bluuebunny/crossref_metadata_2025 huggingface dataset:
A comprehensive study of the velocity, momentum and position matrix elements for Bloch states: Application to a local orbital basis
Authors: Esteve-Paredes Juan José , Palacios Juan José
Published: January 2023

We present a comprehensive study of the velocity operator,
\hat{\boldsymbol{v}}=\frac{i}{\hbar} [\hat{H},\hat{\boldsymbol{r}}]\,𝐯̂=iℏ[Ĥ,𝐫̂],
when used in crystalline solids calculations. The velocity operator is
key to the evaluation of a number of physical properties and its
computation, both from a practical and fundamental perspective, has been
a long-standing debate for decades. Our work summarizes the different
approaches found in the literature, but never connected before in a
comprehensive manner. In particular we show how one can compute the
velocity matrix elements following two different routes. One where the
commutator is explicitly used and another one where the commutator is
avoided by relying on the Berry connection. We work out an expression in
the latter scheme to compute velocity matrix elements, generalizing
previous results. In addition, we show how this procedure avoids
ambiguous mathematical steps and how to properly deal with the two
popular gauge choices that coexist in the literature. As an illustration
of all this, we present several examples using tight-binding models and
local density functional theory calculations, in particular using
Gaussian-type localized orbitals as basis sets. We show how the the
velocity operator cannot be approximated, in general, by the k-gradient
of the Bloch Hamiltonian matrix when a non-orthonormal basis set is
used. Finally, we also compare with its real-space evaluation through
the identification with the canonical momentum operator when possible.
This comparison offers us, in addition, a glimpse of the importance of
non-local corrections, which may invalidate the naive momentum-velocity
correspondence.
Spicy plants in the landscape compositions of the Syrets Arboretum
Authors: Mykhailyk S. M. , Glukhova S. A. , Shynder O. I.
Published: January 2023

Purpose. To analyze the taxonomic and varietal diversity of the collection of spicy plants of the Syrets Arboretum, evaluate their decorative qualities and determine the directions of use in landscape design. Methods. The subject of the study is spicy plants grown on the territory of the Syrets Arboretum, which are a part of the collection of open ground plants. The species and varieties of this group of plants were introduced in the arboretum from 1949 to 2021. In the process of research, methods of analysis and synthesis, comparison and generalization of information were used. Results. It has been established that the collection of spicy plants of the Syrets Arboretum includes 69 taxa belonging to 33 gene­ra, 12 families.  There are 52 species and 25 cultivars among them. The largest number of representatives are in the families Lamiaˆceae – 32 taxa, Amaryllidaceae – 11 taxa and Aste­raceae – 9 taxa. The life forms of spicy plants are represented by woody (19 taxa) and herbal plants (50 taxa, of which 10 annual, 2 biennial, and 38 perennial forms). The traditional fields of application of spicy plants are food, medicine (pharmacology) and perfumery. In addition, their decorative varieties and cultivars are used to create landscape compositions. In particular, on the territory of the Syrets Arboretum, spicy plants are the compositional basis of the thematic “garden of spicy aromatic plants”, they are used as elements of classic flower beds and summer compositions, thematic compositions (national and pharmacy gardens, vegetable flower beds), alpine slides and rocky gardens, etc. Conclusions. Many years of experience in landscape design and creation of floral arrangements in the Syrets Arboretum showes that spicy plants are an important element in all types of tested decorative compositions. It is revealed that out of 69 spicy plants that grow on collectible plantings of the Sirets Arboretum, 51 have decorative qualities and are used as decorative-floral and decorative-deciduous species. The taxonomic and varietal variety of spicy plants has considerable potential for breeding work and creation of highly decorative landscape compositions of various purposes. Due to the availability of different life forms and biomorphological features, it is advi­sable to use spicy plants in different types of plantations for decorative gardening and landscape design.
Evaluation of winter wheat varieties and promising lines of Myronovka’s intitute breeding in terms of grain quality
Authors: Topko R. I. , Kovalyshyna H. M.
Published: January 2023

Purpose. To evaluate the varieties: ‘MIP Assol’, ‘Balada Myronivska’, ‘Hratsiia Myronivska’, ‘MIP Yuvileina’, ‘MIP Lada’, ‘MIP Dniprianka’ and the standard variety ‘Podolianka’ and promising breeding lines: ‘Erythrospermum 55023’, ‘Lutescens 22198’, ‘Lutescens 37519’, ‘Lutescens 60049’, ‘Lutescens 60107’ winter wheat of the Mironovka`s breeding according to grain quality indicators.
Methods. The research was conducted during the 2019–2021 in the breeding crop rotation of the winter wheat breeding laboratory of the V. M. Remeslo Myronivka Institute of Wheat, NAАS of Ukraine. The main method of research was laboratory and field, supplemented by analytical studies, measurements, calculations and observations.
Results. The following breeding lines were the best in terms of protein content during the first sowing period: ‘Erythrospermum 55023’ (11.9%), ‘Lutescens 55198’ (12.8%), ‘Lutescens 37519’ (11.7%) and ‘Lutescens 60107’ (10.7%). During the second sowing period, the best varieties and breeding lines turned out to be ‘Hratsiia Myronivska’ (11.4%), ‘MIP Dniprianka’ (12.3%), ‘Erythrospermum 55023’ (12.3 %), ‘Lutescens 55198’ (11.4%), ‘Lutescens 37519’ (12.3%) and ‘Lutescens 60049’ (12.8%). According to the grain vitrification index during the first sowing period, the following can be distinguished: ‘Balada Myronivska’ (86.7%), ‘MIP Lada’ (89.3%), ‘MIP Dniprianka’ (87.3%), ‘Erythrospermum 55023’ (86.3 %), ‘Lutescens 55198’ (94.3 %) and ‘Lutescens 37519’ (91.0 %). During the second sowing period, these were ‘Balada Myronivska’ (86.7%), ‘Hratsiia Myronivska’ (79.3%), ‘MIP Lada’ (85.0%), ‘MIP Dniprianka’ (81.7%) and breeding lines ‘Lutescens 55198’ (80.7%) and ‘Lutescens 60049’ (81.3%). According to the content of raw gluten, the variety ‘Hratsiia Myronivska’ (26.2%) was selected. For all studied breeding lines, the value of the crude gluten content indicator varied from 26.0% to 29.9%. Du­ring the second sowing period, a higher percentage of raw gluten content was noted in the varieties ‘Hratsiia Myronivska’ (29.9%) and ‘MIP Dniprianka’ (27.4%) and selection lines – ‘Erythrospermum 55023’ (28.4%), ‘Lutescens 55198’ (27.4%), ‘Lutescens 37519’ (27.1%) and ‘Lutescens 60049’ (29.1%).
Conclusions. During the three years of observations, the weather conditions differed in the amount of precipitation and the sum of active temperatures both during the growing season and during the period of flowering and maturation, which significantly affected the results of the analysis of grain quality indicators of winter wheat varieties and promising lines. Having analyzed the obtained results, it is possible to single out the varieties ‘Hratsiia Myronivska’ and ‘MIP Dniprianka’, as well as the breeding lines: ‘Erythrospermum 55023’, ‘Lutescens 55198’, ‘Lutescens 37519’ and ‘Lutescens 60049’, which exceeded the standard variety ‘Podolianka’ and the average experimental values for such basic indicators as protein content, gluten content, vitreousness and 1000-seed weight.
The influence of moistening conditions and seed treatment with biological preparations on the growth and yield of winter wheat varieties
Authors: Korkhova M. M. , Markova N. V. , Panfilova A. V.
Published: January 2023

Purpose. To determine the influence of the moistening conditions and treatment of seeds with biological preparations Azotofit-r, Fitotsyd, Mycofriend-r, Orhanik-balans Monofosfor on growth processes at the initial plant life stages, formation of stand density and grain yield of winter wheat varieties. Methods. General scientific, special, field, mathematical-statistical and calculation-comparative methods were used for research. Results. The key to a high yield of winter wheat is in obtaining even stands, forming the optimal density of plant stands at the time of harvesting, taking into account their survival rates, the coefficient of productive tillering, and the study of new varieties adapted to climate changes. According to the research results, it was determined that, on average, for 2020–2022, the highest grain yield among the studied varieties of winter wheat was recorded in plants of the variety ‘Duma Odeska’ (8.38 t/ha) under irrigation in the variant with pre-sowing treatment of seeds with the biopreparation Azotofit-r, which was 0.78 t/ha more compared to the control (treatment with water). In the variant without irrigation, the yield was 6.08 t/ha, which was less than the control by 2.3 t/ha or 27.4%. Conclusions. The developed elements of the technology of winter wheat varieties growing make it possible to form the optimal plant density and significantly increase grain yield in the conditions of the Southern Steppe of Ukraine
Historical aspects of the formation of national plant varietal resources in Ukraine
Authors: Leschuk N. V. , Melnyk S. I. , Marchenko T. M. , Kokhovska I. V. , Sytnyk V. G.
Published: January 2023

Introduction. National varietal plant resources are of particular importance for the economic development of Ukraine, because they ensure the stability of the crop industry as a component of the country’s food security. The analysis of the historiography of the development of the state variety testing since 1923 showed the lack of a systematic study of the formation of the State Register of Plant Varieties suitable for distribution in Ukraine (hereinafter – the Register of Plant Varieties of Ukraine). Purpose. To reveal the historical stages of the formation of national plant varietal resources, and substantiate the concept of their development. Methods. A collection of commonly known plant varieties that are or were in commercial circulation. Research methods – general scientific: hypothesis, observation, analysis, synthesis method for drawing conclusions; source study database with elements of extrapolation, which is formed based on the results of field, laboratory and analytical research. Results. The study of the history of state variety testing regulation made it possible to find out that the variety testing netork in Ukraine was established in 1923. The refore, the formation of national varietal plant resources has its own almost a hundred-year history. At all historical stages of the formation of national varietal resources, a variety with a complex of its morphobiological and economically valuable characteristics remains the subject of the research. State registration of a variety or rights to it ensures the commercial circulation of the variety. Identification of plant varieties, as the basis for varietal certification, increases the turnover of varieties on the market, ensures the growth of production volumes and improves the quality of crop products. Plant varieties distributed on the territory of Ukraine correspond to the criteria of distinctness, uniformity and stability generally accepted in international practice; meet the needs of consumers in terms of economically valuable characteristics; do not threaten the environment and human health. The formation of national plant varietal resources takes place in stages with the tendency to increase the economically valuable criteria, which ensures the competitiveness of the modern market of varieties and seeds in accordance with international requirements. Conclusions. The formation of plant varietal resources to meet the needs of consumers and/or breeding practice in Ukraine took place due to rather long historical stages of development and introduction of plant diversity, forms, criteria and methodology of varietal testing in time and space. The substantiation of the historical aspects of the concept of the varietal resources formation will allow optimizing the structure of the variety testing network, organizational foundations of the state registration of varieties and the protection of breeder’s rights.
INVESTIGAÇÃO DA ATIVIDADE ELETROQUÍMICA DE LIGA Al-Cu-Li APÓS PROCESSO DE SOLDAGEM POR FRICÇÃO E MISTURA
Authors: da Silva Rejane , Milagre Mariana , Araujo João Victor , Ramirez Oscar , Machado Caruline , Antunes Renato , Costa Isolda
Published: January 2023

INVESTIGATION OF THE ELECTROCHEMICAL ACTIVITY OF AN Al-Cu-Li ALLOY AFTER FRICTION STIR WELDING PROCESS. In this work, the local electrochemical activity of the zones coupled by Friction Stir Welding (FSW) of an Al-Cu-Li alloy was studied and the results were correlated to the microstructural characteristics of each zone. Electrochemical studies were carried out in the zones affected by welding using cyclic voltammetry (CV) and scanning electrochemical techniques (namely, SECM - Scanning Electrochemical Microscopy and LEIS – Local electrochemical impedance spectroscopy). The results showed that the welding joint (WJ) is predominantly cathodic relatively to the heat affected zones (HAZ). The HAZ was always anodic and showed the highest electrochemical activities among the tested ones. The high electrochemical activity of the HAZ was associated with the effect of galvanic coupling between the cathodic region (WJ) and the anodic region (HAZ). In addition, the advancing side (AS) presented increased electrochemical activity compared to the retreating one (RS).
Silver Tungstate Obtained via Successive Seed Crystal Growth: Structural, Morphological, Optical, and Photocatalytic Properties
Authors: Santos Germano , Silva Francisco , Cruz-Filho João , Luza Roberto , Luz Jr. Geraldo
Published: January 2023

Synthesis routes and parameters such as synthesis time, precursor molar ratio, pH, and temperature are critical for generating oxides of various sizes and morphological aspects. However, there is no information on how to prepare silver tungstate (Ag2WO4) crystals of different shapes and sizes under laboratory conditions and without using sulfating agents. In this study, we attempted to fill this gap by preparing α-Ag2WO4 crystals of various sizes and morphologies using the coprecipitation method in a 3 h interval at room temperature and without using sulfating agents. The powder X-ray diffraction analysis confirmed that all crystals had an orthorhombic structure, whereas Fourier-transform infrared spectroscopy revealed the degree of structural disorder in the bonds between the atoms in the materials. Scanning electron microscopy revealed that the α-Ag2WO4 crystals had different sizes (5.37-26.83 μm) and morphologies (tetragonal prism, rod, and cypress leave-like rod), whereas ultraviolet-visible diffuse reflectance spectroscopy analysis indicated the optical band gap energy (2.92-3.05 eV), calculated using the method proposed by Kubelka and Munk. Catalytic tests revealed that the synthesized samples with the smallest crystals (AW1) and a tetragonal prism morphology degraded dye more efficiently (apparent rate constant (k) = 5.86 × 10−3 min−1) than other samples.
Analysis of longitudinal and torsional vibration of mining scraper conveyor under the over bending section working condition
Authors: Xie Chunxue , Liu Zhixiang , Xie Miao
Published: January 2023

Considering that the scraper will produce longitudinal and torsional pendulum vibration when passing through the bending section, and have a great influence on the motion characteristics of the scraper conveyor, this paper studies the longitudinal and torsional pendulum coupling vibration characteristics of the scraper conveyor under the working condition of over-bending section for the first time. Firstly, the simplified model of torsional pendulum vibration of scraper chain system is established based on Voigt model and point-by-point tension method. Then, the change law of scraper group vibration and chain tension under the condition of scraper bending is studied. Thirdly, through the influence area and attenuation characteristics of torsional pendulum vibration, the thumbnail model of torsional pendulum vibration is constructed. Finally, the longitudinal and torsional pendulum coupling vibration dynamic model of the scraper chain system is constructed based on the torsional pendulum vibration abbreviation model, and the overall longitudinal and torsional pendulum vibration characteristics of the scraper conveyor are studied when the scraper is over the bending section. The conclusion of this paper provides a theoretical basis for better understanding the operation characteristics of scraper conveyor in coal mine.
Measures aimed at supporting families during the COVID-19 pandemic in Italy
Authors:   University of Modena and Reggio Emilia, Marco Biagi Foundation, Rymkevich Olga
Published: January 2023

This article provides an overview of the main measures adopted by the Italian government to support families during the COVID-19 pandemic. The package of measures included the extension of possibilities to take paid or unpaid parental leave, monetary allowances, and incentives to use remote work. These measures are aimed at ensuring safe working conditions and curbing the spread of the virus, supporting family incomes, as well as maintaining overall economic stability, and avoiding mass layoffs and interruptions in the provision of basic services. Thus, extraordinary parental leave is granted to a wider range of people than “standard” leave, and it provides a higher amount of payments with protection during the leave period from dismissals and with the preservation of the workplace. In cases where the use of leave is not possible, as an alternative measure, funds are provided to pay for child care, and they can be paid during the period of annual paid leave, maternity leave, and parental leave, but they are not provided for remote work and suspension from work. One of their most popular tools is the transfer to remote work, which allows you to ensure the continuity of work in a safe environment and guarantee the combination of work with personal life. All these measures make it possible to compensate for the lack of public and private educational and childcare services, as well as to provide economic support to parents.
Should we reveal everything to the employer? The problem of age disclosure during the recruitment process
Authors:   University of Lodz, Sypecki Piotr
Published: January 2023

Recruitment is a process that usually leads to an employment relationship. It is the phase during which the potential employee and employer gather information that will determine the establishment of a contract. щe party interested in presenting him/herself in the best possible way is usually the applicant, who wants to obtain the desired employment. To achieve this, he or she diligently prepares documents that include information required by the employer. Over the last few years, the scope of this required information has changed considerably — there has been a gradual move away from providing data typically regarded as unnecessary for the recruitment process, and an objective approach has been adopted instead. Currently, fnding data like criminal records, marital status, or even a candidate’s image in application documents is uncommon. Sometimes employers recommend limiting the scope of information and even implement anonymizing processes in which applicants indicate their experience and skills only. щe reason for this can be attributed to the development of anti-discrimination and data protection legislation, and the willingness of employers to comply with these laws. Considering the above, all practices and regulations that allow the processing of data unnecessary for the recruitment process should be viewed critically. An example of such legislation is the Polish Labor Code, which allows for the date of birth (age) of every applicant to be obtained. This essay critically analyzes this regulation through several supporting arguments.
VISIBILIDADE PORNOGRÁFICA E CONSUMO
Authors: Moreira da Silva Allyson Darlan , Do Nascimento Kelvis Leandro
Published: January 2023

Neste artigo nos propomos investigar as dinâmicas de interação, consumo e práticas sexuais realizadas no site de webcam denominado Câmera Privê, dissertando sobre o modelo de produção da indústria pornográfica na atualidade e as transformações que a mediação da vida social pelos dispositivos digitais de comunicação tem gerado no campo da sexualidade humana. No atual regime de hipervisibilidade, partindo da ideia de sociedade pornográfica em Byung-Chul Han (2017), discorremos sobre como o narcisismo é potencializado pelo acesso crescente a web, tornando as sujeitos mais suscetíveis à vigilância, hiperconsumo, controle e perda da identidade e singularidade subjetiva.
MUDANÇAS CLIMÁTICAS, EXPERIMENTAÇÃO DE POLÍTICAS PÚBLICAS E CAPACIDADE ADAPTATIVA NA CIDADE DE CURITIBA/PR-BRASIL
Authors: Pontes Teixeira Rylanneive Leonardo , Pessoa Zoraide Souza
Published: January 2023

As mudanças climáticas configuram-se em um fenômeno global, mas com efeitos, sobretudo, locais. Então, compreender o que os governos locais têm feito para efetivar suas capacidades de adaptação a tais efeitos é um importante passo na construção de cidades menos vulneráveis e mais sustentáveis. Neste sentido, o objetivo deste artigo é analisar como a cidade de Curitiba/PR tem internalizado a questão climática, analisando as experimentações e os desafios que se têm enfrentado para responder aos efeitos das mudanças climáticas que acometem sua população. Para isso, a metodologia segue uma abordagem de natureza qualitativa, fazendo uso de métodos de pesquisa como análise documental, aplicação de entrevistas e análise de conteúdo. A partir da análise dos documentos e das entrevistas, os resultados deste trabalho permitem concluir que, embora Curitiba possua experimentações de políticas públicas direcionadas às mudanças climáticas, apresenta ainda uma série de desafios para efetivar sua capacidade de gestão urbana na qual tenha a adaptação climática como estratégia.
JUVENTUDE E MUDANÇAS CLIMÁTICAS
Authors: Silva Júnior Marcos Aurélio Freire da , Pontes Teixeira Rylanneive Leonardo
Published: January 2023

O tema da juventude se cruza com a questão ambiental quando, no contexto contemporâneo, tem aumentado a atuação dos jovens frente às mudanças climáticas. Nesse sentido, o objetivo deste artigo é compreender e analisar, através das narrativas, as trajetórias dos jovens e as estratégias dos movimentos ativistas brasileiros que se mobilizam em torno das mudanças climáticas. Para tanto, a metodologia da pesquisa é qualitativa, fazendo uso do levantamento bibliográfico e da aplicação de entrevistas semiestruturadas. A técnica de análise dos dados é a análise de conteúdo. A partir dos resultados obtidos, concluímos que as trajetórias dos jovens estão ancoradas na influência familiar e na inserção no movimento estudantil. Ademais, as estratégias utilizadas se ancoram, principalmente, na conjuntura política ou no diálogo com o poder público.

Palavras-chave: Jovens. Movimentos sociais. Questão ambiental. Crise climática.
Вводный обзор теорий построения зрительного образа
Authors: Вороная Виктория Д.
Published: January 2023

Зрительное восприятие, по-прежнему являясь актуальной проблемой, рассматриваемой с углов механизмов перцепции, детекции признаков, практического применения в исследованиях и прочих, в данной работе рассматривается с теоретической точки зрения, а именно с позиции подходов авторов-исследователей к его организации и построению видимого зрительного образа. Так, целью данного исследования выступает обобщение и анализ некоторых базовых теорий построения зрительного образа в доступной форме, что и отражает новизну исследования. Приведение в статье ориентационных знаний, необходимых для анализа пласта накопленных теоретических и практических материалов, связанных с проблемами построения зрительного образа, позволяет осваивать научные материалы, посвящённые теориям Дж. Гибсона, Д. Марра и иных упомянутых авторов. В теоретическом обосновании приведены базовые знания о составе и отличительных особенностях теорий. Так, отмечается субъективность восприятия и активность субъекта в экологическом подходе Гибсона. Отмечена идея формирования внутренних репрезентаций и моделирования процессов восприятия в концепции Д. Марра. Рассмотрена одна из базовых теорий иерерхической организации зрительной коры, предложенная Д. Хьюбелом и Т. Визелем. Многостадийность зрительного восприятия отмечена в подразделе, посвященном теории интеграции признаков А. Трейсман. В том числе в русле когнитивной психологии обозначены особенности и этапы перцептивного цикла по У. Найссеру. В обсуждении результатов отмечены ограничения данного теоретического обзора, а также проведен анализ существующих отражений теорий в научных трудах и будущих перспектив их построения авторами.
Long Noncoding RNA and mRNA Expression Profiles in Rats with LPSinduced
Myocardial Dysfunction
Authors: Xie Hong-Zhi , Han Ye-Chen , Shen Zhu-Jun , Xiang Ruo-Lan , Lu Bo , Qian Hao , Li Jing-Yi
Published: January 2023

Background:

Sepsis is an uncontrolled systemic inflammatory response. Long noncoding
RNAs (lncRNAs) are involved in the pathogenesis of sepsis. However, little is known about the roles
of lncRNAs in sepsis-induced myocardial dysfunction.

Objective:

We aimed to determine the regulatory mechanism of lncRNAs in sepsis-induced myocardial
dysfunction.

Methods:

In this study, we analysed the lncRNA and mRNA expression profiles using microarray
analysis. Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, protein-protein interaction
network, and gene set enrichment analysis were used to evaluate the data. We also constructed coding
and noncoding coexpression and competing endogenous RNA networks to investigate the mechanisms.

Results:

In vivo lipopolysaccharide -induced sepsis rat model was established. A total of 387 lncRNAs
and 1,952 mRNAs were identified as significantly changed in the left ventricle. Kyoto Encyclopedia
of Genes and Genomes analysis of mRNAs showed that the upregulated genes were mainly enriched
in the “complement and coagulation cascade pathway” and “immune-related biological processes”
terms. Eight significantly changed lncRNAs detected by RT-qPCR may be responsible for these processes.
A competing endogenous RNA network was generated, and the results indicated that eight
lncRNAs were related to the “calcium ion binding” process.

Conclusion:

These results demonstrate that crosstalk between lncRNAs and mRNAs may play important
roles in the development of sepsis-induced myocardial dysfunction.
Whole Exome Sequencing Identified Two Single Nucleotide Polymorphisms
of Human Leukocyte Antigen-DRB5 in Familial Sarcoidosis in
China
Authors: Zhang Qian , Xu Zuojun , Huang Hui , Zhang Meijun
Published: January 2023

Background:

Sarcoidosis is a multisystem granulomatous disorder whose etiology is related
to genetic and immunological factors. Familial aggregation and ethnic prevalence suggest a genetic
predisposition and inherited susceptibility to sarcoidosis.

Objective:

This study aimed to identify suspected risk loci for familial sarcoidosis patients.

Methods:

We conducted whole exome sequencing on two sarcoidosis patients and five healthy family
members in a Chinese family for a case-control study. The two sarcoidosis patients were siblings who
showed chronic disease.

Results:

The Gene Ontology results showed single nucleotide polymorphisms in three genes, including
human leukocyte antigen (HLA)-DRB1, HLA-DRB5, and KIR2DL4, associated with both ‘antigen
processing and presentation’ and ‘regulation of immune response.’ Sanger sequencing verified two
nonsynonymous mutations in HLA-DRB5 (rs696318 and rs115817940) located on 6p21.3 in the major
histocompatibility complex (MHC) class II beta 1 region. The structural model simulated on Prot-
Param protein analysis by the Expert Protein Analysis System predicted that the hydropathy index
changed at two mutation sites (rs696318: p.F96L, -1.844 to -1.656 and rs115817940: p.T106N, -0.322
to -0.633), which indicated the probability of changes in peptide-binding selectivity.

Conclusion:

Our results indicated that two nonsynonymous mutations of HLA-DRB5 have been identified
in two sarcoidosis siblings, while their healthy family members do not have the mutations. The
two HLA-DRB5 alleles may influence genetic susceptibility and chronic disease progression through
peptide mutations on the MHC class II molecule among the two affected family members.
Coronary Microvascular Dysfunction in Patients with Congenital Heart
Disease
Authors: Vanreusel Inne , Segers Vincent F.M. , Craenenbroeck Emeline Van , Berendoncks An Van
Published: January 2023

Congenital heart diseases represent a wide range of cardiac malformations. Medical and surgical advances have dramatically increased the survival of patients with congenital heart disease, leading to a continuously growing number of children, adolescents, and adults with congenital heart disease. Nevertheless, congenital heart disease patients have a worse prognosis compared to healthy individuals of similar age. There is substantial overlap in the pathophysiology of congenital heart disease and heart failure induced by other etiologies. Among the pathophysiological changes in heart failure, coronary microvascular dysfunction has recently emerged as a crucial modulator of disease initiation and progression. Similarly, coronary microvascular dysfunction could be important in the pathophysiology of congenital heart diseases as well.
For this systematic review, studies on maximal vasodilatory capacity in the coronary microvascular bed in patients with congenital heart disease were searched using the PubMed database.
To date, coronary microvascular dysfunction in congenital heart disease patients is incompletely understood because studies on this topic are rare and heterogeneous. The prevalence, extent, and pathophysiological relevance of coronary microvascular dysfunction in congenital heart diseases remain to be elucidated. Herein, we discuss what is currently known about coronary microvascular dysfunction in congenital heart disease and future directions.

Congenital heart diseases represent a wide range of cardiac malformations. Medical and
surgical advances have dramatically increased the survival of patients with congenital heart disease,
leading to a continuously growing number of children, adolescents, and adults with congenital
heart disease. Nevertheless, congenital heart disease patients have a worse prognosis compared
to healthy individuals of similar age. There is substantial overlap in the pathophysiology of congenital
heart disease and heart failure induced by other etiologies. Among the pathophysiological
changes in heart failure, coronary microvascular dysfunction has recently emerged as a crucial
modulator of disease initiation and progression. Similarly, coronary microvascular dysfunction
could be important in the pathophysiology of congenital heart diseases as well.
For this systematic review, studies on maximal vasodilatory capacity in the coronary microvascular
bed in patients with congenital heart disease were searched using the PubMed database.
To date, coronary microvascular dysfunction in congenital heart disease patients is incompletely
understood because studies on this topic are rare and heterogeneous. The prevalence, extent, and
pathophysiological relevance of coronary microvascular dysfunction in congenital heart diseases
remain to be elucidated. Herein, we discuss what is currently known about coronary microvascular
dysfunction in congenital heart disease and future directions.
The Relationship between Emotional Reactions and Coping Strategies of Nurses during the Outbreak of COVID-19 in Ganjavian Hospital in Dezful in 2020
Authors: Sarabi Nasrin , Masoudiyekta Leila , Pour Fatemeh Jafari , Mahnaz Nosratabadi , Mirsamiyazdi Nastaran , fathi Saba , Hamidipour Nasim
Published: January 2023

Background:

Nurses face challenges when they are in a stressful situation and therefore use strategies to adapt.

Objective:

Considering the importance of the type of strategy used by nurses to maintain their mental health and considering the differences in the results of studies on the applicability of coping strategies, the present study investigates the emotional reactions and coping strategies of nurses during the COVID-19 pandemic.

Methods:

The present study is a cross-sectional (descriptive-analytical) study involving 208 nurses working in Ganjavian Hospital in Dezful in 2020. The instruments used in the questionnaire are: emotional reactions, demographic and coping style questionnaire preference for modified coping practices.

Results:

The results showed that the mean age of nurses participating in the study was 31.15±7.25 years. Most emotional reactions were related to nurses' feelings of desire with an average of 3.44 ±1. 23 and the lowest related to disgust with a mean of 2.44 ±1.26. The highest coping actions of nurses were related to nurses' emotional coping strategy with a mean of 26.87 ± 4.5. There was a significant relationship between problem-solving coping strategies with emotional disgust and direct anxiety.

Conclusion:

Due to the high level of hope and anxiety in nurses and the adoption of coping strategies focused on emotion, hospital managers and mental health managers should focus on providing psychological support to nurses and teaching problem-oriented coping strategies. They should also encourage the nurses to deal with their high level of hope for the high anxiety caused by Covid disease.
A Review of Crash Modification Factor (CMF) Estimation
Authors: Al-Marafi Mohammad Nour , Somasundaraswaran Kathirgamalingam
Published: January 2023

Background

Road authorities and road safety experts are involved with estimating the expected outcomes originating from road safety treatments. Information derived from proposed treatments enables planners to make comparisons between the expected savings from crash reductions and associated treatment costs.

Aim

The purpose of this review is to provide direction to agencies and practitioners interested in estimating safety effectiveness.

Methods

Specifically, this study discusses the main methods for developing CMFs, including an overview of each method, data considerations, and their strengths and weaknesses. It also discusses the techniques of estimating combined CMFs resulting from multiple safety treatments.

Results

The review showed that observational Before–After (BA) studies with the Empirical Bayes (EB) and Full Bayes (FB) approaches provides enhanced consistency and precision for the estimated safety effectiveness. Alternatively, the cross-sectional method can be adopted in cases where observational BA studies are not practical due to data restrictions. Five additional techniques for estimating combined CMFs are also reviewed.

Conclusion

The study notes that while there has been substantial research in the broad area, very few studies have reported comparative methods of combined CMF estimation. Future research directions and research gaps are also highlighted in this review.
Behavioral, Sociodemographic, and Sleep Correlates of Symptoms of Depression amongst Older Brazilian Females According to Age: A Cross- Sectional Network Analysis
Authors: Bohn Lucimere , Abdalla Pedro Pugliesi , Chen Sitong , de Queiroz Neto Elzier Sampaio , Lopes Machado Dalmo Roberto , Mota Jorge , Martins Lucena Clarice
Published: January 2023

Background:

Examining the interrelationships between symptoms of depression and sociodemographic and behavioral correlates is challengeful using traditional regression analysis.

Objective:

to identify the sociodemographic, movement behaviors, and sleep correlates that contribute the most to symptoms of depression in Brazilian older females, using a network analysis approach.

Methods:

This cross-sectional study analyzed 1019 older females from Brazil. Data (sociodemographic, height (meters), weight (kilograms), symptoms of depression, physical activity, sleep) were self-reported via phone calls. The relationships between symptoms of depression and their correlates were assessed using the Network Analysis (qgraph package of the Rstudio) for entire sample and age groups (60-69; 70-79 and 80+ years old).

Results:

60-69 and 70-79 groups have more weekly home exits, with aging “single, widowed or divorced” was progressively higher, and “married or stable union” and Overweight/obesity were progressively fewer (p < 0.05). 60-69 have more education years and fewest medicaments use. Sleep compliance (for the entire sample), body mass index (for the 60-69), compliance with moderate to vigorous physical activity (for the 70-79), and educational level (for 80+) were the variables with the highest expected influence values (p < 0.05) on symptoms of depression (1.370; 1.388; 1.129; and 1.354, respectively).

Conclusion:

Symptoms of depression vary throughout the aging process and thus determine that intervention strategies encompass these specific factors according to each age group. Poor sleep behavior has a strong positive association with symptoms of depression. This result highlights that health professionals must be aware of the importance of sleep to mitigate the worsening of depression among older Brazilian females.
Ionic Liquids as Inhibitors of Hydrate Formation in Deepwater Wells
Authors: Martínez Palou Rafael , Likhanova Natalya V.
Published: January 2023

The extraction of crude oil in deep waters represents a major technological
challenge. One of the most common problems in these oil and gas extraction conditions
is the formation of gas hydrates that can cause plugging and hinder the transportation
of crude oil. For this reason, great efforts have been made in the development of
hydrate inhibitors, among which ILs have shown to be a very promising alternative. In
this chapter, the development and evaluation of ILs as hydrate inhibitors are discussed. 
The effectiveness of pranic complementary therapy to reduce post COVID-19 anxiety in elderly
Authors: Diniari Ni Ketut Sri , Ayu Ketut , Widiana Gede Raka
Published: January 2023

Background. COVID-19 affects all aspects of life globally including the elderly who are a vulnerable population experiencing psychosocial disorders. They are vulnerable to mental disorders during the pandemic such as stress, anxiety, depression, post-traumatic stress disorder, suicide, and aggravation of pre-existing mental disorders. The choice of anxiety therapy in the elderly is prioritized to be non-pharmacological therapy to avoid polypharmacy and the side effects of pharmacological therapy. Pranic healing therapy is a complementary therapy that can be a therapeutic option used to reduce anxiety in the elderly after suffering from COVID-19. Methods. This research is an experimental study with a randomized controlled trial design. Furthermore, 20 elderly patients with post-COVID-19 anxiety who received pharmacological therapy and Cognitive Behavioral Therapy with pranic therapy intervention were compared with the control 20 elderly patients post-COVID-19 with pharmacological therapy and Cognitive Behavioral Therapy without Prana therapy. Results. The characteristics of patients were > 66 years old, mostly male, married, accompanied by comorbid diseases, treated in non-intensive rooms, and experiencing moderate-severe anxiety before getting Prana complementary therapy.
Reaching Populations at Risk for HIV Through Targeted Facebook Advertisements: Cost-Consequence Analysis
Authors: Hanna John J , Saleh Sameh N , Lehmann Christoph U , Nijhawan Ank E , Medford Richard J
Published: January 2023

Background

An undiagnosed HIV infection remains a public health challenge. In the digital era, social media and digital health communication have been widely used to accelerate research, improve consumer health, and facilitate public health interventions including HIV prevention.

Objective

We aimed to evaluate and compare the projected cost and efficacy of different simulated Facebook (FB) advertisement (ad) approaches targeting at-risk populations for HIV based on new HIV diagnosis rates by age group and geographic region in the United States.

Methods

We used the FB ad platform to simulate (without actually launching) an automatically placed video ad for a 10-day duration targeting at-risk populations for HIV. We compared the estimated total ad audience, daily reach, daily clicks, and cost. We tested ads for the age group of 13 to 24 years (in which undiagnosed HIV is most prevalent), other age groups, US geographic regions and states, and different campaign budgets. We then estimated the ad cost per new HIV diagnosis based on HIV positivity rates and the average health care industry conversion rate.

Results

On April 20, 2021, the potential reach of targeted ads to at-risk populations for HIV in the United States was approximately 16 million for all age groups and 3.3 million for age group 13 to 24 years, with the highest potential reach in California, Texas, Florida, and New York. When using different FB ad budgets, the daily reach and daily clicks per US dollar followed a cumulative distribution curve of an exponential function. Using multiple US $10 ten-day ads, the cost per every new HIV diagnosis ranged from US $13.09 to US $37.82, with an average cost of US $19.45. In contrast, a 1-time national ad had a cost of US $72.76 to US $452.25 per new HIV diagnosis (mean US $166.79). The estimated cost per new HIV diagnosis ranged from US $13.96 to US $55.10 for all age groups (highest potential reach and lowest cost in the age groups 20-29 and 30-39 years) and from US $12.55 to US $24.67 for all US regions (with the highest potential reach of 6.2 million and the lowest cost per new HIV diagnosis at US $12.55 in the US South).

Conclusions

Targeted personalized FB ads are a potential means to encourage at-risk populations for HIV to be tested, especially those aged 20 to 39 years in the US South, where the disease burden and potential reach on FB are high and the ad cost per new HIV diagnosis is low. Considering the cost efficiency of ads, the combined cost of multiple low-cost ads may be more economical than a single high-cost ad, suggesting that local FB ads could be more cost-effective than a single large-budget national FB ad.
Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial
Authors: Trinquart Ludovic , Liu Chunyu , McManus David D , Nowak Christopher , Lin Honghuang , Spartano Nicole L , Borrelli Belinda , Benjamin Emelia J , Murabito Joanne M
Published: January 2023

Background

Smartphone apps and mobile health devices offer innovative ways to collect longitudinal cardiovascular data. Randomized evidence regarding effective strategies to maintain longitudinal engagement is limited.

Objective

This study aimed to evaluate smartphone messaging interventions on remote transmission of blood pressure (BP) and heart rate (HR) data.

Methods

We conducted a 2 × 2 × 2 factorial blinded randomized trial with randomization implemented centrally to ensure allocation concealment. We invited participants from the Electronic Framingham Heart Study (eFHS), an e-cohort embedded in the FHS, and asked participants to measure their BP (Withings digital cuff) weekly and wear their smartwatch daily. We assessed 3 weekly notification strategies to promote adherence: personalized versus standard; weekend versus weekday; and morning versus evening. Personalized notifications included the participant’s name and were tailored to whether or not data from the prior week were transmitted to the research team. Intervention notification messages were delivered weekly automatically via the eFHS app. We assessed if participants transmitted at least one BP or HR measurement within 7 days of each notification after randomization. Outcomes were adherence to BP and HR transmission at 3 months (primary) and 6 months (secondary).

Results

Of the 791 FHS participants, 655 (82.8%) were eligible and randomized (mean age 53, SD 9 years; 392/655, 59.8% women; 596/655, 91% White). For the personalized versus standard notifications, 38.9% (126/324) versus 28.8% (94/327) participants sent BP data at 3 months (difference=10.1%, 95% CI 2.9%-17.4%; P=.006), but no significant differences were observed for HR data transmission (212/324, 65.4% vs 209/327, 63.9%; P=.69). Personalized notifications were associated with increased BP and HR data transmission versus standard at 6 months (BP: 107/291, 36.8% vs 66/295, 22.4%; difference=14.4%, 95% CI 7.1- 21.7%; P<.001; HR: 186/281, 66.2% vs 158/281, 56.2%; difference=10%, 95% CI 2%-18%; P=.02). For BP and HR primary or secondary outcomes, there was no evidence of differences in data transmission for notifications sent on weekend versus weekday or morning versus evening.

Conclusions

Personalized notifications increased longitudinal adherence to BP and HR transmission from mobile and digital devices among eFHS participants. Our results suggest that personalized messaging is a powerful tool to promote adherence to mobile health systems in cardiovascular research.

Trial Registration

ClinicalTrials.gov NCT03516019; https://clinicaltrials.gov/ct2/show/NCT03516019
Vet Care Application
Authors: Jiwane Nayan , Waghaye Nimesh , Tahir Mohammad
Published: January 2023

Abstract: As technology advances, a rule-based expert system allows the end-user to enable new types of healthcare systems. The availability of Android OS-based smart phones with more user-friendly GUIs and lower prices, in particular, opens up new possibilities for continuously monitoring pets' health statuses such as dogs/cats healthy, toxic ingestions, and swallowed. The domain adaptation frequently serves to provide related facilities to users. The topics discussed here are diverse and important in health administration and clinical practice. The pet mobile app can be used to keep pets disease-free. We can contact a pet specialist in an emergency by making an appointment online through this app. This app can assist you in locating the nearest pet hospital in your area. Pet health issues are addressed using mobile phones in this study
The Sagnac effect in optic fiber link synchronization of high-precision frequency standards
Authors: Mazurova E.M. , Petrov A.N.
Published: January 2023

This is the second of the two articles on the Sagnac effect, one of the main relativistic effects. Its idea is retarding (advancing) signals propagating in opposite directions throughout the perimeter of a rotating disc. In the first article its theoretical substantiation was presented. These calculations make the basis for this paper to be used for describing the effect under real conditions on the surface of the rotating Earth. An optical fiber is to distribute the signal. A relativistic equation is written for a wave propagating in an optical fiber, which is used on the Earth`s surface to synchronize high-precision frequency standards. This formula is analyzed, the level of contributions of various relativistic effects is estimated, and the Sagnac’s is singled out as the main one. A joint consideration of the theoretical foundations and the influence of the phenomenon in applied tasks will be good for solving the matter of synchronizing high-precision frequency standards in a complex way.
Rendering a regular grid of terrain elevations using WebGL and natural triangulation
Authors: Vasiliev N.P. , Vagizov M.R.
Published: January 2023

Two ways of rendering a regular terrain elevation grid using WebGL are considered