bluuebunny/crossref_metadata_2025 huggingface dataset:
CRABP1 protects the heart from isoproterenol-induced acute and chronic remodeling
Authors: Park Sung Wook , Persaud Shawna D , Ogokeh Stanislas , Meyers Tatyana A , Townsend DeWayne , Wei Li-Na
Published: January 2018

Excessive and/or persistent activation of calcium-calmodulin protein kinase II (CaMKII) is detrimental in acute and chronic cardiac injury. However, intrinsic regulators of CaMKII activity are poorly understood. We find that cellular retinoic acid-binding protein 1 (CRABP1) directly interacts with CaMKII and uncover a functional role for CRABP1 in regulating CaMKII activation. We generatedCrabp1-null mice (CKO) in C57BL/6J background for pathophysiological studies. CKO mice develop hypertrophy as adults, exhibiting significant left ventricular dilation with reduced ejection fraction at the baseline cardiac function. Interestingly, CKO mice have elevated basal CaMKII phosphorylation at T287, and phosphorylation on its substrate phospholamban (PLN) at T17. Acute isoproterenol (ISO) challenge (80 mg/kg two doses in 1 day) causes more severe apoptosis and necrosis in CKO hearts, and treatment with a CaMKII inhibitor KN-93 protects CKO mice from this injury. Chronic (30 mg/kg/day) ISO challenge also significantly increases hypertrophy and fibrosis in CKO mice as compared to WT. In wild-type mice, CRABP1 expression is increased in early stages of ISO challenge and eventually reduces to the basal level. Mechanistically, CRABP1 directly inhibits CaMKII by competing with calmodulin (CaM) for CaMKII interaction. This study demonstrates increased susceptibility of CKO mice to ISO-induced acute and chronic cardiac injury due to, at least in part, elevated CaMKII activity. DeletingCrabp1results in reduced baseline cardiac function and aggravated damage challenged with acute and persistent β-adrenergic stimulation. This is the first report of a physiological role of CRABP1 as an endogenous regulator of CaMKII, which protects the heart from ISO-induced damage.
Sąlygų griežtumas socialinės paramos sistemose: Lietuvos ir kitų Europos Sąjungos šalių palyginimas
Authors: Matulionytė Rimgailė , Navickė Jekaterina
Published: January 2018

Straipsnyje yra siūlomas socialinės paramos sąlygų griežtumo indeksas, leidžiantis išanalizuoti ir palyginti šalių paramos sistemų griežtumą. Indeksui sukurti naudojami MISSOC ir EUROMOD duomenys. Taip pat analizuotas sukurto indekso ir skurdo, socialinės atskirties bei pajamų nelygybės rodiklių ryšys. Rezultatai parodė, kad Lietuvos socialinės paramos sistema pasižymi dideliu griežtumu ES šalių kontekste pagal visas analizuotas dimensijas. Socialinės paramos griežtumui turėjo įtakos ir paskutinioji piniginės socialinės paramos reforma, kurios metu buvo sugriežtintos kai kurios paramos teikimo sąlygos. Taip pat paaiškėjo, kad šalyse, kuriose dominuoja griežtesni paramos trukmės ir dydžio apribojimai, vyrauja didesni skurdo, socialinės atskirties ir pajamų nelygybės rodikliai. Atkreiptinas dėmesys, kad būtent paramos trukmės ir dydžio dimensijoje pagal sąlygų griežtumą pirmauja Lietuva.
The Characteristic Features of Social Dialogue in the Baltics
Authors: Dvorak Jaroslav , Karnite Raita , Guogis Arvydas
Published: January 2018

This article analyzes the characteristic features of social dialogue in the Baltic states. The methodology of the current research is based on an intensive analysis of literature and statistical data. The aim of the present research is to address some gaps that were identified during the literature review. Firstly, why does the social dialogue develop so slowly in the Baltic states? Secondly, what was the role of social partners in that process? We find that the main achievement in social dialogue have been reached by social partners on the national level and, despite the painful austerity measures, the Baltic states showed the benchmark of advanced crisis management.
Gimstamumo, laimės ir lyčių vaidmenų sąsajos
Authors: Galdauskaitė Dovilė
Published: January 2018

Šio straipsnio tikslas – pristatyti naujas gimstamumo teorines prieigas, aiškinančias vaikų susilaukimo, laimės bei lyčių vaidmenų, lyčių (ne)lygybės ir (ne)teisingumo sąsajas, atskleisti šių teorinių prieigų ryšį, aptarti galimybes jas jungti, išryškinant jų perspektyvumą jau išplėtotų teorijų kontekste. Pastarųjų kelių dešimtmečių išsivysčiusių šalių neigiami gimstamumo pokyčiai, pasižymintys gimstamumo mažėjimu ir žemu lygiu, neužtikrinančiu kartų kaitos, nuo XX a. devinto dešimtmečio aiškinti remiantis antrojo demografinio perėjimo (ADP) teorija. Tačiau kai kuriose šalyse jau matomo gimstamumo atsigavimo ADP teorija paaiškinti negali. Kaip atsakas į išplėtotų gimstamumo teorijų trūkumus ir prieštaringus gimstamumo pokyčius šiuo metu plėtojamos dvi naujos, tarpusavyje susijusios teorinės perspektyvos – laimės ir lyčių vaidmenų sąsajos su gimstamumo pokyčiais. Šiuos tris dėmesnis integruojanti analitinė perspektyva papildo R. Lesthaeghe’o ir D. van de Kaa pasiūlytas ADP idėjas. Joje plėtojama bei naujai pritaikoma ir P. McDonaldo pasiūlyta teorinė schema, apimanti kintamas gimstamumo ir lyčių lygybės, lyčių teisingumo sąsajas. Kintamų lyčių vaidmenų modelių ir laimės bei gimstamumo kitimas priklauso nuo platesnio konteksto – darbo ir šeimos vaidmenų derinimo galimybių, susijusių su socialine ir šeimos politika bei darbo rinkos lankstumu, į individą ir šeimą orientuotų institucijų prisitaikymo prie kintamų lyčių vaidmenų. Dėl institucijų neprisitaikymo lyčių vaidmenų modelių kaita, pereinant nuo tradicinio prie egalitarinio lyčių vaidmenų modelio, yra „įstrigusi“ pereinamajame etape, pasireiškiančiame normatyvine sumaištimi, darbo ir šeimos vaidmenų derinimo konfliktu, dėl struktūrinių suvaržymų ribojančiu prokreacinių lūkesčių realizaciją. Pagrindinė dviejų teorijų junginio ir naujas gimstamumo pokyčių aiškinimo galimybes suteikiančios kompleksinės teorinės perspektyvos idėja – žemas gimstamumo ir laimės lygis yra pasikeitusių lyčių vaidmenų preferencijų ir struktūrinių galimybių neatitikimo padarinys, kai institucijos negeba prisitaikyti prie kintamų lyčių vaidmenų.
Socialiai įtraukti ar atskirti? Vyresnio amžiaus žmonių, gyvenančių vienų, patirtys
Authors: Rapolienė Gražina , Mikulionienė Sarmitė , Gedvilaitė-Kordušienė Margarita , Jurkevits Anastasiya
Published: January 2018

Vyresnio amžiaus žmonių socialinės atskirties tyrimuose dominuojanti tendencija – tirti dėsningumus, o šio straipsnio išskirtinumas – siekis atskleisti vyresnio amžiaus žmonių, kurie gyvena vieni, subjektyvius dalyvavimo visuomenėje vertinimus. Socialinė atskirtis / įtrauktis straipsnyje apibrėžiama kaip daugialypė sąvoka, apibūdinanti (ne)teisingus socialinius ryšius. Originalaus empirinio tyrimo (27 pusiau struktūruoti interviu) duomenų analizė atskleidžia platų socialinės atskirties, patiriamos įvairiu lygmeniu, spektrą. Remiantis socialinio teisingumo schema, neįtrauktumo visuomenėje naratyvai grindžiami asmeniniu ir tarpasmeniniu (amžiaus, sveikatos, bendravimo, savarankiškumo), organizaciniu, bendruomenės (darbo) ir visuomenės (dalyvavimo renginiuose ir politikoje) kontekstais.
The burden of non-communicable diseases in relation to economic status of countries
Authors: Pervaiz Ruqiya , Ercantan Özlem
Published: January 2018

Background: The aim of this study was to investigate the correlation between mortality from non-communicable diseases (NCDs) and national human development index (HDI) of a country, as well as investigate the correlation between premature mortality from NCDs and national HDI.

Method: Data for age-standardized mortality rate (ASRM) of NCDs and premature mortality (before age 70 years) in percentage for total NCDs in 2015 were obtained from the World Health Organization (WHO) databases. National HDI data for the year 2015 were obtained from the 2015 Human Development Report. Linear regression model was used for assessment of correlation between HDI and mortality. One-way ANOVA was used to test the difference in mean mortality of various HDI group countries; P ≤ 0.05 was considered significant.

Results: The results suggested an inverse correlation between HDI and ASRM for both men and women. The negative relation was also reported for percentage premature mortality and HDI. Tukey post hoc test (p < 0.001) indicated that countries with very high HDI have low ASRM and premature mortality (compared to those with high HDI and so on). The greatest mortality was observed in low HDI countries.

Conclusion: Management of non-communicable diseases is one of the greatest challenges for low and middle HDI countries. In order to control the disease burden, governments should pay serious attention to their economic development.
Prevalence and gender differences in psychiatric disorders and DSM-IV mental disorders: a population-based study
Authors: Veisani Yousef , Delpisheh Ali , Mohamadian Fathola
Published: January 2018

Background: The early diagnosis of psychiatric disorders is critical as it improves the chance of recovery for patients. The aim of this study was to determine gender disparities in psychiatric and mental disorders in adult persons and to examine the validity of the 28-item General Health Questionnaire (GHQ-28; Persian version) in the diagnosis of patients with suspected psychiatric disorders, along with receiver operating characteristic (ROC) analysis.

Materials and Methods: The cross-sectional study was conducted using cluster random sampling method in three steps. Subjects were screened by GHQ-28 and then evaluated by Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR) for diagnosis/classification of mental disorders. Chi-square test and independent t-test were used for statistical analysis. The ROC curve was used to assess cut-off points.

Results: Of the 763 participants (aged 15 and above), 25.8% of responders demonstrated characteristics of psychological distress; the prevalence in males and females were 20.9% and 29.8%, respectively. The common mental disorders in males were anxiety disorder (18.2%), followed by any major depressive disorder (MDD) (17.4. %), and compulsive disorder (10.0%). In females, the common mental disorders were anxiety disorder (23.6%), followed by any MDD (22.7%), compulsive disorder (13.9%), phobia disorder (10.4%) and psychotic disorder (6.1%). ROC analysis showed that 91.7% of suspected persons had a mental disorder as assessed by DSM-IV-TR.
Experiencias artísticas de personas con dis_capacidad cognitiva: caminos para la estima social
Authors: Otero Caicedo Liliana
Published: January 2018

En esta vivencia investigativa emerge una reflexión creativa, sentida y encarnada en torno a las experiencias de reconocimiento que las personas con dis_capacidad cognitiva de la Fundación Luna Arte viven en sus recorridos artísticos desde la perspectiva de Axel Honneth3. Estas reflexiones nacen desde los cuerpos metaforizados en los body maps que se enmarca desde la investigación basada en las Artes como metodología del estudio. Se concluye principalmente que el disfrute y la participación en la vida artística contribuye a la estima social de esta población y, por ende, al realce de sus capacidades, cualidades y a la valoración de sus aportes dentro de su comunidad.
Esperando a Godot, todavía...
Authors: Rodríguez Zamora José Miguel
Published: January 2018

Este artículo revisa la relación que existe entre la obra de Samuel Beckett, Esperando a Godot, con el contexto filosófico. El llamado teatro del absurdo representa el sentir de una época determinada, pero Beckett consigue traspasar los límites del tiempo para crear una obra de importancia universal con un profundo significado para nuestros días.
Ação fiscalizatória e adequação da indicação, comércio e uso de agrotóxicos por agricultores da fronteira oeste do Rio Grande do Sul
Authors: Ritter Juliano Goulart , Silva Fernando Felisberto da , Russini Alexandre
Published: January 2018

A falta de fiscalização no uso de agrotóxicos junto aos agricultores é fator agravante para o cumprimento da legislação ambiental. O objetivo deste trabalho foi avaliar a validade da ação fiscalizatória no cumprimento da legislação referente ao uso de agrotóxicos por parte dos agricultores da Fronteira Oeste do Rio Grande do Sul e suas consequências à saúde e o ambiente. Foram fiscalizadas 80 propriedades rurais em duas safras agrícolas, antes e após as orientações oficiais da fiscalização estadual. Avaliaram-se os depósitos de agrotóxicos, disponibilidade e uso do EPI, receitas agronômicas, devolução de embalagens vazias e uso de agrotóxicos, conforme as normas e procedimentos legais. As avaliações foram agrupadas em 14 possíveis infrações à legislação de agrotóxicos. Verificou-se um aumento em oito tipos de infrações e em quatro, houve redução. As infrações mais comuns foram a utilização de agrotóxico em desacordo com a receita, o armazenamento irregular, o não fornecimento do EPI, a não destinação correta das embalagens vazias e a não apresentação das receitas agronômicas. A presença da fiscalização auxiliou diretamente na utilização de agrotóxicos em conformidade com a receita.
Avaliação da colmatação após 15 anos de operação de um sistema híbrido de wetland construído
Authors: Favretto Rafael , Giroletti Cristiane Lisboa , Magri Maria Elisa , Suntti Carla
Published: January 2018

O objetivo deste trabalho foi avaliar as condições iniciais de colmatação e o funcionamento de um sistema híbrido de wetland construído (vertical + horizontal), já em operação há 15 anos recebendo esgoto proveniente do Centro de Treinamento de Videira – SC (CETREVI). O período de monitoramento foi de agosto até novembro de 2016. Durante esse período, foram realizadas atividades de limpeza do sistema e de reintrodução das macrófitas, implementando-se uma nova rotina de alimentação do wetland vertical. No efluente, foram analisados os seguintes parâmetros: pH, DQO, SS, N-NH4+, N-NO2-, N-NO3- e P-PO43-. Para a análise de colmatação, foram coletadas amostras do leito do wetland horizontal, as quais foram encaminhadas ao laboratório para secagem, peneiramento e posterior determinação dos sólidos finos e grosseiros. Embora o sistema apresentasse indícios de colmatação, as características físico-químicas do efluente permaneceram dentro dos padrões estabelecidos pela legislação vigente, com exceção apenas dos parâmetros

N-NO2- e N-NO3-. Quanto aos sólidos de colmatação, verificou-se que o primeiro terço do leito apresentou grandes quantidades de sólidos orgânicos, uma ocorrência que pode ser explicada pelo fato de essa parte do leito ser a entrada do efluente no sistema. Já no segundo e terceiro terços do leito essa quantidade diminuiu, mas não de forma acentuada.
Análise de implantação de um sistema de aproveitamento de água pluvial em um empreendimento residencial na cidade de Recife-PE
Authors: Moura Micaella Raíssa Falcão de , Silva Simone Rosa da , Barros Emília Xavier do Rego
Published: January 2018

Os sistemas de aproveitamento de água pluvial (SAAP) para fins não potáveis em edificações representam uma das medidas para reduzir a demanda de água potável e minimizar os problemas relacionados à disponibilidade dos recursos hídricos. O trabalho avaliou a viabilidade técnica e financeira da implantação de um SAAP em um empreendimento residencial- em construção- na Região Metropolitana do Recife por meio de uma simulação, fazendo uso da água da chuva para fins não potáveis na rega de jardins. Para tal, realizou-se um estudo dos índices pluviométricos da região e sua periodicidade, avaliando-se os meses de maior e menor precipitação. O reservatório de armazenamento foi dimensionado por meio do método computacional Netuno e em diferentes cenários de área de captação, de maneira a avaliar a situação ideal para suprir a demanda mensal de água da rega dos jardins. A análise econômica da construção do sistema mostrou que a sua implantação em uma edificação residencial com características similares a utilizada no estudo é tecnicamente e economicamente viável.
Avaliação operacional de trabalhadores durante o uso de motorroçadoras laterais
Authors: Da Silva Guilherme Magro , Gindri Eric Porto , Benetti Bruno Bortoluzzi , Depoi Juliano Dos Santos , Werner Valmir , Brandelero Catize , Ottonelli Jaqueline
Published: January 2018

O presente estudo foi elaborado com base em dados coletados e observações à distância, sem o conhecimento prévio de uma equipe de roçada durante sua jornada de trabalho. Este estudo com objetivo de identificar e avaliar as etapas operacionais na execução da atividade de roçada semimecanizada, utilizando motorroçadoras laterais. A avaliação da equipe ocorreu a partir de observações visuais, além de registros em filmagens para posterior análise e confronto dos tempos e movimentos aferidos. Através das análises evidenciou-se a baixa eficiência de trabalho utilizando motorroçadoras laterais com motor dois tempos (2T). Observou-se um excesso de paradas não operacionais, totalizando 30,6% do tempo total e destes, 59% utilizado para descanso por parte dos operadores. Dessa forma, para melhoria das atividades, faz-se necessário o acompanhamento da operação pelo encarregado, com o intuito de reduzir a improdutividade dos trabalhadores.
Degradação de óleos lubrificantes em motores estacionários movidos a biogas
Authors: Brum Djessica , Rosa Maurício Ferreira da , Lindino Cleber Antonio
Published: January 2018

Com o crescente interesse do uso de biogás como fonte de energia elétrica por meio de motores ciclo Otto, as condições de trabalho destes motores se tornam relevantes para maior eficiência de conversão energética e maior tempo de uso. A utilização correta de óleos lubrificantes permite ampliar a quantidade de horas motor, sem necessidade de troca. Avaliar a qualidade e a degradação dos óleos lubrificantes neste sistema torna-se uma premissa importante, uma vez que o óleo degradado diminui a capacidade de proteção nas peças móveis do motor e aumenta o superaquecimento do sistema. A contaminação por agentes externos eleva a chance do desenvolvimento de borras e aumentando a corrosão de peças. Este trabalho realizou o controle de qualidade de óleos lubrificantes em motores estacionários movidos a biogás. Os óleos foram analisados por espectrofotometria na região do infravermelho, na qual foram verificadas as bandas de oxidação, presença de água, fuligem, nitratos e sulfato, sendo determinada também a acidez total do óleo lubrificante, de acordo com a norma ASTM D4739, preconizada pela Resolução ANP nº 10/2000. O principal problema encontrado foi a quantidade de água presente nos motores, acima do limite de 0,03%, indicando algum problema de vazamento/contaminação no motor. Os testes controlados com diferentes gases apresentaram pouca variação em relação à comparação com ar, ao controle utilizado e ao gás N2, sendo que os principais parâmetros afetados foram a oxidação e a acidez, pois os outros parâmetros não apresentaram diferenças significativas entre si.
Imobilização de concentrado lipolítico de penicillium crustosum em diferentes suportes para aplicação em reações de síntese
Authors: Possebom Gessieli , Possebom Gessica
Published: January 2018

O objetivo deste trabalho foi avaliar a imobilização do concentrado lipolítico bruto e precipitado, obtido a partir do fungo filamentoso Penicillium crustosum em dois suportes, alginato de sódio e argila poço A, e avaliar a atividade enzimática no processo de esterificação. A imobilização dos extratos foi produzida na URI campus de Erechim. O extrato enzimático bruto e precipitado foi imobilizado em alginato de sódio com carvão ativado e montmorrolonita Poço A, conforme metodologias consolidadas e, após, determinou-se a atividade enzimática de síntese para os dois suportes. Em seguida, realizou-se a transesterificação enzimática de óleos vegetais em meio orgânico, a síntese enzimática de etil oleato em sistema livre de solvente, a esterificação enzimática de geraniol e ácido propiônico e a determinação de conversão de transesterificação do óleo de soja. Na etapa de imobilização, o suporte mais eficaz foi o alginato de sódio, tanto para o extrato bruto, quanto para o precipitado. A produção enzimática de ésteres foi mais satisfatória na esterificação de ácido oleico e etanol, apresentando conversão de 64,48% de etil oleato para o extrato bruto imobilizado. Para a reação de transesterificação de óleo vegetal, a maior conversão encontrada foi de 4,68% para o extrato bruto imobilizado. Assim, o suporte mais adequado, nas condições estudadas, foi o alginato de sódio. A produção enzimática de ésteres foi mais satisfatória para o extrato bruto imobilizado, concordando com a maior atividade enzimática, também encontrada nessas condições, apresentando-se, então, de modo geral, como o melhor desempenho encontrado.
THE CONVENTION ON THE RIGHTS OF PERSONS WITH DISABILITIES (CRPD) AND QATAR'S DOMESTIC LEGISLATION: THE POTENTIAL IMPACT ON THE MAIN LEGAL DOMAINS
Authors: RODRÍGUEZ DEL POZO PABLO , BARRANCO AVILÉS MARÍA DEL CARMEN , CUENCA GÓMEZ PATRICIA , AL ALI KHALID , ANSUÁTEGUI ROIG JAVIER , DE ASÍS ROIG RAFAEL
Published: January 2018

Equal rights for persons with disabilities is the ultimate goal mandated by the CRPD, and it can probably be gradually achieved in Qatar as steps are taken towards reconsidering the approach to disability at large. This paper examines what impact the CRPD has on the country’s legislation. To that end, we explore how the sensitive domains –health, education, employment, and justice– need to be re-evaluated in light of the CRPD, where recent improvements in the rights of persons with disabilities in Qatar can enable compliance and where the greater challenges lie. We maintain that although legal reforms are needed for Qatar to comply with CRPD, within existing legislation there is notable potential to accommodate particular amendments that could significantly assist the move towards CRPD compliance. We suggest some structural steps aimed at improving compliance, consisting of the establishment of specific institutions, the promotion of associations that represent persons with disabilities and, above all, advancement of a fundamental shift in the way disability is perceived by society, moving away from the old medical notion of disability with its focus on special features and rehabilitation and instead adopting the social model that mandates inclusion and equality.
THE IMPACT OF ARTICLE 12 OF THE CONVENTION ON THE RIGHTS OF PERSONS WITH DISABILITIES ON QATAR´S PRIVATE LAW
Authors: CUENCA GÓMEZ PATRICIA , BARRANCO AVILÉS MARÍA DEL CARMEN , SERRA MARIA LAURA , ANSUÁTEGUI ROIG JAVIER , RODRÍGUEZ DEL POZO PABLO
Published: January 2018

Article 12 of the Convention on the Rights of Persons with Disabilities provides that persons with disabilities are entitled to full legal capacity on an equal basis with others and obliges State Parties to provide access to the support that they may require exercising this legal capacity. This paper analyzes the main implications of this Article and its impact on Qatar´s legal system, focusing on the general regulation of legal capacity and provisions in the domain of Private Law, including Family Law. We examine how Qatar´s legislation needs to be adapted to the new paradigm of the CRPD, overcoming preconceptions based on the medical model and assistencialism, which is focused on protection, and moving towards the social model and the human rights approach, aimed at promoting the autonomy of persons with disabilities. To comply with Article 12, Qatar must review the legal provisions that allow the deprivation or restriction of legal capacity on the basis of disability and that require “be[ing] of sound of mind” as a condition to perform legal acts or to exercise rights. Qatar must also take action to replace regimes of substituted decision-making with supported decision-making – extending some support mechanisms available in current legislation – and to ensure the respect of the person’s will and preferences.
THE LEGAL RECOGNITION OF THE HUMAN RIGHTS SITUATION OF WOMEN WITH DISABILITIES IN THE STATE OF QATAR
Authors: SERRA MARÍA LAURA , BARRANCO AVILÉS MARÍA DEL CARMEN , CUENCA GÓMEZ PATRICIA , DE ASÍS ROIG RAFAEL , RODRÍGUEZ DEL POZO PABLO
Published: January 2018

From the continental law, this paper analyses the situation regarding the rights and fundamental freedoms of women with disabilities in Qatar. The analysis uses as the main reference, Article 6 of the Convention on the Rights of Persons with Disabilities (CRPD) and the General Comment that the CRPD Committee has made to this article. In this aspect, it tries to outline the difficulties that Qatar, as a State party, has in order to be able and take the very first steps towards a real inclusion for women with disabilities
Drónok szabályzásainak vizsgálata képfeldolgozással
Authors: Dezső Dávid , Sarvajcz Kornél , Husi Géza
Published: January 2018

A kutatás során egy képfeldolgozó szoftvert készítettünk, amelyet drónok repülését kiértékelő vizsgálatok során alkalmazható. Olvasható egy quadkopter szabályozásának bemutatása, a képfeldolgozási technika ismertetése, és a valós körülmények közötti vizsgálat során kapott eredmények.
Classics On The Modern Scene: From A Play To "The United Text Of The Performance" (A.N. Ostrovsky)
Authors:   Sobinov Saratov state conservatory, Zykov Alexei
Published: January 2018

The purpose of this research is to analyze the role of "texts" in staging the plays of the classic repertoire. By “texts” we understand, as it was defined by Y.M. Lotman, the main parts of a performance: the text of the play, the acting text, created by actors and the director, and the “text” of decorations, musical component and the lights design. Our main sources were the performances based on the so-called “playwright’s theater” method when the literary text of the play remains unaltered. We examined such plays as “Crazy money” (2012 Saratov Academic Drama Theater n.a. I.A. Slonov) and "Wolves and sheep" (2015, Tambov State Drama Theater). We have chosen A.N. Ostrovskiy’s plays as his playwriting is gaining its momentum at present. There are several reasons for such popularity: the plays content can be understood by today's viewer; the unity of narratives and the vividness of characters are a good “drama school” for actors and directors; the refined language of plays gets an appetite for literature. We can conclude that the unified “text” is presented in a coherent manner since the "roles" of all elements of the performance are distributed evenly; there, acting becomes the main element. The last but not the least in staging a successful play is the stylistic unity of all performance “texts”. Inventing a performance in such a way the director is able to create an artistic image of the play which - from the written word - will gain truthfulness of what the viewer sees, hears and feels on the scene.
The “Ship Of Fools” And The “Blue Barge”: Popular Constructs, Humanistic Thought And Visuality
Authors:   Taras Shevchenko national University of Kyiv, Kovbasiuk Stephanie
Published: January 2018

In this article, we aim to analyse the peculiarities of the interactions between the text and image taking two compilations as examples – the “Ship of fools” and the “Blue barge”. We will start from the very beginning, when they started taking their shape in the late medieval times until the Renaissance when they underwent some changes. Both compilations had been shaped by H. Teichner and J. van Oestvoren in their poems of the early 15th century. However, the “ship of fools” underwent a considerable transformation in the humanistic culture. In the speech of J. Gall as well as in the eponym poem by S. Brant it turned from the image with a strong moralistic bias into a symbol of universal Folly and madness. Later Erasmus of Rotterdam in his “Praise of Folly” will refine the idea of Folly – Moria – that rules over the world. Illustrations for the “Ship of fools” underlined the universal character of the Folly as far as only jesters and not the ordinary people were depicted on the woodcuts. The “blue barge” did not undergo such a substantial change. It was not included in the “big narratives” of the humanists and thereby remained in the semantic limits of the “bürgermoral”. Nevertheless, it did go beyond the framework of the popular culture. Its way to the “high culture” passed through the artworks by H. Bosch, P. van der Heyden and P. Bruegel the Elder. Painters visualized not just existing carnival practices, but also features of the burger and patrician ethics, which enriched the construct of the “blue barge” and popularized it among different strata of the early modern Netherlandish society.
The Method of Increasing the Cognitive Potential of a Person (R. Feuerstein and R. Guzman)
Authors: Mayzel O.V.
Published: January 2018

The article is devoted to the description and analysis of method of development of intelligence Reuven of Feierstein, a distinguished Israeli scholar and a follower of J. Piaget and L.S. Vygotsky. Based on theoretical experience of his great predecessors R. Feuerstein has developed practical methods to develop cognitive functions in children. A significant role is given to training in adult (mediator), whose tasks include the direction and organization of the learning process by using specially developed techniques. Later, Israeli psychologist R. Guzman has adapted these methods for children suffering from Attention Deficient Hyperactivity Disorder, as well as for born blind people. The exception of the visual perception channel in the proposed set of original methods allows children suffering from Attention Deficient Hyperactivity Disorder, to avoid extra stimulation of brain activity and to focus on completing the tasks given by the mediator. Meanwhile, using the tactile methods when working with born blind people, on the contrary, promotes creating “the library of visual images”. Carrying out consistent lessons based on tactile methodology lead to the behavior correction of the children who suffer from Attention Deficient Hyperactivity Disorder and of born blind people of all age groups, as well as it caused the development of immature or absent cognitive functions.
In the Memory of I.M. Nikolskaya
Authors: Kuftyak E.V.
Published: January 2018

Deep and unhealed soul wound was the news of the death of the doctor of psychological sciences, Professor Irina Mikhailovna Nikolskaya. Light image of Irina Mikhailovna will stay forever in our hearts. It’s impossible to imagine, that with us there is no man, that was light, bright, open, unique and cheerful.
Sense of Composition as Indicator of Artistic Imagination
Authors: Adaskina A.A.
Published: January 2018

The aim of the research presented in this article is to study the role of the sense of composition in the structure of artistic imagination. Based on the analysis of different researches this article interprets the artistic imagination as an independent process aimed at creating an artistic image correlated with the material, anticipating genre, composition and stylistic features. This process includes such aspects as purpose, sense of material and sense of composition. The article presents the data of the first approbation of two methods which diagnose “sense of composition” (“Spot” and “Sheet of paper”). 33 students took part in the approbation (14 of them were students of the art faculty, 19 of them were a control group). As experts in the study participated 3 art сritics. The results of approbation of the methods of diagnostics of compositional thinking ("sense of composition") showed a significant connection between the compositional characteristics of the image and its expressiveness.
Gender Differences in Emotional Intelligence in Adolescence
Authors: Kochetova Y.A. , Klimakova M.V.
Published: January 2018

The article presents the analysis of gender differences in emotional intelligence (EQ) in adolescence. The hypothesis was based on the assumption that there are gender differences in EQ in adolescence. The research involved 111 15-16 years old students, 57 of whom were girls and 54 of whom were boys. An ascertaining experiment with using such measures as "EmIn" (D.V. Lyusin), method of "Assessment of EQ" (N. Hall) and "Diagnosis of gender identity" (S. Bem modificated by V. A. Labunskaya, M. V. Burakova) were taken as a method. As a result, the hypothesis was confirmed, the leading components of EQ for boys and for girls were brought out, the qualitative description of the structure of EQ was given. The research expants the notion of the specifics and gender differences in EQ in adolescence. The obtained data could be used in the age-psychological counseling, in correctional and developmental work with adolescents, and the recommendations for development of EQ could be formulated.
SEKTOR PERDAGANGAN KOTA SURABAYA DI ERA KOMPETISI GLOBAL
Authors: Istifadah Nurul , Wasiaturrahma Wasiaturrahma , Dumauli Magdalena Triasih
Published: January 2018

ABSTRACTThe trade sector provides the biggest contribution of the establishment of gross regional domestic product of Surabaya. The trade sector in Surabaya consists of trade between regions (between districts and between islands) and trade between countries (international trade). The trade contribution between regions is bigger than the international trade. Spacially the trade sector in Surabaya spreads throught districts. There are thirty-one districts in Surabaya. The study aims to analyse the performance of the trade sector in every districts and plan the strategy to improve the performance of the trade sector in Surabaya. An analysis instrument used is shift-share analysis. The research result indicated that the performance of the trade sector ini every district is different.Only six districts have the performance of trade sector are large. It means that the trade sector don’t spread in all districts. Futhermore, based on sectoral and special analysis, the formulations of development strategy of the trade sector in Surabaya are (a) improving access to export both between regents and international trade, (b) enhancing quantity and quality of infrastructurein trade sector, and (c) utilizing the comparative superiority of the trade sector to be the competitive superiority.
PEMAHAMAN DAN KEPATUHAN WAJIB PAJAK ORANG PRIBADI TERHADAP PERATURAN PEMERINTAH NOMOR 46 TAHUN 2013
Authors: Frista Frista , Kristanti Putriana
Published: January 2018

ABSTRACT Understanding and compliance with individual taxpayer to a tax regulations are expected to increase government revenue through taxation. This study aims to determine the level of understanding and compliance of taxpayers to tax obligations in accordance with Peraturan Pemerintah (PP) No. 46 tahun 2013 in terms of the number of final income tax paid each month. The sample in this study is an individual taxpayer who receives income from business with gross turnover which do not exceed Rp .800.000.000,00 within one fiscal year in the Kantor Pelayanan Pajak (KPP) Pratama Yogyakarta. Data processing was performed on 32 samples using Chi-Square test. The results showed that the level of understanding of the majority of  espondents are undecided, and the level of compliance is agreed. There wasno difference in the level of understanding and compliance of taxpayers to tax obligations in accordance with the regulation. The contribution  this study is to provide input to the DJP DIY by showing that most taxpayers do not understand the tax obligations in accordance with PP No. 46 tahun 2013. So that is expected to increase further dissemination and outreach to taxpayers.
Amit Jain’s system of practice for diabetic foot: the new religion in diabetic foot field
Authors: Jain Amit Kumar C.
Published: January 2018

Diabetic foot is a known public health problem and a devastating complication of diabetes that is known to lead to amputation. Past decade has seen various new developments in field of diabetic foot. Amit Jain’s system of practice for diabetic foot is one new such development that was developed for improvising and standardization of diabetic foot. Various new concepts were laid down under this system, thereby creating a separate system that can be equated or considered to be a new religion in diabetic foot field.
Papillary thyroid carcinoma, evaluation of prophylactic central compartment’s dissection versus conservative management: a prospective study
Authors: Ali Ayman M. A. , Abdelhameed Hosam F.
Published: January 2018

Background: Papillary thyroid carcinoma (PTC) is one of the commonest thyroid cancers. While there is consensus of block node dissection in nodal positive patients, there is controversy in dealing with nodal negative patients regarding the need of block node dissection. We aimed to evaluate prophylactic central lymph node dissection (pCLND) versus conservative management in PTC with N0 neck.Methods: This was a prospective randomized study conducted at General Surgery Department, Sohag University Hospital, from August 2013 to September 2017. It included fifty-five patients diagnosed to have PTC with N0 neck randomly divided into two groups; (Group A) included 25 patients who underwent total thyroidectomy (TT) alone and (Group B) included 30 patients who underwent TT with pCLND. We compared both groups regarding the operative and post-operative outcomes.Results: There was temporary hypoparathyroidism with an incidence of 12% for Group A and 23% for Group B (P=0.01). Permanent hypocalcemia occurred in 1 patient in each group (P=0.75). Unilateral recurrent laryngeal nerve (RLN) temporary palsy occurred in 10% for Group B patients and in 8% for Group A patients, (P=0.46). Node metastases were observed in 43% in group B upstaging the disease. Both univariate and multivariate analyses showed that CLN metastasis was significantly associated with age <45, male gender, tumor size >2.0cm, bilaterality, and multifocality. Locoregional recurrence was observed in 4% of patients in group A and in 0% in B.Conclusions: TT+pCLND is a safe treatment in patients with N0 PTC and it can be done without a high complication rate and without recurrence compared to TT without CLND.
Clinical profile of patients with below knee soft tissue injuries
Authors: Sachdev Gurvansh S. , Rajan Manu , Dvivedi Sanjay , Agrawal Saurabh , Rawat Kinnari A. V.
Published: January 2018

Background: In the recent era of trauma majority of people suffer from lower limb injuries, which cause functional disabilities and psychosocial consequences. Lower limb injury specially below knee generally involves young and productive people so it is the prime responsibility of the society to prevent such incidents. Our aim is to study clinical profile of various below knee soft tissue injuries to develop better prediction models for defining the most important target for prevention and to reduce morbidities and disabilities.Methods: The study was conducted in the Department of Surgery, Himalayan Institute of Medical Sciences (HIMS), Swami Ram Nagar, Dehradun, over a period of 12 months. Subjects were recruited from patients presenting in Emergency/Surgery OPD, HIMS, Dehradun with a primary diagnosis of below knee soft tissue injuries. A total of 64 patients were included in the study.Results: Maximum number of patients were in the age group of 20-40 years (46.88%), and were predominantly males (84.38%). The commonest mode of injury was RTA (75%) primarily involving 2 wheelers (72.91%). Most patients (42.18%) had late presentation to the hospital i.e. after 72 hours of injury which was found to be associated with contamination of wound in 66.6% of patients.Conclusions: The study emphasizes the need for preventive strategies and protection mechanisms for lower limb injuries. Late presenting contaminated wounds leads to higher complication rates hence there is need for efficient ambulance services for ensuring timely intervention.
Comparative evaluation of subcutaneous infiltration (port site) vs intraperitoneal infiltration of bupivacaine on post laparoscopic cholecystectomy pain
Authors: Gupta R. S. , Rai A. , Vasuniya Vikram , Choudhary Devendra
Published: January 2018

Background: Laparoscopic cholecystectomy (LC) is now the gold standard technique for the treatment of gallstones disease. Although pain after LC is less intense than after open cholecystectomy, some patients still experience considerable discomfort during early postoperative hours. The aim of this study is to evaluate the effect of intraperitoneal and port site instillation of local anaesthetics on pain relief in early postoperative period following LC.Methods: This is a randomized, prospective analytical study among patients subjected to elective laparoscopic cholecystectomy. Patients were divided into 3 groups as; Group 1 was control, Group 2 was assigned to receive portside infiltration of bupivacaine, while group 3 received combined port site and intraperitoneal instillation of bupivacaine. The evaluation of postoperative pain was done according to the visual analog scale and the dosage of narcotic analgesics consumed and duration of hospital stay was also recorded.Results: At 1st post-operative hour, minimum VAS score was in group 3 (p=0.003). At 4th post-operative hour, Minimum VAS score was in group 3(p=0.015). At 8th post-operative hour, Minimum VAS score was in group 3, (p=0.044). Patients in group 3 received a lower total amount of rescue analgesia and they also had the shortest hospital stay after LC, compared to the patients in the other groups. As regarding the incidence of right shoulder pain, group 3 has minimal no of patients experienced rt shoulder tip pain.Conclusions: Infiltration of bupivacaine into port site and intraperitoneal space is simple, inexpensive and effective technique to minimize early postoperative pain and can be practiced for elective LC.
Clinical, radiological and pathological evaluation of residual disease in women receiving neoadjuvant chemotherapy for locally advance carcinoma breast
Authors: Mishra Mayank , Singh Puspendra , Tripathi Alok
Published: January 2018

Background: Egyptians were first to note this disease, 3,500 years ago and described fairly accurately in George Ebers papyri. This disease occurs almost entirely in women, but men can get it, too. Breast cancer is most common among women worldwide. In India, its second after cancer cervix. Its incidence outranks all other cancers in women >35 years of age. Age adjusted incidence rates vary from 9.7- 28.2/100,000. The treatment of locally advanced breast cancer has considerably changed and now includes a multidisciplinary approach, which is directed both to locoregional control and destruction of distant micro-metastasis. Neoadjuvant therapy causes a reduction in size of primary tumor allowing more conservative surgical approach without any increase in locoregional recurrence rate. Limitations of clinical methods for assessment of response to neoadjuvant chemotherapy have now incorporated by imaging and pathological method.Methods: In present study author assess LABC clinically, radiologically and pathologically by mammography USG, FNAC and histopathologic examination, pre- and post-neoadjuvant chemotherapy and evaluate response to chemotherapy, reduction of tumor volume and prior assessment of the patient’s prognosis.Results: Present study shown USG is more accurate in assessing residual disease in post neoadjuvant chemotherapy in defining the real extent of residual disease and also superior in term of detecting complete pathological response.Conclusions: A multimodal assessment of response of neoadjuvant chemotherapy is needed to direct optimal surgical treatment with acceptable cosmesis.
The frequency of infection in early versus late surgery of compound depressed skull fractures in adults
Authors: Irshad Muhammad , Manzoor Ch Ali , Aamir Muhammad
Published: January 2018

Background: The treatment of penetrating head injuries and depressed skull fracture has shown a gradual change over the past decades. A proper debridement and closure of scalp wounds and dural tears have been shown to decrease infection and mortality rate of compound skull fractures. This study has been designed to determine the frequency of infection in early versus late surgery of compound depressed skull fractures in adults.Methods: A total of 226 (113 in each group) patients with compound depressed skull fracture were taken. Group A was managed by early surgery while group B underwent late surgery. Data were entered and analyzed using computer program SPSS version 18.Results: Out of these 226 study cases, 143(63.3%) were male, while 83 (36.7%) were females. The mean age of study cases was 37.50±10.58. The mean duration of presentation at the hospital was 6.76±2.41 hours. Roadside accident was noted to be a major etiological factor, i.e. 132 (58.4%) presented with the history of roadside accident. Base of the skull was a major site of wound, i.e. 79 (35.0%). The mean size of the wound was 13.79±3.49cm. Wound infection was seen in 51 (22.56%) of present study cases. Wound infection in group A was seen in 11 (9.7%) out of 113 patients while in group B it was 40 (35.4%) out of 113 patients (p=0.000).Conclusions: The findings of the current study have indicated that early surgery among the targeted population is associated with significantly less frequent wound infection.
A randomized control trial to determine the need for postoperative antibiotics after laparoscopic appendicectomy in nonperforated appendicitis
Authors: Kajagar B. M. , Jakiyuddin Rampurwala
Published: January 2018

Background: Acute Appendicitis is the most common cause of acute pain in the abdomen. Appropriate use of prophylactic antibiotics prevents the risk of postoperative surgical site infections (SSIs). However, there is no conclusive guideline concerning the duration of antibiotic usage. A single preoperative prophylactic dose has been recommended by many randomized control trials. Hence, the study aimed to determine the need for postoperative antibiotics after laparoscopic appendicectomy for nonperforated appendicitis.Methods: A total of 100 patients with nonperforated appendicitis undergoing laparoscopic appendicectomy divided into two groups. Group A (n=50) patients received single dose of preoperative antibiotic and group B (n=50) patients received preoperative dose, as well as three postoperative doses of antibiotics. Routine investigations including complete blood count, blood urea, serum creatinine; other investigations such as ultrasound of abdomen were also performed. Following laparoscopic appendicectomy, surgical wound was inspected after 48 h, 72 h, and on day 7 to look for any signs of postoperative SSI.Results: The mean age in group A was 30.74±10.69 years compared to 30.72±9.56 years (p=0.757) in group B. All the patients in study presented with right iliac fossa pain. Three patients in group A (6%) and two patients in group B (4%) had grade III SSIs, which were managed conservatively. The difference between both the groups for incidence of SSIs was statistically insignificant (p=1.000).Conclusions: Prophylactic postoperative doses of antibiotics confer no additional benefit over a single preoperative dose in preventing the postoperative SSIs after laparoscopic appendicectomy.