bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of statin treatment on vasospasm-related morbidity and functional outcome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis
Authors: Shen Jian , Huang Kai-Yuan , Zhu Yu , Pan Jian-Wei , Jiang Hao , Weng Yu-Xiang , Zhan Ren-Ya
Published: October 2016

OBJECTIVE

The efficacy of statin therapy in treating aneurysmal subarachnoid hemorrhage (SAH) remains controversial. In this meta-analysis, the authors investigated whether statin treatment significantly reduced the incidence of cerebral vasospasm and delayed neurological deficits, promoting a better outcome after aneurysmal SAH.

METHODS

A literature search of the PubMed, Ovid, and Cochrane Library databases was performed for randomized controlled trials (RCTs) and prospective cohort studies investigating the effect of statin treatment. The end points of cerebral vasospasm, delayed ischemic neurological deficit (DIND), delayed cerebral infarction, mortality, and favorable outcome were statistically analyzed.

RESULTS

Six RCTs and 2 prospective cohort studies met the eligibility criteria, and a total of 1461 patients were included. The meta-analysis demonstrated a significant decrease in the incidence of cerebral vasospasm (relative risk [RR] 0.76, 95% confidence interval [CI] 0.61–0.96) in patients treated with statins after aneurysmal SAH. However, no significant benefit was observed for DIND (RR 0.88, 95% CI 0.70–1.12), delayed cerebral infarction (RR 0.66, 95% CI 0.33–1.31), mortality (RR 0.69, 95% CI 0.39–1.24) or favorable outcome, according to assessment by the modified Rankin Scale or Glasgow Outcome Scale (RR 0.99, 95% CI 0.92–1.17).

CONCLUSIONS

Treatment with statins significantly decreased the occurrence of vasospasm after aneurysmal SAH. The incidence of DIND, delayed cerebral infarction, and mortality were not affected by statin treatment. Future research should focus on DIND and how statins influence DIND.
Quantitative evaluation of vision-related and health-related quality of life after endoscopic transsphenoidal surgery for pituitary adenoma
Authors: Wolf Amparo , Coros Alexandra , Bierer Joel , Goncalves Sandy , Cooper Paul , Van Uum Stan , Lee Donald H. , Proulx Alain , Nicolle David , Alexander Fraser J. , Rotenberg Brian W. , Duggal Neil
Published: October 2016

OBJECTIVE

Endoscopic resection of pituitary adenomas has been reported to improve vision function in up to 80%–90% of patients with visual impairment due to these adenomas. It is unclear how these reported rates translate into improvement in visual outcomes and general health as perceived by the patients. The authors evaluated self-assessed health-related quality of life (HR-QOL) and vision-related QOL (VR-QOL) in patients before and after endoscopic resection of pituitary adenomas.

METHODS

The authors prospectively collected data from 50 patients who underwent endoscopic resection of pituitary adenomas. This cohort included 32 patients (64%) with visual impairment preoperatively. Twenty-seven patients (54%) had pituitary dysfunction, including 17 (34%) with hormone-producing tumors. Patients completed the National Eye Institute Visual Functioning Questionnaire and the 36-Item Short Form Health Survey preoperatively and 6 weeks and 6 months after surgery.

RESULTS

Patients with preoperative visual impairment reported a significant impact of this condition on VR-QOL preoperatively, including general vision, near activities, and peripheral vision; they also noted vision-specific impacts on mental health, role difficulties, dependency, and driving. After endoscopic resection of adenomas, patients reported improvement across all these categories 6 weeks postoperatively, and this improvement was maintained by 6 months postoperatively. Patients with preoperative pituitary dysfunction, including hormone-producing tumors, perceived their general health and physical function as poorer, with some of these patients reporting improvement in perceived general health after the endoscopic surgery. All patients noted that their ability to work or perform activities of daily living was transiently reduced 6 weeks postoperatively, followed by significant improvement by 6 months after the surgery.

CONCLUSIONS

Both VR-QOL and patient's perceptions of their ability to do work and perform other daily activities as a result of their physical health significantly improved by 6 months after endoscopic resection of pituitary adenoma. The use of multidimensional QOL questionnaires provides a precise assessment of perceived outcomes after endoscopic surgery.
Midline and off-midline infratentorial supracerebellar approaches to the pineal gland
Authors: Matsuo Satoshi , Baydin Serhat , Güngör Abuzer , Miki Koichi , Komune Noritaka , Kurogi Ryota , Iihara Koji , Rhoton Albert L.
Published: October 2016

OBJECTIVE

A common approach to lesions of the pineal region is along the midline below the torcula. However, reports of how shifting the approach off midline affects the surgical exposure and relationships between the tributaries of the vein of Galen are limited. The purpose of this study is to examine the microsurgical and endoscopic anatomy of the pineal region as seen through the supracerebellar infratentorial approaches, including midline, paramedian, lateral, and far-lateral routes.

METHODS

The quadrigeminal cisterns of 8 formalin-fixed adult cadaveric heads were dissected and examined with the aid of a surgical microscope and straight endoscope. Twenty CT angiograms were examined to measure the depth of the pineal gland, slope of the tentorial surface of the cerebellum, and angle of approach to the pineal gland in each approach.

RESULTS

The midline supracerebellar route is the shortest and provides direct exposure of the pineal gland, although the culmen and inferior and superior vermian tributaries of the vein of Galen frequently block this exposure. The off-midline routes provide a surgical exposure that, although slightly deeper, may reduce the need for venous sacrifice at both the level of the veins from the superior cerebellar surface entering the tentorial sinuses and at the level of the tributaries of the vein of Galen in the quadrigeminal cistern, and require less cerebellar retraction. Shifting from midline to off-midline exposure also provides a better view of the cerebellomesencephalic fissure, collicular plate, and trochlear nerve than the midline approaches. Endoscopic assistance may aid exposure of the pineal gland while preserving the bridging veins.

CONCLUSIONS

Understanding the characteristics of different infratentorial routes to the pineal gland will aid in gaining a better view of the pineal gland and cerebellomesencephalic fissure and may reduce the need for venous sacrifice at the level of the tentorial sinuses draining the upper cerebellar surface and the tributaries of the vein of Galen.
Characteristics of infarction after encephaloduroarteriosynangiosis in young patients with moyamoya disease
Authors: Kim Hyun Gi , Lee Seung-Koo , Lee Jung-Dong
Published: October 2016

OBJECTIVE

Young patients with moyamoya disease can exhibit infarction after revascularization surgery. This analysis of the characteristics of infarction after encephaloduroarteriosynangiosis (EDAS) in young patients with moyamoya disease was undertaken in an effort to elucidate the infarction mechanism.

METHODS

The authors retrospectively collected clinical information and reviewed pre- and postoperative MRI studies from cases involving patients younger than 18 years who underwent EDAS for the treatment of moyamoya disease between January 2012 and February 2015. Infarction patterns were categorized into watershed, territorial, or mixed pattern. The Wilcoxon rank sum test, chi-square test, and Fisher exact test were used to compare the clinical and imaging variables between patient groups. The characteristics of patients with and without postoperative infarction were compared using univariate and multivariate analysis. The cumulative proportion of patients without postoperative infarction according to operation stage was calculated using the Kaplan-Meier method and the resulting curves were compared using the log-rank test.

RESULTS

In 100 patients, 171 EDAS procedures had been performed. There were 38 cases of preoperative infarction in 35 patients and 20 cases of postoperative infarction in 13 patients. Territorial infarction was more frequent in the postoperative infarction group than in the preoperative infarction group (55.0% vs 37.8%, p = 0.037). Infarction was more common on the bilateral or contralateral side of the operation after first-stage EDAS (9 [75.0%] of 12 infarctions) than in the second-stage operation (2 [25.0%] of 8 infarctions), but the difference was not statistically significant (p = 0.068). The frequency of postoperative infarction was not significantly different depending on the stage of the operation (p = 0.694).

CONCLUSIONS

An acute infarction pattern after EDAS was more frequently territorial, suggesting an underlying occlusive mechanism. Operation stage did not affect the rate of postoperative infarction occurrence.
Rotational vertebrobasilar insufficiency due to compression of a persistent first intersegmental vertebral artery variant: case report
Authors: Buch Vivek P. , Madsen Peter J. , Vaughan Kerry A. , Koch Paul F. , Kung David K. , Ozturk Ali K.
Published: October 2016

Rotational vertebrobasilar insufficiency, or bow hunter's syndrome, is a rare cause of posterior circulation ischemia, which, following rotation of the head, results in episodic vertigo, dizziness, nystagmus, or syncope. While typically caused by dynamic occlusion of the vertebral artery in its V2 and V3 segments, the authors here describe a patient with dynamic occlusion of the vertebral artery secondary to a persistent first intersegmental artery, a rare variant course of the vertebral artery. In this case the vertebral artery coursed under rather than over the posterior arch of the C-1. This patient was also found to have incomplete development of the posterior arch of C-1, as is often seen with this variant. The patient underwent dynamic digital subtraction angiography, which demonstrated occlusion at the variant vertebral artery with head turning. He was then taken for decompression of the vertebral artery through removal of the incomplete arch of C-1 that was causing the dynamic compression. After surgery the patient had a complete resolution of symptoms. In this report, the authors present the details of this case, describe the anatomical variants involved, and provide a discussion regarding the need for atlantoaxial fusion in these patients.
Un scarabée avec inscription syllabique chypriote du premier millénaire au musée archéologique de Naples
Authors: Garcia-Ramon José Luis , Olivier Jean-Pierre , Perna Massimo
Published: October 2016

The present article concentrates on a scarab housed in the Archaeological Museum of Naples inscribed in the Cypriote syllabic script of the 1rst millennium. The authors demonstrate that the inscription contains six signs (instead of three, as previously published) and suggest that it transcribes the name of its female owner.
Le projet de fouilles à Amathonte de l’Oriental Institute de Chicago (1930)
Authors: Hermary Antoine
Published: October 2016

In 1930 The Oriental institute of Chicago presented to the Cyprus British administration a project of excavation in the acropolis of Amathus. Not prepared enough, this project failed, mainly due to problems with the local owners. In this paper is published the exchange of letters between the British administration and the archaeologists from Chicago.
Chypre au Louvre. Présentation des collections dans les galeries du musée
Authors: Fontan Elisabeth
Published: October 2016

Abstract. The incorporation of the collections from Cyprus into the Département des Antiquités orientales is a typical feature of the Louvre. In the others similar museums they are part of the department of Greek and Roman Antiquities. The first Cypriot pieces acquired from 1851 were displayed in the Musée Assyrien. In 1866 the Amathus vase was installed in the first of the two rooms of this gallery, in the northern wing of the Cour Carrée. As this huge vase is unmovable this gallery remains until now "la salle chypriote".
White Painted V eye-pitchers in Cyprus and the Levant
Authors: Åström Paul
Published: October 2016

Cet article présente des additions inédites ou récemment publiées au corpus des eye-pitchers [cruches à bouche pincée ornée d'un œil] provenant de Chypre, Syrie et Palestine dans l'ouvrage de l'auteur : The Middle Cypriote Bronze Age, paru en 1957. Parmi ces additions figure une cruche inconnue conservée à Glasgow, décorée d'un motif figuratif de serpent. Le prototype de la cruche chypriote est levantin. La forme est inspirée de flacons Syrian Red et Black Burnished. Ils étaient probablement faits à Kalopsidha et exportés de là vers le Levant.
The Royal Tombs of Tamassos. Burial Gifts, Funeral Architecture and Ideology
Authors: Matthäus Hartmut
Published: October 2016

Les tombes 4 et 12 de la «Nécropole Royale» de Tamassos ont conservé une grande partie de leur matériel. La tombe 4 (ca 700 av. J.-C.j -chambre à dromos -contient des restes de chevaux et de char, associés à une armure et des armes. La tombe 12 (vf s.), tombe construite au riche décor architectural, est d'un caractère différent : les offrandes funéraires -armure, armes, récipients en bronze, broches (obeloi) en fer, céramique de table -désignent un riche personnage (aristocrate, voire un roi ?), au statut de guerrier ; le matériel de banquet évoque une cérémonie typique des élites sociales à cette époque. L'auteur tente de définir les changements dans les pratiques funéraires et leur idéologie, en les replaçant dans le cadre plus général de la culture funéraire chypro-archaïque.
3. Cyriote Antiquities from Nicosia-Ayia Paraskevi acquired by the Melbourne Cyprus Expedition in 1955/56
Authors: Merrillees Robert Stuart
Published: October 2016

En étudiant la topographie de ce quartier de Nicosie au début des années 1950,

l’auteur retrace le contexte du site de «Nicosie Ayia Paraskevi » , où ont été alors mises au jour d’importantes tombes de l’Âge du Bronze. Les objets parvenus à Melbourne sont répertoriés et commentés.
5. Légendes de fondation et hellénisation de Chypre. Parcours historiographique
Authors: Fourrier Sabine
Published: October 2016

This article presents a review of studies devoted to the problem of the hellenization

of Cyprus in the Late Bronze Age, which were published since Bérard’s unpublished work about the foundation legends in the fifties.
Recherches récentes au palais d’Amathonte
Authors: Blandin Béatrice , Petit Thierry , Tassignon Isabelle
Published: October 2016

During the four-years campaign 2004-2007, the aim of the excavations in the Palace of Amathus was to establish the E astern and Western limits of the storerooms formerly discovered in the middle of the city acropolis. This goal was reached in 2005 (East) and 2007 (West). Although the Palace had been plundered before destruction, a great amount of objects was found in the thick earth filling which covered the whole area after the destruction of the building (end of 4th century B. C.) : its worth noting many figurines and statuettes, and many attic sherds. During the 2006 campaign a deep sondage was dug in the centre of the area, in order to know more about the first phase of the building (end of 9th c. B. C.). Many sherds from local G eometric pottery were found ; and moreover a handful of sherds from E uboean skyphos (or skyphoi) with pendant concentric semi-circles. They thus represent the oldest A egean pottery of the I ron A ge to be discovered within a settlement.
7th to 5th millennium Eastern Mediterranean: An Introduction to the Identification of Interactions between Cyprus and the North Levant after Pre-Pottery Neolithic Times
Authors: Constantinou Constantinos
Published: October 2016

Cet article se propose d ’ analyser et d ’ expliciter les multiples formes d ’ interaction entre sociétés de l ’ Est du bassin méditerranéen . Il est généralement accepté que l ’ île de Chypre a fait l ’ objet d ’ une vague de migration d ’ agriculteurs venant du continent (vraisemblablement du Sud-Est de l ’ Anatolie et du Levant Nord ) dans la seconde moitié du 9 e millénaire avant J . -C . Ce processus a eu un impact considérable sur le développement humain et social de l ’ île . Étant donné ces interactions précoces , il convient d ’ étudier s ’ il y a eu des contacts entre Chypre et le continent durant les millénaires suivants – de la moitié du 8 e jusqu ’ à la fin du 5 e . Si l ’ existence de tels contacts pouvait être établie , il serait possible d ’ identifier plusieurs types de données : les données tangibles , telles que les produits d ’ échanges et de commerce , ainsi que des idées , les techniques pour fabriquer la poterie , les objets lithiques ou pour construire les bâtiments , l ’ organisation de la maison et de l ’ espace du village . L ’ étude de la nature et du degré de ces interactions nous permettra de voir si les sociétés insulaires et continentales sont restées en contact.
The settlement histories of Cyprus at the opening of the twelfth century BC
Authors: Georgiou Artemis
Published: October 2016

L ’ existence d ’ États politiquement et économiquement puissants de Méditerranée orientale s ’ acheva par une «crise » (fin XIIIe s . -début XIIe s . av . J . -C .) : disparition des sociétés palatiales de l ’ empire hittite et des Mycéniens , graves destructions dans la plupart des États prospères de la côte syro-palestinienne , voire abandon . Entre Égée et Levant , Chypre occupe une place centrale dans ces débats . Son organisation récente en centres urbanisés , suscitée par la demande extérieure de cuivre , lui donne une spécificité dont on examinera la géographie politique (villes côtières contrôlant le commerce du cuivre …), et l ’ impact sur l ’ île de la «crise » : ni dévastateur ni uniforme , il met en évidence une continuité politique et matérielle du Bronze Récent au premier âge du Fer . L ’ objectif de cette étude est de mettre en lumière les diverses réponses régionales des villes chypriotes à la «crise » du XIIe s ., et de reconstituer pour chacune l ’ histoire de son établissement .
À propos de la production céramique chypro- géométrique d’Amathonte
Authors: Georgiadou Anna
Published: October 2016

This article , based on a study of ceramic material from the different contexts attested in Amathous during the Cypro-Geometric period , aims to define and characterize the local pottery production by indicating the regional elements that evidently differentiate it from the contemporary productions of the other regions of the island.
New Evidences for the Definition of Workshops of Cypriote Terracottas at East Aegean Findingspots and its Chronological Background
Authors: Henke Jan-Marc
Published: October 2016

Les terres cuites chypriotes archaïques sont largement attestées dans plusieurs sites de l ’ Égée orientale . À la faveur de nouvelles recherches menées sur les découvertes de l ’ Héraion de Samos et du sanctuaire d ’ Aphrodite à Milet , il est possible de démontrer que la plupart des terres cuites chypriotes découvertes dans cette région de l ’ Égée sont originaires d ’ un nombre réduit d ’ ateliers , situés pour la plupart à proximité de la région de Salamine . Ce qui a été suggéré pour les figurines moulées en plaquette peut maintenant être démontré pour les figurines moulées en creux . Les résultats de cette étude ouvrent une nouvelle perspective sur l ’ apparition des terres cuites chypriotes dans les sanctuaires d ’ Égée orientale , et suscitent de nouvelles questions sur le contexte de ces offrandes .
L’Apollon chypriote, de la nature et des animaux
Authors: Vernet Yannick
Published: October 2016

This paper aims to present the specific personality of the Apollo worshipped in Cyprus , different on several aspects from the classical model of the Greek pantheon . One of these special characteristics concerns the relation of the god with the nature and animals , essential component of the Apollo character . In order to define these specificities , the god Apollo Hylates will be the central element of this reflection . This well-known divinity , linked with the animal kingdom and the cycle of the nature , its worship characteristics and the iconographic representations related to it , had never really been fully studied . In the same way , some other aspects of the Cypriote Apollo will be mentioned like Melanthios or Myrtates , of which the possible link with some plants let us glimpse the curative aspect of the god . Moreover , the cult and / or the iconography of Apollo in Cyprus are very often related to various animals . This relation is expressed through the interactions between the divinity and the bull , the snake or the deer . The different symbolism that are implying their interrelation and their associated imagery will be explored in this study . Based on these results , this paper will conclude in drafting the particular , even unique , character / image and substance of the God Apollo and its worship in the island of Cyprus .
Thrombospondin-1-Derived Peptide RFYVVMWK Improves the Adhesive Phenotype of CD34+ Cells from Atherosclerotic Patients with Type 2 Diabetes
Authors: Cointe Sylvie , Rhéaume Éric , Martel Catherine , Blanc-Brude Olivier , Dubé Evemie , Sabatier Florence , Dignat-George Françoise , Tardif Jean-Claude , Bonnefoy Arnaud
Published: October 2016

CD34+ progenitor cells are growing in use for vascular repair. However, in diabetic individuals with cardiovascular diseases, these cells have dysfunctional engraftment capabilities, which compromise their use for autologous cell therapy. The thrombospondin-1-derived peptide RFYVVMWK has previously been reported to stimulate cell adhesiveness through CD47 and integrin activation pathways. Our aim was to test whether RFYVVMWK preconditioning could modulate CD34+ cell phenotype and enhance its proadhesive properties in diabetic patients. Peripheral blood mononuclear CD34+ cells isolated from 40 atherosclerotic patients with type 2 diabetes (T2D; n = 20) or without (non-T2D; n = 20) were preconditioned with 30 μM RFYVVMWK or truncated peptide RFYVVM. CD34+ cell adhesion was assessed on a vitronectin–collagen matrix and on TNF-α or IL-1β-stimulated HUVEC monolayers. Adhesion receptors, platelet/CD34+ cell conjugates, and cell viability were analyzed by flow cytometry and confocal microscopy. RFYVVMWK increased the adhesion of T2D CD34+ cells by eightfold to the vitronectin–collagen matrix ( p < 0.001) corresponding to a threefold increase compared to unstimulated non-T2D CD34+ cells. The peptide induced the formation of platelet/CD34+ conjugates and increased the expression of TSP-1, CD29, CD51/CD61, and CD62P in both T2D and non-T2D cells. However, RFYVVMWK treatment did not affect the viability/apoptosis of CD34+ progenitor cells. In conclusion, priming CD34+ cells with RFYVVMWK may enhance their vascular engraftment during autologous proangiogenic cell therapy.
Immunomodulatory Effects of Adipose Tissue-Derived Stem Cells on Concanavalin A-Induced Acute Liver Injury in Mice
Authors: Yoshizumi Yasuma , Yukawa Hiroshi , Iwaki Ryoji , Fujinaka Sanae , Kanou Ayano , Kanou Yuki , Yamada Tatsuya , Nakagawa Shingo , Ohara Tomomi , Nakagiri Kenta , Ogihara Yusuke , Tsutsui Yoko , Hayashi Yumi , Ishigami Masatoshi , Baba Yoshinobu , Ishikawa Tetsuya
Published: October 2016

Cell therapy with adipose tissue-derived stem cells (ASCs) is expected to be a candidate for the treatment of fulminant hepatic failure (FHF), which is caused by excessive immune responses. In order to evaluate the therapeutic effects of ASCs on FHF, the in vitro and in vivo immunomodulatory effects of ASCs were examined in detail in the mouse model. The in vitro effects of ASCs were examined by assessing their influence on the proliferation of lymphomononuclear cells (LMCs) stimulated with three kinds of mitogens: phorbol 12-myristate 13-acetate (PMA) plus ionomycin, concanavalin A (ConA), and lipopolysaccharide (LPS). The proliferation of LMCs was efficiently suppressed in a dose-dependent manner by ASCs in the cases of PMA plus ionomycin stimulation and ConA stimulation, but not in the case of LPS stimulation. The in vivo effects of transplanted ASCs were examined in the murine FHF model induced by ConA administration. The ALT levels and histological inflammatory changes in the ConA-administered mice were apparently relieved by the transplantation of ASCs. The analysis of mRNA expression patterns in the livers indicated that the expressions of the cytokines such as Il-6, Il-10, Ifn-γ, and Tnf-α, and the cell surface markers such as Cd3γ, Cd4, Cd8α, Cd11b, and Cd11c were downregulated in the ASC-transplanted mice. The immunomodulatory and therapeutic effects of ASCs were confirmed in the mouse model both in vitro and in vivo. These suggest that the cell therapy with ASCs is beneficial for the treatment of FHF.
Riding with the ants
Authors: Duarte A.P.M. , Attili-Angelis D. , Baron N.C. , Groenewald J.Z. , Crous P.W. , Pagnocca F.C.
Published: October 2016

Isolates of Teratosphaeriaceae have frequently been found in the integument of attine ants, proving to be common and diverse in this microenvironment. The LSU phylogeny of the ant-isolated strains studied revealed that they cluster in two main lineages. The first was associated
with the genus Xenopenidiella whereas the other represented two ant-isolated lineages sister to the taxa Penidiella aggregata and P. drakensbergensis, which are allocated to the new genus Penidiellomyces. The genus Penidiella is limited to the lineage containing
P. columbiana, which is not congeneric with Penidiellomyces or Penidiellopsis, nor with Simplicidiella, a novel genus introduced here to accommodate a strain isolated from ants. For species level analysis, the final 26 aligned sequences of the ITS (498 characters),
cmdA (389 characters), tef1 (342 characters) and tub2 (446 characters) gene regions lead to the introduction of six new species in Xenopenidiella, and one in respectively Penidiellopsis and Simplicidiella. The species described in this study were
distinguished by the combination of morphological and phylogenetic data. Novelties on the integument of leaf-cutting ants from Brazil include: Penidiellopsis ramosus, Xenopenidiella clavata, X. formica, X. inflata, X. laevigata, X. nigrescens,
X. tarda spp. nov., and Simplicidiella nigra gen. & sp. nov. Beta-tubulin is recommended as primary barcode for the distinction of species in Penidiellopsis, whereas ITS was sufficient to distinguish species of Xenopenidiella.
Propaganda interna e endomarketing nas organizações: estudo de caso InBetta
Authors: Castro Priscila Batista de , Gomes Pereira João Antônio
Published: October 2016

O endomarketing tem sido importante para empresas na busca por engajamento junto aos seus colaboradores, assim como sua valorização. A questão-problema deste estudo é: quais as contribuições da campanha de propaganda interna e das ações de endomarketing da InBetta no reposicionamento da marca corporativa? O objetivo geral foi verificar as contribuições da campanha de propaganda interna e das ações de endomarketing da InBetta no reposicionamento da marca corporativa. Concluiu-se que entre as várias contribuições a InBetta conseguiu cumprir seu objetivo, que era a divulgação da nova identidade corporativa.
Development of Toscana sausage with lemon flavor and sodium reduction
Authors: Cardoso Celso De Souza , Quandt-Berlanda Cristiane Vanessa , Stolberg Eder Adriano Cavali , Mücke Naieli , Kalschne Daneysa Lahis , Da Silva-Buzanello Rosana Aparecida , Canan Cristiane
Published: October 2016

The high sodium intake has been related to the increase of non- transmissible chronic diseases, especially hypertension. As in Brazil sodium consumption is still above the recommended, it is necessary to develop food products with low addition. The aim of this study was produce Tuscan sausage with lemon flavor with reduced content of sodium, evaluate the microbiological and physico-chemical quality and sensory acceptance. Three formulations were developed, one control (T1), one with 20% (T2) and one with 30% (T3) of sodium reduction, based on the partial substitution of sodium chloride by PuraQ Arome NA4. Sodium content in formulation T1 was 976 mg /100g, while the formulation T2 was 835 mg/100g and T3 761 mg/100g. The samples produced met the microbiological criteria for research of Salmonella, count of coagulase-positive Staphylococcus, sulfite-reducing Clostridium and Coliforms at 45 °C. The parameters of humidity, lipid, calcium and residual nitrite were in accordance with the legislation for all formulations, but the protein content was attended only by T3 formulation. Hedonic scale test showed no difference between the samples and all were accepted for the sensory attributes color, aroma, texture, flavor and overall acceptance. Acceptability levels were greater than 78.9%, indicating that consumers appreciate the Toscana sausage with lemon flavor, and it is possible to reduce sodium maintaining the sensory quality of the product.
Physical and chemical quality of processed nectar flavors and sold in supermarkets in the city of Cuiabá-MT
Authors: Gobbi Kelly Rodrigues , Almeida Livia Rodrigues , Schirmer Melissa , Faria Rozilaine Aparecida Pelegrine Gomes
Published: October 2016

This study aimed to evaluate the physical and chemical quality of processed passion fruit and peach nectar flavors and sold in supermarkets in the city of Cuiaba-MT. We evaluated the physicochemical parameters total acidity, citric acid, pH, vitamin C content, soluble solids (° Brix) SS/acidity total, reducing and non-reducing and total carbohydrates, as the Institute Adolf Lutz standards. The mean values were subjected to analysis of variance and were submitted to the Scott-Knott test at 5% significance level. The total acidity (g.100g-1) to B and D showed statistically equal averages. However, passion fruit flavor of the brand B showed higher pH value (3.27 ± 0.02a). There was no statistically significant difference in soluble solids / titratable acidity (SS / TA) between the marks for the analyzed flavors. For vitamin C all values were below prescribed by legislation. For total soluble solids the average observed for the passion fruit flavor met the minimum established by legislation. However, for the peach flavor, the marks A and B showed lower values and they were smaller than the minimum values established by legislation. Regarding the parameter non-reducing sugar, the brand presented the biggest non-reducing sugar values for the flavors to analyzed. We concluded that not all analyzed parameters meet the current legislation. Vitamin C and soluble solids were below the established by legislation. There is no standard of identity and quality for non-reducing sugar as sucrose, so important parameter as a criterion of a healthy food.
Mixture design applied to the study of bioethanol production from cheese whey and corn steep liquor
Authors: Farias Fabiane Oliveira , Alberti Aline , Nogueira Alessandro , Demiate Ivo Mottin
Published: October 2016

Apart from creating many positive impacts, the growth of agribusiness has also generates concerns about the production of large amounts of undervalued by-products. Cheese whey and corn steep liquor (from corn flour production, a typical Brazilian food) are among these by-products that can be potential raw materials for obtaining new products such as bioethanol. The objective of this study was to apply an experimental design tool to examine different worts with cheese whey and corn steep liquor for the production of bioethanol. The worts containing 100 % corn steep liquor, and 25 % cheese whey with 75 % corn steep liquor supplemented with glucose were considered the best for the production of bioethanol, with fermentation efficiency reaching around 90 % for both of them. The use of pasteurization and antibiotics was effective in controlling lactic acid production, which results from bacterial contamination. The use of antibiotics showed advantages by reducing the maximum growth rate of yeast, which was reflected in higher rates of fermentation efficiency. The results obtained allowed reaching a high level of ethanol productivity.
Nouvelle donne géopolitique en Seine-Saint-Denis
Authors: Subra Philippe , Serisier Wilfried
Published: October 2016

Aux élections locales de 2014-2015, la droite a, pour la première fois, fait pratiquement jeu égal avec les partis de gauche en Seine-Saint-Denis, un département longtemps emblématique de la « banlieue rouge ». Cette nouvelle étape dans la recomposition du paysage politique et électoral local est le résultat d’évolutions structurelles du territoire et de tendances nationales. Mais elle s’explique aussi par les faiblesses ou, au contraire, l’efficacité des stratégies mises en œuvre par les différents partis : l’incapacité de l’appareil du Parti communiste à s’adapter au nouveau contexte sociologique et à capitaliser sur l’impopularité du gouvernement, les divisions, au sein du PCF, entre orthodoxes et rénovateurs (dont la stratégie de modernisation du territoire n’a guère été plus payante), et, en face, la stratégie de conquête de la droite. La gauche non communiste, menée par Claude Bartolone, a échoué dans sa tentative de s’emparer de nouvelles positions de pouvoir et a connu une véritable déroute.
Le trafic d’armes en Seine-Saint-Denis : aspects géopolitiques et enjeux
Authors: Antoine Jean-Charles
Published: October 2016

Le département de la Seine-Saint-Denis est de plus en plus sous le feu des projecteurs depuis novembre 2015. Vu désormais par une partie de la population française comme un territoire hors de contrôle où les trafics de tous ordres pulluleraient, celui des armes à feu devient emblématique au même titre que dans les quartiers nord de Marseille. Or la comparaison ne peut tenir puisque les deux situations sont différentes dans leurs aspects géographiques, dans l’origine des rivalités internes, dans les pratiques des acteurs mais également dans la représentation que l’État central, proche du 9-3, et qu’une partie des Français se font de ce territoire francilien. Les enjeux sont par conséquent encore plus amplifiés en Seine-Saint-Denis qu’ailleurs en France puisque la proximité de Paris fait planer la menace d’une ceinture criminelle autour de la capitale, qui ferait de ce département une sorte de laboratoire antisystème à même de rogner le monopole étatique de la violence légitime.
L’école en Seine-Saint-Denis : une pauvre école pour des enfants de pauvres ?
Authors: Elie Gatien
Published: October 2016

La question scolaire en Seine-Saint-Denis est chargée de représentations, souvent misérabilistes et spectaculaires. Enseigner et apprendre dans les classes de ce département ne constituent pas pour autant des activités de nature différente. Analyser ce qui se déroule ici permet de comprendre ce qui se joue dans l’école en général. Car, dans ce département, les contradictions de la société française sont exacerbées. Les ressorts de l’échec scolaire s’en trouvent plus facilement identifiables. De la salle de classe à la nation en passant par le quartier, chaque niveau d’observation tend à prouver que la relation entre l’école de la République et les enfants des milieux populaires est problématique, surtout lorsque ces derniers sont issus de l’immigration postcoloniale. Entre les deux, les travailleurs de l’éducation, souvent démunis sur le plan pédagogique et de plus en plus précaires, tentent, tant bien que mal, de résoudre ces contradictions.
Égalité entre hommes et femmes : les mères en première ligne. Un hommage à Camille Lacoste-Dujardin
Authors: Loyer Barbara
Published: October 2016

Cet article souligne l’apport de l’œuvre de Camille Lacoste-Dujardin, directrice de recherche au CNRS, ethnologue spécialiste de la société kabyle, à l’analyse du statut et du rôle des femmes dans les sociétés maghrébines. Son livre Des mères contre les femmes fait apparaître la centralité du rouage féminin au sein du système patriarcal maghrébin où les garantes de la domination masculine sont les mères. Ses recherches dessinent l’image d’un système idéologique et social qui, même lorsqu’il est fragilisé par la modernité, enferme les individus dans des rôles où la liberté individuelle n’a pas de place. Camille Lacoste montre que la société patriarcale, et son corollaire de ségrégation des sexes, est contraire à l’épanouissement individuel des femmes et que l’idéologie islamiste est un vecteur de ce système familial de domination masculine. Les travaux de Camille Lacoste rappellent le rôle crucial des mères dans la transmission à leurs filles des valeurs de soumission ou d’égalité.
Le verbe au sein des manuels à l’école primaire :
Authors: Gourdet Patrice
Published: October 2016

Dans cet article, nous proposons une réflexion diachronique sur les règles définissant le verbe, proposées par des manuels destinés à l’école élémentaire. Au niveau de la langue, le verbe est en effet une notion centrale mais complexe à enseigner. Il est essentiel de mettre en perspective et de combiner différentes dimensions en jeu – sémantique, morphologique, syntaxique – sans les cloisonner ou les réduire à la conjugaison, par exemple. Par une approche comparative modeste, nous tentons de comprendre la nature et l’évolution des propriétés mises en avant depuis un siècle, et l’influence des différents apports linguistiques et didactiques qui ont marqué ces cinquantes dernières années dans les manuels. Le manuel scolaire est en effet un outil particulier à l’articulation entre des programmes officiels et les pratiques des maitres au sein de l’école primaire. C’est un outil chargé d’une valeur institutionnelle, qui « légalise » le savoir enseigné à l’École.
L’ordolibéralisme et la construction européenne
Authors: Dévoluy Michel
Published: October 2016

Né outre-Rhin, l’ordolibéralisme est devenu la pierre angulaire de la construction européenne. L’adhésion à cette doctrine tient, certes, au poids de l’Allemagne et à l’emprise du néolibéralisme. Mais surtout, l’ordolibéralisme offre des règles parfaitement adaptées à la gestion d’une union économique et monétaire rétive à toute intégration politique. Soucieux de préserver leurs souverainetés, les États membres ont ainsi mis en place un fédéralisme tutélaire peu démocratique, axé sur des principes de rigueur et de surveillance multilatérale. En réalité, l’ordolibéralisme originel ne s’arrête pas à l’économie. Il propose aussi une vision du monde dont le contenu social et humaniste interpelle et ouvre des débats sur l’Europe face à son avenir.
Electroencephalogram Neurofeedback: Application in ADHD and Epilepsy
Authors: Mayer Kerstin , Arns Martijn
Published: October 2016

The use of electroencephalogram neurofeedback has been studied in a number of psychiatric disorders, especially for the treatment of attention-deficit/hyperactivity disorder (ADHD). However, many clinicians are not aware of this treatment and the level of evidence supporting its use. In this article, we review the evidence for the efficacy of neurofeedback in several psychiatric disorders and also discuss the specific neurofeedback protocols that have been found effective in the treatment of ADHD, such as slow cortical potential, theta/beta ratio, and sensorimotor rhythm neurofeedback.

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Psychiatr Ann
. 2016;46(10):594–600.]
Evaluating the Evidence for Online Interventions in Mental Health Care
Authors: Ashcroft Katie , Insua-Summerhays Bryony , Schurter Céline
Published: October 2016

This article reviews literature on the evidence for online interventions in treating adults with mental health issues. The authors discuss the benefits and limitations of delivering interventions remotely, as well as evaluate the evidence base for online treatments such as computerized cognitive-behavior therapy and psychoeducation. Some previous reviews about online interventions for mental health needs neglected to include research on remotely delivered family and caregiver interventions; therefore, this article explores that treatment modality. Caregiver interventions examined in this article include online psychoeducation and skills training, which demonstrate promising evidence of improved caregiver coping and knowledge about the patient's illness. Additionally, the authors provide suggestions for future research, such as investigation into the pre and posttreatment psychological well-being of patients to further ascertain the impact of online caregiver interventions.

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Psychiatr Ann
. 2016;46(10):584–588.]
Transdermal Electrical Neurostimulation Therapies in Psychiatry: A Review of the Evidence
Authors: Moehringer Jason , Knable Michael B.
Published: October 2016

Electric current has been used for quite some time in the treatment of mental illness; however, less-invasive user-controlled transcranial electrical neurostimulation (TEN) devices have begun to enter the market. Developers claim significant positive effects across a variety of physical and mental illnesses, as well as more mundane issues of stress and fatigue. However, the field is young and progressing rapidly, and no review of these claims has been conducted to date. This article summarizes the available evidence for user-controlled TEN devices, divided into three domains: efficacy/effectiveness, usability/safety, and mechanics. Limitations in the existing research base are noted and suggestions for future investigation are provided.

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Psychiatr Ann
. 2016;46(10):589–593.]
Application of Hybrid Firefly Algorithm-Tabu Search Technique to Minimize the Makespan in Job Shop Scheduling problem
Authors: Kharat Manoj Govind , Khadke Siddhant Sanjeev , Raut Rakesh D. , Kamble Sachin S. , Kamble Sheetal Jaisingh , Kharat Mukesh Govind
Published: October 2016

The Job shop scheduling problem is an important concern in the manufacturing systems. In this paper, the authors have proposed a hybrid firefly algorithm-tabu search combination technique to solve the Job shop scheduling problems. In the proposed algorithm, a complete scheme of algorithm for Job shop scheduling problems is designed and tabu search algorithm is incorporated with the aim of searching for local optimum of each individual. In order to improve the quality of solutions, in each step of the hybrid algorithms, an effective heuristic is proposed. The proposed heuristic reduces the overtime costs of operations by efficient use of the operation's slack. The performance of the proposed algorithm is tested and evaluated solving well-known benchmarked problems. Finally, the computational results are provided for evaluating the performance and effectiveness of the proposed solution approaches. The results have proved the superiority of proposed approach to other methods such as particle swarm optimization, genetic algorithm in terms of both efficiency and success rate.
Rescheduling Activities in Face of Disruption in House Hold Goods Manufacturing Supply Chain
Authors: Rao K. V.N.V.N. , Janardhana G. Ranga
Published: October 2016

A case study from the household goods manufacturing industry is presented in this paper. The manufacturing system consists of parallel machines to make three varieties of products with different processing time. Order cancel, raw material delay and entry of the returned goods from the after sales service network are considered as disruptive events and delivery performance, average delay and waiting time of the products are selected as performance measures. Hybrid right shift-left shift rescheduling method was applied to evaluate the performance measures. Longest processing time, shortest remaining time and longest remaining time priority rules were followed for sequencing the jobs. The objective of the work is to study the influence of the priority rules and disruption on performance measures. Contribution of this paper is to make the rescheduling activity in the multi-product parallel machine environment under multiple disruptions. These findings will be useful to the industry personnel to handle the disruptions without spoiling the delivery promise.
Ant Colony Optimization for Solving the Container Stacking Problem
Authors: Euchi Jalel , Moussi Riadh , Ndiaye Fatma , Yassine Adnan
Published: October 2016

In this paper, the authors study the Container Stacking Problem (CSP) which is one of the most important problems in marine terminal. An optimization model is developed in order to determine the optimal storage strategy for various container-handling schedules. The objective of the model is to minimize the distance between vessel berthing location and the storage positions of containers. The CSP is solved by an efficient ant colony algorithm based on MAX-MIN ant system variant. The performance of the algorithm proposed is verified by a comparison with ILOG CPLEX for small-sized instances. In addition, numerical results for real-sized instances proved the efficiency of the algorithm.
Designing Information Systems to Facilitate Civil-Military Cooperation in Disaster Management
Authors: Vorraber Wolfgang , Lichtenegger Gerald , Brugger Julia , Gojmerac Ivan , Egly Maria , Panzenböck Katrin , Exner Erik , Aschbacher Helmut , Christian Markus , Voessner Siegfried
Published: October 2016

The efficient management of natural and man-made disasters typically represents a major information exchange and coordination challenge, as in most countries a number of organizations are involved in all phases of the disaster management cycle. In this article, the authors introduce the approach of the Austrian national project INKA, which aims at improving civil-military interoperability between the Austrian Armed Forces and the corresponding federal state level institutions through the introduction of IT-supported information exchange without media discontinuities. Apart from providing a comprehensive overview of their interdisciplinary research methodology, the authors present a number of important results which are based on a detailed qualitative assessment of stakeholder requirements. Furthermore, they provide first insights into designing a valuable IT-platform for civil-military interoperability in Austria.
Optimizing ETL by a Two-Level Data Staging Method
Authors: Liu Xiufeng , Iftikhar Nadeem , Huo Huan , Nielsen Per Sieverts
Published: October 2016

In data warehousing, the data from source systems are populated into a central data warehouse (DW) through extraction, transformation and loading (ETL). The standard ETL approach usually uses sequential jobs to process the data with dependencies, such as dimension and fact data. It is a non-trivial task to process the so-called early-/late-arriving data, which arrive out of order. This paper proposes a two-level data staging area method to optimize ETL. The proposed method is an all-in-one solution that supports processing different types of data from operational systems, including early-/late-arriving data, and fast-/slowly-changing data. The introduced additional staging area decouples loading process from data extraction and transformation, which improves ETL flexibility and minimizes intervention to the data warehouse. This paper evaluates the proposed method empirically, which shows that it is more efficient and less intrusive than the standard ETL method.
Formal Modeling and Analysis of Object Oriented Systems using Triple Graph Grammars
Authors: Chama Wafa , Chaoui Allaoua , Rehab Seidali
Published: October 2016

This paper proposes a Model Driven Engineering automatic translation approach based on the integration of rewriting logic formal specification and UML semi-formal models. This integration is a contribution in formalizing UML models since it lacks for formal semantics. It aims at providing UML with the capabilities of rewriting logic and its Maude language to control and detect incoherencies in their diagrams. Rewriting logic Maude language allows simulation and verification of system's properties using its LTL model-checker. This automatic translation approach is based on meta-modeling and graph transformation since UML diagrams are graphs. More precisely, the authors have proposed five meta-models and three triple graph grammars to perform the translation process. The authors have used Eclipse Generative Modeling tools: Eclipse Modeling Framework (EMF) for meta-modeling, Graphical Modeling Framework (GMF) for generating visual modeling tools and TGG Interpreter for proposing triple graph grammars. The approach is illustrated through an example.