bluuebunny/crossref_metadata_2025 huggingface dataset:
DEVELOPMENT OF NEW TYPES OF BAKERY PRODUCTS USING PRODUCTS OF PROCESSING OF COMMON BIRD CHERRY
Authors:   Siberian Federal University, Komissarova Ekaterina
Published: September 2021

The article substantiates the necessity and relevance of increasing the nutritional value of bakery products, as well as the possibility of using dried ground bird cherry (bird cherry flour) for these purposes. The influence of various dosages of the introduced additive on the structural and mechanical properties of the sponge and dough during fermentation is considered. The evaluation of organoleptic and physic-chemical quality indicators and finished bakery products made using bird cherry flour was carried out. The optimal dosage of bird cherry in bakery products is determined based on the calculation of a complex quality indicator. The level of satisfaction of the daily human need for physiologically functional food ingredients at the expense of 100 g of the developed product is calculated.
RESOURCE-SAVING TECHNOLOGY FOR GERMINATING SOY BEANS
Authors:   Siberian Federal University, Zayceva Nadezhda
Published: September 2021

The article describes the relevance of using soybean sprouts in the nutrition of the population, and, consequently, the feasibility of developing resource-saving technologies for sprouting soybeans. The influence of various technological parameters (temperature, humidity, convection) on the rate of germination of soybeans in a steam convection apparatus has been determined; the organoleptic indicators of the quality of sprouts were evaluated for various parameters of germination. An rational technology has been developed for germinating dry soybeans to sprouts 5 cm long. The possibility of extending the shelf life of the obtained soybeans by means of intensive cooling and vacuum packaging has been studied; the storage period is set. The nutritional value of the resulting product was assessed.
Analytical Approach to the Design of Joint Motion Control of the Egratic System " Skipper-Ship"
Authors: Tyrva V. O. , Saushev A. V.
Published: September 2021

The article deals with the problem of designing a joint control of the movement of a water transport object — the ergatic system " ship-to-ship" . Joint motion control is presented in mathematical form on the basis of the model of actions and responses of the human operator and the machine, adopted in engineering psychology for the " human-machine" systems. The model is formalized by composing mathematical models of the plane motion of the ship and the movements of the controls of the propellers (propellers) and rudders of the ship. For the ship’s human-machine interface, it is proposed to use a new type of apparatus, with the help of which the control actions on the control body from the boatmaster and the control automaton of the ergatic system are combined.

For the mathematical description of virtual signals of discrete control in solving problems of target designation and planning, a method for constructing a set of incomplete representations of elementary movements in the state space of the " skipper-ship" system is proposed. The numerical estimates of pairwise different representations of elementary movements and discrete control signals that implement transitions from one elementary movement to another by influencing the propellers and rudders of the ship using the ship’s human-machine interface controls are obtained.

In order to unify the anthropomorphic control of ship movement at the target designation and planning levels, it is proposed to use templates from several discrete control signals, based on the experience of navigation and solving mathematical programming problems. The solution of the practical problem of optimal anthropomorphic control of the vessel movement from the mooring wall to the lock chamber is obtained, which provides for the implementation of a sequence of ten discrete control signals and two control templates. A method is proposed for estimating the influence of signal, parametric, and coordinate uncertainties on the position of the image point in the state space of the " su-driver-ship" system relative to the nominal trajectory of the program motion. The regions of interval representations of uncertainties in the subspace of the ship’s " time-position-speed" states are obtained. The procedure for correcting the a priori description of nominal anthropomorphic control is considered on the basis of control patterns and analysis of rectangles of uncertainty in the subspace of states of the " skipper-ship" system.
Methods and Algorithms for Correcting Kinematic Equations in the Problem of Determining the Orientation of an Object
Authors: Aleshkin V. V. , Zrazhevsky R. A. , Golovanov P. N. , Marusich V. O.
Published: September 2021

Algorithms of a strapdown inertial orientation system with an inertial measurement module consisting of a three-component gyroscope, accelerometer, and magnetometer are considered. The aim of the work is to improve the algorithms for processing sensor information to ensure the asymptotic stability of the system, tuning for the Schuler period and the low-pass filter with a given bandwidth. The kinematic Poisson equations with positional and integral-positional correction based on the information of accelerometers and magnetometers are considered. The stability and frequency characteristics of the system in relation to the sensor output signals are analyzed. It is shown that the positional correction in each channel does not allow you to adjust the system for the Schuler period. The integral-positional correction allows this adjustment, but in relation to the gyroscope signals, the system is a bandpass filter and does not suppress noise in the bandwidth. The advantages of using positional correction with cross-links in the sense of tuning the frequency characteristics of the system to the Sharper frequency and the third-order low-pass filter are shown. The analysis of the influence of angular velocities confirmed the asymptotic stability of the system with their changes in a given range. The results of mathematical modeling confirmed the compensation of errors in the initial orientation system display, the reduction of noise power in the estimates of the orientation angles in relation to the noise in the sensor signals, and the ability to configure the system for the Schuler period.
Application of Additive Technologies for Manufactoring Non-Electronic Components of Microsystems
Authors:   Byelorussian State Agrarian Technical University, Minsk, 220023, Republic of Belarus, Tolochko N.K.
Published: September 2021

It is problematic to apply traditional microtechnologies for the manufacturing three-dimensional (3D) components of microsystems due to a number of inherent disadvantages. It is much more promising to use additive technologies for these purposes. In present paper various additive technologies used for manufacturing non-electronic components of microsystems as well as various non-electronic components manufactured using these technologies are considered. The peculiarities of the implementation of additive technologies in the manufacture of non-electronic microcomponents are discussed. More than 20 types of additive technologies characterized by different principles for the implementation of 3D printing processes are presented and their brief description is given. Most of these technologies allow manufacturing the components with micrometer feature sizes and some of them — with nanometer feature sizes. Microcomponents produced by additive technologies are intended for use in micromechanics, microoptics and microfluidics. Many examples of such microcomponents are given with indication of their typical feature sizes. Additive technologies make it possible to create both individual parts of microdevices and completely finished micro-devices. Microcomponents are mainly made from photopolymers and thermoplastics, as well as metals. Among additive technologies those that provide the multi-material 3D printing as well as the embedding of discrete components into printed microdevices are especially promising. It is expected that in near future additive technologies will be widely used in the production of various non-electronic components of microsystems.
Characterization of Waste Tire Pyrolysis Products by GC, ICP-MS, TGA and DSC
Authors: UĞUZ Gediz , AYANOĞLU Abdülkadir
Published: September 2021

The huge amount of waste tires (WTs) have been disposed to surroundings which cause dangerous effect on nature. Owing to recycled WTs, the pyrolysis is a good technique to dismiss harmful effect of the WTs, by converting into gas, liquid and solid. The present study has two steps of liquefaction at a batch reactor. Firstly, conversion of the WTs into gas, waste tire oil (WTO) and char. Then the WTO were blended with calcium oxide (CaO) or natural zeolite (NZ) at different ratio and pyrolyzed to obtain high quality oil, similar to gasoline fuel (GF) or diesel fuel (DF). The distillation curve is a good key to define fuel quaility. Thus, 10% CaO-WTO blend curve near to the DF. Unfortunately, the mixture was distillated at 54 oC, lower than the DF. Therefore, the blend was separated into two fractions due to intial-final boiling points as 150 oC to 360 oC, named as Diesel like fuel (DLF); between 54 oC to 150 oC, called as gasoline like fuel (GLF). Finally, samples were analyzed to characterizate by GC, ICP-MS, TGA and DSC for similarities of conventional fuels. Based on GLF and DLF results, they can be burned in engine.
Yüksek Çözünürlüklü İnsansız Hava Aracı (İHA) Görüntülerinden Karayolların Tespiti
Authors: YİĞİT Abdurahman Yasin , UYSAL Murat
Published: September 2021

Şehir planlaması, meteoroloji, ormancılık, madencilik, tarımsal jeoloji, peyzaj ve haritacılık gibi birçok alanda yüksek çözünürlüklü görüntülerde bulunan bilgilere çeşitli amaçlar için ihtiyaç duyulmaktadır. Yüksek çözünürlüğe sahip görüntülerde yoğun veriler bulunmaktadır ve bu yoğun verilerden istenen detayların otomatik veya yarı otomatik tespiti yapılacak çalışmaya hız, maliyet ve doğruluk açısından katkı sağlamaktadır. Gelişmiş detay çıkarma yöntemleri sayesinde otomatik detay tespiti daha hızlı ve kolay hale gelmiştir. Bu çalışmada İnsansız Hava Aracı (İHA) ile görünür bölgede (kırmızı-yeşil-mavi bant) elde edilen yüksek çözünürlüklü ham veriler değerlendirilip nesne tabanlı sınıflandırma yaklaşımı ile otomatik karayolu tespiti yapılmıştır. Nesne tabanlı sınıflandırma yöntemiyle; konumsal, spektral ve bağlamsal bilgi gibi farklı nesne özelliklerine göre sınıflandırılmanın mümkün olduğu gösterilmiştir. Çalışma sonucunda, karayoluna ait ortofoto görüntüsünden nesne tabanlı yaklaşım ile tespit edilen yol ağının yer gerçeği ile ne kadar uyumlu olduğunu belirlemek için iki farklı analiz yapılmıştır. Sınıflandırma kalitesini kontrol etmek için TTA maskesine dayalı hata matrisi yaklaşımı, halihazır harita ile uyumunu araştırmak için ise hata matrisi (Confusion-matrix) ile analiz yapılmıştır. Analiz sonucunda kapa istatistiği 0.7958, genel doğruluk ve üretici doğruluğu ise sırasıyla 0.7520, 0.8158 hesaplanmıştır.
Lisanslı Fotovoltaik Güneş Enerji Santrali Yatırımının Finansal Analizi: Van İli Örneği
Authors: YALILI Mehmet
Published: September 2021

Bu çalışmada, lisanslı ve şebekeye bağlı 1 MW gücündeki fotovoltaik GES yatırımının günümüz ekonomik koşullarına göre finansal analizi yapılarak yatırımın kârlı olup olmadığı incelenmiştir. Bu kapsamda öncelikle ülkemiz güneş enerjisi potansiyel atlasından faydalanılarak Van ili Edremit ilçesinin GES kurulumu için uygunluğu değerlendirilmiş ve arazi seçimi yapılmıştır. Enerji hesaplamalarının yapılmasında PVGIS çevrim içi veri tabanından yararlanılmış ve seçilen arazi için yıllık elektrik üretim miktarı hesaplanmıştır. Yatırımın ekonomik ömrü olan 25 yıl boyunca panel veriminde yıllık %0.7 oranında lineer düşüş olacağı varsayılmıştır. Yatırımın fayda ve masraf unsurları, her birine karşılık gelen güncel yatırım maliyetleri belirtilerek detaylı şekilde açıklanmıştır. Yatırımın tamamen öz sermaye veya on yıl geri ödemeli TurSEFF yenilenebilir enerji kredisi ile yapılması durumları için geri ödeme süresi (GÖS), net bugünkü değer (NBD), iç kârlılık oranı (İKO) ve fayda/masraf oranı (FMO) yöntemleri kullanılarak finansal analiz gerçekleştirilmiştir. Mevcut alım garantisi fiyatları ile serbest piyasada gerçekleşen elektrik satış fiyatları (piyasa takas fiyatı) esas alınarak yapılan değerlendirmeye göre, %10 kâr payı beklentisi altında yatırımın öz sermaye ile yapılması halinde NBD pozitif, FMO 1’den büyük ve İKO %22.35 olarak hesaplanmış, bu durumda yatırımın geri ödeme süresi 4 yıl olarak bulunmuştur. Yatırım maliyetlerinin kredi ile karşılanması halinde ise NBD negatif olarak hesaplanmış, ayrıca FMO 0.928, İKO %6.76 ve geri ödeme süresi 9 yıl olarak bulunmuştur. Finansal analize örnek olarak seçilen Van ilinde gerçekleştirilen 1 MW GES yatırımının öz sermaye ile yapılması halinde kabul edilebileceği, ilk yatırım maliyetlerinin tamamen kredi ile karşılanması halinde ise yatırımın yapılabilir olmadığı sonuçlarına ulaşılmıştır.
Yatay Toprak Isı Değiştiricilerdeki Basınç Kayıplarının İki Boyutlu Bilgisayar Simülasyonları ile Enerji Verimliliği Bakımından Değerlendirilmesi
Authors: AMETİ Azam , DEĞİRMENCİ Adil , ÇAKMAK Mehmet Ekrem
Published: September 2021

Bu çalışmada yedi farklı geometrik tasarıma sahip yatay toprak ısı değiştiricilerin enerji verimini etkileyen basınç kayıpları bilgisayar destekli simülasyonlar aracılığı ile incelenmiştir. 30 m^2’lik (6mx5m) bir bahçe alanında kullanılmak üzere tasarlanan modeller, denklemlerin hesaplama kolaylığı açısından, iki boyutlu olarak oluşturulmuştur. Her bir tasarım ısı değişim yüzey alanları, basınç kayıpları ve enerji verimlilikleri açısından karşılaştırılmıştır. Enerji verimlilikleri açısından karşılaştırılmaları ısı değişim yüzey alanlarının basınç kayıplarına oranı olarak tabir edilen enerji kazanım oranı değerleri üzerinden yapılmıştır. Elde edilen sonuçlara bakıldığında Tasarım-6’nın en yüksek ısı değişim yüzey alanına (6,9681m^2), en düşük basınç kaybına (88,9790kPa) ve aynı zamanda en yüksek enerji kazanım oranına sahip olduğu (0,0783m^2 kPa^-1) görülmüştür. Her ne kadar diğer tasarımlara göre Tasarım-6 en enerji verimli gözükse de işletim ve bakım açısından değerlendirildiklerinde diğer tasarımlar yek pare olarak kullanılabileceklerken Tasarım-6’nın çok fazla bağlantı elemanı içermesinden dolayı pratik kullanımının riskli olduğu düşünülmektedir. Sonuçların projenin geliştirilmeye devam edilmesi açısından çok verimli olduğu görülmüştür.
To forensic casuistry
Authors: Eichenwald L. I.
Published: September 2021

This forensic case deserves, in our opinion, some attention, both from the everyday point of view, and by the nature of the clinical picture, which forces us to stop a little longer when deciding which category of disorder to attribute the condition described below.
Soliar. About the essence of hysteria. Zum Wesen der Hysterie. Zeitschr. f. d. ges. Neurol. u. Psych. Sonderabdruck aus B. X. H. 3.
Authors: Averbuch R.
Published: September 2021

The author prefaces his study with a historical review of the study of hysteria and critical analysis of modern theories of this issue.
Is mercury injected into the body for therapeutic purposes released into the spinal fluid?
Authors: Lazarev V.
Published: September 2021

Is mercury injected into the body excreted into the spinal fluid? This question occupied us with practical and theoretical points of view. On the practical side, we were interested in knowing how much we can count on the circulation of mercury in the spinal fluid and, therefore, on its direct action on the nervous tissue due to the communication of the perivascular (and pericellular) spaces with the sub-arachnoid. If mercury is released into the spinal fluid, it is necessary to search for the therapeutic effect (syphilis of the nervous system) of the drug that quickly and in large quantities passes into the spinal fluid. On the theoretical side, the issue of mercury release is of interest for solving the broader issue of the nature of spinal fluid in general. As is known, there is currently no agreement on this account. Is the spinal fluid transudate, the secretion of the vascular plexus epithelium or the sui generis lymph of the brain itself. In favor of the second1 views are inclined by Schultze, Imamura, Raubitschek, Molt, and others in favor of the last but Spina2 (also Lewandovsky and Blumenthal3. The first view is generally accepted. We thought that the saturation of blood with mercury, which happens with prolonged introduction of it into the body, should lead to the appearance of at least traces of it in the spinal fluid, if the latter is transudate. If the last secret, then apriori nothing can be predicted; extraction depends on the chemical and physical properties of the epithelium itself; the epithelium can secerne one substance and not pass another. The number of substances found so far in the spinal fluid when injected into the body is very limited. When the brain (and membranes) was normal, the substances introduced by the authors did not completely enter the spinal fluid. Widal, Monod4, Sicard was found in tuberculous meningitis iod when giving it during 2-3 days for 3-5 grams only in 3 cases. Guinon and Simon found only 1/2 cases of tuberculous meningitis; no iodine was found in cases of cerebrospinal meningitis. With uremia, Costaigne found iod and methylene blue. Sicard and Widal didnt find it. Gilbert and Castaigne found bile pigment in jaundice. Sicard denies. Archard Loeper5 did not find the lithium when it was injected into the blood. Regarding the fate of mercury introduced into the organism, there are no indications in the literature6.
A case of a combination of Paralysis agitans and Morbus Basedowii
Authors: Tanatar L. S.
Published: September 2021

In March 1911, a patient was admitted to our clinic, taken with the diagnosis of Paralysis agitans, all the symptoms of which were evident. But a more detailed study and further observation showed with certainty that we do not really have a pure case of Paralysis agitans, since, in addition to the symptoms inherent in Paralysis agitans, such as: general rigidity of the muscles of active, immobility of the trunk, characteristic slowness of maneuver , diminishing with volitional movements, there was still a whole series of symptoms that did not fit into the picture of tremor paralysis.
Max Löwy. The scope of one phenomenon of uneasiness: hallucination of a call by name (in connection with delusions of attitudes or without such). Ueber eine Unruheerscheinung: Die Hallucination des Anrufes mit dem eigenen Namen (ohne und mit Beachtungswahn). Iahrbüchern für Psychiatrie und Neurologie XXXIII. Band
Authors: Averbuch R.
Published: September 2021

The author summarizes the results of his research on this issue as follows:1. Hit on the shoulder, nod, exclamations hey, hello, being called by name all these impressions have the common feature that they all mean a call, a call. Their task is to draw the attention of a given person to an event that is about to take place and to cause him a feeling of expectation of something undetermined, but having an important meaning for him.Thus, a certain state of mind is created in the given person called, which gives the words or gestures addressed to him the character of a call.This state of mind is formed on the one hand from the feeling that these words or gestures mean this particular person, refer directly to him, on the other hand, from a feeling of undefined expectation and a sense of importance, significance (Importanrgefhl).There is a strong associative connection between the mental state of the call and the auditory impression of the pronunciation of one's own name.2. The main rule of the mental process is that the associative path between two mental elements can be traversed in both directions.
General surgery department with the i. F. Bush clinic
Of the s. M. Kirov military medical academy
(historical notes to the 220th anniversary of the foundation)
Authors: Kotiv Bogdan N. , Kosachev Ivan D.
Published: September 2021

The article is dedicated to the 220th anniversary of the founding of the General Surgery Department of the S. M. Kirov Military Medical Academy. During the time the department was headed by famous representatives of surgery of those times. The representatives of the General Surgery Department made a significant contribution to the development of surgery in our country, subsequently being the heads of surgical departments and medical institutions. Historically, the academic disciplines taught at the department were the primary link in the education program in surgery at the academy. Most of the heads of the department had the experience of participating in military campaigns, which is necessary for education at a military university. Traditionally, the department scientific research were devoted to the study of the wound process, wound infection, combat injuries, oncology, vascular and abdominal surgery. At present, there is currently a continuity in the formation of educational and methodological materials for various categories of students, scientific developments on topical problems of surgery have been going on (4 figs, bibliography: 4 refs).
ENDOSCOPIC ESOPHAGEAL STENTING AS A METHOD OF SELECTING AND ELIMINATING DYSPHAGIA SYNDROME IN ESOPHAGEAL STENOSIS
Authors: Belevich Valeriy , Vanusa Sergey , Brednev Anton , Kurlova Olga
Published: September 2021

To assess the experience of stents application, formulate the main indications and contraindications for the esophageal stenting, prove that the esophageal stenting with self-expandable metal stents is considered as the treatment of choice in incurable patients. Within the period from 2007 to 2018. 78 patients have treated for the cancer of esophagus and gastric cardia, 2 patients with benign esophageal strictures were subjected to stenting at the general surgery department of the S.M. Kirov Military Medical Academy. The group of patients included 53 men and 17 women. 60 patients with dysphagia grade IIIIV have been examined, 6 of them with trachea-esophageal, 2 esophageal-pleural fistulas formed during the tumor disintegration, 2 patients were treated for burn strictures of the esophagus. M. I. Tech's esophageal stents of Korean firm were used. Insertion was carried out by short endoscopic delivery systems of a small diameter. Satisfactory evaluation of the stent state and adequate stent expansion, absence of any misplacement were considered as an indication for starting oral food intake. Patients may be allowed to go home shortly after an esophageal stent procedure (the same day). The first day the patient could use water and foods need to be liquid, moist and soft, in the following days it was possible to increase the density of products. The study found that stenting of the esophagus is a current method of endoscopic surgery, aimed at the expanding and maintaining of the lumen of the esophagus by means of the inserted self-expandable stents. Esophageal stenting possesses by fewer complications unlike other techniques. The role of palliative treatment (for example, stenting) is considered to reduce dysphagia, improve the quality of life and increase life expectancy
Modern approaches in treatment of diabetic foot syndrome
Authors: Risman Boris V. , Ivanusa Sergey Y. , Yanishevskiy Andrey V. , Shayakhmetov Rauan E.
Published: September 2021

The article is devoted to practical issues of the clinic, the diagnostic algorithm and tactics of treatment of purulent-necrotic complications of diabetic foot syndrome. Studying the wound process in patients with purulent-necrotic complications of diabetic foot syndrome using modern methods. The efficiency has been proved and an algorithm has been proposed for the use of some physical methods of sanitation in the local treatment of diabetic foot syndrome. The proposed methods of treatment make it possible to reduce the number of amputations and reduce mortality in patients with purulent-necrotic complications of diabetic foot syndrome (1 figure, 1 table, bibliography: 9 refs).
The case of the multistage treatment of acute pancreatitis using a variety of minimally invasive techniques
Authors: Ivanusa Sergey Y. , Lazutkin Maksim , Shershen Dmitriy , Chebotar Anton
Published: September 2021

Treatment of acute pancreatitis and infectious complications is a complex multidisciplinary task. The use of traditional surgical procedures for the rehabilitation of foci of pancreatogenic infection often aggravates the course of the disease, leads to the development of postoperative complications, does not improve the results of treatment. On the contrary, the use of minimally invasive techniques avoids additional surgical injury. The case of stage treatment of acute pancreatitis and its purulent-septic complications with the use of minimally invasive technologies is presented to the readers.
Diseases of the digestive organs and COVID-19
Authors: Grinevich Vladimir B. , Kravchuk Yuriy A.
Published: September 2021

With a new coronavirus infection (COVID-19), gastroenterological symptoms are often detected, which is due to both the damage to the digestive organs by the SARS-CoV-2 coronavirus and the exacerbation of chronic diseases, as well as aggressive multicomponent therapy. The severity of gastroenterological manifestations, primarily impaired liver function, is associated with a more severe and complicated course of COVID-19 infection. Numerous mechanisms of damage to the digestive organs in COVID-19 have been identified: direct damage by the virus due to resuscitation and multicomponent therapy, impaired central and peripheral nervous regulation, immunothrombotic syndrome, virus persistence in the gastrointestinal tract, induction of autoimmune reactions by the virus, humoral disorders (changes in serotonin levels, bradykinin, activation of mast cells). Violation of the microbial-tissue complex of the intestine and the permeability of the intestinal barrier, induced by the SARS-CoV-2 virus, ensures the formation and progression of chronic systemic inflammation, cytokine aggression, insulin resistance, endothelial dysfunction, which affect the severity of the infection. Therapy for patients with COVID-19 should include therapeutic approaches aimed at correcting disorders of the intestinal microbiota, intestinal barrier permeability, and relief of gastroenterological manifestations (bibliography: 20 refs).
From theory to practice: immunotherapy of purulent-inflammatory diseases and purulent-septic complications
Authors: Alekseeva Nataliya Yu. , Dyumnikov Denis A. , Solovyev Ivan A. , Kalyuzhin Oleg V.
Published: September 2021

Lack of anti-infective protection is one of the reasons for the occurrence of purulent-inflammatory diseases of the skin, soft tissues and purulent-septic complications in the postoperative period. Immunocorrective therapy is extremely relevant in surgical practice, and it can be used both for the prevention and treatment of postoperative complications. In this regard, special attention should be paid to low molecular weight fragments of peptidoglycan of cellular bacteria muramyl peptides.

The study included 65 patients with purulent inflammatory diseases, of which 35 men aged 2355 years with chronic recurrent pyoderma (ostiofolliculitis, folliculitis, sycosis, furunculosis), and 30 patients aged 18 to 65 years with purulent inflammatory diseases of soft tissues, mainly abscesses and phlegmons of various localization without pronounced concomitant pathology. The examination included 26 patients with purulent-septic complications in the postoperative period. The patients included in the study were divided into 2 equal groups: 1 is the main group, in which patients received intramuscularly Polimuramil 200 mg daily for 5 days in addition to treatment; Comparison group 2, in which patients received only standard treatment. The clinical symptoms of pyoderma were assessed from day 0 to day 7, then on day 14, after 1 and 6 months of the study. Blood samples were taken from all patients for hematological and immunological studies. The timing of the appearance of granulations was monitored daily.

The inclusion of Polimuramil in the complex treatment of pyoderma accelerated the regression of the main clinical manifestations of the disease and promoted the induction of stable remission. In patients with soft tissue infections, Polimuramil increased the degree of regression of the depth and area of the wound and accelerated the appearance of granulations. The clinical efficacy of Polimuramil in patients with purulent-septic complications in the postoperative period correlated with a decrease in CRP and procalcitonin levels. The study confirms the effectiveness of Polimuramil in the treatment of purulent-inflammatory diseases and purulent-septic complications in the postoperative period and its high immunomodulatory potential (8 figs, 2 tables, bibliography: 5 refs).
The effect of life kinetic training on learning of shot put glide technique and motoric parameters
Authors: Orhan Özlem , Çetin Ebru , Çimen Polat Sezen , Yarım İmdat
Published: September 2021

This study determined the effect of life kinetic (LK) training on the learning of glide techniques, shot performance and motor parameters of students in the faculty of sports sciences. A total of 54 students, 24 females (19.2±2.1years) and 30 males (19.6 ± 1.9 years), who were studying in faculty of sports sciences participated in the research.  Students participated in the track and field lesson twice a week for 12 weeks. The experimental group was made to exercise LK training for 30 minutes before each lesson after the general warm-up. Before and after the 12-weeks of training, measurements were taken from students two times. Willcoxon T-test was applied in order to determine whether or not there were differences between the pre-test and post-test which were applied before and after the training program. Mann Whitney U test was used in order to determine whether or not there was a difference between the two groups. Statistical significance level was taken as p<0.05As a result of the research, statistically significant differences were determined between the experimental and control group in the shot put distance, glide technique, agility, visual reaction, auditory reaction parameters. In brief, it may be stated that LK training positively affected the development of skills and technical learning of students.
Aplicación Web para la Predicción del Comportamiento de la Población Vinculada a una Compañía de Seguros Funerarios
Authors: Saint-Priest Velásquez Yana Elida
Published: September 2021

El núcleo de negocio de la empresa Servivir se basa en servicios a partir de la venta de planes exequiales o funerarios. En su proceso realiza análisis de datos para comprender el comportamiento de los clientes, sin embargo, no cuentan con las herramientas especializadas para el análisis de datos que haga el proceso más eficiente y confiable; es así como nace la idea de este proyecto cuyo objetivo es la construcción de una aplicación web que permite realizar análisis de datos y presentar los resultados de los mismos a través de reportes gráficos. El proyecto se diseñó bajo la estructura metodológica incremental de desarrollo de software, también se implementaron lineamientos y artefactos de la metodología SCRUM. Los resultados mostraron información relevante del comportamiento de los asociados a Servivir, se encontró concentración poblacional en tres entidades asociadas, lo cual genera un riesgo financiero en caso de retiro por fallecimiento. Al final se concluye que la aplicación reduce los tiempos de análisis de información en un 99,98%, con lo cual  se considera altamente funcional.
Uso del operador swap genera soluciones eficientes computacionales en un caso de enrutamiento de vehículos con enfoque de ventanas de tiempo
Authors: Mantilla Mejía Javier Darío
Published: September 2021

Introducción: La programación de ruteo de vehículos con cumplimiento de servicio es una necesidad de las empresas de logística en busca de su ventaja competitiva. Objetivo: El objetivo del siguiente trabajo es determinar la programación al mínimo costo de enrutamiento de vehículos para una flota homogénea, cumpliendo con las ventanas de tiempo. Método: Los costos de logística, incluido el costo de operación de ruta de vehículos, son parte fundamental de la disminución de costos, un aumento directo de las ganancias en las empresas, que va acompañado de la creación de una ventaja competitiva. El modelo matemático utilizado y el desarrollo del algoritmo de optimización combinatoria para un VRPTW se exponen mediante el uso de una matriz de ahorro y heurísticas de swap. Resultados: El algoritmo de ahorro establece la fase de construcción inicial en base a la distancia mínima, y el algoritmo de swap realiza intercambios muy rápidos a través de 12 interacciones para un caso de 300 clientes, buscando mejorar a través de la reducción de tiempos muertos, logrando ahorros del costo total de 71,41% sobre el coste inicial del algoritmo de ahorro. Conclusiones: Para cálculos de casos de CVRPTW de 300 nodos, el algoritmo swap consigue tiempos computacionales menores a 30 segundos.
Iğdır Koşullarında Ot Verim ve Kalite Özellikleri Açısından Uygun Yem Bezelyesi Çeşitleri ve Kışlık Ekim Zamanlarının Belirlenmesi
Authors: TEMEL Süleyman , KESKİN Bilal , ÇAKMAKÇI Selma , TOSUN Ramazan
Published: September 2021

Çalışmanın amacı ot verim performansı açısından Iğdır bölge ekolojisine uygun yem bezelyesi çeşidi ve kışlık ekim zamanlarını belirlemektir. Bu doğrultuda 2018-2019 ve 2019-2020 yetişme sezonunda dört yem bezelyesi çeşidi (GAP pembesi, Kirazlı, Taşkent ve Özkaynak) ile bunların 3 farklı kışlık ekim zamanı (Ekim sonu, Kasım başı ve Kasım sonu)’nı içeren bir çalışma planlanmıştır. Araştırma Iğdır Üniversitesi Tarımsal Uygulama ve Araştırma Merkez Müdürlüğü araştırma sahasında tesadüf bloklarında bölünmüş parseller deneme desenine göre üç tekerrürlü olarak kurulmuştur. Araştırma sonucunda incelenen parametreler üzerine çeşitlerin (asit deterjan lif oranı hariç, diğer özelliklerde), yılların (çiçeklenmeye başlama zamanı, dal sayısı, kuru madde oranı, ham protein oranı, asit deterjan lif, nötr deterjan lif ve nispi yem değeri) ve ekim dönemlerinin (sadece çiçeklenemeye başlama zamanı) etkisi önemli bulunmuştur. Sonuç olarak incelenen parametreler göz önüne alındığında, yüksek verim ve kaliteye sahip ot üretimi için Taşkent ve Özkaynak çeşitlerinin bölge ekolojisi için uygun olduğuna karar verilmiştir. Ayrıca ekim zamanlarının etkisi her ne kadar önemli bulunmasa da Kasım ayı başında yapılan ekimlerin daha iyi sonuçlar verdiği kanısına varılmıştır.
Effects of Melatonin on Tomato Infected with Root-knot Nematode Meloidogyne incognita
Authors: GÖKBAYRAK Zeliha , GÖZEL Çiğdem
Published: September 2021

This study was conducted in 2020 to investigate the influence of melatonin (10, 50 and 100 µM) given in three methods (immersion, irrigation, and foliar spraying) on some physiological aspects of tomato seedlings inoculated with root-knot nematode Meloidogyne incognita [(Kofoid and White) Chitwood]. The seedlings were inoculated with 1000 second-stage juveniles of M. incognita. Dualex® optic sensor was used to in situ measure total chlorophylls, flavonols, anthocyanins contents and nitrogen balance index (NBI). Results indicated that while no significant effects were observed on chlorophyll content, melatonin ameliorated the adverse effects of M. incognita on chlorophyll depending on the concentration and mode of application. Flavonols were at the highest in the irrigated plants and the lowest in the immersed ones. NBI was affected by the method the melatonin was applied, and immersing boosted it while irrigation caused a significant decrease. Irrigation resulted in significantly higher anthocyanins compared to the other two methods. One observation was that applying melatonin in the low and medium concentrations to the soil containing nematode increased the anthocyanin content of the plant. Melatonin merits a value in developing a response against the nematode but needs further elucidation.
Analyzing the Effect of Water Body on the Thermal Environment and Comfort at Indoor and Outdoor Spaces in Tropical University Campus
Authors:   the Department of Civil Engineering and Architecture, Saga University, Japan, on leave from the Jahangirnagar University, Dhaka, Bangladesh, Reza Farhadur , Kojima Shoichi , Ando Wataru
Published: September 2021

Water bodies play a significant role in its surrounding thermal environment. Thermal comfort in university spaces is critical that affects the students’ health and performance as well as the staffs. This study investigated thermal environment and comfort near lakeside and non-lakeside tropical university spaces. Standard Effective Temperature (SET*) have been calculated using recorded air temperature, relative humidity, globe temperature, air velocity, clothing insulation and metabolic rate to evaluate the thermal comfort in outdoor and indoor spaces. The effects of weather parameters have been clearly visible on the comfort index. The calculated SET* values indicate that the outdoor thermal comfort near a lake is much closer to the standard comfort zone than non-lakeside outdoor space. In the case of indoor thermal comfort, however, slightly a different scenario has been observed. To achieve the desirable indoor thermal environment, some design considerations are recommended based on findings.
Development of a GeoGebra-Assisted Calculus Worksheet to Enhance Students’ Understanding
Authors:   Universitas Negeri Padang, Indonesia, Yerizon  , Fatimah Siti , Tasman Fridgo
Published: September 2021

The goal of this study is to develop a GeoGebra-assisted worksheet to enhance students' understanding of calculus. Many studies report that students have difficulty understanding calculus. GeoGebra provides an alternative method to overcome the difficulties associated with calculus. The Plomp development model consists of three phases: specifically, preliminary analysis, prototype development and an assessment was used in this study. The subjects of this study were 37 students. The results of this study are valid in terms of content, presentation, linguistics and graphics and practical in terms of implementation, time, ease of use and effective in terms of its potential impact on students' mathematical understanding. The GeoGebra-assisted worksheet can help students rediscover the given concept, while the use of visualization of the calculus concept can significantly enhance students’ mathematical understanding. Likewise, GeoGebra-assisted worksheets can be used to enhance students’ understanding of calculus. Teachers are suggested using GeoGebra in order to build students’ understanding on calculus subject.
Possibilities of the Ukrainian Online Platform OUM
Authors:   the Department of Computer Sciences, Dmytro Motornyi Tavria State Agrotechnological University, Melitopol, Ukraine, Sharov Sergii , Kolmakova Vira , Sharova Tetiana , Kamyshova Tetiana
Published: September 2021

Introduction of information and communication technologies in the educational process has resulted in the emergence of innovative teaching techniques, new software and technologies. One of the effective means of distance learning is mass open online courses (MOOC). The purpose of the article is to analyze the possibilities provided by the Ukrainian online platform of the Open University of Maidan (OUM), and to compare it with other Ukrainian platforms (Prometheus, EdEra) according to certain criteria. The article reveals the main advantages and disadvantages of using MOOC both for self-development and in the educational process at higher education institutions. It has been found that MOOC provide lifelong learning and implement the principles of mass involvement and openness. They also offer free online courses and generate a certificate after their successful completion. We have identified some problematic issues which cover the imperfect system of practical tasks, the need to increase users’ motivation, the language aspect, etc. The OUM online platform is primarily intended to provide civic education for community representatives and other users. We analyzed the thematic areas of the online platform and characterized them. The courses on this platform are mainly focused on the adult audience. They increase personal, communicative and civic efficiency, develop social entrepreneurship and understanding of the global content. Also, they ensure effective interaction with the authorities. During the content analysis we found that the OUM platform has specific features. In particular, it is the ability to form and graphically represent the individual educational trajectory; the platform contains exclusively Ukrainian-language content and provides an opportunity to be informed about the course progress via email. We dwelt on the possibilities of using MOOC by students, teachers and all those who are interested in self-study.
A Study of Digital Interactive Technology and Design Mode Promoting the Learners’ Metacognitive Experience in Smart Education
Authors:   Art Education Center, Northwest Polytechnic University, Xi'an, China, Liu Tao , Zheng Haihao
Published: September 2021

The effectiveness of learners’ learning in smart education is largely improved by combined with digital interactive technology and design recent years. However, most traditional smart education ignore the importance of improving learners’ metacognition experience by digital interactive technology and design. This paper focuses on the research of digital interactive technology promoting teaching reform to inspire the learners’ metacognition experience, and interactive design mode inspiring the development of smart education platform. Digital interactive technology + interactive design mode + smart education has become an important trend of smart education reform.
Ferulago pauciradiata Boiss. & Heldr. Effects of Prantschimgin Compound Isolated from the Root of the Plant on LPS-Induced Inflammation Model in the L929 Cell Line
Authors: KUTLU Zerrin , KARABULUT UZUNÇAKMAK Sevgi , KARAKAYA Songül , DELİMUSTAFAOĞLU Fatma Gül
Published: September 2021

Investigation of the effects of prantchimgin (Prn) compound isolated from the root part of the Ferulago pauciradiata (Apiaceae) plant in the lipopolysaccharide (LPS) cytotoxicity model created in the L929 cell line. L929 cell lines were applied in a 5% CO2 incubator at 37 °C, using standard cell culture procedures, LPS was applied with Prn pure substance with a final concentration of 2 µL and 1 µL after 1 hour. Following the LPS application, the MTT protocol, a colorimetric method, was applied to determine cell viability at the end of the required 24th, 48th, and 72nd hours incubation times. IC50 values were calculated as 0.28 µg/mL for Pnr and 1 µg/mL for LPS. Application of LPS to L929 cell lines caused a significant decrease in cellular index depending on time. Also, in the Prn + LPS groups, it was found that the decreased cell index significantly increased even closer to the control compared to the LPS applied group. It was found that cyctoxicity and cell damage caused by LPS applied to the L929 cell line improved after Pnr application.
The Response Surface Methodology for Depth-Dependent Chondrocyte Surface Area
Authors: ÇİÇEK Ekrem
Published: September 2021

Articular cartilage is a low-friction white connective tissue. The only cell type in articular cartilage are chondrocytes. They permit smooth articulation in cartilage. They have insufficient regenerative capacity. Response surface methodology is a very useful tool for the modelling of any processes using polynomials. This study investigated the depth-dependent chondrocyte surface area from bovine articular cartilage. Confocal microscope was utilized to image osteochondral explants. The response surface methodology was used to constitute the predictive regression model to guess chondrocyte area from confocal image of bovine articular cartilage. This methodology was employed to examine the relationships among input variables and response. The response was surface area of chondrocyte while the inputs were perimeter of chondrocyte and depth. The depth-dependent measured and calculated chondrocyte surface area was demonstrated. The response surface model was significant (p=0.001) and adequate for the prediction the chondrocyte surface area since R2 = 0.81. The chondrocyte surface area can be predicted with perimeter and depth by response surface methodology. The implementation of statistical experimental design techniques in image processing can reduce experimental runs and save experimental animals live.
Zeminlerin Doğal ve Sentetik Lifler ile Güçlendirilmesi Üzerine Bir Derleme Çalışması
Authors: YAZICI Mehmet Fatih , KESKİN Nilay
Published: September 2021

Geoteknik mühendisliği uygulamalarında zeminlerin mühendislik özelliklerinin geliştirilmesi amacıyla sıklıkla zemin güçlendirme teknikleri kullanılmaktadır. Bu amaç için son zamanlarda yeterli dayanımları, düşük maliyetleri ve kolay ulaşılabilirliklerinden dolayı doğal ve sentetik lifler, geleneksel stabilizasyon yöntemlerine alternatif bir güçlendirme tekniği olarak araştırmacıların dikkatini çekmeyi başarmıştır. Bu araştırmanın amacı; literatürde farklı türde doğal ve sentetik lifler ile zeminlerin güçlendirilmesi üzerine yayınlanmış bilimsel çalışmaların verilerini kullanarak lifin türü, fiziksel ve mekanik özellikleri, miktarı, uzunluğu ve yüzey pürüzlülüğü gibi paremetrelerin farklı türdeki zeminlerin mühendislik özellikleri üzerine etkileri hakkında bir derleme çalışması oluşturmaktır. Ayrıca bu çalışmada zemin ortamındaki suyun, doğal liflerin davranışı üzerine etkileri ve alınabilecek önlemler ile lif-zemin kompozitinin mekanik davranışı hakkında bilgiler verilmektedir.Anahtar Kelimeler: Doğal lif, sentetik lif, zemin güçlendirme
Glutamat Kaynaklı Nörotoksisite Üzerinde Pycnogenol'un Koruyucu Etkisinin Araştırılması: İn Vitro Analizi
Authors: ÇİÇEK Betül , TAGHİZADEHGHALEHJOUGHİ Ali , HACIMÜFTÜOĞLU Ahmet
Published: September 2021

Eksitatör bir nörotransmitter olan glutamatın aşırı salınımı epilepsi ve Alzheimer gibi birçok nörodejeneratif hastalığın patogenezinde yer almaktadır. Bu nedenle nöronal hücreleri glutamata bağlı toksisiteye karşı koruyan bileşiklerin araştırılması oldukça önemlidir. Pinus maritima'dan elde edilen piknogenol® içerdiği fenolik bileşikler ve flavonoidlerden dolayı güçlü antioksidan özelliğe sahiptir. Bu çalışmada Pinus maritime'den elde edilen bioflavonoid yapısında olan pignogenolün nöroprotektif etkilerini glutamat toksisitesi oluşturulan kortikal nöron kültüründe araştırmayı amaçladık. Kortikal nöron hücreleri 30 dakika süre ile 10-5 mM glutamata maruz bırakılarak glutamat eksitotoksisitesi indüklendi. Sonrasında faklı konsantrasyonlarda (10-1 - 10-5) PYC ile 24 saat boyunca inkübe edilmiştir. Hücre canlılık testi MTT yöntemi ile belirlendi. Oksidatif hasarı göstermek için total antioksidan seviyesi (TAS)- - total oksidan seviyesi (TOS) analizleri kullanılmıştır. MTT sonuçlarına göre 10-1 ve 10-2 piknogenol konsantrasyonlarının glutamat eksitotoksisitesine bağlı hücre ölümünü azalttığı görüldü. Aynı zamanda TAS-TOS sonuçları MTT sonuçları ile korelasyon saptandı. Bu çalışma sonuçlarına göre piknogenolün glutamat eksitotoksisitesine karşı teropatik ajan olarak kullanılabileceği düşünülmüştür.