bluuebunny/crossref_metadata_2025 huggingface dataset:
Trajectories of posttraumatic growth and posttraumatic depreciation: A one-year prospective study among people living with HIV
Authors: Pięta Małgorzata , Rzeszutek Marcin
Published: September 2022

Objective

Posttraumatic growth (PTG) and posttraumatic depreciation (PTD) are considered two sides of growth after trauma. Nevertheless, previous studies pointed out that in trauma living with a life-threatening illness, they may be experienced as two independently and share distinct predictors. In our study we aimed to find the different trajectories of PTG and PTD among a sample of people living with HIV (PLWH) and to investigate its predictors out of psychological resilience, and gain and loss of resources from the conservation of resources theory (COR).

Methods

We designed a longitudinal study that consisted of three measurements at 6-month intervals, and we recruited, respectively, 87, 85 and 71 PLWH. Each time participants filled out the following questionnaires: the expanded version of the PTG and PTD Inventory (PTGDI-X), the Brief Resilience Scale (BRS), the Conservation of Resources Evaluation (COR-E), and a survey on sociodemographic and medical data.

Results

We observed two separate trajectories of PTG and PTD within participants and found that each of the trajectories were related to different predictors from the studied variables. More specifically, we found a positive relationship between resilience and a descending PTD trajectory that stabilized over time. Gain of resources generally predicted a PTG trajectory, while loss of resources predicted the dynamics of PTD.

Conclusions

Including two parallel constructs, i.e., PTG and PTD, confirmed the independence of their mechanisms in growth processes among PLWH. The initial insight concerning the role of resilience and resources in PTG/PTD processes may inspire more effective planning for psychological help for PLWH, and it may stimulate studies on growth after trauma to further examine the two sides of this phenomenon.
Prevalence, causes, and factors associated with obstructed labour among mothers who gave birth at public health facilities in Mojo Town, Central Ethiopia, 2019: A cross-sectional study
Authors: Girma Tarekegn , Gezimu Wubishet , Demeke Ababo
Published: September 2022

Background

Obstructed labour is a type of abnormal labour that is one of the causes of obstetric complications such as maternal and fetal mortality and morbidity. Early detection is the key to reducing complications.

Objective

This study aimed to assess the prevalence, causes, and factors associated with obstructed labor among mothers who gave birth at public health facilities in Mojo Town, Central Ethiopia.

Methods

An institution-based cross-sectional study was conducted from November 10 to December 30, 2019 among 318 women who gave birth at public health facilities in Mojo Town. Face-to-face interviews and participants’ medical record reviews were utilized to gather data. The collected data were checked, coded, and entered into EpiData version 3.1 and then exported to SPSS version 23 for analysis. A binary logistic regression model was used to test the association between the dependent and independent variables. In bivariate analysis, all variables with a p-value less than 0.25 were included in multivariate analysis. Finally, a significant statistical association was declared at a p-value less than 0.05.

Results

The prevalence of obstructed labour in this study was 51 (16%), and cephalo-pelvic disproportion (66%), mal-presentation (22%), and mal-position (12%) were reported as causes of obstructed labour. Primgravidity (AOR = 7.74: 95%CI = 2.13, 18.2) and a one-time antenatal care follow-up (AOR = 9.50: 95%CI: 1.91, 33.07) were found to be associated factors with obstructed labour, while labour duration of 12–24 hours (AOR = 0.20: 95%CI = 0.17, 0.87) was identified as a factor decreasing the risk of obstructed labour.

Conclusion

The prevalence of obstructed labour in this study was higher than in the majority of previous similar local and global studies. In this study setting, cephalo-pelvic disproportion, mal-presentation, and mal-position were found to be the causes of obstetric labour. Additionally, factors such as gravidity, frequency of antenatal follow-up, and duration of labour were significantly associated with obstructed labour. Therefore, the concerned entities need to work to curb young age pregnancy as well as to strengthen counselling mothers on the importance of subsequent antenatal-follows in the prevention of obstructed labour.
Languaging designing
Authors: Lockheart Julia
Published: September 2022

This article looks at how language can be used in metadesign approaches, processes and tools to foster empathic and considerate design teams. Metadesign places a strong emphasis on language as a tool for designing and communicating. It draws upon my doctoral thesis that considers a range of approaches to co-writing, and our forthcoming book, Metadesigning Designing in the Anthropocene, which offers a range of perspectives regarding what metadesign teams can and should do to foster change now we have reached this existentially precipitous point in human history. The slow languaging approaches, processes and tools described here are used within my workshops with interdisciplinary teams.
Populism, the Pandemic and the Media-Journalism in the Age of Covid, Trump, Brexit and Johnson, John Mair, Tor Clark, Neil Fowler, Raymond Snoddy and Richard Tait (eds) (2021)
Authors: Browning Gary
Published: September 2022

Review of: Populism, the Pandemic and the Media-Journalism in the Age of Covid, Trump, Brexit and Johnson, John Mair, Tor Clark, Neil Fowler, Raymond Snoddy and Richard Tait (eds) (2021)

Bury St. Edmunds: Abramis Academic Publishing, 330 pp.,

ISBN 978-1-84549-785-9, p/bk, £19.95
EPIDEMIOLOGY OF AIDS IN A NORTHEASTERN BRAZILIAN STATE
Authors: Maranhão Thatiana Araujo , Ribeiro Leonardo Miranda , Sousa George Jó Bezerra , Matos Mariana Araujo , Silva Taynara Lais , Da Silva Isaac Gonçalves , Pereira Maria Lúcia Duarte
Published: September 2022

Objective: to identify high-risk clusters to AIDS and describe the epidemiologic profile of the disease in the municipalities of the State of Piauí, Brazil, from 2007 to 2015. Methods: This ecological study included 2.908 cases notified by the Brazilian System of Notifiable Diseases. Univariate and bivariate analyses were performed and the spatial scan statistic was used to evaluate the formation of purely AIDS clusters, with a significance of 5%. Results: Significant associations were observed between sexual orientation and sex and age (p<0.0001). The most probable cluster, with a relative risk (RR) of 5.05 (p <0.0001), covered six cities, including the capital of the state, Teresina. The BR-343 highway cuts through five cities in the Center-north mesoregion of state, with RRs to AIDS above the state average. Conclusions: Preventive intervention strategies are needed for young people, homosexual/bisexual men as well as in cities with high RR to AIDS that are transected by highways.
Exégesis científica y teología dogmática
Authors: García Fernández Marta
Published: September 2022

El ensayo ilustra desafíos comunes y sendas de reencuentro entre exégesis científica y teología dogmática. Para ello parte de la separación que se produjo en el siglo XVIII entre sendas disciplinas. La primera parte se concentra sobre el quehacer teológico y analiza particularmente la necesaria integración entre la fe y el método. La hermenéutica de Gadamer y Ricoeur orienta y articula los contenidos de esta sección en la que se proponen espacios de diálogo y reflexión entre exégesis científica y teología dogmática. Mientras la primera parte se escora hacia la praxis de la teología, la segunda aborda aspectos más teóricos. En concreto, sugiere una clarificación de conceptos con el fin de acabar con las dicotomías presentes en parte debidas a la naturaleza divino-humana de la Escritura.
Los retos de las ciencias a la concepción cristiana de lo humano
Authors: Beorlegui Rodríguez Carlos
Published: September 2022

La idea que los humanos tenemos de nosotros mismos ha ido cambiando de forma continua, debido a la acumulación de conocimientos que nos aportan las diferentes áreas del saber, sobre todo las ciencias. Frente a quienes defienden que los avances científicos están suponiendo un desmoronamiento del modelo antropológico cristiano, este trabajo defiende que los enfrentamientos y discrepancias no se dan tanto entre las ciencias y la teología cristiana, sino entre interpretaciones filosóficas reduccionistas de los datos científicos y las afirmaciones centrales del ideal cristiano del ser humano. Así, más que darse un conflicto irresoluble entre ciencia y fe, entre ellas se da un diálogo fructífero, que las purifica y enriquece.
El nihilismo de la secularización posmoderna
Authors: Chillón José Manuel
Published: September 2022

En este trabajo intentaré ofrecer una visión de la situación del cristianismo en nuestras sociedades posmodernas tratando de averiguar si todavía hoy podemos seguir utilizando la categoría secularización, propia del pensamiento ilustrado. Se sostiene aquí que, sin embargo, la secularización debe entenderse, en nuestro contexto posmoderno, como expresión del nihilismo que, más que entrar en liza con lo religioso, llega a vaciar su contenido de verdad. Se trata de diferenciar la secularización del cristianismo de la secularización en el cristianismo. Esta última es la secularización que, comprendida desde la matriz del nihilismo, se expresa en el mantenimiento de las formas, de las estructuras y de los estilos, a costa de asumir la nula relevancia pública de lo religioso en lo que a pretensiones de verdad se refiere. Con todo, el nihilismo conecta con lo que aquí se denomina la economía kenótica de la fe y, en ese sentido, se apuntan algunas de las oportunidades que el cristianismo puede encontrar en este tiempo en el que nos toca vivir.
«Escuchar, dialogar y discernir» con las mujeres
Authors: Estévez López Elisa , Martínez-Gayol Fernández, ACI Nurya
Published: September 2022

En este artículo hemos querido señalar algunos de los retos ante los que se encuentra hoy una Iglesia llamada e involucrada en un camino sinodal que reclama de ella un ejercicio mucho más exigente de «escucha, diálogo y discernimiento», en particular, con las mujeres que la conforman, y con las mujeres en general. «Escucha y diálogo», en primer lugar, con las mujeres en la diversidad de contextos y culturas (reto 1), y sobre las cuestiones emergentes que afectan sus vidas (reto 2); y «discernimiento», en segundo, de su contribución en los ámbitos y procesos de toma de decisiones en la Iglesia (reto 3), así como de una necesaria revisión de la cuestión de los ministerios (reto 4). Condiciones de posibilidad ineludibles, para avanzar hacia el futuro como una verdadera Iglesia sinodal, de las que brotan estos desafíos que no pretendemos analizar, pero sí mostrar con seriedad y responsabilidad, la urgencia de reflexionar y dejarnos transformar por ellos.
¿Qué caminos nos abre «Episcopalis communio» de cara a una reforma sinodal de la Iglesia católica?
Authors: Borras Alphonse
Published: September 2022

A partir de unas consideraciones (no solo) semánticas sobre los conceptos de reforma y de conversión (1) cuyo contenido se ve determinado por la sinodalidad (2), el artículo presenta el aporte de la constitución apostólica Episcopalis communio [EC] de 2018 en cuanto puede generar una mayor «sinodalización» de la Iglesia católica (3) mediante una articulación entre comunión, participación y misión —el lema del actual proceso sinodal hacia 2023— (3.1), pasando de la escucha a la consulta del pueblo de Dios (3.2) y valorando tanto la doble misión del ministerio episcopal en el marco de una eclesiología de todas las Iglesias (3.3) como una más amplia participación de todos los fieles (3.4). Tal vez uno de los frutos de EC sea repensar (y poner en práctica) la colegialidad episcopal, incluso el primado pontificio, dentro de la sinodalidad eclesial.
El ser y la perspectiva sacramentales
Authors: Granados Jose
Published: September 2022

El artículo quiere avistar líneas fecundas de desarrollo de la sacramentología. Para ello comienza mostrando cómo nuestra época busca lo transcendente en el espacio del cuerpo y en el interrogante sobre la configuración del tiempo de la vida, temas muy cercanos a la lógica sacramental. Se analiza entonces la reflexión reciente sobre los sacramentos y las respuestas que ofrece a estas inquietudes. Se pueden describir, a esta luz, varias trayectorias de investigación: el nexo del septenario con la Eucaristía; el desarrollo de una cristología eucarística; la relación entre lógica sacramental y lenguaje del cuerpo; la capacidad del septenario para configurar el tiempo y la historia; la mirada sacramental sobre la Iglesia y su misión. Se concluye, en fin, que a más de un objeto de la teología por cuyo futuro nos preguntamos, los sacramentos son el lugar donde emplazarnos para descubrir y generar las posibilidades de futuro de toda cuestión teológica.
Editorial
Authors: Leite Letícia Nogueira
Published: September 2022

Editorial
Constipação Intestinal: abordagem terapêutica pelo farmacêutico com foco na eficácia e segurança.
Authors: Umana-Rivas Mariel , Dos Santos Nadine Paula , Cazotti Marina Neves Sanches , Campos de Jesus Rafael do Couto , Lima Soares Maria Clara , Morais Lima Jonathan , Da Silva Oliveira Stanley , Fernandes Lima Nathália Lis , Galato Dayani , Milward de Azevedo Meiners Micheline Marie , Da Silva Emília Vitória
Published: September 2022

Constipação intestinal é um sintoma de causa multifatorial, que provoca muito desconforto ao paciente e pode afetar sua qualidade de vida, motivo de ser uma das queixas mais comuns daqueles que procuram serviços de saúde (1).Muitos pacientes, incomodados pelo desconforto provocado pela constipação, buscam atendimento na atenção primária, incluindo a farmácia comunitária, e realizam a compra de medicamentos que não necessitam prescrição médica.Neste sentido, faz-se importante para o farmacêutico que atua em farmácias comunitárias saber identificar a constipação intestinal, orientar os pacientes especialmente com medidas não farmacológicas e ajudá-lo na escolha do laxante mais adequado ao seu perfil clínico.Por esse motivo, este texto foi elaborado abordando a segurança e eficácia dos laxantes disponíveis no Brasil, de modo que os farmacêuticos possam ajudar seus pacientes no manejo deste problema de saúde. Para tanto, buscou-se por textos que abordam o tema de constipação e seu tratamento, focando nas estratégias não farmacológicas e medicamentos isentos de prescrição médica.
Train Support Vector Machine Using Fuzzy C-means Without a Prior Knowledge for Hyperspectral Image Content Classification
Authors: Taher Akar H.
Published: September 2022

In this paper, a new cooperative classification method called auto-train support vector machine (SVM) is proposed. This new method converts indirectly SVM to an unsupervised classification method. The main disadvantage of conventional SVM is that it needs a priori knowledge about the data to train it. To avoid using this knowledge that is strictly required to train SVM, in this cooperative method, the data, that is, hyperspectral images (HSIs), are first clustered using Fuzzy C-means (FCM); then, the created labels are used to train SVM. At this stage, the image content is classified using the auto-trained SVM. Using FCM, clustering reveals how strongly a pixel is assigned to a class thanks to the fuzzification process. This information leads to gaining two advantages, the first one is that no prior knowledge about the data (known labels) is needed and the second one is that the training data selection is not done randomly (the training data are selected according to their degree of membership to a class). The proposed method gives very promising results. The method is tested on two HSIs, which are Indian Pines and Pavia University. The results obtained have a very high accuracy of the classification and exceed the existing manually trained methods in the literature.
Machine Learning Algorithms for Detecting and Analyzing Social Bots Using a Novel Dataset
Authors: Jalal Niyaz , Ghafoor Kayhan Z.
Published: September 2022

Social media is internet-based technology and an electronic form of communication that facilitates sharing of ideas, documents, and personal information. Twitter is a microblogging platform and is the most effective social service for posting microblogs and likings, commenting, sharing, and communicating with others. The problem we are shedding light on in this paper is the misuse of bots on Twitter. The purpose of bots is to automate specific repetitive tasks instead of human interaction. However, bots are misused to influence people’s minds by spreading rumors and conspiracy related to controversial topics. In this paper, we initiate a new benchmark created on a 1.5M Twitter profile. We train different supervised machine learning on our benchmark to detect bots on Twitter. In addition to increasing benchmark scalability, various autofeature selections are utilized to identify the most influential features and remove the less influential ones. Furthermore, over-under-sampling is applied to reduce the imbalance effect on the benchmark. Finally, our benchmark compared with other stateof-the-art benchmarks and achieved a 6% higher area under the curve than other datasets in the case of generalization, improving the model performance by at least 2% by applying over-/undersampling.
The role of tradesmen and craftsmen in Mersin urban economics: An analysis of institutional, sectoral-based and location of activity
Authors: Yaman Ahmet
Published: September 2022

Urbanization is not only a concentration of humans in city areas but also, the consumption and production activities that are comprised in urban space. In this sense, goods and services are developed through the urban economic actors, through labor, economic diversity, and prosperity. This article reviews the relationship between urban economics and tradesmen & craftsmen (TC). The focus is on analysing tradesmen and craftsmen’s institutional, sectoral-based, and activity location. To do that, the research has adopted the qualitative research method strategy and an instrumental and multiple case study design. The study used the document analysis technique to collect data. It aims to illustrate how urban economics actors conduct their businesses across the city. To clarify that, this article benefits from the urban economi cs notion which explains the relation between urban economics structure and actors. This paper also argues that tradesmen and craftsmen are key actors who produce goods and services in urban economics and it is composed of three main parts, the first of which analyses urban economics notion within the historical background briefly. The structure of Mersin's urban economics is assessed in the second part of this article. Within the scope of the paper, first of all, tradesmen and craftsmen were analysed in terms of the institutional framework, sectoral based, and location-activity. What is evident from this research is that tradesmen and craftsmen both are supported by the state and TC has an institutional organization capacity that is spread whole over the national level. Also, TC provides the city’s production process of goods and services based on sector.
First trimester low maternal serum pregnancy associated plasma protein-A (PAPP-A) as a screening method for adverse pregnancy outcomes
Authors: Kantomaa Tiina , Vääräsmäki Marja , Gissler Mika , Sairanen Mikko , Nevalainen Jaana
Published: September 2022

Objectives

To evaluate different cut-off values of first trimester pregnancy associated plasma protein-A (PAPP-A) in screening for adverse pregnancy outcomes in a retrospective cohort study.

Methods

During the study period of 1.1.2014–31.12.2018, total of 23,482 women with singleton pregnancies participated in first trimester combined screening for chromosomal abnormalities. Maternal serum PAPP-A multiple of medians (MoM) levels were measured, and study population was divided into three study groups of PAPP-A ≤0.40 (n=1,030), ≤0.35 (n=630) and ≤0.30 (n=363) MoM.

Results

Small for gestational age (SGA), preterm birth (PTB) and composite outcome (SGA, hypertensive disorder of pregnancy (HDP) and/or PTB) were more frequent in all three PAPP-A MoM study groups and pre-eclampsia in ≤0.40 and ≤0.35 study groups than in their control groups (p < 0.05). The odds ratio (OR) for SGA varied from 3.7 to 5.4 and sensitivity and specificity from 6.9 to 13.8% and from 95.9 to 98.6%, between study groups. Using PAPP-A ≤0.30 MoM as a screening cut-off instead of PAPP-A ≤0.40 MoM, resulted in approximately 50% reduction in screening detection of SGA and PTB.

Conclusions

PAPP-A ≤0.40 MoM should be considered as a primary screening cut-off for adverse pregnancy outcomes as approximately 23% will develop either SGA, HDP or PTB. It seems to be the best cut-off to screen for SGA.
The Effect of Cellulose Nanofibers on Paper Documents Containing Starch and Gelatine Sizing
Authors: Dadmohamadi Kobra , Mohammadi Achachluei Mohsen , Jafari Mohammad Taghi
Published: September 2022

This study aimed to evaluate cellulose nanofibers and their effects on starch and gelatine as the most common surface sizing substances used in historical paper documents. In this study, cellulose nanofibers with a concentration of 1% by weight were prepared as a suspension with ethanol and used for the treatment of unsized samples and samples containing starch and gelatine sizing. The results showed that the application of cellulose nanofiber treatment increased the pH of unsized samples and samples containing starch sizing. After aging, there was a slight decrease in the pH of the samples. Cellulose nanofiber treatment increased the tensile strength of the samples. After accelerated aging, the tensile strength of samples containing starch and gelatine sizing and treated samples increased compared to untreated samples. Samples containing gelatine sizing and samples containing treated starch sizing showed the least amount of colour changes (∆E), respectively, and had the best colorimetry results. The results of the contact angle test of the samples before and after aging showed that cellulose nanofiber treatment did not increase the resistance of the paper to wetting and did not prevent the paper surface from getting wet.
Vorgehensmodell zur Einführung von Pick-by-Scan
Authors: Dreyer Marlen , Feldmann Carsten , Kaupe Victor
Published: September 2022

Flexibilität, Reaktionsgeschwindigkeit und Lieferzuverlässigkeit bestimmen die Wettbewerbsfähigkeit von Unternehmen. Die Kommissionierung von Waren ist eine wichtige Stellschraube, um diese Wettbewerbsvorteile zu realisieren. Im Rahmen der Industrie 4.0 sind die Optimierungsmöglichkeiten der Kommissionierprozesse zwar durch Digitalisierung und Automatisierung gestiegen. Allerdings sind diese insbesondere im Mittelstand durch die Investitionskosten begrenzt. Ein kosteneffizienter Optimierungsansatz ist die Einführung einer Scanner-geführten Kommissionierung, auch bekannt als Pick-by-Scan. Jedoch fehlt in der Literatur ein strukturierter Leitfaden für die Implementierung, um die Nutzenpotenziale von Pick-by-Scan vollständig zu heben. Dieser Beitrag schließt diese Lücke und stellt ein praxiserprobtes Vorgehensmodell für die Einführung von Pick-by-Scan vor.
Digitale Erfassung von Energieverbräuchen in der Produktion
Authors: Frerichs Tobias , Saulich Katja , Strutzberg Lydia
Published: September 2022

Energieeffizienzmaßnahmen in Unternehmen des verarbeitenden Gewerbes sind ein wichtiger Beitrag zur Senkung von Treibhausgasemissionen und dem Verbrauch fossiler Energierohstoffe. Die digitale Erfassung und Analyse von Energieverbräuchen im Herstellungsprozess bietet hierbei die Möglichkeit, Energieeffizienzpotenziale und -maßnahmen effizient und automatisiert zu identifizieren und umzusetzen. Die resultierende Senkung des Energiebedarfs stärkt zudem die wirtschaftliche Situation des Unternehmens und die Wettbewerbsposition.
Industrielles Transferlernen
Authors: Netzer Markus , Alexander Philipp , Gönnheimer Philipp , Fleischer Jürgen
Published: September 2022

Die wesentliche Herausforderung bei der Übertragung von Verfahren des maschinellen Lernens beruht auf dem hohen Aufwand für das erneute Antrainieren auf Zielmaschinen. Maschinengebundene Hyperparameter sowie gelabelte Daten lassen sich durch den Einsatz von Transferlernen übertragen und effizient an ausgewählten Zielmaschinen adaptieren. Nachfolgend werden Herausforderungen des Transferlernens vorgestellt sowie ein Vorgehensmodell eingeführt mithilfe dessen die Übertragung erleichtert wird.
Effiziente Druckluftnutzung in der automatisierten Produktion
Authors: Gockner Cornelia , Rosemann Bernd , Hansen Barbara , Kukla Cornelia
Published: September 2022

Die Nutzung von Druckluft in der Automatisierungstechnik bietet eine Reihe von Vorteilen. Druckluft ist vielseitig nutzbar, sauber und speicherbar. Außerdem bewegt sie große Lasten und hilft präzise zu positionieren. Dennoch gibt es einen Nachteil: Die Drucklufterzeugung ist energie- und kostenintensiv. Lediglich circa sieben Prozent der eingesetzten elektrischen Energie sind als mechanische Expansionsarbeit nutzbar. Anwender sind daher gut beraten, Druckluftverluste zu vermeiden und sich auf die Suche nach autonomen und prozesssicheren Überwachungslösungen zu machen. Der Beitrag beschreibt die Entwicklung und Anwendung einer kennzahlbasierten Analyse zur Erfassung, Auswertung und Überwachung von Druckluftverlusten am Beispiel automatisierter Produktionsprozesse im Karosseriebau.
Ökonomische Bewertung nachhaltiger Wärmeerzeuger
Authors: Mages Alexander , Sauer Alexander
Published: September 2022

Wichtige Bausteine zur Erreichung der Emissionsziele im Wärmesektor sind die Einführung eines CO2-Preises und die Substitution fossiler Wärmeerzeuger mit nachhaltigen Technologien. Daher wird in diesem Beitrag die Integration nachhaltiger Wärmeerzeuger (Wärmepumpe, Solarthermieanlage und Biomasseheizkessel) in die bestehende Wärmeversorgungstruktur eines Industrieunternehmens untersucht. Mit steigendem CO2-Preis können Amortisationszeiten von unter fünf Jahren für Wärmepumpen und Biomasseheizkessel im Vergleich zur bisherigen Betriebsweise mit einem erdgasbetriebenen Dampfkessel realisiert werden.
Research Directions for Merging Geospatial Technologies with Smart Manufacturing Systems
Authors: Scholz Johannes , Bernstein William Z. , Radkowski Rafael
Published: September 2022

As industrial Internet of Things concepts and technologies continue to be retrofitted onto existing manufacturing infrastructure, geospatial considerations, such as asset localization, registration, and tracking, become more critical to ensure better flexibility, capability understanding, and agility. In response, there have been efforts to merge state-of-the-art Geographical Information Systems and Smart Manufacturing Systems in production environments. However, these solutions are often product- or platform-centric and proprietary, such as (i) computer vision technologies embedded on an automatic guided vehicle and (ii) point cloud translation after 3-D scan within a Product Lifecycle Management solution. Standards exist for various steps and functions within these computer-supported pipelines, but little work exists that tests their scalability and robustness. This paper aims to critically evaluate the current state of the integration of Smart Manufacturing Systems and Geographic Information Science and Technology and identifies the potential overlap between the two fields and lists opportunities for further collaboration. The methodological approach of this paper is two-fold: we utilize (a) a survey with experts in both fields and (b) an algorithmic literature meta-analysis. The results reveal that both fields have concepts that could mutually support each other and that smart manufacturing could benefit from Geographic Information technologies—especially from a standardized representation of indoor environments. The results show a great number of potential overlaps and thus present a preliminary roadmap to foster the integration.
Por uma “aliança afetiva” entre a arqueologia e os saberes tradicionais
Authors: Sallum Marianne
Published: September 2022

Este artigo apresenta o texto da minha aula no concurso público para seleção de docente de Arqueologia, em fevereiro de 2022, na Universidade Federal de Minas Gerais. O conteúdo é uma reflexão fundamentada no campo da Arqueologia do Colonialismo em relação aos saberes tradicionais, ordenado para responder ao tema “Contribuições da Arqueologia para o entendimento da sociedade moderna no Brasil”, definido pela organização do certame. O texto vem dividido em duas partes, com a primeira trazendo a fundamentação teórica; a segunda, com o exame de um caso de pesquisa regional.
De São Vicente a Jacarepaguá
Authors: Alves Peixoto Sílvia , Noelli Francisco , Sallum Marianne
Published: September 2022

O contexto colonial de São Paulo e Rio de Janeiro conectou pessoas Tupiniquim, portugueses e seus descendentes, articulando interesses estratégicos em novas realidades políticas e sociais, como no Engenho do Camorim. Neste cenário, a genealogia de uma importante mulher paulista de São Vicente - Esperança da Costa, permitiu recuar no tempo até sua antepassada Tupiniquim Cecília Rodrigues (nascida c.1505) e suas descendentes, que provavelmente estiveram entre as comunidades de práticas que apropriaram e transformaram a cerâmica comum portuguesa na Cerâmica Paulista. A compreensão desse cenário resulta de vasta quantidade de dados, interpretados através de uma abordagem interdisciplinar sob os pressupostos da persistência das comunidades e da transmissão de conhecimento entre as linhagens de mulheres, que permite explicar a presença de cerâmicas produzidas com as mesmas tecnologias em tempos e lugares diferentes nos últimos 500 anos. Cecília e suas contemporâneas legaram uma herança compartilhada até opresente.
A cerâmica colonial do vale do Macacu, Rio de Janeiro
Authors: Coelho Trindade Cleide , André Torres de Souza Marcos
Published: September 2022

O objetivo deste artigo é apresentar os resultados da análise diacrônica das cerâmicas provenientes de quatro sítios históricos localizados na região do Vale do Macacu, que se situa na margem nordeste da Baía de Guanabara (RJ). Um dos mais importantes centros de produção agrícola do Rio de Janeiro no período colonial, essa região abrigou uma população muito diversa, composta por indígenas, africanos e europeus, que mantiveram diferentes níveis de representação demográfica ao longo do tempo. Buscando entender essa diversidade, este artigo explora a variabilidade diacrônica das cerâmicas de uso doméstico de quatro períodos distintos, compreendidos entre os séculos XVII e XIX. Levando em conta a agência criativa dos diferentes sujeitos envolvidos na produção cerâmica, propomos que aí ocorreu um processo de etnogênese.
Social Affect Regulation in University Students During the COVID-19 Pandemic
Authors: Powers John P. , Burnham Megan , Friedman Hannah , McRae Kateri
Published: September 2022

Given how much time humans spend in social contexts, interest has been growing in socially mediated forms of affect regulation. Historically, though, research on affect regulation has focused on individual forms of regulation, such as cognitive reappraisal. To address this gap, we investigated social affect regulation in university students through an online survey, with a particular focus on social reappraisal. Specifically, we tested whether the frequency with which students communicate with their social contacts is related to how much social reappraisal support they receive from those contacts, and whether social reappraisal support is associated with mental health. Our final sample consisted of 152 undergraduates from across North America who reported on a total of 1,124 social contacts. We consistently found that communication frequency was positively associated with perceived social reappraisal support across several modalities of communication (e.g., text-based, video-based, in-person). However, we observed no associations between levels of social reappraisal support and measures of mental health. This research was part of a preregistered project on social affect regulation in university students in the context of the COVID-19 pandemic (https://osf.io/q7bvw/). Thus, we present findings in relation to this context. These findings underscore that social forms of affect regulation play a significant role in university students’ lives, emphasizing the value of further research into their mechanisms and effects.
The influence of nodule size on clinical efficacy of ethanol ablation and microwave ablation on cystic or predominantly cystic thyroid nodules
Authors: Zhang Ya , Chu Xiaoqiu , Liu Yuling , Zhao Yueting , Han Xue , Hu Xin , Xiang Pingping , Chen Guofang , Liu Chao , Xu Shuhang
Published: September 2022

Objective

To compare the efficacy and safety of ethanol ablation (EA) and microwave ablation (MWA) in the treatment of cystic or predominantly cystic thyroid nodules.

Methods

Patients with cystic or predominantly cystic thyroid nodules intervened with EA or MWA were retrospectively enrolled and divided into EA group (n  = 30) and MWA group (n  = 31). The volume and volume reduction rate (VRR) of thyroid nodules before ablation, and at 3 and 12 months after ablation were compared between the two groups. The effective rate (ER) and incidence of adverse events in both groups were recorded.

Results

The median VRR and ER at 3 months after ablation were significantly higher in EA group than in MWA group (81.30% vs 75.76%, P = 0.011; 76.67% (23/30) vs 51.61% (16/31), P = 0.040), while no significant difference was detected at 12 months (93.39% vs 88.78%, P = 0.141; 86.67% (26/30) vs 87.10% (27/31), P = 0.960). The median VRR of small nodules in EA group was significantly higher than that in MWA group (81.30% vs 71.18%, P = 0.006; 93.40% vs 83.14%, P = 0.032). There was no significant difference of median VRR in medium nodules at final follow-up between MWA and EA group (93.01% vs 89.68%, P = 0.482). Serious adverse events were not reported in both groups.

Conclusion

EA and MWA are both effective and safe in the treatment of cystic or predominantly cystic thyroid nodules. EA is more cost-effective and effective than MWA for small nodules, but it requires more cycles of treatment and may pose a higher risk of postoperative pain compared with MWA.
Hypercalcemia in the setting of HTLV-1 infection and a normal PTHrP level
Authors: Haridas Keerthana
Published: September 2022

Human T-cell lymphotropic virus-1 (HTLV-1) causes adult T-cell leukemia and lymphoma (ATLL) and is a rare but important cause of hypercalcemia. A 53-year-old male with HTLV-1-associated myelopathy presented with acute on chronic bilateral lower extremity weakness and numbness. Initial blood work revealed hypercalcemia with corrected calcium of 16.2 mg/dL (8.5–11.5) with normal levels of phosphorus and alkaline phosphatase. Workup for hypercalcemia revealed parathyroid hormone (PTH) of 14 pg/mL (10–65), 25 hydroxy vitamin D at 19.6 ng/mL (30–100), 1,25 dihydroxy vitamin D at 6.7 pg/mL (19.9–79.3), thyroid-stimulating hormone of 1.265 μIU/mL (0.5–5), undetectable PTH-related protein (PTHrP) and lactate dehydrogenase of 433 U/L (100–220). The urine calcium creatinine ratio was 0.388. Reverse transcriptase PCR was positive for HTLV-1 and negative for HTLV-2. Peripheral blood flow cytometry and lymph node biopsy confirmed ATLL. He received treatment with fluids, calcitonin and denosumab after which serum calcium levels fell (nadir: 7.7 mg/dL) and then normalized. Humoral hypercalcemia in this setting is mediated by receptor activator of nuclear factor-kappa B ligand (RANKL), PTHrP and other cytokines. PTHrP levels depend on levels of the TAX gene product, cell type and lymphocyte-specific factors. Thus, a low level, like in our patient, does not rule out HTLV-1 infection/ATLL as the cause of hypercalcemia. Hypercalcemia is known to be responsive to monoclonal antibodies against RANKL given the compound’s role in mediating hypercalcemia in these cases.

Learning points

Human T-cell lymphotropic virus-1 infection and adult T-cell leukemia and lymphoma are associated with high rates of hypercalcemia and hypercalcemic crises.

Hypercalcemia in these cases is mediated by osteoclastic bone resorption carried out by several agents including receptor activator of nuclear factor-kappa B ligand, parathyroid hormone-related protein (PTHrP), macrophage inflammatory protein 1 alpha, interleukins, etc. A normal PTHRrP does not rule out humoral hypercalcemia of malignancy in this setting, as indicated by this case.

Hypercalcemia in such settings is highly responsive to monoclonal antibodies against RANKL given the role the ligand plays in resorptive hypercalcemia.
Mechanical fragmentation of wheat straw at different plant scales: Pb2+ adsorption behavior and mechanism
Authors: Cao Yaoyao , Xiao Weihua , Shen Guanghui , Ji Guanya , Zhang Yang , Gao Chongfeng , Han Lujia
Published: September 2022

Wheat straw samples at the plant scale (> 1 mm), tissue scale (100 to 500 μm), and cellular scale (30 to 50 μm) were produced to characterize their microstructure and adsorption properties. The effects of changes in the microstructure and adsorption properties on the adsorption capacity of Pb2+ were investigated. The results implied that specific surface areas and pore volumes in the cellular-scale sample were four to five times larger than at other scales, as superfine grinding destroyed the structure of tissues and cell walls. The crystallinity declined significantly from 53% to 34% with decreasing fragmentation scale. Changes in adsorption properties (point of zero charge, acidic functional groups, and cation exchange capacity) were not apparent. The pseudo-second-order model and Langmuir isotherm model fit the experimental data better than alternate models. The adsorption capacity of Pb2+ increased significantly with decreasing fragmentation scale. The main mechanism improving the adsorption capacity of Pb2+ was intensive complexation owing to an increase in cellulose accessibility to water and enhanced chemical reaction activity of the hydroxyl groups, rather than physical and electrostatic adsorption.
Optimization of the Mealy Automaton Circuit in the FPGA Basis
Authors:   University of Zielona Gora, Barkalov Olexandr O. , Titarenko Larysa O. ,   University of Zielona Gora, Golovin Olexandr M. ,   V.M. Glushkov Institute of Cybernetics of NAS of Ukraine, Matvienko Oleksandr V. ,   V.M. Glushkov Institute of Cybernetics of NAS of Ukraine
Published: September 2022

Introduction. The ubiquitous penetration of digital systems into all spheres of human activity has made obvious the desire to reduce hardware costs. If for the implementation of combinational circuits there are standard solutions used in various CAD systems, then for many types of accumulating blocks, which include control devices (CU), there are no standard library solutions. CU circuits, which are a sequential circuit, must be designed first each time because, as a rule, these circuits differ in an irregular structure and a complex interconnection system. The characteristics of the control device have a significant impact on the quality of the digital system, and therefore the issue of designing a control device is a responsible process that, as a rule, requires solving the problem of reducing hardware costs. Methods for solving this problem depend on the features of both the architecture of the control device and the elemental basis. Purpose. The main goal of this work is to reduce hardware costs and power consumption of control devices of digital systems by taking into account features of an element base of the control device and rational organization of micro-command addressing. FPGA (field-programmable logic array) microcircuits, widely used for the implementation of modern digital systems, were chosen as an elementary basis. Methods. To evaluate the effectiveness of solving the problem, we used the methods of set theory, synthesis of automata, and software simulation using Xilinx Vivado CAD. Results. The paper proposes a method for reducing hardware costs in the microprogram Mealy automaton (MPA) scheme implemented on an EMB and LUT basis. The method is based on the use of EMB to implement the logical condition replacement block. It is proposed to implement a part of the output signals (micro-operations) on EMB. The applicability conditions for this approach are shown. An example of the synthesis of MPA using the proposed method is given. All stages of the synthesis are analyzed in detail. Some alternative solutions are proposed and the conditions for their use are shown. Conclusion. Studies have shown that when using one EMB block, our method gives a gain in the number of LUT elements. Comparisons were made with schemes obtained using the Auto, One-hot, and Sequential methods of the Vivado system.
MICROCIRCULATION AND VASOMOTOR FUNCTION OF THE ENDOTHELIUM IN ELDERLY PEOPLE WITH IMPAIRED GLUCOSE TOLERANCE
Authors:   D. F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine, Asanov E.O. , Gavalko A.V. ,   D. F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine, Duzhak G.V. ,   D. F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine, Naskalova S.S. ,   D. F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine, Antonyuk-Shcheglova І.А. ,   D. F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine, Shatilo V.B. ,   D. F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine
Published: September 2022

The peculiarities of microcirculation and vasomotor function of the endothelium and their relationship with resistance to hypoxia in the elderly with impaired glucose tolerance were studied. It has been shown that in the elderly with impaired glucose tolerance, skin microcirculation and vasomotor function of the endothelium are reduced when breathing air. An inverse correlation has been established between disorders of carbohydrate metabolism, the state of skin microcirculation and vasomotor function of the endothelium. The connection between the shift of blood saturation under hypoxic load and indicators of microcirculation and vasomotor function of the endothelium in the elderly with both impaired and preserved glucose tolerance. But in the elderly with impaired glucose tolerance, the strength of these connections is greater.
POSSIBLE IMPORTANCE OF ADENYLATE CYCLASE SIGNALING PATHWAY IN THE SYNTHESIS OF NITRIC OXIDE BY MYOMETRIUM MITOCHONDRIA
Authors:   Palladin Institute of Biochemistry of National Academy of Science of Ukraine, Kyiv, Ukraine, Danylovych Yu.V. , Danylovych H.V. ,   Palladin Institute of Biochemistry of National Academy of Science of Ukraine, Kyiv, Ukraine, Kosterin S.O. ,   Palladin Institute of Biochemistry of National Academy of Science of Ukraine, Kyiv, Ukraine
Published: September 2022

NO synthase activity (mtNOS) in uterine smooth muscle mitochondria under the action of the cAMP/protein kinase A signaling system modulators was studied. The experiments were performed on isolated mitochondria from rat myometrium using the NO-sensitive fluorescent probe DAF-FM-DA. NO synthesis in mitochondria was increased by adenylate cyclase activators NaHCO3 (30 mM) and forskolin (10 μM), as well as phosphodiesterase inhibitor caffeine (1 mM). The addition of ATP (0.5-5 mM) caused a slight increase in nitric oxide synthesis. The effect of ATP was enhanced in the presence of NaHCO3 and caffeine. The intensity of NO formation in mitochondria decreased by approximately 50 % in the case of inhibition of adenylate cyclase activity by the compound KH7 (25 μM). In the presence of the protein kinase A inhibitor PKI (10 nM) NO synthesis in mitochondria was also significantly reduced. When the constitutive NO-synthase inhibitor L-NAME (100 μM) was introduced into the incubation medium, the stimulating effect of the studied compounds on NO synthesis in mitochondria was not observed. These data suggests a possible dependence of mtNOS function on the activity of the cAMP/protein kinase A signaling system in smooth muscle mitochondria.
Teto terapêutico e a adequação do tratamento no Serviço de Urgência – estudo retrospectivo
Authors: Lucas Sandra Ganchinho , Alfaiate Filipe Jorge Pencas , Santos Inês Vieira , Lino Ireneia
Published: September 2022

Introdução: no Serviço de Urgência vive-se um antagonismo constante pela sua natureza direcionada para a patologia aguda e a prestação de cuidados paliativos de qualidade. O nosso estudo tem como objetivo avaliar se a definição de teto terapêutico leva a diferenças na adequação da marcha diagnóstica e terapêutica instituída.Material e métodos: análise retrospetiva descritiva monocêntrica dos doentes que morreram nos primeiros seis meses de 2018 no serviço de urgência do Hospital do Espírito Santo de Évora.Resultados: compararam-se os três grupos de doentes o que não foi definido qualquer teto terapêutico, com o grupo em que iniciaram medidas paliativas e o grupo em que se tomou a Decisão de Não Reanimar. Verificou-se que não existem diferenças significativa entre as idades, o local de residência e as comorbilidades e, com exceção da demência (p= 0,006), existe sim uma diferença no grau de dependência nas atividades da vida diária (p<0,001). Verificou-se que não existem diferenças entre número ou tipo de exames complementares de diagnóstico, mas há algumas diferenças na terapêutica instituída já que no grupo dos doentes em cuidados paliativos a terapêutica com morfina (p<0,001), butilescopolamina (p=0,001) e paracetamol (p=0,004) foi mais frequente. A ventilação invasiva só ocorreu no grupo de doentes sem definição de teto terapêutico (p<0,001), enquanto a oxigénioterapia foi mais frequente nos grupos em Decisão de Não Reanimar ou em cuidados paliativos (p<0,001).Discussão e conclusão: os médicos do serviço de urgência reconhecem que os seus doentes estão em final de vida, adequando parcialmente a terapêutica com vista ao controlo de sintomas, dor e secreções.