bluuebunny/crossref_metadata_2025 huggingface dataset:
Regulation of alternative splicing and polyadenylation in neurons
Authors: Lee Seungjae , Aubee Joseph I , Lai Eric C
Published: October 2023

Cell-type–specific gene expression is a fundamental feature of multicellular organisms and is achieved by combinations of regulatory strategies. Although cell-restricted transcription is perhaps the most widely studied mechanism, co-transcriptional and post-transcriptional processes are also central to the spatiotemporal control of gene functions. One general category of expression control involves the generation of multiple transcript isoforms from an individual gene, whose balance and cell specificity are frequently tightly regulated via diverse strategies. The nervous system makes particularly extensive use of cell-specific isoforms, specializing the neural function of genes that are expressed more broadly. Here, we review regulatory strategies and RNA-binding proteins that direct neural-specific isoform processing. These include various classes of alternative splicing and alternative polyadenylation events, both of which broadly diversify the neural transcriptome. Importantly, global alterations of splicing and alternative polyadenylation are characteristic of many neural pathologies, and recent genetic studies demonstrate how misregulation of individual neural isoforms can directly cause mutant phenotypes.
Liver regeneration after partial hepatectomy: the upper optimality estimate
Authors: Karieva V. V. , Lvov S.V.
Published: October 2023

This publication investigates one of the fundamental problems of mathematical biology, specifically the development of mathematical models for the dynamics of complex biosystems that have a satisfactory explanatory and predictable power. A necessary condition for the development of such models is to find a solution for the problem of identifying the objective principles and rules of regulation of the "cellular system", which determines among all the possibilities exactly the "real path" of its dynamics observed in the experiment.

One of the promising approaches to solving this problem is based on the hypothesis that the regulation of processes for support/restoration of the dynamic homeostasis of tissues and organs of the body occurs according to certain principles, and criteria of optimality, which have developed due to the natural selection of the body during its previous evolution.

It is quite difficult to solve this problem at the current time due to the many uncertainties in the paths of the previous evolution of the organism, the dynamics of changes in external conditions, as well as the high computational complexity of solving such a problem.

Instead of this, we have proposed a simplified formulation of the problem of searching for regulation control strategies, which gives us an upper estimate of optimality for the processes of maintaining/restoring dynamic homeostasis of the liver. The upper estimate of the optimality of regulation and testing of hypotheses for the model of liver regeneration was considered in the case of partial hepatectomy and was solved by Python software methods.

The result shows that in the case of partial hepatectomy, the liver regeneration strategies obtained in numerous experiments for the problem of the upper optimality estimate qualitatively coincide with the processes of liver regeneration that can be observed during biological experiments.

In plenty of experiments following hypotheses were also tested: how significant is the contribution of the process of controlled apoptosis, and how other processes (polyploidy, division, and formation of binuclear hepatocytes) affect the strategy of liver regeneration.
Enseñar con tecnologías digitales en la educación superior
Authors: Galán Figueroa Patricia de los Ángeles , Hernández Gómez Ronald Mauricio , Espinoza Cordero Andrea Isabel
Published: October 2023

Esta investigación tiene por objetivo analizar el nivel de uso que de las tecnologías hace el profesorado universitario, interesándose tanto por la frecuencia de uso de ellas, como por el tipo de actividades de aprendizaje en las que se utilizan. Los problemas de investigación se centraron en: ¿qué tipos de actividades de aprendizaje con tecnologías diseñan los docentes universitarios?, ¿qué tipo de tecnologías utilizan los docentes en el diseño de su enseñanza?, ¿cuál es el nivel de uso de las tecnologías digitales en los diseños del aprendizaje del profesorado universitario? Hemos diseñado el Inventario de Actividades de Aprendizaje con Tecnologías en la Universidad que fue respondido por 941 docentes andaluces. A través de él hemos identificado el tipo y frecuencia de uso que de la tecnología hace el profesorado universitario en sus materias al tiempo que hemos estudiado las actividades de aprendizaje que predominan en sus diseños del aprendizaje. Los resultados revelan una pobre integración de tecnologías en los procesos de enseñanza-aprendizaje los cuales se constituyen, esencialmente, de actividades de aprendizaje centradas en el do- cente. Hemos identificado cuatro perfiles diferenciados de docentes en función del nivel de uso que hacen de las TIC. De los cuatro, el perfil que mayor número de docentes agrupa es el que hace referencia a un uso poco frecuente de la tecnología; son docentes que emplean escasamente la tecnología y esta es de una gama muy reducida.
Knowledge Level of DAGUSIBU in Pharmacy Department Students at Health Polytechnic of Tanjung Karang
Authors: Sembiring Elma Viorentina , Hartati Ani , Julaiha Siti
Published: October 2023

There are many health problems due to lack of knowledge and understanding of how to use, store and dispose of drugs. The Indonesian Pharmacist Association (IAI) to design a program called DAGUSIBU (Get-Use-Save-Dispose). Information about DAGUSIBU is important to avoid giving wrong information from occupational pharmacy to patients. This study aims to determine Knowledge Level Profile of DAGUSIBU in Pharmacy Department Students in Health Polytechnic of Tanjung Karang 2022. This research was observational research design with a cross-sectional approach which was carried out from October to November 2022 involving 226 pharmacy students class of 2020 to 2022 in Health Polytechnic of Tanjung Karang. Data obtained by using an online questionnaire that had been tested for validity and reliability. In the aspect of getting medicine, the knowledge level pharmacy students 15.5% good, 38.9% sufficient, and 45.4% lacking. In the aspect of drug use, having a greater knowledge level of 11.1% is good; 44.7% sufficient; and 44.2% less. In the aspect of saving medicine, having a knowledge level of 9.3% is good; 40.3% sufficient; and 34.0% less. Bivariate analysis using ANOVA to find out differences of knowledge level among classes. The results of the ANOVA test showed a p-value of 0.112 so that it can be concluded that there is no significant difference in the level of DAGUSIBU knowledge between batches in Pharmacy students at Health Polytechnic of Tanjung Karang in 2022.
Efektivitas Gum Mimba (Azadirachta indica) sebagai Atraktan Ovitrap Nyamuk
Authors: Nihayah Husnatun , Purwatiningsih Purwatiningsih
Published: October 2023

Pemasangan ovitrap atau perangkap telur menjadi salah satu metode surveilans untuk pengendalian nyamuk. Adanya atraktan dengan kandungan senyawa organik yang tinggi dari gum mimba pada ovitrap diharapkan akan meningkatkan oviposisi nyamuk untuk meletakkan telurnya didalam ovitrap tersebut. Tujuan penelitian ini adalah untuk mengetahui efektivitas gum mimba sebagai atraktan ovitrap. Penelitian telah dilaksanakan sejak bulan September hingga November 2022. Larutan gum mimba dibuat dengan melarutkan serbuk gum mimba dengan air panas dengan konsentrasi 2% dan pH7. Sebanyak 130 ovitrap (65 ovitrap air kran, 65 ovitrap larutan gum mimba 2%) telah dipasang di lingkungan Sumbersari serta dilakukan pemanenan telur nyamuk yang terperangkap pada hari ke 8 pemasangan. Telur dan larva yang terperangkap kemudian ditetaskan, diidentifikasi dan analisis dengan uji Mann-Whitney. Hasil uji statistik menunjukkan adanya pengaruh jenis air ovitrap terhadap jumlah nyamuk terperangkap. Ovitrap dengan air kran dinilai lebih efektif karena memiliki nilai OI (61,54%), jumlah telur (3577), ODI (89,42) yang lebih tinggi dibandingkan dengan ovitrap berisi gum mimba (OI 36,92%, Jumlah telur 1463, ODI 60,96). Hasil identifikasi nyamuk menunjukkan spesies Aedes aegypti, Aedes albopictus, Armigeres kesseli, Culex quinquefasciatus. Kesimpulan dari penelitian ini adalah ovitrap dengan air kran lebih efektif dibandingkan dengan ovitrap dengan gum mimba sebagai media.
Literature Review on the Renovation Project of Self-Built Residential Buildings in the South Under the Low-Carbon Background
Authors: Yang Yi , Ma Xin
Published: October 2023

With the continuous exploration and research of low-carbon buildings in China, combined with foreign theoriesand practices, there are a few basic theoretical and practical projects for low-carbon construction in major cities of China. However, throughout the entire academic research, there is still no comprehensive and clear guidance for the green and low-carbon research and transformation of rural self-built houses. Therefore, the existing development of low-carbon technology for rural self-built houses has been summarized, and some prospects for the future development of rural selfbuilt houses have been summarized. It is hoped that this will have positive help for future rural low-carbon transformation.
Implementation of PERMA Model into Teaching and Learning of Generation Z
Authors: Md Khalid Norfaezah , Senom Fatiha , Muhamad Ahmad Shamsuri , Mansor Nur Marsya Fatiha , Saleh Nur Hasbuna
Published: October 2023

Teenagers and young adults (Gen Z) experience high rates of depression and anxiety, and one of the contributing factors is related to academic stress. Gen Z has unique characteristics, and technology has a powerful influence on the learning of Gen Z. Notwithstanding, evidence-based learning remains limited pertaining to the use of technology to alleviate the academic stress for Gen Z learning. Hence, to address this issue, this study integrates a well-being model, the Positive, Engagement Relationships, Meaning and Achievement (PERMA) Model into a technology-based teaching and learning approach, by introducing the Happy Capsule as a kit to promote learning engagement. Happy Capsule is a combination of five digital tools which are Padlet, Kahoot!, Wiki, e-portfolio, and an online learning style test. Employing the Participatory Action Research, this paper explores the experiences of 50 first-year university students’ in learning with Happy Capsule for over 14 weeks. Thematic analysis was used and four main themes emerged, namely self-management, engagement in learning, emotional aspects, and soft skills. The findings emphasize that digital learning has become a necessity to fulfil students’ learning needs, especially in the higher education setting. The study found that the implementation of positive emotion, engagement, relationship, meaning, and achievement elements in teaching and learning helps educators in designing more effective learning and assessment strategies to meet the current demands as well as to cater to students’ needs, styles, and preferences. In addition, it also increases motivation, enthusiasm, and builds good communication skills among students. Future research may focus on conducting more Action Research to improve practice by integrating various digital tools in teaching and learning in diverse contexts.
A comparison of COVID-19 incidence rates across six European countries in 2021
Authors: Padget Michael , Adam Pauline , Dorfmuller Marina , Blondel Clara , Campos-Matos Ines , Fayad Myriam , Mateo-Urdiales Alberto , Mesher David , Pistol Adriana , Rebolledo Javiera , Riccardo Flavia , Riess Maximilian , Rusu Lavinia Cipriana , Che Didier , Coignard Bruno ,   COVID-19 Study group
Published: October 2023

International comparisons of COVID-19 incidence rates have helped gain insights into the characteristics of the disease, benchmark disease impact, shape public health measures and inform potential travel restrictions and border control measures. However, these comparisons may be biased by differences in COVID-19 surveillance systems and approaches to reporting in each country. To better understand these differences and their impact on incidence comparisons, we collected data on surveillance systems from six European countries: Belgium, England, France, Italy, Romania and Sweden. Data collected included: target testing populations, access to testing, case definitions, data entry and management and statistical approaches to incidence calculation. Average testing, incidence and contextual data were also collected. Data represented the surveillance systems as they were in mid-May 2021. Overall, important differences between surveillance systems were detected. Results showed wide variations in testing rates, access to free testing and the types of tests recorded in national databases, which may substantially limit incidence comparability. By systematically including testing information when comparing incidence rates, these comparisons may be greatly improved. New indicators incorporating testing or existing indicators such as death or hospitalisation will be important to improving international comparisons.
USING ELEMENTS OF GAMIFICATION IN INTELLIGENT LEARNING SYSTEMS: ONTOLOGICAL ASPECT
Authors: Tkachenko Kostiantyn , Tkachenko Olha , Tkachenko Oleksandr
Published: October 2023

The article considers an ontological approach to the creation and use of intelligent learning systems with elements of gamification. It is expedient to use developed multi-level ontological model in the implementation of learning processes in higher educational institutions. An ontological modeling of the intelligent learning systems based on multidimensional models is proposed. The proposed approach makes it possible to develop the multi-level ontological model of any intelligent learning system that fully reflects the pragmatics of the studied subject area. The proposed multi-level ontological model of the intelligent learning system with elements of the gamification captures and structures knowledge common to the subject area that is being studied. This allows you to reuse it as the basis of a single knowledge model, which ensures logical consistency between individual ontologies when combined to create learning content (for example, online course) with a wider list of the topics and tasks. The application of the ontological approach is an effective way to design and develop the intelligent learning systems. The constructed individual ontological models (of learning content, of tests, ontology of student results and actions, of student knowledge assessments, of the gamification components) contribute to the design of a unified information learning environment (learning content), within which intelligent learning systems that use the gamification elements. The multi-level ontological model proposed in the work helps to increase the efficiency of learning processes, maintaining interest and motivation to study the proposed learning content containing elements of gamification. The result of using the elements of gamification and the ontological modeling in the intelligent learning systems is the ability to make the necessary adjustments to the goals and objectives of the learning process, the learning process, the course of learning, the requirements for the level and competence of students.
A PERFORMANCE COMPARISON OF SORTING ALGORITHMS IN DIFFERENT PROGRAMMING LANGUAGES
Authors: Trofymenko Olena , Prokop Yuliia , Chepurna Olena , Korniichuk Mykola
Published: October 2023

Sorting, as one of the basic algorithms, has a wide range of applications in software development. As the amount of processed data grows, the need for fast and efficient data sorting increases significantly. There are many sorting algorithms and their extensions. However, choosing the best and most versatile among them is impossible. All these algorithms have their specifics, which determine the scope of their effective use. Therefore, the problem of deciding the optimal algorithm for certain specific conditions is relevant. This choice is often a non-trivial task, and an unsuccessful choice of algorithm can cause difficulties with data processing performance. To determine which algorithm will be the best in a particular situation, you need to analyse all the factors that affect the operation of algorithms: the size and structure of the data set, the range of element values, the form of access (random or sequential), the orderliness, the amount of additional memory required to execute the algorithm, etc. In addition, different algorithms have different performance in different programming languages. The study analyses the advantages and disadvantages of nine popular sorting algorithms (Bubble, Insertion, Selection, Shell, Merge, Quick, Counting, Radix, and Heap) due to their specifics and limitations on their possible use. The performance of these algorithms implemented in four popular programming languages (C++, C#, Java and JavaScript) is tested. We experimentally discovered that the performance of sorting algorithms differs depending on the programming language. The applied aspect of the study is that its conclusions and results will allow developers to choose the best algorithm for a particular programming language, depending on the size, range, structure, etc. of the data set to be sorted. Considering this is significant when we have to sort large amounts of data in search engines, scientific and engineering applications. After all, the sorting algorithm's efficiency significantly affects the system's overall performance.
Assessing Artificial Recharge on Groundwater Quantity Using Wells Recharge
Authors: Hassan Waqed H. , Ghazi Zainab N.
Published: October 2023

In arid and semi-arid countries like Iraq, which suffer from water scarcity due to the effects of climate change and decreased surface water flow, groundwater is considered a vital source of irrigation water. This study is concerned with the influence of artificial recharge on the rehabilitation of the unconfined aquifer called Al-Dibdibba, located between the cities of Najaf and Kerbala in central Iraq around 31°550′ N and 32°450′ N and 43°300′ E and 44°300′ E. Due to excessive groundwater pumping rates for irrigation, this aquifer has suffered from groundwater decline and increased salinization during the previous 20 years. By establishing a conceptual model in the groundwater modeling system software (GMS), a numerical model was made to simulate groundwater flow. Artificial recharge using recycled water (tertiary treatment) from Kerbala's primary WWTP was carried out using 25 injection wells. The model was calibrated against historical and observed water level data for periods from 2016 to 2017. Three scenarios to predict how the aquifer would act with artificial recharge of 5%, 8%, and 10% from the total daily outflow of the WWTP in Kerbala (100000 m3/day) were studied. The calibration model met the observed values of groundwater levels with R2 = 0.989 for steady-state simulations and R2 = 0.987 for transient simulations. In the final analysis of the simulation, the results show that the maximum predicted groundwater level was raised by the injection of treated water through 25 wells by 1.05 m for 5000 m3/day, 2 m for 8000 m3/day, and 3 m for 10,000 m3/day recharge pumping rates. In addition, if water were pumped into the aquifer, it might support the development of agricultural lands covering more than 93 km2. So, artificial recharge can be considered one of the important solutions to adaptation to the effects of climate change and desertification in Iraq. Doi: 10.28991/CEJ-2023-09-09-010 Full Text: PDF
Fundamental Challenges and Management Opportunities in Post Disaster Reconstruction Project
Authors: Altaie Meervat R. , Dishar Marwa Makki , Muhsin Ibrahim F.
Published: October 2023

The study examines the root causes of delays that the project manager is unable to resolve or how the decision-maker can identify the best opportunities to get over these obstacles by considering the project constraints defined as the project triangle (cost, time, and quality) in post-disaster reconstruction projects to review the real challenges to overcome these obstacles. The methodology relied on the exploratory description and qualitative data examined. 43 valid questionnaires were distributed to qualified experienced engineers. A list of 49 factors causes was collected from previous international and local studies. A Relative Important Index (RII) is adapted to determine the level of importance of each sub-criterion in the four main criteria (scope, time, cost, and quality) to represent the causing changes in projects. The concluded 13 important factors represent the challenges faced by managers. This process requires active participation in the management role to overcome potential delays that face a great challenge and cause huge waves of displacement that affect the Iraqi economy and lead to social and environmental modifications. Reconstruction projects create jobs, improve the quality of life, and encourage people to return to their homes and rebuild their cities. So, unlocking local potential is the key to sustainable rebuilding in Iraq. Doi: 10.28991/CEJ-2023-09-09-05 Full Text: PDF
3 ve 4. sınıf Türkçe ders kitaplarındaki metinlerin Ateşman ve Çetinkaya-Uzun okunabilirlik formüllerine göre incelenmesi
Authors: YOKUŞ Yusufhan , ÖRGE YAŞAR Funda
Published: October 2023

Öğrencilerin okuma, matematik ve fen alan becerileri ile okuryazarlıklarını ölçmek amacıyla Ekonomik İşbirliği ve Kalkınma Örgütü (OECD) tarafından geliştirilen Uluslararası Öğrenci Değerlendirme Programının (PISA) 2018 yılı verilerine göre, öğrencilerimizin okuma becerilerinde görülen artışa rağmen sonuçların henüz istenilen seviyede olmadığı aşikârdır. Okuma becerisi; okunabilirlik, anlaşılabilirlik ve okunaklık kavramlarını içeren bir süreçtir. Bu kavramlardan biri olan okunabilirlik, metinlerin kolay mı yoksa zor mu anlaşıldığını belirlemek amacıyla kullanılabilecek bir kıstastır. Bu kıstası Türkçe ders kitaplarına metin seçerken dikkate almak, öğrencilerin okuma becerilerini geliştirmede yararlı olacaktır. Okunabilirlik düzeylerinin belirlenmesinde çeşitli formüller kullanılmaktadır. Bu çalışma, Türkçe dersi kapsamında 3 ve 4. sınıflarda okutulan Türkçe ders kitaplarındaki bilgilendirici ve hikâye edici metinlerin Ateşman ile Çetinkaya-Uzun okunabilirlik formüllerine göre incelenmesini amaçlamaktadır. Bu bağlamda Millî Eğitim Bakanlığı tarafından yayımlanan ve 2022-2023 eğitim öğretim yılında 3 ve 4. sınıflarda okutulan Türkçe ders kitaplarında yer alan bilgilendirici ve hikâye edici metinler tespit edilmiş, şiir ve dinleme metinleri ise kapsam dışı tutulmuştur. Ardından metinler, Ateşman ve Çetinkaya-Uzun okunabilirlik formülleri ile incelenerek ilgili metinlerin okunabilirlik puanları ve okunabilirlik düzeyleri saptanmıştır. Çalışma, nitel araştırma yöntemlerinden doküman analizini temel alan ve betimsel niteliklere dayanan tarama modelinde yapılandırılmıştır. İncelenen 3 ve 4. sınıf Türkçe ders kitaplarındaki metinlerin Ateşman Okunabilirlik Formülüne göre “orta güçlükte”, Çetinkaya-Uzun Okunabilirlik Formülüne göre “eğitsel okuma” düzeyinde olduğu saptanmıştır. Türkçe ders kitaplarında sadece “kolay” veya “orta güçlükte” metinler yerine tüm düzeylerde metinlere yer vermek, öğrencilerin okuma becerisini geliştirmek adına yararlı olacaktır.
Cumhuriyet Dönemi Şiirlerinde Halk Hikâyesi Kahramanı “Kerem”
Authors: DİNÇER Fatih
Published: October 2023

Halk hikâyeleri geleneksel toplumun sözlü kültürü içinde öne çıkan anlatı türlerindendir. Türk halk edebiyatı içinde kahramanlık, aşk, savaş gibi temalar etrafında söylene gelmiş yazıya dökülmüş çok çeşitli halk hikâyeleri yer alır. Kerem ile Aslı hikâyesi bu örneklerden sadece biridir. Türk toplumunda çok geniş kitlelere ulaşmış, anlatılagelmiş bu halk hikâyesi, modern anlatı geleneğinin yeni tür ve konularıyla diğer geleneksel anlatılar gibi geri plana itilmiş gibidir. Fakat Cumhuriyet döneminin ilk yılları bu bakımdan incelendiğinde durumun pek de öyle olmadığı anlaşılır. Özellikle Anadolu romantizminin, memleket edebiyatının hâkim tema haline gelmesi, Anadolu’nun geleneksel anlatılarının da yeni bir duyuşla şiire taşınmasında önemli bir rol oynar. Geleneksel anlatının kahramanları, bir şekilde modern anlatının yeniden kurgulandığı, yeni çağrışımlar tasarlama peşine düşüldüğü evrede, uyarlanmış şekillerde yaşamaya devam eder. Başta Kerem olmak üzere Kerem ile Aslı hikâyesinin kahramanları da böyle bir dönüşümle Türk şiirinin tem ve çağrışımları içinde şairlerin muhayyilesinde dönemin hayat tarzı ve düşüncelerine göre farklı görünümler kazanarak yaşamaya devam eder. Türk milletinin ortak muhayyilesinden doğan ve kendi yaşayışının ürünü olan Kerem gibi bir âşık tipinin modernleşme serüveni içinde yol alan şairlerin ilham kaynağına dönüşürken, nasıl değişimler gösterdiği üzerinde durulması gereken bir konudur. Bu çalışma, Kerem’e yazılmış yahut Kerem’in bir imaj olarak kullanıldığı şiirler çerçevesinde bir tasnifleme ve inceleme amacı taşır.
Çeviribilimde James S. Holmes’ü yeniden anlamak: Viyana Çevresi’nin mantıksal pozitivizmi bağlamında Holmes’ün ampirizm konseptinin incelenmesi
Authors: ÇELİKAY Mustafa Kartal
Published: October 2023

James S. Holmes ismi çeviribilim içerisinde gerek alanın kurucuları arasında yer alması gerekse de alanın hem kuramsal hem de uygulamalı alanda gelişimine dair önemli saptamalarda bulunması ile önemli bir konumda bulunmaktadır. Ancak mevcut literatür tarandığında Holmes’ün ağırlıklı olarak 1972 tarihli Çeviribilimin Adı ve Doğası isimli çalışmasına sıkışıp kaldığı gözlemlenebilmektedir. Bu çalışmada Holmes’ün tüm yayınlarını içeren Çevrilmiş! Edebi Çeviri ve Çeviribilim Üzerine Makaleler isimli kitabı detaylıca incelenmiş ve onun alan için yaptığı ampirik bir disiplin tanımının altında önemli bir boyutta 20. yüzyıl bilim ve bilim felsefesi anlayışının şekillenmesinde gözle görülür bir rolü olan Viyana Çevresi’nin mantıksal pozitivizm akımının yattığı saptanmıştır. Bu iddianın en önemli dayanağı Holmes’ün kendisinin bizzat verdiği örnekte Carl G. Hempel’i kullanmış olmasıdır. Hempel’in kendisi de Viyana Çevresi’nin önemli bir üyesi olarak dikkat çekmektedir. Çalışmadaki ana iddianın bir başka dayanak noktasını ise Viyana Çevresi’nin birçok farklı disiplinden bilim insanı ve filozofu ortak bir amaç uğruna birleştirme amacına paralel olacak bir şekilde Holmes de çeviribilim için benzer amaçlar doğrultusunda dönemin en önemli isimlerini Amsterdam’da düzenlediği sempozyumlarda bir araya getirmiştir. Holmes birleşilmiş bir hareket alanını, kullanılacak ortak bir mantık dilinde görmüştür. Bu yüzden Holmes’ün 1972’deki çalışmasının dışındaki çalışmalarında kullandığı sembolik formülizasyon dili, Viyana Çevresi’ndeki anahtar figürlerin kullandığı mantık diliyle karşılaştırılmış ve bu noktada da önemli benzerlikler saptanmıştır. Holmes’ün bilimsel kökenlerinin incelenmesi neticesinde onu alan içerisinde yeniden anlamak, onun her zaman asıl amacı olan meta-kuramsal tartışma zemininin kurulabilmesini de sağlayacaktır. Böylelikle kendisinin de zamanında öngördüğü ve hâlâ günümüz çeviribilim içerisindeki çalışmalarda görülebilen bazı sorun saptamalarının da giderilebileceği düşünülmektedir.
Адаптаційний потенціал серцево-судинної системи у школярів пубертатного віку
Authors: Шевчук Тетяна , Романюк Альона , Апончук Людмила , Романюк Віктор , Біла Богдана
Published: October 2023

. В роботі проведено дослідження фізичного розвитку та адаптаційних резервів серцево-судинної системи на початку та під час закінчення пубертатного періоду. Для цього обрано контингент обстежуваних 10–11 років (препубертатний період) та 15–16 років (постпубертатний період). Отримані результати показали, що за центильними таблицями фізичний розвиток школярів у препубертатному періоді був гіршим, ніж у постпубертатний період. У 15–16 років зафіксовано більше осіб з дуже високим, високим та вище середного рівнями фізичного розвитку. Діти перед статевим дозріванням мають мезоморфну статуру. В кінці пубертату – з різним соматотипом. У хлопців відмічено дисгармонійний фізичний розвиток з відставанням росту (брахіморфний тип), а у дівчат переважають процеси витягування (доліхоморфний тип).
New record of Hylobius (Callirus) pinastri (Gyllenhal, 1813) (Coleoptera, Curculionidae) in Volyn Region
Authors: Nazarenko Vitaly , Sukhomlin Kateryna , Zinchenko Oleksandr , Trush Tatiana
Published: October 2023

H. pinastri (small pine weevil) inhabits almost the entire Palearctic. Lives in coniferous and mixed forests, mainly in wet spruce forests on Picea abies, rarely Pinus sylvestris (Pinaceae). Larvae develop in bark of stumps, lower parts of trunks and cutted woods. In Ukraine, this species occurs mainly in the north-western part (Volyn, Rivne, Zhytomyr, Lviv, Ivano-Frankivsk regions) and one record was published from the east of the country (Kharkiv region). In the Volyn region, one specimen of H. pinastri was found in the in the Shatskyi National Nature Park.

The collection of material was carried out by counting animals on six test plots from 05.07.2022 to 09.25.2022. Three Barber traps were placed in each trial area. The traps were located at a distance of 50 m from each other.
New finds of H. pinastri were registered in the Kivertsi National Park "Tsumanska Pushcha". 1 female was collected in a pine forest; 3 females and 2 males – on the border between the spruce forest and dry spruces; 1 male and 1 female – in dry spruces forest; 5 females was collected in a spruce forest with mixed hardwoods.
The paper provides a key for the identification of two closely related species, H. pinastri and H. abietis.
Current finds of this species confirm previously published data on its occurrence in the Volyn region and the contiguity of this species to spruce stands. It can be expected that H. pinastri can be found in other places of Ukraine.
Türkiye’de Uygulanan Vergi Affı Yasalarının Muhasebe Kayıtlarına Yansıması ve TFRS/TMS Çerçevesinde Değerlendirilmesi
Authors: SOYALP SOLAKOĞLU Berrak , KIYMETLİ ŞEN İlker
Published: October 2023

Türkiye Cumhuriyeti’nde ilk vergi affı 17.05.1924 tarihinde yasallaştırılmıştır. Bu tarihten günümüze kadar 36 vergi affı yasası düzenlenmiş olup Resmi Gazete’de yayınlanmıştır. 2011 yılından itibaren uygulamaya konmuş olan vergi affı yasaları mevzuatı, mükelleflerin Gelir Vergisi, Kurumlar Vergisi ve Katma Değer Vergisi (KDV) yönünden matrah artırımı düzenlemesinin dışında, stok ve kasa/alacak affını da barındırmaktadır. Devlet yönetimi bu durumların hepsini ya da birkaçını kapsayacak şekilde stok ve kasa/alacak affı yasalarını belirli periyotlarla çıkarabilmektedir. Söz konusu af yasaları; hem işletmelere ait ticari mal, demirbaş, makine ve teçhizat, ortaklardan alacaklar ve kasa mevcudunun düzeltilerek yasal kayıtlar altına alınması, hem de bağımsız denetim ve Türkiye Muhasebe ve Finansal Raporlama Standartları (TMS/TFRS)’na göre hazırlananan finansal tabloların düzenlenmesi açısından büyük öneme sahiptir. Bu çalışmanın amacı, Türkiye’de uygulanan stok ve kasa/alacak affı uygulamalarını 213 sayılı Vergi Usul Kanunu (VUK), TMS/TFRS ve bağımsız denetim açısından incelemektir. VUK’da amaç vergi matrahının doğru bir şekilde tespiti iken, TMS/TFRS’de finansal tabloların gerçeğe uygun, ihtiyaca uygun ve karşılaştırılabilir olarak sunulmasıdır.
La Conciliación en los delitos de peculado
Authors: Sarango Albiño Juan Carlos , Sánchez O Danny Xavier
Published: October 2023

La conciliación en los delitos de peculado no está concebida en la legislación penal ecuatoriana. Sin embargo, la doctrina sí concibe la misma, como método alternativo de solución de conflictos ante delitos de peculado. El trabajo investigativo desarrolla los principios de justicia restaurativa y la mínima intervención penal, además forma argumentos sobre la necesidad y proporcionalidad de la pena. El objetivo es analizar la viabilidad de la conciliación en delitos de peculado. Las principales interrogantes se presentan en base a: ¿Cuáles son los principales fundamentos doctrinarios que desarrolla en la justicia restaurativa?, ¿Cómo el principio de mínima intervención penal ampara a la conciliación? ¿Cuáles son los fundamentos de necesidad y proporcionalidad para encauzar la conciliación en los delitos de peculado? El método utilizado en la investigación es el histórico lógico, documental, bajo un enfoque cualitativo, los cuales permitieron obtener los principales resultados y cuestionar la posibilidad de aplicar la conciliación en los delitos de peculado.
Employee Education and Training Recommendations using the Apriori Algorithm
Authors: Arief Wibowo  , Vasthu Imaniar Ivanoti  , Megananda Hervita Permata Sari
Published: October 2023

The Ministry of Finance (MoF) aims to enhance employee performance through suitable education and training opportunities. Based on the data on the implementation of education and training in 2022 in the MoF Central ICT Department, only 27.35% of the employees participated in education and training according to the proposed needs for both positions and individuals. This is partly due to mandatory training that must be attended by some or all employees, urgent needs in the current year, or substitute participants who are not from the same team or function. To address this issue, the association method of data mining techniques can be utilized to analyze historical data of employees. The study used the a priori algorithm to analyze historical data on employee positions, organizations, and education and training from 2011 to 2021. This research involved comparing various minimum support values, assuming that employees attended at least 2, 3, and 4 training courses, to calculate the corresponding minimum support values. The evaluation results of the model show that the best rules are generated with a minimum support value of 0.013 and a minimum confidence value of 0.6, which is a total of 10 rules. One of the training recommendations is that if an employee has taken the Enterprise Service Bus (ESB)-API Management training, they will take the ESB API Integration Platform training. Furthermore, it can be used by the Human Resources Unit to provide education and training aligned with organizational needs and improve employee competency in line with their duties and functions, leading to better overall organizational performance.
Developing Cost Effective Smartwatch Heart Rate Monitoring for Android Device
Authors: Muhammad Khalif Fadhilah  , Lulu Chaerani Munggaran
Published: October 2023

Heart related disease is one of deadly non communicable diseases. In order to detect heart related problems, heart rates must be monitored. Monitoring heart rate can be done with several methods, from stethoscope, to sensors such as PPG and ECG sensors. However, those monitoring can be impractical as it requires doctor visitations. In order to simplify the process, smartwatch is used. Those devices are usually equipped with heart rate monitoring sensors, and many others. However, some previously researched smartwatch-based systems used in monitoring health are cost prohibitive as some requires their own server, high price of smartwatches used, and cumbersome to use. The goal of this research is to build cost effective heart rate monitoring using cheap smartwatches. A proposed system using smartwatch and Android device is used alongside with Whatsapp messaging, with ringtone that plays when emergency situation happened. The message contains GPS location and emergency condition. The resulting system does not require custom made server and nets an acceptable GPS coordinate accuracy outdoors, but not so accurate indoors. It also does not require expensive smartwatches. However, the system requires the device to not be locked due to limitations on Android devices.
Taking into account a priori information in the iterative reconstruction of images of foundry products
Authors: Zolotarev S. A. , Taruat A. T. T. , Bilenko E. G.
Published: October 2023

Methods of restoring images and properties of non-destructive testing objects based on solving inverse problems (problems of restoring distribution functions of unknown characteristics of an object based on the results of indirect measurements) are considered. Management methods are based on solving inverse problems and allow you to get the most complete information about the distributed properties of an object. The need to attract additional information imposes serious restrictions on the development of universal applied algorithms for solving incorrectly set tasks. As a rule, individual additional information is available for each specific non-destructive testing task. An effective numerical algorithm for solving an incorrectly posed problem should be focused on taking this information into account at each stage of the solution search. When solving an applied problem, it is also necessary that the algorithm corresponds to both the measuring capabilities and the capabilities of available computing tools. The problem of low-projection X-ray tomography is always associated with a lack of initial data and can only be solved using a priori information. To introduce the necessary additional information into the numerical algorithm, the methods of iterative reconstruction of tomographic images are identified as the most suitable. One of the approaches to the presentation of this kind of information is described. A practical solution to this problem will expand the scope of the X-ray tomography method.
Detection and In Silico Study of Neochlorogenic Acid from Rhizophora apiculata Stem Bark Extract as HBV Replication Inhibitors
Authors: Khalil Muhammad , Dwitya Yonadiah
Published: October 2023

This study aims to detect and characterize the presence of neochlorogenic acid in Rhizophora apiculata stem bark extract and to examine its potential as an inhibitor of Hepatitis B virus (HBV) replication with in silico approach. This explorative descriptive study used liquid chromatography-mass spectrometry (LC-MS/MS) analysis to detect the content of neochlorogenic acid, and an in silico study through molecular docking analysis using the blind docking technique to test its potential to inhibit HBV replication. LCMS/MS results showed that the neochlorogenic acid was present in R. apiculata stem bark extract which was detected with a peak at 3.94 retention time, and fragment ion with a m/z value of 355.1029. The docking analysis results showed that neochlorogenic acid forms a binding site that is relatively similar to the reference ligand to the HBV capsid protein, involving amino acid residues PHE 23, PRO 25, PHE 110, TYR 118, TRP 102, ILE 139, LEU 140, and SER 141, with binding affinity score -6.3 kcal/mol. Therefore, based on the results of this study, it can be concluded that neochlorogenic acid derived from stem bark extract of R. apiculata has the potential to be used as an alternative treatment for hepatitis B virus infection.
PERSPECTIVA ATUAL SOBRE O USO DE TECNOLOGIAS DE INFORMAÇÃO E COMUNICAÇÃO EM PESSOAS COM TRANSTORNO DO ESPECTRO DO AUTISMO
Authors: Oliveira Roseane Lima de
Published: October 2023

O artigo em destaque é consecutivo da dissertação de mestrado que apresenta o seguinte título: A evolução no processo de alfabetização de alunos com TEA em uma Sala de Recursos na cidade de Manaus no ano de 2020. Este estudo segue uma abordagem qualitativa, descritiva e tem como objetivo: Avaliar o impacto das Tecnologias de Informação e Comunicação (TIC) na inclusão, aprendizado e autonomia de alunos com TEA. O problema da pesquisa compreende: Em que medida as TICs têm contribuído para o aprendizado e desenvolvimento acadêmico dos educandos com TEA? O estudo apresentou como resultado a importância do foco na utilização das TICs para desenvolver e melhorar competências educativas do transtorno do espectro do autismo (TEA), uma vez que essas tecnologias estão cada vez mais presentes em nossa sociedade e têm um grande impacto no ensino e aprendizagem. O resultado do estudo apontou que as pessoas com TEA têm uma afinidade natural para trabalhar com as TIC, pois lhes proporciona um ambiente controlado, atenção individualizada e possibilidade de repetição das atividades propostas. Também foi demonstrado que estes tipos de atividades digitais podem motivar e incentivar a aprendizagem destas pessoas. Compreendeu-se, a importância de trabalhar e ampliar o conhecimento sobre o transtorno do espectro do autismo, conhecer diferentes ferramentas, programas e seus benefícios.

Palavras-chave: TEA, Tecnologias de Informação e Comunicação (TIC), Desenvolvimento, Ensino. Aprendizagem.
O VÍNCULO FAMILIAR COMO FATOR DETERMINANTE NO SUCESSO ESCOLAR DOS ALUNOS DO ENSINO FUNDAMENTAL
Authors: Farias Maria Elzineide do Espírito Santo
Published: October 2023

Este artigo decorre da dissertação de mestrado intitulado: Escola e Família: A Influência da Família no Desempenho Escolar do Aluno. Esta pesquisa aborda as questões relacionadas ao desempenho acadêmico e a forma como ele é influenciado pela família. Uma das principais variáveis que acompanham essas transformações é a incorporação da família como reguladora no processo de aprendizagem. Isto torna essencial poder discutir a situação atual da família no âmbito escolar, e poder perceber como isso influencia os aspectos que envolvem a aprendizagem. Assim, o estudo apresenta como objetivo: Analisar a natureza e a qualidade dos vínculos familiares e como esses vínculos influenciam no desempenho acadêmico. Foi desenvolvido um estudo qualitativo, aparado na pesquisa bibliográfica, descritiva. O estudo traz o seguinte questionamento: Qual o vínculo que o contexto familiar tem com o desempenho acadêmico dos alunos? O resultado do estudo apontou que o vínculo estabelecido entre os familiares constitui um ambiente decisivo para o desenvolvimento e configuração da formação do educando; por outro lado, indica que o vínculo familiar têm um impacto positivo no desempenho escolar e que depende também do contexto em que a família e o aluno se desenvolvem, pois é importante a percepção que os jovens têm sobre a avaliação positiva ou negativa que a família faz deles, a percepção deles sobre o apoio que a família lhes proporciona. A percepção dos pais sobre as tarefas, as suas expectativas futuras, a sua comunicação com os alunos e a sua preocupação com eles, mostram também que cresce o vínculo e consequentemente o desempenho acadêmico.
Palavras-chave: Vinculo Familiar. Desempenho. Sucesso. Aprendizagem.
La adaptación sin fin. Versiones de El Pisito (1958) y El Cochecito (1961) escritas por Rafael Azcona
Authors: Deltell Luis , Alfeo Juan Carlos
Published: October 2023

El novelista y guionista español Rafael Azcona presenta un caso interesante en el proceso de reescritura y adaptación con los temas de El pisito y El cochecito. El método de escritura, adaptación y reescritura que propone Azcona resulta insólito, pues, sobre cada uno de estos dos asuntos, el autor publicó diversos cuentos, novelas y los adaptó en sendos guiones. Las películas de El pisito (Marco Ferreri e Isidoro M. Ferry, 1958) y El cochecito (Marco Ferreri, 1960) reflejan solo una pequeña parte de esta vasta creación en torno a dichos asuntos. Nuestra investigación ha indagado en todos los artículos, cuentos y textos escritos por Azcona acerca de estos temas. Para ello se ha consultado fuentes primarias, como el archivo de la censura literaria y cinematográfica (Archivo General de la Administración), fondo inédito de la Filmoteca Española y Biblioteca Nacional; y, además, se ha consultado las publicaciones científicas sobre el autor. El resultado ha sido la recuperación de un texto inédito y desconocido hasta la fecha, Concierto para pobre, paralítico y muerto, y ha permitido indagar en este proceso de reescritura y adaptación sobre El pisito y El cochecito. Se trata, concluimos en la investigación, de un ejemplo único en el que un autor español no solo adapta y noveliza repetidamente, sino que, además, reescribe completamente sus obras, pudiendo hablar de tres textos completamente distintos para ambos casos.
Funciones de los emojis en las representaciones de personas LGBTIQ+: análisis de comentarios de Facebook
Authors: Alarcón Paola , Urrutia Martínez Mabel , Venegas Carrasco Carolina , Díaz Larenas Claudio
Published: October 2023

En este trabajo, sostenemos que las representaciones sociales se construyen discursivamente y que, junto con los recursos verbales, es necesario relevar el rol de otros modos semióticos. En consecuencia, el objetivo del estudio es analizar las funciones que desempeñan los emojis en las representaciones discursivas de personas LGBTIQ+, en comentarios a noticias expuestas por medios de comunicación chilenos en Facebook, entre 2019 y 2021. En el marco teórico se revisan las descripciones de estos recursos desde el punto de vista pragmático, así como su relación con las emociones. La investigación se enmarca en el paradigma interpretativo, utilizando un enfoque cualitativo de análisis de corpus. Para la recolección y el análisis de datos se utilizan los métodos de la Teoría Fundamentada Empíricamente, específicamente, la comparación constante, el muestreo teórico y las diferentes estrategias de codificación. El análisis muestra que los emojis se usan para expresar actitudes a favor y en contra de las personas LGBTIQ+ mediante: a) la simulación de emociones y b) la representación de las personas LGBTIQ+.
La negociación de posturas (inter)subjetivas autorales en entrevistas ciudadanas sobre las elecciones presidenciales costarricenses 2018
Authors: Arroyo-Mata Marco A. , Cruz Volio Gabriela , Vergara Heidke Adrián
Published: October 2023

La negociación de posturas (inter)subjetivas autorales en entrevistas ciudadanas sobre las elecciones presidenciales costarricenses 2018 explora el rol de las modalidades lingüísticas en la construcción de posturas evaluativas. Estudios previos han sugerido que estas contribuyen en la creación de contextos discursivos dinámicos y su estudio permite entender fenómenos sociales. Con esto en mente, se realizaron entrevistas sobre el proceso electoral 2018 a ciudadanos costarricenses —incluyendo a hombres y mujeres de diferentes zonas geográficas, edades, niveles educativos y afiliaciones políticas— para, posteriormente, identificar sus posturas autorales y analizarlas mediante nuevas categorías lingüísticas basadas en los estudios diacrónicos gramaticales de Narrog (2017). De acuerdo con los resultados, los participantes construyeron posturas principalmente subjetivas con marcadores modales epistémicos, por lo que hubo una mayor inclinación por compartir sus opiniones desde una perspectiva personal que por negociarlas con terceros. Se concluye que las modalidades (inter)subjetivas cumplen un rol dinámico en esta situación comunicativa y se estructuran según las metas locutivas del hablante.
Antígona de José Watanabe: reescritura y memoria en la poesía sobre la violencia política peruana
Authors: Chueca Luis
Published: October 2023

El artículo estudia la reescritura poética realizada por José Watanabe de Antígona de Sófocles, enfatizando dos dimensiones: las operaciones de absorción y transformación que conducen al texto final, y la particular lectura de esta Antígona desde el contexto de su publicación. En diálogo con conceptos como reescritura y dialogismo (Bajtín), memoria (Jelin) y violencia (Žižek), el análisis constata que los nuevos sentidos que esta Antígona incorpora plantean preguntas y demandas fundamentales en relación con el proceso de violencia y dictadura que se vivía en el Perú, así como con las razones históricas que contribuyeron a su desencadenamiento. A partir de esto, Antígona relieva implícitamente la necesidad de intervenir, desde la poesía y el arte, en la vida del país, e inicia, simbólicamente, una nueva etapa en el desarrollo de la poesía sobre el conflicto armado interno.
PLACERES DEL PODER EN VALPORNO DE NATALIA BERBELAGUA
Authors: Candia-Cáceres Alexis , Rosales Neira Oscar
Published: October 2023

En este artículo, analizamos la función y representación del erotismo en Valporno de Natalia Berbelagua. Proponemos interpretar la colección de relatos a partir de dos conceptos claves para comprender el alcance del fenómeno erótico en el texto: “Asimetría del poder” y “Ritualización de lo abyecto”. Para ello, realizamos un análisis basado en diversos recursos de la teoría literaria, la filosofía y la psicología.