bluuebunny/crossref_metadata_2025 huggingface dataset:
Absorption of methylene blue from aqueous solutions on activated coal CAN-9: kinetics and equilibrium studies
Authors:   Institute of Chemistry, Chisinau, Moldova, Lupascu Tudor , Ciobanu Mihail ,   Institute of Chemistry, Chisinau, Moldova, Culighin Elena ,   Institute of Chemistry, Chisinau, Moldova
Published: June 2022

The adsorption of methylene blue and kinetics of its adsorption from aqueous solutions on activated carbon CAN-9, obtained from walnut shells by chemical activation with orthophosphoric acid were studied. It has been shown that methylene blue adsorption isotherm from aqueous solutions on CAN-9 in the linear coordinates of the Langmuir model is a straight line (R = 0.99427) and is of Langmuir type. The kinetics of methylene blue adsorption on CAN-9, measured at two initial concentrations, showed an increase in Kint and C values with the increase of the initial concentrations. The process of intra-particular diffusion occurs in only one stage and takes place in the mesopores.
Geochemical assessment of soil and water in two protected areas from Valcea and Dolj Counties
Authors:   National Research and Development Institute for Industrial Ecology, Manea Catalin , Spinu Narcis Claudiu ,   National Research and Development Institute for Industrial Ecology, Popescu Luisa Roxana ,   National Research and Development Institute for Industrial Ecology, Draghici Mihaiela ,   National Research and Development Institute for Industrial Ecology
Published: June 2022

The purpose of this paper was to assess the quality of environmental factors such as soil and water in some protected areas in Romania. The chosen case studies were the Preajba-Facai lake system from Dolj County and the Vanturarita Buila National Park from Valcea County. Highlighting the evolutionary aspects of the analyzed quality parameters (20 physical-chemical indicators) on a spatial-temporal scale aiming at establishing geochemical thresholds is the final result of a larger project. The results presented in this article were obtained through seasonal monitoring involving water and soil sampling and laboratory analysis. All the results were interpreted in relation to the values in the specific environmental legislation, and following the field visits additional information was brought, which contributed to a good knowledge of these regions. The areas, although protected, are influenced by the anthropogenic factor, which has a negative impact on the environment. In some cases, non-compliances were identified and validated by the analysis performed.
Citrus Flavonoids and Autoimmune Diseases: A Systematic Review of
Clinical Studies
Authors: Musumeci Laura , Maugeri Alessandro , Russo Caterina , Lombardo Giovanni Enrico , Cirmi Santa , Navarra Michele
Published: June 2022

Background:

Autoimmune diseases are chronic disorders in which the immune system does not recognize and attacks one self’s healthy components. In this context, although natural remedies might represent a promising therapeutic strategy, evidence regarding Citrus flavonoids is still controversial.

Objective:

To summarize and critically discuss the clinical evidence on the effects of Citrus flavonoids for the management of autoimmune diseases.

Method:

A systematic review of articles has been carried out independently by two Authors using MEDLINE, Scopus and ISI Web of Science databases. Search terms comprised keywords related to Citrus flavonoids and autoimmune diseases. The last search was performed on March 16, 2021. No language restrictions were applied. Systematic review and study selection were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Before starting the review, Authors defined the types of articles to be included. Three reviewers independently carried out the extraction of papers.

Results:

Ten clinical studies fulfilled the eligibility criteria and were included in the final review.

Conclusion:

The studies discussed in this review are heterogeneous. Indeed, some studies suggest the use of Citrus flavonoids in the frame of autoimmune disorders, whereas others discourage it. Hence, this systematic review highlights the need of further large-scale clinical studies to define the exact role of Citrus flavonoids in the management of autoimmune diseases (PROSPERO number CRD42021234903).
An Overview on Immunity Booster Foods in Coronavirus Disease
(COVID-19)
Authors: Sahiba Nusrat , Sethiya Ayushi , Agarwal Dinesh K. , Agarwal Shikha
Published: June 2022

The present COVID-19 pandemic is terrible for the respiratory system and is caused by
severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). It has affected millions of people
globally and over 511.9 million cases and 6.2 million deaths have been reported across the world.
Various drugs have been repurposed, however, no specific medicine has been approved by the
FDA to combat this disease till date. In this condition, researchers have been attracted to natural
and safe products to improve immunity to viral infections through inhibiting viral cell entry, replication,
and modulation. Various natural products, probiotics, and nutrients have antimicrobial, antiviral,
analgesic, anti-inflammatory, and antiproliferative activities, and some of the compounds
are also utilized in traditional medicine in Ayurveda, Siddha, and other cultures. This review provides
a clinical perspective on the application of herbs for the prevention of viral infections.
Arsenic Trioxide Restrains Lung Cancer Growth and Metastasis by Blocking
the Calcineurin-NFAT Pathway by Upregulating DSCR1
Authors: Yang Meng-Hang , Zhao Xue-Wei , Li Bing , Wang Yu-Sheng , Shi Xiao-Qian
Published: June 2022

Background:

Anti-angiogenesis therapy mostly aimed at targeting vascular endothelial
growth factor (VEGF) and its receptors have been widely applied to lung cancer. However, the improvement
in the patient's overall survival remains dissatisfying. Previously, we demonstrated that arsenic
trioxide (As2O3) exerts an anti-lung cancer effect through anti-angiogenesis, but the details of the
mechanism in play remain unclear. Herein, we focused on the calcineurin-NFAT pathway, downstream
of VEGF, and its endogenous inhibitor DSCR1.

Objective:

To demonstrate the mechanism of As2O3 restraining lung cancer growth and metastasis by
blocking the calcineurin-NFAT pathway by upregulating DSCR1.

Methods:

We constructed xenografts and metastasis models based on wild-type (WT) and DSCR1
knockout (DSCR1-/-) mice, and carried out qPCR, Western blot, immunohistochemistry, in vivo imaging
and calculated microvessel density to evaluate the effects of As2O3 on angiogenesis, tumor growth,
metastasis, and the protein expression levels of DSCR1 and calcineurin-NFAT pathway-related molecules.

Results:

As2O3 inhibited tumor growth and metastasis, reduced microvessel formation, and induced
vascular lumen malformation in WT mice. At the protein level, As2O3 upregulated DSCR1, downregulated
NFAT2 and its downstream molecules, but had no effect on calcineurin A. However, in DSCR1-/-
mice, the above-mentioned effects of As2O3 were abolished.

Conclusion:

As2O3 can suppress lung cancer growth and metastasis through anti-angiogenesis effects
by blocking the calcineurin-NFAT pathway by upregulating DSCR1. The results shed light on the antitumor
mechanism of As2O3 and are a step forward in the identification of As2O3 as a new drug in the
treatment of lung cancer.
Advances in Stem Cell Therapy for Intestinal Diseases: Mechanisms, Perspectives
Regarding Clinical Applications, and Challenges
Authors: Fan Weiwen , Chang Le , Pan Xinghua , Zhu Xiangqing
Published: June 2022

Background:

Intestinal disease is a common disease, which can cause serious digestion and absorption disorders, endanger the lives of patients and seriously affect the quality of life of people. Finding an effective treatment is a difficult problem at present, and stem cell therapy as a treatment has high application potential in intestinal-related diseases.

Purpose:

This paper mainly summarizes the mechanism, research progress and future development trend of stem cells in the treatment of intestinal diseases in the past decade, hoping to provide reference for future researchers in the research and application of stem cells and intestinal diseases.

Method:

Stem cells, inflammatory bowel diseases, Crohn's disease, radiation-induced intestinal injury, radiation enterocolitis, and extracellular vesicles ' were used as search terms. Relevant references in the past ten years were searched in CNKI journal full-text database, PubMed database, VIP network and Wanfang medical network, and 80 literature meeting the requirements were finally included for review.

Result:

This paper summarizes the research and application of stem cells in intestinal diseases from 2012 to 2021, and expounds the specific mechanism of stem cells in the treatment of intestinal diseases. It is found that stem cells can treat intestinal injury or inflammation through different ways. Future stem cells may also be used to reverse the natural aging of intestinal function, improve intestinal function and strengthen gastrointestinal function.
Verifying the Theory of Climate Affecting Lethality of COVID-19 by an Analysis in Two Climatic Zones of Chile
Authors: Aviles-Gonzalez Cesar Ivan , Scano Alessandra , Cossu Giulia , Littera Roberto , Campagna Marcello , Deidda Simona , Romano Ferdinando , Kalcev Goce , Firinu Davide , Meloni Federico , Carta Mauro Giovanni , Del Giacco Stefano , Restivo Angelo , Zorcolo Luigi , Marongiu Luigi , Tamburini Giorgio , Maleci Alberto , Orrù Germano , Chessa Luchino , Brasesco María Verónica
Published: June 2022

Introduction:

The study of seasonal influences on the COVID-19 pandemic can take advantage of the unique position of Chile and its different climatic profiles in the north-south extension. The purpose is to verify the influence of seasonal climate changes on the COVID-19 in the temperate and sub-arctic areas of Chile.

Methods:

We monitored the evolution of CFR in temperate versus sub-boreal regions, reporting from the John Hopkins University COVID-19 Center on the CFR in each province in midwinter, spring, and early summer.

Results:

CFR worsened from mid-winter to mid-spring in the temperate zone of Chile, while in the sub-boreal area the CFR improves in the same period, (Kruskal Wallis Test, p=0.004). In the temperate zone after the increase in late winter-early spring, CRF tends to stabilize; on the contrary in the sub-boreal zone, there is a more marked tendency to worsen the CFR at the same time (Kruskal Wallis Test, p=0.010). The temperate zone of Chile shows a CFR increasing until spring-like temperate Europe, unlike Europe CFR does not decrease in summer, but the mean minimum temperature in temperate Chile is lower in summer than in temperate Europe. In Patagonian, CFR remains stable or drops from winter to spring but increases in early summer.

Conclusion:

The temperate and sub-boreal zones of Chile have a markedly different CFR variation profile during the COVID-19 pandemic.
ANALISIS SPASIAL DAERAH POTENSI RAWAN LONGSOR DI KOTA AMBON DENGAN MENGGUNAKAN METODE SMORPH
Authors: Rakuasa Heinrich , Supriatna S , Tambunan Mangapul Parlindungan , Salakory Melianus , Pinoa Wiclif. S.
Published: June 2022

The geographical condition of Ambon City, which is 75% a hilly area resulted in most communities building in marbled areas with slopes above 20%, which has the potential to threaten life and landslide disasters. This study simply looked at the influence of slopes and slope shapes in Ambon City that can be analyzed using geographic information systems (GIS) to map areas that have the potential for landslides. Identification and mapping of potential landslide areas have an important role as an effort in overcoming and anticipating the occurrence of landslide disasters. This study aimed to analyze the spread of potential landslide areas in Ambon City based on the results of SMORPH modeling. The study used the slope morphology or SMORPH method, which has a better degree of accuracy than the Storie Index and SINMAP methods to identify and classify potential landslide areas based on the matrix between slope shape and slope angle. This study resulted in 4 levels of landslide potential areas, namely very low, low, medium and high potential. Areas with high landslide potential dominate the northern and southern parts of Ambon City. In the region, most landslides occur in the form of sunken and convex slopes. The region has a hilly and mountainous topography with a steep slope. The results of this research using the SMORPH method can illustrate that the slope of the increasingly higher slope accompanied by the shape of a convex or concave slope will cause the potential for landslides that are higher in the region.
KEPADATAN SPORA DAN PERSEN KOLONI MIKORIZA VESIKULA ARBUSKULA (MVA) PADA BEBERAPA TANAMAN PANGAN DI LAHAN PERTANIAN KECAMATAN JABUNG MALANG
Authors: Alayya Nahdlia Putri , Prasetya Budi
Published: June 2022

Mycorrhizae is a symbiotic relationship between fungi and plant roots that is mutually beneficial. Mycorrhizae can be found in almost all soil types and generally do not have a specific host, but certain factors affect the population level and composition of arbuscular mycorrhizal species, such as plant characteristics and soil chemical properties. This study aimed to determine the density of spores and the percentage of mycorrhizal colonies on several food crops on agricultural land in Jabung District and their relationship to soil chemical properties such as pH, organic-C and available P. The research was conducted from February 2021 to October 2021. Sampling was carried out by purposive sampling based on the grouping of food plant species with six replications. Laboratory analysis was conducted in Biology and Chemical Laboratory, Department of Soil Science, Faculty of Agriculture, Brawijaya University. The results showed that the number of mycorrhizae spores per 100 g of soil was sweet potato (14.17 spores), rice (26.50 spores), cassava (70 spores), and maize (89.17). The percentage of mycorrhizal colonies on sweet potato (33.97%), cassava (50.67%), and rice (45.52%) were in the high category, while the percentage of mycorrhizal colonies on maize (63.68%) was in the very high category. Several mycorrhizae were found, including Glomus sp., Acaulospora sp., and Gigaspora sp.
Adat, Istiadat dan Budaya Melayu Kalimantan Dalam Perspektif Arsitektur
Authors: Zain Zairin , Akbar Muhammad Alif Khairil , Situmeang Meidycharlos Amos Ondion
Published: June 2022

Malays are one of several local ethnicities who inhabit the island of Kalimantan. Malay architecture can be linked to elements of customs, culture, and tradition that develop within the growth of ethnicity toward community development. Furthermore, many reports found that the characteristics of the environment and the settlements' location make a difference in the Malay house's traditional architecture on the island of Kalimantan. The study identifies some differentiation by the effects of cultural factors in each area of traditional architecture, affecting the architectural elements. The influences to Malay architecture are found differences by each region's customs, culture, and tradition. The Malays' customs, culture, and tradition greatly influence Malays houses' architecture because the culture is robust. This influence has made the customs, culture, and tradition become an obligation embedded in every Malay society. The embedded influences to the traditional Malay houses are found in the orientation of the openings, spatial arrangement, structure, and construction. The factor of being a Malay makes people attaching a unique meaning to the architecture of a traditional Malay house. The meanings follow the belief in environmental conditions and simplicity in Islamic teachings in traditional houses.
Strategi Penataan Permukiman Nelayan Keberlanjutan di Tepi Sungai Kaliyasa
Authors:   Program Magister Arsitektur, Universitas Katolik Soegijapranata, Ardhi Prabhaskara Henry , Rejeki V.G. Sri , Ardiyanto Antonius
Published: June 2022

The Kaliyasa River is a vital means for fishermen, especially traditional fishermen who live around the river. Since the construction of the Cilacap Fishing Port, many migrants started to settle and overtime the population crowded the area uncontrollably and marginalized. This study focused on the strategy of reorganizing fishermen’s settlements with a sustainable development and waterfront development approach as well as the regulation of PERMEN no. 28 of 2015, Descriptive-qualitative method has being used to explain the conditions in the study area, The data collection using desk study and field study methods, from the findings confirmed by the theory of waterfront and sustainable development in order to obtain the right reorganizing strategy. The result of this research is a settlement reorganizing strategy that applies the principle of waterfront development. This principle is applied through social aspects by creating open public spaces, piers placement, and public counseling about river border regulations. Environmental aspects with the arrangement of trash bins on the banks of the river as well as the establishment of waste management institution, management of green open spaces, and solution for illegal buildings in river bank areas. Economic aspects by improving dock infrastructure to support fishing activities, as well as reorganizing marine product trade zone. The preservation aspect aims to preserve the identity of the Kaliyasa river as water transportation route and fishermen's settlements.
Charles van Rysselberghe bouwt in Sint-Pieters-Buiten Gent, Koning Albertlaan en Lostraat, 1884-1920. Deel 2. Ontwikkeling van de Stationsbuurt-Noord, Gent-Sint-Pieters
Authors: Steeman Jan
Published: June 2022

Slechts vanaf de tweede helft van de 19de eeuw verstedelijkt de huidige Gentse stationsbuurt. Hiervoor zijn een drietal belangrijke redenen aan te halen: de Hollandse citadel die geleidelijk aan haar militaire nut verloor, de afschaffing van de octrooirechten in 1860 en de organisatie van de We reldtentoonstelling in 1913, waardoor de bouw van het Sint-Pieters station in een stroomversnelling kwam.
Hoe de Harmonie, nieuw peilschip voor North Sea Port, aan zijn naam kwam.
Authors: Taymans Huguette
Published: June 2022

In 2017 werd beslist om de Gentse haven en de havens van Zeeland te fusioneren tot North Sea Port. Deze grotere entiteit moet het mogelijk maken het havengebied, dat zich uitstrekt van het Nederlandse Vlissingen tot het Vlaamse Gent, verder uit te bouwen en economische groei te creëren door de diversificatie van sectoren en (handels)zones. Bij de zoektocht naar een naam voor een peilschip kwam men terecht bij een numismatisch artikel.
Minder bekende Gentse fotografen. Nestor Schaffers (1826 – 1896). Opvolger van Edouard Renoz
Authors: Verhoosele Françoise
Published: June 2022

Nestor Schaffers, ‘nestor’ van de Gentse fotografen, werd geboren als Paul Joseph Nicolas Nestor in Luik op 13 maart 1826.
Nevenactiviteiten in en rond de Heernessemeersen tijdens de late middeleeuwen.
Authors: Hanson Marc
Published: June 2022

Heel wat activiteiten van de bewoners van het Sint-Baafsdorp hadden te maken met het meersengebied grenzend aan de westelijke oever van de Nederschelde, dat bekend staat als de Heirnis, de ‘Heernesse’. In deze bijdrage gaan we nader in op enkele nevenfuncties en kleinschalige activiteiten in de Heernesse en haar randgebied. Behalve voor de kleine boeren, waren die van levensbelang voor nogal wat arme dorpsbewoners.
Mossels: vlees voor de arme in de jaren 1800
Authors: De Witte Pol , Andelhof Emiel
Published: June 2022

Zeemossels waren in de jaren 1800 in Gent, en wellicht ook in kuststeden en andere plaatsen met een goede zeeverbinding, een heel belangrijk en goedkoop volksvoedsel. Een beschrijving van de rol van mossels gekaderd in de algemene voedselsituatie, werd geplukt uit de memoires van Pol De Witte (1848-1929) die opgroeide in de buurt van het grote beluikencomplex Batavia, nu grotendeels het universitaire Platteaugebouw, maar tot in het laatste kwart van de 19de eeuw proletarisch tot en met.
Melk voor de Gentenaars (1882-1919). Stedelijke Koedienst, Werk van de Druppel Melk en Laiterie de Gand.
Authors: Devriese Luc
Published: June 2022

Dit artikel focust op de levensnoodzakelijke voorziening van melk aan de Gentse stadsbevolking tijdens en kort na de eerste wereldoorlog. Dat voedsel was vooral precair in de laatste oorlogsjaren 1917 en 1918 toen ons land een (voorlopig) laatste hongersnood kende. Enkele aspecten van dit thema worden kort belicht. Vooral stedelijke initiatieven komen aan bod. Om die ten volle te vatten, wordt ze ruimer gekaderd in het moeilijke dagelijkse leven van toen.
Sequah wonderolie Hoe wellness massage in 1892 succesvol aan de man werd gebracht.
Authors: Andelhof Emiel
Published: June 2022

Emiel Andelhof, populaire folklorist rond WO II , verhaalt over het ‘optreden’ van Giele in een publieke therapeutische sessie, of een show die daarvoor moest doorgaan. Zijn ‘vastgeroeste’ gewrichten werden ingewreven met ‘Prairie Flower’ wonderolie en stevig gemasseerd. Daarna mocht de man zijn herwonnen soepelheid demonsteren aan het publiek, dat deskundig opgestookt werd om de olie van de firma Sequah te kopen.
PREVALENCE OF ENDOCRINE PATHOLOGY AMONG INFANTILE POPULATION IN KHARKIV REGION
Authors: Khizhnyak Oksana , Tambovtseva T. K.
Published: June 2022

The article is devoted to investigating of main peculiarities of prevalence of endocrine pathology among infantile population in Kharkiv region. The estimation of efficiency of infantile population treatment is given according to the criteria of endocrine pathology prevalence.
THE RESISTIN LEVELS CHANGES IN HYPERTENSIVE PATIENTS IN DEPENDSE ON CONCOMITANT DIABETES MELLITUS TYPE 2 AND INSULIN RESISTANCE
Authors: Shkolnyk V. V.
Published: June 2022

The levels of resistin are studied on the background of insulin resistance or at presence of diabetes mellitus type 2 in patients with arterial hypertension, that is actual for introduction of new approaches in the estimation of insulin resistance, and for the account of resistin effects on metabolic processes at the choice of therapeutic methods, aimed at the decline of expressed of insulin resistance of peripheral tissue.
THE INFLUENCE OF DONOR’S SPLENOCYTES ADMINISTRAION ON SURVIVAL OF THYROID TISSUE FRAGMENTS AT TRANSPLANTATION
Authors: Bozhok G. A.
Published: June 2022

The influence of pretransplant administration of the splenocytes of donor’s origin on survival of thyroid tissue fragments of adult rats at transplantation was studied. It has been established that introduction of the splenocytes into portal vein of recipient’s liver 7 days before transplantation can lead to the allograft either acceptance or acceleration of rejection.
CHARACTERISTICS OF IMMUNHORMONAL RELATIONS AT THE STAGE LATE SEXUAL MATURATION IN HEALTHY TEENS AND OFFSPRING LIQUIDATORS OF THE CONSEQUENCES OF THE CHORNOBYL DISASTER
Authors: Plekhova O. I. , Shlyakhova N. V.
Published: June 2022

Immunoendocrine Relationships in 111 Practically Healthy 16-18 Year Old Children and 240 of their peers born of Chernobyl accident liquidators. Availability shown close relationships between immune system parameters and hormonal status in healthy teenagers. Imbalance and disintegration of immune and endocrine systems in offspring established liquidators of the consequences of the Chornobyl disaster.
NEUROVITAN IN COMPLEX TREATMENT AND REHABILITATION PATIENTS WITH HYPOTHYROIDISM
Authors: Vernygorodsky V. S. , Vlasenko M. V. , Fetisova N. M.
Published: June 2022

Clinical efficacy of the drug Neurovitan in the complex treatment of hypothyroidism was studied ulcerative polyneuropathies. It has been shown that for faster recovery of impaired pa it is genetically determined to prescribe drugs that have neurotrophic effects, in particular Neurovitan.
CHARACTERISTICS OF THE RELATIONSHIP BETWEEN THE LEVELS OF TRIODIOTHYRONINE AND THYROXINE IN WHITE RATS IN NORMAL AND EXPERIMENTAL HYPERTHYROESIS
Authors: Stanishevskaya T. I. , Sobolev V. I.
Published: June 2022

Regarding the euthyroid status, the regulation in the hormonal pair "T3free - T4free". carried out by the principle of "positive feedback", and in experimental hyperthyroidism, on the contrary - on the classic "negative feedback" principle. At the boundaries of the physiological norm of the level triiodothyrone regulation process in the hormonal pair "T3vil.-T4viln." in rats euthyroid groups are carried out with a high degree of variability. In hyperthyroid animals intercluster- their variance in the magnitude of the dispersion over the whole range of triiodothyron values ​​does not detected. The efficiency of the action of the unit of concentration of free T3 on the level of free T4 by euthyroid- status is significantly higher than that of experimental hyperthyroidism.
Development and testing a model of energy absorption in biological objects from incorporated photon emitters
Authors:   Research and Production Association “Typhoon”, Sazykina T.G. , Kryshev A.I. ,   Research and Production Association “Typhoon”
Published: June 2022

A new analytical method, previously developed for estimating beta absorbed fractions, was ex-tended for analytical estimating photon absorbed fractions in soft-tissue bodies from internal uni-formly distributed gamma emitters. The method involves a rescaling procedure with transfor-mation of real biological sizes to unitless effective ones combining information of both photon energy and object’s size. The rescaling was applied to large published datasets of photon ab-sorbed fractions in soft-tissue spheres. A new effect was demonstrated: the rescaled data were united into a single smooth “universal curve” with saturation. The universal curve for photon ab-sorbed fractions was described analytically as a function of a single argument – a rescaled effec-tive radius. Practical applicability of the approach for non-spherical convex bodies (ellipsoids) was demonstrated. Examples of analytical estimating the internal dose coefficients for repre-sentative terrestrial animals were calculated. The new method now available for electron and photon internal dosimetry, provides an effective analytical tool for calculating radiation absorbed fractions in organs and bodies of soft-tissue organisms.
HASTANE ATIKSULARINDAKİ MİKROKİRLETİCİLER VE MİKROKİRLETİCİLERİN MEMBRAN BİYOREAKTÖRLERDE GİDERİMİ
Authors: KARAKAŞ İnci , KAYA Yasemin , VERGİLİ İlda , ÖZÇELEP Zeren Beril , YILMAZ Gülsüm
Published: June 2022

Mikrokirleticiler, biyolojik olarak parçalanabilirliklerinin düşük olması sebebiyle ekosistemde birikme eğilimi göstermekte ve canlı hayatı için toksik, kanserojenik ve mutajenik etkileriyle büyük bir risk oluşturmaktadır. Yaygın olarak içme suları, yüzeysel sular ve yeraltı sularında da nanogram seviyesinde tespit edilen mikrokirleticiler; hastane atıksularında çok yüksek konsantrasyonlarda bulunabilmektedir. Ülkemizde hastane atıksuları doğrudan kanalizasyon sistemine verilerek, evsel atıksularla beraber ön arıtma yapılarak veya biyolojik atıksu arıtma tesisinde arıtıldıktan sonra alıcı ortama verilmektedir. Klasik atıksu arıtma yöntemleriyle atıksulardan giderilemeyen mikrokirleticilerin, ancak ileri atıksu arıtma yöntemleriyle giderimi mümkün olabilmektedir. Bu çalışmada, hastane atıksularındaki mikrokirleticilerin membran biyoreaktörde (MBR) giderimi ve işletme parametrelerinin giderim verimleri üzerine etkisi incelenmiştir.
Dearomatization of the Kerosene Fraction: Kinetic Studies
Authors:   Azerbaijan State University of Oil and Industry, Azadlig ave., 20, Baku AZ 1010, Azerbaijan, Ismayilova Sabira Sabir , Amirov Sabir Qarsh ,   Azerbaijan State University of Oil and Industry, Azadlig ave., 20, Baku AZ 1010, Azerbaijan
Published: June 2022

The kinetics of dearomatization of a kerosene fraction processed using a zeolite catalyst (0.9 HZSM-5) at different temperatures (160-200°C), the molar ratio between the aromatic hydrocarbons present in the kerosene fraction and n-decene (1:(0.5-4)), and the reaction time (1-3 h) were studied. Based on the obtained data, a kinetic model for kerosene dearomatization is proposed. It is assumed that the single-center Riedel mechanism is followed. The stage associated with the interaction between n-decene adsorbed on the surface of the catalyst containing aromatic compounds and n-decene present in the volume is identified as the limiting sage of the dearomatization process.
Using Twitter Data for Cohort Studies of Drug Safety in Pregnancy: Proof-of-concept With β-Blockers (Preprint)
Authors: Klein Ari Z , O'Connor Karen , Levine Lisa D , Gonzalez-Hernandez Graciela
Published: June 2022

BACKGROUND

Despite the fact that medication is taken during more than 90% of pregnancies, the fetal risk for most medications is unknown, and the majority of medications have no data regarding safety in pregnancy.

OBJECTIVE

Using β-blockers as a proof-of-concept, the primary objective of this study was to assess the utility of Twitter data for a cohort study design—in particular, whether we could identify (1) Twitter users who have posted tweets reporting that they took medication during pregnancy and (2) their associated pregnancy outcomes.

METHODS

We searched for mentions of β-blockers in 2.75 billion tweets posted by 415,690 users who announced their pregnancy on Twitter. We manually reviewed the matching tweets to first determine if the user actually took the β-blocker mentioned in the tweet. Then, to help determine if the β-blocker was taken during pregnancy, we used the time stamp of the tweet reporting intake and drew upon an automated natural language processing (NLP) tool that estimates the date of the user’s prenatal time period. For users who posted tweets indicating that they took or may have taken the β-blocker during pregnancy, we drew upon additional NLP tools to help identify tweets that report their pregnancy outcomes. Adverse pregnancy outcomes included miscarriage, stillbirth, birth defects, preterm birth (<37 weeks gestation), low birth weight (<5 pounds and 8 ounces at delivery), and neonatal intensive care unit (NICU) admission. Normal pregnancy outcomes included gestational age ≥37 weeks and birth weight ≥5 pounds and 8 ounces.

RESULTS

We retrieved 5114 tweets, posted by 2339 users, that mention a β-blocker, and manually identified 2332 (45.6%) tweets, posted by 1195 (51.1%) of the users, that self-report taking the β-blocker. We were able to estimate the date of the prenatal time period for 356 pregnancies among 334 (27.9%) of these 1195 users. Among these 356 pregnancies, we identified 257 (72.2%) during which the β-blocker was or may have been taken. We manually verified an adverse pregnancy outcome—preterm birth, NICU admission, low birth weight, birth defects, or miscarriage—for 38 (14.8%) of these 257 pregnancies. We manually verified a gestational age ≥37 weeks for 198 (90.4%) and a birth weight ≥5 pounds and 8 ounces for 50 (22.8%) of the 219 pregnancies for which we did not identify an adverse pregnancy outcome.

CONCLUSIONS

Our ability to detect pregnancy outcomes for Twitter users who posted tweets reporting that they took or may have taken a β-blocker during pregnancy suggests that Twitter can be a complementary resource for cohort studies of drug safety in pregnancy.
Implementation of a Novel Concept of Emergency Department Management: e-Boss (Preprint)
Authors: Schmutz Thomas , Habchi Khaled , Le Terrier Christophe , Favre-Kruit Catherine , Stengel Patricia , Guechi Youcef , Ribordy Vincent
Published: June 2022

UNSTRUCTURED

Hospital-based emergency services are frequently criticized worldwide for their management, which can lead to a decrease in staff motivation, with a potential impact on patient safety. This article describes how harnessing the power of social networks can facilitate the management of emergency department teams. Beyond teaching, promoting emergency medicine and recruiting health professionals, these tools can unite employees around a virtual leader and help develop a true service culture. The concept of management through social networks is a novel manner to reach out to staff and should be further explored for use in the health care context.
Teachers’ Practices in Curriculum and Instruction in a Science High School Amidst the Covid-19 Pandemic
Authors: P. Bacosa Dennis , G. Caballes Dennis
Published: June 2022

The disruptions caused by the Covid-19 Pandemic do not excuse science schools from continuing to provide holistic quality education to their learners. This study determined teachers' practices in the Curriculum and instruction as part of School-Based Management Level-3 of a public science high school. The descriptive-correlation quantitative research design and data triangulation were employed. The teachers were on average age of 32.90 years, 75% of the respondents were female, the average years in service of the teachers is eight years, and the majority are Teachers I-III, about 93.8% of the respondents. About 18.8% of the respondents were full-fledged in their Master's Program. Results of the study showed that teachers' overall level of practice in Curriculum and instruction was denoted as highly practiced. Correlational analyses revealed a significant relationship between the highest educational attainment and general practices of teachers in Curriculum and instructions (r=0.478,p=0.002<0.05). A significant relationship between the provision for the development needs of learners and the Review, improvement, and contextualization of assessment tools for teaching and learning as teachers' practices in the Curriculum and Instruction was also presented (r=0.449,p=0.010<0.05). A significant relationship between the regular collaboration of the learning system and the Review, improvement, and contextualization of assessment tools for teaching and learning (r=0.430,p=0.014< 0.05) was also significant.
IoT Based Distribution Transformer Health Monitoring System
Authors: Ramdham Mayur
Published: June 2022

Abstract: This paper is about acquiring real time status of transformer. Transformer plays an important role in power system so, it is essential to monitor its condition for uninterrupted operation of any distribution network. This paper presents an IoT (Internet of Things) based health monitoring system, in this paper NodeMcu has been selected as the processor for transmitting the data sense by sensors, while Thingspeak platform has been used for the display of output data. Adoption of IoT technique in transformer may help for continuity of power supply. This low-cost system can be installed in the transformer to get monitored remotely, which not only determine health condition but also to assist in predicting the life span as well.
IoT Based Coal Mine Tracking and Worker Safety Emergency Alert
Authors: Sameer Mohammad
Published: June 2022

Abstract: Due to global warming and climate change, there are now difficult conditions in the coal mining industry. Automation in the field of coal mine-shaft is in fact necessary to reduce costs and boost profitability while also improving product quality, and it will also reduce diggers' efforts. Mining is both necessary for the manufacture of goods, infrastructure, and services that improve people's lives and one of the world's most dangerous trades. The need for coal as a source of energy is always high and significant. However, hundreds of people have died in mining accidents around the world, and working in the earth poses a variety of security and health risks. Underground miners in some nations lack safety and social protection, and in the event of injury, they may be left to fend for themselves. There are also negative societal consequences, such as displacement and lost income. Among all industries, the mining industry has the greatest rate of occupational mortality. Rock falls, a sagging roof, and a sagging pillar are all common causes of workplace deaths. Underground mines provide a lot of case studies. To deal with all of these tragedies, we need to improve communication technology, which will be used to create an intelligent sensing and warning system. For communication within the mines, RF technology has been adopted. So, utilizing a microcontroller-based circuit on worker safety, we suggest a mining tracking and safety system for the mining business. To detect workers moving throughout the mining site, we deploy RF-based circuitry. The main microcontroller was an ARDUINO UNO. The system employs ATMEGA microcontroller-based RF tracker circuitry to transmit and receive data through the usage of an EM-18 RFID reader module and RFID cards. This aids in the tracking of workers' present locations across the entire mining site. The DHT11 sensor is used to determine the current temperature and humidity. The accelerometer sensor is used to determine whether or not a worker has fallen. MQ2 and MQ135 sensors are used in mines to detect dangerous chemicals and smoke and inform workers. A flame sensor detects a fire in a mine and alerts the workers. Furthermore, safety is the most important aspect of every industry. Safety and security are extremely important in the mining business. Each RFID card circuit includes an emergency button to prevent any form of mishap. When this button is touched, an emergency alert appears. This technology can be used to safeguard the safety of mine workers through the usage of IoT
Rapid Autonomous Vehicle Drifting with Deep Reinforcement Learning
Authors: Samsani Surekha
Published: June 2022

Abstract: Now days all types of vehicles run on road are upgrading to automated self-driving techniques. Drifting is a complicated procedure for autonomous vehicle control which is used for high-speed sideslip cornering. It is difficult to drift a vehicle at a high speed of 80-120 km/hr by using traditional techniques like two-state single-track model and three-state singletrack models, which depend on the knowledge of tire or road forces that are not to be known accurately due to the real-world environmental complexity. Because of these inaccuracies in these parameters there will be poor control performance and may lead to road accidents. In this scenario, this project presents a strong drift control algorithm, which is based on the most recent model-free deep reinforcement learning algorithm called soft actor-critic (SAC). SAC is used to control front-wheel drive (FWD) vehicles to drive at high speed (80– 120 km/h), and to drift through sharp corners quickly and stability which in turn helps to prevent road accidents at the time of drifting. The efficiency of this algorithm is evaluated by conducting experiments on Trajectories dataset taken from Git-Hub repository, which consists of some road maps with reference drift trajectories. The SAC algorithm can also deal with vehicle types with various actual properties, like mass, tyre friction, and so on to show its notable generalization ability.
TECHNIQUE FOR ESTIMATION OF COSTS AND PRICES IN CONTRACTS FOR THE INTERNATIONAL SALE OF GOODS BASED ON INCOTERMS®
Authors: Baena-Rojas Jose Jaime , Cano Jose Alejandro
Published: June 2022

The settlement of costs and prices in international business is an essential aspect of the competitiveness of internationalized companies. In this way, the "International Commercial Terms" (Incoterms)® as rules for the involved parties to a contract of international sale of goods become strategic, not only to define the conditions of delivery of the goods but also to define the value of an export according to the point of delivery within the international physical distribution chain. This study presents a detailed example of the costs derived from an international sale and purchase process, considering different databases published on the Internet, and provides a technique to simulate the value of each Incoterm 2020 rule. The results indicate the estimated prices for an export case from Colombia to the United States for containerized cargo. It is concluded that this technique facilitates the planning of the international sale and purchase, allowing to know the export values for each Incoterm, besides presenting an innovative model adaptable for other goods.
Methodology For Calculating Automotive Oil Radiator
Authors: Parlyuk E. P. , Kurilenko A. V.
Published: June 2022

The paper highlights the relevance of the problem of determining the amount of heat supplied by an internal combustion engine to a liquid cooling system when creating typical series of unified heat exchangers for tractor and combine engines (power units). A properly designed cooling system further guarantees the maintenance of the optimal thermal mode for the engine operation. A methodology for calculating the coolant characteristics of the cooling system was proposed in order to prevent possible problems related to increased parts wear, early loss of oil lubricating properties, the engine (individual units) and rubbing parts overheating, a decrease in engine power and a deterioration in the quality of the fuel-air mixture entering the cylinders.

Research purpose To develop a methodology for calculating the amount of heat to be dissipated by the oil radiators of a liquid cooling system (lubrication system) being exposed to various load and engine speed modes.

Materials and methods It was proposed to determine the amount of heat to be dissipated by the liquid-oil heat exchanger of the engine lube oil cooling system.

Results and discussion The calculation method for oil radiators presents the calculation of the heat obtained by oil during the operation of 37-110 kilowatts automotive engines. The heat-dissipating ability of the oil surface is determined. A parameter taking into account the oil radiator heat flow is identified. The graphs of the oil surface and heat flux dependence on the engine power are presented.

Conclusions The method for calculating the temperature and dynamic characteristics of the automotive engine cooling system has been developed. It makes it possible to carry out research on the radiator thermal and technical characteristics in various operating modes of machines and coolants of systems, various heat exchanger structural materials (metal, polymer), with an error of 1.5-8.0 percent.
An improved quantum-inspired algorithm for linear regression
Authors: Gilyén András , Song Zhao , Tang Ewin
Published: June 2022

We give a classical algorithm for linear regression analogous to the quantum matrix inversion algorithm [Harrow, Hassidim, and Lloyd, Physical Review Letters'09] for low-rank matrices [Wossnig, Zhao, and Prakash, Physical Review Letters'18], when the input matrix A is stored in a data structure applicable for QRAM-based state preparation.Namely, suppose we are given an A∈Cm×n with minimum non-zero singular value σ which supports certain efficient ℓ2-norm importance sampling queries, along with a b∈Cm. Then, for some x∈Cn satisfying ‖x–A+b‖≤ε‖A+b‖, we can output a measurement of |x⟩ in the computational basis and output an entry of x with classical algorithms that run in O~(‖A‖F6‖A‖6σ12ε4) and O~(‖A‖F6‖A‖2σ8ε4) time, respectively. This improves on previous "quantum-inspired" algorithms in this line of research by at least a factor of ‖A‖16σ16ε2 [Chia, Gilyén, Li, Lin, Tang, and Wang, STOC'20]. As a consequence, we show that quantum computers can achieve at most a factor-of-12 speedup for linear regression in this QRAM data structure setting and related settings. Our work applies techniques from sketching algorithms and optimization to the quantum-inspired literature. Unlike earlier works, this is a promising avenue that could lead to feasible implementations of classical regression in a quantum-inspired settings, for comparison against future quantum computers.
Toma de decisiones para la gestión territorial de la seguridad ciudadana: Caso de los comandos de Departamento de Policía Santander y Policía Metropolitana de Bucaramanga
Authors: Pedraza Uribe Luisa Fernanda , Villamizar Moreno Artur Oswaldo
Published: June 2022

Este documento presenta una aproximación al bucle decisional policial con sus características y atributos. Presta especial atención al asesoramiento para la toma de decisiones policiales e indaga sobre los niveles de Gestión Decisional Policial –GDP–. Se presentan los resultados de un estudio exploratorio y cualitativo que corresponde a una fase de la investigación “Gestión Decisional Policial”. Por otro lado, se aplicó el método de sistematización de experiencias y la entrevista semiestructurada como técnica de recolección; de igual forma, se empleó la observación no participante para complementar la visión de los entrevistados. De esta manera, se realizaron veinte entrevistas semiestructuradas a comandantes policiales que integran la pirámide de responsabilidades en la ejecución del Modelo Nacional de Vigilancia Comunitaria por Cuadrantes –MNVCC–. El resultado principal de la investigación es que la GDP compromete a los policías indistintamente de la posición jerárquica en la que se encuentren y obedece a un modelo implícito no declarado. Se concluye la necesidad de construir una visión conjunta sobre la toma de decisiones policiales mediante el estudio de otras unidades policiales para mejorar la propia práctica.
Modernización normativa de la seguridad en Santa Fe, Argentina
Authors: Navarro Urquiza Pablo Emiliano , Oddone Martina Virginia
Published: June 2022

En el presente trabajo analizamos una política pública: el Plan de Modernización Normativa del sistema de seguridad pública de la provincia de Santa Fe, Argentina, llevada adelante a lo largo del año 2020. En este sentido, abordamos la reforma policial en Santa Fe mediante la caracterización del proceso político decisional y el análisis técnico de la formulación y la implementación de dicha política. Además, llevamos a cabo una evaluación preliminar de la política. Asimismo, prestamos particular atención a la política escogida en tanto respuesta estatal a un problema específico y, por otro lado, analizamos cómo fue definido el problema y cuáles fueron las causas identificadas por las autoridades gubernamentales. En definitiva, abordamos la instrumentación de los tres proyectos de ley, así como también los aspectos previos que afectaron al proceso de dicha política. Las fuentes de información son, principalmente, documentos oficiales, entre los que se encuentran los tres proyectos de ley, así como también una colección oficial publicada por el Ministerio de Seguridad de Santa Fe denominada Documentos Institucionales, los cuales pasan revista al estado de situación del sistema policial y de seguridad pública provincial y, también, al compendio normativo que conforma dicho sistema.