bluuebunny/crossref_metadata_2025 huggingface dataset:
As matrizes culturais da Rádio Rebelde Zapatista e a busca por uma comunicação autônoma
Authors: Costa Filho Ismar Capistrano , Salgueiro Marques Ângela Cristina
Published: October 2021

A construção autonomia, entendida como autodefinição identitária, autogoverno comunitário e autoconsumo produtivo, é uma das preocupações fundamentais do movimento zapatista que ampliou suas formas de comunicação e diálogo de modo tal que não se resume ao EZLN e às comunidades autônomas, mas envolve a articulação com vários atores aderentes. O objetivo principal deste artigo é refletir sobre as contribuições da Rádio Rebelde, localizada na região de Los Altos no Estado de Chiapas, para esta construção da autonomia zapatista. Pretendemos apontar algumas das matrizes culturais presentes nos endereçamentos utilizados nas emissões radiofônicas para construir imaginários que nos possibilitam compreender o sentido de autonomia e articulações comunicativas que podem estar presentes na programação da emissora.
Influence of noise and sampling rate on the discrete image representation error
Authors: Timofeev Alexander , Sultanov Albert
Published: October 2021

Introduction: Digital registration of images is accompanied not only by an error caused by finite spatial resolution of the photo matrix, but also by the effect of noise whose contribution to the total error decreases with an increase in the aperture of the photosensors in the matrix. Thus, changing the sampling rate has the opposite effect on the sampling error and on the error caused by the noise. Purpose: Finding the optimal image sampling rate which would provide the minimum sampling error in the presence of noise.  Results: We have studied how an image discrete representation error depends on the sampling frequency and noise level. The image sampling process in the presence of noise was simulated in the MATLAB environment. The dependencies of the root-mean-square deviation of the sampling error caused by spectrum truncation (decrease in the passband of the low-pass filter) and the noise component of the error on the sampling frequency were plotted. A theorem is formulated on the upper bound of the sampling theorem: when sampling a function of finite duration in the presence of noise, there is a finite minimum value of the sampling error which is determined by the shape of the spectrum of the function and the noise level. Practical relevance: It is advisable to use the research results when choosing a photomatrix by the number of pixels for recording images in the presence of noise, as well as when choosing a low-pass filter passband for primary processing of a digital image.
From Engel to Enactivism
Authors: Aftab Awais , Nielsen Kristopher
Published: October 2021

In this article we offer a two-part commentary on Bolton and Gillett’s reconceptualization of Engel’s biopsychosocial model. In the first section we present a conceptual and historical assessment of the biopsychosocial model that differs from the analysis by Bolton and Gillett. Specifically, we point out that Engel in his vision of the biopsychosocial model was less concerned with the ontological possibility and nature of psychosocial causes, and more concerned with psychosocial influences in the form of illness interpretation and presentation, sick role, seeking or rejection of care, the doctor-patient therapeutic relationship, and role of personality factors and family relationships in recovery from illness, etc. On the basis of this assessment, we then question Bolton and Gillett’s restricted focus on accounting for biopsychosocial causal interactions. The second section compares Bolton and Gillett’s account with a recent enactivist account of mental disorder that tackles similar conceptual problems of causal interactions. Bolton and Gillett’s utilize elements of the 4E cognition, but they combine these proto-ideas with an information-processing paradigm. Given their explicit endorsement of 4E approaches to mind and cognition, we illustrate some key ways in which a more fleshed out enactive account, particularly one that doesn’t rely on notions of information-processing, differs from the account proposed by Bolton and Gillett.
Adversarial Leadership in the Data Era
Authors: Graham David
Published: October 2021

The world has changed significantly since the day I was born.  One could argue that its fantastic political, moral, philosophical, and environmental gyrations have led to an inevitable collision between what is absolute and that which is not.  Added to this widening gyre is the fundamental role of data and information in seating emperors on their respective thrones.  The shift of power away from the halls of legislature and the proletariat into the hands of the emerging data bourgeoisie has led to the need for a new type of leadership, focused on using the prevalence of data in adversarial ways to shape society (and indeed the world) in new ways.
Hipocalcemia e cetose - principais doenças metabólicas da vaca leiteira durante o período de transição - uma revisão de literatura
Authors:   Centro Universitário Nossa Senhora do Patrocínio, Proto Mylena Garcia , Barros Milena Cristina Bernardo de ,   Centro Universitário Nossa Senhora do Patrocínio, Barbosa Bruna Stanigher ,   Centro Universitário Nossa Senhora do Patrocínio
Published: October 2021

With the increased production demand in the dairy industry comes the need to keep animals healthier, thus avoiding large economic losses due to low productivity. During the transition period, dairy cows are susceptible to the onset of infectious diseases and metabolic imbalances due to the big change in their diet, it could be poor in needed nutrients to maintain the animal's body score, with this, the dry matter intake decreases up to 40% while energy expenditure increases due to milk and colostrum production, getting into a negative energy balance state.
Pneumothorax in COVID-19 – A New Challenge
Authors: Bhandari Sudhir , Rankawat Govind , Singh Ajeet
Published: October 2021

Background: Coronavirus disease 2019 mainly affect the lungs which can complicate into pneumothorax and require hospitalization. We aimed to discuss the presence of pneumothorax and its possible risk factors in vulnerable patients of COVID-19 to establish an effective preventive and therapeutic strategy for this fatal complication.

Methods: This retrospective observational study included 30 admitted patients of COVID-19 associated pneumothorax. The patient’s data concerning demography, clinical manifestation, associated medical illness, point of onset of pneumothorax, mode of oxygenation with FiO2 and PEEP, radiological imaging, and outcome were extracted from their medical records. All collected data were tabulated, compiled, and analyzed to establish possible causality of pneumothorax.

Results: All patients of the study group exhibited symptomatic presentations, 73% of patients had severe clinical conditions and 24 patients also had associated chronic medical illness. In our study pneumothorax developed 3rd week onwards after symptoms onset with a mean time of pneumothorax was found to be 23.96 days (23.96±8.06). At the point of diagnosis of pneumothorax, 22 patients were on non-invasive ventilation, 6 on high flow mask, and 2 patients on invasive ventilation, these patients required higher FiO2 (77.66%) and higher PEEP (10.83 cmH2O) to maintain PaO2 within normal range. All patients had raised COVID-related inflammatory markers viz. NLR, D-dimer, CRP, IL-6, and these markers showed a positive correlation with the duration of hospital stay in patients of pneumothorax.

Conclusion: Pneumothorax can be suspected in COVID-19 infected patients having severe COVID-19 pneumonia of longer duration with assistant ventilation and raised inflammatory markers going to rapid worsening of symptoms.
LAPROSCOPIC COMMON BILE DUCT EXPLORATION: STENT DRAINAGE VERSUS T- TUBE DRAINAGE
Authors: Kumar Gulshan
Published: October 2021

Introduction: One of the safe & feasible methods for the management of extra-hepatic bile duct calculi is laparoscopic bile duct exploration. Around 10-15% of the subjects who have surgery due to gallstone disease have choledocholithiasis associated with it. A standard procedure to prevent bile escape from the choledochotomy site is conventionally postoperative T-tube drainage following common bile duct exploration. 

Aims & Objectives: Comparative study of laproscopic common bile duct exploration using stent drainage versus t- tube drainage.

Material & Methods: The study involved a total of 46 subjects with choledocholithiasis, who were categoryed in 2 categorys. Category I as a drainage category of stents and Category 2 as a drainage category of T-tubes. The subjects in both classes underwent LCBDE surgery. Of the 46 subjects operated, 23 were in category I (stent drainage category) and 23 were in category 2 (T-tube drainage category). 

Results:  23 subjects were categoryed in the stent drainage and T-tube drainage categories, respectively. In both classes, no perioperative or postoperative mortality was reported. Subjects had hypertension in stent drainage category 4 (17.39 percent) and 5 (21.73 percent) suffered from diabetes as a comorbid disease, while 2 (8.69 percent) subjects had jaundice. Four (17.39 percent) subjects with diabetes and three (13.04 percent) subjects with jaundice were found in T-tube drainage category 3 (13.04 percent) with hypertension. In both classes, no statistically significant difference was found. In terms of organisational results and outcomes, statistically significant variations were found in both categorys (Table 3). Mean operating time was 103± 22.4 in category I while 127±32.7 (P value < 0.005) in category II. In the Stent Drainage Category, blood loss during procedure was 22±3.7 ml, while in the T-tube drainage category it was 38±5.1 (P value < 0.005).

Conclusion. After laparoscopic choledochotomy, primary closure of the bile duct with spontaneously reversible biliary stent placement is a viable and practicable process. With spontaneously removable biliary stents, less surgery time, less bleeding and less intestinal complications have been observed.

Keywords: stent drainage, T- tube drainage, choledochotomy
ДОСЛІДЖЕННЯ СФОРМОВАНОСТІ ПОКАЗНИКІВ ПСИХІЧНОГО ЗДОРОВ’Я ДОШКІЛЬНИКІВ З ІНТЕЛЕКТУАЛЬНИМИ ПОРУШЕННЯМИ
Authors: БОРЯК Оксана , ЧОБАНЯН Анна
Published: October 2021

Авторками статті на основі порівняльного аналізу даних за результатами емпіричного дослідження виявле- но специфіку сформованості показників психічного здоров’я старших дошкільників розумовою відсталістю, що конкретизується в низькому рівні сформованості обох критеріїв (соціально-особистісного/емоційно-поведінко- вого). У межах статті конкретизовано, що становлення психічного здоров’я на тлі розумової відсталості дітей дошкільного віку зумовлено низьким рівнем усвідомлення дитиною себе як члена соціальної групи, несформованою здатністю сприймати та продукувати інформацію про себе, свої вподобання, значущих дорослих, неспромож- ністю дотримання соціальних норм та цінностей у поведінці, високому рівні тривожності, наявних агресив- них тенденцій, відсутності самостійності й безпорадності щодо надання допомоги іншим, очікуванні допомоги з боку дорослих, неадекватності емоційно-бурхливих реакцій, що супроводжуються частими змінами настрою, прагненнями до усамітнення. Дослідниці висувають припущення про переважання постнатального періоду розвитку, як першочергового фактора впливу на становлення психічного здоров’я дошкільника. В цьому аспекті актуальності набуває підви- щення виховного потенціалу матері (батьків/осіб, що їх заміщують) на потребу формування/розвитку визначе- них показників психічного здоров’я розумово відсталих дітей. Отримані результати підтверджують зумовленість виникнення розумової відсталості негативними чинни- ками пренатального, натального та постнатального етапів розвитку. Важливо саме у дошкільному віці пра- вильно діагностувати існуючі прояви порушень показників психічного здоров’я, для впровадження відповідних заходів для їх виправлення та розвитку. Подальші дослідження повинні визначити взаємодію інтелектуальних порушень до виявлених підвищених показників порушень психічного здоров’я.
ТЕНДЕНЦІЇ РОЗВИТКУ ІНКЛЮЗИВНОЇ ОСВІТИ ПІД ЧАС ВИВЧЕННЯ ХІМІЇ В УМОВАХ ДИСТАНЦІЙНОГО НАВЧАННЯ В ЗАКЛАДАХ ЗАГАЛЬНОЇ СЕРЕДНЬОЇ ОСВІТИ
Authors: ЄСІКОВА Ірина
Published: October 2021

У статті висвітлено тенденції розвитку інклюзивної освіти під час вивчення хімії в умовах дистанційно- го навчання. Розглянуто поняття «віртуальна лабораторія», охарактеризовано види віртуальних засобів, що надають можливість всім учасникам навчального процесу, незалежно від фізичних можливостей робити хімічні експерименти та актуальність їх застосування в інклюзивному середовищі закладів загальної середньої освіти. Мета статті полягає в аналізі віртуальних хімічних лабораторій та їх можливостей, перевірці їх ефектив- ності під час навчання дітей з особливими освітніми потребами. Проаналізовано літературні джерела із вико- ристання віртуального хімічного експерименту на уроках хімії під час навчання дітей з особливими потребами. На основі досліджень визначено переваги та недоліки використання віртуальних лабораторій, їх позитивний вплив на процес навчання дітей з особливими потребами. Здійснено огляд сучасних віртуальних хімічних засобів навчання котрі доцільно використовувати в інклю- зивному середовищі під час вивчення хімії. Наведено приклади віртуальних хімічних лабораторій, котрі визнані в Україні та за її межами, а саме: ChemCollective, phet.colorado.edu, Chemist Free- Virtual Chem Lab, VirtuLab. Описано їх функціональні можливості та методику застосування як спеціально розроблених програмних засобів, для застосування в освітніх цілях в інклюзивному середовищі закладів загальної середньої освіти. Встановлено, що віртуальні хімічні лабораторії дають змогу виконувати хімічний експеримент всім, неза- лежно від фізичних особливостей учнів. Надають можливість учням котрі були відсутні на занятті виконувати досліди, забезпечують індивідуальний темп виконання досліду та мотивують до засвоєння нового матеріалу шляхом роботи в віртуальному середовищі. Отже, проведення хімічних експериментів за допомогою віртуальних лабораторій дозволяє ефективно вирі- шити низку навчальних задач таких як безпечність для здоров’я учнів, фінансова недоступність та можливість навчатися та виконувати досліди в період пандемії та дистанційного навчання. Вказано перспективні напрями продовження дослідження.
Utjecaj vremena uzimanja reznica i različite koncentracije fitohormona IBA na ožiljavanje feijoe Feijoa sellowiana (O. Berg.) O. Berg
Authors: Paladin Soče Ivana
Published: October 2021

Feijoa Feijoa Sellowiana (O.Berg.) Burret je suptropska voćka iz porodice Myrtaceae. Uzgaja se širom svijeta, a u Hrvatskoj je brojčano najmanje zastupljena vrsta voćke. Feijoa se uglavnom razmnožava generativno. U Zavodu za mediteranske kulture dosadašnja iskustva razmnožavanja feijoe pomoću reznica nisu dala najbolje rezultate. Stoga, cilj ovog rada je utvrditi ukorjenjivanje reznica Feijoe tretiranim različitim koncentracijama fitohormona indol-maslačne kiseline (IBA) s obzirom na vrijeme uzimanja reznica. Istraživanje je trajalo dvije godine, a korištene su poludrvenaste i drvenaste reznice čiji je bazalni dio tretiran različitim koncentracijama fitohormona IBA (1500, 2000, 2500, 3000 ppm). Najuspješnije se pokazao fitohormon koncentracije 2500 ppm-a kod poluzrelih reznica s postotkom od 32% ožiljenih reznica.
Effect of biostimulant on yield characters of common bean cultivars under Southwestern Goiás conditions
Authors: Carvalho Ivan Ricardo , Ferreira Luiz Leonardo Ferreira , Conte Giordano Gelain , Amaral Gileade Costa Leonel , Campos Juliana Naves , Tomazele Augusto Antonio Souza , Carrijo Núbia Sousa , Pereira Valúcia Teodoro , Souza Adriano Teixeira , Loro Murilo Vieira
Published: October 2021

This study aimed to evaluate the effect of biostimulant positioning on common bean cultivars in the southwestern Goiás conditions. The experiment was conducted in the municipality of Mineiros-GO. The experimental design was a randomized block in factorial 6x3, corresponding to the positioning of the Triplus® biostimulator (R5, R5 + R8 and water) in six common bean cultivars (BRS Campeiro, BRS Esteio, BRS Estilo, BRS Marfim, BRS Notavel and BRS Perola) in 4 replicates. The following productive attributes were evaluated: number of pod, number total of grains, number of commercial grains, number of non-commercial grains, mass of commercial grains, thousand grains mass. There was a significant interaction between cultivar x biostimulant as well as the factors alone. At the end of the experiment, it was concluded that the positioning of the biostimulant via foliar in the R5 phenological phase provided the highest yields for all common bean cultivars, especially BRS Estilo (43.87 sc ha-1) and BRS Notavel (43.02 sc ha-1).  Biostimulant applications at stage R5 promoted the best results for number of non-commercial grains, mass of commercial grains, thousand grains mass. In the three stratifications used in the dendrogram, it was possible to form two groups of genotypes. Number total of grains, number of commercial grains and number of pod positively correlate with yield.
Australian Paediatric Surveillance Unit (APSU) Annual Surveillance Report 2020
Authors: Teutsch Suzy M , Nunez Carlos A , Morris Anne , Eslick Guy D , Khandaker Gulam , Berkhout Angela , Novakovic Daniel , Brotherton Julia M , McGregor Skye , King Jonathan , Egilmezer Ece , Booy Robert , Jones Cheryl A , Rawlinson William , Thorley Bruce , Elliott Elizabeth J
Published: October 2021

For 27 years, national prospective data on selected rare childhood diseases have been collected monthly by the Australian Paediatric Surveillance Unit (APSU) from paediatricians and other clinical specialists who report cases in children aged up to 16 years. We report here the annual results of APSU surveillance in 2020 for ten rare communicable diseases and complications of communicable diseases, namely: acute flaccid paralysis (AFP); congenital cytomegalovirus (CMV) infection; neonatal herpes simplex virus (HSV) infection; perinatal exposure to human immunodeficiency virus (HIV); paediatric HIV infection; severe complications of seasonal influenza; juvenile onset recurrent respiratory papillomatosis (JoRRP); congenital rubella syndrome; congenital varicella syndrome; and neonatal varicella infection. We describe the results for each disease in the context of the total period of study, including demographics, clinical characteristics, treatment and short-term outcomes. Despite challenges presented by the coronavirus disease 2019 (COVID-19) pandemic in 2020, more than 1,400 paediatricians reported regularly to the APSU and an overall monthly reporting rate of > 90% was achieved. The minimum AFP target of 1 case per 100,000 children aged less than 15 years was achieved and there were few cases of vaccine-preventable diseases (JoRRP, rubella, varicella). However, high cases of congenital CMV, neonatal HSV and perinatal exposure to HIV persist. There were no severe complications of seasonal influenza reported for the first time in 13 years. This is consistent with other surveillance data reporting a decline of influenza and other communicable diseases in 2020, and likely reflects the wider effects of public health measures to reduce transmission of SARS-CoV-2 in the Australian community.
ESTABLISHMENT OF LUCERNE IN PUMICE SOILS
Authors: Parle J.N.
Published: October 2021

In some areas of the droughty pumice soils of the central North Island considerable difficulties have been experienced in attempts to grow lucerne, especially in the Reporoa and Galatea districts and to a less extent at Taupo. The work described in this paper was carried out at Galatea on an area of low fertility with no history of topdressing.
FORMULATION OF A RATlONAL FERTILISER PROGRAMME IN TUSSOCK COUNTRY
Authors: Ludecke T.E.
Published: October 2021

New Zealand agriculture is primarily dependent on the growth of high-producing pastures which rely on legumes for their nitrogen supply. Legumes under favourable conditions are able to. fix large amounts of nitrogen through nodule bacteria attached to their roots. Nitrogen is supplied to grasses by underground transference after the needs of the host plant are satisfied, and is also provided from the urine and dung of grazing animals. Almost invariably, poor pasture growth in New Zealand is the result of low legume production. Contributing factors to this are a poor supply of available phosphorus, sulphur, molybdenum, and potassium, ineffective nodulation, and acid soil conditions.
GRASSLAND CHANGES AND PROGRESS IN TARANAKI SINCE 1951
Authors: Moss G.R.
Published: October 2021

Since our last conference held here in 1951 there has been a steady increase in production throughout Taranaki, but there have been, no spectacular changes in grassland farming
EFEKTIFITAS PENGGUNAAN HANDPHONE DALAM MENINGKATKAN MINAT BERKONSULTASI SISWA SMP (STUDI KASUS DI SMP NEGERI 2 BELO)
Authors: Khairunnisa Khairunnisa
Published: October 2021

The implementation of guidance and counseling services  should take place in comfortable and conducive conditions. Guidance and counseling is expected to develop one's potential and competence in the community to be able to fulfill their duties optimally. In addition, in helping individuals overcome various problems that can interfere with its development[1]. This research is motivated by many students who feel afraid when called by counseling and guididance teachers, let alone have to come to the counseling room to consult or sharing probem. The lack of interest in consulting students was allegedly due to various factors. One of them is due to the lack of socialization conducted by counseling and guidance teachers in introducing what and how counseling and guidance is. If this socialization can be carried out well, it will at least give a clear picture to students that the counseling and guidance is present as a forum and student's friend while studying. Efforts that can be done include: Able to familiarize yourself with students and be able to position yourself as friends, and improve counseling skills so as to improve verbal and non verbal communication skills, express problems, understand problems and accept students. So that these efforts are maximized, the counseling and guidance teacher can use the media as a tool, one of which can be through the help of media, namely mobile phones. To get rid of these feelings, the BK teacher uses mobile media as a communication tool to consult with students. This study aims to determine whether the use of mobile phones is effective in increasing the interest in consulting students of STATE 2ND JUNIOR HIGH SCHOOL. The approach used in this study is qualitative research that is shown to describe and describe existing phenomena that are scientific[2]. While the type of research used is descriptive research. This research was conducted in SMP NEGERI 2 BELO, the research subjects were 2 counseling and guidance teachers and 5 students who had used mobile phones in consulting services. The method of data collection is done by observation, interviews, and documentation. Analysis of data using qualitative descriptive by interpreting the data obtained. The research shows that the process of using mobile phones in increasing the interest in consulting students of SMP NEGERI 2 BELO is carried out in stages, starting from the preparation stage consisting of media and socialization selection, then the implementation stage consists of identification, giving outreach and evaluating both the process and the results. Based on the results of the study, the researchers can conclude that the use of mobile phones is effective in increasing the interest in consulting students of SMP Negeri 2 BELO
Efektivitas Model Experiential Learning Untuk Meningkatkan Keterampilan Mengelola Emosi Marah
Authors: Nurhayati Nurhayati , - Faijin , - Amiruddin , Indah Sulistia
Published: October 2021

Rasa  marah  merupakan  bagian  dari  emosi  yang  dimiliki  oleh semua individu, dalam kadar tertentu hampir setiap individu pernah mengalaminya. Terkadang individu sulit untuk mengontrol emosi marah, hal  itu  tergantung  dari  keterampilan  individu  dalam  mengelola  emosi marah yang muncul, oleh karena itu, guru BK perlu memberikan latihan agar peserta didik memiliki keterampilan dalam mengelola emosi marah melalui teknik tertentu. Tujuan penelitian untuk mengetahui keefektifan model experiential learning untuk melatih keterampilan pengelolaan emosi marah. Rancangan penelitian ini menggunakan True Experimental Pre-test, Posttest Control Group Design. Populasi penelitian adalah peserta didik SMP  Negeri  6  Kota  Bima  kelas  VII.  Subjek penelitian  terjaring  secara random sehingga diperoleh sejumlah 10 orang yang dibagi ke dalam kelompok eksperimen (n = 5) dan kelompok kontrol (n = 5). Instrumen lain yang  digunakan  adalah  lembar  penilaian  diri,  lembar  tugas  mengelola emosi marah dan pedoman observasi. Teknik statistik yang digunakan untuk menguji  hipotesis  adalah  Two  Independent  Sample  Test  Mann  Whitney untuk membandingkan perbedaan skor keterampilan pengelolaan emosi marah antara kelompok eksperimen dan kelompok kontrol. Hasil analisis menunjukkan bahwa nilai koefisien Z (-2.207) dengan signifikansi sebesar 0.027 yang berarti 0.027 di bawah nilai probabilitas yaitu (0.027 < 0.05). Berdasarkan hasil uji statistik tersebut dapat disimpulkan bahwa H0 ditolak yang berarti ada perbedaan yang signifikan antara peserta didik yang diintervensi dengan model experiential learning dan peserta didik yang diintervensi dengan bimbingan secara umum, sehingga model experiential learning efektif untuk meningkatkan keterampilan pengelolaan emosi marah peserta didik SMP. Hasil pelatihan menunjukan bahwa model experiential learning bisa untuk mengajarkan keterampilan mengelola emosi marah peserta didik SMP
Pengaruh Peer Group Terhadap Motivasi Belajar Siswa SMP Negeri 8 Kota Bima
Authors: Amin Nur Syariful , Khairunnisa Khairunnisa , Indah Sulistia
Published: October 2021

Peer group adalah sekelompok teman sebaya yang mempunyai ikatan emosional yang kuat dan mereka dapat berinteraksi, bergaul, bertukar pikiran, dan pengalaman dalam memberikan perubahan dan pengembangan dalam kehidupan sosial dan pribadi anggota.Sedangkan motivasi pada dasarnya dapat membantu dalam memahami dan menjelaskan perilaku individu termasuk perilaku individu yang sedang belajar. Penelitian ini ditujukan untuk mengetahui pengaruh peer group terhadap motivasi belajar siswa.
Penelitian ini dilakukan di SMP Negeri 8 Kota Bima . Subyek dalam penelitian ini yaitu seluruh siswa kelas VIII yang tergabung dalam 8 peer group dengan jumlah 31 orang siswa. Penelitian ini termasuk penelitian kuantitatif karena menggunakan rancangan empiris dan gejala yang diamati telah ada secara wajar tampa harus memanipulasi terlebih dahulu. Instrumen pengumpulan data dalam penelitian ini adalah observasi, angket dan dokumentasi. Angket dianalisa dengan menggunakan analisis statistik deskriptif  melalui rumus korelasi product moment. Dari hasil analisis data kualitatif diketahui bahwa nilai korelasi product moment (r) adalah 0,43 (43%). Sehingga dengan menggunakan kaidah pengambilan keputusan dalam uji statistik maka dapat disimpulkan bahwa hipotesis alternatif (Ha) yang berbunyi : ada pengaruh peer group terhadap motivasi belajar siswa di SMPN 8 Kota Bima, dapat diterima
Upaya peningkatan hasil belajar kognitif melalui pembelajaran berbasis praktikum ditinjau dari kemampuan akademik mahasiswa
Authors: Fahruddin Fahruddin , Bakhtiar Bakhtiar
Published: October 2021

Jenis penelitian ini adalah penelitian tindakan kelas (PTK). Adapun rancangan penelitiannya yaitu melalui empat tahap dari setiap siklus yaitu dimulai tahap perencanaan, pelaksanaan, observasi/evaluasi, dan refleksi. Penelitian ini bertujuan untuk mengetahui: 1) Peningkatan hasil belajar kognitif melalui pembelajaran berbasis praktikum pada mahasiswa pendidikan Biologi tahun akademik 2017/2018. 2) Peningkatan hasil belajar kognitif ditinjau dari kemampuan akademik mahasiswa. Subyek penelitian adalah seluruh mahasiswa semester IV kelas A yang berjumlah 30 orang. Instrumen penelitian ini adalah berupa soal tes dengan bentuk soal pilihan ganda, yang terdiri dari 20 soal. Penelitian ini dihtung berdasarkan rumus ketuntasan individu dan klasikal, kemudian dilanjutkan dengan uji N-Gain. Berdasarkan hasil perhitungan dengan menggunakan rumus Ketuntasan Individu dan Ketuntasan Klasikal, maka proses pembelajaran siklus II mencapai peningkatan dengan 29 orang berkategori tuntas, dan dinyatakan tuntas secara klasikal dengan perolehan nilai sebesar 96,66%, maka diperoleh kesimpulan bahwa hasil penelitian menunjukkan: 1) Ada peningkatan hasil belajar kognitif melalui pembelajaran berbasis praktikum. 2) Ada peningkatan hasil belajar kognitif ditinjau dari kemampuan akademik mahasiswa melalui pembelajaran berbasis praktikum dengan persentase mahasiswa berkemampuan tinggi sebesar 46,67%, sedang sebesar 43,33%, dan rendah sebesar 10%. Menurut hasil uji N-Gain 46,67% berkategori tinggi, dan 53,33% berkategori sedang, yang berarti peningkatan hasil belajar kognitif sangat baik
PENGARUH PEMBERIAN PUPUPK HAYATI DAUN KERSEN TERHADAP PERTMBUHAN TANAMAN TOMAT (Solanum lyicopersicum L)
Authors: Azmin Nikman Nikman , Hartati Hartati , Bakhtiar Bakhtiar
Published: October 2021

Tanaman tomat (Solanun lycopersicum L) merupakan tanaman holtikultura yang banyak dikembangkan oleh para petani, selain itu tanaman tomat  kaya akan nutrisi dan paling banyak digemari dan dikonsumsi serta semakin tingginya permintaan pasar sehingga banyak orang yang bembudidayakan tanaman tomat, namun pada kenyataanya tomat yang dibudidayakan di Indonesia umumnya hanya digunakan satu jenis pupuk saja. Dalam rangka meningkatkan proses pertumbuhan tomat, maka diperlukan rekayasa edafik yaitu dengan Pemberian Pupuk Hayati dari Daun Kersen. Tujuan penelitian ini untuk mengetahui pertumbuhana tanaman tomat dengan pemberian berbagai dosis pupuk hayati daun kersen yang tepat, diharapkan dapat mendukung keberhasilan tumbuhan. Penelitian ini dapat dilakukan pada Februari sampai Mei 2020. Rancangan  penelitian yang digunakan adalah Rancangan acak kelompok (RAK) dengan 5 perlakuan dan 3 ulangan untuk masing-masing perlakuan, sehingga terdapat 15 kombinasi percobaan. Sampel yang digunakan dalam penelitian ini adalah 150 benih tanaman tomat. Dengan parameter yang diteliti adalah tinggi tanaman, jumlah daun, jumlah cabang. Hasil penelitian menunjukan bahwa pemberian pupuk hayati dari daun kersen dengan dosis yang berbeda terhadap pertumbuhan pada tanaman tomat berpengaruh secara signifikan. Pada tanaman terbaik diperoleh pada perlakuan P4 dosis pupuk 40cc/liter air dengan hasil tinggi tanaman pada umur 28 HST 153,33 cm dan jumlah daun terbanyak diperoleh pada perlakuan dosis 40cc/liter air dengan hasil rata-rata jumlah daun pada umur 28 HST adalah 63,3 Helai
HUBUNGAN ANTARA PENGETAHUAN PENCEMARAN LINGKUNGAN TERHADAP PARTISIPASI IBU RUMAH TANGGA DALAM MELINDUNGI LINGKUNGAN
Authors: Saifullah Saifullah
Published: October 2021

Penelitian adalah survey dengan pendekatan korelasional. Perolehan data primer dilapangan menggunakan kuesioner yang disusun berdasarkan indikator-indikator yang ada dalam masing-masing variabel penelitian. Tujuan penelitian ini adalah untuk mengetahui hubungan antara dua variabel independen dengan variabel dependen. Penelitian ini menggunakan metode survei, dengan 101 responden. Pengambilan sampel dilakukan dengan proportionate cluster / area random sampling. Lokasi Penelitian ini dilakukan di Bantaran Sungai Padolo Kelurahan Dara kecamatan Rasana’e Barat Kota Bima. Analisis data menggunakan korelasi dan regresi sederhana. Hasilnya menghasilkan dua kesimpulan; ada hubungan positif yang signifikan antara pengetahuan tentang pencemaran lingkungan terhadap partisipasi ibu rumah tangga dalam perlindungan Lingkungan.
THE ROLE OF PARENTS IN BOLO VILLAGE IN SUPPORTING DISTANCE LEARNING DURING THE COVID-19 PANDEMIC
Authors: Mawaddah Ida , Zulhafriliya Zulhafriliya , Sudarsono Sudarsono
Published: October 2021

The Indonesian government was concerned about the impact of a wider spread of Covid-19, so it moved quickly to break the chain of transmission by urging people to live a healthy lifestyle, avoid crowds, and keep a safe distance. As a result, the circumstance has a significant impact on education and learning. The goal of this study is to learn more about the role of parents in promoting distant learning and to identify the characteristics that encourage and limit distance learning in Bolo Village during the Covid-19 outbreak. Students are forced to study from home due to government regulations. Teachers can ensure students' learning activities in a variety of ways, one of which is by involving parents as the primary companion of students when they are at home. The participants in this study were parents and their junior high school-aged children. The information was gathered through organized interviews utilizing the researcher's prepared questions. The data in this study was analyzed utilizing qualitative data analysis approaches such as the Miles and Huberman model, which features a cycle that includes data reduction, data presentation, verification, and conclusion drafting. According to the findings of this study, parents in Bolo Village played four roles in supporting learning from home during the Covid-19 pandemic: 1) accompanying children in learning, 2) intense communication with children, 3) providing supervision to children, and 4) educating and supporting children motivation. The supporting variables discovered are: 1) responsibility, 2) family values, and 3) availability to satisfy the needs of children. There are also barriers, such as 1) internet network issues, 2) too much workload, and 3) boring and less diversified learning approaches.
TATA KELOLA DESA WISATA DI DESA NANGAMIRO KECAMATAN PEKAT KABUPATEN DOMPU
Authors: Yani Ahmad
Published: October 2021

Pariwisata adalah berbagai kegiatan wisata dan didukung oleh fasilitas dan layanan yang disediakan oleh masyarakat, pemerintah maupun pengusaha. Maka dalam penelitian ini bertujuan untuk mengetahui terkait tata kelolah pariwisata yang telah dilaksanakan. Metode yang digunakan dalam penelitian ini adalah metode kualitatif yang menjelaskan data secara deskriptif, dengan Teknik pengumpulan data yaitu wawancara, observasi dan dokumentasi. Sedangkan sumber data yang digunakan adalah data primer yang diperoleh dari lokasi penelitian berupa informan penelitian dan selanjutnya didukung oleh data sekunder berupa dokumen data. Hasil penelitian ini menunjukkan bahwa pengelolaan pariwisata di Desa Nangamiro Kecamatan Pekat kabupaten Dompu belum berjalan secara maksimal, ditinjau dari standar tata kelola pariwisata yang baik menurut Peraturan Menteri Dalam Negeri Nomor 10 Tahun 2009 tentang Kepariwisataan. Hal ini dikarenakan pencapaian setiap standar pengelolaan belum sepenuhnya terpenuhi. Faktor-faktor tersebut antara lain keaktifan dan sinergi stakeholders belum sepenuhnya terwujud, kemitraan hanya sampai di tingkat pemerintahan desa dan kemitraan belum dirasakan secara luas serta belum mampu mendorong kepemilikan daerah, program pelatihan yang belum dilaksanakan, masyarakat aspirasi masih umum, promosi masih minim dan berdiri sendiri-sendiri, serta pedoman pemantauan dan evaluasi tempat wisata masih sederhana tanpa ada indikator khusus untuk mengukur dampak kegiatan pariwisata yang dilakukan.
Production of Recombinant Horseradish Peroxidase in an Engineered Cell-free Protein Synthesis System
Authors: Park Yu-Jin , Kim Dong-Myung
Published: October 2021

One of the main advantages of a cell-free synthesis system is that the synthetic machinery of cells can be modularized and re-assembled for desired purposes. In this study, we attempted to combine the translational activity of Escherichia coli extract with a heme synthesis pathway for the functional production of horseradish peroxidase (HRP). We first optimized the reaction conditions and the sequence of template DNA to enhance protein expression and folding. The reaction mixture was then supplemented with 5-aminolevulinic acid synthase to facilitate co-synthesis of the heme prosthetic group from glucose. Combining the different synthetic modules required for protein synthesis and cofactor generation led to successful production of functional HRP in a cell-free synthesis system.
Real-Time Monitoring of Dissection Events of Single Budding Yeast in a Microfluidic Cell-Culturing Device Integrated With Electrical Impedance Biosensor
Authors: Zhu Zhen , Geng Yangye , Wang Yingying , Liu Ke , Yi Zhenxiang , Zhao Xiangwei , Ouyang Shuiping , Zheng Ke , Fan Yimin , Wang Zixin
Published: October 2021

Microfluidic devices in combination with fluorescent microscopy offer high-resolution and high-content platforms to study single-cell morphology, behavior and dynamic process in replicative aging of budding yeast, Saccharomyces cerevisiae. However, a huge mass of recorded images makes the data processing labor-intensive and time-consuming to determine yeast replicative lifespan (RLS), a primary criterion in yeast aging. To address this limitation and pursue label-free RLS assays, electrical impedance spectroscopy (EIS) that can be easily functionalized through microelectrodes in microfluidic devices, was introduced to monitor cell growth and division of budding yeast. Herein, a microfluidic device integrated with EIS biosensor was proposed to perform in-situ impedance measurement of yeast proliferation in single-cell resolution so as to identify the momentary events of daughter dissection from its mother. Single yeast cells were reliably immobilized at the bottleneck-like traps for continuous culturing, during which daughter cells were effectively detached from their mother cells by hydraulic shear forces. Time-lapse impedance measurement was performed every 2 min to monitor the cellular process including budding, division and dissection. By using the K-means clustering algorithm to analyze a self-defined parameter “Dissection Indicator,” to our knowledge for the first time, the momentary event of a daughter removing from its mother cell was accurately extracted from EIS signals. Thus, the identification of daughter dissection events based on impedance sensing technology has been validated. With further development, this microfluidic device integrated with electrical impedance biosensor holds promising applications in high-throughput, real-time and label-free analysis of budding yeast aging and RLS.
Pre-clinical Models of Metastasis in Pancreatic Cancer
Authors: Miquel Maria , Zhang Shuman , Pilarsky Christian
Published: October 2021

Pancreatic ductal adenocarcinoma (PDAC) is a hostile solid malignancy coupled with an extremely high mortality rate. Metastatic disease is already found in most patients at the time of diagnosis, resulting in a 5-year survival rate below 5%. Improved comprehension of the mechanisms leading to metastasis is pivotal for the development of new targeted therapies. A key field to be improved are modeling strategies applied in assessing cancer progression, since traditional platforms fail in recapitulating the complexity of PDAC. Consequently, there is a compelling demand for new preclinical models that mirror tumor progression incorporating the pressure of the immune system, tumor microenvironment, as well as molecular aspects of PDAC. We suggest the incorporation of 3D organoids derived from genetically engineered mouse models or patients as promising new tools capable to transform PDAC pre-clinical modeling and access new frontiers in personalized medicine.
Comprehensive Analysis of N6-Methyladenosine RNA Methylation Regulators Expression Identify Distinct Molecular Subtypes of Myocardial Infarction
Authors: Shi Xin , Cao Yaochen , Zhang Xiaobin , Gu Chang , Liang Feng , Xue Jieyuan , Ni Han-Wen , Wang Zi , Li Yi , Wang Xia , Cai Zhaohua , Hocher Berthold , Shen Ling-Hong , He Ben
Published: October 2021

Background: Myocardial infarction (MI) is one of the leading threats to human health. N6-methyladenosine (m6A) modification, as a pivotal regulator of messenger RNA stability, protein expression, and cellular processes, exhibits important roles in the development of cardiac remodeling and cardiomyocyte contractile function.

Methods: The expression levels of m6A regulators were analyzed using the GSE5406 database. We analyzed genome-wide association study data and single-cell sequencing data to confirm the functional importance of m6A regulators in MI. Three molecular subtypes with different clinical characteristics were established to tailor treatment strategies for patients with MI. We applied pathway analysis and differentially expressed gene (DEG) analysis to study the changes in gene expression and identified four common DEGs. Furthermore, we constructed the protein–protein interaction network and confirmed several hub genes in three clusters of MI. To lucubrate the potential functions, we performed a ClueGO analysis of these hub networks.

Results: In this study, we identified that the levels of FTO, YTHDF3, ZC3H13, and WTAP were dramatically differently expressed in MI tissues compared with controls. Bioinformatics analysis showed that DEGs in MI were significantly related to modulating calcium signaling and chemokine signaling, and m6A regulators were related to regulating glucose measurement and elevated blood glucose levels. Furthermore, genome-wide association study data analysis showed that WTAP single-nucleotide polymorphism was significantly related to the progression of MI. In addition, single-cell sequencing found that WTAP is widely expressed in the heart tissues. Moreover, we conducted consensus clustering for MI in view of the dysregulated m6A regulators’ expression in MI. According to the expression levels, we found MI patients could be clustered into three subtypes. Pathway analysis showed the DEGs among different clusters in MI were assigned to HIF-1, IL-17, MAPK, PI3K-Akt signaling pathways, etc. The module analysis detected several genes, including BAG2, BAG3, MMP2, etc. We also found that MI-related network was significantly related to positive and negative regulation of angiogenesis and response to heat. The hub networks in MI clusters were significantly related to antigen processing and ubiquitin-mediated proteolysis, RNA splicing, and stability, indicating that these processes may contribute to the development of MI.

Conclusion: Collectively, our study could provide more information for understanding the roles of m6A in MI, which may provide a novel insight into identifying biomarkers for MI treatment and diagnosis.
Green Synthesis of pH-Responsive, Self-Assembled, Novel Polysaccharide Composite Hydrogel and Its Application in Selective Capture of Cationic/Anionic Dyes
Authors: Srivastava Nandita , Roy Choudhury Anirban
Published: October 2021

Dyes are one of the most hazardous chemicals causing significant environmental pollution and affecting water quality. Majority of the existing methods for dye removal and degradation involve synthetic membranes and use of hazardous chemicals, further resulting in secondary pollution. The present study reports polysaccharide based novel composite hydrogel as biodegradable matrix for pH-responsive selective adsorption of cationic/anionic dyes. This membrane showed pH-responsive adsorption of methyl green (MG) and methyl orange (MO) with similar adsorption equilibrium, i.e., 315 and 276 mg g−1, respectively. Interestingly, selective adsorption at different pH has allowed separation of dye mixtures that holds incredible industrial importance for dyes recovery. The hydrogel matrix was able to completely separate MG, a model cationic dye at neutral pH from the dye mixture whereas, it was possible to remove 60% MO, a model anionic dye at acidic pH. Furthermore, comprehensive isothermal and kinetic studies of adsorption revealed that Freundlich isotherm describing the multilayer coverage and pseudo-second-order kinetics were followed. Thermodynamic studies indicated that the adsorption process was spontaneous and endothermic. In fact, the membrane was reusable for at least ten cycles and exhibited desorption efficiency of 80 and 60% for MO and MG, respectively, which may be further recycled to make the process environmentally sustainable. Overall, this study proposes an inexpensive, simple, biologically safe, and efficient adsorbent material for dye effluent treatment.
Genomic Determinants of Pathogenicity and Antimicrobial Resistance for 60 Global Listeria monocytogenes Isolates Responsible for Invasive Infections
Authors: Shi Dawei , Anwar Tanveer Muhammad , Pan Hang , Chai Wenqin , Xu Sihong , Yue Min
Published: October 2021

Listeria monocytogenes remains a significant public health threat, causing invasive listeriosis manifested as septicemia, meningitis, and abortion, with up to 30% of cases having a fatal outcome. Tracking the spread of invasive listeriosis requires an updated knowledge for virulence factors (VFs) and antimicrobial resistance features, which is an essential step toward its clinical diagnosis and treatment. Taking advantage of high-throughput genomic sequencing, we proposed that the differential genes based on the pathogenomic composition could be used to evaluate clinical observations and therapeutic options for listeriosis. Here, we performed the comparative genomic analysis of 60 strains from five continents with a diverse range of sources, representing serotypes 1/2a, 1/2b, 1/2c, and 4b, comprising lineage I and lineage II and including 13 newly contributed Chinese isolates from clinical cases. These strains were associated with globally distributed clonal groups linked with confirmed foodborne listeriosis outbreak and sporadic cases. We found that L. monocytogenes strains from clonal complex (CC) CC8, CC7, CC9, and CC415 carried most of the adherence and invasive genes. Conversely, CC1, CC2, CC4, and CC6 have the least number of adherence and invasive genes. Additionally, Listeria pathogenicity island-1 (LIPI-1), LIPI-2, intracellular survival, surface anchoring, and bile salt resistance genes were detected in all isolates. Importantly, LIPI-3 genes were harbored in CC3, CC224, and ST619 of the Chinese isolates and in CC1, CC4, and CC6 of other worldwide isolates. Notably, Chinese isolates belonging to CC14 carried antibiotic resistance genes (ARGs) against β-lactams (blaTEM-101, blaTEM-105) and macrolide (ermC-15), whereas CC7 and CC8 isolates harbored ARGs against aminoglycoside (aadA10_2, aadA6_1), which may pose a threat to therapeutic efficacy. Phylogenomic analysis showed that CC8, CC7, and CC5 of Chinese isolates, CC8 (Swiss and Italian isolates), and CC5 and CC7 (Canadian isolates) are closely clustered together and belonged to the same CC. Additionally, CC381 and CC29 of Chinese isolates shared the same genomic pattern as CC26 of Swiss isolate and CC37 of Canadian isolate, respectively, indicating strong phylogenomic relation between these isolates. Collectively, this study highlights considerable clonal diversity with well-recognized virulence and antimicrobial-resistant determinants among Chinese and worldwide isolates that stress to design improved strategies for clinical therapies.