bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of Group B Streptococcus Colonization in Pregnant Women in Iran: A Systematic Review and Meta-Analysis
Authors: Ghamari Mahsa , Siroosi Maryam , Beigverdi Reza
Published: June 2024

Introduction: Group B Streptococcus (GBS) or Streptococcus agalactiae is one of the main causes of invasive infections such as meningitis and septicemia in infants. Genital colonization with group B streptococci has been related to increased risk of premature delivery, and premature infants are at greater risk of disease. There is limited information about the prevalence of rectovaginal GBS colonization in pregnant women in Iran. The aim of the present study was investigating the prevalence of group B streptococcus colonization in pregnant women in Iran.
Methods: Information of this study was attained by searching on databases including PubMed, Google Scholar, Scopus, Web of Science and SID using relevant keywords and without time limit. Then, the studies containing the inclusion criteria were reviewed. The data were analyzed using Comprehensive MetaAnalysis software (Biostat V3). Heterogeneity between studies was investigated with the I2 index and based on the results of heterogeneity, the random effect model was implemented in order to determine the prevalence of GBS in pregnant women.
Results: Out of 231 articles, 15 articles were included in the study. The analysis of 15 studies showed that the prevalence of GBS in Iranian pregnant women was 12.2% (95% CI: 9.9-15.1).
Conclusion: In order to prevent the invasive neonatal disease, screening for GBS colonization is recommended for pregnant women in 35–37 weeks of gestation. Regarding the lack of preventive strategies for GBS infections in Iran, national guidelines should be established to guide the obstetricians, midwives, and nurses on the prevention of GBS infections.
Investigation of MIRs in Amphetamine Misusers
Authors: Soltanzadeh Hossein , Hojjati Bonab Zahra
Published: June 2024

Introduction: Drug addiction is characterized by uncontrolled drug use and recurrence of need for medication. Changes in gene expression play an important role in addictive neuroplasticity, but the mechanisms by which addictive drugs regenerate brain motive circuits are unclear. MicroRNAs (miRNAs) are a group of non-coding small RNAs that bind to the translocated regions; primers of their target mRNAs inhibit translation and suppress gene expression. This study investigated the profiles and different expression of MIR 24 and MIR 329 in the patients with amphetamine dysfunction.
Methods: This study was performed on 30 patients .of medical centers. RNA extraction was performed according to the kit. The amount of RNA extracted was evaluated by a nanodrop machine. These RNAs were then added to Poly (A) tail and then transformed into cDNA using specific primers and reverse transcriptase. Finally, their expression was quantitatively measured by qRT-PCR method compared to the control group.
Results: In the present study, the results indicated that MIR 24 gene expression was significantly increased compared to U6. The MIR 24 gene showed an increase of 9.02 (P-value: 0.049) compared to the control group in blood samples. The MIR 329 gene showed a decrease of 0.007 (P-value: 0.000) compared to the control group in blood samples.
Conclusion: The results showed that there was a significant association between miR-24 and miR-329 expression in blood samples of amphetamine users, which may be related to amphetamine abuse disorder. Used as a noninvasive diagnostic marker for the detection of amphetamine abuse disorder.
Investigating Factors Affecting Compliance of Patients Who are Candidates for Non-Surgical Periodontal Treatment Referred to Yazd Faculty of Dentistry in 2023
Authors: Rashidi Maybodi Fahimeh , Hosseini Yekani Ameneh , Raeesi Ahmadreza
Published: June 2024

Introduction: Considering the importance of periodontal supportive treatment in long-term preservation of teeth and prevention of recurrence of periodontitis, it was aimed to identify the factors affecting patients' compliance in continuing periodontal treatment.
Methods: This cross-sectional study conducted on 233 patients referred to the periodontics and oral health and community dentistry departments and were candidate for non-surgical periodontal treatment. Data were collected by researcher-made questionnaires and the association between demographic characteristics and some possible external and internal influencing factors with the patients' attendance in first follow-up was investigated.
Results: Only 39% of patients participated in the first follow-up. The patients' previous internal desire to participate in follow-up sessions had a statistically significant relationship with their compliance (P=0.001). Age, gender, education level, economic status, type of employment of patients and smoking did not show any significant relationship with following up the treatment. None of the investigated factors such as lack of time, the quality of mutual communication between the dentist and the patient, satisfaction with the treatment, providing health instructions by the dentist and explaining the consequences of not continuing the treatment to the patient did not affect the probability of the patient's adherence to continuing the treatment.
Conclusion: There is no definite factor to increase the compliance rate of patients and it is necessary to increase the patients' motivation with different intervention methods, in a way that the importance of participating in the follow-up sessions is clarified for the patients.
IMPACT OF MAJOR CRISES ON CONTAINER SHIPPING IN TÜRKİYE: THE CASE OF THE COVID-19 OUTBREAK
Authors: Toygar Arda , Yıldırım Umut
Published: June 2024

The Covid-19 outbreak is a recent major crisis with a broad and lasting impact on the economy, health, and society, rather than an immediate and temporary impact. In the first months following the declaration of the pandemic, the container shipping sector in Türkiye was impacted by restrictions and quarantine measures. During this period, there were reductions in ship calls, slowdowns in ship operations, and losses in storage and warehousing services. Although container volumes in Türkiye were less impacted than the global average, the previously stable growth trend came to a halt. This study examines the impact of the Covid-19 outbreak on container shipping in Türkiye as a case study. Relevant literature and statistical data were analyzed to provide a detailed examination of the specific impacts in Türkiye. In addition, the study aims to support national goals and increase resilience to future crises by providing recommendations for the stakeholders and national policy makers. These recommendations include the adoption of digitalization and blockchain technologies, regional expansion of maritime trade, considering storage strategies and developing logistics infrastructure.
Experimental Animal Models in Respiratory Diseases
Authors: Yıldız Gülhan Pınar
Published: June 2024

Respiratory diseases are among the leading causes of morbidity and mortality worldwide. Various animal models are used to understand the pathogenesis of these diseases and develop novel therapeutic strategies. Each model offers the opportunity to examine the multifaceted nature of pulmonary health, from common afflictions such as asthma and chronic obstructive pulmonary disease (COPD) to interstitial lung diseases. While these models provide a unique opportunity to understand normal physiology and disease pathophysiology and to test potential treatments for diseases, all animal models have inherent limitations. This review focuses on experimental models of common respiratory diseases such as asthma, COPD, and pulmonary fibrosis. The advantages, disadvantages, and translational potential to human disease of each model are discussed. Asthma models include mice, guinea pigs, and Drosophila, while elastase-induced emphysema, cigarette smoke exposure, and genetically modified mice are used for COPD. For pulmonary fibrosis, bleomycin, adenoviral TGF-β1 vector, silica, and genetically modified mice models are available. These models have provided valuable insights into disease mechanisms and aided in identifying new therapeutic targets. However, it is important to note that no single model fully recapitulates human disease, and each has its own unique advantages and limitations. Therefore, careful consideration of the translatability of findings from preclinical studies to humans is crucial.
El estudio de la primera infancia en el entorno urbano desde el paradigma de la complejidad y el enfoque enactivista
Authors: Vázquez Rodríguez Gerardo , Tristan Bernal Venancia
Published: June 2024

Esta investigación intenta reconocer y caracterizar los principales factores teóricos de corte sistémico que serían posibles para el estudio del sistema delimitado por la primera infancia y su entorno inmediato, formado por urbanizaciones contemporáneas.
Fenomenología de la transmutación en la arquitectura
Authors: Alvarado Villarreal Sarahí , Fitch Osuna Jesús Manuel
Published: June 2024

La investigación busca aportar y generar herramientas teóricas que ayuden a comprender el fenómeno de la mutación de la arquitectura en un determinado lugar a través del tiempo, considerando las migraciones, procesos de urbanización, crecimiento urbano, evolución de las culturas, y cómo estos componentes modifican el paisaje natural y construido.
AS POTENCIALIDADES DA ABORDAGEM (AUTO)BIOGRÁFICA E OS DESAFIOS EM SUA VALIDAÇÃO TEÓRICO-METODOLÓGICA
Authors: Moura Jónata Ferreira de
Published: June 2024

Este artigo tem por objetivo problematizar as potencialidades da abordagem (auto)biográfica nofazer pesquisa, assim como os desafios que ainda enfrenta no tocante a sua validação teóricometodológica. Realiza-se discussões do tipo bibliográfica e destaca-se as seguintes potencialidades da abordagem (auto)biográfica: inserção na investigação hermenêutica, dando sentido e compreendendo a experiência vivida e narrada; produção de dados empíricos em conformidade à formação das trajetórias guiadas pelas experiências; entendimento de que a narrativa é o lugar em que o humano toma forma, elabora e experimenta a história de sua vida em estrutura de texto; que o humano tem um corpo biográfico, singular-plural, que é um sujeito da formação que faz da tomada de consciência uma estratégia para (trans)formar-se. Quanto aos desafios, evidencia-se:evitar as tentativas de aproximá-la aos métodos de surveys de pesquisar; evitar a tradução dos dadoscomo uma série de informações fragmentárias, uma ilustração e, ainda, uma representatividade estatística; impedir o empobrecimento epistemológico ao sacralizar ou até mesmo romantizar as narrativas.
Риски инновационного предпринимательства в музыкальной индустрии в условиях (пост)пандемийных трансформаций медиакоммуникаций
Authors: Бояркина С.И. , Кузнецова Э.С.
Published: June 2024

В статье представлены результаты междисциплинарного исследования рисков инновационного предпринимательства в музыкальной индустрии. Стремительное развитие медиакоммуникаций и цифровизация культурной сферы, спровоцированные введением локдауна во время пандемии COVID‐19, привели к распространению в международной практике инновационных предпринимательских инициатив, разработке сервисов, которые предоставили возможности онлайн‐посещения музыкальных концертов, способствующих социальной и культурной инклюзии. В России сфера цифрового искусства только начинает свое становление: в отечественном бизнесе появляются отдельные проекты, предоставляющие сервисы по организации и продвижению виртуальной концертной деятельности. Актуальность исследования обусловлена низкой степенью изученности российских практик инновационного предпринимательства, существующих барьеров развития отрасли. Методы: на первом этапе исследования был проведен пилотажный анкетный онлайн‐опрос целевой аудитории цифровых концертов – представителей молодежи в возрасте от 16 до 30 лет (N = 291). На втором этапе – экспертные интервью с организаторами и руководителями бизнес‐проекта – стриминговой платформы LookPort, являющейся лидером интерактивного вещания и креативных стриминговых решений в России, Великобритании и странах Европы. Результаты: выявлено, что наиболее значимые коммерческие риски формируются потребителями услуг и обусловлены трудностями освоения технических особенностей новых сервисов и социально‐психологическими эффектами их использования − ограниченными возможностями интерактивного эмоционального  взаимодействия, не позволяющего аудитории ощутить причастность к происходящему, реализовать потребности в эмоциональной и физической коллективной экспрессии. Ключевыми ресурсами преодоления возникающих рисков становятся образовательные и управленческие компетенции предпринимателей, навыки применения современных маркетинговых инструментов формирования положительного пользовательского опыта.
Укрепление национальной идентичности как значимый фактор благополучия российского общества
Authors: Кокаревич М.Н.
Published: June 2024

Актуальность: усиливающиеся процессы глокализации в современном мире приводят к акцентированию на неповторимости каждого национально‐государственного сообщества, что актуализирует обращение к способам укрепления культурной самоидентичности. Методы: историко‐культурный и историко‐философский подходы, методология интерпретации и реконструкции культурных явлений как актуализаций ментального ядра этой культуры. Цель: выявить основные механизмы кристаллизации российской идентичности. Результаты: показано, что главным механизмом укрепления национальной идентичности является релевантность действий в системе «вызов–ответ» в пространстве межкультурного и межгосударственного взаимодействия, которое базируется на запрете иронизирования над фундаментальными духовно‐нравственными и государственными ценностями, на осмыслении роли ментальных доминат понимания, абсолютизма, соборности, доброты как факторов, детерминирующих становление русской и впоследствии российской культуры, на осознании их относительной изменчивости в процессе цивилизационного развития, их функционирования в качестве фильтров, задающих степень восприятия и трансформации культурно‐цивилизационных феноменов в пространстве взаимодействия государств‐культур. Другим механизмом укрепления национального достоинства становится отчетливое осознание величия многовековой истории России, роли православия как основы национальной самоидентичности, государственности, которая утверждается в соответствии с логикой: одна вера – единый народ – одна земля – единое государство.
Development, Nutritional and Storage Analysis of Pearl Millet Value-added Traditional Snacks (Namakpara, Mathri) Enriched with Jamun Seed Powder
Authors: . Savita , Beniwal Amita , Sangwan Veenu , Kawatra Asha
Published: June 2024

Background: Pearl millet and jamun seed powder were combined to develop snacks that utilize the nutritional value of pearl millet and jamun seeds as antioxidants for innovative, health-conscious options. This aligns with the demand for sustainable, nutrient-rich snacks blending traditional flavors with modern health considerations. Methods: Different formulations incorporated jamun seed powder at 20% levels. The study utilized a 9-point hedonic scale for sensory evaluation and standard procedures for nutritional analysis, including proximate, minerals, in vitro digestibility and storage fat quality assessments. Result: Jamun seed powder influenced the sensory scores, with 10% incorporation maintaining acceptability. Nutrient profiles were impacted, altering protein, fat, ash, crude fiber, calcium, phosphorus, zinc, phytic acid and polyphenols. In-vitro protein digestibility decreased, while starch digestibility remained unaffected. During storage, jamun seed products retained sensory attributes better than controls. Type I samples exhibits potential antioxidant and anti-rancidity properties, evident in reduced fat acidity and peroxide value after 90 days (143.40 to 137.25 KOH/100 gm and 14.33 to 13.42 meq/1000 g of fat). This study enhances nutritious and sustainable snack development, offering consumers gluten free indulgence in traditional flavors with added health benefits.
Barriers to Healthcare for Transgender Individuals
Authors: Nelson Lisa A. , Shurpin Kathleen
Published: June 2024

Background:Transgender (TG) clients experience provider bias, erasure, refusal to treat, and violence.Objective:The purpose of this article is to identify barriers to healthcare for TG individuals and discuss recommendations for providers treating this population.Methods:Literature review of prime research was conducted using the Whittemore and Knafl methodology (2005).Results:Evidence suggests that barriers to TG healthcare include lack of provider TG knowledge and trans sensitivity, lack of provider communication, and lack of emotional and physical safe healthcare environments.Conclusions:TG clients face barriers to accessing healthcare, and specific recommendations to improve provider practice will decrease these barriers.Implications for Practice:Lack of provider education affects TG individuals accessing quality healthcare. Recommendations to improve provider practice are essential to improve care.
Improving Diabetic Care Through Education and Innovation
Authors: Williamson Riki J. , Powell Renea , Shepherd Andrea K.
Published: June 2024

Background:Despite the innovative advancements in diabetes care, providers may not recognize patients with type 2 diabetes mellitus (T2DM) who qualify for a continuous glucose monitoring (CGM) device or the benefits of a telemedicine program for improving self-management behaviors.Objective:This quality improvement (QI) project aimed to determine if an advanced practice registered nurse (APRN)-led telemedicine program using CGM could improve glycemic control and self-management in patients with insulin-dependent T2DM.Methods:A 6-week telemedicine program was developed and implemented using the CGM’s time-in-range to deliver patient-specific education. Clinical metrics were collected at each visit. All patients completed a pre- and postintervention Diabetes Self-Management Questionnaire-Revised (DSMQ-R) survey.Results:A repeated measures analysis of variance revealed that the telemedicine program had a statistically significant impact on time-in-range outcomes,F(2, 14) = 18.203,p< .001. Paired-samplesttests indicate that APRN-led education improved body mass index,t(8) = 4.232,p= .002; decreased systolic blood pressure,t(8) = 2.90,p= .010, and diastolic blood pressure,t(8) = 3.21,p= .007; and increased self-management skills as evidenced by DSMQ-R,t(8) = −5.498,p< .001.Conclusions:This QI project highlights multiple interventions for improving diabetes management in a primary care facility.Implications for Nursing:An APRN-led telemedicine program integrating CGM time-in-range data can improve glycemic control and self-management skills in patients with T2DM who administer insulin.
Aplicación de nanoquitosán-yodo en lechuga y su efecto en la biofortificación, crecimiento y rendimiento
Authors: Treviño-Ruiz Karla Stephanie , Ortega-Ortiz Hortensia , Benavides-Mendoza Adalberto , González-Morales Susana
Published: June 2024

Iodine (I) is an essential element in human nutrition, however, in plants it is considered a beneficial element. The objective of the present work was to evaluate the application of nanochitosan-iodine complexes (NPsCs-I) on the biofortification of I in lettuce, in addition to its effect on growth and yield. Foliar application of NPsCs-I complexes was carried out on lettuce plants where plant height, head diameter, dry biomass and I content were measured. The application of NPsCs-I complexes had a significant effect on the yienld, since with the application of the complex at a dose of 5 mg L-1 of KIO3, it increased by 30.8% compared to the control. The foliar application of NPsCs-I complexes can provide an alternative for biofortification of I and biostimulation of lettuce plants.
Efecto de DHA y dos extractos de plantas sobre la producción de cerdos en engorda infectados con PRRS
Authors: Angeles-Marin Alvaro Alberto , Loeza-Limon Ruben , Vicente-Martínez Jorge Genaro , Villagomez-Cortes Jose Alfredo , Mariscal-Landin Gerardo , Vega-Murillo Vicente Eliezer
Published: June 2024

Pig Respiratory and Reproductive Syndrome (PRRS) is a disease with economic repercussions for pig farmers worldwide as it causes low feed efficiency and, therefore, less weight gain in the fattening stage. The effect of dietary supplementation with docosahexaenoic acid (DHA), turmeric oleoresin and capsicum (EP, plant extracts) on the productive performance of fattening pigs and on the health of a herd affected by PRRS was evaluated. Nine-hundred and sixty fattening pigs with an initial average weight of 5.21 ± 0.065 kg was randomly assigned to one of four treatments, T1, control; T2, DHA; T3, EP; T4, DHA+EP. The variables analyzed were weight at day 70 of life (P70), weight at market (PM), daily weight gain at day 70 of life (GDP70), daily weight gain to market (GDPM), feed conversion at day 70 of life (CA70) and feed conversion at market (CAM). T2 and T4 diets exceeded the control and T3 in P70 and GDP (P < 0.05), T2 and T4 did better than the control and T3 in CA70 (P < 0.05). T2, T3, and T4 surpasssed the control in PM (P < 0.05). All pigs had antibodies against PRRS throughout the study, although pigs in the second fattening cycle showed higher IgG values for T2 and T4. The cost of production for T2, T3 and T4 was lower for GDPM, CAM and PM. In conclusion, the treatments T2, T3, and T4 were superior to the control in PM and therefore, the use of DHA and phylogens wasp cost-effective.
Central American Red BrocketDieta de Mazama temama (Kerr 1792, Artiodactyla: Cervidae) en Parque Nacional Cañón del Río Blanco
Authors: Serna-Lagunes Ricardo , Ramos-Quechulpa Lizbeth , Mora-Collado Norma , Salazar-Ortiz Juan , Ocaña-Parada Carlos de Jesús , Gastelum-Mendoza Fernando Isaac
Published: June 2024

Determining the diet of herbivores through the epidermal structures present in their excreta makes it possible to identify the plants consumed and estimate the variations at different times of the year. The objective of the study was to determine the botanical composition of the diet of the deer Central American Red Brocket (Mazama temama), in the Parque Nacional Cañón del Río Blanco (PNCRB), Veracruz, Mexico. The vegetation where the study was carried out is an evergreen tropical forest with the presence of induced vegetation. Sampling was carried out during the dry and rainy season of 2021. The plant species consumed were identified with the microhistological analysis of epidermal residues in fecal samples. The diet consisted of 18 species of plants belonging to 14 botanical families. The highest percentage of consumption was for the Solanaceae family (16.6%), followed by Arecaceae, Asteraceae, Cucurbitacea and Malvaceae (11.1% each). 66% of the plants were consumed in the dry season, and consumption increased by 34% during the rainy season, showing 100% of the plant species in the rainy season, showing 100% consumption in the rainy season.. The plants consumed were 10 herbaceous plants (55.5%), six arboreal plants (33.5%), one shrub and one grass (5.5% each); forest edge plants (BB = 44%), forest interior plants (IB = 33%) and cultured plants (CP = 23%), constituted the diet. M. temama adapted its diet to the availability and temporal and spatial distribution of plants in the habitat and based on climatic conditions (dry vs. rainy).
Efecto antifúngico in vitro de hongos endófitos de cucurbitáceas criollas de Yucatán
Authors: Montañez-De Azcué Diego , Cristóbal-Alejo Jairo , Uc-Várguez Alberto , Moo-Koh Felicia Amalia , Tun Suárez José María
Published: June 2024

Endophytic fungi are plant symbiont microorganisms, diverse and abundant in tropical regions, with great potential as biocontrol agents of agricultural fungal diseases. The objective of the present work was to evaluate in vitro antifunfal activity of endophytic fungi associated with creole cultivars of Cucumis sativus and Lagenaria siceraria from Yucatán. The endophytic strains were isolated and identified from different organs, to be subjected to dual confrontations and antibiotic tests. Twenty species with antifungal effects against Corynespora cassiicola, Colletotrichum truncatum and Fusarium equiseti were identified, obtaining inhibition ranges of 17.72–100%, 16.51–91.55% and 4.64–91.89%, respectively. Aspergillus flavus, Lasiodiplodia pseudotheobromae and Trichoderma longibrachiatum exhibited the highest percentages of inhibition against the three phytopathogens. Likewise, these three species of endophytes demonstrated an antibiotic effect in their extracts, mainly inhibiting the growth of F. equiseti by up to 46.46%. The L. pseudotheobromae strain has characteristics that give it potential as an antifungal agent, so its applications and growth conditions should continue to be explored. This work represents a first effort to understand the diversity of endophytic fungi in native crops in the region.
Productividad y calidad de pasto Mulato II (Urochloa híbrido) solo y ensilado con subproductos agroindustriales
Authors: Martínez-Hernández María Fernanda , Garay-Martínez Jonathan Raúl , Ventura-Ríos Joel , Estrada-Drouaillet Benigno , Limas-Martínez Andrés Gilberto , Joaquín-Cancino Santiago
Published: June 2024

The use of silage is considered as a feeding strategy in animal production systems with ruminants during dry periods. The objective was to evaluate the yield and nutritive value in forage and silage of Mulato II grass (Urochloa hybrid) and two additives, at different regrowth ages. Ages of 3, 6 and 9 weeks and additives (orange peel and molasses) were evaluated in silages: 1) Mulato II (ME); 2) Mulato II + orange peel; 3) Mulato II + molasses and 4) Mulato II + orange peel + molasses. The variables were: yield (kg ha-1) of total dry matter (TDM) and by morphological component, plant height (PH, cm), leaf area index (LAI), CP, NDF, ADF and lignin in forage and silage; pH, brix degrees and DM (%) in silage. When the forage was harvested at nine weeks of regrowth, the highest DM yield was obtained (7 508 kg ha-1), while the CP content was higher in week three of regrowth (201 g kg-1), exceeding by 10 and 29% that found in the sixth and ninth weeks. The silages with additives presented the highest CP values and the lowest values of ADF, NDF and pH. The higher the age of regrowth, the higher the dry matter yields, while the nutritive value decreased; however, the use of orange peel and molasses in grass silages improved the nutritive value.
Efecto nematicida del extracto de Canavalia ensiformis y su potencialización con nanopartículas contra Meloidogyne incognita
Authors: Ceballos-Ceballos Augusto Gil , Ochoa-Fuentes Yisa María , Cerna-Chávez Ernesto , Cano-García Arely , Olalde-Portugal Victor
Published: June 2024

The nematicidal effect of Canavalia ensiformis seed extract combined with silicon dioxide nanoparticles was evaluated on second instar juveniles of Meloidogyne incognita, a phytopathogenic nematode that affects tomato crops. In the first experiment, concentrations of the extract were tested at 2, 4, 6, 6, 8 and 10%, observing that the most effective concentration was 10%, with 90% mortality at 24 hours. In the second experiment, concentrations of the extract at 1.5, 2.0, 2.5 and 3.0% were combined with silicon dioxide nanoparticles at 0.06, 0.08, 0.10, 0.12 and 0.14%, where the most effective was 1.5% extract with 0.14% nanoparticles, which showed a mortality of 94% at 72 hours. These results suggest that the combination of C. ensiformis extract with NP's can be a strategy for the management of M. incognita in tomato crops
PROTECTION OF MINORITY SHAREHOLDERS FROM FRAUD IN LIMITED LIABILITY COMPANY DIVIDEND DISTRIBUTION
Authors: Hartanto Stefanie
Published: June 2024

This research investigates the potential fraudulent actions carried out by majority shareholders and other corporate organs in the context of stock distribution. The primary focus is on the continuity of practices that may disadvantage minority shareholders and undermine the legal protections they should receive. Majority shareholders, often wielding significant influence in the General Meeting of Shareholders (RUPS), may exploit their power to manipulate decisions related to stock distribution. The presence of a quorum that can be achieved without the participation of minority shareholders increases the risk of fraud in this process. The aim of this research is to identify various fraudulent actions that may occur in stock distribution by majority shareholders and related corporate organs. Using a legal analysis approach and case studies, this research also explores ways in which minority shareholders might prevent or respond to fraudulent actions. Furthermore, the research examines the extent to which Law No. 40 of 2007 concerning Limited Liability Companies (UU PT) provides a legal basis to prevent and respond to fraudulent actions in stock distribution. Practical implications of potential fraud are analyzed to provide recommendations that can strengthen legal protections for minority shareholders. This research is expected to contribute to a deeper understanding of the dynamics of fraud in stock distribution, outline the legal challenges faced by minority shareholders, and formulate concrete steps to prevent and respond to such fraud in companies.
PENERAPAN MODEL PEMBELAJARAN GUIDED INQUIRY BERBANTUAN PRAKTIKUM TERHADAP KETERAMPILAN PROSES SAINS SISWA PADA MATERI GELOMBANG BUNYI
Authors: Paridah Ipi , Saefullah Asep , Antarnusa Ganesha
Published: June 2024

This research aims to determine the effect of students' science process skills using the guided inquiry learning model assisted by practicum on sound wave material at SMA Negeri 6 Serang City. The research method used is quasi-experimental with a one group pretest-posttest design approach. The research results show that the average N-gain value is 0.11 in the low category for the pretest and the posttest N-gain is 0.49 in the medium category. The average percentage result on the students' science process skills observation sheet is 78.40% in the good category. Based on the research results, there is an influence of the application of the guided inquiry learning model assisted by practicum on students' science process skills in the material of sound waves.
Analysis of Income Inequality in ASEAN Countries
Authors: Anasta Akila , Sylviana Widya
Published: June 2024

This study aims to analyze income inequality in ASEAN countries. The variables in this study are income inequality as the dependent variable, FDI, GDP per capita, personal remittances, and economic openness as independent variables. The scope of this research is ASEAN countries from 2009 to 2021. This research uses panel data regression method. The estimation results in this study show that FDI and GDP per capita variables significantly affect income inequality in ASEAN. Meanwhile, personal remittance and economic openness have no significant effect.
Navigating immunotherapy for ovarian cancer: current landscape and future perspectives
Authors: Capuozzo Maurizio , Ferrara Francesco , Cinque Claudia , Farace Stefania , Lauritano Domenico , Ottaiano Alessandro
Published: June 2024

Ovarian cancer (OC) is the leading cause of death related to gynecologic malignancies, with recurrence occurring frequently despite significant advances in surgical interventions and chemotherapy. Therefore, novel therapies are necessary to improve the long-term prognosis of the disease. Immunotherapy holds promise in OC treatment by harnessing the potential of the immune system to combat neoplastic cells. The effectiveness of immunotherapy has been demonstrated in numerous cancers and subsequently integrated into clinical practice. However, despite initial preclinical findings suggesting an immunogenic microenvironment in OC, immune checkpoint inhibitors have not shown significant outcomes in clinical studies thus far. Further investigation is needed to fully understand the role of immunity in OC and to develop more effective therapeutic strategies, including combinatorial approaches and the identification of predictive biomarkers for more accurate patient selection for immunotherapy.
Looking into EFL Students’ Intercultural Awareness and Its Relation with Varying Social Media Exposure and Reading Ability
Authors: Erlangga Fajar , Anam Syafi’ul
Published: June 2024

With explosive growth of technology and globalization, seeing vastly different culture has become part of our daily life as seen in social media. Students’ social media exposure is closely related to their reading activity. Thus, great reading ability leads to great intercultural awareness. This study aimed to investigate EFL students’ intercultural awareness and its relation with varying social media exposure and reading ability. The quantitative study employed ex-post-facto design, with participation of 183 EFL students purposively recruited from Informatics Study Program in a private univerisity in Jakarta, Indonesia. The data collected using online questionnaires and reading tests were analyzed using SPSS 27. With this software, descriptive statistics were made to compare means, percentages, and standard deviations of students’ intercultural awareness. Paired-samples t-tests were run to find out a significant difference in participants’ intercultural awareness by varying social media use and reading ability. The results revealed EFL students’ high intercultural awareness with no significant difference found in students’ varying social media use and with a significant difference found in students’s varying reading ability. In conclusion, EFL students’ intercultural awareness is influenced significantly by their reading abilities rather than their social media exposure.
Masculinity of Arthur Dismmesdale in the Novel the Scarlet Letter by Nathaniel Hawthrone
Authors: Yanti Cita Hikmah , Pane Chairunnisah
Published: June 2024

Finding masculinity in a character represented in a novel enables to investigate more to understand social behavior as social issue in personal or in a certain community. This study aims to find the masculinity in the character of Arthur Dismmesdale, a puritan priest in the novel of the scarlet letter that attract the writer to identify the uncommon manner of a male character. His character also viewed as one of influencing character who undergo social and psychological traits into the story which led the other main character took the blame on his behalf. This study was researched descriptively by reducing data and data grouping based on the problem studied. Data were taken from words and sentenced in the novel then describe and explain of character’s personality using Sigmund Freud Psychoanalysis that is id, ego and analyzing Masculinity. Arthur Dimmesdale, A concealed sinner, has a very complicit nature in masculinity, this is due to his inability to be a responsible towards his evil deeds. The character was indicated as dynamic character, He cursed himself for his silence and cowardice yet changed structurally during the story and complexed the whole story.
Comparison of Storability and Sensory Assessment of Wet Noodles with the Addition of Melinjo Leaf Extract (Gnetum gnemon L) as a Natural Preservative
Authors: Lestari Ayu Wiji , Akhmad Mutohhar  , Akhmad Faried Yusuf  , Iffah Muflihati  , Sari Suhendriani
Published: June 2024

Wet noodles are raw noodles that require cooking by boiling in boiling water before consumption. The water content in wet noodles ranges from 52-60%. High water content causes wet noodles cannot be stored for a long time. One of the natural ingredients that can be used as a preservative is melinjo leaves. The purpose of this study was to determine the effect of natural preservatives from melinjo leaf extract on the shelf life of wet noodles. Using a one-factor completely randomized design (CRD) with different ages of melinjo leaves, namely young leaves, old leaves, dry leaves, and also a mixture of the three. The extraction process is carried out through the maceration method. The solvent used in this extraction is distilled water. From the results of the research on the shelf life of wet noodles, the best shelf life analysis was found in the treatment of young leaves, namely 24 hours, testing the water content with the results for each treatment of young leaves 54.7%, old leaves 49.07%, dry leaves 48, 8% , mix 53.8%. The color test on the brightness parameter (L) was the highest on old leaves 69.42, the redness level parameter (a) was the highest on the control 4.17 , the redness level parameter (b) was the highest on the mixture 17.28. The organoleptic test showed that the wet noodles with each treatment with the addition of melinjo leaf extract were not significantly different. The hedonic test of wet noodles was acceptable to the panelists with an average value of color 4.00, aroma 3.50, taste 3.84, texture 4.00, appearance 3.98.
El discurso mítico a partir del testimonio: comparación en dos contextos de enunciación
Authors: Gonzales Muñoz Francesca
Published: June 2024

This work proposes an analysis between the mythical discourses presented from the indigenous testimony in the colonial stage that is presented in the book Testimonies, letters and indigenous manifestos, compiled by Martín Lienhard, and the testimonial account that appears in the text From the corner of the dead of Juan Ansión. To do this, critical discourse analysis and literary historiography will be used. This analysis will allow us to recognize and compare the representation of the mythical discourse in the testimonies of the indigenous communities,
Predicting the Volume of Influence of an Underground Gas Storage Reservoir: Application to a Real-World Case in Italy
Authors: Teatini P. , Ferronato M. , Franceschini A. , Adinolfi L. , Coti C. , Mantegazzi A. , Tango G.
Published: June 2024

A methodological approach is proposed in order to define and evaluate the rock volume surrounding an underground gas storage (UGS) reservoir that is potentially subjected to a stress perturbation due to the storage activities. The analysis is based on a coupled computational modeling approach combining flow dynamics with geomechanics in the reservoir. Long-term records of injected and produced gas volume and pore pressure are used to calibrate a 3-D fluid-dynamic reservoir model, which is enlarged to the active surrounding aquifer to evaluate the extent of the propagation of the pressure variation. A multi-year detection of the land motion above the reservoir can lead to the development of a reliable geomechanical model of the UGS site, similarly to the procedure developed by Teatini et al. [2011] and Janna et al. [2012], including the prediction of the mechanics of the faults possibly intercepting the investigated rock volume. The mechanics of faults is simulated by a fully implicit algorithm by means of recent computational strategies based on Lagrange multipliers [Franceschini et al., 2020, 2022a,b]. The combined action of the fluid-dynamic and geomechanical models can predict the propagation of the stress disturbance generated in the reservoir and its surroundings during the cyclic injection-extraction process. The analysis of the propagation of the stress disturbance during UGS activities allows to define the rock volume surrounding the reservoir that is potentially affected by the mining operations. The definition of this volume has a twofold motivation: (i) to identify the region where the monitoring program should be focused during the execution of the UGS activities; (ii) to exclude those occurrences, such as micro-seismic events located outside the identified volume, that cannot be related with the UGS activities.
Pipelines for CO2 Transport: Verification and Control of Running Shear Fracture Failure Mode
Authors: Canestrari A. , Torselletti E. , Di Felice A. , Mosci E. , Masi O.
Published: June 2024

Scope of the paper is to describe a methodology for the verification and control of the running shear fracture in offshore pipelines to be dedicated to CO2 transport. The objective is to avoid through thickness failures and running fracture which can be deleterious for the pipeline, the environment, and the people safety.

The running shear fracture failure mode is described, and a stepwise verification method is proposed. The application of the methodology includes the development of a simulation model (by means of patented software worldwide recognized for applications of hydrocarbon transport), with the aim to provide a basis for the definition of a reference temperature for the material testing (mainly Charpy impact test and Drop Weight Tear Test). A wide sensitivity has been performed considering different typical injection networks transporting high CO2-rich mixtures flow rates, injected both into shallow or deep-water reservoirs, at different initial operating conditions along the pipelines and different mixture compositions. The model development includes also a thermodynamic characterization suited for CO2 mixtures according to the most recent findings.

The methodology and the predictive tool are considered suitable to describe the CO2 liquid isentropic decompression and conservatively estimate the minimum temperature reached along the pipeline during a running shear fracture event. The results show that, during the crack propagation, the fluid temperature in the pipeline sections next to the rupture running tip are maintained higher than critically very low values for material embrittlement, i.e. higher than ductile to brittle material transition temperature. Different decompression behaviors have been found, based on the initial operating conditions and depending on if injection is performed into shallow or deep-water reservoirs. For all the studied cases, issues relevant to the brittle propagation of the fracture is expected only locally at the start of the leakage but not seen by the running fracture eventually started.

In order to compensate the limited experience of operations of CO2 pipelines and the lack of large full scale tests, a simulation model has been developed, combined with the available theory of the running shear fracture mechanics, with the challenge to predict the temperature and pressure trend along the pipeline during a running shear fracture event and with the main objective to rationalize the design of CO2 transportation.
Effects of Cyclic Salt Precipitation on CO2 Injectivity: From Pore-Scale to Near-Wellbore
Authors: Fogden A. , Bollermann T. , Barreto Y. , Kowollik P. , Behr A. , Burachok O.
Published: June 2024

The rate and severity of potential loss of CO2 injectivity in saline aquifers due to brine dry-out and salt accumulation near-wellbore is one of the main uncertainties in CCS project planning. Default parameters implemented in commercial reservoir simulators overestimate the degree of salt precipitation and resulting permeability impairment. The current study used lab and digital core analyses of Berea sandstone to estimate the petrophysical and dynamic properties for adjustment of predicted precipitation and flow reduction in reservoir simulation models of intermittent CO2 injection with aquifer drive.

A set of 23 core plugs were subjected to repeated brine infiltration and drying for varying cycles and drying methods, and characterized by dried-state measurements of helium porosity, Klinkenberg permeability and mercury intrusion capillary pressure, plus non-destructive 3D X-ray imaging. In early cycles, permeability showed a gradual linear decrease with porosity loss, followed by a much steeper decline over later cycles, due to preferential accumulation of salt near the end faces. The plug-scale 3D porosity map was used to history match the flow experiments, to remove these end-effects from the salt-blocking porosity-permeability trend and generalized Kozeny-Carman exponent. High-resolution 3D imaging of a Berea subsample through an analogous sequence of small-scale brine infiltration-drying experiments was used to visualize the precipitated salt in pores, for pore-scale simulation of the porosity-permeability trend in the absence of larger-scale heterogeneities in salt distribution. Further, the co-flow of brine and CO2 during drainage and imbibition was also simulated in this salt-blocked image sequence, to generate curves of relative permeability and capillary pressure versus saturation of brine and dried salt. The resulting flow properties at pore- to plug-scale were integrated into a conceptual reservoir model to evaluate injectivity impairment caused by salt clogging.
Potential of Multilateral Closed Loop Geothermal Systems for Power Generation Using Water and Supercritical CO2
Authors: Khankishiyev O. , Wu Y. , Karami H. , Salehi S. , Farajli H.
Published: June 2024

The super-hot enhanced geothermal systems were simulated to generate remarkably high megawatts of electricity per well, while in practice, the extreme underground conditions proved to be challenging for long-term production operations. This paper presents a comprehensive investigation into Multilateral Closed Loop Geothermal Systems (CLGS) using water and supercritical CO2, targeting enhanced power generation in high-temperature geothermal environments up to 350°C, while eliminating production issues such as heavy corrosion and scale formation.

Focused on optimizing system performance and ensuring well integrity, the study employs advanced flow and thermal models alongside mechanical simulation models to investigate the heat production performance of CLGS under different well design and production settings and examine the behavior of casing and cement under the subsurface temperatures. By exploring multilateral well completion techniques and varying operational parameters such as the number of laterals, injection pressure, and mass flow rate, the research identifies strategies to maximize energy recovery and minimize the levelized cost of electricity.

Significant enhancements in power generation are demonstrated, particularly with the use of supercritical CO2, which despite its lower specific heat capacity, achieves higher temperature outputs at increased resource temperatures, effectively lowering electricity costs. Sensitivity analyses highlight the critical impact of well design on system efficiency, revealing optimal flow rates and the importance of insulated tubing to prevent heat loss. Structural modeling results further indicate potential failure risks due to stress concentrations at crucial lateral junctions in the well architecture. Key findings include a production temperature decline of 15-20°C after 20 years and significant economic benefits from increasing resource temperatures and the number of lateral sections. The paper underscores the potential of CLGS to significantly improve the economic and operational sustainability of geothermal power generation, offering robust insights into the strategic deployment of these systems in challenging geothermal environments.
Harnessing High-Performance Computing for Comprehensive Visualization of Large-Scale CO2 Sequestration Flow and Geomechanics Numerical Models
Authors: Cancelliere M. , Florez H. A. , Al-Shaalan T. M. , Kovalevskiy O.
Published: June 2024

As CO2 sequestration applications become mainstream and larger, more complex projects will emerge, necessitating advanced numerical simulation and visualization. This study explores using advanced high-performance computing (HPC) infrastructures to visualize complex, multi-billion-cell, large-scale numerical models in CO2 sequestration. These models incorporate detailed flow dynamics and geomechanical data, presenting new challenges in terms of scale and complexity. Our approach addresses the impracticality of relying on standard visualization tools for such huge models. The paper highlights the potential of utilizing existing HPC resources to overcome visualization challenges in large-scale CO2 sequestration numerical models, particularly those involving intricate coupled flow and geomechanics.