bluuebunny/crossref_metadata_2025 huggingface dataset:
Coproparasitological research in birds housed at the Sargento Prata Zoo, Fortaleza - Ceará, Brazil
Authors: Lemos L. B. S. , Marques A. R. , Lima B. P. , Dias B. V. A. , Fontão C. C. , Ribeiro C. D. S. , Freitas C. M. P. , Schwinden G. M. , Sampaio I. F. , Silva I. N. G. , Melo L. S. , Melo M. V. C. , Pascoal Filho N. M. , Alves P. V. , Teixeira R. S. C. , Maciel W. C.
Published: October 2024

Abstract Birds kept in captivity are subject to various diseases that affect their well-being, with parasites being among the most common. The aim of this study was to report the occurrence of endoparasites in the feces of birds kept in captivity at Fortaleza Zoo, using the Willis Mollay and Hoffman techniques. Of the samples analyzed, 50.98% were positive for endoparasites, including the suborder Coccidia, the genera Capillaria spp., Strongyloides spp., Ascaridia spp., Libyostrongylus spp., cysts of a specific parasite of Ostriches, Balantidium spp., the Strongyloidea superfamily and cestodes. In conclusion, the wild birds in the zoo investigated had a diversity of endoparasites and a considerable infection rate.
Investigating the hepato-protective properties of chamomile oil and olive leaves extracts against ribociclib-induced hepatotoxicity
Authors: Alsarhan A. A. , Khwaldeh A. S. , Al-Shawabkeh J. D. , Shoiab A. A , Al-Shdefat R. , Al-Fawaeir S. , Yousef I.
Published: October 2024

Abstract A new approach to overcome or reduce these toxicities is by using antioxidants. Ribociclib, a CDK4/6 inhibitor used in the treatment of breast cancer, has been linked to hepatotoxicity and may contribute to the development of Hepatocellular carcinoma in rats. This Study aims to assess hepatoprotective effect of chamomile oil and olive leaf extracts against ribociclib-induced Hepatotoxicity in rats. A total of 40 adult male albino rats aged 9-10 weeks were utilized in this experiment. These rats were divided into four groups, (N=10). Group A (control) comprised normal rats administered 1 ml (10 ml/kg/day) of normal saline daily. Conversely, group B rats were administered 5 mg/kg Ribociclib (n = 10), while group C was administered 5 mg/kg Ribociclib with a 500 mg/kg/day dose of chamomile oil. Group D was given 5 mg \kg Ribociclib in combination with 200 mg/kg/day of olive leaves. After the trial, the animals were sacrificed, blood samples were collected for biochemical tests, and the liver tissue was processed for histological examination. The results of histology, and biochemistry parameter analysis, indicated that co-administration of Ribociclib and chamomile oil plays a decisive role in mitigating the hepatotoxicity result from Ribociclib-induced liver injuries in rats as demonstrated by histological and biochemical parameters.The levels of cholesterol and LDL in the blood were significantly lower (P < 0.01) after administering chamomile oil compared to the control group. The results of the current study demonstrated that the simultaneous use of chamomile oil and olive leaf extract significantly reduced the liver damage caused by Ribociclib and improved the lipid profile in Albino rats. Additionally, the use of chamomile extract notably lowered urea levels (p < 0.01), indicating a protective effect on the kidneys.
Análise da eficácia do tratamento endovascular com escleroterapia por espuma na síndrome de congestão pélvica através de avaliação por ultrassonografia
Authors: Gava Natália Miranda , Silva Amanda Santana , Maciel Gustavo Sasso Benso , Assis Márcia Porto , Santos Carlos André Daher
Published: October 2024

Resumo Contexto A síndrome de congestão pélvica (SCP) é uma importante causa de dor pélvica em mulheres adultas, levando à redução da qualidade de vida, abstenção no trabalho, ansiedade, depressão e distúrbios sexuais. Objetivos Avaliar a resposta ao tratamento endovascular por escleroterapia com espuma para varizes pélvicas e traçar o perfil das pacientes com esse diagnóstico acompanhadas no Hospital das Clínicas Cassiano Antônio Moraes, da Universidade Federal do Espírito Santo. Métodos Com base na revisão de prontuários, este estudo descritivo retrospectivo analisa o perfil e a resposta das pacientes submetidas ao tratamento endovascular de varizes pélvicas por escleroterapia com espuma. As variáveis analisadas incluem idade, peso, altura, índice de massa corporal (IMC), paridade, queixa de dor pélvica e critérios ultrassonográficos, comparando o diâmetro dos vasos pélvicos pré e pós-procedimento, e a presença de refluxo venoso ao Doppler transvaginal. Resultados As pacientes analisadas tinham em média 43,3 anos, 2,95 gestações e IMC de 25,37kg/m2. A avaliação ultrassonográfica após intervenção indicou uma redução estatisticamente significativa (valor de p < 0,005) do calibre dos vasos parauterinos, com diâmetro médio de 6,34 mm à direita e 7,26 mm à esquerda antes do procedimento e, respectivamente, 4,37 mm e 4,56 mm após o procedimento. Conclusões A escleroterapia com espuma reduziu o calibre das varizes pélvicas na amostra estudada, com resultados semelhantes aos de outras modalidades de tratamento endovascular dessa comorbidade. A realização de mais estudos prospectivos para avaliação da resposta a essa intervenção se faz necessária para firmá-la como uma opção eficaz para o tratamento da SCP.
Tratamento de lesões penetrantes de veia cava retro-hepática: protocolo de revisão sistemática
Authors: Góes Junior Adenauer Marinho de Oliveira , Abib Simone de Campos Vieira , Kleinsorge Gustavo Henrique Dumont , Vieira Daniella Adrea Araujo Rossi , Nakano Luis Carlos Uta
Published: October 2024

Resumo Lesões do segmento retro-hepático da veia cava inferior requerem procedimentos complexos, pois sua exposição sem controle vascular prévio pode acarretar sangramentos incoercíveis e letais. Para este controle, a tríplice exclusão vascular hepática e o implante de shunt átrio-caval foram classicamente descritos e, mais recentemente, estratégias endovasculares foram relatadas. Entretanto, não há consenso na literatura sobre qual dessas estratégias apresenta menor mortalidade. Com a finalidade de definir qual estratégia terapêutica apresenta menor mortalidade e incidência de complicações no tratamento de lesões penetrantes do segmento retro-hepático da cava inferior, será realizada uma revisão sistemática da literatura, a qual foi registrada na plataforma PROSPERO sob o número CRD42023464133. O Cochrane Handbook for Systematic Reviews of Interventions será utilizado para orientar o processo. As buscas serão realizadas nas bases de dados MEDLINE/PubMed, LILACS, Embase, Scopus e Web of Science. O site ClinicalTrials.gov e a Plataforma Internacional de Registro de Ensaios Clínicos (ICTRP) serão consultados para a detecção de ensaios em andamento ou não publicados. Os estudos serão selecionados por uma estratégia de busca previamente estabelecida, o montante de resultados será filtrado utilizando-se o aplicativo Rayyan, e os estudos incluídos serão analisados independentemente por dois autores para construção do senso final. A análise qualitativa dos estudos será feita com a ferramenta RoB 1.0.
Treatment of penetrating injuries of the retrohepatic vena cava: systematic review protocol
Authors: Góes Junior Adenauer Marinho de Oliveira , Abib Simone de Campos Vieira , Kleinsorge Gustavo Henrique Dumont , Vieira Daniella Adrea Araujo Rossi , Nakano Luis Carlos Uta
Published: October 2024

Abstract Injuries to the retrohepatic segment of the inferior vena cava require complex procedures, as exposure without prior vascular control can lead to uncontrollable and fatal bleeding. To achieve such control, the classic techniques of hepatic vascular exclusion and the implantation of an atriocaval shunt have been described, and more recently, endovascular strategies have been reported. However, there is no consensus in the literature regarding which of these strategies is associated with lower mortality. In order to determine which therapeutic strategy presents the lowest mortality and complication rates in the treatment of penetrating injuries to the retrohepatic segment of the inferior vena cava, a systematic review of the literature will be conducted, registered on the PROSPERO platform under the number CRD42023464133. The Cochrane Handbook for Systematic Reviews of Interventions will guide the process. Searches will be carried out in the MEDLINE/PubMed, LILACS, Embase, Scopus, and Web of Science databases. ClinicalTrials.gov and the International Clinical Trials Registry Platform (ICTRP) will be consulted to detect ongoing or unpublished trials. Studies will be selected based on a predefined search strategy, the number of results will be filtered using the Rayyan app, and the studies included will be independently reviewed by two authors to reach a final consensus. The qualitative analysis of the studies will be conducted using the RoB 1.0 tool.
Ophidian accident in horses in the Amazon Biome, Pará, Brazil
Authors: Serruya Analiel , Lopes Cinthia T.A. , Silveira Natália S.S. , Barbosa Camila C. , Costa Paulo S.C. , Duarte Marcos D. , Campos Karinny F. , Barbosa José D.
Published: October 2024

ABSTRACT: Bothrops atrox is the most common viper in the Amazon, and its venom causes local and systemic changes. This report describes the clinicopathological and laboratory findings of ophidism due to Bothrops in six horses in Pará, Brazil. The animals, which belonged to five different rural properties, showed clinical signs of apathy, anorexia, and increased touch sensitivity in areas of increased volume. Three animals were bitten in the distal part of the pelvic limbs and three in the head area. The affected animals in the distal limb area exhibited marked edema extending from the fetlock to the thigh and had difficulty moving. Those affected in the head region exhibited an increase in volume that gave the appearance of a “rhinoceros head,” as well as blackening of the mucosa of the lips and gums. All animals exhibited tachycardia and tachypnea, and laboratory findings of two animals showed anemia, leukocytosis, increased clotting time, and elevated liver (AST and GGT) and kidney enzymes (urea and creatinine). Treatment was ineffective, and three of four treated animals died. Necropsy was performed on three animals, revealing extensive hemorrhage in the tissues at the snake bite sites and incoagulable bloody fluid in the cavities. Congestion was observed in the diaphragm, in the serosa of the small intestine, and in lighter areas on the renal surface. Histopathology showed muscle degeneration, necrosis, acute tubular necrosis, hemorrhage, and hyaline casts in the kidneys. This case report highlights the clinicopathological findings of snakebite in horses. In addition, this seems to be the first report of bothropic envenom in a mule in Brazil.
Quality of life of caregivers and drug-resistant epilepsy children treated with a ketogenic diet
Authors: Mendonça Cecilia Nascimento de , Henriques-Souza Adélia Maria de Miranda , Viana Larissa de Andrade , Souza Paula Azoubel de , Alves Neto Luis Bandeira , Mello Maria Júlia Gonçalves de
Published: October 2024

ABSTRACT Objective To assess caregivers’ burden and quality of life of children and adolescents with drug-resistant epilepsy treated with ketogenic therapy. Methods Survey-type study involving caregivers of children and adolescents being monitored at the ketogenic diet clinic of the Instituto de Medicina Integral Prof. Fernando Figueira. Socioeconomic data were collected from the patients’ medical records. Telephone interviews with the guardians of the child/adolescent were carried out using two instruments: 1) The Quality of Life of Children with Epilepsy, which approaches the physical, psychological, cognitive/educational and socio-familial domains from the parents perspective,; and 2) The Zarit Burden Inventory, which assesses the impact of chronic mental disorders on the physical and emotional well-being, social life and financial aspects of the caregiver. Results The sample consisted of 49 children and adolescents of caregivers with a median age of 44 years, 61;2% of whom were male. The results obtained using the Quality of Life of Children with Epilepsy showed that after the cognitive/educational domain, the domain most impaired was the physical domain (median=52.8, Q1=47.2; Q3=61.1) and the most preserved was the psychological domain (median=77.8; Q1=70.8; Q3=83.3). The burden was considered moderate to severe for the majority (55.1%) of caregivers. Conclusion A poor quality of life for the child/adolescent and an increase in the caregiver’s burden were observed, interfering in the daily life and personal relationships of the guardians. Thus, the multidisciplinary team should also offer support and appropriate technical support to caregivers.
Indicadores de sustentabilidade e rede de cooperativas de catadores: uma avaliação do impacto no desempenho de suas organizações-membros
Authors: Pisano Viviane , Demajorovic Jacques , Besen Gina Rizpah
Published: October 2024

Resumo As Redes de Cooperativas de Catadores (ROC) são um fenômeno ainda pouco estudado na literatura e emergem como um modelo organizacional alternativo para superar os desafios enfrentados por seus integrantes ao melhorar seu desempenho por meio da comercialização conjunta e acesso direto às indústrias recicladoras. Esta pesquisa tem como objetivo avaliar o impacto das ROC no desempenho de suas organizações-membros. Para esse objetivo, uma adaptação de indicadores de sustentabilidade de cooperativas propostos por Besen et al. (2017) foram aplicados em 3 redes, sendo seus resultados posteriormente triangulados com a análise documental e entrevistas. Os resultados apontam que houve ganhos para as organizações estudadas no que se refere a ampliação da coleta e separação de recicláveis, aumento da produtividade e renda, viabilização de vias logísticas, maior equidade de gênero no ambiente de trabalho e melhoria das condições de saúde e segurança e fortalecimento político dessas organizações. Também foram identificados desafios para o funcionamento deste arranjo organizacional, destacando-se o desnivelamento estrutural entre os empreendimentos que compõem as ROC, conflitos entre os objetivos das ROC e necessidades mais imediatas das cooperativas membros e ainda a necessidade de balancear o apoio governamental na construção das ROC sem comprometer seu necessário grau de emancipação e autogestão.
Jovens aprendizes: trabalhadores efetivamente comprometidos e/ou ajustados aos papéis organizacionais?
Authors: Costa Silas Dias Mendes , Lara Samara de Menezes , Paiva Kely César Martins de
Published: October 2024

Resumo O objetivo neste estudo foi analisar comparativamente os níveis de comprometimento afetivo e consentimento organizacional de jovens aprendizes brasileiros. Realizou-se um estudo com 2.543 jovens aprendizes, coletando-se dados com escalas validadas de comprometimento afetivo e consentimento organizacional. Na análise de dados, primeiro foram feitas análises fatoriais confirmatórias; na sequência, interpretação dos resultados; por fim, testes de correlação. Os resultados coadunam-se com outras evidências da estrutura unidimensional dos construtos, ratificando a base afetiva do comprometimento afetivo e a obediência no consentimento organizacional. A média geral de comprometimento afetivo foi inferior à de consentimento organizacional. Tais resultados informam tanto um vínculo afetivo elevado, quanto fortes ajustes a papéis e obediência. Dada a realidade socioeconômica dos aprendizes e possíveis variáveis explicativas, sugere-se uma agenda para estudos futuros.
Cartografia das controvérsias da telemedicina no Brasil
Authors: Bueno Daniela de Cunto , Tavares Elaine
Published: October 2024

Resumo Esta pesquisa tem como objetivo identificar, descrever e relacionar actantes e controvérsias da telemedicina no Brasil com base na regulamentação da prática pelo Conselho Federal da Medicina (CFM). Com apoio da teoria ator-rede (Callon, 1987; Latour, 1987; Law, 1992) e usando a metodologia da cartografia de controvérsias, o percurso metodológico passou pela coleta e pela análise de notícias de jornais, dados da primeira consulta pública do CFM sobre telemedicina e entrevistas com 15 médicos. Nela, foram identificados os atores-rede porta-vozes da telemedicina e um mapa das controvérsias encontradas, as quais têm origem na associação do corporativismo com as possibilidades da materialidade, a relação médico-paciente e as interseções dessas controvérsias. Outras controvérsias tomam forma e se relacionam com responsabilidade civil, ética, questões financeiras, de infraestrutura e geográficas.
Economia circular e reivindicações de nexo social
Authors: Freitas Florence Cavalcanti Heber Pedreira de , Araújo Edgilson Tavares de , Oliveira Rodrigo Teles Dantas de , Amorim Rodrigo Mascarenhas
Published: October 2024

Resumo Este ensaio busca analisar questões sobre a emergência da economia circular (EC), com ênfase nas limitações referentes a valores e inclusão social de trabalhadores da reciclagem. As reflexões foram construídas sob uma óptica acerca de desigualdades e exclusões sociais que podem emergir da EC no Brasil caso ela seja implementada sem os devidos reconhecimento e valorização dos principais atores da reciclagem no país: os catadores. Com este artigo, esperamos contextualizar os debates a respeito da economia circular, integrar as contribuições recentes de estudos críticos sobre o tema e discutir reivindicações quanto à potencialidade da gestão social, a fim de promover a inclusão social e a governança na agenda política de projetos de EC no Brasil.
Bacio di Latte: experiência gastronômica de excelência em canais digitais
Authors: Oliveira Gustavo Franco de , Girão Mel
Published: October 2024

Resumo Nascida na capital paulista, a Bacio di Latte é uma das referências brasileiras no segmento de sorvetes - ou gelato, como eles preferem - de alto valor agregado. Em pouco mais de 10 anos de uma trajetória bem-sucedida, a sorveteria se estabeleceu em todo o território brasileiro, com mais de 130 unidades próprias, além de uma crescente e vitoriosa operação de distribuição em supermercados. Você acaba de ser contratado como head de marketing e encontra uma empresa que tem passado por um período delicado em suas operações, dado o fechamento das lojas e dos shoppings em virtude da pandemia. Porém, percebe também que a crise acelerou os negócios de alimentação em direção aos canais digitais, o que traz oportunidades e desafios. Caberá a você a liderança desse projeto, que pode representar o próximo salto de crescimento da Bacio di Latte.
Domestic accidents due to children’s falls: a cross-sectional study
Authors: Silva Abiúde Nadabe e , Nogueira Lídya Tolstenko , Silva Ana Roberta Vilarouca da
Published: October 2024

ABSTRACT Objective: To describe the occurrence of domestic accidents due to children’s falls. Method: This is a descriptive, cross-sectional study carried out with 181 parents and/or other caregivers of children aged between 2 and 5 years. Data were collected in March and April 2024, through a questionnaire containing 23 items, which were subjected to descriptive analysis. Results: The sample was composed mostly of mothers (93.9%), with a predominance of female children (52.2%), and 86.2% of infants suffered some type of fall at home. Falls from bed (56.4%), hitting the head/face (52.6%), mainly causing cuts/lacerations (16%), were predominant. Conclusion: The results show that it is essential to raise awareness among families about the imminent responsibility of protecting children from domestic accidents, protecting them from injuries that can be avoided through changes in behavior and adopting a proactive stance by intervening in anticipation of risk factors.
Acidentes domésticos por queda infantil: estudo transversal
Authors: Silva Abiúde Nadabe e , Nogueira Lídya Tolstenko , Silva Ana Roberta Vilarouca da
Published: October 2024

RESUMO Objetivo: Descrever a ocorrência de acidentes domésticos por queda infantil. Método: Trata-se de estudo descritivo, transversal, realizado com 181 pais e/ou outros cuidadores de crianças com idade entre 2 e 5 anos. Os dados foram coletados nos meses de março e abril de 2024, por meio de um questionário que contém 23 itens, os quais foram submetidos à análise descritiva. Resultados: A amostra foi composta em sua maioria por mães (93,9%), com predomínio de crianças do sexo feminino (52,2%), sendo que 86,2% dos infantes sofreram algum tipo de queda no domicílio. Predominaram quedas da cama (56,4%), atingindo a cabeça/face (52,6%), ocasionando, principalmente, corte/laceração (16%). Conclusão: Os resultados evidenciam que é imprescindível sensibilizar as famílias quanto à iminente responsabilidade de proteger as crianças dos acidentes domésticos, resguardando-as de lesões que podem ser evitadas por meio de mudanças de comportamentos e adoção de uma postura proativa ao intervir de forma antecipatória nos fatores de risco.
NURSE MANAGERS’ ETHICAL PROBLEMS IN HOSPITAL SETTINGS: AN ANALYSIS FROM THE MACINTYRIAN PERSPECTIVE
Authors: Cunha Simone Graziele Silva , Deodato Sérgio , Ramos Flávia Regina Souza , Caram Carolina da Silva , Brito Maria José Menezes
Published: October 2024

ABSTRACT Objective: to understand hospital nurse managers’ ethical problems from the perspective of Macintyre’s virtue ethics. Method: qualitative research of the single case study type, encompassed by Alasdair Macintyre’s theoretical framework of virtue ethics. Sixteen nurses in management positions participated in the study for a minimum period of six months. The setting was a university hospital in Belo Horizonte, Brazil. Data were collected between August and October 2021, through individual interviews with a semi-structured script and document analysis, analyzed using Bardin’s content analysis. Two categories of ethical problems emerged from the thematic analysis linked to violations of care values: internal goods; and linked to breaking norms, patterns of behavior and interpersonal relationships: external goods. Results: the ethical problem is present in care, in relationships and in the institution. When referring to the profession’s internal assets, ethical problems are characterized as a violation of care values: denial of assistance, negligent and reckless actions or violation of the rights of professionals, patients, staff and institutions. When referring to external goods, such problems are linked to interruption of norms, inappropriate actions and behaviors or ethical conduct questioned and disrespected by professionals. Conclusion: nurse managers understand ethical problems as circumstances that generate opposition to actions considered correct and that go against what is proper to nurses and against their duty, negatively affecting professionals, patient care, the institution and the public service.
CRIANÇAS E HISTÓRIA: O TEMPO COMO CONCEITO E A NARRATIVA DA TEMPORALIDADE
Authors: Leopoldino Maria Aparecida
Published: October 2024

Resumo O artigo problematiza a ênfase no tempo cronológico nas aulas de História para crianças nos primeiros anos do ensino fundamental, refletindo sobre o tempo histórico. Retoma-se a perspectiva de Koselleck para pensá-lo como conceito, assim como o relaciona com a narrativa, como tratou Ricoeur, e, fundamentalmente, compreende-o na relação entre a experiência da infância e a memória, tal como abordou Walter Benjamin. Ressalta-se a experiência do narrar e da memória na aprendizagem de temporalidades, destacando o seu lugar na experiência histórica que interessa à discussão sobre a aprendizagem diante da proposta da Base Nacional Comum Curricular. Conclui-se que esse caminho possibilita especificar a História não apenas como uma disciplina escolar, mas também como prática social.
History of pain and dental care in individuals with Autism Spectrum Disorder during the Covid-19 pandemic from the perspective of caregivers
Authors: Souza Priscila Siqueira Ribeiro de , López Muriel Denisse Rivera , Azevedo Marina Sousa , Costa José Ricardo Sousa , Schardosim Lisandrea Rocha
Published: October 2024

ABSTRACT Objective: Assess the history of pain and dental care before and during the COVID-19 pandemic, as well as the resolution of the dental problems in individuals with ASD from the perspective of caregivers. Methods: Caregivers from three associations of individuals with ASD in the state of Rio Grande do Sul were invited to answer an online questionnaire. They answered questions distributed into three sections: I) identification data of the patient with ASD and his caregiver; II) perception of dental access before the pandemic (until March/2020) and III) perception of dental access during the pandemic (March/2020 until 2022). Data were tabulated into a Microsoft Excel spreadsheet and analyzed using descriptive statistics. Results: Of the 473 caregivers for individuals with ASD in the contacted groups, 72 (15.2%) responded to the survey and were included in this study. Before the COVID-19 pandemic, individuals with ASD had experienced dental pain (23.7%). Twelve of these (70.6%) allowed dental care, according to the caregivers’ reports. Regarding the experience of pain during the pandemic, 20 individuals with ASD (27.8%) felt pain, and 17 of them had also experienced pain before the pandemic. Conclusion: The difficulty of dental access faced by families and individuals with ASD is a reality, and the persistence of dental pain history was similar before and during the COVID-19 pandemic. The preference for services in the public sector prevailed; however, the majority did not find a resolution to their issues, emphasizing the need for improvements in oral health care for this population.
Historiography and empathy: Critical School Psychology actions on self-injury practices
Authors: Silva Nadja Maria Vieira da , Almeida Rodrigo da Silva , Bezerra Henrique Jorge Simões
Published: October 2024

Abstract Objective Intervention research in the field of Critical School Psychology based on historiographical assumptions. The objective was to investigate the current meanings of non-suicidal self-harm in educational environments. Method In the workshops, psychology students were prepared to put themselves in the shoes of a person with a history of non-suicidal self-harm. Later, these students wrote narratives about that person's past, their current experiences and future expectations. Results Aspects highlighted in the literature about the history of non-suicidal self-injury were also configured in the current meanings about self-mutilation described in the narratives of Psychology students. Psychology students modified their meanings about non-suicidal self-injury to empathize with people with this experience. Conclusion As the historiographical approach aims to explain current situations anchored in past events, it favors the planning of actions for educational environments committed to ethical and political aspects. The focus on empathy associated with a historiographical perspective on educational processes can be a way to design actions in the field of Critical School Psychology, given its commitment to the humanization of contemporary society.
O CURRÍCULO POR COMPETÊNCIAS NO CURSO DE EDUCAÇÃO FÍSICA NA UNIJUÍ: PROCESSO DE IMPLEMENTAÇÃO E IMPACTOS INICIAIS
Authors: Borges Robson Machado
Published: October 2024

Resumo O artigo apresenta o processo de implementação, bem como os resultados iniciais, do currículo por competências no curso de Educação Física na Unijuí. A partir das experiências como coordenador do curso e docente em componentes curriculares, o autor faz uma breve e concisa avaliação da implementação do currículo em seus dois primeiros anos. O texto é desenvolvido em uma perspectiva descritiva, organizado em cinco partes: indicação do contexto e os aspectos que influenciaram a criação de um novo currículo; apresentação da estrutura que compõe o currículo; descrição das escolhas metodológicas utilizadas no desenvolvimento do currículo; avaliação dos impactos iniciais da reestruturação e implementação do curso nos primeiros dois anos; apontamento de êxitos e dificuldades no processo. Os resultados indicam que o currículo atual tem possibilitado uma formação ampliada aos acadêmicos, considerando a análise da possibilidade de mobilização efetiva do que se estuda, em contraste com o campo profissional. Os acadêmicos consideram o novo modo de organização do curso produtivo, conferindo méritos aos procedimentos metodológicos e às atuações dos professores que visam o aprimoramento dos seus conhecimentos. A experiência de planejamento e estudo colaborativo permitiu aos professores qualificarem suas atuações e reconhecerem que precisam estudar permanentemente. Evidencia-se que, por um lado, ocorreram avanços em uma série de aspectos e, por outro, há pontos importantes a evoluir, uma vez que os docentes se movimentam e se posicionam em níveis diferentes, em relação ao planejamento, desenvolvimento e avaliação das aulas por competências.
EFEITO DA PROPRIEDADE INSTITUCIONAL COMUM SOBRE O TUNNELING: EVIDÊNCIAS EMPÍRICAS DA CHINA
Authors: Bai Yajie , Wu Maoguo
Published: October 2024

RESUMO Este estudo examina o papel da propriedade institucional comum (PIC) na redução do comportamento de tunneling dos acionistas controladores em empresas chinesas listadas em bolsa. Utilizando um modelo de regressão múltipla, a influência da PIC no comportamento de tunneling é examinada empiricamente. Os resultados mostram que a PIC restringe esse comportamento, sendo que esse impacto se intensifica com o aumento da PIC e com um índice de participação acionária mais alto. O efeito é mais acentuado em empresas com ambientes informacionais deficientes, baixa supervisão externa, de propriedade privada e cum um alto grau de separação entre propriedade e controle. Descobrimos que os investidores institucionais comuns amenizam o comportamento de tunneling usando a vantagem informacional e participando do ativismo de acionistas. Esses resultados oferecem novas evidências sobre o efeito dos investidores institucionais comuns no comportamento dos acionistas controladores.
Crise do sindicalismo no contexto da flexibilização e precarização do trabalho no Brasil
Authors: Farias Silvio Kanner Pereira , Schmitz Heribert
Published: October 2024

Resumo O objetivo deste artigo é discutir a relação entre os processos de flexibilização e precarização do trabalho e a crise do sindicalismo no Brasil. Nele, questiona-se a explicação da crise unicamente como resultado das mudanças no mundo do trabalho e das políticas neoliberais. Uma ampla revisão bibliográfica foi realizada sobre os temas abordados, seguida de uma discussão sobre os limites heurísticos desse modelo explicativo. Foram levantados dados sobre a evolução da densidade sindical no Brasil e pontos relevantes da dinâmica recente do sindicalismo. Como conclusão, constatou-se que as abordagens que ligam diretamente a crise do sindicalismo aos processos de flexibilização do trabalho e ao neoliberalismo são válidas para a perda de protagonismo político; diversas experiências empíricas de sindicatos específicos fogem, porém, desse modelo explicativo geral, o que indica a complexidade da realidade sindical e a relevância de uma abordagem dos processos sociais de organização e de mobilização no âmbito de cada sindicato.
Briefing: The London Surface Water Strategy
Authors: Rapoport Elizabeth
Published: October 2024

Surface water flooding (SWF) is one of the highest risks on the London Risk Register. The London Surface Water Strategic Group was formed as a response to the significant SWF events witnessed in London in July 2021. The London Surface Water Strategy is a collaboration between key organisations that have a role to play in SWF. The strategy will aim to increase London’s preparedness for SWF, while delivering benefits for Londoners, the environment and the economy. As part of the strategy, natural solutions to SWF, such as sustainable drainage systems, will be prioritised. One of the strategy’s key proposals for change is the introduction of catchment-based partnerships that will assist the many contributing parties in the implementation of projects across political and organisational boundaries. This collaboration between boroughs and other organisations will aim to increase London’s resilience to SWF.
A systematic review of construction skills acquisition in higher education institutions
Authors: Olubimbola Oladimeji , Haddad Assed Naked
Published: October 2024

Higher education institutions (HEIs) construction students’ skill acquisition is critical to addressing skill shortages in the AEC industry caused by issues such as an ageing workforce accompanied by rising retirement rates and the industry’s difficulty in attracting and retaining fresh talents due to their negative perceptions of the industry. Hence, this paper conducts a systematic literature review on construction skills accessed and acquired through the HEIs, especially at the commencement of the 4th industrial revolution of 2014. Seven hundred and forty-eight articles were analysed, of which 46 were selected through the PRISMA protocols. Meanwhile, the research limitations can be attributed to using specific crucial keywords in viable but constrained databases. Results from the analysis demonstrated the authors’ prominent use of mixed research methods. Findings and recommendations focused on construction students, graduates, HEIs, professionals, clients, and the digitisation of construction pedagogy. Significant findings and recommendations highlight the need to revise the construction curriculum and teaching methods, emphasising the importance of using digital tools and applications. A well-structured and implemented construction course curriculum tailored towards acquiring soft and hard construction skills will go a long way towards sustaining, improving, and increasing a viable construction workforce.
No prosody-syntax trade-offs: Prosody marks focus in Mandarin cleft constructions
Authors: Arnhold Anja
Published: October 2024

In line with the idea that language has evolved to be efficient and to avoid redundancy, syntactic means of marking information structure have been derived from prosodic ones, and vice versa, for many languages. On the basis of crosslinguistic comparisons, prosody-syntax trade-offs have frequently been described for clefts. The present study investigated whether such trade-offs can also be observed language-internally, testing whether clefting reduced prosodic focus marking in production or its effects on perception in Mandarin. A production study found that clefts showed prosodic focus marking equal to or exceeding that found in syntactically unmarked equivalents. In both syntactic conditions, focused constituents had larger f0 ranges, higher f0 maxima and longer durations compared to a broad focus baseline, while post-focal constituents showed lower f0 maxima and minima, lower intensity and, for clefts, shorter durations (28 participants, 937 utterances containing 4466 syllables analyzed in total). A rating study likewise found that the effect of prosody on the perception of information structure was not modulated by clefting, which neither affected ratings nor reaction times (102 participants, 2448 responses analyzed in total). These findings suggest that prosody is integral for marking focus in cleft constructions instead of constituting a redundant cue.
Clinical case of a live-born child with triploidy
Authors: Il’ina M. A. , Kolyadina D. V. , Shutkova A. Yu. , Yakimova O. N. , Zapevalova T. A. , Suslova M. A. , Khaletskaya A. I. , Yatsyshina E. Е. , Khaletskaya O. V.
Published: October 2024

Theoretical data on etiopathogenesis, clinical manifestations of triploidy, life expectancy of children in case of live-birth with this chromosomal anomaly are presented. A clinical case of a triploidy in a child is described. The girl was born from the first pregnancy from young healthy parents. Parents are not close relatives. Pregnancy was complicated with anemia, recurrent threats of miscarriage, progressive lack of water, progressive violation of uteroplacental blood flow and delay in fetal development. A congenital heart defect was diagnosed prenatally. The girl was born at 38 weeks of pregnancy with low indicators of physical development by caesarean section. Multiple developmental anomalies and malformations were revealed after birth. Combined congenital heart disease was confirmed by instrumental examination. Karyotyping revealed karyotype 69, ХХХ. Dynamic observation revealed that the child's age-related skills were not formed. Epileptic seizures occurred from the age of 4 months. The seizures had a status course. Surgical correction of congenital heart disease was performed in two stages: at 4.5 months and at 9.5 months in this patient. A fatal outcome occurred with an increase in multiple organ failure at the age of 10 months. The features of the clinical case, the possibilities of prenatal diagnosis of triploidy are analyzed.
Aszimmetrikus kihívások a haderő, az állam, valamint a társadalom viszonyában
Authors: Forgács Balázs , Kaló József , Németh József Lajos
Published: October 2024

„Mit ér a falon függő kard?” Szun-ce A fenti mottó példázza talán a legjobban azt a látszólagos egyszerűséget, ugyanakkor jelentéstani és filozófiai értelemben azt a bonyolultságot, amely az állam, a társadalom és a haderő vonatkozásában immár évezredek óta fennáll. Bár a jelzett megközelítést döntően a nukleáris eszközök stratégiai jelentősége kapcsán szokták idézni, mégis sajátos hangsúllyal és tartalommal ruházható fel akkor is, amikor az említett szereplők egymáshoz való viszonyát vizsgáljuk. Erre a vizsgálatra pedig nemcsak az időszakonként megújuló társadalmi és politikai igények miatt van szükség, hanem azért is, mert az állam, társadalom és haderő viszonya akkor is jelen van, ha az azok közötti kapcsolatok nem válnak el markánsan egymástól, vagy éppen nem fonódnak szinte elválaszthatatlanul össze.
Gondolatok az aszimmetrikus rendészeti kihívásokról és a lehetséges válaszokról
Authors: Fehér Zoltán
Published: October 2024

A mai konferencia délelőttjén az előadók körbejárták, és megpróbálták minden igényt kielégítően megfogalmazni az aszimmetrikus hadviselés fogalmát. Elhelyezték különböző korokban, vizsgálták a fogalmat tartalmi elemei szerint, illetve meghatározták, hogy milyen kritériumok tartoznak a fogalomkörhöz. Nekem, mint rendőrnek, aki e témakörben kevéssé járatos, teljesen egyértelművé vált, hogy egy olyan komplex kérdéskörrel állunk szemben, amelynek tartalmi kellékei koroktól, rendszerektől és a fogalom alkotójától nagymértékben függtek és függnek ma is.
A terrorizmus jelene és jövője
Authors: Sárkány István
Published: October 2024

Korunk egyik legfontosabb, legizgalmasabb kérdése, hogy Francis Fukuyama vagy Samuel Huntington gondolatait igazolják-e a jövőnk történései. Fukuyama álláspontja szerint a történelem nem egyéb, mint nagy szétbomlások és újjászerveződések sorozata. A modern demokráciákkal e sornak a végére értünk, az ideológiák köztiharc véget ért. Huntington állítása szerint az ún. endista álláspont téves, mert a politikai ideológiák civilizációkon belüli összecsapását a vallás és a kultúra civilizációk közötti összecsapása váltja fel, melynek következtében a nyugati civilizáció csak egy lesz a sok közül és nem is a legerősebb.
Hadtudományi kutatók és kutatási területeik
Authors: Munk Sándor
Published: October 2024

A hadtudomány részterületeire is érvényesíthető kritérium, hogy legyen önálló tárgyuk, legyenek művelőik, intézményrendszerük és tudományos irodalmuk. Jelen publikáció egy átfogó kutatás első részeredménye, amely az MTA hadtudományi köztestületi tagságának rendelkezésre álló adatai alapján elemzi kutatási területeiket, mutatja be az egyes területeket művelő kutatók számát, támpontot kívánva nyújtani ezzel a hadtudomány belső struktúrájára és külső kapcsolatrendszerére vonatkozó elemzésekhez, döntésekhez.
Csendben szolgálni
Authors: Szentgáli Gergely
Published: October 2024

A magyar biztonság- és védelempolitikával foglalkozó írások jelentős többsége a Magyar Honvédséget érintő kérdésekre korlátozódik. Az elmúlt politikai ciklusok biztonságot érintő értékelései döntő többségében katonapolitikai kérdéseket taglalnak, a politikai évkönyvek is (feltéve, hogy van biztonságpolitikai témával foglalkozó fejezetük) csupán a haderőreform eredményeire vagy eredménytelenségére fókuszálnak. A nemzetbiztonsági szektor ebből a szempontból még inkább elhanyagolt területnek számít, a szakmai elemzések elsősorban szűkebb (de fontos) problémaköröket vizsgálnak, míg az említett évkönyvekben is csupán a botrányokkal kapcsolatos beszámolók kapnak helyet. A kétrészes tanulmány célja, hogy áttekintse a magyar nemzetbiztonsági szektor helyzetét és az ott történt változásokat 2010 és 2014 között, a második Orbán-kormány hivatali idejére fókuszálva, ezzel is hozzájárulva a nemzetbiztonsági szakirodalomhoz. Jelen (első) tanulmányban a történelmi, politikai és jogi kereteket mutatom be, a második részben pedig a konkrét átalakításokat fogom górcső alá venni.
Demokratikus legitimáció, választási felhatalmazás és alkotmány a haderő mögött
Authors: Patyi András
Published: October 2024

A Magyar Honvédség tiszti, főtiszti utánpótlását biztosító Nemzeti Közszolgálati Egyetem civil irányítás alatt működő, ugyanakkor katonákat képző felsőoktatási intézmény. A konferencia szervezői fontosnak tartották, hogy mielőtt a fõ téma boncolgatása megkezdődik, fogalmazódjon meg néhány általános vagy elvi gondolat. Az előadás keretében három atipikus témakörrel kívánok foglalkozni. Ezek a következők:– Alkotmány a haderő mögött, (a védelmi alkotmány alapkérdései);– a választásokon elnyert felhatalmazás;– a demokratikus legitimáció. De mi köze is van a választásoknak egy ország fegyveres erejéhez?
Modern Didactics of Acute Pneumonia as a Side Effect of the Antibiotic Era
Authors: Igor Klepikov
Published: October 2024

The widespread and uncontrolled use of antibiotics for more than eighty years, including not only medicine but also the food industry, has had a significant impact on the usual relationships between representatives of the microbiosphere that accompanies our body. For a long time, the possibility of side effects remained without due attention, giving way to attempts to maintain the original antimicrobial effect of these drugs. Currently, evidence of the consequences of antibiotic therapy has received official recognition only in the form of resistant microflora. Phenomena such as the constant change of AP pathogens and the gradual loss of antibiotics for their purpose remain unstudied. The selective nature of specialists' attention to the side effects of antibiotics is due to a decrease in their effectiveness and the desire to restore the successes of previous therapy. The latter circumstance is a consequence of the negative didactic influence of antibiotics on professional views that determine the strategy for solving the problem and require, first of all, changes following the fundamental canons of medical science and numerous facts.
The Synergistic and Opposing Roles of ω-Fatty Acid Hydroxylase (CYP4A11) and ω-1 Fatty Acid Hydroxylase (CYP2E1) in Chronic Liver Disease
Authors: James P Hardwick , Victor Garcia
Published: October 2024

Cytochrome P450 fatty acid hydroxylase consists of members of the CYP4 family that ω-hydroxylate fatty acids and the CYP2E1 that ω-1 hydroxylates fatty acids. Although ω and ω-1 hydroxylation of fatty acids have been thought to play a minor role in fatty acid metabolism (less than 20%), it plays a vital role in excess liver fatty acids overload seen in fasting, diabetes, metabolic disorder, and over-consumption of alcohol and high-fat diet. This pathway provides anabolic metabolites for gluconeogenesis, succinate, and acetate for lipogenesis. The CYP4A and CYP2E1 genes are activated in fasting and several metabolic disorders, suggesting a synergistic role in preventing fatty acid-induced lipotoxicity with the consequence of increased liver cholesterol and lipogenesis leading to increased Lipid Droplet (LD) deposition. During the progression of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), activation of Phospholipase A2 (PLA2) releases arachidonic acid that CYP4A11 and CYP2E1 P450s metabolize to produce 20-hydroxyeicosatetraenoic acid (20-HETE) and 19-HETE, respectively. These metabolites have opposing roles in the progression of MASLD and chronic liver disease (CLD). This report discusses the synergistic role of the CYP4A and CYP2E1 P450s in the metabolism of saturated and unsaturated fatty acids and their opposite physiological role in the metabolism of Arachidonic Acid (AA). We finally discuss the role of ethanol in disrupting the synergistic and opposing roles of the CYP4A and CYP2E1 genes in MASLD and CLD.
Step-by-Step Protocol for Generating CRISPR-Mediated Knockout Cancer Cell Lines Using Transient Transfection v1
Authors: Alireza Mousavi Kahaki Seyed , Ebrahimzadeh Nayereh , Fahimi Hossein , Moshiri Arfa
Published: October 2024

The clustered regularly interspaced short palindromic repeats (CRISPR) system offers cost-effectiveness, high efficiency, precision, and ease of use compared to traditional gene editing techniques. In this study, we employed findings from prestigious investigations to develop an optimized approach for generating knockout cancer cell lines using a transient transfection method. This protocol introduces a distinctive approach that follows rigorous guidelines for designing gRNA to reduce off-target effects, a major challenge in CRISPR applications. Our step-by-step instructions allow researchers, particularly those with limited laboratory equipment and funding, as well as those undertaking CRISPR projects for the first time, to generate knockout cell lines using CRISPR technology in just ten weeks. This protocol covers all needs for enhancing various yields, such as transfection efficiency, and includes leveraging robust bioinformatics tools, conducting essential assays, isolating monoclonal cells via limiting dilution, validating knockout cells, and providing comprehensive troubleshooting recommendations. Using this method, we successfully created several new generations of colorectal cancer cell lines with monoallelic and biallelic knockouts of the epithelial cell adhesion molecule (EpCAM) gene. Our method, optimized for a wide spectrum of cancer cell lines, makes CRISPR more accessible for applications in personalized and precision medicine. It expands opportunities for novel investigations into cancer mechanisms and paves the way for potential therapeutic interventions.
Fuzzy Method for Preliminary Classification of the Micro-Electromechanical Systems Data
Authors:   Institute of Mathematics and Information Technology, Petrozavodsk State University, Petrozavodsk, 185910, Russian Federation, Bogoiavlenskaia O. Yu.
Published: October 2024

Data of micro-electromechanical systems (sensors) are widely used in modern multipurpose intellectual environments, autonomous mobile robots and automated systems possessing intellectual components. Since the amount of data delivered by the sensors is rather considerable and their significance varies we propose a fuzzy method of the data preliminary classification aimed at selection of the data important for the planning and control decisions while meaningless data or data that do not contain new information are discarded. As a result the amount of the resource intensive intellectual processing and the workload in the network infrastructure could be reduced significantly. The paper presents the analysis for the preliminary classification problem, the abstract model of a sensor and classification method. The method is based on the delay which is controlled by multiplicative decrease additive increase rule and expresses the expectation of the context uncertainty. The delay decreases if the variables measured by the sensor presumably change and increases if it keep its value. Numerical examples are presented as well. They consider the set of mount chest accelerometer uncalibrated measurements. We compare source data set and set of the selected values formed by an algorithm implementing fuzzy preliminary classification. Several metrics were used to compare the selected values with the source data and with CMA filter as well.