bluuebunny/crossref_metadata_2025 huggingface dataset:
Single Ventricle and Total Anomalous Pulmonary Venous Connection: Implications of Prenatal Diagnosis
Authors: Hancock Hayley S. , Romano Jennifer C. , Armstrong Aimee , Yu Sunkyung , Lowery Ray , Gelehrter Sarah
Published: June 2018

Background:

Single ventricle (SV) patients with total anomalous pulmonary venous connection (TAPVC) are at high risk. Given the limited published data available, we examined outcomes and the implications of a prenatal diagnosis of SV/TAPVC.

Methods:

A single-center, retrospective review was performed in neonates with SV/TAPVC from 1998 to 2014, identified through institutional databases. Patient demographic, perioperative, and follow-up data were collected.

Results:

Thirty-four eligible infants with SV/TAPVC were identified (mean birth weight: 3.0 kg). The TAPVC types were supracardiac (59%), infracardiac (21%), mixed (12%), and cardiac (9%). Heterotaxy syndrome was present in 25 (74%) infants. A prenatal diagnosis of SV was made in 26 (76%) infants, with TAPVC identified in 12 (35%). Seventeen (50%) had obstructed TAPVC within the first 48 hours of life; 7 of these patients had obstructed TAPVC identified prenatally. There were two preoperative deaths. Overall survival for the cohort was 65% at 1 year and 50% at 3 years. Survival in the obstructed group was significantly worse compared to the unobstructed group (47% vs 81% at 1 year; 27% vs 73% at 3 years, P = .01). Obstructed TAPVC and a prenatal prediction of obstructed TAPVC were significantly associated with postoperative mortality ( P = .01 and .03, respectively).

Conclusions:

Patients with SV/TAPVC remain a high-risk group, with obstructed TAPVC a significant risk factor for mortality. Prenatal diagnosis of TAPVC in SV patients is challenging, but given those with obstructed TAPVC are especially at high risk, improved prenatal diagnostic techniques in this group may enhance counseling/delivery planning.
History of the World Society for Pediatric and Congenital Heart Surgery: The First Decade
Authors: Jacobs Jeffrey P. , Tchervenkov Christo I. , Stellin Giovanni , Kurosawa Hiromi , Mavroudis Constantine , Jatene Marcelo B. , Al-Halees Zohair , Cicek Sertac M. , Sandoval Nestor F. , Backer Carl L. , Cervantes Jorge , Dearani Joseph A. , Ebels Tjark , Edwin Frank , Finucane Kirsten , Fragata Jose , Iyer Krishna S. , Kinsley Robin H. , Kirklin James K. , Kreutzer Christian , Liu Jinfen , Maruszewski Bohdan , St. Louis James D. , Sarris George E. , Jonas Richard A.
Published: June 2018

The World Society for Pediatric and Congenital Heart Surgery (WSPCHS) is the largest professional organization in the world dedicated to pediatric and congenital heart surgery. The purpose of this article is to document the first decade of the history of WSPCHS from its formation in 2006, to summarize the current status of WSPCHS, and to consider the future of WSPCHS. The WSPCHS was incorporated in Canada on April 7, 2011, with a head office in Montreal, Canada. The vision of the WSPCHS is that every child born anywhere in the world with a congenital heart defect should have access to appropriate medical and surgical care. The mission of the WSPCHS is to promote the highest quality comprehensive cardiac care to all patients with congenital heart disease, from the fetus to the adult, regardless of the patient’s economic means, with an emphasis on excellence in teaching, research, and community service.
School Counselors and College Readiness Counseling
Authors: Gilfillan Beth H.
Published: June 2018

School counselors are vital to helping students become college ready. Professional organizations (i.e., American School Counselor Association, Council for Accreditation of Counseling and Related Programs, and National Association for College Admission Counseling) highlight the need for school counselors to provide college readiness counseling, yet the particular skills and knowledge needed to provide it have not been comprehensively explored. This conceptual article with practical applications identifies student needs, responsibilities of school counselors, training of school counselors, and advocacy issues as essential elements to develop college readiness counseling.
Reablement in Mental Health Care and the Role of the Occupational Therapist: A Qualitative Study
Authors: Seberg Merethe , Eriksson Bengt G.
Published: June 2018

So far, reablement is mainly developed in care for the elderly. This study adds knowledge about reablement in mental health care and the contribution of occupational therapists to this field. Qualitative interviews with 10 occupational therapists were conducted and analyzed using a qualitative content analysis. Reablement is built around everyday activities, used as systematic tools for stepwise improvement of mastery and bettered mental health. The findings support a greater emphasis on reablement and recovery in mental health care. Reablement demands multidisciplinary teams, where occupational therapists can bring important skills and perspectives. Occupational therapists can contribute substantially to further reablement. Their knowledge about—and therapeutic use of—everyday life activities seem to be a useful approach to helping people with mental illness. The occupational therapy foundations are highly related to the elements of recovery.
Promoting Personal Growth and Balancing Risk of Violence in Community-Based Mental Health Care: A Professional Perspective
Authors: Gamme Mari , Eriksson Bengt G.
Published: June 2018

The aim of this study was to investigate how municipal mental health care workers develop professional strategies, taking the risk of service user violence into account. Factors that professionals regard as hindering or furthering personal growth among the service users are particularly focused. Data were collected through focus group interviews. The analysis resulted in two main categories: working where the clients live their lives and focus on growth and development. Offering opportunities for restraint and growth for people with serious mental health disorders and risk of violence represents the basic factors for improving desirable processes. The health-promoting focus was managed through a resource-oriented and growth-oriented focus, where available services and workers’ qualities and attitudes appear to be crucial.
Infants’ Visual Preferences for Prosocial Behavior and Other-Race Characters at 6 Months: An Eye-Tracking Study
Authors: Holvoet Claire , Arciszewski Thomas , Scola Céline , Picard Delphine
Published: June 2018

There is growing evidence that infants display preferences for prosocial agents. However, recent studies have reported conflicting results about the impact of appearance on these preferences. The current study investigated the relative influence of behavior and face/race on 6-month-old infants’ evaluation of social agents when these two aspects are in competition. In a short research study featuring animated cartoons where agents interacted in a ball game, we used eye-tracking methodology to assess infants’ preferences (a) for prosocial behavior, (b) for one kind of appearance, represented by race, and (c) when the two aspects were pitted against one another. The two control conditions revealed preferences for prosocial agents and for other-race appearance. No preference could be found at group level in the third condition, where these two aspects competed with each other. However, a profile analysis revealed that when this situation was a source of conflict in terms of the preferences identified in the control conditions, infants prioritized appearance over behavior.
Factors Influencing Academic Motivation of Ethnic Minority Students: A Review
Authors: Isik Ulviye , Tahir Omaima El , Meeter Martijn , Heymans Martijn W. , Jansma Elise P. , Croiset Gerda , Kusurkar Rashmi A.
Published: June 2018

The aim of this study to create a comprehensive overview of factors that may influence motivation of ethnic minority students from their own perspective. A systematic review was conducted in PubMed, ERIC, and PsycINFO to find studies in which the motivation of ethnic minority students was studied. The articles reviewed were qualitatively synthesized by means of meta-ethnography, and were subjected to a quantitative meta-analysis where appropriate. Forty-five articles were included. Several factors were found to have either a positive or a negative influence on academic motivation, which can be classified into individual, family-related, school-related, and social factors. These factors should be taken into account when developing interventions aimed at enhancing motivation, which is expected to improve. However, evidence for the influence of most identified factors is weak, given that almost every factor was investigated in a single study only. Based on the outcomes of the current overview an integrative model, that provides a structure of the identified factors in relation to motivation which can be used for interventions, cannot be generated; thus, further research is needed.
Differences in Postoperative Changes of Cervical Sagittal Alignment and Balance After Laminoplasty Between Cervical Spondylotic Myelopathy and Cervical Ossification of the Posterior Longitudinal Ligament
Authors: Sakaura Hironobu , Ohnishi Atsunori , Yamagishi Akira , Ohwada Tetsuo
Published: June 2018

Study Design:

Retrospective cohort study.

Objectives:

To compare postoperative changes of cervical sagittal alignment (CSA) and cervical sagittal balance (CSB) after laminoplasty between cervical spondylotic myelopathy (CSM) and ossification of the posterior longitudinal ligament (OPLL) and to examine impacts of these radiologic changes on neurologic outcomes.

Methods:

A total of 168 consecutive patients with CSM (CSM group) and 51 consecutive patients with OPLL (OPLL group) were included. As indicators of CSA and CSB, the C2-7 angle and C1-C7 sagittal vertical axis (SVA) were, respectively, measured before surgery and at 2-year follow-up. Neurologic status was assessed using the Japanese Orthopaedic Association score before surgery and at 2-year follow-up.

Results:

Whereas both postoperative loss of C2-7 angle and increase of C1-C7 SVA were significantly greater in the elderly subgroup of the CSM group, patient age did not significantly affect these changes in the OPLL group. Preservation of C7 maintained C1-C7 SVA at postoperative 2 years only in the CSM group. Postoperative cervical kyphosis and sagittal imbalance significantly decreased neurologic improvement in the CSM group but not in the OPLL group.

Conclusions:

Elderly patients with CSM have significantly greater postoperative loss of lordosis and increase in C1-C7 SVA than nonelderly patients, and both postoperative kyphotic deformity and sagittal imbalance significantly deteriorate neurologic recovery. On the other hand, although patients with OPLL, irrespective of patient age and preservation of C7, have significantly more loss of lordosis and increase in C1-C7 SVA than CSM patients, neither postoperative kyphotic deformity nor sagittal imbalance significantly deteriorates neurologic recovery in OPLL patients.
Propagation of Syndesmotic Injuries During Forced External Rotation in Flexed Cadaveric Ankles
Authors: Mait Alexander Ritz , Forman Jason Lee , Nie Bingbing , Donlon John Paul , Mane Adwait , Forghani Ali Reza , Anderson Robert B. , Cooper M. Truitt , Kent Richard W.
Published: June 2018

Background:

Forced external rotation of the foot is a mechanism of ankle injuries. Clinical observations include combinations of ligament and osseous injuries, with unclear links between causation and injury patterns. By observing the propagation sequence of ankle injuries during controlled experiments, insight necessary to understand risk factors and potential mitigation measures may be gained.

Hypothesis:

Ankle flexion will alter the propagation sequence of ankle injuries during forced external rotation of the foot.

Study Design:

Controlled laboratory study.

Methods:

Matched-pair lower limbs from 9 male cadaveric specimens (mean age, 47.0 ± 11.3 years; mean height, 178.1 ± 5.9 cm; mean weight, 94.4 ± 30.9 kg) were disarticulated at the knee. Specimens were mounted in a test device with the proximal tibia fixed, the fibula unconstrained, and foot translation permitted. After adjusting the initial ankle position (neutral, n = 9; dorsiflexed, n = 4; plantar flexed, n = 4) and applying a compressive preload to the tibia, external rotation was applied by rotating the tibia internally while either lubricated anteromedial and posterolateral plates or calcaneal fixation constrained foot rotation. The timing of osteoligamentous injuries was determined from acoustic sensors, strain gauges, force/moment readings, and 3-dimensional bony kinematics. Posttest necropsies were performed to document injury patterns.

Results:

A syndesmotic injury was observed in 5 of 9 (56%) specimens tested in a neutral initial posture, in 100% of the dorsiflexed specimens, and in none of the plantar flexed specimens. Superficial deltoid injuries were observed in all test modes.

Conclusion:

Plantar flexion decreased and dorsiflexion increased the incidence of syndesmotic injuries compared with neutral matched-pair ankles. Injury propagation was not identical in all ankles that sustained a syndesmotic injury, but a characteristic sequence initiated with injuries to the medial ligaments, particularly the superficial deltoid, followed by the propagation of injuries to either the syndesmotic or lateral ligaments (depending on ankle flexion), and finally to the interosseous membrane or the fibula.

Clinical Relevance:

Superficial deltoid injuries may occur in any case of hyper–external rotation of the foot. A syndesmotic ankle injury is often concomitant with a superficial deltoid injury; however, based on the research detailed herein, a deep deltoid injury is then concomitant with a syndesmotic injury or offloads the syndesmosis altogether. A syndesmotic ankle injury more often occurs when external rotation is applied to a neutral or dorsiflexed ankle. Plantar flexion may shift the injury to other ankle ligaments, specifically lateral ligaments.
Traditional Practices and Beliefs in Post-partum Care: Tribal Women in Maharashtra
Authors: Dehury Ranjit Kumar , Pati Ashalata , Dehury Parthsarathi
Published: June 2018

Post-natal care and traditional post-partum practices have important bearings in maternal and child health outcomes. A study was conducted to understand the traditional post-partum practices by the tribal mothers in rural areas of Vikramgad taluka, Maharashtra, India. A qualitative methodology has been adopted by using data collection methods like focus group discussions (FGDs) and in-depth interviews. Key informant interview methods were adopted to understand the mother’s post-natal diet, personal hygiene, physical activity and rest, neonatal feeding and care practices during pregnancy. Respondents reported that the mother in the post-partum period, locally called balantini , has to follow certain specific practices regarding diet, hygiene and rest to keep herself and her baby healthy. The study reflects on how traditional beliefs and practices affirm gender biases, traditional beliefs and practices when it comes to new mothers and their care. To address the health needs of these ‘last women’, the government and civil society have to work for the reduction of poverty, removal of harmful practices, gender equity and empowerment.
An Eco-Feminist Water Revival Project in Gujarat
Authors: Chakraborty Meghadeepa
Published: June 2018

This article brings forth the strength of women in the revival, restoration and protection of the environment through collective efforts and initiatives. A small village of Gujarat is the case study. A group of women took the leadership and worked day and night to resolve the issue of water crisis in their village and trained themselves as barefoot geologists and revived the traditional water reservoir. The availability and accessibility of sufficient water has changed the entire struggle chain of the community and brought new life in the way of development.
Analysis of pulmonary features and treatment approaches in the COPA syndrome
Authors: Tsui Jessica L. , Estrada Oscar A. , Deng Zimu , Wang Kristin M. , Law Christopher S. , Elicker Brett M. , Jones Kirk D. , Dell Sharon D. , Gudmundsson Gunnar , Hansdottir Sif , Helfgott Simon M. , Volpi Stefano , Gattorno Marco , Waterfield Michael R. , Chan Alice Y. , Chung Sharon A. , Ley Brett , Shum Anthony K.
Published: June 2018

The COPA syndrome is a monogenic, autoimmune lung and joint disorder first identified in 2015. This study sought to define the main pulmonary features of the COPA syndrome in an international cohort of patients, analyse patient responses to treatment and highlight when genetic testing should be considered.

We established a cohort of subjects (N=14) with COPA syndrome seen at multiple centres including the University of California, San Francisco, CA, USA. All subjects had one of the previously established mutations in theCOPAgene, and had clinically apparent lung disease and arthritis. We analysed cohort characteristics using descriptive statistics.

All subjects manifested symptoms before the age of 12 years, had a family history of disease, and developed diffuse parenchymal lung disease and arthritis. 50% had diffuse alveolar haemorrhage. The most common pulmonary findings included cysts on chest computed tomography and evidence of follicular bronchiolitis on lung biopsy. All subjects were positive for anti-neutrophil cytoplasmic antibody, anti-nuclear antibody or both and 71% of subjects had rheumatoid factor positivity. All subjects received immunosuppressive therapy.

COPA syndrome is an autoimmune disorder defined by diffuse parenchymal lung disease and arthritis. We analysed an international cohort of subjects with genetically confirmed COPA syndrome and found that common pulmonary features included cysts, follicular bronchiolitis and diffuse alveolar haemorrhage. Common extrapulmonary features included early age of onset, family history of disease, autoantibody positivity and arthritis. Longitudinal data demonstrated improvement on chest radiology but an overall decline in pulmonary function despite chronic treatment.
Significant concordance of genetic variation that increases both the risk for obsessive–compulsive disorder and the volumes of the nucleus accumbens and putamen
Authors: Hibar Derrek P. , Cheung Joshua W. , Medland Sarah E. , Mufford Mary S. , Jahanshad Neda , Dalvie Shareefa , Ramesar Raj , Stewart Evelyn , van den Heuvel Odile A. , Pauls David L. , Knowles James A. , Stein Dan J. , Thompson Paul M. ,   Enhancing Neuro Imaging Genetics through Meta Analysis (ENIGMA) Consortium and International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC)
Published: June 2018

Background

Many studies have identified changes in the brain associated with obsessive–compulsive disorder (OCD), but few have examined the relationship between genetic determinants of OCD and brain variation.

Aims

We present the first genome-wide investigation of overlapping genetic risk for OCD and genetic influences on subcortical brain structures.

Method

Using single nucleotide polymorphism effect concordance analysis, we measured genetic overlap between the first genome-wide association study (GWAS) of OCD (1465 participants with OCD, 5557 controls) and recent GWASs of eight subcortical brain volumes (13 171 participants).

Results

We found evidence of significant positive concordance between OCD risk variants and variants associated with greater nucleus accumbens and putamen volumes. When conditioning OCD risk variants on brain volume, variants influencing putamen, amygdala and thalamus volumes were associated with risk for OCD.

Conclusions

These results are consistent with current OCD neurocircuitry models. Further evidence will clarify the relationship between putamen volume and OCD risk, and the roles of the detected variants in this disorder.

Declaration of interest

The authors have declared that no competing interests exist.
Leptin Regulation of Cancer Stem Cells in Breast and Gynecologic Cancer
Authors: Crean-Tate Katie K , Reizes Ofer
Published: June 2018

It is well established that obesity increases the incidence and worsens the prognosis of women’s cancer. For breast cancer, women with obesity exhibit more than a twofold increase in the odds of being diagnosed with cancer, with a greater risk of advanced stage at diagnosis, and ≤40% greater risk of recurrence and death than their normal-weight counterparts. These findings are similar in gynecologic cancers, where women who are obese with a body mass index (BMI) >40 kg/m2 have up to six times greater risk of developing endometrial cancer and a 9.2% increase in mortality with every 10% increase in BMI. Likewise, patients with obesity exhibit a twofold higher risk of premenopausal ovarian cancer, and patients who are obese with advanced stage ovarian cancer have shown a shorter time to recurrence and poorer overall survival. Obesity is accompanied by changes in expression of adipose factors that act on local tissues and systemically. Once obesity was recognized as a factor in cancer incidence and progression, the adipose cytokine (adipokine) leptin became the focus of intense investigation as a putative link, with nearly 3000 publications on the topic. Leptin has been shown to increase cell proliferation, inhibit apoptosis, promote angiogenesis, and increase therapeutic resistance. These characteristics are associated with a subset of cells in both liquid and solid tumors known as cancer stem cells (CSCs), or tumor initiating cells. We will review the literature discussing leptin’s role in breast and gynecologic cancer, focusing on its role in CSCs, and consider goals for targeting future therapy in this arena to disrupt tumor initiation and progression in women’s cancer.
AMP-activated protein kinase promotes epithelial-mesenchymal transition in cancer cells through Twist1 upregulation
Authors: Saxena Meera , Balaji Sai A. , Deshpande Neha , Ranganathan Santhalakshmi , Pillai Divya Mohan , Hindupur Sravanth Kumar , Rangarajan Annapoorni
Published: June 2018

The developmental programme of epithelial-mesenchymal transition (EMT), involving loss of epithelial and acquisition of mesenchymal properties, plays an important role in the invasion-metastasis cascade of cancer cells. In the present study, we show that activation of AMP-activated protein kinase (AMPK) using A769662 led to a concomitant induction of EMT in multiple cancer cell types, as observed by enhanced expression of mesenchymal markers, decrease in epithelial markers, and increase in migration and invasion. In contrast, inhibition or depletion of AMPK led to a reversal of EMT. Importantly, AMPK activity was found to be necessary for the induction of EMT by physiological cues such as hypoxia and TGFβ treatment. Furthermore, AMPK activation increased the expression and nuclear localization of Twist1, an EMT transcription factor. Depletion of Twist1 impaired AMPK-induced EMT phenotypes, suggesting that AMPK might mediate its effects on EMT, at least in part, through Twist1 upregulation. Inhibition or depletion of AMPK also attenuated metastasis. Thus, our data underscore a central role for AMPK in the induction of EMT and in metastasis, suggesting that strategies targeting AMPK might provide novel approaches to curb cancer spread.
Fluid shift vs. body size: changes of hematological parameters and body fluid volumes in hindlimb-unloaded mice, rats and rabbits
Authors: Andreev-Andrievskiy Alexander A. , Popova Anfisa S. , Lagereva Evgeniia A. , Vinogradova Olga L.
Published: June 2018

Cardiovascular system is adapted to gravity, and reactions to its vanishing in space are presumably dependent on body size. Dependency of hematological parameters and body fluids reaction to simulated microgravity have never been studied as an allometric function before. Thus we estimated RBC, blood and extracellular fluid volumes in hindlimb-unloaded (HLU) or control (ATT) mice, rats and rabbits.

RBC decrease was found to be size-independent, and the allometric dependency for red blood loss in HLU and ATT animals shared a common power (−0.054±0.008) but differrent Y0 (8.66±0.40 and 10.73±0.49 correspondingly, p<0.05). Blood volume in HLU animals was unchanged compared to controls disregarding the body size. The allometric dependencies for interstitial fluid volume in HLU and ATT mice shared Y0 (1.02±0.09) but had different powers N (0.708±0.017 and 0.648±0.016 correspondingly, p<0.05), indicating that interstitial fluid volume increase during hindlimb unloading is more pronounced in larger animals.

Our data underscore the importance of size-independent mechanisms of cardiovascular adaptation to weightlessness. Despite use of mice hampers application of a straightforward translational approach, this species is useful for gravitational biology as a tool to investigate size-independent mechanisms of mammalian adaptation to microgravity.
ΑΙ ΜΑΣΤΙΤΙΔΕΣ ΤΩΝ ΑΓΕΛΑΔΩΝ ΚΑΙ Η ΑΠΟ ΑΠΟΨΕΩΣ ΔΗΜΟΣΙΑΣ ΥΓΕΙΑΣ ΣΗΜΑΣΙΑ AYTΩN
Authors: ΤΑΡΛΑΖΗΣ Κ. , ΧΡΙΣΤΟΔΟΥΛΟΥ Θ.
Published: June 2018

NO ABSTRACT AVAILABLE
ΠΕΡΙ ΤΩΝ EN ΤΑΙΣ ΙΠΠΟΔΡΟΜΙΑΙΣ ΧΡΗΣΙΜΟΠΟΙΟΥΜΕΝΩΝ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΟΥΣΙΩΝ (ΝΤΟΠΙΝ) ΩΣ ΔΙΕΓΕΡΤΙΚΩΝ ΜΕΣΩΝ
Authors: ΚΙΝΝΑΣ ΚΩΝΣΤΑΝΤΙΝΟΣ Σ.
Published: June 2018

NO ABSTRACT AVAILABLE
Η ΛΙΣΤΕΡΙΑΣΙΣ ΤΟΥ ΠΡΟΒΑΤΟΥ ΕΝ ΕΛΛΑΔΙ
Authors: ΤΑΡΛΑΤΖΗΣ ΧΡΙΣΤΟΔΟΥΛΟΣ
Published: June 2018

NO ABSTRACT AVAILABLE
H ΠΡΟΝΥΜΦΙΚΗ ΠΕΝΤΑΣΤΟΜΩΣΙΣ ΩΣ ΠΡΟΔΙΑΘΕΤΟΝ ΑΙΤΙΟΝ ΤΗΣ ΕΝΤΕΡΟΤΟΞΙΝΑΙΜΙΑΣ TΩN ΠΡΟΒΑΤΩΝ
Authors: ΤΡΙΑΝΤΟΠΟΥΛΟΣ ΕΛΕΥΘΕΡΙΟΣ
Published: June 2018

NO ABSTRACT AVAILABLE
Al ΠΡΟΟΔΟΙ ΕΙΣ ΤΗΝ ΚΤΗΝΙΑΤΡΙΚΗΝ
Authors: OGILVIE D. D.
Published: June 2018

NO ABSTRACT AVAILABLE
ΔΥΟ ΠΕΡΙΠΤΩΣΕΙΣ ΠΕΡΙΕΣΦΙΓΜΕΝΗΣ ΜΕΣΕΝΤΕΡΙΟΚΗΛΗΣ ΕΠΙ ΟΡΝΙΘΩΝ
Authors: ΠΑΝΕΤΣΟΣ Α. , ΔΡΑΓΩΝΑΣ Π.
Published: June 2018

NO ABSTRACT AVAILABLE
Η ΟΞΕΙΑ ΤΟΞΙΚΗ ΕΓΚΕΦΑΛΟΠΑΘΕΙΑ ΤΩΝ ΙΠΠΩΝ (CORNSTALK DISEASE) ΤΑ ΠΡΩΤΑ ΚΡΟΥΣΜΑΤΑ ΕΝ ΕΛΛΑΔΙ
Authors: ΤΑΡΛΑΤΖΗΣ Κ. , ΣΠΑΗΣ Α. , ΧΑΡΙΣΙΑΔΗΣ Ν.
Published: June 2018

NO ABSTRACT AVAILABLE
Η ΛΕΠΤΟΣΠΕΙΡΩΣΙΣ ΤΩΝ ΒΟΟΕΙΔΩΝ
Authors: Van der HOEDEN J.
Published: June 2018

NO ABSTRACT AVAILABLE
Here’s an Opportunity: Knowledge Sharing Among Competitors as a Response to Buy-in Uncertainty
Authors: Botelho Tristan L.
Published: June 2018

Although knowledge sharing among competitors is seemingly counterintuitive, scholars have found that competitors share knowledge under certain conditions: among actors who have a preexisting relationship and who expect direct reciprocity. However, there are examples of knowledge sharing among competitors that cannot fully be explained using these relational mechanisms. In this study, I propose that in markets where competitors are a set of key stakeholders, knowledge sharing is a strategic response to high levels of buy-in uncertainty related to a potential opportunity, namely, the likelihood that stakeholders will come to realize the value of a potential opportunity in a timely fashion. Using a unique data set of knowledge sharing among investment professionals on a digital platform, this study leverages variation in the platform’s knowledge-sharing structure to test this theory. I find that knowledge sharing among these competitors is most likely when buy-in uncertainty for a given opportunity is high and that this knowledge sharing does lead to subsequent buy-in.
Container Dispatching and Conflict-Free Yard Crane Routing in an Automated Container Terminal
Authors: Nossack Jenny , Briskorn Dirk , Pesch Erwin
Published: June 2018

In this research, we focus on a container dispatching and conflict-free yard crane routing problem that arises at a storage yard in an automated, maritime container terminal. A storage yard serves as an intermediate buffer for import/export containers and exchanges containers between the waterside and landside of a maritime terminal. The considered storage yard is perpendicular to the waterside and employs two rail-mounted gantry cranes that have different sizes and thus have the possibility to cross each other. The problem at hand evaluates in which order and by which crane the import/export containers should be transported to minimize the makespan and prevent crane interferences. We solve this problem to optimality by a branch-and-cut approach that decomposes the problem into two problem classes and connects them via logic-based Benders constraints. We assess the quality of our solution method in a computational study.
We've explored… aliens
Authors: Rawstrone Annette
Published: June 2018

How one setting used children's interest in aliens and space to introduce them to STEM subjects. By Annette Rawstrone
Physico-chemical, Antioxidant and Antimicrobial Investigation on New Mixed Ligand Complexes Containing bis(2,4,4-trimethylpentyl)dithiophosphinic acid and 2,2′-bipyridine
Authors: Kumar Pal Tarun , Alam Md. Ashraful , Paul Subrata , Sheikh Md. Chanmiya , Ahmad Hasan
Published: June 2018

New six mixed ligand complexes have been synthesized from bis(2,4,4-trimethylpentyl)dithiophosphinic acid (C16H35PS2) and 2,2′-bipyridine (C10H8N2) with various metal(II) ions. The molecular formula of the mixed ligand complexes were [Mn(C16H34PS2)(C10H8N2)]Cl (1), [Fe(C16H34PS2)(C10H8N2)]Cl (2), [Co(C16H34PS2)(C10H8N2)]Cl (3, [Cu(C16H34PS2)(C10H8N2)]Cl (4), [Zn(C16H34PS2)(C10H8N2)]Cl (5) and [Cd(C16H34PS2)(C10H8N2)]Cl (6). These mixed ligand complexes have been characterized by various physico-chemical techniques such as melting point, molar conductance, magnetic susceptibility measurements as well as UV-VIS, FT-IR, TG and mass spectroscopic analyses. The surface morphology of ligand (2,2′-bipyridine) and synthesized mixed ligand complexes were determined by scanning electron microscope (SEM). The magnetic moment value, color as well as spectral measurements have been suggested that the geometry of the mixed ligand complexes was tetrahedral. The spectral data has been showed that bis(2,4,4-trimethylpentyl)dithiophosphinic acid and 2,2′-bipyridine ligands were acted as uninegative and neutral bidentate ligand, respectively. The complex 5 was found to have better scavenging activity against 2,2-diphenyl-1-picrylhydrazyl. The complex 3 was showed very good antibacterial activity against Clostridium botulinum as compared to standard drug, imipenem. Moreover, the complex 5 also displayed good antifungal activity against Aspergillus niger.
Gypsum Bedding Impact on Hydrogen Sulfide Release from Dairy Manure Storages
Authors: Hile Michael L. , Fabian-Wheeler Eileen E. , Murphy Dennis J. , Meinen Robert J. , Hill Davis E. , Elliott Herschel A. , Bryant Ray B.
Published: June 2018

Abstract.

Elevated hydrogen sulfide (H2S) levels have been observed from open-air dairy manure storages that contain gypsum bedding. Gypsum (calcium sulfate), recycled from construction waste and manufacturing defects, provides a cost-effective bedding alternative for dairy cows. Gypsum bedding is reported to control moisture and bacteria in the stalls and can improve soil structure when land-applied. However, gypsum increases H2S production in the anaerobic environment of deep manure storages, which is released in dangerous concentrations when the manure is agitated. This study was undertaken to quantify and compare the H2S concentrations during agitation of manure storages for three dairy stall management categories: farms that use (1) traditional organic bedding, (2) gypsum bedding, and (3) gypsum bedding followed by a treatment added to the manure storage thought to reduce H2S emissions. Three farms used Vital Breakdown (manufactured by Homestead Nutrition, New Holland, Pa.), and one farm used OK-1000 (Pro Ag Solutions, Hawkins, Tex.). Nineteen agitation events at ten farms were monitored during spring and fall hauling seasons. Portable monitoring instruments recorded H2S concentrations around the perimeter of the manure storages prior to and during agitation. Results show that manure storage agitation at farms that use gypsum bedding produced H2S concentrations that were considered immediately dangerous to life and health (above 100 ppm). Increasing gypsum bedding use significantly increased cumulative H2S concentrations (p < 0.0001). Farms that used Vital Breakdown as an amendment significantly reduced cumulative H2S concentrations when compared to farms not using a manure treatment (p < 0.0001). Lower cumulative H2S concentrations at one farm were attributed to the OK-1000 manure treatment. Keywords: Cow, Dairy, Gas, Gypsum, Hydrogen sulfide, Manure, Safety.
Caminhos Sinuosos: Os Deslizes nos Estudos em Administração Pública e de Empresas
Authors: Cruz Breno de Paula Andrade , Ross Steven Dutt
Published: June 2018

Este ensaio discute 13 deslizes comuns encontrados em estudos no campo de Administração Pública e de Empresas no Brasil, agregando-os em três dimensões. A primeira dimensão, ‘Deslizes por Falta de Reflexão’ inclui deslizes por falta de reflexão dos autores, como, por exemplo, usar a palavra Metodologia na seção que discute Método ou autores economizarem em palavras para apresentar a relevância do trabalho. Já na segunda dimensão, ‘Deslizes na Utilização do Método’, discutimos aspectos referentes ao Método em um trabalho científico, deixando claro, por exemplo, alguns erros cometidos, tais como nomear um Método (Netnografia) e na prática usar outro (Observação Não-Participante). A terceira dimensão ‘Deslizes        no Sentido de Fazer Ciência’, apresenta os deslizes relacionados à relevância de um texto ao se fazer Ciência. Por exemplo, um texto que não apresenta implicações gerenciais e teóricas no campo da Administração Pública e de Empresas ou que não discute questões para futuras pesquisas deixa a desejar no sentido de ser relevante para a Ciência e para as organizações.
O Uso da Triangulação em Teses e Dissertações de Programas de Pós-Graduação em Administração no Brasil
Authors: Cárdenas Alfredo Ribeiro , Da Costa Tiago , Alperstedt Graziela Dias , Feuerschütte Simone Ghisi
Published: June 2018

O uso da triangulação em estudos qualitativos na área da Administração tem sido visto como um procedimento relacionado ao rigor metodológico e incremento da qualidade de pesquisas, incluindo teses e dissertações. Não obstante, devido às diversas possibilidades de empregá-la, a concepção e prática da triangulação aparentam ainda não estar completamente compreendidas. Neste sentido, este estudo teve como objetivo identificar, analisar e exemplificar o uso da triangulação em teses e dissertações da área da Administração no Brasil. Com base nos trabalhos encontrados no banco de teses e dissertações da CAPES, foi realizada a análise dos trabalhos, buscando identificar as metodologias empregadas nos estudos e, posteriormente, analisar e exemplificar a utilização dos diferentes tipos de triangulação nas pesquisas encontradas. Os resultados demonstram ser possível encontrar, no escopo de teses e dissertações brasileiras da área da administração, a utilização de todas as tipologias (entre métodos, intra-método, de dados, de teorias e de pesquisadores) presentes na literatura, com predomínio da triangulação entre métodos. Por outro lado, identificou-se uso escasso da triangulação de teorias. Conclui-se que a triangulação é um procedimento que tem contribuído com o rigor científico, em teses e dissertações, e possibilitado a ampliação do entendimento de diversos temas e fenômenos na área da Administração no país.
Flora da Bahia: Loganiaceae
Authors: Brandão Ellen Kallyne de Sousa , Rapini Alessandro
Published: June 2018

Here, we present the treatment of the Loganiaceae of Bahia state. Three genera and 42 species are recognized, representing more than 90% of the species of Loganiaceae from Northeast Brazil. Besides Antonia ovata, 21 species of Strychnos (2 endemic to Bahia) and 20 of Spigelia (8) were reported. The treatment includes descriptions, illustrations, identification keys for native genera and species, as well as comments and maps of the geographical distribution of species in Bahia.
Educomunicación y promoción de la salud [Editorial]
Authors: Gurpegui-Vidal Carlos , García-García Francisco
Published: June 2018

La escritora Karen Blixen apuntaba que “la cura para todo es siempre agua salada: el sudor, las lágrimas o el mar”. En el más que iniciado siglo XXI, también Internet y sus pantallas pueden ayudar en la tarea de sanar. El enfoque de la salud pública centrado en la prevención está dando un giro, marcado por la creación de capacidad y diferentes estrategias lideradas por y para la comunidad, que invitan a adoptar nuevos roles e incorporar nuevas herramientas de innovación para nuevos foros de divulgación científica y de transferencia de conocimiento: los escenarios de educación mediática para una nueva alfabetización sanitaria, la salutogénesis, el humanismo digital y las tecno-utopías, los protocolos de buenas prácticas en salud con Internet y la social media, las nuevas mediaciones para nuevos contextos, etc.
Management of Arthrofibrosis of the Knee after an Arthroscopic Meniscectomy with Paralytic Shellfish Poisoning Toxin. Case Report.
Authors: Hinzpeter Jaime , Zamorano Alvaro , Barahona Maximiliano , Möller Germán , Espinoza Joaquín , Campo Miguel del , Piron Robin , Sepúlveda Joaquín M. , Bustamante Tamara , Lagos Nestor
Published: June 2018

Objective:
The purpose of this study is to evaluate the use of paralytic shellfish poisoning toxin in a patient with arthrofibrosis of the knee. Arthrofibrosis is a common complication of knee surgery that tends to manifest itself as a limitation of the musculoskeletal ranges. Paralytic shellfish poisoning toxin has been proposed as an alternative treatment for painful musculoskeletal pathologies.

Subjects:
Use of paralytic shellfish poisoning toxin in arthroscopic menisectomy. Case report.

Methods:
Three doses of paralytic shellfish poisoning toxin were administered in an intra-articular manner on different days. Functionality, musculoskeletal ranges, pain at rest and pain during motion were evaluated.

Results:
The current alternatives for management of arthrofibrosis include the use of oral steroids, physiotherapy, mobilization under anesthesia and the liberation of arthroscopic debris. This case is the first report of the use of paralytic shellfish poisoning toxin. The adverse effects the patient presented coincided with those described in the literature but without the presence of severe reactions.

Improvement in functional tests, progress in musculoskeletal ranges and a decrease in the level of pain were achieved. Adverse effects included parenthesia and a feeling of weightlessness.
Tanycytic Ependymoma of the Filum Terminale Region; a Case Report
Authors: Petrovic Marko , Miletic-Kovacevic Marina , Jovanovic Nemanja , Nikolic Radivoje , Raicevic Savo , Kovacevic Vojin
Published: June 2018

Tanycytic ependymoma is a very rare spindle-cell variant of ependymoma derived from tanycytes, which are part of the primitive nervous system. This paper is presenting 48-year old woman who presented with low back and right-sided leg pain of moderate intensity. MRI showed spinal intradural tumor at the level of the L1 vertebral body. Right-sided L1 hemilaminectomy and en bloc tumor resection were performed. Neuroradiological and intraoperative diagnosis of schwannoma was revised to tanycytic ependymoma after careful immunohistochemical analysis. Six months post-operativly, MRI did not show tumor recurrence. Tanycytic ependymoma at the region of filum terminale is extremely uncommon and only three cases have been described in the literature. The low incidence of this tumor and atypical histological image, which is distinct from the typical features of commonly encountered ependymomas, can present a challenge in terms of making an accurate diagnosis. Awareness of this transitional form of ependymoma among neurosurgeons and pathologists may avoid incorrect surgical approaches and postoperative treatment course.
A Mathematical Model Governing Tornado Dynamics: An Exact Solution of a Generalized Model
Authors: Pandey Sanjay Kumar , Maurya Jagdish Prasad
Published: June 2018

We investigate in this paper the dynamics of tornadoes by considering that the real inflow radial velocity depends on both the radial and vertical coordinates. The formulation is based on the model for the radial velocity that has been deduced from an experimentally verified model of azimuthal velocity. We present an analytical model for steady, incompressible, and viscous fluids and try for exact solutions. Although all the three components depend on radial and axial coordinates, viscosity affects merely the azimuthal velocity and the pressure. It is observed that the magnitude of the radial velocity increases to the maximum at the core but reverses the trend beyond and vanishes as it reaches the centerline. The magnitude reduces linearly with axial distance as per the supposition. At the core, the larger the Reynolds number, the lower is the velocity for moderate Reynolds numbers. Insignificant impact is observed for very large Reynolds number. However, inside and outside the core, the trends are reversed. Radial pressure distributions for different axial positions are similar to theoretical, numerical, and experimental observations. As we move outward from the axis, pressure increases. The difference between the pressures at the axis and that in outward regions increases with height. Pressure falls with rising Reynolds number uniformly for all radial distances. This is an indication that quantitative difference in pressure is large between viscous and inviscid flows.
Thiosugars, 17. Preparation and structure of a novel deoxythionucleoside
Authors: Voss Jürgen , Otzen Dirk , Adiwidjaja Gunadi
Published: June 2018

1-(3′,5′-Anhydro-2′-deoxy-3′-thio-D-lyxo-furanosyl)thymine is prepared from the corresponding methyl pentofuranoside by using the silyl Hilbert–Johnson reaction. The α- and β-anomers are separated by column chromatography and their configuration is elucidated by NMR spectroscopy and, in case of the α-anomer, by an X-ray structure determination.
Work-Life-Balance und Arbeitsbedingungen von wissenschaftlichen Mitarbeiterinnen und Mitarbeitern in Deutschland
Authors: Lenkewitz Sven , Möhring Katja
Published: June 2018

Die Arbeitsbedingungen von wissenschaftlichen Mitarbeiterinnen und Mitarbeitern in Deutschland sind durch eine ambivalente Mischung aus hoher Autonomie und interessanten Arbeitsinhalten einerseits, unsicheren Arbeitsverhältnissen und unklaren Karriereaussichten andererseits geprägt. Wir analysieren die Einflussfaktoren der work-life balance in dieser Gruppe und beziehen sowohl den Konflikt von Arbeit und Privatleben (work-life conflict) als auch die wechselseitige Bereicherung (work-life enrichment) ein. Für die empirischen Analysen verwenden wir Daten einer Onlinebefragung von 96 wissenschaftlichen Mitarbeiterinnen und Mitarbeitern in den Sozial- und Wirtschaftswissenschaften einer deutschen Universität aus dem Jahr 2015. Mit linearen Regressionsanalysen untersuchen wir, wie Arbeitsbedingungen und -ressourcen work-life conflict und work-life enrichment beeinflussen. Zentrales Ergebnis unserer Analyse ist, dass insbesondere befristete Verträge und Wochenendarbeit den work-life conflict erhöhen. Eine gute Arbeitsatmosphäre im Team trägt hingegen zu einer Bereicherung des Privatlebens bei.
Landscapes of life and conflict in northern Spain: the ‘Monte Bernorio in its Environment’ project
Authors: Torres-Martínez Jesús F. , Fernández-Götz Manuel
Published: June 2018

Archaeological investigations at Monte Bernorio (northern Spain) and its surroundings are yielding exciting new evidence for the destruction of the Iron Age oppidum by the Roman military and the subsequent Roman occupation of the area.
Documenting, disseminating and archiving data from the Teotihuacan Mapping Project
Authors: Huster Angela C. , Cabrera-Cortés Oralia , Forest Marion , McManamon Francis P. , Robertson Ian G. , Smith Michael E.
Published: June 2018

The Teotihuacan Mapping Project (TMP) provided vast quantities of invaluable data to our understanding of this famous ancient city. The ‘Documenting, Disseminating, and Archiving Data from the Teotihuacan Mapping Project’ aims to analyse, re-examine and ultimately coalesce TMP data for entry into The Digital Archaeological Record.
The expanding and deepening scope of historical archaeology
Authors: Mrozowski Stephen A.
Published: June 2018

2017 marked the fiftieth anniversary of the founding of both the Society for Historical Archaeology, in North America, and the Society for Post-Medieval Archaeology, in the UK. Each society celebrated this milestone by publishing a collection of forward-looking essays in their respective journals (see Brooks 2016; Matthews 2016). Although each group of practitioners has followed what might be best described as parallel, but not convergent, intellectual tracks, what they have shared is a common focus on the period of European expansion and colonialism starting in the late fifteenth century. Since that time, the two fields have grown much closer, while the larger intellectual project that is historical archaeology has seen its popularity grow across the globe. In many respects, these three volumes, while different, nevertheless provide a rich collection of chapters that reveal both the widening and deepening of the field.
EDITORIAL
Authors: Witcher Robert
Published: June 2018

When John F. Kennedy described Washington, D.C. as a city of Southern efficiency and Northern charm, it was presumably not intended as a compliment. Nonetheless, like all good quotes, it captures a wider truth—a capital city as the pivot of a vast and diverse nation, a symbolic and political, if not geographic, centre. In this sense, the choice of Washington, D.C. to host the 83rd Annual Meeting of the Society for American Archaeology (SAA), 11–15 April 2018, was more than coincidence. With a still relatively new administration in the White House making policy changes with significant implications for the nation's cultural heritage, the gathering of more than 5000 archaeologists from the USA and beyond offered the opportunity to lobby politicians and policymakers on their home turf. Delegates were accordingly encouraged to contact their elected representatives, and the SAA Government Affairs Program pursued meetings on Capitol Hill to press the case for the protection and promotion of cultural heritage. The theme was reinforced through the SAA Presidential Sponsored Forum, entitled ‘Bears Ears, the Antiquities Act, and the Status of our National Monuments’, where the panel reflected on the effectiveness of the Antiquities Act of 1906 (now safeguarding over one million square kilometres of US territory) and the emerging threats to the protection it provides. In particular, the unprecedented proposal by the new administration to reduce significantly the size of one of the most recent additions to the list, the Bears Ears National Monument in Utah (as well as Grand Staircase-Escalante National Monument), has led to concerns—and lawsuits—over political interference and the weakening of the protection that the Act provides for sites and landscapes across the USA.