bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Lama Penyimpanan Jamu Beras Kencur terhadap Pertumbuhan Kapang
Authors: Pinto Laksono Fransiskus Xaverius Agung , Dwiyanti Ratih Dewi , Rifqoh Rifqoh Rifqoh , Insana Aima
Published: June 2022

During the Covid-19 pandemic, people began to maintain their health, by using herbal medicine as an alternative treatment. One type of herbal medicine used is jamu beras kencur because it has properties to increase stamina, increase appetite, and relieve aches and cough disorders. In the Regulation of the Minister of Health of the Republic of Indonesia No. 007 of 2012 carrying herbs such as jamu beras kencur does not require marketing authorization. The quality of the herbal medicine produced has not been confirmed as feasible from microbial contamination, especially in molds, the number of yeast molds in the jamu beras kencur must comply with BPOM standards Number 32 of 2019 namely AKK 103 colonies/mL. This study aimed to determine the effect of the storage time of jamu beras kencur on mold growth with storage treatments of 0 hours, 4 hours, 8 hours, 12 hours, and 24 hours at room temperature. This type of research is a Quasi Experiment with a research design of One Group Pretest-Postest Design. The results of this study showed that the average AKK value was 0 hours 0.2x100 colonies/mL, 4 hours 0.4x100 colonies/mL, 8 hours 0.4x100 colonies/mL. 12 hours 0.8x100 colonies/mL and 24 hours 2.2x100 colonies/mL. These results stated that the jamu beras kencur met the BPOM standard requirements Number 32 of 2019 which was AKK 103 Colonies/mL. The results of the Kruskal Wallis test obtained a sig value of 0.286, it was concluded that there was no effect of storage time for the jamu beras kencur on the growth of molds. The identification results on the jamu beras kencur obtained fungal species, namely Aspergillus flavus, Aspergillus niger, and Penicillium sp. Suggestions for further researchers can examine the effect of storage time on mold growth in other types of herbal medicine.
Roman Law as an Idea Basis for Punishing in the Conditions of the Slovak Republic
Authors: Mihálik Stanislav , Slovák Igor
Published: June 2022

In the presented paper, the author focuses on the study and description of the influence of Roman law, or its ideological bases, on the legal regulation of punishment through the Criminal Code in the conditions of the Slovak Republic. Author then pays special attention to the legacy of Roman law and its identification in the institutes which form the basis of the punishment mechanism, as well as the importance of this legal system for the individual basic principles on which punishment is subject in the conditions of the Slovak Republic. Finally, the author also deals with the method of punishing the so-called concurrence of criminal offenses (as a form of multiple crime), in comparison with the basic approaches that were created in the given sphere by the legal system of Roman law.
Patterns of Healthcare Use and Mortality After Alzheimer’s Disease or Related Dementia Diagnosis Among Alaska Native Patients: Results of a Cluster Analysis in a Tribal Healthcare Setting
Authors: Avey Jaedon P. , Schaefer Krista R. , Noonan Carolyn J. , Muller Clemma J. , Mosley Michael , Galvin James E.
Published: June 2022

Background:

Alaska Native and American Indian (AN/AI) people represent a rapidly aging population with disproportionate burdens of Alzheimer’s disease and related dementias (ADRD) risk factors.

Objective:

To characterize healthcare service use patterns and mortality in the years following ADRD diagnosis for patients in an Alaska Native Tribal health system.

Methods:

The study sample included all AN/AI patients aged 55 or older with an ADRD diagnosis who were seen between 2012–2018 ( n = 407). We used cluster analysis to identify distinct patterns of healthcare use for primary care, emergency and urgent care, inpatient hospital stays, and selected specialty care. We compared demographic and clinical factors between clusters and used regression to compare mortality.

Results:

We identified five clusters of healthcare service use patterns after ADRD diagnosis: 1) people who use a low amount of all services ( n = 107), 2) people who use a high amount of all services ( n = 60), 3) people who use a high amount of primary and specialty care ( n = 105), 4) people who use a high amount of specialty care ( n = 65), and 5) people who use a high amount of emergency and urgent care ( n = 70). The cluster with the highest use had the greatest proportion of comorbidities and had a 2.3-fold increased risk of mortality compared to the cluster with the lowest healthcare service use.

Conclusion:

Results indicate that those receiving the most services had the greatest healthcare-related needs and increased mortality. Future research could isolate factors that predict service use following ADRD diagnosis and identify other differential health risks.
Trunk muscle activation in side plank exercises with and without external-focus instruction
Authors: Murofushi Koji , Oshikawa Tomoki , Akuzawa Hiroshi , Yamaguchi Daisuke , Hirohata Kenji , Furuya Hidetaka , Mitomo Sho , Kaneoka Koji , Yagishita Kazuyoshi
Published: June 2022

BACKGROUND:

Trunk muscle activity during isometric exercise is altered by external-focus instruction.

OBJECTIVE:

To check alterations in trunk muscle activity during side plank exercise both with and without instructions to refrain from crushing an item (external-focus instruction method).

METHODS:

Twenty-one healthy men aged 20–49 participated in this study. Ten trunk muscle activities were measured using surface electromyography during side plank exercises both with and without external-focus instruction. The unpaired t-test or Mann–Whitney U test was used to compare differences between exercise tasks and between sides.

RESULTS:

Side plank exercise with external-focus instruction increased activity of the upper trapezius, lower trapezius, latissimus dorsi, medial head of the triceps, and internal oblique on the supported side when compared with that without external-focus instruction ([Formula: see text] 0.05 for all). On the unsupported side, side plank exercise with external-focus instruction significantly increased activity of the upper trapezius, lower trapezius, latissimus dorsi, medial head of the triceps, clavicular part of the pectoralis major serratus anterior, external oblique, rectus abdominis, internal oblique, and multifidus when compared with that without external-focus instruction ([Formula: see text] 0.001 for all).

CONCLUSIONS:

Adding the external-focus instruction method to the conventional side plank exercise may be effective in increasing the trunk muscles’ activity.
Effect of novel diagonal stretching combining trunk rotation and trunk flexion on contralateral knee extension
Authors: Lim Wootaek
Published: June 2022

BACKGROUND:

Most previous studies have focused on increasing hamstring flexibility when knee extension range of motion (KE ROM) is restricted. However, it was demonstrated that the tensile force generated in the upper body could be transmitted to the contralateral lower extremity.

OBJECTIVE:

This study examined the effect of novel diagonal stretching combining trunk rotation and trunk flexion on the contralateral KE ROM.

METHODS:

Two different positions (sitting with a neutral pelvis position and sitting with trunk rotation) were randomly selected and the contralateral and ipsilateral KE ROM was measured in each position. As for the stretching intervention, trunk rotation and slight trunk flexion were applied in sitting with a neutral pelvic position.

RESULTS:

On the contralateral side, KE ROM was significantly different in all pairwise comparisons ([Formula: see text] 0.001). On the ipsilateral side, a significant difference in KE ROM was only observed between measurements taken after stretching compared to measurements taken during trunk rotation ([Formula: see text] 0.005).

CONCLUSIONS:

The tensile force in the upper body significantly affects tissue extensibility in the lower extremity in the contralateral side, leading to the restriction of active maximum knee extension. Diagonal stretching techniques may successfully enhance mobility in the contralateral leg.
Association of Depressive Symptoms and Cognition in Older Adults Without Dementia Across Different Biomarker Profiles
Authors: Rubin-Norowitz Mariel , Lipton Richard B. , Petersen Kellen , Ezzati Ali ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: June 2022

Background:

Depression is a late-life risk factor for cognitive decline. Evidence suggests an association between Alzheimer’s disease (AD) associated pathologic changes and depressive symptoms.

Objective:

To investigate the influence of AT(N) biomarker profile (amyloid-β [A], p-tau [T], and neurodegeneration [N]) and gender on cross-sectional associations between subclinical depressive symptoms and cognitive function among older adults without dementia.

Methods:

Participants included 868 individuals without dementia from the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Depressive symptoms were measured using the Geriatric Depression Scale (GDS). ADNI neuropsychological composite scores assessed memory and executive function (EF). PET, cerebrospinal fluid, and MRI modalities classified the study sample into biomarker profiles: normal biomarkers (A–T–N–), AD continuum (A+T±N±), and suspect non-AD pathology (SNAP; A–T±N–or A–T–N±). Multivariate regression models were used to investigate associations between GDS and cognitive domains.

Results:

GDS was negatively associated with memory (β= –0.156, p < 0.001) and EF (β= –0.147, p < 0.001) in the whole sample. When classified by biomarker profile, GDS was negatively associated with memory and EF in AD continuum (memory: β= –0.174, p < 0.001; EF: β= –0.129 p = 0.003) and SNAP (memory: β= –0.172, p = 0.005; EF: β= –0.197, p = 0.001) subgroups. When stratified by sex, GDS was negatively associated with memory (β= –0.227, p < 0.001) and EF (β= –0.205, p < 0.001) in men only.

Conclusion:

The association between subclinical depressive symptoms and cognitive function is highly influenced by the AT(N) biomarker profile.
The Tryptophan Catabolite or Kynurenine Pathway in Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Authors: Almulla Abbas F. , Supasitthumrong Thitiporn , Amrapala Arisara , Tunvirachaisakul Chavit , Jaleel Al-Karrar Kais Abdul , Oxenkrug Gregory , Al-Hakeim Hussein K. , Maes Michael
Published: June 2022

Background:

Alzheimer’s disease (AD), which is characterized by progressive brain dysfunction and memory loss, is one of the most significant global health concerns for older adults. Neuroinflammation and increased oxidative stress contribute to the pathophysiology of AD, thereby presumably inducing tryptophan (TRP) degradation through the TRP catabolite (TRYCAT) pathway.

Objective:

To delineate the activity of the TRYCAT pathway along with levels of TRP and tryptophan catabolites (TRYCATs) in AD patients.

Methods:

We used PubMed, Google Scholar, Web of Science, and SciFinder during the month of January 2022 to gather the pertinent publications. We found 19 eligible articles which involved 738 patients and 665 healthy controls.

Results:

Our results revealed a significant difference ( p = 0.008) in the kynurenine (KYN)/TRP ratio (standardized mean difference, SMD = 0.216, 95% confidence interval, CI: 0.057; 0.376), and a significant decrease in TRP in AD patients (SMD = –0.520, 95% CI: –0.738; –0.302, p < 0.0001). Moreover, we also found a significant increase in the central nervous system (CNS), brain, and cerebrospinal fluid kynurenic acid (KA)/KYN ratio but not in peripheral blood, as well as a significant decrease in plasma KA and xanthurenic acid in the CNS and blood.

Conclusion:

AD is characterized by TRP depletion but not by an overactivity of the TRYCAT pathway. IDO-induced production of neurotoxic TRYCATs is not a key factor in the pathophysiology of AD.
RETRACTED: CVDP k-means clustering algorithm for differential privacy based on coefficient of variation
Authors: Kong Yuting , Qian Yurong , Tan Fuxiang , Bai Lu , Shao Jinxin , Ma Tinghuai , Tereshchenko Sergei Nikolayevich
Published: June 2022

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
Applicability of an electrical resistance modulator device in the rehabilitation of a person with spinal cord injury
Authors: Celetto Marco , Zullo Leonardo , Blanco Rosmary , Maieron Manuela , Dal Mas Francesca , Biancuzzi Helena , Bongiorno Giulia , Rizzardo Alessandro , Bizzarini Emiliana , Miceli Luca
Published: June 2022

INTRODUCTION:

Technology is in rapid and continuous evolution. The recovery of functions, motor, and cognitive activities benefits from it to define new outcome measures and new rehabilitation processes. This study evaluates the applicability of an electrical resistance modulator device for rehabilitation purposes for a person with spinal cord injury.

MATERIALS AND METHODS:

The study sample consisted of 10 healthy, able-bodied subjects assessed in a light wheelchair. A resistance training mode is compared using the electrical resistance modulator device and a standard strength training protocol with the aid of two weights, through an electromyographic and a kinematic evaluation with a triaxial accelerometer. The movements investigated consist of arm abduction-adduction, arm elevation-extension and elbow flexion-extension.

RESULTS AND DISCUSSION:

In the flexion-extension gesture of the arm, there is a greater symmetry of muscle activation and less activation of the muscles not directly involved in the movement during the use of the electrical resistance modulator device. In the flexion-extension of the elbow and flexion-extension of the shoulder, the muscle power expressed through the electrical device is greater, while in the abduction-adduction of the shoulder, it is more significant with weights. For the joint Range of Motion, the duration of the motion cycles and their symmetry, there are no significant differences between the two experimental conditions.

CONCLUSIONS:

The study results confirm that training for increasing muscle strength in a person with spinal cord injury can be performed using the electrical resistance modulator device. There are no contraindications to its use nor greater risks for the subject’s health. Further studies are needed to investigate the benefits of using the electrical device in the early stages of rehabilitation of a person with spinal cord injury.
The effects of cooling vests on thermoregulatory responses and exercise performance in individuals with spinal cord injury: A systematic review
Authors: Silva Samuel , Castilho Mariana , Stieler Eduardo , Lôbo Ingrid Ludimila Bastos , de Mello Marco Túlio , Silva Andressa
Published: June 2022

BACKGROUND:

Individuals with spinal cord injury (SCI) present thermoregulatory impairments that prejudice thermal compensation and heat dissipation during exercise practice. Thus, cooling vests (CV) seems to be a promising strategy to attenuate it.

OBJECTIVE:

Our aim was to evaluate the efficacy of CV in controlling the rise in body temperature and in enhancing exercise performance in individuals with SCI.

METHODS:

The searches were performed in PubMed, Web of Science, Scopus, PEDro, and SciELO databases. We selected randomized controlled trials, quasi-randomized trials, or cross-over trials that evaluated the efficacy of CV before or during exercise practice in thermoregulatory responses and exercise performance of individuals with SCI.

RESULTS:

A total of 400 reports were identified through databases searches and another article was found through citation searching. Seven cross-over trials were included in this review after the screening processes.

CONCLUSION:

CV may not be effective in attenuating the rise in core temperature in persons with SCI, but it seems to be effective in controlling skin temperature and in improving thermal comfort/sensation. It is unclear whether the CV is more effective when applied before or during exercise practice. Individuals with tetraplegia may benefit more and the CV may be more effective in strenuous exercises.
The node deployment of wireless sensor networks based on mobile edge computing
Authors: Zhou Fangrong , Yang Hemeng , Ma Yi , Chen Yanfang , Wen Gang , Cheng Yansheng
Published: June 2022

When deploying network nodes, there are many redundant nodes, low network coverage and high energy consumption of network nodes, the node deployment method of wireless sensor networks(WSN) based on mobile edge computing is studied. WSN nodes are divided into anchor nodes and unknown nodes. Taking the location information of anchor nodes as a reference, the specific location of unknown nodes is obtained by trilateral measurement. Minimizing the node distance error is taken as the objective function, and the cuckoo search algorithm is used to solve it to obtain the final location result of the node. The mobile edge computing method is used to design the node deployment method of WSN to complete the node deployment. Simulation results show that the number of redundant nodes in this method is 3, maximum network coverage is 89%, maximum energy consumption of network nodes is 34.3J.
Theoretical and methodological model of criminalistics and its new directions
Authors: Shepitko Valerii
Published: June 2022

This research paper purpose is to find out tendencies of development of criminalistics in globalized world, define its borders, forecast emergence of new directions and to characterize them.

Theoretical and methodological model of criminalistics is studied, tendencies and specifics of formation of criminalistics in modern conditions are traced.

Formation of internal structure of criminalistics (its system) is considered, connection with other sciences (natural sciences, humanities, social, formal) is determined, relationship with forensic sciences (forensicmedicine, forensic toxicology, forensic psychology, forensic chemistry, etc.) and forensic expertology is established. Attention is drawn to the orientation of the forensic vector of Ukraine to a single forensic European space. Necessity of creating a new section in the structure of criminology, namely: forensic strategy is substantiated.

Origin specifics, formation and development of new branches (directions) of criminology are considered: competitive, judicial, medical, genotypic, aerospace, computer (digital) and nuclear ones. Necessity of using forensic knowledge by different parties in criminal proceedings both in while of pretrial investigation and in legal proceedings is argued. The subjects of specific expertise application of forensic knowledge should be not only the investigator, but prosecutor, investigating judge, interrogator, detective, judge, lawyer.

Emergence of new branches of criminology is associated with scientific and technological progress, the emergence of new technologies, the need to work with specific traces and complexity of collecting and examining evidence. Special attention is paid to development and formation of medical, digital and nuclear forensics.
Ranking de las audiencias consignadas por la Subsecretaría del Medio Ambiente, entre 2015-2019
Authors: Toledo Aceituno Pablo , Gómez Fuentes Roberto , Moraga Araya Ángel
Published: June 2022

l objetivo de este artículo fue determinar cuál es el cargo público de la Subsecretaría del Medio Ambiente de Chile que más audiencias consignadas poseen entre los años 2015-2019, y la frecuencia de materias reportada. Se estableció que el cargo de ministro es la autoridad pública que más audiencias consignadas posee durante el periodo encuestado y la materia a tratar más recurrente fue el “diseño, implementación y evaluación de políticas, planes y programas efectuados por los sujetos pasivos”. Para el presente trabajo se realizó una exhaustiva recopilación de datos útiles, desde los registros públicos de la Subsecretaría del Medio Ambiente y del Consejo para la Transparencia. Antecedentes que una vez recogidos fueron ordenados y puestos a prueba bajo el método de los estudios comparativos, mediante el cual se estableció un ranking con los cargos con más audiencias consignadas entre los años llevados a escrutinios.
Body Image Dengan Perilaku Bullying Pada Remaja
Authors: Aironi Zuroida  , Starry Kireida Kusnadi
Published: June 2022

This study aims to determine the relationship between body image and bullying behavior in adolescents. The research method used is quantitative. The sample of this study was 60 adolescents taken by incidental sampling technique. The research data was obtained using the scale method, namely the scale of bullying behavior and the scale of body image. Data analysis using the SPSS (Statistiscal Package For Social Sciences) program, the Corralate Bivariaet program menu: Product Moment Analysis from Karl Pearson. The results of the analysis obtained the value of the correlation coefficient rxy = 0.369 Sig. and a p of 0.004 (p<0.01) means that there is a very significant positive correlation between body image and bullying behavior. A positive direction means that the higher the body image, the higher the level of bullying behavior, meaning that the hypothesis is accepted.
Konsep Diri Dalam Menghadapi Quarter Life Crisis
Authors: Luluk Masluchah  , Wardatul Mufidah  , Uti Lestari
Published: June 2022

This study aims to determine the influence of self-concept in facing the quarter life crisis in students. The hypothesis proposed is the influence of self-concept in the face of quarter life crisis in students. The research methodology used is quantitative research.The subjects of this study were 80 students between 19 and 29 years old in the city of Jombang using random sampling on purpose.The research instruments used in this study are the self-concept scale and the quarter life crisis scale. The data analysis used in this study was the correlation of moments produced through the SPSS (Statistical Package For The Social Sciences) program.Hypothesis Test obtained the correlation coefficient rxy = -0.416 with a significant 0.000 (p<0.01). This shows that there is a very significant negative correlation between self-concept and quarter life crisis, that is, the higher the self-concept, the individual does not experience a cquarter life crisis, so the hypothesis that is addressed .
PENGARUH PERSALINAN NORMAL TERHADAP PENURUNAN KADAR HEMOGLOBIN PADA IBU POSTPARTUM DI RUMAH SAKIT AL FATAH AMBON
Authors: Fasiha Fasiha , Wabula Widy Markosia , Nendissa Mintje Maria
Published: June 2022

Efforts to improve the health status of mothers and babies are one form of investment in the future. The success of maternal and infant health efforts can be seen from the Maternal Mortality Rate (MMR) and Infant Mortality Rate (IMR) indicators. Women die from complications during and after pregnancy and childbirth. The main complications that cause almost 75% of all maternal deaths are severe postpartum bleeding, infection, high blood pressure during pregnancy (pre-eclampsia and eclampsia), complications from childbirth, and unsafe abortion. This study provides information about changes in hemoglobin levels after childbirth in postpartum mothers. Under normal circumstances, both normal delivery and normal delivery will lose blood less than 500 cc. Where the loss of blood will have an impact on the decrease in hemoglobin levels. Research conducted by the author at Al Fatah Hospital Ambon on postpartum maternal patients in the postpartum room supported by examination of hemoglobin levels. Data analysis using Paired Sample Test. The results of this study showed that the average decrease in Hb levels in postpartum mothers was 1,2 gr%. Normal delivery is the process of expelling the products of conception (fetus and placenta) that are already months old or can live outside the womb through the birth canal or through other means, either with the help or without the help of one's own strength. In normal delivery there is no episiotomy process. Bleeding occurs only in broken blood vessels around the cervix or tears in the birth canal.
İslamiyet’te Buhur Geleneği ve İran Üretimi Seramik Buhurdan Örnekleri
Authors: YILMAZ ÇALIŞKAN Güler
Published: June 2022

Türk El Sanatları’nın önemli bir grubunu teşkil eden seramik eserler, toplumların yaşayışları, ekonomileri, kültürleri, gelenekleri ve inançları hakkında önemli bilgiler sunmaktadır. Günümüze ulaşan seramik buluntular; işlev, tür ve form bakımından çeşitlilik arz etmektedir. Buhurdanlar da bu zengin çeşitliliğin bir grubunu oluşturmaktadır. Buhurların konulduğu özel kaplara buhurdan veya tütsü kabı denilmektedir. İslamiyet öncesi dönemlerden beri kullanıldığı bilinen buhurdanlar; seramik, pirinç, bakır, bronz, gümüş ve altın gibi çeşitli malzemelerden üretilmiştir. Buhur kelimesi; Farsça “buhur”, Arapça “bahur” ve Türkçe “tütsü” gibi değişik isimlerle adlandırılmıştır. Kültürlerin ve dinlerin ortak mirası olarak kabul edilen buhur; gerek dini ritüellerde, cenaze törenlerinde ve evliliklerde gerekse de sihir, büyü ve şifa amaçlı kullanımının yanında mekâna güzel mistik koku yayması için yakılmıştır. Aynı zamanda insanlar buhuru sağlık alanında da tercih etmişlerdir. Bu çalışmada, İran menşeili 12. yüzyıla ait sırlı buhurdanlar ve İslamiyet’te buhur geleneği incelenerek, İslam sanatı içindeki yeri ve önemi vurgulanmaya çalışılmıştır. Çeşitli dinlerde ve inançlarda buhur yakma geleneği, özellikle dini, folklorik ve etnografik bakımdan ele alınarak, toplumlar arasındaki farklılıklar vurgulanmıştır. Ayrıca, buhur yakma geleneğinin sosyo-kültürel ve ekonomik açıdan taşıdığı anlamların tespiti amaçlanmıştır. Böylece çok az bilinen seramik buhurdanların İslamiyet’te kullanımına, işlevselliğine ve taşıdığı sembolik anlamlara dikkat çekilmesi ve bilim dünyasına katkı sunulması hedeflenmiştir.
Proposta de implementação de melhoria no setor de logística: estudo de caso da empresa CASPEM
Authors: Ferreira Giovana de Oliveira , Prado Ana Lídia , Sousa Luciana , Roberto José Carlos Alves , Costa Rejane Flores da
Published: June 2022

O presente artigo consiste em um estudo de caso realizado na empresa CASPEM – Centro Avançado de Segurança e Monitoramento LTDA, que está vinculada a prestação de serviço, localizada na cidade de Manaus. Diante disso, com base no levantamento do diagnóstico organizacional, verificou-se que a área mais crítica da organização foi a de logística. Posto isso, o seu desenvolvimento fundamentou-se na seguinte questão norteadora: quais estratégias operacionais podem ser implementadas na empresa CASPEM visando melhorar os processos logísticos da organização? Logo, estabeleceu-se como objetivo geral propor a implementação de melhorias direcionadas ao setor de logística a fim de melhorar o seu desempenho. Dessa forma, este estudo se baseou em uma pesquisa bibliográfica, de abordagem mista ou quali-quantitativa, realizada com fim exploratório através de um estudo de caso. Para tanto, utilizou-se a ferramenta da qualidade 5W2H na estruturação das propostas de implementação apresentadas no decorrer do estudo. Com isso, espera-se que a partir da implementação das propostas a empresa possa obter resultados efetivos no sentido de agregar valores e integrar os recursos, maximizando os resultados da organização.
МЕТОДИ РАННЬОЇ ДІАГНОСТИКИ ХВОРОБИ МАРЕКА
Authors: Лівощенко Л. П. , Лівощенко Є. М.
Published: June 2022

Хвороба Марека (ХМ) є значно поширеним лімфопроліферативним захворюванням переважно курей, але можуть вражатися і інші види птиці. Викликається клітинно-асоційованим герпесвірусом, що належить до підродини Alphaherpesvirinae родини Herpesviridae. ХМ призводить до величезних економічних втрат за рахунок вибраковки тушок, втрати продуктивності та якості продукції. Хоча розробка ефективних вакцин і ліній розведення курей, стійких до цієї хвороби, мала величезний успіх, але нові і більш вірулентні штами продовжують з’являтися до сьогодні. Інфікування птиці відбувається в молодому віці переважно до двох недільного віку. Хворі курчата виділяють віру в зовнішнє середовище уже через сім діб, тому рання діагностика ХМ і видалення ураженої птиці має велике значення для підтримки благополуччя стада. Тому метою цього дослідження було вивчення патології хвороби Марека у курей шляхом співвіднесення різних клініко-патологічних змін, таких як клінічні ознаки, макрозміни, цитологічні та патоморфологічні дослідження і визначення доступного методу діагностики для виробників. Гематологічний аналіз показав значне збільшення загальної кількісті лейкоцитів у птиці, ураженої ХМ, порівняно зі здоровою птицею. У захворілих курей виявляли пригніченісь, анорексію, параліч (кульгавість), сліпоту та вузилкові ураження шкіри. При розтині загиблої птиці виявлені множинні пухлини різного розміру від сірого до жовтого кольору - вузликові ураження вісцеральних органів, печінки, селезінки, легенів, серця, нирок, яєчників і ін. Одностороннє або двостороннє збільшення нервів, особливо сідничних і плечових нервів, з втратою перехресної частини. Цитологічними дослідженнями виявлено лімфоцити з тонким обідком цитоплазми та везикулярним ядром, що мали тонку мережу хроматину та виражений плеоморфізм із підвищеною клітинністю, що свідчить про хворобу Марека. Патоморфологічно в уражених органах спостерігалася інфільтрація плеоморфними, тобто малими, середніми та великими лімфоцитами та лімфобластами. Таким чином, клінічні ознаки поряд з макроскопічними, цитологічними та гістопатологічними дослідженнями пухлинних уражень підозрюваних випадків, можуть вважатися надійними та недорогими засобами для рутинної діагностики ХМ у курей у польових умовах, що сприятиме подальшому вдосконаленню діагностичних методик для ідентифікації і характеристики вірусу.
НАСЛІДКИ БАКТЕРИЦИДНОЇ ДІЇ ДЕЗІНФІКУЮЧОГО ЗАСОБУ «ДІОЛАЙД» НА ТЕСТ-ОБ’ЄКТИ З ІМІТАЦІЄЮ БІЛКОВОГО ЗАБРУДНЕННЯ
Authors: Чечет О. М. , Коваленко В. Л. , Горбатюк О. І. , Гайдей О. С. , Кравцова О. Л. , Андріящук В. О. , Мусієць І. В. , Ординська Д. О.
Published: June 2022

Птахівнича галузь України потребує швидкої модернізації для зменшення собівартості продукції з дотриманням високих стандартів її якості. В комплекс необхідних для цього заходів входить впровадження новітніх природоохоронних екологічно-безпечних технологій та забезпечення біологічного захисту птиці, тварин, людини і довкілля, що можна забезпечити якісною дезінфекцією із застосуванням нових ефективних, безпечних і дешевих дезінфекційних засобів. Новий дезінфектант “Діолайд” здатен забезпечити такі вимоги, про свідчать результати проведених лабораторних випробувань з визначення його оптимальних концентрацій за симуляції білкового забруднення з використанням тест-об’єктів у вигляді кахельних плиток, на які наносили добові тестові культури окремо Staphylococcus аureus АТСС 25923 і Pseudomonas aeruginosa АТСС 15442 та стерильну інактивовану сироватку крові великої рогатої худоби в якості білкового забруднювача. Дослідження робочих розчинів “Діолайд” 0,04 % (100 мг/дм3 за двоокисом хлору); 0,06 % (150 мг/дм3); 0,1 % (250 мг/дм3) і 0,16 % (400 мг/дм3) аналогічно та проводили триразово за експозицій 20, 30 і 60 хв. Після посівів та їх інкубування ефективність різних концентрацій нового дезінфектанта “Діолайд” визначали її спроможністю забезпечувати 99,99 % загибелі оброблених тестових бактерій. Одержані результати експерементів показали неефективність усіх робочих розчинів нового дезінфектанту за експозиції 20 хв, що було підтверджено ростом тестових культур у всіх посівах. Застосування експозиції у 30 хв виявилося ефективним, оскільки за дії робочих розчинів, починаючи від 0,06 % і вищих концентрацій дезінфікуючого засобу “Діолайд” спостерігалося повне знешкодження тестових бактерій, що підтверджувалося повною відсутністю їх росту на середовищах за інтенсивного росту у контролях. За аналізом проведених експериментів встановлено найбільш оптимальну концентрацію робочого розведення нового дезінфектанта “Діолайд” на рівні 0,06 % (150 мг/дм3 за двоокисом хлору), оскільки за його дії протягом 30 хв і довше в умовах імітації білкового забруднення забезпечувалося повне 100,0 % знешкодження тестових бактерій Pseudomonas aeru ginosa АТСС 15442 та Staphylococcus aureus АТСС 25923.
ВПЛИВ BACILLUS SUBTILIS НА ПОРОСЯТ НА ВІДЛУЧЕННІ
Authors: Шкромада О. І. , Фотіна Т. І. , Фотіна Г. А. , Нечипоренко О. Л. , Петров Р. В. , Фотін А. І.
Published: June 2022

Інтенсивне вирощування свиней призводить до погіршення санітарно-гігієнічних умов утримання. Крім того, виробничі стреси сприяють зниженню резистентності організму тварин. Прорив імунітету відображається на збільшенні випадків інфекційних захворювань серед молодняку. Для запобігання невиправданого використання антибіотиків та покращення імунної відповіді у поросят були проведені випробування пробіотичних штамів Bacillus subtilis у господарстві з розведення свиней «Інституту сільського господарства Північного Сходу» НААН України з жовтня по листопад місяць 2021 року. Об’єктом досліджень були поросята (до 30 діб) на дорощуванні породи Ландрас + Велика. Пробіотичні штами бактерій родів Bacillus subtilis Wogene, Bacillus subtilis Hanzhou VEGA, Bacillus subtilis Hansen та Bacillus subtilis Challenge задавали поросятам з розрахунку 0,3 кг на тонну води. Вміст бактерій роду Bacillus subtilis КУО/г: 4 - 4,5×109 КУО в 1 г. Умови утримання та відгодівлі у контрольній та досвідчених групах були однаковими. Адгезивні властивості Bacillus subtilis досліджували за методом В.І. Бриліса. Для проведення біохімічного аналізу кров отримували із яремної вени. Вміст загального білка та його фракції визначали за допомогою автоматичного біохімічного аналізатора із застосуванням відповідних діагностичних систем. Дослідженнями встановлено, що найбільший середньодобовий показник приростів спостерігали у групі поросят, де випоювали B. subtilis Chellenge. Різниця між контрольною та дослідними групами становила 2,08 %. Показники метаболізму у поросят у групі з B. subtilis Chellenge мали вищій рівень лізоциму на 14,7 %; γ-глобуліну – на 6,9 % та альбуміну – на 2,9 %, порівняно з контрольною групою тварин. Найбільш високі показники адгезії також мав штам B. subtilis Challenge ІАМ 4,86±0,24. За результатами проведених досліджень встановлений максимально ефективний штам бактерій для використання в даному свинарському господарстві Bacillus subtilis Challenge, який можна застосовувати поросятам як альтернативу антибіотикам. Також було встановлено, що використання Bacillus subtilis в раціоні дослідних тварин покращує метаболізм білка в організмі. Перспективою подальших досліджень у цьому напрямку є визначення механізму дії пробіотиків Bacillus subtilis на ізоляти патогенних мікроорганізмів та визначення лікувального ефекту на свинях.
ОГЛЯДОВА СТАТТЯ ЗАСТОСУВАННЯ БІОДОБАВОК: НУТРИЦЕВТИКІВ, ПАРАФАРМАЦЕВТИКІВ, ПРОБІОТИКІВ В РАЦІОНАХ ТВАРИН-КОМПАНЬЙОНІВ
Authors: Шульга А. Р. , Фотін О. В.
Published: June 2022

Протягом останнього десятиліття використання біодобавок у харчуванні людини стало досить популярно, на теперішній час це також відбувається і в харчуванні домашніх тварин, а саме застосування біодобавок в раціонах собак та кішок зустрічається досить часто як у всьому світі, так і в Україні. Але використання біологічних добавок в раціонах домашніх тварин має і багато суперечок, є сумніви що використання біодобавок в раціонах тварин компаньйонів має взагалі сенс, а також є результати досліджень що відображають навіть шкоду від неправильного застосування. І також ще й досі існує твердження серед власників тварин, що кішка як облігатний хижак харчується м’ясом і ніякої іншої їжі (наприклад рослинної) не потребує. Багато власників котів взагалі годують своїх улюбленців тільки м’ясом, рибою та молоком. Вже існує багато досліджень, що таке харчування не тільки не корисне, а ще й небезпечне для тварини. Будь-який хижак, і зокрема, кішка, потребує вуглеводів, вітамінів, мінеральних речовин, жирних кислот та інших компонентів рослинної їжі. Харчування кішок обов’язково повинно бути збалансованим, надходження до іх організму з їжею чотирьох особливо важливих компонентів: білків, жирів, вуглеводів, вітамінів та мікроелементів є вкрай необхідним і нестача чи надлишок будь-якого з них призводить до порушення обміну речовин і спричиняє величезну шкоду здоров’ю. Ще одним з цікавих питань є використання саме пробіотиків та пребіотиків, іх вплив на імунну систему тварин, навкруги доцільності та корисності іх застосування тваринам компаньйонам, а саме котам існує багато дискусій. Після опрацювання великої кількості досліджень, можна зазначити, що використання біодобавок для харчування тварин компаньйонів має свій важливий потенціал, але все ж таки саме ветеринарний лікар повинен вибрати оптимальну дієту із застосуванням відповідних біодобавок і для цього лікар повинен зібрати дієтологічний анамнез. Саме лікар ветеринарної медицини повинен допомогти власникові домашніх тварин зорієнтуватися на ринку біодобавок, призначених для особливих поживних цілей і вибрати найбільш оптимальні з них для своїх домашніх улюбленців.
Zengî Atabeyliği ve Kudüs Haçlı Krallığı’nın Mısır Üzerinde Hâkimiyet Mücadelesi
Authors: MOLLAİBRAHİMOĞLU Mustafa , ARSLAN İhsan
Published: June 2022

Öz: Haçlı Seferleri ilk olarak Filistin merkezli olmak üzere Doğu Akdeniz’de cereyan etmiştir. Ancak II. Haçlı Seferi’nin başarısızlığa uğraması ve Suriye ve çevresinde Zengî hâkimiyetinin güçlenmesiyle Haçlılar Mısır’a yönelmişlerdir. Filistin ve Suriye’de siyasî durumun Haçlılar aleyhine değişmesinin yanında Mısır’da hüküm süren Fâtımî Halifeliği’nin son derece karmaşık bir sürece girmesi de Kudüs Haçlı Krallığı için bölgeyi daha cazip hale getirmişti. Bunun yanında, Fâtımîlerin devrik veziri Şâver b. Mücîr’in yardım talebi sebebiyle Zengî Atabeyliği bu bölgede tasarrufta bulunma imkânı elde etmiştir.

Bu çalışmada, Fâtımî Halifeliği’nin içinde bulunduğu siyasî krizden başlayarak Haçlılar’ın Askalân’ı zaptı incelenecektir. Ayrıca Zengîler’le Kudüs Haçlı Krallığı arasında yaklaşık on yıllık bir dönemi kapsayan Mısır’da hâkimiyet kurma mücadelesi ele alınacaktır.
Relaciones y conexiones de la formación docente en tiempos de complejidad: una vía para la resignificación de la práctica pedagógica interdisciplinar
Authors: Saker García Janeth , Barrera Saker Luz Adriana
Published: June 2022

El propósito de este ensayo es presentar las relaciones que se dan en torno a la tríada conformada por las categorías de formación docente, práctica pedagógica interdisciplinar y mundo complejo, para responder a los desafíos que demanda la sociedad planetaria en el contexto emergente de la educación del siglo XXI. De esta manera, el presente ensayo aborda la formación docente como un referente estructural para el desarrollo y posicionamiento de la educación. Asimismo, considera que una práctica interdisciplinar y religante requiere una ruptura paradigmática docente, con capacidad para desaprender y emprender acciones transformadoras, mediante diálogos multi-, inter- y transdisciplinares. El documento se integra por cuatro apartados: en el primero se analizan las relaciones y conexiones desde la incertidumbre como una forma de repensar la formación docente; en la segunda parte, se transita entre la certeza y la incertidumbre en una revisión de pensadores en una vía entre paradigmas; en tercer lugar, se trabaja en la relación dialógica, epistemológica y gnoseológica de la formación docente; por último, se avanza en la comprensión de saberes emergentes en el contexto de una nueva formación docente. Se concluye en la necesidad de aprender nuevas relaciones en la reconceptualización de la formación docente-práctica.
Factor Associated With Sleep Disturbance and Its Consequence in Jet-Lagged Employee
Authors: Jang Hyeyeon , Kim Seog Ju
Published: June 2022

Objective: The current study aims to explore the determinants of sleep disturbance (insomnia and daytime sleepiness) and its potential consequence (depression, somatization, fatigue, and cognitive failure) on jet-lagged employee.Methods: One-hundred twenty JLEs (49 males and 71 females) completed an online survey. The survey asked for information regarding jet lag and administered eight self-report questionnaires: Ford Insomnia Response to Stress Test for sleep reactivity, Glasgow Sleep Effort Scale for dysfunctional sleep efforts, Insomnia Severity Index for insomnia, Epworth Sleepiness Scale for daytime sleepiness, Center for Epidemiologic Studies-Depression scale for depression, Somatization Subscale of the Symptom Checklist 90-item for somatic symptoms, Fatigue Severity Scale for fatigue, and Cognitive Failure Questionnaire for cognitive impairments.Results: Higher sleep reactivity (β=0.45, p<0.001) and sleep effort (β=0.40, p<0.001) significantly predicted insomnia. Higher sleep reactivity (β=0.40, p<0.01) significantly predicted sleepiness. Higher insomnia and sleepiness significantly predicted depression (β=0.50, p<0.001, β=0.22, p<0.01, respectively) and somatic symptoms (β=0.46, p<0.001, β=0.22, p<0.01, respectively). Flight time per flight (β=0.22, p<0.01), higher sleep reactivity (β=0.20, p<0.05), and higher insomnia severity (β=0.43, p<0.001) significantly predicted fatigue. Higher sleep reactivity significantly predicted cognitive failure (β=0.35, p<0.001).Conclusion: This current study reports that sleep reactivity and sleep efforts of JLEs are associated with their sleep disturbances more than other flight-related factors. Sleep disturbances of JLEs are associated with increase depression, somatization, and fatigue. Sleep reactivity caused by stressful situation are associated with fatigue and cognitive impairments of JLE. The current study suggests that management of sleep and stress may be helpful for the mental and physical well-being of JLE.
Eveningness and Impulsivity in Euthymic Mood States Adversely Affect the Quality of Life of Major Depression and Bipolar Disorder Patients
Authors: Kim Sojeong , Yoon Yeaseul , Lee Heon-Jeong
Published: June 2022

Objective: Chronotype and impulsivity are important features to be examined in mood disorder patients; these characteristics precede mood disorder onset and persist between mood episodes. Moreover, quality of life is an important outcome in psychiatric patients. This study investigated the interaction between these features and its effect on mood disorder patient’s quality of life.Methods: Early-onset major depressive disorder (MDD), bipolar disorder I (BD I), and bipolar disorder II (BD II) patients were recruited. Excluding 18 patients who were missing data on main variables and 5 patients who were classified as severely ill, a total of 472 euthymic patients (MDD=167, BD I=133, BD II= 172) were assessed on their chronotype, trait impulsivity, and quality of life using self-reports.Results: Both impulsivity and eveningness were negatively associated with quality of life. Regression results showed that there was a significant interaction effect between eveningness and impulsivity on quality of life. This indicates that the higher the level of impulsivity in mood disorder patients, the negative effect of eveningness on quality of life increased.Conclusion: The current study suggests that examination of impulsive personality in relation to chronotype may be important in further understanding the effects of these features on mood disorder patients’ lives.
Circadian Timing of the Female Reproductive System
Authors: Lee Yujin
Published: June 2022

Precise chronological transition is critical for a normal female reproductive system. Many epidemiologic studies have demonstrated rhythmicity in parturition during the resting phase, and even seasonal breeding. Circadian rhythms are controlled by a multi-oscillatory circadian system. These rhythms are determined by both genetic and environmental factors. The female reproductive axis is also highly rhythmic, and the hypothalamic-pituitary-gonadal axis and the hypothalamic-pituitary-adrenal axis are also functional multi-oscillatory circadian systems. Bidirectional communication between the central and peripheral tissue clocks is essential for maintaining the rhythm from ovulation to parturition. This review discusses the circadian timing of the female reproductive system, specifically its underlying metabolic and molecular clock functions. This review particularly focused on the following areas: multi-oscillatory system in the female reproductive system; the ovarian cycle and the timing of ovulation; timing of mating and seasonal reproduction; circadian rhythms in pregnancy; circadian timing of labor onset and parturition.
THE EFFECTS OF MODIFIED KNOW-WANT-LEARN STRATEGY IN MIXED-GENDER LOWER SECONDARY PHYSICS EDUCATION
Authors: Bogdanović Ivana Z. , Rodić Dušica D. , Rončević Tamara N. , Stanisavljević Jelena D. , Zouhor Zekri A. M.
Published: June 2022

The differences related to gender are evident in physics education from the early age of the students. Thus, it is important that the teaching strategies that are implemented in mixed-gender physics classrooms are appropriate for both boys and girls. This research examined physics achievement and metacognitive awareness of students in lower secondary education in relation to gender when the modified Know-Want-Learn (mKWL) strategy is implemented. During the study, the students were divided into the control group (where direct teaching was implemented) and the experimental group (where the mKWL strategy was implemented in physics teaching). Students’ physics achievement (estimated with knowledge tests) and metacognitive awareness (estimated with a questionnaire) before and after the pedagogical experiment, and also the students’ comments on the mKWL strategy (provided through an informal conversation) were analyzed. It was shown that the students’ achievement did not differ in relation to gender while girls showed higher metacognitive awareness in comparison with boys, and the mKWL strategy increased physics achievement and metacognitive awareness of both boys and girls. Furthermore, the students’ comments on the strategy were discussed. The proposed strategy is shown to be appropriate for both genders, and its implementation in physics classrooms can be recommended.
Keywords: metacognitive awareness, physics education, quasi-experimental research, students’ achievement, students’ comments
LEVEL OF ACCEPTANCE OF EPISTEMICALLY UNWARRANTED BELIEFS IN PRE-SERVICE PRIMARY SCHOOL TEACHERS: INFLUENCE OF COGNITIVE STYLE, ACADEMIC LEVEL AND GENDER
Authors: Cadena-Nogales Pedro D. , Solaz-Portolés Joan J. , Echegoyen-Sanz Yolanda , Sanjosé-López Vicente
Published: June 2022

One of the main objectives of scientific literacy is the development of rational skills and critical thinking in citizens. This is a central goal for teachers. However, beliefs that lack rational foundation and supporting evidence, named “epistemically unwarranted beliefs” (EUB), spread rapidly among the population. If teachers had some of these EUB, their work could be compromised. The aim of this research was to determine the level of acceptance of different EUB in Spanish pre-service primary school teachers and to analyze the influence of their cognitive style, gender, and academic level. Two hundred and fifty undergraduate students of Bachelor’s Degree in Primary Education participated in this study. Two questionnaires were used to collect data. ANOVA, ANCOVA, correlations, and linear regression analysis were used to quantify that influence. Results showed high levels of acceptance of some EUB in future teachers, with significant influences of gender and academic level, and a mediating role of cognitive styles. Experiential and rational cognitive styles, and academic level were significant predictors of EUB, being experiential thinking the most powerful one. Thus, pre-service teacher education should have an epistemological vigilance on future teachers’ scientific literacy and increase the presence of rational style among teachers. Keywords: cognitive style, epistemically unwarranted beliefs, gender influence, knowledge level, pre-service teachers, primary education