bluuebunny/crossref_metadata_2025 huggingface dataset:
SYNTHESIS, ANTIBACTERIAL ACTIVITY AND DOCKING STUDIES OF BENZYL ALCOHOL DERIVATIVES
Authors: SULAIMAN Mamman , HASSAN Yusuf , TASKİN TOK Tugba , NOUNDOU Xavier Siwe
Published: May 2020

Benzyl alcohol derivatives were synthesized, and characterized using NMR and FTIR spectroscopic techniques. For the first time, the antibacterial activities of the synthesized compounds were examined using disc diffusion method by measuring the diameter of the zones of inhibition against Staphylococcus aureus and Pseudomonas aeruginosa. The results demonstrated that the activity was concentration dependant, and that the compounds were generally potent against P. aeruginosa. Only two of the compounds were active against S. aureus. In terms of broad spectrum activity, compound 2d (35 mm) was found to exhibit a promising efficacy which surpassed that of the standard drug (amoxicillin).The binding of compounds 2a-e to the glucosamine-6-phosphate synthase (GlcN-6-P) active-site revealed that all the synthesized compounds fitted into the GlcN-6-P active-site receptor cavity, exhibited potential hydrogen-bonding interactions with the proximal amino acid residues and aligned similar to amoxicillin. Interestingly, it has been found that the most active compound, 2d also appeared to have a relatively low binding energy (-52.8901 kcal/mol).
Saludo del Presidente del XXII Congreso Colombiano y I Congreso Bolivariano de Obstetricia y Ginecología. Doctor Guido Parra. Saludo del Director Ejecutivo, Doctor Tomás Morales
Authors: Parra Anaya Guido
Published: May 2020

La llegada del Nuevo Milenio tiene una feliz coincidencia con la realización de nuestro Congreso Nacional de Ginecología y Obstetricia y concomitantemente el I Congreso Bolivariano de nuestra especialidad.
Calcioantagonistas en trabajo de parto pretérmino: un meta-analisis
Authors: Méndez Salamando Omar , Caicedo Cerezo Edinson , Cifuentes Rodrigo
Published: May 2020

OBJETIVO: Revisar los reportes obtenidos en la literatura sobre la eficacia de los calcioantagonistas como drogas uteroinhibidoras en trabajo de parto pretermino. MATERIALES Y METODOS: Se buscaron estudios clínicos controlados en medline, The cochrane library, internet, Se aplicaron tablas de 2 x 2, se calculó riesgo relativo e intervalo de confianza y se determinó diferencias estadísticamente significantes para tiempo de uteroinhibición y efectos adversos. RESULTADOS: No hubo diferencias estadísticamente significantes al compararlo con otros tocolíticos en cuanto al tiempo de uteroinhibición. Los calcioantagonistas tuvieron incidiencia menor de efectos adversos siendo estos estadísticamente significantes. CONCLUSION: Los calcioantagonistas son una buena alternativa como terapia uteroinhibidora en trabajo de parto pretérmino.
Endometriosis apendicular: una inusual localización de endometriosis extragenital
Authors: Arbelález Casas Felipe , Stemberg Angela María , Vásquez Trujillo Nidia Angélica
Published: May 2020

La endometriosis apendicular es un hallazgo infrecuente del compromiso extragenital de la enfermedad. Es usualmente asintomática, aunque puede generar un cuadro clínico de apendicitis. Su tratamiento, una vez realizado el diagnóstico, puede evitar complicaciones posteriores, ya sea por perforación o adherencias. La laparoscopia se constituye en una alternativa de elección para su manejo, con una mínima morbilidad para la paciente.
El fomento de rutas turístico-literarias en el Caribe: el caso de Aracataca y la “Ruta Macondo”
Authors: Rubén Pérez Luis , Martínez Lina María , Galindo Silvia Leonor
Published: May 2020

La consolidación del turismo cultural en Colombia, y en particular del turismo literario, requiere el esfuerzo integral y articulado de instituciones públicas y empresas privadas en pro del desarrollo regional y local de comunidades que cuentan con expresiones, manifestaciones y bienes del patrimonio cultural nacional. Estas comunidades, de ser organizadas y administradas acorde a estándares técnicos, se constituyen en referentes de conservación de la identidad, de integración social y proyección de prácticas e innovaciones en emprendimiento cultural. Para estudiar la experiencia en turismo literario que oferta Aracataca (Colombia) —pueblo natal y referente cultural de la obra literaria del nobel Gabriel García Márquez—, se apeló a un análisis cualitativo de carácter descriptivo en el que, a partir del contraste de fuentes documentales y del trabajo de campo por medio de observaciones y diálogos no estructurados como turistas incógnitos, fue posible reconocer las fortalezas, los riesgos y las debilidades para la consolidación de la “Ruta Macondo”, para lo cual se emplearon como epicentro los atractivos y la experiencia turística de Aracataca en el último lustro.
La geología del derecho internacional –gobernanza, democracia y legitimidad
Authors: Weiler J.H.H.
Published: May 2020

Traducción al español del texto seminal del profesor J. H. H. Weiler en el que explora la relación entre la democracia, la gobernanza y el derecho internacional a lo largo de la historia, a través del novedoso enfoque de la geología. En la interacción entre estos tres conceptos y en la pregunta por la legitimidad del derecho internacional, el profesor Weiler identifica tres etapas claves (transaccional, comunitaria y regulatoria) que permiten comprender con mayor precisión este complejo fenómeno.
Una aproximación a la sentencia judicial emitida por el Tribunal de Justicia de la Unión Europea el 6 de septiembre de 2017 en relación con la crisis migratoria europea
Authors: Hellman Jacqueline
Published: May 2020

Los flujos migratorios no constituyen un fenómeno nuevo. No obstante, en la actualidad, los datos arrojados son alarmantes. De hecho, a finales del año 2016 se alcanzó un récord en la medida en que el número de personas desplazadas ascendió a 65,6 millones. En este sentido, debe señalarse que el continente europeo se ha visto especialmente afectado por esta crisis. Teniendo en cuenta lo anterior, debemos mencionar que algunos Estados Miembros de la Unión Europea han adoptado sus propias medidas, las cuales se han alejado -en ocasiones- de las premisas impuestas por la referida organización internacional. Ante esta situación, es relevante examinar la postura que mantuvo el Tribunal de Justicia de la Unión Europea en un determinado caso que dio lugar a la esperada sentencia del 6 de septiembre de 2017.
DETERMINANTES FINANCEIROS DO ENDIVIDAMENTO DOS ESTADOS BRASILEIROS NO PERÍODO DE 2006 A 2016
Authors: Xavier Júnior Antônio Erivando , Rebouças Rômero Matheus Macêdo , Regis Salvio Delmas , Rêgo Thaiseany De Freitas
Published: May 2020

O estudo analisa os indicadores de gestão financeira e identifica qual a sua relação com o endividamento dos Estados brasileiros, no período de 2006 a 2016. Para tanto, adota a análise com dados em painel, para avaliar a relação funcional da Lei de Responsabilidade Fiscal com o endividamento dos Estados brasileiros, considerando os dados disponíveis na página eletrônica da Secretária do Tesouro Nacional. De acordo com os resultados obtidos, constata-se que existe uma relação funcional entre os indicadores de gestão financeira e o endividamento dos Estados brasileiros com a Federação, capaz de explicar 81,83% das variações ocorridas no período analisado.
ABSENTEÍSMO E CONTABILIDADE PÚBLICA: UM ESTUDO TEÓRICO
Authors: Mendes Nara Cristina Ferreira , Matias-Pereira José
Published: May 2020

O presente ensaio teórico apresenta uma discussão crítica que objetiva destacar o fenômeno do absenteísmo no ambiente organizacional.  A literatura analisada apresentou contribuições ao longo dos anos, contudo, pouco se sabe ainda sobre o custo do absenteísmo nas organizações públicas. As principais contribuições deste estudo são evidenciar o estado da arte sobre o absenteísmo, bem como as variáveis adotadas para compreender esse fenômeno; e, abordar estudos relacionados às áreas econômico-financeira e contábil. Observou-se como lacuna de pesquisa a ausência de estudos voltados aos custos do absenteísmo nas organizações públicas, fato que requer pesquisas que contribuam com sua adequada mensuração.
PLANTES MÉDICINALES DES FORMATIONS VÉGÉTALES DE LA BAIE DE RIGNY-ANTSIRANANA À MADAGASCAR
Authors: Rakotonandrasana Stéphan , Rakotondrafara Andriamalala , Rakotondrajaona Roland , Rasamison Vincent , Ratsimbason Michel
Published: May 2020

Des enquêtes ethnobotaniques ont été menées dans les formations forestières de la baie de Rigny-Antsiranana à Madagas- car. Ces formations forestières sont des zones clés de la biodiversité malgache et constituent la principale source d’appro- visionnement des populations locales en plantes utiles. Trente-huit informateurs d’âge compris entre 15 et 80 ans, tradipra- ticiens, mères et pères de famille et connaissant bien les plantes médicinales, ont été enquêtés en les amenant en forêt ou bien en leur montrant des spécimens d’herbier. La méthode d’enquête indivi- duelle retenue était l’entretien semi-struc- turé. Cinquante-trois espèces de plantes médicinales réparties dans 50  genres  et 28 familles ont été recensées. Trente-huit espèces (68,6 %) sont endémiques de Madagascar. Les dix premières espèces les plus utilisées ont des indices de fidéli- té élevés pour les maladies indiquées. Dix-neuf espèces ont des indices de fidéli- té élevés (> 60 %) pour diverses maladies. Les maladies auxquelles les informateurs rattachent le plus grand nombre de plantes médicinales sont les affections du système digestif  (maux  de  ventre  et   diarrhée), les maladies générales (les plaies et la fatigue), les infections et infestations (le paludisme), tout comme la grossesse, la naissance et la puerpéralité. Les indices de fidélité de Adansonia madagascariensis et Senna alata destinées respectivement à la lutte contre la perte de poids et l’hyperten- sion artérielle sont également élevés. Toutes ces maladies sont fréquentes à Madagascar. Les formations végétales de la baie de Rigny-Antsiranana  constituent un réservoir de plantes médicinales pour la région Nord de Madagascar. Les connais- sances locales relatives à ces plantes n’ont pas été transcrites mais restent orales et risquent d’être perdues. La végétation naturelle y est menacée par la pression anthropique et l’absence de plan de conservation. Des  recherches  chimiques et pharmacologiques sur les espèces endémiques, et des mesures de conser- vation de la végétation, sont nécessaires pour leur valorisation et leur   protection.
EVALUATION OF FLEXIBLE PAVEMENT DAMAGE DEGREE WITH PAVEMENT CONDITION INDEX METHOD (CASE STUDY: ARGOPURO ROADS - BANYUWANGI STA. 0+000 TO STA. 2+600)
Authors: Kriswardhana Willy , Koesoemawati Dewi Junita , Susanto Trio Sagita
Published: May 2020

Argopuro Roads Banyuwangi Regency with a length of 2.6 km is a switching route for heavy vehicles and buses from the north of Banyuwangi to Jember. The increase in traffic volume from year to year as well as the construction of factories and warehouses along the roads resulted in a decrease in road capability to receive loads on it. To know the type and the extent of damage occurring on Argopuro Roads is done a research which will be able to determine the appropriate type of maintenance. The determination of road condition is done by Pavement Condition Index method (PCI). Road improvement is calculated by using the component analysis method from Department of Highways Regulation No. 378/KPTS/1987. Based on the result of research, the index value of pavement condition in survei by using PCI method is 58.07. The improvement of road is done in the segment with the failure condition to the fair with the handling of the improvement in the form of recontruction. Based on the calculation result in this research, it resulted that the pavement structure has thickness of 10 cm surface course, thickness of 25 cm base course, and thickness of 63 cm sub base course.

Ruas Jalan Argopuro Kabupaten Banyuwangi dengan panjang ruas 2.6 km merupakan jalur pengalih untuk kendaraan berat dan bus dari arah utara kota Banyuwangi menuju Kota Jember. Adanya peningkatan volume lalu lintas dari tahun ke tahun serta pembangunan sejumlah pabrik dan gudang pada sepanjang ruas jalan tersebut mengakibatkan menurunnya kemampuan jalan untuk menerima beban di atasnya. Untuk mengetahui jenis dan tingkat kerusakan yang terjadi pada ruas Jalan Argopuro, dilakukan penelitian yang dapat menentukan jenis pemeliharaan yang sesuai. Penentuan kondisi jalan dilakukan dengan metode Pavement Condition Index (PCI). Perbaikan jalan dihitung dengan menggunakan metode analisa komponen dari peraturan Departemen Bina Marga Nomor 378/KPTS/1987. Berdasarkan hasil penelitian, nilai indeks kondisi pekerasan jalan yang disurvei dengan menggunakan metode PCI yaitu 58,07. Perbaikan jalan dilakukan pada segmen dengan kondisi gagal (fail) hingga sedang (fair) dengan penanganan perbaikan berupa rekonstruksi. Berdasarkan hasil perhitungan pada penelitian ini menghasilkan struktur perkerasan jalan dengan ketebalan tebal lapis permukaan 10 cm, tebal lapis pondasi atas sebesar 25 cm, dan tebal lapis pondasi bawah setebal 63 cm.
THE PLANNING OF ARTIFICIAL RECHARGED WELLS AT PURI BUNGA NIRWANA, BUKIT PERMAI, AND GUNUNG BATU HOUSINGS AT JEMBER
Authors: Wahyuni Sri , Halik Gusfan , Wulandari Wahyu Sri
Published: May 2020

Puri Bunga Nirwana, Bukit Permai, and Gunung Batu Housings are some of the housings that exist in Sumbersari subdistrict. These housings are the third former residential land that was initially able to rainwater seeped into the land of the free but is now covered by housing buildings. The effect of this case is the water cannot go into the land directly but the weather even in times of flooding rains. Therefore, to overcome this problem, it is necessary to do a study and planning of artificially recharged wells in the area. From the result of research with the basic circle and square pad at Puri Bunga Nirwana Housings for the types of houses with an area of 72 m2, 84 m2, and 105 m2 were made artificial recharged wells with a diameter of 1 m and a depth of 2 m. While at Bukit Permai and Gunung Batu Housings for the types of houses with an area of 75 m2, 90 m2, 101 m2, and 202 m2 were made artificial recharged wells with a diameter of 1 m and a depth of 2 m. And the useful cross-section used on each housing is the square cross-section.

Perumahan Puri Bunga Nirwana, Perumahan Bukit Permai dan Perumahan Gunung Batu merupakan beberapa perumahan yang ada di Kecamatan Sumbersari. Ketiga perumahan ini dahulunya merupakan lahan yang awalnya mampu meresap air hujan ke dalam tanah secara bebas akan tetapi kini tertutup oleh bangunan-bangunan perumahan. Hal ini menyebabkan air tidak dapat langsung masuk ke dalam tanah tetapi menggenang bahkan banjir di saat hujan turun. Oleh karena itu, untuk mengatasi permasalahan ini perlu dilakukan perencanaan sumur resapan di daerah tersebut. Dari hasil penelitian dengan penampang lingkaran dan penampang persegi pada Perumahan Puri Bunga Nirwana untuk tipe rumah dengan luas 72 m2, 84 m2, dan 105 m2 dibuat sumur resapan dengan diameter 1,0 m dan kedalaman 2,0 m. Pada Perumahan Bukit Permai dan Perumahan Gunung Batu untuk tipe rumah dengan luas 75 m2, 90 m2, 101 m2 dan 202 m2 dibuat sumur resapan dengan diameter 1,0 m dan kedalaman 2,0 m.dari hasil perhitungan diketahui bahwa penampang yang efektif digunakan pada masing-masing perumahan adalah penampang persegi.
STABILIZATION OF EXPANSIVE SOIL WITH MIXING CA(OH)2 (EXPANSIVE SOIL CASE STUDY: JATILUHUR HAMLET, GLAGAH AGUNG VILLAGE, PURWOHARJO DISTRICT, BANYUWANGI REGENCY)
Authors: Carisa Celia Nindy , Ma'ruf Mokhammad Farid , Putra Paksitya Purnama
Published: May 2020

Expansive soils can cause problems in construction due to changing volume changes. The area that is suspected to have an expansive soil type is Glagah Agung village, Purwoharjo District, Banyuwangi. Every season change, the construction of the building is always damaged, especially on the structure of the building. In the rainy season, the land will expand and cause the building to rise, while at the dry season the land will shrink and there is a decline in buildings. In the face of these problems, it is necessary to do special treatment to improve the nature of the expansive soil. One is chemical stabilization, adding chemicals to improve soil properties and reduce their development potential. In this study, the stabilizers used are Ca (OH) 2 lime with a percentage of 4%, 6%, 8%, 10%, 12% with curing time for one day. The results of soil become less plastic with an increase of lime content. The decrease of plasticity index is supported by grain test which is the decrease of clay fraction grain on soil mixed with lime according to the USCS method and AASHTO method. There was a decrease in the percent of original primary soil development which was initially 11.9% decreased to 2.181% 4% lime content, and 0% at 6% to 12%.

Tanah ekspansif dapat menimbulkan masalah dalam konstruksi akibat perubahan volume yang berubahubah. Daerah yang diduga memiliki jenis tanah ekspansif adalah Desa Glagah agung Kecamatan Purwoharjo, Kabupaten Banyuwangi. Setiap pergantian musim, konstruksi bangunan selalu mengalami kerusakan terutama pada struktur dari bangunan. Pada musim penghujan tanah akan mengembang dan mengakibatkan bangunan terangkat, sedangkan pada saat kemarau tanah akan menyusut dan terjadi penurunan bangunan. Dalam menghadapi permasalahan yang terjadi maka perlu dilakukan treatment khusus untuk memperbaiki sifat tanah ekspansif. Salah satunya adalah stabilisasi kimiawi, dengan menambahkan bahan kimia untuk memperbaiki sifat tanah dan mereduksi potensi pengembangannya. pada peneliatian ini, stabilitator yang digunakan adalah kapur Ca(OH)2 dengan prosentase 4%,6%,8%,10%,12% dengan waktu peram (curing) selama 24 jam. Didapatkan hasil tanah menjadi tidak plastis seiring dengan bertambahnya kadar kapur. Penurunan indeks plastisitas didukung dengan pengujian gradasi butiran yaitu berkurangnya butiran fraksi lempung pada tanah yang dicampur dengan kapur menurut metode USCS dan metode AASHTO. Terjadi penurunan persen pengembangan primer tanah asli yang mulanya sebesar 11,9% berkurang menjadi 2,181% kadar kapur 4%, dan 0% pada kadar 6% hingga 12%.
THE COMPARISON OF ROAD DAMAGE VALUES BASED ON PCI (PAVEMENT CONDITION INDEX) METHOD OBSERVATION AND IRI (INTERNATIONAL ROUGHNESS INDEX) METHOD ON ROAD CLASS II IN LUMAJANG DISTRICT
Authors: Sari Devita , Sukmawati Sri , Hasanuddin Akhmad
Published: May 2020

Roads are a means of transportation that is often used by Indonesians to travel. Some class II road segments in Lumajang Regency include Tempeh-Sumberjati, Sumberjati-Karangrejo, Karangrejo-Yosowilangun, and Jalan Lintas Timur. The four sections are collector roads outside the city so that large vehicles often pass. Before handling the road, it must first be assessed on the condition of the pavement. The road surface condition assessment system uses the PCI method and the IRI method. The purpose of this study was to determine the condition of road damage and handling damage to the road so that the maintenance category was obtained. The IRI method is obtained from the Bina Marga Lumajang PU, while the PCI method is done visually. The average results of the four PCI methods are 76.54 with very good conditions and the IRI method is obtained 3.94 with good conditions so that both of these methods produce the same conclusions Maintenance for the PCI method and the IRI method uses routine maintenance, seen from both values.

Jalan merupakan sarana transportasi yang sering digunakan bagi warga Indonesia untuk berpergian. Beberapa ruas jalan kelas II di Kabupaten Lumajang antara lain Tempeh-Sumberjati, Sumberjati-Karangrejo, Karangrejo-Yosowilangun dan Jalan Lintas Timur. Keempat ruas tersebut merupakan jalan kolektor luar kota, sehingga sering dilewati kendaraan bermuataan besar. Sebelum dilakukan penanganan jalan, terlebih dahulu harus dilakukan penilaian kondisi perkerasan jalan. Sistem penilaian kondisi permukaan jalan menggunakan metode PCI dan metode IRI. Tujuan dari penelitian ini untuk mengetahui kondisi kerusakan jalan dan penanganan kerusakan jalan, sehingga didapatkan kategori pemeliharaan. Untuk metode IRI didapatkan dari PU Bina Marga Lumajang, sedangkan metode PCI dilakukan secara visual. Hasil rata-rata keempat ruas metode PCI sebesar 76,54 dengan kondisi sangat baik dan metode IRI didapatkan 3,94 dengan kondisi baik, sehingga kedua metode ini menghasilkan kesimpulan yang sama Pemeliharaan untuk metode PCI dan metode IRI menggunakan pemeliharaan rutin, dilihat dari kedua nilai.
Dynamics of Bcl-2Protein Phosphorylation: A Mini Review
Authors: Manan Abdul , Ilyas Sidra
Published: May 2020

The regulation of apoptosis depends upon the Bcl-2 protein family. The process of cell death and survival is highly complicated and regulated by various types of extrinsic as well as intrinsic network of biological system. Several enzymes and regulators play crucial role in cell death and survival cycle not only in healthy but also in pathological state particularly in cancer. In cancerous cells, various proto-oncogenes and anti-apoptotic proteins are activated and responsible for the cell survival and longevity. The mechanism of activation and inactivation of various proteins in cell survival is regulated by the process of phosphorylation (kinases) and dephosphorylation (phosphatases). The current review will summarize the dynamics of Bcl-2 phosphorylation and its role in apoptosis and cell survival.
Catalogue of Pests and Pathogens of Trees on the Island of Ireland
Authors: O'Hanlon Richard , Ryan Cathal , Choiseul James , Murchie Archie K. , Williams Christopher
Published: May 2020

Trees provide key ecosystem services, but the health and sustainability of these plants is under increasing biotic and abiotic threat, including from the growing incidences of non-native invasive plant pests (including pathogens). The island of Ireland (Ireland and Northern Ireland) is generally accepted to have a high plant health status, in part due to its island status and because of the national and international regulations aimed at protecting plant health. To establish a baseline of the current pest threats to tree health for the island of Ireland, the literature and unpublished sources were reviewed to produce a dataset of pests of trees on the island of Ireland. The dataset contains 396 records of pests of trees on the island of Ireland, the majority of pests being arthropods and fungi, and indicating potentially more than 44 non-native pest introductions. The reliability of many (378) of the records was judged to be high, therefore the dataset provides a robust assessment of the state of pests of trees recorded on the island of Ireland. We analyse this dataset and review the history of plant pest invasions, including (i) discussion on notable native and non-native pests of trees, (ii) pest interceptions at borders and (iii) pests and climate change. The dataset establishes an important baseline for the knowledge of plant pests on the island of Ireland, and will be a valuable resource for future plant health research and policy making.
Multi-Variable Stress Balancing Wireless Method Based on the Status of the Machines in the Cloud Spaces by Neural Networks
Authors: Zakeri Sedighe , Krishnasamy Karthikeyan , Gomathi Bernard
Published: May 2020

Cloud computations are based on the computer networks such as Internet which presents a new pattern to provide, consume and deliver services such as infrastructure, software, ground and other resources using network. The inappropriate timing of assigning loads to the virtual machines in the computational space could lead to unbalance in the system. One of the challenging planning problems. In the cloud data centers is considering both assigning and migration (transfer) of the virtual machines with the ability of reconfiguration and the integrated features of the hosting physical machines. In this article, we introduce an integrated and dynamic timing algorithm based on the Genetic evolution algorithm. The suggested method was evaluated based on these factors and different inputs. Our suggested method is done using Java programming language and cloud-SME simulation. The results show that the execution time and the response time were improved by 12 and 1 percent respectively.
Upaya Pengembangan Peternakan Sapi Potong Tanpa Limbah di Desa Bentangan Kabupaten Klaten
Authors: Sari Ayu Intan , Emawati Shanti
Published: May 2020

Farmer in managing their livestock business less attention to the impact on the environment. The purpose of this community empowerment activity is to especially for farmers and ranchers with the aim of increasing the added value of cattle dung into energy source and solve the problem of environmental pollution, improving public welfare through the cost-efficiency of energy supply and the cost of purchasing organic fertilizers. This activity is carried out in Bentangan village, Wonosari Sub-District, Klaten District. The program is as inclusive as possible group of partners in the implementation or use of Participatory Rural Appraisal (PRA) methods, through focus group discussions, counseling, technology transfer appropriate (installation of biogas and sewage treatment), training and demonstration. The results achieved are already carried out the construction of a biogas installation size of 9 m3 to accommodate faeces 6 cows that can be utilized as a source of 1 stove 2 furnaces, repair the cage floor, assembly and installation of a container of urine. The increased knowledge is shown from the increase in the pre-test and post-test scores 63 increased to 80,7, while the increase in motivation is shown by changes in the attitude of farmers who are increasingly open to environmentally friendly animal husbandry systems through the treatment of livestock manure. The effects of continuation from the IbM implementation, beef cattle farm and food crops would be environment friendly and zero waste.
Edukasi Kader dalam Upaya Pencegahan dan Penanggulangan Stunting di Kecamatan Mondokan Kabupaten Sragen
Authors: Lestari Anik , Hanim Diffah
Published: May 2020

Nowadays stunting has become the most observed on nutrition issues by the Indonesian government because stunting does not only cause physical abnormalities but also cognitive impairment in todlers so that as adults they will have low productivity. The aim of this community service was to increase the knowledge of certain community groups (health nutrition cadres) in preventing stunting in todlers. With the process of diffusion of knowledge, it is expected that there will be improvement in behavior of the target audience in carrying out their duties as posyandu cadres. This community service agenda are implemented through two activities. By having lectures and QnA sessions. The second method namely “cerdas cermat” was used to assess whether the counseling material can be understood by the participants. A team answer correctly they will be given a "door prize". The implementation of community service in the form of health education targeting Posyandu cadres in Mondokan Subdistrict, Sragen has been successfully implemented. The cadres were very enthusiastic to participate in the activity. This was indicated by their active participation in asking questions during lectures. In addition, during the game "cerdas cermat" was held, cadres can successfully answer questions related to the material "prevention of stunting". This educational activity needs to be followed up by "training" and "assistance", because if it is only given lecturing once it was feared that cadres could nott apply their new knowledge well.
Karakteristik Hasil Ultrasonografi Payudara pada Program Deteksi Dini Kanker Payudara di Kota Solo
Authors: Rahayu Rachmi Fauziah , Rospitasari Rospitasari , Prabata Adam , Maharina Luths
Published: May 2020

Breast cancer is the most common cancer found in women worldwide, including Indonesia. Breast cancer was the most second cancer-related death in Indonesia with 22,000 mortality cases in 2018. The high mortality rate is worsened by the fact that 80% breast cancer cases in Indonesia was detected when its already in advanced stage, so the morbidity and mortality rate will be high. In response to those problems, we held a community service activity which comprises counselling of breast self-examination (BSE) methods and free breast ultrasonography examination. Counselling was held to improve knowledge and awareness regarding breast cancer, whereas free breast ultrasonography examination was held to give access of one of breast cancer early detection method for community. We found 9 people (16.4% of all participants) who had breast lesion and 11 people (20.0% of all participants) who had lymph node involvement. The mean of age of the community service participants was 47.4 years old, so our community service program is right on the target, matching with the riskiest age group of breast cancer. Improving knowledge and awareness regarding the importance of early detection for breast cancer, then contributing to add breast ultrasonography examination data in Indonesia, especially at Solo, were the aim for this community service program.
Navigation-Assisted Balloon Eustachian Tuboplasty for Eustachian Tube Dilatory Dysfunction
Authors: Choi Sung-Won , Lee Seok-Hwan , Oh Se-Joon , Kong Soo-Keun
Published: May 2020

Objectives. Balloon Eustachian tuboplasty (BET) is a novel treatment method for Eustachian tube dilatory dysfunction (ETD). However, surgeons cannot identify the insertion depth of the catheter during BET, resulting in potential risks such as internal carotid artery (ICA) injury. Therefore, we developed an image-guided navigation balloon catheter to identify the insertion depth of the catheter and to establish awareness of the proximity of the ICA. This study aimed to evaluate the technical feasibility of this image-guided navigation balloon catheter system in patients with ETD.Methods. Twenty-nine patients (38 ears; nine bilateral; 21 right ears, and 17 left ears) diagnosed with ETD were assessed. All patients who showed no improvement despite medical therapy with topical steroids, anti-reflux medication, and the Valsalva maneuver for a minimum of 6 weeks received image-guided navigation-assisted BET. The 7-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) score and Valsalva maneuver were used to evaluate patients’ symptoms preoperatively and at the postoperative follow-up.Results. Image-guided navigation-assisted BET was safely performed in all patients. The mean total ETDQ-7 score was 25.4±7.1 preoperatively, 17.5±6.2 at 1 month, and 15.2±7.0 at 6 months (P<0.001). In total, a Valsalva maneuver was possible for 28 of 38 ears (73.7%) at the time of the patient’s final visit at 6 months post-procedure.Conclusion. Image-guided navigation balloon catheters are a potentially valuable tool in patients with ETD. Their use is also technically feasible and safe when performing BET to treat ETD.
Effects of Periosteal Elevation Before Lateral Osteotomy in Rhinoplasty: A Meta-Analysis of Randomized Controlled Trials
Authors: Kim Ji-Sun , Kim Sun Hong , Lee Hyesook , Kim Byung Guk , Hwang Se Hwan
Published: May 2020

Objectives. Although osteotomy is an important part of rhinoplasty, it is known to be closely related to postoperative eyelid edema and ecchymosis. We aimed to evaluate the effects of periosteal elevation prior to osteotomy on eyelid edema and ecchymosis.Methods. Two authors reviewed studies in the Medline, Scopus, and Cochrane databases published through May 2019. Randomized controlled trials comparing periosteal elevation (subperiosteal tunneling) with periosteal preservation that reported eyelid edema or ecchymosis or subconjunctival hemorrhage as outcomes of interest were included. From each study, the baseline characteristics of the study subjects, the quality of the study, the number of patients in the treatment and control groups, and outcomes were extracted.Results. Data for meta-analysis were identified in six studies with a total of 208 patients. Eyelid ecchymosis and edema within 3 days postoperatively were significantly more common in the periosteal elevation group than in the preservation group, although such an association was not found for edema on postoperative day 7 (standardized mean difference [SMD], 0.21; 95% confidence interval [CI], –0.09 to 0.50; I2 =0%). There was no significant difference in subconjunctival hemorrhage on day 1 (SMD, 0.31; 95% CI, –0.09 to 0.72; I2 =0%).Conclusion. Periosteal preservation during lateral osteotomy may reduce eyelid edema and ecchymosis compared to periosteal elevation. Further studies with rigorous research methods should be carried out to determine the effectiveness of different techniques in lateral osteotomy.
De Gata Borralheira À Cinderela: Mas Nem Tudo É Conto De Fadas No Processo Sucessório de uma ONG
Authors: Sousa Cecílio Larissa Sousa , Godói-de-Sousa Edileusa , Bueno Mendonça Juliana Moro
Published: May 2020

A Sra. Maria de Lourdes teme o futuro. Seu antigo cargo nunca significou nada, agora a Associação dos Artesãos de Uberlândia está em suas mãos. Ela não queria assumir as responsabilidades, mas não abandonaria a associação. Nenhum associado pensava sobre os impactos do processo sucessório, nunca ouviram sobre a necessidade de planejar esse processo ou sobre as habilidades para lidar com crises na sucessão. A análise do caso objetiva: discutir a importância do planejamento da sucessão nas organizações, focando nos empreendimentos sociais, conscientizar sobre a importância de se agir de maneira ética e transparente, e instigar debate sobre o dilema do caso.
Hegemonia do Planejamento Urbano Estratégico e o Discurso Contra-Hegemônico do Direito à Cidade
Authors: Leandro Santos Jouberte Maria , Carvalho Benício de Melo Sérgio Benício
Published: May 2020

O presente trabalho teve por objetivo avaliar os argumentos que constituem os diferentes discursos acerca do Planejamento Urbano e o Direito à Cidade tendo como foco a construção de um Grande Projeto Urbano (GPU) denominado “Novo Recife”. Para tal, acessamos três posições discursivas sobre o assunto: das empresas que formam o consórcio responsável pela construção, da Prefeitura do Recife e de um movimento social organizado denominado Direitos Urbanos (DU). O método adotado foi a arqueologia foucaultiana e sua análise de discurso. Nossos achados apontam para cinco formações discursivas antagônicas: duas favoráveis e três contestadoras do modelo de planejamento urbano adotado no Recife.

Palavras-chave: Gestão Pública, GPU, Urbanismo Crítico
Transparência e Dados Abertos Governamentais: Possibilidades e Desafios a Partir da Lei De Acesso À Informação
Authors: Possamai Ana Júlia , De Souza Vitoria Gonzatti
Published: May 2020

O paradigma dos dados abertos governamentais vem ganhando espaço na gestão pública brasileira, tendo sido incorporado ao direito de acesso à informação, componente fundamental para o exercício da participação nas poliarquias. Sendo assim, o artigo objetiva analisar as possibilidades e os desafios institucionais à implementação desse paradigma no Brasil, a partir da Lei de Acesso à Informação. São estudados os pedidos de acesso à informação realizados aos órgãos públicos federais, as respostas conferidas, bem como os recursos julgados em última instância, durante momentos anterior e posterior à edição da Política de Dados Abertos, em maio de 2016. São empregadas estatísticas descritivas simples e técnicas de análise de conteúdo para categorizar os pedidos/respostas segundo termos de interesse e tratamento conferido pelos órgãos. Os resultados evidenciam um espaço “cinzento” criado pelas hipóteses legais de restrição de acesso à informação, as quais amparam o não atendimento de pedidos de abertura de dados.
Attitude of Nursing Students towards Internet Plus Nursing Service
Authors: Zhao Hua , Zhao Peng , Wang yanni
Published: May 2020

Background: In 2019, China completed the pilot project “Internet Plus Nursing Service.” As undergraduate nursing students are the future of nursing, their attitude, willingness, and motivation toward “Internet Plus Nursing Service” deserves study. The study aimed to investigate the attitude, willingness, and motivation of third-year undergraduate nursing students toward “Internet Plus Nursing Service,” providing a reference for the development of “Internet Plus Nursing Service” and related nursing education. Methods: This cross-sectional study comprised 508 third-year undergraduate nursing students from a public University of Traditional Chinese Medicine, using a self-designed survey. Results: Most students held a positive attitude towards “Internet Plus Nursing Service,” and were willing to choose “Internet Plus Nursing Service” as their future career choice. Conclusion: School education should develop a diversified nursing service model and professional training programs that meet social demands and professional needs, as well as address the opportunities and challenges of the Internet era.
Combination of epidural spinal cord stimulation and treadmill training with body weight support attenuates spasticity in adult rats with spinal cord transection
Authors: Saito Junya , Koda Masao , Furuya Takeo , Iijima Yasushi , Kitamura Mitsuhiro , Miyamoto Takuya , Kai Chihiro , Orita Sumihisa , Inage Kazuhide , Yamazaki Masashi , Ohtori Seiji
Published: May 2020

Background

The neural control of rhythmical hindlimb locomotion is known to be organized by a central pattern generator (CPG) in the lumbar enlargement. In the previous report, epidural spinal cord stimulation (SCS) for CPG with treadmill training facilitated restoration of locomotion in patient with motor incomplete spinal cord injury. However, the precise mechanism of improvement is still unclear. The purpose of this study was to elucidate efficacy and molecular mechanism of SCS with treadmill training.
Methods

Ten female Sprague-Dawley rats were used in this study. The rats were housed with food and water under a 12 h/12 h light-dark cycle. We performed spinal cord transection at the T8-T9 level. After two weeks, the rats were divided into SCS group and control group. The rats in SCS group were performed implantation of an electrode at L2 level. SCS and body weight support treadmill training were performed for 30 minutes per day, 5 days per weeks, for 4 weeks. The rats in the control group were performed treadmill training without stimulation for same period. We evaluated hind-limb locomotor function by using Basso-Beattie-Bresnahan (BBB) score. We also assessed resistance force for full extension of hindlimb as evaluation of spasticity. For histological examination, we performed immunostaining for glutamic acid decarboxylase-65 (GAD65) of lumbar enlargement after behavioral assessment.
Results

There was no significant difference of BBB score between two groups, but spasticity of hind-limb in SCS group was significantly reduced. Histological assessment revealed that expression of GAD65 tended to increase in the SCS group
Conclusions

SCS ameliorated hindlimb spasticity. It was suggested that up-regulation of GAD65 involved suppression of spasticity.
A prospective long term observational clinical study to evaluate the significance of manual tooth brushing on gingival recession
Authors: Dhaifullah Esam , Pradeep koppolu , Kalakonda Butchibabu , Elkhatat Esam
Published: May 2020

Purpose:Gingival recession (GR) is a common finding in adult populations associated with varied etiologies. The aim of our study was to correlate the influence of tooth brushing on GR. Further, it was intended to evaluate the role of a corrective tooth brushing technique with proper oral hygiene instructions on progression/regression of GR on a long term (3 years) follow up.Methods:A total of 53 healthy subjects, male and female, 18 to 52 years of age, without any boneloss were examined. A questionnaire evaluated all the variables associated with tooth brushing in these subjects. Later, patients were instructed on Modified Stillman brushing technique and oral hygiene instructions were reinforced. All the parameters were measured by two trained calibrated examiners at the baseline and at 6 month intervals.Results:Majority of the subjects with GR at the first visit used hard toothbrush bristle (62.2%), brushed their teeth twice daily (56.7%) and did not know the correct technique of tooth brushing (83.1%). Those subjects with buccal recession evident in the first visit who maintained high standard of oral hygiene as per our instructions and had followed the correct brushing technique as advised, it was observed that GR progressed only at the following teeth: the first and second right mandibular premolars, right mandibular canines, left mandibular canines and first left maxillary molars (total 17. 9%).Conclusion:The results of our study validate that the various variables associated with tooth brushing such as type of tooth brush, type of tooth brushing technique and frequency of tooth brushing have a potential role that result in GR. Moreover, a correct tooth brushing technique together with good oral hygiene prevents further recession.
A Study of the Prediction of Bowel Resection due to Strangulated Small Bowel Obstruction
Authors: Udaka Tetsunobu , Taniguchi Atsuki , Kouzai Jun , Ootsuka Tomoaki , Watanabe Nobuyuki , Endou Izuru , Yoshida Osamu , Asano Hiroaki , Kubo Masatoshi
Published: May 2020

Background

In this retrospective study, we aimed to assess the predictive factors for bowel resection due to strangulated small bowel obstruction (SSBO).
Methods

We enrolled a total of 109 patients diagnosed with SSBO at surgery. They were divided into two groups: those who underwent bowel resection and those who did not. The clinical findings, blood test results, blood gas analysis results, computed tomography (CT) findings, and sequential organ failure assessment (SOFA) scores of the patients were examined and compared between the two groups.
Results

The 109 patients were divided into the bowel resection group (n = 38) and non-bowel resection group (n = 71). A univariate analysis indicated significant predictive factors to be a history of abdominal surgery, prolonged time from the onset of disease to the operation, increased C-reactive protein (CRP) level, decreased albumin, SOFA score, existence of closed-loop obstruction, and reduced enhancement of the intestinal wall at CT. A multivariate analysis indicated that a reduced enhancement of the intestinal wall and the existence of closed-loop obstruction were independent predictive factors. Strangulated bowel obstruction can progress to a serious condition. It is therefore crucial to predict preoperatively those patients who are likely to require bowel resection.
Conclusions

Assessing the reduced enhancement of the intestinal wall and the existence of closed-loop obstruction are required in order to determine whether or not resection of the incarcerated intestine with SSBO is necessary.
A single centre study assessing the effectiveness of active monitoring, using telemedicine, in preventing heart failure admissions and death in a primary care population with systolic heart failure.
Authors: Bowers Nicola , Lodge Ben , Clifford Charlie , Monti Ricardo Pio , Phippen Marc , Clifford Piers
Published: May 2020

BackgroundPatients with systolic heart failure are at high risk of admission to hospital and death. This can be reduced by ensuring that they are receiving all evidence-based heart failure medications and by detecting early signs of deterioration in their condition.MethodsWe recruited 209 primary care patients with echocardiographically proven left ventricular systolic dysfunction (ejection fraction < 40%). 84 patients consented to be actively monitored by the heart failure team using telemedicine. 125 patients consented to receiving usual care but allowing access to their medical records. The primary end-point was cardiovascular death or admission to hospital for heart failure at 1 year. Secondary end-points included the prescription of evidence-based heart failure medications and patient satisfaction at the end of the study.ResultsThere was no difference in the mortality rate between the groups (6.02% in the active group and 5.56% in control). There was a significant difference in hospital admission (10.84% in the active group and 1.59% in control; p-value of 0.0078). At the end of the study, in the active group v control group, 92% v 52% of patients were on a beta-blocker, 92% v 48% on ACE-I/ARB, and 60% v 30% on an MRA. There were no differences in the final doses achieved.ConclusionsActive telemonitoring in an elderly population with systolic heart failure did not reduce cardiovascular mortality or admission to hospital for heart failure over the 1 year of the study. It did result in more patients receiving evidence based heart failure medications.Trial registrationThis trial received ethical approval from the Health Research Authority London-City Road and Hampstead Research Ethics Committee (REC Reference: 16/L0/0070, IRAS project ID: 173818). The ClinicalTrials.gov Identifier number is: NCT04371731. This trial was retrospectively registered on 30/4/2020 and this study adheres to CONSORT guidelines
Epileptic Spasms at Muhimbili National Hospital Tanzania, A Retrospective Study.
Authors: Mwalongo Joseph , Kija Edward
Published: May 2020

Background; Epileptic spasms (ES) is an epileptic encephalopathy occurring during infancy and early childhood. Early recognition and management is important to prevent severe neurological impairment. This study aimed at describing the clinical presentation, management and outcome of patients with Epileptic Spasms attending Muhimbili National Hospital (MNH), in Dar Es Salaam, Tanzania. Methods; A retrospective cross sectional study of all patients diagnosed with epileptic spasms was conducted at MNH from July 2016 to October 2018. Results; A total of 40 patients diagnosed with epileptic spasms were retrieved with male to female ratio of 3:2. In this study, 17 (42.5%) patients had a documented history of perinatal insult. The median age of onset of spasms was 5 months (IQR 1–12 months). In 14 (80%) out of 17 patients whom electroencephalography ( EEG) findings were retrieved had abnormal EEG findings showing either generalized epileptiform discharges 7(41%), generalized slowing 5(30%), hypsarrthymia 1(6%), or abnormal focal epileptiform discharges 2 (12%). Twenty-nine (73%) received prednisolone, with a median time of spasms subsiding of 1 month with a range of 10 days to 3 months in about 90% of them. Conclusion; The median age of onset of epileptic spasms at MNH is 5 months with the most common cause being perinatal insult in more than 40% of the patients. High dose prednisolone showed a good response in patients with epileptic spasms at MNH.
Theoretical and experimental study on the effective area of water film and dust removal efficiency
Authors: guo hua , Wang hai qiao , Chen shi qiang , Wu zhi rong
Published: May 2020

We investigate the capture process of dust flow through a vibrating wire, water fog, and a water film to address the problem of excessively high exhaust dust concentrations in mine exhaust shafts according to the theory of liquid-solid flow and capillary film formation. Functional expressions of the thickness and height of dust-trapping water film are derived by using Young-Laplace equations and Navier-Stokes equations, respectively. The theoretical relationship between the effective water film area and dedusting efficiency on a vibrating wire is obtained.The dedusting efficiency of a resonant chord grid is measured experimentally.The results show that wire spacing plays a decisive role in water film formation.The instantaneous effective water film area of the vibrating wire grid is proportional to the dedusting efficiency. When the diameter distance ratio of the resonance chord grid was 1.14 with the dedusting wind speed controlled at 3 m/s and a spray pressure of 0.7 MPa. The total dust control efficiency can reach > 92%.