bluuebunny/crossref_metadata_2025 huggingface dataset:
Potensi Enzim Mutanase yang Diisolasi dari Mikroba Tanah Gambut Paenibacillus soil Berbasis Tablet Effervescent sebagai Cleanser Plat Resin Akrilik di Bidang Kedokteran Gigi
Authors: Henadi Kim , Sukrama I Dewa Made , Mahendra Agung Nova
Published: September 2024

Acrylic resin plate is commonly used in dentistry as a frame for making dentures in prosthetics and removable appliances in orthodontics. It is a relatively biocompatible, comfortable, and cheap material. Just like natural teeth, if used in the oral cavity, it can also experience the accumulation of plaque, calculus, and bacteria. Therefore, acrylic resin plates also need to be cleaned to maintain sanitation. Standard cleansing methods are mechanical or chemical, whereas mechanical cleansing could cause abrasion, and chemical cleansing could cause corrosion and staining. Using an enzyme (mutanase) from Paenibacillus soil bacteria as effervescent tablets is an innovation to troubleshoot the drawbacks of the aforementioned cleansing techniques. Mutanase enzyme specifically hydrolyzes water-insoluble glucans 1-3-α-D-glucans bond from the calculus bacteria’s virulence, thus depriving its ability to adhere to the acrylic resin plate. The effervescent tablet will then release H2O2 and H2 ions while disintegrating to destroy the bacterial cell membrane through oxidation by H2O2 and dissolve the calculus deposit. This study aims to discuss the potential of mutanase from Paenibacillus soil in the form of effervescent tablets as a cleanser for acrylic resin plates.
 
Plat resin akrilik adalah material yang umum digunakan di bidang kedokteran gigi sebagai frame dalam pembuatan gigi palsu di bidang prostetik maupun alat lepasan di bidang orthodontik. Plat resin akrilik merupakan material yang relatif biokompatibel, nyaman, serta murah sehingga sangat umum digunakan. Sama seperti gigi asli, plat resin akrilik jika digunakan dalam rongga mulut juga dapat mengalami akumulasi plak, kalkulus, dan bakteri. Maka dari itu, plat resin akrilik juga perlu dijaga sanitasinya. Metode cleansing yang umum digunakan saat ini adalah secara mekanis atau kimiawi, namun cleansing mekanis dapat menyebabkan abrasi dan cleansing kimiawi dapat menyebabkan korosi dan staining. Cleansing dengan enzim (mutanase) bakteri batang Paenibacillus soil dalam bentuk sediaan tablet effervescent adalah sebuah inovasi yang berpotensi mengatasi kekurangan kedua metode cleansing tersebut. Paenibacillus soil merupakan bakteri yang didapat dari tanah gambut yang kaya akan mutanase aktif. Enzim mutanase spesifik menghidrolisis ikatan water-insoluble glucans 1-3-α-D-glucans dari virulensi bakteri kalkulus, menghilangkan kemampuan perlekatannya pada plat akrilik. Tablet effervescent akan melepaskan H2O2 dan ion H2 selama proses disintegrasi, yang mendestruksi membran sel bakteri melalui oksidasi oleh H2O2 dan melarutkan deposit kalkulus. Tujuan studi review ini adalah untuk mendiskusikan potensi penggunaan enzim mutanase dari Paenibacillus soil berupa sediaan tablet effervescent sebagai cleanser plat resin akrilik yang difungsikan di dalam rongga mulut.
Development of a method for inactivating lipoxygenases in linseed using chemical reagents
Authors: Belinska Anna , Ryshchenko Igor , Bliznjuk Olga , Masalitina Nataliia , Siedykh Kostiantyn , Zolotarova Svitlana , Fedak Natalia , Petrova Olena , Shevchuk Natalia , Danylchuk Galyna
Published: September 2024

The object of the study is the oxidative stability of the lipid component of linseed treated with a citric acid and sodium chloride solution. The rational composition of chemical reagents for inactivating linseed lipoxygenases was determined in the work. The obtained results make it possible to develop an effective linseed treatment method for increasing stability to oxidative spoilage. The proposed composition of the linseed treatment solution (citric acid – 1.0...1.3 %; sodium chloride – 0.6...0.8 %) significantly reduces the peroxide and anisidine numbers of the lipid component. This helps reduce oxidative spoilage during accelerated oxidation and storage under normal conditions. Rational treatment conditions were determined based on the approximate dependency of these indicators on the concentrations of chemical reagents. The data obtained in the work are explained by chemical interactions between the solution components and the enzyme complex of linseed, leading to enzyme denaturation and, accordingly, increased oxidative stability of the lipid component. A feature of the obtained results is the competitiveness of treated linseed, characterized by increased nutritional value due to improved technological properties. The results of the study allow minimizing the loss of nutritional value and increasing the shelf life of linseed products. The results are important for developing new oilseed processing technologies. This makes it possible not only to increase the stability of products against oxidative spoilage, but also to preserve their high nutritional value. Further research in this area will contribute to improving oilseed processing technologies, in particular linseed, which is an important contribution to the development of the food industry
Improving protection of falcon electronic signature software implementations against attacks based on floating point noise
Authors: Kachko Olena , Gorbenko Yurii , Kandii Serhii , Kaptol Yevhenii
Published: September 2024

The object of this study is digital signatures. The Falcon digital signature scheme is one of the finalists in the NIST post-quantum cryptography competition. Its distinctive feature is the use of floating-point arithmetic, which leads to the possibility of a key recovery attack with two non-matching signatures formed under special conditions. The work considers the task to improve the Falcon in order to prevent such attacks, as well as the use of fixed-point calculations instead of floating-point calculations in the Falcon scheme. The main results of the work are proposals for methods on improving Falcon's security against attacks based on the use of floating-point calculations. These methods for improving security differ from others in the use of fixed-point calculations with specific experimentally determined orders of magnitude in one case and proposals for modifying procedures during the execution of which the conditions for performing an attack on implementation level arise in the second case. As a result of the analysis, the probability of a successful attack on the recovery of the secret key for the reference implementation of the Falcon was clarified. Specific places in the code that make the attack possible have been localized and code modifications have been suggested that make the attack impossible. In addition, the necessary scale for fixed-point calculations was determined, at which it is possible to completely get rid of floating-point calculations. The results could be used to qualitatively improve the security of existing digital signatures. This will make it possible to design more reliable and secure information systems using digital signatures. In addition, the results could be implemented in existing systems to ensure their resistance to modern threats
Hemoglobin Purification Using His-Tag Affinity Chromatography With the Assistance of Ni Ions
Authors: Erkek Muhammed , Çalışır Merve , Topçu Aykut Arif , Denizli Adil
Published: September 2024

In this study, an affinity adsorbent of poly(2-hydroxyethyl methacrylate) [(p(HEMA)] was developed to purify hemoglobin (Hb). Initially, cryogel membranes of p(HEMA) were prepared and their surfaces were modified with the dopamine monomer to create polydopamine (pda) modified p(HEMA) cryogel [pda(HEMA)] membranes. After the modification, the nickel (Ni) ions were immobilized on pda(HEMA ) for Hb purification in the aqueous solution.
At pH 5, 23.5 mg/g Hb was adsorbed by the adsorbent and the Langmuir adsorption isotherm model was suitable for this adsorption process thanks to the R2 and q max values; moreover, the prepared adsorbent without notable decreases in its adsorption capacity
Postawy studentów wobec zjawiska infodemii w perspektywie doskonalenia edukacji medialnej w kształceniu akademickim
Authors:   Uniwersytet w Białymstoku, Polska, Borawska-Kalbarczyk Katarzyna
Published: September 2024

The article presents the results of a study that aimed to analyse students’ attitudes towards infodemic caused by the COVID-19 pandemic. The author adopted the interpretation of infodemic as a process of spreading an excess of untrue information, which complicates the evaluation and selection of reliable content. The research problem was the question of students’ attitudes towards false information related to the COVID-19 pandemic. The research sample consisted of 37 students of pedagogy. The research was conducted in a qualitative research paradigm. The results indicated that the surveyed students had a positive and stable organisation of their own knowledge, beliefs, feelings, and such forms of behaviour and expressive reactions as are necessary when confronted with infodemic. The respondents declared that they search for content in various sources and make a critical comparison and identification of false content. Despite this, they do not have a sufficiently in-depth knowledge of how to debunk false information. They feel the need for a great deal of cognitive effort to verify content. Therefore, the author makes recommendations for the formation of critical media literacy – as a way of building social resilience to disinformation and other disorders of the information age.
Filmowe wizerunki przestrzeni Donbasu po 2014 roku w wybranych filmach o tematyce wojennej
Authors:   Uniwersytet w Białymstoku, Polska, Adamski Tomasz
Published: September 2024

The paper aims to analyse the spatial representation in contemporary Ukrainian films created after 2014, set in the Donbas region and revolving around the ongoing war. As I reference the specific spatial context, my analysis is grounded in the framework of spatial turn. It also is crucial for me to delve into the history of Donbas and the portrayals of this place in Ukrainian cinematography. Film ecocriticism constitutes a significant context, particularly concerning representations of natural and postindustrial landscapes, often ravaged by human actions, especially in the context of warfare. Referring to the concept of landscape, I rely on Arnold Berleant’s perspective, noting that culturally transformed landscapes hold the same value as natural ones, and every landscape contributes to shaping cultural traditions. In my study, I employ textual film analysis derived from general structural analysis. My considerations encompass productions, such as Klondike (2022) directed by Maryna Er Gorbach, Reflection (2021) and Atlantis (2019), both directed by Valentyn Vasyanovych, as well as Bad Roads (2020) directed by Natalia Vorozhbyt.
II wojna światowa jako przyczyna zmian w podziale administracyjnym Kościoła katolickiego. Przykład diecezji Görlitz
Authors:   Uniwersytet Wrocławski, Pieniężny Dawid
Published: September 2024

War is a huge political change, which, in addition to its social, political, or economic effects, also has other effects. One of these may be the impact on churches and religious associations, especially on their organizational and administrative structures. An excellent example confirming this thesis is World War II, after which the organization of the Catholic Church in Europe was transformed and the Holy See revised the boundaries of archdioceses and dioceses in various countries for almost 50 years. In this article, the author addressed the specific case of the creation of the Diocese of Görlitz, which is the smallest diocese in modern Germany. Through his analysis he showed that the war has a huge impact on the functioning and efficient management in the Catholic Church and causes legal and interpretative difficulties in its administrative division and consequently, the division of competencies, while requiring delicacy, since strictly religious documents can be perceived in an explicitly political way.
The collapse of life plans; paradoxes of combination of historical personality (based on the novel by L. Feuchtwanger “The Ugly Duchess Margarita Maultasch”)
Authors:   Baku Slavic University, Azerbaijan, Rzayeva Sevinj
Published: September 2024

Lion Feuchtwanger is known mainly as the creator of historical novels and voluminous epic canvases. However, all his thoughts are directed to the future. With a certain reservation, we can say that he tried on the past to the realities of his time. Until his death, he was concerned with the key question: what are the paths, prospects and main driving forces of events distant from the 20th century in visual comparison with those changes in German society, which he directly witnessed. In a narrow sense, these were the writer’s attempts to resolve the “damned issues” concerning his own nation. In broad terms – philosophical reflections on the fate of humanity. Thus, his work objectively went beyond the national framework, enriching itself with universal and deeply humanistic content.
Armed Conflict as an ‘Undoing’ Force in Regional Integration and Its Impact on the Consolidation of AfCFTA Development Mission
Authors:   University of Warsaw (Poland), Shumba Munyayiwashe
Published: September 2024

The paper examines the intricate relationship between armed conflict and regional integration, focusing on its role as an ‘undoing’ force in the African Continental Free Trade Area (AfCFTA) context. A significant element of development and economic cooperation in Africa is the perennial problem of violent conflict in almost all sub-regions. Moreover, organized crime is rising across the continent, coupled with the emergence of new forms of violence associated with today’s globalization and other post-Cold War phenomena. Globalization has led to greater interdependence among countries and fostered cooperation among states. However, a country’s internal conflict often has repercussions beyond its borders and threatens regional and global peace and stability. In addition, armed conflict can affect countries’ relations and state cooperation. Peace provides a good foundation for development and economic cooperation, while development ensures the permanence of peace. The central question addressed in this paper is whether constructive regional economic integration and cooperation can be effectively achieved while some African countries are experiencing armed conflict. A qualitative research approach is used to analyze how armed conflict will likely negatively impact the achievement of AfCFTA goals.
Safety Issues of the Rail Transport System in Poland during COVID-19: A Review Based on Statistics and Research
Authors:   Military University of Technology (Poland), Nowacki Gabriel , Jaworska Karolina ,   Internal Security Agency (Poland)
Published: September 2024

The paper presents the characteristics of the rail transport system, including passenger and freight transport during the Covid-19 pandemic. The entities responsible for the safety of the railway sector were presented, among which were the Railway Transport Office, the company PKP PLK S.A., and the Railroad Security Guard, which played the most critical role. The paper presents statistical data for railway accidents and casualties in 2018–2021. It was noted that the Covid-19 pandemic significantly reduced passenger and freight transport. 2021 was the European Year of Railways; it was also an exceptional, demanding, and significant year for changes taking place on the railways. Throughout this time, the Office of Rail Transport promoted rail as a safe, ecological, and comfortable means of transport. Based on statistics and empirical research, the main problems of the railway sector were discussed, and the research hypothesis was verified positively.
STUDY ON CHANGES IN PORE SIZE ON SINGLE POWDER AND REDUCTION SWELLING INDEX DURING THE REDUCTION OF IRON MILL SCALE WITH HYDROGEN AND FORMING GAS
Authors: Paizullakhonov Mukhammad Sultonkhon , Abduraimov Sanjar , Kovtun Oleksandr , Volkova O. , Abduraimov Samar
Published: September 2024

In this research study, we examined the impact of hydrogen content, temperature, and reaction time in reducing the mill scale and porosity formation on a single powder. Reduction reactions were carried out at temperatures ranging from 700°C to 1000°C under hydrogen and forming gas
(80 vol% N2/20 vol% H2). The utilization of hydrogen as a reducing agent has been identified as leading embrittlement and the creation of porous configurations. In this study, we examined the porosity structures on the single powder formed during the reduction of iron oxides using two different reducing gases. The results indicated an increase in the degree of reduction and porosity size on the single powder with increasing temperature for both hydrogen and hydrogen/nitrogen mixtures.
OTİZM SPEKTRUM BOZUKLUĞU TANISI OLAN ÇOCUKLARIN ANNELERİNİN ALGILADIKLARI SOSYAL DESTEK VE PSİKOLOJİK SIKINTI DÜZEYLERİNİN İNCELENMESİ
Authors: Yorulmaz Elçin , Dirik Gülay , Yıldırım Muazzez
Published: September 2024

Otizm Spektrum Bozukluğu (OSB) yaygınlığı yıllar içerisinde artarak hem tanı alan bireyi hem de ailesini etkileyen bir rahatsızlıktır. Ebeveynlerin süreçte stres yaşadıkları, depresyon ve anksiyete rapor ettikleri görülmektedir. Bu çalışmada OSB tanılı çocuğu olan annelerin psikolojik sıkıntı düzeyleri, bu sıkıntılar ile algılanan sosyal desteğin (ASD) ilişkisi ve stresin depresyon üzerindeki etkilerinde ASD’nin koruyucu rolünün incelenmesi amaçlanmıştır. Bu amacı gerçekleştirmek için çalışmaya çocuğu OSB tanısı almış 156 anne katılmıştır. Katılımcılara Demografik Bilgi Formu, Depresyon Anksiyete Stres 21 Ölçeği (DASS-21) ve Çok Boyutlu Algılanan Sosyal Destek Ölçeği (MSPSS) uygulanmıştır. Araştırmanın sonucunda, stres, depresyon ve anksiyetenin pozitif ilişkileri olduğu bulunurken, ASD’nin ve farklı kaynaklardan ASD’nin de bu belirtilerle ilişkileri incelenmiştir. Yalnızca özel birinden ASD depresyon ile negatif ilişkili olarak bulunmuştur. Ayrıca, stres ve depresyon ilişkisinde ASD’nin ve farklı kaynaklardan ASD’nin düzenleyici rolüne ilişkin hipotezler desteklenmemiştir. Sonuç olarak, ASD’nin stresin depresyon üzerindeki etkilerinde koruyucu rolünün olmadığı sonucuna ulaşılmıştır. Alanyazın bağlamında da çelişkili bulguların olduğu görülürken, OSB tanılı çocuğu olan anneler açısından sosyal desteğe dair algılarının, beklentilerinin değerlendirilmesinin fayda sağlayacağı düşünülmektedir. Son olarak, çalışmanın kısıtlılıkları ve gelecek çalışmalar için öneriler yer almaktadır.
DIGITAL SOLUTION FOR OPTIMIZATION OF FORMATION TESTING DESIGN
Authors: Mihailov D.N. , Knyazev E.I. , Borodin I.V. , Blinov V.A. , Dzhalatyan Y.E. , Ramazanov U.S.
Published: September 2024

Evaluation of pumping time to receive a clean sample during fluid sampling job with wireline formation tester as well as evaluation of pumping scenarios to minimize sampling duration under existing constrains (reservoir and sandface constrains, safety etc.) are actual problems especially for fluid sampling in low-permeability formation. The article describes the digital solution allowing to simulate mud filtrate invasion in near-wellbore zone during well drilling and mud filtrate displacement by reservoir fluid during fluid sampling job with taking into account a formation damage dynamics. In this way, the software is able to evaluate depth of mud filtrate invasion and simulate both the multiphase inflow dynamics and the skin-factor dynamics during sampling job and predict sampling duration. To take into account a complex, essentially non-1D geometry of multiphase fluid flow in near-wellbore zone during fluid sampling, the special upscaling technique was developed. This upscaling technique is based on modification of 1D model by introduction of «effective» mud filtrate invasion profile and «geometry factor» which depend on ratio of vertical to horizontal permeabilities. The correlations between empirical model parameters and ratio of vertical to horizontal permeabilities were obtained by matching results of «pseudo 2D» simulations of pumping dynamics with results of 2D / 3D simulations conducted using commercial simulators ECLIPSE® and COMSOL Multiphysics®. The developed «pseudo 2D» model is computationally fast ones that allows to effectively conduct sensitivity study as well as adjust the model parameters and sampling scenario in real time in accordance with the real-time wireline formation tester measurements.
I Am Cringe, But I Am Free: Cringe on Its Way From Self-Identity to Liberation
Authors:   Institute of Philosophy, St. Petersburg State University, Russia, Neapolitanskiy Maximilian
Published: September 2024

The article proposes an aesthetic and political understanding of the phenomenon of cringe as a particular form of feeling. The thesis posits that cringe can be defined as an aesthetic regime that changes the coordinates of habitual affects — primarily shame. The article refers to the ideas of Jacques Rancière presented in The Aesthetic Unconscious. It helps to analyse cringe through the problem of overcoming hierarchies and self-identity and also to see cringe as an affect that arises at the boundaries of personal and collective experience, linked to the altered figure of the Other. As an aesthetic regime, cringe allows for the expansion of the field of questions and touches on epistemological issues. In this regard, the article refers to Donna Haraway’s concepts of “god trick” and “situatedness.” Based on the latter, the author defines the cringe state as a lack of situatedness, associated with a refusal of reflection and a reluctance to discover the limits of the foundations of thought. To understand the political dimension of cringe, particular attention is focused on the ambivalence of the processes involved in the correlation of cringe and power relations. The author provides characteristics of two trajectories — alienation and liberation. This conceptual move allows cringe to be inserted into the tradition of counterculture and expands the understanding of the totality of its presence. The latter makes it possible to argue that the art of life and the art of the self is an art of being cringe, which enables seeing the cringe in a space of equality that cannot be normalised. It is concluded that cringe moves from a marginal affect to a mode of political feeling that involves psychoanalytic discourse and various bodily and emancipatory practices.
Heptane preparation of Annonaceae pollen v1
Authors: LP Thomas Couvreur , Chaowasku Tanawat , W. J. M. van der Ham Raymond
Published: September 2024

The protocol used to study Annonaceae pollen taken from herbarium dried specimens or in field alcohol conserved material. The protocol deviates from previous versions by using Heptane instead of n-Hexane.
RNA purification and cDNA synthesis v1
Authors: Deng Vicki , leon Fredrick , Booth David
Published: September 2024

This protocol compiles multiple methods for purifying RNA from an S. rosetta lysate and provides a modified reverse transcriptase protocol to robustly synthesize cDNA from transcripts with higher GC content.
Pan-microbial metagenomics protocol v1
Authors: Alcolea-Medina Adela , Blagdon Snell Luke , Alder Chris , Batra Rahul
Published: September 2024

DOI: 10.1038/s43856-024-00554-3
PENGARUH PENERAPAN MODEL PEMBELAJARAN REACT TERHADAP HASIL BELAJAR SISWA KELAS 6 SD NEGERI 10 SUNGAI SAPIH KURANJI
Authors: Fitriani Kintan , Rahmi Ulfia
Published: September 2024

The research is based on the problem that the researcher found in grade 6 of SDN 10 Sungai Sapih Padang where student learning outcomes are very low in PKN subjects in the material of socio-cultural and economic diversity due to various factors. The researcher decided to implement the REACT learning model in order to improve the learning outcomes of students in the 6th grade.This study is a quasi-experimental study with class 6B as the experimental class and class 6C as the control class. The procedure is preparation, research and assessment. The technique of collecting data in this research is a test in the form of objective questions, as well as documentation with the instrument, namely test items. The tests used are normality, homogeneity and independent.Based on the analysis, it was found that there were differences in learning outcomes between classes taught with the REACT and conventional models in PKN subjects on socio-cultural and economic diversity. with the difference in the final score, namely in the experimental class the average value is 82, the highest score is 100 and the lowest is 50, while the control class has an average value of 7, the highest score is 90 and the lowest is 55. So it can be seen if there is a significant difference which can also be seen from the test results. the hypothesis obtained 0.05 (Sig. 0.000 0.05) means that Ha is accepted. The conclusion is that there are differences in the learning outcomes of students who study with the REACT learning model and students who study conventionally on PKN subjects in the socio-cultural and economic diversity of SDN 10 Sungai Sapih Kuranji.
Evaluation of The Implementation of The Computer Based National Assessment in Indonesian School of Bangkok
Authors: Qomariah Nurul , Sumardi Sumardi , Muhibbin Ahmad
Published: September 2024

Starting with the final-stage assessment system for basic and secondary schools, problems continue to arise during the final stage of assessment. In addition, as Indonesia is affected by the COVID-19 pandemic, the problem requires learning activities to be implemented online. Starting in 2020, the Ministry of Education and Culture will transform the National Exam into a national computer-based assessment or Asesmen Nasional Berbasis Komputer (ANBK). This change shows a paradigm in the evaluation of primary and secondary education. The study was conducted at Indonesian School of Bangkok, Indonesian School Overseas located in Bangkok, Thailand. The aim of this study is to identify, describe, and formulate the evaluation of the implementation of ANBK at the primary school of Indonesian School of Bangkok. This study is expected to be used as a reference in the implementation of ANBK in the next year. This research method is qualitative descriptive in which data is obtained through active observation, open interviews, and documentation. The results of the research showed that the implementation of the ANBK at the Indonesian School of Bangkok went with the lancer despite several obstacles, including technical constraints and the level of concentration of students in working on the issue of the ANBK. The observation results also showed that there are students with a marriage background of citizens of Indonesia and foreign nationals  parents who reach the minimum limits of competence in literacy and numeration aspects, but character aspects have evolved.
Pengembangan Lembar Kerja Peserta Didik (LKPD) Digital Berbantu Canva untuk Mengembangkan Numerasi Peserta Didik
Authors: Laela Nur , Alamsyah Trian Pamungkas , Pamungkas Aan Subhan
Published: September 2024

Penelitian ini bertujuan untuk mengembangkan lembar kerja peserta didik (LKPD) digital berbantu canva untuk mengetahui kemampuan numerasi peserta didik. Penelitian ini menggunakan metode RD yang menggunakan model 4-D melalui 4 tahap, yaitu tahap pendefinisian (define), tahap perencanaan (design), tahap pengembangan (development) dan tahap penyebaran (disseminate). Subjek dalam penelitian ini adalah kelas IV SDN Cibadak 2. Teknik pengumpulan data dan informasi seperti Test Numerasi, wawancara, observasi, angket dan dokumentasi. Instrumen yang digunakan untuk mengukur kelayakan LKPD ini yaitu angket validasi yang terdiri dari ahli media, ahli materi, dan ahli bahasa, angket respon peserta didik, dan test kemampuan numerasi. Berdasarkan angket validasi ahli didapatkan hasil yaitu ahli media mendapatkan skor persentase ratarata 79,1% dengan kriteria layak, penilaian ahli materi mendapatkan skor persentase rata-rata 89,3% dengan kriteria sangat layak, dan penilaian ahli bahasa mendapatkan skor persentase rata-rata 77% dengan kriteria layak. Adapun hasil angket respon peserta didik mendapatkan skor presentase 94,7% dengan kategori sangat baik. Sedangkan hasil test menunjukan skor pencapian kemampuan numerasi sebesar 64% dengan kriteria baik. berdasarkan hasil analisis dapat disimpulkan bahwa lembar kerja peserta didik yang dikembangkan layak dan praktis digunakan sebagai bahan ajar dalam mengembangkan numerasi peserta didik pada pelajaran matematika SD.
Unestablished Boundaries: The Capabilities of Immersive Technologies to Induce Empathy, Tell Stories, and Immerse
Authors: Kukshinov Eugene
Published: September 2024

This article presents a critical viewpoint on the existing research to establish the boundaries of immersive technologies, such as virtual reality, exploring distinctions between sensorial and mental experiences and highlighting the influence of technological determinism in this scholarly domain. The analysis reveals a lack of established conceptual structures for categorizing distinct types of immersion, emphasizing that immersion is not universal and is not inherently technological. In particular, it highlights that, fundamentally, immersive technologies are not designed to immerse into narratives. As a result, this article suggests a dual cognitive framework of immersion to explain the nature of different immersive experiences. The article also critically addresses ethical concerns related to identity tourism and argues against the oversimplification of complex psychological processes, emphasizing the overreliance of the existing studies on visual or technological stimuli. To avoid this, the article suggests a way to avoid technological determinism in relevant conceptualizations. Overall, the article scrutinizes the assumptions associated with immersive technologies, offering insights into their capabilities to stimulate senses and vividly inform, contributing to a nuanced understanding of their effects and ethical implications.
Displacement and Everyday Resistance: Seeking Spatial Justice in Urban Renewal Processes
Authors: Juhila Kirsi , Perälä Riikka
Published: September 2024

This study focuses on four housing displacement cases in which residents were forced to move from their homes and neighbourhoods. The data contain interviews with 39 displaced residents. We ask how the residents sought spatial urban justice in resisting their displacement. In analysing the data, we apply the concept of “everyday resistance” complemented with an understanding of resistance as discursive counter‐speech to various injustices experienced in the displacement processes. The results demonstrate that even if resistance is not collective or publicly visible, this does not mean that it does not exist. We located four repertoires of resistance in the interviews: reflective, emotional, rejective, and face‐to‐face. Through them, the residents questioned the processes of displacement and their consequences, identified power relations related to their displacement in the urban renewal processes and reacted to them, and, by doing so, tried to seek spatial justice for themselves.
Peran Komite Audit terhadap Fraudulent Financial Reporting
Authors: Kusumawardani Media , Soediro Achmad , Adhitama Fardinant
Published: September 2024

Latar Belakang: Kegiatan fraudulent financial reporting merupakan tindakan penipuan yang sering dilakukan. Kecurangan pelaporan keuangan menimbulkan banyak kerugian bagi beberapa pihak. Penelitian ini dilakukan untuk mencari faktor-faktor yang dapat mengurangi kecurangan pelaporan keuangan. Salah satu faktor yang ingin diuji adalah komite audit. Penelitian ini menguji komponen komite audit (size, expertise, meet, gender diversity) pada kecurangan laporan keuangan (fraudulent financial reporting).Tujuan: Tujuan penelitian ini adalah untuk menguji pengaruh komite audit khususnya variabel komite audit (size), komite audit (expertise), komite audit (meet), komite audit (gender diversity) terhadap fraudulent financial reporting.Metode Penelitian: Jenis penelitian ini adalah kuantitatif dan menggunakan data sekunder laporan keuangan perusahaan manufaktur tahun 2018-2021. Populasi penelitian adalah perusahaan manufaktur pada Bursa Efek Indonesia tahun 2018-2021. Sampel penelitian menggunakan metode purposive sampling yang menghasilkan sampel sejumlah 492. Analisis penelitian yang digunakan adalah analisis regresi logistik. Hasil Penelitian: komite audit (expertise) yang menggambarkan keahlian komite audit terbukti mempunyai pengaruh negatif terhadap fraudulent financial reporting, sedangkan komite audit (size, meet, gender diversity) tidak mempunyai pengaruh terhadap fraudulent financial reporting.Keaslian/Kebaruan Penelitian: memasukkan variabel gender diversity (komite audit) dalam menguji dampak perempuan pada komite audit pada fraudulent financial reporting yang diukur menggunakan jumlah perempuan yang terlibat pada anggota tim komite audit, sedangkan penelitian sebelumnya menggunakan pengukuran dummy. Kebaharuan lain pada penelitian ini adalah menguji komponen komite audit size, expertise, meet dan gender diversity dalam satu model penelitian fraudulent financial reporting.
Variants in the superior attachment of uncinated process and their corresponding frontal sinus drainage pattern: a computed tomography-based retrospective clinical study
Authors: M. G. A. Visali , Ravichandran Praveen , Balasubramani Naveen Kumar , Ayyadurai Saranya
Published: September 2024

Background: Understanding the morphology and spatial relationships of the uncinate process and its associated spaces is crucial for diagnosing and treating conditions affecting sinus drainage and ventilation. This consistent anatomical structure is an important surgical landmark for endoscopic sinus surgery.
Methods: Computed tomography (CT) records of 100 patients over two years were extracted via the hospital's PACS system. The type of superior insertion of uncinate process (UP) was observed in coronal cuts of CT scan images, and classification was done based on the Friedmann and Landsberg classification system and tabulated. The corresponding variations in the frontal sinus outflow tract were noticed, and their effect on frontal sinusitis was recorded. Sinusitis of the frontal sinus was in guidance with EPOS 2020 (mucosal changes within the ostiomeatal complex or sinus).  
Results: Type 2 was the most common of uncinate attachments (39.5%). The least common variant was type 5 (4%). Medial-type frontal sinus drainage pathway was observed in 78.5% of patients. Sinusitis was present in 23.5% of our study population. Type 2 had a 25% contribution to the occurrence of sinusitis. The medial frontal sinus drainage pathway contributes 24% to sinusitis with a significant p value of 0.010.
Conclusions: Uncinate process, with its varying superior attachment, influences the frontal sinus outflow tract and may contribute to the development of frontal sinusitis. Awareness of the possible variations in the attachment of the uncinate process is vital in the preoperative planning process, which will serve as a road map to surgeons and aid in preparedness for intraoperative complications.
Evaluating treatments for male androgenetic alopecia: clinical profile and comparative efficacy of platelet rich plasma and minoxidil with finasteride
Authors: Gupta Mehak , Garg V. K.
Published: September 2024

Background: Androgenetic alopecia (AGA) is a common, hereditary, and androgen-dependent disorder characterized by progressive hair thinning on the scalp, affecting both men and women. It arises from follicular miniaturization, leading to the conversion of terminal hair into vellus hair.
Methods: This study is a single-center, prospective, open-label, randomized, placebo-controlled trial with four parallel arms designed to evaluate treatments for male pattern baldness. Eighty patients were randomized into four groups: Group 1 received topical minoxidil and finasteride solution, group 2 received PRP alone, group 3 received PRP with minoxidil and finasteride solution, and group 4 received normal saline (NS). Interventions were administered monthly over three months, followed by a three-month follow-up period. Treatment effects were assessed using measures such as patient self-assessment, global photography, and the hair pull test.
Results: Group 3 (combined treatment) showed the most significant improvement in the hair pull test after six months (73.33% negative tests), followed by group 2 (PRP treatment) with 60% improvement. Patient satisfaction scores were highest in group 3 across all follow-ups (F1 to F5), demonstrating superior treatment response compared to other groups (p<0.001). Global photography assessments indicated varying results among groups, with group 4 recording the highest proportion of fair improvements (58.5%). Group 3 exhibited the highest percentage of patients with above-average improvement.
Conclusions: Our study provides valuable insights into managing AGA, emphasizing the effectiveness of combining PRP with topical treatments compared to individual therapies and placebo.
The Development of Math Learning Media: 3-Dimensional Snake and Ladder
Authors: Chusna Puji Asmaul , Inayati Isna Nurul , Santoso M. Jamal Hadi
Published: September 2024

This article is motivated by the lack of mathematics learning media at Islamic primary education, which has an impact on the low motivation of students to learn the subject. To solve these problems, the development of three-dimensional snakes and ladders is an interesting thing to do. In order to develop the media and measure the feasibility of 3D snakes and ladders learning media in the mathematics subject matter of counting operations of whole numbers, this research is to be carried out. The research method used is research and development using the Borg & Gall model, which is composed of five stages that have been limited. The research subjects were homeroom teachers and fourth grade students at MI Miftaul Huda Kanigoro Blitar. By conducting validation tests with media experts, materials, math teachers, and students. So that the percentage of feasibility of material experts (79.3%) with the predicate "valid" is not revised, media experts (94.1%) with the predicate "very valid" is not revised, math teachers (92.8%) with the predicate "very valid" is not revised, and the increase in learning outcomes reaches 90%. So it is concluded that the learning media for the 3D snakes and ladders game of counting operations for small numbers reaches a value of more than 68%; therefore, it can be stated that the media is relevant or suitable for use.
The Effects of Cognitive Flexibility on Teacher’s Readiness To Implement the Merdeka Curriculum
Authors: Idawati Idawati , Akrom Abdul Hayyi , Asy’ari M. Hasanil
Published: September 2024

This article aims to determine cognitive flexibility in influencing teacher readiness for implementing the "imerdeka curriculum" in schools. Research method used a regression test using comprehension survey data using a questionnaire to see differences in the level of teacher readiness in implementing the "merdekat curriculum" based on high and low levels of teacher cognitive flexibility. The research subjects were 30 teachers of MI (Islamic Elementary School) in NW Dasan Lekong, Sukamulia Regency, and MI Hamzanwadi Toya, Aikmel Regency, two private schools in East Lombok, West Nusa Tenggara, Indonesia. The research results show that teachers' cognitive flexibility abilities have a significant effect on teachers' readiness to implement the "Independent Curriculum" in schools. This can be seen from the significance score of 0.000, which is less than 0.05, so it can be concluded that teachers with high cognitive flexibility are better prepared to implement the Merdeka Curriculum in schools than teachers with low cognitive flexibility.
Doğada “Yüce” Kavramının C. David Friedrich’ in Eserlerinde Estetik ve Felsefi Yansımaları
Authors: Ünal Burçin
Published: September 2024

Yüce kavramı, belirli bir olumsuz veya tanımlanamayan duygunun haz yoğunluğuyla ilişkili, ölçülemezliği ile aklın sınırlarını aşan ve algılama/kavrama yetisini kısmî zamanlı duraklatan nesne ya da durumlarla karşılaşma ile ortaya çıkan dönüştürücü bir deneyimi tanımlar.
Bu makalede, estetik bir değer olan ‘Yüce’ kavramı, Edmund Burke ve Immanuel Kant’ın doğada yücenin duyumsanması ve kritiği bağlamında ele alınmaktadır. Burke ve Kant’ın, yüce üzerine değerlendirmelerine paralel şekilde, sanatta yücelik temsilinin güçlü örneklerini oluşturan Romantizm ressamlarından Caspar David Friedrich’in eserleri; doğada ‘yüce estetiği’ nin açımlanması ve etkileşimleri çerçevesinde irdelenerek, değerlendirilmektedir.
Mehmed Siyah Kalem'in Eserlerinde Şamanizm İzleri
Authors: Can Ramazan
Published: September 2024

Şamanizm, onu uygulama yeteneğine sahip literatür adıyla Şaman asıl adıyla Kam’ın trans halini yakalayarak bilinen maddi dünyanın ötesinde cinler, ruhlar ve doğa üstü yaratıklara ait dünyayla irtibat kurabildiğine inanılan bir inanç sistemidir. Kurulan bu iletişimin ana amacı doğaüstü güçlerin enerjilerini fiziksel dünyaya yönlendirerek onlardan şifa, kehanet vb. gibi yardımlar almaktır. Büyü ve tılsımın ortaya çıktığı andan itibaren varlığından söz edilen bu inanç sistemi Türklerin ve çevresindeki halkların yaşam şekli haline gelmiş ve dolayısıyla onların sanat anlayışını etkilemiştir. İslamiyet’in kabulünden sonra da bir şekilde varlığını devam ettiren bu anlayışın Mehmed Siyah Kalem gibi dönem sanatçılarının eserlerinde izlerini görmek mümkündür. Bu araştırma Topkapı Sarayı Müzesinde yer alan 2153 numaralı albümün içinde yer alan Mehmed Siyah Kalem’e ait eserlerde Şamanizm etkilerini saptamak amacıyla yapılmıştır.
Validation study of Hba1c kit to be used in diabetic population
Authors: Özkan Elife
Published: September 2024

Amaç: Hastaneye başvuran Diyabetes Mellitüs tanılı hastalarda taramada kullanılacak olan HbA1c kiti doğrulama çalışması
Gereç ve Yöntemler: Rutin analizlerde kullanılan HbA1c kiti internal ve external kontrolleri yanısıra laboratuvar içi doğrulama validasyon çalışmaları testin geçerli kılma basamakları, doğruluk (accuracy) Kesinlik (presizyon) ve rapor aralığı işlemleri yapılmıştır.
Sonuç: Hastane tıbbi laboratuvarında HbA1c kitinin bu doğrulama ve geçerli kılma işlemlerini tüm basamakları yapılmış ve kayıt altına alınmıştır. Çalışmalar arası tekrarlanabilirlik (%CV) 0.88, Yöntem / referans materyali karşılaştırma (% Bias) 3.94 Hedef: (% Bias + 1.65 (%CV) < TEa) Sonuç olarak TAH:5,40< TEa:18 (rilibak) olarak hesaplanmıştır ve kit verifiye olmuştur. Diyabetik popülasyon taramasında kullanılacak olan kitin doğruluğu maliyetli ve yaygın bir hastalığın tedavi ve takibinde klinisyen öngörüsünü etkileyeceği için önemlidir.Tüm laboratuvarlar ticari kit olsun olmasın doğrulama işlemlerini laboratuvar güvenirliğini ve kalitesini artırmak adına yapmalıdır. Özellikle toplumu etkileyecek hastalıkların analizlerinde klinisyenlere doğru yön vermek adına yapılması zorunlu olmalıdır. Geniş popülasyonu etkileyecek uzun süreli çalışmalarda kullanılacak kitin doğrulama verilerinin araştırma verilerine eklenmesi de çalışmanın etkinliğini artıracaktır.
Asemptomatik hiperüriseminin hidradenitis süppürativa hastalık seyrine etkileri
Authors: Karstarlı Özge Sevil , Bakay Umut
Published: September 2024

Amaç: Hidradenitis süppürativa (HS) hastaların hayat kalitesini belirgin olarak etkileyen ağrılı abse ve nodüller, sinus traktüsleri ve skarlarla karakterize kronik inflamatuar bir hastalıktır. Hastalığa metabolik sendrom, kardiyovasküler hastalıklar ve artrit gibi komorbiditeler eşlik etmektedir. Asemptomatik hiperüriseminin sıklığı günümüzde giderek artmaktadır ve inflamasyonu şiddetlendirdiğine dair veriler mevcuttur. Bu çalışmada hiperüriseminin HS hastalarında hastalık şiddeti, klinik ve laboratuvar bulgularıyla ilişkisini incelemeyi amaçladık.
Gereç ve Yöntemler: Bu kesitsel çalışmaya Pamukkale Üniversitesi dermatoloji kliniğinde HS tanısı alan hastaların yanı sıra beden kitle indeksi (BKİ), yaş, cinsiyet açısından benzer nitelikte olan, inflamatuar dermatolojik hastalığı olmayan gönüllüler dahil edildi. Serum ürik asit (SÜA), C-reaktif protein (CRP), açlık glukoz, yüksek yoğunluklu lipoprotein kolesterol (HDL), total kolesterol ve trigliserid değerleri kaydedildi. Hastalık şiddetinin belirlenmesi için Hurley sınıflaması ve Uluslararası Hidradenitis Suppurativa Şiddet Skorlaması (IHS4) kullanıldı. Tüm hastalara dermatoloji yaşam kalite indeksi (DYKİ) uygulanarak hastalığın hayat kaliteleri üzerine etkisi incelendi.
Bulgular: Çalışmaya 53 HS tanılı hasta, 44 gönüllü dahil edildi. HS hastalarının 23’ünde (%43.4) hiperürisemi mevcuttu. Hastaların ortalama SÜA seviyeleri, kontrol grubundan yüksek olarak saptandı (6.4±1.4 mg/dL, 4.8±1.4 mg/dL, sırasıyla p
A comparative study on germination of wheat grains with different anthocyanin pigmentation of the pericarp in natural or induced aging
Authors: Gordeeva E. I. , Shoeva O. Y. , Khlestkina E. K.
Published: September 2024

One of promising areas of wheat breeding is the creation of varieties with a high concentration of anthocyanins in the grain for the production of functional food products. Nonetheless, the question of how these compounds aﬀect seed viability after long-term storage has remained unexplored. A comparative study on seed viability was conducted using a set of near-isogenic lines on the background of spring wheat variety Saratovskaya 29. These sister lines carry diﬀerent combinations of recombinant DNA regions (on chromosomes 2A and 7D) containing dominant and recessive alleles at loci Pp3 and Pp-D1 (Pp: Purple pericarp), which determine the anthocyanin color of coleoptiles and of the pericarp. Seeds were germinated on two layers of water-moistened filter paper in a climatic chamber at a constant temperature of 20 °C on a 12-hour daylight cycle. During long-term natural storage of the seeds for up to 9 years in a dry ventilated room in Kraft bags at 20 ± 2 °C, the tested wheat samples experienced a loss of seed germination capacity of ~50 %; anthocyanins were found to not participate in the preservation of germination capacity. Nonetheless, anthocyanins contributed to the preservation of seed viability under unfavorable short-term conditions of a temperature rise to 48 °C at 100 % humidity. The accelerated aging test did not predict poor germination capacity after long-term seed storage. The results showed a neutral role of anthocyanins in the maintenance of seed germination capacity for 6–9 years under natural storage conditions at 20 ± 2 °C. A small statistically significant increase in grain germination capacity during natural aging was associated with the presence of a recombinant region containing the Pp-D1 gene on wheat chromosome 7D.
Major Adverse Cardiac Events and Mortality Associated With Electroconvulsive Therapy: Correcting and Updating a 2019 Meta-Analysis
Authors: Read John
Published: September 2024

This article updates a 2019 review of the research about the incidence of major cardiac events following electroconvulsive therapy (ECT), and critiques claim that these are rare and, therefore, inconsequential. It concludes that the 2019 review misrepresents its own findings which were, anyway, based on a rather obvious miscalculation of the probability of cardiac events. Having corrected the review, and updated it with five subsequent studies, it is calculated that the probability of ECT causing one or more of six cardiac events (myocardial infarction, life-threatening arrhythmia, acute pulmonary edema, pulmonary embolism, acute heart failure, and cardiac arrest) is between 1 in 15 and 1 in 30 patients and that these cardiac events are a major cause of ECT-related deaths. The ethical principle of informed consent is being routinely breached by ECT psychiatrists.