bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplemental Figures 1 - 2 from Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis
Authors: Wettersten Hiromi I. , Hakimi A. Ari , Morin Dexter , Bianchi Cristina , Johnstone Megan E. , Donohoe Dallas R. , Trott Josephine F. , Aboud Omran Abu , Stirdivant Steven , Neri Bruce , Wolfert Robert , Stewart Benjamin , Perego Roberto , Hsieh James J. , Weiss Robert H.
Published: April 2023

1. Cytosolic lipid storage is decreased in RCC tissue with increasing tumor grade 2. Glutamine depletion attenuates RCC cell viability, decreases the anti-oxidant system, and results in evidence of increased oxidative stress
Supplementary Figures S1 through S6 and Supplementary Tables S1 and S2 from The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers
Authors: Leonard Brandon , McCann Jennifer L. , Starrett Gabriel J. , Kosyakovsky Leah , Luengas Elizabeth M. , Molan Amy M. , Burns Michael B. , McDougle Rebecca M. , Parker Peter J. , Brown William L. , Harris Reuben S.
Published: April 2023

Table S1. Cell Line Information. Table S2. ChIP reagents. Figure S1. APOBEC3B upregulation by PMA in multiple cell lines. Figure S2. APOBEC3 mRNA levels in PMA-treated MCF10A. Figure S3. Extended timecourse for PMA induction of APOBEC3B. Figure S4. Viability controls for MCF10A cells treated with small molecule inhibitors. Figure S5. Expanded ChIP data for MCF10A cells treated with PMA alone or in combination with AEB071. Figure S6. Viability controls for cancer cell lines treated with AEB071.
Supplemental Figure S7 from Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase Inhibitors by Multimodality Molecular Imaging in Living Subjects
Authors: Chan C.T. , Qi J. , Smith W. , Paranol R. , Mazitschek R. , West N. , Reeves R. , Chiosis G. , Schreiber S.L. , Bradner J.E. , Paulmurugan R. , Gambhir S.S.
Published: April 2023

Supplemental Figure S7. Inhibition of UKE-1 cell proliferation by the lead HDAC inhibitor 1A12 alone and in combination with the Doxorubicin and Hsp90 inhibitor PU-H71.
Supplementary Figure S3 from Definition of Prostaglandin E2–EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth
Authors: Ma Xiaojun , Aoki Tomohiro , Tsuruyama Tatsuaki , Narumiya Shuh
Published: April 2023

Supplementary Figure S3. NF-κB activation in neutrophils and EP2-dependent expression of pro-inflammatory genes.
Supplemental Figure S3 from Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase Inhibitors by Multimodality Molecular Imaging in Living Subjects
Authors: Chan C.T. , Qi J. , Smith W. , Paranol R. , Mazitschek R. , West N. , Reeves R. , Chiosis G. , Schreiber S.L. , Bradner J.E. , Paulmurugan R. , Gambhir S.S.
Published: April 2023

Supplemental Figure S3. Syntheses and characterization of lead HDAC inhibitors.
Supplementary Figure S2 from Definition of Prostaglandin E2–EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth
Authors: Ma Xiaojun , Aoki Tomohiro , Tsuruyama Tatsuaki , Narumiya Shuh
Published: April 2023

Supplementary Figure S2. Specificity of anti-EP2 antibody used and the major subpopulation of Gr-1+ cells in the colon.
Supplemental Figure S1 from Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase Inhibitors by Multimodality Molecular Imaging in Living Subjects
Authors: Chan C.T. , Qi J. , Smith W. , Paranol R. , Mazitschek R. , West N. , Reeves R. , Chiosis G. , Schreiber S.L. , Bradner J.E. , Paulmurugan R. , Gambhir S.S.
Published: April 2023

Supplemental Figure S1. Effect of HDAC and Hsp90 inhibitors on Hsp90 (α/β)/p23 interactions.
Supplementary Figure Legends from Definition of Prostaglandin E2–EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth
Authors: Ma Xiaojun , Aoki Tomohiro , Tsuruyama Tatsuaki , Narumiya Shuh
Published: April 2023

Supplementary Figure Legends. Legend for Supplementary Figures S1-S4.
Supplemental Figure Legends from Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase Inhibitors by Multimodality Molecular Imaging in Living Subjects
Authors: Chan C.T. , Qi J. , Smith W. , Paranol R. , Mazitschek R. , West N. , Reeves R. , Chiosis G. , Schreiber S.L. , Bradner J.E. , Paulmurugan R. , Gambhir S.S.
Published: April 2023

Legends for Supplemental Figures S1-S8.
Supplemental video 1 from ITPR1 Protects Renal Cancer Cells against Natural Killer Cells by Inducing Autophagy
Authors: Messai Yosra , Noman Muhammad Zaeem , Hasmim Meriem , Janji Bassam , Tittarelli Andrés , Boutet Marie , Baud Véronique , Viry Elodie , Billot Katy , Nanbakhsh Arash , Ben Safta Thouraya , Richon Catherine , Ferlicot Sophie , Donnadieu Emmanuel , Couve Sophie , Gardie Betty , Orlanducci Florence , Albiges Laurence , Thiery Jerome , Olive Daniel , Escudier Bernard , Chouaib Salem
Published: April 2023

Supplemental video 1. 786-0 cells described in Figure 3B were recorded by time-lapse video microscopy
Supplementary Table 2 from CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus
Authors: Russell Mike R. , Penikis Annalise , Oldridge Derek A. , Alvarez-Dominguez Juan R. , McDaniel Lee , Diamond Maura , Padovan Olivia , Raman Pichai , Li Yimei , Wei Jun S. , Zhang Shile , Gnanchandran Janahan , Seeger Robert , Asgharzadeh Shahab , Khan Javed , Diskin Sharon J. , Maris John M. , Cole Kristina A.
Published: April 2023

Full Table for the CASC15-S Cox Statistical Model.
Supplementary Figure 8 from CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus
Authors: Russell Mike R. , Penikis Annalise , Oldridge Derek A. , Alvarez-Dominguez Juan R. , McDaniel Lee , Diamond Maura , Padovan Olivia , Raman Pichai , Li Yimei , Wei Jun S. , Zhang Shile , Gnanchandran Janahan , Seeger Robert , Asgharzadeh Shahab , Khan Javed , Diskin Sharon J. , Maris John M. , Cole Kristina A.
Published: April 2023

Cell viability assays for neuroblastoma cell lines stably depleted of CASC15-S.
Supplementary Table 1 from High-Frequency Targetable EGFR Mutations in Sinonasal Squamous Cell Carcinomas Arising from Inverted Sinonasal Papilloma
Authors: Udager Aaron M. , Rolland Delphine C.M. , McHugh Jonathan B. , Betz Bryan L. , Murga-Zamalloa Carlos , Carey Thomas E. , Marentette Lawrence J. , Hermsen Mario A. , DuRoss Kathleen E. , Lim Megan S. , Elenitoba-Johnson Kojo S.J. , Brown Noah A.
Published: April 2023

Sinonasal Papilloma Clinical and Genotypic Data.
Supplementary Figure 7 from CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus
Authors: Russell Mike R. , Penikis Annalise , Oldridge Derek A. , Alvarez-Dominguez Juan R. , McDaniel Lee , Diamond Maura , Padovan Olivia , Raman Pichai , Li Yimei , Wei Jun S. , Zhang Shile , Gnanchandran Janahan , Seeger Robert , Asgharzadeh Shahab , Khan Javed , Diskin Sharon J. , Maris John M. , Cole Kristina A.
Published: April 2023

Depletion of the long isoform of CASC15 does not impact neuroblastoma cell viability.
Supplementary Figure 5 from CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus
Authors: Russell Mike R. , Penikis Annalise , Oldridge Derek A. , Alvarez-Dominguez Juan R. , McDaniel Lee , Diamond Maura , Padovan Olivia , Raman Pichai , Li Yimei , Wei Jun S. , Zhang Shile , Gnanchandran Janahan , Seeger Robert , Asgharzadeh Shahab , Khan Javed , Diskin Sharon J. , Maris John M. , Cole Kristina A.
Published: April 2023

Additional expression data for CASC15 isoforms in neuroblastoma cell lines and patients.
Supplementary Figure 4 from CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus
Authors: Russell Mike R. , Penikis Annalise , Oldridge Derek A. , Alvarez-Dominguez Juan R. , McDaniel Lee , Diamond Maura , Padovan Olivia , Raman Pichai , Li Yimei , Wei Jun S. , Zhang Shile , Gnanchandran Janahan , Seeger Robert , Asgharzadeh Shahab , Khan Javed , Diskin Sharon J. , Maris John M. , Cole Kristina A.
Published: April 2023

rs6939340 genotype and expression of 6p22.3 gene products.
Supplementary Table S3 from Adaptive Responses to Dasatinib-Treated Lung Squamous Cell Cancer Cells Harboring DDR2 Mutations
Authors: Bai Yun , Kim Jae-Young , Watters January M. , Fang Bin , Kinose Fumi , Song Lanxi , Koomen John M. , Teer Jamie K. , Fisher Kate , Chen Yian Ann , Rix Uwe , Haura Eric B.
Published: April 2023

Supplementary Table S3. Dasatinib-regulated pY-peptides identified from both cell lines (n=73).
Supplementary Table 2 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: April 2023

Supplementary Table 2: Primers for mouse quantitative RT-PCR (SYBR)
Supplemental Figures 1-7 from Erlotinib Pretreatment Improves Photodynamic Therapy of Non–Small Cell Lung Carcinoma Xenografts via Multiple Mechanisms
Authors: Gallagher-Colombo Shannon M. , Miller Joann , Cengel Keith A. , Putt Mary E. , Vinogradov Sergei A. , Busch Theresa M.
Published: April 2023

Supplemental Figures 1-7. Supplemental Figure 1. Erlotinib does not alter oxygenation of tumors Supplemental Figure 2. Erlotinib increases in vivo tumor cell death at delayed timepoints. Supplemental Figure 3. In vivo imaging of tumor perfusion is well correlated with ex vivo imaging of the excised tumor. Supplemental Figure 4. VEGF levels decrease in A549 tumors with pre-PDT administration of erlotinib Supplemental Figure 5. Western blot analysis Supplemental Figure 6. BPD levels increase Supplemental Figure 7. A single-dose of erlotinib augments PDT-induced cytotoxicity.
Supplementary Figure 4 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: April 2023

Supplementary Figure 4: Human PAD2 expression, along with Mouse Pad1, Pad2, Pad3, and Pad4 expression levels in transgenic mice
Supplementary Tables 1 and 2 from CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer
Authors: Karakasheva Tatiana A. , Waldron Todd J. , Eruslanov Evgeniy , Kim Sang-Bae , Lee Ju-Seog , O'Brien Shaun , Hicks Philip D. , Basu Devraj , Singhal Sunil , Malavasi Fabio , Rustgi Anil K.
Published: April 2023

Supplementary Tables 1 and 2. Supplementary Table 1. List of the genes differentially expressed in CD11b+Gr1+ splenocytes from tumor-bearing, compared to control mice. Supplementary Table 2. List of the genes differentially expressed in CD38high, compared to CD38low, CD11b+Gr1+ splenocytes from tumor-bearing mice.
Supplementary Figure 2 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: April 2023

Supplementary Figure 2: Control immunohistochemical analysis (Rabbit IgG) of epidermis in transgenic mice (MMTV-FP2+)
Supplementary Figure 1 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: April 2023

Supplementary Figure 1: MMTV-FLAG-PAD2 expression in the mammary gland
Supplementary Tables S1-S10 from Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance
Authors: Gurden Mark D. , Westwood Isaac M. , Faisal Amir , Naud Sébastien , Cheung Kwai-Ming J. , McAndrew Craig , Wood Amy , Schmitt Jessica , Boxall Kathy , Mak Grace , Workman Paul , Burke Rosemary , Hoelder Swen , Blagg Julian , Van Montfort Rob L.M. , Linardopoulos Spiros
Published: April 2023

Tables of biochemical and viability assays of resistant cell clones, fractional abundance of MPS1 mutants in different human cancer cell lines and refinement statistics of crystal structures of different MPS1 domains.
Supplementary Table S2 from Tenascin-C Protects Cancer Stem–like Cells from Immune Surveillance by Arresting T-cell Activation
Authors: Jachetti Elena , Caputo Sara , Mazzoleni Stefania , Brambillasca Chiara Svetlana , Parigi Sara Martina , Grioni Matteo , Piras Ignazio Stefano , Restuccia Umberto , Calcinotto Arianna , Freschi Massimo , Bachi Angela , Galli Rossella , Bellone Matteo
Published: April 2023

Supplementary Table S2. Kegg enrichment of proteins upregulated in T cells cultured in the presence of TPIN-SCs.
Supplementary Figures S1-S7 from NKX3.1 Suppresses TMPRSS2–ERG Gene Rearrangement and Mediates Repair of Androgen Receptor–Induced DNA Damage
Authors: Bowen Cai , Zheng Tian , Gelmann Edward P.
Published: April 2023

Supplementary Figures S1-S7. AR induces chromosome conformational change juxtaposing TMPRSS2 and ERG (S1); TMPRSS2-ERG rearrangement in different NKX3.1-expressing cell lines (S2); NKX3.1 has no effects on TMPRSS2-ERG gene rearrangement in the absence of AR (S3); NKX3.1 expression and TMPRSS2-ERG rearrangement are related to histologic grade (S4); AR and NKX3.1 are recruited to break sites on TMPRSS2 and ERG genes (S5); NKX3.1 facilitates assembly of OGG1 at ERG gene break site (S6); Transcription is not required for TMPRSS2-ERG juxtaposition or rearrangement (S7).
Supplementary Table S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Authors: Faria Claudia C. , Golbourn Brian J. , Dubuc Adrian M. , Remke Marc , Diaz Roberto J. , Agnihotri Sameer , Luck Amanda , Sabha Nesrin , Olsen Samantha , Wu Xiaochong , Garzia Livia , Ramaswamy Vijay , Mack Stephen C. , Wang Xin , Leadley Michael , Reynaud Denis , Ermini Leonardo , Post Martin , Northcott Paul A. , Pfister Stefan M. , Croul Sidney E. , Kool Marcel , Korshunov Andrey , Smith Christian A. , Taylor Michael D. , Rutka James T.
Published: April 2023

Supplementary Table S1. Foretinib concentrations in mouse brain, mouse plasma and the brain-plasma ratio
Supplementary Methods from Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay–Independent Manner
Authors: Kratochvill Franz , Gratz Nina , Qualls Joseph E. , Van De Velde Lee-Ann , Chi Hongbo , Kovarik Pavel , Murray Peter J.
Published: April 2023

Description of additional methods and procedures used in the study.
Supplemental Figure S1 from Therapeutically Targetable ALK Mutations in Leukemia
Authors: Maxson Julia E. , Davare Monika A. , Luty Samuel B. , Eide Christopher A. , Chang Bill H. , Loriaux Marc M. , Tognon Cristina E. , Bottomly Daniel , Wilmot Beth , McWeeney Shannon K. , Druker Brian J. , Tyner Jeffrey W.
Published: April 2023

ALK is expressed in the B-ALL sample with the ALK A348D mutation.
supplementary figure 3 from Microenvironmental Remodeling as a Parameter and Prognostic Factor of Heterogeneous Leukemogenesis in Acute Myelogenous Leukemia
Authors: Kim Jin-A , Shim Jae-Seung , Lee Ga-Young , Yim Hyeon Woo , Kim Tae-Min , Kim Myungshin , Leem Sun-Hee , Lee Jong-Wook , Min Chang-Ki , Oh Il-Hoan
Published: April 2023

supplementary figure 3: immunohistochemical analysis of CXCL-12 expression in AML bone marrow.
Supplemental Movie 2 from Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and Metastasis
Authors: Mumblat Yelena , Kessler Ofra , Ilan Neta , Neufeld Gera
Published: April 2023

Supplemental Movie 2. A time lapse movie showing the effect FR-Sema3C on the proliferation of human umbilical vein derived endothelial cells (HUVEC).
Supplemental Movie 1 from Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and Metastasis
Authors: Mumblat Yelena , Kessler Ofra , Ilan Neta , Neufeld Gera
Published: April 2023

Supplemental Movie 1. A time lapse movie of proliferating human umbilical vein derived endothelial cells (HUVEC)
Supplementary Table 1 from PML/RARα-Regulated miR-181a/b Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia
Authors: Bräuer-Hartmann Daniela , Hartmann Jens-Uwe , Wurm Alexander Arthur , Gerloff Dennis , Katzerke Christiane , Verga Falzacappa Maria Vittoria , Pelicci Pier Giuseppe , Müller-Tidow Carsten , Tenen Daniel G. , Niederwieser Dietger , Behre Gerhard
Published: April 2023

Genetic and morphological characteristics of APL patients used for miR-181a/b expression analysis.
Supplementary Table S1 from Neuroendocrine Transdifferentiation in Human Prostate Cancer Cells: An Integrated Approach
Authors: Cerasuolo Marianna , Paris Debora , Iannotti Fabio A. , Melck Dominique , Verde Roberta , Mazzarella Enrico , Motta Andrea , Ligresti Alessia
Published: April 2023

Supplementary Table S1. Topology-based pathway analysis.
Supplementary Figure S1 from miR-25 Modulates Invasiveness and Dissemination of Human Prostate Cancer Cells via Regulation of αv- and α6-Integrin Expression
Authors: Zoni E. , van der Horst G. , van de Merbel A.F. , Chen L. , Rane J.K. , Pelger R.C.M. , Collins A.T. , Visakorpi T. , Snaar-Jagalska B.E. , Maitland N.J. , van der Pluijm G.
Published: April 2023

Supplementary Figure S1. ALDHhigh prostate cancer cells display enhanced colony formation and migration compared to ALDHlow cells.
Supplementary Tables S11 and S12 for Dang et al from ΔNp63α Promotes Breast Cancer Cell Motility through the Selective Activation of Components of the Epithelial-to-Mesenchymal Transition Program
Authors: Dang Tuyen T. , Esparza Matthew A. , Maine Erin A. , Westcott Jill M. , Pearson Gray W.
Published: April 2023

Supplementary tables related to reagents used.
Supplementary Table S6 from Activation Status of the Pregnane X Receptor Influences Vemurafenib Availability in Humanized Mouse Models
Authors: MacLeod A. Kenneth , McLaughlin Lesley A. , Henderson Colin J. , Wolf C. Roland
Published: April 2023

Pharmacokinetic parameters of vemurafenib in huPXR/huCAR/huCYP3A4/3A7 mice pre-treated with RIF and elacridar.
Supplementary Table S1 from Activation Status of the Pregnane X Receptor Influences Vemurafenib Availability in Humanized Mouse Models
Authors: MacLeod A. Kenneth , McLaughlin Lesley A. , Henderson Colin J. , Wolf C. Roland
Published: April 2023

Apparent kinetic parameters of formation of OH-vemurafenib.
Supplementary Figure S5 from Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b
Authors: Vasilyeva Aksana , Durmus Selvi , Li Lie , Wagenaar Els , Hu Shuiying , Gibson Alice A. , Panetta John C. , Mani Sridhar , Sparreboom Alex , Baker Sharyn D. , Schinkel Alfred H.
Published: April 2023

Nonlinear mixed-effects modeling of sorafenib plasma concentrations in wildtype and Abcc2(-/-) mice.
Supplementary Figure S7 from Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells
Authors: Vilgelm Anna E. , Pawlikowski Jeff S. , Liu Yan , Hawkins Oriana E. , Davis Tyler A. , Smith Jessica , Weller Kevin P. , Horton Linda W. , McClain Colt M. , Ayers Gregory D. , Turner David C. , Essaka David C. , Stewart Clinton F. , Sosman Jeffrey A. , Kelley Mark C. , Ecsedy Jeffrey A. , Johnston Jeffrey N. , Richmond Ann
Published: April 2023

Supplementary Figure S7. Results of the flow cytometric analysis of indicated populations of leukocytes in SK-Mel5 tumors grown in BALB/C nu/Foxn1 athymic nude mice.
Supplementary Figure S2 from Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b
Authors: Vasilyeva Aksana , Durmus Selvi , Li Lie , Wagenaar Els , Hu Shuiying , Gibson Alice A. , Panetta John C. , Mani Sridhar , Sparreboom Alex , Baker Sharyn D. , Schinkel Alfred H.
Published: April 2023

Metabolism and urinary excretion of sorafenib in wildtype and Abcc2(-/-) mice.
Supplementary Table 2 from Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity
Authors: Caruso Hillary G. , Hurton Lenka V. , Najjar Amer , Rushworth David , Ang Sonny , Olivares Simon , Mi Tiejuan , Switzer Kirsten , Singh Harjeet , Huls Helen , Lee Dean A. , Heimberger Amy B. , Champlin Richard E. , Cooper Laurence J.N.
Published: April 2023

Ratio of CD4 and CD8 on Cetux-CAR+ and Nimo-CAR+ T cells
Supplementary Figure 4 from Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity
Authors: Caruso Hillary G. , Hurton Lenka V. , Najjar Amer , Rushworth David , Ang Sonny , Olivares Simon , Mi Tiejuan , Switzer Kirsten , Singh Harjeet , Huls Helen , Lee Dean A. , Heimberger Amy B. , Champlin Richard E. , Cooper Laurence J.N.
Published: April 2023

Surface expression of CAR during co-culture with tEGFR+ EL4 or CAR-L+ EL4
Supplementary Table S6: Mass spectrometry lipidomics / metabolomics data from Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids
Authors: Southam Andrew D. , Khanim Farhat L. , Hayden Rachel E. , Constantinou Julia K. , Koczula Katarzyna M. , Michell Robert H. , Viant Mark R. , Drayson Mark T. , Bunce Chris M.
Published: April 2023

Mass spectrometry data: glycerol 3-phosphate and glycerolipids
Supplementary Figures S1-S12 from Dll4 Blockade in Stromal Cells Mediates Antitumor Effects in Preclinical Models of Ovarian Cancer
Authors: Kuhnert Frank , Chen Guoying , Coetzee Sandra , Thambi Nithya , Hickey Carlos , Shan Jing , Kovalenko Pavel , Noguera-Troise Irene , Smith Eric , Fairhurst Jeanette , Andreev Julian , Kirshner Jessica R. , Papadopoulos Nicholas , Thurston Gavin
Published: April 2023

Supplementary Figure S1: Correlation of REGN421 serum concentrations and anti-HT1080 tumor activity Supplementary Figure S2: The potent anti-tumor activity of targeting Dll4 in ovarian xenograft models is dependent on blocking stromal Dll4 Supplementary Figure S3: Dll4 antibody REGN1035 treatment induces abnormal tumor vessels in ovarian cancer xenograft models Supplementary Figure S4: Dll4 expression in ovarian cancer xenograft models is restricted to the tumor vasculature Supplementary Figure S5: Notch receptor expression in ovarian cancer xenograft models Supplementary Figure S6: Notch signaling in TOV-112D cells is mediated predominantly by Notch1 Supplementary Figure S7: Combined blockade of Dll4 and VEGF reverses liver vascular changes induced by Dll4 blockade alone Supplementary Figure S8: Dll4 is expressed in the endothelium of adult heart and liver Supplementary Figure S9: Notch1 signaling activity in heart and liver is dependent on Dll4 Supplementary Figure S10: Pericyte coverage in ovarian xenograft tumors is unaltered in response to anti-Dll4 antibody treatment Supplementary Figure S11: Direct contact between endothelial and tumor cells in TOV-112D tumors Supplementary Figure S12: Direct contact between endothelial and tumor cells in A2780 tumors
Supplemental Figures 1-6 from Akt Kinase-Interacting Protein 1 Signals through CREB to Drive Diffuse Malignant Mesothelioma
Authors: Yamada Tadaaki , Amann Joseph M. , Fukuda Koji , Takeuchi Shinji , Fujita Naoya , Uehara Hisanori , Iwakiri Shotaro , Itoi Kazumi , Shilo Konstantin , Yano Seiji , Carbone David P.
Published: April 2023

Supplemental Figures 1-6. Sup. Figure 1: The effect of knockdown for Aki1 and EGFR on mesothelioma cells. Sup. Figure 2: The knockdown of Aki1 and CREB1 in mesothelioma cells. Sup. Figure 3: The knockdown of Aki1 or CREB1 by siRNA on the cell viability of mesothelial cells. Sup. Figure 4: Schema showing the role of Aki1 in DMM cells. Sup. Figure 5: p-CREB and Aki1 expression in DMM vary in intensity. Sup. Figure 6: Expression of pCREB and Aki1 in DMM histological subtypes.
Figure Legends for Supplementary Figures S1-S12 from Dll4 Blockade in Stromal Cells Mediates Antitumor Effects in Preclinical Models of Ovarian Cancer
Authors: Kuhnert Frank , Chen Guoying , Coetzee Sandra , Thambi Nithya , Hickey Carlos , Shan Jing , Kovalenko Pavel , Noguera-Troise Irene , Smith Eric , Fairhurst Jeanette , Andreev Julian , Kirshner Jessica R. , Papadopoulos Nicholas , Thurston Gavin
Published: April 2023

Legends for Supplementary Figures S1-S12
Supplementary figure 4 from Decoy Receptor DcR1 Is Induced in a p50/Bcl3–Dependent Manner and Attenuates the Efficacy of Temozolomide
Authors: Mansour Nassir M. , Bernal Giovanna M. , Wu Longtao , Crawley Clayton D. , Cahill Kirk E. , Voce David J. , Balyasnikova Irina V. , Zhang Wei , Spretz Ruben , Nunez Luis , Larsen Gustavo F. , Weichselbaum Ralph R. , Yamini Bakhtiar
Published: April 2023

Supplementary figure 4. A, clonogenic assay in U87 cells treated with Fas ligand (30 ng/ml) and/or FNAb (1 μg/ml). B, clonogenic assay in U87 cells transfected with the indicated siRNA following treatment with vehicle or Fas ligand (30 ng/ml). Data is normalized to vehicle for each si-RNA condition. C, clonogenic assay in U87 cells expressing empty vector (EV) or HA-DcR1 following treatment with Fas ligand (30 ng/ml). *, P < 0.05. D, tumor growth curves of U87 hindlimb xenografts (n = 5 mice per group) treated with the indicated combinations of TMZ and/or NPs carrying the indicated siRNA. Treatments were given as shown. *, P < 0.05, TMZ + NP-si-DcR1 vs. TMZ + NP-si-cntl.
Suppl Table S5 from Differentiation and Loss of Malignant Character of Spontaneous Pulmonary Metastases in Patient-Derived Breast Cancer Models
Authors: Bockhorn Jessica , Prat Aleix , Chang Ya-Fang , Liu Xia , Huang Simo , Shang Meng , Nwachukwu Chika , Gomez-Vega Maria J. , Harrell J. Chuck , Olopade Olufunmilayo I. , Perou Charles M. , Liu Huiping
Published: April 2023

Suppl Table S5. Genes regulated by miR-138
Suppl Legends and Methods from Differentiation and Loss of Malignant Character of Spontaneous Pulmonary Metastases in Patient-Derived Breast Cancer Models
Authors: Bockhorn Jessica , Prat Aleix , Chang Ya-Fang , Liu Xia , Huang Simo , Shang Meng , Nwachukwu Chika , Gomez-Vega Maria J. , Harrell J. Chuck , Olopade Olufunmilayo I. , Perou Charles M. , Liu Huiping
Published: April 2023

Suppl Legends and Methods. Supplementary figure/table legends and methods
Supplementary Data Legends from Decoy Receptor DcR1 Is Induced in a p50/Bcl3–Dependent Manner and Attenuates the Efficacy of Temozolomide
Authors: Mansour Nassir M. , Bernal Giovanna M. , Wu Longtao , Crawley Clayton D. , Cahill Kirk E. , Voce David J. , Balyasnikova Irina V. , Zhang Wei , Spretz Ruben , Nunez Luis , Larsen Gustavo F. , Weichselbaum Ralph R. , Yamini Bakhtiar
Published: April 2023

Supplementary Data Legends. Legends for supplementary data presented for publication.
Supplemental Figure 1 from Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals
Authors: Cedervall Jessica , Zhang Yanyu , Huang Hua , Zhang Lei , Femel Julia , Dimberg Anna , Olsson Anna-Karin
Published: April 2023

Supplemental Figure 1: Neutrophils are effectively depleted after treatment with anti-Gr1 targeting antibodies.
Supplementary Figure Legends 1-9 from Pancreatic Cancer Combination Therapy Using a BH3 Mimetic and a Synthetic Tetracycline
Authors: Quinn Bridget A. , Dash Rupesh , Sarkar Siddik , Azab Belal , Bhoopathi Praveen , Das Swadesh K. , Emdad Luni , Wei Jun , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: April 2023

Supplementary Figure Legends 1-9
Supplementary Figure S7 from HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization
Authors: Azoitei Ninel , Diepold Kristina , Brunner Cornelia , Rouhi Arefeh , Genze Felicitas , Becher Alexander , Kestler Hans , van Lint Johan , Chiosis Gabriela , Koren John , Fröhling Stefan , Scholl Claudia , Seufferlein Thomas
Published: April 2023

Supplementary Figure S7. Pharmacologic inhibition or PRKD is sufficient to abrogate hypoxia-induced HIF-1a stabilization.
Supplemental Figures S1-S12 from Oncogenic Transformation Can Orchestrate Immune Evasion and Inflammation in Human Mesenchymal Stem Cells Independently of Extrinsic Immune-Selective Pressure
Authors: Miranda Alex , Funes Juan M. , Sánchez Nilda , Limia Celia M. , Mesa Mónica , Quezada Sergio A. , Pérez Rolando , de León Joel
Published: April 2023

Supplemental Figures S1-S12. qPCR validation of genes expression change identified by microarray analysis of HLA class I APM (S1); Increased inhibitory capacity of transformed hMSC is independent of cell lines proliferation rates (S2); Sequential transformation increases hMSC capacity to affect T-cell activation (S3); Neoplastic transformation reduces the inducible IDO and T cells chemo-attractors expression in hMSC (S4); Transformation of hMSC decreases transcription of HLA class I alleles induced by IFN-γ signaling (S5); IL-1β expression increases in hMSC following sequential transformation (S6); Neoplastic transformation of hMSC does not yield cells lysis or apoptotic cell death (S7); Transformation of human MSC leads to a variation in the expression of IL-1β signaling components (S8); IL-1β expression does not influence the proliferation rate of transformed hMSC (S9); Loss of IDO, CXCL9 and CXCL10 inducible expression is unrelated to IL-1β expression on neoplastic hMSC (S10); IL-1β production is not responsible for impaired IFN-γ response on transformed hMSC (S11); IL-1β expression increases in human fibroblast following sequential transformation (S12).
Supplementary Tables 1-3 from Mitochondrial DNA Copy Number in Peripheral Blood Cells and Risk of Developing Breast Cancer
Authors: Lemnrau Alina , Brook Mark N. , Fletcher Olivia , Coulson Penny , Tomczyk Katarzyna , Jones Michael , Ashworth Alan , Swerdlow Anthony , Orr Nick , Garcia-Closas Montserrat
Published: April 2023

Supplementary Tables 1-3. Supplementary Table 1: PCR primers and thermal cycling conditions for the mtDNA copy number assay. Supplementary Table 2 Odds ratios (OR) and 95% confidence intervals (95%CI). Supplementary Table 3 Association between breast cancer risk and quartiles of mtDNA.
Supplementary Figure S2 from HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization
Authors: Azoitei Ninel , Diepold Kristina , Brunner Cornelia , Rouhi Arefeh , Genze Felicitas , Becher Alexander , Kestler Hans , van Lint Johan , Chiosis Gabriela , Koren John , Fröhling Stefan , Scholl Claudia , Seufferlein Thomas
Published: April 2023

Supplementary Figure S2. Destabilization of PRKD2 is essential for HSP90 inhibition-triggered apoptosis in tumor cells.
Supplemental Figure 5 from The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients
Authors: Bartolini Alice , Di Paolo Daniela , Noghero Alessio , Murgia Daniele , Sementa Angela R. , Cilli Michele , Pasqualini Renata , Arap Wadih , Bussolino Federico , Ponzoni Mirco , Pastorino Fabio , Marchiò Serena
Published: April 2023

Supplemental Figure 5: NPTX2 and NPTXR are barely or not expressed in normal human tissues
Supplementary Figure S3 from A Polymer-Based Antibody–Vinca Drug Conjugate Platform: Characterization and Preclinical Efficacy
Authors: Yurkovetskiy Alexander V. , Yin Mao , Bodyak Natalya , Stevenson Cheri A. , Thomas Joshua D. , Hammond Charles E. , Qin LiuLiang , Zhu Bangmin , Gumerov Dmitry R. , Ter-Ovanesyan Elena , Uttard Alex , Lowinger Timothy B.
Published: April 2023

Sensorgrams of trastuzumab-PHF-vinca binding the hErbB2 surfaces, ~420 RU (top) and ~1320 RU (bottom).
Supplemental Figure 4 from The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients
Authors: Bartolini Alice , Di Paolo Daniela , Noghero Alessio , Murgia Daniele , Sementa Angela R. , Cilli Michele , Pasqualini Renata , Arap Wadih , Bussolino Federico , Ponzoni Mirco , Pastorino Fabio , Marchiò Serena
Published: April 2023

Supplemental Figure 4: neuroblastoma cells migrate towards microenvironment-derived cells
Supplemental Figure 1 from The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients
Authors: Bartolini Alice , Di Paolo Daniela , Noghero Alessio , Murgia Daniele , Sementa Angela R. , Cilli Michele , Pasqualini Renata , Arap Wadih , Bussolino Federico , Ponzoni Mirco , Pastorino Fabio , Marchiò Serena
Published: April 2023

Supplemental Figure 1: ephrin A1 and Î±11 integrin are barely detectable in mouse models of neuroblastoma
Supplemental Figure 6 from Evaluating Robustness and Sensitivity of the NanoString Technologies nCounter Platform to Enable Multiplexed Gene Expression Analysis of Clinical Samples
Authors: Veldman-Jones Margaret H. , Brant Roz , Rooney Claire , Geh Catherine , Emery Hollie , Harbron Chris G. , Wappett Mark , Sharpe Alan , Dymond Michael , Barrett J. Carl , Harrington Elizabeth A. , Marshall Gayle
Published: April 2023

Correlation scatter plot of a representative lung cell line (NCI-H520) showing correlation of 118 overlapping genes in non-identical Codesets. An unusual outlier is marked with a circle. Data was normalised against 8 housekeeping genes.
Supplementary Methods and References from Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating Enzymes
Authors: Lawson Ann P. , Long Marcus J.C. , Coffey Rory T. , Qian Yu , Weerapana Eranthie , El Oualid Farid , Hedstrom Lizbeth
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figures S1-S11 from Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating Enzymes
Authors: Lawson Ann P. , Long Marcus J.C. , Coffey Rory T. , Qian Yu , Weerapana Eranthie , El Oualid Farid , Hedstrom Lizbeth
Published: April 2023

Naturally occurring ITCs cause HMW-Ub accumulation in BaF3 cells (S1); Naturally occurring ITCs do not inhibit the proteasome (S2); Natural ITCs have few functional cysteine targets in cells (S3); Activity profiling shows PEITC and BITC inhibit USP9x and UCH37 (S4); PEITC and BITC inhibit DUBs at physiologically relevant concentrations (S5); Naturally occurring ITCs inhibit recombinant DUBs (S6); PEITC and BITC cause the knockdown of Mcl-1 (S7); PEITC and BITC caused an increase in Mcl-1 ubiquitination (S8); PEITC and BITC cause a knockdown of Bcr-Abl (S9); DUB inhibition is an early event in ITC-induced knockdown of Bcr-Abl in K562 cells (S10); siRNA knockdown of USP9x in BaF3/p210 cells, K562 cells and in 3T3/p210 cells results in knockdown of Bcr-Abl (S11).
Supplemental Figure 3 from Evaluating Robustness and Sensitivity of the NanoString Technologies nCounter Platform to Enable Multiplexed Gene Expression Analysis of Clinical Samples
Authors: Veldman-Jones Margaret H. , Brant Roz , Rooney Claire , Geh Catherine , Emery Hollie , Harbron Chris G. , Wappett Mark , Sharpe Alan , Dymond Michael , Barrett J. Carl , Harrington Elizabeth A. , Marshall Gayle
Published: April 2023

Correlation scatter plot of normalised log2 counts of UHR sample tested at 100ng in input volume of 5ul versus 100ng in input volume of 15ul with a CodeSet consisting of 463 including 18 housekeeping genes.
Supplementary Table 2 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer
Authors: Simó-Riudalbas Laia , Pérez-Salvia Montserrat , Setien Fernando , Villanueva Alberto , Moutinho Catia , Martínez-Cardús Anna , Moran Sebastian , Berdasco Maria , Gomez Antonio , Vidal Enrique , Soler Marta , Heyn Holger , Vaquero Alejandro , de la Torre Carolina , Barceló-Batllori Silvia , Vidal August , Roz Luca , Pastorino Ugo , Szakszon Katalin , Borck Guntram , Moura Conceição S. , Carneiro Fátima , Zondervan Ilse , Savola Suvi , Iwakawa Reika , Kohno Takashi , Yokota Jun , Esteller Manel
Published: April 2023

Supplementary Table 2. Genes that significantly change expression upon KAT6B depletion. Normalized intensities from the array in each sample and log Fold Changes from the analysis are depicted.
Supplementary Figure S5 from Blocking Tumor Necrosis Factor α Enhances CD8 T-cell–Dependent Immunity in Experimental Melanoma
Authors: Bertrand Florie , Rochotte Julia , Colacios Céline , Montfort Anne , Tilkin-Mariamé Anne-Françoise , Touriol Christian , Rochaix Philippe , Lajoie-Mazenc Isabelle , Andrieu-Abadie Nathalie , Levade Thierry , Benoist Hervé , Ségui Bruno
Published: April 2023

Supplementary Figure S5. Analysis of Treg and MDSC content in the tumors from WT and TNF-deficient mice.
Supplementary Figure 6 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer
Authors: Simó-Riudalbas Laia , Pérez-Salvia Montserrat , Setien Fernando , Villanueva Alberto , Moutinho Catia , Martínez-Cardús Anna , Moran Sebastian , Berdasco Maria , Gomez Antonio , Vidal Enrique , Soler Marta , Heyn Holger , Vaquero Alejandro , de la Torre Carolina , Barceló-Batllori Silvia , Vidal August , Roz Luca , Pastorino Ugo , Szakszon Katalin , Borck Guntram , Moura Conceição S. , Carneiro Fátima , Zondervan Ilse , Savola Suvi , Iwakawa Reika , Kohno Takashi , Yokota Jun , Esteller Manel
Published: April 2023

Supplementary Figure 6. Immunohistochemistry studies for KAT6B and acetylated K23-H3 staining according to KAT6B deletion status
Supplementary Figure S1 from Blocking Tumor Necrosis Factor α Enhances CD8 T-cell–Dependent Immunity in Experimental Melanoma
Authors: Bertrand Florie , Rochotte Julia , Colacios Céline , Montfort Anne , Tilkin-Mariamé Anne-Françoise , Touriol Christian , Rochaix Philippe , Lajoie-Mazenc Isabelle , Andrieu-Abadie Nathalie , Levade Thierry , Benoist Hervé , Ségui Bruno
Published: April 2023

Supplementary Figure S1. TNF does not modulate in vitro B16 proliferation.
Supplementary Figure 1 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer
Authors: Simó-Riudalbas Laia , Pérez-Salvia Montserrat , Setien Fernando , Villanueva Alberto , Moutinho Catia , Martínez-Cardús Anna , Moran Sebastian , Berdasco Maria , Gomez Antonio , Vidal Enrique , Soler Marta , Heyn Holger , Vaquero Alejandro , de la Torre Carolina , Barceló-Batllori Silvia , Vidal August , Roz Luca , Pastorino Ugo , Szakszon Katalin , Borck Guntram , Moura Conceição S. , Carneiro Fátima , Zondervan Ilse , Savola Suvi , Iwakawa Reika , Kohno Takashi , Yokota Jun , Esteller Manel
Published: April 2023

Supplementary Figure 1. KAT6B copy number and DNA methylation status in SCLC cell lines
Supplementary Tables S1-S10 from SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias
Authors: Vitali Caterina , Bassani Claudia , Chiodoni Claudia , Fellini Elisa , Guarnotta Carla , Miotti Silvia , Sangaletti Sabina , Fuligni Fabio , De Cecco Loris , Piccaluga Pier P. , Colombo Mario P. , Tripodo Claudio
Published: April 2023

Supplementary Tables S1-S10. Predicted STAT target genes according to motif gene sets from MSigDB collection (S1); Genes correlated with SOCS2 in AML/ALL/normal BM (S2); ARACNe predicted targets of IKZF1/Ikaros (neighbors) in lymphoid and myeloid BM precursors, AML and ALL (S3); ARACNe predicted putative targets of MEF2C (neighbors) in lymphoid and myeloid BM precursors, AML and ALL (S4); ARACNe predicted putative targets of IKZF1/Ikaros (neighbors) in mature B-lymphocytes and lymphomas (S5); ARACNe predicted putative targets of MEF2C (neighbors) in mature B-lymphocytes and lymphomas (S6); Differentially expressed Socs2-/- LKS vs. Wt LKS gene list with absolute FC>=2 and p<0.001 (S7); Enriched pathways in the dataset of Socs2-/- vs. Wt LKS at day 6 after 5-FU (S8); Curated gene sets associated to SOCS2 and shared by murine HSC under hematopioietic stress and human acute leukemias (S9); Oncogenic gene sets associated to SOCS2 and shared by murine HSC under hematopioietic stress and human acute leukemias (S10).
Supplemental Methods and References from Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites
Authors: Wang Qilong , Ren Yi , Mu Jingyao , Egilmez Nejat K. , Zhuang Xiaoyin , Deng Zhongbin , Zhang Lifeng , Yan Jun , Miller Donald , Zhang Huang-Ge
Published: April 2023

Supplemental Methods and References. Description of additional methods and procedures used in the study. Also includes Supplemental References.
Supplemental Figures S1-S9 from Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites
Authors: Wang Qilong , Ren Yi , Mu Jingyao , Egilmez Nejat K. , Zhuang Xiaoyin , Deng Zhongbin , Zhang Lifeng , Yan Jun , Miller Donald , Zhang Huang-Ge
Published: April 2023

Supplemental Figures S1-S9. Chemokine receptors expressed on PMA stimulated EL4 cells (S1); Uptake of GNVs membrane derived vesicles and stability of IGNVs (S2); Transmigration of GNVs and IGNVs (S3); Expression of integrins on EL4 cells and LFA-1 on IGNVs (S4); Purification of plasma membrane from leukocytes and chemokines in the culture medium of human SW620 cells (S5); Effects of IGNVs on cell proliferation in vitro and potential toxicity in vivo (S6); Therapeutic drug-loaded IGNVs and Characterization of DOX-NPTM and control liposomes from Avanti (S7); Biodistribution of DOX in 4T1 tumor tissues and therapeutic effect of IGNV-Cur on the inhibition of DSS-induced mouse colitis (S8); Determination of critical GNV miceller concentration (S9).
Supplementary Methods and References from Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death
Authors: Lee Eric A. , Angka Leonard , Rota Sarah-Grace , Hanlon Thomas , Mitchell Andrew , Hurren Rose , Wang Xiao Ming , Gronda Marcela , Boyaci Ezel , Bojko Barbara , Minden Mark , Sriskanthadevan Shrivani , Datti Alessandro , Wrana Jeffery L. , Edginton Andrea , Pawliszyn Janusz , Joseph Jamie W. , Quadrilatero Joe , Schimmer Aaron D. , Spagnuolo Paul A.
Published: April 2023

Supplementary Methods and References. Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplemental Figure Legends from Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding
Authors: Goldstein Michael , Kastan Michael B.
Published: April 2023

Supplemental Figure legends
Supplementary Figure Legends from Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death
Authors: Lee Eric A. , Angka Leonard , Rota Sarah-Grace , Hanlon Thomas , Mitchell Andrew , Hurren Rose , Wang Xiao Ming , Gronda Marcela , Boyaci Ezel , Bojko Barbara , Minden Mark , Sriskanthadevan Shrivani , Datti Alessandro , Wrana Jeffery L. , Edginton Andrea , Pawliszyn Janusz , Joseph Jamie W. , Quadrilatero Joe , Schimmer Aaron D. , Spagnuolo Paul A.
Published: April 2023

Legend for Supplementary Figures S1-S9.
Supplemental Figure 5 from Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding
Authors: Goldstein Michael , Kastan Michael B.
Published: April 2023

Figure S5. RAP80 suppresses excessive DSB processing
Supplementary Figure S3 from Early Prediction of Disease Progression in Small Cell Lung Cancer: Toward Model-Based Personalized Medicine in Oncology
Authors: Buil-Bruna Núria , Sahota Tarjinder , López-Picazo José-María , Moreno-Jiménez Marta , Martín-Algarra Salvador , Ribba Benjamin , Trocóniz Iñaki F.
Published: April 2023

Prediction accuracy at the individual level of RECIST model: Predicted probabilities of progression (sorted in ascending order) during treatment (SCAN 1 and SCAN 2, in green and orange) and at the first two follow-up CT scans (in blue and red) for patients in internal dataset (left) and external dataset (right) obtained from all data available (i.e. biomarker and CT scans outcome). Empty rhombuses represent patients that did not have disease progression in the CT scan and filled squares depict patients with observed disease progression at each CT scan. Dotted and solid lines depict the 25th and 75th quantiles corresponding to the individual posterior distribution.
Supplemental Figure 4 from Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding
Authors: Goldstein Michael , Kastan Michael B.
Published: April 2023

Figure S4. DSB repair in cycling cells depends on Brca1 and NBS1 but not RAP80
Supplemental Figure 3 from Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding
Authors: Goldstein Michael , Kastan Michael B.
Published: April 2023

Figure S3. MCF7 cells accumulate in G1 following serum starvation
Supplemental Figures 1 - 9, Table 1, Methods from CCL5-Mediated Th2 Immune Polarization Promotes Metastasis in Luminal Breast Cancer
Authors: Zhang Qianfei , Qin Jilong , Zhong Lin , Gong Lei , Zhang Bing , Zhang Yan , Gao Wei-Qiang
Published: April 2023

Figure S1. Analysis of IL4 expresion of CD4+ T cells and the number of CTC at different time points in MMTV-PyMT mice. Figure S2. Analysis of tumor-associated myeloid cells in MMTV-PyMT mice. Figure S3. Efficient in vivo depletion of CD4+ T cells following i. v. injection of anti-CD4 antibody (GK1.5) and analysis of tumor-associated myeloid cells in CCL5-/- PyMT mice after depletion of CD4+ T cells. Figure S4. Confirmation of the epithelial origin of MECs collected from the 3D-organoid co-culture. Figure S5. The expression of EMT-related genes in caner cells from CCL5+/+ PyMT and CCL5-/- PyMT mice. Figure S6. Protein level of CCL5 in different cell types of MMTV-PyMT mice. Figure S7. Quantification of Western Blotting data of Fig 5B and 5C. Figure S8. Efficient infection of lentivirus encoding Gfi1. Figure S9. Expression pattern of CCL5 receptors in CCL5+/+ PyMT mice. Figure S10. CCL5 and IL4 expression are not associated with the subtype of human luminal breast cancer. Percentage of IL4+CD4+ T cells in PBMC of luminal breast cancer patients. Table S1. Antibodies used in the paper.
Supplementary Materials and Methods from Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity
Authors: Mussai Francis , Egan Sharon , Hunter Stuart , Webber Hannah , Fisher Jonathan , Wheat Rachel , McConville Carmel , Sbirkov Yordan , Wheeler Kate , Bendle Gavin , Petrie Kevin , Anderson John , Chesler Louis , De Santo Carmela
Published: April 2023

Supplementary Materials and Methods. Supplementary Materials and Methods
Supplementary Methods from Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB
Authors: Zeng Zhiping , Sun Zhe , Huang Mingfeng , Zhang Weidong , Liu Jie , Chen Liqun , Chen Fan , Zhou Yuqi , Lin Jiacheng , Huang Fengyu , Xu Lin , Zhuang Zixing , Guo Shangjie , Alitongbieke Gulimiran , Xie Guobin , Xu Yang , Lin Bingzhen , Cao Xihua , Su Ying , Zhang Xiao-kun , Zhou Hu
Published: April 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplemental Table S1 from A Novel Cinnamon-Related Natural Product with Pim-1 Inhibitory Activity Inhibits Leukemia and Skin Cancer
Authors: Kim Jong-Eun , Son Joe Eun , Jeong Hyein , Kim Dong Joon , Seo Sang Gwon , Lee Eunjung , Lim Tae Gyu , Kim Jong Rhan , Kimbung Yengo Raymond , Chen Hanyong , Bode Ann M. , Lee Ki Won , Dong Zigang
Published: April 2023

Supplemental Table S1. Data collection and refinement statistics.
Supplementary Tables S1-S5 from Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State
Authors: Chien Chian-Shiu , Wang Mong-Lien , Chu Pen-Yuan , Chang Yuh-Lih , Liu Wei-Hsiu , Yu Cheng-Chia , Lan Yuan-Tzu , Huang Pin-I. , Lee Yi-Yen , Chen Yi-Wei , Lo Wen-Liang , Chiou Shih-Hwa
Published: April 2023

Supplementary Tables S1-S5. List of qPCR primer sequences (S1); List of proteins tested by antibodies (S2); Sponge and Antisense sequence of Let-7 constructions (S3); 3'UTR primer for ARID3B and HMGA2 (S4); Primers for Oct4 and Sox2 promoter constructions, ChIP and Q-ChIP (S5).