bluuebunny/crossref_metadata_2025 huggingface dataset:
In vitro Antibacterial Properties of Etlingera elatior Flower Extracts against Acne-Inducing Bacteria: Propionibacterium acnes and Staphylococcus aureus
Authors: D Nurul Saidah , I Salwani , AB Mohd Hilmi , Z Mohd Khairi , U Rabiatul Adawiyah , S Nurul ‘Adani
Published: November 2020

Introduction: Acne is a common skin disorder and is generally caused by Propionibacterium acnes and Staphylococcus aureus. Etlingera elatior flower extract is known to have antibacterial properties however, the properties against these bacteria have not been extensively reported. Thus, this study aimed to investigate the antibacterial properties of the flower extract against these bacteria. Materials and Methods: The flower extract was subjected to sequential extraction using three different solvent polarities; n-Hexane, dichloromethane (DCM) and ethanol. The antibacterial properties were evaluated using the disc diffusion and broth dilution assays techniques by determining the inhibition zone diameter, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Total phenolic acids (TPC) and flavonoids contents (TFC) were estimated using Folin-Ciocalteu and aluminium-chloride colorimetric assay respectively. Morphological changes of the treated bacteria were studied using scanning electron microscope (SEM). Results: DCM flower extract showed the highest antibacterial properties against P. acnes; at 25 mg/ml it had the widest inhibition zone (11.39 ± 0.45 mm) and the lowest MIC (6.25 mg/ mL) and MBC (12.5 mg/mL). The ethanolic flower extract had the highest antibacterial properties against S. aureus; at 50 mg/ml­ the inhibition zone was 6.21 ± 0.25 mm and the MIC and MBC were both 12.5 mg/ mL. Ethanolic extracts had the highest TPC (966.304 ± 114.08 mg GAE/g) and TFC (796.33 ± 65.78 mg QE/ g). There was significant morphological changes of the treated bacteria observed under SEM. Conclusion: E. elatior flower extracts exhibited antibacterial properties against acne-inducing bacteria.
Role of the Immunohistochemical Marker (Ki67) in Diagnosis and Classification of Hydatidiform Mole
Authors: Deka FF Hasan Abu , ZH Abd Ali Al Saeng , Z Khalid Almukhtar
Published: November 2020

Introduction: Since the hallmark of gestational trophoblastic disease is trophoblastic proliferation, Ki67 is regarded as the best marker in studying hydatidiform mole.This study was conducted to evaluate the role of this proliferative marker in distinguishing among hydropic abortion, partial and complete hydatidiform mole. Materials and methods: This is a cross sectional study involving the application of Ki67 on a total of 90 histological samples of curetting materials from molar (partial and complete mole) and non molar hydropic abortion belong to Iraqi females, so three study groups were created. Immunohistochemical expression in villous cytotrophoblasts, syncytiotrophoblasts and stromal cells were recorded separately by three independent observers and the results were correlated statically. Results: The mean number of stained nuclei of villous cytotrophoblasts and stromal cells was the highest in complete mole and the lowest in non molar hydropic abortion. There is a significant statistical relationship regarding Ki67 labeling index in villous cytotrophoblasts between partial moles and hydropic abortion, complete mole and partial moles, hydropic abortion and complete mole. Regarding Ki67 labelling index in villous stromal cells, a significant statistical relationship achieved when the correlation done between partial mole and hydropic abortions, hydropic abortion and complete mole, while a non significant statistical relationship was achieved if the correlation done between partial and complete mole. All villous syncytiotrophoblasts showed negative results. Conclusion: Ki-67 labeling index in villous cytotrophblastic cells are useful in separating between partial moles and hydropic abortion, partial mole and complete mole, hydropic abortion and complete mole. While Ki-67 labeling index in villous stromal cells is only useful in separating between partial moles and hydropic abortion, hydropic abortion and complete mole.
Chyle Leak after a Simple Hemithyroidectomy: An Extremely Rare Situation
Authors: Muhammed Adi S , Suhaimi Shahrun N , Othman Suraya , Rashid Nor Faezan A , Muhammad Rohaizak
Published: November 2020

Chyle leak is a well-known complication that can occur after a thyroidectomy with neck dissection; however, it rarely occurs after thyroidectomy alone. Here, we report a case of chyle leak following a left hemithyroidectomy for a benign solitary thyroid nodule. Based on the literature search, this is only the second reported case of a chyle leak after a simple hemithyroidectomy without any central or lateral neck dissection. Amongst the possible causes, we hypothesize that the use of intraoperative nerve monitor may be a contributing factor. Treatment options are explored and the patient was treated successfully with nonoperative management.
Said Nursi’s Psycho-spiritual Therapy for Psychological Reactions of Patients with Physical Illnesses
Authors: Nabil MR Ahmad , MFM Tahir , NS Thomas , H Gülerce
Published: November 2020

Depression and anxiety are relatively common psychological reactions among those with chronic physical illnesses.1 It has been associated with low quality of life and impairment of daily functions.1 Cognitive behavioral therapy has been shown to be effective in helping patients to deal with maladaptive beliefs about their illnesses that predispose and perpetuate the psychological reactions.2 An event e.g. illness, may be interpreted differently by different individuals from a cognitive point of view.2 A person who attaches an unrealistic extravagant meaning to it, will result in an excessive emotional reaction. The cognitive content of a depressed patient centers on significant loss e.g. health, while an anxious patient harbors thoughts of imminent danger e.g. fear of loss.2
MUHASEBE DERSİ ALAN ÖĞRENCİLERİN MUHASEBE MESLEK ETİĞİ İLKELERİNE YÖNELİK ALGI DÜZEYLERİNİN ÖLÇÜLMESİ: AĞRI İBRAHİM ÇEÇEN ÜNİVERSİTESİ ÖRNEĞİ
Authors: ŞENDURUR Utku
Published: November 2020

Bu çalışmada, muhasebe öğrencilerinin etik kavramını algılamasına yönelik, farklı etik boyutlar ele alınarak bir analiz yapılmıştır. Çalışmada kullanılan veriler, Ağrı İbrahim Çeçen Üniversitesi’nde çeşitli muhasebe dersleri almış 198 öğrenciye anket uygulanarak elde edilmiştir. Veriler frekans analizi, ortalamalar, t-testi ve ANOVA gibi yöntemlerle analiz edilmiştir. Elde edilen bulgulara göre, Ağrı İbrahim Çeçen Üniversitesi’nde muhasebe dersi alan öğrencilerin, muhasebe meslek mensuplarının dürüstlük ve şeffaflık etik boyutlarını daha fazla ihlal ettiğini düşündükleri saptanmıştır. Ayrıca yapılan t-testi ve ANOVA sonuçlarına göre öğrencilerin etik algılarında staj yapıp yapmama, okudukları bölümler ve cinsiyetlerine göre gruplar arası anlamlı bir farka rastlanamamıştır
KUTSAL KİTAPLARA GÖRE HZ. NUH’UN GEMİSİ NEREDE YAPILDI, NEREDEN KALKTI, NEREDE İNDİ?
Authors: GEÇİT Mehmet Salih
Published: November 2020

Hz. Nuh, insanlığın ikinci atası olarak bilinir. O, Allah tarafından insanlara peygamber olarak gönderilmiş, 950 sene insanları Allah’ın dinine davet etmiştir. Ancak insanlar onun ortaya koyduğu apaçık delillere rağmen inkâr ve tekzip yolunu ikrar ve tasdike tercih etmişlerdir. Bununla yetinmeyerek bir de meydan okuyup azap ve mucize talebinde bulunmuşlardır. Hz. Nuh da küçük bir grup dışında tasdik etmediklerini görünce onlara yönelik beddua etmiştir. Bunun üzerine Nuh’un Tufanı diye bilinen olay yaşanmıştır. Bu olaydan önce Allah’ın emri ile bir gemi inşa ederek iman getirenlerin kurtuluşuna vesile olmuştur. İşte bu gemi hakkında birçok tartışma ve inceleme yapılmaktadır. Söz konusu inceleme ve tartışmalarda olayı gündeme getirip insanlığa mesaj veren ayetlerdeki hikmet ve ibretlik noktaları tespit edip yeniden hatırlatmaktan ziyade geminin nereye indiği noktası üzerinde durulmaktadır. Geminin nereye indiği tartışılırken, geminin nerede yapıldığı hususunun gündeme getirilmediği dikkat çekici bir durumdur. Biz de bu makalemizde yapılmakta olan tartışmalara iki boyut daha kazandırmak istiyoruz: Gemi nerede yapıldı, nereleri gezip dolaştı ve nereye indi. Bu şekilde geminin mecrasını ve kalkış ve iniş sürecini Kutsal Kitaplar bağlamında inceleyeceğiz.
Batı Felsefesinde Feminizmin Dini Kökeni
Authors: ÇAĞIL Abdullah
Published: November 2020

Batı felsefesinde feminist düşüncenin mücadele etmesi gereken alanlardan biri de dini anlayış tarafından belirlenen düşünce ve eylem alanıdır. Din ile kültürün ortak etkileşimleri nedeniyle bazen bu iki kavramın etkisi birbirine karışabilmektedir. Bu karışıklığın önüne geçebilmek için doğrudan dini metinleri dikkate almak gerekecektir. Böylece hem toplumsal etkilerinin gücü hem de problemi daha net anlatması bakımından önümüzde sadece İncil ve Tevrat kalacaktır. Bu iki kutsal metnin belirlediği düşünce ikliminde feminist hareketleri tahrik eden bir anlayışın yeşerdiğini söyleyebiliriz. Yaratılış hikâyesiyle başlayan dini anlatı, kadın cinsini hem ikinci rolde hem de baştan çıkaran bir kötülüğe boyun eğmiş olarak resmeder. Ancak bu, anlatının eril bir yorumudur ve feminist bir yeniden yorumlama biçiminde resim başka bir şekilde görünecektir. Dolayısıyla kadın felsefe, hukuk, tarih ve sosyoloji alanında olduğu gibi dini alanda da sonradan yaratılmış bir algının kurbanı olarak karşımıza çıkacaktır.
Apparently Spontaneous Partial Rupture of Anterolateral Papillary Muscle Requiring Urgent Surgery
Authors: Fazzari Fabio , Rossetto Ludovico , Maria Bragato Renato , Curzi Mirko , Donghi Valeria , Mantovani Riccardo , Novo Giuseppina , Fazzari Fabio
Published: November 2020

Papillary muscle rupture is a rare complication of myocardial infarction. Here we describe a case of an
apparently spontaneous rupture of papillary muscle, not associated with coronary obstruction. The patient
was a 73-year-old man admitted to our hospital for diabetic ketoacidosis complicated by acute pulmonary
edema and cardiogenic shock. Transthoracic and transesophageal echocardiography showed partial rupture
of papillary muscle leading to severe mitral regurgitation. Urgent cardiac surgery with mitral valve
replacement was performed.
Innervation Anomalies and Interneural Anastomoses: Is There Clinical Relevance or Not?
Authors: Dmytriiev Dmytro , Dmytriiev Kostiantyn , Lysak Yevhenii
Published: November 2020

Failed block could be one of the adverse results of the conductive anaesthesia. There are situations, when in seemingly perfect technique of the block, properly chosen drug, dosage, adjuvant – the block is not achieved (it does not occur or is incomplete or so-called “mosaic block” occurs). It is necessary to remember about atypical or abnormal nerves branching, possible interneural anastomoses, when looking for the possible cause of it. Information about most common types of interneural anastomosis of arm’s and leg’s long nerves is presented in this article. Knowledge of possible abnormal neural innervation can provide an understanding of inefficacy of some simple blocks, decrease amount of mistakes in data interpretation, that was obtained during electroneuromyographic (ENMG) investigations, improve understanding of clinical pattern in the peripheral nerve injuries, that form anastomosis.
Foreign Trade of the Democratic Republic of the Congo and the Share of Agricultural Products for Export
Authors: Kalala Jean Rene , Hanchar Andrei , Witkowska-Dąbrowska Mirosława
Published: November 2020

Despite its numerous resources, the Democratic Republic of the Congo is one of the poorest countries in the world. The DRC also has underutilised resources of arable land and good conditions for agricultural production. This study analysed changes in the volume of foreign trade in the DRC and assessed the share of its agricultural exports in the years 2015-2019. The analysis covered the volume of total imports and exports, as well as imports and exports by sector. The foreign trade balance and the dynamics of change in the years under analysis were calculated. Structural indicators as well as fixed and variable-based dynamic indices were used. As a result of the conducted research, fluctuations in the export of all goods were found along with a decrease in the export of numerous significant agriculturally produced goods: rubber, palm oil and medicinal plants.
Time Series Decomposition as a Method of Measuring Capital Markets Convergence
Authors: Żukowski Rafał
Published: November 2020

The aim of the article is to present time series decomposition as a method of measuring capital markets convergence. As an example, convergence of two different sets of markets are measured using this methodology. On the basis of this research, it has been established that time series decomposition of the market indices can prove or reject a hypothesis of moving indices in similar directions over a period of time.
Main Pharmacological Strategies Against SARS-CoV-2
Authors: Fontes Thais Gonçalves , Destefani Afrânio Côgo
Published: November 2020

There are currently no specifi c drugs for COVID-19. However, several drugs approved for other situations, as well as several investigative agents, are being studied for the treatment of COVID-19 in several hundred clinical trials worldwide. In anticipation of the results of clinical trials, different medical actors around the world have used drugs empirically and with unknown safety profi les. It should be noted that emerging data demonstrated that cardiovascular comorbidities are very common in patients with COVID-19 and that these patients are at increased risk of death. To trace a path of light through the cloudiness that we live on COVID 19, we conducted a bibliographic search, aiming, mostly, to present concise, relevant and scientifi c information. The main groups of drugs and their adverse effects and drug interactions were raised. Specific concerns in patients with COVID-19 include underlying structural heart disease, cardiac injury, kidney and liver dysfunction, limited resources for cardiac monitoring and drug interaction. Clear administration protocols must be in place in all hospitals and clinics that use drugs for the treatment of COVID-19, to assist in research and analysis of possible drugs capable of inhibiting the virus without consequent complications.
Evaluation of Thyroid Hormones and AntiThyroglobulin Antibodies among Sudanese Polycystic Ovarian Syndrome Patients
Authors: KAMIL Rofida Abuobaida , ABUBAKER Nuha Eljailli , MOHAMED Seifeldeen Ahmed , IBRAHIM Mariam Abbas , ABD ALLA Ahmed Bakheet
Published: November 2020

Background: Polycystic ovarian syndrome (PCOS) and thyroid disorders are the most common endocrine disorders in women. Evidently, the involvement of polycystic ovarian syndrome (PCOS) and thyroid autoimmunity triggering thyroid disorders has not yet occurred. Objective: The aim was to assess serum free tri-iodothyronine (FT3), free thyroxin (FT4) and anti-thyroglobulin antibodies among polycystic ovary syndrome Sudanese patients. Materials and methods: Fifty Sudanese patients diagnosed with PCOS and 50 healthy age matched females were recruited in this cross-sectional controlled study. Serum FT3 and FT4 were measured by an immunoassay analyzer and
serum anti-thyroglobulin antibodies were measured using ELISA. The data was then analyzed using the SPSS. Results: The results showed a signifi cant increase in serum FT3 and anti-thyroglobulin antibodies and there was no statistical difference in PCOS serum FT4 levels compared to the control group. The results revealed no correlation between levels of FT3, FT4 and anti-thyroglobulin antibodies with age; also there were no correlation between levels of FT3 and FT4 with BMI while there was a positive correlation between anti-thyroglobulin antibodies levels and BMI. Conclusion: Patients with PCOS had elevated FT3 and antithyroglobulin. Therefore, the assessment of
thyroid autoantibody with thyroid hormones in patients with PCOS should be investigated.
Screening Criteria for Colorectal Cancer for Patients with Type II Diabetes Mellitus
Authors: AGACHE Alexandra , BOTEA Sabin , MUSTATEA Petronel , BOBIRCA Florin
Published: November 2020

Colorectal cancer and diabetes mellitus represent a major public health issue, fi rst, by the number of new cases which are at an alarming rate. Secondly, by the negative effect over the quality of life, socio-economic status and lifespan, representing high morbidity and mortality causes. Diabetes Mellitus is the disease of the century with a global prevalence (standardised-age) which doubled since 1980, rising from 4.7% to 8.5% in adult population. In 2012, the estimated number of fatalities caused by diabetes mellitus and other related complications were at 3.7 million, out of which 43% were patients under the age of 70. Neoplasia represents the second cause of death, after cardiovascular disease. Colorectal cancer (CRC) ranks the 3rd regarding the global neoplasia incidence (10.2%) and the second regarding the mortality (9.5% of all cancer deaths). Colorectal cancer screening refers to the periodic evaluation of asymptomatic patients at risk of developing this neoplasia. Colorectal cancer has a number of peculiarities that make it ideal for screening. Since the end of the 19th century, the suspicion has been raised that diabetes mellitus has been involved, through directly etiological mechanisms, in carcinogenesis (breast, endometrium, colorectal, pancreas, liver, non-Hodgkin lymphoma). At the moment, there is already a consensus in the literature on the role of diabetes as an independent risk factor for colorectal cancer. However, despite the existence of numerous experimental evidence, epidemiological studies and meta-analyses, there is currently no adaptation of colorectal cancer screening for these patients. Material and method: Prospective case-control study conducted over a 2-year period including a number of 442 patients presented at „Dr. I Cantacuzino” Clinical Hospital, asymptomatic, who underwent lower digestive endoscopies in order to assess and defi ne using anamnestic, clinical and paraclinical
criteria, the profi le of the patient with type II diabetes mellitus that should be given an endoscopic examination because diagnosing precursor lesions or even CRC is likely probable. Results: In the analyzed group, statistically signifi cant correlations (p<0.05) were recorded between positive colonoscopy results (defi ned as precursor lesions
– polyps- or tumors) and certain clinical characteristics (age, sex, BMI, duration of diabetes, type of antidiabetic treatment) and also paraclinical (reactive C protein and glycated hemoglobin). Conclusions: Criteria of patients with type II diabetes who have the maximum probability of developing colorectal cancer have been outlined. Thus this
patient is more likely male, with a BMI > 25, aged over 60 years, with an unbalanced diabetes mellitus counted by HbA1c > 7 mg/dL, with over 5 years of diabetes evolution, in treatment with insulin most likely or combined insulin with oral antidiabetics and with an inflammatory biological profi le expressed by PCR> 2 mg/dL threshold values.
Abdominal Pseudocyst in the Vicinity of Calcified Renal Allograft in a Patient with Peritoneal Dialysis - Case Report
Authors: RADULESCU Daniela , GEORGESCU Dragos Adrian , ANGELESCU Andrei , GEAVLETE Bogdan Florin
Published: November 2020

Abdominal pseudocysts are rarely reported in peritoneal dialysis and usually arise secondary to repeated dialysisrelated peritonitis. We present the case of a patient with end-stage renal disease treated for 9 years by continuous ambulatory peritoneal dialysis that developed an abdominal pseudocyst in the vicinity of the non-functional and
calcifi ed renal graft. Because the adequacy of peritoneal dialysis was optimal, surgical removal of the invaginated peritoneum and closure of the breach allowed the patient to continue peritoneal dialysis treatment.
Dysregulation of Insulin-Linked Metabolic Pathways in Alzheimer’s Disease: Co-Factor Role of Apolipoprotein E ɛ4
Authors: Robbins James , Busquets Oriol , Tong Ming , de la Monte Suzanne M.
Published: November 2020

Background:

Brain insulin resistance and deficiency are well-recognized abnormalities in Alzheimer’s disease (AD) and likely mediators of impaired energy metabolism. Since apolipoprotein E ( APOE) is a major risk factor for late-onset AD, it was of interest to examine its potential contribution to altered insulin-linked signaling networks in the brain.

Objective:

The main goal was to evaluate the independent and interactive contributions of AD severity and APOE ɛ4 dose on brain expression of insulin-related polypeptides and inflammatory mediators of metabolic dysfunction.

Methods:

Postmortem fresh frozen frontal lobe tissue from banked cases with known APOE genotypes and different AD Braak stages were used to measure insulin network polypeptide immunoreactivity with a commercial multiplex enzyme-linked immunosorbent assay (ELISA).

Results:

Significant AD Braak stage and APOE genotype-related abnormalities in insulin, C-peptide, gastric inhibitory polypeptide (GIP), glucaton-like peptide-1 (GLP-1), leptin, ghrelin, glucagon, resistin, and plasminogen activator inhibitor-1 (PAI-1) were detected. The main factors inhibiting polypeptide expression and promoting neuro-inflammatory responses included AD Braak stage and APOE ɛ4/ ɛ4 rather than ɛ3/ ɛ4.

Conclusion:

This study demonstrates an expanded role for impaired expression of insulin-related network polypeptides as well as neuroinflammatory mediators of brain insulin resistance in AD pathogenesis and progression. In addition, the findings show that APOE has independent and additive effects on these aberrations in brain polypeptide expression, but the impact is decidedly greater for APOE ɛ4/ ɛ4 than ɛ3/ ɛ4.
Water Scarcity and Challenges for Access to Safe Water: A Case of Bangladesh’s Coastal Area Vulnerable to Climate Change
Authors: Talukder Mohammad Radwanur Rahman , Rutherford Shannon , Islam Khairul , Chu Cordia
Published: November 2020

Existing efforts to ensure safe water access in coastal Bangladesh are challenged by increasing freshwater salinity. This research explored/explores safe water consumption choices in coastal Bangladesh, which data are scarce to date, using a mixed-methods approach. In 2014, a cross-sectional survey was conducted in southwestern coastal Bangladesh (n=261) and data was generated on water supply and consumption. Data collection also involved 29 in-depth interviews of household care givers and focus group discussions were performed with three community groups. Descriptive statistics were applied to analyse quantitative data and thematic analysis was used for qualitative data. The survey showed that 60% of the study population used tube well water while 40% used pond water for drinking. It was observed that for cooking purposes, the use of pond water was slightly higher than the tube well water. Only 13% of the respondents mentioned that their drinking water tasted salty whereas 6% of the respondents reported health problem (diarrhoea, dysentery, gastric issues and skin problems) after using these water sources. The qualitative data reveals that water available for drinking and cooking is causing a serious threat to this coastal community, particularly during the dry season. In-depth assessments indicated that drinking water choices were less driven by concerns for health than practical issues such as travel distance and time taken and taste. The palatability of water was an important determinant of choice for drinking and other domestic uses. Furthermore, the utility of alternative options for safe drinking water is driven by beliefs and traditions and source maintenance. Given the increasing salinisation of freshwaters in many low-lying countries and likely exacerbation related to climate change-induced sea level rise, therefore, promotion of low saline drinking water along with salt reducing interventions consider that community beliefs and practices must be a made priority.
Clustering of Groundwater Wells and Spatial Variation of Groundwater Recharge in Sina Basin, India
Authors: Roshni Thendiyath , Nayahi Jesu V. , Jha Madan K. , Nehar Mandal , Sourav Choudhary , Wable Pawan S.
Published: November 2020

A spatial and temporal analysis of groundwater levels, topography, and precipitation is required to properly manage the groundwater resource. The present paper explains it in two parts: (1) spatial analysis of groundwater levels and selection of suitable clustering approach for selection of representative wells and (2) spatial and temporal variations of groundwater recharge calculated by three numerical models: Chaturvedi model, Amritsar model and ERAS model. Four clustering techniques including K-Means clustering algorithm, Hierarchical clustering technique, canopy and expectation maximisation (EM) were used for the clustering of groundwater levels. Among these, the canopy technique presents more reliable results compared to the other techniques for the spatial analysis of groundwater levels and the formation of representative wells in the Sina basin. For the groundwater recharge estimation, Chaturvedi model and ERAS model values were found very close. The recharge values show consistency with the precipitation data and found that 15% of precipitation contributes to annual groundwater recharge. Spatio-temporal variation of groundwater recharge correlated with precipitation is also carried out for the selected basin. The results show a drastic decline in the groundwater recharge from the year 1990 to 2008. An empirical expression is also developed for groundwater recharge estimation in terms of groundwater level. This provides regional scale information about the basin and helps to understand the groundwater exploitation scenario for instance.
Hydrogeochemistry and Overall Appraisal of Groundwater Status of Taldangra Block, Bankura District, West Bengal, India
Authors: Palmajumder Moumita , Chaudhuri Susanta , Das Vikas K. , Nag Sisir K.
Published: November 2020

South-western districts of the state of West Bengal, India are considered to be a significantly water-stressed area of the state because of unfavourable geological setting, subsurface lithology, soil cover and surface drainage pattern. Updated geohydrological data on micro-scale i.e., at subdivision or block-level are scanty for Bankura District, West Bengal. For the present study, a geo-hydrological survey was conducted in Taldangra block of Bankura District, West Bengal, during post and pre-monsoon session of 2017–18, to obtain an intense status on present groundwater quality of this water-stressed block. Variation of concentration of major affecting ions and spatial-temporal seasonal variations of water table elevation head and subsurface shift of predominant recharge and discharge zones of the block were demarked explaining the possible reasons. Suitability status of the groundwater for drinking, domestic and irrigation usages was also rated by the estimation of sodium adsorption ratio (SAR), soluble sodium percentage (SSP), permeability index (PI), Piper trilinear diagram.
Global existence, asymptotic behavior and uniform attractor for a non-autonomous Timoshenko system of type III with weak damping
Authors: Qin Yuming , Sheng Ye
Published: November 2020

In this paper, we investigate one-dimensional thermoelastic system of Timoshenko type III with double memory dampings. At first we give the global existence of solutions by using semigroup theory. Then we can prove the energy decay of solutions by constructing a series of Lyapunov functionals and obtain the existence of absorbing ball. Finally, we prove the asymptotic compactness by using uniform contractive functions and obtain the existence of uniform attractor.
Social Network Optimization for Cluster Ensemble Selection
Authors: Zhao Chenyue , Alizadeh Hosein , Minaei Behrouz , Mohamadpoor Majid , Parvin Hamid , Mahmoudi Mohammad Reza
Published: November 2020

This paper studies the cluster ensemble selection problem for unsupervised learning. Given a large ensemble of clustering solutions, our goal is to select a subset of solutions to form a smaller yet better performing cluster ensemble than using all available solutions. The common way of aggregating the chosen solutions is accumulating the information of the selected results to a similarity matrix. This paper suggests transforming the similarity matrix to a modularity matrix and then applying a new consensus function which optimizes modularity measure in it. We represent the modularity maximization problem as a 0-1 quadratic program which can be exactly solved for small datasets. We also established a new greedy algorithm, namely sum linkage, to optimize the objective function specially for large scale datasets in a very short time. We show that the proposed consensus partition gets much closer to the actual cluster structure than the partitions obtained from the direct application of common cluster ensemble methods. The promising results compared with other most cited consensus functions show the excellent efficiency of the proposed method.
Neuromodulation in the Treatment of Alzheimer’s Disease: Current and Emerging Approaches
Authors: Pople Christopher B. , Meng Ying , Li Daniel Z. , Bigioni Luca , Davidson Benjamin , Vecchio Laura M. , Hamani Clement , Rabin Jennifer S. , Lipsman Nir
Published: November 2020

Neuromodulation as a treatment strategy for psychiatric and neurological diseases has grown in popularity in recent years, with the approval of repetitive transcranial magnetic stimulation (rTMS) for the treatment of depression being one such example. These approaches offer new hope in the treatment of diseases that have proven largely intractable to traditional pharmacological approaches. For this reason, neuromodulation is increasingly being explored for the treatment of Alzheimer’s disease. However, such approaches have variable, and, in many cases, very limited evidence for safety and efficacy, with most human evidence obtained in small clinical trials. Here we review work in animal models and humans with Alzheimer’s disease exploring emerging neuromodulation modalities. Approaches reviewed include deep brain stimulation, transcranial magnetic stimulation, transcranial electrical stimulation, ultrasound stimulation, photobiomodulation, and visual or auditory stimulation. In doing so, we clarify the current evidence for these approaches in treating Alzheimer’s disease and identify specific areas where additional work is needed to facilitate their clinical translation.
Use of firefly optimization algorithm for fractional fourier transform based reversible data hiding
Authors: Amsaveni A. , Bharathi M.
Published: November 2020

This paper presents a Fractional Fourier transform based reversible data hiding technique to secure the data transmitted over communication network. The proposed algorithm modifies the cover image to improve the robustness of data hiding technique. The cover image is transformed using Fractional Fourier Transform (FrFT) into a time-frequency domain and the optimal pixel locations for hiding the secret data are found using firefly algorithm. Firefly algorithm uses multi-objective function, which is a combination of Structural Similarity Index Measure (SSIM) and Bit Error rate (BER). The histogram shifting technique embeds secret data in the optimal pixel locations. The quality of test images is analyzed under varying payload as well as under varying fractional order. Experimental results conclude that this scheme produces good quality stego image. It has also been found from the simulation results that the proposed algorithm is more robust and reversible against various attacks as it provides lower bit error rate and higher normalization coefficient.
Diagnosing X-linked Myotubular Myopathy – A German 20-year Follow Up Experience
Authors: Gangfuss Andrea , Schmitt Dirk , Roos Andreas , Braun Frederik , Annoussamy Melanie , Servais Laurent , Schara-Schmidt Ulrike
Published: November 2020

X-linked myotubular myopathy (XLMTM) is a life-threatening rare neuromuscular disease, which is caused by pathogenic variants in the MTM1 gene. It has a large phenotypic heterogeneity, ranging from patients, who are able to walk independently to immobile patients who are only able to bring hand to mouth and depend on a respirator 24 hours a day every day. This suggests that ventilator requirements may not illustrate the full clinical picture of patients with XLMTM. At present, there is no curative therapy available, despite first promising results from ongoing gene therapy studies.

In this study, we evaluated in detail the data from 13 German XLMTM patients, which was collected over a period of up to 20 years in our university hospital. We compared it to the international prospective longitudinal natural history study (NHS) data from 45 patients (containing 11 German patients). To highlight the broad phenotypic spectrum of the disease, we additionally focused on the clinical presentation of three cases at a glance.

Comparing our data with the above mentioned natural history study, it appears the patients of the present German cohort seem to be more often severely affected, with higher frequency of non-ambulatory patients and patients on ventilation (and for longer time) and a higher proportion of patients needing a percutaneous endoscopic gastrostomy. Another key finding is a potential gap in time between first clinical presentation and final diagnosis, showing a need for patients to be treated in a specialized center for neuromuscular diseases.
Characterization of Hippocampal Histomorphology Following R. vomitoria Root Extract Treatment
Authors: Ekong Moses B. , Ekpene Ubong , Nwakanma Agnes A. , Mbadugha Christopher C.
Published: November 2020

Rauwolfia vomitoria Afzel. is an antipsychotic plant used by several African communities in the management of psychiatric conditions with good outcomes. Concerns about its dosages on brain activity lead to this investigation of its action on the hippocampal microstructure. Twenty-four adult male Wistar rats of average weight 200 g, were assigned into four groups (n = 6): control; 200, 300 and 400 mg/kg body weight of RV root bark extract, respectively. The administration was once daily, and orally for seven days. Daily observation of the animals was done till on day eight when they were sacrificed after deep anaesthesia. Each brain was processed for histology and immunohistochemical studies.

Animals in the 200, 300 and 400 mg/kg RV groups appeared generally dull and drowsy, and barely fed. Their hippocampal histology showed neuronal atrophy and karyorrhexis, with no difference in cell count, although the pyramidal cell numbers decreased in the 300 and 400 mg/kg RV groups. Neuron-specific enolase decreased in the 400 mg/kg RV group, while neurofilament decreased in all test groups. Glial fibrillary acidic protein expression and density increased in the 200 and 300 mg/kg RV groups, but not the 400 mg/kg RV group, all compared with the control group. The given doses of RV root bark extract in adult Wistar rats showed sedative activities with hippocampal histopathological changes, which may not be reversible, thereby leading to the hippocampal functional deficit.
A gépjármű-diagnosztika oktatásának változásai az NKE HHK Haditechnikai Tanszékén
Authors: Gyarmati József , Jusztin Karina Zelma , Vég Róbert László
Published: November 2020

A gépjárművek fejlődése jelen korunkban felgyorsult, egyre összetettebb és modernebb járműveket használunk, amely járműveket a Magyar Honvédség állományában is rendszeresítenek és rendszeresítettek. E járművek technikai kiszolgálása és javítása csak modern diagnosztikai eljárások alkalmazásával valósítható meg. Jelen katonai logisztika alapképzési szak tantervében is megtalálható a gépjármű-diagnosztika tantárgy, mint ahogyan a korábbi tantervekben is jelen volt, és fontos részét képezi az oktatásnak. A honvéd tisztjelölteknek első tiszti beosztásuk eredményes ellátásához ismerniük kell az eszközök felépítése mellett a részegységek ellenőrzését és hibabehatárolását is. A gépjármű-diagnosztika oktatása nagymértékben igényli a megfelelő oktatástechnikai ellátottságot, mind mennyiségben, mind minőségben. A cikk bemutatja az elmúlt évben végrehajtott diagnosztikalabor-fejlesztést, a fejlesztés által létrejött képességnövekedést.
A MIMO-technológia polgári és katonai alkalmazási lehetőségei
Authors: Virágh Krisztián
Published: November 2020

A MIMO-t, azaz a több bemenettel és több kimenettel rendelkező rádiókommunikációs technológiát manapság egyre több területen alkalmazzák. Az újabb generációs mobilhálózatok – különös tekintettel a 4G LTE-re és az 5G-re –, valamint még sok más RF-technológia (például WiMAX, Wi-fi) élvezi a MIMO által szolgáltatott megnövekedett csatornakapacitás és a megbízhatóság előnyeit. Természetesen ezeket nemcsak a polgári életben lehet kihasználni, hanem a katonai felhasználások területén, például radar-, harcászati rádió- vagy pilóta nélküli légijármű-rendszerek (UAS) esetén is. A jelenleg is folyamatban lévő honvédelmi és haderőfejlesztési program jelentős anyagi forrásokat biztosít a Magyar Honvédség számára a technikai eszközrendszer modernizációjára, ugyanakkor a kommunikációs megoldások fejlesztéséről mostanáig nem sokat lehetett megtudni. Véleményem szerint a program célkitűzéseivel összhangban olyan irányú fejlesztések is indokoltak lehetnek, amelyek a MIMO-technológia minél szélesebb körű jövőbeni katonai alkalmazására irányulnak.
A WRC–19 hatása a katonai spektrumhozzáférésre
Authors: Drilla Attila
Published: November 2020

Jelen cikk megírásával az a szándékom, hogy felhívjam a katonai közösség figyelmét egy olyan eseményre, ami alapvetően határozza meg a védelmi célú, azon belül is a katonai célú, rádióspektrumhoz történő hozzáférést, röviden spektrumhozzáférést. Ez az esemény nem más, mint az ITU-R Rádiótávközlési Világértekezlete. Az esemény fontosságát jól tükrözi a NATO-szövetségen belül a spektrumgazdálkodásért felelős Spektrumképesség Panel munkája, valamint az értekezletre történt felkészülési folyamat. Végül, de nem utolsósorban a világértekezlet azon napirendi pontjait mutatom be röviden, amelyek a NATO katonai rendszereinek működési frekvenciatartományait érintették, valamint az egyes napirendi pontok esetében elért eredményeket, hogyan befolyásolták a katonai spektrumhozzáférést, esetleg okozhatnak-e katonai spektrumeróziót.
A vegyi fegyverek és az igazságos háború
Authors: Őze Zoltán
Published: November 2020

Az ABV-fegyverek jelentette fenyegetés évek óta növekszik a technológiai fejlődés és a változó politikai környezet hatására. A nukleáris fegyverek terjedése és a vegyi fegyverek folyamatos felbukkanása a fegyveres konfliktusokban rávilágított a nemzetközi biztonsági garanciák törékenységére. A tömegpusztító fegyverek megszerzésére törekvő államok egyfajta elrettentő erőként, biztonsági garanciaként tekintenek ezekre a fegyverekre. Lehet-e igazságos egy háború, amelyben a tömegpusztító fegyverek áldozatai főként ártatlan civilek? Igazolhatja-e a jogos önvédelem e fegyverek alkalmazását? Belefér-e a Katolikus Egyház igazságos háborúról alkotott nézeteibe a vegyi fegyverek alkalmazása?
Magyarország Nemzeti Biztonsági Stratégiája (2012) a mai biztonságpolitikai kihívások tükrében
Authors: Beregi Alexandra Lilla
Published: November 2020

A tanulmány célja, hogy bemutassa Magyarország Nemzeti Biztonsági Stratégiáját (2012) a mai biztonságpolitikai trendek tükrében. A dolgozat tézise szerint a stratégiában szereplő, Magyarországot meghatározó biztonságpolitikai környezet, biztonságpolitikai érdekek, biztonsági fenyegetések, kihívások és azok kezelése, valamint a stratégia végrehajtásának eszközrendszere a globális biztonságpolitikai trendek hatására elavult és idejétmúlt. Napjaink legmeghatározóbb biztonságpolitikai kihívásai a (1) globalizáció; (2) digitalizáció; (3) globális felmelegedés és a (4) nyersanyagforrások kimerülése. Ezért szükséges egy olyan új stratégia megírása, amely összhangban áll a globális, kiváltképp az európai biztonsági trendekkel, amelyek mentén meghatározhatók Magyarország biztonságpolitikai kihívásai és azok kezelésének lehetőségei.
A tűzvédelmi helyzet fenntartásának fő elemei az épületek létesítése és használata során
Authors: Gyapjas János
Published: November 2020

Az épületek biztonságos, rendeltetésszerű használatát a tűzvédelmi helyzet folyamatos, megfelelő szinten tartása garantálja. A tanulmány fő célja az ezt szavatoló fő hazai tényezők azonosítása. Az elvárt tűzvédelmi biztonsági szintet hazánkban az Országos Tűzvédelmi Szabályzat határozza meg [1: 3/A. §]. A tűzvédelmi helyzet saját megfogalmazásom szerint az épület egy olyan tűzvédelmi szempontú állapota, ami teljesíti ezt a szintet. Egy épület a használata során akkor éri el ezt a létesítésekor beállított biztonsági szintet, ha minden életszakaszában folyamatosan biztosított az ennek megfelelő tűzvédelmi helyzet. A vizsgálat a kapcsolódó szabályozás elemzésén alapul, különös tekintettel a speciális tűzvédelmi dokumentációs, a személyi jellegű követelményekre és a hatóság közreműködésére. Az elemzés sorvezetőként használja az épületek jellemző életszakaszait. A vizsgálat eredménye megalapozhatja a tűzvédelmi helyzet fenntartásának modelljét. Egyúttal a tanulmány összegyűjti a hazánkban gyakran alkalmazott tűzvédelmi kockázati tényezőket, és javaslatokat tesz további kutatási irányokra, a szabályozás optimalizálására.
A magyarországi volt szovjet katonai repülőterek természetre gyakorolt hatásai és jelenlegi állapotuk
Authors: Szabó László István
Published: November 2020

Magyarországon a második világháborútól a varsói szerződés felbomlásáig állomásoztak szovjet katonai alakulatok, amelyek létszámáról, tevekénységéről pontos információk ma sem állnak a kutatók rendelkezésére. Hazánkban 1991-ig több szovjet katonai repülőtér működött. A szerző ebben a cikkben részletesen ismerteti ezek működésének történetét, bemutatja jelenlegi funkciójukat, műszaki állapotukat. Vizsgálja, hogy működésük során, valamint mostani állapotukban milyen káros hatást gyakoroltak és gyakorolnak ma is a környezetükre, továbbá milyen lehetséges következményekkel kell számolni. A fentieken túl a szerző átfogó képet ad a repülés és a repülőterek működésének környezetterhelő hatásairól, valamint ismerteti a károk felszámolásának lehetséges formáit és módszereit. Végezetül javaslatot tesz a hazai szovjet repülőterek okozta környezeti károk felszámolásának folyamatára és a létesítmények további hasznosításának lehetőségeire.
Településeken kívül eső lakott ingatlanok tűzoltói beavatkozásainak sajátosságai egy konkrét eset elemzésével
Authors: Bányai Tamás , Pántya Péter
Published: November 2020

Számos esetben kell lakott belterületen kívüli ingatlanoknál beavatkozni a tűzoltó erőknek, gyakran nehéz körülmények között. Látható, hogy tartósan növekszik a külterületeken életvitelszerűen élő lakosság száma, mind népszerűbb a tanyaszerű elszigeteltség igénye, de a városokból a természet közelébe költözés (Wildland-urban Interface megközelítés) is egyre inkább teret hódít. Jelen cikkben vizsgáltak alapján nem a klasszikus mezőgazdasági területek, hanem a tanyákon és egyéb lakott külterületen életvitelszerűen tartózkodó embereket érintő tűzvédelem növelése a cél. Immár egész évben számolnunk kell az ilyen területen fekvő építmények lakáscélú újrahasznosításával és így a kárelhárításban részt vevő szervezeteket érintő nehezebb kárfelszámoló tevékenységgel. Ezek adott esetben rendhagyó vezetői gondolkodást és speciális tűzoltótechnikai felszereléseket, nagy létszámú tűzoltó erőt igényelnek, és időben elhúzódhatnak.
Coffe Coffee Seed Waste silage technology as goat feed in Tigapanah Sub-district, Karo regency
Authors: Patriani Peni patriani
Published: November 2020

Coffee is a plantation that produces waste in its processing such as coffee seed waste. Farmers do not know the nutritional content of coffee seed waste is the cause of the waste not being used as animal feed. Coffee bean waste has high water content and caffeine which reduces the cattle's palpability. The solution is to use coffee seed waste silage technology. The method used in community service programs is by approaching, interviewing, exploring problems, and finding solutions to problems. Learning methods using books on how to make silage, providing brochures, banners, and shows that interest farmers. Outputs of this community service program; 1) Increasing the community who use plantation waste as animal feed to reduce feed costs 2) Development of integrated business concepts between livestock and logging. 3) Increased knowledge and skills of farmers 4) Utilization of coffee bean skin waste can reduce environmental pollution. The results that have been obtained are based on observations of the indicators, namely an increase in the number of farmers utilizing coffee fruit husk waste as animal feed, increased knowledge of farmers, increased integrated business cooperation between livestock and plantations, and decreased pollution of environmental waste.
Find Opportunities Within USDA Programs to Reduce GHG Emissions and Increase Carbon Sequestration
Authors: Swanston Chris , Schmitt Kristen , Shannon Danielle , Daley Jad
Published: November 2020

The USDA Northern Forests Climate Hub (NFCH) and the Forest-Climate Working Group (FCWG) held a series of two workshops designed to identify specific opportunities within USDA programs to explicitly
support greenhouse gas mitigation in the forest sector. The first workshop (Perspectives from the Field)
gathered suggestions and ideas from field practitioners familiar with using USDA programs to support forest carbon benefits. The second workshop (Finding USDA Programmatic GHG Mitigation Opportunities) invited USDA Program leads and representatives to develop specific suggestions on modifications to USDA Programs that could assist in these efforts. The final outcome was a series of twelve ideas from USDA Program leads and representatives that took into account input from the field, and outlined specific needs for each idea. These twelve are listed below and summarized more
completely in the Workshop summary section description.
Climate Change Field Guide for Northern Minnesota Forests: Site-level considerations and adaptation
Authors: Handler Stephen , Janowiak Maria , Swanston Chris
Published: November 2020

Climate change is a growing concern for forests across Minnesota. Foresters, land managers, and landowners are considering how to prepare for future conditions and how to evaluate risks for particular sites. This field guide is designed as a quick reference on climate change for northern Minnesota forests. The intent is to highlight key information that can be used during field visits or forest planning. We hope that this guide will help foresters consider climate change risks together with local site characteristics, and also that it will help people design adaptation actions that help meet management goals.
Farming the floodplain: overcoming tradeoffs to achieve good river governance in New England
Authors: Warner Benjamin , Schattman Rachel
Published: November 2020

The goal of this case is for students to learn through the development of a sustainable river governance plan for Massachusetts focused on balancing needs and perspectives on local agriculture, flood resilience, and healthy ecosystems in the context of climate change. This will be challenging. Ideally, a river governance plan developed by the students would support local agriculture, increase flood resilience, and promote environmental stewardship. A role-playing exercise is included in this case that involves representatives of several stakeholders groups (personas assumed by a subset of students); these include a farmer, a fisher/recreationalist, a state river manager, an environmentalist, and a resident. The students will learn about the goals of a stakeholder to discuss with the others, negotiate with them, find ways to resolve conflicts and finally to create a governance plan.