bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of cholelithiasis and complications in patients with sickle cell anemia and beta-thalassemia in Saudi Arabian population
Authors: Badeeb Arwa , Almotadaris Saja , Alharbi Roaa , Alnemari Renad , Alsharef Raghad , Alghazzawi Fayafi , El-Diasty Mohamed
Published: November 2022

Background: Saudi Arabia falls in the highly prevalent zone of sickle cell anemia (SCA) and thalassemia. This chronic hemolysis causes the development of bilirubin cholelithiasis, which can be symptomatic, resulting in cholecystitis, choledocholithiasis, ascending cholangitis, or gallstone pancreatitis. The study aims to determine the prevalence of cholelithiasis and associated gallstone complications among patients with sickle cell disease and thalassemia presenting to King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Methods: This retrospective study included patients diagnosed with SCA and thalassemia who had at least an abdominal ultrasound, Computed Tomography, or Magnetic Resonance Imaging. Social, epidemiological, and clinical characteristics, such as gender, age, nationality, Body Mass Index, medical and surgical history, and the presence of other hemoglobinopathies, were collected. In addition, the prevalence of gallstones was assessed and compared between both groups. The association with patients' characteristics was also evaluated.
Results: Among the total of 542 patients included, 338 (62.3%) had SCA, of which 184 (54.4%) developed gallstones. Further more 204 (37.5%) had thalassemia, of which 51 (25%) developed gallstones. SCA cases had a higher prevalence of gallstones, sludge, cholecystitis, cholangitis, choledocholithiasis, pancreatitis, and cholecystectomy. The age of gallstone diagnosis is significantly lower in SCA compared with beta-thalassemia (18 ± 9.7 and 25.7 ± 14.2 years, respectively) (p < 0.001).
Conclusion: Gallstone disease was more prevalent and diagnosed at a younger age in SCA than in thalassemia patients. However, the incidence of complications and cholecystectomy was similar between the two groups.
Yin and Yang Cover the Universe as a Whole
Authors:   Chinese Academy Of Traditional Chinese Medicine, Cao Hongxin
Published: November 2022

All things, phenomena and laws in the universe can be revealed and explained by yin-yang
Encryption Symmetric secret Key in Wireless Sensor Network Using AES Algorithm
Authors: Hussein Sahar Najah , Obaid Ali Hamzah , Jabbar Ali
Published: November 2022

Wireless sensor network (WSN) security is an important component for protecting data from an attacker. For improving security, cryptography technologies are divided into two kinds: symmetric and asymmetric. Therefore, the implementation of protocols for generating a secret key takes a long time in comparison to the sensor’s limitations, which  decrease network throughput because they are based on an asymmetric method. The asymmetric algorithms are complex and decrease network throughput. In this paper, an encryption symmetric secret key in wireless sensor networks (WSN) is proposed. In this work, 24 experiments are proposed, which are encryption using the AES algorithm in the cases of 1 key, 10 keys, 25 keys, and 50 keys. In each experiment, two chains are combined by using a hash function (SHA-2) to produce secret keys. The Network Simulator Version 2 (NS2) was used to assess the network throughput for the generated key. The randomness of the suggested LWM method has been tested by using the Diehard statistical test and the Entropy test. The results of the tests show that the encryption secret keys have a high level of data randomness.
Factors affecting intention to continue volunteering with job satisfaction as mediation
Authors: Aseanty Deasy , Wahyu Gunawan Andreas , Julieta Giane
Published: November 2022

This study discussed whether there is a positive influence between Volunteer Management and Work Environment on Intention To Continue Volunteering mediated by Job Satisfaction of Central Jakarta Disaster Siaga Taruna (TAGANA) volunteers.
This study aims to analyze the variables namely Volunteer Management, Work Environment, Intention To Continue Volunteering and Job Satisfaction and aims to analyze the positive influence between Volunteer Management on Job Satisfaction, To analyze the positive influence between Work Environment on Job Satisfaction, To perform analysis of the positive influence between Job Satisfaction on Intention To Continue Volunteering, To analyze the positive influence between Volunteer Management on Intention To Continue Volunteering mediated by Job Satisfaction, To analyze the positive influence between Work Environment on Intention To Continue Volunteering. The research method is descriptive quantitative with the aim of testing hypotheses, the data used are cross sectional, the unit of analysis used is the individual and the background of this research is no contrived setting. This research is related to the field of Human Resource Management, in particular to see the relationship between the Job Satisfaction variable with the concept of Green Society and Green Human Resource Management.
The results of this study indicate that the Volunteer Management and Work Environment variables have a positive effect on Job Satisfaction, the Job Satisfaction variable has a positive effect on Intention To Continue Volunteering, Volunteer Management and Work Environment have a positive effect on Intention To Continue Volunteering mediated by Job Satisfaction. The limitations of this research are that it is only conducted in one organization, namely Central Jakarta Disaster Preparedness Youth (TAGANA), the research variables used are only Volunteer Management, Work Environment, Intention To Continue Volunteering and Job Satisfaction and the research respondents are volunteers in the Disaster Preparedness Team. (TAGANA) Central Jakarta.
PERCEPTION IN FORENSIC ACCOUNTING EDUCATION IN MALAYSIA: A COMPARISON BETWEEN ACCOUNTING UNDERGRADUATES AND PRACTITIONERS
Authors: Mohamad Yusof Norzalina , Abdul Kadir Dzarfan , Naimi Mohamad Nor Mohamad
Published: November 2022

This study intends to gain insights on students' and practitioners' perception on demand for and interest in forensic accounting practices; relevance of forensic accounting education; important learning mechanisms; and topical content of forensic accounting education. A seven-part questionnaire was distributed to UUM students enrolled in Forensic Accounting course; and to practitioners, which include auditors and CFE members. The results reveal that both students and practitioners view highly on the benefits of forensic accounting education and expect to see an increase in future demand and interest in three areas of forensic accounting. However, practitioners feel that the present accounting curriculum is not sufficiently responsive to society's demand for forensic accounting education. Improvements in the curriculum content of forensic accounting subject are also needed. Topics such as cyber and computer fraud need to be given more attention in the classroom. The results of the study could be used by education providers in designing forensic accounting syllabus. JEL Classification : Keywords: Forensic Accounting, Accounting Education, Malaysia
PENGARUH ORIENTASI PASAR TERHADAP KINERJA BISNIS: SUATU STUDI PADA INDUSTRI RITEL DENGAN MENGGUNAKAN SKALA MARKET ORIENTATION (MARKOR)
Authors: Rahardjo Purwanto , Sirait Justine
Published: November 2022

The background of this research "conventional marketing wisdom holds that a market orientation provides a company with a better understanding of its customers, competitors and environment, which subsequently leads to superior business performance. While researchers have explored the relationship between market orientation and business performance in different organizations, such studies in retailers industry are scarce."The objective of this research: "Is there an influence from the market orientation towards business performance of retailers industry?". This research is attempt to test the links among three dimensions of market orientation (intelligence generation, intelligence dissemination and responsiveness) and also the link between market orientation and business performance."Data for this study were collected through personal interviews; and Kohli, Jaworski and Kumar's market orientation scale was used to specify the dimensions of a market-oriented organization. These questions were structured in a Likert Scale model. Because of the size of the sample and number of variables; this research used the Structural Equation Modelling (SEM) analysis."The result of this research conclude that Kohli, Jaworski, and Kumar's market orientation scale provides a good measure of market orientation in this setting. Also the results of analysis indicated a significant link between market orientation and retailers industry performance.Keywords : Market orientation, Intelligence generation, Intelligence dissemination, Responsiveness, Business performance
Ochrona konsumentów przed nieuczciwymi praktykami rynkowymi na rynku finansowym
Authors: Horosz Piotr
Published: November 2022

Artykuł koncentruje się na problematyce ochrony konsumentów przed nieuczciwymi praktykami rynkowymi w sektorze finansowym, omawiając pod tym kątem regulacje prawne zawarte w przepisach ustawy o przeciwdziałaniu nieuczciwym praktykom rynkowym.

Omawiając praktyki rynkowe godzące w interes konsumentów, zwłaszcza praktyki wprowadzające w błąd oraz agresywne praktyki rynkowe autor wskazuje na generalny zakaz stosowania takich praktyk, obowiązujący również w przypadku konsumentów korzystających z usług finansowych. Jednocześnie autor podkreśla, że ochrona konsumentów przed nieuczciwymi praktykami rynkowym na rynku finansowym jest wzmocniona w porównaniu z ochroną konsumentów na innych rynkach. Wynika to zwłaszcza z funkcjonowania na rynku finansowym szczególnych organów – zwłaszcza Komisji Nadzoru Finansowego i Rzecznika Finansowego, które w ramach swoich ogólnych kompetencji, mogą również podejmować działania służące ochronie konsumentów usług finansowych przed nieuczciwymi praktykami rynkowymi.
Rozwój systemów motywacyjnych w spółkach kapitałowych
Authors: Żochowski Wiktor Marek
Published: November 2022

Opracowanie modelu przyznawania udziałów może być sposobem na zatrzymanie w spółce doświadczonej kadry menedżerskiej oraz zasłużonych pracowników. Wzmocnienie więzi kluczowego pracownika ze spółką poprzez zastosowanie różnych rozwiązań przeważnie stanowi bodziec motywujący i zachęcający go do większego zaangażowania w sprawy spółki.
Celem pracy jest, na tle przedstawionych systemów motywacyjnych, rozważenie słuszności wprowadzania opcji menedżerskich do umowy spółki jak i nakreślenie postulatów de lege ferenda w zakresie standardów wprowadzania systemów motywacyjnych do systemów osób prawnych.
Developing Language Skills for 4-5 Years Old Children at RA Muslimat NU 1 Tulus Rejo Kec. Pekalongan Through the Development of Ice Cream Stick Media
Authors: Janah Annisa Nur
Published: November 2022

sticks are learning media that can stimulate the teaching and learning process. The use of ice cream stick media at RA Muslimat NU 1 Tulus Rejo Kec. Pekalongan has not been used in learning, besides that the media material for ice cream sticks is very easy to get and cheap. The language ability of children aged 4-5 years is the lowest level of achievement compared to other abilities. development of ice cream stick media at RA Muslimat NU 1 Tulus Rejo with the following steps: 1) Ice cream sticks were developed into letter sticks. One side is written with letters, one side is also written with letters, 2) At first the child reads the letters on one side, 3) If correct, the child may read the letters on the other side. 4) If the child wants to learn to read, the game is reversed, the child reads one side of the letter first and then opens the side with the letter on the other side, 5) If the child answers correctly, he/she is given a picture of a smile, and if he/she answers incorrectly, he/she is given a picture of crying. The use of ice cream stick media for children aged 4-5 years at RA Muslimat NU 1 Tulus Rejo can improve children's language skills.
Development of Bekel Ball Game to Improve Cognitiveness Children aged 5-6 Years in Kec. Way Seputih Central Lampung
Authors: Rahayu Tri , Putra Windisyah
Published: November 2022

Educational games are useful for improving language skills, cognitive skills, and getting along with the environment. Cognitive is the ability to acquire and use knowledge in order to solve problems and adapt to the environment. The researcher chose the cognitive aspect because of this ability in RA Muslimat NU 10 Sri Budaya Kec. Way Seputih, Central Lampung is still relatively undeveloped. The purpose of this research is the development of bekel ball game at RA Muslimat NU 10 Sri Budaya Kec. Way as white as Central Lampung. Types of research and development (research and development). The development procedure according to the 4D model consists of four stages, namely Define, Design, Develop, Disseminate. Based on the results of the study, it can be concluded that the development of bekel ball game media at RA Muslimat NU 10 Sri Budaya Kec. Way Seputih Central Lampung with the following steps: 1) The teacher prepares the bekel ball game media. 2) The teacher explains the rules of the game using bekel ball game media. 3) The teacher gives examples of the steps of the Bekel ball game. 4) The child is asked to roll the bekel ball. 5) The child will get a prize in the form of one star if he answers correctly, while if the child answers incorrectly, the child will get a punishment in the form of reading a short letter. 6) The child is asked to name the number symbol on the bekel ball falling hole. 7) Children are asked to count the number of numbers in each hole that the bekel ball falls. 8) Children are asked to match the number with the number symbol in each hole the bekel ball falls. 9) Each hole consists of a picture and the name of the picture. 10) The child is asked to explain each picture on the bekel ball falling hole. The Effectiveness of Using Bekel Ball Game Media to Improve Cognitive Aspects of Children aged 5-6 years at RA Muslimat NU 10 Sri Budaya Kec. Way Seputih Central Lampung which is very effective.
Marketing Strategy Management for Early Childhood Education RA Al Wardah North Sumatra
Authors: Yuning Eka Rahma Wati
Published: November 2022

Marketing management can be used as a mechanism for explaining and rationalizing a program's offerings with various advantages, both in terms of inputs (inputs), processes, products (outcomes), outputs (outputs), and graduates (effects). In addition, promotion can also be used to convey public accountability regarding the educational process and results that have been implemented and developed by the educational institution concerned. The formulation of this research is how the education marketing management process in RA Al Wardah North Sumatra, what are the targets to be achieved by RA Al Wardah North Sumatra with the implementation of marketing management, what is faced by RA Al Wardah North Sumatra in the performance of marketing management. The research was conducted in RA Al Wardah, North Sumatra, and the data source for this study was the principal. This study uses qualitative research methods. Observation, interviews, and documentation do data collection. Data analysis is done through data reduction, data presentation, and conclusion. Based on the study results, it can be concluded that marketing management at RA Al Wardah, North Sumatra is running very well and following the times. The marketing strategy by RA Al Wardah North Sumatra is to continuously improve the quality of educational services, has the characteristic of educating children to be pious and independent, holding various extracurricular activities outside school hours, and holding multiple competitions.
Improving Early Children's Language Capabilities through Interactive Compact Disk Media
Authors: Ansorida
Published: November 2022

Language skills are essential skills to be developed from an early age. That's because language is an important means in human life to communicate. With language, humans can issue ideas and opinions to establish communication with other humans. Thus, language skills should have been improved since early childhood. In line with the development of science and technology, various kinds of learning media can be found that can be used to develop students' abilities, one of which is interactive compact disk media. The research was conducted at Raudhatul Athfal Al-Hikmah Kedaton Bandar Lampung. This research is a Classroom Action Research with a qualitative descriptive type. The data collection technique that the researcher uses is the observation method as the primary method, the documentation method as support in research, and the interview method to determine the extent of the teacher's response to the use of interactive compact disk media in improving children's language skills. The results of this study that interactive compact disk media can improve children's language skills in Raudhatul Athfal Al-Hikmah Kedaton Bandar Lampung with very satisfying results. This can be seen from the development of students in the pre-cycle research it is known that students who reach the assessment standard develop according to expectations. There are only 3 children out of all 15 students. Then in the first cycle, the number of children who had the language skills as expected increased to 9 children, and in the second cycle, it rose again to 12 students or 80% of the students had reached the assessment standards that had been set.
KUALITAS PELAYANAN PARKIR BERLANGGANAN DI KOTA PASURUAN
Authors: Setiawan Ardian Bagus , Widiyarta Agus
Published: November 2022

Retribution is a regional levy as payment for services or the granting of certain permits specifically provided or granted by the Regional Government for the benefit of individuals or entities. In a retribution there are services provided by the government. The services provided by the government or often called public services are not all running well. This article aims to explain the quality of subscription parking services in Pasuruan City from the aspect of public services. This research is important to do because there are many complaints from the public as service users regarding the services provided by the subscription parking operator. This study will focus on analyzing respondents' responses to the dimensions of public services which are divided into responsiveness, responsibility, and accountability. The method used in this research is a quantitative approach with descriptive research type survey research category. Respondents in this study amounted to 100 people who are users of subscription parking services in Pasuruan City. In this study using simple random sampling as a sampling technique. The results show that the quality of subscription parking services in Pasuruan City gets a score of 74.6% or is included in the good category.
Online Learning Infrastructure: Does it Strengthen the Effect of Service Quality on Student Satisfaction?
Authors: Marlena Novi , Renny Dwijayanti  , Finisica Dwijayati Patrikha  , Saino
Published: November 2022

One of the main obstacles to online learning is learning infrastructure and the availability of internet facilities, i.e., internet quotas. Universitas Negeri Surabaya (UNESA) students regularly receive internet quota assistance from the Minister of Education and Culture and Universitas Negeri Surabaya. Therefore, it is expected that the online learning process will run well. The study aimed to determine 1) the impact of the online learning service quality on student satisfaction and 2) the moderation effect of Infrastructure to strengthen the effect of service quality on student satisfaction in online learning. The subjects of this study were students of the UNESA, Indonesia, with 250 students as research samples. Data collection was done by distributing online questionnaires using google forms. The data analysis technique used moderated regression analysis. The results proven that 1) the online learning service quality affects student satisfaction, 2) infrastructure as the moderator variable not proven as a moderator model, but infrastructure has a direct influence on student satisfaction in online learning.
Keywords: Online Learning Infrastructure, Students Satisfaction, Learning Quality
Arabic Learning Design Based on 21st Century Skills during the Covid-19 Pandemic in Indonesia
Authors: Susanto  , Apri Wardana Ritonga  , Ayu Desrani  , Yohan Rubiyantoro
Published: November 2022

The Covid-19 pandemic that hit Indonesia changed learning patterns from offline to online using technology as media. Hence, Arabic language learning must be well designed but still contains elements of 21st century life skills. This study aims to explore the design of 21st century skills-based Arabic learning which was held during the Covid-19 pandemic at Thursina International Islamic Boarding School Malang, Indonesia. This research adopts a qualitative approach with a case study method. Data were collected through observation, interviews, and document studies. The data collected were analyzed using the theory of Miles and Huberman, namely reducing, presenting, and verifying. Furthermore, the data is validated using data triangulation and data sources. This research shows that the implementation of 21st century skills can be done online during the Covid-19 pandemic; achievement indicators refer to the content of elements in 21st century skills known as 4C (critical thinking, communication, collaboration, and creativity & inovation) terminology; while the challenges of implementing 21st century skills stem from the skills of teachers in operating technology when presenting subject matter to students. The findings of this study describe that 21st century skills encourage students to become globally competitive human resources. The researcher recommends the next research to test the effectiveness of internalizing 21st century skills with online learning models.
Keywords:  Arabic Learning Design, Learning Design, Learning Arabic
Development of Stopmotion Video Animation Media in Qawa'Id Learning for Class XI Madrasah 'Aliyah Students | Pengembangan Media Animasi Stopmotion Video dalam Pembelajaran Qawa’Id pada Siswa Kelas XI Madrasah ‘Aliyah
Authors: Ariska Djian , Indrawati Ninik , Zainuddin Ammar
Published: November 2022

This research is motivated by various problems and obstacles in the qawā'id learning this is also because teachers do not innovate in using learning media in delivering qawā'id. With this, the researcher developed audiovisual media in the form of stopmotion video animation for learning Arabic qawā'id, with the stopmotion video animation media containing moving writing along with explanations and examples of qawā'id material which was able to make students get a real picture of the application of Arabic rules.The type of research used Research and Development (R&D) using a modified Borg and Gall development model.  From the results of the analysis, the average assessment of media experts and stopmotion animation learning media materials is 70.5% and is declared "valid" and suitable for use as qawā'id learning media.
Musical Rhythm in Poetry ‘Al-Jaddu Yudni Kulla Amr Syasi’in’ by Imam Syafi’i (Critical Analysis of ‘Arudh and Qowafi)|Irama Musikalitas pada Puisi ‘Al-Jaddu Yudni Kulla Amr Syasi’in’ Karya Imam Syafi’i (Analisis Kritik Sastra Arudh dan Qowafi)
Authors: Latif Abdul , Jannah Faidatul
Published: November 2022

Imam Syafi'i is well known as a jurist, but he also has works in the field of literature. His literary works in the form of poetry are composed using the rules of arudh and qawafi. In the rules of Arabic poetry, the rhythm of the musicality of a poem is determined by the consistency of using the rules of Arudh and Qawafi, therefore the purpose of this study is to find the rhythm of musicality and analyze the shortcomings and advantages of the poetry of the Shafi'i imam with a descriptive qualitative method. The results of this study found two rhythms of musicality that exist in this poem, namely using the types of bahr Kamil and Rojaz. His qafiyah takes the form of a part of the word from the final fragment of the verse of the poem. This poem also has several advantages, namely, the first stanza to the end has the same wazan taf'ilah and the qawafi reads the letter ق and is in the form of a part of the word, and in the second stanza, when viewed from the type of bahr Rojaz then the wazan taf'ilah is free from zihaf. While the drawback is that in the first stanza to the end there is a zihaf al-idhmar that enters it, in the qawafinya where the fourth and fifth stanzas of the qafiyah there is zihaf al-idhmar, and in the third stanza the final sound of the stanza is different from the other stanzas, with fathah tone. This research shows that although better known as a jurist, Imam Shafi'I also has literary works that have a high musical rhythm value.
Evaluating quality of life and satisfaction with pharmaceutical care services among patients with type II diabetes mellitus receiving care in a resource-limited setting
Authors: Eshiet Unyime Israel , Ante Blessing , Uwak Abasiodiong
Published: November 2022

Objectives:

Quality of life assessment is considered an important measure of outcome in long-term illness and management. Patient satisfaction surveys are essential in obtaining a comprehensive understanding of the patient’s needs and their opinion of the service received. The purpose of this study was to determine the health-related quality of life (HRQOL) and satisfaction with pharmaceutical care services among patients with type II diabetes mellitus (DM) receiving care in Nigeria.

Materials and Methods:

A cross-sectional prospective study was conducted among 120 patients with type II DM receiving treatment at General Hospital Ikot Ekpene in Akwa Ibom state, Nigeria. Patients who met the eligibility criteria and attended clinic appointments at the medical outpatient clinic as well as those admitted into the medical wards of the hospital during the period of the study were recruited. Data on the extent of patients’ satisfaction with pharmaceutical care as well as their quality of life in diabetes were obtained using the patient satisfaction with pharmaceutical care questionnaire, and the patient quality of life based on diabetes related complaints questionnaire. The duration of the study was 7 months. Data obtained were analyzed using the Statistical Program and Service Solutions version 25.0 computer package with statistical significance set at P < 0.05.

Results:

The quality of life of the patients based on diabetes-related complaints was poor. Fatigue was the most frequently reported complaint (n = 116; 96.6%), followed by polyuria (n = 106; 88.33%). The overall mean scores of patient satisfaction with pharmacists’ friendly explanation and management of therapy were 4.03 (±0.52) and 3.53 (±0.44), respectively. There was a statistically significant relationship between patients’ satisfaction with pharmacists’ friendly explanations and patient complaints of weight changes (r = 0.219; P < 0.05), decreased energy levels (r = 0.205; P < 0.05), and numbness (r = 0.270; P < 0.01). Furthermore, there was a statistically significant relationship between patients’ satisfaction with pharmacists’ therapy management and patients’ complaint of fatigue (r = 0.187; P < 0.05), numbness (r = 0.189; P = 0.05), and blurred vision (r = 0.204; P < 0.05).

Conclusion:

The HRQOL of the patients was poor as the majority of the patients had diabetes-related complaints. Patients’ satisfaction with the pharmaceutical care services offered was good. Periodic evaluation of the quality of life and satisfaction with health-care services among patients with DM is recommended.
Covid-19-associated rhino-orbito-cerebral mucormycosis (CAROM) in Delhi: Demographics and risk factors in a single-centre consecutive cohort of 200 inpatients
Authors: SINGH ANUP , SIKKA KAPIL , GOEL GAURAV , KANODIA ANUPAM , CHANDRAN ASWIN , KONKIMALLA ABHILASH , PANDA SMRITI , GARG ROHIT K. , XESS IMMACULATA , TANDON NIKHIL , THAKAR ALOK
Published: November 2022

Background

There was a dramatic rise in the incidence of rhino-orbito-cerebral mucormycosis associated with the 2021 Covid-19 wave in India. We aim to document the demographic characteristics and risk factors of a consecutive cohort of inpatients with Covid-19-associated rhino-orbito-cerebral mucormycosis (CAROM) during the surge of April–June 2021.

Methods

We included all patients of CAROM treated at our tertiary referral facility from 1 April to 14 June 2021. We prospectively gathered details with regard to Covid-19 illness and treatment, CAROM presentation, comorbid conditions and risk factors.

Results

Our prospective cohort consisted of 200 consecutive patients, of which 146 (73%) patients tested positive on the Covid-19 RT-PCR test at presentation. CAROM occurred concurrent with the Covid-19 infection in 86%, and delayed CAROM after seeming recovery from Covid-19 was seen in 14%. Covid-19 was classified as mild, moderate and severe in 54%, 33% and 13%. The surge of CAROM followed the population peak of Covid-19 infections by about 3 weeks. Advanced disease at presentation was frequent with ocular involvement in 56.6% (111/196) and central nervous system involvement in 20% (40/199). One or more comorbid conditions were identified in 191/200 (95.5%) patients. The dominant associations were with diabetes (189/200; 94.5%) and uncontrolled hyper-glycaemia (122/133; 91.7%), recent steroid use (114/ 200; 57%), which was often considered as inappropriate in dosage or duration, lymphopenia (142/176; 80.7%), and increased ferritin levels (140/160; 87.5%). No evidence supported the role of previous oxygen therapy or previous nasal swab testing as risk factors for CAROM.

Conclusion

The inpatient volumes of CAROM were noted to parallel the Covid-19 incidence curve by about 3 weeks. Covid-19 infection may directly predispose to CAROM by way of lymphopenia and increased ferritin levels. Uncontrolled hyperglycaemia is identified as a near-invariable association. Recent steroid use is noted as very frequent and was often received in excess of treatment advisories.
Cancer care continuum at a tertiary care centre in India during the Covid-19 pandemic and nationwide lockdown: Healthcare delivery through telemedicine
Authors: GOKARN ANANT , JOSHI AMIT , WADASADAWALA TABASSUM , GULIA SEEMA , WAKLE SWAPNIL , SINGH ANUJ , TILODA APOORVA , SINGH ABHISHEK , CHAKRABORTY DEBANJAN , SUBRAMANI VIGNESH , BAJAJ POOJA , CHINTALA SRAVAN KUMAR , PATHAK BHAGYASHREE , SIMHA VIJAI , SOOD SAHIL , KALRA BABUSHA , BHANDARI MANASI , AVONU SALE , ELAMARTHY PRAHALAD , DAS SHASANKA , DASH RABI SHANKAR , JANSARI JAYSHREE , SEHRA NISHTHA , VISPUTE TEJAS , THAKUR JAGRUTI , GAWADE LAXMAN , VEMURI CHANDANA , NEKKANTI SIDDHARTHA , BANSOD YOGESH , CHAUHAN LOVEDEEP , CHHATRALA RENISH , GURUKEERTHI B. , SHANKAR RAVI , NARAYANAN R. , PREETI V. , SHETTY PREETHI , DIKSHIT RAJESH , KHATTRY NAVIN , GUPTA SUDEEP , GOEL NISHU , BADWE RAJENDRA A.
Published: November 2022

Background

The Covid-19 pandemic and subsequent lockdown in India caused disruptions in cancer treatment due to the restriction on movement of patients. We aimed to maintain continuity in cancer treatment during the lockdown through teleconsultations. We tried to reach out to our patients using telephonic consultations by establishing a Teleconsult Centre facility run by a team of doctors and patient navigators.

Methods

We telephonically contacted all patients who had outpatient appointments from 23 March to 30 April 2020 at our centre through the Teleconsult Centre to understand their current circumstances, feasibility of follow-up, local resources and offered best possible alternatives to continue cancer treatment, if required.

Results

Of the 2686 patients scheduled for follow-up during this period, we could contact 1783 patients in 9 working days. Through teleconsultations, we could defer follow-ups of 1034 patients (57.99%, 95% confidence interval [CI] 55.6%–60.3%), thus reducing the need for patients to travel to the hospital. Change in systemic therapy was made in 75 patients (4.2%, 95% CI 3.3%–5.2%) as per the requirements and available resources. Symptoms suggestive of disease progression were picked up in 12 patients (0.67%, 95% CI 0.35%–1.17%), who were advised to meet local physicians.

Conclusion

Our study suggests that the majority of patients on follow-up can be managed with teleconsultation in times of crisis. Teleconsultation has the potential of being one of the standard methods of patient follow-up even during periods of normalcy.
Mental health status of healthcare providers during the Covid-19 pandemic: A cross-sectional study across India
Authors: RAMDURG SANTOSH , MUDANUR SUBHASHCHANDRA R. , BENTOOR SANJEEV , MUDANUR NIKHIL S.
Published: November 2022

Background

From the beginning of the Covid-19 pandemic, studies have observed an increased prevalence of psychological symptoms in the general population and healthcare providers. We studied the prevalence of psychological symptoms among the latter.

Methods

We did this study using a self-administered questionnaire among healthcare providers across India who were involved in caring/treating patients. The questionnaire collected information on demographics, Depression, Anxiety and Stress Scales (DASS-21) and semi-structured questions related to the Covid-19 pandemic.

Results

A total of 612 healthcare providers participated in the study; 254 were doctors of various specialties and 358 were nursing care-providers. According to the DASS-21 assessment, the prevalence of depression was 12.4%, anxiety was 19.1% and stress was 10.8%. The prevalence of psychological problems was more among nursing staff compared to doctors (depression risk ratio [RR] 2.4, anxiety RR 1.73 and stress RR 2.93) and they were equal among both genders (depression RR 1.05, anxiety RR 1.06 and stress RR 1.21).

Conclusions

Our study shows that there is a higher prevalence of depression, anxiety and stress among healthcare providers, particularly among nursing care-providers. We suggest psychological interventions to nursing care-providers and also those who are vulnerable among doctors, to improve their mental health status.
Direct Imaging of Micrometer Thick Interfaces in Salt-Salt Aqueous Biphasic Systems
Authors: Degoulange Damien , Pandya Raj , Deschamps Michael , Skiba Dhyllan , Gallant Betar , Gigan Sylvain , de Aguiar Hilton , Grimaud Alexis
Published: November 2022

Unlike the interface between two immiscible electrolyte solutions (ITIES) formed between water and polar solvents, molecular understanding of the liquid-liquid interface formed for aqueous biphasic systems (ABSs) is relatively limited and mostly relies on surface tension measurements and thermodynamic models. Here, high-resolution Raman imaging is used to provide spatial and chemical resolution of the interface of LiCl-LiTFSI-water and HCl-LiTFSI-water, prototypical salt-salt ABSs found in a range of electrochemical applications. The concentration profiles of both TFSI anions and water are found to be sigmoidal, in agreement with an increasing surface tension as a function of concentration, both being typical of a negative adsorption mechanism. More striking, however, is the length at which the concentration profiles extend, ranging from 11 to 2 m with increasing concentrations, compared to a few nanometers for ITIES. We thus reveal that unlike ITIES, salt-salt ABSs do not have a molecularly sharp interface but rather form an interphase with a gradual change of environment from one phase to the other. This knowledge represents a major stepping-stone in the understanding of aqueous interfaces, key for mastering ion or electron transfer dynamics in a wide range of biological and technological settings including novel battery technologies such as membraneless redox flow and dual ion batteries.
The Interaction between TEMPO Radicals and Gold Surfaces
Authors: Zhang Haitao , Herrmann Carmen
Published: November 2022

Organic radical molecules are, due to their relevance for spintronics and fundamental interest, studied in mechanically controlled break junctions. It is often assumed that organic radicals are anchored to the gold electrodes by designated linker thiol groups, with the radical substituents far from the electrodes. However, the interaction between a radical substituent and gold, in addition to the functional groups designed for anchoring the molecule, could influence the interaction between the whole molecule and the surface. Although some relevant experiments have been reported, the findings are inconsistent. To elucidate a possible influence, we discuss the interaction between a commonly used nitroxyl radical, (2,2,6,6-tetramethylpiperidin-1-yl)oxidanyl (TEMPO), with gold electrode surfaces by density functional theory methods, combined with empirical dispersion corrections. Within the uncertainty inherent in this methodology, our results suggest that the interaction between TEMPO and gold is made up of two competitive and complementary contributions: direct binding between the nitroxyl and gold adatoms, and dispersion interactions between bulky methyl groups and the surface (which is more pronounced for clean Au(111) surfaces but also prevents direct binding in case). Importantly, the overall interaction is not negligible and is even comparable to some commonly used anchoring groups (e.g., amino groups). This may have consequences for interpreting conductance and magnetoresistance data on organic radicals in molecular junctions.
A Redox Transmetalation Step in Nickel-Catalyzed C-C Coupling Reactions
Authors: Green Kerry-Ann , Honeycutt Aaron , Ciccone Sierra , Grice Kyle , Petersen Jeffrey , Hoover Jessica
Published: November 2022

Ni-catalyzed C-H functionalization reactions are becoming efficient routes to access a variety of functionalized arenes, yet the mechanisms of these catalytic C-C coupling reactions are not well understood. Here we report the catalytic and stoichiometric arylation reactions of a nickel(II) metallacycle. Treatment of this species with silver(I)-aryl complexes results in facile arylation, consistent with a redox transmetalation step. Additionally, treatment with electrophilic coupling partners generates new C-C and C-S bonds. We anticipate that this redox transmetalation step may be relevant to other coupling reactions that employ silver salts as additives.
Cobertura periodística de la migración en Ecuador durante los estados de excepción del 2020
Authors: Márquez-Domínguez Carmelo , Asprino Salas Marilena Coromoto , Cornejo Dávila Lizbeth Anahí
Published: November 2022

Hay que esperar a que ocurran catástrofes extraordinarias, como la crisis sanitaria ocasionada por el COVID-19, para apreciar un enfoque de los derechos humanos en la información periodística. Con el fin de estudiar la cobertura periodística en Ecuador sobre la inmigración durante los estados de excepción decretados en 2020, se plantea un método analítico y comparativo con un enfoque mixto: por un lado, se recopiló toda la producción documental a fin de construir el estado del arte; por otro, se extrajo el producto periodístico sobre migración y movilidad humana publicado en las ediciones digitales de El Comercio y El Universo para, después, hacer un análisis del contenido. Los resultados arrojan encuadres neutros, con un tratamiento sin un enfoque de derechos humanos ni un lenguaje inclusivo, lo que se traduce en una preferencia por titulares y géneros informativos; una escasa presencia de infografías, datos estadísticos y elementos transmedia; una despersonalización general de la firma periodística y un predominio de las fuentes oficiales. Además, la temática apunta a una petición de orden —frente al caos— y los sujetos señalados son los inmigrantes venezolanos.
Accesibilidad de los contenidos televisivos para personas con discapacidad: limitaciones y propuestas de mejora
Authors: García-Prieto Victoria , Figuereo-Benítez Juan C.
Published: November 2022

El acceso a la información es un derecho fundamental que adquiere relevancia en el caso de la televisión, especialmente la pública, por su misión de servicio público e inclusión social. Garantizar el acceso de las personas con discapacidad a sus contenidos audiovisuales resulta imprescindible para alcanzar los objetivos de calidad de vida y plena igualdad de oportunidades. Para ello, la legislación internacional y nacional establece que los contenidos televisivos deben incluir subtítulos, audiodescripción y lengua de signos. Sin embargo, que las televisiones cumplan con los requisitos legales no significa necesariamente que se satisfagan las necesidades de los televidentes con discapacidad. Este estudio exploratorio cualitativo se enmarca en Reino Unido y España, y analiza la situación de la accesibilidad en la televisión pública a través de entrevistas cualitativas a trece personas expertas provenientes del movimiento asociativo, la televisión y el ámbito académico. Enfrentando las posiciones de los distintos sectores se demuestra que los niveles de accesibilidad y su calidad son inferiores a los deseados, impidiendo el acceso universal de las personas con discapacidad visual y/o auditiva. Asimismo, desde diferentes ángulos, se plantean alternativas de mejora a las principales demandas de los receptores.
Tatakae: El giro espacial del animé en el contexto de la protesta social
Authors: Vargas Vargas Joaquín
Published: November 2022

Caminando por las calles del centro de Santiago de Chile, posterior a la toma y ocupación del espacio que se vivió durante la revuelta social de octubre del 2019, se observa la serie de intervenciones murales que hasta el día de hoy mantienen viva una memoria y denuncia sobre la violencia de Estado, confrontando el silencio y censura del gobierno sobre las violaciones a los derechos humanos ocurridos durante aquellos meses. Entre estos, no es raro ver grabados y rayados que hacen referencia a la cultura de consumo, sobre todo aquellos pertenecientes a series de animación japonesa (animé) y manga (cercano al cómic japonés), realizados por organizaciones como Otaku Antifascista o Tatakae Chile. No obstante, el fenómeno llama la atención por cuanto se replica no solo en el contexto de la protesta en Chile, sino también en países como Perú y Bolivia, donde los fans del animé, ampliamente reconocidos como otakus, construyen un nuevo lenguaje de la protesta social. El presente ensayo reflexiona sobre esta articulación, evaluando el desplazamiento espacial que sufre el referente otaku desde su consumo en el espacio privado (cerrado) al público (mensaje político), siguiendo las lógicas de la teoría espacial.
Options for overcoming implantation failures in infertility of uterine genesis due to chronic endometritis. A review
Authors: Krasnopolskaya Kseniya V. , Mikhaleva Liudmila M. , Orazov Mekan R. , Dolgov Evgeny D.
Published: November 2022

Chronic endometritis remains one of the most controversial issues of modern gynecology. The high relevance of research in this area is confirmed not only by the high prevalence but also by the extremely negative impact of this disease on the reproductive potential of patients. The complexity of the pathogenesis mechanism of the chronic inflammatory process of the endometrium stimulates the genuine interest of the world gynecological community to study the main patterns of endometrial receptor disorder, including implantation status and repeated reproductive failures. In this regard, it is essential to summarize the accumulated results of worldwide research to find the most optimal and effective diagnostic and therapeutic approaches.
Complete repeat cytoreduction under regional anesthesia in a patient with myasthenia gravis: a clinical case
Authors: Chukhnov Sergey A.
Published: November 2022

The article summarizes the published data on the prevalence, pathogenesis, features of clinical presentation, and treatment of myasthenia gravis and myasthenic crises. Particular attention is paid to the anesthesia method choice and perioperative management of patients with myasthenia gravis. A clinical case of successful combined spinal-epidural anesthesia for complete repeat cytoreductive surgery in a patient with moderate myasthenia gravis is presented.
Kalp Yetmezlikli Hastalarda CHA2DS2-VASc Skoru ve Sol Ventrikül Apikal Trombozu İlişkisi
Authors: ALSANCAK Yakup , SERTDEMİR Ahmet , DURAN Mustafa , SARI Hasan , GÜRBÜZ Ahmet Seyfeddin , KALELİ Muhammed Fatih
Published: November 2022

Amaç: Sol ventrikül apikal trombüsü (LVAT), akut miyokard enfarktüsü sonrası hastalarda artmış morbidite ve mortalite ile ilişkilidir. Bu çalışmada sol ventrikül apikal trombozu ile CHA2DS2-VASc skorlama sistemi arasındaki ilişkiyi değerlendirmek amaçlandı.Materyal ve Metot: Bu çalışmaya Ocak 2010 ile Ocak 2020 arasında kliniğimizde takip edilen 456 (LVAT'li 146, kontrol grubu ile benzer demografik özelliklere sahip ventriküler trombozu olmayan 300) hasta dahil edildi.Bulgular: Tüm çalışma popülasyonunda tanı sırasında ortalama CHA2DS2-VASc skoru 3,05±1,34 olarak hesaplandı ve CHA2DS2-VASc skoru LVAT'de istatistiksel olarak daha yüksekti (p= 0,029). LVAT grubunda CHA2DS2-VASc skoru 2'nin üzerinde olan hasta sayısı %79 iken kontrol grubunda %55 idi (p <0,001). Ejeksiyon fraksiyonu gruplar arasında benzerdi, ancak LVAT grubundaki hastalarda sol ventrikül diyastolik/sistolik çapları ve sol atriyum çapı daha büyüktü (sırasıyla; p=0,793, p=0,001). CHA2DS2-VASc skoru, koroner arter hastalığı varlığı LVAT için bağımsız risk faktörleriydi (sırasıyla; β= 0,385, p= 0,001, β= 0,265, p= 0,045).Sonuç: LVAT'li hastalarda CHA2DS2-VASc skoru daha yüksek olma eğilimindeydi ve daha yüksek bir CHA2DS2-VASc skoru, LVAT insidansının bağımsız bir öngördürücüsü olarak bulundu. İdiyopatik sistemik emboli öyküsü olan ve yüksek CHA2DS2-VASc skoru (≥2) olan kalp yetmezliği hastalarında sol ventrikül trombüsü akılda tutulmalıdır.
Forced Migrant: The Factors Contributing to Social Functionality of Syrian Youth
Authors: ARİFOĞLU Ahmed Taha , KOÇAK Orhan
Published: November 2022

Forced migrants face many problems during the forced migration process. At the forefront of these problems is the negative impact of the forced migration process on their social functionality. The aim of this study is to investigate the factors contributing to the social functionality of Syrian youth under temporary protection status in Turkey. The sample of the study consisted of 326 young Syrian forced migrants aged 18 to 29 who are under temporary protection status in Turkey and was conducted in Istanbul, Sakarya, and Izmir. The study was carried out with the quantitative method and snowball sampling. The obtained data were evaluated by correlation, mediator and moderator analysis methods. According to the data obtained in the study, Perceived social support and satisfaction with life have a significant effect on social functionality. Satisfaction with life has a full mediating effect on the effect of perceived social support on social functionality. In other words, as a Syrian youth's perceived social support grows, so does their social functionality, and satisfaction with life has a full mediating positive effect on this relationship. Planning activity, which is an active coping strategy, has a positive moderating effect on the connection between perceived social support and social functionality, according to this model. In this context, social work practice with a multidimensional community is recommended.