GENERALIZED URTICARIA AS A VASCULITIC MANIFESTATION IN A PATIENT WITH SARS-CoV-2 INFECTION: A CASE REPORT IN COLOMBIA
Authors:   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia, Sepúlveda-Beltran Daniela , Mondragón-Cardona Alvaro ,   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia,   Universidad Surcolombiana, Neiva, Huila, Colombia, Conde-Martin Carlos Enrique ,   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia,   Infectious Diseases Department, Sociedad Clínica Emcosalud, Neiva, Huila Colombia, Lopez-Guevara Oscar Alberto ,   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia, Hernandez-Rojas Nubia Rocio ,   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia, Caviedes-Cleves Mario Alberto ,   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia, Gutierrez-Ortega David E. ,   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia, Rangel-Meza Carmen R. ,   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia, Conde-Tavera Franci Karina ,   Internal Medicine Department, Sociedad Clínica Emcosalud, Neiva, Huila, Colombia,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia, Rodriguez-Morales Alfonso J. ,   Latin American Network of Coronavirus Disease 2019 (COVID-19) Research (LANCOVID-19), Pereira, Risaralda, Colombia,   Grupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia, Dhama Kuldeep ,   Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly-243122, Uttar Pradesh, India
Published: April 2021

Skin manifestations have been reported in up to 20% of cases of SARS-CoV-2 infection, including morbilliform rash (22%), pernio-like acral lesions (18%), urticaria (16%), and macular erythema (13%). It is believed that in the case of SARS-CoV-2 infection, the mechanism involved is an inflammatory response that generates immune dysregulation, vascular congestion, vasculitis, vascular thrombosis, or neoangiogenesis. This case study, present the case of a patient with no previous history of urticarial reactions, autoimmune diseases, or exposure to medications who develops generalized urticaria lasting more than 24 hours and who was diagnosed with SARS-CoV-2 infection by RT-PCR with a nasopharyngeal swab. We suggest in this patient vasculitic urticaria as a manifestation of SARS-CoV-2 infection.