bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemberdayaan Kader Kesehatan dan Tutor sebaya stunting sebagai Upaya pencegahan stunting dan Pengelola Stunting Center
Authors: Elly Dwi Masita  , Uke Maharani Dewi  , Annif Munjidah  , Hinda Noviyanti  , Pratiwi hariyani Putri  , Heni Agustina
Published: March 2024

Sampai saat ini, stunting pada anak usia 3 – 5 tahun merupakan masalah kesehatan anak terbesar yang dialami oleh sebagian besar negara berkembang termasuk Indonesia. Survey yang telah dilakukan pada bulan Januari 2023 bersama petugas kesehatan setempat bahwa dari 170 balita 30 mengalami gizi yang buruk berupa berat badan kurang sejumlah 18 balita dan 12 balita terindikasi stunting dengan orang tua yang memiliki status ekonomi rendah. Tujuan umum kegiatan ini terfokus pada pencapaian kemandirian kesehatan melalui mendirikan pusat informasi dan fasilitas tata laksana stunting yang dikelola oleh kader kesehatan sebagai upaya mencegah peningkatan prevalensi stunting sekaligus sebagai fasilitas peningkatan pendapatan keluarga yang memiliki anak dengan resiko masalah gizi, keluarga yang terindikasi stunting melalui stunting center. Metode kegiatan menggunakan pendekatan assasement based community development melalui seminar, pelatihan dan pendampingan. Instrumen menggunakan kuesioner dan cek list. Indikator ketercapaian adalah tingkat pengetahuan, tingakat ketrampilan dan pendapatan keluarga yang memiliki bayi dan balita beresiko terjadina gizi buruk dan stunting. Sasaran mitra adalah 55 kader kesehatan dan 55 ibu yang memiliki bayi dan balita yang berusia 5 tahun di wilayah Sidoarjo. Hasil dari kegiatan ini didapatkan adanya perbedaan mean pada masing- masing indikator capaian tingkat  pengetahuan sebesar 66.6. ketrampilan pengelolaan bahan makanan sebesar 66.2, ketrampilan kewirausahaan berbasis kesehatan 64.3 serta pada indikator pendapatan keluarga sebesar 1.63 dan  hasil uji mean whitney  dengan sig= 0.001. Metode pendekatan assasement based community development melalui seminar, pelatihan dan pendampingan efektif dalam mengubah tingkat pengetahuan,persepsi dan perilaku kader kesehtan dan ibu- ibu yang memiliki bayi dan balita dalam pemenuhan gizi  serta peningkatan ekonomi keluarga sebagai bentuk dukungan pada program penurunan stunting, ketahanan pangan keluarga sekaligus ketahanan ekonomi keluarga
Simulations for the Susceptible-Exposed-Infected-Recovered (SEIR) Model in the Forecast of Epidemic Outbreak
Authors: Liu Mei Feng , Boo Hui Ling
Published: March 2024

Mathematical modelling based on the compartmental Susceptible – Exposed – Infected - Recovered (SEIR) model is proposed in this paper to study the pandemic outbreak. In addition, simulations from both the deterministic approach as well as the stochastic approach are implemented to validate the present study. Among each state, the transitions between different categories are simulated by using various graph models including the complete graph, the steady Erdos-Renyi graph, as well as the varying Erdos-Renyi graph. The related parameters for the SEIR model are chosen from available literature and the effect of some other factors such as the inflow or outflow of travellers in a city as well as the impact of vaccination rate is explored. Furthermore, the difference between the simulation results coming from the deterministic SEIR model and the stochastic SEIR one is examined to check the availability of the present simulation. It is found that, the stochastic simulation based on the complete graph is more consistent with the deterministic SEIR model.
LoRa Based IoT Enabled Sensor Networks for Plantations
Authors: Lokman Muhammad Luthfi , Chan Kah Yoong , Ting Yik Tian , Lee Chu Liang , Chung Gwo Chin , Pang Wai Leong
Published: March 2024

The integration of Wireless Sensor Network (WSN) technology with the Internet of Things (IoT) in agriculture plays a pivotal role in addressing a range of challenges and constraints faced by the sector, encompassing issues such as labour shortages, suboptimal farm management practises, and unpredictable weather conditions. In response to these pressing concerns, this study focuses on the development of WSN with IoT for agriculture, employing a spread spectrum modulation technique named the Long Range (LoRa) module. By leveraging LoRa devices and wireless radio frequencies, this technology serves as a versatile platform for delivering wireless, long-range, and energy-efficient communication to support small and medium-sized agricultural operations. These operations often lack adequate technological assistance due to factors such as limited expertise and the high costs associated with cutting-edge agricultural technology. The research undertakes a comprehensive exploration, involving LoRa parameter testing, Line-of-Sight evaluations, Non-Line-Of-Sight (NLOS) simulations, and sensor calibration, to assess the efficacy of LoRa-based IoT-enabled sensor networks within plantation environments. The overarching objective of this research endeavour is to provide valuable insights that contribute to the optimisation of agricultural practises through streamlined IoT solutions. By implementing practical and cost-effective strategies, the local agricultural sector stands poised to achieve seamless strides in both sustainable and efficient food production.
The Design of Low Power Op-amp for Biomedical Application
Authors: Nasir Ameerul Asyraf , Lee Chu Liang , Chan Kah Yoong , Lee Lini , Chinnaiyan Senthilpari
Published: March 2024

This work presents a low-power operational amplifier (op-amp) circuit design which optimized and tailored specifically for biomedical circuit application in low power environment. The proposed op-amp design incorporates the folded cascode differential amplifier technique with a low voltage supply 1.2 V, utilizing current biasing, current mirrors, and adopted low-power circuit topologies. AC and DC analysis are carried out to analyse the performance of the proposed design. Extensive simulations executed using industrial standard EDA tool have validated the circuit design, and demonstrated a gain of 70.94 dB, UGBW of 4.90 MHz, GM of 52.70 dB, PM of 82.02 degrees, PSRR of 82.77 dB, CMRR of 100.78 dB, and total power dissipation of only 28.07 mW. Low power consumption is essential for biomedical circuit applications, and the result shows a significant power reduction without compromising other performance parameters. The proposed op-amp circuit design is suitable to be implemented in low-power and high-performance biomedical devices.
A Short Review: Photocatalysis As An Alternative Method for POME Treatment
Authors: Hansamali Prathibha Sellahewa , Yang Evyan Chia Yan , Zakaria Sarani
Published: March 2024

The liquid waste produced due to palm oil processing is called palm oil mill effluent (POME). It is challenging to manage because of its high production and inadequate treatment. The discharge of raw POME into the environment will result in multiple detrimental effects and environmental pollution. This short review compares the conventional treatment methods in Malaysia, which are the ponding system for the treatment of POME and the open or closed digesting tank. These systems are unable to achieve the standards set by the Department of Environment (DOE) of Malaysia. Photocatalysts, which are well-known as catalysts in the decomposition of organic contaminants, are suggested as an alternative method for POME treatment. The viability of using photocatalytic technology to remediate POME waste is discussed in this short review. The advancement and improvement of the nanoparticle system for POME treatment are identified based on past studies. It is aimed at providing readers with a clear comparison of conventional POME treatment methods and information on photocatalysis as an alternative POME treatment method.
The Application of Weighted Ranking Method Using Combination of ROC and CPI to Select Eligible Family for Keluarga Harapan Program Aids
Authors: Laswi Aishiyah Saputri , Ulvah Ulvah , Dasril Dasril
Published: March 2024

The Keluarga Harapan Program (KHP), a financial assistance, is a program launched by the government to deal with poverty in various regions of Indonesia by conducting direct surveys and collecting data on disadvantaged families in each region. However, the issue is that many recipients do not meet the appropriate criteria or are not categorized as recipients. The Composite Performance Index and Rank Centeroid algorithms are a solution in the selection process for the recipients for the KHP by carrying out the analysis and comparison stages of whether they are categorized as KM (Disadvantage Families) through several stages. The results obtained based on analysis for recipient selection with a minimum performance index coverage value of 70% can be categorized as eligible to receiv assistance. In this study, 50 KM data samples were taken with the highest assessment value 128.41. In the top tenth ranking of the highest score from the 50 data held indicated that they were truly entitled to receive PKH KM financial assistance. Before using this method, only around 40% was eligible recipients.
The Determination of Dawn Time through Image Processing Camera
Authors: Ramza Harry , Yudhanto Tossa Hario , Sugiharto Dedy , Ulum As’ad Syaifudin , Mujirudin Mohammad , Roza Emilia , Ab-Rahman Mohammad Syuhaimi , Saksono Tono , Md Khir Mohd Haris
Published: March 2024

Determining the early time prayer is very fundamental for Muslims as it directly relates to the legal requirements of prayer. Prayers are not performed whenever we want, but rather there is a determination of the beginning and end of the prayer time as a guideline for Muslims to carry it out. The Indonesia government sets standards for Muslims to perform the dawn prayer service, by precisely determining the degree of the emergence of the dawn of Sadiq by -200. This study aims to compare the determination of the government's dawn time using different sensors, specifically drone cameras as image sensors. Drones were chosen due to their several advantages. The data generated by the drone is in the form of photos, which are subsequently processed using digital image processing software, called image-J. The data obtained are in the form of mean and standard deviation. All data collected in 1 day is recorded using Excel to form a graph of data which is then carried out by a polynomial approach to find out the cutoff point as the beginning of the dawn of Sadiq which indicates the start of dawn. The method used in this research is using the 4th order polynomial approach and the Sarrus method and the data obtained is the mean value and standard deviation. The conclusions obtained in the image analysis research are that the government's dawn time is 15 minutes too fast, the standard obtained in this study is -14.98° and unlike 2D SQM data, 3D drone data results in more accurate data analysis.
Cloud-Based Realtime Decision System for Severity Classification of COVID-19 Self-Isolation Patients using Machine Learning Algorithm
Authors: Sugiono Bhima Satria Rizki , Hadi Mokh. Sholihul , Zaeni Ilham Ari Elbaith , Sujito Sujito , Irvan Mhd
Published: March 2024

The global impact of the COVID-19 pandemic has been profound, affecting economies and societal structures worldwide. Indonesia, with a high caseload, has encountered significant challenges across various sectors. Virus transmission primarily occurs through physical contact, and the surge in active cases has strained hospital capacities, leading to the hospitalization of only severe cases. The remaining patients receive home telecare, but some experience sudden health deterioration with fatal consequences. To address this issue, this study proposes a remote outpatient care system utilizing Internet of Things (IoT) technology and medical electronics. This integrated system aims to provide an effective response to the COVID-19 pandemic. The research includes a comparative analysis of three machine-learning algorithms: decision tree, gradient tree boosting, and random forest for the classification of COVID-19 patients. The results reveal that the random forest algorithm outperforms the others with an accuracy rate of 70%, as compared to 67% for the decision tree and 62% for the gradient tree boosting algorithm. This integrated system not only addresses immediate healthcare delivery challenges but also offers data-driven insights for patient classification, thereby enhancing the effectiveness and reach of medical interventions
Nhân tố ảnh hưởng đến tính trung thực của thông tin trên báo cáo tài chính của các doanh nghiệp niêm yết ở Việt Nam
Authors: Phạm Thu Huyền , Nguyễn Thị Xuân Hồng
Published: March 2024

Nghiên cứu này được thực hiện để xem xét các nhân tố ảnh hưởng đến tính trung thực của thông tin trên báo cáo tài chính của doanh nghiệp niêm yết trên thị trường chứng khoán Việt Nam giai đoạn 2010-2022. Biến phụ thuộc là Tính trung thực của thông tin trên báo cáo tài chính (gọi tắt là tính trung thực của báo cáo tài chính) được đo lường thông qua chênh lệch lợi nhuận trước và sau kiểm toán, các biến độc lập bao gồm quy mô hội đồng quản trị, quy mô ban kiểm soát, đòn bẩy tài chính, kiểm toán độc lập và cấu trúc sở hữu. Bằng phương pháp hồi quy tuyến tính, kết quả nghiên cứu cho thấy tính trung thực của báo cáo tài chính của các công ty niêm yết ở Việt Nam bị ảnh hưởng bởi quy mô ban kiểm soát, đòn bẩy tài chính, quy mô vốn và kiểm toán độc lập. Từ kết quả nghiên cứu, bài viết đã đưa ra một số thảo luận và đưa một số khuyến nghị cho các bên liên quan để gia tăng tính trung thực của báo cáo tài chính của các doanh nghiệp niêm yết ở Việt Nam.
DOMINANT PARADIGMS OF PUNISHMENT AND OTHER COERCIVE MEASURES OF CRIMINAL LAW IN THE CONTEXT OF THEIR DEVELOPMENT
Authors: Sych Konstantin
Published: March 2024

The article is devoted to the problem of the development of criminal punishment and other measures of a criminal-legal nature, which is considered through the prism of the method of the dominant paradigm. Special attention is paid to modern paradigms of criminal punishment and other measures of a criminal-legal nature. At the same time, the author notes that the Russian system of punishment and other measures of a criminal-legal nature has come to a period of its development, which can be called the period of paradigm shift.
THE STRATEGY OF COUNTERING THE PENITENTIARY SUBCULTURE FROM THE STANDPOINT OF SYSTEM ANALYSIS
Authors: Ponomarev Sergej
Published: March 2024

The article analyzes the prison subculture from the standpoint of systems theory. It is noted that the existence of informal strata of convicts and stable prison caste formation can be justified by the laws of synergetics, a science that explains the behavior of dissipative structures. It is shown that the main characteristics of a self-organizing system are characteristic of a prison society structured according to the stratification type. From the point of view of systems theory, possible models of countering the expansion of the prison subculture are considered: 1) destruction of the system; 2) the introduction of innovative elements with the formation of new laws of interaction of individual elements of the system; 3) depriving the self-organizing system of the ability to self-replication. The most acceptable choice in the existing conditions is the last option. The conclusion is made about the prospects of the current penitentiary policy of our state.
FORMATION OF THE INFORMATION SPACE AS AN ELEMENT OF UKRAINE'S HUMANITARIAN POLICY IN THE CONTEXT OF EUROPEAN INTEGRATION
Authors: PALAMARCHUK TETIANA , OPANASHCHUK PETRO , LYTVYNCHUK OKSANA , TARAN YEVHENII , KUDLACH VIRA , ANDREEV VASYL
Published: March 2024

The article examines conceptual features of information space transformations in postclassical era and its implications for Ukraine within the process of European integration of the country. The key concerns of today's information space in Ukraine in its connection with humanitarian policy are considered. The presence of the phenomenon of paradigm shift in the information space caused by war, and the necessity of changing methods of organizing this space as an element of the humanitarian policy of Ukraine, taking into account national realities and the process of European integration, is noted.
IOT MEETS THE WEB: INNOVATIVE APPROACHES IN WEB-ENABLED IOT SOLUTIONS
Authors:   Bell Media, Montreal, QC, Savani Nilesh
Published: March 2024

The rapid convergence of the Internet of Things (IoT) and web development is ushering in a new era of technological innovation. This paper explores the synergistic relationship between IoT and web technologies, highlighting innovative approaches and solutions in IoT-web integration. Key areas of focus include real-time data handling, enhanced user experience design, scalable architectures, and advanced security measures. The paper also delves into emerging technologies such as AI, ML, blockchain, and edge computing, examining their role in enhancing IoT web applications. Through case studies in smart home systems, healthcare monitoring, and industrial IoT solutions, the paper illustrates practical applications and the transformative impact of these integrations. The paper concludes with a discussion of future trends, potential innovations, and the challenges and opportunities ahead, providing insights into the evolving landscape of IoT and web development..
PREDICTING CREDIT WORTHINESS IN BANK LOAN APPROVAL PROCESS
Authors:   Department of Artificial Intelligence and Machine Learning  Kongunadu Arts and Science College  Coimbatore, India, Gomathi Dr.S , Mohanavel Dr.S ,   Department of Management Studies,  AJK College of Arts and Science  Coimbatore, India
Published: March 2024

Loans make up significant part in bank profits. In a bank, amongst large number of loan applications, it can be lengthy and challenging to choose genuine and eligible applications to approve the loan, if the process is done manually. The system was developed using Python 3.7 & its libraries and Jupyter Notebook cross-platform Integrated Development Environment (IDE). The developed system uses the machine learning algorithms - Naïve Bayes, Support Vector Machine (SVM) and XGBoost (Extreme Gradient Boosting) individually to classify the loan applications to automatically choose genuine and eligible applications. Based on average bank balance of the period and financial background, the system approves the loan amount to the predicted applicants with good credit history. The system’s performance in predicting the credit worthiness of applicants was evaluated. Naive Bayes algorithm predicted the credit worthiness with 79% accuracy, SVM algorithm with 81% and XGBoost algorithm with 84%.
Determination of Lanthanum From Antimony Waste by Spectrophotometric Method
Authors: Erkinbaeva N.
Published: March 2024

To determine the optical density of the test substance, a PE-5400UF spectrophotometer was used. Chromatograms at 600 nm were examined. The optimal conditions for carrying out photometric analysis have been determined.
Initial Biomass Effect of Azolla caroliniana Culture on Performance in the Southern Kyrgyzstan Conditions
Authors: Abdyrakhmanova Zh.
Published: March 2024

The object of the study was Azolla caroliniana Willd., collected from reservoirs of collector-drainage networks in the vicinity of Osh (Ak-Buura river basin), and also grown in laboratory conditions. To determine the initial biomass of the culture, Azolla caroliniana was grown outdoors in tray units with an area of 1 m2 of water surface, a capacity of 500 l, a depth of 50 cm and a nutrient medium prepared from chicken manure (5 g/l), which was renewed every 5 days. The initial biomass of the Azolla culture added to the trays in option I was 100 g/m2, in option II 200 g/m2, option III 300 g/m2, option IV 400 g/m2, option V 500 g/m2, option VI 600 g/m2, VII option 700 g/m2. The A. caroliniana high performance in variants III and IV is the result of its daily growth rate. As a result, the daily increase was 129.0±0.4 g/m2in option III, and 112.4±0.3 in option IV. With a low biomass (in options I and II), azolla does not have time to fully use the available nutrient medium; due to the excess nutrient medium, other aquatic plants and algae develop strongly. In this regard, the growth and development of Azolla shoots and rhizoids slows down. In the III and IV variants of the Azolla experiment, due to the complete absorption of nutrients, normal development of the root structure and shoots occurs; accordingly, the daily growth rate of raw biomass was higher than in the other variants. Thus, when growing Azolla caroliniana in field conditions or in greenhouses, it is advisable to use 300-400 g of initial biomass per 1 m2 of water surface.
Phytocenosis With the Participation of Species of the Gentiana L. Genus on the Territory of Azerbaijan
Authors: Zeynalova A.
Published: March 2024

Gentian species are found in different types of vegetation in different regions of Azerbaijan. They are found mainly in grass, forest, rocky, shrub and forest types of vegetation. These species are widespread in natural phytocenosis and play an important role in the formation of the biomass of phytocenosis. The main types of phytocenosis with the participation of gentian on the territory of Azerbaijan are described. A cenotic characteristic is given.
Poisonous Progress: Dark Fantasy, Violence, and the Fear of Change in Shirley Jackson’s We Have Always Lived in the Castle and Espido Freire’s Irlanda
Authors: Backes Heidi
Published: March 2024

This article examines Spanish author Espido Freire’s Irlanda (1998) and American author Shirley Jackson’s We Have Always Lived in the Castle (1962) as parallel narratives that make full use of gothic transgression to highlight the trauma of progress in the lives of the young narrators. The teenage protagonists of both texts create realms of dark childhood fantasy for themselves and their sisters, using violence and witchcraft against their cousins (representatives of capitalistic, heteronormative values) as a reaction to their profound fear of change – a symptom of their liminal state between the progress that is expected of them and the stasis that they prefer. The pairing of these two novels showcases the gothic obsession with the subversion of linearity, demonstrating the trauma that results from societal insistence on continual growth according to traditional social and gender norms.
Spatial Clustering Using Generalized LASSO on the Gender and Human Development Index in Papua Island in 2022
Authors: Mutaqin Ahdan Darul , Rahardiantoro Septian , Masjkur Mohammad
Published: March 2024

Equitable development from a gender perspective needs attention. Based on data from the World Economic Forum (WEF), gender equality in Indonesia has increased. Even so, the island of Papua is still very low on gender equality. It can be seen from the Gender Development Index (IPG) from the Central Bureau of Statistics (BPS), there is a considerable gap between the Papua Island IPG and the National. IPG is a comparison between the Human Development Index (IPM) for Men and Women. Based on these conditions, this study aims to classify GPI, Male IPM, and Female IPM by region using the spatial clustering method in 2022. One of the analytical methods that can overcome these conditions is Generalized LASSO. Generalized LASSO can be used on data that only has a response variable (y) for clustering. Generalized LASSO clustering uses a penalty matrix D. The formation of the D matrix is formed by giving values -1 and 1 for areas that intersect or are adjacent and a value of 0 for other areas. The best clustering for IPG uses KNN with K = 3 and the number of clusters formed is 2 clusters. The best clustering for male HDI uses KNN with K = 2 and the number of clusters formed is 8. The best clustering for female HDI uses KNN with K = 2 and the number of clusters formed is 10 clusters.
Unified Description of Dirac and Proca Equations by Entangled Spin Fields
Authors: Mitruț Alexandru Gabriel
Published: March 2024

In this paper was proved the equivalence of Dirac equation for mass $m$ with two entangled Proca fields of mass $2m$ and is proposed an equation for entangled spin fields.
Understanding Cooper Pairs through SU(2)/SO(2) and Generalizing SU(2)/SO(2) to SU(3)/SO(2)
Authors: CHEN WEN-XIANG
Published: March 2024

This article explores how a mathematical tool called SU(2)/SO(2) helps us understand the behavior of Cooper pairs, tiny electron couples responsible for superconductivity. Copper pairs consist of two electrons with opposite spins bound together by vibrations in the material. The article explains how SU(2)/SO(2) describes the electron spins and their spatial arrangement within the pairs. It shows how this tool helps predict their distribution, formation process, and magnetic properties. Ultimately, this allows us to understand superconductivity better and design new superconducting materials.
O TRADICIONAL E O MODERNO NO DISCURSO DE K-XIMBINHO
Authors: Costa Pablo Garcia da
Published: March 2024

A pesquisa visa à análise e compreensão, além da música produzida por K-ximbinho, doscontextos pelos quais passou o compositor, percebendo elementos fundamentais para a sua formação.Também propõe uma reflexão sobre a noção de significado musical e os possí­veis processos dehibridação ou outro termo que se pretenda relacionar às misturas entre os gêneros musicais Jazz eChoro, fundamentada pelo conceito de hiridação cultural e globalização de Garcia Canclini.PALAVRAS-CHAVE: K-ximbinho; hibridação; jazz; Choro.
A DANÇA DA DIÁSPORA AFRICANA NO CONTEXTO SÓCIOPEDAGÓGICO DE PORTUGAL
Authors: Pinto Maria Teresa Fabião da Silva
Published: March 2024

Esta pesquisa pretende analisar razões da prática da dança de diáspora africana no contexto socio pedagógico português. Inicialmente, apresentou-se o conceito de dança da diáspora africana, e a problemática de nomear e tratar as danças africanas fora do seu contexto autóctone. Como exemplo, utilizou-se um modelo de aula deste tipo de dança, descrevendo fases e caraterí­sticas da aula/dança. Seguidamente, compararam-se valores culturais sistematizados nas aulas em Portugal e em África, para entender que este tema abarca questões mais profundas, relacionadas com multiculturalismo, hibridismo e pós-colonialismo.
PALAVRAS-CHAVE: diáspora africana; hibridismo; pós-colonialismo.
A MÚSICA NA ESCOLA: SONS E MELODIAS QUE PERMEIAM O PROCESSO DE INCLUSÃO ESCOLAR NUMA ESCOLA DE ENSINO FUNDAMENTAL EM CURITIBA
Authors: Dias Magali , Cunha Rosemyriam
Published: March 2024

Esta pesquisa teve por objetivo estudar as atividades musicais e musicoterapêuticasdesenvolvidas em uma escola de ensino fundamental em Curitiba, a qual tem em seu quadro discentealunos de inclusão e/ou com necessidades especiais. Em virtude de estudar esses alunos, o projetodesta pesquisa foi encaminhado ao Comitê de Ética do Instituto Brasileiro de Therapias e Ensino(IBRATE) conforme protocolo nº 99/2009 e aprovado na integra conforme Of. CEP 047/09 de 25 dejunho de 2009. Para este deste estudo foram aplicados e analisados protocolos de observação, nosquais se registraram as reações fí­sicas, cognitivas e emocionais dos alunos no decorrer das atividades einterações musicais. Os resultados mostraram que a música, em virtude da mediação na comunicaçãoem musicoterapia, possibilitou formas abertas e alternativas de expressão sonora, afetiva e cognitiva.Percebeu-se ainda que tanto nas aulas de música como nas sessões de musicoterapia o desempenho e acomunicação apresentaram ní­veis significativos, porém, diferenciados.PALAVRAS-CHAVE: Musicoterapia; música; inclusão.
Processos avaliativos em larga escala e suas implicações para o Ensino de Quí­mica
Authors: Broietti Fabiele Cristiane Dias , Passos Marinez Meneghello
Published: March 2024

Neste artigo apresentamos os resultados de uma investigação que teve como objeto de pesquisa questões de Quí­mica de alguns exames avaliativos, como o ENEM e o Vestibular. Para a realização de tal estudo procuramos levantar caracterí­sticas que permitissem estabelecer relações entre os tipos de questões e as concepções de ciência e de ensino, bem como as possí­veis implicações para o Ensino de Quí­mica. Trata-se de uma pesquisa de natureza qualitativa em que se fez uso dos procedimentos da análise de conteúdo para os encaminhamentos metodológicos. Mediante as análises pudemos evidenciar questões reprodutivas e produtivas nos dois exames, com predomí­nio da primeira categoria no Vestibular, exigindo dos estudantes memorização de fatos e nomes, definições e exemplos, caracterí­sticas coerentes com o modelo de ensino denominado por transmissão-recepção. Por sua vez, nas questões do ENEM, embora também constatada a presença de questões reprodutivas, houve predomí­nio de questões produtivas, caracterizadas por apresentarem algum contexto, proporem novas situações e relacionarem diferentes variáveis, aspectos enfatizados no modelo de ensino sócio- -construtivista.
O Pibid no atendimento educacional especializado para o aluno com deficiência intelectual
Authors: Guadagnini Larissa , Duarte Márcia , Da Silva Mendes Melina Thais
Published: March 2024

As polí­ticas públicas que versam sobre a inclusão escolar, tem garantido o acesso dos alunos com deficiência na escola comum, contudo para que a permanência e apropriação de conhecimento seja garantida, muitas ações estão sendo empreendidas, dentre elas a oferta do atendimento educacional especializado (AEE) nas salas de recursos multifuncionais (SRMs). Os professores da educação especial que oferecem o AEE devem identificar, elaborar, produzir, organizar serviços e recursos pedagógicos, a fim de assegurar a estes alunos condições de acesso ao currí­culo, ou seja, criar mecanismos para sua aprendizagem, considerando as necessidades individuais. Assim, objetivou-se relatar e discutir as atividades realizadas por uma bolsista do Programa Institucional à Docência (PIBID) – Educação Especial em parceria com a professora regente do AEE, durante o segundo semestre de 2014, em uma escola de Ensino Fundamental da rede municipal da cidade de São Carlos-SP. Trata-se de um relato de experiência em que serão abordadas as caracterí­sticas do aluno com deficiência intelectual e as intervenções realizadas pela bolsista em parceria com a professora da educação especial. Como resultado considera-se que polí­ticas de iniciação à docência, voltadas para inclusão escolar, podem ser o diferencial no ensino dos conteúdos acadêmicos para os alunos com deficiência intelectual. O AEE deve não somente ir ao encontro as individualidades desses alunos, mas propor de forma prazerosa o acesso aos conteúdos escolares, de modo a despertar seu interesse nas atividades escolares.
Palavras-chave: Educação Especial, PIBID, Atendimento Educacional Especializado.
A relação força-movimento em um contexto histórico e sob a análise do PNLD
Authors: Silva Bruna Kariny , Danhoni Neves Marcos Cesar
Published: March 2024

O objetivo desta pesquisa foi identificar o conceito de força mecânica presente em seis coleções de livros didáticos de Fí­sica do PNLD 2015. Para tanto, fizemos uma revisão histórica sobre o desenvolvimento do conceito de força, de Aristóteles à Newton, passando por Philoponus, Buridan e Descartes. A partir desta revisão, definimos nossas três categorias de análise: Aristotélica, Philoponus-Buridan e Cartesiana-Newtoniana. A metodologia utilizada para análise dos dados foi a Análise de Conteúdo de Bardin. Concluí­mos a partir da análise, que as seis coleções verificadas, apresentam elementos configurativos da categoria Cartesiana-Newtoniana, e que apenas uma delas, definiu primeiramente o conceito de quantidade de movimento para depois introduzir o conceito de força a partir desta, de modo análogo ao que é estabelecido no Principia de Newton. Outra conclusão importante foi que na maioria das coleções, encontramos exemplos que discutem a influência da força de atrito no movimento de um corpo, o que é fundamental para uma boa compreensão das leis newtonianas. E ao final, sugerimos três apontamentos metodológicos que consideramos importantes para o ensino da segunda lei de Newton.
Leveraging digital agriculture for on-farm testing of technologies
Authors: Puntel Laila A. , Thompson Laura J. , Mieno Taro
Published: March 2024

The Precision Nitrogen Project (PNP) worked with more than 80 corn and winter wheat producers to inexpensively design and implement randomized, replicated field strip trials on whole commercial farm fields, and to provide site-specific testing of current nitrogen (N) technologies. This article proposes a conceptual framework and detailed procedure to select the N technology to be tested; design and implement field trials; generate, process, and manage field trial data; and automatically analyze, report, and share benefits from precision N technology. The selection of the N technology was farmer-driven to ensure a good fit and to increase the likelihood of future technology adoption. The technology selection method was called the “N tiered approach”, which consisted of selecting a technology that progressively increases the level of complexity without exceeding the farmer’s learning process or farm logistic constraints. The N tools were classified into (1) crop model-based, (2) remote sensing-based, (3) enhanced efficiency fertilizers, and (4) biologicals. Field strip trials comparing producers’ traditional management and the selected N technology were combined with site-specific N rate blocks placed in contrasting areas of the fields. Yield data from the N rate blocks was utilized to derive the site-specific optimal N rate. The benefits of current N technologies were quantified by comparing their yield, profit, and N use efficiency (NUE) to growers’ traditional management and to the estimated site-specific optimal N rate. Communication of the trial results back to the growers was crucial to ensure the promotion and adoption of these N technologies farm wide. The framework and overall benefits from N technologies was presented and discussed. The proposed framework allowed researchers, agronomists, and farmers to carry out on-farm precision N experimentation using novel technologies to quantify benefits of digital ag technology and promote adoption.
The influence of internal pressure and neuromuscular agents on C. elegans biomechanics: an empirical and multi-compartmental in silico modelling study
Authors: Essmann Clara L. , Elmi Muna , Rekatsinas Christoforos , Chrysochoidis Nikolaos , Shaw Michael , Pawar Vijay , Srinivasan Mandayam A. , Vavourakis Vasileios
Published: March 2024

The function of a specific tissue and its biomechanics are interdependent, with pathologies or ageing often being intertwined with structural decline. The biomechanics of Caenorhabditis elegans, a model organism widely used in pharmacological and ageing research, has been established as biomarker for healthy ageing. However, the properties of the constituent tissues, and their contribution to the overall mechanical characteristics of the organism, remain relatively unknown. In this study we investigated the biomechanics of healthy C. elegans cuticle, muscle tissue, and pseudocoelom using a combination of indentation experiments and in silico modelling. We performed stiffness measurements using an atomic force microscope. To approximate the nematode’s cylindrical body we used a novel three-compartment nonlinear finite element model, enabling us to analyse of how changes in the elasticity of individual compartments affect the bulk stiffness. We then fine-tuned the parameters of the model to match the simulation force-indentation output to the experimental data. To test the finite element model, we modified distinct compartments experimentally. Our in silico results, in agreement with previous studies, suggest that hyperosmotic shock reduces stiffness by decreasing the internal pressure. Unexpectedly, treatment with the neuromuscular agent aldicarb, traditionally associated with muscle contraction, reduced stiffness by decreasing the internal pressure. Furthermore, our finite element model can offer insights into how drugs, mutations, or processes such as ageing target individual tissues.
Orbital shaking conditions augment human nasoseptal cartilage formation in 3D culture
Authors: Jovic Thomas Harry , Zhao Feihu , Jia Henry , Doak Shareen Heather , Whitaker Iain Stuart
Published: March 2024

Introduction: This study aimed to determine whether a dynamic orbital shaking culture system could enhance the cartilage production and viability of bioengineered nasoseptal cartilage.

Methods: Human nasal chondrocytes were seeded onto nanocellulose-alginate biomaterials and cultured in static or dynamic conditions for 14 days. Quantitative polymerase chain reaction for chondrogenic gene expression (type 2 collagen, aggrecan and SOX9) was performed, demonstrating a transient rise in SOX9 expression at 1 and 7 days of culture, followed by a rise at 7 and 14 days in Aggrecan (184.5-fold increase, p < 0.0001) and Type 2 Collagen (226.3-fold increase, p = 0.049) expression. Samples were analysed histologically for glycosaminoglycan content using Alcian blue staining and demonstrated increased matrix formation in dynamic culture.

Results: Superior cell viability was identified in the dynamic conditions through live-dead and alamarBlue assays. Computational analysis was used to determine the shear stress experienced by cells in the biomaterial in the dynamic conditions and found that the mechanical stimulation exerted was minimal (fluid shear stress <0.02 mPa, fluid pressure <48 Pa).

Conclusion: We conclude that the use of an orbital shaking system exerts biologically relevant effects on bioengineered nasoseptal cartilage independently of the expected thresholds of mechanical stimulation, with implications for optimising future cartilage tissue engineering efforts.
Targeted drug delivery of engineered mesenchymal stem/stromal-cell-derived exosomes in cardiovascular disease: recent trends and future perspectives
Authors: Pang Jian-Liang , Shao Hong , Xu Xiao-Gang , Lin Zhi-Wei , Chen Xiao-Yi , Chen Jin-Yang , Mou Xiao-Zhou , Hu Pei-Yang
Published: March 2024

In recent years, stem cells and their secretomes, notably exosomes, have received considerable attention in biomedical applications. Exosomes are cellular secretomes used for intercellular communication. They perform the function of intercellular messengers by facilitating the transport of proteins, lipids, nucleic acids, and therapeutic substances. Their biocompatibility, minimal immunogenicity, targetability, stability, and engineerable characteristics have additionally led to their application as drug delivery vehicles. The therapeutic efficacy of exosomes can be improved through surface modification employing functional molecules, including aptamers, antibodies, and peptides. Given their potential as targeted delivery vehicles to enhance the efficiency of treatment while minimizing adverse effects, exosomes exhibit considerable promise. Stem cells are considered advantageous sources of exosomes due to their distinctive characteristics, including regenerative and self-renewal capabilities, which make them well-suited for transplantation into injured tissues, hence promoting tissue regeneration. However, there are notable obstacles that need to be addressed, including immune rejection and ethical problems. Exosomes produced from stem cells have been thoroughly studied as a cell-free strategy that avoids many of the difficulties involved with cell-based therapy for tissue regeneration and cancer treatment. This review provides an in-depth summary and analysis of the existing knowledge regarding exosomes, including their engineering and cardiovascular disease (CVD) treatment applications.
Universal basic income on blockchain: the case of circles UBI
Authors: Papadimitropoulos Vangelis , Perperidis Giannis
Published: March 2024

The paper reviews Circles UBI as an illustrative case study of implementing the idea of universal basic income (UBI) on blockchain. Circles was born out of the Gnosis Chain as a more democratic alternative to Bitcoin coupled with the ambitious political project of algorithmically distributing UBI. Backed by the Gnosis Chain, Circles Coop was founded in 2020 to implement this idea in Berlin. Examining the failure of the Berlin pilot helps us draw substantial conclusions with regard to the implementation of UBI on blockchain. UBI alone, on blockchain or not, is not enough to solve the problems its proponents argue against. UBI would be helpful as a tool if plugged into a model of production embedded into a political strategy aiming to fix key problems of current societies such as gaping inequalities and climate change. We give a snapshot here of the model of open cooperativism as a counter-hegemonic political project vis-à-vis neoliberalism. Circles UBI could plug into the model of open cooperativism as a distribution and liquidity injection mechanism to foster the transition towards a commons-based ethical and sustainable post-capitalist economy.
The causal relationship between gut microbiota and biliary tract cancer: comprehensive bidirectional Mendelian randomization analysis
Authors: Wang Kui , Wang Suijian , Qin Xianzheng , Chen Yifei , Chen Yuhua , Wang Jiawei , Zhang Yao , Guo Qiang , Zhou Chunhua , Zou Duowu
Published: March 2024

Background

Growing evidence has shown that gut microbiome composition is associated with Biliary tract cancer (BTC), but the causality remains unknown. This study aimed to explore the causal relationship between gut microbiota and BTC, conduct an appraisal of the gut microbiome’s utility in facilitating the early diagnosis of BTC.

Methods

We acquired the summary data for Genome-wide Association Studies (GWAS) pertaining to BTC (418 cases and 159,201 controls) from the Biobank Japan (BBJ) database. Additionally, the GWAS summary data relevant to gut microbiota (N = 18,340) were sourced from the MiBioGen consortium. The primary methodology employed for the analysis consisted of Inverse Variance Weighting (IVW). Evaluations for sensitivity were carried out through the utilization of multiple statistical techniques, encompassing Cochrane’s Q test, the MR-Egger intercept evaluation, the global test of MR-PRESSO, and a leave-one-out methodological analysis. Ultimately, a reverse Mendelian Randomization analysis was conducted to assess the potential for reciprocal causality.

Results

The outcomes derived from IVW substantiated that the presence of Family Streptococcaceae (OR = 0.44, P = 0.034), Family Veillonellaceae (OR = 0.46, P = 0.018), and Genus Dorea (OR = 0.29, P = 0.041) exerted a protective influence against BTC. Conversely, Class Lentisphaeria (OR = 2.21, P = 0.017), Genus Lachnospiraceae FCS020 Group (OR = 2.30, P = 0.013), and Order Victivallales (OR = 2.21, P = 0.017) were associated with an adverse impact. To assess any reverse causal effect, we used BTC as the exposure and the gut microbiota as the outcome, and this analysis revealed associations between BTC and five different types of gut microbiota. The sensitivity analysis disclosed an absence of empirical indicators for either heterogeneity or pleiotropy.

Conclusion

This investigation represents the inaugural identification of indicative data supporting either beneficial or detrimental causal relationships between gut microbiota and the risk of BTC, as determined through the utilization of MR methodologies. These outcomes could hold significance for the formulation of individualized therapeutic strategies aimed at BTC prevention and survival enhancement.
Frozen elephant trunk versus conventional proximal repair of acute aortic dissection type I
Authors: Göbel Nora , Holder Simone , Hüther Franziska , Anguelov Yasemin , Bail Dorothee , Franke Ulrich
Published: March 2024

Objective

The extent of surgery and the role of the frozen elephant trunk (FET) for surgical repair of acute aortic dissection type I are still subjects of debate. The aim of the study is to evaluate the short- and long-term results of acute surgical repair of aortic dissection type I using the FET compared to standard proximal aortic repair.

Methods

Between October 2009 and December 2016, 172 patients underwent emergent surgery for acute type I aortic dissection at our center. Of these, n = 72 received a FET procedure, while the other 100 patients received a conventional proximal aortic repair. Results were compared between the two surgery groups. The primary endpoints included 30-day rates of mortality and neurologic deficit and follow-up rates of mortality and aortic-related reintervention.

Results

Demographic data were comparable between the groups, except for a higher proportion of men in the FET group (76.4% vs. 60.0%, p = 0.03). The median age was 62 years [IQR (20), p = 0.17], and the median log EuroSCORE was 38.6% [IQR (31.4), p = 0.21]. The mean follow-up time was 68.3 ± 33.8 months. Neither early (FET group 15.3% vs. proximal group 23.0%, p = 0.25) nor late (FET group 26.2% vs. proximal group 23.0%, p = 0.69) mortality showed significant differences between the groups. There were fewer strokes in the FET patients (FET group 2.8% vs. proximal group 11.0%, p = 0.04), and the rates of spinal cord injury were similar between the groups (FET group 4.2% vs. proximal group 2.0%, p = 0.41). Aortic-related reintervention rates did not differ between the groups (FET group 12.1% vs. proximal group 9.8%, p = 0.77).

Conclusion

Emergent FET repair for acute aortic dissection type I is safe and feasible when performed by experienced surgeons. The benefits of the FET procedure in the long term remain unclear. Prolonged follow-up data are needed.
High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia
Authors: Herup-Wheeler Tristin , Shi Mingxin , Harvey Madeleine E. , Talwar Chandni , Kommagani Ramakrishna , MacLean James A. , Hayashi Kanako
Published: March 2024

Immune dysfunction is one of the central components in the development and progression of endometriosis by establishing a chronic inflammatory environment. Western-style high-fat diets (HFD) have been linked to greater systemic inflammation to cause metabolic and chronic inflammatory diseases, and are also considered an environmental risk factor for gynecologic diseases. Here, we aimed to examine how HFD cause an inflammatory environment in endometriosis and discern their contribution to endometriotic-associated hyperalgesia. Our results showed that HFD-induced obesity enhanced abdominal hyperalgesia that was induced by endometriotic lesions. Peritoneal inflammatory macrophages and cytokine levels increased by lesion induction were elevated by chronic exposure to HFD. Increased expression of pain-related mediators in the dorsal root ganglia was observed after lesion induction under the HFD condition. Although HFD did not affect inflammatory macrophages in the peritoneal cavity without lesion induction, the diversity and composition of the gut microbiota were clearly altered by HFD as a sign of low-grade systemic inflammation. Thus, HFD alone might not establish a local inflammatory environment in the pelvic cavity, but it can contribute to further enhancing chronic inflammation, leading to the exacerbation of endometriosis-associated abdominal hyperalgesia following the establishment and progression of the disease.