bluuebunny/crossref_metadata_2025 huggingface dataset:
AHP and fuzzy logic geospatial approach for forest fire vulnerable zones
Authors: Shatnawi Nawras
Published: September 2022

Fires are devastating risky events in forests, having a negative effect on resources, biodiversity, economics, animal life, and putting people in danger. The goal of this study is to use geospatial techniques to identify areas in Jordan that are at risk of forest fires. The research area extends 50 kilometers north and 15 kilometers east from the Dead Sea. The forest fire risk zones map was developed using six factors: land cover class, aspect, proximity to settlements, elevation, slope, and proximity to roads. All of the factors have been selected based on their fire sensitivity or capacity to cause fire. In this study, a Turkish model with fuzzy logic and Analytical hierarchy analysis (AHP) was utilized to classify the area into five categories of risk ranging from very low to very high. According to the findings, approximately 12.12% of the study area is classified as very low risk, 25.54 % is classified as medium risk, while 12.84% is classified as very high risk. Over the last ten years, the map has been confirmed by prior fire occurrences using data from civil defense archives. This conclusion was very useful in gaining an understanding of the geographical distribution of fire-vulnerable zones. The research found that the GIS approach combined with AHP and fuzzy logic is a useful tool for estimating such kinds of maps.
Peru-China international trade and its effect on inclusive economic growth in Peru 2000-2019
Authors: Angulo-Bustinza Harold D. , Arce-Larrea Glenn R. , Calderon-Contreras Valentín J.
Published: September 2022

From 2000 to 2019, trade between the People's Republic of China and the Republic of Peru grew at an average annual rate of 22%, however, income and wealth inequality in Peru remained the same. The aim of this study is to understand the effect of trade between Peru and China on the inclusive economic growth of Peru from 2000 to 2019. The method used was the correlation of variables, and a linear regression between Peru and China trade and several indicators of inclusive economic growth in the Peruvian economy was performed using the Ordinary Least Squares model. The results suggest that there is sufficient statistical evidence to support that inclusive economic growth may depend on increased trade between Peru and China; the study show that if trade growth between Peru and China fluctuates by $1 million per year, labor income will increase by $10.3 per capita in the Economically Active Population (EAP). Moreover, for every 1% increase in trade between Peru and China, GDP per capita increases by 0.1057% and labor productivity increases by 0.0681740%. The variables poverty, vulnerable employment, GINI index and life expectancy at birth were not significant factors.
Simulation and modeling of human decision-making process through reinforcement learning based computational model involving past experiences
Authors: Gupta Nimisha , Ahirwal Mitul Kumar , Atulkar Mithilesh
Published: September 2022

Experience plays a vital role in the decision-making (DM) process. In this paper simulation, modeling, and analysis of past experience over DM has been done using the Iowa gambling task (IGT). The Human DM process is very complex and difficult to model through computational methods because it is a subjective type of process and varies person-to-person. Therefore, this study is an attempt to simulate a DM model similar to the human DM process. For this collection of real data was done and was provided as input to the developed eight Reinforcement Learning (RL) models. The result shows that the performance of the model based on Prospect Utility (PU) learned with Decay Reinforcement Rule (DRI) and Trial Dependency Choice (TDC) is better as compared to other models. It is observed from the analysis of data and also validated that simulation and models output that the experienced group performs better than inexperienced.
RP - HPLC Method Development and Validation for Simultaneous Estimation of Pyrantel Pamoate, Praziquantel, Febantel in Tablet
Authors: Dineshkumar Patel Bhoomi , Mishra Anamika , Chaudhary Ankit
Published: September 2022

A simple, rapid, economical, precise and accurate RP-HPLC method for simultaneous estimation of praziquantel, pyrental pamoate and febantel in their combined dosage form has been developed. A validated RP-HPLC method for simultaneous estimation of pyrental pamoate, praziquantel, febantel in tablet dosage form has been developed. The separation was achieved by C18 column (250 x 4.6mm, 5µm particle size) with mobile phase of Buffer: ACN (60:40% v/v) pH 3.0, at a flowrate of 1mL/min and effluent was monitored at 240nm using PDA detector. Retention time of praziqunatel, pyrental pamoate and febantel was found to be 2.587 min, 5.970 min and 8.401 min respectively. The method has been validated for linearity, accuracy, precision, specificity, limit of detection and limit of quanitzation. Linearity was found in the range of 6.25-18.75 µg/ml, 18-54 µg/ml and 18.75-56.25 µg/ml for praziquantel, pyrental pamoate and febantel. The recoveries for praziquantel, pyrental pamoate and febantel were found to be 99.76 ± 0.211%, 99.77 ± 0.490% and 99.61± 0.241 respectively in tablet. The percentage assay of three drugs were found to be 96.82%,97.66% and 96.92% for Praziquantel, Pyrental pamoate and Febantel respectively. Developed method was found to be new, accurate, precise and robust for simultaneous estimation of praziquantel, pyrental pamoate and febantel in tablet dosage form. The proposed method enables rapid quantification and simultaneous analysis of three drugs from commercial formulations without any excipients interference.
Case report on typhoid fever
Authors:   Department of Microbiology, SS Subharti Medical College, RBB Subharti University, Dehradun, Uttrakhand, India., Verma Gaurav , Rajgopal Swapna Kurup ,   HOD, Department of Microbiology, KKBM Subharti Hospital, Dehradun, RBB Subharti University, Dehradun, Uttrakhand, India., Kashyap Priyanka ,   Department of Microbiology, SS Subharti Medical College, RBB Subharti University, Dehradun, Uttrakhand, India., Sharma Urvashi ,   Department of Microbiology, SS Subharti Medical College, RBB Subharti University, Dehradun, Uttrakhand, India.
Published: September 2022

An Eight-year-old boy with high grade fever, abdominal pain and vomiting suspected for typhoid and diagnose by serological test (rapid card test), urine analysis and blood culture were also performed. Rapid card test is very helpful for the detection of IgG and IgM antibodies present in the body in 15-30 minutes of time. With rapid card test and blood culture the patient was diagnosed with typhoid fever. The Ceftriaxone antibiotic was given to patient intravenously for 5 days and the patient recovered. Keywords: enteric fever; typhoid fever; blood culture; serology for typhoid.
HE4 elevated levels correlated with breast cancer progression
Authors:   Biochemistry Labs, Sherbin Central Hospital, Ad Daqahliyah, Ministry of Health, Egypt, A Abdelrazek Mohamed , A Barakat Lamiaa ,   Department of Chemistry, Faculty of Science, Port Said University, Egypt., Nageb Ahmed ,   Department of Chemistry, Faculty of Science, Port Said University, Egypt., Elbaz Rizk ,   Genetics Unit, Faculty of Medicine, Mansoura University, Egypt., Abouzid Amr ,   Department of Surgical Oncology, Oncology Centre, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Published: September 2022

Background: Despite several, there were many Breast Cancer (BC)- related deaths around the world. Searching for new analytical tools for BC detection at early stages is widely demanded. Aim: We aimed to evaluate Human Epididymal Protein 4 (HE4) clinical value in BC development and progression. Methods: HE4 serum levels were determined by ELISA in females with BC (n=120), benign breast disease (n=40) and healthy women (n=40). Receiver operating characteristic curve was applied for evaluation HE4 diagnostic power. Results: In BC patients, HE4 [5 (2-11.9) vs. 3.1 (1.8-5.4) and 1 (1- 3.5); P=0.022] was significantly higher than that in benign and healthy females, respectively. Compared to CEA and CA-15.3, it had superior diagnostic ability (AUC=0.783; P<0.0001; 73.3% sensitivity; 63.7% specificity). This ability increase when comparing BC patients to only healthy controls (AUC=0.862; 73.3% sensitivity; 77.5% specificity). Elevated HE4 levels were associated disease progression including multiple lesions, late stages, high grades, large size, lymph node invasion and non-luminal molecular subtypes. Spearman correlation analysis revealed that HE4 high levels significantly (P<0.05) correlated with tumor stage, histological grade and tumor size. Conclusions: HE4 is inexpensive, rapid, easy to perform and reliably BC biomarker. Moreover, its association with disease severity may support its potential role as prognostic BC marker.
Nonpuerperal mastitis associated with prolactinoma: Case report
Authors:   Xiang’an Hospital of Xiamen University, The Department of Breast-Thyroid Surgery, China., Tang Minhui Tang , Huang Wenhe ,   Xiang’an Hospital of Xiamen University, The Department of Breast-Thyroid Surgery, China.
Published: September 2022

Nonpuerperal mastitis (NPM) is characterized by chronic nonspecific inflammation, complex pathological types, and unclear causes. Prolactin seems to play an important role in the occurrence and development of NPM. This study reports two cases of mastitis with prolactinoma. While treating mastitis, active treatment of prolactinoma and reduction of prolactin levels have achieved good curative effects. Keywords: non-puerperal mastitis; prolactinoma; hyperprolactinemia.
Two cases of anomalous origin of left coronary artery from the pulmonary artery
Authors:   Taizhou People’s Hospital, Taizhou, Jiangsu, 225300 China, Juan Zhao , Chunbo Zou ,   Taizhou People’s Hospital, Taizhou, Jiangsu, 225300 China
Published: September 2022

Coronary artery originating from pulmonary artery is a rare congenital vascular malformation, which generally presents corresponding clinical symptoms with the growth of patients’ age. Coronary CTA and angiography are important methods for diagnosis of this disease, and provide evidence for treatment strategies of patients. Keywords: bicardiovascular malformations; coronary arteries; coronary cta.
Unmasking hereditary hemochromatosis with CFTR modulator therapy
Authors:   University of Oklahoma School of Community Medicine, Department of Pediatrics, Tulsa, OK, USA., Wong Richard , Roberts Abigail ,   University of Oklahoma School of Community Medicine, Department of Pediatrics, Tulsa, OK, USA., Condren Michelle ,   University of Oklahoma School of Community Medicine, Department of Pediatrics, Tulsa, OK, USA.
Published: September 2022

Cystic Fibrosis (CF) is a genetic condition affecting the ability to excrete chloride, resulting in multi-system organ damage. Liver disease is one co-morbidity that affects 20-40% of people with CF. This case describes a 16-year-old male with CF (F508Del and Q493X mutations) who was started one lexacaftor/tezacaftor/ifacaftortriple CF Transmembrane Regulator (CFTR) modulator therapy. Prior to starting treatment, it was noted that he had transaminitis (AST 69, ALT 120, Total bilirubin 0.4). His liver enzymes continued to increase with therapy and at week 8 of treatment he complained of abdominal pain, body aches, and fatigue warranting further evaluation. At that time, AST and ALT were elevated at 5- and 13-times the Upper Limits of Normal (ULN) and creatinine kinase was elevated at 12-times ULN. A dose reduction led to a decrease in AST and ALT to 2 and 4-times ULN, but total and direct bilirubin increased to 2.2 mg/dl and 0.5 mg/dl, warranting a liver ultrasound and biopsy. Pathology showed fatty liver and hepatocyte iron deposition, but no indications of cirrhosis. Iron studies and genetic testing confirmed a diagnosis of HH (Homozygous HIS63ASP gene mutation). After stopping triple CFTR modulator therapy, AST and ALT continued to rise, prompting further evaluation by hepatology and hematology. Upon discontinuation of drug therapy, his lung function dropped significantly back to baseline values and respiratory symptoms returned. Discussion: Hereditary hemochromatosis gene mutations have been shown to have a gene modulating impact on CFTR gene mutations that can affect CF disease phenotype, which negatively affects pulmonary function and gastrointestinal disease. In this case, the introduction of a new medication instigated further work-up leading to the discovery of a potential alternative cause of hepatic dysfunction while attempting to optimize medications to sustain improvements in pulmonary function. Although elevated hepatic transaminases can be expected from CF and CFTR modulator therapy, further investigation may be indicated in patients with persistent elevations despite medication adjustments. This workup may lead to important considerations in balancing liver function with lung function. Keywords: cystic fibrosis; elexacaftor; tezacaftor; ivacaftor; liver transaminases; hereditary hemochromatosis.
Evaluation of IL-1β and TNF-α level in endometrial flush in patients with recurrent implantation failure
Authors:   Human Assisted Reproduction Department of 1st Gynecology Clinic, “Iuliu Hatieganu” University of Medicine and Pharmacy ClujNapoca, Romania., Harșa Radu , Pintea Irena ,   Allergy and Immunology Department, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Romania., Micu Romeo ,   Human Assisted Reproduction Department of 1st Gynecology Clinic, “Iuliu Hatieganu” University of Medicine and Pharmacy ClujNapoca, Romania., Surcel Mihai ,   Human Assisted Reproduction Department of 1st Gynecology Clinic, “Iuliu Hatieganu” University of Medicine and Pharmacy ClujNapoca, Romania., Stamatian Florin ,   Human Assisted Reproduction Department of 1st Gynecology Clinic, “Iuliu Hatieganu” University of Medicine and Pharmacy ClujNapoca, Romania.
Published: September 2022

Infertility is defined as the inability to conceive within a year of regular unprotected intercourse affecting one in six couples. The most common causes of infertility are ovulatory dysfunction, male factor infertility, and tubal disease [1]. Unexplained Infertility (UI) and Recurrent Implantation Failure (RIF) are diagnoses based on failed pregnancy attempts with current infertility treatment options. UI is diagnosed when testing is inconclusive and RIF is diagnosed after three failed In Vitro Fertilization (IVF) cycles. UI is the absence of conception despite 12 months of unprotected intercourse, not explained by anovulation, poor sperm quality, tubal pathology or other known cause of infertility. RIF is defined by three failed IVF cycles in which one or two high-quality embryos are transferred in each cycle or by two failures in oocyte donor recipients after the transfer of good quality embryos [1]. UI is a common cause of infertility affecting 10-30% of infertile couples [2], while RIF is present in around 10% of in vitro fertilization (IVF) cycles [3].
Unusual case of pulmonary artery dissection presenting as an exacerbation of COPD
Authors:   Darul sehat Hospital, St-19, KDA Scheme, Abul Asar Hafeez Jalandhari Rd, Block 15 Gulistan-e-Johar, Karachi City, Sindh, Post code 75290, Pakistan., Najeeb Ullah Khan Muhammad , Hamdallah Hanady ,   Senior Lecturer, Chester Medical School, University of Chester, Bache Hall, Chester, CH2 1BR, UK., Ponnuswamy Aravind ,   Consultant Physician, GIM and Respiratory Medicine, Countess of Chester Hospital NHS Trust, Countess of Chester Health Park, Liverpool Road CH2 1UL, UK.
Published: September 2022

A 61-year-old male with a background of COPD and non-small cell lung carcinoma diagnosed ten years prior to presentation was seen with chest symptoms. He was an ex-smoker and presented with exertional dyspnoea, chest pain, cough, and wheeze. He had been on chemoradiotherapy for his cancer. The patient was seen in the clinic and admitted intermittently due to shortness of breath, pleural effusion, and exacerbations of COPD. He had undergone CT, MRI, PET scan and missed the PAD diagnosis due to post-chemo-radiotherapy effects. The patient was diagnosed with PAD incidentally through CTPA. The patient was treated medically throughout for Pulmonary hypertension. He was not fit for any surgical intervention and passed away approximately 21 months after diagnosis of Pulmonary artery dissection. The case highlight survival of months in a case of Pulmonary artery dissection without any intervention therapy, including surgery
Effective hemostasis by use of hemospray in a case of severe bleeding in the jejunum
Authors:   Department of Gastroenterology, Skåne University Hospital, Lund University, Malmö, Sweden, Johansson Gabriele Wurm , Nemeth Artur ,   Department of Gastroenterology, Skåne University Hospital, Lund University, Malmö, Sweden, Santen Stefan ,   Department of Surgery, Skåne University Hospital, Lund University, Malmö, Sweden., Weiber Håkan ,   Department of Surgery, Skåne University Hospital, Lund University, Malmö, Sweden., Thorlacius Henrik ,   Department of Surgery, Skåne University Hospital, Lund University, Malmö, Sweden., Ljungberg Otto ,   Department of Pathology, Skåne University Hospital, Lund University, Malmö, Sweden., Toth Ervin ,   Department of Gastroenterology, Skåne University Hospital, Lund University, Malmö, Sweden.
Published: September 2022

Gastrointestinal (GI) bleeding remains one the most common life-threatening emergencies associated with high morbidity and mortality and requires rapid and effective endoscopic hemostasis. Despite several available endoscopic hemostatic methods (injection therapy, mechanical and thermal therapy), the treatment of small bowel bleeding is still challenging, and successful hemostasis can be difficult to achieve. One of the novel topical hemostatic agents (Hemospray; Cook Medical, Winston-Salem, NC) was approved for the management of non-variceal upper GI bleeding, and clinical efficacy was shown for GI bleeding due to peptic ulcer, malignancy, gastric variceal hemorrhage, antithrombotic therapy, and lower GI bleeding [1- 5].
Isolated tricuspid valve disease in antiphospholipid syndrome
Authors:   Department of Medicine, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Israel., Edri Ron , Ishay Yuval ,   Allergy and Clinical Immunology Unit, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Israel., Rubin Limor ,   Institute of Gastroenterology and Hepatology, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Israel., Kharouf Fadi ,   Rheumatology Unit, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Israel.
Published: September 2022

We report the case of a 27-year-old male, presenting with dyspnea and chest pain. Radiographic and echocardiographic evaluations revealed bilateral segmental pulmonary embolism, left lower extremity deep vein thrombosis, and isolated tricuspid valve endocarditis. Microbiologic and serologic tests ruled out an infectious etiology and supported a diagnosis of nonbacterial thrombotic endocarditis as a manifestation of a newly diagnosed antiphospholipid syndrome. We discuss the clinical presentation, diagnostic evaluations, treatment, and clinical outcome.
Twin-Twin Transfusion Syndrome (TTTS) in dichorionic-diamnionic twin pregnancy: A case report
Authors:   Obstetrics Department, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 450052., Li Genxia , Chu Shuhui ,   Obstetrics Department, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 450052., Zhang Linlin ,   Department of clinical Laboratory, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 450052, Feng Shuo ,   Obstetrics Department, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 450052., Li Hezhou ,   The Ultrasound Department, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 450052., Dong Li ,   The Ultrasound Department, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 450052., Hao Zhiwei ,   The Pathology Department, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 450052., Niu Yanxia ,   Obstetrics Department, Luan Chuan Maternal and Child Health Hospital, Luoyang, China, 471500., Yu Haiyang ,   Department of clinical Laboratory, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 450052, Chen Kang ,   Departments of Obstetrics and Gynecology, Oncology, Biochemistry, Microbiology and Immunology, Wayne State University, Detroit, MI 48201, USA.
Published: September 2022

Twin-to-Twin Transfusion Syndrome (TTTS) is a serious complication of twin pregnancy, which develops in approximately 10 to 15 percent of monochorionic twin pregnancies while it is very rare in dichorionic pregnancies. At present, fetal laser surgery has become the preferred treatment for stage II to IV TTTS. It has been reported that fetal laser therapy after early diagnosis of TTTS can improve neonatal outcome. From May 2018 to December 2021, there are a total of 140 cases which underwent fetoscopic laser surgery in the Third Affiliated Hospital of Zhengzhou University. Among them, one case of twin-twin transfusion syndrome was dichorionic twins. The patient with dichorionic-diamnionic twin pregnancy was diagnosed with TTTS Stage II at 23 weeks and 4 days of Gestational Age (GA). After fetoscopic laser surgery and bipolar coagulation, the patient delivered vaginally two viable male infants at 31 weeks GA. Follow-up showed that the two infants survived. Keywords: TTTS; dichorionic twins; fetoscopic; placenta
Iatrogenic aortocaval shunt treated by stent graft placement into the inferior vena cava
Authors:   Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, 14021 Prague 4, Czech Republic., JH Peregrin , D Vedlich ,   Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, 14021 Prague 4, Czech Republic., J Šochman ,   Department of Cardiology, Institute for Clinical and Experimental Medicine, 14021 Prague 4, Czech Republic.
Published: September 2022

Fifty six year old male sustained an injury to the abdominal aorta during his 1992 lumbar disc surgery with subsequent aortocaval shunt formation. In order to close the shunt, his abdominal aorta and both common iliac arteries were ligated and bilateral aortoiliac bypass was implanted. Postoperatively the patient remained asymptomatic for several years. Subsequently he developed arterial hypertension, his exercise capacity diminished and he complained of exertional dyspnea. Intraarterial DSA demonstrated filling of the occluded aortic segment from intercostal and lumbar arteries as well and a shunt between this segment and the inferior vena cava. The hemodynamic significance of the shunt was confirmed using catheterization. Attempted reduction of the shunt flow by intercostal arteries embolization was not successful. We were successful in closing the fistula using a custom-made stent graft. CTA performed 18 years after the procedure confirmed absence of the shunt and patent inferior vena cava. The patient is now asymptomatic 23 years after the original surgery.
A case of Mounier-Kuhn syndrome in a geriatric patient
Authors:   ntensive Rehabilitation Unit, S’Anna Institute, 88900 Crotone, Italy., Pugliese Maria Elena , Battaglia Riccardo ,   ntensive Rehabilitation Unit, S’Anna Institute, 88900 Crotone, Italy., Coschignano Francesco ,   ntensive Rehabilitation Unit, S’Anna Institute, 88900 Crotone, Italy.
Published: September 2022

Mounier-Kuhn syndrome, or tracheobronchomegaly, is a rare clinical and radiologic condition characterized by marked tracheobronchial dilation and recurrent lower respiratory tract infections. The syndrome was first described by Mounier-Kuhn in 1932, and few cases have been reported in the medical literature [1]. The clinical presentation varies widely, from asymptomatic disease with preserved lung functions to recurrent chest infections, exertional dyspnoea to even respiratory failure in severe cases. Diagnosis is often made by using CT, through which abnormally large air passages are detected. In adults, the diagnostic criteria are diameters of the trachea >30 mm, right main bronchus >20 mm and of the left main bronchus >18 mm [2-4]. Upon pulmonary function testing, decreased bronchial flow speed, increased tidal volume, and dead spaces may be observed. Bronchoscopy can detect the pathologic processes that affect the tracheobronchial structures. Connective-tissue diseases, ataxia-telangiectasia, ankylosing spondylitis, EhlersDanlos syndrome, Marfan syndrome, Kenny-Caffey syndrome, Brachmann-de Lange syndrome, and cutis laxa (elastolysis) are also associated with secondary tracheobronchial enlargement [2-5]. All these conditions should be considered in the differential diagnosis.
Analysis of characteristics of workers with occupational benzene poisoning in Jiangsu province, 2006-2018
Authors:   School of Public Health, Southeast University, Nanjing, Jiangsu, China, Guangzhi Yang , Boshen Wang ,   School of Public Health, Southeast University, Nanjing, Jiangsu, China, Mengyao Chen ,   School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China., Hao Chen ,   School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China., Lei Han ,   Department of Prevention and Control for Occupational Disease, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu, China., Baoli Zhu ,   School of Public Health, Southeast University, Nanjing, Jiangsu, China
Published: September 2022

Objective: To investigate the characteristics of workers with occupational benzene poisoning in Jiangsu Province during 2006-2018, find out the susceptible population of occupational benzene poisoning and provide some evidence for establishing some exposure standards for workers. Methods: Questionnaire is the tool that we adopt to collect basic information of workers. Benzene detector is applied to detect the concentration of benzene in the working environments. Statistical description and analysis was conducted to analyze the prevalence of occupational benzene poisoning in Jiangsu Province during 2006-2018. Results: The number of cases of occupational benzene poisoning in these years was 145, and 28 of them were diagnosed with benzene induced leukemia; the patients mainly worked in manufacturing industry (89.7%); most of cases were distributed in small factories (43.4%) and private companies (46.2%). Male workers took a major part in the cases of acute benzene poisoning(80%)while female workers had a higher proportion of the chronic benzene poisoning (65%). Most cases were distributed in the 30-49 age group (80%). There was no evident differences among these seniority groups, most of the cases were in the working age of 1-19 years old (82.9%); concentration of benzene of chronic benzene poisoning workers were mostly under 0.6mg/m³ (40%). Conclusions: The departments of occupational disease prevention should heighten the benzene surveillance of small-scale private companies in manufacturing industry, regular physical examination and health education should be conducted in the workers of low concentration of benzene exposure, safety protection measures should be taken to reduce the incidence of occupational poisoning. Keywords: occupational disease; occupational benzene poisoning; benzene induced leukemia
Role of magnetic resonance imaging in the pre‐surgical planning of perianal hidradenitis suppurativa, complicated by anal fistulae: A case report and review of the literature
Authors:   Radiology Unit, Department of Radiology, Pugliese-Ciaccio Hospital, Catanzaro, Italy, Arcuri Pier Paolo , Comito Laura ,   Radiology Unit, Department of Experimental and Clinical Medicine, “Magna Graecia” University, Catanzaro, Italy, Vavalà Barbara ,   Radiology Unit, Department of Radiology, Pugliese-Ciaccio Hospital, Catanzaro, Italy, Laganà Domenico ,   Radiology Unit, Department of Experimental and Clinical Medicine, “Magna Graecia” University, Catanzaro, Italy
Published: September 2022

Hidradenitis Suppurativa (HS) is a chronic inflammatory disease of the skin starting from the apocrine glands and mainly involving the axilla, perineum and perianal area. It is clinically defined by the onset of painful subcutaneous nodularities, associated with signs of local inflammation, whose progression proceeds towards the definition of true subcutaneous abscess collections from which fistulous pathways branch off. These lesions result in severe fibro-cicatricial deformities. The diagnosis of HS, which is basically clinical, is followed, due to the recurrent/relapsed nature of the disease, by a difficult therapeutic management, which makes use of different treatments depending on the severity of the pathological picture, ranging from topical or systemic medical therapy to surgical excision. Imaging examinations, although not specific enough in the diagnosis of HS, are essential to define the loco-regional extension of the disease and to exclude possible alternative diagnoses. In particular, MRI plays a key role in the study of HS with anogenital localization, both for the recognition of lesions in the active phase and for the assessment of the local extension of the disease, in particular in adequately demonstrating the entire course of the fistulas and the relationships with the neighboring anatomical structures. This allows the optimization of its treatment, in order to reduce disease recurrence. The case presented by us describes the MRI characteristics in a rare case of HS, complicated by anal fistulae.
Spiderweb omentum – A previously unknown surgical finding in ovarian cancer
Authors:   All India Institute of Medical Sciences, New Delhi, India, Ray Mukurdipi , Chhebbi Madiwalesh ,   All India Institute of Medical Sciences, New Delhi, India
Published: September 2022

Carcinoma ovary is the most lethal gynecological malignancy and thereby, leading cause of death worldwide. Most common histopathology of ovarian cancer is high-grade serous carcinoma. More than 75% patients present at advanced stages, FIGO stage III onwards. The response of chemotherapy in patients is variable and the surgical finding of the state of omentum following chemotherapy has not been described specifically in literature. Here we presented a case of carcinoma ovary whose omental caking totally dissolved after chemotherapy leaving behind only the vasculature resembling a spiderweb. Though the treatment policy was the same. Keywords: Carcinoma ovary; Neoadjuvant Chemotherapy; Omental caking; Spiderweb omentum.
Intestinal perforation after extracorporeal lithotripsy; Possibility of nonoperative management
Authors:   Regional University Hospital of Malaga, Malaga, Spain., Galeano Pablo Fernández , Silva Cristina Rodriguez ,   Regional University Hospital of Malaga, Malaga, Spain., Gutiérrez Delgado María del Pilar ,   Regional University Hospital of Malaga, Malaga, Spain., Rodriguez Rosa Perez ,   Regional University Hospital of Malaga, Malaga, Spain., Santoyo Julio ,   Regional University Hospital of Malaga, Malaga, Spain.
Published: September 2022

Extracorporeal Shock wave Lithotripsy (ESWL) has proved to be effective safe and nowadays is the preferred method of treatment of over 90% of upper urinary tract stones [1,2]. Nevertheless, ESWL is not devoid of complications. Although the majorities are trivial and transient, serious complications could occur but are extremely rare and only very few have been reported in the literature [3]. We report a case of small intestinal perforation following ESWL. The case is striking because we decided to carry out a non-operative management, which in this case turned out to be successful. We are not aware of another such case in the English-language literature.
Anton syndrome due to bilateral posterior cerebral artery stroke with polyneuropathy in a patient with uncontrolled diabetes mellitus
Authors:   Resident, Jagannath Gupta Institute of Medical Science, Kolkata, India., Basu Subhadeep , Ghosh Suprotim ,   Resident, Jagannath Gupta Institute of Medical Science, Kolkata, India., Choudhury Krishnendu ,   Assistant Professor and Neurologist, Jagannath Gupta Institute of Medical Science, Kolkata, India., Sarkar Swapan ,   Associate Professor, Department of Medicine and Neurology, Jagannath Gupta Institute of Medical Science, Kolkata. India.
Published: September 2022

Associate Professor, Department of Medicine and Neurology, Jagannath Gupta Institute of Medical Science, Kolkata. India.
Unusual cause of dyspnea and hemoptysis in a healthy female
Authors:   Division of Thoracic and Esophageal Surgery, Department of Surgery, University Hospitals CMC and Case Western Reserve SOM, Cleveland, OH, USA., A Bassiri , A Badrinathan ,   Division of Thoracic and Esophageal Surgery, Department of Surgery, University Hospitals CMC and Case Western Reserve SOM, Cleveland, OH, USA., CE Alvarado ,   Division of Thoracic and Esophageal Surgery, Department of Surgery, University Hospitals CMC and Case Western Reserve SOM, Cleveland, OH, USA., CW Towe ,   Division of Thoracic and Esophageal Surgery, Department of Surgery, University Hospitals CMC and Case Western Reserve SOM, Cleveland, OH, USA.
Published: September 2022

Rare congenital malformation can lead to the aberrant communication between systemic arterial circulation with pulmonary venous circulation which can range from sequestration to arteriovenous fistulas. We describe a 24 year old female with no significant medical history presenting with dyspnea and hemoptysis. On Computerized Tomography (CT) and angiogram found to have an aberrant vessel branching from celiac axis supplying the right lower lobe and draining into the inferior pulmonary vein with evidence of vascular steal. Due to the size of the vessel, decision was made to forego coil embolization and underwent Video-Assisted Thoracoscopic Surgery (VATS) ligation of the aberrant vessel. She had an uncomplicated operative course and post operatively had resolution of her symptoms. This report demonstrates a rare anatomical congenital vascular malformation causing hemoptysis and resolution of symptoms after ligation of the aberrant blood vessel. Keywords: pulmonary arteriovenous fistula; vats; hemoptysis.
A case report and review of the literature on Von Recklinghausen’s disease complicated with cervicofacial plexiform neurofibromas
Authors:   Radiology Department, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco, Sahli Hind , El Mandour Jihane ,   Radiology Department, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco, En-nouali Hassan ,   Radiology Department, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco, El Fenni Jamal ,   Radiology Department, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco, En-nafaa Issam ,   Radiology Department, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco
Published: September 2022

Neurofibromatosis type I, also known as Von Recklinghausen disease, is an autosomal dominant genodermatosis caused by a mutation in the NF1 gene on chromosome 17q11.2. It is characterized by a wide range of clinical signs and symptoms comprising macules of café-au-lait and tumours of the nerve sheath [1]. Neurofibromas make up 90% of all instances and plexiform tumors are less common [2]. Plexiform neurofibromas are largely pathognomonic for NF1, appearing as a “bag of worms” with diffuse involvement along a nerve segment and its branches [3]. The eyelids, trunk, and limbs are the most common sites for plexiform neurofibromas. It’s unusual to find localization in the cervico-facial region [4]. We present the case of a 20-year-old female patient who had been followed for von Recklinghausen’s disease from childhood and complained of a growing cervicofacial lump.
Anxiety as neuropsychological symptom of aphasia
Authors:   Private Practice of Neurology, Neuroceuta, (Virgen de Africa Clinic), Ceuta, Spain., Altable Marcos , Raigal Pilar ,   Complutense University of Madrid, Madrid, Spain., de la Serna Juan Moisés ,   Department of Education, International University of La Rioja (UNIR), Madrid, Spain, Mena Sara ,   Private Practice of Neuropsychology, Neuredy, Ceuta, Spain.
Published: September 2022

Aphasia causes a significant limitation on the person who suffers it since communication is essential for the human being. Among the behavioural changes observed in people with aphasia, we can highlight impulsive responses, rejection and states of intense anxiety [21]. People with aphasia face daily challenges from impaired communication skills. This can be a source of stress and anxiety, as well as other neuropsychological problems (depression, behavioural changes, aggressiveness / apathy, among others).
The Impact of FDI Inflows and ICT Development towards Economic Growth: Evidence for China and Malaysia
Authors: Norehan Muhammad Aiman Haziq , Ridzuan Abdul Rahim , Ismail Shafinar , Md Razak Mohamad Idham , Shaari Mohd Shahidan
Published: September 2022

This paper examines whether there is a long-run relationship between foreign direct investment (FDI) inflows, ICT development and economic growth in China and Malaysia. We use a newly developed cointegration test, the autoregressive distributed lag (ARDL), to examine this long-run relationship by employing annual data from 1980 to 2017. The study results show that ICT has a positive relationship with economic growth in China while negative in Malaysia. Capital and labour were found significantly influence economic growth in China and Malaysia. FDI inflows and human capital failed to influence economic growth in China, but human capital significantly influenced Malaysia. The findings are important for formulating policies by recommending mandatory policies related to FDI inflows, human capital and labour to achieve long-term and sustainable development in China and Malaysia.
Dummy Subjects in English: A Grammatical Analysis
Authors: Hussein Aqeel Kadhom , Al-Hussein Aqeel Mohsin Abbood
Published: September 2022

In fact, any sentence in the language that has a subject is the one who does the action. The verb, the doer of a language, tells us who has already done the action that was described by the action as the initial element that begins a sentence grammatically. There are two types of subjects in the English language, which is the language in question: actual subject, which performs the action, and dummy subject, which fills the position of the real subject and has a grammatical function but no semantic significance.The study focuses on the syntactic analysis of dummy, expletive, or empty subjects that lack the qualities of real people. Dummy subjects are also known as the sentence's doer, and they are just one of several issues that weaken the phrase by making it unclear or opaque. The study starts with a look at the concept of the subject in general, then moves on to dummy subjects, which are subjects that just fill the subject's position to provide a grammatical purpose without any semantic function. The study looks at the two dummy subjects "it" and "there" in an English sentence and how they may appear with different verbs. The incorrect usage of the dummy subject "there" with the singular verb "be" is criticized in the study.
Türkiye’nin Dış Ticaret ve İklim Değişikliği Politikaları: SWOT Analizi Yöntemi
Authors: ÇAĞATAY Bilge
Published: September 2022

Küresel iklim değişikliği yirmi birinci yüzyıla damgasını vuran ulusal ve uluslararası yeni düzenlemeler gerektiren temel tartışma alanı haline gelmiştir. Küresel iklim değişikliğinin tüm doğayı ve canlıları etkileyecek hale gelmesiyle mevcut kurulu sosyal, ekonomik ve politik düzenin devam ettirilme zorlukları ortaya çıkmıştır. Bu bağlamda, çalışmada küresel iklim değişikliğinin Türkiye’deki dış ticaret ve üretim üzerindeki etkilerinin tartışılması hedeflenmektedir. Zira Türkiye kalkınma ve sanayileşme yolunda ilerleyen bir ekonomi olarak küresel iklim değişikliği ve bu değişimin politika dönüşümüne maruz kalmaktadır. Türkiye’nin iklim değişikliği ve dış ticarette orta ve uzun vadeli tahminlere dayalı konumunun ne olacağı ana araştırma sorusudur. Çalışmada Türkiye’deki değişimin yönünün tayin edilebilmesi amacıyla nitel bir çalışma yöntemi olarak SWOT analizi kullanılmıştır. SWOT analizi ile Türkiye’nin iklim değişikliği ve uluslararası ticaret politikalarında temel belirleyici değişkenler olarak içsel ve dışsal faktörler ele alınmıştır. Bahsi geçen bu faktörler analizin yapısı gereği güçlü yönler, zayıf yönler, fırsatlar ve tehditler olarak dörde ayrılmıştır. Sonuç kısmında ise elde edilen bulgular ile Türkiye’nin orta ve uzun vadeli planlarında yer alması gereken politika önerileri sunulmaktadır.
Mustafa Kemal Atatürk'ün Liderlik Tarzının Sürdürülebilir Liderlik Açısından Değerlendirilmesi
Authors: MISIRDALI YANGİL Fulya , ÖZTÜRK BAŞPINAR Nuran
Published: September 2022

Son on beş yıldır birçok araştırmada ve alanda incelenmeye devam eden ve çok boyutlu bir kavram olan sürdürülebilirlik, geleceğin yaşam koşullarının gasp edilmemesi için bugüne odaklanılmasını temel almaktadır. Ancak bu gelecek bakış açısının hâkim olabilmesi ve bunun istenilen geleceğin oluşturabilmesi için sürdürülebilirlik eylemlerini yürütebilecek nitelikte liderlere ihtiyaç vardır. Bu liderler sürdürülebilir lider olarak adlandırılmakta ve yaşadıkları dönemin sosyal, kültürel, ekonomik ve çevresel sorunlarını gören, anlayan ve bunlara ilişkin kaygılarıyla beraber çevrelerinde yer alan bireylere vizyon çizen, onları organize eden kişiler olarak tanımlanmaktadırlar.Türkiye Cumhuriyeti'ne yön veren, halkın sosyal, kültürel, ekonomik ve çevresel sorunlarını çözmek adına harekete geçerek cumhuriyeti kuran Mustafa Kemal Atatürk bu liderlik tarzının önemli örneklerinden biridir. Atatürk askeri başarıları, devlet adamlığı, reformcu özellikleri ve liderliği ile birçok araştırmada incelenmiştir. Bu çalışmada ise Atatürk’ün liderliğinin sürdürülebilir liderlik çerçevesinde değerlendirilmesi amaçlanmıştır. Çalışmanın amacı doğrultusunda Atatürk'ün özellikleri, sürdürülebilir liderlik özellikleri kapsamında ele alınarak kendi sözleri, eylemleri ile bu söylem ve eylemlere tanık olanların hatıralarındaki düşünceler değerlendirilmiştir. Çalışmada Atatürk’ün liderlik özellikleri sürdürülebilir lider özelliklerine göre -dürüstlük, gelecek odaklılık, ilham vericilik, yetkinlik ve özyeterlik- tartışılmıştır. Atatürk'ün sıralanan bu sürdürülebilir lider özelliklerinin tümüne sahip bir lider olduğu ve sürdürülebilir lider olarak tanımlanabileceği sonucuna ulaşılmıştır.
Evaluation of Sars-Cov-2 infection in vaccinated persons: Case of the general hospital of Douala (Cameroon)
Authors: Jean Pierre Nda-Mefo'o  , Marie Louise Njieme-Mefire  , Charles Lebon Mbele-Onana  , Elodie Ngo-Malabo  , Grace Dalle-Ngondi  , Catherine Akono-Ndi  , Bertrand Hugo Mbatchou-Ngahane  , Henry Namme-Luma  , Cécile Okalla-Ebongue
Published: September 2022

Coronavirus infection is a public health problem worldwide despite the implementation of several control measures and vaccination. The purpose of this study was to evaluate SARS-Cov-2 infection in vaccinated patients. Methods: A cross-sectional study was conducted at the Douala General Hospital from January to June 2022. Patients of both sexes, aged over 18 years, vaccinated against SARS-CoV-2 were included. Information regarding socio-demographic data, clinical manifestations, and SARS-CoV-2 vaccination was collected by individual interview. Nasopharyngeal secretions were collected by swabbing and transported to the laboratory. SARS-CoV-2 was detected using a rapid diagnostic test (antigen test) and a molecular test targeting the ORF and N genes (Daan gene® kit). Data were analyzed using StatView v5.0 and GraphPad v5.03. Results: A total of 62 patients were selected and women represented 64.5%. The mean age of the patients was 45.58 ± 13.14 with a predominance of the 40 to 50 year old age group. The patients had been vaccinated with four SARS-CoV-2 vaccines (Vaxzeria®, Jcovden-COVID-19 Vaccine Janssen®, Comirnaty Biontech-Pfizer® and Sinovac®); 50.9% of them had received the Janssen®. Viremia was higher in men aged 30 to 60 years and in those who received Janssen® vaccine. The mild form of the infection was the most common clinical presentation with 80.4% of cases. There was a delay of 3 to 5 months between vaccine administration and COVID 19 infection. Conclusion: Most of the vaccinated persons developed mild forms of COVID-19 with a mean delay of 3 to 5 months; the viremia was higher in men, in those who received the Janssen® vaccine and in those aged 30 to 60 years. Vaccination remains an effective means of preventing severe forms of SARSCoV-2 infection.
Pharmacological and toxicological effects of Nicotiana tabacum
Authors: Ali Esmail Al-Snafi
Published: September 2022

Nicotiana tabacum (Family: Solanaceae) was used traditionally for wide range of disorders, it administered externally for bites of poisonous reptiles and insects, pain, neuralgia, gout, to enhance hair growth, in the treatment of ringworm, ulcers, wounds and as respiratory stimulant. The leaves contained sesquiterpene, alkaloids, lignans, flavonoids, phenolic compounds, tannins, steroids, terpenoids, cardiac glycosides, essential oils, saponins, quinines, polypeptides, phenylpropanoids, chromanones, biphenyls and isocoumarins. The previous studied showed that Nicotiana tabacum possessed many pharmacological effects included antioxidant, antimicrobial, antiparasitic, analgesic, antidiabetic, antifertility, anti-aphthous, cytotoxic and neuropharmacological effects. The current review focused on the chemical constituents and pharmacological effects of Nicotiana tabacum.
The efficacy and safety of medicinal plants documented by clinical trials (part 1)
Authors: Ali Esmail Al-Snafi
Published: September 2022

Plants are a valuable source of a wide range of secondary metabolites, which are used as pharmaceuticals, agrochemicals, flavours, fragrances, colours, biopesticides and food additives. In the current review, PubMed, Web Science, Science Direct, Researchgate, Academia. edu and Scopus were searched to determinethe medicinal plantswhich pass the clinical trials with documented efficacy and safety.
Internal migration in India: Trends, relationship with MGNREGA and policies
Authors: Souradeep Deb
Published: September 2022

People do migrate from one place to another for various socio economic or non-economic reasons. Census 2011 found 450 million people in India are migrants, a sharp increase of 45% from the previous census. The government of India launched MGNREGA (Mahatma Gandhi National Rural Employment Guarantee Act) in 2005 to arrest out migration of unskilled landless labor force from the rural areas to urban areas by ensuring them 100 days of wage employment within their own areas. This paper actually reviews the trends and characters of internal migration in India and found that the migration is intrastate in nature and marriage is still the key reason behind it. MGNREGA couldn’t become an alternative of traditional migration from rural to urban areas in India till now. While comparing among Indian states regarding their policies towards migrants by using Interstate Migrant Policy Index (IMPEX) score of 2019, this paper found Kerala in the top of the list followed by Goa and Rajasthan.