bluuebunny/crossref_metadata_2025 huggingface dataset:
Teletandem e literatura: experiências interculturais no ensino de português como língua estrangeira
Authors: Silva Mayara Nunes da , Ramos Karin Adriane Henschel Pobbe
Published: November 2022

O Teletandem caracteriza-se como um contexto telecolaborativo de aprendizagem de línguas e tem se desenvolvido como um ambiente propício para a difusão de língua, literatura e cultura (Telles, 2015a; Zakir, 2015; Ramos & Carvalho, 2020). Ao promover a interação entre estudantes brasileiros e estudantes de universidades estrangeiras, o teletandem proporciona o aprendizado de outro idioma para os interagentes e contribui para a divulgação do ensino de Português como Língua Estrangeira (Ramos, 2016). Desse contato, os participantes de tandem podem desenvolver ainda uma perspectiva intercultural que abrange os modos de ser e de agir socialmente na língua (Mendes, 2011; Kramsch, 2017). Assim, partindo de uma abordagem intercultural de base discursiva, compreendemos cultura como processos históricos, construídos na interação entre sujeitos que podem não mais se identificar necessariamente pelas suas nacionalidades, mas também, por seu gênero, sua raça, etnia e idade, afetando, consequentemente, seus modos de usar a língua e construir significado (Kramsch & Hua, 2016). Diante disso, este artigo tem como objetivo apresentar algumas reflexões, resultantes dos dados iniciais da nossa pesquisa de mestrado, sobre as contribuições da discussão de textos literários, em interações de tandem, para o desenvolvimento de um ensino intercultural da língua portuguesa que leve à compreensão da dimensão simbólica das trocas interculturais, bem como a uma compreensão mais ampla e diversa de cultura. Para tanto, realizamos, inicialmente, uma apresentação do projeto teletandem e a sua importância para a difusão do ensino do Português como Língua Estrangeira. E, após, explicamos a abordagem intercultural de base discursiva, relacionando-a com o ensino de língua estrangeira, para demonstrar a relevância da literatura nesse contexto de aprendizagem. Os resultados preliminares indicam que a inserção de textos literários nas sessões de teletandem possibilita um aprofundamento nas discussões e o surgimento de temas mais diversos e diretamente relacionados às realidades dos interagentes.
Tecendo o cenário geopolítico e sociolinguístico: capítulos da obra
Authors: Nunes Rosana Helena , Silva Kleber Aparecido da
Published: November 2022

A resenha objetiva apresentar a obra “O português no século XXI: Cenário geopolítico e sociolinguístico, do estudioso e linguista Luiz Paulo de Moita Lopes, publicada em 2013, pela Editora Parábola. Contrastes, diversidade, heterogeneidade linguística sempre representaram o percurso histórico dos estudos linguísticos. Desde o surgimento da ciência da linguagem, Ferdinand de Saussure (1916) já entendia o estudo da língua e linguagem, ao considerar a linguagem como heteróclita, porém não era possível estudá-la por meio de um modelo estruturalista. Xoán Lagares (2018), em seu livro “Qual política linguística? desafios glotopolíticos contemporâneos, refere-se à linguagem como um campo de luta, um ativismo linguístico. Paulo Freire (1992, p.78), em estudos realizados, reconhece que “[...] os colonizados jamais poderiam ser vistos e perfilados pelos colonizadores como povos cultos, capazes, inteligentes, imaginativos, dignos de sua liberdade, produtores de uma linguagem que, por ser linguagem, marcha e muda e cresce histórico-socialmente”. O filósofo assevera que “[...] os colonizados [...] falam dialetos fadados a jamais expressar a ‘verdade da ciência’, 'os mistérios da transcendência’ e a 'boniteza do mundo”. Assim, busca-se, na apresentação da resenha trazer à baila conceitos aprofundados pelos autores da obra, no que concerne ao português do século XXI, as interfaces que direcionaram os estudos da língua portuguesa, a perspectiva histórica, geopolítica e etnográfica, representada pelos quatro continentes em que a língua portuguesa deixou sua “passagem”, quando da colonização portuguesa e o que isso trouxe como consequência para o século XXI
International Brand Development: Importance Placed on Internal Factors by Sri Lankan Companies
Authors: Palipane Dhilmini K.
Published: November 2022

With increasing globalization and competition. international brand development has become a crucial activity for firms. Although Sri Lankan companies have long been involved in exporting, and in branding for the local market, a few successful international brands have been developed. This research examines the perceptions of employees concerning the importance of internal (intra-organizational) factors in international brand development. A survey was carried out amongst employees in companies which had developed international brands and in those which had not. Key differences and similarities emerged between the two categories. The findings indicate the importance or managers devoting more attention to internal factors, which would be of use in developing international brands.
The Role of Corporate Governance in the Economic Development
Authors: Senaratne Samanthi , Gunaratne P. S. M.
Published: November 2022

This paper presents a review of extant literature on corporate governance with a specific focus on its development impact. The paper finds that much of modern corporate governance literature is focused on the publicly held companies which are premised on the separation of ownership and control between shareholders and managers. However, it has been subjected to a paradigm shift from the stewardship theory-agency theory-stakeholder theory over the years widening the accountability of a company to encompass all its stakeholders not only the shareholders. The paper finds that effective corporate governance, benefits companies through greater access to financing, lower cost of capital and improved performance. This indicates that better corporate governance increases the likelihood that companies will satisfy the legitimate claims of all stakeholders and fulfil their social responsibilities ensuring the long-term, sustainable growth of companies, which is necessary for the economic development of a country.
Recognizing Violence against Women as an Obstacle to Organizational Peace and Development: A New Vision for an Old Issue
Authors: Handapangoda Wasana S.
Published: November 2022

Violence against women takes a variety of forms, extending from domestic abuse to violence in workplace. It is an ancient, universal problem occurring in every culture and social group. However, major traditions of organizational analysis have not devoted significant and explicit concern with gender. sexuality and violence. Accordingly, the objectives of this paper are twofold; to recognize the most frequent types or organizational violence against women and the impact of such organizational violence on their work-lives and thereby the overall performance and peace of the organization. The methodology adopted has been qualitative and based on case study approach, confined to one public sector organization in Sri Lanka. The study shows how complex the issue of gender-based violence in organizations is. It confirmed that organizational violence seriously affects mental health of the working women concerned, which eventually create a deterioration of the work culture, peace and development in the organization.
Analgesic effect of ketorolac added to lidocaine in surgery of traumatic arm injuries: A double-blind, randomized clinical trial
Authors: Amini Afshin , Farbod Arash , Eghbal Mohamad Hosein , Ghadimi Maryam , Shahriyari Ensiyeh
Published: November 2022

Acute pain after surgery can cause harmful effects. There are many ways to treat pain after surgery. Bier block technique is also a type of intravenous regional anesthesia that is suitable for short and minor surgeries of the arm, wrist, and fingers, so this study aims to compare the analgesic effect of Ketorolac in intravenous injection and when the lidocaine is added to Bier block. In surgery, traumatic injuries to the upper limbs. This study was a clinical trial, randomized and double-blind. The target population was candidates for upper limb orthopedic surgery. The patients selected based on the entry and exit criteria were randomly assigned to one of the 3 study groups. The intensity of pain, the amount of morphine consumed through the intravenous PCA pump, the incidence of side effects of morphine and ketorolac, as well as the overall patient satisfaction regarding the anesthesia method and pain control were compared between the groups. Data analysis, both descriptive and analytical, was done using SPSS statistical software version 21. The three studied groups were identical and had no differences in terms of quantitative and qualitative demographic variables. The median tourniquet closing time is different between the control group and the intravenous ketorolac and topical ketorolac groups with P=0.002 and P=0.001, respectively. There was no significant difference between the three groups in terms of the time of the first request to receive painkillers after deflating the tourniquet, but the amount of morphine received between the groups was significantly different (P=0.02). Comparison of pain intensity based on NRS, considering Taking the measurement repetition times indicated the significance of the effect of pain intensity between the groups (P=0.001). In terms of overall satisfaction with the quality of analgesia and anesthesia method, no significant difference was observed between the three study groups. In terms of the occurrence of complications related to the use of ketorolac, no complications were observed in any of the groups receiving this drug.

In general, by conducting this study, it can be said that the administration of Ketorolac reduces the intensity of postoperative pain in the recovery room and transfer to the inpatient ward, and reduces the amount of morphine received by patients, but the time of the first request for pain relief by the patient It does not significantly delay and does not affect the overall satisfaction of patients with the quality of analgesia during and after the operation and their satisfaction with the anesthesia method they received
Immunoexpression of p53 mutant-type in Iranian patients with primary and recurrence oral squamous cell carcinoma
Authors: Daneste Hossein , Sadeghzadeh Azita , Mokhtari Maral , Mohammadkhani Hossein , Lavaee Fatemeh , Moayedi Javad
Published: November 2022

Mutations in tumor suppressor p53 protein can occur at different phases of malignant transformation and affect the patient's prognosis. This study aimed to evaluate the expression of mutant p53 protein in Iranian patients with the primary and recurrence oral squamous cell carcinoma (OSCC). This retrospective cross-sectional study conducted on a group of patients with the primary OSCC (n=122) and the control subjects with oral noncancerous reactive lesions (n=80). Immunohistochemistry was performed with the DO-7 monoclonal antibody against p53 protein, and samples with ≥10% immunostaining were considered positive. Statistical analyses were carried out using SPSS. Positive staining for p53 was observed in none of the control subjects and 57.4% (70 of 122) of the primary OSCC patients (p<0.0001, OR=107.69, 95%CI=6.49-179.0). The p53 immunopositivity had no significant differences between males and females (54.2% vs. 62%, p=0.390), but significantly different between those aged below and over 50 years (p<0.0001, OR=4.52, 95%CI=1.07-12.05). During follow-up, OSCC recurrence occurred in 104 patients, but the phenotype of the mutant p53 protein in patients who relapsed was the same as in matched primary tumors (p=0.763). Risk of recurrence had no significant differences between p53-positive and p53-negative cases (p=0.953), males and females (p=0.263), and age below and over 50 years (p=0.223). Despite its confirmed diagnostic value, the immunoexpression of the p53 mutant protein in OSCC in cancer recurrence was the same as in the primary tumor. However, further studies with a larger sample size and longer follow-up are needed to confirm or change our conclusions.
Nigrosome and Neuromelanin Imaging as Tools to Differentiate Parkinson's Disease and Parkinsonism
Authors: Biswas Deblina , Banerjee Rebecca , Sarkar Swagata , Choudhury Supriyo , Sanyal Pritimoy , Tiwari Mona , Kumar Hrishikesh
Published: November 2022

Parkinson's disease (PD) lacks a definitive diagnosis due to a lack of pathological validation of patients at antemortem. The risk of misdiagnosis is high in the early stages of PD, often eluded by atypical parkinsonian symptoms. Neuroimaging and laboratory biomarkers are being sought to aid in the clinical diagnosis of PD. Nigrosome imaging and neuromelanin (NM)-sensitive magnetic resonance imaging (MRI) are the new emerging tools, both technically simple plus cost-effective for studying nigral pathology, and have shown potential for authenticating the clinical diagnosis of PD. Visual assessment of the nigrosome-1 appearance, at 3 or 7 Tesla, yields excellent diagnostic accuracy for differentiating idiopathic PD from healthy controls. Moreover, midbrain atrophy and putaminal hypointensity in nigrosome-1 imaging are valid pointers in distinguishing PD from allied parkinsonian disorders. The majority of studies employed T2 and susceptibility-weighted imaging MRI sequences to visualize nigrosome abnormalities, whereas T1-weighted fast-spin echo sequences were used for NM imaging. The diagnostic performance of NM-sensitive MRI in discriminating PD from normal HC can be improved further. Longitudinal studies with adequate sampling of varied uncertain PD cases should be designed to accurately evaluate the sensitivity and diagnostic potential of nigrosome and NM imaging techniques. Equal weightage is to be given to uniformity and standardization of protocols, data analysis, and interpretation of results. There is tremendous scope for identifying disease-specific structural changes in varied forms of parkinsonism with these low-cost imaging tools. Nigrosome-1 and midbrain NM imaging may not only provide an accurate diagnosis of PD but could mature into tools for personally tailored treatment and prognosis.
Vernix caseosa peritonitis following vaginal delivery
Authors: Abdullah Arif , Jusoh Asri Che , Samat Noryani Mohd , Jais Murni Hartini
Published: November 2022

The incidence of the acute abdomen during early postpartum is not uncommon. In this report, we highlight an extremely rare cause of acute abdomen which posed significant diagnostic and management dilemmas. In this case, the patient presented at day 5 postvaginal delivery with progressive respiratory embarrassment, mild abdominal pain, and fever. Her clinical signs, blood and laboratory parameters, and imaging (ultrasound and computed tomography scan) were however nonspecific except for worsening ascites. Laparotomy was determined as the best procedure for her in view of her polymorphonuclear cell count from an abdominal paracentesis being very high and the absence of clinical improvement even with the best intensive care support. Vernix caseosa peritonitis (VCP) was finally diagnosed based on histological examination of the “cheesy” slough extracted intraoperatively. Our case illustrates the nonspecific features of VCP which may be potentially fatal if undiagnosed early and no definitive care is provided.
The lumbar hernia
Authors: Dagar Abhishek , Hurria Naman , Chandrakar Saurabh , Tanwar* Manjit , Gupta Sandhya , Sinha Ajit
Published: November 2022

Lumbar hernias are rarely encountered as compared to other ventral abdominal wall hernias and are often misdiagnosed and overlooked. They account for less than 1.5% of all abdominal hernias. Fewer than 300 cases have been reported over the past 300 years. A lumbar hernia is defined as a protrusion of intra-abdominal contents through a weakness or rupture in the posterior abdominal wall. It must be distinguished from a lipoma, cold (tuberculous) abscess or a pseudo-hernia due to local muscular paralysis. Presenting a case of 65-year-old female who came to surgery OPD with complaint of a swelling in the right lumbar area since 5 years. On examination, a smooth and non-tender swelling measuring approximately 4 x 3 cm was evident in right lumbar region. We proceeded with a lumbar ultrasound which confirmed the presence of the hernia in posterior abdominal wall. Later, the patient was admitted for surgery under spinal anaesthesia. An open approach was performed and intraoperative findings revealed retroperitoneal fat, intermuscular lipoma and a small hernia sac as contents of swelling. It is very unusual to find lumbar hernias presenting with a lipoma, as in our case, the clinical findings alone can be very confusing and increase the chances of incorrect diagnosis and subsequent treatment. Inability of clinical examination and ultrasonography alone in making an adequate diagnosis of lumbar hernia in preoperative setting mandates a routine CT/MRI for all such patients, to ensure surgeons have a correct diagnosis before proceeding for surgery. Ideal management is just like other hernias, i.e., with mesh hernioplasty either laparoscopically or through an open approach.
Highlighting the Role of Nurses
Authors: Kumar Rajesh
Published: November 2022

The coronavirus pandemic brought new challenges and opportunities for health professionals, including nurses and nursing students. Nurses worked as front-line warriors to fight against COVID-19 worldwide. They worked round the clock to deliver the best possible care to critically ill patients admitted in critical care areas and use ventilators. Therefore, many national and international agencies, including the World Health Organization (WHO), the International Council of Nurses (ICN), and the United Nations (UN) body, have acknowledged the hard work of nurses during the pandemic. This document highlights nurses' diverse roles and responsibilities during the ongoing COVID-19 pandemic. Reflection on their work will further help policymakers support nursing professionals fighting against the virus and putting themselves at inevitable risk of coronavirus.
Decidability problem for exponential equations in finitely presented groups
Authors: Bogopolski Oleg , Ivanov Aleksander
Published: November 2022

We study the following decision problem: given an exponential equation
$a_1g_1^{x_1}a_2g_2^{x_2}\dots a_ng_n^{x_n}=1$
over a recursively presented group G, decide if it has a solution with all
$x_i$
in
$\mathbb {Z}$
. We construct a finitely presented group G where this problem is decidable for equations with one variable and is undecidable for equations with two variables. We also study functions estimating possible solutions of such an equation through the lengths of its coefficients with respect to a given generating set of G. Another result concerns Turing degrees of some natural fragments of the above problem.
Green function for linearized Navier–Stokes around a boundary shear layer profile for long wavelengths
Authors: Grenier Emmanuel , Nguyen Toan T.
Published: November 2022

This paper is the continuation of a program, initiated in Grenier and Nguyen [SIAM J.
Math. Anal. 51 (2019); J. Differential Equations 269 (2020)], to derive pointwise estimates on the
Green function of Orr–Sommerfeld equations. In this paper we focus on long wavelength perturbations, more precisely horizontal wave numbers

\alpha

of order

\nu^{1/4}

, which correspond to the lower boundary of the instability area for monotonic profiles.
Proper biharmonic maps on tangent bundle
Authors: Djaa Nour Elhouda , Latti Fethi , Zagane Abderrahim
Published: November 2022

This paper, we define the Mus-Gradient metric on tangent bundle $TM$ by a
deformation non-conform of Sasaki metric over an n-dimensional Riemannian
manifold $(M, g)$. First we investigate the geometry of the Mus-Gradient metric
and we characterize a new class of proper biharmonic maps. Examples of proper
biharmonic maps are constructed when all of the factors are Euclidean spaces.
General Terms of All Almost Balancing Numbers of First and Second Type
Authors: Tekcan Ahmet , Erdem Alper
Published: November 2022

In this work, we determined the general terms of all almost balancing numbers
of first and second type in terms of balancing numbers and conversely we
determined the general terms of all balancing numbers in terms of all almost
balancing numbers of first and second type. We also set a correspondence
between all almost balancing numbers of first and second type and Pell numbers.
VINE VARIETIES FOR WHITE WINES IN THE CLIMATE CONTEXT OF THE ODOBESTI VINEYARD, ROMANIA
Authors: BOSOI Ionica , Rotaru Liliana , PUȘCALĂU Marioara , Colibaba Cintia
Published: November 2022

Odobeşti Vineyard is one of the most famous and oldest Romanian vineyards, with a focus on white wines. To improve the existing assortment of varieties over time at the Research and Development Station for Viticulture and Vinification, Odobesti (RDSVV, Odobești), four vine varieties were obtained and approved: ʹŞarbaʹ (1972), ʹBăbească griʹ (1975), ʹMioriţaʹ (1980) and ʹVranceaʹ (2018), with superior quality and productive potential and a high capacity to capitalise on the edaphoclimatic conditions specific to this viticultual area. This study presents the behaviour of these varieties of vines in the climatic conditions of the Odobesti Vineyard in the period 2017–2021. The following parameters were studied and determined: the phenological spectrum of the vine, fertility and productivity (% fertile shoots, fertility coefficients, productivity indices), quantity and quality of grape production (grapes/vine, average bunch weight, grape production/vine, sugar content, total acidity and glucoacidimetric index). The data obtained were compared with the ʹSauvignon Blancʹ variety, which is widely grown in this area. The evolution of the vegetation phenophases was conditioned by the climatic factors during the study period. There was a tendency to shorten them due to the increase in air temperature values. The variety ʹVranceaʹ presented a high fertility potential (89.5% fertile shoots), the varieties ʹBăbească griʹ and ʹMiorițaʹ showed a higher productive potential than the control variety ʹSauvignon Blancʹ (6.06–6.12 kg/vine), and the variety ʹȘarbaʹ recorded the highest accumulations in sugars (230.5 g/L). In the climatic context of the Odobești Vineyard, the white wine varieties ʹȘarbaʹ, ʹBăbeasca griʹ, ʹMiorițaʹ and ʹVranceaʹ have demonstrated a valuable agrobiological and technological potential, comparable to that of the ʹSauvignon Blancʹ variety.
PSYCHOLOGICAL ANALYSIS OF THE PROBLEM OF WOMEN'S SOCIAL ACTIVITY IN THE CONTEXT OF FAMILY STABILITY
Authors: Harutyunyan Narine
Published: November 2022

The article is devoted to problem of the social role, status and activity of a modern woman. Since the middle of 20th century the problem became the subject of research in the context of family stability in which the main role was given to the spouse’s vision of woman’s social activity. The social activity is considered as an external function of family and includes social, political, educational, professional orientation, intellectual merits, skills and abilities, i.e. the activity of spouses outside the family. It gives the satisfaction of needs that are practically impossible to meet within the family.

We have studied the hierarchy of family values ​​from the aspect of stability and the ways of expectations and ambitions of 120 families (women-men, n = 240) during the implementation of functions, their relevance within the economic, parenting, social activity, emotional spheres and in external attractiveness. The results of the research allow us to consider the equal distribution of responsibilities of social activity of the spouses as the main precondition for family stability.  According to research results, the relatively high rate of social activity of a person/spouse in a system of value hierarchy proves that this function is one of the important factors for strengthening and stabilizing the family relationships.
Mas Nganten's Discourse in Gadis Pantai Novel Works by Pramoedya Ananta Toer (Michel Foucault’s Critical Discourse Perspective)
Authors:   Pendidikan Bahasa dan Sastra Indonesia, IKIP Budi Utomo Malang, Indonesia, Ahmad Harun , Sumarti Endang ,   Pendidikan Bahasa dan Sastra Indonesia, IKIP Budi Utomo Malang, Indonesia, Sriwulandari Yunita Anas ,   Pendidikan Bahasa dan Sastra Indonesia, IKIP Budi Utomo Malang, Indonesia, Sorraya Artifa ,   Pendidikan Bahasa dan Sastra Indonesia, IKIP Budi Utomo Malang, Indonesia
Published: November 2022

The existence of the novel Gadis Pantai, is a form of a record of Pramoedya Ananta Toer's long journey full of information and factual data derived from in-depth research and experiences deeply rooted in his thinking so that it is interesting to study in the perspective of Michel Foucault's critical discourse. The approach used is a qualitative research approach with Michel Foucault's critical discourse analysis method. The steps taken are to identify to identify then analyzed and concluded. After being analyzed using these approaches and methods, the following results were obtained. First, the relationships of the Gadis Pantai with her parents show hegemonic-exploitative powers. Second, Bendoro's relations with The Gadis Pantai as Mas Nganten are the powers of inequality-exploitative, and meaninglessness. Third, The Gadis Pantai's resistance to Bendoro is a form of open resistance head-to-head due to the emergence of the Gadis Pantai's existential consciousness to fight for her right as a mother even though it ended in vain because the Gadis Pantai was powerless in the face of Bendoro's strong power. However, at least, Gadis Pantai has shown that women are not always the second sex, the other, let alone Mas Nganten, they also have rights and will always fight to determine their own destiny.
Random UV-Mutagenesis of Lactobacillus Species for the Generation of a Mutant with Better Probiotic Potential
Authors:   National Facility for Biopharmaceuticals, Guru Nanak Khalsa College, Mumbai 400019, India, Jha Vikas , Rasal Saloni ,   National Facility for Biopharmaceuticals, Guru Nanak Khalsa College, Mumbai 400019, India, Bhargava Agraj ,   Department of Biology, The Rheinische Friedrich-Wilhelms-Universität Bonn, Jadhav Pallavi ,   Department of Five Years Integrated Course in Bioanalytical Sciences, Guru Nanak Khalsa College, Mumbai, India, Ansari , Rukayya ,   Department of Biotechnology, G. N. Khalsa College, Matunga, Maharashtra, India, Marath Aishwarya ,   Department of Biotechnology, G. N. Khalsa College, Matunga, Maharashtra, India, Jagtap Leena ,   Department of Biological Sciences, SVKM’s NMIMS Sunadan Divatia School of Science, India, Khan Farzha ,   Department of Biological Sciences, SVKM’s NMIMS Sunadan Divatia School of Science, India, Kumar Abhishek ,   National Facility for Biopharmaceuticals, Guru Nanak Khalsa College, Mumbai 400019, India, Saiya Badal ,   Department of Biological Sciences, SVKM’s NMIMS Sunadan Divatia School of Science, India
Published: November 2022

Antibiotic resistance has reduced the value of synthetic drugs, offering up possibilities for the development of new substitutes with significant potential to benefit their host. Probiotics are living microbes that restore the microbiome in the gut. The main purpose of this research is to explore the probiotic potential of Lactic Acid Bacteria and its mutant strains. LAB was isolated from a variety of fermented foods. They were first examined for cultural, microscopic, and biochemical properties. The four probiotic LAB isolates were identified to the strain level using 16S rRNA gene sequence comparisons. The tolerance of these strains to pH, NaCl, and phenol was used to establish their safety. In vitro testing for probiotic potential comprised survival under simulated GI tract conditions and antimicrobial activity. Lastly exposure to U.V. for varied periods for strain improvement. The isolates were screened as Limosilactobacillus fermentum (LAB01), Lactobacillus acidophilus (LAB02), Lactobacillus paracasei (LAB03) and Lactobacillus delbrueckii subsp bulgaricus (LAB04). Mutated strains were resistant to a wide spectrum of antibiotics, whereas most strains were only tolerant to limited antibiotics. The correlation between gut flora and health is exciting since it opens new avenues for research. Based on these findings, it can be concluded that LAB is a potent probiotic
Development ofpedagogical education in theKuban and Adygea in 192
Authors:   Kuban State Technological University, Emtyl Z.Ya. , Vazankov M.V.
Published: November 2022

The article examines the content, forms and results of the development of pedagogical education in the Kuban and Adygea in the 1920s on the basis of a wide range of factual material in the context of solving state problems and developing the local socio-cultural environment. On the basis of the research, the authors have concluded that during the investigated period there was no need to talk about the existence of planning principles and a certain system in its organization. In the course of implementing the guidelines of the central authorities for the training of socialist teachers, real local conditions were not taken into account: the low level of literacy of the population, the lack of the necessary financial, material basis, trained personnel and experience in relevant organizational work. The class selection aimed at its proletarianization had a negative effect on the qualitative level of new teachers. As the main result of the development of teacher education, the acquisition of organizational experience necessary for large-scale planned training of personnel, which has been unfolding since the early 1930s has been noted.
SOME ASPECTS OF DIGITALIZATION IN THE METHODOLOGICAL AND MATHEMATICAL TRAINING OF FUTURE PRIMARY SCHOOL TEACHERS
Authors:   Adygh State University, Evtykhova N.M. , Burkova L.L.
Published: November 2022

The relevance. The need for distance learning during the pandemic and mixed learning has now led to an accelerated study of using various digital resources. Digital transformation has become a part of the educational process. This is evidenced by such documents as Decree of the President of the Russian Federation of July 21, 2020 No. 474 "On the National Development Goals of the Russian Federation for the period up to 2030", which lists the achievement of "digital maturity" of key sectors of the economy and the social sphere as one of the target indicators of the national goal of "digital transformation". As well as by the "Strategy for the Digital Transformation of Science and Higher Education" and the "Passport of the Strategy of "Digital Transformation of Education", published on the websites of the Ministry of Education and Science and the Ministry of Education of the Russian Federation. Mathematical training of future primary school teachers, as well as comprehensive training, is becoming one of the most important tasks of education. The problem of the research is to identify the most effective digital resources and methods of their application in the context of blended teaching Mathematics to future primary school teachers. The purpose of the article is to reflect some aspects that one has to face in the real educational process during the mathematical training of future primary school teachers in the context of the digital transformation of education. The research methods used are analysis of sources and literature on the research topic, observation, generalization of the experience of using digital resources in educational activities The research results and conclusions are as follows, the authors have analyzed and summarized regulatory documents; the use of digital resources in teaching mathematics has been investigated; an option of the use of digital resources presented. The study has showed the need to develop teaching aids on the use of digital resources in the process of mathematical and methodological training of future primary school teachers.
DISTANCE LEARNING AS A PHENOMENON OF MODERN EDUCATION: TEACHERS' OPINION
Authors:   FSBEI HE ", Ivashchenko T.A. ,   Maikop State Technological University", Dvoynikova E.S.
Published: November 2022

Today distance learning, is among the most relevant and promising ways of learning which is implemented using the capabilities of modern telecommunication technologies, the main role belongs to the global Internet. Meanwhile, the first experiences of using electronic educational resources in practice took place in the second half of the 20th century in the USA, Great Britain, France, China, determining an important place for distance learning in a number of additional education. The deterioration of the sanitary and epidemiological situation in 2020 sharply actualized the issues of using distance learning technologies, which is a factor confirming the relevance of the research. The purpose of the research is to present the point of view of the pedagogical community on the problem of distance learning in modern conditions. The research objectives are to reveal the category of "distance learning" and a number of related concepts ("online learning", "E-learning", "electronic information educational environment"); to present the experience of the universities of the Republic of Adygea in the use of educational resources (online platforms) in the practice of distance learning of higher and secondary educational institutions; to conduct a survey of the opinion of the pedagogical community on distance learning. Material and the research methods. The solution of the tasks set was facilitated by the use of scientific research methods: theoretical ones (analysis of the experience of using distance learning technologies in the practice of educational institutions, comparison, analogy method); empirical ones (survey, observation, description). The information and analytical base was made up of information resources of the Internet network. The research results. Distance learning is learning remotely using current educational technologies (Internet services, online learning platforms, cloud technologies, etc.). The following educational resources (online platforms) are actively used in the distance learning of the universities of the Republic of Adygea: Zoom, Skype, Moodle. A pilot study of the opinions of teachers (teachers of universities and colleges) has made it possible to identify certain problems of online learning, including the likelihood of a decrease in the quality of training of students in a distance format, a number of technical equipment problems, an insufficient level of digital literacy of teachers, etc. Key conclusions: the basis of distance learning is information and communication resources of the Internet; the optimal software resources for organizing online learning are Zoom, Skype, Moodle; promising is the solution to the problem of creating a unified digital educational platform that allows developing unified information standards for distance learning.
Urinary tract infections in complicated kidney stones: Can they be correlated with Guy’s stone score?
Authors: Puia Dragos , Radavoi George Daniel , Proca Tudor Marian , Puia Ancuta , Jinga Viorel , Pricop Catalin
Published: November 2022

Objective: To ascertain the existence of a connection between Guy’s stone score and infectious complications after percutaneous nephrolitholapaxy.
Methods: The retrospective cohort, multi-centre study was conducted in the urology departments of Prof Dr Theodor Burghele Clinical Hospital and C.I. Parhon Clinical Hospital, Romania, and included data of patients who underwent percutaneous nephrolitholapaxy from January 1, 2017, to December 31, 2019. Based on urography, the subjects were assigned to four groups, from GSS1 to GSS4, in accordance with the Guy’s stone score classification. The complication rate after percutaneous nephrolitholapaxy was classified using the modified Clavien staging classification. Demographics, preoperative urine cultures, and the rate of complications were and compared. Data was analysed using SPSS 24.
Results: Of the 246 patients, 116(47.2%) were males and 130(52.8%) were females. The overall mean age was 53.06±13.04 years (range: 18-83). The mean Guy’s stone score was 1.82±0.9. The rate of percutaneous nephrolitholapaxy success was 160(65.04%). There were 105(42.68%) patients in GSS1 group, 63(25.60%) in GSS2, 24(9.75%) in GSS3 and 54(21.95%) in GSS4. There were significantly more preoperative positive urine culture in GSS3 and GSS4 groups compared to GSS1 and GSS2 groups (p<0.05). The rates of complications were statistically different among the groups (p=0.019).
Conclusion: Urinary tract infections were found more frequently in patients with higher Guy’s stone scores compared to those with low scores. The Guy’s stone score classification were found to be a useful tool in predicting the immediate success rate of percutaneous nephrolitholapaxy.
Key Words: Kidney, Stones, Infection, PCNL.
Thiamine responsive megaloblastic anaemia complicated with acute Parvovirus infection: a case report
Authors: Khaliq Sehar
Published: November 2022

Thiamine responsive megaloblastic anaemia syndrome also known as Rogers syndrome is a very rare autosomal recessive disorder. The hallmark of the disease is the presence of the classic triad of anaemia, diabetes mellitus, and sensorineural deafness. We report the case of a 14-year-old boy who presented to us with severe megaloblastic anaemia, diabetes mellitus, and sensorineural deafness. The anaemia was further complicated by acute parvovirus infection. He was put on high doses of thiamine (vitamin B1) which led to an improvement.
Key words: Thiamine, Megaloblastic Anaemia, Deafness, Diabetes Mellitus.
Self-assessment of active learning and critical thinking during problem-based learning: an exploratory study
Authors: Kiran Fatima Mehboob Bana  , Muhammad Shahid Shamim  , Zeelaf Shahid
Published: November 2022

Objective: To assess whether problem-based learning enhances students’ perception of their active learning and critical thinking skills with time, and to validate the self-assessment scale regarding active learning and critical thinking in the local context.
Method: The exploratory study was conducted at the Bahria University Dental College, Karachi, from February to September 2020, and comprised dental undergraduates in their first and second years of the academic programme Data was collected using the self-assessment scale on active learning and critical thinking questionnaire which was administered twice after problem-based learning tutorials. Data was analysed using SPSS 23.
Results: There was a significant difference in the mean questionnaire scores of modules 1 and 3 of the first-year batch and modules 4 and 6 of the second-year batch (p=0.001). Cronbach’s alpha value was 0.735 in the first-year cohort and 0.802 in the second-year cohort.
Conclusion: Dental students’ perception of active learning and critical thinking increased with time using problem-based learning as the tool. The self-assessment scale on active learning and critical thinking was also found validated in the local context.
Key Words: Active learning, Critical thinking, Dental undergraduates, Problem-based learning, PBL, Self-assessment.
Relationship between muscular impairment and psychological health with lower extremity functions in patients with transtibial amputation
Authors: Ayesha Aslam  , Harima Shoukat  , Jahan Saira
Published: November 2022

Objectives: To determine the relationship of muscular impairment and psychological health with lower extremity functions in patients with transtibial amputation.
Method: The correlational study was conducted from March to September 2021 at the Fauji Foundation Hospital, Rawalpindi, Pakistan, and comprised male patients with transtibial amputation. Data was collected using the depression anxiety stress scale and the lower extremity functional scale. The correlation of muscular impairment and psychological health with lower extremity functions was determined. Data was analysed using SPSS 21.
Results: There were 85 male patients with a mean age of 53.74+11.30 years. There was weak iliopsoas muscle strength 4.64+0.50 and reduced muscle length of hamstrings 67.00+6.41 on the affected side. There was non-significant correlation in muscle atrophy of both amputated limb (p=0.82) and non-amputated limb (p=0.58) with lower extremity function. Significant inverse correlation was present between depression, anxiety and stress (p=0.001) with lower extremity function.
Conclusion: Weak iliopsoas muscle strength and tight hamstrings were observed on the amputated side. Muscle atrophy was more in non-amputated limb than amputated limb. There was significant inverse correlation of depression, anxiety and stress with lower extremity function.
Key Words: Anxiety, Depression, Muscle atrophy, Muscle length, Muscle strength, Stress.
COVID-19 and potential aggravation of antimicrobial resistance in Pakistan
Authors: Syed Muhammad Haaris  , Hassan Ahmed  , Syed Mohammad Sarosh
Published: November 2022

Dear Editor,
The ongoing Coronavirus disease 2019 (COVID-19) pandemic has affected a sizable portion of the global population, with over 410 million cases reported globally as of January 15, 20221. Pakistan has had its fair share of these cases, with over 1.4 million people testing positive for COVID as of the date mentioned above1. Antiviral drugs (remdesivir with or without baricitinib), steroids (dexamethasone), immunosuppressants (tocilizumab), monoclonal antibodies (casirivimab and imdevimab), and convalescent plasma have all been used to treat infected people2. Although antibiotics are not recommended for viral infections, they have been overprescribed in COVID patients2.
Pakistan is the world’s third- largest consumer of antibiotics among lower-middle income countries3. With antimicrobial resistance (AMR) already looming as a national concern4 and a history of the emergence of multiple antibiotic- resistant bugs5. One can safely assume that the use of antibiotics has likely escalated amidst the incessant COVID-19 pandemic in Pakistan. A study revealed non-evidence-based antimicrobials among patients with the COVID-19 admitted into Pakistani hospitals, prescription of antibiotics without established bacterial co-infections and an increased consumption of antibiotics such as azithromycin and ciprofloxacin in COVID patients6. This lends credence to our previously stated assumption.
The alarming upsurge in the prescription of antibiotics since the advent of the COVID-19 pandemic is bound to exacerbate the already rampant AMR in Pakistan and rest of the world alike. Several factors contribute to this predicament, including delays in diagnosis, inappropriate drug regimens, poor follow-up, lack of social support for high risk populations and now, due to COVID-19 pandemic, disruption in healthcare services, drug shortages, widespread use of biocides, misuse of antiobiotics and surge in misinformation4.
It is estimated that drug resistant infections kill more than 700,000 people worldwide each year, which likely to rise if the threat is not addressed4. Low- and middle-income countries (LMICs) like Pakistan are likely to suffer the worst consequences of AMR. In light of the potential aggravation of AMR stemming from antibiotic overuse in COVID patients, it is critical for regulating authorities to ensure that antimicrobial stewardship measures are followed when prescribing antibiotics and that non-evidence-based use is avoided. Since AMR is here to stay, the best thing that can be done in this pandemic is to prevent another bug from joining the notorious family of drug-resistant microorganisms.
Arterial blood gas analysis aids early differential diagnosis and treatment of primary and secondary hypokalaemic periodic paralysis
Authors: Xiao-yun Huang  , Wen-jin Fu  , Zhi-zhong Mei  , Chun-fa Jiang  , Han Lin  , Xin-yi Leng
Published: November 2022

This study aimed to examine changes in electrolytes and acid-base status in primary and secondary hypokalaemic periodic paralysis (HypoPP), which will help early differential diagnosis of HypoPP. A total of 64 HypoPP patients were enrolled and relevant data from clinical records was collected. Overall, 64 patients (mean age 28.2±7.3 years) of which 58(91%) were males, with 39, 11 and 14 patients, respectively, diagnosed as primary HypoPP, thyrotoxic HypoPP, and other secondary HypoPPs at discharge, were assessed. Those with HypoPP secondary to conditions other than hyperthyroidism were more likely to develop acid-base imbalance (p<0.001); they had higher pH (p=0.046) and HCO3 levels (p=0.014) at baseline, and needed a higher dose of potassium supplement before the serum potassium level returned to normal (p=0.007) and a longer time to regain full muscle strength (p=0.004), compared with those with primary or thyrotoxic HypoPP. Emergent arterial blood gas analysis may aid early differential diagnosis of patients with primary and secondary HypoPP.
Keywords: Hypokalaemic periodic paralysis, arterial blood gas, acid-base balance
Production and characterization of heat retardant fiber-reinforced geopolymer plates
Authors: GEZER Türkan , AKARKEN Gürkan , CENGİZ Uğur
Published: November 2022

This paper presents an alternative environment-friendly thermal insulation material for the construction industry. We aimed to produce this building material with superior heat resistance properties and comparable strength to the concrete produced with Ordinary Portland Cement. The primary purpose of the experimental studies is to produce a basic geopolymeric plate and to add cellubor and polypropylene fibers to the geopolymeric mortar. In the next stage, fiber-reinforced plates were prepared, thermal experiments were carried out, and discussions and conclusions were formed according to the results and findings. This study initially produced different types of fiber-based metakaolin plates with high heat resistance. Then, the flame test examined the heat resistance of the composite plates formed by the mixture of fibers consisting of cellubor, polypropylene, and cellubor + polypropylene fiber mixtures into geopolymeric mortars. It was found that the metakaolin plates containing approximately 6% by weight of Cellubor in the structure, besides their serious resistance to flame, their heat retardancy properties gave 72% better results than Kalekim (cementitious ceramic tile adhesive) plates and 55% better results than non-fiber metakaolin plates.
EDITORIAL : The how and why of scientific naming: What’s in a name?
Authors: Engel Michael S.
Published: November 2022

Quite a lot, actually. Names organize and give meaning to our world. They give us identity and allow us to communicate clearly and efficiently. In the context of scientific names for living and fossil organisms, they link data from around the globe into a synthetic framework from which we can make powerful predictions and effective strategies: everything from governmental policies and next-generation medicines to the origins of diversity and its responses to climate change. These, and many other reasons, are the why, but how is equally important. Unlike folk taxonomies, which are rich in cultural tradition and applicable only at local scales, scientific nomenclature must abide specific rules to remain effective globally, unbounded by the vagaries of local customs. These names must also transcend time so that data from past and future generations can be meaningfully synergized for their greatest benefit. Not surprisingly, to achieve such lofty goals, an entire form of information science is needed, one complete with its own terminology and pragmatic rules. The how of scientific naming is as vital as the why, for to fail at the first means catastrophe for the fundamental reasons of the latter. Imagine bad practices for the scientific naming of drugs or diseases and the tsunami of disastrous impacts that would follow. Now imagine the same if we failed at communicating about disease-transmitting mosquitos or poisonous mushrooms. Scientific names have life-sustaining importance and we cannot be cavalier about taxonomic science and formalized nomenclature.