bluuebunny/crossref_metadata_2025 huggingface dataset:
Bearing capacity of eccentrically loaded strip footing on spatially variable cohesive soil
Authors: Dobrzański Jędrzej , Kawa Marek
Published: December 2021

The study considers the bearing capacity of eccentrically loaded strip footing on spatially variable, purely cohesive soil. The problem is solved using the random finite element method. The anisotropic random field of cohesion is generated using the Fourier series method, and individual problems within performed Monte Carlo simulations (MCSs) are solved using the Abaqus finite element code. The analysis includes eight different variants of the fluctuation scales and six values of load eccentricity. For each of these 48 cases, 1000 MCSs are performed and the probabilistic characteristics of the obtained values are calculated. The results of the analysis indicate that the mean value of the bearing capacity decreases linearly with eccentricity, which is consistent with Meyerhof's theory. However, the decrease in standard deviation and increase in the coefficient of variation of the bearing capacity observed are non-linear, which is particularly evident for small eccentricities. For one chosen variant of fluctuation scales, a reliability analysis investigating the influence of eccentricity on reliability index is performed. The results of the analysis conducted show that the value of the reliability index can be significantly influenced even by small eccentricities. This indicates the need to consider at least random eccentricities in future studies regarding probabilistic modelling of foundation bearing capacity.
formação inicial de professores e o ensino de língua materna
Authors: Raminho Edney Gomes , Silva Maria Cristina Mesquita da , Brito Renato de Oliveira
Published: December 2021

Este artigo analisa o contexto normativo atual da formação de professores de Língua Portuguesa como língua materna no Brasil, investigando especialmente a abordagem dada à multimodalidade, aos multiletramentos e à língua materna nos recentes regramentos nacionais da formação inicial de professores e da Educação Básica. Trata-se de uma pesquisa qualitativa documental cujos procedimentos calcaram-se em análise categorial temática e transversal de resultados a partir dos achados do estudo e teoria embasadora. À luz do diálogo teórico, constata-se que no tratamento da Língua Portuguesa como língua materna se mostra oportuno a ampliação do diálogo entre os normativos recentes, consoante a legislação basilar de educação brasileira, de modo que seja possível às licenciaturas em Letras aprimorarem a formação dos professores de Língua Portuguesa no Brasil, preparando-os na sua atuação para a apropriação da multimodalidade linguística e dos multiletramentos no processo de ensinar e aprender.
 
Recebido: 2/06/2021Aceite: 20/10/2021
José Alberto Correia – Para uma ética do cuidar e uma cidadania solidária
Authors: Medina Teresa , Ferreira Elisabete
Published: December 2021

José Alberto Correia é Professor Emérito da Universidade do Porto e Professor Catedrático da Faculdade de Psicologia e de Ciências da Educação da Universidade do Porto (FPCEUP). Ao longo da sua carreira académica e científica, foi diretor da FPCEUP, do Centro de Investigação e Intervenção Educativas (CIIE) e da Revista Educação, Sociedade e Culturas, tendo desempenhado diferentes funções de coordenação nos órgãos de gestão da faculdade e integrado instâncias de governo da Universidade do Porto. Na sua muito ampla investigação e produção científica, destacam-se trabalhos sobre epistemologia das ciências da educação, formação de professores, inovação pedagógica, relações entre formação e trabalho, educação de adultos, mediação socioeducativa e desenvolvimento local.
Automatic building of a large and complete dataset for image-based table structure recognition
Authors:   VNU University of Engineering and Technology, Quang Vinh Tran , Diep Nguyen Thi Ngoc ,   VNU University of Engineering and Technology
Published: December 2021

Table is one of the most common ways to represent structured data in documents. Existing researches on image-based table structure recognition often rely on limited datasets with the largest amount of 3,789 human-labeled tables as ICDAR 19 Track B dataset. A recent TableBank dataset for table structures contains 145K tables, however, the tables are labeled in an HTML tag sequence format, which impedes the development of image-based recognition methods. In this paper, we propose several processing methods that automatically convert an HTML tag sequence annotation into bounding box annotation for table cells in one table image. By ensembling these methods, we could convert 42,028 tables with high correctness, which is 11 times larger than the largest existing dataset (ICDAR 19). We then demonstrate that using these bounding box annotations, a straightforward representation of objects in images, we can achieve much higher F1-scores of table structure recognition at many high IoU thresholds using only off-the-shelf deep learning models: F1-score of 0.66 compared to the state-of-the-art of 0.44 for ICDAR19 dataset. A further experiment on using explicit bounding box annotation for image-based table structure recognition results in higher accuracy (70.6%) than implicit text sequence annotation (only 33.8%). The experiments show the effectiveness of our largest-to-date dataset to open up opportunities to generalize on real-world applications. Our dataset and experimental models are publicly available at shorturl.at/hwHY3
Multi-Layered Catastrophic Health Spending of Inpatient Women by Broad Group of Diseases in India
Authors:   Department of Public Health & Mortality Studies, International Institute for Population Sciences, India, Swargiary Manali , Lhungdim Hemkhothang ,   Department of Public Health & Mortality Studies, International Institute for Population Sciences, India, Bharadwaz Mrinmoy Pratim ,   Alpha MD Pvt Limited, India
Published: December 2021

Healthcare for Indian women needs prioritizing, as they continue to face social and economic discrimination over their healthcare, often with high out-of-pocket payments. The study examines the amount inpatient women have to pay for treatment of major diseases, re-classified into four groups as infectious, reproductive, non-communicable diseases (NCDs), and disabilities & injuries, across the country to comprehend the extent of catastrophic health spending (CHS) they experienced. The study is based on India’s 75th round of the National Sample Survey (NSS), i.e., Household Social Consumption: Health (2017-2018), consisting of 26,938 inpatient women aged 12 and above from India's urban and rural areas. We examine the prevalence of the four categories of diseases by individual, household, community, and healthcare characteristics. Expenditure estimates were derived from cross-tabulation, followed by binary logistic regression to assess the association between covariates and inpatient expenditures for the diseases. Indian women are more likely to be hospitalized for infectious diseases (43%), but the burden of CHS (overall) is highest for disabilities and injuries (INR 24,414), followed by NCDs (INR 23,053). Duration of hospitalization and possession of health insurance by women indicate maximum variation with medical spending. Almost 97% of women have incurred out-of-pocket expenditure on hospitalization, from which we identify three layers of CHS. A substantial proportion of women (23 to 50%) experienced CHS, i.e., up to 0-10%, 11-30%, and >30%, which varies distinctively by place of residence and across the six regions. Covariates like age, economic status, and healthcare are highly significant and associated with disease-wise CHS thresholds. Women in India face divergent financial hardships for healthcare. Given the heterogeneity of morbidities and socio-economic characteristics, the need for women-sensitive public health services and interventions are evident.
Clay figurine of an owl of the Lower Pritobolye
Authors: Turova Natalia
Published: December 2021

The object of this research is the clay figurine of an owl discovered in the course of archaeological excavations in the Yurtobor 9 hillfort on the right bank of the Tobol River. The goal lies in introduction of in the scientific discourse of the new unique sample of small clay plastic, as well as in preliminary determination of the functional purpose of the item. The following tasks were set: morphological and stylistic description of the item; description of the context of discovery of the figurine; establishment of the chronological framework of existence of the item, its cultural affiliation; familiarization with the history of studying the regional clay figurines in the Russian archaeological science; search for analogies in the archaeological sites of Siberia and other territories; assessment of the semantic connotation of the image of an owl in the traditional culture of Ob Ugrians (Khanty and Mansi). To article employs the traditional methods, such as comparative-historical, typological, comparative-typological, formal-stylistic, semantic methods, as well as method of analogies. As a result of the conducted research, the clay figurine of an owl is attributed to the Yudinskaya archaeological culture and dated within the framework of the XI – XII centuries. It is established that it is the only item in Western Siberian region depicting a bird in the technique of small clay plastic. Based on the analysis of ethnographic literature and medieval archaeological finds, it is established that for a long period of time, the image of an owl had positive semantic connotation due to its high sacred status. The author assumes on the use of figurine of an owl in religious rites associated with hearth and home.
Development of the Russian grain imports in the XIX – early XX centuries
Authors: Chistyakov Yurii Federovich
Published: December 2021

  The object of this research is the Russian imports of grain and grain products (flour and cereal) over the period from 1802 to 1917. The subject of this research is the dynamic processes of changes in the volume and commodity structure of the import of grain and grain products in the XIX – early XX centuries. The article leans on the analysis of sources that contain data on the Russian imports of grain and grain products (annual “Reviews of Russian foreign trade through European and Asian borders”), which characterizes import of grain to the Russian Empire of this period. The study employs the methods of historical, source studies, and statistical analysis. The analysis of sampling relies on the tabular summary of data and graphic representation of data. The novelty lies in the analysis of the key trends in the development of import of grain to the country throughout a prolonged historical period, which is carried out virtually for the first time. Based on examination of the statistical data in the import of grain, the following results were obtained: 1) a significant dependence of the volume of grain imports on the state of domestic grain production and the absence or presence of “lean years” in particular is underlined; 2) the periods of excess of grain imports over exports is determined. 3. The conclusion is made on the significant increase in the volume and transformation of the structure of the Russian grain imports in the beginning of the XX century. It is also indicated that due to insignificant volumes of import, compared to export, the grain imports did not affect the overall level of grain consumption among the Russian population.  
Approaches towards studying the concept of coping behavior in Russian and foreign scientific research
Authors: Tikhonova Elena Aleksandrovna
Published: December 2021

The subject of this research is the phenomenon of coping behavior in Russian and foreign scientific research. The object of this research is the approaches towards studying the concept of coping behavior. The goal lies in the attempt to systematize the approaches towards studying the concept of coping behavior in Russian and foreign scientific research. Methodology is based on the scientific-analytical review on the topic of coping behavior in the works of Russian and foreign researchers. The novelty lies in detailed examination such aspect as the approaches towards studying the concept of coping behavior in scientific research. It is underlined that the problem of coping behavior has been studied in foreign psychology since the 1960s; however, in Russian literature it is a fairly new direction. The theoretical framework for foreign research is comprised of the existing representations on the nature of psychological defense mechanisms, cognitive strategies, and stresses. Special attention is given to explanation why some individuals a resilient to stress, while others face difficulties to overcome stressful states. The author’s contribution lies in consideration of foreign experience and representations on the nature of psychological defense mechanisms, cognitive strategies, and stresses. The article analyzes coping behavior using the concepts of psychological defense, personal determinants, problem event, style of coping, pathological processes, and stress factor. The main conclusion is as follows: initially, an individual identifies a problem event as dangerous and unstable; and then, for choosing the way of coping, assesses the impact and characteristics of stress factor, and personal traits.
Koncepcja ochrony Dzieła Stworzenia i jej konteksty teologiczno-pedagogiczne w świetle czasopiśmiennictwa mariawickiego początku XX stulecia
Authors: Mames Tomasz Dariusz
Published: December 2021

Natura, uprawa roślin, hodowla zwierząt, ale także troska o higienę i dobrostan fizyczny oraz materialny człowieka, obok pracy duszpasterskiej, były ośrodkiem zainteresowania mariawitów od początku ich niezależności wyznaniowej. Na łamach periodyków wydawanych w mariawickiej drukarni w Łodzi w latach 1907–1914 (m.in. „Maryawita. Czciciel Przenajświętszego Sakramentu”, „Wiadomości Maryawickie”, kalendarz książkowy) znajdujemy konkretne porady, dotyczące pracy w gospodarstwie rolnym, ochrony mienia i zdrowia nie tylko ludzi, ale także zwierząt oraz roślin. Mariawici nie poprzestawali tylko na wymiarze prakseologicznym edukacji agrarnej, wskazując na filozoficzne i teologiczne podstawy ochrony stworzenia. W tym sensie łączyli praktykę z teorią ugruntowaną na przesłankach teologicznych, tworząc własną wizję tego, co współcześnie określamy mianem ekoteologii i ekopedagogiki. Refleksja i praktyka proekologiczna stanowiły integralny element ideologii oświatowej Kościoła mariawickiego, wyrosłej z idei pozytywistycznych.Wpisuje się ona w narrację, ukazującą prymat przykazania miłości Boga i bliźniego. Jej aktualność dostrzec możemy poprzez bliski związek z myśleniem krytycznym i odwołującą się do niego ekopedagogiką, jak również szeroko rozumianym zwrotem ekologicznym w teologii oraz życiu społecznym i gospodarczym.
Hubungan Conscientiousness dengan Pertimbangan Protokol Kesehatan dalam Perilaku Konsumsi selama Pandemi Covid-19
Authors: Rubianto Liroy , Nathania Alexandrina J. , Prawesthy Gisela A. , - Jessica , Mutalim Hanarolisa , Yosua Immanuel , Dahesihsari Rayini
Published: December 2021

The Covid-19 pandemic is a major problem that is currently faced worldwide. As an effort to minimize this problem, the government enforces a health protocol appeal for the Indonesian citizens. The change in the situation affects people’s lives, especially in the economic and trade sector in Indonesia. One of the impacts is a change in people’s assumptions in assessing a product. Currently, health protocols are one of the considerations in consuming products during the pandemic, so that people move to products that can protect themselves from the transmission of Covid-19. The changes in consumer behavior can be explained through one of the dimensions of the Big Five Personality, namely conscientiousness. Conscientiousness can describe individual behavior in maintaining their own health. Therefore, this study wants to see whether there is a relationship between the conscientiousness and the consideration of health protocols in product consumption during the Covid-19 pandemic. This study uses a quantitative approach, with correlational research design. Based on the results of data analysis using Spearman’s Rank Order Correlation, the value obtained was ???????? (1056) = 0.256, p < 0.001. Therefore, it can be concluded that there is a significant relationship between conscientiousness and the consideration of health protocols in product consumption during pandemic.
Hubungan Antara Psychological Capital dengan Subjective Career Success pada Karyawan Generasi Milenial
Authors: Tania Puji , Rosari Maria Catalina
Published: December 2021

This study aims to determine the relationship between psychological capital and subjective career success in millennial generation employees. This study involved 129 millennial generation employees. The type of design of this research is correlational. The measuring instrument used of two questionnare, namely psychological capital questionnaire (PCQ) and subjective career success inventory (SCSI). Data processing with Pearson correlation. The results showed that there is a significant positive relationship between psychological capital and subjective career success in millennial generation employees (r(127)=0.551, sig (2-tailed)=0.000). Thus, the higher the psychological capital owned by millennial generation employees, the higher the subjective career success of millennial employees.

 

Penelitian ini bertujuan mengetahui hubungan antara psychological capital dengan subjective career success pada karyawan generasi milenial. Penelitian ini melibatkan 129 karyawan generasi milenial. Subjek dipilih menggunakan teknik convenience sampling. Jenis desain dari penelitian ini adalah korelasional. Alat ukur yang digunakan terdiri dari dua alat ukur, yaitu psychological capital questionnaire (PCQ) dan subjective career success inventory (SCSI). Pengolahan data dengan uji korelasi pearson. Hasil penelitian menunjukkan bahwa terdapat hubungan positif yang signifikan antara psychological capital dengan subjective career success pada karyawan generasi milenial (r(127)=0.551, sig (2-tailed)=0.000). Dengan demikian, semakin tinggi psychological capital yang dimiliki oleh karyawan generasi milenial maka semakin tinggi subjective career success karyawan generasi milenial.
Gambaran Parental Mediation Ibu pada Pengguna Internet Usia Remaja
Authors: Pristinella Debri , Desiyanthi Revina
Published: December 2021

Internet telah menjadi media utama yang digunakan remaja untuk kebutuhan pendidikan. Oleh karena itu, orang tua mau tidak mau memberikan fasilitas internet kepada remaja. Dengan adanya fasilitas pribadi, internet juga digunakan sebagai media mencari informasi, hiburan, komunikasi, dan bertransaksi. Hal ini menjadi masalah bagi orang tua karena internet dapat memberikan dampak negatif seperti terpaparnya konten-konten negatif, cyberbullying, dan ketergantungan internet. Oleh karena itu, parental mediation perlu dilakukan menjaga penggunaan internet pada remaja untuk memaksimalkan dampak positif dan meminimalisir dampak negatif internet.

Penelitian ini bertujuan untuk mendapatkan gambaran mengenai parental mediation seperti apa yang digunakan oleh orang tua terhadap anak-anak remaja mereka yang merupakan pengguna internet serta faktor apa saja yang mempengaruhinya. Penelitian ini menggunakan metode kualitatif dengan melakukan wawancara semi tersruktur pada tiga ibu yang memiliki anak berusia dua belas hingga dua puluh satu tahun dan memiliki akses internet sendiri. Ibu menjadi fokus peneliti karena ibu memiliki waktu lebih banyak dibandingkan ayah dalam membesarkan, mengurus, dan mendisiplinkan anak.Hasil penelitian kemudian dianalisis menggunakan teknik analisis konten. Peneliti juga melakukan triangulasi kepada anak dari setiap orang tua untuk meningkatkan validitas data.

Hasil penelitian menunjukkan bahwa orang tua menerapkan kelima strategi parental mediation terutama strategi active mediation of internet use dan active mediation of internet safety. Penelitian juga menunjukkan bahwa parental mediation dipengaruhi oleh empat faktor yaitu kemampuan orang tua dalam menggunakan internet, karakteristik perkembangan anak, persepsi orang tua terhadap kontrol diri anak, dan sikap orang tua terhadap internet.
Representasi Sosial tentang Tragedi Semanggi pada Mahasiswa Unika Atma Jaya
Authors: Prawiro Ferdinand , Rahma Sarah Andruina
Published: December 2021

Peristiwa Tragedi Semanggi terjadi pada tanggal 13 November 1998. Hampir setiap tahun terdapat kelompok mahasiswa Unika Atma Jaya melakukan aksi memperingati Tragedi Semanggi walaupun mereka tidak mengalami langsung peristiwa tersebut. Namun sebagian besar mahasiswa tidak ikut memperingati Tragedi Semanggi. Penelitian ini bertujuan memahami perbedaan keterlibatan dalam aksi peringatan Tragedi Semanggi melalui konsep representasi sosial, dengan pendekatan struktural. Pendekatan ini memandang bahwa isi representasi sosial suatu kelompok mencakup dua sistem, yaitu central core dan peripheral.

Metode penelitian ini berjenis kuantitatif dan melalui dua tahap. Tahap pertama bertujuan mengidentifikasi atribut representasi sosial tentang Tragedi Semanggi, dan tahap kedua bertujuan mengidentifikasi atribut mana yang berada di central core dan peripheral. Penelitian ini melibatkan 230 partisipan pada tahap pertama dan 206 partisipan pada tahap kedua, yang diperoleh melalui accidental sampling. Data penelitian diperoleh dengan kuesioner online dengan teknik word association pada tahap pertama dan teknik calling-into-question pada tahap kedua. Analisis data tahap pertama menggunakan content analysis, sedangkan pada tahap kedua menggunakan chi-square goodness of fit dengan ⅔ expected frequency.

Hasil penelitian menemukan 18 atribut representasi sosial tentang Tragedi Semanggi, yaitu: “korban”, “mahasiswa”, “situasi yang kacau”, “demonstrasi”, “aparat negara”, “perilaku kekerasan”, “perlawanan”, “pelanggaran hukum dan HAM”, “Atma Jaya”, “perasaan takut”, “masa lalu”, “pemerintah”, “reformasi”, “ketidakadilan”, “politik”, “belum selesai”, “orde baru”, “perasaan sedih”. Perbedaan antara kelompok partisipan aksi dan kelompok nonpartisipan aksi terletak pada atribut “belum selesai” dan “reformasi”.
Desenvolvimento de uma tecnologia educacional para pais e/ou cuidadores de crianças com Alergia à Proteína do Leite de Vaca (APLV)
Authors: Rodrigues Eva Lorena Jaques , Mori Rejane Maria Sales Cavalcante , Figueiredo Sandra Maria dos Santos
Published: December 2021

Objetivo: Descrever o processo de produção de uma tecnologia educacional sobre Alergia à Proteína do Leite de Vaca (APLV) a partir das percepções de pais e/ou cuidadores de crianças com esta condição. Métodos: Pesquisa descritiva, quali-quantitativa, desenvolvida em uma Unidade Básica de Saúde onde funciona o Programa de alergia alimentar na região Norte. Foram avaliados 65 pais e/ou cuidadores. Foi utilizado um formulário e entrevista semiestruturada, a fim de nortear a produção da tecnologia. Os registros foram analisados por meio da análise categorial-temática. Resultados: A análise originou três categorias: Conhecer a APLV, a alimentação e seus desafios e dificuldades e o cuidado com a criança e o apoio familiar, que subsidiaram a construção da tecnologia educacional, que após sua validação, contribuirá para o cuidado à criança com APLV. A cartilha contém 49 páginas e 11 tópicos de conteúdo, com textos e imagens. Conclusão: A construção de tecnologias educacionais é uma potencial ferramenta de educação em saúde para favorecer a autonomia, promover saúde e estimular o cuidado seguro, com base nas reais necessidades dos pais e/ou cuidadores de crianças com APLV.
Apert syndrome: A dermatologist’s perspective
Authors: Kamra Nidhi , Tuknayat Ankita
Published: December 2021

Apert syndrome is a Type 1 acrocephalosyndactyly syndrome presenting predominantly with craniofacial malformations and syndactyly. It can present with a multitude of clinical features involving any system of the body. A literature search of the PubMed electronic database was performed using the keywords “Apert syndrome” and “dermatology” in the title. The relevant references of the included articles were traced and included. A total of 27 articles appeared, the abstracts of which were screened and reviewed by both the authors independently for inclusion. After carefully analyzing all papers case by case, 21 such cases were retrieved. Cases presenting with other clinical features apart from dermatological features were also reviewed but were not included in the table. A total of about 30 patients of Apert syndrome have been described in dermatological literature, acne being the most common dermatological manifestation. Predominant clinical features in all the cases were brachycephaly due to craniosynostosis and syndactyly of hands and feet. Most of the patients had skeletal, dental, gastrointestinal, genitourinary, respiratory, cardiovascular, and dermatological manifestations in varying proportions. Apert syndrome is a rare entity which can present to a dermatologist. It is, therefore, pertinent to be able to diagnose and recognize the various clinical features of this syndrome to ensure timely management of such patients.
On the Selection of a Method Allowing to Evaluate the Sensitivity of a Model to Its Parameters within the Safety Assessment of RW Disposal Facilities
Authors:   Nuclear Safety Institute of the Russian Academy of Sciences, Saveleva E. A. , Svitelman V. S. ,   Nuclear Safety Institute of the Russian Academy of Sciences, Blinov P. D. ,   Nuclear Safety Institute of the Russian Academy of Sciences, Valetov D. K. ,   Nuclear Safety Institute of the Russian Academy of Sciences, Gorelov M. M. ,   Nuclear Safety Institute of the Russian Academy of Sciences
Published: December 2021

The paper proposes a methodology enabling the selection of a method for parameter sensitivity assessment during numerical model development and its parametrization. Sensitivity analysis is considered essential for uncertainty analysis, which is provided for under relevant international guidelines on the safety assessment of RW disposal facilities, as well as federal rules and regulations in the field of atomic energy use. The paper provides some case studies on the application of the proposed approach.
Approaches to the Characterization of Graphite UGR Blocks Based on Beta-emitting 14С and 36Сl Radionuclides. Testing at RBMK-1000-type Reactors
Authors:   “Pilot & Demonstration Center for Decommissioning of Uranium-Graphite Nuclear Reactors”, JSC, Pavliuk А. О. , Kotlyarevsky S. G. ,   “Pilot & Demonstration Center for Decommissioning of Uranium-Graphite Nuclear Reactors”, JSC, Kan R. I. ,   “Pilot & Demonstration Center for Decommissioning of Uranium-Graphite Nuclear Reactors”, JSC, Volkova А. G. ,   Federal State Budgetary Institution of Science А. N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences, Zakcharova E. V. ,   Federal State Budgetary Institution of Science А. N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences, Ilyukhina M. А. ,   JSC “A. A. Bochvar High-Technology Research Institute of Inorganic Materials”, Gorshkov V. B. ,   JSC “A. A. Bochvar High-Technology Research Institute of Inorganic Materials”, Dorofeev А. N. ,   State Corporation “Rosatom”, Zinnurov B. S. ,   State Corporation “Rosatom”, Komarov Е. А. ,   State Corporation “Rosatom”
Published: December 2021

This paper presents some methodological approaches to the characterization of graphite blocks based on difficultto-measure 14C and 36Cl radionuclides during graphite stack dismantlement at uranium-graphite reactors (UGR) developed by JSC PDC UGR. It presents the testing results of the developed methods applied during RBMK-1000 graphite stack block characterization at the Leningrad NPP.
Spent Ion Exchange Resin Conditioning Technology Based on Thermal Vacuum Drying Method
Authors:   JSC “ATOMPROEKT”, Sorokin V. T. , Prohorov N. A. ,   JSC “ATOMPROEKT”, Pavlov D. I. ,   Saint-Petersburg branch of JSC “FCNIVT “SNPO “ELERON” — “VNIPIET”
Published: December 2021

The article deals with the issues associated with the conditioning of intermediate- and low-level spent ion exchange resins (IOS) by thermal vacuum drying method to obtain packages that would meet the acceptance criteria set for near-surface disposal. The paper describes an experimental installation and the industrial technology of OIOS dehumidification. For air conditioning of intermediate-level OIOS, it proposes the use of certified reinforced concrete containers. As it comes to the conditioning of low–level OIOS, it proposes plastic containers being similar in their designs to the metal ones. The paper also evaluates the compliance of OIOS packages with relevant safety requirements.
Silver recovery from radioactive waste generated due to the disposition of silver-containing products
Authors:   FSUE Mayak PA, Kuznetsova N. А. , Sakhnenko О. А. ,   FSUE Mayak PA, Kharlova А. G. ,   FSUE Mayak PA, Lyzlova Ye. V. ,   FSUE Mayak PA, Zimin P. Yu. ,   FSUE Mayak PA
Published: December 2021

The studies performed resulted in the development of a method enabling silver recovery from radioactively contaminated silver-containing products. This method includes the following stages: preliminary decontamination of products, dissolution of silver product fragments in a nitric acid solution, production of finely dispersed silver by displacement of silver metal with copper, submerged melting of finely dispersed silver at a temperature of at least 960°С. To reduce the operating costs, evaluated was the feasibility of silver recovery from its compounds (chloride, sulphate and oxide).
Approaches to graphite block characterization by gamma radionuclides and their packaging during UGR stack dismantlement
Authors:   “Pilot & Demonstration Center for Decommissioning of Uranium-Graphite Nuclear Reactors”, JSC, Pavliuk А. О. , Kotlyarevsky S. G. ,   “Pilot & Demonstration Center for Decommissioning of Uranium-Graphite Nuclear Reactors”, JSC, Kan R. I. ,   “Pilot & Demonstration Center for Decommissioning of Uranium-Graphite Nuclear Reactors”, JSC, Volkova A. G. ,   Federal State Budgetary Institution of Science А. N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences, Zakcharova E. V. ,   Federal State Budgetary Institution of Science А. N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences, Komarov E. A. ,   State Corporation “Rosatom”
Published: December 2021

This paper presents technical and methodological approaches developed by PDC UGR to characterize the removed graphite blocks by gamma-emitting radionuclides during graphite stack dismantlement and to enable their packaging. It overviews the experimental testing of the characterization method and its findings. It also presents container design option allowing to achieve the maximum filling efficiency.
Assessing the mobility of clay materials used in the construction of engineered safety barriers for radioactive waste disposal
Authors:   ", Maryinskikh S. G. ,   Bentonite Company” Ltd., Zhigarev V. V. ,   "Bentonite Company” Ltd., Ilyina O. A. ,   “Bentonite of Khakassia” Ltd., Krupskaya V. V. ,   Nuclear Safety Institute of the Russian Academy of Sciences
Published: December 2021

Large-scale efforts implemented under the Unified State System for RW Management including the construction of near-surface disposal facilities for RW Class 3 and 4, as well as provision of long-term safety at nuclear legacy facilities require the scientific community to develop systems of engineered safety barriers preventing radionuclide releases into the environment. In the near future, at least 70 storage facilities for non-retrievable RW will require the installation of such barrier systems. The quality of barrier materials constituting to the system of engineered safety barriers (EBS), including their ability of providing a uniform backfilling of cavities inside the structures, is viewed as an important design parameter requiring proper assessment both under the production control of materials and quality control of designed EBS, including relevant in situ testing.
Two-Decade Retrospective of German-Russian Cooperation in the Field of Safe Radioactive Waste Management
Authors:   Federal State Budgetary Institution of Science Institute of Geology of Ore Deposits, Petrography, Mineralogy and Geochemistry of the Russian Academy of Sciences, Petrov V. A. , Krone J ,   BGE TECHNOLOGY GmbH, Kamnev E. N. ,   JSC Leading Design and Survey and Research Institute of Industrial Technology, Timayer T. ,   Federal Office for Geosciences and Natural Resources (BGR)
Published: December 2021

This paper briefly overviews a two-decade retrospective of a fruitful cooperation between German and Russian departments and experts in such a sensitive, high-tech and science-intensive area as radioactive waste disposal. The paper indicates the kea areas of this cooperation, as well as the most important results achieved.
Shape memory textiles – technological background and possible applications
Authors: Ehrmann Guido , Ehrmann Andrea
Published: December 2021

While shape memory alloys (SMAs) and shape memory polymers (SMPs) can already be found in diverse applications, shape memory textiles are less often used. Nevertheless, they are regularly investigated. Typical ways to produce shape memory textiles (SMTs) are introducing shape memory wires, printing shape memory polymers on them (“4D printing”), or using textile materials such as poly(lactic acid) (PLA) which show shape memory properties on their own. This review gives a brief overview of these technological possibilities and possible applications of shape memory textiles.
Tata Kelola Teknologi Informasi Menggunakan Framework COBIT 2019 (Studi Kasus: UPT TIK Universitas Tanjungpura Pontianak)
Authors: Sukamto Anggi Srimurdianti , Novriando Haried , Reynaldi Aldi
Published: December 2021

UPT TIK UNTAN merupakan suatu lembaga yang melakukan pengelolaan TI. Tata kelola TI mencakup kepemimpinan, struktur serta proses organisasi yang memastikan bahwa TI dimanfaatkan seoptimal mungkin dan berkonsentrasi pada kinerja dan transformasi TI untuk memenuhi kebutuhan saat ini dan yang akan datang, baik dari sudut internal maupun eksternal. COBIT 2019 adalah kerangka kerja untuk tata kelola dan manajemen informasi dan teknologi perusahaan. Sedangkan COBIT Performance Management merupakan model yang berisi kerangka dasar dalam memberikan panduan untuk menilai dan mengukur tingkat kapabilitas dan tingkat kematangan yang berkaitan dengan proses tata kelola dan manajemen TI. Hasil pengukuran tata kelola TI pada UPT TIK UNTAN dinyatakan bahwa tingkat kapabilitas proses APO08 (Managed Relationships) yang dicapai berada pada tingkat 5. Tingkat kapabilitas proses APO09 (Managed Service Agreements) yang dicapai berada pada tingkat 1. Sedangkan tingkat kapabilitas proses APO11 (Managed Quality) yang dicapai berada pada tingkat 2. Kesenjangan antara tingkat kapabilitas proses saat ini dan tingkat kapabilitas harapan pada objektif proses APO08 bernilai 0, sedangkan pada objektif proses APO09 dan APO11 bernilai -1. Pada objektif proses APO09 kesenjangannya 2%, sedangkan pada objektif proses APO11 kesenjangannya 8%. Berdasarkan hasil analisis, maka diberikan rekomendasi perbaikan yang mengacu pada COBIT 2019 untuk meningkatkan tingkat kapabilitas harapan.
Experimental validation of an adsorbent-agnostic artificial neural network (ANN) framework for the design and optimization of cyclic adsorption processes
Authors: Pai Kasturi Nagesh , Nguyen Tai T.T. , Prasad Vinay , Rajendran Arvind
Published: December 2021

The efficacy of an adsorbent agnostic machine-learning surrogate model for rapid design and optimization of a Skarstrom cycle vacuum swing adsorption (VSA) process is experimentally validated. The surrogate model is trained to predict the process performance using adsorbent features that include hypothetical Langmuir adsorption isotherm parameters, particle density, porosity and bed voidage, and process variables such as pressure, step duration and feed velocity. The training data was generated from a detailed process model for 20,000 unique combinations of the training variables. The model shows high accuracy of R2adj>0.99 for predicting key performance parameters such as product purity, recovery and productivity. The ability of this surrogate to predict the experimental performance for the purification of O2 from the air on two adsorbents, namely 13X and LiX zeolites, was studied. Two separate multi-objective optimization studies, to maximize purity and recovery, and to maximize productivity and purity were performed. For these optimization studies, the volumetrically measured isotherms of N2 and O2 were used as inputs to the surrogate model. Note that these isotherms were not a part of the dataset used to train the model. Nine points were chosen from the Parteo curves and the corresponding decision variables were used as set-points in a two-column lab-scale rig. The average difference between the calculated and experimentally measured purity, recovery and productivity was 3%, 5% and 9%, respectively. This study provides the necessary confidence to use surrogate-based process models for adsorbent screening and adsorption process optimization.
Coarse-grained molecular models of the surface of hair
Authors: Weiand Erik , Ewen James P. , Koenig Peter H. , Roiter Yuri , Page Steven H. , Angioletti-Uberti Stefano , Dini Daniele
Published: December 2021

We present a coarse-grained molecular model of the surface of human hair, which consists of a lipid monolayer, in the MARTINI framework. Using molecular dynamics simulations, we identify a lipid grafting distance that yields a monolayer thickness consistent with atomistic simulations and experimental measurements of hair surfaces. Coarse-grained models for fully-functionalised, partially damaged, and fully damaged hair surfaces are created by randomly replacing neutral thioesters with anionic sulfonate groups. This mimics the progressive removal of fatty acids from the hair surface by bleaching. We study the structure of the lipid monolayer at different degrees of damage using molecular dynamics simulations in vacuum as well as in polar (water) and non-polar (n-hexadecane) solvents. We also compare the wetting behaviour of water and n-hexadecane on the hair surfaces through contact angle measurements conducted using molecular dynamics simulations and experiments. Our model captures the experimentally-observed transition of the hair surface from hydrophobic (and oleophilic) to hydrophilic (and oleophobic) as the level of bleaching damage increases. By using surfaces with different damage ratios, we obtain contact angles from the simulations that are in good agreement with experiments for both solvents on virgin and bleached human hairs. In both the molecular dynamics simulations and further experiments using biomimetic surfaces, the cosine of the water contact angle increases linearly with the sulfonate group surface coverage. We expect that the proposed systems will be useful for future molecular dynamics simulations of the adsorption and tribological behaviour of hair surfaces.
KiSSim: Predicting off-targets from structural similarities in the kinome
Authors: Sydow Dominique , Aßmann Eva , Kooistra Albert J. , Rippmann Friedrich , Volkamer Andrea
Published: December 2021

Protein kinases are among the most important drug targets because their dysregulation can cause cancer, inflammatory, and degenerative diseases. Developing selective inhibitors is challenging due to the highly conserved binding sites across the roughly 500 human kinases. Thus, detecting subtle similarities on a structural level can help to explain and predict off-targets among the kinase family. Here, we present the kinase-focused and subpocket-enhanced KiSSim fingerprint (Kinase Structural Similarity). The fingerprint builds on the KLIFS pocket definition, composed of 85 residues aligned across all available protein kinase structures, which enables residue-by-residue comparison without a computationally expensive alignment. The residues' physicochemical and spatial properties are encoded within their structural context including key subpockets at the hinge region, the DFG motif, and the front pocket. Since structure was found to contain information complementary to sequence, we used the fingerprint to calculate all-against-all similarities within the structurally covered kinome. Thereby, we could identify off-targets that are unexpected if solely considering the sequence-based kinome tree grouping; for example, Erlobinib’s known kinase off-targets SLK and LOK show high similarities to the key target EGFR (TK group) though belonging to the STE group. KiSSim reflects profiling data better or at least as well as other approaches such as KLIFS pocket sequence identity, KLIFS interaction fingerprints (IFPs), or SiteAlign. To rationalize observed (dis)similarities, the fingerprint values can be visualized in 3D by coloring structures with residue and feature resolution. We believe that the KiSSim fingerprint is a valuable addition to the kinase research toolbox to guide off-target and polypharmacology prediction. The method is distributed as an open-source Python package on GitHub and as conda package: https://github.com/volkamerlab/kissim
Robust organic cages prepared using hydrazone condensation display sulfate/hydrogenphosphate selectivity in water
Authors: Foyle Emer , Mason Thomas , Coote Michelle , Izgorodina Ekaterina , White Nicholas
Published: December 2021

Two robust hexacationic cages incorporating either urea or isophthalamide motifs were synthesized via a short and high-yielding synthetic pathway using hydrazone condensation reactions in water for the cage forming step. Stability testing revealed that the cages are stable to a range of stimuli in water and in organic solvents. The urea containing cage can bind anions in pure water, and displays strong and selective binding of SO42– over HPO42–. The isophthalamide containing cage binds SO42– only weakly in 1:1 D2O:d6-DMSO but displays strong and cooperative binding of two HPO42– anions. Combined quantum mechanical/annealed molecular dynamics simulations suggest that the remarkable differences in anion selectivity are largely a result of the differing flexibilities of the two cages.
Large Scale Study of Ligand-Protein Relative Binding Free Energy Calculations: Actionable Predictions from Statistically Robust Protocols
Authors: Bhati Agastya P , Coveney Peter V.
Published: December 2021

The accurate and reliable prediction of protein-ligand binding affinities can play a central role in the drug discovery process as well as in personalised medicine. Of considerable importance during lead optimisation are the alchemical free energy methods that furnish estimation of relative binding free energies (RBFE) of similar molecules. Recent advances in these methods have increased their speed, accuracy and precision. This is evident from the increasing number of retrospective as well as prospective studies employing them. However, such methods still have limited applicability in real-world scenarios due to a number of important yet unresolved issues. Here, we report the findings from a large dataset comprising over 500 ligand transformations spanning over 300 ligands binding to a diverse set of 14 different protein targets which furnish statistically robust results on the accuracy, precision and reproducibility of RBFE calculations. We use ensemble-based methods which are the only way to provide reliable uncertainty quantification given that the underlying molecular dynamics is chaotic. These are implemented using TIES (Thermodynamic Integration with Enhanced Sampling) but are equally applicable to free energy perturbation calculations for which we expect essentially very similar results. Results achieve chemical accuracy in all cases. Ensemble simulations also furnish information on the statistical distributions of the free energy calculations which exhibit non-normal behaviour. We find that the “enhanced sampling” method known as replica exchange with solute tempering degrades RBFE predictions. We also report definitively on numerous associated alchemical factors including the choice of ligand charge method, flexibility in ligand structure and the size of the alchemical region including the number of atoms involved in transforming one ligand into another. Our findings provide a key set of recommendations that should be adopted for the reliable application of RBFE methods.
Systems of Inclusions with Unknowns in Multioperations
Authors:   Saint Petersburg Electrotechnical University ”LETI”, Peryazev N. A.
Published: December 2021

We consider systems of inclusions with unknowns and coefficients in multioperations of finite rank. An algorithm for solving such systems by the method of reduction to Boolean equations using superposition representation of multioperations by Boolean space matrices is given. Two methods for solving Boolean equations with many unknowns are described for completeness. The presentation is demonstrated by examples: the representation of the superposition of multioperations by Boolean space matrices; solving a Boolean equation by analytical and numerical methods; and finding solutions to an inclusion with one unknown. The resulting algorithm can be applied to the development of logical inference systems for multioperator logics.
To the 50th Anniversary of the Department of Probability Theory and Discrete Mathematics of Irkutsk University
Authors:   Irkutsk State University, Kuzmin O. V.
Published: December 2021

The article provides a brief overview of the history milestones of scientific and pedagogical activity and the achievements of the Department of Probability Theory and Discrete Mathematics of Irkutsk State University for 50 years since its foundation.
About Formal Normal Form of the Semi-Hyperbolic Maps Germs on the Plane
Authors:   Chelyabinsk State University, Shaikhullina P. A.
Published: December 2021

There are consider the problem of constructing an analytical classification holomorphic resonance maps germs of Siegel-type in dimension 2. Namely, semi-hyperbolic maps of general form: such maps have one parabolic multiplier (equal to one), and the other hyperbolic (not equal in modulus to zero or one). In this paper, the first stage of constructing an analytical classification by the method of functional invariants is carried out: a theorem on the reducibility of a germ to its formal normal form by "semiformal" changes of coordinates is proved. The one-time shift along the saddle node vector field (the formal normal form in the problem of the analytical classification of saddle-node vector fields on a plane) is chosen as the formal normal form.
Deep Learning of Adaptive Control Systems Based on a Logical-probabilistic Approach
Authors:   Ershov Institute of Informatics Systems, Demin A. V.
Published: December 2021

The problem of automatic selection of subgoals is currently one of the most relevant in adaptive control problems, in particular, in Reinforcement Learning. This paper proposes a logical-probabilistic approach to the construction of adaptive learning control systems capable of detecting deep implicit subgoals. The approach uses the ideas of the neurophysiological Theory of functional systems to organize the control scheme, and logical-probabilistic methods of machine learning to train the rules of the system and identify subgoals. The efficiency of the proposed approach is demonstrated by an example of solving a three-stage foraging problem containing two nested implicit subgoals