bluuebunny/crossref_metadata_2025 huggingface dataset:
FİNANS SEKTÖRÜNDE ETKİLİ RİSK YÖNETİMİ İÇİN PERFORMANS DEĞERLENDİRME VE BAŞARISIZLIK TAHMİNİ: BÜTÜNLEŞİK BİR KARAR VERME PROSEDÜRÜ
Authors: SELİM Hasan , Yılmaz BALAMAN Şebnem
Published: April 2017

Gelişmekte olan ülkelerin sosyo-ekonomik statüsünde önemli bir yere sahip olan ve hizmet sektörünün temel bileşenlerinden biri olan finans sektörü bu çalışmanın temel konusunu oluşturmaktadır. Bu çalışmanın temel amaçları; riskli ortamlarda finansal kurumların performansını etkileyecek en önemli faktörlerin belirlenmesi, bu faktörler kullanılarak ekonomik ve finansal performansın değerlendirilmesi ve kurumların gelecekteki başarı/başarısızlık durumlarının üç aşamalı analitik ve karşılaştırmalı bir karar verme yaklaşımı kullanılarak tahmin edilmesidir. Sunulan yaklaşımın uygulanabilirliği Türk bankacılık sektöründe faaliyet gösteren ticari bankaların konu alındığı kapsamlı bir uygulama üzerinde çok sayıda finansal rasyo kullanılarak gösterilecektir.  Bu amaçla, Türk finans sektöründe faaliyet gösteren 44 ticari banka 57 temel finansal rasyo kullanılarak sınıflandırılacaktır. Sunulan yaklaşımın banka yöneticilerine, yatırımcılara, hükümet birimlerine ve derecelendirme kuruluşlarına bankaların finansal performanslarının tahminlenmesi ve riskli sosyo-ekonomik ortamlarda karar verilmesi için kapsamlı bir bakış açısı sunması hedeflenmektedir.
Periodontal profile and radiographic characterization of the jaws in a patient with autosomal dominant osteopetrosis
Authors: da Silva Barbirato Davi , Fogacci Mariana Fampa , Arruda Mariana , Rodrigues Monique Oliveira , Neto Leonardo Vieira
Published: April 2017

Osteopetrosis (OP) comprehends a rare group of conditions, presenting on radiographs increased bone density, deriving from irregularities in osteoclast differentiation or function. In the autosomal dominant osteopetrosis (ADO), some patients stay asymptomatic for some time, or only develop mild symptoms. The dental surgeon is often the first to presuppose the disease during routine imaging examinations, referring the patient to a specialized medical group. Furthermore, osteomyelitis is one of the major OP complications, and should be refrained through frequent dental monitoring. Signals of cortical interruption, sclerotic sequestra or periosteal new bone formation, should be looked for in these patients. Their dental management is complex and procedures encompassing bone tissue, such as implant procedures, tissue regenerations, tooth extractions, maxillofacial surgeries and orthodontic treatments, when elected, should be avoided. This case report describes a case of ADO with a diagnosis of moderate generalized chronic periodontitis, not statistically related to plaque index. This is the first case to describe such a condition, in which the systemic component and the altered bone metabolism seem to be related to the loss of periodontal apparatus, independent of the biofilm. Concerning prevention, we can reinforce the need for frequent dental monitoring to avoid further interventions in those cases.

Learning points:

This paper reports a case in which the systemic component and the altered bone metabolism seem to have been related to the loss of periodontal attachment apparatus, independent of the biofilm.

The periodontal damage observed in the OP patient was not related to the dental plaque, which leads us to suggest that the cases of periodontitis in OP patients should be diagnosed as periodontitis as a manifestation of systemic diseases.

The periodontitis prevention should be longed for in OP patients thus, we propose that doctors responsible for patients with OP refer them to a dental service as soon as possible and that dentists should be aware of the preventive dentistry value as well as the most appropriate dental management for those cases.
Anorexia–cachexia syndrome-like hypothalamic neuroendocrine dysfunction in a patient with a papillary craniopharyngioma
Authors: Balcázar-Hernández Lourdes , Vargas-Ortega Guadalupe , Valverde-García Yelitza , Mendoza-Zubieta Victoria , González-Virla Baldomero
Published: April 2017

The craniopharyngiomas are solid cystic suprasellar tumors that can present extension to adjacent structures, conditioning pituitary and hypothalamic dysfunction. Within hypothalamic neuroendocrine dysfunction, we can find obesity, behavioral changes, disturbed circadian rhythm and sleep irregularities, imbalances in the regulation of body temperature, thirst, heart rate and/or blood pressure and alterations in dietary intake (like anorexia). We present a rare case of anorexia–cachexia syndrome like a manifestation of neuroendocrine dysfunction in a patient with a papillary craniopharyngioma. Anorexia–cachexia syndrome is a complex metabolic process associated with underlying illness and characterized by loss of muscle with or without loss of fat mass and can occur in a number of diseases like cancer neoplasm, non-cancer neoplasm, chronic disease or immunodeficiency states like HIV/AIDS. The role of cytokines and anorexigenic and orexigenic peptides are important in the etiology. The anorexia–cachexia syndrome is a clinical entity rarely described in the literature and it leads to important function limitation, comorbidities and worsening prognosis.

Learning points:

Suprasellar lesions can result in pituitary and hypothalamic dysfunction.

The hypothalamic neuroendocrine dysfunction is commonly related with obesity, behavioral changes, disturbed circadian rhythm and sleep irregularities, but rarely with anorexia–cachexia.

Anorexia–cachexia syndrome is a metabolic process associated with loss of muscle, with or without loss of fat mass, in a patient with neoplasm, chronic disease or immunodeficiency states.

Anorexia–cachexia syndrome results in important function limitation, comorbidities that influence negatively on treatment, progressive clinical deterioration and bad prognosis that can lead the patient to death.

Anorexia–cachexia syndrome should be suspected in patients with emaciation and hypothalamic lesions.
Mechanisms of autophagy induction by sex steroids in bovine mammary epithelial cells
Authors: Zielniok Katarzyna , Sobolewska Agnieszka , Gajewska Małgorzata
Published: April 2017

In dairy cattle, mammary gland involution serves to remodel the secretory tissue and occurs in a period of overlap between mammogenic stimulation caused by the next developing pregnancy and tissue regression induced by milk stasis. At this time, high concentrations of 17β-oestradiol (E2) and progesterone (P4) support the regeneration of the mammary tissue, as well as enhance autophagy, a cellular process induced in response to stressful conditions for energy generation and homeostasis maintenance. This study aimed to elucidate the mechanisms of autophagy induction by E2 and P4 using an in vitro model of involution based on 20-fold reduction of FBS content (from 10% to 0.5%) in the culture medium of BME-UV1 bovine mammary epithelial cells (MECs). Real-time RT-PCR, Western blot and EMSA analyses demonstrated that addition of E2 and P4 caused a genomic effect in BME-UV1 cells, stimulating the expression of autophagy-related genes (ATGs): BECN1, ATG5, LC3B and their corresponding proteins. Furthermore, knockdown of oestrogen receptor (ERα) and experiments with the use of oestrogen and progesterone antagonists (4-hydroxytamoxifen and RU-486, respectively) demonstrated that the observed genomic effect is mediated by steroid receptors. Finally, both steroids were shown to form complexes with beclin1 and regulate Bcl-2 phosphorylation, indicating that an indirect, non-genomic effect of E2 and P4 may also contribute to autophagy induction in bovine MECs.
Hepatic lipid accumulation: cause and consequence of dysregulated glucoregulatory hormones
Authors: Geisler Caroline E , Renquist Benjamin J
Published: April 2017

Fatty liver can be diet, endocrine, drug, virus or genetically induced. Independent of cause, hepatic lipid accumulation promotes systemic metabolic dysfunction. By acting as peroxisome proliferator-activated receptor (PPAR) ligands, hepatic non-esterified fatty acids upregulate expression of gluconeogenic, beta-oxidative, lipogenic and ketogenic genes, promoting hyperglycemia, hyperlipidemia and ketosis. The typical hormonal environment in fatty liver disease consists of hyperinsulinemia, hyperglucagonemia, hypercortisolemia, growth hormone deficiency and elevated sympathetic tone. These endocrine and metabolic changes further encourage hepatic steatosis by regulating adipose tissue lipolysis, liver lipid uptake,de novolipogenesis (DNL), beta-oxidation, ketogenesis and lipid export. Hepatic lipid accumulation may be induced by 4 separate mechanisms: (1) increased hepatic uptake of circulating fatty acids, (2) increased hepaticde novofatty acid synthesis, (3) decreased hepatic beta-oxidation and (4) decreased hepatic lipid export. This review will discuss the hormonal regulation of each mechanism comparing multiple physiological models of hepatic lipid accumulation. Nonalcoholic fatty liver disease (NAFLD) is typified by increased hepatic lipid uptake, synthesis, oxidation and export. Chronic hepatic lipid signaling through PPARgamma results in gene expression changes that allow concurrent activity of DNL and beta-oxidation. The importance of hepatic steatosis in driving systemic metabolic dysfunction is highlighted by the common endocrine and metabolic disturbances across many conditions that result in fatty liver. Understanding the mechanisms underlying the metabolic dysfunction that develops as a consequence of hepatic lipid accumulation is critical to identifying points of intervention in this increasingly prevalent disease state.
PHLPP: a putative cellular target during insulin resistance and type 2 diabetes
Authors: Mathur Alpana , Pandey Vivek Kumar , Kakkar Poonam
Published: April 2017

Progressive research in the past decade converges to the impact of PHLPP in regulating the cellular metabolism through PI3K/AKT inhibition. Aberrations in PKB/AKT signaling coordinates with impaired insulin secretion and insulin resistance, identified during T2D, obesity and cardiovascular disorders which brings in the relevance of PHLPPs in the metabolic paradigm. In this review, we discuss the impact of PHLPP isoforms in insulin signaling and its associated cellular events including mitochondrial dysfunction, DNA damage, autophagy and cell death. The article highlights the plausible molecular targets that share the role during insulin-resistant states, whose understanding can be extended into treatment responses to facilitate targeted drug discovery for T2D and allied metabolic syndromes.
Role of estrogen receptor signaling in skeletal response to leptin in female ob/ob mice
Authors: Turner Russell T , Philbrick Kenneth A , Kuah Amida F , Branscum Adam J , Iwaniec Urszula T
Published: April 2017

Leptin, critical in regulation of energy metabolism, is also important for normal bone growth, maturation and turnover. Compared to wild type (WT) mice, bone mass is lower in leptin-deficientob/obmice. Osteopenia in growingob/obmice is due to decreased bone accrual, and is associated with reduced longitudinal bone growth, impaired cancellous bone maturation and increased marrow adipose tissue (MAT). However, leptin deficiency also results in gonadal dysfunction, disrupting production of gonadal hormones which regulate bone growth and turnover. The present study evaluated the role of increased estrogen in mediating the effects of leptin on bone inob/obmice. Three-month-old femaleob/obmice were randomized into one of the 3 groups: (1)ob/ob + vehicle (veh), (2)ob/ob + leptin (leptin) or (3)ob/ob + leptin and the potent estrogen receptor antagonist ICI 182,780 (leptin + ICI). Age-matched WT mice received vehicle. Leptin (40 µg/mouse, daily) and ICI (10 µg/mouse, 2×/week) were administered by subcutaneous injection for 1 month and bone analyzed by X-ray absorptiometry, microcomputed tomography and static and dynamic histomorphometry. Uterine weight did not differ betweenob/obmice andob/obmice receiving leptin + ICI, indicating that ICI successfully blocked the uterine response to leptin-induced increases in estrogen levels. Compared to leptin-treatedob/obmice,ob/obmice receiving leptin + ICI had lower uterine weight; did not differ in weight loss, MAT or bone formation rate; and had higher longitudinal bone growth rate and cancellous bone volume fraction. We conclude that increased estrogen signaling following leptin treatment is dispensable for the positive actions of leptin on bone and may attenuate leptin-induced bone growth.
Mapping the Synthetic Dosage Lethality Network ofCDK1/CDC28
Authors: Zimmermann Christine , Garcia Ignacio , Omerzu Manja , Chymkowitch Pierre , Zhang Beibei , Enserink Jorrit M
Published: April 2017

Cdk1 (Cdc28 in yeast) is a cyclin-dependent kinase (CDK) essential for cell cycle progression and cell division in normal cells. However, CDK activity also underpins proliferation of tumor cells, making it a relevant study subject. While numerous targets and processes regulated by Cdc28 have been identified, the exact functions of Cdc28 are only partially understood. To further explore the functions of Cdc28, we systematically overexpressed ∼4800 genes in wild-type (WT) cells and in cells with artificially reduced Cdc28 activity. This screen identified 366 genes that, when overexpressed, specifically compromised cell viability under conditions of reduced Cdc28 activity. Consistent with the crucial functions of Cdc28 in cell cycle regulation and chromosome metabolism, most of these genes have functions in the cell cycle, DNA replication, and transcription. However, a substantial number of genes control processes not directly associated with the cell cycle, indicating that Cdc28 may also regulate these processes. Finally, because the dataset was enriched for direct Cdc28 targets, the results from this screen will aid in identifying novel targets and process regulated by Cdc28.
Evaluating Serial Strategies for Preventing Wrong-Patient Orders in the NICU
Authors: Adelman Jason S. , Aschner Judy L. , Schechter Clyde B. , Angert Robert M. , Weiss Jeffrey M. , Rai Amisha , Berger Matthew A. , Reissman Stan H. , Yongue Camille , Chacko Bejoy , Dadlez Nina M. , Applebaum Jo R. , Racine Andrew D. , Southern William N.
Published: April 2017

BACKGROUND:

NICU patients have characteristics believed to increase their risk for wrong-patient errors; however, little is known about the frequency of wrong-patient errors in the NICU or about effective interventions for preventing these errors. We conducted a quality improvement study to evaluate the frequency of wrong-patient orders in the NICU and to assess the effectiveness of an ID reentry intervention and a distinct naming convention (eg, “Wendysgirl”) for reducing these errors, using non-NICU pediatric units as a comparator.

METHODS:

Using a validated measure, we examined the rate of wrong-patient orders in NICU and non-NICU pediatric units during 3 periods: baseline (before implementing interventions), ID reentry intervention (reentry of patient identifiers before placing orders), and combined intervention (addition of a distinct naming convention for newborns).

RESULTS:

We reviewed >850 000 NICU orders and >3.5 million non-NICU pediatric orders during the 7-year study period. At baseline, wrong-patient orders were more frequent in NICU than in non-NICU pediatric units (117.2 vs 74.9 per 100 000 orders, respectively; odds ratio 1.56; 95% confidence interval, 1.34–1.82). The ID reentry intervention reduced the frequency of errors in the NICU to 60.2 per 100 000 (48.7% reduction; P < .001). The combined ID reentry and distinct naming interventions yielded an additional decrease to 45.6 per 100 000 (61.1% reduction from baseline; P < .001).

CONCLUSIONS:

The risk of wrong-patient orders in the NICU was significantly higher than in non-NICU pediatric units. Implementation of a combined ID reentry intervention and distinct naming convention greatly reduced this risk.
Authors: Colorado Gabriel Jaime , Torres-Bejarano Angelica M
Published: April 2017

A case of phoretic association of the pseudoscorpion Cordylochernes scorpioides on the giant harlequin beetle Acrocinus longimanus is reported for the Colombian Amazonia. Despite the harlequin beetle reports for the area, no published records of this association are known for the Amazonia bioregion in Colombia. In March 2016, fifteen pseudoscorpions were collected from the upper abdomen of this beetle species in the municipality of Leticia, Amazonas department, Colombia. The need for reporting and publishing this type of interactions is highlighted.
KELIMPAHAN chaetoceros sp., Rhizosolenia W. DAN Skeletonema sp. DI PERAIRAN PULAU BINTAN
Authors: Syafara Zaitun
Published: April 2017

Pengamatan kelimpahan chaetoceros sp., Rhizosolenia W. DAN Skeletonema sp. telahdilakukan di perairan Pulau Bintan pada bulan Juli 1994 sampai Maret 1995. Pengambilan sampel dilakukan satu bulan sekali.
STATUS TROFIK PERAIRAN WADUK KEDUNGOMBO, JAWA TENGAH, SEBAGN DASAR PENGELOLAAN PERIKANANNYA
Authors: Nastiti Adriani Sri , Kartamihardja Endi Setiadi
Published: April 2017

Pelitian ini bcrtujuan mendapatkan informasi tentang status trofik perairan sebagaidasar teknik pengelolaan perikanan di Waduk Kedungombo. Penelitien dilakukan diempat stasiun yaitu Kemukus, Boyolayer, Wonoharjo dan Nglanji, pada bulan Juli,Septernber den November 1994 Januari den Maret 1995.
KEBUTUHAN OPTIMUM PROTEIN DAN ENERGI PAKAN BENIH IKAN GURAME (Asphronemus gouramy LAc)
Authors: Mokoginta I , Suprayudi M.A , Setiawati M.
Published: April 2017

Penelitian ini dilakukan guna menentukan besarnya kebutuhan protein energi pakan untuk benih ikan gurame (osphronemus gouramy Lac). Dalam penelitian ini digunakan12 macam pakan berkadar protein dan energi berbeda dengen rasio energi protein (C/P) sebesar 6, 8, dan 10 kkal/g protein.
KONTRIBUSI KAUM WANITA DALAM PENGEMBANGAN SISTEM USAHA TANI MINAPADI DI DESA NANGGERANG, BINONG, KABUPATEN SUBANG
Authors: Noor Mohammad , Us Khaidir Ahmady
Published: April 2017

Suatu survei dilakukan untuk mengetehui kontribusi kaum wanita dalampengembangan sistem usaha tani minapadi di Desa Nanggerang, Kecamatan Binong,Kabupeten Subang-Jawa Barat.
PENGGUNAAN SARIBUAH NENAS DAN H2SO4 DALAM PEMISAHAN SERAT TELUR IKAN TERBANG (Cypsilurus spp.)
Authors: Rumahrupute Boetje , Hutuely Luthfie , Pelu Husen
Published: April 2017

Penelitian terhadap penggunaan saribuah nenas dan H2SO4 telah dilakukan untukmemudahkan pemisahan serat telur ikan terbeng (cypsilurus spp.).
PERUBAHAN MIKROBIOLOGI SELAMA PEMBUSUKAN IKAN TEMBANG (Sardinella fimbriata) YANG DIES DAN DISIMPAN PADA SUHU KAMAR
Authors: Indriarti Ninoek , Heruwati Endang Sri
Published: April 2017

Ikan tembang sering kali mendapatkan penangananan yang kurang layak dalam artitidak didinginkan dengan cukup kerena nilai jual yang reclatif rendah, sedangkan biayapendinginan relatif tinggi.
PERCOBAAN PEMELIHARAAN LARVA KEPITING BAKAU, scylla serrata DENGAN JENIS PAKAN ALAMI YANG BERBEDA
Authors: Moria s. Sari Budi , Kasprijo Kasprijo , Yunus Yunus , Rusdi Ibnu
Published: April 2017

Percobaan ini bertujuan untuk mendaprtkan pengaruh jenis pakan alami yangberbeda terhadap pertumbuhan dan kelangsungan hidup larva kepiting bakau selamastadia awal.
Organising the Training Process in Polish Companies Operating on International Markets
Authors: Pauli Urban
Published: April 2017

Training programmes enable employees to develop general and firm-specific competences. In companies that operate on international markets, such programmes also provide the transfer of best practices, routines and procedures between the parent firm and subsidiary. Given the importance of human capital in building sustainable competitive advantage, the training process should be professionally designed and executed. Operating on the domestic market makes it easier to properly design and execute training than it is for companies entering foreign markets. The article presents the results of research that sought to verify the professionalisation of training in 50 Polish companies entering foreign markets. General guidelines for how the process should be executed and the People Capability Maturity Model were used to evaluate the training.
Analiza porównawcza modeli systemów ratownictwa w Polsce i w wybranych krajach
Authors: Kunikowski Grzegorz , Rostek Katarzyna
Published: April 2017

Rescue systems determine safety and guarantee it is provided at an adequate level. One aspect of the development of rescue systems is their continuous improvement and enrichment through the application of specialised tools and methods. Selection of these tools and methods should be preceded by an analysis of currently operating systems both in country and globally. This article presents solutions used outside of Poland which the authors believe could be implemented in Poland’s national rescue system. They base their indication on the analysis of the national rescue systems in Poland and elsewhere.
How healthy are male health sciences students at the Imam Abdulrahman Bin Faisal University?
Authors: Al-Otaibi Sultan T. , Almutahhar Abdullah E. , Aljishi Taha B. , Aljawad Hussain S. , Sebiany Abdulaziz M.
Published: April 2017

This article was migrated. The article was marked as recommended. Objectives: This study aimed to collect information on the personal health status of health sciences students in Imam Abdulrahman Bin Faisal University. It also aimed to investigate the relationships between levels of physical activity and other behaviours as well as specific health indicators in students attending college. Methods: A convenience sample of 147 college students, ages 18 to 24 years, participated in this research study at Imam Abdulrahman Bin Faisal University. The data were obtained through interview questionnaire and trained investigators collected weight, height, blood pressure and blood sugar measurements. Results: Forty-five percent of the students were either overweight or obese (21.8% and 23.1%) while 17.0% of the students were current smokers and 7.5% of them were ex-smokers. The majority of the students (91.8%) had fast food (hamburger, French fries, and soft drink) and out of these 62.9% had it three times or more weekly. Furthermore, 35% or more of the students did not have breakfast or drink milk or have vegetables on a daily basis. Also, 22.4% of the students were inactive. Ten percent of the participants were hypertensive while 1.4% had impaired random blood sugar with increased risk for diabetes mellitus. All of these students were unaware that they had hypertension or high random blood sugar. There was a significant statistical relationship between living in-campus at university and frequency of consumption of fast food (p = 0.003). Conclusion: This study shows that there were high rates of risky lifestyles, namely, obesity, smoking, unhealthy diet, and inactivity among health sciences students, while some have health issues such as hypertension and high risk of diabetes.
Different types of energy piles with heating–cooling cycles
Authors: Wang Cheng-long , Liu Han-long , Kong Gang-qiang , Wang Wai Ng Charles
Published: April 2017

Energy piles are a new kind of foundation that can exchange heat with the surrounding soil. The long term thermal mechanical behavior of energy piles is important to the safety of the structure. Because different heat exchange piles may be used in practice, a comparative analysis under the same heat input is needed. This model test was conducted to assess the effects of cyclic heating and cooling on the thermo-mechanical behavior of semi-floating energy piles. Three types of energy piles with heat exchangers in U-shaped, spiral, W-shaped configurations were subjected to three heating and cooling cycles and a constant working mechanical load in dry sand. Results showed the pile temperature, horizontal earth pressure and thermal strain after heating and cooling cycles nearly recovered to the initial levels. The thermal stress increased gradually after each heating–cooling cycle. With a working load equal to 50 percent of the ultimate capacity, the settlement of each pile accumulated at the end of each cycle. In the end, the settlement of a W-shaped heat exchanger pile was larger than other two piles reaching 0·56% of the pile diameter. The displacement produced in each heating and cooling cycle decreased as the cycle increased.
The water resistance of cement mortars prepared with reverse flotation tailings
Authors: Liu Hui , Wang Wei , Zhao Yunliang , Song Shaoxian
Published: April 2017

Silica mineral tailings from reverse flotation are a cause of great environmental concern. In this work, eco-friendly cement mortars were prepared using reverse flotation tailings (RFT). The experimental results showed that the addition of RFT had no influence on the compressive strength of cement mortars and, according to results of water absorption and contact angles, cement mortars with RFT were more hydrophobic than ordinary cement mortars. The water resistance of mortar can thus be greatly improved through the addition of RFT, and this is attributed to the hydrophobicity of the RFT surfaces. This hydrophobicity can slow down the movement of water molecules in the pores of mortars, resulting in less water content of cement mortars per unit area and per unit time. Better water resistance is beneficial for building materials in humid environments and the preparation of eco-friendly mortars with high water resistance can be achieved by using RFT.
Strength reduction factors for wind and earthquake effects
Authors: Martinez-Vazquez Pedro
Published: April 2017

Strength reduction factors (SRFs) are typically estimated for seismic events ignoring the influence of wind. However, considering that strong earthquakes are commonly followed by a number of moderate to strong aftershocks and that wind is constantly flowing, often with low to medium intensity but occasionally reaching high speeds, then the assumption of using only earthquake ground records to determine SRFs seems questionable. In this paper it is shown that the combined action of strong winds and earthquakes, however low its probability of occurrence, would considerably increase the ductility demand of buildings and cause a decrease in SRFs calculated by ignoring wind. The paper examines the non-linear performance of single-degree-of-freedom systems subject to various levels of winds and earthquake load and deals with the estimation of SRFs associated with those multi-hazard scenarios.
Study on two-phase dynamic behaviours within non-homogeneous debris flow
Authors: Shu Anping , Wang Le , Shao Songdong , Ou Guoqiang
Published: April 2017

Non-homogeneous debris flows consisting of a wide range of grain size are commonly modelled as two-phase flows. In adopting such an approach, a critical grain diameter to separate the solid and liquid phases within such debris flows can be determined through the principles of minimum energy dissipation. In this paper, an improved analytical approach using the resistance formula of water flow and the mass conservation law is presented to determine the velocity of solid and liquid phases within a non-homogeneous debris flow. Some of the dynamic parameters are validated against experimental data measured from the Jiangjia gully. The results show that, for the majority of non-homogeneous debris flows tested, the liquid phase exhibits higher velocity than the solid phase. However, as the bulk density of the debris flow increases, the solid phase tends to have higher velocity than the liquid phase. These findings are shown to have important implications on the vertical grading patterns of bed deposits. The field observations indicate that non-homogeneous debris flows with bulk density being significantly lower, close to and significantly higher than the critical value seem to exhibit, respectively, normal, mixed and inverse grading patterns in the alluvial fan deposits.
A Personalized Model of COQ2 Nephropathy Rescued by the Wild-Type COQ2 Allele or Dietary Coenzyme Q10 Supplementation
Authors: Zhu Jun-yi , Fu Yulong , Richman Adam , Zhao Zhanzheng , Ray Patricio E. , Han Zhe
Published: April 2017

Clinical studies have identified patients with nephrotic syndrome caused by mutations in genes involved in the biosynthesis of coenzyme Q10 (CoQ10), a lipid component of the mitochondrial electron transport chain and an important antioxidant. However, the cellular mechanisms through which these mutations induce podocyte injury remain obscure. Here, we exploited the striking similarities between Drosophila nephrocytes and human podocytes to develop a Drosophila model of these renal diseases, and performed a systematic in vivo analysis assessing the role of CoQ10 pathway genes in renal function. Nephrocyte-specific silencing of Coq2, Coq6, and Coq8, which are genes involved in the CoQ10 pathway that have been associated with genetic nephrotic syndrome in humans, induced dramatic adverse changes in these cells. In particular, silencing of Coq2 led to an abnormal localization of slit diaphragms, collapse of lacunar channels, and more dysmorphic mitochondria. In addition, Coq2-deficient nephrocytes showed elevated levels of autophagy and mitophagy, increased levels of reactive oxygen species, and increased sensitivity to oxidative stress. Dietary supplementation with CoQ10 at least partially rescued these defects. Furthermore, expressing the wild-type human COQ2 gene specifically in nephrocytes rescued the defective protein uptake, but expressing the mutant allele derived from a patient with COQ2 nephropathy did not. We conclude that transgenic Drosophila lines carrying mutations in the CoQ10 pathway genes are clinically relevant models with which to explore the pathogenesis of podocyte injury and could serve as a new platform to test novel therapeutic approaches.
The MicroRNA-199a/214 Cluster Targets E-Cadherin and Claudin-2 and Promotes High Glucose-Induced Peritoneal Fibrosis
Authors: Che Mingwen , Shi Tiantian , Feng Shidong , Li Huan , Zhang Xiaomin , Feng Ning , Lou Weijuan , Dou Jianhua , Tang Guangbo , Huang Chen , Xu Guoshuang , Qian Qi , Sun Shiren , He Lijie , Wang Hanmin
Published: April 2017

Serum response factor (SRF) was found to be involved in the phenotypic transition and fibrosis of the peritoneal membrane during treatment with peritoneal dialysis (PD), but the exact mechanism remains unclear. SRF regulates microRNAs (miRNAs) that contain the SRF-binding consensus (CArG) element in the promoter region. Therefore, we investigated whether the miR-199a/214 gene cluster, which contains a CArG element in its promoter, is directly regulated by SRF. High-glucose (HG) treatment significantly unregulated the expression of the miR-199a-5p/214–3p gene cluster in human peritoneal mesothelial cells (HPMCs). By chromatin immunoprecipitation and reporter assays, we found that SRF binds to the miR-199a-5p/214–3p gene cluster promoter after HG stimulation. In vitro, in HPMCs, silencing of miR-199a-5p or miR-214–3p inhibited the HG-induced phenotypic transition and cell migration but enhanced cell adhesion, whereas ectopic expression of mimic oligonucleotides had the opposite effects. Both miR-199a-5p and miR-214–3p targeted claudin-2 and E-cadherin mRNAs. In a PD rat model, treatment with an SRF inhibitor silenced miR-199a-5p and miR-214–3p and alleviated HG-PD fluid–induced damage and fibrosis. Overall, this study reveals a novel SRF–miR-199a/miR-214–E-cadherin/claudin-2 axis that mediates damage and fibrosis in PD.
The Cyclical Behavior of Unemployment and Wages under Information Frictions
Authors: Morales-Jimenez Camilo
Published: April 2017

I propose a new mechanism for sluggish wages based on workers' noisy information about the state of the economy. Wages do not respond immediately to a positive aggregate shock because workers do not (yet) have enough information to demand higher wages. This increases firms' incentives to post more vacancies, which makes unemployment volatile and sensitive to aggregate shocks. The model is robust to two major criticisms of existing theories of sluggish wages and volatile unemployment: flexibility of wages for new hires and pro-cyclicality of the opportunity cost of employment. Calibrated to U.S. data, the model explains 70% of unemployment volatility.
Effects of Professional and Organizational Identification on Professional-Organizational Conflict and Turnover Intentions among Hotel Chefs
Authors:   The Tourism Sciences Society Of Korea, Lee Kyoung-Ha , Kim Young-Gook
Published: April 2017

This study investigated the effects of professional and organizational identifications on professional-organizational conflict and turnover intentions among hotel chefs. Also, providing an analysis of mediating roles of professional-organizational conflict was another research goal. Data were collected from a survey of 242 hotel chefs and was analyzed using Structural Equation Modeling. The results revealed that professional identifications caused direct effects on prof- essional-organizational conflict, but had no direct effect on turnover intention. Organizational identifications led to direct effects on professional-organizational conflict as well as on turnover int- entions. Professional-organizational conflict influenced turnover intentions. In addition, profess- ional-organizational conflict was a partial mediating factor between the personal-organizational fit and turnover intentions. However, professional-organizational conflict held a perfect mediating role between the professional identifications and turnover intentions. Implications and suggestions for future studies were discussed.
Knowledge, attitude and practice of contraception among the postnatal women in a tertiary care hospital in a rural area in Southern Karnataka, India
Authors: Kripa Sasi , Shetty Hana
Published: April 2017

Background: Contraceptive advice is a component of preventive health care. It is necessary to stabilize the population and to conserve the natural resources for the future generations. An ideal contraceptive should suit an individual’s personal, social, and medical characteristics and requirements. Socio-economic factors and education are few of the factors that play important roles in the acceptance of family planning.Methods: A cross-sectional study regarding knowledge, attitude and practices of family planning was conducted in a tertiary care centre. The postnatal women were interviewed using a pretested, semi structured Performa during a fixed study period. The performa included details like socio demographic features, questions related to knowledge, attitude and practices (KAP) regarding contraceptive use.Results: Results revealed poor good knowledge amongst females, but the knowledge was brought to practice in only 32% females mainly due to lack of knowledge and preference for male babies.Conclusions: Family planning methods including male sterilization should be provided to all the couples and basic quality of education is to be raised.
Knowledge of Computer Ergonomics among Computer Science Engineering and Information Technology Students in Karnataka, India
Authors: Sherif Sirajudeen Mohamed , Saad Mohamed Siddik Shaikhji
Published: April 2017

Ergonomics is the science of designing the job to fit the worker. Neglect of ergonomic principles results in inefficiency and pain in the workplace. The objective of this research is to assess the knowledge of Computer Ergonomics among Computer Science Engineering and Information Technology Students in Karnataka. In this Cross-sectional study, 177 Computer Science Engineering and Information Technology Students were recruited. A questionnaire is used to gather details regarding Personal characteristics, Computer Usage and Knowledge of Ergonomics. Descriptive statistics was produced for Personal characteristics and Computer usage. The distribution of responses to the items related to Ergonomic knowledge was presented by percentage of the subjects who answered correctly. The results shows that Majority of the subjects were unaware of ergonomics (32.8% correct responses), cumulative trauma disorders (18.6% correct responses), healthy postures related to elbow (34.4% correct responses), wrist & hand (39.5% correct responses), Level of Monitor (35% correct responses), Position of mouse (47.4% correct responses) and Mini breaks (42.9% correct responses). This research highlighted the necessity of Ergonomic training regarding healthy postures and the measures to reduce the risk of musculoskeletal disorders for the students.
Risk of Developing Complications among Contact Lens Wearers in Northern Border Region, Saudi Arabia. A Retrospective Cohort Study.
Authors: Hamed Salem Heba , Shahed Alshmary Inaam , Owed Alharby Bashair , Saury Alshmary Iman
Published: April 2017

The present study aims towards investigating the risk of developing complications upon usage of different types of contact lens as well as the role played by different variables related to contact lens usage (replacement time, regular follow-up, etc). This is a retrospective cohort study. The total study sample (n = 143) were recruited from Rafha General Hospital, Northern Border Region, Saudi Arabia. All their data were collected and analyzed using chi square test. A P-Value of <0.05 was considered statistically significant. Reusable contact lens wearers were noted to have significantly more complications than disposable contact lens wearers (P<0.05). The majority of the sample was reported to use contact lens for cosmetic (decorative) purpose than for therapeutic or optical indications (63%). Regular follow-up was significantly associated with decrease incidence of contact lens complications (P<0.01). Handling of reusable contact lenses must be done with care as complications are more likely to occur by using them than daily disposable contact lenses. Moreover, contact lens wearers must be advised about the importance of frequent replacement and regular follow-up as it showed significant decrease in complications. We can conclude from our finding that cosmetic usage of reusable contact lenses without proper handling and cleaning system is not advisable.
A simple and low- cost technique for Closed Incision Negative-Pressure Therapy
Authors: Walczak Dominik Andrzej , Wojtyniak Michał , Trzeciak Piotr Wojciech , Pawełczak Dariusz , Pasieka Zbigniew
Published: April 2017

Surgical site infection (SSI) makes patient care more expensive by prolonging antibiotic usage and hospital stay. Negative pressure wound therapy (NPWT) has been recently reported as a preventive strategy to avoid SSI. We present a simple and low-cost vacuum dressing that may improve surgical wound healing and prevent high-risk wounds from complications.
O perfil e a funcionalidade de idosos inscritos no programa saúde da família
Authors: Drummond Adriano
Published: April 2017

O presente ensaio tem como objetivo fornecer breves informações sobre aspectos do envelhecimento acerca de sua influência sobre a capacidade funcional, não só quanto aos fatores intrínsecos, como as respostas fisiológicas e doenças, mas quanto aos fatores extrínsecos, como a diversidade socioeconômica e demográfica. E ainda dialogar quanto à necessidade de investigação do perfil de idosos inscritos em Programas Saúde da Família, como na região administrativa do Paranoá, Distrito Federal.Palavras chave: gerontologia, envelhecimento, idoso, perfil sócio-demográfico ABSTRACTThis essay aims to provide brief information about aspects of aging on their influence on functional capacity, not only on the intrinsic factors, such as physiological and disease, but as to extrinsic factors such as socioeconomic and demographic diversity. And talk about the need to investigate the profile of seniors enrolled in Family Health Programs, as in the administrative region of Paranoá, Distrito Federal.Keywords: gerontology, aging, elderly, socio-demographic profile RESUMEN Este ensayo tiene como objetivo proporcionar una breve información sobre los aspectos del envejecimiento de su influencia en la capacidad funcional, no sólo en los factores intrínsecos, como fisiológicos y enfermedades, pero en cuanto a factores extrínsecos tales como la diversidad socioeconómica y demográfica. Y si hablamos de la necesidad de investigar el perfil de los adultos mayores inscritos en los programas de salud de la familia, como en la región administrativa de Paranoá, Distrito Federal.Palabras clave: gerontología, el envejecimiento, las personas mayores, perfil sociodemográfico
Efeito de programa para mudança do estilo de vida sobre a percepção de saúde em adultos
Authors: Coelho-Ravagnani Christianne De Faria , Ravagnani Fabrício César De Paula , Ribeiro Tamires Cortat , Da Silva Carlos Henrique Ferreira , Spiri Wilza Carla , Duarte Sebastião Junior Henrique , Burini Roberto Carlos
Published: April 2017

O objetivo do presente estudo foi avaliar a percepção subjetiva dos indivíduos participantes de um programa de MEV de longa duração, com benefícios evidentes na aptidão física, relativos na obesidade e não detectados na alimentação. Dos 104 indivíduos (54, 04 ± 7,7 anos) 74% mulheres que frequentaram o programa com exercícios físicos/aconselhamento alimentar durante 2 anos, realizou-se subamostra aleatória de 24 indivíduos (16 mulheres e 8 homens) com entrevista aberta não-estruturada, contendo uma questão norteadora. Dentro das categorias encontradas, 96% dos entrevistados citaram mudanças relacionadas à dimensão física, 67% nas psicológicas e 83% em dimensão social. Homens e mulheres comportaram-se semelhantemente na sensação de mais saúde, disposição e energia, redução ou manutenção do peso na dimensão física, sentimento de alegria e satisfação na dimensão psicológica e aumento do círculo de amizades dentro da dimensão social. Conclui-se que as melhoras mediante a participação no programa de MEV foi predominantemente relacionada aos aspectos físicos, psicológicos e sociais, podendo serem estes os grandes motivadores da permanência dos indivíduos neste tipo de intervenção preventiva e/ou terapêutica.
Educação e promoção de saúde como estratégia para a reabilitação de pacientes com sequela de AVE
Authors: Mendes Helder Fonseca
Published: April 2017

A educação e promoção de saúde se fazem garantindo conhecimentos, aptidões e oportunidades às pessoas para que elas possam tomar decisões e ter atitudes que melhorem suas condições de saúde.  O treinamento para promoção de saúde de pacientes com seqüelas de AVE (Acidente Vascular Encefálico) e cuidadores de pacientes com sequelas de AVE, pode contribuir para melhorar a qualidade de vida e promover o autocuidado. Métodos: Foram feitos estudos de caso com cinco pacientes e seus respectivos cuidadores. Os pacientes responderam ao Índice Funcional de Barthel e os cuidadores a um questionário de conhecimentos a respeito da patologia e participaram de encontros semanais no Hospital Regional de Planaltina, onde foram respondidas suas dúvidas, receberam treinamento e orientações de acordo com o tema proposto para cada reunião e as principais necessidades dos pacientes. Resultados: Quatro pacientes concluíram o estudo. Observamos que todos tiveram melhora no seu estado funcional. O Índice de Barthel inicial médio foi de 52,5 e o final de 85,0 pontos. Os cuidadores se mostraram dispostos a participar do processo de reabilitação dos pacientes apesar de não terem conhecimentos prévios a respeito da doença. Conclusão: Concluímos que os dados apresentados mostram a relevância da educação e da promoção de saúde como estratégias para a reabilitação de pacientes com seqüela de AVE.
Evaluation of post emergence herbicides on grass weeds in pigeon pea and its bioassay on following crop
Authors: Channabasavanna A.S. , Talwar A.M. , Kitturmath M.S. , Rajakumar. H.
Published: April 2017

A Field experiment was conducted at Agricultural Research Station, Malnoor (UAS, Raichur) during 2012-13 and 2013-14 to study the post emergence herbicides on the control of grassy weeds in pigeon pea and its residual effect on the following pigeon pea. The experiment consists of eight treatments viz, propaquizafop 10 EC @ 0.05, 0.062, 0.10 and 0.125 kg/ha, phenoxaprop-p-ethyl 9.3 % at 0.10 kg/ha and imazethapyr at 0.075 kg /ha applied at 2 to 7 leaf stage of grassy weeds. These treatments were compared with hand weeding twice at 20 and 40 days after sowing and weedy check. The data revealed that Imazethapyr @ 0.075 kg/ha and hand weeding recorded the highest grain yield of 1683 kg/ha and 1521 kg/ha, respectively. The net best treatment was propaquizafop @ 0.062 kg/ha (1372 kg/ha) and further increase in the dose did not had any beneficial effect. These treatments controlled both the monocot weed species, Dinebra retroflexa and Echinochloa colonum very effectively and had no residual effect on the following pigeon pea.
Forecasting of meteorological drought using ARIMA model
Authors: Karthika K. , . Krishnaveni , Thirunavukkarasu V.
Published: April 2017

Drought is a global phenomenon that occurs virtually in all landscapes causing significant damage. Due to the random nature of contributing factors, occurrence and severity of droughts can be treated as stochastic in nature. Early indication of possible drought can help to set out drought mitigation strategies and measures in advance. Therefore drought forecasting plays an important role in the planning and management of water resource systems. The principal objective of the study is to carryout short-term annual forecasting of meteorological drought using Auto Regressive Integrated Moving Average (ARIMA) model in Lower Thirumanimuthar Sub-basin located in semi-arid region of Tamilnadu, India is chosen as the study area which is predominantly affected by drought over few decades. Suitable linear stochastic model, non seasonal autoregressive integrated moving average (ARIMA) was developed to predict drought. The best model was selected based on minimum Akaike Information Criterion (AIC) and Schwarz Bayesian Criterion (SBC). Parameter estimation step indicates that the estimated model parameters are significantly different from zero. The predicted data using the best ARIMA model were compared to the observed data for model validation purpose in which the predicted data show reasonably good agreement with the actual data. Hence the models were applied to forecast drought in the Lower Thirumanimuthar sub-basin region up to 2 years in advance with good accuracy.
Genetic variability and correlation studies in brinjal (Solanum melongena L.)
Authors: Samlind sujin G. , Karuppaiah P. , Saravanan K.
Published: April 2017

The present investigation was carried out in the Department of Horticulture, Faculty of Agriculture, Annamalai University, during the period 2014 - 2015 to asses the extent of genetic variability, heritability, correlation and path coefficient analysis of 60 genotypes of brinjal for yield and shoot and fruit borer tolerance. The experiment was laid out in randomized block design with three replications. The maximum phenotypic and genotypic variation was noted for fruit yield per plant followed by fruit weight, fruit girth, number of fruits per plant and shoot and fruit borer incidence. High heritability along with high estimates of GCV, genetic advance and genetic gain were observed for fruit yield per plant, fruit weight, number of secondary branches per plant and shoot and fruit borer incidence. Among the sixteen morphological characters studied, number of long styled flowers per plant, number of short styled flowers per plant, number of fruits per plant, fruit weight, days to first harvesting and shoot and fruit borer incidence showed positive direct effect. For fruit weight, fruit girth and number of fruits per plant were observed positive and significant correlation. It is suggested that the greater emphasis should be given for selection of these characters.