bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS TATA LETAK RECLOSER MENGGUNAKAN METODE PENELETIAN STATISTIKA BEBAN DAN POPULASI GUNA MEMAKSIMALKAN KINERJA SISTEM
Authors: Adiba Farda Akhyal , Abidin Zainal , Suharijanto Suharijanto
Published: February 2018

Disturbance at PT. PLN (Persero) Rayon Sidayu Area Gresik Distribution East Java is quite diverse, most of the disturbance that occurred was temporary temporary, the cause is not known and to minimize the disturbance is widely used automatic cover (recloser) on the electricity distribution network. The placement of the recloser is only based on a safe distance without consideration of the load and the customer population and calculation of the layou t for the determination of the location that can maximize the system performance. By knowing the burden and the customer population it will be able to know how many losses and the number of customers who will experience a disruption when the recloser has failed function due to improper layout, load and customer population can also

be a variable to calculate SAIFI value. One parameter of failure (the extent of failure or blackout to the customer) in the electrical world is the value of SAIFI (System Average Interruption Frequency Index). Higher values indicate an increasing rate of failure. In this analysis there are 3 points that

counted SAIFInya value that is point 19 with SAIFI value 15.1, point 18 with SAIFI value 61,7 and point 12 with value SAIFI 137,2. from the calculation of each point can get the result of SAIFI minimum disturbance index that is at point 19.
SISTEM INFORMASI RAWAT INAP PASIEN PADA RUMAH SAKIT BEDAH MITRA SEHAT DENGAN MENGGUNAKAN VISUAL BASIC
Authors: Mauladi Kemal Farouq
Published: February 2018

Information system patient at hospital of healthy partner surgery is one kind of software that can be used to assist administration process, registration and data processing at one of ins titution which move in public service area. In this research will be made an inpatient information system
using Visual Basic programming language. The amount of data and the need for rapid information delivery in the administration of payment services and data collection of patients using information technology as a medium that is considered capable and reliable to assist in data processing and presentation of information fast, easy and accurate.
STUDI PENGARUH PENAMBAHAN ABU SEKAM PADI TERHADAP KUAT TEKAN BETON
Authors: Samsudin Samsudin , Hartantyo Sugeng Dwi
Published: February 2018

Rice husk is the waste from the rice mill has a dominant silica content that is equal to 93%

and almost the same content of silica contained in the microsilica manufactured. By its nature when

mixed into the concrete mix will improve the characteristics of concrete. In this research, rice husk ash

was added to the concrete mixture of Fc 'K-175 Kg / cm2 with a variation of 0%, 8%, 10%, and 12%

husk ash ash taken based on the weight of cement. This research aims to determine the value of concrete

compressive strength achieved from rice husk ash mixture in K-175 Kg / cm2 concrete. Concrete mortar

design using ASTM method. Test specimens were made for each addition of the percentage of husk ash

is as much as 3 samples, with cylinder mold size 15 cm diameter with height 30 cm. Based on Table

4:22 in the results obtained that there is a decrease in strength on each addition of ash rice husk level.

It is known that the normal compressive strength of 28 days old concrete is 226,47 kg / m2 and the

lowest compressive strength is in the addition of rice husk ash 12% age 28 day that is 129,41 kg / m2
SISTEM INFORMASI PENILAIAN KINERJA PEGAWAI PADA KANTOR KECAMATAN SUKODADI DI KABUPATEN LAMONGAN DENGAN METODE AHP DAN BOOTSTRAP
Authors: Diana Sundiya Eryfa , Wahyudi M Hasan , Rohman M Ghofar
Published: February 2018

So far, the employee performance assessment at the office of sukodadi sud district in lamongan regency is conducted by the appraisal officer in coordination with the Head Office. Previously was done manual calculation without using a system. The calculation carried out in the form of determination of eligibility fulfillment of promotion of employee. Decision support systems can

assist in determining assessments of employee work for the purpose of regular promotion by using a method. The existence method can be used in decision support systems such as Analytical Hierarchi Process (AHP). Systematic and appropriate in the decision-making process that is able to show the value of the competence of employees in accordance with the criteria established by the Office or decision makers based on systematic data analysis for the purpose of promotion of regular.
APLIKASI SIMULASI MEMBUAT SIM C BERBASIS ANDROID
Authors: Anam Achmad Syaiful , Wardhani Retno , Masruroh Masruroh
Published: February 2018

Driving license is a registration proof and identification that is given by Indonesian Nation Police to

someone who is fulfilled the administrative requirement, physically and mentally healthy, understand

the traffic regulation, and skilled motorcycle driving. The survey result shows that not all people who

have motorcycle have C driving license, eight of ten people say that they are afraid and have not

understood the procedure of making C driving license yet. The motorcycle driver ha ve not passed the

C driving license test frequently because they have not understood the theory of traffic sign and road

marking, and driving the motorcycle yet. Based on that problem C Driving license Simulation

Application Android Based is made as the research tittle. This application is developed based on

Construct 2, the stages of developing Application is started from collecting the data (color-blind test,

theory test, practice test’s information, and driving license information), then designing the pr ogram’s

interface and program system’s groove, and the last one is black box testing and user testing. The

implementation result of internal test (developing) Application test is based on Black Box method.

Implementation result of user test based on the qu estionnaire from 50 respondents used likert scale

was gotten 89%. So, it can be concluded that C Driving license Simulation Application is the good

one
Implementasi Lean Six Sigma Dalam Penentuan Prioritas Perbaikan Kualitas Pelayanan Padarumah Sakit Di Kabupaten Lumajang
Authors: Ato’illah Mohammad , Hartono Hartono
Published: February 2018

Penelitian bertujuan menentukan prioritas perbaikan kualitas pelayanan rumah sakit berdasarkan persepsi, harapan dan tingkat kepentingan pelanggan dengan menggunakan pendekatan lean six sigma. Hasil penelitian   diharapkan   dapat   memberikan   kontribusi   bagi   pengelola   rumah   sakit   dalam   memberikan pelayanan terbaik bagi masyarakat. Penelitian  ini menentukan prioritas perbaikan kualitas pelayanan rumah sakit berdasarkan  dimensi kualitas  pelayanan  yang terdiri dari (1) keterwujudan  (tangible),  (2) kehandalan (reliability),  (3) daya tanggap (reponsiveness),  (4) jaminan (assurance) dan (5) empati (emphaty). Penelitian ini merupakan  penelitian  deskriptif  kualitatif  dimaksudkan  untuk  menganalisis  tanggapan  responden  atas kualitas pelayanan rumah sakit berdasarkan  persepsi, harapan dan kepentingan  yang akan digunakan  untuk menentukan  prioritas  perbaikan  kualitas pelayanan rumah sakit. Responden  penelitian  sebanyak 240 orang pengguna  jasa  pada  empat  rumah  sakit  di  Kabupaten   Lumajang.  Teknik  analisis  data  menggunakan pendekatan  lean  six sigma  dengan  terlebih  dulu  menguji  instrument  penelitian  dengan  uji  validitas  dan reliabilitas. Hasil penelitian terdapat perbedaan urutan prioritas perbaikan kualitas layanan pada empat rumah sakit.   Prioritas   perbaikan   pada   rumah   sakit   Dr.   Haryoto   adalah   kemampuan   dan   kecekatan   dalam menghadapi  keluhan pasien, pada rumah sakit Bhayangkara  adalah ketepatan  waktu buka loket pelayanan, pada rumah sakit Wijaya Kusuma adalah kelengkapan  peralatan  pemeriksaan,  dan pada rumah sakit Islam adalah kemampuan petugas menjelaskan hasil pemeriksaan
Pengujian Metode Fuzzy Time Series Chen dan Hsu Untuk Meramalkan Nilai Indeks Bursa Saham Syariah Di Jakarta Islamic Index (JII)
Authors: Zulfikar Rizka , Ade`Mayvita Prihatini
Published: February 2018

This research is an  empirical  study to tested  the accuracy  of Chen  and  Hsu’s  Fuzzy Time Series Method used to forecast  sharia  market  stock index in Jakarta Islamic  Index. The data  used in this research are  secondary  data  consists of daily stock market indexes during  23 November 2016 to 14 July 2017.  Chen dan Hsu’s Fuzzied Series Method used in this research has the smallest MSE (Mean Square Error)  and AFER (Average Forecasting Error  Rate) value rather  than others method such as Song and Chrissom (1993). Song and Chrissom (1994), Chen (1996), Hwang, Chen and Lee (1998), Huarng  (2001)  and  Chen (2002). To tested  the accuracy  of the Chen’s  dan  Hsu’s Fuzzied Series. Method researcher has to do 5 (five) steps such as (1) Determine lag between historical  data, interval and The Universe Data  (U), (2) Distributing  Data  into The Unniverse,  (3) Define The Fuzzy Set, (4) Determine The Fuzzy Logical Relationship (FLR), and (5) Analyse the Difference between data. There are 3 (three) rules in Chen’s dan Hsu’s Fuzzied Series Method based on the Difference and FLR.  The result of this research is Chen dan Hsu’s Fuzzied Series Method has MSE = 1.88 and AFER =0.006% and  it can  be used to make forecasting  on value and trend  sharia  stock market  in Jakarta  Islamic index.
Sheath Structure in Oxygen Plasma for Different Presheath Plasma Density
Authors: Kaphle Vikash , Khanal Raju
Published: February 2018

Zinc oxide films are used as transparent conductive electrode for preparing organic light-emitting devices. In plasma-enhanced vapor deposition oxygen plasma is formed which then react with zinc atoms forming zinc oxide plasma, which is then deposited to the substrate. Hence, the proper understanding of the oxygen plasma-wall interaction is of crucial importance because of its application in plasma depositions. We have studied the sheath structure in oxygen plasma formed in front of an absorbing material wall for different density at the presheath side. We have used a kinetic trajectory simulation model to simulate the oxygen plasma. It has been observed that the sheath structure is highly affected by the plasma density at the presheath side. Hence, the densities of particles reaching the wall can be controlled by adjusting the presheath plasma density which is the key to thin film deposition.Keywords: Plasma; Sheath; Presheath; Quasineutrality; Bohm criterionThe Himalayan Physics Vol.1, No.1, May, 2010Page: 10-13Uploaded Date: 28 July, 2011
Many Body Interactions and Lattice Dynamics of Gold
Authors: Thapa S.R.B.
Published: February 2018

Lattice dynamics of gold is studied theoretically using phenomenological model. This model considers (i ion-ion and (ii) ionelectron interactions to evaluate the potential energy. Contribution to ion-ion interaction is the sum of two body central interactions between ions and many body interactions among ions. Contribution to potential energy due to ion-electron interactions is evaluated using screened coulomb potential. Using this model phonon frequencies of gold are computed at 48 non-equivalent points of Brillouin zones of crystal and compared with experimental points. Lattice specific heats at different temperatures are evaluated by dividing the frequency spectrum in interval of 0.1 tiga hertz. Using the computed values of lattice specific heats, Debye characteristic temperatures of gold are computed. The model is used to calculate compressibility and Poission's ratio. Agreement of theoretical calculations with experimental results is satisfactory.Key words: Ion-ion interaction; Ion-electron interaction; Phonon frequency; Lattice specific heat; Debye characteristic temperatureThe Himalayan Physics Vol.1, No.1, May, 2010Page: 44-47Uploaded Date: 28 July, 2011
A new Frontier: Nano-Science and Engineering
Authors: Lamichhane Sanjita , Lamichhane S K
Published: February 2018

Not available.Key words: Nano scienceThe Himalayan Physics Vol.1, No.1, May, 2010 Page: 58-61 Uploaded Date: 28 July, 2011
An Experimental Study on Dielectric Relaxor Behavior of the System (Pb1-xBax ) ZrO3 (x = 0.25, 0.30, 0.35) Ceramics
Authors: Subedi Ratna Mani
Published: February 2018

Not available.Key words: Dielectric Relaxor BehaviorThe Himalayan Physics Vol.1, No.1, May, 2010 Page: 73-76 Uploaded Date: 29 July, 2011
Optical Communication
Authors: Rayamajhi Kamal Bahadur
Published: February 2018

Not available.Key words: Optical CommunicationThe Himalayan PhysicsVol.1, No.1, May, 2010 Page: 77-78 Uploaded Date: 29 July, 2011
The Foreground of Big Bang Nucleosynthesis
Authors: Karki Ravi
Published: February 2018

Not available.Key words: Big Bang NucleosynthesisThe Himalayan Physics Vol.1, No.1, May, 2010 Page: 79-82 Uploaded Date: 29 July, 2011
Entropy and Existence of Universe
Authors: Subedi Chetan
Published: February 2018

Not available.Key words: UniverseThe Himalayan Physics Vol.1, No.1, May, 2010 Page: 89-89 Uploaded Date: 28 July, 2011
A Brief Introduction of Paradox in Physics
Authors: Dahal Narayan Prasad
Published: February 2018

Not available.Key words: ParadoxThe Himalayan PhysicsVol.1, No.1, May, 2010 Page: 93-95 Uploaded Date: 29 July, 2011
Albert Einstein and Relativity
Authors: Khatri Kamal B
Published: February 2018

Not available.Key words: RelativityThe Himalayan Physics Vol.1, No.1, May, 2010 Page: 99-100 Uploaded Date: 29 July, 2011
Vegetation Analysis of Namuna Community Forest of Salbari, Sanischare VDC in Jhapa District, Eastern Nepal
Authors: Bhattarai Krishna Prasad
Published: February 2018

Vegetation study was carried out in an afforested land called Namuna Community Forest in Salbari, Sanischare, VDC, Jhapa, District. Random samplings for estimation of density, frequency, basal area and IVI were carried out by laying quadrates (10m x 10 m) at different sites of forest, three times and mean value was calculated. Nine tree species were recorded during field study. Total density of 10,410 pl/ha and total basal area of 33.956 m2/ha of tree species were recorded. The value of density (1790 pl/ha), basal area (31.45m2/ha) and IVI (130.63) were found highest for Shorea robusta, which is ecologically successful species in this forest. Lower value of basal area showed that this forest is young and regenerating. Other tree species had comparatively lower value of density, basal area and IVI due to regular human inte rference. Therefore an example of establishing forest community so as to initiate the conservation of local biodiversity has been discussed in this article.Key words: Community forest; conservation; IVI estimation; regenerating; Shorea robustaJournal of Natural History Museum Vol. 23, 2008 Page 12-15
A Diversity Account of Bryaceae (Bryophyta: Musci) of Nepal
Authors: Pradhan Nirmala , Joshi Sanu Devi
Published: February 2018

Bryums are diverse mosses distributed widely throughout the country. The species diversity of Bryaceae which were documented in various periods has been presented here. This paper includes 82 species including three subspecies and five varieties under seven genera of the total recorded 1150 bryofloral species in Nepal so far. Besides published records, the field survey of the first author within last five years has also been included here.Key words: Bryoflora; cosmopolitan; diversity; distribution; speciesJournal of Natural History Museum Vol. 23, 2008 Page 19-26
Distribution and Status of Highland Mushrooms: A Study from Dolpa, Nepal
Authors: Devkota Shiva
Published: February 2018

This study comprises report on mycological exploration in 2006 at the most remote and highland district, Dolpa of Western Nepal. The study area was virgin for mushrooms study. Forty four species were collected, out of which 40 are new to the area. The collected species are parasitic, saprophytic and mycorrhizal associates' in habitat. Locally 22 and five species were used for culinary and medicinal values respectively. Cordyceps sinensis, Morchella conica, M. esculenta, Laetiporus sulphureus, Agaricus bisporus, Termitomyces clypeatus and Cantharellus cibarius are most popular and potential resources from the study sites.Key words: Caterpillar fungus; Dolpa; macrofungi; morels mushrooms; NepalJournal of Natural History Museum Vol. 23, 2008 Page 51-59
Ethnomycological Knowledge and Nutritional Analysis of Some Wild Edible Mushrooms of Sagarmatha National Park (SNP), Nepal
Authors: Giri Anjana , Rana Rabina
Published: February 2018

This paper describes the traditional mycological knowledge of Sherpa community of Sagarmatha National Park (SNP) and its adjoining areas (2600-4000 masl). Twenty nine species were identified having ethnomycological use. Among which 26 were identified as edible, 2 as medicine and 1 for decorative purposes. The local communities are well familiar about the morphological feature, habitat and qualities of these mushrooms. The local names of mushrooms have been derived on the basis of their morphological features, nature of growth and colour. The indexes of similarity of edible mushrooms along different forest range from 40-80%. Proximate composition (moisture, ash carbohydrate, crude fat, crude protein and crude fibre) and mineral composition (calcium, phosphorous and iron) of 11 most prized edible mushrooms was investigated. The overall nutritional values of wild edible mushrooms analyzed were good and comparable to other cultivated varieties of mushrooms.Key words: Ethnomycology; edible; mushrooms; nutrition; proteinJournal of Natural History Museum Vol. 23, 2008 Page 65-77
Diversity and Status of Butterflies in Lowland Districts of West Nepal
Authors: Khanal Bhaiya
Published: February 2018

This paper is an outcome of the studies made in four districts (Dangdeukhuri, Banke, Bardia and Surkhet) of western Terai in different months of various years. Altogether 85 species categorized into 64 genera and 10 families have been reported with their status categories based on national status list. The process of urbanization has altered valuable natural habitats of many of the rare species especially in Banke and Dangdeukhuri districts. Monitoring process under the established regulation and thorough investigations in many unexplored areas of this region have been felt essential so to design suitable conservation measures to butterflies of this region.Key words: Biodiversity; western terai; butterflies; unexplored; habitatsJournal of Natural History Museum Vol. 23, 2008 Page 92-97
Experimental and FE Modeling of Mixed-Mode Crack Initiation Angle in High Density Polyethylene
Authors: Zerrouki Abdelwahab , Boulenouar Abdelkader , Mazari Mohamed , Benguediab Mohamed
Published: February 2018

In this paper, an experimental and a numerical analysis were carried out using High density polyethylene (HDPE). Sheets with an initial central crack (CCT specimens) inclined with a given angle are investigated and compared to the loading direction. The kinking angle is experimentally predicted and numerically evaluated under mixed mode (I+II), as a function of the strain energy density (SED) around the crack-tip, using the Ansys Parametric Design Language (APDL).According to the experimental observations and numerical analysis, the plan of crack propagation is perpendicular to the loading direction. Moreover, as suggested by Sih in the framework of linear elastic fracture mechanics (LEFM), the minimum values Sminof the factor S are reached at the points corresponding to the crack propagation direction. These results suggest that the concept of the strain energy- density factor can be used as an indicator of the crack propagation direction.
Cropping Systems and Climate Change in Humid Subtropical Environments
Authors: Hernandez-Ochoa Ixchel , Asseng Senthold
Published: February 2018

In the future, climate change will challenge food security by threatening crop production. Humid subtropical regions play an important role in global food security, with crop rotations often including wheat (winter crop) and soybean and maize (summer crops). Over the last 30 years, the humid subtropics in the Northern Hemisphere have experienced a stronger warming trend than in the Southern Hemisphere, and the trend is projected to continue throughout the mid- and end of century. Past rainfall trends range, from increases up to 4% per decade in Southeast China to −3% decadal decline in East Australia; a similar trend is projected in the future. Climate change impact studies suggest that by the middle and end of the century, wheat yields may not change, or they will increase up to 17%. Soybean yields will increase between 3% and 41%, while maize yields will increase by 30% or decline by −40%. These wide-ranging climate change impacts are partly due to the region-specific projections, but also due to different global climate models, climate change scenarios, single-model uncertainties, and cropping system assumptions, making it difficult to make conclusions from these impact studies and develop adaptation strategies. Additionally, most of the crop models used in these studies do not include major common stresses in this environment, such as heat, frost, excess water, pests, and diseases. Standard protocols and impact assessments across the humid subtropical regions are needed to understand climate change impacts and prepare for adaptation strategies.
Identification of Key Pathways and Genes in the Dynamic Progression of HCC Based on WGCNA
Authors: Yin Li , Cai Zhihui , Zhu Baoan , Xu Cunshuan
Published: February 2018

Hepatocellular carcinoma (HCC) is a devastating disease worldwide. Though many efforts have been made to elucidate the process of HCC, its molecular mechanisms of development remain elusive due to its complexity. To explore the stepwise carcinogenic process from pre-neoplastic lesions to the end stage of HCC, we employed weighted gene co-expression network analysis (WGCNA) which has been proved to be an effective method in many diseases to detect co-expressed modules and hub genes using eight pathological stages including normal, cirrhosis without HCC, cirrhosis, low-grade dysplastic, high-grade dysplastic, very early and early, advanced HCC and very advanced HCC. Among the eight consecutive pathological stages, five representative modules are selected to perform canonical pathway enrichment and upstream regulator analysis by using ingenuity pathway analysis (IPA) software. We found that cell cycle related biological processes were activated at four neoplastic stages, and the degree of activation of the cell cycle corresponded to the deterioration degree of HCC. The orange and yellow modules enriched in energy metabolism, especially oxidative metabolism, and the expression value of the genes decreased only at four neoplastic stages. The brown module, enriched in protein ubiquitination and ephrin receptor signaling pathways, correlated mainly with the very early stage of HCC. The darkred module, enriched in hepatic fibrosis/hepatic stellate cell activation, correlated with the cirrhotic stage only. The high degree hub genes were identified based on the protein-protein interaction (PPI) network and were verified by Kaplan-Meier survival analysis. The novel five high degree hub genes signature that was identified in our study may shed light on future prognostic and therapeutic approaches. Our study brings a new perspective to the understanding of the key pathways and genes in the dynamic changes of HCC progression. These findings shed light on further investigations
Discovery of 2-(4-Substituted-piperidin/piperazine-1-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-quinazoline-2,4-diamines as PAK4 Inhibitors with Potent A549 Cell Proliferation, Migration, and Invasion Inhibition Activity
Authors: Wu Tianxiao , Pang Yu , Guo Jing , Yin Wenbo , Zhu Mingyue , Hao Chenzhou , Wang Kai , Wang Jian , Zhao Dongmei , Cheng Maosheng
Published: February 2018

A series of novel 2,4-diaminoquinazoline derivatives were designed, synthesized, and evaluated as p21-activated kinase 4 (PAK4) inhibitors. All compounds showed significant inhibitory activity against PAK4 (half-maximal inhibitory concentration IC50 < 1 μM). Among them, compounds 8d and 9c demonstrated the most potent inhibitory activity against PAK4 (IC50 = 0.060 μM and 0.068 μM, respectively). Furthermore, we observed that compounds 8d and 9c displayed potent antiproliferative activity against the A549 cell line and inhibited cell cycle distribution, migration, and invasion of this cell line. In addition, molecular docking analysis was performed to predict the possible binding mode of compound 8d. This series of compounds has the potential for further development as PAK4 inhibitors for anticancer activity.
Half-Sandwich Ru(II) and Os(II) Bathophenanthroline Complexes Containing a Releasable Dichloroacetato Ligand
Authors: Štarha Pavel , Trávníček Zdeněk , Vančo Ján , Dvořák Zdeněk
Published: February 2018

We report on the preparation and thorough characterization of cytotoxic half-sandwich complexes [Ru(η6-pcym)(bphen)(dca)]PF6 (Ru-dca) and [Os(η6-pcym)(bphen)(dca)]PF6 (Os-dca) containing dichloroacetate(1–) (dca) as the releasable O-donor ligand bearing its own cytotoxicity; pcym = 1-methyl-4-(propan-2-yl)benzene (p-cymene), bphen = 4,7-diphenyl-1,10-phenanthroline (bathophenanthroline). Complexes Ru-dca and Os-dca hydrolyzed in the water-containing media, which led to the dca ligand release (supported by 1H NMR and electrospray ionization mass spectra). Mass spectrometry studies revealed that complexes Ru-dca and Os-dca do not interact covalently with the model proteins cytochrome c and lysozyme. Both complexes exhibited slightly higher in vitro cytotoxicity (IC50 = 3.5 μM for Ru-dca, and 2.6 μM for Os-dca) against the A2780 human ovarian carcinoma cells than cisplatin (IC50 = 5.9 μM), while their toxicity on the healthy human hepatocytes was found to be IC50 = 19.1 μM for Ru-dca and IC50 = 19.7 μM for Os-dca. Despite comparable cytotoxicity of complexes Ru-dca and Os-dca, both the complexes modified the cell cycle, mitochondrial membrane potential, and mitochondrial cytochrome c release by a different way, as revealed by flow cytometry experiments. The obtained results point out the different mechanisms of action between the complexes.
A Comparative Study of Human Saposins
Authors: Garrido-Arandia María , Cuevas-Zuviría Bruno , Díaz-Perales Araceli , Pacios Luis
Published: February 2018

Saposins are small proteins implicated in trafficking and loading of lipids onto Cluster of Differentiation 1 (CD1) receptor proteins that in turn present lipid antigens to T cells and a variety of T-cell receptors, thus playing a crucial role in innate and adaptive immune responses in humans. Despite their low sequence identity, the four types of human saposins share a similar folding pattern consisting of four helices linked by three conserved disulfide bridges. However, their lipid-binding abilities as well as their activities in extracting, transporting and loading onto CD1 molecules a variety of sphingo- and phospholipids in biological membranes display two striking characteristics: a strong pH-dependence and a structural change between a compact, closed conformation and an open conformation. In this work, we present a comparative computational study of structural, electrostatic, and dynamic features of human saposins based upon their available experimental structures. By means of structural alignments, surface analyses, calculation of pH-dependent protonation states, Poisson-Boltzmann electrostatic potentials, and molecular dynamics simulations at three pH values representative of biological media where saposins fulfill their function, our results shed light into their intrinsic features. The similarities and differences in this class of proteins depend on tiny variations of local structural details that allow saposins to be key players in triggering responses in the human immune system.
Microhydration and the Enhanced Acidity of Free Radicals
Authors: Walton John C.
Published: February 2018

Recent theoretical research employing a continuum solvent model predicted that radical centers would enhance the acidity (RED-shift) of certain proton-donor molecules. Microhydration studies employing a DFT method are reported here with the aim of establishing the effect of the solvent micro-structure on the acidity of radicals with and without RED-shifts. Microhydration cluster structures were obtained for carboxyl, carboxy-ethynyl, carboxy-methyl, and hydroperoxyl radicals. The numbers of water molecules needed to induce spontaneous ionization were determined. The hydration clusters formed primarily round the CO2 units of the carboxylate-containing radicals. Only 4 or 5 water molecules were needed to induce ionization of carboxyl and carboxy-ethynyl radicals, thus corroborating their large RED-shifts.
Gold and Nickel Extended Thiophenic-TTF Bisdithiolene Complexes
Authors: Silva Rafaela , Vieira Bruno , Andrade Marta , Santos Isabel , Rabaça Sandra , Lopes Elsa , Coutinho Joana , Pereira Laura , Almeida Manuel , Belo Dulce
Published: February 2018

Gold and nickel bisdithiolene complexes with methyl and tert-butyl substituted thiophenetetrathiafulavalenedithiolate ligands (α-mtdt and α-tbtdt) were prepared and characterized. These complexes were obtained, under anaerobic conditions, as tetrabutylammonium salts. The diamagnetic gold monoanion (n-Bu4N)[Au(α-mtdt)2] (3) and nickel dianionic species (n-Bu4N)x[Ni(α-mtdt)2] (x = 1,2) (4) were similar to the related non-substituted extended thiophenic-TTF (TTF = tetrathiafulvalene) bisdithiolenes. However the introduction of the large, bulky substituent tert-butyl, led to the formation of a Au (I) dinuclear complex, (n-Bu4N)2[Au2(α-tbtdt)2] (5). The neutral methyl substituted gold and nickel complexes were easily obtained through air or iodine exposure as polycrystalline or amorphous fine powder. [Au(α-mtdt)2] (6) and [Ni(α-mtdt)2] (7) polycrystalline samples display properties of a metallic system with a room temperature electrical conductivity of 0.32 S/cm and ≈4 S/cm and a thermoelectric power of ≈5 µV/K and ≈32 µV/K, respectively. While [Au(α-mtdt)2] (6) presented a Pauli-like magnetic susceptibility typical of conducting systems, in [Ni(α-mtdt)2] (7) large magnetic susceptibilities indicative of high spin states were observed. Both electric transport properties and magnetic properties for gold and nickel [M(α-mtdt)2] are indicative that these compounds are single component molecular conductors.
The Microbial Zoo in the C. elegans Intestine: Bacteria, Fungi and Viruses
Authors: Jiang Hongbing , Wang David
Published: February 2018

C. elegans is an invaluable model organism that has been a driving force in many fundamental biological discoveries. However, it is only in the past two decades that it has been applied to host–pathogen interaction studies. These studies have been facilitated by the discoveries of natural microbes that infect C. elegans, including bacteria, fungi and viruses. Notably, many of these microbes share a common site of infection, the C. elegans intestine. Furthermore, the recent descriptions of a natural gut microbiota in C. elegans raise the possibility that this could be a novel model system for microbiome and trans-kingdom interaction studies. Here we review studies of C. elegans host–microbe interactions with a particular focus on the intestine.
Fabrication and photoactivity of ionic liquid–TiO2 structures for efficient visible-light-induced photocatalytic decomposition of organic pollutants in aqueous phase
Authors: Gołąbiewska Anna , Paszkiewicz-Gawron Marta , Sadzińska Aleksandra , Lisowski Wojciech , Grabowska Ewelina , Zaleska-Medynska Adriana , Łuczak Justyna
Published: February 2018

To investigate the effect of the ionic liquid (IL) chain length on the surface properties and photoactivity of TiO2, a series of TiO2 microspheres have been synthesized via a solvothermal method assisted by 1-methyl-3-octadecylimidazolium chloride ([ODMIM][Cl]) and 1-methyl-3-tetradecylimidazolium chloride ([TDMIM][Cl]). All as-prepared samples were characterized by X-ray powder diffraction (XRD), X-ray photoelectron spectroscopy (XPS), diffuse reflectance spectroscopy (DRS), scanning transmission microscopy (STEM) and the Brunauer–Emmett–Teller (BET) surface area method, whereas the photocatalytic activity was evaluated by the degradation of phenol in aqueous solution under visible light irradiation (λ > 420 nm). The highest photoefficiency (four times higher than pristine TiO2) was observed for the TiO2 sample obtained in the presence of [TDMIM][Cl] for a IL to TiO2 precursor molar ratio of 1:3. It was revealed that interactions between the ions of the ionic liquid and the surface of the growing titanium dioxide spheres results in a red-shift of absorption edge for the IL–TiO2 semiconductors. In this regard, the direct increase of the photoactivity of IL–TiO2 in comparison to pristine TiO2 was observed. The active species trapping experiments indicated that O2•− is the main active species, created at the surface of the IL–TiO2 material under visible-light illumination, and is responsible for the effective phenol degradation.
Telephone Appends for Address-Based Samples— An Introduction
Authors: Harter Rachel M. , McMichael Joseph P. , Brown Derick S. , Amaya Ashley , Buskirk Trent D. , Malarek David
Published: February 2018

Surveys with samples selected from an address frame derived from US Postal Service sources are often referred to as address-based sampling (ABS) surveys. For an ABS survey that is primarily conducted by mail, web, or face-to-face, sometimes it is helpful to have a telephone number corresponding to the sample addresses for setting appointments or conducting nonresponse follow-up prompts. The usefulness of a telephone contact mode in a mixed mode ABS design depends on both the percentage of addresses for which telephone numbers can be appended (append rate or match rate) and the accuracy of the telephone numbers associated with addresses. Before planning a telephone contact as part of a mixed-mode study, the designer should know the likely effectiveness of the approach. This paper focuses primarily on append rate information, with a discussion of accuracy rates. For a single ABS frame, telephone match rates vary by geography, address type, match vendor, and by landline vs. cell telephone number. Using very large samples of addresses from a total US ABS frame, we estimated state and national telephone append rates from Marketing Systems Group's sources. The append rates are summarized here and interactively at the website http://abs.rti.org/atlas/.
Refugees of the Black Death: Quantifying rural migration for plague and other environmental disasters
Authors: Borsch Stuart , Sabraa Tarek
Published: February 2018

Deux décennies de travaux sur la Peste noire en Europe et sur la mortalité effrayante qu’elle a causée ont conduit à une ré-évaluation très notable du nombre de victimes. S’il y reste encore beaucoup à découvrir, la mortalité due à la peste noire dans d’autres régions du monde (Proche-Orient, Extrême-Orient, Asie du Sud et Afrique) est, elle, relativement peu étudiée. Bien que nombre de chercheurs aient apporté des contributions significatives à notre compréhension de la mortalité au cours de la seconde pandémie de peste au Moyen-Orient (1347-1844 BC), la mort prématurée de Michael Dols (1977) a fait de ses travaux, à la fois les pionniers et les derniers sur la mortalité durant la Peste noire au Moyen-Orient. Cette étude souhaite relancer ces recherches en abordant la question de la mortalité avec de nouveaux outils. Partant de l’intéressant modèle peste de Keeling et Gilligan (2000) que nous appliquons au nombre de morts enregistrés, modèle que nous avons expérimenté en analysant le cas du Caire dans les années 1400, nous espérons progresser sur cette question en introduisant une nouvelle méthode qui s’appuie sur le caractère typiquement islamique des institutions civiques du Moyen-Orient (institutions qui ont décompté les morts par peste) pour quantifier un phénomène jamais abordé jusqu’à présent (au moins mathématiquement) : celui de la nuée de réfugiés désespérés - innombrables et en majorité ruraux- qui, fuyant la Peste noire, venaient mourir, souvent sans le sou, anonymes et totalement seuls, dans les villes du Moyen-Orient que la plupart d’entre eux n’avaient jamais vues auparavant. Si cette première tentative tient ses promesses, nous espérons être mieux à même de comprendre ce qui semble inexplicable : le nombre astronomique de morts en milieu urbain, qui a rendu toute quantification de la mortalité par peste au Moyen-Orient si difficile.
Bibliothèque imprimée et bibliothèque manuscrite de Gabriel Tarde. Construction et usages d’une base de données à la fin du XIX e siècle
Authors: Salmon Louise
Published: February 2018

La matière documentaire produite et rassemblée par Gabriel Tarde dans sa bibliothèque imprimée et sa bibliothèque manuscrite nous plonge dans une archéologie de la pensée d’un savant à la Belle Époque. Au service de l’énonciation de son système de pensée, Tarde actualise la pratique des adversaria de la Renaissance en mettant en place un dispositif de classement et une méthode de travail qui fonctionnent comme une véritable base de données. À mi-chemin entre la copie et le journal intime, entre le catalogue raisonné de bibliothèque et le brouillon d’une œuvre, Tarde enrichit et utilise cette base de données pendant toute sa vie. Elle alimenta toutes ses réflexions personnelles et toutes ses publications, au point que Tarde en parlait comme de son « cerveau extérieur ».
La bibliothèque de la Société d’économie et de science sociales : les pérégrinations du fonds d’une société savante (1880-2017)
Authors: Savoye Antoine
Published: February 2018

Dès son origine, la bibliothèque de la Société d’économie sociale (devenue, en 1945, Société d’économie et de science sociales) fondée par Le Play se veut un instrument de travail pour les adeptes de sa science sociale. La composition de son fonds, resté de statut privé, reflète l’évolution de ce domaine de recherches et la diversification de ses objets et de ses méthodes. L’étude des pérégrinations de ce fonds, sur près de 140 ans d’existence, éclaire, concrètement, cette évolution en pointant les enjeux scientifiques qu’il a pu représenter pour les différentes institutions d’enseignement et de recherches qui l’ont accueilli.
Eugène Morel : l’odyssée d’un polygraphe au pays de la classification décimale
Authors: Sandras Agnès
Published: February 2018

Pourquoi Eugène Morel, bibliothécaire « à la Nationale », choisit-il d’introduire de manière précoce, avant la Première Guerre mondiale, la classification Dewey dans la bibliothèque populaire de Levallois-Perret ? Cette expérimentation visionnaire, peu encouragée par les pionniers de la classification universelle, trouve ses racines dans la propre histoire de Morel, artiste, écrivain expérimentant une forme de polygraphie, entre romans, articles, pièces de théâtre et écriture qui se voulait scientifique et « bibliothéconomique ». En adaptant la classification Dewey aux besoins d’une bibliothèque populaire, Morel poursuit son rêve de mettre la culture à la portée de tous, et la lutte qu’il s’est assignée de lutter contre les « cimetières de livres » non classés.
Project-Based Organizational Maturity in Architecture, Engineering, and Construction
Authors: Johnson Rick D. , Adkins Joan , Pepper Donna
Published: February 2018

“Theory and practice” seems to be a common phrase in project-based organizations these days due to the academic nature of the work involved in business. This chapter describes the authors' vision for how project-based firms, such as architecture, engineering, and construction organizations, can reach organizational maturity in their respective practices. The chapter articulates the utility of project management maturity models as a necessary means for maturity measurement and growth. Likert-type scales are mentioned as a tool used by consultants to assess organization parameters, as a way of quantifying certain data that can assist with necessary changes. The authors share recommendations in the technology arena, as well as theory research constructs that may help project-based practitioners and companies better understand and apply maturity strategies. These are some of the prime elements in use in these types of organizations because they create value as well as survival enhancements.
A Framework for Understanding the Role of Project Culture for Organizational Project Maturity
Authors: Rincon Ivan Daniel
Published: February 2018

Many factors have been analyzed to qualify objectively the maturity of an organization to execute projects. However, there are other aspects that have to be considered. One of them, closely related to the well-known concept of “organizational culture,” is the “project culture.” Project culture can be defined with analogous elements to those of the organizational culture as a system of shared assumptions, values, and beliefs that govern how people behave towards projects in an organization. Very few studies have been made formally available to understand how organizations culturally face projects as opposed to operational activities. This chapter presents existing literature and augments the evidence through several practical examples. Moreover, this chapter attempts to understand why some organizations, even when aware of their organizational culture, either fail to pass on the culture to project activities or even create a completely different and distinct project culture.
Organizational Success and Failure Criteria in Virtual Team Maturity
Authors: Keil Andrea , Friedrich Ralf , Doppelfeld Dirk
Published: February 2018

As global projects get more complex, virtual teams are established to bring together experts from different fields and cultures. Challenged by different work habits and communication patterns, these teams need fast and effective assessment of their teamwork to install efficient adjustments. In this chapter, the authors introduce an assessment for virtual teamwork based on the virtual team maturity model (VTMM®). The model focuses on internal team processes necessary to compensate for missing face-to-face communication. The VTMM® model defines meta-processes that help create a highly motivated virtual project team, leading to trust, cohesion, and consequently, an improved team performance. In a case study, the authors examine the effects of an VTMM® assessment and implementation of corresponding measures for improvement on virtual team performance. The outcomes are compared to the results of a recent survey on success and failure in virtual team maturity implementation, where project managers from different backgrounds and experience reported their practical observations.
Project and Portfolio Maturity for Waterfall and Agile
Authors: Janssens Jurgen
Published: February 2018

Projects, programs, and portfolios can be safeguards for organizational continuity, enablers of evolutions, or catalysts for change. It is therefore essential to take the maturity into account of the organization they are serving. It is by embedding attention for it on the different levels that the drawbacks of maturity concerns can be turned into micro-catalysts for change, advancement, and success. This chapter analyzes different complementary components of organizational maturity, mainly maturity for program and portfolio management, the maturity of the relation between project and resource management, and maturity on strategy management. The levering potential of maturity risks is briefly be addressed. To give more depth to the silver lining, two cases are integrated. Together, they illustrate that attention for the organizational maturity concern is a concern that goes beyond the differences between traditional Waterfall projects and more agile paced contexts.
How to Design and Frame a Questionnaire
Authors: Farooq Rayees
Published: February 2018

The present chapter explores the essential stages in designing and developing the questionnaires and offers a basic introduction to beginners who are at the preliminary stages of their research. The study was approached purely from a theoretical perspective and various issues and challenges have been addressed including the length of questionnaires, how to distribute a questionnaire and how to analyze the data. The study concluded that researchers often rely on the previously developed questionnaire rather than developing the new one because it requires the knowledge and expertise. For novice researchers, developing entirely a new questionnaire requires a basic understanding of the format of the questionnaire, length of the questionnaire and how to distribute a questionnaire. Therefore, the chapter presents a systematic way to develop a questionnaire keeping in view all the issues and problems faced by researchers who are engaged in study for a thesis or in other research projects.
Scientograph-Based Visualization of Computer Forensics Research Literature
Authors: Mohamed Jahir Hussain Haneefa
Published: February 2018

Studying the communication pattern of scientific information produced as a result of academic and industrial research using mapping techniques is part of scientometric studies. In this chapter, the bibliographic data related to computer forensics retrieved from SCOPUS is subjected to mapping and visualizing. The results showed that the computer forensics literature grows exponentially. USA ranks first among the countries contributing to the literature growth. The University of South Australia is top ranking institution and K.K.R. Choo is the top-ranking author. Conference proceedings are the dominant form of communication flow. The scientograph of keywords reveals six clusters and the keywords with high frequency of occurrences are computer crime, security of data, network security, electronic crime countermeasures, digital forensic, internet, cryptography, cloud computing, cyber security, malware, and intrusion detection.
A Scientometric Profile of Vikram Sarabhai Space Center (VSSC) Based on Scopus Database
Authors: Vijayakumar M. , Stephen S. Lawyed , Mary A. Lawrence
Published: February 2018

This chapter creates the scientometric profile of Vikram Sarabhai Space Centre (VSSC) for the period from 1973 to 2016. The scientific productivity of the scientists is analyzed using scientometric indicators based on the data retrieved from the Scopus database. The analysis revealed that linear growth is prevailing. It also shows that the scientists are actively involved in disseminating their research findings in scholarly journals and G.V. Rao secured first position among the top-ranking authors. The Indian Institute of Science is the leading collaborating institution with VSSC and the United States is topmost collaborating country. Most of the scholarly communications of VSSC are published in the ‘Journal of Sound & Vibration' and a majority of the records are of an article type. Most of the articles are published in the inter-disciplinary subject of Engineering. The study also found that the total number of citations received by the documents published from VSSC are 17395 and out of the 1783 documents published and 1385 documents received citations.
Authorship Pattern and Collaborative Research Productivity of Asian Journal of Dairy and Food Research During the Year 2011 to 2015
Authors: Sivasubramanian Kavitha Elavamalai
Published: February 2018

The chapter brings out the results of a bibliometric analysis of the journal titled Asian Journal of Diary and Food Research for the period from 2011 to 2015. The data was downloaded from the journal's website. This study aims at analyzing the research output performance of co-authorship index and collaborative index. The analysis covers mainly the publication of articles, year-wise distribution of articles, degree of collaboration, institution-wise distribution, authorship pattern, etc. The results show the merits and weakness of the journal which will be helpful for its further development.