bluuebunny/crossref_metadata_2025 huggingface dataset:
Keeping the Tradition Alive: Analysing the Work of C. De S. Kulatillake
Authors: Samarasinghe Kamani
Published: June 2023

The present review focuses on the vision, philosophy, and methodology of C. de S. Kulatillake’s exemplary
contribution to the subject. The methodology of this study is based on a qualitative approach narrative method,
and information was collected through interviews, records, autobiographies, and various reports and books
written by Kulatillake. Seven in-depth semistructured interviews were carried out at the University of the Visual
and Performing Arts, Colombo 07, Sri Lanka, in September and November 2022. The participants were senior
academic members and a scientific officer at C. de S. Kulatillake Research Centre. As a sampling method,
nonprobability purposive sampling was used. The data were evaluated using content analysis. Kulatillake has
always approached folk music from a scientific standpoint, linking it to ethnomusicology. He discovered 36
indigenous singing styles unique to Sri Lanka. According to Kulatillake, the Sri Lankan double-read instrument
horanewa is a West Asian migrant. The individuality of Sinhala drum music, its peculiar rhythms that do not
match the Indian “tal” systems, and Sinhala drum music is an incredibly remarkable performance style
incomplete sentence. He discovered that the strange aspect of the visama nadi (irregular pulse) movement in Sri
Lankan drum music is a unique style and should be accepted as a great feature inherited from the folk music of
this country. Kulatillake traced cultural identity and pride; documented, taught, and presented it to national and
international audiences; and preserved it for future generations, according to the study. A separate study focusing
on trailblazers who used music education as a safeguarding measure would be a worthwhile investigation that
would both enrich and broaden the findings of this study.
Review Essay of the 24th Symposium of the ICTM Study Group on Musical Instruments
Authors: Zhi Lin
Published: June 2023

This short review essay is dedicated to the 24th Symposium of the ICTM Study Group on Musical Instruments.
This symposium took place from March 29 to April 1, 2023. It was hosted by the Music Faculty of the University
of the Visual and Performing Arts, Colombo, in Sri Lanka.
ASSESSMENT OF THE IMPACT OF GROUNDWATER TABLE FLUCTUATIONS ON THE TRANSFORMATION OF SUBSURFACE CONTAMINATION WITH PETROLEUM PRODUCTS
Authors: Shpak O.M. , Havryliuk R.B. , Lohvynenko O.I. , Zapolskiy I.M.
Published: June 2023

This paper describes the actual problem of groundwater contamination with petroleum products and its transformation under the influence of climatic factors. The global experience of studying the influence of groundwater table fluctuations on the transformation of petroleum contamination, in particular, the processes of redistribution of mobile petroleum products, dissolution, evaporation, and biodegradation of hydrocarbon compounds, as well as the difference between the actual thickness of a mobile petroleum product layer in porous media and the apparent thickness of a mobile petroleum product layer in a monitoring well was analyzed, which is important to plan remedial actions.
The impact of groundwater table fluctuations on transformation of the petroleum contamination source within the warehouse of fuels and lubricants of the Boryspil airport was studied. As a result of groundwater table fluctuations, kerosene was “smeared” in the vadose zone, which led to an increase in the soil contamination area. During the observation period, a mobile kerosene layer almost disappeared when a groundwater table rose and restored when a groundwater table decreased, while the vadose zone was additionally contaminated since a new capillary zone was formed during each rise ofa groundwater table and kerosene. The long-term amplitude of groundwater table fluctuations was 2.4 m, and apetroleum contamination zone was also within these limits. During the observation period, the largest area of groundwater contamination with dissolved petroleum products was observed at the lowest groundwater table elevations in 2016. The highest concentration of dissolved hydrocarbons in groundwater (75.98 mg/dm3) wasfound within amobile kerosene lens. Beyond the mobile kerosene lens, spreading of groundwater contamination with dissolved hydrocarbons is limited.
The analysis of the monitoring data of the petroleum contamination source within the warehouse of fuels and lubricants of the Boryspil airport indicates that at present subsurface contamination with petroleum products is localized, and its further spreading is not expected. It is recommended to continue in the future monitoring of the natural attenuation of subsurface contamination.
Current approaches to quality assessment, non-clinical and clinical studies of dendritic cell vaccines in oncology
Authors: Nekhaeva T. L. , Kamaletdinova A. A. , Lutfullin M. F. , Tabanskaya T. V.
Published: June 2023

At present, personalised cellular immunotherapy is considered a promising approach to the treatment of malignant neoplasms. The effectiveness of these cellular immunotherapy methods is evaluated in the context of clinical and biological tumour characteristics and the state of the immune system of a particular patient. One of the immunotherapy options for cancer is the development of autologous dendritic cell vaccines.

The aim of this study was to analyse current methodological approaches to the evaluation of the quality, efficacy, and safety of dendritic cell cancer vaccines.

This review describes the functional role of dendritic cells in immune response regulation. The paper presents the results of literature analysis covering current approaches to obtaining dendritic cell vaccines with specific characteristics, quality assessment, studies of the anti-tumour efficacy of cell therapy products, and the experience of conducting non-clinical and clinical studies. The review highlights specific aspects of international experience in the registration and clinical use of cell therapy products. The authors discuss methodological approaches to non-clinical studies of dendritic cell vaccines, which should aim to obtain information to select the dose, route, and mode of administration and to identify immunological markers correlating to the clinical efficacy of cell therapy products. The paper covers international experience in conducting clinical trials of dendritic cell vaccines for various malignant neoplasms. The authors propose a list of quality attributes of human somatic cell-based medicinal products for further clinical use.
AB15 Ülkeleri ve Türkiye’de Vergi Gelirlerinin Gelir Vergilerinden Tüketim ve Servet Vergilerine Kaydırılmasının Ekonomik Büyüme Oranına Etkileri
Authors: ELÇİ Orhan , BAĞDADİOĞLU Necmiddin
Published: June 2023

Bu çalışmanın amacı Avrupa Komisyonu’nun AB15 ülkeleri için toplam vergi gelirleri değişmeden vergilerin dolaysız vergilerden dolaylı vergilere kaydırılmasının ekonomik büyümeyi uzun dönemde olumlu etkilediği önerisini genişleme sürecini temsilen Türkiye’yi de dâhil ederek test etmektir. Bu çerçevede 16 ülkenin 1970-2017 dönemi verileri kullanılarak havuzlanmış ortalama grup yöntemi ile elde edilen tahmin sonuçlarına göre gelir-nötr yaklaşım altında vergi gelirlerinin gelir vergilerinden tüketim vergilerine kaydırılması uzun dönemde ekonomik büyümeyi olumlu etkilemektedir. Ayrıca bu çalışmada vergilerin ilgili literatürde değinilmeyen kısa dönem etkileri de test edilmiştir. Vergilerin kısa dönemde ekonomik büyümeyi teorik beklentinin aksi yönünde etkileyebildiği sonucuna ulaşılmıştır. Bu sonucun arkasında yatan muhtemel nedenler kişisel gelir vergisi ile tüketim vergilerinde ülkelere göre uygulama farklılıkları ve kurumlar vergisinde küçük işletme sayısıdır.
Acknowledging the Dignity of Architectural Heritage Adding a Fourth Virtue to the Vitruvian Triad
Authors: Clarke Nicholas , Kuipers Marieke
Published: June 2023

Addressing the complex legacies of the past in architectural education and built constructions, calls for a reconsidering of the principles of architectural design and conservation. The current challenges of housing, sustainable development and heritage adaptation present huge dilemmas for architects. Yet today architects are only by exception trained to detect heritage values prior to drafting their interventions for adaptive reuse or upgrading. To this day, Western architectural thinking is influenced by the Vitruvian triad Firmitas, Utilitas and Venustas, and the truncated maxim ‘Form Follows Function’ as disseminated by the protagonists of the Modern Movement. These established a divide between the design for new-build and the care of already existing buildings. This divide is marked by the two Charters of Athens: the 1931 Carta del Restauro adopted at the First International Congress of Architects and Technicians of Historic Monuments, and La Chartre d’Athènes presented by Le Corbusier as a result of the 4th CIAM Congress on the Functional City (1933). This paper attempts to bridge the identified divide by adding the idea of ‘Dignitas’ (dignity) as an equal virtue to the Vitruvian triad. Though not new for itself, this concept may aid to raise awareness of architectural dignity in extant buildings. Keywords: architectural theory, architectural education, conservation theory, Renovation Challenge, Dignitas
Utilização de medicamentos que induzem osteoporose ou fratura em idosos com mieloma múltiplo: estudo transversal
Authors: ROSA Mariany Lara , DE PÁDUA Cristiane Menezes , MACHADO Taisa Lopes , DRUMMOND Paula Lana , SILVEIRA Lívia Pena , MALTA Jéssica Soares , REIS Adriano Max
Published: June 2023

Objetivo: descrever a frequência de utilização de medicamentos que induzem osteoporose ou fratura (MOF) em idosos com mieloma múltiplo (MM) e avaliar os fatores associados. Métodos: estudo transversal, desenvolvido com pacientes em tratamento de MM em três cenários: um hospital público de ensino, um serviço privado ambulatorial de onco-hematologia um hospital público, referência em oncologia. Os dados foram coletados entre abril de 2019 a março de 2020 por meio de entrevistas face a face e revisão de prontuários dos pacientes. A variável dependente foi o uso de MOF, que foram identificados em estudos previamente realizados a partir de duas bases de dados de farmacovigilância: Vigibase da Organização Mundial de Saúde e na Japanese Adverse Drug Event Report (JADER), que calcularam o reporting odds ratio (ROR) de osteoporose ou fratura para os medicamentos. Os medicamentos foram classificados segundo o nível 4 da sistemática da Anatomical Therapeutic Chemistry- ATC. Os fatores associados ao uso de MOF em pacientes com MM incluídos no estudo foram determinados por regressão logística múltipla. Resultados: foram incluídos 153 idosos (≥ 60 anos), com mediana de idade de 70,9 anos, predomínio do sexo feminino (54,2%). A maioria dos idosos (56,9%) foi atendida no serviço de saúde privado. A comorbidade mais encontrada foi hipertensão arterial (67,3%) seguida por diabetes mellitus (28,8%). Identificou- se que 73,2% dos idosos faziam uso de pelo menos um MOF. Os MOF mais frequentes foram os inibidores da bomba de prótons (IBPs) (29,2%), sulfonamidas (13,9%) seguidos por medicamentos relacionados a benzoadiazepinicos (11,9%) e outros opioides (10,4%). Os idosos que utilizaram MOF apresentaram as seguintes características: idade até 70 anos, sexo feminino, renda de até três salários, escolaridade alta (Ensino médio ou superior), multimorbidade, hipertensão arterial e polifarmácia. Na análise multivariada, obteve-se associação independente e positive entre uso de MOF e polifarmácia, MOF e escolaridade alta. Conclusão: a frequência de utilização de MOF pelos idosos estudados foi elevada e associada de forma positiva e independente com polifarmácia e alta escolaridade. As classes ATC dos MOF com maior frequência de utilização foram: IBP, diuréticos de alça (sulfonamidas), medicamentos relacionados a benzodiazepinicos e opioides.
Directrices para la materialización del derecho de la reparación integral en contextos plurales. Mención especial del caso boliviano
Authors: Pérez Arce Christian Nelio
Published: June 2023

Esta investigación realiza un estudio relacionado con el derecho a la reparación integral de las víctimas en contextos plurales, en particular en Bolivia. Es así que, tendrá como objetivo: plantear un conjunto de criterios para la materialización del derecho a la reparación integral en contextos plurales. Desde un punto de vista metodológico, es una investigación descriptiva, analítica y propositiva, que, en su construcción, realiza una revisión bibliográfica amplia, considerando documentos, datos y una serie de artículos publicados, y la jurisprudencia de la Corte Interamericana de Derechos Humanos. Sin embargo, se observa que existen avances normativos y jurisprudenciales en materia de reparaciones, que las víctimas directas e indirectas de contextos plurales no tienen garantizado el derecho a la reparación integral, al existir limitaciones fácticas en el marco normativo e institucional que materialice plenamente dicho derecho. El objetivo es trazar una serie de criterios que posibiliten de forma oportuna la materialización de los estándares del derecho a la reparación integral a víctimas de delitos, violaciones de derechos humanos, y otras cuestiones técnico-jurídicas, acordes a las particularidades presentes en contextos plurales.
The results of dysbiosis in the structure of periodontopathogens of the II order in patients with non-alcoholic fatty liver disease
Authors: Emelyanov D. V. , Emelyanova N. Y.
Published: June 2023

Objective — to identificate of the quantitative composition of some representatives of II order periodontopathogens in patients with NAFLD.
Materials and methods. 108 people were selected, including 44 patients with non‑alcoholic fatty liver disease (main group), 44 people — their spouses (comparison group). The control group consisted of 20 somatically healthy volunteers. A standard dental examination was performed using hygiene and periodontal indices, and some physical parameters of saliva (salivary salinity and viscosity, oral fluid endotoxin level in volume per unit time by enzyme‑linked immunosorbent assay) were determined. Quantitative composition of Fusobacterium nucleatum, Treponema denticola, Prevotela intermedia and Porphyromonas endodontalis in periodontal pockets was performed by real‑time PCR using paper endodontic absorbents. Statistical processing was performed using SPSS statistical programs using the nonparametric method.
Results. In NAFLD, negative changes in the physical parameters of saliva were observed (decreased salivary flow rate, increased viscosity, pH shift to the acidic side), increased levels of oral endotoxin and increased quantitative content of periodontal pathogens of the second order (increase in Porphyromonas endodontalis compared to the control group by more than 4.5 times and increase in Prevotela intermedia by 2.5 times). A positive correlation was found between the presence of halitosis and the quantitative content of Fusobacterium nucleatum (r=0.40; p=0.065) and the quantitative content of Porphyromonas endodontalis (r=0.36; p=0.022). We also found a negative correlation between the level of Fusobacterium nucleatum and salivary flow rate (r=– 0.51; p=0.000) and a positive correlation with saliva viscosity (r=0.49; p=0.001).
Conclusions. The combination of exogenous and endogenous risk factors forms a dysbiotic shift of conditionally pathogenic microflora (periodontal pathogens of the second order) in the oral cavity biotope, which creates conditions for the invasion of more aggressive microorganisms and the maintenance of chronic systemic inflammation. This fact requires increased attention from both the dentist and the internist, and the patient.
A clinical case of edematous syndrome: diagnostic search and treatment tactics of a complex patient in compliance with the internarial and domestic recommendations
Authors: Nikiforova Y. V. , Nesen A. O. , Myroshnychenko M. S.
Published: June 2023

Edematous syndrome is quite common in modern clinical practice. Swelling is one of the most common complaints that cause the patient to consult a doctor and often become the first clinical manifestation of many diseases. Fluid makes up approximately 3/5 of the human body weight, 70% of which is located in cells, and about 30% is extracellular. There is a constant exchange of electrolytes and other substances involved in metabolism between the cell and the extracellular fluid. Subcutaneous connective tissue under normal conditions contains a minimal amount of fluid. Edema fluid formed from blood plasma, which in pathological conditions under the influence of various factors is unable to retain water in the vascular bed, and water accumulates in excessive amounts in the tissues. Often, a patient refers to a doctor with the main complaint — the appearance of edema, and the correct interpretation of the origin of edema is important at this stage, because they are often a marker that reflects the severity and/or decompensation of the disease. Therefore, a detailed and comprehensive differential diagnosis of the edematous syndrome allows choosing the optimal tactics of the patient’s treatment.
The authors present a clinical case of diagnostic search and treatment tactics for edematous syndrome based on global and national recommendations. Patient V., 1983 year of birth, on May 8th, 2023, visited a nephrologist at the L. T. Mala National Therapy Institute. She believed that kidney disease caused swelling of her face and lower limbs. However, considering the long history of intestinal dysfunction, protein loss and edema, the case was revised as a manifestation of gastroenterological pathology. The patient was referred to a gastroenterologist. An extensive diagnostic search was conducted, which allowed not only to establish the correct diagnosis, but also to administer an effective therapy.
Anxiety-depressive disorders in patients with arterial hypertension who were in a combat zone
Authors: Koval S. M. , Rieznik L. A. , Starchenko T. G.
Published: June 2023

Objective — to study the frequency and severity of anxiety‑depressive disorders in patients with arterial hypertension (AH) who were in the war zone.
Materials and methods. Examinations involved 42 patients with AH of the II stage, 2—3 degree (20 men and 22 women), aged from 46 to 65 years (average age — (52.4±4.3 years), who were in the combat zone during the war in the city of Kharkiv and Kharkiv region of Ukraine. The degree and stage of hypertension were assessed in accordance with current recommendations. All subjects underwent general clinical laboratory and instrumental examination, as well as psychological testing using special questionnaires: Hospital Anxiety and Depression Scale — HADS, Hamilton Anxiety Scales (HAM‑A), Hamilton Depression Scales (HAM‑D), Spielberger‑Hanin Personality and Reactive Anxiety Scales, Posttraumatic Stress Disorder (PTSD) Screening Questionnaire (MH of Ukraine, 2016) and the Civilian Mississippi Scale for PTSD. Statistical analysis of the obtained data was carried out with standard methods using Microsoft Excel 7.0 and «SPSS 19.0» application programs.
Results. The anxiety and depressive disorders of varying severity, and PTSD symptoms have been established in the majority of AH patients, who were in the combat zone. The most frequent anxiety disorders were subclinical anxiety (according to HADS), anxiety symptoms and anxiety state (according to the (HAM‑A). Examinations with the use of Spielberger Personality and Reactive Anxiety Scale — Khanin showed an increased level of both personal and reactive anxiety, but the frequency of high‑level reactive anxiety was significantly higher than this indicator of personal anxiety. In the vast majority of examined patients with AH, subclinical depression (according to HADS) and mild or moderate depressive disorder (according to HAM‑D) have been established. In a third of the patients, depressive disorders were combined with anxiety disorders. Some of the patients with AH after being in the combat zone showed individual PTSD symptoms or developed clinical variant of PTSD (according to the Civilian Mississippi Scale for PTSD). Clinically expressed signs of anxiety and depression and PTSD symptoms were significantly more common in women than in men.
Conclusions. The negative impact of the presence of patients with hypertension in the combat zone on mental health indicators was established. In most of the examined patients, it was manifested as anxiety and depressive disorders of various degrees of severity, and PTSD symptoms. These violations require early diagnosis and timely adequate correction.
The effects of complex therapy with the additional dapagliflozin intake on the copeptin level in the blood serum of patients with diabetic nephropathy
Authors: Nesen A. O. , Semenovykh P. S. , Savicheva K. O. , Galchinska V. Y.
Published: June 2023

Objective — to determine the effects of drug therapy with inclusion of sodium‑glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin on the blood levels of copeptin as a biomarker of renal and vascular lesions in patients with diabetic nephropathy (DN) at various disease stages.
Materials and methods. Examinations involved 83 in‑hospital patients with DN, treated in the clinic of L. T. Mala National Institute of Therapy. Patients were divided into 2 groups depending on the therapy. 42 patients received a standard course of treatment, including antidiabetic drugs, renin‑angiotensin‑aldosterone system blockers and statins. In addition to standard therapy, the remaining 41 patients were administered SGLT2 inhibitor dapagliflozin in a dose of 10 mg per day. Patients were re‑examined after 6 months treatment. Determination of the copeptin level in blood serum was carried out by the enzyme immunoassay method using the set of reagents Human CPP Elisa Kit manufactured by FineTest, China.
Results. The results of investigation of the effects of complex nephroprotective therapy on the lipid profile indicators in patients with type 2 diabetes mellitus (DM2) demonstrated significant decrease in the levels of total cholesterol by 11.78% (р <0.05), triglycerides by 19.75% (р <0.05) and non‑significant increase of high‑density lipoproteins by 5.10%. In patients with DM2 and with glomerular filtration rate (GFR) >90 mL/(min · 1.73 m2) (I stage chronic kidney disease (CKD)) the level of copeptin after treatment decreased by 19.3% (p <0.05); in patients with (DM2) and GFR of 60—89 mL/(min · 1.73 m2) (CKD II stage) — by 18.9% (p <0.05), and with GFR of 45—59 mL/(min · 1.73 m2) (CKD III stage) — by 24.8% (p <0.05). The significant decrease of copeptin levels was revealed in diabetic patients with both preserved and reduced GFR. In DM2 patients with normal GFR, the copeptin level after standard treatment decreased by 17.6% (p <0.05), and in case of dapagliflozin administration by 20.6% (p <0.05). In patients with reduced GFR, blood serum copeptin levels decreased by 18.9% (p <0.05) after standard therapy, and by 22.1% (p <0.05) under the influence of dapagliflozin.
Conclusions. Complex therapy with the use of SGLT2 inhibitor dapagliflozin contributed to more significant reduction of copeptin levels in patients with DN compared to the standard treatment, regardless of the kidneys’ functional state. The decrease of copeptin levels against the background of the improved main clinical and laboratory parameters indicates not only an improvement in the kidneys’ functional state, but also reduction of cardiovascular risk in this group of patients.
TRIM35 is differentially expressed in metastasis to the brain in breast cancer.
Authors: Mamoor Shahan
Published: June 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that tripartite motif-containing 35, encoded by TRIM35, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. TRIM35 mRNA was present at decreased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of TRIM35 in primary tumors was correlated with patient distant metastasis-free and recurrence-free survival. Modulation of TRIM35 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Characteristic processes of human evolution caused the Anthropocene and may obstruct its global solutions
Authors: Waring Timothy , Wood Zachary T , Szathmary Eors
Published: June 2023

We propose that the global environmental crises of the Anthropocene are the outcome of a ratcheting process in long-term human evolution which has favored groups of increased size and greater environmental exploitation. To explore this hypothesis, we review the changes in the human ecological niche. Evidence indicates the growth of the human niche has been facilitated by group-level cultural traits for environmental control. Following this logic, sustaining the biosphere under intense human use will likely require global cultural traits, including legal and technical systems. We investigate the conditions for the evolution of global cultural traits. We estimate that our species does not exhibit adequate population structure to evolve these traits. Our analysis suggests that characteristic patterns of human group-level cultural evolution created the Anthropocene and will work against global collective solutions to the environmental challenges it poses. We illustrate the implications of this theory with alternative evolutionary paths for humanity. We conclude that our species must alter longstanding patterns of cultural evolution to avoid environmental disaster and escalating between-group competition. We propose an applied research and policy program with the goal of avoiding these outcomes.
The Influence of Bilingualism on Statistical Word Learning: A Registered Report
Authors: Simonetti Matilde Ellen , Lorenz Megan Galligan , Koch Iring , Roembke Tanja
Published: June 2023

While statistical word learning has been the focus of many studies on monolinguals, it has received little attention in bilinguals. The results of existing studies on statistical word learning in bilinguals are inconsistent, with some research reporting a bilingual advantage over monolinguals but others finding no difference between groups. Thus, our study will investigate statistical learning using the Cross-Situational Statistical Learning paradigm in two groups of English-German bilinguals (balanced and unbalanced) and English monolinguals. Participants will learn 1:1 mappings (one word maps onto one object) and 1:2 mappings (one word maps onto two objects). In contrast to previous studies, we will measure learning continuously and analyse trial-by-trial behaviour closely to understand fine-grained learning differences across language groups. We predict that it will generally be easier to acquire 1:1 than 1:2 mappings. More importantly, we predict that bilinguals will outperform monolinguals for 1:2 mappings only, consistent with a limited bilingual advantage.
Political and legal implications of defining “particularly vulnerable” for the Loss and Damage Fund
Authors: Sakshi  , Jackson Guy
Published: June 2023

At COP27, Parties agreed to establish a fund for loss and damage. During the COP28 opening plenary, the Loss and Damage Fund was operationalised. Despite this progress, significant questions about access to funding remain unanswered. Here, we engage with a key term in the decision texts—particularly vulnerable. How Parties frame and define the term ‘particularly vulnerable’ will influence funding allocation and devising eligibility or exclusion. We advance arguments against narrow, country-specific definitions of particularly vulnerable. To this end, we outline a brief history of the term particularly vulnerable and present insights from the existing climate fund allocations. We also engage with the emerging science of losses and damages, and critically unpack the implications of defining particularly vulnerable for loss and damage funding. We argue that it is possible to understand particularly vulnerable in a legally and politically just manner, while highlighting the limitations of excessive reliance or hopefulness around state actions, especially domestic remedies, in addressing vulnerability in specific communities. We recognise that the funds, as they have been pledged now, will not reach all vulnerable people. However, such limitation reinforces our argument that funding and support should be provided wherever vulnerability exists even if it increases liability of states.
Understanding Opioid Epidemic in US by US Food and Drug Administration Adverse Event reporting System Database
Authors: Milson Smith , Abraham Cole
Published: June 2023

Understanding Opioid Epidemic in US by US Food and Drug Administration Adverse Event reporting System Database
OpenStreetMap for Multi-Faceted Climate Risk Assessments
Authors: Mühlhofer Evelyn , Kropf Chahan , Bresch David , Koks Elco
Published: June 2023

Natural hazards pose significant risks to human lives, infrastructure, and ecosystems, necessitating a comprehensive understanding of climate risks for effective adaptation planning and risk management. However, climate risk assessments mostly focus on economic asset values and infrastructures such as roads and buildings, because publicly available data on more diverse exposures are scarce. The increasing availability of crowd-sourced geospatial data, notably from OpenStreetMap, opens up a novel means for assessing climate risk to a large range of physical assets. To this end, we present a stand-alone, lightweight, and highly flexible Python-based OpenStreetMap data extraction tool: OSM-flex. We demonstrate the potential and limitations of OpenStreetMap data for risk assessments by coupling OSM-flex to the open-source natural hazard risk assessment platform CLIMADA, and computing the current climate's winter storm risk and event impacts from the severe winter storm Lothar across Switzerland. Specifically, we evaluate the risks and impacts on forests, UNESCO heritage sites, railways, healthcare facilities, and airports, and compare them with traditional impact metrics such as asset damages and affected population. This study aims to provide researchers, practitioners, and decision-makers with insights into utilizing open-source data and software tools for conducting multi-faceted and high-resolution climate risk assessments.
Expanding the Toolbox: Machine-Based Item Desirability Ratings as an Alternative to Human-Based Ratings
Authors: Hommel Björn Erik
Published: June 2023

The accuracy of self-reported data in the social and behavioral sciences may be compromised by response biases such as socially desirable responding. Researchers and scale developers therefore obtain item desirability ratings, in order to maintain item neutrality, and parity with alternative options when creating forced-choice items. Gathering item desirability ratings from human judges can be time-consuming and costly, with no consistent guidelines with regard to required sample size and composition. However, recent advancements in natural language processing have yielded large language models (LLMs) with exceptional abilities to identify abstract semantic attributes in text. The presented research highlights the potential application of LLMs to estimate the desirability of items, as evidenced by the re-analysis of data from 14 distinct studies. Findings indicate a significant and strong correlation between human- and machine-rated item desirability of .80, across 521 items. Results furthermore showed that the proposed fine-tuning approach of LLMs results in predictions that explained 19 % more variance beyond that of sentiment analysis. These results demonstrate the feasibility of relying on machine-based item desirability ratings as a viable alternative to human-based ratings and contribute to the field of personality psychology by expanding the methodological toolbox available to researchers, scale developers, and practitioners.
Wenn das Klima am Hörsaal klopft: Eine neue Perspektive auf die psychologische Lehre anhand des Projekts 5-20-80
Authors: Asbrand Julia , Brakemeier Eva-Lotta , Reese Gerhard
Published: June 2023

Die menschengemachte Klimakrise wird als eine der größten globalenKrisen des 21. Jahrhunderts angesehen und hat bereits jetzt massive Auswirkungen auf die Umwelt und die Gesellschaft. Die Psychologie spielt eine wichtige Rolle bei der Erforschung der Ursachen, Auswirkungen und Lösungswege der Klimakrise im Rahmen von menschlichem Verhalten, Denkmustern und Emotionen. Die Psychologie hält Konzepte bereit, um Verhaltensänderung, Risikowahrnehmung, Kommunikation, emotionale Reaktionen, Gruppenprozesse, Zusammenarbeit und kollektive Handlung wie auch Politik und Entscheidungsfindung zu verstehen. Zudem wirkt die Klimakrise auf die psychische Gesundheit, indem beispielsweise Extremwetterereignisse Traumata auslösen, aber auch Ängste, Sorgen und depressive Verstimmungen hervorrufen. Schließlich eröffnet die Psychologie Lösungswege fürdie Klimakrise, indem sie aufzeigt, wie das Verhalten und die Einstellungen der Menschen beeinflusst und Kommunikationsprozesse verbessert werden können. Die Psychologie, die eine Schlüsselrolle bei der Bewältigung der Klimakrise spielt, sollte auchim Rahmen der universitären Lehre diese fokussieren. Wir schlagen in einem abgestuften Modell vor, 5%, 20% oder 80% der Lehre zu Themen wie Klimawahrnehmung, Umweltverhalten,Kommunikation über die Klimakrise und psychologische Bedeutung von Nachhaltigkeit anzubieten. Dieser Einbezug verfolgt die Ziele, bei den Studierenden das Bewusstsein für planetare Gesundheit zu schärfen, Handlungskompetenzen zu fördern und die nächste Generation von Studierenden für eine aktive und verantwortungsvolle Rolle in der Bewältigung der Klimakrise zu befähigen bzw. zu ermächtigen.
The Untrustworthy Evidence in Dishonesty Research
Authors: Bartoš František
Published: June 2023

Replicable and reliable research is essential for cumulative science and its applications in practice. This article examines the quality of research on dishonesty using a sample of 278 hand-coded test statistics from 99 articles. Z-curve analysis indicates a low expected replication rate, a high proportion of missing studies, and an inflated false discovery risk. Test of insufficient variance (TIVA) finds that 11/61 articles with multiple test statistics contain results that are `too-good-to-be-true'. Sensitivity analysis confirms the robustness of the findings. In conclusion, caution is advised when relying on or applying the existing literature on dishonesty.
The effect of context on the acquisition of two separate motor sequences: the potential downside of segmentation
Authors: Tal Amir , Ashkenazi Simone Schwizer , Finazzi Simona , Vakil Eli
Published: June 2023

Context plays a crucial role in episodic memory encoding retrieval. However, its influence on implicit motor learning is less clear. Here, we tested whether contextual information would facilitate acquisition of two overlapping sequences. Two groups underwent an ocular motor version of the serial reaction time task (SRTT) embedded with two interleaved sequences. In one group, a different display configuration was used for each sequence, while in the other group one display configuration was used for both. Context did not enhance performance as hypothesized, but rather impeded learning. Contextual shifts reduced attempts to anticipate upcoming targets, thus slowing down acquisition of the next sequence. Findings highlight that several layers of information are acquired during sequence learning. Whereas carryover of sequence knowledge can interfere with acquisition of a new sequence, carryover of more fundamental knowledge can be beneficial. Thus, contextual segmentation may impede learning in early stages, even if conveying useful information.
The Influence of Sleep on Subjective Well-Being: An Experience Sampling Study
Authors: Lenneis Anita , Das-Friebel Ahuti , Tang Nicole , Sanborn Adam N , Lemola Sakari , Singmann Henrik , Wolke Dieter , von Muhlenen Adrian , Realo Anu
Published: June 2023

Previous research has associated sleep with subjective well-being (SWB), but less is known about the underlying within-person processes. In the current study, we investigated how self-reported and actigraphy-measured sleep parameters (sleep onset latency, sleep duration, sleep satisfaction, social jetlag, and sleep efficiency) influence SWB (positive and negative affect, life satisfaction) at the within- and between-person level. Multilevel analyses of data from 112 university students who completed a two-week experience sampling study revealed that higher within-person sleep satisfaction was a significant predictor of all three components of next day’s SWB (ps < .005). Higher between-person sleep satisfaction was also related to higher levels of positive affect and life satisfaction (ps < .005) whereas shorter self-reported between-person sleep onset latency was associated with higher positive affect and life satisfaction, and lower negative affect (ps < .05). However, longer actigraphy-measured within-person sleep onset latency was associated with higher next day’s life satisfaction (p = .028). When including within- and between-person sleep parameters into the same models predicting SWB, only within-and between-person sleep satisfaction remained a significant predictor of all components of SWB. Additionally, we found an effect of higher self-reported within-person sleep onset latency on positive affect and of higher self-reported within-person sleep duration on life satisfaction (ps < .05). Our results indicate that the evaluative component of sleep—sleep satisfaction—is most consistently linked with SWB. Thus, sleep interventions that are successful in not only altering sleep patterns but also enhancing sleep satisfaction may stand a better chance at improving students’ SWB.
Meditation and Complexity: a Systematic Review
Authors: Atad Daniel Andrew , Mediano Pedro A. M. , Rosas Fernando , Berkovich-Ohana Aviva
Published: June 2023

Recent years have seen a growing interest in the use of measures inspired by complexity science for the study of consciousness. The work done in this field has shown remarkable results in discerning conscious from unconscious states, and in characterizing states of altered conscious experience following intake of psychedelic substances as involving enhanced complexity. However, the relationship between meditation and complexity is unclear, as empirical studies based on different theoretical frameworks point to meditation being associated with either enhancement or reduction of complexity. Here we provide a systematic review of the accumulating literature studying the complexity of neural activity in meditation, which disentangles different families of measures, short-term (state) from long-term (trait) effects, and meditation styles. Beyond families of measures used, our review uncovers a convergence toward identifying a higher complexity of neural activity during the meditative state when compared to waking rest or mind-wandering, and a decreased baseline complexity as a trait in experienced meditators compared to novices and controls. This review contributes to guide current debates and provides a framework for understanding the complexity of neural activity in meditation, while suggesting some practical guidelines for future research in the field.
The Geography of Military Occupation and its Effect on Palestinian Community Cohesion, Norms and Resistance Motivation
Authors: Penic Sandra , Vollhardt Johanna , Donnay Karsten , Albzour Mai , Bhavnani Ravi
Published: June 2023

In the context of military occupation, surveillance is a commonly used tactic to decrease resistance, effectively undermining an oppressed group’s sense of solidarity and cohesion. Our study examines how community cohesion - ties to local community - shapes the willingness to engage in nonviolent, civil resistance in the Occupied Palestinian Territories (OPT). We examine the psychological processes underpinning the link between community cohesion and civil resistance, and how these processes are affected by the geography of military occupation - the spatial system of Israeli settlements and surveillance infrastructure (checkpoints, the separation barrier, military installations). We address these questions by combining a representative survey of the adult population (N=1000) from 49 communities across the West Bank and Jerusalem with geo-coded data of settlements and the surveillance infrastructure. Our findings show that community cohesion predicts increased willingness to resist directly, and indirectly via perceived community norms of solidarity. Additionally, living in communities closer to settlements or the surveillance infrastructure predicts decreased community cohesion, lower expectations of solidarity with resistance, and less willingness to engage in resistance. Our findings contribute to the literature by demonstrating the role of community cohesion and norms in motivating resistance and depicting how these psychological processes are undermined by the structural conditions of control exercised by military occupation.
GORIC Evidence Aggregation: Combining Statistical Evidence for a Central Theory from Diverse Studies using an AIC-type Criterion
Authors: Kuiper Rebecca M. , Clapper Eli-Boaz
Published: June 2023

In social and behavioral science, the gold standard for scientific evidence is finding results that are consistent across independent studies. To summarize results from multiple studies, parameter estimates are conventionally aggregated with meta-analysis. However, this method is limited to studies that share the same context and design, which often means that a wealth of information remains unexploited. This paper proposes evidence aggregation using GORIC(A) weights: an alternative and/or complementary statistical tool for the aggregation of evidence across studies. Rather than aggregating parameter estimates to come to an overall estimate, GORIC(A) evidence aggregation combines support for a shared central theory and quantifies the overall support. It does so using GORIC(A), an information criterion that can evaluate both equality and inequality/order restrictions. GORIC(A) can be applied to a single study, and this GORIC(A) evidence can be aggregated over multiple studies, irrespective of context or design. The method is validated with a simulation study that shows that GORIC(A) evidence aggregation is not affected by study heterogeneity and can be used for evidence synthesis. This implies that GORIC(A) evidence aggregation can successfully combine evidence for a central theory over a widely diverse set of studies. This increases the available information to investigate a theory. Furthermore, GORIC(A) evidence aggregation aids in robustness and confidence of results because it can take into account the results of all type of studies that examine the central theory.
On Feynman's paradox
Authors: Torres del Castillo Gerardo Francisco
Published: June 2023

We review the Feynman paradox related to the conservation of the angular momentum in systems with an electromagnetic field. We show that the angular momentum is conserved if it is adequately defined.
Pantropic canine coronavirus induces canine M1 macrophage polarization in vitro
Authors: Vieira Flávia Volpato , Nalesso Rebeca Figueiredo , Panegossi Letícia Colin , Godoy Icaro Alex'Sanderson Pereira , Baptistella Jamila Cristina , Cardoso Tereza Cristina
Published: June 2023

Emerging coronavirus infections are a major threat to global public health. In this respect, a novel recombination of canine coronavirus (CCoV) and feline coronavirus (FCoV) was described among human biological samples, giving rise to a potential zoonosis. Despite all efforts, the host‒virus immune response related to CCoV is still unknown. In this study, pantropic CCoV infection of canine macrophages, derived from peripheral blood monocytes, was performed. After infection, macrophages were first polarized to the M1 and/or M2 phenotype. Moreover, infection kinetics, cell viability, apoptosis, mitochondrial dysfunction associated with reactive oxygen species and oxide nitric production were measured. Our results demonstrated that virus infection mainly polarized host macrophages to the classically activated (M1) phenotype, as demonstrated by amoeboid morphology with numerous fibrillary cytoplasmic processes followed by classical phenotypes. Viral infection released new particles 18 h post-infection associated with a decrease in viable cells. Furthermore, upon CCoV infection, M1 cells exhibited reduced phagocytosis properties, as evidenced by a neutral red uptake assay. This in vitro method opens an avenue for further studies on host-virus interaction.
Variação linguística, ensino e interfaces: resultados e propostas
Authors: Vieira Silvia Rodrigues , Rocha Jéssica Araújo Moraes da , Silva Lívia Ferreira Alves da , Lima Luiza de Carvalho de , Lima Monique Débora Alves de Oliveira
Published: June 2023

A relação entre variação linguística e ensino constitui, sem dúvida, um dos aspectos mais relevantes para o contexto pedagógico na Educação Básica. Neste livro, essa relação é explorada em diferentes temáticas e perspectivas: o estabelecimento da norma-padrão; o tratamento dos materiais didáticos; uso e avaliação de fenômenos variáveis; relatos de experiência e propostas pedagógicas; contexto plurilíngue e ensino de línguas estrangeiras/adicionais. Leitura essencial a professores e pesquisadores da área.
Emulsion Liquid Membrane for Pesticides Removal from Aqueous Solution: Emulsion Stability, Extraction Efficiency and Mass Transfer Studies
Authors: Jaber Noor Q. , Mohammed Ahmed. A. , Nasir Qazi
Published: June 2023

The current study investigated the stability and the extraction efficiency of emulsion liquid membrane (ELM) for Abamectin pesticide removal from aqueous solution. The stability was investigated in terms of droplet emulsion size distribution and emulsion breakage percent. The proposed ELM included a mixture of corn oil and kerosene (1:1) as a diluent, Span 80 (sorbitan monooleate) as a surfactant and hydrochloric acid (HCl) as a stripping agent without utilizing a carrier agent. Parameters such as homogenizer speed, surfactant concentration, emulsification time and internal to organic volume ratio (I/O) were evaluated. Results show that the lower droplet size of 0.9 µm and higher stable emulsion in terms of breakage percent of 1.12 % were formed at 5800 rpm of homogenizer speed, 4 v% of span 80 surfactant, 8 min of emulsification time and 1:1 (I/O) ratio while 86.4% of Abamectin pesticides were extracted under these conditions. Extraction kinetics and mass transfer study were also accomplished. The outcome of this study can be extended to the removal of other type of pesticides from water and wastewater.