bluuebunny/crossref_metadata_2025 huggingface dataset:
Transient Elastohydrodynamic Lubrication of Rough Contact Surface for Intermittent Motion
Authors: Abd alsamieh Mohamed Fahmy
Published: July 2022

The current study aims to study the characteristics of transient elastohydrodynamic lubrication of smooth and rough surface contacts subjected to intermittent motion for different inactive periods of motion and deceleration/acceleration periods to fulfill an identified need for such conjunction. In this case, the non-steady Reynolds’ equation, the film thickness equation with elastic deformation and taking into account the influence of surface roughness, and the load balance equation are simultaneously solved using the Newton-Raphson with Gauss-Seidel iterations method to determine the film profile and pressure distribution at various time steps. Surface contact of sinusoidal waves is presented with different amplitudes and wavelengths. The results indicated that surface waviness causes random oscillations in pressure and film profiles at different time steps. The greater the amplitude of the waviness, the more pressure and film profile variations occur. The magnitude of the pressure and film profile fluctuations becomes little noticeable as the wavelength of a wavy surface rises. The findings of this investigation also revealed that increasing the inactive duration for wavy surfaces results in zero minimum film thickness and surface contact. Squeezing action is ineffective in conveying loading capacity in this circumstance. The central and maximum pressure heights increase during the stop time interval as stop time increases. The centre film thickness increases at the end of the deceleration phase when the deceleration/acceleration period is reduced, but the minimum film thickness is unaffected. In fact, the minimum film thickness tends to be zero at the end of the deceleration phase, regardless of the deceleration/acceleration period. The central and maximum pressure increase during the stop time interval with the decrease of the deceleration/acceleration period. The difference between the results for smooth and wavy surface contacts is the appearance of fluctuations in film and pressure profiles, as well as the reduction of the film thickness and increase in pressure for the wavy surface when compared to contact with a smooth surface.
Carbon and natural fiber reinforced polymer hybrid composite: Processes, applications, and challenges
Authors: SHEWALE JITESH , Chandrashekhar Choudhari  , Anil Kumar Singh Bankoti
Published: July 2022

Composites have recently emerged as the ideal material for weight reduction in a wide range of technical applications. Hybrid composites offer special properties that enable them to meet a wide range of design objectives more efficiently and affordably than conventional composites. Natural fiber-based hybrid composites are also less damaging to the environment and have a reduced carbon footprint. The hybridization of natural fibres with synthetic fibres can substantially minimise the problems associated with natural fibre composites, since the advantages of one kind of fibre can outweigh the disadvantages of another. Several research have been carried out to investigate the different characteristics of carbon-natural fibre reinforced hybrid composites and to evaluate their suitability for a variety of technological applications. The objective of this work is to provide an overview of the materials and manufacturing processes currently utilised to fabricate carbon-natural fibre reinforced hybrid composites. This paper also attempts to discuss the reported mechanical, damping, and other characteristics of the resultant hybrid composites. This article provides a factual overview of the development accomplished so far in the field of hybrid composites constructed from carbon-natural fibres.
Mathematical modelling of boundary layer flow over a permeable and time-dependent shrinking sheet – A stability analysis
Authors: Tan J. G. , Lok Yian Yian , Pop I.
Published: July 2022

Micropolar fluid is one type of non-Newtonian fluid which consists of non-deformable spherical particles that suspended in viscous medium. In this paper, the problem of two-dimensional boundary layer flow over a permeable shrinking sheet with time dependent velocity in strong concentration micropolar fluid is studied theoretically. The mathematical model is governed by continuity, momentum and microrotation equations. Similarity variables are introduced so that, after performing the similarity transformation on the governing equations, the resulting system of nonlinear ordinary differential equations is then numerically solved using the program bvp4c in Matlab software. The effects of the micropolar material parameter, the unsteadiness parameter, the shrinking parameter and the mass suction parameter to the skin friction coefficient, velocity profiles and microrotation profiles are investigated. It is found that triple solutions exist for some values of the parameters that were considered. Based on the stability analysis that was performed, it showed that only two branches of solutions are categorized as stable, whereas one solution branch is unstable.
Modeling, analysis and PID controller implementation on suspension system for quarter vehicle model
Authors: Kumar Shailendra , Medhavi Amit , Kumar Raghuvir , P.K. Mall
Published: July 2022

The aim of this research is to acquire a mathematical model for the quarter vehicle model's passive and active suspension system and to build an active and passive suspension control for a quarter-vehicle model. The passive design of the suspension scheme is a compromise between vehicle handling capacity and passenger ride comfort. Passive suspension provides one of these two circumstances that conflict. Current car suspension systems use passive components only by using a coefficient of spring and damping with a fixed coefficient and two degrees of freedom. In the design and manufacture of cars, passenger comfort is a very significant parameter. The objective of the active suspension system is to enhance both the comfort of the ride and the handling of the highway by directly regulating the actuators of suspension power. In the active suspension system, the Proportional Integral Differential Controller (PID) method is applied. Various kinds of highway profiles and controllers such as P, PD, PI, and PID controllers evaluate the efficiency of the active suspension system comparing it with passive suspension scheme. This efficiency will be determined by using the MATLAB and SIMULINK to perform computer simulations.
Numerical study of hydrodynamic and thermal behavior of Al2O3/Water nanofluid and Al2O3-Cu/Water hybrid nanofluid in a confined impinging slot jet using two-phase mixed model
Authors: Izadikia Maryam , Mahdi Miralam , Mobini Kamran
Published: July 2022

This study utilizes the two-phase mixture model to conduct a numeric study of Al2O3/Water and Al2O3-Cu/Water (hybrid) nanofluid's hydrodynamic and thermal behavior in a laminar confined impinging slot jet in 50 ≤ Re ≤ 300 and nanoparticles volume fractions (NVF) ranging from 0 - 2%. This study considers various aspect ratios (H/W), including 2, 4, and 6, to investiate the confining effects. This paper gives a comparative analysis of nanofluids and hybrid nanofluids in terms of the parameters concerning the flow: Reynolds and local Nusselt number (Nux), average Nusselt number (Nuavg), flow lines' contour, and temperature distribution under similar geometric conditions and Reynolds number. In comparison with nanofluids, the hybrid nanofluids have higher local Nusselt number on the entire target surface, this advantage of hybrid nanofluid attribute to higher thermal conductivity of them. The average Nusselt numbers of nanofluids and hybrid nanofluids plotted at different Refor various aspect ratios(H/W=2,4), and the effect of aspect ratio and momentum are explained. Furthermore, pumping power of both fluid analysed for all nanoparticles volume fraction (0 - 2%) at different Reynolds number. The result shows that pumping power of hybrid nanofluid is higher than base fluid and nanofluid, because the dynamic viscosity of hybrid nanofluid is higher than base fluid (water) and nanofluid. Besides; the study identified some correlations in the hybrid nanofluids regarding the stagnation point and the average Nusselt numbers. Presumably, these correlations are valid under certain conditions: 50≤ Re ≤ 300, 2 ≤ H/W≤ 6, and volume fracture (0 - 2%).
Alimentación, posesión diabólica y exorcismo.
Authors: Castilla Corzo Felipe
Published: July 2022

El presente artículo analiza, por medio de un abordaje teórico las nociones de posesión diabólica, maleficio y exorcismo, hilándolos a través de historias de objetos ingeridos que han sido manipulados para causar daño a las personas. Partiendo de que el pecado original entró al hombre por medio de una manzana, se asevera que el consumo de objetos maldecidos pueden ser el puente a la entrada del mal al cuerpo. La discusión fue abordada a partir del análisis documental, en el que se exploran fuentes de sacerdotes y académicos que han tratado estas temáticas desde un enfoque técnico y empírico. Se concluye que la ingesta de alimentos o bebidas mezclados con maleficios pueden ser causales de posesión diabólica, y, que, por medio del sacramento del exorcismo, son expulsados estos objetos liberando a las personas de sus males espirituales.
Voluntad, libertad, libre albedrío y libertinaje.
Authors: Rodríguez Milagros Elena
Published: July 2022

Se trata de una investigación transmetódica transparadigmática compleja, con el objetivo complejo analizar los constructos voluntad, libertad, libre albedrío y libertinaje como necesidades ecosóficas urgentes. En la línea de investigación: transepistemologías de los conocimientos-saberes y transmetodologías transcomplejas; antigenealogía de las indagaciones modernistas-postmodernistas-coloniales; el sujeto investigador estar en primera persona redarguyendo, aportando con su sentipensar; más allá de las divisiones estáticas y reduccionistas. Con el transmétodo: la hermenéutica comprensiva, ecosófica y diatópica entramada rizomáticamente en los momentos analíticos, empíricos y propositivos. En el momento propositivo, más allá de conclusiones acabadas discernimos que aun cuando el pecado nos ha invadido no olvidemos la creación contada maravillosamente en el Génesis: es urgente y es esa una necesidad ecosófica: examinarnos a nosotros mismos, desentrañar el tipo de semilla que coexistimos. ¿Tenemos la libertad para tal misión cogitativa? Creo que sí, concibiendo que la filosofía no se separa de la teología, ni de la ciencia.
Runtime accuracy alterable approximate floatingpoint multipliers
Authors: Lu Mi
Published: July 2022

Modern systems demand high computational power within limited resources. Approximate computing is a promising approach to design arithmetic units with tight resources for error-tolerant applications such as image and signal processing and computer vision. A floating-point multiplier is one of the arithmetic units with the highest complexity in such applications. Designing a floating-point multiplier based on the approximate computing technique can reduce its complexity as well as increase performance and energy efficiency. However, an unknown error rate for upcoming input data is problematic to design appropriate approximate multipliers. The existing solution is to utilize an error estimator relying on statistical analysis. In this paper, we propose new approximate floating-point multipliers based on an accumulator and reconfigurable adders with an error estimator. Unlike previous designs, our proposed designs are able to change the levels of accuracy at runtime. Thus, we can make errors distributed more evenly. In contrast to other designs, our proposed design can maximize the performance gain since reconfigurable multipliers are able to operate two multiplications in parallel once the low accuracy mode is selected. Furthermore, we apply a simple rounding technique to approximate floating-point multipliers for additional improvement. Our simulation results reveal that our new method can reduce area by 70.98% when error tolerance margin of our target application is 5%, and when its error tolerance margin is 3%, our rounding enhanced simple adders-based approximate multiplier can save area by 65.9%, and our reconfigurable adder-based approximate multiplier with rounding can save the average delay and energy by 54.95% and 46.67% respectively compared to an exact multiplier.
Guidance for Cardiopulmonary Resuscitation of Children With Suspected or Confirmed COVID-19
Authors: Morgan Ryan W. , Atkins Dianne L. , Hsu Antony , Kamath-Rayne Beena D. , Aziz Khalid , Berg Robert A. , Bhanji Farhan , Chan Melissa , Cheng Adam , Chiotos Kathleen , de Caen Allan , Duff Jonathan P. , Fuchs Susan , Joyner Benny L. , Kleinman Monica , Lasa Javier J. , Lee Henry C. , Lehotzky Rebecca E. , Levy Arielle , McBride Mary E. , Meckler Garth , Nadkarni Vinay , Raymond Tia , Roberts Kathryn , Schexnayder Stephen M. , Sutton Robert M. , Terry Mark , Walsh Brian , Zelop Carolyn M. , Sasson Comilla , Topjian Alexis ,   on behalf of the American Heart Association Emergency Cardiovascular Committee and Get with the Guidelines-Resuscitation Pediatric Task Force in Collaboration with the American Academy of Pediatrics, American Association for Respiratory Care, and American Society of Anesthesiologists
Published: July 2022

This article aims to provide guidance to health care workers for the provision of basic and advanced life support to children and neonates with suspected or confirmed coronavirus disease 2019 (COVID-19). It aligns with the 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular care while providing strategies for reducing risk of transmission of severe acute respiratory syndrome coronavirus 2 to health care providers. Patients with suspected or confirmed COVID-19 and cardiac arrest should receive chest compressions and defibrillation, when indicated, as soon as possible. Because of the importance of ventilation during pediatric and neonatal resuscitation, oxygenation and ventilation should be prioritized. All CPR events should therefore be considered aerosol-generating procedures. Thus, personal protective equipment (PPE) appropriate for aerosol-generating procedures (including N95 respirators or an equivalent) should be donned before resuscitation, and high-efficiency particulate air filters should be used. Any personnel without appropriate PPE should be immediately excused by providers wearing appropriate PPE. Neonatal resuscitation guidance is unchanged from standard algorithms, except for specific attention to infection prevention and control. In summary, health care personnel should continue to reduce the risk of severe acute respiratory syndrome coronavirus 2 transmission through vaccination and use of appropriate PPE during pediatric resuscitations. Health care organizations should ensure the availability and appropriate use of PPE. Because delays or withheld CPR increases the risk to patients for poor clinical outcomes, children and neonates with suspected or confirmed COVID-19 should receive prompt, high-quality CPR in accordance with evidence-based guidelines.
Estado e autoritarismo na América Latina
Authors: Neves Fernando
Published: July 2022

Nas décadas de 1960 e 1970, a implementação de regimes autoritários na América Latina teve uma ampla repercussão nas pesquisas e debates em ciências sociais. As obras de Ruy Mauro Marini e Guillermo O’Donnell sobre o estado e o autoritarismo latino-americanos reúnem alguns desses impactos na produção do conhecimento social, em face de seu compromisso com o destino das sociedades em que se inseriam, embora a partir de princípios teóricos e perspectivas políticas distintos, heterogêneos e, por vezes, conflitantes. Essa contraposição teórica ganha relevância atualmente, dado o retorno de ideias e práticas autoritárias em nossas realidades sociais.
La feminización de los derechos migratorios: Mujeres activistas y una visión feminista para la protección de las personas migrantes de Centroamérica
Authors: Mendiola Daniel Matthew
Published: July 2022

El propósito de este artículo es analizar el pensamiento de varias mujeres en Centroamérica que lideran proyectos para disminuir la vulnerabilidad de las personas migrantes y fortalecer su bienestar. Este análisis se centra en una muestra de 17 entrevistas realizadas entre 2016 y 2017 por el Instituto Hemisférico de la Universidad de Nueva York. El argumento principal es que estas iniciativas están contribuyendo a crear una visión feminista para el futuro de las políticas migratorias. En particular, este pensamiento feminista representa una lógica fuerte para reivindicar los derechos de las personas migrantes en contra de la lógica neoliberal a raíz de las políticas migratorias actuales.
Gabino Gaínza: Jefe Político Superior de la Provincia de Guatemala
Authors: Cano Borrego Pedro Damián
Published: July 2022

El objetivo de este artículo es el estudio de la carrera militar de Gabino Gaínza y Fernández de Medrano, militar y político español nacido en Pamplona, Navarra, que se convirtió en el primer Jefe Político de la antigua Capitanía General de Guatemala independiente. Para su realización se ha estudiado la documentación de las fuentes disponibles sobre su vida y carrera militar en los principales archivos españoles, y muy especialmente en el Archivo General de Simancas, en el Archivo General de Indias y en el Archivo Histórico Nacional, así como el proceso que se le siguió en Valparaíso en 1815 por la firma del Tratado de Lircay y las principales referencias bibliográficas que tratan sobre su persona y época.
El puerto de Matina, entre la independencia y la formación del Estado nacional (región, recursos y población)
Authors: Payne Iglesias Elizeth
Published: July 2022

Se pretende estudiar las condiciones económicas del puerto de Matina a través del análisis de su composición espacial, las actividades productivas y el comercio local y regional. También se busca delimitar el hinterland de Matina y su área de impacto durante el periodo mencionado, para determinar el papel de este puerto como el centro de una región a lo interno del territorio costarricense, así como para entender su papel en el contexto de sus relaciones con la Mosquitia, Bocas del Toro y Jamaica. Este artículo también prueba que Matina y su entorno albergaban una población que, aunque bastante limitada y móvil, logró concretar un sitio estratégico en relación con los vecinos mosquitos, ingleses y colombianos, factor esencial que explica la consolidación del Estado de Costa Rica en la costa caribe del territorio.
La justa libertad de los pueblos. Las independencias en Centroamérica, Chiapas y Panamá. E. Payne y S. Herrera (Eds.). Sílex Ultramar. 2021
Authors: López Bernal Carlos Gregorio
Published: July 2022

Este libro, compilado por Elizeth Payne y Sajid Herrera, forma parte de la producción historiográfica sobre los procesos de independencia de Centroamérica en el contexto del bicentenario e incluye estudios sobre los actuales cinco países centroamericanos, pero incluye, además, un apartado sobre Chiapas y otro sobre Panamá. Está compuesto de una presentación y siete capítulos temáticos, y contiene mapas e ilustraciones.
El istmo de Panamá y su élite ante la independencia hispanoamericana de España en 1821
Authors: Chávez Jaramillo Jonathan J.
Published: July 2022

Este artículo parte de una investigación sobre los factores relevantes que sustentan por qué la independencia del istmo de Panamá de España se dio en 1821. Se analiza, en primera instancia, la función del istmo en el Imperio hispánico, luego, se estudia minuciosamente el proceso de decadencia imperial y el reordenamiento europeo de inicios del siglo XIX. Además, se reflexiona sobre la relación entre la era de las revoluciones globales y los movimientos independentistas americanos, a fin de ubicarnos en el contexto histórico adecuado. Posteriormente, se realiza una delimitación conceptual de las élites y sus características, para entender su papel en el istmo y la región, y se elabora una revisión de la historiografía reciente sobre Centroamérica y Panamá.
Puentes, no muros. Contribuciones para una política progresista en migraciones. Carlos Sandoval García (Ed.) (2020) y Centroamérica desgarrada. Demandas y expectativas de jóvenes residentes en colonias empobrecidas. Carlos Sandoval García (2020)
Authors: Rovira Mas Jorge
Published: July 2022

Las dos obras que son objeto de esta reseña crítica constituyen el fruto de un año de trabajo como Catedrático Humboldt 2017 de la UCR y el DAAD, con el apoyo también de la Oficina Regional para México, Centroamérica y Cuba de la Fundación Rosa Luxemburgo de Alemania. La primera de ellas, Puentes, no muros. Contribuciones para una política progresista en migraciones, devino en producto del coloquio “La politización de la migración. Desafíos para el pensamiento crítico y la política progresista”, que tuvo lugar en noviembre de ese año en la UCR. 

La segunda, Centroamérica desgarrada. Demandas y expectativas de jóvenes residentes en colonias empobrecidas, es el resultado de una cuidadosa investigación de campo sobre la situación en la que viven las personas jóvenes de los barrios populares de las principales ciudades de Centroamérica. Su elaboración escrita se benefició también de una licencia sabática que le otorgó al autor la Universidad de Costa Rica durante parte del año 2019.
Comentario dossier bicentenario centroamericano
Authors: Lindo-Fuentes Héctor
Published: July 2022

Las grandes conmemoraciones son una invitación para hacer un alto en el camino y reflexionar sobre el pasado. Esto es lo que está haciendo el Anuario de Estudios Centroamericanos (AECA) al producir un número especial para marcar el Bicentenario de la Independencia de Centroamérica.

Al leer el número del bicentenario del Anuario de Estudios Centroamericanos recuerdo las observaciones que hacían los salvadoreños hace 100 años. Veo el mismo tono de pesimismo y la misma actitud crítica. Encuentro una lectura de nuestra historia que trata de dilucidar las razones por las que nuestra vida política ha sido “seudo libre” como decía Peralta Lagos, por las que no pudimos perseverar en sistemas auténticamente democráticos. Veo comentarios directos e indirectos acerca del lastre de un pasado lleno de inestabilidad política y autoritarismo y del desafío de lidiar con las ambiciones imperiales estadounidenses.
Corpus-Based Translation Research on Legal, Technical and Corporate Texts
Authors: Camargo Diva Cardoso De
Published: July 2022

In an attempt to establish a possible ‘norm’ for the distribution of translation modalities in English → Portuguese translational relationship, a varied sample of three different text typologies (legal, technical, and corporate) with six representative texts of each typology was compared, producing a total of 9,000 lexical items. By applying Vinay & Darbelnet’s and Aubert’s models, it was possible to obtain a basic pattern of the distribution of the most used translation modalities as well as to verify certain variables, such as the correlation between a higher or lower fluctuation in the frequency of the modalities and different types of texts. From three different levels of data analysis, we observed a translation hierarchy in relation to the three most frequent categories: literal translation, transposition and modulation and also that legal texts on the one hand, and technical and corporate texts on the other, seemed to organise themselves into two major groups. We also obtained some elements which would enable us to sketch a correlation between the modalities of literal translation and technical and corporate texts, as well as a correlation between the modalities of modulation and transposition with modulation and legal texts.
17th-century views of polish towns in the swedish royal collections at drottningholm palace
Authors: Piramidowicz Dorota
Published: July 2022

The Royal Swedish Collection at Drottningholm palace includes, among various other such scenes, a series of battle paintings by Johan Philip Lemke (1631–1711). This painter, educated in the Netherlands and Italy, carried out two series of paintings to commemorate the wars of the two Swedish monarchs, Carl X Gustav and Carl XI. These enormous compositions painted on canvas were mounted into the walls of two rooms in the palace. One of these views, the series devoted to the victories of Carl X Gustav, comprises twelve pieces, eight of which depict panoramas of towns in the Polish–Lithuanian Commonwealth. Carried out in 1690–1705, these views were copied from the engravings of Eric Johnson Dahlbergh (1625–1703), as is explained in the inscriptions. Unfortunately, the poor condition of these pictures (the effect of 18th-century ‘conservation’ using sand...) rules out comprehensive analysis of what is depicted in them. It can be no more than suspected that Lemke’s Drottningholm paintings were of a high artistic quality. As is proven by his drawings currently housed in the National Museum in Stockholm, this artist was undoubtedly a magnificent painter. These days, more than anything else the paintings under examination represent an interesting attitude of the painter towards history and glorifying the ruler in question.
East asian art from western point of view: The case of bodhidharma, the founder of zen buddhism
Authors: Mecsi Beatrix
Published: July 2022

The impact of visual sources on the written tradition is exemplified here on the iconography of Bodhidharma. The pictorial tradition of the scene Bodhidharma Crossing the Sea is analyzed by the Author.
Gothic in the age of baroque on the ideological and formal reception of gothic art in the first half of the 18th century in Slovakia
Authors: Balážová Barbara
Published: July 2022

The Pietà statue found in the Holy Cross Chapel on the Calvary of Kremnica can be dated between 1729–1730. A letter of 1730 by the painter Johann Georg Rothenstein attest his collaboration in the construction of the Kremnica Calvary. The Kremnica Pietà belonmgs to a post–Gothic tradition.
News
Authors: Editorial Article
Published: July 2022

.
Behavioral, Pathomorphological, and Clinical Observations of a Young Harbor Porpoise (Phocoena phocoena) with Congenital Hemihydranencephaly
Authors: Kastelein Ronald A. , Kik Marja J. L. , Huijser Léonie A. E.
Published: July 2022

Internal anatomical disorders in marine mammals often only become apparent during necropsies. A case of hemihydranencephaly (HHAE) in a harbor porpoise (Phocoena phocoena) is described herein. HHAE is a rare, severe congenital brain disorder whereby one cerebral hemisphere is replaced by a sac filled with cerebrospinal fluid. The harbor porpoise was a formerly stranded and rehabilitated juvenile female, exhibiting behavior during her life in captivity that fell into two distinct modes. During her normal, “active” mode, she behaved like other harbor porpoises and performed well in training sessions. During her abnormal, “passive” mode, she listed onto her left side and floated with her right side at the water surface for several minutes at a time. At least her right eye would be closed, and she appeared to be in deep sleep. While floating at the surface and tilted over, she probably occasionally inhaled small amounts of water, resulting in recurring pneumonia. Ten months after stranding, at the age of ~24 months, the porpoise suddenly died. She was diagnosed with right-sided HHAE upon necropsy, which suggests that her passive-mode behavior was abnormal sleep. Cetaceans exhibit unihemispheric sleep so that they can maintain voluntary breathing, swimming, thermoregulation, body position, and vigilance. Possessing only one cerebral hemisphere, the porpoise lost the ability to sleep in this way. Following necropsy, the proximate cause of her death was probably an extensive lung edema followed by hypoxia, but the HHAE was assumed to be the ultimate cause. This case report shows that, despite the negative outcome, HHAE in harbor porpoises can be compatible with life and may not result in the cognitive or motor impairments that are seen in some human HHAE patients.
Knowledge and Attitudes towards Premarital Screening among Adolescents: A study in a University Setting
Authors: Dewi Annisa Triska Almanda , Susanti Ari Indra , Rinawan Fedri Ruluwedrata , Gondodiputro Sharon , Martini Neneng
Published: July 2022

Background: Premarital screening (PMS) is an action to prevent the occurrence of genetic and the transmission of infectious diseases. The screening has been recommended and promoted in Indonesia. This study aimed to assess the level of knowledge and attitudes towards premarital screening among teenagers in a university setting. Methods: This study used a cross-sectional design, including 310 adolescents aged 18–21 years at obtained through a non-random consecutive sampling at Universitas Padjadjaran. The data was collected from October 2020 until January 2021 using a close-ended questionnaire, assessing knowledge and attitude towards the PMS. The frequency knowledge level was grouped as good, moderate, and poor. The attitude level was categorized as positive and negative. Results: Most of the respondents (90.3%) had good knowledge of PMS. Respondents who had positive attitudes (79%) strong agreed that carrying out PMS was important, and 51% perceived that PMS needed to be a mandatory procedure before marriage. However, 59.6% had no idea how to deal if the result of the PMS was positive. Conclusion: In general, adolescents at Universitas Padjadjaran have good knowledge and a positive attitude towards PMS. However, comprehensive information about PMS is still needed, especially on decision points that must be taken after getting the test results.
CARCINOMA MAMÁRIO DUCTAL INVASOR: CORRELAÇÃO DA EXPRESSÃO IMUNOISTOQUÍMICA DE AXL E Β-CATENINA COM A AGRESSIVIDADE TUMORAL
Authors: Gennaro Lucas , Ribas Carmen Austrália Paredes Marcondes , Ramos Rafael Koerich , Ariede Bruno Luiz , Waaga-Gasser Ana Maria , Collaço Luiz Martins , Sigwalt Marcos Fabiano , Ribas Filho Jurandir Marcondes , Kubrusly Luiz Fernando
Published: July 2022

Introdução: O carcinoma ductal invasor corresponde ao tipo histológico mais comum da mama coexistindo com formas diferentes de evolução clínica, graduação histológica, expressão de determinados marcadores teciduais e perfis genômicos que procuram melhor entendimento da doença. Objetivos: Analisar a correlação dos marcadores β-catenina e AXL com a agressividade tumoral, tendo como referência a sobrevida global, progressão tumoral e fatores prognósticos histopatológicos. Métodos: Foi realizado estudo de 101 amostras de carcinoma mamário ductal invasor. Foram incluídas aquelas com diagnóstico do tipo ductal, submetidas inicialmente à biópsia ou tratamento cirúrgico definitivo. Incluiu-se para fins de controle 20 amostras de carcinoma intraductal, 35 de fibroadenoma mamário e 10 de tecido mamário sem qualquer alteração. Foram excluídos os submetidos à quimioterapia neoadjuvante, que não tivessem amostra tumoral prévia ao tratamento quimioterápico, que perderam o seguimento, e com dados incompletos. Resultados: Quando analisada a expressão da β-catenina, foi negativa. Quanto ao AXL foram observados diferentes graus de expressão sem significância estatística entre eles. Conclusão: Quando analisados adenocarcinoma mamário do tipo ductal invasor em TMA não houve correlação na expressão de ß-catenina e AXL quando comparados a sobrevida global, progressão tumoral e grau histológico.
Dapagliflozin Prevents Kidney Glycogen Accumulation and Improves Renal Proximal Tubule Cell Functions in a Mouse Model of Glycogen Storage Disease Type 1b
Authors: D’Acierno Mariavittoria , Resaz Roberta , Iervolino Anna , Nielsen Rikke , Sardella Donato , Siccardi Sabrina , Costanzo Vincenzo , D’Apolito Luciano , Suzumoto Yoko , Segalerba Daniela , Astigiano Simonetta , Perna Alessandra F. , Capasso Giovambattista , Eva Alessandra , Trepiccione Francesco
Published: July 2022

Significance Statement

Glucose homeostasis in proximal tubule cells requires an interplay between transport and metabolic activity. Using a mouse model of inducible G6PT suppression that mimics GSD1b disease, we demonstrate that hexokinase-1 activation and glycogen accumulation are the main causes of proximal tubule dysfunction. In addition, we provide proof of concept for the efficacy of dapagliflozin in preventing glycogen accumulation and, therefore, in restoring proximal tubule morphology and function, opening a new venue to repurpose this drug for treating patients with GSD1b.

Background

Mutations inSLC37A4, which encodes the intracellular glucose transporter G6PT, cause the rare glycogen storage disease type 1b (GSD1b). A long-term consequence of GSD1b is kidney failure, which requires KRT. The main protein markers of proximal tubule function, including NaPi2A, NHE3, SGLT2, GLUT2, and AQP1, are downregulated as part of the disease phenotype.

Methods

We utilized an inducible mouse model of GSD1b, TM-G6PT−/−, to show that glycogen accumulation plays a crucial role in altering proximal tubule morphology and function. To limit glucose entry into proximal tubule cells and thus to prevent glycogen accumulation, we administered an SGLT2-inhibitor, dapagliflozin, to TM-G6PT−/−mice.

Results

In proximal tubule cells, G6PT suppression stimulates the upregulation and activity of hexokinase-I, which increases availability of the reabsorbed glucose for intracellular metabolism. Dapagliflozin prevented glycogen accumulation and improved kidney morphology by promoting a metabolic switch from glycogen synthesis toward lysis and by restoring expression levels of the main proximal tubule functional markers.

Conclusion

We provide proof of concept for the efficacy of dapagliflozin in preserving kidney function in GSD1b mice. Our findings could represent the basis for repurposing this drug to treat patients with GSD1b.
Economic Resilience in the COVID-19 Pandemic
Authors: Highkin Emily , Van Leemput Eva
Published: July 2022

The global spread of COVID-19 virus in early 2020, and the measures taken to contain it pushed the global economy into a deep contraction. As illustrated in Figure 1, global GDP fell 10.5 percent below its pre-pandemic level in the second quarter of 2020.
[RETRACTED] Tiger Woods CBD Gummies & Shark Tank Reviews 2022 v1
Authors: not provided tigerwoodsieshartank
Published: July 2022

[RETRACTED]

Tiger Woods CBD Gummies & Shark Tank Reviews 2022
[RETRACTED] Beliv Blood Sugar Support Real Customers Real Life Changing Results v1
Authors: not provided belivblood
Published: July 2022

[RETRACTED]

Beliv Blood Sugar is a cutting-edge diabetes treatment that eliminates the root cause of type 2 diabetes. Individuals can live a healthy life with normal blood sugar levels and improved glucose metabolism if they eat the correct amount of carbohydrates.
[RETRACTED] Beliv Blood Sugar Support:-Controlling Blood Pressure And Blood Sugar! v1
Authors: not provided belivbloodsugar
Published: July 2022

[RETRACTED]

Blood sugar concerns affect customers worldwide. Diabetes affects millions of individuals, but elevated blood sugar may also lead to additional complications. The most prevalent cause of elevated blood sugar in consumers is type 2 diabetes. However, heart disease, hypertension, and obesity are all potential causes.
[RETRACTED] Ikaria Lean Belly Juice New Zealand v1
Authors: not provided Shanndoughty
Published: July 2022

[RETRACTED]

Ikaria Lean Belly Juice New Zealand
[RETRACTED] https://wintersupplement.com/vissentials-max-keto-reviews/ v1
Authors: not provided keto-x-reviews
Published: July 2022

[RETRACTED]

https://wintersupplement.com/vissentials-max-keto-reviews/
Establishing an Appeal Mechanism for Investor-State Dispute Settlement: Challenges, Feasibility, and Options
Authors: Zhang Xi , Ab Rahman Rozanah
Published: July 2022

There is a growing international consensus stating investor-state dispute settlement mechanism (ISDS), with international investment arbitration as the main means of dispute settlement, needs to be reformed, but the reform proposals have not yet been finalised. Among the many options, the option of establishing an appeal mechanism has generated extensive discussion. The permanent, independent and corrective nature of the appeals mechanism helps to address the lack of independence and impartiality of arbitrators under the ISDS mechanism, the inconsistency of arbitral awards, and the lack of control mechanisms. It also has benefit of improving the accuracy of awards. Under the current system of international investment treaties, establishing a multilateral appeal mechanism presents many challenges. However, the Mauritius Convention on Transparency, which uses multilateral instruments to amend bilateral treaties, provides evidence that establishing a multilateral appeal mechanism is feasible.
Police Responsiveness into Behavioural Health Crisis
Authors: Ch'ng Xin Hwa
Published: July 2022

Law enforcement, the representative image of the official power among the public and community, is important to maintain its integrity and legality when executing its power enshrined by the laws. Yet, the debate regarding the abuse of the police power had gained tremendous mistrust within the community, flagging the insensitiveness of the law enforcement in handling suspects who are vulnerable upon arrest. This could be detrimental to build up the integrity and the accountability of the police in the eyes of the public. The purpose of this article seeks to propose a proactive alternative that could be utilized to manage the incidence of behavioural health crisis of arrested persons more effectively and efficiently. In achieving this objective, the criminal procedure in Malaysia is discussed. This is followed by a doctrinal analysis on the manner of the arrest required for the responsiveness into behavioural health crisis. It is observed that the outreach of procedural justice into the suspects who are mentally vulnerable is not in the common address within our existing criminal procedure. A conclusion could be outlined that a proactive alternative is arguably crucial to improve the existing circumstances. The intervention is expected to be a novel approach to improve the literacy of the law enforcement with behavioural health crisis which includes the criminal procedural justice to be addressed effectively and efficiently.
The Golden Liquid and Criminal Opportunity
Authors: Abdul Samad Azlinda , Abdul Ghani Abdul Samad
Published: July 2022

The situation of the COVID-19 pandemic resulted in the whole world scrambling to find a vaccine that could help contain the pandemic that is raging. This is because COVID-19 vaccines are seen as the best possible solution for containing the virus in the current situation. However, once the vaccines for COVID-19 received approval for use, the high demand for this new ‘liquid gold’ has resulted in some unscrupulous parties taking advantage of the situation by committing organised crime with the intention of profiting from the vaccines. As a result, there are now threats of substandard and counterfeit vaccines in the supply chain. The high demand for the vaccines globally and the limited supplies have further spurred this criminal intent. Additionally, the desperation among the global population to get a hold of the COVID-19 vaccines has seen the online platform being used as the medium for perpetrating these criminal activities. The allocation and distribution of the vaccines are also unprecedented because of the global scale of the pandemic and many countries are rushing to get their population vaccinated in the hope of curtailing the virus. Thus, the risk of corruption may take place at any stage of the allocation and distribution process, and eventually, this could pose serious threats to public health goals. For this reason, these threats must be identified, mitigated and handled carefully. Co-operation, communication and networking among the relevant bodies and the pharmaceutical industry are therefore vital. Additionally, law enforcement agencies need to be prepared and ready for any unanticipated circumstance. Governments must be transparent and accountable, and governance must be put in place. Awareness among all parties involved is indeed crucial but most importantly, the public must be educated on the risk of purchasing COVID-19 vaccines online.
The effect of Basic Oxygen Furnace, Blast Furnace, and Kanbara Reactor Slag as Reinforcement to Cement Based Mortar
Authors:   Department of Metallurgical Engineering, Institut Teknologi Sains Bandung, Harmaji Andrie , Hardiansyah Andri ,   Research Center for Physics, National Research and Innovation Agency (BRIN), Widianingsih Neneng Annisa ,   Department of Metallurgical Engineering, Institut Teknologi Sains Bandung, Jannah Rodulotum Minriyadlil ,   Department of Metallurgical Engineering, Institut Teknologi Sains Bandung, Soepriyanto Syoni ,   Department of Metallurgical Engineering, Institut Teknologi Bandung
Published: July 2022

Slag is a waste from steelmaking industries that was released into the environment. Slag was used as reinforced material in mortar. Different types of slag, including Air Cooled Slag (ACS), Granulated Blast Furnace Slag (GBFS), Basic Oxygen Furnace Slag (BOFS), and Kanbara Reactor Slag (KRS), were used as a reinforcing material in this study. The composition of slag in the mixture on mortar was 10%, 20%, 30%, 40%, and 50%. The sample was made with a water-cement ratio (w/c) of 0.35, with the ratio of sand and cement being 1:1.5, respectively. Treatment of mortar sample at ambient temperature was applied. The mortar samples were left to cure until 3, 7, and 28 days, which performed a compression test. The results show that adding slag to the mortar enhanced the compressive strength of the pristine mortar. The highest strength was obtained by adding 10% slag at 28 days. The compressive strength of GBFS, BOFS, KRS, and ACS was 23.76 MPa, 23.28 MPa, 19.68 MPa and 17.48 MPa, respectively. Based on the XRD result, it was discovered that the mixture has more Calcium Silicate Hydrate Peak than Pristine mortar.
Campesinado en páramos: compatibilidad ambiental constitucional
Authors: Mesa Villamil Delma Camila , Mesa Cuadros Gregorio
Published: July 2022

Los seres humanos usamos de manera diferente la naturaleza, y esto define las prácticas culturales en ecosistemas y tiempos históricos diversos. Las comunidades campesinas vienen habitando los páramos de Colombia desde hace más de 150 años. Históricamente, estas comunidades han sido acusadas de ser depredadoras y contaminadoras, pero recientemente han identificado prácticas sostenibles destinadas a la satisfacción de sus necesidades básicas que usan un mínimo de los elementos de su ecosistema. Esto contrasta con las prácticas extractivistas y de infraestructura para el turismo que dañan estos frágiles ecosistemas. La protección de los derechos del campesinado puede contribuir significativamente a la protección de los páramos; de ahí la idea de que existe una compatibilidad entre la presencia campesina y la conservación de ecosistemas esenciales para la vida.
Modelling framework of the Tandem Supply Chain Efficiency and Sustainable Financial Performance in the Automotive Industry
Authors: Burta Simona , Nicolescu Ana-Cristina , Vătavu Sorana , Bozga Emilia , Lobonț Oana-Ramona
Published: July 2022

The research examines the causal relationship between supply chain efficiency and sustainable financial performance based on the evidence from the literature dealing with a transition from financial decision-making based on the financial outcome, including financial rationale in supply chain design, operations, and management. The case study has included 100 companies selected from the automotive production sector over ten years, from 2010 to 2019. Methodologically, the study includes statistically fixed and random effects models, considering within the model parameters as dependent variables asset and efficiency-based ratios and as independent variables financial performance ratios related to returns on assets, equity, capital expenses, and sales. The selection of the fixed or random- effects model is accomplished by performing the Hausman test. The results of panel analysis indicate a causal relationship for the proposed models, highlighting the importance of efficiency ratios such as Fixed Assets Turnover Ratio, Total Assets Turnover Ratio, and Fixed Assets Turnover. From practitioners` perspective, the models` construction and the paper’s results gain insight into strategic supply chain areas that can be prioritised for increased efficiency and corporate competitiveness, promoting sustainable financial performance through asset structure, asset efficiency, and inventory management.
Bandung Cooperation with Braunschweig (Germany) in Realizing Smart City
Authors: BJ Tina Rosaliana  , Dyah Estu Kurniawati  , Deva Joshua Kamisi
Published: July 2022

The Bandung City has carried out various international cooperations to obtain investments in the long or short term, support for infrastructure development, youth exchanges, cooperation in culture, and receipt of fees and grant funds. One of the various cooperations is the efforts of Bandung in paradiplomacy through the sister city concept. This study is necessary because Bandung and Braunschweig have carried out the Sister City Program from 1960 to 2021. This research is a descriptive study with a qualitative approach, examining why Bandung maintains cooperation with Braunschweig (Germany), running for more than 40 years. This article employed data collected from journals, news in the mass media, and information from the official websites of related parties as supporting references. In answering the research question, the author utilized the concepts of smart city and sister city. This study discovered that Bandung maintained its cooperation with Braunschweig due to its interest in building a smart city.
Peran dan Kedudukan Dewan Gelar, Tanda Jasa Dan Tanda Kehormatan Dalam Sistem Ketatanegaraan Di Indonesia
Authors: Nurjannah Nurjannah
Published: July 2022

The aim of this study is to determine the role and position of the Dewan Gelar, Tanda Jasa dan Tanda Kehormatan (Dewan GTK) in the Administration System in Indonesia. The research method used is empirical normative research using a statutory approach. The results of the study found that Dewan GTK is a supporting institution or state auxiliary bodies or auxiliary institutions for executive power in the system of state administration in Indonesia. According to the theory of State Auxiliary Bodies (SAB), Dewan GTK includes Executive-Auxiliary, namely SAB that is included in the executive realm in general at the auxiliary level. In this category there are two different types of SAB functions which are to coordinate and to provide policy suggestions / recommendations to the President which based on its formation consists of two, namely, formed by the President and the second formed to represent certain groups to provide advice and input to the government. Dewan GTK is included as Auxiliary-Advisory, namely SAB which provides advice and considerations to the President.