bluuebunny/crossref_metadata_2025 huggingface dataset:
Selective embolization of thyroid arteries as an alternative treatment of amiodarone-induced hyperthyroidism
Authors: Brodowska-Kania Dorota , Narloch Jerzy , Piasecki Piotr , Saracyn Marek , Kamiński Grzegorz
Published: October 2022

Background:
A selective embolization of thyroid arteries (SETA) is a rarely performed procedure. Although 35 years have passed since the first description of the SETA application, only about 150-200 procedures have been published so far.
Case presentation:
We present the case of a patient successfully treated for amiodarone-induced hyperthyroidism using the SETA method. Patient had a history of paroxysmal atrial fibrillation (PAF), diagnosed three years earlier, treated with an anticoagulant - rivaroxaban. During 35 months, amiodarone was used as a method for treating the PAF. During the treatment, the patient developed hyperthyroidism. The patient was treated with thiamazole, propranolol and sodium perchlorate. After obtaining euthyreosis, SETA was performed. The patient underwent selective embolization of the left superior and right inferior thyroid arteries with a sclerosing agent – polyvinyl alcohol with good clinical effect. A thyrosthetics agents were discontinued.
Conclusions:
This case demonstrates difficulties in differential diagnosis of the type of amiodarone-induced hyperthyroidism. Normal ultrasound image of the thyroid gland and absence of antithyroid antibodies suggests type II of amiodarone-induced hyperthyroidism. While, a good, fast response to thyrostatics – type I. It seems, therefore that, the diagnosis of the mixed type of amiodarone-induced hyperthyroidism is justified. Further research are also required to assess the safety and efficacy of SETA in amiodarone-induced hyperthyroidism in larger groups of patients.
Activity of spa resorts in Busko-Zdrój and Solec-Zdrój in 1939-1945
Authors: Trzeskowska-Kubasik Karolina
Published: October 2022

Funkcjonowanie uzdrowisk w Busku-Zdroju oraz w Solcu-Zdroju w czasie okupacji niemieckiej jest tematyką pomijaną do tej pory w historiograﬁi polskiej. Na temat ich działalności można znaleźć jedynie enigmatyczne wzmianki. Głównej przyczyny tego stanu rzeczy można upatrywać w ubogim stanie źródeł – mowa tutaj zwłaszcza o materiałach dotyczących Solca-Zdroju. Przedmiotem niniejszego artykułu jest m.in. omówienie działalności uzdrowisk w latach 1939-1945 a także skali zniszczeń, jakie poniosły w wyniku działań okupanta niemieckiego. Uzdrowiska w Busku-Zdroju oraz w Solcu-Zdroju poniosły duże straty w czasie okupacji niemieckiej. Zakłady lecznictwa uzdrowiskowego zmieniły swoje przeznaczenie, i stały się przede wszystkim miejscami rekonwalescencji dla Niemców. Warto zauważyć, że ludności polskiej niemal całkowicie ograniczono do nich dostęp. Część zakładów zdrojowych uległa zniszczeniu, a ich wyposażenie zrabowano. W wyniku okupacji niemieckiej zdewastowano także bazę noclegową w Busku-Zdroju i Solcu-Zdroju. Tylko w Busku-Zdroju liczba pokoi dla kuracjuszy zmniejszyła się o 350. Podczas gdy w Busku-Zdroju kuracjuszy przyjmowano już w 1945 roku, Solec-Zdrój został otwarty jako całoroczne
uzdrowisko w 1961 roku.
A novel heterozygous mutation in the hydroxymethylbilane synthase gene in a case with acute intermittent porphyria
Authors: Ghosh Ritwik , León-Ruiz Moisés , Singh Sardar Sona , Naga Dinobandhu , Roy Dipayan , Ghosh Tapas , Dubey Souvik , Benito-León Julián
Published: October 2022

Porphyrias are rare metabolic disorders caused by inherited or acquired enzymatic defects in the heme biosynthetic pathway. They are grouped into acute hepatic porphyrias and photocutaneous porphyrias. Acute intermittent porphyria, the most prevalent subtype of acute hepatic porphyrias, is caused by a mutation in the hydroxymethylbilane synthase gene. In this work, a case of a 13 year-old Indian female presenting with multi-organ involvement (Neurological: episodic seizures, behavioral abnormalities, acute onset progressive flaccid-motor quadriparesis, multiple cranial nerve palsies, respiratory paralysis, dysautonomia, and posterior reversible encephalopathy syndrome; Gastrointestinal: recurrent attacks of abdominal pain, nausea/vomiting, isolated transaminitis, and acute pancreatitis; and Renal: metabolic alkalosis and refractory dyselectrolytemia) which resulted in significant diagnostic dilemmas. She was eventually diagnosed as a case of acute intermittent porphyria harboring a novel hydroxymethylbilane synthase gene mutation (p.Arg173Trp).
Meninism and Preconceived Ideology with specific Indian Dimension of Human Rights in Today’s Changing Globalized Scenario: A Critical Appraisal
Authors: Dr. Ramesh Kumar  , Rohit Kumar Verma
Published: October 2022

Men and Women both are an integral part of nature and integrant with each and another for wholeness to ensure the existence and survival of this human life in contrary time also for revitalization and revival in this mortal world. When time is changed then human conduct also changes consequently some women are abusing the law against men resultantly human rights of men are being violated very seriously in the gravest manner which is the contravention of life, personal liberty and security of men. The deprivation and endanger of life, personal liberty and security of men is in very plight conditions under exceptions in India. To prevent the abuses of law, preconceived ideology, predefined consequences against men in the protection of human rights to secure ends of justice for men is now need of hour and necessity. This research paper deals with human rights of men in today’s changing scenario. It has specially been emphasized on the preconceived ideology of people against men on this basis the discrimination and decision are taken prejudicially. Some laws also are in existence due to this preconceived ideology which is not justified in today’s changing globalized world under rule of law and democratic society, subjecting to exceptions. This preconceived ideology and its predefined consequences against men are inconsistent with and in derogation of human rights, abridging and taking away the rights of men. It reveals the Quantum of doctrine of protective discrimination for women against men, bearing in mind the principle of reasonable classification. When any person says or justifies that the particular thing is right or wrong, the same is stated on the basis of foundation root or quantum of knowledge of that person thereby the person has the understanding and sensibility accordingly and consequently, the person acts. But this research article does not include misogyny. It is not against the feminism. The history gives the evidences about the untold sorrow of women for the contravention of their human rights. This research article also is in favour of women empowerment and women human rights but no innocent men be sentenced. Everyone has inherent human rights by birth including human rights of men. Human rights for men are also available as per laws in today’s changing globalized world.
Preparation of 5-Selenocyanatouracil by a more convenient method and evaluation of some pharmacological properties
Authors: Noori Sahar Muayad , Neamah Nadheerah F. , Al-Jadaan Shaker A. N.
Published: October 2022

A convenient method for preparation of 5-Selenocyanatouracil (5-SeU), this compound gains importance because it is similar to 5-Fluorouracil which is one of the famous uracil derivatives as an anticancer drug. Some of invitro pharmacological activities such as DPPH antioxidant effects and antimicrobial activity, in addition to median lethal dose (LD50) were estimated. The study aimed to use a convenient synthesis procedure, and evaluation of in vitro pharmacological activity, also to determine the median lethal dose of 5-SeU. 5-SeU synthesis was carried out in very good yield through a direct reaction between 5-Iodouracil and freshly prepared potassium selenocyanate in refluxing aqueous solution to give light-gray crystalline. Antimicrobial measured by disc diffusion method. LD50was determine using Albino rats. 5-SeU compound was branded by FT-IR; 13C- NMR and 1H- NMR spectroscopic data. The results showed no antibacterial effects for most of test bacteria with a low inhibition effect on Staph. Aureus, and Pseudomonas aeruginosa, with moderate inhibition zone at candida culture.
Impacto económico del gasto de los estudiantes universitarios en el desarrollo local. Un estudio de caso en la comuna de Puerto Montt, Chile
Authors: Soza Sergio , Vásquez Johanne , Llanquilef Francisco
Published: October 2022

Se evaluó el impacto del consumo de los estudiantes universitarios en la comuna de Puerto Montt, Chile, mediante encuestas y la matriz input-output. La información considerada en el estudio se basa en los años 2018 y 2019. Los resultados revelaron que el gasto de consumo de los estudiantes es relevante y equivalente al gasto de los turistas nacionales y contribuye al desarrollo local. Además, se concluye que el impacto del consumo (por medio de sus efectos inmediato, directo, indirecto e indirecto hacia el resto del sistema económico), se ve favorecido por los efectos multiplicadores de las actividades relacionadas con el consumo tanto de los estudiantes como de los turistas.
Risk Identification and Analysis in Software Development in Bangladesh IT Industry: A Hybrid Model
Authors: Rahman Tania , Saha Shanto Kumar , Sohel Md. Sajjadur Rahman , Maula Md. Tamim , Bowmik Abhijit , Nabil Rashidul Hasan
Published: October 2022

Software risk management is a critical and multi-stage process. All over the world, IT Industries face some threats during software risk management processes. Bangladesh is not exceptional. Our principal goal is to manage risk for Bangladesh's IT Industry. To gain a clear and transparent idea survey is the most effective way. And so, we arranged a survey questionnaire and collected data for risk impact areas on Bangladesh IT Industry. A workable and feasible risk management approach prompts an idea for the risk-mitigating plan. In any case, the high proportion of IT project failures demonstrates the futility of risk mitigation activities. From the survey, it is discovered that the most irritating obstructions behind software disappointment for the presence of covered-up and inconspicuous risks and lack of user communication, and lack of proper training on new technology which is overlooked in the greater part of the models. The proposed model works with the improvement of the risk mitigation plan through four phases, the DVC committee, and the NUT train-up team. Depending upon the survey replies added another unique feature called the NUT train-up team. The model considered all four phases of risk management, with the mitigation phase and training on new technologies receiving the greatest attention.
Research on the Influence of Digital Economy on Rural Governance
Authors: Xia Nan , Xie Jingwen , Yuan Yucheng , Cao Qifan , Li Deyu
Published: October 2022

Based on the panel data of various provinces and cities in China, this paper uses the entropy method to measure the development index of digital economy and rural governance in China during 2016-2020, and then empirically analyzes the driving effect of digital economy on rural governance. The research results show that the indicator development of the digital economy plays a fundamental role in the operation of some mechanisms of rural governance, and is further promoting the transformation of rural governance structure through positive external effects.
Battery management system of UAV Based on IOT
Authors: Zhang Xu , Zhang Xi
Published: October 2022

Lithium ion battery is a new type of high-energy battery developed successfully in the 20th century. Because of its high energy, high battery voltage, wide operating temperature range, long storage life and other advantages, it has been widely used in military and civil micro unmanned aerial vehicles. In order to monitor the charge and discharge and flight of UAV in real time, this paper designs a UAV battery management system based on the Internet of things, which transmits the battery data to the Internet of things platform in real time through the wireless transmission module. After testing, this design can achieve the effect of real-time monitoring of UAV battery pack.
Antimicrobial Effects of Selenium and Chitosan Nanoparticles on Raw Milk and Kareish Cheese
Authors: Mohamed Shimaa N. , Mohamed Hamdy A. , Elbarbary Hend A. , Abo EL-Roos Nahla
Published: October 2022

The contamination of milk and its dairy products with different microorganisms could cause public health hazards. Antibacterial nanoparticles (NPs) are a novel way to ensure that milk and milk products are safe. The present study investigated the effect of chitosan NPs (CS-NPs) and selenium NPs (Se-NPs) on some microorganisms, which consequently affect raw milk and Kareish cheese. Small-sized nanomaterials of Se-NPs and CS-NPs at the size of approximately 20 nm were used in this study. The samples were 700 ml raw milk and 700g Kareish cheese manufactured from 3000 mg milk. The concentrations of used nanoparticles were 0.5%, 1%, and 1.5% for Se-NPs and 2.5%, 5%, and 10% for CS-NPs. They were used to improve the microbial properties of milk and Kareish cheese samples during storage at the refrigerated temperature of 4°C. The aerobic plate count, Enterobacteriaceae count, Staphylococcus count, and mold count were significantly reduced in milk and Kareish cheese samples treated with CS-NPs and Se-NPs. The study has confirmed that CS-NPs and Se-NPs indicated high antimicrobial activity against the studied microorganisms at all concentrations although CS-NPs were more effective than Se-NPs. It can be concluded that these NPs can be used as preservatives in milk and milk products, such as Kareish cheese. In addition, increasing the concentrations of these NPs by 10% for CS-NPS and 1.5% for Se-NPS boosted their effects.
PENGARUH STRES KERJA TERHADAP PRESTASI KERJA KARYAWAN PADA HOTEL PLAZA KUBRA KENDARI
Authors: Djauhar Asri , Baso Nasir Andi , Subhan Subhan
Published: October 2022

This study aims to determine the effect of work stress on employee performance at the Hotel Plaza Kubra Kendari. To achieve this goal, qualitative and quantitative data are used, data collection techniques by observation, interviewes and literature study are used.The population in this study were all employees of the Hotel Plaza Kubra Kendari, totaling 25 people. Sampling using non-probability sampling technique or census method. The data collection instrument used a questionnaire with a likert scale, each of which had been tested and had met the validity and reliability requirements. Data analysis using simple linear regression and using hypothesis testing, namely partial t test and determination R test.Based on the results of simple linear regression analysis, it shows that there is a positive and significant effect between work stress on employee performance at the Hotel Plaza Kubra Kendari with a tcount 6,205 > ttable 2,069 with a significance value of 0,00 < 0,05. So that the proposed hypothesis can be accepted. Based on this, it shows that work stress has a positive and significant effect on employee work performance at the Hotel Plaza Kubra Kendari.
PKM Agribisnis Bunga Di Tpu Punggolaka Kelurahan Punggolaka Kecamatan Puwatu Kota Kendari Provinsi Sulawesi Tenggara
Authors: Abdul Manan La Ode , Puguh I Wayan , Bariun L.M.
Published: October 2022

Program Ipteks yang melibatkan kelompok tani budidaya tanaman bunga dan kelompok usaha bunga bertujuan untuk meningkatkan kapasitas petani bunga dan kelompok usaha bunga dengan target agar produktivitas dan keragaman tanaman bunga petani meningkat dan meningkatkan kapasitas pengelolaan usaha bunga bagi kelompok usaha bunga. Disamping itu diharapkan meningkatkan pendapatan dan kesejehteraan petani bunga dan kelompok usaha bunga. Program Ipteks ini dilaksanakan di TPU Punggolaka Kota Kendari. Operasional program Ipteks meliputi rekruitmen anggota kelompok mitra, penyuluhan dan pelatihan serta pembuatan demplot teknik budidaya tanaman bunga-bungaan, pembuatan bokashi, teknik penyimpanan bunga dan teknik merangkai bunga serta papan ucapan yang baik serta manajemen pengelolaan kelompok. Setelah berakhir kegiatan program Ipteks ini diharapkan produksi bunga meningkat, terdapat diversifikasi produk bunga serta agribisnis tanaman bunga di TPU Punggolaka Kota Kendari dan sekitarnya dapat berkembang dan berkelanjutan sehingga pendapatan dan kesejahteraan masyarakat meningkat.
Exploring the Global Issues in English Language Teaching: EFL Teachers’ Perspective
Authors: A. Ahmed Sami Hussein
Published: October 2022

The purpose of this research is to examine how a particular textbook series portrays global issues. It explored teachers' attitudes towards the inclusion of global issues in the textbooks using content analysis and interviews with six English language teachers. The study found that the textbooks are primarily focused on subjects that promote and develop competence and that global issues are not given priority. The teachers who were interviewed identified a list of factors that could affect the selection of global issues to be incorporated in the textbooks.
Premalignant Conditions of Bone
Authors: Eckhoff Michael D. , Wells Matthew E. , Padilla Osvaldo , Polfer Elizabeth M. , Castagno Christopher J. , Thabet Ahmed M. , Elzamly Shaimaa , Wilson Harry L. , Rajani Rajiv
Published: October 2022

Development of malignancy is a multifactorial process, and there are multitude of conditions of bone that may predispose patients to malignancy. Etiologies of malignancy include benign osseous conditions, genetic predisposition, and extrinsic conditions. New-onset pain or growth in a previously stable lesion is that should concern for malignant change and should prompt a diagnostic workup for malignancy.
Manajemen Pendidikan Kewirausahaan Bagi Peserta Didik Paket C pada Pusat Kegiatan Belajar Masyarakat di Kabupaten Karawang
Authors: Yunengsih Neng , Rostini Deti , Tejawiani Ida
Published: October 2022

Penelitian ini membahas terkait manajemen pendidikan kewirausahaan peserta didik Paket C pada Pusat Kegiatan Belajar Masyarakat (PKBM) berdasar aspek-aspek perencanaan, pengorganisasian, pelaksanaan, pengawasan, kendala, dan solusi mengatasi kendala pada pendidikan kewirausahaan bagi peserta didik paket C. Metode yang digunakan pada penelitian ini adalah analisis deskriptif kualitatif, sedangkan teknik pengumpulan data dilakukan melalui wawancara, dan observasi. Dari hasil penelitian diperoleh kesimpulan bahwa perencanaan pembelajaran dengan menyiapkan pendidik dan sosialisasi pada PKBM. Pengorganisasian pada pembelajaran disesuaikan dengan skill dan kemampuan kompetensi yang dimiliki, baik yang bersertifikat secara resmi maupun yang sifatnya skill otodidak. Pelaksanaan pembelajaran yakni menyiapkan ruang komputer dan media pendukung pembelajaran pendidikan kewirausahaan serta menyediakan berbagai sumber belajar diantaranya modul online. Pengawasan pembelajaran dilakukan secara rutin yang dilakukan oleh Pengelola dan Yayasan serta melibatkan tutor setiap tahunnya. Kendala pembelajaran yakni pengaturan alokasi waktu pembelajaran, penyesuaian metode pembelajaran pandemic dengan pembelajaran jarak jauh, dan dalam proses pembelajaran warga belajar yang sudah bekerja minat belajarnya kurang, karena lelah bekerja. Solusi dalam mengatasi kendala pembelajaran yakni memberikan sosialisasi pembelajaran, tutor memberikan pembelajaran secara daring dengan pengerjaan tugasnya diberikan waktu yang fleksibel, dan tutor memberikan dukungan yang sifatnya membangun rasa percaya diri warga belajar dalam mengikuti proses pembelajaran.
Küçükkalay, Abdullah Mesud. Mehmet Genç: Bir Alimin Hayat ve İlim Serencamı. İstanbul: Ötüken Yayınları, 2022. 543 Sayfa. ISBN: 9786254082900.
Authors: ELİBOL Numan
Published: October 2022

A. Mesud Küçükkalay tarafından kaleme alınan Mehmet Genç: Bir Âlimin Hayat ve İsim Serencamı (Ötüken Yayınları, İstanbul 2022) adlı eser, Mehmet Genç’in hayat hikayesini ve akademik çalışmalarını konu edinmektedir. Çalışma sırasında Genç’in zorlu hayat hikâyesi, insani faziletleri, entelektüel kişiliği, bilimsel kapasitesi ve Osmanlı Tarihi ve Osmanlı İktisat Tarihi alanına yaptığı katkılar konu edilmektedir. Çalışma boyunca Genç’in kişiliği ve bilimsel-mesleki performansıyla geride kalanlara örnek olduğu ve Osmanlı Tarihi ve Osmanlı İktisat Tarihinin geri ve edilgen algısını değiştirip dinamik ve dirençli yüzünü ortaya çıkardığı gösterilmeye çalışılmıştır.
“This Disintegrating Force”: Reading Theodore Dreiser’s Sister Carrie as a Narrative of Black Upward Mobility
Authors: Potgieter Koen
Published: October 2022

In this essay, I argue that Theodore Dreiser’s 1900 novel Sister Carrie can be read as a narrative of African American migration to the Northern cities. Sister Carrie engages with social change at the turn of the century, of which the migration of African Americans and others to large urban centers was a significant part. The novel describes the social fall and ruin of the middle-class figure Hurstwood while it depicts Carrie as an ethnic Other becoming rich and famous. In numerous accounts of Carrie’s attitudes and behavior, there are striking similarities to stereotypes of African Americans, which were widely circulated through the era’s popular culture. Moreover, the way in which Carrie achieves fame as a Broadway actress echoes the success that a number of black performers were experiencing there for the first time. Through these resemblances, the turn-of-the-century reader could come to recognize an important subtext in Sister Carrie—the possibility of upward mobility for African Americans moving to places such as New York City or Chicago.
Stephenie Meyer’s Twilight Series and the ‘Post(-)ing’ of Feminism
Authors: Spieler Sophie
Published: October 2022

Immensely popular with a largely female readership, Stephenie Meyer’s Twilight series and its male hero Edward Cullen have become literary and cultural phenomena to be reckoned with. However, critical readers—especially in the blogosphere—have observed that in terms of gender and sexuality, all is not well in Forks, Washington. This essay seeks to find out if the series indeed “[s]inks [i]ts [t]eeth into [f]eminism,” as one commentator put it (Sax). In recent years, the death of feminism has been proclaimed repeatedly in academia as well as in popular culture. The reasons for the demise of the ‘f-word’ vary according to the standpoint of the obituary’s author: The feminist experiment was either successful enough to render itself obsolete or, by choosing ‘unnatural’ and subversive goals, stripped itself of its right to exist. Regardless of the particulars of feminism’s passing—was it murder, suicide, or death of old age?—critics and commentators seem to agree that we now live in a ‘postfeminist’ age. Against the backdrop of Meyer’s novels, I discuss the contested process of ‘post(-)ing’ feminism and its various theoretical and cultural implications. Focusing on the construction of masculinities and femininities, I relate the novels to issues in contemporary feminism such as alterity, agency, and domesticity.
Scanning electron microscope energy dispersive X-Ray, chemical, organoleptic, and microbiological quality of banana peel (Musa paradisiaca L.) at different fermentation durations
Authors: Utama Cahya , Sulistiyanto Bambang , Haidar Muhammad , Barus Oktavianus , Haikal Agum , Nugraha Muhammad , Sulistiono Septian , Bakhtiar Akhmad
Published: October 2022

Objective: This research aims to examine the effect of different fermentation times on the results of scanning electron microscope energy dispersive X-ray (SEM-EDX), chemical, organoleptic, and microbiological quality of banana peel.
Materials and Methods: The design in this study used a completely randomized design (four treatments and four replications). The treatments in this study were different durations of fer¬mentation of banana peels; T0 = no fermentation; T1 = 6 days; T2 = 12 days; and T3 = 18 days. The research parameters were chemical, organoleptic, microbiological quality, composition, and SEM-EDX images. Analysis of chemical, organoleptic, and microbiological quality data was done using analysis of variance, followed by Duncan’s multiple range testing at the 5% significance level, while the elemental composition and SEM-EDX images were analyzed descriptively.
Results: The results of the study showed that the length of fermentation had a significant effect (p < 0.05) on moisture content, ash, crude fiber, nitrogen-free extract, and all organoleptic quality variables of banana peels. Different fermentation durations had no effect (p > 0.05) on crude protein, ether extract, metabolic energy, total lactic acid bacteria, total bacteria, Gram positive or negative bacteria, and total fungi on banana peels. The analysis showed that the elemental composition of banana peels is C, Na2O, Cl, K2O, MgO, SO3, SiO2, and P2O5.
Conclusion: Eighteen days of fermentation improved the chemical quality, organoleptic, microbi¬ological, elemental composition, and SEM-EDX image of fermented banana peel.
Marbling score, cholesterol, and physical–chemical content of male Bali beef fed fermented pineapple peel
Authors: Bulkaini Bulkaini , Dahlanuddin Dahlanuddin , Ariana Tirta , Kisworo Djoko , Maskur Maskur , Mastur Mastur
Published: October 2022

Objective: The study was conducted to determine the marbling score, fat and meat color, choles¬terol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and physical–chemical con¬tent of male Bali beef fed fermented pineapple peel.
Materials and Methods: Twelve heads of male Bali cattle with an initial weight of 168.46 ± 11.95 kg were put into individual cages at random based on a completely randomized design with three treatments and four heads of Bali cattle as replicates, namely T0 = NG + (39% MC + 61% RB + 0% fermented pineapple peel); T1 = NG + (10% MC + 70% RB + 20% fermented pineapple peel with yeast culture); and T2 = NG + (15% MG + 65% RB + 20% pineapple peel fermented by lactic acid bacteria). The sample of Bali cattle meat used in testing the research variables was the LD muscle, with as many as 24 samples for each treatment. The data were analyzed based on the analysis of variance using the Statistical Product and Service Solutions software program, following Duncan’s test with 5% confidence.
Results: The results showed that the treatment T2 could increase the marbling quality of the meat from 2.58% to 4.00%. The cholesterol content (80 mg/100 gm), HDL (60 mg/100 gm), LDL (10 mg/100 gm), water-holding capacity (36.10%), cooking loss (29.16%), tenderness/shear force (4.08 kg/cm2), crude protein (22.99%), crude fat (4.23%), and meat collagen (1.65%) were determined.
Conclusions: Adding 20% of fermented pineapple peel by lactic acid bacteria to the ration can improve the quality of marbling, produce cholesterol, and the physical–chemical value of meat that meets the Indonesian National Standard.
Identification of lipid regulatory genes modulated by polyherbal formulation in chicken liver tissues using transcriptome analysis
Authors: Marimuthu Saravanakumar , Suresh Subramaniyam , Souza Prashanth
Published: October 2022

Objective: To elucidate the cellular mechanisms of polyherbal formulation [Kolin PlusTM (KP)], genomics was performed to delineate the genes and pathways associated with lipid regulation through transcriptional profiling of the liver in commercial broilers raised on diets deficient in choline chloride (CCL).
Materials and Methods: The gene expression patterns were studied for four groups [normal diet: normal, choline chloride deficient (CCD), KP (400 gm/ton), and CCL (400 gm/ton)] using Agilent microarray on day 42. The hierarchical cluster analysis was carried out on 12,614 differentially expressed genes (DEGs) with a similar expression.
Results: Out of 12,614 significant DEGs, 1,926, 448, and 1,330 genes were expressed at higher rates, and 413, 482, and 1,364 were expressed at lower rates than CCD (CCD vs. normal), CCL (CCL vs. CCD), and KP (KP vs. CCD), respectively. GO enrichment analysis of DEG further revealed the significant association of biological process items with the lipid, sterol, and lipoprotein metabolic processes. In particular, peroxisome proliferator-activated receptor gamma coactivator 1 alpha, carnitine palmitoyl transferase I, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme com¬plex subunit beta, and patatin-like phospholipase domain containing 2 genes involved in fatty acid oxidation and lipase C, ABCG5, ABCG8, acetyl-CoA carboxylase, ATP citrate lyase enzyme, and peroxisome proliferator-activated receptor gamma genes involved in lipogenesis were altered by KP intervention for lipid metabolism.
Conclusions: These findings reveal that the supplementation of KP prevents fatty liver-associated problems in broiler chickens by modulating the expression of the above-mentioned genes that are responsible for the oxidation of fatty acids and lipogenesis in the liver.
Molecular identification of blaTEM gene of extended-spectrum beta-lactamase-producing Escherichia coli from healthy pigs in Malang district, East Java, Indonesia
Authors: Effendi Mustofa , Hartadi Erwan , Witaningrum Adiana , Permatasari Dian , Ugbo Emmanuel
Published: October 2022

Objective: The increase and prevalence of multidrug-resistant bacteria in livestock animals are serious public health concerns. This study aimed to identify the presence of the blaTEM gene in extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli isolated from rectal swabs of apparently healthy pigs in Malang District, East Java, Indonesia.
Materials and Methods: A total of 120 rectal swab samples were collected from the pigs. The rectal swabs were screened for the presence of E. coli using standard microbiological identifi¬cation procedures. The Kirby–Bauer disk diffusion method identified multidrug-resistant E. coli. Five different classes of antibiotics were used to identify multidrug-resistant isolates, including Ciprofloxacin, Trimethoprim, Tetracycline, Streptomycin, and Aztreonam. Multidrug-resistant E. coli isolates were characterized for the presence of ESBL using double-disk synergy test methods. The presence of blaTEM genes was determined using polymerase chain reaction methods.
Results: The results of this study indicated that 107 (89.2%) out of 120 samples analyzed were positive for E. coli isolates. A total of 32 (29.9%) E. coli isolates were identified to be multidrug-re¬sistant and further subjected to molecular testing. The molecular analysis revealed (5; 15.6%) E. coli isolates to harbor the blaTEM gene.
Conclusion: The results of this study revealed that pigs and products of pork origin must be considered a source of transmission of ESBL-producing E. coli to public health important under the food chain.
TR: Stres ve Kişilik Tipleri: Bir Derleme Çalışması

EN: Stress and Personality Types: A Review
Authors: MERCAN O , KABADAYI Sema , ASLAN Sel
Published: October 2022

TR:

Yaşamımızın ayrılmaz bir parçası olan stres, özellikle zorlayıcı etkenler ile karşılaştığımızda ortaya çıkan zihinsel ve bedensel belirtileri içeren tepkiler bütünüdür. Stres başta psikolojik ve fizyolojik etkiler olmak üzere bireyleri çok yönlü bir şekilde etkilemekte; bu etkilerle birlikte bireylerin davranışlarını şekillendirmektedir. Kişilik insanın karşılaştığı zorluklara verdiği davranışsal ve bilişsel savunma mekanizmalarının dışavurumu ile oluşmaktadır. Bu nedenlerle stres ve kişilik yapısı arasında bir bağlantı vardır. Zorlayıcı stres süreçlerinde bireylerin yaşadıkları stresin kişilik tipleri ve beş faktör kişilik özellikleri ile ilişkileri, birçok araştırmada ele alınmıştır.

Bu inceleme yazısında stresle ilişkili verilen zihinsel tepkileri ve stratejileri incelemek, stres ve kişilik yapısı arasındaki ilişkileri ortaya koymak amaçlanmıştır. Bu amaçla alanda gerçekleştirilen çalışmalara yönelik bir derleme yapılmıştır. Bu kapsamda, stresin ana yapısı ve özellikleri ile kişilik tipleri ve beş faktör kişilik özellikleri arasındaki ilişkilerini inceleyen çalışmaların derlemesi yapılarak, bu alanda çalışan araştırmacıların yararlanması amaçlanmıştır.

EN:

Stress, which is an inseparable part of our lives, is a set of reactions including mental and physical symptoms that occur especially when we encounter challenging factors. Stress affects individuals in many ways, especially psychological and physiological effects. These influences shape the behavior of individuals. Personality is formed by the expression of behavioral and cognitive defense mechanisms that people give to the difficulties they face. For these reasons, there is a connection between stress and personality structure. The personality types and the five-factor personality traits of the stress experienced by individuals in challenging stress processes have been discussed in many studies.

In this review, we aimed to examine the mental responses and strategies related to stress and to reveal the relationships between stress and personality structure. For this purpose, we conducted a compilation study. In this context, we have compiled studies examining the relationship between the main structure and characteristics of stress, personality types, and five-factor personality traits and aimed to benefit researchers working in this field.
AMBULATÓRIO DE PEQUENOS PROCEDIMENTOS NA ATENÇÃO PRIMÁRIA
Authors: Andrade Ferreira Ana Paula , Paiva dos Santos Artur
Published: October 2022

Refletir sobre a proposta de implantação do Ambulatório de Pequenos Procedimentos (APP) em uma Unidade de Atenção Primária à Saúde (UAPS) de Fortaleza para treinamento em serviço de médicos em formação do Curso de Pós-Graduação Lato Sensu em Atenção Primária à Saúde. Ensaio reflexivo de caráter descritivo e teórico, dividido em duas fases metodológicas. A primeira consistiu na breve revisão da literatura sobre a temática, de modo a possibilitar uma discussão teórica sobre o objeto de reflexão. A segunda foi a descrição crítico-reflexiva de uma proposta para viabilizar a implantação de APP clínicos e cirúrgicos nas UAPS. A literatura revela diversas experiências sobre APP nas UAPS, viabilizando, em termos teóricos, a proposta de implantação e implementação desse ambulatório. A implantação de APPs clínicos e cirúrgicos para treinamento em serviço de médicos em formação contribuirá para que objetivos do referido curso sejam alcançados.
FISIOTERAPIA
Authors: Sasaki Katia , Teixeira Machado Maria Lúcia , Guerra Aquilante Aline
Published: October 2022

Este estudo teve objetivo de analisar como as Diretrizes Curriculares Nacionais estão contempladas nos Projetos Pedagógicos de Cursos (PPC) de graduação em Fisioterapia de universidades públicas do estado de São Paulo, bem como a percepção dos seus coordenadores quanto às estratégias de ensino-aprendizagem utilizadas. Trata-se de pesquisa qualitativa, interpretativa-explicativa, por meio de pesquisa documental de cinco PPC e de entrevistas semiestruturadas com coordenadores de cursos. As análises - documental dos PPC e temática de conteúdo das entrevistas - foram realizadas em dois eixos: Currículo e Perfil Profissional. Os resultados demonstraram que três currículos ainda refletiam concepções conservadoras, organizados por disciplinas fragmentadas, atividades didáticas e metodologias de ensino-aprendizagem tradicionais, não se articulando com os perfis do egresso e profissional; porém, dois PPC têm construído estratégias de reformulação curricular. Os relatos dos coordenadores contribuíram para análise que apontou necessidade de atualizações para avanço da formação profissional em Fisioterapia.
The Adaptation to Freezing Tolerance of Hydrated Lettuce Seeds: Effects of Regional Climate and of Seed Characteristics
Authors: Han Yingying , Jaganathan Ganesh K , Zhou Jingwen , Wei Shiwei , Liu Baolin
Published: October 2022

BACKGROUND:With global warming, soil seed banks at high altitudes face dual challenges, excessive water absorption and thinner snow cover that increase underground temperature. A better understanding of freezing tolerance of hydrated seeds provides insights for conservation in natural soil seed banks.OBJECTIVE:To understand the adaptation mechanisms of seed freezing tolerance under various climates, in relation to cooling rate and seed size.MATERIALS AND METHODS:Twelve ecotypes of lettuce (Lactuca sativa) seeds were collected from different geographical locations around the world. Seeds were fully hydrated and tested for their freezing tolerance using programmed cooling methods.RESULTS:The size of seeds from different climate regions varied, and was correlated with the freezing tolerance of the hydrated seeds (P<0.05). Larger seeds showed poorer freezing tolerance. The local climates of maternal plants were also well correlated to seed freezing tolerance (P<0.05), especially under slow cooling conditions. The seeds collected in regions with high spring rainfall exhibited greater freezing tolerance.CONCLUSION:Freezing tolerance of hydrated seeds is affected by the climate of maternal plants and by seed size. Our data revealed the existence of an adaptation mechanism of freezing tolerance among various ecotypes of lettuce seeds.
NÚCLEO DE EDUCAÇÃO PERMANENTE EM SAÚDE
Authors: Santos Karen Christina Rodrigues dos , Alvarenga Luiz Fernanda Calage
Published: October 2022

A Educação Permanente em Saúde é uma proposta ético-político-pedagógica que visa a transformação e a qualificação da atenção à saúde, dos processos de formação e das práticas de educação em saúde, além de incentivar a intersetorialidade. Este estudo teve como objetivo implementar o Núcleo de Educação Permanente em Saúde (NEPS) na rede de Atenção à Saúde de um município do interior do Rio Grande do Sul. Especificamente, buscou avaliar a opinião dos profissionais sobre o NEPS. Foi um relato de experiência oriundo da pesquisa realizada durante o Mestrado em Ensino na Saúde, na qual foram utilizados instrumentos como diário de campo e grupo focal para produção dos dados, que, posteriormente, foram analisados com base na análise de conteúdo de Bardin. Como categorias resultantes dessa análise, tomando por base os objetivos do estudo e o referencial teórico, destacaram-se: EPS e educação continuada: necessidade de compreensão conceitual e política; NEPS Dom Pedrito: entre limites e possibilidades, o que foi possível (des)aprender. Frequentemente, a EPS é vista como ação secundária, e nesse ponto ressalta-se a importância do NEPS, como indutor de práticas reflexivas sobre os processos de trabalho, qualificação dos serviços e minimização dos agravos e ampliando a qualidade de vida dos usuários. O NEPS proporcionou o trabalho colaborativo entre os profissionais, que conseguiram levar para seu cotidiano o que refletiram e aprenderam durante as atividades. Conhecer as condições de saúde de cada local, possibilita aos profissionais a reflexão sobre suas práticas e se esse cenário atende as necessidades da população.
Analisis Laporan Penjualan Guna Peningkatan Laba CV. Sinar Batu Alam
Authors: Permatasari Yuli Intan , Subandoro Agus
Published: October 2022

In a company, the preparation of financial statements is very important. Financial statements are considered as a tool in decision making. In addition, to compile a financial report, requires several other reports including sales. The sales report is used as one part of the content that must be presented in the financial statements. In observing business processes, business people need to know the importance of financial reports as well as daily sales reports in various business fields. The purpose of this study is to analyze the sales report, whether there is an increase or decrease in a sale using profitability ratio analysis. Increasing profits is the main goal of every company, therefore it is important to know whether a company is experiencing problems in sales or not. At the company CV. Sinar Batu Alam in 2019, 2020, and 2021 always experiences an increase in sales. Thus, the company is very effective in achieving a goal to make the company always improve and get bigger and can make products or goods more well known by the local community and abroad.
Dalam sebuah perusahaan, penyusunan laporan keuangan sangatlah penting. Laporan keuangan dianggap sebagai alat dalam pengambilan keputusan. Selain itu, untuk menyusun laporan keuangan, diperlukan beberapa laporan lain termasuk penjualan. Laporan penjualan digunakan sebagai salah satu bagian dari isi yang harus disajikan dalam laporan keuangan. Dalam mengamati proses bisnis, para pelaku bisnis perlu mengetahui pentingnya laporan keuangan serta laporan penjualan harian di berbagai bidang usaha. Tujuan dari penelitian ini adalah untuk menganalisis laporan penjualan, apakah terjadi kenaikan atau penurunan penjualan dengan menggunakan analisis rasio profitabilitas. Meningkatkan laba merupakan tujuan utama setiap perusahaan, oleh karena itu penting untuk mengetahui apakah suatu perusahaan mengalami masalah dalam penjualan atau tidak. Di perusahaan CV. Sinar Batu Alam pada tahun 2019, 2020, dan 2021 selalu mengalami peningkatan penjualan. Dengan demikian perusahaan sangat efektif dalam mencapai suatu tujuan agar perusahaan selalu berkembang dan semakin besar serta dapat membuat produk atau barang lebih dikenal oleh masyarakat lokal maupun luar negeri.
The use of mixed methods to advance positive psychology: A methodological review
Authors: Clark Rachael S. , Plano Clark Vicki L.
Published: October 2022

A call for diverse research approaches in positive psychology by the International Positive Psychology Association (2015) and the Journal of Positive Psychology(2017) challenged psychology researchers to consider methodology outside traditional quantitative methods. The purpose of this methodological review was to examine the use of mixed methods approaches in empirical studies in positive psychology. The review identified 56 positive psychology articles published between 2010 and 2019 that used a mixed methods approach. To our knowledge, this is the first review of mixed methods methodology in the field of positive psychology. The small number of published articles in that period indicate mixed methods is either not currently a widely used methodology in the field or it is being used without identifying terminology. Those studies using mixed methods often used positive psychology to inform an intervention in the quantitative strand and gathered interviews within the qualitative strand. Opportunities for growth for positive psychology researchers include interpreting data in mixed methods style and strengthening the identification of key features of the approach in the text.
BIOGRAPHICAL SKETCH OF THE COMPOSER A. MULEAR
Authors:   Academy of Music, Theater and Fine Arts, Republic of Moldova, Trocinel Daniela
Published: October 2022

The composer Alexandr Mulear was born on May 18, 1922 in the Ukrainian city of Savran, Odessa region, and died on June 17, 1994 in Chisinau, Republic of Moldova. Throughout his life he distinguished himself as a talented composer and musician, a skilled pedagogue, and last but not least as an energetic cultural activist. A. Mulear bequeathed works that manage to stand out by their uniqueness and clarity, based mainly on the Moldovan folk art, treasury and folk melodies. His composition activity can be divided into three periods: the first period of musical creativity (1949-1955), the second period (1956-1970), and the third, last period of creativity, from 1971 to the end of ofhis life.
PECULIARITIES OF THE MUSICAL LANGUAGE AND COMPOSITION IN SNEJANA PÎSLARI’S COMPOSITION FOR PIANO TREI PORTRETE MUZICALE: СHOPIN, SKRIABIN, RACHMANINOV
Authors:   Academy of Music, Theater and Fine Arts, Republic of Moldova, Cabacov Dmitri
Published: October 2022

The author of the given article analyzes the piano composition by Snejana Pâslari „Trei portrete musicale” examined in terms of its content and form. The conclusion is made that the musical language and the specifics of composition and dramaturgy of this composition are determined by its artistic idea and the composer’s individual style related to the implementation of the late romanticism stylistic paradigm.
SAFEGUARDING THE MOSAIC PANEL ART (ART ATTRIBUTES), AUTHOR MIHAI BUREA: ATTRIBUTE FOR THE VALORIZATION OF THE NATIONAL CULTURAL HERITAGE
Authors:   Academy of Music, Theater and Fine Arts, Republic of Moldova, Jabinschi Ion
Published: October 2022

The author discusses the issue of preserving and relocating / reassembling a monumental work of art, included in the list of national heritage values – the mosaic panel „Art (Attributes of Art)”, made by the artist Mihai Burea (1972) on the facade of the former Palace of Culture of Trade Unions, Rascani sector in Chisinau, dismantled in 2018, following the demolition of the block. The importance of the mosaic panel is enhanced by the status of the image, as a product of an interaction between the sender and receiver and, at the same time, as a place of transition to the mentality that generated it, as an object of representation and as an object-means of transmission/communication of a written message/implicit to the genre.
THE IMPORTANCE OF THE BASE IN SCULPTURE, ITS FORM AND ROLE
Authors:   Academy of Music, Theater and Fine Arts, Republic of Moldova, Dobrovolschi Oleg
Published: October 2022

The content of the article deals with an important element of the sculpture – the pedestal/ plinth. On it are inlaid all the main data related to the theme of the sculpture, the technique of execution, the time when it was executed and the name of the author. Pedestals can differ in shape, size and proportion. The ways of interpreting the pedestal/plinth in sculpture require knowledge of the purpose of its placement in a particular architectural or landscape environment. Some pedestals from the works of the great Romanian sculptor C. Brâncuşi are also analyzed as examples.
Productivity and Working Time Structure of Timber Forwarding in Flatland Thinned Pine Stand with the Use of Farm Tractors
Authors: Kulak Dariusz , Szewczyk Grzegorz , Stańczykiewicz Arkadiusz
Published: October 2022

Farm tractors are very popular in Poland and other European countries. When coupled with trailers equipped with a crane with a grapple, they are also used, especially in easily accessible, flat terrain, for timber forwarding in the CTL (Cut-to-Length) method. A comparative analysis of working time and productivity was performed on two forwarding units, consisting of a farm tractor Ursus and a Farma trailer with the load capacity of 6 tons, as well as a farm tractor Valtra Valmet and a Palms trailer with the capacity of 9 tons, which forwarded wood in a mature pine stand. An analysis was done for 64 work cycles with an average load volume of 2.1 m3 for the former unit, and 36 cycles with an average load volume of 7.9 m3 for the latter. The working time structure of both units was similar. During work, tractor operators spent most time, i.e. over 35%, loading the timber, then travelling with the load and unloading. The lowest share in the work cycle, around 5%, belonged to travelling without a load and forwarding. The average forwarding time for the Farma unit amounted to 33 minutes and was about twice shorter than that for the Palms unit, amounting to 64 minutes. The distance covered during loaded travel was the only factor that had a significant influence on the duration of forwarding cycles. The coefficients of correlation between these variables were 0.56–0.76. The net productivity obtained in the operating time of the Palms unit was 7.5 m3×PMH-1 and was almost twice as high as that of the Farma unit, i.e. 3.8 m3×PMH-1. For both units multiple regression models were developed, in which forwarding cycles productivity is calculated based on the volume of the transported load and the distance of loaded travel.