bluuebunny/crossref_metadata_2025 huggingface dataset:
Hormonal influences on women’s extra-pair sexual interests: The moderating impact of partner attractiveness
Authors: Dinh Tran , Thompson Melissa Emery , Gangestad Steven
Published: November 2022

Based on the idea that women are especially attracted to ancestral markers of male genetic quality when conceptive in their cycle, scholars have conjectured that increases in women’s extra-pair sexual interests during the conceptive phase of the cycle are moderated by their primary partners’ sexual attractiveness. Multiple studies have examined this prediction, with largely supportive but mixed results. The current study is the first to examine whether hormonal influences—thought to mediate cycle shifts—on women’s extra-pair sexual interests are moderated by partner attractiveness. 213 naturally cycling, romantically involved women (181 attending multiple sessions) participated in up to four sessions over about a month. Estrogen and progesterone levels were measured multiple times across women’s cycles. Male partner attractiveness moderated associations between progesterone levels (though not estrogen levels) and women’s extra-pair sexual interests. A negative association between progesterone levels and extra-pair sexual interests, a composite measure, was observed for women with relatively unattractive partners. For women with relatively attractive partners, no clear association emerged. The interaction between progesterone and partner attractiveness was robust for women’s interest in extra-pair sex, a component preregistered as exploratory. The interaction effect was also significant for the absolute intensity of women’s extra- pair attraction (a component item referenced in the preregistration) but was non-significant for the frequency of women’s extra-pair attraction relative to typical days (a composite component specified in the preregistration). These findings inform theoretical understandings of women’s sexuality.
Chinese Psychology of Religion: Eastern Traditions
Authors: Chen Zhuo Job
Published: November 2022

This chapter will focus on Eastern traditions including Buddhism, Daoism, Confucianism/syncretism, and folk religions. Buddhism, being originally from India, has been a staple religion among both Han people devoted to various schools of Mahayana Buddhism, and Tibetans, including adjacent ethnicities such as Mongolians and Tu, devoted to various schools of Vajrayana Buddhism. Daoism, by contrast, was originally a Han religion and has arguably shaped, as well as being shaped by, the fundamental Chinese way of thinking. Confucianism is as much a national philosophy as a religion and, syncretizing with Buddhism and Daoism, its influence ranges from defining what an ideal person is to how a society should be governed. The picture of folk religions is much more complex – multiple layers of folk beliefs and practices permeate Chinese lives running the gamut of fengshui, ancestor worshiping, and believing in gods without any official affiliation. This chapter selects key literature from both mainland China (database for Chinese publications is at cnki.net) and Taiwan (airitilibrary.com). Many of the literature reviewed are published in Chinese which the authors read as native speakers. It is our intention to present an insider’s view of what Chinese psychology of religion is like from within its cultural context.
Regulatory and Policy Frameworks for Offshore Wind Projects: Spatial and Temporal Considerations in Light of Fisheries Sustainability amid Climate Change
Authors: Arif Abdullah Al , Anchustegui Ignacio Herrera
Published: November 2022

This article explores the interplay between offshore wind projects (OWPs) and fisheries within a climate change context. There is scant literature reviewing the interaction and regulatory framework that applies or ought to apply to these two uses of the sea. We attempt to fill the gap by critically examining the relationship between OWPs, fisheries and climate change to then identify the key challenges arising from their interaction and co-existence. These issues not only slow down the deployment of offshore wind projects but also put in perspective the consequences of such projects. Advancing the state of the art, we put forward broad regulatory suggestions based on science-policy interfaces and marine planning concerning the spatial and temporal factors of OWPs to achieve the peaceful and sustainable co-existence of two essential resources – offshore wind and fisheries.
Untapped Potential: Designed Digital Trace Data in Online Survey Experiments
Authors: Macke Erin , Daviss Claire , Williams-Baron Emma
Published: November 2022

Researchers have developed many uses for digital trace data, yet most online survey experimentscontinue to rely on attitudinal rather than behavioral measures. We argue that researchers cancollect digital trace data during online survey experiments with relative ease, at modest costs,and to substantial benefit. Because digital trace data unobtrusively measure survey participants’behaviors, they can be used to analyze digital outcomes of theoretical and empirical interest,while reducing the risk of social desirability bias. We demonstrate the feasibility and utility ofcollecting digital trace data during online survey experiments through two original studies. Inboth, participants evaluated interactive digital resumes designed to track participants’ clicks,mouse movements, and time spent on the resumes. This novel approach allowed us to betterunderstand participants’ search for information and cognitive processing in hiring decisions.There is immense, untapped potential value in collecting digital trace data during online surveyexperiments and using it to address important sociological research questions.
Reporte de caso clínico: Esófago-Gastro-Pexia-Cervical por Estenosis Esofágica Secundaria a Ingesta de Cáusticos
Authors: Villacis Raúl , Aulestia David , Haro Hugo , Arias Grace , Vasconez Nicole
Published: November 2022

Introducción: La estenosis esofágica causada por la ingesta de sustancias corrosivas o por cáusticos, es la atrofia o estrechez del esófago debido al daño que causan estas sustancias en los tejidos, es considerado intolerable en el paciente y en ciertos casos  puede causar hasta la muerte. El daño puede ser reversible o irreversible por lo que realizar un correcto diagnóstico nos conlleva a un tratamiento adecuado y eficaz. La estenosis por esta etiología se produce principalmente en el tercio superior del esófago.
Objetivo: Describir un caso clínico de estenosis esofágica con manejo de esófago gastro pexia cervical.
Material y métodos: Estudio descriptivo retrospectivo presentación de caso clínico.
Resultados: Se presenta al caso de una  paciente de 22 años que acude al área de emergencia del Hospital de Especialidades Eugenio Espejo con antecedente de ser portadora de yeyunostomia por estenosis esofágica por ingesta de cáusticos desde hace 3 años que fue sometida a una esófago gastropexia cervical con adecuada evolución post quirúrgica con mejora de su estado nutricional y habilitada completamente la vía oral así como una reinserción pronta a su vida personal y social con buenos resultados.  
Conclusiones: Las quemaduras esofágicas por ingesta de cáusticos son frecuentes por lo tanto el galeno debe tener en cuenta que el tratamiento quirúrgico para estenosis esofágica está indicado cuando las dilataciones no son efectivas, cuando se producen perforaciones o cuando el riesgo de perforación es alto y también ante la necesidad de mejorar la calidad de vida de estos pacientes obligados a dilataciones esofágicas periódicas y/o a alimentarse por gastrostomía o yeyunostomia de igual forma con cuadro de desnutrición moderada a grave, hacen un reto el manejo de esta patología como vimos en el presente caso.
No existe un consenso sobre cual técnica quirúrgica es la mejor, ya que tanto la esofagogastroplastia como la esofagocoloplastia tienen sus ventajas y desventajas, sin embargo el galeno deberá estar en la capacidad para decir sobre cuál es la mejor para su paciente. En nuestro caso Se optó por la Esófago gastro pexia cervical con un adecuada evolución post quirúrgica e inserción a su vida cotidiana personal y social con adecuada mejora de su nivel nutricional y sobretodo habilitada la vía oral.
End of Life Care : Challenges in Nepal
Authors: Sapkota Sulav , Priyadarshini Mona
Published: November 2022

N/A
Functional outcome of column specific fixation in the management of complex tibial plateau fractures
Authors: Thapa Bishwamber , Sitoula Prakash , Jha Ranjib , Thapa Santosh
Published: November 2022

Introduction: Complex tibial plateau fractures usually have complicated intra-articular fracture pattern, often associated with severe soft tissue injury and high risk of wound complications. Single or dual column plating fixation principle based upon conventional x-ray for such fractures may not address multiplanar comminution that  often has posterior shearing or  coronal fractures. Computed tomography based evaluation of such fractures  and column specific  approach allow direct fracture visualization and anatomic reduction  that results in satisfactory outcome.

Objectives: To assess the clinical and functional outcome and complications of complex tibial plateau fractures fixed with column specific fixation principle.

Methodology: This prospective study was carried out from September 2019 to August 2021 in Orthopaedic department of Nobel Medical College, Biratnagar. Consecutive sampling was used among patient with complex tibial plateau fractures meeting the inclusion criteria. Among 30 patients, with  closed and Gustilo grade I or II Schatzker type V-VI fractures or AO type-C injuries to the proximal tibia were operated on column specific approach and followed up for clinico-radiological evaluation.

Results: In this study, most of the patients belonged to 31-40 years of age group with mean age of 40.47 years. Majority of patients were male( 76.7%). Fracture was highly associated with road traffic accident which accounted for 83%. Fourteen patients underwent anteromedial and anterolateral plating(46.67%), 10 patients underwent anterolateral and posteromedial plating(33.33%) and remaining 6 patients underwent triple column plating(20%). The Rasmussen’s functional score at final follow up was  27.17±2.793(range 21-30). 86.7% patients had acceptable clinical outcome. The mean Rasmussen’s radiological score at final follow up was 8.97±1.217(range 6-10). Thus 93.4% patients had acceptable radiological outcome.

Conclusion: Column specific approach addresses all the fracture fragments of complex tibial plateau fractures to achieve acceptable clinical and radiological outcome.
Gestational Trophoblastic Neoplasia: A Clinico-Epidemiological Profile In A Tertiary Care Hospital
Authors: Das Indrani , Mandal Payel , Samanta Sandip , Mistri Pallab Kumar , Kyal Amit , Mukhopadhyay Partha
Published: November 2022

Introduction: Gestational trophoblastic neoplasia (GTN) is a group of interrelated lesions that results from abnormal proliferation of placental trophoblastic cells. Early diagnosis and treatment of GTN results in successful outcomes with fertility preservation.This study was intended to stratify GTN cases using WHO scoring system, to diagnose and manage cases as per protocol and to identify complications of treatment of GTN.

Methodology: This was a single center prospective observational study conducted at Medical college Kolkata from June 2017 to December 2018. All the diagnosed cases of GTN fulfilling the inclusion criteria were incorporated in the study, data were collected from history, clinical examination and investigations. All the data were tabulated and analyzed by standard statistical methods

Results:  In this study,  primiparous are more prone to have GTN and  molar pregnancy was the commonest antecedent event (71.4% of cases). 74.3% (26 out of 35) patients developed disease within four months of previous pregnancy. Anemia and vaginal bleeding were the presenting symptoms in >48.0% cases whereas hemoperitoneum,seizure, hemoptysis and respiratory distress were the rare presenting symptoms.In this study, the cases were diagnosed by histopathology or serial estimation of serum β-hcg. In our study, 91.4% patients  were successfully treated with methotrexate and only three cases received EMACO.

Conclusion: To conclude this study established that cases of GTN can be successfully treated by early diagnosis and timely management.
Study of Gastro-Oesophageal Reflux Disease among Patients with Type 2 Diabetes Mellitus presenting to Medicine Department at a Tertiary Care Hospital: A Descriptive Cross-sectional Study
Authors: Mahato Arun Kumar , Shah Madhu , Shrestha Nischal
Published: November 2022

Introduction: Gastro-oesophageal reflux disease is a chronic condition in which stomach contents regurgitates up into oesophagus causing symptoms like acidic taste in mouth, heart burn, bad breath and chronic cough. There is high prevalence of GERD in patients with Type 2 diabetes mellitus in the western countries, but such related data in our country are just few.

Objectives: To find out the prevalence of gastroesophageal reflux among patients with Type 2 Diabetes Mellitus attending Nobel Medical College Teaching Hospital.

Methodology: This was a descriptive cross-sectional study carried out in Department of Medicine of a tertiary care hospital from July 2020 to June 2021. Ethical approval was taken from Institutional Review Committee of Nobel Medical College Teaching Hospital (Reference number: 464/2020). Convenience sampling was done and data was collected from 191 patients presenting to the department. Collected data was entered, analysed in Statistical Package for the Social Sciences version 21 and documented for study. Point estimate at 95% Confidence Interval and descriptive statistics were interpreted as frequency, percentage, or as mean and standard deviations.

Results: Among 191 patients with type 2 diabetes, gastroesophageal reflux was seen in 78 (40.84%) (33.87-47.81 at 95% Confidence Interval) with more prevalent in male 42 (53.84%) than female 36 (46.15%). Mean duration of type 2 diabetes among reflux cases was 10.20± 5.40 years.

Conclusions: Gastroesophageal reflux was common associated condition among Diabetic patients.
Effect of Crop Establishment Methods on Performance of Rice in Rupandehi, Nepal
Authors: Poudel S. , Poudel B. , Acharya B. , Kathayat D. , Pant K. , Tamang K. R. , Timalsina N. , Ghimire P.
Published: November 2022

An on-station experiment was conducted to assess the growth, productivity and profitability of rice under various crop establishment methods at the agronomy farm of Paklihawa Campus, Rupandehi, Nepal in 2019. The experiment was laid out in Randomized Complete Block Design with five treatments and four replications. The treatments included: Traditional Transplanting–Random (TTR), Traditional Transplanting–Line (TTL), System of Rice Intensification (SRI), Wet Direct Seeded Rice-Line (WDSRL) and Wet Direct Seeded Rice-Broadcasting (WDSRB). The results showed that plant height, number of tillers at 40 DAT, number of grains per panicle, 1000 grain weight, grain yield, straw yield and grain sterility percentage were significantly influenced by crop establishment methods, whereas number of tillers at 60 DAP, number of effective tillers at harvest, panicle length and harvest index were not significantly different among the treatments. TTR method produced the highest grain yield (4.58 t/ha), straw yield (7.25 t/ha) and benefit-cost ratio (3.28) followed by TTL. Hence, traditional transplanting method of rice establishment was found better than WDSR and SRI in terms of productivity and profitability. Direct seeding and SRI could also be an attractive alternative to transplanting because of lower labor requirement and cost of production
Estudio de la urbanización de los distritos de Chorrillos, Miraflores y Barranco según la tradición «Los pacayares» de Ricardo Palma
Authors: Belladoni Portal Oriana Francesca
Published: November 2022

El presente artículo tiene como base la tradición «Los pacayares», de Ricardo Palma, en la que se describen las parcelas conocidas como pacayares, que, tras el pasar de los años, se convirtieron en quintas o casas de campo, y luego en casas modernas que forman parte de las urbanizaciones. Para nuestro estudio, tendremos en cuenta los distritos de Chorrillos, Miraflores y Barranco. Nos interesa abordar la evolución y el uso de los espacios desde mediados del siglo XIX hasta la actualidad; sobre todo, queremos hacer hincapié en el proceso de urbanización formal e informal y una apreciación de la variación de los elementos estructurales. Asimismo, se realizará una evaluación de la armonía entre las zonas destinadas al desarrollo humano y las zonas verdes.
A FEATURE FILM IN A RUSSIAN LANGUAGE CLASS WITH FOREIGN CADETS (ON THE EXAMPLE OF THE FILM "ONLY "OLD MEN" GO INTO BATTLE")
Authors: Gladkikh Irina Artemevna , Parfionova Tatiana Aleksandrovna
Published: November 2022

The article is devoted to the use of feature films in the course of Russian as a foreign language in a military university. Using films in Russian as a foreign language course allows cadets to improve their skills in all types of speech activity, contributes to the formation of their cultural competence, as well as increase interest and motivation to study Russian language. The work with the film is considered on the example of the movie "Only "old men" go into battle".
Physical activity of the elderly
Authors: Belitskii Kirill Andreevich
Published: November 2022

In this article, we will look at how physical activity is useful for older people, how it helps older people stay in shape
Principal Leadership in Developing the Competence of Islamic Religious Education Teachers
Authors: Illah Attok , Mansur Rosichin , Hidayatullah Muhammad Fahmi , Sariman Sariman , Seena Isamaae
Published: November 2022

This article aims to describe and analyze the leadership of the head of Madrasah Tsanawiyah Al-Ikhlas Bontang in improving the professionalism of Islamic religious education teachers. It uses a descriptive qualitative approach, and data collection techniques are conducted with in-depth interviews, participatory observation, and documentation. The results showed that planning is carried out by collecting ideas through the initial meeting of the year, forming a curriculum development team, obtaining curriculum documents, and determining an assessment program as the basis for implementing evaluations. Furthermore, management implementation through tahfidz learning in local content should be performed every morning for all students with a predetermined schedule. Evaluation through the memorization system positively impacts teachers to form a learning community, and the results of the tahfidz assessment are combined with all groups of Islamic religious subjects.
Periprocedural cerebrovascular complications and 30-day outcomes of endovascular treatment for intracranial vertebral artery dissecting aneurysms
Authors: Han Jiangli , Liu Fei , Chen Jigang , Tong Xin , Han Mingyang , Peng Fei , Niu Hao , Liu Lang , Liu Aihua
Published: November 2022

OBJECTIVE

The authors undertook an evaluation of periprocedural cerebrovascular complications and 30-day outcomes of endovascular treatment for intracranial vertebral artery dissecting aneurysms (IVADAs) and assessed the relevant risk factors.

METHODS

The authors included a series of 195 patients who had undergone endovascular treatment for 198 IVADAs. Clinical data, morphological characteristics, treatment details, and periprocedural cerebrovascular complications including intraprocedural rupture, intraprocedural thrombosis, intracranial hemorrhage (ICH), transient ischemic attack (TIA), and ischemic stroke (IS) were recorded. After evaluation of the 30-day modified Rankin Scale (mRS) scores, the authors applied univariate and multivariate logistic regression analyses to identify the risk factors for complications and 30-day unfavorable clinical outcomes.

RESULTS

There were no intraprocedural ruptures, but the authors recorded intraprocedural thrombosis (n = 5), ICH (n = 3), TIA (n = 1), and IS (n = 13), comprising an 11.1% (22/198) complication rate. Multivariate logistic regression analysis indicated that hyperlipidemia (odds ratio [OR] 3.17, 95% confidence interval [CI] 1.20–8.41, p = 0.020), IS history (OR 5.55, 95% CI 1.46–21.01, p = 0.012), and subarachnoid hemorrhage (SAH) (OR 4.48, 95% CI 1.52–13.20, p = 0.007) were risk factors for overall complications, whereas aneurysmal height (OR 0.77, 95% CI 0.61–0.98, p = 0.032) was a protective factor. SAH (OR 6.44, 95% CI 1.54–26.89, p = 0.011) and preprocedural mRS score > 2 (OR 5.07, 95% CI 1.01–25.59, p = 0.049) were independent risk factors for perforator occlusion stroke. Periprocedural cerebrovascular complications (OR 32.09, 95% CI 3.00–343.94, p = 0.004) and preprocedural mRS score > 2 (OR 319.92, 95% CI 30.28–3379.98, p < 0.001) were independent risk factors for 30-day unfavorable clinical outcomes.

CONCLUSIONS

Hyperlipidemia, IS history, and SAH were independent predictors for overall periprocedural cerebrovascular complications of endovascular treatment for IVADAs, but aneurysmal height was an independent protective factor. SAH and preprocedural mRS score > 2 were independent risk factors for perforator occlusion stroke. Preprocedural mRS score > 2 and periprocedural complications were independent risk factors for 30-day unfavorable clinical outcomes.
Clinical outcomes of non–small cell lung cancer brain metastases treated with stereotactic radiosurgery and immune checkpoint inhibitors, EGFR tyrosine kinase inhibitors, chemotherapy and immune checkpoint inhibitors, or chemotherapy alone
Authors: Dohm Ammoren E. , Tang Joseph D. , Mills Matthew N. , Liveringhouse Casey L. , Sandoval Maria L. , Perez Bradford A. , Robinson Timothy J. , Creelan Benjamin C. , Gray Jhanelle E. , Etame Arnold B. , Vogelbaum Michael A. , Forsyth Peter , Yu Hsiang-Hsuan Michael , Oliver Daniel E. , Ahmed Kamran A.
Published: November 2022

OBJECTIVE

Immune checkpoint inhibitors (ICIs) and epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR-TKIs) are commonly used in the systemic management of non–small cell lung cancer (NSCLC) brain metastases (BMs). However, optimizing control of NSCLC BM with stereotactic radiosurgery (SRS) and various systemic therapies remains an area of investigation.

METHODS

Between 2016 and 2019, the authors identified 171 NSCLC BM patients with 646 BMs treated with single-fraction SRS within 3 months of receiving treatment with ICIs (n = 56; 33%), EGFR-TKI (n = 30; 18%), chemotherapy and ICIs (n = 23; 14%), or standard chemotherapy alone (n = 62; 36%). Time-to-event analysis was conducted, and outcomes included distant intracranial control (DIC), local control (LC), and overall survival from SRS.

RESULTS

The median follow-up from BM diagnosis was 8.9 months (range 0.3–127 months). The 12-month Kaplan-Meier DIC rates were 37%, 53%, 41%, and 21% (p = 0.047) for the ICI, EGFR-TKI, ICI and chemotherapy, and chemotherapy-alone groups, respectively. On multivariate analysis, DIC was improved with EGFR-TKI (HR 0.4, 95% CI 0.3–0.8, p = 0.005) compared with conventional chemotherapy and treatment with SRS before systemic therapy (HR 0.5, 95% CI 0.3–0.9, p = 0.03) compared with after; and LC was improved with SRS before (HR 0.4, 95% CI 0.2–0.9, p = 0.03) or concurrently (HR 0.3, 95% CI 0.1–0.6, p = 0.003) compared with after. No differences in radionecrosis were noted by timing or type of systemic therapy.

CONCLUSIONS

The authors’ analysis showed significant differences in DIC based on receipt of systemic therapy and treatment with SRS before systemic therapy improved DIC. Prospective evaluation of the potential synergism between systemic therapy and SRS in NSCLC BM management is warranted.
Intranasal delivery of nanoliposomal SN-38 for treatment of diffuse midline glioma
Authors: Sasaki Takahiro , Watanabe Jun , He Xingyao , Katagi Hiroaki , Suri Amreena , Ishi Yukitomo , Abe Kouki , Natsumeda Manabu , Frey William H. , Zhang Peng , Hashizume Rintaro
Published: November 2022

OBJECTIVE

Diffuse midline gliomas, including diffuse intrinsic pontine gliomas (DIPGs), are among the most malignant and devastating childhood brain cancers. Despite aggressive treatment, nearly all children with these tumors succumb to their disease within 2 years of diagnosis. Due to the anatomical location of the tumors within the pons, surgery is not a treatment option, and distribution of most systematically administered drugs is limited by the blood-brain barrier (BBB). New drug delivery systems that bypass the BBB are desperately needed to improve outcomes of DIPG patients. Intranasal delivery (IND) is a practical and noninvasive drug delivery system that bypasses the BBB and delivers the drugs to the brain through the olfactory and trigeminal neural pathways. In this study, the authors evaluated the efficacy of nanoliposomal (LS) irinotecan (CPT-11) and an active metabolite of CPT-11, 7-ethyl-10-hydroxycamptothecin (SN-38), using IND in DIPG patient-derived xenograft models.

METHODS

In vitro responses to LS-CPT-11 and LS-SN-38 in DIPG cells were evaluated with cell viability, colony formation, and apoptosis assays. The cellular uptakes of rhodamine-PE (Rhod)–labeled LS-CPT-11 and LS-SN-38 were analyzed with fluorescence microscopy. Mice bearing DIPG patient-derived xenografts were treated with IND of LS-control (empty liposome), LS-CPT-11, or LS-SN-38 by IND for 4 weeks. In vivo responses were measured for tumor growth by serial bioluminescence imaging and animal subject survival. The concentration of SN-38 in the brainstem tumor administered by IND was determined by liquid chromatography–mass spectrometry (LC-MS). Immunohistochemical analyses of the proliferative and apoptotic responses of in vivo tumor cells were performed with Ki-67 and TUNEL staining.

RESULTS

LS-SN-38 inhibited DIPG cell growth and colony formation and increased apoptosis, outperforming LS-CPT-11. Rhod-labeled LS-SN-38 showed intracellular fluorescence signals beginning at 30 minutes and peaking at 24 hours following treatment. LC-MS analysis revealed an SN-38 concentration in the brainstem tumor of 0.66 ± 0.25 ng/ml (5.43% ± 0.31% of serum concentration). IND of LS-SN-38 delayed tumor growth and significantly prolonged animal survival compared with IND of LS-control (p < 0.0001) and LS-CPT-11 (p = 0.003). IND of LS-SN-38 increased the number of TUNEL-positive cells and decreased the Ki-67–positive cells in the brainstem tumor.

CONCLUSIONS

This study demonstrates that IND of LS-SN-38 bypasses the BBB and enables efficient and noninvasive drug delivery to the brainstem tumor, providing a promising therapeutic approach for treating DIPG.
Indications and outcomes of endoscopic transorbital surgery for trigeminal schwannoma based on tumor classification: a multicenter study with 50 cases
Authors: Kong Doo-Sik , Kim Yong Hwy , Lee Won-Jae , Kim Young-Hoon , Hong Chang-Ki
Published: November 2022

OBJECTIVE

Trigeminal schwannoma is a rare CNS tumor and involves the multicompartmental skull base. Recently, the endoscopic transorbital approach (ETOA) has emerged as a technique for minimally invasive surgery. The objective of this study was to evaluate the optimal indications and clinical outcomes of the ETOA for trigeminal schwannomas based on their tumor classification.

METHODS

Between September 2016 and February 2022, the ETOA was performed in 50 patients with trigeminal schwannoma at four tertiary hospitals. There were 15 men and 35 women in the study, with a mean age of 46.9 years. All tumors were classified as type A (predominantly involving the middle cranial fossa), type B (predominantly involving the posterior cranial fossa), type C (dumbbell-shaped tumors involving the middle and posterior fossa), or type D (involvement of the extracranial compartment). Type D tumors were also subclassified by ophthalmic division (D1), maxillary division (D2), and mandibular division (D3). Clinical outcome was analyzed, including extent of resection and surgical morbidities.

RESULTS

In this study, overall gross-total resection (GTR) was performed in 35 (70.0%) of 50 patients and near-total resection (NTR) in 9 patients (18.0%). The mean follow-up period was 21.9 (range 1–61.7) months. There was no tumor regrowth or recurrence during the follow-up period. Based on the classification, there were 17 type A tumors, 20 type C, and 13 type D. There were no type B tumors. Of the 13 type D tumors, 7 were D1, 1 D2, and 5 D3. For type A tumors, GTR or NTR was achieved using an ETOA in 16 (94.1%) of 17 patients. Eighteen (90.0%) of 20 patients with type C tumors attained GTR or NTR. Ten (76.9%) of 13 patients with type D tumors underwent GTR. Statistical analysis showed that there was no significant difference in the extent of resection among the tumor subtypes. Surgical complications included transient partial ptosis (n = 4), permanent ptosis (n = 1), transient diplopia (n = 7), permanent diplopia (n = 1), corneal keratopathy (n = 7), difficulties in mastication (n = 5), and neuralgic pain or paresthesia (n = 14). There were no postoperative CSF leaks or enophthalmos during follow-up.

CONCLUSIONS

This study showed that trigeminal schwannomas can be effectively treated with a minimally invasive ETOA in all tumor types, except those predominantly involving the posterior fossa (type B). For the extracranial compartments, D2 or D3 tumor types often require an ETOA combined with the endoscopic endonasal approach, while D1 tumor types can be treated using an ETOA alone.
ANALISIS KONSEP-KONSEP FISIKA BERBASIS KEARIFAN LOKAL PADA JAJANAN TRADISIONAL DAWET DAN KLEPON
Authors: Elisa Eti , Prabandi Audri Mely , Istighfarini Elma Tri , Alivia Haniyah , Inayah H. Latifa Widi , Nuraini Lailatul
Published: November 2022

ABSTRAKKearifan  lokal  adalah  identitas atau sebuah bentuk dari pengetahuan, wawasan, pemahaman maupun keyakinan serta adat yang dimiliki sebuah bangsa yang memiliki fungsi sebagai penutun manusia dalam berperilaku, mengelola kebudayaan dalam kehidupan di dalam komunitas ekologis. Kearifan lokal yang dekat dengan kehidupan masyarakat diharapkan dapat menjadi sumber belajar bagi siswa termasuk dalam proses pembelajaran fisika. Salah satu bentuk  kearifan lokal yaitu adanya jajanan tradisional. Dawet dan Klepon merupakan salah satu jajanan tradisional yang sudah lama dikenal masyarakat secara turun menurun. Penelitian ini bertujuan untuk menganalisis konsep fisika yang ada pada jajanan tradisional yaitu dawet dan klepon. Penelitian ini merupakan penelitian kualitatif. Teknik pengumpulan data menggunakan observasi, wawancara dan dokumentasi. Data dianalisis secara deskriptif. Hasil penelitian ini diperoleh dari proses pengolahan Dawet dan Klepon dengan mengidentifikasi konsep–konsep fisika terutama pada konsep tekanan, suhu dan kalor, koagulasi, dan hukum Archimedes. Dengan demikian, analisis konsep fisika pada pembuatan jajanan tradisional dapat dijadikan alternatif sumber belajar yang menarik bagi siswa. Kata kunci: kearifan lokal; konsep fisika; kalor; tekanan; koagulasi ABSTRACTLocal wisdom is an identity or a form of knowledge, insight, understanding as well as beliefs and customs of a nation that has a function as a human guide in behavior, managing culture in life in an ecological community. Learning about local wisdom will help physics learning in understanding its application in everyday life. Dawet and Klepon are traditional snacks that have long been known to the Javanese for generations. This study aims to analyze the physical concepts that exist in traditional snacks, namely dawet and klepon. This research is a phenomenological qualitative research, where this research uses triangulation techniques, namely by using observations and interviews accompanied by documentation. The results of this study were obtained from the processing of Dawet and Klepon by identifying the concepts of physics, especially on pressure, temperature and heat, coagulation, precipitation and Archimides' Law. keywords: local culture; physics concepts; heat; pressure; coagulation
VALIDITAS MODUL BERBASIS PROBLEM BASED LEARNING UNTUK MENINGKATKAN PENGUASAAN KONSEP PADA MATERI GETARAN HARMONIS
Authors: Ulfani Elza , Susilawati Susilawati , Gunada I Wayan
Published: November 2022

ABSTRAKPenelitian ini bertujuan untuk menghasilkan produk berupa modul fisika berbasis problem based learning yang valid untuk meningkatkan penguasaan konsep peserta didik pada materi getaran harmonis. Penelitian ini merupakan  jenis penelitian pengembangan atau Research and Development (R&D) dengan menggunakan model ADDIE yang terdiri dari tahap Analysis, Design, Development, Implementation, dan Evaluation. Modul ini dikembangkan untuk materi getaran harmonis. Pada artikel ini hanya dilakukan sampai pada tahap development. Instrumen penelitian yang digunakan adalah lembar validasi. Teknik pengumpulan data menggunakan lembar validasi yang diisi oleh 3 validator ahli dan 3 validator praktisi menggunakan skala Likert. Komponen modul yang dinilai terdiri dari indikator isi, kebahasaan, penyajian dan kegrafisan. Peningkatan penguasaan konsep diukur berdasarkan indikator, mengingat (C1), memahami (C2), mengaplikasikan (C3), menganalisis (C4), mengevaluasi (C5) dan mencipta (C6). Berdasarkan analisis hasil validasi oleh validator ahli dan validator praktisi diperoleh nilai rata-rata persentase kevalidan sebesar 81,07% dengan kategori sangat valid dan penguasaan konsep mengalami peningkatan sebesar 0,67 dan dikategorikan sedang. Dengan demikian, dapat disimpulkan bahwa modul fisika berbasis problem based learning sangat valid digunakan dalam pembelajaran. Kata kunci: validitas; modul fisika; problem based learning; penguasaan konsep ABSTRACTThis study aims to produce a product in the form of a valid problem-based learning physics module to improve students' conceptual mastery of harmonic vibration material. This research is a type of research development or Research and Development (R&D) using the ADDIE model which consists of the Analysis, Design, Development, Implementation, and Evaluation stages. This module is developed for harmonic vibration material. This article is only carried out until the development stage. The research instrument used was a validation sheet. The data collection technique used a validation sheet filled out by 3 expert validators and 3 practitioner validators using a Likert scale. The module components assessed consist of indicators of content, language, presentation, and graphics. The concept mastery indicators consist of remembering (C1), understanding (C2), applying (C3), analyzing (C4), evaluating (C5), and creating (C6). Based on the analysis of the validation results by expert validators and practitioner validators, the average value of the percentage of validity is 81.07% with a very valid category. Thus, it can be concluded that the physics module based on problem-based learning is very valid to be used in learning. Keywords: validity; physics module; problem-based learning; mastery of concepts.
STRATEGI PEMASARAN LEMBAGA PENDIDIKAN DI SEKOLAH DASAR DHARMA MULIA DUSUN BANARAN GETASAN
Authors: Lisnawati Aat , iga luhsasi Dwi , Sadjiarto Arief
Published: November 2022

SD Dharma Mulia merupakan sekolah dengan latar belakang Budha, sekolah yang berada di bawah naungan yayasan Budha ini mengalami penurunan jumlah siswanya selama dua tahun karena faktor kepercayaan orang tua dan tidak ada bukti kelulusan. Penelitian ini bertujuan untuk mengetahui Strategi Pemasaran Lembaga Pendidikan di Sekolah Dasar Dharma Mulia di Dusun Banaran Getasan. Model penelitian adalah pendekatan kualitatif dengan teknik pengumpulan data yaitu wawancara, observasi dan dokumentasi. Hasil penelitian strategis yang dilakukan oleh SD Dharma Mulia yaitu dengan menerapkan pemasaran internal, pemasaran eksternal dan pemasaran interaktif. Alat yang digunakan dalam melakukan strategi pemasaran adalah dengan menerapkan bauran pemasaran yang terdiri dari 7P (Produk, Harga, Tempat, Promosi, Orang, Bukti fisik, proses). Kegiatan pemasaran yang dilakukan di SD Dharma Mulia adalah dengan membuat brosur dan spanduk serta dilakukan melalui media sosial seperti, Facebook, Instagram dan Whatsapp
Wilhelm II and the resignation of Otto von Bismarck
Authors: Matveeva Anna
Published: November 2022

The article focuses on the turning point in the history of the German Empire in 1871–1918, associated with the circumstances of the resignation of the first Imperial Chancellor and Minister-President of Prussia Otto von Bismarck in March 1890 and the transition to the so-called Wilhelmian period in the history of the country. The subject has been well studied in German historiography, yet it is still a matter for discussion among historians. Drawing on studies already undertaken, the author supplements them with information from the correspondence between the Russian Embassy in Berlin and the Ministry of Foreign Affairs of the Russian Empire in January–April 1890, which is largely unknown to the general public. The author focuses on the character and personality of Emperor Wilhelm II, the principal stages in his biography up to 1890 which influenced the emergence and course of the resignation crisis; the political differences between the Emperor and the Chancellor which became the catalyst for their break-up; the consequences of Bismarck's resignation and the impact of these events on the subsequent development of Germany. As a result of this research, the author concludes that, firstly, the main reason was psychology, the psychological disposition of the monarch. By firing the chancellor, he wanted to get a sense of freedom. A man who had been emotionally very dependent on his 'mentors' his whole life was trying to break free from the tutelage of the chief of them, Bismarck. Secondly, the German Empire was in no way inferior to the British Empire, whose reigning house he had a whole gamut of love-hate feelings towards. In such a situation, Bismarck, who had resisted state colonial policy and domestic transformation in every way, was not at all suited to be the main pillar of the new monarch, who had such far-reaching, albeit very vague, plans. His notion of the ability to single-handedly determine the entire policy of a country such as Germany at the end of the nineteenth century was inherently doomed to failure. Removing a constraining and guiding factor such as Bismarck from the system made it even more unstable. But there was no other way out of the conflict, the Bismarcks could not in any circumstances replace the Hohenzollerns.
Patriarch of Russian Diplomacy Yegor Yegorovich Staal (1822–1907)
Authors: Rybachenok Irina
Published: November 2022

One of the oldest Russian diplomats, Yegor Yegorovich Staal, spent a significant part of his career as Ambassador Extraordinary and Plenipotentiary to the Queen of Great Britain and Ireland, the Empress of India. He made a significant contribution to the stabilization of Russian-English relations. It was a period of acute conflicts and crises in the international arena in the mid-80s – late 90s of the XIX century. No special studies on Staal have yet been published. The limited scope of the article does not allow us to present a complete picture of his activities in the diplomatic field. The author of the article saw her task in highlighting the main milestones of the diplomat's life and views, professional techniques and methods that he used during the negotiations on the Afghan border in 1884–1885 and as the head of the Russian delegation at the First Peace Conference in 1899 in the Hague. The source base of the study was the publication of diplomatic documents unpublished reports of Staal to the Ministry of Foreign Affairs, materials of his personal archive preserved in the State Archive of the Russian Federation, as well as his letters deposited in the GA of the Russian Federation. The awards received by Staal in his native fatherland and those states where he represented the interests of Russia indicate a high appreciation of his fruitful works.
GENERATING FUNCTION FOR SCHUR POLYNOMIALS
Authors: Bedratyuk L.
Published: November 2022

For the generating function $$
G_n(\mathbi{x},\mathbi{t})=\sum_{\lambda} \mathbi{s}_{\lambda}(x_1,x_2,\ldots, x_n) t_1^{\lambda_1 } t_2^{\lambda_2 } \cdots t_n^{\lambda_n},
$$ where the Sсhur polynomials $\mathbi{s}_{\lambda}(x_1,x_2,\ldots, x_n) $ are indexed by partitions $ \lambda $ of length no more than $ n $ the explicit form for $ n = 2,3 $ is calculated and a recurrent relation for an arbitrary $ n $ is found. It is proved that $ G_n (\mathbi {x}, \mathbi {t}) $ is a rational function
$$G_n(\boldsymbol{x}, \boldsymbol{t})=\frac{P(\boldsymbol{x}, \boldsymbol{t})}{Q(\boldsymbol{x}, \boldsymbol{t})},$$
the numerator and denominator of which belong to the kernel of the differential operator
$$
\mathcal{D}_n=\sum_{i=1}^n x_i \frac{\partial}{\partial x_i}- \sum_{i=1}^n t_i \frac{\partial}{\partial t_i}.
$$
For the numerator $ P (\boldsymbol {x}, \boldsymbol {t}) $ we find its specialization at $ t_1 = t_2 = \cdots = t_n = 1. $
PENGARUH MEDIA PEMBELAJARAN PAPAN PINTAR (SMART BOARD) TERHADAP KEMAMPUAN MEMBACA PERMULAAN PESERTA DIDIK PADA MATA PELAJARAN BAHASA INDONESIA KELAS 1 SEKOLAH DASAR
Authors: Putri Rosalina , Kasriman
Published: November 2022

Penelitian ini dilatar belakangi oleh rendahnya kemampuan membaca permulaan siswa kelas 1 di SDN Pulau Harapan 01 Pagi. Penelitian ini bertujuan untuk mengetahui pengaruh media pembelajaran papan pintar (smart board) terhadap kemampuan membaca permulaan peserta didik pada mata pelajaran bahasa indonesia kelas 1 SDN pulau harapan 01 pagi semester 2 tahun ajaran 2021/2022. Metode penelitian yang digunakan adalah metode penelitian kuantitatif dengan desain penelitian quasi eksperimen dengan jenis post-test only control group design. Teknik pengambilan sampel yang digunakan adalah sampel jenuh. Alat pengumpul data menggunakan tes kemampuan membaca permulaan. Analisis data yang digunakan yaitu uji beda dan effect size. Hasil penelitian ini diperoleh data sebagai berikut Uji hipotesis menggunakan rumus uji t-test diperoleh thitung > ttabel yaitu 3,228 > 2,002. Dengan demikian H0 di tolak dan H1 diterima, yang berarti bahwa terdapat pengaruh media pembelajaran papan pintar (smart board) terhadap kemampuan membaca permulaan peserta didik pada mata pelajaran bahasa indonesia kelas 1 SDN pulau harapan 01 pagi. Uji effect size mendapatkan hasil 0,986 yang berarti berpengaruh sangat tinggi. Dengan demikian, dapat disimpulkan bahwa papan pintar berpengaruh signifikan terhadap kemampuan membaca permulaan.
PENGARUH PENGGUNAAN MEDIA INTERAKTIF BERBASIS WORDWALL QUIZ TERHADAP HASIL BELAJAR IPA DI SEKOLAH DASAR
Authors: Khofifah Indra Sukma  , Trisni Handayani
Published: November 2022

Hasil belajar yang rendah merupakan suatu masalah dalam proses pembelajaran. Rendahnya hasil belajar dapat disebabkan karena adanya beberapa faktor yang mempengaruhi selama proses pembelajaran berlangsung, salah satunya adalah kurangnya inovasi dalam pemilihan media pembelajaran. Hal tersebut dapat menyebabkan pembelajaran menjadi kurang menarik dan membosankan sehingga berakibat pada kurangnya motivasi peserta didik dalam mengikuti proses pembelajaran, yang berdampak pada penurunan hasil belajar. Oleh karena itu, peneliti tertarik melakukan penelitian menggunakan media interaktif berbasis wordwall quiz untuk meningkatkan hasil belajar peserta didik pada mata pelajaran IPA. Tujuan penelitian ini adalah untuk mengetahui pengaruh penggunaan media interaktif berbasis wordwall quiz terhadap hasil belajar IPA kelas IV SDN pasir putih 03. Metode penelitian yang digunakan adalah penelitian kuantitatif eksperimen dengan desain quasi experimental design tipe Post-test only control group design. Populasi dalam penelitian ini yaitu seluruh peserta didik kelas IV SDN Pasir Putih 03. Teknik pengambilan sampel dalam penelitian ini adalah sampling jenuh dengan jumlah sampel 35 peserta didik sebagai kelas eksperimen dan 34 peserta didik sebagai kelas kontrol. Teknik pengumpulan data berupa Post -test menggunakan soal tes dalam bentuk pilihan ganda. Hasil penelitian menunjukan bahwa penggunaan media interaktif berbasis wordwall quiz memberikan dampak yang positif bagi hasil belajar peserta didik. Hasil belajar IPA peserta didik yang menggunakan media interaktif berbasis wordwall quiz lebih unggul dibandingkan dengan pembelajaran konvensional atau tanpa melibatkan media didalamnya. Dengan demikian, dapat disimpulkan bahwa penggunaan media interaktif berbasis wordwall quiz berpengaruh terhadap hasil belajar IPA kelas IV SDN pasir putih 03.
PENGARUH SELF EFFICACY TERHADAP MINAT SISWA SEKOLAH DASAR MENGGUNAKAN APLIKASI GOOGLE CLASSROOM BERDASARKAN MODEL TAM
Authors: Muhammad Arfi Rizki Nanda  , Zulherman
Published: November 2022

Masalah pada penelitian ini yaitu minimnya penggunaan media pembelajaran yang menarik dan kreatif guna memudahkan peserta didik agar dapat mengerti materi yang dipelajari pada mata pelajaran matematika. Tujuan dari penelitian ini adalah untuk mengetahui apakah terdapat pengaruh Self Efficacy terhadap minat peserta didik sekolah dasar menggunakan Google classroom berdasarkan model TAM. Google classroom memudahkan peserta didik dan guru agar tetap terhubung, baik di dalam maupun di luar kelas dalam pembelajaran online. Penelitian ini menggunakan metode penelitian kuantitatif eksperimen dengan desain survey. Pengumpulan data pada penelitian ini melalui observasi dengan memberikan perlakuan aplikasi Google classroom, kemudian menyebarkan kuesioner kepada kelas IV dengan jumlah 90 peserta didik. Pada penelitian ini terdapat 3 variabel yang valid dan 2 variabel yang tidak valid, untuk menganalisis data yang telah dihasilkan menggunakan SmartPLS. Dan hasil yang didapat bahwa adanya pengaruh Self Efficacy terhadap minat peserta didik dengan menggunakan Google classroom di masa pandemi sebagai platform pembelajaran online.
PENGARUH MEDIA POWER POINT INTERAKTIF BERBASIS APLIKASI GOOGLE CLASSROOM TERHADAP HASIL BELAJAR IPA DI SEKOLAH DASAR
Authors: Farah Putri Salsabila  , Khavisa Pranata
Published: November 2022

Semenjak masa pandemi Covid-19, aktivitas belajar mengajar secara daring membuat hasil belajar peserta didik menurun. Sehingga para guru banyak yang mengubah dan mulai berinovasi mencari media pembelajaran yang tepat dan cocok untuk diterapkan didalam sistem belajar mengajar dengan menyesuaikan keadaan saat ini. Tujuan penelitian ini yakni guna mengetahui adanya pengaruh dari media pembelajaran Power Point Interaktif berbasis aplikasi Google Classroom terhadap hasil belajar IPA peserta didik kelas V di SDN Bambu Apus 04. Pada penelitian ini menerapkan metode kuantitatif dengan jenis penelitian True Eksperimen (Eksperimen Murni) untuk menentukan sampel secara random dengan menggunakan teknik Prettest-Posttest Control Group Design memanfaatkan dua sampel kelas untuk penelitian yaitu kelas eksperimen dan kelas control sebagai pembanding. Populasi pada penelitian ini yakni peserta didik kelas V SDN Bambu Apus 04 dengan jumlah sampel 32 peserta didik di kelas eksperimen serta 32 peserta didik di kelas kontrol. Instrumen yang digunakan berupa soal evaluasi untuk mengukur dan melihat hasil belajar peserta didik yang memakai media pembelajaran Power Point Interaktif berbasis aplikasi Google Classroom, kemudian diukur dengan menggunakan uji normalitas data, uji homogenitas data, uji independent sampel t test. Penelitian ini membuktikan adanya keberhasilan penggunaan media pembelajaran Power Point Interaktif berbasis aplikasi Google Classroom terhadap hasil belajar IPA peserta didik kelas V.