bluuebunny/crossref_metadata_2025 huggingface dataset:
Carbon Footprint Status, Climate Change Mitigation Awareness and Education for Sustainable Development Perceptions of School Principals in the Island of Panay: Bases for an Eco-school Toolkit
Authors: Jimlan Ju-im T.
Published: April 2021

The study aimed to develop an eco-school toolkit based on the assessed levels of carbon footprint status, climate change mitigation awareness and education for sustainable development perceptions of principals in the Island of Panay for the School Year 2019-2020.  The researcher employed mixed method research design: quantitative and qualitative approach. A survey was conducted to the randomly selected 210 samples using the researcher-made questionnaires, and two sessions of focus group discussions were conducted to the Philippine - Open Government Partnership (P-OGP), National Executive Coordinating Council (NECC) and international philanthropists.  The Eco-School Toolkit was adopted from the 4Ds Training Cycle Map Process by Samuel Phil (2010).  The data was statistically interpreted through frequency counts, percentage, mean, standard deviation, Analysis of Variance, Pearson correlation coefficient at 0.05 level of significance.  The results shows that RPMS-PPST rating revealed that principals with “outstanding” and “very satisfactory” ratings consume maximum energy and living a “carbon-unfriendly lifestyle” resulting to an increase in the carbon footprint status. This may create negative impressions among teachers that “outstanding” or “very satisfactory” principals are not manifesting carbon friendly habits, attitudes, practices and cultures. On the other hand, geographical location, age, sexual orientation and RPMS PPST Rating will not affect climate change mitigation awareness of principals. Further, geographical location, age, sexual orientation and RPMS PPST Rating will not affect education for sustainable development perceptions of principals.  Carbon footprint status is a significant indicator of education for sustainable development. Climate change mitigation awareness is a significant indicator of education for sustainable development. The school principals’ carbon footprint status influences their climate change mitigation awareness and the climate change mitigation awareness influences their education for sustainable development perceptions; and education for sustainable development perceptions influences their carbon footprint status. The interconnectedness, interrelationships and interrelatedness of carbon footprint status, climate change mitigation awareness and education for sustainable development perceptions may create ecological foundations for school principals to be eco-friendly leader, serving an eco-friendly school and promoting an eco-friendly community for an eco-friendly nation.
Effect of Work Discipline and Compensation on the Performance of Employees of Subang District Trade and Industrial Cooperative Office
Authors: Juheti Ai , Sulaeman Eman
Published: April 2021

During the 2019-2024 government, President Joko Widodo made human resource development the focus of his second term government. So that the government continues to optimize the bureaucratic performance of the state civil apparatus both at the center and the region. One of the local government agencies, especially in Subang Regency, which is required to optimize bureaucratic performance is the Subang Regency Trade and Industry MSME Cooperative Office. This study uses a descriptive and verification research method with a quantitative approach. The population is employees of the Cooperative Office of MSME Trade and Industry Subang Regency. Sampled as many as 98 employees sample technique using the method of probability sampling a type of simple random sampling. Data collection techniques are conducted by observation, interviews and questionnaires. The results showed that partially work discipline affected employee performance by 23.4%. Compensation has an effect of employee performance by 14.6%. Furthermore, simultaneously work discipline and compensation have an effect on 38% of employee performance.
Communicative-Associative Transition to Smart Artificial Intelligence by Criteria with Help of Ensembles of Diversified Agents
Authors: Bryndin Evgeniy , Bryndina Irina
Published: April 2021

Cognitive virtual smart artificial intelligence can be formed by ensembles of diversified agents with strong artificial intelligence based on communicative-associative logic by recurring development of professional skills, increasing visual, sound, and subject, spatial and temporal sensitivity. Several diversifiable agents that try to get the same conclusion will give a more accurate result, so several diversifiable agents are combined into an ensemble. Then, based on the criteria of utility and preference, the final result is obtained based on the conclusions of diversifying agents. This approach increases accuracy. Bagging and boosting techniques are used to form ensembles. Bagging is a combination of independent diversifiable agents by averaging patterns (weighted average, majority vote, or normal average). Boosting is the construction of ensembles of diversifiable agents consistently. The idea here is that the next agent will consider the errors of the previous agent. Due to the fact that diversifiable agents take into account errors committed by previous agents, it takes less time to get to a real response. The combination of Bagging and Boosting decision-making methods allows the development of intelligent artificial intelligence by ensembles of diversified agents. Cognitive virtual smart artificial intelligence becomes smarter through the accumulated professional experience of high-tech skills, competencies and knowledge, having increased visual, sound, subject, spatial and temporal sensitivity. Standardization of strong artificial intelligence and the use of ensembles of intelligent compatible diversified agents will help to find boundaries in which smart artificial intelligence will benefit humanity and not harm.
Priapism in Patients Chronic Myeloid Leukemia
Authors: Gani Azhari , Jailani Muhammad
Published: April 2021

The aims of this study are to find out the healing process of Priapism in Patients Chronic Myeloid Leukemia. This study used one case of patient which has some complaint, The patients is man with age 29 years old, The patient complained of an enlarged left stomach since 4 months and became heavy in the last 2 weeks, On vital sign examination, compos mentis awareness was found with blood pressure 110/70 mmHg, pulse 80 times per minute, respiratory rate 20 times per minute and temperature 37oC. On the visual analogue scale (VAS) examination showed a value of 4-6 (moderate pain). The result shows that CML is a hematological malignancy characterized by the Philadelphia chromosome and detected clonal expansion of hematopoietic stem cells from ABL BCR examination on chromosomes 9 and 22 which is characterized by an increase in the number of leukocytes with or without enlargement of the spleen. One of the complications of CML is priapism which occurs due to hyperleukocytosis which causes an increase in the viscosity of the blood and this is a major cause of complications of vascular obstruction. Priapism in CML is classified as low-flow (static / ischemic) caused by venocclusiveness which must be treated immediately to restore blood flow to the cavernous corpora by means of needle aspiration.
Spectrum of adrenal disorders in a referral hospital of Bangladesh
Authors: Hossain Kazi Nazmul , Ashrafuzzaman SM , Pathan Md Faruque , Amin Md Feroz , Shefin Sultana Marufa , Afsana Faria , Rouf Rushda Sharmin Binte
Published: April 2021

Background: Adrenal diseases are common and their presentations are variable. This study aimed to determine the frequency and presenting features of various adrenal diseases in a tertiary care hospital of Bangladesh.

Methods: This retrospective descriptive study was carried out in Endocrinology in-patient department of BIRDEM General Hospital, Dhaka, Bangladesh, from October 2017 to December 2018. During this time, total 745 patients were screened; out of whom 91 had adrenal diseases.

Results: Mean age of the study population was 39.6±11.5 years. Among them, 65.9% were male. Most (75.8%) cases had adrenal insufficiency, followed by endogenous Cushing’s syndrome (8.8%), Conn’s syndrome (6.6%), non-functioning adenoma (3.3%), congenital adrenal hyperplasia (CAH) (2.2%), pheochromocytoma (1%), myelolipoma (1%) and adrenal carcinoma (1%). According to functional status, most (75.8%) were hypofunctional. Of the patients with adrenal insufficiency, secondary adrenal insufficiency was the most common (78.3%). Among the secondary adrenal insufficiencies, 75.9% had iatrogenic adrenal insufficiency and 24.1% had pituitary diseases. Regarding the cases of primary adrenal insufficiency, 20% cases were due to adrenal tuberculosis, 6.6% were due to adrenal histoplasmosis and 73.3% were idiopathic. Most of the adrenal insufficiency patients presented with hypotension (66.7%), followed by gastrointestinal symptoms (76.8%), weight loss (55.1%), hyponatraemia (42%), pigmentation (13%) and hypoglycemia (10%). In this study, 9.9% patients had adrenal incidentaloma. Most of them (88.9%) were benign. Causes of Cushing’s syndrome among the study population were, iatrogenic (66.7%), adrenal (16.7%) and pituitary cause (16.7%). In this study, 16.5% patients had endocrine hypertension and the causes were endogenous Cushing’s syndrome (53.3%), Conn’s syndrome (40%) and pheochromocytoma (6.7%). Of the hypertensive patients, 60% had co-existing hypokalemia.

Conclusion: Adrenal insufficiency was the most common adrenal disorder followed by endogenous Cushing’s syndrome, Conn’s syndrome, non-functioning adenoma and other adrenal disorders. Presentations of adrenal disorders are variable. Among the cause of adrenal insufficiency iatrogenic adrenal insufficiency was the most common.

Birdem Med J 2021; 11(2): 103-107
Microbiological profile and treatment outcome of emphysematous pyelonephritis: experience from two teaching hospitals of Bangladesh
Authors: Chowdhury Juli , Biswas Nirmol Kumar , Kanta Shamima Sharmin , Rahim Muhammad Abdur , Haque Wasim Md Mohosin Ul , Iqbal Sarwar , Uddin Khawja Nazim
Published: April 2021

Background: Emphysematous pyelonephritis (EPN) is a rare severe necrotizing infection of the renal parenchyma, collecting system and/or perirenal tissues. Patients with diabetes mellitus, renal stones and renal tract obstruction are at risk for development of EPN. Escherichia coli is the most common aetiological agent and treatment is aimed at infection control and interventions in appropriate cases. This study aimed to identify the aetiological agents responsible for EPN and the outcome of such cases.

Methods: This observational study was done in BIRDEM General Hospital and Bangabandhu Sheikh Mujib Medical University over a period of three years (2011-2013). Twenty adult EPN cases were included in this study.

Results: The mean age of the study participants was 59.2 years with female predominance (80%). Risk factors included diabetes mellitus (90%), renal stones (5%) and kidney transplant recipient (5%). Fever, loin pain and dysuria were common. Six patients had class 1 EPN, seven had class 2 disease, five had class 3 and two patients had class 4 EPN. Aetiological agents were cultured in 19 cases; E. coli in 12 (68%), Klebsiella in three (16%), Pseudomonus in two (11%) and Proteus and Enterococcus, one each (5% each). Carbapenems appeared as the most sensitive antibiotic. Along with antibiotic, half of the patients required interventions; percutaneous drainage in two, open drainage in two and six patients required nephrectomy. Regarding outcome, five patients died, 10 patients recovered completely and five patients recovered with residual renal dysfunction.

Conclusion: E. coli was the most common causative agent in present EPN cohort. Outcome was poor. With improved management strategy, combining nephrologists, intervention radiologists and urologists – all together, a good outcome is expected.

Birdem Med J 2021; 11(2): 108-111
Serum complement levels as prognostic marker for monitoring treatment response in lupus nephritis
Authors: Khan Saiful Bahar , Islam Rafi Nazrul , Mizan Md Saif Bin , Rahman AKM Shahidur , Hossain Shah Md Zakir , Mullah Shahida , Md Ershad Sk , Rahman Tanvir , Rahman Md Mustafizur , Feroz Salahuddin , Mohammad Kaiser Amir
Published: April 2021

Background: Lupus nephritis (LN) is one of the most common and serious manifestations of systemic lupus erythematosus (SLE) that causes significant morbidity and mortality. Certain biomarkers for LN are sometimes able to assess treatment response in lupus nephritis. This study aimed to compare serum complement levels (C3 and C4) as markers of treatment response of LN and their relation to the LN class in renal biopsy.

Methods: This prospective observational study was conducted in the Department of Nephrology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2018 to August 2019. Twenty seven patients who were diagnosed with LN after kidney biopsy were included in this study. Serum complement levels (C3 and C4), 24 hours urinary total protein (24-hr UTP) and anti-double-stranded DNA (anti-ds DNA) were measured in all patients at baseline, 3 months and 6 months after treatment initiation. These biomarker values before and after treatment were compared between the proliferative and non-proliferative LN patients.

Results: Serum C3 levels were significantly different between patients with proliferative LN (Class III and Class IV) and non-proliferative LN (Class V) at baseline (0.47 ± 0.32 g/l versus 0.89 ± 0.43 g/l, p=0.009) and levels changed significantly 6 months after treatment initiation (p<0.001) and likewise for serum C4 levels (0.10 ± 0.06 g/l versus 0.24 ± 0.26 g/l, p=0.040). The values of 24-hr UTP and anti-ds-DNA were significantly different 6 months after treatment with p value <0.05 in both groups but C3 (p<0.001) and renal Systemic Lupus Erythematosus Disease Activity Index (rSLEDAI) (p<0.001) were only significant in the proliferative group. On the other hand, after 6 months treatment, C4 levels became relatively higher but that was not significant in both groups (p>0.05).

Conclusion: After 6 months of treatment, serum C3 and C4 levels increased towards normal in both LN groups. Serum C3 and C4 levels in patients with LN correlate with disease activity. Therefore, serum complement (C3 and C4) levels may be utilized as serological biomarkers for treatment response of LN.

Birdem Med J 2021; 11(2): 97-102
Primary intraosseous meningioma: a case report
Authors: Taher MA , Mohammad Behnom Ishtiaque , Saha Mohua , Sultana Jafreen , Hossain Tasneem
Published: April 2021

Primary intraosseous meningioma (PIM) is a rare form of meningioma, a benign lesion of the meninges. Imaging evaluation of a patient with frontoparietal scalp swelling revealed an osteoblastic intracalvarial lesion. Following surgical resection, the histological examination revealed an intra-osseous meningioma.

Birdem Med J 2021; 11(2): 133-136
Nintedanib in the management of pulmonary fibrosis after COVID-19: a case report
Authors: Chakrabortty Rajashish , Rahman Samia , Jahan Rawnak , Dip Abir Hasan , Rahman Mohammed Mirazur
Published: April 2021

Pulmonary fibrosis is becoming a recognized complication of coronavirus disease 2019 (COVID-19). Patients with pulmonary fibrosis may present with dry cough, shortness of breath, nail clubbing, low oxygen saturation. We report a case of a 40-year-old male patient with pulmonary fibrosis due to COVID- 19. Clinical examination showed that the patient was dyspneic with low oxygen saturation and there was bilateral inspiratory crepitation in the lower part of his chest. High resolution computed tomography showed bilateral multifocal patchy ground-glass opacities, consolidation with peripheral and basal distribution, sub-pleural fibrotic bands and vascular thickening (almost 40-45% of parenchymal involvement). We prescribed him an antifibrotic drug, nintedanib and there was a significant clinical and radiological improvement after 15 days of treatment. Nintedanib may have novel therapeutic role in preventing COVID-19 associated fibrosis.

Birdem Med J 2021; 11(2): 148-152
«THE OUN MEMBER» VARVARA ZHURBENKO: THE FATE OF A REPRESSED TEACHER (BASED ON ARCHIVAL-CRIMINAL CASE FILE)
Authors: HALIV Mykola , OНAR Anna
Published: April 2021

The article reveals Varvara Stepanіvna Zhurbenko's biography. In 1946, the Soviet state security authorities accused her of being a «parricide» and a member of the Organization of Ukrainian Nationalists (OUN). The article's relevance is due to the need to determine whether V. Zhurbenko was an OUN member. The article also illustrates the illegal mechanisms used by the Soviet repressive authorities. The research's main source was the V. Zhurbenko's archival-criminal case, which is stored in the Archive of the Security Service of Ukraine in the Lviv region. As a result of the study, it was found that V. Zhurbenko participated in the activities of one of the OUN grassroots units in Dnipropetrovsk in early 1943. She did not join the OUN, but her contacts with OUN's member N. Voronina, who was also an agent of Soviet special services, played a tragic role in her later life. Having received a pedagogical education, V. Zhurbenko worked in the incomplete secondary school of the village Khidnovychi in the Drohobych region. In late 1944 – early 1945, she corresponded with N. Voronina. She was arrested in October 1946. During the investigation, V. Zhurbenko was forced to confess to belonging to the OUN. She was sentenced to 10 years in prison in the Soviet concentration camps. After J. Stalin's death, when the totalitarian regime weakened somewhat, V. Zhurbenko tried to achieve justice. As a result, her case was double-checked (in 1955 and 1959), and eventually, V. Zhurbenko was rehabilitated. She was able to prove that the criminal case against her had been fabricated by an MGB investigator who had used the beating and threats. Thus, the authors found out that V. Zhurbenko was not a member of the OUN, although some contemporary historians were convinced that she belonged to this organization.

Keywords: Varvara Zhurbenko, MGB, OUN, Dnipropetrovsk, Drohobych region, military tribunal, rehabilitation.
HISTORY OF LITERATURE OR PHILOLOGICAL STUDIES: TEXTBOOKS OF UKRAINIAN LITERATURE IN THE 19TH CENTURY IN THE UNIVERSITY SYSTEM
Authors: HENTS Adriana
Published: April 2021

The article explores the theoretical and practical principles of Ukrainian
literature histories in the context of pan-European historiographical traditions.
The study's subject is histories of literature, which are an integral part of Western scientific thought
and hold an important place in the history of national and European university
literary studies of the nineteenth century are outlined, the histories of
education. The stages of the development of the literary history of the world
Ukrainian literature are analyzed and systematized in typological comparisons
characteristics, criteria for selecting texts, author's interpretations,
with European concepts. The difference between the historiographical studies of
literature and the textbooks, which is primarily reflected in formal
conceptual approaches, and methodological base, is revealed. The basis of
and interdependence. The genealogical and genre features of Ukrainian literary
historiographical studies is the identification of the intrinsic connection
between literary history, philosophy, and history, the study of their interdependence
studies are considered. The author pays attention to the methodological planes
realities. The advantages and disadvantages of literary histories, reviews, and
and vectors of the study of historiographical discourse. The article describes
the main achievements of historians of the literature of the 19th century,
comprehensively defines the methodology of creating an integrated and scientific evidence corpus of Ukrainian literature history in contemporary
of university literary education and the creation of a pan-European cultural
holistic syntheses of Ya. Holovatskyi, P. Kulish, M. Petrov, M. Dashkevych, I.
Franko are analyzed not only in the paradigm of Ukrainian literary
historiography but also in the process of integration of Ukraine into the worldeducational space.
The historiography has great importance in the development
discourse.
Keywords: history of literature, historiography, history of ideas, textbooks, methodology of literary studies, university education.
Nomenclaturas, terminologias e classificação das startups: Uma revisão multivocal da literatura
Authors: Gonçalves Kelly Lima Fonseca , Gonçalves Rodrigo Franco
Published: April 2021

A ausência de uma nomenclatura, terminologia e classificação referentes ao universo das startups pode levar à inconsistências nas pesquisas acadêmicas. O objetivo deste artigo é sistematizar a nomenclatura e a terminologia do universo das startups e estabelecer uma taxonomia destas, bem como sua classificação considerando o ponto de vista acadêmico e de mercado. Além disso, propor termos únicos para uso da academia. O estudo utilizou uma Revisão Multivocal da Literatura sobre startups verificando as nomenclaturas, terminologias e classificações que a norteiam (fases, público-alvo, modelo de negócio), tanto na literatura acadêmica, como na literatura cinza. O resultado permitiu a apresentação das informações de maneira a comparar as diversas bases existentes sobre o tema. O estudo utilizou parâmetros próprios e quatro fontes de dados, o que representa uma oportunidade para estudos futuros sobre o assunto, explorando outras fontes de dados e metodologias de pesquisa. Além disso, o termo “startup” é um verbo muito utilizado na língua inglesa o que causa muito equívoco com o que se denominou “startup” nesse artigo. O estudo visa contribuir com um modelo de nomenclatura padrão a fim de alcançar uma análise eficiente da linguagem empresarial das startups com o propósito de auxiliar pesquisadores e empreendedores envolvidos. As definições propostas constituem uma terminologia de referência com apresentação de conceitos dos termos de startups, conciliando a terminologia acadêmica com a utilizada no mercado quanto a target public, income model and stage.
Desenvolvimento e validação de uma cartilha fundamentada no letramento em saúde sobre chás medicinais para mulheres sobreviventes de câncer de mama
Authors: Rodrigues Maria Lucila Magalhães , Ponte Tereza Doralucia Rodrigues , Vasconcelos Cláudia Machado Coelho Souza de , Cacau Leandro Teixeira , Sampaio Helena Alves de Carvalho
Published: April 2021

Objetivo: Descrever o processo de construção e validação de uma cartilha sobre chás com propriedades medicinais, destinada a mulheres sobreviventes de câncer de mama, elaborada segundo os fundamentos do letramento em saúde. Método: Estudo metodológico realizado em três etapas: 1) entrevista com mulheres sobreviventes de câncer de mama para identificação dos chás mais utilizados por elas; 2) desenvolvimento da cartilha e 3) validação da cartilha por especialistas e público-alvo. A partir das informações das 203 mulheres entrevistadas, foram selecionadas cinco plantas para integrar a cartilha: Graviola (folha), Camomila, Hortelã, Gengibre e Romã. O conteúdo da cartilha foi desenvolvido segundo o conhecimento científico sobre o tema e orientações de publicações específicas sobre letramento em saúde, com o intuito de viabilizar maior empoderamento das informações por parte das mulheres. A validação foi realizada por seis especialistas, os quais usaram o instrumento Suitability Assessment of Material (SAM), destinado à avaliação de materiais escritos de acordo com os fundamentos do letramento em saúde. A validação pelo público-alvo se deu por grupo focal. Resultados: Os especialistas atribuíram à cartilha pontuação percentual média de 91,4%, o que a enquadra como material superior quanto ao letramento em saúde (70-100%). O público-alvo aprovou a cartilha, sem sugestão de mudanças. Conclusão: A cartilha está validada e atende aos fundamentos do letramento em saúde, podendo ser utilizada nos atendimentos realizados com mulheres sobreviventes de câncer de mama como um material educativo auxiliar em seu tratamento.
Atividades experimentais investigativas e a habilidade de elaborar hipóteses na formação inicial de professores
Authors: Frazão Lucenir da Silva , Gusmão Marta Silva dos Santos , Antunes Ettore Paredes
Published: April 2021

Neste trabalho buscamos identificar as contribuições das atividades experimentais investigativas para o desenvolvimento da habilidade científica de projetar um experimento para testar uma hipótese durante a formação inicial de discentes de Licenciatura em Física e em Química. Realizamos uma pesquisa qualitativa com 20 participantes de cursos de uma Universidade Federal no Norte do Brasil. Por intermédio de uma oficina com experimentação investigativa no laboratório, os discentes elaboraram suas hipóteses e realizaram os experimentos para testá-las. Os dados foram coletados por meio de atividades escritas realizadas e entrevistas, as quais foram analisadas, respectivamente, por rubricas e pela Análise Textual Discursiva. Constatamos que as atividades experimentais investigativas são uma alternativa promissora para desenvolver a habilidade de elaborar hipótese, porém a pesquisa mostra que essa habilidade necessita ser trabalhada em atividades com maior tempo de duração.
Tendência temporal, aglomerado espacial de risco e vulnerabilidade social da prevalência de quedas entre idosos em uma área do Nordeste do Brasil (2008-2015): um estudo ecológico
Authors: Araújo Damião da Conceição , Santos Allan Dantas dos , Lima Shirley Veronica Melo Almeida , Vaez Andreia Centenaro , Araújo Karina Conceição Gomes Machado de
Published: April 2021

Objetivo: analisar a tendência temporal, os aglomerados espaciais de risco e associação com a vulnerabilidade social na prevalência de quedas entre idosos no estado de Sergipe, Nordeste do Brasil. Metodologia: Estudo ecológico, exploratório e analítico realizado no estado de Sergipe, Nordeste do Brasil. Os dados foram coletados no Sistema Nacional de Notificação de Doenças do Brasil, Instituto Brasileiro de Geografia e Estatística e Programa das Nações Unidas para o Desenvolvimento. Foi conduzida uma análise temporal e espacial da prevalência de quedas entre idosos e a associação com indicadores de vulnerabilidade social. Resultados: No período de 2008 a 2015 foram notificados 273 casos de quedas entre idosos no estado de Sergipe. A prevalência do período analisado foi de 15,6% apresentado tendência decrescente no período de 2008 a 2013 e crescente em 2013 a 2015. A análise espacial identificou um aglomerado de risco na região oeste do estado. Os indicadores que apresentaram associação com a prevalência de quedas foram relacionados a renda, escolaridade, envelhecimento e pobreza. Conclusão: As técnicas espaciais e temporais definiram as áreas de risco para quedas entres idosos, bem como a identificação dos fatores de vulnerabilidade social associados.
Grupo estratégico de promoção da saúde como dispositivo de cuidado a pessoas que vivem com diabetes mellitus
Authors: Araújo Juliana Iscarlaty Freire de , Medeiros Marília Rute de Souto , Souza Talita Araújo de , Silva Ilisdayne Thallita Soares da , Silva José Adailton da
Published: April 2021

Este estudo tem por objetivo analisar as experiências dos sujeitos que convivem com diabetes e que participaram de um grupo com estratégias delimitadas, em relação ao controle da doença e exercício da autonomia pessoal. Trata-se de um estudo do tipo participativo, com abordagem qualitativa, apoiada na reflexibilidade, onde os encontros realizados deram origem a narrativas que foram organizadas em eixos temáticos e analisados. O trabalho mostrou que o grupo assume uma característica de rede de apoio, e agente facilitador para o convívio com a síndrome, onde a premissa da troca de vivências contribui significativamente no processo de transformação do outro, refletindo no processo de co-construção da autonomia pessoal, e por consequência melhora da qualidade d vida dos sujeitos envolvidos. Pode-se concluir que as práticas grupais como dispositivo de promoção da saúde, possibilitam um impacto positivo na qualidade de vida das pessoas, desenvolvimento da autonomia e autocuidado.
Cirurgia e Traumatologia Bucomaxilofacial em tempos de pandemia de COVID-19: Gestão, riscos e perspectivas
Authors: Santos Daniela Meneses , Oliveira Mirlany Mendes Maciel , Lauand Gustavo Amaral , Silva Cláudia Jordão , Silva Marcelo Caetano Parreira da , Batista Jonas Dantas
Published: April 2021

A síndrome respiratória aguda grave (SARS-CoV-2) é uma doença respiratória infecciosa com taxas de morbidade e mortalidade significativas evoluindo no ano de 2020 como uma Pandemia. A odontologia é classificada na categoria de alto risco devido a maioria dos procedimentos gerarem aerossóis e a Cirurgia oral e maxilofacial é a especialidade odontológica que desempenhando funções tanto no âmbito hospitalar quanto no âmbito ambulatorial.   O objetivo do presente trabalho é fazer um análise da gestão, riscos e perspectivas da cirurgia oral e oral e cirurgia maxilofacial em tempos de pandemia de COVID-19, visto que as cirurgias eletivas devem ser suspensas e as urgências priorizadas com o principal objetivo do gerenciamento dos risco para evitar o contágio em cuidado de emergência porém, quanto as pespectivas futuras é imprescindivel a adaptação desses profissionais a nova realidade de atendimento em virtude de diversas procedimentos realizados serem de caracter de urgência e emergência.
Preoperative use of gabapentin for pain reduction in open surgeries under local anesthesia for idiopathic bilateral carpal tunnel syndrome
Authors: Georgeto Sergio Murilo , Andraus Rodrigo Antônio Carvalho , Pires Ovídia Ignês , Oliveira Junior Eros de , Fernandes Karen Barros Parron
Published: April 2021

This article aims to evaluate the preoperative use of gabapentin in the control of intra- and postoperative pain in patients with idiopathic bilateral carpal tunnel syndrome (CTS). A prospective, randomised, double-blind study involving 45 subjects with severe CTS, 23 receiving treatment (gabapentin 600 mg) and 22 receiving placebo (control), who underwent an open surgical approach in one hand under local anaesthesia. Information related to the patients’ profile, safety of the surgical procedure, history of pain, adverse effects, numbness, and medications used were collected during the 14 days of the procedure and evaluated by Generalised Estimated Equations and Generalised Linear Mixed Models. The treatment and control groups were homogeneous regarding the patients’ profile and surgical procedure data. The patients who used gabapentin 600 mg had a better evaluation during surgery (d = 0.655), anaesthesia (d = 0.854), and on the first night of sleep (d = 1.323), and they reported a higher degree of satisfaction with the surgery after 14 days (d = 1.091). The treatment group reported decreased pain in the operated hand in a 24-hour period (r = 0.34, 95% CI: 0.223–0.457) and in the 14-day follow-up period (r = 0.412, 95% CI: 0.217–0.608). These results were not impacted by the medications used and remained consistent over time. The use of a single dose of gabapentin 600 mg in the preoperative period proved to be safe and effective in reducing postoperative pain, and the improvement was noticed by the patient.
Effects of micronized-roasted coffee concentration and temperature process on technological properties of rice-based extruded
Authors: Sampaio Ulliana Marques , Campelo Pedro , Chang Yoon Kil , Clerici Maria Teresa Pedrosa Silva
Published: April 2021

New ingredients have been used in extruded products to increase the healthiness and regionalization of these products. However, the process variables that can interfere with the technological quality of the product should be studied, aimed at good acceptance by consumers. This study aimed to evaluate the effects of the concentration of micronized roasted coffee (MRC) and the barrel temperature on the technological properties of rice-based extrudates. The extrudates were made with 3 and 8% MRC to replace rice flour and processed in a mono-extruder at 140 and 180 oC. They were characterized for color, expansion index, hardness, bowl-life, porosity, water absorption index, and solubility index, and paste properties. To assess the effects of the process variables, analysis of variance, and Scott-Knott test (p <0.05) were applied to compare the means. The increase in MRC concentration reduced the color parameters and hardness, while the increase in temperature affected the expansion index. A joint effect of the variables concentration and temperature was observed for the other properties evaluated. The study showed that MRC is a potential source of fibers and natural pigments, with a direct effect on the main technological properties of the final product.
University of Miami Laboratory for Integrative Knowledge (U-LINK) Program Evaluation Report
Authors: Morgan Susan , Mosser Alexandra , Bixby John
Published: April 2021

As one of the Roadmap Initiatives, U-LINK (University of Miami Laboratory for INtegrative Knowledge) is the University of Miami’s (UM’s) program to support innovative, problem-based interdisciplinary research. The U-LINK initiative is premised on the idea that the most significant challenges facing humanity, and therefore the most important research problems, require innovative and integrative approaches resulting from collaborations that bridge disciplines. The goal of U-LINK is to bring together faculty and trainees from multiple disciplines in collaboration with community stakeholders to develop and act on a shared vision of innovative solutions to grand societal challenges. To accomplish this goal, U-LINK provides training and funding opportunities for research teams, identifies common space(s) for teams to work together, creates interdisciplinary opportunities for UM undergraduate and graduate students, and helps UM faculty identify and pursue collaborative initiatives with faculty in other departments, schools, and colleges. This document details the features of the U-LINK program and provides data about outcomes of the program through 2019.
Effective Communication in English: Preparing Undergraduate Students in the United States-Mexico Border
Authors: Díaz Eduardo R
Published: April 2021

The aim of this study was to examine the perspectives of 15 undergraduate students in terms of their choice of an academic program. The approach of this study was conducted through the qualitative case study. The results suggest that participants believe that improving their communication skills in English will facilitate their integration into the economy of the United States-Mexico border region. The novelty of this finding is that it prioritizes English as a second language for undergraduate students, perhaps at the level of discipline-specific program characteristics. The main limitation of this study was its focus on one side of the border.
PELATIHAN PEMBUATAN PUPUK KOMPOS DI PERUM. BUMI TUNGGULWULUNG INDAH KOTA MALANG
Authors: Sumiadji  , Futuh H  , Basuki R  , Endah S  , Edi W
Published: April 2021

Kegiatan PkM ini dilakukan untuk mengatasi permasalahan sampah yang dihadapi warga perum. Bumi Tunggulwulung Indah Lowokwaru Malang (BTWI) terutama berupa sampah daun dari pohon taman di perumahan. Terjadi penumpukan sampah dikarenakan sampah tidak secara rutin diangkut ke tempat penampungan sementara (TPS) dengan banyak sebab seperti faktor cuaca, tukang dan alat gerobak angkut atau kondisi volume sampah di TPS yang penuh. Khusus untuk sampah daun akan dibuat pupuk kompos kemudian dikemas dan dijual. Metode yang diterapkan dalam kegiatan PKM adalah penyuluhan, pelatihan dan pemantauan (monitoring). Penyuluhan pemberian materi teoritis tentang cara-cara pengelolaan dan pengolahan sampah. Pelatihan sebagai bentuk implementasi praktis dengan membuat pupuk kompos yang benar, efektif dan efisien sehungga memiliki nilai ekonomis. Pada tahap akhir dilakukan pemantauan hasil kegiatan pengabdian kepada masyarakat. Hasil kegiatan PkM menjadi salah satu solusi mengatasi masalah sampah menjadi produk bernilai ekonomis.
PEMBUATAN BIOPORI UNTUK PENYERAPAN AIR VERTIKAL DAN PEMBUATAN PUPUK ORGANIK
Authors: Santoso  , Lisa Agustriana  , Maskuri  , Sudarmadji  , Syamsul Hadi
Published: April 2021

Adanya genangan air hujan, banjir di daerah yang rendah, kurangnya kemampuan selokan menyalurkan air hujan, dan meningkatnya volume sampah sebagai masalah yang dihadapi. Tujuan pengabdian untuk membantu masyarakat meningkatkan penyerapan air vertikal sebagai sarana mengurangi genangan air hujan, banjir di daerah yang rendah dan mengurangi volume air di selokan serta pembuatan pupuk organik sebagai sarana mengurangi volume sampah. Metoda yang diterapkan adalah musyawarah dengan warga dan kajian literatur untuk menentukan desain konstruksi biopori, penentuan kedalaman lubang, pembuatan bor tanah, pemotongan pipa PVC, pembuatan lubang pada pipa PVC dan tutupnya (pipa biopori) , proses pengeboran tanah pada tempat yang telah di sepakati, pemasangan pipa biopori, dan penyerahan hasil pembuatan biopori kepada ketua RT setempat. Hasil pembuatan biopori diharapkan dapat meningkatkan resapan hujan ke dalam tanah, sehingga dapat mengurangi terjadinya genangan air hujan, banjir, dan normalnya aliran air di selokan. Selanjutnya setiap warga diharapkan bersedia memisahkan sampah organiknya untuk dijadikan kompos di pipa biopori yang telah tersedia dan terjadi sinergi antara Polinema dan warga masyarakat dalam memperoleh peningkatan resapan air hujan dan pengurangan volume sampah rumah tangga di RT.09/RW.07 kelurahan Mojolangu-Lowokwaru-Malang yang berimplikasi penyadaran warga atas lingkungan bersih, sehat, dan tertata. Kesimpulan hasil pembuatan biopori sebagai sarana meningkatkan resapan air dan mengurangi volume sampah rumah tangga serta sebagai sarana pembuatan pupuk organik.
Förord
Authors: Dahlstedt Magnus , Gruber Sabine , Herz Marcus , Lalander Philip
Published: April 2021

Temanummer: Kritiska sociala arbeten
Möjligheter och svårigheter för kritisk forskning i socialt arbete
Authors: Mattsson Tina
Published: April 2021

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USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway
Authors: Zhu Suwei , Hou Shaoshuai , Lu Yao , Sheng Wei , Cui Zhengguo , Dong Tianyi , Feng Hong , Wan Qiang
Published: April 2021

Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease but the efficacy of current treatment remains unsatisfactory. The pathogenesis of DKD needs a more in-depth research. Ubiquitin specific proteases 36 (USP36), a member of deubiquitinating enzymes family, has aroused wide concerns for its role in deubiquitinating and stabilizing target proteins. Nevertheless, the role of USP36 in diabetes has never been reported yet. Herein, we identified an increased expression of USP36 both in vitro and in vivo in diabetic renal tubular epithelial cells (TECs), and its overexpression is related to the enhanced epithelial-to-mesenchymal transition (EMT). Further investigation into the mechanisms proved that USP36 could directly bind to and mediate the deubiquitination of dedicator of cytokinesis 4 (DOCK4), a guanine nucleotide exchange factor (GEF) that could activate Wnt/β-catenin signaling pathway and induce EMT. Our study revealed a new mechanism that USP36 participates in the pathogenesis of DKD, and provided potential intervening targets accordingly.
Combination of Immune-Related Genomic Alterations Reveals Immune Characterization and Prediction of Different Prognostic Risks in Ovarian Cancer
Authors: Zhao Xibo , Cong Shanshan , Guo Qiuyan , Cheng Yan , Liang Tian , Wang Jing , Zhang Guangmei
Published: April 2021

With the highest case-fatality rate among women, the molecular pathological alterations of ovarian cancer (OV) are complex, depending on the diversity of genomic alterations. Increasing evidence supports that immune infiltration in tumors is associated with prognosis. Therefore, we aim to assess infiltration in OV using multiple methods to capture genomic signatures regulating immune events to identify reliable predictions of different outcomes. A dataset of 309 ovarian serous cystadenocarcinoma patients with overall survival >90 days from The Cancer Genome Atlas (TCGA) was analyzed. Multiple estimations and clustering methods identified and verified two immune clusters with component differences. Functional analyses pointed out immune-related alterations underlying internal genomic variables potentially. After extracting immune genes from a public database, the LASSO Cox regression model with 10-fold cross-validation was used for selecting genes associated with overall survival rate significantly, and a risk score model was then constructed. Kaplan–Meier survival and Cox regression analyses among cohorts were performed systematically to evaluate prognostic efficiency among the risk score model and other clinical pathological parameters, establishing a predictive ability independently. Furthermore, this risk score model was compared among identified signatures in previous studies and applied to two external cohorts, showing better prediction performance and generalization ability, and also validated as robust in association with immune cell infiltration in bulk tissues. Besides, a transcription factor regulation network suggested upper regulatory mechanisms in OV. Our immune risk score model may provide gyneco-oncologists with predictive values for the prognosis and treatment management of patients with OV.
Carbapenem-Resistant Enterobacterales in Long-Term Care Facilities: A Global and Narrative Review
Authors: Chen Hsin-Yu , Jean Shio-Shin , Lee Yu-Lin , Lu Min-Chi , Ko Wen-Chien , Liu Po-Yu , Hsueh Po-Ren
Published: April 2021

The emergence of carbapenem-resistant Enterobacterales (CRE) has become a major public health concern. Moreover, its colonization among residents of long-term care facilities (LTCFs) is associated with subsequent infections and mortality. To further explore the various aspects concerning CRE in LTCFs, we conducted a literature review on CRE colonization and/or infections in long-term care facilities. The prevalence and incidence of CRE acquisition among residents of LTCFs, especially in California, central Italy, Spain, Japan, and Taiwan, were determined. There was a significant predominance of CRE in LTCFs, especially in high-acuity LTCFs with mechanical ventilation, and thus may serve as outbreak centers. The prevalence rate of CRE in LTCFs was significantly higher than that in acute care settings and the community, which indicated that LTCFs are a vital reservoir for CRE. The detailed species and genomic analyses of CRE among LTCFs reported that Klebsiella pneumoniae is the primary species in the LTCFs in the United States, Spain, and Taiwan. KPC-2-containing K. pneumoniae strains with sequence type 258 is the most common sequence type of KPC-producing K. pneumoniae in the LTCFs in the United States. IMP-11- and IMP-6-producing CRE were commonly reported among LTCFs in Japan. OXA-48 was the predominant carbapenemase among LTCFs in Spain. Multiple risk factors associated with the increased risk for CRE acquisition in LTCFs were found, such as comorbidities, immunosuppressive status, dependent functional status, usage of gastrointestinal devices or indwelling catheters, mechanical ventilation, prior antibiotic exposures, and previous culture reports. A high CRE acquisition rate and prolonged CRE carriage duration after colonization were found among residents in LTCFs. Moreover, the patients from LTCFs who were colonized or infected with CRE had poor clinical outcomes, with a mortality rate of up to 75% in infected patients. Infection prevention and control measures to reduce CRE in LTCFs is important, and could possibly be controlled via active surveillance, contact precautions, cohort staffing, daily chlorhexidine bathing, healthcare-worker education, and hand-hygiene adherence.
Mucociliary Clearance Scans Show Infants Undergoing Congenital Cardiac Surgery Have Poor Airway Clearance Function
Authors: Adams Phillip S. , Corcoran Timothy E. , Lin Jiuann-Huey , Weiner Daniel J. , Sanchez-de-Toledo Joan , Lo Cecilia W.
Published: April 2021

Background: Infants undergoing congenital cardiac surgery with cardiopulmonary bypass are at high risk for respiratory complications. As impaired airway mucociliary clearance (MCC) can potentially contribute to pulmonary morbidity, our study objective was to measure airway clearance in infants undergoing congenital cardiac surgery and examine correlation with clinical covariables that may impair airway clearance function.

Materials and Methods: Airway clearance in infants was measured over 30 min using inhaled nebulized Technetium 99m sulfur colloid administered either via a nasal cannula or the endotracheal tube in intubated infants. This was conducted bedside with a portable gamma camera. No difficulty was encountered in positioning the gamma camera over the patient, and neither the camera nor the MCC scan interfered with routine medical care or caused any adverse events. Patient and perioperative variables were examined relative to the MCC measurements.

Results: We prospectively enrolled 57 infants undergoing congenital cardiac surgery and conducted a single MCC scan per patient. MCC data from 42 patients were analyzable, including five pre-operative, 15 (40.5%) in the immediate post-operative period (days 1–2), and 22 (59.5%) were later post-operative (≥3 days). Pre-operative MCC was inversely proportional to days requiring post-operative mechanical ventilation (p = 0.006) and non-invasive positive pressure ventilation (p = 0.017). MCC was higher at later post-operative days (p = 0.002) with immediate post-operative MCC being lower (3%; 0–13%) than either pre-operative (21%; 4–25%) (p = 0.091) or later post-operative MCC (18%; 0–29%) (p = 0.054). Among the infants with low post-operative MCC, significantly more were pre-mature [5/19 (26%) vs. 0/18 (0%); p = 0.046], were intubated [14/19 (75%) vs. only 7/18 (39%); p = 0.033] and were receiving higher FiO2 (40%, 27–47% vs. 26%, 21–37%; p = 0.015).

Conclusions: This is the first study to show that infants undergoing congenital cardiac surgery have impaired MCC. MCC appeared lowest in the immediate post-operative period. Worse MCC was associated with pre-maturity, mechanical ventilation, or receiving higher FiO2. These findings suggest MCC scans should be further explored for informing clinical decision making to improve post-surgical respiratory outcomes. The possible therapeutic benefit of airway clearance maneuvers for infants with poor MCC function should also be investigated.