bluuebunny/crossref_metadata_2025 huggingface dataset:
Lessons learned from applying established cut-off values of questionnaires to detect somatic symptom disorders in primary care: a cross-sectional study
Authors: von Schrottenberg Victoria , Toussaint Anne , Hapfelmeier Alexander , Teusen Clara , Riedl Bernhard , Henningsen Peter , Gensichen Jochen , Schneider Antonius , Linde Klaus
Published: January 2024

Introduction

Based on two diagnostic accuracy studies in high-prevalence settings, two distinctly different combinations of cut-off values have been recommended to identify persons at risk for somatic symptom disorder (SSD) with the combination of the Patient-Health Questionnaire-15 (PHQ-15) and the Somatic Symptom Disorder—B Criteria Scale (SSD-12). We investigated whether the reported sensitivity and specificity of both recommended cut-off combinations are transferable to primary care.

Methods

In a cross-sectional study, 420 unselected adult primary care patients completed PHQ-15 and SSD-12. Patients scoring ≥9 and ≥ 23 (recommended cut-off combination #1) or ≥ 8 and ≥ 13 (recommended cut-off combination #2) were considered test-positive for SSD, respectively. To assess the validity of the reported sensitivity and specificity in different low- to high-prevalence settings, we compared correspondingly expected proportions of test positives to the proportion observed in our sample.

Results

Based on combination #1, 38 participants (9%) were found to be test positive, far fewer than expected, based on the reported values for sensitivity and specificity (expected minimum frequency 30% with a true prevalence ≥1%). This can only be explained by a lower sensitivity and higher specificity in primary care. For combination #2, 98 participants (23%) were test positive, a finding consistent with a true prevalence of SSD of 15% or lower.

Discussion

Our analyzes strongly suggest that the sensitivity and specificity estimates reported for combination #1 are not applicable to unselected primary care patients and that the cut-off for the SSD (≥23) is too strict. Cut-off combination #2 seems more applicable but still needs to be tested in studies that compare screening findings by questionnaires with validated diagnostic interviews as reference standards in primary care populations.
Associations of rumination, behavioral activation, and perceived reward with mothers’ postpartum depression during the COVID-19 pandemic: a cross-sectional study
Authors: Matsunaga Miki , Okajima Junko , Furutani Kaichiro , Kusakabe Noriko , Nakamura-Taira Nanako
Published: January 2024

Introduction

The COVID-19 pandemic has led to increased social isolation for mothers, and rumination exacerbates postpartum depression in mothers with poor social support. Although behavioral activation can help to decrease their depressive symptoms, the mechanism by which behavioral activation reduces postpartum depression remains unclear.

Methods

We examined the effects of rumination and behavioral activation on depression in postpartum women by examining a model mediated by subjective reward perception. A questionnaire was administered to 475 postpartum women (Age: Mean = 30.74 years, SD = 5.02) within 1 year of childbirth using an Internet survey. The measurements included perinatal depression, rumination, and behavioral activation, and we assessed environmental reward. To control for confounding variables, we assessed psychiatric history, social support, parenting perfectionism, and COVID-19 avoidance.

Results

Eighty-four (17.68%) mothers had possible postpartum depression. The covariance structure analysis showed that not only was there a direct positive path from rumination to postnatal depression but also a negative path via reward perception.

Discussion

This finding indicated that the COVID-19 pandemic could have increased depression in many of the mothers. Rumination not only directly relates to postpartum depression, but it could also indirectly relate to postpartum depression by decreasing exposure to positive reinforcers. In addition, having a history of psychiatric illness increases the effect of rumination on postpartum depression. These findings suggest that psychological interventions are needed to reduce rumination and increase contact with positive reinforcements to reduce postpartum depression, especially for high-risk groups.
Conventional weight loss therapy in morbid obesity during COVID-19 pandemic: degree of burdens at baseline and treatment efficacy
Authors: Schraml Jessica , Bauer Kerstin , Schild Sandra , Klos Bea , Erschens Rebecca , Stengel Andreas , Nieß Andreas , Zipfel Stephan , Mack Isabelle
Published: January 2024

Introduction

COVID-19 affected global physical and psychological health. The purpose of this study was to explore the pandemics impact on health-related quality of life (HRQoL), mental health (anxiety, depression, and perceived stress) and eating behavior in people with severe obesity participating in a multimodal conservative behavioral weight loss (BWL) program conducted via videoconferencing. Additionally, the efficacy of the six-month BWL program in a virtual video-based setting during the pandemic was examined.

Methods

297 participants of a face-to-face multimodal behavioral weight loss program prior to the pandemic (PrePAN, May 2014–September 2019) and 146 participants of the in terms of content same intervention in a videoconference-based setting during the pandemic (PAN, July 2020–April 2022) were questioned and compared using standardized questionnaires for HRQoL, symptoms of depressive and anxiety disorders, perceived stress, and eating behavior at baseline and at the end of treatment.

Results

Symptoms for anxiety, depression and perceived stress were similar between PrePAN and PAN at baseline. In addition, PAN tended to show lower disinhibition of eating behavior and feelings of hunger than PrePAN. During the pandemic, the BWL intervention resulted in body weight loss (67%) or stabilization (16%) in most of the participants. It also contributed by improving physical HRQoL, lower worries, and improved eating behaviors compared to baseline.

Conclusion

During the COVID-19 pandemic, baseline mental health of people with morbid obesity was not worse than before the pandemic. Additionally, the BWL intervention in the virtual video-based setting stabilized and improved physical and mental health during the COVID-19 pandemic.
How to address vaccine hesitancy? Lessons from National Hepatitis B Immunization Program in China
Authors: Jiang Haiting , Wei Chengyu
Published: January 2024

China, with the severe burden of hepatitis B, plays a significant role in the global efforts towards eliminating hepatitis B disease by 2030. Vaccination is recognized as the most effective measure to prevent infectious diseases. However, vaccine hesitancy remains a significant barrier to achieving herd immunity across diverse populations. To address this issue, the health ministries and public health authorities in China have implemented various measures to encourage hepatitis B vaccination. China’s National Hepatitis B Immunization Program, initiated in 1985, has been successful in controlling this vaccine-preventable disease. Given the challenges in eliminating hepatitis B, strengthening the National Hepatitis Immunization Program in China is of utmost importance. Through an analysis of policy documents, reports, and scientific papers, the history of the program was summarized, and effective approaches to address vaccine hesitancy were identified. This will help achieve universal health coverage of vaccines and effectively work towards meeting the goals set for 2030.
Mineralisation of CO2 in wood biomass ash for cement substitution in construction products
Authors: Tripathi Nimisha , Hills Colin D. , Singh Raj S. , Kyeremeh Stephen , Hurt Andrew
Published: January 2024

This study extends our exploration of the potential of biomass ashes for their CO2-reactivity and self-cementing properties. The ability of three hardwood-based biomass ashes to mineralise CO2 gas and partially replace CEM I in mortars was investigated. The three hardwoods were English oak (Quercus rober), English lime (Tilia x europaea), and beech (Fagus sylvatica). The woody biomass wastes were incinerated at 800°C to extract their key mineral phases, which are known to be reactive to CO2 gas to form carbonates. The selected biomass ashes were analysed for their CO2-reactivity, which was in the range of 32–43% (w/w). The ashes were used to replace CEM I at 7 and 15% w/w and this “binder” was mixed with sand and water to produce cylindrical monolithic samples. These monoliths were then carbonated and sealed cured over 28 days. The compressive strength, density and microstructure of the carbonate-hardened monoliths were examined. The ash-containing monoliths displayed mature strengths comparable to the cement-only reference samples. The CO2 uptake of oak containing monoliths was 7.37 and 8.29% w/w, for 7 and 15% ash substitutions, respectively. For beech and English lime they were 4.96 and 6.22% w/w and 6.43 and 7.15% w/w, respectively. The 28 day unconfined compressive strengths for the oak and beech ashes were within the range of ~80–94% of the control, whereas lime ash was 107% of the latter. A microstructural examination showed carbonate cemented sand grains together highlighting that biomass ash-derived minerals can be very CO2 reactive and have potential to be used as a binder to produce carbonated construction materials. The use of biomass to energy ash-derived minerals as a cement replacement may have significant potential benefits, including direct and indirect CO2 emission savings in addition to the avoidance of landfilling of these combustion residues.
Our Blue Planet: Connecting Humans and the Ocean
Authors: Kriegl Michael , Kochalski Sophia , Straka Tanja M. , Gorris Philipp , Schlüter Achim , Kluger Lotta C.
Published: January 2024

Dive into the incredible world of the ocean, a place full of wonder and beauty! The ocean is like a superhero, providing us with tasty seafood and other vital “services”. But trouble looms: climate change, plastic pollution, and intensive fishing endanger the ocean’s superpowers. Your help is needed to save the day! To keep the ocean healthy, we must understand how it works. Get ready to explore its mysteries through gigantic “webs” of interactions that reveal how we are connected to the ocean, how our actions impact the environment, and how the environment affects us. These webs are called social-ecological networks, and they are like maps that help us solve the ocean’s problems. Together, we can use social-ecological networks to secure a sustainable future for our blue planet. So, put on your diving mask, grab your snorkel, and let us make a splash for the ocean!
The effect of menthol rinsing before intermittent exercise on physiological, physical, and thermo-behavioral responses of male football referees in hot and humid environment
Authors: Roriz Maria , Brito João , Teixeira Filipe J. , Spyrou Konstantinos , Teixeira Vitor Hugo
Published: January 2024

Introduction

In the current experiment, we aimed to evaluate whether eliciting pre-exercise non-thermal cooling sensations would alter perceptual measures, and physical and physiological responses in football referees.

Methods

Nine highly trained male football referees undertook two 45-minute intermittent exercise protocols in hot and humid conditions (34.2 ± 0.6°C, 62.5 ± 1.0% relative humidity). In a randomized counterbalanced crossover design, 1 of 2 beverages were given before the warm-up: a 0.01% menthol solution or a placebo noncaloric solution. Physical performance was quantified as total distance covered in each of the three 15-minute exercise blocks. Core temperature, heart rate, thermal sensation and thermal comfort were measured at rest and after each exercise block.

Results

No changes were observed between trials and over time for distance covered. No main effect of mouth rinse was observed for core temperature and heart rate, but both increased over time in all conditions (P < 0.001). Thermal sensation and thermal comfort were significantly improved with menthol after mouth-rinsing (P < 0.05), but with no differences at any other time-point.

Discussion

These results indicate that non-thermal cooling oral stimuli provide immediate behavioral changes but may not influence physiological or physical responses in football referees, during intermittent exercise in hot and humid environments.

Clinical Trial Registration

www.clinicaltrials.gov, identifier NCT05632692.
Drivers of consumers’ intention to adopt sustainable healthy dietary patterns: evidence from China
Authors: Chen Xiujuan , Jiang Xue , Wu Linhai
Published: January 2024

Introduction

In line with the shift towards sustainable consumption, sustainable healthy dietary patterns (SHDP) have received considerable attention, but no study has examined Chinese consumers’ intention to adopt SHDP.

Methods

Based on the theory of planned behaviour (TPB), this study integrated health consciousness, environmental concerns, and past eating behaviour to construct an expanded TPB framework for analyzing the factors influencing Chinese consumers’ intention to adopt SHDP. The mediating role of attitude between perceived value and consumers’ intention to adopt SHDP was also analyzed. The study empirically tested the research model using structural equation modelling estimation, based on the data collected from 402 local consumers in Wuxi, China.

Results and discussion

The results showed that attitude, perceived behavioural control, health consciousness, and past eating behaviuor positively and significantly influenced consumers’ intention to adopt SHDP, whereas perceived value indirectly influenced adoption intention through attitude. Subjective norms and environmental concerns had no significant influence on adoption intention. Based on these findings, interventions through dietary education and information campaigns are recommended to enhance consumers’ value awareness and attitudes towards SHDP. Interventions, such as nudging, should be designed to enhance consumers’ perceived behavioural control and dietary practises. The findings of this study provide important insights for the development of dietary change intervention strategies.
Case Report: Successful R0 resection in locally advanced retroperitoneal sarcomas
Authors: Bael Peter , Alqtishat Bayan , Alshawwa Khaled
Published: January 2024

We present a case series of three successfully resected tumors in our center at Al-Makassed Hospital in Jerusalem, Palestine, all of which primarily involved or invaded adjacent structures and needed a multidisciplinary approach to achieve R0 resection. Our first patient is a 42-year-old previously healthy female with intermittent attacks of dull aching abdominal pain. Her tumor was a leiomyosarcoma that involved major vessels and other adjacent vital structures. Ultimately, she needed major highly advanced surgery necessitating the need for vascular reconstruction of the IVC, as well as R0 resection. The surgery was performed by a multidisciplinary team of highly specialized surgeons in related fields. Our second case is a 75-year-old female patient with a well-differentiated liposarcoma invading the upper pole of the right kidney, necessitating a nephrectomy. Consequently, this case demanded the interdisciplinary involvement of nephrology. Our third patient is a 59-year-old male with dedifferentiated liposarcoma that involved the spleen, pancreas, and splenic flexure while engulfing the left kidney and ureter. Beyond the removal of the tumor, multiorgan resection was imperative to achieve microscopic margin-free resection. This extensive local spread needed broad collaboration from the medical team and other surgical subspecialties. All surgeries went well, and their outcomes were promising. All patients had an uneventful follow-up and, to date, no recurrence. Invasive retroperitoneal sarcomas of different histological types and clinical stages represent a technical challenge. Careful preoperative investigation and an experienced, dedicated multidisciplinary team of surgeons and non-surgeons from related fields, including vascular, urologic, and hepatobiliary surgeons, are usually needed for a safe and successful R0 resection despite extensive tumor involvement in light of difficulty achieving early diagnosis.
Paneth cell ontogeny in term and preterm ovine models
Authors: Bautista Geoanna M. , Cera Anjali J. , Schoenauer Rebecca J. , Persiani Michele , Lakshminrusimha Satyan , Chandrasekharan Praveen , Gugino Sylvia F , Underwood Mark A. , McElroy Steven J.
Published: January 2024

Introduction

Paneth cells are critically important to intestinal health, including protecting intestinal stem cells, shaping the intestinal microbiome, and regulating host immunity. Understanding Paneth cell biology in the immature intestine is often modeled in rodents with little information in larger mammals such as sheep. Previous studies have only established the distribution pattern of Paneth cells in healthy adult sheep. Our study aimed to examine the ontogeny, quantification, and localization of Paneth cells in fetal and newborn lambs at different gestational ages and with perinatal transient asphyxia. We hypothesized that ovine Paneth cell distribution at birth resembles the pattern seen in humans (highest concentrations in the ileum) and that ovine Paneth cell density is gestation-dependent.

Methods

Intestinal samples were obtained from 126–127 (preterm, with and without perinatal transient asphyxia) and 140–141 (term) days gestation sheep. Samples were quantified per crypt in at least 100 crypts per animal and confirmed as Paneth cells through in immunohistochemistry.

Results

Paneth cells had significantly higher density in the ileum compared to the jejunum and were absent in the colon.

Discussion

Exposure to perinatal transient asphyxia acutely decreased Paneth cell numbers. These novel data support the possibility of utilizing ovine models for understanding Paneth cell biology in the fetus and neonate.
Genetic characterization of intramuscular myxomas
Authors: Hatchett William John , Brunetti Marta , Andersen Kristin , Tandsæther Maren Randi , Lobmaier Ingvild , Lund-Iversen Marius , Lien-Dahl Thomas , Micci Francesca , Panagopoulos Ioannis
Published: January 2024

Introduction: Intramuscular myxomas are benign tumors that are challenging to diagnose, especially on core needle biopsies. Acquired chromosomal aberrations and pathogenic variants in codon 201 or codon 227 in GNAS complex locus gene (GNAS) have been reported in these tumors. Here we present our genetic findings in a series of 22 intramuscular myxomas.

Materials and methods: The tumors were investigated for the presence of acquired chromosomal aberrations using G-banding and karyotyping. Pathogenic variants in codon 201 or codon 227 of GNAS were assessed using direct cycle Sanger sequencing and Ion AmpliSeq Cancer Hotspot Panel v2 methodologies.

Results: Eleven tumors carried chromosomal abnormalities. Six tumors had numerical, four had structural, and one had both numerical and structural chromosomal aberrations. Gains of chromosomes 7 and 8 were the most common abnormalities being found in five and four tumors respectively. Pathogenic variants in GNAS were detected in 19 myxomas (86%) with both methodologies. The detected pathogenic variants were p.R201H in nine cases (seven with abnormal and two with normal karyotypes), p.R201C in five cases, all with normal karyotypes, p.R201S in three cases (two with abnormal and one with normal karyotype), p.R201G in one case with a normal karyotype, and p.Q227E in one case with a normal karyotype.

Conclusion: Firstly, our data indicate a possible association between chromosomal abnormalities and GNAS pathogenic variants in intramuscular myxomas. Secondly, the presence of the rare pathogenic variants R201S, p.R201G and p.Q227E in 26% (5 out of 19) of myxomas with GNAS pathogenic variants shows that methodologies designed to detect only the common “hotspot” of p.R201C and p.R201H will give false negative results. Finally, a comparison between Ion AmpliSeq Cancer Hotspot Panel v2 and direct cycle Sanger sequencing showed that direct cycle Sanger sequencing provides a quick, reliable, and relatively cheap method to detect GNAS pathogenic variants, matching even the most cutting-edge sequencing methods.
Board Member Remuneration and Earnings Management: The Case of Portugal
Authors: Dias Catarina Gonçalves , Paiva Inna Choban de Sousa , Carvalho Luísa Cagica
Published: January 2024

This study draws on agency theory and evaluates the effect of the remuneration structures of board members on earnings management, proxied by discretionary accruals. To achieve the objective, this study uses a multiple regression model and a hand-collected dataset of Portuguese-listed firms from 2015 to 2019. This study suggests that fixed board remuneration is associated with lower levels of earnings management, as opposed to variable remuneration of board members, which is strongly associated with a higher level of earnings management. The findings based on this study provide useful information to investors and regulators in evaluating the effect of board compensation structure on earnings management. Additionally, this study expands the corporate governance literature by examining an under-researched mechanism to address the agency problem.
Comprehensive Economic Impacts of Wild Pigs on Producers of Six Crops in the South-Eastern US and California
Authors: McKee Sophie C. , Mayer John J. , Shwiff Stephanie A.
Published: January 2024

Wild pigs (Sus scrofa) cause damage to agricultural crops in their native range as well as in the portions of the globe where they have been introduced. In the US, states with the highest introduced wild pig populations are Alabama, Arkansas, California, Florida, Georgia, Louisiana, Mississippi, Missouri, North Carolina, South Carolina, and Texas. The present study summarizes the first survey-based effort to value the full extent of wild pig damage to producers of six crops in these eleven US states. The survey was distributed by the USDA National Agricultural Statistical Service in the summer of 2022 to a sample of 11,495 producers of corn (Zea mays), soybeans (Glycine max), wheat (Triticum spp.), rice (Oryza sativa), peanuts (Arachis hypogaea), and sorghum (Sorghum bicolor) in these 11 states. Our findings suggest that the economic burden of wild pigs on producers of these crops is substantial and not limited to the direct and most identifiable categories of crop damage (i.e., production value lost due to depredation, trampling and rooting). We estimate that the annual cost to producers of these six crops in the surveyed states in 2021 was almost USD 700 million.
Challenges to Food Security in the Middle East and North Africa in the Context of the Russia–Ukraine Conflict
Authors: Kozielec Anna , Piecuch Jakub , Daniek Kamila , Luty Lidia
Published: January 2024

In this article, the impact of the Russia–Ukraine conflict on food security in the Middle East and North Africa (MENA) region is analyzed. With Ukraine being recognized as one of the major global grain producers and exporters, the conflict is seen as posing a significant challenge to MENA countries, which are heavily dependent on grain imports from Ukraine. The importance of global linkages in food supply chains and their influence on regional food security is highlighted in this context. Utilizing secondary data from 2002 to 2021 obtained from the United Nations Food and Agriculture Organization (FAO), the study focuses on demography and food security, analyzing how these factors intertwine with grain export dynamics. The escalating hostilities have disrupted transportation routes, damaged infrastructure, and hindered logistics, resulting in substantial export volume reductions. Geopolitical tensions have exacerbated these effects, diminishing confidence among MENA grain importers. The study highlights how these disruptions have influenced global supply chains, prices, and agricultural product availability, with a specific focus on the MENA region’s challenges in food security, compounded by conflicts, climate change, and import dependence. A detailed demographic analysis reveals the impact of population changes on food demand and distribution, offering insights into how population growth and urbanization, alongside shifts in malnutrition and obesity rates, affect food security. The study concludes that the MENA region’s increasing reliance on food imports, coupled with climatic and political variabilities, underscores its growing vulnerability to global supply chain disruptions and the need for robust strategies to address these challenges.
Comprehensive Morphometric and Biochemical Characterization of Seven Basil (Ocimum basilicum L.) Genotypes: Focus on Light Use Efficiency
Authors: Branca Ferdinando , Treccarichi Simone , Ruberto Giuseppe , Renda Agatino , Argento Sergio
Published: January 2024

The choice of basil (Ocimum basilicum L.) genotypes determines key attributes such as yield, flavor, and adaptability, contributing significantly to the overall success and sustainability of basil cultivation practices. As the primary aim of this study, seven basil accessions were characterized for both their growth performance and biochemical profile of volatile compounds, enabling the differentiation among distinct chemotypes. As secondary objectives, growth performance and production were evaluated under natural solar radiation conditions (SR100) and with a 30% reduction in solar radiation using a net (SR70). Light use efficiency (LUE) determination revealed the plants’ biomass production capability under different solar radiation (SR) conditions. Genotypes A, B, C, and G were characterized by a high levels of linalool, which is typically associated with the “pesto” sauce smell. Lemon basil D exhibited a different chemotype due to the presence of neral and geranial. E and F displayed a different chemotype due to the higher concentration of α-bergamotene. The total fresh harvested biomass was significantly higher in SR70 than SR100 conditions. The second harvest in both SR conditions was the most productive one, while genotype E under SR70 displayed the highest yield. The landraces D and E showed the highest LUE values, indicating their capability in converting the solar radiation into fresh biomass. Plants grown in SR70 conditions registered significantly higher values of plant height, number of branches, and leaf weight. This work aimed to provide valuable insights into the selection of basil genotypes suitable for sustainable agriculture. Conversely, it lays the basis for cultivation aspects pertaining to the crop’s adaptability in peri-urban, marginal lands, which are characterized by limited solar radiation.
Impacts of Farrowing Pen Design, Season, and Sow Parity on Litter Performance and Piglet Mortality
Authors: Madeira Pacheco Verônica , Brown-Brandl Tami M. , Rohrer Gary A. , Vieira de Sousa Rafael , Silva Martello Luciane
Published: January 2024

Piglet mortality during lactation is a significant concern in swine production, influenced by complex interactions involving sow, piglet, environmental, and management factors. While crushing by the sow may be the ultimate cause of piglet mortality, there are many factors influencing the outcome, including parity, thermal stress, and animal housing systems. New farrowing systems are continuously being developed; however, it is difficult for producers to make decisions without any scientific basis. This study aimed to assess the impact of different farrowing pen layouts on piglet performance, considering parity and season. A total of 546 sows and 9123 piglets were monitored across 36 lactation cycles. Sows were randomly assigned to three farrowing pen layouts (standard, diagonal, and offset) in three rooms (20 sows by room). All farrowing pens had the same space allocations (2.7 m by 1.8 m and 2.1 m by 0.6 m for the sow area). The three types of farrowing pens were blocked by position within the room. Piglet performance traits (percent of stillborns, percent of mortality, percent of overlays, and average daily weight gain: ADG) and sows traits (health and parity) were monitored following US Meat Animal Research Center (USMARC) procedures. Results indicated that treatment, parity, and season influenced some piglet performance traits. The offset farrowing pen had a lower percent of stillborns compared to the standard. No significant differences were observed between the diagonal crate and the other treatments. When evaluating high mortality sow (>two piglets), the offset and standard treatments had a lower percent of overlays. Piglets from first-parity sows had lower ADG than those from higher-parity sows. A higher percent of overlays were observed in Autumn and Summer compared to Spring and Winter, and Summer had lower average daily weight gain than other seasons. The results suggest that modifying the layout (offset), with sows placed further away from the heating source, can reduce the percent of overlays in sows with high mortality (>2 piglets). In addition, the influence of season on the piglet production traits demonstrated the importance of proper management of the environment, even in systems with a certain level of climatic control.
Literature Review of the Principal Diagnostic Tests to Detect Bovine Respiratory Disease in Pre-Weaned Dairy and Veal Calves
Authors: Berman Julie
Published: January 2024

Bovine respiratory disease (BRD) is an infection of the upper and lower respiratory tract, characterized by an inflammation of the lung. Different diagnostic tests can be used to detect BRD, including clinical respiratory scoring systems, thoracic auscultation, and imaging tests like thoracic ultrasonography and thoracic radiography. Although commonly used, none of these diagnostic tests are perfect for detecting BRD. This article reviews the advantages and drawbacks of these techniques and their performance in detecting BRD in pre-weaned dairy and veal calves.
Evaluation of the Audicor Acoustic Cardiography Device as a Diagnostic Tool in Horses with Mitral or Aortic Valve Insufficiency
Authors: Piotrowski Isabelle L. , Junge Hannah K. , Schwarzwald Colin C.
Published: January 2024

Mitral and aortic valve insufficiencies have been commonly reported in horses. The objective of this study was to establish the use of acoustic cardiography (Audicor®) in horses with aortic (AI) or mitral valve insufficiency (MI). A total of 17 healthy horses, 18 horses with AI, and 28 horses with MI were prospectively included. None of the horses was in heart failure. Echocardiography and Audicor® analyses were conducted. Electromechanical activating time (EMAT), rate-corrected EMATc, left ventricular systolic time (LVST), rate-corrected LVSTc, and intensity and persistence of the third and fourth heart sound (S3, S4) were reported by Audicor®. Graphical analysis of the three-dimensional (3D) phonocardiogram served to visually detect murmurs. Audicor® snapshot variables were compared between groups using one-way ANOVA followed by Tukey’s multiple-comparisons test. The association between Audicor® snapshot variables and the corresponding echocardiographic variables was investigated by linear regression and Bland–Altman analyses. Heart murmurs were not displayed on Audicor® phonocardiograms. No significant differences were found between Audicor® variables obtained in clinically healthy horses and horses with valvular insufficiency. The Audicor® device is unable to detect heart murmurs in horses. Audicor® variables representing cardiac function are not markedly altered, and their association with corresponding echocardiographic variables is poor in horses with valvular insufficiency that are not in heart failure.
The Spatial Ecology of Nuisance Crocodiles: Movement Patterns of Relocated American Crocodiles (Crocodylus acutus) in Guanacaste, Costa Rica
Authors: Coleman Tyler Steven , Gabel Wray , Easter Michael , McGreal Maggie , Marin Mahmood Sasa , Garrigos Davinia Beneyto , Murray Christopher M.
Published: January 2024

Anthropogenic alterations of the environment have increased, highlighting the need for human–wildlife coexistence and conflict mitigation. Spatial ecology, and the use of passive satellite movement technology in particular, has been used to identify patterns in human–wildlife conflict as a function of shared resources that present potential for dangerous situations. Here, we aim to remotely identify patterns indicative of human–crocodile conflict in Guanacaste, Costa Rica by exploring site fidelity and diverse modes of movement (i.e., land and water) across space between nuisance (relocated) and non-nuisance (wild) crocodiles. Advanced satellite remote sensing technology provided near-constant movement data on individuals at the regional scale. Telonics Iridium SeaTrkr-4370-4 transmitters were used with modified crocodilian fitting. Results indicate that relocated crocodiles exhibited large-scale movements relative to wild crocodiles. Nuisance relocated crocodiles either returned to the area of nuisance or potentially attempted to in short time frames. The results presented here highlight the need for alternative management strategies that facilitate relocation efficacy.
Utero-Cutaneous Fistula in Ruminants: Characterization of the First Cases in Ewes and Cows
Authors: Câmara Antonio Carlos Lopes , Braga Gustavo Peixoto , Fidelis Andrei Antonioni Guedes , Dantas Fausto Romualdo de Faria , Borges José Renato Junqueira , Castro Márcio Botelho de
Published: January 2024

Reports on UCF in animals are still lacking in veterinary literature. Detailed clinical signs, laboratory findings, and follow-up information from the first cases of UCF in two ewes and two cows are provided. The cases occurred over a 12-year period. All ruminants presented a fistulous tract or perforated wound on the right ventral abdomen, emitting a foul-smelling secretion possibly associated with macerated fetal parts or placental remains. Laboratory findings included anemia, leukocytosis by neutrophilia, and hyperfibrinogenemia in one ewe, and hyperfibrinogenemia in one cow. Ovariohysterectomy and fistulectomy were performed in one ewe, while the other three ruminants were submitted for the removal of fetal parts and placental remains through the UCF. Two ewes died within 12–48 h, and the two Nelore cows had an uneventful recovery, achieving secondary intention healing within 30 to 35 days. As a never-reported or unnoticed disease of the reproductive tract, UCF is an unusual consequence of dead fetus retention in an end-stage pregnancy and a potentially life-threatening condition in ruminants, especially ewes. Further broad studies in large herds of cattle and small ruminant flocks must be conducted to estimate the incidence of UCF and ensure improvements in the diagnosis and knowledge of pathogenesis, aiming at prevention.
Correction: Pu et al. Exosome miRNA Expression in Umbilical Cord Blood of High-Parity Sows Regulates Their Reproductive Potential. Animals 2022, 12, 2456
Authors: Pu Qiang , Chai Jie , Chen Li , Liu Changbao , Yang Changfeng , Huang Yongfu , Luo Jia
Published: January 2024

In the original publication [...]
Connecting the Dots: Livestock Animals as Missing Links in the Chain of Microplastic Contamination and Human Health
Authors: Corte Pause Francesca , Urli Susy , Crociati Martina , Stradaioli Giuseppe , Baufeld Anja
Published: January 2024

Plastic pollution is a global diffuse threat, especially considering its fragmentation into microplastics (MPs) and nanoplastics (NPs). Since the contamination of the aquatic environment is already well studied, most studies have now focused on the soil. Moreover, the number of studies on the exposure routes and toxic effects of MNPs in humans is continuously increasing. Although MNPs can cause inflammation, cytotoxicity, genotoxicity and immune toxicity in livestock animals, which can accumulate ingested/inhaled plastic particles and transfer them to humans through the food chain, research on this topic is still lacking. In considering farm animals as the missing link between soil/plant contamination and human health effects, this paper aims to describe their importance as carriers and vectors of MNP contamination. As research on this topic is in its early stages, there is no standard method to quantify the amount and the characteristics of MNPs in different matrices. Therefore, the creation of a common database where researchers can report data on MNP characteristics and quantification methods could be helpful for both method standardization and the future training of an AI tool for predicting the most abundant/dangerous polymer(s), thus supporting policy decisions to reduce plastic pollution and perfectly fitting with One Health principles.
Streptococcus pneumoniae Infection in Patients with Asplenia: A Spanish Perspective over a 25-Year Period
Authors: Gea-Izquierdo Enrique , Rodríguez-Caravaca Gil , Gil-Prieto Ruth , Hernández-Barrera Valentín , Gil-de-Miguel Ángel
Published: January 2024

Anatomical or functional asplenia constitutes a risk factor for Streptococcus pneumoniae (SP) infection, being more frequent in children and the elderly and in people with multiple comorbidities. We aimed to describe the impact of invasive pneumococcal disease (IPD) on the clinical features and outcomes of patients hospitalized for asplenia in Spain. Discharge reports from the Spanish Minimum Basic Data Set were used to retrospectively analyze hospital discharge data with a diagnosis of asplenia from 1997 to 2021. A total of 132,257 patients with asplenia (splenectomized/non-splenectomized) were identified from the Spanish database. Among the cases, 177 (37.5%) patients with splenectomy and 295 (62.5%) patients without splenectomy developed IPD. The clinical presentations (non-infection vs. infection) did not significantly differ between the two reference groups, except for patients with COPD, rheumatoid disease, AIDS, other neurological disorders, metastatic cancer, and drug abuse. The risk factors for IPD were also more frequently reported in patients without splenectomy (p < 0.001) and with comorbidities (p = 0.005). The study of patients with asplenia provides relevant information about the state of SP infection. This epidemiological tracking can serve to better understand the comorbidities that affect them, the risk factors for the disease, the prediction of antibiotic use, and vaccination in public health, among other factors.
A Deep Learning Approach for the Automated Classification of Geomagnetically Induced Current Scalograms
Authors: Aksenovich Tatyana , Selivanov Vasiliy
Published: January 2024

During geomagnetic storms, which are a result of solar wind’s interaction with the Earth’s magnetosphere, geomagnetically induced currents (GICs) begin to flow in the long, high-voltage electrical networks on the Earth’s surface. It causes a number of negative phenomena that affect the normal operation of the entire electric power system. To investigate the nature of the phenomenon and its effects on transformers, a GIC monitoring system was created in 2011. The system consists of devices that are installed in the neutrals of autotransformers at five substations of the Kola–Karelian power transit in northwestern Russia. Considering the significant amount of data accumulated over 12 years of operating the GIC monitoring system, manual analysis becomes impractical. To analyze the constantly growing volume of recorded data effectively, a method for the automatic classification of GICs in autotransformer neutrals was proposed. The method is based on a continuous wavelet transform of the neutral current data combined with a convolutional neural network (CNN) to classify the obtained scalogram images. The classifier’s performance is evaluated using accuracy and binary cross-entropy loss metrics. As the result of comparing four CNN architectures, a model that showed high GIC classification performance on the validation set was chosen as the final model. The proposed CNN model, in addition to the main layers, includes pre-processing layers and a dropout layer.
Earthquake-Tolerant Energy-Aware Algorithm for WDM Backbone Network
Authors: Noitsis Dimitrios , Beletsioti Georgia A. , Valkanis Anastasios , Kantelis Konstantinos , Papadimitriou Georgios , Nicopolitidis Petros
Published: January 2024

Traffic on backbone communication networks is growing significantly every year. This results in an increase in both energy consumption and the carbon footprint they leave on the environment. As a response, research efforts are focused on reducing energy consumption in telecom networks. Wavelength division multiplexing (WDM) optical networks are key for addressing rising bandwidth demands in backbone networks, but this leads to a concurrent surge in energy usage. Additionally, regions with high seismic activity risk damage to backbone networks from earthquakes, causing significant bandwidth loss and service disruptions. This paper aims to reduce the energy consumption in a backbone network by implementing an algorithm that optimizes energy efficiency while preserving network connectivity and resistance to earthquake phenomena. The proposed algorithm redesigns and modifies a backbone network by deactivating the unnecessary links without affecting the network performance. The scheme is extensively evaluated through simulations using real seismic data from the Geodynamic Institute of the National Observatory of Athens, confirming earthquake resilience and energy efficiency goals, with an energy saving of up to 9% compared to existing solutions.
Isolation and Characterization of Starch from Different Potato Cultivars Grown in Croatia
Authors: Kovač Mario , Ravnjak Boris , Šubarić Drago , Vinković Tomislav , Babić Jurislav , Ačkar Đurđica , Lončarić Ante , Šarić Antonija , Bulatović Vesna Ocelić , Jozinović Antun
Published: January 2024

Starch is a polysaccharide that is widely used in food and other industries; therefore, due to its great potential, it is attempted to be maximally isolated from various foods rich in starch. Commonly, potatoes are used for starch production due to the relatively high starch content in tubers, and the process itself is complex and includes several steps. The aim of this study was to isolate and characterize starch from eight potato varieties. First, the basic chemical composition of the potato samples was determined, and then the isolation was carried out under laboratory conditions. The isolated starch was air dried, then ground and sieved through a 400 µm sieve. The basic chemical composition, amylose content, starch color, swelling capacity and solubility index, clarity of starch pastes, texture of starch gels and thermo-physical properties (gelatinization and retrogradation) were determined in the obtained starch samples. The results showed that the SL 13–25 potato variety had the lowest starch content, while the Stilleto variety had the highest starch content. The content of protein, fat, ash and crude fiber was relatively low in all of the isolated starches, indicating their high purity. Also, the difference in the color of the isolated starches was difficult to see. The highest amylose content had starch from Saprodi, while the lowest was observed in starch from SL 13–25. Starch from the cv. Dartiest had the highest, while starch from the cv. Sereno had the lowest gel strength. The starch of the cv. Dartiest also had the highest clarity value. The retrogradation transition temperatures and enthalpies were lower compared to the gelatinization temperatures and enthalpies. With the increasing temperature, both the swelling capacity and the solubility index of all the samples increased. According to the obtained differences, this study confirmed the significant influence and role of different cultivars on starch characteristics.
Lightweight Super-Resolution Reconstruction Vision Transformers of Remote Sensing Image Based on Structural Re-Parameterization
Authors: Bian Jiaming , Liu Ye , Chen Jun
Published: January 2024

In recent times, remote sensing image super-resolution reconstruction technology based on deep learning has experienced rapid development. However, most algorithms in this domain concentrate solely on enhancing the super-resolution network’s performance while neglecting the equally crucial aspect of inference speed. In this study, we propose a method for lightweight super-resolution reconstruction of remote sensing images, termed SRRepViT. This approach reduces model parameters and floating-point operations during inference through parameter equivalent transformation. Using the RSSOD remote sensing dataset as our benchmark dataset, we compared the reconstruction performance, inference time, and model size of SRRepViT with other classical methods. Compared to the lightweight model ECBSR, SRRepViT exhibits slightly improved reconstruction performance while reducing inference time by 16% and model parameters by 34%, respectively. Moreover, compared to other classical super-resolution reconstruction methods, the SRRepViT model achieves similar reconstruction performance while reducing model parameters by 98% and increasing inference speed by 90% for a single remote sensing image.
On the Precursor Environments to Mountain Lee Wave Clouds in Central Iberia under CMIP6 Projections
Authors: Díaz-Fernández Javier , Calvo-Sancho Carlos , Bolgiani Pedro , González-Alemán Juan Jesús , Farrán José Ignacio , Sastre Mariano , Martín María Luisa
Published: January 2024

Mountain lee waves present significant hazards to aviation, often inducing turbulence and aircraft icing. The current study focuses on understanding the potential impact of global climate change on the precursor environments to mountain lee wave cloud episodes over central Iberia. We examine the suitability of several Global Climate Models (GCMs) from CMIP6 in predicting these environments using the ERA5 reanalysis as a benchmark for performance. The dataset is divided into two periods: historical data (2001–2014) and projections for the SSP5–8.5 future climate scenario (2015–2100). The variations and trends in precursor environments between historical data and future climate scenarios are exposed, with a particular focus on the expansion of the Azores High towards the Iberian Peninsula, resulting in increased zonal winds throughout the Iberian Peninsula in the future. However, the increase in zonal wind is insufficient to modify the wind pattern, so future mountain lee wave cloud events will not vary significantly. The relative humidity trends reveal no significant changes. Moreover, the risk of icing precursor environments connected with mountain lee wave clouds is expected to decrease in the future, due to rising temperatures. Our results highlight that the EC-EARTH3 GCM reveals the closest alignment with ERA5 data, and statistically significant differences between the historical and future climate scenario periods are presented, making EC-EARTH3 a robust candidate for conducting future studies on the precursor environments to mountain lee wave cloud events.