bluuebunny/crossref_metadata_2025 huggingface dataset:
The Optimization Of Flash Sale Voucher For Promotion At Vila Lumbung Hotel, Seminyak-Bali
Authors: Satya Wiguna I Komang Esa Wira , Lukitasari Rimalinda , Pramesti Dinar Sukma
Published: June 2024

Voucher Flash Sale is a form of marketing strategy carried out by Hotel Vila Lumbung. Unfortunately, the use of Flash Sale vouchers has not been effective because the sales results have not been able to reach the target. The purpose of this study was to develop a promotional strategy through the use of flash sale vouchers at Hotel Vila Lumbung, Seminyak-Badung. The research method used is qualitative by collecting data through interviews, using marketing mix theory and using SWOT analysis techniques. The results of the study reveal strategies that can be carried out including promoting Flash Sale Vouchers at other OTAs such as fave, traveloka, hotelbeds, roiback and others who have collaborated with the hotel; provide free charge rewards for one day using hotel facilities for each internal staff who successfully sells Flash Sale Vouchers; provide a special barcode in the Flash Sale Voucher which can be accessed online or offline; utilizing hotel facilities as a form of benefit to those who promote it, so that this can minimize the use of budget in the promotion process of Flash Sale Vouchers. With this research, it is hoped that Hotel Vila Lumbung Seminyak-Badung can maximize its strategy in promoting Flash Sale Vouchers.
Development Of The Ogoh-Ogoh Parade From A Religious Ritual To A Tourist Attraction In Bali
Authors: Prianta Putu Agung , Sulistyawati Anastasia
Published: June 2024

The Ogoh-ogoh parade has become one of the events in the Hindu religious rituals to welcome Nyepi Day. Its initial development from a cultural element transformed into a religious ritual and further commodified into a tourist attraction. The research aims to explore the historical development of the Ogoh-ogoh parade in the context of religion and tourism and to understand the impact of the Ogoh-ogoh parade's transformation on the cultural identity and religious practices of the Balinese community. The theories employed include cultural transformation, cultural commodification, and cultural change. A qualitative method with data collection through literature study was used. The research findings reveal various histories of Ogoh-ogoh: the pitra yadnya (Sang Kalika), the Barong Landung, the boredom of statue craftsmen, the Ngusaba Ndong-Nding, and the adaptation of scarecrow. It became a tourist object because Ogoh-ogoh is not mentioned in Hindu scriptures or sacred texts. The impacts of the parade as a tourist attraction include changes in interpersonal community relationships, an increase in anomalies, cultural identity and religious rituals, and an increase in tourist visits. This study is expected to provide new insights into how the religious community and the Balinese society in general respond to the pressures of modernization and globalization.
Modification Of Base Genep Instant Bali Seasoning Using Fdh6 Type Dehydrator
Authors: Pramudia Heru , Tanius Billy
Published: June 2024

This research concerns the findings of the formulation of the balinese seasoning base genep dry instant, related to the formulation of spices for balinese specialties which so far are in pasta packaging or are generally known as the seasoning wet base genep. Through food technology applications, this spice is dried using a dehydrator machine. This dry seasoning is expected to be easier and more efficient to use in various balinese dishes, and durable in storage. The methodology of this research is experimental, with steps to standardize the appropriate seasoning recipe, dry the seasoning with a dehydrator, and apply the dry seasoning for using in chicken betutu. Then do a preference level assessment test by expert panelists. The expert panelists used in this study were members of the Indonesian Chef Association Bali (ICA Bali). All panelists work as cooks or chefs and are native balinese who are accustomed to enjoying betutu chicken for generations. The results of the research on the level of preference for this instant seasoning are on average at a score of 4. This means that the panelists like the taste, aroma, texture, and color of using base genep seasoning. As we know in using of instant seasoning, being increasingly popular in the catering, hotel, and restaurant industries. This provides an opportunity to produce base genep instant seasoning on an industrial scale.
The Influence Of Generation Z Participation In Implementing Events In Tabanan District Tourism Villages
Authors: Sri Candrawati Anak Agung Ketut , Prianta Putu Agung , Wahyuni A. A. Nyoman Sri
Published: June 2024

Tabanan Regency has 133 villages, 28 of which have become tourist villages in 2023. Several tourist villages hold promotional events through social media. Generation Z uses social media the most, but tourist village managers have not involved Generation Z much, including in organizing events. The purpose of this study was to analyze the participation and influence of generation Z in implementing events in Tabanan Regency Tourist Villages. Mixed research methods. Primary and secondary data collection techniques were carried out by means of observation, interviews, questionnaires, literature studies and document studies. The analysis technique used the Statistical Test t (t-test). This research theory, the theory of participation, classifies participation into 2 based on its involvement, namely direct participation and indirect participation. In conclusion, that the participation of generation Z (aged 11-26 years) in organizing events in Tabanan Regency Tourist Villages is still not optimal, namely 12.4%, while the results of the T test concluded that Gen Z partially has a significant influence on organizing events in Tabanan Regency tourist villages.
SILÊNCIO E DIREITO INTERNACIONAL DOS DIREITOS HUMANOS
Authors: Ferreira Natália Damazio Pinto , Mello Nina Castro Adeodato Barrouin e
Published: June 2024

Este artigo visa analisar, a partir de contribuições teórico-políticas decoloniais, o litígio estratégico no Sistema Interamericano de Direitos Humanos, considerando a centralidade das dimensões de gênero e raça. A investigação se orienta a partir da análise de casos e medidas de urgência que estão ou estiveram em trâmite contra o Brasil entre 1989-2018, a respeito de sistema prisional ou espaços que tenham sido utilizados com a mesma finalidade, como delegacias de polícia. Será observado se as estratégias, demandas e narrativas presentes nos documentos analisados, tanto de casos individuais, quanto coletivos, vêm gestando decisões que podem, ou não, oferecer       um instrumental que auxilie as lutas para o combate a opressões estruturais. Ou se têm operado enquanto uma medida de reforço colonial quando versa sobre mulheres presas que são, em sua maioria, negras.
Do ônibus ao elevador: o crime de importunação sexual e a salvaguarda do bem jurídico da dignidade e da liberdade sexual para as mulheres
Authors: Rolim Ana Paula França , Pontes Francisca Amélia de Souza , Carvalho João Mikael Costa de
Published: June 2024

A pesquisa tem como objeto o estudo do crime de importunação sexual, com breves apontamentos acerca de seu histórico, de sua classificação e de seu posicionamento como importante peça subsidiária do aparato repressor penal referente aos crimes contra a dignidade sexual e, mais especificamente, contra a liberdade sexual, com foco na análise de situações hipotéticas deduzidas a partir de um caso ainda em investigação de suposta importunação sexual ocorrida em um elevador em Fortaleza. O acusado está amparado pelo princípio da presunção de inocência, logo, em momento algum far-se-á qualquer sugestão de incriminação do acusado em si, mas sim serão apuradas as condutas em um contexto de abstração, para verificar se situações do dia a dia implicadas nas acusações apresentadas podem ser enquadradas como pertencentes ao fato típico do crime de importunação sexual. Ademais, serão desenvolvidos corolários históricos e pautados em estudos de gênero que demonstram a paulatina opressão sofrida pelas mulheres na sociedade brasileira, sendo o crime de importunação sexual um importante sustentáculo para a defesa desse grupo específico de pessoas no seio social brasileiro.
A possibilidade de decretação de divórcio como medida liminar em casos de violência doméstica e os posicionamentos doutrinários e jurisprudenciais no Brasil
Authors: Oliveira Beatriz Fagionato , Buzolin Laura Guimarães
Published: June 2024

O presente trabalho tem como objetivo compreender as relações familiares, sobretudo no âmbito das relações de gênero, bem como os direitos garantidos às mulheres nesse contexto. Igualmente, intenta o estudo da efetiva concretização deles, considerada a vulnerabilidade feminina decorrente da realidade machista e patriarcal que permeia a grande maioria das esferas da sociedade. Nesse sentido, pretende-se, por meio da análise legislativa, examinar a possibilidade de decretação de divórcio preliminarmente, após requerimento liminar, nos casos de violência doméstica e, inclusive, de existência de medida protetiva em favor de cônjuge. Ademais, considerando todo o cenário exposto, serão explorados os posicionamentos doutrinário e jurisprudencial no que tange ao assunto, os quais possuem tendências favoráveis e desfavoráveis sobre o tema.
The freedom of religion of children
Authors: Schanda Balázs
Published: June 2024

The Convention on the Rights of the Child recognises the right of the child to freedom of thought, conscience and religion. In the wording of the Convention, parents provide direction in exercising this right. Other human rights instruments lay more emphasis on parental rights. It is the natural right of parents to strive to pass on their own convictions and traditions to their children. There are good reasons for the neutral state to keep out from religious disputes as well as from the religious life of families. State involvement should be reserved for extreme cases, but it may be inevitable when family relations break down. Prudence is needed to promote peace in the family and society instead of raising internal and religious tensions.
ANALISIS STRATEGI PEMASARAN SYARIAH UNTUK PENINGKATAN PENJUALAN OLAHAN SINGKONG DALAM MENGHADAPI PERSAINGAN USAHA PADA PELAKU UMKM DIDESA SUMBER GENTONG JATIGUNTING WONOREJO PASURUAN
Authors: Hamimah
Published: June 2024

Strategi pemasaran merupakan suatu rencana terpadu yang menyeluruh dibidang pemasaran dalam rangka mencapai tujuan perusahaan. Sedangkan persaingan bisnis adalah pertandingan, kompetisi atau kegiatan bersaing.Dalam era globalisasi, dimana tingkat persaingan bisnis yang sangat tajam, maka setiap perusahaan harus memperhatikan salah satu aspek yang sangat vital dalam manajemen perusahaan yaitu bidang pemasaran. Rumusan masalah pada penulisan ini yang pertama adalah Bagaimana sistem penjualan olahan singkong masyarakat dusun Sumber Gentong Wonorejo Pasuruan? Yang kedua Bagaimana strategi pemasaran syariah olahan singkong dalam menghadapi persaingan didesa Sumber Gentong? Tujuan penelitian ini adalah Untuk menganalasis strategi pemasaran syariah olahan singkong masayarakat dusun sumber gentong, wonorejo pasuruan. Sumber data yang digunakan dalam penelitian ini adalah data primer dan sekunder yaitu berupa wawancara, observasi dan dokumentasi dengan pihak-pihak terkait. Metode yang digunakan adalah metode analsis deksriptif. Penelitian ini meghasilkan strategi pemasaran UMKM olahan singkong dalam menghadapi persaingan masih sangat sederhana. Dan untuk pemberlakuan konsep strategi pemasaran masih memakai price dan product, sedangkan untuk place dan promotion masih jarang digunakan.
 
Kata Kunci : Strategi pemasaran syariah, pasar, persaingan
DAFTAR PUSTAKA
Algrina Agnes Ulus, “Bauran Pemasran Pengaruhnya Terhadap Keputusan Pemeblian Mobil Daihatsu pada PT. Astra Internasional Manado”, ( Manado: Jurnal Emba: Jurnal Riset Ekonomi, Manajemen, Bisinis dan Akuntansi, 2013), 4
Arlina Nurbaity Lubis, “Strategi Pemasaran dalam Persaingan Bisnis”, (Sumatera Utara: Universitas Sumatera Utara, 2004), 1
Citra Pratama,(Peran Zakat dalam Penenggulangan Kemiskinan), Tauhidinomics: Jurnal of Islamic Banking and Economics, 2015, 93-104.
Fazli Rahman, dkk, (Pelaksanaan Kurikulum PPKN Pada Kondisi Khusus Pandemic Covid-19), Jurnal Basicedu, 2021,5682-5691
Indri Yovita Toti indrawati, “Analisis Sumber Modal Pedagang Pasar Tradisional Dikota Pekanbaru,” jurnal ekonomi (2014): 1–8.
Mudjia Raharjo, (Metode Pengupulan DataPenelitian Kalitatif).

Eko Prasetyo, Peran Usaha Mikro Kecil dan Menengah(UMKM) dalam Kebijakan Penanggulangan Kemiskinan dan Pengangguran, ( Akademika, 2008), p1-13

Purnama Putra, Wiwik Hasbiyah, Teori dan Praktik Pemasaran Syariah, (Depok: Rajawali Press, 2018).
Ustadus Sholihin,”Analisis Strategi Pemasaran dalam Menghadapi Persaingan Usaha pada Perusahaan Kain dan Tenun ikat cap Sinar Barokah Kediri”, (Kediri: Jurnal Cendikia, 2014), 5.
FAKTOR-FAKTOR YANG MEMPENGARUHI MINAT MAHASISWA EKONOMI SYARIAH FAKULTAS EKONOMI DAN BISNIS (FEB) MENJADI CALON NASABAH BANK SYARIAH INDONESIA
Authors: Rafy Muhammad Toha  , Ghaitsa Zahira Ardelia Putri  , Muhammad Faisal  , Abiyyu Akbar Aristy
Published: June 2024

Penelitian ini berupaya untuk mengidentifikasi dan menjelaskan elemen-elemen yang mempengaruhi kecenderungan mahasiswa ekonomi syariah FEB UIN Jakarta untuk menjadi patron Bank Syariah Indonesia. Partisipan yang dilibatkan dalam penelitian ini adalah 30 mahasiswa peminatan ekonomi syariah dari FEB UIN Jakarta. Kuesioner dibagikan untuk mengumpulkan sampel. Analisis data dilakukan dengan menggunakan metode statistik dengan menggunakan perangkat lunak SPSS versi 25. Analisis data menggunakan uji t menunjukkan adanya pengaruh yang besar dan positif antara faktor pelayanan dan pengetahuan terhadap minat mahasiswa ekonomi syariah di FEB UIN Jakarta. Variabel promosi, lokasi, sistem keamanan, variasi produk, reputasi, dan kepatuhan terhadap prinsip ekonomi syariah tidak berpengaruh signifikan terhadap minat mahasiswa ekonomi syariah FEB UIN Jakarta. Gabungan pengaruh pelayanan, promosi, lokasi, keahlian, sistem keamanan, keragaman produk, reputasi, dan ketaatan terhadap prinsip ekonomi syariah sangat mempengaruhi keinginan mahasiswa ekonomi syariah FEB UIN Jakarta untuk menjadi nasabah Bank Syariah Indonesia
 
Kata Kunci : BSI, Mahasiswa Eksyar, Minat, Pelayanan, Pengetahuan
Wawasan tentang Reaksi Generasi Milenial terhadap Konten Pacar Pribadi @cerminlelaki
Authors: Aprillia Titania , Hariyanto Didik
Published: June 2024

Studi ini menyelidiki penerimaan kerentanan pria yang ditampilkan dalam konten foto akun Instagram @cerminlelaki oleh para pengikut perempuan milenial, dengan menggunakan analisis penerimaan Stuart Hall. Dengan memanfaatkan wawancara kualitatif mendalam dengan lima informan perempuan milenial, penelitian ini mengungkapkan interpretasi dan tingkat penerimaan yang bervariasi di antara peserta, yang menyoroti negosiasi yang dipengaruhi oleh latar belakang sosial, budaya, pengalaman, dan lingkungan yang beragam. Temuan tersebut menekankan penerimaan yang halus terhadap kerentanan pria dalam ruang digital dan implikasinya untuk memahami dinamika gender kontemporer dan strategi komunikasi.
Implementasi Program Bantuan Pangan Non Tunai dalam Komunikasi dan Perubahan Sosial Pembangunan Ekonomi
Authors: Meidiana Aaliyah , Helmi Canisa
Published: June 2024

Tujuan dari program Bantuan Pangan Non Tunai (BPNT) yang dicanangkan pemerintah Indonesia adalah memberikan bantuan pangan secara langsung kepada keluarga miskin dan membutuhkan dengan menggunakan kartu elektronik. Penerima manfaat BPNT menerima saldo elektronik yang dapat dipergunakan untuk membeli berbagai jenis bahan pangan di toko yang telah bekerja sama dengan program, seperti pasar tradisional atau toko kelontong. Program BPNT bertujuan untuk meningkatkan aksesibilitas dan ketersediaan makanan bagi keluarga miskin dan rentan serta memastikan bahwa bantuan yang diberikan tepat sasaran. Dengan menggunakan kartu elektronik, program ini juga bertujuan untuk meningkatkan efektivitas distribusi makanan, mengurangi kemungkinan penyalahgunaan, dan memperluas jangkauan program bantuan sosial. Dalam upaya pemerintah Indonesia untuk mengatasi kelaparan, program BPNT telah menjadi salah satu alat penting.
Unravelling Catch-Up Fridays: A Look through Novice Teachers’ Perspectives
Authors:   Cabuloan Elementary School, Cabuloan, Sta. Catalina, Ilocos Sur, Philippines, Rafanan Rizalino R. , Pimienta Dhean Jencel O. ,   Binalayangan Elementary School, Quimmarayan, Sto. Domingo, Ilocos Sur, Philippines, Cacatian Sheryl P. ,   Narvacan North Central School, Turod, Narvacan, Ilocos Sur, Philippines, Soria Mirriam P. ,   Narvacan North Central School, Turod, Narvacan, Ilocos Sur, Philippines
Published: June 2024

Given the critical role of reading proficiency in learner success, the Department of Education’s (DepEd) Catch-Up Fridays program holds promise for improving literacy skills. Prioritizing this program at the school level is essential. However, a potential challenge lies in ensuring the preparedness of novice teachers, those new to the profession, to implement such initiatives effectively. This study aimed to understand the experiences of novice teachers in the first month of implementation of Catch-Up Fridays in the 1st District of Ilocos Sur. The participants of the study were five (5) teachers. They were selected based on the inclusion criteria: 1) 0-3 years in the service, 2) a DepEd employee, 3) a resident of Unit II (Bantay, Caoayan, Santa, San Vicente, Sta. Catalina, Sto. Domingo, and San Ildefonso), and 4) must be willing to participate in the study. This study utilized phenomenological research, applying the focus group discussion and semi-structured open-ended questions. Data collection involved verbatim transcription of participant responses. These transcripts were then systematically analyzed using the Moustakas framework. This analysis included listing, categorization, coding, and thematic identification. The findings indicated that novice teachers viewed their experiences of the first month of Catch-Up Fridays as a Symphony of Emotions-Frustrations to Aspirations with two sub-themes emerging, namely having mixed emotions and being optimistic in enhancing literacy skills. All the novice teacher participants went through a stressful, struggling, and confused phase caused by inadequate resources and lack of training. Amidst the challenges they faced during the first month of implementation of Catch-Up Fridays, they were optimistic for a better outcome because there was an improvement in learners’ literacy. Even though novice teachers typically display commendable optimism amid hard times, focused assistance can boost the effective execution of the program. To enhance the effectiveness of school-level Catch-up Fridays, administrators could provide these educators with comprehensive orientation sessions or seminar workshops. However, making available teaching aids will help to reduce anticipated stress, thereby guaranteeing smooth program implementation.
Legal Protection for Deposit Customers Who Are Not Recorded after BPR’s Business License Is Revoked
Authors:   Warmadewa University & Terompong No.24, Sumerta Kelod, Denpasar, Bali 80239, Wenten Kadek , Kosasih Johannes Ibrahim ,   Warmadewa University & Terompong No.24, Sumerta Kelod, Denpasar, Bali 80239, Arjaya I Made ,   Warmadewa University & Terompong No.24, Sumerta Kelod, Denpasar, Bali 80239
Published: June 2024

Third-party fund collectors by Rural Banks (BPR) using a pick-up service system bear the risk of internal bank misconduct leading to the omission of customer deposits in the BPR's records. The research method employed is normative research aimed at understanding the prudence principle in fund collection and legal protection for depositors. The research benefits society by enhancing their understanding of their rights as depositors in BPR. The discussion results indicate that customer identification principles Know Your Customer (KYC) embody the prudence principle in fund collection. The Financial Services Authority (OJK) mandates that BPR be accountable for customers harmed by internal misconduct. However, after liquidation, the Deposit Insurance Corporation (LPS) does not guarantee these affected customers. In conclusion, there is a legal vacuum in protecting depositors post-BPR liquidation. The lack of legal certainty in fund collection through pick-up service leads to compensatory relationships between customers and bank staff. Recommendations include amending LPS regulations to provide legal protection for affected bank customers and enhancing supervision in third-party fund collection.
Islamic Practices and Muslim Students’ Academic Performance
Authors:   Department of Education, Misamis Oriental, Philippines, Southern de Oro Philippines College, Cagayan de Oro City, Philippines, Datuimam Jehan A. , Tantiado Rosalinda C. ,   Department of Education, Misamis Oriental, Philippines, Southern de Oro Philippines College, Cagayan de Oro City, Philippines
Published: June 2024

Islam practices are followed by Muslims as religious customs and events to observe affiliation with Islam. The purpose of these practices was meant to boost bond with Allah Subhanahu Wa Ta'ala (SWT) and encourage spiritual development. This study aimed to investigate the relationship between Muslim students' perceptions on Islam practices and their academic performance. The study employed a descriptive-correlational research design with content analysis using a researcher-made questionnaire which was reliability and validity tested. Descriptive statistics such as Mean, Standard Deviation and Pearson Product Moment Correlation Coefficient were utilized to analyze the data collected. Respondents were selected through stratified random sampling using Slovin’s Formula. Results showed that Muslim students abide Islamic Practices like Ramadan, Salah(prayer), and Jumaat (Friday prayer). Muslim students who pray five times a day tend to have a deep sense of gratitude and humility towards Allah. They have very satisfactory grades. Students’ Islamic practices and academic performance have significant correlation. Thus, this study suggests that schools may support the Muslim students in their practices by providing a modified environment in their learning process because the more they are abiding with Islamic practices, the more they strive to become better in their academic performance.
Sleep architecture of patients in the early recovery period after ischemic or hemorrhagic stroke
Authors:   Volgograd State Medical University, Kurushina Olga V. , Kurakova Elena A. ,   Volgograd State Medical University
Published: June 2024

Aim – to identify the differences in sleep architecture of patients in the early recovery period after ischemic and hemorrhagic stroke. Methods. The study involved 143 patients in their early post-stroke recovery period, the patients’ average age was 59.6 ± 7.4 years. Among subjects there were 69 males (48.2%) and 74 females (51.8%). A total of 62% (89 patients) had ischemic lesions, 38% (54 patients) had hemorrhagic lesions. Patients with insomnia were identified based on the results of preliminary questionnaire survey involving the use of the screening assessment scale of subjective sleep characteristics. Objective assessment of the night sleep architecture features was performed by polysomnography. Results. Comparative assessment of sleep architecture showed that the majority of surveyed patients had a combination of phenomenological sleep disorder types, however, predominance of presomnic disorders was reported in patients after ischemic stroke, while patients after hemorrhagic stroke showed predominance of intrasomnic disorders. The sleep stage duration alterations (larger share of superficial sleep and smaller share of deep sleep) were typical for both types of cerebrovascular disease, they were slightly more prominent in patients after ischemic stroke, which could be due to the brain tissue necrosis, cystic-gliotic changes in the affected area. Conclusions. The differences in sleep architecture identified are consistent with the papers by domestic and foreign researchers on the impaired structure and lower effectiveness of sleep in post-stroke patients. To date, the cause of significant alterations of sleep architecture in patients after ischemic stroke is poorly understood and requires further research in this area.
Traumatic brain injury: classification, clinical features, neuroimaging
Authors:   Burdenko National Medical Research Center for Neurosurgery, Likhterman Leonid В. , Kravchuk Alexander D. ,   Burdenko National Medical Research Center for Neurosurgery, Okhlopkov Vladimir A. ,   Burdenko National Medical Research Center for Neurosurgery
Published: June 2024

Modern classification of traumatic brain injury with identification of clinical and morphological variants is provided. Neurological semiotics and neuroimaging diagnosis of concussion, mild, moderate and severe cerebral contusion, compression of the brain with epidural, subdural and intracerebral hematomas are described based on the analysis of observations of the National Medical Research Center for Neurosurgery named after Academician N.N. Burdenko.
Advanced technology in glycemic control and prevention of diabetes mellitus complications
Authors:   Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia, Biryukova Elena V. ,   Loginov Moscow Clinical Scientific and Practical Center
Published: June 2024

The review is focused on the issues of blood glucose self-monitoring for prevention of the diabetes mellitus complications. The data of clinical trials and actual clinical practice are provided that demonstrate improved quality of life and carbohydrate metabolism indicators in patients using advanced technology.
A clinical case. Tuberculous lymphadenitis in a 10-year-old girl: what should not be forgotten
Authors:   Sechenov First Moscow State Medical University (Sechenov University), Aminova Alfiya I. , Feldfiks Larisa I. ,   Speransky Children City Clinical Hospital №9, Ibatullina Aliya I. ,   Sechenov First Moscow State Medical University (Sechenov University), Eryushova Tatiana Yu. , Muradova Nigar N. ,   Sechenov First Moscow State Medical University (Sechenov University), Kondrashova Anna D. ,   Sechenov First Moscow State Medical University (Sechenov University), Shcherbanyuk Ilona A. ,   Sechenov First Moscow State Medical University (Sechenov University), Khalilova Aysun A. ,   Sechenov First Moscow State Medical University (Sechenov University), Chukanova Anna V. ,   Sechenov First Moscow State Medical University (Sechenov University)
Published: June 2024

Tuberculosis is an infectious disease, with many forms and localizations, caused by Mycobacterium tuberculosis, which can affect any organs and tissues of the body. The paper presents a clinical case of tuberculosis of multiple locations, with the presence of resistance of M. tuberculosis to anti-tuberculosis drugs (moxifloxacin, amikacin, bedaquiline), manifesting with sluggish lymphadenopathy of the submandibular lymph nodes in a child who arrived in russia from Pakistan.
Case study: surgical treatment of patient with breast cancer
Authors:   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Lun'kova Mariya N. , Litvyakova Elena V. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ivanov S.A. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center,   National Medical Research Radiological Center, Kaprin A.D. ,   National Medical Research Radiological Center,   Patrice Lumumba People’s Friendship University of Russia,   Herzen Moscow Research Oncological Institute – branch of the National Medical Research Radiological Center, Denisov Maksim S. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Kiseleva Marina V. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center
Published: June 2024

Rare breast neoplasms are found by physicians in clinical practice. Phyllodes tumor of the breast accounting for 0.3–1% of all breast neoplasms is one of these neoplasms. Today, the phyllodes tumor etiology is unclear, the same as its pathogenesis. The paper reports an example of successful surgical treatment of malignant phyllodes tumor.
Intrauterine adhesions: old problem, new vision
Authors:   Patrice Lumumba Peoples' Friendship University of Russia,, Orazov Mekan R. , Mikhaleva Lyudmila M. ,   Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery, Ismailzade Sevindzh Ia. ,   Patrice Lumumba Peoples' Friendship University of Russia,, Soiunov Mukhammednazar A. ,   Patrice Lumumba Peoples' Friendship University of Russia,
Published: June 2024

In recent years, more and more attention has been paid in the scientific literature to the prediction and prevention of diseases affecting the quality and duration of life. Intrauterine synechiae is a multifactorial polygenic disease that remains with a low effectiveness of overcoming both forma-tion and treatment. With a reasonable systematic approach to the introduction of new methods of treatment and prevention, it will increase the effectiveness of solving this problem. Preservation of reproductive function and health is one of the most important problems of doctors of various specialties. This review presents modern paradigms of pathogenesis and treatment of intrauterine synechiae.
The minimally invasive method for treatment of stress urinary incontinence in women
Authors:   Moscow Regional Research Institute of Obstetrics and Gynecology, Balan Vera E. , Tikhomirova Elena V. ,   Moscow Regional Research Institute of Obstetrics and Gynecology, Chechneva Marina A. ,   Moscow Regional Research Institute of Obstetrics and Gynecology, Kapitanova Olga V. ,   Moscow Regional Research Institute of Obstetrics and Gynecology, Orlova Svetlana A. ,   Moscow Regional Research Institute of Obstetrics and Gynecology, Zhuravel Anastasiya S. ,   Moscow Regional Research Institute of Obstetrics and Gynecology, Kruchinina Elena V. ,   Moscow Regional Research Institute of Obstetrics and Gynecology, Petrukhin Vasilii A. ,   Moscow Regional Research Institute of Obstetrics and Gynecology
Published: June 2024

Urinary incontinence is a complex medical and social problem. Surgical methods designed to treat stress urinary incontinence are expensive and have a number of complications, and existing alternative surgical methods have been ineffective and caused complications due to the very nature of the fillers used. Today, a gel based on hyaluronic acid, DELIGHT® G®, has appeared on the pharmaceutical market, which is injected into the paraurethral area for the purpose of co-opting the urethra. Aim. To develop indications for paraurethral administration of DELIGHT® G® hyaluronic acid-based gel for stress urinary incontinence and to evaluate its effectiveness and safety. Materials and methods. The study involved 35 patients aged 45–55 with mild stress incontinence. Results. The effectiveness of urinary incontinence therapy was 97.1% (n=34). All patients underwent functional tests, uroflowmetry, profilome-try and ultrasound examination of the paraurethral area before and after paraurethral injection of hyaluronic acid-based gel. Uroflowmetry data: before the introduction of the gel, the average value of Qmax 27±1.5 ml/sec and Q average 13.5±2.7 ml/sec, immediately after the paraurethral in-jection of the gel, Qmax 19±2.1 ml/sec and Q average 12.6±1.6 ml/sec and after month Qmax 20±2.3 ml/sec and Q average 11.9±1.9 ml/sec. Profilom-etry data: the average length and functional length of the urethra were 34±0.9 mm and 31±0.8 mm, respectively, which indicates that this study is not informative. According to ultrasound examination of the paraurethral area, after the introduction of a gel based on hyaluronic acid into the paraurethral area, signs of urethral hypermobility and sphincter insufficiency are leveled. Conclusions. Paraurethral injection of hyaluronic acid-based gel can be considered as first-line therapy stress urinary incontinence for patients with initial manifestations of stress urinary incontinence.
argeted lymphadenectomy for breast cancer. Execution method. Clinical case
Authors:   Herzen Moscow Research Oncology Institute – branch of the National Medical Research Center of Radiology, Abdulloeva Shakhnoza Sh. , Kaprin Andrey D. ,   Herzen Moscow Research Oncology Institute – branch of the National Medical Research Center of Radiology,   National Medical Research Center of Radiology, Zikiryakhodzhaev Aziz D. ,   Herzen Moscow Research Oncology Institute – branch of the National Medical Research Center of Radiology,   Sechenov First Moscow State Medical University (Sechenov University), Prokopenko Sergey P. ,   Herzen Moscow Research Oncology Institute – branch of the National Medical Research Center of Radiology,   Patrice Lumumba Peoples' Friendship University of Russia, Saribekyan Eric K. ,   Herzen Moscow Research Oncology Institute – branch of the National Medical Research Center of Radiology, Rasskazova Elena A. ,   Herzen Moscow Research Oncology Institute – branch of the National Medical Research Center of Radiology, Mazo Mikhail L. ,   Herzen Moscow Research Oncology Institute – branch of the National Medical Research Center of Radiology,   Patrice Lumumba Peoples' Friendship University of Russia, Zanozina Ekaterina A. ,   Herzen Moscow Research Oncology Institute – branch of the National Medical Research Center of Radiology
Published: June 2024

There is a steady trend towards de-escalation of surgical intervention in the breast cancer treatment strategy. At first, this topic concerned the de-velopment and implementation of methods of organ-preserving operations on the mammary gland itself. With the advent of the concept and the development of the sentinel lymph node biopsy technique, the problem of performing a gentle lymphadenectomy with the prevalence of the cN0 process was solved. In recent years, the most innovative technique has begun to develop, namely targeted lymphadenectomy, which allows per- forming economical interventions on the lymph pathways with the prevalence of the cN1→ypN0 process, that is, in the presence of a verified metastatic lymph node with complete clinical resorption of metastasis during neoadjuvant polychemotherapy. The article is devoted to the de- scription of the technique of performing targeted lymphadenectomy.
Acute kidney injury in polymorbid patients
Authors:   Sechenov First Moscow State Medical University (Sechenov University), Lebedeva Marina V. , Kamyshova Elena S. ,   Sechenov First Moscow State Medical University (Sechenov University), Taranova Marina V. ,   Sechenov First Moscow State Medical University (Sechenov University), Beketov Vladimir D. ,   Sechenov First Moscow State Medical University (Sechenov University), Andreeva Elena Yu. ,   Sechenov First Moscow State Medical University (Sechenov University)
Published: June 2024

The presented clinical observation shows the role of a multidisciplinary team of doctors in the treatment of acute kidney injury (AKI) in a patient suffering from bronchial asthma and metabolic syndrome (morbid obesity, arterial hypertension, type 2 diabetes mellitus). The importance of correcting metabolic disorders (diet, self-monitoring of glycemia, urate- and glucose-lowering therapy) has been demonstrated both as part of the complex therapy of AKI and for the prevention/slowing of further kidney damage.
Therapeutic comorbidity – combination of dermatopolymiositis and Weber-Christian panniculitis: a difficult path to diagnosis
Authors:   Omsk State Medical University, Usacheva Elena V. , Gizatulina Olga N. ,   Omsk region "Clinical Diagnostic Center", Dubrovskaya Irina I. ,   Omsk region "City Clinical Emergency Hospital No.2", Nadey Elena V. ,   Omsk State Medical University, Usachev Nikita A. ,   Omsk region "City polyclinic No.4"
Published: June 2024

Comorbid pathology in therapeutic practice is difficult to diagnose, because it often has a complex clinical picture, atypical dynamics of the course of diseases, including those changing under the influence of ongoing therapy. The polysystemic nature of the lesion with an uneven degree of pathological damage to organs and systems can obscure the underlying disease when its symptoms are accepted as a separate disease. At the same time, the insufficient effectiveness of the therapy should make you think about other causes of the pathological process, suspect autoimmune, oncological and rare congenital or genetically determined diseases and syndromes.
Clinical Case A clinical case of Prader–Willi syndrome
Authors:   Kursk State Medical University, Serezhkina Aleksandra V. , Khmelevskaya Irina G. ,   Kursk State Medical University, Razinkova Natalia S. ,   Kursk State Medical University, Minenkova Tatiana A. ,   Kursk State Medical University, Yakovleva Darya R. ,   Kursk State Medical University, Gromov Rostislav E. ,   Kursk State Medical University
Published: June 2024

Relevance. Prader–Willi syndrome (SPW) is a rare genetic disease associated with a predominant legion of the nervous system with subsequent involvement of other systems. The main signs of the syndrome part childhood hypotension, hypogonadism with hypogenitalism, morbid obesity, and impaired cognitive functions. Goal. Presentation of a rare case with consideration of the features of the clinical picture and course of SPW. Materials and methods. The medical history of patient A., 10 months old, who is undergoing examination and inpatient treatment in the 3rd ward. OBUZ ODKB, as well as the materials of the Pubmed platform. Results. The article presents a clinical case of Prader–Willi syndrome in a 10-month-old girl with the first signs in the prenatal period.
Premature heart beats in patients with the connective tissue disease
Authors:   Novosibirsk State Medical University, Miller Olga N.
Published: June 2024

The ventricular heart rhythm disturbances occurring in individuals with no structural heart abnormality are a pressing issue not only due to their significance, but also due to the lack of clear approaches to treatment of such patients. In actual clinical practice, the physician faces a number of unresolved problems related to both causes and treatment of premature heath beats. This issue requires further research aimed to determine the optimal tactics of management for the specific patient with premature heath beats.
«Prescribe not prescribe»: the role of β-blockers in modern treatment of patients with arterial hypertension and concomitant disorders
Authors:   Russian Gerontological Research and Clinical Center, Pirogov Russian National Research Medical University, Gilyarevsky Sergey R. ,   Russian Medical Academy of Continuous Professional Education, Eruslanova Ksenia A. ,   Russian Gerontological Research and Clinical Center, Pirogov Russian National Research Medical University, Bendeliani Nana G. ,   Bakulev National Medical Research Center for Cardiovascular Surgery, Shchedrina Anna Yu. ,   Russian Gerontological Research and Clinical Center, Pirogov Russian National Research Medical University, Golshmid Maria V. ,   Russian Medical Academy of Continuous Professional Education, Tkacheva Olga N. ,   Russian Gerontological Research and Clinical Center, Pirogov Russian National Research Medical University
Published: June 2024

The paper is focused on clarifying the role of using β-blockers in modern treatment of arterial hypertension (AH) in patients with comorbidities. Despite the fact that the majority of clinical guidelines on the treatment tactics for AH consider β-blockers as the drugs prescribed when there are certain additional indications, nowadays an attempt is made to return to the distant past of cardiology, when β-blockers played a role of first line antihypertensive drugs. The paper provides evidence-based arguments in favor of the balanced approach to prescription of β-blockers to patients with AH. At the same time, the paper presents the results of the recent analysis involving the data on the participants of the large randomized trial focused on assessing the effects of dapagliflozin in patients with heart failure and preserved left ventricular ejection fraction suggesting frequent use of β-blockers in clinical practice for patients with AH and concomitant disorders, as well as the β-blockers’ safety and probable efficacy. The paper provides the meta-analysis results allowing one to estimate antihypertensive effect of β-blockers, the use of which makes it possible to reduce systolic blood pressure by almost 8—10 mm Hg. Furthermore, the paper discusses an opportunity to quickly obtain information about the role of certain drugs for treatment of AH using ChatGPT that is considered to be a promising information technology. The paper also provides data on the use of the doses of β-blockers that are not high enough and does not allow to achieve optimal heart rate in clinical practice.
Cardiovascular pathology in HIV-infection during antiretroviral therapy
Authors:   Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology, Tuaeva Renata G. , Tuglanova Bella M. ,   Moscow Medical Center for the Prevention and Control of AIDS, Loseva Olga K. ,   Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology,   Russian Biotechnological University, Zhukova Olga V. ,   Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology,   Patrice Lumumba Peoples' Friendship University of Russia, Nagibina Margarita V. ,   oscow Medical Center for the Prevention and Control of AIDS,   Yevdokimov Moscow State University of Medicine and Dentistry, Bessarab Timur P. ,   Moscow Medical Center for the Prevention and Control of AIDS
Published: June 2024

A cardiac examination (ECG, Echo-CG and BCA ultrasound) was carried out on 150 patients – 60 HIV-infected with various stages of the disease and 90 patients with syphilis/HIV co-infection. Cardiovascular pathology caused by HIV infection was detected in 46.6% of patients in the first group, and in 7.7% in the second group. In a comparative analysis of the effect of antiretroviral therapy (ART) among those examined, it was proven that in the absence of ART or delayed or irregular use of drugs, the proportion of patients with cardiovascular pathology is several times higher than that of people who took ART on a timely and regular basis.
Therapeutic avenues and prospects of blood glucose self-monitoring, the essential component of diabetes mellitus management
Authors:   Russian University of Medicine, Biryukova Elena V.
Published: June 2024

Diabetes mellitus (DM) is one of the global problems of world’s healthcare. Systemic vascular complications are the dangerous sequelae of the disease, and chronic hyperglycemia is the leading factor contributing to the disease development. Glycemic control remains an effective strategy to prevent diabetes complications that requires achieving and maintaining metabolic targets throughout the life of the patient. The current guidelines on the selection of personalized treatment goals based on the glycated hemoglobin (HbA1c) levels and the glycemic control methods are discussed. The emphasis is placed on self-monitoring of blood glucose (SMBG), one of the important factors contributing to the efficacy of the ongoing glucose-lowering therapy and hypoglycemia prevention. Proper SMBG is impossible without therapeutic training of DM patients. The current understanding of SMBG implies a certain frequency of the systematic measurement of blood glucose levels depending on the DM type and the type of glucose-lowering therapy. Various glucose meters for measurement of blood glucose levels at home are available. The criteria for choosing the glucose meter include compliance with the relevant accuracy standards, simplicity and ease of use, ease of getting the results by patients, which allow patients of any age to easily measure blood glucose levels. With all the advancements in modern technology, the glucose meters have appeared that significantly expand the possibilities of DM control due to integration with the free mobile application.
Comorbidity and «masks» in neurology
Authors:   Voronezh region Voronezh City Clinical Polyclinic No. 4, Lushchik Arina L. , Firsova Irina A. ,   Voronezh Regional Clinical Consultative and Diagnostic Center, Panina Olga A. ,   Burdenko Voronezh State Medical University
Published: June 2024

The purpose of the study is to demonstrate the difficulties faced by a primary care physician at the time of diagnosis in making a diagnosis and the need for medical compliance for the proper management of patients with comorbid pathology. Materials and methods. 3 clinical cases of patients examined from complaints and objective data to laboratory and instrumental examination methods are presented. Analysis of patient outpatient records under observation and treated at the Voronezh City Clinical Polyclinic No. 4. Study of the provided medical documentation, anamnesis data, and conclusions of specialist doctors. The results of ECG, EEG, ultrasound, MRI and RCT of the brain, ENMG, CT of the OGK, and laboratory data were analyzed. Results. The importance of the clinical picture totality in every case, close attention to routine blood tests in the practice of a neurologist, the importance of the data obtained together and separately, close cooperation with related specialists as part of the medical commission is shown. Conclusion. Neurological manifestations of the disease occur in various other pathologies. Therefore, it is very important to take into account all deviations when examining a patient, since sometimes the true diagnosis is masked by other diseases. Only an integrated approach in the examination of patients with complex cases allows us to make a correct diagnosis and conduct adequate therapy.
The case of a girl named Misha: shocking, masking and neurodivergence
Authors:   Kazan State Medical University, Mendelevich Vladimir D. , Nesterina Maria K. ,   Kazan State Medical University, Konovalova Veronika N. ,   Kazan State Medical University, Mitrofanov Ivan A. ,   Kazan State Medical University
Published: June 2024

The article presents the case of a girl, Arina, who, based on psychological self-examination, discovered that she had autism spectrum disorder and insisted on receiving an official psychiatric diagnosis. She reported that for many years she had been engaged in masking – hiding existing communication disorders, as a result of which she developed emotional dysregulation and “autistic burnout.” In addition, she was dissatisfied with her name and asked those around her to call her Misha, but in the feminine gender. Misha's behavior was disharmonious; she was prone to conflict due to a misunderstanding of the non-verbal reactions of her interlocutors. An analysis of the literature on the issue of comorbidity of autism spectrum disorders was carried out. It was concluded that the Asperger syndrome identified in the patient was not combined with clearly defined comorbid mental and behavioral disorders, but with abortifacient elements of certain psychopathological symptoms. It is assumed that comorbid disorders did not develop in Misha in an expanded form precisely because of the presence of specific autistic traits that made it difficult to develop a full picture of any other disorders.
Modern trends of blood glucose self-monitoring
Authors:   Endocrinological Dispensary of the Moscow Healthcare Department, Antsiferov Mikhail B. ,   Russian Medical Academy of Continuous Professional Education, Koteshkova Olga M. ,   Endocrinological Dispensary of the Moscow Healthcare Department, Antsiferova Daria M. ,   Russian Medical Academy of Continuous Professional Education, Demidov Nikolay A. ,   SBHI Moscovskii City Hospital, Department of Healthcare of Moscow
Published: June 2024

Objective. To consider modern means of monitoring glycemia using a mobile application that allows remote control of diabetes mellitus (DM). The main provisions. The problem of self-control of DM in the modern world does not lose relevance. Recommendations on the management of patients with DM are updated annually. New approaches to self-monitoring of glycemia are being developed, innovative glucose meters are being introduced, which are a system with a mobile application.