bluuebunny/crossref_metadata_2025 huggingface dataset:
Looking to the past to shape Parliament’s future Yunus Carrim says hamba kahle, after 30 years in the House
Authors: Levy Moira ,   Institute for African Alternatives (IFAA)
Published: July 2024

On the eve of his retirement after 30 years as a Member of Parliament, Yunus Carrim shares a timely reminder of South African democracy’s “glorious” days. In an interview with MOIRA LEVY he reminisced about the 1994 Parliament, which he described as “an organic reflection of what this country is capable of”. A long-standing veteran of student, civic, community and political struggles since the ‘70s and in what became the Mass Democratic Movement of the ‘80s and early ‘90s, Yunus Carrim says the political culture of that time was carried over into the country’s first democratic Parliament and made manifest in the ANC’s legacy of peaceful negotiations. He recalls a moment during his first term. Leaving his office at about 2am and finding that the exit gate to the parking area in the basement was closed, he had to detour past the Old Assembly chamber. As he got nearer to it, he could hear a murmur of voices and clinking of cups and cutlery.
Special issue on 30 YEARS OF DEMOCRACY
Authors: Nicol Martin ,   Institute for African Alternatives (IFAA)
Published: July 2024

Download full issue.
The Egyptian collection of the Municipal Museum « Giuseppe Barone » in Baranello (CB, Molise region Italy)
Authors: Corona Marco
Published: July 2024

The Egyptian artefacts of the Barone collection, in Baranello, present a certain variety in the typology of documents: specifically two canopic jars, three ushebtis in faïence, three amulets of the same material and a scarab in steatite, three bronze statuettes of divinities, two necklaces and a bracelet along with a group of thirteen small stone containers, some of which can be traced back to the land of the Nile because of the shape or because they are made of alabaster. Most of the materials refer to an Egyptian context of the Late Period, that is between the 7th and 4th centuries B.C.; the other objects are Roman reworkings of Egyptian originals.
There is also a certain number of fakes, bought by the collector Giuseppe Barone: they are now an integral part of the collection.
«Родила и решила…»: механика выбора предпринимательских стратегий в среде российских матерей
Authors: Симонова Ирина Александровна , Швецова Анастасия Владимировна , Кривощёкова Марина Сергеевна
Published: July 2024

Статья посвящена исследованию механики принятия решений о предпринимательских практиках и факторах выбора предпринимательских стратегий российскими женщинами, воспитывающими маленьких детей. Теоретическая рамка работы определена положениями современной социальной топологии в прочтении Дж. Ло и теорией сборки (М. Деланда, И. В. Красавин), что дает возможность рассматривать материнское предпринимательство в терминах вариативной самоорганизации, предполагающей изменения отношений, предметности, хронотопа женщины. Авторы обращаются к понятию отчуждения, поскольку общая ориентация на предпринимательскую активность и тактика реализуемых матерями проектов сопряжены с выбором в пользу полных циклов производства (контролем средств производства, реализации продукта и присвоением результатов деятельности), а практики монетизации имеют эмансипационный потенциал.
Эмпирическую основу работы составили кейсы предпринимательских историй матерей, материалы с материнских форумов и сообществ (248 релевантных высказываний матерей), глубинные интервью с матерями (n = 20, Свердловская область). Сбор данных проходил с марта 2022 г. по май 2023 г. В результате представлен репертуар ключевых предпринимательских практик по сферам, степени организованности, формам реализации; обозначены изменения в хронотопе матерей, названы ключевые мотивы предпринимательства; выделены и описаны две наиболее распространенные стратегии: мастеровая (осторожная), характеризующаяся локальностью, аритмичностью, вниманием к продукту и процедурам его производства, низкими вложениями и высокой комфортностью; менеджерская (смелая), сфокусированная на процессах организации, росте прибыли, инвестициях, расширении рынков. Выбор предпринимательской деятельности определен потребностями в балансе занятости и семьи, претензией на преодоление комплексного отчуждения. Такие факторы, как институциональные условия, поддержка домочадцев, подпитывающее окружение могут по-разному влиять на формы предпринимательства. Однако интенсивность предпринимательства является предметом выбора, а не необходимости, сознательно регулируется матерями. Описаны принципиальные для феномена материнского предпринимательства в России особенности: индивидуально-проблемный характер предпринимательских практик, их стремительность, ориентация на процесс, интуитивность, фокус на контроле всех этапов предпринимательского цикла, социальная ориентация деятельности.
Благодарность. Исследование выполнено за счет гранта Российского научного фонда № 22-28-00636 «Современные «нематеринские» практики молодых матерей: репертуар, потенциал и общественный риск», https://rscf.ru/project/22-28-00636/.
Correlation Analysis of the Intensity of Occupational Network and Resilience of Patients With Spinal Cord Injury
Authors: Son, Sung-Min Son, Sung-Min , Park, Han-Gul Park, Han-Gul ,   The Korean Society of Occupational Therapy
Published: July 2024

Objective: This study aimed to analyze the correlation between the level of occupational network and resilience among patients with spinal cord injuries. Methods: The participants of the study were 17 patients with spinal cord injury. The intensity of occupational network was analyzed using social network analysis, and the degree centrality, betweenness centrality, and eigenvector centrality were analyzed. In social network analysis, the intensity of performing the occupation was set to satisfaction. The performance of occupation survey was based on items of the classification of activities of daily living presented in the Time Use Survey of the National Institute of Statistics, allowing subjects to select activities of meaningful work. Resilience was measured using the Korean version of the Connor-Davison Resilience Scale (K-CD-RISC). Results: The results showed a positive correlation between degree centrality, eigenvector centrality, and resilience on the intensity of occupational network. These results suggest that the level of resilience increases as the level of degree centrality and eigenvector centrality increases in performing daily life activities. Conclusion: To improve the resilience of spinal cord injury patients, the intensity of degree centrality
and eigenvector centrality in performing daily living activities should be considered, and goals and plans for therapeutic intervention should be created focusing on these activities.
Analysis of the Occupational Network Structures Using Social Network Analysis Among Patients With Stroke
Authors: Son, Sung-Min Son, Sung-Min , Park, Han-Gul Park, Han-Gul ,   The Korean Society of Occupational Therapy
Published: July 2024

Purpose: This study aimed to analyze the network structures of occupation in performing daily life activities using social network analysis among stroke patients. Methods: The study subjects were 40 stroke patients. Based on the social network analysis, the network distribution, network centrality, cohesion structures were conducted to analyze performance structures of the occupational network. The performance of occupation was set as the activities which the subjects are performing in their daily life and it was measured using 45 items of the Time Use Survey of Statistics Korea. The level of satisfaction was used as the
weight of network analysis. Results: The activities with high values of degree, betweenness, and eigenvector centrality showed “personal health care” acitivey was showed as the activity with the highest values of degree, betweenness, and eigenvector centrality. Conclusion: This study’s results bear clinical significance in understanding the occupational network structures among stroke patients from a relational perspective and provide a knowledge system for the relationships and patterns of occupational performance. Furthermore, these provide insights into participating in, integrating, and enhancing occupational performance within the contexts of occupational therapy and education. Accordingly, it can serve as guidelines for establishing intervention plans and setting goals for stroke patients.
Cognitive Leisure Activity Interventions to Enhance Cognitive Function in Healthy Middle-ag ed and Older Adults Within the Community: A Systematic Review
Authors: An, Hyunseo An, Hyunseo , Park, Hae Yean Park, Hae Yean , Lee, Heysig Lee, Heysig , Nam, Sanghun Nam, Sanghun ,   The Korean Society of Occupational Therapy
Published: July 2024

Objective: This study analyzed cognitive leisure activity intervention studies in cognitively healthy middle-aged and older adult populations and establishes a foundation for application within the domestic community.
Methods: We conducted a systematic review following the PRISMA guidelines, focusing on academic journals from January 2013 to December 2023. We searched PubMed, EMBASE, Web of Science, CINAHL, and APA PsycInfo databases using the terms “elderly” or “older*”, “leisure*” or “leisure activities,” “cognitive*”, and “dementia.” We selected experimental studies with control groups and assessed their quality using the PEDro scale. Results: Six studies analyzed cognitive function interventions through leisure activities grouped into four categories: playing musical instruments, reading, board games, and jigsaw puzzles. Excluding jigsaw puzzles, the experimental group exhibited significant cognitive function improvements, including enhancements in phonological and category verbal fluency, verbal and visual working memory, executive function, inhibitory control, divided attention, visual scanning, and overall cognitive function, compared with the control group. Improvements were also observed in performance, mood, and quality of life. Conclusion: This study found that cognitive leisure activities can improve cognitive function and psychosocial domains in community populations including middle-aged and older adults. These activities can be incorporated into daily life to promote cognitive health during occupational therapy.
Survey on Job Importance and Education Needs for Occupational Therapists in Rehabilitation Hospitals
Authors: Kwon, Da Som Kwon, Da Som , Jung, Nam Hae Jung, Nam Hae ,   The Korean Society of Occupational Therapy
Published: July 2024

Objective: This study examined job importance and educational needs among occupational therapists working at rehabilitation hospitals in Busan and Gyeongnam, South Korea, and identified differences based on participants’ careers. Methods: During seven weeks, from October 23 to December 4, 2023, a survey was administered to 120 occupational therapists working at various rehabilitation hospitals in Busan and Gyeongnam. The researcher measured job importance and educational needs using a questionnaire based on Lee et al.’s (2014) study, scored using the Likert scale. Results: Counseling had the highest level of importance for each duty, and intervention planning and counseling had the highest level of education. The highest level of importance and education needs for each task was attributed to training for activities of daily living, followed by selfmanagement. There was no significant difference in the importance and education needs of each task according to career, and there was a significant difference in the importance and education needs of each task. Conclusion: This study can be used as basic data for the education and training process of occupational therapists.
España sigue invertebrada. El problema de España
Authors: Hernández Bravo de Laguna Juan
Published: July 2024

A partir del análisis de Ortega y Gasset sobre España y su crítica, la monografía se plantea el análisis de una peculiar característica siempre presente en nuestra cultura y nuestra política: la evidencia de que la propia existencia de España ha sido un problema no resuelto en cuanto realidad histórica y social, un problema que persiste en la actualidad. La monografía analiza las tesis al respecto, que constatan una intensa autocrítica y la evidencia de una incesante decadencia a partir de una corta etapa de esplendor y desarrollo. Y aborda el estudio historiográfico de esa decadencia: en España se ha puesto el sol, y la crisis de 1640 es el inicio de la larga e interminable decadencia. Los antecedentes históricos del problema español en el Antiguo Régimen prosiguen con la llegada del liberalismo y las Constituciones. Y como esos antecedentes tienen un intenso componente territorial, tal como sucede ahora mismo, la monografía estudia con detalle la historia de la organización territorial política y administrativa de España y los principios generales de la actual descentralización autonómica. Por último, la monografía aborda uno de los componentes del problema español, que ha sido un factor determinante en su virulencia y que ha llegado hasta nosotros en los años recientes de la Transición: la orientación atlántica exclusiva y la ignorancia del Mediterráneo, orientación preferente que siempre ha despertado recelos en los territorios de la Corona de Aragón, singularmente en Cataluña, por esa superioridad de Castilla.
The Effect of Moringa Leaves Extract on Sperm Motility in Male Mice Exposed to Electromagnetic Radiation of Mobile Phone
Authors: Sabrina Hasnaa Alyasi , Budisulistyo Trianggoro , Juniarto Achmad Zulfa , Sareharto Tun Paksi
Published: July 2024

Background: Electromagnetic radiation can induce an increase in oxidative stress. The presence of oxidative stress can impact the structure of the plasma membrane of sperm cells, damage the structure of Deoxyribonucleic Acid (DNA), and accelerate the process of apoptosis, ultimately leading to a decline in sperm quality. This increase in oxidative stress can be prevented by substances that serve as antioxidants. Moringa plants, particularly the leaves, contain various substances that can act as antioxidants for the body. These include flavonoids, alkaloids, saponins, tannins, and terpenoids. The antioxidant content in Moringa leaves is believed to safeguard the process of spermatogenesisAim: To determine the impact of Moringa (Moringa oleifera) leaf extract on the motility of spermatozoa in BALB/C mice subjected to exposure to electromagnetic waves.Methods: This study utilized design featuring a post-test-only control group design, dividing participants into four randomly assigned groups, namely a negative control group, a positive control group (exposure to electromagnetic waves), and 2 treatment groups (moringa leaf extract at dose of 100 mg/kg BW and 400mg/kg BW). Each group compromised 5 experimental animals, and the treatments were administered for duration of 30 days. Spermatozoa preparations were made for each group and observed under a microscope (400x). Data were analyzed by initially testing for normality using the Shapiro-Wilk test. If the data distribution was normal, the hypothesis examination involved conducting a One Way ANOVA followed by subsequent Post Hoc testing.Results: The results of the one-way ANOVA test indicated differences between groups of mice (p<0.05). The post hoc test results further demonstrated that a dose of 400 mg/kg BW was the most effective in preventing a decrease in spermatozoa motility. This effect is believed to be atttributed to the presence of vitamin C, beta carotene, beta-sitosterol, flavonoids, and polyphenols.Conclusion: There is an improvement in spermatozoa motility in BALB/C mice exposed to electromagnetic waves after the administration of Moringa leaf extract.
Correlation between Degree of Leprosy Disability and Serum IL-6 Levels in Patients with Leprosy Reactions: An Observational Study at the Donorojo Jepara Leprosy Hospital Center
Authors: Putri Syifa Nurisma , Mundhofir Farmaditya Eka Putra , Yuniati Renni , Wijayahadi Noor , Nindita Yora
Published: July 2024

Background: Leprosy is an infectious disease caused by Mycobacterium leprae bacteria which is still the focus of a global problem and causes disability in patients. The degree of disability in leprosy is assessed as mild and severe as a result of the inflammatory process. This study aims to determine the relationship between the degree of disability in leprosy and IL-6 serum levels as an inflammatory biomarker in leprosy patients. Methods: A Cross-sectional observational analytical study on leprosy patients aged 20-60 years, not pregnant, and undergoing treatment at Donorojo Jepara Hospital from March to April 2024. Serum IL-6 levels were analyzed using the ELISA method and tested for correlation with the degree of disability leprosy. Results: Statistical analysis of Spearman's correlation rank test shows a p value = 0.279 and the results of the line pattern on the Scatter dot graph are not linear. Conclusion: There is no correlation between serum IL-6 levels and the degree of disability in leprosy patients at Donorojo Jepara Hospital.Keywords: Degree of Disability in Leprosy, Leprosy, Serum IL-6
The Effect of Moringa Leaves Extracts on MDA Level in Male Mice Exposed to Electromagnetic Radiation of Mobile Phones
Authors: Amalia Nadia Ilmi , Budisulistyo Trianggoro , Wibowo Dhega Anindita , Sareharto Tun Paksi
Published: July 2024

Background: The use of cell phones causes anxiety about the effects of electromagnetic wave radiation emitted because of the production of free radicals in the body is increased by cell phone electromagnetic wave radiation. This escalation results in an elevated production of Reactive Oxygen Species (ROS), resulting in elevated Malondialdehyde (MDA) levels due to lipid peroxidation, which is toxic to the body. One way to reduce MDA levels is to introduce antioxidants into the body. Previous studies have found that Moringa leaf extract can be used as a good source of antioxidants.Objective: The aim of this research was to assess the impact of Moringa leaf extract administration on the MDA levels in BALB/C mice subjected to electromagnetic waves emitted by cell phones.Methods: This study employed an experimental study with a post-test only control group design. The research involved 23 male BALB/c mice, divided into four groups. The healthy control group received no treatment, while the negative control group was exposed to cell phone electromagnetic waves for 2 hours/day. Groups P1 and P2 received Moringa leaf extract at doses of 100 mg/kgBW and 400 mg/kgBW, respectively, in addition to being exposed to cellular phone electromagnetic waves for 2 hours/day. The treatment was administered for 30 days following a 7-dayadaptation period. On the 31st day, blood plasma samples were takenfrom all mice and examined for MDA levels. The data underwent analysis through non-parametric One-Way ANOVA and subsequent Pos Hoc LSD tests. Significance is acknowledged for p-values less than 0.05.Results: The highest MDA levels were found in the K (-) group, namely 0.43 ± 0.18 ppm, and the lowest MDA levels were observed in the P1 group, with values of 0.19 ± 0.08 ppm. A significant difference was noted between the K (-) group and the P1 group (p = 0.05), while no significant difference were observed in the other groups.Conclusion: Administering Moringa leaf extract at a dose of 100 mg/kgBW/day can reduce MDA levels in mice exposed to electromagnetic waves from cell phones.
Skin Wound Healing in Obese and Lean Male Adolescent Rats Submitted to Pre-Weaning Litter Size Manipulation
Authors: Sabol F. , Bobrov N. , Novotný M. , Vasilenko T. , Mozeš Š. , Šefčíková Z. , Molčányiová A. , Tkáčová R. , Tomori Z. , Gál Peter
Published: July 2024

We investigated whether early postnatal over-nutrition affects normal course of skin wound healing. To induce over-nutrition the litter size was adjusted on the first day after birth to four pups/nest (small litters). In parallel, as a control, normal nests of 10 pups/nest (normal litters) were used. For the wound healing experiment 30 male Sprague-Dawley rats, 15 from normal nests and 15 from small nests, were used. Two parallel full-thickness skin incisions and two full-thickness excisions were performed on the back of each rat. Samples for histological examination (excisions) and wound tensile strength measurement (incisions) were collected on days 2, 6, and 14 after surgery. Our study demonstrates that rats from the small nests had enhanced plasma levels of insulin and enhanced body weight/fat parameters. Furthermore, in small nests, rats that expressed the above-mentioned symptoms displayed slight improvement of epidermis regeneration, accelerated demarcation line formation, and increased wound tensile strength. From this point of view the small nest model used in the present experiment is helpful for exploration whether these acquired changes might be considered as a sufficient essential factor involved in the regulation of metabolic homeostasis and wound repair in juvenile obese male rats. Nevertheless, further studies need to be performed to verify the present findings also on other animal models and humans and to describe the exact underlying mechanism.
Investigations on Specific Phytochemical Characteristics of Seed Oil and Defatted Seeds of Four Oil-Producing Plants Found in Cameroon
Authors: Tangka Julius Kewir ,   Renewable Energy laboratory, FASA, University of Dschang Cameroon, Bongmo Jaff Marilyn , Etengeneng Agbor Esther ,   Renewable Energy laboratory, FASA, University of Dschang Cameroon,   Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
Published: July 2024

A study was conducted to find and create new possible sources of seed oils that might be extracted locally and utilised in Cameroon to produce biodiesel, while also valuing the defatted seeds as alternate sources of nutrients for consumption by humans and animals. Pretreatment procedures included washing and drying the seeds of Ricinodendron heudelotii (njangsa), Cucurbita maxima (pumpkin), Citrullus lanatus (watermelon), and the pulp of Raphia hookeri (raphia). A hydraulic press operating at 200 bars was then used to extract the oil from each sample. A proximate analysis was performed on both the defatted and intact seeds. While the proximate composition of the defatted cakes was examined, the extracted oils' potential for use as biodiesel was examined. The four samples' oil quality parameters were determined to be as follows: acid value (3.6 to 5.8 mgKOH/g), iodine value (19.0 to 39.0 gI2/100g), saponification value (56.1 to 280.6 mgKOH/g), and oil extracted (11.40% to 37.40%). All samples' crude protein, crude ash, and crude carbohydrate contents increased after defatting, whereas their crude lipid and crude fibre contents decreased. The highest protein content was found in defatted pumpkin seeds (41.11% DM), whilst the lowest protein content was found in defatted raffia palm pulp (7.35% DM). The findings of the oil parameter analysis indicated that all four oils have the potential to be employed as low-cost alternatives as feedstock for the production of biodiesel. The defatted seeds' results demonstrated that, with the exception of lipids, defatting concentrates macronutrients.
Pendulum at Rest Monopole Antenna (Analysis of the Complex Physical System Pendulum at Rest)
Authors: Crivoi Dumitru ,   National Institute of Inventics Iassy (retired) County, Romania, Rediu Maria ,   Gheorghe Asachi” Technical University of Iassy, Doctoral School, Romania
Published: July 2024

Background: Unexpected results (anomalies) contain essential information regarding the physical consistency of the tested system ("test body") respectively, regarding the physical consistency of the paradigm used to construct the experiment, collect data and analyze measurement results. Based on the priori information and the own information accumulated, in order to facilitate the theoretical and experimental analysis, the complex physical pendulum model composed of three subsystems was adopted, namely: the subsystem of electrical parameters of the environment S1, the subsystem of the mechanical pendulum itself S2 respectively, the disturbing subsystem of celestial bodies S3. Aims: Highlighting nongravitational perturbations of the pendulum at rest. Method(s): The representation in the form of a physical complex system by describing the processes with the help of physical laws (balance sheet equations) and experimentally. Results. A new model of the complex physical system of the pendulum at rest (antenna) and a modern gravitational-electrical paradigm (Mach-Maxwell paradigm) for experiment construction, data collection and analysis of results, respectively Conclusions: The optimal physical consistency of the new paradigm of experiment construction, data collection and analysis of measurement results allows highlighting nongravitational perturbations of the pendulum at rest.
Using Predictive Bayesian Methods to Develop A Comparative Assessment Municipal Wastewater Disposal Methods in Southeast Florida
Authors: Conboy Kelley ,   Florida Atlantic University 777 Glades Rd., Boca Raton, FL 33431, Bloetscher Frederick , Meeroff Daniel E. , Sham Chi Ho , Gallant Richard , Hart James , Muniz Albert , Shibata T. , Tuccillo Mary Ellen , Englehardt James D. ,   Florida Atlantic University 777 Glades Rd., Boca Raton, FL 33431,   Florida Atlantic University 777 Glades Rd., Boca Raton, FL 33431,   AWWA Past President 121 Washington Ave, Needam, MA 02492,   Village of Wellington 11300 Forest Hill Blvd, Wellington, FL 33414,   Calvin Giordano and Associates 580 Village Blvd., Suite 325, West Plam Beach, FL 33409,   Hazen and Sawyer, 2101 NW Corporate Blvd, Suite 301 Boca Raton, FL 33431,   University of Northern Illinois 6 Huntington Cir #10, Naperville, IL 60540,   Eastern Research Group 561 Virginia Rd, Bldg. 4 Concord, MA 01742,   University of Miami, deceased P.O. Box 248294 Coral Gables, FL 33124
Published: July 2024

Predictive Bayesian methods were used to develop a comparative assessment of the risks of six effluent disposal alternatives currently or potentially available to wastewater utilities in Southeast Florida. The alternatives are: 1) deep well injection 2) ocean outfalls following secondary treatment, 3) surface water (canal) discharges following secondary wastewater treatment, filtration and nutrient removal, 4) reclaimed water (secondary treatment plus filtration and high-level disinfection, 5) indirect potable reuse (full treatment with reverse osmosis, plus ultraviolet light and advanced oxidation) and 6) direct potable reuse using reverse osmosis, ultraviolet light and advanced oxidation. Water quality data was gathered from a series of south Florid utilities, south Florida test facilities, receiving waters and other relevant locations to south Florida wastewater effluent disposal. This paper presents the conclusions regarding relative health concerns associated with these disposal alternatives. The results indicated that health risks associated with deep wells and direct potable reuse were generally lower than those of the other alternatives.
Metafora płci jako tradycyjny stereotyp kobiety i mężczyzny w postmodernistycznym dyskursie ukraińskim (na materiale tekstów Oksany Zabużko)
Authors: Żurenko Jana
Published: July 2024

Artykuł ilustruje metafory płci w ponowoczesnym dyskursie ukraińskim na przykładzie tekstów prozatorskich Oksany Zabużko. Stereotypy w każdej kulturze to zbiór pewnych stabilnych idei narzuconych przez religie, doświadczenia historyczne i mentalne oparte na tradycjach folklorystycznych itp. oraz ogólnie przyjęte wyobrażenia o statusie społecznym na temat tego, co jest męskie, a co żeńskie. Są one obecne w każdej kulturze językowej. Badania uwarunkowane są ogólnym skupieniem się na doborze formalnych wskaźników znaków płci i sposobów ich werbalizacji, potrzebą bardziej szczegółowego i pogłębionego opisu stereotypów związanych z płcią, ukazujących historię patriarchalnego lub matriarchalnego rozwoju ludzkości oraz mają znaczenie kulturowe jako część całościowego obrazu świata, ukazując poglądy i rozumienie otaczającego świata przez jednostki – artystów. Osobowość językowa oparta na podstawie określonych przykazań społecznych, kulturowych, językowych, tworzy własną sieć skojarzeń, w której określone miejsce zajmuje metafora. Ta z kolei tworzy rdzeń wyobrażeń człowieka i rozumienia otaczającego go świata oraz jego samego w nim.
W poszukiwaniach siebie albo rekonstrukcja pamięci rodu w powieści Lisy Weedy Aleksandra. Ukraińska saga rodzinna
Authors: Puchońska Oksana
Published: July 2024

Podjęta w artykule kwestia reinterpretacji przeszłych doświadczeń jest niezwy-kle istotna w świetle współczesnych badań nad pamięcią. Autorka analizuje wpływ traumy rodu na tożsamość pokolenia millenialsów na podstawie sagi rodzinnej Lisy Weede, holenderskiej pisarki ukraińskiego pochodzenia. Powrót do tożsamości rodzinnej jest wyeksponowany w powieści Weedy zarówno na płaszczyźnie wewnętrznej (poszukiwanie przez bohaterkę treści własnego Ja), jak i ze-wnętrznej, ponieważ po rozpoczęciu wojny rosyjsko-ukraińskiej w 2014 roku uwidacznia się wzrost zainteresowania Ukrainą i ukraińskością. Interpretacja powieści Aleksandra jest przeprowadzona pod kątem trzech opcji: roli pamięci rodu w kształtowaniu się indywidualnej tożsamości, pamięci prze-strzeni oraz traumy historycznej. Pod uwagę wzięto literackie odzwierciedlenie traum kolektywizacji, Wielkiego Głodu, deportacji młodzieży z Ukrainy do hitlerowskich Niemiec na roboty przymusowe oraz współczesnej wojny w Donbasie.
Motyw powrotu do przeszłości w tomiku wierszy Oksany Zabużko Autostop
Authors: Grebeniuk Tetiana
Published: July 2024

W artykule został zbadany motyw powrotu do przeszłości zrealizowany w pierwszej części zbioru poezji Oksany Zabużko Autostop. Autorka ujawnia związek tego chwytu artystycznego z historiozoficzną koncepcją Zabużko, która została zaprezentowana w innych naukowych i literackich projektach tej autorki. Jest wyeksponowane również intertekstualne tło poetyki Zabużko, zwłaszcza aluzje do Biblii, programowych utworów Tarasa Szewczenki, poematu Jewhena Płużnyka Galileusz etc. Zgodnie z historiosoficzną koncepcją poetki dekonstruowanie sztywnej przeszłości narodu, nawet jeżeli jest dokonywane pod znakiem negacji, sprzyja rewitalizacji idei narodowej, jej rekonfiguracji ze względu na zapotrzebowania współczesne. Owe ujęcie Zabużko nawiązuje do idei Dominica LaCapry o konieczności przepracowania traum historycznych, aby uwolnić je od ograniczającego wpływu na ruch wspólnot w kierunku harmonijnej przyszłości.
RNA‐sequencing reveals differential fibroblast responses to bleomycin and pneumonectomy
Authors: Wellmerling Jack H. , Dresler Sara R. , Meridew Jeffrey A. , Choi Kyoung M. , Tschumperlin Daniel J. , Tan Qi
Published: July 2024

Pulmonary fibrosis is characterized by pathological accumulation of scar tissue in the lung parenchyma. Many of the processes that are implicated in fibrosis, including increased extracellular matrix synthesis, also occur following pneumonectomy (PNX), but PNX instead results in regenerative compensatory growth of the lung. As fibroblasts are the major cell type responsible for extracellular matrix production, we hypothesized that comparing fibroblast responses to PNX and bleomycin (BLM) would unveil key differences in the role they play during regenerative versus fibrotic lung responses. RNA‐sequencing was performed on flow‐sorted fibroblasts freshly isolated from mouse lungs 14 days after BLM, PNX, or sham controls. RNA‐sequencing analysis revealed highly similar biological processes to be involved in fibroblast responses to both BLM and PNX, including TGF‐β1 and TNF‐α. Interestingly, we observed smaller changes in gene expression after PNX than BLM at Day 14, suggesting that the fibroblast response to PNX may be muted by expression of transcripts that moderate pro‐fibrotic pathways. Itpkc, encoding inositol triphosphate kinase C, was a gene uniquely up‐regulated by PNX and not BLM. ITPKC overexpression in lung fibroblasts antagonized the pro‐fibrotic effect of TGF‐β1. RNA‐sequencing analysis has identified considerable overlap in transcriptional changes between fibroblasts following PNX and those overexpressing ITPKC.
Evaluation of Internet of Things computer network security and remote control technology
Authors: Lu Haifeng , Wu Haiwei , Jing Ru
Published: July 2024

With the continuous improvement of China’s current technology level, the Internet of Things (IoT) technology is also increasingly widely used in various fields. IoT is a network composed of electronic components, software, sensors, etc. With the development of IoT technology, users’ demand for remote control equipment is increasingly urgent. In this article, the genetic algorithm–backpropagation neural network (GA–BPNN) algorithm was deeply studied by combining genetic algorithm (GA) and backpropagation neural network (BPNN) algorithm, and its application in network security evaluation was discussed. This article mainly studied the security and remote control technology of computer network and applied it to intelligent agriculture. In the evaluation performance test of the GA–BPNN algorithm, the evaluation accuracy of GA, BPNN, and GA–BPNN under simple difficulty was 99.58, 99.15, and 99.92%, respectively, and the evaluation accuracy under difficulty was 96.72, 96.47, and 98.88%, respectively. This proved the effectiveness of the GA–BPNN algorithm. In addition, in the application of smart agriculture, through the experimental data and concentration change data, it can be seen that the use of air-driven

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. Through the analysis of the system’s light compensation system, it was proved that the system has a good structure and remarkable light compensation effect; it can replenish light for crops in time, and the PLC control structure has good working performance. The correctness of the system design was proved.
Clinical and pharmacogenetic features of patients with upper gastrointestinal lesions at a multidisciplinary hospital: the role of nonsteroidal anti-inflammatory drugs
Authors: Denisenko Natalia P. , Zhiryakova Anna S. , Sychev Ivan V. , Kryukov Alexander V. , Tuchkova Svetlana N. , Vakulenko Olga Y. , Averkov Oleg V. , Vechorko Valery I. , Mirzaev Karin B. , Sychev Dmitry A.
Published: July 2024

Objectives

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed medications, but their use can be associated with a number of adverse reactions, including upper gastrointestinal lesions. The aim of the study was to identify clinical and pharmacogenetic factors associated with upper gastrointestinal lesions, including those linked to NSAIDs, in patients at a multidisciplinary hospital.

Methods

The study included 92 patients (mean age 59.4±16.5 years; 47 women), who underwent esophagogastroduodenoscopy during inpatient treatment. Patients’ intake of NSAIDs and gastroprotectors during the year before hospitalization was considered. Demographic, clinical, laboratory data of patients were compared between groups, including genotyping for CYP2C9*2 rs179985, CYP2C9*3 rs1057910, CYP2C8*3 rs11572080, CYP2C8*3 rs10509681, PTGS-1 rs10306135, PTGS-1 rs12353214, and PTGS-2 rs20417 using real-time PCR.

Results

In NSAIDs+ patients, PTGS1 rs10306135 AT+TT genotypes increased the chance of developing gastrointestinal complications by 5.4 times (95 % CI=1.30–22.27). In total sample, smoking (OR=3.12, 95 % CI=1.15–8.46), and alcohol intake (OR=4.09, 95 % CI=1.05–15.87) increased odds of gastrointestinal damage. In NSAIDs+ patients omeprazole, famotidine and both famotidine and omeprazole during the last year were as ineffective as not taking gastroprotectors; in total sample famotidine (OR=0.19, 95 % CI=0.04–0.93) and two gastroprotectors (OR=0.13, 95 % CI=0.02–0.75) reduced the chance of upper gastrointestinal lesions.

Conclusions

Pharmacogenetic features of patients may significantly contribute to the development NSAIDs-induced upper gastrointestinal injuries.
Analysis of green energy regeneration system for Electric Vehicles and Re estimation of carbon emissions in international trade based on evolutionary algorithms
Authors: Gao Zhongpo , Yu Ao
Published: July 2024

In order to achieve maximum carbon reduction during the operation of pure electric buses, the author proposes a re estimation of carbon emissions in international trade based on evolutionary algorithm analysis of electric vehicle green energy regeneration systems. On the basis of analyzing single line scheduling, the author focuses on studying the regional scheduling mode of pure electric buses, and establishes a multi-objective optimization model for pure electric bus regional scheduling considering carbon benefits with the goals of minimizing the number of operating vehicles, minimizing the empty distance, and maximizing carbon benefits. Based on the actual operation data of pure electric buses 146 and 149 in a certain city, the author used an improved particle swarm optimization algorithm to solve the regional scheduling problem of pure electric buses according to the characteristics of the model. The results indicate that assuming other conditions remain unchanged, when the price of diesel rises to around 7.9 yuan, its operating costs will exceed those of pure electric buses, and the cost advantage of diesel vehicles will gradually decrease. Other conditions remain unchanged, and when the battery price per vehicle drops to around 300,000 yuan, the operating cost of pure electric buses will be lower than that of diesel vehicles. Conclusion: Under the premise of considering carbon benefits, adopting regional dispatch mode for pure electric buses has better economic efficiency and is more conducive to the promotion of pure electric buses.
Foundations of causal discovery on groups of variables
Authors: Wahl Jonas , Ninad Urmi , Runge Jakob
Published: July 2024

Discovering causal relationships from observational data is a challenging task that relies on assumptions connecting statistical quantities to graphical or algebraic causal models. In this work, we focus on widely employed assumptions for causal discovery when objects of interest are (multivariate) groups of random variables rather than individual (univariate) random variables, as is the case in a variety of problems in scientific domains such as climate science or neuroscience. If the group level causal models are derived from partitioning a micro-level model into groups, we explore the relationship between micro- and group level causal discovery assumptions. We investigate the conditions under which assumptions like causal faithfulness hold or fail to hold. Our analysis encompasses graphical causal models that contain cycles and bidirected edges. We also discuss grouped time series causal graphs and variants thereof as special cases of our general theoretical framework. Thereby, we aim to provide researchers with a solid theoretical foundation for the development and application of causal discovery methods for variable groups.
Der Einfluss der Messunsicherheit in der Materialprüfung – Von der Messmittelauswahl zur Konformitätsaussage am Beispiel des Zugversuchs bei erhöhter Temperatur nach DIN EN ISO 6892-2:2018-09
Authors: Wieler Stefan , Frenz Holger
Published: July 2024

Kurzfassung

Für Prüflabore ist eine Aussage zur Konformität, ihrer Mess- und Prüfergebnisse gegenüber einer Spezifikationsanforderung stets mit dem Risiko einer falschen Annahme oder Ablehnung verbunden. Entscheidenden Einfluss, wie groß dieses statistische Risiko ist, hat neben dem eigentlichen Messwert die zugehörige Messunsicherheit. Daher haben Prüflaboratorien ein vitales Interesse daran, die Messunsicherheit fachlich angemessen zu ermitteln und ggf. zu minimieren. Dazu bildet die Auswahl geeigneter Mess- und Prüfeinrichtungen die Grundlage, um Ergebnisse möglichst präzise und genau, aber auch vergleichbar und reproduzierbar zu ermitteln. In diesem Beitrag wird ein konkretes Beispiel aus der Materialprüfung am Beispiel des Zugversuchs an metallischen Werkstoffen bei erhöhter Temperatur nach DIN EN ISO 6892-2:2018-09 vorgestellt. Diese international harmonisierte Prüfnorm gibt Anforderungen an die einzusetzende Temperaturmesseinrichtung, hinsichtlich der zulässigen Abweichung und Messunsicherheit, vor. Zusammen mit den Kompetenzanforderungen aus DIN EN ISO/IEC 17025:2018-03, der Norm, die zusammen mit weiteren Regelwerken zur Akkreditierung von Prüflaboren herangezogen wird, ergeben sich weitere Anforderungen an die nachgewiesene, metrologische Rückführbarkeit und die Messunsicherheit. Fragen zu notwendigen Kalibrierintervallen und Wartungen runden den Informationsbedarf über Mess- und Prüfgeräte ab. Die damit verbleibenden Freiheitsgrade für die Anwender in Bezug auf die Auswahl der Temperaturmesseinrichtung werden weiter beschränkt, wenn für die Konformitätsaussage eine entsprechend geringe Messunsicherheit erforderlich ist. Der Beitrag beinhaltet konkrete Beispiele aus der Praxis zum Einfluss der Messunsicherheit der Temperaturmessung im Zugversuch nach DIN EN ISO 6892-2. Es werden sowohl die Herausforderungen an die Prüflaboratorien als auch mögliche Lösungsansätze aufgezeigt.
Detection of Memory Engrams in Mammalian Neuronal Circuits
Authors: Niewinski Nicole E. , Hernandez Deyanell , Colicos Michael A.
Published: July 2024

It has long been assumed that activity patterns persist in neuronal circuits after they are first experienced, as part of the process of information processing and storage by the brain. However, these “reverberations” of current activity have not been directly observed on a single-neuron level in a mammalian system. Here we demonstrate that specific induced activity patterns are retained in mature cultured hippocampal neuronal networks. Neurons within the network are induced to fire at a single frequency or in a more complex pattern containing two distinct frequencies. After the stimulation was stopped, the subsequent neuronal activity of hundreds of neurons in the network was monitored. In the case of single-frequency stimulation, it was observed that many of the neurons continue to fire at the same frequency that they were stimulated to fire at. Using a recurrent neural network trained to detect specific, more complex patterns, we found that the multiple-frequency stimulation patterns were also retained within the neuronal network. Moreover, it appears that the component frequencies of the more complex patterns are stored in different populations of neurons and neuron subtypes.
The Role of the Medial Prefrontal Cortex in Spatial Margin of Safety Calculations
Authors: Qi Song , Cross Logan , Wise Toby , Sui Xin , O’Doherty John , Mobbs Dean
Published: July 2024

Naturalistic observations show that animals pre-empt danger by moving to locations that increase their success in avoiding future threats. To test this in humans, we created a spatial margin of safety (MOS) decision task that quantifies pre-emptive avoidance by measuring the distance subjects place themselves to safety when facing different threats whose attack locations vary in predictability. Behavioral results show that human participants place themselves closer to safe locations when facing threats that attack in spatial locations with more outliers. Using both univariate and multivariate pattern analysis (MVPA) on fMRI data collected during a 2 h session on participants of both sexes, we demonstrate a dissociable role for the vmPFC in MOS-related decision-making. MVPA results revealed that the posterior vmPFC encoded for more unpredictable threats with univariate analyses showing a functional coupling with the amygdala and hippocampus. Conversely, the anterior vmPFC was more active for the more predictable attacks and showed coupling with the striatum. Our findings converge in showing that during pre-emptive danger, the anterior vmPFC may provide a safety signal, possibly via foreseeable outcomes, while the posterior vmPFC drives unpredictable danger signals.
Synaptic Connectivity and Electrophysiological Properties of the Nucleus of the Lateral Olfactory Tract
Authors: Penker Sapir , Lawabny Naheel , Dhamshy Aya , Licht Tamar , Rokni Dan
Published: July 2024

The sense of smell is tightly linked to emotions, a link that is thought to rely on the direct synaptic connections between the olfactory bulb (OB) and nuclei of the amygdala. However, there are multiple pathways projecting olfactory information to the amygdala, and their unique functions are unknown. The pathway via the nucleus of the lateral olfactory tract (NLOT) that receives input from olfactory regions and projects to the basolateral amygdala (BLA) is among them. NLOT has been very little studied, and consequentially its function is unknown. Furthermore, formulation of informed hypotheses about NLOT function is at this stage limited by the lack of knowledge about its connectivity and physiological properties. Here, we used virus-based tracing methods to systematically reveal inputs into NLOT, as well as NLOT projection targets in mice of both sexes. We found that the NLOT is interconnected with several olfactory brain regions and with the BLA. Some of these connections were reciprocal, and some showed unique interhemispheric patterns. We tested the excitable properties of NLOT neurons and the properties of each of the major synaptic inputs. We found that the NLOT receives powerful input from the piriform cortex, tenia tecta, and the BLA but only very weak input from the OB. When input crosses threshold, NLOT neurons respond with calcium-dependent bursts of action potentials. We hypothesize that this integration of olfactory and amygdalar inputs serves behaviors that combine smell and emotion.
Voltammetric Detection of Diclofenac with Screen-printed Electrodes Based on Graphene and PVDF-Modified Graphene
Authors: Paunović Perica , Grozdanov Anita , Dimitrievska Iva , Tomova Ana
Published: July 2024

In recent years, the detection and determination of numerous drugs and pharmaceuticals in various media have become crucial aspects of modern healthcare and environmental management. Among the available sensing techniques, electrochemical methods, particularly those utilising screen-printed electrodes (SPEs) and different portable equipment have emerged as rapid, effective, sensitive, and inexpensive. This study focuses on the detection of the anti-inflammatory drug diclofenac in neutral media. Cyclic voltammetry measurements were conducted to identify diclofenac and determine the kinetics and electrochemical mechanism of its oxidation, along with assessing the surface characteristics of the employed SPEs. Graphene and modified graphene SPEs were explored as nanosensors for this purpose. The surface of the graphene SPE was modified using polyvinylidene fluoride, applied through a drop modification procedure. The morphology of the examined SPEs was observed by means of scanning electron microscope, while the electrolyte (0.1 g of diclofenac per litre of phosphate-buffered solution, pH = 7.4) was analysed using UV-Vis spectroscopy. The results indicate that the studied SPEs exhibit promising potential for the detection of diclofenac.