bluuebunny/crossref_metadata_2025 huggingface dataset:
La Actividad Parlamentaria de enero a junio de 2005 (VII Legislatura)
Authors: Nieto Lozano Ángeles , Prada Barrio María Isabel , García Álvarez Manuel José
Published: November 2023

Sumario: I. INTRODUCCIÓN.—II. COMPOSICIÓN DE LOS ÓRGANOS DE LA CÁMARA.—III. EL FUNCIONAMIENTO DE LOS ÓRGANOS DE LA CÁMARA.—3.1. El Pleno de la Asamblea de Madrid.—3.2. Las Comisiones de la Asamblea de Madrid.—3.3. La Diputación Permanente de la Asamblea de Madrid.—3.4. La Mesa de la Asamblea de Madrid.—3.5. La Junta de Portavoces de la Asamblea de Madrid.—IV. LA ACTIVIDAD LEGISLATIVA DE LA CÁMARA.—4.1. Relación de Leyes aprobadas.—V. RESUMEN DE LA ACTIVIDAD PARLAMENTARIA (enero/junio 2005).—5.1. Cuadros resumen de actividad parlamentaria.—5.2. Gráficos estadísticos.
AHUMADA RUIZ, Marian (2005). La Jurisdicción Constitucional en Europa. Navarra: Thomson Civitas
Authors: Sánchez Ferro Susana
Published: November 2023

Recensión de la obra: AHUMADA RUIZ, Marian (2005). La Jurisdicción Constitucional en Europa. Navarra: Thomson Civitas.
Irreelegibilidad, inelegibilidad e incompatibilidad parlamentaria: Los artículos 23 y 70 de la Constitución y las razones políticas de la prohibición de ser reelegido
Authors: García Eloy
Published: November 2023

Sumario: I. PLANTEAMIENTO GENERAL DE LA IRREELEGIBILIDAD.—II. INELEGIBILIDAD Y CONSTITUCIÓN ESPAÑOLA DE 1978: LOS ARTÍCULOS 23 Y 70 DE LA CONSTITUCIÓN.—2.1. La inelegibilidad.—2.2. Incapacitación e inhabilitación judicial.—2.3. La incompatibilidad parlamentaria.—III. LA IRREELEGIBILIDAD COMO SUPUESTO CONCRETO DE INELEGIBILIDAD.
Aportación al debate sobre el futuro de la Monarquía Parlamentaria
Authors: Álvarez Vélez M.ª Isabel , Alcón Yustas Fuencisla
Published: November 2023

Sumario: I. INTRODUCCIÓN.—II. LA CONSTITUCIONALIZACIÓN DE LA MONARQUÍA EN 1978.—2.1. La Monarquía en el proceso constituyente.—2.2. El significado de la Monarquía y las funciones constitucionales del Rey.—III. LA CORONA Y LAS CORTES.—IV. CARACTERIZACIÓN DE LA MONARQUÍA EN LOS ESTADOS EUROPEOS.—V. A MODO DE CONCLUSIÓN: LA OPCIÓN MONÁRQUICA EN EL SIGLO XXI.
La conciliación de la vida familiar y laboral, un compromiso y una oportunidad para la modernización de la Administración Pública
Authors: Murillo Ulloa Ernesto
Published: November 2023

Reflexión sobre la conciliación de la vida familiar y laboral, un compromiso y una oportunidad para la modernización de la Administración Pública.
CARMONA CUENCA, Encarna (2005). La crisis del recurso de amparo. La protección de los derechos fundamentales entre el Poder Judicial y el Tribunal Constitucional. Madrid: Universidad de Alcalá, Servicio de Publicaciones
Authors: Del Pino Carazo Ana
Published: November 2023

Recensión de la obra: CARMONA CUENCA, Encarna (2005). La crisis del recurso de amparo. La protección de los derechos fundamentales entre el Poder Judicial y el Tribunal Constitucional. Madrid: Universidad de Alcalá, Servicio de Publicaciones.
Position of impacted canines and lateral incisors, and factors associated with unerupted canines
Authors:   Czech Orthodontic Society, Kolaříková Markéta , Černochová Pavlína
Published: November 2023

Aim: The aim is to determine the impact of unerupted canine position on the position of adjacent teeth as well as the relationship of the severity of canine impaction and position, and associated factors of the impaction. Material and method: From CBCTs of the patients treated between 2015 and 2020 at the Department of Orthodontics of St.Anne’s University Hospital 39 scans with unilateral impacted upper canine were selected. There were 25 palatally impacted canines, 14 vestibularly impacted canines. The parameters measurements were carried out with Invivo6 software after setting of the reference planes. Results: Factors associated with canines impaction were proved, such as shift of the midline towards the affected side (by 0.56–0.68 mm), higher incidence of peg shaped lateral incisor (I2) in palatally impacted canines, narrower palate on the side of impacted canine (by 1 mm in palatally and 2 mm in vestibularly impacted canine). In vestibularly impacted canines lateral incisors (I2) were significantly more distally inclined (by 10.3°), in palatally impacted canines lateral incisors (I2) were distorotated by 14.1°and retruded by 7.2°. In vestibularly impacted canines the roots of I2 were shortened by almost 2 mm, in palatally impacted canines by 1 mm. On the side of impacted canines we found higher incidence of bent roots (51.3%) and hooks (12.8%); I2 bent roots were more frequent on the side of palatally impacted canines (32%). Conclusion: The study findings could help in early diagnostics – either clinical or radiological – of impacted upper permanent canines, and in adopting the best strategy of treatment. Disturbed development of impacted canines (shorter length, bent root) calls for early detection and timely orthodontic treatment of the impaction.
Evaluating the relationship between IFA remuneration and advice quality
Authors: Sindelar Jiri , Budinsky Petr
Published: November 2023

This article deals with the interaction between commission remuneration of independent financial advisers and selected sales factors, including the quality of advice. Utilizing data on investment transactions and a linear model with mixed effects, we have found that the link between commission and quality of the subsequent recommendation is not homogeneous, and advice-bias potential is present only in a limited range of organizational environments, connected mainly to the flat-structure business model. On the other hand, arbitrage between different product classes was found to create a biasing potential across almost all types of firms, creating potential for market systemic risk. Finally, the effect of information provided was proved to be significant only to a very limited extent. © 2017 Academy of Financial Services.
La evaluación según Ley 070 ASEP en la educación secundaria
Authors: Mollo-Torrico Juan Pablo , Mendoza Montemayor Rodrigo
Published: November 2023

La educación en Bolivia viene desarrollando planificaciones estratégicas, dando cumplimiento a las diferentes reformas y modelos educativos. Este trabajo tuvo como objetivo analizar la evaluación integral según la Ley 070 ASEP en el proceso de enseñanza y aprendizaje en el aula y su relación en la calidad educativa; así mismo identificamos principales dificultades que se encuentran en la evaluación integral y las carencias que presenta esta ley respecto a la evaluación de conocimientos en el aula. El estudio piloto tuvo una metodología descriptiva y cuenta con una muestra de 55 estudiantes de 3ro y 4to de educación secundaria del Municipio de Colcapirhua. Los hallazgos encontrados nos muestran que los estudiantes con un (56,4%), les gusta aprender de manera visual, mediada por la observación de dicha temática avanzada, se identificó dificultades al momento de evaluar, lo que genera en el estudiante un tipo de estrés que lo desmotiva en clases, además. Apoyados por los recursos como ser los libros (65,5%) y apuntes (32,7%) fortalecen aún más el momento cuando llega su evaluación.
Didácticas de la literatura intercultural en la educación secundaria
Authors: Montiel Lugo Katherine
Published: November 2023

Es fundamental analizar el sistema educativo, el contexto escolar, los planes curriculares y la exploración de enfoques y estrategias pedagógicas que aborden los procesos de selección de la literatura en la dinámica de la enseñanza y el aprendizaje en las instituciones educativas. El objetivo fue abordar las didácticas de la literatura intercultural, los fundamentos teórico-metodológicos que sustentan las didácticas actuales de la literatura e interculturalidad y conceptualiza la literatura intercultural desde las didácticas y prácticas pedagógicas. Metodológicamente es una investigación cualitativa con uso de análisis de contenido. Los hallazgos apuntaron hacia que la literatura plantea a profesores y estudiantes cuestiones como la selección y la evaluación crítica de textos, la relación de la escritura contemporánea con nuestra vida en relación con escritores y textos de otros países y culturas. Como conclusiones, urge la necesidad de un cambio de paradigma teórico y metodológico que diversifique los textos literarios, posibles modos de lectura y amplíe el umbral de géneros y textos literarios a discutir en el aula, lo que fomenta la conexión de nuevos tipos de lectura que amplíen las perspectivas y puntos de vista sobre la vida y la cultura.
Expresiones de conciencia sobre el cambio en la praxis docente
Authors: Salas Julio , Martínez Marvis
Published: November 2023

El artículo propone interpretar las expresiones de conciencia de los docentes de Ciencias Naturales, con respecto a su praxis docente al emplear un Conocimiento Pedagógico de Contenido para enseñar Naturaleza de la Ciencia. Metodológicamente está enmarcado en el paradigma interpretativo que empleó la metodología de investigación acción para recabar la información y procurar cambios. Los resultados fueron examinados siguiendo los postulados fenomenológicos Husserlianos para así poder comprender las expresiones de conciencia que emergían en un grupo de docentes de Ciencias Naturales del Instituto Pedagógico de Caracas (IPC) acerca de su praxis docente. Por ende, se infiere que la percepción que un docente tiene sobre su praxis docente resulta determinante sobre su accionar pedagógico. De ésta, depende el grado de conciencia que el sujeto desarrolla y, en consecuencia, ese marco fenoménico que se reconstruye permanentemente, influye en las creencias, actitudes, intenciones y acciones que el profesional de la docencia desarrolla en su praxis docente. A manera de conclusión se pudo comprender que los cambios ocurren después de mucha resistencia para salir de la zona de confort, pero que una vez que ocurren la conciencia del docente y el ambiente de clase mejoran significativamente.
Desarrollo Laboral: Profesionales de Movimiento y Corporalidad
Authors: Morales Rincón Camilo
Published: November 2023

El objetivo de este artículo fue identificar las características generales del quehacer de los profesionales del sector del movimiento y la corporalidad. En cuanto a la metodología, se elaboró bajo el enfoque cuantitativo, el tipo de investigación se orienta hacia lo descriptivo, el diseño fue no experimental. La población estuvo representada por 500 personas, la técnica de recolección de información fue una encuesta estructurada en dos secciones, las cuales fueron pertinentes para este estudio, el instrumento fue un cuestionario estructurado. La validez del instrumento fue realizada mediante la valoración de cinco (05) expertos en el área de estudio. Se realizó la respectiva interpretación y análisis para presentar los resultados. Se evidencia como resultado la similitud entre lo obtenido en las encuestas y lo desarrollado por los autores base consultados, encontrando una diversidad en las titulaciones y perfiles ocupacionales en el sector del movimiento y la corporalidad. Se concluye que, que es relevante el generar una caracterización permanente de los mismos con la finalidad de encontrar la interrelación entre la formación, los intereses del profesional y las necesidades del sector.
Estudio Clínico Epidemiológico de la Fibrosis Quística en el Instituto Nacional de Salud del Niño, Lima 2002-2011
Authors: Torres Vela Daniel , Del Castillo Barrientos Hernán , Flores Fernández Carol , Zavaleta Pesantes Amparo
Published: November 2023

Introducción: La Fibrosis Quística (FQ) es una enfermedad autosómica recesiva que se manifiesta principalmente por su compromiso a nivel pulmonar y digestivo. En Perú, la prevalencia de FQ es desconocida, así como las características clínicas y epidemiológicas de la enfermedad.

Objetivos: Determinar las características clínicas y epidemiológicas de la FQ en el Instituto Nacional de Salud del Niño en el periodo comprendido entre los años 2008 y 2011.

Materiales y Métodos: Se realizó una investigación clínica epidemiológica con tipo de diseño observacional, retrospectivo y descriptivo. Se seleccionaron casos de pacientes del Instituto Nacional de Salud del Niño que en sus historias clínicas consignaban el diagnóstico de la enfermedad, en el periodo comprendido entre enero del 2002 y diciembre del 2011.

Resultados: Se consignaron 37 casos que cumplieron los criterios de inclusión según el consenso de la Fundación Americana de FQ. Las edades de diagnóstico fluctuaron desde un mes hasta 16 años, siendo el 51,4% mujeres. Las características clínicas principales fueron predominantemente respiratorias y digestivas, se encontró que el 94,6% de los pacientes presentó síntomas respiratorios agudos o crónicos y el 54,1% esteatorrea.

Conclusiones: En todos los pacientes se encontró enfermedad sinopulmomar crónica, de los cuales el 75,7% presentó tos crónica productiva. Las anomalías gastrointestinales se presentaron en el 81,1% de los pacientes, encontrándose falla en el crecimiento en todos ellos. La complicación más frecuente fue la neumonía en un 59,5%. El agente patógeno más frecuente en las vías respiratorias fue Staphylococcus aureus en el 51,4%, seguido de Pseudomonas aeruginosa en el 48,6%.
Tipos de Retracción de Prepucio en Niños en el Hospital Belén de Trujillo, Perú
Authors: Alfaro Zelada José Miguel , Alfaro Ríos Segundo José , Lázaro Rodríguez Herminia
Published: November 2023

Introducción: El prepucio es la parte de la piel que recubre el glande. Al nacer, el recién nacido tiene un prepucio estrecho, adherente y largo, con punta angosta que sobrepasa el extremo distal del glande.

Objetivos: Determinar los tipos de retracción del prepucio según la edad en niños menores de 15 años.

Materiales y métodos: Se realizó el examen clínico a 360 niños divididos en 9 grupos de 40 cada uno. Fueron atendidos en el Departamento de Pediatría del Hospital Belén de Trujillo. Se evaluó el grado de retracción del prepucio aplicando la clasificación de Kayaba, según grupo etario.

Resultados: Muestran que los tipos de retracción del prepucio I y II son más frecuentes en recién nacidos (45% y 52.5%) y niños menores de 6 meses (35% y 32.5%), el tipo V no se encuentra en menores de 6 meses (0% en ambos grupos). En los niños de 11 a 15 años predomina el tipo V (75%) y no se encuentran los tipos I y II (0%).

Conclusiones: A mayor edad aumenta la retracción del prepucio. Los tipos de retracción del prepucio I y II predominan en los recién nacidos y niños menores de 1 año de edad y los tipos IV y V predominan en los niños entre 11 y 15 años.
Malrotation in the Adult, a Forgotten Etiology of Partial Gut Obstruction: A Report of Two Cases
Authors: Cabanilla-Manuntag Ma. Corazon , Cruz Jan Paolo , Manlubatan Sofia Isabel , Lopez Marc Paul
Published: November 2023

Ninety percent of cases of malrotation have shown signs and symptoms of intestinal obstruction by the first year of life. It is thus an often-overlooked etiology in adult patients. Evidence-based recommendations are also limited because of the paucity of cases. This paper discusses the two cases of malrotation from diagnosis to surgical management at a tertiary academic hospital. Both are previously well adult male patients with virgin abdomen who presented with vomiting and signs of intestinal obstruction. During medical decompression, CT scan with triple contrast clinched the diagnosis of malrotation for which Ladd’s procedure was done, with no operative complications. The authors’ experience and previous literature support early decompression, imaging, and surgery for all cases of malrotation regardless of severity of symptoms. Key words: intestinal malrotation, bowel obstruction, Ladd’s procedure
Sigmoid Squamous Cell Carcinoma Presenting as a Bladder Mass: A Case Report
Authors: Lopez Marc Paul , Manlubatan Sofia Isabel , Dela Victoria Czarlo
Published: November 2023

Primary squamous cell carcinoma (SCC) of the colon and rectum is a rare malignancy, with an incidence of less than 1 in 1,000 diagnosed colorectal cancers. This is a case of a 59-year-old male who presented with a three-month history of urinary symptoms. Work-up, however, revealed a locally-advanced, partially-obstructing primary sigmoid squamous cell carcinoma with extension to the urinary bladder. He subsequently underwent a proximal bowel diversion after extensive carcinomatosis was discovered on diagnostic laparoscopy. Colon SCC represents less than 0.5% of all colorectal tumors, and its incidence is estimated to be 0.1%. Clinically, it presents with similar signs and symptoms as colorectal adenocarcinoma. No standardized management approach has been established yet. A multidisciplinary team approach is essential in dealing with such cases. Keen attention and further investigation are warranted to clearly define the management approach to achieve better outcomes. Key words: colorectal cancer, squamous cell cancer, urinary bladder, rectum
Estrogen and Progesterone Hormone Receptor Status in Pre-menopausal and Post-menopausal Women with Invasive Ductal Carcinoma in a Private Tertiary Hospital in Cebu City, Philippines: A Retrospective Study
Authors: Rocacurva Remille April Cecilia , Siguan Stephen Sixto
Published: November 2023

Objective: This study was conducted to determine the difference of hormone receptor status between pre-menopausal and postmenopausal women diagnosed with invasive ductal carcinoma in the local setting. Methods: This retrospective descriptive study used data gathered from chart review of premenopausal and postmenopausal female patients diagnosed with invasive ductal carcinoma by tissue biopsy and underwent determination of hormone receptor status (estrogen and progesterone receptor) by immunohistochemical staining (ICA) using biopsy samples taken from June 2016 to December 2019 at Cebu Velez General Hospital, Cebu City. The significance of the difference in the hormone receptor status with menopausal status was analyzed using Fisher’s exact test. Results: Comparing the two groups, 25 (60%) of the pre-menopausal women and 37 (73%) of the post-menopausal women were determined as hormone sensitive, while 17 (40%) pre-menopausal women and 14 (27%) post-menopausal women were hormone resistant. The Fisher’s exact test did not detect a statistically significant difference in the hormone receptor status of pre-menopausal and post-menopausal breast cancer patients. Conclusion: There is no significant difference on the hormonal receptor status among pre-menopausal and post-menopausal women diagnosed with invasive ductal carcinoma. Thus, the need for hormone receptor status determination in these patients should be emphasized to aid in proper diagnosis, prognostication, and treatment planning. Key words: Hormone receptor status, menopausal status, invasive ductal carcinoma, immunohistochemical staining
Knowledge, Attitude and Practice of Filipino Surgeons Regarding Clinical Practice Guidelines on Thyroid Nodules and Malignancy: A PCS-PSGS -PAHNSI Collaborative Study
Authors: Tabangay-Lim Ida Marie , Mercado Maria Elizabeth , Cucueco Maria Cheryl , de Dios Alfred Philip , Gasataya Venerio
Published: November 2023

Rationale: In 2008, the Philippine College of Surgeons in collaboration with the Philippine Society of General Surgeons and the Philippine Academy of Head and Neck Surgeons, Inc. had published Evidence-based Clinical Practice Guidelines (CPG) on the Diagnosis and Management of Thyroid Nodules. This was followed by an update in 2013 with a focus on important diagnostic and therapeutic management issues concerning thyroid malignancy. The objective of this study was to assess knowledge gaps and behavioral patterns among users with respect to these CPGs. Methods: A validated 30 item survey assessing knowledge of, attitudes towards, and adherence to the recommendations of different Evidence based Clinical Practice Guidelines was administered to general surgery residents, PSGS fellows, and otorhinolaryngology residents and consultants performing thyroidectomies. Results: There were 343 assessable forms. Of the respondents, 276 (80.47%) were general surgeons, 33 (9.62%) were otorhinolaryngologists. There were 66 (19.24%) consultants, and 277 (80.76%) residents. Otorhinolaryngologists were less aware of the local CPGs than their GS counterparts. GS Residents, compared to their consultants, were more aware of the American Thyroid Association guidelines than the local guidelines. Among all respondents, the local guidelines had about equal preference for usage as the American Thyroid Association guidelines. There were no statistically significant differences on the level of knowledge and attitudes among the respondents. Conclusions: The level of awareness about the PCS Thyroid Guidelines needs to be improved. The dissemination process needs to be reviewed and ensure that all stakeholders will be reached. Key words: thyroid, clinical practice guidelines
Avaliação ultrasonográfica dos preenchedores e bioestimuladores em diferentes aparelhos de ultrassonografia e com diferentes frequências
Authors: Câmara Cláudia Borges Fontan , Cardoso Daniele , Rezende Juliana Paulos de , Zattar Luciana Carmen , Mota Americo
Published: November 2023

A popularidade do uso de preenchedores e bioestimuladores faciais para o rejuvenescimento e embelezamento da face é um crescente mundial. Em paralelo, o avanço tecnológico na medicina permitiu o desenvolvimento de transdutores de ultrassonografia de alta resolução que vem permitindo a avalição anatômica detalhada das camadas da pele e um novo entendimento da anatomia da face. Com isso tornou-se possível identificar a presença destas substâncias, assim como a localização exata nas camadas da face e suas possíveis complicações.  O objetivo deste estudo é mostrar os diversos aspectos ultrassonográficos dos preenchedores e bioestimuladores faciais mais comumente encontrados na prática clínica, com diferentes transdutores de ultrassonografia.
Parece câncer, mas não é. Tumor desmóide mimetizando malignidade mamária
Authors: Pereira Jamile de Melo Casado , Miranda Ana Clara Araújo , Miranda Beatriz Medicis Maranhão , Pereira Isabel Cristina Areia Lopes , Cantilino Christiane Tine
Published: November 2023

A fibromatose, também conhecida como tumor desmóide, é uma lesão benigna rara de células fusiformes, que pode surgir a partir das estruturas músculo-aponeuróticas que se sobrepõem ao músculo peitoral maior, da cápsula fibrosa do implante de silicone e, mais raramente, no interior do parênquima mamário. Embora a etiologia seja desconhecida, alguns fatores de risco estão associados ao seu desenvolvimento, como trauma, mamoplastia redutora, implante de silicone, síndromes genéticas como a síndrome de Gardner, polipose adenomatosa familiar e esporádica, fibromatose multicêntrica familiar, além do uso de pílulas anticoncepcionais orais e gestação. Os exames de imagem das mamas frequentemente não são específicos para o diagnóstico de fibromatose e podem frequentemente mimetizar carcinoma primário da mama. O objetivo deste estudo é apresentar três casos de mulheres com fibromatose mamária mimetizando carcinoma mamário nos métodos de imagem, incluindo um caso com apresentação radiológica atípica e sem fatores de risco identificáveis. Em conclusão, a fibromatose do tipo desmoide da mama é um tumor fibroblástico incomum e benigno, localmente agressivo, sem potencial metastático. Não possui um fenótipo de imagem específico. Distinguir a fibromatose mamária de tumores malignos de mama apenas por meio de exame físico, história clínica e técnicas de imagem é sempre desafiador, sendo necessária a confirmação histopatológica. Devido à alta tendência à recorrência, o diagnóstico precoce e a excisão local são o tratamento de escolha.
Mimarlık Fakültesi Öğrencilerinin Sürdürülebilirlik Algısının İstatistiksel Yöntemlerle Analizi; Kırklareli Üniversitesi Mimarlık Fakültesi Örneği
Authors: KOPUZ Aysu , MÜLAYİM Ali
Published: November 2023

Sürekli artan dünya nüfusu, toplumların tüketim toplumuna dönüşmesi, ürünlerin eskime sürelerinin azalması (planlı eskitme), ortaya çıkan yeni ihtiyaçları da beraberinde getirmiştir. Bu nedenlerle hammadde ihtiyacının artması, doğal kaynakların azalması, üretim sonucu ortaya çıkan atıklar, küresel ısınma gibi sebeplerle dünyanın ekolojik dengesinin bozulması sonucunda dünya bir yok oluşa doğru gitmektedir. Dünyanın yok oluşunun durdurulamasa bile en azından yavaşlatılabilmesi için sürdürülebilirlik, geri dönüşüm, tasarruf, temiz enerji gibi kavramlar ile ilgili farkındalık oluşturulmasının önemi her geçen gün artmaktadır. Sürdürülebilirliğin temel boyutlarının benimsenmesi ve içselleştirilmesi yoluyla davranışların bu doğrultuda değiştirilmesi, sürdürülebilir bir toplum oluşturulmasında önemli bir basamaktır. Çevreye yapılan her müdahale sonucunda insan ve yaşama mekanları olumsuz yönde etkilenmektedir. Sürdürülebilir bir dünya için insanlar gerek özel yaşamlarında gerekse de mesleki yaşamlarında önlem almaya çalışmalıdırlar.

Bu çalışma, Kırklareli Üniversitesi Mimarlık Fakültesindeki öğrencilerinin sürdürülebilirlik bilgileri ve farkındalıklarını, sürdürülebilirlik eğitimi konularına yaklaşımlarını, sürdürülebilir yaşam doğrultusundaki düşüncelerini ve uygulamalarını ölçmektedir. Bu doğrultuda Mimarlık Fakültesi, Mimarlık Bölümü ile Şehir ve Bölge Planlama Bölümü öğrencilerinin “Sürdürülebilirlik Farkındalığı” adlı anket çalışmasına katılımları sağlanmıştır.

Belirlenen gruba betimsel tarama yöntemi ve 5’li likert ölçeğinde anketler yapılmıştır. Anket sonuçları betimleyici istatistik yöntemi kullanılarak “IBM SPSS Statistics 25” programı ile analiz edilmiş ve yorumlanmıştır. Ki Kare yöntemiyle cinsiyet ve bölümün ifadeler üzerindeki etkisi incelenmiştir. Araştırma sonucunda elde edilen verilerin; birbirleriyle karşılaştırılabilmesi, ilişki kurulabilmesi ve niceliksel olarak ölçülebilmesi için yukarıda sıralanan metodoloji uygulanmıştır. Elde edilen verilere göre; öğrencilerin bireysel sürdürülebilirliğin farkında oldukları, bireysel sürdürülebilirlik uygulamalarında bilinçli olmalarına rağmen bazı gereklilikleri sosyo-ekonomik durumları veya şartların uygun olmaması nedeniyle yerine getiremedikleri sonuçlarına varılmıştır.
Teaching by Example: Evidence of Data Literacy Competencies and Practices in Top Economics Journal Articles
Authors: Marchant Margaret
Published: November 2023

Objective: Data literacy is the ability to describe, evaluate, use, share, and cite data. It is increasingly important for researchers and college students, including in the field of economics. This study explores the prevalence of data literacy competencies in economics articles. Data literacy competencies displayed in journal articles demonstrate what researchers value and provide opportunities to teach students, helping librarians shape data services and instruction.Methods: Based on close reading of economics and data literacy literature, the author developed a protocol of terms relating to data literacy. A stratified random sample of 100 articles was selected from ten top economics journals. Adobe Acrobat’s index search function was used to conduct automated content analysis coding, with additional manual checking for accuracy and data sharing and sources.Results: The economics research articles in the study sample showed strong coverage of terms relating to describing, evaluating, and using data. Sharing and citing data were identified as areas for improvement as only 36% of articles shared data and 40% included terms related to citation. The analysis verifies previous research about the prevalence of commercial data use in business research and adds insight on frequently used open data sources. Conclusions: There are clear data literacy strengths within economics. Librarians have the skills to partner with economics instructors to reinforce strengths and improve gaps to prepare more data literate students.
Joubert Syndrome-Related Disorder: Report of Six Cases and Literature Review
Authors: Mohamed Kareem , Awwad Belal
Published: November 2023

Background: The prevalence of Joubert syndrome in most Arab countries is unknown, yet it has an estimated prevalence of 1/5,000 live births in the United Arab Emirates. Geographic areas where consanguinity represent high percentage (40-60%) of marriages, similar prevalence might be expected.Findings: In Case 1 (Figure 2), we found the neuroimaging features of classic JS in the form of MTS and mild vermian hypoplasia. In Case 2, (Figure 3) the imaging features included the appearance of persistent Blake’s pouch cyst. In Case 3 (Figure 4), we found the additional imaging features of Dandy Walker malformation. Case 4 (Figure 5) revealed classic JS features of the posterior fossa but with partial dysgenesis of the corpus callosum. In Case 5 (Figure 6), we found the unidentified JSRD that would help in recognizing the prognosis and clinical outcome. Case 6 (Figure 7) demonstrated the associated small posterior fossa, dysplastic superior vermis, occipital meninigocele, platybasia and compression of the cervicomedullary junction.Conclusion: First, these cases emphasize the importance of raising the clinical suspicion in this diagnosis in newborns presenting with abnormal respiration. Second, it is essential for the radiologist to look for other posterior fossa anomalies in case of finding an entity before jumping to a certain or specific syndrome. Additionally, follow-up cases of hydrocephalus should be thoroughly searched again for congenital malformations.Limitations: Our main limitation is the lack of genetic study of the presented cases due to outsourcing. That could help better classification of the Joubert syndrome in children.
Opportunities in Multiple Sclerosis Care Partner Research: An Interview
Authors: Finlayson Marcia , Pakenham Kenneth
Published: November 2023

INTRODUCTION

Guest editor Marcia Finlayson, PhD, OT Reg (Ont), OTR, is a professor in the School of Rehabilitation Therapy at Queen’s University in Ontario, Canada. She began her career as a clinical occupational therapist and shifted to a research career focused on generating and sharing knowledge to help people affected by multiple sclerosis (MS) lead healthy, meaningful lives with control over their participation in daily activities, at home and in the community, particularly as they age.

For this special issue on caregiving in MS, she chose to interview Kenneth Pakenham, PhD, emeritus professor of clinical and health psychology at the University of Queensland in Brisbane, Australia. For more than 4 decades, he has investigated the psychological well-being welle-eing of caregivers, including coping mechanisms and innovative interventions to improve their quality of life. His work is dedicated to applying positive health frameworks to chronic illnesses and to empowering caregivers and individuals with MS.

Together, their expertise illuminates the multifaceted challenges and opportunities in MS caregiving research and understanding.
Lignocellulose and Polylactide Fibres in Acoustic Nonwovens and Composite Materials
Authors:   , Seile Arta
Published: November 2023

Within the Thesis, a nonwoven material was made from a mixture of hemp and polylactide fibres using the mechanical needle punching method, from which a composite material was made using the thermopressing method. In parallel, nonwoven and composite materials were developed, where hemp fibres replace flax fibres. The priority in the development of materials was the use of annually renewable resources and environmentally friendly technologies. In the Thesis, the produced materials are compared with each other, both in terms of physico-mechanical properties and in terms of environmental aspects.
Overburdened Ferroptotic Stress Impairs Tooth Morphogenesis
Authors: Wang H.S. , Wang X.F. , Huang L.Y. , Wang C.L. , Yu F.Y. , Ye L.
Published: November 2023

The role of regulated cell death (RCD) in organ development, particularly the impact of non-apoptotic cell death, remains largely uncharted. Ferroptosis, a non-apoptotic cell death pathway known for its iron dependence and lethal lipid peroxidation, is currently being rigorously investigated for its pathological functions. The balance between ferroptotic stress (iron and iron-dependent lipid peroxidation) and ferroptosis supervising pathways (anti-lipid peroxidation systems) serves as the key mechanism regulating the activation of ferroptosis. Comparing to other forms of regulated necrotic cell death (RNCD), ferroptosis is critically related to the metabolism of lipid and iron which are also important in organ development. In our study, we examined the role of ferroptosis in organogenesis using an
ex vivo
tooth germ culture model, investigating the presence and impact of ferroptotic stress on tooth germ development. Our findings revealed that ferroptotic stress increased during tooth development, while the expression of Gpx4, a crucial anti-lipid peroxidation enzyme, also escalated in dental epithelium/mesenchyme cells. The inhibition of ferroptosis was found to partially rescue erastin-impaired tooth morphogenesis. Our results suggest that while ferroptotic stress is present during tooth organogenesis, its effects are efficaciously controlled by the subsequent upregulation of Gpx4. Notably, an overabundance of ferroptotic stress, as induced by erastin, suppresses tooth morphogenesis.
The 14-3-3/spastin pathway coordinates neurite regeneration and recovery of spinal cord injury by targeting microtubule dynamics
Authors: Liu Qiuling , Yang Hua , Luo Jianxian , Peng Cheng , Wang Ke , Zhang Guowei , Ji Zhisheng , Lin Hongsheng
Published: November 2023

Axon regeneration is abortive in the central nervous system following injury. Orchestrating microtubule dynamics has emerged as a promising approach to improve axonal regeneration. The microtubule severing enzyme spastin is essential for axonal development and regeneration through remodeling of microtubule arrangement. To date, however, little is known regarding the mechanisms underlying spastin action in neural regeneration after spinal cord injury. Here, we use glutathione transferase pulldown and immunoprecipitation assays to demonstrate that 14-3-3 interacts with spastin, both
in vivo
and
in vitro,
via spastin Ser233 phosphorylation. Moreover, we show that 14-3-3 protects spastin from degradation by inhibiting the ubiquitination pathway and upregulates the spastin-dependent severing ability. Furthermore, improving the interaction between 14-3-3 and spastin by Fusicoccin (FC-A) promotes neurite outgrowth and regeneration
in vitro
. Western blot and immunofluorescence results revealed that 14-3-3 protein is upregulated in the neuronal compartment after spinal cord injury
in vivo
. In addition, administration of FC-A not only promotes locomotor recovery, but also nerve regeneration following spinal cord injury in both contusion and lateral hemisection models. However, application of spastin inhibitor spastazoline successfully reverses these phenomena. Taken together, these results indicate that 14-3-3 is a molecular switch that regulates spastin protein levels, and 14-3-3/spastin pathway is an important target for regulation of microtubule dynamics for nerve regeneration after spinal cord injury.
Four Individually Identified Paired Dopamine Neurons Signal Taste Punishment in Larval Drosophila
Authors: Weber Denise , Vogt Katrin , Miroschnikow Anton , Pankratz Michael , Thum Andreas S.
Published: November 2023

Dopaminergic neurons (DANs) carry out multiple tasks in the brain, including the transmission of information related to rewards and punishments across various animal species. They are responsible for evaluating sensory input, storing resultant associations as memory, and continuously updating them based on their relevance and reliability. Accurate comprehension of the dopaminergic system’s operation necessitates an understanding of the specific functions mediated by individual DANs. To this end, our research employs
Drosophila
larvae, which possess approximately 12,000 neurons in their brains, of which only around 1% (approximately 120) are DANs.The presynaptic projections to the mushroom body (MB) - a brain region pivotal for associative olfactory learning in insects - are limited to only eight larval dopaminergic neurons. These DANs are further subdivided into two clusters: the primary protocerebral anterior medial cluster (pPAM) comprises four cells, and the dorsolateral 1 cluster (DL1) comprises the remaining four cells. Our findings confirm previous research that demonstrates that the pPAM DANs innervating the MB’s medial lobe encode for a gustatory sugar reward signal. Furthermore, we have identified four DANs in the DL1 cluster - DAN-c1, DAN-d1, DAN-f1, and DAN-g1 - each of which innervates distinct compartments of the MB peduncle, lateral appendix, and vertical lobe. Optogenetic activation of DAN-f1 and DAN-g1 alone suffices to substitute for salt punishment. Furthermore, optogenetic inhibition, calcium imaging results and electron microscopy-based reconstruction of all sensory input circuits to the four DL1 DANs demonstrate that each DAN encodes a different aspect of salt punishment, with DAN-g1 being of central importance.To summarize, our investigation has revealed the existence of a cellular division of labor among larval DANs concerning the transmission of dopaminergic reward (pPAM cluster) and punishment signals (DL1 cluster). Individual DANs in each cluster encode for distinct but partially overlapping aspects of the teaching signal. The striking resemblance in the organizing principle of larval DANs with that of its adult counterpart and the mammalian basal ganglion suggests that there may be a limited number of efficient neural circuit solutions available to address more complex cognitive challenges in nature.
Vehicle target detection method based on improved YOLO V3 network model
Authors: Zhang Qirong , Han Zhong , Zhang Yu
Published: November 2023

For the problem of insufficient small target detection ability of the existing network model, a vehicle target detection method based on the improved YOLO V3 network model is proposed in the article. The improvement of the algorithm model can effectively improve the detection ability of small target vehicles in aerial photography. The optimization and adjustment of the anchor box and the improvement of the network residual module have improved the small target detection effect of the algorithm. Furthermore, the introduction of the rectangular prediction frame with orientation angles into the model of this article can improve the vehicle positioning efficiency of the algorithm, greatly reduce the problem of wrong detection and missed detection of vehicles in the model, and provide ideas for solving related problems. Experiments show that the accuracy rate of the improved algorithm model is 89.3%. Compared to the YOLO V3 algorithm, it is improved by 15.9%. The recall rate is improved by 16%, and the F1 value is also improved by 15.9%, which greatly increased the detection efficiency of aerial vehicles.
Seasonal benthic species composition linked to coastal defense structures (CDS) in Kuala Nerus, Terengganu, Malaysia
Authors: Ibrahim Nur Fazne , Abd Hamid Muzzalifah , Mohd Akhir Mohd Fadzil , Chuan Ong Meng , Wan Talaat Wan Izatul Asma , Idris Izwandy
Published: November 2023

Background

The natural hydrodynamic process of Kuala Nerus, Terengganu, has changed since the extension of Sultan Mahmud Airport runway in 2008. Consequently, severe coastal erosion has occurred in the area, particularly during the northeast monsoon season (NEM). Numerous types of coastal defense structures (CDS) have been constructed to protect the coastline. Despite the loss of esthetic values, the effect of CDS construction on marine organisms in the area remains unknown. Hence, this study aims to assess the ecological aspects of macrobenthic compositions at the CDS area of Kuala Nerus, Terengganu, based on the differences between the southwest (SWM) and northeast (NEM) monsoon seasons.

Methods

Macrobenthos were collected from the sediment in July (SWM) and December 2021 (NEM) using the Ponar grab at 12 substations from five sampling stations.

Results

The density of macrobenthos was higher in SWM (48,190.82 ind./m2) than in NEM (24,504.83 ind./m2), with phylum Mollusca recording the highest species composition (60–99.3%). The macrobenthos species had a low to moderate level of diversity (H’ = 1.4–3.1) with the species were almost evenly distributed (J’ = 0.2–0.8). Windward substations exhibited coarser grain sizes (38.56%–86.84%), whereas landward substations exhibited very fine grain sizes (44.26%–86.70%). The SWM season recorded a higher organic matter content (1.6%–6.33%) than the NEM season (0.4%–3.1%). However, metal concentrations in the surface sediment were within the safe range and permissible limits for both seasons, inferring that the macrobenthos composition was unaffected.

Discussion

This study demonstrated that the CDS associated with the monsoon system has controlled the hydrodynamics and nearshore sedimentary processes in the Kuala Nerus coastal zone, thereby affecting the macrobenthos population, in terms of richness and density. The ecological and energetic effects of the coastal structures in different seasons have resulted in a more significant result, with the SWM exhibiting a higher macrobenthos composition than the NEM.
Immune activity score to assess the prognosis, immunotherapy and chemotherapy response in gastric cancer and experimental validation
Authors: Wu Xuan , Zhou Fengrui , Cheng Boran , Tong Gangling , Chen Minhua , He Lirui , Li Zhu , Yu Shaokang , Wang Shubin , Lin Liping
Published: November 2023

Background

Gastric cancer (GC) is an extremely heterogeneous malignancy with a complex tumor microenvironment (TME) that contributes to unsatisfactory prognosis.

Methods

The overall activity score for assessing the immune activity of GC patients was developed based on cancer immune cycle activity index in the Tracking Tumor Immunophenotype (TIP). Genes potentially affected by the overall activity score were screened using weighted gene co-expression network analysis (WGCNA). Based on the expression profile data of GC in The Cancer Genome Atlas (TCGA) database, COX analysis was applied to create an immune activity score (IAS). Differences in TME activity in the IAS groups were analyzed. We also evaluated the value of IAS in estimating immunotherapy and chemotherapy response based on immunotherapy cohort. Gene expression in IAS model and cell viability were determined by real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) and Cell Counting Kit-8 (CCK-8) assay, respectively.

Results

WGCAN analysis screened 629 overall activity score-related genes, which were mainly associated with T cell response and B cell response. COX analysis identified AKAP5, CTLA4, LRRC8C, AOAH-IT1, NPC2, RGS1 and SLC2A3 as critical genes affecting the prognosis of GC, based on which the IAS was developed. Further RT-qPCR analysis data showed that the expression of AKAP5 and CTLA4 was downregulated, while that of LRRC8C, AOAH-IT1, NPC2, RGS1 and SLC2A3 was significantly elevated in GC cell lines. Inhibition of AKAP5 increased cell viability but siAOAH-IT1 promoted viability of GC cells. IAS demonstrated excellent robustness in predicting immunotherapy outcome and GC prognosis, with low-IAS patients having better prognosis and immunotherapy. In addition, resistance to Erlotinib, Rapamycin, MG-132, Cyclopamine, AZ628, and Sorafenib was reduced in patients with low IAS.

Conclusion

IAS was a reliable prognostic indicator. For GC patients, IAS showed excellent robustness in predicting GC prognosis, immune activity status, immunotherapy response, and chemotherapeutic drug resistance. Our study provided novel insights into the prognostic assessment in GC.
Endoplasmic reticulum stress in the pathogenesis of alcoholic liver disease
Authors: Na Man , Yang Xingbiao , Deng Yongkun , Yin Zhaoheng , Li Mingwei
Published: November 2023

The endoplasmic reticulum (ER) plays a pivotal role in protein synthesis, folding, and modification. Under stress conditions such as oxidative stress and inflammation, the ER can become overwhelmed, leading to an accumulation of misfolded proteins and ensuing ER stress. This triggers the unfolded protein response (UPR) designed to restore ER homeostasis. Alcoholic liver disease (ALD), a spectrum disorder resulting from chronic alcohol consumption, encompasses conditions from fatty liver and alcoholic hepatitis to cirrhosis. Metabolites of alcohol can incite oxidative stress and inflammation in hepatic cells, instigating ER stress. Prolonged alcohol exposure further disrupts protein homeostasis, exacerbating ER stress which can lead to irreversible hepatocellular damage and ALD progression. Elucidating the contribution of ER stress to ALD pathogenesis may pave the way for innovative therapeutic interventions. This review delves into ER stress, its basic signaling pathways, and its role in the alcoholic liver injury.
Percepções dos profissionais de secretariado executivo sobre o trabalho remoto
Authors: De Freitas Marina Lima Cunha , De Souza Rosália Beber
Published: November 2023

Este estudo tem como principal objetivo entender e analisar criticamente as percepções dos profissionais de Secretariado Executivo em relação ao trabalho remoto. A crescente adesão a essa modalidade, influenciada pela crise do Covid-19, e as mudanças trazidas pelas novas tecnologias de comunicação são pautas importantes para a pesquisa no campo Organizacional.
Nesse sentido, surgiu a necessidade de entender como os secretários executivos percebem e se adaptam a essa nova forma de trabalho, haja vista o aumento significativo dos trabalhos secretariais pelos meios digitais. A metodologia empregada envolveu entrevistas semiestruturadas junto a estudantes e profissionais de Secretariado Executivo, os quais possuem experiências em relação ao trabalho remoto, focadas em coletar suas percepções para que fosse possível utilizar a Análise do Discurso Crítica sobre os discursos produzidos. Os resultados preliminares permitiram entender mudanças e semelhanças nas percepções dos profissionais de secretariado sobre o trabalho remoto, bem como analisar suas complexidades.
Essential Amino Acid Composition of Noodles Analogue from Aerial Yam, Rice and African Yam Bean Flour Blend Using Response Surface Methodology
Authors: Egbuta Kalu Chibuike
Published: November 2023

Response surface technology was used to evaluate the essential amino acid of noodles analogue from Aerial yam (Dioscorea bulbifera), Rice (Oryza sativa), and African yam bean (Sphenostylissternocarpa) flour mixture. Flours from Aerial yam, rice, and African yam bean were individually produced blended in the ratio of 50%: 25%: 25%, respectively and extruded using Brabender single screw laboratory extruder (Duisburg DCE 330 Model) filled with 3.0mm die nozzle diameter. A central composite rotatable design ( CCRD) with three variables, namely barrel temperature, feed moisture content and screw speed and fire level coded -a, -1, 0, +1, +a, was used in the experimental design to obtain 20 samples of noodles analogue. Essential Amino Acid profiling was done on the noodles analogue and data was analyzed by regression analysis. Results showed that lysine content ranged from 4.55 to 7.55mg/100g, valine content ranged from 3.81 to 5.06mg/100g, methionine content ranged from 0.86 to 2. 24mg/100g, phenylalanine content ranged from 5.06 to 5.45mg/100g, histidine content ranged from 3.09 to 4.20mg/100g, tryptophan content ranged from 0.83 to 1.96mg/100g, leucine content ranged from 6.87 to 7.90mg/100g, isoleucine content ranged from 2.91 to 4.91mg/100g, threonine content ranged from 3.55 to 4.44mg/100g. The coefficients of determinations (R2) were high and ranged from 0.8987 to 0.9916 at 5% level. The response surface plots suggest that the models developed had a good fit and the CCRD was effective in explaining the effect of the process condition on noodles analogue as influenced by barred temperature, feed moisture content and screw speed of the extruder. The data obtained from the study could be used for the control of product characteristics. The study indicated improved noodles analogues from Rice, Aerial yam, and African Yam Bean can be produced as noodles analogues.