bluuebunny/crossref_metadata_2025 huggingface dataset:
Synergistic Treatment Approach for Pulmonary Fibrosis: Prednisone and Cyclophosphamide Regulation of Circular RNA MORF4L1 and MicroRNA-29a-3p Targeting BRD4
Authors: Wang Dan , Zhao Hao , Li Ben , Quan Feng
Published: August 2024

This study aimed to explore the effect of prednisone (PDN) combined with cyclophosphamide (CTX) on bleomycin-induced pulmonary fibrosis (PF) in rats via circular RNA mortality factor 4 like 1 (MORF4L1)/microRNA (miR)-29a-3p/Bromodomain protein 4 (BRD4) axis.
A rat model of PF was induced by bleomycin and treated with PDN combined with CTX, and the lentiviral vectors that interfered with MORF4L1, miR-29a-3p, or BRD4 expression were injected into the tail vein at the same time. The mRNA expressions of MORF4L1, miR-29a-3p, BRD4, and fibrosis-associated proteins including fibronectin, connective tissue growth factor, and collagen I were detected by real-time quantitative polymerase chain reaction. The expression level of BRD4 protein in rat lungs was detected by Western blot analysis. Lung pathology of rats was observed by hematoxylin and eosin and Masson’s trichrome staining. Apoptosis was observed by terminal deoxynucleotidyl transferase dUTP nick end labeling staining. The targeting relationship between miR-29a-3p and MORF4L1 or BRD4 was verified by the bioinformatics website and dual luciferase reporter experiment.
Bleomycin-induced PF enhanced MORF4L1 and BRD4 expression, inhibited miR-29a-3p expression, injured lung tissue, increased mRNA expression of fibrosis-related markers, and induced apoptosis in the lung tissue of rats. PDN combined with CTX had a therapeutic effect on PF in rats, which was further promoted by down-regulating MORF4L1 or up-regulating miR-29a-3p. After down-regulating miR-29a-3p or up-regulating BRD4, the effect of down-regulating MORF4L1 was reversed. MORF4L1 could bind to miR-29a-3p to target BRD4.
In short, PDN combined with CTX can effectively improve PF through downregulating MORF4L1 to enhance miR-29a-3p-targeted regulation of BRD4.
Single Mutation different Clinical Findings: IGLL1 Defect
Authors: Naiboğlu Sezin , Gezdirici Alper , Ulaş Selami , Turan Işılay , Çeliksoy Mehmet Halil , Aydoğmuş Çiğdem
Published: August 2024

Agammaglobulinemia is a rare inherited immunodeficiency disorder characterized by low or absent B cells with absent immunoglobulins. While X-linked agammaglobulinemia (XLA) is the most common type other genetic forms of agammaglobulinemia have been identified. During early childhood, passively transferred maternal Immunoglobulin G protects against various infections. The depletion of these antibodies begins between 6 and 12 months of age, resulting in recurrent sinusitis, bronchitis, and pneumonia in children with X-linked agammaglobulinemia. However, less common autosomal recessive forms of agammaglobulinemia present with more severe clinical features, leading to earlier diagnosis. Herein we present the case of a two-month-old male with IGLL1 gene defect and different clinical findings of family members with the same mutation.
Impact of Yoga beyond Physical Training on the Cardiovascular System: An Updated Review
Authors: Verma Samman , Hatwal Juniali , Batta Akash
Published: August 2024

Cardiovascular disease (CVD) poses a significant health challenge in both developing and developed nations, with unparalleled morbidity, mortality, and economic tolls. Primary prevention of CVD through lifestyle modifications has been emphasized to address this issue. Yoga, an ancient practice dating back thousands of years with roots in the Harappan and Mohenjo-Daro civilizations, offers a potential solution. Hatha yoga, which includes physical movements and breathing techniques, is the most commonly practiced form today. The health benefits of yoga have recently gained attention and are being researched globally. Yoga is beneficial in both primary and secondary prevention of diseases, particularly CVD and its risk factors.
This review aims to explore the physiology of yoga, recent studies on its effect on the prevention and control of CVD, and the clinical implications of these findings.
The Impact of Mean Arterial Pressure during Cardiopulmonary Bypass on Postoperative Outcomes in Coronary Artery Bypass Graft Surgery
Authors: Shamsi Afzal , Alaroofa Senan Salim , Firoozabadi Mehdi Dehghani , Alkazzaz Dena A. , Nooralishahi Behrang , Mehrabanian Mohammadjavad
Published: August 2024

Background: Maintaining an optimal mean arterial pressure (MAP) is vital for cerebral blood flow and the overall health of patients undergoing coronary artery bypass graft (CABG) surgery. This study investigated the impact of low MAP on cerebral blood flow and in-hospital clinical outcomes in CABG candidates at our hospital.
Methods: We compared a convenience sample of 55 patients with a low MAP (55 mmHg) and 54 patients with a high MAP (75 mmHg) who underwent CABG at Tehran Heart Center in 2023. We recorded the patients' demographic and clinical characteristics by measuring cerebral oximeter readings and lactate levels pre- and post-operation. We then compared the baseline and postoperative characteristics between the 2 groups and determined the impact of MAP on their postoperative changes.
Results: The groups were statistically similar at baseline, except for a lower pH in the low MAP group (55 mmHg) (P=0.016). The preoperative and postoperative measurements (including lactate levels and cerebral oximeter readings) did not differ between the groups. However, heart rate was significantly higher in the high MAP group (75 mmHg) (P=0.034). The adjusted effect of baseline MAP on selected postoperative characteristics showed that it could significantly but inversely influence heart rate (β coefficient=-5.952; P=0.017) and had a borderline effect on troponin (β coefficient=1.734; P=0.051) and HCO3 (β coefficient=0.785; P=0.062).
Conclusion: MAP did not significantly influence clinical outcomes in our study. Nonetheless, maintaining an optimal MAP is essential for preventing cerebral injury and ensuring adequate cerebral oxygenation in CABG patients.
Dairy Product Consumption among Adults and Determining the Population-Attributable Risk of Common Non-Communicable Diseases: A Population-Based Cross-Sectional Study
Authors: Doosti-Irani Amin , Cheraghi Parvin , Shirmohammadi Nasrin , Khdemi-Monfared Bahraeh , Cheraghi Zahra
Published: August 2024

Background: Over the past decade, Iranian households have experienced a decline in dairy product consumption. This study aimed to evaluate the population-attributable risk of prevalent non-communicable diseases related to dairy product consumption.
Methods: This cross-sectional analytical study involved 628 adults over 18 years old in Hamadan City in 2021. Clusters were selected based on comprehensive urban health centers. The standardized Iranian version of the food frequency questionnaire was used. Participants were categorized into 3 levels of dairy product consumption: >1 serving per day, 1–2 servings per day, and ≥3 servings per day.
Results: The mean age of the 628 participants was 38.05 (SD: 12.5), with 42.36% being male. Cheese (54.5%), yogurt (39.7%), and milk (30.4%) were consumed most frequently. The prevalence of insufficient dairy product consumption was 48.6%, higher than that reported in previous studies. Insufficient dairy product consumption was associated with hypertension (9.3%), cardiovascular disease (5.6%), and osteoporosis (5.1%).
Conclusion: Individuals with lower education levels, female gender, lowest quartile of socioeconomic status, and those diagnosed with cardiovascular disease were more likely to have insufficient dairy product consumption. Insufficient dairy product consumption was associated with hypertension, cardiovascular disease, and osteoporosis.
COVID-19 and Acute Myocardial Infarction: Exploring Clinical Factors and Treatment Expenditures
Authors: Rajaie Soheila , Rezapour Aziz , Tajdini Masih , Salehbeygi Shahrzad , Azari Samad
Published: August 2024

Background: The concurrence of acute myocardial infarction (AMI) with COVID-19 can complicate the clinical conditions of patients and affect the patterns of hospital resource utilization. This study aimed to investigate and analyze the direct treatment costs of AMI patients with concurrent COVID-19.
Methods: This cross-sectional study collected and analyzed clinical data, including symptoms, readmission, and interventions, and treatment cost data for all patients at Tehran Heart Center using SPSS26 software. The mean medical costs of patients from January through May 2022 were also calculated.
Results: The COVID-19 group was composed of 72.9% male and 27.1% female patients, whereas the non-COVID-19 group consisted of 67.3% male and 32.7% female patients. Most of the patients in the COVID-19 group (60%) were in the elderly age group (>65 y). The length of stay was 8.70±5.84 days for the COVID-19 group and 6.31±4.42 days for the non-COVID-19 group. The mortality rate in the COVID-19 group was 24%, higher than the 5% rate in the other group. Additionally, the average total treatment costs were $6384.54±$6760.13 in the COVID-19 group and $6362.49±$4343.07 in the non-COVID-19 group (P>0.78 and P>0.050).
Conclusion: The study found that the COVID-19 group had a significantly higher in-hospital mortality rate than the non-COVID-19 group. During the follow-up period, the incidence of complications (chest pain and heart failure) was higher in the non-COVID-19 group. It also showed that longer hospital stays resulted in higher treatment costs.
Heart Stiffening in Pediatric Dilated Cardiomyopathy: Causes of Severity
Authors: Noori Noor Mohammad , Teimouri Alireza
Published: August 2024

Background: Cardiomyopathy, characterized by heart stiffness, can lead to heart failure. This study aimed to investigate aortic stiffness in children with dilated cardiomyopathy (DCM) to better understand its contribution to disease severity.
Methods: This case-control study compared 48 children with DCM with 96 healthy children over a 10-year period starting in 2011. Aortic strain, aortic stiffness index, aortic distensibility, and pressure strain elastic modulus were measured. These parameters, along with several echocardiographic measures, were compared between the DCM and control groups. Statistical analyses were performed using SPSS 18, with a significance threshold set at a P value below 0.05.
Results: The participants included 57.6% boys, with 58.3% in the DCM group and 57.35% in the control group (χ2=0.014, P=0.905). The age range was 2 to 18 years, with mean ages of 11.08±4.63 years for the DCM group and 10.77±2.82 years for the control group (P=0.691). Significant differences between groups were observed in aortic distensibility (P=0.004), aortic stiffness β index (P=0.001), and pressure strain elastic modulus (P=0.004). Post-treatment analyses based on ejection fraction and fractional shortening cutoffs indicated no changes in elasticity parameters except for the aortic stiffness β index, which varied according to the Ross classification.
Conclusion: Children with DCM exhibited reduced aortic strain and aortic distensibility, as well as elevated aortic stiffness β index and pressure strain elastic modulus
Pediatric Cardiac Surgery Complications and the Risk Factors: A Single-Center Study
Authors: Mirzaaghayan Mohammadreza , Vahdati Zahra , Nematian Hossein , Memarian Sara , Heidari Morteza , Askari Mohammad Hossein , Gharib Behdad
Published: August 2024

Background: This study aimed to determine postoperative cardiac and noncardiac complications and their association with the use of cardiopulmonary bypass (CPB), surgical outcomes (length of hospital and ICU stays), dependence on mechanical ventilation, and mortality.
Methods: This retrospective cross-sectional study was conducted on pediatric patients aged 0 to 18 who underwent open or closed cardiac surgery over a 1-year period. The use of CPB support, CPB duration, cardiac surgery complexity according to the risk-adjusted classification for congenital heart surgery (RACHS-1), and demographics were examined as potential risk factors associated with an increased number of postoperative complications. The study was performed at the Children’s Medical Center, a teaching hospital affiliated with Tehran University of Medical Sciences in Iran.
Results: A total of 283 surgeries were included in our study. Seventy-six (26.9%) of the study population experienced at least 1 complication. Our analysis revealed that increased CPB durations were associated with higher odds of cardiac complications, with an odds ratio of 1.02 (P=0.002). Moreover, higher RACHS-1 levels were significantly associated with greater numbers of cardiac and noncardiac complications. Additionally, prolonged mechanical ventilation and open-heart surgery intensive care unit (OH-ICU) stays were significantly associated with cardiac and noncardiac complications. Our logistic regression analysis found no association between demographic and clinical risk factors, the number of complications, and mortality.
Conclusion: Postoperative complications occurred in 27% of pediatric heart surgeries. Prolonged mechanical ventilation and OH-ICU stays were significantly associated with cardiac and noncardiac complications. However, no significant association was found between postoperative complications and mortality.
Coarctation Balloon Angioplasty in a Rare Case with Congenitally Corrected Transposition of the Great Arteries and Ebstein’s Anomaly
Authors: Alipour Afrouz , Alizadehm Behzad , Zargaran Bita
Published: August 2024

The coexistence of aortic coarctation, Ebstein’s anomaly, and transposition of the great arteries is an extremely rare occurrence. In this case report, we present a unique instance of complex congenital heart disease in a neonate who exhibited respiratory distress and cyanosis at birth. Echocardiography revealed several significant findings: congenitally corrected transposition of the great arteries, Ebstein’s tricuspid anomaly, moderate-to-severe tricuspid regurgitation, a small muscular ventricular septal defect, and an abnormal left arch with severe coarctation of the aorta. Due to the patient’s unstable hemodynamic status, balloon angioplasty was performed. Subsequent long-term clinical follow-up confirmed the efficacy of this intervention.
Atypical de Winter ECG: What is the Culprit?
Authors: Rachmi Dita Aulia , Mulia Eka Prasetya Budi , Fagi Rosi Amrilla
Published: August 2024

Various ECG patterns can help determine the location of the occluded coronary artery and the extent of threatened myocardium. The reported positive predictive value for de Winter ECG in predicting acute left anterior descending artery occlusion is inconsistent. Additionally, the morphology of ST depression and other ECG findings may have varying degrees of severity and prognostic significance. This case demonstrates the importance of integrating multiple ECG findings, such as ST elevation, Q waves, and the R/S ratio, with the location of the de Winter pattern on various ECG leads to accurately predict the culprit artery and assess the anatomical extent of myocardial ischemia.
Aortic Valve-in-Valve in a Patient with Infective Endocarditis after COVID-19 Infection: A Case Report
Authors: Alizadeasl Azin , Abdi Seifollah , Firouzi Ata , Pouraliakbar Hamidreza , Sadeghipour Parham , Azarfarin Rasoul , Parsa Niloufar Akbari
Published: August 2024

Few cases of transcatheter aortic valve implantation (TAVI) following infective endocarditis (IE) have been reported. In this presentation, we discuss the feasibility of TAVI in a degenerated bioprosthetic valve affected by IE.
We examine a rare case involving an elderly man with a degenerated bioprosthetic aortic valve complicated by IE 6 months after a COVID-19 infection. The patient was successfully treated with valve-in-valve intervention following antibiotic therapy for the acute phase of the infection. This resulted in excellent outcomes with no complications in the early postprocedural period and during follow-up visits.
For patients with a destructed bioprosthetic aortic valve due to IE and residual dysfunction after healing, valve-in-valve intervention can be a safe and effective treatment option, particularly for those at high risk for surgery.
Modeling Consumer Overall Acceptance for Traditional Spice-Based Ready-to-Drink Using Artificial Neural Network and Kansei Engineering
Authors: Alfiani Ririn Nur , Ushada Mirwan , Ainuri Makhmudun , Falah Mohammad Affan Fajar
Published: August 2024

Measuring consumer acceptance of food products is challenging, primarily because the process is susceptible to bias. Several studies have reported that this challenge can be addressed through Kansei engineering through verbal and nonverbal response measurements. Therefore, this study aimed to predict consumer overall acceptance using artificial neural networks (ANN) and Kansei engineering. A total of 30 respondents participated in this study to test nine different samples of traditional spice-based ready-to-drink (RTD). The overall acceptance score and Kansei responses, including verbal and nonverbal, were then measured. Each sample was served cold in a 60-mL cup labeled with a three-digit random code, and the panelists were successfully presented with the nine drinks. All participants were asked to rank each Kansei word scale based on the intensity of their feelings during the assessment. The heart rate (HR) and skin temperature (ST) were also measured as nonverbal responses in real time. The results showed that Kansei's responses and respondent background best predicted overall acceptance. The optimal model architecture had ten input neurons, two hidden neurons, and one output neuron (10-2-1). The training, validation, and testing data showed that the performance of ANN was satisfactory, with a low error rate (RMSE) and a high coefficient of correlation value (R2). Based on the findings, the developed model could inspire and motivate further studies and development in industries to develop appropriate products for potential consumers, thereby revolutionizing the food industry.
Strategy to Optimize Quality Culture to Increase Lecturer's Commitment to Implementing Three Pillars in Higher Education
Authors: Sihotang Hotmaulina , Murniarti Erni
Published: August 2024

Quality lecturers have a very strategic role in determining the quality of higher education (HE). Lecturers have the duties and responsibilities of carrying out three pillars in HE, namely education, research and service and community service in accordance with the demands of lecturer workload and developing a culture of quality. This research uses a quantitative approach with a survey method. The research was conducted at the Indonesian Christian University. The population was all lecturers and a sample of 104 people using sampling techniques. Data collection techniques using questionnaires using the Likert model and two expert opinions. Data analysis used descriptive and inferential with useed of SPSS 26 and SITOREM (Scientific Identification Theory to Conduct Operation Research in Education Management). The research results findings: (a) lecturers' perceptions of lecturers' commitment to implementing good three pillars of HE; (b) lecturers' perceptions of quality culture are very good, (c) the relationship between lecturers' commitment to quality culture is moderate but positive and significant; (d) strategies to improve the culture of quality in HE include leaders becoming role models, lecturers adhering to their main duties and responsibilities, lecturers having a growth mindset and being agile in changing, lecturers being active in activities outside campus such as taking part in conferences, being resource persons.
Psychological Characteristics of Internet Addiction in Students in Problem Life Situations (COVID, War)
Authors: Chuyko Halyna , Chaplak Yan , Koltunovych Tetiana
Published: August 2024

The relevance of this research lies in the fact that the number of Internet addicts in the world is constantly growing (the premise of which we consider the possibilities of Internet content that open up to a person in the virtual space), and the situation can turn into a public health problem. The purpose of the article is to carry out a theoretical analysis of the phenomenon of Internet addiction and, based on it, conduct an empirical study of Internet addiction of students, its connection with their personal traits and their satisfaction with life in difficult life situations: during the COVID-19 pandemic (n=88) and war (n=87). The research used the following methods: Internet Addiction Test (K. Young), CIAS, Chen-Internet-Addiction-Scale (S.-H. Cnen), Techniques for diagnosing predisposition to 13 types of addictions (G.V. Lozova), Test T. Leary, Questionnaire “Life Satisfaction Index” (B. Neugarten, R. Havighurst, Sh. Tobin), Oxford Happiness Inventory, OHI. Mathematical processing of research results was carried out using statistical package SPSS 17.0. The analysis of approaches to the understanding of Internet addiction by scientists leads to the conclusion that it is a behavioral deviation that manifests itself in a person’s excessive spending of time in the Internet space due to reluctance to return to real life; this is exactly information addiction. The main symptoms of Internet addiction: the tendency of an individual to choose being on the Internet before any other types of his activity; a change in his/her state of consciousness, a gradual increase in the time spent on the Internet, the lack of an objective assessment of the negative consequences of Internet addiction. As a result of the study, it was found that: Internet addiction can be combined with other types of addiction, Internet addicts are characterized by certain types of attitude towards others and a lack of feeling of satisfaction with life; Respondents who are less dependent on the Internet tend to positively evaluate themselves, be consistent in achieving their goals, fall into other addictions less often, and activate situationally necessary types of attitude towards others.
Evolution of the Verb State Category in Germanic Languages: A Neuroscientific Perspective
Authors: Shapochkina Olga , Kovalenko Valentyna , Gaidash Anna , Zaichenko Olena , Poroshyna Valentyna , Sazhko Lilia
Published: August 2024

Relevance of research. The article examines the process of verb formation in Germanic languages, as well as the peculiarities of the grammatical semantics of verbs at different historical stages of the development of Germanic languages. Using the comparative-historical method, the functioning of verbs in texts of Germanic languages ​​was investigated as an aspect of neurolinguistic science. Research results. The article proves that most modal verbs of Germanic languages ​​have undergone significant semantic transformations. The study of texts of different historical stages of language development shows that verbs evolved through semantic transformation. Time frames of the formation of secondary semantics were revealed. The theoretical and practical significance lies in the fact that this resarch allows a detailed study of the features of the emergence of the primary, as well as the secondary, subjective semantics of verbs in Germanic languages ​​from a neuroscientific point of view. It should be noted that the list of subjective values ​​still raises many questions and discussions. The German language has an extremely clear system of means of expressing modal values. The scientific novelty of the article lies in the neurolinguistic approach to the study of the evolution of Germanic verbs. The article aims to study the evolution of verbs in the German language in the context of neurolinguistics. To achieve the goal, the method of comparative analysis was used. This made it possible to consider the evolution of the verb through a comparative study of texts at the main stages of speech development. To solve these problems, texts reflecting the state of the language at each historical stage were studied.
Sports Games in the Context of Developing Children’s Coordination Ability as a Component of Physical Development
Authors: Ruban Asya , Radovenchyk Anastasiia , Semal Natalia , Bilohur Vlada , Chkhailo Mykola , Dzhym Viktor
Published: August 2024

The article explores how sports games and physical exercises influence the development of children’s coordination an essential aspect of their physical development. Its relevance is underscored by the current critical state of children’s health and the rising number of children with special needs. Today’s youth must become healthy individuals, integrating intellectual, moral, vocational and physical education. The article aims to define such concepts as “ability”, “coordination” and “coordination ability”, analyze existing literature on how physical exercises affect children’s coordination and examine the role of kinesiological exercises in enhancing children’s motor skills. Research methods include theoretical and systematic analysis of relevant scientific literature. As is known, physical activity plays a crucial role in the effective development of children’s coordination ability. This article analyzes those studies that underscore the significance of engaging in activities such as basketball, volleyball, rowing and choreography to improve it. It also examines the advantages of kinesiological exercises. A key insight of this research is that high coordination levels not only foster physical development but also enhance social and cognitive growth, thereby boosting children’s learning capabilities and their interactions with peers. Thus, it is vital to incorporate physical exercises into children’s routines, considering their age and individual needs.
Classifying Rural Parks: A Case Study in Iowa
Authors: Klein-Hewett Hans
Published: August 2024

Many park professionals use classification systems to simplify complex park spaces into efficient and manageable descriptions. In the United States, the most common classification systems use park size and service area as determinants of a park’s class. While those variables are important in urban spaces, they often fail to capture the unique realities of rural parks. This can lead to misunderstandings, as rural parks are frequently evaluated, programmed, and planned using urbanor-mative assumptions. To address that gap, this paper proposes a new Iowa Rural Park Classification System (IRPCS) that focuses on park function, a crucial de-terminant of rural park use due to the distances between rural destinations. The development of the IRPCS involved collecting data from 749 recreation spaces across an eight-county study area in central Iowa. This data was then analyzed us-ing iterative decision trees to identify, test, and refine the variables that differenti-ate each park class. While ultimately abandoned due to limitations in flexibility, these decision trees played a valuable role in shaping the final park classes.The IRPCS differentiates rural parks from their urban counterparts by highlight-ing the unique variables and characteristics that make them essential utilities. This focus will spark further research and discussions dedicated to rural parks. Additionally, the IRPCS establishes a rural-specific park lexicon, enabling park managers and planners to discuss and analyze rural parks with greater precision.
Why Is It So Hard to Talk About Same-Sex Experience? A Case Study of Veiled Silence in a Research Relationship through Reflexive and Autoethnographic Lens
Authors: Gammon Thi
Published: August 2024

Research into intimate details of human life can be challenging for the parties involved. This article is a case study of a research situation in which I, as an interviewer, failed to elicit information from a male Vietnamese interviewee who evaded discussing specific details of his romantic life. I argue that this situation—the man’s avoidance of sharing details of his feelings toward people of the same sex and my discomfort in facing his avoidance—reveals a culture of silence regarding same-sex experiences in Vietnam. The study utilizes autoethnographic anecdotes of my experience of growing up in such a culture and observing similar evasive attitudes. It also adopts a reflexive approach that delves into segments of my second research encounter with the interviewee as well as my internal struggles, including feelings of anxiety and guilt about probing into an informant’s romantic life. It seeks to enrich Lisa A. Mazzei’s concept of “veiled silence,” which describes the deliberate non-engagement with taboo topics by linking it with the idea of a “culture of silence,” or a disempowering social environment, and discussing these concepts in the context of Vietnam. It also contributes to the literature on LGBTQ+ matters in Vietnam and qualitative research methods by recommending greater attention to silence in research encounters, which can offer unexpected insights for studies into sensitive issues.
Optimization of NPS Fertilizer Rate and Row Spacing for Growth and Yield of Fenugreek (Trigonella foenum-graecum L.) at Wolaita Sodo, Southern Ethiopia
Authors: Beze Kindu , Shumbulo Abrham
Published: August 2024

Background: Fenugreek (Trigonella foenum greecum L.) is an important self-pollinated seed spice crop belonging to family Fabaceae. Fenugreek production and productivity in the study area is very low as compared to its potential yield mainly due to inappropriate application of fertilizer rates and plant spacing. Hence, field experiment was conducted in 2022 at Wolaita Sodo, Ethiopia. The objective of study was to investigate and determine optimum inter row spacing and NPS fertilizer for growth and yield of fenugreek. Methods: Treatments consisted of four NPS fertilizer rates (0, 50, 100 and 150 kg ha-1) and four inter-row spacing (10, 20, 30 and 40 cm) that gave a total of 16 treatments laid out in randomized complete block design (RCBD) with three replications. Result: The ANOVA result indicated that the main effects of fertilizer rates, inter-row spacing and their interactions significantly (p less than 0.05) affected most traits investigated. Accordingly, the highest number of pod (17.10) and seed yield per plant (13.70 g) were recorded by application of 150 kg ha-1 NPS with 40 cm inter row spacing. The maximum total above ground biomass (3.46 t ha-1) and seed yield (1.60 t ha-1 ) were obtained by application of 150 kg ha-1 NPS with 10 and 20 cm inter row spacing, respectively. Moreover, the economic analysis revealed that the highest net benefit (279,130 ETB ha-1 ) with marginal rate of return of 2,976% was obtained by 150 kg NPS ha-1 with 20 cm inter row spacing. Hence, 150 kg ha-1 NPS with 20 cm inter row spacing could be recommended for production and productivity of fenugreek in Wolaita area.
Groupwork with disadvantaged communities in North West, Lokaleng village in South Africa- social responsibility
Authors: Smit Elizabeth
Published: August 2024

North West University has in its many community engagement endeavours and projects developed a “We deliver” project to give back to the community as part of its social responsibility initiative.
The department of social work used this platform to advance self-help, education, mutual aid, social relief and general development within the community. Generalist approach of Kirst-Ashman, (2002) was particularly used which incorporated multiple levels of intervention. Attempts at improving the life of the disadvantaged involves imparting of knowledge about the manifestation of social problems like poverty, unemployment and self-defeating behaviours like teenage pregnancy, teenage alcohol abuse and drug misuse.  Social group work as one of the primary methods was used to reach the community through learners focusing on empowerment and skilling.  The latter was provided by the relevant stakeholder Department of Social Development (DSD).  The target group which served as a link to the community was high school learners in Lokaleng Village near Mafikeng, North West Province.  The results were shared with the leaders of the community who served as gatekeepers and who will ensure sustainability.
 
Keywords:  group work, community, disadvantaged, social responsibility, sustainability
O etno, o folk e o popular: trajetórias conceituais na etnomusicologia brasileira
Authors: Fonseca Edilberto
Published: August 2024

Este artigo tem por objetivo debater, por meio de referências bibliográficas e documentais, de que maneira conceitos e categorias como etno, folk e popular foram historicamente utilizados e ressignificados em pesquisas etnográficas sobre música e cultura nos ambientes acadêmicos e não acadêmicos do país. O objetivo foi trazer novos elementos sobre a constituição da etnomusicologia brasileira desde os primeiros registros fonográficos realizados no país até o início da década de 1970, revelando tendências, influências e também o modo como se deu a difusão do termo dentro e fora do universo acadêmico. Surgida no meio acadêmico europeu e estadunidense, a etnomusicologia começa a se instituir no Brasil no início do século passado por meio da atuação de musicólogos, folcloristas e acadêmicos do nascente campo das ciências sociais e humanas. Procurou-se observar especialmente o papel ativo e decisivo exercido por agentes, entidades e instituições nacionais e internacionais nessa trajetória.
Construction of a novel tetraphenylethylene-based supramolecular dimer for improving the generation of reactive oxygen species and photocatalytic performance
Authors: Jiang Man , Li Xin-Long , Han Ning , Yao Xian-Ya , Wang Fa-Dong , Niu Kai-Kai , Liu Hui , Yu Shengsheng , Xing Ling-Bao
Published: August 2024

Using supramolecular strategies to improve the generation of reactive oxygen species is a practical and environmentally friendly method, but it is also a difficult undertaking. In this study, we created and produced a vinylpyridine-modified tetraphenylethylene derivative TPE-Py-I, which has excellent solubility in water and has the ability to construct supramolecular dimers (2TPE-Py-I@CB[8]) in an aqueous solution through host-guest interaction with cucurbit[8]uril (CB[8]). The supramolecular dimer demonstrated a remarkable aggregation-induced emission response, with the fluorescence progressively intensifying upon the introduction of CB[8]. Meanwhile, the formation of supramolecular dimer also greatly improved the intersystem crossing effect of the molecular assembly system, so that the generation ability of reactive oxygen species including singlet oxygen (1O2) and superoxide anion radical (O2•-) were enhanced, which provided a basis for its application as an excellent supramolecular photosensitizer in photocatalytic organic reactions. To our delight, 2TPE-Py-I@CB[8] exhibits excellent photocatalytic properties, making it suitable for both phosphine photooxidation and cross-dehydrogenative coupling reactions. This work provides a non-covalent strategy for the development of supramolecular dimer photosensitizers and broadens its application in the field of photocatalytic organic conversion.
Silver Nanoparticle Biosynthesis using Distimake vitifolius Extract for Enhancement of Antibacterial and Antioxidant Activity
Authors: Tahya Candra Yulius , Karnelasatri Karnelasatri , Irawati Wahyu , Munthe Sri Wahyu Ningsih
Published: August 2024

ABSTRACT. The biological method for silver nanoparticle synthesis emphasizes green synthesis, which is faster, environmentally safer, facile, energy-efficient, and cost-effective. It provides good alternatives to physical and chemical methods. In this research, we have synthesized silver nanoparticles using D. vitifolius ethanolic extract. The 38 natural compounds of flavonoid, phenolic or polyphenol compositions have been determined by LC-MS/MS-QTOF which is carried out using UNIFI software equipped with a mass spectrum library of active substances from natural ingredients from the Waters database. Silver nanoparticle (Dv-AgNP) was characterized by using TEM and SEM where the average diameter of nanoparticle was seen <100 nm and confirmed by PSA analysis that the Z-average is 62.73 ± 0.71 nm. EDS spectrum confirmed the silver element as a major element of the particles. PI value of Dv-AgNP is 0.557, while the zeta potential is -17.37 ± 1.53 mV. Dv-AgNP can inhibit the growth of P. aeruginosa (amoxicillin resistant) with an inhibition zone of 15.83 ± 2.36 mm, and K. pneumoniae with an inhibition zone is 10.03 ± 0.55 mm. These are moderate inhibitory activities. The antioxidant result of the Dv-AgNP suspension solution shows that the IC50 is 0.58 mM. The IC50 of the crude extract is 752 ppm and is categorized as very weak antioxidant activity.
 
Keywords: Antibacterial; D. vitifolius; silver nanoparticle.
Synthesis and Characterization of A Fascinating Coordination Polymer Metal-Organic Framework Featuring Cobalt (II) and 4,4'-Bipyridine
Authors: Kurniawan Cepi
Published: August 2024

ABSTRACT. This investigation delineates the fabrication, comprehensive characterization, and electrochemical evaluation of a one-dimensional Cobalt-based Metal-Organic Framework (Co-MOFs), constructed from 4,4’-Bipyridine ligands and Cobalt (II) ions. The study aimed to perfect the synthesis protocol, elucidate the structural and compositional attributes of the resultant MOF, and probe its electrochemical performance. Utilizing the reflux method, renowned for its efficacy and eco-compatibility, we synthesized the MOF and affirmed its formation through a suite of analytical techniques, including Infrared (IR) spectroscopy, Ultraviolet-Visible (UV-Vis) spectroscopy, Atomic Absorption Spectroscopy (AAS), and electrical conductivity measurements. The synthesized Co-MOFs, chemically notated as [Co2(4,4'-bpy)2(SO4)(H2O)2]SO4·H2O, manifested as a one-dimensional coordination polymer. X-ray Diffraction (XRD) analysis unveiled its monoclinic crystallinity within the C2 space group. Electrochemical characterization uncovered a reversible redox system, evidenced by a robust peak current ratio (IPa/IPc = 7.5), indicative of efficient electron transfer processes. Furthermore, the Co-MOFs significantly augmented the kinetics of the oxygen evolution reaction (OER) in an alkaline aqueous solution, highlighting its potential as a superior catalyst in energy-related electrochemical applications. This work not only contributes to the field of MOF synthesis but also sets the stage for future explorations into their practical applications in sustainable energy systems.
 
Keywords: Electrochemical properties, metal-organic framework, oxigen evolution reaction catalyst, 4,4’-bipyridine.
Assessing the synergistic effects of inorganic, organic, and biofertilizers on rhizosphere properties and yield of maize
Authors: Susilowati Lolita Endang , Sukartono Sukartono , Akbar Muhammad Firman , Kusumo Bambang Hari , Suriadi Ahmad , Leksono Amin Setyo , Fahrudin Fahrudin
Published: August 2024

A single and long-term use of inorganic fertilizers harms soil quality. Therefore, it is highly recommended that inorganic fertilizers be combined with other fertilizers. This study explores the synergistic effect of inorganic, organic, and biofertilizers on maize rhizosphere properties and production. Biochar (BC) and compost (OF) were applied as organic sources, a consortium of phosphate solubilizing bacteria (PSB) was applied as phosphate biofertilizers, while urea and NPK-PONSKA fertilizers (IF) were used as inorganic fertilizers. A greenhouse experiment was designed as a completely randomized arrangement involving six treatments in triplicate, namely control (only IF), a combination of IF+BC, IF+PSB, IF+BC+PSB, IF+PSB+OF, and IF+BC+OF+PSB. The best changes in soil microbial and chemical properties, maize root dry weight, and production were observed in the IF+BC+OF+PSB combination, followed by IF+OF+PSB, IF+BC+PSB and (IF+BC; IF+PSB) and control treatment, respectively. A fertilizer combination involving the addition of BC (IF+BC, IF+BC+PSB, IF+BC+OF +PSB) significantly increased soil organic C content and soil pH compared to without biochar (IF+PSB and IF+OF+PSB). A higher root dry weight also results in higher maize production. Maize production Increased in the 4, 3, and 2 combinations compared to production in the control by 43.11%, 31.32-36.55%, and 18.57%-21.34%, respectively. In conclusion, the synergy of biochar, compost, and PSB, when integrated with fertilizer, can improve soil quality and the sustainability of maize production. This study will be useful in developing sustainable nutrient management programs to increase crop productivity with high efficiency in using inorganic fertilizers.
Critical Discourse Analysis: Advice via Instagram Social Media Regional Heads in The Use of Technology in Public Education
Authors: Setiawan Budhi , Saddhono Kundharu , Rohmadi Muhammad , Wardana Muhammad Aditya Wisnu
Published: August 2024

The prevention of the Covid-19 pandemic which took place in early 2020 – 2022 made regional leaders disseminate information about preventing Covid-19 through their respective social media by relying on access to information technology and social media owned by regional leaders. This research aims to analyze critical discourse based on Teun van Dijk's method which is divided into microstructure, superstructure and microstructure aspects. The method used in this research is a qualitative descriptive method with the type of research in the form of library research or library research which focuses on documentary analysis which refers to on the Instagram posts of regional heads Wahidin Halim (Governor of Banten Province) @wh_wahidinhalim, Anies Baswedan (Governor of DKI Jakarta) @aniesbaswedan, Ridwan Kamil (Governor of West Java) @ridwankamil, Ganjar Pranowo (Governor of Central Java) @ganjar_pranowo, and Khofifah Indar Parawansa ( Governor of East Java) @khofifah.ip. The results of research in critical discourse analysis according to Teun A. Van Djik's model are divided into three aspects, namely macro structure, superstructure and micro structure. This aspect can be found in social media posts with the same pattern, so it can be concluded that the aspect of critical discourse analysis in Instagram posts during the Covid-19 pandemic was that regional heads (governors) gave recommendations and appeals to the public to comply with health protocols and reduce activities outside the home.
Cerita Ratu Tribhuwana Wijayatunggadewi Sebagai Sumber Ide Perancangan Motif Batik Majapahit
Authors: Rismawati Aristya Rizky Rismawati , Indarti Indarti
Published: August 2024

Ratu Tribhuwana Wijayatunggadewi adalah salah satu penguasa wanita terkemukadan memainkan peran yang signifikan dalam mengatur dan memperluas wilayahkekuasaan Majapahit. Penelitian ini bertujuan untuk mengetahui 1) prosesperancangan motif batik Majapahit dengan sumber ide cerita Ratu TribhuwanaWijayatunggadewi, 2) hasil jadi motif batik Majapahit dengan sumber ide RatuTribhuwana Wijayatunggadewi. Metode yang digunakan adalah Double DiamondModel yang terdiri dari 4 tahap yaitu discover, define, develop, dan deliver. Padatahap awal merangkum sumber ide untuk membuat moodboard dengan tema yangsudah ditentukan yang mengarah desain motif batik. Tahap kedua yaitumengembangkan moodboard yang telah dibuat menjadi beberapa stilasi. Tahapketiga yaitu menyusun stilasi menjadi 6 pengembangan motif batik. Tahap keempatyaitu proses produksi prototipe salah satu desain batik Majapahit dengan sumberide ratu Tribhuwana Wijayatunggadewi. Penelitian ini menghasilkan 6 desain motifbatik cerita ratu Tribhuwana Wijayatunggadewi, dan dari 6 desain tersebut terpilih1 desain yang diwujudkan dalam bentuk kain batik motif cerita ratu TribhuwanaWijayatunggadewi dengan ukuran kain 200 x 115 cm.
Penerapan Teknik Rajut Crochet Granny Square Pada Longtorso
Authors: Adinda Kurnia Putri  , Ruhidawati Cucu
Published: August 2024

Rajut crochet merupakan produk kerajinan tangan yang menggunakan benang sebagai bahan utama. Produk yang dapat dibuat sangat beraneka ragam, salah satunya adalah busana longtorso. Tujuan dari penelitian ini adalah (1) Menciptakan busana longtorso yang dapat digunakan sebagai busana luar, (2) menciptakan busana longtorso yang dapat digunakan sebagai busana pesta, (3) menarik minat anak muda agar tertarik dengan produk rajut crochet. Metodologi penelitian yang digunakan dalam penelitian ini adalah metodologi tiga tahap penciptaan seni kriya yang meliputi; (1) tahap eksplorasi yang meliputi pencarian sumber ide, konsep, dan landasan penciptaan, (2) tahap perancangan desain karya, (3) tahap perwujudan karya. Setelah melalui berbagai proses tersebut dihasilkan sebuah produk longtorso yang dapat digunakan pada kesempatan pesta.
Studi Visual Escapism Pada Mahasiswa Sebagai Inspirasi Perancangan Artwear
Authors: Napitupulu Marisi , Soemardi Ardita Ayulestari , Shinta Fairus
Published: August 2024

Escapism merupakan kecenderungan untuk mencari pengalih perhatian atau kebebasan dari kenyataan yang tidak menyenangkan melalui hiburan atau fantasi lainnya. Banyak orang mengalami Escapism, termasuk mahasiswa juga melakukan kegiatan escapism ketika merasa jenuh / bosan. Berkaitan dengan hal tersebut, diperlukan adanya rancangan fashion sebagai bentuk visual mengenai escapism pada kalangan mahasiswa. Tujuan dari rancangan busana ini adalah mendeskripsikan visual Escapism mahasiswa ke arah positif melalui rancangan fashion dan menghasilkan rancangan fashion berupa artwear sebagai upaya untuk mengarahkan Escapism mahasiswa ke arah yang positif. Metode yang digunakan yaitu metode kualitatif berupa studi literatur, wawancara, dan kuesioner. Metode perancangan yang digunakan dalam penelitian ini adalah sebagai berikut: (1) riset escapism sebagai bahan penelitian; (2) riset visual berupa artwear; (3) Moodboard dan Colour Scheme; (4) Sketsa Motif yang melambangkan escapism bagi mahasiswa; (5) eksplorasi, teknik laser cut, layering, heating dan foil painting; (6) tahap produksi; dan (7) hasil akhir perancangan berupa pakaian artwear yang melambangkan visual art escapism bagi mahasiswa. Berdasarkan hal tersebut, didapatkan hasil perancangan berupa post production yang menghasilkan 2 (dua) rancangan artwear dengan menggunakan material pvc, foil, crinoline, tulle, spandex dan menggunakan teknik heating, foil painting dan layering yang menghasilkan 2 (dua) rancangan artwear berupa creative video dan catalogue melalui sosial media.
Pengaplikasan Kain Lurik Dengan Corak Kinanthi Pada Dress Ready to Wear “Kinanthi Asih”
Authors: Puspita Sari Wulan , Kamila Nisrina Juhaida , Naraya Raissa
Published: August 2024

Menurut Kamus Besar Bahasa Indonesia (1990), lurik adalah kain tenun yang memiliki corak jalur-jalur. Dalam Kamus Lengkap Bahasa Jawa (Mangunsuwito: 2002) pengertian lurik adalah corak lirik-lirik atau lorek-lorek, yang berarti garis-garis dalam bahasa Indonesia. Pada penelitian kali ini, kami mencoba mengaplikasikan kain lurik corak kinanthi dengan sumber ide dari lapis Surabaya pada dress ready to wear, khususnya dengan warna coklat kuning. Objek yang diteliti adalahkoleksi busana “Kinanthi Asih: koleksi dress ready to wear lurik kinanthi”. Pendekatan penelitian yang digunakan adalah survei kualitatif dengan menggunakan kuesioner online sebagai alat pengumpulan data. Responden yang terlibat adalah wanita dewasa muda berusia 18 hingga 25 tahun. Hasil penelitian menunjukkan bahwa desain busana dengan motif lurik corak kinanthi mendapat respon positif yang tinggi dari responden, dengan ketiga desain yang dievaluasi masuk dalam kategori yang memenuhi harapan responden. Artinya, desain-desain tersebut berhasil menggambarkan harmoni antara tradisi dan kekinian dalam industri fashion Indonesia.