bluuebunny/crossref_metadata_2025 huggingface dataset:
Egy újonnan szintetizált adenozin analóg, a hipoxantin-triciklánó hatása izolált patkány bal és jobb pitvaron
Authors: Óvári Ignác , Szilágyi Viktória , Viczján Gábor , Lampé Nóra , Bege Miklós , Borbás Anikó , Herczeg Pál , Juhász Béla , Gesztelyi Rudolf , Erdei Tamás
Published: September 2022

A hipoxantin-triciklánó egy a DE GYTK Gyógyszerészi Kémia Tanszéken szintetizált adenozin analóg, melyben az adenint hipoxantin, a ribózt pedig egy kondenzált triciklikus molekularész helyettesíti. Munkánk során a hipoxantin-triciklánó hatását vizsgáltuk a pitvari myocardium A1 adenozinerg rendszerére, melynek (pozitív agonista általi) aktivációja számos protektív folyamatért, köztük negatív trop hatásokért felelős.

A vizsgálatokat hím Wistar patkányokból izolált bal pitvari fülcsén és teljes jobb pitvaron végeztük. A preparátumokat 95% O2 és 5% CO2 gázeleggyel szellőztetett, 36°C-os Krebs oldatot tartalmazó szervkádakban függesztettük fel 10 mN alapfeszülés mellett. A bal pitvarokat állandó frekvencián ingereltük (3 Hz; 1 ms; 1-1,5 V), míg a jobb pitvarok spontán húzódtak össze. A preparátumokon az adenozin és a hipoxantin-triciklánó inotrop és chronotrop hatását vizsgáltuk külön-külön és együtt, továbbá CPX (8-cyclopentyl-1,3-dipropylxanthine; reverzibilis A1 adenozin receptor antagonista) hiányában és jelenlétében.

Eredményeink alapján az adenozin mind a bal, mind a jobb pitvarokon hasonló mértékű, erőteljes negatív inotrop hatást fejtett ki. A hipoxantin-triciklánó ezzel szemben mérsékelt pozitív inotrop hatást váltott ki, ami hasonló mértékű volt a jobb és a bal pitvarokon. Az inotropia alakulásával összhangban, az adenozin markánsan negatív, míg a hipoxantin-triciklánó kismértékben pozitív chronotrop hatásúnak bizonyult a jobb pitvarokon. A CPX erősen (és szignifikánsan) gátolta az adenozin hatásait, de csak kisebb mértékű (és nem szignifikáns) gátlást hozott létre a hipoxantin-triciklánó hatásaival szemben. A hipoxantin-triciklánó hatásai teljes mértékben áttörhetőek voltak adenozinnal. Mindezek hátterében felvethető, hogy az adenozin könnyen le tudja szorítani a hipoxantin-triciklánót az A1 adenozin receptorról, de (ehelyett vagy emellett) elképzelhető, hogy a hipoxantin-triciklánó az A1 adenozin receptortól független útvonalon is hat. A hipoxantin-triciklánó tehát feltehetően a myocardialis A1 adenozin receptor reverzibilis, ortosztérikus, inverz agonistája, melynek ugyanakkor más támadáspontja is lehet a myocardiumban.
A SKILL RELATED FITNESS TEST FOR RACKET SPORTS -AN OVERVIEW
Authors: Yadav Rahul
Published: September 2022

ABSTRACT In this study, the objective is to provide knowledge regarding skill-related fitness tests of racket sports for players to identify their fitness ability, which will help them improve their performance. Racket sports is considered to be a powerful and aggressive sport, so the players require adequate physical fitness to succeed. The literature shows that there has never been a fitness test made for racket sports players, but skill-related fitness tests have been made before, so the researcher wants to motivate these researchers to construct a fitness test for racket sports to help coaches, physical educators, and players to evaluate their fitness capacity and develop training programs. Keywords:- Skill , Racket Sports, Physical Fitness ,Correlation And Evaluation
A Survey Study To Analyze Physical Literacy In Physical Educators
Authors: Choudhary Prashant Kumar
Published: September 2022

ABSTRACT The purpose of the study was toanalyze physical literacy among physical educators. For the purposes of research N =117, physical education teachers were selected by snowball sampling technique. The age of the subject was (23-45± 2.09). For the collection of data Perceived, Physical Literacy Instrument (PPLI) questionnaire by Waisum (et al., 2016) was used to investigate physical educators' perception of physical literacy. The questionnaire consists of 9 items with 3 factors measuring 1) motivation, 2) confidence, and physical competence and 3) engagement with the environment. The reliability of this questionnaire range from 0.73 to 0.76. Questionnaires were sent through google forms and were also circulated physically.To know the nature of data and for testing the assumption of normality, descriptive statistics (mean, standard deviation, skewness, kurtosis, etc.) and Shapiro– Wilk’s test was used. All data are presented as mean with standard deviations.for further analysis chi-square, Non-parametric statistics was used to analyze the data. The result was shown after analyzing the (PPLI) tool on physical educators’ perception of their physical literacy in regard tothe sense of self and self-confidence, self-expression and communication with others, knowledge and understanding.As the analysis of the result carried out on the chi-square test was found to be significant at a 0.05 level for all three factors in the questionnaire. Keywords – PPLI Questionnaire, Physical Education, Physical Literacy,snowball sampling, Three-Factor
IMPLEMENTASI PROGRAM PENGHIJAUAN DI PT SEMEN BATURAJA (PERSERO) Tbk.
Authors: Hapsari Rindy Putri
Published: September 2022

Reforestation is an effective and efficient activity to reduce global warming and reduce carbon emissions. Reforestation efforts are often carried out by several agencies, including the Government, State-Owned Enterprises (BUMN), the private sector, and other institutions. This study aims to investigate the successful implementation of the reforestation program at PT Semen Baturaja (Persero) Tbk. The method used in this research is descriptive qualitative, using the implementation model proposed by Ripley and Franklin. Findings in the field indicate that the implementation of the reforestation program at PT Semen Baturaja (Persero) Tbk has been successful and shows optimal results. This success is tested through a study of three dimensions of successful implementation, namely the level of compliance, smooth functioning, performance, and impact of the reforestation program. The success of the implementation can also be seen from the level of employee compliance with the greening SOPs applied, the implementation of silviculture-based reforestation routines, and the achievement of targets and standards for the number of seeds planted. In addition, Semen Baturaja has also succeeded in distributing seeds to communities around the company such as Non-Governmental Organizations (NGOs), educational institutions, and environmentalists or nature lovers.
Invasiveness Risk Assessment of Non-native Freshwater Fish Species (Order: Siluriformes)for Lake Taal, Philippines
Authors: To Dale Anthony , Gomez Geoffrey Miguel , Ramos Diego Rafael , Palillo Charles David , Go Neil Kendrick , Gilles Allan , Briones Jonathan Carlo , Pavia Richard Thomas
Published: September 2022

Biological invasions caused by the introductions of non-native species (NNS) into their non- native ecosystems have long been a global environmental concern. In the Philippines large-scale importation of non-native freshwater fish species for the aquarium and aquaculture industry have been documented as early as 1940s. However, little invasiveness assessment has been done in the past, which resulted to the invasion of some of these exotic species. Thus, in this paper, 25 NNS (Order: Siluriformes) were assessed using the Aquatic Species Invasiveness Screening Kit (AS-ISK) to determine their potential for becoming invasive in the chosen risk assessment (RA) area, as well as their ecological and socioeconomic potential impacts on the Philippines. Based on the comprehensive ROC Curve, with the use of the Youden-J index, overall threshold values of ≥ 35 for basic risk assessment (BRA) and ≥ 47 for BRA + climate change assessment (CCA) were established to categorize the potential invasiveness of each species as low-, medium-, or high-risk. According to BRA, 10 (40%) NNS were screened as highly invasive, 14 (56%) with medium risk, and one (4%) with low risk. For BRA + CCA, 10 (40%) NNS were categorized as highly invasive, 12 (48%) with medium risk, and three (12%) with low risk. These findings highlight the need for more RAs of the non-native fish species that enter the country through the ornamental industry, as well as improved public educational campaigns and comprehensive regulatory and management policies to prevent their future invasion.
Growth of Harmful Dinoflagellate Margalefidinium polykrikoides in Different Nutrient Concentrations
Authors: Al-Has Asilah , Mohammad-Noor Normawaty , Shaleh Sitti Raehanah Muhamad , Adam Aimimuliani , Azrinor Wan Arina , Weliyadi Encik
Published: September 2022

Margalefidinium polykrikoides blooms resulted in massive fish mortality in many countries around the world. The prevalence of booms is believed to be associated with the eutrophication of the coastal area. Therefore, this study aims to determine the effects of different nitrogen (N) and phosphorus (P) concentrations on the growth of M. polykrikoides. Experiments were conducted on M. polykrikoides isolated from the affected area by exposing the cell to various N and P ratio: seawater without the addition of N and P (SW), equal N:P ratio (NP), trial ratio of N and P (TR), F/2 medium (+NP), deficient N (–N), and deficient P (–P). The experiments were carried out in triplicates for 20 d in similar environmental conditions with the determination of density, specific growth rate, and cell size during the study period. Furthermore, nutrient concentrations nitrite+nitrate (NO2 –+NO3 –), phosphate (PO4 3–), and ammonia (NH4 +) were measured initially in the medium and both nutrients and chlorophyll were determined at the end of the experiment. The results revealed that M. polykrikoides grew in all the experiments, but the growth patterns differed between the treatments. The highest specific growth rate (0.1901 ± 0.017 d–1) with the highest cell density (1709 ± 68.21 cells mL–1) with a long chain of cells was observed in TR during the exponential phase. However, cell size was significantly smaller in SW compared to other nutrient conditions during the exponential phase. This study shows that M. polykrikoides a flexible species in nutrient uptake, thus allowing the species to survive in different nutrient conditions. The understanding of this bloom mechanism is important in monitoring and management of this harmful species, particularly in Sabah coastal waters.
Macroplastic Transport and Deposition in the Environs of Pulauan River, Dapitan City, Philippines
Authors: Requiron Judea Christine , Bacosa Hernando
Published: September 2022

Plastic pollution is an emerging threat in the riverine ecosystem that affects the marine ecosystem. The Philippines, being an archipelago, is heavily dependent on its marine ecosystem. It is also considered the largest emitter of plastic via rivers. Despite this, limited field studies have been conducted to validate this finding, which is mainly based on numerical models. In this study, we determined the prevalence of macroplastics in Pulauan River, Dapitan City by observing the plastic flux and further comparing the morning and afternoon flux. Macroplastic collection was also performed to compare the plastic densities of three stream areas: upstream, midstream, and downstream. Results show that macroplastic flux in the morning (304 items/h) was significantly higher than in the afternoon (91 items/h). The correlation of macroplastic flux and flow velocity was determined to be positive – suggesting that as macroplastic flow velocity increases, plastic flux tends to increase. Macroplastic collection results showed that upstream density (0.074 items/m2) is significantly lower than midstream (0.559 items/m2) and downstream (0.473 items/m2) densities. This shows that the nearer the area is to the river mouth, the more susceptible it is to plastic litter deposition. The composition of the macroplastic litters observed and collected was attributed to the influences of human activities (aquaculture, fishing, and residential) – where food packaging, plastic bags, and plastic fragments are the top three most abundant. Due to the limitations of this study, there is a need to investigate further the different factors on the transportation and deposition of macroplastic litters in Pulauan River that can help to avoid threats in the aquaculture sector, for which the river is known.
Phylogenetic Analysis of Philippine Native Pigs (Sus scrofa L.) from Batanes, Quezon, and Marinduque Based on Mitochondrial DNA D-loop Markers
Authors: Manuel Ma. Carmina , Li Kuan-Yi , Ju Yu-Ten , Laude Rita
Published: September 2022

By analyzing the mitochondrial DNA (mtDNA) displacement loop (D-loop) region, we aimed to assess the genetic diversity of Philippine native pigs from Batanes, Quezon, and Marinduque and to determine the phylogenetic relationship between these subpopulations and other Asian and European pig breeds. Ear tissue samples were collected from the native pigs in Batanes (n = 17), Quezon (n = 37), and Marinduque (n = 40). Genomic DNA was extracted, and the D-loop sequences were amplified by PCR. The D-loop sequences of 94 Philippine samples were initially analyzed using the Kimura 2-parameter model and neighbor-joining method in MEGA7, identifying a total of 17 haplotypes designated as H1–H17. Notably, only eight haplotypes were specific to individuals coming from a particular province, whereas the remaining haplotypes were detected in samples from different provinces. Additional qualitative trait analysis that the majority of Philippine native pigs had black coat color, a plain coat pattern, short cylindrical snouts, straight head profiles, erect and forward-oriented ears, curly tails, and straight backlines. Phylogenetic analysis of the Philippine samples and 16 exotic pig breeds revealed that Philippine native pigs with H1 and H2 haplotypes formed a distinct clade with Taiwanese Type I Lanyu pig, whereas those with H3–H17 haplotypes clustered with other Asian and European pigs. Therefore, our findings suggest a close and unique relationship between Taiwanese Type I Lanyu and Philippine native pigs. The presence of several haplotypes also implies high genetic variation among Philippine native pigs. Specifically, the native pigs from Quezon and Marinduque are the most closely related, whereas those from Quezon and Batanes are the least closely related.
Stabilization of Acidified Whey Drink Made from Buffalo (Bubalus bubalis) Milk with the Addition of Pectin from Mango (Mangifera indica) Peels
Authors: Abella Mina , Gragasin Ma. Cristina , Saturno Patrizia Camille , Baltazar Teresita , Villota Sheryll May
Published: September 2022

Different levels (0.15, 0.20, and 0.25%) of commercial pectin (CP) and mango peel pectin (MPP) were used in the quality improvement of acidified whey drink (AWD) made from buffalo milk. Samples were evaluated for physico-chemical properties, microbiological qualities, sedimentation stability, and sensory characteristics. The treatment found to be the most acceptable and with the least percentage of sedimentation was subjected to product stability evaluation during storage for 27 d. No significant differences were observed among the treatments in terms of pH and total soluble solids (TSS), whereas viscosity increased as the level of pectin was increased. All the treatments for both CP and MPP had an aerobic plate count (APC) of < 10 cfu/mL, yeast and molds count of < 1cfu/mL, coliform count of < 1cfu/mL, and negative in E. coli. Moreover, both CP and MPP at the 0.25% level showed the lowest sedimentation with 0.76%. Results showed that AWD with 0.25% MPP can be stored for about 20 d at ambient temperature.
Relaciones laborales 4.0: Las criptomonedas como medio de pago
Authors: Puntriano Rosas César
Published: September 2022

Las Tecnologías de la Información y la Comunicación han venido a trastocar nuestra vida cotidiana y, qué duda cabe, a las relaciones laborales. Pero esto último no solo desde una facilitación del ejercicio de la actividad laboral a través de nuevas formas de trabajo como el teletrabajo, o del fortalecimiento del poder de dirección empresarial a través del uso de la videovigilancia, sino también mediante el divorcio de los esquemas tradicionales de pago de la remuneración y de su migración hacia métodos más sofisticados como el pago con criptomonedas. En este artículo reflexionaremos sobre su viabilidad en el Perú a la luz de la legislación laboral vigente.
Apuntes sobre el impacto de la tecnología en la seguridad y salud en el trabajo en minería
Authors: Peyrone Villacorta Fiorella Pía
Published: September 2022

Se presenta un trabajo analítico sobre el impacto de la tecnología en la seguridad y salud en el trabajo minero, centrándose específicamente en la gran y mediana minería, a efectos de identificar la intervención de esta herramienta en torno a dicha materia, partiendo en que el trabajo minero uno de los principales cimientos de la economía nacional y, además es considerado como una actividad de alto riesgo de acuerdo a la legislación. Advirtiéndose, la necesidad de aplicar los criterios establecidos por la Organización Internacional en el Trabajo sobre la seguridad y salud en el trabajo, así como la importancia de que se promueva la creación de tecnologías que tengan como objetivo la prevención de riesgos en el trabajo; lo cual permite que se erijan propuestasen vías de promover una cultura de prevención.
Perceptions Reasons and Barriers in Observing Purdah (Hijab) among Female Undergraduate Medical Students
Authors: Haroon Jawaria , Hussain Abrar , Malik Farhat R , Hanif Shams ul Haq , Iqbal Maleeha , Fatima Ishrat , Ullah Irfan
Published: September 2022

Hijab is practiced by global Muslim women as an obligation of their religion and protection.The objective of this study was to determine the frequency of Hijab with comparison of the awareness, perceptions, practices and identify barriers to hijab wearing among female medical undergraduate students. A descriptive study in four randomly selected Medical Colleges of Peshawar, Pakistan was conducted among 370 female undergraduates with 95% confidence interval and 5% margin of error. All female students were included in the study with consent however sick, absent with no consent were excluded. The validated questionnaire had 18 questions of knowledge, attitude, practices and barriers. The collected data was analyzed through SPSS Version- 21 with descriptive statistics for categorical variables through frequency and percentages. A total of 327 females with response rate of 88.37% completed the questionnaires. The mean age was 20.81 + 2.48 years. Hijab wearing females were 58.8%, 16.5% were without Hijab however 83.5% females were unaware of Hijab timing. The 76.1% females had no problems in observing hijab. The 68.8% hijab wearing females were satisfied, 1.5% felt safe and 3.4% were comfortable with it. Reasons for observing purdah were 63% religious, 23.2% for protection, 2.8% as a part of uniform and 7.6% due to family pressures. Perceptions of hijab were 90.5% religious, 73.7% to society pressure, 5.8% as a part of the dress code and 3.7% as a piece of cloth only. Hijab awareness was 95.1%.This study concluded that hijab is considered a religious duty and obligation with comfort and protection among the female undergraduate students of Peshawar, Pakistan.
Analysis Study of Routing Protocols in MANET for Disaster Management
Authors: Abdul Majid  , Muhammad Saim  , Awad bin Naeem  , Muhammad Asad Soomro  , Imran Khurshid  , Muhammad Ashad Baloch
Published: September 2022

A unique instance of a wireless ad hoc network that is non-centralized, self-organized, and self-managed is known as a mobile ad hoc network(MANET). MANET used in different areas of life like a rescue operation, real-time information, interpersonal communication, information sharing and network portioning. MANET has dynamic change in nature of both its topology and nodes in order to deliver data quickly. Due to Mobility nature in nodes, there is a lot of chances of routing design issues between the nodes. There is a list of routing protocol each one has its special characteristic in Specific areas have been designed and compared their attributes on different parameters. This report gives a clear picture and a comparison of various MANET routing techniques with their limitation in ad-hoc routing network.
THE USE OF VISUAL ART TO FACILITATE STUDENTS IN LEARNING ENGLISH SPEAKING AT SMK NEGERI 2 MAKASSAR
Authors: Amirullah St. Rahma Wahyuni , Bte Abdul Nurdevi , Hafid Hilda
Published: September 2022

This thesis aimed to find out does the use of Visual Art media improve the students to speaking accuracy and make the students in easier at in speaking fluency at SMK Negeri 2 Makassar. The researcher applied pre-experimental method with one gruoup pre-test and post-test design. To collect the data, the researcher used pre-test, treatment and post-test. The result of this research showed that the result of t-test value of level significant (p) = 0.05 with degree of freedom in accuracy (pronunciation) (df) + 29. In fluency (smoothness) (df) + 29. Indicated t-table value is 1.6991 and t-table accuracu (pronunciation) is 16.784, in fluency (smoothness) 14.262. Based on the result data analysis, it is concluded that there is difference significant mean score of the test that have given by researcher using Visual Art media in teaching speaking.
TEKNIK KOMUNIKASI PERSUASIF PENGURUS PANTI ASUHAN AL AKBAR PEKANBARU
Authors: Ermairel Salim
Published: September 2022

The purpose of this study was to determine persuasive communication techniques for the administrators of the Pekanbaru Al Akbar Orphanage. Researchers used persuasive communication theory. This research method is descriptive with a qualitative approach. This research is a persuasive communication technique that needs to be applied to influence in a better direction. With persuasive communication techniques communicators can increase knowledge and change a person's attitude. Persuasive communication techniques are indispensable in conveying messages to children and adolescents. With persuasive communication techniques, communication becomes familiar, friendly, fun. Good persuasive communication techniques for children and adolescents are easy to digest the message content desired by communicators and motivate them at Al Akbar Orphanage Pekanbaru. The persuasive technique used is the management of the Al Akbar Orphanage using persuasive techniques, namely association techniques, integration techniques, reward techniques, ordering techniques so that the message conveyed by the Al Akbar Orphanage can be conveyed to foster children and can be digested properly so that they can be understood. guide and motivate foster children towards a better direction.
Peran Perempuan dalam Ekonomi Ketapang
Authors: Budiantoro Fajar
Published: September 2022

Terjadi banyak perubahan di zaman modern sekarang ini, di antaranya yaitu perubahan pekerjaan yang jumlahnya semakin banyak dan beragam. Kondisi ini dapat memengaruhi partisipasi perempuan apakah memutuskan untuk bekerja atau tidak. Penelitian ini bertujuan menganalisis permasalahan tersebut dengan model regresi logistik biner. Data berasal dari salah satu survei di BPS, yaitu Survei Sosial Ekonomi Nasional (SUSENAS) Maret 2020 Ketapang. Berdasarkan hasil analisis dengan taraf signifikansi 0,05, diperoleh estimasi parameter model dengan koefisien deteminasi regresi logistik sebesar 68,7 persen, ketepatan prediksi data sebesar 87,2 persen. Selanjutnya berdasarkan uji kecocokan model Hosmer dan Lemeshow, diperoleh data prediksi model dan data hasil observasi yang tidak berbeda secara signifikan. Variabel umur, status dalam rumah tangga, jumlah Anggota Rumah Tangga (ART), dan ijazah terakhir perempuan masing – masing secara parsial berpengaruh signifikan, yaitu secara signifikan menentukan apakah bekerja ataukah tidak bekerja.
Moderasi Islam Dan Aliran Pemikiran Pluralisme Agama
Authors: Toha Muchammad , Muna Faizul
Published: September 2022

This study examines the Islamic moderation and the religious sects of pluralism. Considering Islam is a religion that is rahmatan lil Alamin. Then, so far Islam is a peace solution to the problem of intolerance. The theory used in this research analysis uses the thoughts of several experts including Quraish Shihab, Yusuf Al-Qardhawi, Abdurrahman Wahid (Gus Dur) and Nucholis Majid. This research is a qualitative research study of literature with an interpretive philosophical approach. In obtaining valid data and supporting this research, the author uses the documentation method to collect data. Then the data analysis technique used is deductive analysis, namely drawing conclusions based on general conditions, or there are special findings from general ones. The results of this study illustrate that Islam does not consider all religions to be the same, but Islam treats all religions equally by prioritizing tasamuh (tolerance), deliberation between religious believers, and having a musawa (non-discriminatory) attitude.
Alcançando o lazer na entrevista médica
Authors: Souza Ricardo Alexandre de
Published: September 2022

A entrevista médica resume-se a organizar as informações do paciente em algoritmo médico para possibilitar as decisões e organizar o registro. O lazer é informação fundamental para compreender o contexto do sujeito. A relação da cultura com o lazer cria a necessidade de percebermos que, dependendo do lugar e do tempo, haverá algumas atividades prescritas e proscritas de lazer. Para manter uma vida ativa e de qualidade, faz-se necessário que o paciente precise, algumas vezes, da prescrição ou proscrição do lazer, que é muito mais amplo do que atividades físicas. Como possibilitar que isso ocorra e o que deve ser procurado para melhor compreender isso? O que é lazer e quais as suas formas de prescrição?
Um Sistema Inteligente para Detecção de DDoS em Ambientes Inteligentes baseado em Fog and Cloud Computing
Authors: Costa Wanderson L. , Gomes Rafael L.
Published: September 2022

Atualmente, os espaços urbanos estão implantando Ambientes Inteligentes (SE) para desenvolver infraestruturas, recursos e serviços. Os SEs são compostos por uma grande quantidade de dispositivos heterogêneos (dispositivos pessoais e IoT). Um dos problemas existentes dos SEs é a detecção de ataques de negação de serviço distribuída (DDoS), devido às vulnerabilidades dos dispositivos IoT. Dessa forma, é necessário implantar soluções que possam detectar DDoS em SEs, lidando com questões como escalabilidade, adaptabilidade e heterogeneidade. Nesse contexto, este artigo apresenta um Sistema Inteligente para detecção de DDoS em SEs, aplicando abordagem de aprendizado de máquina, computação em névoa e computação em nuvem. Além disso, a pesquisa apresenta um estudo sobre as características de tráfego mais importantes para a detecção de DDoS em SEs, bem como uma abordagem de segmentação de tráfego para melhorar a acurácia do sistema. Os experimentos realizados, usando tráfego de rede real, sugerem que o sistema proposto atinge 99% de acurácia, enquanto reduz o volume de dados trocados e o tempo de detecção.
GrADyS-SIM - A OMNET++/INET simulation framework for Internet of Flying things
Authors: Lamenza Thiago , Paulon Marcelo , Perricone Breno , Olivieri Bruno , Endler Markus
Published: September 2022

This paper describes GrADyS-SIM, a framework for simulating cooperating swarms of UAVs in a joint mission in a hypothetical landscape and communicating through RF radios. The framework was created to aid and verify the communication, coordination, and context-awareness protocols being developed in the GrADyS project. GrADyS-SIM uses the OMNeT++ simulation library and its INET model suite and allows for the addition of modified/customized versions of some simulated components, network configurations, and vehicle coordination to develop new coordination protocols and tested through the framework. The framework simulates UAV movement dictated by a file containing some MAVLink instructions and affected on the fly by different network situations. The UAV swarm’s coordination protocol emerges from individual interactions between UAVs and aims to optimize the collection of sensor data over an area. It also allows simulation of some types of failures to test the protocol’s adaptability. Every node in the simulation is highly configurable, making testing different network topographies, coordination protocols, node hardware configurations, and more a quick task.
Análise de Performance dos Modelos Gerais de Aprendizado de Máquina Pré-Treinados: BERT vs DistilBERT
Authors: Barbon Rafael Silva , Akabane Ademar Takeo
Published: September 2022

Modelos de aprendizado de máquina (AM) vêm sendo amplamente utilizados devido à elevada quantidade de dados produzidos diariamente. Dentre eles, destaca-se os modelos pré-treinados devido a sua eficácia, porém estes normalmente demandam um elevado custo computacional na execução de sua tarefa. A fim de contornar esse problema, técnicas de compressão de redes neurais vem sendo aplicadas para produzir modelos pré-treinados menores sem comprometer a acurácia. Com isso, neste trabalho foram utilizados dois diferentes modelos pré-treinados de AM: BERT e DistilBERT na classificação de texto. Os resultados apontam que modelos menores apresentam bons resultados quando comparados com seus equivalentes maiores.
OTALab: um ambiente de experimentação remota de protocolos e aplicações em Internet das Coisas
Authors: Cussuol Enzo B. , Sachetti Lucas L. S. , Santos Bruno P. , Mota Vinicius F. S.
Published: September 2022

Este artigo apresenta o OTALab, uma ferramenta para criação e implantação de ambientes de experimentação de aplicações de Internet of Things (IoT) em microcontroladores de baixo custo. O OTALab visa a rápida implantação e configuração de um testbed de ambiente de experimentação. O OTALab possui dois perfis de usuários: administradores e experimentadores. Para os primeiros, o OTALab expõe uma interface de administração capaz de adicionar/remover dispositivos IoT, serviços e funcionalidades ao sistema. Já os experimentadores podem visualizar os serviços disponíveis em cada dispositivo e enviar seu próprio código aos dispositivos via linha de comando ou interface Web. O OTALab recebe o código-fonte, compila-o para o microcontrolador específico e atualiza o firmware do dispositivo através do paradigma Over the Air (OTA). O OTALab é composto por uma biblioteca de microcontroladores, um servidor de gerenciamento de dispositivos e uma aplicação Web. A ferramenta pode ser instanciada localmente ou de forma distribuída, melhorando sua flexibilidade.
Port do Sistema Operacional Nanvix para Arquitetura RISC-V Plataforma PULP
Authors: Oliveira Lucas S. , Nogueira Thiago H. , Freitas Henrique C.
Published: September 2022

Sistemas operacionais são desenvolvidos com o intuito de possuir a melhor otimização e funcionamento para diversas arquiteturas de processadores. A implementação é um processo delicado, já que diversas tecnologias diferentes emergem constantemente. Neste trabalho, é apresentado o desenvolvimento do port do sistema operacional Nanvix para uma arquitetura RISC-V, que vai ser emulada a partir de uma ferramenta denominada PULP SDK. Para verificar o funcionamento do port, testes automatizados foram realizados, desde o nível de kernel ao de usuário.
Die Europäische Union
Authors: Bieber Roland , Epiney Astrid , Haag Marcel , Kotzur Markus
Published: September 2022

Die Europäische Union bildet eine dynamische Rechtsordnung; jüngste Entwicklungen haben weitreichende rechtliche Implikationen:

der Umgang mit dem Ukraine-Krieg,

das Corona-Virus,

die Migrationswellen nach Europa und die Reform des Dublin-Verfahrens,

der Austritt des Vereinigten Königreich aus der EU bei zugleich weiteren Beitrittswünschen.

Die 15. Auflage des Bieber/Epiney/Haag/Kotzur stellt übersichtlich den komplexer werdenden Stoff komprimiert dar. Die wesentlichen Strukturen und Aktionsfelder der Europäischen Union (u.a. Binnenmarkt, Grundfreiheiten, Wirtschafts- und Währungspolitik, Außenbeziehungen) werden in ihrem jeweils aktuellen Entwicklungsstand und dessen Perspektiven präzise erläutert und kritisch analysiert.
Die Sportregelakzessorietät des § 265d StGB
Authors: Schramm Andreas
Published: September 2022

This paper deals with the relationship of § 265d StGB to sports law. According to this author’s opinion, the criminal liability of § 265d (1) and (2) StGB also presupposes a violation of the relevant sports rules by the beneficiary. Therefore, various questions arise, for example who is to rule on a violation of sports rules in a criminal case. In this regard, special features of competitive sport are discussed from the creation of the rules to their enforcement. Furthermore, it is examined using various examples whether sports related decisions of associations predetermine the criminal case.
Der Anfangsverdacht der Vorteilsannahme
Authors: Bauhofer Stefan
Published: September 2022

The subject of the study is the tension that has arisen between the constituent facts of Section 331 (1) of the German Criminal Code (StGB), which have escalated as a result of various amendments to the law, and the fundamental obligation of the prosecuting authorities to investigate. The existence of this conflict is demonstrated by evaluating how the executive power, judiciary and legislature deal with the offense. The latter is done through a comparative analysis of the legislative history of the bribery of elected officials, § 108e StGB. Finally, a comprehensive solution to this conflict, which is independent of individual cases, is developed in a selection of prosecutions based on criteria that are oriented toward the legal interests of criminal law.
Einstweilige Maßnahmen im Kartellverfahren
Authors: Fischer Moritz
Published: September 2022

The call for more rapid interventions by the antitrust authorities in cases of imminent harm to competition is almost as old as the antitrust authorities themselves. Especially in view of the increasingly digitalised economy, such action appears to be even more urgent. The German legislator reacted in 2021 with the revision of § 32a GWB and facilitated the imposition of interim measures by the cartel authorities. The European Commission also intends to use the instrument, which was first used in 2019 against the chip manufacturer Broadcom since its adoption in Article 8 of Regulation 1/2003, more frequently. This study explores why the instrument has so far been used so rarely and what possibilities exist to revive it.
Techniques against Distinct Abiotic Stress of Rice
Authors: Prova Ananya , Saeed Sultan Md.
Published: September 2022

Plants cannot physically escape environmental stresses because they are sessile organisms, which can stunt their growth. As a result, plants have had to evolve distinct strategies to deal with abiotic stress. Indeed, responding to and eventually adapting to abiotic stress may be a driving force in speciation. Because of the complexity of stress, multiple sensors, rather than a single sensor, are more likely to be responsible for stress perception. Stress-induced gene issues can be divided into two categories: those involved in stress tolerance and those involved in signal transduction. Stress-tolerance genes help plants cope with stress in both short- and long-term responses. These can include the synthesis of chaperones and enzymes for osmolyte biosynthesis. And, as with cold stress, detoxification causes a change in the composition of membrane lipids. Gene products can also function as transcription regulators, controlling groups of stress-related genes, or as components in the production of regulatory molecules. It has been shown that multiple signaling pathways can be activated during stress, resulting in similar responses to different triggers.
A New Method for Determination of Molecular Weight of Compounds Soluble in Protic Solvents by Electrochemical Impedance Spectroscopy
Authors: Rameshkumar Subramaniam , Karthikeyan Panjaiyan , Danaee Iman , Obulichetty Manogaran
Published: September 2022

This chapter deals with a new method for determining the molecular weight of chemical substances soluble in protic solvents. One of the well-known methods for the determination of molecular weight of a substance, based on one of the colligative properties, is Ostwald and Walker’s method, which depends on relative lowering of vapor pressure of solvent. In this paper we proposed a new method for determining the molecular mass of the substances that are soluble in protic solvents such as water, methanol and ethanol employing electrochemical impedance spectroscopy (EIS) technique and Raoult’s law. The moisture and vapor pressure dependent proton conductivity of some organic compounds and metal-organic frame works (MOFs) can be utilized to find the molecular mass of solutes soluble in protic solvents. This property is considered as key for determination of molecular weight of chemical substances using EIS and is simpler than Ostwald and Walker’s method. This method is a non-destructive and also useful to determine the molecular weight of polymers and proteins soluble in protic solvents.
The Role of Vitamin D in the Restriction of the Progress and Severity of COVID-19 Infection
Authors: Bharali Alakesh , Deka Bhargab , Sarma Himangshu , Ahmed Ashique , Bhattacharjee Bedanta , Sarma Santa , Kumar Suman , Kushari Susankar , Devi Rajlakshmi
Published: September 2022

SARS-CoV-2 has affected socio-economic activity in every country around the world since its outbreak began in 2019. 3.5 million people have died worldwide as of now, including 3.2 lakh in India. The cytokine storm significantly contributes to COVID mortality. To put it simply, the virus causes an uncontrolled release of cytokines, which results in severe inflammation, multi-organ failure, and death. Vitamin D was discovered to be a significant risk factor for cytokine storm in COVID patients. Numerous studies have demonstrated that those with deficient serum vitamin D levels have a significant mortality rate. The current understanding of the role of vitamin D in immune modulation in the innate and adaptive immune systems and how this may relate to COVID-19 is discussed in this article. Additionally, we evaluated the most recent clinical information about vitamin D deficiency, cytokine storm, and COVID-19 mortality.
Evaluation of Metallurgical Quality of Cast Iron Using Quality Criteria
Authors: Futas Peter , Pribulova Alena
Published: September 2022

The metallurgical quality of the produced cast iron is related to its chemical composition (mainly the content of C, Si, Mn, P, and S), or other monitored elements—alloying elements (Cr, Ni, Cu, …), in some cases showing elements (Pb, Sn, As, Sb, …). The chemical composition of cast iron is determined by the degree of saturation (Sc) or carbon equivalent (CE). Other factors influencing the quality of cast iron are the metallurgical conditions of production (melting and treatment) of cast iron and the rate of solidification in the mold. The mechanical properties of cast iron (Rm, HB, and E0) are closely related to its chemical composition. In addition to this common evaluation of cast iron, other quality criteria of gray cast iron are also used in practice. This is a comparison of the mechanical properties of the produced gray cast iron with the optimal values determined for the same degree of saturation (Sc). This chapter concerns assessments of the metallurgical quality of gray cast iron and the results of operational melting of synthetic gray cast iron with different charge compositions in the Slovak Foundry and its analysis.
Stem Cells in Hypertension
Authors: Kaur Randhawa Harmandeep , Khullar Madhu , Mittal Anupam
Published: September 2022

Endothelial dysfunction and vascular remodeling are the hallmarks of pulmonary arterial hypertension (PAH). For PAH treatment, there is a rising demand of Stem cell therapy. Interestingly, research reveals that stem/progenitor cells may have an impact in disease progression and therapy in PAH patients. Clinical trials for stem cell therapy in cardiac cell regeneration for heart repair in PAH patients are now underway. The clinical potential of stem/progenitor cell treatment that offers to PAH patients helps in lesion formation which occurs through regaining of vascular cell activities. Majorly the stem cells which are specifically derived from bone marrow such as mesenchymal stem cells (MSCs), endothelial progenitor cells (EPCs) and induced pluripotent cells (iPSCs), adipose-derived stem cells (ADSCs), and cardiac stromal cells (CSCs) are among the subtypes that are proved to play a pivotal role in the repair of the heart. But with only MSCs and EPCs, have shown positive outcomes and act as therapeutically efficient in regaining cure for PAH in clinical trials. This chapter also seeks to explain the potential limitations and challenges with most recent achievements in stem/progenitor cell research in PAH.
Anger, a Result and Cause of Stroke: A Narrative Review
Authors: Choi-Kwon Smi , Kim Jong S.
Published: September 2022

Post-stroke mood and emotional disturbances are frequent and diverse in their manifestations. Among them, post-stroke depression is the best known. Although post-stroke anger (PSA) has been studied relatively less, it can be as frequent as depression. Manifestations of PSA range from overt aggressive behaviors (including hitting or hurting others) to becoming irritable, impulsive, hostile, and less tolerable to family members. The possible pathophysiological mechanisms of PSA include neurochemical dysfunction due to brain injury, frustration associated with neurological deficits or unfavorable environments, and genetic predisposition. PSA causes distress in both patients and their caregivers, negatively influences the patient’s quality of life, and increases the burden on caregivers. It can be treated or prevented using various methods, including pharmacological therapies. In addition, anger or hostility may also be a risk or triggering factor for stroke. The hazardous effects of anger may be mediated by other risk factors, including hypertension or diabetes mellitus. The identification of anger as a result or cause of stroke is important because strategic management of anger may help improve the patient’s quality of life or prevent stroke occurrence. In this narrative review, we describe the phenomenology, prevalence, factors or predictors, relevant lesion locations, and pharmacological treatment of PSA. We further describe the current evidence on anger as a risk or triggering factor for stroke.
Two new bridges over the River Vardar in Skopje
Authors: Markovski Goran , Docevska Marija , Markelj Viktor
Published: September 2022

This paper presents some aspects of the design of two new bridges over the River Vardar in Skopje. "Mihajlo Apostolski" is an integral bridge, consisting of two separate structures (22.05 + 50.50 + 21.05 m = 93.6 m length and 15.3 m width). The bridge deck is made up of a two-cell prestressed cast-in-situ box girder with a parabolically variable cross section. The abutments and the piers are wall-shaped and supported on single and double row piles, respectively. The side spans, together with the approaching structures, were proposed to be built on traditional scaffolding, while the middle span over the minor riverbed was built with a free cantilever method. The extradosed bridge at Ljubljanska Street is 27.5 + 56 + 27.5 m = 111 m long and 24.1m wide. The ribbed deck (two post-tensioned main girders, cross girders, and deck slab) is supported from above by 32 parallel stay cables. The 12.6 m high pylons are located at the intermediate supports. In the base, the four piers have a rectangular cross section that has been rotated 45 degrees. The superstructure is supported by pot bearings. A deep foundation on piles was chosen. Cast-in-place construction of the superstructure was foreseen. The design of the bridges was done according to Eurocodes and respecting the fib and PTI recommendations. Detailed numerical analysis was carried out in the FEM software SOFiSTiK and additional auxiliary software.
Autoimmune comorbidities in persons with multiple sclerosis in the population of Belgrade
Authors: Marić Gorica , Tamaš Olivera , Jovanović Aleksa , Veselinović Nikola , Ivanović Jovana , Jovićević Vanja , Andabaka Marko , Ilić Miloš , Mesaroš Sarlota , Pekmezović Tatjana , Drulović Jelena
Published: September 2022

Aim of the paper: To analyze the burden of autoimmune comorbidities in persons with multiple sclerosis (PwMS) in Belgrade, Serbia, using the population-based MS Registry. Methods: A descriptive epidemiological study was used. The source of data was the Belgrade population MS Registry. The prevalence of different autoimmune comorbidities was calculated as the proportion of persons with a certain comorbidity among the total MS cohort in the Registry and presented with corresponding 95% Confidence Interval (CI). The prevalence date used was December 31st, 2021. Results: The prevalence of all autoimmune comorbidities was 5.80% (95% CI 4.98-6.73) i.e. the total of 165 autoimmune comorbidities were registered in 2841 PwMS in the Belgrade Registry on December 31, 2021. The highest prevalence was observed in autoimmune thyroid disease (4.26%, 95% CI 3.55-5.07). The highest prevalence was observed in the age groups 50-59 and 60-69 years, with higher values observed in women of all ages. Age-adjusted prevalence of autoimmune comorbidities was 0.05/100,000 in both sexes, 0.03/100,000 in males and 0.07/100,000 in females. In persons with relapsing MS phenotype prevalence of autoimmune comorbidities was 5.5%, while in persons with primary progressive MS phenotype it was 4.9%, however, this difference was not statistically significant (ch2=5.118; p=0.163). Conclusion: The results of our study showed that the prevalence of autoimmune comorbidities in PwMS in Belgrade, Serbia, is in accordance with that observed in other studies. As expected, the prevalence increased with age and was higher in females. The most common autoimmune comorbidity was the autoimmune thyroid disease.
A review of job satisfaction surveys in health care
Authors: Milošević-Gačević Marijana
Published: September 2022

The healthcare sector is one of the sectors in the EU economy with significant employment potential, which is driven by the growing demand for healthcare. Job satisfaction contributes to the improvement of the quality of service, in every profession, and it is especially important in the field of work of professionals whose service should contribute to better and more efficient health care, and therefore it has been an important research topic for a number of years. The health care sector is facing many challenges. Therefore, providing a sufficient number of well-qualified and motivated staff will be a particular problem in countries facing a marked increase in the demand for health care. It is estimated that the shortage of health workforce will reach 12.9 million health workers by 2035. The health sector of the Republic of Serbia is facing similar challenges, but it also has its own specificities, conditioned by the historical, socio-economic, cultural, and political development of the country. This paper analyses the available literature on job satisfaction, factors influencing satisfaction, and challenges for improving job satisfaction in the health sector.