bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Seismic Demand for Substandard Reinforced Concrete Structures
Authors: Kyriakides Nicholas , Sohaib Ahmad , Pilakoutas Kypros , Neocleous Kyriakos , Chrysostomou Christis , Tantele Elia , Votsis Renos
Published: February 2018

Background:

Reinforced Concrete (RC) buildings with no seismic design exhibit degrading behaviour under severe seismic loading due to non-ductile brittle failure modes. The seismic performance of such substandard structures can be predicted using existing capacity demand diagram methods through the idealization of the non-linear capacity curve of the degrading system, and its comparison with a reduced earthquake demand spectrum.

Objective:

Modern non-linear static methods for derivation of capacity curves incorporate idealization assumptions that are too simplistic and do not apply for sub-standard buildings. The conventional idealisation procedures cannot maintain the true strength degradation behaviour of such structures in the post-peak part, and thus may lead to significant errors in seismic performance prediction especially in the cases of brittle failure modes dominating the response.

Method:

In order to increase the accuracy of the prediction, an alternative idealisation procedure using equivalent elastic perfectly plastic systems is proposed herein that can be used in conjunction with any capacity demand diagram method.

Results:

Moreover, the performance of this improved equivalent linearization procedure in predicting the response of an RC frame is assessed herein.

Conclusion:

This improved idealization procedure has been proven to reduce the error in the seismic performance prediction as compared to seismic shaking table test results [1] and will be further investigated probabilistically herein.
The Governmentality of Promoting Ex-Gay “Change” in the Public Sphere
Authors: Thorn Michael E.
Published: February 2018

Background: A long-term “earned media” marketing strategy deployed by the Christian ex-gay movement backfired and now generates mostly negative media against the movement.

Analysis A governmental discourse analysis is used to examine media coverage representing conservative Christians struggling against unwanted same-sex desire. It does so in relation to Jürgen Habermas’ (2006) analysis of commercial media and Anna McCarthy’s (2007) notion of “neoliberal theatre of suffering.”

Conclusion and implications: Media coverage of the ex-gay debate showcases suffering as entertainment and does not achieve the full reasoned deliberation Habermas calls for in the public sphere. Nevertheless, it has not led to a paralysis of society’s ability to debate the issue of ex-gay “change.” Competing governmental perspectives still intersect and modify each other in ways that extend beyond mere commercialism.
Understanding Older Canadian Workers’ Perspectives on Aging in the Context of Communication and Knowledge Transfer
Authors: de Blois Sarah , Lagacé Martine
Published: February 2018

Background The Canadian population is aging, as is the Canadian workforce, resulting in an increase in different generations working with one another. The current study aims at understanding, from the older worker’s point of view, generational perceptions in the workplace, and further how such perceptions are linked with communication patterns as well as knowledge transfer.

Analysis This study collected 167 responses from a survey of older workers. The questionnaire addressed variables under study such as intergenerational perceptions, and workplace communication and collaboration patterns.

Conclusion and implications Results suggest that older workers perceived that their younger peers view them positively. Furthermore, older workers rely on accommodative communication patterns and favor knowledge transfer when interacting with younger colleagues.
Fuel as a Factor in Canadian Transport: Energy Capital and Communication Theory
Authors: Greaves Matthew
Published: February 2018

Background Established in 1849, the Fort Rupert coal settlement represented a departure in the Hudson’s Bay Company’s mode of colonial wealth accumulation on Vancouver Island. Company officials failed, however, to appreciate basic differences in the new mode of accumulation, including the importance of transportation to capitalist mineral extraction.

Analysis This article accomplishes three things: it retrieves foundational theories of transportation and commodity circulation once popular in communication studies, provides a documentary account of coal mining and the coal trade in the mid-nineteenth-century eastern Pacific, and articulates a theory of capitalist energy consumption.

Conclusion and implications The culminating theory of energy capital positions the extraction and circulation of fuel within Canadian communication studies through a transportation-focused approach to communication.
Rethinking the Cultural Icon: Its Use and Function in Popular Culture
Authors: Truman Emily
Published: February 2018

Background The role of cultural icons in twenty-first century North American popular culture has been under-theorized in communication scholarship. This is a significant gap in knowledge, given the importance of the icon as a public text through which collective cultural values are symbolized.

Analysis Using the novel approach of the scoping review, this article illuminates the current landscape of iconic studies by identifying wide-ranging examples of the cultural icon from academic scholarship, recognizing organizational categories, and synthesizing existing definitions to highlight the limits of current conceptualizations.

Conclusions and Implications Informed by the collected data, this article suggests a redefinition of the cultural icon that considers its current novel role in revealing tensions between different articulations of collective cultural values.
Negotiating What Constitutes Depression: Focus Group Conversations in Response to Viewing Direct-to-Consumer Advertisements for Antidepressants
Authors: Babineau Christine , McMullen Linda , Downe Pamela
Published: February 2018

Background  Direct-to-consumer (DTC) advertisements for medication communicate a distinct image of illness and have the potential to shape how we understand what constitutes illness.Analysis  The purpose of this study was to explore discursive patterns in how women interact with the messages related to depression in DTC television advertisements for antidepressants. We conducted six focus groups of 1 to 2 hours, with 4 to 6 female participants per group. Within each group, participants viewed and discussed 2 to 3 DTC advertisements.Conclusions and implications  Using discourse analysis to explore how the women engaged with the messages in the advertisements, we show how participants reclaimed what constitutes “normal” and “depression” and often positioned the ads as falling short in their presentations of these categories.Keywords  Antidepressants; Discourse analysis; Advertisement; DepressionContexte  La publicité directe au consommateur (PDC) sur les médicaments véhicule une image particulière de la maladie qui peut infléchir notre avis sur ce qu’est celle-ci.Analyse  L’objectif de cette étude était d’explorer des structures discursives relatives à la manière dont les femmes perçoivent les messages sur la dépression communiqués par des PDC sur les antidépresseurs. Pour ce faire, nous avons mené six groupes de discussion d’une à deux heures comptant 4 à 6 femmes par groupe. Au sein de chaque groupe, les participantes ont regardé et commenté 2 ou 3 PDC.Conclusion et implications  Nous avons effectué une analyse du discours afin d’explorer la manière dont les femmes interprètent les messages des PDC. Nous montrons comment les participantes se sont accordées sur le sens de « normal » et de « dépression » tout en percevant les PDC comme inadéquats dans leur présentation de ces concepts.Mots clés  Antidépresseurs; Analyse du discours; Publicité; Dépression
“You Talkin’ to Me?”: The Implied Reader in Canadian Business Magazine
Authors: Grandy Karen
Published: February 2018

Background  This Research in Brief asks whether the implied reader of Canadian Business is gendered and exclusive of women, as claimed in the November 2013 Letters to the Editor of that magazine.Analysis  To answer this question, the author examined article subjects, illustrative photographs, and textual signals of the implied reader in all the style and fashion articles (43 in total) published in the magazine over five years, 2010 to 2014.Conclusion and implications  The analysis confirms the letter writers’ complaint that women readers are largely excluded from the implied audience of these articles.Keywords  Magazines; Business media; Gender; Narratology; Implied readerContexte  Cette Recherche en bref cherche à voir si le lecteur implicite de Canadian Business est mâle à l’exclusion des femmes, tel que le prétend une lettre à l’éditeur parue dans ce magazine en novembre 2013.Analyse  Pour s’adresser à cette question, l’auteure a examiné des sujets d’articles, des photos représentatives et des interpellations du lecteur implicite pour tous les articles de style et de mode (43 en tout) publiés dans le magazine pendant cinq ans (de 2010 à 2014).Conclusion et implications  L’analyse confirme la plainte dans la lettre à l’éditeur selon laquelle les lectrices ne comptent pas parmi les lecteurs implicites de ces articles.Mots clés Magazines; Médias d’affaires; Genre; Narratologie; Lecteur implicite
A política dos sentimentos e a questão social no século XIX
Authors: Martins Ana Paula Vosne
Published: February 2018

Neste artigo propomos uma aproximação da questão social conforme ela foi definida no século XIX por filantropos e filantropas que por meio de diferentes ações e instituições procuraram responder, mesmo que de maneira pontual e mitigatória, aos problemas decorrentes do pauperismo. O objetivo é compreender as múltiplas dimensões da benevolência, seus agentes e seus desdobramentos políticos, bem como propor uma reflexão sobre as relações entre os sentimentos e a política social.
O Mato Grosso entre o “estigma do de(sertão)” e a “bravura bandeirante”: projetos de desenvolvimento por meio das páginas da “Série Realidade Brasileira” e da revista “Brasil-Oeste”
Authors: Salgueiro Eduardo De Melo
Published: February 2018

Neste artigo busca-se fazer uma discussão a partir de dois veículos de imprensa, quais sejam, a revista Brasil-Oeste e a Série Realidade Brasileira, a respeito de uma série de representações que historicamente incomodavam os grupos dirigentes mato-grossenses e ainda se faziam presentes em meados do século XX. Deste modo, o que apresento é o incômodo que resultava dessas representações e algumas das proposições para que esse quadro fosse invertido. Isso significa dizer que, a partir daquelas imagens que estigmatizavam, os mato-grossenses buscavam reformulá-las utilizando seus elementos negativos para, sob uma nova leitura, reconstruí-la. No decorrer do texto, serão vários os exemplos que poderão ilustrar tais afirmações.
CNBB, democracia e participação popular (1977-1989)
Authors: Senra Alvaro De Oliveira
Published: February 2018

O presente artigo busca analisar a documentação produzida pela Conferência Nacional dos Bispos do Brasil (CNBB) entre os anos de 1977 e 1989, tendo como recorte as proposições desta entidade sobre a democracia e a participação popular. A CNBB teve grande relevância política ao longo dos anos abordados, herdando do período do Regime Militar (1964-1985) o papel de articulador de extensos segmentos da sociedade civil. A análise da documentação produzida pela entidade, acompanhada de sua contextualização histórica e do debate com a bibliografia de referência utilizada, permitiu revelar a relação da CNBB com os pressupostos do catolicismo progressista.
RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis
Authors: Hagiwara Shinji , Sourris Karly , Ziemann Mark , Tieqiao Wu , Mohan Muthukumar , McClelland Aaron D. , Brennan Eoin , Forbes Josephine , Coughlan Melinda , Harcourt Brooke , Penfold Sally , Wang Bo , Higgins Gavin , Pickering Raelene , El-Osta Assam , Thomas Merlin C. , Cooper Mark E. , Kantharidis Phillip
Published: February 2018

Signaling via the receptor of advanced glycation end products (RAGE)—though complex and not fully elucidated in the setting of diabetes—is considered a key injurious pathway in the development of diabetic nephropathy (DN). We report here that RAGE deletion resulted in increased expression of fibrotic markers (collagen I and IV, fibronectin) and the inflammatory marker MCP-1 in primary mouse mesangial cells (MCs) and in kidney cortex. RNA sequencing analysis in MCs from RAGE−/− and wild-type mice confirmed these observations. Nevertheless, despite these gene expression changes, decreased responsiveness to transforming growth factor-β was identified in RAGE−/− mice. Furthermore, RAGE deletion conferred a more proliferative phenotype in MCs and reduced susceptibility to staurosporine-induced apoptosis. RAGE restoration experiments in RAGE−/− MCs largely reversed these gene expression changes, resulting in reduced expression of fibrotic and inflammatory markers. This study highlights that protection against DN in RAGE knockout mice is likely to be due in part to the decreased responsiveness to growth factor stimulation and an antiapoptotic phenotype in MCs. Furthermore, it extends our understanding of the role of RAGE in the progression of DN, as RAGE seems to play a key role in modulating the sensitivity of the kidney to injurious stimuli such as prosclerotic cytokines.
KAJIAN TINGKAT PEMAHAMAN KONSEP INTEGRASI ILMU DAN ISLAM ANTARA DOSEN BIDANG ILMU UMUM DENGAN DOSEN BIDANG ILMU AGAMA DI FAKULTAS ILMU TARBIYAH DAN KEGURUAN UIN SYARIF HIDAYATULLAH JAKARTA
Authors: Ansharullah Ansharullah
Published: February 2018

This research is aimed to know the level of difference of Comprehension on the Concept of Integration of Science and Islam between Social - Science and Islamic Science Lecturer at Faculty of Education and Teacher Training of UIN Syarif Hidayatullah Jakarta based on the educational background, the lecturer Expertise, and the frequency of attending training on Integrating Islam and Science in Education. All lecturers were taken as sample in this research by using purposive sampling. The data was collected by using test and documentation. Then, The data was analyzed by using t-test. The results are (1) Based on the educational background of lecturer; Islamic university - graduated lecturer and Public university – graduated lecturer, the Ho hypothesis is rejected, (2) Based on the frequency of attending trainings on Integration of Science and Islam, the Ho hypothesis is accepted and, (3) based on the expertise, the Ho is rejected.
KONFIGURASI PEMIKIRAN AL-QABISI TENTANG PENDIDIKAN ISLAM
Authors: Musir Muslim
Published: February 2018

As a jurist, Hafiz al-Qur`an and hadith as well as a good understanding Arabic, al-Qabisi offer educational concepts based al-Qur`an and Sunnah, which impressed normative paradigm of thinking. However, the environmental conditions when it still has relevance to the concept offers, so that form the guidelines for teaching children during the fourth century hijrah. In principle, the development of the Islamic education concept does not just stop in textual normative, need depth assessment of various aspects, sociological, geographical, or philosophy of a nation itself. Very unlikely set curriculum or teaching methods and educational purposes based on one aspect only. Advanced education in the perspective of al-Qabisi can be seen from the realization of the religious environment in the various regions of Islam at the time. Is a natural thing when he established the concept of education that guided in his time.
Calculations used for assessment of rapid maxillary expansion
Authors: Bartok Ruxandra , Dimitriu Bogdan  Dimitriu , Vârlan Constantin , Stanciu Radu , Moldoveanu Georgiana , Gagniuc Paul , Suciu Ileana , Gheorghiu Irina-Maria , Mitran Loredana , Mitran Mihai , Suciu Ioana
Published: February 2018

Rapid maxillary expansion is defined as the release of medio-palatine suture using an orthopedic forces. The role of this procedure is to expand  the upper jaw in order to achieve the  broadening of the upper arch. This study was initiated to quantify the effects of disjunction and post- treatment bone changes, after an adequate contention which lasted for three weeks. This study  is  carried on laboratory animals (common breed rabbit) to determine tensile strength and the elasticity modulus of  biological materials  used in orthdodontics. The results of the study are consistent with those reported in the literature reference.
Diagnostic confusion in paediatric respiratory pathology. Case report
Authors: Zamfir-Chiru-Anton Adina A. , Gheorghe D.C.
Published: February 2018

The authors present the case of a 4-year-old child admitted to the ENT Department with possible pulmonary foreign body aspiration. A detailed history revealed a clinical picture that seemed to depict an absence episode (with partial loss of conscience and cianosis) occured when eating, less the symptomes of a respiratory foreign body. Diagnosis needed full respiratory endoscopy and neurologic evaluation for correct assesment and effective therapy approach.
Vestibular migrain in clinical practice
Authors: Roceanu A. , Băjenaru O.
Published: February 2018

Vestibular migraine is one of frequently met etiologies of central vertigo; clinical characteristics are association of vertigo signs and migrainous headache. Criteria for classification of the vestibular migraine were established together by Bárány Society and International Headache Society (IHS).
Diagnostical considerations in Guillain-Barré syndrome
Authors: Bălănescu M. , Gheorghe D.C. , Zamfir-Chiru-Anton Adina A.
Published: February 2018

The authors report a pediatric Guillain-Barré syndrome, masquerading as an acute respiratory tract infection, more specifically acute croup, occurring in a 16-month-old child. The diagnostic approach and therapy of such cases rely on close cooperation between the ENT specialist, pediatrician, as well as other specialists.
Language evolution post stroke in newborn and infant age
Authors: Sandu Magdalena , Sterea Ramona , Teleanu Raluca Ioana
Published: February 2018

Perinatal stroke is defined as a vascular cerebral injury that takes place before the age of  28 days, and it usually includes the in utero periode. The vascular lesion can, however, happen even in infancy, due to various causes. Stroke has a lower incidence at infant age, but a higher rate of recognition due to the more obvious clinical manifestations. The incidence of stroke reaches 1/3000 children, with long-term consequences on motility, predisposition to epileptic seizures, communication skills and learning ability. Pediatric stroke implies large costs in order to rehabilitate and reintegrate the child socially. This paper aims to analize the evolution of language at a distant point in time, after the occurrence of the injury, with cases from our clinical experience.
External auditory meatus cavernous hemangioma - case report
Authors: Sandul A. , Buracovschi M. , Buracovschi N.
Published: February 2018

Benign vascular tumors are common in the head and neck region, but they rarely occur in the external auditory canal. The authors present a case of cavernous hemangioma in a 50-year-old patient admitted to the Clinical Republican Hospital. Computed Tomography and Nuclear Magnetic Resonance imaging revealed the presence of a tumor that almost totally occupied the external auditory canal. The vascular tumor was excised by endaural approach. The external auditory canal regained its original shape.
Polipous chronic middle ear otitis – case report
Authors: Sandul A. , Buracovschi M. , Buracovschi N. , Gusacinschi I.
Published: February 2018

The authors present a case of chronic polyposis otitis media in a 32-year-old patient treated in Clinical Republican Hospital. Computed tomography revealed the presence of an aural polyp which originated from middle ear ossicles. The aural polyp was surgically removed through microdebridation and a type II Wullstein tympanoplasty was performed.
Swallowing rehabilitation in a case of giant parapharyngeal tumor. Case report
Authors: Mitran Loredana , Gavrilă I.G. , Seceleanu Vlad Petrescu
Published: February 2018

The authors present a case of giant parapharyngeal prestilian space tumor (over 10 cm in diameter) with histological aspect of pleomorphic adenoma of the salivary glands, which caused progressive swallowing impairment. The peculiarity of this case is the date of onset of symptomatology - after 10 years of relative silent evolution, with relative stationary size - an imagistically documented fact. Swallowing rehabilitation, complete only after 10 days postoperatively, pleads for a neural substrate associated with mass effect rather than a simple mechanism of intraluminal pharyngeal obstruction in explaining the cause of this impairment.
Therapeutic strategies for locally advanced laryngeal cancer. Part 1: Radical treatment
Authors: Pitiu Corina , Enăchescu Ciprian , Yossi Sena , Crismariu Gianina Elena
Published: February 2018

According to the Union for International Cancer Control (UICC)/ American Joint Committee on Cancer (AJCC), staging system for the locally advanced laryngeal cancer generally denotes stage III or IV, stage III being represented by T3 or N1 tumors and the non-metastatic stage IV including N2-N3 or T4 tumors. The main therapeutic goals are local control and survival, but also the functional organ preservation (speech, swallowing and airway patency), if possible. To achieve these objectives, the management should be established by a multidisciplinary tumor board, based on the analysis of patient-specific factors (age, performance status, comorbidities, and psychosocial support), cancer topography and staging, but also the physician expertise and the availability of rehabilitation services. Regarding the larynx preservation, there are two major therapeutic strategies: total laryngectomy (associated with adjuvant radio- and chemotherapy) and larynx preservation strategy, which includes neoadjuvant chemotherapy followed by exclusive radiotherapy or concurrent radio-chemotherapy or radio-biotherapy. Total laryngectomy can be performed by open surgery or, in order to avoid a wide surgical field and reduce the local morbidity, by transoral techniques. After laryngectomy, the recurrence can be local, at the resection site, nodal, at cervical lymph nodes, or distal, the lung being the most common site of recurrence as a distant metastasis. To improve locoregional control and survival, adjuvant treatments are proposed, including radiotherapy, chemo- and biotherapy.
Malignant melanoma of nasal mucosa, ethmoid and frontal sinuses endoscopically resected in the combined transnasal and trans-paralateronasal approach
Authors: Mocanu Bogdan , Mirea Daniel , Oprescu Silviu , Vișan Anca , Tușaliu Mihai , Ciocâlteu Alina , Mocanu Constantin , Mocanu Georgeta
Published: February 2018

Introduction. The primitive malignant melanoma of nasal mucosa and paranasal sinus is a rare tumor of uncertain etiology, with unpredictable biologic behavior and bad prognosis. Unlike skin melanomas, there are no risk factors and the disease is frequently manifested in older patients, whose clinical otorhinolaryngology complaints are normally non-specific and ranges from nasal obstruction to rhinorrhea and epistaxis. Unfortunately, this disease is diagnosed basically in advanced stages which makes the surgery difficult. Objective. To report a case of primitive malignant melanoma of nasal mucosa, ethmoid and frontal sinuses, that was diagnosed in 2015. It was performed a subtotal resection in another hospital in 24.08.2015, with a large local reccurence. Report. Our patient was a 78-year-old woman with bilateral nasal obstruction, light epistaxis and unilateral rhinorrhea. The ENT, CT and  MRI exams showed a tumour with important, invasion of the nasal cavity structures (billateral nasal bones, left frontal process of the maxilla, the superior midpoint of the nasal septum, bilateral middle and superior turbinates, left ethmoid and bilateral frontal sinuses). The patient was submited for surgery: total macroscopic resection in the combined endoscopic approach; transnasal and modified lateral rhinotomy with titaniul plates reconstruction of the external nose architecture. Conclusions. Malignant melanomas of nasal mucosa are, in general, diagnosed in advanced stages. Their histological characteristics in the mucosa makes difficult the surgical treatment, which is one of the most efficient options, because they are resistant to chemo and radiotherapy. The early diagnosis and a good surgical treatment plan are the best option for this tumor nowadays.
Giant thyroid tumours - therapeutic difficulties
Authors: Vrînceanu Daniela , Axinte V. , Bănică Bogdan
Published: February 2018

Introduction. Thyroid tumors are a borderline pathology approached equally by endocrine surgeons, ENT surgeons, thorax surgeons or general surgeons. The cooperation with the endocrinologist is mandatory in preoperative balance sheet, but also in postoperative treatment. The large size of a thyroid tumor (over 10 cm) causes a big surgical risk and a special preoperative preparation. Material and method. We present two cases of giant thyroid tumors: an anaplastic carcinoma developed on a papillary carcinoma and a medullar carcinoma.  We present our therapeutic options for every single case, including the surgical treatment in mixed team with thorax surgeon‚ “long time hard surgery”. In one case we performed intubation on bronchoscope to avoid tracheotomy, and in the other case we made preoperative embolization. Results. The immediate therapeutic result depends on team work with thoracic surgeon, with the endocrinologist and intensive care specialist. The final therapeutic result depends on complex oncological treatment, but also on clinical and endocrine supervision. Discussions. The decision to operate a giant thyroid tumor had to put in balance risks and benefits maybe more than in other types of head and neck tumors because of the major intraoperative risk of bleeding and of bilateral injury of recurrent nerves. Conclusions. The surgical indication must be assessed judiciously. Preoperative (endocrine and general) complete clinical balance is indispensable. The surgical intervention has to be well prepared by both patient and surgeon. Effective therapeutic result depends on the interdisciplinary collaboration and on patient compliance to treatment.
Retrospective study on parotid gland tumors
Authors: Cioranu Ibric , Seceleanu Vlad Petrescu , Cioranu Viorel Ibric , Smarandache Andreea , Vasilescu Sorin , Mitran Loredana
Published: February 2018

During 2011-2012, 56 patients diagnosed with parotid tumors were admitted to the Maxillofacial Surgery Department of “Lucian Blaga” University and in Euroclinic Hospital. 72% were benign tumors and 28% malignant. All patients received surgical treatment (total or partial parotidectomy). For the malignant tumors, radiotherapy was added to the modal treatment (94% of the cases). Pleomorphic adenoma was encountered in 70% of the benign cases, followed by Warthin tumor in 15%. Adenoid cystic carcinoma was noticed in 31% of the malignant cases, mucoepidermoid carcinoma in 25% of the cases, and squamous carcinoma and non-Hodgkin lymphoma on 12.5% of the malignant cases.
Papilloma virus - potential cause of oropharyngeal and laryngeal cancers
Authors: Ataman Marius
Published: February 2018

The author reviews the Papillomaviruses potentially responsible for the occurence of oro-pharyngo-laryngial cancers in humans, as well as the procedures used in their identification by molecular techniques.
Chondrosarcoma of the larynx - case report
Authors: Szalontay Andreea Silvana , Boloș Alexandra , Cozma Sebastian
Published: February 2018

In recent decades, advances in medical research brought major changes in the understanding and management of mental retardation. Children with mental retardation may associate many somatic and psychiatric disturbances and also hearing impairment in 10% of cases. However, for children with mental retardation, a delay in speech will be noted. Many children have dyslalic speech and a reduced vocabulary. They understand basic speech, but they are not always accessible to more complex verbal expressions. Comorbidity with hearing loss will result in a more difficult language development in these children, requiring a collaborative team with psychiatrist, ENT specialist, psychologist, speech therapeut, with the earliest detection of sensory impairment and, as much as possible, adjusting it to allow the development to the maximum capacity of these children. It is necessary to apply early intervention, to stimulate individual available capacity by using specific psycho-pedagogical measures and appropriate treatments for correcting auditory difficulties.
Play- and dramatherapy - complementary techniques for rehabilitation of children with cochlear implant
Authors: Cernea Magdalena
Published: February 2018

The present interactive research-action-training project, looking at the young cochlear-implanted subjects from a multidisciplinary holistic perspective, was based on the theory on psychosocial development of human beings, the attachment theory, language development theories and the concept of resilience. The integrative approach suggests two creative therapeutic styles (play- and dramatherapy) as means of intervention of neuro-dramatic play. The study starts from the hypothesis that creative therapies will help young children wearing cochlear implants at social integration in the peer groups of normal-hearing children and teenagers. This integrative approach will facilitate developement of teamwork abilities by improving their self-esteem and self-image. We included children and their families in an assisted resilience process with expert paticipation in the field of social and political development of Romanian non-guvernamental organisations. Material and method. The research-action-training project targets 3-18-year-old deaf children and teenagers wearing cochlear implants or hearing aids. The study considered a group of 72 deaf children and teenagers, as well as 49 normal-hearing subjects of similar ages, who were observed during the whole therapeutic program. Specific techniques were: painting, drawing, modelling, sand, miniatures, sensorial and corporal plays, role play, improvisation, body movement, music, dance, mimic and masks. The professional teams (psychologists, dramatherapists, educators, medical assistants, students at the school of play- and dramatherapy, film directors) who worked with and supervised these children and teenagers during the whole project (whose coordinator was helped by 12 volunteers) assured a secured and relaxed atmosphere, observing rules which did not restrict young subjects’ freedom of expression. Results. The positive results show the necessity to implement creative therapies during the auditory-verbal rehabilitation of the young deaf subjects. 42% (of the young subjects) improved their body movements, 27% acquired better projection strategies, 67% ameliorated their ability of interpreting a role, and 72% got pro-risk scores. The results are accompanied by significant images shot during the program activities. Conclusions. Parallelling the audio-verbal therapy, the play- and dramatherapy are important complementary remedial treatments in stimulating the means of expression and communication of children and teenagers wearing cochlear implants.
Melatonin in pediatric neurology
Authors: Teleanu Raluca Ioana , Sandu Magdalena , Roza Eugenia
Published: February 2018

Melatonin  is a hormone produced by the pineal gland during the night, as a response to the light-darkness variation. The endogenous melatonin levels have a cyclic evolution throughout the entire life. Various roles have been cited such as the in utero developement of the fetus through its action on the placenta, neurons and glial cells, a major role in the regulation of the cyrcadian rhythm, antioxidative, antiinflammatory roles, as well as celullar and umoral immunity modulation. In the European Union, exogenous melatonin has been evaluated by the European Food Safety Authority (EFSA) for reducing sleep onset latency and the conclusion was that it has efficacy studies in this regard.
Concha bullosa mucocele - endoscopic surgical solution
Authors: Costache Andreea Nicoleta , Ioniţă C. , Guligă Alexandra , Panfiloiu A. , Decuseară Tatiana  , Budu Vlad Andrei , Tușaliu Mihai
Published: February 2018

Headache is a borderline pathology, faced by physicians of various specialties, which has to be thoroughly investigated to establish the etiology and appropriate treatment. The authors present a case of concha bullosa mucocele managed by endoscopic sinus surgery. The mucocele was responsible for persistent nonsystemized headache and also for the chronic rhinosinusitis of the maxillary, ethmoidal and frontal sinus because of the blockage of the middle meatus. The drainage of the anterior sinuses and the mucocele of the concha bullosa were successfully managed by endoscopic sinus surgery.
Applying Machine Learning Techniques to Predict the Properties of Energetic Materials
Authors: Elton Daniel , Boukouvalas Zois , Butrico Mark S. , Fuge Mark D. , Chung Peter W.
Published: February 2018

We present a proof of concept that machine learning techniques can be used to predict the properties of CNOHF energetic molecules from their molecular structures. We focus on a small but diverse dataset consisting of 109 molecular structures spread across ten compound classes. Up until now, candidate molecules for energetic materials have been screened using predictions from expensive quantum simulations and thermochemical codes. We present a comprehensive comparison of machine learning models and several molecular featurization methods - sum over bonds, custom descriptors, Coulomb matrices, bag of bonds, and fingerprints. The best featurization was sum over bonds (bond counting), and the best model was kernel ridge regression. Despite having a small data set, we obtain acceptable errors and Pearson correlations for the prediction of detonation pressure, detonation velocity, explosive energy, heat of formation, density, and other properties out of sample. By including another dataset with 309 additional molecules in our training we show how the error can be pushed lower, although the convergence with number of molecules is slow. Our work paves the way for future applications of machine learning in this domain, including automated lead generation and interpreting machine learning models to obtain novel chemical insights.
Bonded Force Constant Derivation of Advanced Glycation End-Products: DOGDIC, GODIC, and MODIC
Authors: Nash Anthony , de Leeuw Nora H , Birch Helen L
Published: February 2018

The computational study of advanced glycation end-product cross- links remains largely unexplored given the limited availability of bonded force constants and equilibrium values for molecular dynamics force fields. In this article, we present the bonded force constants, atomic partial charges and equilibrium values of the arginine-lysine cross-links DOGDIC, GODIC and MODIC. The Hessian was derived from a series of ab initio quantum mechanical electronic structure calculations and from which a complete set of force constant and equilibrium values were generated using our publicly available software, ForceGen. Short in vacuo molecular dynamics simulations were performed to validate their implementation against quantum mechanical frequency calculations.
Bonded Force Constant Derivation of Lysine-Arginine Cross-linked Advanced Glycation End-Products
Authors: Nash Anthony , de Leeuw Nora H , Birch Helen L
Published: February 2018

The computational study of advanced glycation end-product cross- links remains largely unexplored given the limited availability of bonded force constants and equilibrium values for molecular dynamics force fields. In this article, we present the bonded force constants, atomic partial charges and equilibrium values of the arginine-lysine cross-links DOGDIC, GODIC and MODIC. The Hessian was derived from a series of ab initio quantum mechanical electronic structure calculations and from which a complete set of force constant and equilibrium values were generated using our publicly available software, ForceGen. Short in vacuo molecular dynamics simulations were performed to validate their implementation against quantum mechanical frequency calculations.
Effect of Infrared Light on Protein Behavior in Contact with Solid Surface
Authors: Kowacz Magdalena , Warszynski Piotr
Published: February 2018

Adsorption of proteins at a solid surface affects characteristics of the surface (e.g. its biocompatibility) and functionality of the immobilized biomacromolecules. The latter is defined by the type of binding sites, protein conformation and its structural flexibility that enable functional motions to occur. Protein motions are only possible at certain level of hydration. Furthermore, water molecules act as lubricant facilitating sliding along solid surface. In this work we explore the potential of a remote physical trigger –a non-ionizing infrared radiation (IR) to affect protein-surface interactions. We report on IR-induced changes of hydrophilicity of the protein coatings on silica nanoparticles, impact of IR on monitored in-situ dynamic adsorption of proteins on silica surface and effect of IR on conformational state of adsorbed proteins. Our results indicate that IR can protect proteins from surface denaturation depending on the presence of strongly hydrated amino acid residues. Preservation of native fold results in protein coatings of higher hydrophilicity. IR can also facilitate displacement of surface activespecies that became adsorbed to protein apolar compartments and couldotherwise promote denaturation. Apart from supporting native conformation, their removalincreases protein-water interfacial tension and therefore promotes aggregation (hydrophobic attraction) of the protein-coated nanoparticles. By its ability to affect protein conformational state and interfacial characteristics (such as effective protein-water affinity) IR radiation can therefore modulate protein interactions.
Identificación del porcentaje de Síntomas Psicopatológicos en alumnos de la Media de una institución privada de la Ciudad de San Lorenzo. Departamento Central, Año 2017
Authors: Quintana Romina Carolina , Ojeda Gómez Ana María
Published: February 2018

La psicopatología es la fundamentación científica de la psiquiatría, estudia la conducta desviada. Un síntoma es una señal o indicio de algo que está sucediendo o va a suceder, una manifestación subjetiva de un estado patológico. Mientras que un trastorno es la alteración leve de la salud, una enajenación mental. Esta investigación es un estudio de Síntomas Psicopatológicos en los alumnos de la Media de una Institución privada de la Ciudad de San Lorenzo.  Objetivo: Identificar el porcentaje de los Síntomas Psicopatológicos que presentan los alumnos del Primer al Tercer Año de la Media de una Institución privada de la Ciudad de San Lorenzo, ubicada en el Departamento Central, en el Segundo Periodo del Año 2017.
Empoderamiento de enfermería en las unidades de cuidados intensivos. Hospital Central del Instituto de Previsión Central
Authors: Villagra Rivera Nancy , Ruoti Mónica
Published: February 2018

El empoderamiento es el proceso por el cual las personas fortalecen sus capacidades, su confianza, su visión y protagonismo para impulsar cambios positivos de las situaciones que viven, por ello es un desafío para los profesionales de enfermería en todos los niveles de asistencia. En las unidades de cuidados intensivos, la condición del enfermo crítico requiere vigilancia continua y quien dispensa este servicio es el enfermero/a asistencial. Pese a ser importantes en la evolución de los enfermos, los profesionales de enfermería muestran un perfil bajo en relación a otros miembros del equipo de salud. Sus acciones son silenciosas, carecen de evidencia y principalmente, muestran desorganización individual y colectiva. Las propuestas de Marc Zimmerman en materia de empoderamiento y Patricia Benner en lo relacionado el desarrollo profesional de enfermería constituyen el enfoque teórico desde donde se aborda la problemática.
Uso de indicadores ambientales como aproximación a un Marco de Referencia Territorial
Authors: Chyrnia Lisnichuk Laura Analía
Published: February 2018

El distrito de San Juan del Paraná-Paraguay ha sufrido grandes transformaciones en la última década, afectando la forma de vida de sus habitantes y aumentando considerablemente la presión sobre los recursos naturales. La elaboración de diagnósticos ambientales es una tarea ardua y multisectorial que demanda tiempo y conlleva altos costos, sin embargo, sería más beneficioso hacer esta labor de una manera rápida y eficaz, minimizando gastos en el proceso de evaluación para invertirlos directamente en programas que solucionen diversas problemáticas. Una mejor opción es la aplicación de indicadores ambientales que simplifiquen el proceso de búsqueda de información, integren datos multidisciplinarios y aporten un conocimiento comparable y más profundo con un gasto menor, y que pueden ser aplicables según la realidad de cada territorio.
GRAPHIC - Groundwater and Climate Change - Small Island Developing States
(SIDS)
Authors: Meyer Chloé
Published: February 2018

The purpose of this paper is to summarize the (I) current state of
groundwater on SIDS, (II) potential impacts of climate change to groundwater on
SIDS, and (III) importance of groundwater resources in climate change mitigation
on SIDS. GRAPHIC’s SIDS studies are highlighted, including several from the
Pacific, Caribbean, and other regions of the globe. This paper is part of a
series of GRAPHIC publications following the release of the GRAPHIC position
paper in 2015.

Climate change
Groundwater
SIDS
GRAPHIC - Groundwater and Climate Change - Mitigating the Global Groundwater
Crisis and Adapting to Climate Change Impacts - Position Paper and Call to
Action
Authors: Meyer Chloé
Published: February 2018

The purpose of this paper is to highlight the important role groundwater has
in meeting the demands for drinking water, agricultural and industrial
activities, and sustaining ecosystems, particularly in the context of adaptation
to and mitigation of the impacts of climate change. This paper outlines several
key recommendations that are particularly relevant for future international
climate negotiations.

Climate change
Groundwater
Water, Megacities and Global Change - Portraits of 15 emblematic cities of
the world
Authors: Meyer Chloé
Published: February 2018

This overview of 15 emblematic cities, co-edited by UNESCO and ARCEAU-IdF,
is simultaneously the result of concrete scientific presentations and a call for
general mobilization to devise the sustainable urban policies the world needs.
All these urban centres share a number of common characteristics: expansive
size, disparities between rich and poor districts, environmental and industrial
demand that strains the natural resources of an entire region – not to mention
the economic weight of the country as a whole – and a wide range of cultural,
scientific and educational resources.

Human settlements
Megacities
SIDS
Volume of surface water leaving countries in 2014
Authors: Meyer Chloé
Published: February 2018

This layer represents the average volume of surface water that left the
country to other countries in 2014. It refers to water leaving through
transboundary flow (rivers, canals, pipes) in km3/year, but not to water flowing
to the sea through The table also provide information on the volume of surface
water leaving a country and that is not submitted to formal agreements or
treaties, the volume which is submitted to treaties, and through formal
agreements or treaties, all in km3/yr.

For more information, please see this example of the calculation rules:
http://www.fao.org/nr/water/aquastat/data/wrs/readPdf.html?f=AFG-WRS_eng.pdf

Visit the FAO Aquastat website at:
http://www.fao.org/nr/water/aquastat/data/query/index.html?lang=en

Agreement
Surface water
Vulnerability
Volume of surface water entering countries in 2014
Authors: Meyer Chloé
Published: February 2018

This layer represents the average volume of surface water that entered the
country in 2014 through transboundary flows. The table also provide information
o

For more information, please see this example of the calculation rules:
http://www.fao.org/nr/water/aquastat/data/wrs/readPdf.html?f=AFG-WRS_eng.pdf

Visit the FAO Aquastat website at:
http://www.fao.org/nr/water/aquastat/data/query/index.html?lang=en

Transboundary
Agreement
Surface water
Vulnerability
Transboundary water resources of the world
Authors: Meyer Chloé
Published: February 2018

This map presents 286 transboundary river basins (2016) and 592
transboundary aquifers (2015).

154 countries share river basins or aquifers with one or more of their
neighbours. Some of this countries (30) lie entirely within one or more
transboundary basins, making this shared resource a essential one.

The extent of those transboundary resources highlights the importance for
countries to cooperate with each other for the sound management of shared
waters.

Basin
Groundwater
Transboundary
BAKTERI ENDOFIT KULIT BATANG TERAP (ARTOCARPUS ELASTICUS) DAN AKTIFITASNYA SEBAGAI ANTIBAKTERI
Authors: - Guplin , Jekti Dwi Soelistya Dyah , Zulkifli Lalu
Published: February 2018

This study aims to identify the types of endophytic bacteria on the bark of terap (Artocarpus elasticus) capable of inhibiting the growth of clinical isolate bacteria of Staphylococcus aureus, Escherichia coli, Salmonella typhi, and Pseudomonas aeruginosa. Stages of this study were (1) isolating the endophytic bacteria from the bark of terap plants (2) antibacterial test (inhibition test) against clinical isolate bacteria, (3) biochemical test upon endophytic isolate bacteria showing strong  inhibition effect, (4) moleculer identifcation upon endophytic bacteria isolate showing strong  inhibition effect. From this study, it was obtained 34 barks of terap isolates, and 12 isolates have inhibitory effect on S. aureus. Based on 16S rRNA   molecular identification, the isolate of endophytic bacteria of the barks were identified as Bacillus cereus, Bacillus subtilis and Bacillus amyloliquefaciens. Those  endophytic bacteria of Terap plants  are potentially  to be  developed as a the producer of antibacterial compounds.Keywords: Terap bark, Endophytic bacteria, Identification, Antibacteria
Poor body condition and diet diversity in a harvested population of fishers
Authors: Kirby Rebecca , Freeh Carissa , Gilbert Jonathan H. , Olson John F. , Pauli Jonathan N.
Published: February 2018

Though fishers Pekania pennanti were extirpated from most of their historical range in the United States, they have successfully repatriated many areas, and are now legally harvested in the Great Lakes region. Recent harvests and winter track surveys, however, suggest fisher populations may again be decreasing in northern Wisconsin. We investigated potential factors contributing to this purported decrease by quantifying fisher diet in northern Wisconsin via stable isotope analysis (δ13C and 615N) and examining body condition of individual fishers using measurements of fat depots. Diet reconstruction revealed small mammals and porcupines constitute the largest portions of fishers' diets in Wisconsin. Body condition analyses showed that contemporary fishers carry significantly less body fat compared to Wisconsin fishers two decades ago and to two other regional populations. Our findings contrast with past regional studies that report snowshoe hares and white‐tailed deer carrion as the largest components of fisher diet. We suggest the diet and body condition of fishers in Wisconsin could be due to low availability of preferred prey other than porcupines on the landscape, which may be contributing to the recent putative population decrease.