bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria.
Authors: Juhlin L , Rihoux J P
Published: July 2023

The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria. Cetirizine markedly reduced the weal and flare induced by all these agents as measured 12 min after the injections. The delayed reactions observed after injection of PAF, kallikrein and serum were also inhibited by cetirizine at 6 hours. In addition, reactions which were present 20 h after injection of the agent before administration of cetirizine were found to be inhibited at the same point in time after cetirizine treatment. These effects might explain the good inhibitory clinical effect of cetirizine on the patients' urticaria. No side-effects were noted during the treatment.
Adult T cell leukemia accompanied by annular elastolytic giant cell granuloma.
Authors: Kuramoto Y , Watanabe M , Tagami H
Published: July 2023

We report a 74-year-old Japanese patient with adult T-cell leukemia who concurrently developed annular elastolytic giant cell granuloma. Initially, itchy granulomatous lesions developed on his face, nape of the neck and dorsa of the hands, but gradually erythematous plaques appeared on the back and lower limbs. The histology of the granulomatous lesions revealed coexistence of an epithelioid cell granuloma with giant cells that phagocytosed elastic fibres in the dermis and Pautrier's microabscesses in the overlying epidermis. Subsequent sequential histological studies of an erythematous plaque revealed the development of granulomatous changes in pre-existing lymphomatous lesions. Laboratory data revealed the presence of antibody to human T cell leukemia/lymphoma virus I and 14,200 white cells/mm3 in the peripheral blood with 2% atypical lymphocytes which eventually amounted to 30%, one month before his death.
The effect of ketoconazole and itraconazole on the filamentous form of Pityrosporum ovale.
Authors: Faergemann J , Borgers M
Published: July 2023

The effect of ketoconazole and itraconazole on the filamentous form of Pityrosporum ovale in vitro was studied. In a recently developed model, using human stratum corneum in vitro, P. ovale transformed into the filamentous form in 25-30% of the cells. Ketoconazole and itraconazole in concentrations of 0.01, 0.1 and 1 microgram/ml were incubated together with P. ovale cells on human stratum corneum pieces placed on a lipid-enriched culture medium. Both agents effectively blocked the production of hyphae. From the low concentration onwards, the changes consisted of a diminishing transformation into hyphae. With transmission electron microscopy, the interior of many cells was often in an advanced stage of necrosis. Exposure to 1 microgram/ml itraconazole causes a disorganization of the internal organelles in 83% of the cells. This model for the production of hyphae of P. ovale in vitro proved very valuable in screening the activity of antimycotic agents against the filamentous form of this yeast.
Contraction phenomenon of type I collagen gel by melanoma cells.
Authors: Kono T , Furukawa M , Tanii T , Kitajima J , Mizuno N , Ishii M , Hamada T
Published: July 2023

In order to study the interaction between melanoma cells and collagen, B16 murine melanoma cells were embedded and cultured in type I collagen gel. Melanoma cells cultured in the collagen gel became elongated, as compared with those cultured on plastic, and some of them assumed a dendritic form. The gel contracted very slowly but steadily during culturing of melanoma cells, as in the experiment using fibroblasts. On the 20th day of culture the area of the gel accounted for only 32% of that when culture started. This contraction was enhanced by retinoic acid, which is known to induce cell differentiation. The contractility of the gel differed between various lines of melanoma cells. The present observations raise the possibility of interaction between melanoma cells and type I collagen.
Simultaneous occurrence of calcification and amyloid deposit in pilomatricoma.
Authors: Sano Y , Mihara M , Miyamoto T , Shimao S
Published: July 2023

Amyloid deposition was encountered in 10 of 16 samples of pilomatricoma, indicating that the deposition of amyloid is nearly as common as calcification in pilomatricoma. In addition, a simultaneous occurrence of calcification and amyloid deposit in pilomatricoma was recognized in 9 of 16 samples. The calcification and the deposition of amyloid developed topographically in the same area within the shadow cell masses. Such an area was revealed as moderately basophilic, amorphous, or hyalinized by H&E staining. Electron microscopy revealed spotty calcium deposits in amyloid. No light chains of human immunoglobulin were detected in the amyloid-deposited area. Amyloid in this tumour may facilitate calcification or serve as a matrix for subsequent calcification.
Intradermal antigen tests in psoriasis.
Authors: McFadden J P , Powles A V , Baker B S , Valdimarsson H , Fry L
Published: July 2023

To assess whether elicitation of delayed hypersensitivity may be superior to trauma in inducing the Koebner reaction in psoriasis, 12 affected patients and 9 control subjects were tested with 0.1 ml intradermal injections of streptokinase/streptodornase (20 mu/5 mu per 0.1 ml), PPD (1 in 1000) and saline control solutions in a double-blind study; Koebner status was also established in the psoriatic patients. Injected sites were examined at 48 h and 7, 14, 21 and 28 days for local development of psoriasis, erythema and induration (diameter). One patient was Koebner-positive and developed psoriasis at all three injection sites. The other, Koebner-negative psoriatic subjects did not develop psoriasis locally. However, compared with non-psoriatic controls they showed a marked delay in resolution of the delayed hypersensitivity reaction to the PPD antigen and a similar but less marked phenomenon was observed for streptokinase/streptodornase. These findings indicate that intradermal antigen, of the nature and amount used in this study, is no more effective in inducing the Koebner phenomenon than injury alone. However, the ability of psoriasis patients to switch off cell-mediated immune reaction appears to be impaired.
Serum-soluble interleukin 2 receptor in psoriasis. Failure to reflect clinical improvement.
Authors: Kemmett D , Symons J A , Colver G B , Duff G W
Published: July 2023

Interleukin 2 (IL-2) is a T-cell growth factor produced by activated T cells. The cellular receptor for IL-2 is also expressed on activated T cells and one of its component molecules can be shed from the cell and measured as a soluble protein (sIL-2R). Blood levels of sIL-2R can be used to monitor in vivo immune activation and have been shown to correlate with clinical disease activity in conditions such as rheumatoid arthritis and atopic eczema. The present study shows that serum sIL-2R levels are raised in patients with chronic plaque psoriasis. These elevated serum levels were maintained during successful treatment of the skin lesions with topical tar preparations. This is in contrast to atopic eczema where serum sIL-2R levels fall with treatment and may indicate that topical treatment of psoriasis does not correct the underlying state of immune activation, even when resolution of the skin plaques is achieved.
Roxithromycin and erythromycin in chlamydia-negative non-gonococcal urethritis.
Authors: Worm A M
Published: July 2023

The clinical efficacy and safety of roxithromycin 300 mg once a day was compared with that of erythromycin 500 mg twice a day in 87 men with chlamydia-negative non-gonococcal urethritis. In the roxithromycin group the clinical efficacy rate was 88% on day 8 and between 78% and 84% on day 21. In the erythromycin group the clinical efficacy rate was 98% on day 8 and 86% on day 21, a non-significant difference. Side effects were mainly gastrointestinal, occurring in about 15% of patients receiving each treatment.
Patients with dermatitis herpetiformis, acne, psoriasis and Darier's disease have low epidermal zinc concentrations.
Authors: Michaëlsson G , Ljunghall K
Published: July 2023

Zinc concentration was determined in epidermis, papillary dermis and serum in patients with dermatitis herpetiformis, acne or psoriasis and in two small groups of patients with ichthyosis vulgaris and Darier's disease. Except in ichthyosis vulgaris the zinc level in epidermis was decreased in all these disorders. The mean serum zinc concentration was, however, significantly decreased only in men with dermatitis herpetiformis. There was no correlation between the concentration of zinc in epidermis or dermis and that in serum. The decreased epidermal zinc concentration indicates that many of the patients have a zinc deficiency in spite of a "normal" serum zinc value. Supplementation of zinc might therefore be of value in patients with these disorders.
Epidemiology of genital herpes infections in Sweden.
Authors: Löwhagen G B , Jansen E , Nordenfelt E , Lycke E
Published: July 2023

The epidemiological pattern of genital herpes infections was studied by evaluating virus isolations and serological results based on samples collected from Göteborg and Malmö, the two largest urban areas of southern Sweden. 1087 strains of herpes simplex virus isolated from cases of clinical herpes in Göteborg during the period 1980 to 1987 were evaluated for type relatedness. It was found that type 1 constituted 10% of the overall number of strains isolated with insignificant variation from year to year and type 1 and 2 occurred in same proportions in men and women. The HSV type 2 specific seroprevalence in 1158 pregnant women from Malmö during the years 1973, 1979, 1987 and 1989 was studied. A significant increase in prevalence figures was noted from 1973 to 1987. The age-related seroprevalence of 1211 men and 531 women in Göteborg suggested a 5 to 10% increase per 5-year period. Generally, higher prevalence was observed in women than in men, and about 10% of the men and 20% of the women might have been asymptomatically infected.
5-S-cysteinyldopac in human urine.
Authors: Carstam R , Brinck C , Fornstedt B , Rorsman H , Rosengren E
Published: July 2023

5-S-Cysteinyldopac, a compound hitherto demonstrated only in brain tissue, has been isolated and quantified in urine. The urines from 12 individuals were found to contain 20 +/- 9.1 micrograms 5-S-cysteinyldopac/24 hours. Incubation of 5-S-cysteinyldopamine with MAO-containing tissue did not give any formation of 5-S-cysteinyldopac, indicating that this compound is formed by nucleophilic addition of cysteine directly to dopac. The findings give further evidence for a small but significant non-specific oxidation of endogenous catechol derivatives in vivo, a fact to be considered when using 5-S-cysteinyldopa as a measure of pigment metabolism.
Alternative therapy for atopic dermatitis and psoriasis: patient-reported motivation, information source and effect.
Authors: Jensen P
Published: July 2023

In a questionnaire study, 227 patients with atopic dermatitis and 215 with psoriasis, who had used alternative medicine, were asked to state their main reason for trying alternative medicine. The answers indicated that the absence of satisfactory effect of physician-provided therapy was the most decisive factor. Their main information sources on alternative therapies were persons without skin disease, and the mass media. The majority reported no improvement, or even aggravation of their skin disease, as a result of alternative treatments (except for diet changes). These findings emphasize the need for documentation of effect of alternative medicine, as well as for further research and education efforts in order to improve therapy for atopic dermatitis and psoriasis.
The effect of clobetasol-17-propionate and crude coal tar on dithranol-induced inflammation. A clinical and biochemical study.
Authors: Van de Kerkhof P C , Timmerman M G
Published: July 2023

Clobetasol-17-propionate (CP) and crude coal tar (CT) have an anti-inflammatory potential. Both agents have been advocated to suppress irritation of the skin during dithranol treatment. The effect of CP and CT on dithranol-induced irritation was studied by the assessment of erythema and measurement of alkaline phosphatase (ALP) as a direct reflection of the metabolic activity of the endothelial cells. Dithranol was applied for 2 h in the relatively high concentration of 10%, which resulted in a marked inflammation of the skin in all volunteers. Neither CP nor CT influenced the erythema. In contrast, CP and CT had a synergistic effect on the dithranol-induced induction of ALP. In conclusion, the present study indicates that CP and CT are not indicated for the treatment of dithranol-induced irritation.
Exchange of dominant lymphoid cell clones in a patient with adult T-cell leukemia/lymphoma.
Authors: Iwatsuki K , Inoue F , Takigawa M , Iemoto G , Nagatani T , Nakajima H , Yamada M
Published: July 2023

We performed a genotypic study on lymphoid cells from a patient with adult T-cell leukemia (ATL). Clonal proliferation of human lymphotropic virus type-1(HTLV-1)-infected helper T-cells was detected in the primary skin tumors, while no clonality of the virus-infected lymphocytes was observed in the peripheral blood. Following intensive chemotherapy, however, we detected the presence of two genotypically different HTLV-1-infected lymphocyte clones in different samples taken from the peripheral blood. These data demonstrated the exchange of the dominant neoplastic clone in the clinical course of ATL, suggesting the possibility that a certain clone among many repertoires of HTLV-1-infected T-cells has a capability of leukemogenesis, instead of the primary tumour cells.
Oral cyclosporin A is effective in clearing persistent pustulosis palmaris et plantaris.
Authors: Meinardi M M , De Rie M A , Bos J D
Published: July 2023

In a prospective open study, seven patients with persistent pustulosis palmaris et plantaris were treated with oral Cyclosporin A (CsA). Clinical efficacy was assessed on a semi-quantitative 0-4 point scale for erythema, desquamation, induration and pustulation. CsA controlled skin lesions in doses ranging from 1.1 to 6.1 mg/kg body weight/day. Clinical side effects included renal impairment, nausea and tiredness. Rapid recurrence of the skin lesions was observed on withdrawal or insufficient treatment with the drug.
Decreased concentration of selenium in whole blood and plasma in acne vulgaris
Authors: Michaëlsson G
Published: July 2023

No abstract available.
Immunohistopathology of light-induced skin lesions in lupus erythematosus.
Authors: Velthuis P J , Van Weelden H , Van Wichen D , Baart de la Faille H
Published: July 2023

Recently we have been able to induce pathological skin reactions with UVB, UVA and visible light in patients with lupus erythematosus (LE). The pathological skin reactions had the appearance of spontaneously developed LE lesions. In the present study, using patients with polymorphic light eruption as controls, we subsequently investigated what types of immunohistochemical abnormalities were found in these lesions. It was shown that in the induced skin lesions, phenotypically similar inflammatory cells were found as in spontaneously evolved lesions. Granular deposits of immunoreactants, as found in most spontaneously evolved LE lesions, occurred in 12 out of 16 LE patients 7-10 days after onset of the artificial irradiation. The dermal infiltrates in light-induced LE lesions differed mainly from those in polymorphic light eruption, by the amounts of CD1+ cells (Langerhans' cells). In polymorphic light eruption, the relatively large amount of these cells suggests an active migration of antigen-presenting cells, a mechanism apparently not operative in LE. Our results underline the importance of the pathogenic action of light in LE.
Home-based telerehabilitation for community-dwelling persons with stroke during the COVID-19 pandemic: A pilot study
Authors: Leochico Carl Froilan D. , Austria Edgardo Miguel V. , Gelisanga Maribeth Anne P. , Ignacio Sharon D. , Mojica Jose Alvin P.
Published: July 2023

Objectives: To determine the feasibility and safety of use of asynchronous telerehabilitation for community-dwelling persons with stroke in the Philippines during the COVID-19 (SARS-CoV-2) pandemic, and to evaluate the change in participants’ telerehabilitation perceptions, physical activity, and well-being after a 2-week home-based telerehabilitation programme using a common social media application.Design: Pilot study.Participants: Nineteen ambulatory, non-aphasic adult members of a national university hospital stroke support group in the Philippines.Methods: Pre-participation screening was performed using the Physical Activity Readiness Questionnaire. The participants were medically cleared prior to study enrollment. They then engaged in telerehabilitation by watching original easy-to-follow home exercise videos prepared and posted by the study authors on a private group page on Facebook™ every other day for 2 weeks. Descriptive statistics was performed. Results: All 19 participants (mean age: 54.9 years) completed the programme with no significant adverse events. The majority of subjects improved their telerehabilitation perceptions (based on the Telepractice Questionnaire), physical activity levels (based on the Simple Physical Activity Questionnaire), and perceived well-being (based on the Happiness Scale).Conclusion: Asynchronous telerehabilitation using a common low-cost social media application is feasible and safe for community-dwelling persons with chronic stroke in a lower-middle-income country.
LAY ABSTRACTThe COVID-19 (SARS-CoV-2) pandemic led us to find alternative ways to connect patients and healthcare providers despite physical distance. For instance, telerehabilitation via available telecommunication technologies can be used to provide consultation and therapy services to persons living with disability. In resource-limited countries, such as the Philippines, telerehabilitation was not widely practiced prior to the pandemic, due to several factors, such as lack of acceptance and high costs. This pilot study demonstrates the feasibility, effectiveness, and safety of telerehabilitation using a common low-cost social media application for patients with chronic stroke. Nineteen adult members of a stroke support group safely completed a 2-week telerehabilitation programme by watching original easy-to-follow home exercise videos posted on a private group page on Facebook™. The majority of subjects had positive experiences with the programme, and had improved perceptions of telerehabilitation, physical activity levels, and perceived well-being after 2 weeks.
Features of Volume Sphygmography Parameters in Men Working under the Influence of Industrial Noise
Authors:   Nizhny Novgorod Research Institute of Hygiene and Occupational Pathology of Rospotrebnadzor, Rudoy Mariya D. , Makarova Ekaterina V. ,   Nizhny Novgorod Research Institute of Hygiene and Occupational Pathology of Rospotrebnadzor,   Privolzhsky Research Medical University of the Ministry of Health of Russia
Published: July 2023

INTRODUCTION: Noise is one of the most common hazardous physical factors that a person is exposed to at the workplace. It is important to study changes in the cardiovascular system induced by exposure to industrial noise. AIM: To evaluate the effect of industrial noise on the parameters of volume sphygmography in men of working age. MATERIALS AND METHODS: The study included 205 men of the working age undergoing periodic medical examinations at the polyclinic of the Nizhny Novgorod Research Institute of Hygiene and Occupational Pathology of Rospotrebnadzor. Two groups of the subjects were identified: the main group (150 people) — working under the influence of industrial noise exceeding the maximum permissible level, and the comparison group (55 people) — working out of contact with hazardous industrial factors. To assess the stiffness of the vascular wall, all patients underwent volume sphygmography on VaSera VS-1500N device (FukudaDenshi, Japan). RESULTS: The formed groups were comparable in the main cardiovascular risk factors. However, of attention was the trend towards an increase in the share of smoking patients in the control group. The analysis of the parameters. of volume sphygmography showed a statistically significant increase in the stiffness index of the vascular wall on the right and left, in the estimated age of the arteries and also frequent (7.5 times) detection of syndrome of early vascular aging in the main group. CONCLUSION: The identified deviations of sphygmography parameters are a marker of early changes in the vascular wall in people working with noise. It is advisable that an in-depth study of the state of the cardiovascular system be conducted including assessment of vascular rigidity, in persons exposed to this industrial factor.
Alopecia Areata a Classic Vitiligo Comorbidity
Authors:   Society of Integrative Dermatology, Saranyuk Roman V. ,   Center for Medical Examinations and Prevention, Gosteva Tat’yana A. ,   Society of Integrative Dermatology,   Center for Medical Examinations and Prevention, Agafonova Elena V. ,   Dushanbe City Clinical Hospital of Skin Diseases
Published: July 2023

INTRODUCTION: Vitiligo is an acquired autoimmune skin disease clinically manifested by foci of depigmentation due to the death of epidermal melanocytes. Although vitiligo most often runs in isolation, being limited to a pathological process in skin, this disease can lead to the development of a number of comorbid disorders. Alopecia areata also being an autoimmune disorder of skin appendages, is one of the most common comorbid disorders in vitiligo, manifesting along with the main disease, against the background main disease, or as the main disease itself. In the article, a clinical case of association of vitiligo and alopecia areata is presented, similarities and differences in their pathogenesis are discussed, and other comorbid disorders are described. CONCLUSION: Determination and identification of comorbid disorders with the underlying chronic dermatosis is an important task aiming to prevent the development of probable autoimmune and autoinflammatory disorders. Despite the fact that vitiligo usually runs without systemic manifestations, identification and prevention of a comorbid pathology of the dermatosis should not be ignored by clinicians of different profiles.
Expression Microarrays: Possibilities of Application in Clinical Oncology
Authors:   Ryazan State Medical University, Kulikov Evgeniy P. , Mertsalov Sergey A. ,   Ryazan State Medical University, Shumskaya Evgeniya I. ,   Ryazan State Medical University, Piskunov Roman O. ,   Ryazan State Medical University
Published: July 2023

INTRODUCTION: Molecular oncology is currently undergoing a fairly rapid development due to the emergence of new technologies and modernization of already known methods. These technologies allow not only to update and clarify the understanding of the molecular genetic nature of tumors, but also to develop new directions for the therapy and the course of cancer diseases. The prerequisite for this scientific direction was the decoding of the human genome, as a result of which most human genes have been identified and mapped by now. Microarray technology has been since the late 1980s and has been rapidly developing since then. In a short time, biological microarrays have evolved into an independent field of analysis, including both the study of fundamental problems of molecular biology and molecular evolution, and practical applications in medicine, pharmacology, forensic expertise. AIM: To demonstrate the potential of the microarray expression assay method in clinical oncology, to describe the history of elaboration, evolution, the principle of the method and possibilities of application of expression microarrays at the current stage of clinical oncology development. MATERIALS AND METHODS: The study was carried out at Ryazan State Medical University. The review included sources found in PubMed, Google Scholar, and eLibrary using the query ‘expression microarrays’ and ‘molecular genetic technologies in oncology’. A total, of 126,455 results were found for the query ‘expression microarrays’ in PubMed and Google Scholar. Thirty-five articles were selected, after a relativity analysis of the sources. A total, of 613 results were found in the eLibrary system for the query ‘molecular genetic technology in oncology’, and 15 articles were selected. Thus, 49 articles were included in the final version. CONCLUSION: The advent of microarray technology marked a new stage in molecular genetic analysis. This method allows simultaneous analysis of hundreds of transcription products and even the entire transcriptome, which together with the data on functions of tumor proteins already opens wide horizons for the use of this technology in clinic. Accumulated data allow to see a wide perspective in this method in terms of analysis of expression profile, metastatic potential of tumors, differential diagnosis between different types of malignant neoplasia, and thus individualize the treatment approach for each individual patient. In our opinion, expression profile analysis is an area promising for further, even more detailed study and discussion within the framework of clinical oncology.
Role of Stromal Cells in Angiogenesis of Skin Wounds: Review
Authors:   Ryazan State Medical University, Cherdantseva Tat’yana M. , Nekrasova Marina S. ,   Ryazan State Medical University, Kachkurkina Antonina A. ,   Ryazan State Medical University, Enenkov Nikita V. ,   Ryazan State Medical University, Chukhanov Mikhail S. ,   Altay State Medical University
Published: July 2023

INTRODUCTION: The study of skin wound regeneration has not lost its relevance, especially among surgeons. Angiogenesis is a key factor in wound healing. It is known that the optimal blood supply provides the tissue with nutrients, growth factors, immune cells necessary for the complete repair of skin defect. Insufficient ability to restore functional blood supply to the wound area can lead to chronic non-healing wounds. Therefore, the identification and validation of various factors influencing angiogenesis in the wound bed is of great interest for the development of potential therapeutic agents. The aim of this review is to highlight the current understanding of the mechanisms and morphological manifestations of skin wound angiogenesis, as well as the functional significance of stromal cells involved in this process. The contribution of macrophages, pericytes, mast cells, telocytes to the mechanisms of formation of microcirculatory vessels is shown. The search for literary sources was carried out in the electronic systems eLIBRARY.RU and PubMed by the main keywords of the topic: histology, skin wound regeneration, angiogenesis, stromal cells, macrophages, mast cells, pericytes, telocytes. The publications were analyzed over the last 12 years. The criteria for including a research in the review were the simultaneous mention of several keywords in the article. CONCLUSION: Analysis of the literature demonstrates the relevance of the study of angiogenesis. Modern morphological methods permitted to describe complex intercellular interactions providing the growth of the vascular network. Despite the large number of studies in this area, morphological data are constantly being supplemented to expand the potentials of histological and immunohistochemical studies. Cellular interactions during wound healing are being actively studied and confirmed to be used in the study of the mechanisms of action of drugs and in the development of new methods for treating wounds of various origin. This is of great importance, for example, in search for new reconstructive technologies, for creation of blood vessel grafts, and for development of endothelial prostheses based on non-degradable synthetic materials.
Orthopedic Rehabilitation by Dental Implantation in Public Healthcare System
Authors:   Ryazan State Medical University, Peshkov Mikhail V. ,   Dental Polyclinic No. 1, Tishkina Larisa N. ,   Ryazan State Medical University,   Dental Polyclinic No. 1, Uspenskaya Irina V. ,   Ryazan State Medical University
Published: July 2023

INTRODUCTION: New modern technology – rehabilitation of missing teeth by dental implantation is relevant nowadays, since it determines the high result of orthopedic rehabilitation and improves the quality of patients’ life. The work presents the aspects of the implantological treatment in the system of public healthcare of the Ryazan region. The article, on an example of the united city dental organization providing dental services to the entire population of the regional center, presents difficulties in identifying the real need for dental implantation at the regional level, which is associated with the fact of receiving dental care by a part of patients in private clinics that do not submit statistical data to the reports of the region. The data of a scientific study conducted in the Ryazan region to identify the loyalty of old-age pensioners to public dental organizations are presented. The influence of preventive measures aimed at combating the pandemic of the new coronavirus infection (COVID-19) on the implementation of the volumes of dental care, including dental implantation, is noted. CONCLUSION: The development of the method of orthopedic rehabilitation using dental implantation in the public healthcare system is an important method of rehabilitation of patients with partial and complete loss of teeth, including a socially unprotected group of people of non-working age – pensioners by age who are loyal mainly to public dental organizations.
Pengenalan Pendidikan Seni Tari Pada Anak Taman Kanak-Kanak
Authors: Astuti Fuji
Published: July 2023

The limitations of kindergarten teachers, who generally do not have an art education background, are not a barrier to not teaching dance to kindergarten children, because learning the art of dance in kindergarten children is prioritized on how teachers can motivate students to be able to carry out locomotor movements with confidence that can be done while playing. Based on the results of the training provided to kindergarten teachers throughout the district. Pasaman Barat is able to organize simple dances and can be taught to kindergarten children according to the level of difficulty and characteristics of kindergarten children. In this training, teachers are trained to explore and imitate movements according to the level of understanding and abilities of kindergarten children as objects that are used as a source of expression for expressive movements for students. The technique used during the training is the group method. In each group, the teacher identifies the characteristic tendencies of the students, which then after getting the ideas, then the ideas and ideas are developed in a theme as the basis for constructing a series of dance moves so that they become a dance repertoire that is ready to be taught to kindergarten children. Thus the dance that is taught to kindergarten children can be done by class teachers even though they do not have a background in dance education. The dance that is taught can be felt by students, because the material provided is adjusted to the level of difficulty and characteristics of the child. Furthermore, dance learning in kindergarten children is more aimed at exploring the potential that exists in children through the process of exploration and imitation so as to give birth to expressive movements according to the level of understanding carried out while playing in a pleasant atmosphere.
Perbedaan Hasil Belajar Seni Tari Menggunakan Multimedia Interaktif Dengan Media Konvensional Pada Siswa Di SMP N 1 Talamau
Authors: Hanifa Isra , Astuti Fuji
Published: July 2023

Penelitianainiabertujuan untuk mengetahui perbandingan hasil belajar menggunakan multimedia interaktif dengan media konvensional pada siswa kelas VIII SMP N 1 Talamau. Jenis PeneIitian ini adalah peneIitianakuantitatif. PopulasiApenelitianAini adalah seluruh siswa kelas VIII SMP N 1 Talamau. Sampel dari penelitian terdiri dari dua kelas, yaitu kelas eksperimen (VIII 3A) dan kelas kontrol (VIII 2B) ditentukan dengan cara representative (mewakili). Data dikumpulkan dengan menggunakan tes (soal objektif). Sebelum data di analisis terlebih dahulu dilakukanauji persyaratanaanalisis data berupa uji normaIitas dan uji homogenitas. HasiI peneIitian menyatakan bahwa terdapat perbedaan yang  signifikan  dalam penggunaan multimedia interaktif terhadap  hasil  belajar  seni budaya siswa kelas VIII SMP N 1 Talamau dengan nilai thitung > ttabel (1,86>1,67). Dengan kata Iain penggunaan multimedia interaktif  berpengaruh terhadap hasiI beIajar seni budaya siswa keIas VIII SMP N 1 Talamau. Demikian juga haInya dapat dibuktikan dengan perbedaan hasil nilai rata-rata siswa kelas VIII SMP N 1 Talamau menggunakan multimedia interaktif dengan media konvensional dengan niIai rata-rata kelas eksperimen 81,43 dan kelas kontroI 74,64.  Untuk itu agar hasiI belajar seni budaya  Iebih baik, makaApenggunaan multimedia interaktif harus ditingkatkan.
Characterization of the physical and ruminal activities related to estrus in dairy cows raised on Chinese commercial farms
Authors:   Department of Information and Computing Science, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province, China, Zhou Xiaojing , Xu Chuang , Gomes Lopes Matheus , Loor Juan J , Shao Yunhong , Jia Bin , Shao Guang , Huang Baoyin
Published: July 2023

This study aimed to describe the estrus-related changes in dairy cattle in parameters automatically recorded through an HR-Tag (SCR Engineers Ltd., Netanya, Israel) or a neck collar (Nedap Livestock Management, Groenlo, Netherlands). On two commercial dairy farms, the baseline period was defined as the mean of 3 d before and 3 d after estrus day. In the HR-Tag monitored herd, changes in physical activity and behavioral parameters (lying bouts, lying duration, total lying time, lying ratio) were studied in 78 estrous cycles. The cows were classified in groups according to parity (primiparous, n = 34; and multiparous, n = 44), milk production (MK1, n = 7, > 47 kg/d; MK2, n = 12, 42-47 kg/d; MK3, n = 43, 31-42 kg/d; and MK4, n = 16, < 31 kg/d) and lactation stage (DIM1, n = 34, ≤ 60 d; DIM2, n = 22, 61-120 d; and DIM3, n = 22, ≥ 121 d). In the neck-collar monitored herd, we investigated physical activity on estrus day and total daily feeding time, rumination time and inactivity time in 35 dairy cows during the peri-estrus period. On estrus day, the effects of parity and milk production on physical activity, and the differences in total daily feeding time, rumination time and inactivity time between estrus day and the baseline period were evaluated. The cows were classified in groups according to parity (primiparous, n = 9; and multiparous, n = 26), and milk production (MK1, n = 5, > 41 kg/d; MK2, n = 17, 32-41 kg/d; and MK3, n = 13, < 32 kg/d). ANOVA was performed to determine differences in the continuous data, and comparing means was performed to estimate differences within and between groups, using SPSS 23.0. Ordinal logistic regression was adopted to analyze the factors affecting physical activity on estrus day. Results from the HR-Tag monitored herd demonstrated that on estrus day, physical activity increased compared with the baseline period, and average number lying bouts on estrus day was markedly lower than at baseline, as well as total lying time and lying ratio, with values of -3.53 ± 0.55, -188.02 ± 21.46 and -14.05 ± 1.37, respectively. For the neck collar-monitored herd, when the TFT (total feeding time) of MK2 cows increased by one unit, physical activity was 3.19 times (P=0.03) more likely to increase by one unit compared to those without increased TFT. Overall, our data underscored the important physical, behavioral and ruminal changes related to estrus, which were accurately detected through the automated monitoring systems. Thus, it is suggested that HR-Tags and neck collars are suitable tools for estrus detection in commercial dairy herds.
Analysis of factors influencing the academic education of future bachelors in Electronics in Ukraine
Authors: Boiko Lidiia
Published: July 2023

The relevance of the chosen topic is determined by its importance in the context of the modern professional education system in Ukraine. This is influenced by contemporary trends: the need for highly qualified specialists, the improvement of the quality of educational services, and the implementation of innovations. Accordingly, the growing role of electronics in the modern world creates the need for highly qualified bachelors in Electronics. Analyzing the factors that affect the quality of academic education in this field will help identify key aspects that will contribute to the training of competent specialists. The purpose of the research is to investigate various factors that influence the quality and effectiveness of academic education for students pursuing a degree in "Electronics" in Ukraine. Considering the multifaceted manifestations, functional ambiguity of factors in the academic education of future bachelors in Electronics, their analysis required the use of a range of methods: search-oriented, analytical, comparative, systematization, documentation analysis, systemic, and synergetic. Within the framework of the research, three reports on the results of accreditation expertise of the bachelor's degree educational program in specialty 171 "Electronics" were selected from the State University of Intellectual Technologies and Communications, the National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute", and the National Aviation University. Based on the obtained results, it is worth noting that one of the key factors that can influence the quality of the academic training aimed at students is the qualification of teachers. The factor of the availability of the possibility of forming an individual educational trajectory for students is a relatively new but quite a relevant one. Another important factor is the quality of the educational program, which is the foundation for the activities at higher education institutions. The state of educational infrastructure, including the availability of modern equipment and laboratories that can help students acquire practical skills in Electronics, is no less important. It is appropriate to note that the listed factors can interact and influence the academic success of future bachelors in Electronics in Ukraine. To ensure students’ success, it is essential that universities properly take these factors into account and create favorable conditions for learning and development.
Organizaciones criminales. Apuntes desde la Teoría General de Sistemas Sociales
Authors: Guerra Edgar
Published: July 2023

Los estudios sobre grupos criminales han dejado de lado el análisis del fenómeno criminal y su infraestructura comunicativa. En particular, ha sido desestimada una mirada sociológica que plantee un análisis sistémico de lo criminal y que aporte rendimientos novedosos a la investigación convencional en el campo, a saber: que la despoje del lenguaje de primer orden que hoy en día estructura la investigación. El artículo se pregunta ¿cómo entender el fenómeno criminal desde el punto de vista de la teoría de los sistemas sociales? El texto es un ensayo teórico que se ilumina a partir del propio trabajo de campo del autor. El resultado es una propuesta para estudiar el orden social criminal, así como sus rendimientos funcionales.
Encargos de aseguramiento de información financiera prospectiva en contextos inestables
Authors: Pérez Jorge O.
Published: July 2023

Contextos inestables, como el de la economía argentina, representan riesgos significativos para las empresas que actúan en esos mercados. En los Encargos de Aseguramiento de Información Financiera Prospectiva se debe prestar especial atención a los eventos desencadenantes de una crisis macro, que podrían afectar sustancialmente la situación de las firmas examinadas. 
En este trabajo se plantean instrumentos de apoyo al auditor en el reconocimiento de los riesgos mencionados y el modo de analizarlos a través de la identificación y modelización de las variables intervinientes. De esta manera, podrá tener evidencias para saber si la entidad ha considerado adecuadamente las hipótesis en relación a los efectos posibles.
Bank failure risk: A study on Silicon Valley Bank, Signature Bank, and Silvergate Capital Corporations
Authors: Hamurcu Çağri
Published: July 2023

This study investigates whether the ratio of long-term investment to total assets, the ratio of cash on hand to total assets, and the ratio of price-to-earnings are risk indicators for bank failures. Silicon Valley Bank (SVB), Signature Bank, and Silvergate Capital Corp., which experienced bank failure, and banks that are among the 20 largest banks in the USA are analyzed with the panel data method. Analyses were made using quarterly data between 2003Q4 and 2022Q4. It is revealed that the long-term investment to total assets ratio increases the bank failure risk. The risk of bank failure varies negatively with the cash on hand to total assets ratio. Bank failure risk rises as the price-to-earnings ratio rises. In terms of revealing the factors influencing the risk of bank failure and possible consequences, it is expected that the findings obtained could contribute to the literature.
Studies on Saturation Diving in Poland and Practical Application of their Findings. Part 2A. Developing a Polish System of Saturation Diving in the 1980s and 1990s
Authors: Skrzyński Stanisław , Grzeczka Grzegorz
Published: July 2023

This is another from the series of papers discussing studies on saturation diving technology and its use in Poland. This part explains the specificities of the Polish context and achievements against the backdrop of economic and historical circumstances. It describes how the central base for saturation diving came into being in the times of economic collapse in the country. At that time, the shipbuilding industry was the driving force behind research on saturation diving as a cornerstone for building a framework for diving systems to be exported to other countries to secure the extraction of assets from the sea shelf. The paper introduces the readers to the efforts of animators and protagonists of that period of underwater research in Poland whose achievements are continued until to-date. The second part of the paper shows how the Polish system of saturation diving was created. The article also considers the technical and organisational aspects of the first saturation diving experiences and the history of the Polish method of decompression for saturation diving. To accomplish this difficult task, it was crucial to ensure a solid industrial and academic base working for the defence sector and assisted by relevant state agencies. A multiannual CPBR programme was also set up with measures 9.2 and 9.5 dealing with medicine and technology which resulted in the development of a diving system with its organization, medical support and reliable technology. Outcomes of this programme are still being implemented today. Despite progress made in medicine, technology, and organisation issues involved in saturation diving are still pertinent because independently of their complexity and high cost this type of diving is the most efficient and allows for very deep diving operations up to 400-500 m.
An Attempt to Assess the Effectiveness of a Rescue and Starting Jump as Part of Activities Carried Out in Designated Water Areas Directly in Deep Water
Authors: Kaca Marcin , Siermontowski Piotr
Published: July 2023

Water rescue is constantly looking for solutions to improve the effectiveness of its operations. One of the elements of an action carried out directly in water is the rescue jump, whose effectiveness may determine the quality and success of the action taken. Therefore, a study was carried out to assess the effectiveness of a rescuer reaching a drowning person depending on the method of entry into the water. Comparisons were made between a traditional rescue jump (forward or stride entry) and a start jump used in sports. The observations also took into account factors related to the location of the operation (swimming pool, inland), the distance from the shore and the depth of immersion of the drowning person. The results show a significantly longer time for the rescuer to reach the drowning person after the rescue jump as compared to the start jump. Under standard swimming conditions, regardless of the distance and depth of immersion of the drowning person, all subjects reached the victim in the first attempt. Observations carried out in the conditions of designated inland water areas revealed comparable effectiveness in finding a simulated drowning person submerged to a depth of 2m and a significantly shorter time to reach them in favour of the start jump.
Who Is More Rational During a Crisis Situation: Men Who Do Not Spend Their Money or Women Who Think About the Future?
Authors:   Bucharest University of Economic Studies, Bucharest, Romania, Ichim Alexandru-Mihăiță , Panduru Andrei Dorian
Published: July 2023

The COVID-19 pandemic was one of the most important events in entire world history. This event changed and influenced human lives forever. The changes in human behavior were so relevant when the pandemic started. Furthermore, due to the recorded data and our personal experiences, research on this subject can serve as an instrument to reduce and minimize the impact of future health crises. We need to analyze, study, and draw significant conclusions to understand as much as possible how consumers reacted in order to avoid such situations in the future. In this article, I analyze data obtained from a survey about the consumer behavior of agro-food products during the COVID-19 crisis. Specifically, I study the influence of gender on the financial resource allocation of consumers of agro-food products during the lockdown period of March to June 2020. This analysis was performed using linear regression with binary variables. We can develop plans and safety measures based on the results and conclusions of the article. We also can use the article results and conclusion to have an image of consumer behavior toward agro-food products during health crises, to know how we can action. On the other hand, the analysis can be very helpful for retailers of agro-food products. They can develop new marketing or sales strategies based on the findings to maximize their income. These new strategies can be utilized during health crises, maximizing the opportunity presented.