bluuebunny/crossref_metadata_2025 huggingface dataset:
Neonatal transitional care: what it is and isn't
Authors: McEwan Tom
Published: June 2020

Tom McEwan, midwifery lecturer and honorary advanced neonatal nurse practitioner, considers the benefits that transitional care can provide to the neonate, their family and healthcare professionals
The Poole approach to a smoke-free pregnancy
Authors: Croucher Heidi , Ireland Jillian
Published: June 2020

Smoking tobacco is both a pharmacological addiction and a serious social and public health issue. Smoking cessation services for pregnant women save babies' lives and have the potential to improve the health of families and communities. Engaging with pregnant smokers and their households towards quitting smoking requires a whole-team approach. Protected time for the specialist smoking in pregnancy team and freedom to develop the service improvement approach has been key in the setting described in this paper. The approach to smoking cessation described in this paper is of the quality improvement arm within the ‘Saving babies' lives’ bundle of interventions in Poole Hospital NHS Foundation Trust. The ‘plan, study, do, act’ model is described with a description of its implementation using sequential learning, enquiry, testing and being open to new ideas and approaches. The main driver questions have been: ‘how do we reach pregnant smokers who are not motivated to quit?’ and ‘what approaches will potentiate success for this group?’
Building empathy
Authors: White Hilary
Published: June 2020

In the final part of this series, Hilary White explores how socio-emotional development can help all children to develop positive relationships with themselves, others and their environment.
Communicating change
Authors: Marsh Sian
Published: June 2020

Sian Marsh flags up the importance of keeping parents in the loop and being guided by the principles of the EYFS as childcare providers make changes to the way they operate.
Keep an open mind
Authors: Allingham Sue
Published: June 2020

The final part of this series unpicks what the new goals for personal, social and emotional development mean for practice and flags up the pitfalls of focusing too heavily on what is ‘expected’.
Stay on the page
Authors: Quigley Alex
Published: June 2020

Alex Quigley explores the key issues underpinning his latest professional book, Closing the Reading Gap. In it he focuses on how to identify where children are struggling and provides practical strategies to support their reading progress.
Natural rhythm
Authors: Clarke Jenni
Published: June 2020

Use the book Giraffe's Can't Dance to ignite children's interest in the rhythm and sway of dance moves, giving them confidence to lose themselves in the moment.
Preparing for school
Authors: Rawstrone Annette
Published: June 2020

Parents may be particularly worried at this time about the prospect of their child starting a new school but there is a lot they can do to smooth the transition.
Critical Incidents: Exploring EFL Prospective Teachers’ Teaching Experiences
Authors: Megawati Fika , Mukminatien Nur , Anugerahwati Mirjam , Indrayani Ninuk , Unsiah Frida
Published: June 2020

Investigating critical incidents is one way to assist prospective teachers in expressing any developmental stage when accomplishing the teaching practice program. It is a significant component of reflective teaching in an educational framework related to continuing professional development (CPD), particularly self-directed learning. This study aims at exploring EFL prospective teachers’ field experience in cultivating their teaching competence through a critical incident analysis. A qualitative approach was applied. Three participants with different levels of English proficiency took part in this study by sharing their experiences through participating in and answering an interview and an opinionnaire. To analyze the data from the instruments, this study used descriptive analysis and coding techniques respectively. Results indicate that both negative and positive critical incidents contribute to the participants’ teaching development. The incidents support the learning process towards becoming a teacher and assist shaping their awareness of teacher identity. Further, the result of this study reveals that English proficiency level seems to take part in the strategy used for identifying critical incidents. This study implies that critical incidents provide a chance for prospective teachers to be more reflective. Thus, teacher education program stakeholders need to support critical incident analysis by giving relevant assignments while they are doing teaching practice, which in turn builds professional development in the context of prospective teachers.
Developing Expertise in Teaching Students With Extensive Support Needs: A Roadmap
Authors: Ruppar Andrea L. , Roberts Carly A. , Olson Amy J.
Published: June 2020

Expertise among teachers of students with extensive support needs is not well understood, and beliefs about what constitutes quality education for this population vary widely. We discuss findings from prior research on teacher preparation in relation to high-leverage practices and expertise development for students with extensive support needs within the social contexts of schools. We identify four core practices of expert teachers for students with extensive support needs, and we theorize the progression from novice to expert for each core practice using Dreyfus's (2004) model of expertise.
National Research Goals for Social Inclusion of People With IDD
Authors: Bogenschutz Matthew , Amado Angela , Smith Cindy , Carter Erik , Copeland Mauretta , Dattilo John , Gaventa Bill , Hall Sarah , McManus Mark , Quraishi Sabra , Romer Lyle , Walker Pamela
Published: June 2020

Social inclusion for people with intellectual and developmental disabilities (IDD) is an issue of emerging importance in research, policy, and practice. Though strides have been made to improve community living, inclusive education, and improved employment opportunities for many individuals with IDD, social inclusion has been slower to evolve. A diverse group of stakeholders met at the National Goals 2015 Conference to develop the following set of goals designed to promote better social inclusion in the next 10 years: (a) develop measures for social inclusion, (b) examine how personal and community contexts shape inclusion, (c) embed measures of inclusion in research about other life domains, (d) build capacity for social inclusion, (e) identify best practices for promoting inclusion from the community perspective, and (f) understand life course trajectories that impact inclusion. The goals are discussed in more detail in this article.
Long-Term Services and Supports
Authors: Owen Randall , Bonardi Alexandra , Bradley Val , Butterworth John , Caldwell Joe , Cooper Robin , Eisenberg Yochai , Ford Marty , Hewitt Amy , Larson Sheryl A. , Rizzolo Mary Kay , Rotholz David , Stewart Chris , Terrill Beth , Ficker Terrill Cathy
Published: June 2020

People with intellectual and developmental disabilities (IDD) often rely on long-term services and supports (LTSS) to live and work in the community or with their families. As policy reforms continue, it is important that we have research goals to guide the field. In August 2015, an expert panel met to discuss the future of LTSS for people with IDD and reached consensus that future work should ensure adequate funding and quality standards are in place, especially with the growth of managed long-term services and supports (MLTSS) programs, the increasing variety of Medicaid funding authorities used to finance supports for people with IDD, the changes in public policy regarding LTSS, and the application of behavioral supports, particularly positive behavior support (PBS).
Second-harmonic generation in periodically poled silicon waveguides with lateral p-i-n junctions: publisher’s note
Authors: Franchi Riccardo , Castellan Claudio , Ghulinyan Mher , Pavesi Lorenzo
Published: June 2020

This publisher’s note contains corrections to Opt. Lett.
45, 3188 (2020)OPLEDP0146-959210.1364/OL.391988.
Doping B(C6F5)3 into poly[N,N‘-bis(4-butylphenyl)-N,N’-bis(phenyl)benzidine] for efficient quantum dot light-emitting diodes: balancing electron-hole injection and diminishing parasitic resistance
Authors: Yang Min , Zhang Qin , Shen Huaibin , Chang Chun , Gong Dongfei , Qin Yuancheng , Hao Zhongqi , Hai Xia , Li Fangfang , Zhou Dan , Zhang Yubao
Published: June 2020

Low hole mobility and poor film quality always result in poor performance of quantum dot light-emitting diodes (QLEDs). As a p-type dopant into the hole-transport layer (HTL) of the poly[N,N‘-bis(4-butylphenyl)-N,N’-bis(phenyl)benzidine](poly-TPD), B(C6F5)3 is used in hole mobility and film quality improvement for QLEDs. The results show that the hole mobility of the B(C6F5)3 doped poly-TPD layer is risen by 31.6% and excess electron injection is suppressed to balance electron-hole injection. At the same time, B(C6F5)3 doping improves the film quality of both the HTL and quantum dots emitting layer, the parasitic resistance of QLEDs is diminished. The turn-on voltage of the device is reduced from 2.6 V to 2.3 V, and the brightness and current efficiency are increased by 26% and 35.4%, respectively.
Polarization-enhanced AlGaN solar-blind ultraviolet detectors
Authors: Jiang Ke , Sun Xiaojuan , Zhang Zi-Hui , Ben Jianwei , Che Jiamang , Shi Zhiming , Jia Yuping , Chen Yang , Zhang Shanli , Lv Wei , Li Dabing
Published: June 2020

AlGaN solar-blind ultraviolet detectors have great potential in many fields, although their performance has not fully meet the requirements until now. Here, we proposed an approach to utilize the inherent polarization effect of AlGaN to improve the detector performance. AlGaN heterostructures were designed to enhance the polarization field in the absorption layer, and a high built-in field and a high electron mobility conduction channel were formed. As a result, a high-performance solar-blind ultraviolet detector with a peak responsivity of 1.42 A/W at 10 V was achieved, being 50 times higher than that of the nonpolarization-enhanced one. Moreover, an electron reservoir structure was proposed to further improve the performance. A higher peak responsivity of 3.1 A/W at 30 V was achieved because the electron reservoir structure could modulate the electron concentration in the conduction channel. The investigation presented here provided feasible approaches to improve the performance of the AlGaN detector by taking advantage of its inherent property.
Geometric-phase-induced arbitrary polarization and orbital angular momentum generation in helically twisted birefringent photonic crystal fiber
Authors: Fujisawa Takeshi , Saitoh Kunimasa
Published: June 2020

The evolutions of polarization and orbital angular momentum (OAM) states of light in helically twisted birefringent photonic crystal fibers (TB-PCFs) are analyzed. It is shown that a circular polarization (CP) component (

S
3

of a Stokes parameter) is periodically excited when usual linearly polarized (LP) modes of PCF are launched. The excitation originates from a geometric phase in TB-PCFs. The

S
3

excitation is larger for larger linear birefringence for a fixed twisting rate. If the linear birefringence is large enough, a CP filtering behavior can be seen in addition to the

S
3

excitation. From the analytical consideration of the sign of the geometric phase, the TB-PCF with periodical inversion of twisting is proposed to generate arbitrary polarization state on the Poincaré sphere. Next, an OAM state generation in multimode TB-PCFs is shown for higher-order LP mode input. By observing a far-field interference pattern from TB-PCF mixed with

LP
01

mode, a vortex associated with the OAM state can be seen. Similar to the single-mode case, by using periodical twisting inversion, efficient OAM generation is possible. These results indicate that by simply launching fiber’s LP mode into TB-PCF, arbitrary polarization and OAM states can be generated, leading to a novel mechanism for the manipulation of the spatial state of light.
An estranged gaze at the world of work: La mano invisible (Isaac Rosa 2011; David Macián 2016)
Authors: Gustrán Loscos Carmina
Published: June 2020

This article analyses the unusual representation of work and workers in the novel La mano invisible (Isaac Rosa 2011) and its cinematic version (David Macián 2016). It explores how Rosa and Macián challenge the hegemonic invisibility of labour and labourers in the collective imagination of Spanish society by materializing not only the invisible hand of the workers behind the production of commodities and the supply of services, but also the invisible hand behind labour relations in a neo-liberal society. These representations are also analysed in their context of production and reception: post-industrial Europe and, more specifically, post-2008 crisis Spain.
Crisis, Austerity and Transformation: How Disciplinary Neoliberalism Is Changing Portugal, Isabel David (ed.) (2016)
Authors: Noronha Ricardo
Published: June 2020

Review of: Crisis, Austerity and Transformation: How Disciplinary Neoliberalism Is Changing Portugal, Isabel David (ed.) (2016)

Lanham: Lexington Books, 195 pp.,

ISBN 978-1-49854-387-3, h/bk, $95.00
Smart City Barcelona: The Catalan Quest to Improve Future Urban Living, Antoni Vives (2018)
Authors: Calzada Igor
Published: June 2020

Review of: Smart City Barcelona: The Catalan Quest to Improve Future Urban Living, Antoni Vives (2018)

Eastbourne: Sussex Academic Press, 231 pp.,

ISBN 978-1-84519-918-0, h/bk, 1845199189 (e-Book), $31.80/$30.60
Learning from the history of alternative communication networks
Authors: Tréguer Félix , Trudel Dominique , Dulong de Rosnay Mélanie
Published: June 2020

This article explores the legal, economic and governance challenges to the sustainability of contemporary alternative Community Networks by drawing lessons and parallels from eight historical precedents. Building on academic literature related to alternative and community media, the article lays out an encompassing definition of alternative networks (or ‘alternets’) and develops a multidisciplinary approach to comparative history. After briefly presenting eight case studies (three independent telephone networks of the late nineteenth century; three Free Radios of the 1950s, 1960s and 1970s; two Community Networks providing Internet access in the 1990s), the article then draws from these case studies to identify key recurring challenges that can inform present-day initiatives, namely, the articulation of local community with global connectivity, the development of political advocacy capacities aimed at influencing the law and technology, the creation of appropriate resources aimed at resisting co-optation, and the need to build collective cohesion and mechanisms to handle disagreements.
The unbearable lightness of being alternative: Idealism–realism and purism–pragmatism in Greek alternative media
Authors: Milioni Dimitra L. , Vatikiotis Pantelis
Published: June 2020

The article explores alternative media sustainability across a wide range of Greek projects. In this regard, it probes into a number of factors related to both the political economy (funding, organization) of these projects and the nature (real/‘imaginary’, broad reach/niche) of the relationship with their communities/audiences. The findings of the research reveal a dynamic and contradictory field regarding alternative media resilience in terms of the dialectical relationship of idealistic/realistic (on the production, organization level) and puristic/pragmatic (on the communication, reach level) features. The article concludes by highlighting the strategies employed by the most successful projects in terms of sustainability in relation to their positioning along the idealism/realism and purism/pragmatism nexus.
Community Radio’s Amplification of Communication for Social Change, Juliet Fox (2019)
Authors: Backhaus Bridget
Published: June 2020

Review of: Community Radio’s Amplification of Communication for Social Change, Juliet Fox (2019)

Palgrave Macmillan, 231 pp.,

ISBN 978-3-03017-315-9, h/bk, €72.79
Leicester School of Architecture Micro Living Unit Live Project 2019‐20
Authors: Jones Chris
Published: June 2020

Abstract Leicester School of Art final year students have been working with AEDES Aedes Network Campus (ANCB) in Berlin for three years. Since 1980, AEDEs Architecture Forum has been exhibiting and publishing internationally acclaimed and pioneering architecture alongside
its urban environment. AEDES was founded, as the product of a thoughts cess, to introduce contemporary architecture for public consideration. In August 2018, I discussed working within the area of housing particularly low-cost housing in Berlin, and more particularly as the State of Brandenburg
was investing in 100,000 new dwelling for low to medium income families. As part of this process we decided to imagine a micro living unit which we would investigate as the first project of the year for our students as part of a Technology module that proceeds the major design project in the
year. The unit could be based in Berlin or London.
Design thinking
Authors: Pieniazek Mik
Published: June 2020

Abstract A developing interdisciplinary dialogue (Design Think Space Group) across diverse dialects of academia, commercial enterprise, research practice and legislative governance has aggregated a common-heuristic that focuses on the domain of innovation for the Circular
Economy.
Longitudinal Renal Function in Liver Transplant Recipients With Acute-on-Chronic Liver Failure
Authors: Yazawa Masahiko , Maliakkal Benedict , Nair Satheesh , Podila Pradeep S. B. , Agbim Uchenna A. , Karri Saradasri , Khan Sabrina D. , Maluf Daniel , Eason James D. , Molnar Miklos Z. , Satapathy Sanjaya K.
Published: June 2020

INTRODUCTION:

To analyze the impact of acute-on-chronic liver failure (ACLF) immediately before liver transplantation (LT) on short-term kidney function.

METHODS:

In this retrospective study, we included 416 of 687 consecutive patients who had an estimated glomerular filtration rates (eGFRs) at 3-month post-LT. We compared the non-ACLF (N = 356), ACLF with eGFR ≥30 mL/min/1.73 m2 (A-HGFR, N = 32), and ACLF with eGFR <30 mL/min/1.73 m2 (A-LGFR, N = 28) groups at LT and for 2 kidney-related outcomes: (i) slope of eGFR by linear mixed model and (ii) time to development of composite kidney outcomes (eGFR < 15 mL/min/1.73 m2 or need for dialysis).

RESULTS:

The mean eGFRs at LT in non-ACLF, A-HGFR, and A-LGFR groups were significantly different as follows: 83.9 ± 29.5, 56.5 ± 31.2, and 21.6 ± 5.0 mL/min/1.73 m2, respectively. The eGFR slope significantly increased in A-LGFR group (+7.26 mL/min/1.73 m2/mo), whereas it remained stable in A-HGFR group (+1.05 mL/min/1.73 m2/mo) and significantly declined in non-ACLF group (−7.61 mL/min/1.73 m2/mo) by the first 3-month period. On the other hand, the eGFR slope in all groups stabilized after 3 months post-LT. A-LGFR group showed significantly increased risk of developing composite kidney outcomes in adjusted analysis (hazard ratio = 3.61, 95% confidence interval: 1.35–9.70) compared with the non-ACLF group. However, this significance disappeared after the further adjustment for eGFR at 3-month post-LT (hazard ratio = 1.91, 95% confidence interval: 0.70–5.23).

DISCUSSION:

The slopes of eGFR before 3-month post-LT were significantly different among non-ACLF, A-HGFR, and A-LGFR groups. The renal dysfunction in A-LGFR group stabilized after partial recovery by 3-month post-LT (eGFR reset point).
Trajectory Drift–Compensated Solution of a Stereo RGB-D Mapping System
Authors: Tang Shengjun , Zhu Qing , Li You , Chen Wu , Wu Bo , Guo Renzhong , Li Xiaoming , Wang Chisheng , Wang Weixi
Published: June 2020

Multiple sensors are commonly used for three-dimensional (3D)-mapping or robotic-vision applications, as they provide a larger field of view and sufficient observations to fulfill frame-registration and map-updating tasks. However, the data sequences generated by multiple sensors can
be inconsistent and contain significant time drift. In this paper, we describe the trajectory drift–compensated strategy that we designed to eliminate the influence of time drift between sensors, remove the inconsistency between the sequences from various sensors, and thereby generate
a coarse-to-fine procedure for robust camera-tracking based on two-dimensional–3D observations from stereo sensors. We present the mathematical analysis of the iterative optimizations for pose tracking in a stereo red, green, blue plus depth (RGB-D) camera. Finally, complex indoor
scenario experiments demonstrate the efficiency of the proposed stereo RGB-D simultaneous localization and mapping solution. The results verify that the proposed stereo RGB-D mapping solution effectively improves the accuracies of both camera-tracking and 3D reconstruction.
The Geometric Imaging Model for High-Resolution Optical Remote Sensing Satellites Considering Light Aberration and Atmospheric Refraction Errors
Authors: Wang Mi , Zhu Ying , Wang Yanli , Cheng Yufeng
Published: June 2020

With advances in satellite maneuvering imaging capability, stereoscopic images with large roll and pitch angles can be captured to improve the efficiency of observations. At the same time, the influences of light aberration and atmospheric refraction on image positioning accuracy will
be more significant. However, these errors are not accounted for in the traditional imaging and calibration model for optical agile satellites. In this study, the formation mechanisms of the aberration and atmospheric refraction errors in optical remote sensing satellite Earth observation
imaging were analyzed quantitatively, and correction models were constructed. From this, the traditional geometric imaging model was refined by introducing a correction model for aberration and atmospheric refraction errors to create a more comprehensive geometric imaging model. The feasibility
of an extended rational function model, based on the constructed more comprehensive geometric imaging model, was verified quantitatively.
Abuso sexual, de conciencia y de poder: hacia una nueva definición
Authors: Murillo José Andrés
Published: June 2020

El presente trabajo tiene como objetivo mostrar la evolución que ha tenido la definición de abuso sexual. Esta va desde una visión restringida e individual, centrada en la transgresión estrictamente genital, ejercida con fuerza, malinterpretando el fenómeno del abuso de poder en situaciones de vulnerabilidad, facilitando, así, el encubrimiento, la negación institucional y la retraumatización de las víctimas. La evolución va hacia una visión más integral, estructural y ética, que permita a la sociedad, personas e instituciones asumir su verdadera responsabilidad en el reconocimiento y la justicia con las víctimas. Esta es la única manera en que la sociedad y las organizaciones pueden cambiar de una cultura de abuso y encubrimiento a una cultura de atención y confianza lúcida.
Antibacterial Activity of Semi Purified Extract of Marine-Derived Trichoderma reesei PDSP 5.7 Using Bioguided Fractionation Method
Authors: Sibero Mada Triandala , Sitepu Nunung Febriany , Zhou Tao , Igarashi Yasuhiro
Published: June 2020

Bioguided fractionation method is commonly used to obtained targeted fraction with certain biological activity. In this study, bioguided fractionation method using HPLC was applied to obtained antibacterial fractions from marine-derived fungus Trichoderma reesei PDSP 5.7. The result shows that fraction from mycelium and medium extract had antibacterial activity against ESBL E. coli and S. enterica ser. Typhi with a range of inhibition zone was 1.35±0.15 to 8.82±0.22 mm2. From 32 fractions of each extract, the mycelial extract had 7 active fractions, 3 active fractions from broth medium which extracted using 1-butanol and 5 active fractions from ethyl acetate extract. This study indicated that crude extract of fungus T. reesei PDSP 5.7 was more potential as the source of antibacterial agents rather than the crude extract that obtained from its broth medium.
Massive scale-out of expensive continuous queries
Authors: Zeitler Erik , Risch Tore
Published: June 2020

Scalable execution of expensive continuous queries over massive data streams requires input streams to be split into parallel sub-streams. The query operators are continuously executed in parallel over these sub-streams. Stream splitting involves both partitioning and replication of incoming tuples, depending on how the continuous query is parallelized. We provide a stream splitting operator that enables such customized stream splitting. However, it is critical that the stream splitting itself keeps up with input streams of high volume. This is a problem when the stream splitting predicates have some costs. Therefore, to enable customized splitting of high-volume streams, we introduce a parallelized stream splitting operator, called parasplit. We investigate the performance of parasplit using a cost model and experimentally. Based on these results, a heuristic is devised to automatically parallelize the execution of parasplit. We show that the maximum stream rate of parasplit is network bound, and that the parallelization is energy efficient. Finally, the scalability of our approach is experimentally demonstrated on the Linear Road Benchmark, showing an order of magnitude higher stream processing rate over previously published results, allowing at least 512 expressways.
A HIF1a-Dependent Pro-Oxidant State Disrupts Synaptic Plasticity and Impairs Spatial Memory in Response to Intermittent Hypoxia
Authors: Arias-Cavieres Alejandra , Khuu Maggie A. , Nwakudu Chinwendu U. , Barnard Jasmine E. , Dalgin Gokhan , Garcia Alfredo J.
Published: June 2020

Sleep apnea causes cognitive deficits and is associated with several neurologic diseases. Intermittent hypoxia (IH) is recognized as a principal mediator of pathophysiology associated with sleep apnea, yet the basis by which IH contributes to impaired cognition remains poorly defined. Using a mouse model exposed to IH, this study examines how the transcription factor, hypoxia inducible factor 1a (HIF1a), contributes to disrupted synaptic physiology and spatial memory. In wild-type mice, impaired performance in the Barnes maze caused by IH coincided with a loss of NMDA receptor (NMDAr)-dependent long-term potentiation (LTP) in area CA1 and increased nuclear HIF1a within the hippocampus. IH-dependent HIF1a signaling caused a two-fold increase in expression of the reactive oxygen species (ROS) generating enzyme NADPH oxidase 4 (NOX4). These changes promoted a pro-oxidant state and the downregulation of GluN1 within the hippocampus. The IH-dependent effects were not present in either mice heterozygous forHif1a(HIF1a+/−) or wild-type mice treated with the antioxidant manganese (III) tetrakis(1-methyl-4-pyridyl) porphyrin (MnTMPyP). Our findings indicate that HIF1a-dependent changes in redox state are central to the mechanism by which IH disrupts hippocampal synaptic plasticity and impairs spatial memory. This mechanism may enhance the vulnerability for cognitive deficit and lower the threshold for neurologic diseases associated untreated sleep apnea.
Sex Differences in Biophysical Signatures across Molecularly Defined Medial Amygdala Neuronal Subpopulations
Authors: Matos Heidi Y. , Hernandez-Pineda David , Charpentier Claire M. , Rusk Allison , Corbin Joshua G. , Jones Kevin S.
Published: June 2020

The medial amygdala (MeA) is essential for processing innate social and non-social behaviors, such as territorial aggression and mating, which display in a sex-specific manner. While sex differences in cell numbers and neuronal morphology in the MeA are well established, if and how these differences extend to the biophysical level remain unknown. Our previous studies revealed that expression of the transcription factors, Dbx1 and Foxp2, during embryogenesis defines separate progenitor pools destined to generate different subclasses of MEA inhibitory output neurons. We have also previously shown thatDbx1-lineage andFoxp2-lineage neurons display different responses to innate olfactory cues and in a sex-specific manner. To examine whether these neurons also possess sex-specific biophysical signatures, we conducted a multidimensional analysis of the intrinsic electrophysiological profiles of these transcription factor defined neurons in the male and female MeA. We observed striking differences in the action potential (AP) spiking patterns across lineages, and across sex within each lineage, properties known to be modified by different voltage-gated ion channels. To identify the potential mechanism underlying the observed lineage-specific and sex-specific differences in spiking adaptation, we conducted a phase plot analysis to narrow down putative ion channel candidates. Of these candidates, we found a subset expressed in a lineage-biased and/or sex-biased manner. Thus, our results uncover neuronal subpopulation and sex differences in the biophysical signatures of developmentally defined MeA output neurons, providing a potential physiological substrate for how the male and female MeA may process social and non-social cues that trigger innate behavioral responses.
A Set of Diverse Genes Influence the Frequency of White-Opaque Switching in Candida albicans
Authors: Brenes Lucas R , Lohse Matthew B , Hartooni Nairi , Johnson Alexander D
Published: June 2020

The fungal species Candida albicans is both a member of the human microbiome and a fungal pathogen. C. albicans undergoes several different morphological transitions, including one called white-opaque switching. Here, cells reversibly switch between two states, “white” and “opaque,” and each state is heritable through many cell generations. Each cell type has a distinct cellular and colony morphology and they differ in many other properties including mating, nutritional specialization, and interactions with the innate immune system. Previous genetic screens to gain insight into white-opaque switching have focused on certain classes of genes (for example transcriptional regulators or chromatin modifying enzymes). In this paper, we examined 172 deletion mutants covering a broad range of cell functions. We identified 28 deletion mutants with at least a fivefold effect on switching frequencies; these cover a wide variety of functions ranging from membrane sensors to kinases to proteins of unknown function. In agreement with previous reports, we found that components of the pheromone signaling cascade affect white-to-opaque switching; however, our results suggest that the major effect of Cek1 on white-opaque switching occurs through the cell wall damage response pathway. Most of the genes we identified have not been previously implicated in white-opaque switching and serve as entry points to understand new aspects of this morphological transition.
Association of LEP- and CTSF-genotypes with levels of meat quality PSE, NOR and DFD in pigs of large white breed of Ukrainian selection
Authors: Bankovska I. , Oliinychenko Y. , Balatsky V. , Buslyk T. , Hryshchenko S. , Susol R.
Published: June 2020

Aim. To study the distribution of genotypes by polymorphisms of the leptin (LEP SNP g.3469 T > C, LEP SNP
g.2845 A > T) and cathepsin F (CTSF SNP g.22 C > G) genes according to the quality levels PSE, NOR and
DFD meat in Large White pig breed of Ukrainian selection and to fi nd associations of genetic markers with
the total indicator of meat quality. Methods. We studied meat samples (m. longissimus dorsi) from 102 pigs of
Ukrainian Large White breed, raised to the weight at slaughter of 120 ± 5 kg in the experimental farm “Stepne”
of the Poltava region, Ukraine. The ranking of muscle tissue was carried out according to the total indicator of
meat quality (TM). PCR-RFLP analysis was used for DNA typing. The associations between genetic markers
and TM were determined using ANOVA. Results. Genetic population analysis of Large White breed pigs of
Ukrainian selection by genetic markers LEP SNP g.3469 T > C, LEP SNP g.2845 A > T and СTSF SNP g.22
C > G was carried out. The informative value of LEP SNP g.2845 A > T and СTSF SNP g.22 C > G, according
to the calculated polymorphism information content, was optimal for associative studies (PIC = 0.311 and
0.373, respectively). The distribution of meat samples by quality levels PSE, NOR and DFD was performed.
Most of them had traits of moderately expressed (n = 22) and weakly expressed (n = 59) PSE defect (light,
soft, exudative meat). The calculated coeffi cients of Chuprov’s mutual conjugation between the genotypes for
the studied SNPs and meat quality levels showed a moderate relationship between the genotypes for LEP SNP
g.2845 A > T and CTSF SNP g.22 C > G and meat quality levels, К = 0.26 and 0.24, respectively. According
to the results of ANOVA, the differences were found between homozygous and heterozygous CTSF SNP g.22
C > G genotypes in terms of the total indicator of meat quality. Conclusions. The meat of heterozygous pigs
for CTSF SNP g.22 C > G (g.22GC) is characterized by a higher total indicator of meat quality (4.6) compared
to the meat of homozygous animals g.22GG (4.2, p ≤ 0.05) and g.22CC (3.9, p ≤ 0.01).
Efficacy and selectivity of pendimethalin for weed control in soybean (Glycine max (L.) Merr.), Gezirastate, Sudan
Authors: Zain Suhaip , Dafaallah Awadallah , Zaroug Mohamed
Published: June 2020

Objective. The aim of the present study was to evaluate the effi cacy and selectivity of the herbicide pendimethalin
on weed control in soybean at Gezira State, Sudan. Methods. A fi eld experiment was carried out at
Gezira Research Station Farm, Wad Medani, Sudan during summer season 2018/2019. The pendimethalin
(Pendimight 500 EC®) was applied at three doses as pre-emergence treatment. The doses were 1.339, 1.785
and 2.232 Kg a.i./ha. Weeded and un-wedded treatments were included for comparison. The treatments were
arranged in a randomized complete block designed with four replicates. Data were subjected to descriptive
analysis and analysis of variance procedure (P ≤ 0.05). Signifi cant means were separated using Duncan’s Multiple
Range test. Results. The results showed that all herbicide treatments were effective in weed control. They
signifi cantly reduced weed infestation compared to un-weeded control and signifi cantly promoted the yield
and various growth characters of soybean over un-weeded control treatment, except pendimethalin at the dose
of 2.232 Kg a.i./ha which only reduced the plant population by 7% due to a phytotoxicity effect on soybean
as compared to un-weeded control treatment. Application of pendimethalin at the dose 1.339 kg a.i./ha signifi
cantly controlled grasses and broad leaf weeds in soybean. It was also found superior in respect of various
growth and yield attributes. Highest seed yield (1562.5 kg /ha) was recorded under pendimethalin treatment at
a dose of 1.339 kg a.i./ha. Chemical analysis of soybean seeds showed that no residues of the tested herbicide
were detected. Conclusions. It is concluded that the tested pre-emergence herbicide pendimethalin at the dose
of 1.339 kg a.i./ha could be used effectively and safely in controlling weeds in soybean crop.
A Core Outcome Set for Neonatal Opioid Withdrawal Syndrome
Authors: Kelly Lauren E. , Shan Flora , MacVicar Sonya , Czaplinksi Emily , Moulsdale Wendy , Simpson Sarah , Allegaert Karel , Jansson Lauren M. , Offringa Martin
Published: June 2020

BACKGROUND:

As rates of neonatal opioid withdrawal are increasing, the need for research to evaluate new treatments is growing. Large heterogeneity exists in health outcomes reported in current literature. Our objective is to develop an evidence-informed and consensus-based core outcome set in neonatal opioid withdrawal syndrome (NOWS-COS) for use in studies and clinical practice.

METHODS:

An international multidisciplinary steering committee was established. A systematic review and a 3-round Delphi was performed with open-ended and score-based assessments of the importance of each outcome to inform clinical management of neonatal opioid withdrawal. Interviews were conducted with parents and/or caregivers on outcome importance. Finally, a consensus meeting with diverse stakeholders was held to review all data from all sources and establish a core set of outcomes with definitions.

RESULTS:

The NOWS-COS was informed by 47 published studies, 41 Delphi participants, and 6 parent interviews. There were 63 outcomes evaluated. Final core outcomes include (1) pharmacologic treatment, (2) total dose of opioid treatment, (3) duration of treatment, (4) adjuvant therapy, (5) feeding difficulties, (6) consolability, (7) time to adequate symptom control, (8) parent-infant bonding, (9) duration of time the neonate spent in the hospital, (10) breastfeeding, (11) weight gain at hospital discharge, (12) readmission to hospital for withdrawal, and (13) neurodevelopment.

CONCLUSIONS:

We developed an evidence-informed and consensus-based core outcome set. Implementation of this core outcome set will reduce heterogeneity between studies and facilitate evidence-based decision-making. Future research will disseminate all the findings and pilot test the validity of the NOWS-COS in additional countries and populations to increase generalizability and impact.
Empirical study of the meaning of work measurement scale
Authors: Navajas Rosemeire Colalillo , Cohen Eric David
Published: June 2020

The meaning of work is increasingly aimed at providing fulfillment, personal identity and pursuit of professional purpose through a convergence of individual values and the work environment. This chain of events leads to a direct effect in personal motivation and organizational productivity. Accordingly, this paper aims to analyze the conceptual framework of the meaning of work model using confirmatory factor analysis, starting from a locally developed measurement scale. An empirical test is applied to data collected through a survey with 200 participants employed by a company located in the State of São Paulo, Brazil. The statistical analysis reveals the existence of two main dimensions, the first referring to justice at work, and the second to wear and dehumanization. The research demonstrates the need to employ confirmatory methods in order to provide the necessary basis for measurement scale validation with respect to the extant theory. The evidence herein presented allows us to conclude that the IMST construct is still being developed; continuous efforts are needed in order to ensure that the scale is effective and valid – in particular, with regards to the interaction between the personal and the social dimensions related to the meaning of work.
Um estudo sobre o processo de desenvolvimento de produtos-serviços em uma empresa de afiação e recuperação de ferramentas de corte industrial
Authors: Rufini de Souza Lucas Moraes , Amaral Glaycon Rodrigo , De Melo Filho Leonel Del Rey
Published: June 2020

Este artigo apresenta uma metodologia de processo de desenvolvimento de novos produtos em uma empresa prestadora de serviço na área de afiação e recuperação de ferramentas de corte industrial, localizada em Minas Gerais. A metodologia visa facilitar o desenvolvimento de novos serviços, servindo como guia de referência para projetos futuros. A estrutura proposta foi baseada em um estudo de caso do processo de desenvolvimento de um serviço: a afiação de uma serra de 2000mm para uma grande empresa do setor siderúrgico. Com a análise do estudo de caso, reuniões com os gestores e comparando com a teoria, foi possível chegar a uma metodologia que atendesse as necessidades da empresa objeto deste estudo.
A Gestão do Conhecimento Holística: análise de aderência do modelo de Hanashiro
Authors: Corrêa Fábio , Batista Jonathas Antunes , Ferreira Eric de Paula
Published: June 2020

Este artigo tem por objetivo analisar a aderência do modelo proposto por Hanashiro à Gestão do Conhecimento holística, de modo a identificar se lacuna de um modelo de gerenciamento do conhecimento com essa envergadura foi suprida. Emprega-se como método a Análise de Conteúdo qualitativa para analisar o referido modelo e a quantificação percentíca para evidenciar o nível de adesão desse. O resultado exprime que o referido modelo adere-se parcialmente a Gestão do Conhecimento holística, evidenciando que a lacuna científica ainda não foi suprida. Desse modo, esta pesquisa contribuir para o fomento de novas pesquisas rumo ao desenvolvimento de modelos holísticos para a Gestão do Conhecimento, evidenciando as partes críticas a serem considerados nessas estruturas.
Asset management system (ISO 55001) and Total Productive Maintenance (TPM): a discussion of interfaces for maintenance management
Authors: Silva Renan Favarão da , Souza Gilberto Francisco Martha de
Published: June 2020

In the current globalized scenario, high productivity is a competitive factor for the survival and success of organizations. Ensuring the physical assets of the company is performing its functions while minimizing the occurrences of quality defects and breakdowns is a challenge in the maintenance management. Among the diffused approaches is Total Productive Maintenance (TPM) and, more recently, the asset management system (AMS) of the international standard series ISO 55000. The objective of this work, therefore, is to discuss the interfaces between the approaches in order to clarify the correlations and sufficiency of the TPM for an AMS. For this, a three-part methodology was structured: content review, correlation of the themes and discussion of interfaces. It was observed that TPM is a model for maintenance management and widely used in the manufacturing industries, while the AMS is a broader approach. Therefore, it was evidenced TPM can be an applicable management model to handle the maintenance requirements of ISO 55001, although it is not sufficient by itself. Thus, it is expected that this work will clarify the organizations on the non-exclusive nature of two themes.
Effect of spectral overlays on visual parameters and reading ability: an integrative review
Authors: Vilhena Douglas de Araújo , Guimarães Márcia Reis , Guimarães Ricardo Queiroz , Pinheiro Ângela Maria Vieira
Published: June 2020

ABSTRACT Purpose: to provide an integrative review of indexed articles published from 2009 to 2019 on the effect of spectral overlays on visual parameters and reading ability. Methods: keywords were used to search seven databases. Duplicate entries, reviews, literature reviews, editor's comments, and congress abstracts were excluded, as well as papers that were not relevant, based on their titles and abstracts. A total of 52 articles, which were read in full, were eligible at this stage. Of these, 12 articles, published in Portuguese or English from 2009 to 2019, were included. Results: all 12 articles included evaluated the effect of overlays on the reading rate. There was an improvement in different visual parameters (ocular accommodation and eye movement), facial recognition, and reading (reading rate, relative efficiency, and comprehension). The use of overlays reduced visual stress regardless of refractive, orthoptic or cognitive disorders. The associated conditions investigated were autism spectrum disorder, Tourette syndrome, stroke, deafness, dyslexia, and auditory temporal processing disorder. Conclusion: the effectiveness of overlays in improving reading quality is consistently demonstrated in the literature. The reviewed articles showed that the overlays’ effect is more expressive when the visual stress is associated with conditions that present sensory alterations and cortical hyperactivity.
Selection of tomato lines and populations for fruit shape and resistance to tomato leafminer
Authors: Resende Nathalia CV , Silva Alex Antonio da , Maluf Wilson Roberto , Resende Juliano Tadeu V de , Zeist Andre Ricardo , Gabriel André
Published: June 2020

ABSTRACT The market requirement regarding fruit type varies from region to region and it is necessary to produce cultivars with different patterns of fruit morphology. Therefore, the aim of this study was to select lines with resistance to tomato leafminer and different fruit shapes in order to meet the different market segments. Seventy-six lines and pre-selected populations were used for pest resistance together with four other susceptible controls (TOM-584, TOM-684, NC-123S, and Santa Clara) and two wild accessions (Solanum pennellii ‘LA 716’ and S. habrochaites var. glabratum ‘PI-127826’) considered resistant. The experiment consisted of tests of resistance to the tomato leafminer Tuta absoluta. The selection of lines was efficient, being obtained 33 lines or populations resistant to the tomato leafminer that comprise the market segments of the types of multilocular fruit, Santa Cruz, Saladette or Italian, as well as intermediate standards of fruits.
Effects of artificial light sources on growth and phytochemicals content in green oak lettuce
Authors: Etae Nursalmeeyah , Wamae Yarodah , Khummueng Weeraya , Utaipan Tanyarath , Ruangrak Eaknarin
Published: June 2020

ABSTRACT The artificial light source is one of the most important factors in a controlled environment for vegetable production. It could provide new opportunities to improve growth and increase phytochemicals content in vegetables. Therefore, this study focused on the effects of artificial light sources on growth and phytochemicals in green oak lettuce (Lactuca sativa). The plants were grown under growth chamber with three artificial light sources, namely bar-LED (the 1:1:1 ratio of blue 460 nm : red 630 nm : red 660 nm), bulb-LED (the 2:1:1 ratio of blue 460 nm : red 630 nm : red 660 nm), and fluorescent lamp (FL) (the wavelength range 380-700 nm) for 4 weeks. The quality of bar-LED light was better than either bulb-LED or FL, when assessed by the parameters of photosynthetically active radiation (PAR), photosynthetic photon flux density (PPFD, 400-700 nm), PPFD-B (blue, 400-500 nm), PPFD-R (red, 600-700 nm), the yield photon flux density (YPFD), and the color of red. However, shoot and root (fresh and dry mass), leaf area, leaf number, and shoot/root ratio did not significantly differ between plants grown under bar-LED and bulb-LED, but they were significantly higher than plants grown under FL. Bulb-LED and bar-LED induced larger dry mass of the plants than FL. The dry mass per mole of artificial lighting was highest in plants grown under bar-LED. On the other hand, the fresh mass per mole of artificial lighting was highest in plants grown under bulb-LED. As regards power consumption, bar-LED provided the lowest consumption with 44.4% energy saving over the FL. Total phenolic content, 2,2’-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) and 2,2-diphenylpicrylhydrazyl (DPPH) activities were highest in plants grown under bar-LED. FL lighting gave the least contents of chlorophyll a and chlorophyll a + b. However, chlorophyll b and carotenoid contents did not significantly differ among the treatments. Thus, the results suggested that bar-LED has the potential to improve energy saving, and both growth and phytochemicals content of green oak lettuce grown in a controlled environment of vegetable production.
Consulte o seu médico: hormônios e medicalização da sexualidade
Authors: Sampaio Juliana Vieira , Medrado Benedito , Menezes Jaileila Araujo
Published: June 2020

Resumo Este artigo apresenta parte dos resultados de uma pesquisa de doutorado, focalizando nossas análises nos agenciamentos produzidos pelos hormônios na sociedade contemporânea, especificamente em sua relação com o processo de medicalização da sexualidade. O estudo tem como corpus de análise 34 vídeos que abordam direta ou transversalmente o uso de hormônios. Esse material está disponibilizado via internet, em canais do YouTube de uma indústria farmacêutica multinacional de grande porte. Os vídeos são aqui concebidos como “documentos de domínio público”, expressão cunhada por Peter Spink, para se referir às práticas discursivas que promovem circulação de saber-poder e modos de viver em nossa sociedade. Nossas análises evidenciam que os hormônios têm se articulado com uma série de elementos, em uma complexa rede, produzindo modos de subjetivação e causando controvérsias. Na condição de artefatos biossociais, os hormônios podem ser utilizados para garantir direitos sexuais e reprodutivos, mas também, antagonicamente, servem para promover a medicalização compulsória da sexualidade.