bluuebunny/crossref_metadata_2025 huggingface dataset:
Aggregate Mixtures for Least-Void Content for Use in Polymer Concrete
Authors: Kantha Rao VVL , Krishnamoothy S
Published: February 2024

Over 350 mixtures of quartzite aggregate with locally available pit sands have been made in the laboratory, and the proportions of fine aggregate for 34 least-void content mixtures have been obtained experimentally. Plots have been made between the proportion of aggregate fraction finer than largest size fraction and the fineness modulus of such a fraction. The proportions required for least-void content followed a linear trend fairly similar to what one would obtain from the theoretical gradings of Fuller, Weymouth, or Ehrenberg, but the actual proportions of fine fractions were somewhat lower than those obtained from such hypotheses. Reasons for the difference are discussed.

An empirical equation has been fitted for this linear trend so that it can be used to determine the proportions of coarse and fine aggregates of least-void contents. Based upon Powers' modification of Butcher's and Hopkins' equation, the nature of particle interference in aggregate mixtures has been discussed. The experiments have also shown that use of gap-graded or sands of restricted sieve sizes results in reduced particle interference when compared with using fine aggregates of continuous grading, even though aggregate mixtures having gap-graded fine aggregates may have slightly higher values of void ratio.

The experiments were extended to study the optimum microfilier content needed to fill some of the remaining voids of the system. The amount of microfilier that can be used before further particle interference takes place is obtained by one of the three methods suggested, including the use of Powers' equation as modified in this work.

Mixtures of coarse and fine aggregates and microfilier with least possible void ratios are preferred for making polymer (resin) concretes.
Soil Stress Gage Calibration
Authors: Selig ET
Published: February 2024

Interpretation of field measurements of stress in soil using embedded gages requires proper calibration and a knowledge of the performance of the gages in soil. This paper describes an easy-to-construct and inexpensive fluid calibration chamber for soil stress gages. A suggested soil calibration facility is also described. Examples of calibration results are given to illustrate the type of information that can be obtained.
Modern Electronics for Geotechnical Engineers 6. Process Control Applications
Authors: Moore CA
Published: February 2024

Principles of process control for geotechnical engineering applications are described. Detailed circuits are given for a servopneumatic control module.
Fracture Mechanics Expressions for the Standard Chord-Supported Arc Bend Specimen
Authors: Tarafder S , Tarafder M , Ranganath VR
Published: February 2024

The linear-elastic deformation behavior of the standard chord-supported arc bend, A(B)-C, specimen has been modeled using the finite element method (FEM) in order to generate displacement and compliance data for wide ranges of geometric variables. Using these data, stress intensity factor (SIF) expressions, and crack mouth compliance (CMC) and compliance crack length (CCL) relations have been developed for the A(B)-C geometry. The accuracies of the developed fracture mechanics expressions have been determined with respect to the FEM data and were found to be within ±0.75% maximum. Against data and expressions available in the literature, the accuracies of the developed relations were evaluated and found to be satisfactory.
Minimum Thickness Requirements for Rockwell Hardness Testing
Authors: Heberling TG , Fee AR , Tobolski EL
Published: February 2024

A study was performed in an attempt to resolve the conflicting thickness requirements for Rockwell hardness testing specified in ASTM Standard Test Methods E 18-93 and in ISO Standard 6508. Commercial standardized hardness test blocks were machined to “steps” of various thicknesses using a wire EDM (electrical discharge machining) process. Rockwell hardness tests were performed on the original standardized surface of these “stepped” blocks in an attempt to determine the minimum thicknesses required for reliable Rockwell hardness testing. The extremes of test force and hardness were investigated for both the diamond brale and 1/16 in. (1.588 mm) ball indenters.
HERV-K (HML-2) Envelope Protein Induces Mitochondrial Depolarization and Neurotoxicity via Endolysosome Iron Dyshomeostasis
Authors: Halcrow Peter W. , Quansah Darius N.K. , Kumar Nirmal , Steiner Joseph P. , Nath Avindra , Geiger Jonathan D.
Published: February 2024

Human endogenous retroviruses (HERVs) are associated with the pathogenesis of amyotrophic lateral sclerosis (ALS); a disease characterized by motor neuron degeneration and cell death. The HERV-K subtype HML-2 envelope protein (HERV-K Env) is expressed in the brain, spinal cord, and cerebrospinal fluid of people living with ALS and through CD98 receptor-linked interactions causes neurodegeneration. HERV-K Env-induced increases in oxidative stress are implicated in the pathogenesis of ALS, and ferrous iron (Fe2+) generates reactive oxygen species (ROS). Endolysosome stores of Fe2+are central to iron trafficking and endolysosome deacidification releases Fe2+into the cytoplasm. Because HERV-K Env is an arginine-rich protein that is likely endocytosed and arginine is a pH-elevating amino acid, it is important to determine HERV-K Env effects on endolysosome pH and whether HERV-K Env-induced neurotoxicity is downstream of Fe2+released from endolysosomes. Here, we showed using SH-SY5Y human neuroblastoma cells and primary cultures of human cortical neurons (HCNs, information on age and sex was not available) that HERV-K Env (1) is endocytosed via CD98 receptors, (2) concentration dependently deacidified endolysosomes, (3) decreased endolysosome Fe2+concentrations, (4) increased cytosolic and mitochondrial Fe2+and ROS levels, (5) depolarized mitochondrial membrane potential, and (6) induced cell death, effects blocked by an antibody against the CD98 receptor and by the endolysosome iron chelator deferoxamine. Thus, HERV-K Env-induced increases in cytosolic and mitochondrial Fe2+and ROS as well as cell death appear to be mechanistically caused by HERV-K Env endocytosis, endolysosome deacidification, and endolysosome Fe2+efflux into the cytoplasm.
Immune Cell Response of the Spleen in COVID-19
Authors: Perepelitsa S. A.
Published: February 2024

Objective. To study the morphometric characteristics and splenic immune cell response in patients with COVID-19.

Material and methods. A prospective observational study included 70 patients. Of these, 45 patients admitted to the infectious diseases hospital with Coronavirus infection caused by the SARS-CoV-2 virus diagnosis were included in the COVID-19 group, and 25 patients were included in the acute respiratory viral infection (ARVI) comparison group. Spleen linear dimensions, including length, width, and thickness were assessed using ultrasound imaging, and calculations of the spleen weight and spleen weight coeﬃcient (SWC) were obtained. Additionally leukocyte count and formula, erythrocyte sedimentation rate (ESR) were estimated, and the leukocyte index (LI) and neutrophil-to-lymphocyte ratio (NLR) were calculated.

Results. Microsplenia was common in the acute period of COVID-19 with mean SWC value 1.6±0.2. In 17 (37.8%) patients the SWC varied from 1.0 to 1.5, and in 9 (20%) microsplenia was critical with SWC <1.0. Leukocyte count was lower, and ESR — higher in patients with COVID-19, compared to ARVI group (5.4±2.1×10⁹/l and 10.8±4.8×109/l, respectively P<0.00001, and ESR — 36.1±13.8 mm/h and 23.0±5.1 mm/h, respectively P=0.03). The course of COVID-19 was characterized by a slight decrease in LI — from 0.29±0.02 to 0.22±0.01 (P=0.19), and significant increase in NLR from 3.7±0.1 to 4.3±0.12 (P=0.002). Opposite trends were documented in patients with ARVI. On Day 5 since initiation of treatment LI was significantly lower in the COVID-19 vs ARVI group (0.22 [0.16; 0.39] vs. 0.48 [0.29; 0.93], P=0.003), and NLR was significantly higher (4.3 [2.5; 6.1] vs. 2.1 [0.9; 2.9], P=0.002).

Conclusion. The course of coronavirus infection caused by the SARS-CoV-2 virus is characterized by significant immunological shifts. Microsplenia verified by ultrasonography stays as one of the pathognomonic signs. This phenomenon is explained by rapid «depletion» of the spleen as a secondary immune organ, and is associated with a high risk of developing acute immune deficiency.
Linking Immunological Parameters and Recovery of Patient’s Motor and Cognitive Functions In The Acute Period of Ischemic Stroke
Authors: Tynterova A. M. , Shusharina N. N. , Golubev A. M. , Moiseeva E. M. , Litvinova L. S.
Published: February 2024

Objective. To evaluate the relationship between immunological parameters and functional outcome in patients with varying severity of ischemic stroke based on statistical methodology.

Materials and methods. The prospective study included 78 patients diagnosed with ischemic stroke, who were distributed into two groups: group 1 — 38 mild stroke patients, NIHSS score < 5, group 2 — 40 moderate stroke patients, NIHSS score 5–15. Signs of stroke severity, degree of disability, cognitive decline, and activities of daily living were chosen as criteria to estimate the functional outcome by calculating the difference between the NIHSS, mRS, MoCA, and BI scales at the time of admission and on Day 12 of hospital stay. Lab tests included assessment of plasma concentrations of CXC and CC subfamilies of cytokines, interleukins and TNF-a on Day 2 of hospital stay. Machine learning algorithms, the Python programming language, the Pandas and SciPy libraries, and discriminant analysis were used for statistical processing.

Results. The following parameters were found as significant: concentrations of IL-1b and MPIF-1/CCL23 for — for group 1, and concentrations of IL-16, MPIF-1/CCL23, Eotaxin-2/CCL24, Gro-a/CXCL1 and IL-8/CXCL8 for group 2 patients. Positive correlation was established between NIHSS dynamics and concentrations of TNF-a (R=0.227, P=0.001), MPIF-1/CCL23 (R=0.380, P=0.00061) and Gro-a/CXCL1 (R=0.211, P=0.00001), and between changes in mRS and concentrations of MPIF-1/CCL23 (R=0.277, P=0.00006), Gro-a/CXCL1 (R=0.211, P=0.0075) and IL-16 (R=0, 211, P=0.00001). There was a significant negative correlation between cognitive dysfunction and concentrations of Eotaxin-2/CCL24 (R=–0.378, P=0.00075), Gro-a/CXCL1 (R=–0.313, P=0.0035), and IP-10/CXCL1 (R=–0.214, P=0.00023), and between limited activities of daily living (IB) and concentrations of MPIF-1/CCL23 (R=–0.345, P=0.0024) and Gro-a/CXCL1 (R=–0.210, P=0.00001).

Conclusion. Chemokines form the CC family — MPIF-1/CCL23 and Eotaxin-2/CCL24, and the CXC-Gro-a/CXCL1 and IL-16 clusters are the principal cytokines associated with the dynamics of patient’s motor and cognitive functions recovery in the acute period of ischemic stroke. Although obtained results demonstrate negative effect of increased MPIF-1/CCL23, Gro-a/CXCL1, IL-16 and Eotaxin-2/CCL24 concentrations on the improvement of motor and cognitive impairments, further studies are needed to verify the CXC and CC subfamilies chemokines as prognostic markers of patient’s functional outcome in the acute period of ischemic stroke.
New Experimental Results on the Flow Regimes in Closed Channel Flows of Wood Fibre Suspensions
Authors:   Department of Physics, P.O. Box 35 (YFL), FI-40014 University of Jyväskylä, Finland, Jäsberg Ari ,   VTT, P.O. Box 1603, FI-40101 Jyväskylä, Finland, Kataja Markku ,   Department of Physics, P.O. Box 35 (YFL), FI-40014 University of Jyväskylä, Finland
Published: February 2024

We consider here the behaviour of wood ﬁbre suspension with ﬁbre concentration above that of sedimentation in a pressure driven ﬂow in a straight pipe with smooth walls. The ﬂow behaviour can be roughly divided in two main regimes: the plug ﬂow regime that occurs at low ﬂow rates and the drag reduction regime that occurs at high ﬂow rates. We utilized new experimental methods in order to gain more detailed understanding on the ﬂow behaviour of wood ﬁbre suspensions, and especially on the relevant physical phenomena inducing such behaviour. In addition to carrying out conventional loss experiment, the velocity proﬁles across the pipe were measured using pulsed ultrasound velocimetry (PUDV) techniques, and the thickness of the lubrication layer in fully developed ﬂow was measured using a laseroptical device. Based on our direct measurements, we were able to identify ﬁve different ﬂow regimes in suspension ﬂows. In addition, we reﬁned the qualitative picture of these ﬂows in relation to the forming of ﬁbre plug and to the physical phenomena taking place in transition from one ﬂow regime to another one.
Prototipo de aplicativo Android para el dimensionamiento electromecánico de cadenas de aisladores de vidrio bajo norma IEC-60071 Y IEC-60815 (2008)
Authors: Millan Montalvo Fabrizio Armando , Huamani Cornejo Jose Andres , Izquierdo Perez Jose Raul , Rosales Inga Christian Edward , Salazar Tello Karla Edita
Published: February 2024

In this study, a new Android application was developed to help users accurately determine the dimensioning of a string insulator through the analysis of the evaluation of two methods based on IEC-60071 and IEC-60815 (2008) standards. The first method uses equations from IEC-60815-2 (2008), while the second method considers parameters such as relative air density and pressure. To ensure reliability, both methods are evaluated: the first through the creepage factor to determine if the chosen profile is suitable, and the second through lightning and switching critical flashover voltages to avoid insulator flashover. Tests were carried out using data from real projects, and those results were compared with the results obtained from the application. The number of string insulators obtained from the tests was exactly the same as the number obtained from the application, except in two cases. Of the three evaluations, all cases complied satisfactorily with at least two tests.
Comportamiento organizacional y metodologías ágiles en una entidad aseguradora, sede San Isidro (Lima- Perú), 2022
Authors: Reyes Freitas Rodrigo , Huachaca Urbina Antonio Roberto
Published: February 2024

Agile methodologies make possible and encourage change in companies, as today, companies that resist change are doomed to fail. Therefore, the objective of this work is to demonstrate that there is a direct and significant relationship between organizational behavior and agile methodologies in an insurance company located in San Isidro. The research was correlational, with a quantitative approach and a non-experimental design. The convenience sample consisted of 30 employees, who were asked to complete a Likert-type questionnaire with a scale from 1 to 5. It was possible to conclude that a direct and significant relationship exists between organizational behavior and agile methodologies, as well as a strong and positive correlation between them, with a Spearman’s coefficient of 0.8650.
Aprovechamiento de la semilla de palta Hass (Persea americana) por pirólisis rápida y su evaluación en el rendimiento de obtención de bio-oil y biochar
Authors: Flores Izquierdo Manuel Antonio
Published: February 2024

En este estudio se investiga el uso de residuos de la agroindustria de exportación en el Perú, específicamente de la semilla de palta Hass, en el proceso de pirólisis para obtener bio-oil y biochar. El proceso se lleva a cabo en un reactor tubular al vacío a una velocidad de calentamiento de 8.4°C/min, con un tamaño de partícula inferior a 2 mm, a temperaturas de 300°C, 400°C y 500°C por un periodo de tres horas y tres réplicas. Los hallazgos sugieren que la temperatura influye significativamente en el rendimiento del bio-oil y del biochar. Los resultados muestran que el mayor rendimiento de bio-oil (46.47%) se obtiene a 500°C, mientras que el mayor rendimiento de biochar (45.33%) se obtiene a 300°C. Además, se ha demostrado con un valor de significación estadística (p < 0.05) que existe una variación notable en el rendimiento entre el bio-oil y el biochar, y también entre los rendimientos a diferentes temperaturas.
Who should Issue a Permit for the Memorial? Administrative Law as a Platform for the Conflict over the Construction of the Monument to the Victims of the Smoleńsk Tragedy in Warsaw
Authors: Eckhardt Piotr
Published: February 2024

Circles associated with the ruling Law and Justice party decided to build a monument to the victims of the crash of a Polish government airplane in Smoleńsk on April 10, 2010 in Piłsudski Square in Warsaw. However, the authorities of that city, associated with the political opposition, were not positive about the project. Government bodies instrumentally used (and even abused) existing institutions of administrative law to build the monument despite the opposition of the local self-government. First, control over Piłsudski Square was taken away from the city authorities. Then the square was declared a closed area of military importance so that the city authorities could not make it difficult to obtain permission to build the monument. Finally, the Polish parliament created special legislation to make it more difficult to remove the monument in the future.
Words or Word Forms in the Particle Role: The Case of Slovene
Authors: Žele Andreja
Published: February 2024

This paper presents particles and other words used as particles in Slovene. It is particularly focused on the conversion of other parts of speech into particles. The functional structuralist approach is adopted, which classifies parts of speech in terms of their syntactic-semantic role in the clause. The particle as a dynamic function word as well as a clause modifier is presented from both a theoretical and practical standpoint and thus the paper concerns both linguistic observations on particles and the practical, i.e. lexicographic, treatment of particles in Slovene texts. With true particles, the text often alternates between a stressed modal role expressing the speaker's evaluation of what is being commu- nicated, and a related connective role.Various situational contexts in communication cause syntactic-semantic inversions between the ex- pressive and connective roles to be very common and ordinary, thereby functionally likening particles to conjunctions. A particle as a nonmember of sentence has neither substantive nor grammatical in- dependent meaning and is therefore often in a conversion relationship with other parts of speech. In Slovene, it is thus confirmed that at least 25% of all particles especially due to their nonindependent generalized meaning, can be in a conversion relationship with other parts of speech. More frequent conversion relationships include interjection → particle, adverb → particle, conjunction → particle, noun → particle, verb → particle.
The Process of English Internationalization in the Ukrainian Educational Paradigm
Authors: Leleka Tetiana , Ivanenko Nadiia , Demeshko Inna , Kapitan Tetiana , Demchenko Inha
Published: February 2024

The research is devoted to the study of the problem of English loanword adaptation in the Ukrainian youth slang as a result of innovative processes in the educational system caused by the flow of language globalization. The globalization of the English language as a result of the information revolution and of all human activity is an unprecedented phenomenon in the world language system that is altering widely held beliefs about literacy and foreign languages. The main hypothesis of the study is an increase in the number of borrowed words in the speech of the Ukrainian youth. The paper attempts to analyze the trends in the use of the loanwords that have Ukrainian one-word equivalents over 5 years, from 2016 to 2021. To obtain data on the use of loanwords, respondents aged 15–17 (school pupils), 18–20 (university students), and 21–23 (university graduates) have been interviewed. According to the problems mentioned, the article aims to describe the use of English loanwords in the Ukrainian language caused by language globalization. The study intends to explore whether Ukrainian speakers prefer to use English loanwords instead of the Ukrainian equivalents that are connected with the role of English in the educational system and whether gender is a significant factor in the use and further assimilation of English loanwords.
Temporal analysis of therapeutic approaches to osteogenesis imperfecta in the context of pediatric orthopedics - an update
Authors: Gabriella de Oliveira Bianca , Luiza Medina Giovanna , Dantas Araújo Armando , Antônio Biazussi Alberto , Dalferth de Oliveira Júlio César , Aires Marques Melissa Alves
Published: February 2024

Osteogenesis Imperfecta (OI), popularly known as brittle bone disease, is characterized by bone fragility and deformities, as well as fractures caused by minor trauma. Prevention to reduce the number of fractures, treatment of fractures and surgical correction of deformities are a challenge for orthopaedic surgeons in their therapeutic management. The aim of this study is to analyze the therapeutic approaches to osteogenesis imperfecta in Brazil from 2013 to 2022. This is a retrospective qualitative and quantitative clinical investigation, in which the information was obtained from the Ministry of Health databases (TABNET), made available by the Department of Informatics of the Unified Health System (DATASUS), using the health science descriptors: "osteogenesis imperfecta", "pediatrics" and "bone fractures". It can be seen that between 2013 and 2022, 9,461 treatments for osteogenesis imperfecta were recorded in Brazil, so even though it is considered a rare pathology, it has a significant number of cases. Thus, the long-term aim of therapeutic interventions is for these children to live independently and develop the life skills that will enable them to coordinate their own care
Archaeology of the lower South of Bahia: engenho rio de contas, Itacaré, Bahia, Brazil
Authors: Alberto Santos Costa Carlos , Comerlato Fabiana , da Silva Cunha Cinthia
Published: February 2024

The Engenho Rio de Contas is a sugar mill that operated along the river Rio de Contas in Bahia, between the 18th and early 20th centuries. In 2007, the construction of highway BA-001 (Camamu and Itacaré) gave the opportunity to collect and analyze the historical and archaeological data of this facility. This site was analyzed from the notion of “sugar mill” elaborated for the understanding of the productive system and distant from the traditional conceptions minted in the official historiography. Thus, it was interpreted as a large production structure, adapted to the local reality and immersed in a network of production and commerce, with diffuse territorial control.
The walking dead: Identity, variability, and cultural interactions of funerary behaviors between Crete and mainland Greece during the Early Iron Age (11th to 8th BC)
Authors: Diogo de Souza Camila
Published: February 2024

This paper aims to examine funerary contexts of sites in mainland Greece and compare them with sites on the island of Crete in Ancient Mediterranean during the Early Iron Age, in the period of circa the 11th until the 8th centuries BC. From an integrative approach to the analysis and interpretation of material culture from funerary contexts allow us to understand aspects of the space of the dead, aspects of mortuary practices and their role in the configuration of the historical context of the rise and formation of the polis, especially during the 8th century BC. The comparative analyses also provide a better understanding about contact and interactions in the Mediterranean. This requires us to analyze and consider on the different nature of material culture from funerary contexts, such as types of treatment and deposition/disposal/placement of the body of the dead, the construction of funerary architecture, grave goods, and the agency of the space of the dead in the construction of the funerary topography (funerary landscape). Cultural interactions are material expressions resulting from the exchange of ideas, know-how, technique and technology, beliefs, customs, and behaviors, both from objects and from the movement of people. They constitute a prospective field to address mortuary archaeological data as an active part of death and of the social process of dying. Funerary behaviors assign meanings, build memories and identities to biological death. They bring life to the transition of an active person in the “world of the living” into a passive “material thing” in the “world of the dead”. Thus, the dead, become the “walking dead” and “come to life”. Cultural interactions during the Early Iron Age constitute a fundamental element in the configuration of a new historical structure, the polis, which characterizes the Greek world as a unit – not homogeneous but consisting of heterogeneous and idiosyncratic aspects. Mortuary practices integrate this world of simultaneously standardized and peculiar actions and have crucial roles in the hellenic identity and in the identity particularities of its polis in Greek mainland and Crete.
Ratio the addition of soursop fruit extracts to several components of the quality sweet corn milk yogurt
Authors: Saputrayadi Adi , MP Asmawati , Sulastri Yeni , M Firman
Published: February 2024

Corn milk yogurt can be made so that the resulting types of fermented milk products in different forms. One ingredient that can be added is soursop fruit extract to increase levels of vitamin C because soursop fruit has a high Vitamin C content of 20.00 mg. This study aims to determine the effect of the ratio of the addition of soursop fruit extracts to several components of the quality of sweet corn milk yogurt. The research method used was an experimental method. This study was designed using a Completely Randomized Design (CRD) with various treatments as follows: T1 = soursop fruit extract 0 ml + 250ml sweet corn milk, T2 = soursop fruit extract 12.5ml + sweet corn milk 237.5ml, T3 = 25ml soursop fruit extract + 225ml sweet corn milk, T4 = 37.5ml soursop fruit extract + 212.5ml sweet corn milk, T5 = 50ml soursop fruit extract + sweet corn milk 200ml. The research data were processed by analysis of diversity (Analysis of Variance) at 5% significance level and if there were treatments that had a significant effect, it was continued with BNJ test at 5% level. The results showed that the ratio of the addition of fruit extracts soursop has a significant effect on all parameters of chemical properties, namely lactic acid, pH value, vitamin C content and organoleptic properties, namely color, smell, taste and texture. The higher the ratio of the addition of soursop fruit extract, the higher levels of lactic acid and vitamin C levels while the pH value is lower. The higher the ratio of the addition of soursop fruit extracts, the color score of organoleptic values ​​with the criteria of cream, the taste with the criteria of very like and the smell with the criteria of very like while the thickness decreases with the criteria being rather thick. The best addition ratio of soursop fruit extract was obtained in T5 treatment, which was a mixture of 50 ml of soursop fruit extract with 200 ml Sweet corn.
The Association of Childhood Parental Connection With Adult Flourishing and Depressive Symptoms
Authors: Whitaker Robert C. , Dearth-Wesley Tracy , Herman Allison N.
Published: February 2024

OBJECTIVES

To determine whether a common measure of childhood emotional neglect, scored instead as a continuous measure of increasing parental connection, is associated with adult flourishing and depressive symptoms, and to compare the magnitude of these 2 associations.

METHODS

We pooled cross-sectional survey data from the Midlife in the United States study, collected from 2 national cohorts (2004–2006 and 2011–2014) of English-speaking, US adults, aged 25 to 74 years. Using the 5-item emotional neglect subscale of the Childhood Trauma Questionnaire, a score of increasing childhood parental connection was created by not reverse-scoring responses. The adult outcomes were standardized scores of flourishing, from Ryff’s Psychological Well-Being Scale, and depressive symptoms, from the Center for Epidemiologic Studies Depression Scale.

RESULTS

Data were available for 2079 of 2118 participants (98.2%). The mean (SD) age was 53.1 (12.6) years and 54.6% were female. After adjusting for covariates (age, gender, race and ethnicity, marital status, chronic disease, socioeconomic disadvantage), the adult flourishing score was 0.74 (95% confidence interval 0.63–0.86) SD units higher in those in the highest quartile of childhood parental connection compared with the lowest, whereas the depressive symptoms score was lower by a similar magnitude (−0.65 [95% confidence interval −0.77 to −0.54] SD units).

CONCLUSIONS

When emotional neglect is reframed as parental connection, it has associations with adult flourishing and depressive symptoms that are of similar magnitude but opposite direction. Clinicians and researchers should consider the more positive and aspirational frame of parental connection and its potential contribution to life course flourishing.
Climate Change and Children’s Health: Building a Healthy Future for Every Child
Authors: Ahdoot Samantha , Baum Carl R. , Cataletto Mary Bono , Hogan Patrick , Wu Christina B. , Bernstein Aaron ,   COUNCIL ON ENVIRONMENTAL HEALTH AND CLIMATE CHANGE, Bole Aparna , Balk Sophie J. , Byron Lori G. , Huerta-Montañez Gredia Maria , Landrigan Philip J. , Marcus Steven M. , Nerlinger Abby L. , Patel Lisa H. , Philipsborn Rebecca , Woolf Alan D. , Zajac Lauren , Gray Kimberly A. , Briskin Jeanne , DeNicola Nathaniel G. , Karwowski Matt , Ward Mary H. , Spire Paul ,   COUNCIL ON CHILDREN AND DISASTERS, Krug Steven E. , Chung Sarita , Baum Carl R. , Dahl-Grove Deanna L. , Davies H. Dele , Dziuban Eric J. , Gardner Aaron H. , Griese Stephanie E. , Needle Scott M. , Schonfeld David J. , Simpson Joelle N. , Smiley Stephanie ,   SECTION ON PEDIATRIC PULMONOLOGY AND SLEEP MEDICINE, Kravitz Richard M. , Bhatia Rajeev , Guilbert Theresa W. , Gustafson Brooke , Kancherla Binal , Kopp Benjamin , Millard Susan L. , Nevel Rebekah J. , Sokolow Andrew G. , Van Hook Kristin , Laskosz Laura N. ,   SECTION ON MINORITY HEALTH, EQUITY, AND INCLUSION, Garris Nia Heard , Brown Kimberly , Chomilo Nathan , Jones Nathaniel , Rodriguez Patricia , Walker Valencia , Onyema-Melton Ngozi
Published: February 2024

The warming of our planet matters to every child. Driven by fossil fuel-generated greenhouse gas emissions, climate conditions stable since the founding of modern pediatrics in the mid-nineteenth century have shifted, and old certainties are falling away. Children’s physical and mental health are threatened by climate change through its effects on temperature, precipitation, and extreme weather; ecological disruption; and community disruption. These impacts expose and amplify existing inequities and create unprecedented intergenerational injustice. Fossil fuel extraction and combustion cause harm today and reach centuries into the future, jeopardizing the health, safety, and prosperity of today’s children and future generations. Appreciating the unique vulnerability of their patients, pediatricians have become leading health advocates for climate actions necessary to protect all living and future children. Policies that reduce reliance on fossil fuels and promote cleaner air, facilitate walking and bicycling, encourage more sustainable diets, increase access to nature, and develop more connected communities lead to immediate gains in child health and equity, and build a foundation for generations of children to thrive.
High rates of intestinal colonization with carbapenemase producing Enterobacteriaceae in hematopoietic stem cell transplant recipients
Authors: Ayari Ikram , Chebbi Yosra , Raddaoui Anis , Belloumi Dorra , Frigui Siwar , Werhni Rim , Ben Othmen Tarek , Abedejlil Nour , Achour Wafa
Published: February 2024

Carbapenem resistant Enterobacteriaceae (CRE) are major human pathogens because, these cause high number of difficult-to-treat infections. Allogeneic hematopoietic stem cell transplant (AHSCT) recipients are highly exposed to these type of bacteria. The aim of our study was to investigate prevalence of CRE colonization in AHSCT patients and to determine genes encoding carbapenem resistance. A retrospective study conducted between January 2015 and December 2019, involved 55 patients colonized with CRE strains. We determined the rate of antibiotic resistance according to European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the carbapenem resistance genes by PCR assays for genes encoding most frequent β-lactamases namely, blaGES, blaKPC, blaIMI, blaNDM, blaVIM, blaIMP and blaOXA-48. Eighty-one episodes of CRE colonization were recorded in 55 patients, mainly suffering from acute leukaemia (30%) and aplastic anemia (26%). History of hospitalization was noted in 80 episodes. Prior antibiotic treatment, severe neutropenia and corticosteroid therapy were respectively found in 94%, 76% and 58% of cases. Among the 55 patients, six patients (11%) developed a CRE infection. The CRE responsible for colonization were carbapenemase producers in 90% of cases. They belonged mostly to Klebsiella pneumoniae (61/81) and Escherichia coli species (10/81). Antibiotic resistance rates were 100% for ertapenem, 53% for imipenem, 42% for amikacin, 88% for ciprofloxacin and 27% for fosfomycin. Molecular study showed that blaOXA-48 gene was the most frequent (60.5%), followed by blaNDM (58%). Thirty-five (43%) strains were co-producers of carbapenemases. In our study, we report a high rate of CRE intestinal colonization in AHSCT recipients of our center.
A Life in the Day of Alan Davidson
Authors: Saberi Helen
Published: February 2024

Memoir recounting a typical day in the life of Alan Davidson the diplomat and pioneering food historian during the time when the author was assisting him in his work on the Oxford Companion to Food.
Tasting a Neighbourhood
Authors: Beck Peter
Published: February 2024

The author looks at the changing food landscape of the Lower East Side neighbourhood of NYC, one which has always been known for its food. Includes conversations with owners of one of the last remaining old-time family run stores, Russ & Daughters.
Susan P. Mattern: The Prince of Medicine: Galen in the Roman Empire
Authors: Wilkins John
Published: February 2024

Susan P. Mattern: The Prince of Medicine: Galen in the Roman Empire: Oxford University Press, 2012: 368 pp., hardback, £20.
Ben Downing: Queen Bee of Tuscany: The Redoubtable Janet Ross
Authors: Jaine Tom
Published: February 2024

Ben Downing: Queen Bee of Tuscany: The Redoubtable Janet Ross: Farrar, Strauss and Giroux, 2013: 340 pp., hardback, £22.85.
Ben Highmore: The Great Indoors. At Home in the Modern British House
Authors: Jaine Tom
Published: February 2024

Ben Highmore: The Great Indoors. At Home in the Modern British House: Profile, 2013: 292 pp., hardback, £15.99.
DEVELOPMENT OF APPLIED ONTOLOGY FOR THE ANALYSIS OF DIGITAL CRIMINAL CRIME
Authors: Vlasenko L. O. , Lutska N. M , Zaiets N. A. , Savchenko T. V. , Rudenskiy A. A.
Published: February 2024

Context. A feature of the modern digital world is that crime is often committed thanks to the latest computer technologies, and the work of law enforcement agencies faces a number of complex challenges in the digital environment. The development of information technology and Internet communications creates new opportunities for criminals who use digital traces and evidence to commit crimes, which complicates the process of identifying and tracking them.

Objective. Development of an applied ontology for a system for analyzing a digital criminal offense, which will effectively analyze, process and interpret a large amount of digital data. It will help to cope with the complex task of processing digital data, and will also help automate the process of discovering new knowledge.

Methods. To build an ontological model as a means of reflecting knowledge about digital crime, information was collected on existing international and domestic classifications. The needs and requirements that must be satisfied by the developed ontology were also analyzed. The creation of an ontological model that reflects the basic concepts, relationships in the field of digital criminal offense was carried out in accordance with a recognized ontological analysis of a specialized subject area.

Results. An applied ontology contains the definition of entities, properties, classes, subclasses, etc., as well as the creation of semantic relationships between them. At the center of the semantics is the Digital Crime class, the problem area of which is complemented by the interrelated classes Intruder, Digital evidence, Types of Crime, and Criminal liability. Such characteristics as motive, type of crime, method of commission, classification signs of digital traces and types of crime, as well as other individual information were assigned to the attributes of the corresponding classes. An ontological model was implemented in OWL using the Protégé software tool. A feature of the implementation of the applied ontology was the creation of SWRL rules for automatically filling in additional links between a class instance. Manual and automatic verification of the ontology showed the integrity, consistency, a high degree of correctness and adequacy of the model. The bugs found were usually related to technical aspects and semantic inconsistencies, which were corrected during further development iterations.

Conclusions. The research confirmed the effectiveness of the developed applied ontology for the analysis of digital criminality, providing more accurate and faster results compared to traditional approaches.
THE FREQUENCY METHOD FOR OPTIMAL IDENTIFICATION OF CLOSE-LOOP SYSTEM ELEMENTS
Authors: Osadchyi S. І. , Zozulya V. A. , Kalich V. M. , Timoshenko A. S.
Published: February 2024

Context. The article is devoted to overcoming the contradictions between the assumptions adopted in known methods of closedloop control system identification and the design and conditions of its operation. The article presents a new method of identifying the transfer functions matrix of a two-level closed-loop control system element, which functions under the conditions of multidimensional stationary centered random influences.

Objective. The purpose of the study, the results of which are presented in this paper, is to extend the indirect identification method to the case of estimating one of the two-level closed-loop control system elements’ dynamics model based on passive experiment data.

Method. To solve the optimal identification problem, a variational method for minimizing the quality functional on the class of fractional-rational transfer function matrices was used.

Results. As a result of the research, the identification problem formulation was formalized, the rules for obtaining experimental information about the input and output signals were determined, the rules for identifying the transfer functions matrix of a two-level closed-loop control system element, which minimizes the sum of the variances of identification errors in the frequency domain, and the verification of these rules was carried out.

Conclusions. Justified rules allow to correctly determine transfer functions matrices of the closed-loop systems selected element when fulfilling the defined list of conditions. The closed-loop systems control paths signals analysis proves the possibility of the effect of changing these signals statistical means, even under conditions of only centered stationary input influences actions on the system. Based on this, the further development of research can be aimed at overcoming such effects.
The turbulence models review for aerodynamic, thermal and structural problems in jet engine turbines
Authors:   Perm National Research Politechnic University, Gladkikh Pavel , Trusov Peter ,   Perm National Research Politechnic University
Published: February 2024

In the processes of their processing to obtain finished products, the internal structure and the properties of various scale levels of the material that depend on it change significantly, the prediction of which using empirical methods is extremely costly. For this reason, the development of processing technologies is unthinkable without mathematical models, the central element of which is constitutive relations. A promising approach for constructing the latter is the physical approach, which makes it possible to describe the evolution of the internal structure at various scale levels. As a rule, such models of materials are multilevel and represent a whole class of constitutive models. Of particular interest are elastoplastic models, since they allow calculations with sufficiently large time steps. Most models of this type are based on the Taylor - Bishop - Hill model. Models of this type have a drawback: uncertainty in the choice of a set of active slip systems. This uncertainty is due to the fact that the dislocation shear rates along slip systems are determined from a system of equations, the dimension of which may exceed the dimension of the space of independent variables being sought. In this paper, we study the influence of a random choice of sets of active slip systems in elastoplastic models of the Taylor - Bishop - Hill type on the results of mod-eling the elastoplastic deformation of polycrystals with a face-centered cubic lat-tice. The deviation in the simulation results was considered for a random choice of sets of active slip systems. For this purpose, special metrics were introduced to show the effect of uncertainty on the macrolevel stress tensor and misorientation angles between crystallites. It is shown that with increasing strains, a random choice of sets of active slip systems leads to an almost monotonous increase in differences in the calculation of the macrolevel stress tensor and misorientation angles between grains. This fact means that the problem of uncertainty in the choice of active slip systems inherent in these models affects the simulation re-sults. The indicated discrepancy between the simulation results evidences the need to develop an algorithm to eliminate the noted uncertainty, which is the sub-ject of the forthcoming publication of the authors.
Prototype of the request in the service queue
Authors:   Saint Petersburg University of the Ministry of the Interior of Russia, Bolshakova Lyudmila , Sibarov Konstantin ,   Saint Petersburg University of the Ministry of the Interior of Russia, Yakovleva Natalia ,   Saint Petersburg University of the Ministry of the Interior of Russia
Published: February 2024

The development of a visual prototype of an application in a single queue for service is given. The pre-image connects the accounting for the growth of losses due to the duration of waiting with such sides of the importance of the application as urgency and priority. Varieties of change of urgency in time are discussed. The possibility of interpreting service as a lasting good is considered. On this basis, it is proposed to use relative losses as the main measure for determining the place of an application in the queue - the ratio of losses due to waiting to the duration of service. The example shows that the order in which service requests arrive depends on the time when the service facility starts accessing the queue and on the ratio of the service durations of individual requests. For the case of returning the service facility to the request after a forced interruption, the possibility of rivalry with it by other requests in the queue that have not yet arrived for servicing is considered. The possibility of working with the queue when servicing in small parts with a change in serviced requests is shown. For this type of work, expressions for step-by-step calculations are given. Calculations are made for two complicated cases of servicing a queue of five requests with a contradictory combination of the initial data of requests. A diagram of the switching of service facilities between requests is given. Taking into account the four sides of the description of the request in the queue at once provides the prototype with greater flexibility than most widely used queuing disciplines. The proposed prototype can be taken as a basis for building multi-parameter models of applications and algorithms for automatic control of the queue of applications for social, economic and computational applications.
Study of Security Mechanisms Cloud Services
Authors:   Volgograd State University, Golovacheva Natalia , Romanov Maxim ,   Volgograd State University
Published: February 2024

The article analyzes the protection mechanisms of cloud services. Criteria for adequate evaluation of these mechanisms are identified. In the framework of experimental research, the best mechanism of cloud service protection is identified, taking into account the requirements and needs of the user. In the modern information society, everyone is faced with the problem of securely storing various passwords, logins and other data. Someone wrote them down in a notebook or just on a piece of paper that was glued to the computer from which they authenticated. All this is long in the past. Any data leak will cause moral and material harm to both an ordinary person and a large company. Today, cloud computing is used for this as the main method of storing data at work or at home. The leaders in cloud technologies are the following Internet services: Dropbox, OneDrive, Google Drive, iCloud, Yandex.Disk, Cloud Mail.Ru, MegaDisk, Mega, BOX, pCloud, Files.fm, WDfiles.ru, wdho.ru, Anonfile.com, My-Files.Ru. Not only must cloud service providers protect their customers, network infrastructure, applications and platforms, but the user himself must ensure the security of his data and applications using strong passwords and authentication measures.
Cilia and Nodal Flow in Asymmetry: An Engineering Perspective
Authors: Messmore Madisyn , Kassab Alain J. , Prather Ray O. , Arceo David A. Castillo , DeCampli William
Published: February 2024

Over the past several years, cilia in the primitive node have become recognized more and more for their contribution to development, and more specifically, for their role in axis determination. Although many of the mechanisms behind their influence remain undocumented, it is known that their presence and motion in the primitive node of developing embryos is the determinant of the left-right axis. Studies on cilial mechanics and nodal fluid dynamics have provided clues as to how this asymmetry mechanism works, and more importantly, have shown that direct manipulation of the flow field in the node can directly influence physiology. Although relatively uncommon, cilial disorders have been shown to have a variety of impacts on individuals from chronic respiratory infections to infertility, as well as situs inversus which is linked to congenital heart disease. After first providing background information pertinent to understanding nodal flow and information on why this discussion is important, this paper aims to give a review of the history of nodal cilia investigations, an overview of cilia mechanics and nodal flow dynamics, as well as a review of research studies current and past that sought to understand the mechanisms behind nodal cilia's involvement in symmetry-breaking pathways through a biomedical engineering perspective. This discussion has the additional intention to compile interdisciplinary knowledge on asymmetry and development such that it may encourage more collaborative efforts between the sciences on this topic, as well as provide insight on potential paths forward in the field.