bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECT OF VIRGIN COCONUT OIL ON MYCOBACTERIUM SMEGMATIS AND STAPHYLOCOCCUS AUREUS TREATED WITH EXTRACTS OF ZANTHOXYLUM ACANTHOPODIUM FRUIT
Authors: JULISTIONO HEDDY , SUSENO INTAN PERMATASARI , HANDAYANI NURUL , HANDAYANI RINI , DEWI LOTULUNG PUSPA
Published: September 2021

Objectives: To understand the potency of herbal formulation of virgin coconut oil (VCO) and andaliman (Zanthoxylum acanthopodium) fruit activity against microbes, effects of ethylene acetate and hexane extracts of fruit of andaliman on viability and ions leakages of Mycobacterium smegmatis dan Staphylococcus aureus treated with VCO has been investigated.
Methods: Antibacterial activity of extracts of andaliman fruit, or VCO, or andaliman and VCO against M. smegmatis and S. aureus was investigated using MTT assay method. Membrane disruption of bacterial cells treated with the plant extract and VCO was determined by measuring potassium and sodium ions leakages using Atomic Adsorbtion Spectrophotometer.
Results: VCO of 512 μg/ml did not have antibacterial activity. In M. smegmatis treated with andaliman hexane extract, presence VCO decreased both ions leakage whereas in S. aureus treated with ethyl acetate extract only sodium ion was decreased. In both microorganisms, VCO could not protect cells of both M. smegmatis and S. aureus from death caused by andaliman extracts.
Conclusions: VCO prevented ions leakages of the bacteria treated with extract of andaliman but did not protects cells from death.
FORMULATION AND EVALUATION OF MELOXICAM MICROSPHERES FOR COLON TARGETED DRUG DELIVERY
Authors: DHAS SHRADHA KISHOR , DESHMUKH GANESH
Published: September 2021

Objectives: The objective of this research was to organize and evaluate colon specific microspheres of the meloxicam for the treatment of colorectal cancer.
Methods: Sodium alginate microspheres were prepared by ionotropic gelation method using different ratios of meloxicam and sodium alginate (1:1, 1:2, and 1:3). Eudragit-coating of meloxicam, sodium alginate microspheres was performed by coacervation phase separation technique.
Results: The microspheres were characterized by shape, particle size, size distribution, incorporation efficiency, in vitro drug release studies and stability studies. The outer surfaces of the core and coated microspheres, which were spherical in shape, were rough and smooth, respectively. The size of the core microspheres ranged from 20 to 52 μm, and therefore the size of the coated microspheres ranged from 107 to 178 μm. The core microspheres sustained the discharge for 10 h during a pH progression medium mimicking the condition of gastrointestinal tract. The release studies of coated microspheres were performed during a similar dissolution medium as mentioned above. In acidic medium the discharge rate was much slower, however the drug was released quickly at pH 7.4 and their release was sustained up to 24 h.
Conclusions: It’s concluded from this investigation that Eudragit-coated sodium alginate microspheres are promising controlled release carriers for colon-targeted delivery of meloxicam.
IMPROVEMENT OF ALOPECIA AND DECREASES IN HAIR CORTISOL AND DIHYDROTESTOSTERONE CONCENTRATIONS AFTER THE TOPICAL USE OF PLANT EXTRACTS IN MEN WITH ANDROGENETIC ALOPECIA
Authors: DO SANG-HWAN , AHN RYUN-SUP , NA MYUNG-SUK , JU HYUNG-RUEL
Published: September 2021

Objectives: Plant extracts possessing specific constituents with anti-inflammatory, antimicrobial, antioxidant, or 5α-reductase inhibitory properties are known to provide benefits against androgenetic alopecia (AGA) in men. A solid shampoo was formulated, and it contained a mixture of six different plant extracts that possess these beneficial properties against AGA. The improvement in AGA and changes in steroid concentrations were assessed after 4 months of formulated shampoo use.
Methods: This study was conducted based on a randomized, placebo-controlled, and single-blind design. Hair-related variables and hair and saliva samples were collected bi-monthly in the treatment (n=48) and placebo (n=52) groups and at a single time point in the hairy controls (n=50).
Results: The formulated shampoo was more effective on AGA than the placebo based on the hair shaft thickness and hair density in the receding hairline. The baseline hair cortisol and dihydrotestosterone (DHT) concentrations were significantly higher in the treatment and placebo groups than in the hairy controls. After 4 months, the hair steroid concentrations in the treatment group were reduced to those observed in the hairy controls, although the main effect of time on hair steroid concentrations was negligible in the placebo group. Salivary cortisol and DHT levels during the post-awakening period were comparable among the groups or assessment time points.
Conclusion: The constituents of plant extracts included in the formulated shampoo would prevent hair loss, increase hair growth effects, and reduce hair cortisol and DHT concentrations without changes in the post-awakening salivary steroid levels in men with AGA.
INTERACTION OF 3-HYDROXY PYRIDINE AND SURFACTANT MICELLES: A FLUORESCENCE STUDIES
Authors: MAHLAWAT ANSHU , GOYAL ARUN
Published: September 2021

Objective: Micellar solubilization is a powerful alternative for dissolving hydrophobic compound in aqueous environment. 3-hydroxy pyridine (3- HP) derivatives are the potential endogenous photosensitizers. 3-HP derivatives show protective effect in clinical extreme condition such as hypoxia, hyperthermia, hypokinesia. Micellization of 3-HP followed by solubilization would catalyze its pharmaceutical activities which may serve better results in medicinal and analytical fields.
Methods: Fluorescence and absorption spectroscopy techniques are used to monitor the micellar solubilization studies of 3-HP. Solubilization studies of 3-HP with various anionic, cationic and nonionic surfactants have been performed in aqueous medium around 23–25°C temperature. The solubilization action of the surfactant has also been determined by theoretical calculated spectral parameters such as empirical fluorescence coefficient, quantum yield, stokes, shift and molar absorption coefficient.
Results: 3-HP shows fluorescence excitation peak at 315 nm and emission peak at 390 nm respectively while the absorbance of 3-HP has been found to be maximum at 305 nm. The fluorescence as well as the theoretically calculated spectral data has been used to characterize the hetero environment of the micelles in terms of their polarity, probe solubilization site and critical micelle concentration.
Conclusion: This article briefly discusses the importance of surfactants in biological system model as well as the use of micelles in pharmacy as an important tool that finds numerous applications.
ANTI-INFLAMMATORY EFFECTS OF AN AQUEOUS EXTRACT OF JUSTICIA FLAVA (FORSK) VAHL (ACANTHACEAE) IN RATS
Authors: WENCESLAS KOUAME DJÈ KOUAMÉ , FRÉDÉRIC N’DIA KOUADIO , LÉANDRE KOUAKOU KOUAKOU , PAUL YAPO ANGOUÉ
Published: September 2021

Objective: Justicia flava is a plant commonly used in traditional medicine for the treatment of frictions, convulsions, body aches, pains, and fever. The aim of this study was to determine the anti-inflammatory properties of an aqueous extract of J. flava (AEJf) in rats.
Methods: Thus, 36 rats were divided into six groups of six rats each for each test. Acute anti-inflammatory activity was evaluated by induction of plantar edema following injections of egg albumin, carrageenan, or histamine. AEJf and aspirin (100 mg/kg bw) were orally administered to rats with doses ranged from 62.5 to 500 mg/kg bw before (preventive study) and after (curative study) the induction of edema. The rat’s paw edema was measured using a digital caliper thereafter. For a sub-chronic anti-inflammatory activity, sterilized cotton pellets (20±0.5 mg) were implanted in the anterior dorsal region for granuloma formation. Animals received the different doses of AEJf (62.5–500 mg/kg bw) for 7 days and on the 8th day, cotton pellets were removed and weighed, dried, and weighed again.
Results: The results of the oral administration of AEJf at doses of 62.5, 125, 250, and 500 mg/kg bw to rats showed similar acute anti-inflammatory properties such as aspirin (100 mg/kg bw) on carrageenan (1%), fresh egg albumin, and histamine injection-induced rats’ paw edema. AEJf caused 77.63% (preventive study) and 28.1% (curative study) inhibitions of carrageenan (1%) solution-induced paw edema and 61% (preventive study) and 29.62% (curative study) inhibitions of fresh egg albumin-induced paw edema. AEJf also inhibited histamine-induced edema (1 mg/mL) by 83.67% compared to the control group. AEJf significantly reduced the weight of granuloma tissue elicited by the insertion of sterile cotton pellets from 34.53 to 46.98% for wet cottons and from 45.73 to 59.45% for dry cottons.
Conclusion: AEJf possessed anti-inflammatory activity on acute and sub-chronic inflammations in rats.
A RANDOMIZED CONTROL STUDY TO EVALUATE THE ROLE OF HERBAL IMMUNOMODULATORS IN BOOSTING THE IMMUNITY AND OVERALL HEALTH OF HEALTHCARE WORKERS IN COVID-19 WARDS: AN EXPLORATORY, FEEDBACK CLINICAL STUDY
Authors: CR JAYANTHI , HR AVINASH , SRIDHAR SWETHA , K AKHILA , SRIDHAR SRIYA , KUMAWAT RAJESH
Published: September 2021

Objective: The objective of the study was to evaluate the role of the herbal immunomodulators Immusante and Guduchi in boosting the immunity and overall health of healthcare workers assigned to coronavirus disease 2019 (COVID-19) wards.
Methods: An open-label, randomized, prospective, and single center clinical study was conducted among 100 healthcare workers assigned to COVID-19 wards. Eligible subjects (50 in each arm) were randomly assigned to either arm I (Immusante+Guduchi tablets) or arm II (treatment as per the institutional policy). Assessments after 30 days of treatment included respiratory symptoms, Adapted Immune Status Questionnaire (ISQ), improvement in quality of life (Short form 12 [SF-12] Health Survey), and safety and tolerability.
Results: All 100 subjects completed the study as per the protocol. There were no respiratory symptoms in the subjects in arm 1. However, four subjects (8%) in arm II reported cough during the study period. A better Immune status improvement was seen through the adapted ISQ in arm I as compared to arm II. In each of the 8 SF-12 Health Survey domains, a statistically significant difference was observed in arm I compared to arm II. A retrospective assessment of COVID-19 infection showed only 8% of subjects as COVID-19 positive in arm I compared with 26% of subjects in arm II.
Conclusion: Considering the positive trend observed in this study in terms of ISQ, SF-12, and COVID-19 infection rates, the combination of Immusante and Guduchi in healthcare workers at a high risk of contracting COVID-19 infection had a beneficial effect in boosting immunity and overall health.
EVALUATION OF ANALGESIC (IN VIVO) ACTIVITY OF ARIFLEX TABLET IN COMPARISON WITH DICLOFENAC AND ACECLOFENAC USING ACETIC ACID INDUCED WRITHING MODEL IN MICE
Authors: NIPANIKAR SANJAY , SS CHITLANGE
Published: September 2021

Objective: The present study was conducted to evaluate analgesic activity of Ariflex Tablet which is a polyherbal formulation conceptualized and developed by Ari Healthcare Private in comparison to Aceclofenac and Diclofenac Tablet. Methods: Albino mice of either sex weighing 20–25 g were taken and divided into four groups with six animals in each group. Group 1 (Controlled Group) animals were starved overnight. Group 2 animals were orally administered with Diclofenac Tablet as Standard drug. Group 3 animals were orally administered with Aceclofenac Tablet as Standard drug and Group 4 Animals were orally administered with Ariflex Tablet. The test and standard drugs were orally administered with feeding needle after 1 h of injecting 1% acetic acid intraperitoneally in volume of 0.1 ml/10 g body weight. Writhing episodes were recorded for 30 min by counting the stretching. Results: All the tested formulations possess analgesic activity in acetic acid induced writhing model. Aceclofenac possesses strong analgesic activity compared to other formulations tested. In Ariflex Tablet Group, the number of writhes was 120.6±41.4. If compared to control group, the number of writhes was significantly less suggesting analgesic activity of Ariflex Tablet. Analgesic activity of Ariflex Tablet was close to that of Diclofenac Sodium. Conclusion: It can be concluded that Ariflex Tablet possesses significant analgesic activity. Ariflex Tablet can be used in the management of Osteoarthritis, Rheumatoid arthritis, Gouty arthritis, Lumbago, Sciatica, and Spondylitis.
La publicación periódica científica en el núcleo: bases para el desarrollo de modelos
Authors: Valdez Garza Dalia
Published: September 2021

Este artículo contiene fundamentos para elaborar modelos de estudio centrados en la publicación periódica científica, con perspectiva histórica e interdisciplinaria, desde la visión integral de la historia del libro. Las aportaciones actuales subordinan el sistema editorial al científico, ambos engranados al “sistema documental y de información”, y desarticulados de un “sistema hemerográfico” global. Se contextualiza la publicación en la ciencia, sus actores y las fronteras de sus actividades en un sistema y en otro, pero siempre en interacción y dependencia. Esta visión integral permite superar limitaciones que daban primacía a los “textos científicos” y a sus autores. El ecosistema de la publicación periódica científica se propone como base para el desarrollo de modelos de estudio en los sistemas propuestos, extensiones donde se explica su dinámica interna particular, y quiénes y cómo intervienen. Esta exploración teórico-metodológica surgió al desarrollar un “modelo de edición” para investigar el Boletín de Ciencias Médicas (México, 1910-1916).
La riqueza documental histórica y literaria del Fondo “Vanegas Arroyo y Posada” (Biblioteca Rafael Montejano y Aguiñaga de El Colegio de San Luis)
Authors: López Torres Nora Danira
Published: September 2021

El Fondo “Vanegas Arroyo y Posada” de la Biblioteca Rafael Montejano y Aguiñaga, de El Colegio de San Luis, fue creado en 2017 al recibir en donación un conjunto de impresos publicados por el editor Antonio Vanegas Arroyo durante el periodo de entre siglos en México (XIX-XX). El propósito de este artículo es presentar el Fondo y detallar las circunstancias de su creación, el origen de los documentos y sus contenidos generales, así como el proceso seguido para su preservación y difusión. Se destaca también el alcance que ha tenido, al propiciar el desarrollo de nuevas investigaciones y en el surgimiento de grupos de trabajo especializados en el estudio de estos materiales.
Propuesta de una tipología de los manuscritos novohispanos en lenguas indígenas de la Biblioteca Nacional de México
Authors: Rosas Xelhuantzi Tesiu
Published: September 2021

A partir de la revisión catalográfica y el estudio material de los documentos, este artículo delinea los ejes temáticos presentes en el corpus de manuscritos novohispanos en lenguas indígenas conservados en la Biblioteca Nacional de México. Derivada de un análisis comparativo, se propone una clasificación tipológica que considera cuatro divisiones denominadas géneros documentales. La conclusión a la que llega el planteamiento es que el abordaje de la colección como objeto de estudio permite rutas de investigación complementarias a los análisis individuales de los manuscritos.
Crímenes ilustrados: folletín e imaginario visual en la prensa rioplatense, 1846-1880
Authors: Pas Hernán
Published: September 2021

Desde su instalación a mediados de la década de 1840 en Buenos Aires, el folletín se integró perentorio a la prensa rioplatense. Tal integración no resultó pasiva, antes bien generó una serie de fenómenos notables en el precario y emergente mercado del impreso. Por una parte, reconocía y negociaba un horizonte poco o insuficientemente atendido hasta entonces: la cultura del entertainment; por otra, la progresiva “folletinización” de la prensa alcanzó su mayor despliegue con la propagación de imágenes impresas. En efecto, la alianza entre folletín e ilustración generó un tipo de lectura “masiva” que resultó una verdadera novedad en la República de las Letras. Este trabajo procura abordar la historia de esas relaciones, desde el ingreso del género en Buenos Aires (1846) hasta su estilizada culminación con los primeros folletines criollos de Eduardo Gutiérrez publicados en La Patria Argentina (1879-1880).
“La prensa como fuente para estudiar la historia y literatura en Iberoamérica". Nuevos acercamientos al estudio de la prensa en el mundo hispánico: historia, literatura y prensa”
Authors: Romero Valle Ana María
Published: September 2021

Reseña de:Nuevos acercamientos al estudio de la prensa en el mundo hispánico: historia, literatura y prensa. María Luisa Pérez Bernardo e Íñigo Fernández Fernández, coords. México: Editorial Notas Universitarias, 2018, 316 pp. ISBN: 978-607-9799-18-2.
“Nueva España: autores, impresores, ejemplares conservados y bibliotecas que los resguardan”. La imprenta en México en el siglo XVI
Authors: Cortés Ortiz Cecilia A.
Published: September 2021

Reseña de:La imprenta en México en el siglo XVI.Guadalupe Rodríguez Domínguez. Mérida, España: Editora Regional de Extremadura, 2018, 538 pp. ISBN: 978-84-9852-564-9.
El periodismo cultural español en México durante la Revolución: Ricardo de Alcázar y la revista Rojo y Gualda, 1916-1917
Authors: Gil Lázaro Alicia
Published: September 2021

Este texto analiza la primera etapa del semanario cultural Rojo y Gualda, fundado por Ricardo de Alcázar, Florisel, conocido periodista y escritor español radicado en Ciudad de México. Una larga tradición de periodismo español en este país le antecedía, y su aparición en marzo de 1916 rompió con el carácter beligerante e intervencionista mostrado por la prensa hecha por españoles en los primeros tiempos revolucionarios. Tras varios años de silencio, fue el primer intento exitoso de poner en marcha una nueva empresa periodística en el seno de la colonia española en México, de manera que –sin renunciar a los temas y modos caros al grupo al que iba dirigido– debió incluir ciertas reformas para sobrevivir en el hostil clima revolucionario y publicarse durante cuatro años y medio, hasta septiembre de 1920. Este artículo traza un perfil biográfico de Florisel, su editor los primeros 16 meses, y describe el contexto periodístico en el que apareció la revista, así como sus etapas, formato, secciones y géneros, los colaboradores y temas principales.
Comparative study on Design of flexible pavement by various methods (GI method & CBR method)
Authors: Agrawal Vivek Kumar
Published: September 2021

Abstract: In the project report, an attempt is made to design a road, based on the principles of pavement design and cost analysis of y two methods (Group Indexed and CBR Method). On the existing alignment of the road, soil samples are collected for the determination of soil characteristics like consistency limits, sieve analysis, C.B.R. values etc. Based on this the thickness of the pavement (flexible) is designed. The alignment of the road is also designed and fixed by surveying and leveling. The total road length being 497 meters of which, one section is 247m, other is 200m and the third section is 50m. The site selected for this study is of village road near Korba, Korba district of Chhattisgarh, India. Keywords: GI Method, Flexible Pavement, CBR Method, Liquid Limit Test, Plastic Limit, Standard Proctor test, OMS & MDD.
A Diasporic Study of the Tamil Movie - Nala Damayanthi
Authors: Ramesh Akshya
Published: September 2021

bstract: ‘Nala Damayanthi’ is a Tamil movie, directed by Moulee which was released in the year 2003, starring R. Madhavan, Geetu Mohandas, Anu Hassan, Sriman, Moulee and many others. This movie projects the life and problems of an Indian immigrant who goes to Australia and almost loses everything including his own identity. The movie also represents and reflects some of the issues that an average immigrant would face in a foreign land. Alienation, racial discrimination, loss and lack of identity are some of the prominent issues that are addressed in the movie. Ramji, the protagonist faces quite a lot of differences in Australia yet, he tries hard to fit in and accommodate that culture. But, in spite of all his attempts to change his behaviour and manners, he ultimately remains as an Indian and therefore, he is eventually rejected. Thus, this movie handles diasporic issues of an Indian in Australia. Keywords: Alienation, Diaspora, Racial Discrimination, Lack of Identity, Indian Immigrant
Importance of Informal Spaces in Urban Neighbourhood: A Study in Navi Mumbai, Chandigarh and Ahmedabad, India
Authors: Acharjya Ar. Bagmita
Published: September 2021

Abstract: Informal spaces in different development zones in Navi Mumbai, Chandigarh and Ahmedabad were studied to answer the question of what comprises the necessary factors for the successful use of public space. Cities exist with exceedingly fragmented zones with multiple sections of spaces. There are various categories like open or closed, with one of them being informal type which greatly impacts their social surroundings. Comprehending this will entail reviewing the importance of informal spaces in the urban fabric and how the community is impacted by them. Various design factors will also be taken into consideration on their impact on the proper functioning of an informal space. Using the qualitative analysis in six informal spaces, this article will identify patterns in informal spaces in the three cities through direct observation, participant observation and interviews. The imageability will suggest benefiting the socio-cultural aspect of a community through informal spaces and the design approach adopted to achieve this. Keywords: Informal space; open space; social impact; user approach in urban space; informal green space.
Literature Review on Interaction Analysis of Building Resting on Sloping Ground
Authors: Dulganti Dheeraj Reddy
Published: September 2021

Abstract: An increase in economic growth, as well as urbanization in the hilly areas, encourages the construction in the hilly region. Considering this fact the engineers should assure the safety of constructions in the slopy region. To understand the past attempts carried out on the constructions of the building on the slopy ground the systematic literature survey is done which includes the parameters like types of the building suitable for hilly regions, slope inclinations for safe superstructure in seismic events, types of safety measures recommended to assure the safety of superstructure and necessity of interaction analysis for the constructions in the hilly region. The survey so carried out in the paper gives a fair idea about the research gap and thus motivates researchers to carry out future research on the gap identified. Keywords: soil-structure interaction; slopy ground; bracing system; literature survey; equivalent static analysis; hilly region constructions.
Regeneration Potential of Stem Cell in the Treatment of IVD
Authors: Bhanushali Riya
Published: September 2021

Abstract: Degenerative disc disease is a prevalent musculoskeletal disorder in which damaged spinal discs cause pain upon aging, accidental injuries. Spinal discs connect adjacent vertebrae and help in maintaining mobility, flexibility and rotation of spinal cord. Spinal discs also act as shock absorbers. Intervertebral disc (IVD) degeneration is often associated with low back and neck pain, which accounts for disability worldwide. Physical therapy, spinal fusion surgeries reduce severity and symptoms of degenerative disc disease but they are not complete cure for this disease. Current preclinical studies show that mesenchymal stem cells have the capacity to repair degenerative disks by differentiation to chondrocyte-like cells, which produce proteoglycans and type II collagen. Mesenchymal stem cells (MSCs) isolated from bone marrow (BM-MSCs), adipose tissue (AD-MSCs) and umbilical cord (UC-MSCs) show potential use in cartilage and intervertebral disc (IVD) repair. Regenerative medicine and stem cell therapy hold great promise for treatment of intervertebral disc (IVD) disease. This review discusses about progression of degenerative disc disease, various types of stem cells, potential use of mesenchymal stem cells (MSCs) and embryonic stem cells (ESCs) for the treatment of degenerative disc disease. This review also focuses upon challenges encountered by the application of stem cell therapy for treating degenerative disc disease as well as future perspectives. Keywords: IVD, Stem cell therapy, AF & NP cells, MSCs, Scaffolds, Cell therapy
Dinâmica regional da indústria de transformação no Brasil (2000-2017)
Authors: Ribeiro Cássio Garcia , Cardozo Soraia Aparecida , Martins Humberto
Published: September 2021

Este trabalho tem como objetivo analisar a dinâmica regional da indústria de transformação no Brasil no período recente, por meio de um exame conjunto das alterações na estrutura produtiva e nas características desse setor nas cinco macrorregiões do Brasil (Norte, Nordeste, Centro-Oeste, Sudeste e Sul). Considerando o debate recente sobre a temática, são examinadas as mudanças ocorridas no que se refere à importância econômica e no perfil tecnológico da indústria de transformação em cada região. Os resultados indicam que dois fenômenos merecem destaque: i) o recuo da participação da indústria de transformação nas estruturas produtivas das regiões do país; ii) a continuidade da desconcentração regional da indústria de transformação, mas esse processo é lento e não modifica o perfil da divisão inter-regional do trabalho, marcada pelo predomínio do Sudeste nas atividades mais intensivas em Ciência, Tecnologia e Inovação (CT&I). Busca-se avaliar o significado desses processos para o desenvolvimento econômico do Brasil.
EXPLORING FIRST YEAR UNIVERSITY STUDENTS’ STATISTICAL LITERACY: A CASE ON DESCRIBING AND VISUALIZING DATA
Authors: Setiawan Ezra Putranda , Sukoco Heru
Published: September 2021

Statistical literacy, which is the ability to use statistics in daily life, is an essential skill for facing society 5.0. This study aims to explore first-year university students’ ability to properly use simple descriptive statistics and data visualization. Qualitative data were collected using a set of questions from 39 undergraduate students. Many students were able to calculate various descriptive statistics, but some of them were still unable to determine suitable statistics to describe the data clearly. Related to data visualization, many students failed to provide a meaningful chart that effectively shows the difference between two groups of data. Students with higher statistical literacy tend to use comparison or variability reasoning to determine the usage of descriptive statistics, and use data-based reason in visualizing the data. Improvement in statistical teaching – both in the university and the secondary school – is needed so that the students can use descriptive statistics and data visualization correctly.
Artemisia gmelinii Web. ex Stechm. within the Buryatian flora: phytocenotic confinedness, composition of essential oil
Authors: Zhigzhitzhapova Svetlana V. , Kholboeva Svetlana A. , Dylenova Elena P.
Published: September 2021

Buryatia as a part of Baikalian Siberia is one of the main centers of origin and morphological diversity of wormwood in Eurasia. There are 48 species and subspecies of wormwood within Buryatian flora, one of which is Artemisia gmelinii Web. ex Stechm. For the first time the composition of the essential oils of A. gmelinii growing in the rare community of Siberian apricot ( Armeniaca sibirica (L.) Lam) is presented in this work. Essential oils were obtained from the raw materials collected during the field works on the territory of the Republic of Buryatia (Kyakhtinsky district, surroundings of Tamir village - Southern slopes of the Tamir range) in 2020. The vegetation of the Tamir ranges slope is represented by shrub communities from the relict of Eastern Asia growing since the Miocene-Pliocene time - Armeniaca sibirica . The dominant components of essential oils of A. gmelinii from apricot community are 1,8-cineole, germacrene D, camphor, borneol, caryophyllene. Essential oils of A. gmelinii growing within the Siberian flora of one chemotype with a predominance of mono-terpenoids in the group composition form two subtypes, prevailing: 1) in the East Siberian populations of A. gmelinii with a predominance of sesquiterpenoids in the composition of essential oils; 2) in the West Siberian populations of A. gmelinii with a predominance of monoterpenoids in essential oils.
Biotesting of cultivation zoocompost of Hermetia illucens larvae
Authors: Goncharova Elena N. , Kurzenev Ivan R. , Vasilenko Marina I. , Pendyurin Evgeniy A.
Published: September 2021

A by-product of protein production from the larvae of the black soldier fly ( Hermetia illucens ) is a zoocompost consisting of a variety of organic compounds. The purpose of the work was to determine the hazard class of the zoo complex - the waste of cultivation of Hermetia illucens larvae using biotesting methods, since the use of calculated methods to determine the hazard class is difficult. Biotesting experiments were carried out on test organisms: planktonic crustacean Daphnia magna , algae Chlorella vulgaris , seeds of Avena sativa , Triticum vulgare and Hordeum sativum . It has been established that the zoocompost refers to low-risk waste. Extractions of the zoocompost stimulate the growth of plants Avena sativa and Hordeum sativum , it is supposed to be used as a phytostimulator. It has been shown that an environmentally friendly wasteless method for the production of protein additive from insects is possible.
Change of phytotoxicity of soils contaminated with oil products in the process of their microbiological remediation during the application of humic preparations
Authors: Cherdakova Alina S. , Galchenko Svetlana V.
Published: September 2021

The article presents the results of experimental studies on the assessment of the phytotoxicity of soils contaminated with oil products of various fractions (gasoline, diesel fuel, fuel oil) in the process of their microbiological remediation with the introduction of humic preparations. The studies were carried out under the conditions of a vegetation experiment, in which the processes of bioremediation of soils contaminated with various oil products were simulated using microbiodestructors and humic preparations (Ekorost and Gumi). It has been established that the implementation of bioremediation measures using microbio-destructors does not allow for complete detoxification of soil contaminated with various oil products. The manifestation of detoxifying properties of humic preparations in relation to oil-hydrocarbon pollution of soils during their bioremediation was revealed. The severity of these properties varies and depends on the type of oil-polluting product, its concentration, as well as on the properties of the preparations themselves.
Assessment of the open-mining prevalence on the territory of Moscow region
Authors: Naumova Ksenia O. , Stanis Elena V.
Published: September 2021

Lands disturbed by open cuts and associated dumps often become unsuitable for further use as construction sites. Disturbed lands are technogenically altered soils with new changed physicomechanical and physicochemical properties. The paper examines the results of researching the disturbed lands of common mineral resources open cuts in Moscow region, provides a description of the causes and types of land disturbance, as well as examples of images of disturbed lands on satellite images. For this purposes, thematic and topographic maps and remote sensing materials - satellite images of the territory of the Moscow region were used. The problems of impact of common mineral resources extraction on the natural complexes in the region, the scale of technogenic transformation of the earth surface as a result of open cuts mining as well as the geoecological problems arising in this case are considered. Numerical geoecological assessment of sand quarries in Moscow region is also given.
Assessment of radon-222 radiation activity in the design of residential buildings
Authors: Sauts Artur V. , Sauts Valery N.
Published: September 2021

In this paper, we have developed a method that allows us to evaluate the radiation activity of radon-222 based on mathematical modeling in the design of residential buildings in accordance with the rules for designing anti-radon protection. The method is based on the numerical solution of the diffusion, heat transfer, and Navier - Stokes equations, supplemented by appropriate turbulence models, initial and boundary conditions, in particular, the process of natural decay and sedimentation of radon-222 in the room is taken into account. Verification of the method for residential premises of an apartment building located on the territory of Saint Petersburg was performed. Using the proposed calculation method allows you to identify the most radiation dangerous places in the room, rationally organize the air exchange and configuration of the room, prevent the development of sick building syndrome, etc.
Ecological consciousness of the XXI century human and the ways of its verbalization in the media discourse environment
Authors: Guslyakova Alla V. , Guslyakova Nina I. , Valeeva Nailya G.
Published: September 2021

The paper aims at studying and analyzing the language implementation of the development of peoples ecological consciousness in the present-day Russian and English-speaking media discourse environment. The modern media discourse has become an important source of various environmental lexical units which can affect peoples consciousness and change their behavior in a more eco-friendly way. The research is based on two parallel and opposite scientific approaches integrated in the media discourse which are ecologisation and anthropocentrism. The study is built on the analysis of the language models of ecological issues in different popular national and international media editions of Russia and English-speaking countries; in TV documentaries; on YouTube channels; in eco-friendly bloggers speeches and texts. The findings of the research showed that the media discourse environment is actively inculcating green ideas into peoples consciousness today both in Russia and abroad. More people are trying to follow the conscious consumption lifestyle. The media language is also becoming an important tool in introducing new environmental lexical units - neologisms - which are easily disseminated in the media discourse space and are actively being adopted by society. Overall, this research has confirmed the idea that the present-day language of the media discourse space is a powerful mediator of a new life sustainable development philosophy which helps human consciousness evolve in an eco-friendly way and try to make our planet a safer, healthier and more comfortable place for living.
Modernization of the gas emissions treatment scheme of sodium bisulfite production line from sulfur dioxide
Authors: Nikolaeva Larisa A. , Khusnutdinova Elvira M.
Published: September 2021

Chemical industry enterprises are the main environmental pollutants that cause environmental problems. This is due to the production technology and the toxicity of some substances. In this paper, it is proposed to purify the gas emissions at the JSC Karpov Chemical Plant formed during the production of sodium bisulfite from sulfur dioxide by the adsorption method. As a sorption material, a modified energy waste - carbonate sludge from the chemical water treatment plant of the Naberezhnye Chelny CHPP - was used. The technological characteristics of the granular sorption material are presented. A batch adsorber with a fixed layer of granular sorption material is calculated. The modernization of the technological scheme for cleaning gas emissions from sulfur dioxide of the production line of sodium bisulfite at JSC Chemical Plant named after L.Ya. Karpov is proposed. The calculation of the prevented environmental damage and the economic effect of the modernization of the technological scheme is made.
The impact of magnesium on psycho-emotional stress and functional activity of the cardiovascular system in students from African countries
Authors: Kirichuk Anatoly A. , Klimenko Anna S. , Lobanova Yulia N. , Pobilat Anna E. , Mazilina Aksana N. , Koroleva Anastasia A.
Published: September 2021

The objective of the study is investigation of the impact of magnesium on psycho-emotional stress and functional activity of the cardiovascular system in foreign male students of African origin. A total of 33 male first course students were involved in the study. The examinees were supplemented with 150 mg/day of magnesium. Evaluation of serum and urinary Mg levels was performed using inductively-coupled plasma mass-spectrometry, whereas functional activity of the cardiovascular system and psycho-emotional stress were assessed using Angioscan-01 diagnostic complex both before and after a course of magnesium supplementation. It has been demonstrated that magnesium supplementation resulted in a significant 3% increase in serum Mg levels as compared to baseline. The observed increase in circulating magnesium levels was associated with a significant 26% decrease in stress index, whereas arterial stiffness index significantly reduced by 3%. A significant increase in absolute systole duration and time from the start of the pulse wave to a maximum of the early systolic wave was also observed. The results of the study demonstrate a significant decrease in stress index and arterial stiffness in response to magnesium intake, being in agreement with the existing data on protective effects of magnesium. Therefore, monitoring of magnesium supply and its improvement may be considered as a valuable tool supporting somatic and psychic health of students thus improving their academic performance.
O processo como espaço de diálogo pela via do princípio processual da colaboração
Authors: Jardon Guimarães de Faria Gabriela
Published: September 2021

Este artigo explora o princípio/modelo processual da colaboração, sob o ângulo das novas possibilidades de diálogo entre os sujeitos processuais que cria, as quais, depois de implementadas, tendem a adensar o coeficiente democrático interno do processo judicial. Esse diálogo entre sujeitos processuais deve ser agenciado o mais profundamente possível, forjando inclusive um dever de escuta pessoal das partes pelo julgador ou julgadora, independentemente de seu valor probatório. Tem por método a revisão bibliográfica, constatando que o princípio/modelo da colaboração contém em si exigências éticas impostas a todos os atores processuais, com base no reconhecimento de que, acima dos interesses das partes, há o interesse público de que o processo se encaminhe à solução mais justa alcançável, dever este de que juízes e partes devem ser guardiões.
Treatment and prognosis of pleuropulmonary blastoma: A Single-Center Report of 31 Cases
Authors: Wang Feng , Zhuang Lin , Liang Jianghua , Li Le , Wang Hui , Tang Jue , Zeng Jia , Liu Wei
Published: September 2021

Objectives: Pleuropulmonary blastoma (PPB) is a very rare,
characteristic and highly aggressive neoplasm occurring in children,
most under 6 years of age. We assessed the clinical characteristics,
treatment modalities, treatment outcomes, and prognostic factors
affecting survival in patients with PPB treated at our institution over
a 10-year period to improve the prognosis of PPB. Methods: From November
2008 to November 2019, 31 children (21 boys and 10 girls) with a median
age of 30 months (range, 22 days-54 months) were treated at our
institution. Here, we describe the patient characteristics, treatment
modalities and treatment outcomes. The Kaplan-Meier method was used to
estimate the progression free survival probability (PFS) and overall
survival (OS). Log-rank test was performed for comparison between
groups. Results: 3 children were lost to follow-up and 2 were dead of
postoperative complications. Of the 26 patients included in the
follow-up, 16 PPB patients displayed tumor-free survival. The 6-month,
1-, 3-, and 5-year PFS were 80.8%, 69.0%, 60.4% and 60.4%,
respectively. Accordingly, the 6-month, 1-, 3-, and 5-year OS were
84.6%, 72.7%, 60.1% and 60.1%, respectively. Sex, extent of surgery
and chemotherapy/irradiation appeared to affect the survival, while age
and pathology type appeared not to do. Conclusions: PPB is an aggressive
neoplasm. To improve the prognosis of PPB, we should promote radical
resection and improve the auxiliary treatment measures.
Analyzing The Use of The Year Four, Theme Three Student Book of the 2013 Curriculum to Build Environmental Awareness
Authors: Handayani Mentari Deka , Rahmawati Laili Etika , Prastiwi Yeny , Supriyanto Eko , Widyasari Choiriyah
Published: September 2021

The 2013 Curriculum emphasizes the cultivation of individual values. There are 18 values to be instilled, one of which is caring for the environment. These values are taught through daily teaching and learning activities. Environmental awareness is discussed in the year four student book under theme three. This research is designed as a descriptive-qualitative study facilitating document study. Data collection was done using the data analysis technique, content analysis. The validity of the data was tested using semantic validity and stability reliability. Results showed that the value of environmental awareness was present in theme three of the year four student book and can be divided into three indicators. These indicators include caring for plants, caring for animals as well as caring for other human beings. In conclusion, theme three of the year four student book is regarded as appropriate teaching material.
Interactive Pictorial Story as Learning Media for Third Grade Students
Authors: Inayah Nurul , Cahyaningtyas Andarini Permata , Kusumadewi Rida Fironika
Published: September 2021

This study aims to develop an interactive pictorial story as a learning media on theme 2 Loving Plants and Animals and to determine its feasibility, practicality, and effectiveness. This study uses the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation). In this study, the results obtained include: (1) The feasibility of the media obtained from the validation results by 5 validators obtained an average of 0.83 for content quality indicators and objectives, instructional quality indicators obtained an average of 0.84 and technical quality indicators obtained an average of 0.83. The average number of all indicators is 0.83 with the category "very valid". (2) The practicality of the media obtained a percentage of 98% in the "very feasible" category of teacher responses and 96% in the "very feasible" category of student responses. (3) The effectiveness is calculated by using the gain test of 0.56 indicating an increase in student learning outcomes in the "medium" category. The result of this research can be a reference to understand that an interactive pictorial story will be a big help for teachers in conducting an interesting teaching and learning process, especially during this pandemic. The pictorial story was created in an interactive format, so students can learn the material in a fun and interesting way. Besides, in this outbreak, students need to have a technology-based learning resource other than their school books so they can study independently.
Analysis of Fifth Graders’ Higher Order Thinking Skills in Studying Human and Animal Respiratory Organs
Authors: Maryani Ika , Hanifah Rifky , Purwanti Siwi , Onate Rafael
Published: September 2021

Background: Higher order thinking skills (HOTS) are crucial for students to face the 21st century development. This study aimed to determine higher order thinking skills of the fifth graders at Muhammadiyah elementary school in Demangan and Baitussalam II Islamic elementary school in solving questions on human and animal respiratory organs.Method: A descriptive quantitative approach was employed. It included survey and ex-post factor designs. The research data were collected using tests.Result: The participants of the study achieved medium scores on three categories of HOTS. Thirty nine percent of Ibnu Thufail fifth graders achieved a medium score on judgement and critical thinking, 48% of Ibnu Rusdy fifth graders obtained a medium score on similar category, and 42% of the Muhammadiyah fifth graders got low scores on judgement and critical thinking. Meanwhile in problem-solving, 43% students were in medium category, 39% in low category, and 32% in medium category. Forty eight percent of the students obtained medium scores and 52% achieved poor scores.Implications: The research findings imply that students’ HOTS in natural science need to be improved. Novelty: The present study revealed students’ HOTS based on judgment and critical thinking, problem solving, logic and reasoning skills.
Herpes Zoster Anterior Uveitis with Hyphaema
Authors: Arvinth Rajagopal , Zahari Mimiwati , Reddy Sagili Chandrasekhara
Published: September 2021

Herpes zoster ophthalmicus usually manifests in elderly people as a unilateral painful skin rash in a dermatomal distribution of the ophthalmic division of the trigeminal nerve shared by the eye and ocular adnexa. It is the reactivation of varicella-zoster infection. Most common ocular manifestations of this disease include keratitis, conjunctivitis, and anterior uveitis. Severe hyphemia as a complication following herpes zoster uveitis is uncommon. We report a rare case of a 90-year-old lady with herpes zoster ophthalmicus and diabetes mellitus with unusually severe hyphemia. The disease responded well to systemic and topical steroids with improved vision outcome. Early referral to an ophthalmologist, detailed evaluation, and immediate treatment are mandatory to prevent permanent vision loss in these patients.
optimisation ofEnergy Accumulation for Renewable Energy sources
Authors: Milan Belik
Published: September 2021

This project focuses on optimisation of energy accumulation for various types of distributed renewable energy sources. The main goal is to prepare charging - discharging strategy depending on actual power consumption and prediction of consumption and production of utilised renewable energy sources for future period. The simulation is based on real long term data measured on photovoltaic system, wind power station and meteo station between 2004 - 2021 . The data from meteo station serve as the input for the simulation and prediction ofthe future production while the data from Pv system and wind turbine are used either as actual production or as a verification of the predicted values. various parameters are used for trimming of the optimisation process. Influence of the charging strategy discharging strategy, values and shape of the demand from the grid and prices is described on typical examples of the simulations. The main gal is to prepare and verify the system in real conditions with real load chart and real consumption defined by the model building with integrated renewable energy sources. The system can be later used in general installations on commercial or residential buildings