bluuebunny/crossref_metadata_2025 huggingface dataset:
Heritage Science Contribution to the Understanding of Meaningful Khipu Colours
Authors: Milillo Lucrezia , Hacke Marei , Norrehed Sara , Degano Ilaria , Gherardi Francesca , Gunnarsson Ellinor
Published: February 2023

This work is the first scientific study of khipu dyes and inorganic mordants and auxiliaries, paving the way for a new approach to understanding khipus’ meaningful materiality, technology, and colours. Khipus have usually been described as “Andean knotted records”, but they are much more than complex knotted cords: a great part of the information encoded resides in khipus’ incredible colours. The objects of this study are two Wari khipus, 1932.08.0001 and 1932.08.0002, now at the Museum of World Culture in Gothenburg, Sweden. After a morphological study of the khipus, the objects were imaged with multiband imaging (MBI) as an aid for the sampling decisional process. The khipus were then analysed non-invasively by X-ray fluorescence (XRF) spectroscopy on selected areas of particular interest. The khipus were consequently sampled for elemental characterisation by micro-XRF, and liquid chromatography coupled with high-resolution mass spectrometry (HPLC–HRMS) for characterising the organic dye composition. This paper presents a part of the results of the project “Meaningful materials in the khipu code”, with the intent to shed light on the difficulties and possibilities of investigating khipu colours and dyestuffs. MBI and XRF revealed unforeseeable structural characteristics, such as remnants from a heavily degraded thread in an area of missing thread wrapping and a dual-coloured thread that was previously deemed single-coloured. The organic dyes identified by HPLC–HRMS comprised indigoids, cochineal, and an unknown flavonoid-based dyestuff. XRF of the inorganic components revealed associations of several elements with specific colours.
A Na+/H+ Antiporter Gene from Rosa multiflora (RmNHX2) Functions in Salt Tolerance via Modulating ROS Levels and Ion Homeostasis
Authors: Luo Haiyan , Shen Yuxiao , Chen Linmei , Cui Yongyi , Luo Ping
Published: February 2023

High salinity restricts plant growth and geographic distribution. Plant intracellular Na+/H+ (NHX) antiporters have critical roles in plant development and stress response. However, the molecular functions of RmNHXs in Rosa multiflora remain unclear. In this study, we identified 11 putative RmNHXs in R. multiflora according to the genome-wide analysis. The RmNHXs were classified into three classes. Most of the RmNHXs were responsive to salt stress, with the greatest upregulation being observed in RmNHX2. RmNHX2 was localized at the tonoplast. RmNHX2 overexpression resulted in the enhanced salt tolerance in tobacco, whereas virus-induced gene silencing (VIGS) of RmNHX2 in R. multiflora elevated salt susceptibility. Under salt treatment, the transgenic tobaccos achieved less reactive oxygen species (ROS) accumulation and higher activities of antioxidant enzymes, which complied with the upregulated expressions of antioxidant genes. Moreover, RmNHX2-overexpression lines had a lower level of Na+, a higher level of K+, and a lower Na/K ratio. In contrast to the mentioned, VIGS of RmNHX2 in R. multiflora exhibited the opposite phenotype, accompanied by a compromised salt tolerance. Regarded together, these results demonstrate that RmNHX2 enhances plant salt tolerance by maintaining proper ion homeostasis, as well as by accelerating ROS scavenging.
Spinach Responds to Minimal Nutrient Supplementation in Aquaponics by Up-Regulating Light Use Efficiency, Photochemistry, and Carboxylation
Authors: Tsoumalakou Evangelia , Mente Eleni , Vlahos Nikolaos , Levizou Efi
Published: February 2023

Aquaponics is a promising cultivation technique for combined production of crops and fish, on the condition of tackling certain nutrients deficiencies. The aim of the present study was to examine the limitations imposed by the system on spinach (Spinacia oleracea) growth and functional performance and to identify the minimum nutrient supplementation for their optimization. Spinach was co-cultivated with red tilapia under three treatments; iron (Fe) and iron with potassium (Fe+K) enrichment was compared with the no-external input control. During a 45-day experiment, the photosynthetic performance, photosynthetic machinery efficiency, total chlorophylls content, and leaf reflectance were monitored, along with leaf nutritional state, antioxidant activity, and growth responses of fish and crops. Control plants showed symptoms of Fe deficiency, extensive chlorosis, stunted growth, and functional impairment already from day 10. The latter consisted of a coordinated down-regulation of photochemistry, carboxylation, and light-use efficiency. Fe-treated plants exhibited similar growth and functional performance with Fe+K-treated plants but outperformed them in chlorophyll content, photosynthetic rates, and photochemical efficiency, mainly due to higher quantum yield of electron transport. Fish growth remained unaffected. Fe-deficiency was identified as the major bottleneck for spinach cultivation in closed-loop aquaponics, and our results demonstrate that only Fe supplementation may sufficiently improve spinach function and yield.
Changes in Cell Wall Sugar Neutral Composition Contribute to Apple Texture Loss during Storage among Cultivars
Authors: Liu Hui , Lin Shiyu , Zhang Mengyuan , Lv Yanrong , Ma Yanping , Rao Jingping , Zhu Qinggang
Published: February 2023

Fruit texture affects apples’ quality, consumer preference, and shelf life. The cell wall neutral sugar composition was reported to contribute to apples’ mechanical properties at harvest. However, the contributions of cell wall neutral sugar composition to apple texture loss during storage among different cultivars are still unclear. In this study, six cultivars of the apple fruit were stored at 25 °C for 60 days (i.e., rapid loss of texture: ‘Jiguan’, ‘Yindu’, and ‘Qinguan’; slow loss of texture: ‘Fuji’, ‘Huaguan’, and ‘Cripps pink’). The texture properties, physiological indicators, and expression of cell wall-related genes were investigated every 20 d. The results showed that apple cultivars with rapid texture loss showed a faster loss in flesh hardness and crispness, and a higher level of flesh tightness and pericarp break distance, than the cultivars with slow texture loss. Galactose content showed the closest association with the texture properties among the cell wall neutral sugar compositions. The rapid loss of galacturonic acid content and the expression of MdPG1 were higher in the cultivars with rapid texture loss than in those with slow texture loss. These results indicated that changes in cell wall neutral sugar composition contribute to apple texture loss during storage among cultivars.
Recent Research Advances of Small Regulatory RNA in Fruit Crops
Authors: Zaman Fatima , Zhang Meng , Wu Rong , Zhang Qinglin , Luo Zhengrong , Yang Sichao
Published: February 2023

MicroRNAs (miRNAs) are endogenous noncoding small RNAs containing 21–24 nucleotides (nt) that regulate gene expression precisely and efficiently at the posttranscriptional level through the negative regulation of target messenger RNA (mRNA) expression, such as translational inhibition or degradation. Likewise, as a controlling element, miRNA itself is regulated by a variety of factors when performing its basic purposes, such as SNP detection, miRNA purging, methylation, and the circadian clock in model crops. In current years, miRNA-mediated controls have been intensely investigated in horticultural plants, leading to the discovery of numerous novel mechanisms that exhibit significantly greater mechanistic complexity and distinctive regulatory properties than those explored in model species. In fruit crops, miRNAs play a crucial role corresponding to various biological, metabolic functions and environmental challenges, including growth, expansion, response to biotic and abiotic stress, signaling of growth hormones, and the regulation of secondary product metabolism. In this study, we appraisal the current improvement of small regulatory RNA research in fruit crops, emphasizing miRNA mechanisms and their correlation with key trait rule. Considering that miRNAs engaged in the regulation of all aspects of fruit tree life activities, we focus here on their biosynthesis, target genes, function and regulatory network, as well as the mechanistic connection among them, to provide a theoretic base and breakthrough for upcoming exploration on miRNAs in fruit plants.
Traffic Noise at Moderate Levels Affects Cognitive Performance: Do Distance-Induced Temporal Changes Matter?
Authors: Müller Leon , Forssén Jens , Kropp Wolfgang
Published: February 2023

Urbanization leads to an increased demand for urban housing, which can be met by building dwellings closer to streets. Regulations often limit equivalent sound pressure levels which do not account for changes in time structure that occur when decreasing the road distance. This study investigates the effect of such temporal changes on subjective workload and cognitive performance. A group of 42 participants performed a continuous performance test as well as a NASA-TLX workload test under three different sound conditions, i.e., close traffic, far traffic, both with the same equivalent sound pressure level of LAeq≈40 dB, and silence. Additionally, participants answered a questionnaire regarding their preferred acoustic environment for concentrated working. Significant effects of the sound condition on the multivariate workload results as well as on the number of commission errors in the continuous performance test were found. Post hoc tests showed no significant differences between the two noise conditions, but there were significant differences between noise and silence. This indicates that moderate traffic noise levels can influence cognitive performance and perceived workload. If there is a difference in the human response to road traffic noise with constant LAeq but different time structures, the used methods are not suitable to detect them.
Latent Trajectories and Risk Factors of Prenatal Stress, Anxiety, and Depression in Southwestern China—A Longitudinal Study
Authors: Gao Yuwen , Tang Xian , Deng Ruibin , Liu Jiaxiu , Zhong Xiaoni
Published: February 2023

(1) Background: Few studies have explored the heterogeneity of trajectories of stress, anxiety, and depressive symptoms during pregnancy. This study aimed to explore the trajectory groups of stress, anxiety, and depressive symptoms in women during pregnancy and the risk factors associated with those groups. (2) Methods: Data came from pregnant women recruited from January to September 2018 in four hospitals in Chongqing Province, China. A structured questionnaire was given to pregnant women, which collected basic information, including personal, family, and social information. The growth mixture model was applied to identify potential trajectory groups, and multinomial logistic regression was applied to analyze factors of trajectory groups. (3) Results: We identified three stress trajectory groups, three anxiety trajectory groups, and four depression trajectory groups. Less developed regions, inadequate family care, and inadequate social support were associated with a high risk of stress; residence, use of potentially teratogenic drugs, owning pets, family care, and social support were strongly associated with the anxiety trajectory group; family care and social support were the most critical factors for the depression trajectory group. (4) Conclusions: The trajectories of prenatal stress, anxiety, and depressive symptoms are dynamic and heterogeneous. This study may provide some critical insights into the characteristics of women in the high-risk trajectory groups for early intervention to mitigate worsening symptoms.
Recent Advances in Thallium Removal from Water Environment by Metal Oxide Material
Authors: Ren Xiaoyi , Feng Haopeng , Zhao Mengyang , Zhou Xin , Zhu Xu , Ouyang Xilian , Tang Jing , Li Changwu , Wang Jiajia , Tang Wangwang , Tang Lin
Published: February 2023

Thallium is widely used in industrial and agricultural development. However, there is still a lack of systematic understanding of its environmental hazards and related treatment methods or technologies. Here, we critically assess the environmental behavior of thallium in aqueous systems. In addition, we first discuss the benefits and limitations of the synthetic methods of metal oxide materials that may affect the practicality and scalability of TI removal from water. We then assess the feasibility of different metal oxide materials for TI removal from water by estimating the material properties and contaminant removal mechanisms of four metal oxides (Mn, Fe, Al, and Ti). Next, we discuss the environmental factors that may inhibit the practicality and scalability of Tl removal from water. We conclude by highlighting the materials and processes that could serve as more sustainable alternatives to TI removal with further research and development.
Health Care Organization in Poland in Light of the Refugee Crisis Related to the Military Conflict in Ukraine
Authors: Prusaczyk Artur , Bogdan Magdalena , Vinker Shlomo , Gujski Mariusz , Żuk Paweł , Kowalska-Bobko Iwona , Karczmarz Sabina , Oberska Joanna , Lewtak Katarzyna
Published: February 2023

Background: Poland is witnessing a migration crisis caused by the ongoing military conflict in Ukraine. In addition to housing and necessities, 1.8 million Ukrainians that had taken refuge in Poland must have access to medical care. We aim to propose a strategy for implementing the changes in the Polish health care system in response to the Ukrainian refugee crisis. Methods: A literature review on organizational changes in the functioning of health care systems during the migration crises worldwide in recent years and brainstorming in order to develop a strategy for implementing changes in the Polish health care system in response to the Ukrainian refugee crisis. Results: The proposed strategy for implementing the changes in the Polish health care system is based on building health care resilience and adaptation to different crises. The operational objectives of organization-related activities are: (1) preparation of medical facilities to provide help for refugees, (2) development and implementation of the communication system, (3) implementation of available digital solutions, (4) organization of the diagnostic and medical services, (5) and implementation of changes in the management of medical facilities. Conclusions: Urgent reorganization is required to respond to an unavoidable increase in the demand for health care services.
Understanding and Balancing Generalist-Specialist Approaches in Dementia Research and Care Practice, Qualitative Research with 44 Dementia Professors in The Netherlands
Authors: Huijsman Robbert
Published: February 2023

Dementia is one of the leading causes of death and disability among citizens and a societal challenge because of aging worldwide. As dementia has physical, psychological, social, material, and economic impacts, both research and care practice require many disciplines to develop and implement diagnostics, medical and psychosocial interventions, and support, crossing all domains of housing, public services, care, and cure. Notwithstanding large research efforts, much knowledge about mechanisms, interventions, and needs’ based care pathways is still lacking. To cope with these challenges in research and practice, this paper is the first to question how generalist and specialist orientations can be unfolded. In the Netherlands, all dementia professors (N = 44) at eight Dutch academic centers have been interviewed. Qualitative analyses revealed three subgroups of dementia professors, one with a generalist orientation, one adhering to specialist approaches, and a third group that pleas for mixed orientations, with some differences between research and care practice. Each group has arguments for its generalist/specialist vision, but the synthesis suggests a paradigm of personalized and integrated dementia care, aimed at the individual in his own living environment. Sustainable strategies to cope with dementia require (inter)national programs and strong collaboration to build multi- and interdisciplinarity within and between research and practice.
The Hybrid Capture 2 Results in Correlation with the Pap Test, Sexual Behavior, and Characteristics of Romanian Women
Authors: Voidăzan Toader Septimiu , Uzun Cosmina Cristina , Kovacs Zsolt , Rosznayai Florin Francisc , Turdean Sabin Gligore , Budianu Mihaela-Alexandra
Published: February 2023

Background: Human papillomavirus (HPV) infection is the major cause of cervical cancer (CC); hence, it is critical to understand the processes by which HPV infection causes squamous intraepithelial lesions, as well as the proper diagnostic tools. The objective of this study was to establish the correlations between Pap test results and Hybrid Capture 2 (HC2) tests findings. Materials and methods: This study included 169 women between the ages of 30 and 64, who presented for consultation in gynecological clinics in both the public and the private sectors. These women reported symptoms, such as abnormal vaginal discharge and genital irritation, as well as early onset of sexual activity, multiple sexual partners, history of other sexually transmitted infections or high-risk sexual partners, immunosuppression, or tobacco smoking. Pap tests and HPV testing, using the HC2 method, were performed for the women enrolled in the study, including data gathered after patients completed questionnaires concerning their sexual behavior. Results: The HC2 method revealed that 66 patients (39.1%) tested positive for high-risk HPV types. Of the patients with positive results, 14 (21.2%) presented Atypical Squamous Cells of Undetermined Significance (ASC-US) compared to 10 (9.7%) patients in the negative group (p = 0.042). Atypical Squamous Cells for which a high-grade lesion cannot be excluded (ASC-H) were identified primarily in women with positive HC2 (6.1%). HR-HPV positivity was substantially more associated with low-grade ASC-US or low-grade squamous intraepithelial lesion (LSIL) and high-grade ASC-H cytology (OR = 2.53; 95% CI: 1.10–5.80, respectively, OR = 14.9; 95%CI: 1.006–34.59). Unmarried women (31.8%; p = 0.004) and women with multiple partners (over four partners, 10.6%; p = 0.03) were more likely to have an HPV infection when compared to married women and those with fewer sexual partners. Conclusions: Understanding the epidemiology of HPV genital infections is essential for developing preventive measures against this infection and CC. Identifying the most prevalent HPV types, and determining the incidence of HPV oncogenic infections, in conjunction with Pap test results and sexual behavior information, can constitute part of an algorithm for the efficient management of cervical intraepithelial lesions.
A Framework and System Design for Medicines Resources Allocation: A Multi-Stakeholder Assessment of Processes and Electronic Platform Needs
Authors: Alanazi Abdullah , Alshatri Ibtihal , Aldosari Bakheet
Published: February 2023

Utilizing resources effectively is becoming more critical, especially with the ever-increasing healthcare cost. Little is known about the current practices used by healthcare organizations for the procurement, allocation, and utilization of medical resources. Moreover, the available literature needed to be enriched to bridge the link between resource utilization and allocation processes’ performance and outcomes. This study investigated the processes that major healthcare facilities in Saudi Arabia apply to procure, allocate and utilize medicines resources. The work explored the role of electronic systems and provided a system design and conceptual framework to enhance the availability and utilization of resources. A three-part multi-method, multi-field (healthcare and operational), and multi-level exploratory and descriptive qualitative research design were used to collect the data that was analyzed and interrupted to feed the “future state” model. The findings demonstrated the current state procedure and discussed the challenges and the experts’ opinions on developing the framework. The framework includes various elements and perspectives and is designed based on the results of the first part and was further validated by experts who were optimistic about the inclusiveness of this framework. Some major technical, operational, and human factors were perceived as obstacles by the subjects. Decision-makers can adopt the conceptual framework to gain insights into interrelated objects, entities, and processes. The findings of this study can imply future directions for research and practices.
Quality and Microbiological Safety of Poultry Meat Marinated with the Use of Apple and Lemon Juice
Authors: Augustyńska-Prejsnar Anna , Kačániová Miroslava , Ormian Małgorzata , Topczewska Jadwiga , Sokołowicz Zofia
Published: February 2023

The aim of the study was to evaluate the use of apple juice for the marinating of poultry meat and its effect on the technological as well as sensory characteristics and microbiological safety of the raw product after heat treatment. Broiler chicken breast muscles were marinated for 12 h in apple juice (n = 30), a mixture of apple and lemon juice (n = 30) and compared with those in lemon juice (n = 30). The control group (n = 30) consisted of unmarinated breast muscles. Following the evaluation of the technological parameters (pH, L*, a*, b* colour, cutting force, cooking losses) quantitative and qualitative microbiological evaluations were performed on the raw and roasted products. The microbiological parameters were determined as total Mesophilic aerobic microorganisms, Enterobacteriaceae family, and Pseudomonas count. The bacterial identification was performed using a matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry. The marinating resulted in lower pH value, but increased tenderness of raw and roasted products. Marinating chicken meat in both apple and lemon juices, including their mixtures and in the control sample, resulted in increased yellow saturation (b*). The highest flavour desirability and overall desirability were obtained in products marinated using a mixture of apple and lemon juice, while the most desirable aroma was obtained from products marinated with apple juice. A significant antimicrobial effect was observed in marinated meat products compared to unmarinated, irrespective of the type of marinade used. The lowest microbial reduction was observed in the roasted products. Apple juice can be used as a meat marinade because it promotes interesting sensory properties and improves the microbiological stability of poultry meat while maintaining the product’s good technological characteristics. It makes a good combination with the addition of lemon juice.
Cost-Impact Analysis of a Novel Diagnostic Test to Assess Community-Acquired Pneumonia Etiology in the Emergency Department Setting: A Multi-Country European Study
Authors: Houshmand Hirad , Porta Camilla , Pradelli Lorenzo , Pinciroli Matteo , Sotgiu Giovanni
Published: February 2023

Background: We aimed to estimate the economic and clinical impacts of a novel diagnostic test called LIAISON® MeMed BV® (LMMBV), which can differentiate bacterial from viral infections, in patients with community-acquired pneumonia (CAP) in emergency departments. Methods: A cost-impact simulation model was developed to investigate the financial consequences of the introduction of LMMBV into the standard of care (SOC) diagnostic process in Italy, Germany, and Spain. Clinical outcomes were expressed as antibiotic patients and days saved, reduced hospital admissions, and shortened hospital length of stay (LOS). Cost savings were evaluated from the perspectives of third-party payers and hospitals. A deterministic sensitivity analysis (DSA) was carried out. Results: LMMBV was associated with a reduction in antibiotic prescriptions, treatment duration, and LOS. Furthermore, the adoption of LMMBV would allow savings per patient up to EUR 364 and EUR 328 for hospitals and EUR 91 and EUR 59 for payers in Italy and Germany, respectively. In Spain, average savings per patient could reach up to EUR 165 for both payers and hospitals. Savings were most sensitive to test accuracy, with DSA confirming the robustness of the results. Conclusions: Combining LMMBV with the current SOC diagnostic process is expected to provide clinical and economic benefits in Italy, Germany, and Spain.
Examining the Role of Self-Reliance, Social Domination, Perceived Surveillance, and Customer Support with Respect to the Adoption of Mobile Banking
Authors: Asif Mohammad , Khan Mohammed Arshad , Alhumoudi Hamad , Wasiq Mohammad
Published: February 2023

Purpose: This article aims to investigate the main drivers of mobile banking among Delhi–NCR consumers. The TAM (technological acceptance model) was used as a framework for this study. Only a few studies have looked at how online banking users in India plan to use other similar services, such as m-banking. In order to do this, a theoretical model was made using the technology acceptance model. This model was then expanded to include the factors that make m-banking users more likely to use mobile banking. These adoption factors include the feeling of being watched, the ability to do things on your own with a mobile device, social dominance, and the role of customer support as a mediator. The use of m-banking is the thing that matters. Scope: In the last two decades, digital mobile devices have become the primary preferred method of consumer communication. Throughout the past year, mobile banking has become increasingly popular. The increasing number of smartphones in use, as well as the government’s push for cashless transactions, provide an opportunity for the Indian banking industry to rapidly expand its usage of mobile and online banking. Methodology: The data were collected through a structured questionnaire distributed to 376 respondents from different sustainable investment classes. The use of convenience sampling was imposed. Structure equation modeling (SEM), reliability, convergence, discriminate validity, and model fitness were achieved through SmartPLS 3. Findings: The study found that the adoption factors had a significant impact on perceived surveillance, mobile self-reliance, and social domination and mediating role of customer support to use mobile banking. These latest findings will inform banks and financial institutions on the rise of m-banking in India, as well as provide insight into digital banking channels and add to the literature on the topic of digital banking adoption.
Relationship between Urban Environmental Components and Dengue Prevalence in Dhaka City—An Approach of Spatial Analysis of Satellite Remote Sensing, Hydro-Climatic, and Census Dengue Data
Authors: Kamal A. S. M. Maksud , Al-Montakim Md. Nahid , Hasan Md. Asif , Mitu Mst. Maxim Parvin , Gazi Md. Yousuf , Uddin Md. Mahin , Mia Md. Bodruddoza
Published: February 2023

Dengue fever is a tropical viral disease mostly spread by the Aedes aegypti mosquito across the globe. Each year, millions of people have dengue fever, and many die as a result. Since 2002, the severity of dengue in Bangladesh has increased, and in 2019, it reached its worst level ever. This research used satellite imagery to determine the spatial relationship between urban environmental components (UEC) and dengue incidence in Dhaka in 2019. Land surface temperature (LST), urban heat-island (UHI), land-use–land-cover (LULC), population census, and dengue patient data were evaluated. On the other hand, the temporal association between dengue and 2019 UEC data for Dhaka city, such as precipitation, relative humidity, and temperature, were explored. The calculation indicates that the LST in the research region varies between 21.59 and 33.33 degrees Celsius. Multiple UHIs are present within the city, with LST values ranging from 27 to 32 degrees Celsius. In 2019, these UHIs had a higher incidence of dengue. NDVI values between 0.18 and 1 indicate the presence of vegetation and plants, and the NDWI identifies waterbodies with values between 0 and 1. About 2.51%, 2.66%, 12.81%, and 82% of the city is comprised of water, bare ground, vegetation, and settlement, respectively. The kernel density estimate of dengue data reveals that the majority of dengue cases were concentrated in the city’s north edge, south, north-west, and center. The dengue risk map was created by combining all of these spatial outputs (LST, UHI, LULC, population density, and dengue data) and revealed that UHIs of Dhaka are places with high ground temperature and lesser vegetation, waterbodies, and dense urban characteristics, with the highest incidence of dengue. The average yearly temperature in 2019 was 25.26 degrees Celsius. May was the warmest month, with an average monthly temperature of 28.83 degrees Celsius. The monsoon and post-monsoon seasons (middle of March to middle of September) of 2019 sustained higher ambient temperatures (>26 °C), greater relative humidity (>80%), and at least 150 mm of precipitation. The study reveals that dengue transmits faster under climatological circumstances characterized by higher temperatures, relative humidity, and precipitation.
Kinesio Taping as a Therapeutic Tool for Masticatory Myofascial Pain Syndrome—An Insight View
Authors: Alqahtani Ahmed Shaher , Parveen Sameena
Published: February 2023

Myofascial pain syndrome (MPS) is thought to stem from masticatory muscle hypersensitivity. Masticatory myofascial pain syndrome (MMPS) is characterized by multiple trigger points (MTrPs), also known as hyperirritable points, in taut bands of affected muscles, regional muscle pain, or referred pain to nearby maxillofacial areas like teeth, masticatory muscles or the temporomandibular joint (TMJ). Muscle stiffness, reduced range of motion, muscle weakening without atrophy, and autonomic symptoms may accompany regional discomfort. Multiple treatments have been utilized to reduce trigger points and mandibular function restrictions. As a result of these incapacitating symptoms, MMPS can significantly impair many elements of quality of life. The application of Kinesio tape (KT) is a non-invasive method of treating dormant myofascial trigger points. Utilizing the body’s innate capacity for self-repair, this technique entails taping specific regions of the skin. KT alleviates discomfort, decreases swelling and inflammation, enhances or suppresses motor function in the muscles, stimulates proprioception, promotes lymphatic drainage, stimulates blood flow, and expedites tissue recovery. However, studies conducted to assess its effects have frequently yielded contradictory results. To the best of our knowledge, just a few research has looked into the therapeutic effects of KT on MMPS. The purpose of this review is to determine the efficacy of KT as a therapeutic tool for regular treatment or as an adjunct to existing therapy for MMPS based on the evidence presented in this review. To establish KT as a reliable independent treatment option, additional research is necessary to confirm the efficacy of KT techniques and applications, specifically randomized clinical trials.
Analysis and Evaluation of Dental Caries in a Mexican Population: A Descriptive Transversal Study
Authors: Moreno-Barrera Alejandro , Morales-Ruiz Pedro , Ribas Pérez David , Flores-Fraile Javier , Castaño-Seiquer Antonio
Published: February 2023

Oral diseases are an important public health problem owing to their high prevalence and strong impact on people, particularly in disadvantaged populations. There is a strong relationship between the socioeconomic situation and the prevalence and severity of these diseases. Mexico is among the countries with a higher frequency range in oral diseases, highlighting dental caries, which affect more than 90% of the Mexican population. Materials and method: A cross-sectional, descriptive, and observational study was carried out in 552 individuals who underwent a complete cariogenic clinical examination in different populations of the state of Yucatan. All individuals were evaluated after providing informed consent and with the consent of their legal guardians for those under legal age. We used the caries measurement methods described by the World Health Organization (WHO). Prevalence of caries, DMFT, and dft indexes were measured. Other aspects were also studied, such as oral habits and the use of public or private dental services. Results: The prevalence of caries in permanent dentition was 84%. Moreover, it was found to be statistically related to the following variables: place of residence, socioeconomic level, gender, and level of education (p < 0.05). For primary teeth, the prevalence was 64% and there was no statistical relation with any of the variables studied (p > 0.05). Regarding the other aspects studied, more than 50% of the sample used private dental services. Conclusions: There is a high need for dental treatment in the population studied. It is necessary to develop prevention and treatment strategies considering the particularities of each population, driving collaborative projects to promote better oral health conditions in disadvantaged populations.
How Does a Company’s ESG Performance Affect the Issuance of an Audit Opinion? The Moderating Role of Auditor Experience
Authors: Wang Xin , Song Xiayun , Sun Mingyang
Published: February 2023

Green economic development is a new growth point for China’s economy. The reduction in environmental pollution and the practice of social responsibility are strongly advocated by society. ESG (environment, society, governance) is a new concept considering how companies achieve sustainable development. Do auditors pay attention to corporate ESG when making opinion decisions? This paper examines how ESG performance affects audit opinion decisions. The results show the following: (1) The better the ESG performance is, the lower the probability of a modified audit opinion on the part of the auditor will be. (2) Consideration of the auditor experience indicates that auditors who lack experience rely more heavily on information about a corporate ESG performance to make their opinion decisions. (3) The mechanism test demonstrated that a sound ESG performance improves the quality of its financial reporting, which, in turn, reduces the probability of the auditor issuing a modified audit opinion. These conclusions remain robust after considering a number of tests, such as changing variable measures and endogeneity issues. This research expands the study of the economic consequences of ESG from an audit perspective, providing new evidence regarding the importance that corporate management places on ESG performance and how market intermediaries use ESG information.
Multicultural Identity Integration versus Compartmentalization as Predictors of Subjective Well-Being for Third Culture Kids: The Mediational Role of Self-Concept Consistency and Self-Efficacy
Authors: Mosanya Magdalena , Kwiatkowska Anna
Published: February 2023

Globalization has resulted in an exponential increase in the number of Third Culture Kids (TCKs), defined as being raised in a culture other than that of their parents (or the passport country) and meaningfully interacting with different cultures. Inconsistencies regarding the effect of multicultural and transient experiences on well-being exist in the psychological literature. We aimed to reveal associations between multicultural identity configurations (integration, categorization, compartmentalization) and well-being with the mediating role of self-concept consistency and self-efficacy. Participants (n = 399, M = 21.2 years) were students at an international university in the United Arab Emirates. We used the Multicultural Identity Integration Scale, the Berne Questionnaire of Subjective Well-Being, the General Self-Efficacy Scale, and the Self-Consistency Subscale from the Self-Construal Scale. The findings suggest that not merely exposure to diversity but also internal integration versus identity compartmentalization moderate the well-being of TCKs. We explained such mechanisms via partial mediation of self-consistency and self-efficacy. Our study contributed to a better understanding of the TCKs’ identity paradigm and pointed to multicultural identity integration as vital to TCKs’ well-being via its effect on self-consistency and self-efficacy. Conversely, identity compartmentalization decreased well-being via a reduction in the sense of self-consistency.
Effects of Medical Education Program Using Virtual Reality: A Systematic Review and Meta-Analysis
Authors: Kim Hyeon-Young , Kim Eun-Young
Published: February 2023

Several studies have examined the effect of virtual reality (VR) education. However, they are mostly systematic reviews or meta-analyses focusing on doctors and residents; they fail to consider VR medical education for a broader range of learners. We evaluated the effectiveness of VR education for health professionals and identified the essential features of education. Randomized controlled trials published from January 2000 to April 2020 were identified from PubMed, Embase, CINAHL, and the Cochrane Library (n = 299). The randomized studies’ bias risk was evaluated using Cochrane’s Risk of Bias tool. Meta- and subgroup-analyses were conducted using Review Manager 5.4.1. The overall effect was measured using Hedges’ g and determined using Z-statistics (p < 0.05). Heterogeneity was assessed using X2 and I2 statistics. Among the identified records, 25 studies were selected through systematic review, and 18 studies were included in the meta-analysis. We identified a significant improvement in the VR group’s skill and satisfaction levels, and that less immersive VR was more efficacious for knowledge outcomes than fully immersive VR. Maximizing the advantages of VR will increase learning opportunities and complement the limited clinical experience, thus improving medical services. A systematic and efficient VR medical education program will greatly enhance learners’ core competencies.
Impact of Functional Training on Functional Movement and Athletic Performance in College Dragon Boat Athletes
Authors: Wu Chichong , Cheong Manwai , Wang Yan , Wang Xiuqiang , Zhang Qingwen , Li Minghui , Lei Siman
Published: February 2023

Functional training has become a popular training method in different sports, yet limited studies have focused on paddle sports. The purpose of this study was to evaluate the effects of functional training on functional movement and athletic performance in college dragon boat athletes. A total of 42 male athletes were divided into 2 groups: a functional training (FT) group (n = 21, 21 ± 1.47 years) and a regular training (RT) group (n = 21, 22 ± 1.50 years). The FT group participated in an 8-week (16-session) functional-training program, while the RT group trained with strength-training sessions. Functional movement screen (FMS), Y-balance test (YBT) and athletic performance evaluations were conducted before and after the intervention. Repeated measure ANOVA and t-test evaluations were employed to examine differences for both groups. The FT group was significantly improved in FMS scores (F = 0.191, p < 0.001) and YBT scores (F = 2.59, p = 0.027), and it also showed significantly improved muscular fitness (pull-ups: F = 0.127, p < 0.001; push-ups: F = 1.43, p < 0.001) and rowing speed (F = 4.37, p = 0.004). It is recommended to include functional training as a part of training and routine exercise, as it appears to be an effective way of improving FMS and athletic performance in paddle sports.
Coastal Flooding Hazard, Exposure, and Readiness of Buildings in Hong Kong in 2080–2100, and the Implications for Real Estate Management
Authors: Singh Minerva , Cai Xin
Published: February 2023

Coastal flooding has been a significant hazard in Hong Kong. Influenced by climate change, extreme coastal flooding events have been frequently observed in the past decades. Nowadays, the real estate sector has increasingly recognized the significance of managing future coastal flooding risks. However, there are few relevant Geographic Information System (GIS)-based assessment tools and studies about future scenarios. Against this background, this study aims to understand the risk and readiness of properties in Hong Kong for future coastal flooding and to reduce the gap in the risk management decision-making process. This study included the return period, sea level rise, tide activity, and storm surge as the main factors for estimating the frequency and magnitude of coastal flooding events. The estimation and other geospatial data were calculated to describe the exposure, hazard, and readiness of every building in Hong Kong. Based on this risk data of buildings, clustering analysis was adopted to create clusters representing different building risk profiles. The results highlight that there will be 16.3% and 24.7% of buildings in Hong Kong exposed to coastal flooding under Shared Socioeconomic Pathway (SSP) 8.5 and SSP 4.5, respectively, and 2.5% of them will have an extremely high hazard level. This study then constructed an indicator-based assessment model for the real estate sector regarding future coastal flooding risks. Classifying the buildings based on characteristics of their risk profile obtained eight clusters, with clusters 1 and 2 having high risk and low readiness, and clusters 7 and 8 having low risk and low to medium readiness. In addition, distinct spatial patterns were found between the clusters that have low and high readiness of green infrastructure. Therefore, recommendations for the policymaker, planner and companies were provided based on their local situation. Specifically, the discussion suggests that although Yuen Long is an area that has a relatively larger number of high-risk buildings, clusters 3 and 4 in Yuen Long have more potential for adopting various loss mitigation measures. However, clusters 5 and 6 in the city center are more recommended to adopt financial tools and small-scale nonstructural improvements.
Adding Diversity to Diiron Aminocarbyne Complexes with Amine Ligands
Authors: Saviozzi Chiara , Stocchetti Sara , Bresciani Giulio , Biancalana Lorenzo , Pampaloni Guido , Marchetti Fabio
Published: February 2023

The reactions of the diiron aminocarbyne complexes [Fe2Cp2(NCMe)(CO)(μ-CO){μ-CN(Me)(R)}]CF3SO3 (R = Me, 1aNCMe; R = Cy, 1bNCMe), freshly prepared from the tricarbonyl precursors 1a–b, with primary amines containing an additional function (i.e., alcohol or ether) proceeded with the replacement of the labile acetonitrile ligand and formation of [Fe2Cp2(NH2CH2CH2OR’)(CO)(μ-CO){μ-CN(Me)(R)}]CF3SO3 (R = Me, R’ = H, 2a; R = Cy, R’ = H, 2b; R = Cy, R’ = Me, 2c) in 81–95% yields. The diiron-oxazolidinone conjugate [Fe2Cp2(NH2OX)(CO)(μ-CO){μ-CN(Me)2}]CF3SO3, 3, was prepared from 1a, 3-(2-aminoethyl)-5-phenyloxazolidin-2-one (NH2OX) and Me3NO, and finally isolated in 96% yield. In contrast, the one pot reactions of 1a-b with NHEt2 in the presence of Me3NO gave the unstable [Fe2Cp2(NHEt2)(CO)(μ-CO){μ-CN(Me)(R)}]CF3SO3 (R = Me, 4a; R = Cy, 4b) as unclean products. All diiron complexes were characterized by analytical and spectroscopic techniques; moreover, the behavior of 2a–c and 3 in aqueous media was ascertained.
Identification and Functional Characterization of General Odorant Binding Proteins in Orthaga achatina
Authors: Ma Yu , Li Yu , Wei Zhi-Qiang , Hou Jing-Hao , Si Yu-Xiao , Zhang Jin , Dong Shuang-Lin , Yan Qi
Published: February 2023

The olfactory system in insects are crucial for recognition of host plants and oviposition sites. General odorant binding proteins (GOBPs) are thought to be involved in detecting odorants released by host plants. Orthaga achatina (Lepidoptera: Pyralidae) is one of the most serious pests of camphor trees, Cinnamomum camphora (L.) Presl, an important urban tree species in southern China. In this study, we study the GOBPs of O. achatina. Firstly, two full-length GOBP genes (OachGOBP1 and OachGOBP2) were successfully cloned according to transcriptome sequencing results, and real-time quantitative PCR measurements showed that both GOBP genes were specifically expressed in the antennae of both sexes, proposing their important roles in olfaction. Then, both GOBP genes were heterologous expressed in Escherichia coli and fluorescence competitive binding assays were conducted. The results showed that OachGOBP1 could bind Farnesol (Ki = 9.49 μM) and Z11-16: OH (Ki = 1.57 μM). OachGOBP2 has a high binding affinity with two camphor plant volatiles (Farnesol, Ki = 7.33 μM; α-Phellandrene, Ki = 8.71 μM) and two sex pheromone components (Z11-16: OAc, Ki = 2.84 μM; Z11-16: OH, Ki = 3.30 μM). These results indicate that OachGOBP1 and OachGOBP2 differ in terms of odorants and other ligands. Furthermore, key amino acid residues that bind to plant volatiles were identified in GOBPs using 3-D structure modeling and ligand molecular docking, predicting the interactions between the GOBPs and the host plant volatiles.
The Techniques of Blood Purification in the Treatment of Sepsis and Other Hyperinflammatory Conditions
Authors: Berlot Giorgio , Tomasini Ariella , Zanchi Silvia , Moro Edoardo
Published: February 2023

Even in the absence of strong indications deriving from clinical studies, the removal of mediators is increasingly used in septic shock and in other clinical conditions characterized by a hyperinflammatory response. Despite the different underlying mechanisms of action, they are collectively indicated as blood purification techniques. Their main categories include blood- and plasma processing procedures, which can run in a stand-alone mode or, more commonly, in association with a renal replacement treatment. The different techniques and principles of function, the clinical evidence derived from multiple clinical investigations, and the possible side effects are reviewed and discussed along with the persisting uncertainties about their precise role in the therapeutic armamentarium of these syndromes.
Aggressive Angiomyxoma of the Vulva: Which Is the Best Management Strategy? Description of a Case Report and Review of Literature of the Last Ten Years
Authors: Gulino Ferdinando Antonio , Gulisano Marianna , Ettore Carla , Giorlandino Alexandra , Russo Emanuele , Ettore Giuseppe
Published: February 2023

Background: Aggressive angiomyxoma is a rare mesenchymal tumour of the genital tract with a high incidence in women of reproductive age. The aim of our work is to understand which is the best management strategy for this condition, starting from the description of a rare case report up to the performance of a narrative review of the literature. Methods: We report a case of a 46-year-old woman who came to our attention because of the growth of a 10-centimetre pedunculated, non-soft, non-tender mass of the left labium majus. She underwent surgical excision, and the histologic diagnosis was aggressive angiomyxoma. Due to a lack of tumour-free margins, radicalization surgery was carried out after three months. A review of the literature of the last ten years was performed following the PRISMA statement on MEDLINE (PubMed). We obtained data from twenty-five studies describing thirty-three cases. Results: Aggressive angiomyxoma is characterized by a high recurrence rate of between 36 and 72% after surgery. There is no universal consensus about hormonal therapy, and most studies (85%) describe surgical excision followed by only clinical and radiological follow-up. Conclusion: Wide surgical excision is the gold-standard treatment for aggressive angiomyxoma, succeeded by either clinical or radiological (ultrasound or MRI) follow-up.