bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Environmental Stresses on Physiophytochemical Responses and Expressional Profiling Analysis of Flavone C-Glycoside-Associated Genes in Three Bamboo Species
Authors: Maksup Sarunyaporn , Janejobkhet Juthathip , Obsuwan Kullanart , Kasemsukphaisan Sirinta , Hemsart Siwaporn
Published: December 2024

Bamboo, valued for its sustainability and versatility, holds potential in various domains, including food and medicine, due to its abundance of antioxidant compounds such as flavone C-glycosides (FCG) found in bamboo leaf extracts. However, the effects of environmental stress on bamboo growth, phytochemical synthesis, and the genetic regulation of FCG biosynthesis remain unclear. This study investigated the response mechanisms of 3 bamboo genotypes (Pai Sang-Mon, Pai-Liang, and Pai Khao-Lam) under different environmental stresses: Acidity (pH 4.0), heavy metal zinc (200 µM ZnSO4·7H2O), salinity (100 mM NaCl), and water deficit stress over 0, 1, 2, 4, and 8 days. The results indicated that water deficit stress had the most significant impact on growth and photosynthesis, with Pai Khao-Lam and Pai Sang-Mon exhibiting greater drought tolerance than Pai-Liang. Reversed-phase high-performance liquid chromatography (RP-HPLC) analysis revealed diverse responses in phytochemical content. Pai Sang-Mon showed increased caffeic acid and apigenin under salt stress, while Pai-Liang exhibited decreased phytochemical content under acid, zinc, and water deficit stresses. In contrast, Pai Khao-Lam showed elevated p-coumaric acid, chlorogenic acid and vitexin levels under multiple stresses, indicating robust antioxidant capabilities. Gene expression analysis using quantitative real-time PCR indicated differential gene responses among the bamboo genotypes. Pai Sang-Mon showed reduced vitexin levels correlating with decreased expression of the C-glycosyltransferase (CGT1) gene. Pai Khao-Lam exhibited increased expression of the flavanone 2-hydroxylase (F2H) and CGT1 genes under water deficit stress, suggesting a molecular response to maintain cellular homeostasis through phytochemical accumulation. In contrast, Pai-Liang showed increased expression of the sucrose nonfermenting 1-related protein kinase 1 (SnRK1) gene under short-term salt stress, indicating the sensitivity to osmotic stresses. These findings highlight the complex relationship between gene regulation, phytochemical accumulation, and stress tolerance in bamboo, offering valuable insights for breeding bamboo with enhanced stress tolerance and optimizing environmental conditions to maximize phytochemical production in bamboo leaf extracts.
HIGHLIGHTS

Water deficit stress significantly impacts bamboo growth and photosynthesis.
Greater drought tolerance in Pai Khao-Lam and Pai Sang-Mon than in Pai-Liang.
Pai Khao-Lam shows increased chlorogenic and p-coumaric acid under multiple stresses.
The regulation of CGT1, F2H, and SnRK1 genes differs in bamboo genotypes under stress.

GRAPHICAL ABSTRACT
REVISITANDO NOSSOS CLÁSSICOS: "Ecologia e Pensamento Revolucionário"
Authors: Zilio Rafael
Published: December 2024

Tradução do ensaio "Ecologia e Pensamento Revolucionário", de Murray Bookchin.
Tradutor: Rafael Zilio
Türkiye’nin Sürdürülebilir Kalkınma Hedefleri’ne Yönelik Uluslararası İşbirliği Faaliyetlerinde Bilim Diplomasisinin Yeri ve Önemi: TİKA'nın Afrika Faaliyetlerinden Örnekler
Authors: Nurdun Rahman
Published: December 2024

Bilim diplomasisi, bilimsel araştırmaları küresel politika çözümleriyle birleştirerek Sürdürülebilir Kalkınma Hedefleri'ne (SKH'ler) ulaşmada kritik bir rol oynamaktadır. Bu çalışmanın amacı, Türkiye'nin bilim diplomasisi uygulamalarını Türk İşbirliği ve Koordinasyon Ajansı’nın (TİKA) bazı Afrika ülkelerinde SKH’lere ulaşmaya yönelik çabalara destek kapsamında yürüttüğü kalkınma işbirliği faaliyetler üzerinden değerlendirmektir. TİKA'nın tarım projeleri, sürdürülebilir tarım uygulamalarını desteklemek amacıyla eğitim ve kaynak sağlayarak gıda güvenliğini artırmayı ve iklim değişikliğine karşı dayanıklılığı güçlendirmeyi hedeflemektedir. Bu çabalar, partner ülkelerde tarımsal verimliliği ve sürdürülebilirliği geliştirmeyi amaçlamakta olup, SKH 2 (Açlıkla Mücadele) ve SKH 13 (İklim Eylemi) ile uyumludur. Buna paralel olarak, TİKA’nın kurduğu mesleki eğitim merkezleri, topluluklara gerekli becerileri kazandırarak ekonomik büyümeyi teşvik etmekte ve iş fırsatları oluşturmaktadır. Bu eğitim programları, istihdamı artırarak ekonomik kalkınmaya katkı sağlamakta olup SKH 4 (Nitelikli Eğitim) ile SKH 8 (İnsana Yakışır İş ve Ekonomik Büyüme) hedefleriyle uyumludur. Bunları yanı sıra CEZERI-LAB’ları, bilim ve teknoloji alanındaki yenilikleri destekleyerek bilim diplomasisinin bir aracı olarak etkin şekilde kullanılmaktadır. Bu örnekler, kalkınma işbirliği ve bilim diplomasisinin etkileşimini ve bu etkileşimin SKH’leri gerçekleştirmeye yönelik küresel işbirliği faaliyetlerindeki önemini anlamak açısından önem arz etmektedir. Bu noktada çalışmamız, TİKA'nın bilim diplomasisi girişimlerinin somut etkilerini ortaya koyan vaka çalışmaları sunarak, bu projelerin SKH’lere nasıl katkıda bulunduğunu somut olarak göstermeyi hedeflenmektedir. Türkiye’nin TİKA aracılığıyla yürüttüğü bilim diplomasisi stratejisi, SKH’lere ulaşma çabalarında yürüttüğü kalkınma işbirliği faaliyetlerinin etkinliği açısından değerli bilgiler sunmaktadır.
Effectiveness of Sanitization Assessment by ATP Bioluminescence Detection System as a Complementary Method in Vivarium: A five-year status report
Authors: Devan R K Shakthi , Banu Mudaseera , Mallikarjuna Yogisha , P Shonima
Published: December 2024

Sanitization is an important activity performed in the laboratory animal facilities and periodical  assessment of sanitization provides confidence in surface cleanliness as well as health status of  animals in the vivarium. The primary objective was to evaluate routine disinfection and/or sanitization  practices upon verifying the adenosine triphosphate (ATP) bioluminescence method, which further  expressed as relative light units (RLU), a relatively easy and rapid method to interpret results within a  minute after the swab sampling performed on any surface. A five-year data compilation showed that  RLU values were within the in-house acceptable limits of animal rooms sampled from racks, isolators,  doors, trolleys, cage changing stations, tables, walls and cage accessories. However, some of the  materials such as racks and trolleys of high-traffic areas showed a significant increase in RLU values  due to organic matters that might be present on the equipment surfaces but recorded values were well  within the limits set by the facility. Additionally, contact plates were also used as confirmatory method  to evaluate microbial monitoring in animal rooms including cage accessories and further historical  values of RLU provided confidence to increase monthly contact plate sampling interval to a quarterly  basis and followed as per the schedule. Moreover, representative samples from incoming animals were  screened by microbial monitoring at regular intervals during the quarantine period and active sentinel  samples also screened for serology or PCR as part of comprehensive health monitoring program. In  conclusion, ATP method can be used to assess the real-time effectiveness of sanitization practices in  vivarium as it provides immediate feedback to animal care personnel that enables corrective actions;  hence the ATP bioluminescence is continued as one of the complementary methods at our laboratory  animal facility.
An insight and spatiotemporal analysis of the establishments involved in animal experiments in India
Authors: Krishnamoorthy P , Lakshmi H K
Published: December 2024

The establishments registered with the Committee for Control and Supervision of Experiments on  Animals (CCSEA), Good Laboratory Practice (GLP) certified, and AAALACInternational accredited were  obtained from online sources. The spatial distribution map of the establishments was prepared by  collecting latitude and longitude using Quantum Geographic Information System (QGIS) version 3.4  Madeira, an open-source software. The establishments registered with CCSEA, GLP certified, and  AAALAC accredited in India were 1583, 52, and 28, respectively and the period was confined to 1999 to  2023. Based on the organization nature, more private establishments were registered with CCSEA [1132], GLP [48], and AAALAC International [28] than Government establishments. The type of animals  used for animal experiments by the establishments revealed that the small animals were in CCSEA [91.5%], GLP [68%], and AAALAC International [71%] compared to large animals. Based on the  breeding purpose, establishments carrying in-house breeding were in CCSEA [79%], GLP [71%], and  AAALAC International [70%]. The purpose of registration showed a higher number of establishments  with educational purposes for CCSEA, and contract establishments for GLP and AAALAC International.  The state-wise analysis revealed a higher number of establishments registered with CCSEA, GLP  certified, and AAALAC International accredited were in Maharashtra, Telangana, and Maharashtra,  respectively. The goals of CCSEA, GLP, and AAALACInternational are to enhance the animal well-being and quality of animal experiments, improve laboratory animal facility standards, and enhance biological  research on humans and animals. Further, there is a need for a good monitoring system for the  establishments involved in animal experiments in India.
Religion-Based Perspective and Influences on Use of Animals in Research
Authors: Karunarathna Ureshani , Yapa Piumika , Menike A A I S , Ganesh Lakshy , Ganesh KSV Angu Bala , Thilakarathna Amandi , Gunatilake Mangala , Singh Vijay Pal , Md Isa Muhammad Lokman , Poosala Suresh , Baumans Vera
Published: December 2024

All religions are concerned with the care and welfare of animals, paying respect to the animals. Beliefs and  attitudes towards animals that are based on religious and cultural perspectives play an important role in  human-animal relationships. Christian attitudes have been impacted by Western philosophical  consideration of human-animal relationships, whereas Eastern religions (Hinduism, Buddhism, and Islam)  and their teachings impose varying values on the existence of animals. Even though their justifications affect  the views of individuals and their feelings toward animal testing, scientists continue to employ animals in  their research. Even though it is impossible to underestimate the worth of a life, this article describes the  religious perspectives on animal existence and harming to animals.
Heteropteran Bugs of the Order Hemiptera - A Review Article
Authors: Pravin B. Kale  , Chandrakant V. Sirsat
Published: December 2024

Various diversity research papers &surveys on the order hemiptera-heteroptera from different regions have been reported by different researchers. This review article, considered more than 382 articles published from 1902 to 2024 (122 years) from which only 58 were selected for the analysis based on the current objectives. The plant bugs (hemiptera: Heteroptera) contains general and specific feeders on plants and on animals,some feeding on vertebrate blood has evolved at least three times. Many Heteropterans (especially infraorders pentatomidae) prefer the reproductive parts of plants, flowers, ovules, ovaries, ripening and ripened seeds. Other (Miridae and Tingidae: infraorder Cimicomorpha) damage nonreproductive parts of plant, causing the plant to mobilize nitrogen to make repairs. Heteropterans thus injure plants directly, by destroying or reducing the fecundity and fertility of reproductive structure desired also by humans or by forcing the plant into under taking energetically costly repairs. Heteropterans thrust their styles into plant tissue, between cells. Many Heteropterans are predaceous. Heteropterans causes various physiological and biochemical changes in the tissue of host plants. (Schaefer and Panizzi 2000)1. People around the world are using insects as food and for therapeutic purposes. Edible insects contain various metabolites. There are reports on the presence of various primary and secondary metabolites like steroids, triterpenoids, cardiac glycosides, anthraquinones, favonoids, tannins, alkaloids, amino acids and reducing sugars in methanolic extract of Henicuswhellani (crickets) and Macrotermesfacilger (termites).
The Croatian War of Independence (1991–1995) in medical literature
Authors: Sapunar Damir , Matijaca Danira , Shmatkova Mariia , Gambiroža Leonarda , Orlandić Irma Nina , Marušić Matko , Marušić Ana
Published: December 2024

Aim: To evaluate the scientometric characteristics of ar-ticles related to the Croatian War of Independence (1991–1995) published in the Croatian Medical Journal (CMJ) by analyzing citation trends and identifying key contributions to medical and societal research during and after the War (1991–2024).Methods: We manually identified war-related articles from the CMJ website and screened them based on their titles and abstracts. We then retrieved their citation data using the Clarivate Web of Science and analyzed their citation met-rics, journal impact factors (IF), and quartiles. Articles were categorized by research focus, publication type, and citation frequency.Results: CMJ published 301 war-related articles, most of which appeared in 1992. They acquired 2,544 citations, pri-marily in Web of Science-indexed journals, with 68.9% of citations occurring in international journals. The majority of citations were from journals in the third quartile (32.4%), with only 2.3% occurring in top-tier journals (IF > 10). Key re-search topics included the psychological impacts of war (e.g., PTSD), public health, and healthcare system reorganization. Articles on secondary traumatic stress in war veterans’ fam-ilies, systematic rape during the war, and advancements in forensic DNA analysis were among the most cited articles, with individual citation counts of 78, 76, and 73, respectively.Conclusion: CMJ played an important role in documenting the medical and societal impacts of the War of Independence, advancing knowledge on psychological trauma, healthcare organization during the war, and human rights issues. Despite modest representation in high-impact journals, the articles made visible contributions to global discussions on war-related health research. CMJ’s innovative editorial pol-icies, including its author-supportive pre-review process, fostered excellent research during and after the war. This analysis emphasizes the importance of CMJ in addressing the multifaceted consequences of the war, both as a plat-form for scholarly collaboration and as a repository of his-torical and educational value.
RESPONSABILIDAD SOCIAL, INNOVACIÓN Y SOSTENIBILIDAD PARA LA TRANSFORMACIÓN EMPRESARIAL
Authors: Roland Alvarado Arbildo Gilbert , Henry Ruiz Vásquez Hugo , Arturo Jesús Castillo Canani Víctor , Pinedo Vda. de Echevarria Alicia
Published: December 2024

Esta investigación explora el impacto de la responsabilidad social y la innovación en la transformación empresarial en un entorno competitivo y en constante
cambio. Se utilizó la metodología Prisma para revisar artículos publicados entre 2019 y noviembre de 2024 en las bases de datos Scopus y Web of Science,
aplicando criterios de inclusión que abarcaron estudios en acceso abierto, revisados por pares, enfocados en el ámbito empresarial y que trataran la responsabilidad social o la innovación. De los 441 estudios identificados, 14 fueron seleccionados para el análisis. Los resultados indican que tanto la responsabilidad
social como la innovación verde contribuyen significativamente al desempeño
organizacional, promueven prácticas sostenibles y fortalecen la ventaja competitiva. En conclusión, la sinergia entre ambos elementos permite a las empresas
adaptarse a los desafíos contemporáneos, impulsando el desarrollo sostenible y
mejorando su competitividad.
Tableaux de Guerre. La representación arquitectónica de escenarios territoriales
Authors: Elvira Peña Juan , Rodríguez Ramírez Fernando
Published: December 2024

El empleo de escenarios y narrativas contrafactuales es una de las herramientas más útiles para, a partir del análisis de complejas dinámicas territoriales, desvelar posibles futuros de nuestro hábitat. Para representarlas, este texto indaga en la necesidad de emplear formatos gráficos que combinen un análisis estratégico y cartográfico junto con un retrato detallado de todos aquellos componentes, humanos, naturales y tecnológicos, que lo habitan. El tableaux de guerre contiene muchas de las cualidades necesarias para construir las cosmografías que permitan comunicar narrativas en el  seno de ecosistemas territoriales. El análisis de la transformación de este género pictórico a través de diversos ejemplos permite extraer numerosas herramientas gráficas y comunicativas que convergen con momentos clave de la modernidad arquitectónica. Iluminan aproximaciones conceptuales y modos de  representación del conflicto territorial que adquieren una nueva relevancia en nuestros días.
Discontinuidad y multiplicación: génesis de un léxico gráfico para la vivienda flexible en la modernidad
Authors: Soler Montellano Agatángelo , Sánchez Carrasco Laura
Published: December 2024

Mientras que los trabajos clásicos sobre la flexibilidad en la vivienda se han centrado en definir el sentido de esta idea y en el estudio de las herramientas de proyecto precisas para lograrla, la cuestión de su representación gráfica no ha sido tratada aún en profundidad. Este artículo se plantea como una primera aproximación a la manera en la que los arquitectos de la modernidad comenzaron a experimentar con distintos códigos para plasmar este nuevo concepto. El estudio se circunscribe al ámbito de la arquitectura doméstica en la modernidad, aunque forma parte de una investigación más amplia acerca de la flexibilidad en la vivienda. En el artículo se defiende la tesis de que, si bien el concepto de flexibilidad se ha abordado desde posiciones muy distantes a lo largo del tiempo, su representación gráfica ha mantenido los códigos implantados en la modernidad, y que estos variaban en función del medio al que se destinaban los dibujos.
Entre el paisaje, el arte y la arquitectura. RCR arquitectes y su relación con el Land Art
Authors: Hidalgo Núñez Francisco Antonio , Giménez Ribera Manuel , Sender Contell Marina , Hidalgo Núñez Álvaro
Published: December 2024

A comienzos de la década de 1960, cuando el expresionismo abstracto dejó de ser la corriente dominante en las artes visuales estadounidenses, varios artistas, algunos bajo la etiqueta del “Land Art”, iniciaron una exploración diversa, compartiendo un enfoque unificador: la utilización del paisaje como escenario del arte. Un singular lienzo que interactúa con los elementos introducidos.
El trabajo de RCR arquitectes, en especial los proyectos desarrollados en la zona de la Garrotxa, consigue dotar al entorno de un papel protagonista en sus obras, buscando la interacción de los formalismos arquitectónicos con las distintas percepciones que ofrece la naturaleza, lo que queda evidenciado en la representación gráfica de sus planos y proyectos.
El presente artículo busca analizar la significativa función que el paisaje desempeña en las obras de RCR arquitectes, mostrando las conexiones y paralelismos existentes entre su  obra y la corriente artística Land Art, mediante el análisis de algunas de sus obras más representativas.
Evaluating the effects of adaptive therapeutic climbing on the strength and well-being of patients with upper limb differences: A pilot study
Authors: Lightdale-Miric Nina , Tarrasch Allison , Hanley Diana , Hauschild Maia , Padilla Abigail , Wren Tishya
Published: December 2024

Purpose: This study aimed to determine the feasibility and potential impact of adaptive therapeutic climbing (TC) program as an intervention to improve both psychosocial health and hand function of children with congenital upper limb differences (CULDs).
Methods: Participants completed 6 weeks of 1-hour group adaptive TC sessions with pre- and post-participation functional tests of active and passive range of motion (ROM) and manual muscle testing as well as evaluations for psychosocial impact using the Questionnaire for Measuring Health-Related Quality of Life in Children and Adolescents, Perceived Life Satisfaction Scale, and Patient-Reported Outcomes Measurement Information System short forms. Feasibility outcomes of the program were also evaluated.
Results: Although seven children began the study, three children dropped out due to socioeconomic hardship related to attendance. Of the four that completed the study, two participants with symbrachydactyly (complete absence of one hand) demonstrated improvement in contralateral tip pinch and bilateral shoulder ROM. Active and passive ROM for shoulder flexion and abduction improved in all children by at least 20° bilaterally. Overall, mean psychosocial scores were similar among study participants and healthy peers. Participants consistently attempted more climbs and some even higher grade routes.
Conclusion: Adaptive TC programs are likely impactful and safe for children with CULD and may improve function and flexibility of affected and unaffected limbs. Obstacles preventing attendance affected families of lower socioeconomic status.
Offering mental health supports to college students in a rock climbing course: A recreational therapy program evaluation
Authors: Obray Elizabeth , Nelson Rhonda
Published: December 2024

This program evaluation was part of a broader research study that aimed to evaluate a new recreational therapy (RT) program focused on developing resiliency and self-efficacy in college students through a combination of rock climbing, mindfulness, and reflective journaling activities. RT programming was imbedded in an introductory college rock climbing course offered over three consecutive days, and participants experienced significant increases in resiliency and self-efficacy post-program. Given the multifaceted structure of the intervention, this program evaluation aimed to (a) clarify the role of specific program elements by assessing the RT program’s alignment with its 12 intended objectives and (b) determine the program’s appropriateness for its intended clientele by assessing perceived value to college students. Evaluation surveys revealed that 11 of the 12 objectives (91.67 percent) were met based on established thresholds for participant feedback, indicating that the program content and activities were well aligned with the intended objectives. Additionally, all of the participants (N = 12) either agreed (n = 4) or strongly agreed (n = 8) that the program had value to them.
Social media and disaster management by the National Emergency Management in Nigeria: What it is and what it should be
Authors: Kasim Oluwasinaayomi Faith , Oyerinde Ismail Adedapo
Published: December 2024

The environment for communicating about emergencies and disasters has changed as a result of the development of mobile technologies and social media applications. The public expects emergency management agencies to monitor, respond to, and report disasters via mobile applications due to this shift. This study, using the retrospective approach, analyzes the posts by the National Emergency Management Agency (NEMA) on social media in Nigeria. Activities reported via the agency’s verified social media handles (Facebook®) between 2015 and 2021 serve as the data source. Findings revealed that social media is a useful tool in disaster management, as disaster-related activities and events across the management cycle were posted by NEMA’s national and zonal offices. Most posts (45.0 percent) focused on response activities, while the recovery phase (2.0 percent) had the least posts. There was a significant variation in the reporting across the disaster management cycle (F(4,30) = 9.746). Attention should be placed on shifting NEMA from post-disaster activities to a predisaster-focused agency. Therefore, the agency should develop a social media policy and train its information officers to use the medium to engage actively with the public, especially regarding information on predisaster management activities.
Tornado sheltering: Challenges and solutions including public storm shelters
Authors: Croskery Craig D. , Sherman-Morris Kathleen
Published: December 2024

Tornadoes are a considerable threat across the United States, occurring in many regions of the country on a frequent basis throughout the year. Finding a safe place to go during a tornado can be a challenge for many individuals, and, in some situations, there is no safe place available. Increasing the number of tornado shelters and establishing them in regions where they are not currently present can greatly improve the safety of local residents and visitors, especially for those who are unable to afford retrofitting a shelter into their own home or business. Research is lacking regarding the use of such public shelters. To better understand tornado sheltering behavior, an online survey was conducted with about 1,450 people. The survey examined current tornado sheltering behavior in locations with and without public shelters available, as well as hypothetical behavior if the respondent’s location acquired a public shelter. A majority of respondents in the Deep South and Great Plains reported living in a county or community with a public shelter. While a majority of respondents have never used a public tornado shelter, the majority of those surveyed mentioned that they would utilize such shelters, at least during extreme threats. Actual use is also higher among mobile home residents. Consistent wayfinding and policies (such as pet accommodation) should also be implemented to ensure their use and promotion, and mobile applications should identify their locations.
Skills for Psychological Recovery train-the-trainer program: For care providers of children with special healthcare needs and disabilities during COVID-19 recovery
Authors: Shearer Madeline W. , Carlson Nancy J. , Yeats Janet R.
Published: December 2024

Care providers, including both professional and family caregivers, were negatively impacted by the pandemic. In partnership with the Minnesota (MN) Pediatric Care Coordination Community of Practice, the MN Department of Health Regional Behavioral Health Coordinator team provided a 7-week training of trainers in Skills for Psychological Recovery (SPR) to care providers of adults and children with special healthcare, mental health needs, and disabilities. The goal of SPR training was to protect the mental health of disaster survivors, enhance their abilities to address needs and concerns, teach skills to promote recovery, and prevent maladaptive behaviors while identifying and supporting adaptive behaviors. Weekly sessions presented skills to gather information and prioritize assistance, build problem-solving capacity, promote positive activity, manage reactions, promote helpful thinking, and rebuild healthy social connections. Data were collected during registration on the community challenges they are dealing with due to coronavirus disease 2019 (COVID-19), how COVID-19 has impacted them personally and/or professionally, and what they hoped to gain from this training. Data were also collected during the training regarding the quality of the training and the skills that they were learning through weekly feedback forms. Post-training data were collected on how they plan to use the SPR. This case study article will discuss collected data and outcomes and provide information on how to conduct the SPR training for replication. The article will also discuss limitations and future research possibilities.
Pharmacist-initiated naloxone discharge prescribing for high-risk hospitalized internal medicine patients
Authors: Wermers Michaela Elise , Sturm Ashley Weisensel , Mancini Sarah Aileen , Hogan Breann Mary
Published: December 2024

Pharmacists nationwide may play a critical role in expanding naloxone access after several states enacted legislation to allow pharmacist prescribing of opioid antagonists. This created a unique opportunity for inpatient pharmacists to participate in combating the opioid epidemic by prescribing naloxone at hospital discharge. A multifaceted intervention was developed to identify and educate hospitalized patients eligible for naloxone prescribing. After implementation, 22 of 40 eligible patients (55 percent) were prescribed naloxone by inpatient pharmacists during the 3-month study period. With this pharmacist-driven intervention, there was an 848 percent increase in the number of hospitalized chronic opioid patients with naloxone prescriptions on discharge.
Should baseline/routine ECG monitoring be performed for patients on buprenorphine-containing medications?
Authors: Boedeker Kayla , Fraley Megan , Toppins Sarah , Herndon Chris
Published: December 2024

While buprenorphine has gained widespread use in the treatment of opioid use disorder (OUD), this agent is becoming increasingly popular as a primary analgesic in those persons with pain severe enough to require chronic opioid therapy.
Authors: Sari Mutiara Novita , Adya Rahel Saffana , Trikiswoyo Muhammad Iqbal , Sugiarti Yuni
Published: December 2024

Kemudahan akses informasi menjadi kebutuhan utama mahasiswa dalam mendukung keterlibatan mereka pada kegiatan kampus. Unit Kegiatan Mahasiswa (UKM) di Universitas Islam Negeri (UIN) Jakarta memainkan peran penting dalam pengembangan potensi mahasiswa, namun keterbatasan dalam penyebaran informasi kegiatan UKM mengurangi partisipasi mahasiswa. Penelitian ini bertujuan untuk merancang prototipe Knowledge Management System (KMS) terpusat yang dapat meningkatkan aksesibilitas informasi kegiatan UKM serta mendukung pengelolaan pengetahuan. Metode Rapid Application Development (RAD) digunakan untuk pengembangan sistem karena menekankan iterasi cepat dan keterlibatan pengguna secara aktif. Pemodelan sistem dilakukan menggunakan Unified Modeling Language (UML), dengan Use Case Diagram untuk mendeskripsikan kebutuhan fungsional utama dan Class Diagram untuk menggambarkan struktur data serta hubungan antar komponen sistem. Prototipe KMS mencakup fitur pencarian informasi, dokumentasi, dan forum diskusi yang mendukung kolaborasi antaranggota UKM dan memudahkan mahasiswa umum untuk mengakses informasi terkait kegiatan UKM. Hasil penelitian menunjukkan bahwa KMS mampu meningkatkan aksesibilitas informasi, mendukung dokumentasi kegiatan UKM secara terpusat, dan memfasilitasi sinergi antar organisasi kampus. Dengan sistem ini, mahasiswa dapat dengan mudah menemukan informasi yang relevan, sehingga meningkatkan keterlibatan mereka dalam kegiatan UKM. Prototipe ini memberikan solusi awal yang efektif dalam mengatasi permasalahan akses informasi di lingkungan UKM dan dapat menjadi landasan untuk pengembangan sistem lebih lanjut melalui pengujian prototipe.
Analisis Pelanggan Potensial Dengan Algoritma K-Means Untuk Meningkatkan Jumlah Paket Pada PT Cipta Teknindo Rekatama
Authors: Kari Albianus Arfan , Sofica Verra
Published: December 2024

Dalam dunia bisnis hubungan antara pelaku bisnis dengan klien (pelangggan) sangatlah penting. Dimana perusahaan harus bisa mempererat hububungan dengan pelanggannya termasuk untuk pengenalan pelanggan potensial. Perusahaan menyadari akan pentingnya hubungan antara pelanggan yang loyal dengan keberhasilan bisnis perusahaan, serta Gaya hidup masyarakat saat ini ikut berubah karena pengaruh dari perkembangan teknologi tersebut, salah satu yang paling mencolok dari perkembangan teknologi tersebut adalah gadget dan kecenderungan beraktivitas di dunia maya seperti berbelanja secara online atau lebih sering disebut dengan belanja online. PT Cipta Teknindo Rekatama merupakan perusahaan yang bergerak di jasa pengiriman paket. PT Cipta Teknindo Rekatama berjalannya sangat cepat dan pemasaran dapat dilakukan secara global. Jumlah paket yang ada juga membantu PT Cipta Teknindo Rekatama untuk mengetahui pelanggan potensial yang tepat. Akan tetapi, masih ada permasalahan yang ditemukan dalam pengiriman paket pada perusahaan ini yaitu tidak adanya peningkatan untuk paket masuk dalam beberapa tahun terakhir. Oleh sebab itu, perlu penentuan pelanggan potensial dalam meningkatkan jumlah paket pada PT Cipta Teknindo Rekatama melalui pola-pola dari kumpulan data dengan metode Clustering (Pengelompokan) dengan menggunakan Algoritma K-Means. Algoritma K-Means meenjadi salah satu metode dalam fungsi clustering atau pengelompokan. Clustering mengacu pada pengelompokan data, observasi atau kasus berdasarkan kemiripan objek yang diteliti. Hasil dari penelitian ini diharapkan dapat memudahkan PT Cipta Teknindo Rekatama dalam menganalisis pelanggan potensial sehingga mendapatkan informasi jumlah paket yang di terimannya.
Optimasi Manajemen Stok Barang Berbasis Prediksi pada Perusahaan Konfeksi dengan Algoritma Single Moving Average
Authors: Somantri Asep , Muttaqin Miftahul Fadli
Published: December 2024

Manajemen stok yang optimal merupakan salah satu faktor kunci dalam meningkatkan efisiensi operasional perusahaan konfeksi. Ketidakseimbangan antara permintaan bahan baku dan ketersediaan stok dapat menyebabkan risiko kekurangan atau kelebihan stok, yang berdampak pada biaya penyimpanan dan kelancaran produksi. Penelitian ini bertujuan untuk mengembangkan algoritma prediksi berbasis Single Moving Average (SMA) guna mengoptimalkan pengelolaan stok bahan baku pada perusahaan konfeksi. Data historis permintaan bahan baku dikumpulkan, lalu algoritma SMA diterapkan untuk meramalkan kebutuhan stok pada periode mendatang. Penelitian ini melibatkan studi kasus pada sebuah perusahaan konfeksi dengan data permintaan bahan baku selama beberapa periode. Hasil penelitian menunjukkan bahwa algoritma SMA mampu memberikan prediksi yang akurat untuk kebutuhan stok, serta membantu perusahaan dalam efisiensi penyimpanan dan meminimalkan risiko kekurangan stok. Selain itu, penelitian ini memberikan rekomendasi untuk peningkatan kinerja prediksi pada masa yang akan datang.
Ethnic, Educational, and Occupational Dimensions of Domestic Violence in Southern Nigeria.
Authors: Kehinde Omotoso T. , Sunday Adewara O. , Oluwayemisi Adeleke
Published: December 2024

Purpose: This study examined the effect of a married woman’s ethnicity, education, and occupation on domestic violence in Southern Nigeria. The specific goals are to determine the impact of ethnicity, education, and occupation on domestic violence in Southern Nigeria, and assess the determinants of domestic violence in Southern Nigeria.

Design/Methodology/Approach: The data from the 2018 Demographic Health Survey (DHS) was analysed using the logit and ordered logit regression techniques. The study considered married women aged between 15- 50 years in the Southern part of Nigeria.

Findings: Our findings show that the Ethnicity of a married woman has a positive effect on domestic violence in Southern Nigeria, In the region, being Yoruba, Hausa, and Ijaw reduces the odds of a woman suffering domestic violence. Education has a positive impact on domestic violence, indicating that, the more educated the partner is, the lesser the odds of a woman suffering domestic violence. Gainfully employed women are more prone to suffer domestic violence in Southern Nigeria, that is, having a job increases the odds of a woman suffering domestic violence.

Conclusion: At the end of the study, it was discovered that ethnicity and occupation have a positive effect on domestic violence, while education on the other hand is negatively related to domestic violence in Southern Nigeria.
Presentación del dossier “Santa Fe. El largo proceso de su consolidación urbana y proyección territorial”
Authors: Damianovich Alejandro A.
Published: December 2024

Presentación del dossier “Santa Fe. El largo proceso de su consolidación urbana y proyección territorial”
The Legal Position Of Marriage Agreements Regarding Land Rights In Mixed Marriages In Indonesia
Authors: Yulia Ardana Shindi , Taruno Muryanto Yudho , Dyah Kusumawati Erna
Published: December 2024

The purpose of this article is to analyze the legal position of prenuptial agreements in mixed marriages regarding land rights. The type of research used is normative legal research that investigates the systematics of law. This systematic legal research is conducted on laws and regulations or laws that are in accordance with the topic raised. The results of the study indicate that making a prenuptial agreement for the separation of property in mixed marriages is an effective way to resolve cases related to land rights in mixed marriages. Settlement of land ownership disputes in mixed marriages without a prenuptial agreement in Indonesia is by filing a request for separation of property by one of the husband and wife to the court according to their relative competence. This shows that without a prenuptial agreement, the legal process to protect land rights becomes more complex and requires court intervention. Therefore, a prenuptial agreement is considered important because it provides a more efficient path. According to the author, this settlement is the only best and legal way in the eyes of the law.
Effect Of Personalized Instruction Strategy On Pupils’ Academic Achievement In Numeracy In Ilorin West Local Government Area Of Kwara State
Authors: Arisekola Salman Azeez , Ajibola Elisha Ojo
Published: December 2024

This study focused on effect of personalized instructional strategy on pupils academic achievement in Ilorin West Local Government Area of Kwara State. The study adopted pre-test post-test control group quasi-experimental research design. A factorial design of 2X2 was adopted for the study. The population comprises of all public and private primary schools pupils. The sample size were four primary three classes. First, all the schools were divided into two strata (Private and Public), and Purposive sampling technique was used to select (2) public and (2) private schools using intact class. Three research instruments were used titled: Pupils’ Numeracy Achievement Test (PNAT) with two treatment packages, Instructional Guide for Personalized Instruction (IGPI) and Instructional Guide for Conventional Method (IGCM). Instruments were subjected to face and content validity by some selected numeracy. Test re-test method of reliability was used. Thereafter, Pearson Product Moment Correlation (PPMC) was used to determine the reliability index of  (r=.71). Three research hypotheses were formulated and tested at 0.05 level of significance. The demographic data of the participants, were analyzed using frequency counts, mean, and percentage while the research hypotheses were tested, using analysis of co-variance (ANCOVA) at 0.05 level of significance. The finding revealed among others that there was a significant main effect of treatment on pupils’ academic achievement in Numeracy in Ilorin West Local Government, Kwara State (F (1; 129) = 10.175, P< 0.05). Those exposed to Personalized Instruction (15.726) performed significantly higher than those exposed to conventional method (14.667). Based on the findings of this study, it can be explicitly stated that personalized instructional strategy can enhance better performance in Numeracy than the traditional method of teaching and learning. Recommendation were made among others, Numeracy teachers should be enlightened on the effectiveness of personalized instructional strategy on pupils’ academic performance in Numeracy.
The Influence of Social Media Marketing on Purchase Decision by Brand Awareness and Trust (For Prospective Students Telkom Unversity)
Authors: Ruli Kuniawati Novia , Ariyanti Maya
Published: December 2024

This study aims to look at the influence of social media, brand awareness, trust,and purchase decision on the purchase of PIN at Telkom University prospective new students. This influence has previously been seen from previous research and is associated with relevant theories. This research uses descriptive and typhoid approach with quantitative research type. Sampling technique used is purposive sampling, the number of samples to be analyzed is 400 respondents of new students of Telkom University class of 2020. Data analysis techniques used are Structural Equation Modeling (SEM) which is processed with LISREL 8.8 software. The results revealed that social media marketing does not have a positive and significant influence on purchase decisions, but brand awareness and trust have a positive and significant influence on purchase decisions. The study also found that the indirect effect of social media marketing on purchase decisions through brand awareness and trust is more positive and significant than direct effects and brand awareness has a positive but insignificant effect on trusts. Conclusions and suggestions for further research have been included in the study.
Legal Defects Of Sale And Purchase Deeds: A Review Of The Responsibilities Of Officials Making Land Deeds In Indonesia
Authors: Magistasari Elvina , Sentot Sudarwanto A.L. , Harahap Burhanudin
Published: December 2024

This research discusses legally defective sale and purchase deeds and the responsibilities of Land Deed Drafting Officials (PPAT) in Indonesia. Land is a vital element for fulfilling human needs, and land certificates as proof of ownership are very important in the agrarian legal system. The land buying and selling process must be carried out in accordance with legal provisions so that the resulting sale and purchase deed (AJB) has valid legal force. PPAT, as the official who has the authority to make authentic deeds, must ensure the validity of the documents and the completeness of the legal process when making AJB. Making AJB that meets formal and material requirements is very important; otherwise, legal defects may occur that result in PPAT's liability. This article examines the sanctions that can be imposed on PPAT if there are errors, both in administrative, civil and criminal contexts, in accordance with applicable laws and regulations. This research uses the nature of normative juridical research to analyze PPAT accountability and expand understanding of practices that are in accordance with law and professional ethics. The results show that PPAT has a big responsibility in maintaining the validity of deeds, and violations of legal procedures can result in serious sanctions, both administrative and criminal.
Determinants Of Financial Literacy, Digital Literacy, Internet Penetration And Consumer Confidence Level Mediated By Fintech Growth On Retail Industry Growth In Indonesia
Authors: Sapta Rini Anggarwati
Published: December 2024

This study evaluates how financial literacy, digital literacy, internet penetration, and consumer confidence influence retail industry growth in Indonesia, emphasizing the mediating role of fintech. In the era of industry 4.0, technology, especially fintech, has transformed conventional financial business models into digital ones, accelerating transactions and financial inclusion. The Covid-19 pandemic has further driven digitalization, although it has posed major challenges for the retail industry. This study aims to determine the actual impact of the development of fintech applications including the influence of financial literacy, digital literacy, internet penetration and consumer confidence levels on the development or growth of retail in Indonesia. This study uses a quantitative method with a focus on analyzing the relationship between financial literacy, digital literacy, internet penetration, and consumer confidence levels in the growth of the retail industry, both directly and through the mediation of fintech growth. The data used are secondary data that include information on the financial literacy index, digital literacy index, internet penetration level, consumer confidence index, fintech adoption level, and retail performance indicators. To overcome incomplete data, imputation and proxy variable methods are used. The analysis was conducted using multiple linear regression to identify direct relationships between variables, and structural equation modeling (SEM) to comprehensively evaluate the influence of fintech mediation. This study shows that financial literacy, digital literacy, and consumer confidence levels have a significant influence on retail growth, both with and without fintech growth mediation. Digital literacy and consumer confidence levels have a positive impact, reflecting that understanding of digital technology and consumer confidence contribute to retail development. Conversely, financial literacy shows a negative influence. Internet penetration does not show a significant influence on retail growth, either directly or through fintech mediation.
The Role of Museums in the Field of Sustainable Cultural Heritage: Opinions of Social Sciences High School Students
Authors: Koca Ramazan
Published: December 2024

Cultural heritages are tangible and intangible values that should be transferred to the future in the living environment. Museums have an important function in the protection and transfer of these values to future generations. It is thought that the level of consciousness and awareness of young people about the function of museums in the protection and maintenance of cultural heritage is important. In this sense, the aim of the research is based on examining the views of social sciences high school students on the role of museums in sustaining cultural heritage. The research was conducted using the interview technique based on the basic qualitative research model. The research group of the consists of 20 senior students studying in two different social sciences high schools. Criterion sampling, one of the purposeful sampling methods, was used in the research, and the criterion determined was that the students had visited the museum. In this context, in-depth interviews were conducted with the participants through semi-structured interview forms. The interviews continued until a certain data saturation was reached and the data were seen to repeat each other. In order to increase the validity and reliability of the study, it was ensured that the interviews were conducted objectively and that the participants were not directed. The data obtained from the interviews were first transcribed and transferred to the Nvivo 10 program and analyzed with descriptive and content analysis. As a result of the research, it was seen that the themes of “protecting”, “living”, “teaching” and “protecting our cultural values” came to the fore in sustaining cultural heritage. At the same time, it was revealed that in order to maintain cultural heritage, values can be sustained by keeping them alive or practising them. It was concluded that museums serve as a bridge in the transfer of material, spiritual, historical and cultural heritage and are effective in sustaining cultural heritage.
Archaeological Ceramics, from Scientific Research to Interpretation and Mediation; Towards the Foundation of Scientific and Cultural Project
Authors: Dammak Olfa
Published: December 2024

The scientific research carried out on archaeological ceramics provides a deeper understanding of ancient civilisations. The results can be used to trace human activities, skills and the evolution of landscapes… However, most people are disconnected from the scientific journals or newspapers where this information is presented. At this level comes the importance of interpretation and mediation both as indispensable elements of heritage conservation efforts and essential tools for public understanding of heritage. The purpose of this research is to study the project to create a scientific and cultural interpretation centre. This new concept of mediation, very rare in the Maghreb countries, appeared in America at the beginning of the XX century. It is introduced in Tunisia at the beginning of XXI with the interpretation centre of the Qasba (Tunis) which was created in 2019. The objective is to communicate to the public scientific research on archaeological ceramics and its results. The essential objective of the center is to make known the archaeological ceramics of the Tunisian Sahel as part of our heritage, by identifying their typological and petrographic specificities, which requires the complementary work of the ceramologist, the archaeologist and especially the museographer. In order to present this idea, methods should be used that stimulate the imagination of the public to convey the message without having exhibited heritage objects and cultural goods as in museums.