bluuebunny/crossref_metadata_2025 huggingface dataset:
Autoreactive CD8 T cells in NOD mice exhibit phenotypic heterogeneity but restricted TCR gene usage
Authors: Kasmani Moujtaba Y , Ciecko Ashley E , Brown Ashley K , Petrova Galina , Gorski Jack , Chen Yi-Guang , Cui Weiguo
Published: June 2022

Type 1 diabetes (T1D) is an autoimmune disorder defined by CD8 T cell–mediated destruction of pancreatic β cells. We have previously shown that diabetogenic CD8 T cells in the islets of non-obese diabetic mice are phenotypically heterogeneous, but clonal heterogeneity remains relatively unexplored. Here, we use paired single-cell RNA and T-cell receptor sequencing (scRNA-seq and scTCR-seq) to characterize autoreactive CD8 T cells from the islets and spleens of non-obese diabetic mice. scTCR-seq demonstrates that CD8 T cells targeting the immunodominant β-cell epitope IGRP206-214exhibit restricted TCR gene usage. scRNA-seq identifies six clusters of autoreactive CD8 T cells in the islets and six in the spleen, including memory and exhausted cells. Clonal overlap between IGRP206-214–reactive CD8 T cells in the islets and spleen suggests these cells may circulate between the islets and periphery. Finally, we identify correlations between TCR genes and T-cell clonal expansion and effector fate. Collectively, our work demonstrates that IGRP206-214–specific CD8 T cells are phenotypically heterogeneous but clonally restricted, raising the possibility of selectively targeting these TCR structures for therapeutic benefit.
Fakülte Bünyesinde Yürütülen Turizm İşletmeciliği Bölümü Müfredatlarının Betimsel ve İçerik Analizi
Authors: ZAFER  KAVACIK Saadet , ÇINAR Kevser , KAVACIK Mustafa
Published: June 2022

Türkiye’de Fakülte bünyesinde eğitim veren Turizm İşletmeciliği bölümü müfredatlar ının genelini temsil edecek düzeyde daha önce betimsel ve içerik analizin yapılmamış olması nedeniyle mevcut çalışmanın bu boşluğu doldurması hedeflenmekte ve Turizm İşletmeciliği bölümü müfredat derslerinin temalar aracılığıyla resmedilmesi amaçlanmıştır. Araştırma örneklemini Türkiye’deki 45 farklı üniversitedeki 54 Turizm İşletmeciliği müfredatı oluşturmaktadır.Araştırmada yorumlayıcı paradigma benimsenmiş ve doküman incelemesi ile toplanan toplam 5161 adet ders ve program detay bilgilerinin MAXQDA Analytics Pro 2022 programı aracılığıyla betimsel ve içerik analizi yapılmıştır. Yapılan analizler neticesinde ulaşılan sonuçlara göre lisans düzeyinde farklı fakültelerde verilen Turizm İşletmeciliği müfredat derslerinin standart bir yapıda olmadığı ve çok farklı ders ve modüllerden oluştuğu görülmüştür. Araştırmada hem devlet hem de vakıf üniversitelerinde en fazla “yönetim” temasıve yönetimin alt kodları içerisinde ise “genel yönetim” derslerinin yer almaktadır. Turizm İşletmeciliği bölümü %75’e yakın oranda daha çok Turizm Fakültesi bünyesinde yürütülmekte,program dili ve ders dilinin daha çok Türkçe olduğu tespit edilmiştir.
A qualitative examination of the experiences of defence lawyers in working with emotional material in the criminal law
Authors:   , Ravera Daniela
Published: June 2022

This qualitative study investigated New Zealand defence lawyers’ experiences working with emotional material in their role. Fourteen defence lawyers across New Zealand participated in semi-structured interviews. Data were analysed using reflexive thematic analysis to identify patterns of experiences across participants. Four themes were identified that related to defence lawyers’ experiences of working with emotional material: industry expectations versus the role reality, managing emotions in the moment, personal conflict of working in a broken criminal justice system, and factors that help and hinder wellbeing while working with emotions. These findings add to the under-researched area of legal professionals’ experiences of emotion. They indicate that defence lawyers engage with emotions from different sources, including clients, difficult case material, and other legal professionals. Defence lawyers are required to engage in a range of emotion regulation strategies to manage both their own emotions and those of others to protect their wellbeing. This emotional management must be performed within the expectations and standards of the criminal justice system and the legal profession. The need for further research, policy and practice to support defence lawyers in their role is discussed, specifically about providing education and support services to support their wellbeing.
Beating on the Drum of War: The Hausa Fulani Hegemony and Restructuring Agenda in Nigeria
Authors: Alfa Patrick Innocent , Ibn-Mohammed Isah , Eikojonwa Otaida
Published: June 2022

Background: It has been argued by sections of the Nigerian state that there exists a grand hegemonic game plan by the Fulani at Islamizing Nigeria. Some have argued the current happenings of rampaging banditry as evidence of the plot in itself. As a result of this, some sections of the country are calling the government of the day to “restructure” Nigeria’s federation into a working “true federal” state or have the country seize to exist altogether.

Objective: The objective of this paper is to interrogate the reliability of this theory of Islamization and to investigate the questions that have pulled Nigeria to the bricks of war.

Method: The paper employed qualitative sources and leveraged both academic, grey literature, and newspaper publications as its primary sources.

Findings: The paper found out that the historical suspicion that has existed amongst the Nigerian people since independence is retrogressive and as such anti cohesion.

Implications/Originality/Value: The paper recommends that our common problems of basic infrastructure, security, employment opportunities, social investment among others must be adequately addressed if Nigeria is to halt the drumbeats of war. Therefore, the paper concludes that until the major contradictions inherent within the state are properly tackled, the current problems would continue to reappear even if remedial solutions are found today.
安全标准化管理在泵站工程建设中的具体运用
Authors: 中华 武
Published: June 2022

对泵站工程建设实行标准化、安全化管理可以为工程稳定运行提供保障，对于泵站建设管理而言是必须做到的。但是从现目前的情况看来，在泵站的工程建设管理中还存在较多问题，导致其管理的有效性降低，容易引发安全隐患。因此，对泵站工程建设实施安全标准化管理是当前研究的重点，应当引起高度重视，依据泵站工程建设的现状制定相应的解决措施，确保泵站工程建设管理规范化、合理化，避免安全事故的发生。
房建土建工程中高支模的施工技术
Authors: 锋海 焦
Published: June 2022

随着中国城市化进程的加快，中国房屋建筑施工领域的迅速发展，对施工质量和标准提出了更高的要求。现代科技可以保证房屋建筑的土建工程质量，也可以保证辅助施工。采用高支模法进行施工，可提高结构的稳定性、强度，提高工程建设的质量和水平。论文对高支模在房屋建筑工程中的运用进行了分析，并对其进行了深入的探讨与分析，为今后高质量的房建工程建设打下了坚实的基础。
CFP- Ⅰ型预应力碳纤维板加固空心板梁技术研究
Authors: 风久 沈 , 继茂 王
Published: June 2022

结合20m跨径空心板梁简支梁桥的工程概况，对该桥进行了外观及荷载试验检测，提出了采用CFP-Ⅰ型预应力碳纤维板对其加固利用的方案。对CFP-Ⅰ型预应力碳纤维板加固桥梁设计方案、施工工艺和施工关键技术进行刨析，提高了梁板加固桥梁的施工安全、质量、进度，同时避免了材料的浪费，节约了成本，可以为其他类似工程施工提供借鉴。
浅谈建筑工程中的深基坑支护施工技术
Authors: 晓龙 孙 , 培峰 于
Published: June 2022

城市的发展规划，必然离不开建筑工程。在当前阶段，随着建筑的规模逐渐增加，建筑物的高度也在逐渐增加，这在一定程度上对深地基建筑质量提出更高要求。这主要是因为大型建筑对稳定性的要求比较严格，而如果深基坑支护施工科技的产品质量达不到标准，将会影响到建筑施工的产品质量，甚至有可能危及周边的建筑物，给人民的生命财产带来巨大危险。
超长玻璃幕墙施工技术的研究与应用
Authors: 颖超 张
Published: June 2022

玻璃幕墙外形复杂多变，不可展开曲面应用较多，空间结构复杂，设计和施工难度很大，施工中将面临大量的现场技术问题处理需及时解决，同时还有复杂的协调关系需要处理，要求施工人员具有与所在岗位相适应的思想素质和工作能力。
“By June, Everyone Would Have Died”: Historicising Humour during the Covid-19 Pandemic in Ghana
Authors: Marfo Charles Ofosu , Adu-Gyamfi Samuel , Sanka Confidence Gbolo , Darkwa Benjamin Dompreh , Tomdi Lucky
Published: June 2022

The impact of the COVID-19 pandemic on human interactions deeply affected the sense of humour of individuals. Using a social media research approach, this article analyses social media data in order to understand how social media users related with COVID-19. We sought to address the various events that generated humour among Ghanaians during the pandemic. The study reveals that the various instances of humour revolved around nose and/or face masks, terminologies and various social media posts. People neutralised their tensions and raised their humour with posts that flooded social media. This stemmed from the idea that people were mainly surprised at what they saw, watched or heard as they sought to release stress. We conclude that, owing partially to the creation of humour, the fear and tension associated with COVID-19 decreased with time among Ghanaians.
Effect of Antenatal Betamethasone and Dexamethasone on Maternal Blood Glucose Levels, Fetal Movement, Nst Parameters, and Umbilical Artery Doppler
Authors: Chaurasia Amrita , Singh Vidhi
Published: June 2022

Background: The rationale of the study is to establish the time duration of recovery of disturbed sugar values and NST parameters following steroid administration and which drug has a lesser rate of hyperglycemia and lesser disturbance of DFMC and NST parameters, so as to advocate better drugs for fetal lung maturity. This study aims to compare the changes in maternal serum glucose levels, daily fetal movement count, NST parameters, and umbilical artery doppler following Betamethasone and Dexamethasone administration in antenatal women.
Subjects and Method: The study design is a prospective observational cohort study. 100 pregnant patients, were recruited into 2 equal groups who received Betamethasone and Dexamethasone in Obstetrics & Gynaecology department, MLN Medical College, Prayagraj. The independent variables are Age, Gravidity, and BMI while the dependent variables are postprandial blood sugar values, Daily Fetal Movement Count, Fetal Heart Rate, Non-Stress Test Parameters, and Doppler Flow Veloci- metry of the Umbilical artery. Categorical variables were compared using the Chi-square test, while, for continuous variables T-test was used. Study instruments include Glucometer, Cardiotocography, and Ultrasound.
Results: Significant changes in the glycemic profile and fetal movements were noted. The mean ± SD glucose rise after 24 hrs in Group A (Mean= 140.10; SD= 35.90) and group B (Mean= 113.26; SD= 27.90), with p<0.001. 54% and 24% women perceived reduced fetal movements (p = 0.002) while 14% and 12% women had reduced variability on NST (p = 0.766) in Group A and Group B respectively, with 66.6% and 85.71% showing reduced flow on Doppler.
Conclusion: Antenatal Betamethasone as well as Dexamethasone administration causes significant changes in maternal hyperglycemia, FHR, and DFMC at 24hrs while changes were non-significant in NST parameters and Doppler. Maternal hyperglycemia resolved within 72hrs with a resolution of decreased fetal movement perception. Umbilical artery flow decreased 24 hrs following steroid administration with more profound changes with betamethasone.
Does Husband Support Associated with the Duration of Breastfeeding?
Authors: Pratiwi Bintang Agustina , Lesmi Anisa , Husin Hasan , Angraini Wulan , Suryani Desri
Published: June 2022

Background: Breastfeeding coverage in the Bengkulu ranks second lowest (68.9%) in Indonesia. The husband is the closest person mother who can support successful breastfeeding up to 2 years. This study aimed to examine the effect of husband support on the duration of breastfeeding.
Subjects and Method: This was a cross sectional study. A sample of 44 fathers who had children aged 2-3 years in Lingkar Barat community health center, Bengkulu, was selected for this study. The dependent variable was breast­feeding duration. The independent variable was informational support, assessment support, instrumental support and emotional support. Data collection using a valid and reliable questionnaire. Data analysis was performed using multiple linear regression.
Results: The results showed the informational support (b= 0.37; 95% CI= -0.07 to 0.75; p= 0.046), apprisial support (b= 0.29; 95% CI= -0.39 to 0.98; p= 0.393), and instrumental support (b= 0.43; 95% CI= -0.18 to 1.05; p= 0.161) were positively associated with the duration of breastfeeding. Emotional support was negatively associated with the duration of breastfeeding (b= -0.37; 95% CI= -1.03 to 0.29; p= 0.252).
Conclusion: Husband's support is associated with length of breastfeeding.
Comparisons of SVM Kernels for Insurance Data Clustering
Authors: Nurhidayat Irfan , Pimpunchat Busayamas , Noeiaghdam Samad , Fernández-Gámiz Unai
Published: June 2022

This paper will study insurance data clustering using Support Vector Machine (SVM) approaches. It investigates the optimum condition employing the three most popular kernels of SVM, i.e., linear, polynomial, and radial basis kernel. To explore sum insured datasets, kernel comparisons for Root Mean Square Error (RMSE) and density analysis have been provided. It employs these kernels to classify based on sum insured datasets. The objective of this research is to demonstrate to industrial researchers that data grouping may be accomplished in an organized, error-free, and efficient manner utilizing R programming and the SVM approach. In this study, we check the insurance data for the sum insured with statistical methods in the form of Model Performance Evaluation (MPE), Receiver Operating Characteristics (ROC), Area Under Curve (AUC), partial AUC (pAUC), smoothing, confidence intervals, and thresholds. Then, sum insured data are followed up to classify using SVM kernels. This paper finds new ideas for evaluating insurance data using the SVM approach with multiple kernels. This novel research emphasizes the statistical analysis methods for insurance data and uses the SVM method for more accurate data classification. Finally, it informs that this research is a pure finding, and there has never been any research on this subject. This research was conducted using the sum insured data as a sample from the Office of the Insurance Commission (OIC) in Thailand as an independent insurance institution providing actual data. Doi: 10.28991/ESJ-2022-06-04-014 Full Text: PDF
Yapay Zekâ Etiği: Toplum Üzerine Etkisi
Authors: TURAN Tülay , TURAN Gökhan , KÜÇÜKSİLLE Ecir
Published: June 2022

Yapay zekâ sistemlerini, günümüzde toplumun temel rollerine hizmet eden, birçok uygulama alanında bizlere fayda sağlayan ve gelecek yıllarda belki biz insanlara ihtiyaç duymadan, özerk kararlar alabilen sistemler olarak tanımlayabiliriz. Yapay zekâlı sistemlerin giderek daha fazla özerklikle, yani daha az insan denetimi ile çalışabilmesi için öncelikle etik yapılarının oluşturulması gerekmektedir. Etik yapay zekâ, bireysel haklar, mahremiyet, eşitlik ve ön yargı yapmama gibi temel değerlerle ilgili iyi tanımlanmış etik yönergelere bağlı kalan yapay zekâdır. Yapay zekâ etik uygulamaları, kuruluşların daha verimli çalışmasına, daha temiz ürünler üretmesine, zararlı çevresel etkileri azaltmasına, kamu güvenliğini artırmasına ve insan sağlığını iyileştirmesine yardımcı olacaktır. Etik olmayan yapay zekâ uygulamaları ise toplum için ciddi zararlı etkilere neden olabilecektir. Bu olumsuz etkileri sorumlu bir şekilde yönetmek ve yapay zekâ sistemlerini toplum yararına yönlendirmek için en önemli çözüm, etik yapay zekâ sistemlerinin geliştirilmesidir. Son yıllarda akademi, endüstri, hükümet ve sivil toplum tarafından yapay zekâ etiği ile ilgili yapılan çalışmalar bir temel sağlamaya başlamıştır. Bu çalışmada, yapay zekâ etiği ve toplum üzerine etkisi, iş gücü piyasası, eşitsizlik, gizlilik ve ön yargı konu başlıkları üzerinde tartışılıp, olası risklere ve tehditlere dikkat çekilmekte ve çözümü için önerilerde bulunulmaktadır.
Megatendencias del Sector Restaurantero
Authors: Hernández Gracia Tirso Javier , López-García Susana , Duana-Avila Danae
Published: June 2022

El sector restaurantero ha sufrido afectaciones a partir de la pandemia COVID-19, principalmente en su economía, por ello, debe buscar o cambiar sus estrategias y actualizarse a los nuevos requerimientos que el consumidor exige al haber modificado sus hábitos de consumo. En el presente artículo se realiza una revisión documental para analizar las principales megatendencias que están por revolucionar el servicio de alimentos y bebidas y a las cuales es preciso atender si se desea seguir permaneciendo en el mundo competitivo y trascendente.
Elaboración de capuchino con prensa francesa y prensa italiana
Authors: Vázquez Hernández Alexia , Onofre Sánchez Jair Emmanuel , Ramírez Godínez Juan
Published: June 2022

Anteriormente se dudaba si el café era algo “bueno” para la salud, hoy día se sabe que está famosa bebida compuesta de elementos como polifenoles, diterpenos o ácidos clorogénicos, así como cafeína tiene efectos antioxidantes y antiinflamatorios, de igual forma hoy día se sabe que la cantidad de cafeína que se puede encontrar en la bebida va a depender del método de extracción así como de la calidad del grano por lo que ya no representa un problema para la salud, sino un disfrute al paladar.
Uso del betabel (Beta vulgaris) como tratamiento alternativo en la anemia ferropénica
Authors: Gómez Cipriano Jennyfer , Zafra Rojas Quinatzin Yadira , Cruz Cansino Nelly del Socorro , Martínez Román María Elena , Ramírez Moreno Esther , García Rosales Rubén Uziel
Published: June 2022

El betabel (Beta vulgaris) es una hortaliza de uso versátil que aporta amplios beneficios a la salud por lo cual se ha utilizado como terapia en diversas enfermedades, debido a su alto contenido en vitaminas, minerales, fibra y antioxidantes. Una aplicación de interés del consumo del betabel es a causa de su alto contenido de hierro, mineral que favorece al aumento de hemoglobina sérica en la anemia ferropénica. Por lo tanto, el objetivo del presente manuscrito fue mostrar evidencia sobre el uso de betabel en el tratamiento de la anemia ferropénica, mediante una revisión de las investigaciones más recientes. Las intervenciones reportan que el consumo de 200 mL de jugo de betabel en ayunas favorece la absorción intestinal de hierro por un periodo de 6 semanas, lo cual ayuda a aumentar las concentraciones de hemoglobina (14.21 g/dL), hierro sérico (86.10 µg/dL) y ferritina (37.09 ng/dL), además de eliminar síntomas asociados con la anemia como debilidad, fatiga, palpitaciones, intolerancia al esfuerzo y disnea.
Democracia participativa
Authors: Trejo Victor Olid , González-Victoria Rosa María , Valles Ruiz Rosa María
Published: June 2022

En este trabajo se expone una aproximación al proceso de diseño de un Reglamento de Participación Ciudadana en un municipios del país caracterizado por estar situado en una de esas entidades federativas que han sido gobernadas, durante nueve décadas consecutivas, por un solo partido, concebido hasta hace algunos años como el partido oficial. Como objetivo de una investigación más amplia, de donde proviene este artículo, se buscó observar y obtener, mediante un proceso de Investigación Acción Participante, elementos, esquemas y comportamientos ciudadanos al intervenir en asuntos públicos.
Post Tsunami Land Use Monitoring to Support Sustainable Coastal Management
Authors: Utami Westi
Published: June 2022

Monitoring of land use in tsunami prone coastal areas has an important role in disaster risk reduction efforts. This study was conducted to map temporal land use patterns in the post-2004 tsunami Aceh coastal area. The research method was carried out qualitatively, the data were analyzed spatially, by interpreting multitemporal Landsat TM 5 and Landsat 8 imagery to determine patterns and changes in land use. Interpretation and analysis of land use are carried out with supervised classification through the maximum likelihood approach. The results showed that land use patterns in tsunami prone areas, namely around the coast, were still widely used as residential areas. This study shows that over the past 15 years there has been an increase in the number of settlements covering an area of ​​7418.9796 hectares, and there has been a decrease in open land covering an area of ​​6743.73 hectares. While land use in the form of high density vegetation experienced an increase of 672.76 Ha, likewise low density vegetation increased by 459.11 Ha after the tsunami. The growth of settlements in a fairly dense tsunami-prone area can have implications for the high impact / risk if a similar disaster occurs again. Efforts to regulate, monitor, control and evaluate land use appropriately in tsunami prone areas are necessary so that the level of disaster risk can be reduced.
RUSLE-based soil erosion assessment and erosion control evaluation in the Kabul Watershed
Authors:   Hydraulic Structures Engineering Department, Kabul Polytechnic University, Kabul, Afghanistan, Patyal Samiullah
Published: June 2022

The development and conservation of water and soil in the Kabul River Basin are critical for ensuring its sustainable economic, social, and environmental progress. Since the watershed drains across the international borders into the Indus River Basin, it is key for both up- and downstream countries to thoroughly plan their resource development and management. Due to relief, soil and climatic conditions, as well as the recent deforestation the Kabul River Basin has been witnessing significant soil erosion by water, indicating the need for analyzing its specifics and deploying proper control measures. This study was carried out using the combination of the Revised Universal Soil Loss Equation (RUSLE) Model and GIS techniques to investigate the gross soil loss rates and their spatial distribution inside the target basin. Thus, the annual average soil loss rate was estimated at 15.1 tons/ha/year, pointing to severe local soil erosion. As to its spatial distribution, according to the study up to 99% of mean annual soil loss rates fell within the tolerable (0-5 tons/acre/year) category. Considering the soil loss rates, local topography, and community-based participatory approaches, the authors recommend conducting a further detailed diagnostic analysis to inform and support subsequent control measures such as deforestation prevention, construction of small check dams, terracing, trenching in hilly areas, revegetation (reforestation) of open- and grasslands, and rainwater harvesting.
Some Special Graphs of Quaternion Group
Authors: Gazir S Abdul , Wardhana I Gede Adhitya Wisnu
Published: June 2022

Research on an algebraic structure represented in graph theory opens the way for new research in recent years. Several types of new graphs continue to be developed, such as coprime and non-coprime graphs. This article will represent the quaternion group in several graphs, such as coprime graphs, non-coprime graphs, commuting graphs, non-commuting graphs, and identity graphs. We obtained several theorems about unique graphs. One of the results is that non-coprime graphs from the quaternion group are complete and regular graphs.
Pipeline Network Optimization using Hybrid Algorithm between Simulated Annealing and Genetic Algorithms
Authors: Hidayatullah Parizal , Irwansyah Irwansyah , Aini Qurratul , Syechah Bulqis Nebula
Published: June 2022

The pipeline network is one of the most complex optimization problems consisting of several elements: reservoirs, pipes, valves, etc. The pipeline network is designed to deliver water to consumers by considering the demand and adequate pressure on the water pipe network. The main problem in designing reliable pipelines is the cost. The amount of cost that most influences the design of pipelines is the diameter of the pipe used. Therefore, this study aims to combine (hybrid) simulated annealing algorithm with genetic algorithm to optimize water pipe networks. The simulated annealing algorithm is the main algorithm in finding the optimal cost.Meanwhile, the genetic algorithm will assist in the pipeline update process using the roulette wheel selection. Simulation data is used to test the hybrid algorithm performance compared to the standard simulated annealing algorithm. The results show that the simulated annealing hybrid algorithm is able to get a more optimal cost in designing a water pipe network compared to the standard simulated annealing algorithm. Keywords: Optimization, Epanet 2.0, Simulated Annealing, and Genetic Algorithm
Comparison of Fuzzy Time Series Methods and Autoregressive Integrated Moving Average (ARIMA) for Inflation Data
Authors: Qalbi Asyifah , Nurfadilah Khalilah , Alwi Wahidah
Published: June 2022

This study compares the Fuzzy Time Series (FTS) method with the Autoregressive Integrated Moving Average (ARIMA) method on time series data. These two methods are often used in predicting future data. Forecasting or time-series data analysis is used to analyze data in the form of time series. In this study, Indonesian inflation data was used to be analyzed in comparing the FTS and ARIMA methods. Inflation is one of the economic indicators used to measure the success of a country's economy. If the inflation rate is low and stable, it will stimulate economic growth. This inflation value is calculated every month where the value can decrease and increase from one period to another. Comparison of the FTS and ARIMA methods is seen in the error value generated by the two methods. A method can be better than other methods if the value of the resulting forecast error is smaller. In this study, Mean Squared Error (MSE) and Mean Absolute Percentage Error (MAPE) were used to see the magnitude of the error value of the two methods on the fives data testing used. The results obtained in this study are the results of Indonesia's inflation forecast for the period January to May 2021 using the FTS method, respectively, at 0.57%, 0.375%, 0.2%, 0.2%, and 0.1125%, while the forecast results using the ARIMA method, respectively. Of 0.3715848%, 0.2362817%, 0.1508295%, 0.1731906%, and 0.2432851% and the results of calculating the size of error using MSE and MAPE indicate that the ARIMA method with the model ARIMA(3,0,0) is better at predicting inflation data in Indonesia with a value of MSE of 0.009 and MAPE of 64.987% compared to the FTS method resulted in MSE values of 0.047 and MAPE of 132.548%.
Fuzzy Metric Space and Its Topological Properties
Authors: Masriani Masriani , Aini Qurratul , Bahri Syamsul
Published: June 2022

The fuzzy set theory is mathematics that applies fuzziness characteristics, so that gives the truth value at interval [0,1]. It is different from the crisp set that gives a truth value of 0 if it is not a member and 1 if it is a member. The theory of fuzzy sets has been developed continuously by scientists. One of the developments of the fuzzy set is the fuzzy metric space which the definition was introduced by George and Veeramani. Based on the analysis results, it is found that every metric space X if and only if X is fuzzy metric space. As a result, the topological properties of the metric space still apply to the fuzzy metric space
Profile of Technological Pedagogical And Content Knowledge (TPACK) Middle School Teachers in Sekarbela District, Mataram City
Authors: Ismail Ismail , Muhammad Muhammad , Bahtiar Bahtiar
Published: June 2022

Teachers with TPACK perspectives are teachers who understand the correct pedagogy and conceptual understanding by using technology in teaching subject matter. By having the right TPACK, teachers will be able to engage and motivate students in exploring learning content to a greater extent. This study examines the TPACK profile of junior high school teachers in the Sekarbela sub-district of Mataram city using the TPACK framework. This research is ex-post-facto research and causal associative research with a quantitative approach. The population in this study were junior high school teachers in Sekarbela District, Mataram City, totaling 120 teachers, with a sample of 60 teachers who were taken using a proportional random sampling technique. The data collection technique used questionnaires and documentation, while the data analysis technique used multiple regression using SPSS for windows 21. The results showed that the component of Technological Content Knowledge scored 36.50, which fell into the low category. Pedagogical Knowledge (PK) got a score of 54.80, Technological Knowledge (TK) got a score of 40.83, Content Knowledge (CK) got a score of 47.97, and Technological Pedagogical Knowledge fell into the medium category. Meanwhile, Pedagogical Content Knowledge (PCK) scored 60.93, and Technological, Pedagogical, and Content Knowledge (TPACK) scored 63.53, which fell into the high category. Hence, it can be concluded that the research results show the average overall ability of teachers in the seven TPACK frameworks has a score of 50.07 within high criteria.
Pituitary gland metastasis from breast cancer: case report
Authors: Mohamed Almadhoni , Mohamed Ali Baggas
Published: June 2022

Cancer metastasis to the pituitary gland is rare, but in most cases, it originates from a late-stage breast tumor or lung cancer. The most common symptoms of metastasis to the pituitary gland are diabetes insipidus and visual disturbance. The common site of metastasis is the posterior portion of the pituitary gland because it is highly vascularized. Metastases to this site represent 1% of all tumors [1]. Metastasis to the pituitary gland is difficult to diagnose by hormonal analysis and magnetic resonance imaging of the brain and requires biopsy for confirmation [2]. The recent increase in survival of cancer patients and the advancement in diagnostic techniques have resulted in a more frequent diagnosis of breast and lung cancer metastasis to the pituitary gland, which has a poor prognosis [3,4].
Listening Teaching Strategies in Online Learning
Authors: Tarigan Adinda Maharani , Pohan Ikhwan
Published: June 2022

This study discusses Listening Teaching Strategies in Online Learning. The reason the researcher chose this discussion is that listening is one of the important points in English, where teachers need important strategies to convey every material in listening learning, both directly and through online learning. The researcher's aim in this study was to understand listening teaching strategies in online learning, and the collection method chosen by the researchers in this study was qualitative because the researchers collected data directly through questionnaires given to respondents. All the information that the researchers obtained in this study came from respondents, namely 10 English teachers who teach in junior high schools and have experience teaching listening material to students, either directly or through online learning. The data researcher obtained in this study was sourced from respondents' answers, in this study the researchers discussed in detail and accurately related to Listening Teaching Strategies in Online Learning that can be proven true.
Keywords: Online Learning; Listening; Teaching Strategies
Media Komunikasi Pemasaran Digital Marketing Produk Umkm Selama Pandemi Covid-19
Authors: Mujayana Marya , Santoso Rudi
Published: June 2022

This research focuses on the efforts of MSMEs to utilize digital means for marketing activities or processes. MSMEs use this digital facility for marketing communications to increase purchase intensity during the COVID-19 pandemic. This study uses a qualitative descriptive method with a literature review approach. This study aims to describe the condition of the object of research objectively based on visible facts and data. The thing of this research is 100 MSME entrepreneurs in Madiun Regency. The study results show that the communication strategies carried out by MSME actors in dealing with the pandemic are diverse. The use of digital marketing using social media platforms can increase brand awareness of MSME products. The use of digital marketing as a means of marketing communication has also been proven to increase the intensity of purchases, which has an impact on increasing income. The use of social media and the Marketplace as a means of selling has proven to be used as a medium to increase sales and, at the same time, a strategy to survive during the pandemic.
Estrategias de protección renal en Anestesiología y Cuidados Críticos
Authors: Maria Belén Lozano Serrano  , Beatriz Carretero De La Encarnación  , Luisa Maria Charco Roca
Published: June 2022

En el contexto perioperatorio, el daño renal agudo (acute renal injury o AKI) es una complicación frecuente. Por sí mismo, la presencia de AKI se asocia con resultados adversos, tales como mayor riesgo de enfermedad renal crónica (ERC) y de mortalidad. Varios factores de riesgo están asociados con la aparición de AKI perioperatorio e identificarlos es crucial para iniciar medidas de protección renal.  Algunas estrategias renoprotectoras han demostrado ser útiles, otras se encuentran aún en investigación y otras ya no se recomiendan porque son ineficaces o incluso dañinas. La falta de eficacia de estas terapias podría deberse al hecho de que la terapia se inició demasiado tarde. Los nuevos biomarcadores renales permiten identificar el daño renal sin pérdida de función permitiendo así la implementación de medidas preventivas.  El propósito de esta revisión es mostrar un resumen actualizado de la evidencia actual acerca de los factores de riesgo y los mecanismos que nos conducen a la aparición de AKI perioperatorio y en unidad de cuidados críticos así como las diferentes estrategias y tratamientos renoprotectores.
Como la vida misma. Ensayo clínico pragmático.
Authors: Manuel Molina
Published: June 2022

El ensayo clínico pragmático es el que se realiza en condiciones similares a las de la práctica clínica con el objetivo de valorar el efecto global de una estrategia de tratamiento en el mundo real.
Primer registro fotográfico del gato andino Leopardus jacobita (Carnivora: Felidae) en Pitumarca, Perú
Authors: Guzmán Marín Byron Cristian , Dumont Ailen , Guerrero Jimena
Published: June 2022

En la presente nota reportamos el primer registro fotográfico de gato andino (L. jacobita) en el distrito de Pitumarca, Perú, en el marco del “Proyecto gato andino”. El felino fue fotografiado cuando se encontraba cazando una vizcacha (Lagidium viscacia) en un hábitat rocoso de alta montaña; las características de este registro coinciden con lo reportado anteriormente para la especie a lo largo de su distribución. La existencia de redes viales cercanas a este nuevo registro podría afectar la conectividad entre poblaciones de L. jacobita.
Influence of farming systems practices on physicochemical properties of soils in wet and dry season in University of Port Harcourt, Nigeria
Authors: Chinedum A Ogazie  , Edache B Ochekwu  , Ikechukwu O Agbagwa
Published: June 2022

We evaluated the impact of cultural practices on arable cropped farmlands of more than 5 years of slash, burn, continuous mixed cropping of crops on physicochemical properties of soils in University of Port Harcourt, Nigeria. 22 cultivated arable farmlands and 3 fallow control sampled in June 2020 as wet and January 2021 as dry season 0-15cm depth from 7 auger borings taken randomly from each of the 22 cultivated and 3 fallows farmlands. Samples air dried in laboratory, prepared for analyses, sent to Fatlab in Ibadan Nigeria. Parameters evaluated for physical properties: sand, clay and silt and for chemical properties; pH, Ca, Mg, K, Na and the trace metals; Mn, Fe, Cu, Zn; available P, OC, ECEC, Acidity and Al. The results revealed sandy loam, differences between the mean values for wet season were slightly higher from the dry season, for example pH, Ca, Mg, K, Na, ECEC, Cu, Silt and Clay. The mean value of P in wet season was 5 times higher than dry season. N in wet and dry season mean value were 0.16% respectively; OC was higher in dry season indicating soil healing process before next season cropping. Slight trace of Al in dry season. However, it was significant (p<0.05) between dry and control season, comparison between wet and dry season revealed P, OC, Mg, K, Na, N, Sand and Clay significant (p<0.05). It was observed slash, burn, continuous tillage, mixed cropping of crops and times of the year influence soil physicochemical properties in arable farmland in humid high rain forest.
Medicinal plants with beneficial effects on heart
Authors: Ali Esmail Al-Snafi
Published: June 2022

Cardiovascular diseases (CVDs) kill 17.9 million people per year, by 2030, it is predicted that more than 22.2 million people will die annually from CVDs. Many medicinal plants possessed cardiac and anti-arrhythmic effects. The current study was designed to highlight the medicinal plants which possess beneficial effect in heart failure, protect heart from the toxicity of wide range of chemicals, and exert anti-arrhythmic activities.
A review on therapeutic indications of Jaloukavacharan (medicinal leech therapy)
Authors: Tanuja Marotrao Naik  , Sumedh Vyankatesh Wasnik
Published: June 2022

Since ancient times, Raktmokshana has been one of the best parasurgical therapies indicated in various medico-surgical conditions. It is the course of disposal of vitiated Dosha that collect in the body thus one of the methods of shodhan chikitsa. Among various types of Raktmokshana, jaloukavacharan i.e., leech therapy is more popular now days worldwide. The father of surgery, Acharya Sushruta has described the therapeutic use of leeches. The therapy has been proved absolute safe with obvious advantages which does not cause any unwanted effect. Except hirudin inhibitor of ferment thrombin, there is a whole range of biological active alkaloids combinations. Leech therapy is a good blood purification treatment which has property to die down the aggravation, enlarging, redness and consuming sensation promptly and in which little amount of blood eliminated to vitiated Pitta, Kapha and Rakta dosha of many bloodborne diseases. Earlier the benefits of leech therapy thought to be derived from the amount of blood lost, hence relieving congestion and removing the noxious humors. But subsequent studies have demonstrated that more than the blood loss, it is the salivary secretions of the leech which contain an amazing cocktail of medicinal substances having therapeutic use in many medical & surgical conditions, to reduce post - operative swelling reconstructive surgery and pain relief in various arthritic diseases. Leech therapy is exceptionally beneficial therapeutic strategy which gives desired results. So, it is the need of time to spread awerness about leech therapy and its adequacy. It is the elective treatment promising more powerful and secure results for the society.
A review on the 2-Deoxy-D-Glucose (2-DG) in COVID-19 disease
Authors: Pratik Sunil Kapse  , Samiksha Nandkishor Dhote  , Mahesh Bhanudas Narkhede  , Pavan Prabhakar Chinchole  , Pragati Ramesh Deoche  , Swapnil Datta Gawande
Published: June 2022

This has given a lead to study the role of 2-deoxy-D-glucose (2DG) against COVID-19 (corona virus) disease. We hereby would like to briefly discuss the concept and rationale behind the use of 2DG COVID-19. Virus infections can cause cell damage in many ways. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a cause of the current COVID-19 pandemic, has been extensively studied so far to investigate its pathophysiology and evaluate its impact on the metabolic system of human cells. The Drug Controller General of India (DCGI) has given emergency use approval to 2-deoxy-D-glucose (2-DG), an anti-Covid drug developed by INMAS, a DRDO lab, in collaboration with Dr Reddy's Laboratories (DRL), Hyderabad.
Solutions to recover Vietnam's economy after the nCOV-19 pandemic
Authors: Nguyen Thi Van Anh
Published: June 2022

The Vietnamese government has made significant efforts to restore the country's economic development, with important responsibilities to boost national competitiveness and provide a larger space for enterprises. In addition, the Vietnamese government also offers synchronous solutions from supporting people's lives, developing social security and healthcare, and promoting national security. Policymakers and experts are also discussing specific solutions before being applied nationwide. This promises to be a driving force to recover soon Vietnam's economy, which has been severely affected by the nCOV-19 pandemic.
Bruxism in children: Etiological causes, correlation with intestinal parasitic infestations, diagnosis and treatment criteria
Authors: Docteur Adidémè Monique EZIN
Published: June 2022

Bruxism is defined as a repetitive activity of the masticatory muscles, characterized by teeth clenching or gnashing and/or tapping and rocking. The etiology is multifactorial: mainly central (neuropathic disorder and anxiety) but also genetic and local (posture, mouth breathing). In children, bruxism is very frequent and is not always considered pathological. Several factors have been considered in the etiology of bruxism in children, among which infestations by intestinal parasites, suggested by some authors. It may be one of several symptoms of general pathology. Diagnosis is based mainly on the history and examination of tooth wear and its evolution over time (photos and dental casts). Severity criteria are based on the intensity (number of dental attrition facets) as well as on the context found in the child: anxiety, ventilation problems, and fragility of dental structures. Bruxism management is multidisciplinary and depends on the etiological diagnosis. The objective of this article is to highlight the correlation between bruxism and intestinal parasites and to identify the etiologies, the diagnostic criteria, and the therapeutic scheme of bruxism in children. Publications and research on this subject are few and not consensual. The therapeutic course of action is not clearly defined and the research concerning them remains experimental.
Alopecia areata: Impressive results using low-level laser therapy
Authors: Emily Alice Russu  , Mara Madălina Mihai  , Lucian Emil Russu  , Michael Gabriel Russu  , Maria-Angelica Bencze  , Ştefan-Dimitrie Albu  , Cristina-Crenguța Albu
Published: June 2022

Alopecia areata (AA) is a genetic and autoimmune-mediated disease which specifically targets anagen hair follicles. The disease affects children and adults, men, as well as women, and is characterized by round or oval patches of hair loss. We are presenting here a spectacular case, extremely rare, of AA localized at the level of the scalp, which was successfully treated by Sunetics Laser (Sunetics International, Las Vegas, NV, USA) therapy. Post laser therapy, hair regrowth in the areas that presented hair loss previously, as well as repigmentation, was noted.
Depth, coverage and spacing of the furrows in mechanized sugarcane plantation with planter and distributor in the day and night shifts
Authors: Missio Camilla , Cortez Jorge Wilson , Barreto Ana Karina Gurgel , Silva Marcelei Daniel da , Armando Egas José
Published: June 2022

Mechanized planting, is one of the main operations in the sugarcane production cycle that directly affects the longevity of the shoots, the crop yield and the profitability of the crop. Thus, this study aims to evaluate the furrow depth, furrow coverage and furrows spacing in a mechanized sugarcane plantation with a planter and a distributor in the day and night shifts of operation, using as statistical analysis quality control tool. In both shifts were sampled 30 points, where was collect data of furrow depth, furrow coverage and furrows spacing. The quality indicators of mechanized sugarcane planting are not influenced by the day and night shifts, and present values considered satisfactory when carrying out mechanized planting with a planter or distributor.
Comprimentos de seção e altura de fustes na cubagem rigorosa em diferentes espaçamentos de eucalipto
Authors: Lafetá Bruno Oliveira , Barbosa Isaac Willian Balbatahan Silva , De Oliveira Acálita Godinho , Vieira Diego dos Santos , Penido Tamires Mousslech Andrade
Published: June 2022

Objetivou-se avaliar a influência do comprimento de seções e alturas totais para a quantificação volumétrica de fustes de eucalipto em diferentes espaçamentos de plantio. Os volumes dos fustes com casca foram calculados utilizando-se a fórmula de Smalian, considerando seções de 1, 2, ..., 6 m de comprimento após a posição de 2 m de altura. As posições de cubagem da base foram padronizadas. Realizou-se a modelagem para a estimativa dos erros percentuais em função do comprimento de seção e altura de fustes. As estimativas de erro foram maiores em seções mais longas e fustes de menor altura total. Conclui-se que seções mais longas levam a superestimativas do volume acima da posição de 2 m de altura e, consequentemente, do volume total do fuste. Seções de comprimento superior a 2 m devem ser evitadas em cubagens rigorosas, sobretudo, quando realizadas em talhões instalados sob espaçamentos de 1,5 a 6 m2.
Controle biológico de Fusariose em mudas de Pinus taeda e Pinus elliottii com produto comercial a base de Trichoderma sp
Authors: Tikler Sousa João Arthur , Scheinpflug Brito Gabriela , Santos Rego Suelen
Published: June 2022

O objetivo deste trabalho foi testar a eficiência do uso de produto biológico comercial à base de Trichoderma no controle preventivo do fungo Fusarium sp. em mudas de Pinus taeda e Pinus elliottii. Foram utilizados dois isolados de Fusarium sp., inoculados nas mudas pela imersão das raízes em suspensão de esporos. As mudas inoculadas foram plantadas em tubetes com substrato comercial misturado com uma suspensão do produto biológico e mantidas em casa de vegetação. Após 56 dias foram avaliados a severidade da doença, a altura, o diâmetro do colo, o comprimento da parte aérea, a massa seca da raiz e a massa seca da parte aérea. Os resultados demonstraram que a incorporação de produto comercial à base de Trichoderma harzianum ao substrato das mudas de P. taeda e P. elliottii inoculadas com dois isolados de Fusarium sp. diminuiu a severidade da doença e proporcionou o melhor desenvolvimento das mudas.
Nuevas necesidades y preferencias post-pandemia en el turismo de balneario en España: el caso de Archena (Murcia)
Authors: Pinos-Navarrete Aida , Villalobos-Jiménez Elvira , Maroto Martos Juan Carlos
Published: June 2022

El sector turístico se ha visto fuertemente afectado por la crisis sanitaria de la COVID-19. En este contexto el turismo de balneario, en proceso de reconceptualización hacia el wellness, se enfrenta a un nuevo escenario. El objetivo de la presente investigación es analizar si la conducta y necesidades de los clientes del turismo de balneario en España han experimentado cambios durante la pandemia. La investigación parte de un trabajo de campo y un cuestionario del balneario de Archena (Murcia) a 1406 clientes. Los resultados demuestran que los participantes tienen nuevas necesidades y prefieren como destinos vacacionales los balnearios, para pernoctar y recibir tratamientos de salud. No obstante, el grado de incertidumbre económica de muchos de ellos se ha visto incrementado exponencialmente y, aunque las medidas de seguridad en el establecimiento son importantes, la mayoría no están dispuestos a asumir costes económicos extra. Esta realidad puede orientar a los establecimientos termales para redirigir rápida y estratégicamente su oferta a una demanda con nuevas necesidades derivadas de la pandemia. Además, supone una oportunidad para los balnearios de posicionarse como una modalidad turística estratégica en la crisis sanitaria.
Konsep Perencanaan, Rekrutmen, dan Pengangkatan Sumber Daya Manusia di Madrasah Ibtidaiyah Al-Muthohhar Purwakarta
Authors: Huda Nenden Najiatul
Published: June 2022

Sumber Daya Manusia (SDM) merupakan komponen utama dan sebagai penentu keberhasilan dan kegagalan dalam suatu organisasi atau lembaga pendidikan. Kegiatan SDM yang akan dikelola dan dikembangkan dapat meningkatkan efektivitas dna efisiensi lembaga maupun bagi pendidik dan tenaga kependidikan, sehingga dapat diintegrasikan dengan tujuan perencanaan jangka pendek dan jangka panjang lembaga pendidikan, maka dari itu, penelitian bertujuan untuk mengetahui konsep perencanaan, perekrutan, dan pengangkatan guru di MI Al-Muthohhar. Metode yang digunakan dalam penelitianini adalah metode kualitatif, dimana lebih mementingkan segi proses daripada hasil. Adapun jenis penelitian ini adalah deskriptif analisis yaitu jenis penelitian yang mendeskripsikan secara jelas masalah penelitian dalam pembahasan dan kesimpulan. Hasil analisi data mendeskripsikan bahwa terdapat 3 poin penting yaitu tentang proses perencanaan guru, perekrutan, dan proses pengangkatan. Ketiga poin tersebut jika dijalankan dengan sebaik mungkin maka akan terciptanya pendidikan yang diharapkan, efektif, dan efisien.