bluuebunny/crossref_metadata_2025 huggingface dataset:
Malignant Mucosal Melanoma of the Eustachian Tube With Extension Into the Ipsilateral External Ear Canal: A Case Report and Review of the Literature
Authors: Li Lifeng , London Nyall R. , Chen Xiaohong
Published: February 2020

Mucosal melanoma arising in the middle ear or eustachian tube is uncommon. We present a patient with hearing loss and otalgia found to have mucosal melanoma which occurred in the eustachian tube with extension into the middle ear cavity and external ear canal. Otologic clinics was consulted and biopsy of the mass located at the external canal was performed to ascertain the pathological diagnosis. The patient refused immunotherapy and surgery instead of undergoing radiotherapy and died from hepatic metastasis 8 months later. The mucosal melanoma originated from the eustachian tube with extension into the external ear canal is exceedingly rare, and the differential diagnosis should be considered for tumors in external ear canal.
Comparison of 2 Different Intratympanic Methylprednisolone Injection Schedules in Combination With Intravenous Dexamethasone for Unilateral Sudden Sensorineural Hearing Loss
Authors: Lyu Yanlu , Zeng Fanqian , Yan Min , Zhou Zhou , Zhang Wei , Liu Ming , Ke Chaoyang
Published: February 2020

Sudden sensorineural hearing loss is a common otologic disease in clinic. Systemic and intratympanic steroid treatment have been proved to be effective, but the regimens vary from center to center. The purpose of the study is to analyze the effects of the combined application of intravenous dexamethasone and intratympanic methylprednisolone injection in different time strategies for the treatment of unilateral sudden sensorineural hearing loss. A retrospective chart review was performed for the period from March 2016 to June 2018 at our Department of Otorhinolaryngology—Head and Neck Surgery. A total number of 61 patients who met the academy criteria for unilateral sudden hearing loss were included and grouped based on the time to introduce intratympanic methylprednisolone. All the patients received intravenous dexamethasone 10 mg once daily for 5 days, followed 5 mg once daily for the next 7 days. Intratympanic methylprednisolone (40 mg) was injected every other day 4 times into all patients. This regimen was commenced on day 1 in group 1 and on day 6 in group 2. The pre and posttreatment pure-tone audiograms were analyzed. Sixty-one patients met our inclusion criteria. No significant differences were observed between patients’ demographics or pretreatment hearing thresholds. In the 3 months posttreatment pure-tone audiogram assessment, the mean hearing threshold improvement were similar between groups with no frequency specificity. The curative rate in both groups were similar and satisfying. Two patients with diabetes mellitus had persistent small perforations. Some patients had other transient discomfort that disappeared before discharge. The different timing of initiation of intratympanic methylprednisolone injection does not significantly affect the outcome of the treatment for sudden sensorineural hearing loss. Thus, we suggest that intratympanic steroid injection should not be applied as a first-line method except for patients who do not respond early to systemic steroid therapy.
Institutions, contexts, and ethnic violence in comparative perspective
Authors: Lee Feng-yu , Lin Tse-min
Published: February 2020

Which combinations of government structures and electoral systems create better frameworks for addressing ethnic violence? Is there any one-size-fits-all institutional solution to violent ethnic conflict? Why or why not? These questions are of substantial importance to scholars and policymakers alike, but the extant literature does not provide a systematic and thorough exploration. In this article, we argue that the effects of political institutions on ethnic violence are moderated by parameters of ethnic configurations. Through a large comparative study, we find that institutions are relevant when ethnic groups are not geographically dispersed, and whether ethnic minorities face a majority group also matters. For concentrated minorities facing a majority, semi-presidential-proportional and presidential-proportional systems are more effective in reducing violence. In cases involving concentrated minorities facing no majority, parliamentary-non-proportional systems are associated with the most intense violence. We conclude that states seeking to alleviate ethnic violence by institutional engineering must take contexts seriously.
Methylprednisolone may be associated with improved lung compliance in acute respiratory distress syndrome patients on veno-venous extracorporeal membrane oxygenation
Authors: Tabatabai Ali , Menaker Jay , Stene Edward , Kufera Joseph A , Rabinowitz Ronald P , Kon Zachary , Herr Daniel L , Scalea Thomas M
Published: February 2020

Introduction:

Methylprednisolone has been used for acute respiratory distress syndrome with variable results. Veno-venous extracorporeal membrane oxygenation use in acute respiratory distress syndrome has increased. Occasionally, both are used. We hypothesized that methylprednisolone could improve lung compliance and ease weaning from extracorporeal membrane oxygenation in acute respiratory distress syndrome patients.

Methods:

We retrospectively reviewed all patients in our veno-venous extracorporeal membrane oxygenation unit treated with methylprednisolone over a 20 month period. Methylprednisolone was initiated for inability to wean off veno-venous extracorporeal membrane oxygenation. Dynamic compliance (Cdyn) was calculated at cannulation, methylprednisolone initiation, and decannulation. Demographics, extracorporeal membrane oxygenation–specific data, and ventilator data were collected. Wilcoxon rank-sum test was used to test for differences in dynamic compliance.

Results:

A total of 12 veno-venous extracorporeal membrane oxygenation patients received methylprednisolone. Mean age was 50 (±15) years. Seven had influenza. Methylprednisolone was started on median Day 16 (interquartile range: 11-22) of veno-venous extracorporeal membrane oxygenation. In total, 10 patients had veno-venous extracorporeal membrane oxygenation decannulation on median Day 12 (7-22) after methylprednisolone initiation. Two patients died before decannulation. The 10 decannulated patients had initial median dynamic compliance (mL × cm H2O−1) of 12 (7-23), then 16 (10-24) at methylprednisolone initiation, and then 44 (34-60) at decannulation. Dynamic compliance was higher at decannulation than methylprednisolone initiation (p = 0.002), and unchanged from cannulation to methylprednisolone initiation for all patients (p = 0.97). A total of 10 patients had significant infections. None had significant gastrointestinal bleed or wound healing issues.

Conclusion:

Methylprednisolone may be associated with improved compliance in acute respiratory distress syndrome allowing for decannulation from veno-venous extracorporeal membrane oxygenation. High rates of infection are associated with methylprednisolone use in veno-venous extracorporeal membrane oxygenation. Further studies are required to identify appropriate patient selection for methylprednisolone use in patients on veno-venous extracorporeal membrane oxygenation.
Factors influencing self-care in outpatients with external fixation in China
Authors: Xing Jun , Sun Ning , Li Laiyou , Lv Dongmei , Geng Shuling , Li Yuqian
Published: February 2020

Objective

This study was performed to investigate factors influencing self-care agency in outpatients with external fixation support.

Methods

Using a cross-sectional study approach, 110 outpatients with external fixation from a single Chinese hospital were evaluated from May 2018 to October 2018. Consecutive sampling was performed, and variables included demographic data, health knowledge regarding external fixation, and self-care skills. Open and closed survey questions were used.

Results

The mean self-care agency score was 101.70 ± 20.14, with 36 (35.3%) outpatients scoring high. Demographic variables did not significantly influence the self-care level. However, health knowledge was significantly correlated with self-care skills, indicating that knowledgeable outpatients were more likely to be better at self-care.

Conclusions

Outpatients with external fixation support need higher levels of health knowledge. The level of self-care agency in the present study was in the moderate range. Outpatients with external fixation support with higher health knowledge are more likely to have higher self-care skills.
Improvement in liver stiffness measurement for diagnosis of liver fibrosis in patients with concurrent chronic hepatitis B and nonalcoholic fatty liver disease
Authors: Xu Nan , Xie Qinxiu , Li Jiang , Gao Yufeng , Li Xu
Published: February 2020

Objective

This study was performed to clarify the influence of nonalcoholic fatty liver disease (NAFLD) on liver stiffness measurement (LSM) and establish a new diagnostic model.

Methods

A retrospective cohort of 601 patients with chronic hepatitis B (CHB) was enrolled as the derivation group, and a prospective cohort of 30 patients with concurrent CHB and NAFLD was enrolled as the validation group.

Results

The area under the receiver operating characteristic curve of LSM in patients with CHB without NAFLD (0.792) was higher than that in patients with concurrent CHB and NAFLD (0.720) in diagnosing significant liver fibrosis. Patients with concurrent CHB and NAFLD had significantly higher LSM values than those without NAFLD among the overall F0-F1 patients (6.88 vs. 5.80). The LSM value in the higher controlled attenuation parameter (CAP) quartile was significantly higher than that in the normal CAP quartile among F0-F1 patients (6.80 vs. 5.74). The efficacy of our new diagnostic model for liver fibrosis (Fibro-NAFLD) was higher than that of LSM in both study groups.

Conclusion

NAFLD with a high CAP value increases the risk of false-positive diagnosis of significant fibrosis. The Fibro-NAFLD model improves the diagnostic efficacy of LSM in patients with concurrent CHB and NAFLD.
Coexistent pulmonary cryptococcal infection and pulmonary sarcoidosis: a case report and literature review
Authors: Zhou Bo , She Jianqing , Yang Lan , Zhu Bo
Published: February 2020

Cryptococcus is an encapsulated, yeast-like fungus commonly responsible for infections in individuals with impaired T cell-mediated immune responses, including those with acquired immune deficiency syndrome or taking immunosuppressive agents such as steroids or cyclosporine. However, pulmonary fungal infection is rare in patients with untreated sarcoidosis. We report a case of coexistent pulmonary cryptococcal infection in a 43-year-old man with pulmonary sarcoidosis in North-western China. The patient was diagnosed with sarcoidosis via right anterior mediastinal lymph node biopsy and lung biopsy by bronchoscopy. He was treated with oral prednisone 25 mg/day and achieved complete remission of all symptoms. However, repeat chest computed tomography examination revealed enlarged nodules in the left lower lobe, but decreased bilateral diffuse small nodules in the lungs. Computed tomography-guided percutaneous lung puncture biopsy revealed cryptococcal infection. This case highlights the need to consider fungal infection in patients with sarcoidosis at initial presentation, irrespective of their use of immunosuppressive medication.
Evaluation of Medication Administration Timing—Are We Meeting Our Goals?
Authors: Furnish Craig , Wagner Samantha , Dangler Angela , Schwarz Kerry , Trujillo Toby , Stolpman Nancy , May Sondra
Published: February 2020

Background:

Per the Centers for Medicare and Medicaid Services (CMS) Code of Federal Regulations (CFR) 482.23(c) regarding medication administration, hospital policies and procedures must identify time-critical scheduled medications which must be administered within 30 minutes either before or after the scheduled dosing time, for a total administration window of 1 hour.

Objective:

The general objective of this analysis was to determine whether there was a difference in meeting medication administration goals when comparing time-critical to non-time-critical scheduled medication administration in both intensive care units (ICUs) and general medical floors at a large, academic medical center.

Methods:

Data were collected in 6 inpatient nursing units (3 general medical units and 3 ICUs) during the month of June 2017. Electronic medical record charge data for medications were used to evaluate timeliness of medication administration.

Results:

In total, 69,794 medication administrations were evaluated. Of 389 administrations of time-critical scheduled medications, 268 (69%) were administered on time. Of 69,405 administrations of non-time-critical scheduled medications, 58,099 (84%) were administered on time ( P < 0.001). ICUs had a higher percentage of on-time administrations than general medical units (89% vs 77%, P < 0.001), and nurses had a higher percentage of on-time administrations than respiratory therapists (84% vs 63%, P < 0.001).

Conclusions:

Non-time-critical scheduled medications were more commonly administered on time compared with time-critical scheduled medications. Staff education and optimizations to the electronic health record (EHR) are interventions that may improve administration of time-critical scheduled medications.
Keeping mum: The mediation of military conflict in the everyday mothering of middle-class Israeli Palestinian and Jewish women
Authors: Golden Deborah , Erdreich Lauren
Published: February 2020

The article examines how Israeli Palestinian and Jewish middle-class mothers mediate military conflict to young children, through silence and talk. This mediation is underpinned by dissonance between the mandate to protect children from the adult world and to ready them for it, and between the idea of children as individuals and conflict as collective engagement. The article explores the discourses and practices used for managing this twofold dissonance, including differences in the privilege of silence for Palestinian and Jewish mothers.
Investigations on the tribological behavior of functionally gradient iron-based brake pad material
Authors: Govindaraju M , Megalingam A , Murugasan Jayaprakash , Vignesh R Vaira , Kota Pavan Kalyan , Ram A Sumanth , Lakshana P , Kumar V Naveen
Published: February 2020

In this study, a functionally gradient iron-based brake pad material was developed and the tribological behavior was studied. The functionally gradient specimen had more copper near the base plate and more abrasives towards the top, which provides excellent joint strength and serves the purpose of braking, respectively. The layers had a hybrid composition of metallic materials (Fe, Cu), and abrasives (silicon carbide and aluminum oxide) to improve the strength, wear resistance, and toughness. Graphite was added to stabilize the specimen's thermal and friction characteristics at high temperature. The microstructure, wear rate, and friction coefficient of the functionally gradient specimen and the conventionally sintered specimen were evaluated. The results indicate that the wear resistance of the functionally gradient specimen is higher than the wear resistance of conventional specimen.
Reconstruction and analysis of the aberrant lncRNA–miRNA–mRNA network in systemic lupus erythematosus
Authors: Xu H , Chen W , Zheng F , Tang D , Liu D , Wang G , Xu Y , Yin L , Zhang X , Dai Y
Published: February 2020

Objective

A new perspective of determining the pathophysiology of systemic lupus erythematosus (SLE) development is required. The current study explores the aberrant expression of long non-coding RNAs (lncRNA), microRNA (miRNA) and mRNA. The study further constructs and analyses the lncRNA–miRNA–mRNA network to elucidate their gene regulation roles in SLE.

Method

We extracted mRNA, lncRNA and miRNA from the whole venous blood of 20 SLE patients and 20 normal control (NC) healthy individuals. A lncRNA–mRNA–miRNA network in SLE was constructed using a bioinformatics approach. Subsequently, Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses were performed using the Cytoscape plug-in BinGo, the DAVID database and Cytoscape software to explore the function of mRNAs in this network.

Result

A total of 855 mRNA, 7311 lncRNA and 134 miRNA with differentially expressed profiles were identified. Meanwhile, we established a competing endogenous RNA (ceRNA) subnetwork composed of 52 differentially expressed lncRNAs (DElncRNAs), seven differentially expressed miRNAs and 10 differentially expressed mRNAs. We extracted the subnetwork from the ceRNA network and found that three novel miRNAs were key: hsa-miR-145, hsa-miR-17 and hsa-miR-143. We also deduced that the DElncRNAs MIAT and NEAT1 might play crucial roles in the pathogenesis of SLE. The results were verified by bioinformatics analysis.

Conclusion

Our results provide a novel perspective for studying lncRNA-related and miRNA-related ceRNA networks in SLE.
How Does Education Hone Reasoning Ability?
Authors: Bunge Silvia A. , Leib Elena R.
Published: February 2020

A belief about education that dates back several millennia is that in addition to imparting specific facts, it hones general cognitive abilities that can be leveraged for future learning. However, this idea has been a source of heated debate over the past century. Here, we focus on the question of whether and when schooling hones reasoning skills. We point to research demonstrating cognitive benefits of both broad and specific educational experiences. We then highlight studies that have begun to elucidate underlying mechanisms of learning. Given our society’s substantial investment in education, it behooves us to understand how best to prepare individuals to participate in the modern workforce and tackle the challenges of daily living.
Alimentary necrobacillosis in alpacas
Authors: Carvallo Francisco R. , Uzal Francisco A. , Flores Carlos , Diab Santiago S. , Giannitti Federico , Crossley Beate , Wünschmann Arno
Published: February 2020

Ulcers of the oral cavity, esophagus, and gastric compartments of South American camelids are uncommon. Multifocal-to-coalescing ulcers were identified in the oral cavity, esophagus, and/or gastric compartments of 5 alpacas submitted for postmortem examination. Fusobacterium necrophorum was isolated from the lesions in all alpacas, in combination with other aerobic and anaerobic bacteria. In 4 of these cases, F. necrophorum–associated lesions were considered secondary to neoplasia or other chronic debilitating conditions; in 1 case, the alimentary ulcers were considered the most significant autopsy finding. It is not known if this agent acted as a primary or opportunistic agent in mucosal membranes previously damaged by a traumatic event, chemical insult, immunodeficiency, or any other debilitating condition of the host.
PedestriANS: a bipedal robot with adaptive morphology
Authors: Ahmad Huthaifa , Nakata Yoshihiro , Nakamura Yutaka , Ishiguro Hiroshi
Published: February 2020

In diverse situations, humans produce natural and adaptable bipedal locomotion by cooperatively manipulating the interactions among the different parts of their bodies and the environment. Therefore, to realize a robot with adaptable behavior, it should be enabled to adjust its morphology accordingly in response to environmental changes. From this perspective, this study introduces the development of a bipedal robot with adaptive morphology. By implementing an actuator network system (ANS), the robot is able to manipulate the physical characteristics of its legs and the way they interact with each other. Two experiments have been conducted: main and supplementary experiments. The main experiment examined how effective is adjusting the robot’s morphology on changing the robot’s behavior. The experiment was conducted on different ground materials and under different connection patterns between the robot’s legs. During the experiment, the robot’s behavior was evaluated in reference to four aspects: walking style, stability, speed, and moving direction. The supplementary experiment took the results of the main experiment and used it to improve the robot’s behavior during locomotion. The robot was enabled to automatically switch between the different connection patterns of the ANS, which in turn changed the interaction between the robot’s legs and generated a more suitable dynamics for the surrounding environment.
Effectiveness of a pharmaceutical instruction video for adherence to dermatopathy treatment in patients with cancer receiving the anti-epidermal growth factor receptor antibody
Authors: Sato Junya , Ishikawa Hiroshi , Yasuda Yoko , Tanaka Rei , Kiyohara Yoshio , Yamawaki Yuki , Endo Megumi , Shino Michihiro
Published: February 2020

Background

Dermatopathy develops as a side effect in patients receiving anti-epidermal growth factor receptor antibody treatment. Topical moisturizers are used for the prevention and treatment of this dermatopathy. Active participation of patients in their own treatment is important for the appropriate application of topical preparations. We prepared a pharmaceutical instructional video for adhering to the topical application protocol. In this study, we investigated the effectiveness of this pharmaceutical instructional video on treatment adherence.

Methods

Study participants were patients with cancer receiving the anti-epidermal growth factor receptor antibody for the first time. A pharmacist instructed the patients on how to use the pharmaceutical instruction video. Daily topical preparation use following the video demonstration was assessed. The effectiveness of the pharmaceutical instruction video was evaluated by assessing the adherence of patients who did not use the pharmaceutical instruction video for the past 2 periods (26 months; controls 1 and 2). The incidence of side effects was compared between the two control groups and the group of patients who received the pharmaceutical instruction video.

Results

The amount of topical preparation consumed (median, g/day) by patients who received patient compliance instructions using the pharmaceutical instruction video was 9.8 g/day, as compared with control group 1 (4.5 g/day) and control group 2 (5.5 g/day) ( p <  0.001). There was no difference in the incidence of side effects during the three periods.

Conclusion

The use of visual instructional media for patient compliance by pharmacists may be effective in maintaining and improving treatment adherence.
Advantages of everolimus therapeutic drug monitoring in oncology when drug–drug interaction is suspected: A case report
Authors: Strobbe Geoffrey , Pannier Diane , Sakji Ilyes , Villain Alexandre , Feutry Frédéric , Marliot Guillaume
Published: February 2020

Introduction

Drug interactions involving everolimus are fairly well known because of its common use, primarily as an immunosuppressant. Several recommendations regarding therapeutic drug monitoring are also available for the use of everolimus-based immunosuppression regimens. However, everolimus use in oncology differs substantially, particularly because of the high doses involved. Therapeutic drug monitoring, although sometimes necessary, is not recommended as a routine in oncology. Thus, it was deemed inapplicable due to the lack of clear recommendations.

Case report

Here, we present a case where a patient was prescribed everolimus for renal cell carcinoma. The patient benefitted from a pharmaceutical consultation prior to treatment initiation, and a drug interaction with verapamil was suspected. Management and outcome: Therapeutic drug monitoring of everolimus was proposed. Based on the everolimus values reported in the literature, trough plasma concentration in the patient was greatly increased. The patient was then diagnosed with grade 4 oral mucositis, thereby requiring temporary suspension of everolimus treatment. Management of adverse effects was performed through multiple medicated mouthwashes.

Discussion

Therapeutic drug monitoring for everolimus is important for potential drug interactions or the occurrence of severe adverse events. In such cases, dose adjustments should be managed according to everolimus plasma concentrations. Clear oncological recommendations regarding plasma everolimus thresholds are required for a successful follow-up of the patient’s condition and to ensure adequate response to treatment.
A non-invasive method for quantitative monitoring of quality changes and water migration in bigeye tuna (Thunnus obesus) during simulated cold chain logistics using low-field nuclear magnetic resonance coupled with PCA
Authors: Wang Xin-Yun , Xie Jing , Qian Yun-Fang
Published: February 2020

Bigeye tuna ( Thunnus obesus) is an important fish species worldwide due to its desirable flavour and rich nutrition. Cold chain logistics is one of the most common methods to store and sell bigeye tuna ( Thunnus obesus). The purpose of this study was to investigate how bigeye tuna ( T. obesus) deteriorate during simulated cold chain logistics with fluctuating temperatures by monitoring the quality changes and water distribution. The physical and chemical results showed that the sensory score, texture profile analysis (TPA), and water holding capacity (WHC) decreased, while total volatile basic nitrogen (TVB-N), K value, aerobic plate counts (APC), and psychrotrophic bacterial counts increased with fluctuating temperatures during 132 h. Low-field nuclear magnetic resonance (LF-NMR) and magnetic resonance imaging (MRI) detection showed that the T21 (trapped water) and proton density decreased, while T22 (free water) decreased initially and then increased, indicating continuous water loss and water migration during storage. Principal component analysis (PCA) revealed that springiness, hardness, chewiness, T21, and sensory score were correlated with each other ( p < 0.05) and the linear combination of quality indicators and T2transverse relaxation time was established. Besides, temperature fluctuation (batch 3) accelerated the deterioration of bigeye tuna according to the comprehensive score of PCA. Results were based on LF-NMR which can be used to monitor quality changes in a fast non-invasive manner.
Impact of ADHD on Household Chores
Authors: Spaulding Sarah L. , Fruitman Kate , Rapoport Eli , Soled Derek , Adesman Andrew
Published: February 2020

Objective: To assess the relationship between ADHD and performance of household chores. Method: A 72-question online questionnaire was developed to collect demographic/clinical information as well as parents’ assessment of their child’s performance of self-care (SC) and family-care (FC) chores. Results: The sample consists of 797 primary caregivers of children with ADHD. The overwhelming majority of parents believed that ADHD to some extent affected their child’s ability to independently and satisfactorily complete SC and FC chores. An inverse relationship was noted between parent ratings of a child’s ability to do chores independently and satisfactorily and the likelihood they believed ADHD affected chore performance. There was no difference in chore performance between children with or without co-morbid oppositional defiant disorder. Conclusion: Given that household routines, including chores, play an important role in children’s development and psychosocial adjustment, clinicians must be sensitive to the adverse impact that ADHD may have in this regard.
From Eurovision to Asiavision: the Eurovision Asia Song Contest and negotiation of Australia’s cultural identities
Authors: Woods Denise
Published: February 2020

Australia’s participation in the Eurovision Song Contest and involvement in the organisation of the Asian version of Eurovision (the Eurovision Asia Song Contest) through broadcaster SBS has been celebrated, questioned and criticised. In this article, I examine Australia’s role in the organisation of the Eurovision Asia Song Contest in the context of Australia’s relationship with the region, and what this reveals about Australia’s cultural identity and place in this Asia-Pacific region. If Eurovision was conceived as a post-war project to unify Europe, I argue that for the Eurovision Asia Song Contest to become a reality, it needs to have a framework that takes into account the region’s own historical, political and geo-political contexts rather than having a Eurocentric model imposed on it.
High-temperature wettability study of mineral waste added CaO–CaF2–SiO2 and CaO–TiO2–SiO2-based electrode coating for offshore welds
Authors: Khan Waris Nawaz , Kumar Jagdish , Chhibber Rahul
Published: February 2020

This paper investigates the high-temperature wettability property of the mineral waste red ochre added CaO–CaF2–SiO2 and CaO–TiO2–SiO2-based electrode coating mixture for offshore welding. The extreme vertices design method was applied to formulate 21 coating compositions. The pellets made from developed electrode coating compositions were exposed to a high temperature of 1250℃ on the substrate of super duplex stainless steel of 2507 grade. The molten flux has been characterized for contact angle, surface tension, adhesion energy and spreadability. The regression analysis has been used to estimate the effect of individual components and their interactions on the wettability property parameters. The developed regression models have been optimized using multiresponse optimization to achieve optimum flux composition. Structural analysis of flux mixture has been done using X-ray diffraction and Fourier transformation spectroscopy.
Introduction: Normative orders and the remaking of Muslim spaces and selves in contemporary Russia
Authors: Di Puppo Lili , Schmoller Jesko
Published: February 2020

The aim of this special issue is to explore, from the perspective of various notions of space, the manifold ways in which Muslims in Russia live and practice their religion. We aim to analyse how Muslims in Russia are confronted in the practice of their religion with various conceptual and experiential realms. These realms correspond to certain divisions that they must negotiate and navigate. Examples of these include the boundaries between the secular and the religious; the public and the private; the official and the informal or unofficial; the local and the translocal/transregional/transnational; halal and haram, etc. Looking at Islam through the lens of space allows us to explore the dynamic ways in which Muslims in Russia have continued to creatively redefine, negotiate, reinforce, alter and dissolve these boundaries and divides since the fall of the Soviet Union. Diverse experiences and perceptions of Muslim spaces further help us to relate the question of the (re)appearance of these Muslim spaces to the process of de-secularisation that is currently taking place in post-Soviet Russia. In particular, we aim to clarify how the relationship between the secular realm and the Islamic religion is being reconfigured by examining how Muslim lives integrate, transcend and alter the normative dichotomies that are present in official discourses on Islam. We thus want to look ethnographically at the relationship between the ways in which normative categories define and delimit certain realms and the ways in which Muslims live their religion by creatively shaping and experiencing spaces that go beyond these normative divisions. In addition, this special issue explores the question of how the (re)creation of Muslim spaces is linked to processes of becoming Muslim, of cultivating a Muslim self and of experiencing different (but often simultaneous) identities and forms of personhood.
Adjusting the Knox test by accounting for spatio-temporal crime risk heterogeneity to analyse near-repeats
Authors: Briz-Redón Álvaro , Martínez-Ruiz Francisco , Montes Francisco
Published: February 2020

The near-repeat phenomenon usually occurs with any crime. Hence, to implement preventive measures, it is of great interest to figure out at which spatio-temporal scale crimes are more likely to be repeated by offenders. The Knox test is the most used statistical tool for evaluating the presence of the near-repeat phenomenon given a dataset of crimes that are located in space and time. The classic version of this test assumes that crime risk is homogeneous in both space and time, although this assumption rarely holds in reality. Therefore, the main goal of this article is to highlight the necessity of adjusting the standard version of the Knox test, including spatial and temporal effects that allow for the consideration of crime risk heterogeneity. In this regard, a methodology that has already been proposed for addressing this issue is described and adapted. This methodology is then put into practice through a dataset of burglaries recorded in the city of Valencia (Spain) in 2016 and 2017. The results yielded by both versions (standard and adjusted) of the Knox test confirm that the near-repeat phenomenon took place for the burglaries that occurred in Valencia during the period under investigation. However, using the adjusted version of the Knox test leads to a reduction in the number of spatio-temporal intervals that are declared as statistically significant. This fact should be born in mind before making decisions on preventive measures.
‘When it rains, it pours’: Housing evictions and criminal convictions in Sweden
Authors: Alm Susanne , Bäckman Olof
Published: February 2020

Precarious housing and criminal behaviour are both important elements in processes of marginalization and cumulative disadvantage. It is well known that housing eviction primarily affects the weakest groups in society. In this article we ask if housing eviction has an independent effect on subsequent criminality and if the effect varies across different types of crime (utilitarian, violent and drug crime). Using propensity score matching on administrative register data covering all housing evictions in Sweden 2009, linked with crime registers and registers containing other relevant background information, we find that eviction increases the conviction rates for all analysed crime types, utilitarian crime in particular.
Mean wind model for direct fire ballistics
Authors: Bober Tomas , Recchia Thomas
Published: February 2020

The depiction of wind used in modern system accuracy studies directly influences the design of precision-oriented weapon platforms. Therefore, the primary objective of the effort presented within was to develop a literature-supported definition of the battlefield wind environment relevant to direct fire combat engagements. This goal was accomplished by incorporating modern micrometeorological theory into the ballistic domain in order to define the mean wind along the flight path of a projectile. This information was then further leveraged to develop a description of the generic battlefield mean wind environment. The final portion of the effort compared the new and legacy wind models within a sample engagement scenario in order to quantify the differences between the two portrayals of atmospheric motion within the quasi-combat domain. The results of the work conducted indicate that the traditional view of wind tends to overestimate its contribution to the outcome of an engagement. While this single study does not completely invalidate the legacy approach to wind modeling in direct fire ballistics, it does warrant further investigation into the topic, as a more rigorous representation of atmospheric motion would ultimately lead to the production of more accurate weapon systems.
Community pharmacy–basedH. pyloriscreening for patients with uninvestigated dyspepsia
Authors: Papastergiou John , Donnelly Michelle , Yuen Terence , Li Wilson , van den Bemt Bart
Published: February 2020

Background:

Helicobacter pylori is identified by the World Health Organization as a major risk factor of gastritis, peptic ulcer disease and gastric carcinomas. As point-of-care screening technology becomes more widely available, pharmacists are ideally suited to use this tool to screen patients with H. pylori infection.

Purpose:

The objective of this study was to evaluate the feasibility of implementing point-of-care screening technology for H. pylori into community pharmacy practice and to assess the number of patients who are positively identified as a result of testing.

Methods:

Three pharmacies in Toronto, Ontario, offered H. pylori screening as part of their clinical programs. Pharmacists enrolled patients with symptoms of dyspepsia and/or receiving acid suppressant therapy for >6 weeks. Decision to screen was based on the Canadian Helicobacter Study Group Consensus (CHSG). Patients were screened using the Rapid Response H. pylori test.

Results:

Seventy-one patients were recruited, with a mean age of 46.3 years. Patients were ethnically diverse, with a significant proportion (59.2%) identified as being born outside of North America, including Asia (26.8%), Africa (9.9%), the Middle East (7%), Europe (9.9%) and South and Central America (5.6%). Overall, the detection rate of H. pylori infection was 21%. North Americans had the lowest incidence of an undiagnosed H. pylori infection (6.9%). Europeans (28.6%), Middle Easterners (20%) and Asians (21.1%) had a moderate incidence, followed by the highest prevalence in those of African descent (71.4%).

Conclusion:

These results highlight the readiness of community pharmacists to adopt H. pylori screening into practice and to leverage this novel technology to positively identify and treat undiagnosed H. pylori infection. Can Pharm J (Ott) 2020;153:xx-xx.
Personalizing the war: Perspectives for the adoption of news recommendation algorithms in the media coverage of the conflict in Eastern Ukraine
Authors: Makhortykh Mykola , Bastian Mariella
Published: February 2020

The use of algorithmically tailored individual news feeds is increasingly viewed as an important strategy for accommodating consumers’ information needs by legacy media. However, growing personalization of news distribution also raises normative concerns about the societal function of legacy media, in particular when dealing with personalization of traumatic and polarizing content. To extend the discussion of these concerns beyond the current focus on the role of news personalization in Western democracies, this article offers a conceptual assessment of perspectives for adopting personalization for conflict coverage in Ukraine and Russia, where media systems enjoy a lesser degree of press freedom. Using the coverage of the conflict in Eastern Ukraine as a case study, the article offers a conceptual framework for assessing the impact of personalization on the distribution of conflict-related news in a non-Western context.
Intraoperative Navigation and Cone Beam Computed Tomography for Restoring Orbital Dimensions: A Single-Center Experience
Authors: De Cuyper Brecht , Abeloos Johan , Swennen Gwen , Pottel Lies
Published: February 2020

Background:

Correction of post-traumatic orbital defects remains a challenge for the maxillofacial surgeon. We examined the added value of combined intraoperative (IO) navigation and IO cone beam computed tomography (CBCT).

Materials and Methods:

A retrospective cohort study was performed in all consecutive patients requiring unilateral post-traumatic orbital surgery between January 2012 and December 2018. Patients were divided into 3 groups: IO navigation (NAV), IO-CBCT (CBCT), and IO navigation with IO-CBCT (NAV-CBCT). A detailed description of our workflow is provided. Volumetric comparison of the operated orbit to the contralateral orbit was made with Brainlab.

Results:

Of the 81 cases, 22 patients were included (12 males/10 females) with a mean age of 51 years. Three patients were assigned to NAV, 6 to CBCT, and 13 to NAV-CBCT. The reconstructed orbital volume did not significantly differ from the contralateral orbital volume within the 3 groups. The mean difference between the contralateral and the operated orbit was 3.05 cm3, 3.72 cm3, and 1.47 cm3 for NAV, CBCT, and NAV-CBCT, respectively, where only NAV-CBCT showed a significant smaller volumetric difference in comparison to CBCT alone. Gender or age did not correlate with difference in orbital volume. Normal function and aesthetics was seen at 6 weeks postoperative in 0 of 3, 6of 6, and 6 of 13 patients of the NAV, CBCT, and NAV-CBCT, respectively.

Conclusion:

Orbital defects can be treated effectively using IO navigation. Although our data could not demonstrate a significant added value of IO-CBCT in cases where IO navigation was used based on volumetric difference alone, the combination of IO-CBCT and IO navigation seems to give the best results considering both volumetric difference and postoperative function and aesthetics. Confirmation in a prospective, randomized trial with a larger sample size is required.
Atrial arrhythmias in chronic lung disease‐associated pulmonary hypertension
Authors: Vahdatpour Cyrus A. , Luebbert Jeffrey J. , Palevsky Harold I.
Published: February 2020

Atrial arrhythmias are common during episodes of acute respiratory failure in patients with chronic lung disease‐associated pulmonary hypertension. Expert opinion suggests that management of atrial arrhythmias in patients with pulmonary hypertension should aim to restore sinus rhythm. This is clinically challenging in pulmonary hypertension patients with coexisting chronic lung disease, as there is controversy on the use of rhythm control agents; generally, in regard to either their pulmonary toxicity profile or the lack of evidence supporting their use. Rate control methods are largely focused on the use of beta blockers and calcium channel blockers. Concerns regarding their use involve their negative inotropic properties in cor pulmonale, the risk of bronchospasm associated with beta blockers, and the potential for ventilation/perfusion mismatching associated with calcium channel blockers. While digoxin has been associated with promising outcomes during acute right ventricular failure, there is limited evidence to suggest its routine use. Electrical cardioversion is associated with a high failure rate and it frequently requires multiple attempts. Radiofrequency catheter ablation is a more definitive approach, but concerns surrounding mechanical ventilation and sedation limit its applicability in decompensated pulmonary hypertension. Individual approaches are needed to address atrial arrhythmia management during acute episodes of respiratory failure.
Brands as a nation: An analysis of overseas media engagement of top Chinese brands
Authors: Chen Ouyang , Song Sonya , Yao Mike Z.
Published: February 2020

Exposure and engagement to the media coverage of Chinese brands among average consumers outside of the domestic Chinese market can serve as an important measure of China’s global influence. In this study, we analyzed the audience engagement of online articles about the top 20 Chinese brands from over 5000 web publishers around the world in a period of 5 months from October 2017 to February 2018. Specific results from our analyses point to a lack of sustained effort, careful coordination, and proper control in these companies’ public relations and crisis communication. The study also reveals a larger problem in China’s public diplomacy efforts. The top Chinese firms, despite their high market value, are yet to establish soft influence internationally. The global media engagements of Chinese companies are largely driven, passively, by special events and crises. Moreover, our study offers a new way of studying China and global media by leveraging large sets of industry data and adopting a set of audience matrices commonly used by media publishers to examine social science research questions.
Information Needs During Pregnancy and Its Associated Factors in Afghan Pregnant Migrant Women in Iran
Authors: Sharifi Mahnaz , Amiri-Farahani Leila , Haghani Shima , Hasanpoor-Azghady Syedeh Batool
Published: February 2020

Background: Access to pregnancy-related information is an important requirement for all pregnant women, especially women at risk, such as immigrants. Regarding this, the present study was conducted to determine the information needs during pregnancy and its associated factors in the Afghan pregnant women. Methods: This cross-sectional study was conducted on 280 Afghan pregnant women who received care at the prenatal clinics of selected health care centers in the southeast of Tehran in 2018. The study population was selected using the continuous sampling method. The sampling was performed through the continuous sampling method from all the Afghan pregnant women who received care at the prenatal health centers of the southeast of Tehran. Results: Among the information needs during pregnancy, the fetal (83.34 ± 20.65) and smoking (62.61 ± 28.88) domains had the highest and lowest mean scores by percentage, respectively. The information needs during pregnancy showed a statistically significant relationship with age, women’s education level, husband’s education level, duration of living in Iran, place of residence, insurance status, number of children, place of the previous delivery, and routine prenatal care. Based on the multiple regression model, only the place of birth and place of residence accounted for 19% of information needs during pregnancy. Conclusion: As the findings indicated, the prenatal care–related education should address the domains that are unknown for Afghan women. Furthermore, in this education, the demographic and reproductive characteristics of the recipients should be taken into account to improve the pregnancy outcome among this population.
Total knee arthroplasty reduces the risk of mortality in osteoarthritis patients up to 12 years: A Korean national cohort longitudinal follow-up study
Authors: Choi Hyo Geun , Kwon Bong Cheol , Kim Joong Il , Lee Joon Kyu
Published: February 2020

Introduction:

Mortality rates and causes of death after total knee arthroplasty (TKA) are of great interest to surgeons. However, there is a shortage of studies regarding those of the Asian population. The aim of this study was to compare the mortality rate and causes of death in patients after TKA to the general population.

Methods:

National sample cohort data from the Korean Health Insurance Review and Assessment Service were used. In this study, 1:4 matched patients after TKA (TKA group: 5072) and general participants (control group: 20,288) were selected as subjects. Their average follow-up duration was 57.2 months ranging from a year up to 12 years. The matches were processed for age, gender, income, region of residence, and past medical history. Mortality rates and causes of death were compared between groups. Regarding the mortality rates, we also performed subgroup analyses according to age.

Results:

Adjusted hazard ratio (HR) of the TKA group for mortality rate was less than 1 with significance (adjusted HR = 0.61 (95% confidence interval = 0.54–0.70, p < 0.001)). The ratios were less than 1 for both age groups (<70 and ≥70 years), respectively; however, for patients under 70, they were insignificant. Among the 11 major causes of death, the circulatory disease showed the most significantly reduced mortality rate for the TKA group compared to the control group. The neoplasm was the only other cause with a significantly reduced mortality rate for the TKA group.

Conclusion:

The mortality rate in the TKA group was significantly lower than in the control group up to 12 years after the surgery in Korea. Among the major causes of death, circulatory disease and neoplasm showed a significant reduction in the mortality rate of the TKA group compared with the control group.