bluuebunny/crossref_metadata_2025 huggingface dataset:
Macrophage Polarization in Left Ventricular Structural Remodeling Induced by Hypertension
Authors: Wu Xiaolin , Wu Qiaolan , Gao Lin , Lv Yu , Wu Zhichun
Published: April 2024

Following long-term hypertension, mechanical stretching and neuroendocrine stimulation, cause multiple heterogeneous cells of the heart to interact, and result in myocardial remodeling with myocardial hypertrophy and fibrosis. The immune system, specifically macrophages, plays a vital role in this process. Macrophages are heterogeneous and plastic. Regulated by factors such as microenvironment and cytokines, polarization can be divided into two main forms: M1/M2, with different polarizations playing different roles in left ventricular structural remodeling associated with hypertension. However, descriptions of macrophage phenotypes in hypertension-induced myocardial hypertrophy models are not completely consistent. This article summarizes the phenotypes of macrophages in several models, aiming to assist researchers in studying macrophage phenotypes in hypertension-induced left ventricular structural remodeling models.
Electroencephalography Monitoring for Preventing Postoperative Delirium and Postoperative Cognitive Decline in Patients Undergoing Cardiothoracic Surgery: A Meta-Analysis
Authors: Xue Song , Xu Ao-xue , Liu Hong , Zhang Ye
Published: April 2024

Background: Patients undergoing cardiothoracic surgery frequently encounter perioperative neurocognitive disorders (PND), which can include postoperative delirium (POD) and postoperative cognitive decline (POCD). Currently, there is not enough evidence to support the use of electroencephalograms (EEGs) in preventing POD and POCD among cardiothoracic surgery patients. This meta-analysis examined the importance of EEG monitoring in POD and POCD. Methods: Cochrane Library, PubMed, and EMBASE databases were searched to obtain the relevant literature. This analysis identified trials based on the inclusion and exclusion criteria. The Cochrane tool was used to evaluate the methodological quality of the included studies. Review Manager software (version 5.3) was applied to analyze the data. Results: Four randomized controlled trials (RCTs) were included in this meta-analysis, with 1096 participants. Our results found no correlation between EEG monitoring and lower POD risk (relative risk (RR): 0.81; 95% CI: 0.55–1.18; p = 0.270). There was also no statistically significant difference between the EEG group and the control group in the red cell transfusions (RR: 0.86; 95% CI: 0.51–1.46; p = 0.590), intensive care unit (ICU) stay (mean deviation (MD): –0.46; 95% CI: –1.53–0.62; p = 0.410), hospital stay (MD: –0.27; 95% CI: –2.00–1.47; p = 0.760), and mortality (RR: 0.33; 95% CI: 0.03–3.59; p = 0.360). Only one trial reported an incidence of POCD, meaning we did not conduct data analysis on POCD risk. Conclusions: This meta-analysis did not find evidence supporting EEG monitoring as a potential method to reduce POD incidence in cardiothoracic surgery patients. In the future, more high-quality RCTs with larger sample sizes are needed to validate the relationship between EEG monitoring and POD/POCD further.
Correlation between Metabolic Parameters and Warfarin Dose in Patients with Heart Valve Replacement of Different Genotypes
Authors: Wang Xiaowu , Zhao Diancai , Ma Jipeng , Wang Xia , Liu Jincheng
Published: April 2024

Background: Warfarin has become the first choice for anticoagulation in patients who need lifelong anticoagulation due to its clinical efficacy and low price. However, the anticoagulant effect of warfarin is affected by many drugs, foods, etc. accompanied by a high risk of bleeding and embolism. The Vitamin K epoxide reductase complex 1 (VKORC1) and Cytochrome P450 2C9 (CYP2C9) genotypic variation can influence the therapeutic dose of warfarin. However, it is not clear whether there is a correlation between warfarin dose and liver function, kidney function and metabolic markers such as uric acid (UA) in patients with different genotypes. We performed a single-center retrospective cohort study to evaluate the factors affecting warfarin dose and to establish a dose conversion model for warfarin patients undergoing heart valve replacement. Methods: We studied 343 patients with a mechanical heart valve replacement, compared the doses of warfarin in patients with different warfarin-related genotypes (CYP2C9 and VKORC1), and analyzed the correlation between liver function, kidney function, UA and other metabolic markers and warfarin dose in patients with different genotypes following heart valve replacement. Results: Genotype analysis showed that 72.01% of patients had CYP2C9*1/*1 and VKORC1 mutant AA genotypes. Univariate regression analysis revealed that the warfarin maintenance dose was significantly correlated with gender, age, body surface area (BSA), UA and genotype. There was no correlation with liver or kidney function. Multiple linear regression analysis showed that BSA, genotype and UA were the independent factors influencing warfarin dose. Conclusions: There is a significant correlation between UA content and warfarin dose in patients with heart valve replacement genotypes CYP2C9*1/*1/VKORC1(GA+GG), CYP2C9*1/*1/VKORC1AA and CYP2C9*1/*1/VKORC1AA.
Paving Evolutionary Path with Experience Transition in Dynamic Capabilities
Authors: Cheng Yu-Ching
Published: April 2024

The dynamic capabilities approach underscores the role of experience
accumulation as a firm- specific resource in sustaining a competitive
advantage through evolutionary paths. However, little is known about
experience transition and its effect on firm performance. This topic is
important because it touches upon a long-standing debate about strategy
commitment and flexibility. To explain and predict experience
transition, this study draws insights from sequence analysis to examine
the effects of sequence stability. Drawing from the acquisition
sequences of 234 publicly traded firms within the biotechnology industry
from 2012 to 2019, this study corroborates with the dynamic capabilities
approach and finds that the significantly negative effect of sequence
stability is contingent upon complementary assets. While a negative
relationship exists between sequence stability and advertising
investment, the causal direction reverses when the interaction term
shifts to physical capital investment. This study contributes to the
resource-based view by highlighting that successful experience
transition depends on resource alignment with corporate strategy.
ScholarOne - A STUDY ON HIGH SCHOOL TEACHERS' RECOGNITION OF MATHEMATICS QUESTIONS IN THE CHINESE COLLEGE ENTRANCE EXAMINATION UNDER THE CONNECTION OF TEACHING AND EXAMINATION
Authors: Su Hongyu , Jiang Xueping , Yang Yang
Published: April 2024

High school teachers’ understanding and recognition of the examination
questions affect the quality of teaching. Three dimensions constitute
the test acceptance: high school teachers’ recognition of the difficulty
of the Chinese Mathematics College Entrance Examination, recognition of
innovative question types and satisfaction of students’ answer
questions. Through questionnaires and interview surveys, teachers’
recognition of the examination questions was analyzed comprehensively.
There are significant differences in the recognition of test difficulty
and innovative question types among teachers from different regions and
different ages. Based on the connection between teaching and
examination, this paper puts forward some discussions on mathematics
teaching in senior high school and Chinese Mathematics College Entrance
Examination questions.
ScholarOne - IMPACT OF INTERNATIONAL MONETARY FUND PROGRAMMES ON GHANAIAN ECONOMY: EMPHASIS ON 1992-2024 PERIOD
Authors: Dumevi Andrews , Mfiya Fanny , Zhang Zhuo
Published: April 2024

The assessed how IMF Extended Credit Facility programme was managed
prior to the singing the programmes in 2015 and in 2023, using Nudge
theory and how this change management affect the macro-economic and
social conditions in Ghana. The use used questionnaire to collect data
from 127 experts from think-tank institutions and public universities in
Ghana. Also, some of these experts were interviewed. The questionnaire
data was analyzed using percentages, independence samples t-test and
Point-Biserial Correlation. The interview data was analyzed using
content analysis. 2015 IMF Extended Credit Facility programme was better
managed than 2023 IMF Extended Credit Facility programme. Also, 2015
programmes brought more positive macroeconomic and social gains to
Ghana. However, less macroeconomic and social gains are expected from
2023 programme. How the IMF Extended Credit Facility programme is
managed prior to signing the programme have statistically significant
effect on the macroeconomic and social gains from the programme.
Government should effectively adhered to and apply change management
theories like Nudge theory when they want to sign to IMF Extended Credit
Facility programme to ensure positive outcomes of the gains. This
article aims to Make a Difference (MAD) by positioning the change
management in the context of IMF Extended Credit Facility programmes.
This study is thus first in its king to assess change management of IMF
programmes, using Nudge theory and relevance of such change management
to the programme’s outcomes. The study may help inform governments how
to manage any external programme especially in the period prior to
signing
Structural-semantic and ethnocultural features of karachay-balkarian paremic statements with the zoo component it “dog”
Authors:   Kabardino-Balkarian State University named after H.M. Berbekov, Mussa B. Ketenchiev , Alim K. Appoev ,   Institute for the Humanities Research – Affiliated Kabardian-Balkarian Scientific Cen-ter of the Russian Academy of Sciences, Akhmat M. Miziev ,   Kabardino-Balkarian State University named after H.M. Berbekov
Published: April 2024

The article examines Karachay-Balkarian paremic utterances with a zoonymic component “dog”, as well as their structural, semantic, and ethnocultural characteristics. According to the paper, such syntactic constructions are diverse because dogs are important in traditional society. For the same reason, they are variable, with structural variation determined by the interchangeability of the sentence’s constituents, represented by names, verbs, and phrases. This has a significant im-pact on their paradigmatics, as affirmative and negative constructions are more commonly repre-sented. The Karachay-Balkarian paremic fund is dominated by proverbial structures modeled after simple sentences. Proverbs that resemble complex sentences, as well as polynomial paremic statements, have found their niche. All of them are ethno- and linguoculturally marked, represent-ing a relevant segment of the global national picture.
About some samples of clothes in the Oguz epic “Kitabi-Dede Gorgud” and their parallels in the traditional clothes of Azerbaijanis
Authors: Abdulova Gulzade
Published: April 2024

The article deals with samples of Turkic clothing in the epos “Kitabi-Dede Gorgud”. Attention is drawn to some unexplored moments of some elements of clothing, such as their shape, history of occurrence, etymology, ethnographic parallels are drawn. The names of oronyms and toponyms associated with the names of clothes in the areas where the events described in the epos “Kitabi-Dedе Gorgud” supposedly took place are given.
Medieval handmade ceramics of Uigarak settlement in Central Asia
Authors: Barinova Elena
Published: April 2024

The archaeological material that formed the basis of this article was brought from the Eastern Aral Sea region during the many years of work of the Khorezm expedition of the USSR Academy of Sciences and was kept in expeditionary storage facilities for a long time. The aim of the work was to carry out a detailed classification and typologization of handmade ceramics of the Uygarak settlement and to identify the chronology and sequence of settlement of this territory during the Middle Ages.
The historical development of the titles of rulers of the Saudi State
Authors: Al-Otaibi Mariam Khalaf Shadid
Published: April 2024

This historical political study aimed to track the historical and political development of the Saudi family's titles, imposed by the nature of the transition of the Saudi State from a simple state to a modern state in its legal sense, since its unification in 1351 A.H. /1932 A.D. to the present time 1443 A.H. / 2022 A.D. The Saudi State has gone through many changes in its political titles. According to the author, it is important for understand the Saudi State's political changes. The study used a historical approach, analyzing British papers from King Abdul-Aziz Al Saud's reign.
Keep Off the Moors: The Road to Data Archival Storage
Authors: Cachola Ellen-Rae , Huffman Brian
Published: April 2024

The William S. Richardson School of Law Library has embarked on a journey to develop their archival collections. This article outlines the steps to assess the archival and record-keeping context of an institution in order to plan the installation and development of repositories and technology to support the access and curation to digital collections and electronic records.
Investigating Librarian Perspectives on Generative AI
Authors: Johansen Jesper Solheim , Headley Christian , Figenschou Lars
Published: April 2024

This study investigates librarians' perspectives on generative artificial intelligence (AI) in libraries. Librarians (n = 52) from 21 different institutions attended a workshop to discuss generative AI and assess the ethics of various applications of large language models (LLMs) in research. Through the analysis of qualitative workshop data, we identified 24 overarching themes — 15 concerns related to embracing AI, 4 about not embracing it, and 5 possible interventions for libraries. Additionally, assessments revealed a nuanced view of the ethical considerations associated with LLMs in research. High ethical ratings were given to use cases involving language feedback and learning support. Lower ratings were associated with generative AI imitating professional roles and generating text based on user input. Furthermore, we found mixed opinions on several use cases among the participants, demonstrating the difficulty of establishing clear guidelines. This paper presents the preliminary findings from a research and development project, offering insights into the perspectives of librarians on generative AI. It underscores the need for a balanced, informed approach to integrating generative AI in libraries.
What Taft-Hartley Did to Joint-Employer Doctrine
Authors: Pandya Sachin S.
Published: April 2024

In the debate over joint-employer doctrine under the National Labor Relations Act (NLRA), the prevailing view is that, because of how the Taft-Hartley Act of 1947 amended the NLRA, the NLRA’s joint-employer legal standard must be consistent with the common-law of agency. This paper argues that this view is unsound. Taft-Hartley does not require the NLRA’s joint-employer legal standard to be consistent with the common-law of agency, and thus does not constrain how the National Labor Relations Board develops its joint-employer doctrine. To support this argument, the paper examines not only statutory text and legislative history, but also, among other sources, an original hand-coded dataset of National Labor Relations Board opinions issued in the decade before Taft-Hartley. The paper then shows what its argument implies not only for the NLRA, but also statutes with similarly drafted provisions, such as Title VII of the Civil Rights Act of 1964.
Deconstructing the Gender-Equality Paradox
Authors: Ilmarinen Ville Juhani , Lönnqvist Jan-Erik
Published: April 2024

Studies advancing the hypothesis of a “gender-equality paradox” have found that societies with more gender equality demonstrate larger gender differences across a range of phenomena. In doing so, they rely on that practice of predicting an algebraic difference score—calculated from mean scores for men and women across a set of countries—with an index of gender equality, or some related concept. We argue that direct difference score predictions of this type are impossible to interpret because very different combinations of constituents—mean scores of men and women and properties of these means—can produce identical direct difference score predictions. We reanalyzed three large cross-cultural datasets with fifteen variables from three different domains—attitudes towards science and technology, economic preferences, and personality traits—to showcase our method of deconstructing difference score predictions and to investigate to what extent the rhetoric of the gender-equality paradox describes a real phenomenon. The results were highly heterogeneous. For some characteristics, men’s and women’s country-level means varied identically as a function of country-level gender equality (no paradox). For other characteristics, there were differences in how men’s and women’s means varied. Whether these differences could be described in the rhetoric of the paradox varied. More pertinent is the necessity of deconstructing difference score predictions into their constituent components before attempting to answer questions regarding a paradox. It is in the terminology of these components and their properties that future hypotheses should be tested.
The role of implicit content for lie and truth judgments: A cross-cultural study
Authors: Wiegmann Alex , Reins Louisa Marie , Mizumoto Masaharu , Erut Alejandro , Li Qilin , Orr Shirly
Published: April 2024

Misinformation plays an important role in our lives, be it lies told in everyday conversations or false information spread on social media websites. But when do people consider a statement to be false or an instance of lying, and do these judgements differ between cultures? In the present paper, we shed new light on these questions by examining to what extent implicit content affects judgements of lying and falsity. 3,660 participants from ten countries (Chile, China, Germany, Israel, Japan, Mexico, South Africa, Spain, the UK, the US) were presented with deceptive implicatures—i.e. utterances that are literally true but implicitly convey false information—and were then asked whether each speaker lied and whether something true or false was said. Our results show that implicit content plays an important role in people’s judgements, leading certain utterances to be judged as false or lies even when they are explicitly true. Also, the result patterns were strikingly similar across countries.
Enhancing Caregiver Sensitivity: Efficacy of a Single-Session, Video-Based Training for New Parents
Authors: Piersiak Hannah , Takemoto Sydney , Bailes Lauren G. , Kwasneski Kate , Salo Virginia C. , King Lucy S , Humphreys Kathryn Leigh
Published: April 2024

Caregiving interventions are typically personalized and time intensive, creating barriers to access and use. To address these limitations, in a pre-registered study of 120 first-time parents (93 mothers, 27 fathers) of 4- to 6-month-old infants, we tested the impact of a standardized, interactive, single-session video-based intervention (Teach by Example [TbE], which instructed participants (N=60) to view caregiver–child interactions and rate caregiver sensitivity, warmth, and intrusiveness, as compared to a written information condition, which instructed participants (N=60) to read about these three caregiving behaviors. Post-intervention, participants assigned to TbE, compared to those in the written information condition, were coded as more sensitive and less intrusive in their caregiving during an interaction with their infant, reported lower levels of impaired affiliation with their infant, and greater parental self-efficacy. Group differences in warmth were moderate and not statistically significant. Findings support the promise of TbE, a single-session online intervention, for first-time parents.
A universal of human social cognition: Children from 17 communities process gaze in similar ways
Authors: Bohn Manuel , Prein Julia Christin , Ayikoru Agnes , Bednarski Florian Markus , Dzabatou Ardain , Frank Michael C. , Henderson Annette M E , Isabella Joan , Kalbitz Josefine , Kanngiesser Patricia , Keşşafoğlu Dilara , Koymen Bahar , Manrique-Hernandez Maira , Magazi Shirley , Mújica-Manrique Lizbeth , Ohlendorf Julia , Olaoba Damilola , Pieters Wesley , Pope-Caldwell Sarah , Slocombe Katie , Sparks Robert Zane , Sunderarajan Jahnavi , da Silva Vieira Wilson Filipe , Zhang Zhen , Zong Yufei , Stengelin Roman , Haun Daniel
Published: April 2024

Theoretical accounts assume that key features of human social cognition are universal. Here we focus on gaze-following, the bedrock of social interactions and coordinated activities, to test this claim. In this comprehensive cross-cultural study spanning five continents and 17 distinct cultural communities, we examined the development of gaze-following in early childhood. We identified key processing signatures through a computational model that assumes that participants follow an individual’s gaze by estimating a vector emanating from the eye-center through the pupil. Using a single reliable touchscreen-based task, we found these signatures in all communities, suggesting that children worldwide processed gaze in highly similar ways. Absolute differences in performance between groups are accounted for by a cross-culturally consistent relationship between children’s exposure to touchscreens and their performance in the task. These results provide strong evidence for a universal process underlying a foundational socio-cognitive ability in humans that can be reliably inferred even in the presence of cultural variation in overt behavior.
AI-Driven Customization in Financial Services: Implications for Social Innovation in Nepal
Authors: Khadka Srijana , Rai Bharat , Khadka Ajaya Kumar
Published: April 2024

The study examines the association and influence of Artificial intelligence (AI) adoption and social innovation on decision-making within the Nepalese banking sector. A descriptive and causal-comparative research design is employed in the study. With a purposive sampling design, the study used 230 respondents from commercial banks in Nepal. The study findings show that AI technologies (β = 0.205) and social innovation (β = 0.395) significantly contribute to decision-making (|p < 0.05|). The study scrutinizes specific approaches for fostering social innovation by implementing AI-driven decision-making. Findings revealed meaningful associations between AI, social innovation, and decision-making, emphasizing the interconnected nature of these elements. The study identifies actionable strategies for leveraging AI to promote social innovation. The research implications extend to strategic management, urging financial institutions to integrate AI technologies strategically, aligning technological advancements with societal needs, and fostering a holistic approach to responsible AI adoption. This study contributes valuable insights to the evolving discourse on AI in financial services, providing a nuanced understanding of its implications for decision-making and social innovation within the unique context of Nepalese commercial banks.
POTENSI SERAPAN KARBON EKOSISTEM MANGROVE DI DESA EYAT MAYANG KABUPATEN LOMBOK BARAT
Authors: Sari Diah Permata , Idris Muhamad Husni , Aji Irwan Mahakam Lesmono , Anwar Hairil , Webliana B. Kornelia
Published: April 2024

Pendataan kondisi biofisik ekosistem mangrove merupakan langkah awal dalam pengelolaan kawasan mangrove yang meliputi data struktur dan komposisi ekosistem mangrove serta potensi serapan karbon.  Data potensi serapan karbon di kawasan ekosistem mangrove Desa Eyat Mayang belum terindentifikasi. Tujuan dari penelitian ini yaitu untuk menganalisis potensi serapan karbon di kawasan ekosistem mangrove Desa Eyat Mayang.  Pengumpulan data  menggunakan metode jalur berpetak sebanyak 84 plot. Data dianalisis menggunakan persamaan allometrik.  Hasil penelitian menujukkan bahwa kawasan ekosistem mangrove di Desa Eyat Mayang memiliki potensi biomassa 86,27 ton/ha yang terdiri dari 84% biomassa atas (AGB) dan 16% biomassa bawah permukaan (BGB).  Potensi kandungan karbon mangrove di Desa Eyat Mayang sebesar 40,13 ton/ha dan potensi serapan karbon (CO2) sebesar 147,3 ton/ha.  Kontribusi terbesar biomassa, kandungan karbon dan serapan karbon berasal dari jenis Rhizophora apiculata.
PENGARUH NAUNGAN TERHADAP PERTUMBUHAN DAN HASIL TIGA VARIETAS CABAI MERAH (Capsicum annuum L.).
Authors: Ramayana Abdul Syamad , Supriyanto Bambang , Pranoto Hadi , Susylowati Susylowati , Nurahman Arip
Published: April 2024

Tujuan penelitian adalah untuk mengetahui interaksi naungan terhadap pertumbuhan dan hasil tiga varietas cabai merah, mengetahui naungan yang dapat memberikan pertumbuhan dan hasil varietas cabe merah terbaik, dan mengetahui varietas cabe merah yang memberikan pertumbuhan dan hasil terbaik.Penelitian telah dilaksanakan dari bulan Juni sampai Oktober 2019 di Jl Sambaliung, Universitas Mulawarman Samarinda Kalimantan Timur.Penelitian ini disusun dalam Rancangan Petak Terbagi/Split Plot Design 3x5 yang diulang sebanyak 5 kali.  Sebagai petak utama adalah perlakuan naungan (N) yang terdiri dari 3 taraf yaitu, 0%, 25 %, dan 50 %, serta sebagai anak petak adalah perlakuan varietas (V) yang terdiri dari 3 taraf yaitu, Darmais F1, Astina F1 dan Tanaka F1. Data yang diperoleh dianalisis dengan menggunakan sidik ragam. Apabila terdapat pengaruh nyata maka untuk membandingkan antara rata-rata dua pelakuan dilanjutkan dengan uji BNT 5 %.Hasil analisis sidik ragam menunjukkan bahwa tidak terdapat interaksi antara perlakuan naungan dan varietas cabai merah, perlakuan naungan berpengaruh tidak nyata terhadap semua variabel pengamatan, begitu juga dengan perlakuan varietas berpengaruh tidak nyata terhadap semua variabel pengamatan.
Doktrin Res Ipsa Loquitur Pada Perlindungan Konsumen
Authors: Angela Irene Maria , Suryamah Aam , Yuanitasari Deviana
Published: April 2024

Economic growth in Indonesia can be encouraged by increasing consumer confidence. In the event of a violation of consumer rights, consumers have the right to claim compensation from business actors, but in fact, consumers and business actors have an unequal position. Consumers have difficulties in terms of civil evidence. An imbalance in the distribution of the burden of proof is an injustice for the disputing parties. The research was conducted using normative juridical research methods and comparative research methods, namely research methods carried out by studying secondary data and library materials and approaches to comparing the laws of one country with the laws of other countries. This research was conducted through library research and field research to enrich the sources. The results of further research are described in descriptive writing that relates the problem to legal theory in evaluating the practices carried out by research objects. There are 2 conclusions from the research results. First, that the position of the re ipsa loquitur doctrine in the principle of proof in consumer protection cases is closely related to the evidence imposed by judges on business actors as parties who have responsibility for the products consumed by consumers as well as those who suffer less losses to provide more justice for consumers. and in line with the principle of proof contained in UUPK and the second conclusion is that the res ipsa loquitur doctrine can be applied in cases of consumer protection if it fulfills the elements that are the requirements of the application of the re ipsa loquitur doctrine.
Naskah Akademik: Inkonsistensi Peraturan Dan Keterlibatan Pendidikan Tinggi
Authors: Alfaris Muhammad Ramadhana
Published: April 2024

The purpose of this research is to determine the form of unclear norms in the preparation of academic texts, and to determine the involvement of universities through academic texts in the formation of regional regulations. The method used in this research uses normative legal research methods which raise the theme of legal systematics or the systematics of statutory regulations with vertical and horizontal levels of synchronization, with legal, conceptual, historical, theoretical and interpretive approaches. The results of this research show that explanatory words or adverbs, and/or academic texts have very different positions so that their diction cannot be in harmony because each position is very different. Apart from that, there are inconsistencies in norms which cause laws and regulations to be out of sync with each other, so that there is no normative harmonization from a vertical and/or horizontal perspective. Meanwhile, higher education institutions' involvement in academic texts is still situationally involuntary, namely a temporary situation within the limits of academic paper preparation activities and there is no aspect of continuity of this involvement. Thus, the position of academic texts is very respectable, however, in terms of legal norms governing academic texts, they are still not clear, so there is no legal certainty.
A Landscape Study to Determine the Innovation Mortality Rate in Health Technology Innovations Across the Globe
Authors: Ramesh Sambhu , Nithyavathani J Annie , Syed Moinudeen , Kachroo Kavita , Sharma Jitendra Kumar , Priyadarshini A. , Latha Penta Sneha , Chowdary Sushmita Roy
Published: April 2024

Introduction : Health technology innovation encompasses many areas, such as medical devices, diagnostics, pharmaceuticals, digital health solutions, telemedicine, health informatics, and more. These innovations aim to enhance healthcare delivery, improve patient outcomes, increase access to services, reduce costs, and advance medical research.
Methodology : We have analyzed health technology innovations reported between January 2011 and December 2022. Regulatory approval for the innovative products was determined based solely on official open-access websites of health agencies, disregarding information from company websites or third-party sources. The search process utilized identified innovation agencies and sources like Primary Health Care (Innovations were thoroughly examined from these sources, focusing on health technologies, and success was gauged through regulatory approval.
Results : The WHO Compendium includes 200 health innovations primarily intended for low-resource settings, with the USA accounting for the highest number, followed by India, the only low- and middle-income country (LMIC) with significant innovations. However, 58% of the listed innovations did not obtain regulatory clearance. Medical devices dominated the listed innovations, while scalable assistive technologies were limited. Global innovation agencies, particularly Grand Challenges, supported many innovations, but the regulatory approval rate remained low. In India, BIRAC supported 92% of the mapped innovations, with a similar trend of low regulatory approval rates.
Conclusion: The study observed the highest number of innovations during 2015-2017, with medical devices being the most prominent category. However, most innovations from both global and domestic agencies were unapproved, raising concerns about regulatory clearance for these health technologies.
Manuscript Highlights: The manuscript presents several important highlights concerning health technology innovation and regulatory approval. It highlights the evaluation of health innovations from 2015 to 2022, focusing on their success rate based on health agency approval. It reveals an uneven distribution of innovations from different countries and emphasizes the need for critical interventions to improve the process. This study emphasizes the significance of innovations in achieving healthcare equity and sustainable development goals.
Strengthening Evaluation Capacity Building Practice Through Competition: The Max Bell School of Public Policy’s Evaluation Capacity Case Challenge
Authors: Fierro Leslie A. , Bourgeois Isabelle , Gokiert Rebecca , Searle Michelle , Tremblay Melissa
Published: April 2024

Despite the attention evaluation capacity building (ECB) has received over the past several decades, surprisingly few opportunities for learning about ECB exist. In response to this need, the Max Bell School of Public Policy at McGill University, in collaboration with ECB scholars across Canada, created a case competition focused exclusively on ECB—the Evaluation Capacity Case Challenge (EC3). Twenty individuals interested in learning about ECB and one organization (case site) interested in enhancing their existing evaluation capacity were selected to participate through a competitive application process. Participants attended a series of online workshops and engaged with an ECB coach to hone their skills and then took part in a two-day hybrid case challenge event where they had 24 hours to craft an ECB plan in response to a specific case challenge question presented by case site representatives. In this article, the authors describe EC3 in detail and share some key reflections from the inaugural year.
AMEDI Jalisco, una lucha constante por los derechos democráticos y la participación ciudadana
Authors: Mejía Picón Diego
Published: April 2024

Evidentes ejemplos de la inequidad en los medios mexicanos se han atestiguado en 2008. Año que presenta una confluencia de coyunturas mediáticas que concierne a legisladores, empresas mediáticas y a la sociedad en general.
Presentación Por el arte de documentar y recordar
Authors: Larrosa–Fuentes Juan S.
Published: April 2024

Dice Niklas Luhmann: “Lo que sabemos sobre la sociedad y aun lo que sabemos sobre el mundo, lo advertimos a través de los medios de comunicación de masas”. La aseveración del sociólogo alemán es contundente y podría ser muy discutida. Sin embargo, difícilmente podremos destruir su argumento, en el que nos dice, palabras más palabras menos, que los medios de comunicación se han convertido en una de las principales fuentes de información en las sociedades modernas. Con esta y otras ideas en la cabeza, desde hace ya algunos años, profesores de la Carrera de Ciencias de la Comunicación nos dimos a la tarea de construir el proyecto de un dispositivo universitario que tuviera la capacidad de hacer observaciones críticas a los medios de comunicación del entorno, sobre todo, entendiendo la trascendencia que éstos tienen para la sociedad, pero en lo particular para el ejercicio de un comunicador.
El nuevo uso del dinero público
Authors: Ronalds Casillas Alejandro
Published: April 2024

Es de vital importancia poner en perspectiva lo que ha sucedido con el dinero público desde que Emilio González Márquez llegó al gobierno del estado de Jalisco. El tema no es menor y ha sido consignado por los principales medios de comunicación del país, se ha debatido en muchas columnas políticas y lo más importante, ha generado profundas insatisfacciones y divisiones entre la sociedad.
¿Y en qué estación quedó mi locutor?
Authors: López Álvarez Fabiola E.
Published: April 2024

2008 ha sido un año de grandes escándalos en el mundo periodístico y de los medios de comunicación. Las inesperadas salidas de periodistas de sus espacios informativos en televisión y radio, han dado mucho de qué hablar, pues en la mayoría de los casos se desconoce el porqué de sus ausencias. En este texto documentamos, de forma general, las sorpresivas partidas de algunos conductores radiofónicos de la Frecuencia Modulada (FM) en Guadalajara.
Actualización sobre las pruebas diagnósticas de la infección por el virus de la inmunodeficiencia humana en gestantes
Authors: Álvarez-Carrasco Ricardo
Published: April 2024

El diagnóstico precoz y la adecuada interpretación de las pruebas para diagnosticarinfección por el virus de la inmunodeficiencia humana (VIH) son muy importantesdurante la gestación. Para ello es fundamental conocer las características de talesensayos de manera de tomar decisiones oportunas y correctas. El presente artículotiene como propósito divulgar el entendimiento y la correlación de los resultadosde las pruebas usadas actualmente y su organización en el algoritmo diagnósticonacional.
Importancia de la cirugía fetal en la solución de problemas fetales durante la gestación
Authors: Gil Guevara Enrique
Published: April 2024

La medicina avanza a pasos agigantados y esto gracias al desarrollo dela tecnología en el diagnóstico y tratamiento de diversas enfermedades.
Sin lugar a duda en el ramo de la obstetricia, después de la perinatolo-gía, ha surgido hace unas décadas la medicina fetal.
Cribado de cardiopatías congénitas previo a la cirugía fetal
Authors: Gil Guevara Enrique , Valdez Guerra Isabel , Muñoz Acosta Jairo
Published: April 2024

Las cardiopatías congénitas son las malformaciones más frecuentes y significan unaalta tasa morbimortalidad neonatal, sobre todo en aquellos neonatos sin diagnósticoprenatal oportuno. Representan la primera causa de muerte infantil asociada amalformaciones congénitas. El avance de la tecnología y la estandarización de losprotocolos de diagnóstico ecográfico han permitido identificar cada vez con másprecisión las cardiopatías congénitas. Sin embargo, esto no ha sido suficiente y siguehabiendo una alta tasa de neonatos con cardiopatías congénitas no diagnosticadasen la vigilancia prenatal. Por otro lado, con el advenimiento de la cirugía fetal sehace necesario identificar la presencia de alguna cardiopatía congénita mayorque pudiera ensombrecer el pronóstico asociado con la patología fetal de fondoque hizo necesaria la intervención intrauterina. Considerando lo anterior, senecesita concientizar tanto a los padres como a los profesionales médicos sobrela importancia del cribado de cardiopatías congénitas, especialmente en aquellosfetos que van a ser sometidos a cirugía prenatal. Actualmente existe una alta tasade errores en el tamizaje de cardiopatías congénitas, lo que ocasiona ansiedad enlos padres. Esto puede deberse a una técnica inadecuada en la toma de imágenes,falta de estandarización en el protocolo de estudio basado en las guías practicasclínicas, o bien la falta de entrenamiento adecuado para realizar este tipo deestudios. El presente artículo se enfoca en los errores más comunes en el tamizajede cardiopatías congénitas durante la ecografía morfológica del segundo trimestre,tomando como base las guías practicas clínicas de ecocardiografía fetal.
Diagnóstico prenatal de esclerosis tuberosa en asociación con rabdomiomas: comunicación de caso y discusión de la importancia del diagnóstico molecular
Authors: Vallenas Campos Rosa E. , Eustaquio Briceño Luis A. , Huertas Tacchino Erasmo , Ibáñez Rodriguez Cecilia , Sosa Paucar Héctor , Castillo Urquiaga Walter , Torres Sotomayor Katty C.
Published: April 2024

El complejo esclerosis tuberosa (CET) se caracteriza por desarrollar hamartomasen diversos tejidos. Se presenta el caso de una paciente de 39 años con feto conmúltiples rabdomiomas en quien se realizó diagnóstico prenatal molecular de CET.Con el diagnóstico confirmado se amplió la evaluación en el posnatal, encontrándosemáculas hipopigmentadas en piel y múltiples túberes corticales y subependimarios.En la evaluación familiar, el padre presentó lesiones cutáneas y está en estudiopara confirmar CET. A los 6 meses de vida, la lactante permanece asintomática. Eldiagnóstico de CET prenatal tiene un impacto en el pronóstico del paciente y sufamilia. Mejora el pronóstico neurológico posnatal, permite extender la búsquedade la enfermedad a padres y hermanos, aporta herramientas para consejería másprecisa del embarazo y planificación familiar.
Cuidemos del Garbancillo de Tallante: guía didáctica sobre la conservación Astragalus nitidiflorus en su hábitat potencial en la Región de Murcia
Authors: Vicente Colomer María José , Martínez Sánchez Juan José , Naveira Ruíz Desirée , Segura Carreras Francisco José , Conesa Gallego Encarnación , Franco Leemhuis José Antonio , Bañón Arias Sebastián del Pilar , Aguado López Mayra , Martínez Díaz Eulalia , Ochoa Rego Jesús , Esteva Pascual Juan , Fernández Hernández Juan Antonio , Martínez López Juan Antonio , Álvarez Rogel José , Conesa Alcaraz Hector Miguel
Published: April 2024

Astragalus nitidiflorus, el Garbancillo de Tallante, es una planta que vive exclusivamente al oeste del Campo de Cartagena y que tiene una historia fascinante para la Botánica. Después de haber estado desaparecida durante casi 100 años, en 2004 fue redescubierta para formar parte de la identidad de las poblaciones de Tallante y Los Puertos de Santa Bárbara. Esta guía forma parte del material educativo dirigido a alumnos de educación primaria en el marco de la acción E1 del Proyecto LIFE11 BIO/ES/727 “Conservación de Astragalus nitidiflorus en su hábitat potencial en la Región de Murcia".
Conoce el Oeste
Authors: Aranda Mercader José Damián
Published: April 2024

El libro, a través de las 29 láminas dibujadas a mano por el propio autor y de las casi 150 fotografías que ilustran las 156 páginas de la obra, muestra la historia de esta zona del Campo de Cartagena y describe pozos, norias, aljibes, pedrizas, grandes construcciones hidráulicas, molinos, fortificaciones, ermitas y grandes árboles monumentales de la zona oeste de Cartagena.
Advanced frequency of thick FGM cylindrical shells with fully homogeneous equation
Authors: Hong CC
Published: April 2024

The effects of shear deformation theory and improved shear correction factors on the advanced computation of frequencies by using the fully homogeneous equation for thick functionally graded material (FGM) circular cylindrical shells are studied. It is quite reasonable to consider the extra advanced effect of third-order shear deformation theory (TSDT) of displacements on the varied shear correction coefficient. The values of advanced nonlinear shear correction coefficient are usually functions of the nonlinear coefficient term in TSDT, power-law exponent parameter, and environment temperature. The main achievements in the nonlinear case of displacements and with the varied value of shear correction coefficients, the non-dimensional fundamental frequencies are estimated, investigated, and compared with the values in the linear case. This paper aims to study the fundamental frequencies of very thick FGM cylindrical shells under the advanced effects of shear deformation theory and improved shear correction factors.
Evaluation of nutritional attitudes and behaviors of children aged six- to eight
Authors: Elmas Cemre , Gezer Ceren , Yurt Merve , Türkay Ezgi
Published: April 2024

The aim of thisThis study isaims to evaluate the nutritional attitudes and behaviorsbehaviours of 6-8 years -year-old children. A total of 347 students, 183 boys and 164 girls, aged 6-8, participated in the study. Data were collected by applying a survey form, including the Nutrition Attitude Scale and the Nutrition Behavior Scale, which questioned the demographic characteristics of the children, by the researcher. The children's Nutrition Attitude Scale mean score was 13.83±2.03, and their Nutrition Behavior Scale score was 2.57±4.53. A weak correlation was found between the children's nutritional attitude scores and their eating behaviorbehaviour scores (r=0.212, p<0.001). As a result of the study, it was seen that the healthy eating habits of the children participating in the study were at a moderate level. The results of this study show the need for interventions for children to have and maintain positive nutritional attitudes and behaviorsbehaviours.
Relationship of nutrition and physical activity with gut microbiota
Authors: Koca Melis , Koca Esabil Emrah , Ünal Turhan Emel
Published: April 2024

Diet and physical activities are factors that affect the diversity and composition of the intestinal microbiota. Human health is closely related to the balanced relationship between gut microbiota, physical activity and nutrition. It has been reported that the composition of the intestinal microbiota also varies in individuals fed with different diets such as high-carbohydrate diets, high-protein diets, high-fat diets, vegetarian/vegan diet, gluten-free diet and mediterranean diet. Depending on the type of food consumed, dietary components such as carbohydrates, proteins, fats, phytochemicals and vitamins have the potential to affect the intestinal microbiota balance positively or negatively. It is reported that a balanced gut microbiota supports the digestion and absorption of nutrients as well as exercise performance and thus contributes to metabolic activities. However, just as with the diet, the composition of the intestinal microbiota can change depending on the intensity and type of exercise. It has been reported that moderate physical activity causes positive changes in the intestinal microbiota, while long and strenuous activities have negative effects on the intestinal microbiota.
Quality characteristics of fish sausages made from African catfish (Clarias gariepinus)
Authors: Menchynska Alina , Manoli Tatiana , Ivaniuta Anastasiia , Ochkolias Olena , Stepanova Viktoriia
Published: April 2024

In the context of the problem of insufficient consumption of fish products, the possibility of creating high-quality sausage products based on new types of raw materials is considered. The development of high-quality fish sausages from new raw materials will expand the range of sausage products and provide the population with seafood products. The purpose of the study is to establish the feasibility of using African sharptooth catfish in the technology of fish sausage products. The study used a complex of generally accepted organoleptic, chemical, physicochemical methods of research: moisture content – by drying the sample to a constant weight; fat content – by the Soxhlet method; protein content – by the Kjeldahl method; ash – by burning the sample. The penetration stress was determined using a penetrometer; water activity index – using a hygrometer; the hydrogen index – using a pH meter. As a result of research, the feasibility of using the African sharptooth catfish as a raw material for making fish sausages is theoretically substantiated and experimentally confirmed (Clarias gariepinus Burchell, 1822). The effectiveness of combining catfish meat with other hydrobionts and animal raw materials is shown. New recipes for raw smoked sausages based on African catfish with the addition of mackerel, scallop, and lard have been developed. Organoleptic and physico-chemical indicators of quality and nutritional value of finished products were studied. The results of organoleptic evaluation showed the similarity of catfish sausages to conventional meat sausages. Fish flavour and aroma were poorly expressed in sample 2, which included only African catfish meat from fish raw materials, which determined its consumer preferences. Sample 3 obtained by combining African catfish meat with mackerel and scallop received high organoleptic scores. The results of a study of the chemical composition show a high nutritional value of sausage products based on the improved recipe. The moisture content in all samples did not exceed 50%, which is the standard for raw smoked sausages. The highest protein content (26.19%) was observed in sample 2, the amount of protein in other sausage samples exceeded the minimum recommended value of 19%. The fat content in all samples was in the range of 18.93-21.41%, which does not exceed the recommended standard of 25%. Based on the results of physical and chemical studies, the indicators were found to be in line with the established standards. Studies of changes in quality and safety indicators during storage determined the permissible shelf life of raw smoked fish sausages at temperatures from 0 to +5°C for no more than 15 days