bluuebunny/crossref_metadata_2025 huggingface dataset:
Setting process on mortars containing sugarcane bagasse ash
Authors: CÂMARA E. , PINTO R. C. A. , ROCHA J. C.
Published: August 2016

Abstract This paper presents an experimental study of the effect of partially replace of fine aggregate by sugarcane bagasse ash (CBA) in mortar mixtures in cement reactivity at early ages. The setting times and the initial development of the ultrasonic velocity for mortars produced at various water/cement ratios were evaluated. The objective of this study was to characterize the effects of the partial replacement of fine aggregate by sugarcane bagasse ash in the initial process of cement hydration. Therefore, the CBA used in this study went through different beneficiation processes, by grinding, reburning and sieving, with the objective of improve its features. The results suggest the viability of CBA use to accelerate cement hydration at early ages, with also an observed higher compressive strength.
The response of buried pipes to UK standard traffic loading
Authors: Alzabeebee Saif , Chapman David , Jefferson Ian , Faramarzi Asaad
Published: August 2016

The current design practice in the UK for estimating the soil pressure on a buried pipe under traffic loads is based on a simple equation derived using a Boussinesq solution. In order to test and verify this equation, and study the effect of pipe diameter and backfill height for rigid (concrete) and flexible (polyvinyl chloride (PVC)) pipes, a study has been conducted using three-dimensional finite-element modelling. It was found that increasing the diameter of the concrete pipe non-linearly decreases the maximum vertical displacement, while the relationship between the concrete pipe diameter and the maximum thrust force was found to be dependent on the backfill height. Increasing the diameter of the PVC pipe linearly increases the displacement and the maximum thrust force. The effect of traffic live load on the maximum thrust force becomes insignificant for a cover depth larger than 2 m and 3 m for the concrete and PVC pipes, respectively. The results indicate that there are significant issues with the maximum soil pressure equation used in the British Standard. A new equation has been developed using numerical modelling results and employing a regression analysis to predict the maximum soil pressure on a buried pipe based on backfill height.
Influência do clima ético sobre o comprometimento organizacional dos servidores de uma universidade federal
Authors: Pereira Alexandre Severino , Cunha Cristianne Pereira , Pompeu Júlio Cesar
Published: August 2016

O objetivo deste estudo foi verificar se o clima ético influencia o comprometimento organizacional de servidores de uma universidade federal. Para tanto foi realizada uma pesquisa exploratória de abordagem quantitativa em que foi aplicado um questionário a 248 servidores. O instrumento foi formulado a partir de escalas internacionalmente reconhecidas e continha assertivas sobre clima ético e comprometimento organizacional. Os dados obtidos foram analisados com recursos de estatística descritiva e multivariada. A utilização da técnica de Análise Fatorial permitiu identificar quatro dimensões do clima ético e três dimensões do comprometimento organizacional. Os resultados obtidos com a aplicação da técnica de Regressão Múltipla confirmaram a influência do clima ético sobre o comprometimento organizacional. A dimensão “Suporte” do clima ético apresentou influência positiva sobre o componente “Afetivo” do comprometimento organizacional. O clima ético denominado “Regras, Leis e Códigos” afetou as dimensões “Afetiva” e “Calculativa” do comprometimento. Por sua vez o clima ético “Sucesso e Eficiência” mostrou-se um antecedente de influência positiva sobre o comprometimento “Normativo”.
Cocriação de valor no varejo através da utilização das mídias sociais
Authors: Santos Alessandra Thoms , Alves Lilian , Brambilla Flávio Régio
Published: August 2016

Este estudo objetivou compreender como as empresas de varejo cocriam com seus consumidores através das redes sociais. Utilizou-se um estudo exploratório-qualitativo, o qual foi conduzido por estudo de casos múltiplos com três empresas do varejo da cidade de Santa Cruz do Sul, RS. A técnica utilizada para coleta de dados foi entrevista semiestruturada. Analisou-se que as empresas pesquisadas utilizam-se das redes sociais para cocriar valor com seus clientes, cada uma das três empresas com o seu público-alvo e estratégias específicas. Porém, estão cientes que o consumidor está presente nas mídias sociais e que o varejo precisa se adaptar a essas ferramentas. Os resultados evidenciam a importância em manter relacionamentos próximos com os consumidores mesmo que o processo seja online.
Engajamento cidadão e processos decisórios: abordagem a partir do federalismo brasileiro
Authors: Gandra Pimenta Magalhães Fernanda Gabriela , De Almeida Mendes Wesley , Marques Ferreira Marco Aurélio , Silva Edson Arlindo
Published: August 2016

Com a recente descentralização político-administrativa no Brasil e abertura à participação, surgem mecanismos que marcam uma nova Era na relação entre Estado e sociedade. Este artigo objetiva analisar de que forma o federalismo oportuniza a participação popular, colocando em pauta os orçamentos participativos. Constatou-se que esse contexto possibilita participação popular, assim como o controle e aplicação de políticas públicas, destacando que o orçamento participativo tem se mostrado importante instrumento de minimização de desigualdades e desequilíbrio de acesso ao poder decisório. Por fim notou-se que o federalismo ainda não oferece garantias plenas para efetivação da participação, sendo necessário pôr em prática meios que viabilizem a democratização do processo de formulação e controle de políticas públicas.
Reforming the South African Social Security Adjudication System: Innovative Experiences from South African Non-Social Security Jurisdictions
Authors: Nyenti Mathias Ashu Tako
Published: August 2016

There is currently no uniform social security dispute resolution system in South Africa due to the piecemeal fashion in which schemes were established or protection against individual risks regulated. The result is that each statute provides for its own dispute resolution institution(s) and processes. There are also various gaps and challenges in the current social security dispute resolution systems, some of these relating to the uncoordinated and fragmented nature of the system; inaccessibility of some social security institutions; inappropriateness of some current appeal institutions; the lack of a systematic approach in establishing appeal institutions; a limited scope of jurisdiction and powers of adjudication institutions; inconsistencies in review and/or appeal provisions in various laws; an unavailability of alternative dispute resolution procedures; and an absence of institutional independence of adjudication institutions or forums. The system is therefore in need of reform. In developing an appropriate system, much can be learned from innovative experiences in comparative South African non-social security jurisdictions on the establishment of effective and efficient dispute resolution frameworks. Dispute resolution systems in the labour relations, business competition regulation and consumer protection jurisdictions have been established to realise the constitutional rights of their users (especially the rights of access to justice, to a fair trial and to just administrative action). They thus provide a benchmark for the development of the South African social security dispute resolution system.
Conscription, Citizenship, and French Algeria
Authors: Pine Savannah
Published: August 2016

This paper questions why the Third Republic of France imposed conscription on Muslim Algerians in 1912. This action is peculiar because conscription was a tenant of French citizenship, which the French thought that Muslim Algerians were too inferior to have. A politician named Adolphe Messimy, the members of the Third Republic in control of the government in 1912, and a group called the Young Algerians convinced France to contradict its laws and beliefs to impose conscription. They did so because the self-interests of all three groups met at one moment in time and wanted conscription. This paper meticulously explains the motives of Adolphe Messimy, the Third Republic, and the Young Algerians to explain why each agreed to conscription. This research fits into the broader schematic of French Algerian history because it argues that Algeria, in part, gained its independence in 1962 due to the imposition of conscription in 1912.
Disaster’s Face
Authors: Sanders Trent
Published: August 2016

The global mass media in general depicts disasters as a spectacle for an audience of consumers. As a result, the individuals depicted effectively become generic victims, not fully developed human beings with distinct needs and interests (Drake, Tierney). In Sinha’s novel, however, the chemical plant explosion, though drastically noxious to Khaufpuri citizens, is not restricted to harming only Khaufpuris. In fact, Animal’s narrative conveys visual punctual violence on a Western audience, as well as the Khaufpuris. He reminds his Western audience that there are exposed human bodies in specific geographic locations. This essay investigates the corporeal experience Animal’s audience has with disaster because of his narrative style. I argue that Animal’s People rhetorically constructs a Western audience, and in doing so, reorients the Western audience’s relationship with disaster and disaster victims. Put another way, this essay argues that Sinha’s novel discloses both non-Western and Western human beings amidst catastrophe by deconstructing the fantasy that Westerners are far removed and invincible from disaster.
ESP PRACTITIONERS’ ROLE AND THEIR ETHNOGRAPHY: A CASE STUDY OF ESP PRACTITIONERS AT THE INDONESIAN TERTIARY LEVEL
Authors: Muhrofi-Gunadi Kun Aniroh
Published: August 2016

This current research aims at revealing factual ESP practitioners’ roles at the tertiary level of education in Malang City, Indonesia. Data were collected through semi-structured interviews and a survey using questionnaires involving 22 ESP practitioners selected randomly from several universities and colleges in Malang. To collect data on the roles of ESP practitioners, the present study adopted two sources in the questionnaires: First, the roles of ESP instructors as teachers, course designers, materials providers, researchers, and evaluators as proposed by Dudley-Evans and St. John (1998), and secondly as a practitioner who has intercultural competence and professional activity competence as defined by Luka (2004) and ethnography (Wall, 2014). The findings showed that the majority (70%) of ESP practitioners realized their roles and some (30%) claimed to learn more on mastering contents, providing materials, conducting research on needs analysis, learning intercultural competence, and realizing the needs to have experiences in industries or related work places of the students. Concerning their ethnography, the majority of ESP practitioners did not have the opportunity to teach, to have internship, and to work in industries. Only 2 (9.1%) ESP practitioners studied the field of what students learn. Future research on the collaboration between academics and practitioners is needed to make ESP classrooms a ‘real world’.
ATTITUDES AND EXPERIENCES OF CLASSROOM SCIENCE: CHILDREN’S VOICES
Authors: Ward Gillian , Donnan Lauren E , McNabb Kirsten
Published: August 2016

This article draws on two studies that examined primary children’s attitudes towards science in the classroom and their experiences of science. Through the data drawn from semi-structured interviews, it was evident that the children were mostly positive about science, but their experiences of science in the classroom were not always how they would prefer their science learning to proceed. The findings highlight aspects of their experiences that enhanced or detracted from their interest in science. In particular, the students stated the importance of being taught relevant and meaningful science in a collaborative context. Children’s out-of-school contexts also became important in their learning of science. These findings are discussed, and suggestions are made for ways in which teachers can make changes to their planning and teaching in order to support positive attitudes to science within the classroom.
THE EFFECTIVENESS OF COLLOID MODULE BASED ON GUIDED INQUIRY APPROACH TO INCREASE STUDENTS’ COGNITIVE LEARNING OUTCOMES
Authors: Novilia Lita , Iskandar Srini M. , Fajaroh Fauziatul
Published: August 2016

Colloid is one of the chemical topics taught in high school. Actually, the characteristic of Colloid topic is contextual. Colloid topic is taught by expository and discussion methods. Based on observations in SMA Negeri 4 Malang and SMA Negeri 16 Surabaya, these methods could not improve students’ ability to construct their own knowledge; as a result, students did not have a good understanding in the Colloid topic. An alternative way to increase students’ understanding, especially in the cognitive aspect is using innovative teaching materials like a colloid module based on guided inquiry approach. The previously mentioned module was developed by the author. The feasibility percentage of the Module was 85.66%. The aim of this research is to find the effectiveness of the Colloid Module to increase students’ cognitive learning outcomes. This research used one group pretest-posttest experimental design. The sample of this research consisted of 33 students of X-MIPA 3 SMA Negeri 2 Malang in the 2015/2016 academic year. The effectiveness of The Colloid Module to increase cognitive learning outcomes was determined by the results of paired sample t-test analysis and the gain score of students’ pretest and posttest using cognitive test instrument. This cognitive test instrument had content validity index of 92.04%. Based on the trial result of 36 students in SMA Negeri 3 Malang, 30 questions were considered valid and had a reliability coefficient of 0.866 based on Spearman-Brown. The result of this research showed that the Colloid Module was effective to increase students’ cognitive learning outcomes. It was indicated by the analysis of paired sample t-test, with t score (-38.525) lower than t critical (-2.037), so there was a significant difference between pretest and posttest scores after using the Colloid Module. The effectiveness of the Colloid Module was also determined by the gain score of pretest and posttest scores of students’ cognitive skills of 0.688, categorized as a medium gain.
COOPERATIVE PRINCIPLE OF CONVERSATIONS IN VIKRAM SETH’S A SUITABLE BOY: A SOCIO-PRAGMATIC ASSESSMENT OF INFERENTIAL CHAINS OF INTERPRETATION
Authors: Thakur Vijay Singh
Published: August 2016

Grice (1975) provides an interpretative model that explains how we draw inferences from conversation. This theory of Cooperative Principle (CP), based on the philosophical ideas of Grice, relates the text to its contexts, including social context. As Schiffrin (1994) remarks, the application of CP to dialogic conversations leads to a particular view of discourse and its analysis, i.e. discourse as a text whose contexts (including cognitive, social and linguistic contexts) allow the interpretation of real speaker meaning in utterances (p. 227). The approach that Gricean Pragmatics offers to discourse analysis is based on a set of general principles about rationally-oriented communicative conduct that tells speakers and hearers how to organize and use information offered in a text, along with background knowledge of the world (including knowledge of the immediate social context), to convey (and understand) more than what is said– put simply, to communicate. In this paper, I am going to focus on and explore how we understand fictional discourse using pragmatic interpretative strategies to reconstruct inferential chains which lead us to a particular interpretation of conversation. I will discuss various issues of inferences, generated via Grice’s model, in the interpersonal pragmatics involved in the character utterances in Vikram Seth’s A Suitable Boy. The paper attempts to demonstrate how pragmatic interpretative strategies can make an added contribution to the study of literature as well as to the development of pragmatic competence, critical thinking, and better understanding of the use of naturally occurring language, both in literature and language classrooms.
Кафедра истории Московского гуманитарного университета
Authors: Алексеев Сергей Викторович
Published: August 2016

Очерк истории и основных направлений научно-исследовательской деятельности кафедры истории Московского гуманитарного университета. Подготовлено на основе доклада автора на Всероссийской научной конференции «Военная история России», которая прошла в Московском гуманитарном университете 25 апреля 2016 г.
Десять тезисов о войне как способе решения человеческих конфликтов
Authors: Королев Анатолий Акимович
Published: August 2016

В статье характеризуются основные черты войны как способа решения человеческих конфликтов. Подготовлено на основе доклада автора на Всероссийской научной конференции «Военная история России», которая прошла в Московском гуманитарном университете 25 апреля 2016 г.
О причинах похода русских князей на половцев в 1103 году
Authors: Инков Александр Александрович
Published: August 2016

Статья посвящена рассмотрению причин первого крупного похода русских князей против половцев в1103 г.

Подготовлено на основе доклада автора на Всероссийской научной конференции «Военная история России», которая прошла в Московском гуманитарном университете 25 апреля2016 г.
«Человек войны» в контексте военной истории Крыма 1941–1944 гг., или Оборона Севастополя — история защищающихся
Authors: Жукова Ольга Германовна
Published: August 2016

Статья посвящена военной истории Крыма, в частности, обороне Севастополя в годы Великой Отечественной войны. Автор отмечает важность историософского осмысления истории Великой Отечественной войны.

Подготовлено на основе доклада автора на Всероссийской научной конференции «Военная история России», которая прошла в Московском гуманитарном университете 25 апреля 2016 г.
«Летающие гробы»? К вопросу об использовании древесины в советском самолетостроении в период Великой Отечественной войны
Authors: Шерстюк Максим Витальевич
Published: August 2016

В статье рассматриваются некоторые проблемы отечественного самолетостроения в годы Великой Отечественной войны. Называются причины и обоснованность использования в авиастроении заменителей металла: древесины и тканей; проводится сравнение с аналогичной практикой зарубежных стран.

Подготовлено на основе доклада автора на Всероссийской научной конференции «Военная история России», которая прошла в Московском гуманитарном университете 25 апреля 2016 г.
Algunas reflexiones en torno al fotoperiodismo y la dictadura en la historiografía argentina reciente
Authors: Del Castillo Troncoso Alberto
Published: August 2016

El fotoperiodismo es un espacio fundamental para el estudio de relación entre la imagen y la elaboración de una memoria colectiva en torno a los años de la última dictadura argentina en los espacios públicos. En este artículo se analiza una parte importante de la investigación de Cora Gamarnik, autora de diversos artículos emblemáticos sobre el tema. Se destacan las premisas conceptuales y la crítica de fuentes que subyace en sus aportaciones, y se discuten las bases de la lectura de imagen en torno a uno de los episodios más relevantes de la historia reciente latinoamericana.

 

 
Fabián Herrero, “Capusotto cenador, Alberti almorzador” Sobre la política y el “voto bronca” en los comicios nacionales: Argentina, 2001, Rosario, Prohistoria Ediciones, 2012, 232 páginas.
Authors: Blogna Tistuzza Sergio
Published: August 2016

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AMOR Vol. 2, Issue 4, 2016
Authors: Office Editorial
Published: August 2016

View the full issue here.
Astigmatism Correction in Cataract Surgery with Foldable Toric IOL
Authors: Patil Mrunal Suresh , Balwir Dhiraj Namdeo , Dua Sonal , Vidhate Swapnil Shivaji
Published: August 2016

Aim: To evaluate correction of pre-existing astigmatism after foldable Toric IOL implantation in patients undergoing cataract surgery.

Materal & Methods: In this prospective observational study we included 10 eyes of 10 patients with astigmatism between 2.00D to 6.00D &undergoing cataract surgery. Phacoemulsification was performed with Toric IOL implantation through 2.8mm clear corneal temporal incision. Patients were examined post operatively for Uncorrected Visual Acuity (UCVA), Best Corrected Visual Acuity (BCVA) & residual refractive astigmatism.

Statistical Analysis: Statistical analysis was performed by the SPSS program for Windows, ver.16.0.Continuous variables are expressed as mean ± SD, and categorical variables are presented as absolute numbers and percentage. For the statistical test, a p value less than 0.05 was taken to indicate a significant difference.

Results: The UCVA was 6/9 or better in 90% of eyes. 80% eyes achieved 6/6 BCVA. The mean refractive cylinder corrected from -3.4 ± 1.4 D to -0.60 ± 0.27 D which was statistically significant. (p value=0.0001).

Conclusion: Toric IOL implantation is an effective, safe surgical option to manage pre-existing corneal astigmatism during cataract surgery.
To Study Bacteriological Profile and Antibiotic Sensitivity Pattern in Cases of Neonatal Sepsis
Authors: Sonawane Sagar , Tolani M. K. , Suryawanshi Milind , Patil Priyanka
Published: August 2016

Objective: To study the bacteriological profile and sensitivity pattern in cases of Neonatal sepsis at 12 bedded Neonatal Intensive Care Unit (NICU). Methods: This was a prospective study of neonates admitted to our NICU from Jan 2010 to Oct 2011 with diagnosis of neonatal sepsis or those who developed sepsis later during their stay in NICU. All newborns diagnosed as a case of neonatal sepsis, based on clinical features with positive sepsis screen and/or positive blood culture, were included in our study. Blood Culture&Sensitivity was done with conventional non-automated method using Herley's Broth. Results: Out of 55 cases blood culture was positive in 27 (49.09%) cases. Klebsiella Pneumoniae 15 (55.55%) was the most common organism isolated in both early and late onset sepsis showed sensitivity to collistin in 86.6% of cases followed by sensitivity to imipenam-cilastin in 46.67% cases. Only 20% Klebsiella isolates were sensitive to drugs like Ampicillin-sulbactum, Amikacin, Tazobactum, cefpime and for other antibiotics like Meropenam, Piperacillin-tazobactum, Vancomycin it was less than 20%. Other organisms isolated were Staph. aureus, E. Coli, Pseudomonas, Enterobactor, Acinetobactor and candida species. Conclusion: Gram negative organisms are most common cause of early as well as late onset sepsis and there is alarming degree of antibiotic resistance to commonly used antibiotics.
Study of Psychiatric Morbidity in Infertile Women
Authors: Sule Rucha , Gupte Sunil G.
Published: August 2016

Context: The WHO estimates that 8-12% of couples around the world experience difficulty conceiving a child. The impact of infertility on the psychological well being of couples involved has been the object of increasing attention in recent years. Most of the studies which have been conducted to identify the psychopathologies of infertile women have focussed their attention on depression and anxiety. Aim: The aim of the present study was to identify the prevalence of psychiatric disturbances in women suffering from infertility. Settings and Design: A cross sectional study was conducted in the Outpatient departments of Psychiatry and Obstetrics&Gynaecology. Methods and Material: One hundred and twenty infertile women were selected. They were interviewed using a special proforma and screened using Mini -international Neuropsychiatry interview English Version 6.0.0 Statistical Analysis Used: The data was analysed using SPSS version 19 &s EPI INFO software. Results: Psychopathology was found in 39.16% of the study population. Depression was the most common psychiatric morbidity found followed by generalized anxiety disorder. Conclusion: Infertile women should be routinely evaluated for psychological disturbances and psychiatric morbidity to maximise their health.
Preparation of Blue Prints for formative Theory Assessment of Undergraduate Medical Students in Community Medicine
Authors: Gujarathi Amit P. , Dhakne-Palwe Supriya , Patil Rakesh N. , Borade-Gedam Pratima , Mahale Mahesh S. , Gosavi Shriram V. , Vankudre Ashok J. , Almale Balaji D. , Pawar-Bhalerao Sunita
Published: August 2016

The written assessment of medical students is very important in view of assessing the various levels of cognitive domains. The validity of any assessment depends upon the appropriate constriction of assessment tool. Framing an ideal theory assessment tool that covers the whole syllabus with proportionate weightage to various content areas according to their importance is big challenge for the paper setter. Considering the vast nature of Community Medicine syllabus constructing a theory assessment tool as per above said ideals is still more difficult. Blueprinting of syllabus i.e. covering all the content areas with allocating proportionate weightage to various content areas can overcome this issue and helps the paper setter to construct a uniform and valid assessment tool. Department of Community medicine has constructed such two blue prints that can be used for either formative or summative type of theory examination.
Study of Diagnostic Importance of Adenosine Deaminase (ADA) Level in Pleural Effusions
Authors: Kate Sachin , Mutha B. K. , Kulkarni Gauri , Mahajan Chetan , Dugad Sushma
Published: August 2016

Introduction: Pleural effusion is the abnormal accumulation of fluid in the pleural space. TB is the most common cause of pleural effusion worldwide (30-60%). The pleural fluid activity of adenosine deaminase (ADA) is one of the best, providing reliable basis for a treatment decision, particularly in excluding the diagnosis of tuberculosis, due to its high sensitivity. Aims and Objectives: To assess the importance of adenosine deaminase(ADA) level in the diagnosis of pleural effusion. To assess Adenosine Deaminase Activity (ADA) in tuberculosis pleural effusion and assess the sensitivity and specificity of ADA levels. Materials and Methods: This study was performed at the Department of Pulmonary Medicine at tertiary care centre. The study comprised of 75 patients of pleural effusion having Age > 14 years, Clinical and Radiological evidence of Pleural Effusions&Patients willing for ADA examination. Patients having Age > 65 years, minimal nontappable effusion, not giving consent for ADA examination patient were excluded from the study. Detailed history, thorough physical examination, radiological findings, haematological and biochemical findings were recorded in the proforma. Pleural aspiration was performed on all patients. Macroscopic findings, cytological, microbiological and biochemical analysis of pleural fluid were performed in all patients including ADA level. PCR for Mycobacterium tuberculosis was also assessed in pleural fluid. Pleural fluid Adenosine deaminase level was measured by Giusti and Galanti method. Result: In our study out of 45 patients with tuberculosis pleural effusion ADA was more than 40IU/L in 42 (93.33%) and less than40IU/L in 3 (6.66 %). Our study showed a mean ADA of 107.7 IU/L Using a cut off of greater 40IU/L we got a sensitivity and specificity of 93.3% and 90% respectively and Positive predictive value 93.3% and Negative predictive value 90%. Conclusion: Pleural fluid ADA activity has been shown to be a valuable biochemical marker that has a high sensitivity and specificity for TB diagnosis.
Gaucher's Disease - A case report
Authors: Bajaj Preeti , Kasture Jyoti , Shah Balbir Singh
Published: August 2016

Gaucher's Disease (GD) is an autosomal recessive systemic lysosomal storage disorder which is characterized by glucocerebroside deposition in cells of the macrophage-monocyte system as a result of a deficiency in lysosomal P-glycosidase (glucocerebrosidase). GD is a rare genetic disorder. It is the most common amongst the lysosomal storage disorders. GD has been categorised into three types based on the presence of central nervous involvement1. Type 1 is a non-neuronopathic form that presents in childhood or early adulthood. Type 2 is acute neuronopathic form that presents in childhood. It progresses rapidly and is fatal. Type 3 is chronic non-neuronopathic form that presents in childhood but is slowly progressive. Here we describe a case of a three and a half year old male child in whom a diagnosis of Gaucher's disease was made based on bone marrow biopsy and later confirmed by glucocerebrosidase levels estimation.
Study of Correlation of Cord Blood Bilirubin with Neonatal Hyperbilirubinemia
Authors: Ahire Nilesh , Sonawane Ravindra , Gaikwad Rajendra , Patil Suhas , Sonawane Tushar
Published: August 2016

Introduction: Neonatal Hyperbilirubinemia (NH) is a universal problem affecting nearly 60% of term and 80% of preterm neonates during first week of life. Early discharge of healthy term newborns is a common practice because of medical, social and economic constraints. Insignificant number (6.5%) of babies, NH is a cause for readmission. The present study was conducted to correlate the Cord Blood Bilirubin (CBB) level with subsequent NH. Methods: Study was performed at the Department of Pediatrics in a Medical College Hospital and Research Centre. Intramurally delivered, 113 Healthy full-term newborns during 1-year period were prospectively enrolled. CBB was estimated. Serum Bilirubin estimation was done at 48 hours and 5 day of age and later if required. Results: Significant NH in our study is 3.5%. Mean total bilirubin on second postnatal day was 10.58 mg/dl and on fifth post natal day was 10.81 mg/dl. Using CBB level of ≥3 mg/dl as a cut-off, NH can be predicted with sensitivity of 100%, specificity of 98.17%, positive predictive value of 66.67% and negative predictive value of 100%. Conclusion: A 100% Negative Predictive Value in the present study suggests that in Healthy Term babies (without RH and ABO incompatibility with Cord Blood Bilirubin ≤3mg/dl) cord serum bilirubin can help to identify those newborns who are unlikely to require further evaluation and intervention. These newborns can be discharged with assurance to Parents. Babies with CBB level ≥3mg/dl should be followed more frequently.
Cytological Profile of Thyroid Lesions and it's Correlation with Clinical and Ultrasonography Findings
Authors: Chavan Ujwala S. , Patil Archana , Mahajan Suresh V.
Published: August 2016

Background: Thyroid gland is the first endocrine gland to develop, largest of all endocrine glands. Superficial location of thyroid gland allows evaluation of thyroid lesions by FNAC (fine needle aspiration cytology). Aims and Objective: To study cytological profile of thyroid lesions and correlate the results with Ultrasonography findings and clinical features. Material and Methods: This prospective study was carried out on 138 patients who came to the department from period of May 2012 to December 2014. Out of these 138 patients USG was carried out in 115 patients. FNAC of patients was performed and results of FNAC were correlated with those of USG reports and clinical features of the patient. Results: Out of 138 cases 83 (60.1%) cases were benign, 18(13.0%) cases were inflammatory, 2 (1.4%) cases were malignant, 28 (20.3%) were categorised as indeterminate, and 7 (5.1%) cases were inadequate. All the 2 malignant cases were given as neoplastic on USG. Conclusion: FNAC is the main diagnostic modality of choice for thyroid lesions, along with Ultrasonography and clinical examination it helps to come to the proper diagnosis.
Особенности конфликтов
Authors: Оболонский Александр Юрьевич
Published: August 2016

Справедливо считается, что результативность деятельности и конкурентоспособность любой организации зависит от эффективности управления. Управленческая деятельность является одной из самых сложных видов профессиональной деятельности. В то же время, как и любая предметная деятельность, она имеет устойчивую психологическую структуру, включающую ряд психологических составляющих.
Авторефлексия и самопознание
Authors: Анисимов Олег Сергеевич
Published: August 2016

Каждый человек согласится, что познание себя осуществляется в течение всей жизни. Одни люди не замечают прирост знаний о себе и даже сам процесс дополнительного познавания. Другие –обращают внимание на процесс дополнительного познания себя.
Проблемы традиционного обучающего консультирования
Authors: Верхоглазенко Владимир Николаевич
Published: August 2016

Любые изменения нормативного устройства предприятия требуют персонал с соответствующей квалификацией, способный адекватно выполнять измененные нормы. В связи с этим возникает вопрос об обучающем консультировании.
Проблемы психологической депривации инженеров-энергетиков, работающих вахтовым методом
Authors: Фомин Николай Вячеславович , Козьяков Роман Валерьевич
Published: August 2016

Регуляция психического состояния такого специалиста, как инженер-энергетик, работающего вахтовым методом, — важная и актуальная проблема современной психологии, поскольку нарушения в состоянии неизбежно влекут за собой сбои в работе вследствие утомления, неправильного режима труда и отдыха и т.д. Психологическая депривация, тревога, депрессия, страхи и др. также относятся к последствиям влияния особых условий, в которых осуществляется работа инженеров-энергетиков, а также влияния специфики вахтового метода в целом.
Conference 2016: From Drug Discovery to Health Outcomes: Population to Patient. An international symposium held jointly by CSPS and CC-CRS, May 31-June 3, 2016, Vancouver, BC, Canada
Authors: Berekoff Beverley
Published: August 2016

Plenaries and Special Presentations:Carolyn Buser-Doepner, GSK:  "New Trends in Pharma-Academia Collaborations for Drug Discovery"Chris Halyk, President, Janssen Inc.:  "Are Innovative Medicines and our Life Sciences Industry at Risk in Canada?"Aaron Schimmer, Princess Margaret Cancer Centre:  "New Therapeutic Strategies to Target the Mitochondria in Leukemia"Ivana Cecic, Genome BC:  "Genomics in Canada: From Knowledge Generation to Patient Outcomes"Adam Rosebrock, University of Toronto:  "Quantitative Mass-Spectrometry Metabolomics for Direct Biochemical Phenotyping"Fakhreddin Jamali, University of Alberta: CSPS Lifetime Achievement Award Lecture - "Pharmaceutical Research and Development, Lessons Learned"Conference Sessions:Special Session: Innovation and Management of Modern Pharmaceuticals1. Special Populations2. Nanomedicines Become Personal: Opportunities and Challenges3. Mucosal Drug Delivery4. Broaching the Fourth Hurdle: Getting Drugs on the Formulary5. Pharmacogenomics in the Clinic and Community6. Responsive Drug Delivery Systems7. Drug Targeting and Targeting Drugs8. Health Sustainability Evidence9. Integrating Pharmaceutical Sciences into a Pharm D Curriculum10. Analytical Innovation to Support Precision Medicine and Biologicals Development11. Protein and Peptide Delivery
Microdialysis-directed Intra-tumor Pharmacokinetic Modeling of Methotrexate in Mice and Humans
Authors: Alsulimani Helal H. , Kim Jonghan , Sani Shabnam N.
Published: August 2016

Purpose. To develop a quantitative pharmacokinetic model to characterize the disposition of methotrexate (MTX) at tumor site in tumor-bearing mice and to predict MTX concentrations in the human tumor. Methods. The plasma profiles of MTX were obtained from normal mice, while microdialysis technique was employed to characterize the time course of MTX in tumor from breast tumor-bearing mice. Disposition profiles of plasma and tumor were analyzed by a hybrid physiologically-based pharmacokinetic (hPBPK) model that incorporates physiologically-relevant parameters such as tumor blood flow and volume, while plasma concentrations were used as a forcing input into the vascular-interstitial spaces of the tumor. The plasma profiles were initially described by a biexponential decay model to obtain a forcing function that enters into the vascular-interstitial spaces in the tumor. Using a defined forcing function, the tumor free concentrations were fitted to the hPBPK model. Based on the model developed, sensitivity analysis was conducted with a perturbation of PK parameters to predict different scenarios of intratumoral MTX transport. The relevant physiological PK parameters from the mouse model were then scaled-up and utilized to simulate human tumor concentrations. Results. The mouse hPBPK model adequately characterized the concentration-time profiles of MTX in both plasma and tumor and produced various transfer rate constants between plasma and tumor. Our model was also able to reasonably predict MTX concentrations in the human tumor when human physiological data were utilized. Conclusions. The hPBPK model was able to quantitatively characterize the atypical transport of MTX in the tumor, supporting the idea that microdialysis is a valuable tool to study tumor biodistribution of drugs and to predict tumor concentrations in humans based on the pre-clinical data. This information can ultimately aid in the development of anticancer drugs with improved PK profiles. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
Organogels in Drug Delivery: A Special Emphasis on Pluronic Lecithin Organogels
Authors: Alsaab Hashem , Bonam Sindhu Prabha , Bahl Dherya , Chowdhury Pallabita , Alexander Kenneth , Boddu Sai HS.
Published: August 2016

Organogels have emerged as an alternative carrier for small and macromolecules via transdermal, oral, rectal and ophthalmic routes. Pluronic lecithin organogels (PLO gels) are lecithin-based organogels widely used in compounding pharmacies as a vehicle for enhancing the transdermal permeability of many therapeutic drugs. However, the scientific and systematic evidence in support of how well PLO gels help in transdermal delivery is scanty. Recently, some clinical studies have reported nearly complete lack of bioavailability of certain topically administered drugs from PLO gels. The present review aims at summarizing gels and organogels, with a focus on the use of PLO gels in transdermal drug delivery. A special emphasis is placed on controversies looming over the use of PLO gels as a delivery platform for drugs via transdermal route. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
Primeros frutos en la lucha contra la corrupción en Costa Rica: condenatoria en sede penal por delitos tipificados por la Ley contra la corrupción
Authors: Arroyo Chacón Jennifer Isabel
Published: August 2016

El presente documento pretende analizar y compartir una de las primeras experiencias generadas en la lucha contra la corrupción en la función pública costarricense, luego de la aprobación de la Ley contra la corrupción y el enriquecimiento ilícito en la función pública en ese país. Para comprender el caso, se inicia con un segmento de antecedentes de la lucha contra la corrupción en Costa Rica, citando tanto los instrumentos jurídicos internacionales y nacionales como las instituciones sobre quienes se les ha delegado esa función. Posteriormente, se explica la tipificación de los delitos analizados en el caso en discusión, con el fin de que el lector comprenda el marco jurídico vigente en el momento en que ocurrieron los hechos. Finalmente, se realiza un análisis profundo de la sentencia de la Sala Tercera de la Corte Suprema de Justicia que avala la condenatoria de los imputados por los delitos de corrupción en la función pública, con una descripción detallada de cada tipo penal y el razonamiento jurídico expuesto por el Tribunal en su sentencia, elemento enriquecedor de la discusión de la lucha contra la corrupción en la función pública. Termina el texto destacando la importancia de este primer precedente en la lucha contra la corrupción en la función pública e invita a seguir su ejemplo.
Pizarro Meets Atahualpa Again
Authors: Dabydeen Cyril
Published: August 2016

Poem
Cosmic Dance
Authors: Dabydeen Cyril
Published: August 2016

Poem
Impact of PGRS and nutrients pre-soaking on seed germination and seedling characters of mung bean under salt stress
Authors: Sivakumar* R. , Nandhitha G. K.
Published: August 2016

An experiment was conducted to study the impact of seed soaking with plant growth regulators (gibberellic acid, indole acetic acid, kinetin, salicylic acid and ascorbic acid) and nutrients (potassium chloride and calcium chloride) on mung bean (Vigna radiata L.) variety Co (Gg) 8 under salt stress condition. The seed and seedling growth under normal and saline (150 mM NaCl) conditions were studied to determine their usefulness in increasing relative salt tolerance by using PGRs and nutrients. Under salt stress, seedling characters were significantly affected compared to normal condition. Seed treatments with gibberellic acid (1mM), salicylic acid (2 mM), ascorbic acid (50 ppm) and kinetin (50 ppm) drastically increased the morphological and biochemical parameters of seedling under saline conditions. All pre-soaking seed treatments increased the germination percentage, shoot and root length, vigour index and stress tolerance index over control. Among the treatments, gibberellic acid, salicylic acid and ascorbic acid showed their supremacy compared to other treatments. Na+ / K+ ratio was decreased by gibberellic acid, CaCl2 (0.5%) and KCl (1%) treatments. It is concluded that treatments with hormones and nutrients have reduced the severity of the salinity effect and the amelioration was observed in all the treatments compare to control. Gibberellic acid and salicylic acid and ascorbic acid showed best results on seedling growth and biochemical characters whereas seed soaking with gibberellic acid, CaCl2 (0.5%) and KCl (1%) were showed its effect on decreased Na+ / K+ ratio under present experimental material and saline conditions.
Effect of foliar application of growth activator, promoter and antioxidant on seed quality of soybean
Authors: Kuchlan* P. , Kuchlan M.K. , Husain S.M.
Published: August 2016

Loss of seed quality in soybean is a serious problem in tropical and subtropical region. Foliar application of salicylic acid (SA), GA3 and acetyl salicylic acid (50 ppm) at seedling and pod filling stage, K2HPO4 (2%), a-tocopherol (100 ppm) at flowering and pod filling stage was done on soybean varieties – NRC 7 and JS 335. Foliar application of SA showed positive effect on seed yield, seed health, germination and seed vigour during storage. Plant height was significantly improved by the GA3 spray in both the varieties. Significantly higher seed yield was obtained with foliar spray of a-tocopherol. Application of SA was found effective to protect plants from various diseases to get quality seed. a-Tocopherol and K2HPO4 treatment significantly reduced MDA production in seeds. a-Tocopherol application increased super oxide dismutase activity as a result the lipid peroxidation of seed during storage was significantly reduced. Application of a-tocopherol, K2HPO4 and salicylic acid improved the storage or keeping quality of soybean seed.
Standardization of organic module for sustainable production of fenugreek (Trigonella foenum graecum L.)
Authors: Lal1 G. , Singh2 Ravindra , Mehta R.S. , Sharma Y.K. , Kant Krishna , Maheria S.P.
Published: August 2016

A field experiment on the standardization of organic module for production of fenugreek (Trigonella foenum graecum L.) was conducted during rabi season of 2009-10 to 2012-13 (four years). The experiment was laid out in Factorial Randomized Block Design (RBD) consisting of three organic modules (M1, M2 and M3) and two fenugreek varieties (AFg-1 and RMt-305) with four replications. Findings of present study showed significant differences among the performance of different organic modules tested for two fenugreek varieties. Organic module-1 (M1)comprising of soil application of vermi-compost @5 t/ha+ foliar spray of 5% garlic extract @ 2.0 kg/ha + 2% neem oil @ 5 litre/ha+ soil application of neem cake @150 kg/ha and Trichoderma @ 2.5 kg/ha, seed treatment with Rhizobium @100 ml/kg seed, PSB @ 100 ml/kg seed and Trichoderma @10 g/kg seed exhibited earliest seed germination and maximum plant height (5.78, 19.69, 43.39 and 50.97 cm) at 30, 60, 90 DAS and at harvest, respectively with maximum number of branches (6.76/ plant), number of pods (42/ plant), number of seeds (16.01/ pod), highest grain yield (1515.21 kg/ha), gross return (100004) and net returns (66741) in fenugreek crop. Similarly significant differences were recorded in the performance of fenugreek varieties under different organic modules and the highest plant height, maximum number of branches and pods per plant, highest number of seeds per pod with maximum grain yield (1568.36 kg/ha), gross returns (103512), net returns (71399) with higher B:C ratio (2.22) were recorded in fenugreek variety AFg-1 than variety RMt-305. Cultivation of fenugreek variety AFg-1 with the application of Module-1 exhibited maximum values for all the growth parameters, yield attributing characters, maximum grain yield, net returns with improvement in soil organic carbon % (OC) and soil fertility (available N, P and K) after 4 crop cycles. Hence, variety AFg-1 is recommended to grow organically with the application of Module-1 (M1) under semi-arid environmental conditions.
Estilo directo e indirecto en el Corpus sociolingüístico de Caracas 1987
Authors: Gallucci María José , Vargas Kerlys
Published: August 2016

En esta investigación analizamos el uso del estilo directo (ED) y el estilo indirecto (EI), dos de los mecanismos más frecuentes en la oralidad para citar de manera explícita palabras o pensamientos. En esta oportunidad, analizamos una muestra del Corpus sociolingüístico de Caracas 1987 (Bentivoglio y Sedano, 1993) conformada por 12 hablantes estratificados según la variable sexo. Los criterios considerados para el análisis fueron: marco introductor, verbos, atribución de la palabra, funciones pragmáticas de las citas y uso de cada una de estas categorías según el sexo de los hablantes. Los resultados obtenidos muestran que: i) el ED es más empleado que el EI y no existe mayor diferencia entre el uso de uno y otro estilo por parte de hombres y mujeres; ii) la forma de introducción más frecuente se manifiesta a través de un verbo y, en menor proporción, sin él; iii) hay una tendencia por parte de las mujeres a citar empleando como marco introductor un verbo, mientras que los hombres suelen elidirlo en más oportunidades; iv) el verbo decir es el más utilizado tanto por hombres como por mujeres; v) los hablantes prefieren citar el discurso de otros; vi) la función pragmática más frecuente es relatar una anécdota, seguida por ejemplificar una circunstancia.
El predominio de uno en Bogotá, Colombia: ¿estrategia para desfocalizar o para subjetivizar?
Authors: Hurtado Luz Marcela
Published: August 2016

Este artículo analiza los factores semántico-pragmáticos que influyen en el uso del pronombre uno en el habla de Bogotá. Mediante un enfoque variacionista y con base en los resultados del programa estadístico Goldvarb, se advierte una reducción de la característica impersonal de uno, pues se utiliza principalmente como marcador de la postura del hablante (subjetivización del discurso) más que como mecanismo para disminuir su protagonismo. Los resultados de las variables de clase semántica del verbo, tipo de discurso y clase de entrevista aportan evidencia acerca de la utilización de uno casi con las mismas funciones referenciales de yo con verbos emotivos, mentales y estativos, en narraciones y situaciones hipotéticas, y en interacciones informales y espontáneas. Estos resultados apuntan a la pérdida de la antigua connotación socio-pragmática de un sobreuso característico de los individuos con menor nivel económico y educativo.