bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Early Life Stress on the Developing Basolateral Amygdala-Prefrontal Cortex Circuit: The Emerging Role of Local Inhibition and Perineuronal Nets
Authors: Guadagno Angela , Belliveau Claudia , Mechawar Naguib , Walker Claire-Dominique
Published: August 2021

The links between early life stress (ELS) and the emergence of psychopathology such as increased anxiety and depression are now well established, although the specific neurobiological and developmental mechanisms that translate ELS into poor health outcomes are still unclear. The consequences of ELS are complex because they depend on the form and severity of early stress, duration, and age of exposure as well as co-occurrence with other forms of physical or psychological trauma. The long term effects of ELS on the corticolimbic circuit underlying emotional and social behavior are particularly salient because ELS occurs during critical developmental periods in the establishment of this circuit, its local balance of inhibition:excitation and its connections with other neuronal pathways. Using examples drawn from the human and rodent literature, we review some of the consequences of ELS on the development of the corticolimbic circuit and how it might impact fear regulation in a sex- and hemispheric-dependent manner in both humans and rodents. We explore the effects of ELS on local inhibitory neurons and the formation of perineuronal nets (PNNs) that terminate critical periods of plasticity and promote the formation of stable local networks. Overall, the bulk of ELS studies report transient and/or long lasting alterations in both glutamatergic circuits and local inhibitory interneurons (INs) and their associated PNNs. Since the activity of INs plays a key role in the maturation of cortical regions and the formation of local field potentials, alterations in these INs triggered by ELS might critically participate in the development of psychiatric disorders in adulthood, including impaired fear extinction and anxiety behavior.
GAS6-AS1 Overexpression Increases GIMAP6 Expression and Inhibits Lung Adenocarcinoma Progression by Sponging miR-24-3p
Authors: Wang Yuanyong , Ma Minge , Li Chuan , Yang Yuling , Wang Maolong
Published: August 2021

GAS6 antisense RNA 1 (GAS6-AS1) is a long non-coding RNA involved in hepatocellular carcinoma and gastric cancer. However, the functional role of GAS6-AS1 in lung adenocarcinoma (LUAD) remains unclear. In the present study, qRT-PCR was used to measure the levels of GAS6-AS1, GIMAP6 and miR-24-3p expression in LUAD samples and cell lines. CCK-8 and colony formation assays were used to determine cell proliferation. Cell migration and invasion were evaluated using wound healing and transwell assays, respectively. The potential interactions between molecules were assessed using RNA immunoprecipitation and luciferase reporter assays. Western blot analysis was used to quantify protein expression. The anti-tumor effect of over-expressed GAS6-AS1 on LUAD was also examined in vivo in xenograft tumor experiments. The expression of GAS6-AS1 was notably downregulated in LUAD samples and cell lines and associated with a poor prognosis. GAS6-AS1 overexpression inhibited the migration and invasion of A549 and H1650 cells. Down-expressed GAS6-AS1 acted as a sponge for miR-24-3p and down-regulated the expression of its target, GTPase IMAP Family Member 6. These findings suggested that GAS6-AS1 might represent a potential diagnostic biomarker for LUAD.
RNA Sequence Profiling Reveals Unique Immune and Metabolic Features of Breast Cancer Brain Metastases
Authors: Xiao Limei , Zhou Jie , Liu Hongyi , Zhou Yuanyuan , Chen Weibin , Cui Wugeng , Zhao Yilin
Published: August 2021

There is an urgent need to improve our understanding of breast cancer brain metastases (BCBMs). Thus, we obtained transcriptome data of BCBMs, primary breast cancers (BCs), and extracranial metastases (BCEMs) from the Gene Expression Omnibus (GEO) database, including GSE43837, GSE14017, and GSE14018, for immune and metabolic analysis. Firstly, we performed immune and metabolic analysis on BCBMs and primary breast cancers of GSE43837 using RNA sequence. We identified significant immunosuppression and gene signatures associated with immune infiltration in BCBMs; the lower the expression of the signatures, the worse the prognosis of breast cancer patients in the Kaplan–Meier (KM) plotter [Breast cancer] database. We also identified increased oxidative phosphorylation (OXPHOS) utilization in BCBMs compared with BCs and gene signatures associated with increased OXPHOS utilization in BCBMs; the higher the expression of the signatures, the worse the prognosis of breast cancer patients in the KM plotter [Breast cancer] database, which can predict the prognosis of breast cancer patients better, as it can also predict the prognosis of patients with different breast cancer subtypes. In addition, we performed immune and metabolic analysis on BCBMs and extracranial metastases of GSE14017 and GSE14018 using RNA sequence. Compared with extracranial metastases, we identified more significant immunosuppression but no difference in OXPHOS utilization in BCBMs, which may be because OXPHOS was also involved in extracranial metastases. We have proven that OXPHOS was functionally significant in metastasis in vitro assays. Oligomycin, an OXPHOS inhibitor, substantially attenuated the migration and invasion potential of breast cancer cells. Our study provides new insights into the pathogenesis of BCBMs.

Significance

Our study reports the most comprehensive gene expression analysis of BCBMs, BCs and extracranial metastases to date. We identified immunosuppression and OXPHOS enrichment in BCBMs compared with BCs, which provide new insights into the pathogenesis of BCBMs and will facilitate the development of new therapeutic strategies for patients with BCBMs.
Virtual Physical Education During COVID-19: Exploring Future Directions for Equitable Online Learning Tools
Authors: D'Agostino Emily M. , Urtel Mark , Webster Collin A. , McMullen Jaimie , Culp Brian
Published: August 2021

Introduction: School closures prompted by the COVID-19 pandemic reduced opportunities for US youth to be physically active and disproportionately impacted health disparities in this population. Physical education provides the largest intervention to support the physical activity of school-aged youth, but teachers' opinions about how to maintain quality programming during virtual learning periods remain unexplored. Applying a diversity, equity and inclusion framework, this study explored physical education teachers' perceived significance of different design features for an online teaching tool to promote physical activity equity during school closures.

Methods: Previous literature and focus groups informed the development of a survey administered in summer/fall 2020. Survey participants (n = 60) were physical education teachers from 400 randomly selected US preschool-12th grade schools drawing from a national database. Participants rated the significance of four design features in relation to five key attributes of an online supplement to in-person physical education programs. One-way ANOVAs were used to assess differences in teachers' ratings by demographic characteristics.

Results: Between-group differences were found in teacher ratings of design features related to the usability, accessibility, equitability, and formal assessment capabilities of an online physical education tool. Differences were based on teacher gender, school level, and geographic location.

Conclusions: Future research to promote physical activity equity among preschool-12th grade youth should examine tailored virtual physical education learning tools that address what teachers perceive to be the most significant design features to support equitable physical education among diverse student groups.
Reducing Global Greenhouse Gas Emissions to Meet Climate Targets—A Comprehensive Quantification and Reasonable Options
Authors: Kern Christoph , Jess Andreas
Published: August 2021

A model is presented which covers the global greenhouse gas emissions (GHG emissions) and the energy consumption (fuels, electricity) in five sectors of end users, industry, transport, buildings, agriculture, and fugitive emissions. The electricity sector is also considered, but the associated GHG emissions are reallocated to the five end users. Different GHG reduction measures were calculated ranging from substitution of coal for electricity generation by renewables, electrification of road transport and buildings, restructuring of the sector industry to finally a 50% reduction of both food waste and meat consumption. To elucidate the consequences of global warming, future emission scenarios were also incorporated. One major conclusion is that the world can only reach the 2-degree climate target if electricity is only produced by renewables, and if transportation, buildings, and the industry are completely electrified by 2050. Compared to today, the electricity production by renewables will then rise by a factor of 11, and the total electricity demand by a factor of 2.4.
High-Voltage Polyanion Positive Electrode Materials
Authors: Yamada Atsuo
Published: August 2021

High-voltage generation (over 4 V versus Li+/Li) of polyanion-positive electrode materials is usually achieved by Ni3+/Ni2+, Co3+/Co2+, or V4+/V3+ redox couples, all of which, however, encounter cost and toxicity issues. In this short review, our recent efforts to utilize alternative abundant and less toxic Fe3+/Fe2+ and Cr4+/Cr3+ redox couples are summarized. Most successful examples are alluaudite Na2Fe2(SO4)3 (3.8 V versus sodium and hence 4.1 V versus lithium) and β1-Na3Al2(PO4)2F3-type Na3Cr2(PO4)2F3 (4.7 V versus sodium and hence 5.0 V versus lithium), where maximizing ΔG by edge-sharing Fe3+-Fe3+ Coulombic repulsion and the use of the 3d2/3d3 configuration of Cr4+/Cr3+ are essential for each case. Possible exploration of new high-voltage cathode materials is also discussed.
Optimization Study on Increasing Yield and Capacity of Fluid Catalytic Cracking (FCC) Units
Authors: Zhang Yuming , Li Ziming , Wang Zeyu , Jin Qibing
Published: August 2021

The fluidized catalytic cracking (FCC) unit is the primary production unit for gasoline and olefins in refineries. Improving product yield and processing capacity is closely related to the economic benefits of refineries. In this paper, we use the Aspen HYSYS software to model the mechanism of an 800 kt/a FCC unit in China. The simulation of the FCC unit based on the 21-lump models and the simulation results are in good agreement with the actual factory production data. Then we find out the optimization method to improve the product yield and processing capacity through the model research. The results of the study indicate the following optimization plans: when keeping the riser outlet temperature (ROT) in the range of 535~545 °C, it can increase the yield of gasoline and liquefied petroleum gas (LPG) by up to 5%; when keeping the riser outlet temperature (ROT) in the range of 510~520 °C, it can increase the yield of gasoline and diesel by up to 0.5%; the optimal ROT of control temperature should be 530 °C when ensuring the same gasoline yield and increasing processing capacity, it can increase the feed rate by 14.3% which in turn increases gasoline production. Through the above plans, the refinery can achieve the production goals of yield and capacity. Therefore, the refinery can get more profits.
A Framework for Assessing Import Costs of Medical Supplies and Results for a Tuberculosis Program in Karakalpakstan, Uzbekistan
Authors: Kohler Stefan , Sitali Norman , Paul Nicolas
Published: August 2021

Background
. Import of medical supplies is common, but limited knowledge about import costs and their structure introduces uncertainty to budget planning, cost management, and cost-effectiveness analysis of health programs. We aimed to estimate the import costs of a tuberculosis (TB) program in Uzbekistan, including the import costs of specific imported items.
Methods
. We developed a framework that applies costing and cost accounting to import costs. First, transport costs, customs-related costs, cargo weight, unit weights, and quantities ordered were gathered for a major shipment of medical supplies from the Médecins Sans Frontières (MSF) Procurement Unit in Amsterdam, the Netherlands, to a TB program in Karakalpakstan, Uzbekistan, in 2016. Second, air freight, land freight, and customs clearance cost totals were estimated. Third, total import costs were allocated to different cargos (standard, cool, and frozen), items (e.g., TB drugs), and units (e.g., one tablet) based on imported weight and quantity. Data sources were order invoices, waybills, the local MSF logistics department, and an MSF standard product list.
Results
. The shipment contained 1.8 million units of 85 medical items of standard, cool, and frozen cargo. The average import cost for the TB program was 9.0% of the shipment value. Import cost varied substantially between cargos (8.9–28% of the cargo value) and items (interquartile range 4.5–35% of the item value). The largest portion of the total import cost was caused by transport (82–99% of the cargo import cost) and allocated based on imported weight. Ten (14%) of the 69 items imported as standard cargo were associated with 85% of the standard cargo import cost. Standard cargo items could be grouped based on contributing to import costs predominantly through unit weight (e.g., fluids), imported quantity (e.g., tablets), or the combination of unit weight and imported quantity (e.g., items in powder form).
Conclusion
. The cost of importing medical supplies to a TB program in Karakalpakstan, Uzbekistan, was sizable, variable, and driven by a subset of imported items. The framework used to measure and account import costs can be adapted to other health programs.
The Silk, Versatile Material for Biological, Optical, and Electronic Fields: Review
Authors: Bibbo Luigi , Khan Karim , Tareen Ayesha Khan
Published: August 2021

Silk, seen as a material, is a fiber made from silkworm cocoons and spiders. They have standard structural components and hierarchical structures. Different manufacturing techniques allow obtaining silk in films, fibers, hydrogels, microspheres, and sponges. We can tune the properties through the structure of secondary proteins. The paper explores the application in biomedical, optics, and electronic fields by analyzing the technological trend.
The influence of Price, Innovation, and Brand Image on Purchase Decision
Authors: Pascaselnofra Amril Alwa
Published: August 2021

This study aims to determine how big the influence of price, innovation and brand image partially or jointly on purchasing decisions. The method of data collection was through questionnaires with a sample of 95 students from the Faculty of Economics, Universitas Negeri Padang, Department of Management. The method used is multiple regression analysis. The results of the correlation analysis test show that there is a significant relationship between price, innovation and brand image on purchasing decisions for LENOVO products. The results of the multiple linear regression analysis were obtained: (a) There is a negative and significant effect between price on purchasing decisions, as evidenced by the value of t-statistic < t-table (-2.627 < 1.986). (b) There is a positive and significant influence between innovation on purchasing decisions, as evidenced by the value of t-statistic > t-table (4.494 > 1.986). (c) There is a significant influence between brand image on purchasing decisions, as evidenced by the value of t-statistic > t-table (4.631 > 1.986). Then based on the joint hypothesis test (F test) it can be seen that the value of F-statistic > F-table (21.902 > 2.70). So the author concludes that price, innovation and brand image have a significant effect on purchasing decisions and the result of Determination (R2) the value is 0.419 this shows that the contribution of the influence of the variables studied in this study is 41.9% and the remaining 58.1% is influenced by the variables others outside of this study.
South Africa-Russia Trade Relations in the Mbeki-Putin Years, 1999-2008 -
Ideological Minimalism and Growing Commercial Flows
Authors: Ndzendze Bhaso
Published: August 2021

With both leaders focused on integration (or re-integration) with their respective regions, between South Africa and Russia under the coinciding presidencies of Thabo Mbeki and Vladimir Putin (1999 to 2008) distal ties would appear to have been a peripheral consideration, albeit one pursued with relative consistency. These years were un-ideological, having followed the collapse of the USSR but preceding the emergence of the intermittently ideological BRICS project. I use trade data from multiple sources to assess the two countries' economic relationship under these leaders. Upon noting the continued but slow growth in political interaction under the two leaders, the article documents the effects of political interaction on trade, which was encouraged by both leaders as they sought deeper south-south cooperation (SSC) and lessened dependency on the West (with which both countries were nevertheless growingly intertwined). Trade responded favourably on both sides after the 2006 mutual visits by the two presidents (as seen by 2007 trade volumes). Overall, under the Mbeki-Putin years, we observe Russian products forming a higher share of South African imports than the other way around, whilst growth in access to each other's markets saw mostly new access for South Africa (giving it a favourable surplus of over US$25-million, which grew to over US$2-billion under the Zuma years), thereby complicating our understanding of the relationship and the nature of the asymmetry which defines it.
Umbrales de disrupción: notas iniciales para una genealogía de las intervenciones críticas y didácticas sobre literatura y perspectivas sexogenéricas
Authors: Breganni Roberto
Published: August 2021

El presente artículo traza una genealogía inicial acerca de las intervenciones críticas y didácticas elaboradas desde los vínculos entre literatura y perspectivas sexogenéricas, en el marco del proceso de institucionalización de estos estudios en las carreras docentes de Letras de la universidad argentina. En este sentido, revisa intervenciones críticas de Nicolás Rosa, Jorge Panesi y Josefina Ludmer poniéndolas en diálogo con categorías, propuestas e hipótesis de trabajo presentes en sus programas de cátedra y seminarios de grado. Las consi-deraciones vertidas sugieren –a modo de esbozo preliminar– una posible mirada introductoria y conceptualiza-ciones construidas con el objeto de describir y explicar las reflexiones desarrolladas en el recorrido planteado.
Marketing transcultural en marcas sustentables como estrategia de empresas multinacionales
Authors:   , Chandler Bermúdez Paola Virginia
Published: August 2021

En la presente tesis se estudia el marketing transcultural en marcas sustentables como estrategia de empresas multinacionales, exponiendo las principales características de marcas que trascienden las barreras culturales en los diferentes mercados en los que opera. También, se describen los aspectos que debe poseer un producto o servicio para ser considerado sustentable, con el objetivo de estudiar las estrategias de marketing ecológicas aplicadas por grandes empresas. Al finalizar se analizan tres casos de estudio de empresas multinacionales: Nestle SA, Natura Cosméticos SA y Grupo Arcor SA, con el fin de sustentar las teorías desarrolladas a lo largo de la investigación. Las líneas de investigación y desarrollo futuras: Evaluar las estrategias de marcas sustentables en mercados internacionales post- pandemia y su compromiso social. Considerando la reducción de la inversión y maximización de recursos empresariales, impulsados por la caída del consumo de productos a nivel mundial.
DEVELOPMENT OF A METHODOLOGY FOR ASSESSING THE MANUFACTURABILITY OF INDUSTRIAL PRODUCTS IN THE CONDITIONS OF PILOT PRODUCTION
Authors: Malikova D.M.
Published: August 2021

The article is devoted to improving the reliability of a comprehensive quantitative assessment of the technological performance of the product design in the conditions of pilot production, taking into account the specific production and technological conditions of the enterprise by solving the problem of objective selection of technological performance indicators. To achieve this goal, the following tasks were solved: the indicators of the manufacturability of product designs, their quantitative assessment were studied; a mathematical model for the formation of design indicators of manufacturability was developed, the optimal set of indicators of manufacturability for a particular product was selected; a method for quantitative evaluation and expert selection of indicators of manufacturability by their weights was developed; an algorithm for determining the integral indicator of the product's manufacturability was developed; the developed algorithm for the integral evaluation of the product's manufacturability indicators was applied. The practical significance of the work lies in the approbation of the author's method of expert selection and the determination of the integral index of manufacturability. This indicator is one of the elements of improving the efficiency of the enterprise, especially in the conditions of pilot production. The method developed by the author makes it possible to more reliably assess the manufacturability of the product at the initial stages of design. A positive result was obtained by expert selection of indicators that take into account the design features and the technological level of the manufacturer. In addition, the proposed method made it possible to identify reserves for improving the manufacturability of the product design. The use of the author's methodology helps to reduce the time and costs associated with the development and production of a new product.
PROBLEMS OF LEGISLATIVE REGULATION OF THE MURDER OF A NEWBORN CHILD BY A MOTHER (ARTICLE 106 OF THE CRIMINAL CODE OF THE RUSSIAN FEDERATION)
Authors: Gafurova E.R.
Published: August 2021

This article examines the features of the Russian criminal law norm that provides for liability for the murder of a newborn child by a mother. We analyzed the data of the Judicial Department on the statistics of convicts for 2016 and 2019 under Article 106 of the Criminal Code of the Russian Federation in relation to the indicators of other privileged elements of murder, indicating the latency of this type of crime. The article also examines some features of the legislative structure of Article 106 of the Criminal Code of the Russian Federation, accompanied by examples of judicial practice. The article examines the criminal law norms providing for responsibility for infanticide, the legislation of Italy, Austria, Switzerland, Holland and Denmark, and highlights the distinctive features of Article 106 of the Russian criminal legislation. The article presents proposals for possible improvement of the norms of the Criminal Code of the Russian Federation on responsibility for the murder of a newborn child by a mother, confirmed by the indicators of a sociological study.
SIGNIFICANCE OF THE ADVERSARIAL USE OF MATERIAL EVIDENCE IN CRIMINAL PROCEEDINGS
Authors: Muratov K.D.
Published: August 2021

The idea of adversariality in criminal proceedings, carried away by its simplicity and originality in the context of public legal relations, after a certain period of time had passed the Criminal Procedure Code of the Russian Federation, gradually began to be reasonably questioned. The study of procedural procedures, the recognition of objects and documents as material evidence, as well as the subjects of the collection and presentation of material evidence, allow a closer look at the legal relationship and powers of the parties in criminal proceedings in the field of their implementation both in pre-trial and in court proceedings. Investigative and judicial processes as historically established forms of criminal procedure should be adversarial. The author examines the importance of the adversarial nature of the parties in the formation of material evidence in criminal cases and their assessment by the parties when substantiating the conclusions in the case, shows their theoretical and legal significance, procedural and legal, preventive and prophylactic and informational and evidentiary value.
SOCIAL AND ECONOMIC CONDITIONALITY OF CRIMINAL LEGAL PROTECTION OF LAND RELATIONS
Authors: Khaperskaya K.S.
Published: August 2021

The problem of rational (ecologically, socially and economically sound) use and protection of land is always relevant. States face the task of preserving land as the planet's most valuable resource. The specified component of the natural environment provides natural regulation of many processes occurring in the ecological system of the Earth, which predetermines the need for maximum preservation of its natural properties. The social danger of such a crime as damage to land is expressed in causing damage to the national property of Russia, the main means of production and the basis of the functioning of all sectors of the economy - land. In addition, spoilage of land in the general structure of environmental crime is a deterrent to the growth of the quality and standard of living of the population and the development of Russian production, regional development. In this regard, it seems relevant to study the socio-economic component of criminal law protection of land relations, land crimes, their analysis in order to timely respond to crimes committed in this area.
LEGAL-THEORETICAL ANALYSIS OF FREEDOM OF SPEECH IN THE UNIVERSAL AND REGIONAL DIMENSION: THE EDGE OF REASON
Authors: Bezborodov Yu.S.
Published: August 2021

In the theory of law, freedom of speech, which has a long history of formation, continuing even now - with the crystallization of this freedom by international institutions, remains the most important and necessary element of the functioning of civil society and the building of the rule of law. In the legal plane, being initially enshrined at the international level - universal and regional - this freedom faces serious obstacles to its realization and protection at the national level, where it collides with other rights and freedoms, including freedom of religion, as well as with the interests of society and the state which are often difficult to establish. One of the fundamental issues related to the realization of freedom of speech is the question of the absoluteness and limitations of this freedom. Restrictions on freedom of speech, established normatively and developed by practice at the universal and European regional international legal level, are associated with considerations of morality, social interests and values, necessity and security. These approaches developed at different levels of regulation are mutually consistent and complement each other, building a paradigm that is much needed by general international law in a uniform understanding of human rights and freedoms. Despite the established restrictions, in practice, contradictions and misunderstandings continue to arise related to the implementation of freedom of speech at the national level. This work attempts to correlate freedom of speech with restrictions on this freedom by states bound by security interests, morality and ethics. The article proposes an effective way to solve the problem of limiting freedom of speech and delimiting it from other freedoms: increasing the responsibility of states for violating human rights and freedoms by changing its form, and strengthening the jurisdiction of already existing international bodies for the protection of human rights, especially conventions.
A new region-of-interest (ROI) detection method using the chan-vese algorithm for lung nodule classification
Authors: ÇINAR Ali , TOPUZ Bengisu , ERGİN Semih
Published: August 2021

Suspicious regions in chest x-rays are detected automatically, and these regions are classified into three types, including “malignant nodule”, “benign nodule”, and “no nodule” in this study. Firstly, the areas except the lung tissues are removed in each chest x-ray using the thresholding method. Then, Poisson noise was removed from the images by applying the gradient filter. Ribs may overlap onto nodules. Since this circumstance will make the detection of a nodule difficult, it is necessary to distinguish and suppress the ribs. The location of the rib bones is determined by a template matching method, and then the corresponding bones are suppressed by applying the Gabor filter. After this stage, suspicious tissues in the chest x-rays are specified using the Chan-Vese active contour without edges. Then, some features are extracted from these suspicious regions. Six different features are extracted: Statistical, Histogram of Oriented Gradients (HOG)-based, Local Binary Pattern (LBP)-based, Geometrical, Gray Level Co-Occurrence Matrix (GLCM) Texture-based and Dense Scale Invariant Feature Transform (DSIFT)-based. Then, the classification stage is achieved using these features. The best classification result is obtained using statistical, LBP-based, and HOG-Based features. The classification results are evaluated with sensitivity, accuracy, and specificity analyses. K-Nearest Neighbour (KNN), Decision Tree (DT), Random Forest (RF), Logistic Linear Classifier (LLC), Support Vector Machines (SVM), Fisher’s Linear Discriminant Analysis (FLDA), and Naive Bayes (NB) methods are used for the classification purpose separately. The random forest classifier gives the best results with 57% sensitivity, 66% accuracy, 81% specificity values.
MegaStitch: Robust Large Scale Image Stitching
Authors: Zarei Ariyan , Gonzalez Emmanuel , Merchant Nirav , Pauli Duke , Lyons Eric , Barnard Kobus
Published: August 2021

Method details are available in the manuscript.
A Review on Coexistence Issues of Broadband Millimeter-Wave Communications
Authors: Tai Ching-Lun , Wu Derek
Published: August 2021

With higher frequencies and broader spectrum than conventional frequency bands, the millimeter-wave (mmWave) band is suitable for next-generation wireless networks featuring short-distance high-rate communications. As a newcomer, mmWaves are expected to have the backward compatibility with existing services and collaborate with other technologies in order to enhance system performances. Therefore, the coexistence issues become an essential topic for next-generation wireless communications. In this paper, we systematically review the coexistence issues of broadband mmWave communications and their corresponding solutions proposed in the literature, helping shed light on the insights of the mmWave design. Particularly, the works surveyed in this paper can be classiﬁed into four categories: coexistence with microwave communications, coexistence with ﬁxed services, coexistence with non-orthogonal multiple access (NOMA), and other coexistence issues. Results of numerical evaluations inspired by the literature are presented for a deeper analysis. We also point out some challenges and future directions for each category as a roadmap to further investigate the coexistence issues of broadband mmWave communications.
Alimentação e Prática de Atividade Física, no Tratamento da Síndrome dos Ovários Policísticos: Revisão Integrativa
Authors: Faria Leidiane dos Anjos , Silva Wanessa Souza , Passos Sandra Godoi de
Published: August 2021

Objetivo: investigar a importância da alimentação saudável associada à prática de atividades física, no auxílio ao tratamento contra a síndrome dos ovários policísticos (SOP). Método: optou-se por um estudo de revisão integrativa nas bases de dados Scielo, Lilacs e Bireme. Resultados: é uma patologia que requer atenção, pela delicadeza a que é imposta, por acometer os ovários da mulher, porém existem meios de minimizar os sintomas e prevenir complicações. Conclusão: a prática de exercícios físicos combinados a uma alimentação balanceada, são essenciais no tratamento. Ainda melhora no metabolismo corporal, alterações hormonais e cardiorrespiratórios, dentre outras vantagens. Ter consciência da doença e fazer o tratamento corretamente, são fatores que contam positivamente, evitando assim, possíveis complicações futuras.
Monitoramento COVID-19: Avaliação De Um Município Localizado no Estado do Paraná
Authors: Santos Wagner Galisa dos , Fernandes Lillian Caroline , Bessa Ana Paula Rodrigues dos Santos , Silva Carla Luiza da , Budk Monique Costa , Schamne Marissa Giovanna
Published: August 2021

Objetivo: descrever as ações de monitoramento e avaliar o impacto desta atividade durante a situação da pandemia. Método: trata-se de uma pesquisa epidemiológica observacional do tipo descritiva, buscando compreender o impacto, das estratégias de monitoramento no acompanhamento dos casos suspeitos e/ou confirmados pela Vigilância Epidemiológica. Resultados: houve o monitoramento de usuários com suspeita ou confirmação de síndrome gripal. Evidenciou-se a importância do monitoramento para o munícipio, pois após a busca ativa e identificação dos sintomas, possibilitou o cuidado centrado nas diretrizes assistências do SUS. Conclusão: o monitoramento se mostrou eficaz, uma vez que a maior parte dos usuários se recuperaram da infecção e tiveram seus casos acompanhados.
BATMIŞ HİDROLİK SIÇRAMADA GERİ DÖNÜŞ BÖLGESİ UZUNLUĞUNUN YAPAY ZEKÂ YÖNTEMLERİYLE TAHMİNİ
Authors: GÜMÜŞ Veysel , YOLUK İbrahim Mahmut , ŞİMŞEK Oğuz , SOYDAN Göksu
Published: August 2021

Bu çalışmada, içerisinde kayar kapak bulunan bir laboratuvar kanalının mansabında meydana gelmiş batmış hidrolik sıçramanın geri dönüş bölgesinin uzunluğu deneysel olarak belirlenmiştir. Deneysel olarak kapak açıklığı, mansap su yüksekliği, froude sayıları kullanılarak farklı yapay zekâ yöntemleri ve Çoklu Doğrusal Regresyon (ÇDR) yöntemi ile batmış hidrolik sıçramada geri dönüş bölgesinin uzunluğu tahmin edilmiştir. Yapay zekâ yöntemleri olarak Yapay Sinir Ağları (YSA), Uyarlamalı Ağ Tabanlı Bulanık Mantık Çıkarım Sistemi (ANFIS) ve Genexpresyon Programlama (GEP) yöntemleri tercih edilmiştir. Yöntemlerin geri dönüş bölgesinin uzunluğunu tahmin etmedeki başarı performanslarını belirlemek için belirlilik katsayısı (R2), Ortalama Karesel Hata (OKH) ve Ortalama Mutlak Göreceli Hata (OMGH) parametreleri kullanılmıştır. Çalışma sonucunda, kapak açıklığı, mansap su yüksekliği ve froude sayısını girdi parametresi olarak kullanan YSA ve ANFIS yöntemlerinin sıçrama geri dönüş bölgesinin uzunluğunu belirlemede oldukça başarılı olduğu belirlenmiştir.
GRAFİT KATKILI SİKLO-OLEFİN KOPOLİMER (COC) KOMPOZİTLERİN TRİBOLOJİK ÖZELLİKLERİNİN İNCELENMESİ
Authors: KILINÇ İbrahim , YETGİN Salih Hakan
Published: August 2021

Bu çalışmada, ağırlıkça %5, %15, %30, %45, %60 ve %75 oranlarında grafit katkılı siklo-olefin kopolimer (COC) kompozitleri ekstrüzyon ve basınçlı kalıplama yöntemleri ile üretilmiştir. Sürtünme ve aşınma deneyleri, disk üzerinde pim sistemi (pim-disk) ile kuru ortam şartlarında, 20 N, 30 N ve 40 N yük ve 0.5 m/s, 1.0 m/s ve 1.5 m/s kayma hızında gerçekleştirilmiştir. COC polimeri ve grafit katkılı COC kompozitlerin artan kayma hızı ve yüke bağlı olarak sürtünme katsayısı azalmış aşınma oranı ise artmıştır. En düşük sürtünme katsayısı ve aşınma oranı %75 grafit katkılı COC kompozitinde elde edilmiştir. COC polimerine eklenen %75 oranındaki grafit katkısı ile sürtünme katsayısı %87.7 oranında, aşınma oranı ise %498.79 oranında azalmıştır.
KUMLU ZEMİNDE TEŞKİL EDİLEN KAZIKLI RADYE TEMEL SİSTEMLERİNİN DİNAMİK DAVRANIŞININ İNCELENMESİ: KKTC-LEFKE ÖRNEĞİ
Authors: ÇİMEN Ömür , OSMANOĞLU Uğur
Published: August 2021

Bu çalışmada, Kuzey Kıbrıs Türk Cumhuriyeti’nin Lefke ilçesinde yer alan kumlu bir zeminde oturma probleminden dolayı tasarlanan kazıklı radye temel sistemlerinin dinamik davranışları incelenmiştir.
Tasarım ve analizler için, öncelikle Etabs programında 19 katlı 60,5 m yüksekliğinde betonarme bina modellenmiştir. Kumlu zeminde radye temel teşkil edilmesi halinde üstyapıdan temele aktarılan maksimum eksenel yükün oturma probleminden dolayı güvenilir bir şekilde taşınmadığı hesapla gösterilmiş ve ardından kazıklı radye temel tasarımlarına gidilmiştir. Kazık tasarımlarında sistemin değişken parametreleri olarak kazık sayısı, kazık çapı ve kazık uzunluğu değerleri kullanılmıştır. Bu bağlamda, 18 farklı kazıklı radye temel tasarımı yapılmış ve bu tasarımların her biri Plaxis 2D programında modellenerek dinamik analizleri gerçekleştirilmiştir. Dinamik analizler sonucunda, temel sistemlerinde oluşan oturma ve yanal deformasyon değerleri incelenmiştir. Bu çalışmanın sonucu olarak, kazık sayısı, kazık çapı ve kazık uzunluğunun, kumlu zeminde tasarlanan kazıklı radye temel sistemlerinde dinamik etki altında oluşan deformasyonları nasıl etkilediği saptanmıştır.
Upaya Orang Tua Menumbuhkan Minat Baca Anak pada Alkitab
Authors: Hulu Libertina , Lase Delipiter , Ndraha Amurisi
Published: August 2021

Mengajarkan Alkitab secara kreatif kepada anak-anak sejak usia dini akan menolong mereka untuk memahami hal yang utama tentang kehidupan, menguatkan mereka menghadapi dan mengatasi tantangan serta mengajari anak untuk menjalani kehidupan yang tidak didominasi oleh dosa. Karena itu, orang tua berkewajiban untuk menumbuhkan minat baca anak terhadap Alkitab sejak dini, karena orang tua adalah orang yang terdekat pertama bagi anak. Artikel ini bertujuan untuk menyelidiki bagaimana minat baca anak terhadap Alkitab, mencari tahu faktor penyebab serta pada bagian akhir pembahasan, penulis memaparkan upaya dan strategi orang tua menumbuhkan minat baca anak terhadap Alkitab. Penelitian dikembangkan dengan menggunakan metode kualitatif. Sumber data dan informan berjumlah 14 orang terdiri dari orang tua dan anak usia 6-12 tahun; ditentukan dengan teknik purposive sampling. Data diambil berdasarkan observasi dan wawancara, serta data yang telah diperoleh dianalisis dengan teknik analisis tematik. Temuan penelitian menujukkan bahwa minat baca anak terhadap Alkitab masih sangat rendah; setiap sepuluh orang anak usia sekolah dasar terdapat tidak lebih dari tiga orang yang gemar (memiliki minat) membaca Alkitab. Penyebab rendahnya minat baca anak terhadap Alkitab diklasifikasi ke dalam empat faktor, yakni lingkungan keluarga, sarana dan fasilitas bacaan, perkembangan teknologi, literasi baca tulis dan pola asuh orang tua. Pada bagian akhir artikel, penulis menyarankan beberapa upaya yang dapat diterapkan oleh orang tua untuk menumbuhkan minat baca anak terhadap Alkitab, di antaranya menyediakan bahan bacaan Alkitab yang beragam, mengatur waktu ibadah dalam keluarga, membatasi kegiatan anak untuk menonton dan bermain secara berlebihan, serta menjadikan waktu renungan sebagai kebiasaan.
Pengaruh Pemahaman Kewirausahaan, Pelatihan Kewirausahaan, dan Minat Berwirausaha dalam Upaya Peningkatan Produktivitas Usaha
Authors: Sukirman Sukirman , Afifi Z.
Published: August 2021

Penelitian yang telah diseminarkan pada Duconomics Sci-meet 2021 ini bertujuan untuk menganalisis pengaruh pemahaman kewirausahaan, pelatihan kewirausahaan, dan minat berwirausaha dalam meningkatkan produktivitas usaha. Populasi dalam penelitian ini adalah mahasiswa peserta program pengembangan kewirausahaan Universitas Muria Kudus sejumlah 264 mahasiswa. Penentuan jumlah sampel menggunakan rumus Slovin terdiri dari 136 mahasiswa, dengan teknik sampling menggunakan proposional random sampling. Teknik analisis data menggunakan structural equation modeling (SEM) dengan software AMOS 21. Hasil penelitian menunjukkan bahwa pemahaman kewirausahaan dan pelatihan kewirausahaan berpengaruh positif dan signifikan terhadap minat berwirausaha, pemahaman kewirausahaan dan pelatihan kewirausahaan berpengaruh positif dan signifikan terhadap produktivitas usaha dan minat berwirausaha berpengaruh positif dan signifikan terhadap produktivitas usaha. Minat berwirausaha mempunyai pengaruh yang positif dan signifikan dalam memediasi pemahaman kewirausahaan terhadap produktivitas usaha. Minat berwirausaha mempunyai pengaruh yang positif untuk menjadi intervening dalam memediasi pelatihan kewirausahaan terhadap produktivitas usaha.
Understanding the Role of Health Workers in the LF Elimination Program in Kenya: Challenges Faced and Suggestions for Improved Program Performance
Authors: Kimani Bridget W , Kibe Lydiah Wanjiku , Okoyo Collins , Omondi Wyckliff P , Sultani Hadley Matendechero , Njomo Doris Wairimu
Published: August 2021

The Kenyan Ministry of Health and its partners through the Division of Vector-Borne and Neglected Tropical Diseases, is in charge of the Lymphatic Filariasis Mass Drug Administration programme. This is implemented through the national, county, and sub-county neglected tropical diseases coordinators. The current study sought to understand the roles, challenges faced and suggestions of how program performance can be improved by the community health extension workers, county and sub-county neglected tropical diseases coordinators. Two wards of the Kaloleni sub-county; Kilifi County were purposively selected. In 2015, Kaloleni and Kayafungo wards had a treatment coverage of 58% and 54% respectively; 62% and 39% respectively in 2016, all below the recommended minimum treatment coverage of 65%.  Qualitative data was collected through sixteen in-depth interviews with community health extension workers and two semi-structured interviews with the county and sub-county neglected tropical diseases coordinators. Data were analysed by QSR NVIVO version 10 according to identified themes. The study results show the various roles in planning and implementation of the program include; supply chain management; health information education communication and records management; health workforce training and management, leadership and governance, and service delivery. Challenges faced included insufficiency of drugs supplied and information education communication materials, the inadequacy of community drug distributors selected and trained, poor facilitation for training and supervision of community drug distributors, limited duration of the mass drug administration, and delayed reporting due to poor network coverage. The results of this study show that the community health extension workers, county and sub-county neglected tropical diseases coordinators are not fully involved in program leadership and governance, a role that is taken up at the national level. They should be involved in all the stages of the mass drug administration program to create ownership to improve the program performance
Suojeluskuntaperinnetyön organisaatiot ja ulottuvuudet 1944–2021
Authors: Kleemola Olli
Published: August 2021

Suojeluskunnat lakkautettiin syksyllä 1944 Neuvostoliiton vaatimuksesta ja välirauhansopimuksen nojalla. Etenkin suojeluskunnissa toimineet kokivat lakkautuspäätöksen epäoikeudenmukaiseksi, ja syntyi halu ylläpitää suojeluskunta-, lotta- ja suojeluskuntiin kiinteästi liittyneen sotilaspoikajärjestön perinnettä. Tässä tutkimuksessa tarkastellaan suojeluskuntien lakkauttamisen jälkeen tehtyä, suojeluskuntaperheen eri jäseniin liittyvää perinnetyötä eli järjestöihin liittyvän kulttuuriperinnön säilyttämiseen tähtääviä toimenpiteitä.

Tutkimuksen tavoitteena on tarkastella yhtäältä perinnekentän muotoutumista eli perinnetyön organisoitumista eri järjestöihin. Toisaalta tarkastelun kohteena ovat perinnetyön sisällöt eli se, mitä toimia perinnekentällä on tehty kulttuuriperinnön siirtämiseksi. Tutkimuksen kolmantena ulottuvuutena on perinnetyön aineellinen ulottuvuus, eli minkälaista esineistöä tai aineistoa perinnekentän toimijat ovat tuottaneet perinnekentän tarpeisiin. Näiden kolmen ulottuvuuden avulla pyritään luomaan kokonaiskuva perinnetyön kehityksestä sodanjälkeisistä ajoista nykypäivään. Tutkimuksen aikahorisontti ulottuu vuodesta 1944 eli suojeluskunta- ja lottajärjestön lakkauttamisesta nykypäivään.Tutkimus avaa merkittäviä näkökulmia kansallisen maanpuolustushistoriallisen yhdistyskentän muotoutumiseen ja maanpuolustushistoriallisen kiinnostuksen ja perinnetyön merkityksen kasvuun viime vuosikymmeninä sekä yleensä perinnetyön merkitykseen suomalaisessa yhteiskunnassa.
Futbol Hakemlerinin Algıladıkları Stres Kaynakları ve Yaşam Doyumlarının İncelenmesi
Authors: ŞİRİN Tayfun
Published: August 2021

Bu çalışmanın amacı Futbol hakemlerinin futbol maçları sırasında algıladıkları stres kaynaklarını ve yaşam doyumlarını demografik özelliklere göre incelemektir. Bu amaç doğrultusunda katılımcılara hazırlanan demografik sorular ile hakemlerin stres kaynaklarını belirleyebilmek için Koca ve Yıldız (2018) tarafından geliştirilen “Futbol Hakemlerini Strese İten Faktörler Ölçeği ile yaşam doyumlarını belirlemek için Diener ve ark. (1985) tarafından geliştirilen Köker (1991) tarafından Türkçeye uyarlanan Yaşam Doyumu ölçeği kullanılmıştır. Araştırmanın örneklemini 90 Akdeniz bölgesi futbol hakemi oluşturmaktadır. Verilerin analizinde tanımlayıcı istatistik yöntemleri, t-testi ve anova analizi kullanılmıştır.
Araştırma sonucunda futbol hakemlerinin medeni durum ve klasman değişkeni ile stres kaynakları arasında anlamlı farlılık bulunur iken (p<.05) bu iki değişken ile yaşam doyumları ile arasında herhangi bir farklılığa rastlanmadı (p>.05). Araştırmanın diğer bir sonucu olarak hakemlikten önce futbol oynama değişkeni ve eğitim durumları ile stres kaynakları ve yaşam doyumları arasında herhangi bir farklılık görülmedi (p>.05). Hakemlerin yaş ve eğitim durumları değişkenleri ile stres kaynakları algılamaları arasında farklılık bulundu (p<.05). Ancak yaşam doyumları ile herhangi bir farklılığa rastlanamadı.
Araştırma sonucunda futbol hakemlerinin algıladıkları stres faktörlerinin düşük düzeyde yaşam doyumlarının ise yüksek düzeyde olduğu tespit edilmiştir. Sonuçlar incelendiğinde bekar olan hakemlerin evli olan hakemlere göre stres kaynakları ortalamalarının yüksek olduğu bulundu. Aynı zamanda yaş aralığı 16-21 olan ve aday hakem klasmanında görev yapan hakemlerin stres kaynaklarının Yüksek olduğu sonucuna ulaşıldı. Gelir seviyesi düşük olan hakemlerin stres kaynakları ortalamaları yüksek ve yaşam doyumları düşük bulundu
A Lattice Boltzmann Scheme for Polarized Radiative Transfer in Planetary Atmospheres
Authors: Liu Xiaochuan , Zhu Keyong , Shao Jiang , Huang Yong
Published: August 2021

Quantitative calculation of reflected polarized light from planets is of great significance to interpret the polarimetric observations of planetary atmospheres. In this work, we propose a lattice Boltzmann (LB) scheme for polarized radiative transfer in planetary atmospheres. The LB scheme obtains the Stokes vector through the vector LB equation performing simple collision and streaming processes. The vector radiative transfer equation is rigorously derived from the vector LB equation via the Maxwell iteration technique. Polarized radiative transfer of a single point on the planetary surface with Rayleigh and Mie scattering atmospheres are first accurately solved by our LB scheme. Afterward, we systematically investigate the disk-integrated polarization of finite and semi-infinite, conservative and nonconservative Rayleigh scattering planetary atmospheres. The disk-integrated phase curves of the Stokes parameters and degree of polarization and spherical and geometric albedos are produced, which are in good agreement with the benchmark results for different cases. The numerical results indicate that our LB scheme is efficient and accurate for polarized radiative transfer in planetary atmospheres. Our LB scheme is expected to provide a competitive numerical tool to interpret the polarimetric observations of planetary atmospheres.