bluuebunny/crossref_metadata_2025 huggingface dataset:
A Remote-operated System to Map Radiation Dose in the Fukushima Daiichi Primary Containment Vessel
Authors: Nancekievill M. , Jones A. R. , Joyce M. J. , Lennox B. , Watson S. , Katakura J. , Okumura K. , Kamada S. , Katoh M. , Nishimura K.
Published: January 2018

This paper describes the development of a submersible system based on a remote-operated vehicle coupled with radiation detectors to map the interior of the reactors at the Fukushima Daiichi nuclear power station. It has the aim oflocating fuel debris. The AVEXIS submersible vehicle used in this study has been designed as a low-cost, potentially disposable, inspection platform that is the smallest of its class and is capable of being deployed through a 150 mm diameter access pipe. To map the gamma-ray environment, a cerium bromide scintillator detector with a small form factor has been incorporated into the AVEXIS to identify radioactive isotopes via gamma-ray spectroscopy. This provides the combined system with the potential to map gamma-ray spectra and particle locations throughout submerged, contaminated facilities, such as Units 1, 2 and 3 of the Fukushima Daiichi nuclear power plant. The hypothesis of this research is to determine the sensitivity of the combined system in a submerged environment that replicates the combination of gamma radiation and water submersion but at lower dose rates.
Pulse Shape Analysis and Discrimination for Silicon-Photomultipliers in Helium-4 Gas Scintillation Neutron Detector
Authors: Barker Cathleen , Zhu Ting , Rolison Lucas , Kiff Scott , Jordan Kelly , Enqvist Andreas
Published: January 2018

Using natural helium (helium-4), the Arktis 180-bar pressurized gas scintillator is capable of detecting and distinguishing fast neutrons and gammas. The detector has a unique design of three optically separated segments in which 12 silicon-photomultiplier (SiPM) pairs are positioned equilaterally across the detector to allow for them to be fully immersed in the helium-4 gas volume; consequently, no additional optical interfaces are necessary. The SiPM signals were amplified, shaped, and readout by an analog board; a 250 MHz, 14-bit digitizer was used to examine the output pulses from each SiPMpair channel. The SiPM over-voltage had to be adjusted in order to reduce pulse clipping and negative overshoot, which was observed for events with high scintillation production. Pulse shaped discrimination (PSD) was conducted by evaluating three different parameters: time over threshold (TOT), pulse amplitude, and pulse integral. In order to differentiate high and low energy events, a 30ns gate window was implemented to group pulses from two SiPM channels or more for the calculation of TOT. It was demonstrated that pulses from a single SiPM channel within the 30ns window corresponded to low-energy gamma events while groups of pulses from two-channels or more were most likely neutron events. Due to gamma pulses having lower pulse amplitude, the percentage of measured gamma also depends on the threshold value in TOT calculations. Similarly, the threshold values were varied for the optimal PSD methods of using pulse amplitude and pulse area parameters. Helium-4 detectors equipped with SiPMs are excellent for in-the-field radiation measurement of nuclear spent fuel casks. With optimized PSD methods, the goal of developing a fuel cask content monitoring and inspection system based on these helium-4 detectors will be achieved.
Advanced Multilayer Composite Heavy-Oxide Scintillator Detectors for High Efficiency Fast Neutron Detection
Authors: Ryzhikov Vladimir D. , Naydenov Sergei V. , Pochet Thierry , Onyshchenko Gennadiy M. , Piven Leonid A. , Smith Craig F.
Published: January 2018

We have developed and evaluated a new approach to fast neutron and neutron-gamma detection based on large-area multilayer composite heterogeneous detection media consisting of dispersed granules of small-crystalline scintillators contained in a transparent organic (plastic) matrix. Layers of the composite material are alternated with layers of transparent plastic scintillator material serving as light guides. The resulting detection medium – designated as ZEBRA – serves as both an active neutron converter and a detection scintillator which is designed to detect both neutrons and gamma-quanta. The composite layers of the ZEBRA detector consist of small heavy-oxide scintillators in the form of granules of crystalline BGO, GSO, ZWO, PWO and other materials. We have produced and tested the ZEBRA detector of sizes 100x100x41 mm and greater, and determined that they have very high efficiency of fast neutron detection (up to 49% or greater), comparable to that which can be achieved by large sized heavy-oxide single crystals of about Ø40x80 cm3 volume. We have also studied the sensitivity variation to fast neutron detection by using different types of multilayer ZEBRA detectors of 100 cm2 surface area and 41 mm thickness (with a detector weight of about 1 kg) and found it to be comparable to the sensitivity of a 3He-detector representing a total cross-section of about 2000 cm2 (with a weight of detector, including its plastic moderator, of about 120 kg). The measured count rate in response to a fast neutron source of 252Cf at 2 m for the ZEBRA-GSO detector of size 100x100x41 mm3 was 2.84 cps/ng, and this count rate can be doubled by increasing the detector height (and area) up to 200x100 mm2. In summary, the ZEBRA detectors represent a new type of high efficiency and low cost solid-state neutron detector that can be used for stationary neutron/gamma portals. They may represent an interesting alternative to expensive, bulky gas counters based on 3He or 10B neutron detection technologies.
The Self-Powered Detector Simulation ‘MATiSSe’ Toolbox applied to SPNDs for severe accident monitoring in PWRs
Authors: Barbot Loïc , Villard Jean-François , Fourrez Stéphane , Pichon Laurent , Makil Hamid
Published: January 2018

In the framework of the French National Research Agency program on nuclear safety and radioprotection, the ‘DIstributed Sensing for COrium Monitoring and Safety’ project aims at developing innovative instrumentation for corium monitoring in case of severe accident in a Pressurized Water nuclear Reactor. Among others, a new under-vessel instrumentation based on Self-Powered Neutron Detectors is developed using a numerical simulation toolbox, named ‘MATiSSe’. The CEA Instrumentation Sensors and Dosimetry Lab developed MATiSSe since 2010 for Self-Powered Neutron Detectors material selection and geometry design, as well as for their respective partial neutron and gamma sensitivity calculations. MATiSSe is based on a comprehensive model of neutron and gamma interactions which take place in Selfpowered neutron detector components using the MCNP6 Monte Carlo code. As member of the project consortium, the THERMOCOAX SAS Company is currently manufacturing some instrumented pole prototypes to be tested in 2017. The full severe accident monitoring equipment, including the standalone low current acquisition system, will be tested during a joined CEA-THERMOCOAX experimental campaign in some realistic irradiation conditions, in the Slovenian TRIGA Mark II research reactor.
Study and Search for Main Reason of Lung Cancers Based on Cherenkov Radiation in Environmental Radiation
Authors: Ito Hiroshi , Emoto Yusaku , Fujihara Kento , Kawai Hideyuki , Kimura Shota , Kodama Satoshi , Mizuno Takahiro
Published: January 2018

The number of lung-cancer-related death is highest among all cancers in the world, and it is increasing in Japan where population aging in progressing. The main reason for the lung cancer of non-smokers is regarded to be environmental pollution or exposure of the lung to radon in the nature. The risk of lung cancer was estimated to increase by 8 to 13% per every 100 Bq m-3 concentration of radon in the air. We observed beta rays with maximum energy of 3.27 MeV emitted from 214Bi as one of the progenies based on a detection of Cherenkov radiation. The surface radioactivity concentration of 214Bi on the sample was measured; the relation between the concentration and exposure time for the sample at the room air is researched. The behavior of the radon progenies in the air is discussed by a research for the progenies attaching on the sample after the radon decay. The inhalation of the radon progenies is not clear. Thus, to understand the behavior of progenies in the air make to clear the causal relation between the radon concentration and lung cancers.
Fiber optical dose rate measurement based on the luminescence of beryllium oxide
Authors: Teichmann Tobias , Sponner Jan , Henniger Jürgen ,   TU Dresden
Published: January 2018

This work presents a fiber optical dose rate measurement system based on the radioluminescence and optically stimulated luminescence of beryllium oxide. The system consists of a small, radiation sensitive probe which is coupled to a light detection unit with a long and flexible light guide. Exposing the beryllium oxide probe to ionizing radiation results in the emission of light with an intensity which is proportional to the dose rate. Additionally, optically stimulated luminescence can be used to obtain dose and dose rate information during irradiation or retrospectively. The system is capable of real time dose rate measurements in fields of high dose rates and dose rate gradients and in complex, narrow geometries. This enables the application for radiation protection measurements as well as for quality control in radiotherapy. One inherent drawback of fiber optical dosimetry systems is the generation of Cherenkov radiation and luminescence in the light guide itself when it is exposed to ionizing radiation. This so called “stem” effect leads to an additional signal which introduces a deviation in the dose rate measurement and reduces the spatial resolution of the system, hence it has to be removed. The current system uses temporal discrimination of the effect for radioluminescence measurements in pulsed radiation fields and modulated optically stimulated luminescence for continuous irradiation conditions. This work gives an overview of the major results and discusses new-found obstacles of the applied methods of stem discrimination.
Intercultural Hands on Projects – Experiences in Architectural Education in Asian and European Context
Authors: Hackel Marcus , Gaube Andrea , Lampe MA Sabrina
Published: January 2018

The duties of German architects include the indepth design process as well as a thorough quality supervision during the construction process with the goal of the “build success“. They are reflected in the “Hands on Projects” organized by German Universities. The best results and broadest findings come out of international and interdisciplinary cooperation and projects with participants coming from the diverse cultural background and even integrating refugees into these projects.

Students get in touch with different philosophies, attitudes, values, and approaches. They learn about intercultural communication and develop unique solutions. Different social and cultural background leads to different behavior. Not being aware of the cultural differences may lead to misunderstanding and irritation. Analysing the cause of these misunderstandings and getting knowledge about the cultural influence on architectural planning, communication and problem solving is one of the mayors tasks of these intercultural and interdisciplinary projects.

Two case studies from Thailand and Germany published in this paper show different experiences with intercultural and interdisciplinary “Hands on Projects”.
Teaching Co-Design to Promote Students’ Community Engagement
Authors: Raharjo Wiryono
Published: January 2018

The current landscape of architectural education has been predominantly based on studio teaching the mode of teaching that can be traced back in the age of French L’Ecole des Beaux Arts. It was during the Beaux Arts era that studio teaching and jury system first deve-loped, and it continues today. The approach is characterized by the use of atelier (studio) for coaching, where juniors learn from seniors and competition among students are the norm. The approach also presumes that architects are the provider of design services who think that they are more competent than their clients in solving the design problem; which is a paradox to the fact that most parts of the built environment anywhere in the world are the creation of ordinary people. In other words, ordinary people can contribute significantly to the decision making within the architectural design process. They can actually be treated as a partner of architects in designing their building, which is what Co-Design all about. This paper aims to describe the introduction of Co-Design approach in architectural design studio teaching at Universitas Islam Indonesia. The research questions this paper intends to respond: to what extent could Co-Design be adopted in architectural design teaching? What lessons have the students learned from their experience in involving people in the urban design process? The case study methods employed in this research, through which author looks at the Co- Design teaching delivery in the Architectural Design Studio 7 in the past three years. While overall result of the study shows that time limitation has constrained the students’ community engagement, most cases examined reveal that introduction of Co-Design approach has paved the way for students to understand how ordinary people contribute to the shaping of the urban built environment.
Architecture Studio Learning: Strategy to Achieve Architects Competence
Authors: Saifudin Mutaqi Ahmad
Published: January 2018

In most Schools of Architecture, Architecture Studio is at the core of the architectural learning process. In the process, students are trained to have the skills of architectonic spaces design based on the study of the site, its function, and its aesthetics. Students are also trained to have awareness and understanding about the impact of their design on the surrounding environment, both physically and socially. Also, students are trained to present their designs in various forms such as visual graphics, verbal narratives, and three dimensional model animations. Indonesian Association of School of Architecture (APTARI Asosiasi Perguruan Tinggi Arsitektur Indonesia) and Indonesian Institute of Architects (IAI - Ikatan Arsitek Indonesia) has formulated an education Standards, Curriculum, and Achievements of Architect Professional Program to be referred by Ministry of Research, Technology, and Higher Education (KEMENRISTEKDIKTI – Kementerian Riset, Teknologi, danPerguruanTinggi) as the guidance for the implementation of Architect Professional Program (PPA - Pendidikan Profesi Arsitek) in Indonesia. One of the eight recommendations is the PPA Content Standard which contains the learning for the achievement of IAI Architect Competencies through the recommended study materials. However, the recommended study materials did not indicate the activity of the Architecture Studio learning model (Final Report of APTARI Part II and IAI). Will architect’s competence be achieved if the learning process withoutarchitectural studio learning model? The formulation of the curriculum that is developed independently by the IAI recommends the learning of Architectural Studio as Professional Studio. The size of the SKS is large enough to enable someone who follows the lesson to intensively gain experience in designing the building as a real architectural work. This Architecture Studio learning model is interpreted by PPAr organizer universities with various forms, among others: (1) apprenticeship of architects; (2) supervised studios; And (3) project simulation studio. From various models of Architecture learning model mentioned above, all aim to achieve 13 Architect Competence as formulated by IAI. Which model is effective in learning the Architectural Studio mentioned above? This exploratory study would like to compare the three forms of Architecture Studio learning model to see how much the achievement of the targeted competencies by measuring the success of Competency Test activities still use the standards implemented by LPJK by involving assessors from IAI. The results of the comparison will show the compatibility of the implementation of the Architecture Studio learningmodel what is considered effective. These findings will certainly benefit the development of future PPAr implementation, especially if the Architecture Studio model can be commensurate with the studios developed by the School of Architecture in various countries, at least in the region of 21 member countries ARCASIA.
Sulapa Eppa As The Basic or Fundamental Philosophy of Traditional Architecture Buginese
Authors: Syarif  , Yudono Ananta , Harisah Afifah , Mochsen Sir Moh
Published: January 2018

In general, traditional buildings in South Sulawesi Province are built based on the hopes for better future. Therefore, the house is considered as the manifestation of the natural universe (macrocosms). House and settlements are ones of the highest cultural heritage works, in Buginese communities. The value of sacredness and robustness raises the meaning of sulapa eppa philosophy, which is considered as the philosophy to realize Buginese traditional house. The purpose of this study is to discover the philosophy of sulapa eppa that underlines the formation of Buginese traditional architecture. The elements of the house present a philosophical meaning. Panrita bola serves as the informants of sulapa eppa philosophy. This research is qualitative, descriptive and explorative methods as well as naturalistic paradigm approach. The population is traditional Buginese buildings, and the samples arepost habitation, or temporarily built Buginese traditional buildings. The sampling techniques are sampling proposed and sampling incidentally. Research location is in Soppeng regency, South Sulawesi Province. The results of this study are sulapa eppa as the basic of Buginese formation traditional architecture, either physical or nonphysical. Physically, the formations of architecture are in the form, size of proportion, and building elements. And non-physically, it also can be obtained from Panrita bola, and Lontara Bugis manuscripts.
Social Spaces Territory of Bajo Tribe’s Settlement
Authors: Syam Syahriana , Yudono Ananto , Wikantari Ria , Harisah Afifah
Published: January 2018

Kampung Bajo along the bay of Bone South Sulawesi, inhabited by Bajo tribe and Bugis tribes coexist so that there is social-cultural interaction. Since 1905 the life of the Bajo tribe has changed,they began to open themselves to relationships, initially exchange the staple for its survival. As a result of these relationships, dynamics arise in the use of space both micro space, meso and macro space in the scale of settlements, making it very difficult to see the limits of territory in the use of space. Territory deals with spaces with a certain extent where individuals or groups use and defend their exclusive territory. Seeing this, the research is important and interesting to do, focused on the concept of the territory of social space in the context of the interaction of two ethnic Bajo tribe and Bugis tribe in the form of settlement, using phenomenology method.
Singosaren As Interactive Space In Kotagede Tourism Destination
Authors: Panjaitan Irwin , Prasetiyo Moh.
Published: January 2018

The development of the area for tourism purposes should have good sensitivity related to the product to consumption aspects, where the interaction between the local community is seen as the supply (insider) produce the products, which can then be consumed by the visitor as demand (outsider). Such sensitivity can be seen in the space between the private realm and the public sphere called the interface space. Development of the area for tourism, will enhance the touristsaccessibility in exploring its uniqueness as a tourist attraction. Accessible tourist attractions can improve the degree of permeability, which can also affect the degree of privacy of local communities. Singosaren as an area that will be designed as part of the united Kotagede tourist destinations, Yogyakarta, should consider the influence of tourism activities on a daily basis of the community. Permeability study in the area with mapping method, is expected to connect local potency to the circulation pattern in the interface, by finding the street corridor that needs to be anticipated, to maintain the sustainability of tourism activities in Singosaren area.
Reading Architecture: Explorative Text-ual Reception for Architectural Education
Authors: Mirza M. , Harahap Y. , Andri Yatmo Yandi , Atmodiwirjo Paramita
Published: January 2018

This paper discusses how reading is central to the architectural practice and how it carries an immense potential for design method, it is further argued that an act of reading is important to be introduced and learned in the architectural education institution within which students learn and develop various design methods. Accordingly, to this importance, this paper proposes a discussion toward various examinations of reading of various types of text. Stressing the discussion toward the conception of reception, interpretation, and representation, this paper aims to disclose the potential of the textual reading for design development by dismantling a range of exploratory reading acts, from literal act of reading to a developed act of reading, each of which positioned text as an event rather than an object. Each of the acts of reading ex Amined in the study takes a role as a process of creative analysis and interpretation which results in a representation of received knowledge.
Cultural Assemblage as Genius Loci: Character Analysis of Medan City Center District
Authors: Hajaruddin Siregar Hari , Natalivan Petrus , Suharjono Ekomadyo Agus
Published: January 2018

The city of Medan was formed from a rapidly growing plantation industry in the 1800s. The area that was originally only a village called Medan Putri with a population of about 200 people slowly changed since the Dutch investors saw the prospect of tobacco plantations in this region (Sinar, 2006). The amount of manpower needed to manage the plantation resulted in the investors bringing labor from Java, China and also Tamil. Moving the central government of the Deli Sultanate to Medan in 1891 increasingly crowded Medan at that time. The Arabs, Mining, Mandailing, and Aceh began to arrive for trading purposes as Medan began to grow and become more crowded. The study focused on locating the genius loci of Medan City through tracing the historical meaning by adapting the method undertaken by Norberg Schultz in tracing the spirit of the place and genius loci. The result of the analysis shows the role of culture and economic background that plays a major role in the formation of the character of Medan City center. The city is formed from the history of the plantation industry as well as the diverse cultures that share the same attachment and goals in the economic field.
Generative Algorithms in Alternative Design Exploration
Authors: Gunagama M. Galieh
Published: January 2018

The improvement of design capabilities with the help of computers has been very commonly discussed recently. Many studies have presented the topic of evaluating a condition on a design proposing a form by applying an algorithmic approach. However, this is still a discourse when it comes to design exploration at the preliminary design stage, which in general, design initiation is still dependent on humans. This research seeks to bridge the existing gap by devising an algorithm that can help create alternative designs at preliminary design stage. The case scenario presented in this study is for 1 story building on sloped land. Design limitations and site conditions are the primary considerations. The discussion focused on the dynamics of the algorithm process that was arranged for the acceleration of alternative design creations.
Mapping of Affordance and Activity as the Biophilic Design Principle of Blue Lagoon Tourism Area Yogyakarta
Authors: Saptorini Hastuti , Viviani Dea
Published: January 2018

Bathing and playing in the river is not a new phenomenon for some people. But this experience creates a recreational spirit on the Tepusriver which is now better known as the Blue Lagoon. This area is a term for the settlement that is split a piece of the river in the dusun Ndalem Ngemplak Sleman. Its tributaries are clear and blue, surrounded by some springs with natural bamboo groves and old trees that invite local and around communities for recreation. The local community has anticipated it by responding to the communities’ demands as well as the recreation area. Appear sporadically“warungs”and recreational activities follow-up though not yet grown in conceptual. This paper aims to study the map of affordance and activity of previous research findings and could be used to the biophilic design to afford the health, productivity, and wellbeing in the tourism area. The method is by synthesizing the previous research findings in 2016, some relevant urban design theories, and biophilic design principle. The conclusion is paid attention to two main principles. The first principle is maximizing the utilization of existing natural properties and the existing cultural skills into its development to nourish visitors both physically and psychologically. The second principle is the Government, and Non-Government Organizations (i.e., expertise, academics, universities, investors) support, both policy and financially, in many sectors: tourism, environment, and infrastructure.
Sustainable Customized Consolidation Design of Kuin Riverside Kampong Regeneration in Banjarmasin, Indonesia
Authors: Prayitno Budi
Published: January 2018

On the one hand, the hyper-urbanization phenomenon gives numerous advancements in urban living quality, yet on the other hand, it also raises an equal amount of problems. Environmental issues come in the form of density issues, the existence of slums, floods, social inequality, and urban architectural identity. As a city with “City of a Thousand Rivers” as its brand, Banjarmasin now faces a shift in an urban architectural image from a river based city to a land-based city due to the rapid land-based infrastructure development. This resulted in the degradation of environmental and architectural quality of river-based village (kampong) settlement, the main component of Banjarmasin river front city, due to a strong paradigm shift. Kuin, a river side residential area/riverside tourist destination that is currently experiencing a degradation of environmental quality and place identity, is undergoing an urban renewal. Unfortunately, the policy approaches to urban planning that has been implemented are based on general formal guidelines; guidelines which do not take the informal nature of kampong river-side settlements, due to the lack of guidelines based on riverside place identity. This paper aims to explore the characteristics of riverside settlement using architectural image observation method, space syntax method for analyzing settlement configuration genotype, connectivity, interface and interlink territory integration, as well as questionnaire and interview methods to assess the perceptions of residents and municipal authorities. From the results of this research, five compositions forms have been identified: attachment to riverside settlement identity in the form of pilling, spanning, floating, embracing, and ascending with elements such as waterfront alleys, jukung (traditional boat), lanting (floating houses) as well as floating traditional markets that serves as the frame to the configuration. The identification process is done by using the approach of observing the spaceuse appropriation and the space-user perception on how to consider its sustainability aspect as a means to determine a level of adjustment. The result shows that self organized and self customized kampong residents and tourist are aware towards the river environment, the assets of local floating markets as well as the local social space. On the other hand, municipal authorities gave more attention to formal normative and regulative aspects. This analysis is used as the basis for recommendations for kampong riverside settlement design consolidation, which is done through guided participatory design workshops.

The result of this study is constructed as a concept for urban riverfront composition architecture, amphibious space territory, and urban riverfront settlement identity and expected to be able to further advance the knowledge surrounding the subject of urbanism and territoriality.
The Change of Space Use of Shared Space from Landed to High-Rise Settlement
Authors: Setyo Adiyanti Ayuko , Nareswari Ardhya , Rani Suryandono Alexander
Published: January 2018

Indonesia is entering an era of urban settlement transformation from horizontal landed living settlement to low-rise settlement, into the construction of vertical high-rise settlement. This resulted in the landed settlement residents that being moved to high-rise settlement, they have encountered a change of high-rise vertical living culture that different from their living culture before. This study aims to find out the use of shared space in landed living and high-rise settlement. The research method used in this research is qualitative descriptive study. The site of the research is in the landed settlement of Kampung Pulo and the high-rise settlement of Jatinegara Barat. Kampung Pulo settlement is a residence of Jatinegara Barat residents before they are moved. The result of the research shows the change of space use for shared space from landed to high-rise settlement; (1) landed settlement more accommodate the diversity of communal activities than high- rise settlement. (2) in the landed settlement there is a territory transition space that accommodates the needs of interaction, homebased business activities, and play, whereas high-rise settlement there is no more transition space, so the need for interaction and play is contained in the public space, while the trading activities needs are mostly found within the private area. (3) In landed settlements, the shared space used for communal activities is more multifunctional than high rise settlement.
The Relationship Between Spatial Configuration and Social Interaction in High-Rise Flats: A Case Study On The Jatinegara Barat in Jakarta.
Authors: Ridwana Rifan , Prayitno Budi , Utomo Hatmoko Adi
Published: January 2018

The construction of high-rise flats to minimize urban slum areas in Indonesia still create space use behavior problems for its residents due to the changes of space configuration between high-rise landed housing. Conventional high-rise flats cannot well accommodate the needs of social interactions happened in landed housing because of its spatial limitation that leads to uncertainty of space use behavior settings. This study aims to understand the relationship between spatial configuration on high-rise flats and social interaction levels of its residents. The object of study is Jatinegara Barat high-rise flats built to relocate slums community from the landed housing in Kampong Pulo. This study applies mix method research using space syntax method to analyze spatial configuration by looking at connectivity and space integration values, and then comparing it with social interaction data from place centered observation to find out the level of interaction and spaces tendency used interaction place.

The results of this study indicate that: (1) the relationship of spatial configuration to social interaction level in Jatinegara Barat flats can be positive or negative. (2) Positive relationships are found on the1st and 2ndfloor areas. High configuration values with high interaction levels are found in shared spaces on the 1st and 2nd floors with characteristics such as open space, large space, and availability of interaction supporting elements, while low configuration values with low interaction levels are found in more confined spaces such as private spaces and narrow corridors. (3) Negative relationships are found in the corridor and shared space in front of the elevator on each typical floors. Shared space in front of the elevator that has high spatial configuration value with large area show a low level of social interaction. While corridor with lower configuration value with the narrow area but have supporting elements such as chairs, mats, and shops have a higher level of social interaction. (4) This study shows that in the case of the relationship between spatial configuration and social interaction, availability of interaction supporting elements has greater influence rather than any other spatial factors.
Concise Synthesis of Macrocycles by Multicomponent Reactions
Authors: Dömling Alexander , Abdelraheem Eman , Khaksar Samad
Published: January 2018

A short reaction pathway was devised to synthesize a library of artificial 18–27-membered macrocycles. The five-step reaction sequence involves ring opening of a cyclic anhydride with a diamine, esterification, coupling with an amino acid isocyanide, saponification, and, finally, macro-ring closure using an Ugi or, alternatively, a Passerini multicomponent reaction. Three out of the five steps allow for the versatile introduction of linker elements, side chains, and substituents with aromatic, heteroaromatic, and aliphatic character. The versatile pathway is described for 15 different target macrocycles on a mmol scale. Artificial macrocycles have recently become of great interest due to their potential to bind to difficult post-genomic targets.
Rectal Atresia and Congenital Hypothyroidism: An Association or Coincidence?
Authors: Mehmetoğlu Feride
Published: January 2018

Rectal atresia is a rare anorectal malformation, and its association with other anomalies is even more rare. This study presents a unique case of co-twin in which the surviving newborn male underwent surgery due to rectal atresia. Newborn screening tests identified congenital hypothyroidism. The surgical treatment consisted of three stages and thyroid hormones were replaced.
Prevalence and Risk Factors of Acute Pulmonary Embolism in Patients with Lung Cancer Surgery
Authors: Li Yu-ping , Shen Lei , Huang Wei , Hu Xue-fei , Xie Dong , Yang Jian , Song Xiao , Zhao Yan-feng , Zhou Chao-jie , Jiang Ge-ning
Published: January 2018

Acute pulmonary embolism (PE) is one of the serious complications with high mortality after thoracic surgery. The authors aimed to determine the prevalence of PE events and evaluate additional risk factors for PE in patients with lung cancer surgery. Patients underwent lung cancer resections during January 2012 to July 2015 and had 30-day postoperative follow-up were included. Those with incomplete or miscoded data were excluded. The number of postoperative PE events was recorded retrospectively. Analyses were used to evaluate risk factors of PE during the hospitalization. The authors reviewed 11,474 patients who underwent surgery for lung cancer. The overall 30-day incidence of PE after thoracic surgery at their institution was 0.53%. The 30-day PE incidence without chemical prophylaxis was 0.57% (55/9,726) and the mortality rate was 10%. Multivariate analyses revealed that age over 66 (odds ratio [OR]: 1.09, 95% confidence interval [CI]: 1.05–1.12, p < 0.001), more extensive surgery than lobectomy (OR: 2.34, 95% CI: 1.28–4.25, p = 0.006) and stage IV of lung cancer (OR: 4.22, 95% CI: 1.50–11.9, p = 0.007) were associated with an increased risk of PE. Using these additional risk factors, based on readily available clinical characteristics, can help to risk-stratify patients and warrant extended chemical prophylaxis for patients to reduce the incidence of acute PE.
Laparoscopic Finding of Ectopic Adrenocortical Tissue in a 2-Year-Old Boy with Vanishing Testis
Authors: Marte Antonio
Published: January 2018

Ectopic adrenocortical tissue (EAT) along the spermatic cord is an unusual condition in children. The author reports on a 2-year-old boy with impalpable testis. On laparoscopy, EAT was detected along the hypotrophic spermatic vessels and excised. These remnants should be removed to prevent hormone production or malignant transformation.
Simulation als Fortbildungsmethode zur Professionalisierung von Teams
Authors: Flentje Markus , Eismann Hendrik , Sieg Lion , Friedrich Lars , Breuer Georg
Published: January 2018

Simulation ist eine Methode, virtuelle Lernumgebungen zu erzeugen. Mittels Simulation können Technical Skills, aber auch Soft Skills wie die Funktionsfähigkeit von Teams sehr gut vermittelt werden. Dieser Team-Aspekt wird nachfolgend vor dem Hintergrund spezifischer Trainingsmethoden näher beleuchtet. Der Artikel bezieht sich dabei auf „Zwischenfalltrainings“, die in den Zentren der Autoren einen großen Anteil des Kursangebotes einnehmen.
Neurologischer Schaden nach Wirbelsäulen-OP
Authors: Hachenberg Thomas , Kols Kerstin
Published: January 2018

Schlichtungsstellen für Arzthaftpflichtfragen bieten Patienten, Ärzten und Versicherern eine Möglichkeit, Arzthaftungsstreitigkeiten außergerichtlich zu klären. In der Rubrik „Fälle der Schlichtungsstelle“ stellen wir abgeschlossene Fälle aus der Schlichtungsstelle für Arzthaftpflichtfragen der norddeutschen Ärztekammern vor.
New Phenylethanoid Glycosides from Cistanche phelypaea and Their Activity as Inhibitors of Monoacylglycerol Lipase (MAGL)
Authors: Beladjila Khadidja , Berrehal Djemaa , De Tommasi Nunziatina , Granchi Carlotta , Bononi Giulia , Braca Alessandra , De Leo Marinella
Published: January 2018

Four new phenylethanoid glycosides (1–4), 1-β-p-hydroxyphenyl-ethyl-2-O-acetyl-3,6-di-α-l-rhamnopyranosyl-β-d-glucopyranoside (1), 1-β-p-hydroxyphenyl-ethyl-3,6-O-di-α-l-rhamnopyranosyl-β-d-glucopyranoside (2), 1-β-p-hydroxyphenyl-ethyl-2-O-acetyl-3,6-di-α-l-rhamnopyranosyl-4-p-coumaroyl-β-d-glucopyranoside (3), and 1-β-p-hydroxyphenyl-ethyl-3,6-di-α-l-rhamnopyranosyl-4-p-coumaroyl-β-d-glucopyranoside (4), together with three known compounds, were isolated from the n-butanol extract of Cistanche phelypaea aerial parts. The structural characterization of all compounds was performed by spectroscopic analyses, including 1D and 2D NMR, and HRESIMS experiments. The isolated compounds were assayed for their inhibitory activity on two enzymes involved in the peculiar glycolytic or lipidic metabolism of cancer cells, human lactate dehydrogenase (LDH), and monoacylglycerol lipase (MAGL), respectively. All the compounds showed negligible activity on LDH, whereas some of them displayed a certain inhibition activity on MAGL. In particular, compound 1 was the most active on MAGL, showing an IC50 value of 88.0 µM, and modeling studies rationalized the supposed binding mode of 1 in the MAGL active site.
A local sensor for joint temperature and velocity measurements in turbulent flows
Authors: Salort Julien , Rusaouën Éléonore , Robert Laurent , du Puits Ronald , Loesch Alice , Pirotte Olivier , Roche Philippe-E. , Castaing Bernard , Chillà Francesca
Published: January 2018

We present the principle for a micro-sensor aimed at measuring local correlations of turbulent velocity and temperature. The operating principle is versatile and can be adapted for various types of flow. It is based on a micro-machined cantilever, on the tip of which a platinum resistor is patterned. The deflection of the cantilever yields an estimate for the local velocity, and the impedance of the platinum yields an estimate for the local temperature. The velocity measurement is tested in two turbulent jets: one with air at room temperature which allows us to compare with well-known calibrated reference anemometers, and another one in the GReC jet at CERN with cryogenic gaseous helium which allows a much larger range of resolved turbulent scales. The recording of temperature fluctuations is tested in the Barrel of Ilmenau which provides a controlled turbulent thermal flow in air. Measurements in the wake of a heated or cooled cylinder demonstrate the capability of the sensor to display the cross correlation between temperature and velocity correctly.
Effects of cross-linking on partitioning of nanoparticles into a polymer brush: Coarse-grained simulations test simple approximate theories
Authors: Ozmaian Masoumeh , Jasnow David , Eskandari Nasrabad Afshin , Zilman Anton , Coalson Rob D.
Published: January 2018

The effect of cohesive contacts or, equivalently, dynamical cross-linking on the equilibrium morphology of a polymer brush infiltrated by nanoparticles that are attracted to the polymer strands is studied for plane-grafted brushes using coarse-grained molecular dynamics and approximate statistical mechanical models. In particular, the Alexander-de Gennes (AdG) and Strong Stretching Theory (SST) mean-field theory (MFT) models are considered. It is found that for values of the MFT cross-link strength interaction parameter beyond a certain threshold, both AdG and SST models predict that the polymer brush will be in a compact state of nearly uniform density packed next to the grafting surface over a wide range of solution phase nanoparticle concentrations. Coarse grained molecular dynamics simulations confirm this prediction, for both small nanoparticles (nanoparticle volume = monomer volume) and large nanoparticles (nanoparticle volume = 27 × monomer volume). Simulation results for these cross-linked systems are compared with analogous results for systems with no cross-linking. At the same solution phase nanoparticle concentration, strong cross-linking results in additional compression of the brush relative to the non-crosslinked analog and, at all but the lowest concentrations, to a lesser degree of infiltration by nanoparticles. For large nanoparticles, the monomer density profiles show clear oscillations moving outwards from the grafting surface, corresponding to a degree of layering of the absorbed nanoparticles in the brush as they pack against the grafting surface.
Relation between film thickness and surface doping of MoS2 based field effect transistors
Authors: Lockhart de la Rosa César J. , Arutchelvan Goutham , Leonhardt Alessandra , Huyghebaert Cedric , Radu Iuliana , Heyns Marc , De Gendt Stefan
Published: January 2018

Ultra-thin MoS2 film doping through surface functionalization with physically adsorbed species is of great interest due to its ability to dope the film without reduction in the carrier mobility. However, there is a need for understanding how the thickness of the MoS2 film is related to the induced surface doping for improved electrical performance. In this work, we report on the relation of MoS2 film thickness with the doping effect induced by the n-dopant adsorbate poly(vinyl-alcohol). Field effect transistors built using MoS2 films of different thicknesses were electrically characterized, and it was observed that the ION/OFF ratio after doping in thin films is more than four orders of magnitudes greater when compared with thick films. Additionally, a semi-classical model tuned with the experimental devices was used to understand the spatial distribution of charge in the channel and explain the observed behavior. From the simulation results, it was revealed that the two-dimensional carrier density induced by the adsorbate is distributed rather uniformly along the complete channel for thin films (<5.2 nm) contrary to what happens for thicker films.
Angle- and polarization-insensitive broadband metamaterial absorber using resistive fan-shaped resonators
Authors: Nguyen Toan Trung , Lim Sungjoon
Published: January 2018

In this paper, we propose an angle- and polarization-insensitive broadband metamaterial absorber with a resistive fan-shaped resonator. First, the symmetric fan-shaped resonator is designed, and four lumped resistors are loaded in the gap between each fan-shaped circular sector on the top layer to increase the bandwidth. Based on the circuit parameters, the periodic structure of the fan-shaped resonator is designed using full-wave analysis. The proposed absorber is fabricated using a printed circuit board process in a single layer. The experimental results indicate that an absorptivity value greater than 96% was achieved in the frequency range of 7–12.8 GHz for all polarization angles at normal incidence. Under oblique incidence, the measured absorptivity was greater than 90% in the range of 7–12.1 GHz when the incident angle varied from 0° to 45° in the transverse electric mode. In the transverse magnetic mode, the measured absorptivity was greater than 90% between 7.1 and 9.3 GHz when the incident angle varied from 0° to 45°.
Acoustic bubble dynamics in a microvessel surrounded by elastic material
Authors: Wang S. P. , Wang Q. X. , Leppinen D. M. , Zhang A. M. , Liu Y. L.
Published: January 2018

This paper is concerned with microbubble dynamics in a blood vessel surrounded by elastic tissue subject to ultrasound, which are associated with important applications in medical ultrasonics. Both the blood flow inside the vessel and the tissue flow external to the vessel are modeled using the potential flow theory coupled with the boundary element method. The elasticity of tissue is modeled through the inclusion of a pressure term in the dynamic boundary condition at the interface between the two fluids. Weakly viscous effects are considered using viscous potential flow theory. The numerical model is validated by comparison with the theoretical results of the Rayleigh-Plesset equation for spherical bubbles, the numerical results for acoustic bubbles in an unbounded flow, and the experimental images for a spark generated bubble in a rigid circular cylinder. Numerical analyses are then performed for the bubble oscillation, jet formation and penetration through the bubble, and the deformation of the vessel wall in terms of the ultrasound amplitude and the vessel radius.
Zwitterionization of glycine in water environment: Stabilization mechanism and NMR spectral signatures
Authors: Valverde Danillo , da Costa Ludwig Zélia Maria , da Costa Célia Regina , Ludwig Valdemir , Georg Herbert C.
Published: January 2018

At physiological conditions, myriads of biomolecules (e.g., amino acids, peptides, and proteins) exist predominantly in the zwitterionic structural form and their biological functions will result in these conditions. However these geometrical structures are inaccessible energetically in the gas phase, and at this point, stabilization of amino-acids in physiological conditions is still under debate. In this paper, the electronic properties of a glycine molecule in the liquid environment were studied by performing a relaxation of the glycine geometry in liquid water using the free energy gradient method combined with a sequential quantum mechanics/molecular mechanics approach. A series of Monte Carlo Metropolis simulations of the glycine molecule embedded in liquid water, followed by only a quantum mechanical calculation in each of them were carried out. Both the local and global liquid environments were emphasized to obtain nuclear magnetic resonance (NMR) parameters for the glycine molecule in liquid water. The results of the equilibrium structure in solution and the systematic study of the hydrogen bonds were used to discard the direct proton transfer from the carboxyl group to the ammonium group of the glycine molecule in water solution. The calculations of the Density Functional Theory (DFT) were performed to study the polarization of the solvent in the parameters of nuclear magnetic resonance of the glycine molecule in liquid water. DFT calculations predicted isotropic chemical changes on the H, C, N, and O atoms of glycine in liquid water solution which agree with the available experimental data.