bluuebunny/crossref_metadata_2025 huggingface dataset:
Cracking Resistance of Steam-Cured Precast Concrete Using High Alite Cement with Modified Fly Ash
Authors: Alhafez Aghiad , Miyazawa Shingo , Nito Nobukazu , Kuga Ryuichiroh , Sakai Etsuo
Published: October 2023

Cement with fly ash has rarely been used in Japan, mainly because its strength development is slower than ordinary Portland cement. In this research, the effect of the new type of fly ash (which was modified by the electrostatic belt separation method) with high alite (C3S) cement on cracking resistance of precast concrete prepared by steam curing was studied. The mechanical and shrinkage properties of the proposed fly ash concrete were compared with those of concrete made using OPC cement without fly ash. In order to study the cracking tendency of precast concrete with the proposed cement with fly ash, thermal stress analysis was conducted, taking into consideration the experimental data of concrete properties with the different concrete mix proportions. A standard precast concrete box culvert model was used in this 3D FEM analysis, and the distribution of temperature and relative humidity in the cross-section and induced restraint stress during and after steam curing were discussed. Steam-cured concrete with fly ash and high alite cement developed higher compressive strength on the first day of age than concrete with OPC. The proposed fly ash concrete developed high cracking resistance in the early days. On the other hand, the results showed that the drying shrinkage at later ages was the main cause of cracking.
The Synthesis, Crystal Structure, and Magnetic Properties of Mono-Scorpionate Eu(III) Complexes
Authors: Vostrikova Kira E. , Sukhikh Taisiya S. , Lavrov Alexander N.
Published: October 2023

Three Eu3+ complexes containing a neutral tripodal ligand possessing a predictable coordination mode have been obtained and studied. The trispyrazolylmethane complexes have an aqua ligand in the coordination sphere, forming both the mononuclear species [Eu(HCPz3)H2O(NO3)3] and the dimer [Eu(HCPz3)H2O(CF3SO3)3]2, having a Chinese lantern structure, whereas the use of the methylated tripod leads to the water-free complex, [Eu(HC(PzMe2)3)(NO3)3]. A qualitative analysis of the magnetic susceptibility of polycrystalline samples demonstrated that the magnetic properties can be described using a simple Van Vleck formula with spin–orbit coupling parameter (λ = 383 ÷ 406 cm−1) close to the values for free Eu3+ ions. The stereochemical analysis of the coordination environment of [Ln(HC(PzMe2)3)(NO3)3] has shown that these complexes can be used as diamagnetic model systems to obtain information on the crystal field effects in the paramagnetic monoradical complexes, [LnRad(NO3)3], since both types of compounds have the same type of coordination polyhedron (symmetry point group D3h) and very close Ln–donor atom distances.
A Modified Phase-Transition Model for Multi-Oscillations of Spark-Generated Bubbles
Authors: Han Rui , Chen Jiayi , Guo Taikun
Published: October 2023

The main composition within a spark-generated bubble primarily consists of vapor, accompanied by a minor presence of noncondensable gases. The phase transition exerts a substantial influence on bubble dynamics throughout various stages, a facet that has been frequently overlooked in prior research. In this study, we introduce a modified theoretical model aimed at accurately predicting the multiple oscillations of spark-generated bubbles. Leveraging the Plesset equation, which integrates second-order corrections for compressibility and non-equilibrium evaporation, we further incorporate the thermal boundary layer approximation for bubbles, as proposed by Zhong et al. We employ an adjusted phase transition duration tailored to the unique characteristics of spark-generated bubbles. Furthermore, we meticulously ascertain initial conditions through repeated gas content measurements within the bubble. Our proposed theoretical model undergoes rigorous validation through quantitative comparisons with experimental data, yielding commendable agreement in modeling the dynamic behavior of bubbles across multiple cycles. Remarkably, we uncover that the condensation rate significantly governs the behavior of spark bubbles during their initial two cycles. Finally, we investigate the dependence of spark-generated bubble dynamics on the phase transition and the presence of air. Air content exhibits a minimal impact on bubble motion prior to the initial bubble collapse, but plays a role in the bubble’s rebound thereafter.
Cellular Senescence in Cardiovascular Diseases: From Pathogenesis to Therapeutic Challenges
Authors: Li Dan , Li Yongnan , Ding Hong , Wang Yuqin , Xie Yafei , Zhang Xiaowei
Published: October 2023

Cellular senescence (CS), classically considered a stable cell cycle withdrawal, is hallmarked by a progressive decrease in cell growth, differentiation, and biological activities. Senescent cells (SNCs) display a complicated senescence-associated secretory phenotype (SASP), encompassing a variety of pro-inflammatory factors that exert influence on the biology of both the cell and surrounding tissue. Among global mortality causes, cardiovascular diseases (CVDs) stand out, significantly impacting the living quality and functional abilities of patients. Recent data suggest the accumulation of SNCs in aged or diseased cardiovascular systems, suggesting their potential role in impairing cardiovascular function. CS operates as a double-edged sword: while it can stimulate the restoration of organs under physiological conditions, it can also participate in organ and tissue dysfunction and pave the way for multiple chronic diseases under pathological states. This review explores the mechanisms that underlie CS and delves into the distinctive features that characterize SNCs. Furthermore, we describe the involvement of SNCs in the progression of CVDs. Finally, the study provides a summary of emerging interventions that either promote or suppress senescence and discusses their therapeutic potential in CVDs.
Survival Analysis of Hospital Length of Stay of COVID-19 Patients in Ilam Province, Iran: A Retrospective Cross-Sectional Study
Authors: Momeni Khalil , Raadabadi Mehdi , Sadeghifar Jamil , Rashidi Ayoub , Toulideh Zahra , Shoara Zahra , Arab-Zozani Morteza
Published: October 2023

Knowledge of the length of hospitalization of patients infected with coronavirus disease 2019 (COVID-19), its characteristics, and its related factors creates a better understanding of the impact of medical interventions and hospital capacities. Iran is one of the countries with the most deaths in the world (146,321 total deaths; 5 September 2023) and ranks first among the countries of the Middle East and the EMRO. Analysis of confirmed COVID-19 patients’ hospital length of stay in Ilam Province can be informative for decision making in other provinces of Iran. This study was conducted to analyze the survival of COVID-19 patients and the factors associated with COVID-19 deaths in the hospitals of Ilam Province. This is a retrospective cross-sectional study. Data from confirmed COVID-19 cases in Ilam Province were obtained from the SIB system in 2019. The sample size was 774 COVID-19-positive patients from Ilam Province. Measuring survival and risk probabilities in one-week intervals was performed using Cox regression. Most patients were male (55.4%) and 55.3% were over 45 years old. Of the 774 patients, 87 (11.2%) died during the study period. The mean hospital length of stay was 5.14 days. The median survival time with a 95% confidence interval was four days. The probability of survival of patients was 80%, 70%, and 38% for 10, 20, and 30 days of hospital stay, respectively. There was a significant relationship between the survival time of patients with age, history of chronic lung diseases, history of diabetes, history of heart diseases, and hospitalization in ICU (p < 0.05). The risk of dying due to COVID-19 disease was higher among men, older age groups, and patients with a history of chronic lung diseases, diabetes, and heart disease. According to the results, taking preventive measures for elderly patients and those with underlying conditions to prevent the infection of COVID-19 patients is of potential interest. Efficiency in the management of hospital beds should also be considered.
Safety of Pneumatic Dilation in Older Adults with Achalasia: An International Multicenter Cross-Sectional Study
Authors: Bar Nir , Vélez Christopher , Pasricha Trisha S. , Thurm Tamar , Ben-Ami Shor Dana , Dekel Roy , Ron Yishai , Staller Kyle , Kuo Braden
Published: October 2023

Background: Pneumatic dilation (PD) is an effective first line treatment option for many patients with achalasia. PD use may be limited in adults with achalasia who are older than 65 because of concern for adverse events (AE), and less efficacious therapies are often utilized. We explored the periprocedural safety profile of PD in older adults. Methods: An international real world cross-sectional study of patients undergoing PD between 2006–2020 in two tertiary centers. Thirty-day AEs were compared between older adults (65 and older) with achalasia and younger patients. Results: A total of 252 patients underwent 319 PDs. In 319 PDs, 18 (5.7%) complications occurred: 6 (1.9%) perforations and 12 (3.8%) emergency department referrals with benign (non-perforation) chest pain, of which 9 (2.8%) were hospitalized. No bleeding or death occurred within 30 days. Perforation rates were similar in both age groups and across achalasia subtypes. Advanced age was protective of benign chest pain complications in univariate analysis, and the limited number of AEs precluded multivariable analysis. Conclusions: The safety of PD in older adults is at least comparable to that of younger patients and should be offered as an option for definitive therapy for older patients with achalasia. Our results may affect informed consent discussions.
Characteristics Associated with Multimorbidity among Older United States Adult Opioid Users with Pain
Authors: Axon David R. , Grieser Megan
Published: October 2023

The objective of this study was to investigate the variables associated with multimorbidity status among older United States (US) adults with self-reported pain and opioid use. This study used a cross-sectional retrospective database design that included US adults aged ≥50 years with self-reported pain who used an opioid in 2019 in the Medical Expenditure Panel Survey data. Multivariable logistic regression models, weighted to produce nationally representative estimates, were used to determine variables significantly associated with multimorbidity status (≥2 versus <2 chronic conditions). Significance was determined using an a priori alpha level of 0.05. In the adjusted logistic regression analysis, those aged 50–64 (vs. ≥65 years), Hispanic (vs. non-Hispanic), employed (vs. unemployed), and who performed frequent exercise (vs. no frequent exercise) were associated with lower odds of having multimorbidity. In conclusion, these characteristics may be targets for pain management and opioid use interventions among older US adults. Further research is needed to investigate the variables associated with multimorbidity in greater detail.
Reduced-Dose Rivaroxaban Is Associated with Lower All-Cause Mortality in Older Patients with Nonvalvular Atrial Fibrillation
Authors: Chiou Wei-Ru , Su Min-I , Lee Ying-Hsiang , Lin Po-Lin , Liu Cheng-Wei
Published: October 2023

Background: Reduced-dose rivaroxaban (10 mg) was used in the J-ROCKET AF trial, demonstrating safety in the Asian population. It remains unclear whether treatment with reduced-dose versus full-dose rivaroxaban (20 mg/15 mg) is associated with all-cause mortality in older patients with nonvalvular atrial fibrillation. Proposed: To evaluate the effects of reduced-dose rivaroxaban on all-cause mortality in patients over 85. Methods: We retrospectively enrolled medical records representing the period from October 2012 to November 2016. The 2 × 2 factorial design incorporated age (≥85 vs. <85) and rivaroxaban use (reduced vs. full dose). The primary study outcomes were all-cause and cardiac-related mortality. Results: The study enrolled 2386 patients with a mean age of 76.6 ± 10.4 years; 51.8% were male. In the ≥85 group (n = 593), the reduced-dose subgroup had lower all-cause (5.3% vs. 10.6%, p = 0.02) and cardiac-related mortality (1.9% vs. 5.1%, p = 0.04), whereas the younger patients receiving reduced-dose rivaroxaban had higher all-cause mortality (3.7% vs. 1.8%, p = 0.01) but no difference in cardiac-related mortality (1.2% vs. 0.7%, p = 0.33). The rate of hospitalization for heart failure was significantly lower in the elderly group with reduced-dose rivaroxaban (7.2% vs. 15.7%, p < 0.01) but not in the younger group. After adjusting for confounders in the older group, treatment with reduced-dose rivaroxaban was associated with lower risk of all-cause mortality (adjusted HR (aHR): 0.40, 95% CI: 0.21–0.74, p < 0.01) and hospitalization for heart failure (aHR: 0.54, 95% CI: 0.29–0.99, p = 0.05). No associations were found between rivaroxaban dose and cardiac-related mortality in either group, nor between younger age and any outcome. Conclusions: Reduced-dose rivaroxaban was associated with lower risks of all-cause mortality and hospitalization for heart failure in older patients with nonvalvular atrial fibrillation. Future studies can investigate the effect of reduced-dose rivaroxaban on prognoses in elderly individuals ≥85 years in the west.
Effect of Nonsurgical Periodontal Treatment on Salivary and Plasma Superoxide Dismutase Levels of Patients Suffering from Periodontitis
Authors: Veljovic Tanja , Djuric Milanko , Mirnic Jelena , Gusic Ivana , Maletin Aleksandra , Ivic Stojan , Stojilkovic Marija , Brkic Snezana
Published: October 2023

Antioxidant capacity is frequently measured by evaluating superoxide dismutase (SOD) concentration in body fluids. The aim of this study was to compare SOD concentrations in the saliva and plasma of patients with periodontitis to those measured in a group of patients with healthy periodontium, as well as to evaluate the influence of nonsurgical periodontal therapy on salivary and plasma SOD in periodontitis patients. For this purpose, 40 systemically healthy patients aged 30–70 years who had at least 20 teeth were recruited, 20 of whom had periodontitis, and 20 served as healthy periodontitis-free controls. In all participants, periodontal status was assessed via the plaque index (PI), gingival index (GI), papilla bleeding index (PIB), probing depth (PD), and clinical attachment level (CAL), and the SOD concentration in both saliva and plasma was determined by conducting a commercial immunoenzymatic ELISA test. In periodontitis patients, periodontal indices and saliva and blood samples were taken at the beginning of the study, as well as 3 months after periodontal therapy, while in the control group, these data were gathered at the beginning of the study only. SOD values in the saliva of patients with periodontitis (0.244 U/µL) were statistically significantly higher compared with patients with healthy periodontium (0.017 U/µL). Moreover, periodontal therapy led to a statistically significant decrease in this marker in the saliva of patients with periodontitis (p = 0.023), which was comparable with that measured in the control group. On the other hand, no statistically significant differences were noted in plasma SOD values either between the two groups or at follow-up compared with baseline in the group with periodontitis. These findings suggest that the elevated salivary SOD in patients with periodontal disease may represent a mechanism of tissue protection against oxidative stress that occurs in response to periodontal disease.
Robotic First Rib Resection in Thoracic Outlet Syndrome: A Systematic Review of Current Literature
Authors: Reyes Maikerly , Alaparthi Sneha , Roedl Johannes B. , Moreta Marisa C. , Evans Nathaniel R. , Grenda Tyler , Okusanya Olugbenga T.
Published: October 2023

Thoracic outlet syndrome (TOS) involves the compression of neurovascular structures in the thoracic outlet. TOS subtypes, including neurogenic (nTOS), venous (vTOS), and arterial (aTOS) are characterized by distinct clinical presentations and diagnostic considerations. This review explores the incidence, diagnostic challenges, and management of TOS with a focus on the innovative approach of Robotic First Rib Resection (R-FRR). Traditional management of TOS includes conservative measures and surgical interventions, with various open surgical approaches carrying risks of complications. R-FRR, a minimally invasive technique, offers advantages such as improved exposure, reduced injury risk to neurovascular structures, and shorter hospital stays. A comprehensive literature review was conducted to assess the outcomes of R-FRR for TOS. Data from 12 selected studies involving 397 patients with nTOS, vTOS, and aTOS were reviewed. The results indicate that R-FRR is associated with favorable intraoperative outcomes including minimal blood loss and low conversion rates to traditional approaches. Postoperatively, patients experienced decreased pain, improved function, and low complication rates. These findings support R-FRR as a safe and effective option for medically refractory TOS.
Evaluation of Children’s Anxiety Level in Relation to a Dental Visit/Treatment and Their Parents’ Dental Fear
Authors: Jervøe-Storm Pia-Merete , Peters Lisa Patricia , Bekes Katrin , Fricke Miriam , Jepsen Søren
Published: October 2023

The patients’ fear of the dentist plays an important role in the everyday life of a dentist. The anxiety level of children in relation to dental treatment/visits and to their parents’ dental fear was evaluated in three different centers. Assessments of a modified CFSS-DS (mCFSS-DS) were performed by questionnaire with 60 children and their parents. Children’s dmft/DMFT scores, age and gender were evaluated in relation to the parents’ perception of their child’s anxiety levels. For statistical evaluation, Kruskal–Wallis and Wilcoxon tests as well as Spearman’s correlation coefficient (Spearman) were used. The significance level was set at 0.05. There were no significant differences regarding children’s mCFSS-DS between the three centers (p = 0.398, Kruskal–Wallis). The parents’ mCFSS-DS scores correlated significantly with their children’s mCFSS-DS scores (p = 0.004, Spearman). However, the mean mCFSS-DS score of the children was significantly higher than the mean score of parents’ perception of their child’s anxiety (p = 0.000, Wilcoxon). The age of the child had an influence on the mCFSS-DS score (p = 0.02, Kruskal–Wallis) but neither the children’s gender (p = 0.170, Kruskal–Wallis), nor the dmft/DMFT showed an impact (p < 0.725, Spearman). Although a positive correlation was found between the results of the children’s and parents’ questionnaire, many parents underestimated the anxiety level of their children.
Dapagliflozin Improved Cardiac Function and Structure in Diabetic Patients with Preserved Ejection Fraction: Results of a Single Centre, Observational Prospective Study
Authors: Cortés Marcelino , Lorenzo Oscar , Lumpuy-Castillo Jairo , Martínez-Albaladejo Sacramento , Taibo-Urquía Mikel , Pello Ana María , Bollas Antonio José , Orejas Miguel , Navas Miguel Ángel , Macia Ester , Martínez María Esther , Rueda Andrea , Tuñón Jose
Published: October 2023

Sodium-glucose cotransporter inhibitors (SGLT2i) have demonstrated a reduction in cardiovascular events in diabetes and heart failure (HF). The mechanisms underlying this benefit are not well known and data are contradictory. The purpose of this study is to analyse the effect of dapagliflozin on cardiac structure and function in patients with normal ejection fraction. Between October 2020 and October 2021, we consecutively included 31 diabetic patients without prior history of SGLT2i use. In all of them, dapagliflozin treatment was started. At inclusion and during six months of follow-up, different clinical, ECG, analytical, and echocardiographic (standard, 3D, and speckle tracking) variables were recorded. After a follow-up period of 6.6 months, an average reduction of 18 g (p = 0.028) in 3D-estimated left ventricle mass was observed. An increase in absolute left ventricle global longitudinal strain (LV-GLS) of 0.3 (p = 0.036) was observed, as well as an increase in isovolumetric relaxation time (IVRT) of 10.5 ms (p = 0.05). Moreover, dapagliflozin decreased the levels of plasma creatin-kinase (CK-MB) and atrial natriuretic peptide (ANP). In conclusion, our data show that the use of SGLT2i is associated with both structural (myocardial mass) and functional (IVRT, LV-GLS) cardiac improvements in a population of diabetic patients with normal ejection fraction.
Formation Transformation Method for UUV Group to Approach a Static Target
Authors: Yin Liangang , Yan Zheping , Hou Yunzhi
Published: October 2023

The unmanned underwater vehicle (UUV) group composed of UUVs carrying different kinds of detection equipment is powerful for underwater target searching and detection. In this paper, a formation transformation method, used while the mission of the UUV group transformed from searching to detecting, is proposed. Firstly, a new formation transformation strategy, in which the UUVs converged to their detection points followed by the aggregation points achieved, is proposed to improve the safety of UUVs during transformation. Following the proposed strategy, particle swarm optimization is employed to find the optimal aggregation points. Finally, possible collisions between UUVs and collisions between UUVs and targets are avoided by adding a collision avoidance algorithm based on a virtual torque field. The model prediction is used to solve the delay problem of underwater communication, and the communication results are used to correct the model prediction results. The test shows that the method is effective. The effectiveness of the proposed method is demonstrated using two simulation examples.
Host Recognition and Specific Infection of Endomelanconiopsis endophytica during Early Infection
Authors: Xie Yan , Shi Liuqing , Cheng Keke , Li Yang , Yu Shixiao
Published: October 2023

Coevolution between the pathogen and host plant drives pathogenic effector diversity. However, the molecular mechanism behind host-specific pathogenesis remains to be explored. Here, we present a 43 Mb whole-genome sequence of Endomelanconiopsis endophytica strain LS29, a host-specific pathogen of the common subtropical tree Castanopsis fissa. We described its genome annotations and identified its effector candidates. By performing temporal transcriptome sequencing of E. endophytica on C. fissa during early infection, we found that E. endophytica repressed other microbes in order to attack the tissue of the host by producing antibiotics earlier than 24 h post-inoculation (hpi). Simultaneously, a variety of effectors were secreted to recognize the host plant, but most of them showed a significantly opposing expression regulation trend after 24 hpi, indicating that 24 hpi represents a key time point between host recognition and specific infection. Furthermore, a comparison of isoenzymes showed that only a few effectors were identified as specific effectors, which were involved in hydrolyzing the compounds of the plant cell wall and releasing fatty acids during the early infection of C. fissa. Our results determined host recognition timing and identified a specific catalog of effectors, which are crucial for revealing the molecular mechanism of host-specific pathogenesis.
Assessing the Potential Risks of Digital Therapeutics (DTX): The DTX Risk Assessment Canvas
Authors: Denecke Kerstin , May Richard , Gabarron Elia , Lopez-Campos Guillermo H.
Published: October 2023

Motivation: Digital therapeutics (DTX), i.e., health interventions that are provided through digital means, are increasingly available for use; in some countries, physicians can even prescribe selected DTX following a reimbursement by health insurances. This results in an increasing need for methodologies to consider and monitor DTX’s negative consequences, their risks to patient safety, and possible adverse events. However, it is completely unknown which aspects should be subject to surveillance given the missing experiences with the tools and their negative impacts. Objective: Our aim is to develop a tool—the DTX Risk Assessment Canvas—that enables researchers, developers, and practitioners to reflect on the negative consequences of DTX in a participatory process. Method: Taking the well-established business model canvas as a starting point, we identified relevant aspects to be considered in a risk assessment of a DTX. The aspects or building blocks of the canvas were constructed in a two-way process: first, we defined the aspects relevant for discussing and reflecting on how a DTX might bring negative consequences and risks for its users by considering ISO/TS 82304-2, the scientific literature, and by reviewing existing DTX and their listed adverse effects. The resulting aspects were grouped into thematic blocks and the canvas was created. Second, six experts in health informatics and mental health provided feedback and tested the understandability of the initial canvas by individually applying it to a DTX of their choice. Based on their feedback, the canvas was modified. Results: The DTX Risk Assessment Canvas is organized into 15 thematic blocks which are in turn grouped into three thematic groups considering the DTX itself, the users of the DTX, and the effects of the DTX. For each thematic block, questions have been formulated to guide the user of the canvas in reflecting on the single aspects. Conclusions: The DTX Risk Assessment Canvas is a tool to reflect the negative consequences and risks of a DTX by discussing different thematic blocks that together constitute a comprehensive interpretation of a DTX regarding possible risks. Applied during the DTX design and development phase, it can help in implementing countermeasures for mitigation or means for their monitoring.
Commodity Prices and the US Business Cycle
Authors: van der Nest Matthew , van Vuuren Gary
Published: October 2023

This article explores the relationship between commodity price cycles and the US business cycle. Commodity price cycles are known to foster capricious macroeconomic activity, and understanding their behaviour offers valuable economic insight. The US business cycle is a key indicator of the broader economic conditions, reflecting changes in economic activity, consumer spending, and overall market conditions. By examining the dynamics and interplay between these two cycles, this study provides insights into the potential synchronisation, lag, or lead between commodity price cycles and the US business cycle. The study employs a Fourier analysis of commodity price cycles and the US business cycle. In addition, the same empirical method will be used to analyse historical rainfall patterns in the US as a means of furthering the role of historical rainfall patterns in shaping agricultural productivity and subsequent price movements. Results show dominant cycles of 14.2 years throughout the commodity price dataset, 3.8 years within the US business cycle, and 14.2 years in US historical rainfall patterns. The study also identifies several factors that influence the relationship between these two cycles, including global demand, trade policies, and financial market fluctuations.
Multimodality Cardiovascular Imaging of Cardiotoxicity Due to Cancer Therapy
Authors: Contaldi Carla , Montesarchio Vincenzo , Catapano Dario , Falco Luigi , Caputo Francesca , D’Aniello Carmine , Masarone Daniele , Pacileo Giuseppe
Published: October 2023

Cancer therapies have revolutionized patient survival rates, yet they come with the risk of cardiotoxicity, necessitating effective monitoring and management. The existing guidelines offer a limited empirical basis for practical approaches in various clinical scenarios. This article explores the intricate relationship between cancer therapy and the cardiovascular system, highlighting the role of advanced multimodality imaging in monitoring patients before, during, and after cancer treatment. This review outlines the cardiovascular effects of different cancer therapy classes, offering a comprehensive understanding of their dose- and time-dependent impacts. This paper delves into diverse imaging modalities such as echocardiography, cardiac magnetic resonance imaging, cardiac computed tomography, and nuclear imaging, detailing their strengths and limitations in various conditions due to cancer treatment, such as cardiac dysfunction, myocarditis, coronary artery disease, Takotsubo cardiomyopathy, pulmonary hypertension, arterial hypertension, valvular heart diseases, and heart failure with preserved ejection fraction. Moreover, it underscores the significance of long-term follow-up for cancer survivors and discusses future directions.
Exploring the Interplay of Muscular Endurance, Functional Balance, and Limits of Stability: A Comparative Study in Individuals with Lumbar Spondylosis Using a Computerized Stabilometric Force Platform
Authors: Alfaya Fareed F. , Reddy Ravi Shankar , Alshahrani Mastour Saeed , Gautam Ajay Prashad , Mukherjee Debjani , Al Salim Zuhair A. , Alqhtani Raee S. , Ghulam Hussain Saleh H. , Alyami Abdullah Mohammed , Al Adal Saeed , Jabour Abdullah Ali
Published: October 2023

Lumbar spondylosis, characterized by degenerative changes in the lumbar spine, often leads to pain, reduced spinal stability, and musculoskeletal dysfunction. Understanding the impact of lumbar spondylosis on musculoskeletal function, particularly lumbar extensor endurance, functional balance, and limits of stability, is crucial for improving the management and well-being of affected individuals. This study aimed to assess lumbar extensor endurance, functional balance, and limits of stability in individuals with lumbar spondylosis compared to age-matched healthy individuals and explore the correlations among these parameters within the lumbar spondylosis group. The lumbar spondylosis group consisted of 60 individuals initially screened by an orthopedician and referred to physical therapy. Age-matched healthy controls (n = 60) were recruited. Inclusion criteria encompassed adults aged 45–70 years for both groups. Lumbar extensor endurance was assessed using the Sorensen test, functional balance with the Berg Balance Scale, and limits of stability using a computerized stabilometric force platform. Lumbar extensor endurance was significantly lower in individuals with lumbar spondylosis compared to healthy controls (23.06 s vs. 52.45 s, p < 0.001). Functional balance, as assessed by the Berg Balance Scale, demonstrated a significant decrement in the lumbar spondylosis group (48.36 vs. 53.34, p < 0.001). Additionally, limits of stability variables, under both eyes-open and eyes-closed conditions, exhibited marked impairments in the lumbar spondylosis group (p < 0.001 for all variables). Within the lumbar spondylosis group, lumbar extensor endurance exhibited significant positive correlations with functional balance (0.46, p < 0.001) and negative correlations with limits of stability variables (r ranging from −0.38 to −0.49, p < 0.01 for all variables). This study underscores the significance of addressing lumbar extensor endurance, functional balance, and stability impairments in the comprehensive management of lumbar spondylosis.
Plant-Derived Natural Products and Their Biomedical Properties: Recent Advances and Future Directions
Authors: Amerikanou Charalampia , Papada Efstathia
Published: October 2023

Nature has always been a source of inspiration and innovation to humanity [...]
Influencing Factors on the Fluting in an Axial Ball Bearing at DC Bearing Currents
Authors: Safdarzadeh Omid , Capan Resat , Werner Michel , Binder Andreas , Koch Oliver
Published: October 2023

The effect of variable DC bearing current amplitude, bearing current polarity, mechanical force, rotation speed, bearing temperature, and number of the balls on the fluting in an axial ball bearing type 51208 is investigated under DC currents. The results are obtained from two different test setups with two different lubricants (mineral-oil-based grease and polyglycol oil). The speed varies between 100 rpm and 2000 rpm, the axial bearing force between 200 N and 2400 N, the DC current amplitude between 0.5 A and 20 A, the bearing temperature between 29 °C and 80 °C, the number of steel balls per bearing between 3 and 15, and the test duration between 6 h and 168 h. The results show that with a higher bearing current density and/or a higher bearing speed, a lower bearing force and/or a lower bearing temperature, a bigger number of roller elements, but also at a negative polarity of a DC electric bearing current, the occurring of fluting is more probable and occurs at an earlier stage of operation.
Role of CdTe Interface Structure on CdS/CdTe Photovoltaic Device Performance
Authors: Jayswal Niva K. , Adhikari Dipendra , Subedi Indra , Shan Ambalanath , Podraza Nikolas J.
Published: October 2023

Glancing angle deposition (GLAD) of CdTe can produce a cubic, hexagonal, or mixed phase crystal structure depending upon the oblique deposition angles (Φ) and substrate temperature. GLAD CdTe films are prepared at different Φ at room temperature (RT) and a high temperature (HT) of 250 °C and used as interlayers between the n-type hexagonal CdS window layer and the p-type cubic CdTe absorber layer to investigate the role of interfacial tailoring at the CdS/CdTe heterojunction in photovoltaic (PV) device performance. The Φ = 80° RT GLAD CdTe interlayer and CdS both have the hexagonal structure, which reduces lattice mismatch at the CdS/CdTe interface and improves electronic quality at the heterojunction for device performance optimization. The device performance of HT CdS/CdTe solar cells with Φ = 80° RT with 50 to 350 nm thick GLAD CdTe interlayers is evaluated in which a 250 nm interlayer device shows the best device performance with a 0.53 V increase in open-circuit voltage and fill-factor product and a 0.73% increase in absolute efficiency compared to the HT baseline PV device without an interlayer.
Compatibility of Sustainable Mater-Bi/poly(ε-caprolactone)/cellulose Biocomposites as a Function of Filler Modification
Authors: Hejna Aleksander , Barczewski Mateusz , Kosmela Paulina , Mysiukiewicz Olga , Piasecki Adam , Tercjak Agnieszka
Published: October 2023

Despite their popularity and multiplicity of applications, wood–polymer composites (WPCs) still have to overcome particular issues related to their processing and properties. The main aspect is the compatibility with plant-based materials which affects the overall performance of the material. It can be enhanced by strengthening the interfacial adhesion resulting from physical and/or chemical interactions between the matrix and filler, which requires introducing a compatibilizer or a proper modification of one or both phases. Herein, the impact of cellulose filler modifications with varying contents (1–10 wt%) of hexamethylene diisocyanate (HDI) on the compatibility of Mater-Bi/poly(ε-caprolactone) (PCL)-based biocomposites was evaluated. An analysis of surface wettability revealed that the filler modification reduced the hydrophilicity gap between phases, suggesting compatibility enhancement. It was later confirmed via microscopic observation (scanning electron microscopy (SEM) and atomic force microscopy (AFM)), which pointed to the finer dispersion of modified particles and enhanced quality of the interface. The rheological analysis confirmed increased system homogeneity by the reduction in complex viscosity. In contrast, thermogravimetric analysis (TGA) indicated the efficient modification of filler and the presence of the chemical interactions at the interface by the shift of thermal decomposition onset and the changes in the degradation course.
Development of a 6-DOF Parallel Robot for Potential Single-Incision Laparoscopic Surgery Application
Authors: Pisla Doina , Hajjar Nadim Al , Gherman Bogdan , Radu Corina , Antal Tiberiu , Tucan Paul , Literat Ruxanda , Vaida Calin
Published: October 2023

This paper presents the development of a 6-DOF (Degrees of Freedom) parallel robot for single-incision laparoscopic surgery (SILS). The concept of the robotic system is developed with respect to a medical protocol designed by the medical experts in the team targeting a SILS procedure in urology. The kinematic model of the robotic system was defined to determine the singularities that may occur during functioning. FEM analyses were performed to determine the components of the robotic structure that may compromise the rigidity of the robotic system, and these components were redesigned and integrated into the final design of the robot. To verify the kinematic model a series of numerical and graphical simulations were performed, while to test the functionality of the robotic system, a low-cost experimental model was developed. The accuracy of the experimental model was measured using an optical motion tracking system.
Decomposition Is All You Need: Single-Objective to Multi-Objective Optimization towards Artificial General Intelligence
Authors: Xu Wendi , Wang Xianpeng , Guo Qingxin , Song Xiangman , Zhao Ren , Zhao Guodong , He Dakuo , Xu Te , Zhang Ming , Yang Yang
Published: October 2023

As a new abstract computational model in evolutionary transfer optimization (ETO), single-objective to multi-objective optimization (SMO) is conducted at the macroscopic level rather than the intermediate level for specific algorithms or the microscopic level for specific operators; this method aims to develop systems with a profound grasp of evolutionary dynamic and learning mechanism similar to human intelligence via a “decomposition” style (in the abstract of the well-known “Transformer” article “Attention is All You Need”, they use “attention” instead). To the best of our knowledge, it is the first work of SMO for discrete cases because we extend our conference paper and inherit its originality status. In this paper, by implementing the abstract SMO in specialized memetic algorithms, key knowledge from single-objective problems/tasks to the multi-objective core problem/task can be transferred or “gathered” for permutation flow shop scheduling problems, which will reduce the notorious complexity in combinatorial spaces for multi-objective settings in a straight method; this is because single-objective tasks are easier to complete than their multi-objective versions. Extensive experimental studies and theoretical results on benchmarks (1) emphasize our decomposition root in mathematical programming, such as Lagrangian relaxation and column generation; (2) provide two “where to go” strategies for both SMO and ETO; and (3) contribute to the mission of building safe and beneficial artificial general intelligence for manufacturing via evolutionary computation.
On Consistency of the Nearest Neighbor Estimator of the Density Function for m-AANA Samples
Authors: Liu Xin , Wu Yi , Wang Wei , Zhu Yong
Published: October 2023

In this paper, by establishing a Bernstein inequality for m-asymptotically almost negatively associated random variables, some results on consistency for the nearest neighbor estimator of the density function are further established. The results generalize some existing ones in the literature. Some numerical simulations are also provided to support the results.
Enhancing Autonomous Guided Vehicles with Red-Black TOR Iterative Method
Authors: Dahalan A’Qilah Ahmad , Saudi Azali , Sulaiman Jumat
Published: October 2023

To address an autonomous guided vehicle problem, this article presents extended variants of the established block over-relaxation method known as the Block Modified Two-Parameter Over-relaxation (B-MTOR) method. The main challenge in handling autonomous-driven vehicles is to offer an efficient and reliable path-planning algorithm equipped with collision-free feature. This work intends to solve the path navigation with obstacle avoidance problem explicitly by using a numerical approach, where the mobile robot must project a route to outperform the efficiency of its travel from any initial position to the target location in the designated area. The solution builds on the potential field technique that uses Laplace’s equation to restrict the formation of potential functions across operating mobile robot regions. The existing block over-relaxation method and its variants evaluate the computation by obtaining four Laplacian potentials per computation in groups. These groups can also be viewed as groups of two points and single points if they’re close to the boundary. The proposed B-MTOR technique employs red-black ordering with four different weighted parameters. By carefully choosing the optimal parameter values, the suggested B-MTOR improved the computational execution of the algorithm. In red-black ordering, the computational molecules of red and black nodes are symmetrical. When the computation of red nodes is performed, the updated values of their four neighbouring black nodes are applied, and conversely. The performance of the newly proposed B-MTOR method is compared against the existing methods in terms of computational complexity and execution time. The simulation findings reveal that the red-black variants are superior to their corresponding regular variants, with the B-MTOR approach giving the best performance. The experiment also shows that, by applying a finite difference method, the mobile robot is capable of producing a collision-free path from any start to a given target point. In addition, the findings also verified that numerical techniques could provide an accelerated solution and have generated a smoother path than earlier work on the same issue.
Risk Premium of Bitcoin and Ethereum during the COVID-19 and Non-COVID-19 Periods: A High-Frequency Approach
Authors: Núñez-Mora José Antonio , Contreras-Valdez Mario Iván , Santillán-Salgado Roberto Joaquín
Published: October 2023

This paper reports our findings on the return dynamics of Bitcoin and Ethereum using high-frequency data (minute-by-minute observations) from 2015 to 2022 for Bitcoin and from 2016 to 2022 for Ethereum. The main objective of modeling these two series was to obtain a dynamic estimation of risk premium with the intention of characterizing its behavior. To this end, we estimated the Generalized Autoregressive Conditional Heteroskedasticity in Mean with Normal-Inverse Gaussian distribution (GARCH-M-NIG) model for the residuals. We also estimated the other parameters of the model and discussed their evolution over time, including the skewness and kurtosis of the Normal-Inverse Gaussian distribution. Similarly, we determined the parameters that define the evolution of the estimated variance, i.e., the parameters related to the fitted past variance, square error and long-term average value. We found that, despite the market uncertainty during the COVID-19 emergency period (2020 and 2021), the selected cryptocurrencies’ return volatility and kurtosis were even greater for several other subperiods within our sample’s time frame. Our model represents an analytical tool that estimates the risk premium that should be delivered by Bitcoin and Ethereum and is therefore of interest to risk managers, traders and investors.
General Fractional Noether Theorem and Non-Holonomic Action Principle
Authors: Tarasov Vasily E.
Published: October 2023

Using general fractional calculus (GFC) of the Luchko form and non-holonomic variational equations of Sedov type, generalizations of the standard action principle and first Noether theorem are proposed and proved for non-local (general fractional) non-Lagrangian field theory. The use of the GFC allows us to take into account a wide class of nonlocalities in space and time compared to the usual fractional calculus. The use of non-holonomic variation equations allows us to consider field equations and equations of motion for a wide class of irreversible processes, dissipative and open systems, non-Lagrangian and non-Hamiltonian field theories and systems. In addition, the proposed GF action principle and the GF Noether theorem are generalized to equations containing general fractional integrals (GFI) in addition to general fractional derivatives (GFD). Examples of field equations with GFDs and GFIs are suggested. The energy–momentum tensor, orbital angular-momentum tensor and spin angular-momentum tensor are given for general fractional non-Lagrangian field theories. Examples of application of generalized first Noether’s theorem are suggested for scalar end vector fields of non-Lagrangian field theory.
BaMSGAN: Self-Attention Generative Adversarial Network with Blur and Memory for Anime Face Generation
Authors: Li Xu , Li Bowei , Fang Minghao , Huang Rui , Huang Xiaoran
Published: October 2023

In this paper, we propose a novel network, self-attention generative adversarial network with blur and memory (BaMSGAN), for generating anime faces with improved clarity and faster convergence while retaining the capacity for continuous learning. Traditional self-attention generative adversarial networks (SAGANs) produce anime faces of higher quality compared to deep convolutional generative adversarial networks (DCGANs); however, some edges remain blurry and distorted, and the generation speed is sluggish. Additionally, common issues hinder the model’s ability to learn continuously. To address these challenges, we introduce a blurring preprocessing step on a portion of the training dataset, which is then fed to the discriminator as fake data to encourage the model to avoid blurry edges. Furthermore, we incorporate regulation into the optimizer to mitigate mode collapse. Additionally, memory data stored in the memory repository is presented to the model every epoch to alleviate catastrophic forgetting, thereby enhancing performance throughout the training process. Experimental results demonstrate that BaMSGAN outperforms prior work in anime face generation, significantly reducing distortion rates and accelerating shape convergence.