bluuebunny/crossref_metadata_2025 huggingface dataset:
The English guitar and the forgotten guitar repertoire of the second half of the 18th century
Authors: Żegleń-Włodarczyk Małgorzata
Published: April 2023

The time leading up to one of the most important periods in the history of guitar music – “the golden age of the guitar” in the first half of the 19th century – was the heyday of European cities such as London, Paris, Vienna or Dresden. Music was the main source of entertainment for royalty and high society, and numerous music publications, sheet music editions and instrument hand-books were being created. Manufactures tried to outdo each other in structural innovations, refin-ing and patenting increasingly interesting instruments. One such instrument was the immensely pop-ular English guitar (guittar), which differed in design and tuning from the instrument we know today. At present, it would be futile to look for the guitar repertoire of the second half of the 18th century on concert stages or in academic curricula (with a few exceptions, such as Luigi Boccheri-ni's quintets or Giuseppe Antonio Brescianello's partitas), and English music is almost nowhere to be found. It is, to a large extent, undiscovered and nearly forgotten. Bringing it back to life will not only provide insight into the design and performing capabilities of the now unknown guittar (as well as its distinctive playing technique, fingering and articulation) and allow us to learn more about the works composed for the instrument (and their characteristic features), but – above all – give a full picture of the evolving aesthetics of the 18th century. These compositions will also fill the existing gap in the guitar repertoire of the second half of the 18th century, offering broad prospects for their performance in the future. The most important consequence of that is the preservation of the continuity of guitar literature from the Renaissance to the present day, and the resulting possibility to make the world described in Leopold Mozart’s or Carl Philipp Emanuel Bach’s treatises tangible.
Computed tomography-guided Gasserian ganglion interventions for cancer-related facial pain in patients with complex anatomy: Insights and recommendations
Authors: González-Casarez Ale Ismael , Santamaría-Montaño Germán Gerardo , Plancarte-Sánchez Ricardo , Guillén-Núñez María Rocío , Juárez-Lemus Ángel Manuel , Hernández-Porras Berenice Carolina , Samano-García Marcela , Rocha-Romero Andrés
Published: April 2023

Background: The Gasserian ganglion is a well-known target for facial pain management, and patients with cancer present an anatomical challenge owing to tumor progression or treatment itself. Computed tomography (CT) is an alternative method for guiding these procedures.Methods: This was an observational retrospective analysis of patients with cancer-related facial pain who underwent CT-guided Gasserian ganglion interventions using local anesthetics, local anesthetics with steroids, phenol, and radiofrequency. Demographic, clinical, and procedure-related variables were collected from January 1, 2015, to December 30, 2018, at the National Cancer Institute. Data distribution was determined using the Kolmogorov–Smirnov test. A paired sample t-test (with a cut-off of P < 0.05 for statistical significance) was used for comparing outcome.Results: We observed a significant reduction in numerical rating scale (NRS) and douleur neuropathique 4 (DN4) scores from 7.6 ± 1.4 and 4.4 ± 1.4 to 3.2 ± 2.0 and 2.2 ± 1.4 points, respectively (P < 0.001). After the procedure, 70.8% of the patients were satisfied; 16.7% were very satisfied, and 12.5% were unsatisfied. No intra- or postoperative complications were observed. The most common neoplasms were head and neck tumors (83.3%).Conclusions: Our data suggest that CT guidance is an effective and safe option for managing cancer-related facial pain in patients with complex anatomy, resulting in a significant reduction in pain, high satisfaction rates, and no mechanical complications. Future research should aim to refine the role of CT guidance in multimodal pain management in this population.
Effect of sevoflurane-remifentanil and propofol-remifentanil anesthesia on glycocalyx shedding during deep inferior epigastric perforator flap breast reconstruction: a prospective randomized, controlled trial
Authors: Lee Bahn , Shin Hye Jung , Kweon Ki Hong , Kim Na Young
Published: April 2023

Background: The endothelial glycocalyx (EG) is an important structure that regulates vascular homeostasis. Deep inferior epigastric perforator (DIEP) flap is expected to cause substantial EG breakdown owing to the long procedural duration and ischemia– reperfusion injury. This prospective, randomized, controlled study aimed to compare syndecan-1 levels during sevoflurane-remifentanil and propofol-remifentanil anesthesia in patients who underwent DIEP flap breast reconstruction.Methods: Fifty-one patients were randomized to either sevoflurane (n = 26) or propofol (n = 25) groups. Anesthesia was maintained with remifentanil in combination with either sevoflurane or propofol. The primary endpoint was the concentration of serum syndecan-1 measured at 1 h after surgery.Results: Fifty patients (98.0%) completed the study. Patients in the propofol group had significantly lower levels of syndecan-1 than patients in the sevoflurane group at 1 h after operation (23.8 ± 1.6 vs. 30.9 ± 1.7 ng/ml, respectively; Bonferroni corrected P = 0.012). There were no significant differences between groups in postoperative complications. The postoperative hospital stay was 8.4 ± 2.5 days in the sevoflurane group and 7.4 ± 1.0 days in the propofol group (P = 0.077).Conclusions: Propofol-remifentanil anesthesia resulted in lesser increases in syndecan-1 levels compared to increases with sevoflurane-remifentanil anesthesia in patients who underwent DIEP flap reconstruction. Our results suggest that propofol-remifentanil anesthesia shows protective effects against EG damage during DIEP flap breast reconstruction in contrast to sevoflurane-remifentanil anesthesia.
The effect of 6% hydroxyethyl starch 130/0.4 preloading on the blood glucose levels in diabetic patients undergoing orthopedic surgery with spinal anesthesia: a randomized pilot study
Authors: Cho Soo Yeon , An Tae Hun , Shim Soo Bin , Lee Myungjin , Jung Ki Tae
Published: April 2023

Background: Perioperative hyperglycemia can occur in surgical patients and may increase postoperative morbidity and mortality, especially in patients with diabetes. Therefore, we conducted the present study to evaluate whether the administration of 6% hydroxyethyl starch (HES)-130/0.4 increases blood glucose levels in patients with diabetes.Methods: Forty patients undergoing lower limb surgery under spinal anesthesia were randomly allocated into two groups according to the fluids administered 20 min before spinal anesthesia (Group L, lactated Ringer’s solution; Group H, 6% HES-130/0.4). Patient characteristics, intraoperative variables, blood glucose levels, mean blood pressure (MBP), and heart rate (HR) were recorded at five time-points (0, 20, 60, 120, and 240 min).Results: A total of 39 patients were analyzed (Group L, n = 20; Group H, n = 19). The amount of intraoperative fluid was significantly higher in Group L than in Group H (718.2 ml vs. 530.0 ml, P = 0.010). There were no significant differences in the changes in blood glucose levels, HR, or MBP between the two groups (P = 0.737, P = 0.896, and P = 0.141, respectively). Serial changes in mean blood glucose levels from baseline also showed no significant differences between the groups (P = 0.764).Conclusions: There were no significant changes in blood glucose levels when lactated Ringer’s solution or 6% HES-130 was used. When compared to the lactated Ringer’s solution, no evidence that 6% HES-130/0.4 produces hyperglycemia in diabetic patients could be found. Further evaluation of larger populations is needed.
Tube or tubeless: an anesthetic strategy for upper airway surgery
Authors: Min Se-Hee , Seo Jeong Hwa
Published: April 2023

Since the patient’s airway is shared between an anesthesiologist and a surgeon, airway management during upper airway surgery can be challenging. Beyond the conventional method of general anesthesia, high-flow nasal oxygenation (HFNO) has recently been used as a key technique for tubeless anesthesia. HFNO provides humidified, heated oxygen up to 70 L/min, which promises improved oxygenation and ventilation, allowing for prolonged apneic oxygenation. In previous physiological and clinical studies, HFNO has been demonstrated that tubeless anesthesia safely provide an uninterrupted surgical field during laryngeal surgeries. Although tubeless anesthesia remains uncommon, it can be a good alternative to conventional anesthesia if an anesthesiologist and a surgeon select appropriate patients together with sufficient experience. A safe strategy for tubeless anesthesia, along with appropriate backup plans, including endotracheal intubation and high-frequency jet ventilation, should be considered for upper airway surgery.
Özel Yetenekli Öğrencilere ve Eğitimlerine Yönelik Ebeveyn Algıları*
Authors: ŞİMŞEK Furkan , ŞAHİN Murat
Published: April 2023

Bu araştırmanın amacı, Milli Eğitim Bakanlığı Özel Eğitim ve Rehberlik Hizmetleri Genel Müdürlüğüne bağlı Bilim ve Sanat Merkezlerinde özel eğitim hizmetleri çerçevesinde eğitim ve öğretim hizmeti alan özel yetenekli öğrenci velilerinin özel yetenekli öğrencilere ve eğitimlerine yönelik algılarının incelenmesi için yapılan bir fenomenoloji çalışmasıdır. Araştırma nitel araştırma yöntemi şeklinde desenlenmiştir. Literatürdeki düşünceler ortaya konularak velilerin algılarının ne yönde olduğu değerlendirilmiştir. Veriler yarı yapılandırılmış görüşme formu kullanılarak toplanmıştır. Bulgular betimsel analiz ve içerik analizi kullanılarak analiz edilmiştir. İstanbul ilindeki Ataşehir, Kartal ve Maltepe ilçeleri Bilim ve Sanat Merkezlerinde özel eğitim hizmeti alan öğrenci velilerinden 18’i araştırma grubunu oluşturmuştur. Araştırma sonucuna göre elde edilen bulgular değerlendirildiğinde velilerin özel yetenekli öğrencilere ve eğitimlerine yönelik algılarının literatürdeki düşünceler ile uyumlu olmadığı görülmektedir.
Üst Düzey Düşünme Becerilerinin Ölçülmesine Yönelik Soruların Hazırlanmasında Karşılaşılan Zorluklar ve Çözüm Önerileri: Okuduğunu Anlama*
Authors: SAYIN Ayfer , TAKIL Nazife Burcu
Published: April 2023

Bu araştırmada, Türkçe öğretmenlerinin okuma becerisi bağlamında üst düzey düşünme becerilerinin ölçülmesine yönelik soru hazırlama sürecinde karşılaştığı zorlukların belirlenmesi ve bu zorluklara çözüm önerilerinin sunulması amaçlanmıştır. Nitel araştırma yöntemlerinden durum araştırması deseninde yürütülen araştırmaya Tokat ilinde görev yapan 80 Türkçe öğretmeni katılmış ve öğretmenlerin görüşleri yarı yapılandırılmış görüşme formu ile toplanmıştır. Öğretmenlerin görüşleri içerik analizi ile kategorileştirilerek sunulmuş, öğretmenlerin üst düzey düşünme becerilerinin ölçülmesine yönelik sorulara ve soru hazırlama sürecine yönelik algıları değerlendirilmiştir. Araştırmanın sonucunda öğretmenlerin MEB tarafından “beceri temelli soru” olarak adlandırılan üst düzey düşünme becerilerinin ölçülmesine yönelik soruları genel olarak doğru bir şekilde tanımlayamadığı belirlenerek soruların özellikleri tanıtılmıştır. Öğretmenlerin soru hazırlarken seçecekleri metinlere yönelik eksik/yanlış algılarını gidermek amacıyla metin seçim kontrol listesi oluşturulmuştur. Öğretmenlerin üst düzey düşünme becerilerinin ölçülmesine yönelik soru hazırlanması sürecinde eksik/yanlış algılarını gidermek için de soru hazırlanmasına ilişkin araştırmacılar tarafından okuduğunu anlama taksonomisi sunulmuştur.
Water quality characteristics of Vanderkloof Dam and its potential for rainbow trout farming
Authors: KG Seanego  , GC Pitcher  , TA Probyn  , A Du Randt  , LM Mansfield
Published: April 2023

Vanderkloof Dam was periodically sampled between November 2014 and April 2016 for a range of water quality parameters to assess the potential for cage culture of rainbow trout, Oncorhyncus mykiss.  The dam is strongly stratified in summer and autumn, although upper water column temperatures remain relatively cool, largely <25°C. The dam is considered oligotrophic, characterised by phosphorus limitation of primary production, particularly during summer. Light is strongly attenuated in the epilimnion and heterotrophic community metabolism is observed through much of the water column. Surface nutrients are depleted through the summer with phytoplankton assemblages dominated by the green algae, Oocystis lacustris, Desmodesmus bicaudatus and Coelastrum microporum. The water column turns over during the winter and the nearly isothermal impoundment approaches 11°C. Nutrients are re-introduced into surface waters following winter mixing coincident with an increase in diatoms. The preferred environmental window for rainbow trout becomes severely contracted during the summer in that epilimnion temperatures exceed 21°C and thermocline/hypolimnion oxygen concentrations fall below 3 mg‧L−1. The coincidence of relatively high pH >9.5 could exacerbate these physiological challenges. Hydrological conditions for fish farming are most suitable in the proximity of the dam wall as opposed to further upstream. Here the hypoxic conditions that develop in the thermocline/hypolimnion during summer and autumn are less pronounced, particularly towards the southern bank, where concentrations of total suspended solids are generally <10 mg‧L−1 and water clarity is more favourable for visual feeders such as fish. Although rainbow trout may survive the adverse conditions prevalent during the summer, growth is likely to be compromised and susceptibility to disease may increase.
Canola (Brassica napus L.) water use indicators as affected by sustained deficit irrigation and plant density in central Free State, South Africa
Authors: KA Seetseng  , JH Barnard  , LD van Rensburg  , CC du Preez
Published: April 2023

In South Africa canola (Brassica napus L.) is cultivated in rotation with wheat under winter rainfall in the Western Cape Province, primarily for seed to make oil. Expansion of the crop to the other 8 provinces is proposed to reduce shortages of locally produced plant oils. At the same time, canola can serve as a rotational crop for wheat in these summer rainfall provinces. In central Free State, information on evapotranspiration and various water use indicators for canola as influenced by sustained deficit irrigation and plant density is lacking. An experiment with a line source sprinkler irrigation system was therefore conducted, comprising of full irrigation as a control with 4 sustained deficit irrigation levels (mean reduction in irrigation depth per event of 67%, 52%, 34% and 19%) and 5 plant densities (25, 50, 75, 100 and 125 plants‧m−2). Mean seasonal maximum evapotranspiration amounted to 429 mm across plant densities. Plant density did not significantly influence seasonal evapotranspiration. Reducing the irrigation depth per event by more than 20% decreased seasonal evapotranspiration by a mean 3.5 mm per percentage increase in irrigation depth. A maximum biomass water productivity of 22 kg‧ha−1‧mm−1 was measured with full irrigation and a plant density of 75 plants‧m−2. Seed water productivity amounted to a high of 11 kg‧ha−1‧mm−1 with full irrigation and a plant density of 25 plants‧m−2. A percentage reduction in irrigation depth and increase in plant density above 25 plants‧m−2 will reduce seed water productivity by 0.071 and 0.033 kg‧ha−1‧mm−1, respectively. Sustained deficit irrigation increased water use efficiency by a mean 0.5% per percentage reduction in irrigation depth per event.
Production of subsurface drip-irrigated okra under different lateral spacings and irrigation frequencies
Authors: Narender Kumar  , Sanjay Kumar  , Darshana Duhan  , Amandeep Singh  , MS Sidhpuria  , Sundeep Kumar Antil  , Ashish Kumar  , Vikas
Published: April 2023

In this study, an experiment was conducted to investigate the optimum lateral spacing and irrigation frequency for subsurface drip irrigated okra in the semi-arid region of Haryana (India). Two lateral spacings (45 cm and 60 cm) and four irrigation frequencies (daily, after 1, 2 and 3 days) were selected to grow okra in the Kharif season of 2019 and 2020. The effect on soil water dynamics, growth parameters, efficiency and yield were assessed using equal amounts of water under all the treatments on the basis of pan evaporation. The results from the study depict that the overall soil moisture decreased laterally, but increased vertically downward with the increase in the irrigation interval. On the basis of soil water dynamics, plant growth parameters, efficiency and yield of okra, it was concluded that subsurface drip irrigation with daily irrigation at 45 cm lateral spacing gives better performance than all other treatments in sandy loam soil. The present study highlights the significance of proper irrigation frequency and lateral spacing for maximum production of okra. Using these guidelines, the income of okra growers/farmers in the semi-arid region may be increased by choosing the best frequency and lateral spacing of subsurface drip irrigation.
El giro del poder mediático en la era digital. Maestría en Comunicación Estratégica Digital
Authors: Villagómez Patricia , Galán Jorge , Quishpe Espinoza Liliana , Valbuena Bedoya Orfa , Villacrez Cañar Andrea , Luciano Colángelo Pedro , Páez Cárdenas Mauricio , Álvarez Torres Carmen , Espinoza Naranjo Mauro , Cuichán Arias Armando , Andrade Salazar Wilson , Benavides Herrera Patricio , Luna Noa Jonathan , Romero Guayasamín Pablo , Pillajo Bravo Lourdes , Pavón Silva Johanna , Medranda Morales Narcisa , Minchalo Cambisaca Belén , Cañas Sigüenza Diana , Aguiar Mariño Nina
Published: April 2023

El giro del poder mediático en la era digital recoge los aportes más relevantes de los trabajos de investigación desarrollados en el Programa de Postgrado en Comunicación Estratégica Digital de la Universidad Politécnica Salesiana. Una contribución a la reflexión acerca del papel y actuación de los medios de comunicación y sus recursos digitales, más aún ante situaciones de coyuntura y conflictividad social, política o económica. El contexto histórico en el cual se enmarcan los trabajos es el periodo de protestas experimentadas en Ecuador durante octubre de 2019, a raíz de la emisión del Decreto 883 por parte del entonces Presidente de la República, Lenín Moreno, mediante el cual se incrementaba el precio de los combustibles. Las reacciones de los distintos actores sociales, organizaciones indígenas, grupos políticos y ciudadanía, no se hicieron esperar; iniciada la protesta se dio lugar a la declaratoria de estado de excepción y sus consecuencias en materia de censura previa a la información que los medios de comunicación podían divulgar acerca de los acontecimientos en curso. En este complejo escenario y ante la imperiosa necesidad de información por parte de la ciudadanía, el papel desempeñado por medios de comunicación se ubicó en el centro de la discusión, en especial los mensajes difundidos a través de sus redes sociales como parte de la lógica transmedia que caracteriza los tiempos que corren.
La loi du seuil
Authors: LOBO Carlos
Published: April 2023

Ce qui se nomme ici «loi du seuil» ne relève d'aucun droit idéal ou positif, mais lie cependant l'idée d'humanité (dans son universalité postulée) à des modalités d'usage et d'occupation de cet espace-temps global que l'on nomme «la culture». À le sillonner théoriquement, à le décrire phénoménologiquement ou le formaliser (avec Kant, Derrida, Husserl, Deleuze, ou Desanti), mais aussi à nous le figurer «poétiquement», par le biais de récits (fables, rites, contes populaires, etc.), eux-mêmes localisés sous la forme de «sous-espaces», nous sommes renvoyés à un «espace-temps total» que nos catégories et concepts ordinaires peinent à appréhender, et que l'on peut nommer «espace-temps mémorial» ou «espace de jeu». Étrangement, aucune autre caractéristique intrinsèque et stable ne se dégage si ce n'est ce fait que, à chaque fois, un espace nous sollicite et nous enjoint, singulièrement, d'y entrer. Nous comprenons de même que le franchissement du seuil tout comme notre appartenance à cet espace sont à chaque fois suspendus à la rencontre d'autres «mémoires» ou d'autres «joueurs».
Les seuils, construction et circulation de la notion et problématique épistémologique en didactique des langues étrangères
Authors: Chardenet Patrick
Published: April 2023

Du point de vue épistémologique, la notion de seuil et la question des seuils surgit dans la rupture, une posture heuristique de franchissement et d'affranchissement qui s'impose dans les sciences au XXe siècle, dans le même temps où de nouvelles disciplines surgissent de nécessités de terrain et de contraintes méthodologiques, questionnant par là-même les champs d'épistémé. En nous interrogeant sur la façon dont les notions liées de «niveau» et de «seuil» se construisent et circulent dans les discours sociaux sur les langues et au nom de la didactique des langues et des cultures, on peut comprendre le rôle qu'elles y jouent, en particulier dans une élaboration à la fois pragmatique et politique des représentations d'une langue standard quasiment fixe comme cible d'apprentissage et comme objectif d'enseignement. Il faut attendre un mouvement de reconstruction des observables dynamiques et des pratiques d'enseignement à partir de l'observation des espaces d'interlocution, de l'entre-les-langues et du lien dialogal par la convocation de la sociolinguistique, pour replacer ces notions dans une perspective dynamique, une limite illimitée.
Seuil et choix constitutionnels
Authors: Azebové Tetang Guy , Noreau Pierre
Published: April 2023

Le texte proposé exploite la notion de seuil culturel comme entre-deux, c'est-à-dire en tant que lieu de rencontre et, partant, en tant que lieu d'altérité. Il explore cette question dans le cadre d'un rappel du problème qui accompagne souvent le transfert des normes juridiques d'une communauté politique vers une autre et partant, d'un espace culturel et politique vers un autre. La question s'est notamment posée dans le cas des États africains au lendemain de leur indépendance. À l'époque, et aujourd'hui encore, la définition d'un ordre constitutionnel national exige l'importation de normes, sinon de modèles constitutionnels et politiques, inspirés d'États de droit déjà établis. Il est inévitable que ces emprunts s'accompagnent d'un transfert des référents culturels, malgré la forme supposée universelle qu'emprunte la normativité juridique. L'expérience juridique et politique des États africains démontre la difficulté qui accompagne ces greffes constitutionnelles. Des orientations et des systèmes de représentations différents, sinon opposés, se rencontrent alors au seuil du droit, tantôt inspirés par des principes et des normes constitutionnelles reconnus au plan international (et prenant la forme de standards constitutionnels), tantôt par les contraintes imposées par le contexte politique et les rapports de force nationaux, sinon par les normes juridiques et institutionnels établies localement. Le droit constitutionnel devient ainsi le lieu d'une négociation culturelle complexe, à la jonction des orientations inspirées par les États «du Nord» et réinterprétées par ceux «du Sud». Il fonde le seuil d'une discussion continue, le débat constitutionnel devient, dans ce contexte, un lieu d'altérité normative et culturelle.
Les seuils du mélodrame
Authors: Bonfil Carlos
Published: April 2023

Tout au long de l'histoire du cinéma mexicain, la narration mélodramatique a été une de ses caractéristiques les plus marquantes. C'est particulièrement vrai de la période que l'on appelle «l'Âge d'or» (1936-1955). L'objectif de notre essai est de considérer dans ce champ narratif spécifique, à partir de quelques titres emblématiques (Nosotros los pobres d'Ismael Rodriguez, Casa de vecindad de Juan Bustillo Oro et Los Fernández de Peralvillo d'Alejandro Galindo), l'importance des lieux urbains où se déroule le scénario. Tous apparaissent comme des lieux transitoires, entre détresse du déracinement et désir d'une intégration sociale, entre certitude de l'échec et espoir de la réussite; ils sont vécus comme des seuils à la fois matériels, culturels et surtout symboliques, permettant, à plus ou moins long terme, suite à une série d'épreuves ou d'initiations, d'avoir accès à une situation plus aisée voire à un nouveau statut social, ou au contraire de basculer dans une condition plus dégradante. Un de ces lieux est la vecindad, terme qui désigne au Mexique un espace résidentiel où cohabitent et se socialisent, dans une certaine promiscuité, de nombreuses familles de classes populaires, venues de l'exode rural ou du déclassement urbain. Dans ce microcosme bouillonnant s'établissent des codes sociaux et certains modèles de conduite acceptables qui à leur tour reflètent une organisation sociale et morale qui dépasse ses propres limites. Dans la vecindad -- et dans ses prolongements naturels que sont la prison ou le cabaret -- le respect des rôles génériques contraignants et des représentations dominantes de la vertu morale contribuent à garantir la coexistence pacifique de ses membres dans les limites de l'«entre-soi» et du «chez soi», tandis que l'infraction de cette norme sociale entraîne souvent l'exclusion et la dégradation, particulièrement lorsque la transgression vient des femmes. Ainsi, le cinéma mexicain propose, d'une manière parfois plus vivante que la littérature, les nombreux visages de ce comportement social ainsi qu'une interaction médiatique fascinante avec les publics populaires qui sont leur première cible.
The Relationship Between Latent Myofascial Trigger Point and Range of Motion of Knee Flexor and Extensor Muscles
Authors: Das Rajdeep , Jhajharia Birendra , Ciocan Vasile Catalin , Majumdar Indu , Sharma Arnav
Published: April 2023

The study purpose was to assess the relationship between Latent Myofascial Trigger Point and range of motion in the lower limb of athletes. A lower Pain pressure threshold (< 25 lbs/cm2) in muscles indicates the presence of a latent myofascial trigger point.
Materials and methods. Initially, the study involved 46 male Athletes (aged 20-23 years) as participants. The pain pressure threshold was measured by the pressure algometer (FPX 25 Wagner Instruments, Greenwich, CT, USA) to detect latent myofascial trigger points on the hamstring and quadriceps muscles. Out of 46 participants, 23 tested positive with a latent myofascial trigger point, and rest of them tested negative with a latent myofascial trigger point. All the participants measured knee flexor and extensor range of motion with the Kinovea software (version 0.9.5). In descriptive statistics, mean and standard deviation were used, and Pearson correlation was used to determine the relationship between the variables. The level of significance was set at 0.05.
Results. A significant correlation was found between Latent Myofascial Trigger Points and lower limb range of motion (p < 0.05), and it was also observed that the magnitude of correlation coefficient was very large (0.7–0.9).
Conclusions. Latent Myofascial Trigger Points impair sports performance by decreasing the range of motion of knee flexors and extensors. In light of this, Latent Myofascial Trigger Point should be considered a serious musculoskeletal disorder, and appropriate preventative measures should be taken by health professionals.
The Effect of Plyometrics Exercise through Agility Ladder Drill on Improving Physical Abilities of 13–15-Year-Old Volleyball Players
Authors: Pramono Harry , Rahayu Tandiyo , Yudhistira Dewangga
Published: April 2023

Study purpose. The purpose of this study was to test the plyometrics training method through agility ladder drills to increase leg muscle power, agility, and aerobic endurance in 13-15-year-old volleyball players. Materials and methods. The research method used was an experiment with a one-group pretest-posttest and pretest-posttest control group approach. The participants were 30 male volleyball players weighing 57-67 kilograms and 157-170 cm in height. Vertical jump, agility t-test, and multistage fitness test were used in this study. Data gathering methods included observation and tests, while data analysis methods included descriptive analysis, Wilcoxon, and Mann-Whitney nonparametric analysis. Results. Descriptive data revealed a difference in the mean value of the pretest and posttest of the experimental group. Furthermore, it also showed a difference in the mean value of the experimental and control groups. In the Wilcoxon test, the value of Asymp. sig(2-tailed) was 0.006<0.05, agility was  0.001<0.05, and endurance was 0.001<0.05. In the Mann-Whitney test, the value of Asymp. sig(2-tailed) was 0.416>0.05, agility was 0.00<0.05, and endurance was 0.00<0.05. Conclusions. In the experimental group, the posttest score is higher than the pretest score on power, agility, and endurance. In volleyball players aged 13-15 years, there is a significant effect, with the experimental group outperforming the control group in terms of power, agility, and endurance. As a result, one of the recommended exercises for young volleyball players is the plyometrics training method using an agility ladder drill.
Changes in Indicators of Special Physical Preparedness in Badminton Players Aged 10–11 under the Influence of Specially Selected Exercises
Authors: Shevchenko Oleg , Mulyk Kateryna , Paievskyi Volodymyr , Skaliy Aleksander , Guba Anatolii , Skaliy Tetiana , Anosova Olena
Published: April 2023

Study purpose. The study purpose was to determine changes in indicators of special physical preparedness and speed of attacking strokes in badminton players aged 10–11 under the influence of specially selected exercises. Materials and methods. The study participants were young badminton players aged 10–11 (12 boys), whose sports experience was 2-3 years. The study lasted 3 months and included: testing of special physical preparedness and assessment and analysis of the speed of attacking attacking strokes of young badminton players. Results. Analysis of the results of the study showed positive changes in the results of special physical preparedness, accuracy and speed of attacking strokes. The complex development of the speed-strength abilities of young badminton players was determined by the exercises of throwing a ball weighing 1 kg, triple long jump and jumping rope. This was manifested in the execution of attacking strokes from the place and in jumping and moving, but there was a significant increase in results in the triple jump and jumping rope. The development of speed endurance determined the 4-point center-to-center movement exercise, but the results did not change significantly over the course of the study. Accuracy indicators of attacking strokes significantly increased by an average of 2,58%. The results of the speed of attacking strokes also had a significant increase by an average of 29.41%. The use of complexes for training the accuracy of attacking strokes along with targets with a gradual complication of exercises increased the results of test exercises for accuracy and speed of execution. The indicators of the speed of attacking strokes on the left and on the right correlate with each other. The accuracy results of the right hand strokes along the line significantly correlate with right hand strokes along the diagonal and the triple long jump from a place. This indicates the connection of speed-strength abilities with the performance of attacking strokes by young badminton players. Indicators of a triple long jump from a place, jumping rope for 1 min. and throwing a ball weighing 1 kg are significantly correlated with each other, which indicates the complex development of the speed-strength abilities of young badminton players. Conclusions. The presented complexes of special preparatory exercises had a positive effect on changes in the indicators of special physical preparedness, accuracy and speed of the attacking strokes, which makes it possible to recommend them to 10–11-year-old badminton players in the training process.
5' RACE for RNA fragments with 5' phosphate v1
Authors: not provided Marta.Gaglia
Published: April 2023

This protocol will allow identification of fragments of RNA that have a 5' phosphate. It relies on ligation of an RNA adapter to the 5' end of the fragment and amplification with primers that bind the adapter and gene-specific sequences ~200 nt downstream of predicted/expected fragment end. It is adapted from protocols to map mammalian transcriptional start sites, but lacks any reaction to remove the cap. We have used it to isolate fragments generated by viral RNases.
Molecular mechanisms of cell functioning in norm and pathology
Authors: Tyukavin Alexander I. , Suchkov Sergey V.
Published: April 2023

In our study, the following are modern information about the structural and functional organization of cell membranes, the internal apparatus, as well as the cell organelle. The features of the functioning of the structural and dynamic genome are shown, including the main epigenetic mechanisms of gene expression regulation. The cell pathology section describes the main pathological processes that occur in cells after reversible and irreversible damage. The mechanisms and signaling pathways of the phenomenon, markers of cellular aging are highlighted, as well as the significance of this phenomenon in normal and pathological conditions. The main mechanisms of hypoxic and free-radical necrobiosis are described. The mechanisms, signaling pathways, and significance for the norm and pathology of two types of programmed cell death, autophagy and apoptosis, are discussed in detail. The prospect of using fundamental knowledge about the molecular mechanisms of life activity to improve the treatment of the most urgent types of pathology is shown.
An Effective Approach to Detect Liver Disorder using CNN Algorithm in Comparison with Random Forest Algorithm to Measure Accuracy
Authors: Zaheer M.M. , Nirmala P.
Published: April 2023

Aim: The ultimate aim of this work is to show the better mean accuracy of CNN algorithm in comparison with random forest algorithm on detection of liver disorder. Materials & Methods: For identification of effective approaches to detect liver disorder, the conventional neural network algorithm is used comparatively with the random forest algorithm which is an existing algorithm. For each group sample size is taken as 20 and total sample size is taken as 40. Sample size calculation was done using clincalc. com by keeping g-power at 80%, confidence interval at 95 % and threshold at 0.05 %. Result: By this innovative liver disorder detection method, it is concluded that the random forest algorithm is much lower than CNN algorithm in predicting the liver disorder. Each sample shows different accuracy values, the overall mean accuracy values shows that the CNN algorithm is having greater accuracy of 95.86% than the random forest algorithm which is having 93.88% on analysis of liver disorder approach. For CNN and random forest algorithms the statistical significance of different values is p=0.001 i.e., p<0.05 (Independent sample T-test) provided by statistical results. Conclusion: On analysis of liver disorder it is clearly known that the CNN algorithm shows better mean accuracy value then random forest algorithm. The CNN algorithm shows the accuracy of 95.86% and random forest shows the accuracy of 93.88%.
An Efficient Approach to Detect Liver Disorder Using Naive Bayes in Comparison with Decision Tree Algorithm to Measure Accuracy
Authors: Zaheer M.M. , Nirmala P.
Published: April 2023

Aim: To process an effective approach to detect liver disorder using Naive Bayes algorithm in comparison with Decision tree algorithm to measure accuracy. Methods & Materials: There are 20 samples used for both groups, where group 1 is Naive Bayes algorithm and group 2 is Decision tree algorithm which are effectively used for the identification of liver disorder approach. Result: It is a novel detection method, and it has been discovered that the Naive Bayes algorithm performs better than the Decision tree algorithm. Each sample has a distinct level of accuracy, with Naive Bayes having a mean accuracy of 94.80%, which is higher than the decision tree algorithm 92.20%. The statistical results show that the Naive Bayes and Decision tree algorithms have different statistical significance levels of p=0.01, i.e., p<.0.05 (independent sample T-test). Conclusion: On the basis of a liver disorder analysis, it is obvious that the Naive Bayes algorithm has a higher mean accuracy value than the Decision tree method. The Naive Bayes algorithm has a 94.80% accuracy rating, while decision tree has 92.20% rating. KEYWORD Naive bayes, Decision tree, Innovative liver disorder detection, Liver disorder, Machine learning, Artificial intelligence.
Comparative Study on Effectiveness of Organic Apple Juice Vinegar Over Commercially Available Vinegar Using Chemical Titration Technique for Chicken Quality Analysis
Authors: Pavantheja V. , Manikandan Dr.S.
Published: April 2023

Aim: The purpose of this research is to develop a new apple vinegar based on Podophyllum peltatum and analyze the fermentation process using a new methodology. Materials and Methods: The vinegar-making process began with the addition of Saccharomyces cerevisiae (yeast) and l (acetic bacteria) with apple. Chemical titration method is used to find out the apple juice microbial and compared to the microbial in vinegar. The microorganisms Saccharomyces cerevisiae and Acetobacter pasteurianus were found respectively. Fermentation began with fewer Saccharomyces cerevisiae and Acetobacter pasteurianus, but they were present throughout the alcoholic and acetic phases. Both microbial strains produced ethanol and acetic acid using apple as a substrate. The vinegar also produced acetate, volatile alcohols, and aldehydes. Two groups are taken with 9 sample size per group, G power 80%, coincidence intervals will be 95%. Results and Discussion: The innovative apple vinegars had an acetic acid yield of 8.1%. In the sensory evaluation, apple vinegar was well received. The technology proposed here is innovative in that it employs mixed inocula instead of separate ones (p=0.001). It also uses cell biomass instead of centrifugation at the end of the fermentative process. When compared to commercial vinegar (5%), apple vinegar has a high acetic acid concentration (8.1%). Conclusion: Reduce the working time and also be less expensive. Higher acetic acid concentration in vinegar is helpful to improve the taste of the food.
Comparison of Antibacterial Activity of Ethyl Acetate Fractions Separated from Trichoderma with Commercial Antibiotic Methicillin Against Drug-Resistant Bacteria using Minimum Inhibitory Concentration Method
Authors: Shruthi S. , Sangeetha K.
Published: April 2023

Aim: To compare the antibacterial activity of ethyl acetate fractions of Trichoderma viride against Drug-resistant bacteria. Materials and method: The ethanolic extract was made from fully grown mycelia and Trichoderma was isolated from the soil sample. Four Methicillin-Resistant Staphylococcus aureus strains were examined with the ethyl acetate extract (MRSA). The sample size was calculated using Clincalc.com, which revealed that the alpha error-threshold 0.05, the confidence interval 95%, the g-power 80%, and the enrollment ratio was 1. Groups 1 and 2 with sample size 12 each which represented drug-resistant bacteria and ethyl acetate fractions respectively. Result: The statistical Independent Sample T-Test analysis showed significant antibacterial activity against MRSA for the Trichoderma ethanolic extract with the statistical significance (p<0.05) when compared to the Susceptible bacterial strains. Conclusion: The tested ethyl acetate extract showed the MRSA at 100 μg/ml.
Efficacy on curry leaves powder consumption on blood glucose and lipid profile among type ii diabetes patients with mild elevated lipid profileexperimental study
Authors: Suganthi S.G. , Bhuvaneswari B. , Kalabarathi S.
Published: April 2023

Background: Diabetes is a chronic condition in that Type II diabetes (Formerly called as Non-Insulin Dependent) is the most prevalent, generally affecting adults, diabetes frequently reduces HDL (good) cholesterol levels while raising triglycerides and LDL (bad) cholesterol levels. Both of these factors raise the likelihood of heart disease and stroke. The Indian system of traditional medicine, Ayurveda, also uses curry leaf as a common treatment. Curry leaves can prevent several diseases, including type 2 diabetes and heart disease, because they are rich in antioxidants like beta-carotene,also rich in fibre and vitamin C. Objectives: To determine the effectiveness of curry leaves powder on reducing blood glucose and lipid profile among the clients with Type II diabetes with mild elevated lipid level in the experimental group. To compare the post-test level of blood glucose and lipid profile between the experimental and control group. Methodology: Research approach: quantitative approach, quasi experimental research design was used for 60 samples by Nonprobability purposive sampling technique. Result: on comparing the pre and post-test of blood glucose and lipid profile in relation to administering of curry leaves powder among Type II Diabetic Patients in experimental group, the percentage of reduction for fasting blood glucose is 5.72%, For Postprandial blood sugar is 6.39%, for total Cholesterol is 3.68%, for HDL the increased rate is 7.13%, for LDL the decreased percentage is 6.36%, and for Triglyceride the decrease percentage is 9.04%.
A study to assess the intervention on patients with osteoarthritis
Authors: Ramania R. , Hemavathy V.
Published: April 2023

Effectiveness of Nursing Care on Patients with Osteoarthritis .Osteoarthritis (OA) is a condition that results in joint inflammation. It’s caused by the wear and tear of cartilage, the tissue protecting the ends of your bones and joints. OA is the most common form of arthritis and is degenerative, getting worse with age. Without treatment, chronic pain from OA can lead to other complications and can significantly affect your quality of life. Assess the intervention on patients with osteoarthritis (10) was evaluated using a descriptive study methodology. A simple sampling approach was adopted in this investigation. There are three sections to the checklist. Part 1 contains data on demographic characteristics such peer group, faith, employment, learning, salary, and behaviors. Portion 2 consists of a ranking scale to keep track of the patient’s fitness. There were a total of ten variables. The observational checklist to determine the efficiency of nursing intervention of clients with osteoarthritis in part three. There are a total of ten variables. The descriptive numerical study technique to determine t-test,mean, standard deviation, % of the score in this study. Conclusion: From the intervention revealed that 6(60%) is were behind fitness complaint an no one in worthy fitness complaint beginning the assessment of clients with Osteoarthritis after comprehensive nursing care as per protocol showed that majority 7(70%) patients with Osteoarthritis client in worthy health state. A p<0.05 significant development in wellbeing, after the intervention for Osteoarthritis client.
A study to assess the effectiveness of ginger tea on symptoms of dyspepsia among adults
Authors: Cecyli C. , Soundariya S. , Jagadeeswari J. , Jency J.J. , Priyadarsini A.
Published: April 2023

Introduction: Dyspepsia is a common gastrointestinal (GI) condition around the world. Dyspepsia is a symptom complex that includes a variety of upper GI symptoms such as epigastric pain or burning, early satiety, and post-prandial fullness. Treatment with complementary and alternative medicines, particularly herbal remedies, is one option for treating dyspepsia symptoms. Objectives: The objectives of the study were to evaluate the effectiveness of ginger tea on symptoms of dyspepsia among adults Methods: A one-group pre-test and post-test research design with 30 samples who met the inclusion criteria was used. Demographic and clinical data were collected using a self-structured questionnaire. During the pre-test, a questionnaire (LDQ) was used to assess the severity of dyspepsia symptoms using an interview method. Following the pre-test, 100ml of freshly prepared ginger tea was given once a day, seven days a week, in the morning before meals. The same tool was used for the post-test after seven days of ginger tea administration. Data has been subjected to descriptive and inferential statistics Result: During the pre-test, 13(43.33 %) of the 30 samples had moderate dyspepsia, 9(30%) had severe dyspepsia, and 8(26.67%) had mild dyspepsia, whereas in the post-test, 14(46.67%) had moderate dyspepsia, 12(40%) had mild dyspepsia, and 4(13.33%) had severe dyspepsia. Ginger tea is effective when the pre-test and post-test values are compared. At the p<0.001 level, the calculated paired ‘t’ test value of t = 9.104 was found to be statistically highly significant. Demographic variables such as marital status and clinical variables such as dyspepsia duration and smoking history show a significant association with post-test dyspepsia level at p<0.05. Conclusion: According to the study findings, the overall pre-test symptom score was mild to moderate. The post-test symptom score of dyspepsia patients who were given ginger tea showed a significant reduction in symptom severity. It was concluded that ginger had a greater impact on symptom relief in dyspepsia patients than other foods.
Association between serum vitamin B12, folic acid & nitrosative stress in hypothyroidism
Authors: Kureshi N. , Aggarwal J. , Batra J.
Published: April 2023

Hypothyroidism may occur as a result of primary gland failure or insufficient thyroid gland stimulation by the hypothalamus or pituitary gland. Hypothyroidism may be associated with pernicious anemia as part of the autoimmune polyglandular endocrinopathy. Thyroid hormones (THs) influence endothelium and directly raise NO production in vascular smooth muscle cells through the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) signaling pathway. Folic acid deficiency, administration of folate antagonists such as methotrexate and carbamazepine and disturbance of methionine metabolism after hypothyroidism has been suggested as the reasons of rising in serum homocysteine levels. The following article reviewed association of serum vitamin B12, folic acid and nitrosative stress in hypothyroidism. It suggests that combination therapy with levothyroxine plus folic acid will diminish serum homocysteine level more effectively; so this treatment regimen is preferable to levothyroxine alone in hypothyroidism.
Dyslipidemia And Nephropathy In Diabetes Mellitus: A Review
Authors: Aggarwal J. , Chaudhari U.K. , Batra J. , Kumar S.S.
Published: April 2023

The prolonged increase of blood glucose give rise to complications of diabetes- premature atherosclerosis (including cardiovascular diseases and stroke), retinopathy, nephropathy and neuropathy. The lipid abnormality (dyslipidemia) associated with type 2 diabetes predominantly consists of elevated triglycerides and decreased HDL cholesterol levels. The incident of dyslipidemia in male is higher in comparison to female type 2 diabetic patients. It was also observed that type 2 diabetic patients with higher BMI has higher chance of developing dyslipidemia Diabetic nephropathy is one of the main microvascular complication of diabetes. In diabetic subjects, a major cause of morbidity and mortality is diabetic nephropathy (DN). Diabetic patients are in risk for the development of dyslipidemia and Diabetic nephropathy. Hyperglycemia causes lipid derangement and nephropathy. Elevated levels of serum cholesterol, triglycerides and lipoproteins are the main lipid derangements in diabetes which are common risk factor for coronary artery disease. It is found that elevated blood glucose levels and duration of diabetes are responsible for nephropathy and microalbuminuria. However Apo B and Lp(a) increases in the microalbuminuria and macroalbuminuria respectively.