bluuebunny/crossref_metadata_2025 huggingface dataset:
ИДЕНТИФИКАЦИЯ SNP-ПРОФИЛЕЙ И ОЦЕНКА ПЛЕМЕННОЙ ЦЕННОСТИ СКОТА КАЛМЫЦКОЙ ПОРОДЫ С ИСПОЛЬЗОВАНИЕМ БИОЧИПОВ
Authors: И.Ф. Горлов , А.В. Ранделин , М.И. Сложенкина , А.К. Натыров , Б.К. Болаев , О.А. Княжеченко , Д.А. Мосолова
Published: December 2024

At present, the improvement and rational use of Kalmyk cattle is an urgent task to intensify Russian animal husbandry. The article presents the data on the results of the fullgenome analysis of Kalmyk livestock populations grown at the “Plodovitoye” agricultural production cooperative in the Republic of Kalmykia. Based on the results of the research, it is possible to assess the accuracy of the distribution of animals in the lines and select further breeding strategy and prospects for using intraline selection. Also, in order to analyze the genes that characterize the most important economically useful traits to be formed, i.e., the early maturity and widebody steers of the Kalmyk breed, a genomic analysis has been carried out. According to the results of the analysis conducted, three SNPs associated with the body weight have been identified, with the significance level being above the threshold. So, the Hapmap46744BTA03982 was associated with cellular processes such as growth, signalling and gene regulation; the ARSBFGLNGS12917 SNP function influenced cellular processes, and the protein encoded by the LOC787924 gene affected the catalysis and synthesis of diacylglycerol from monoglycerides and fatty acids and, therefore, contributed to the formation of the key role in the absorption of fatty acids by the body. Also as a result of the fullgenome analysis, there have been identified two SNPs associated with the animal size being formed. Thus, it can be concluded that the SNPs studied are directly related to the formation and development of body cells. The research results contribute to the deepening and expansion of modern knowledge of the economic and biological traits of the oldest Russian Kalmyk meat breed of cattle and its genealogical structure.
МЯСНЫЕ КАЧЕСТВА ЯПОНСКОГО ПЕРЕПЕЛА ПРИ ВВЕДЕНИИ в РАЦИОН ПРОДУКТОВ ЖИЗНЕДЕЯТЕЛЬНОСТИ БОЛЬШОЙ ВОСКОВОЙ МОЛИ (Galleria melonella)
Authors: САКОВЦЕВА Т.В. , ВОЙНОВА О.А. , КСЕНОФОНТОВА А.А. , КСЕНОФОНТОВ Д.А. , САВЧУК С.В. , СЕРГЕЕНКОВА Н.А.
Published: December 2024

Цель исследования состояла в оценке влияния продуктов жизнедеятельности большой восковой моли на качество мяса японского перепела. Лабораторные исследования мяса проводили по общепринятым методикам. По результатам исследования установлено, что изучаемая кормовая добавка в дозировке 1-2% оказала положительное влияние на некоторые качественные показатели мяса перепелов.

The aim of the study was to assess the impact of the products of the large wax moth on the quality of Japanese quail meat. Laboratory tests of meat were carried out according to generally accepted methods. According to the results of the study, it was found that the studied feed additive in a dosage of 1-2% had a positive effect on some quality indicators of quail meat.
ЗООТЕХНИЧЕСКИЕ ПОКАЗАТЕЛИ ЧИСТОПОРОДНОГО И ПОМЕСНОГО МОЛОДНЯКА КРС В РАВНИННОЙ ПРОВИНЦИИ ДАГЕСТАНА
Authors: Садыков М.М. , Алиханов М.П. , Алигазиева П.А. , Симонов Г.А.
Published: December 2024

Изучены продуктивные и экстерьерные показатели чистопородных и помесных бычков, полученных от скрещивания коров красной степной породы с казахской белоголовой в равнинной провинции Республики Дагестан. Подопытных бычков выращивали по технологии мясного скотоводства «корова-теленок». Установлено, что помесный молодняк к отъему достиг живой массы больше на 22,4 кг или на 11,9% больше, чем аналоги материнской породы. В 12-месячном возрасте помесные бычки имели живую массу 291,8 кг, аналоги 263,8 кг, что больше аналогов красной степной породы на 28 кг или 10,6% и характеризовались хорошо выраженными мясными формами. В 18 месячном возрасте живая масса помесных бычков составила 436,6 кг, чистопородных - 390 кг соответственно, и они превосходили аналогов на 45,8 кг или 11,7% при достоверной разнице (Р<0,001). Среднесуточные приросты помесного молодняка за весь период выращивания были выше на 12% по сравнению с чистопородными аналогами. Помесные бычки также имели достоверные различия в высотных и широтных промерах (Р<0,01, Р< 0,001).

The productive and exterior indicators of purebred and crossbred steers obtained from crossing red steppe cows with Kazakh white-headed bulls in the plain province of the Republic of Dagestan were studied. The experimental steers were raised using the cow-calf technology of beef cattle breeding. It was found that the crossbreed young reached a live weight of 22.4 kg or 11.9% more than the analogues of the parent breed. At 12 months of age, crossbred gobies had a live weight of 291.8 kg, analogues-263.8 kg, which is more than the analogues of the red steppe breed by 28 kg or 10.6% and were characterized by well-defined meat forms. At 18 months of age, the live weight of crossbred bulls was 436.6 kg, purebred-390 kg, respectively, and exceeded the analogues by 45.8 kg or 11.7% with a significant difference (P<0.001). The average daily growth of crossbred young animals over the entire growing period was 12% higher compared to their purebred counterparts. The crossed gobies also had significant differences in height and latitude measurements (P<0.01, P<0.001).
ПРИВЕДЁННАЯ ТОЛЩИНА КОМПОЗИТНОЙ МОДЕЛИ ЛЕДЯНОГО ПОКРОВА, СОСТАВЛЕННОЙ ИЗ НЕСКОЛЬКИХ СЛОЁВ ГРАНУЛ СФЕРИЧЕСКОЙ ФОРМЫ
Authors: СЕБИН А С. , БЛИНОВ К Д. , ДВОЙЧЕНКО Ю А. , КУРКИН А А.
Published: December 2024

Использование композитной модели ледяного покрова (GP-ice), получаемой замораживанием во льду опытового бассейна полиэтиленовых гранул, позволяет уменьшить энергетические затраты на разрушение модельного льда, что необходимо для выполнения условий моделирования при испытаниях моделей ледоколов. Одной из проблем при этом является определение толщины льда разрушаемого моделью судна. Рассматривается использование гранул сферической формы разного диаметра, их однослойное и многослойное замораживание. Получены теоретические зависимости приведенной толщины композитной модели ледяного покрова для разных условий компоновки гранул их диаметра и глубины проморозки. Приведены графики результатов расчетов. Представлены результаты экспериментов по определению приведенной толщины методом гидростатического взвешивания. Дано устройство экспериментальной установки, порядок проведения опытов. Результаты экспериментов сопоставлены с теоретическими расчетами. Делается вывод о возможности использовать непосредственное измерение толщины намороженного слоя пресноводного льда измерительным инструментом для оценки приведенной толщины.

The use of GP-ice model of the ice cover obtained by freezing polyethylene granules in the ice of the towing tank makes it possible to reduce the energy costs of breaking model ice, which is necessary to meet the modeling conditions when testing icebreaker models. One of the problems in this case is to determine the thickness of the ice destroyed by the ship model. The use of spherical granules of different diameters, their single-layer and multi-layer freezing is considered. Theoretical dependences of the equivalent thickness of the composite model of the ice cover for different conditions of the arrangement of granules of their diameter and depth offreezing are obtained. Graphs of the calculation results are given. The results of experiments to determine the equivalent thickness by hydrostatic weighing are presented. The device of the experimental setup and the procedure for conducting experiments are given. The experimental results are compared with theoretical calculations. It is concluded that it is possible to use a direct measurement of the thickness of the frozen layer offreshwater ice with a measuring instrument to estimate the equivalent thickness.
indexGIXS – software for visualizing and interactive indexing of grazing-incidence scattering data
Authors: Smilgies Detlef-M. , Li Ruipeng
Published: December 2024

Grazing incidence small- and wide-angle scattering (GISAXS, GIWAXS) are widely applied for the study of organic thin films, be it for the characterization of nanostructured morphologies in block copolymers, nanocomposites, or nanoparticle assemblies, or the packing and orientation of small aromatic molecules and conjugated polymers. Organic thin films typically are uniaxial powders, with specific crystallographic planes oriented parallel to the substrate surface. The associated fiber texture scattering patterns are complicated by refraction corrections and multiple scattering. We present an interactive graphics tool to index such patterns.
New class of fluorogenic probes for antigens based on DARPin-silicon pyronine conjugates
Authors: Nakadate Mamiko , Kojima Ryosuke , Seike Naoki , Tachibana Ryo , Fujita Kyohhei , Kamiya Mako , Plückthun Andreas , Urano Yasuteru
Published: December 2024

Fluorogenic probes for antigens are useful for various purposes, including medical diagnostics and imaging, but achieving a rapid, large fluorescence increase is difficult. Here, we report a new class of fluorogenic probes for antigens based on a conjugate of an antibody-mimetic DARPin bearing a site-specifically incorporated cysteine and silicon-pyronine (SiP), which reacts reversibly with thiols. By using a library-screening approach, we found that the absorbance and fluorescence of SiP conjugated to a DARPin are quenched by an addition reaction of the cysteine installed in the DARPin to SiP, and the equilibrium of this reaction is shifted to dissociation by antigen binding, leading to rapid, large increases of absorption and fluorescence. As a proof of concept of this chemical design principle, we constructed fluorogenic probes targeting GFP and EpCAM, which showed 25- and 12-fold fluorescence increases upon binding, respectively. The latter probe enabled wash-free cancer cell imaging with a low background.
Electrochemical Dissolution: Paths in High-Entropy Alloy Composition Space
Authors: Plenge Mads K. , Pedersen Jack K. , Cipriano Luis A. , Rossmeisl Jan
Published: December 2024

The stability of a nanoparticle catalyst during electrochemical reaction is crucial for its application. Despite increasing interest in multi-metallic alloy nanoparticles, such as high-entropy alloys (HEAs), for electrocatalysis and emerging models for their catalytic activity, there is limited work on frameworks that can predict the metastability of these alloys under reaction conditions, including stability against electrochemical surface dissolution. Incorporating electrochemical stability in multi-objective optimization would advance HEAs as a catalyst discovery platform. To address the knowledge gap on electrochemical stability, we propose a methodology for simulating the dissolution of n-element alloy nanoparticles comprised of density functional theory and machine learning regression to calculate the dissolution potentials of the surface atoms. We demonstrate the methodology for the Ag-Au-Cu-Ir-Pd-Pt-Rh-Ru HEA system with the conditions of the oxygen reduction reaction. We investigated trends in stability against dissolution through a compositional grid search for the octo-metallic composition space, uncovering two alloying strategies to increase stability against electrochemical surface dissolution: Alloying with a noble metal or a metal with high relative surface energy. In the simulations, stabilization ensues from forming a protective surface layer, and consequently, the dissolution of persistent alloyed nanoparticles results in core-shell structures. The model enables tracing the evolution of the surface and dissolved composition during electrochemical dissolution, forming paths of dissolution and revealing unretainable surface compositions.
Preparative [3+2] cycloaddition of CH2N2 to acrylate derivatives: revising, scope and synthetic applications
Authors: Shuvakin Serhii , Ivonin Sergiy , Pendyukh Vyacheslav , Pashenko Olexandr , Shishkina Svitlana , Kozytskiy Andriy , Rozhenko Alexander , Manthe Uwe , Spengler Tobias , Volochnyuk Dmytro , Ryabukhin Serhiy
Published: December 2024

Safe and preparative approaches using flow chemistry technologies were applied to the known [3+2] cycloaddition of diazomethane with a diverse set of substituted methyl acrylates. The initially formed Δ¹-pyrazolines were also subjected to in-flow transformations. DFT modelling of the [3+2] cycloaddition predicts a concerted asynchronous mechanism for the reaction. The observed in the experiment regio- and stereoselectivity of the transformation are kinetically driven. Some of the initially formed Δ1-pyrazolines tend to isomerize spontaneously to Δ2-isomers. However, conditions suitable for isolating Δ¹-pyrazolines, previously considered unstable, have been discovered. Other [3+2] cycloaddition products were found to be stable on isolation and storage. By treatment of the formed Δ1-pyrazolines with strong acid (HCl), hydrochlorides of isomeric Δ2-pyrazolines have been isolated. Photo-induced nitrogen elimination from Δ1-pyrazolines in the flow photo reactor provides an easy approach for the preparative synthesis of a broad series of cyclopropanes, which are valuable motifs in pharmaceuticals and agrochemicals. The reaction proceeds under mild conditions with preservation of configuration of stereocenters. All the reactions are easily scalable at least up to several tens of grams. This work demonstrates that a deep mechanistic understanding of the reaction pathways, combined with the advantages of flow chemistry and photochemical techniques, can transform a classic reaction into a practical and scalable synthetic methodology.
Investigating the compatibility of polymerase chain reaction and oligonucleotide ligation assay for one step detection of point mutations
Authors: Chauhan Ayushi , Toley Bhushan
Published: December 2024

We present a systematic optimization of the components of polymerase chain reaction (PCR) and oligonucleotide ligation assay (OLA) to combine them into a one-pot reaction. Such a one-pot reaction would enable the simultaneous amplification of a target nucleic acid sequence via PCR (for species identification) and the detection of a point mutation within that sequence via OLA (for the determination of antimicrobial resistance). The results can be visualized directly on a lateral flow assay without additional equipment. Specifically, here, we amplify a 163 bp region of the rpoB gene of Mycobacterium tuberculosis and detect the 531 mutation therein. The concentrations of each component of PCR and OLA buffer were optimized to design a new buffer compatible with the combined reaction. An important finding of the study is that the performance of PCR and OLA is highly sensitive to magnesium ion (Mg2+) concentration, and the incompatibility in the Mg2+ concentration is preventing the integration of the two reactions in the present study. Using a DNA polymerase that can tolerate high Mg2+ concentration might lead to the successful integration of PCR and OLA. Compared to the existing methods of conducting the PCR and OLA reaction sequentially, the one-pot reaction would significantly reduce the reaction time, user intervention, and plausible risk of amplicon contamination arising from opening the PCR tubes.
Flow electroreductive nickel-catalyzed cyclopropanation of alkenes using gem-dichloroalkanes
Authors: Regnier Morgan , Vega Clara , Ioannou Dimitris , Zhang Zhenyu , Noel Timothy
Published: December 2024

Cyclopropanes are valuable motifs in organic synthesis, widely featured in pharmaceuticals and functional materials. Herein, we report an efficient electrochemical methodology for the cyclopropanation of alkenes, leveraging a nickel-catalyzed process in continuous-flow. The developed protocol demonstrates broad substrate scope, accommodating both electron-rich and electron-poor alkenes with high functional group tolerance. Beyond dichloromethane as a feedstock methylene source, the methodology enables the synthesis of methylated, deuterated, and chloro-substituted cyclopropanes. Mechanistic investigations suggest the electro-generation of a nickel carbene as key intermediate. Notably, the reaction operates under ambient conditions, tolerates air and moisture, and achieves scalability through continuous-flow technology, offering a straightforward route to multi-gram quantities with enhanced throughput.
Diseño de una herramienta de apoyo para la selección de tecnologías de AIDC en procesos logísticos
Authors: Ríos Córdova María Alejandra , Lopes-Martínez Igor , Alemán Bravo Roxana
Published: December 2024

En las cadenas de suministro actuales, el uso de las tecnologías de identificación y captura automática de datos (AIDC) permite que la información que fluya sea estandarizada y fiable, así como obtener una serie de ventajas relacionadas con ahorro de tiempo y costos. En Cuba, el uso de estas tecnologías no se encuentra regulado en las leyes nacionales y las empresas, en su mayoría, no las utilizan, se considera que a causa del desconocimiento de su efectividad. En esta investigación se analizan las tecnologías AIDC: específicamente los sistemas de códigos de barras y los sistemas de radiofrecuencia, su funcionamiento y beneficios de su utilización en las cadenas suministro. A partir de la necesidad existente, se diseñó una herramienta basada en un procedimiento que establece una guía para la selección de tecnologías que se pueden implementar en procesos logísticos. Se emplea la herramienta diseñada para casos de estudio a fin de conocer su aplicación y modo de uso.
La manufactura aditiva como elemento imprescindible de la industria 4.0 en beneficio de la ingeniería: un análisis bibliométrico
Authors: Díaz-Martínez Marco Antonio , Román-Salinas Reina Verónica , Ruíz-Hernández Santos , Hernández-Cortés Nicolás Alberto , González-Rubín Vania Iraís
Published: December 2024

La manufactura aditiva, fundamental en la industria 4.0, transforma la producción creando objetos tridimensionales mediante capas sucesivas. Esta tecnología ofrece flexibilidad de diseño y eficiencia en el uso de materiales, pero enfrenta retos en la optimización de procesos para asegurar calidad y precisión. Su integración con la industria 4.0 plantea desafíos como la interoperabilidad de sistemas CAD, la gestión de datos y la ciberseguridad. A pesar de estos desafíos, permite crear geometrías complejas, reducir el consumo de materias primas y mejorar las propiedades de los productos finales. La investigación en materiales y procesos acelera su adopción, promoviendo modelos de negocio personalizados, sostenibles y descentralizados. Este enfoque está revolucionando la producción industrial y doméstica, y remodelará los modelos de negocio y diseño de productos. En la investigación, se revisaron 257 documentos, excluyéndose 172, y se examinaron 85 textos con el software MAXQDA v.2020 para el análisis bibliométrico.
Simulador de luz artificial para paneles solares: diseño y construcción en el Perú
Authors: Fernández Goicochea William Fernando , Carbajal Ccoyllo Mario Dayvid
Published: December 2024

El objetivo de esta investigación fue diseñar y construir una máquina de luz artificial que simule las iluminaciones solares de la costa, sierra y selva del Perú, evaluando su impacto en los paneles solares. La metodología comprendió la construcción de la máquina en la Universidad de Lima y pruebas con un módulo compuesto por una fuente de luz artificial, un panel solar, un módulo de medición y una pinza amperimétrica. Se realizaron ensayos variando la iluminación para simular las condiciones de las distintas regiones del Perú. Los resultados obtenidos fueron 4,8, 7,2 y 4,0 kWh/m² para las simulaciones de costa, sierra y selva, respectivamente. La investigación concluyó que es factible desarrollar una fuente de iluminación solar que mejore la eficiencia de los paneles solares y permita trabajar en condiciones estacionarias. Sin embargo, es necesario aumentar los ensayos y mejorar su precisión para una evaluación más objetiva de su utilidad práctica.
Obtención de celobiosa a partir de la hidrólisis enzimática parcial de la celulosa de cáscara de arroz
Authors: Ayala Armijos Humberto , Romero Calle Nicole , Madrid Celi Braulio , Quezada Sarmiento Ramiro , Tinoco Galvez Edgar , Chavez Abad Richard
Published: December 2024

El objetivo de la investigación fue ablandar la cáscara de arroz mediante pretratamientos hidrotérmicos y alcalinos. Se aplicó temperatura a 121 °C por tres lapsos de tiempo (15, 30 y 45 minutos) y con NaOH en tres concentraciones (0,5, 1 y 1,5 %); se agitó a 120 rpm por una hora; para ajustar a pH 4,8 se adicionó HCl al 20 %, y se añadió 30 FPU de la enzima β-glucosidasa; se agitó a 120 rpm a 50 °C durante 144 horas. La aplicación de 121 °C durante 45 minutos logró un 34,62 ± 0,79 % de hidrólisis parcial de celulosa a celobiosa y 18,14 ± 0,09 % de hidrólisis total de celulosa a glucosa; y en los hidrolizados donde se pretrató con hidróxido de sodio al 1,5 %, se alcanzó 8,39 ± 0,79 % de celobiosa y 46,64 ± 0,30 % de glucosa. La aplicación de pretratamiento hidrotérmico favorece la hidrólisis parcial de la celulosa a celobiosa.
Russian School of Electoral Studies: Methodological Approaches
Authors:   Petrozavodsk State University, Rozhneva S. S.
Published: December 2024

This article focuses on the importance of studying electoral practices, voting behavior and preferences, and value aspects of voters' political culture manifested in elections. Attention is drawn to the process of institutionalization of Russia's social science in the field of studying electoral processes, which specifies the goal of the paper – to determine the stages of Russian school of electoral studies formation, to analyze their theoretical and methodological specifics. The article presents the author's approach to four-stage periodization: 1905-1917 – the pre-revolutionary period of journalistic research with a predominance of statistical methods of data processing; 1960s – 1980s – the Soviet period of research with criticism of Western electoral concepts of political participation and behavior based on scientific communism and Marxist-Leninist ideological orientation; 1989-1990s. – the beginning of the formation of Russian electoral studies methodology, professionalization and institutionalization of scientific knowledge; 2000s – present – independence of the Russian school of multi-paradigm, cross-disciplinary electoral research, which is explained by the specific nature of electoral studies performed by Russian scientists. In conclusion, the author highlights the fact that at the present stage there is an increasing complexity of the Russian electoral studies methodology – from qualitative, descriptive methods to quantitative mathematical processing of a large pool of data. This fact helps to identify indicators for calculating the structure of voting behavior and preferences, to determine parameters for comparison, to model regional and local voting practices, etc.
“God Gives the Poor Herbs and Fungi to Mend the Ailments”: Traditional Medicine, Indigenous Care, and the Fungal Novel
Authors: Jara Victoria
Published: December 2024

In this article I establish that there is a nascent interest in Latin American writers to represent the versatility of fungi. I conduct an in-depth analysis of the Mexican novel Brujas [Witches] (2020) by Brenda Lozano from a feminist political ecology viewpoint (Arriagada Oyarzún and Zambra Álvarez, 2019), focusing on the representation of the role of fungi in Indigenous medicine and care within Mexico. My theoretical framework is informed by feminist theorizations on care (Tronto 1993; Puig de la Bellcasa 2017; The Care Collective 2020), decolonial perspectives of climate degradation (Svampa and Viale 2014; Gudynas 2011, 2015, 2016), and Indigenous systems of knowledge and medicine. After introducing the history of Indigenous biomedical history in Latin America, I examine the crucial role of fungi in the novel as agents of gender, race, socio-political resistance, and resilience. I conclude  by proposing the categories of mycophilic (fungus-loving) and mycophobic (fungus-fearing) fungal novels.
Relación entre ansiedad y consumo de alcohol en médicos residentes: estudio transversal en un hospital general de zona de la región centro-sur de México
Authors: Melgarejo-Vásquez Manuel Eduardo , Trujillo-Osorio Sergio Alejandro , Arévalo-Ramírez Minou Del Carmen
Published: December 2024

Objetivo: Este estudio explora la relación entre síntomas de ansiedad y consumo de alcohol en médicos residentes del Hospital General de Zona Número 20 “La Margarita” del Instituto Mexicano del Seguro Social, ubicado en Puebla, México, dentro de la Región Centro-Sur, con el propósito de mejorar su salud mental y bienestar. Material y métodos: Se realizó un estudio observacional en 106 médicos residentes de 25 a 32 años. Se emplearon los cuestionarios GAD-7 y AUDIT para medir ansiedad y consumo de alcohol. El análisis incluyó una correlación de Spearman con SPSS v25. Resultados: El 54.7% presentó ansiedad moderada-severa y el 55.6% consumo de alcohol de riesgo. La correlación fue positiva y significativa (r = 0.862, p < 0.001), sugiriendo una relación entre ambas. Conclusiones: Se observa una alta prevalencia de ansiedad y consumo de alcohol, lo que señala la urgencia de fortalecer programas de apoyo en las instituciones de salud. Se sugieren estudios longitudinales.
Palabras clave: Ansiedad; Consumo de Bebidas Alcohólicas; Cuerpo Médico de Hospitales; Cuestionario de Salud del Paciente
Stabilizing Tensor Voting for 3D Curvature Estimation
Authors: Alfaro Pérez Victor , Uhlmann Virginie , Forster-Heinlein Brigitte
Published: December 2024

Curvature plays an important role in the function of biological membranes, and is therefore a readout of interest in microscopy data. The PyCurv library established itself as a valuable tool for curvature estimation in 3D microscopy images. However, in noisy images, the method exhibits visible instabilities, which are not captured by the standard error measures. In this article, we investigate the source of these instabilities, provide ade- quate measures to detect them, and introduce a novel post-processing step which corrects the errors. We illustrate the robustness of our enhanced method over various noise regimes and demonstrate that with our orientation correcting post-processing step, the PyCurv library becomes a truly stable tool for curvature quantification.
Convolutional Neural Networks Application for an Average Thermodynamic Characteristics Calculation of Spin Glasses
Authors: Kapitan Dmitrii , Andriushchenko Petr , Nefedev Konstantin , Kapitan Vitalii
Published: December 2024

In this work, we introduce a novel methodology for studying the low-temperature phase

of frustrated spin glass models using convolutional neural networks (CNNs). Our approach addresses the regression of thermodynamic properties, specifically the average energy ⟨E⟩, as a function of temperature T for spin glasses on a square lattice. By modelling the spin glass as a weighted graph, where exchange interaction values Jk are represented by the edges and mapped to lattice coordinates, we explore the functional relationship between ⟨E⟩ and the spatial distribution of J. We evaluate CNNs for their performance across various spin glass sizes and distributions of exchange integrals, demonstrating the potential of CNNs in capturing complex spin interactions and advancing the understanding of frustrated systems.
Interactive Software for Simulation of Oxygen Transport from Capillaries to Brain Tissue of Preterm Infants
Authors: Kovtanyuk Andrey , Sidorenko Irina , Park Nikolai , Lampe Renée
Published: December 2024

The paper presents a description of a computational algorithm and applied software designed to find the partial pressure of oxygen in a model domain known as the Krogh cylinder. The algorithm is implemented using the finite element method in the FreeFEM package, the graphical interface is made using Python language. The developed software is adapted for calculating partial pressure of oxygen in the brain tissue of preterm infants.
Trade-Offs in Robust Trajectory Optimization Based on Sensitivity Minimization
Authors: Akman Tugba , Holzapfel Florian
Published: December 2024

Rapid developments in aerospace technologies demand reliable procedures to plan ro- bust missions with high safety. To increase safety under uncertainties in model parameters or environmental conditions, multi-objective robust optimization methods via sensitivity minimization can be used. An acceptable trade-off between a nominal operational cost (e.g., time, energy) and robustness is searched for to plan missions that are less prone to disturbances. The presented analysis considers open-loop and closed-loop sensitivity min- imization approaches and utilizes multi-objective optimization to assess the performance and the limitations of both approaches. To solve the multi-objective optimization prob- lems, scalarization techniques are employed using weighted sums and cost bounds. By varying weights and cost bounds, multiple optima can be calculated, resulting in an ap- proximate Pareto front and giving rise to an overview of the trade-off between optimality and robustness of the solutions. The analysis is performed for robust unmanned aerial vehicle (UAV) trajectory optimization minimizing positional sensitivities.
Phoenix-OC: Applied Optimal Control using Advanced Structure Exploitation and Multi-Level Parallelism
Authors: Diepolder Johannes
Published: December 2024

This paper introduces Phoenix-OC, a novel optimal control software for the solution of large-scale, multi-phase Optimal Control (OC) problems. Phoenix-OC employs segmented collocation methods for the state discretization and B-Splines for the control parameteriza- tion. Each of the parameterized controls is allowed to have a distinct degree and knot grid. Additionally, control derivatives of arbitrary order can be utilized in the model, as well as constraint and cost functions. User-defined functions can be modeled either through an automatic differentiation framework or via a generic C interface supporting the utilization of virtually arbitrary functions, external models, etc. Among other features, the software inherently supports table data interpolation, the computation of post-optimal sensitivities for parametric OC problems, bi-level optimization, homotopy formulations, parallel batch runs, and job dependencies. Furthermore, jobs can be executed locally or through a job scheduler on computer clusters.

Phoenix-OC operates on the Phoenix-CORE engine - a generic sparse evaluation frame- work for both the evaluation and derivative computation of vector-valued functions. Cen- tral to this computational engine is the notion of an Extended Sparsity Pattern (ESP). This novel type of sparsity pattern extends traditional binary-valued sparsity patterns to a new type of floating-point pattern, allowing for advanced structure exploitation. The ex- ploitation of sparse structures based on the ESP, combined with the multi-level parallelism implemented in Phoenix-OC, yields high performance across a range of representative benchmarks from engineering applications.
Linear Differential Games with Multi-Dimensional Terminal Target Set: Geometric Approach
Authors: Mikhailov Anton , Kumkov Sergey
Published: December 2024

The paper deals with linear differential games with a fixed terminal instant, convex geometric constraints of the players’ controls, and convex terminal target set. The first player tries to guide the system to the target set at the terminal instant, the second one hinders this. In the 1960’s, L. S. Pontryagin proposed a theoretic geometric procedure for approximate constructing time sections of the maximal stable bridge for games of this type. This procedure is known as the second Pontryagin’s method. At the beginning of the 1980’s in the Krasovskii Institute of Mathematics and Mechanics (Yekaterinburg, Rus- sia), a computational algorithm for the procedure has been suggested and implemented as a computer program. However, this algorithm is suitable only for games with two- dimensional equivalent phase vector. The authors suggest a procedure suitable for games with a multi-dimensional phase vector. For an implementation of this method, one needs implementations of convex hull construction, Minkowski sum and difference. The authors have taken known algorithms for convex hull construction and Minkowski sum. An al- gorithm for Minkowski difference as well as some procedures for conversion of different representations of multi-dimensional polytopes to each other have been suggested. All these algorithms have been implemented as a computer library in C# by the authors. A series of model differential games has been computed.
Priorities of innovative development of the industrial complex of the regions
Authors: Kurasov Mihail
Published: December 2024

The innovative development of industry is one of the priorities of the long-term development of the Russian Federation to ensure the competitiveness of the Russian economy and technological sovereignty. The active development and implementation of innovative tools, forms and methods of industrial development into the practice of economic activity is becoming a priority in modern conditions. This circumstance proves the relevance of the research topic. Based on the analysis of the dynamics of innovative forms of development of the industrial sector – clear priorities - we have formed a concept for managing the innovative development of the industrial complex of the region (using the example of the Kursk region).
Increased productivity through introducing the gamification tools into the staff motivation system
Authors: Sysoeva Elena , Sazonova Elizaveta , Mal'ceva Irina
Published: December 2024

One of the most important factors determining competitiveness, economic growth, wealth and standard of living of the population is labor productivity, therefore, the search for new mechanisms and tools to improve it is an urgent research task. With the development of technology and the digital transformation of business processes, the ways of motivation are also changing. Differences in the perception of information by representatives of different generations force employers to look for ways that allow them to motivate employees most effectively. This is especially important in conditions of personnel shortage and high competition for qualified personnel.
The article examines various theories of generations, as well as their relationship with the stages of technological structures, and provides an analysis of studies revealing the structure of career motivation of employees of different generations. Generational values and needs are presented, and gamification tools that contribute to the growth of employee productivity are proposed, also the attitude of representatives of different generations to the introduction of robotic systems and artificial intelligence technologies is analyzed.
METHODOLOGICAL APPROACH TO INTEGRATED ASSESS-MENT PARAMETERS OF THE EFFECTIVENESS OF STAKEHOLDER INTERACTION IN THE DIGITAL ENVIRONMENT TO IMPROVE THE DEVELOPMENT STRATEGY A SINGLE-INDUSTRY MUNICIPALITY
Authors: Garipova Venera
Published: December 2024

The scientific article reveals the features of improving the strategy of socio-economic development of municipalities. The role of the digital eco-environment for stimulating the development opportunities of a single-industry municipal territory in the context of key determinants is revealed. The characteristics of promising forms of stakeholder interaction in the digital eco-environment of a single-industry municipality are presented and their leading groups are highlighted. The author's vision regarding the formation of a range of analytical indicators that can be ap-plied in order to assess the effectiveness of stakeholders' activities in the digital eco-environment of the territory is revealed. Special attention is paid to promising aspects of the digital development of single-industry municipal formations, which take into account current challenges and opportunities for qualitative transformations of conditions for living citizens, as they are aimed at improving the quali-ty and standard of living of citizens. The conclusion is made about the special importance of taking into account the opinion of stakeholders to improve the stages of goal-setting at all stages of the implementation of the strategy of socio-economic development of territories at the municipal level.
Economic security of the tourism and recreation sector: essence and economic content
Authors: Umerov Veli
Published: December 2024

the article presents the result of the analysis of interpretations of key terms in domestic and foreign scientific literature, on the basis of which the theoretical basis of ensuring economic security of the tourism and recreation sector is supplemented. The concept of economic security of the tourism and recreation sector is formulated and its main essential characteristics are substantiated
HEAT LOSS FROM GEOTHERMAL ENERGY SOURCES
Authors: Bekirov Eskender , Voskresenskaya Svetlana , Nusretova S.
Published: December 2024

The article conducts an analysis of geothermal energy sources in Crimea for various depths of the occurrence. At a depth of up to 1000 m, the temperature is relatively not large from 34 to 650C, and at a depth of 4000 m they reach 175 – 1800C in some areas. Formulas are also given for calculating the number of Reynolds and the Nussels number used in determining heat loss from geothermal water to the pipe wall, the temperature of which in turn depends on the temperature of the surrounding soil. It is calculated to reduce the temperature in the pipeline when extracting heated water for various cases, and it was revealed that with the length of the pipeline up to 100 m, it is less than a degree. The greater the water consumption, the less the temperature decreases, and the dependence is nonlinear.
Subject: Geothermal sources of Crimea energy. The study is aimed at solving the problem associated with the extraction of low-temperature water for the supply of it to the consumer.
Materials and methods. Both analytical and calculated methods based on the use of heat transfer processes were used.
Results. It was established that with a stabilized process of extracting geothermal water from the well of the Novoselovskaya site in Crimea, a decrease in temperature for the pipeline section is relatively small, which allows it to be used for the needs of consumer heat supply.
Conclusions. Geothermal springs in Crimea are practically not used, despite the significant potential. The costs of seven sites of geothermal springs with Crimea range in the range from 600 to 4900 m3/day, while, depending on the depth of temperature, either for heat supply to consumers, or for electricity generation. On the example of the Novoselovskaya site with self-gols from 700 to 3500 m3/day, a possible decrease in temperature in the pipeline was revealed. At the same time, the temperature of the water was taken 500C, and the temperature decrease was less than 0.13% per 100 m of the pipeline.
THE CONTRIBUTION OF SIX CONTEMPORARY PHILOSOPHERS IN BUDDHIST PHILOSOPHY
Authors: Sivasai Chintala Venkata
Published: December 2024

There were two different religious and cultural traditions in ancient India. The Munis and Sramanas have a pre-Aryan past that includes wandering ascetics, yogis, and an association with water sacredness. They had the doctrine of samsara, which holds that there is essentially something unsatisfactory with the world and that the only way to find true happiness is to renounce it. Their doctrines also included Karma (action), an eternal soul, and Mukti (release). In addition to the Brahmanic philosophy, there were up to sixty-two other schools of philosophy in ancient India, all of which were antagonistic to it. The six non-Buddhist thinkers who were revered by kings, nobles, and the wise are mentioned frequently in Buddhist and secular origins. As the founders of schools of thought, they were widely recognized across the nation. A few of them were senior Buddha contemporaries, and the masses of disciples also followed them. The names of these six philosophers and their philosophies are listed below.
GATHBANDHAN: A CULTURAL ANALYSIS OF THE RITUALS AND THE PRACTICES OF MARRIAGE SYMBOLIZING SUSTAINABILITY
Authors: Davis Antony , Mukherjee Panchali
Published: December 2024

This study focuses on the vital intersection of environmental and cultural sustainability within event tourism, specifically emphasising marriage events. As the demand for unique and memorable wedding experiences continue to rise, this chapter delves into how event planners and participants can contribute to environmental preservation and cultural enrichment. By examining the strategies and practices that promote sustainability in marriage rituals and events, this study offers insights into creating meaningful celebrations that leave a positive legacy for both the environment and cultural heritage. The chapter “Gathbandhan: A Cultural Analysis of the Rituals and the Practices of Marriage Symbolizing Sustainability” critically analyses the various sustainable rituals and practices related to marriage using the cultural theory. The academic study is interdisciplinary as it focuses on different areas such as culture, economy, society, environment etcetera. The study focuses on representation as a key feature of cultural theory. The marriage rituals and practices are represented as icons, symbols, and indices embedded in various cultures which are also markers of sustainability. Some practices provide an alternative to technological hegemony in modern times. The study depicts the marriage rituals or practices as signs embedded in a network of signs where the signifier is the ritual or practice studied and the signified is the idea of multifaceted sustainability. The academic study views marriages with their varied rituals and practices as cultural texts with a politics of reception. The various rituals and practices of marriages depict consumption, a chief tenet of cultural theory as a route to sustainable economic growth. The study attempts to rehabilitate the traditional marriage rituals and practices that have been marginalized in modern times by focusing on them and proving them to be markers of sustainability.
THE EXPANDING MODEL OF THE CONFORMALLY FLAT NON-STATIC SPHERICALLY SYMMETRIC PERFECT FLUID DISTRIBUTIONS
Authors: Borkar Dr. Manjusha Hajare
Published: December 2024

The explicit expressions for pressure, density expansion, rotation, sheer and non vanishing component of flow vector have been obtained. In this this note ,we have discussed the various geometrical and physical properties of spherically symmetric metric space time obtained by Roy and Bali [5] by considering the triples of orthogonal unit vectorsα_i, β_i. Here we connect all the physical quantities obtained by Roy and Bali [5] with mathematical quantities ρ^a in Borkar and Hajare [3]. Further it is noticed that the model is expanding, rotating, shearing but non geodetic.
SHAPING THE FUTURE OF ANIMATION: A DESIGNER’S DIVE INTO 3D MODELING, EXPRESSIVE CHARACTERS, AND VISUAL STORYTELLING (2021-2024)
Authors: Meena Pramendra Kumar , Soni Pooja
Published: December 2024

The field of animation has undergone significant changes from 2021 to 2024, driven by advancements in 3D modeling and character animation technologies. This paper delves into these developments, highlighting real-time rendering, AI-driven modeling, and deep learning algorithms that have improved visual storytelling. Real-time rendering has transformed workflows, enabling the creation of dynamic, photorealistic environments while shortening production times. At the same time, AI has streamlined complex tasks like rigging and motion capture, making high-quality animation more accessible to smaller studios and independent creators. Additionally, deep learning techniques have progressed in modeling facial expressions, adding emotional depth to characters. This study looks at how these innovations are being integrated across various sectors, including entertainment, education, and healthcare, demonstrating their impact on engagement and storytelling. It also addresses the challenges designers face, such as finding a balance between artistic expression and technological complexity. By reviewing recent research and practical case studies, this paper provides a thorough overview of the changing animation landscape and anticipates future trends.
Productivity of Phenolic, Flavonoid, and Antioxidant in Justicia gendarussa Burm. f. by Different Shade and Dose of Nitrogen Fertilizer
Authors: Maulana Faizal , Batubara Irmanida , Nurcholis Waras
Published: December 2024

Justicia gendarussa Burm.f., known as gendarussa, has been used as a traditional medicine to treat thrush, headaches, bronchitis, arthritis, jaundice, otalgia, indigestion, fever, cancer, male contraception, and UV protection. J. gendarussa can grow wild as a shrub, especially in forest areas and river embankments, which can make the production of secondary metabolites inconsistent, especially phenolics group, and change the biological activity. Therefore, the purpose of this study is to determine the optimal combination of shade and nitrogen fertilizer dose for maximizing phenolic, flavonoid, and antioxidant productivity in the aerial parts of J. gendarussa. This study employed a split-plot design, with shade (0, 25, and 50%) serving as the main plot and nitrogen fertilizer doses (0, 90, 180, and 270 kg ha-1) serving as subplots. The highest productivities of phenolics, flavonoids, antioxidants, and dry weight were observed in the treatment with a nitrogen fertilizer dose of 270 kg ha-1 and no shading treatment. The dry weight of the plant's harvested aerial parts was 10.9 g plant-1. The productivity of phenolics was 210 mg GAE plant-1, while the productivity of flavonoids was 112 mg QE plant-1. Using DPPH, ABTS, FRAP, and CUPRAC methods, antioxidant productivity was determined to be 63.5; 334; 171; and 525 mol TE plant-1, respectively. Pearson correlation indicates that phenolic and flavonoid productivity is highly correlated with antioxidant productivity. Considering the research parameters of shading and nitrogen fertilizer dosage, 270 kg ha-1 nitrogen fertilizer application without shading was the optimum cultivation practice combination.
Ray-Floret Based Rapid Propagation and Detection of Somatic Variation in Selected Mutant Chrysanthemum Individuals
Authors: Kantoglu Kadriye Yaprak , Kunter Burak , Şenel Ümran , Haspolat Gulden
Published: December 2024

Chrysanthemum (Dendranthema × grandiflora Tzvelev) is an attractive plant species that responds well to mutation breeding research conducted worldwide. The isolation and propagation of mutant individuals are very important for detecting mutations in in vitro cultures. Using in vitro cultures, it is easy to isolate solid mutants. In this study, the homogeneous reproductive capacity of selected mutant individuals after irradiation was examined using ray floret cultures at the M1V1 stage, based on various flower colors and architectures. The explant materials were obtained from selected mutant plants with yellow, dark red, orange, and spoon-shaped ray florets cultivated in full bloom. After the determination of an effective sterilization method, the ray florets were cultured in Murashige and Skoog's (MS) media, which contained 0.5 mg L-1 1-Naphthalaneacetic acid (NAA) and 2.0 mg L-1 6-Benzylaminopurine (BAP). The average rate of plantlet regeneration varied depending on the genotype; mutants with yellow-colored flowers generated 0.6 plantlets per explant, those with orange-colored flowers (1.11), those with dark red-colored flowers (1.16), and those with spoon-shaped flowers (2.71). After plant regeneration, plantlets were cultured in a hormone-free MS nutrient medium to ensure full-rooted plant development. The findings of this study showed that in vitro ray floret culture could be used to swiftly and successfully carry out vegetative reproduction of pot-type Brandevil mutants, which are more susceptible to in vivo cutting propagation than pot-type Chrysanthemum cultivars. In the propagating material, there were obtained four differently colored somaclonal plants, eleven partial somaclonal plants with incurved-type ray florets, eight somaclonal plants with spatulate-type florets, one somaclonal plant with semi-double-type flower heads, two somaclonal plants with pointed and reflexing ray florets.