bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and Description of a Composite Hydrogeologic Framework for Inclusion in a Geoenvironmental Assessment of Undiscovered Uranium Resources in Pliocene- to Pleistocene-Age Geologic Units of the Texas Coastal Plain
Authors: Teeple Andrew , Becher Kent , Walton-Day Katherine , Humberson Delbert , Gallegos Tanya
Published: March 2022

A previously completed mineral resources assessment of the Texas Coastal Plain indicated the potential for the future discovery of uranium resources. Geoenvironmental assessments that include the hydrogeologic framework can be used as a tool to understand the potential effects of mining operations. The hydrogeologic framework for this study focused on the composite hydrogeologic unit of the tract permissive for the occurrence of uranium consisting of the upper part of the Miocene-age Fleming Formation/Lagarto Clay, Pliocene-age Goliad and Pleistocene-age Willis Sands, Pleistocene-age Lissie and Beaumont Formations, and Holocene-age alluvial sediments (fluvial alluvium and eolian sand deposits). This composite hydrogeologic unit, which contains the Chicot and Evangeline aquifers of the Gulf Coast aquifer system, is intended for inclusion in a regional-scale geoenvironmental assessment of as yet undiscovered uranium resources. This article provides (1) a brief literature review describing the geologic and hydrogeologic settings, (2) the methodology used to develop a composite hydrogeologic framework, and (3) descriptions and maps of the land-surface altitude, composite hydrogeologic unit base and midpoint depth, water-level altitude, depth of water, unsaturated and saturated zone thickness, and transmissivity and hydraulic conductivity. A composite hydrogeologic unit, created by combining geologic and hydrogeologic data and maps for individual geologic and hydrogeologic units, is intended for use as a tool in a geoenvironmental assessment to evaluate potential contaminant migration through various avenues. Potential applications include using the hydrogeologic framework as an input into a geoenvironmental assessment to help estimate the potential for (1) runoff of contaminants into surface water, (2) infiltration of contaminants into the groundwater (aquifers), or (3) movement of contaminants from the mining area through wind, groundwater-flow, or streamflow in a given permissive tract. The procedures outlined in this paper also provide a method for developing hydrogeologic frameworks that can be applied in other areas where mining may occur.
Research Progress on Sound Absorption of Electrospun Fibrous Composite Materials
Authors: Li Xiuhong , Peng Yujie , He Youqi , Zhang Chupeng , Zhang Daode , Liu Yong
Published: March 2022

Noise is considered severe environmental pollutant that affects human health. Using sound absorption materials to reduce noise is a way to decrease the hazards of noise pollution. Micro/nanofibers have advantages in sound absorption due to their properties such as small diameter, large specific surface area, and high porosity. Electrospinning is a technology for producing micro/nanofibers, and this technology has attracted interest in the field of sound absorption. To broaden the applications of electrospun micro/nanofibers in acoustics, the present study of electrospun micro/nano fibrous materials for sound absorption is summarized. First, the factors affecting the micro/nanofibers’ sound absorption properties in the process of electrospinning are presented. Through changing the materials, process parameters, and duration of electrospinning, the properties, morphologies, and thicknesses of electrospun micro/nanofibers can be controlled. Hence, the sound absorption characteristics of electrospun micro/nanofibers will be affected. Second, the studies on porous sound absorbers, combined with electrospun micro/nanofibers, are introduced. Then, the studies of electrospun micro/nanofibers in resonant sound absorption are concluded. Finally, the shortcomings of electrospun micro/nano fibrous sound absorption materials are discussed, and the future research is forecasted.
Nonmetallic Active Sites on Nickel Phosphide in Oxygen Evolution Reaction
Authors: Zhang Pengfei , Qiu Hongmei , Li Huicong , He Jiangang , Xu Yingying , Wang Rongming
Published: March 2022

Efficient and durable catalysts are crucial for the oxygen evolution reaction (OER). The discovery of the high OER catalytic activity in Ni12P5 has attracted a great deal of attention recently. Herein, the microscopic mechanism of OER on the surface of Ni12P5 is studied using density functional theory calculations (DFT) and ab initio molecular dynamics simulation (AIMD). Our results demonstrate that the H2O molecule is preferentially adsorbed on the P atom instead of on the Ni atom, indicating that the nonmetallic P atom is the active site of the OER reaction. AIMD simulations show that the dissociation of H from the H2O molecule takes place in steps; the hydrogen bond changes from Oa-H⋯Ob to Oa⋯H-Ob, then the hydrogen bond breaks and an H+ is dissociated. In the OER reaction on nickel phosphides, the rate-determining step is the formation of the OOH group and the overpotential of Ni12P5 is the lowest, thus showing enhanced catalytic activity over other nickel phosphides. Moreover, we found that the charge of Ni and P sites has a linear relationship with the adsorption energy of OH and O, which can be utilized to optimize the OER catalyst.
Phosphorus-Doped Graphene Electrocatalysts for Oxygen Reduction Reaction
Authors: Zhan Xinxing , Tong Xin , Gu Manqi , Tian Juan , Gao Zijian , Ma Liying , Xie Yadian , Chen Zhangsen , Ranganathan Hariprasad , Zhang Gaixia , Sun Shuhui
Published: March 2022

Developing cheap and earth-abundant electrocatalysts with high activity and stability for oxygen reduction reactions (ORRs) is highly desired for the commercial implementation of fuel cells and metal-air batteries. Tremendous efforts have been made on doped-graphene catalysts. However, the progress of phosphorus-doped graphene (P-graphene) for ORRs has rarely been summarized until now. This review focuses on the recent development of P-graphene-based materials, including the various synthesis methods, ORR performance, and ORR mechanism. The applications of single phosphorus atom-doped graphene, phosphorus, nitrogen-codoped graphene (P, N-graphene), as well as phosphorus, multi-atoms codoped graphene (P, X-graphene) as catalysts, supporting materials, and coating materials for ORR are discussed thoroughly. Additionally, the current issues and perspectives for the development of P-graphene materials are proposed.
Current Status of Epitranscriptomic Marks Affecting lncRNA Structures and Functions
Authors: Miller Henry E. , Ilieva Mirolyuba , Bishop Alexander J. R. , Uchida Shizuka
Published: March 2022

Long non-coding RNAs (lncRNAs) belong to a class of non-protein-coding RNAs with their lengths longer than 200 nucleotides. Most of the mammalian genome is transcribed as RNA, yet only a small percent of the transcribed RNA corresponds to exons of protein-coding genes. Thus, the number of lncRNAs is predicted to be several times higher than that of protein-coding genes. Because of sheer number of lncRNAs, it is often difficult to elucidate the functions of all lncRNAs, especially those arising from their relationship to their binding partners, such as DNA, RNA, and proteins. Due to their binding to other macromolecules, it has become evident that the structures of lncRNAs influence their functions. In this regard, the recent development of epitranscriptomics (the field of study to investigate RNA modifications) has become important to further elucidate the structures and functions of lncRNAs. In this review, the current status of lncRNA structures and functions influenced by epitranscriptomic marks is discussed.
Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene
Authors: Emblem Åse , Knutsen Erik , Jørgensen Tor Erik , Fure Hilde , Johansen Steinar Daae , Brekke Ole-Lars , Mollnes Tom Eirik , Karlsen Bård Ove
Published: March 2022

Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat invading microorganisms. Understanding the expression of long non-coding RNAs containing Alu elements in inflammation is important for reconstructing cell fate trajectories leading to severe disease. We have assembled a pipeline for computation mining of new Alu-containing long non-coding RNAs by intersecting immune genes with known Alu coordinates in the human genome. By applying the pipeline to patient bulk RNA-seq data with sepsis, we found immune genes containing 48 Alu insertion as robust candidates for further study. Interestingly, 1 of the 48 candidates was located within the complement system receptor gene C5aR1 and holds promise as a target for RNA therapeutics.
Association of Maternal Longitudinal Hemoglobin with Small for Gestational Age during Pregnancy: A Prospective Cohort Study
Authors: Xu Shangzhi , Wang Weiming , Li Qian , Huang Li , Chen Xi , Zhang Xu , Wang Xiaoyi , Han Weizhen , Hu Xingwen , Yang Xuefeng , Hao Liping , Xiong Guoping , Yang Nianhong
Published: March 2022

Background: Few studies have investigated the association of maternal longitudinal hemoglobin (Hb) with small for gestational age during pregnancy. The current study examined the associations of maternal Hb concentrations and Hb changes throughout the middle and late stages of pregnancy with small for gestational age (SGA) in a large prospective cohort study. Methods: This was a prospective cohort study, which enrolled pregnant women at 8–16 weeks of gestation and followed up regularly. Maternal Hb concentrations were measured at the middle (14–27 weeks) and late (28–42 weeks) stages of pregnancy, and the Hb change from the middle to late stage of pregnancy was assessed. The Log-Poisson regression model was used to identify the association of maternal Hb with SGA, including the implications of Hb during specific pregnancy periods and Hb change across the middle to late stages of pregnancy. Of the total 3233 singleton live births, 208 (6.4%) were SGA. After adjusting for potential confounders, compared with Hb 110–119 g/L, Hb ≥ 130 g/L at late pregnancy was significantly associated with a higher risk of SGA (adjusted RR: 2.16; 95% CI: 1.49, 3.13). When Hb changes from the middle to late stages of pregnancy were classified by tertiles, the greatest change in the Hb group (<−6.0 g/L) was significantly associated with a lower risk of SGA (adjusted RR: 0.56; 95% CI: 0.37, 0.85) compared with the intermediate group (−6.0~1.9 g/L). In conclusion, for women at low risk of iron deficiency, both higher Hb concentrations in late pregnancy and less Hb reduction during pregnancy were associated with an increased risk of SGA.
Inadequate Vitamin C Intake and Intestinal Inflammation Are Associated with Multiple Micronutrient Deficiency in Young Children: Results from a Multi-Country Birth Cohort Study
Authors: Fahim Shah Mohammad , Alam Md Ashraful , Alam Jinat , Gazi Md Amran , Mahfuz Mustafa , Ahmed Tahmeed
Published: March 2022

Children living in resource-limited settings often suffer from multiple micronutrient deficiencies (MMD). However, there lacks evidence on the correlates of MMD in young children. We investigated the role of diets, water, sanitation and hygiene practice, enteric infections, and impaired gut health on MMD in children at 24 months of age using data from the multi-country MAL-ED birth cohort study. Co-existence of more than one micronutrient deficiency (e.g., anemia, iron, zinc, or retinol deficiency) was considered as MMD. We characterized intestinal inflammation by fecal concentrations of myeloperoxidase (MPO) and neopterin (NEO) measured in the non-diarrheal stool samples. Bayesian network analysis was applied to investigate the factors associated with MMD. A total of 1093 children were included in this analysis. Overall, 47.6% of the children had MMD, with the highest prevalence in Pakistan (90.1%) and lowest in Brazil (6.3%). MMD was inversely associated with the female sex [OR: 0.72, 95% CI: 0.54, 0.92]. A greater risk of MMD was associated with lower vitamin C intake [OR: 0.70, 95% CI: 0.48, 0.94] and increased fecal concentrations of MPO [OR: 1.31, 95% CI: 1.08, 1.51]. The study results imply the importance of effective strategies to ameliorate gut health and improve nutrient intake during the early years of life.
Dysmetabolism and Neurodegeneration: Trick or Treat?
Authors: Capucho Adriana , Chegão Ana , Martins Fátima , Vicente Miranda Hugo , Conde Sílvia
Published: March 2022

Accumulating evidence suggests the existence of a strong link between metabolic syndrome and neurodegeneration. Indeed, epidemiologic studies have described solid associations between metabolic syndrome and neurodegeneration, whereas animal models contributed for the clarification of the mechanistic underlying the complex relationships between these conditions, having the development of an insulin resistance state a pivotal role in this relationship. Herein, we review in a concise manner the association between metabolic syndrome and neurodegeneration. We start by providing concepts regarding the role of insulin and insulin signaling pathways as well as the pathophysiological mechanisms that are in the genesis of metabolic diseases. Then, we focus on the role of insulin in the brain, with special attention to its function in the regulation of brain glucose metabolism, feeding, and cognition. Moreover, we extensively report on the association between neurodegeneration and metabolic diseases, with a particular emphasis on the evidence observed in animal models of dysmetabolism induced by hypercaloric diets. We also debate on strategies to prevent and/or delay neurodegeneration through the normalization of whole-body glucose homeostasis, particularly via the modulation of the carotid bodies, organs known to be key in connecting the periphery with the brain.
Investigation of Direct and Retro Chromone-2-Carboxamides Based Analogs of Pseudomonas aeruginosa Quorum Sensing Signal as New Anti-Biofilm Agents
Authors: Trognon Jeanne , Vera Gonzalo , Rima Maya , Stigliani Jean-Luc , Amielet Laurent , El Hage Salomé , Lajoie Barbora , Roques Christine , El Garah Fatima
Published: March 2022

Biofilm formation is considered a major cause of therapeutic failure because bacteria in biofilms have higher protection against antimicrobials. Thus, biofilm-related infections are extremely challenging to treat and pose major concerns for public health, along with huge economic impacts. Pseudomonas aeruginosa, in particular, is a “critical priority” pathogen, responsible for severe infections, especially in cystic fibrosis patients because of its capacity to form resistant biofilms. Therefore, new therapeutic approaches are needed to complete the pipeline of molecules offering new targets and modes of action. Biofilm formation is mainly controlled by Quorum Sensing (QS), a communication system based on signaling molecules. In the present study, we employed a molecular docking approach (Autodock Vina) to assess two series of chromones-based compounds as possible ligands for PqsR, a LuxR-type receptor. Most compounds showed good predicted affinities for PqsR, higher than the PQS native ligand. Encouraged by these docking results, we synthesized a library of 34 direct and 25 retro chromone carboxamides using two optimized routes from 2-chromone carboxylic acid as starting material for both series. We evaluated the synthesized carboxamides for their ability to inhibit the biofilm formation of P. aeruginosa in vitro. Overall, results showed several chromone 2-carboxamides of the retro series are potent inhibitors of the formation of P. aeruginosa biofilms (16/25 compound with % inhibition ≥ 50% at 50 μM), without cytotoxicity on Vero cells (IC50 > 1.0 mM). The 2,4-dinitro-N-(4-oxo-4H-chromen-2-yl) benzamide (6n) was the most promising antibiofilm compound, with potential for hit to lead optimization.
Ag-Contained Superabsorbent Curdlan–Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model
Authors: Permyakova Elizaveta S. , Konopatsky Anton S. , Ershov Konstantin I. , Bakhareva Ksenia I. , Sitnikova Natalya A. , Shtansky Dmitry V. , Solovieva Anastasiya O. , Manakhov Anton M.
Published: March 2022

This study focused on the synthesis and characterization of pure curdlan–chitosan foams (CUR/CS), as well as foams containing Ag nanoparticles (CUR/CS/Ag), and their effect on the skin repair of diabetic mice (II type). The layer of antibacterial superabsorbent foam provides good oxygenation, prevents bacterial infection, and absorbs exudate, forming a soft gel (moist environment). These foams were prepared from a mixture of hydrolyzed curdlan and chitosan by lyophilization. To enhance the antibacterial properties, an AgNO3 solution was added to the curdlan/chitosan mixture during the polymerization and was then reduced by UV irradiation. The membranes were further investigated for their structure and composition using optical microscopy, scanning electron microscopy, energy-dispersive spectroscopy, FT-IR spectroscopy, and XPS analysis and modeling. In vivo tests demonstrated that CUR/CS/Ag significantly boosted the regeneration process compared with pure CUR/CS and the untreated control.
Associations between the C3orf20 rs12496846 Polymorphism and Both Postoperative Analgesia after Orthognathic and Abdominal Surgeries and C3orf20 Gene Expression in the Brain
Authors: Nishizawa Daisuke , Nagashima Makoto , Kasai Shinya , Hasegawa Junko , Nakayama Kyoko , Ebata Yuko , Fukuda Ken-ichi , Ichinohe Tatsuya , Hayashida Masakazu , Ikeda Kazutaka
Published: March 2022

Considerable individual differences are widely observed in the sensitivity to opioid analgesics. We focused on rs12496846, rs698705, and rs10052295 single-nucleotide polymorphisms (SNPs) in the C3orf20, SLC8A2, and CTNND2 gene regions that we previously identified as possibly associated with postoperative analgesia after orthognathic surgery. We investigated associations between these SNPs and postoperative analgesia in 112 patients who underwent major open abdominal surgery in hospitals and were treated with analgesics, including opioids, after surgery. Total genomic DNA was extracted from peripheral blood or oral mucosa samples for genotyping each SNP. Effects of these potent SNPs on gene expression in the brain were also investigated in samples that were provided by the Stanley Foundation Brain Bank. In the association studies, carriers of the G allele of the rs12496846 SNP in the C3orf20 gene region were significantly associated with greater 24 h postoperative analgesic requirements among the three SNPs that were investigated (p = 0.0015), which corroborated a previous study of orthognathic patients (p < 0.0001). In the gene expression analysis, carriers of the G allele of the rs12496846 SNP were significantly associated with lower mRNA expression of the C3orf20 gene (p < 0.0001). These results indicate that this SNP could serve as a marker that predicts analgesic requirements.
The Anti-Inflammatory Effect of Nanoarchaeosomes on Human Endothelial Cells
Authors: Charó Nancy , Jerez Horacio , Tatti Silvio , Romero Eder Lilia , Schattner Mirta
Published: March 2022

Archaebacterias are considered a unique source of novel biomaterials of interest for nanomedicine. In this perspective, the effects of nanoarchaeosomes (ARC), which are nanovesicles prepared from polar lipids extracted from the extreme halophilic Halorubrum tebenquinchense, on human umbilical vein endothelial cells (HUVEC) were investigated in physiological and under inflammatory static conditions. Upon incubation, ARC (170 nm mean size, −41 mV ζ) did not affect viability, cell proliferation, and expression of intercellular adhesion molecule-1 (ICAM-1) and E-selectin under basal conditions, but reduced expression of both molecules and secretion of IL-6 induced by lypopolysaccharide (LPS), Pam3CSK4 or Escherichia coli. Such effects were not observed with TNF-α or IL-1β stimulation. Interestingly, ARC significantly decreased basal levels of von Willebrand factor (vWF) and levels induced by all stimuli. None of these parameters was altered by liposomes of hydrogenated phosphatidylcholine and cholesterol of comparable size and concentration. Only ARC were endocytosed by HUVEC and reduced mRNA expression of ICAM-1 and vWF via NF-ĸB and ERK1/2 in LPS-stimulated cells. This is the first report of the anti-inflammatory effect of ARC on endothelial cells and our data suggest that its future use in vascular disease may hopefully be of particular interest.
Experimental Comparison of Primary and hiPS-Based In Vitro Blood–Brain Barrier Models for Pharmacological Research
Authors: Danz Karin , Höcherl Tara , Wien Sascha Lars , Wien Lena , von Briesen Hagen , Wagner Sylvia
Published: March 2022

In vitro model systems of the blood–brain barrier (BBB) play an essential role in pharmacological research, specifically during the development and preclinical evaluation of new drug candidates. Within the past decade, the trend in research and further development has moved away from models based on primary cells of animal origin towards differentiated models derived from human induced pluripotent stem cells (hiPSs). However, this logical progression towards human model systems from renewable cell sources opens up questions about the transferability of results generated in the primary cell models. In this study, we have evaluated both models with identical experimental parameters and achieved a directly comparable characterisation showing no significant differences in protein expression or permeability even though the achieved transendothelial electrical resistance (TEER) values showed significant differences. In the course of this investigation, we also determined a significant deviation of both model systems from the in vivo BBB circumstances, specifically concerning the presence or absence of serum proteins in the culture media. Thus, we have further evaluated both systems when confronted with an in vivo-like distribution of serum and found a notable improvement in the differential permeability of hydrophilic and lipophilic compounds in the hiPS-derived BBB model. We then transferred this model into a microfluidic setup while maintaining the differential serum distribution and evaluated the permeability coefficients, which showed good comparability with values in the literature. Therefore, we have developed a microfluidic hiPS-based BBB model with characteristics comparable to the established primary cell-based model.
Carbohydrates Used in Polymeric Systems for Drug Delivery: From Structures to Applications
Authors: Di Xiangjie , Liang Xiao , Shen Chao , Pei Yuwen , Wu Bin , He Zhiyao
Published: March 2022

Carbohydrates, one of the most important compounds in living organisms, perform numerous roles, including those associated with the extracellular matrix, energy-related compounds, and information. Of these, polymeric carbohydrates are a class of substance with a long history in drug delivery that have attracted more attention in recent years. Because polymeric carbohydrates have the advantages of nontoxicity, biocompatibility, and biodegradability, they can be used in drug targeting, sustained drug release, immune antigens and adjuvants. In this review, various carbohydrate-based or carbohydrate-modified drug delivery systems and their applications in disease therapy have been surveyed. Specifically, this review focuses on the fundamental understanding of carbohydrate-based drug delivery systems, strategies for application, and the evaluation of biological activity. Future perspectives, including opportunities and challenges in this field, are also discussed.
Observation of Neutron-Induced Absorption and Phase-Mismatch for Quasi-Phase-Matched Second Harmonic Generation in Congruent Lithium Niobate
Authors: Chiang An-Chung , Chao Jiunn-Hsing , Lin Shou-Tai , Lin Yuan-Yao
Published: March 2022

We report an experimental observation of radiation-induced optical absorption in undoped congruent lithium niobate (LiNbO3) crystals between the 190 nm and 3200 nm wavelength range. It was found that high-dose (up to 288 Gy) gamma rays did not significantly affect the optical absorption of LiNbO3 during that wavelength range. However, upon the order of 1016 cm−2 neutron irradiation, the change in the absorption coefficient was up to 0.6 cm−1 at a wavelength of 532 nm and remained after 13 days in the dark at room temperature. The nonlinear optical performance was characterized by conducting third-order quasi-phase-matched second harmonic generation in neutron-irradiated periodically-poled LiNbO3, showing that the phase-matching condition was altered, and the conversion efficiency was still comparable with a non-irradiated one.
RSM Modeling and Optimization of CO2 Separation from High CO2 Feed Concentration over Functionalized Membrane
Authors: Suhaimi Nadia Hartini , Yeong Yin Fong , Jusoh Norwahyu , Chew Thiam Leng , Bustam Mohammad Azmi , Mubashir Muhammad
Published: March 2022

The challenges in developing high CO2 gas fields are governed by several factors such as reservoir condition, feed gas composition, operational pressure and temperature, and selection of appropriate technologies for bulk CO2 separation. Thus, in this work, we report an optimization study on the separation of CO2 from CH4 at high CO2 feed concentration over a functionalized mixed matrix membrane using a statistical tool, response surface methodology (RSM) statistical coupled with central composite design (CCD). The functionalized mixed matrix membrane containing NH2-MIL-125 (Ti) and 6FDA-durene, fabricated in our previous study, was used to perform the separation performance under three operational parameters, namely, feed pressure, temperature, and CO2 feed concentration, ranging from 3.5–12.5 bar, 30.0–50.0 °C and 15–70 mol%, respectively. The CO2 permeability and CO2/CH4 separation factor obtained from the experimental work were varied from 293.2–794.4 Barrer and 5.3–13.0, respectively. In addition, the optimum operational parameters were found at a feed pressure of 12.5 bar, a temperature of 34.7 °C, and a CO2 feed concentration of 70 mol%, which yielded the highest CO2 permeability of 609.3 Barrer and a CO2/CH4 separation factor of 11.6. The average errors between the experimental data and data predicted by the model for CO2 permeability and CO2/CH4 separation factor were 5.1% and 3.3%, respectively, confirming the validity of the proposed model. Overall, the findings of this work provide insights into the future utilization of NH2-MIL-125 (Ti)/6FDA-based mixed matrix membranes in real natural gas purification applications.
Metallic Nanoparticle Integrated Ternary Polymer Blend of PVA/Starch/Glycerol: A Promising Antimicrobial Food Packaging Material
Authors: Francis Dali Vilma , Thaliyakattil Saurav , Cherian Lucy , Sood Neeru , Gokhale Trupti
Published: March 2022

Advances in food processing and food packaging play a major role in keeping food safe, increasing the shelf life, and maintaining the food supply chain. Good packaging materials that enable the safe travel of food are often non-degradable and tend to persist in the environment, thereby posing a hazard. One alternative is to synthesize biodegradable polymers with an antimicrobial property while maintaining their mechanical and thermal properties. In the present study, biodegradable composites of PVA–starch–glycerol (PSG) incorporated with CuO and ZnO nanoparticles (NPs) were prepared as PSG, PSG–Cu, PSG–Zn, and PSG–CuZn films. Scanning electron microscopy, energy dispersive x-ray analysis, and thermogravimetric analysis were performed to study and characterize these films. The water barrier properties of the films improved significantly as the hydrophobicity of the PSG–CuZn film increased by 32.9% while the water absorptivity and solubility decreased by 51.49% and 60% compared to the PSG film. The Young’s modulus of the films incorporated with CuO and ZnO nanoparticles was lower than that reported for PVA, suggesting that the film possessed higher flexibility. The thermogravimetric analysis demonstrated high thermal stability for films. Biosynthesized CuO and ZnO nanoparticles exhibited antifungal activity against vegetable and fruit spoilage fungi, and hence the fabricated polymers incorporated with nanoparticles were anticipated to demonstrate an antifungal activity. The nanoparticle incorporated films exhibited fungicidal and bactericidal activity, suggesting their role in extending the shelf life of packaged food. The result of ICP-OES studies demonstrated the steady release of ions from the polymer films, however, EDX analysis demonstrated no leaching of CuO and ZnO nanoparticles from the films, thus ruling out the possibility of nanoparticles entering the packaged food. The strawberries wrapped with the fabricated films incorporated with nanoparticles demonstrated improved shelf life and retained the nutritional quality of the fruit. Among the four films, PSG–CuZn was the most promising for food wrapping since it exhibited better water-resistance, antimicrobial, thermal, and mechanical properties.
Correction: Almutairi et al. Application of Chitosan/Alginate Nanocomposite Incorporated with Phycosynthesized Iron Nanoparticles for Efficient Remediation of Chromium. Polymers 2021, 13, 2481
Authors: Almutairi Fahad , El Rabey Haddad , Alalawy Adel , Salama Alzahraa , Tayel Ahmed , Mohammed Ghena , Aljohani Meshari , Keshk Ali , Abbas Nasser , Zayed Mohamed
Published: March 2022

The authors wish to make the following corrections to the published paper [...]
Mechanical Properties and Water Absorption Capacity of Hybrid GFRP Composites
Authors: Wan Badaruzzaman Wan Hamidon , Dabbagh Noaman Mohammed Ridha , Salleh Kushairi Mohd , Saharuddin Esri Nasrullah , Mat Radzi Nur Fashiha , Azham Mohd Amir Ashraff , Abdullah Sani Shahrul Faizi , Zakaria Sarani
Published: March 2022

Hybrid glass fibre reinforced polymer (GFRP) composites have been used for decades in various engineering applications. However, it has a drawback with its application in marine/flood environments due to a lack of water resistance and frail mechanical stability. Floods have been considered one of the most periodic hazards that could hit urban areas, due to climate change. The present paper aims to address this gap and to investigate the mechanical properties (tensile, compressive, and flexural strength) and water absorption capacity of hybrid GFRP composite comprising woven E-glass fabric and epoxy resin, various reinforcing materials (kenaf and coconut fibres), and various filler materials (fly ash, nano-silica, and calcium carbonate (CaCO3). The composites with 30 wt.% GFRP, 50 wt.% resin, 15 wt.% fly ash, 5 wt.% CaCO3, 10 wt.% GFRP, 60 wt.% resin, and 30 wt.% fly ash showed the lowest water absorption property of 0.45%. The results revealed that the GFRP composite reinforced kenaf fibres with nano-silica, fly ash, and CaCO3 improved the water absorption resistance. At the same time, GFRP reinforced the coconut fibres with fly ash, and kenaf fibres with CaCO3 showed no favourable impact on water absorption. The identification of a hybrid GFRP composite with various reinforcing materials and fillers would assist future developments with a more compatible, enhanced, and reliable water-resistant composite, specifically for structural applications in flood-prone areas.
Special Issue on “Advances in Plasma Diagnostics and Applications”
Authors: Chen Zhitong , Attri Pankaj , Wang Qiu
Published: March 2022

Plasma is the fourth state of matter, contrasted with the other states: solid, liquid, and gas [...]
Diffusion of Ethanol in Supercritical Carbon Dioxide—Investigation of scCO2-Cosolvent Mixtures Used in Pharmaceutical Applications
Authors: Santos Cecília I. A. V. , Barros Marisa C. F. , Ribeiro Ana C. F.
Published: March 2022

Diffusion coefficients, D, for ethanol in supercritical carbon dioxide (scCO2) were measured in the temperature range 306.15–331.15 K and along the 10.5 MPa isobar, using the Taylor dispersion technique. The obtained diffusivities ranged from 1.49 × 10−8 to 2.98 × 10−8 m2 s−1, an order of magnitude higher than in usual liquids. The dependence of D on temperature and solvent density was examined. Various correlation models based in the hydrodynamic theory were assessed to estimate the diffusion coefficients, with reasonable results obtained for the Wilke–Chang and Lai–Tan models.
Holistic Process Models: A Bayesian Predictive Ensemble Method for Single and Coupled Unit Operation Models
Authors: Montano Herrera Liliana , Eilert Tobias , Ho I-Ting , Matysik Milena , Laussegger Michael , Guderlei Ralph , Schrantz Bernhard , Jung Alexander , Bluhmki Erich , Smiatek Jens
Published: March 2022

The coupling of individual models in terms of end-to-end calculations for unit operations in manufacturing processes is a challenging task. We present a probability distribution-based approach for the combined outcomes of parametric and non-parametric models. With this so-called Bayesian predictive ensemble, the statistical moments such as mean value and standard deviation can be accurately computed without any further approximation. It is shown that the ensemble of different model predictions leads to an uninformed prior distribution, which can be transformed into a predictive posterior distribution using Bayesian inference and numerical Markov Chain Monte Carlo calculations. We demonstrate the advantages of our method using several numerical examples. Our approach is not restricted to certain unit operations, and can also be used for the more robust interpretation and assessment of model predictions in general.
UAVs for Science in Antarctica
Authors: Pina Pedro , Vieira Gonçalo
Published: March 2022

Remote sensing is a very powerful tool that has been used to identify, map and monitor Antarctic features and processes for nearly one century. Satellite remote sensing plays the main role for about the last five decades, as it is the only way to provide multitemporal views at continental scale. But the emergence of small consumer-grade unoccupied aerial vehicles (UAVs) over the past two decades has paved the way for data in unprecedented detail. This has been also verified by an increasing noticeable interest in Antarctica by the incorporation of UAVs in the field activities in diversified research topics. This paper presents a comprehensive review about the use of UAVs in scientific activities in Antarctica. It is based on the analysis of 190 scientific publications published in peer-reviewed journals and proceedings of conferences which are organised into six main application topics: Terrestrial, Ice and Snow, Fauna, Technology, Atmosphere and Others. The analysis encompasses a detailed overview of the activities, identifying advantages and difficulties, also evaluating future possibilities and challenges for expanding the use of UAV in the field activities. The relevance of using UAVs to support numerous and diverse scientific activities in Antarctica becomes very clear after analysing this set of scientific publications, as it is revolutionising the remote acquisition of new data with much higher detail, from inaccessible or difficult to access regions, in faster and cheaper ways. Many of the advances can be seen in the terrestrial areas (detailed 3D mapping; vegetation mapping, discrimination and health assessment; periglacial forms characterisation), ice and snow (more detailed topography, depth and features of ice-sheets, glaciers and sea-ice), fauna (counting penguins, seals and flying birds and detailed morphometrics) and in atmosphere studies (more detailed meteorological measurements and air-surface couplings). This review has also shown that despite the low environmental impact of UAV-based surveys, the increasing number of applications and use, may lead to impacts in the most sensitive Antarctic ecosystems. Hence, we call for an internationally coordinated effort to for planning and sharing UAV data in Antarctica, which would reduce environmental impacts, while extending research outcomes.
Effects of the Time Sampling Interval on the Angular Combination Characteristics of Moon-Based Earth Observations
Authors: Deng Yu , Guo Huadong , Liu Guang , Huang Jing , Wang Hairong , Zhou Mengxiong , Ye Hanlin
Published: March 2022

Observation angles are of great importance with respect to Earth observation platforms. The richness of angular combination, i.e., the combination of three observational angles (viewing zenith angle, solar zenith angle, and relative azimuth angle), is an important parameter to illustrate the angle sampling capability of an Earth observation platform. Here, the angular combination characteristics of a Moon-based platform were investigated and compared with existing artificial satellites. Furthermore, the effects of the time sampling interval on the angular combination characteristics were analyzed using a newly established angular combination number index (ACNI). Results show that a Moon-based platform can complement angular sampling observations from existing satellites. We found that the time sampling interval has different effects on the angular combination for different observed points. Accordingly, the Earth’s surface can be divided into two zones with respect to its sensitivity to the time sampling interval. When the time sampling interval increased from 10 min to 2 h, the maximum loss of the angular combination reached 50% for the observed points in the mid–low latitude zone.
Microburst, Windshear, Gust Front, and Vortex Detection in Mega Airport Using a Single Coherent Doppler Wind Lidar
Authors: Yuan Jinlong , Su Lian , Xia Haiyun , Li Yi , Zhang Ming , Zhen Guangju , Li Jianyu
Published: March 2022

Accurate wind shear detection is crucial for aviation safety, especially in landing and departure. A new approach for windshear alerting is proposed and demonstrated. This approach monitors orthogonal wind components in multiple runways using single coherent Doppler wind lidar (CDWL). First, the two orthogonal components of the wind field are retrieved from radial speed by an updated variational method. Then, the heading wind and cross wind on different runways are calculated simultaneously, without the location restriction of the single lidar. Finally, a windshear alerting message is generated through quantitatively evaluating the distribution of shear ramps over the monitoring area. The new CDWL-based approach for windshear alerting is implemented at the Beijing Daxing International Airport. The retrieved horizontal wind from the lidar is consistent with that from anemometers. Thanks to its high spatial/temporal resolution, some meteorological phenomena of aviation hazards, including microburst, windshear, gust front, and vortex are well captured. Particularly, all 10 windshear cases reported by crews are successfully identified during the windshear verification experiment, demonstrating the effectiveness and robustness of the new approach.
Areas Available for the Potential Sustainable Expansion of Soy in Brazil: A Geospatial Assessment Using the SAFmaps Database
Authors: Guarenghi Marjorie Mendes , Walter Arnaldo , Seabra Joaquim E. A. , Rocha Jansle Vieira , Vieira Nathália , Damame Desirée , Santos João Luís
Published: March 2022

Recently, soybean production almost doubled in Brazil, reaching 122 million tonnes, and it is expected to increase even more. Brazil is the world’s largest producer and is primarily an exporter. From a sustainability point of view, soy production has been strongly criticized mainly in relation to deforestation, albeit for indirect effects. Soybean oil is a potential feedstock for the production of bio-jet fuels, which needs to be sustainable according to international criteria (sustainable aviation fuels—SAF). This paper aims to estimate the areas still available for soy expansion in Brazil, considering conditions that would allow the production of SAF. We used the SAFmaps platform, a geospatial database with information on the most promising bioenergy crops for SAF and their supply chains. Just by displacing pastures and observing a set of constraints, the total area available for expansion was estimated at 192.8 thousand km2, of which 43% is of high suitability. These areas are concentrated in the Center-West region. Assuming a vertical supply chain, the results of the case studies of SAF production indicate potential feasibility, but some hypotheses considered are optimistic. Moreover, the results indicate that there can be sustainable production of soybean oil and contribution to the production of SAF.
Scattering Intensity Analysis and Classification of Two Types of Rice Based on Multi-Temporal and Multi-Mode Simulated Compact Polarimetric SAR Data
Authors: Guo Xianyu , Yin Junjun , Li Kun , Yang Jian , Shao Yun
Published: March 2022

Because transmitting polarization can be an arbitrary elliptical wave, and theoretically, there are numerous possibilities of hybrid dual-pol modes, therefore, it is necessary to explore the feature recognition and classification ability of compact polarimetric (CP) parameters under different transmitting and receiving modes to different ground objects. In this paper, we first simulated, extracted, and analyzed the scattering intensity of two types of rice of six temporal CP synthetic aperture radar (SAR) data under three transmitting modes. Then, during different phenology stages, the optimal parameters for distinguishing transplanting hybrid rice (T–H) and direct-sown japonica rice (D–J) were acquired. Finally, a decision tree classification model was established based on the optimal parameters to carry out the fine classification of the two types of rice and to verify the results. The results showed that this strategy can obtain a high classification accuracy for the two types of rice with an overall classification accuracy of more than 95% and a kappa coefficient of more than 0.94. In addition, and importantly, we found that the CP parameters in the 1103 period (harvest stage) were the best CP parameters to distinguish the two types of rice, followed by the 0730 (seedling–elongation stage), 0612 (seedling stage), and 0916 (heading–flowering stage) periods.
Is There a Sex Difference in Technical Skills among Youth Soccer Players in Norway?
Authors: Sørensen Arne , Haugen Emma , van den Tillaar Roland
Published: March 2022

Female soccer has recently experienced an impressive increase in the number of players, and an impressive improvement in the quality of elite matches. Still, studies show sex differences in match statistics on passing accuracy and the ability to control the ball in international matches, which is explained by a lower skill of level in female soccer players as compared to male players. Therefore, the aim of this study was to evaluate if female youth soccer players had bridged the gap in technical skills to reach the level that boys have traditionally attained. Sixteen male and 17 female youth soccer players of the same age and experience level took part in technical skill tests of reception of the ball on the ground and long passes. The results show a significant difference between the sexes in reception performance in favour of the male players (p < 0.05, ES = 1.09), but no significant difference in the long pass test (p = 0.11, ES = 0.43). This leads to the conclusion that the lower score on ball reception is probably the result of experience in small-sided self-organised soccer games during childhood among the male players, which influences reception skills but not the ability to make accurate long passes.
Baseline Assessment of Heavy Metal Pollution during COVID-19 near River Mouth of Kerian River, Malaysia
Authors: Akhtar Mohammad Nishat , Anees Mohd Talha , Ansari Emaad , Ja’afar Jazmina Binti , Danish Mohammed , Bakar Elmi Abu
Published: March 2022

River water quality is a serious concern among scientist and government agencies due to increasing anthropogenic activities and uncontrolled industrial discharge to rivers. The present study was conducted near the river mouth of the Kerian River to assess heavy metal pollution during COVID-19 pandemic-lockdown conditions and post-COVID-19 pandemic-unlock conditions. Twelve samples of shallow, middle, and bottom depths were collected at four locations along a 9.6 km reach. A concentration of eight heavy metals including Cadmium, Chromium, Copper, Iron, Manganese, Nickel, Lead, and Zinc were extracted through atomic absorption spectrometry. Total suspended solid was measured during laboratory experimentation. The results showed that, during the pandemic, concentrations of Nickel, Zinc, and Iron were high at shallow, middle, and bottom depths, respectively. Decreasing orders of heavy metal concentration are variable at different depths due to either their high sinking tendency with other existing components of water matrix or the anthropogenic source. However, almost all values of heavy metals are under the permissible limit of National Water Quality Standards of Malaysia and Food and Drug Administration. A possible reason for the lack of heavy metal pollution may be the restriction of anthropogenic activities during the COVID-19 pandemic. Additionally, no significant differences were observed in total suspended solid.
Can Digital Finance Contribute to the Promotion of Financial Sustainability? A Financial Efficiency Perspective
Authors: Luo Dan , Luo Man , Lv Jiamin
Published: March 2022

The research first summarizes the theoretical mechanism of digital finance to improve financial efficiency and sustainability; then, it proposes three hypotheses. After that, a DEA-BCC model and a super-efficiency DEA model are constructed to estimate a series of financial efficiency levels in 31 Chinese provinces. Utilizing the estimated financial efficiency values, this paper further tests each of the three hypotheses using both a random effects model controlling for cross-sectional correlation problems and an LSDV model, respectively. The findings show that (i) technological advance is the main driver of financial efficiency improvement in each region in China, while the role of scale effect in improving financial efficiency is weakening; (ii) the development of digital finance does significantly contribute to the improvement of regional financial efficiency; and (iii) the increase in both the breadth of coverage and depth of adoption of digital finance are core driving forces for the promotion of financial efficiency, with the breadth of digital financial coverage a stronger positive effect. Hence, this study can provide an important reference for policymakers and financial institutions to better understand the relationship amongst digital finance, financial efficiency, and sustainability as well as achieve sustainable financial inclusion.