bluuebunny/crossref_metadata_2025 huggingface dataset:
The nomenclature and type status of Telicota paceka mesoptis Lower, 1911 (Lepidoptera: Hesperiidae)
Authors: Braby Michael F. , Beaver Ethan P.
Published: April 2022

O. B. Lower described, in 1911, the hesperiine skipper Telicota augias mesoptis Lower, 1911, but he neither stated the number of specimens before him nor designated a holotype. Our investigations indicate that Lower had at least 11 syntypes (7 males, 4 females), which are now registered in the Australian Museum, Sydney and South Australian Museum, Adelaide (SAMA). At least two authors (G. A. Waterhouse in 1933, and M. J. Parsons in 1998) attempted to resolve the taxonomy of mesoptis but neither of them made a valid lectotype designation in that the syntype they specified cannot be located and unambiguously identified to act as the unique type of the taxon. Thus, we designate a male specimen in SAMA (registration number: SAMA Database No. 31-001600) as the lectotype to become the unique bearer of the name mesoptis. This action does not affect the name or rank of the taxon, rather it constitutes a formal subsequent fixation since Lower’s name was introduced 110 years ago. With regard to nomenclature, the taxonomic status of mesoptis has changed several times, both in terms of rank and with the species or genus in which it has been combined. Currently, the correct nomenclature is Telicota paceka mesoptis Lower, 1911 and we recommend that this name be used to designate the Australian population rather than Telicota mesoptis mesoptis Lower, 1911 in which it has been known for the past 87 years (since 1934).
Relocation and formation of new local population of Viola pumila Chaix – an endangered species in Europe and identification of measures for improvement of its habitat
Authors: Kaschieva Maria Zh. , Nedyalkov Nikolay P.
Published: April 2022

The meadow violet (Viola pumilaChaix) is an endangered species which is regionally extinct in many European countries. This is a stenobiontic species with a very limited distribution in Bulgaria. Only a few populations have been detected, and they consist of several tens to several hundreds of specimens. The meadow violet has limited reproductive abilities and weak competitiveness. The species is exposed to various anthropogenic threats, as the most significant of them are related to ploughing, conversion of the mesophilic meadows into arable lands, changes in the water regime of the habitats, the expansion of highly competitive species from the group of tufted cereal grasses and infrastructure construction. To date, information concerning the relocation of rare and endangered plant species in Bulgaria is rather scarce. In the present study we provide a protocol on our activities during a successful establishment of a new locality as part of our effort to successfully relocate one particular population of the meadow violet. The observations made after the relocation of the species over a two-year period (2020 and 2021) provided data on the successful relocation, and the creation of a new locality for the species. We discuss the conservation measures needed for this rare and endangered species, and efforts to increase its population, as well as the measures needed for effective management of the habitats ofV. pumila(mainly 6510 “Lowland hay meadows”).
An analog electronic circuit model for cAMP-dependent pathway—towards creation of Silicon life
Authors: Waqas Maria , Ainuddin Urooj , Iftikhar Umar
Published: April 2022

Among the most sought after breakthroughs nowadays to combat computational saturation in the electronic hardware realm, neuromorphic and cytomorphic mimetics of biological structures seem potentially promising. Biological circuits are distinguishable due to their minuscule dimensions and immensely low power consumption; yet they achieve extremely complex and magnificent tasks of life, such as, thinking, memorizing, decision making and self-regulating in response to the surroundings. Low power analog circuit solutions are edged over digital ones as they are inherently noisy and fuzzy like bio-systems. In this paper, an analog circuit equivalent for a well-known biological pathway, cyclic adenosine monophosphate (cAMP), has been proposed, exploiting the fabrication characteristics of an analog transistor. The work demonstrates an application of previously published research of the authors, where it was shown that a single transistor operating in analog mode can mimic some fundamental biological circuit processes like receptor-ligand binding, Michaelis Menten and Hill process reactions. Since biological pathways are chain connections of such reactions, same modular approach can be used to build electronic pathways using those basic transistor circuits. Although the idea of creating silicon life seems far-fetched at this stage, this work supplements the idea of cytomorphic chips which is already gaining interest of bio-engineering community.
Carbon monoxide and nitrogen dioxide patterns associated with changes in energy use during the COVID-19 pandemic in Kenya
Authors: Ang'u Cohen , Muthama Nzioka John , Mutuku Mwanthi Alexander , M'IKiugu Mutembei Henry
Published: April 2022

Environmental degradation, including air quality deterioration, has been mainly attributed to anthropogenic activities. Air pollution has become a pressing issue in industrialised and highly populated areas due to the combustion of fossil fuels and industrial operations. Recently, the COVID-19 pandemic led to a nationwide lockdown to control the spread of the coronavirus. This imposed restrictions on many economic activities, thus providing the environment with an opportunity to heal. The COVID-19 response measures adopted by most countries, including lockdown, restricted movement, and other containment measures, led to a significant decrease in energy use in the transport sector. Due to low electricity access levels in developing countries, traditional energy sources make up the bulk of energy used for most domestic energy services. Biomass combustion emits carbon monoxide (CO), while the transport sector is a major contributor of nitrogen dioxide (NO2). This study was purposed to investigate the short-term effects of COVID-19 on CO and NO2 concentration levels in Nairobi, Vihiga and Tana River counties. The study utilised data on CO surface concentration, NO2 column concentration and reported COVID-19 cases. Time series, correlation analysis and spatial and temporal map analysis were carried out to investigate the changes and relationships among the study parameters. The three counties were selected based on the urbanisation and population. Nairobi county represented an urban setting, while the Vihiga and Tana River counties represented rural areas with high and low population densities, respectively. The CO surface concentrations in Nairobi and Vihiga county significantly correlated with the COVID-19 cases, with both counties portraying negative correlations, i.e., −0.59 (P-value: 0.008) and −0.45 (P-value: 0.05), respectively. NO2 column concentration also exhibited a significant negative relationship with reported COVID-19 cases in the Vihiga (−0.018, P-value = 0.05) and Tana River (0.17, P-value = 0.00) counties. These findings highlight the need for demographic and economic considerations in CO and NO2 assessments, and allude to a decreased health risk due to CO and NO2 emissions during the COVID-19 pandemic.
Knowledge, attitudes on falls and awareness of hospitalized patient's fall risk factors among the nurses working in Tertiary Care Hospitals
Authors: James Kavin Mozhi , Ravikumar Divya , Myneni Sindhura , Sivagananam Poonguzhali , Chellapandian Poongodi , Manickaraj Rejili Grace Joy , Sargunan Yuvasree , Kamineni Sai Ravi Teja , Veeraraghavan Vishnu Priya , Kullappan Malathi , Mohan Surapaneni Krishna
Published: April 2022

Background

Fall is the most common patient safety incident in health care organizations. This study was initiated to obtain information regarding knowledge & attitude on falls and awareness of fall risk factors among nurses to device evidence-based and multidisciplinary educational and training programs to improve patient safety and thereby reduce morbidity and mortality associated with falls.

Methods

A descriptive cross-sectional survey study was conducted among 339 registered nurses working in Tertiary care hospitals across Chennai, Tamil Nadu, India. A modified version of the previously validated standard questionnaire was administered by the investigators through an online survey method to explore the level of knowledge & attitude on falls and awareness of inpatient fall risk factors among Nurses.

Results

In this study, 15.6% of participants had adequate knowledge of falls, 57.2% had a favorable attitude towards falls and 38.3% had adequate awareness of fall risk factors. Years of experience in nursing has a statistically significant association with the level of knowledge on fall. The participant's attitude towards falls had a statistically significant relationship with age, education, experience in nursing, and previous patient fall experience. The correlation between fall knowledge, the attitude toward falls, and awareness of fall risk factors were highly significant. The majority of the participants expressed their favorable attitude toward the need for fall preventive education.

Conclusion

In our study, it is evident that there is a void that has to be filled to improve the knowledge, attitude, and awareness of falls and their risk factors. There is a need for extensive education and holistic, multifactorial, and interdisciplinary training program to be undertaken through various health care organizations.
Singular Kähler-Einstein metrics on $ \mathbb Q $-Fano compactifications of Lie groups
Authors: Li Yan , Tian Gang , Zhu Xiaohua
Published: April 2022

In this paper, we prove an existence result for Kähler-Einstein metrics on $ \mathbb Q $-Fano compactifications of Lie groups by the variational method, provided their moment polytopes satisfy a fine condition. As an application, we prove that there is no $ \mathbb Q $-Fano $ {\rm SO}_4(\mathbb C) $-compactification which admits a Kähler-Einstein metric with the same volume as that of a smooth K-unstable Fano $ {\rm SO}_4(\mathbb C) $-compactification.
Imperatores forma ac decore corporis […] comparantibus (Tacite, Histoires, 1.7)
Authors: Autin Louis
Published: April 2022

Les discours populaires sur le corps des Princes au ier siècle ap. J.-C. sont souvent dénigrés par différents moyens dans les sources littéraires qui les transmettent : à en croire les historiens et biographes impériaux, ils ne traduisent que l’attachement du peuple à l’inanité de l’apparence physique et mettent en évidence la dépolitisation des foules urbaines dans le régime impérial. Or, le mépris du corps comme objet politique a toutes les chances d’être le signe d’un vernis aristocratique et ne semble pas se vérifier, pour autant qu’on puisse la saisir, dans la « culture plébéienne ». Partant de ce constat, nous essayons, à l’aide de la philosophie du pouvoir de Michel Foucault, de rendre à ces discours collectifs et anonymes sur la corporéité des dirigeants toute leur valeur politique, en rappelant d’abord l’importance sur le quotidien de la plèbe des aspects pragmatiques liés à la bonne santé du Prince, puis en étudiant comment l’image plébéienne du corps de l’empereur servit de point de bascule à des discours contestataires : en désignant le corps de tel ou tel aristocrate comme « princier », les foules pouvaient réussir à délégitimer indirectement le pouvoir en place.
Menstrual Blood: Uses, Values, and Controls in Ancient Rome
Authors: Chavarria Sophie
Published: April 2022

The purpose of this article is to examine the positive and negative properties of menstrual blood in Ancient Rome and its related uses. Building on such premises, I go on to explore the cultural practices involving this ambivalent substance. I argue that menstrual blood and its powers were manipulated to reinforce male order and state control over women’s bodies, becoming an instrument justifying the enactment of new rules to control Roman women. On the other hand, far from pushing away women from public and sacred spaces, the powers of menstruation contributed to strengthen their integration into the life of the city.
Fidelity and Play Model
Authors: Stofella Arthur , Fadel Luciane Maria
Published: April 2022

Serious games need to reflect reality to achieve their purpose, whether learning, training, or provoking a behavioral change. At the same time, serious games employ features that make gaming a self-motivating, engaging, and fantastic activity. This chapter presents a conceptual model to support the design of serious games that deals with the balance between fidelity and play. Design science research guided the model development. Fidelity was conceived as a field force that attracts fun, motivation, and engagement. The model arranged the game elements into three major groups: the Game-World, the Interaction-World, and the Player's-World. Fidelity can assume different levels in each of these worlds. The Fidelity and Play model (FP) allows a holistic view of the relationship and balance between fidelity and play in a serious game.
Money Management
Authors: Gonzaga Ana Maria , Lamas Maria Céu
Published: April 2022

With the increase in average life expectancy and the demographic ageing of the worldwide population, several challenges have emerged at the social, economic, and health are levels. To improve this process, the WHO advocates active ageing, where cognitive stimulation is one of the important aspects to consider for the adoption of a healthy lifestyle and the care of one's mental health. In this framework, serious games can bring more benefits to older people and caregivers. In order to assess the contribution of serious games, a bibliographic research was carried out in the Web of Science database, using the terms “serious game” and “elderly.” It is found that the use of serious games has benefits in several domains. Within the scope of cognitive stimulation, there are several games, although they do not value the difficulties that individuals have in their IADLs. In this context, it is important to stimulate skills related to money management. This intervention will help to maintain daily living skills and optimize responses to functional losses, resulting in active aging.
Experimental Investigation of Air Bubble Curtain Effects on Water Wave Field
Authors: Neves Diogo R.C.B. , Brito Moisés , Pires-Silva António Alberto , Fortes Conceição Juana , Matos Jorge
Published: April 2022

This paper studies the effects of an air bubble curtain on surface water waves. Water particle velocities and free surface elevations were measured simultaneously at two cross-shore locations downstream of the air bubble curtain. Measurements were carried out for regular waves using different air bubble curtain configurations. Free surface elevations were measured using resistive gauges and the instantaneous velocities were acquired using an Acoustic Doppler Velocimeter (ADV). The characteristics of the free surface elevation time series, velocity field and turbulence are analyzed and discussed. The free surface elevation was found to be attenuated by the air bubble curtains. The phase averaged velocity profiles also depict the effect of the air bubbles in the flow field by generating milder longitudinal velocities (u) and by increasing the transverse component of the velocity (w). The increase in the turbulence intensity and the different energy spectrum produced by the air bubble curtain is also observed. The experimental results indicate that the thickness of the air bubble curtain and the total air flow rate affects the wave field.
Thermophoretic and Suction/blowing Effects on MHD Mixed Convection Flow over an Inclined Plate Combined with Heat Generation, Chemical Reaction and Radiation
Authors: Khemissat Boualem , Bouaziz Amina Manel , Bouaziz M.N.
Published: April 2022

This paper examined the thermophoresis effect and suction/injection process on steady MHD in a semi-infinite inclined porous plate. Chemical reaction, heat generation and thermal radiation are taking into account. The governing partial diﬀerential equations are transformed via similarity technique into a system of nonlinear ordinary diﬀerential similarity equations, which are solved numerically by applying the Lobbato IIIa-finite-difference method. Favorable comparisons with previously published work are performed. Numerical pertinent results for the velocity, temperature and concentration profiles as well as for the skin-friction coefficient, wall heat transfer and mass transfer rates are obtained and reported graphically for various parametric conditions to show interesting aspects of the solution. The main results are the dominant influence of suction/injection process to control the principal boundary layers and the role played by the combined chemical reaction, heat generation and thermal radiation on the changes in the quantities of interest.
Temperature Distribution Comparison in Smooth and Stepped Functions
Authors: Lebelo Ramoshweu Solomon , Barros Willfried , Akindeinde Saheed Ojo
Published: April 2022

In this article the distribution of temperature in both smooth and stepped functions is compared. The study uses a model of one dimensional N-cross-sections domain of a vase shaped medium, where approximation of the solution in the first case uses smooth functions, and in the second one, stepped functions. The temperature distribution is described by heat equation. Analysis of temperature distribution in both cases is based on finding eigenvalues and their corresponding eigen-functions which satisfy boundary conditions at given endpoints. Mathcad software was applied to determine the eigenvalues and their corresponding eigen-functions, together with the temperature distribution in the media of concern. The temperature distribution in both cases was found to be basically the same. The problem solution for each case is presented and an example of a one-dimensional vase shaped domain of length 4 units for each case is also given.
Calculation and Experimental Method of Evaluation of Residual Working Resource of Reinforced Rods of Concrete Structures of Hydrotechnicalreinforced Structures
Authors: Makarenko Yu. V. , Maksimov Sergey Yu. , Khoruzhiy Viktor
Published: April 2022

The work carried out complex and systematic studies based on of which the causes of accidental destruction of reinforcement of reinforced concrete structures of hydraulic structures is established, which is that corrosion damage to metal reinforcement is accompanied by its active flooding and embrittlement, resulting in reduced material properties against corrosion and mechanical destruction of reinforced concrete structures, especially after 20-40 years of operation. Based on existing approaches to the assessment of ageing equipment, developed in various branches of mechanical engineering, including the construction industry, identified trends and shortcomings in determining the efficiency of metal structures and their residual life, in connection with which the calculation and experimental methods of using the criteria of crack resistance, sensitive to changes in the structure of the metal during long-term operation. It is established that the decrease in crack resistance characteristics in the surface layers of reinforcement of reinforced concrete structures in contact with the aggressive environment is caused by the degrading effect of hydrogen on the crystal structure of the metal. The calculated-experimental method is offered, allowing to carry out engineering forecast estimation of residual (working) resource of the reinforced concrete designs operated in corrosive-aggressive environments of hydraulic engineering constructions, which adequately reflects physical and mechanical processes in metal which occur during its long operation.
Secreted key regulators (Fgf1, Bmp4, Gdf3) are expressed by PAC1-immunopositive retinal ganglion cells in the postnatal rat retina
Authors: Dénes Viktória , Kovacs Kármen , Lukáts Ákos , Mester Adrienn , Berta Gergely , Szabó Arnold , Gabriel Robert
Published: April 2022

Identified as a member of the secretin/glucagon/VIP superfamily, pituitary adenylate cyclase-activating polypeptide (PACAP1-38) has been recognized as a hormone, neurohormone, transmitter, trophic factor, and known to be involved in diverse and multiple developmental processes. PACAP1-38 was reported to regulate the production of important morphogens (Fgf1, Bmp4, Gdf3) through PAC1-receptor in the newborn rat retina. To follow up, we aimed to reveal the identity of retinal cells responsible for the production and secretion of Fgf1, Bmp4, and Gdf3 in response to PACAP1-38 treatment. Newborn (P1) rats were treated with 100 pmol PACAP1-38 intravitreally. After 24 h, retinas were dissected and processed for immunohistochemistry performed either on flat-mounted retinas or cryosections. Brn3a and PAC1-R double labeling revealed that 90% of retinal ganglion cells (RGCs) expressed PAC1-receptor. We showed that RGCs were Fgf1, Bmp4, and Gdf3-immunopositive and PAC1-R was co-expressed with each protein. To elucidate if RGCs release these secreted regulators, the key components for vesicle release were examined. No labeling was detected for synaptophysin, Exo70, or NESP55 in RGCs but an intense Rab3a-immunoreactivity was detected in their cell bodies. We found that the vast majority of RGCs are responsive to PACAP, which in turn could have a significant impact on their development or/and physiology. Although Fgf1, Bmp4, and Gdf3 were abundantly expressed in PAC1-positive RGCs, the cells lack synaptophysin and Exo70 in the newborn retina, thus unable to release these proteins. These proteins could regulate postnatal RGC development acting through intracrine pathways.
Influential Factors and Preliminary Reference Data for a Clinically Feasible, Functional Reaction Time Assessment: The Standardized Assessment of Reaction Time
Authors: Lempke Landon B. , Oldham Jessie R. , Passalugo Scott , Willwerth Sarah B. , Berkstresser Brant , Wang Francis , Howell David R. , Meehan William P.
Published: April 2022

Context

Clinical reaction-time (RT) measures are frequently used when examining patients with concussion but do not correlate with functional movement RT. We developed the Standardized Assessment of RT (StART) to emulate the rapid cognitive demands and whole-body movement needed in sport.

Objective

To assess StART differences across 6 cognitive-motor combinations, examine potential demographic and health history confounders, and provide preliminary reference data for healthy collegiate student-athletes.

Design

Prospective, cross-sectional study.

Setting

Clinical medicine facilities.

Patients or Other Participants

A total of 89 student-athletes (56 [62.9%] men, 33 [37.1%] women; age = 19.5 ± 0.9 years, height = 178.2 ± 21.7 cm, mass = 80.4 ± 24 kg; no concussion history = 64 [71.9%]).

Main Outcome Measure(s)

Student-athletes completed health history questionnaires and StART during preseason testing. The StART consisted of 3 movements (standing, single-legged balance, and cutting) under 2 cognitive states (single task and dual task [subtracting by 6's or 7's]) for 3 trials under each condition. The StART trials were calculated as milliseconds between penlight illumination and initial movement. We used a 3 × 2 repeated-measures analysis of variance with post hoc t tests and 95% CIs to assess StART cognitive and movement differences, conducted univariable linear regressions to examine StART performance associations, and reported StART performance as percentiles.

Results

All StART conditions differed (P ≤ .03), except single-task standing versus single-task single-legged balance (P = .36). Every 1-year age increase was associated with an 18-millisecond (95% CI = 8, 27 milliseconds) slower single-task cutting RT (P < .001). Female athletes had slower single-task (15 milliseconds; 95% CI = 2, 28 milliseconds; P = .02) and dual-task (28 milliseconds; 95% CI = 2, 55 milliseconds; P = .03) standing RT than male athletes. No other demographic or health history factors were associated with any StART condition (P ≥ .056).

Conclusions

The StART outcomes were unique across each cognitive-motor combination, suggesting minimal subtest redundancy. Only age and sex were associated with select outcomes. The StART composite scores may minimize confounding factors, but future researchers should consider age and sex when providing normative data.
Retinoic Acid Receptor Responder Protein 2 and Intelectin-1 in Visceral Adipose Tissue from Pregnant Women with Gestational Diabetes Mellitus
Authors: García Betsy Corina Sosa , Juárez Araceli Consuelo Hinojosa , García María del Carmen García , Pérez-Amado Carlos Jhovani , Jiménez-Morales Silvia , Zerón Hugo Mendieta
Published: April 2022

ABSTRACT

Introduction:

The adipose tissue secretes chemerin and omentin related to metabolic diseases. It has been reported that both proteins encoded by retinoic acid receptor responder protein 2 (RARRES2) and intelectin-1 (ITLN1) genes, respectively, are abnormally expressed in gestational diabetes mellitus (GDM).

Aim:

To evaluate the expression of these genes in visceral adipose tissue in pregnant women with GDM.

Methods:

Descriptive cross-sectional study, with two groups, (A) GDM and (B) control group (pregnant women without GDM). Body mass index (BMI), blood pressure, lipids, and glucose were measured. RARRES2 and ITLN1 mRNA expression were evaluated using quantitative real-time Reverse transcription-polymerase chain reaction using TaqMan probes. Statistical analysis was performed using Kolmogórov–Smirnov, Pearson-Spearman correlation, Kruskal–Wallis tests, and R language with Shapiro–Wilk, SPSS V21.0.

Results:

Sixty-six women were included. Women with normal weight were more frequent in the control group (33.3%) than GDM (15.2%); overweight was similar in both groups (45.5%), and obesity was less common in the control group (21.2%) than GDM (39.3%). No differential expression of RARRES2 and ITLN1 genes among cases and controls were found, but RARRES2 expression differed (P = 0.016) between normal-weight and overweight women in the control group, and ITLN1 expression significantly differed (P = 0.002) between overweight and obese women in the GDM group.

Conclusions:

ITLN1 could have a role in the GDM severity based on the BMI of the patients.
Relation of Expressed Emotions and Burden of Care in Primary Caregivers to Severity of Illness in Schizophrenia Patients: A Cross-Sectional, Hospital based Study
Authors: Bhowmik Mandakini , Gaekwad Sudhir J. , Chaudhury Suprakash , Prakash Jyoti , Saldanha Daniel
Published: April 2022

ABSTRACT

Background:

Negative expressed emotions are a significant characteristic of the family milieu that has been found to predict symptom relapse in schizophrenia and may be related to severity of illness and burden of care.

Aim:

The aim of this article is to study the expressed emotions and burden of care in primary caregiver of patients suffering from schizophrenia, with relation to severity of illness.

Methods:

This cross-sectional, hospital-based study included 60 schizophrenia patients and their primary caregivers. Positive and Negative Syndrome Scale (PANSS), modified Global Assessment of Functioning scale (mGAF), and Family Emotional Involvement and Criticism Scale (FEICS) were applied on the patients. Burden Assessment Schedule (BAS) was applied on the caregivers.

Results:

Patients were mostly male, symptomatic, diagnosed as paranoid schizophrenia and aged between 20 and 50 years. Caregivers were predominantly married and employed. Expressed emotions and burden of care were significantly related to caregiver and patient education, gender, employment, marital status, type of family, diagnosis, duration of illness, caregiver relation, duration of care giving, and severity of schizophrenia symptoms. Burden of care showed significant variations according to patient and caregiver economic status, domicile, religion, and age. Both expressed emotions and burden of care had moderately positive and statistically significant correlation with severity of the disease.

Conclusion:

Both expressed emotions and burden of care in primary caregiver of patients suffering from schizophrenia are influenced by a number of sociodemographic, clinical, and disease-related factors. Thus increase or decrease in expressed emotions and burden of care is caused by the complex interaction of various factors that the patients and caregivers experience.
Kemik Külü ve Uyumlaştırıcının PP/PA6 Matrisli Kompozitlerin Mekanik Özellikleri Üzerine Etkisi
Authors: ATABEK SAVAŞ Lemiye , UZUNOĞLU Yusuf , SAVAŞ Soner
Published: April 2022

Bu çalışmada, polipropilen (PP)/poliamid 6 (PA6) karışımlarında kullanılan kemik külü ve uyumlaştırıcı olarak maleik anhidrit aşılı polipropilen (MAPP) katkısının kompozitlerin mekanik ve ayrıca tribolojik özellikleri üzerindeki etkileri araştırılmıştır. Kemik tozu özellikle gıda sektöründe atık bir malzeme olarak karşımıza çıkmaktadır. Polimer matrisli kompozitlerde değerlendirilmesi petrol bazlı içeriğin azaltılması ve biyo-bozunur malzeme avantajı sunmasından dolayı önem arz etmektedir. Kompozitler ergiyik harmanlama yöntemi ile bir çift vidalı ekstrüder kullanılarak üretilmiş ve ardından enjeksiyon kalıplama ile mekanik ve tribolojik testlerde kullanılacak numune ölçülerine kalıplanmışlardır. Kompozitlere çekme testi, üç-nokta eğme testi, Shore D sertlik testi ve ball-on-disk kayma aşınma testleri uygulanmış ve sonuçlar kompozit bileşimine göre karşılaştırılmıştır. Sonuçlar incelendiğinde, kemik külü katkısının sertlik üzerinde, uyumlaştırıcı katkısının ise çekme ve eğme mukavemeti üzerinde daha etkili olduğu bulunmuştur. %20 ve %30 kemik külü katkısında en yüksek mekanik özelliklere ulaşılmıştır. Kemik külünün sürtünme katsayılarını düşürmede de çok etkili olduğu, özellikle uyumlaştırıcı ile birlikte kullanıldığında aşınma direncini önemli miktarda (%98’e kadar) azalttığı bulunmuştur. Özetle, kemik külü ve MAPP sinerjik etkisi ile elde edilen PP/PA6 matrisli kompozitler mekanik ve aşınma direnci gerektiren uygulamalar için ümit vadetmektedir.
CULTIVATING PRESCHOOL STUDENTS' DIGITAL COMPETENCE THROUGH DEVELOPMENTALLY APPROPRIATE SOFTWARE
Authors: Foti Paraskevi
Published: April 2022

Technology can be a powerful and engaging tool for collaborative and creative learning, helping students and teachers to access, create and share digital content, and express themselves creatively. In this paper, we will try to refer to the cultivation of digital competence from a very early age based on research data and the developmentally appropriate use of digital tools and software based on learning theories by presenting an indicative map of digital tool use in the classroom based on the European reference frameworks DeSeCo and DigComp Edu.
 

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HYPOTHYROIDISM IN THE PRACTICE OF A GENERAL PRACTITIONER
Authors: Timofeeva Natalya Yu. , Stomenskaya Irina S. , Kostrova Olga Yu.
Published: April 2022

Thyroid pathology is widespread and is detected in almost half of the population of the Chuvash Republic. The thyroid gland plays an important role in the functioning of many organs and systems in the human body. Thyroid hormones are vital for humans; they regulate water-electrolyte, protein, fat, carbohydrate and energy metabolism, normal functioning of organs and systems, including the central nervous system. One of thyroid gland pathologies associated with a deficiency of its hormones is hypothyroidism. Primary, secondary and tertiary hypothyroidisms are distinguished. Clinical manifestations of hypothyroidism are nonspecific, mostly they depend on the patient's age, duration and severity of hormone deficiency. Hypothyroidism is suspected if patients have the following symptoms: hypothermia, myxedemas due to accumulation of hyaluronic acid and mucin in the tissues, bradyphrenia, myopathy, anemia. Determining the level of TSH and free T4 in the serum helps to confirm it, and a thyrotrophin-releasing hormone test is used to diagnose secondary and tertiary hypothyroidism. The present article discusses a clinical case of hypothyroidism onset and the difficulties in diagnosing this pathology.
FORMATION AND EFFECTIVE USE OF FINANCIAL RESOURCES OF THE FEDERAL STATE STATISTICS SERVICE
Authors: Andreeva Natalia S. , Arkadeva Olga G.
Published: April 2022

Currently, the authorities act by managing financial resources, they are engaged in implementing state programs and national projects aimed at improving the efficiency of public funds spending, accelerating the country's economic development, stimulating the development of all economy sectors. The purpose of the study was to develop measures to improve the process of forming and using the financial resources of federal executive authorities on the example of the Federal State Statistics Service. The authors examined the theoretical aspects of organizing the federal executive authorities' finances, analyzed the process of forming and using the financial resources of federal executive authorities on the example of the Federal State Statistics Service, taking into account the specifics of activities in the conditions of the COVID-19 pandemic, they determined the problems and identified the main directions to improve the formation and the use of Rosstat's financial resources as one of the administrators of federal budget funds. The study resulted in the development of measures to improve the efficiency of financing and the use of authorities' financial resources, which can contribute to the augmented theoretical and practical foundation for the public sector functioning. The theoretical significance of the research lies in the development of economic and theoretical prerequisites for forming and using the financial resources by federal executive authorities, in identifying the patterns and directions of its development, determining the criteria and the ways to increase the efficiency of using federal budget funds. The practical significance of the study lies in the fact that its main results and recommendations regarding the formation and efficiency of using the financial resources can be applied in their activities by federal executive authorities with an extensive organizational structure.
MODERN METHODS OF PERSONNEL PROFESSIONAL TRAINING
Authors: Prokopiev Aleksandr V. , Chernysheva Tatiana N.
Published: April 2022

The article is devoted to the problem of personnel professional training in an organization. In modern conditions, an organization must quickly adapt to changing internal and external environment. The staff is the key element of the organization's internal environment and its ability to quickly learn and adapt to new conditions largely determines the success of the organization in a competitive market. When developing a long-term strategy, the organization should pay special attention to the professional training of its personnel, as this increases the guarantees that the organization is following the shaped plan. In the world, personnel’s training is comprehensive and systematic in nature using a variety of methods. The purpose of training is the staff's upgrade qualifications as well as related skills. In addition, training activates and stimulates the creative and innovative component of the employee's human potential, which contributes to his further career advancement. The methods of staff training are different and can have both individual and collective character. The management of the organization chooses the appropriate methods based on the current situation and the goals set, as well as the experience of conducting training. In the Russian practice domestic companies use modern training methods much less often than in foreign organizations. Such conservatism in approaches to training is often the result of an underdeveloped organizational culture and weak strategic planning, rather than a lack of financial and other opportunities. Staff training is an investment into the human potential that will be rewarded after a certain time, benefiting both the organization itself and its employees.
FACTORS OF COMPETITION CONDITIONS FORMATION IN THE NATIONAL ECONOMY UNDER THE INFLUENCE OF THE EXTERNAL ENVIRONMENT
Authors: Urusova Irina N.
Published: April 2022

The relevance of the research topic is conditioned by the fact that domestic manufacturers do not always successfully adapt to new conditions, using discretionary changes in external environment factors in a situation of sanctional confrontation. The immediate situation encourages the transition from a raw-material based economy and rent income orientation to deep processing production using all the links of value generation. In these conditions, it is necessary to deepen the knowledge that contributes to the use of the current situation in the markets to mobilize domestic producers. In assessing the opportunities of using the new situation, a number of misconceptions have developed concerning the conditions of the competitive environment in the markets, which are simplified in nature. Pursuant thereto, the article is aimed at in-depth understanding the process of formation of factors contributing to the transition to deep processing production, identification and justification of opportunities for creating a competitive advantage by domestic producers in order to ensure full import substitution. Competitive conditions that have developed as a result of discretionary changes in the external environment are examined on a systematic basis, in causal relationships applying various types of analysis, which ensures identification of those changes in the competitive environment of industrial markets that create favorable opportunities for the transition to the production of goods of deep, high-tech processing. In general, the results of the study can be used in the process of developing and implementing a strategy for the development of basic and life-supporting sectors of the domestic economy in conditions of instable distant external environment and sanctional confrontation with foreign trade and economic competitors.
STATE REGULATION OF FOREIGN TRADE ACTIVITY: METHODS AND THEIR LEGAL ESSENCE
Authors: Efimtseva Tatiana V. , Aliturliev Aslan S.
Published: April 2022

The authors carried out the analysis of current legislation of the Russian Federation and the Eurasian Economic Union, the practice of its application, the literature on the issue of state regulation of foreign trade activities. The concept of state regulation of foreign trade is given, the classification of these regulatory methods into types according to various criteria is presented. The Russian legislation contains an exhaustive list of methods for state regulation of foreign trade. However, application of specific methods depends on the type of goods. In connection therewith, the content of some of the most commonly used methods for state regulating foreign trade activity in practice is disclosed. At this, preference is given to the methods of customs tariff regulation, which include the customs tariff and customs duties. The relevance of the topic of state regulation of foreign trade is caused by the fact that foreign trade activity is currently becoming more and more colossal and covers all regions of the world, and therefore legal regulation of foreign trade is acquiring important socio-economic and sometimes political significance. So, in In January-August 2021, according to the data from the Bank of Russia, Russia's foreign trade turnover amounted to $492 billion dollars (137.8% by January-August 2020), including exports – $299 billion (144%), imports – $193 billion (129.2%). The trade balance remained positive, 106 billion US dollars (in January-August 2020 – positive, 58.3 billion dollars). Using the methods of observation, analysis, synthesis, comparison, interpretation of norms and others, the results were obtained that allow us to draw the following conclusions. When forming a foreign trade policy, the state needs to assess the regulatory impact on foreign trade in order to respond promptly to rapidly changing conditions in foreign markets functioning. Taking into account that the methods of state regulation of foreign trade activities are not systematized in the legislation, it is necessary to refer to the doctrine in which there is a classification of such methods into types. In addition, it is also necessary to take into account the fact that different methods of state regulation are applied to foreign trade in different goods.
Gilbert Sendromlu ve Hiperlipidemili Adolesan Hastada Aort Kapak Replasmanı
Authors: İŞTAR Hande , SEVUK Utkan
Published: April 2022

Gilbert Sendromu, bilirubinin kandan hepatositlere anormal şekilde up-take edilişi nedenli indirekt bilirubin düzeyinde ondülan yükselme görülmesidir. Aort darlığı, hiperlipidemi ve Gilbert Sendromu tanılı 16 yaşındaki erkek hastada kardiyopulmoner bypass eşliğinde yapılan mekanik aort kapak replasmanı, erken ve orta dönem postoperatif bulguları sunmaktayız.
Evde Sağlık Hizmeti Alanlara Bakım Verenlerin Yükü ve Stresle Başa Çıkma Durumlarının Değerlendirilmesi
Authors: ARSLAN Hatice Nilden , RENÇBER Emin
Published: April 2022

Bu çalışmada evde sağlık hizmeti alanlara bakım verenlerin yükü ve stresle başa çıkma durumlarının değerlendirilmesi amaçlanmıştır. Kesitsel tipteki araştırmada çalışma grubunu Samsun ilinde ikamet eden ve İl Sağlık Müdürlüğü Evde Sağlık Hizmetleri Biriminden hizmet alanlara bakım veren 156 kişi oluşturdu. Katılımcılara 01-30 Nisan 2018 tarihleri arasında yüz yüze görüşme yöntemiyle anket uygulandı. Araştırmacılar tarafından oluşturulan ankette sosyodemografik özellikleri içeren soruların yanı sıra, Zarit Bakım Veren Yükü Ölçeği (ZBVYÖ) ve Stresle Başa Çıkma Tarzları Ölçeği soruları yer almakta idi. Çalışmaya katılan bakım verenlerin yaş ortalamaları 50.8±10.2 yıl (min=23-maks=75), %90.4’ü kadın, %51.9’u ilkokul mezunu, %73.7’si evli ve %84.0’ü çocuk sahibiydi. Herhangi bir kronik bir hastalığı olanların sıklığı %66.0’ydı. Tam gün bakım verenlerde, bakıma yardım eden başka biri olmayanlarda ve kronik hastalığı olanlarda bakım verme yükü daha fazla iken, bakım verenlerin %14.7 si yükü olmadığını, %9.0’ı ise aşırı yükü olduğunu ifade etti. Bakım yükü ağır olanlarda kendine güvenli yaklaşım (p=0.024), iyimser yaklaşım ölçek puanları düşük (p=0.030), çaresiz yaklaşım ölçek puanı yüksek iken (p<0.001), sosyal desteğe başvurma (p=0.461) ve boyun eğici yaklaşım puanlarında fark bulunmadı (p=0.984). ZBVYÖ puanları ile kendine güvenli yaklaşım (r=-0.235, p=0.003) ve iyimser yaklaşım (r=-0.228, p=0.004) ölçek puanları arasında negatif yönde, zayıf, anlamlı ilişki varken, çaresiz yaklaşım (r=0.378, p<0.001) puanıyla pozitif yönde, orta düzeyde, anlamlı ilişki bulundu. Bakım verme süreci oldukça zorlayıcı bir süreçtir. Bu nedenle bakım verenler hem fizyolojik hem de psikolojik açıdan desteklenmelidir. Gerek toplumsal gerekse kurumsal desteğin bakım yükünü azaltmak için faydalı olacağı, ayrıca verilecek sosyal desteğin kişilerin stresle başa çıkmasını kolaylaştıracağı düşünülmektedir.
Tip 2 Diyabetes Mellitus’lu Hastalarda Kardiyopulmoner Egzersiz Testi ve Ekokardiyografik Parametrelerin Değerlendirilmesi
Authors: ASLAN Gamze , YILDIZ Ömer
Published: April 2022

Kardiyopulmoner egzersiz testi (KPET); genellikle kardiyovasküler, pulmoner ve kas-iskelet sistemlerinin egzersize yanıtlarının değerlendirilebildiği bir tetkik olarak kullanılmaktadır. Bu çalışmada, Tip2 DM hastalarında KPET ile ekokardiyografik bulguların ve ilişkilerinin değerlendirilmesi hedeflenmiştir. Tüm hastalara KPET ve transtorasik ekokardiyografi yapıldı. 30 kişi Tip2 DM grubuna (ortalama yaş 44.3±5.6 yıl), 20 sağlıklı kişi (ortalama yaş 42.2±3.5 yıl) ise kontrol grubuna alındı (p=0.141). Maksimal iş yükü (p=0.01), zirve VO2 (p=0.002), zirve VO2 tahmini (p=0.011), E/A (p=0.027) değerleri Tip2 DM grubunda kontrol grubuna göre anlamlı olarak daha düşük, VE/VCO2 eğimi (p=0.015) ise kontrol grubuna göre daha yüksek saptandı. Zirve VO2 değeri ile maksimal VO2 (r=0.49, p=0.001), maksimal iş yükü (r=0.72, p<0.001), egzersiz süresi (r=0.44, p=0.002) pozitif korelasyon gösterirken; sol ventrikül kitle indeksi (SVKİ) (r=-0.33, p=0.023), istirahat sistolik kan basıncı (r=-0.36, p=0.013), zirve sistolik kan basıncı (r=-0.32, p=0.029) ve zirve diastolik kan basıncı (r=-0.32, p=0.029) negatif korelasyon gösterdi. Zirve VO2 değerini etkileyebilecek yaş, SVEF, SVKİ, Tip2 DM varlığı parametrelerinin eklenmesiyle yapılan lineer regresyon analizinde, Tip2 DM varlığının (p=0.017) zirve VO2 değeri ile anlamlı ilişkisi olduğu bulundu. Çalışmamızda, Tip2 DM’li hastalarda kontrol grubuna göre KPET testinde zirve VO2 değerleri anlamlı olarak düşük bulunmuştur. Lineer regresyon analizinde de Tip2 DM varlığının zirve VO2 değerini bağımsız olarak etkileyebileceği yönünde veri elde edilmiştir. Bu hasta grubunda kardiyovasküler riskin belirlenmesinde yol gösterici olabilecek bu ilişkiyi daha net değerlendirmek için prospektif randomize kontrollü çalışmalara ihtiyaç vardır.
Coexistence of Axial Spondyloarthritis, Systemic Lupus Erythematosus, Sjögren’s Syndrome and Secondary Antiphospholipid Syndrome: Case Report
Authors: TARHAN Emine Figen , KESER Gökhan , İLHAN ÇELİK Özgür , KILINÇ Rabia Mihriban , KIRLI İsmail , AKAR Servet
Published: April 2022

Hereby we report a 55-year-old female patient having the association of non-radiographic axial spondyloarthritis (nr-AxSpA), systemic lupus erythematosus (SLE), secondary antiphospholipid antibody syndrome (APS), and Sjögren's Syndrome (SjS). Diagnosis of nr-AxSpA was made based upon the presence inflammatory low-back pain, human leukocyte antigen B27 positivity, and presence of sacroiliitis only in magnetic resonance imaging (MRI). SLE was diagnosed with butterfly-shaped rash on her cheeks, inflammatory arthritis, photosensitivity, erythema involving dorsal inter-joint area of hand fingers, alopecia together with antinuclear antibody (ANA) and anti-dsDNA positivity, low serum complement levels, leucopenia and thrombocytopenia. Additional presence of sicca symptoms, low Schirmer I test, anti SSA/Ro and anti-SSB/La positivity, supported by positive labial salivary gland biopsy led to the diagnosis of SjS. Furthermore, this patient also had miscarriage at 16th week and cerebral vascular disease at 33 years. Besides, IgG and IgM anticardiolipin antibodies were found to be positive twice. Therefore, she was also diagnosed as secondary APS. She fulfilled the relevant classification criteria for AxSpA, SLE, SjS and APS. To our knowledge, this is the first case report showing the association of these four diseases, with different genetic, etiopathogenetic and clinical systemic inflammatory diseases.
Interfaces entre o Ensino Híbrido e o Ensino de Ciências na Formação Docente
Authors: Marinho da Costa Cristiana
Published: April 2022

No cenário atual educacional, encontra-se o ensino híbrido denominado modelo de formação pelo qual se combinam atividades de ensino presenciais, com outras realizadas a distância e apoiadas em tecnologia da informação e comunicação (TIC). Sua finalidade é contribuir para alcançar os objetivos educacionais desejados a partir das vantagens que oferece cada ambiente. O processo de aprendizagem nessa modalidade, desenvolvido pelas metodologias ativas, remetem a práticas integralizadoras capazes de transpor os alunos do ambiente tradicional (sala de aula) a um lugar de tomada de decisões, experimentações e práticas significativas. Objetivamos compreender o formato de formação docente para o ensino híbrido e suas relações com o ensino de ciências. Trata-se de uma pesquisa qualitativa, na modalidade exploratória, desenvolvida a partir de produções atuais da área e aplicação de questionário sobre a temática com professores de ciências. Os resultados revelam que práticas de ensino na perspectiva das metodologias ativas propiciam motivação e curiosidade dos alunos sobre conhecimentos científicos, potencializando o engajamento nas tarefas. O objeto de estudo é fundamentado por autores como: Christensen, Horn, Staker, Valente, Moran entre outros. Ademais, o uso dessa prática propícia experiências formativas ao professor, desenvolvendo novas habilidades e construindo outros saberes para melhoraria de sua práxis educacional.