bluuebunny/crossref_metadata_2025 huggingface dataset:
Spatiotemporal distribution analysis of syphilis in Brazil: Cases of congenital and syphilis in pregnant women from 2001–2017
Authors: Silva Ângelo Antônio Oliveira , Leony Leonardo Maia , Souza Wayner Vieira de , Freitas Natália Erdens Maron , Daltro Ramona Tavares , Santos Emily Ferreira , Vasconcelos Larissa de Carvalho Medrado , Grassi Maria Fernanda Rios , Regis-Silva Carlos Gustavo , Santos Fred Luciano Neves
Published: October 2022

In Brazil, the notification of congenital (CS) and syphilis in pregnant women (SiP) is compulsory. Notification data provided by the Ministry of Health in combination with the mapping of vulnerable geographic areas is essential to forecasting possible outbreaks and more effectively combating infection through monitoring. We aim to evaluate the spatiotemporal distribution and epidemiological aspects of reported cases of CS and SiP in Brazil. A retrospective ecological study was carried out using secondary surveillance data obtained from the Brazilian National Notifiable Diseases Information System (SINAN) database, considering all reported cases of CS and SiP between 2001 to 2017. Epidemiological characteristics and time trends were analyzed using joinpoint regression models and spatial distribution, considering microregions or states/macroregions as units of analysis. A total of 188,630 (359/100,000 birth lives) CS and 235,895 of SiP (6.3/100,000 inhabitants) were reported during the period studied. In general, the epidemiologic profile of Brazil indicates most reported CS cases occurred in "mixed-race" newborns who were diagnosed within seven days of birth and whose mothers had received prenatal care, but the epidemiologic profile varies by Brazilian macroregion. Regarding SiP, most cases were among women who self-reported ‘mixed-race’, were aged 20–39 years, had up to eight years of formal education and were diagnosed with primary or latent syphilis. Approximately 549 (98.4%) and 558 (100%) microregions reported at least one case of CS and SiP, respectively. From 2012 to 2016, CS cases increased significantly in almost all Brazilian states, most notably in the South, Southeast, and Central-West macroregions, from 2001–2017 and the relative risk (RR) of SiP increased around 400% (RR: 1,00 to 445,50). Considering the epidemiological scenario of the infection in Brazil, it is necessary to enhance preventive, control and eradication measures.
The relationship between objective measures of physical function and serum lactate dehydrogenase in older adults with cancer prior to treatment
Authors: Papadopoulos Efthymios , Santa Mina Daniel , Abu Helal Ali , Alibhai Shabbir M. H.
Published: October 2022

Background

Lactate dehydrogenase (LDH) reflects tumor burden and is a prognosticator of all-cause mortality in patients with cancer. Objective measures of physical function are associated with clinically relevant outcomes in older adults with cancer. However, whether physical function is associated with LDH in geriatric oncology is unknown. The objective of this study was to assess the relationship between objective measures of physical function and serum LDH in older adults with cancer prior to treatment.

Methods

Data from older adults with cancer prior to treatment were retrieved from an institutional database and medical records within a tertiary cancer centre. Physical function measures involved muscle strength and physical performance. Muscle strength and physical performance were assessed through grip strength and the Short Physical Performance Battery (SPPB), respectively. LDH was log transformed using the natural logarithm. Multivariable logistic regression was used to examine the relationship between objective measures of physical function and LDH prior to treatment in all participants. Stratified analyses were performed for participants with solid and hematological cancers.

Results

A total of 257 participants (mean age: 80.2y) were included in the analysis. Most participants were females (50.6%) and were diagnosed with locally advanced (26.8%), gastrointestinal disease (35.0%). The multivariable analysis indicated that SPPB was inversely associated with LDH in all participants (B = -0.019, 95%CI = -0.036 to -0.002, p = 0.028). Notably, the inverse relationship between SPPB and LDH persisted only in patients with hematological malignancies in the multivariable model of the stratified analysis (B = -0.049, 95%CI = -0.087 to -0.011, p = 0.013). Neither grip strength alone nor the combination of low grip strength and/or SPPB were associated with LDH. Compared to participants with metastatic disease, those with localized or locally advanced disease had lower serum LDH.

Conclusion

Physical performance is inversely associated with serum LDH in older adults with hematological cancers prior to treatment.
Stability of delay equations
Authors: Barreira Luis , Valls Claudia
Published: October 2022

For a large class of nonautonomous linear delay equations with
distributed delay, we obtain the equivalence of hyperbolicity, with the
existence of an exponential dichotomy, and Ulam–Hyers stability. In
particular, for linear equations with constant or periodic coefficients and
with a simple spectrum these two properties are equivalent. We also show
that any linear delay equation with an exponential dichotomy and its
sufficiently small Lipschitz perturbations are Ulam–Hyers stable.
Stabilization via delay feedback for highly nonlinear stochastic
time-varying delay systems with Markovian switching and Poisson jump
Authors: Li Guangjie , Hu Zhipei , Deng Feiqi , Zhang Huiyan
Published: October 2022

Little work seems to be known about stabilization results of highly
nonlinear stochastic time-varying delay systems (STVDSs) with Markovian
switching and Poisson jump. This paper is concerned with the stabilization
problem for a class of STVDSs with Markovian switching and Poisson jump.
The coefficients of such systems do not satisfy the conventional linear
growth conditions, but are subject to high nonlinearity. The aim of this
paper is to design a delay feedback controller to make an unstable highly
nonlinear STVDSs with Markovian switching and Poisson jump

H
∞

-stable and asymptotically stable. Besides, an illustrative
example is provided to support the theoretical results.
Positive solutions of a Kirchhoff–Schrödinger--Newton system with
critical nonlocal term
Authors: Zhou Ying , Lei Jun , Wang Yue , Xiong Zonghong
Published: October 2022

This paper deals with the following Kirchhoff–Schrödinger–Newton
system with critical growth

{

−
M

(

∫

Ω

|

∇
u

|

2

d
x

)

Δ
u
=
ϕ

|

u

|

2
∗

−
3

u
+
λ

|

u

|

p
−
2

u
,

i
n

 
 
Ω
,

−
Δ
ϕ
=

|

u

|

2
∗

−
1

,

i
n

 
 
Ω
,

u
=
ϕ
=
0
,

o
n

 
 
∂
Ω
,

where
Ω

⊂

R

N

(
N
≥
3
)
is a smooth
bounded domain,
M
(
t
)
=
1
+
b

t

θ
−
1

with
t
>
0
,

1
<
θ
<

N
+
2

N
−
2

,
b
>
0
,
1
<
p
<
2
,
λ
>
0

is a parameter,

2
∗

=

2
N

N
−
2

is the critical Sobolev exponent. By
using the variational method and the Brézis–Lieb lemma, the existence and
multiplicity of positive solutions are established.
New Rock Art Site at the Riverside Cliff s in the Oglakhty Mountains (Khakasia)
Authors:   Institute of Archaeology RAS, E. Miklashevich ,   “Tomskaya Pisanitsa” Kuzbass museum-reserve
Published: October 2022

The article presents the results of investigation of the rock art site discovered in 2014 on riverside rocks in the Oglakhty mountain range (Republic of Khakasia, left bank of the Yenisei River). One of the largest rock art complexes of the Minusinsk Basin is located in these mountains; the best known in archaeology are the tremendous concentrations of petroglyphs which were located on coastal cliff s before they were fl ooded by the reservoir of the Krasnoyarsk hydroelectric power station. Most of them are irretrievably lost, but some are still preserved and becoming relatively accessible in periods of lower water level. In the process of searching for and redocumenting the petroglyphs at the locations already known (Oglakhty I and II according to Ya. A. Sher’s inventory) new decorated panels have been revealed, and not only in the fl ooded levels, but also on inaccessible rocks above the highest water level. Th is new location is situated upstream from the known ones, within the southernmost section of the riverside cliff s. Several years of regular inspections of this section from a boat at various water levels and with binoculars made it possible to fi nd and document 24 panels, containing about 50 complete and partially preserved fi gures of wild animals (elk, red deer, roe deer, aurochs, arkhar, horse and others). Several stylistic groups of images are distinguished; almost all of them have analogies at known sites, which allows us to confi dently attribute them as a whole to the earliest phase of Minusinsk Basin rock art which undoubtedly predates the Bronze Age, although the specifi c period of its existence has not yet been determined.
Late Upper Paleolithic of the Lower Vitim (Based on the Data of Kovrizhka-III–IV and Bol’shoi Yakor’-I Sites)
Authors:   Irkutsk National Research Technical University, A. Tetenkin
Published: October 2022

The multilayer sites Kovrizhka-IV and Bol’shoi Yakor’-I, Kovrizhka-III (Baikal-Patom Highlands, Lower Vitim) make it possible to characterize the Late Upper Paleolithic (LUP) at the early, 19–17 Kyr BP, and late, 15–13 Kyr BC, stages, respectively. The high information potential makes it possible to highlight the culture and activities of the inhabitants in terms of lithic production and microblade splitting, living features, settling, hunting, the transportation of mineral resources from remote sources, sign-symbolic activity and art. Th e lithic assemblages of LUP appearance, in general, show continuity from the early stage to the late one. In microblade splitting, this is expressed in the translation of the Kovrizhka and Yubetsu-Bol’shoi Yakor’ techniques for preparing the wedge-shaped microcore and reducing the biface. For the early stage, chisel-shaped tools are more typical than for the late stage, for the late stage - transversal burins. On Kovrizhka-IV (early stage), the remains of dwelling features were found, art objects were discovered as well as numerous evidence of the use of ocher. Bol’shoi Yakor’-I and Kovrizhka-III (late stage) show various hearth complexes and specifi c structures made of gneiss slabs. Culturally and typologically, the LUP of the Lower Vitim correlates with the Studenovskaya culture of Southern Transbaikalia at an early stage, the Dyuktai culture of Yakutia, and the Verkholenskaya culture of Southwestern Cisbaikalia at a later stage. In the early Holocene, LUP traditions were continued in a number of sites. However, already along with the appeared complexes of the Mesolithic appearance.
Midesophageal Metastatic Disease After Treatment of Gastroesophageal Junction Adenocarcinoma
Authors: Brotherton Tim , Burton Sam , Knoche Eric , Presti Michael
Published: October 2022

Esophageal cancer carries a significant risk of morbidity and mortality because of its poor prognosis. Adenocarcinoma is the most common type of esophageal cancer in the United States. Local metastasis within the esophagus is extremely rare and likely because of the complex esophageal lymphatic system. Our patient is a 74-year-old man with adenocarcinoma of the gastroesophageal junction treated with chemotherapy and radiation who was subsequently found to have local metastasis to the proximal esophagus.
Colorectal Cancer After Screening Colonoscopy: 10-Year Incidence by Site and Detection Rate at First Repeat Colonoscopy
Authors: Schwarz Sarina , Hornschuch Michel , Pox Christian , Haug Ulrike
Published: October 2022

INTRODUCTION:

We aimed to describe cumulative colorectal cancer (CRC) incidence after screening colonoscopy stratified by tumor location, age, and sex as well as CRC detection rate at first repeat colonoscopy.

METHODS:

Using the German Pharmacoepidemiological Research Database, we included persons with screening colonoscopy and assessed cumulative CRC incidence after baseline screening colonoscopy with snare polypectomy (cohort 1) and without polypectomy (cohort 2). We also determined the CRC detection rate at first repeat colonoscopy by time since screening colonoscopy.

RESULTS:

Overall, 1,095,381 persons were included. The 10-year cumulative CRC incidence was 1.5% in cohort 1 and 0.6% in cohort 2. The proportion of proximal CRC increased with age: In women of cohort 1, 47% of CRCs in the age group 55–64 years were proximal (men: 42%) while in the age group 65–74 years, this proportion was 55% (men: 49%). In cohort 2, similar patterns were observed. In cohort 1, the CRC detection rate at first repeat colonoscopy among persons examined within 6–8 years after screening colonoscopy was more than twice as high compared with those examined within 4–6 years (1.7% vs 0.8%).

DISCUSSION:

Among persons followed up after screening colonoscopy, we observed a steadily increasing predominance of proximal CRC, and this shift showed distinct patterns by age and sex. Because our study suggests higher CRC detection rates among persons with a later repeat colonoscopy, the role of delayed surveillance and the benefit of a reminder system should be explored.
Overlapping Transcriptional Profile in Proton Pump Inhibitor Responsive and Nonresponsive Eosinophilic Esophagitis
Authors: Hamilton Matthew J. , Muftah Mayssan , Goldin Alison H. , Lo Wai-Kit , Hsu Blatman Karen S. , Chan Walter W. , Srivastava Amitabh
Published: October 2022

INTRODUCTION:

We compared esophageal mucosal gene transcript expression in proton pump inhibitor (PPI) responsive (PPI-R) eosinophilic esophagitis (EoE), PPI nonresponsive (PPI-NR) EoE, and healthy controls.

METHODS:

Transcript expression in midesophagus biopsies was determined using NanoString and a custom panel of EoE-specific genes. The top upregulated and downregulated genes with ≥2-fold difference in expression and statistically significant (P < 0.05) were identified.

RESULTS:

Nearly all the top upregulated (17 of 20) and downregulated (5 of 5) genes in EoE, compared with healthy controls, were shared between the PPI-R and PPI-NR groups.

DISCUSSION:

Esophageal mucosal transcript expressions are remarkably similar in PPI-R EoE and PPI-NR EoE compared with healthy controls.
Competências Femininas? Desvelando o agir competente na atividade de costureira
Authors: Rosa Mislene Aparecida Gonçalves , Cunha Daisy Moreira
Published: October 2022

Este artigo objetiva debater o agir competente de forma sexuada e sua atribuição às mulheres e aos homens de forma diferenciada e naturalizada de acordo com o sexo biológico. Os achados da pesquisa possibilitaram identificar e compreender o agir competente das costureiras desvelando sua complexidade.PALAVRAS-CHAVE: Relações Sociais de Sexo. Divisão Sexual do Trabalho. Abordagem Ergológica do Trabalho. Costureiras.
A Review of Computational Phantoms for Quality Assurance in Radiology and Radiotherapy in the Deep-Learning Era
Authors: Peng Zhao , Gao Ning , Wu Bingzhi , Chen Zhi , Xu X. George
Published: October 2022

The exciting advancement related to the “modeling of digital human” in terms of a computational phantom for radiation dose calculations has to do with the latest hype related to deep learning. The advent of deep learning or artificial intelligence (AI) technology involving convolutional neural networks has brought an unprecedented level of innovation to the field of organ segmentation. In addition, graphics processing units (GPUs) are utilized as boosters for both real-time Monte Carlo simulations and AI-based image segmentation applications. These advancements provide the feasibility of creating three-dimensional (3D) geometric details of the human anatomy from tomographic imaging and performing Monte Carlo radiation transport simulations using increasingly fast and inexpensive computers. This review first introduces the history of three types of computational human phantoms: stylized medical internal radiation dosimetry (MIRD) phantoms, voxelized tomographic phantoms, and boundary representation (BREP) deformable phantoms. Then, the development of a person-specific phantom is demonstrated by introducing AI-based organ autosegmentation technology. Next, a new development in GPU-based Monte Carlo radiation dose calculations is introduced. Examples of applying computational phantoms and a new Monte Carlo code named ARCHER (Accelerated Radiation- transport Computations in Heterogeneous EnviRonments) to problems in radiation protection, imaging, and radiotherapy are presented from research projects performed by students at the Rensselaer Polytechnic Institute (RPI) and University of Science and Technology of China (USTC). Finally, this review discusses challenges and future research opportunities. We found that, owing to the latest computer hardware and AI technology, computational human body models are moving closer to real human anatomy structures for accurate radiation dose calculations.
Experimental Evaluation of Thermohydraulic Performance of Tubular Solar Air Heater
Authors: Midhat Yousif Fateh , Aljubury Issam Mohammed Ali
Published: October 2022

The thermohydraulic performance of a new design solar air heater (SAH) design was examined experimentally in this paper as a trial to improve the flat-plate SAH’s efficiency. A flat-plate solar air heater (FPSAH) and a jacketed tubular solar air heater (JTSAH) having similar dimensions were constructed to compare their thermal performance efficiencies. A band of Aluminum jacketed tubes   were arranged side by side in parallel to the airflow direction to form the absorber of a jacketed tubular solar air heater (JTSAH). The experiments were accomplished at three mass flow rates (MFR)s: 0.011 kg/s. 0.033 kg/s, and 0.055 kg/s. Results revealed that the maximum temperature difference was obtained from JTSAH at 38°C in comparison to 32°C from the FPSAH at MFR of 0.011 kg/s. The thermal losses from the upper glass cover of the JTSAH were less than the same losses at the FPSAH due to the reduced absorber and glass temperatures of the JTSAH. The gained power  was higher at the JTSAH than the FPSAH. At the JTSAH, at 0.055 kg/s MFR, the maximum average thermal efficiency obtained was 81%, and the maximum average thermos-hydraulic efficiency obtained was 75.61 %. It is noted that increasing the MFR increases the thermal efficiency, also, its optimum value rises the thermos-hydraulic efficiency to a specific optimum point. The pressure drop increases with the MFR and JTSAH compared to the FPSAH
Effects of acute exercise training on tumor outcomes in men with localized prostate cancer: A randomized controlled trial
Authors: Djurhuus Sissal Sigmundsdóttir , Schauer Tim , Simonsen Casper , Toft Birgitte Grønkær , Jensen Adina Ruth Deborah , Erler Janine Terra , Røder Martin Andreas , Hojman Pernille , Brasso Klaus , Christensen Jesper Frank
Published: October 2022

Postdiagnosis physical activity is associated with improved cancer outcomes, but biological mechanisms mediating anticancer effects remain unclear. Recent findings suggest that physiological adaptations to acute exercise comprise potential anticancer effects, but these remain poorly explored in clinical settings. The objective of this study was to explore the effects of a single exercise bout on tumor oxygenation and immune cell infiltration in patients with prostate cancer. Thirty patients with localized prostate cancer were randomized (2:1) to either one high‐intensity interval training bout or no exercise on the day before radical prostatectomy. Immunohistochemical analyses were performed on prostatic tissue from surgery and assessed for tumor hypoxia, natural killer (NK) cell infiltration, and microvessel density (MVD). Acute systemic response in blood lymphocytes, epinephrine, norepinephrine, IL‐6, tumor necrosis factor, cortisol, lactate, and glucose was also evaluated. We did not find between‐group differences in tumor hypoxia (Mann–Whitney U test, U = 83.5, p = 0.604) or NK cell infiltration (U = 77.0, p = 0.328). Also, no significant correlation was found between MVD and tumor hypoxia or NK cell infiltration. One exercise bout is likely insufficient to modulate tumor hypoxia or NK cell infiltration. Future studies may elucidate if an accumulation of several exercise bouts can impact these outcomes (NCT03675529, www.clinicaltrials.gov).
Synthesis of newer substituted chalcone linked 1,2,3-triazole analogs and evaluation of their cytotoxic activities
Authors: Raghavender Matta , Shankar Bhookya , Umapathi Nalla , Jalapathi Pochampally
Published: October 2022

An innovative heterocyclic biologically active chalcone 1,2,3-triazole analogs (6a–j) were prepared to extract excellent yields by coupling the substituted aryl azides (5a–5j) and 5-ethynyl-1,2,3-trimethoxybenzene, by using the method of Huisgen azide–alkyne cycloaddition. The typically synthesized analogs were elucidated by IR, 1H-nuclear magnetic resonance (NMR), 13C-NMR, and Electron spray ionization (ESI)-mass spectroscopy and tested for their cytotoxicity effectiveness in MTT assays against the A549 lung cancer cells. The cytotoxic studies suggested that a few analogs showed moderate to good activities. The compounds 6i and 6c showed low cytotoxicity against the A549 cell line among 12 analogs, the values of IC50 were displayed in the range of 65.05 ± 1.12 and 71.56 ± 1.29 µM, respectively. The compound 6j showed slightly less cytotoxicity but showed good selectivity against A549 cell lines.
Iterative learning control for conformable stochastic impulsive differential systems with randomly varying trial lengths
Authors: Qiu Wanzheng , Fečkan Michal , Wang JinRong , Shen Dong
Published: October 2022

In this paper, we introduce a new kind of conformable stochastic impulsive differential systems (CSIDS) involving discrete distribution of Bernoulli. For random discontinuous trajectories, we modify the tracking error of piecewise continuous variables by a zero-order holder. First, the improved P-type and PD

α
-type learning laws of the random iterative learning control (ILC) scheme are designed through global and local averaging operators. Next, we establish sufficient conditions for convergence of the tracking error in the expectation sense and prove the main results by using the impulsive Gronwall inequality and mathematical analysis tools. Finally, the theoretical results are verified by two numerical examples, and the tracking performance is compared for different conformable order of α.
Discussion on controllability of non-densely defined Hilfer fractional neutral differential equations with finite delay
Authors: Kavitha Krishnan , Vijayakumar Velusamy
Published: October 2022

This manuscript prospects the controllability of Hilfer fractional neutral differential equations. The new results are obtained by implementing a suitable fixed point approach and the technique of measures of noncompactness and the outcomes and facts belong to fractional theory. Firstly, we focus the controllability and extend the discussion with nonlocal conditions. Finally, an interesting example is proposed to illustrate our main obtained results.
Modeling and PID control of quadrotor UAV based on machine learning
Authors: Zhou Lirong , Pljonkin Anton , Singh Pradeep Kumar
Published: October 2022

The aim of this article was to discuss the modeling and control method of quadrotor unmanned aerial vehicle (UAV). In the process of modeling, mechanism modeling and experimental testing are combined, especially the motor and propeller are modeled in detail. Through the understanding of the body structure and flight principle of the quadrotor UAV, the Newton–Euler method is used to analyze the dynamics of the quadrotor UAV, and the mathematical model of the UAV is established under the small angle rotation. Process identifier (PID) is used to control it. First, the attitude angle of the model is controlled by PID, and based on this, the speed in each direction is controlled by PID. Then, the PID control of the four rotor aircraft with the center of gravity offset is simulated by MATLAB. The results show that the pitch angle and roll angle can be controlled by 5 degrees together without center of gravity deviation, and the PID can effectively control the control quantity and achieve the desired effect in a short time. Classical BP algorithm, classical GA-BP algorithm, and improved GA-BP algorithm were trained, respectively, with a total of 150 sets of training data, training function uses Levenberg-Marquardt (trainlm), and performance function uses mean squared error (MSE). In the background of the same noise, the improved GA-BP algorithm has the highest detection rate, classical GA-BP algorithm is the second, and classical BP algorithm is the worst. The simulation results show that the PID control law can effectively control the attitude angle and speed of the rotor UAV in the case of center of gravity deviation.
Generalized Munn rings
Authors: Guo Junying , Guo Xiaojiang
Published: October 2022

Generalized Munn rings exist extensively in the theory of rings. The aim of this note is to answer when a generalized Munn ring is primitive (semiprimitive, semiprime and prime, respectively). Sufficient and necessary conditions are obtained for a generalized Munn ring with a regular sandwich matrix to be primitive (semiprimitive, semiprime and prime, respectively). Also, we obtain sufficient and necessary conditions for a Munn ring over principal ideal domains to be prime (semiprime, respectively). Our results can be regarded as the generalizations of the famous result in the theory of rings that for a ringRR,RRis primitive (semiprimitive and semiprime, respectively) if and only if so isMn(R){M}_{n}\left(R). As applications of our results, we consider the primeness and the primitivity of generalized matrix rings and generalized path algebras. In particular, it is proved that a path algebra is a semiprime if and only if it is semiprimitive.
Imitation of human muscle by using an electromechanical system
Authors: Ünal Engin , Özcan Samet
Published: October 2022

Humanity is increasingly approaching the dream of making humanoid robots that have been imaginary for many years with advancing technology. Designs that are close to perfect in humanoid or animal-like robots emerge with the research and development studies carried out by researchers on this subject. In order to develop these robots, the movement mechanism of humans and animals must be examined again. Robots will work in place of people and can be used in wars with the development of these systems. In this study, the usability and performance of the linear actuator, which is widely used in various mechatronic systems as a linear motion provider, in the artificial muscle mechanism have been tested. Moreover, it tried to create a similar prototype by examining the working logic of skeletal muscle. The different aspect of the study is to indicate how the motion energy can be gained without using the conventional motors that are used in robot technologies. The artificial musculature is formed by arranging the electromagnets in a row, leaving a gap between them. The desired length of movement is formed as a result of the activated electromagnets gaining magnetism and closing the gap. In the study, the maximum load that the artificial muscle can pull according to the given voltage was 130.18 N and the average maximum gap length of each sarcomere was 1.68 mm. The efficiency of artificial muscle was found to be 56% compared to human muscle.
Earing prediction of 2090-T3 aluminum-cups using a complete homogenous fourth-order polynomial yield function
Authors: Firat Mehmet , Şener Bora , Akşen Toros Arda , Esener Emre
Published: October 2022

Earing can be described as difference in cup wall height due to planar anisotropy of the sheet metals, and both prediction and minimization of this defect are critical steps of drawing process design to save material and production costs due to additional trimming operations. The finite element (FE) method is a practical design tool in this context. The accuracy of FE analyses is directly dependent on modeling material deformations using an effective plasticity model. In this study, a homogeneous orthotropic fourth-order polynomial stress function is presented and implemented into Ls-Dyna FE software by a user-defined material subroutine to predict the earing evolution of a strongly anisotropic aluminum alloy (AA2090-T3) in cup drawing. Primarily, the parameters of the function were calibrated using test data. The effects of element size, number of through-thickness integration points, and time-step size were investigated separately on the drawn cup’s earing profile and thickness strain distributions. It was observed that mass scaling factor related to time step size has a significant impact on the cup height and profile. Finally, simulations were repeated with optimum parameters to assess the performance of the plasticity model. The yield criterion successfully predicted the cup profile, earing amplitude, and thickness strain distributions.
Role of semiconductor photo catalysts on mask pollution management
Authors: Karthikeyan Balakrishnan , Therasa Alphonsa Antonybaburajan , Vijayakumar Natesan , Vinoth Raja Antony Samy Jose
Published: October 2022

Covid 19 pandemic taught us many lessons. Wearing mask becomes an essential to save our lives. At the same time, management of mask wastages is becoming threat to the environment as they release harmful dyes and fibres. Here in this work we attempt to degrade the mask dyes from the surface of the mask using nano metal oxide based silicate photo catalysts. Two nanocomposites PbO-SiO2
and TiO2-SiO2
were studied on the degradation of coloured mask. The percentage degradation was found to be more than 90%. The results are encouraging so that the proposed catalysts can be used for coating on the masks or used as photo catalyst to degrade the used masks.
Influence of Reverted Austenite on Tensile Deformation and Fracture in 18Ni 250 Maraging Steel
Authors: Rohit Benjamin , Muktinutalapati Nageswara Rao
Published: October 2022

Overaging of C250 maraging steel leads to reversion of austenite. The percentage of reverted austenite in the microstructure increases with an increasing extent of overaging. The effect of volume fraction of reverted austenite on the deformation behavior during tensile testing was studied. Specimens in the solution-annealed condition of the steel were overaged using different temperature/time combinations to produce a range of reverted austenite volume fractions. Changes in the lattice parameter of the martensite phase as a function of overaging treatment were monitored. X-ray diffraction technique was used to measure the volume fraction of reverted austenite and monitor the changes in lattice parameter of martensite. True stress–true strain curves were calculated from the engineering stress–engineering strain diagrams obtained for different overaging treatments, and plots showing the rate of work hardening as a function of true strain were derived. The present investigation shows that the reverted austenite produced at 538°C and 620°C induces serrated flow during tensile testing, whereas reverted austenite produced at 510°C does not. It is believed that the reverted austenite formed at the two higher temperatures is not stable because of the relatively lower amount of nickel and transforms to martensite on tensile deformation, leading to serrated flow. After aging at 510°C and 538°C, after the initial steep drop in the work hardening rate, the rate remains nearly constant over a certain range of true strain before it starts dropping again. After aging at 620°C, in contrast, the work hardening rate continuously decreases with increasing true strain. The precipitates formed after aging at 510°C/538°C are believed to be important contributions to the occurrence of the plateau. The results show that not only the quantity of reverted austenite but also the temperature at which reversion took place influence the fracture mechanisms and fracture surface appearance.
The direct STAT3 inhibitor 6-ethoxydihydrosanguinarine exhibits anticancer activity in gastric cancer
Authors: Liu Xuewen , Jin Xin , Ou Hongling , Qian Chen , Wu Hui , Zuo Chunmei , Ren Yuliang , Fu Miaoxin , Zhang Te , Zhang Liang , Si Yuan , Liu Ying
Published: October 2022

Signal transducer and activator of transcription 3 (STAT3) plays a key role in promoting tumor malignant progression. Suppression of hyperactivated STAT3 signaling has emerged as a potential therapeutic strategy for many cancer types. In this study, the effect of 6-ethoxydihydrosanguinarine (6-EDS), a secondary transformation product formed from dihydrosanguinarine, isolated from Macleaya (Papaveraceae), was evaluated in gastric cancer (GC). We demonstrated that 6-EDS inhibited the survival, migration, and invasiveness of GC cells in vitro. Moreover, 6-EDS inhibited STAT3 phosphorylation and transcriptional activity, thus suppressing the mRNA expression of downstream target genes associated with the malignant survival, migration, and invasiveness of GC cells. Molecular docking indicated that 6-EDS directly bound the SH2 domain of STAT3. Molecular dynamics simulations suggested that 6-EDS inhibited the binding of phosphorylated and non-phosphorylated STAT3 to target DNA. Cellular thermal-shift assays and microscale thermophoresis further confirmed the direct binding of 6-EDS to STAT3. Site-directed mutagenesis indicated that the S611 residue in the SH2 domain of STAT3 is critical for 6-EDS binding. In vivo, 6-EDS decreased tumor growth in xenografted nude mice by blocking STAT3 signaling. These findings indicated that 6-EDS, a direct STAT3 inhibitor, may be a potent anticancer candidate for GC therapy.
Gardien de l’équilibre et du dynamisme : un rôle à assumer par le leadership municipal pour le développement d’un écosystème entrepreneurial
Authors: Grandbois Valérie , Lalonde Jean-François , Tombet-Moupegnou Constantin , Paquet Jean-Frédéric
Published: October 2022

Le rôle important des gouvernements locaux pour le dynamisme des écosystèmes entrepreneuriaux est reconnu. Notre étude porte sur le rôle du leadership municipal et des institutions publiques dans le développement et le maintien d’écosystèmes entrepreneuriaux dynamiques en prenant en considération les caractéristiques locales. Trois écosystèmes entrepreneuriaux sont étudiés : Shawinigan, Trois-Rivières et Sherbrooke, au Québec. Nous avons colligé nos données à l’aide de sondages, d’entrevues et d’observations. Nos résultats montrent qu’un leadership municipal clair, assumé et concerté stimule le désir de transformation et alimente le changement de culture parfois requis au sein des écosystèmes. Les villes jouent un rôle fédérateur entre les différents acteurs de l’écosystème. Elles sont les gardiennes d’un point d’équilibre à atteindre entre centralisation et décentralisation : une mutualisation qui s’articule autour de la volonté de collaboration entre les acteurs, du constat d’un besoin d’optimisation des ressources et de l’existence de projets fédérateurs.
L’apport des arts et de la culture au développement des écosystèmes entrepreneuriaux : le cas du hub territorial Avantage numérique
Authors: Labrecque-Denis Maude , L'Écuyer François , Vézina Cathy
Published: October 2022

La créativité stimule l’innovation (Wolfe, 2007); elle joue ainsi un rôle important dans le développement économique à l’ère numérique. Le milieu des arts et de la culture, passé maître dans la pratique créative, apparaît dès lors comme une composante clé des écosystèmes entrepreneuriaux (ÉE). Dans un contexte où la transition numérique des collectivités dépend de la transversalité sectorielle (Caron et collab., 2020), nous nous intéressons aux apports du milieu des arts et de la culture dans le développement des ÉE. À travers une étude de cas basée sur l’évolution d’un projet de hub créatif, nous préciserons les dynamiques à l’oeuvre dans la structuration intersectorielle des ÉE. Ce faisant, nous ouvrirons la réflexion sur les notions d’innovation ouverte, de créativité et de codéveloppement à l’ère numérique.
Saint-Jean-Eudes une communauté en transition sociale et écologique : le cas d’un quartier ouvrier à Saguenay
Authors: Tremblay Suzanne
Published: October 2022

Saint-Jean-Eudes est un quartier situé à la limite des arrondissements de Chicoutimi et de Jonquière, à Saguenay. Enclavé entre l’usine de Rio Tinto et la rivière Saguenay, il a subi de nombreux changements au cours des dernières années. Puisqu’il est l’un des derniers quartiers de Saguenay à avoir conservé les caractéristiques d’un secteur ouvrier jusqu’aux années 2000, il constitue un cas d’intérêt pour étudier et comprendre les transformations d’un quartier ouvrier. Ce texte présente les résultats d’une recherche qualitative effectuée dans la perspective de la sociologie urbaine. L’étude permet d’observer comment les changements sociaux et économiques survenus au cours des dernières décennies ont modifié les rapports sociaux dans ce territoire urbain et ont transformé les modes de vie des habitants ainsi que les perceptions de l’environnement industriel du quartier.
Analyse géographique des investissements publics nationaux en innovation au Canada et implications pour les écosystèmes entrepreneuriaux régionaux
Authors: Rajaonson Juste , Poulin Pier-Olivier , Pronovost Stéphane
Published: October 2022

Cet article présente une analyse de la distribution spatiale des investissements en innovation du gouvernement du Canada dans diverses régions et collectivités du pays. La démarche proposée consiste à exploiter les données ouvertes du Programme de divulgation proactive des renseignements du gouvernement du Canada. Au total, 39 419 entrées valides représentant 10,8 milliards de dollars de subventions et de contributions octroyées de 2018 à 2020 sont analysées. À l’aide de statistiques descriptives, nous comparons les montants octroyés dans les provinces, les grandes agglomérations urbaines et leurs zones d’influence. Nous montrons notamment que les plus grandes métropoles du pays attirent la plus grande part des investissements en innovation par habitant. En dehors des métropoles, le soutien public à l’innovation est plus faible et cette différence par rapport aux métropoles est statistiquement significative. Ces observations ont des implications pour la recherche sur l’attraction d’investissements publics en innovation dans les écosystèmes entrepreneuriaux des milieux ruraux.
Le Plan d’implantation et d’intégration architecturale (PIIA) et ses effets au cœur des préoccupations des résidents de la Cité-Jardin du Tricentenaire à Montréal
Authors: Paré Sylvie , Dupont Kévin
Published: October 2022

La Cité-Jardin du Tricentenaire, une enclave résidentielle située près du stade olympique dans l’est de Montréal, est témoin d’un renouvellement de sa population et de son marché immobilier. Depuis environ 25 ans, on y observe une importante augmentation de la valeur des propriétés du quartier qui est liée aux transformations sociodémographiques, économiques, mais aussi architecturales. Depuis son adoption en 2009, le Plan d’implantation et d’intégration architecturale (PIIA) constitue un outil d’urbanisme encadrant les travaux que ses résidents et résidentes souhaitent apporter à leur propriété. Or, les incidences de la mise en oeuvre de cet outil d’urbanisme préoccupent certains des résidents, ce qui conduit à l’émergence de visions presque antagonistes entre les anciens et les nouveaux. Afin de mieux comprendre et de saisir ces différences, nous avons mené une enquête auprès de l’ensemble des résidents et résidentes de la Cité-Jardin en 2019. Cet article présente donc le contexte de mise en place du PIIA ainsi que les résultats de notre enquête.
Jesús Pena (1947-2021)
Authors: Mariño Ramón , Rio-Torto Graça
Published: October 2022

O día 28 de outubro de 2021 faleceu o profesor Jesús Pena, catedrático da área de Lingua española da USC e membro do Consello de Redacción da revista Verba entre os anos 1991 e 2010.

Ramón Mariño, secretario primeiro e director despois da revista, rememora a súa relación persoal co mestre e co amigo.

Graça Rio-Torto, da Universidade de Coimbra, amiga e morfóloga como Jesús, evoca a súa traxectoria académica e lembra ao compañeiro e amigo que nos deixou.
Estado y luchas de clases en Brasil (2019-2021)
Authors: Folena de Oliveira Jorge Rubem
Published: October 2022

El objetivo del presente ensayo es analizar la actuación de la clase dominante en Brasil, que busca implementar el proyecto ultraliberal de desconstrucción del Estado de bienestar social, así como de los derechos humanos y ambientales
Danzas nicaragüenses en tiempo de crisis 2019: a un año de los levantamientos ciudadanos
Authors: Jarquín-Madriz Lucía , Oporta- Herrera Fred
Published: October 2022

El articulo presenta una interpretación de los levantamientos cívicos en Nicaragua iniciados el 18 de abril de 2018, a través de la danza. Estas acciones se analizan desde cinco momentos claves desarrollados desde la panorámica del Colectivo Sinergia así como desde la interpretación de los autores desde la expresión corporal en relación a los actos violentos del gobierno nicaragüense contra las personas. Para ello se toma como insumo una serie de entrevistas anónimas realizadas a las personas víctimas de esta nueva realidad.
Mario Oliva, su legado
Authors: Mora-Rodriguez Arnoldo
Published: October 2022

En días recientes falleció un gran intelectual y dilecto amigo, catedrático de  la UNA, Mario Oliva Medina. De origen chileno, vino a Costa Rica muy joven a consecuencia del golpe de estado fascista perpetrado por una junta militar presidida por el General Augusto Pinochet; estudió en la UNA en donde obtuvo la licenciatura en historia y luego el doctorado en Pensamiento y Cultura Latinoamericana; allí mismo ejerció como docente e investigador en el Instituto de Estudios Latinoamericanos (IDELA)

 

Publicado originalmente en: https://semanariouniversidad.com/suplementos/loslibros/mario-oliva-su-legado/
Tributo a Mario Oliva Medina: latinoamericano martiano
Authors: Rodriguez Pedro Pablo
Published: October 2022

Desde 1984 impartió cátedra en los programas de licenciatura, maestría y doctorado en Estudios Latinoamericanos y pensamiento latinoamericano en la Facultad de Filosofía y Letras de su Universidad; ejerció como vicerrector de Extensión de la Universidad Nacional de2010 a 2015; y durante los cinco años siguientes dirigió el Instituto de Estudios Latinoamericanos de ese centro de educación superior.

 

Publicado originalmente en: http://www.josemarti.cu/tributo-a-mario-oliva-medina-latinoamericano-martiano/
Crónicas del exilio: Mario Oliva Medina in memoriam
Authors: Cedeño-Castro Rogelio
Published: October 2022

La dialéctica implacable o ineludible entre esos dos puntos extremos que los seres humanos llamamos vida y /o muerte nos confronta, de manera inevitable, con lo efímero y pasajero de nuestra condición humana, pero también con el sentido mismo de la existencia de nosotros los humanos, en el caso de que de verdad lo tenga, como unas afirmaciones en voz alta que vienen a ser el sustrato de una serie de reflexiones y sentimientos que acuden en tropel a nosotros, o que más bien fluyen desde el interior de nuestra conciencia cuando el deceso de un amigo muy querido sacude nuestra aparente tranquilidad exterior.

 

Publicado originalmente en: https://surcosdigital.com/cronicas-del-exilio-mario-oliva-medina-in-memoriam/
El valor de la investigación en las humanidades
Authors: Quiroz Ávila Ruben
Published: October 2022

Hay una competencia desigual en la carrera por las publicaciones científicas. Incluso más allá del concepto neopositivista aún erradamente vigente que iguala lo científico a la exclusiva y excluyente producción científica de las ciencias básicas, minimizando toda producción humanística. Para ello, han montado un aparato de control de los organismos que van definiendo tanto las políticas como la ejecución de ellas. Se castiga el sistema habitual de los que nos dedicamos a las humanidades sin reconocer las diversas formas que adopta nuestra producción intelectual como comunidad de investigadores en ciencias humanas.
El personaje de frontera en País de Jauja de Edgardo Rivera Martínez y Ximena de dos caminos de Laura Riesco
Authors: Jurado Urbina Brayan Jayro Aloysius
Published: October 2022

El presente artículo propone una lectura de las novelas País de Jauja de Edgardo Rivera Martínez y Ximena de dos caminos de Laura Riesco, desde la noción de personaje de frontera. Este es definido como el sujeto que busca la integración de los diferentes sistemas socioculturales representados en las obras. En el caso particular de ambas novelas, se referirá lo andino y lo occidental. Para ello, nos apoyaremos en la propuesta de Yuri Lotman sobre la semiosfera, la cual nos permitirá reconocer los elementos simbólicos que definen a ambas culturas. El reconocimiento de estos personajes de frontera pondrá en evidencia una marcada tendencia conflictiva que desvirtúa todo proceso conciliador entre lo andino y lo occidental. A partir de esto, reconoceremos cómo ambos proyectos narrativos se vinculan en una reflexión mayor que plantea la reformulación de la identidad cultural andina como resultado de su interacción con lo occidental.
Filosofía del derecho constitucional: análisis de las resoluciones del Consejo Nacional de la Magistratura, hoy Junta Nacional de Justicia (JNJ)
Authors: Zelada Flores Jaime Alejandro
Published: October 2022

Los factores sociales influyen en la evolución del derecho constitucional. Sin embargo, la filosofía del derecho constitucional, al hacer un estudio racional de la normativa, en un contexto social-universal, propone alternativas en la búsqueda de soluciones. En ese escenario se realiza este trabajo de investigación sobre el Tribunal Constitucional y la interpretación de las resoluciones emitidas por el Consejo Nacional de la Magistratura (CNM) en materia de evaluación y ratificación de magistrados, mediante el análisis de las resoluciones del Consejo Nacional de la Magistratura, hoy Junta Nacional de Justicia ( JNJ), dentro de un contexto sociojurídico. Al respecto, el artículo 142 de la Constitución de 1993 regula que: “No son revisables en sede judicial las resoluciones del Jurado Nacional de Elecciones, en materia electoral, ni las del Consejo Nacional de la Magistratura en materia de evaluación y ratificación de jueces”. Sin embargo, el Tribunal Constitucional interpretó que es factible la interposición y declaración como fundada de una demanda de amparo contra el CNM. En ese sentido y luego de realizar el estudio de las sentencias expedidas, sobre este particular, se observa que la labor de interpretación realizada excede los límites de esta institución y es, por tanto, apropiada la reforma constitucional.
Guillermo Joo Muñoz. Flor Pucarina. Hasta siempre... Huancayo, Fondo Editorial de la Municipalidad Distrital de Pucará, 2020. 120 pp.
Authors: Pérez Luna Julio
Published: October 2022

¿Quién es Flor Pucarina? Es la cantante popular más exitosa de la historia fonográfica peruana. No obstante, tal vez usted nunca ha escuchado su música, debido a esa barrera cultural que existe entre el “Perú oficial” y “el otro Perú”, como decía el antropólogo José Matos Mar en su Desborde popular y crisis del Estado (1984). O, quizás, sí y hasta la idolatra, pero igual, posiblemente, no sabe quién es. La intérprete, también llamada la Faraona del Cantar Huanca, ya es un mito, un personaje de leyenda, y, como tal, su vida —o lo que se cuenta de ella— es una mezcla de realidad y ficción. Se sabe, por ejemplo, que su canción “Ayrampito”1 vendió un millón de copias hacia la mitad de la década de 1960 y que cuando murió, el 5 de octubre de 1987, una multitud que cubría aproximadamente 10 cuadras del Centro de Lima llevó su ataúd hasta el cementerio El Ángel. Pero también se ha dicho que era una libertina, que “había ejercido la prostitución” —en octubre de 2017, las protestas de habitantes y autoridades del valle del Mantaro provocaron que el diario La República, medio que publicó esta información, se disculpara y eliminara el artículo de su plataforma web—, que su fantasma sigue pululando por los bares de La Victoria y que soñar con ella trae buena suerte. La leyenda es tal que incluso su nombre de nacimiento ha generado contradicciones entre sus más aplicados cronistas (muchos creen que es Leonor Chávez Rojas, como figura en su lápida).