bluuebunny/crossref_metadata_2025 huggingface dataset:
Hydrolysis monitoring of Quinoa, Soy and Rice Proteins by using spectroscopy FT-IR technique
Authors: Roa Acosta Diego Fernando , Bravo Gómez Jesus Eduardo , Hoyos Concha Jose Luis
Published: July 2023

The proteins that are subjected to hydrolysis processes increase their bioactive and functional properties, for this reason, in this work the protein hydrolysis was monitored by means of spectroscopy, to determine the structural changes that proteins undergo during hydrolysis. Enzymatic hydrolysis with endo / exoproteases was carried out on the three protein isolates, the enzymes used were Alcalase 2.4L and Flavorzyme® from the Sigma laboratory. The enzyme / substrate ratio was 5%; degrees of hydrolysis between 46% and 38.4% were obtained for Quinoa protein isolate and Rice protein isolate, respectively. Both follow-up of Quinoa protein isolate and Soy protein isolate enzymatic hydrolysis was 60 minutes with Alcalasa®2.5L and 120 minutes with Flavorzima®, with respect to Rice protein isolate, the established hydrolysis times were 60 minutes with Alcalase 2.4L and 20 minutes with Flavorzima®; Times longer than these, no significant differences were observed in the degree of hydrolysis. By way of comparison, the protein isolates and their hydrolysates were studied in the mid-infrared range (4000 cm-1 to 600 cm-1) to obtain information on the structure of the protein, for this, a technique was used deconvolution of the spectrum by means of the Fourier transform function. These spectra showed significant differences in the secondary structure of the protein, regarding the analysis of the areas, which were determined using a Gaussian function; the most favorable changes were mainly in the formation of b-sheet and b-turns structures.
Mathematical model of a wave gear with the external deformation waves generator
Authors: Timofeev G.A. , Lyuminarsky I.E. , Lyuminarsky S.E.
Published: July 2023

The paper considers a spatial mathematical model of a wave gear with the annular generator of the external deformation waves. Calculation method was based on determination of the elastic interaction between flexible wheel, rigid wheel and wave generator. Numerical studies confirmed the adequacy of the proposed mathematical model. Theoretical studies of the influence of preload in the gearing and initial clearance between the flexible wheel and the deforming washers on the forces acting on the wave generator bearings were conducted. It is shown that a decrease in the specified clearance leads to an increase in loads on the bearings. By calculation, torsional rigidity characteristics of the wave gear with an external deformation generator were obtained for various interference values in the gearing and the clearance.
11С-methionine PET/CT use in the diagnosis of primary hyperparathyroisis
Authors: Pogosian K. A. , Karonova T. L. , Ryzhkova D. V. , Tsoy U. A. , Semenova A. N. , Yudina O. V. , Grineva E. N.
Published: July 2023

Background. Primary hyperparathyroidism (PHPT) is an endocrine disorder characterized by autonomous production of parathyroid hormone (PTH). Currently, parathyroidectomy (PTX) is considered the main method of PHPT treatment. Its outcome is largely depended on precise preoperative localization of the parathyroid adenoma. Traditional visualization techniques include ultrasound (US), scintigraphy and computed tomography (CT), each of which has its own limitations. In order to improve visualization results positron emission tomography/ computed tomography (PET/CT) with 11C-methionine is used. Objective. To compare the sensitivity and specificity of 11 C-methionine PET/CT with those of conventional imaging techniques for parathyroid adenomas localization.

Design and methods. The data of 91 patients diagnosed with PHPT was analyzed. Ultrasound, scintigraphy with 99mTc-sestamib i/99mTc-pertechnetate and CT were performed in 91, 56, and 86 patients, respectively. Since 2020, 11C-methionine PET/CT has been used as the final diagnostic method in 45 patients. Histologу results were used as the benchmark in order to evaluate the diagnostic accuracy of the studied methods.

Results. Histological examination confirmed parathyroid adenoma/ hyperplasia in all patients. Multiple adenomas/hyperplasia were found in 5 cases. Ectopic adenomas were detected in 19 patients. The sensitivity of PET/CT with 11C-methionine was 98 %, CT, scintigraphy and ultrasound — 75 %, 79 %, 67 %, respectively. Specificity — 93 %, 73 %, 75 %, 70 %, respectively.

Conclusion. 11C-methionine PET/CT showed higher sensitivity and specificity than traditional methods.
Еarly splenic response to ruxolitinib correlates with survival: a russian retrospective multicenter study in patients with myelofibrosis
Authors: Lomaia E. G. , Siordia N. T. , Kulemina O. V. , Strugov V. V. , Senderova O. M. , Ochirova O. Е. , Zhalsanova E. B. , Furtovskaya A. Yu. , Alekseeva Yu. A. , Lazorko N. S. , Sbityakova E. I. , Dimov G.  P. , Pozina M. G. , Li O. Yu. , Trizna K. B. , Mikhalev M. A. , Sokurova E. V. , Otmorskaya A. A. , Khazieva A. S. , Ustyantseva V. V. , Matvienko Yu. D. , Zaritsky A. Yu.
Published: July 2023

We retrospectively analyzed the effectiveness of ruxolitinib in patients with myelofibrosis (MF) in real clinical practice in Russia. The study included 42 patients with MF with an average age of 56 years from 10 inpatient and outpatient clinics. The majority of patients (55 %) belonged to the intermediate risk group 1 on the DIPSS scale, 86 % had massive splenomegaly and 88 % had constitutional symptoms. The average initial dose of ruxolitinib was 15 mg twice a day. At the time of analysis, 74 % of patients continued taking ruxolitinib with an average duration of therapy of 20 months. A decrease in the palpable size of the spleen by at least 50 % was recorded in 36 % and 46 % of patients assessed after 3 and 6 months of treatment, respectively. A correlation was found between OV, initial splenomegaly and splenic response after 3 months of therapy. It should be noted that no deaths were recorded in patients with a decrease in the size of the spleen by ≥ 50 %. There were no cases of discontinuation of treatment due to side effects. In general, in our retrospective study, ruxolitinib effectively controlled constitutional symptoms and reduced the size of the spleen in patients with MF. An early splenic response after 3 months of therapy is apparently a prognostic factor for OS, and a decrease in the size of the spleen by less than 25 % should be considered as treatment ineffectiveness in patients with MF taking ruxolitinib.
Ways to personalize the treatment of patients with relapse and continued growth of intracranial meningiomas
Authors: Kukanov K. K. , Ushanov V. V. , Zabrodskaya Yu. M. , Tastanbekov M. M. , Vorobyova O. M. , Sitovskaya D. A. , Dikonenko M. V.
Published: July 2023

Purpose. According to the literature, to assess the state of the problem of diagnosis and treatment of meningiomas with recurrent course, to identify the causes of tumor progression, features of the clinical picture, radiology diagnostics, the specificity of pathomorphological and molecular genetic characteristics.

Materials and methods. We searched for publications in the Pubmed, EMBASE, Cohrane Library and eLibrary databases published between January 2000 and January 2019 on the issue of recurrent intracranial meningiomas, in particular atypical and anaplastic.

Results. The review systematizes data on the prognostic criteria for diagnosing meningiomas that affect survival, relapse-free period, and the progression of the neoplastic process. Particular attention is paid to the radicality of the operation and the assessment of the degree of anaplasia. The present day information on radiation therapy and drug treatment is presented, the results of studies on their effectiveness are discussed. The controversial issues of approaches to the assessment of morphological prognostic criteria are touched upon. The latest information on the most common genetic mutations in meningiomas, the prospects for their study and use for targeted therapy are presented. The authors come to the conclusion that the problem of managing patients with meningiomas is still far from its final solution; there are no optimal standards for the diagnosis and treatment of patients with meningiomas, taking into account biological characteristics, including growth characteristics, molecular genetic profile. There are no clear prognostic criteria for recurrence and continuity in further supervision after surgical treatment, which cannot but affect the mortality rate and quality of life of this category of patients.
Hemorrhagic complications during stereotactic biopsy of brain tumors
Authors: Kukanov K. K. , Voinov N. E. , Peskov V. A. , Ulitin A. Yu. , Dikonenko M. V.
Published: July 2023

Relevance. Stereotactic biopsy (STB) is one of the main methods for diagnosing deep brain lesions. STB has several advantages over conventional intraoperative biopsy, as it is less traumatic and safer, especially for patients in critical condition. However, the most common complications of STB are hemorrhages, with a risk ranging from 0.9 % to 59.8 % depending on various studies. Intracranial hemorrhages are serious complications of surgical treatment of brain tumors, especially during biopsy using stereotactic techniques.

Objective. To assess the risk of intracranial hemorrhages during STB of brain tumors and investigate possible factors influencing this risk, such as involvement of different brain regions in the neoplastic process, patient’s gender and age, degree of malignancy of the tumor, and use of different stereotactic devices.

Materials and Methods. A retrospective study of data from 20 patients who underwent STB of brain tumors was conducted. Clinical data, examination results including coagulogram and aggregatogram, as well as data on involvement of different anatomical brain regions in the neoplastic process, degree of malignancy of the tumor, and use of a specific stereotactic device were analyzed.

Results. Analysis of the frequency and structure of hemorrhagic complications of STB was performed, prognostic factors for high risk were identified, and preventive measures were proposed to reduce the number of hemorrhages.

Conclusions. The introduction of the modern CRW Radionics stereotactic device into practice has reduced the frequency and severity of hemorrhagic complications after STB by two times. Lymphoproliferative processes and glioblastomas have a higher frequency of hemorrhages, but in most cases, they are clinically insignificant. There is a correlation between the degree of anaplasia of astrocytic tumors and the severity of hemorrhages. Ways to reduce the risks of intracranial hemorrhages during STB of brain tumors may include: careful preoperative planning of the biopsy trajectory; use of informative neurovisualization methods in planning the needle insertion trajectory; use of modern stereotactic systems by neurosurgeons who have undergone additional specialization and training on the specific device; use of modern biopsy needles. In addition, it is advisable to consider preoperative preventive hemostatic therapy in patients suspected of having a high degree of tumor anaplasia.
Molecular genetic bases and pathways of carcinogenesis in the pancreas
Authors: Solonitsyn E. E. , Seyfedinova S. Sh. , Kalinina O. V. , Freylikhman O. A.
Published: July 2023

Pancreatic cancer is a highly aggressive disease with a high mortality rate in need of innovative diagnostic and therapeutic approaches. In recent years, due to the development of molecular genetic methods a large amount of data has appeared on the genetic and epigenetic alterations that occur in pancreatic cancer, and the genetic landscape of this disease has been determined. Additionally, the genetic factors underlying the multistep carcinogenesis in precursor lesions of the pancreas have been clarified. This review highlights the pathways of carcinogenesis in the pancreas, as well as the molecular genetic processes underlying it.
FEATURES OF FORMATION, MATERIAL COMPOSITION AND GEOLOGICAL STRUCTURE OF RARE METAL AND PEGMATITE DEPOSITS OF THE KALBA REGION ON THE EXAMPLE OF THE YUBILEINOE DEPOSIT
Authors: Oitseva Tatyana A. , Dyachkov Boris A. , Bissatova Ainel Ye. , Orazbekova Gulizat B. , Zinyakin Stanislav S.
Published: July 2023

Link for citation: Oitseva T.A., Dyachkov B.A., Bissatova A.Ye., Orazbekova G.B., Zinyakin S.S. Features of formation, material composition and geological structure of rare metal and pegmatite deposits of the Kalba region on the example of the Yubileinoe deposit. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 7, рр. 164-176. In Rus.
The relevance of the research is caused by the lack of knowledge on the behavior of rare metal in pegmatite ore formation in the Kalba region and the need to expand the rare-metal mineral resource base of the region and to establish geological and mineragenic mapping. The main aims of the research are identification of features of geotectonic development, geological structure and material composition of the rare-metal deposit Yubileynoe (Kalba region). Study area: large industrial rare metal deposit Yubileynoe and its mineral complexes. Methods: detailed geological-geochemical and mineralogical study of the region of work, use of materials from works of previous years, stock literature, as well as laboratory studies (mass spectrometric, microprobe, geochronological and other studies). The structural relationships of minerals with each other, as well as the geochemical interpretation of the results of laboratory studies, were taken into account during diagnosing mineral complexes. Results. Spatial and genetic relationship of rare-metal pegmatite deposit (Nb, Ta, Be, Cs, Li, Sn) with granites of the I phase of the Kalba complex P1 (285 Ma), is distinguished. In the location of the Yubileinoe deposit, the leading ore-controlling role is given to the system of deep latitudinal faults of ancient origin, renewed in the Hercynian cycle. A geological and genetic model of rhythmically pulsating rare-metal pegmatite formation of the Yubileinoe deposit is presented, which reflects the zonal development of mineral complexes from oligoclase-microcline (barren) to albite, greisen, spodumene-containing and pollucite-bearing (ore) with an increasing concentration of mineralization. Information was obtained on the composition of pegmatite ores with the release of typomorphic minerals (clevelandite, lepidolite, colored tourmalines, spodumene, pollucite, ixiolite, etc.) and the main geochemical elements of rare metal ore formation (Nb, Ta, Be, Cs, Li, F, P, etc.).
FEATURES OF THE STRUCTURE AND NATURE OF POLLUTION OF THE UPPER PART OF THE SECTION OF OIL STORAGE FACILITIES IN THE VOLGA RIVER VALLEY
Authors: Mingaleva Tatiana A. , Shakuro Sergey V. , Egorov Alexey S.
Published: July 2023

Link for citation: Mingaleva T.A., Shakuro S.V., Egorov A.S. Features of the structure and nature of pollution of the upper part of the section of oil storage facilities in the Volga River valley. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 7, рр. 137-147. In Rus.
The relevance of the study is caused by the fact that soil pollution with oil products has a complex dynamic character in the spatio-temporal region. Therefore, the physical properties of soils in solving geophysical problems of contouring and determining the thickness of pollution can change under the influence of various factors, expanding the range of search signs of pollution. Determination of physical parameters for areas of oil pollution, similar in nature of development and geological conditions, can help in the future for the effective parameterization of hydrocarbons in soils. The main aim is to build a generalized model with physical properties (electrical resistivity, сompressional and shear-wave velocities) for the soils of long-term oil depot territories. Methods: analysis of literary sources on the research topic; processing and interpretation of field geophysical material for tank farms located on the banks of the Volga River; building a generalized model with a description of the physical characteristics of soils based on the results of geophysics for the soils of tank farms. Results. The authors have studied the nature of soil pollution of two oil depots in the Volga River region using materials published in domestic and foreign literature, which made it possible to substantiate the parameters of a generalized physical-geological model of soil pollution of oil depots. In the general case, the distribution of pollution areas is subject to the features of the geological structure and hydrogeological regime of the areas under consideration and generally includes five zones (the upper area, the area of pollution above the free-flow horizon, the area of seepage in the hydrogeological window, the area of groundwater pollution, the zone of secondary accumulation). This model can be used to predict the nature of pollution in tank farms, loading and unloading points, car repair shops, washing sites and gas stations located near river and lake basins. The model of distribution of oil products in soils will be complex, which will also be expressed in geophysical sections.
RATIONALE FOR SELECTING SAND FILTERS FOR PRODUCTION WELLS
Authors: Khabibullin Marat Ya. , Khabibullin Arsen M.
Published: July 2023

Link for citation: Khabibullin M.Ya., Khabibullin  A.M. Rationale for selecting sand filters for production wells. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 7, рр. 26-34. In Rus.
The relevance of the study are caused by the need to ensure the flow of more purified reservoir fluid into the bottomhole zone of the well. When opening a formation with production wells, the design of which includes anti-sand filters, there are some imperfections that are characterized by the degree and nature of its opening and are caused by the designs of casing filters. For a rational choice of an anti-sand filter in a well, it is necessary to conduct experimental bench studies, taking into account well conditions. Purpose: based on the results of experimental studies, propose the optimal design of the anti-sand filter. To select, it is necessary to take into account the hydraulic parameters of its operation, which can be determined based on the bench tests of two types of filter elements: block and frame-rod with wire winding, in open and cased hole conditions, as the most promising in terms of application. Objects. To accomplish this task, a stand was created that allows you to: determine the amount of fluid passing through with sand; the volume and granulometric state of the sands that pass through the filters when filtering the mixed liquid; state and change in the structure of rocks in the bottomhole zone of the well; distances between the filter elements and the production casing, the performance of the sand filter. The main component of the stand is a combined-shaped filtration tray imitating a circular reservoir model. Methods. The working fluid (oil), preheated to a predetermined temperature with the help of a heating element, is supplied to the filtration tray by a pump from the receiving tank through the pressure manifold. The temperature of the working fluid in a given mode is maintained using a non-contact controller. The discharge pressure is measured with a manometer. The pressure manifold is fitted with a spring-loaded relief valve. The change in pressure of the radial flow of the working fluid in the filtration tray is recorded by a pressure sensor. The working fluid from the filtration tray is passed through a cleaning system made in the form of two cylinders, in which there are sieves for trapping and screening sand particles with a size of 0,005 mm or more. The purified working fluid again enters the receiving tank. Results. Block and single-layer wire filters while ensuring a small amount of sand are quickly clogged. The double layer wire filter has the highest peak resistances and occasional significant sand production. Obviously, it can be recommended for flowing oil production, with a significant excess of reservoir pressure in relation to hydrostatic pressure.
ANALYSIS OF CHANGES IN GROUNDWATER LEVELS IN QUATERNARY DEPOSITS IN THE SOUTH-EASTERN PART OF THE IRTYSH-OB ARTESIAN BASIN
Authors: Balobanenko Andrey A. , Vasilyev Denis I. , Dutova Ekaterina M. , Kuzevanov Konstantin I.
Published: July 2023

Link for citation: Balobanenko A.A., Vasilyev D.I., Dutova E.M., Kuzevanov K.I. Analysis of changes in groundwater levels in quaternary deposits in the south-eastern part of the Irtysh-Ob artesian basin. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 7, рр. 202-213. In Rus.
Relevance. The tasks of studying the level regime of groundwater are very closely related to the need to predict their resources under the influence of both natural and artificial factors in order to develop scientific foundations for the rational use of water resources and effective management of the groundwater regime in the study area. Purpose: to study changes in the level regime of groundwater for domestic and drinking purposes in Quaternary deposits in the south of the West Siberian artesian basin based on the results of long-term regime observations. Objects: groundwater of the Irtysh-Ob artesian basin of the II order, the southeastern part of the West Siberian artesian basin of the I order, most actively involved in the sphere of anthropogenic activity. The study area is confined to a province with stable seasonal freezing of the aeration zone, where the main groundwater recharge is carried out in the spring due to snowmelt. Methods. The methodology for conducting observations of groundwater levels was determined by the regulations of the former USSR Ministry of Geology, and then the Ministry of Natural Resources of the Russian Federation, this paper presents a statistical processing of time series of observations of groundwater levels and a comparison of the results obtained with the data on the water regime of surface watercourses and climatic characteristics of the study areas. Results. The leading influence of climatic conditions on the main regularities of the natural hydrodynamic regime of groundwater was revealed. A different degree of intensity of the influence of external factors is shown, expressed by the amplitude of the groundwater level, depending on the type of groundwater regime and the degree of moistening of the territory. Natural factors have the least effect on groundwater as they move away from draining ones and with increasing depth.
CALCULATION OF THERMODYNAMIC AND KINETIC PARAMETERS OF CATALYTIC CRACKING REACTIONS ON LEWIS AND BRØNSTED ACID SITES
Authors: Nazarova Galina Y. , Ivashkina Elena N. , Maltsev Vladislav V.
Published: July 2023

Link for citation: Nazarova G.Y., Ivashkina E.N., Maltsev V.V. Calculation of thermodynamic and kinetic parameters of catalytic cracking reactions on Lewis and Brønsted acid sites. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 7, рр. 214-225. In Rus.
The relevance of the research is caused by the emerging necessity of developing a mathematical model to optimize the heterogeneous process of catalytic cracking. This tools should take into account both the chemical transformations of a wide range of hydrocarbon groups (different feedstock types), as well as the stages of adsorption, reactants diffusion, conversion of hydrocarbons on the catalyst surface, acid characteristics and pore size of the catalysts. The study of the hydrocarbon conversion patterns on Lewis or Brønsted acid sites using quantum-chemical modeling methods allow us to quantify the thermodynamic parameters of reactants adsorption, the kinetic parameters of carbocations formation and cracking on acid sites. These results are necessary to develop a mathematical model based on the of heterogeneous catalytic reaction mechanism. The aim of this work is to identify the level of quantum chemical theory and to determine the thermodynamic and kinetic parameters of reactants adsorption, carbenium ions formationand hydrocarbons cracking on Lewis and Brønsted acid sites. Methods: quantum-chemical modeling methods to optimize the molecular geometry of reactants and products of catalytic cracking reactions, calculate vibrational frequencies, thermodynamic parameters of adsorption and catalytic cracking of hydrocarbons and heteroatomic compounds with the participation of Bronsted and Lewis acid sites. Results. The chosen level of quantum-chemical theory allowed obtaining the results that are consistent with the laws of the process and the experimental reactivity of hydrocarbons in cracking reactions on acid catalysts. The thermodynamic parameters of the adsorption of C6–C16 hydrocarbons and thiophenes on Lewis and Brønsted acid sites were identified. We found that during the cracking of n-hexane on the Lewis acid site, the reaction is limited by the carbenium ion formation stage.The activation energy of this stage was 281,3 kJ/mol whereas the value for the cracking stage was 277,2 kJ/mol. Further study shows that the activation energy of carbenium ion formation from izohexane and C8–C10 alkanes with normal structure on the Lewis acid site was 257,6 and 279,2…277,9 kJ/mol. The most energetically favorable is the formation of carbocation from hexene at Brønsted acid sites (76,59 kJ/mol). The results of the work will be used to create a mathematical model of a heterogeneous process based on the Langmuir–Hinshelwood equations.
Perkembangan Madrasah dan Tingkat Kepercayaan Publik
Authors: As'ari As'ari , Nugraha Enung
Published: July 2023

Madrasah developed every decade for Indonesia society. The development of Madrasah runned along with the need of family household. Madrasah sustained the quality as well as provided more deep practices and extra-curricular to support prominent programs. This research describes deeply of madrasah development and society or public trust sustainably to madrasah. This study is descriptive qualitative research designed by naturalistic inquiry to naturalistic phenomena of Islamic education. The data collecting techniques are observation and interview by which data analytical inductive analyses, creative synthesis and holistic perspective to education phenomena and stakeholders. The result of the study shows that in modern and industrial era 4.0, stakeholders respond to what society need to industrial world rather than just believing the truth of self-sense to religious touches. The quality and public trust, on education in Madrasah, increase. Madrasah strives to improve the significant plays a role of state Madrasah as a model and as a controller of the quality of Madrasah taught. Developing educational programs and improving the ability of madrasahs to bring the role as public schools based on Islamic characteristics creates graduates’ quality as social expectations.
Implementation of Islamic Boarding School Socio-Cultural Management-Based Curriculum in Developing of Islamic Educational Institutions Quality
Authors: Chotimah Chusnul , Khusna Nur Isroatul , Amin Saiful , Palupi Catur
Published: July 2023

The design and implementation of the educational curriculum must be adapted to the socio-cultural conditions of an educational institution. Therefore, in implementing the curriculum, it is better to use appropriate socio-cultural management so that quality development goes well even though it is in educational institutions that have a strong religious system or known as pesantren. The purpose of this research is to know the planning, implementation and evaluation of curriculum based on socio-cultural management in the area of pesantren-based social institutions. This research is a qualitative with the type of case study. Sources of data used are primary and secondary. Data collection techniques in the form of observation and interviews. Data analysis used qualitative data analysis according to Miles and Huberman. The result of this research is that curriculum planning carried out by MTs Nurul Iman Garum is carried out with a process towards a better direction in terms of learning and institutions. In addition, the implementation of the curriculum includes checking teacher readiness, the learning process is supervised by the head of the madrasa, there is an instillation of Islamic values in the learning process, implementing the ubudiyah program, the tahfidz program or additional tutoring. For the evaluation carried out by the MTs Nurul Iman Garum institution, namely; there are two evaluations to measure students' abilities, namely summative and formative evaluations.
Crisis in Sudan: Briefing Note on Displacement from Sudan to South Sudan
Authors: Pendle Naomi , Palmer Jennifer , Parker Melissa , Caesar Arkangelo Nelly , Diu Gatket Machar , Moro Leben
Published: July 2023

The experiences of those fleeing from Sudan to South Sudan due to the current conflict are shaped by the complex socio-political dynamics within and between the two countries. This briefing (published 28 July 2023) focuses on the historical and socio-political dynamics that need to be taken into consideration by humanitarian agencies when they are providing assistance and protection to South Sudanese fleeing from Khartoum and other parts of Sudan to South Sudan, and to Sudanese fleeing Sudan to seek refuge in South Sudan. This briefing note was prepared by Naomi Pendle, Jennifer Palmer, Melissa Parker, Nelly Caesar Arkangelo, Machar Diu Gatket and Leben Moro. It draws on recent personal experiences, established research connections and emerging information about the evolving situation in both countries.
Responsabilidade Social Corporativa: Uma Análise das Grandes Empresas do Setor de Agronegócio no Brasil
Authors: Boraschi Machado Maria Eduarda , De Melo Conti Diego , Castañeda Ayarza Juan Arturo , Da Silva Filho Candido Ferreira
Published: July 2023

Objetivo: analisar as ações de responsabilidade social das grandes empresas setor de agronegócio no Brasil a fim de compreender de que maneira estão lidando com questões de sustentabilidade
Método: esta pesquisa é classificada como documental e exploratória com abordagem qualitativa, utilizando a técnica de análise de conteúdo para o tratamento dos dados.
Principais resultados: os resultados analisam e comparam políticas voltadas para a gestão do meio ambiente, bem-estar animal, gestão social e governança corporativa da JBS, Raízen Energia, Cosan, Ambev, e Marfrig Global Foods.
Relevância/originalidade: o estudo tem caráter inédito e apresenta uma análise das políticas de sustentabilidade em um dos segmentos mais relevantes para a economia brasileira.
Contribuições teóricas/metodológicas: o estudo contribui para discussões sobre as políticas sustentáveis elaboradas por grandes empresas de agronegócio no Brasil, interpretando a maneira como elas são colocadas em prática e como as empresas se beneficiam disso.
Optimization of the proximal sealing in thoracic endovascular aortic repair (TEVAR)
Authors: Squizzato Francesco , Spertino Andrea , Grego Franco , Antonello Michele , Piazza Michele
Published: July 2023

Thoracic endovascular aortic repair (TEVAR) today represents the first option for the treatment of most pathologies involving the descending thoracic aorta. Proximal endograft failure, which includes endograft migration or type IA endoleak, represents the most frequent complication during the mid-term and long-term period. Proximal sealing length is the single most important factor affecting the technical success and durability of TEVAR. Other factors related to aortic arch anatomy, fluid dynamics, type of endograft, or type of pathology, may influence the risk of proximal endograft failure, and should be considered during the endovascular planning of the proximal sealing length. This review summarizes the evidence on the factors affecting the risk of proximal endograft failure, and provides the rationale for the choice of the proximal sealing length during TEVAR, based on specific patients’ characteristics.
The impact of gender-based violence on girls in the selected secondary schools in Limpopo, South Africa
Authors: Rammbuda Mulatedzi Calvin
Published: July 2023

The crucial mandate for any state is that learners attain their education in a safe learning environment. Learners’ access to a high-quality, inclusive, equitable education, and their capacity are jeopardised by the pervasive gender-based violence in and around schools. This paper aims to investigate the impact of gender-based violence on girls in the selected secondary schools in Limpopo Province of South Africa. From the qualitative standpoint, coupled with the case study research design, this study used a purposive sample to select 15 (n = 15) participants. Data were collected through literature reviews and the application of semi-structured Key Informant Interviews and analysed using Thematic Analysis. The findings of this study include (i) low school performance, (ii) learners who are dropping out, (iii) learners’ inability to exercise their human rights and their right to an education, (iv) lack of a well-resourced and strong criminal justice system, and (v) an intervention team to address the impact of gender-based violence on girls. This study concludes that gender-based violence should be taught as a subject in schools to address the persistent issue in South Africa for learners to understand abuse and violation in the future. This paper recommends that all stakeholders in our society—civil, social workers, and law enforcement authorities—collaborate more closely than they currently do to end gender-based violence against schoolgirls.
Employee performance as mediated by organisational commitment between transactional leadership and role ambiguity
Authors: Arif Andriansyah Mochamat , Sudiro Achmad , Amanah Jiwa Juwita Himmiyatul
Published: July 2023

This study examines and analyzes the effect of transactional leadership and role ambiguity on employee performance as mediated by organizational commitment. This study uses a quantitative approach. The population in this study was full employs at the Pabrik gula Ngadirejo factory. Technique sampling using proportionate random sampling. Questionnaires were distributed to Ngadiredjo Sugar Factory Kediri employees, with 125 respondents. The data analysis technique uses SEM analysis and analysis tools with the help of Partial Least Square (PLS). This study showed that transactional leadership and role ambiguity do not significantly affect employee performance. However, transactional leadership and role ambiguity significantly affect organizational commitment. Organizational commitment also has a significant effect on employee performance. Organizational commitment can mediate the effect of transactional leadership and role ambiguity on employee performance. The results of this study suggest that the sugar factory company continues to increase organizational commitment and make employees feel comfortable because the more robust sense of commitment to the organization will improve employee performance.
Influence of customer experiences on the preference for online bus booking services in Dar es Salaam, Tanzania
Authors: Bwemelo Gordian , Mashenene Robert
Published: July 2023

This study examined the influence of customer experience on the preference for online bus booking services in Dar es Salaam, Tanzania. Specifically, the study aims to: i) Determine the influence of familiarity with online booking services on the customer preference for online bus booking services, ii) Examine the influence of perception on the customer preference for online booking services, iii) Examine the influence of customer satisfaction on the customer preference for online bus booking services. The study employed a convergent parallel research design whereas both qualitative and quantitative data were collected. A sample of 384 users of buses for their transport was involved using a questionnaire that was administered through Google form as one of the web-based tools. Qualitative data were analyzed using content analysis whereas quantitative data were analyzed using descriptive statistics whereas mean scores, standard deviations, frequency, and percent were computed. Further, a binary logistic regression model was performed to analyze quantitative data. The findings show that customer perception and satisfaction were statistically significant in influencing customers’ preference for online bus booking. The study recommends to all key players in the bus transport sector make use of the findings to enrich policies and strategies in the adoption of online bus booking.
Gender-based violence as the outcome of maleness and egotism among Congolese male migrants located in the South African City of Durban
Authors: Ndabuli Theophile Mugisho  , Umumararungu Christine Kapita
Published: July 2023

The study investigates the relationship between masculinities, narcissism, and gender-based violence (GBV) among Congolese male refugees in Durban, South Africa. The research uses a qualitative approach and 25 in-depth interviews to identify major themes. Results show that Congolese male refugees reinforce their masculinities through narcissistic behaviors, which contribute to GBV. Societal stakeholders in Durban should be involved in addressing GBV prevention initiatives to hinder men's narcissistic attitudes and beliefs. Recognizing a partner's depth can help reduce GBV by recognizing the positive attention they expect from them.
The role of entrepreneurship education in mediating the effect of entrepreneurial orientation and self-efficacy on entrepreneurial intentions:
Authors: Fahmi Salam Abdulloh , Pardiman  , Eka Farida
Published: July 2023

This study aims to analyze the role of entrepreneurship education in mediating the effect of entrepreneurial orientation and self-efficacy on entrepreneurial intentions. The sample is the students at the Assalam Islamic Boarding School, Pasuruan Regency, consisting of 104 respondents. Questionnaires were distributed via google form as direct data collection from respondents. Then the data were analyzed using the partial least square structural equation model (SEM-PLS), which was then used to answer the research hypothesis. The results of the study show that directly entrepreneurial orientation is not able to increase interest in entrepreneurship. However, self-efficacy can increase interest in entrepreneurship. Furthermore, entrepreneurship education succeeded in mediating the influence between entrepreneurial orientation and self-efficacy on students' entrepreneurial interest in entrepreneurship.
The role of accountability in strengthening business sustainability: An Islamic perspective
Authors: Hatta Zulhelmy M. , Abrar Nawas  , Firdaus A.Rahman
Published: July 2023

This study aims to investigate and examine the role of accountability in strengthening business sustainability from an Islamic perspective. This research methodology uses qualitative methods and uses literature and documentation study techniques. The research data came from secondary data sources, based on literature studies, and were analyzed descriptively and qualitatively with emphasis on the use of scientific logic. The results of the study found that Islam is a system of life that regulates all aspects of life both in ritual matters such as faith (aqidah) and worship, as well as covering mu’amalah, activities that regulate the way of life of fellow human beings to meet the needs of everyday life issues such as government politics, economics, education, and social systems, including related to how accountability must be realized in a business or company. The accountability mechanism that is carried out must prioritize the principle of trust, especially in working with both subordinates who are given the mandate and superiors who give the mandate and are carried out as worship to Allah SWT. At the level of society and the state, Islam also regulates how accountability must be realized in the administration of the state by a leader or caliph. A leader will be held accountable both horizontally and vertically. Therefore, the results of this research are expected to be used by stakeholders including the government, legislators, academics, practitioners in both profit and non-profit organizations, and other interested parties, especially regarding the role of accountability in strengthening business sustainability in an Islamic perspective.
It's like an uncontrollable demon in your body: The lived experiences of youth using crystal meth during the COVID-19 pandemic in Witbank, Mpumalanga
Authors: Thembinkosi Peter Singwane  , Dillo Justin Ramoshaba
Published: July 2023

Crystal methamphetamine (meth) is quickly becoming one of the most used synthetic drugs worldwide, adding to the growing pandemic of substance abuse worldwide. Crystal meth may cause serious health effects including infertility, cancer and even DNA damage, especially among long-term users. Crystal meth users are often not aware of the serious health implications caused by crystal meth until it’s too late. This qualitative research paper employed the phenomenological research design to explore and describe lived experiences of crystal meth users. A total of 11 crystal meth users in the Witbank hotspots were identified through purposive convenience and key informants sampling. Data was collected through semi-structured interviews and the thematic content analysis was used for analysis. The study's findings reveal that crystal meth users have an uncontrollable urge to use the substance which results in them being stigmatized in society and negatively affecting their family functioning. The findings also show that some crystal meth users engage in criminal activities. There is a need for further studies on lived experiences across all types of drugs. Policymakers in South Africa should work towards an Instant-admission policy for people who use substances, through the capacity of social workers.
Motorcycles delivery innovation and performance of wholesale retail sector in Kenya
Authors: Kinyua Wanjau Christopher , Gichuhi D. M  , Kiambati K.
Published: July 2023

In Kenya, the wholesale and retail sector has been undergoing a difficult time that has seen some of the big retailers closing due to myriad challenges in their performance in the dynamic environment. This study sought to establish the influence of motorcycle delivery innovation on the performance of the wholesale and retail sectors in Kenya. The study was anchored on social exchange theory. The research philosophy adopted for the study was positivism. A descriptive research design using a quantitative approach was used in this study. The study targeted all wholesale and retail shops in 47 counties in Kenya that employed commercial motorcycles for their last-mile delivery of goods. Systematic sampling and simple random sampling techniques were employed to select a sample size of 383 respondents and a questionnaire was used to collect data. Descriptive and inferential analysis was undertaken across all variables using SPSS software. The findings indicated that there was a strong relationship between delivery innovations and the performance of the wholesale and retail businesses in Kenya (0.785). On the hypotheses, the study found that motorcycle delivery innovation had a statistically significant influence on the performance of wholesale and retail businesses in Kenya (t = 16.560, p=0.000 <0.05). The study concluded that motorcycle delivery innovations/solutions have a strong and statistically significant relationship with the performance of wholesale and retail businesses. The study recommends that wholesalers, retailers, and motorcyclists to have collaboration as they have mutual benefits. The study suggests that another study can be conducted to investigate the influence of embracing motorcycles by online businesses on their performance and growth.
Predicting intention to adopt omnichannel retailing of SMEs in Indonesia using UTAUT: the moderating role of personal innovativeness
Authors: Syahreza Alvin Erzal , Wahdiyat Moko  , Mintarti Rahayu
Published: July 2023

This study seeks to explain the intent of SMEs business owners to implement omnichannel retail in their operations. This study employs the UTAUT model and adds innovativeness as a variable that can influence the intention to adopt an omnichannel. The sample for this research consisted of 90 SMEs proprietors in Malang City. This study's data were gathered via a questionnaire and analyzed using PLS-SEM. This study found that personal innovativeness and performance expectations significantly influence the intention to adopt omnichannel. In this study, effort expectations have no significant effect on the intention to implement omnichannel. It has been demonstrated that personal innovativeness can moderate the relationship between effort and performance expectations in the UTAUT model when it comes to the intention of MSME proprietors to implement omnichannel. In addition to focusing on consumers as end users, this study concludes that omnichannel service providers must also consider enterprises as omnichannel users.
The Main Trends in the Development of the UK Party-Political System after the 2019 General Parliamentary Elections
Authors: Kovalev I. , Nazaruk T.
Published: July 2023

The 2019 general parliamentary elections in the UK took place in the context of a prolonged socio-political crisis: it was the second early election in three years, which is extremely atypical for Britain. Elections were held after resignation of T. May, who after several attempts failed to get support for her draft Agreement on Britain's withdrawal from the EU in the House of Commons and decided to leave the post of prime minister and leader of the Conservatives. Shortly after the victory of the Tories, the exit of the country from the EU, which was the main stumbling block in political discourse for three whole years, was finally completed by the new Tory leader B. Johnson. Then it seemed that the main contradictions had been overcome, but the coronavirus pandemic became another test of strength for the country's political system, and B. Johnson himself fell into a series of scandals that led not only to a declining trust in the prime minister, but to his resignation. Against the backdrop of instability in the political life of the country, the role of regional parties has also changed, which, as forces of opposition pressure, have a significant impact on the domestic political agenda. This article examines features of the development of the UK party-political system on the eve and after the 2019 general parliamentary elections. First of all, attention is paid to analyzing the election results, to the study of B. Johnson's policy in a period of crisis, the assessment of the approaches of the Labour Party under K. Starmer, and the analysis of the transforming role of regional parties in the country. The article also highlights the factors in the development of the modern party-political system in Great Britain. The main conclusion of the article is that despite the deep and prolonged political crisis in the country, the system remains stable and, moreover, the Conservative Party manages to maintain its dominance in these circumstances.
Generalized Ostrowski type results for twice differentiable functions on fractal sets
Authors: Erden Samet
Published: July 2023

We first obtain a new auxiliary identity by utilizing twice differentiable functions on α−type sets. Afterwards, two
generalized Ostrowski type estimations for mappings whose second local fractional derivatives are bounded are derived, and special
cases of these comprehensive inequalities are observed. Finally, some related applications such as inequalities including special means
and generalized quadrature rules are presented.
Simpson type integral inequalities for generalized strongly convex functions and applications
Authors: Erden Samet
Published: July 2023

We firstly establish an identity of Simpson type involving local fractional integral. By using the obtained result, some new
Simpson type integral inequalities for mappings whose certain powers of the local fractional derivatives in modulus are generalized
strongly convex are derived. Finally, some error estimations for local fractional integrals and inequalities involving generalized special
means are given.