bluuebunny/crossref_metadata_2025 huggingface dataset:
O PAPEL DAS MÍDIAS SOCIAIS NO RELACIONAMENTO ENTRE HOSPITAIS E SEUS DIFERENTES PÚBLICOS: UM ESTUDO DE CASO EM UMA REDE HOSPITALAR DE GRANDE PORTE
Authors: Favaro Priscila , Leite Ramon Silva , Prado Noélia Pereira , Farias Valcir Marcilio
Published: April 2018

As mídias sociais provocaram grandes transformações na relação entre organizações, clientes e demais envolvidos. Esse estudo buscou analisar o papel das redes sociais no relacionamento entre uma rede hospitalar privada de grande porte e seus diferentes públicos. Foi conduzido um estudo de caso, que contou com triangulação de fonte e de métodos. Foram analisadas as interações feitas pelos usuários nas mídias sociais da rede ao longo de doze meses. Complementarmente foi conduzida uma observação do processo de gerenciamento das redes sociais pela instituição. Verificou-se que, com a compreensão das redes sociais como canal estratégico de interação com seus diversos públicos, a organização pesquisada passou a ter participação mais efetiva e retorno mais significativo de suas ações. A utilização das mídias sociais como estratégia de marketing favoreceu o relacionamento por meio das diversas formas de interação, engajamento e publicidade. Ressalta-se que o processo de monitoramento e resposta às redes sociais deve estar inserido em um fluxo de trabalho estruturado, sendo esse um canal novo, mas promissor para o estreitamento do relacionamento entre hospitais e seus diferentes públicos.
FATORES DE QUALIDADE DE VIDA NO TRABALHO E SUCESSO NA CARREIRA: UM ESTUDO COM MÉDICOS DA CIDADE DE BELO HORIZONTE
Authors: Venelli-Costa Luciano , Rodrigues Carolina Laender Moura Muñoz , Kilimnik Zélia Miranda , Mesquita Jose Marcos Carvalho de
Published: April 2018

A carreira médica caracteriza-se pela renúncia do controle do tempo em troca de dinheiro, status, segurança e respeito. A necessidade de atualização constante é outra característica típica da medicina, com um longo curso de graduação, seguido por residências médicas e outras especializações, mestrado e doutorado. Este estudo teve como objetivo analisar quais dimensões da Percepção de Sucesso na Carreira (Venelli-Costa, 2013) são mais influenciadas pela Qualidade de Vida no Trabalho (Walton, 1973), no que se refere à carreira médica. Uma pesquisa quantitativa foi realizada  220 com médicos de Belo Horizonte, em sua maioria do setor público. Os resultados mostram que há grande relação entre os fatores de Qualidade de Vida no Trabalho e Percepção de Sucesso na Carreira. E confirmam forte relação entre os construtos uma vez que três fatores - Compensação justa e adequada; Uso e desenvolvimento de capacidades; e Relevância social do trabalho na vida - explicaram significativamente a percepção de sucesso em termos de Identidade, Remuneração, Hierarquia, Empregabilidade, Competência e Valores. Além disso, confirmou-se a proximidade entre os fatores Trabalho e o espaço total de vida; e Equilíbrio vida-trabalho.
Processo de tomada de decisões: estudo multicaso comparativo em organizações hospitalares de belo horizonte
Authors: Dias Alexandre Teixeira , Berti Shirley Dabus
Published: April 2018

Este estudo aborda a influência da estrutura organizacional e do processo de tomada de decisão no desempenho de seis hospitais de grande porte, filantrópicos, sediados em Belo Horizonte - MG. A pesquisa é qualitativa, descritiva e de campo, utilizando-se de entrevistas semiestruturadas, feitas com um dos tomadores de decisões estratégicas de cada hospital, com posterior análise de conteúdo, permitindo a retirada de dados para se atingirem os objetivos propostos. Os resultados encontrados indicaram influências da configuração estrutural e do processo de tomada de decisão no desempenho organizacional e que todos são conservadores em seus investimentos, escolhendo o baixo risco, mas sem prejudicar a qualidade da assistência prestada ao paciente. As especialidades em clínicas médicas, ortopedia, geriatria, cirurgia e obstetrícia, entre outras, são consideradas uma vantagem competitiva para cada um dos seis hospitais. As influências dos fatores coincidentes identificados entre a configuração estrutural, a tomada de decisão e o desempenho organizacional não seguem um padrão único, sendo que cada hospital pesquisado apresenta relação distinta com as referidas variáveis.
Surface to sewer flow exchange through circular inlets during urban flood conditions
Authors: Rubinato Matteo , Lee Seungsoo , Martins Ricardo , Shucksmith James D.
Published: April 2018

Accurately quantifying the capacity of sewer inlets (such as manhole lids and gullies) to transfer water is important for many hydraulic flood modelling tools. The large range of inlet types and grate designs used in practice makes the representation of flow through and around such inlets challenging. This study uses a physical scale model to quantify flow conditions through a circular inlet during shallow steady state surface flow conditions. Ten different inlet grate designs have been tested over a range of surface flow depths. The resulting datasets have been used (i) to quantify weir and orifice discharge coefficients for commonly used flood modelling surface–sewer linking equations and (ii) to validate a 2D finite difference model in terms of simulated water depths around the inlet. Calibrated weir and orifice coefficients were observed to be in the range 0.115–0.372 and 0.349–2.038, respectively, and a relationship with grate geometrical parameters was observed. The results show an agreement between experimentally observed and numerically modelled flow depths but with larger discrepancies at higher flow exchange rates. Despite some discrepancies, the results provide improved confidence regarding the reliability of the numerical method to model surface to sewer flow under steady state hydraulic conditions.
A fractional-order infiltration model to improve the simulation of rainfall/runoff in combination with a 2D shallow water model
Authors: Fernández-Pato J. , Gracia J. L. , García-Navarro P.
Published: April 2018

In this work, a distributed two-dimensional (2D) shallow water (SW) flow model is combined with a fractional-order version of the Green-Ampt (FOGA) infiltration law to improve rainfall/runoff simulation in real catchments. The surface water model is based on a robust finite volume method on triangular grids that can handle flow over dry bed and multiple wet/dry fronts. When supplied with adequate infiltration laws, this model can provide useful information in surface hydrology. The classical Green-Ampt law is generalized by using a Caputo fractional derivative of order less than or equal to 1 in Darcy's law. The novelty of this combination is that, on the one hand, the distributed SW simulation provides a detailed surface water distribution and, on the other hand, the FOGA model offers the possibility to model infiltration rates not monotonically decreasing. In order to obtain the best results, a non-uniform order of the fractional derivative depending on the cumulative infiltration and the existence of available surface water is proposed for realistic cases. This allows significant improvement of previous published numerical results in the literature for several storm events in catchments where the infiltration process occurs.
Effects of tetracycline and ibuprofen on the relative abundance of microbial eukaryotic and bacterial populations in wastewater treatment
Authors: Abdelrahman H. , Islam G. M. , Gilbride K. A.
Published: April 2018

The activated sludge process in a wastewater treatment plant (WWTP) relies on the activity of microbes to reduce the organic and inorganic matter and produce effluent that is safe to discharge into receiving waters. This research examined the effects of the non-steroidal anti-inflammatory drug ibuprofen and the antibiotic tetracycline on the relative abundance and composition of eukaryotes and bacteria in the microbial population present in activated sludge from a WWTP. The current investigation was designed to observe the impact of these contaminants, at low (environmentally relevant concentrations) as well as high concentrations of the drugs. Using 16S and 18S rRNA gene primer sets and quantitative polymerase chain reaction, the abundance of each population was monitored as well as the relative ratio of the two populations under the various conditions. It was found that current environmentally relevant concentrations of ibuprofen (100 ng/mL) stimulated eukaryotic growth but higher concentrations (2,000 ng/mL, 100,000 ng/mL) reduced their numbers significantly especially in the presence of tetracycline. Finally using denaturing gradient gel electrophoresis, some of the more abundant eukaryotes were identified and it was noted that high ibuprofen and tetracycline concentrations favoured the abundance of some genera.
Advances in the Use of Anti-inflammatory Agents to Manage Chemotherapy-induced Oral and Gastrointestinal Mucositis
Authors: Mahendran Vaishnavi J. , Stringer Andrea M. , Semple Susan J. , Song Yunmei , Garg Sanjay
Published: April 2018

Mucositis is a side effect associated with the use of chemotherapy, and has a significant impact on the
quality of life. Mucositis, by definition, refers to the inflammation of the mucosa and occurs throughout the alimentary
tract from the mouth to anus. Nuclear Factor kappa B (NFκB) encompasses a family of transcription factors,
which upregulate pro-inflammatory cytokines. These are recognized as key targets in developing therapeutic interventions
for chemotherapy-induced mucositis, and cyclooxygenase (COX)-2 inhibition may also be beneficial in
reducing the severity and duration. This review focuses on the pathobiology of chemotherapy-induced oral and gastrointestinal
mucositis and recent research examining the role of agents with anti-inflammatory activity in treatment
and prevention of the condition. We consider agents in clinical use as well as some others under current investigation
including plant-derived and other natural medicines.
Cell-derived Exosomes as Promising Carriers for Drug Delivery and Targeted Therapy
Authors: Wang Xinyi , Zhang Haiyang , Yang Haiou , Bai Ming , Ning Tao , Li Shuang , Li Jialu , Deng Ting , Ying Guoguang , Ba Yi
Published: April 2018

Exosomes are small vesicles that are secreted by various types of cells, known to mediate
signal transduction between cells. During recent years, novel carriers for the delivery of targeted
drugs, chemotherapy drugs and RNAs are under development, which is believed to be beneficial for
patients. Considering issues of drug nano-formulations in bloodstream, such as nano-toxicity and
rapid clearance by mononuclear phagocyte system, exosomes derived from either patient’s cells or
bodyfluids, seem to be an optimal option. This review presents the current patterns of drug-loaded
into exosomes and discusses how exosomes were reconstructed for targeted therapy. Loading either
exosomes directly or their donor cells is an alternative, including incubation, electroporation, transfection
of exosomes or transfection, incubation, activation of the parent cells. To solve the low efficiency
of cargo loading into exosomes, protein loading via optically reversible protein-protein interaction
can realize a novel exosomal protein carrier. In addition, targeted therapeutics with exosomes
is achieved by three means, via adding targeting peptides into the surface of exosomes, by transferring
specific genes within exosomes into tumors to establish a therapeutic target and, lastly, by targeting
at exosomes containing tumor associated antigens. Nevertheless, purification and mass production
of exosomes need further exploration, as well as more approaches were applied to targeted
therapy. Therefore, exosomes could serve as an effective tool for drug delivery and targeted therapy.
Cancer Targeted Therapy Strategy: The Pathologist’s Perspectives
Authors: Alessandrini Lara , Perin Tiziana , Kadare Shahin , del Pup Lino , Memeo Lorenzo , Steffan Agostino , Colarossi Lorenzo , Berretta Massimiliano , De Paoli Paolo , Canzonieri Vincenzo
Published: April 2018

The effectiveness of new personalized treatment procedures in oncology is based on the
fact that certain tumors exhibit specific molecular features.

More in detail, neoplastic tissues of patients should display a specific biomarker, most often a specific
genetic alteration and/or under/overexpression of a definite protein, that could be the target of
its respective drug. Immunohistochemical and molecular analyses, which usually include examination
of nucleic acids from either tissues or fluids, are common tests to define the status of a tumor.

This review focuses on the pathologist’s role in carefully controlling pre- analytic procedures and
standard operating procedures that are a crucial prerequisite to reach reliable and reproducible results.
Six paradigmatic applications of targeted therapy, for which pathological diagnosis plays a
fundamental role, are summarized. Traditional and next-generation sequencing are also addressed
from the pathologist's perspective as well as the importance pathologists have in this shift to more
accurate definition of disease risk and prognostication of therapy response in the personalized medicine
era.
Optoelectronic Properties and Structural Modification of Conjugated Polymers Based on Benzodithiophene Groups
Authors: Wu Jieyun , Li Qing , Wang Wen , Chen Kaixin
Published: April 2018

Organic conjugated materials have shown attractive applications due to their good optoelectronic
properties, which enable them solution processing techniques in organic optoelectronic devices.
Many conjugated materials have been investigated in polymer solar cells and organic field-effect transistors.
Among those conjugated materials, Benzo[1,2-b:4,5-b′]dithiophene (BDT) is one of the most
employed fused-ring building groups for the synthesis of conjugated materials. The symmetric and planar
conjugated structure, tight and regular stacking of BDT can be expected to exhibit the excellent carrier
transfer for optoelectronics. In this review, we summarize the recent progress of BDT-based conjugated
polymers in optoelectronic devices. BDT-based conjugated materials are classified into onedimensional
(1D) and two-dimensional (2D) BDT-based conjugated polymers. Firstly, we introduce the
fundamental information of BDT-based conjugated materials and their application in optoelectronic devices.
Secondly, the design and synthesis of alkyl, alkoxy and aryl-substituted BDT-based conjugated
polymers are discussed, which enables the construction of one-dimensional and two-dimensional BDTbased
conjugated system. In the third part, the structure modification, energy level tuning and morphology
control and their influences on optoelectronic properties are discussed in detail to reveal the structure-
property relationship. Overall, we hope this review can be a good reference for the molecular design
of BDT-based semiconductor materials in optoelectronic devices.
Non-Gynecologic Causes of Adnexal/Pelvic Masses
Authors: Gainty Michelle L. , Jones Christina
Published: April 2018

Pelvic masses can pose a diagnostic dilemma with a broad differential to include
both gynecological and non-gynecologic etiologies. While the initial instinct may be to search for
gynecologic causes for the female patient, non-gynecologic etiologies must be considered as well.
The presentation can be similar amongst many different causes of pelvic masses and imaging is
generally required for further assessment to determine if the mass is intra- or extraperitoneal. The
etiology of adnexal masses covers several subspecialties: gynecology, urology, gastroenterology,
neurology, and oncology. For this reason, it is important for all to be aware of the differential
diagnosis for pelvic masses.
Molecular Characterization of Two Polysaccharides from Phellinus vaninii Ljup and their Cytotoxicity to Cancer Cell Lines
Authors: Jia Xuewei , Gao Mingqi , Li Mingzhe , Wu Yan , Zeng Ying , Xu Chunping
Published: April 2018

Background:

Phellinus vaninii, a medicinal basidiomycete fungus, is often confused with Phellinus
igniarius and Phellinus linteus. Polysaccharides extract from P. igniarius and P. linteus are reported to stimulate
humoral immunity and inhibit tumor growth However, available literature reviewed no information on the relationship
between bioactivities and structures of polysaccharides from the fruit body of P. vaninii.

Methods:

Two water-soluble polysaccharides (PV-W, PV-B) were isolated and purified from fruiting bodies of
P. vaninii by hot water and sodium hydroxide solution, respectively. The chemical structures of PV-W, PV-B
were analyzed by FT-IR, GC-MS analysis and 13C NMR spectra. And, their molecular conformations were
analyzed by viscosity method and SEC-MALLS-RI. Finally, their inhibition of cancer cells was investigated
using MTT assay.

Results:

The results illustrated that PV-W was a heteropolysaccharide, mainly composed of mannose, glucose,
arabinose and galactose. PV-B was a β-1, 3-D-glucan branched with β-1, 6-D-glucose. The results of viscometry
proved that PV-W and PV-B could be molecularly dispersed in water without aggregation. The results of SECMALLS-
RI indicated that the two polysaccharides had the similar Mw but different molecular conformation.
That is, PV-W existed as a stable globular shape, while PV-B presented a more expanded flexible random coils
conformation. MTT assay indicated that PV-B showed higher inhibition effect on HepG2 and HeLa cells than
PV-W in vitro.

Conclusion:

This work provided the important information of active components from P. vaninii and its potential
applications in the food and medicine industry.
A Case Series and Review of Bacillus Cereus Endocarditis from India
Authors: Gopinathan Anusha , Kumar Anil , Sen Amitabh C. , Sudha Srisruthy , Varma Praveen , GS Sunil , Eapen Malini , Dinesh Kavitha R.
Published: April 2018

Introduction:

Bacillus cereus is a gram positive bacilli found commonly in the soil and environment. It is a bacteria rarely associated with endocarditis.

Case History:

Intravenous drug abuse, presence of valvular defects, pacemakers, immunodeficiency are some of the known risk factors for B.cereus endocarditis. We present here a case series of two patients with B.cereus endocarditis along with a review of the literature.

Conclusion:

This is the first report of B.cereus endocarditis from India to the best of our knowledge.
Safety and Viability of Totally Tubeless Ambulatory Percutaneous Nephrolithotomy (APCNL) in the Fast Paced World
Authors: Hameed BM Zeeshan , Chawla Arun , Hegde Padmaraj , Odugoudar Avinash , Vasa Tirth
Published: April 2018

Background:

Percutaneous Nephrolithotomy (PCNL) is the gold standard for endoscopic management of large renal stones. Various modifications have been done to bring down the morbidity of this procedure. Ambulatory PCNL (APCNL) defines PCNL as day-care procedure, avoiding overnight hospital stay which is less than 24 hours. Totally tubeless makes faster recovery without the need for double J stent or nephrostomy tubes. This study aimed at exploring the feasibility and safety of APCNL in selective patients. It also aimed at improvising the procedure to facilitate early recovery and discharge of patients within 24 hrs.

Materials ands Methods:

In this study, 12 patients underwent APCNL under general anaesthesia with endotracheal intubation from April 2016 to March 2017. All the procedures were done by a single surgeon. The inclusion criteria were stone size of less than 2cm, without any co-morbidities, Computed Tomography (CT)/Retrograde Pyelogram(RGP) evidence of normal pyelocalyceal anatomy, patient staying within the radius of 15km, well informed patient. All patients underwent totally tubeless PCNL i.e. without nephrostomy, DJ stent and catheter. Skin infiltration was given with 0.25% Bupivacaine. Post operatively analgesia was given on demand (intramuscular Aceclofenac / oral Acetaminophen plus Tramadol). All patients were followed up after 2 weeks.

Results:

Twelve patients underwent prone PCNL. All patients had single puncture (10 lower calyx, 2 middle calyx), Amplatz size was less than 30F, size of the stone (1.3cm to 2cm) with a mean size- 1.7cm, saline used around 300ml. But, two patients were discharged after 36hrs and 48hrs due to pain. None of them returned to hospital with haematuria, pain or urinary tract infection.

Conclusion:

APCNL is a safe procedure in well informed selective patients. These are the patients with small burden of stone and staying close to the hospital. APCNL reduces the hospital stay, expenses and results in early return to work.
Chronic Osteomyelitis - Bacterial Flora, Antibiotic Sensitivity and Treatment Challenges
Authors: Jerzy Kuzma , Francis Hombhanje
Published: April 2018

Background:

Chronic osteomyelitis is a catastrophic sequel of delayed diagnosis of acute osteomyelitis.

Objectives:

The objectives of the study were to determine bacterial flora and antibiotic sensitivity, and to evaluate the outcome of an aggressive surgical approach to chronic osteomyelitis.

Methods:

This is a single surgeon, prospective cohort study on 30 consecutive patients with clinically and radiologically diagnosed chronic osteomyelitis presented to a hospital. We prospectively recorded demographic, clinical, radiological features, treatment protocol, microbiologic results of culture and sensitivity. The main treatment outcome measures were clinical signs of eradication of infection.

Results:

Microbiologic results showed that Gram-negative and mixed flora accounts for more than half of chronic osteomyelitis cases whileStaphylococcus aureuswas a dominating single pathogen (39%). We detected a high resistance rate to common antibiotics,e.g.83% ofS. aureusisolates were resistant to oxacillin (MRSA). The mean duration of bone infection was 4.2 years (3 months to 30 years) and the mean number of operations was 1.5 (1-5) . The mean follow-up was 15 months (12-18 months). Infection was eradicated in 95% (21 out of 22) treated by a single procedure and in all patients (n=8) by double procedure.

Conclusion:

Presented the high rate of MRSA strains is alarming and calls for updating of the antibiotic therapy guidelines in the country. Good results in treatment of chronic osteomyelitis can be achieved by a single-stage protocol including radical debridement combined with systemic and topical antibiotic.
A Survey on Men’s Awareness of Premenstrual Syndrome and Marital Satisfaction in Married Women in Tehran, Iran
Authors: Tavassoli Afsaneh , Ahmadian Maryam , Abu Samah Asnarulkhadi , Latiff Latiffah A. , Taheri Narges
Published: April 2018

Background:

The Premenstrual Syndrome (PMS) is a major clinical disorder with a number of temporary behavioral changes that is greatly affecting female population. Available information about PMS and marital satisfaction remains unclear, especially among women suffering from symptoms of PMS. The link between spousal supports has also been found to be related to marital satisfaction while no literature exists scrutinizing the effect of men’s awareness of PMS on marital satisfaction. This study intended to examine men’s awareness of PMS as a predictive factor for marital satisfaction among married women affected by PMS.

Aim:

To scrutinize the effect of men’s awareness of Premenstrual Syndrome (PMS) on marital satisfaction among married PMS-affected women.

Methods:

The sample for this cross-sectional survey comprised of 277 married 19-49 years old women who registered at gynecological outpatient clinics in Tehran, Iran. Data were collected following a multistage random cluster sampling approach in 2015. Main research variables were demographic data, an adapted Premenstrual Syndrome Scale (PMSS), Enrich Marital Satisfaction Scale as well as men’s awareness of the Premenstrual Syndrome.

Results:

This study found that the men’s awareness of PMS and having PMS symptoms were correlated to, and at times anticipated, the likelihood of marital satisfaction among PMS-affected women.

Conclusions:

The results can assist frontline health workers and health promotion strategists seeking to improve women’s health by providing visions into personal, relationship, and socio-cultural factors and offering consultation services for PMS issues in primary health care facilities in Iran.
KARASU KANAL SULARINDA BELİRLİ MİKROORGANİZMA TÜRLERİNİN ARAŞTIRILMASI
Authors: Çelebi Hakan
Published: April 2018

Bu
çalışmada, Aksaray ilinde bulunan Aksaray Üniversitesi yerleşkesi
yakınlarındaki Karasu sulama ve drenaj kanalının kirlilik açısından mikrobiyolojik
kalite seviyeleri (total ve fekal koliform vb.) mevsimsel olarak 2017 yılı
Temmuz, Nisan, Eylül ve Şubat aylarında drenaj kanalından yapılan
örneklemelerle incelenmiştir. Yüzey suyu örnekleri, kanalın 5 farklı
noktasından toplanmıştır. Bakteriyolojik tür düzeyinin belirlenmesinde membran
filtre metodu uygulanmış ve toplam koliform, fekal koliform, fekal streptokok
ve salmonella sayımları yapılmıştır. Yüzey suyunda toplam koliform bakteri
sayısı 92-302 KOB (koloni birimi)/100 mL, fekal koliform bakteri sayısı 16-225
KOB/100 mL, fekal streptokok bakteri 2-26 KOB/100 mL olarak bulunmuştur. Elde
edilen mikrobiyolojik analiz sonuçları Su Kirliliği Kontrol Yönetmeliği Kıta
içi Su Kaynakları Kalite Kriterleri 'ne göre değerlendirildiğinde; Karasu
sulama ve drenaj kanalı’nın II. sınıf su kalitesinde, az kirlenmiş su olduğu
tespit edilmiştir.
Health Care Providers’ Profiles and Evaluations of a Statewide Online Education Program for Dissemination of Clinical Evidence on HIV, Hepatitis C Virus, and Sexually Transmitted Disease: Cross-Sectional Study (Preprint)
Authors: Wang Dongwen , Abrams Meredith
Published: April 2018

BACKGROUND

Timely and effective dissemination of the latest clinical evidence to health care providers is essential for translating biomedical research into routine patient care. Online platforms offer unique opportunities for dissemination of medical knowledge.

OBJECTIVE

In this study, we report the profiles of health care providers participating in the New York State HIV-HCV-STD Clinical Education Initiative online program and their evaluations of the online continuing professional development courses.

METHODS

We compiled professional and personal background information of the clinicians who completed at least one online course. We collected their self-reported program evaluation data with regard to the course content, format, knowledge increase, and impact on clinical practice.

RESULTS

We recorded a total of 4363 completions of 88 online courses by 1976 unique clinicians during a 12-month study period. The clinicians’ background was diverse in terms of demographics, education levels, professional disciplines, practice years, employment settings, caseloads, and clinical services. The evaluation of online courses was very positive (usefulness/relevance, 91.08%; easy comprehension, 89.09%; knowledgeable trainer, 92.00%; appropriate format, 84.35%; knowledge increase, 48.52%; intention to use knowledge, 85.26%; and plan to change practice, 21.98%). Comparison with the reference data indicated that the online program successfully reached out to the primary care communities. Both the younger generation and the senior health care providers were attracted to the online program. High-quality multimedia resources, flexibility of access, ease of use, and provision of continuing professional development credits contributed to the initial success of this online clinical education program.

CONCLUSIONS

We have successfully characterized a diverse group of clinicians participating in a statewide online continuing professional development program. The evaluation has shown effective use of online resources to disseminate clinical evidence on HIV, hepatitis C virus, and sexually transmitted disease to primary care clinicians.
Public Attitudes Toward Guided Internet-Based Therapies: Web-Based Survey Study (Preprint)
Authors: Apolinário-Hagen Jennifer , Harrer Mathias , Kählke Fanny , Fritsche Lara , Salewski Christel , Ebert David Daniel
Published: April 2018

BACKGROUND

Internet interventions have been proposed to improve the accessibility and use of evidence-based psychological treatments. However, little is known about attitudes toward such treatments, which can be an important barrier to their use.

OBJECTIVE

This study aimed to (1) determine attitudes toward guided internet interventions, (2) assess its acceptability compared with other internet-based formats, and (3) explore predictors of acceptance.

METHODS

A convenience-sample Web-based survey (N=646) assessed attitudes toward guided internet therapies (ie, perceived usefulness and helpfulness, and advantage relative to face-to-face therapy), preferences for delivery modes (ie, e-preference: guided internet interventions, unguided internet interventions, or videoconferencing psychotherapy), and potential predictors of attitudes and preferences: sociodemographics, help-seeking–related variables, attachment style, and perceived stress.

RESULTS

Although most participants perceived internet interventions as useful or helpful (426/646, 65.9%), a few indicated their advantage relative to face-to-face therapy (56/646, 8.7%). Most participants preferred guided internet interventions (252/646, 39.0%) over videoconferencing psychotherapy (147/646, 22.8%), unguided internet interventions (124/646, 19.2%), and not using internet interventions (121/646, 18.8%; missing data: 1/646, 0.2%). Attachment avoidance and stress were related to e-preference (all P<.05). Moreover, preference for therapist-guided internet interventions was higher for individuals who were aware of internet-based treatment (χ26=12.8; P=.046).

CONCLUSIONS

Participants assessed therapist-guided internet interventions as helpful, but not equivalent to face-to-face therapies. The vast majority (523/646, 81.0%) of the participants were potentially willing to use internet-based approaches. In lieu of providing patients with only one specific low-intensity treatment, implementation concepts should offer several options, including guided internet interventions, but not limited to them. Conversely, our results also indicate that efforts should focus on increasing public knowledge about internet interventions, including information about their effectiveness, to promote acceptance and uptake.
Formação docente e novas tecnologias: repensando a teoria e a prática
Authors: Dvorak Patrícia Eliza , Araújo Izabel Cristina de
Published: April 2018

RESUMO Analisar a formação docente requer uma visão ampla de suas características e de sua realidade. A evolução tecnológica possibilitou o repensar da atuação docente em outras perspectivas bem como sua relação com as diversas características humanas e sociais. A possibilidade de quebrar velhos paradigmas revela novos caminhos necessários para a inovação pedagógica e tecnológica em sala de aula. Este artigo apresenta um estudo de caso que tem o objetivo de contribuir para a análise acerca das necessidades de formação para a utilização das novas tecnologias observando os aspectos humanos e sociais aplicados ao contexto da realidade do docente em formação. Para o estudo foram selecionados, de forma aleatória, programas dos cursos de Pedagogia disponíveis na internet. Palavras-chave: Formação docente.  Novas tecnologias. Formação inicial. Formação continuada. ABSTRACT The analysis of teacher training requires an overview of its characteristics and its reality. The technological development made possible the exercise of reconsidering the teacher role under other perspectives as well as how it relates to various human and social characteristics. The possibility of breaking established paradigms shows new paths that are necessary to the pedagogical innovation within the classroom. The following article presents a case study that aims to contribute for the analysis of the need of training courses to acquaint teachers with the use of new technologies. Such analysis should consider social and human aspects applied to the background of the teacher who is in training. The study considered, randomly, the syllabus of Pedagogy courses available on the web.   Key words: Teacher training. New Technologies. Early Training. Ongoing Training.   RESUMEN Analizar la formación del profesor requiere una visión amplia de su realidad y sus características. El progreso tecnológico ha permitido el replanteo de la actuación del profesor en otras perspectivas, así como su relación con las diversas características humanas y sociales. La posibilidad de romper viejos paradigmas revela nuevas formas necesarias para la innovación pedagógica y tecnológica en el aula. Este artículo presenta un estudio de caso que pretende contribuir al análisis de las necesidades de formación para el uso de las nuevas tecnologías observando los aspectos humanos y sociales aplicados al contexto de la realidad del docente en formación. Para el estudio se seleccionaron, al azar, programas de los cursos de Pedagogía disponibles en internet. Palabras clave: Formación docente.  Nuevas tecnologías. Formación inicial. Educación continua. DOI: http://dx.doi.org/10.22169/revint.v11i23.885
Literatura digital em sala de aula: do contar ao miniconto
Authors: Pereira Ânderson Martins , Lazzaris Fabiane
Published: April 2018

RESUMO O presente artigo busca discutir a implementação da literatura digital em aula a partir de um estudo de caso que visa o trabalho com o miniconto no Twitter, questionando-se acerca da produção de textos autorais pelos alunos e avaliação de tais experiências. Para tal, este trabalho utiliza-se especialmente das contribuições de Scholes (2011), Howitt-Dring (2011), Santaella (2010) e McLuhan (1971). Esta proposta justifica-se por contribuir com os estudos acerca da literatura digital, os quais têm se destacado nas últimas décadas e tornado disponíveis novas ferramentas para a vivência da arte em sala de aula. Palavras-chave: Literatura digital; Miniconto; Twitter.   ABSTRACT The present paper aims to discuss the implementation of digital literature in the classroom from a study of case that worked with short fiction on Twitter, eliciting the elements that are in the production of authorial texts made by the students and how to evaluate such experiences.  For such purpose, this article is based on the contributions of Scholes (2011), Howitt-Dring (2011), Santaella (2010) and McLuhan (1971). This paper is justified to contribute with the studies about digital literature, which have stood out in recent decades and have made available new tools for an artistic living in the classroom.   Keywords: digital literature; Short fiction, Twitter.   RESUMEN El presente artículo busca discutir la implementación da literatura digital en el aula desde de un estudio de caso que busca desarrollar un trabajo con la producción de minicuentos en el Twitter, cuestionando tras la producción de textos autorales por los alumnos y la evaluación de tales experiencias. Para tal, este trabajo está basado especialmente en los aportes teóricos de Scholes (2011), Howitt-Dring (2011), Santaella (2010) e McLuhan (1971). Esta propuesta se justifica por contribuir con los estudios respeto a la literatura digital, los quales han logrado destaque en las últimas décadas, ofreciendo nuevas herramientas hacía la vivencia del arte en el salón de clase. Palabras-clave: Literatura digital; Minicuento; Twitter. DOI: http://dx.doi.org/10.22169/revint.v11i23.930
El premio Nobel de Química 2017: microscopía crio-electrónica
Authors: Bedolla Carlos Amador
Published: April 2018

El premio Nobel de Química 2017 se otorgó a tres científicos que, durante casi cuarenta años, han resuelto complicadísimos problemas físicos, químicos, matemáticos y computacionales para lograr que la microscopía electrónica sirva para detectar la estructura tridimensional de complejos bioquímicos, entre los que destacan las proteínas. Este intricado método analítico permite, adicionalmente, estudiar el movimiento molecular que es fundamental para la función bioquímica de las proteínas.
Aprendizaje basado en problemas: ¿en qué tiempo se descompone la leche pasteurizada a temperatura ambiente?
Authors: Obaya Adolfo , Vargas Rodríguez Guadalupe Iveth , Lima-Vargas Alvaro Enrique , Vargas-Rodríguez Yolanda Marina
Published: April 2018

En los cursos de cinética química de licenciatura, se estudia la rapidez de las reacciones químicas, así como los efectos de temperatura en la rapidez de reacción, a través de ejercicios que utilizan métodos matemáticos como integración de ecuaciones de rapidez y funciones que se ajustan mediante regresión lineal. Con estos ejercicios, los alumnos desarrollan el tratamiento matemático de los datos sin lograr aprendizajes significativos. Es por ello, que surge la necesidad de crear ejercicios como “verdaderos problemas”, que tengan que ver con su vida cotidiana, esto es, aplicar el Aprendizaje Basado en Problemas (ABP). Se presenta el problema ¿Cuánto tiempo (en horas) se conserva la leche pasteurizada a temperatura ambiente?, a estudiantes de Fisicoquímica V (Cinética Química), de la carrera de Química de la FES Cuautitlán UNAM. A partir del cuestionamiento, surgieron una serie de preguntas, respuestas y acciones por parte de los estudiantes y del profesor. Con el modelo de primer orden, la ecuación de Arrhenius y el tratamiento matemático adecuado los estudiantes determinaron el número de horas en que se conserva la leche a temperatura ambiente. Los resultados mostraron que después de aplicar el ABP, los estudiantes comprendieron el efecto de la temperatura en la rapidez de la reacción. Esta estrategia, permitió estudiar el efecto de la temperatura en la rapidez de una reacción de una forma didáctica para lograr aprendizajes significativos, por lo que puede ser utilizado en los cursos de cinética química con el fin de incrementar el rendimiento académico.
the effect of problem based learning mode and cognitive style toward students’ mathematic achievement, there is a correlation between cognitive style toward students’ mathematic achievement the interaction effect between learning mode and students’ cognit
Authors: Ikhlas Al
Published: April 2018

Abstrak

 

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran berbasis masalah dan gaya kognitif terhadap hasil belajar matematika siswa, korelasi  antara gaya kognitif terhadap hasil belajar matematika siswa, dan pengaruh interaksi antara penggunaan model pembelajaran dan gaya kognitif siswa terhadap hasil belajar matematika siswa di kelas VIII (Delapan) SMP Negeri 7 Kerinci tahun pelajaran 2016/2017. Penelitian ini dilakukan dengan metode penelitian eksperimen semu dengan menerapkan desain faktorial 2 × 2. Populasi penelitian adalah siswa SMP Negeri 7 Kerinci Kelas VIII Semeseter genap tahun pelajaran 2016/2017. Sampel penelitian terdiri dari kelas eksperimen berjumlah 32 orang siswa dan kelas kontrol berjumlah 31 orang siswa. Pengumpulan data dilakukan menggunakan dua macam instrumen yakni intrumen Group Embedded Figures Test (GEFT) untuk mengukur gaya kognitif siswa dan instrumen tes hasil belajar matematika siswa dalam bentuk essay. Hasil analisis data dan uji statistik menunjukkan bahwa model pembelajaran berbasis masalah  dan  gaya  kognitif  berpengaruh terhadap hasil belajar matematika, terdapat  korelasi  antara  gaya kognitif terhadap hasil belajar matematika, tidak terdapat interaksi antara model pembelajaran dan gaya kognitif terhadap hasil belajar matematika  siswa. Berdasarkan hasil penelitian tersebut disarankan kepada guru, khususnya guru matematika agar penerapan model pembelajaran berbasis masalah  dikembangkan sebagai satu inovasi dalam proses belajar mengajar.
Anomalías congénitas del riñón y del tracto urinario en niños con síndrome de Down
Authors: Mora-Bautista Víctor Manuel
Published: April 2018

Las anomalías del riñón y el tracto urinario hacen parte de las anomalías congénitas relacionadas con el síndrome de Down. No existen recomendaciones específicas. Para el presente estudio, se hizo una revisión por palabras clave en bases de datos (Pubmed, Science Direct, Ovid, Google académico, UpToDate). Se encontró que, en niños con síndrome de Down, las enfermedades congénitas del riñón y el tracto urinario abarcan glomerulonefritis, agenesia renal, microquistes, riñones ectópicos, hidronefrosis, hidrouréter, valvas uretrales posteriores, obstrucción de la uretra anterior e hipospadias. Con respecto a los procesos diagnósticos, sería razonable realizar una ecografía renal durante la primera semana de vida. Adicionalmente, la uretrocistografía sería útil solo en casos seleccionados. Si hay un historial de incontinencia urinaria o de infecciones urinarias de repetición; o se detecta un reflujo vesicoureteral, o caída de la tasa de filtración glomerular estimada, debería considerarse la existencia de una disfunción vesical asociada y podría ser pertinente una evaluación urológica (uroflujometría o urodinamia). Sería recomendable hacer un seguimiento clínico anual de la función renal.
Hipertensión renovascular secundaria a hipoplasia congénita de arterias renales en un paciente adulto Joven. A propósito de un caso
Authors: Ñañez Paz Julián Darío , Orozco Burbano Juan David , Hernández Duque Natalia
Published: April 2018

La hipotrofia de aspecto tubular de las arterias renales, constituye una rara entidad clínica que se asocia a la aparición de hipertensión renovascular. Su enfoque diagnóstico es complejo y exige la disponibilidad de angiografía para poder determinar las características propias del contorno de la vasculatura renal. El siguiente caso clínico ejemplifica el proceso diagnóstico de un paciente con esta particular situación.
Resultados clínicos en receptores de trasplante renal posterior a la conversión a ImTOR
Authors: Mesa Ramirez Liliana , Gómez Vega Juan C. , Pino - Escobar Jessica , Rivera Lina M , Manzi -Tarapues Eliana , Posada - Chavez Juan G. , Schweineberg - López Johanna , Duran - Rebolledo Carlos E. , Villegas - Otálora Jorge I. , Serrano Ardila Oscar J. , Caicedo-Rusca Luis A.
Published: April 2018

Introducción: los ImTOR, sirolimus y everolimus son una alternativa de inmunosupresión en personas que han recibido transplantes renales. En este artículo, se describe la experiencia de pacientes que han experimentado una conversión a ImTOR, y a los que se les ha hecho un seguimiento por más de cinco años.Materiales y métodos: se incluyeron pacientes con transplantes renales desde 1995 hasta 2013, quienes tuvieron indicación de suspensión del inhibidor de calcineurina (ICN) después del tercer mes posterior al trasplante. Todos los pacientes fueron sometidos a biopsia renal antes de la administración de ImTOR. Ningún paciente tuvo diagnóstico de nefropatía crónica, IFTA >40 % o proteinuria >350 mg/24h. Se elaboró un análisis descriptivo para todas las variables. Para estudiar la supervivencia del paciente y del injerto, y la incidencia de rechazo agudo, se usó el método de Kaplan-Meier.Resultados: de 1273 trasplantes renales, la conversión de ICN a ImTOR se realizó en 166 casos (13 %). Al 78 % (n=129) se le administró sirolimus. El 13 % de los pacientes perdió la función del injerto y 7 pacientes (4,2 %) fallecieron. En el 37 % de los casos, se retiró el ImTOR. La principal causa de retiro fue el hallazgo de proteinuria patológica. La incidencia de rechazo agudo después del cambio a ImTOR fue de 9,6 %. La supervivencia del injerto tras uno y cinco años fue de 96,6 % y 83,5 %, respectivamente; y la supervivencia del paciente a uno y cinco años fue de 98 % y 97 %, respectivamente.Conclusiones: el uso de inhibidores ImTOR parece ser seguro en este grupo de pacientes trasplantados, pues hubo una baja tasa de rechazo y buena supervivencia del injerto.
Late adolescent pregnancies, maternal and fetal outcomes
Authors: KAYA Aşkı Ellibeş , BAŞBUĞ Alper , SÖNMEZ Cemil İşık , BARUT Ceren , ŞENGÜN Yunus , ÇAĞLAR Mete
Published: April 2018

Introduction: In our study, we aimed to review the maternal and
fetal outcomes by comparing adolescent and reproductive age pregnancies in
Düzce University Training and Research Hospital.Methods: A retrospective study conducted with 183 patients
out of 3223 who gave birth at Düzce University Research and Practice Hospital
Obstetrics and Gynecology Clinic, between 01.01.2015 and 31.05.2017. SPSS 21
program for statistical evaluation were used, a value of p <0.05 was
considered statistically significant.Results: The total complication rate of adolescent age
pregnancies was higher than control group (p=0.03). No significant result was
found in subgroup analysis. As educational status increases, adolescent
pregnancy rates decrease (p=0.01).

Conclusion: Adolescent pregnancies increase maternal and fetal
complications. Adolescent pregnancies should be prevented, social support,
training and regular follow-up should be done to improve pregnancy outcomes.
Clinical scoring for distinction of bacterial and viral upper respiratory tract infections of children
Authors: ARSLAN Mesut , ELBİR ŞAHİN Ayşegül , GÜLSEVER Osman , ŞANLI GÜNEŞ Hatice , ASLANER ALDEMİR Betül , DURAN Fatih , ŞAHİN İrfan Oğuz
Published: April 2018

Introduction: Upper
respiratory tract infections (URTI) are
the most common infections of childhood. 
The purpose of our study is to develop a clinical scoring method to
distinguish viral and bacterial infections in the patients who were diagnosed
with URTI. Methods: This study was conducted in pediatric 220 patients
with URTI whose ages were between 5 and 15. The previous studies about clinical scoring of
bacterial and nonbacterial URTI were reviewed to determine signs and symptoms
to evaluate in our study. These signs,
symptoms and throat swab culture results of the patients were
recorded. Results: Throat swab culture were positive at 93 patients
(42%). According to this clinic scoring system; fever, painful anterior
servical lymphadenopathy, lack of cough, tonsillar hypertrophy were found to be
statistically significant in terms of predicting bacterial infections.
Dysphagia, abdominal pain, headache, lack of conjunctivitis, the absence of
hoarseness and the absence of diarrhea were found to be statistically
insignificant.

Conclusion: Acording to total score – culture relationship,
total score 7 and higher could be considered significant. As a result of our
study, we could not develop an effective scoring due to the high number of
parameters, low sensitivity and specifity.
La investigación en el currículo de las carreras de grado
Authors: Saenz FC
Published: April 2018

Hoy, el mundo moderno no solo exige competitividad, sino también la capacidad de adaptarse a los cambios sociales, tecnológicos y, fundamentalmente, participar en la generación de nuevo conocimiento. El modelo educativo tradicional en Argentina ha enfocado la educación médica hacia el desarrollo del conocimiento médico científico, destrezas y actitudes, poniendo énfasis a la educación clínica-asistencial y dejando relegada la formación en el terreno de la investigación clínica y ciencias básicas.
Correlación diagnóstica entre fibronasolaringoscopía y video endoscopia digestiva alta en pacientes con reflujo gastroesofágico y reflujo faringolaríngeo
Authors: Torres López D , Cortadi D , Romero Orellano F
Published: April 2018

El reflujo faringolaríngeo. Se origina por el flujo retrógrado de contenido gástrico hacia la faringe, pero existen factores, capaces de perpetuarlo: disfunción del esfínter esofágico, tiempo de exposición y sensibilidad del tejido al material refluido, estos elementos permiten considerar al reflujo faringolaríngeo como una entidad diferente del reflujo gastroesofágico.
R-Medic. Un programa de análisis estadísticos sencillo e intuitivo
Authors: Mangeaud A , Panigo DE
Published: April 2018

Se presenta el “soft” estadístico R-Medic, un programa que se utiliza directamente en la web sin necesidad de instalarlo o descargarlo en computadoras o dispositivos móviles. El programa posee cinco prestaciones generales: realiza un control que permite evaluar si las variables de la base de datos están correctamente cargadas, realiza tablas, gráficos, pruebas estadísticas y presenta herramientas didácticas de distribución de variables. Su uso es intuitivo ya que se debe definir si se poseen una o dos variables a estudiar y el “soft” propone los posibles análisis a realizar. Ofrece las pruebas de supuestos y responde con los estadísticos, valor p e interpretaciones de los resultados.