bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamism and Cooperativity Essential for Efficient Catalysis in Aspergillus Niger Monoamine Oxidase
Authors: Curado-Carballada Christian , Feixas Ferran , Osuna Sílvia
Published: February 2019

Aspergillus niger Monoamine Oxidase (MAO-N) is a homodimeric enzyme responsible for the oxidation of amines into the corresponding imine. Laboratory evolved variants of MAO-N in combination with a non-selective chemical reductant represents a powerful strategy for the deracemisation of chiral amine mixtures and, thus, is of interest for obtaining chiral amine building blocks. MAO-N presents a rich conformational dynamics with a flexible ß-hairpin region that can adopt closed, partially closed and open states. Despite the ß-hairpin conformational dynamics is altered along the laboratory evolutionary pathway of MAO-N, the connection between the ß-hairpin conformational dynamics and active site catalysis still remains unclear. In this work, we use accelerated molecular dynamics to elucidate the potential interplay between the ß-hairpin conformational dynamics and catalytic activity in MAO-N wild type and its evolved D5 variant. Our study reveals a delicate communication between both MAO-N subunits that impacts the active site architecture, and thus its catalytic efficiency. In both MAO-N WT and the laboratory evolved D5 variant, the ß-hairpin conformation in one of the monomers affects the productive binding of the substrate in the active site of the other subunit. However, both MAO-N WT and D5 variants show a quite different behaviour due to the distal mutations introduced experimentally with Directed Evolution.
Elgetako farmazian II motako Diabetes Mellitusa (DM2) pairatzeko arriskua izango duten herritarrak antzemateko programa pilotua
Authors: Azpiazu Ane , Oñatibia-Astibia Ainhoa , Garitano Amaia , Osinalde Nerea , Elkoro Elena
Published: February 2019

II motako Diabetes Mellitusa (DM2) Espainiako hirugarren gaixotasun kroniko nagusia da. Gaixotasunak duen prebalentziagatik eta horren prebentzioaren garrantziagatik, Gipuzkoako farmazietan “DM2a Pairatzeko Arriskua Antzemateko Programa” jarri da martxan 2017ko urtarrilean. Helburua, Elgetako botikan, programan parte hartzen duten gizabanakoek DM2a pairatzeko duten arriskua kalkulatzea eta Elgetako biztanleriaren osasun-egoera aztertzea da. Horrez gain, komunitateko farmaziak DM2a pairatzeko arriskuaren detekzioa komunitateko zerbitzu farmazeutiko bezala bultzatzea du helburu. Programak 6 hilabeteko iraupena izan du eta ikerketa prospektiboa izan da. Gaixotasuna pairatzeko arriskua kalkulatzeko Findrisk testa erabili da eta osasun-egoeraren ikuspegi orokorragoa lortzeko pazienteei presio arteriala neurtu zaie. Arestian aipatutako programan, Elgetako botikan, 58 pertsonak hartu dute parte. Horietatik, 10 urtetan DM2a pairatzeko arrisku baxukoak 7 pertsona (%12,1), ertainekoak 36 (%62,1) eta altukoak 15 izan dira (%25,8). Hipertentsioarentzako medikamentua hartzen ez zuten 37 pertsonetatik 15 (%40,5), pre-hipertentso edo hipertentso bezala sailkatu dira. Hipertentsioaren kontrako medikamentua hartzen zuten 21 pertsonetatik 12 (%57,1) ez daude kontrolpean. Lortutako emaitzek Elgetako biztanleriaren osasun-egoera oro har ona dela erakusten dute. Hala ere, hainbat neurketatan (gerriko perimetroa, eguneroko ariketa fisikoa eta hipertentsioa), ahuleziak antzeman dira. Hori dela-eta, Elgetako biztanleriaren osasun-heziketa indartu behar dela ondorioztatu da.
Emakumezkoaren gernu-inkontinentzia
Authors: Andrés Maider
Published: February 2019

Emakumezkoetan gernu-inkontinentzia (GI) sarritan agertzen den osasun-arazo bat da, haien bizikalitatea sendo asaldatzen duena; halere, lotsa edota informazio faltagatik ia erdiek ez dute kontsultatzen. Gernu-inkontinentzia mota ezberdinak daude eta horien artean bi dira nagusiak: premiazko gernu-inkontinentzia (PGI) eta estresagatiko gernu-inkontinentzia (EGI). Bai ginekologoak bai urologoak azter dezake arazo hau eta beharrezko ikerketa burutu ondoren tratamendu egokiena ezarri; hasteko teknika kontserbatzaileak erabiltzen dira, zeinak zoru pelbikoko muskuluen indartzean, gernu-maskuriaren heziketan edota eguneroko bizi-ohiturak aldatzean oinarritzen diren. Horiek porrot egiten badute, inkontinentzia motaren arabera tratamendu ezberdinak daude. PGIan tratamendu farmakologikoa erabil dezakegu, antimuskarinikoak edota beta 3 agonista adrenergikoak hain zuzen. EGIaren kasuan, ostera, kirurgiara joko dugu; badaude horretarako hainbat teknika, urteetan zehar hobetuz joan direnak, gaur egun erabiliena uretra azpiko xingolak direlarik, polipropilenozkoak. Xingolen eraginkortasun-tasa altua da, mota ezberdinak daude bakoitza bere berezitasunekin eta horiek ezagutzea ezinbestekoa da pazienteari aholku egokiena emateko. Beraz funtsezkoa da emakumeek jakin dezaten gernu-inkontinentzia ez dela zahartzearen ondorio normal bat eta badaudela horretarako konponbideak.
Multidisciplinary, evidence-based consensus guidelines for human papillomavirus (HPV) vaccination in high-risk populations, Spain, 2016
Authors: Martínez-Gómez Xavier , Curran Adrian , Campins Magda , Alemany Laia , Rodrigo-Pendás José Ángel , Borruel Natalia , Castellsagué Xavier , Díaz-de-Heredia Cristina , Moraga-Llop Fernando A , del Pino Marta , Torné Aureli
Published: February 2019

Introduction: Although human papillomavirus (HPV) routine vaccination programmes have been implemented around the world and recommendations have been expanded to include other high-risk individuals, current recommendations often differ between countries in Europe, as well as worldwide.

Aim: To find and summarise the best available evidence of HPV vaccination in high-risk patients aiding clinicians and public health workers in the day-to-day vaccine decisions relating to HPV in Spain.

Methods: We conducted a systematic review of the immunogenicity, safety and efficacy/effectiveness of HPV vaccination in high-risk populations between January 2006 and June 2016. HPV vaccination recommendations were established with levels of evidence according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system.

Results: A strong recommendation about HPV vaccination was made in the following groups: HIV infected patients aged 9–26 years; men who have sex with men aged 9–26 years; women with precancerous cervical lesions; patients with congenital bone marrow failure syndrome; women who have received a solid organ transplant or hematopoietic stem cell transplantation aged 9–26 years; and patients diagnosed with recurrent respiratory papillomatosis.

Conclusions: Data concerning non-routine HPV vaccination in populations with a high risk of HPV infection and associated lesions were scarce. We have developed a document to evaluate and establish evidence-based guidelines on HPV vaccination in high-risk populations in Spain, based on best available scientific evidence.
A Note on Disaster Recovery
Authors: Fan-Osuala Onochie
Published: February 2019

This note provides a summary of disaster recovery with emphasis on information technology disaster recovery.
IMPLEMENTING A CYBERSECURITY COMMUNITY OF TRUST: REPRIVATA SEEKS AN “EARLY ADOPTER”
Authors: E Fulford James
Published: February 2019

Reprivata has developed a cybersecurity solution, which can fundamentally change how companies can create private, trust-based interconnections with their third party business partners. Now, how do they attract the right “early adopter” to implement it?
MYOCARDIAL INFARCTION WITH NONOBSTRUCTIVE CORONARY ATHEROSCLEROSIS AS A CURRENT PROBLEM OF EMERGENCY CARDIOLOGY
Authors: Ryabov V. V. , Fedorova S. B. , Vyshlov E. V.
Published: February 2019

Myocardial infarction with nonobstructive coronary atherosclerosis is a term which emerged recently, but it is of great importance for current clinical practice. Under the mask of this diagnosis, not only ischemia-caused myocardial infarction is hiding, but also diseases with alternative mechanisms of myocardial injury. This review presents a definition of this term as well as differential diagnostic algorithm for diseases associated with increase in the myocardial injury markers. The role of magnetic resonance imaging is emphasized as it is the key method for diagnosis of cardiac diseases. Main principles of current recommendations in this regard are presented. Unsolved and undeveloped aspects of this problem are discussed. Directions for future research are outlined.
PILOT RESULTS OF STUDYING CARDIAC MICROPOTENTIALS IN PATIENTS WITH MYOCARDIAL INFARCTION AND CARDIOGENIC SHOCK
Authors: Maximov I. V. , Avdeeva D. K. , Ivanov M. L. , Zimin I. A. , Yuzhakov M. M. , Turushev N. V. , Kodermyatov R. E. , Balakhonova M. V. , Tsoy E. I.
Published: February 2019

Aim. To study cardiac micropotentials registered by the hardware and software complex with nanosensors in patients with myocardial infarction for the early detection of life-threatening conditions.Materials and Methods. The pilot study included 29 patients with acute myocardial infarction who had life-threatening complications such as heart rhythm disorders, the development of acute left ventricular failure, or clinical death prehospitally or at admission to the coronary care unit. The diagnosis of myocardial infarction was established and treatment was carried out according to the national guidelines for the management of patients with myocardial infarction, including the methods of myocardial revascularization.Results. During hospitalization, eight patients developed cardiogenic shock and died. 21 patients survived and were included in the comparison group. At admission, all patients underwent high-resolution electrocardiography using the originally developed hardware and software complex with nanosensors. The micropotentials on the ST segment of the electrocardiogram were recorded for 30 s in three leads on-line. The numbers of micropotentials in the studied groups were analyzed. The analysis of the number of micropotentials within certain ranges of amplitude and duration registered on high-resolution electrocardiogram showed a decrease of the micropotential number in group of patients who died from cardiogenic shock compared with the group of survived patients.Conclusions. The results of this pilot study of cardiac micropotentials are preliminary and require further accumulation of data as well as a search for new criteria for diagnostics, prognosis, and evaluation of the treatment efficacy in patients with myocardial infarction.
Mal de Debarquement syndrome: clinical cases and literature review
Authors: Paškonienė A. , Poškutė R. , Markevičiūtė V. , Ivaška J. , Lesinskas E.
Published: February 2019

Background. Mal de Debarquement syndrome (MdDS) is a rare neuro-otologic disorder that mainly appears for middle-aged women and occurs after long-term passive motion (flight by plane, cruise). The syndrome symptoms can be persistent dizziness, sensation of rocking, unsteadiness, and disequilibrium. The syndrome diagnostics is complicated because there is no instrumental examination that could help to diagnose disorder thus neuro-otological examination is non-informative. The diagnosis is based on anamnesis, therefore, MdDS is often undiagnosed or inappropriate diagnosis is determined. To the knowledge of the authors, there are no publications on this syndrome in the Lithuanian language. Therefore, the aim of this article is to introduce this syndrome to Lithuanian doctors by presenting cases diagnosed in Lithuania and diagnostic criteria as well as by reviewing information published in the literature.Methods. Two clinical cases are described. Mal de Debarquement syndrome was diagnosed for two middle-aged women after air travel. Both women complained of sudden dizziness after the trip, however, neuro-otological examination had not revealed any pathology. In the literature review, 21 articles are overviewed describing the Mal de Debarquement syndrome.Results. Diagnostic criteria that helped to diagnose the Mal de Debarquement syndrome in 2016 are presented. A diagnostically significant feature of MdDS is a reduction in symptoms after the patient returns to passive motion. MdDS is often accompanied by anxiety and depression. Research shows that stress-reducing therapy, medications for migraine prophylactic, and lifestyle changes are effective in reducing symptoms and improving the quality of life.Conclusions. MdDS is still a rarely diagnosed disorder in many countries. Clinical symptoms and history of long-term passive motion is especially important for the diagnosis. Neurootological examination is required for differential diagnosis from other clinically similar diseases.
COMPLIANCE AUDITING IN PUBLIC ADMINISTRATION: UKRAINIAN PERSPECTIVES
Authors: Slobodianyk Yuliia , Shymon Svitlana , Adam Volodymyr
Published: February 2019

Purpose. In December 2016, the updated INTOSAI standards for government auditing were enacted that provided a methodological basis for conducting various forms of public audit, in particular, public compliance auditing. The use of ISSAIs is aimed at maintaining high-quality control measures to ensure the public administration system accountability and transparency. The aim of the research is to consider the current state and prospects of introducing the public compliance auditing into the practice of the Supreme Audit Institution in Ukraine. Design/ methodology/approach. The methodological basis of the study was to conduct the best practices comparative analysis in public auditing and to implement the desktop study of theoretical scientific researches, open analytical data produced by governmental and non-governmental bodies. Findings. The analysis of the Accounting Chamber of Ukraine’s reports proved that the control activities contained the compliance auditing elements. In this context, a proper legal framework for carrying out compliance auditing is not yet established and the appropriate methodological developments are not available. The author believes that implementing the ISSAI standards for the public compliance auditing may be accelerated due to the step-by-step implementation of the activities proposed. Practical implications. The specific recommendations on implementing the compliance auditing in accordance with the ISSAI standards requirements are important to regulators. Originality/value. The study can be the basis for further research in the field of the public compliance auditing theory and methodology, and the results may be useful for practitioners.
Muodonmuutoksia ja näkymättömiä yhteyksiä
Authors: Opas Minna
Published: February 2019

This article discusses pre- and post-natal rituals and restrictions among the Yine of Peruvian Amazonia. The observations are based on my fieldwork in one Yine community in Eastern Peru in the years 2000 and 2003. The article illustrates how birth-related restrictions adhered to by Yine parents correspond to wider cosmological principles that are manifested in other spheres of their life as well. These cosmological principles are approached from the point of view of Amerindian perspectivism. The two main principles highlighted here are transformation and mutation and that of linkages between persons and different items or objects. Transformations may take place not only in the context of birth but also in the interaction with different spiritual or corporeal beings. In a similar manner, linkages through which different subjects or objects affect each other may form not only between parents and children but also e.g. between hunter and his equipment, or a person and his clothes or other belongings.
Sukupuolittunut ruumiillisuus, puhtaus ja saastaisuus Suomen Hare Krishna -liikkeessä
Authors: Ahonen Johanna
Published: February 2019

This article examines gender and the representations of women in the Hare Krishna movement. I concentrate on embodiment, sexuality and gendered themes of purity and impurity. The primary research material consists of interviews with five committed Finnish female members and a period of participant-observation in the Hare Krishna community. The article also includes analysis of the movement’s religious texts. Drawing from poststructuralists Michel Foucault and Judith Butler, my work approaches the body as discursively constructed and connected to power. From Butler’s viewpoint I examine gender as a performative and embodied style. Thus, in context of the Finnish Krishna movement I ask how gender differences and certain kinds of religious, gendered and sexualized subjects are produced and how the appropriate female body is constructed. An interesting problem for theorizing gender vis-à-vis the Hare Krishna movement is the intense yearning to transcend the body. The strong dualism (spiritual/physical) in the Krishna movement is also worthy of consideration, since the physical body is an inevitable instrument in all the activities of a Krishna worshipper’s spiritual life.
Piika, taivaallintu ja agitaattoriakka
Authors: Mahlamäki Tiina
Published: February 2019

In this article I describe how the relationships between women and religion are represented in a set of books by Eeva Joenpelto. The Lohja-series, whose name comes from the story’s milieu, is made up of four novels published in the 1970s. It describes a village in southern Finland during the 1920s and 1930s, i.e. the period between the two wars, the Civil War and the Winter War. From the novels, I take three female characters who represent different gendered presentations of religion. Mari, the faithful servant of God, derives her strength from Lutheranism, and thus endures the hard and endless daily grind in the kitchen. Sofi is a childlike bride of Christ who finds her place in the Pentacostal movement and expresses her religion in charismatic and passionate ways. Tilta is an agitator who has found her life’s meaning in the Communist Party. My questions are the following: What kinds of possibilities for religious expression and fulfillment are available to women in the Lutheran Church and the Pentacostal movement? What is the place of religion in women’s every-day life? How do women outline the categories of sacred and profane, of purity and impurity, or do they combine them? How does a commitment to political ideology offer a woman a meaning system analogical to religion?
Velisurmasta suvun muistoksi
Authors: Haanpää Riina
Published: February 2019

The oral tradition of my family has preserved plenty of stories about fights, knifings and other crimes. One prominent character of these stories is Veikko, my grandfather’s brother, who stabbed his own brother to death. In this article, I examine this incident as it is represented in the relatives’ stories. For this study I relied on interviews I conducted on Veikko in 2001. I concentrate on the question of how the image of this incident is presented in reminiscences: why and how are stories about it told according to different generations? What sorts of inter- pretations and community values – also family values – do the stories of Veikko convey? And how is this incident possible to be seen as a part of divergent deaths. This article also highlights some of the difficulties arising when the researcher studies her own family traditions.
Rituaali, identiteetti ja ylirajaisuus
Authors: Davydova Olga
Published: February 2019

In this article I ponder the relationship between rituals and identities in the context of the remigration of persons of Finnish origin from Russia to Finland. The traditional ethnological study of rituals of death presupposes that ritual has to do with the community’s system of values and answers the main questions of human existence concerning the possibility of eternal life. In this conception of ritual the person is seen as a member of collective and a carrier of its culture. On the contrary, the postmodern theory of subjectivity releases the subject from membership in the stable group, but argues that identification is a flexible strategic process, serving the individual’s and group’s future goals. Using examples of official Soviet-era funeral scenarios and unofficial Russian folk-religious funerals, I analyze those cultural models and ideologies. Through my own experiences of funerals in Petrozavodsk and Joensuu I introduce the multivoicedness of funeral practices. Remigration to Finland is a part of present-day Finnish nationalism on the one hand, and global transnational migration and diasporic space on the other. A return migrant’s ethnic, national, ideological and cultural identification tends to be multi- layered, inconsistent and hybrid. Conducting ritual according to a certain canon does not automatically express the “true identity” or moral values of the community, but rather perceived configurations of cultural power-relations of the society of residence.
Poissaolevan politiikkaa. Historia ja perinteinen kulttuuri nenetsien etnisyyden rakennusaineina
Authors: Lukin Karina
Published: February 2019

The article deals with Nenets ethnicity and its connections with history and tradition, and it is based on the ethnographic fieldwork made in Nenets autonomous okrug in periods of varying length in 2000, 2003, 2004 and 2005. Besides participant observation and interviews, the material consists of archive and news paper material and literature describing Nenets history. I use the terms ethnicity, heritage, and politics of history as key concepts with which I define how Nenets ethnicity is constructed and articulated around the discussion about the fortification of Pustozersk and its 500th anniversary in 1999. The Nenets opened their own monument, Hèbidja Ten, during the anniversary celebrations and thus brought out a differing memory of the past. This evoked many debates over the right way of telling the history. Describing discussions about history, the opening ceremony, and also other activities of Nenets intelligentsia, this article argues that Nenets ethnicity is constructed on two absents, namely the traditional way of life and the glorious history. Still, in the current post-Soviet context, these two are made meaningful parts of Nenets ethnicity.
Huumori tekstin ja kokemuksen risteyksessä – Huvittavuuden prosessin systeemiteoreettisia suuntaviivoja
Authors: Talve Jukka
Published: February 2019

Humour, as a concept, comprises a broad range of human everyday experience. Barely a day passes without a humorous situation. Still, it has been amazingly hard to pinpoint the identity of the phenomenon in question. Humour seems to escape any attempts of scientific definition. In this article, humour is approached from the second order cybernetic viewpoint, which has not been widely known in the contemporary cultural sciences. The objective of the article is not to define humour, but to consider how humour relates to general concepts of text and experience on the one hand, and to the process of amusement on the other. It is argued that humour cannot be understood only in terms of text. Humour is seen as an emergent property of cultural experience that cannot be reduced to the sum of its parts. Second order cybernetics is treated as a vehicle for understanding humour and amusement as immanent processes that are brought forth by the cultural subject himself.
Spektaklet Susan Boyle på YouTube
Authors: Kumlin Annika
Published: February 2019

In her article, Annika Kumlin analyzes a YouTube video clip introducing Susan Boyle, the middle aged woman who took Britain by a storm in the Britain’s Got Talent reality show in 2009. The focal point in the article is the judges’ and audience’s surprised, even appalled reaction to her, as she appears on the stage for the very first time at the show. The video clip is only one minute and 17 seconds in lenght, but very rich in meaning, when it comes to the presentation and normative evaluation of a middle aged female body in a tv show. Based on her analysis of the clip, and taking the position of an participating observer, Kumlin seeks to understand the quality and amount of attention Susan Boyle’s appearance received at the time. Kumlin uses critical discourse analysis in combining physicality, gender, and age into a discursive construction about femininity and the grotesque.
Pinomäen ajat
Authors: Niukko Kirsi
Published: February 2019

This article examines a group of Swedish houses in Pinomäki district in Pori built during the reconstruction period which followed the Winter War (1939 – 1940) and the Continuation War (1941 – 1944; Second World War). The purpose of the article is to explore the research work on built cultural environment from the point of view of resident interviews, and it is aimed at discussing the importance of folkloristics and intangible cultural heritage in the fieldwork concerned with built environment. The folkloristic approach has not traditionally been combined with cultural heritage research. However, in this article the starting point is that especially in building inventories, which are compiled for the purpose of acting as background reports for zoning, the folkloristic perspectives are related to space through the narrative elements therein. As part of the building inventories, resident interviews are conducted, in which the residents inform the researcher about modifications and repairs made in the building. When buildings are described, they do not appear as a separate physical phenomenon, but various life events are integrated into the stories. Based on these stories, the researchers focus on picking out information that is related to living and building use. Through this information, concrete connections can be found to the area and to the historical events which have shaped it. The stories told by residents are especially essential in cases where no other information is available on the area. When it comes to the reconstruction period, the importance of intangible cultural heritage as well as the stories told by the residents are significant, because the residential areas are rather similar to each other in appearance and their interpretation methods have become stereotypical. The present and former residents of Pinomäki district in Pori provided a significant amount of new information about the construction and the occupation of the area, which has not been written down before. Thus it is important to increasingly evaluate the significance of building inventories and to aim at developing a method to comprehend more widely the crucial role that the intangible cultural heritage has in cultural environmental processes.
Kokemuksia Kolin kansallispuistosta ja -maisemista
Authors: Laurén Kirsi
Published: February 2019

Artikkelissa tutkitaan Itä-Suomen kansallispuistoihin liittyvän kirjoituskilpailun (2013) tuloksena saatuja Kolin kokemuskertomuksia. Kansallisromantiikan ajan taiteilijat esittivät Kolin erämaisen ja kalevalaisen maiseman symbolina, joka punoutui osaksi suomalaisuudesta rakennettua kertomusta. Artikkelin lähtökohtana on tarkastella Kolin menneisyyteen liittyvien hallitsevien kertomusten suhdetta nykypäivän luontokokemuksiin. Tutkimus osoittaa kirjoittajien ottavan voimakkaasti vaikutteita kansallisten maisemakuvastojen ja matkailumainonnan ylläpitämistä Koli-kuvastoista, joissa Koli esitetään suomalaisen taiteen kultakaudella luodulla tavalla. Nykypäivän Koli-kertomuksissa kirjoittajat rakentavat luontosuhdettaan ilmentävää identiteettiään tavalla, jossa kansallismaiseman symboliset merkitykset kietoutuvat osaksi luonnon ja maiseman henkilökohtaista kokemista. Kolin vaarojen päällä maisemakokemukset sävyttyvät alueen kulttuurisesta menneisyydestä kumpuavilla romanttisilla mielikuvilla. Vaarojen alapuolella taas luontokokemukset ovat arkisempia, joskin myös elämyksellisiä ja mieleenpainuvia, mutta ne eivät ole kansallisten konnotaatioiden värittämiä samalla tavoin kuin vaarojen yläpuolella.
Pelatihan Pembuatan Artikel Ilmiah bagi Mahasiswa Prodi PPKn Universitas Muhammadiyah Ponorogo
Authors: Asmaroini Ambiro Puji , Cahyono Hadi
Published: February 2019

Academic articles means as the development of student knowledge. Some benefits can be obtained from writing the academic articles. The benefits of writing the academic articles are: 1) delivering and developing ideas from students, 2) giving the academic impact for the students, 3) having a scientific work in the form of academic articles that can be published at local, national, and international journals. Training for writing the academic articles for the civic education students, Muhammadiyah University of Ponorogo aimed to make students understand how to create academic articles and able to determine the ideas tha have to be written in making academic articles. The methods used in this activity include training and practice, interviews / interviews, and lectures. There were 32 students of Civic education students who attend the training and they produced 15 titles of academic articles. The title was developed into an academic article framework. In the last stage, one of the selected student articles was published in the journal of Education and Citizenship Program of Civic Education Department, Muhammadiyah University of Ponorogo, January 2018 edition.Keywords: academic articles, students of Civic Education, Journal articleABSTRAKArtikel ilmiah merupakan sarana mengembangkan pengetahuan mahasiswa. Banyak manfaat yang bisa diperoleh dari penulisan artikel ilmiah. Adapun manfaat yang diperoleh menulis artikel ilmiah antara lain: 1) Menyampaikan dan mengembangkan ide dari mahasiswa, 2) memberikan dampak yang akademis bagi mahasiswa, 3) Memiliki karya berupa artikel ilmiah yang bisa dipublikasikan melalui jurnal lokal, nasional, maupun internasional. Pelatihan pembuatan artikel ilmiah bagi mahasiswa prodi PPKn Universitas Muhammadiyah Ponorogo bertujuan agar mahasiswa memahami cara dalam membuat artikel ilmiah dan mampu menemukan ide yang akan dituliskan dalam membuat artikel ilmiah. Adapun metode yang digunakan dalam kegiatan ini adalah meliputi pelatihan dan praktik, tanya jawab / interview, dan ceramah. Dari sekian mahasiswa prodi PPKn Universitas Muhammdiyah Ponorogo, terdapat 32 Mahasiswa yang mengikuti pelatihan, menghasilkan 15 judul artikel ilmiah. Judul tersebut dikembangkan menjadi artikel ilmiah. Pada akhirnya, salah satu artikel karya mahasiswa terpilih, berhasil diterbitkan di jurnal Pendidikan dan Kewarganegaraan Prodi PPKn Universitas Muhammadiyah Ponorogo edisi Januari 2018.
Influence of Rater Training on Inter- and Intrarater Reliability When Using the Rat Grimace Scale
Authors: Zhang Emily Q , Leung Vivian SY , Pang Daniel SJ
Published: February 2019

Rodent grimace scales facilitate assessment of ongoing pain. Reported rater training using these scales varies considerably and may contribute to the observed variability in interrater reliability. This study evaluated the effect of training on interrater reliability with the Rat Grimace
Scale (RGS). Two training sets (42 and 150 images) were prepared from acute pain models. Four trainee raters progressed through 2 rounds of training, scoring 42 images (set 1) followed by 150 images (set 2a). After each round, trainees reviewed the RGS and any problematic images with an experienced
rater. The 150 images were then rescored (set 2b). Four years later, trainees rescored the 150 images (set 2c). A second group of raters (no-training group) scored the same image sets without review with the experienced rater. Inter- and intrarater reliability were evaluated by using the intraclass
correlation coefficient (ICC), and ICC values were compared by using the Feldt test. In the trainee group, interrater reliability increased from moderate to very good between sets 1 and 2b and increased between sets 2a and 2b. Action units with the highest and lowest ICC at set 2b were orbital
tightening and whiskers, respectively. In comparison to an experienced rater, the ICC for all trainees improved, ranging from 0.88 to 0.91 at set 2b. Four years later, very good interrater reliability was retained, and intrarater reliability was good or very good). The interrater reliability
of the no-training group was moderate and did not improve from set 1 to set 2b. Training improved interrater reliability, with an associated reduction in 95%CI. In addition, training improved interrater reliability with an experienced rater, and performance was retained.
Creencias sobre el uso del condón en una población universitaria
Authors: Abril Valdez Elba , Román Pérez Rosario , Cubillas Rodríguez María José , Domínguez Ibáñez Sandra Elvia
Published: February 2019

Se describe y analizan creencias acerca del uso del condón en jóvenes universitarios con o sin antecedentes de relaciones sexuales. Se aplicó una encuesta a 1,514 estudiantes, hombres y mujeres seleccionados al azar mediante muestreo probabilístico. Del total, 62% reportó haber tenido relaciones sexuales y 38% dijo que no. Las creencias sobre el uso del condón fueron asociadas con la pérdida del placer, las dificultades de uso y los estereotipos de género, más por los varones que por las mujeres. Se concluye que en estudiantes universitarios persisten creencias poco favorecedoras acerca del uso del condón aun cuando no hayan iniciado relaciones coitales. De no promover cambios la tendencia se mantendrá con sus consecuentes riesgos.
El suelo y su multifuncionalidad: ¿qué ocurre ahí abajo?
Authors: Montaño Arias Noé Manuel , Navarro Rangel María del Carmen , Patricio López Itzel Carolina , Chimal Sánchez Eduardo , Miguel de la Cruz Jessica
Published: February 2019

Se expone la definición del suelo y su relación con sus procesos de formación. Asimismo, se destaca y ejemplifica la importancia ambiental y agrícola del suelo como un sistema multifuncional esencial para la recirculación de los nutrimentos, hábitat de microbiodiversidad, almacén de carbono y como proveedor de alimentos y otros servicios ambientales cruciales para el mantenimiento de la biodiversidad del planeta. Finalmente, se discute sobre las actuales estrategias y perspectivas para su estudio en México, dado que se trata de un recurso natural no renovable y clave para nuestra seguridad ambiental y alimentaria.
Borg’s category ratio-scale (CR-10) is useful to predict the onset of blood lactate accumulation (OBLA) in young Mexicans adults, regardless their body mass
Authors: Ramos Jiménez Arnulfo , Wall Medrano Abraham , Hernández Lepe Marco Antonio , Chávez Treviño Gregorio , Guereca Arvizuo Jaime , Hernández Torres Rosa Patricia
Published: February 2019

Aim: To evaluate the predictive value of Borg’s category ratio-scale (CR-10; 1-10) toward the onset of blood lactate accumulation (OBLA). Methods: 91 young Mexicans performed three non-consecutive sub-maximal exercise tests. Heart rate (HR), blood lactate and oxygen uptake were recorded at each CR-10 rating. Regression equations, reliable HR and CR-10 cut-off points of OBLA were then calculated. Results: HR (86 beats/min) and CR-10 (4.5) predicted OBLA with the same certainty, regardless the subject’s body mass. CR-10, HR and oxygen uptake, independently explained more than 60% of the associated variance to OBLA. Conclusions: CR-10 is useful to predict OBLA with almost the same certainty that HR, regardless the subject’s body mass.
KEDUDUKAN DAERAH K¬HUSUS PROVINSI PAPUA DAN PAPUA BARAT DALAM NEGARA KESATUAN REPUBLIK INDONESIA
Authors: Hadi Syofyan , Bernada Yaffed Septian Bernada
Published: February 2019

Indonesia adalah negara kesatuan yang menggunakan konsep desentralisasi. Desentralisasi diwujudkan dalam bentuk otonom daerah. Otonomi daerah memberikan kewenangan kepada daerah otonom untuk mengatur dan mengurus urusan pemerintahan. Praktek otonomi daerah dalam negara kesatuan tidak selalu sama, karena dipraktekkan juga otonomi daerah yang asymmetric. Salah satu bentuk otonomi daerah yang  asymmetric adalah otonomi khusus. Salah satu daerah yang berstatus otonomi khusus adalah Provinsi Papua dan Papua Barat. Karenanya dalam melaksanakan otonomi daerah, Provinsi Papua dan Papua Barat mempunyai kekhususan dalam melaksanakan kewenangan yang dimiliki. Namun demikian, pelaksanaan kekhususan yang dimiliki oleh Provinsi Papua dan Papua Barat tetap dalam kerangka Negara Kesatuan Republik Indonesia.
PERTANGGUNGJAWABAN PIDANA DALAM TINDAK PIDANA PEMILU (Studi Terhadap Pelanggaran Pemilu Di Indonesia)
Authors: Sulistyoningsih Dewi Permatasari
Published: February 2019

Tindak pidana pemilu merupakan tindak pidana khusus. Hal ini dapat dilihat dari jenis perbuatan, orangnya, dan peradilan yang mengadili. Tindak Pidana pemilu, merupakan kejahatan dengan dimensi baru. Oleh karena itu perlu penanganan khusus dari penegak hukum, terutama dalam menentukan subjek hukum, unsur, perbuatan. Fungsi dari Undang-undang Pemilu adalah merupakan sarana untuk mencegah tindakan-tindakan yang tidak demokratis terhadap pelaksanaan pemilu yang dalam ketentuannya banyak mengatur hal-hal yang pokok saja, maka sebelum ada peraturan pelaksananya sudah tentu dalam penerapannya akan menghadapi hambatan. Dalam kasus tindak pidana pemilu terdapat kesulitan bagi aparat penegak hukum, seperti untuk menentukan siapa yang menjadi subjek tindak pidana pemilu.
Education as a Complex System: Conceptual and Methodological Implications
Authors: Jacobson Michael J. , Levin James A. , Kapur Manu
Published: February 2019

Education is a complex system, which has conceptual and methodological implications for education research and policy. In this article, an overview is first provided of the Complex Systems Conceptual Framework for Learning (CSCFL), which consists of a set of conceptual perspectives that are generally shared by educational complex systems, organized into two focus areas: collective behaviors of a system, and behaviors of individual agents in a system. Complexity and research methodologies for education are then considered, and it is observed that commonly used quantitative and qualitative techniques are generally appropriate for studying linear dynamics of educational systems. However, it is proposed that computational modeling approaches, being extensively used for studying nonlinear characteristics of complex systems in other fields, can provide a methodological complement to quantitative and qualitative education research approaches. Two research case studies of this approach are discussed. We conclude with a consideration of how viewing education as a complex system using complex systems’ conceptual and methodological tools can help advance education research and also inform policy.
"If you’re not a liberal when you’re young": to the political biography of Đorđe Stratimirović
Authors: Novoseltseva Lyudmila
Published: February 2019

Đorđe Stratimirović (1822-1908) is a romantic fgure in the history of the Serbian national movement in the second half of the nineteenth century. A born leader and inspirer, he played an important role in the Revolution of 1848-1849 and remained in the memory of generations as People’s General. However, his further activities were thrown out of the history of political thought of the Serbs of the Austrian monarchy as altering from his earlier views. As a mature man, he - under the infuence of political circumstances - turned from a young active liberal into a leader of the conservative direction. In 1872, he developed a program of the future moderate party, which included cooperation with the government of the Kingdom of Hungary. Given the Serbs were rather rallying around the liberals, uncompromising fghters for national rights, Stratimirović’s choice was a wrong move.
Slovak-Hungarian border area as a multicultural community and an object of artistic reflection (novels by L. Ballek and L. Grendel)
Authors: Shirokova Lyudmila
Published: February 2019

In the literature of Slovakia there is a traditional theme of coexistence and interaction of cultures of Slovak and Hungarian ethnic groups, first of all in the historically established border area.The article deals with the novels devoted to this topic, offering a view of
the Slovak-Hungarian community from two different sides.
A fragment of diplomatic mail (stateyny spisok) of A. S. Matveev embassy to Bohdan Khmelnytsky and other documents on Russian-Ukrainian relations in the 17th century in Book 120 of the archive of the Little Russia Office
Authors: Kochegarov Kirill
Published: February 2019

This is a publication of a diplomatic letter (stateyny spisok) of Artamon Matveev and dyak Ivan Fomin to Bohdan Khmelnytsky in June 1657. Until lately this only sourse on the last Russian mission to the hetman of Zaporizhia before his death did not draw much attention
of the historians. In the foreword to the publication the author dwells upon other documents unknown to previous researchers that are dedicated to Russian-Ukrainian relations in the 17th century.
COGNITIVE DISTORTIONS OF PATIENTS IN THE GAMBLING ADDICTS' CLUB - DIFFERENCES WITH REGARD TO AGE AND LENGTH OF TREATMENT
Authors: Petra  , Stojnic Donald , Ricijaš Neven , Zoričić Zoran
Published: February 2019

Background: Cognitive processes are important factors in the aetiology of pathological gambling and they are always important aspect of all gambling interventions. Among other things, the gamblers’ decision-making process and persistence in gambling is under the influence of their perception of the importance of knowledge/skills versus luck in different gambling activities. In this study, we examine cognitive distortions of pathological gamblers and their perceptions on the significance of luck versus knowledge/skills in different games of chance. Effects of age and length of treatment are also examined.Subjects and methods: A total of 65 pathological gamblers at the gambling addicts’ club in Zagreb were included in the study. Cognitive distortions were measured using a modified version of the Gambling related cognitive distortions scale (Ricijaš et al. 2011). Participant thoughts on the role of luck versus knowledge/skills in games of chance were measured with a questionnaire especially designed for this study. All instruments were self-assessment questionnaires and anonymously filled out during a group sessions.Results: In general, results showed moderate cognitive distortions in terms of gambling beliefs, but significant perception of the importance of knowledge/skills for some games, especially sports betting and card games. Younger patients and patients in treatment for longer period have lower illusion of control. Length of treatment also seem to effect gambling-related superstition beliefs and incorrect understanding of probability, as well as importance of knowledge/skills for success in sports betting and card games.Conclusions: The results of this study lead to the indirect conclusion that length of treatment is a positive factor, which likely influences gamblers’ cognitive distortions. This conclusion certainly requires additional examination using longitudinal studies, which would provide a better overview of whether these differences are in fact due to the length of treatment and also to confirm its value for future abstinence from gambling activities.
The #nofilter Self: The Contest for Authenticity among Social Networking Sites, 2002–2016
Authors: Salisbury Meredith , Pooley Jefferson
Published: February 2019

This study traces appeals to authenticity, over time, in the promotional material of leading social-networking sites (SNSs). Using the Internet Archive’s Wayback Machine, the public-facing websites of major SNS platforms—beginning with Friendster in 2002—were sampled at six-month intervals, with promotional language and visuals examined for authenticity claims. The authors tracked these appeals, with attention to changes in promotional copy, through to July 2016, among the most popular social media services (as determined by English-language web presence and active monthly user figures or, when unavailable, reported network size). The study found that nearly all SNSs invoked authenticity—directly or through language like “real life” and “genuine”—in their promotional materials. What stood out was the profoundly reactive nature of these claims, with new services often defining themselves, openly or implicitly, against legacy services’ inauthenticity. A recurring marketing strategy, in other words, has been to call out competitors’ phoniness by substituting (and touting) some other, differently grounded mode of authenticity. Since the affordances of social sites, even those touting evanescence or anonymity, make them vulnerable to similar charges, the cycle gets replayed with numbing regularity.
Hierarchy without Hegemony: Locating Boys in an Inclusive Masculinity Setting
Authors: McCormack Mark
Published: February 2019

In this article, the author details how 16–18-year-old boys ascribe to the tenets of inclusive masculinity in a U.K. secondary school that the author calls “Standard High.” Drawing on five months of participant observation and twelve in-depth interviews, this article demonstrates that the boys' masculinities are predicated in opposition to the orthodox values of homophobia, misogyny, and aggressiveness. Accordingly, the practices of subordination and marginalization described in hegemonic masculinity theory are not used to regulate masculine behaviors or obtain dominance in this setting. At Standard High, boys ascribing to different masculine archetypes can each maintain high social status. Nonetheless, a social hierarchy still exists. Here, boys are stratified in accordance to a popularity ranking, which is determined by the possession of a matrix of variables: Namely, charisma, authenticity, emotional support, and social fluidity.
Self-efficacy among patients with chronic diseases and its associated factors
Authors: Shakya Dayana
Published: February 2019

Background: Chronic diseases are in an increasing trend worldwide. Although, this rise may be due to a number of factors, one reason for the worldwide increase is due to better treatment protocols and higher awareness among patients. The management of chronic disease depends on the patient’s ability to alter the modifi able risk factors. The burden of disease can be decreased with better self- efficacy.

Objectives: To assess the self-efficacy among patients with chronic diseases

Methodology: In this descriptive, cross sectional study, data was collected purposively from 329 patients with chronic diseases presenting in the Medical outpatient department of Kathmandu Medical College. Face to face interview method was used to collect data using Chronic Disease Self-efficacy Scale and Patient Assessment Chronic Illness Care Questionnaire. Association with selected socio demographic variables were computed with Mann Whitney U and Kruskal Wallis H tests.

Results: The mean age of the patients was 62±13 years. Males, those earning, those never admitted in the hospital for their disease and those who exercised were found to have better self-efficacy. There was significant difference in self-efficacy in terms of age, education, marital status, caregivers and body mass index. Self-efficacy showed significant positive correlation with monthly family income and health care provider score whereas significant negative correlation with age and monthly cost of treatment.

Conclusion: Self-efficacy of patients with chronic disease can be improved with certain modifiable factors like daily exercise and appropriate body mass index. Younger patients, males, educated, employed and married patients were found to have better self-efficacy. Proper counselling by health care providers also improves self-efficacy.
How Alzheimer’s took toll on my Ba’s life and the lives around him
Authors: Shakya Selika
Published: February 2019

Not available.