bluuebunny/crossref_metadata_2025 huggingface dataset:
Preliminary Evidence of the Use of Generative AI in Health Care Clinical Services: Systematic Narrative Review (Preprint)
Authors: Yim Dobin , Khuntia Jiban , Parameswaran Vijaya , Meyers Arlen
Published: August 2023

BACKGROUND

Generative artificial intelligence tools and applications (GenAI) are being increasingly used in health care. Physicians, specialists, and other providers have started primarily using GenAI as an aid or tool to gather knowledge, provide information, train, or generate suggestive dialogue between physicians and patients or between physicians and patients’ families or friends. However, unless the use of GenAI is oriented to be helpful in clinical service encounters that can improve the accuracy of diagnosis, treatment, and patient outcomes, the expected potential will not be achieved. As adoption continues, it is essential to validate the effectiveness of the infusion of GenAI as an intelligent technology in service encounters to understand the gap in actual clinical service use of GenAI.

OBJECTIVE

This study synthesizes preliminary evidence on how GenAI assists, guides, and automates clinical service rendering and encounters in health care The review scope was limited to articles published in peer-reviewed medical journals.

METHODS

We screened and selected 0.38% (161/42,459) of articles published between January 1, 2020, and May 31, 2023, identified from PubMed. We followed the protocols outlined in the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines to select highly relevant studies with at least 1 element on clinical use, evaluation, and validation to provide evidence of GenAI use in clinical services. The articles were classified based on their relevance to clinical service functions or activities using the descriptive and analytical information presented in the articles.

RESULTS

Of 161 articles, 141 (87.6%) reported using GenAI to assist services through knowledge access, collation, and filtering. GenAI was used for disease detection (19/161, 11.8%), diagnosis (14/161, 8.7%), and screening processes (12/161, 7.5%) in the areas of radiology (17/161, 10.6%), cardiology (12/161, 7.5%), gastrointestinal medicine (4/161, 2.5%), and diabetes (6/161, 3.7%). The literature synthesis in this study suggests that GenAI is mainly used for diagnostic processes, improvement of diagnosis accuracy, and screening and diagnostic purposes using knowledge access. Although this solves the problem of knowledge access and may improve diagnostic accuracy, it is oriented toward higher value creation in health care.

CONCLUSIONS

GenAI informs rather than assisting or automating clinical service functions in health care. There is potential in clinical service, but it has yet to be actualized for GenAI. More clinical service–level evidence that GenAI is used to streamline some functions or provides more automated help than only information retrieval is needed. To transform health care as purported, more studies related to GenAI applications must automate and guide human-performed services and keep up with the optimism that forward-thinking health care organizations will take advantage of GenAI.
Proposing a person-centred decentralised health data ecosystem to optimise applied data science and artificial intelligence for dementia prevention and cognitive longevity. (Preprint)
Authors: Albertyn Christopher , Surodina Svitlana , Tan Bo , Woods Tina , Corner Lynne , Aarsland Dag , Siow Richard
Published: August 2023

UNSTRUCTURED

Global healthcare systems need to evolve to ensure optimal, safe, and ethical utilisation of health data and the latest digital technologies, such as Artificial Intelligence (AI), Privacy Enhancing Technologies (PETs), and Distributed Ledger Technologies (DLTs), to meet the challenges of a global ageing population. Simultaneously, the increasing capabilities of remote measurement technologies and the proliferation of 5G networks demonstrates that digital technologies are now more accessible to a much larger population, offering an opportunity for decentralised democratised health data use that supports individual agency. Given the significant international human and economic cost of cognitive decline and dementia, we propose that a person-centred decentralised health data ecosystem, underpinned by these emerging technologies and opportunities, would reduce burden on cognitive healthcare systems by intervening earlier, accelerate clinical research innovation in dementia, and extend cognitive healthspan. Crucially, we argue for the importance of including the individual, as well as other key stakeholders, in the development, continuing operation, and as a shared beneficiary of any potential accrued value emerging from this ecosystem.
Syntactic Metaphors as Common Features of Most Nigerian Indigenous Names
Authors: Ph.D. Anthony JAMES, , SONGDEN, Ph.D. Rejoice James , Saina’an LAGAN Mrs. Blessing , OJO Mrs. Onome
Published: August 2023

African names are reflections of many factors at work, because beyond the fact that they identity symbols, the indigenous Nigerian Society believes that names shape a person’s character, mold their social identity and even influence an individual’s destiny. This explains why this study examined the peculiarities associated with most Nigerian indigenous names, focusing especially on the syntactic features of these names. The names used in this study were drawn from the two major Nigerian Languages of Yoruba and Igbo, and the third language, is the Edo Language of the Benin Kingdom. Consequently, when these names were translated into the English Language, using the parsing tools of Systemic Grammar of S- Subject, P- Predicator, C- Complement and A- Adjunct, the findings revealed that while most Nigerian indigenous names are singular words in their native entities, when these names are translated into English Language and analysed, they are complete sentences in the shape of subject, predicator and complement or subject, predicator and adjunct, in some cases a subject and a predicator. The findings buttress the fact that Nigerian indigenous names are classics, because they are like film – reels that reveal the cosmopolitan world view of the Nigerian indigenous societies. This highlights why these meanings are connotatively metaphoric, because a peoples thought, experience and what they do every day is very much a matter of metaphor (Lakoff and Johnson 1980: 3).
Carbon Trading in BRICS Countries: Challenges and Recommendations
Authors: Zhang Fangyuan , Zhao Ruixi , Yang Yizhou , Zou Xiaolong
Published: August 2023

As one of the world’s largest emerging economies, BRICS countries are playing an increasingly important role in addressing the global issue of climate change. To achieve their emissions reduction targets, these nations are actively promoting the construction of carbon trading markets. However, they face multiple challenges and obstacles in this endeavor, including issues related to market norms, financial support, technical capacity, social participation, and development needs. This research investigates the problems and challenges faced by BRICS countries in terms of building carbon trading markets through literature reviews and case studies. To address these challenges, this research strengthening international cooperation and technical support, improving market norms and provide following recommendations: conducting regulatory measures, enhancing social participation and communication, and balancing the relationship between economic development and environmental protection requirements. Furthermore, it is crucial for these nations to continue to strengthen international cooperation and collaboration, working together to promote the construction of carbon trading markets, achieving their emissions reduction targets, and ensuring long-term sustainability and economic development.
The U.S. Toilet Paper Market: A Competitive Profile
Authors: Datta Y.
Published: August 2023

This is the fourteenth paper that follows the footsteps of thirteen studies that have tried to analyze the competitive profiles of U.S. consumer markets: Men’s Shaving Cream, Beer, Shampoo, Shredded/Grated Cheese, Refrigerated Orange Juice, Men’s Razor-Blades, Women’s Razor-Blades, Toothpaste, Canned Soup, Coffee, Potato Chips, Alkaline AA Batteries, and Facial Tissue.Michael Porter associates high market share with cost leadership strategy, which is based on the idea of competing on a price that is lower than that of the competition.However, customer-perceived quality—not low cost—should be the underpinning of competitive strategy, because it is far more vital to long-term competitive position and profitability than any other factor. So, a superior alternative is to offer better quality vs. the competition.In most consumer markets, a business seeking market share leadership should try to serve the middle class by competing in the mid-price segment; and offering quality better than that of the competition: at a price somewhat higher to signify an image of quality, and to ensure that the strategy is both profitable and sustainable in the long run. Quality, however, is a complex concept, consumers generally find difficult to understand. So, they often use relative price, and a brand’s reputation, as a symbol of quality.The 2008 net sales for the Toilet Paper market were $4,117 million. By far the most popular pack size was the 12-roll pack which constituted 38% of total sales. So, we have concentrated our statistical analysis on that size.For 2008 we found 25 brands with 12‑roll sales over $70,000. However, three of those brands had no sales for 2007. So, we had to restrict our analysis to the remaining 22 for both years.Using Hierarchical Cluster Analysis, we tested two hypotheses: (I) That the market leader is likely to compete in the mid-price segment, and that (II) Its unit price is likely to be higher than that of the nearest competition.For both 2008 and 2007, the results did not support Hypothesis I. This is because both Charmin, the market leader, and Kleenex Cottonelle, the runner-up, were found to be members of the premium segment.However, the data supported Hypothesis II, because the unit price of Charmin was higher than that of (Kleenex) Cottonelle.We found that relative price was a strategic variable, as hypothesized.A pattern is emerging in price-quality segmentation analysis. In ten of the fourteen studies—that exclude Men’s and Women’s Razor-Blades, Ground Coffee, and Toilet Paper—the market leader was found to be a member of the mid-price segment, as we have hypothesized.Moreover, results in seven markets supported Hypothesis II.We also discovered four strategic groups in the industry.
La sociología implícita en la teoría pura del derecho
Authors: Gómez Yuri Hernán
Published: August 2023

An attempt is made to establish the place of sociological analysis within the scheme of Kelsen’s pure theory. In this respect, it is argued that the proposal of an exclusively normative approach to law rests on a set of empirical conditions, on the verification of which the very possibility of assuming the Grundnorm of a system depends. Thus, when it comes to identifying something as law, it becomes necessary to examine the overarching relationship between validity and efficacy. But this can only be done by including knowledge beyond the legal science, that is, of a political and sociological nature. Correspondingly, this paper begins by presenting the ontological split between Sein and Sollen adopted by Kelsen as the basis for his methodological distinction between empirical and normative sciences. Then, this distinction is questioned from the perspective of the requirement of efficacy imposed on the validity of law, so as to finally arrive to the work’s conclusion. That is, that the pure theory presupposes a certain sociology in order to determine its own subject of study.
Legal protection of employee wage rights in bankrupt companies: evidence from China
Authors: Jaelani Abdul Kadir , Nuryanto Ahmad Dwi , Fenitra Rakotoarisoa Maminirina , Mujib M. Misbahul , Luthviati Resti Dian
Published: August 2023

This study aims to identify the factors contributing to the legal protection of workers' wage rights in bankrupt companies in China, focusing on aspects that have not been grounded in social justice. This research is also to formulate and form a legal protection model for workers' wage rights in bankrupt companies based on social justice in Indonesia and China. This research is empirical. The research data is in the form of primary and secondary data (primary and secondary legal materials). The study results show that the factors that cause legal protection of workers' wage rights in bankrupt companies are not based on social justice and are the legal substance factor, namely the legal norms governing workers' wage rights and other rights. When a company goes bankrupt, there is non-uniformity in the priority hierarchy of creditors in the Bankruptcy Law, General Provisions on Tax Implementation Procedures, and Labor Laws. Another factor is the legal and structural factor, which only involves the trustee and supervisory judges in the settlement of bankrupt assets. The last factor is the legal culture, where participation in the payment of bankruptcy assets is minimal and the current economic system tends to be capitalist. Indonesia must take the Chinese government as an example; China places a premium on modifying labour standards to safeguard the rights and interests of workers in all circumstances and promote economic and social development.
Effect of microparticulate from whey protein concentrates on the characteristics of fresh cheese
Authors: Bejarano-Toro Edinson Eliecer , Rodríguez-Sandoval Eduardo , Sepúlveda-Valencia José Uriel
Published: August 2023

Whey, obtained from cheese manufacturing, has a significant environmental impact due to its organic load and volume produced. Therefore, validating technologies that allow its valorization due to its content of ingredients of high nutritional or functional value becomes relevant for the dairy industry. Microparticulate whey protein (MWP) has been used to produce cheeses and has the potential to improve process performance. We seek to develop and optimize the characteristics of a MWP to be used to make white cheese. For this, factors such as temperature, from 73  to 93°C, and retention time from 3 to 17 min of the heat treatment were evaluated. We assessed zeta potential, particle size, color, protein retention coefficient, and cheese yield as response variables using a response surface design with 14 experiments. Optimum conditions were 93°C for 5.4 min retention. In the white cheese production, two inclusion percentages were tested: 3 and 5% (w/w); and the impact on characteristics like yield, protein retention, and texture was evaluated with respect to a control cheese that was not added with MWP. We found that 3% inclusion is more suitable because it keeps textural characteristics closer to traditional cheese. The MWPs add value to whey and cheese by improving performance and enabling the retention of proteins of high biological and nutritional value.
Public space and the public that frequents it: dilemmas of the human rights to water and sanitation
Authors: Moreira Fernanda Deister , Fonseca Paula Rafaela Silva , Heller Léo , Rezende Sonaly
Published: August 2023

The human rights to water and sanitation were officially recognized by the United Nations in 2010. Despite this, these rights have not been explicitly recognized as basic rights in Brazilian legislation and their interpretation in law comes from the concept of universal access. However, little is discussed regarding the universalization of this access in spaces beyond the household, particularly in public spaces, serving people in socio-spatial vulnerability and who need urban furniture such as drinking fountains and toilets, either because they work or live there. It is in public spaces that homeless people, street vendors, women and girls, people with disabilities and transgender people are neglected, given the lack of access to water and public toilets. Thus, this work has sought to understand the possibilities of interpreting public sanitation policy in Brazil from the definitions of “universal access” and “household” using content analysis when reading these documents. It was concluded that the Law excludes public spaces, neglecting the aforementioned groups.
Analisis Strategi Menu Engineering dalam Upaya Meningkatkan Pendapatan Restaurant
Authors: Putra Ida Bagus Wijaya Dharma , Astina Made Arya , Putra Ida Bagus Wijaya Dharma , Arnawa I Gusti Made Suka
Published: August 2023

Penelitian ini dilaksanakan untuk membantu pihak manajemen dalam mengevaluasi dan menganalisis menu a’la carte menggunakan metode menu engineering. Pihak manajemen belum menerapkankan analisis menu menggunakan metode tersebut, sehingga pendapatan kurang maksimal. Penelitian ini bertujuan untuk mengetahui klasifikasi menu, dan diikuti dengan strategi untuk menindak lanjuti menu dengan klasifikasi tersebut. Penelitian ini dilaksanakan di The Sayan House Restaurant yang dilaksanakan pada bulan Maret 2021 –Juni 2021, dengan menggunakan sales history dari bulan Desember 2020 – Februari 2021. Jenis penelitian ini adalah deskriptif kualitatif dan kuantitatif. Penelitian ini menggunakan sampel jenuh sebanyak 38 item menu. Data dikumpulkan dari wawancara dan studi dokumentasi, kemudian dianalisis menggunakan teknik analisis menu engineering, sehingga mendapatkan klasifikasi menu yaitu star, plow horse, puzzle, dan dog. Hasil penelitian menunjukkan dari 38 item menu yang dianalisis, 16 diantaranya dikategorikan star, 10 diantaranya dikategorikan plow horse, 5 diantaranya dikategorikan puzzle, dan 7 diantaranya dikategorikan dog. Berdasarkan hasil analisis tersebut dan menyikapi masing-masing klasifikasi menu, diperlukan strategi dan tindak lanjut untuk setiap klasifikasinya, serta melakukan evaluasi menu secara rutin oleh pihak manajemen The Sayan House Restaurant.
 
This research was conducted to assist management in evaluating and analyzing a'la carte menu usingthe menu engineering method. The management has not implemented menu analysis using that method, so the revenue is less than maximum. This study aims to know the classification of the menu, and followed by a strategy to follow up the menu with that classification. This research was conducted at The Sayan House Restaurant conducted in March 2021 – June 2021, using sales history from December 2020 – February 2021. This type of research is descriptive qualitative and quantitative. The study used saturated samples of 38 menu items. The data is collected from interviews and documentation studies, then analyzed using engineering menu analysis techniques, to obtain menu classifications namely star, plow horse, puzzle, and dog. The results showed from 38 menu items analyzed, 16 of them were categorized as a star, 10 of them were categorized as a plow horse, 5 of them were categorized as a puzzles, and 7 of them were categorized as a dogs. Based on the results of the analysis and addressing each menu classification, strategy and follow-up for each classification are required, as well as conducting regular menu evaluations by the management of The Sayan House Restaurant.
Successful Management of Diabetes Mellitus (Madhumeha) With Ayurvedic Modalities (Vaman & Madhutailik Basti) – A Case Study
Authors: Balpande Khushhali , Wajpeyi Sadhana Misar
Published: August 2023

Ayurveda, an ancient medical system, is becoming more popular as a supplemental and alternative therapy for treatingchronic illnesses. Type 2 diabetes is a chronic condition with serious long-term effects on both the people who have it and thehealthcare system as a whole. Ayurvedic classics have twenty types PramehaKaphaj prameha 20, Pittaja prameha 6, and Vatajaprameha 4. Among this type, Diabetes mellitus is compared with Madhumeha, which is one of the Vataja types of Prameha. It is aKledapradhan vyadhi which is associated with excessive urination. The primary causes of the illness are an excessive intake ofdairy products, sugar products, rice, and seafood, an excessive amount of sleep, and a lack of activity. Various complications ofDiabetes mellitus include nephropathy, neuropathy, retinopathy, and cardiovascular disease. A 51-year-old female patient visitedOPD with chief complaints of Sweetness in her mouth, excessive hunger, thirst, urine, and burning sensation at the sole formore than 3 months, and other associated complaints were excessive mental stress and lethargy for the last 1 month. She wastreated with panchakarma treatment like Vaman, Madhutailik basti, and Shaman chikitsa like Nishamalaki churna and Madhunashinivati. Reduction in blood sugar level was observed at the end of treatment. Hence it can be concluded that shodhan and shamanchikitsa is beneficial in treating symptoms of Madhumeha.
Bamboo Plantations for Phytoremediation of Cadmium in Tannery Effluent: Plant Response and Nutrient Uptake
Authors: Arumugam Vidhya , Kalaivani R.
Published: August 2023

The rapid development of the industrial sector led to a greater level of heavy metal Cadmium in recent years. Food and breathing are the primary waysthat Cadmium enters the body. Humans are exposed to long-term health hazards from Cadmium. Cadmium accumulates in immune cells, triggers inflammatoryresponses, and leads to a number of health problems. Compared to conventional physical and chemical techniques, phytoremediation is a useful, environmentallyadvantageous method of remediating contaminated soil. Among the different approaches available for phytoremediation, Phytoextraction is the most effective andsuccessful method since it gets rid of heavy metals. Some bamboo species have been recognized as the most promising species for sequestering carbon andpotentially impacting the phytoremediation of soils contaminated with heavy metals. This study aims to assess the growth patterns of the native Indian bamboospecies (Bambusa bambos, Bambusa vulgaris, and Bambusa balcooa) when exposed to metal-contaminated water, such as tannery effluent, in the Tiruchirappalli area.The ability of bamboo sp. to phytoextract Cadmium from contaminated soil has been demonstrated through experimentation, and its antimicrobial and anti-cancerpotency is tested after being subjected to phytoextraction since the heavy metals in the tannery effluent are predominantly carcinogenic. The laboratory conducteda preliminary study on bamboo plant growth to gauge its growth. To measure the tolerance of bamboo when being rinsed with a solution containing 100 mg Cd/l,the morphological characteristics, heavy metal uptake, and translocation potential of the three bamboo species were assessed. The distribution of Cadmium indifferent fragments of the bamboo plant has also been studied, along with the factors that affect the uptake mechanism. Among the native species, Bambusa bambosis found to have a greater phytoextraction capacity of heavy metals, especially Cadmium. The plant is also evaluated for its anticancer and antimicrobial activitiesfollowing phytoextraction so that the stem and other parts of Bambusa bambos have been used as indigenous medicine by the tribal people, and this could be due tothe presence of flavonoids and other associated compounds present in it.
Study of Oral Squamous Cell Carcinoma with and without Oral Submucous Fibrosis.
Authors: Vinila B H Shiny , Vishali N , Gannepalli Ashalata
Published: August 2023

Oral submucous fibrosis (OSMF) is a precancerous condition associated with areca nut chewing. Arecoline which isa component of areca nut is considered a carcinogen. The OSMF in patients with oral squamous cell carcinoma (OSCC) indicatesareca nut-induced carcinogenesis. The molecular pathway for oral carcinogenesis caused by areca nut is discrete and considereda different clinicopathological entity. Thus the present study aims to study and compare the demographics, risk factors, and clinicalcharacteristics of OSCC patients with and without OSMF. It was a retrospective study done by medical record review. About 40OSCC cases were selected, of which 20 were with OSMF, and 20 were without OSMF. Demographic data, risk factors includinghistory of habits such as areca nut chewing, tobacco, etc., and clinical characteristics such as anatomical location, extent, tumorsize, and lymph node metastasis were noted, and data were analyzed. The mean age of OSCC cases with OSMF was younger thanthose without OSMF. The study groups did not observe a significant difference in habit type and duration. Most OSCC patientswith OSMF were younger than those OSCC without OSMF. The buccal mucosa was the most common anatomical locationinvolved with ulcers- proliferative growth in both study groups. The incidence of multiple sites and lymph node enlargementinvolvement is higher in OSCC without OSMF compared to those with OSMF. There was no significant difference concerninghistopathological changes between OSCC with and without the OSMF group.
Green Bond Financing for New Energy Power Cell Companies
Authors:   Asian Trade Association, Zheng Sisi
Published: August 2023

Purpose – As the global environmental pollution and energy crisis become increasingly serious, green finance has emerged as a crucial instrument for achieving sustainable development. The combination of the new energy industry and green bonds provides low-cost, long-term financial support for green and low-carbon projects, helping new energy companies develop and achieve China’s dual carbon goals. Design/Methodology/Approach – This study analyzes the issuance, financing drivers, and effects of the green bonds of Chinese new energy power battery companies using the event study method and financial analysis method, taking the issuance of green bonds by Findings – The main motivation for CATL to issue green bonds is to attract stakeholders, optimize the financing structure, and achieve sustainable development goals. The company has shown good market, financial, and environmental effects after issuing green bonds. Research Implications – This study combines green bonds with new energy industry financing, further enriching the concept of green finance and environmental governance theory. Further, it proposes four insights from information disclosure, investment group, regulatory mechanism, and enterprise level. The results of this study provide reference for new energy battery enterprises to carry out green bond financing, which is of certain significance to promote the healthy development of China’s green bond market.
Role of Necroptosis and Immune Infiltration in Atrial Fibrillation: Novel Insights Revealed by Integrated Computational Biology Analyses
Authors: Wang Danning , Wu Sumin , Zhu Ye
Published: August 2023

Background: Atrial fibrillation (AF) is associated with high
mortality and morbidity rates. In terms of the underlying
pathophysiology, AF is complex and remains unclear. Necroptosis plays an
essential role in the pathogenesis of various cardiovascular diseases.
This study aims to investigate the role of necroptosis and analyze the
interaction between necroptosis and AF. Methods: GSE79768 and
GSE41177 from the Gene Expression Omnibus (GEO) database were
downloaded, and necroptosis-related differentially expressed genes
(NRDEGs) were identified between AF and healthy groups. The Gene
Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG)
databases were then used to conduct functional enrichment analyses of
these genes. The CIBERSORT algorithm was used to reveal the patterns of
immune cell infiltration in AF and exam the correlation between hub
genes and immune cells to explain the underlying mechanism. Then, a
lncRNA-associated ceRNA network was constructed by using Cytoscape
underlying the interaction generated from the miRcode, miRTarBase, and
TarBase databases. Results: There were a total of 34 DEGs
identified. Necroptosis and inflammation were mainly controlled by these
DEGs. MAPK8, MAP3K7, CD40, CASP8, MYC, HSP90AA1, BCL2L11and DIABLO were
identified as the top 8 hub genes associated with AF. The relationship
between AF and the hub genes in patients was further confirmed in the
STRING database. The immune cell infiltration analysis indicated that B
cells memory, Eosinophil, T cells follicular helper, and Neutrophils
were significantly activated in atrial fibrillation. It was found that
the hub genes in GSE79768 were strongly correlated with immune cell
infiltration. B cells naïve and B cells memory, Plasma cells, and
Macrophages M2, T cells CD8 and Mast cells activated, Mast cells resting
and Mast cells activated showed a negative correlation (P
<0.01), Mast cells activated and Eosinophils, B cells memory
and T cells CD4 naïve showed a positive correlation (P <0.01).
Finally, 43 lncRNAs were identified in AF. Seven lncRNAs (SLFNL1-AS1,
LINC01132, PCBP1-AS1, LINC01816, LINC02035, MYLK-AS1, TERC) regulate the
hub-gene through has-mir-34c-5p. Conclusions: MAPK8, MAP3K7,
CD40, and CASP8 may act as critical regulators in the necroptosis of
cardiomyocytes in AF patients. It involves mechanisms such as humoral
immunity, cellular immunity, and inflammatory response, but the
fundamental biological function of these genes remains unclear. Our
present study may pave the way for further research into the necroptosis
of AF.
Akışkan Yatak Kurutma Prosesi İçin Isı Pompalı Ön Isıtmanın Termoekonomik Analizi
Authors: Şensoy Buğra , Aktaş Mustafa , Durak Veysel , Baran Tanrıkulu Zahide , Mergen Merve , Ulular Merve
Published: August 2023

Enerji verimliliği, küresel ısınma ve iklim değişikliği günümüzde üzerinde durulan en önemli konuların başında gelmektedir. Tüketilen enerjinin etkin ve verimli kullanımına ilişkin yeni tasarımlar yaparken de tasarımlarda kullanılacak yenilikçi ve verimli teknolojiler ekonomi ve çevresel olumsuz etkilerin azaltılmasına katkı sağlayacaktır. Bu çalışmada; tamamen gaz yakıcı bir cihazla çalışan döküm sektöründe kullanılan akışkan yataklı bir kum kurutma sistemine ısı pompası entegre edilerek doğalgaz tüketimi azaltılmaya ve bu sayede sistem kullanıcılarına doğrudan ve dolaylı kazanımlar yaratılmaya çalışılmıştır. Sudan suya çalışan ve çevre dostu R32 soğutucu akışkanı kullanılarak 20°C’deki ortam havasını 45°C’ye ön ısıtma yapacak şekilde tasarımı yapılan ısı pompası sisteminin performans katsayısı (COPIP) 3,88 olarak hesaplanmıştır. Isı pompası entegrasyonu sayesinde sistem yıllık 36.839,1 Nm3 doğalgaz tasarrufu gerçekleştirilecektir. Bu entegrasyon ile sistemin yıllık çalışma süresi, elektrik ve doğalgaz birim maliyetleri baz alınarak, işletmecisine 193.501,25 ₺/yıl mali tasarruf sağlayacağı öngörülmektedir. Sisteme entegre edilen ısı pompasının; ekipman ve kurulum fiyatı, güncel kur değeri ile yıllık mali tasarruf miktarı parametreleri dahilinde, sistemin amortisman süresi 1,50 yıl olarak hesaplanmıştır. Ayrıca sistemde kurulacak fotovoltaik paneller ile enerji üretilerek karbon emisyonunun azaltılabileceği ve yine fotovoltaik panellerin marifetiyle işletmeci firmaya ek bir gelir kalemi oluşturulabileceği de öngörülmektedir.
Incidence and Prevalence of 73 Different Genodermatoses: A Nationwide Study in Sweden
Authors: Zagoras Theofanis , Inci Rahime , Kantere Despoina , Holmström Peter , Broström Jenny , Gillstedt Martin , Polesie Sam , Peltonen Sirkku
Published: August 2023

This retrospective registry-based cohort study aimed to estimate the incidence and prevalence of genodermatoses in the Swedish population and to analyse associated healthcare usage. Patients diagnosed with genodermatoses were identified from the patient registry of Sahlgrenska University Hospital (Gothenburg, Sweden) between 2016 and 2020. Clinical data from medical records were used to verify diagnoses recorded in the National Patient Registry (NPR). The NPR was then searched for International Classification of Diseases, Tenth Revision (ICD-10) codes Q80–82 and Q84 from 2001 to 2020. The local cohort included 298 patients with 36 unique genodermatosis diagnoses. Verification of these diagnoses in the NPR showed positive predictive values of over 90%. The NPR search yielded 13,318 patients with 73 unique diagnoses, including ichthyoses (n = 3,341; 25%), porokeratosis (n = 2,277; 17%), palmoplantar keratodermas (n = 1,754; 13%), the epidermolysis bullosa group (n = 1011; 7%); Darier disease (n = 770; 6%), Hailey-Hailey disease (n = 477; 4%) and Gorlin syndrome (n = 402; 3%). The incidence and prevalence of each diagnosis were calculated based on the nationwide cohort and are reported. A total of 149,538 outpatient visits were registered, a mean of 4.6 visits per patient. This study provides a valuable resource for the epidemiology of genodermatoses by reporting on the incidence and prevalence of 73 different genodermatoses.
Diagnostical accuracy of hyperspectral imaging after free flap surgery
Authors: Schulz Torsten , Nuwayhida Rima , Houschyar Khosrow Siamak , Langer Stefan , Kohler Lukas
Published: August 2023

Microsurgical free-tissue transfer has been a safe option for tissue reconstruction. This study aimed to analyze the diagnostic accuracy of hyperspectral imaging (HSI) after free-tissue transfer surgery. From January 2017 to October 2019, 42 consecutive free-flap surgeries were performed, and their outcomes were analyzed via HSI. Clinical examination of free-flap perfusion was initially performed. Clinical examination findings were subsequently compared with those of HSI. Potential venous congestion with subsequent necrosis was defined as a tissue hemoglobin index of ≥53%. Student’s t-test was used to compare the results of the analysis. The evaluation of sensitivity and specificity for flap failure detection was time dependent using the Fisher’s exact test. A p-value of ≤0.05 was considered statistically significant. Microsurgical tissue transfer success rate was 84%. Seven patients presented with venous congestion that caused total flap necrosis. Overall, 124 assessments were made. HSI accurately identified 12 out of 19 pathological images: four as false positive and seven as false negative. The sensitivity and specificity of HSI were 57 and 94%, respectively, compared to those of clinical examination that were 28 and 100%, respectively, within 24 h following tissue transfer. The sensitivity and specificity of HSI were 63 and 96%, respectively, compared to those of clinical examination that were 63 and 100%, respectively, within the first 72 h. A tissue hemoglobin index of ≥53% could predict venous congestion after free-flap surgery. HSI demonstrated higher sensitivity than clinical examination within the first 24 h; however, it was not superior compared to clinical findings within 72 h.
Effect of very early supported discharge versus usual care on activi­ties of daily living ability after mild stroke: a randomized controlled trial
Authors: Björkdahl Ann , Rafsten Lena , Petersson Cathrine , S. Sunnerhagen Katharina , Danielsson Anna
Published: August 2023

Objective: To examine the ability to perform basic and instrumental activities of daily life after very early supported discharge vs usual discharge and referral routine during the first year after mild stroke.
Design: A secondary analysis of data from the Gothenburg Very Early Supported Discharge randomized controlled trial. 
Patients: A total of 104 patients (56% men; mean (standard deviation) age 75 (11) years) who had experienced a first stroke classified as mild.
Methods: The primary outcome was the Activities of Daily Living Taxonomy score. Stroke Impact Scale (activities of daily living, and mobility) scores was a secondary measure. Patients were randomized to either very early supported discharge with 4 weeks of home rehabilitation provided by a multidisciplinary stroke team, or a control group discharged according to usual routine (referral to primary care when needed). Assessments were performed at discharge, 4 weeks post-discharge, and 3 and 12 months post-stroke.
Results: Instrumental activities of the Activities of Daily Living Taxonomy scores (the lower the better) in the very early supported discharge and control groups were median 4 and 6 (p = 0.039) at 4 weeks post-discharge and 3 and 4.5 (p = 0.013 at 3 months post-stroke, respectively. Stroke Impact Scale (Mobility) median scores (the higher the better) in the very early supported discharge and control groups at 3 months were 97 and 86 (p = 0.040), respectively. There were no group differences in the 2 outcomes at 12 months post-stroke.
Conclusion: Compared with usual discharge routine, team-based rehabilitation during the first month at home is beneficial for instrumental activity in the subacute phase, in patients with mild stroke. One year post-stroke both groups show equal results.
Shoulder ultrasound imaging in the post-stroke population: a systematic review and meta-analysis
Authors: Lin Ting-Yu , Shen Peng-Chieh , Chang Ke-Vin , Wu Wei-Ting , Özçakar Levent
Published: August 2023

Objective: Post-stroke shoulder pain is a serious challenge for stroke survivors. The aim of this meta-analysis was to review the literature to confirm information on structural changes in post-stroke shoulders detected by ultrasound examination. Methods: PubMed, Embase, Web of Science and ClinicalTrials.gov were searched until 7 December 2022, for studies describing shoulder sonographic findings in stroke patients. Two independent authors selected the studies, extracted the data, and performed the critical appraisal. Results: A total of 23 clinical studies were included. The most prevalent pathologies in hemiplegic shoulders pertained to the biceps long head tendon (41.4%), followed by the supraspinatus tendon (33.2%), subdeltoid bursa (29.3%), acromioclavicular joint (15.0%), and subscapularis tendon (9.2%). The common pathological findings encompassed bicipital peritendinous effusion (39.2%), biceps tendinopathy (35.5%), subdeltoid bursitis (29.3%) and supraspinatus tendinopathy (24.6%). Biceps long head tendon and supraspinatus tendon abnormalities were observed significantly more in the hemiplegic (vs contralateral) shoulders, with odds ratios of 3.814 (95% confidence interval 2.044–7.117) and 2.101 (95% confidence interval 1.257–3.512), respectively. No correlation was observed between motor function and shoulder pathology. Conclusion: Ultrasonography enabled the identification of common shoulder pathologies after stroke. Further research is needed to establish the association between these changes and the clinical course of stroke patients.
Perspektiver på norsk oljepolitikk
Authors: Isachsen Arne Jon
Published: August 2023

Artikkelen er inspirert av et avisinnlegg skrevet av Auke Lont, Harald Norvik og Peter Melby der de tar til orde for at framtidige oljeinntekter bør går til klimatiltak i andre land i stedet for til ytterligere innskudd i det nåværende oljefondet. Artikkelen beskriver den norske oljepolitikken fra tidlig 1960-tall til i dag. Den har vært en udelt suksess som har tjent Norge godt. Men norsk oljeproduksjon har bidratt til store utslipp av CO2. Det er den moralske begrunnelsen for at framtidige norske oljeinntekter bør brukes til klimatiltak.
Abstract in English:Perspectives on Norwegian Oil Policy. Future Oil Income Should Be Used to Finance Climate Measures in Countries That Cannot Meet Paris Agreement Terms on Their OwnThe article is inspired by a newspaper article by Auke Lont, Harald Norvik and Peter Melby in which they proposed that income from future oil extraction should be spent on climate measures in other countries rather than being deposited in Norway’s petroleum fund. The article describes Norwegian oil policy from the early 1960s to present. It has been very successful and benefited Norway, yet Norwegian oil production has also contributed significantly to CO2 emissions. This is the moral justification for the suggestion that future Norwegian oil revenues should be used on climate measures.
Infant Button Battery Injury and Death (IBBID)
Authors: Paull John
Published: August 2023

Infant button battery injury and death (IBBID) is a known worldwide risk for pre-school age children. An ingested button battery that lodges in a child’s oesophagus will be fatal for the child if the button battery is not promptly removed. Button batteries of 20 mm diameter (e.g. CR2032) present a serious risk of such lodgement if ingested, they are in common usage (for example in many car key-fobs), and are readily available in supermarkets. Where such a button battery is removed (say by medical intervention) the child may be permanently disabled. It is the diameter of such button batteries (≥20 mm) that leads to lodgement and the electrical charge of such batteries that will cause tissue chemical burn, which, will likely be fatal if the burn creates a fistula (tunnel) through to an organ adjacent to the oesophagus (e.g., a tracheoesophageal fistula joins the windpipe and the gullet). Seven legal options for action are considered in the present paper, with ratings of cost, duration, and potential sources of funding (for the UK): Class action; Representative action; Individual action; Prevention of Future Death Report; Household insurance; Judicial review; and medical negligence. At present injured children ‘suffer in silence’ and some die, but if the harms of IBBID are sufficiently monetised, then it can be anticipated that the dangerous button batteries will price themselves out of the market and manufacturers and suppliers will seek alternatives (e.g. different size, different chemistry, different design).
Systematic Literature Review on Alternative Governance Arrangements for Resource Deficient Situations: Small Island Community-Based Ecotourism
Authors: Nurhasanah Isye Susana , Hudalah Delik , Van den Broeck Pieter
Published: August 2023

This paper builds on evidence of community participation in the form of capacity-building practices following the growing trend of ecotourism development that is exponentially penetrating small islands. With an emphasis on the discussion of governance and local community involvement in development processes, this paper uses a systematic literature review combined with bibliometric analysis to identify and explore the trajectories of key themes in research in the field of alternative governance of small island ecotourism from 1980-2021. Initially, we identified 572 papers that matched the selection criteria. After filtering, we found 22 articles that revolved around the governance of (community-based) ecotourism on small islands. Building on the review, we then examined the potential theoretical contributions to guide future research regarding the building of bottom-linked socially innovative governance of ecotourism on small islands in general, and the role of participation, community capacity building, (socio-political) emancipation and (political) bargaining power in particular.
Pelatihan Pembuatan Perjanjian untuk Menghindari Sengketa Hukum
Authors: Hartini Sri , Budiyono Budiyono , Haryanto Budiman Setya , Wakhid Nur
Published: August 2023

The lack Legal issues in the agreement process include leases, contracts, and accounts payable.Legal problems emerge due to carelessness and a lack of understanding of contract law. Lackof legal understanding has resulted in many fraud and embezzlement cases due to agreementsdisregarding a strong legal basis. Based on this phenomenon, the Community Service Team heldsocialization and education to reduce these problems. Implementing community service is carried out by the Blended method or a combination of implementation outside the network andwithin the network/offline and online. Online activities are carried out through zoom meetingsto provide material. Meanwhile, the practice of constructing legal agreements is carried out offline through face-to-face meetings with participants. Participants of community service are residents of Grendeng Village, Purwokerto. The service results show that before they get education about legal agreements, 90% of partners in contracting, leasing, buying, and selling do not use legal agreements and are only based on trust. The transfer of science and technology to partners regarding the complexities of the agreement includes rights, obligations, understanding, the meaning of the agreement, the purpose of the agreement, type of agreement, legal consequences, sanctions if violated, legal protection, settlement of agreement violations, and the practice of recognizing and making simple agreements directly. After holding community service, the partner understands the importance of agreements and can create simple agreements.
Habituasi Gerakan Maghrib Mengaji Pada Masyarakat Desa Pakkabba Kabupaten Takalar
Authors: Rahman Abdul
Published: August 2023

The Mahgrib Mengaji program was launched by the Ministry of Religion of the Republic of Indonesia on April 14, 2013. The program gets attention and good response from local governments in various regions of the Republic of Indonesia and continues today, including in the Takalar District. Along with the rate of development of technology, information, and communication, the community began to leave the Maghrib Mengaji program, including in Pakkabba Village, because the younger generation of the community put more engagement to social media and television shows. This community service activity aims to provide a deep understanding of the implementation of the Maghrib Mengaji program and create awareness of reading and practicing the contentsof the Quran. The community service team provides socialization and assistance to the Pakkabba Village community to habituate the Maghrib Mengaji program. Service activities are carried out by socializing the importance of reading the Quran and assisting Maghrib Mengaji habituation activities carried out from the house to house. Community service activities are carried out with socialization and assistance with the following stages: planning, implementation, monitoring, and administration. The activity results show that the people of Pakkabba Village have high enthusiasm for implementing the Maghrib Mengaji Program and getting support from the government and community leaders. Service activities received approval and support from the community, including the government and local community leaders.
Bakti Sosial dan Edukasi Masyarakat Terdampak Covid-19 di Kelurahan Pasir Kidul, Kecamatan Purwokerto Barat, Kabupaten Banyumas
Authors: Huda Ulul , Haryanto Budiman Setyo , Haryanto Tenang
Published: August 2023

The Covid-19 pandemic has had a broad impact on people worldwide, including Pasir Kidul Village, Purwokerto District, Banyumas. Community Service is conducted in two main activities: social service and community education. Social service activities are implemented by providing essential food subsidies to insufficient people affected by Covid-19, distributing masks, and spraying disinfectant liquid in the mosque area, public space, and the homes of residents of Pasir Kidul Village. Community education activities were held in four sessions with the following materials: Islamic understanding of Covid-19; Understanding of praying law in congregation during the Covid-19 pandemic; Understanding of health protocols related to the implementation of worship during the Covid-19 pandemic; and Materials regarding the burial of Covid-19 corpses. The activity results show that residents feel supported and have a good understanding of the practice of worship during the pandemic. Community service is a solution to real problems in the community who want to carry out various activities and worship activities without worrying about contracting the coronavirus.