bluuebunny/crossref_metadata_2025 huggingface dataset:
Enzymatic activities and analysis of a mycelium-based composite formation using peach palm (Bactris gasipaes) residues on Lentinula edodes
Authors: de Lima Gabriel , Schoenherr Zaira , Magalhães Washington , Tavares Lorena , Helm Cristiane
Published: October 2020

By seeding fungus on top of industry residues, a mycelium can grow and form a compact network structure; however, it may not develop due to lack of optimal nutrients from the substrate. Consequently, peach palm residues can be a potential alternative; so, to test this hypothesis, this work evaluates the effect of peach palm residues as substrate for the growth of mycelium based on Lentinula edodes . They were also supplemented with cassava bran and various sources of nitrogen – ammonium sulphate, potassium nitrate and soy flour – in order to analyse its effects on its physico-chemical, enzymatic activities and thermal and mechanical properties of the final composite at 12 and 20 days of cultivation. This mycelium was able to grow at optimum source treatment conditions, that depends on the ratio of Carbon to Nitrogen, within only 12 days of inoculation. Furthermore, the enzyme activities directly correlate with the mycelium growth with optimum conditions of pH, water activity and moisture for L. edod es to grow having lower enzyme activities for a well-developed composite; whereas higher activities were seen for a weakly developed material. and this material demonstrate mechanical and thermal properties similar to common mycelium-based composites Therefore, this work demonstrates that peach palm residues can be a potential alternative for mycelium-based composite
External Validation Of The Surgical Outcome Risk Tool (sort) In 3305 Abdominal Surgery Patients In The Independent Sector In The United Kingdom
Authors: Oakland Kathryn , Cosentino Daria , Cross Timothy , Bucknall Cliff , Dorudi Sina , Walker David
Published: October 2020

Background

Assessing risk of post-surgical mortality is a key component of pre-surgical planning. The Surgical Outcome Risk Tool (SORT) uses pre-operative variables to predict 30-day mortality. The aim of this study was to externally validate SORT in patients undergoing major abdominal surgery.

Methods

Data were collected from patients treated in five Independent hospitals in the United Kingdom. Individualised SORT scores were calculated and area under the receiver operating characteristic (AUROC) and precision-recall curves (PRC) plus 95% confidence intervals (CI) were drawn to test the ability of SORT to identify in-hospital death. Outcomes of patients with a SORT predicted risk of mortality of ≥5% (high risk) were compared to those with a predicted risk of <5% (standard risk).

Results

The study population comprised 3305 patients, mean age 51 years, 2783 (84.2%) underwent elective surgery most frequently involving the colon (24.6%), or liver, pancreas or gallbladder (18.2%). Overall 1551 (46.9%) patients were admitted to ICU and 29 (0.88%) died. The AUROC of SORT for discriminating patients at risk of death was 0.899 (95% CI 0.849 to 0.949) and the PRC 0.247. In total 72 (2.18%) patients were stratified as high risk. There were more unplanned ICU admissions and deaths in this group compared to the standard risk group (25.0% and 3.3%, versus 3.1% and 0.5%, respectively).

Conclusion

We externally validated SORT in a large population of abdominal surgery patients. SORT performed well in patients with lower risk profiles, but some patients that were predicted to be standard risk did experience adverse outcomes.
Pattern of cortical thinning in logopenic progressive aphasia patients in Thailand
Authors: Thanprasertsuk Sekh , Likitjaroen Yuttachai
Published: October 2020

Background: Logopenic progressive aphasia (LPA) is an uncommon neurodegenerative disorder primarily characterized by word-finding difficulties and sentence repetition impairment. Prominent cortical atrophy around left temporo-parietal junction (TPJ) is a classical imaging feature of LPA. This study investigated cortical thinning pattern in clinically diagnosed LPA patients using non-demented subjects as a control group. We also aimed to explore whether there was prominent thinning of other cortical area additional to the well-recognized left TPJ.Methods: Thicknesses of all cortical regions were measured from brain magnetic resonance images using an automated command on Freesurfer software. Cortical thickness of the two groups were compared by two methods: 1) using a general linear model (GLM) in SPSS software; and 2) using a vertex-by-vertex GLM, performed with Freesurfer’s QDEC interface. Results: Besides the well-recognized left TPJ, cortical regions that were significantly thinner in the LPA group by both comparison methods included left caudal middle frontal gyri (CMFG) (p=0.006 by SPSS, p=0.0003 by QDEC), left rostral middle frontal gyrus (p=0.001 by SPSS, p=0.0001 by QDEC), left parahippocampal gyrus (p=0.008 by SPSS, p=0.005 by QDEC) and right CMFG (p=0.005 by SPSS, p=0.0001 by QDEC).Conclusions: Our results demonstrated that thinning of middle frontal gyri may be an additional feature in clinically diagnosed LPA patients. Involvement of left parahippocampal gyrus may reflect the underlying neuropathology of Alzheimer’s disease in majority of the LPA patients.
Identification of a novel subpopulation of Caspase-4 positive Non-Small Cell Lung Cancer patients.
Authors: Terlizzi Michela , Colarusso Chiara , De Rosa Ilaria , Somma Pasquale , Curcio Carlo , Aquino Rita , Panico Luigi , Salvi Rosario , Marino Federica Zito , Botti Gerardo , Pinto Aldo , Sorrentino Rosalinda
Published: October 2020

Background . Therapy/prognosis of Non-Small Cell Lung Cancer (NSCLC) patients are strongly related to gene alteration/s or protein expression. However, more than 50% of NSCLC patients are negative to key drugable biomarkers.
Methods: We used human samples of NSCLC and mouse models of lung adenocarcinoma.
Results . We showed that caspase-4 was highly present in the tumor mass compared to non-cancerous human tissues. Interestingly, the orthologue murine caspase-11 promoted lung carcinogenesis in mice. Carcinogen-exposed caspase-11 knockout mice had lower tumor lesions than wild type mice, due to the relevance of caspase-11 in the structural lung cell as demonstrated by bone marrow transplantation and adoptive transfer experiments. Similarly to what observed in mice, caspase-4 was correlated to the stage of lung cancer in humans in that it induced cell proliferation in a K-Ras, c-MyC and IL-1α dependent manner. Caspase-4 positive adenocarcinoma (79,3%) and squamous carcinoma (88.2%) patients had lower median survival than patients who had lower levels of caspase-4. Moreover, PD-L1 expression and gene mutation (i.e. EGFR) were not correlated to caspase-4 expression. Instead, NSCLC patients who had K-Ras or c-MyC gene alteration were positively correlated to higher levels of caspase-4 and lower survival rate. Conclusions . We identified a subgroup of NSCLC patients as caspase-4 positive among which double and triple positive caspase-4, K-Ras and/or c-MyC patients which prognosis was poor. Because K-Ras and c-MyC are still undrugable, the identification of caspase-4 as a novel oncoprotein could introduce novelty in the clinical yet unmet needs for NSCLC patients.
The effectiveness of household water treatment and safe storage in improving drinking water quality: a disinfection by-product (DBP) perspective
Authors: Xiao Rong , Duan Youli , Chu Wenhai
Published: October 2020

Serving as the last barrier to secure drinking water safety, household water treatment and safe storage (HWTS) is perceived as an interim measure for removing pathogens from drinking water and reducing disease risk. In recent years, the application of HWTS has shown a growing trend, and its performance in controlling chemicals has also received much attention. Disinfection by-products (DBPs) are formed by the reaction of chemical disinfectants and precursors, and are present at sub-μg·L−1 or low-to-mid-μg·L−1 levels in drinking water. Although precursor control and disinfection operation modification could contribute to DBP mitigation to some degree, DBP removal after their formation emerges as an important strategy due to the ubiquitous existence of DBPs in distribution systems and tap water. In order to figure out how DBP concentrations vary during the residence time of drinking water in households, this review summarizes the effectiveness and mechanism of HWTS and combination technologies for DBP control in municipal tap water, and makes a comparison with regard to technologies implementing different removal mechanisms as well as DBPs possessing different natures. Based on these results, this article provides an insight into DBP risk assessment and human health protection.
Data-driven-based determination of influential parameters on local energy loss of slope-tapered culvert
Authors: Cai Xiaowen , Ye Feng , Nassaji Matin Ghazaleh
Published: October 2020

Local energy loss is among the essential parameters of culvert design, in which uncertainty and nonlinearity is controversial. In the present study, seven models were developed with the aid of the experimental data of slope-tapered culverts, and the efficiency of gene expression programing and Gaussian process regression as a kernel-based approach was assessed in predicting the entrance loss coefficient of a slope-tapered culvert. Also, one-at-a-time (OAT) sensitivity analysis was performed to determine the impact of input parameters. The results of both GEP and GPR methods with the performance criteria of R = 0.847, DC = 0.777, RMSE = 0.2 and R = 0.76, DC = 0.718, RMSE = 0.25 showed that the model with input parameters of Froude number (Fr), ratio of headwater to culvert diameter (Hw/D) and ratio of reducer length to barrel length (Lr/L) is the superior model. Although the accuracy of GEP method was slightly higher than GPR, obtained results proved the capability of the applied methods (i.e., high correlation coefficient (R) and coefficient of determination R2 (DC) and low RMSE). Furthermore, OAT sensitivity analysis revealed that Froude number has the most impact on local loss coefficient and could cause a significant increment in model efficiency.
Economic and environmental assessment of water reuse in industrial parks: case study based on a Model Industrial Park
Authors: Boysen Birte , Cristóbal Jorge , Hilbig Jens , Güldemund Almut , Schebek Liselotte , Rudolph Karl-Ulrich
Published: October 2020

Industrial wastewater reuse is a major measure to mitigate the depletion of available freshwater resources in the catchments around industrial areas and to prevent possible future water shortages and the resulting problems for industry, economy and society. Combining a set of environmental aspects and economic aspects of different wastewater treatment technologies, the authors developed a model-based approach for planning and evaluating water reuse concepts in industrial parks. This paper is based on an exemplary Model Industrial Park. The results based on data primarily calculated for Germany show that, for the majority of the indicators, the installation of the Water Reuse Plant seems to be beneficial for all examined reuse options. Considering the economic dimension, due to economies of scale, reuse options with larger volumes of treated water are preferable since the costs per m3 of reuse water are reduced by up to 33%. On the other hand, the environmentally preferable option depends on the respective indicator, e.g. for freshwater eutrophication, the higher the reuse factor, the lower the impact, leading to reductions between 8 and 12%. For climate change, the best option is dependent on the reuse purpose leading to reductions between 8 and 52%.
Application of a decision support tool for industrial and agricultural water reuse solutions in international case studies
Authors: Wencki Kristina , Thöne Verena , Becker Dennis , Krömer Kerstin , Sattig Isabelle , Lischeid Gunnar , Zimmermann Martin
Published: October 2020

Treated wastewater is expected to constitute an essential part of the urban water cycle as an additional water resource in water-scarce or densely populated regions in the future. As decisions on the implementation of water recycling measures should always consider local conditions, the project ‘MULTI-ReUse: Modular treatment and monitoring for wastewater reuse’ has developed a comprehensive sustainability assessment tool, designed to support decision-makers in examining the technical feasibility, economic viability, ecological compatibility and social acceptance of alternative service water supply solutions at local level. This article describes the structure of this sustainability assessment tool and its underlying multi-criteria assessment approach based on 23 evaluation criteria. Already in the development phase, the tool was tested in a German and a Namibian case study. Both case studies are presented with a special focus on the technologies used and the results of the analysis with the sustainability assessment tool. Case study testing proved that the tool is applicable in various environmental and societal settings with widely differing climatic conditions, limited resource availability, for varying feed water qualities and water quality requirements. The comprehensive, straightforward assessment approach enabled the local users to identify the most sustainable supply system or strategy for their decision case.
Impacts of precipitation and topographic conditions on the model simulation in the north of China
Authors: Sun Long , Li Zhijia , Zhang Ke , Jiang Tingting
Published: October 2020

The evaluation of hydrological models for a specific catchment is normally based on the model performance according to the selected performance criteria. However, the catchment rainfall-runoff characteristics could be used for the selection of a suitable hydrological model in study area, which, also, for the problem solve of the model application in ungauged basins. In this study, six conceptual models were applied in three semi-humid or semi-arid catchments to investigate the correlation between catchment characteristics and model structure selection. In addition, the impacts of precipitation and topography in model simulation were analyzed. The results show that runoff generation are highly impacted by catchment topographic index and land cover change, and the influence of slope for river channel is greater than mean slope for the whole catchment due to the runoff generation for partial area. For the catchments under similar climate condition, the impact of topographic features for runoff generation process is greater than the difference of precipitation. It indicates that for a specific catchment, the selection of appropriate model should base on better understanding of the rainfall-runoff relationship. The method of incorporating additional runoff generation module in the traditional model can significantly improve the accuracy of flood simulation.
The energy – pressure nexus in the water supply system
Authors: Ćipranić Ivana , Jevrić Marija , Radulović Milan , Sekulić Goran
Published: October 2020

Due to the importance of overall sustainable development, efficient energy management should be as significant as water resource management within every water supply system. The pressure reduction, as a measure for loss reduction, not only guarantees less leakage but also minimizes energy consumption. The relationship between energy consumption and pressure in water supply systems has been the subject of many previous studies, mainly based on measurements in real systems. However, a methodology for beforehand assessment of energy savings which occur due to the pressure reduction, has not been proposed yet. The paper proposed a method for the assessment of energy savings in relation to pressure reduction, implemented it on the hypothetical water supply system and verified it on the real system. Results led to the conclusion that the proposed methodology can be considered as a successful tool for better energy and water management. It enables water utility management to estimate energy saving in water supply system in advance, based on the hydraulic model of the system.
Multi-objective optimization of energy and greenhouse gas emissions in water pumping and treatment
Authors: Cardenes Iliana , Siddiqi Afreen , Naeini Mohammad Mortazavi , Hall Jim W.
Published: October 2020

A large part of operating costs in urban water supply networks is usually due to energy use, mostly in the form of electricity consumption. There is growing pressure to reduce energy use to help save operational costs and reduce carbon emissions. However, in practice, reducing these costs has proved to be challenging because of the complexity of the systems. Indeed, many water utilities have concluded that they cannot practically achieve further energy savings in the operation of their water supply systems. This study shows how a hybrid linear and multi-objective optimization approach can be used to identify key energy consumption elements in a water supply system, and then evaluate the amount of investment needed to achieve significant operational gains at those points in the supply network. In application to the water supply system for the city of London, the method has shown that up to 18% savings in daily energy consumption are achievable. The optimal results are sensitive to discount rate and the financial value placed on greenhouse gas emissions. Valuation of greenhouse gas emissions is necessary to incentivise high levels of energy efficiency. The methodology can be used to inform planning and investment decisions, with specific focus on reducing energy consumption, for existing urban water supply systems.
Con o sin paraguas
Authors: Tovar María del Carmen
Published: October 2020

La doctora María del Carmen Tovar nos ilustra con una explicación muy práctica sobre los mecanismos naturales que tiene todo inversionista para proteger su inversión; y analiza la relevancia de las llamadas cláusulas paraguas en los Tratados Bilaterales de Inversión. Esto con el objetivo de determinar cuándo un incumplimiento contractual trasciende el ámbito nacional y se convierte también en una violación al derecho internacional.
¿Existe la vida después de la muerte?: Reconocimiento y ejecución de laudos anulados en sede extranjera
Authors: Reinides Yamila , Jiménez Andrea
Published: October 2020

La certeza de obtener un laudo que sea reconocido y ejecutado es el principal motivo por el cual las partes deciden someter su controversia a un arbitraje. Sin embargo, esta seguridad puede verse truncada – entre otros factores – por la interposición del recurso de anulación de laudo antes los tribunales estatales de la sede arbitral, quienes por causales arbitrarias deciden anular el laudo. Dicha situación, genera varias interrogantes, la principal de ellas es qué ocurrirá con el laudo anulado. En ese escenario, el presente artículo busca esclarecer esta incertidumbre a través del análisis de la posibilidad de reconocer y ejecutar un laudo arbitral anulado en otra jurisdicción, establecida en la Convención de Nueva York. De otro lado, se realizará una breve exposición de la doctrina y jurisprudencia de las principales Cortes extranjeras, que han abordado esta problemática. Ello con el propósito de intentar establecer una propuesta de solución que ayude a mitigar dicha incertidumbre.
Ejecute en Perú, ejecute ya...: La apertura de la Ley Peruana de Arbitraje para la ejecución de un laudo extranjero al amparo de la Convención de Nueva York
Authors: Mori Bregante Pablo , Olórtegui Huamán Julio
Published: October 2020

En el presente artículo, los autores realizan un desarrollo de la causal establecida en el inciso a) del numeral 1 del artículo V de la Convención de Nueva York, referida a la no ejecución de un laudo por invalidez del acuerdo (convenio) arbitral, con el propósito de analizar las consecuencias derivadas de solicitar la aplicación de esta causal en el Perú, teniendo en cuenta lo establecido en la Ley Peruana de Arbitraje.
Pengaruh inkuiri terbimbing terhadap kemampuan mengidentifikasi sumber energi di sekitar manusia dan kemandirian belajar IPA
Authors: Prahenti Dindya Sisca , Rusijono Rusijono , Mariono Andi
Published: October 2020

Penelitian ini bertujuan untuk mengetahui pengaruh model inkuiri terbimbing terhadap kemandirian belajar siswa dan kemampuan mengidentifikasi sumber-sumber energi yang ada di lingkungan sekitar manusia pada siswa kelas 2 Sekolah Dasar di Sinergia Worldwide Education Surabaya. Subjek penelitian ini adalah siswa kelas 2 SD di Sinergia Worldwide Education Surabaya yang terbagi ke dalam dua kelas, yaitu kelompok kontrol dan kelompok eksperimen. Waktu pelaksanaan penelitian adalah pada bulan Maret hingga April 2020, yaitu pada semester genap. Metode penelitian yang digunakan adalah Mann Whitney U-test dan Wilcoxon Sign-Test. Model Mann Whitney U-test dan Wilcoxon Sign-Test bertujuan untuk membandingkan hasil dari perolehan nilai pretest dan posttest yang didapatkan antar dua kelompok, serta untuk melakukan uji validasi instrumen penelitian yang digunakan. Hasil dari penelitian ini menunjukkan  terdapat pengaruh model inkuiri terbimbing terhadap kemandirian siswa, karena model inkuiri terbimbing lebih efektif dalam meningkatkan kemandirian belajar siswa, serta terdapat pengaruh model inkuiri terbimbing terhadap kemampuan siswa dalam mengidentifikasi sumber-sumber energi yang ada di sekitar manusia, karena dengan menerapkan model inkuiri terbimbing siswa dapat lebih aktif dalam menjawab pertanyaan-pertanyaan materi.AbstractThis study aims to determine the effect of the guided inquiry model on student learning independence and the ability to identify energy sources in the environment around humans in grade 2 elementary school students at Sinergia Worldwide Education Surabaya. This study's subjects were students of grade 2 Elementary School at Sinergia Worldwide Education Surabaya, which were divided into two classes, namely the control group and the experimental group. The time of research is from March to April 2020. The research method used is the Mann Whitney U-test and Wilcoxon Sign-Test. The Mann Whitney U-test and Wilcoxon Sign-Test models aim to compare the obtained pretest and post-test scores. The Mann Whitney U-test and Wilcoxon Sign-Test models were also used to test the research instruments' validation. The results of this study indicate that the guided inquiry model has an influence on students' independence because the guided inquiry model is more effective in increasing students' learning independence, and there is an influence of the guided inquiry model on students' ability to identify energy sources around humans, because by applying Guided inquiry model students can be more active in answering material questions.
Model aplikasi cybercounseling Islami berbasis website meningkatkan self-regulated learning
Authors: Fahyuni Eni Fariyatul , Romadlon Dzulfikar Akbar , Hadi Nurul , Haris Mochammad Imron , Kholifah Nur
Published: October 2020

Penelitian ini merupakan jenis penelitian dan pengembangan yang bertujuan untuk mengembangkan model aplikasi cybercounseling Islami berbasis website guna membantu memaksimalkan self-regulated learning siswa melalui layanan bimbingan dan konseling berbasis cyber pada era pendemi Covid-19. Jenis penelitian pengembangan ini mengacu pada model Dick, Carey, dan Carey yang terdiri atas 10 tahapan. Hasil penilaian validasi oleh beberapa tim ahli pada model layanan bimbingan konseling melalui cybercounseling berbasis website didapatkan nilai rerata adalah 3,78. Ujicoba individu skor yang dihasilkan sebesar 3,86 dan ujicoba kelompok terbatas skor yang didapat sebesar 3,86. Berdasarkan hasil penilaian tersebut dapat disimpulkan bahwa model layanan bimbingan konseling melalui cybercounseling berbasis website yang dikembangkan dalam kategori sangat layak digunakan sebagai model layanan bimbingan konseling berbasis digital. Dengan demikian model layanan bimbingan konseling melalui cybercounseling berbasis website yang dikembangkan terbukti efektif mampu meningkatkan self-regulated learning yang dapat membantu siswa memfokuskan pencapaian pada tujuan pembelajaran, mengontrol proses pembelajaran, menumbuhkan motivasi sendiri, dan membangun kepercayaan diri guna mendukung serta optimalisasi proses pembelajaran.AbstractThis research is a type of research and development which aims to develop a web-based Islamic cybercounseling application model to help maximize student self-regulated learning through cyber-based guidance and counseling services in the COVID-19 pandemic era. This type of development research refers to the Dick, Carey, and Carey model which consists of over 10 stages. The valid production results by several expert teams of counseling service models through web-based cybercounseling, the mean value of search was 3.78. Individuals with the resulting test score of 3.86 and the limited trial group the score obtained was 3.86. Based on the results of this assessment, the guidance can state that the counseling service model through web-based cyber-counseling developed in the category is very suitable for use as a digital-based counseling model. Thus the counseling service model through web-based cybercounseling that has been developed has proven to be effective in improving self-regulated learning which can help students focus on learning goals, control the learning process, foster self-motivation, and build self-confidence to support and optimize the learning process.
Characterizing Chronic Pain Episodes in Clinical Text at Two Health Care Systems: Comprehensive Annotation and Corpus Analysis
Authors: Carlson Luke A , Jeffery Molly M , Fu Sunyang , He Huan , McCoy Rozalina G , Wang Yanshan , Hooten William Michael , St Sauver Jennifer , Liu Hongfang , Fan Jungwei
Published: October 2020

Background

Chronic pain affects more than 20% of adults in the United States and is associated with substantial physical, mental, and social burden. Clinical text contains rich information about chronic pain, but no systematic appraisal has been performed to assess the electronic health record (EHR) narratives for these patients. A formal content analysis of the unstructured EHR data can inform clinical practice and research in chronic pain.

Objective

We characterized individual episodes of chronic pain by annotating and analyzing EHR notes for a stratified cohort of adults with known chronic pain.

Methods

We used the Rochester Epidemiology Project infrastructure to screen all residents of Olmsted County, Minnesota, for evidence of chronic pain, between January 1, 2005, and September 30, 2015. Diagnosis codes were used to assemble a cohort of 6586 chronic pain patients; people with cancer were excluded. The records of an age- and sex-stratified random sample of 62 patients from the cohort were annotated using an iteratively developed guideline. The annotated concepts included date, location, severity, causes, effects on quality of life, diagnostic procedures, medications, and other treatment modalities.

Results

A total of 94 chronic pain episodes from 62 distinct patients were identified by reviewing 3272 clinical notes. Documentation was written by clinicians across a wide spectrum of specialties. Most patients (40/62, 65%) had 1 pain episode during the study period. Interannotator agreement ranged from 0.78 to 1.00 across the annotated concepts. Some pain-related concepts (eg, body location) had 100% (94/94) coverage among all the episodes, while others had moderate coverage (eg, effects on quality of life) (55/94, 59%). Back pain and leg pain were the most common types of chronic pain in the annotated cohort. Musculoskeletal issues like arthritis were annotated as the most common causes. Opioids were the most commonly captured medication, while physical and occupational therapies were the most common nonpharmacological treatments.

Conclusions

We systematically annotated chronic pain episodes in clinical text. The rich content analysis results revealed complexity of the chronic pain episodes and of their management, as well as the challenges in extracting pertinent information, even for humans. Despite the pilot study nature of the work, the annotation guideline and corpus should be able to serve as informative references for other institutions with shared interest in chronic pain research using EHRs.
Defining Digital Game-Based Learning for Science, Technology, Engineering, and Mathematics: A New Perspective on Design and Developmental Research
Authors: Ishak Shahrul Affendi , Din Rosseni , Hasran Umi Azmah
Published: October 2020

In the modern age, digital games are widely used as informal media for Science, Technology, Engineering, and Mathematics (STEM) education and medical therapy for game-based learning. Digital games provide learners with a graphical system of interaction that enhances scientific concepts within an enjoyable environment. The vastly increasing number of digital games produced in the market affects the quality of STEM digital games while requiring multidisciplinary expertise. This paper proposes a framework for STEM digital game-based learning encompassing input-process-output stages. Several studies from the early 2000s onward were reviewed to discuss and present a new perspective on a framework for the design and development of digital games, particularly for STEM. This proposed framework consists of digital game development as input, experience as a process, and constructs as output. This simple and precise framework will generate a universal product for various types of learners. It can thus be used as a guideline for game designers, developers, and experts to develop STEM digital games and achieve better learning outcomes.
The Use of Virtual Reality Technologies in the Treatment of Duchenne Muscular Dystrophy: Systematic Review
Authors: Baeza-Barragán Maria Rosa , Labajos Manzanares Maria Teresa , Ruiz Vergara Carmen , Casuso-Holgado María Jesús , Martín-Valero Rocío
Published: October 2020

Background

Duchenne muscular dystrophy is a serious and progressive disease affecting one in 3500-6000 live male births. The use of new virtual reality technologies has revolutionized the world of youth rehabilitation.

Objective

We performed a systematic review to study the effectiveness of the use of virtual reality systems applied in the rehabilitation of the upper limbs of individuals with Duchenne muscular dystrophy.

Methods

Between June 2018 and September 2019, we carried out a series of searches in 5 scientific databases: (1) PubMed, (2) Web of Science, (3) Scopus, (4) The Cochrane Library, and (5) MEDLINE via EBSCO. Two evaluators independently conducted the searches following the PRISMA recommendations for systematic reviews for articles. Two independent evaluators collated the results. Article quality was determined using the PEDro scale.

Results

A total of 7 clinical trials were included in the final review. These studies used new technologies as tools for physiotherapeutic rehabilitation of the upper limbs of patients with Duchenne muscular dystrophy. Collectively, the studies showed improvement in functionality, quality of life, and motivation with the use of virtual reality technologies in the rehabilitation of upper limbs of individuals with Duchenne muscular dystrophy.

Conclusions

The treatment of neuromuscular diseases has changed in recent years, from palliative symptom management to preventive methods for capacity building. The use of virtual reality is beginning to be necessary in the treatment of progressive diseases involving movement difficulties, as it provides freedom and facilitates the improvement of results in capacity training. Given that new technologies are increasingly accessible, rehabilitation and physiotherapy programs can use these technologies more frequently, and virtual reality environments can be used to improve task performance, which is essential for people with disabilities. Ultimately, virtual reality can be a great tool for physiotherapy and can be used for Duchenne muscular dystrophy rehabilitation programs to improve patient performance during training.

Trial Registration

PROSPERO International Prospective Register of Systematic Reviews CRD42018102548; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=102548
Economic Value of Data and Analytics for Health Care Providers: Hermeneutic Systematic Literature Review
Authors: von Wedel Philip , Hagist Christian
Published: October 2020

Background

The benefits of data and analytics for health care systems and single providers is an increasingly investigated field in digital health literature. Electronic health records (EHR), for example, can improve quality of care. Emerging analytics tools based on artificial intelligence show the potential to assist physicians in day-to-day workflows. Yet, single health care providers also need information regarding the economic impact when deciding on potential adoption of these tools.

Objective

This paper examines the question of whether data and analytics provide economic advantages or disadvantages for health care providers. The goal is to provide a comprehensive overview including a variety of technologies beyond computer-based patient records. Ultimately, findings are also intended to determine whether economic barriers for adoption by providers could exist.

Methods

A systematic literature search of the PubMed and Google Scholar online databases was conducted, following the hermeneutic methodology that encourages iterative search and interpretation cycles. After applying inclusion and exclusion criteria to 165 initially identified studies, 50 were included for qualitative synthesis and topic-based clustering.

Results

The review identified 5 major technology categories, namely EHRs (n=30), computerized clinical decision support (n=8), advanced analytics (n=5), business analytics (n=5), and telemedicine (n=2). Overall, 62% (31/50) of the reviewed studies indicated a positive economic impact for providers either via direct cost or revenue effects or via indirect efficiency or productivity improvements. When differentiating between categories, however, an ambiguous picture emerged for EHR, whereas analytics technologies like computerized clinical decision support and advanced analytics predominantly showed economic benefits.

Conclusions

The research question of whether data and analytics create economic benefits for health care providers cannot be answered uniformly. The results indicate ambiguous effects for EHRs, here representing data, and mainly positive effects for the significantly less studied analytics field. The mixed results regarding EHRs can create an economic barrier for adoption by providers. This barrier can translate into a bottleneck to positive economic effects of analytics technologies relying on EHR data. Ultimately, more research on economic effects of technologies other than EHRs is needed to generate a more reliable evidence base.
An Ingenious Application-Specific Quality Assessment Methods for Compressed Wireless Capsule Endoscopy Images
Authors: Fante Kinde Anlay , Abdurahman Fetulhak , Gemeda Mulugeta Tegegn
Published: October 2020

Image quality assessment methods are used in different image processing applications. Among them, image compression and image super-resolution can be mentioned in wireless capsule endoscopy (WCE) applications. The existing image compression algorithms for WCE employ the generalpurpose image quality assessment (IQA) methods to evaluate the quality of the compressed image. Due to the specific nature of the images captured by WCE, the general-purpose IQA methods are not optimal and give less correlated results to that of subjective IQA (visual perception). This paper presents improved image quality assessment techniques for wireless capsule endoscopy applications. The proposed objective IQA methods are obtained by modifying the existing full-reference image quality assessment techniques. The modification is done by excluding the noninformative regions, in endoscopic images, in the computation of IQA metrics. The experimental results demonstrate that the proposed IQA method gives an improved peak signal-tonoise ratio (PSNR) and structural similarity index (SSIM). The proposed image quality assessment methods are more reliable for compressed endoscopic capsule images.
The Third Attempt. A New Chance for an Idealist Philosophy
Authors: Sztankó Nándor
Published: October 2020

The message of total non-universality (both sensible content and concept as such are evalued as non-universal) is incompatible with human nature. From this, the exceptional character of my philosophical venture is derived. Essentially, it is a problem of communication. Hence, it is a didactical construction which is central to my paper. The crucial importance of two simple assertions must be emphasized:1)         A finite extension is not divisible infinitely (proposed by Berkeley and Hume)2)         The line does not consist of points (proposed by Hegel)The above two assertions may be called the hard core of idealist philosophy. Both are instrumental in the conception of original environment. Being tied to the original environment is the outstanding fact that explains why the sensible content should be qualified as non-universal.
ANALISIS KESALAHAN BERBAHASA PADA MAJALAH TOGA EDISI III BULAN DESEMBER TAHUN 2018
Authors: Sari Kusuma , Joko Nurcahyo Rizki , Kartini
Published: October 2020

Majalah Toga merupakan majalah karya mahasiswa bidik misi IAIN Surakarta. Majalah ini ditulis menggunakan bahasa Indonesia sehingga dalam penulisan majalah harus sesuai dengan kaidah kebahasaan yang berlaku di era saat ini. Tetapi dalam majalah Toga masih ditemukan beberapa kesalahan dalam penggunaan kaidah maupun kebahasaan yang tidak sesuai dengan kaidah yang berlaku di era saat ini. Tujuan penelitian ini adalah untuk mendiskripsikan bentuk-bentuk kesalahan berbahasa dalam penulisan majalah Toga. Teknik penelitian yang digunakan dalam penelitian ini adalah teknik tulis. Analisis yang dipakai dalam penelitian ini adalah analisis interaktif. Langkahlangkah dalam analisis interaktif meliputi 1) pengumpulan data, 2) pegidentifikasian kesalahan, 3) penjelasan kesalahan, 4) pengklasifikasian kesalahan, pengevaluasian kesalahan. Hasil dari penelitian ini adalah ditemukan berbagai kesalahan berbahasa dalam tataran ejaan dan tataran linguistik seperti fonologi, morfologi, sintaksis, dan semantik. Secara garis besar hasil dari penelitian ini lebih dominan kesalahan dalam tataran ejaan.
Sikap Berbahasa Komunitas Gay Sebagai Informasi untuk Orang Tua Dalam Menjaga Pergaulan Anak
Authors: Ibrahim Nini
Published: October 2020

Penelitian ini bertujuan untuk mengetahui sikap berbahasa yang digunakan oleh komunitas gay (kaum homoseksual) sebagai informasi untuk orang tua dalam menjaga pergaulan anak dan remaja. Metode yang digunakan dalam penelitian ini adalah metode kualitatif deskriptif, yaitu metode yang melukiskan suatu keadaan objektif atau peristiwa tertentu berdasarkan faktafakta yang tampak. Hasil yang ditunjukkan penelitian ini adalah berdasarkan perkembangannya, bahasa komunitas gay yang sebenarnya diadaptasi dari bahasa gaul kreasi Debby Sahertian (1999) yang sudah mengalami beberapa inovasi dalam kosakata. Ada beberapa ketentuan dalam sikap berbahasa yang diutarakan oleh responden tentang struktur bahasa seperti pada kata makarena, makasar, cucok, rempong, ember, dll. yang digunakan oleh komunitas gay dalam berbahasa. Selain itu, berdasarkan hasil wawancara dan penyebaran angket, dapat diketahui bahwa sebagian besar kaum gay tidak berani menunjukkan penggunaan bahasanya di depan masyarakat umum, kecuali saat mereka sedang bersama dengan sesama komunitasnya. Di Indonesia sendiri, gay dianggap sebagai sebuah perkembangan yang negatif. Oleh karena itu, dalam menjaga agar tidak terjerumus dalam komunitas ini, maka orang tua menjadi sosok penting dalam menjaga pergaulan anak dan remaja. Jika perilaku gay dapat diidentifikasi melalui penggunaan bahasanya, orangtua dapat mengecek kegiatan anaknya dalam berkomunikasi, apakah memiliki keanehan atau masih pada taraf bahasa yang normal dan biasa digunakan oleh masyarakat umum.
Pemerolehan Bahasa: Kajian Aspek Fonologi Pada Anak Usia 2-2,3 Tahun
Authors: Rosi Wulandari Gita
Published: October 2020

Penelitian ini menjelaskan pada pemerolehan bahasa anak usia 2 tahun – 2 tahun 3 bulan dari segi fonologi. Di pembahasan fonologi yang terdiri dari pemerolehan vokal dan pemerolehan konsonan. Penelitian ini dilakukan pada bulan Oktober-Desember 2019. Penelitian ini menggunakan metode kualitatif memakai pendekatan studi kasus. Sumber data penelitian ini adalah seorang anak laki-laki yang berinisial MADA saat berusia 2 – 2 tahun 3 bulan. Data yang didapat disimpan melalui rekaman. Selain melalui proses rekaman, data juga dicatat. Dalam artikel ini dapat ditemukan bahwa pemerolehan fonem [a], [i], [u], [e], [ә], dan [o] MADA sudah dikuasai. Fonem yang pertama MADA kuasai ialah [a], dan [u], sedangkan untuk diftong asli belum dapat dilafalkan. Selain itu, konsonan [p], [m], [b], [y], [s], [n], [k], [d], [c], [t], [ɲ], [w], [j], [g], [ŋ], dan [h] sudah mulai dikuasai meskipun masih mengalami kesulitan dalam pengucapan. Fonem yang belum sempurna dikuasai MADA adalah [r].
Variasi dan Fungsi Ragam Bahasa Pada Iklan dan Slogan Situs Belanja Online Shopee
Authors: Dimas Tutik Anisa , Fitriani Nur , Inderasari Elen
Published: October 2020

Penelitian ini berjudul “Variasi dan Fungsi Ragam Bahasa Pada Iklan dan Slogan Situs Belanja Online Shopee” bertujuan untuk mendeskripsikan bentuk variasi dan fungsi ragam bahasa pada iklan dan slogan situs belanja online shopee. Penelitian ini difokuskan pada bentuk variasi iklan dan slogan serta fungsi dan maknanya. Metode yang digunakan adalah metode deskriptif kualitatif dengan mendekripsikan setiap penggunaan iklan dan slogan dalam situs belanja online shopee. Teknik dalam analisis data menggunakan teknik dokumentasi berupa foto, teknik baca, dan teknik catat pada iklan dan slogan shopee. Hasil penelitian menunjukkan bahwa adanya variasi bahasa asing yang berjumlah 6, variasi bahasa gaul berjumlah 2, dan fungsi bahasa berupa fungsi informational, fungsi direktif, serta fungsi ekspresif.
Kajian Psikologis Humanistik Abraham Maslow Pada Tokoh Utama Dalam Novel Surat Dahlan Karya Khrisna Pabichara
Authors: Amalia Nur , Yulianingsih Sinta
Published: October 2020

Penelitian yang berjudul Kajian Psikologi Humanistik Abraham Maslow pada Tokoh Utama dalam Novel Surat Dahlan Karya Khrisna Pabicara bertujuan untuk mendeskripsikan aspek psikologis humanistik serta memberikan interpretasi mengenai psikologi humanistik dengan pendekatan psikologi sastra, yang dapat dijadikan sebagai alternatif pembelajaran sastra. Sumber data penelitian ini adalah novel Surat Dahlan yang diterbitkan oleh PT Mizan Publika. Fokus penelitian berupa kajian psikologi humanistik, pada hierarki kebutuhan yaitu, the physiological needs (kebutuhan fisiologis), the safety needs (kebutuhan rasa aman), the belongingness and love needs (kebutuhan cinta dan rasa memiliki-dimiliki), the esteem needs (kebutuhan harga diri), the needs for self-actualization (kebutuhan aktualisasi diri). Metode penelitian yang digunakan adalah desktriptif-kualitatif Hasil penelitian ini menunjukan bahwa, the physiological needs, tokoh utama (Dahlan) berupa pemenuhan makan dan tidur, tercapainya kebutuhan fisiologis Dahlan, ketika ia menemukan makanan yang telah disiapkan untuknya. The safety needs dibutuhkan Dahlan, dalam bentuk perlindungan dan kebebasan dari kejaran tentara. Terpenuhinya kebutuhan rasa aman Dahlan ketika ia terbebas dari kejaran tentara. The belongingness and love needs, dibutuhkan Dahlan dalam bentuk cinta dan kasih sayang dari lawan jenis, yaitu Nafsiah. Kebutuhan ini terpenuhi, ketika Dahlan berhasil menikahi Nafsiah. The esteem needs, yang pertama kali Dahlan dapatkan adalah pujian, pengakuan dan kepercayaan. Seiring melesatnya karir Dahlan, ia mendapatkan lebih banyak kebutuhan harga diri. The needs for selfactualization adalah kebutuhan terakhir, yang berhasil Dahlan penuhi, dibuktikan dengan Dahlan memiliki sifat jujur, pantang menyerah, menghargai orang lain dan menyukai tantangan.
Representasi Kehidupan Pada Naskah Drama Nyonya-Nyonya Karya Wisran Hadi
Authors: Hairunnisa  , Soviana Devi Wika
Published: October 2020

Beberapa peristiwa memiliki keunikan tersendiri yang biasanya bisa menjadi inspirasi untuk membuat sebuah naskah drama. Dalam penulisan naskah drama, pengarang harus benar-benar memahami dan merasakan setiap adegan demi adegan, dialog demi dialog yang kemudian ditulis kembali menjadi sebuah karya sastra. Melalui pengalaman dan pengetahuan secara potensial memiliki berbagai macam bentuk representasi kehidupan. Objek yang diteliti adalah naskah drama Nyonya-Nyonya karya Wisran Hadi dengan menggunakan pendekatan sosiologi sastra. Penelitian ini menggunakan metode deskriptif. Metode deskriptif adalah pendekatan penelitian yang sumber datanya berupa kata-kata. Metode deskriptif ini bertujuan memaparkan hasil temuan pada proses penelitian berdasarkan tujuan penelitian. Hasil penelitian sosiologi sastra pada naskah drama NyonyaNyonya karya Wisran Hadi terdapat dua poin utama yaitu keteguhan terhadap norma yang berlaku dan kepercayaan pada kekuatan leluhur.
Pembelajaran Bahasa Indonesia Bagi Penutur Asing Menggunakan Metode Darmawisata
Authors: Jannah Raudhatul , Gusti Yanti Prima
Published: October 2020

Penelitian BIPA ini memaparkan proses serta cara belajar Bahasa Indonesia untuk Penutur Asing dari aspek belajar BIPA menggunakan metode darmawisata. Penelitian dilakukan di Museum-museum Kota Tua dan Taman Mini Indonesia Indah, dilaksanakan bulan November-Desember 2019. Penelitian ini memakai pendekatan kualitatif dengan desain deskriptif, memaparkan penyelenggaraan pembelajaran BIPA secara faktual, laporan ditulis dengan naratif dan mempunyai sifat kreatif. Sumber data yang diperoleh dari 2 mahasiswa Thailand dan 2 mahasiswa Somalia yang belajar di Universitas Muhammadiyah Jakarta (UMJ). Data artikel dihimpun melewati observasi, darmawisata, hasil catatan dan tanya jawab seseorang. Hasil memikirkan dan melakukan metode darmawisata menyatakan salah satu metode efisien digunakan untuk belajar bahasa Indonesia untuk pemelajar asing, sekaligus mengetahui adat istiadat kebudayaan sejarah yang ada di Indonesia. Penggunaan metode darmawisata dapat meningkatkan kualitas proses pembelajaran bahasa Indonesia mahasiswa Thailand dan Somalia di UMJ tahun ajaran 2019/2020. Ini ditunjukkan dari keaktifan dan keuletan mahasiswa dalam proses atau cara perbuatan menjadikan belajar bahasa Indonesia lebih diutamakan.
Kohesi Wacana Dalam Kumpulan Puisi Berguru Kepada Rindu Karya Acep Zamzam Noor
Authors: Joko Nurcahyo Rizki , Nandasari Viana , Dewi Zulaikha Rifa
Published: October 2020

Puisi diartikan sebagai salah satu bentuk karya sastra yang dikategorikan ke dalam sebuah struktur wacana yang utuh, sehinga dalam pemakaian bahasanya harus mengikuti dan selaras dengan berkembangnya suatu zaman. Penelitian ini bertujuan untuk menganalisis dan mendeskripsikan penggunaan kohesi gramatikal dan penggunaan kohesi leksikal yang terdapat dalam Kumpulan Puisi “Berguru Kepada Rindu” Karya Acep Zamzam Noor. Teori yang digunakan dalam penelitian ini adalah teori jenis kohesi wacana milik Sumarlam.Metode penelitian yang digunakan dalam penelitian ini adalah metode penelitian kualitatif. Data dalam penelitian ini berasal dari bait-bait dalam kumpulan puisi “Berguru Kepada Rindu” karya Acep Zamzam Noor. Teknik pengumpulan data dalam penelitian ini adalah teknik purpose sampling. Analaisis data dilakukan dengan cara mengklasifikasikan pirantipiranti kohesi dalam sebuah wacana menggunakan teori yang dikemukakan Sumarlam. Berdasarkan temuan data-data yang dianalisis, piranti kohesi yang paling dominan yang terdapat pada Buku Kumpulan Puisi “Berguru Kepada Rindu” Karya Acep Zamzam Noor adalah piranti kohesi leksikal.