bluuebunny/crossref_metadata_2025 huggingface dataset:
ІНСТРУМЕНТАЛІЗАЦІЯ ЯДЕРНОГО ПОТЕНЦІАЛУ ЯК ТЕХНОЛОГІЯ ЗОВНІШНЬОЇ ПОЛІТИКИ ПІВНІЧНОЇ КОРЕЇ
Authors: Yukhymenko Ihor Ihorovych
Published: August 2022

Дослідження присвячено розгляду інструменталізації ядерного потенціалу як засобу зовнішньої політики Північної Кореї. Методологічною призмою дослідження є технологічний підхід. Автор доводить, що інструменталізація ядерного потенціалу є однією із провідних технологій зовнішньої політики Північної Кореї, яка є ефективним багатовимірним засобом використання наявності ядерної зброї для реалізації національних інтересів цієї країни на міжнародній арені. Технологія інструменталізації ядерного потенціалу Північної Кореї має декілька цілей. У цілому, можна виділити три основні цілі технології інструменталізації ядерного потенціалу. Це безпека, дипломатія та політика. Північнокорейські лідери розглядають технологію інструменталізації ядерного потенціалу як центральний засіб досягнення безпекових завдань щодо Південної Кореї. Ядерна зброя розглядається як інструмент для примусу супротивників, а не лише для їх стримування. I навіть вона здатна допомогти об’єднати півострів силою, якщо це необхідно. Завдяки використанню технології інструменталізації ядерного потенціалу Північна Корея здійснює реалізацію своїх дипломатичних завдань, домагається прямих та гучних переговорів з великими державами. КНДР вже давно використовує ядерну дипломатію в своїх економічних інтересах. Північна Корея має глибоко вкорінену «дипломатію отримання данини», в якій вона використовує стратегію ядерного вимагання та загроз для отримання грошових, енергетичних та продовольчих трансфертів від інших країн. Здійснення технології інструменталізації ядерного потенціалу пов’язане з реалізацією національних цілей. Розгортання цієї технології включає три компоненти: 1) доктрина, 2) командування та контроль, 3) можливості. Можна виділити чотири альтернативні стратегії розгортання технології інструменталізації ядерного потенціалу, які реалізує Північна Корея. Перша – демонстративна стратегія. Вона спрямована насамперед на досягнення політичних, дипломатичних або економічних національних цілей. Друга стратегія – провокуюча. Вона призначена для використання примари ядерної війни для інтернаціоналізації локальної кризи або істотного підвищення глобальних ставок потенційного конфлікту, щоб «провокувати» дії третіх сторін. Третя стратегія – це стратегія гарантованої відплати. Вона спрямована на стримування висококласних, загрозливих режиму нападів та примусу. Четверта стратегія - стратегія ведення війни. Вона призначена для стримування загрозливих режиму нападів, а також для примусу та навіть поразки збройних сил противника шляхом загрози застосування ядерної зброї першими.
Zur Ökonomik von Spitzenleistungen im internationalen Sport
Authors: Baade Robert A. , Schmitz Uschi , Schwank Bernhard , Du Bois Cindy , Heyndels Bruno , Leitão João , Weinbach Andrew P. , Swart Kamilla , Bob Urmilla , Késenne Stefan , Yuen Belinda , Daumann Frank , Hofmeister Hannes , Matheson Victor A. , Paul Rodney
Published: August 2022

Sport – insbesondere der Hochleistungssport – ist ein Faszinosum, das als Plattform für gesellschaftliche Anliegen genutzt wird. Hierauf gründen die unterschiedlichen Interessen am aktiven und passiven Sport und das staatliche Interesse am Spitzensport. In den meisten Ländern ist der Spitzensport nationales Anliegen: So bilden Staaten in nationalen Trainingszentren ihre Athleten aus, unterstützen ihre Sportverbände bei internationalen Wettbewerben oder fördern Bewerbungen für Sportgroßveranstaltungen.

Die Beiträge dieses Bandes geben einen fundierten Einblick in die Organisation des Hochleistungssports und zeigen die unterschiedlichen Wege ausgewählter Staaten auf.
Sport und Sportgroßveranstaltungen in Europa – zwischen Zentralstaat und Regionen
Authors: Humphreys Brad , Soebbing Brian P. , Rebeggiani Luca , Frick Bernd , Fritsch Christoph , Flatau Jens , Trosien Gerhard , Knaack Hans-Peter , Dietl Helmut M. , Duschl Tobias , Schmidt Horst R. , Thöni Erich , Barth Michael , Breuer Christoph
Published: August 2022

Die Autonomie des Sports, die verfassungsrechtlich verbrieft ist, wird durch das Gemeinschaftsrecht der EU nicht konsequent respektiert. So wird beklagt, dass die notwendige Kooperation der Verbände im Sport nicht hinreichend berücksichtigt wird. Hier setzen die Referenten des 9. Internationalen Hamburger Symposiums „Sport und Ökonomie“ an, wenn sie rechtliche und ökonomische Fragen um Sportgroßveranstaltungen aufgreifen und Vorschläge zur Stellung des Sports im europäischen Rahmen diskutieren. Aufgezeigt wird , dass der sogenannte Sport ökonomisch geprägt wird, was noch keine angemessene Entsprechung auf europäischer Ebene gefunden hat. Das wird zum Beispiel bei Sportwetten und dem Glücksspielmonopol deutlich.

Der Band wird die durch das EU-Weißbuch Sport und die Entschließung des Bundestages zum Sport in Europa entstandene Debatte weiter beleben.
Archive zwischen Konflikt und Kooperation / Arkiver mellem konflikt og samarbejde
Authors: Carstensen Peter Harry , Christensen Carina , Kargaard Thomsen Hans , Bischoff Malte
Published: August 2022

Mit der vorliegenden Publikation würdigen das Landesarchiv Schleswig-Holstein und die dänischen Staatsarchive den 75. Jahrestag der Unterzeichnung des deutsch-dänischen Archivabkommens. Wie es in der deutsch-dänischen Archivzusammenarbeit bereits Tradition ist, geschieht dies auf Deutsch und auf Dänisch. Alle Texte der Publikation liegen deshalb in beiden Sprachen vor.

Der damalige Archivar Hans Kargaard Thomsen, Kopenhagen, hat in den 1990er Jahren einen ausführlichen Bericht unter der Überschrift „Arkivoverenskomsten med Tyskland 1933 og dens forhistorie“ („Das Archivabkommen mit Deutschland von 1933 und seine Vorgeschichte“) verfasst. Er bildet das Kernstück der Veröffentlichung. Darauf folgen Handreichungen zur Benutzung der Archivalien, die aufgrund des Abkommens zwischen Deutschland und Dänemark 1936 ausgetauscht wurden. Die Archivare Malte Bischoff, Landesarchiv Schleswig-Holstein, und Hans Schultz Hansen, Landsarkivet for Sønderjylland, sind die Autoren dieser Texte.

Im Anhang befindet sich das deutsch-dänische Archivabkommen im Wortlaut.
The tol-like receptor 2 polymorphism significance for the development of sensitization to house dust mites in children with atopic dermatitis
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Mozyrska O.V.
Published: August 2022

Atopic dermatitis is a chronic recurrent inflammatory skin disease that affects 5-20% of children. Airborne allergens derived from house dust mites can cause atopic dermatitis. TLR2 play an important role in the recognition of house dust mite allergens. Purpose - to investigate the prevalence of sensitization to house dust mites in children with atopic dermatitis and the role of TLR2 rs4696480 polymorphism in the development of sensitivity to house dust mites. Materials and methods. The study included 100 patients with atopic dermatitis. Genotyping of the polymorphism TLR2 rs4696480 was performed in the patient group using real-time PCR. Measurements of sIgE to dust mites were performed by Western blotting according to the manufacturer’s protocol (Simesta-Medivis, Ukraine-Germany). Results. Sensitization to house dust mites was found in 48% of children. Children with elevated levels of specific IgE to dust mites had a significantly higher SCORAD index than patients without sensitization (p<0.001). In the group of children sensitized to house dust mites, there were significantly higher levels of total IgE (p<0.001) and a longer course of the disease (p<0.05). There was no statistically significant difference in the distribution of genotypes depending on the presence of sensitization to dust mites (OR=1.250 (0.481-3.245) for AA and AT; OR=2.125 (0.715-6.315) for AA and TT). Conclusions. This study showed that the susceptibility to dust mites among children with atopic dermatitis is 48%. The presence of susceptibility to house dust mites affects the severity of the disease. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local ethics committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the author. Key words: TLR2, house dust mites, atopic dermatitis, children.
Recent and historical sedimentation and sediment characteristics of Ōhiwa Harbour, New Zealand
Authors: La Croix Andrew D.
Published: August 2022

The Bay of Plenty Regional Council is seeking to understand historical and recent sedimentation in Ōhiwa Harbour, a barrier-enclosed lagoon, to help establish sediment accumulation rates and water quality limits in accordance with the Resource Management Act (1991) and the NZ Freshwater Policy Statement. To provide sedimentation data that is independent of sediment plate data already being collected by the Council, and to supplement other historical data, a series of nine vibracores, nine box cores, and 73 surface sediment samples were collected from across Ōhiwa Harbour. Three key vibracores were analyzed for their radionuclide activity (²¹⁰Pb and ²²⁶Ra) in an attempt to determine their sediment accumulation rates. However, no rate could be established due to very low and irregular radionuclide activity through the cores. It is probable that the method did not work due to the combined effects of hydrodynamic mixing and bioturbation. Sedimentological analysis was undertaken on all nine vibracores and box cores, which indicated that the intertidal sediments consist of five distinctive depositional units: clast supported calci-gravel, ripple to cross bedded sand, bioturbated sand, laminated to rippled silt, and bioturbated silt. Recognition and interpretation of these units will be useful for future workers interested in reconstructing the evolution of sedimentation within the harbour. Grain size of core sediment and surficial sediment around the harbour was compared to historical surface sediment maps. They show clearly that Ōhiwa Harbour is becoming muddier through time, although in a non-linear and complex way with some parts of the harbour getting sandier. The perimeter of the harbour and the upper harbour are the main areas affected by a fining grain size trend. Loss-on-ignition (LOI) of sediment indicates that organic carbon is more concentrated in fine-grained sediment than coarser sediment across the harbour. No clear stratigraphic pattern of LOI could be established. However, surface sediments display larger LOI along the perimeter of the harbour where the proportion of mud is greater. Three recommendations are put forth based on the results of this study, as well as gaps in knowledge discovered during data collection and analysis. The first is that determining longer-term (decadesâ€“millennia) sediment accumulation rates may be achievable by carbondating the abundant shell material contained within cores. The second is that calculation of sediment compaction under its own weight ('autocompaction') may help determine the causes of sedimentation and erosion in the harbour. The third and final recommendation is for repeat surface sediment surveys to be undertaken regularly, at intervals no greater than every five years. These insights will together yield a more complete picture of past, present, and future sedimentation and its effects in Ōhiwa Harbour.
Left atrial strain as a predictor of atrial fibrillation in patients with asymptomatic severe aortic stenosis and preserved left ventricular systolic function
Authors: Chilingaryan A. L. , Tunyan L. G. , Adamyan K. G. , Tumasyan L. R. , Kzhdryan H. K. , Sisakyan J. G. , Asatryan A. A. , Zelveyan P. H.
Published: August 2022

Aim. To study the structural and functional left heart parameters in patients with severe aortic stenosis (AS) and preserved ejection fraction (EF) in order to determine the risk of atrial fibrillation (AF).

Material and methods. The study included 84 patients (men, 37; mean age, 68±8 years) with severe AS and EF >55%. All patients had sinus rhythm and were asymptomatic. Echocardiography was performed to assess longitudinal strain of the left ventricle (LVLS), right ventricle, left atrium (LALS) and the left atrial stiffness (LAS) using the speckle tracking method. Left ventricular mass index (LVMI) and maximum left atrium volume index (LAVI) were also determined. Patients were followed up for 1 year.

Results. AF was reported in 27 (32%) patients, of which 9 (33%) had asymptomatic AF episodes detected by 48-hour electrocardiography. Eighteen (67%) patients with AF felt palpitations. Patients with and without episodes of atrial fibrillation had non-significant differences in LVMI, LAVI, and LVLS. Patients with atrial fibrillation had a lower LALS and a higher LAS compared with patients without atrial fibrillation. Regression analysis revealed that LALS and LAS were independent predictors of AF.

Conclusion. AF develops in about one third of asymptomatic patients with severe AS and normal EF. The development of AF predisposes to the onset of AS symptoms in most patients. LALS and LAS were predictors of AF in these patients. Identification of patients at risk of AF will allow for earlier aortic valve replacement.
New protocol for diagnosing exercise-induced arrhythmias and conduction disturbances in early and preschool age children
Authors: Vasichkina E. S. , Alekseeva D. Yu. , Gorozhankina E. Yu. , Kresteleva A. S. , Kofeynikova O. A. , Pervunina T. M.
Published: August 2022

Aim. To develop a protocol for diagnosing exercise-induced arrhythmias and conduction disturbances in children aged 3-6 years without structural heart disease.

Material and methods. The study included 20 patients (11 boys) aged 58,7±2,12 months with ventricular arrhythmias (VA) and/or atrioventricular (AV) block according to single electrocardiographic (ECG) records and/or 24-hour ECG monitoring. All patients underwent a thorough clinical and paraclinical examination, including exercise stress testing using original and Bruce protocols. The termination criteria were the first of following events: achievement of the heart rate set by the study aim; the appearance and/or aggravation of potentially dangerous arrhythmias and conduction disorders (single premature ventricular contraction (PVCs) with increasing frequency, and/or early PVCs, and/or paired PVCs, and/ or ventricular tachycardia (VT), and/or AV block); registration of allorhythmia (bigeminy) within 10 seconds.

Results. The termination criteria using the original protocol were achieved in all patients (n=20, 100%) compared to the standard Bruce protocol (n=5, 25,0%), p<0,001. The number of steps passed was significantly higher using original protocol (5,0 [5,00-6,00]) than when using the standard protocol Bruce 2,0 [2,03,0], p<0,05. Exercise tolerance was significantly higher when using the original protocol than the standard Bruce protocol (p<0,05). The probability of reaching the termination criteria using the original protocol were 116 times greater than using the standard Bruce protocol (odds ratio, 116, 95% confidence interval: 5,932250, p=0,0017). VAs were registered in 20,0% (n=4) of patients using the original protocol, while AV blocks — in 20,0% (n=4). Among the five patients who achieved the termination criteria using the standard Bruce protocol, VAs were recorded in 10,0% (n=2) of patients, while AV blocks — in 5,00% (n=1).

Conclusion. The use of exercise test with an original protocol makes it possible to achieve the termination criteria, increases its information content and diagnostic significance. It makes it possible to determine the nature of VAs and AV conduction dosorders.
Electrocardiographic signs of impaired depolarization (fragmented QRS, early ventricular repolarization, etc.) as markers of left ventricular systolic dysfunction
Authors: Gordeeva M. S. , Serdiukova I. A. , Krasichkov A. S. , Parmon E. V.
Published: August 2022

Aim. To study the relationship between a decrease in left ventricular (LV) ejection fraction (EF) and conventional electrocardiographic (ECG) signs associated with myocardial structure changes (pathological Q wave, ventricular arrhythmias), and relatively novel and less studied (fragmented QRS (fQRS), early ventricular repolarization (EVR)) and to evaluate their significance for identifying patients with mildly-reduced EF (mrEF).

Material and methods. The study included 148 patients who were treated and examined at the Almazov National Medical Research Center. During the ECG analysis, fQRS, EVR, pathological Q wave, and ventricular arrhythmias (VAs) were assessed. Echocardiography data were analyzed. Statistical processing was carried out, including Fisher and chi-squared test, as well as correlation and ROC analysis.

Results. Depending on the EF level, patients were divided into three groups: group 1 — patients with reduced EF (rEF) (<40%); group 2 — patients with mrEF (40-49%); group 3 — patients with preserved EF (pEF) (>50%). In the 1st group (with rEF), fQRS was registered in 16 (51,6%) patients, in the 2nd (with mrEF) — in 13 (44,8%), in the 3rd (with EF >50%) — in 16 (18,2%). Pathological Q wave was detected in the 1st group (rEF) in 20 (65%) patients, in the 2nd (mrEF) — in 10 (35%); in the 3rd (pEF) — in 15 (18%) (p<0,001). ROC analysis found that fQRS is more important for identifying patients with mrEF. In the 1st group (rEF), EVR was registered in 2 (6,5%) patients, in the 2nd (pEF) — in 2 (6,9%), in the 3rd (EF>50%) — in 11 (12,5%); the differences were not significant (p=0,5). The relationship of EVR, the number of PVCs and the presence of ventricular tachycardia with EF was not revealed.

Conclusion. FQRS is significantly more often observed with a decrease in EF and may be a marker of an mildly-reduced EF. There were no significant correlations between EVR and EF. There was also no relationship between VAs and LV systolic dysfunction.
Evaluation of interventricular delay during cardiac resynchronization therapy in patients with quadripolar systems in long-term postoperative follow-up
Authors: Chumarnaya T. V. , Lyubimtseva T. A. , Lebedeva V. K. , Gasimova N. Z. , Lebedev D. S. , Solovieva O. E.
Published: August 2022

Aim. To assess the association between changes in interventricular delay (IVD) and response to cardiac resynchronization therapy (CRT) during 24-month postoperative period in patients with quadripolar left ventricular leads.

Material and methods. This retrospective non-randomized study included data from 48 patients with implanted CRT devices with quadripolar left ventricular (LV) leads, examined 3, 6, 12, 24 months after operation. CRT responders were considered patients with a decrease in end-systolic volume (ESV) by more than 10% compared with preoperative. To test the hypothesis about the rationale for choosing the maximum IVD when installing the LV lead, the group of patients was divided into two subgroups as follows: one with the maximum IVD (IVDmax, n=24), the other — without this condition (n=24).

Results. A correlation was found between changes in IVD and ESV, as well as ejection fraction (EF) in the period of 6, 12 and 24 months after implantation compared to baseline. In the subgroup with IVDmax, the shortening of IVD in the postoperative period is higher at each considered period compared to the second subgroup, and in general, there is a more pronounced decrease in IVD over 24 months. At the same time, 3, 6, 12 months after surgery, patients with IVDmax show a significantly greater decrease in ESV and, accordingly, a greater increase in EF. Prognostic models of CRT response in the long term after implantation were created. Significant predictors were the initial IVD, changes in IVD in the early postoperative period and IVDmax selection. At the same time, not a single factor, taken separately, made it possible to separate responders and non-responders.

Conclusion. A greater shortening of the IVD corresponds to a greater decrease in LV ESV and EDV, as well as a greater increase in EF in the long-term postoperative period. The choice of quadripolar LV lead in accordance with the maximum IVD is accompanied by a decrease in the proportion of non-responders, a more pronounced decrease in electrical ventricular dyssynchrony and an improvement in systolic function.
Índice de Requalificação da Infraestrutura Urbana: o viaduto central em Brasília
Authors: Galimi Stefano , Buzar Márcio Augusto Roma , Pantoja João da Costa
Published: August 2022

Resumo Memórias e o orgulho do passado relacionados a locais culturais, muitas vezes proporcionados pela própria infraestrutura urbana, são recursos para o desenvolvimento urbano e de identidade regional, que podem ser recriados, interpretados e re-funcionalizados para atender às gerações atuais e futuras. Para tanto, este trabalho utiliza um modelo de intervenção de retrofit urbano na área central de Brasília, representado pelo viaduto da Galeria dos Estados, principal artéria viária da capital. A metodologia adotada para a classificação da infraestrutura urbana segundo o Índice de Requalificação da Infraestrutura Urbana (IRU) considera um modelo multicritério baseado em três parâmetros: estrutural, ambiental e espacial. Os dados obtidos apontam para a viabilidade de implementação desses parâmetros na avaliação das infraestruturas existentes, conectores das cidades contemporâneas.
Urban Infrastructure Requalification Index: the central viaduct in Brasília
Authors: Galimi Stefano , Buzar Márcio Augusto Roma , Pantoja João da Costa
Published: August 2022

Abstract Memories and pride of the past related to cultural places, often provided by the urban infrastructure itself, are resources for urban development and regional identity, which can be recreated, interpreted and re-functionalized to suit current and future generations. This work uses an urban retrofit intervention model in the central area of Brasília, represented by the Galeria dos Estados viaduct, the capital's main arterial road. The methodology adopted for the classification of urban infrastructure according to the Urban Infrastructure Requalification Index (IRU) considers a multi-criteria model based on three parameters: structural, environmental and spatial. The data point to the feasibility of implementing these parameters in the assessment of existing infrastructure, connectors of contemporary cities.
The immediate and short-term degradation of the wood surface in a cement environment measured by AFM
Authors: Li Juan , Kasal Bohumil
Published: August 2022

This study aims to measure the pit torus and border to monitor the immediate and short-term degradation of wood surfaces after the concrete is cast and the cement hydration releases heat. The surface morphology and adhesion force curves were measured by atomic force microscopy during the treatments in saturated calcium hydroxide solutions ranging from 1 h to 27 days. The results showed that the pit torus and pit border showed different degradation processes. The adhesion force was sensitive to the type of the surface chemical components exposed during the degradation, while the surface modulus, deformation and jump-off force ratio were sensitive to the surface structural strength. The surface modulus of the pit torus degraded to 0.61–0.66 of the untreated original (95% CI) after 7-h treatments, and degraded almost completely after 48-h treatments. The surface modulus of the pit border degraded to 0.83–0.95 of the untreated original (CI) after 10 days and to 0.20–0.23 of the untreated original (95% CI) after 27 days of treatments. The treatment temperature 50 °C caused a 10-times faster degradation in the torus modulus compared to the temperature 20 °C.
1991-2021 YILLARI ARASINDA GERÇEKLEŞTİRİLEN KURUMSAL MANTIK ÇALIŞMALARININ BİBLİYOMETRİK VE BİLİMSEL HARİTALAMA TEKNİKLERİ İLE İNCELENMESİ
Authors: DUMAN Hazal , KOÇ Umut
Published: August 2022

Bu çalışmanın amacı, 1991-2021 yılları arasında kurumsal mantık yaklaşımına ilişkin bilimsel üretim dinamikleri ve temaların stratejik gelişiminin ele alınmasıdır. Bu amaç doğrultusunda yönetim ve organizasyon alanında en yüksek etki oranına sahip 15 dergi temel alınmış ve dahil etme kriterleri doğrultusunda 235 araştırma incelenmiştir. Analiz sürecinde bilimsel üretim dinamiklerinin ortaya çıkarılmasında VOSviewer yazılımı, temaların stratejik gelişim haritalarının oluşturulmasında ise SciMAT yazılım programından faydalanılmıştır. Bilimsel üretim dinamiklerine ilişkin bulgular incelendiğinde alanda en fazla yayın yapan ülke Amerika, en aktif dergi Organizational Studies ve alana katkısı en yüksek yazar Michael Lounsbury olarak belirlenmiştir. Kurumsal mantık kapsamında temaların tarihsel gelişimi üç periyotta (1991-2001; 2002-2012; 2013-2021) incelenmiştir. Analiz sonucunda ilk periyotta 7, ikinci periyotta 17 ve son periyotta ise 52 ana temanın alandaki çalışmalara yön verdiği tespit edilmiştir. Periyotlara göre tema sayısının artmasına karşın, temalar arası sürdürülebilirliğin düşük olduğu araştırma sonucu öne çıkan bir bulgudur. Bu kapsamda alanda 1991 yılından bu yana geçen 30 yıllık süreçte sadece “kurumsal değişim” temasının üç periyotta da önemini koruyan bir araştırma teması olduğu tespit edilmiştir. Analiz sonucunda elde edilen bu durum, kurumsal mantık perspektifinde yaşanan orta yaş krizine dayandırılırken, alandaki tematik dağınıklığın önüne geçmek için öneriler geliştirilmiştir.
Growth promoter based on soursop leaf in Hy Line Brown pullets: Production parameters and production costs
Authors: Timana-Sandoval Manuel Augusto , Buendía-Molina Marilyn Aurora , Adama-Rojas Enrique Raúl , Diaz-Quispe Pablo Cesar , Mendoza-Rodriguez Katherine Yenniffer
Published: August 2022

Over the years, the poultry industry has used various types of promoters toimprove production; however, the current trend is to eliminate the growth promoters that cause resistance in humans, for example, the antibiotics in the European Union, there is a need to look for natural alternatives that are beneficial for the body and do not have a negative impact on the human health. The objective of the present study was to evaluate the productive parameters, in pullets from one to 16 weeks of age, when using a growth promoter in the feed, made from soursop leaf ferment, as well as todetermine its influence on production costs. The study population consisted of 200 Hy Line Brown pullets. A Completely Randomized Design (DCA), a treatment and a control, were used. Production parameters were recorded: weekly weight, feed consumption and feed conversion, in addition to recording production costs. The results showed that between the treatment and the control there was no significant difference between the productive parameters. However, the production cost favored the growth promoter treatment (S/16.87) compared to the control (S/17.47), making its use possible in thenatural feeding of birds.
The use of cover crops with Vicia sativaand application of island guanoin the improving soil fertilityand yield of Chenopodium pallidicaule
Authors: Olivera-Tacora Ludwin Cristian , Salcedo-Mayta Selima Milagros , Canihua-Rojas Jorge , Quispe-Huincho Miriam Rocio , Cosme-De La Cruz Roberto Carlos
Published: August 2022

This research was carried out with the purpose of knowing the effect of the vegetal cover with vicia (Vicia sativa) and the application of guano from islands in the fertility of the soil, height and yield of the cañihua (Chenopodium pallidicaule). A Completely Random Block Design was installed with four treatments and three repetitions: T1 (Cañihua Variety Cupi Sin Vicia), T2 (Cañihua Variety Cupi + guano de isla), T3 (Cañihua Variety Cupi + Vicia), T4 (Cañihua Variety Cupi + island guano + Vicia). The chemical content of the soil and agronomic parameters such as plant and yield were evaluated after harvest. The results were processed by ANVA analysis and multiple comparison test with a significance level of 5%. It was found that treatments T4 and T3 significantly increased the amount of nitrogen, phosphorus, and organic matter, as well as height and yield. A significant positive correlation was found between the variables yield with nitrogen organic matter and plant height. In conclusion, the vegetal cover with vicia and the application of guano from islands influence the increase in soil fertility, and the yield of the cañihua crop.
Anthoceros agrestis Bonn (hornwort) transformation v02 v1
Authors: Frangedakis Eftychis
Published: August 2022

Anthoceros agrestis Bonn (hornwort) transformation v02
Kasson Lab DNA Extraction v1
Authors: Macias Angie
Published: August 2022

This is a routine protocol for extracting DNA from various fungi. This extraction method is suitable for follow-up molecular work such as PCR amplification.
Seed Dormancy Status of Tropical Weedy Rice Population in Malaysia
Authors: Zulrushdi Amalia Qistina , Rejab Nur Ardiyana , Mispan Muhamad Shakirin
Published: August 2022

Seed dormancy is a trait that promotes the survival of weedy rice (Oryza sativa L.) in the rice seed bank. Weedy rice displays different level of dormancy depending on several factors including genetic control. Determining seed dormancy status of weedy rice is crucial to understand adaptive mechanism of the weed in the rice agroecosystem especially in the tropic regions. To investigate the degree of seed dormancy of weedy rice, 66 weedy rice seed samples were collected from Selangor rice fields. The degree of seed dormancy was determined by standard germination test at 7, 14, 21, 42, 49, 56, 63, and 284 days after imbibition. The dormancy status of weedy rice after >200d in room temperature storage was compared. A total of 92.4% of weedy rice samples displayed a high degree of dormancy upon maturation. The germination rates of sampled weedy rice are divergent, indicating weedy rice in the tropical regions has variation in the degree of seed dormancy. The cumulative germination rate was gradually increased over time and reached total dormancy loss at 284 days after the initial imbibition. The germination rate of weedy rice after >280 days in dry storage displayed a bimodal distribution pattern, with 25.8% and 18.2% of sampled weedy rice showed a strong and weak seed dormancy, respectively. This study showed that weedy rice seeds in Malaysia displayed a high degree of seed dormancy and can retain their viability more than 200d once imbibed. This trait can enhance the survivability of weedy rice in the tropical rice agroecosystems.
Biosorption of Pb2+ using Fusarium sp. RS01, a Hg2+ and Pb2+-Resistant Indigenous Fungus of an Abandoned Illegal Gold Mining Site
Authors: Risa Nofiani Risa Nofiani , Rio Rio , Kiki Komalasari Kiki Komalasari , Puji Ardiningsih Puji Ardiningsih , Sri Juari Santosa Sri Juari Santosa
Published: August 2022

This study aims to identify and characterize Hg2+ and Pb2+-resistant indigenous fungi that originated in Mandor, an abandoned illegal gold mining site in West Kalimantan, Indonesia. The resistant fungus which has the highest ability in uptaking Pb2+ is then further examined for its biosorption characteristics towards Pb2+. Three different samples consisted of samples taken in the sand area (RP), rhizosphere area (RR) and sediment area (RS) were collected as the sources of fungi. The three types of samples were inoculated in a potato dextrose agar (PDA) medium supplemented with 7.4 ppm of HgCl2 and 7.5 ppm of PbCl2 for screening Hg2+ and Pb2+-resistant fungi, respectively. Each screened fungus was identified macroscopically and microscopically. The tolerant index (TI) towards Hg2+ and Pb2+ was checked by measuring the fungal growth diameter in a PDA medium without or with the presence of different HgCl2 or PbCl2 concentrations. From six identified fungi, five of them showed resistance towards Hg2+ and Pb2+ to maximum concentrations of 200 ppm of HgCl2 and 2085 ppm of PbCl2, respectively. The five identified fungi were Penicillium sp. RR01, Aspergillus sp. RR02, Aspergillus sp. RR03, Aspergillus niger RP01, and Fusarium sp. RS01. At the optimum condition of pH 6 and adsorption time 15 min, the application of 200 ppm of Fusarium sp. was able to remove 9.5 ppm of Pb2+. This Pb2+ biosorption followed well Freundlich isotherm model indicating that the Fusarium sp. RS01 had heterogenous active sites for the adsorption.
Effect of Different Methods of Deacidification on the Properties of Noni (Morinda citrifolia) Extract
Authors: Yap Yenny , Jamil Muhammad Afwan , Hashim Haslaniza , Maskat Mohamad Yusof
Published: August 2022

Deacidification of fruit extracts is necessary in certain situations which include consumer preference and product application. Although deacidification of noni extract using ion exchange resin and calcium carbonate addition has been reported, comparison between the two methods is lacking. This study was conducted to compare the effects of different deacidification treatments of ion exchange resin and calcium carbonate on the properties of noni extract. Ion exchange resin (Amberlite IRA-67) (R), calcium carbonate addition (CC), ion exchange resin followed by calcium carbonate addition (RC) and calcium carbonate addition followed by ion exchange resin (CR) were used to deacidify noni extract. Subsequently, analysis for pH, total soluble solids (TSS), total phenolic content (TPC), free radical scavenging ability (DPPH) and ferric reducing power (FRAP) were carried out. Compared to control, TPC, DPPH, and FRAP of noni extract decreased significantly (p<0.05) after deacidification using all different treatments. pH increased significantly (p<0.05) for all samples. TSS decreased significantly (p<0.05) after deacidification using all different treatments except for samples using resin (R) and calcium carbonate (CC). Deacidification using resin (R) produced a higher pH but lower TPC, DPPH and FRAP compared to calcium carbonate (CC). Ion exchange resin followed by calcium carbonate (RC) produced a lower (p<0.05) DPPH compared to calcium carbonate followed by ion exchange resin (CR). Deacidification of noni extract using calcium carbonate (CC) was the best method as it produced the smallest (p<0.05) reduction per change of pH for FRAP and no significant difference for DPPH compared to ion exchange resin (R).
Compton Scattering Study using Ludlum Configuration for Tissue-Equivalent Phantom Material Made from Soy-Lignin Bonded Rhizophora spp. Particleboard
Authors: Zuber Siti Hajar , Abdul Hadi Muhammad Fahmi Rizal , Oluwafemi Samson Damilola , Mohd Yusof Mohd Fahmi , Ab. Aziz Hashikin Nurul , Abdul Aziz Mohd Zahri , Hashim Rokiah , Mohd Isa Norriza
Published: August 2022

Rhizophora spp. particleboards were prepared at approximately (20.0 × 20.0 × 1.0) cm3 and at 1.0 g·cm-3 target density. The mass attenuation coefficient of the soy-lignin bonded Rhizophora spp. particleboard was measured by Compton scattering using Ludlum configuration utilizing the Cesium-137 (137Cs). Monte Carlo (MC) GATE code was employed to simulate the scattering by using the same set-up. Compton scattering results from both experimental and simulation methods were compared with XCOM value of water. Half value layer (HVL) and mean free path (MFP) were calculated and analyzed. For Compton scattering method in comparison to XCOM value of water, both non-coated and coated samples showed a statistically non-significant value with p-value more than 0.05. The overall results suggested that the mass attenuation coefficient, HVL and MFP of soy-lignin bonded Rhizophora spp. particleboard based on Compton scattering study is within close agreement with XCOM value for water, exhibiting its potential as phantom materials.
Statistical Optimization of Zinc Oxide Nanarod Synthesis for Photocatalytic Degradation of Methylene Blue
Authors: Mohd Raub Aini Ayunni , Yunas Jumril , Mohamed Mohd Ambri , Kazmi Jamal , Ridwan Jaenudin , Hamzah Azrul Azlan
Published: August 2022

In this work, synthesis process parameters of Zinc Oxide nanorods (ZnO NRs) photocatalyst is optimized using Taguchi Method to obtain the highest degradation rate of Methylene Blue dye, MB. The Taguchi L27 (38) orthogonal array technique was used to determine the optimum conditions for the synthesis of the nanostructured photocatalyst. Eight important synthesis process parameters were chosen in the analysis while the effects of the parameters were studied using signal-to-noise (S/N) ratio analysis using minitab-16. The ZnO NRs photocatalyst was synthesized via solution process route based on the parameters obtained from the layout of the orthogonal arrays. The optimized synthesized nanorods was then characterized using field emission scanning electron microscope (FESEM), X-ray diffraction (XRD), photoluminescence (PL), ultraviolet-visible near-infrared (UV-VIS-NIR), and Raman spectroscopies while the photodegradation of MB was determined by UV-VIS spectrum analysis under ultraviolet light irradiation. The results show that ZnO NRs with hexagonal wurtzite structure and bandgap energy of 3.25 eV have been obtained. The Taguchi analysis based on simulated experimental runs predicted the highest MB degradation percentage of 17.12% that can be achieved under optimum process conditions. Meanwhile, experimental photocatalytic degradation of MB using ZnO NRs synthesized under the same optimum condition achieved a degradation percentage of 17.27%, which deviates only 0.88% from the predicted value. This analysis could give an approach to optimize the synthesis process to ensure the good performance of nano-photocatalyst for the photodegradation of organic contaminations in industrial wastewater in a short time and cost-effective process.
HASAN IBN AL-SABBAH: LEADER OF A SECT OR PERSIAN GUERRILLAS?
Authors:   Taras Shevchenko National University of Kyiv, Pokhyl G.
Published: August 2022

The article examines the nature of the Nizarite movement in Iran in the early twelfth century, its background and the process of statehood. On the basis of analysis of available sources and literature the author has come to the conclusion that there is insufficient reason to consider this movement a national one. It cannot be described as such, even in partial form, as described by contemporary researcher Farhad Daftari. Although the role of Persian language and the struggle against the Seljuk Turk dynasty is significant, the movement is of a religious and political nature typical of the period and the region. The study used the historical-genetic method to examine the formation of the Nizarite movement under the leadership of al-Sabbah. The historical-typological method was necessary to highlight the key points in the movement which help to classify it into one type or another. The article will be useful for students and young scholars studying the Iranian Nizarites of the Alamut period.
FEATURES OF NORMATIVE ASSESSMENT OF WATER QUALITY OF WATER BODIES FOR RECREATIONAL PURPOSES IN UKRAINE
Authors:   Taras Shevchenko National University of Kyiv, Khilchevskyi V.K. , Zabokrytska M.R. ,   Lesya Ukrainka Volyn National University
Published: August 2022

The purpose of this study is to highlight modern approaches to the methods of normative assessment of water quality for recreational purposes in Ukraine. Water quality among a number of factors affecting the recreational use of a water body (geographic location, type of banks, availability of infrastructure, etc.) has the greatest dynamics. Its value under certain conditions can quickly outweigh all others. The analysis of publications shows that the studies of Ukrainian authors regarding the assessment of the water quality of water bodies for recreation purposes according to methodological approaches are divided into two directions – hygienic and ecological and geographical. It should be noted that hygienic is normative. Ecological-geographical approaches are important, but they are of a complementary nature. Regulatory methods, the use of which is a prerequisite for the development of projects for the use of surface water bodies of land for recreational water use or current assessments of the quality of their water, SSR 173-96 “State Sanitary Rules for Planning and Development of Settlements”. For sea waters, the “Rules for the protection of internal sea waters and the territorial sea of Ukraine from pollution and pollution” (2002) are applied. Monitoring of the laboratory service of the Ministry of Health of Ukraine on land-based water bodies showed that during the summer season of 2021 the overwhelming majority of samples taken in the places of organized beach recreation met the water quality standards: in terms of microbiological indicators – by 63.4-93.5%; by chemical indicators – by 52.5-91%. The main deviation in microbiological parameters in the samples is in the LPC index (lactose-positive E. coli). Monitoring of the medicinal products of the Ministry of Health of Ukraine on sea beaches showed that during the summer season of 2021 the overwhelming majority of seawater samples complied with quality standards: in terms of microbiological indicators – by 85.5-99.1%; by chemical indicators – by 84.9-100%. The main deviation in microbiological parameters in the samples is in the LPC index (lactose-positive E. coli). Seawater in the beach area in 2021 had a slightly higher quality than water in the beach area of land-based water bodies in terms of both microbiological and chemical indicators. There was also a slight tendency for water quality to deteriorate in the middle of the summer season (July), which is associated with an increase in air and water temperatures and an increase in the number of tourists.
Comprehensive bronchological examination in intensive diagnostics of patients with lung cancer
Authors: Musin M. F. , Bondarev A. V. , Repeikov A. V. , Faskhutdinova I. M.
Published: August 2022

The results of the application of aspiration biopsy under local anesthesia using a system of guided catheters in combination with bronchography in diagnostics are presented.lungs and in 75.4% - peripheral. Bronchographic changes were detected in all patients with central cancer and only in 14 out of 105 patients with peripheral cancer. Among 30 patients with decaying cancer, in 56.6% of cases it was possible to contrast the decay cavity. The proposed complex research method, applicable in outpatient settings, should be mandatory in the intensive diagnosis of lung diseases.
Intraoperative perfusion cholangiomanometry in assessing the functional state of the sphincter of Oddi
Authors: Kochnev O. S. , Sitdikov V. Z.
Published: August 2022

A new method of intraoperative diagnostics of the functional state of the sphincter of Oddi is proposed. The method is based on registration of sphincter irritations caused by hydrochloric acid solution. This allows you to differentiate reversible and irreversible changes in the terminal section of the common bile duct. 76 studies were conducted in patients with various pathologies of the major duodenal papilla. Based on the obtained sphincterograms, groups of patients were identified and the scope of surgical intervention was determined.
A method for the differential diagnosis of inflammatory and functional forms of lesions of the biliary system in children
Authors: Pikuza O. I. , Bulatov V. P. , Bzhasso Z. Kh.
Published: August 2022

A new method for the differential diagnosis of inflammatory and functional forms of lesions of the biliary system in children is described. This method is based on the reduction reaction of nitro blue tetrazolium (NBT-test). With cholecystitis, the values of the NBT test increase, with dysfunction, they are within the normal range.
Experience in the diagnosis and treatment of acute intestinal obstruction
Authors: Rosengarten M. Yu.
Published: August 2022

The results of treatment of acute intestinal obstruction in Tatarstan for 30 years were analyzed. A direct dependence of the outcomes of the operation on the timing of admission of patients to the hospital from the moment of the disease was revealed.
Pyrimidines in medical practice
Authors: Lazarev N. V. , Grekh I. F.
Published: August 2022

More than 20 years ago, one of us (N. V. Lazarev) came to the idea of the urgent need to find drugs whose main pharmacological property would be the ability to accelerate regeneration processes, especially reparative. The history of these searches and the thoughts underlying them have already been repeatedly covered in monographs and collections (N. V. Lazarev, 1950; books edited by N. V. Lazarev, 1951, 1960, etc.). This article presents in a very concise form, on the one hand, the results of studying the effects on the body of pyrimidine derivatives, which include the most effective stimulators of regenerative processes identified so far, and on the other, various therapeutic tasks, the resolution of which has become more feasible thanks to the use of pyrimidines.
Electro-pulse therapy of atrial fibrillation
Authors: Panchenko V. M. , Fokina A. M. , Schuplov I. V. , Kozhevnikova N. V. , Ashikhmina A. A.
Published: August 2022

Among the numerous cardiac arrhythmias, atrial fibrillation occupies a special place. Its significant prevalence, the possibility of serious hemodynamic disorders, the frequency of thromboembolic complications require the search for more effective therapeutic agents. Drug treatment of chronic atrial fibrillation with potassium chloride, novocainamide, cocarboxylase, digitalis and even quinidine is not always effective. In 1959 A. A. Vishnevsky, B. M. Zuckerman and S. I. Smelovsky applied a fundamentally new method of treating atrial fibrillation, based on the use of a powerful capacitor discharge. Rapidly accumulated clinical experience [1, 2, 4, 7, 8, 9, 10, 12 et al.] testifies to the high efficiency of the new method of treatment of atrial fibrillation. The sinus rhythm was restored in 80-90%. Most of the work on the use of electropulse therapy has been carried out in surgical clinics, and therefore its effectiveness in patients with atherosclerotic cardiosclerosis, myocardial infarction, thyrotoxicosis, etc. remains insufficiently studied.
About the electrolyte balance in heart failure
Authors: Movchan L. A.
Published: August 2022

Many works have been devoted to the study of the electrolyte composition of blood in circulatory insufficiency, but the data obtained are contradictory.
X-ray determination of the size and shape of the left atrium in patients with mitral heart disease
Authors: Melnichnov V. N.
Published: August 2022

Due to the widespread use of surgical treatment of mitral stenoses, the role and importance of X-ray diagnostics of mitral heart defects have increased. An important sign of mitral stenosis is an enlargement of the left atrium located directly above the narrowed opening. The heart changes its configuration due to an increase in the left atrium, right ventricle, its cone and bulging of the pulmonary artery arch. In a direct projection at high magnification, the left atrium forms a third arc along the left contour of the heart. Currently, it has been proven that the third arc on the left is formed not by the pulmonary cone, as previously thought, but by the ear of the left atrium [3, 6, 11, 12, 13]. The degree of bulging of the third arc characterizes the size of the left atrium. With a large arc, a large, well-accessible ear of the left atrium is noted during surgery, with a small arc a small ear. Significantly increasing, the left atrium in the form of an additional arc can also extend to the right contour of the heart [2, 3, 4, 8, 9].