bluuebunny/crossref_metadata_2025 huggingface dataset:
KUALITAS PRODUK, RESTO ATMOSPHERE, DAN PERSEPSI HARGA TERHADAP KEPUTUSAN PEMBELIAN
Authors: Kusumawati Octavia Yuli , Hayuningtias Kristina Anindita
Published: August 2022

AbstrakResearch problem is the low purchase decision on Mie Gacoan in Semarang City during the Covid-19 pandemic. The purpose of this study was to determine how much influence product quality, restaurant atmosphere, and price perception had on purchasing decisions at Mie Gacoan in Semarang during the pandemic. This research was conducted on consumers of Mie Gacoan in the city of Semarang. The research technique used is purposive sampling, namely the technique of determining the sample by selecting a sample according to the criteria. The type of data used is primary data. The data collection technique was done by distributing questionnaires through google forms. The results of this study prove that the results of the independent variables of product quality, restaurant atmosphere, and price perception have a partially significant positive effect on the purchasing decision of Mie Gacoan Semarang. The better product quality, restaurant atmosphere, and price perception will influence and improve purchasing decisions. The three independent variables that dominate the most are the independent variable restaurant atmosphere where the value is greater than the other two independent variables.Keywords: Product Quality, Restaurant Atmosphere, Price Perception, Purchase Decision. AbstrakMasalah penelitian ini  adalah rendahnya keputusan pembelian pada Mie Gacoan kota Semarang di masa pandemi Covid-19. Tujuan penelitian ini untuk mengetahui seberapa besar pengaruh kualitas produk, resto atmosphere, dan persepsi harga terhadap keputusan pembelian pada Mie Gacoan kota Semarang di masa pandemi. Penelitian ini dilakukan terhadap konsumen Mie Gacoan di kota Semarang. Teknik penelitian yang digunakan adalah purposive sampling yaitu teknik penetapan sampel dengan cara memilih sampel sesuai dengan kriteria. Jenis data yang digunakan  adalah data primer. Teknik pengambilan data dilakukan dengan penyebaran kuesioner melalui google formulir. Hasil penelitian ini membuktikan bahwa hasil variabel independen kualitas produk, resto atmosphere, dan persepsi harga berpengaruh secara positif signifikan secara parsial terhadap keputusan pembelian Mie Gacoan Semarang. Semakin baik kualitas produk, resto atmosphere, dan persepsi harga akan  mempengaruhi dan meningkatkan keputusan pembelian. Ketiga variabel independen yang paling mendominasi adalah variabel independen resto atmosphere  dimana nilainya lebih besar dibandingkan dengan dua variabel independen lainnya.Kata kunci: Kualitas Produk, Resto Atmosphere, Persepsi Harga, Keputusan Pembelian.
PERBANDINGAN KEPENTINGAN ANTARA DANA DARURAT DAN DANA PENSIUN BESERTA PENGELOLAANNYA
Authors: Shellyna Shellyna , Putri Shieny Tan , Yanty Yanty , Marcelino Marcelino , Akbar Muhammad Azril
Published: August 2022

AbstractLack of society’s awareness related to financial planning will have an impact on financial needs, both short-term and long-term financial goals. In meeting these financial needs, two types of funds that must be known are emergency fund and pension fund. The purpose of this study is to describe the level of importance of emergency fund and pension fund and how to manage them so that people are supposed to be aware and start thinking about their readiness and plan to fulfill the two funds. This study uses descriptive qualitative analysis with a scientific approach based on valid and reliable sources according to the facts on the ground. The results of the research discussion emphasize that the society must first understand their financial needs so that their management can run optimally and sustainably. In an emergency fund, the placement of funds must be in liquid and short-term financial instruments. Whereas in pension fund, the placement of fund can be done in long-term financial instruments as the fund will only be used when old age. Various financial instruments that can be used as placements for emergency and pension funds, namely time deposits, money market mutual funds, gold, stocks and bonds.Keywords: emergency fund; pension fund; management; investment.  AbstrakKurangnya kesadaran masyarakat terkait dengan perencanaan keuangan akan berdampak pada kebutuhan finansial, baik itu tujuan keuangan jangka pendek maupun panjang. Dalam memenuhi kebutuhan finansial tersebut, dua jenis dana yang harus diketahui adalah dana darurat dan dana pensiun. Tujuan dalam penelitian ini adalah untuk mendeskripsikan tingkat kepentingan dana darurat dan dana pensiun serta cara mengelolanya sehingga masyarakat diharapkan dapat sadar dan mulai memikirkan kesiapan serta rancangannya dalam memenuhi kedua dana tersebut. Penelitian ini menggunakan analisis kualitatif deskriptif dengan pendekatan ilmiah yang didasari sumber valid serta reliabel sesuai dengan fakta di lapangan. Hasil pembahasan penelitian menegaskan bahwa masyarakat harus memahami terlebih dahulu kebutuhan finansial mereka supaya pengelolaannya dapat berjalan secara optimal dan berkelanjutan. Pada dana darurat, penempatan dananya harus pada instrumen keuangan yang likuid dan berjangka pendek. Sedangkan pada dana pensiun, penempatan dananya dapat dilakukan pada instrumen keuangan yang bersifat jangka panjang sebagaimana dana hanya akan terpakai ketika masa tua. Berbagai instrumen keuangan yang dapat dijadikan penempatan dana darurat yang bersifat dan pensiun, yaitu deposito, reksadana pasar uang, emas, saham dan obligasi.Kata kunci: dana darurat; dana pensiun; pengelolaan; investasi.
ANALISIS KEMAMPUAN BERPIKIR KREATIF MATEMATIS SISWA PADA MATERI TRIGONOMETRI
Authors: Maryati Iyam , Parani Cindy Elsa
Published: August 2022

This study aims to find out the level of mathematical creative thinking ability of students in solving trigonometry problems. This research approach is a qualitative approach of descriptive type. Data collection techniques are carried out using test methods, interviews and documentation. Data validity test is done by triangulation technique. Data is analyzed using data reduction, data presentation, and inference. The research instrument used is a test of mathematical creative thinking ability. The results of this study, from 12 random high school grade XI students who have taken the test online, as many as 3 people get grades in high categories, as many as 3 people get grades in the moderate category, and as many as 6 people who score in low categories. From the test data and interviews, from the data can be known that the mathematical creative thinking ability of most students of grade XI random high school in Garut district is said to be very low.
KORELASI BELIEFS DENGAN PEDAGOGICAL CONTENT KNOWLEDGE CALON GURU MATEMATIKA
Authors: Sumartini Tina Sri
Published: August 2022

Beliefs and Pedagogical Content Knowledge are important things for prospective mathematics teachers to have. The purpose of this study is to analyze the correlation of beliefs with Pedagogical Content Knowledge of prospective mathematics teachers. The research method used quasi-experimental with purposive sampling technique. The research sample is students majoring in Mathematics Education at Institut Pendidikan Indonesia. Data was collected by giving written tests and questionnaires which were then analyzed using Spearman correlation. The results of the study show that there is a correlation between beliefs and Pedagogical Content Knowledge of prospective mathematics teachers.
PENERAPAN KURVA TRIGONOMETRI UNTUK MOTIF KAIN BATIK - MEDIA PEMBELAJARAN PERSAMAAN TRIGONOMETRI
Authors: Endaryono Endaryono , Azzahra Wirda Hidayah
Published: August 2022

The subject of trigonometric equations is a learning material given to high school students majoring in Mathematics and Natural Sciences and also deepened in student lectures in the fields of science such as mathematics, engineering, informatics and others. The problem discussed in this study is that learning media is still needed to support learning trigonometric equations. The purpose of this research is to create a media for visual simulation of the results of trigonometric equation functions, namely the sine function with various equation models and by modifying the coefficient values in the equation. The results of this simulation are various curve images and are used as a choice of batik motifs. The research methodology uses mathematical modeling with trigonometric equations of sine functions. By changing some of the coefficients in the modification of the sine function, we get an interesting selection of images for batik patterns. The results of the study were in the form of a batik cloth motif design. This research can be used as an interesting learning medium on the subject of trigonometric equations and to addto the richness of various types of batik cloth motifs as an option for lovers of batik cloth art.
ANALISIS OPEN-ENDED PROBLEM SEBAGAI PENILAIAN MATEMATIKA SELAMA PEMBELAJARAN DI ERA PANDEMIC COVID-19
Authors: Solahudin Iman
Published: August 2022

The COVID-19 pandemic has had an impact on Indonesia's education process, which was originally done offline, turned into online, as a result, teachers have difficulty assessing learning outcomes. Open-ended questions are expected to be an alternative in conducting assessments and help analyze students' creativity, reasoning, and mathematical thinking processes. This study aims to analyze Open-Ended in conducting assessments during the Covid-19 Pandemic using a descriptive approach through a case study in a school in Cirebon Regency. The subjects in this study were 2 respondents. Data was collected through a test giving questions about the Open-Ended Problem. Based on the application of two open-ended questions, it was found that all students gave answers correctly, in different ways based on their mathematical knowledge and abilities. Through problem solving by students, creativity, reasoning, and thought processes can be seen from the answers they take. The results of the analysis of all students were able to meet the Open-Ended Problem indicator, although one of the students had a slight deficiency in solving the problem, he did not show his full knowledge, it was seen from the way the explanation of the answer was still not clear. So, presenting open problems is very effective in online learning, students find it difficult to solve problems that have various solutions.
ANALISIS KEMAMPUAN PEMAHAMAN KONSEP MATEMATIS SISWA SMA PADA MATERI TURUNAN FUNGSI ALJABAR
Authors: Rahmawati Nurita Dwi , Roesdiana Lessa
Published: August 2022

Concept understanding is a skill to explore concepts related to mathematics. There are some students who still find it difficult to understand mathematical concepts due to internal and external factors. This study aims to describe the ability to understand mathematical concepts of high school students on the material of Algebraic Function Derivatives. The approach in this study is a qualitative approach using descriptive methods. The research subjects that will be used are 32 students of class XII MIPA. The sample selection used was purposive sampling with random sampling of 3 students for high ability, 3 students for medium ability, and 3 students for low ability. Data collection techniques by providing a mathematical concept understanding test. The data analysis technique used is the Miles and Huberman technique. The indicators on the ability to understand mathematical concepts are 1) linking various concepts, 2) restate the concept, and 3) the ability to classify objects according to certain characteristics according to the concept. In this study, the percentage of students' ability to understand mathematical concepts, including the first and second indicators, was 87.5% and the third indicator was 3.125%. This can guarantee that the first and second indicators show that students can relate linking various concepts and restate the concept of application for the indicators, indicating that there are still many students who are not able the ability to classify objects according to certain characteristics according to the concept.
IZUZEĆE OD JURISDIKCIJE U EUROPSKOM GRAĐANSKOM PROCESNOM PRAVU
Authors: Knol Radoja Katarina
Published: August 2022

The paper analyses the right to be exempt from jurisdiction (immunity) under customary international law and European civil procedural law following the interpretation of the Court of Justice of the European Union. The aim is to research the balance between this right and the right of access to the courts as its potentially restrictive factor in the case law of the Court of Justice of the European Union and to compare it with the case law of the European Court of Human Rights. In deciding the LG and Others v. Rina and Ente Registro Navale as the most important case in this regard, the Court of Justice of the European Union states that the national court before which the issue of exemption from jurisdiction arises, must be persuaded that there will be no violation of the right of access to the courts, if it accepts the immunity objection. In this way, the Court determined the limit of exemption from jurisdiction by allowing the waiver of jurisdiction for reasons of compliance with international legal obligations and noting the need to preserve fundamental rights. However, as to the terms of that limitation, the Court remained vague.
Percutaneous CT-guided retrieval of a retained gallstone to treat a cutaneous fistula following cholecystectomy
Authors: Chivi Simon Peter , Carbonella Gregory
Published: August 2022

This case report describes a technique for the removal of a subcutaneously retained gallstone in a patient who had previously undergone laparoscopic cholecystectomy. The patient’s laparoscopic cholecystectomy was complicated by a perihepatic abscess which was drained percutaneously. The percutaneous abscess drainage was complicated by persistent drainage of tiny stones through the drain tract after the drainage catheter was removed. His computed tomography (CT) revealed a cutaneous fistula between the gallbladder fossa and the right flank with retained gallstones. Despite multiple outpatient general surgery visits, the patient’s wound would not heal, and interventional radiology was consulted for management. Using CT guidance, a retained stone in the right flank was targeted, and a percutaneous approach involving serial dilation and retrieval with a 2.4F × 120 cm Boston Scientific Segura Hemisphere Stone Retrieval Basket (Boston Scientific, Marlborough, MA) through an 18F × 40 cm Cook Check-Flo Performer introducer sheath (Cook, Bloomington, IN) was performed. Similar techniques are used in retrieval of intraluminal objects; however, this is a case in which an object lodged within the soft tissues was retrieved using Seldinger technique.
Zonasi kawasan wisata sejarah Monumen Kresek berbasis CBT (community-based tourism)
Authors: Hartono Yudi , Saputra Andri
Published: August 2022

Desa Kresek Kecamatan Wungu Kabupaten Madiun telah mengembangkan kawasan wisata sejarah Monumen Kresek melalui kelompok sadar wisata (Pokdarwis) â€œMEKARâ€. Kendala yang dihadapi adalah belum adanya kesepakatan tentang zonasi yang berdampak pada kurang tertata dan kurang jelasnya arah pengembangan wisata serta memunculkan masalah lain seperti pedagang dari luar daerah yang secara liar menempati tempat-tempat tertentu untuk membuka lapak dagangannya. Penelitian ini bertujuan untuk mengidentifikasi potensi dan masalah dalam penataan zona wisata sejarah Monumen Kresek dan memetakan zona wisata sejarah Monumen Kresek berbasis CBT (Community-Based Tourism). Penelitian dilakukan dengan metode deskriptif kualitatif. Pengumpulan data dilakukan melalui observasi, wawancara, FGD, dan studi dokumentasi. Penelitian terdiri dari 2 tahapan: 1) Menganalisis potensi dan masalah penataan zona kawasan wisata Monumen Kresek; dan 2) Memetakan zona wisata Monumen Kresek. Hasil penelitian menunjukkan bahwa diperlukan zonasi kawasan wisata sejarah Monumen Kresek, yaitu zona inti, zona penyangga, zona pengembangan, dan zona penunjang. Zonasi kawasan wisata terdiri dari: pertama, area apa yang harus dipertahankan keasliannya; kedua area transisi yang berfungsi edukasi, dan ketiga zona komersial. Ketiga zona tersebut tidak boleh saling tumpang tindih.
Jejak kolonial dalam wawacan regen boncel bupati Caringin karya H.S. ranggawaluja
Authors: Darajat Danan , Koswara Dedi , Suherman Agus
Published: August 2022

Penelitian ini dilatarbelakangi oleh ditemukannya jejak kolonial pada wawacan Regen Boncel bupati Caringin yang merupakan karya sastra Sunda klasik. Dalam wawacan ini diceritakan seorang tokoh bernama Boncel yang asalnya hidup sengsara, tetapi karena dipercaya dan diangkat anak oleh Tuan Asisten Residen, akhirnya dia bisa menjadi seorang bupati di Caringin. Namun, karena durhaka pada ibunya, di akhir kisah hidupnya, Si Boncel menjadi celaka dan sengsara. Secara deksriptif-kualitatif, penelitian ini bertujuan untuk mengetahui dan mendeskripsikan struktur formal, struktur naratif, dan unsur poskolonial (mimikri, hipokritas, hibriditas, dan ambivalensi) yang terdapat dalam wawacan Regen Boncel Bupati Caringin karya H.S. Ranggawaluja. Hasilnya dapat disimpulkan bahwa struktur yang terdapat dalam wawacan tersebut sudah lengkap, yang meliputi struktur formal (guru lagu dan guru wilangan, watak pupuh, dan sasmita pupuh), struktur naratif (alur, motif cerita, pelaku, latar, dan tema). Selanjutnya, dalam wawacan ini juga ditemukan adanya unsur poskolonial yang meliputi mimikri, hipokritas, hibriditas, dan ambivalensi.
KEGAGALAN SISTEM EKONOMI SOSIALIS
Authors: Anggraeni Rahma Dewi , Rahmaddina Rizqa , Aisyah Rohmadatul
Published: August 2022

Studi ini akan berfokus pada pembahasan mengenai kegagalan sistem ekonomi sosialis metode yang digunakan dalam penelitian kualitataif dengan pendekatan deskriptif. Sistem Ekonomi Sosialis yang tercipta karena adanya pemikiran dari beberapa tokoh yang tidak terima mengenai adanya dampak dari ekonomi kapitalis yang dinilai sangat merugikan rakyat dengan ekonomi menengah kebawah. Munculnya sistem ekonomi sosialis yang dibawa oleh Karl Marx membawa harapan besar bagi rakyat yang terdampak pada zaman itu akibat ekonomi kapitalis. Namun, harapan besar itu dianggap tidak sejalan dengan hasil yang ada. Sistem Ekonomi Sosialis mengalami kegagalan dalam penerapannya. Ditandai dengan runtuhnya Uni Soviet sebagai negara yang memakai sistem ekonomi ini, dengan faktor yang mendasari runtuhnya adalah karena kegagalan ekonomi akibat pengimplementasian sistem ekonomi yang kurang tepat dan maksimal. Dengan runtuhnya Uni Soviet, maka sistem ekonomi ini dianggap pula berakhir dan mengalami kegagalan.
UPAYA MENINGKATKAN PRESTASI BELAJAR EKONOMI PADA KOMPETENSI DASAR KERJA SAMA EKONOMI INTERNASIONAL DENGAN MODEL PEMBELAJARAN SNOWBALL THROWING SISWA KELAS XI IPS 2 SMA NEGERI 5 MADIUN KOTA MADIUN TAHUN PELAJARAN 2018/2019
Authors: Setiabudi KW
Published: August 2022

Penelitian tindakan kelas ini bertujuan untuk: (a) mengetahui peningkatan mutu belajar siswa setelah menerapkan model pembelajaran Snowball Throwing Kelas XI IPS 2 2018/2019 (b) Setelah menerapkan model pembelajaran Snowball Throwing, peneliti ingin mengetahui bagaimana pengaruh kemauan belajar siswa. Penelitian ini menggunakan tiga putaran penelitian tindakan. Setiap putaran terdiri dari empat fase: desain, aktivitas dan observasi, pertimbangan dan revisi. Subjek dari penelitian yaitu siswa kelas XI IPS 2. Data yang diperoleh merupakan hasil tes formatif berupa lembar observasi untuk kegiatan pendidikan dan pembelajaran. Hasil analisis menunjukkan bahwa kualitas belajar siswa pada Siklus I (38%), Siklus II (68%) dan Siklus III (86%) meningkat. Kesimpulan dari survei ini adalah penerapan metode pembelajaran snowball throw memberikan dampak positif yaitu dapat memotivasi siswa untuk belajar, dibuktikan dengan wawancara dengan beberapa siswa. teknik Snowball Throwing memotivasi siswa untuk belajar. Model pembelajaran ini dapat dijadikan sebagai alternatif pembelajaran ekonomi.
MEMPERSIAPKAN ENTREPRENEUR MUDA SEJAK DINI DI YAYASAN PONDOK PESANTREN AZ-ZAHRA (SMP TULUNG AGUNG)
Authors: Rislawati Nita , Ananda Rolly Rezki , Syamat Rizky Kurniawan , Adhadianawaty S.A.S Noor , Fitriansyah Fitriansyah
Published: August 2022

Abstract. The importance of the role of youth to face the future, so they must be equipped and prepared with education about entrepreneurship. The entrepreneurial spirit (entrepreneur) at the basic education level is to develop independent, creative, leadership and hard work traits. To improve and prepare for this, socialization or counseling was carried out at the Az-Zahra Islamic Boarding School Foundation (SMP Tulung Agung) on Jl. Axis Samarinda -Tenggarong Gg. Langsat RT. 002 Jembayan Village, Jembayan, Loa Kulu, Kutai Kartanegara. The socialization will on 28 March 2022. The purpose of this socialization is to provide knowledge about entrepreneurship and build an entrepreneurial spirit. The method used in this activity is to provide education in the form of counseling about entrepreneurship, discussions and questions and answers. The results of this activity obtained from student response data state that students have known about entrepreneurship more broadly and can instill entrepreneurial spirits and interest in entrepreneurs.

Abstrak. Pentingnya peranan pelajar untuk menghadapi masa depan, sehingga harus dibekali dan dipersiapkan edukasi mengenai kewirausahaan. Jiwa kewirausahaan (entrepreneur) pada jenjang pendidikan dasar adalah dengan mengembangkan sifat mandiri, kreatif, kepemimpinan dan kerja keras. Untuk meningkatkan dan mempersiapakan hal tersebut dilakukan sosialisasi atau penyuluhan di Yayasan Pondok Pesantren Az-Zahra (SMP Tulung Agung) di Jl. Poros Samarinda -Tenggarong Gg. Langsat RT. 002 Desa Jembayan, Jembayan, Loa Kulu, Kutai Kartanegara. Sosialisasi dilaksanakan pada tanggal 28 Maret 2022. Tujuan dari sosialisasi ini adalah memberikan pengetahuan mengenai kewirausahaan dan membangun jiwa entrepreneur. Metode yang digunakan pada kegiatan ini ialah dengan memberikan edukasi berupa penyuluhan mengenai kewirausahaan, diskusi serta tanya jawab. Hasil dari kegiatan ini diperoleh dari data respon pelajar menyatakan bahwa para pelajar telah mengetahui tentang entrepreneur lebih luas lagi dan dapat menanamkan jiwa-jiwa entrepreneur serta ketertarikan terhadap entrepreneur.
PELATIHAN MEMBANGUN MINDSET BISNIS SYARIAH PADA IBU RUMAH TANGGA
Authors: Khalifaturofi'ah Sholikha Oktavi , Africa Laely Aghe , Nasution Zubaidah
Published: August 2022

Abstract. Being a housewife is a noble position because of her role in taking care of the household and children. However, now there is a distortion. Housewives who are judged to just stay at home, it turns out that they also fill their activities with business. The purpose of this training is to build a sharia business mindset for Muslim women who are married. Women who are married, have children, always struggle with household activities and take care of their husbands and children. Therefore, we need a training that can improve the capability of housewives who are already married so that they can be self-actualized, independent, and have their own income. The method of implementation is preparatory training to start a business based on sharia economic principles, and is equipped with material on the history of the Prophet and why as a housewife should be able to work. The result of this activity is that partners are motivated to be able to do business and increase partner knowledge to build businesses based on sharia principles.

 

Abstrak. Menjadi seorang ibu rumah tangga adalah posisi yang mulia karena perannya dalam mengurus rumah tangga dan anak. Akan tetapi, saat ini mulai terjadi distorsi. Ibu rumah tangga yang dinilai hanya diam saja di rumah, ternyata juga mengisi kegiatan dengan berbisnis. Tujuan dari pelatihan ini adalah untuk membangun mindset bisnis syariah pada perempuan muslim yang sudah berkeluarga. Perempuan yang sudah menikah, mempunyai anak, selalu berkutat dengan kegiatan rumah tangga dan mengurus suami dan anak. Oleh karena itu, diperlukan suatu pelatihan yang dapat meningkatkan kapabilitas ibu rumah tangga yang sudah berkeluarga supaya dapat mengaktualisasi diri, mandiri, dan mempunyai penghasilan sendiri. Metode pelaksanaannya adalah pelatihan persiapan untuk memulai usaha berdasarkan prinsip ekonomi syariah, dan dilengkapi dengan materi sejarah Rasulullah dan mengapa sebagai seorang ibu rumah tangga harus dapat berkarya. Hasil dari kegiatan ini adalah mitra termotivasi untuk dapat berbisnis dan menambah pengetahuan mitra untuk membangun bisnis berdasarkan prinsip syariah.

 

 
Angiotensin-(1-7): A novel therapeutic target for preventing cardiovascular disease
Authors: Gupta Jeetendra Kumar , Singh Krishanveer , Singh Kuldeep
Published: August 2022

Angiotensin-(1-7) is a vasoactive heptapeptide of renin-angiotensin system which is usually produced by angiotensin converting enzyme 2 and exhibits activity through activation of Mitochondrial assembly (Mas) receptor. In present scenario, the Ang-(1-7)/ACE2/Mas axis has tendency to counterbalance many vasoconstrictor biomolecules such as classical renin angiotensin system that includes ACE, ANG, renin, AT1 and AT2 receptors. Ang (1-7) is a vasodilator substance that shows significant roles in cardiovascular system. Because of the protective roles of Ang-(1-7) in cardiomyocytes and endothelial tissues, it is also known to evoke anti- arrhythmogenic effects as well as endogenous inducer for the release of vasodilators like nitric oxide and prostanoids. Moreover, the heptapeptide Ang-(1-7) is also being explored against organ failure, renal diseases, preeclampsia and even against carcinoma. This review circumscribes many pharmacological potentials of Ang-(1-7) against various physiological conditions.
Selective Reductive Cleavage of the Threonine 2 Peptide Bond of Penta-N-Boc-Polymyxin B with Sodium Borohydride
Authors: Weinstein Jay , Afonso Adriano
Published: August 2022

Sodium borohydride surprisingly cleaves the Threonine2 (Thr2) peptide bond in N-protected Polymyxin B. Occurring at 20 ºC, the mild reductive cleavage is novel; and it facilitates the synthesis of PMB-derived antibiotics. The reaction fails when both Threonine2,10 hydroxyls are protected. The reaction can be performed on all therapeutic peptides containing Threonine.
Site-selective Electrochemical Oxidation of Glucosides
Authors: Kidonakis Marios , Villotet Augustin , Witte Martin , Beil Sebastian , Minnaard Adriaan
Published: August 2022

Quinuclidine-mediated electrochemical oxidation of glycopyranosides provides C3-ketosaccharides with excellent selectivity. The method is a versatile alternative to Pd-catalyzed oxidation, and to photochemical oxidation, and is complementary to the TEMPO-mediated C6-selective oxidation. Contrary to the electrochemical oxidation of methylene and methine groups, the reaction does not require oxygen.
Synthesis and Biological Evaluation of C(13)/C(13’)-Bis-Desmethyl-Disorazole Z
Authors: Bold Christian Paul , Lucena-Agell Daniel , Ángela Oliva María , Díaz José Fernando , Altmann Karl-Heinz
Published: August 2022

We describe the total synthesis of the macrodiolide C(13)/C(13')-bis-desmethyl-disorazole Z via double inter-/intramolecular Stille cross-coupling of a monomeric vinyl stannane/vinyl iodide precursor to achieve macrocycle formation. The key step in the synthesis of this precursor was a stereoselective aldol reaction of a formal Evans acetate aldol product with crotonaldehyde. As demonstrated by X-ray crystallography, the binding mode of C(13)/C(13')-bis-desmethyl-disorazole Z to tubulin is virtually identical with that of the natural product disorazole Z (1). Likewise, C(13)/C(13')-bis-desmethyl-disorazole Z inhibits tubulin polymerization with the same potency as disorazole Z and it appears to be a more potent cell growth inhibitor.
IMPORTANCIA DE DIENTES DECIDUOS EN LA ERUPCIÓN DE DIENTES PERMANENTES: PERCEPCIÓN DE LOS PADRES DE FAMILIA EN UN CENTRO POBLADO DE LAMBAYEQUE
Authors: Aquino Sánchez Brenda Ivonne , Ríos Vera Oycer Luis , Arrunátegui Huamán Betsy Pamela
Published: August 2022

Las investigaciones nos muestran que hoy en día, las familias desconocen la importancia de la dentición decidua de sus hijos, señalando que existe un alto porcentaje de preescolares que sufren la pérdida de piezas dentales por distintas causas, trayendo consigo problemas odontológicos de distinta índole, es por ello, que esta investigación propuso como objetivo evaluar la percepción que tienen los padres de familia con respecto a la importancia de dentición decidua en la erupción de dentición permanente, la investigación fue de tipo descriptivo de corte transversal, utilizando un muestreo no probabilístico por conveniencia, en donde aplicando criterios de inclusión y exclusión, la muestra estuvo compuesta por 17 padres de familia de una institución educativa inicial del centro poblado Tablazos del distrito de Chongoyape, en la provincia de ChiclayoLambayeque; a quienes se les aplicó un cuestionario estructurado de 25 ítems, encontrando como resultados que el 52.9% de los padres de familia de la institución educativa tienen edades comprendidas entre 20 a 30 años, el 70.6% son procedentes de la Costa, el 47.1% de ellos manifestó tener estudios superiores y un 58.8% mencionan ser trabajadores dependientes. Concluyendo que, en relación al nivel de conocimiento de la importancia de los dientes deciduos para la adecuada erupción de dientes permanentes, el 53% de los padres posee un nivel medio de conocimiento, el 29% un nivel bajo, y sólo un 18% de los padres de familia demostraron tener un nivel de conocimientos alto.
RELACIONES INTERPERSONALES ODONTÓLOGO-PACIENTE EN LA CONSULTA ODONTOLÓGICA DESDE UNA PERSPECTIVA PROFESIONAL
Authors: Poclin Quispe Kevin José , Coronel Zubiat Franz Tito
Published: August 2022

Objetivo: Determinar el nivel de percepción de la relación interpersonal cirujano dentista – pacientes en la región Amazonas 2020.

Materiales y Métodos: El estudio fue descriptivo, prospectivo de corte transversal, con un enfoque cuantitativo. Se evaluó a 75 cirujanos dentistas.

Resultados: En la presente investigación, se apreció que las relaciones interpersonales de los cirujanos dentistas con sus pacientes fueron buenas, con un 89.3%; y de acuerdo a las dimensiones, se obtuvo que el nivel de comunicación presento un 90.1%, seguido del trato con 89.4 y la actitud 88.5% todos con un buen nivel.

Conclusión: El nivel de percepción fue buena respecto a la relación interpersonal de los cirujanos dentistas con sus pacientes de la Región Amazonas 2020.
Diagnostic Accuracy of Physical Examination Tests for Suspected Acute Anterior Cruciate Ligament Injury: A Systematic Review and Meta-Analysis
Authors: Tanaka Shigeharu , Inoue Yu , Masuda Yuki , Tian Hui , Jung Hungu , Tanaka Ryo
Published: August 2022

Background

Many tests are used to examine the knee when anterior cruciate ligament (ACL) injury is suspected. However, evidence of diagnostic accuracy in the Lachman, anterior drawer, pivot shift, and lever sign tests is limited.

Purpose

The purpose of this study was to perform a systematic review and meta-analysis of original research studies that assessed the diagnostic accuracy of four physical examination tests for ACL injury acutely after an injury.

Study design

Systematic review and meta-analysis.

Methods

A literature search was conducted in the PubMed, MEDLINE, CINAHL, Web of Science, and Ichushi databases. Original articles with prospective cohort and cross-sectional studies in English and Japanese were included. The searched words were “anterior cruciate ligament”, “injury”,” rupture”,” tear”, “lachman test”, “pivot shift test”, “anterior drawer test”, “lever sign test”. The methodological quality of the diagnostic studies was evaluated using QUADAS-2. Summary sensitivity, specificity, likelihood ratio (LR)+, and LR– with 95% confidence intervals were calculated.

Results

Eight studies were included in this review. The methodological quality of the included studies was mostly favorable. For the domain of flow and timing in the QUADAS-2, three studies did not assess the timing between the reference and index tests. The pooled sensitivities were 0.79, 0.78, 0.55, and 0.82 in the Lachman, anterior drawer, pivot shift, and lever sign tests, respectively, and the pooled specificities were 0.91, 0.91, 0.96, and 0.88, respectively. The lever sign test had the lowest LR− (0.21) and the pivot shift test had the highest LR+ (11.60). The area under the curve for the four physical examinations was > 0.70.

Conclusion

The lever sign and pivot shift tests are useful for diagnosing ACL injuries in an acute setting.

Level of Evidence

Level 2
Effect of Concussion on Reaction Time and Neurocognitive Factors: Implications for Subsequent Lower Extremity Injury
Authors: Ray Tyler , Fleming Daniel , Le Daniel , Faherty Mallory , Killelea Carolyn , Bytomski Jeffrey , Ray Tracy , Lemak Larry , Martinez Corina , Bergeron Michael F. , Sell Timothy
Published: August 2022

Background

Recent evidence has demonstrated that athletes are at greater risk for a lower extremity injury following a return-to-sport (RTS) after sport-related concussion (SRC). The reason for this is not completely clear, but it has been hypothesized that persistent deficits in neurocognitive factors may be a contributing factor.

Hypothesis/Purpose

This study assessed simple reaction time, processing speed, attention, and concentration in a group of athletes, post-concussion upon clearance for RTS for potential deficits that may result in slower reaction time, processing speed, attention, and concentration. The researchers hypothesized that the concussion group would demonstrate worse scores on both assessments compared to a sex-, age-, and sport-matched cohort.

Study Design

Case-controlled study

Methods

Twelve participants who had suffered a SRC and eight healthy individuals who were matched to the concussed group by age, sex, and sport were evaluated. Those with a concussion had been cleared for RTS by a licensed healthcare provider. Each participant underwent neurocognitive tests that included a simple reaction time test (SRT) and the King-Devick Test (K-D). Independent t-tests were performed to compare the groups with significance set a priori at p<0.05.

Results

There was a significant difference (p =0.024) between groups for SRT with the concussed group demonstrating a better SRT than the control group. There were no significant differences (p =0.939) between the groups for the K-D.

Conclusion

With no significant differences between groups in the K-D assessment and, surprisingly, the concussed group having a better SRT compared to the healthy group, our hypothesis was not supported.

Clinical Relevance

These specific measures, compounded with extensive post-concussion time lapse until RTS clearance, may have limited capacity in revealing potential persistent deficits in relevant neurocognitive characteristics.

Level of Evidence

Level of Evidence 3
Delayed Recovery after Nonoperative Treatment of an Avulsion Fracture of the Ischial Tuberosity in an Adolescent Gymnast with a History of Growth Hormone Deficiency: A Case Report
Authors: Meshram Prashant , Vadhera Amar S. , Sachdev Rahul , McFarland Edward G.
Published: August 2022

Introduction

Avulsion fracture of the ischial tuberosity is uncommon. Patients typically present with symptoms consistent with hamstring strain. The purpose of this case report is to describe an avulsion fracture of the ischial tuberosity and subsequent recovery in an athlete with an endocrine disorder.

Case Description

A 15-year-old United States of America Gymnastics level 9 gymnast presented with right hamstring pain after regular practice. She had been diagnosed with isolated growth hormone deficiency at age 4 and was treated with growth hormone replacement therapy until age 14. Six months before presentation, she experienced the insidious onset of dull, aching pain in her right hamstring, near the junction of the thigh and buttocks, that was believed to be the result of a chronic hamstring strain. The pain increased gradually over a year and was relieved with rest, massage, and dry needling. Two days before presentation, she felt a “snap” and pain while performing a switch leap during regular practice. She had sharp localized pain in the proximal hamstring with walking and sitting. She was diagnosed with a minimally displaced avulsion fracture of the ischial tuberosity.

Outcome

With nonoperative treatment, the fracture healed at three months, which is longer than the expected six weeks. Although return to sports is expected three months after this injury, it did not occur until six months in this patient. She was unable to participate in competitive level 9 gymnastics until 12 months after injury.

Discussion

This case highlights that delayed recovery can occur after avulsion fracture of the ischial tuberosity in adolescent athletes with a history of growth hormone deficiency and treatment using growth hormone.

Level of Evidence

5
Implementation of machine learning techniques for depression in text messages: a survey
Authors: Divya Dewangan , Smita Selot , Sreejit Panicker
Published: August 2022

Depression is a disease or problem associated with high levels of stress seen in humans. It is uncomfortable in talking to parents, psychologists, and healthcare professionals in general. So a virtual platform is much more suitable for sharing your emotions, for example, a chatbot that provides the user with a comfort zone, acting as a friend or well-wisher. Extracting and identifying emotions from text messages to detect depressive mood is a challenging task because it involves removing natural language ambiguities. Over the past decade, researchers have proposed various state-ofthe- art methods for detecting depressive moods in text. This paper aims to analyze such methods and present a comparison based on detection accuracy. The virtual platform provides an end-user interface for communication. The system understands the meaning and context of a sentence using Natural Language Processing (NLP), word embedding, and machine learning techniques. NLP does the preprocessing and extracts the mental health-related keywords. Word embedding converts the extracted keywords into embedding vectors that can be understood by Machine learning algorithms, it can also analyze and extract users' feelings by examining and calculating levels of depression and classifying the user as depressed or not. This paper showed that the support vector machine is the preferred algorithm over other machine learning algorithms and provides higher accuracy.
Our Common Ground: Finding Our Imagination in the Garden
Authors:   , Gilbert Anna
Published: August 2022

Recent rhetoric in landscape architecture has illuminated the complex nature and broad scope of the discipline in such a way that augments instrumental, solutionist, and measurable modalities of practice over the imaginative.

As such, the significance of aesthetics and any criticality of nature (i.e. the gardener’s realm) are often ignored and/or dismissed. In fact, many landscape architects are ill-equipped to design gardens that move us, and some practitioners may even demarcate their practice by excluding the garden completely.

This practice-led research suggests that if this is so, then the designed ‘products’ of landscape architecture risk presenting as reductive, commodified, privatised, and devoid of imaginative quality or repose. The research addresses these concerns by engaging landscape architecture with the realm of the garden and acts of gardening. To this end, a purpose fit and performative methodology is developed to investigate garden-essence, whatever that is shown to mean. Embedded in this approach is a broader aspiration to foreground the conception of public life that posits garden presence as an essential component of our collective imagination. Consequently this research finds a way to approach and design landscape in kind with those often intangible aspects of gardening which afford delight, wonder, and reverence for the natural world.
Transactional Leadership in the Public Sector: Integrating Public Values
Authors:   , Nguyen Trang Thu
Published: August 2022

Agreement exists that leadership studies should give increased attention to the application of generic leadership in specific contexts. In the public sector, a specific need exists to examine the effect of public values on the content and effectiveness of leadership. This study adds to the public administration literature by, principally, developing a transactional leadership (TL) substyle that incorporates public values (PV). This thesis calls this substyle “Public Values-focused Transactional Leadership” (PVTL).

 Three main study questions are addressed: (1) What is the impact of Transactional Leadership on the Organisational Commitment (OC) of public employees? (2) What is the impact of Public Values on Organisational Commitment? (3) What is the impact of Public Values-focused Transactional Leadership on the Organisational Commitment?

 This study uses a multiphase mixed-method design and data gathered from 25 interviews and a dyadic survey of 499 employees and 78 supervisors across 27 public agencies in Vietnam. Empirical results show positive, direct impacts of TL, PV and PVTL on OC. It also finds indirect impacts of PVTL on OC through psychological contracts, and a mediation effect of a participatory style on the relationship between PVTL and OC. Hence, support is provided for the relationships of the above study questions. PVTL is discussed as a new, useful construct for public sector leadership studies and as holding promise for improving public sector management.
Embodied Carbon Footprint in Medium Density Housing Design
Authors:   , Fleming Madison
Published: August 2022

The built environment is responsible for approximately 20% of New Zealand’s carbon footprint. Sustainable design strategies may potentially present an opportunity to reduce the environmental impacts of buildings. To this end, this thesis will focus on the effect design decisions have on that use of finite resources/ building material in medium density housing (MDH).

As a response to New Zealand’s housing crisis and affordability, there is a changing perspective around MDH. The demand for MDH in New Zealand since 2017 was projected to increase 6% per year (BRANZ, 2017, p. 1). Of the projected MDH, approximately 51% of the dwellings are to be built in the Auckland region (Page, 2017, p. 14). This thesis posits and tests sustainable design strategies of MDH dwellings that do not compromise aesthetic qualities for functionality. Design-led research will identify the relationship between design and carbon, providing conclusions on how MDH can be designed to have a lower impact on the environment.
Doing Guerrilla Architecture (A Shift in Practice)
Authors:   , Anderson Carolina
Published: August 2022

This thesis seeks to position ‘guerrilla architecture’ as an alternative approach to conventional architectural practice, in an attempt to shift architecture to be more inclusive and collaborative, less exclusive and prescribed. It looks to build upon the understanding of key questions: ‘how to be a guerrilla architect? ’and ‘how to do guerrilla architecture?’. More specifically, this research project seeks to understand how guerrilla tactics such as temporary architecture, can be used to transform existing urban spaces into true public spaces which invite collaboration and sharing, using the idea of ‘commoning.’ Employing an auto-ethnographic form of qualitative methodology, this research aims to develop a more democratic architectural process. Using the city of Wellington as the testing ground, selected urban spaces are activated by employing guerilla tactics through a series of experiments. Wellington was selected as it lacks well-utilised shared spaces where people can socialise, connect and engage through shaping their environment.

The guerrilla strategies use urban commoning, an ever-developing collaborative process of social practices, to temporarily transform underutilised public spaces in Wellington.

These social practices, such as dancing, art and commensality (the act of eating together), were used as activators to empower people to revitalise public space in a collaborative and inclusive way. The guerrilla method included D-I-Y performance interventions to construct temporary situations. Each experiment was recorded through observations, videos, photographs, drawing, reflexive learning and doing, and conversations with participants and collaborators.

This project draws upon contemporary discourse questioning the role of the architect, and architecture’s engagement and relationship with activism and social justice. The research aims to add to the growing body of knowledge which shifts the practice of the architect and architecture from the traditional and conventional ‘starchitects’ and ‘starchitecture’, which can be seen at one extreme end of the spectrum, to a more collective, democratic and feminist approach. Faced with ever increasing inequality, privatization of urban space, and environmental degradation, reinventing the role of the architect is critical to be able to respond to these important challenges.
Adoption of Phīn tuning on Classical Guitar
Authors:   , Sobhanasiri Sirisan
Published: August 2022

Traditional Thai music has received little attention in academic study. Additionally, the repertoire for classical guitar is not as wide as other Western classical instruments. Therefore, this thesis has two main objectives. The first is to establish a database on traditional Isan (north-eastern Thailand) music, sourced from Thai works of literature and personal interviews. The establishment of this database was necessary to enable a thorough exploration of Thai Isan music. This, subsequently, helps explain phīn (Thai mandolin) tuning. This phīn tuning can be adopted to classic guitar, which is an effective way to apply the characteristics of traditional instruments to a classical western instrument. The second objective is to expand the repertoire on the phīn tuned classical guitar by collaborating with three composers; one guitarist and two non-guitarists. This thesis also explores collaboration processes and the idea behind each collaborative piece. Although it is challenging for non-guitarist composers to compose for the guitar, collaboration with guitarists will foster non-guitarist composers to contribute to a guitar repertoire. The results of the project are four new guitar pieces on the phīn tuned classical guitar and new genres of classical guitar repertoire, which integrates Asian and Western classical music.
Imprimōtype: A new experience of analogue photography through tactility, tangibility and sacrifice
Authors:   , Kong Sarah Rhonda
Published: August 2022

 This thesis began as a critical response to digital photography. It  takes an in depth look at the transition of photography from analogue to  digital, and the impact of this transition on the culture of  photography. This design-led research features a series of experiments  that cross and merge the boundaries between digital and analogue  photographic processes to offer an alternate experience of photography  by tangibly re-evaluating the relationship between the camera and the  photograph. Finally, this thesis leads to the creation of the  ‘Imprimōtype,’ (Literally ‘print type’) a sacrificial camera that  provides an alternate experience of photography rich in physical  tangibility, tactility, anticipation, reward and emotional connection to  the resulting photograph that comes only with temporal investment and  connection in the photographic process. 