bluuebunny/crossref_metadata_2025 huggingface dataset:
Features of the diagnosis of Gaucher disease in children in the Russian Federation
Authors: Movsisyan G. B. , Surkov A. N. , Namazova-Baranova L. S. , Savostyanov K. V.
Published: July 2020

Relevance. Diagnostic algorithms are an effective tool for the early detection and proper monitoring of patients with a rare pathology.

The purpose of the study was to study the epidemiological, medical history, clinical and laboratory features of Gaucher disease (GD) in children in the Russian Federation (RF) to improve the algorithm for its diagnosis in a pediatric cohort of patients.

Materials and methods. A retrospective study of data on children with GD included in the pediatric registry of National Health Medical Research Center for Children of the Ministry of Health of Russia was conducted. The data recording period is from 2006 to 2016.

Results. The database contains 115 children with GD. The prevalence of the disease was 0.32 per 100 thousand children, with predominance in the Ural and North Caucasian federal districts. Only in 25 % of patients the diagnosis is confirmed within 6 months of the initial treatment. The family nature of the symptoms is established in 22 % of cases. Clinical polymorphism of GD leads to an erroneous interpretation of the diagnosis at primary reversibility in 85 % of cases; unjustified diagnostic and therapeutic measures, including surgical ones, in 70 % and 50 % of cases, respectively, thus leading to a delay in establishing the correct diagnosis up to 3.5 years and prescribing adequate treatment up to 4 years from the date of the examination. Key parameters for diagnosing GD include: damage to the parenchymal organs in the form of splenomegaly in 100 % and hepatomegaly in 94.8 % of patients; a change in hematological parameters in the form of anemia in 86.1 % and thrombocytopenia in 91.3 %; a change in biomarkers in the form of an increase in chitotriosidase activities in 94.0 % and aspartate aminotransferase in 51.0 %; ferritin concentration in 70.6 %, against a background of a decrease in iron content in 60.5 % and lipid metabolism (cholesterol in 54.0 % and high density lipoproteids in 85.0 %); elongation in the coagulogram of activated partial thromboplastin time in 66.2 % and prothrombotic time in 51.6 %; pathology of the skeletal system in the form of chronic bone pain and bone crises in 43 % and 18 % of patients, respectively; limb deformity of the type of “Erlenmeyer flasks” on the radiograph in 55.6 %; involvement of the central nervous system in patients with type II and type III hypertension in the form of oculomotor apraxia in 100 % of cases. An improved algorithm for diagnosing GD in children is proposed.

Conclusion. Optimization of the algorithm for diagnosing GD in pediatrics will improve the provision of medical care to children with this orphan pathology in the RF.
Synthesis, Characterization and Antibacterial Evaluation of 2, 3Dihydroquinazolin-4 (1H)-Ones and Some New Bis 2, 3- Dihydroquinazolin-4 (1H)-Ones Using Pre-made Pyrazole Carbaldehyde Derivatives
Authors: Sina Kiana Faraji , Yahyazadeh Asieh , Mahmoodi Nosrat Ollah
Published: July 2020

2, 3-Dihydroquinazolinones are of popular compounds with the diversification of biological
and pharmacological activities. Among many discovered methods, there are efficient and convenient
methods used for the synthesis of 2, 3-dihydroquinazoline-4 (1H)-one and some new bis 2, 3-
dihydroquinazoline-4 (1H)-one derivatives which are reported in this study. The mentioned methods
include the two-component condensation of one molecule of anthranilamide and one molecule of pyrazole
carbaldehyde using montmorillonite-K10 as a catalyst for the preparation of 2, 3
dihydroquinazoline-
4 (1H)-ones. Also, one-pot pseudo-five-component reaction (5MCRs) of two molecules of isatoic
anhydride, two molecules of pyrazole carbaldehydes and one molecule of ethan-1, 2-diamine in the
presence of the r catalyst (montmorillonite-K10) for the synthesis of bis 2, 3-dihydroquinazoline-4
(1H)-ones. Despite the short times of reactions, high yields of products were obtained, which were validated
using FT-IR, 1HNMR, 13CNMR, and elemental analysis. Moreover, the compounds were
screened for their antimicrobial activities against two-gram-positive bacterial strains: Staphylococcus
aureus and Micrococcus Luteus; and against two-gram-negative bacterial strains, as well: Escherichia
coli and Pseudomonas aeruginosa, which all were utilized for antibacterial investigations. The results
showed moderate or significant antibacterial activities.
Recent Advances in Synthesis of Benzoxazole
Authors: Bansal Shivani
Published: July 2020

Benzoxazoles are an important class of the heterocyclic compound and display a wide
range of pharmacological activities and other applications. Due to their varied application, they are
always an important moiety for synthetic chemists to develop newer methodologies for their synthesis.
In this review, an attempt has been made to briefly describe and summarize all of the available
methods for the preparation of benzoxazoles, and their substitutes as well as also discuss their functionlization.
Understanding the Pathogenesis Involved in Parkinson’s Disease and Potential Therapeutic Treatment Strategies
Authors: Dhanawat Meenakshi , Mehta Dinesh K. , Gupta Sumeet , Das Rina
Published: July 2020

:

A vast advancement has been made in the treatment related to central nervous system
disorders especially Parkinson’s disease. The development in therapeutics and a better understanding
of the targets results in upsurge of many promising therapies for Parkinson’s disease. Parkinson’s
disease is defined by neuronal degeneration and neuroinflammation and it is reported that
the presence of the neurofibrillary aggregates such as Lewy bodies is considered as the marker.
Along with this, it is also characterized by the presence of motor and non-motor symptoms, as
seen in Parkinsonian patients. A lot of treatment options mainly focus on prophylactic measures or
the symptomatic treatment of Parkinson’s disease.

:

Neuroinflammation and neurodegeneration are the point of interest which can be exploited as a
new target to emphasis on Parkinson’s disease.

:

A thorough study of these targets helps in modifications of those molecules which are particularly
involved in causing the neuronal degeneration and neuroinflammation in Parkinson’s disease.

:

A lot of drug regimens are available for the treatment of Parkinson’s disease, although levodopa
remains the choice of drug for controlling the symptoms, yet is accompanied with significant
snags. It is always suggested to use other drug therapies concomitantly with levodopa.

:

A number of significant causes and therapeutic targets for Parkinson’s disease have been identified
in the last decade, here an attempt was made to highlight the most significant of them. It was
also found that the treatment regimen and involvement of therapies are totally dependent on individuals
and can be tailored to the needs of each individual patient.
A brief description of the foam concrete: its properties, advantages and disadvantages: review
Authors: Hamada Ruqaya F. , Hameed Awham M.
Published: July 2020

:

The foam concrete has many advantages when compared to conventional concrete such as advanced strength to
weight ratio as well as the material for energy-saving construction. This concrete has broadly been utilized in the
constructing manufacturing. The current work presents an appraisal of foamed concrete ingredients, fabricating methods,
as well as the foamed concrete features. Furthermore, this literature appraisal aims for providing a complete vision about
the tests, including compressive strength, density, porosity, splitting tensile strength and water absorption of foamed
concrete. Also, this paper focuses to study the development and applications of the foam concrete. The advantages and
disadvantages of this type of concrete were presented in details through this article.
Sustainability Failure in the Antimicrobial Stewardship Program in a Secondary Care Hospital from Cuba: A Historical Review of 30 Years and 3 Shots
Authors: Garcell Humberto G. , Socias Juan J.P. , Gómez Gilberto P.
Published: July 2020

Background:

During the last 30 years, an Antimicrobial Stewardship Program (ASP)
was implemented in a facility with periods of weakness. We aim to describe the history of sustainability
failure in the local ASP.

Methods:

A historical review was conducted using original data from the facility library and papers
published. An analysis of factors related to the failure was conducted based on the Doyle approach.

Results:

The first ASP was implemented from 1989 to 1996 based on the international experiences
and contributed to the improvement in the quality of prescription, reduction of 52% in cost and in
the incidence of nosocomial infection. The second program restarted in 2008 and declined in 2015,
while, the third program was guided by the Pan-American Health Organization from 2019. This
program, in progress, is more comprehensive than previous ones and introduced as a novel measure
the monitoring of antibiotic prophylaxis in surgery. The factors related to the sustainability
were considered including the availability of antimicrobials, the leader´s support, safety culture,
and infrastructure.

Conclusions:

The history behind thirty years of experiences in antimicrobial stewardship programs
has allowed us to identify the gaps that require proactive strategies and actions to achieve sustainability
and continuous quality improvement.
Environmentally Benign PEG-OSO3H-Catalysed Ultrasound Promoted Cascade Synthesis of Furocoumarins in Water
Authors: Wagare Devendra , Shaikh Mujahed , Lingampalle Dinesh , Durrani Ayesha
Published: July 2020

Background:

For the green synthesis of furocoumarins in water, PEG-OSO3H was used as a
recyclable catalyst for the one-pot synthesis in water. To avoid the use of toxic lachrymators and unstable
phenacyl bromides, we prepared them in-situ and directly condensed with 4-hydroxycoumarins.

Objective:

PEG-OSO3H was found to be an efficient and reusable catalyst for the microwave irradiated
one-pot synthesis of 3-Aryl-furo[3,2-c]coumarins in PEG-water as a greener reaction medium. This
method was found to be rapid, simple, eco-friendly and obtained relatively higher yield than other reported
methods.

Methods:

Aromatic ketones (5 mmol), NBS (5mmol) were added in the solution of PEG-OSO3H (10
mol%) in 10 ml water and irradiated under ultrasound at 80-85°C. Then, the solution of 4-
hydroxycoumarin (5 mmol) and the solution of acetic acid and ammonium acetate (1 ml) were added
into it. The reaction mass was further irradiated for 3 min. From the reaction mixture, ethyl acetate (3 x
10ml) was extracted and the combined ethyl acetate phase was concentrated under reduced pressure to
obtain corresponding 3-Aryl-furo[3,2-c]coumarins. The aqueous layer was reused for the next reactions.

Results:

It was observed that electrons withdrawing groups (-NO2,-F etc.) on the benzene ring of aromatic
ketones increased the rate of reactions as well as the yield of the products. The IR spectrum of
compound 4a showed prominent peaks at 1737cm-1C=O stretching for lactone. 1H NMR of compound
4c showed characteristic singlets for –CH3 of methoxy group at 3.94 ppm. The above spectral data
confirmed the structure of the compound. The 13C NMR spectrum of 4b also showed the peaks of
CH3, at 23.25 ppm.

Conclusion:

PEG-OSO3H has been found to be an efficient and reusable catalyst for the microwave
irradiated one-pot synthesis of 3-Aryl-furo[3,2-c]coumarins in PEG-water as a greener reaction medium.
This method found to be rapid, simple, eco-friendly and obtained relatively higher yield than other
reported methods.
Select main parameters of Internet traffic exchange network
Authors: Chechin G. V.
Published: July 2020

The article considers the urgent problem of mathematical modeling of the Internet traffic exchange network. A mathematical model of an Internet traffic exchange network with an arbitrary number IX (Internet Exchange Point, IX, IXP) in the form of a Queuing network is presented. The model allows you to analyze alternative options for building a traffic exchange network and determine the optimal parameters of its structure: minimize the average delay and select the bandwidth of communication channels, the performance of traffic exchange nodes with restrictions on reliability and cost, and select the topology of the traffic exchange network taking into account the main parameters. Calculation examples are provided for Internet traffic exchange networks with a uniformly growing and substantially uneven loading of channels. We conclude that it is advisable to build networks with several Internet traffic exchange nodes.
Synthesis of a packet of pulse with phase manipulation with side lobes level 1/N at incoherent accumulation
Authors: Korobeynikov A. V.
Published: July 2020

The paper is devoted to the problem of choosing a probing radar signal using optimal processing of a packet of pulses with unknown initial phases. A method for synthesizing a packet of phase-coded pulses is proposed, the total autocorrelation function (ACF) of which, with coordinated filtering and incoherent accumulation, has a side lobes level (SLL) of 1/N. The search criteria for binary codes for phase manipulation of a signal that are potentially capable of forming packets of pulses with relative SLL of 1/N are formulated and justified. An algorithm has been developed for searching codes with a given ACF using the exhaustive search method. A method is proposed for forming the composition of a packets of pulses based on the exhaustive search method. A number of values of the code N duration were determined for which there are packets of pulses with a relative SLL of the total ACF equal to 1/N with coordinated filtering and incoherent accumulation.
Experimental research of indoor navigation system based on broadcast signals
Authors: Ksendzuk A. V. , Surmin E. A. , Kachesov V. V. , Zhdanov S. O. , Shakhalov K. S.
Published: July 2020

Results of an experimental study of a local navigation system based on the processing signals from broadcast sources presented. The results of the development of processing algorithms for point-to-point coordinates estimation of the object are presented. The results of the development of algorithms for trajectories estimation are presented. In performed simulation the possibility of obtaining submeter position estimation accuracy in the proposed system is shown. Development results of the navigation module demonstrator are presented. The results of experimental work in difficult navigation conditions, in the presence of shading, reflections and other factors, are presented. It is shown that the developed navigation module allows in the open space near buildings which partially obscuring the satellite systems signals to obtain accuracy higher than the GNSS navigation equipment. In indoor environment in the absence of satellite navigation signals, the developed module shows positioning accuracy not worse than 1.5 meters and provides a measurement rate 1 Hz and better.
Simulation of echo signals of two-position radar station using matrix of five emitters
Authors: Sabitov T. I. , Kiselev A. V.
Published: July 2020

The problem of modeling the echo signals of radar systems which use two receiving antennas with spaced phase centers and overlapping beam patterns is considered. To solve it, it is proposed to use a matrix of five emitters. Its configuration is based on the results of the previous work of the authors and meets the conditions of compensation and orthogonality of signals. Independent simulation of targets for each antenna is carried out by two pairs of emitters, while the fifth one is introduced for phase compensation of signals. The orthogonality condition is met by configuring the radiation points. Relations are obtained for calculating the coordinates of the radiation points. It is shown that emitters can be located on one straight line. As an example, a matrix was synthesized for a given input data. It was tested by numerical simulation methods. The results of the experiment confirmed the validity of the results found.
Epiglottic retroversion in nine dogs
Authors: Van Ginneken K. , Van Goethem B. , Devriendt N. , Bosmans T. , De Rooster H.
Published: July 2020

Epiglottic retroversion (ER) is an uncommon and poorly understood disorder of the upper respiratory tract in small breed dogs. In this retrospective study, perioperative characteristics, surgical technique, outcome, and complications in nine dogs that underwent surgical treatment for ER and/or concurrent upper respiratory tract disorders, were evaluated. The most frequently reported clinical symptoms were chronic intermittent inspiratory stridor (89%), exercise intolerance (78%), and dyspnea (67%). Concurrent respiratory disorders were highly prevalent (78%). Five dogs initially underwent a temporary epiglottopexy and two a permanent epiglottopexy. In two dogs, both suffering from concurrent laryngeal paralysis, only a unilateral cricoarytenoid lateralization was performed. After initial clinical improvement, temporary and permanent epiglottopexy eventually failed in 4/6 dogs (67%) that were available for follow-up, necessitating partial epiglottectomy as revision surgery. This resulted in a successful long-term outcome in 5/6 of these dogs (83%). In the dogs with primary ER or in cases where the presence of secondary ER led to significant respiratory symptoms, partial epiglottectomy as a primary surgical technique appeared to be a more permanent treatment option than epiglottopexy. Both dogs with surgically corrected concurrent laryngeal paralysis without epiglottopexy or epiglottectomy showed clinical improvement. This might indicate that, in case of secondary ER, positive results can be achieved after management of the underlying respiratory disorder.
Putative paraneoplastic pemphigus in a dog: clinical and microscopic findings
Authors: Declercq J. , Declercq L. , Vercauteren G.
Published: July 2020

In this case report, a dog with clinical and histopathological features of paraneoplastic pemphigus is described. A Lhasa apso with severe ulcerative oral and predominant facial skin disease had a thoracic mass histopathologically diagnosed as a thymoma. A concurrent disease-association was suspected. Cytologic examination of the oral lesions provided early clues to the dog’s ulcerative condition.
‘Grave-Paved Stars’: Comparing the Death of Two Artists in Nineteenth-Century Rome
Authors: Lindsey Kiera
Published: July 2020

Adelaide Ironside (1831–1867) is best known as the ﬁrst Australian-born artist to train overseas. While her life offers a portal into Republican Sydney, Pre-Raphaelite London and Risorgimento Rome, the nature of her archive also highlights the limits of historical method and the need to employ what Virginia Woolf called ‘the biographer’s licence’ when researching and writing about subjects with problematic sources. In this article, I employ biographical license to contrast the better-known and better-documented death of the English poet John Keats (1795–1821), with the few records associated with Ironside’s death some forty years later, to speculate about the silences in her sources. There are several factors encouraging this approach. Both artists died in Rome of pulmonary tuberculosis. Both were patients of the famous doctor, Sir James Clark (1788–1870), and both died during winter in the care of the person with whom they are now buried. By situating Ironside within these broader nineteenth-century contexts, my biographical subject evolves from a shadowy historical representative of demographic and an era into a ﬁgure who is more ﬂesh and blood than an accocount focused upon her accomplishments and acquaintances might otherwise allow.
An Oracle of Ashes: The Burial of James Purdy
Authors: Holt Maria Cecilia
Published: July 2020

James Purdy (b. 1914), an American writer known for his grim humour and embrace of the outlandish and estranged, died in 2009, shortly after uttering his final wish: that after cremation his ashes should be buried near to Dame Edith Sitwell, one of the earliest and staunchest supporters of his works. This essay chronicles the journey of Purdy’s ashes from New York, USA, to Northamptonshire, UK, where they were laid to rest ten years after his death, and it explains how the present writer came to know Purdy not only through his novels, plays and poems, but also through working with Purdy’s literary executor, John Uecker, who also served as an assistant to Tennessee Williams. Necessarily autobiographical in certain passages, this essay tells of the discovery of grief in the process of planning the burial, of the power that can inhere in the materiality of cremated remains, and of the legal and logistical complexities of plotting interment across international borders.
Mobilizing Grief and Remembrance with and for Networked Publics: towards a Typology of Hyper-Mourning
Authors: Giaxoglou Korina
Published: July 2020

The past decade has seen an intense mobilization of grief and remembrance on social media linked to the injunction to inscribe, share, and curate life and death in the here-and-now. This article navigates the heterogeneity of these practices, using the term hyper-mourning to point both to the conditioning of mourning by the affordances of hyper-connectivity and to debates around these emerging forms of mourning as being emotionally hyperbolic and ‘inauthentic’ reactions to death events. Based on the discussion of select examples, I sketch out a typology of hyper-mourning, depending on the different story positions of teller, co-teller, or witness from which such performances are produced. As I argue, these different performances become typically associated with particular modes of affective positioning made available to the recipients of these shared stories—namely positions of proximity or distance to the death event and the dead, the networked recipient(s), and the emotional self. This typology proposes a small stories approach to hyper-mourning practices, which are organized around the mobilization of grief and remembrance for connecting networked audiences around identities, affect, and moral values dis/alignments. The article contributes to the interdisciplinary study of digital cultures of memory, affect, and identities.
FINIS: Objects of the End of Time, Afterlife Writing and Situation of Graves
Authors: Wildgoose Jane
Published: July 2020

Focusing on Hogarth’s last graphic work, The Bathos, this essay examines the ways in which the vanitas themes it represents are bound up with events that occurred towards the end of the artist’s life. Drawing on life writing (including elements of Hogarth’s autobiographical notes) that accompanied the cataloguing of his works in the years following his death, it discusses a number of controversies that drew scathing criticism of his work, his character, his politics, his ideas about English art and his standing as an artist, during his final years. Focusing on textual and visual images employed by Hogarth’s detractors to belittle him, it explores how these metaphors may be connected with the iconography he employed in The Bathos, and the extent to which the work may be ‘read’ as a representation of the artist himself, and his view of his reputation at the end of his career. Contrasting the pessimistic image Hogarth presents in his final work with the afterlife writing of his achievements by his contemporaries, it concludes with reflection on the role that his grave continues to play in celebrating his life and his status as one of the most talented and innovative artists of the eighteenth century.
Afterlife Writing and Situation of Graves II
Authors: Wildgoose Jane
Published: July 2020

This article discusses my practice as an artist and researcher examining the situation and significance of graves. First, in a site-specific installation at West Norwood Cemetery in South London, talking with visitors about whether it matters where human remains are deposited; secondly, in exhibitions at the Crypt Gallery St. Pancras and Lumen Crypt Gallery in Bethnal Green, presenting evidence of the historical circumstances in which human remains were appropriated from graves in the colonies, for the purposes of research into racial ‘science’ in museums during the late nineteenth century.
Life After Life
Authors: Giaxoglou Korina
Published: July 2020

This poem is a creative response to Oreet Ashery’s web-series Revisiting Genesis (2016) on show at Wellcome Collection between 30 May 2019 and 26 January 2020 as part of the exhibition Misbehaving Bodies: Jo Spence and Oreet Ashery (https://wellcomecollection.org/exhibitions/XFHHShUAAAU_pE70). The web-series is also available at http://revisitinggenesis.net. Quotation marks indicate snippets from the web-series.
Confronting Mental Disorder in Urban Physical Setting
Authors: Marzukhi Marlyana Azyyati , Ghazali Nur Masyitah , Ling Oliver Hoon Leh , Nasrudin Na’asah
Published: July 2020

Mental health issues have many causes, including the changing and unpredictable elements of the urban physical setting. Thus, this research is crucial to understand the mental health challenges of the urban population in Malaysia. Therefore, the objective of this research is to assess the magnitude of mental health outcomes and associated factors of the urban physical setting among the urban population. A study was carried out at two low-cost flats in Lembah Pantai, Kuala Lumpur, with a sample size of 102 respondents. The findings show that there is a correlation between the urban physical environment setting, particularly green spaces with mental disorders (depression, anxiety, and stress).    Keywords: urban planning; environment; mental; health.    eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.    DOI:
Developing the Rural Town of Panchor into a Future River-based Tourism Destination: Host Community Perception
Authors: Saad Mazni , Abdullah Nur Nabilah , Rosman Siti Nur Hidayah
Published: July 2020

This paper examines the significance of a rural area, Panchor village town, as a potential nature tourism site in the Muar district of Johor, Malaysia. The objectives of the study were (1) to evaluate local community support and (2) to assess local community involvement. Based on qualitative analysis of an interview and open-ended responses in the questionnaire, three interconnected themes were: (1) community attachment, (2) economic gains and (3) environmental attitude. The findings revealed that river-based tourism development could stimulate the socio-economic status and the sustainability of rural areas. This study also discussed implications and limitations of the research.   
Keywords: Community Attachment; Economic Gains; Environmental Attitude; River-based Tourism
eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bsby e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, UniversitiTeknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v5i14.2236
Intention to use Medical Apps Among Older Adults in the Netherlands: Cross-Sectional Study
Authors: Askari Marjan , Klaver Nicky Sabine , van Gestel Thimon Johannes , van de Klundert Joris
Published: July 2020

Background

The increasing health service demand driven by the aging of the global population calls for the development of modes of health service delivery that are less human resource–intensive. Electronic health (eHealth) and medical apps are expected to play an important role in this development. Although evidence shows mobile medical apps might be effective in improving the care, self-management, self-efficacy, health-related behavior, and medication adherence of older adults, little is known about older adults’ intention to use these technologies when needed, or the factors influencing this intention.

Objective

The objective of this study was to investigate the relationship of technology acceptance factors and intention to use mobile medical apps among community-dwelling older adults.

Methods

Data was collected using questionnaires. The factors selected from the literature have been validated using Cronbach α and tested for significance using logistic regressions.

Results

Almost half (49.7%) of the included older adults reported no intention to use medical apps. Adjusted logistic regression analysis per factor showed that the factors Attitude toward use (odds ratio [OR] 8.50), Perceived usefulness (OR 5.25), Perceived ease of use (OR 4.22), Service availability (OR 3.46), Sense of control (OR 3.40), Self-perceived effectiveness (OR 2.69), Facilities (OR 2.45), Personal innovativeness (OR 2.08), Social relationships (OR 1.79), Subjective norm (OR 1.48), and Feelings of anxiety (OR 0.62) significantly influenced the intention to use mobile medical apps among older adults, whereas the factor Finance (OR 0.98) did not. When considered together, a controlled multivariate logistic regression yielded high explained variances of 0.542 (Cox-Snell R2) and 0.728 (Nagelkerke R2).

Conclusions

The high odds ratios and explained variance indicate that the factors associated with the intention to use medical apps are largely understood and the most important factors have been identified. To advance the evidence base, experimental controlled research should investigate the causality between the factors, intention to use, and actual use. For this purpose, our evidence suggests that policies designed to improve Attitude toward use appear most effective, followed by policies addressing Perceived usefulness, Perceived ease of use, Service availability, and Sense of control.
Effects of the Interactive Web-Based Video “Mon Coeur, Mon BASIC” on Drug Adherence of Patients With Myocardial Infarction: Randomized Controlled Trial (Preprint)
Authors: Bruggmann Christel , Adjedj Julien , Sardy Sylvain , Muller Olivier , Voirol Pierre , Sadeghipour Farshid
Published: July 2020

BACKGROUND

Secondary prevention strategies after acute coronary syndrome (ACS) presentation with the use of drug combinations are essential to reduce the recurrence of cardiovascular events. However, lack of drug adherence is known to be common in this population and to be related to treatment failure. To improve drug adherence, we developed the “Mon Coeur, Mon BASIC” video. This online video has been specifically designed to inform patients about their disease and their current medications. Interactivity has been used to increase patient attention, and the video can also be viewed on smartphones and tablets.

OBJECTIVE

The objective of this study was to assess the long-term impact of an informative web-based video on drug adherence in patients admitted for an ACS.

METHODS

This randomized study was conducted with consecutive patients admitted to University Hospital of Lausanne for ACS. We randomized patients to an intervention group, which had access to the web-based video and a short interview with the pharmacist, and a control group receiving usual care. The primary outcome was the difference in drug adherence, assessed with the Adherence to Refills and Medication Scale (ARMS; 9 multiple-choice questions, scores ranging from 12 for perfect adherence to 48 for lack of adherence), between groups at 1, 3, and 6 months. We assessed the difference in ARMS score between both groups with the Wilcoxon rank sum test. Secondary outcomes were differences in knowledge, readmissions, and emergency room visits between groups and patients’ satisfaction with the video.

RESULTS

Sixty patients were included at baseline. The median age of the participants was 59 years (IQR 49-69), and 85% (51/60) were male. At 1 month, 51 patients participated in the follow-up, 50 patients participated at 3 months, and 47 patients participated at 6 months. The mean ARMS scores at 1 and 6 months did not differ between the intervention and control groups (13.24 vs 13.15, 13.52 vs 13.68, respectively). At 3 months, this score was significantly lower in the intervention group than in the control group (12.54 vs 13.75; P=.03). We observed significant increases in knowledge from baseline to 1 and 3 months, but not to 6 months, in the intervention group. Readmissions and emergency room visits have been very rare, and the proportion was not different among groups. Patients in the intervention group were highly satisfied with the video.

CONCLUSIONS

Despite a lower sample size than we expected to reach, we observed that the “Mon Coeur, Mon BASIC” web-based interactive video improved patients’ knowledge and seemed to have an impact on drug adherence. These results are encouraging, and the video will be offered to all patients admitted to our hospital with ACS.

CLINICALTRIAL

ClinicalTrials.gov NCT03949608; https://clinicaltrials.gov/ct2/show/NCT03949608
Analisis Finansial Perkebunan Kayuputih Skala Kecil: Studi Kasus Pilot Project Pengembangan Kayuputih untuk Kelompok Tani di Kampung Rimbajaya, Distrik Biak Timur
Authors: Prastyono Prastyono , Kartikawati Noor Khomsah , Sumardi Sumardi , Rimbawanto Anto
Published: July 2020

Produksi minyak kayuputih dari Kepulauan Maluku dan Pulau Jawa saat ini masih jauh di bawah permintaan kayuputih dalam negeri. Ekstensifikasi perkebunan kayuputih skala kecil yang  dikelola oleh masyarakat dengan menggunakan benih unggul dapat menjadi solusi untuk meningkatakan produksi minyak kayuputih di Indonesia. Tulisan ini dimaksudkan untuk mengetahui tingkat kelayakan finansial dari usaha perkebunan kayuputih skala kecil dengan menggunakan data dari pilot project pengembangan industri kayuputih skala kecil di Kampung Rimbajaya, Distrik Biak Timur seluas 5 ha. Kelayakan finansial dilihat dari kriteria investasi yang umum digunakan yaitu net present value (NPV), internal rate of return (IRR), benefit-cost ratio (BCR) dan payback period. Hasil analisis finansial menunjukkan bahwa kebun kayuputih unggul skala kecil layak untuk diusahakan dengan NPV untuk jangka waktu 25 tahun pada discount rate 9,2% adalah sebesar Rp 757.171.972,00 (Rp 151.434.394,32 per hektar), IRR sebesar 72,74%, BCR sebesar 1,77 dan payback period setelah 2 tahun 3 bulan. Secara finansial perkebunan kayuputih yang menggunakan benih unggul lebih layak diusahakan dibandingkan dengan komoditas bambu, sengon, sawit dan kopi. Financial Analysis of a Small Scale Cajuput Plantation: A Case Study of A Pilot Project for A Farmer Group in Rimbajaya Village, East Biak DistrictAbstractProduction of cajuput oil from the Moluccas and Java Island is currently far below the domestic demand for the oil. Extensification of small-scale cajuput plantations managed by community using improved seeds is expected to increase cajuput oil production inIndonesia. This study investigates the financial feasibility of a 5 ha-cajuput plantation using data collected from a pilot project for a farmer group in Rimbajaya Village, East Biak District. Financial feasibility was assessed by calculating four investment criteria: netpresent value (NPV), internal rate of return (IRR), benefit-cost ratio (BCR) and payback period. The analysis showed that a small-scale cajuput plantation was financially feasible with NPV (25 years) at a 9.2% discount rate was IDR 687,583,363.00 (IDR 137,516,672.63 per hectare), IRR of 66.5%, BCR of 1.70 and payback period after 2 years and 3 months. Investation in a cajuput plantation planted with improved seeds is more feasible than that in bamboo, sengon, palm oil and coffee plantations.
Peranan Semut di Ekosistem Transformasi Hutan Hujan Tropis Dataran Rendah
Authors: Haneda Noor Farikhah , Yuniar Nisfi
Published: July 2020

Deforestasi atau perubahan fungsi dari hutan menjadi non-hutan berperan dalam perubahan ekosistem dan spesies di dalamnya. Serangga sebagai salah satu fauna di dalamnya merupakan aspek yang menarik untuk dikaji khususnya semut. Tujuan penelitian ini adalah mengidentifikasi peranan-peranan dari genus semut yang ditemukan di ekosistem transformasi. Penelitian dilaksanakan di Desa Bungku, Kecamatan Bajubang, Kabupaten Batanghari, Provinsi Jambi. Metode yang digunakan dalam penelitian ini adalah membuat plot pengamatan secara purposive sampling. Plot pengamatan dipasang di empat eksosistem hutan dengan jumlah masing - masing ekosistem sebanyak empat plot. Setiap plot memiliki lima sub plot yang tersebar di empat eksosistem hutan untuk pemasangan pitfall trap. Teknik pengambilan sampel semut menggunakan pitfall trap di empat ekosistem. Empat ekosistem tersebut yaitu hutan sekunder, perkebunan kelapa sawit, kebun karet, dan hutan karet. Hasil penelitian ditemukan sebanyak 33 genus dari 6 subfamili. Selanjutnya dari 33 genus dikelompokkan berdasarkan peranannya. Berdasarkan peranannya terdapat 46% pencari makan , 36% predator, 3% semut tentara, 3% pemakan bangkai, dan 3% lainnya (semut pemanen/pemetik, omnivora, predator, dan pemakan bangkai). Camponotus sebagai genus dominan memiliki peranan pencari makan, dan Pheidole mempunyai peranan sebagai penghancur biji dan sebagian lainnya adalah omnivora. The Role of Ants in Lowland Tropical Rainforest TransformationAbstractDeforestation or changes functions from forest to non-forest play a role in changing ecosystems and the species within them. Insect as one of the fauna is an interesting aspect to study, especially ants. Aims of this study is to identify the roles of the genus of ants that found in the transformation ecosystem. This study was conducted in Bungku Village, Bajubang District, Batanghari Regency, Jambi. Method used in this study is to make a plot of observation by purposive sampling. Ant sampling techniques use pitfall traps in four ecosystems i.e.. secondary forest, oil palm plantation,rubber plantation, and jungle rubber. This study found 33 genera from 6 subfamilies. Furthermore, 33 genera are grouped based on their roles, i.e. (1) 46% foragers, (2) 36% for predators, (3) 3% for army ants, (4) 3% for scavengers, and (5) 3% for others (harvesting ants, omnivores, predators and scavengers too). Camponotus as the dominant genus has a role for foragers, and Pheidole has a role as a seed destroyer and the other part is omnivorous.
The Problem and Adjustment of the Unbalanced Allocation of Compulsory Education Resources: Evidence from Chongqing
Authors: Yu Wang
Published: July 2020

In order to narrow the gap in compulsory education resource distribution among districts and counties, and promote equity in education among regions. This article analyzes the current situation and causes of the unbalanced allocation of compulsory education resources in Chongqing and proposes the existing problems. Through the use of statistical description and spatial autocorrelation methods to analyze the internal relations of related factors and variables. And on the basis of proving the existence of proximity, it analyzes the type and influence mechanism of regional aggregation in the process of unbalanced allocation of compulsory education resources. This article focuses on constructing the theory of non-equilibrium allocation of compulsory education resources in Chongqing, proposing the basic assumptions of compulsory education resource allocation research, analyzing the problems of spillover effect, convergence effect, demonstration effect, etc. The theoretical hypothesis of the unbalanced allocation of educational resources is empirically tested.
Presentación
Authors: Peschard Mariscal Jacqueline
Published: July 2020

La coordinadora del número 29 de la RMOP presenta los artículos y reseña dictaminados para la revista; resalta su importancia para conocimiento de las formas de comunicación actual y la opinión pública derivada de ella, tanto en México como América Latina y el mundo.
“Justin Trudeau—I Don’t Know Her”: An Analysis of Leadership Memes of Justin Trudeau
Authors: Lalancette Mireille , Small Tamara A.
Published: July 2020

Background An internet meme is a concept or idea that spreads online. This article focuses on memes chronicling Justin Trudeau’s leadership during his first year as prime minister.

Analysis By conceptualizing leadership memes and developing a methodology to analyze these memes, this empirical study reflects the approaches meme creators use, both visually and rhetorically, to convey political messages about leadership.

Conclusion and implications The main purpose of Justin Trudeau memes is denunciation. Leadership memes present an alternative discourse of politics, outside of controlled channels of the politician and the traditional media. There is little work on leadership memes. This article contributes to the literature by not only focusing on Canadian politics but also by providing a method for studying leadership memes.
Enabling Postmedia: Economists as the “Rock Stars” of Canadian Competition Law
Authors: Edge Marc
Published: July 2020

Background Canada is suffering a crisis in local news largely attributable to regulatory failure. Its largest newspaper chain, Postmedia Network, took over the second-largest chain in late 2014, and in early 2016 it merged the newsrooms at its duplicate dailies in four of Canada’s six largest cities. Parliamentary hearings on local media ensued, and a mid-2017 report recommended, among other things, changes to the Competition Actto more effectively deal with news media mergers and takeovers.

Analysis The Competition Bureau is dominated by economists who may lack sufficient grounding in media issues to effectively deal with mergers and takeovers in news industries.

Conclusion and implications Reform of the country’s Competition Act, which has been called for by successive federal media inquiries, is more urgently required than ever.
Should Climate Scientists Fly?
Authors: Goodwin Jean
Published: July 2020

I inquire into argument at the system level, exploring the controversy over whether climate scientists should fly. I document participants’ knowledge of a skeptical argument that because scientists fly, they cannot testify credibly about the climate emergency. I show how this argument has been managed by pro-climate action arguers, and how some climate scientists have developed parallel reasoning, articulating a sophisticated case why they will be more effective in the controversy if they fly less. Finally, I review some strategies arguers deploy to use the arguments of others against them. I argue that only by attending to argument-making at the system level can we understand how arguers come to know the resources for argument available in a controversy and to think strategically about how to use them. I call for more work on argument at the system level
Spanish press during Transit period
Authors: Trofimova Marina D.
Published: July 2020

This article analyzes the role of Spanish media systems in the transit period in Spain. By research of the Spanish massmedia systems of the late 70s - early 80s and their interaction with the government, have been identified the basic features of a role of the Spanish media systems in democratization of a society, and also reconstruction of the information system which has become diametrically opposed to the information system of the previous time.
Militia Counterinsurgency: Perspective on the Motivations of Civilian Joint Task Force Militia Participation in Northern Nigeria
Authors: Gana Modu Lawan
Published: July 2020

Since the year 2013, Nigeria’s northeastern region epicenter of the Boko Haram Islamist insurgency waging war for the establishment of an Islamic State has witnessed mass participation of people in a civil militia group. The militia group colloquially describing itself Civilian Joint Task Force (CJTF) was formed to combat the Boko Haram rebellion. Perhaps, the participation of the CJTF in the combating activities was reportedly influential in reducing the Boko Haram hostilities in most communities. Prior to the CJTF, the counterinsurgency approaches of the Nigerian governments’ Special Joint Task Force and the Multinational Joint Task Force of the Member States of Lake Chad Basin Commission was faced with lackadaisical performances. Whereas the CJTF was reportedly successful, however, the interrupted participation of the people despite the attendant human and material cost has risen suspicion among the population and the critical literature about the groups’ true motivation. This article, therefore, investigated the motivations of the CJTF in northeastern Nigeria. The study was conducted through a qualitative approach designed in a case study. The data was collected from thirteen informants from three groups - CJTF, Community Leaders and State/Local Government authorities. The technique of data collection is in-depth interviews and non-participant observation. The finding revealed personal incentive factors of monetary/material gains, and the futuristic interest of employability drives peoples’ participation. To address the economic interests of the CJTF and as a panacea to prevent the manifestation of the security threats associated with the CJTF group, the study recommends for the establishment of charity centers to receive contributions from well to do citizens to ameliorate the economic needs of the participants. The government should also propound strong legal mechanisms to regulate the activities of the CJTF militia.
Economic Factors Undermining National Security: Joint Defence Facility Pine Gap, Australia
Authors: Beck Marko
Published: July 2020

The article analyses Joint Defence Facility Pine Gap in Australia that is used by the United States to controls satellites pinpoint airstrikes around the world. The Joint Facility rises political controversy in Australia (especially after Edward Snowden’s revelations) as many doubt if it is in Australia’s best interests to contribute data for drone assassinations and targeting US nuclear weapons. Considering Australia’s policy towards Joint Defence Facility Pine Gap the author raises the question whether national security can be “outsourced” to save budget funds. The article concludes that in Australia it is noticeable that human intelligence potential in financial terms is less valued than some construction, manual jobs. Considering that Russia and China, which are in the focus of Pine Gap intelligence gathering do not outsource its national security and were more successful in preventing major information leaks, moreover in preventing major terrorist attacks on their soil, is indicating that national security should not be privatized.