bluuebunny/crossref_metadata_2025 huggingface dataset:
Validity of Ultrasound Compared with Magnetic Resonance Imaging in Evaluation of Osteochondritis Dissecans of the Distal Femur in Children
Authors: Jungesblut Oliver D. , Berger-Groch Josephine , Meenen Norbert M. , Stuecker Ralf , Rupprecht Martin
Published: February 2019

Objective

Magnetic resonance imaging (MRI) is currently the gold standard to diagnose and monitor osteochondritis dissecans (OCD) of the knee. The purpose of this study was to evaluate for the first time if ultrasound imaging can be used to visualize osteochondritis dissecans of the distal femur.

Design

From May 2008 to December 2013, 44 children (26 boys and 18 girls) presenting with OCD of the knee in our department were examined and evaluated by ultrasound imaging. Mean age at diagnosis was 11.8 ± 2.2 years. Two independent experienced orthopedic surgeons analyzed the localization, stage, and the size of the OCD via ultrasound and compared the results with the MRI findings.

Results

Ultrasonic examination has limitations in assessing the OCD stage I and therefore is not suitable for evaluating this stage of the disease. In stages II to IV, a good correlation to MRI regarding defect localization and size can be found, when the defect is localized in a region that is accessible to ultrasonic examination.

Conclusion

Ultrasonic scan is an appropriate tool for the screening and monitoring of OCDs stages II to IV. It provides an inexpensive and readily available alternative to MRI. In addition, the healing process of higher grade defects as well as the screening of the opposite side can also be performed by ultrasound. Detection of defects being localized close to the intercondylar notch or far posterior on the lateral condyle are limitations for the use of ultrasound.
Acute diagonal-induced ST-elevation myocardial infarction and electrocardiogram-guidance in the era of primary coronary intervention: New insights into an old tool
Authors: Abu Fanne Rami , Kleiner Shochat Michael , Shotan Avraham , Frimerman Aharon , Maraga Emad , Amsalem Naama , Levi Yaniv , Meisel Simcha R
Published: February 2019

Background:

Previous studies, published before the advent of primary reperfusion, described the electrocardiographic features of ST-segment elevation myocardial infarction (STEMI) caused by total diagonal artery occlusion, as demonstrated at pre-discharge coronary angiography. We aimed to assess the electrocardiographic and echocardiographic features in STEMI unequivocally attributed to a diagonal lesion in the era of primary coronary intervention.

Methods:

The electrocardiograms and echocardiograms of patients sustaining STEMI caused by diagonal artery involvement were compared with those of patients with STEMI attributed to proximal or mid left anterior descending artery (LAD) lesions. ST-segment deviations were measured at four different points in each lead and analyzed against TIMI flow and SNuH score. The electrocardiographic and echocardiographic features of each group were mapped.

Results:

In contrast to previous studies claiming an ever-present incidence of at least 1-mm ST-segment elevation in leads I and aVL with diagonal STEMI, we report 86% of any ST-elevation in leads I, aVL and V2 (64–71% for ST-elevation >1 mm). Both higher SNuH score and pre-intervention TIMI flow were associated with larger lateral ST-elevations (85.7% and 86.4–95.5%, respectively). Higher prevalence of ST-depression in the inferior leads reflecting reciprocal changes was observed in patients with diagonal-induced STEMI (57–76% vs. 24–51% in LAD obstructions, p <0.05).

Conclusion:

The most sensitive and predictive sign for acute ischemia was any degree of ST-deviation measured 1 mm beyond the J point. ST-elevations in I, aVL and V2, sparing V3-V5, strongly favor isolated diagonal lesion. Proximal LAD lesion lacking ST-segment elevations in leads I and aVL is primarily due to wraparound LAD anatomy.
Do not follow the bone, follow the nerve ultrasound-guided stellate ganglion block: a reconfirmation
Authors: Elmofty Dalia H , Eckmann Maxim
Published: February 2019

Indirect and direct methods have been used to localize the stellate ganglion. Identifying the C6 and C7 transverse process can be a technical challenge for practitioners when performing an ultrasound-guided stellate ganglion block. Following the nerve roots from the interscalene plexus into the corresponding foramen can serve as a reconfirmation for identifying the C6 and C7 transverse process.
Type B3 thymoma with marked neuroendocrine differentiation: Report of a case
Authors: Sato Kiyoshi , Fumimoto Satoshi , Kataoka Takayuki , Ichihashi Yoshio , Ochi Kaoru , Satomi Hidetoshi , Hanaoka Nobuharu , Okada Yoshikatsu , Katsumata Takahiro
Published: February 2019

Thymomas are tumors originating from the thymus epithelial cells and are the most common tumors of the anterior mediastinum. They have been classified into types A, AB, B1, B2, and B3 by the World Health Organization. Type B3 thymoma is composed of epithelial cell sheets with mild to moderate atypia and scant lymphocytes. An association between thymic carcinoma and neuroendocrine differentiation has been observed by some authors. However, cases of type B3 thymoma with neuroendocrine differentiation are very rarely discussed in the literature. A 68-year-old woman was referred to our hospital with an abnormal shadow on a chest roentgenogram. Chest computed tomography showed that the lesion was located in the anterior mediastinum. She underwent surgery, and the tumor was diagnosed as a type B3 thymoma with neuroendocrine differentiation. An extremely rare case of a type B3 thymoma showing neuroendocrine differentiation is presented herein.
Lp-PLA2, a new biomarker of vascular disorders in metabolic diseases
Authors: De Stefano Alessandro , Mannucci Liliana , Tamburi Federica , Cardillo Carmine , Schinzari Francesca , Rovella Valentina , Nisticò Steven , Bennardo Luigi , Di Daniele Nicola , Tesauro Manfredi
Published: February 2019

Metabolic diseases are chronic disorders correlated to a greater risk of cardiovascular event and death. Recently, many data have sustained the biological link between microvascular dysfunction, oxidative stress, vascular inflammation, and metabolic diseases. The determination of new and specific blood biomarkers of vascular inflammation associated with obesity-related metabolic syndrome (MetS) and diabetes such as lipoprotein-associated phospholipase A2 (Lp-PLA2) could be useful to identify subject with high risk of cardiovascular events. Lp-PLA2 participates by a crucial role in microvascular dysfunction and oxidative stress showing positive association with metabolic disorders. In this review, we will argue the evolving role of Lp-PLA2 in predicting cardiovascular events in metabolic disease patients.
Detection of Mycobacterium tuberculosis in AFB smear-negative sputum specimens through MTB culture and GeneXpert® MTB/RIF assay
Authors: Rasool Ghulam , Khan Arif Muhammad , Mohy-Ud-Din Raza , Riaz Muhammad
Published: February 2019

Tuberculosis (TB) is an important public health issue around the globe which is a chronic infectious disease and is still one of the major challenges for developing countries. The emergence of drug-resistant TB makes the condition worse and there is an urgent need of fast, highly sensitive diagnostic methods. This study was undertaken to evaluate the performance of GeneXpert® MTB/RIF assay and MTB culture for the detection of Mycobacterium tuberculosis (MTB) in sputum smear-negative pulmonary TB/drug-resistant tuberculosis (DR-TB) suspects. A total of 168 sputum smear-negative TB suspects were recruited for the study. Among the suspected TB cases, 52.98% were male and 47.02% were females with the mean age of 42 ± 17.6 years. All the sputum specimens collected from the study population were subjected to Ziehl–Neelsen (ZN) smear microscopy, GeneXpert MTB/RIF assay, and MTB culture. The results revealed that, out of 168 acid-fast bacilli (AFB)/ZN smear microscopy–negative sputum specimens, 48 (28.57%) and 58 (34.52%) were detected MTB positive by GeneXpert MTB/RIF assay and MTB culture, respectively, while 120 (71.43%) and 110 (65.48%) suspected TB cases were confirmed negative by GeneXpert MTB/RIF assay and MTB culture, respectively. The study concluded that GeneXpert assay was found to be a rapid and accurate tool for MTB detection in smear-negative sputum specimens. GeneXpert has advantage over ZN smear microscopy and MTB culture as it detects MTB and rifampicin resistance simultaneously within 2 h with minimal biohazards.
Defining Exposures in Professional Football: Professional American-Style Football Players as an Occupational Cohort
Authors: Grashow Rachel G. , Roberts Andrea L. , Zafonte Ross , Pascual-Leone Alvaro , Taylor Herman , Baggish Aaron , Nadler Lee , Courtney Theodore K. , Connor Ann , Weisskopf Marc G.
Published: February 2019

Studies of professional American football players have shown that football-related activities lead to acute injuries and may have long-term adverse health outcomes including osteoarthritis, neurocognitive impairment, and cardiovascular disease. However, the full complement of what constitutes professional football exposure has yet to be effectively articulated. Most likely, professional football exposure encompasses a multifaceted array of experiences including head impacts and joint stresses, long-term pain medication use, dietary restrictions, and strenuous training regimens. To study the health of professional American football players, characterizing the group as an occupational cohort and taking advantage of methods established within the discipline of occupational epidemiology may be beneficial. We conducted a narrative review of existing football research, occupational epidemiological methods papers, and occupational medicine studies. Here we describe the traditional occupational epidemiological approach to assessing exposure in a novel cohort and show how this framework could be implemented in studies of professional football players. In addition, we identify the specific challenges associated with studying an elite athletic occupational group, including the healthy worker effect and other types of selection and information biases, and explore these in the context of existing studies of football-related health. The application of well-established occupational epidemiological methods to professional football players may yield new insights into the effects of playing exposure and may provide opportunities for interventions to reduce harm.
A Rare Case of Bartonella Encephalitis With Hemiplegia
Authors: Rosas Laura , Rao Kavya , McGough Christine , Becker Ashley
Published: February 2019

The authors describe a 12-year-old girl with an atypical presentation of Bartonella encephalitis. She presented with fever and altered mental status and developed flaccid paralysis of her left upper extremity a day later. An electroencephalogram showed slowing over her right hemisphere. She had mild leukocytosis and bandemia, but her imaging and cerebrospinal studies were unrevealing. After five days, her symptoms resolved and she was discharged home on doxycycline due to suspicion for Bartonella encephalitis. The patient admitted to playing with a kitten two months prior, but she lacked the classic regional lymphadenopathy. Bartonella titers were sent during her hospitalization and returned positive after her discharge. Cat scratch disease neurologic manifestations are uncommon, with hemiplegia being exceedingly rare. This case illustrates that focal neurologic signs may develop during cat scratch disease infection and suggests that cat scratch disease encephalitis should be considered during evaluation of a pediatric patient with acute flaccid paralysis.
Does History of Prematurity Prompt Blood Pressure Evaluations at Primary Care Visits?
Authors: Kornfeld Benjamin D. , Finer Gal , Banks Laura E. , Bolanos Liliana , Ariza Adolfo J.
Published: February 2019

Prematurity is a risk factor for elevated blood pressure (BP). We performed a mixed-methods study of care patterns and awareness of early BP screening recommendations for infants born prematurely (IBP) by interviewing/surveying providers on practice- and provider-level BP screening. IBP’s records were reviewed for BP screening documentation, demographics, and gestational age (GA). Visits <33 months were reviewed for anthropometrics, BP, and comorbidities. Chi-square analysis evaluated BP screening by GA and comorbidities. Twenty-six of 49 practices completed interviews; 81% had infant BP equipment available; 4% had BP measurement protocol for IBP. Twenty-eight of 86 providers were aware of screening guidelines; none reported routine assessment. Twenty-eight of 118 IBP had ≥1 BP documented; 43% had BP ≥90th percentile. Screening did not differ by GA group. Kidney-related diagnosis was associated with more frequent BP screening ( P = .0454). BP is not routinely measured though often elevated before age 3 in IBP.
Comparative Eye Effect of Unilateral Intravitreal Bevacizumab, Ranibizumab, and Aflibercept for Diabetic Macular Edema
Authors: Malbin Brett , Patel Harshad P. , He Yuguang , Le Kim , Lin Xihui
Published: February 2019

Purpose:

The purpose of this article is to compare the fellow-eye effect of unilateral intravitreal antivascular endothelial growth factor (anti-VEGF) treatment (bevacizumab, ranibizumab, and aflibercept) in patients with bilateral diabetic macular edema (DME).

Methods:

A retrospective review was conducted of hemoglobin A1c-matched groups receiving unilateral anti-VEGF injections (1.25 mg bevacizumab, 0.5 mg ranibizumab, and 2 mg aflibercept) in which the second eye had subclinical DME. Two main outcome measures evaluated were central subfield thickness (CST) on optical coherence tomography and best-corrected visual acuity (BCVA). Patients were excluded if they had poor BCVA (< 20/100) or had received laser, vitrectomy, filtering surgery, or pharmacologic treatments in the 3 months prior in the noninjected eye.

Results:

A total of 2073 total intravitreal anti-VEGF injections for DME were reviewed and 94 met the inclusion criteria: 40 bevacizumab, 33 ranibizumab, and 21 aflibercept. At 1 month, the CST of the fellow eye in the bevacizumab group had a statistically significant decrease (296.82 µm to 292.46 µm, P = .01) while both the ranibizumab and aflibercept groups trended toward worsening edema. When compared to ranibizumab and aflibercept, the CST in the noninjected eye in the bevacizumab group had improvements of –15.03 µm and –13.47 µm, respectively ( P < .019). When bevacizumab was switched to ranibizumab or aflibercept, the edema in the fellow eye worsened by +49.60 µm and +5.50 µm, respectively.

Conclusion:

Bevacizumab injection has a statistically significant therapeutic effect in the fellow eye when compared to those treated with ranibizumab and aflibercept. The edema in the fellow eye worsened when injection in the primary eye was switched away from bevacizumab.
Treatment Outcomes of Pediatric Patients With Ewing Sarcoma in a War-Torn Nation: A Single-Institute Experience From Iraq
Authors: Majeed Sazgar S. , Muhammad Hawzheen A. , Ali Jalil S. , Khudhair Hassanain H. , Said Ayah , Arif Shkar O. , Murad Karzan M. , Gendari Ali H. , Muhsin Bamo M. , Mohammed Shwan A. , Mula-Hussain Layth
Published: February 2019

PURPOSE

Ewing sarcoma (ES) is a relatively rare, highly malignant tumor of the musculoskeletal system. It is the second most common malignant bone tumor in children and adolescents in the age group of 5 to 20 years. The aim of this study was to identify the treatment outcomes of pediatric patients with ES in Sulaimani governorate, Iraq.

PATIENTS AND METHODS

This was a retrospective study that reviewed the medical records of pediatric patients with ES who were managed between 2009 and 2015, with follow-up until late 2017. Patient- and tumor-related factors were correlated with clinical outcomes.

RESULTS

A total of 31 pediatric patients with ES were included in this study. All the patients received chemotherapy and radiotherapy, whereas only 14 patients underwent surgical resection and just eight had free surgical margins. The median age at diagnosis was 13 years, 58% were male, and 42% were female. The presenting symptoms at diagnosis were mostly pain (67.7%) and palpable mass (25.8%). The primary tumor was located in the extremities (51.6%), the thoracic cage (19.4%), the pelvis (16.1%), and the lumbar vertebrae (12.9%). Approximately two thirds of the patients (61.3%) had localized disease at the time of presentation. The 5-year overall survival was 19%, and the 5-year recurrence-free survival was 34%.

CONCLUSION

Clinical outcomes of ES in pediatric patients in our war-torn nation, Iraq, are still markedly inferior to the published outcomes from stable, developed nations. Additional large and multicenter national studies are required. Diagnostic and therapeutic measures need improvement, and multidisciplinary and comprehensive cancer-integrated approaches are vital for better outcomes.
Posterior Cortical Atrophy
Authors: Schott Jonathan M. , Crutch Sebastian J.
Published: February 2019

PURPOSE OF REVIEW

This article presents an overview of the clinical syndrome of posterior cortical atrophy (PCA), including its pathologic underpinnings, clinical presentation, investigation findings, diagnostic criteria, and management.

RECENT FINDINGS

PCA is usually an atypical form of Alzheimer disease with relatively young age at onset. New diagnostic criteria allow patients to be diagnosed on a syndromic basis as having a primary visual (pure) form or more complex (plus) form of PCA and, when possible, on a disease-specific basis using biomarkers or underlying pathology. Imaging techniques have demonstrated that some pathologic processes are concordant (atrophy, hypometabolism, tau deposition) with clinical symptoms and some are discordant (widespread amyloid deposition). International efforts are under way to establish the genetic underpinnings of this typically sporadic form of Alzheimer disease. In the absence of specific disease-modifying therapies, a number of practical suggestions can be offered to patients and their families to facilitate reading and activities of daily living, promote independence, and improve quality of life

While rare, PCA is an important diagnostic entity for neurologists, ophthalmologists, and optometrists to recognize to allow for early accurate diagnosis and appropriate patient management. PCA provides an important opportunity to investigate the causes of selective vulnerability in Alzheimer disease.
Serotonin inhibits axonal regeneration of identifiable descending neurons after a complete spinal cord injury in lampreys
Authors: Sobrido-Cameán Daniel , Robledo Diego , Sánchez Laura , Rodicio María Celina , Barreiro-Iglesias Antón
Published: February 2019

Classical neurotransmitters are mainly known for their roles as neuromodulators, but they also play important roles in the control of developmental and regenerative processes. Here, we used the lamprey model of spinal cord injury to study the effect of serotonin in axon regeneration at the level of individually identifiable descending neurons. Pharmacological and genetic manipulations after a complete spinal cord injury showed that endogenous serotonin inhibits axonal regeneration in identifiable descending neurons through the activation of serotonin 1A receptors and a subsequent decrease in cAMP levels. RNA sequencing revealed that changes in the expression of genes that control axonal guidance could be a key factor on the serotonin effects during regeneration. This study provides new targets of interest for research in non-regenerating mammalian models of traumatic CNS injuries and extends the known roles of serotonin signalling during neuronal regeneration.
Ni–Co–Mn Oxyhydroxide Nanosheets with a Semiconductor-Like Electronic Structure
Authors: Suzuki Shinya , Shimamoto Kento , Miyayama Masaru
Published: February 2019

In this study, the yield of nanosheets fabricated through the exfoliation of Li(Ni0.33Co0.33Mn0.34)O2 in aqueous solution was enhanced by performing an additional chemical oxidation step. The lateral dimensions and thickness of the obtained nanosheets were estimated via atomic force microscopy, and their chemical composition was determined using thermogravimetry, chemical composition analysis, and X-ray absorption near edge structure measurements, while their local crystal structure was examined using Raman spectroscopy and X-ray absorption fine structure techniques. In addition, the electrode properties of the restacked nanosheets in aqueous KOH solution were compared with those of the layer-structured bulk material.
Η προώθηση του Διαπολιτισμικού Διαλόγου στην εικοσαετή ατζέντα της UNESCO για την Ανώτατη Εκπαίδευση (1998-2017) :Από τη θεωρία στην πράξη;
Authors: Πίτσου Χαρίκλεια , Αστεριώτη Νίκη
Published: February 2019

Τις τελευταίες δεκαετίες του 21ου αιώνα στην κοινωνία της παγκοσμιοποίησης και της πολιτισμικής πολυμορφίας διεθνείς και περιφερειακοί οργανισμοί έχουν θέσει στην ατζέντα τους την προώθηση του διαπολιτισμικού διαλόγου. Ειδικά, ο διαπολιτισμικός διάλογος κατέχει υψηλή θέση στην ατζέντα της UNESCO, ένας διεθνής οργανισμός που ασχολείται διαρκώς και επισταμένα με θέματα εκπαίδευσης. Στην παρούσα ερευνητική εργασία εξετάζεται με ποιες συνθήκες προωθείται ο «διαπολιτισμικός διάλογος» στο περιεχόμενο των τελικών εκθέσεων των παγκόσμιων διασκέψεων (1998; 2009) και της σύσκεψης (2003) του οργανισμού για την ανώτατη εκπαίδευση. Το θέμα προς συζήτηση που προκύπτει είναι με ποιες συγκεκριμένες πρακτικές η ανώτατη εκπαίδευση θα προωθήσει την ανάπτυξη του διαπολιτισμικού διαλόγου στις δομές της. Τα ερευνητικά αποτελέσματα που προέκυψαν μέσω της ανάλυσης περιεχομένου έδειξαν ότι ο διαπολιτισμικός διάλογος μπορεί να προωθηθεί στην ανώτατη εκπαίδευση μέσω της διεθνοποίησής της, με διαπανεπιστημιακά δίκτυα και τη δημιουργία μιας δημοκρατικής κουλτούρας
The Formation of a Situation of Success As a Method of Improving the Quality of Training of Students of Secondary Vocational Education in Accordance with International Standards
Authors: Пахневская О. , Pahnevskaya O. , Романченко М. , Romanchenko M.
Published: February 2019

The article outlines the main priorities for the development of secondary vocational education in the regions of the Siberian Federal district. The author investigates the criteria infl uencing the improvement of the quality of training of students of secondary vocational education (SVE), in accordance with international standards, attempts to obtain an objective assessment of the quality of training carried out by professional educational organizations through detailed monitoring.
Methods of calculation of building structures: theory and problems with implementation in the software complex Scilab
Authors: Тухфатуллин Борис , Tuhfatullin Boris , Черняк Маня , Chernyak Manya
Published: February 2019

The main provisions of the finite element method for the calculation of flat rod systems, the elements of which work on tension-compression and bending, are considered in the textbook. The texts of programs that implement the algorithms described in the manual in the open development environment of applications for engineering and scientific calculations of Scilab are given.
The manual is intended for bachelors of professional training: "Industrial and civil construction", "engineering and estimate activities in construction", for students of the specialty "Construction of unique buildings and structures" specialization "Construction of high-rise and long-span buildings and structures", as well as undergraduates of the program " Structural calculations in SCAD Office and information modeling of structures of buildings and structures (BIM)".
Editorial
Authors: Soares Adriana Benevides , Tsallis Alexandra Cleopatre , Jacó Vilela Ana Maria , Mendes Deise Maria Fernandes , Quadros Laura Cristina De Toledo , Valentim Renata Patrícia Forain de , Darriba Vinicius Anciães
Published: February 2019

Adriana Benevides Soares, Alexandra Cleopatre Tsallis, Ana Maria Jacó Vilela, Deise Maria Fernandes Mendes, Laura Cristina de Toledo Quadros, Renata Patrícia Forain de Valentim, Vinicius Anciães Darriba
Experiências na família de origem que repercutem no clima familiar dos descendentes
Authors: Costa Ramona Daniela Bernardo , Costa Crístofer Batista da , Mosmann Clarisse Pereira , Falcke Denise
Published: February 2019

As características do sistema familiar podem ser fatores de risco ou proteção para o desenvolvimento dos seus membros. Na família, o indivíduo constitui sua identidade e seu repertório inicial de habilidades emocionais, cognitivas e sociais que usará na vida adulta. O objetivo deste estudo foi investigar se as experiências na família de origem reverberam no clima familiar dos seus descendentes, e o poder preditivo das variáveis encontradas. Foram avaliadas 372 pessoas, sendo 186 mulheres e 186 homens. A idade dos participantes variou de 19 a 81 anos (M = 39,92; DP = 12,62) e o tempo de relacionamento de 1 a 56 anos (M = 14,81; DP = 11,69). Foram utilizados os questionários Family Background Questionnaire (FBQ) e Inventário do Clima Familiar (ICF). Os dados foram analisados por meio de correlação de Pearson e regressão linear método stepwise. Os resultados indicaram que todas as experiências da família de origem se correlacionaram com pelo menos uma das dimensões do clima familiar. O estilo de decisão materno e abuso de substâncias paterno vivenciados na infância e adolescência na família de origem foram as variáveis preditoras do clima familiar atual dos participantes.
Família e instituições de acolhimento nos cuidados a adolescentes vítimas de incesto
Authors: Carvalho Aline Luiza de , Stengel Márcia
Published: February 2019

Mesmo com as mudanças atuais em sua estrutura, papéis e funções, a família ainda mantém sua importante contribuição na formação subjetiva dos seus membros, embora vá perdendo sua centralidade. Quando nela apresenta relações conflituosas, admitindo a distorção de conceitos e valores entre o grupo, apresentam-se ainda mais dificuldades de convívio. Diante disto, como avaliar a experiência do incesto na representação deste grupo? Como ponderar a percepção e mudanças das rotinas quando as jovens, que sofreram com a violência sexual intrafamiliar, saem de suas residências para viver em uma instituição? E repercussões da triangulação (adolescente, família e instituição)? Buscou-se, portanto, aproximar esta realidade, comum às vítimas de violência, objetivando compreender o vínculo que se estabelece entre estas três representações. Observou-se que a situação de acolhimento institucional as tiram da história já constituída e as coloca em um outro lugar, para elas inseguro e incerto, onde são obrigadas a deixar suspensas a vida e relações anteriores, para conviver com pessoas não conhecidas até a solução do caso. Verificou-se dificuldades de manutenção das antigas e estabelecimento de novas relações, considerando fragilização dos laços desde a separação familiar, das dificuldades de identificação institucional e de estabelecimento de referências contínuas.
Estresse e Estratégias de Enfrentamento de Gestores de Saúde
Authors: Sousa Kelyane Oliveira de , Barros Lívia De Melo
Published: February 2019

A pesquisa teve como objetivo identificar as estratégias de enfrentamento do estresse, utilizadas pelos gestores dos programas de atenção à saúde do município de Aracaju. Foi adotada a abordagem qualitativa, com delineamento transversal e, para coleta de dados, foi utilizado questionário sócio demográfico e entrevistas narrativas. A análise e interpretação dos dados foram realizadas a luz da Análise Textual Discursiva. Sobre as consequências do estresse vivenciado, os impactos foram identificados no contexto do trabalho e na vida pessoal. Já com relação às estratégias de enfrentamento, foi constatada a utilização maior de recursos disponíveis no âmbito pessoal do que aqueles voltados à origem do problema. Como principal proposta, foi colocada a criação de um programa de competências sociais, voltado para os gestores em saúde.
Ensino de avaliação psicológica: dificuldades relatadas por uma amostra de docentes brasileiros
Authors: Ambiel Rodolfo Augusto Matteo , Baptista Makilim Nunes , Bardagi Marucia Patta , Santos Acácia Aparecida Angeli dos
Published: February 2019

Existem questões relativas ao ensino dos métodos e técnicas de Avaliação Psicológica (AP) que não têm sido suficientemente exploradas. Neste sentido, o presente estudo buscou identificar as dificuldades percebidas pelos docentes no ensino de avaliação psicológica nos cursos de graduação. Participaram do estudo 93 docentes (67,7% mulheres) de 13 estados brasileiros, com idades entre 24 e 63 anos, em uma amostra de conveniência. Os participantes responderam a uma questão aberta e as respostas foram submetidas à analise de conteúdo. Entre os resultados destaca-se que as categorias principais de resposta estiveram relacionadas à infraestrutura institucional; currículo dos cursos; atitude dos alunos e de docentes frente à disciplina; atuação docente em AP; psicólogos enquanto modelos de atuação. Os achados revelam a necessidade de um amplo debate sobre o ensino de avaliação psicológica de forma a favorecer a formação na área tanto em nível de graduação como na pós-graduação e apontam para a importância da criação de especialidade profissional na área.
Estados incomuns de consciência em parturientes: a partolândia enquanto potencial para o desenvolvimento da mulher
Authors: Lima e Silva Leonardo Xavier de , Ferreira Aurino Lima , Lima Luiziane Souza Vasconcelos de
Published: February 2019

A assistência ao parto passou por importantes transformações nos últimos séculos. Neste processo, o modelo tecnocrático tornou-se hegemônico, promovendo uma atitude passiva nas mulheres. Evidências mostram, entretanto, que em trabalho de parto a mulher é tomada por estados incomuns de consciência, conhecidos como partolândia, que a tornam ativamente apta ao efetivo trabalho de parto, e a uma experiência de vida positivamente marcante. Objetivou-se discutir como a emergência desses estados potencializa melhores desfechos de parto e promove o crescimento pessoal da mulher. Assim, realizou-se reflexão teórica baseada no modelo integral de Wilber, na teoria do território de nascimento de Fahy, levando em conta os modos contemporâneos de assistência ao parto (Davies-Floyd), e uma visão arquetípica de transformação feminina (Nogueira). A partolândia apresenta-se enquanto modificação na percepção de espaço e tempo, emocionalidade e intuição aguçadas, insights psíquicos, revivescência de traumas etc. Conhecer os estados de consciência da mulher no parto, e os meandros do território de nascimento no qual emergem, pode auxiliar na assistência à parturição, além de viabilizar transformações que impliquem em desenvolvimento psicológico para a mulher.
Emotional Intelligence: A Vital Need
Authors: Mendes Marcelo Simões
Published: February 2019

Goleman, Daniel. (2012). Inteligência Emocional: a teoria revolucionária que define o que é ser inteligente. (M. Santarrita, Trans.). Rio de Janeiro: Objetiva. 383p.
RELAÇÃO ENTRE A CONSENSUALIDADE ADMINISTRATIVA E O MODELO COOPERATIVO DO PROCESSO CIVIL BRASILEIRO: O CONTEXTO DE CRIAÇÃO DAS CÂMARAS DE MEDIAÇÃO E CONCILIAÇÃO NA ADMINISTRAÇÃO PÚBLICA
Authors: Niebuhr Pedro de Menezes , Oliveira Cláudio Ladeira de , Quint Gustavo Ramos da Silva
Published: February 2019

O artigo aborda a nova postura da Administração Pública a partir do fenômeno da consensualidade, observada pela releitura de alguns dos institutos clássicos do Direito Administrativo. Sugere-se uma relação desse novo agir com o modelo cooperativo sedimentado pelo Código de Processo Civil, com ênfase nos mecanismos consensuais de solução de conflitos, em especial, a mediação e a conciliação. Examinam-se as previsões atinentes às câmaras de conciliação e mediação na Administração Pública, bem como o regramento próprio da mediação e da autocomposição de litígios nesta seara, apontando-se algumas possibilidades e limitações. Conclui-se que o Código de Processo Civil vai ao encontro do novo paradigma administrativo, ao tornar obrigatória a existência de câmaras de conciliação e mediação para facilitar a autocomposição de litígios. O método de pesquisa utilizado é dedutivo, com base em pesquisa bibliográfica
Synthesis and Antibacterial Evaluation of Hydrazone Derivatives Bearing 6-Chlorothieno[3,2-c]pyridine Moiety
Authors: Rao N. Sree Lakshmana , Basaveswara Rao Mandava V. , Prasad K.R.S.
Published: February 2019

The present investigation describes the overall preparation of 6-chlorothieno[3,2-c]pyridine-2-carbohydrazide-hydrazone subsidiaries (7a-r) from industrially accessible ethyl-4,6-dichloronicotinate as starting material. The synthesis of these derivatives involve some prominent reactions such as (i) NaBH4 reduction of ethyl ester group (ii) MnO2 oxidation of 1º alcohol (iii) cyclization of aldehyde with ethylmercapto acetate leading to thieno[3,2-c]pyridine ring (iv) hydrazinolysis of the ethyl group (v) condensation of selected aldehydes with 6-chlorothieno[3,2-c]pyridine-2-carbohydrazide leading to the desired 6-chlorothieno[3,2-c]pyridine-2-carbohydrazide-hydrazone derivatives (7a-r). The structure of the derivatives was characterized by elemental analysis, NMR, infrared and mass spectroscopic analysis. These compounds were screened for their antibacterial property towards Gram positive and Gram negative bacterial strains using agar diffusion method with reference to norfloxacin as reference antibiotic.
Studies and Synthesis of Substituted 4-Biphenyl Acetamide Derivatives
Authors: Khullar Anju
Published: February 2019

A new series of substituted 4-biphenylamides have been synthesized by condensation of 4-biphenyl acetic acid with different primary amines (aromatic and aliphatic). 4-Biphenyl acetic acid was first treated with thionyl chloride in dry benzene to prepare substituted 4-biphenyl acetyl chloride, which is then treated with different aliphatic or aromatic amines to synthesize various substituted 4-biphenyl acid-amide derivatives. The structure of newly synthesized compounds has been established by analytical and spectral methods. These synthesized compounds have shown antifungal properties against Fusarium udum and Curvularia lunata.
A Precised Surface Modification of Hydroxyapatite with Poly(methylmethacrylate) for Tissue Engineering & Regenerative Medicine
Authors: Nguyen Trinh Duy , Nhan Nguyen Phu Thuong , Tran Thien Hien , Islam Md. Rafiqul , Lim Kwon Taek , Bach Long Giang
Published: February 2019

The poly(methylmethacrylate) (PMMA) grafted biocompatible hydroxyapatite nanocrystals (HAPs) hybrid nanocomposites (PMMA-g-HAPs) were synthesized by employing surface thiol-lactam initiated radical polymerization (TLIRP) through grafting from strategy. At first, the surface of HAPs was functionalized by 3-mercaptopropyl-trimethoxysilane in one-step process to prepare thiol immobilized HAPs (HAPs-SH). Subsequently, a controlled radical polymerization of MMA by using two component initiating system comprising of HAPs-SH and butyrolactam (BL) successfully afforded PMMA-g-HAPs nanocomposites. The resulting structure and morphological feature of nanocomposites was systematically characterized by FT-IR and XRD analyses. GPC studies of cleaved polymers from nanocomposites of different time revealed that the grafting polymerization from the surface of HAP was well controlled in nature. Moreover, the thermal property of the PMMA was found to be improved by incorporation of inorganic HAP nanoparticles in the polymer matrix as revealed by TGA and DSC studies. The colloidal stability of the synthesized nanocomposites was observed to be exceptionally good in organic solvents as suggested by the time dependent monitoring using UV-visible spectroscopy and captured digital photographs. The synthesized nanocomposites show a great promise for the safe application in tissue engineering and regenerative medicine.
A Mixture of Iodide Ion and Gum Exudates of Eucalyptus globules as Green Inhibitor for Dissolution Control of Mild Steel in 1 N HCl Medium
Authors: Dheenadhayalan S. , Roja R. , Nijarubini V. , Mallika J.
Published: February 2019

The mild steel dissolution in 1 N HCl medium was monitored in the presence and absence of gum exudates of Eucalyptus globles (GEG) using quantitative gravimetric method at 303-323 K. The synergistic influence of iodide ions with GEG on the dissolution of mild steel was also studied at 303-323 K. The impedance (Rct and Cdl) and polarization (ba, bc, icorr, Ecorr) parameters were obtained from electrochemical methods for the optimum concentration of GEG and GEG + I–. The dissolution of mild steel decreases with increase in the concentration of GEG and GEG + I– at 30 °C. But their inhibition ability of tested inhibitor system for dissolution control of mild steel decreases with increase in temperature but rate of dissolution of mild steel is comparatively less in the case of GEG + I–. Adsorption of GEG on mild steel obeys Langmuir’s isotherm and supports physisorption process. Tafel’s parameters confirm the mixed nature of the studied inhibitor.
Synthesis and Structural Investigation of Some Transition Metals Complexes of Benzimidazolium Bromide
Authors: Hasson Mohammed Mujbel , Awad Adil A. , Al-Jibouri Mahmoud Najim
Published: February 2019

The present work involves the synthesis of novel imidazolium salts of bromide in step-wise reactions which are started from preparation of 2,4-dimorpholine-6-(1H-benzimidazole-1-yl)-1,3,5-triazine (1) in potassium hydroxide and DMF solvent followed by substitution reactions with n-butyl bromide and n-octyl bromide to afford the new ligands names L1 = 1-(2,4-dimorpholino-1,3,5-triazine-2-yl)-3-butyl-1H-benzimidazol-3-ium bromide and L2 = 1-(2,4-dimorpholino-1,3,5-triazine-2-yl)-3-octyl-1Hbenimidazol-3-ium bromide. The new ligands were recrystallized from hot chloroform and the following of reactions completion were carried out by thin layer chromatography (TLC). The formula and structures of the two salts of benzimidazolium bromide were confirmed on the basis of measurements of (CHN) elemental analyses, FT-IR, NMR and EIMS spectroscopy. Furthermore the manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes were synthesized from the direct reactions of their hydrated metal salts in methanol with the solutions of the ligands in chloroform in 1:1 mole ratio and the analytical data of atomic absorption spectroscopy and elemental analyses revealed the proposed formula of the solid metal complexes. The data obtained from FT-IR, UV-Visible spectra, molar conductivity and magnetic susceptibility measurements confirmed the octahedral environment around cobalt(II) ion in [CoL(H2O)2Cl2] and the tetrahedral geometry was adopted for manganese(II) and zinc(II) ions. However the square-planner structure was expected for the copper(II) and nickel(II) complexes in [MLCl2], M = Ni(II) and Cu(II) ions and L = L1 and L2 ligands. As well as the suitable and favourable active sites in the two ligands L1 and L2 were the two nitrogen atoms of morpholine rings which has been observed from FT-IR spectra and the kinetic stability of five-member ring up on chelation with the metal ions supported the conclusion of the symmetry.
A 4-(1H-Benzo[d]oxazole-2-yl)-2-methoxyphenol as Dual Selective Sensor for Cyanide Ion Detection
Authors: Rahmawati R. , Purwono B. , Hadisaputera S.
Published: February 2019

A dual sensor based on benzoxazole containing moiety S3 was successfully synthesized and applied for detection of CN− ion. The S3 molecule changed its colour for dark brown to dark green on addition of the CN− ion only in DMSO solvent. The limit of detection (LOD) and association constant (Kass) values was 0.4 × 10−6 M and 1.0 × 107 M−1; and 0.46 × 10−4 M and 1.0 × 105 M−1 determined by UV-visible spectroscopic titration and fluorescence titration, respectively.
Removal of Selective Metal Ions from Water with Hydroxy Propyl Cellulose Hydrogel
Authors: Devi Ch. Shanti , Devi S. Manimukta , Singh N. Shubhaschandra
Published: February 2019

In this study, environmentally friendly hydrogels prepared from hydroxy propyl cellulose hydrogels blended with poly(vinyl alcohol) (PVA) and poly(vinyl pyrrolidone) (PVP) were employed to absorb selected metal ions of Cu and Fe to find potential applications in removal of metal ion from water or in wastewater treatment. Highest adsorption capacity of hydroxy propyl cellulose hydrogels blended with PVA or PVP is shown at 0.04 % (w/v) of the metal ion solutions. Hydroxy propyl cellulose hydrogel when blended PVA has shown greater adsorption of Fe(III) ion than Cu(II) ion at higher pH. Hydroxy propyl cellulose hydrogel when blended with PVP also showed maximum adsorption capacity rather than PVA blended hydrogel.
Analysis of Antinutritional Components of Oil and Meal in Different Provenances of Jatropha curcas from India
Authors: Pradhan Subhalaxmi , Pradhan Gitanjali , Naik S.N.
Published: February 2019

The present work describes the estimation of antinutritional components such as phorbol esters in oil, trypsin inhibitors and phytates in the defatted meal of Jatropha curcas seeds collected from different geographical locations of India. The phorbol ester, trypsin inhibitor and phytate content in the defatted seed meal were extracted and estimated. Phorbol esters, the major toxic components vary from 0.9 to 3.2 mg/g in oil and 0.2 to 1.6 mg/g in the defatted meal. Similarly, a wide variation was observed for trypsin inhibitor (5.72-23.09 mg/g of defatted seed meal) and phytate (7.9-10.1 %) content in the meal of seeds collected from different geographical locations of India. The study also examined the variation of concentration of antinutritional components with the effect of meteorological parameters mainly climatological temperature and rainfall over stations. The phorbol esters content in the seed and meal are increased/decreased from region to region with the subsequent variation of temperature and rainfall. A similar trend is also observed in variation of trypsin inhibitors in seed cake whereas the variation of phytate concentration is not correlated with rainfall and temperature.
Synthesis and Characterization of Some Useful Thermoelectric Materials
Authors: Singh Jaspal , Verma S.S.
Published: February 2019

This paper aims to introduce the synthesis and characterization of some useful thermo electric pellets in order to determine their ability to convert waste heat into electricity. The thermo electric pellets of Bi2Pb3, Bi2Te3 and Pb2Te3 in cylindrical dimensions are prepared by 15 mm mixture of different compositions. The research work explores the facts that how such kind of the semiconducting materials can be utilized as thermo-electric power generation elements. The performance of these pellets analyzed not only in the normal mode but also under the effect of electric and magnetic fields, which can exist already or applied in the condition of their operation. Thermo-emf generation is carried out in the normal mode and under the influence of applied electric and magnetic fields of different magnitudes in the temperature range of 190 °C. Hence, the paper is an outlet of the waste heat utilization with the influence of electric or magnetic field towards their conversion of waste heat into electricity by special sized thermoelectric pellets and the suitable chemical method of their preparation.
Green Synthesis, Characterization and Antimicrobial Activity of Zinc Oxide Nanoparticles Using Root Extract of Viola canescens Wall. ex. Roxb.
Authors: Khajuria Arun Kumar , Negi Abha , Bisht N.S. , Maurya V. , Kandwal Anuj
Published: February 2019

Stable zinc oxide nanoparticles were synthesized by using green approach of nanotechnology. The present investigation aimed to synthesize, stable, cost effective, rapid, eco-friendly approach for the bio-reduction of zinc nitrate hexahydarate to their nano size using phytochemicals present in the root extract of Viola canescens. The synthesized nanoparticles were further characterized by UV-visible, XRD, FTIR, SEM techniques and tested against the Gram-negative and Gram-positive pathogenic cultures of bacteria. The average size of synthesized nanoparticles was less than 11 nm with hexagonal morphology. The clear zone of inhibition against tested bacteria showed their capability as antimicrobial agent.
Green Synthesis of Copper Nanoparticles: Evaluation of Catalytic and Antibacterial Activity
Authors: Reddeppa M. , Krishna Reddy R. Chenna , Raj Y. Paul , Rani T. Shobha
Published: February 2019

The objective of present study is to synthesize copper nanoparticles from Vitex negundo Linn., root bark extract as reducing and stabilizing agents. The synthesized nanoparticles were characterized by using UV-visible spectrophotometer, X-ray diffraction, FTIR, SEM and EDX. The results were shown that copper nanoparticles exhibited UV-visible absorption peak at around 550 nm. The XRD study confirmed that nanoparticles are crystalline in nature. In addition to these, FTIR was also used to analyze the various functional groups stabilized and protected the copper nanoparticles. The SEM results revealed that the copper nanoparticles are spherical, cubic and hexagonal in shape and having the particle size ranging from 40 to 60 nm. Catalytic activity of copper nanoparticles were studied in the Huisgen [3+2] cycloaddition of azides and alkynes to obtain 1,4-disubstituted 1,2,3-triazole at room temperature. Antibacterial profile revealed that the biopotent copper nanoparticles exhibited moderate to good activity against bacterial strains.
in silico Approach Towards Antiinflammation and Anticancer Studies on Phytoconstituents Derived from Cissus quadrangularis
Authors: Edathil Vidya , Selvi Gopal
Published: February 2019

Ethanobotanical and traditional uses of plant Cissus quadrangularis has initiated the phytochemical investigation of the plant. The stem of the plant was subjected for successive solvent extraction with petroleum ether, ethyl acetate, chloroform and ethanol. The crude extract were column choromatographed. Among 20 constituents isolated ascorbic acid, quercetin, phytol and luteol were identified. Later those phytochemicals were subjected for molecular docking in Autodock 4.2 to examine their pharmacological activity. The results obtained showed that these compounds can be further carry over for in vivo analysis.
Physico-Chemical Analysis on Some Polymers in Aqueous Surfactant Solution at Different Temperatures: Acoustical, UV and FTIR Studies
Authors: Chithralekha N. , Panneerselvam A.
Published: February 2019

The ultrasonic velocity, density and viscosity in mixtures of sorbitan sesquioleate and poly(vinyl pyrrolidone) (PVP), poly(vinyl alcohol) (PVA) and poly(ethylene glycol) (PEG) in different concentration ranges are measured at different temperatures (303, 313 and 323 K). From the experimental data, other related acoustical parameters such as adiabatic compressibility (β), intermolecular free length (Lf), internal pressure (πi), Rao’s constant (Ra), relaxation time (τ), acoustical impedance (Za), absorption coefficient (α/f2), free volume (Vf), cohesive energy (CE) and solvation number (Sn) have been evaluated. In aqueous solutions, surfactant molecule starts to aggregate and form micelle in concentration called as critical micelle concentration (CMC). It is one of the most important physical parameters of the surfactants. These results were interpreted in terms of surfactantpolymer complex reactions. The combinations of surfactant with polymers improve the desired properties of the product and the formation of complex was confirmed by UV and FTIR studies.