bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemanfaatan Limbah Bonggol Jagung Sebagai Media Tanam Jamur di Masyarakat Desa Kawo Kecaman Pujut Kabupaten Lombok Tengah
Authors: Yeyen Riska Pramita  , Munawir Sazali  , Heri Murtawan
Published: January 2025

The utilization of corn stalk waste for mushroom cultivation is one of the efforts to reduce agricultural waste, namely from corn commodities. In order for the cultivation of merang mushrooms to obtain maximum results, it is necessary to optimize it. Optimization carried out in the utilization of corn stalks is by providing assistance, and training through counseling, practice, and demonstrations including material preparation, medium formulation, making mushroom growth medium, and mushroom maintenance management. The purpose of this service is to increase community understanding of the utilization of corn stalk waste as a mushroom growing medium and as an alternative business for the people of Gilik Hamlet, Kawo Village, Pujut District, Central Lombok Regency in increasing their daily income. The method used in the implementation method in this community service activity begins with a location survey, information dissemination, training (hands-on practice), and mentoring. This community service activity was carried out in Gilik Hamlet, Kawo Village, Pujut District, Central Lombok Regency on Sunday, April 07, 2024 at 15:00 WITA-complete. The procedure for making mushrooms starts with preparing the cultivation site, making a mixture, placing and leveling the corn stalks in the cultivation site, then, watering it evenly with water and covering it with a tarpaulin to keep it moist and warm. The initial yield of harvesting corncob mushrooms ranges from four to five kilos in one harvest. These mushrooms can be harvested every afternoon. The mushroom marketing process is carried out online through WhatsApp and Facebook media. The marketing price of this mushroom ranges from 35-40 per kg.
Pelatihan Pembuatan Ecoprint Menggunakan Tekhnik Pounding Di Tolotongga, Kota Bima Nusa Tenggara Barat
Authors: Ditiyyah Hafidzah  , M. Harja Efendi  , R. Didi Kuswara  , Anis Syakiratur Rizki
Published: January 2025

Ecoprint is a natural printing and coloring technique that is very easy to make and easy to obtain because this technique is environmentally friendly and does not harm the environment. This technique can use plants as basic materials in producing a variety of unique and interesting motifs. The purpose of this service activity is to provide artistic skills and skills in processing various types of plants in the Tolotongga environment into the main material for printing and coloring motifs on fabrics. The method used in this ecoprinting activity is to use training methods and direct practice on several communities in the Tolotongga Neighborhood, Bima City, West Nusa Tenggara. This activity starts from the stage of preparing tools and materials that will be used in ecoprinting then conducting training to the final result stage. The results of this training in the form of various motifs from the pounding technique applied to white t-shirts can be used.
Pemanfaatan Sampah Plastik Dalam Pembuatan Ecobrick Pada Kegiatan Pengabdian Masyarakat di SDN 46 Cakra Negara, Kota Mataram
Authors: Ega Dwi Putri Rahayu  , Ali Harris  , Nuzuly Ilmia Cerminand
Published: January 2025

Plastik waste in Indonesia has become a serious problem that everyone must pay attention to. Very high use of plastik can affect environmental problems, human health and the economy. The high use of plastik and lack of adequate waste management infrastructure has led to large accumulations of plastik waste in this country. Plastik waste that we throw away carelessly can pollute rivers, oceans, land and threaten biodiversity, and can even cause natural disasters such as floods. The aim of making Ecobricks is to be a solution in reducing the accumulation of plastik waste. Ecobricks can be used in making home furniture such as. Chairs, tables, walls, and can be used as environmentally friendly buildings. Community service method with SDN 46 Cakra Negara students in dealing with the problem of plastik waste with direct practice in making Ecobricks. Results: In community service, the author uses used household plastik waste and food packaging around the author's house. Conclusion: Community service involving class V girls at SDN 46 Cakra Negara has run smoothly according to the processes and methods used so that class V girls are very enthusiastic in carrying out activities regarding waste management by utilizing household waste. Ecobricks are one option in dealing with environmental problems caused by plastik waste.
Pendampingan Masyarakat Desa Pringgasela Timur dalam Proses Pembuatan Bibit Hortikultura
Authors: Moh. Fauzan Azima  , M. Harja Efendi  , Heri Murtawan  , Leny Fitriah  , Husnul Budiatman Dani
Published: January 2025

East Pringgasela Village is located in Pringgasela Sub-district, East Lombok Regency, NTB. About 27.5 hectares of land in this village is agricultural. Therefore, the potential to develop horticultural crops is huge. Horticulture is the cultivation of fruits, vegetables and ornamental plants. The purpose of this mentoring activity is to empower the community to be more independent and able to develop their own agricultural businesses. The implementation method used is the method of socialization and direct practice. The results of mentoring activities for the eastern Pringgasela village community in the process of making horticultural seeds have succeeded in increasing community interest and have succeeded in empowering the community as evidenced by the presence of 5 people who will try to make nurseries independently. So this mentoring activity is strongly supported by the surrounding community as evidenced by the great enthusiasm of the community in participating in this activity.
Penerapan Reduced Impact Logging Dalam Perencanaan Pemanenan Hutan Di Hutan Hujan Tropis Indonesia
Authors: Muamar Kadafin  , Alfian Pujian Hadi  , Imam Syaukani  , Akbar Al Imam
Published: January 2025

The Indonesian forests occupied the third area in the world with tropical forests as well as donations of rainforests in Kalimantan and Papua. Currently, wood is still the prima in a forestry sector so that the highest income generated by the forest comes to wood shoppers. The destructive logging process can cause damage to the environment. Forest harvesting planning needs to be carried out as an effort to reduce the impact of soil or the upright damage caused by logging. In addition, the use of Reduced Impact Logging (RIL) techniques in forest harvesting are other solutions to reduce the impact of the damage caused by for harvesting activities. This paper is made with the aim of knowing the influence of the use of RIL engineering on the impact of damage caused by forest harvesting activities in tropical rainforests in Indonesia. Data collection is conducted using the literature study method, while the data analysis techniques used are the analysis method for obtaining valid inference and can re-check the context. The results of the literature study indicate that the forest harvesting planning system used in the Indonesian Tropical Rainforests is composed of strategik planning, operational planning, and task planning. Forest harvesting techniques used in the Indonesian Tropical Rainforests consist of Conventional Logging (CL) and Reduced Impact Logging (RIL). The application of RIL techniques has a positive impact on the environment, as it can reduce the upright rate of damage, reducing the level of carbon mass reduction caused by forest harvesting, as well as from the aspects of RIL-eating financial analysis of wood-eating analysis, better than conventional wooden wasteers if the wooden-eating waste is calculated.
Analisis Karakteristik Morfologi Famili Poaceae (Gramineae) di Kawasan Lembuak Kebon, Kecamatan Narmada Kabupaten Lombok Barat
Authors: Khairunnisa Al Izzati  , M. Harja Efendi  , Nining Purwati
Published: January 2025

The purpose of this mini research is to find out the various types or species and morphology of the family Poaceae (Gramineae) ranging from grasses to bambo and corn. The method used in this mini research is random sampling technique, where random sampling technique is a random sampling of the family Paceae (Gramineae) found in the selected area. Mini research was carried out by exploring the location of the plantation and collecting information about the existence of plant species of the Poaceae family found in the Lembuak Kebon village area. Poaceae family plants are identified by matching morphological characters using various literature such as books, journals, and websites. Tools and materials used in mini research activities are stationery, rulers, meters, and smartphone cameras to record and document the types of Poaceae family plants found. Data analysis presented descriptively consists of roots, stems, leaves, flowers, and seeds of Poaceae family plants. mini research and observations that have been carried out on Sunday, May 26, 2024 in the Lembuak Kebon area, Narmada sub-district, West Lombok, there are 8 species from the Poaceae (Gramineae) family which are included in angiosperms, namely: Pennisetum purpureum, Panicum maximum, Cynodon dactylon, Eleusine indica, Zea mays, Panicum dichotomiflorum, Oplismenus undulatifolius, and Gigantochloa apus.
Pengaruh Model Pembelajaran Inkuiri Terbimbing dengan Leaflet 3D terhadap Motivasi dan Berpikir Logis Siswa Kelas VII MTSN 2 Mataram
Authors: Usnah Meilani  , Suhirman  , Rahman Firman
Published: January 2025

This study aims to evaluate the impact of using a guided inquiry learning model supported by 3D leaflet media on the learning motivation and logical thinking skills of seventh-grade students at MTsN 2 Mataram. The research method applied is a quasi-experiment with a non-equivalent control group design. The research sample consists of two classes: class VII C as the experimental group implementing the guided inquiry model with the aid of 3D leaflets, and class VII B as the control group using conventional learning methods. The research instruments include a learning motivation questionnaire in the form of an observation sheet and a logical thinking skills test consisting of a pretest and posttest. The results indicate a significant increase in the learning motivation and logical thinking skills of students in the experimental class compared to the control class. The use of 3D leaflet media has proven effective in supporting the guided inquiry learning process, making it an alternative learning strategy that can enhance the quality of education. These findings are expected to contribute positively to the development of innovative and interactive learning models at the secondary school level.
THE ROLE AND IMPORTANCE OF SOCIAL MEDIA ON WOMEN ENTREPRENEURSHIP – A STUDY WITH SPECIAL REFERENCE TO CHENNAI CITY
Authors:   Assistant Professor, Department of Commerce (Accounting and Finance, SRM IST FSH, Vadapalani, Chennai., Fernando Dr. Mary Sudharshini , M. Ms. Keertana ,   Assistant Professor, Department of Commerce (Accounting and Finance, SRM IST FSH, Vadapalani, Chennai.
Published: January 2025

Social media has emerged as a transformative tool for entrepreneurs worldwide, providing unprecedented opportunities for business growth and market outreach. Women entrepreneurs, in particular, have significantly benefited from social media platforms, which help overcome traditional barriers to entry in the business world. This article explores the critical role and importance of social media in fostering women entrepreneurship in Chennai, emphasizing its impact on business visibility, networking, market access, and skill development. Insights from quantitative research indicate that trust, accessibility, and multi-channel strategies significantly influence the effectiveness of social media use among women entrepreneurs.
HARNESSING PERSONALIZED EMOTIONAL AI FOR ENHANCED CONSUMER ENGAGEMENT IN INTELLIGENT MARKETING
Authors:   Assistant Professor, Department of Commerce, FSH, SRMIST, Vadapalani Campus, Chennai – 600 026, M Dr. Padmavathy.A, , Alamelu Dr. R.Aarthi ,   Assistant Professor Department of Commerce (Accounting & Finance),  FSH, SRMIST, Vadapalani Campus, Chennai – 600 026
Published: January 2025

In today's rapidly evolving digital landscape, the fusion of Artificial Intelligence (AI) with marketing has opened new avenues for creating personalized consumer experiences. One of the most innovative advancements in this realm is the use of Personalized Emotional AI. This technology harnesses the power of AI to analyze and respond to consumers' emotions in real-time, allowing brands to tailor their marketing strategies in ways that resonate deeply on an emotional level. By interpreting facial expressions, voice tones, and other biometric data, Emotional AI enables businesses to craft messages that connect with consumers' feelings, enhancing engagement and fostering stronger brand loyalty. This study explores the transformative potential of Personalized Emotional AI in modern marketing. Through a comprehensive analysis of its applications across various industries, the research delves into how this technology can elevate consumer interactions from merely transactional to profoundly relational. The findings indicate that when brands effectively utilize Emotional AI, they not only capture attention but also build lasting emotional bonds with their audiences. However, the implementation of Emotional AI comes with ethical considerations, particularly regarding privacy and the potential for emotional manipulation. This study underscores the importance of balancing innovation with responsibility, ensuring that the use of Emotional AI is transparent and respects consumer trust. By adopting a human-centered approach to AI, brands can harness its full potential to create meaningful, emotionally intelligent marketing campaigns that resonate with consumers on a deeper level, driving both engagement and loyalty.
Use of a shade guide to test the perception and prevalence of natural tooth colour in people of Nepal
Authors: Manu Rana  , Sandeep Sharma
Published: January 2025

Background: Recent advances in colour matching have been driven by the market demand for high-quality esthetic restorations. Improved shade guides, availability of shade-taking devices and research in the area of human colour vision have improved the potential of clinicians to achieve excellent colour matched restorations. A thorough understanding of appearance attributes of natural teeth is required along with these new tools to maximize shade matching results.
Aims and Objectives: The aim of the present investigation is to determine tooth shade among the people of Nepal.
Materials and Methods: In the present study, shade of cervical, middle and incisal third of the facial surface of natural maxillary central incisor was measured with digital colorimeter, VITA Easy shade Advance 4.0. It is an optical reading device that can assess the wavelengths reflected back to its sensors. Lighting in operatory does not affect the shade measurement. It is extremely accurate. The limitation of study was its small sample size.
Result: The shade obtained in the cervical third of tooth is 1M2 (37.33%), in the middle 1M1 (32.88%), and in the incisal third 2M1 (37.33%). Value 1 indicates lighter tooth colour and colour saturation is up to 2.
Conclusion: It was concluded that the most prevalent shade in cervical third was 1M2, middle third was 1M1 and incisal third was 2M1.
Morphological spectrum of atherosclerotic lesions in a tertiary care Institute in Punjab
Authors: Rajiv Kumar Gupta  , Tyagi Ruchita , Vikrampal Singh  , Samir Kapoor  , Gurmeet Singh  , Sarju Ralhan  , Pavneet Kaur Selhi  , Bhavna Garg  , Harpreet Kaur  , Neena Sood  , Naved Aslam  , Gurpreet Singh Wander
Published: January 2025

Background: The incidence of coronary artery disease (CAD) has risen considerably in developing world due to industrialization, urbanisation and lifestyle changes, especially among Indians and South Asians. The onset of CAD has been seen to occur at an early age and the severity of the disease and mortality associated with CAD has also increased. The pathology of atherosclerosis needs to be re-evaluated to develop targeted therapy which can contain the disease process at the earliest stage.
Aims and Objectives: Most of the morphological studies on atherosclerosis have been done on autopsy cases. In this study, we have analysed the morphological spectrum of atherosclerotic lesions in live patients.
Materials and Methods:  We retrospectively analysed the histopathology slides of 85 cases whose endarterectomy plaques were received in the Department of Pathology over a period of three and half years (January 2014 to June 2017) and classified the lesions according to Modified American Heart Association classification of atherosclerosis.
Results: The average age of patients was 60 years and male to female ratio of 4.3:1. Left anterior descending artery was the commonest vessel involved (52.4%). Majority of the cases had fibrocalcific plaques,followed by fibrous cap atheroma and calcified nodules.
Conclusion: Coronary artery plaques were found even in patients less than 40 years old.  Aggressive lipid defense therapy needs to be the cornerstone of management of CAD.
A reversible hypocalcemic dilated cardiomyopathy caused by primary hypoparathyroidism
Authors: Zhenli Cheng  , Shiv Kumar Yadav  , Xiaoyan Liu  , Qijian Yi
Published: January 2025

Dilated cardiomyopathy (DCM) is characterized by dilation and impaired contraction of one or both ventricles. Affected patients have impaired systolic function and may or may not develop overt heart failure (HF). Prognosis is generally poor without heart transplantation. We experienced a case of a 10-year-old child with dilated cardiomyopathy (DCM) accompanied by undiagnosed primary hypoparathyroidism. In our case,aggressive management of hypoparathyroidism significantly improved the manifestations of DCM. The case presentation highlights the importance of considering hypoparathyroidism as a cause of reversible myocardial dysfunction.
Parkinsonism following basal ganglia infarction in Dengue fever
Authors: Robin George Manappallil  , Pradeep Kumar V.G.  , Apurva Rao K.S.
Published: January 2025

Dengue fever is an acute febrile viral illness characterized by severe headache, myalgia, arthralgia, rashes, leucopenia and thrombocytopenia. Patients may face haemorrhagic complications like gastrointestinal bleeding, intracranial haemorrhage, menorrhagia, hematomas, hematuria and massive epistaxis. Ischemic stroke in dengue fever is a rare scenario; and Parkinsonism following basal ganglia infarction in dengue fever, to the best of our knowledge, has not been reported yet.
Severe Ovarian Hyperstimulation Syndrome despite low dose stimulation in Polycystic Ovarian Syndrome
Authors: Robin George Manappallil  , Sivadas Vilakupadath Kokoori  , Nandini Valsala
Published: January 2025

Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication of assisted reproduction technology. There is cystic enlargement of the ovaries along with fluid shift from the intravascular compartment to the third space due to increased capillary permeability and ovarian neoangiogenesis. Severe OHSS is uncommon and the condition can be fatal. Low-dose gonadotropin protocols have been introduced to reduce the risk of OHSS in patients with polycystic ovary syndrome (PCOS). The patient being reported had PCOS and developed severe OHSS despite low dose gonadotropin stimulation; which is a rare scenario.
Enterobius vermicularis in anterior chamber of eye
Authors: Kabindra Bajracharya  , Arjun Malla Bhari  , Salma KC Rai  , Saraswati Pandey
Published: January 2025

Enterobius vermiculari which is often referred as pinworm, is an intestinal nematode which is transmitted through fecal-oral route. The extraintestinal presentation of the worm is rare.  A live worm, Enterobius vermicularis in anterior chamber is a very rare case. To present an unusual case of Enterobius vermicularis in anterior chamber of right eye in a 3 years old girl. Visual acuity assessment, slit lamp examination and ultrasonography of the eye were performed. The worm was found in anterior chamber of right eye at 8-9 o' clock hour position, coiling at the presentation. The living, white worm was freely moving and changing position frequently. There was hypopyon with exudates inferiorly. The pupil was irregular, posterior synechiae was present with cataractous lens. The living worm was removed surgically under general anesthesia and sent for microbiological examination. Synecholysis with lens aspiration and Posterior chamber intraocular lens implantation was done in second surgery. An adult worm in anterior chamber is rare. Treatment is surgical removal. The visual prognosis is not good when the case present with severe form of anterior uveitis and complicated cataract.
Comparison of Kirschner wires and Cannulated screw internal fixation for displaced lateral humeral condyle fracture in children
Authors: Pabin Thapa  , Krishna Sapkota  , Krishna Wahegaonkar  , Niraj Ranjeet  , Pratyenta Raj Onta  , Upendra Jung Thapa
Published: January 2025

Background: Lateral condyle fracture of the distal humerus is the second most common injury around the elbow.
Aims and Objective: The purpose of the study was to compare Kirschner wires (K-wire) and Cannulated cancellous (CC) screw for internal fixation of displaced lateral humeral condyle fracture in children.
Materials and Methods: Forty-six patients with a displaced lateral condyle fracture of humerus were included in the study. Patients were treated with open reduction and internal fixation either with two 1.8mm K-wires or one 4mm CC screw. Fractures were classified according to Milch classification and clinical outcomes were evaluated according to criteria of Hardacre et al.
Results: There were 23 patients in each group with the mean age of 6.57 years (range 2 to 12 years). Milch type II was common (n= 34) than Milch type I (n=12). Fracture union was observed at mean 4.13 weeks in the CC screw and 4.61 weeks in K-wire group.(p value = 0.026). On an average the CC screws were removed at 13.57 weeks and K-wires were at 4.57 weeks. The mean follow-up was 13.83 months in CC screw and 12.52 months K-wire group. Three patients (6.5%) had superficial pin site infection and 2 patient (4.3%) had lateral condyle prominence in the K-wire group and only one lateral condyle prominence (2.2%) was observed in the CC screw group. According to the Hardacre et.al criteria CC screw group were excellent in 20 (87%) and good in 3 (13%) patients whereas 13 (56.5%) excellent and 10 (43.5%) good results were found in the K-wire group. (p value = 0.022).
Conclusion: Open reduction and internal fixation with either K-wires or cannulated cancellous screw for displaced lateral condyle fracture of humerus are both effective treatment methods but screw fixation provides absolute stability at the fracture site enhancing the fracture healing, reduces the probability of lateral prominence and allows early range of motion and activity in the affected elbow.
Initial presentation of Hodgkin’s Lymphoma as Extradural Spinal Cord Compression: A case report
Authors: Rishav Mukherjee  , Sampurna Chowdhury
Published: January 2025

A 23 year old female presented with acute onset paraparesis. She denied any history of fever, weight loss or drenching night sweats. Neither did she have any obvious lymphadenopathy on general examination. Chest Xray was however suggestive of mediastinal widening and her MRI spine showed metastases with superior mediastinal SOL. Biopsy of this SOL ultimately revealed classical Hodgkin lymphoma. Thus this was a very unusual initial presentation of Hodgkin lymphoma presenting as Epidural Spinal Cord Compression. Hasenclever IPS score was 2. Patient was treated with radiotherapy followed by ABVD chemotherapy and achieved remission in 3months.
Phytotherapeutic antioxidants
Authors: Tulika Mishra  , Ananda Kumar Kondepati  , Shalini Devaprasad Pasumarthi  , Gurmit Singh Chilana  , Suresh Devabhaktuni  , Pratik Kumar Singh
Published: January 2025

Plants have always been an integrated part of human life, whether we discuss about providing food or we about their medicinal value. Ethnomedicines have led to the discovery of many valuable drugs against various diseases. It has been postulated that most of the disease are related to immune system which is affected by imbalance balance between antioxidants and prooxidants or free radicals. Free radicals are the chemical entities capable of independent existence that contain one/more unpaired electrons and can be balanced by antioxidants. Antioxidants maintain the integrity and function of membrane lipids, cellular proteins, and nucleic acids and the control of signal transduction of gene expression in immune cells. For this reason, the immune cells are particularly sensitive to changes in their antioxidant status. Whenever there is imbalance between prooxidant and antioxidants they can lead to many diseases and even ameliorate the severity of disease like Alzheimer, cardiovascular disorder, cancer etc. There are evidences showing usage of plants as a potent source of antioxidants has provided a lot of support in combating various diseases, without any side effect. Various Bioflavonoids, Carotenoids, Hydroxycinnamates etc helps in scavenging the free radicals and thus proved to be immunostimulant. There are various mechanisms through which these Phyto antioxidants assisted against various disease. The present review is an attempt showing the relationship of free radicals with various diseases and immune system and the role of Phyto antioxidants against various health related conditions.
The proportion hyperhomocysteinemia in chronic kidney disease patients
Authors: Rizaldy Taslim Pinzon  , Rosa De Lima Renita Sanyasi  , Esdras Ardi Pramudita
Published: January 2025

Background: Chronic kidney disease (CKD) patients often have a high homocysteine level Hyperhomocystinemia considered as one of cardiovascular disease risk factor in CKD patients. Studies concern on the proportion of hyperhomocysteinemia in patients with CKD in Indonesia are very limited.
Aims and Objectives: The main objective was to identify the proportion of hyperhomocysteinemia in CKD patients.
Materials and Methods: This was a cross sectional study. Subjects in this study were CKD patients with routine hemodyalisis two times per week. Five mililiters venous blood was collected before the first hemodyalisis. The blood was stored into tubes contain clot activator. Homocysteine level higher than 15.39 μmol/L considered as hyperhomocysteine.
Results: Total of 122 subjects included at this study. Subjects dominated by male with mean age of 51.7 years. Anemia (86.9%) and hypertension (86.1%) were the common comorbidities. Co-treatment assessed in this study i.e.: folic acid, calcium carbonat, antihypertensive agent, antidiabetic agent, antiplatelet agent, lipid lowering agent, and hematopoietic agent. The prevalence of hyperhomocysteinemia was high (89.3%) despite of the high consumption of folic acid in subjects (86.1%).
Conclusion: Hyperhomocysteinemia is a common condition among CKD patients with hemodyalisis.
A case of Plus minus lid syndrome with Hypesthesia- Hemiataxia
Authors: Sinjan Ghosh  , Gautam Guha  , Manoj Kumar Roy  , Annesh Bhattacharjee  , Nikhil Repaka  , Sourav Nanda  , Niraja Agasti
Published: January 2025

We present the case of a patient with paramedian mesencephalic and ipsilateral thalamic infarction with an unusual clinical presentation, where the diagnosis and accurate anatomical localization were imperative for a unique clinicoradiological correlation.
Our patient was a 42-years old, right-handed Indian gentleman with hypertension who presented following acute myocardial infarction. He developed acute diplopia, left ptosis and right eyelid retraction. There was an associated hemiataxia and diminished sensation in right half of body.
Plus-minus lid syndrome and hemiataxia - hypesthesia are two different clinical syndromes. A co-association of these two syndromes in the same patient is rare which was evident in our case.
Matrilin-3 gene polymorphism in primary knee osteoarthritis: An Evidence based systematic review
Authors: Anurag Shukla  , Arun Kumar Sharma  , Rajbeer Singh  , Devendra Singh  , Ramesh C Meena  , Divyanshu Goyal  , Priyanka Sharma  , Uday Raman
Published: January 2025

There have been few studies in English literature identifying the potential association and clinical significance of MATN-3 rs8176070 (SNP6) polymorphism in patients with primary knee Osteoarthritis Knee. Objective of this paper was to evaluate the association of matrilin gene-3 and primary osteoarthritis of knee through systematic review of these studies. We did an extensive literature using relevant keywords .3 eligible studies were included for systematic review. Two studies showed significant association, in which Patients with the B\b genotype had worse clinical and radiological findings than those with B\B and b\b genotype. The third study in Indian population did not find any correlation. On the basis of this systematic review we can safely suggest that there is dearth of such studies in literature therefore more of such studies with wider and larger study population shall be undertaken to find Correlation of genetic in this multifactorial disorder and possible cure.
Understanding youth with substance use disorders (SUDs) in Rwanda: A health promotion perspective
Authors: James Ngamije  , Yadufashije Callixte
Published: January 2025

Youth drug abuse has been subject of public concern for many years. In Rwanda, despite nearly two decades of developing prevention initiatives, the problem persists with significant disparities present across the country. This review evaluates a health promotion perspective that addresses the specific needs of vulnerable youth.
Role of probiotics in respiratory tract diseases with special reference to COVID-19: A review
Authors: Aditi Munmun Sengupta  , Diptendu Chatterjee  , Rima Ghosh
Published: January 2025

According to the International Scientific Association in association with Food and Agriculture Organization of United Nations(UN) and World Health Organization (WHO), “administration of probiotics” means administration and ingestion of live microorganisms in an appropriate amount for developing good health condition in the host individual.
Probiotics are administered for building immunity against common respiratory tract  infections, including cough, pharyngitis, laryngitis, pneumonia, and asthma. Therefore, vaccinations have been introduced to safeguard the children and the elderly from such infections. General patients improve their health when they consume appropriate amounts live microorganisms (probiotics) such as Lactobacillus and Bifidobacterium that belong to lactic acid bacteria family. Fermented foods, such as yogurt and soy, and dietary supplements are known to be rich sources of microorganisms. However, the consumption of microorganisms causes gastrointestinal symptoms as common side effects. Limited studies provide relevant information about the probiotics’ consumption; therefore, the current study aimed to increase the probiotics consumption among individuals and avoid common infections.
Nonspecific food dependant exercise-induced anaphylaxis with seizure: a case report
Authors: Ummer Karadan  , Robin George Manappallil  , Ivin Panakkel Zacharia  , Thushara Anand
Published: January 2025

Exercise has been associated with several systemic reactions. These reactions can vary from mild symptoms to life threatening situations like anaphylaxis. In many of these cases, a predisposing factor in the form of food has been noticed. People may develop anaphylaxis on exercising after consumption of a nonspecific or specific food item. The patient being described developed anaphylaxis with seizure on exercising after having his meal. Nonspecific food dependant exercise-induced anaphylaxis is a rare scenario. Proper history taking is essential, as it can be lifesaving.
Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case report
Authors: Sampurna Chowdhury  , Rishav Mukherjee  , Pradip Kumar Sinha
Published: January 2025

Orientia tsutsugumashi ( erstwhile Rickettsia tsutsugumashi) is an obligate intracellular bacteria that is showing re-emergence in the last decade in eastern India 1-3. Commonly it causes acute febrile illness with rash and multiple organ involvement including CNS - In fact, Scrub encephalopathy has become a common cause of AES in recent times. Although pathogenesis of Scrub typhus is still uncertain, research on other Rickettsiales suggest infection of endothelial cells and vascular dysfunction to be the main mechanism. Based on that pathology we report two very rare manifestations - Acute Ischaemic Stroke and DVT in a single patient of Scrub typhus, occurring simultaneously. No such simultaneous occurrence has been reported in literature till date.
Food-dependent exercise-induced anaphylaxis following intake of nuts
Authors: Robin George Manappallil  , Thushara Anand
Published: January 2025

Allergic reactions can be mild or life threatening. Food-dependent exercise-induced anaphylaxis (FDEIA) is a severe form of allergic reaction in which symptoms develop only after exercising within a few hours of eating a specific food. The condition is, at times, underdiagnosed. Proper history taking is essential, especially when patients present with allergic reactions after exertion and food intake. The patient being described developed FDEIA because of exercising after eating nuts.
The intravenous use of commercial disinfectants in the treatment of Novel Coronavirus (COVID-19): Unconventional, but is there evidence against it?
Authors: Adarsh Shah  , Edmund Leung
Published: January 2025

Background: On 24th April 2020, United States President Donald J. Trump suggested the use of commercial surface disinfectants to treat patients infected with COVID-19. In his speech, President Trump also proposed medical research be conducted. However, there are controversies regarding the toxicity of the disinfectant’s main ingredients sodium hypochlorite.
Aims and Objective: The purpose of this international collaborative study is to assess on feasibility and safety of disinfectants in human use.
Materials and Methods: Several safety labels of common commercialised brands of surface disinfectant from United Kingdom and New Zealand. Furthermore, literature search was conducted through Pubmed on keywords keywords “sodium hypochlorite” AND “poisoning” AND “intravenous drug user”.
Result: All safety labels advised hazardous warning regarding irritation and caustic burns if ingested. They all suggest water to wash out the effect if exposed to any mucus membrane such as eyes and broken skin. No safety information was given by any of the brands against subcutaneous or intravenous injection. No death in human was reported resulting from oral ingestion. There were 2 case reports: one of blindness and one of fibrosing alveolitis resulting from ingestion during a domestic dispute. Intravenous injection has only been seen in attempted murder cases or by intravenous drug users. All the reported cases have resulted in 2 deaths, organ failures and venous thrombosis including pulmonary embolism.
Conclusion: There is no safety warning from the manufacturers of the studied surface disinfectants regarding intravenous use. Intravenous injections in the literature suggests significant toxic outcome including death. Randomised controlled trials on animals may be required to assess the risk of intravenous injection of surface disinfectants against the risk of death from COVID-19 infection.
Subtrochanteric fracture in a near term pregnant female in the back drop of COVID-19 pandemic: A triple trouble pregnant with peril all along
Authors: Arun Kumar Sharma  , Divyanshu Goyal  , Ramesh C Meena  , Mahesh C Bansal  , Rajesh Kumar Sharma  , Sanjeev Kumar
Published: January 2025

Outbreak of severe acute respiratory syndrome corona virus was first reported in Wuhan province in China. By February all hell broke loose in Europe and other continents. Spread of virus in India with 1.38 billion population posed an unprecedented challenge to its health care system. We hereby report a rare case of subtrochanteric fracture of femur in a near term (35 weeks) pregnant female who was treated at our tertiary care center in the times of Covid-19. Combination of pregnancy and Subtrochanteric femoral fracture is a double trouble with high morbidity and mortality and in time of Corona pandemic it became a unique challenge where two lives were at risk. Here we share our experience of dealing this case with multidisciplinary approach and sticking to our clinical sense as literature for Covid-19 pandemic is barely 4 months old and devoid of any guideline for such cases so far.
Parainfectious vasculitis due to Pneumococcal meningitis following traumatic CSF rhinorrhoea resulting in cerebellar infarction
Authors: Ummer Karadan  , Robin George Manappallil  , Manoj Bhaskaran  , Anoop Chandran  , Ivin Panakkel Zacharia
Published: January 2025

Parainfectious vasculitis is a rare life threatening complication of Streptococcus pneumoniae (S.pneumoniae) meningitis. There is a 19% risk of developing meningitis in the patients with cerebrospinal fluid (CSF) rhinorrhoea. The patient being reported developed CSF rhinorrhoea due to traumatic fracture of cribriform plate, followed by pneumococcal meningitis and parainfectious vasculitis resulting in cerebellar infarction.
COVID 19: An Epidemiological and Host Genetics Appraisal
Authors: Bandyopadhyay Arup Ratan
Published: January 2025

Letter to Editor
From the Desk of Editor
Authors: Kumar Arun
Published: January 2025

Dear All Associated Users of AJMS:
It gives us immense pleasure to publish the current issue of AJMS Vol 12 No 1 (2021). We started our journey from 2010 with an online edition of AJMS. Slowly we progressed with the support of our committed and strong team of Editorial board members and launched the printed edition in the year 2015 and we further expanded our publication frequency from quarterly issue to bimonthly issue.
With the overwhelming response and support from our users, we now take a leap to publish monthly issue from this year (2021) onwards.  With the current expansion of edition, we make it clear that we have not made any compromise in the quality of articles which we publish in AJMS. We have been striving hard to serve the potential authors who has entrusted on us and chosen our journal to publish their manuscripts, making our journal as their journal of choice!
On submission, the manuscripts are assigned to editor and section editor for initial review process, followed by assigning the manuscript to three reviewers of which two are internal reviewers and one outside the editorial board (external reviewer). The blind review process in our journal takes six to eight weeks’, sometimes even earlier depending on the reviewers and the decision is made once the review report is submitted to the editor.
Sometimes the delay in turnaround time happens which is unavoidable due to late response from reviewers and from the authors. We insist the authors to communicate with the editor soon the review reports are sent to them for revisions. This would further shrink the time of publication from submission. The reviewers and the editorial board members are solely responsible for taking initial decision of the article but the final decision is based on the Editor. The best part of our journal is we respond to each and every author promptly and do not ignore any queries. 
The details of the journal can be viewed by clicking the links of particular sections- Focus and Scope, Peer Review Process, Open Access Policy, Publication Frequency, Publication Ethics and Publication Malpractice Statement of Asian Journal of Medical Sciences, Duties of Reviewers, Duties of Authors, Indexing of Asian Journal of Medical Sciences can be viewed by this link-https://www.nepjol.info/index.php/AJMS/about
Submission Preparation Checklist, Author Guidelines, Plagiarism Policy can be viewed by following this link-https://www.nepjol.info/index.php/AJMS/about/submissions
Authors are advised to go through the guidelines and then submit their manuscripts
We look forward to further enhance the quality of article in AJMS and we will strive hard to ensure this journal goes global, in the future.
Thank you all for your support and entrusting on us.
Prof. Dr. Arun Kumar
Editor-in-Chief, Asian Journal of Medical Sciences
Study of clinical profile of dermatophytosis in a tertiary care center as per ECTODERM guidelines
Authors: Shitij Goel  , Shivam  , Azra Ferheen Chaudhary
Published: January 2025

Background: Dermatophytic infections are one of the most common skin infections encountered by dermatologists. A recent increase in incidence has been seen over the last few years with substantial change in the clinical profile of patients. Recently a group of dermatology experts published Expert Consensus on The Management of Dermatophytosis in India (ECTODERM India). The group agreed upon various definitions with respect to current dermatophytosis epidemic as well as gave recommendations for investigations and management. Clinical profile of dermatophytosis was done in present study on the basis of definitions agreed upon by ECTODERM consensus group.
Aims and Objective: To assess the clinical profile, prevalence and severity of dermatophytic infection in study population.
Materials and Methods: Cross-sectional observational study was conducted at out-patient department of Dermatology in, Sharda hospital, Greater Noida. A total of 317 patients presenting with clinical diagnosis of dermatophytosis were included in the study.
Results: A total of 317 patients were recruited in the study, out of which 213 were males (67.2%). The most common age group presenting with superficial dermatophytosis was 21-30 years. Majority of the patient presented with chronic dermatophytosis with duration more than 6 months (76.6%) while more than 3 lesions of tinea were observed in 76.6% cases. 191 patients (60%) had moderate to severe involvement with more than 3% of BSA involved. Family members presenting with similar complaints were seen in 39% cases. Majority of patients (76 %) studies had received previous treatment topical, systemic or both. 62 patients presented with recurrence of disease within 6 weeks of complete antifungal treatment (19.6%).
Conclusion: Our study concludes that dermatophytosis still remain a challenging issue for dermatologists. Chronicity of infection, moderate to severe BSA involvement and involvement of family members in a good proportion of our study cases were the main findings of our study.
Esophageal Motility Disorders in patients with Gastro-Esophageal Reflux Disease diagnosed by using High Resolution Esophageal Manometry- data from the developing world
Authors: Zain Majid  , Syed Mudassir Laeeq  , Muhammad Manzoor ul haq  , Farina M Hanif  , Shoaib Ahmed Khan  , Abbas Ali Tasneem  , Nasir Hassan Luck
Published: January 2025

Background: Gastro-esophageal reflux disease (GERD) has a prevalence of 10-20% in the Western countries while its prevalence amongst the Pakistani population is between 22 to 24%. Esophageal manometry is currently the gold standard for diagnosing esophageal motility disorders.
Aims and Objectives: To determine the frequency of esophageal motility disorder in patients with GERD.
Materials and Methods: This cross-sectional study was conducted at the department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Patients diagnosed with GERD (defined as having typical reflux symptoms with more than 2 episodes per were) were included in this study. These patients were subjected to upper GI endoscopy followed by esophageal manometry. Esophageal motility disorders were then classificated by using the Chicago classification 3.0.
Results: A total of 76 patients were included in our study, out of which 41 (53.9%) were females. A mean age of 46.1 years ± 12 years and a mean body mass index (BMI) of 23.7kg/m2 was noted. The most common comorbid condition seen in our patients was diabetes mellitus, which was seen in 13 patients (17%). A normal EGD was noted in 48 patients (63%). Liquid perfusion esophageal manometer catheter was mainly used in our study that is in 70 patients (92.1%). Weak esophageal peristalsis was the most common esophageal motor abnormality seen in 16 patients (21.1%).
Conclusion: A significant proportion of patients with GERD have the presence of a motility disorders, the early identification and treatment of which can lead to improvement GERD symptoms.
Pulmonary function test correlation with subclinical respiratory dysfunction in chronic cervical cord compression
Authors: Manpreet Singh Banga  , Sandeep BV  , Anantha Kishan  , Rajesh Babu Devabhakthuni  , Arun MA  , Arjun H Dev
Published: January 2025

Background: To assess respiratory function in cervical chronic compressive myelopathy (CCM) patients in pre-operative period, post-operative period and to compare pre-operative status with post-operative status.
Aims and Objectives: 1. To assess respiratory function in cervical CCM patients in pre-operative period. 2. To assess respiratory function in cervical CCM patients in post-operative period, following relief of compression. 3. To compare, pre-operative status with post-operative status.
Materials and Methods: A prospective study was done in 50 patients with cervical CCM due to either cervical disc disease or ossified posterior longitudinal ligament (OPLL) who were operated. None of the patients included in the study had any clinical signs & symptoms of respiratory dysfunction. Spirometry was performed in pre-operative and postoperative period after 3 months and results were analyzed. Forced vital capacity (FVC), forced expiratory volume in first second (FEV1), ratio of mean FEV1 to FVC (FEVI: FVC%) and peak expiratory flow rate (PEFR) were calculated.
Results: Majority of the patients were in their fourth decade of life with male predominance. Thirty-six patients (72%) presented with prolapsed intervertebral disc and 14 patients (28%) had ossified posterior longitudinal ligament (OPLL). Patients were operated depending upon the pathology. The present study showed that there was significant reduction in preoperative FVC, FEV1, PEFR values as compared with predicted values and they showed significant improvement in post-operative period after surgical relief of compression.
Conclusion: Significant yet occult respiratory dysfunction in form of impairment of various lung capacities exists in patients with cervical CCM. An objective evaluation of this occult respiratory dysfunction is essential to prognosticate, prevent respiratory complications and to improve post-operative respiratory rehabilitation. Institution of incentive spirometry as a routine in all cervical CCM cases will be of benefit in preventing respiratory complications.