bluuebunny/crossref_metadata_2025 huggingface dataset:
Monitoring Health Care Workers at Risk for COVID-19 Using Wearable Sensors and Smartphone Technology: Protocol for an Observational mHealth Study (Preprint)
Authors: Clingan Caroline A , Dittakavi Manasa , Rozwadowski Michelle , Gilley Kristen N , Cislo Christine R , Barabas Jenny , Sandford Erin , Olesnavich Mary , Flora Christopher , Tyler Jonathan , Mayer Caleb , Stoneman Emily , Braun Thomas , Forger Daniel B , Tewari Muneesh , Choi Sung Won
Published: April 2021

BACKGROUND

Health care workers (HCWs) have been working on the front lines of the COVID-19 pandemic with high risks of viral exposure, infection, and transmission. Standard COVID-19 testing is insufficient to protect HCWs from these risks and prevent the spread of disease. Continuous monitoring of physiological data with wearable sensors, self-monitoring of symptoms, and asymptomatic COVID-19 testing may aid in the early detection of COVID-19 in HCWs and may help reduce further transmission among HCWs, patients, and families.

OBJECTIVE

By using wearable sensors, smartphone-based symptom logging, and biospecimens, this project aims to assist HCWs in self-monitoring COVID-19.

METHODS

We conducted a prospective, longitudinal study of HCWs at a single institution. The study duration was 1 year, wherein participants were instructed on the continuous use of two wearable sensors (Fitbit Charge 3 smartwatch and TempTraq temperature patches) for up to 30 days. Participants consented to provide biospecimens (ie, nasal swabs, saliva swabs, and blood) for up to 1 year from study entry. Using a smartphone app called Roadmap 2.0, participants entered a daily mood score, submitted daily COVID-19 symptoms, and completed demographic and health-related quality of life surveys at study entry and 30 days later. Semistructured qualitative interviews were also conducted at the end of the 30-day period, following completion of daily mood and symptoms reporting as well as continuous wearable sensor use.

RESULTS

A total of 226 HCWs were enrolled between April 28 and December 7, 2020. The last participant completed the 30-day study procedures on January 16, 2021. Data collection will continue through January 2023, and data analyses are ongoing.

CONCLUSIONS

Using wearable sensors, smartphone-based symptom logging and survey completion, and biospecimen collections, this study will potentially provide data on the prevalence of COVID-19 infection among HCWs at a single institution. The study will also assess the feasibility of leveraging wearable sensors and self-monitoring of symptoms in an HCW population.

CLINICALTRIAL

ClinicalTrials.gov NCT04756869; https://clinicaltrials.gov/ct2/show/NCT04756869

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/29562
COVID-19 Vaccine Hesitation in Online Consumers: Social Media Textual Analysis (Preprint)
Authors: Sussman Kristen Leah , Bouchacourt Lindsay Marie , Bright Laura Frances , Wilcox Gary Burl , Mackert Michael , Norwood Aliza , Altillo Brandon
Published: April 2021

BACKGROUND

The COVID-19 pandemic continues to greatly impact the global community as we recently marked the one-year anniversary of the first cases of the disease. While many strides have been made in the medical community to produce several viable vaccines, much hesitancy exists within the public regarding the efficacy of the vaccines as well as their potential side effects.

OBJECTIVE

This study examines the public response to the COVID-19 vaccine by analyzing social media mentions of hesitancy.

METHODS

Brandwatch software was used to capture social mentions regarding vaccine hesitancy between September 1, 2020 and December 31, 2020 before undergoing a text analytic process using SAS text-mining software. Eight unique topics were identified before being further analyzed for themes in positive and negative sentiment.

RESULTS

The data indicate that there is mistrust and hesitancy surrounding the vaccines; however, positive themes also emerged surrounding the sources of the information (health care professionals, doctors, and government organizations). Pfizer was found to elicit both positive and negative emotions regarding their involvement with vaccine production. Overall, the negative sentiment surrounding the vaccines tended to dominate the social media conversation.

CONCLUSIONS

Through the use of credible communicators, COVID-19 vaccine hesitation may be mitigated. A combination of online and offline word-of-mouth strategies are suggested to reach relevant populations of interest. Topics of personal anecdotes of safety, effectiveness and recommendations among family are suggested as communication opportunities for frontline health care workers.
ДЛЯ ОБЕСПЕЧЕНИЯ ТЕХНОЛОГИЧЕСКОЙ НЕЗАВИСИМОСТИ СТРАНЕ НУЖЕН МАССОВЫЙ ПОТРЕБИТЕЛЬ ПЕЧАТНЫХ ПЛАТ
Authors: Семёнов В.
Published: April 2021

В статье обсуждается опыт ООО «ТЕХНОТЕХ» по освоению технологии производства базовых материалов для печатных плат. Рассматриваются проблемы отечественных производителей печатных плат, предлагается решение, создающее условия для устойчивого развития отрасли.
ДОВЕРЕННАЯ ЭКБ ДЛЯ ДОВЕРЕННЫХ АППАРАТНО-ПРОГРАММНЫХ ПЛАТФОРМ: ПРОБЛЕМЫ И ПУТИ РЕШЕНИЯ. Часть 1
Authors: Белоус А. , Солодуха В.
Published: April 2021

Рассмотрены основные концепции, тенденции, особенности развития относительно нового и стремительно развивающегося направления микроэлектроники – проектирования кибербезопасной ЭКБ для доверенных аппаратно-программных платформ.
Zoom y la educación en ciencias de la salud: ¿medio o mensaje?
Authors: Sánchez Mendiola Melchor , Fortoul van der Goes Teresa I.
Published: April 2021

Introducción: La pandemia de 2020 ha sido la fuerza más disruptiva en la historia para la educación en ciencias de la salud. Las medidas sanitarias de confinamiento y distanciamiento social obligaron a trasladar la mayoría de las actividades de enseñanza a la modalidad en línea, por lo que universidades y hospitales tuvieron que interactuar a través de modalidades digitales, incluyendo videoconferencias. La plataforma más usada para este fin es Zoom, por lo que es necesario analizar las bondades y limitaciones de esta aplicación en educación en ciencias de la salud.Objetivo: Proveer una actualización y reflexión crítica sobre el uso de Zoom en educación en profesiones de la salud.Método: Revisión narrativa de la literatura y ensayo crítico sobre el tema. El análisis se estructuró de la siguiente forma: uso de videoconferencias durante la pandemia; qué es Zoom, sus ventajas y desventajas; principios educativos y recomendaciones para su mejor uso; conclusiones.Discusión: Los avances tecnológicos de las últimas décadas generaron un escenario propicio para el uso masivo de videoconferencias en tiempo real durante la pandemia, lo que hubiera sido imposible a principios de siglo. La plataforma de Zoom ha sido una de las más utilizadas por su facilidad de uso e interfaz intuitiva. Como con cualquier tecnología en educación, es fundamental utilizar esta plataforma sustentándose en sólidos principios educativos, en lugar de solamente transferir la conferencia tradicional del aula física a la virtual. Es necesario transitar de la “educación remota de emergencia” a una educación en línea adecuadamente planeada, diseñada e implementada, que incluya múltiples herramientas de comunicación sincrónica y asincrónica como elementos del proceso, así como realizar investigación sobre su eficacia y efectos adversos.Conclusiones: La pandemia ha generado profundos cambios en la enseñanza de las profesiones de la salud, incluyendo el uso masivo de videoconferencias en tiempo real. Es necesario documentar estas experiencias y fundamentarlas con investigación de calidad.
KEPLER PLANETARY SYSTEMS: DOPPLER BEAMING EFFECT SIGNIFICANCE
Authors: Barbier H. , López E.
Published: April 2021

In the present work, in order to estimate the semi-amplitude of the radial velocity, we evaluate the contribution of the Doppler beaming effect to the phase curves of the all confirmed extrasolar planets (2776, September 2019), observed so far by the Kepler telescope. By modeling the tiny photometric variations (reflection, ellipsoidal and Doppler beaming effects) of the light curves, we found that the best observational data are in close agreement with the theoretical and published values of the amplitudes only for exoplanets: KOI-13b and TrES-2b. The derived values for the radial velocity also are in good agreement with those published by some authors. Furthermore, we found it necessary to introduce a third harmonic (3Φ) contribution into the KOI-13b and HAT-P7b light curve models, in order to decrease the residuals.
Hubungan persepsi risiko dan tawakal dengan perilaku protektif covid-19 di pesantren dan asrama
Authors: Zainurrahman Muhammad Zaki Afif , Agustin Neng Wita Juwita , Ma’rufi Amarria
Published: April 2021

Islamic boarding schools and dormitories are one of the clusters with a high spread of COVID-19. The high intensityof clustering activities in these clusters can increase the potential for the spread of COVID-19. This study aims todetermine the differences in the level of risk perception, protective behavior, and tawakal (surrender to God) betweenindividuals living in Islamic boarding schools/dormitories and the general public. This present study is a mixed-methodresearch with scales and an open-ended question. All participants (N = 91) were Muslim with an age range of 18-24years. The data were analyzed using t-test and correlation tests for the quantitative data, and thematic analysis forthe qualitative data. The level of risk perception among participants living in Islamic boarding schools/dormitories islower than that of participants who do not live in these two places. The protective behavior between the two groups ofparticipants did not have a significant difference. We found a positive correlation between protective behavior andtawakal attitudes among participants living in Islamic boarding schools/dormitories. This study provides a deeperunderstanding on the dynamics of attitudes and behavior in Islamic boarding schools and dormitories during theCOVID-19 pandemic. Protective behavior among muslims is not only related to risk perceptions of a pandemic, butalso to tawakal as a religious manifestation in dealing with calamities.
Combining hard and soft decoders for hypergraph product codes
Authors: Grospellier Antoine , Grouès Lucien , Krishna Anirudh , Leverrier Anthony
Published: April 2021

Hypergraph product codes are a class of constant-rate quantum low-density parity-check (LDPC) codes equipped with a linear-time decoder called small-set-flip (SSF). This decoder displays sub-optimal performance in practice and requires very large error correcting codes to be effective. In this work, we present new hybrid decoders that combine the belief propagation (BP) algorithm with the SSF decoder. We present the results of numerical simulations when codes are subject to independent bit-flip and phase-flip errors. We provide evidence that the threshold of these codes is roughly 7.5% assuming an ideal syndrome extraction, and remains close to 3% in the presence of syndrome noise. This result subsumes and significantly improves upon an earlier work by Grospellier and Krishna (arXiv:1810.03681). The low-complexity high-performance of these heuristic decoders suggests that decoding should not be a substantial difficulty when moving from zero-rate surface codes to constant-rate LDPC codes and gives a further hint that such codes are well-worth investigating in the context of building large universal quantum computers.
Empreender solidário: uma outra forma de conceber as relações sociais de produção
Authors: Alves da Silva Nogueira Kleiton Wagner
Published: April 2021

O crescimento do desemprego e a necessidade de pensar em uma outra economia possível faz da Economia Solidária uma opção para a reflexão em torno das relações sociais de produção na atualidade e qual o papel da Administração enquanto ciência nesse contexto. Com isso, o presente artigo apresenta como objetivo realizar uma reflexão entre a Administração Política e a Economia Solidária por meio de uma ação prática desenvolvida em uma comunidade carente do município de Campina Grande, Paraíba. Trata-se de um relato de experiência das atividades desenvolvidas que apresentou como principais resultados a identificação da necessidade de maior envolvimento da academia nas próprias comunidades e em especial o papel da Administração enquanto ciência que possui a gestão como objeto de estudo em realizar reflexões a respeito da necessidade de adotar uma perspectiva mais humana no provimento das condições de existência material da sociedade. Concluiu-se que a partir das atividades realizadas se faz imprescindível a atuação do Estado por meio de parcerias com a academia brasileira para um maior aproveitamento do potencial de criação de comunidades carentes para o próprio provimento das condições materiais.
Feira de projetos de intervenção: a experiência do ensino sobre formulação, gestão e avaliação de projetos públicos
Authors: Silveira Mauro , Assis Marcos Arcanjo de
Published: April 2021

O artigo discute um caso de ensino do processo de produção de políticas públicas em um curso de Administração Pública, sob a perspectiva da interdisciplinaridade. Trata-se da Feira de Projetos de Intervenção, trabalho desenvolvido no âmbito de duas disciplinas em que os alunos selecionam um problema público relevante e, aplicando metodologias de concepção e gerenciamento de projetos, desenham uma alternativa de solução. O objetivo do texto é registrar a experiência e, a partir dela, discutir aspectos relevantes para o desenvolvimento de estratégias interdisciplinares de ensino em cursos do Campo de Públicas. Adota-se uma perspectiva de interdisciplinaridade que vai além da interação entre distintas disciplinas, sendo fundamental, a troca, reciprocidade, diálogo e disposição para inovação dos envolvidos. Duas metodologias são aplicadas a Feira: o Marco Lógico, que fornece referências objetivas para a concepção, gestão e avaliação de projetos; e as boas práticas do Project Management Institute, metodologia baseada em áreas de conhecimentos e grupos de processos adequados ao gerenciamento de projetos. Cinco edições do trabalho já foram realizadas, resultando no desenho de 89 projetos. A cada edição, inovações na dinâmica foram incorporadas, ampliando as potencialidades e os aprendizados sobre a interdisciplinaridade na Administração Pública. Destacam-se a importância da articulação de teorias e métodos para compreensão de situações problema complexas, a experiência, mesmo simulada, dos reveses da prática administrativa no setor público, a relevância da abertura para a inovação e para o trabalho em parceria entre os docentes envolvidos, além de dificuldades instrumentais sobre o ensino do processo de produção de políticas públicas.
Desenvolvimento sustentável de três comunidades atingidas pela construção de uma usina hidrelétrica
Authors: Ferreira Patricia Aparecida , Lima Marina Aparecida , Lima Andreina Del Carmen Camero de
Published: April 2021

O caso apresenta uma narrativa sobre os impactos da construção de  uma usina hidrelétrica em  três comunidades e as estratégias adotadas pelo consórcio empreendedor para mitigar tais  impactos. Espera-se com este caso demonstrar que a construção de usina não apresenta somente impactos ambientais, mas também transformações políticas, sociais, culturais e econômicas no território em que será alocada. O caso também elucida alguns elementos para que os empreendedores obtenham o licenciamento para construção e operação de uma usina, no entanto, as questões orientadoras para sua análise não recaem sobre a legislação brasileira, mas, sobretudo, instigam um olhar para as relações entre o meio ambiente, o empreendimento e a sociedade. Propõe-se como referência teórica para estudar o caso, as discussões sobre o desenvolvimento sustentável, como uma proposta de desenvolvimento diferenciada, imbuídas de uma crítica ao reducionismo econômico e que consideram as dimensões sociais, culturais, econômicas, ambientais e políticas.
Quantitative Longitudinal Antibody Monitoring in a COVID-19 Outpatient Case Series: Relations of IgM/IgG Dynamics to Anosmia and Ageusia
Authors: Gil Nathalie , Heneriz Jenny , Diaz Dennis , Tomas Mike , Ruaño Gualberto , Cruz Raul
Published: April 2021

A case series of 22 patients with confirmed SARS-CoV-2 infection and
Corona Virus Disease 2019 (COVID-19) symptoms was followed in a primary
care clinic. We provided quantitative and longitudinal profiling for
SARS-CoV-2 IgM and IgG with a point of care device. Half the patients
had a history of anosmia or ageusia. IgM and IgG responses were highly
heterogeneous quantitatively and temporally. We determined that clinical
symptomatology of chemosensory loss correlated with lesser but sustained
titers of IgM and IgG whereas normal chemosensation correlated with
transiently higher but rapidly declining antibody levels.
Oncologic surgical resection with intravascular covered stent placement in patients with carotid artery encased by metastatic cancer---Our experience with 5 patients
Authors: Liu Kai , Zhang Haidong , Jiang Huanyu , Gong Shanchun , Lyu Xianjun , Yu Zhenkun
Published: April 2021

Importance: Tumor encasement of the common carotid artery (CCA) and/or
the internal carotid artery (ICA) in patients with advanced head and
neck tumors represents a significant surgical challenge. At present,
there are few reports on the treatment approach that can achieve the
maximal oncological resection and reduce the difficulty of operation
without affecting the carotid artery blood flow. Objective: To examine
whether the combination of oncologic complete tumor resection and
intravascular covered stent placement is more advantageous in the
management of advanced head and neck cancer. Design, Setting, and
Participants: Five patients with advanced head and neck squamous cell
carcinoma (AHNSCC) invading one side of the carotid artery were
retrospectively enrolled. The contrast-enhanced computed Tomography (CT)
and angiography were performed to assess the severity of extrinsic tumor
compression to the carotid artery. Covered stent was placed
intra-arterially at least 1 cm proximal and distal beyond the area of
tumor involvement. The tumor and the involved carotid artery were
resected, and pectoralis major flap transfer was utilized for coverage
of the great vessels supported with intra-arterial covered stent. Main
Outcomes and Measures: Efficacy of oncologic complete tumor resection
combined with endovascular stent placement. Results: The post-stenting
demonstrated an improvement in the appearance and caliber of the
affected carotid artery. Four patients experienced transient bradycardia
and hypotension. All five patients underwent R0 resection.
Postoperatively, the flap all had rich vascularity and healing. Three
patients underwent adjuvant radiotherapy or chemoradiation. With median
follow-up 6.5 months, one patient died of multiple organ failures at 6.5
months after surgery; one patient developed tracheal stoma recurrence
and treated with salvaged surgery; the three other patients had no
disease recurrence in their last follow-ups. Conclusions and Relevance:
Surgical resection with intravascular covered stent placement could
potentially achieve the maximal oncological resection without compromise
carotid artery blood flow in patients with carotid artery encased head
and neck cancer.
Restoration of malperfusion during repair of thoracic aortic dissection
Authors: Shuhaiber Jeffrey , Labinskyy Volodymyr
Published: April 2021

A 46- year old male, during intense physical activity, sustained
malperfusion of the lower extremities from Type A thoracic aortic
dissection. We took him to the operating room. emergently and perfusing
both lower extremities using a modified straight graft with side to side
anastomosis to one limb and end to side anastomoses to the inflow
perfusion and contralateral limb. The patient was successfully
discharged and remained to be doing well. for four years.
A pedunculated esophageal chondromatous hamartoma in a child
Authors: Iozsa Dan-Alexandru , Puscasu Maria , Cirstoveanu Catalin , Constantin Vlad , Dumitriu Anca , Paunica Stana , Ionescu Nicolae
Published: April 2021

Esophageal tumors are uncommon in pediatric population and most of them are benign. Esophageal hamartomas have been reported extremely rare in children. These can present as intramural tumors of the esophageal wall or as polyps. Dysphagia is the main symptom described in their case, but other specific symptoms are also reported. Such symptoms encountered in clinical practice are represented by obstructive apnea episodes and bradycardia, poor weight gain, epigastric or retrosternal pain, hematemesis or melena, dysphonia or tracheal sounds. Diagnosis can be delayed due to the insidious onset and non-specific symptoms, therefore patient’s compliance to follow-up and broad, careful evaluation are mandatory. Preoperative imagistic assessment is extremely important for a precise definition of the tumor’s anatomical relations, especially when facing large tumors located in the posterior mediastinum. Herein we report a case of a large chondromatous polypoid hamartoma of the esophagus in a 9 years old boy, emphasizing over the diagnosis and surgical challenges we have met, along with comments on illustrative similar cases reported in the literature.
"Modern approaches for antiandrogen-resistant prostate cancer therapy
Authors: Voinea Felix , Mazilu Laura , Micu Ioan , Suceveanu Adrian , Iliescu Madalina , Dumitru Andrada , Constantin Vlad , Paunica Ioana , Suceveanu Andra
Published: April 2021

Prostate cancer represents the leading malignant tumor in men over 50 years of age with 400,000 new cases being diagnosed yearly in Europe. Even if the incidence rate is higher than the mortality rate, still there is an increasing trend when speaking of its mortality. The increasing incidence of the metabolic syndrome, the unhealthy lifestyle, the high lipid and Calcium intake, the high spread of infections with Human Papilloma Virus, Human Herpes Virus, the excess of androgen consumption and the longer life expectancy, are few of the main causes of prostate cancer increasing incidence. The new systemic therapies such as immunotherapy with Checkpoint Inhibitors or Poly, ADP-Ribose Polymerase inhibitors and local experimental procedures addressing tumor destruction, such as High- Intensity Focused Ultrasound, the Cryo and Focal Laser Ablation, provide good outcomes and become new promising tools for prostate cancer therapy. Physicians consider these methods worth using; the efficacy of some specific categories of patients being arguments for their use in the current protocols even though solid data regarding the improvement of global mortality rates are not yet published. The current article focuses on the newest systemic and local experimental treatment tools highlighting their benefits, especially for hormone-resistant prostate cancer.
A comprehensive analysis of postpartum depression and delivery characteristics: a cross-sectional study
Authors: Uzun Navdar , Tekin Mustafa , Uzun Fulya
Published: April 2021

Objective: We attempted to identify risk factors for postpartum depression (PPD) by evaluating individuals in terms of their birth patterns, as well as other characteristics, including income level, smoking habits, number of children, age, and history of antidepressants. Methods and results: Participants completed a questionnaire consisting of three sections: demographic characteristics, delivery characteristics, and Edinburgh Postpartum Depression Scale. Participants with a depression medical history had a higher depression level during the postpartum. There were significant correlations between postpartum depression, the husband’s working status, the desire fo r the pregnancy, and the patient’s depression medical history. PPD levels did not differ for other birth-related variables. Conclusions: It is important to use appropriate screening tools to identify mothers with PPD in the community. It is also important to instruct mothers about how to care for both their babies and themselves. For this reason, the mother should be monitored for the first six months postpartum, and social - familial support should also be monitored.
Diabetic Kidney Disease Alters the Transcriptome and Function of Human Adipose-Derived Mesenchymal Stromal Cells but Maintains Immunomodulatory and Paracrine Activities Important for Renal Repair
Authors: Hickson LaTonya J. , Eirin Alfonso , Conley Sabena M. , Taner Timucin , Bian Xiaohui , Saad Ahmed , Herrmann Sandra M. , Mehta Ramila A. , McKenzie Travis J. , Kellogg Todd A. , Kirkland James L. , Tchkonia Tamar , Saadiq Ishran M. , Tang Hui , Jordan Kyra L. , Zhu Xiangyang , Griffin Mathew D. , Rule Andrew D. , Wijnen Andre J. van , Textor Stephen C. , Lerman Lilach O.
Published: April 2021

Mesenchymal stem/stromal cells (MSC) facilitate
repair in experimental diabetic kidney disease (DKD). However, the hyperglycemic
and uremic milieu may diminish regenerative capacity of patient-derived therapy.
We hypothesized that DKD reduces human MSC paracrine function. Adipose-derived MSC from 38 DKD participants
and 16 controls were assessed for cell surface markers, tri-lineage differentiation,
RNA-sequencing (RNA-seq), in vitro function
(co-culture or conditioned medium experiments with T cells and human kidney
cells [HK-2]), secretome profile, and cellular senescence abundance. The
direction of association between MSC function and patient characteristics were
also tested. RNA-seq analysis identified 353 differentially expressed genes and
downregulation of several immunomodulatory genes/pathways in DKD- vs. Control-MSC. DKD-MSC phenotype,
differentiation, and tube formation capacity were preserved but migration was reduced.
DKD-MSC with and without interferon-γ priming inhibited T-cell proliferation
greater than Control-MSC. DKD-MSC-medium
contained higher levels of anti-inflammatory cytokines (indoleamine 2,3-deoxygenase-1
and prostaglandin-E2) and pro-repair factors (hepatocyte growth factor and stromal
cell-derived factor-1) but lower Interleukin-6 vs. Control-MSC-medium. DKD-MSC-medium
protected high glucose plus transforming growth factor-β-exposed HK-2 cells by reducing apoptotic, fibrotic and
inflammatory marker expression. Few DKD-MSC functions were affected by patient
characteristics including age, gender, body mass index, hemoglobin A1c, kidney
function or urine albumin excretion. However,
senescence-associated-β-galactosidase activity was lower in DKD-MSC from
participants on metformin therapy. Therefore, while DKD altered the transcriptome and migratory
function of culture-expanded MSC, DKD-MSC functionality, trophic factor
secretion and immunomodulatory activities contributing to repair remained
intact. These observations
support testing patient-derived MSC therapy and may inform preconditioning
regimens in DKD clinical trials.
Brown Adipose Tissue Volume and Fat Content are Positively Associated with Whole-Body Adiposity in Young Men, Not in Women
Authors: Sanchez-Delgado Guillermo , Martinez-Tellez Borja , Acosta Francisco M. , Virtue Samuel , Vidal-Puig Antonio , Gil Angel , Llamas-Elvira Jose M , Ruiz Jonatan R
Published: April 2021

Human brown adipose tissue (BAT) volume has been consistently claimed as
inversely associated with whole-body adiposity. However, recent advances in the
assessment of human BAT suggest that previously reported associations may have
been biased. The present cross-sectional study investigates the association of
BAT volume, mean radiodensity, and 18F-fluordeoxyglucose (18F-FDG)
uptake (assessed via a static positron emission tomography-computerized
tomography (PET-CT) scan after a 2-hour personalized cold exposure) with whole-body
adiposity (measured by dual-energy X-ray absorptiometry) in 126 young adults (42
men / 84 women; 25±5 kg/m2). BAT volume, but not 18F-FDG
uptake, was positively associated with body mass index (BMI), fat mass, and visceral
adipose tissue mass in men, but not in women. These associations were
independent of the date when the PET-CT was performed, insulin sensitivity and
body surface area. BAT mean radiodensity, an inverse proxy of BAT fat content,
was negatively associated was with BMI, waist circumference, fat mass and visceral
adipose tissue mas in men and with percentage fat mass in women. These results refute the
widely held belief that human BAT volume is reduced in obese persons, at least
in young adults, and suggest that it might even be the opposite in young men.
A Carl-Gustaf M4 típusú, többcélú hátrasiklás nélküli reaktív fegyver
Authors: Zsig Zoltán
Published: April 2021

A Zrínyi Honvédelmi és Haderőfejlesztési Program részeként a Magyar Honvédség 2019-ben Carl-Gustaf M4 típusú hátrasiklás nélküli kézi páncéltörő fegyvereket szerzett be, amelyekkel új képességek birtokába jutottak a katonáink. A svéd hadiipar évtizedek óta gyárt különböző működési elvű, hordozható páncéltörő eszközöket, amelyek egyik legsikeresebb típusa a 84 mm-es Carl-Gustaf M4 többcélú reaktív fegyver.
The changing face of Australian data reforms: Impact on pharmacoepidemiology research
Authors: De Oliveira Costa Juliana , Bruno Claudia , L Schaffer Andrea , Raichand Smriti , A Karanges Emily , Pearson Sallie-Anne
Published: April 2021

ObjectiveA wealth of data is generated through Australia’s universal health care arrangements. However, use of these data has been hampered by different federal and state legislation, privacy concerns and challenges in linking data across jurisdictions. A series of data reforms have been touted to increase population health research capacity in Australia, including pharmacoepidemiology research. Here we catalogued research leveraging Australia’s Pharmaceutical Benefits Scheme (PBS) data (2014–2018) and discussed these outputs in the context of previously implemented and new data reforms.
MethodsWe conducted a systematic review of population-based studies using PBS dispensing claims. Independent reviewers screened abstracts of 4,996 articles and 310 full-text manuscripts. We characterised publications according to study population, analytical approach, data sources used, aims and medicines focus.
ResultsWe identified 180 studies; 133 used individual-level data, 70 linked PBS dispensing claims with other health data (66 across jurisdictions). Studies using individual-level data focussed on Australians receiving government benefits (87 studies) rather than all PBS-eligible persons. 63 studies examined clinician or patient practices and 33 examined exposure-outcome relationships (27 evaluated medicines safety, 6 evaluated effectiveness). Medicines acting on the nervous and cardiovascular system account for the greatest volume of PBS medicines dispensed and were the most commonly studied (67 and 40 studies, respectively). Antineoplastic and immunomodulating agents account for approximately one third of PBS expenditure but represented only 10% of studies in this review.
ConclusionsThe studies in this review represent more than a third of all population-based pharmacoepidemiology research published in the last three decades in Australia. Recent data reforms have contributed to this escalating output. However, studies are concentrated among specific subpopulations and medicines classes, and there remains a limited understanding of population benefits and harms derived from medicines use. The current draft Data Availability and Transparency legislation should further bolster efforts in population health research.
Menyikapi Nusyuz dalam Keluarga: Ikhtiar Mewujudkan Keluarga Harmonis (Studi Komparasi Pendapat Imam Syafi'i dan Hanafi)
Authors: Hamdi Saibatul , Ulumiddin Ahya
Published: April 2021

This study discusses the wife's disobedient behavior towards her husband. This rebellious behavior called nusyuzas mentioned in the Qur'an in An-Nisa verse 34. This study is important to discuss because the present-day reality shows that many family cases are not harmonious due to the wife who is disobedient to her husband. This study aims to describe the concept of nusyuzaccording to the Qur'an and also interpreted by Imam Shafi'i and Hanafi. In addition, it also aims to understand the criteria of nusyuzand the way to solve nusyuzin the Qur'an and in the view of Imam Shafi'i and Hanafi. The method used is the library research, namely by examining various related references in order to obtain a conclusion about nusyuzas contained in the Qur'an. Through this study, it can be seen that: 1) Nusyuzis the injustice committed by the wife towards her husband in the form of wife disobedience, 2) The criteria of nusyuzaccording to Al-Qur'an and the opinion of Imam Shafi'i and Hanafi are women who are proud and against their husbands and 3) The completion of the wife of nusyuzis done in three ways, namely giving advice, separating the bed, and hitting it. If the three steps are unsuccessful then it need an alternative which mediation. With regard to the sequence of these stages according to Imam Hanafi it must be done in an orderly manner but according to Imam Shafi'i one may choose which steps are the most appropriate to do.
Pendidikan Karakter Analisis Pemikiran Ibnu Miskawaih
Authors: Rahayu Fitriani
Published: April 2021

Character education is a important thing to be instilled in school-age children given the many moral crises that have occurred among teenagers lately. In addition to, Indonesia lacks figures who can be used as a role model. That done because many public figures commited the crimes such as corruption, collusion, prostitution, and so on. Ibnu Miskawaih is one of the Islamic philosophers who touches on the concept of character education in his book tahzib al-akhlak wa tahir al-a'raf. By literature studies, this paper attempts to describe the concept of character education offered by Ibnu Maskawaih, namely The Golden(The Doctrin of The Mean). He stated that human character is built from four foundations, namely restraint, courage, wisdom, and justice. The character values developed by Ibnu Maskawaih can be used as a reference for the implementation of education in Indonesia. The expected values or characters are the formation of personality based on the norms of religion, culture and ethics of the Indonesian nation. So, the thought of Ibn Miskawaih is so suitable for using in morality crisis era.
ESTIMATING STABILITY OF STRUCTURAL AND BRIGHTNESS PROPERTIES IN IMAGE DIGITAL PROCESSING
Authors: Afonin Viktor , Savkina Anastasia V. , Nikulin Vladimir
Published: April 2021

The article considers determining the stability assessment of the structural and brightness properties of raster images. The stability assessment refers to the ability of preserving the image properties due to the original image processing by filtering. Halftone versions of the full-color images presented in the RGB color space are accepted as original images. The grayscale images are filtered using the Gaussian, Wiener, and median filtration algorithms. The next step is to use one of the variants of the SSIM algorithm to obtain the structural similarity index between the control halftone image and the filtered image. In order to create a relative and dimensionless metric there has been calculated the area of the polygon S set by the values of the similarity indices relative to the control grayscale image, and the area of the rectangle Sp that contains the area of the polygon S. Images from the international image database TID2008 (image database 2008), TID2013 (image database 2013) were taken as test bitmaps. The official coats of arms of the Russian Federation entities – territories, regions, republics, etc. - were also considered. The resulting stability score is determined either as the geometric mean of the four calculated values, or as their arithmetic mean. The results of testing the groups of bitmap images that are united by a common theme or purpose are presented. From each group of images, the maximum and minimum values of the estimates of the image stability to structural and brightness changes are determined in accordance with the developed heuristic algorithm. The results obtained can be used for comparative evaluation of competing images in order to select the most resistant to structural and brightness changes.
Effects of Solid and Liquid Vermicompost Application on Bean Growth and Common Bacterial Blight Disease in Different Growth Medium
Authors: ÖZTÜRKCİ Yusuf , AKKÖPRÜ Ahmet
Published: April 2021

In this study, the effect of solid and liquid forms of vermicompost on plant growth and bacterial common blight disease in different growth media were investigated. Vermicompost was applied at the rate of 1/100, 1/150, 1/200 in liquid form and vermicompost in solid form at the rate of 10%, 20%, 40% to peat and soil growing medium. The pathogen, Xanthomonas axonopodis pv. phaseoli (Xap), was applied to the leaves by spraying at a concentration of 107 CFU mL-1. The effects of applications on plant growth parameters, total chlorophyll content, and disease severity were evaluated. It was determined that the effects of the applications varied according to vermicompost form and growth medium. Liquid vermicompost applications displayed more positive effects on root growth in the soil growing medium. However, the application of liquid vermicompost did not affect disease severity. It was observed that the 40% dose of vermicompost in solid form inhibited plant growth and caused chlorosis in both growth media. However, 10 and 20% of doses had no adverse effects on plant growth. Also, the application of 10% solid vermicompost to peat growing medium reduced the disease development by 48%. In soil growth medium, application doses of 10% and 20% prevented disease development by 62% and 54%.
Research on Mould and Aflatoxin Contamination Levels of Feeds Used in Trout Farms of Adana (Turkey)
Authors: GÖLGE Özgür , AKTÜRE Ayşegül , AYDIN Rozelin
Published: April 2021

This research was conducted to analyze the mould counts and aflatoxin contamination levels of different types and sizes of feed used in trout farms of Adana. Totaly 33 different feeds supplied from 15 trout farms of Adana (Turkey) were analysed for moulds and aflatoxins (AFB1, AFB2, AFG1 and AFG2) between July-December 2010. To identify mould counts; the samples were incubated in the aerobic conditions at 25 ± 1 °C for five days by using Dichloran Rose Bengal Chloramphenicol Agar (DRBC). Aflatoxins were determined by using liquid-solid extraction and recoveries were obtained 70.00% to 112.20%. The precision of measured values of mould and aflatoxin analysis methods was calculated with the results of repeatability and reproducibility. The bias, expressing the accuracy value, varies between 4.312 and 12.909. Although moulds were found in 12 of 33 analysed samples (36.30%): aflatoxins were determined 8 out of 33 analysed samples (24.25%). Positive sample’s range were 3.08-4.86 log10 kob g-1 moulds and 0.21–0.90 g AFB1 kg-1 (ppb) of trout feeds. As a result, this research showed that none of the trout feeds used in trout farms of Adana has aflatoxins above Turkey legal limits.
Farklı Zamanlarda Ekilen Bazı Yem Bezelyesi (Pisum sativum ssp.arvense L.) Çeşitlerinin Tohum ve Kesinin Besin Değerleri
Authors: KESKİN Bilal , TEMEL Süleyman , EREN Barış
Published: April 2021

Bu araştırma Iğdır ekolojik şartlarında kışlık ve yazlık olmak üzere 6 farklı ekim zamanı (Ekim sonu Kasım başı ve Kasım sonu, Mart başı, Mart sonu, Nisan başı)’nda, 4 farklı yem bezelyesi (GAP Pembesi, Kirazlı, Özkaynak ve Taşkent) çeşidinin tohum ve keslerinin yem olarak besin değerleri belirlenmiştir. Deneme Iğdır Üniversitesi Tarımsal Uygulama ve Araştırma Merkez Müdürlüğünün deneme sahasında 2018-2019 ve 2019-2020 yıllarında olmak üzere 2 yıl süreyle tesadüf bloklarında bölünmüş parseller deneme desenine göre 3 tekerrürlü olarak kurulmuştur. Araştırmada yem bezelyesi’nin tohumda ham protein oranı (tohum-HP), kes ham protein oranı (kes-HP kes nötr çözücülerde çözünemeyen lif (kes-NDF), asit çözücülerde çözünemeyen lif (kes-ADF), kuru madde sindirilebilirliği (kes-KMS), kuru madde tüketimi (kes-KMT), sindirilebilir enerji (kes-SE), metabolik enerji (kes-ME), ve nispi yem değeri (kes-NYD) belirlenmiştir. Araştırma sonuçlarına göre, tohum-HP oranı, kes-HP oranı, kes NDF oranı, kes-ADF oranı, kes-KMT oranı ve kes-NYD değeri Nisan ayı başındaki ekimlerde en iyi değerlere ulaştığı görülmüştür. Çeşitler arasında ise en iyi yem değerleri Özkaynak çeşidinde belirlenmiştir. Araştırma sonuçlarına göre Iğdır ekolojik şartlarında yem bezelyesi yetiştiriciliğinde tohum ve kes en iyi yem değerlerinin alınabilmesi için Özkaynak çeşidinin ekilmesi gerekmektedir. Diğer taraftan Nisan başında yapılacak ekimlerde kes kalitesinin daha yüksek olacağı belirlenmiştir.
Domates (Lycopersicon esculentum Mill.) Meristemlerinin In Vitro Gelişimi Üzerine Bazı Bitki Büyüme Düzenleyicilerinin Etkisi
Authors: UYSAL Hüseyin , AKSIN Özlem , GÜZEL Gizem , KÜÇÜKUNCULAR Aysu
Published: April 2021

Bu çalışma in vitro koşullarda yetiştirilen domates bitkilerinden elde edilen meristemlerin farklı konsantrasyonlarda BAP (6-benzil amino pürin- sitokinin hormonu) ve İAA (İndol-3-asetik asit- oksin hormonu) içeren besi ortamlarındaki gelişimini araştırmak amacıyla gerçekleştirilmiştir. Araştırmada temel besi ortamı olarak MS (Sigma Aldrich, Katalok No:M5519) besi ortamı kullanılmış olup bu ortama 0.1, 0.5 ve 1.0 mg l-1 oranlarında ayrı ayrı BAP ve İAA ilave edilmiş yine kullanılan temel besi ortamına 0.1 mg l-1 BAP + 0.5 mg l-1 İAA ve 0.5 mg l-1 BAP + 0.1 mg l-1 İAA oranlarında sitokinin ve oksin hormonları birlikte ilave edilmiştir. Araştırma sonucunda tam bir bitki oluşumu bakımından en yüksek başarı oranı %61.11 ile 0.5 mg l-1 BAP + 0.1 mg l-1İAA içeren besi ortamından elde edilmiştir. Hiçbir hormon kullanılmayan yalın besi ortamı toplam direk rejenerasyon (sürgün, kök, sürgün + kök oluşumu) bakımından en iyi sonucu verirken (%100), kallus oluşumu bakımından ise 0.5 mg l-1 BAP + 0.1 mg l-1 İAA içeren ortam en iyi sonucu (%100) vermiştir. Yine kalluslardan bitki rejenerasyonu bakımından en iyi sonucu (%340) 0.5 mg l-1 BAP + 0.1 mg l-1 İAA içeren MS besi ortamı ortaya koymuştur. Araştırmanın genel sonucu değerlendirildiğinde yüksek konsantrasyonda kullanılan BAP veya İAA hormonlarının domates meristemlerinde kallus oluşumunu teşvik ettiği saptanmıştır.
The Potential of Carbon Footprint Reduction of a Mid-Rise Residential Building in Sarawak
Authors: Yaman Nurdiyanah , Abd Rashid Ahmad Faiz
Published: April 2021

Carbon emission is released into the atmosphere as the result of various activities due to rapid urbanisation and thus contributed to global warming and climate change. The government has taken various initiatives to reduce the impact, including from the construction industry in order to support the carbon footprint reduction of 40% as pledged by the Prime Minister. Various strategies, such as the Malaysian Carbon Reduction and Environmental Sustainability Tool (MyCREST), have been established to promote green building development in Malaysia. Recent studies suggested that the selection of sustainable materials can reduce the overall carbon emission of a building, but the cost has been identified as the main barriers. This paper aims to analyse the potential of carbon footprint reduction by using sustainable material in mid-rise residential building and subsequently to evaluate the cost implication. The impact of the conventional and the selected sustainable materials was assessed using data from the MyCREST tool while the data for cost analysis were taken from various sources of cost data such as JKR Rates online (RATOL), JKR Sarawak Schedule of Rates (SOR), and previous research. The results show that the sustainable materials such as 30% of Blast Furnace Slag (BFS) concrete mixture, Aerated Autoclaved Concrete (AAC) block, and recycled steel roof truss has the potential to reduce the carbon emission. The findings also show that sustainable materials are slightly cheaper than the conventional materials except for the AAC block and clay roof tiles. Therefore, the potential of carbon emission reduction approach by using MyCREST as a guideline tool can assist in the reduction of the environmental impact of buildings.Keywords: Carbon emission, sustainable building materials, cost implication.
Employability Forecast Among Construction Management from The Employer’s Perspective in Malaysia Construction Industry
Authors: Mohd Yussof Farrah Norizzah , Hasbi Haifa Afieqah , Ahmad Zawawi Emma Marinie
Published: April 2021

The tertiary education institutions in Malaysia are facing increasing demands from employers and stakeholders to ensure the graduates to be equipped with relevant skillset needed to secure a placement in the industry. The question arises, what are the skillsets required by employers contribute to the research gap which led to a comprehensive understanding on the expectation of employers towards the graduate’s employability. This study determined the employers' perspective skills by referring to five (5) field of employment consist of Developer, Contractor, Consultant, Supplier and Entrepreneur which consume of 57 (38%) respondents from 150 questionnaires distributed both on-site and on-line survey using random sampling technique. The content was referred on the program offered by Bachelor of Science in Construction Management, Universiti Teknologi MARA (UiTM). An exploratory factor analysis (EFA) was conducted using six (6) main categories of courses on hard skill to achieve the objective one and seven (7) soft skills to accomplish objective two. The finding indicates Project Management, Measurement and Estimating and Legal Study knowledge of hard skill critically required, whilst, interpersonal and communication soft skill is crucially needed. Those skills reveal as the fundamental knowledge in handling a construction works. In summary, this study able to facilitate the gap between graduates’ skills and employers’ expectation by providing a sufficient guidance platform referring to the respective field of employment as well as provides a significance implication to the educational institutions to align the program outcome toward the needs of the industry.Keywords: employability, forecast, graduates, employer
Visitors’ Preferences on Seasonal Accommodation for the Rainforest World Music Festival
Authors: Mohd Ariffin AR , MOHAMED JAMEL MOHD KHAIRIL NAIM
Published: April 2021

Sarawak Cultural Village (SCV) is an award-winning open-air living museum of Sarawak has been the host to the three days annual Rainforest World Music Festival (RWMF) since 2005. Every year, thousands of visitor flock to SCV grounds to experience the rich Sarawak culture, live performances and celebrations that it offers. Due to its popularity, each year the number of visitors increases with regulars and newcomers. This has created a spike in accommodation demands for the area of Santubong. Unfortunately, the growth of visitors is not supported by adequate desired accommodations within the area. Thus, the objectives of this paper are to identify an ideal seasonal accommodation type and desired basic facilities required during RWMF. Quantitative analysis is incorporated in this research through collection of data gathered from online survey. Set of questionnaires was distributed to the former visitors seeking their views on the seasonal accommodations and facilities preferred. Based on the results of the data collected, it provided some understanding on the seasonal accommodations and facilities that are suitable for RWMF. This finding consequently could help provide a feasible and practical solution towards the spike demand for accommodation facilities during the RWMF.Keywords: Seasonal Tourism, Festival, Accommodation, Facilities
TRADUCIENDO A JOSEPH ADDISON: PROBLEMAS Y DESAFÍOS
Authors: Martín Párraga Javier
Published: April 2021

El presente artículo analiza los problemas que implica traducir los textos periodísticos de opinión de Joseph Addison, figura clave de las letras inglesas del siglo XVIII y uno de los padres del periodismo moderno. Para llevar a cabo este objetivo, nos centraremos en un artículo publicado en The Spectator el día 8 de marzo de 1711.