bluuebunny/crossref_metadata_2025 huggingface dataset:
Geminivirus C4 proteins inhibit GA signaling via prevention of NbGAI degradation, to promote viral infection and symptom development in N. benthamiana
Authors: Li Pengbai , Guo Liuming , Lang Xinyuan , Li Mingjun , Wu Gentu , Wu Rui , Wang Lyuxin , Zhao Meisheng , Qing Ling
Published: April 2022

The phytohormone gibberellin (GA) is a vital plant signaling molecule that regulates plant growth and defense against abiotic and biotic stresses. To date, the molecular mechanism of the plant responses to viral infection mediated by GA is still undetermined. DELLA is a repressor of GA signaling and is recognized by the F-box protein, a component of the SCFSLY1/GID2 complex. The recognized DELLA is degraded by the ubiquitin-26S proteasome, leading to the activation of GA signaling. Here, we report that ageratum leaf curl Sichuan virus (ALCScV)-infected N. benthamiana plants showed dwarfing symptoms and abnormal flower development. The infection by ALCScV significantly altered the expression of GA pathway-related genes and decreased the content of endogenous GA in N. benthamiana. Furthermore, ALCScV-encoded C4 protein interacts with the DELLA protein NbGAI and interferes with the interaction between NbGAI and NbGID2 to prevent the degradation of NbGAI, leading to inhibition of the GA signaling pathway. Silencing of NbGAI or exogenous GA3 treatment significantly reduces viral accumulation and disease symptoms in N. benthamiana plants. The same results were obtained from experiments with the C4 protein encoded by tobacco curly shoot virus (TbCSV). Therefore, we propose a novel mechanism by which geminivirus C4 proteins control viral infection and disease symptom development by interfering with the GA signaling pathway.
Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi
Authors: Airs Paul M. , Vaccaro Kathy , Gallo Kendra J. , Dinguirard Nathalie , Heimark Zachary W. , Wheeler Nicolas J. , He Jiaye , Weiss Kurt R. , Schroeder Nathan E. , Huisken Jan , Zamanian Mostafa
Published: April 2022

Lymphatic filariasis (LF) is a chronic debilitating neglected tropical disease (NTD) caused by mosquito-transmitted nematodes that afflicts over 60 million people. Control of LF relies on routine mass drug administration with antiparasitics that clear circulating larval parasites but are ineffective against adults. The development of effective adulticides is hampered by a poor understanding of the processes and tissues driving parasite survival in the host. The adult filariae head region contains essential tissues that control parasite feeding, sensory, secretory, and reproductive behaviors, which express promising molecular substrates for the development of antifilarial drugs, vaccines, and diagnostics. We have adapted spatial transcriptomic approaches to map gene expression patterns across these prioritized but historically intractable head tissues. Spatial and tissue-resolved data reveal distinct biases in the origins of known drug targets and secreted antigens. These data were used to identify potential new drug and vaccine targets, including putative hidden antigens expressed in the alimentary canal, and to spatially associate receptor subunits belonging to druggable families. Spatial transcriptomic approaches provide a powerful resource to aid gene function inference and seed antiparasitic discovery pipelines across helminths of relevance to human and animal health.
EDUCAÇÃO E CONSTRUÇÃO DE CIDADANIA
Authors: Rosa Borges Rebeka Cristina , Souza Tabosa Freitas Rita de Cássia
Published: April 2022

Hannah Arendt dedica a sua produção teórica à reflexão sobre o cenário de crises que envolvem o mundo. A seara educacional, recorte teórico principal ao qual se dedica o presente estudo, apresenta-se, no contexto pós-moderno, de forma a estar em contato direto com as crises existente no cenário político, sendo esta crise educacional agravada, ainda, pela ascensão de movimentos neoconservadores na estrutura política brasileira. Nesse sentido, o objetivo geral ao qual se dedica a presente pesquisa perfaz em analisar em que medida o avanço de ações políticas autoritárias ocasionam a perda da função da escola frente à construção da cidadania sob a ótica da crise da educação no Brasil. O trabalho utiliza da abordagem qualitativa de dados, bem como os fenômenos são analisados a partir do método hipotético-dedutivo. O instrumento de coleta de dados foi demarcado pela análise e interpretação de produções científicas arendtiana e pelo uso da pesquisa de caráter bibliográfica, descritiva e exploratória. O arcabouço teórico configura o uso da técnica de análise de conteúdo. O uso da literatura arendtiana como estrutura básica para permite que a análise, de forma interdisciplinar, as áreas da Filosofia, Educação e o Direito. O olhar direcional ao exercício da pluralidade humana a partir das vivências no ambiente de transição, conceituado como o espaço escolar, faz com que possa perceber a ligação entre a ascensão de políticas com inclinação autoritárias e as crises na tradição, cultura, autoridade e do pensar.
DIÁLOGO ENTRE ARTES VISUAIS E DIREITO
Authors: Lopes Carina , Alves Nunes dos Santos Lauer
Published: April 2022

As relações humanas após momentos importantes como a Segunda Guerra mundial têm se mostrado cada vez mais transformadas e flexíveis, gerando grandes impactos na vida social, um exemplo disso é o âmbito e conceito de família. Verifica-se que em tempos mais remotos as relações familiares eram mais duradouras, seja pelo âmbito legal, ou seja, pelo âmbito costumeiro e isso pode ser percebido nas obras de Artes. Com o passar dos anos percebe-se uma liquidez maior das ações humanas que vislumbram uma mudança de visão social transformadora e que acaba refletindo no conceito de família, instituição social sólida. Isso também pode ser percebido no âmbito das artes, evidenciando isso nas diversas obras de arte que compõem o universo social. Desta forma, busca-se analisar a evolução do conceito de família retratado a partir de pinturas e do retrato significativo da arte em trabalhos de artistas nacionais e internacionais. O resultado da pesquisa deve possibilitar a construção de uma linha comparativa da evolução do conceito de família decorrente da evolução social e dos aspectos sociais e legais, buscando perceber se ocorreu uma liquidez do conceito de família ou se embora com evoluções esta continua permanecendo como a instituição sólida de primórdios sociais.
Refugee Integration between a Rock and a Hard Place: Challenges and Possibilities of Local Integration as a Durable Solution for Eritrean and Somali Refugees in Ethiopia
Authors:   Wolkite University, Mena Wogene Berhanu
Published: April 2022

This study examines the challenges and possibilities of local integration for urban refugees by comparing two refugee groups (Eritreans and Somalis) in Addis Ababa. A qualitative research methodology was employed and semistructured interviews with refugees and host communities as well as key informant interviews with the Administration of Refugees and Returnees Affairs (ARRA) and local authorities were conducted. In addition, focus group discussions (FGDs) with refugees and host communities of the study areas were held. The respondents for both interviews and FGDs were purposively selected. The historical and ongoing relations between Ethiopia and the refugee producing countries, a structural factor, impacted not only the country's policy direction towards the refugees but also the refugees and hosts perceptions of local integration. The study revealed that Somali refugees are more integrated in the host communities than Eritrean refugees in the respective areas despite the cultural compatibility of the latter because of the interplay of structural, refugee and host community related factors.
Building Belonging through Art with Young Migrants Living in Care in South Africa
Authors:   Coventry University, Shahrokh Thea , Treves Giulia ,   Lawrence House Child and Youth Care Centre
Published: April 2022

As young people with migration experiences build their lives in new contexts, their connectedness to who they are, to other people, to place and to culture underpin whether and how a sense of belonging is built in their lives. Belonging as a concept matters in young lives as it is underpinned by feelings of acceptance, inclusion and self determination. The realization of belonging can have important implications for young people's wellbeing and development. This paper shares the barriers to belonging for young migrants in South Africa, and how the pain of past experiences, and the exclusions they are navigating in the present constrain their sense of agency, impacting self worth and relationship formation. We share how a child and youth care center in Cape Town specializing in supporting young migrants and young people with experiences of trauma, innovated with a group of young women through participatory arts-based methods towards building belonging. We found that layering multiple arts methods can support young people to connect to their cultural roots and personal relationships, re-build trust, reimagine their identities as part of a collective and challenge power relations around gender, nationality and generation. We found that building belonging should be seen as a continuous learning process, that builds young people's reflective capacities to understand self and others and to make sense of the interaction between past, present and future. In turn, belonging provides an important conceptual tool for youth-led, context-specific approaches to working with young migrants, including on youth transitions.
Remittances and Economic Growth: Evidence from Ethiopia, Kenya, and Uganda
Authors:   Tshwane University of Technology, Zerihun Mulatu F
Published: April 2022

The purpose of this study is to analyze the possible effect of international remittances on the economic growth in three selected economies of Intergovernmental Authority on Development (IGAD) member countries, namely, Ethiopia, Kenya, and Uganda. Remittance inflows have emerged as a key link between human mobility and development. However, empirical findings on the nexus between remittances and economic growth are either conflicting or at most mixed. This paper explores the effects of remittances from international migration inflows on the economic growth of three IGAD member countries. The study uses quantitative analysis that encompasses the above-mentioned countries using the World Bank's annual data from 1990 to 2017. The novelty of this study is that it uses different approaches to solicit the short-run and the long-run nexus between economic growth and remittance flow. The pooled estimation result from fully modified least squares (FMOLS) shows that the logarithm of remittances impacts the dependent variable, economic growth, positively but not statistically significant. The Kao panel residual cointegration test shows that the null hypothesis is not sufficiently supported by the data. There is a statistically significant long-run relationship between the variables in the series.
La importancia de la familia en el aprendizaje de los niños
Authors: Jurado García Esteban , Yarpaz Espinoza Liceth Camila
Published: April 2022

Este artículo científico tiene como finalidad dar a conocer, desde una visión constructiva, la importancia de la familia como agente educador en los procesos de enseñanza y aprendizaje; su rol en el actuar, en la puesta en escena de los valores, actitudes y habilidades que los niños adquieren y en su desenvolvimiento en las instituciones educativas. Se busca que el lector conozca, desde otra perspectiva, cómo la influencia de la familia hace parte del desarrollo integral y autónomo de los niños y las niñas, en aras de garantizar que cada acción influya significativamente en su desarrollo y se vea reflejado en su diario vivir.
“Es que cada niño es diferente”: el saber de las maestras sobre los niños
Authors: Fandiño Cubillos Graciela , Gonzalez Kathy , Galeano Jose Ignacio , Pardo Alberto
Published: April 2022

Esta investigación buscó caracterizar el saber docente sobre niños y niñas (menores de 6 años) de maestras de jardines infantiles y colegios públicos de Bogotá. El estudio fue de corte constructivo-cualitativo, el análisis de contenido inductivo, y las categorías emergieron de la lectura de los investigadores. El análisis muestra cómo las perspectivas de las maestras tienen estructuras particulares e idiosincráticas pero comparables. Las categorías construidas fueron las siguientes: desde dónde hablan las maestras de los niños y de qué hablan cuando describen a los niños. Los hallazgos y conclusiones muestran la relación entre categorías a partir de los discursos de las maestras, que se estructuran en referencias contextuales, la visión de ser maestra y de ser niño, el reconocimiento de la singularidad de cada niño, la presencia de contenidos, la manera en que ellas cualifican y significan sus descripciones y apreciaciones sobre el ser infantil y cómo proyectan y dan cuenta de vivencias compartidas con los niños.
Remuneração docente no Brasil sob a ótica da disputa pelo fundo público (2008–2020)
Authors: Fernandes Maria Dilneia Espíndola , Bassi Marcos Edgar , Rolim Rosana Maria Gemaque
Published: April 2022

O artigo analisa a remuneração docente da educação básica brasileira, como constituinte do fundo público. O fundo público, por sua natureza e características, coloca-se em disputa por diferentes setores sociais: se para a reprodução e acumulação do capital ou se para a reprodução da força de trabalho. No caso específico da força de trabalho docente, durante a maior parte do período de 2008 a 2020, sua reprodução teve ganhos favoráveis, por meio do fundo público. Contudo, tal fato se reverteu, pela promoção da austeridade fiscal instaurada com a aprovação da Emenda Constitucional nº 95/2016. Trabalha-se, no texto, com dados nacionais, publicados em sítios oficiais e institutos do Governo Federal, e documentos produzidos nas esferas da sociedade civil organizada, em diálogo com as demais áreas do conhecimento. Constata-se que a disputa pelo fundo público entre as classes sociais brasileiras reposiciona precariamente a reprodução da força de trabalho docente, em termos remuneratórios e de contrato de trabalho, com graves implicações para o direito e a qualidade da educação básica.
A educação como investimento público: Necessidade política, debate econômico e proposições institucionais
Authors: Pinto Élida Graziane , Ximenes Salomão Barros , Carvalho André Roncaglia
Published: April 2022

O artigo recupera, apresenta e discute uma proposta alternativa de financiamento à educação pública no Brasil: seu enquadramento como investimento público mediante a reclassificação da natureza jurídica de todo o gasto em manutenção e desenvolvimento do ensino, para que seja financiável, se necessário, mediante operações de crédito para fins da “regra de ouro”, a que se refere o art. 167, III da Constituição de 1988. Faz isso em perspectiva multidisciplinar ao explorar as interfaces entre a construção das políticas de planejamento e financiamento educacional no país, o debate econômico sobre desenvolvimento e capital humano no Estado Social e a análise do desenho jurídico-institucional dos gastos em educação, na forma em que são enquadrados pelo direito financeiro. Ao final, são feitas proposições ao debate sobre a necessidade de reestruturar os pressupostos que hoje balizam as possibilidades e limites de financiamento sustentado das políticas educacionais no País e, consequentemente, de realização do direito fundamental à educação de qualidade para todos.
The Impact of Electrical Energy Consumption on the Payback Period of a Rooftop Grid-Connected Photovoltaic System: A case Study from Vietnam
Authors: Ngo Xuan Cuong , Do Nhu Y
Published: April 2022

Recently, the use of small-scale grid-connected photovoltaic (GCPV) systems for households has been growing in Vietnam. The installation of a rooftop GCPV system provides many benefits to households, such as lowering monthly electricity bills, reducing absorbed heat of the building, and creating additional income by penetrating electric power to the grid. However, the technical issues of the payback period is complicated and requires a lot of considerations. The main goal of this study is to develop a computational model and investigate the effect of electrical energy consumption on the payback period of rooftop GCPV systems. A case study is used in this study to create a model of a rooftop GCPV system for households in north-central Vietnam under feed-in tariff (FiT) schemes. The results show that the investment rate and electrical energy consumption of the installed household have a strong influence on the payback period of the GCPV system. In the case of the lowest investment rate of 666.4 USD/kWp, the fastest payback period is 43 months for households consuming all of the generating energy of the GCPV system, and the longest payback period is 131 months for households that do not use electricity, implying that all of the generating energy of the GCPV system is connected and sold to the distribution grid. The research findings will actively assist in calculating the installed capacity suitable for households in order to have the most suitable payback period while also assisting policymakers in the future in setting a reasonable rate of feed-in tariff for rooftop GCPV systems
Behavior of Soil Condition under Theoretical and Practical Approach: A State of the Art Review
Authors: Bhorhari Raghavendra , . Yusuf , Vishwakarma Arvind
Published: April 2022

This article presents a brief review on soil condition of different location 8 strata with respect to the theoretical and practical aspect. It is found that the properties of the soil are important aspect to role part in the design aspect of foundation 8 superstructure constructed above on it. The below substructure part analysis such as bore hole, SSI, SBC 8 other effects. The review concluded that the soil profile is found to distinct properties in all aspect such as index properties, colours, strength etc. It also vary with theoretical approach adopted for the calculation so it is important to study and analyse between theoretical and practical approach and co-relation between them.
Gestures Controlled Home Automation using Deep Learning: A Review
Authors: Bankar1 Amruta S. , Harale Avinash D. , Karande Kailash J.
Published: April 2022

This paper presents the review of the studies carried out on the application using computer vision for hand gesture recognition. Hand gestures can be used to operate the electronic devices. Therefore, it is very much essential to review on the scientific studies whose aim is to develop a technique to achieve more precise and faster sign language recognition system for plain and cluttered backgrounds with different humans to help speech and hearing impaired in their life, robot control, human–computer interaction (HCI), home automation and medical fields. The objective of this paper is to give an overall literature review of the work done related to identify the current technology and methodology used in hand gesture recognition as well as home automation system. This paper mainly describes various images or vision based sign language recognition system comprising pre-processing, feature extraction and classification. The system conversion of sign language to text. The recognized text can be sent to the control model. The gesture based automation communicates directly with control model to control home appliances.
Concerted action of berberine in the porcine intestinal epithelial model IPEC‐J2: Effects on tight junctions and apoptosis
Authors: Cornelius Valeria , Droessler Linda , Boehm Elisa , Amasheh Salah
Published: April 2022

The plant alkaloid berberine has been shown to have many beneficial effects on human health. This has led to its use as a treatment for various cancer types, obesity, and diabetes. Moreover, a described barrier‐strengthening effect in human cancer cell lines indicates that it might be useful for the treatment of inflammatory bowel disease. Detailed information regarding its effects on intestinal epithelium remains limited. In our current study, we describe the impact of berberine on a non‐transformed porcine small intestinal epithelial cell model, IPEC‐J2. Incubation of IPEC‐J2 monolayers with berberine revealed dose‐ and time‐dependent effects on barrier properties. A viability assay confirmed the specific effect of berberine on the apoptotic pathway, paralleled by the internalization of the sealing tight‐junction (TJ) proteins claudin‐1, claudin‐3, and occludin within 6 h. Hence, the barrier function of the cells was reduced, as shown by the reduced transepithelial electrical resistance and the increased [3H]‐D‐Mannitol flux. A decrease of claudin‐1, claudin‐3, and occludin expression was also observed after 24 h, whereas ZO‐1 expression was not significantly changed. These data indicate an early effect on both cell viability and barrier integrity, followed by a general effect on TJ architecture. The intracellular co‐localization of claudin‐1 and occludin or claudin‐3 and occludin points to an initial induction of apoptosis accompanied by the internalization of sealing TJ proteins. Although barrier strengthening has been reported in cancerogenic epithelial models, our results show a barrier‐weakening action, which represents a new aspect of the effect of berberine on epithelia. These results agree with the known toxic potential of plant alkaloids in general and show that berberine is also capable of exerting adverse effects in the intestinal epithelium.
Binge eating disorder during COVID-19
Authors: Mumtaz Sara , Farhat Syeda Mehpara , Saeed Rida Fatima , Younis Sidra , Ali Mahwish
Published: April 2022

With the onset of coronavirus disease in December 2019, the normal routine and lifestyle of the humans has adversely affected all over the world. This change in lifestyle not only increased the level of stress and anxiety, but also badly modified the eating habits during the lockdown period. This increased the rate of binge eating disorder in people who were already immune-compromised. This rapid communication aims to develop awareness among people to stay calm during this pandemic and eat healthy.
Mobility of Top Income Taxpayers in Response to Regional Differences in Personal Taxes: Evidence from Spain
Authors: López-Laborda Julio , Rodrigo Fernando
Published: April 2022

The study empirically tests whether regional differences in personal taxes (Personal Income Tax, Wealth Tax, and Inheritance and Gift tax) have had some influence on the decision of the richest Spanish taxpayers to change their residence. The estimates use the Personal Income Tax (IRPF) Panel database provided by the Ministry of Public Finance. The study offers evidence that regional tax differences affect the decision to change residence of the top income taxpayers and also that this decision is also affected by other attractiveness and opportunity factors offered by the regions, and by certain characteristics of the individuals. However, the marginal effects are very slight, except for the coefficient of the variable showing regional differences in IRPF: If the difference between average regional IRPF rates increases by 10 percentage points in favour of the other regions, the probability of a top 1% taxpayer changing its residence increases by 11.2 percentage points. The study also documents the importance of the Community of Madrid in the relocation decisions of rich taxpayers. Finally, the study finds that the behaviour of taxpayers aged 65 years and over in the top 1% does not seem very different from that of all taxpayers in the same income bracket.
Developing a questionnaire for diabetes mellitus type 2 risk effects and precondition factors – multivariate statistical paths
Authors: Nedyalkova Miroslava , Romanova Julia , Naneva Ludmila , Simeonov Vasil
Published: April 2022

The primary purpose of the present study is to summarize and explain the results of a questionnaire about diabetes mellitus type 2 (DMT2) endangered individuals. The 275 participants (age between 21 and 76 years) answered 18 questions related to the possible danger of DMT2 disorder. Multivariate statistical methods – cluster analysis, factor and principal components analysis applied for the survey analysis. The final goal was to detect similarity patterns between the variables of interest (questions), to reveal hidden factors regulating the data structure and susceptibility to DMT2 among the participants or between them, to elucidate the health status of the different groups and the similarities within the groups. It was found that five hidden factors regulate the data structure, which are conditionally named “declined general health status”; “metabolic syndrome factor”; “smoking, alcohol abuse and stress factor”; “heredity and sex impact”; “healthy food” impact. The participants could be divided into four similarity patterns, each with probably different susceptibility to DMT2. Thus, the results of the questionnaire could be of use for prophylactic purposes.
Das sei ferne!
Authors: Kakridis Yannis
Published: April 2022

The dialogical exchange with a fictitious opponent is the main feature of the so-called Cynic-Stoic Diatribe, a mode of exposition that was developed in Ancient Greek and Roman literature. In Greek diatribe, the formula μὴ γένοιτο ‘far from it’ is used to reject the views of the fictitious opponent. The Apostle Paul, whose writings exhibit many features of diatribe, makes ample use of this formula. In the Church Slavonic translation of the New Testament, μὴ γένοιτο appears as да не бѫдетъ or (less often) не бѫди. In the Fourth (Athonitic) redaction of this translation, да не бѫдетъ is used throughout. This text served as the basis for the first printed edition of the second part of the New Testament, the Apostolos (Vilna, 1525). The editor, Franciscus Skorina, tried – albeit in a very inconsistent manner – to modernize the text. He either retained the diatribal formula да не бѫдетъ or replaced it by то не естъ, да не будеть сеє при насъ, никако, да не будеть то, да не будемъ, никакоже and николиже. This diversity arose independently of the Czech Bible of Venice (1506), which was the second main source of Skorina’s Bible translations. The use of the 1st person plural (при насъ, да не будемъ) reflects similar forms in the preceding context of Paul’s Letter to the Romans.
Magyarországról származó utazók a 19. századi Indiában
Authors: Bangha Imre
Published: April 2022

For centuries, India has been of special importance to Hungarians due to its accessibility and cultural richness. As early as before the twentieth century, many Hungarians or travellers of other nationalities from historical Hungary visited the subcontinent. In this study, along with drawing attention to some lesser-known travellers, I will examine the social backgrounds, the motives and interests of all the people who we know at present reached India before the twentieth century.
The Role of Magical Thinking, Sensitivity, and Thought Content in Thought-Action Fusion
Authors: Fite Robert E. , Magee Joshua C.
Published: April 2022

Introduction: Cognitive models of obsessive-compulsive disorder (OCD) posit that maladaptive beliefs about intrusive thinking contribute to the disorder's development and maintenance. However, the findings concerning one notable belief, thought-action fusion (TAF), have been inconsistent. Current conceptualizations of TAF may conflate constructs such as magical thinking, sensitivity, and thought content that are already the subject of informative, interdisciplinary literatures. Methods: To tease apart these constructs, adult participants (N = 249) reported their trait levels of sensitivity and magical thinking, and were randomly assigned to engage with an intrusive thought in one of three content areas. We hypothesized that morality-related content would lead to heightened maladaptive outcomes, but only in combination with higher trait levels of sensitivity and magical thinking. Results: Results indicated that morality-related content, along with sensitivity to morality, played more of a prominent role in maladaptive outcomes, with magical thinking being implicated in general outcomes like worry. Discussion: These findings suggest that the link between TAF and maladaptive outcomes may depend on which TAF elements are present for an individual. Sensitivity, in tandem with other TAF elements (e.g., morality-related content, magical thinking) is predictive of divergent outcomes (e.g., worrying, urges to neutralize) and thus may be an important target of future interventions aimed at reducing TAF, worrying, and/or OC symptoms.
Lawrence Welk
Authors: Rogers Bradley
Published: April 2022

This essay explores the musical politics of Lawrence Welk, the bandleader whose television show was a mainstay of American popular culture from 1955 through 1982. I argue that Welk’s interests in gender, family, and work—both philosophically and musically—reveal the maestro as a harbinger of late twentieth-century political and cultural discourse. I focus on Welk’s transition (around 1970–1973) from his trademark champagne sound—which featured woodwinds and ornamentation—to a “Big Band Sound,” which emphasized the unison open brass. Around the same time, he stopped referring to his ensemble as “The Champagne Music Makers” and began calling them his “Musical Family.” I argue that his “Big Band Sound” was in fact a musical articulation of his “Musical Family”—and that Welk instituted both of these changes in response to what he perceived as the decline of American work ethic and sexual morality. I suggest that Welk’s champagne sound, which once signified whiteness, was now feminized and seen as emblematic of indolent hedonism. He sought to purge this feminization—and this aversion to work—precisely by adopting the more “masculine” brassy sound. I also show how he deployed family acts—and his managerial scheme of a “Family Plan”—to promote his conservative ideals about work and the family. In this way, Welk provided the sound of the Nixonian “silent majority.” I conclude by noting how three elements of Welk’s show—his fondness for mistakes, the emphasis on visual spectacle, and the erratic temporality of syndication—provide the potential for a counter-reading of his efforts.
Rhyme, Reason, Rogue
Authors: Adeduntan Ayo
Published: April 2022

Popular culture is often othered in conservative theses as inferior and [or because it is] foreign. Scholarship and views on popular music in Nigeria have been sometimes inattentive to the extent that the popular musical forms have gone to entrench themselves as recognizable local forms. This article compares older popular forms that are now canonized—such as jùjú and highlife—with Nigerian Yoruba hip hop to show the peculiar historical factors that justify the latter’s cultural heterodoxy. The dominant hip hop morality that emerged is defiantly divergent from the earlier stress on formal education and legitimate industry. Importantly, hip hop performance in Yoruba has evolved a protocol of social criticism that first presents itself as acquiescent and/or reprobate. Also, existing conceptualization of hip hop acts as hidden [or even public] transcripts is complicated by the novel strategy of mimicry now found in the Yoruba form.
Functions of Expressive Timing in Hip-Hop Flow
Authors: Duinker Ben
Published: April 2022

Expressive timing in hip-hop flow concerns the practice whereby an MC (rapper) inflects their flow rhythms on a minuscule scale not easily representable with standard musical notation—how far “ahead” or “behind” the beat they rap. Mitchell Ohriner (2019) positions expressive timing as an integral part of hip-hop flow and discusses it in detail. This paper complements his work by surveying flow timing across the broader hip-hop genre.

Three broad practices of expressive timing in flow are identified. Swung timing subdivides the tactus unequally, similar to a common jazz drum timekeeping pattern. Lagging timing refers to the patterned delay of flow rhythm in relation to the underlying instrumental or sampled beat. And conversational timing pertains to flow performances that resemble rhythmic patterns idiomatic of spoken language. Theoretical and notational concepts developed by Fernando Benadon (2006, 2009) and Ohriner (2019) are used to illustrate the extent to which a flow performance involves these approaches to expressive timing, and propose analytical methods for these approaches that highlight their functional and rhetorical appeal. Expressive timing is investigated in light of Signifyin(g) in African American music (Samuel Floyd Jr., 2002), groove-based expressive microtiming (Vijay Iyer, 2002), Afrocentric models of rhetoric (Ronald Jackson, 1995), and narrativity.
Development of InDel markers and fingerprinting of bitter gourd (Momordica charantia) based on whole genome re-sequencing
Authors: Su Liwen , Huang Xiaochun , Wu Wenting , Lv Haixuan , Cheng Zhikui , Ma Lianlian , Gou Jiquan , Chen Yong , Wang Peng , Liu Zhengguo
Published: April 2022

Bitter gourd (Momordica charantia) is cultivated widely as a vegetable and herbal medicine in many Asian and African countries. Two varieties ('LS-5' and 'LS-22') were re-sequenced by next-generation sequencing technology, and a set of InDel markers was developed. The genome
of 'Dali-11' was the reference genome. Exactly 59098 and 73683 InDel loci were identified in 'LS-5' and 'LS-22', respectively. To verify the reliability of this set of InDel markers, 220 pairs of InDel primers were designed and synthesised. Primers were preliminarily detected by 8% polyacrylamide
gel electrophoresis. Thereafter, 15 pairs of polymorphic primers were selected and employed to construct the DNA fingerprint of 27 bitter gourd varieties. The purity of five hybrid seed lots, 'Zhongyu', 'Heiyu', 'Lvzhu', 'Shunliu 3' and 'Shunliu 8', was determined using the specific primers.
In this study, a batch of InDel primers with high polymorphism potential was developed based on resequencing. These primers can effectively distinguish some bitter gourd varieties. Therefore, this set of reliable and accurate InDel markers can provide a richer marker source for bitter gourd
variety identification and seed purity determination.
Method for the evaluation of mitigation measures for soil loss compensation based on cadstral data
Authors: Zupan Marko
Published: April 2022

Agricultural soils are a non-renewable natural resource, and substitute land can only be acquired at the cost of losing other resources, such as forest ecosystems or restoring degraded land. An alternative is to improve soils of poorer quality through topsoil application and meliorative measures, thus increasing the production potential of existing agricultural land. In this paper, we present the measure of topsoil addition for maintaining production potential and the method of calculating the agricultural land equivalent (EKZ) to evaluate the impact of topsoil addition. The EKZ method was tested on hydromorphic and automorphic soils and on fragmented and consolidated agricultural land. The examples of EKZ calculation presented show that the addition of fertile topsoil can be an appropriate measure to mitigate the effects of soil sealing on the loss of production potential of agricultural land but not to the same extent for all soil types. The effect is greater when we improve low-quality soils such as gley soils or shallow soils with coarse particles. The EKZ method is objective, taking into account the original extent, land rating value, shape, and fragmentation of soils, as well as soils after topsoil has been added. The method also supports the rational use of the removed fertile soil and thus the conservation of a non- renewable natural resource.
Revisiting growth hormone nadir cut-offs for remission in patients with acromegaly
Authors: Kim Jiwon , Hwang Yoon-a , Park Yae Won , Moon Ju Hyung , Kim Eui Hyun , Hong Jae Won , Lee Eun Jig , Ku Cheol Ryong
Published: April 2022

Objective

Over the past decade, the growth hormone (GH) nadir cut-off during the oral glucose tolerance test for remission in patients with acromegaly was changed from 0.4 to 1.0 μg/L due to the limited use of ultrasensitive detection kits to measure GH levels. However, the optimal cut-off level for GH nadir remains unclear. This retrospective study aimed to investigate the association between different GH nadir cut-offs and prognosis in patients with acromegaly.

Design and methods

A total of 285 patients with acromegaly with a glucose-suppressed GH nadir <1 μg/L at 3–6 months after trans-sphenoidal adenomectomy were divided into two groups according to the glucose-suppressed GH nadir levels at 3–6 months post-operatively (group A: <0.4 μg/L; group B: 0.4–1.0 μg/L). GH levels were measured using an ultrasensitive IRMA. The clinical, hormonal, metabolic, and neuroradiological data of the two groups were compared.

Results

Female sex, as well as confirmed macroadenomas, was significantly overrepresented in group B. The 5-year rate of patients who achieved nadir GH < 1.0 μg/L and age- and sex-matched normal IGF-1 was significantly higher in group A than that in group B. However, there was no significant difference between the two groups in metabolic parameters at 12 months post-operatively.

Conclusion

Different GH nadir cut-offs were associated with different 5-year rates of patients who achieved nadir GH <1.0 μg/L and age- and sex-matched normal IGF-1, suggesting that a strict GH nadir threshold of 0.4 μg/L correlates better with remission.
Overlapping consensus in the space of public morality (on John Rawls’s political constructivism
Authors: Rogozha Mariya
Published: April 2022

The article is focused on the overlapping consensus model in the space of public morality and possibilities of its practical realization for the development of public consent. In his search for reliable arrangement of public unity John Rawls defines comprehensive moral doctrines and political doctrines as beliefs within private and public spheres, respectively. Overlapping consensus provides public consent in the public space (concerning political doctrines), beyond beliefs of private sphere (comprehensive moral doctrines). Moral values of overlapping consensus form the sphere of public morality, effective in definite historic democratic society. Rawls called it a well-ordered society. Definite historic character of a well-ordered society is predetermined by corresponding background culture. The latter can be implied as the experience of citizenship, conditioned by peculiarities of social institutions of Modernity. It is immediate immanent axiological accompaniment of the public life, background one concerning explicit ethical normative programs and strategies of acting by individuals in public life, directed on optimization of public interaction. Moral values within overlapping consensus are minimalistic (because of their set able to unite all members of a society is the basic one for all of them, irrespectively to their comprehensive moral doctrines, i.e. poor in content, laconic one), contextual (module/ flexible, relevant to public spiritual requests, transforming during the search for integrity minimum) and universal in their imperative power. Overlapping consensus makes impossible transformation of any comprehensive moral doctrine into the regulative idea of public life and set formal horizontal social interaction, which is corrected in real time mode.
Silver-Russell sendromunda sanal gerçeklik uygulamalarının etkileri: olgu raporu
Authors: DENGIZ Aziz , BASKAN Emre , KIZMAZ Erhan
Published: April 2022

Silver-Russell Sendromu, büyüme ve gelişim geriliğine neden olan nadir görülen bir hastalıktır. Bu çalışmanın amacı hipotonik Silver-Russell Sendromu’lu bir olguda sanal gerçeklik uygulamalarının etkilerinin incelenmesidir. Dokuz yaşındaki erkek hasta sık düşme, yürümede güçlük ve üst ekstremite fonksiyonlarını yerine getirmede zorluk şikayetiyle tedaviye alınmıştır. Hastanın dengesi Pediatrik Berg Denge Ölçeği ile, kaba motor fonksiyonları Kaba Motor Fonksiyon Ölçütü ile, fonksiyonel bağımsızlık düzeyi Çocuklar İçin Fonksiyonel Bağımsızlık Ölçeği ile, kas kuvveti Gross Kas Testi ile değerlendirilmiştir. Hasta 2 ay boyunca haftada 2 seans 45 dakika X Box 360 Kinect Sanal Gerçeklik Uygulaması ile rehabilitasyona dahil edilmiştir. Hastanın vücut ağırlığının 22 kg olduğu boy uzunluğunun 120 cm olduğu tespit edilmiştir. Pediatrik Berg Denge Ölçeği, Kaba Motor Fonksiyon Ölçütü, Fonksiyonel Bağımsızlık Ölçeği skorları tedavi öncesi-tedavi sonrası sırasıyla, 34-43, 213 (%79,54) – 240 (%90,9), 97-110 olarak ölçülmüştür. Kas kuvveti üst ve alt ekstremitede ilk değerlendirmede orta, tedavi sonrası iyi olarak tespit edilmiştir. Olgumuzun tedavi sonuçları Silver-Russell sendromlu çocuklara sanal gerçeklik uygulamalarının denge, fonksiyonel bağımsızlık düzeyi, kaba motor fonksiyonu ve kas kuvveti üzerine etkili olabileceğini göstermiştir. Bu alanda yapılacak geniş örneklemli çalışmalarla sanal gerçeklik uygulamalarının etkinliği daha net bir şekilde ortaya konacaktır.
La crisis del pensamiento urbano normalizado, un llamado a su ruptura a través de la creatividad
Authors: Peláez Víctor Antonio , Mounirou-Diallo Mamadou
Published: April 2022

Este artículo discute la conferencia: "Pensar la ciudad del mañana es un gran desafío paradójico” extrapolándola al contexto latinoamericano y africano. Para lo cual, primero se exhibe la riqueza del intercambio de ideas entre los autores, resaltando también el llamado del profesor Bourdin a buscar nuevas herramientas de pensamiento urbano. Luego, se apela a la ruptura de la hegemonía de las ideas mostrando la incidencia del pensamiento normalizado en los citados continentes, revelando también las tres restricciones que nos impiden pensar la ciudad del futuro.Consecutivamente, se desarrollan algunas propuestas para ir más allá de la normalización que se refieren al uso de la imaginación; finalmente, se presentan algunas conclusiones que apelan a un cambio inminente en el rumbo del pensamiento académico, haciendo un llamado a los investigadores para que asuman el riesgo público de emitir criterios.
Évaluation de la coherence du processus de mise en oeuvre du projet pilote de smart meters dans le secteur residentiel à Diar El Bahri (Blida) en Algérie
Authors: Ouahiba Belhocine , Kahina A Djiar , Wissam Benaouicha
Published: April 2022

Le secteur énergétique en Algérie a subi d'énormes transformations au cours des deux dernières décennies. L'un des changements majeurs qui ont été opéré est lié, particulièrement, à l'introduction des technologies de l'information et de la communication (TICs) dans la maitrise de la consommation énergétique. Parmi les réalisations les plus récentes, un projet pilote relatif à l’introduction de smart meters a été lancé dans le secteur résidentiel à Diar El Bahri situé dans la wilaya de Blida, à 47 km au sud-ouest de la capitale d’Algérie, Alger. Il s’agit de la première expérience en la matière dans le pays, marquant ainsi une étape majeure vers le développement de la Smart Grid.Malgré la volonté de mise en place d’un cadre communicationnel bidirectionnel de la maitrise de la consommation énergétique, le projet en question, qui était initialement programmé pour une période de (02) deux ans, n’a duré que (06) six mois. Par ailleurs, le nombre de foyers qui étaient censés bénéficier d’un raccordement aux smart meters n’a pas été respecté.L’objectif de cette recherche est de comprendre précisément le processus de mise en place dudit dispositif. Il s’agit d’effectuer une première évaluation, jamais conduite auparavant, de l’expérience Algérienne en matière de recours aux technologies de l’information et de la communication dans le cadre de la modernisation de la gestion et de maitrise énergétique. Cet article fait partie d'une recherche originale plus large qui vise à explorer les différentes voies à travers lesquelles les TICs peuvent être développées dans le secteur de l’habitat en Algérie de manière à accroître l'efficacité énergétique et créer des territoires numériques.
Emergencias y fatalidades mineras subterráneas en Colombia
Authors: Galvis Ocampo Yuly Tatiana , Oviedo-Rubiano Nicolás Enrique , Franco Sepúlveda Giovanni
Published: April 2022

Durante 2019 en Colombia, el 1,9% de los títulos mineros correspondientes a gran minera, aportaron el 91% de las regalías; en contraste con esta cifra económica, el 90,4% de los títulos mineros clasificados como mediana y pequeña minería, aportaron el 63% de las fatalidades (el 37% restante fue aportado por minería ilegal). Desde 2005 la autoridad minera se encuentra recopilando información sobre emergencias y fatalidades mineras, lideró la actualización al reglamento de seguridad en las labores mineras subterráneas, fortaleció la fiscalización minera, entre otros aspectos y la tendencia al aumento de este fenómeno no ha disminuido. Por lo tanto, se realiza un análisis descriptivo de esta base de datos (emergencias y fatalidades mineras) en R, un software para el procesamiento y análisis estadístico, con el fin de identificar las variables de mayor incidencia. Para finalmente proponer tres modelos estadísticos que nos permitan predecir el fenómeno de estudio en un periodo de tiempo, generando insumos para enriquecer la discusión en torno a la seguridad minera del país.
El reto para la belleza y el habitar en la ciudad global del futuro
Authors: Mansur Garda Juan Carlos
Published: April 2022

Este artículo reflexiona sobre el lugar que tendrá la belleza en las ciudades del futuro a partir de los desafíos que enfrentan las ciudades globales. Éstas han degradado la calidad de vida de sus habitantes como consecuencia de planear la vida y las ciudades con una visión racionalista, y que en el caso de la ciudad capitalista llegan al extremo de manipular la vivencia estética, haciéndola un medio de consumo. Dos grandes retos enfrentarán las ciudades del futuro: por un lado vencer la inercia que impone la actual edificación y diseñar las ciudades a partir de la propuesta fenomenológica del espacio, que pone en el centro del diseño a la persona, y en segundo lugar, que se supere la visión racionalista a cambio de una visión que logre integrar trabajo, belleza y vida.
Señales débiles del futuro de las ciudades
Authors: González Arellano Salomón , Morales Zaragoza Nora A.
Published: April 2022

En las últimas décadas los estudios del futuro han desarrollado un cuerpo teórico y metodológico importante en el que destaca el problema de las “señales débiles”. Además, existe un interés creciente en analizar escenarios futuros de las ciudades por parte de urbanistas, académicos y agencias de gobierno. El objetivo de este artículo es revisar la noción de “señal débil” en el marco de las ciudades. Abordamos tres casos de estudio a partir de un análisis retrospectivo para trazar las señales débiles de innovaciones urbanas en el sector del transporte, trabajo y alimentación. Concluimos que los procesos transformativos de las ciudades son antecedidos por señales débiles, que al inicio son poco visibles y difusas, que al incorporarse eventualmente con otras señales contextuales y tendencias se pueden asociar a futuros escenarios. Los estudios de caso analizados permiten identificar que estamos ante una serie de transformaciones enmarcadas por la economía colaborativa que configuran el trabajo, el transporte y la alimentación entre otras esferas de la vida urbana.
How to quote Ethiopian authors in linguistic publications
Authors: Meyer Ronny , Treis Yvonne
Published: April 2022

As the patronymic Ethiopian names do not match the widespread GIVEN NAME – FAMILY NAME pattern of the Western world, the names of Ethiopian authors are often quoted inconsistently and inappropriately by scholars in the field of linguistic typology and historical-comparative linguistics. After a brief introduction into the Ethiopian naming conventions and a summary of recurrent issues in quoting Ethiopian authors in scientific publications, we propose a number of general citation rules that would help overcome these issues and do justice to the Ethiopian naming conventions. The rules are offered as an addendum to the Generic Style Rules for Linguistics. Finally, the article demonstrates how reference management software can be manipulated so that it correctly applies the Ethiopian naming conventions.