bluuebunny/crossref_metadata_2025 huggingface dataset:
Endocrine Hypertension: The Urgent Need for Greater Global Awareness
Authors: Fernandez Cornelius J ,   Department of Endocrinology and Metabolism, Pilgrim Hospital, United Lincolnshire Hospitals NHS Trust, Boston, UK, Nagendra Lakshmi ,   Department of Endocrinology, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, India, Alkhalifah Mohammed ,   Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS Trust, Preston, UK,   Department of Family Medicine & Diabetes, King Saud University Medical City, Riyad, Saudi Arabia, Pappachan Joseph M ,   Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS Trust, Preston, UK,   Faculty of Science, Manchester Metropolitan University, Manchester, UK,   Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
Published: November 2023

Hypertension affects about 1.28 billion adults globally, and significantly increases the risk of chronic morbidity and mortality among sufferers. About 15% of these individuals have secondary hypertension, the majority of whom have dysfunction of one or more endocrine systems as the cause of hypertension. Although adrenal disorders are often identified as the cause of endocrine hypertension, extra-adrenal disease and pituitary disorders also can cause the disease. Timely diagnosis is of paramount importance, because of the potential for a surgical cure or optimal disease control with pharmacotherapy to prevent hypertensive complications. Even with its relatively high prevalence compared with many other chronic illnesses, the diagnosis of endocrine hypertension is often delayed or never made because of poor awareness about the disease among physicians. This review attempts to provide an overview of the disease, with some practical aspects of diagnosis and management of a few of the important disorders causing endocrine hypertension.
Metabolic Dysfunction-associated Fatty Liver Disease: An Urgent Call for Global Action
Authors: Fernandez Cornelius J ,   Department of Endocrinology & Metabolism, Pilgrim Hospital, United Lincolnshire Hospitals NHS Trust, Boston, UK, Nagendra Lakshmi ,   Department of Endocrinology, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, India, Pappachan Joseph M ,   Department of Endocrinology & Metabolism, Lancashire Teaching Hospitals NHS Trust, Preston, UK,   Faculty of Science, Manchester Metropolitan University, Manchester, UK,   Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
Published: November 2023

There has been an exponential increase in the global prevalence of fatty liver disease in recent years in association with the obesity pandemic worldwide. 'Metabolic dysfunction-associated fatty liver disease', the new terminology adopted by an international panel of experts in 2020 to largely replace the old term 'non-alcoholic fatty liver disease', has now been accepted by most hepatologists and diabetologists across the globe. The term metabolic dysfunction-associated fatty liver disease was created to better reflect the metabolicand liver-specific manifestations and complications of fatty liver disease. It is important to disseminate our current understanding of this enigmatic disease among the global scientific fraternity. Recent publications, including articles from the latest issue ofEndocrinology & Metabolism Clinics of North America, are attempting to fill this knowledge gap.
Challenges in Risk Stratification of Solid Atypical Mixed Echogenicity Thyroid Nodules
Authors: Valenzuela-Scheker Evana ,   Department of Endocrine Surgery, Memorial Healthcare System, Hollywood, FL, USA, Bimston David N ,   Department of Endocrine Surgery, Memorial Healthcare System, Hollywood, FL, USA, Golingan Hubert ,   Department of Internal Medicine, Mount Sinai Hospital, Miami Beach, FL, USA, Golding Allan ,   Department of Endocrine Surgery, Memorial Healthcare System, Hollywood, FL, USA, Harrell R Mack ,   Department of Endocrine Surgery, Memorial Healthcare System, Hollywood, FL, USA
Published: November 2023

Background: To determine the prevalence and risk of malignancy (ROM) in solid atypical mixed echogenicity thyroid nodules (SAMENs) with sonographic patterns not classifiable by the 2015 American Thyroid Association Ultrasound Risk Stratification System (NC ATA). Methods: We searched our prospectively collected endocrine surgery thyroid nodule (TN) database, with particular attention to those solid nodules that were NC ATA. An algorithm assigned each into one of the five ATA risk groups per the 2015 American Thyroid Association Ultrasound Risk Stratification System (ATA USRSS). TNs that the algorithm could not assign to a risk group were deemed NC ATA and were subsequently analyzed. Additionally, we categorized this group using an algorithm based on the 2017 American College of Radiology Thyroid Imaging Reporting and Data System (ACR-TIRADS). We were specifically interested in the characteristics that resulted in non-classification by the 2015 ATA USRSS and the fine needle aspiration biopsy (FNAB) cytology and surgical pathology results from the group. Results: We evaluated data from 5,040 nodules, of which 1,772 had surgical pathology. There were 150 solid nodules not classified by 2015 ATA USRSS, all of which demonstrated atypical features along with iso-, hetero-, hyper- and mixed echogenicity (solid atypical mixed echogenicity nodules- SAMENs). Sixty of these nodules were excised and sent for surgical pathology, while 90 were followed without surgical excision. Out of the 90 that did not undergo surgery, 82 underwent FNAB with cytologic evaluation. Of our 150 SAMENs, 40 were malignant by surgical histology and six were likely malignant by cytology (total SAMEN ROM without noninvasive follicular thyroid neoplasm with papillary-like nuclear features 31%). The most common sonographic pattern present in our SAMEN group consisted of an isoechoic solid component with microcalcifications (28/40–70% of all excised malignant nodules). In our excised malignant SAMENs, 50% demonstrated follicular-patterned neoplastic architecture while 48% displayed papillary architecture. Conclusion: Our study demonstrates that SAMENs with at least one suspicious sonographic feature: including (1) microcalcifications; (2) irregular or other suspicious margins,;opulation, and a higher ROM (31%) than the intermediate-risk group of the 2015 ATA USRSS (10–20%).
The impact of FDI on economic growth in developing countries: the role of FDI inflow and trade openness
Authors: Hai Minh, Vu Thi , Tuyet Trinh, Pham Thi
Published: November 2023

This study examines the relationship between foreign direct investment (FDI) inflow, trade openness, and the influence of FDI on economic growth. The threshold methodology and GMM estimation are employed to analyze panel data from 60 developing countries in the period between 1995 and 2019. This study demonstrates the positive impact of FDI on economic growth in developing countries. However, the study also finds a significant threshold of FDI inflow relative to GDP that changes the impact of inward FDI on GDP growth. Regarding the role of trade openness, a significant threshold is found, which also indicates the absorptive capacity of the host countries. Moving from below to above this threshold, an increase in FDI inflow leads to a lower increase in economic growth. An increase in FDI relative to GDP stimulates growth only when the host country has sufficient absorptive capacity with regard to trade openness above the threshold. We suggest developing countries tighten the coherence of trade liberalization and FDI attraction policies to obtain the benefits of FDI and make changes to attract new investors when they succeed in attracting massive FDI inflows.
The effect of the banking supervision on anti-money laundering
Authors: Benzerrouk Zakia Seid , Alnor Nasareldeen Hamed Ahmed , Al-Matari Ebrahim Mohammed , Alhebri Adeeb , Al-bukhrani Mohammed A
Published: November 2023

This article's goal is to investigate the connection between banking supervision (BakSup) and anti-money laundering (AnMeyLg). The study's hypothesized model was examined using a survey questionnaire research methodology. The Central Bank of Sudan and the compliance departments of Sudanese banks provided the information. Just 247 valid surveys were received out of a total distribution of 450 questionnaires. The partial least squares method for structural equation modeling was applied. The statistical findings supported the impact of banking supervision on anti-money laundering. In-depth discussions of the study's specifics and consequences were included at various points. There are several real-world applications of the findings of this study. Management can use the findings to guide their decisions on whether or not to establish anti-money laundering procedures in their banking firms. Banking supervision may provide managers with effective anti-money laundering strategies for maximizing bank performance and maintaining market share. This is one of the few empirical studies of its kind that looks at how banking supervision affects efforts to combat money laundering.
Association Of PTPN22 Gene Polymorphisms in Patients with Graves’ Disease in Iranian Papulation
Authors: Sadr Maryam , Esmaeili Samira , Amirzargar Somayeh , Rezaei Arezoo , Mohebbi Bahareh , Abrari Mina , Afradiasbagharani Parivash , Rezaei Nima , Amirzargar Ali Akbar
Published: November 2023

Background: Graves’ disease (GD) is an autoimmune disease that is associated with increased thyroid gland irritation and, consequently, hyperthyroidism. Autoimmune diseases are common in the general population and are influenced by genetic and environmental factors. PTPN22, which was reported as a susceptible locus for GD in several populations, acts as a negative regulator for activation of primary T-cells, and LYP polymorphism could potentially increase susceptibility to Graves' disease, which may play a role in other autoimmune conditions as well. In this study, we investigated the association of several PTPN22 single nucleotide polymorphisms (SNPs) with Graves patients.
Methods: After DNA extraction from peripheral blood cells, SNP Genotyping was performed through real-time PCR with allelic discrimination TaqMan genotyping assays (ABI Applied Biosystems, 7300 Real-Time PCR System, USA) based on manufacturer protocols. The frequencies of alleles and genotypes of PTPN22 SNPs (rs12760457, rs2476601, rs1310182, and rs1217414) were recorded.
Results: In our study, the rs1310182 was significantly more frequent in patients with GD than in healthy individuals. While the C allele of rs1310182 was 1.78 times more frequent in GD patients (95%CI: 1.18- 2.69, P=0.005), the T allele was more frequent in healthy subjects (OR=0.56, 95% CI: 0.37-0.84, P=0.005). In addition, the CC genotype of this SNP was 1.86 times more common in patients (P=0.05). No significant differences were observed between the other SNPs of this gene in case and control.
Conclusion: The results demonstrate that one SNP (rs1310182) of the PTPN22 gene is associated with susceptibility to GD in an Iranian population. Further studies, including functional analyses, are required.
The Story of Omicron: People, Scientists, and Global Communities
Authors: Rahmani Shayan , Nejadghaderi Seyed Aria
Published: November 2023

The Article Abstract is not available.
Dynamics of T-cell Responses Following COVID-19 mRNA Vaccination and Breakthrough Infection in Older Adults
Authors: Datwani Sneha , Kalikawe Rebecca , Mwimanzi Francis , Speckmaier Sarah , Liang Richard , Sang Yurou , Waterworth Rachel , Yaseen Fatima , Lapointe Hope , Barad Evan , DeMarco Mari , Holmes Daniel , Simons Janet , Montaner Julio , Romney Marc , Brumme Zabrina , Brockman Mark
Published: November 2023

Introduction: While older adults generally mount weaker antibody responses to a primary COVID-19 vaccine series, T-cell responses remain less well characterized in this population. We compared SARS-CoV-2 spike-specific T-cell responses after 2- and 3-dose COVID-19 mRNA vaccination and subsequent breakthrough infection in older and younger adults. Methods: We quantified CD4+ and CD8+ T-cells reactive to overlapping peptides spanning the ancestral SARS-CoV-2 spike protein in 40 older adults (median age 79) and 50 younger health care workers (median age 39), all COVID-19 naive, using an activation-induced marker assay. T-cell responses were further assessed in 24 participants, including 8 older adults, who subsequently experienced their first SARS-CoV-2 breakthrough infection. Results: A third COVID-19 mRNA vaccine dose significantly boosted spike-specific CD4+ and CD8+ T-cell frequencies to above 2-dose levels in older and younger adults. T-cell frequencies did not significantly differ between older and younger adults after either dose. Multivariable analyses adjusting for sociodemographic, health, and vaccine-related variables confirmed that older age was not associated with impaired cellular responses. Instead, the strongest predictors of CD4+ and CD8+ T-cell frequencies post-third-dose were their corresponding post-second-dose frequencies. Breakthrough infection significantly increased both CD4+ and CD8+ T-cell frequencies, to comparable levels in older and younger adults. Exploratory analyses revealed an association between HLA-A*02:03 and higher post-vaccination CD8+ T-cell frequencies, which may be attributable to numerous strong-binding HLA-A*02:03-specific CD8+ T-cell epitopes in the spike protein. Conclusion: Older adults mount robust T-cell responses to 2- and 3-dose COVID-19 mRNA vaccination, which are further boosted following breakthrough infection.
South Africa’s interest rate behaviour: Investigating the influence of the indicators of financial openness
Authors: Chile Nzeh, Innocent , Ogomegbunam Okolie David , Ibekwe Okolie Jonathan , Chinedu Izuogu Augustine
Published: November 2023

This study seeks to investigate the influence of financial openness variables on South Africa’s interest rate during the period between1980-2020. The study used both Augmented Dickey-Fuller (ADF) and Philip-Perron (PP) tests to determine the order of integration of the variables, while the autoregressive distributed lag (ARDL) bounds test was used to investigate both the short and long-run impact of the independent variables on the dependent variable. The findings of the study revealed that in the short-run both foreign direct investment (FDI) inflows and FDI outflows impacted the interest rate positively. However, portfolio investment, exchange rate and capital account openness did not have any significant impact on interest rate within the duration of this research. The long-run results revealed that FDI inflows had a positive and significant impact on interest rate. Also, while capital account openness had a significant and positive impact on the interest rate, FDI outflows, portfolio investment, and the exchange rate had no significant impact on interest rate. The study concludes that apart from portfolio investment which did not exert significant impact on interest rate, other financial openness indicators used in the study had a significant impact on South Africa’s domestic interest rate. The paper argues that, appropriate monetary policy measures targeted to lessen the monetary impact of excess capital inflows should be considered.  Additionally, capital account liberalization policy should be encouraged, but it needs to be regulated if it places an excessive amount of liquidity pressure on the economy.
ANALISIS FAKTOR ETIKA DI KELAS PADA SISWA ILMU PENGETAHUAN ALAM MAN KOTA PALANGKARAYA
Authors: Hartati Zainap , Amina Ikramina Yusti , Sueb Sueb
Published: November 2023

Etika memiliki hubungan antara sikap dan karakter dalam norma di masyarakat. Ilmu kesusilaan dan perilaku baik mulai pudar diterapkan saat pandemi, termasuk di lingkungan sekolah. Pembelajaran full online membuat kurangnya interaksi sosial langsung antara guru dengan siswa, sehingga pemahaman etika yang baik di kelas menurun. Penelitian bertujuan: 1) mendeskripsikan faktor etika di kelas IPA; 2) mendeskripsikan perbedaan tingkat faktor etika antara laki-laki dan perempuan; 3) mengetahui demografi etika siswa dikelas berdasarkan gender; 4) mendeskripsikan demografi siswa berdasarkan distribusi umur. Jenis penelitian deskriptif kuantitatif dan inferensial dengan data kuesioner etika dan referensi hasil studi kepustakaan. Pengumpulan data melalui kuesioner online. Teknik pengambilan sampel sampling purposive berdasar kriteria, maka sampel 120 siswa. Data dianalisis menggunakan perhitungan rerata, simpangan baku, dan Uji-T. Hasil penelitian: 1) faktor etika di kelas bagi siswa perempuan hanya memenuhi 6 indikator dan laki-laki  4 indikator (kategori sangat setuju); 2) adanya perbedaan faktor etika antara perempuan dan laki-laki; 3) demografi siswa berdasarkan gender di kelas IPA dan jenjang kelas X, XI, dan XII menunjukkan jumlah siswa perempuan > laki-laki; 4) demografi etika pada siswa berdasarkan distribusi umur tiap jenjang yang berbeda. Simpulan: pemahaman etika bagi siswa perempuan dan laki-laki tidak menunjukkan perbedaan yang signifikan dari pembelajaran online saat pandemi, namun demografi berdasarkan umur dapat mempengaruhi sikap dan moral.
PENGEMBANGAN E-MODUL FITOKIMIA LAHAN BASAH BERBASIS STEAM-INKUIRI UNTUK AKSELERASI KEMAMPUAN PEMECAHAN MASALAH DAN LITERASI SAINS MAHASISWA
Authors: Syahmani Syahmani , Iriani Rilia , Leny Leny , Saadi Parham , Prasetyo Yogo Dwi , Mustarianti Lila , Hayati Farida , Febrianti Shabrina Adzhani
Published: November 2023

Penelitian ini bertujuan untuk mengembangkan  bahan ajar (e-modul) fitokimia lahan basah berbasis STEAM-Inkuiri yang valid, praktis dan efektif. Model pengembangan dalam penelitian ini menggunakan ADDIE. Penelitian dilakukan pada mahasiswa pendidikan kimia yang mengambil mata kuliah fitokimia. Teknik pengumpulan data yang digunakan berupa lembar validasi, angket dan tes penilaian. Hasil penelitian menunjukkan bahwa (1) validitas e-modul yang dikembangkan dalam kriteria ini sangat valid, (2) kepraktisan dan keterbacaan, dan respon mahasiswa terhadap e-modul yang dikembangkan dalam kriteria sangat praktis, (3) efektivitas dilihat dari n-gain kemampuan pemecahan masalah, literasi sains, dan pemahaman konsep mahasiswa secara berurutan 0,49; 0,68; 0,59 berada pada kriteria sedang dan diperkuat dengan hasil uji Wilcoxon(p value < 0,05) yang menunjukkan ada peningkatan yang signifikan antara hasil pre-test dan post-test. Disimpulkan bahwa e-modul yang dikembangkan valid, praktis dan efektif sehingga layak untuk meningkatkan kemampuan pemecahan masalah, literasi sains dan pemahaman konsep mahasiswa.
PENGEMBANGAN INSTRUMEN TES BERBASIS KEMAMPUAN BERPIKIR KRITIS BERLANDASKAN LITERASI SAINS PADA MATERI PENCEMARAN LINGKUNGAN
Authors: Siagian Gunaria , Gunawan Revi Gina , Festiyed Festiyed , Ahda Yuni , Yerimades Yerimades
Published: November 2023

Tujuan dari penelitian ini adalah untuk mengetahui kelayakan instrumen tes berbasis kemampuan berpikir kritis berlandaskan literasi sains pada materi pencemaran lingkungan dengan melihat aspek validitas, reliabilitas, tingkat kesukaran, daya beda, dan uji respon pada mahasiswa.  Penelitian ini merupakan penelitian pengembangan dengan Analysis, Design, Development, Implementatiom, and Evaluation (ADDIE). Data penelitian ini diperoleh dengan mengujicobakan instrumen tes biologi yang dikembangkan berlandaskan literasi sains berupa tes essay sebanyak 20 soal. Analisis validasi isi menunjukkan bahwa sebanyak 17 soal valid. Reliabilitas instrumen 0,78, tingkat kesukaran 0,30-0,72 dan daya beda 0,04-0,72. Hasil uji respon diketahui 75% responden yang menyatakan sangat setuju dengan instrumen tes jenis ini. Berdasarkan kriteria tersebut, maka 14 soal telah dinyatakan baik dan layak digunakan sebagai instrumen tes biologi untuk melatih keterampilan berpikir kritis bagi mahasiswa. Intrumen tes yang dikembangkan telah masuk dalam kategori layak atau baik digunakan sebagai instrumen tes yang dapat melatih keterampilan berpikir kritis. Intrumen tes ini telah memenuhi kriteria validitas ahli dengan presentase 85% soal valid dan 15% soal tidak valid, reliabilitas 0,78 pada kategori tinggi, tingkat kesukaran 0,30 sampai 0,72, dan daya beda 0,04 sampai 0,72. Intrumen tes yang dikembangkan juga telah mendapat respon dengan presentase 75% pada kategori sangat baik dari responden.
BATIK TULUNGAGUNG: KAJIAN ETNOSAINS BERMUATAN NILAI KARAKTER UNTUK MENYONGSONG INDONESIA EMAS 2045
Authors: Anissa Desi Dwi , Silfianah Ifah
Published: November 2023

Pembelajaran sains perlu dikaitkan dengan budaya. Upaya tersebut dimulai dengan mengkaji etnosains pada batik Tulungagung sebagai penanaman nilai karakter dan pengetahuan konsep IPA. Oleh karena itu, dibutuhkan penanaman nilai karakter yang dikorelasikan dengan etnosains batik Tulungagung. Penelitian ini bertujuan untuk menganalisis dan mengkaji nilai karakter yang terdapat dalam batik Tulungagung baik dalam segi motif, warna maupun proses pembuatannya serta mengkorelasikan dengan etnosains batik. Metode penelitian ini adalah deskriptif kualitatif, metode pengumpulan data dengan observasi, wawancara dan dokumentasi di UD Batik Satrio Manah Tulungagung serta studi pustaka. Hasil penelitian ini menunjukkan bahwa batik pada proses pembuatannya memiliki keterkaitan dengan etnosains, etnobiologi yaitu flora dan fauna, etnokimia pada pewarnaan terkait dengan konsentasi zat, sedangkan pada etnofisika yaitu perubahan wujud dari padat ke cair. Sedangkan dari segi batik tulis memberikan nilai karakter yaitu kerja keras dan ulet, batik cap memberikan nilai karakter yaitu teliti, cermat dan kreatif, motif flora dan fauna memuat nilai karakter peduli terhadap lingkungan khususnya pada flora dan fauna, motif kendang dan Wayang Krisna yang memuat nilai karakter jujur, konsisten, adil, bijaksana. Berdasarkan konsep etnosains yang dapat diambil yaitu pada pewarnaan batik. Nilai karakter tersebut dapat ditanamkan melalui pembelajaran etnosains sebagai bentuk upaya memberikan edukasi pada generasi muda untuk menyongsong Indonesia Emas 2045.
KONSEPSI PESERTA DIDIK MELALUI TES DIAGNOSTIK TWO TIER DALAM PEMBELAJARAN KIMIA
Authors: Santoso Tri , Ahmar Dewi Satria , Afadil Afadil , Magfirah Magfirah , Sukmawati Sukmawati
Published: November 2023

Penelitian ini bertujuan untuk menganalisis konsepsi peserta didik pada materi hidrokarbon. Penelitian ini merupakan penelitian deskriptif yang mendeskripsikan konsepsi peserta didik yang meliputi pemahaman konsep, miskonsepsi, dan tidak paham konsep. Populasi dalam penelitian ini berjumlah 112 siswa yang berasal dari 2 sekolah SMA yakni SMAN 1 Balaesang dan SMAN 2 Balaesang yang berlokasi di Kecamatan Balaesang Kabupaten Donggala, Provinsi Sulawesi Tengah. Pengambilan sampel menggunakan teknik sampling jenuh sehingga seluruh populasi menjadi sampel penelitian. Instrumen yang digunakan adalah tes diagnostik two tier dengan nilai validitas sebesar 0,88 dan nilai reliabilitas sebesar 0,77 dan wawancara. Hasil penelitian menunjukkan bahwa konsepsi peserta didik di SMAN 1 Balaesang untuk kategori paham konsep sebesar 64,4%, untuk kategori miskonsepsi sebesar 23,4%, dan untuk kategori tidak paham konsep sebesar 12,2%. Konsepsi peserta didik di SMAN 2 Balaesang untuk kategori paham konsep sebesar 59,9%, kategori miskonsepsi sebesar 26,1%, dan kategori tidak paham konsep sebesar 13,9%.
PENGEMBANGAN E-LKPD BERBASIS LIVEWORKSHEET UNTUK MENINGKATKAN CREATIVE THINKING SKILL SISWA SMP PADA MATERI PENCEMARAN LINGKUNGAN
Authors: Nirmala Rizka , Wahyuni Sri , Ridlo Zainur Rasyid
Published: November 2023

Creative thinking skill menjadi suatu hal yang penting pada pembelajaran IPA  untuk menghadapi tuntutan abad ke-21. Faktanya keterampilan peserta didik dalam keterampilan berpikir kreatif masih rendah. Rendahnya creative thinking skill salah satunya disebabkan oleh perangkat pembelajaran yang digunakan belum dapat membuat siswa untuk berpikir secara kreatif. Pengembangan E-LKPD berbasis liveworksheet ini mengacu pada penelitian yang telah dilaksanakan oleh Simanjuntak (2021) yang menunjukkan bahwa siswa terlihat lebih aktif dalam pelaksanaan pembelajaran dan sebagian sudah dapat mengungkapkan gagasan, sehingga mampu meningkatkan creative thinking skillnya. Meskipun E-LKPD berbasis liveworksheet sudah diteliti berpengaruh dalam meningkatkan creative thinking skill peserta didik, namun belum terdapat penelitian yang membahas keefektifan E-LKPD berbasis liveworksheet pada pembelajaran IPA. Tujuan penelitian ini untuk mengetahui kevalidan, kepraktisan dan keefektifan pengembangan E-LKPD menggunakan website liveworksheet. Kegiatan penelitian dilakukan di SMPN 1 Jember pada siswa kelas VII I dengan, metode yang digunakan adalah R&D yang merujuk dengan model ADDIE.. Hasil penelitian menunjukkan media yang dikembangkan telah memenuhi kriteria sebagai berikut: (1) sangat valid berdasarkan uji kelayakan oleh kelompok ahli yang mendapatkan presentase rata-rata sebesar 88%; (2) Praktis, berdasarkan lembar keterlaksanaan yang disi oleh tiga observer yang mendapatkan presentase rata-rata sebesar 90%; (3) peningkatan keterampilan berpikir kreatif memperoleh nilai N-gain sebesar 0,72 dengan kriteria tinggi dan angket respon yang diperoleh sebesar 87%.
MODUL DIGITAL MULTIMODAL: INSERSI KEARIFAN LOKAL TANAMAN PURUN PADA MATERI TERMOKIMIA TERINTEGRASI NILAI RELIGIUS
Authors: Rizkiana Fitria , Prasiska Emilda , Khairunnisa Yasmine
Published: November 2023

Kurikulum adalah alat untuk mencapai tujuan pendidikan. Dalam implementasinya, ada beberapa aspek yang harus diperhatikan diantaranya peningkatkan kualitas keimanan dan ketaqwaan, akhlakul karimah serta ragam dan potensi daerah peserta didik. Oleh sebab itu, diperlukan bahan ajar yang sesuai untuk mendukung terlaksananya kurikulum tersebut. Penelitian ini bertujuan untuk menentukan validitas dan  mengukur respon peserta didik terhadap modul digital multimodal pada materi termokimia terintegrasi nilai religius dan kearifan lokal tanaman purun. Guna menjawab tujuan penelitian tersebut, peneliti menggunakan metode penelitian dan pengembangan (R & D) dengan model Borg & Gall termodifikasi, yang terdiri atas 6 tahapan yaitu: penelitian pendahuluan, perencanaan, pengembangan produk, validasi produk, revisi produk, dan ujicoba lapangan. Teknik pengumpulan data adalah teknik non tes berupa angket. Instrumen penelitian yang digunakan adalah angket validasi modul dan angket respon. Subjek penelitian adalah peserta didik kelas XI IPA MAN 2 Barito Kuala tahun pelajaran 2021/2022 sebanyak 15 orang dan 3 ahli (1 dosen program studi kimia UPR serta 2 guru kimia dari MAS Raudhatsyuyuban dan MAN 2 Barito Kuala). Data yang diperoleh dari peserta didik diolah dengan teknik persentase dan dikategorikan sesuai kriteria respon yang telah ditentukan, sedangkan data yang diperoleh dari ahli dihitung indeks kesepakatannya menggunakan indeks Aiken, untuk kemudian dikategorikan berdasarkan indeks V yang diperoleh. Hasil studi menunjukkan bahwa indeks kesepakatan yang diberikan oleh para ahli berada pada kategori sangat valid dan mendapat respon yang sangat baik dari 15 peserta didik sebagai pengguna. Berdasarkan hasil yang diperoleh dapat disimpulkan bahwa modul ini dapat digunakan sebagai bahan ajar pada materi termokimia.
A formação de professoras(es) para atuação na Educação Infantil e Anos Iniciais do Ensino Fundamental no Curso de Pedagogia da Universidade de Brasília frente à Resolução CNE/CP nº 2/2019
Authors: Almeida Lorrany Martins de , Macedo Aldenora Conceição de , Devechi Catia Piccolo Viero
Published: November 2023

O artigo apresenta considerações de docentes do curso de Pedagogia da Universidade de Brasília (UnB) em relação à formação da professora e do professor para atuação na Educação Infantil e Anos Iniciais do Ensino Fundamental diante das mudanças educacionais determinadas pelo Conselho Nacional de Educação (CNE) no curso de Pedagogia, por meio da Resolução CNE/CP nº 2/2019, que revoga a CNE/CP nº 2/2015. Tem como base o estudo do Projeto Político-Pedagógico (PPPC) do curso de Pedagogia Diurno da Faculdade de Educação (FE) e dos resultados obtidos em dois questionários aplicados ao seu corpo docente e a integrantes do Núcleo Docente Estruturante (NDE). Ao todo, foram 32 respostas, dentre as quais destacamos a existência de entendimentos diferentes. Enquanto há docentes que defendem o modelo de formação para uma ampla atuação, conforme Resolução CNE/CP nº 1/2006, outras(os) entendem que o curso deveria ter um foco mais específico na formação para a atuação na Educação Infantil e nos Anos Iniciais do Ensino Fundamental. Conclui que, embora o PPPC defina o objetivo formativo do curso, não há consenso docente acerca dos propósitos da formação, o que pode impactar diretamente na profissionalização da professora ou professor que atuará nessas etapas do ensino.
Dinamika Personalisasi Partai Politik Dalam Rekrutmen Bakal Calon Walikota Solo 2020 (Studi Kasus Partai Demokrasi Indonesia Perjuangan (PDI-P)
Authors: Ridwan Mochamad Atami , Fatkhuri Fatkhuri
Published: November 2023

Penelitian ini bertujuan untuk menjelaskan tentang adanya dinamika yang terjadi di dalam proses rekrutmen bakal calon Walikota Solo pada pilkada serentak 2020. Dinamika tersebut dipengaruhi adannya personalisasi di internal partai yang ditandai dengan dominasi ketua umum serta lemahnya organisasi partai. Metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif dengan menggunakan data primer serta sekunder diantaranya berupa wawancara, dokumentasi, dan studi pustaka. Hasil yang diperoleh dari penelitian ini menunjukkan bahwa terdapat dinamika di dalam fungsi rekrutmen bakal calon Walikota Solo diantaranya terdapat intervensi dari Ketua Umum Partai akibat dari dominasinya yang begitu kuat di dalam partai politik sehingga struktur partai di tingkat lokal yaitu DPC PDI-P Kota Surakarta tidak dapat menerapkan skema bottom-up dengan mengusung calon berdasarkan hasil penjaringan. Lemahnya kelembagaan partai juga terlihat dari peraturan partai tentang rekrutmen kepala daerah yang tidak diimplementasikan dengan baik, tidak tercermin prinsip demokrasi di internal partai, ketidakmandirian struktur partai di tingkat lokal, hingga sifat pragmatisme partai dengan mengusung calon walikota solo berdasarkan latar belakang sosial calon tersebut yang merupakan putra Putra Presiden Joko Widodo yang sedang menjabat saat ini.
Vehicle state and parameter estimation based on adaptive anti-outlier unscented Kalman filter and GA-BPNN method
Authors: Liu Yingjie , Cui Dawei , Peng Wen
Published: November 2023

A multi-machine-learning improved adaptive Kalman filtering method is proposed to address the problem of handling abnormal data encountered in the vehicle state estimation. Firstly, the unscented Kalman filter (UKF) algorithm is improved by introducing a BP neural network improved by the genetic algorithm (GA-BPNN) to regulate and correct the global error of the UKF method. Then, the anti-outlier technique is applied to fully eliminate isolated and speckled outliers in the measurement, achieving further improvement on GA-BPNN-UKF and significantly improving the robustness of the filtering process. Finally, a simulation is applied to verify the effectiveness of the proposed new algorithm, and then its results are analyzed to obtain a firm substantiation of its effectiveness for further practical applications. The simulation results indicate that the estimation performance of the GA-BPNN algorithm is significantly better than that of Extended Kalman filter (EKF) method.
OPINIONS OF TURKISH SOCIETY ON PHYSIOTHERAPIST CONSULTANCY FOR MATTRESS SELECTION: A QUALITATIVE FOCUS GROUP STUDY
Authors: Türkmen Ceyhun , Düger Tülin
Published: November 2023

Purpose: Numerous mattress manufacturers market their products as "orthopedic" with therapeutic capabilities, claiming that the right mattress can improve an individual's sleep and quality of life. In this qualitative focus group study, we aimed to investigate how customers see the mattress brand that provides physiotherapist support services and their experiences with mattress companies with different characteristics.
Methods: Fifty participants were selected from women between the ages of 20 and 60 who were married or in preparation for marriage, and who had purchased a mattress or were in the research phase. The group discussion rules were determined and shared separately in all five groups. The data were thematically analyzed using the framework analysis approach.
Results: Customers' perceptions about mattress brands and their thoughts on physiotherapist consultancy are understood by questions such as "what do you think about mattress brands?" and "what does physiotherapist consultancy for mattress selection mean to you?" These two themes will be presented and discussed.
Conclusion: The physiotherapist consultancy was a service to satisfy consumer needs in terms of trust. An innovative service has been offered that can persuade the consumer to switch to the new and unknown New Brand. However, it is also possible that advertisements with health content, as previously experienced with other brands, have a negative effect on brand perception. For this reason, it may be more beneficial for the brand if physiotherapists who will work in the field act as life coaches rather than health professionals.
influence of brand image, service quality, and individual characteristics on loyalty with taxpayer satisfaction as an intervening variable at tax service offices in Palembang City
Authors: Akbar Atmaja , Andriana Isni , Maulana Ahmad , Widiyanti Marlina
Published: November 2023

This study investigates the influence of brand image, service quality, and individual characteristics on loyalty, with taxpayer satisfaction as an intervening variable at Tax Service Offices in Palembang City. Data were collected by distributing questionnaires to 100 taxpayers registered at three Tax Service Offices in Palembang City. The analytical technique employed was multiple linear regression with path analysis. The results indicate that individual characteristics significantly impact satisfaction and loyalty. However, variables such as brand image and service quality do not significantly influence satisfaction and loyalty. Additionally, taxpayer satisfaction does not significantly influence loyalty itself. Furthermore, brand image, service quality, and individual characteristics do not significantly influence loyalty when taxpayer satisfaction is considered an intervening variable. This research will reference future studies using variables in similar research contexts.
Factors Influencing the Participation of Small-Scale Fishermen in Marine Protected Areas in East Java
Authors:   Faculty of Fisheries and Marine Sciences, Universitas Brawijaya, Indonesia, Efani Anthon , Manzilati Asfi ,   Faculty of Economics and Business, Universitas Brawijaya, Indonesia, Riza Muhammad Faisal ,   Faculty of Administrative Sciences, Universitas Brawijaya, Indonesia
Published: November 2023

Marine Protected Areas (MPA) were created to address overfishing, which can harm fishing communities and reduce the number of fish. This affects how much food is available and how happy people feel, especially for people who work as small-scale fishermen. They depend on catching fish to meet their needs. This study aimed to find out what factors affect fishermen's choice to participate in MPAs. It was done in Malang and Probolinggo Regencies in East Java, with 200 fishermen involved in the research. This research gathers information by asking people questions through a survey. The survey has a set of questions that are planned. The economist studies the probit model to determine what factors affect fishermen's choice to join MPAs. The findings indicated that factors like family members, marital status, number of fishing gear, market access, and savings did not have a noteworthy impact on the involvement of small-scale fishermen in MPAs. But, things like how old they are, how much education they have, whether they belong to a fishermen's group, if they work outside of fishing, and if they are part of a cooperative all greatly impact whether small fishermen participate in MPAs.
The Role of “Ikan Makan” and “Ikan Tacucu” to Overcome the Financial Insecurity of Purse Seine Crews Households in Maluku
Authors:   Faculty of Fisheries and Marine Science, Pattimura University, Apituley Yolanda Marla Tania Nangkah , Hahury Hendri D ,   Faculty of Economics and Business, Pattimura University, Camerling Billy J ,   Faculty of Engineering, Pattimura University, Wenno Max Robinson , Bawole Dionisius ,   Faculty of Fisheries and Marine Science, Pattimura University
Published: November 2023

“Ikan makan” and “ikan tacucu” are the terms found in purse seine fishing systems in Maluku which is one of the important sources in the economic sustainability of fishermen crews’ households. This study aims to: 1) Describe the meaning and function of “ikan makan” and “ikan tacucu” in the context of purse seine fisheries in Maluku, 2) Analyze the importance of “ikan makan” and “ikan tacucu” in improving the economy of purse seine crews households, and 3) Analyze the importance of “ikan makan” and “ikan tacucu” in overcoming the financial insecurity for purse seine crews households. This research was conducted by using a survey method. Data were analyzed by using qualitative and quantitative descriptive analysis. The results show that there are two patterns of the distribution of “ikan makan”; first share the fish equally among the all crews and then each of them is responsible for it; second, selling all the “ikan makan” and the money will be divided equally among all crew members. The income of the crews from the sale of “ikan makan” in fish season is IDR 69,000 – 166,000/trip and in no fish season fish IDR 44,000 – 111,000/trip. Income from the sale of “ikan makan” during the fish season and no fish season are not able to overcome the households financial insecurity and only to reduce or suppress it.
Machine Learning Model for Predicting Mortality Risk in Patients With Complex Chronic Conditions: Retrospective Analysis
Authors: Hernández Guillamet Guillem , Morancho Pallaruelo Ariadna Ning , Miró Mezquita Laura , Miralles Ramón , Mas Miquel Àngel , Ulldemolins Papaseit María José , Estrada Cuxart Oriol , López Seguí Francesc
Published: November 2023

Background

The health care system is undergoing a shift toward a more patient-centered approach for individuals with chronic and complex conditions, which presents a series of challenges, such as predicting hospital needs and optimizing resources. At the same time, the exponential increase in health data availability has made it possible to apply advanced statistics and artificial intelligence techniques to develop decision-support systems and improve resource planning, diagnosis, and patient screening. These methods are key to automating the analysis of large volumes of medical data and reducing professional workloads.

Objective

This article aims to present a machine learning model and a case study in a cohort of patients with highly complex conditions. The object was to predict mortality within the following 4 years and early mortality over 6 months following diagnosis. The method used easily accessible variables and health care resource utilization information.

Methods

A classification algorithm was selected among 6 models implemented and evaluated using a stratified cross-validation strategy with k=10 and a 70/30 train-test split. The evaluation metrics used included accuracy, recall, precision, F1-score, and area under the receiver operating characteristic (AUROC) curve.

Results

The model predicted patient death with an 87% accuracy, recall of 87%, precision of 82%, F1-score of 84%, and area under the curve (AUC) of 0.88 using the best model, the Extreme Gradient Boosting (XGBoost) classifier. The results were worse when predicting premature deaths (following 6 months) with an 83% accuracy (recall=55%, precision=64% F1-score=57%, and AUC=0.88) using the Gradient Boosting (GRBoost) classifier.

Conclusions

This study showcases encouraging outcomes in forecasting mortality among patients with intricate and persistent health conditions. The employed variables are conveniently accessible, and the incorporation of health care resource utilization information of the patient, which has not been employed by current state-of-the-art approaches, displays promising predictive power. The proposed prediction model is designed to efficiently identify cases that need customized care and proactively anticipate the demand for critical resources by health care providers.
Research on World Consciousness in Guo Moruo’s Poetry
Authors: Xun Ye , Han Li
Published: November 2023

This article starts from the world trend of thought absorbed by Guo Moruo, sorts out Guo Moruo’s world consciousness and the dynamic process of his acceptance of world trends, and explores the reasons why these advanced trends of thought were applied by Guo Moruo in combination with Guo Moruo’s life experience and spiritual life. Finally, the authors return to Guo Moruo’s poetry works and analyze how these ideological currents have brought about some important changes in his poetry creation, leading to some of his poetry works presenting new characteristics and becoming a revolutionary milestone in the history of literature.
FUNCTIONAL OUTCOME OF PATIENTS WITH CHRONIC PLANTAR FASCIITIS TREATED BY LOCAL INJECTION OF AUTOLOGOUS PLATELET-RICH PLASMA
Authors: RAJESH KUMAR KANOJI  , PRADEEP KUMAR SUTHAR  , HIMANSHU
Published: November 2023

Objectives: The objectives of the study are as follows: To assess functional outcome of patients with chronic plantar fasciitis (PF) treated by autologous injection of platelet-rich plasma (PRP). (1) To know the side effects, if any, in these patients.
Methods: This was a prospective study conducted in the Department of orthopedics of a tertiary care medical college. Forty patients having chronic PF were included in this study on the basis of a predefined inclusion and exclusion criteria. Autologous PRP was injected in plantar fascia at the point of maximum tenderness. Patients were followed up for 3 months. Intensity of pain and functional outcome was assessed using the visual analog score (VAS) score and American Orthopedic Foot and Ankle Score (AOFAS) score. For statistical purposes, p<0.05 was taken as significant.
Results: There were 14 (35.00%) males and 26 (65.00%) females with a M: F ratio of 1:1.85. The mean age of male and female patients was found to be 43.82±9.98 years and 41.68±10.12 years, respectively. Majority of the patients (65%) were overweight whereas 6 (15%) patients were obese and 8 (20%) patients were having a normal healthy body mass index. The mean duration of symptoms was found to be 10.67±3.89 months. The mean VAS score at the time of final follow-up was significantly less (0.96±0.46) as compared to pre-injection VAS score (7.20±1.38) whereas the AOFAS score at the time of final follow-up (91.9±6.68) significantly improved as compared to pre-injection AOFAS score (38.96±8.78). There were no major side effects in any of the studied cases.
Conclusion: Local injection of autologous PRP appears to be an effective treatment for chronic PF in terms of reduction of pain and functional improvement with no significant side effects.
IOT E-Circular Notification for Students Using a WIFI-Based LED Advertising Board
Authors: Kota Haripal Reddy
Published: November 2023

Abstract: Scrolling display board is a common sight today. Advertisement is going digital. The use of led scrolling display board at big shops, shopping centers, railway station, bus stands and educational institutes is becoming an effective mode of communication in providing information to the people as notice board. But these off-the-shelf units are somewhat inflexible in terms of updating the message instantly. If the user wants to change the message it needs to be done using a computer and hence the person needs to be present at the location of the display board. It means the message cannot be changed from wherever or whenever. Also the display board cannot be placed anywhere because of complex and delicate wiring. 'GSM based LED Scrolling Display Board' is a model for displaying notices/messages at places that require real-time noticing, by sending messages in the form of SMS through mobile[1-3]. It is a system wherein the display board need not be reprogrammed to display a new message because it is wireless. The project aims to develop a moving sign board which empowers the user to change the scrolling message using application in our mobile phone service instantaneously unlike a desk bound device such as PC or laptop. The user can update it even from a Wi-Fi distant. The system can be edited any time anywhere within the Wi- Fi range[4].
Restoration of Obscured Images
Authors: Senkamalavalli Dr. R.
Published: November 2023

Abstract: For the aim of exploring the deep undersea world map, a picture of high quality without interfering objects is preferred. However, within the water, the image quality tends to be hampered by light scattering, water density, and light attenuation. effects. Besides, the dynamic interference may affect the important underwater map. during this paper, we proposed a multi-step and all-around underwater image processing system, especially for the underwater images taken in succession to enhance the image quality, remove the dynamic interference, and reconstruct the image. The first step involves utilizing the dark channel approach together with the improved gray world algorithm for brightness adaptation and color correction. Initially, it identifies and removes a dynamic interference regarding image enhancement. Secondly, we applied an upgraded total variation model to patch the blank at the value of resolution. Finally, the super-resolution of the small print is realized by applying an improved BP network. After simulation and experiments, our system proved to realize ideal results of image enhancement and reconstruction.
Early Detection and Treatment of Posterior Crossbites in Interceptive Orthodontics: A Review
Authors: Mohideen Ayesha
Published: November 2023

Abstract: Posterior crossbites represent a common malocclusion in orthodontics that, if left untreated, can lead to various dental and skeletal complications. This review article aims to provide a comprehensive overview of the early detection and treatment of posterior crossbites in interceptive orthodontics. By examining the current literature and clinical practices, we highlight the importance of early intervention, various diagnostic methods, and treatment modalities available to manage posterior crossbites effectively.