatoglyphic manifestations characteristic of Kabuki syndrome. A long history of resistant bacterial infection, enterocolitis, microcephaly, autistic-like behavior, hyperkinetic disorder, CT scan patterns of granulomatous lymphocytic interstitial lung disease (GLILD), suggested the immunodeficiency as part of a hereditary genetically determined syndrome. At the same time, the patient did not experience hypogammaglobulinemia characteristic of Kabuki syndrome. The upper normal response to previously received vaccination and a polyclonal repertoire of B-lymphocytes indicated the absence of disturbances in the humoral immunity. Immunophenotyping revealed the absence of T-regulatory cells (CD4+CD25++CD127–) as well as effector NK cells (CD16+CD56+CD3–) in the peripheral blood. The significant reduction of CD4+CD3+ T-lymphocytes and CD4+/CD8+ index was observed. In addition, no expression of integrin-beta (CD18) on neutrophils revealed.Conclusion. In children under the age of 2, Kabuki syndrome may present difficulties for clinical diagnosis due to the absence of distinctive phenotypic signs. Patients with mental disorders, congenital malformations, recurrent infections suspected of immunodeficiency should be carried out using molecular genetic exploration, including testing for mutations in the KMT2D and KDM6A.
Difficulties in the differential diagnosis of Angelman’s syndrome
Authors: Gorchkhanova Z. K. , Nikolaeva E. A. , Pivovarova A. M. , Bochenkov S. V. , Belousova E. D.
Published: January 2023

Angelman syndrome is a rare neurogenetic disease caused by the loss of the function of the maternal allele of the UBE3A gene on chromosome 15 (site 15q11.2–q13) and is characterized by severe mental retardation, lack of speech, epilepsy, microcephaly and a characteristic facial phenotype with a unique behavior in the form of frequent laughter. The combination of microcephaly, epilepsy, speechlessness and mental retardation poses a problem for differential diagnosis with many genetic diseases presenting with similar symptoms. Epileptic encephalopathy due to CDKL5 gene mutation and Rett syndrome have the greatest similarity. The hallmark of Angelman syndrome are laughter attacks and specific EEG changes. The authors have presented a table of the differential diagnosis of Angelman syndrome with some phenotypically similar genetic syndromes, indicating the most significant distinguishing features, which should facilitate for the pediatrician and neurologist the diagnostic path of establishing the correct diagnosis.
Impact of prenatal diagnosis on outcomes of surgical correction in newborns with transposition of the great arteries comparing to other critical congenital heart defects
Authors: Gorbunov D. V. , Abikeyeva L. S. , Zhumabayeva M. M.
Published: January 2023

A review of the literature data describing the influence of prenatal diagnosis of critical congenital heart defects on perioperative and long-term results is presented, with a focus on the features of prenatal detection of transposition of the great arteries. This heart defect is a convenient object of studying due to the relative anatomical homogeneity of the nosological form; the birth of patients, as a rule, at full term; the rarity of the combination of this pathology with multiple congenital malformations and chromosomal abnormalities that can potentially worsen the results of treatment; the similarity of the principles of preoperative management in this category of patients in different clinics; the performing of arterial switch surgery in a strictly defined time frame (usually during the first month of life); the relative similarity of surgical techniques used. The relevance of this study is to identify patterns that make it possible to improve existing protocols for the treatment of newborns with transposition of the great arteries and create new algorithms for interaction between gynecologists, neonatologists, resuscitators, and cardiac surgeons.
Hyperlipidemia in children: Unsolved problems
Authors: Nikitina M. I. , Santalova G. V.
Published: January 2023

The article presents literature review findings on the prevalence, diagnosis, and treatment of hyperlipidemia, including familial hypercholesterolemia in children. It is noted that the number of patients with hyperlipidemia continues to grow throughout the world. As before, hyperlipidemias are considered risk factors for the development of cardiovascular diseases and the cause of high mortality in different countries of the world. Attention is drawn to the possibility of atherosclerotic lesions of the heart vessels in young people and adolescents. Diseases in children (diabetes mellitus, obesity, hypothyroidism, renal pathology, etc.) have been noted, which necessitate diagnosing hyperlipidemia. There are no clear guidelines for pediatricians regarding cholesterol screening and timing of therapy initiation.
Hemogram indicators in children aged 7–14 years with new coronavirus infection
Authors: Bogomolova I. K. , Babkin A. A. , Peregoedova V. N.
Published: January 2023

The research is focused on the evaluation of a general blood test in children with a new coronavirus infection, depending on the severity of the disease. 107 patients with virus-identified new coronavirus infection aged 7–14 years were examined. 19 (17.8%) were diagnosed with asymptomatic, 69 (64.4%) mild, and 19 (17.8%) moderate COVID-19. The control group is represented by 75 healthy children. The hemogram indicators in each group were analyzed, a correlation analysis of the red and white blood cell counts with the severity of the disease was carried out. In children with a new coronavirus infection, a significant decrease in the blood hemoglobin relative to the control group was revealed, although not exceeding the normal values. An inverse correlation was established between a decrease in the WBC and absolute lymphocytes count and the severity of clinical manifestations of the disease.
Comorbid pathology in children with type II–III spinal muscular atrophy on the background of acquired deformities of the skeleton bones
Authors: Evreinov V. V. , Raznoglyadova E. A.
Published: January 2023

Spinal muscular atrophy (SMA) is a severe genetic disease associated with impaired SMN protein synthesis and degeneration of alpha motor neurons in the spinal cord. Developing neurogenic kyphoscoliosis and deformity of the chest against the background of symmetrical muscular hypotension sharply limit the activity of patients, worsening the concomitant diseases.Purpose. The study aims at determining the comorbid background of children with type II–III spinal muscular atrophy who underwent inpatient treatment for acquired skeletal bone deformities.Material and methods. A retrospective analysis of the data was carried out for the period from 2017 to 2021 based on the medical records of 31 children. The study group included 10 girls and 21 boys; 16 children were with type II and 15 — with type III spinal muscular atrophy. The following were assessed: comorbidity, neurological status, hemodynamic parameters, echocardiography, spirometry, laboratory research data.Results. In our study, comorbidity was associated with nutritional status (19% of patients overweight, 29% underweight), mental retardation (3%), gastroesophageal reflux disease (19%), diseases of the ENT organs (16%), eyes (19%), heart and lungs (93%). For health reasons, 61% of children required the use of non-invasive ventilation, and 71% of insufflator-aspirators. Limited motor abilities were registered based on the HFMSE and GMFCS scales, dysphagia based on the EDACS scale. A biochemical blood test revealed a low level of creatinine.Conclusion. Patients with spinal muscular atrophy require multidisciplinary care in diagnosis, treatment and rehabilitation. The use of objective rating scales, instrumental and laboratory methods of examination allow for a comprehensive analysis of the potential of children with spinal muscular atrophy, to select effective, family-oriented treatment regimens. Serum creatinine as a biomarker for the severity of muscle denervation makes it possible to monitor the progression of spinal muscular atrophy and predict response to treatment.
About the constitutional features of gastric and duodenal ulcer in children
Authors: Kharitonov D. V. , Sapozhnikov V. G. , Kharitonova L. A.
Published: January 2023

Peptic ulcer disease is a fairly rare pathology of childhood. Therefore, it is important to analyze some features of peptic ulcer of the stomach and duodenum in children, depending on the body type.Purpose. To analyze some features of peptic ulcer of the stomach and duodenum in children, depending on the body type.Material and methods. We examined 58 children aged 12–18 years with a diagnosis of peptic ulcer of the stomach and/or duodenum, who underwent endoscopic examination, H. pylori was detected in the biopsy and aero test.Results. Peptic ulcer disease was more often detected in asthenic children (67.2%), less often in hypersthenic (17.3%) and normosthenics (15.5%). Various research methods in asthenic children (97.4%) revealed the presence of H. pylori more often than in hyperor normosthenic children.Conclusion. Children with an asthenic type of constitution are more prone to Hp-associated forms of gastric and duodenal ulcers than hypersthenics or normosthenics.
Premature children and assessment of their capability for school education by 7 years of age (the role of interdisciplinary approach
Authors: Keshishyan E. S. , Ziborova M. I. , Sakharova E. S.
Published: January 2023

In recent decades, there has been a distinct increase in the number of deeply and extremely preterm children without structural organic lesions of the nervous system. A comprehensive study and clinical observations of these children reveal their differences from full-term peers, becoming the most obvious by the beginning of schooling. In this article, we consider the cognitive, behavioral, and socializing features of these children, paying attention to key biosocial factors of their development, such as the long-term influence of the early neonatal period on the formation of brain structures and connections and the «resetting» of the neurohumoral system, the role of genomic polymorphism, the special importance of a favorable environment for the emotional well-being and success of these children among their peers. Knowledge and understanding of extremely preterm infants’ specific development, typical risks of behavioral disorders and social disfavor is of great practical importance for prolonged interdisciplinary follow-up — in the form of appropriate medical, educational, and psychological programs.
Quality of life in children with atopic dermatitis aged 13–17 years
Authors: Vostrikova S. A. , Penkina N. I. , Ivanova M. A.
Published: January 2023

Purpose. To study the quality of life of children aged 13–17 years with atopic dermatitis, depending on the sex of the child, the severity of the disease.Material and methods. 350 children aged 13–17 with atopic dermatitis (observation group) and 350 children of the same age of I– II health groups, without allergic diseases (comparison group) were examined. The quality of life of children and their parents was studied using a general questionnaire, Pediatric Quality of Life Inventory — PedsQL™4.0 (Varni J. et al., USA, 2001).Results. The quality of life of children with atopic dermatitis aged 13–17 years is reduced in all respects in comparison with their healthy peers. Atopic dermatitis had the greatest negative impact on such areas of the child’s life as emotional, school, and social functioning. The quality of life in children aged 13–17 years with severe cases of atopic dermatitis was significantly more impaired in girls, compared with boys. Parents rated the quality of life of their children higher than the children themselves.Conclusion. A significant decrease in emotional, school, and social functioning in the structure of the components of the quality of life of children aged 13–17 years with atopic dermatitis indicates the need for timely diagnosis of these disorders and their correction.
Rare variant of heterotaxy syndrome in childhood in pulmonology clinic
Authors: Mizernitskiy Yu. L. , Novak A. A. , Zorina I. E. , Ryabova S. E. , Kovalev I. A. , Verchenko E. G. , Bereznitskiy V. S. , Melikyan L. P. , Egorov L. V.
Published: January 2023

Heterotaxy syndrome is a congenital malformation in which the internal organs of the chest and abdominal cavity have an abnormal location. People suffering from this syndrome have multiple complex defects in the heart, blood vessels, spleen, liver, lungs and other organs. Heterotaxy is a rare pathology that requires a multidisciplinary approach to diagnosis. This article demonstrates a rare case of heterotaxy observed in the pulmonology clinic of the Veltischev Institute.