bluuebunny/crossref_metadata_2025 huggingface dataset:
Cardiac Metastases in Patients with Neuroendocrine Tumours: Clinical Features, Therapy Outcomes, and Prognostic Implications
Authors: Liu Man , Armeni Eleni , Navalkissoor Shaunak , Davar Joseph , Sullivan Luke , Leigh Charlotte , O’Mahony Luke Furtado , Hayes Aimee , Mandair Dalvinder , Chen Jie , Caplin Martyn , Toumpanakis Christos
Published: July 2020

Background: Cardiac metastases (CM) from neuroendocrine tumours (NET) are rare; however, with the introduction of new molecular imaging modalities, such as 68Ga-DOTATATE PET-CT for NET diagnosis and re-staging, they are now identified more frequently. This study presents a single-institution experience on the NET CM characteristics, management, and prognostic implications. Methods: Between January 1998 and January 2020, 25 NET patients with CM were treated in our unit. A retrospective review of electronic records was performed. Overall survival (OS) was assessed by the Kaplan-Meier method. Cox regression models were used to evaluate the association of various clinical variables with OS. Results: The median age in the NET CM cohort was 64 years, with small intestine being the most common primary (84%). Nearly half of the patients suffered either from shortness of breath (48%) or had palpitations (12%). Peptide receptor radionuclide therapy (PRRT) was applied in more than half of the patients (64%), who had an improved trend for a longer median OS compared to those patients who did not receive PRRT (76.0 vs. 14.0 months, p = 0.196). The multivariate analysis demonstrated that concomitant skeletal or pancreatic metastases, as well as N-terminal pro-B-type natriuretic peptide (NT pro-BNP) >2 × upper limit of normal (ULN), were independent poor prognosticators. Conclusions: Clinical features of NET CM ranged from asymptomatic patients to heart failure. Concomitant bone or pancreatic metastases and NT pro-BNP levels >2 ULN predicted shorter survival time. PRRT serves as a feasible therapy with promising survival benefits; however, more data are needed.
Usefulness of the sFlt-1/PlGF (Soluble fms-Like Tyrosine Kinase-1/Placental Growth Factor) Ratio in Diagnosis or Misdiagnosis in Women With Clinical Diagnosis of Preeclampsia
Authors: Leaños-Miranda Alfredo , Graciela Nolasco-Leaños Ana , Ismael Carrillo-Juárez Reyes , José Molina-Pérez Carlos , Janet Sillas-Pardo Liliana , Manuel Jiménez-Trejo Luis , Isordia-Salas Irma , Leticia Ramírez-Valenzuela Karla
Published: July 2020

Preeclampsia is characterized by angiogenic imbalance (AI), sFlt-1 (soluble fms-like tyrosine kinase-1)/PlGF (placental growth factor) is useful for its diagnosis and prediction of adverse outcomes, but the relationship among the degrees of AI as assessed by this ratio with the correct diagnosis, clinical characteristics, and outcomes in women with clinical diagnosis of preeclampsia are unclear. We studied 810 women with clinical diagnosis of preeclampsia. Patients were divided into 3 groups based on their degree of AI, evaluated by the sFlt-1/PlGF ratio: no AI (≤38), mild AI (>38–<85), and severe AI (≥85). Patients with no AI were more likely to have comorbidities and false significant proteinuria compared with patients with mild and severe AI (
P
<0.001). The rates of preterm delivery, delivery within 14 days, and small-for-gestational-age infant were higher among patients with severe AI than in patients with no and mild AI (
P
<0.001) and in patients with mild AI that in those with no AI (
P
≤0.01). The occurrence of any adverse maternal outcome (HELLP syndrome, elevated liver enzymes, thrombocytopenia, placental abruption, acute kidney injury) was only present in patients with severe AI. Interestingly, the frequency of misdiagnosis of preeclampsia was progressively lower as the degrees of AI increased (no AI: 100%, mild AI: 88.2%, and severe AI: 15.6%). We concluded that in women with clinical diagnosis of preeclampsia, severe AI is characterized by high frequency of true preeclampsia and preeclampsia-related adverse outcomes, in contrast, no and mild AI, are characterized by unnecessary early deliveries, often due to misdiagnosis.
Cardio‐Oncology in the Era of the COVID‐19 Pandemic and Beyond
Authors: Addison Daniel , Campbell Courtney M. , Guha Avirup , Ghosh Arjun K. , Dent Susan F. , Jneid Hani
Published: July 2020

Coronavirus disease 2019 (COVID‐19) has emerged as a global pandemic and public health crisis. Increasing waves of intermittent infectious outbreaks have dramatically influenced care among broad populations. Over the past 2 decades, there has been a rapid increase in cancer survival, with >400 000 new survivors each year. The increasingly common presence of cardiovascular disease in patients during or after cancer treatment led to the rapid growth of the field of cardio‐oncology with a mandate of identifying, treating, and preventing the various forms of cardiovascular disease seen among this population. This review evaluates the implications of the pandemic on the practice and study of cardio‐oncology. The evolving understanding of the relationship between comorbid disease and clinical outcomes among this population is assessed. With the impetus of the pandemic, cardio‐oncology can be deliberate in embracing changes to cardiac screening, monitoring, and intervention during oncology care. Bridging 2 specialties, consideration of the lessons learned in cancer and cardiovascular may pivotally inform ongoing therapeutic efforts. Further, the development of multicenter registries focused on understanding and optimizing outcomes among these patients should be considered. Together, these insights may critically inform strategies for the care of cardio‐oncology patients in future phases of the COVID‐19 pandemic and beyond.
Morpho-molecular analysis reveals Appendiculella viticis sp. nov. (Meliolaceae)

Authors: MARASINGHE DIANA S. , BOONMEE SARANYAPHAT , HYDE KEVIN D. , XIE NING , HONGSANAN SINANG
Published: July 2020

A novel species, Appendiculella viticis, was collected on freshly fallen leaves of Vitex canescens (Lamiaceae) in Chiang Rai, Thailand. This species is unique in having vertically striate, conoid cells, without larviform appendages and fusiform to ellipsoidal, guttulate ascospores. Morphological comparison and phylogenetic analysis of combined LSU and ITS sequence data provide evidence that the species is novel. Morphological comparisons of Appendiculella species are provided. The molecular data provides evidence to support the distinctness of Appendiculella.
Gastrodia khangii, a new synonym and new record of Gastrodia bambu (Orchidaceae) in Vietnam

Authors: METUSALA DESTARIO
Published: July 2020

Gastrodia khangii (Orchidaceae) was described in 2018 as a new and endemic holomycotrophic species from northern Vietnam. After careful examination and morphological comparisons, it has been concluded that G. khangii is matched with the description of G. bambu from Indonesia. Thus, G. khangii is proposed here as a synonym of G. bambu and at the same time as new record of G. bambu in Vietnam.
A synopsis of the moss family Splachnaceae (Bryophyta) in Brazil

Authors: PERALTA DENILSON FERNANDES , CARMO DIMAS MARCHI DO
Published: July 2020

We recognize four genera and six species of Splachnaceae in Brazil. Tetraplodon itatiaiae Müll.Hal. is proposed as a new synonym of Tetraplodon mnioides (Hedw) Bruch & Schimp., and Tetraplodon tomentosus Sehnem new synonym of Leptodontium capituligerum Müll.Hal. Three species are recognized as endemic: Moseniella ulei (Müll.Hal. ex Broth.) A. Kop., M. brasiliensis Broth., and Tayloria arenaria (Müll.Hal.) Broth. The species Tayloria scabriseta (Hook.) Mitt. is a new record for the country. We provide identification keys, comments, and diagnostic illustrations, as well as comments on their conservation status.
Combining Emergent Constraints for Climate Sensitivity
Authors: Bretherton Christopher S. , Caldwell Peter M.
Published: July 2020

A method is proposed for combining information from several emergent constraints into a probabilistic estimate for a climate sensitivity proxy Y such as equilibrium climate sensitivity (ECS). The method is based on fitting a multivariate Gaussian PDF for Y and the emergent constraints using an ensemble of global climate models (GCMs); it can be viewed as a form of multiple linear regression of Y on the constraints. The method accounts for uncertainties in sampling this multidimensional PDF with a small number of models, for observational uncertainties in the constraints, and for overconfidence about the correlation of the constraints with the climate sensitivity. Its general form (Method C) accounts for correlations between the constraints. Method C becomes less robust when some constraints are too strongly related to each other; this can be mitigated using regularization approaches such as ridge regression. An illuminating special case, Method U, neglects any correlations between constraints except through their mutual relationship to the climate proxy; it is more robust to small GCM sample size and is appealingly interpretable. These methods are applied to ECS and the climate feedback parameter using a previously published set of 11 possible emergent constraints derived from climate models in the Coupled Model Intercomparison Project (CMIP). The ±2σ posterior range of ECS for Method C with no overconfidence adjustment is 4.3 ± 0.7 K. For Method U with a large overconfidence adjustment, it is 4.0 ± 1.3 K. This study adds confidence to past findings that most constraints predict higher climate sensitivity than the CMIP mean.
Evaluation on the Capability of Revealing Ocean Swells from Sentinel-1A Wave Spectra Measurements
Authors: Wang Xuan , Husson Romain , Jiang Haoyu , Chen Ge , Gao Guoping
Published: July 2020

Wave measurements retrieved bySentinel-1Alevel-2 ocean (OCN) products are sensitive to swells other than wind seas, and are considered to provide a finer resolution of ocean swells. To assess the capability of swell retrieval globally, OCN products are validated against WAVEWATCH III (WW3) wave spectra for two available incidence angles [“wave mode” (WV); WV1: 23°; WV2: 36°], focused on the integral wave parameters and most energetic wave system ofSentinel-1A. The wave parameter difference betweenSentinel-1Aand WW3 along antenna look angles for WV1 demonstrates the obvious impact of the nonlinearity influence in the azimuth direction, resulting in an unrealistically high wave height at the low wave frequency, and the spurious split of wave systems in the range direction, due to the vanishing of velocity bunching modulation. WV2 is less pronounced in these two aspects, but tends to shift wave energy to a higher wave frequency in the range direction. The inside discrepancy of wave energy has two noticeable features: the difference in peak wavelengths in the wave spectrum is positively clustered in the azimuth direction and negatively clustered in the range direction; some of the most energetic partitions derived fromSentinel-1Aare difficult to assign to any wave systems in WW3. This phenomenon could be related to wind-wave coupling as the azimuth cutoff/WW3 peak wavelength is confined to a ratio below 0.5 for the negative difference betweenSentinel-1Aand WW3 peak wavelengths and the spectral distance of most energetic wave system inSentinel-1Ahighly resembles “swell pools.”
Assessment of tacrolimus and creatinine concentration collected using Mitra microsampling devices
Authors: Marshall David J , Kim Jon Jin , Brand Sarah , Bryne Catherine , Keevil Brian G
Published: July 2020

Background

Current practice requires regular venous blood samples for monitoring of tacrolimus concentrations post renal transplant requiring regular hospital visits. Mitra devices use volumetric absorptive microsampling technology and absorb a fixed amount of blood (10  μL) from a capillary blood sample. They are a viable volumetric alternative to dried blood spots and are able to be posted to the laboratory for analysis.

Objective

The aim was to develop and validate liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays for tacrolimus and creatinine analysis using Mitra devices. The usefulness of this approach was assessed in renal transplant patients routinely monitored for tacrolimus and creatinine.

Method

Routine tacrolimus samples were used to assess the utility and reliability of Mitra sampling. Shared sample preparation for both tacrolimus and creatinine was carried out in a 96-deep well plate; mass spectrometric analysis was then undertaken for tacrolimus followed by re-injection for creatinine analysis.

Results

Comparison of 131 Mitra samples with a routine LC-MS/MS assay for tacrolimus showed a minimal bias –5.6% (95% CI –8.5 to –2.7%). Comparison of 135 serum and Mitra samples for creatinine using a fully validated LC-MS/MS assay showed a bias –6.5% (95% CI –8.5 to –4.5%).

Discussion

We have developed assays for tacrolimus and creatinine on fingerprick blood using the Mitra device and believe this approach provides a viable alternative to repeated venepuncture for therapeutic drug monitoring. This method could open up the opportunity for patients to perform tacrolimus and kidney function monitoring at home.
On the Century of Peacemaking at the 1919 Treaty of Versailles: Looking Back to Look Ahead
Authors: Desai Bharat H. , Desai Jay B.
Published: July 2020

This study seeks to make a modest effort to look back at the marathon peacemaking ushered into by the Treaty of Versailles, during 1919–1922 periods, after Armistice was signed on 11 November 1918, bringing to an end the First World War. It has sought to place under scanner the said arduous process of peacemaking, resulting in an imposing corpus of five treaties comprising 1914 articles with Germany and its four other allies (Austria, Bulgaria, Hungary and Turkey). It presents an interesting role of the principal peacemakers therein along with the advent of the era of ‘organizing’ through the League of Nations and other entities such as International Labour Office and Permanent Court of International Justice. Now, at the distance of 101 years from the main event that heralded new milestones in international law and international relations, we have sought to make sense of it so as to deduce lessons to look ahead for our better world. Knowing well that alike human beings, any peacemaking cannot be flawless, it has been our endeavour to provide an objective understanding of the great peacemaking, its aftermath (1919–1939) and its relevance for the United Nations–led world order in the 21st century.
Rigid polyurethane foams modified with borate and oxamide groups – Preparation and properties
Authors: Zarzyka Iwona , Pacześniak Tomasz , Frącz Wiesław
Published: July 2020

In this work the results of the research on modification of rigid polyurethane foams properties by new polyols with borate and oxamide groups have been presented. Propylene glycols — the products of hydroxyalkylation of N,N′-bis(2-hydroxypropyl)oxamide bis(dihydrogenborate) by excess of propylene carbonate (PC) was used as a polyol component. The new polyols have been foamed using polymeric 4,4′-diphenylmethane diisocyanate, water and triethylamine. The modification of the foam structure by oxamide and borate groups guarantees their low water uptake, very good heat-insulating properties, good dimension stability and decreases their flammability, and does not worsen their mechanical properties and thermal stability.
Hybrid epoxy composites made from treated curauá fibres and organophilic clay
Authors: del Pino Gilberto García , Bezazi Abderrezak , Boumediri Haithem , Kieling Antonio Claudio , Silva Cláudia Cândida , Dehaini Jamile , Rivera Jose Luis Valin , Valenzuela Maria das Graças da Silva , Díaz Francisco Rolando Valenzuela , Panzera Túlio Hallak
Published: July 2020

This work evaluates an epoxy composite reinforced with curauá fibres and/or organophilic clay. Epoxy polymers reinforced with nano-clays are also assessed. Composites are manufactured by cold pressing using fibres in pristine and treated conditions. Three levels of the factors NaOH solution (2.5, 5 and 10%) and immersion time (2, 4 and 10 hours) are investigated. Nano-clays are incorporated at the levels of 2.5, 5 and 10 wt.%. The morphology and crystallinity of the treated fibres are evaluated by scanning electron microscopy and X-ray diffraction, respectively. Tensile, three-point bending and impact tests are performed to characterise the composites. Tensile strength, flexural strength and impact resistance are increased by 24%, 44% and 47%, respectively, when compared to untreated fibre composites. The highest tensile and flexural strengths are achieved by hybrid composites containing 5 wt.% of nano-clay and 20 wt.% of curauá fibres treated with 5% NaOH for 4 hours. In contrast, the highest tensile modulus is achieved when hybrid composites are made from untreated fibres and 10 wt.% of nanoparticles. The highest impact resistance is obtained by curauá composites, without particles, composed of fibres treated with 5% NaOH for 4 hours. The inclusion of nano-clay leads to reduced impact resistance values.
Dedicated care pathways in Italian hospital emergency rooms for women who are victims of violence and abuse: Italian National Guidelines (DPCM 24.11.2017 – G.U. n. 24 issued 30.01.2018)
Authors: De Matteis Alessandra , Maiese Aniello , Chinotti Franceska , Bolino Giorgio
Published: July 2020

Gender-based violence affects one third of women globally with death the ultimate consequence after repeated violence. Government intervention is imperative. This article focuses on recent Italian legislation that provides a framework to assist victims of violence in Italian Emergency Rooms.
Couples Facing Skin Cancer in Old Age: A Dyadic Investigation of Partner Support and Quality of Life
Authors: Butner-Kozimor L. Michelle , Savla Jyoti
Published: July 2020

This study investigated perceived support received by partners and its association with quality of life (QOL) in older couples facing skin cancer. Thirty couples ( n = 60; M Age = 70) in which one partner had a skin cancer diagnosis (PwSC) completed either online or paper surveys about their skin cancer diagnosis, perceived partner support, and overall QOL. Actor–partner interdependence models revealed that when PwSCs reported overprotection from their healthy partners (HPs), they were more likely to report lower QOL. Protective buffering received by HPs was negatively associated with their QOL as well as their PwSCs QOL. Active engagement support, however, was not associated with either partner’s QOL. While couples may use all three styles of relationship-focused support, protective buffering and overprotection affected each partner’s QOL. Implications of the study findings for interventions for couples facing illnesses like skin cancer are discussed.
A sensorless angular displacement measurement method for rotational oscillation generation in biomedical applications with Ros-Drill©
Authors: Nak Handan , Ergenc Ali Fuat
Published: July 2020

This paper presents a novel measurement method for angular displacement of an oscillation-assisted micro drill device, Ros-Drill©. The device is driven with a brushless dc motor (BLDC) which is desired to track a sinusoidal position reference. The measurement method is based on the principle of monitoring the back-emf voltage that is induced on the non-fed winding of the brushless motor. It offers sensorless analog measurement of the angular displacement of the oscillatory motion which is not possible with optical encoders. The measurement methodology and control algorithms are implemented utilizing a digital signal processor. Experiments reveal that the method is feasible for measuring angular displacements of rotational oscillations during cellular piercing operations. Furthermore, it presents fair performance for frequencies up to 1000 Hz and provides early diagnosis for a potential malfunction of the micro drill.
Beyond Self-Control: Mechanisms of Hedonic Goal Pursuit and Its Relevance for Well-Being
Authors: Bernecker Katharina , Becker Daniela
Published: July 2020

Self-control helps to align behavior with long-term goals (e.g., exercising to stay fit) and shield it from conflicting hedonic goals (e.g., relaxing). Decades of research have shown that self-control is associated with numerous positive outcomes, such as well-being. In the present article, we argue that hedonic goal pursuit is equally important for well-being, and that conflicting long-term goals can undermine it in the form of intrusive thoughts. In Study 1, we developed a measure of trait hedonic capacity, which captures people’s success in hedonic goal pursuit and the occurrence of intrusive thoughts. In Studies 2A and 2B, people’s trait hedonic capacity relates positively to well-being. Study 3 confirms intrusive thoughts as major impeding mechanism of hedonic success. Studies 4 and 5 demonstrate that trait hedonic capacity predicts successful hedonic goal pursuit in everyday life. We conclude that hedonic goal pursuit represents a largely neglected but adaptive aspect of self-regulation.
Parenting Behaviors as Moderators of the Relationship between Immigrant Status and Alcohol Use among Adolescents in Israel
Authors: Walsh Sophie D. , Kolobov Tanya , Harel-Fisch Yossi
Published: July 2020

Adolescent alcohol use is a subject of concern. Despite research showing an association between parenting behaviors and alcohol use, scarce research has examined whether associations are similar across immigrant status. This question is relevant given that immigration can disrupt parent–adolescent relations. The aim of the current study was to examine the moderating role of parenting behaviors (support, parental knowledge, and communication) on the association between immigrant status and alcohol use (drunkenness and heavy episodic drinking). The study included representative samples of first- and second-generation immigrant adolescents from the Former Soviet Union (FSU; N = 1,167) and Ethiopia ( N = 385), and non-immigrant ( N = 6,669) adolescents in Israel. Non-immigrant adolescents reported higher levels of parenting behaviors and lower levels of alcohol use than immigrant adolescents. Parenting behaviors were negatively associated with alcohol use, but there were no interactions between parenting behaviors and immigrant status. However, differences in parenting behaviors partly explained differences in alcohol use across groups.
L2 processing of filler-gap dependencies: Attenuated effects of naturalistic L2 exposure in a multilingual setting
Authors: Berghoff Robyn
Published: July 2020

In the online processing of long-distance wh-dependencies, native speakers have been found to make use of intermediate syntactic gaps, which has the effect of facilitating dependency resolution. This strategy has also been observed in second language (L2) speakers living in an L2 immersion context, but not in classroom L2 learners. This research note investigates whether there is evidence of use of the intermediate gap among L2 speakers that have received considerable naturalistic exposure to the L2 from a young age, but do not live in a standard immersion context. Two groups of participants, one L1 English and one L1 Afrikaans–L2 English, completed a self-paced reading task involving English sentences containing long-distance wh-dependencies. The data were analysed using Bayesian regression. The results indicate that the intermediate gap facilitated dependency resolution in the L1 English group but not in the L2 group. Increased L2 exposure seemed to increase sensitivity to the intermediate gap among the L2 speakers, but was not associated with faster dependency resolution. The findings suggest that although non-immersive L2 experience affects L2 processing of abstract grammatical cues, it may be less effective than fully immersive experience in engendering nativelike processing of long-distance wh-dependencies.
Iliac vein stenting is a safe and effective treatment for iliac vein compression syndrome: A systematic review of Chinese data
Authors: Wang Shiyue , He Yuchen , Xin Shijie , Zhang Jian
Published: July 2020

Objectives

This study was a systematic review of available data from China, and our aim was to evaluate the safety and efficacy of stenting in iliac vein compression syndrome.

Methods

We searched the PubMed, National Knowledge Infrastructure, Chongqing Weipu Information Company, and Cochrane Central Register for Controlled Trials databases, and key references.

Results

Twelve studies were included (nine retrospective analyses, two retrospective case series studies, and one prospective cohort study) involving 2292 patients and 1897 stented limbs. The overall primary patency rates ranged from 81.8% to 100%. Studies showed significant improvements in patients’ symptoms, and ulcer healing rates ranged from 71.4% to 100% in stented limbs. The incidence of severe complications ranged from 0 to 16.8%.

Conclusions

For Chinese patients with iliac vein compression syndrome, stenting provided significant efficacy regarding favorable patency rates, symptom relief, and complications. However, the quality of evidence to support the use of iliac vein stenting to treat iliac vein compression syndrome is currently weak, especially for Chinese patients.
Music, body movement, and dance intervention program for children with developmental coordination disorder
Authors: Díaz-Pérez Ariadna , Vicente-Nicolás Gregorio , Valero-García Ana Vanesa
Published: July 2020

The aim of this study is to evaluate the effectiveness of an intervention program, based on music, movement, and dance, aimed at improving motor skills in children at risk of developmental coordination disorder (DCD). Participants comprised 70 primary school children (47 boys/23 girls) aged between 6 and 8 years. Participants were given the Spanish adaptation of the Movement Assessment Battery for Children–Second Edition (MABC-2) to identify difficulties and initially classify into three groups: a group of 17 at risk of DCD who participated in the intervention program (Experimental Group), a group of 18 at risk of DCD who did not participate (Control Group with Risk) and a group of 35 children, with scores higher than the cutoff point (Control Group without Risk). The results show a significant improvement in the motor skills of children who participated in the intervention program, while those in the Control Group showed no significant changes in the second evaluation compared with the first. Likewise, it could be affirmed that this intervention based on group activities involving music, movement, and dance is a very successful blend for motor improvement in children with coordination problems, due to the combination of cognitive stimulation areas and techniques.
A Novel Use of Topical Ketamine for the Treatment of Oral Pemphigus: A Case Report
Authors: Higgins Elizabeth A. , West Julia Arana
Published: July 2020

Background:

Paraneoplastic pemphigus (PNP) is a rare autoimmune blistering disease often associated with lymphoproliferative disorders. PNP causes hemorrhagic stomatitis of the lips, tongue, and cheeks which can be painful and difficult to treat.

Case History:

A 54-year-old man was referred to our hospital for treatment of Stage IV lymphoma and paraneoplastic pemphigus. Due to pain from oral stomatitis, he required a gastrostomy tube for delivery of nutritional tube feeds. He was placed on steroids and received both lidocaine mouthwash and opioids, but his pain persisted.

Case Management and Outcome:

A palliative care consult was obtained for management of his pain. The palliative team recommended topical ketamine for the treatment of the painful lip lesions. The patient felt immediate relief with the application of ketamine and his pain level was reduced to a 5/10. The following day, his pain was 0/10. Five days later, the opioids were discontinued and the pain relief continued.

Conclusion:

Painful stomatitis from PNP may be refractory to standard treatment. We found that the application of topical ketamine was very effective in this patient with hemorrhagic stomatitis from PNP.
Differences in Executive Functions in Minors Suffering Physical Abuse and Neglect
Authors: Moreno-Manso Juan Manuel , García-Baamonde Mª Elena , de la Rosa Murillo María , Blázquez-Alonso Macarena , Guerrero-Barona Eloísa , García-Gómez Andrés
Published: July 2020

This research analyzes the executive functions in minors between 7 and 16 years of age who have suffered physical abuse and neglect, as well as minors in residential care centers with other measures of protection. Most studies focus on the neurobiological consequences of the abuse, and mainly at an early age. However, there are very few studies that analyze the executive functions of victims of child abuse, while also taking into account the type of abuse suffered. This study aims to identify whether the consequences of child abuse for the executive functions are different for those minors who have been victims of physical abuse and neglect, in comparison with minors with other protective measures. The participants were 44 minors who had suffered child abuse and 24 minors with other protective measures, distinct from abuse. Three neuropsychological tests were used: (a) the Five Digits Test (FDT), (b) the Behavioral Assessment of the Dysexecutive Syndrome in Children (BADS-C), and (c) the Wechsler Intelligence Scale for Children–V (WISC-V). The results showed difficulties in those minors who had been victim of physical abuse and neglect, in their cognitive flexibility capabilities, inhibitory control, the ability to take decisions, the ability to organize and plan their behavior, control of emotions, and attention control. It was the minors who were victims of physical neglect that showed the greatest difficulties in their executive functions. The results of the study will permit us to design an educational intervention in the residential care centers that can encourage advances in the affected areas through the setting up of different strategies to favor the stimulation, reinforcement, and rehabilitation of the executive functions.
Chronic Pain Personification Following Child Abuse: The Imprinted Experience of Child Abuse in Later Chronic Pain
Authors: Tsur Noga
Published: July 2020

Child abuse has been shown to increase the risk for chronic pain. The illness personification theory implies that individuals tend to ascribe humanlike characteristics to chronic pain, and that this personification is embedded in the way they cope with their chronic condition. Recent findings demonstrate that individuals who experienced interpersonal violence tend to personify chronic pain in a way that resonates with past abusive experience. Although findings prevail to the link between trauma and the experience of the body, the personification of chronic pain among individuals who experienced child abuse has not been examined before. This article includes two studies that tested whether child abuse is implicated in abusive chronic pain personification in a young adult female sample (Study 1) and among females who experienced child abuse (Study 2). In both studies, self-report measures of child abuse, posttraumatic stress (PTS) symptoms, complex posttraumatic symptoms (disturbances of self-organization [DSO]), and abusive chronic pain personification were administered. Structural equation modeling was utilized to assess the hypotheses. The findings of the two studies showed a significant association between child abuse and pain personification. Whereas PTS symptoms did not mediate this link (Study 1), DSO symptoms mediated this association (Study 2). The findings of these studies support the understanding that the experience of interpersonal violence is engraved in the experience of the body, as reflected in abusive chronic pain personification. Disturbances in self-organization seem to underlie this process, thus pertaining to the link between the experience of the body, self, and interpersonal trauma.
Exploring Sex Differences in the Effectiveness of Telehealth-Based Health Coaching in Weight Management in an Employee Population
Authors: Johnson Kelly E. , Alencar Michelle K. , Miller Brian , Gutierrez Elizabeth , Dionicio Patricia
Published: July 2020

Purpose:

To explore a telehealth-based lifestyle therapeutics (THBC) program on weight loss (WL) and program satisfaction in an employer population.

Design:

This study was a collaboration between inHealth Lifestyle Therapeutics and a large national employer group including 685 participants (296 women [64% obese] and 389 men [62% obese]).

Measures:

Percent WL and subjective rating (Perceived Program Value measured by a questionnaire) were assessed.

Intervention:

Average number of visits was 3.1 ± 0.4; each visit ranged between 20 and 45 minutes.

Analysis:

This study utilized a 2 × 2 block design using analysis of variance techniques based on sex (male and female) and initial body mass index (BMI) category (overweight and obese) tested at P ≤ .05.

Results:

There was no statistical difference in %WL between by sex ( F1,681 = 0.398, P = .528) nor an interaction between sex and BMI ( F1,681 = 0.809, P = .369). There was a statistically significant difference in %WL from pre to post program across initial BMI category ( F1,681 = 13.707, P ≤ .001) with obese participants losing an average of 1.1% (0.5%-1.6%) more than overweight participants (overweight 2.5% [2.1%-3.0%] vs obese 3.6% [3.2%-3.9%]). Obese participants were 1.15 (1.07-1.25) times more likely to lose weight compared to overweight participants. Analysis of variance power analysis indicated sufficient power on minimum factor combination n = 106 ( Effect Size = 0.282).

Conclusion:

Results support the efficacy THBC in supporting WL with no reported differences between men and women, while having a high perceived value for employee participants.
Back to the Sicilian Landing Sites: Exploring a Borderland through a Refugee Gaze
Authors: Queirolo Palmas Luca
Published: July 2020

This article is based on a shared ethnographic experience centered on a trip back to a crucial landing site in Sicily. Searching for the evocative and emotional dimension of a border zone, the research follows a refugee, who is now living within the institutional reception system in Northern Italy, wandering and rediscovering the moment of his arrival three years after having been rescued. The dialogue that emerged from this experience focuses on the following aspects: the relationship between death at sea and the willingness to remember and give testimony, the security turn in the management of programmed landings, the production of the sea smuggler as a comfortable public enemy and scapegoat, and the camp as a device of segregation rather than hospitality. Through these four aspects, the article explores the critical possibilities of a refugee gaze, trying to explore the border from a different perspective from that of the state’s thought on migration.
Entrepreneurship in Small Cities: Evidence From U.S. Micropolitan Areas
Authors: Liu Shiqin , Qian Haifeng , Haynes Kingsley E.
Published: July 2020

This article presents the spatial patterns of general and high-tech start-up rates and explores regional factors associated with entrepreneurship in U.S. micropolitan areas. Regression results show that general entrepreneurship in these small cities is predicted by population growth, the middle-age population group, the presence of small businesses, and natural amenities. Additionally, high-tech start-up activities are positively associated with human capital, creative knowledge (instead of technological knowledge), high-tech clustering, and proximity to a large metropolitan area. These findings are compared with the patterns in larger metropolitan areas. This research sheds light on local entrepreneurship policy in the small-city context.
Study on micro cutting fundamentals considering the cutting edge radius and the workpiece material in micro end milling
Authors: Li Yang , Cheng Xiang , Ling Siying , Zheng Guangming , Liu Huanbao , Wang Fei
Published: July 2020

Previous studies found that the peripheral cutting edge and end cutting edge in micro end milling had different cutting phenomena considering the size effect in micro cutting processes. This paper is a further study on this point considering different workpiece materials and cutting edge radii. Finite element simulations have been conducted to determine the minimum undeformed chip thickness (MUCT) by the chip morphology and the results are verified by micromilling experiments. Both the simulations and experiments show that the MUCT of the peripheral cutting edge and the end cutting edge are different even if the cutting edge radii remain unchanged. The MUCT is directly proportional to the cutting edge radius. Material properties also have some effects on the MUCT of the peripheral cutting edge. But it has limited effects on that of the end cutting edge. The results indicate that the feed engagement other than the axial depth of cut should be carefully selected in micro end milling when considering different workpiece materials.
Study on integrated control for supersonic inlet and turbofan engine model
Authors: Chen Haoying , Zhang Haibo , Du Yao , Zheng Qiangang
Published: July 2020

Considering the supersonic inlet model with normal shock position feedback, the integrated control method of inlet and turbofan engine is studied. The integrated model includes the supersonic inlet model and the component level model of engine. Combining the relationship between the normal shock position and the total pressure recovery coefficient, the supersonic inlet and engine model is constructed. On the basis of this model, the normal shock position closed-loop control simulation is carried out, which shows that the normal shock position matching point could be stabilized near the optimal value while restraining the inlet stream disturbance. Furthermore, based on the H∞ control algorithm, an inlet and engine integrated control is designed to control the installation thrust and turbine pressure ratio with fuel, nozzle throat area, and normal shock position as control variables. The simulation results show that the response time of the integrated control is faster than the independent control. The integrated control has stronger ability to restrain the atmospheric disturbance, which could ensure the stable and reliable operation of the propulsion system.
A model reference adaptive sliding mode control for the position control of permanent magnet synchronous motor
Authors: Jiang Junfeng , Zhou Xiaojun , Zhao Wei , Li Wei
Published: July 2020

A model reference adaptive sliding mode control for the position control of the permanent magnet synchronous motor is developed in this article. First of all, a fast sliding surface is designed to achieve faster convergence than the ordinary sliding mode control. Then, the adaptive laws are developed to make the control parameters, especially the switching gain, updated online. Therefore, the chattering can be reduced effectively and the disturbance can be rejected well. Finally, a reference model which produces an exponential decay curve is applied for the position error to follow. Thus, not only fast error convergence can be guaranteed, but also the dynamic process of the system response can be controlled easily by modifying the decay rate of the reference model. The proposed model reference adaptive sliding mode control scheme combines the advantages of the sliding mode control and the model reference adaptive control. Simulation and experimental results reveal that faster and more accurate performance with smoother control signal and better robustness is obtained compared with other methods. Also, the model reference adaptive sliding mode control method can maintain good performance when the system inertia or the position reference varies in a wide range.
Judicial impartiality, decorative comparative law and the Human Rights Court: ECtHR, Alexandru Marian Iancu v. Romania, Application No. 60858/15
Authors: Husa Jaakko
Published: July 2020

This case-note analyses the case of Alexandru Marian Iancu v. Romania, decided by the European Court of Human Rights in February 2020. The comment addresses two essential issues involved. The first issue concerns potential partiality of a judge who has been involved in overlapping proceedings. The second issue concerns the judicial method the Court uses in its reasoning. The note explains the background to the judgment, summarizing the facts leading to the judgment and the human rights issues before the Court. Then the proceedings before the Court and the Court’s decision are reviewed, before commenting on the judgment’s key points of significance for human rights law and use of comparative law as a part of human rights reasoning. The critical focus is on the comparative approach deployed by the Court.
Modafinil-induced psychosis in a patient with attention deficit hyperactivity disorder
Authors: Flavell Joshua
Published: July 2020

Modafinil is a wakefulness-promoting agent that is known to be used off-label as a cognitive enhancer and for the treatment of attention deficit hyperactivity disorder (ADHD).1 There are increasing case reports of Modafinil-induced psychosis; however, this is the first to report a patient with ADHD to develop psychosis from Modafinil use.
Teaching Philosophy Statements
Authors: Laundon Melinda , Cathcart Abby , Greer Dominique A.
Published: July 2020

Teaching philosophy statements articulate educators’ beliefs about what makes learning happen. They can be powerful tools in identifying assumptions about teaching, articulating our values as educators, and connecting to a community within and across disciplines. Teaching philosophy statements are often an integral part of job applications, promotion and tenure processes, teaching development, and teaching awards. By developing a philosophy and discussing it with colleagues, educators can improve their practice through the process of reflection, dialogue, and engagement with scholarship of learning and teaching. The recipients of the 2020 JME Lasting Impact Award are companion articles “Philosophy rediscovered: Exploring the connections between teaching philosophies, educational philosophies, and philosophy” and “Finding our roots: An exercise for creating a personal teaching philosophy statement” by Beatty et al. These articles have had a profound and sustained impact on management education and other disciplines by furthering understandings of teaching philosophies and their connection to effective teaching and learning. Analysis of subsequent teaching philosophy statement research identifies three strands of inquiry: how to develop a teaching philosophy, the role of teaching philosophies in graduate education, and the relationship between teaching philosophies and continuous professional development. The impact of the papers and areas for future research are canvassed.
Nurse Practitioner Involvement in Medicare Accountable Care Organizations
Authors: Huang Nicole , Raji Mukaila , Lin Yu-Li , Chou Lin-Na , Kuo Yong-Fang
Published: July 2020

The objective was to examine trend and care quality outcomes associated with nurse practitioner (NP) involvement in Accountable Care Organizations (ACOs) via a cross-sectional study of 521 Medicare Shared Savings Program ACOs during 2014 to 2016. Data include ACO provider/beneficiary files, Medicare claims, and ACO performance data with a focus on Medicare beneficiaries with diabetes, chronic obstructive pulmonary disease, or heart failure. ACO care quality measures were stratified by NP involvement and adjusted for patient, provider, and ACO factors. NP involvement was highest in larger ACOs, states that allow NPs full scope of practice, and rural areas. Greater involvement was associated with fewer readmissions and higher scores on measures of preventive care but not chronic disease and medication management. Greater NP involvement in ACOs was associated with improvement in some care quality measures. With NPs’ increasing involvement in ACOs, more research is needed to understand the NP role in processes and outcomes of care.
Mucinous Adenomyomatous Pulmonary Hamartoma: Clinicopathologic, Immunohistochemical, and Molecular Features of 6 Cases
Authors: Rossi Giulio , Cavazza Alberto , Comin Camilla , Jocollé Genny , Jukna Agita , Rotellini Matteo , Davoli Fabio , Colby Thomas
Published: July 2020

Pulmonary hamartoma (PH) may show various combinations of mesenchymal tissues with entrapment of respiratory epithelium. An uncommon variant of PH prevalently consisting of smooth muscle with mucinous proliferation has been reported in literature under several definitions as sporadic reports. We collected a series of 6 leiomyomatous PH associated with mucinous growth from consultation files (3 cases) and multicentric revision of archival files among 128 consecutive surgically resected PH. The lesions have a prevalence for male gender (5:1) and lower lobes (5:1), with a mean age at diagnosis of 61 years. All cases were incidentally disclosed in asymptomatic patients and had an indolent behavior. At histology, 2 cases consisted uniquely of smooth muscle and 4 also showed mature adipose tissue. The mucinous proliferation consisted of a monotonous growth of columnar cells lacking p63-positive basal cells and expressing pan-CKs, MUC5A, and CK7, but negative with TTF-1, napsin, MUC1, MUC2, MUC6, CK20, and CDX2. Smooth muscle was negative with hormonal receptors. Molecular analysis using a multiplex gene panel did not reveal gene mutations, while ALK, BRAF, and ROS1 were negative. In conclusion, we describe a small series of uncommon PH with prevalent leiomyomatous mesenchymal component associated with a mucinous growth (mucinous adenomyomatous hamartoma). Despite the lack of basal cells coating mucinous proliferation and irregular architecture, the favorable outcome and lack of molecular alterations most likely lay for a benign/low-grade tumor. Pathologists should be aware of this unusual occurrence to prevent a diagnosis of overt malignancy, particularly in frozen section, small biopsy, and cytology.
Twisted Liminalities
Authors: Carlson David Lee , McGuire Keon , Koro Mirka , Cannella Gaile
Published: July 2020

This introduction offers a brief and poetic introduction to historical uses of liminality. It also explains how authors in this special issue were tasked with thinking of liminalities as multiplicities or twisted liminalities. This means liminalities is not simply a rite-of-passage, but crosses time-spaces and can be a site of resistance within the contemporary moment. Also, liminalities can be an ontological position that challenges entrenched modes of conducting research. We encouraged authors to consider the concept of liminalities within the field of critical qualitative inquiry.
Representation of Intimate Partner Violence Against Women in Swedish News Media: A Discourse Analysis
Authors: Karlsson Nadja , Lila Marisol , Gracia Enrique , Wemrell Maria
Published: July 2020

Despite being rated as some of the world’s most gender equal countries, Sweden and neighboring Nordic nations show high rates of intimate partner violence against women (IPVAW). As the news media contribute to the shaping of public attitudes, this article pursues a two-step discourse analysis of how IPVAW was represented in seven Swedish newspapers during 2018. Although an individualistic discourse on IPVAW was found to be most prevalent, articles where perpetrators were presented as non-Swedish more frequently contained a structural framing of IPVAW. This confirms previously noted tendencies toward individualization and othering of IPVAW in Sweden.