bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on mesoscopic numerical parameters in numerical tests of sand-pebble geology
Authors: Cheng Xuansheng , Liu Huadong , Liu Haibo , Bu Yuyue , Su Hongling , Chen Chaobo
Published: August 2022

To study the influence of the meso-mechanical parameters of sand-pebble on macro-mechanical properties, the numerical simulation method of discrete-element method and the sand-pebble numerical triaxial tests are used, a test method for elliptical particles is proposed and the sensitivity analysis of the meso-mechanical parameters of sand-pebble is carried out. The results show that the effective modulus of the particles has a significant effect on the macroscopic elastic modulus of the material, and the increase in the macroscopic elastic modulus of the material has an approximately linear relationship with the increase in the effective modulus. The effect of the particle stiffness ratio on the macro-mechanical properties of the material is insignificant. The increase in the friction coefficient is roughly linearly related to the increase in the peak stress. The increase in the interparticle porosity has a negative correlation with the decrease in the peak stress, and the particle diameter ratio affects both the number of particles produced and the peak stress. This paper provides a reference for the theoretical basis for subsequent research on the physical and mechanical characteristics of sand-pebble geology.
Introduction: Festivalisation as a Contested Urban Strategy
Authors: Smith Andrew , Osborn Guy , Quinn Bernadette
Published: August 2022

This chapter introduces the Festivals and the City book, outlining its origins and development during a period dominated by the Coronavirus pandemic. The opening sections provide an overview of the key themes addressed by the book and the various cases and festival/event genres it covers. There is also an introduction to the Chapter structure of the book and the four key sections contained within it. This chapter also introduces some of the key ideas and key issues covered by the book. There is a review of the contemporary use and meaning of the term festival; which provides the basis for an extended discussion about the ways festivals are now incorporated into urban strategies. The core argument – that festivals are now regarded and used a tool to assist municipal authorities with various policy objectives ­– is illustrated through sections which address the value of geographical analyses of urban festivals, the ways festivals have been used in city making, and the related festivalisation of urban spaces. Ultimately, the chapter argues that festivalisation is inevitable in an era where festivals and events have been earmarked as ways of addressing a range of policy objectives from city marketing to social inclusion.
How Music Festival Organisers in Rotterdam Deal with Diversity
Authors: Swartjes Britt , Berkers Pauwke
Published: August 2022

Music festivals have the potential to connect people, foster tolerance and are therefore often perceived as inclusive spaces. At the same time, previous research has shown that festival spaces can be exclusionary spaces, where social inequalities are aggravated. While festivals have dynamics of their own, they are organised on the basis of a specific vision (mission statement) which translates into the programming, staffing, organization and marketing of a festival. Festival organisers play an important role in the creation of festival spaces and the mechanisms of inclusion and exclusion. For positive encounters to occur within festivals and for people to share in the positive atmosphere of the festival, they must be planned and managed. This chapter therefore aims to explore to what extent and how music festival organisers deal with diversity in their everyday practices. We therefore investigate 1) discussing diversity: what meaning do festival organisers attach to the concept of diversity; 2) organising diversity: how they deal with diversity throughout the festival organisation process, and 3) implementing diversity: the difficulties and tensions perceived in making diverse festivals. This chapter is based on a study of ten music festivals in Rotterdam, the Netherlands. This city is often perceived as a festival city and a ‘superdiverse’ city, making it the perfect case to study dynamics of inclusion and exclusion as perceived by music festival organisers.
LINVER: The Linear Version of FRB/US
Authors: Brayton Flint , Reifschneider David
Published: August 2022

FRB/US, a large-scale, nonlinear macroeconomic model of the U.S., has been in use at the Federal Reserve Board for 25 years. For nearly as long, the FRB/US “project” has included a linear version of the model known as LINVER. A key reason that LINVER exists is the vast reduction in the computational costs that linearity confers when running experiments requiring large numbers of simulations under the assumption that expectations are model-consistent (MC). The public has been able to download FRB/US simulation code, documentation, and data from the Federal Reserve Board’s website since 2014. To further expand access to and understanding of the FRB/US project, a package devoted to LINVER is now available on the website. In this paper, we provide both a general introduction to LINVER and an overview of the contents and capabilities of its package. We review the ways that LINVER has been used in past research to study key policy issues; describe the package’s comprehensive set of programs for running simulations with MC expectations, with or without imposing the effective lower bound (ELB) on the federal funds rate and other nonlinear constraints; and illustrate how LINVER deterministic and stochastic simulations can be used to gauge the implications of the ELB for macroeconomic performance and to assess different strategies for mitigating its adverse effects.
Search Frictions, Labor Supply, and the Asymmetric Business Cycle
Authors: Ferraro Domenico , Fiori Giuseppe
Published: August 2022

We develop a business cycle model with search frictions in the labor market and a labor supply decision along the extensive margin that yields cyclical asymmetry between peaks and troughs of the unemployment rate and symmetric fluctuations of the labor force participation rate as in the U.S. data. We calibrate the model and find that cyclical changes in the extent of search frictions are solely responsible for the peak-trough asymmetry. Participation decisions do not generate asymmetry but contribute to the fluctuations in search frictions by changing the size and composition of the pool of job seekers, which in turn affects the tightness ratio and thereby slack in the labor market. The participation rate would be counterfactually asymmetric absent labor supply responses to shocks.
Aceptación familiar de la homosexualidad de los hijos e hijas: la importancia de ver lo que otros no ven
Authors: Flórez Marín Giovanny , Builes Correa María Victoria
Published: August 2022

Objetivo. Identificar los aspectos que favorecen la aceptación familiar de la homosexualidad femenina y masculina de un familiar. Metodología. La investigación fue cualitativa, el método fue hermenéutico. En el estudio participaron cuatro familias del Valle de Aburrá a las cuales se les realizaron dos entrevistas semi- estructuradas. Resultados y conclusión. Se encontraron cuatro categorías: ver lo que no ven los que discriminan, derecho a ser lo que se quiera ser, las educaciones: rutas que van llevando a la aceptación y conocer el gremio homosexual da pie para aceptar. La aceptación que las familias narraron estuvo relacionada con entretejer lo personal de sus hijas e hijos, ver valores y capacidades, reconocer los derechos que tienen; enlazar aspectos sociales como las educaciones e irse preparando para aceptar, además, entrar en relación intersubjetiva con familiares y amigos del “gremio” homosexual como lo nombra una participante para comprender y naturalizar esta realidad.
Aproximación al proceso migratorio de las familias venezolanas al área metropolitana del Valle de Aburrá, Colombia : motivaciones, dinámicas familiares y relaciones de género.
Authors: Restrepo Pineda Jair Eduardo , Castro Rodelo Yeimis Yohana , Bedoya Díaz Hugo Alejandro , López Álvarez Solanyer
Published: August 2022

Objetivo. Realizar una aproximación a las realidades que viven las familias venezolanas en el área metropolitana de Medellín, reconociendo los ajustes tanto individuales como familiares para hacer frente a los cambios originados en sus procesos migratorios, donde las motivaciones migratorias, el género y las dinámicas familiares se convierten en los factores que orientan su inclusión en un nuevo contexto social en Colombia. Metodología. Se desarrolló una investigación cualitativa, con un enfoque hermenéutico-interpretativo, aplicando entrevistas en profundidad. Se realizaron 13 entrevistas a familias venezolanas. Resultados y conclusiones. Se evidenció que la motivación del proceso migratorio está determinada por la precarización de la calidad de vida de estas en su país de origen. Además, al llegar a Colombia las familias generan ajustes en sus dinámicas familiares y en los roles de género, sin embargo, estos son percibidos por los migrantes como cambios coyunturales que no responden necesariamente a transformaciones en las percepciones de quienes han migrado.
Optimizing cut-off grade considering grade estimation uncertainty - A case study of Witwatersrand gold-producing areas
Authors: Birch C.C.
Published: August 2022

Due to grade estimation uncertainty, two statistical errors can occur. The Type I error is where material is classified as ore and mined, despite the true value being below the break-even grade. This material is dilution. The Type II error is where the material is estimated to be below the cut-off grade and is classified as waste, although the true grade is actually above the break-even grade. This material is not mined and is lost. The uncertainty was assumed to follow a normal distribution in a previous study. For this study, estimated block values are compared to those determined after mining (the best estimate of the true grade). This actual data from four mines shows that the uncertainty follows a Laplace distribution. There is no single solution regarding adjusting the cut-off grade away from the break-even grade, considering estimation uncertainty, that could be applied to all gold mines. However, adjusting the cut-off grade downwards (up to 22% for one mine) is noted when optimizing the profit considering grade uncertainties. This type of adjustment could open up significant mining areas and extend the life of the mine.
A review of remote-sensing unmanned aerial vehicles in the mining industry
Authors: Loots M. , Grobbelaar S. , van der Lingen E.
Published: August 2022

The increased adoption of unmanned aerial vehicles (UAVs) may improve the productivity and cost-effectiveness of remote sensing in the mining industry. This review's objective is to enable stakeholders to identify possible application adoption, improvement, and innovation opportunities. The review merges a building block strategy and practical screening criteria to identify possible avenues of research to answer the review questions. After the screening process, 72 documents were included in the review. Papers were classified into four categories: exploration, development, exploitation, and reclamation. Fifteen applications were identified, the majority of which were in the exploration phase. The most often researched applications were topographic surveys, reclamation monitoring, and slope management. From the two UAV types identified, multi-rotor vehicles were the most favoured for all applications. From the eight remote sensing techniques identified, photogrammetry was the one most often used. Other techniques were limited because of complexity, cost, or the incompatibility of sensors and UAVs. The review was limited to published papers in academic journals. Future studies could aim to include empirical data on the latest UAV applications used in the mining industry.
hatbot: comunicación digital y religiosidad tras la pandemia en Latinoamérica
Authors: Wunsch Luana Priscila , Damasceno Silva de Freitas Evelyn , Rafael Nikolay Jonas
Published: August 2022

El aislamiento social que se agravó después de marzo de 2020, por Covid-19, puso en evidencia la necesidad de pensar en una nueva agenda que utilice las tecnologías digitales de la comunicación para apoyar el acortamiento de distancias para tener nuevas posibilidades de interacción. En este sentido, este artículo cualitativo presenta un estudio realizado sobre el uso de chatbots para la continuidad de la comunicaciónentre una comunidad específica: la comunidad religiosa. Este público fue elegido para ejemplificar larelevancia del tema sobre cómo superar, en la actualidad, paradigmas que permitan estar presente comoúnico método interaccional. El diseño metodológico se estructuró en dos fases (i) revisión bibliográficay (ii) aplicación de un cuestionario a participantes ubicados en áreas geográficas de ocho países Brasil,Uruguay, Argentina, Paraguay, Chile, Perú, Bolivia y Ecuador. Los resultados muestran que el uso de los chatbots se dio a través de tecnologías digitales como soporte de pertenencia para una nueva agenda de comunicación y que, en contextos comunitarios, enfatiza la seguridad de “pertenecer” y, a pesar del aislamiento, no estar solo, permitiendo que personas de todos los ámbitos soliciten apoyo en relación con asuntos de actualidad, problemas locales y circunstancias personales. Estas bases destacaron las siguientescategorías de discusión para pensar sobre lo digital en tiempos de crisis humanitaria.
Estereotipos de género en TikTok e Instagram: un experimento de ingeniería inversa para entender los mecanismos de los algoritmos de las redes sociales
Authors: Campos-Pellanda Eduardo , Bueno-Fernandes Anna Cláudia
Published: August 2022

En el contexto de la inmersión de los contenidos digitales durante la pandemia del Covid-19, se hizoevidente la popularización de los mecanismos algorítmicos de curaduría contenidos en la vida cotidiana.Este artículo presenta las observaciones de un experimento de ingeniería inversa realizado en la PUCRS (Brasil) en el que se buscó evidencia del refuerzo (o no) de los estereotipos de género en las redes sociales. Para ello, se crearon cuentas en las aplicaciones TikTok e Instagram, una identificada con pronombresmasculinos y otra con pronombres femeninos. El estudio se dividió en fases en las que se cambiaronlos niveles de interacción con el contenido de las aplicaciones, de manera que fue posible analizar lastransformaciones en los vídeos recomendados para identificar pistas del mecanismo utilizado por laplataforma. Por último, fue posible observar las diferencias entre los contenidos sugeridos para cadaperfil que pueden estar relacionadas con los estereotipos de género y las diferencias de calidad y temaspopulares en cada aplicación. También fue posible percibir qué acciones parecían tener más injerenciaen las recomendaciones y qué tipo de contenido o interacción se priorizaba para cada red. Este estudiono pretende acabar con las discusiones sobre el funcionamiento de las redes sociales, sino aportar nuevas preguntas y reflexiones sobre los parámetros utilizados por su lógica y los posibles efectos positivos ynegativos de estas recomendaciones en diferentes contextos sociales.
Müzik Prova Odalarında Açılı Duvarların Oda Frekans Tepkisi Üzerindeki Etkileri: İzmir Devlet Konservatuvarı ve Işılay Saygın Lisesi Örneği
Authors: DURMAZ Serhat , ZERAFET Atakan
Published: August 2022

Konservatuvarlar ve diğer müzik eğitim kurumlarındaki müzik etüt ve prova odalarının akustik bozulmalara karşı çoğunlukla korumasız şekilde tasarlandığı izlenmektedir. Bu tür odaları akustiği konusunda temel ilkelerin belirlendiği NS-8178 ve ardından ISO 23591:2021 standardı, odanın frekans tepkisindeki bozulmalarını önlemek için mimari form özelliklerinden söz eder: Yumuşak alçak frekans tepkisi veren oda oranlarının seçilmesiyle bas frekanslardaki renklendirme etkilerinin kontrolü, yan duvarlarda yapılan en az 7° açılandırma ile orta frekanslardaki flutter echo (FE) sorunlarının önlenmesi. Açılandırma aynı zamanda orta frekanslarda olduğu gibi alçak frekans ses seviyeleri üzerinde de kısmen etkilidir. Literatürde genel görüş, açılandırmanın renklendirme etkilerini azaltmadığı ancak oda içerisindeki basınç dağılımı üzerinde etkili olduğu yönündedir. Bu çalışmada, hangisinin müzik çalışma odalarının akustiği için daha uygun olduğunu belirlemek adına, aynı oranlara sahip dikdörtgen ve dik yamuk oda modellerindeki frekans tepkileri üzerinde standart sapma değerleri izlenmiştir. Geliştirilen teknikte parametreler, İzmir Devlet Konservatuvarı (İzDK) ve Işılay Saygın Güzel Sanatlar Lisesi (ISGSL) örnek odalarından elde edilen veriler kullanılarak belirlenmiştir. Hacim ve açılandırma ilişkisinin izlenebilmesi amacıyla üç farklı hacim grubu seçilip modellenmiş, Odeon 13’te oda dürtü tepkileri (RIR) üretilmiştir. Aynı oranlara sahip odalardaki açılandırmaların, Schroeder frekansı altındaki değerlerde, aynı modal, temel frekans oluşumları sağladığı izlenmiştir. Schroeder frekansı üzerinde standart sapma değerlerinin hesapları, doğrusal ortalamalı Ayrık Fourier Dönüşümü (DFT) ile MATLAB 2021a yazılım ortamında gerçekleştirilmiştir. Elde edilen verilerden belirli limitler arasındaki sapmalar hesaplanmış, açılandırmadan kaynaklanan frekanslarda yumuşatma etkileri incelenmiştir. Kullanılan istatiksel yöntem, 500 Hz’e kadar olan bölgede %25 yumuşatma etkisinin mümkün olabileceğini göstermiştir.
Secure Exchange of Medical Images Via Extended Visual Cryptography
Authors:   , Olvera-Martinez Luis Angel
Published: August 2022

Medical image security is acquiring its importance to preserve the integrity and confidentiality of information (medical data) from malicious users given its importance in timely and successful diagnosis. In this context, several techniques have been developed to protect medical images, such as encryption, data hiding, image tagging, application of Hash algorithms, etc. This paper proposes a technique to cipher medical images by adding the metadata inside a cover image, based on extended visual cryptography as well as the inclusion of a Hash-like function to verify the integrity of the image and the metadata once they are recovered. The method proposed in this work is implemented using medical images with a grayscale resolution of [0,4095] that is a depth of 12 bits/pixel and color images with 24 bits/pixel depth. Experimental results prove the effectiveness of the proposed method in the task of secure exchange of medical images by allowing higher hiding capability, lower distortion in the visual quality of the image with the hidden medical data, as well as a means to verify the integrity of the sent data, compared to state-of-the-art.
Peptide-MHC Dextramer Assembly v1
Authors: Molvi Zaki
Published: August 2022

This protocol details the assembly of peptide-MHC dextramers for use in downstream applications, including flow cytometric detection or magnetic enrichment of T cells specific for a given peptide-MHC (pMHC). Dextramer assembly of biotinylated pMHC is performed by doping onto a dextran backbone using an economic method described previously. The resulting high valency pMHC dextramers enable profiling of immune responses that may prove difficult to detect using conventional pMHC tetramers.
BICCN_DART-FISH v1
Authors: Chen Chien-Ju
Published: August 2022

This protocol documents DART-FISH procedures used to generate spatial transcriptomic data from human brain section for BICCN.
A Scoping Review of Assessment Tools and Factors Influencing Spoken Language Development Among Pediatric Cochlear Implant Users
Authors: HARITHASAN DEEPASHINI , UMAT CILA
Published: August 2022

The spoken language development strongly depends on the normally functioning auditory system. For children with severe or profound hearing loss, cochlear implant has become the best solution in improving and promoting spoken language, quality of life, self-esteem and social well-being. Standardized self-report questionnaires are considered as the most widely used and low-cost approach to measure spoken language development among children. We aimed to provide an overview of the questionnaires available for assessing the spoken language development among children with cochlear implant. In addition, factors that may influence the development of good spoken language were also reviewed. A literature search from January 2010 to December 2020 making use of the Science Direct and PubMed databases was conducted. Medical Subject Headings (MeSH) and other key words for the search were (communication OR language) AND cochlear implant AND (children OR pediatric) AND (questionnaire OR survey). Research articles that were identified in the database using the keywords were refined by year. Only original articles were selected. Articles that quoted all the selected key words in the title and abstract; and written in English with full text were included in the review. Twelve instruments were utilized in the methodology of the 10 articles. Only one instrument was specific for spoken language assessment of children with cochlear implant. The age at which a child received an implant, good rehabilitation program and active involvement of parents was found to influence development of good spoken language skills among the cochlear implanted children. Cochlear implants provide deaf children with the opportunity to develop spoken language skills. Longer use of a cochlear implant dramatically affects the amount of spoken language. Rather, it was cochlear implantation at a younger age that served to assists spoken language competence. Keywords: Cochlear implant; communication; factors; spoken language; questionnaire; children
Gram-Charlier A Series Based Extended Rule-of-Thumb for Bandwidth Selection in Univariate Kernel Density Estimation
Authors: Dharmani Bhaveshkumar
Published: August 2022

Bandwidth parameter estimation in univariate Kernel Density Estimation has traditionally two approaches. Rule(s)-of-Thumb (ROT) achieve ‘quick and dirty’ estimations with some specific assumption for an unknown density. More accurate solve-the-equation-plug-in (STEPI) rules have almost no direct assumption for the unknown density but demand high computation. This article derives a balancing third approach. Extending an assumption of Gaussianity for the unknown density to be estimated in \textit{normal reference} ROT (NRROT) to near Gaussianity, and then expressing the density using Gram-Charlier A (GCA) series to minimize the asymptotic mean integrated square error, it derives GCA series based Extended ROT (GCAExROT). The performance analysis using the simulated and the real datasets suggests to replace NRROT by a modified GCAExROT rule achieving a balancing performance by accuracy nearer to STEPI rules at computation nearer to NRROT, specifically at small samples.
Analysis of Survival Data by a Weibull-generalized Sibuya Distribution
Authors: Almathkour Fatmah , M. E. Ghitany  , Ramesh C. Gupta  , J. Mazucheli
Published: August 2022

In this paper, we consider a survival model of a series system with random sample size, Z. Such a situation arises in competing risk analysis where the number of causes of failure is random and only the minimum of the survival times due to various causes is observed. Considering the distribution of Z as generalized Sibuya and the baseline distribution as Weibull, a Weibull-generalized Sibuya distribution is derived. The structural properties of the proposed model are studied along with the maximum likelihood estimation of the parameters. Extensive simulation studies are carried out to study the performance of the estimators. For illustration, two real data sets are analyzed and it is shown that the proposed model fits better than some of the existing models.
Assessing SARS-CoV-2 Prevalence in Austria with Sample Surveys in 2020 - A Report
Authors: Kowarik Alexander , Paskvan Matea , Weinauer Marlene , Till Matthias , Schrittwieser Karin , Göllner Tobias
Published: August 2022

Since the beginning of the SARS-CoV-2 pandemic a main metric is the amount of infected people at any given time. We present a valid assessment of the population acutely infected by SARS-CoV-2 in Austria at three distinct points in time: April, May and November 2020. The population of these sample surveys includes people aged 16 or older living in private households.Participants were tested with PCR (polymerase chain reaction) tests using nose-throat swabs. Based on these tests, it is assumed that the number of acute SARS-CoV-2 infections was below 11,000 individuals, or 0.15\% of the target population, in April, below 6,000, in May and below 265,000 in November (i.e. the upper limit of the 95\% confidence interval). In November a comparison with the Austrian Epidemiological Reporting System reveals that more than estimated 50\% of acute infections remain undetected by the official reporting obligations.
Corona: Konzepte für eine verbesserte statistische Datenbasis
Authors: Grossmann Wilfried , Hackl Peter , Richter Josef
Published: August 2022

Die Corona-Statistiken und deren Interpretation stehen im Fokus des öffentlichen Interesses. Die Daten spielen bei Maßnahmen zur Eindämmung der Pandemie eine zentrale Rolle. Betrachtet man den status quo der veröffentlichten Corona-Datenbasis, so klafft zwischen den berechtigten Wünschen und den Notwendigkeiten einer evidenzbasierten Entscheidungsfindung auf der einen Seite und der Wirklichkeit auf der anderen Seite eine bedauerliche Diskrepanz. Es gilt, deutlich verbesserte statistische Grundlagen zur Einschätzung der Situation, zur Information der Bevölkerung und für weiterführende Analysen zu schaffen. Dazu will der Beitrag konkrete Schritte vorschlagen.

Im Abschnitt 2 werden die vorhandenen Daten nach den für die Amtliche Statistik geltenden Qualitätskriterien analysiert. Im Abschnitt 3 wird zuerst ein Konzept zur Erstellung eines {\sl Statistischen Corona Registers} und dann -- als entscheidender Schritt -- ein Konzept zur Einbeziehung von demographischen und sozialstatistischen Daten in das Register entwickelt. Ein solches {\sl Erweitertes Statistisches Corona Register} böte umfassende Analysemöglichkeiten und könnte als Vorstufe für ein Statistisches Data Warehouse für das epidemiologische Geschehen angesehen werden. In Abschnitt 4 werden einige Analysemöglichkeiten mit dem vorgeschlagenen {\sl Erweiterten Statistischen Corona Register aufgezeigt}. Abschnitt 5 diskutiert Fragen des Berichtswesens, Abschnitt 6 fasst die Ergebnisse zusammen.
Factors of Negative Experiences in Children with Respiratory Tuberculosis Who Are on Inpatient Treatment
Authors: Sheloumova O.S. , Zolotova N.V.
Published: August 2022

The aim of the work is to study the differences in the severity of negative experiences associated with certain aspects of the internal picture of the disease in children undergoing inpatient treatment for respiratory tuberculosis (RT) and children with leukemia, as well as in different age groups of children with RT. Sampling and methods. The study data are presented on a sample of patients aged 5 to 13 years (N= 42, 9 boys, 33 girls), divided into subgroups of 5—7 years, 8—11 years and 12—13 years. The technique of “Unfinished Sentences” by V.E. Kagan and I.K. Shatts was used. At the first stage, the level of negative experiences was compared between groups of children with RT, with leukemia and healthy children (using data from the I.K. Schatz study), at the second stage — in different age groups of children with RT. Conclusions. The results showed a higher level of negative experiences in the group of children with RT due to the absence of severe symptoms and, as a result, difficulties in understanding the need to stay in the hospital. The factors of negative experience in children of different age groups were revealed. Conclusions are formulated about the need to take into account age-related features and the specifics of the disease when developing psychological support programs.
Effect of Yoga on Motor Skills and Self-Esteem in Kindergarten Children: A Randomized Controlled Trial
Authors: Jarraya Sana , Jarraya Mohamed , Nouira Saber
Published: August 2022

The present randomized controlled trial examines the effects of yoga, as opposed to general physical education (PE) and passive controls, on the motor skills and self-esteem of Tunisian kindergarten children. Fifty-four children (24 females, 30 males; age 5.2 ± 0.6 years; weight 17.8 ± 2.3 kg; height 103.1 ± 5.0 cm; BMI 17.26 ± 0.46 kg/m2) were randomly divided into three groups of 18 (yoga, PE, and controls), and blindly administered the Eurofit physical fitness test battery and the Rosenberg Self-Esteem Scale prior to and after 12 weeks. During this period, the yoga and PE groups attended two weekly yoga and PE sessions of 30 minutes each, respectively. At T0, no significant differences between the groups were observed (p > 0.660). Repeated-measures analysis of variance associated yoga with higher levels of motor skills (p < 0.05; effect size for arm strength [ηp2] = 0.17, leg strength [ηp2] = 0.17, flexibility [ηp2] = 0.33; speed [ηp2] = 0.61, and balance [ηp2] = 0.19) and global self-esteem in comparison to the PE and control groups (p < 0.001; ηp2 = 0.42). Twelve weeks of kindergarten-based yoga appears to improve self-esteem and motor skills in 5-year-old children. The yoga intervention as a school routine seems to enhance development, health, and the well-being of children.
The dynamics of morphological and functional changes of face neck skin at using injectables
Authors: Khanalieva Isita A.
Published: August 2022

The article deals with the issues of face and neck skin involutional changes, which are considered to be the first and easily determined signs of the body aging. Clinical studies of the effectiveness of the therapy with medicines based on hyaluronic acid, silicon and zinc are presented. Based on the presented data, the possibility of further clinical trials of pharmacological preparations used to treat the skin of the face and neck is discussed.
Of particular interest are data on the dynamics of expression of key biomarkers of skin aging in the combined use of silicon- and zinc-containing injectable drugs. The addition of zinc can enhance the effect of silicon compounds in the composition of these drugs.
Organosilicon (silanol) increases the synthesis of type III collagen and elastin and has a protective effect against photodamage of the skin. An increase in the formation of type III collagen was revealed when using silicon complexes with chitinase, while an increase in the expression of TGF- and an increase in fibroblast proliferation were also revealed.
The use of silicon- and zinc-containing drugs is a promising, but still insufficiently studied direction of therapy for involutional changes in the skin of the face and neck. Silicon and zinc in the composition of drugs for anti-aging therapy can have a synergistic effect, affecting a number of important molecular mechanisms of skin aging.
Basement Fault Activation before Larger Earthquakes in Oklahoma and Kansas
Authors: Park Yongsoo , Beroza Gregory C. , Ellsworth William L.
Published: August 2022

Oklahoma and Kansas experienced unprecedented seismic activity over the past decade due to earthquakes associated with unconventional hydrocarbon development. The modest natural seismicity and incomplete knowledge of the fault network in the region made it difficult to anticipate the locations of earthquakes with larger magnitudes (Mw≥4). Here, we show that monitoring of microearthquakes at regional scale using a pretrained neural phase picker and an earthquake relocation algorithm can illuminate unknown fault structures, and deliver information that can be synthesized for earthquake forecasting. We found that 80% of the larger earthquakes that occurred in the past decade could have been anticipated based on the spatial extent of the seismicity clusters that were formed before these earthquakes occurred. We also found that once a seismicity cluster with a length scale enough to host a larger earthquake was formed, there was a ∼5% chance that it would host one or more larger earthquakes within a year. This probability is nearly an order of magnitude higher than one based on Gutenberg–Richter statistics and preceding seismicity. Applying our approach in practice can provide critical information on seismic hazards for risk management and regulatory decision making.
Magnetic resonance imaging for fistulography in perianal fistula: clinicoradiological correlation
Authors: Sarda Hitesh , Pandey Anshuman , Regmi Sudip , Masood Shakeel
Published: August 2022

Background: This article aims to review the role of magnetic resonance imaging (MRI) fistulography in evaluation of perianal fistula along with its concordance with clinical examination and impact on surgical intervention.Methods: A retrospective study of 61 patients who underwent surgery for anal fistula in RMLIMS collected from database from January 1, 2017 to September, 2021Results: The study showed a significant MRI contribution to clinical evaluation in 65.6%. MRI provided significant information for complex fistu­las than for simple fistulas (45% vs. 14.6%, p=0.01). Proportion of patients with sig­nificant MRI contribution increased with in­creasing Parks grade (grade 1, 8.3%; grade 2, 52.2%, p=0.001). The concordance between St. James Hos­pital grade and Parks classification was 0.768 (Kappa coefficient, p<0.00).Conclusions: Therefore, we propose inclusion of MRI in the preoperative surgical assessment of anal fistulas when recurrent, complex, high grade, or when the external opening is located more than 2 cm from the anal canal.
Incidence of negative appendicectomy: retrospective follow-up of histopathology specimens
Authors: Talreja Deep P. , Bai Rani , Talreja Sagar , Al-Amri Hamed H. , Al Sawafi Khalid , Waseemul Haque Parwez , Albatanony Ayman
Published: August 2022

Background: Diagnosing acute appendicitis (AA) remains challenging in spite of multiple modern diagnostic tools, therefore normal appendices may be removed in some patients thought to have AA. Negative appendectomy remains a concern in current surgical practice. The aim of this study was to determine the rate of negative appendectomy in Ibra hospital in North Sharqiya, Oman.Methods: This is a retrospective analysis of 515 appendectomies carried out at Ibra hospital, North Sharqiya, Oman between January 2019 and December 2021. The final diagnosis was based on histopathology reports which were retrieved.Results: A total of 515 appendectomies were performed during the study period. The mean age of the patients was 22.76 years (range, 10-70 years). Patients older than 12 years represented 81.4% of the study population. Female patients accounted for 47% of all the patients. The negative appendectomy rate (NAR) was 9.7% (50 patients). Out of these 50 negative appendectomies, 24 patients were adult females, 21 were adult males and 5 patients were children (4 female and 1 male). The female sex accounted for 56% of the negative appendectomies.Conclusions: female sex is a risk factor for negative appendicectomy. Most studies have suggested that CT is efficacious only in decreasing the NAR among women; we found that men benefited from CT as well.
Epidemiological review on Gastric cancer
Authors: Kale Rohit Pralhadrao
Published: August 2022

The mortality rate of the patients with gastric cancer is reduced dramatically from past few years. Still the gastric cancer the major concern that is in front of health care professionals and is the second leading cause of cancer death across the world. But the trend of infection and the severity of infection differ as per location and histology. While there has been a marked decline in distal, intestinal type gastric cancers, the incidence of proximal, diffuse gastric carcinoma has been increasing, particularly in the Western countries. The severities of gastric cancer infection also differ by change in geographical location, social and economic status of the respective race as well. The main risk factors for distal gastric cancer include Helicobacter pylori infection and dietary factors; whereas gastro esophageal reflux disease and obesity play important roles in the development of proximal stomach cancer. The main aim of this review is to determine the epidemiology of gastric cancer and to discuss about available strategies for its prevention.
Effect of formulation variables on the characteristics of vildagliptin microspheres
Authors: Mane Sheetal , Vinchurkar Kuldeep , Khan Masheer Ahmed , Sainy Jitendra
Published: August 2022

Vildagliptin, an antihyperglycemic drug, is having high water solubility and shorter elimination half-life. This leads to administer vildagliptin frequently to maintain its therapeutic efficacy. So the Formulation of vildagliptin microspheres might be beneficial in overcoming the side effects of the conventional drug delivery systems during the prolonged treatment.

The aim of the work was to evaluate and fabricate the microspheres, which improved the absorption of drug and increase the release kinetics and also to study the effect of formulation variables.

The microspheres of vildagliptin were formulated by solvent evaporation technique. The formulation variables were the concentration of Ethyl cellulose (EC), Polyvinyl alcohol (PVA), and stirring speed. The resulting microspheres were evaluated for percentage yield, percentage entrapment efficiency, particle size, surface morphology, drug release rates.

The morphological structure of the microspheres revealed spherical shaped structures. Good entrapment were observed. The in vitro drug release was found to be controlled.

Results indicated that physicochemical properties of microspheres strongly affected by the presence of drug/polymer ratios, changing the concentrations of them and effect of variables.
An Education Scholar and a Tightrope Walker: Reflexivity and Self-Discovery through the Research on How African American Women Navigate the Contested Spaces of Predominately White Colleges and Universities
Authors: Haynes Christina S.
Published: August 2022

Chronicling my research on academically successful Black women attending predominately white institutions (PWIs), I reflect upon the anxiety, anger, and disillusionment that I personally experienced in graduate school. I discovered while completing the dissertation that other Black women at PWIs navigate similar challenges. Using narrative inquiry, I explore how this research program developed and how the high-achieving women interviewed shaped my ideas about gender, race, and belongingness and the complexity of coping with racism. I wish for other women of color to realize they are not alone in their frustrations; I hope my research helps these women understand that their presence is both needed and valued in the academy.
Wolfowitz Doctrine marks 30th anniversary
Authors: Bratersky Alexander
Published: August 2022

This year marks the 30th anniversary of the Defense Planning Guidance, which largely shaped the U.S. government’s national security approach at the end of the previous century and the start of the current one. Although it was not adopted as policy, the ideas embodied in it formed the basis of a number of American defense and foreign policy decisions. The plan is also known as the Wolfowitz Doctrine, after its chief architect, neoconservative former US Undersecretary of Defense Paul Wolfowitz. The authors examine key tenets of the strategy, applying them to events of subsequent years. Despite the repudiation of neoconservatism, some aspects of the Defense Planning Guideline persist in American foreign policy conceptions.
Carreiras dos Docentes e dos Técnico-Administrativos em Educação nas Instituições Federais de Ensino: Uma Perspectiva Comparada
Authors: Barros Ana Caroline De Sousa , Souza Irineu Manoel de
Published: August 2022

Este artigo objetiva analisar as semelhanças e diferenças entre as carreiras do Magistério Federal e dos Técnico-Administrativos em Educação (TAE) das Instituições Federais de Ensino. Trata-se de uma pesquisa descritiva de abordagem qualitativa e do tipo bibliográfica e documental. A análise baseia-se no que determina a legislação vigente, incluindo os dispositivos normativos em âmbito nacional sobre gestão de pessoas aplicável a essas Instituições, apresentando a organização do trabalho, a gestão do desenvolvimento e a gestão da compensação das carreiras. Na sistematização dos resultados obtidos, constatou-se que as principais divergências entre as carreiras do magistério federal e dos TAE referem-se ao requisito mínimo, jornada de trabalho semanal, controle de frequência, flexibilidade para alteração da jornada de trabalho, férias, contratação de substituto, requisitos de ingresso, desenvolvimento na carreira, interstício mínimo para progressão, amplitude temporal e possibilidade de afastamento para pós-graduação scricto sensu durante o estágio probatório. A principal contribuição do estudo consiste em apresentar as particularidades das carreiras que compõem o capital humano dessas instituições, permitindo uma reflexão sobre os desafios da área de gestão de pessoas na implantação de políticas e práticas de gestão de recursos humanos para manter os servidores motivados e comprometidos com a organização, apesar das divergências apresentadas na legislação sobre as carreiras analisadas.
Antecedentes do Desempenho Relacional: Comunicação Interorganizacional e Aprendizagem
Authors: Rengel Rodrigo , Manes Koch Amanda , Tramontin Castanha Eduardo , Gasparetto Valdirene
Published: August 2022

O objetivo deste estudo consiste em examinar a influência da comunicação interorganizacional e da aprendizagem no desempenho da relação entre cooperativas agropecuárias e fornecedores. Realizou-se pesquisa de levantamento com boundary spanners de nível corporativo de cooperativas agropecuárias. Um questionário foi enviado via plataforma Google Forms aos 252 boundary spanners que aceitaram o convite e a amostra final totalizou 95 respostas válidas. Para testar as hipóteses da pesquisa, aplicou-se a técnica de Modelagem de Equações Estruturais estimada por meio dos Mínimos Quadrados Parciais. Os resultados evidenciaram que a comunicação interorganizacional influencia positivamente o desempenho da relação. A comunicação interorganizacional também apresentou influência positiva na aprendizagem, que por sua vez, apresentou influência positiva no desempenho da relação. Ademais, a aprendizagem apresentou papel mediador positivo entre a comunicação interorganizacional e o desempenho da relação. Esses resultados elucidam a pertinência de elementos como a comunicação interorganizacional e aprendizagem para os relacionamentos interorganizacionais entre as cooperativas e seus fornecedores.
Sobre la neutralidad epistémica del Argumento del No milagro como Inferencia a la Mejor Explicación
Authors: Remesar Juan Manuel
Published: August 2022

Uno de los argumentos que se han pronunciado en favor del realismo científico es el argumento del no milagro. En este artículo nos propondremos analizar su fuerza haciendo una revisión minuciosa de sus elementos y la conexión entre estos. Para realizar dicha tarea nos valdremos de la reconstrucción del argumento del no milagro como una inferencia a la mejor explicación realizada por Roberto Azar, entre otros, y concluiremos que la estructuración del argumento del no milagro con la forma de una inferencia a la mejor explicación no puede ser utilizada para apoyar el realismo más que el antirrealismo.
Long-Standing Lymphocutaneous Sporotrichosis
Authors: Perez-López Israel , Ruiz-Villaverde Ricardo
Published: August 2022

NONE
Enfermedad por COVID-19 y embarazo
Authors: Espitia De La Hoz Franklin José
Published: August 2022

La presencia de COVID-19 en una mujer embarazada plantea una serie de inquietantes preocupaciones, ya que otros tipos de coronavirus se han asociado con resultados adversos. El objetivo de este artículo es realizar una búsqueda bibliográfica acerca del abordaje apropiado para pacientes embarazadas con COVID-19. Se realizó una búsqueda sistemática en las bases de datos: embase (Elsevier), Lilacs (Biblioteca Virtual en Salud-bvs, interfaz iAHx), Medline (PubMed), Science Direct, Cochrane Database of Systematic Reviews (Wiley), dare (Database of Abstracts of Reviews of Effects, Wiley), CENTRAl (Cochrane Central Register of Controlled Trials, Ovid), WHO, ICTRP (International Clinical Trials Registry Platform, ictrp portal) y ClinicalTrials, entre mayo y junio del 2020. Además, se selec- cionaron artículos originales, reportes de casos y artículos de revisión publicados en los últimos seis meses. No hubo restricción de idioma para permitir la recopilación de tantas publicaciones como fuera posible.
Genética‌‌ de‌‌ las‌‌ fisuras‌‌ labiopalatinas‌‌:‌ una‌‌ visión‌ general‌‌ de‌‌ los‌‌ factores‌‌ de‌‌ riesgo‌‌ genéticos‌‌ y‌‌ ambientales
Authors: Pusapaz Pusapaz Daniela Estefania , Arturo Terranova Maria Camila , Arturo Terranova Daniela
Published: August 2022

Las fisuras labiopalatinas son malformaciones congénitas del sistema estomatognático, se presentan por alteración de las estructuras anatómicas del cráneo, la cara y la cavidad bucal, debido a una falla en la fusión de tejidos en la embriogénesis; las malformaciones pueden ser del labio, el paladar duro, el velo del paladar, la mucosa palatina y en algunos casos de la cavidad nasal; por lo demás, afectan las estructuras que participan en las funciones del lenguaje, el habla y la audición. Objetivo: Identificar los factores genéticos y ambientales asociados a las fisuras labiopalatinas. Metodología: la revisión bibliográfica se realizó en bases de datos académicas PubMed, LILACS, OVID- MEDLINE usando lenguaje normalizado con términos DECS-LILACS: exposición a riesgos ambientales, fisura del paladar, labio leporino, genética, medicina de precisión y síndrome; se aplicaron filtros de búsqueda propios de las bases de datos, tipos de textos científicos e información relevante para la investigación. De acuerdo con los resultados de la búsqueda bibliográfica se encontró que la etio- logía de las fisuras es multifactorial y se asocia a factores genéticos y ambientales. La identificación de diversos genes relacionados con estas malformaciones ha permitido reconocer oportunamente cuándo una fisura es sindrómica o no sindrómica, lo que lleva a entender la interacción gen por gen, a identificar variantes funcionales y a comprender su importancia etiológica. Conclusiones: el estudio y el conocimiento acerca de los mecanismos moleculares que se encuentran involucrados en la formación de las fisuras labiopalatinas ha tomado fuerza gracias al entendimiento del genoma humano y al desarrollo de herramientas modernas de biología molecular que permiten identificar gran cantidad de datos de secuencia, haciendo que los genes candidatos aumenten constantemente. Esto permitirá un manejo oportuno de la enfermedad, la identificación del riesgo de ocurrencia y un tratamiento especializado mediante la medicina de precisión.