bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of mood in aphasia following stroke: validation of the Dynamic Visual Analogue Mood Scales (D-VAMS)
Authors: Barrows Paul D , Thomas Shirley A
Published: June 2017

Objectives:

To validate a non-verbal self-report measure of mood – the Dynamic Visual Analogue Mood Scales (D-VAMS) – against the Hospital Anxiety and Depression Scale (HADS) and assess its suitability as an outcome measure or screening measure for depressed mood following stroke.

Design:

Cross-sectional observational cohort study.

Participants:

Forty-six stroke survivors (24% with aphasia) recruited from online, from stroke clubs and via an NHS rehabilitation service.

Methods:

A set of seven bipolar scales was developed enabling users to report mood by modifying facial expression images using a slider. Participants completed a tablet/computer task, reporting their mood on these scales mixed randomly with versions which used only words. The HADS was then completed, followed by a repeat run of the two versions in a different, random sequence.

Results:

Exploratory factor analysis identified one factor consistent with pleasantness of mood accounting for 80% of the variance. Internal consistency of D-VAMS was high ( α = 0.95), and there was a high correlation between face-only D-VAMS scores and HADS total scores ( r = −0.80, P < 0.001), as well as HADS-D/HADS-A subscale scores ( r = −0.73, P < 0.001; r = −0.71, P < 0.001). D-VAMS showed good sensitivity and specificity against HADS, with means of 85%/77% (sensitivity/specificity) against the HADS-D and 80%/77% against the HADS-A across nine cut-offs.

Conclusion:

D-VAMS is a valid and reliable measure likely suitable for assessment of depressed mood in aphasia following stroke. Though D-VAMS performed well as a screening measure in this study sample, further study is needed in the acute stage post-stroke.
Racial-ethnic Identity Pairings and Mental Health of Second-generation Asian Adolescents
Authors: Vaghela Preeti , Ueno Koji
Published: June 2017

Second-generation adolescents experience identity conflict when trying to adapt to the United States. This identity conflict may be compounded for Asians, who experience racialization of their ethnicity. This intensity of identity conflict and racialization of ethnicity is reflected in different pairings of racial and ethnic identities (e.g., Hyphenated-Nationality, Hyphenated-Asian). We examine how these identity pairings are associated with mental health. Analysis used a sample of 1,308 second-generation Asian adolescents (aged 15–19) from the Children of Immigrants Longitudinal Study Wave 2 (1995–1996). Although not all associations were significant, low levels of identity conflict tended to be associated with lower levels of depression and more problem behaviors. Perhaps these identity pairings help reduce depression by lowering identity conflict while increasing peer conflicts. The analysis also showed that among adolescents with the same type of ethnic identity, mental health varied across racial identity, highlighting the importance of examining identity pairings.
Human Adolescent Phase Response Curves to Bright White Light
Authors: Crowley Stephanie J. , Eastman Charmane I.
Published: June 2017

Older adolescents are particularly vulnerable to circadian misalignment and sleep restriction, primarily due to early school start times. Light can shift the circadian system and could help attenuate circadian misalignment; however, a phase response curve (PRC) to determine the optimal time for receiving light and avoiding light is not available for adolescents. We constructed light PRCs for late pubertal to postpubertal adolescents aged 14 to 17 years. Participants completed 2 counterbalanced 5-day laboratory sessions after 8 or 9 days of scheduled sleep at home. Each session included phase assessments to measure the dim light melatonin onset (DLMO) before and after 3 days of free-running through an ultradian light-dark (wake-sleep) cycle (2 h dim [~20 lux] light, 2 h dark). In one session, intermittent bright white light (~5000 lux; four 20-min exposures) was alternated with 10 min of dim room light once per day for 3 consecutive days. The time of light varied among participants to cover the 24-h day. For each individual, the phase shift to bright light was corrected for the free-run derived from the other laboratory session with no bright light. One PRC showed phase shifts in response to light start time relative to the DLMO and another relative to home sleep. Phase delay shifts occurred around the hours corresponding to home bedtime. Phase advances occurred during the hours surrounding wake time and later in the afternoon. The transition from delays to advances occurred at the midpoint of home sleep. The adolescent PRCs presented here provide a valuable tool to time bright light in adolescents.
Hate Crimes Against Trans People: Assessing Emotions, Behaviors, and Attitudes Toward Criminal Justice Agencies
Authors: Walters Mark A. , Paterson Jennifer , Brown Rupert , McDonnell Liz
Published: June 2017

Based on a survey of 593 lesbian, gay, bisexual, and transgender (LGBT) people in the United Kingdom, this study shows that direct anti-LGBT hate crimes (measured by direct experiences of victimization) and indirect anti-LGBT hate crimes (measured by personally knowing other victims of hate crime) are highly prolific and frequent experiences for LGBT people. Our findings show that trans people are particularly susceptible to hate crimes, both in terms of prevalence and frequency. This article additionally highlights the negative emotional and (intended) behavioral reactions that were correlated with an imagined hate crime scenario, showing that trans people are more likely to experience heightened levels of threat, vulnerability, and anxiety compared with non-trans LGB people. The study found that trans people are also more likely to feel unsupported by family, friends, and society for being LGBT, which was correlated with the frequency of direct (verbal) abuse they had previously endured. The final part of this study explores trans people’s confidence levels in the Government, the police, and the Crown Prosecution Service (CPS) in relation to addressing hate crime. In general, trans people felt that the police are not effective at policing anti-LGBT hate crime, and they are not respectful toward them as victims; this was especially true where individuals had previous contact with the police. Respondents were also less confident in the CPS to prosecute anti-LGBT hate crimes, though the level of confidence was slightly higher when respondents had direct experience with the CPS. The empirical evidence presented here supports the assertion that all LGBT people, but particularly trans individuals, continue to be denied equal participation in society due to individual, social, and structural experiences of prejudice. The article concludes by arguing for a renewed policy focus that must address this issue as a public health problem.
Playing by the Rules: Agency Policy and Procedure in Service Experience of IPV Survivors
Authors: Wood Leila , Cook Heffron Laurie , Voyles Molly , Kulkarni Shanti
Published: June 2017

More than 1,800 programs exist in the United States, providing not only shelter but also transitional housing, advocacy and support, transportation, legal aid, and group and individual counseling for women who have experienced intimate partner violence (IPV). Shelter and transitional housing provide critical support for survivors, but have also been critiqued for having too many restrictive rules and code of conduct. More information is needed about the impact of rules and agency policy on women seeking services in IPV residential settings. This qualitative study explored the central research question, “How do rules shape IPV residential environment and survivor experiences in services?” Twenty-five women in four programs in two states who were currently residing in IPV residential services were interviewed about their experiences. Data were analyzed using grounded theory methods. Findings indicated rules affect individual survivors’ and families’ experiences and responses in services and of healing from IPV (micro), the relationships among residents and between residents and staff (mezzo), and participants’ relationships with the agency as an institution and the help-seeking community (macro). An intriguing paradox is noted in that at their best, rules provide stability and motivation for some survivors. At their worst, rules create isolation and force exit from shelter into unsafe circumstances, causing a ripple effect of impact. Implications include the need to restructure rules and policies collaboratively with residents, and reduce the amount of rules used in services. Addressing rules will better enable IPV services to be survivor-centered and trauma-informed, ultimately increasing safety and healing.
Gerrymandering and Malapportionment, Romanian Style: The 2008 Electoral System
Authors: Giugăl Aurelian , Johnston Ron , Chiru Mihail , Ciobanu Ionut , Gavriș Alexandru
Published: June 2017

Varieties of gerrymandering and malapportionment can appear not only in electoral systems where all legislative seats are allocated to plurality winners in single-member districts but also in proportional Single-Member District (SMD)–based electoral systems and in settings where multi-partisan committees draw the district boundaries. This article investigates such a case, in which the main parliamentary parties collaborated in order to minimize the uncertainty regarding intra-party allocation of seats. The 2008 electoral reform in Romania created such opportunities, and both the SMD maps and the electoral results at the parliamentary election held in the same year indicate that the parties collaborated to design a number of safe seats for each of them. We draw on a novel data set that measures the degree to which the newly created SMDs reflect natural or artificial strongholds of concentrated partisan support in otherwise unfavorable political territories, and also assess the malapportionment of these districts. All three types of mechanisms were frequently used, and our logistic regression analyses indicate that nomination from the “right” type of SMD was the main factor deciding which of each party’s candidates got elected. The statistical analyses are complemented by a qualitative investigation of the political composition and design of 9 SMDs.
An investigation into the use of a cyclone separator in the intake air system and its influence on the engine performance
Authors: Sakin Ali , Karagoz Irfan , Ergul Murat , Demirtas Unal , Savas Fatih Hakki
Published: June 2017

Filters are used to decontaminate the particles from the outside environment entering different subsystems of vehicles. Conventional air filters can cause a significant pressure drop in the intake air system because of their porous structure. In this study, a cyclone separator was designed and manufactured for the air intake system of an automobile. The pressure drop and the performance parameters of the engine were measured by using a conventional air filter or a cyclone separator in the air intake system. Futhermore, a computational fluid dynamics analysis of the cyclone separator was performed, and the results were compared with the experimental data.
Bioinformatics methods for identifying differentially expressed genes and signaling pathways in nano-silica stimulated macrophages
Authors: Zhang Lin , Hao Changfu , Li Juan , Qu Yaqian , Bao Lei , Li Yiping , Yue Zhongzheng , Zhang Miao , Yu Xinghao , Chen Huiting , Zhang Jianhui , Wang Di , Yao Wu
Published: June 2017

The incidence of disease relating to nanoparticle exposure has been rising rapidly in recent years, for which there is no effective treatment. Macrophage is suggested to play a crucial role in the development of pulmonary disease. To investigate the changes in macrophage after being stimulated by nanometer silica dust and to explore potential biomarkers and signaling pathways, the gene chip GSE13005 was downloaded from Gene Expression Omnibus database, which contained 21 samples: 3 samples per group and 7 groups in total. Macrophages in the control group were cultured in serum-free medium, while the experimental groups were treated with nanometer silica dust in different sizes and concentrations, respectively. To identify the differentially expressed genes and explore their potential functions, we adopted the gene ontology analysis and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis and also constructed protein–protein interaction network. As a result, 1972 differentially expressed genes were identified from 22,690 microarray data in the gene chip, 1069 genes were upregulated and 903 genes were downregulated. Results of the gene ontology analysis indicated that the differentially expressed genes were widely distributed in intracellular and extracellular regions, regulating macrophage apoptosis, inflammatory response, and cell differentiation. The Kyoto Encyclopedia of Genes and Genomes pathway analysis showed that the majority of differentially expressed genes were enriched in cytokine–cytokine receptor interaction, cancer or phagosome transcriptional misregulation. The top 10 hub genes, S100a9, Nos3, Psmd14, Psmd4, Lck, Atp6v1h, Jun, Foxh1, Pex14, and Fadd were identified from protein–protein interaction network. In addition, Nos3, Psmd14, Atp6v1h, and Jun were clustered into module M2 (rc = 0.74, p < 0.01), which mainly regulates cell carcinogenesis and antivirus process. In conclusion, differentially expressed genes screened from this study may provide new insights into the exploration of mechanisms, biomarkers, and therapeutic targets for diseases relating to nanoparticle exposure.
Accessible Media: The Need to Prepare Students for Creating Accessible Content
Authors: Youngblood Norman E. , Tirumala Lakshmi N. , Galvez Robert Anthony
Published: June 2017

Electronic media accessibility has come a long way since the Telecommunications Act of 1996. In 2010, the Communication and Video Accessibility Act (CVAA) mandated closed captioning many online videos and called for making video blind accessible through audio descriptions. The Department of Justice (DOJ) ruled Americans With Disabilities Act (ADA) applied to the virtual world. Since January 2015, there have been over 240 online-accessibility lawsuits. As educators, we need to prepare students to understand what accessibility is and how to make electronic media accessible. This article outlines accessibility issues across the curriculum, including closed captioning, audio descriptions, and online documents, and calls for better integration of accessibility into the electronic media curriculum.
Coupled wind-induced responses and equivalent static wind loads on long-span roof structures with the consistent load–response–correlation method
Authors: Luo Nan , Jia Hongyu , Liao Haili
Published: June 2017

Long-span roof structures with multiple vibration modes may undergo coupled motions when exposed to spatiotemporally varying dynamic wind loads. This article presents a framework for the analysis of coupled wind-induced responses and equivalent static wind loads on long-span roof structures. This framework takes into account the inter-modal coupling of modal response components and cross correlation between the background and resonance. The load–response–correlation method is widely used for the background equivalent static wind loads of rigid structures. Also, the concept of load–response–correlation was extended for the correct estimation of equivalent static wind loads by considering the correlation between the load and exact total responses. However, there is no detailed study for the correct estimation of equivalent static wind loads on the component of background, resonance, and their cross response using load–response–correlation method. In this article, a consistent load–response–correlation method for equivalent static wind loads is presented in a unified framework which contains the background, resonance, and modal coupling. First, the accuracy of wind-induced responses is ensured by considering the modal coupling. Meanwhile, the efficiency is improved by decomposing the covariance matrix of the generalized resuming forces. Second, several effects of the wind-induced responses are discussed in detail, such as the effect of the modal coupling, the effect of the modal participations to resonant responses, and the effect of the cross correlation between the background and resonance. Finally, the proposed equivalent static wind loads are represented by the composition of the external wind loads and inertial forces, which are both the most probable load distributions. Accordingly, the equivalent static wind load distribution and the responses by equivalent static wind loads are reasonable.
Journalists at a crossroads: Are traditional norms and practices challenged by Twitter?
Authors: Bentivegna Sara , Marchetti Rita
Published: June 2017

This article aims to identify the hybridization that journalists have created to reconcile the pressures arising from the affirmation of the culture of participation and sharing of social media with the traditional norms and practices that are the basis of the journalistic identity. This study analyses the behavior of 1202 Italian journalists on Twitter between 1 January and 29 February 2016, focusing on the interpretation of the transparency norm, the gatekeeping function, and audience engagement. These are norms and practices that are both old and new and that allow us to understand the adaptations journalists make in order to respond to the technological transformations that have affected existing models of journalism and the degree of professionalization of journalists themselves. Through the analysis of the 23,515 tweets published by journalists of different media outlets (newspapers, wire services, TV news, and only-online media), this study has allowed to empirically test the existence of a general adoption of Twitter by Italian journalists, characterized by a ‘hybrid normalization’, that is, a combination of old practices with new modalities with the dual aim of sharing the culture of social media and legitimizing the professional position of journalism.
How right-wing versus cosmopolitan political actors mobilize and translate images of immigrants in transnational contexts
Authors: Doerr Nicole
Published: June 2017

This article examines visual posters and symbols constructed and circulated transnationally by various political actors to mobilize contentious politics on the issues of immigration and citizenship. Following right-wing mobilizations focusing on the Syrian refugee crisis, immigration has become one of the most contentious political issues in Western Europe. Right-wing populist political parties have used provocative visual posters depicting immigrants or refugees as ‘criminal foreigners’ or a ‘threat to the nation’, in some countries and contexts conflating the image of the immigrant with that of the Islamist terrorist. This article explores the transnational dynamics of visual mobilization by comparing the translation of right-wing nationalist with left-wing, cosmopolitan visual campaigns on the issue of immigration in Western Europe. The author first traces the crosscultural translation and sharing of an anti-immigrant poster created by the Swiss People’s Party (SVP), a right-wing political party, inspiring different extremist as well as populist right-wing parties and grassroots activists in several other European countries. She then explores how left-libertarian social movements try to break racist stereotypes of immigrants. While right-wing political activists create a shared stereotypical image of immigrants as foes of an imaginary ethnonationalist citizenship, left-wing counter-images construct a more complex and nuanced imagery of citizenship and cultural diversity in Europe. The findings show the challenges of progressive activists’ attempts to translate cosmopolitan images of citizenship across different national and linguistic contexts in contrast to the right wing’s rapid and effective instrumentalizing and translating of denigrating images of minorities in different contexts.
Impedance-based damage detection under noise and vibration effects
Authors: Campeiro Leandro M , da Silveira Ricardo ZM , Baptista Fabricio G
Published: June 2017

The electro-mechanical impedance technique has been extensively studied in recent decades as a non-destructive method for detecting structural damage in structural health monitoring applications using low-cost piezoelectric transducers. Although many studies have reported the effectiveness of this detection method, numerous practical problems, such as the effects of noise and vibration, need to be addressed to enable this method’s effective use in real applications. Therefore, this article presents an experimental analysis of noise and vibration effects on structural damage detection in impedance-based structural health monitoring systems. The experiments were performed on an aluminum bar using two piezoelectric diaphragms, where one diaphragm was used to measure the electrical impedance signatures and the other diaphragm was used as an actuator to generate noise and controlled vibration. The effects of noise and vibration on impedance signatures were evaluated by computing the coherence function and basic damage indices. The results indicate that vibration and noise significantly affect the threshold of the lowest detectable damage, which can be compensated by increasing the excitation signal of the piezoelectric transducer.
Rapid liver and spleen stiffness improvement in compensated advanced chronic liver disease patients treated with oral antivirals
Authors: Pons Mònica , Santos Begoña , Simón-Talero Macarena , Ventura-Cots Meritxell , Riveiro-Barciela Mar , Esteban Rafael , Augustin Salvador , Genescà Joan
Published: June 2017

Background

We aimed to investigate the early changes in liver and spleen stiffness measurement (LSM, SSM) in hepatitis C virus (HCV) patients with compensated advanced chronic liver disease (cACLD) treated with new antivirals (DAA) to elucidate factors determining the initial change in stiffness and its implications for the long-term follow up of HCV-cured patients.

Methods:

A total of 41 patients with cACLD who started DAA therapy underwent LSM and SSM at baseline, week 4, end of treatment (EOT), 24 and 48 weeks of follow up using transient elastography.

Results:

LSM improved rapidly during the first 4 weeks of treatment (baseline: 20.8kPa; week 4: 17.5kPa, p = 0.002), with no significant changes between week 4 and EOT (18.3kPa, p = 0.444) and between EOT and 48-week follow up (14.3kPa, p = 0.148). Likewise, SSM improved rapidly (baseline: 45.7kPa; week 4: 33.8kPa, p = 0.047), with no significant changes between week 4 and EOT (30.8kPa, p = 0.153) and between EOT and 48-week follow up (31.2kPa, p = 0.317). A higher decrease in LSM was observed in patients with baseline ALT ⩾ twofold upper limit normal (2 × ULN) than in those with ALT < 2 × ULN (–5.7kPa versus –1.6kPa). Patients who presented a decrease in LSM ⩾ 10% during treatment compared with those with LSM < 10% decrease, showed lower SSM values, higher platelet counts and lower bilirubin levels at 24-week follow up. Those with decrease in SSM ⩾ 10%, presented a higher increase in platelets than those with SSM < 10% change ( p = 0.015).

Conclusions:

LSM and SSM decrease very rapidly during DAA treatment in cACLD patients suggesting that it most probably reflects a reduction in inflammation rather than in fibrosis. cACLD patients should be maintained under surveillance independently of stiffness changes, because advanced fibrosis can still be present.
Blake’s pouch cyst in children: Atypical clinical presentation
Authors: Bontognali Martina , Poretti Andrea , Guzman Raphael , Huisman Thierry AGM , Ramelli Gian Paolo
Published: June 2017

Blake’s pouch cyst is a posterior fossa cystic malformation characterized by a infracerebellar cyst, absence of communication between the fourth ventricle and the subarachnoid space, and tetraventricular hydrocephalus. Children with Blake’s pouch cyst typically present with macrocephaly due to hydrocephalus during the neonatal period or infancy. Atypical presentation is, however, possible. Here we present clinical and neuroimaging findings, as well as management and outcome, of an 18-month-old girl with atypical presentation of Blake’s pouch cyst characterized by cerebellar ataxia. Familiarity with the neuroimaging findings of Blake’s pouch cyst and differentiation between Blake’s pouch cyst and other posterior fossa cystic malformations is important in terms of diagnosis, management, prognosis, and counseling of the affected families.
Integrating and safeguarding care: The potential role of health information technologies
Authors: Desmedt Melissa , Pless Sam , Dessers Ezra , Vandijck Dominique
Published: June 2017

The increasing burden of chronic diseases is one of the greatest challenges healthcare systems globally are facing. Across the world, compelling demands can be found for a fundamental shift in the organisation of health and social care to meet the needs of chronic patients. Integrated care has gathered momentum to overcome fragmentation of care in order to create care systems which are demand-driven, client-centred and cost-conscious. Health information technology – often referred to as eHealth – is usually considered to be an essential building brick of integrated care. Moreover, health information technology is said to hold potential for improving patient safety in chronic care settings. The current perspective paper explores the role of health information technology in integrating and safeguarding care. We argue that health information technology – which supports integrated care – may create optimal conditions to improve patient safety, but only when well-implemented, state-of-the-art technologies are used.
Acceptability and willingness to pay for telemedicine services in Enugu state, southeast Nigeria
Authors: Arize Ifeyinwa , Onwujekwe Obinna
Published: June 2017

Background

This study examines the level of awareness, acceptability and consumers’ willingness to pay (WTP) for telemedicine services using the contingent valuation method (CVM). This work is important as it elicits the value that consumers attach to telemedicine given there is a gap in this knowledge in many sub-Saharan countries such as in Nigeria.

Methods

The study was based on primary data obtained through an interviewer-administered questionnaire of 370 individuals including both males and females from 25 years and over, to collect data on respondents’ awareness of, acceptability of, and WTP for telemedicine, using the bidding game question format. A socioeconomic status (SES) index was created, based on information on household assets, and was used to categorize respondents into SES quartiles. The data were analyzed using a combination of descriptive techniques, logistics and the Tobit regression model (Tobit Type 1) methods.

Results

The study found that majority of the people (58.9%) had no knowledge of telemedicine. However, 48.7% of the respondents were willing to pay for telemedicine. The mean WTP for a telemedicine was US$2.04 for each visit. Tobit regression analysis showed that respondents’ socioeconomic status (SES) was the main statistically significant variable that explained their WTP for telemedicine.

Conclusion

The study has shown that there is a low-level awareness of and WTP for telemedicine services in Enugu State, South East of Nigeria. The finding of a positive relationship between SES and WTP implies that the poor may not be able to pay for telemedicine and may need government subsidies to be able to benefit from such service. Also, government and their partners need to undertake wide scale campaign before the introduction of telemedicine.
Low-Fat Dietary Pattern and Breast Cancer Mortality in the Women’s Health Initiative Randomized Controlled Trial
Authors: Chlebowski Rowan T. , Aragaki Aaron K. , Anderson Garnet L. , Thomson Cynthia A. , Manson JoAnn E. , Simon Michael S. , Howard Barbara V. , Rohan Thomas E. , Snetselar Linda , Lane Dorothy , Barrington Wendy , Vitolins Mara Z. , Womack Catherine , Qi Lihong , Hou Lifang , Thomas Fridtjof , Prentice Ross L.
Published: June 2017

Purpose

Earlier Women’s Health Initiative Dietary Modification trial findings suggested that a low-fat eating pattern may reduce breast cancers with greater mortality. Therefore, as a primary outcome-related analysis from a randomized prevention trial, we examined the long-term influence of this intervention on deaths as a result of and after breast cancer during 8.5 years (median) of dietary intervention and cumulatively for all breast cancers diagnosed during 16.1 years (median) of follow-up.

Patients and Methods

The trial randomly assigned 48,835 postmenopausal women with normal mammograms and without prior breast cancer from 1993 to 1998 at 40 US clinical centers to a dietary intervention with goals of a reduction of fat intake to 20% of energy and an increased intake of fruits, vegetables, and grains (40%; n = 19,541) or to a usual diet comparison (60%; n = 29,294).

Results

In the dietary group, fat intake and body weight decreased (all P < .001). During the 8.5-year dietary intervention, with 1,764 incident breast cancers, fewer deaths occurred as a result of breast cancer in the dietary group, which was not statistically significant (27 deaths [0.016% per year] v 61 deaths [0.024% per year]; hazard ratio [HR], 0.67; 95% CI, 0.43 to 1.06; P = .08). During the same period, deaths after breast cancer (n = 134) were significantly reduced (40 deaths [0.025% per year] v 94 deaths [0.038% per year]; HR, 0.65; 95% CI, 0.45 to 0.94; P = .02) by the dietary intervention. During the 16.1-year follow-up, with 3,030 incident breast cancers, deaths after breast cancer also were significantly reduced (234 deaths [0.085% per year] v 443 deaths [0.11% per year]; HR, 0.82; 95% CI, 0.70 to 0.96; P = .01) in the dietary group.

Conclusion

Compared with a usual diet comparison group, a low-fat dietary pattern led to a lower incidence of deaths after breast cancer.
Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics
Authors: Koehorst Jasper J. , Saccenti Edoardo , Schaap Peter J. , Martins dos Santos Vitor A. P. , Suarez-Diez Maria
Published: June 2017

A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for defining arbitrary acceptance thresholds for similarity and alignment length, lateral gene acquisition and the high computational cost for finding bi-directional best matches at a large scale. We investigated the use of protein domain architectures for large scale functional comparative analysis as an alternative method. The performance of both approaches was assessed through functional comparison of 446 bacterial genomes sampled at different taxonomic levels. We show that protein domain architectures provide a fast and efficient alternative to methods based on sequence similarity to identify groups of functionally equivalent proteins within and across taxonomic boundaries, and it is suitable for large scale comparative analysis. Running both methods in parallel pinpoints potential functional adaptations that may add to bacterial fitness.
Actual Problems of Professional Self-Determination of Upper-Form Pupils
Authors: Высоцкий  , Vysockiy V.
Published: June 2017

The article discusses the issues of assistance in professional self-determination of upper-form pupils. The problems existing in education and society are described. A positive world experience of promoting the professional choice of students is indicated. The importance of systemic organization of this with the involvement of all subjects work is emphasized: the state, state educational organizations and social protection organizations, as well as non-governmental organizations, the family and the student himself. There is an inadequate participation of the state in the process. The importance of strengthening its role is explained. The author offers solutions to the existing problems of professional self-determination of upper-form pupils.
Chromato-mass-spectrometry of alcohol extraction of huminic acid of sapropel of azov floodplain of Krasnodar region
Authors: Хадарцев  , Khadartsev A. , Платонов  , Platonov V. , Белозерова  , Belozerova L.
Published: June 2017

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Clinical experience of the use emollients for prevention of exacerbations of chronic allergic dermatoses in workers of metallurgical production
Authors: Моисеева  , Moiseeva I. , Бережнова  , Berezhnova T.
Published: June 2017

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Evaluation of the diagnostic effectiveness of the new express-test for cardiac protein, binding fatty acids
Authors: Кокорин  , Kokorin V. , Гончаров  , Goncharov A. , Яковцова  , Yakovcova A. , Гончарова  , Goncharova A.
Published: June 2017

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Cognitive activity of the students and its haemodynamic ensuring
Authors: Андрианов  , Andrianov V
Published: June 2017

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The impact of microwave electromagnetic field on microbes
Authors: Ихлов  , Ihlov B.
Published: June 2017

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RESEARCH OF PERSONNEL POLICY OF THE ENTERPRISE (ON THE EXAMPLE OF OAO URALMEKHANOBR)
Authors: Глухенькая  , Glukhenkaya N. , Денисьева  , Denis'eva A.
Published: June 2017

The article discusses the concept of personnel policy of the organization. The analysis of the staffing policy of the leading specialists of our country: Kibanov A.Ya., Egorshin A.P., etc. is given. The authors investigated the personnel policy of the enterprise OAO Uralmekhanobr. The following policies are reviewed and analyzed: recruitment and selection of staff, training of staff, and motivation of staff. For the analysis of personnel policy Uralmekhanobr OAO the following methods were used: analysis of scientific literature, analysis of documents of the enterprise, the conversation with the user, the test Martin – Richie, ranking of test results. The article presents ten documents of the organization. Among them there are the “Staff regulations”, “Regulations on remuneration of personnel”, “Regulations on hiring, movement and termination of personnel”, “Regulations on the promotion of scientific activities of employees of OAO Uralmekhanobr and others. On the base of results of the research personnel policy the conclusions are made. The management personnel of the enterprise has “active” recruitment policy. It is aimed at the development of the main directions of personnel policy: personnel training, recruitment and selection of personnel, motivation of the personnel.
MODERN PROBLEMS OF PREPARATION AND RETRAINING OF PERSONNEL FOR SMALL BUSINESSES
Authors: Свистунов  , Svistunov Vasiliy , Лобачев  , Lobachyev Vitaliy , Алешина  , Aleshina A.
Published: June 2017

This article analyzes the current characteristics of the training and retraining of personnel for small businesses. In times of crisis survive the organizations that managed to capture trend changes and quickly adapt to them, including through development of its strategy of work with personnel. In this regard, of practical interest are current directions of personnel work of small businesses. Analysis of practical results in this direction in the work of small businesses suggests that today, the domestic organization is often inefficient to implement in practice. This gives grounds to speak about the need to improve work with the staff of small business organizations.
Analysis and classification of engineering parts
Authors: Базров Борис , Bazrov Boris
Published: June 2017

A possibility of product classifications for mechanical engineering development is shown. General classifications of ma-chines and engineering products are considered. The absence of a single methodical approach in classifications formation is emphasized.
Strategic Management: A Textbook for Universities
Authors: Егоршин  , YEgorshin Alyeksandr , Гуськова  , Guskova Irina
Published: June 2017

In the textbook the fundamentals of strategic management, the methods of diagnostic analysis and strategic planning, the development of competition strategies and the management of strategy implementation at enterprises and organizations in a concise, concentrated form are examined. Development of competition strategies and management of strategy implementation at enterprises and organizations. The novelty of the textbook is the use of methods of diagnostic analysis and forecasting of the organization's activities, expert modeling of problems and competition strategies, rationalization of the management system and management of changes in the organization in a crisis and post-crisis in Russia.
Conflicto de intereses en el contexto societario: regulación colombiana y derecho comparado
Authors: Arcila Salazar Carlos Andrés
Published: June 2017

Este documento tiene como propósito ilustrar sobre la regulación colombiana en relación con el conflicto de intereses en el contexto societario, de la mano de la doctrina nacional, y el derecho comparado, para entender las actuales discusiones en esta materia y ver hacia dónde debe enfocarse el análisis de las futuras reformas legislativas.
A Reinterpretation of the Optimal Demand for Risky Assets in Fund Separation Theorems
Authors: Deguest Romain , Martellini Lionel , Milhau Vincent
Published: June 2017

In a continuous-time portfolio selection model with N risky assets and K state variables driving their risk and return parameters, we derive simple expressions for the allocation to each asset in the K + 1 risky funds of the (K + 2)-fund separation theorem. We show that the allocation to any given risky asset in each fund can be written in terms of the parameters of a regression of the excess returns of this asset on those of the N − 1 remaining assets. We also use these parameters to provide quantitative measures of the increase in Sharpe ratio of the speculative demand, or in the maximum correlation of each hedging demand with respect to the corresponding risk factor, associated with the introduction of a new asset in the investment universe. Finally, we show that in a multiperiod setting, an asset is “spanned” by others if and only if it improves neither the maximum Sharpe ratio of the speculative demand nor the maximum correlations of the hedging demands with the risk factors.

This paper was accepted by Lauren Cohen, finance.
Pain scoring systems in the canine and feline patient
Authors: Bloor Claire , Allan Lorraine
Published: June 2017

It is important that veterinary professionals are able to recognise and assess pain in patients under their care. Veterinary patients cannot verbalise, or self-report on the amount of pain they are experiencing, so it is the responsibility of the professionals caring for them to be able to recognise the signs of pain, which can differ greatly between species. Once the veterinary professional has recognised the signs of pain during assessment they can then determine and appreciate the type or types of pain the patient is suffering, for example neuropathic, acute and chronic, and create an individual analgesic treatment plan. The assessment of pain in animals is for the most part based on the recognition of behavioural changes in response to pain, which cannot only vary between species but also between individuals within that species. Pain scoring systems can be utilised to quantify pain; putting a number on the level of pain for the purpose of determining whether pain exists, whether analgesia is sufficient, and in order to monitor patient progress in terms of pain management. These take into account the behavioural changes and responses of the patient and guide the user towards the calculation of a score. This article explores some of the key concepts relating to the recognition and quantification of pain, and the reliability and validity of pain scores, before considering the different pain scoring systems available for use in veterinary practice and their relative merits.
A patient care report of a feline with newly diagnosed diabetes mellitus hospitalised for a blood glucose curve
Authors: Paskeviciute Justina
Published: June 2017

Feline diabetes mellitus is one of the most common endocrine disorders in cats. Veterinary nurses play a huge role in management of these feline patients by helping with diagnostics, monitoring blood glucose levels, administering medication, providing skilled nursing care during the time of hospitalisation as well as educating and advising the clients. This patient care report discusses the care provided to a diabetic feline patient that was hospitalised for a blood glucose curve.
Building an Alliance: A new future for academic dentistry ‘Down Under’?
Authors: Thomson Peter
Published: June 2017

A leap of faith took Peter Thomson from years of service in the NHS to an Oral Health Alliance ‘down under’. Here, he talks about oral health and the organisation of dental services in Australia, as well as the drivers of change in academic dentistry that led to the formation of the Alliance between the University and a large public healthcare provider to deliver excellence in teaching, research and clinical practice.
Propuesta de creación de una microrreserva en el Peñón de Salobreña para la protección de los hábitats del litoral de Granada (España)
Authors: Gómez-Zotano José , Olmedo-Cobo Jose Antonio , Martínez-Ibarra Emilio
Published: June 2017

Se propone la creación de una microrreserva de flora en el litoral de la provincia de Granada (Andalucía, sur de España). Esta figura de protección es un modelo pionero de conservación en enclaves de elevada fitodiversidad, no incluidos en la Red de Espacios Naturales Protegidos de Andalucía [RENPA]. La franja litoral de Granada ha experimentado un continuo proceso de ocupación durante las últimas décadas como consecuencia del turismo y la agricultura, por lo que se ha producido la degradación de ecosistemas costeros frágiles y dinámicos. El trabajo de campo ha sido el principal procedimiento metodológico para llevar a cabo la investigación, dada la falta de estudios sobre conservación de hábitats en la costa de Granada. Se ha tomado como punto de partida la localización de los taxones más amenazados y los hábitats naturales de interés comunitario de la Red Natura 2000. A continuación, se ha analizado un caso práctico, el Peñón de Salobreña, como modelo de microrreserva vegetal y área piloto para la conservación y posible regeneración de hábitats litorales. Se ha llegado a la conclusión de que este modelo de protección in situ es ideal para la gestión de pequeñas áreas de alto valor ecológico en regiones tan degradadas y humanizadas como el litoral mediterráneo andaluz.
Diseño y aplicación en SIG de un indicador de obstrucción al escurrimiento superficial en planicies aluviales reguladas: el caso del Río Neuquén (Argentina)
Authors: Bosisio Andrea Cecilia
Published: June 2017

La construcción de presas y embalses en una planicie de inundación fluvial ocasiona modificaciones al funcionamiento natural de este sistema, regulando la erogación de caudales. Uno de los principales efectos inmediatos de esta situación es la ocupación antrópica no planificada, con la consiguiente alteración positiva o negativa, de las variables ambientales, y específicamente de los usos del suelo dentro de la planicie.La evaluación de estos cambios resulta entonces una prioridad para lograr un conocimiento más objetivo de sus consecuencias. En esta aportación se aborda la construcción de un indicador del grado de obstrucción al escurrimiento superficial, aplicándolo en un tramo del río Neuquén (Argentina), el cual se ubica aguas abajo de la presa Portezuelo Grande hasta el embalse San Patricio del Chañar; como resultado relevante se ha producido una cartografía final que destaca las zonas problemáticas. Con ello se busca analizar implicancias y avanzar hacia una herramienta idónea de diagnóstico de posibles cambios ambientales que deriven en situaciones de vulnerabilidad hídrica, y que deban ser considerados en futuros planes de manejo del tramo en cuestión.
Reseña de Turismo y crisis, turismo colaborativo y ecoturismo
Authors: Roig i Munar Francesc Xavier
Published: June 2017

El futuro del modelo turístico Baleares se ha convertido en los últimos años en un debate público. El incremento del número de turistas, el progresivo nivel de concienciación de la sociedad hacia la saturación del espacio, y las modificaciones legislativas sobre las tipologías de turismo ha generado debate en foros académicos, mediáticos, políticos e incluso en la sociedad. Los efectos positivos de la actividad turística en la economía de Baleares y en su mercado laboral son evidentes. El turismo sigue siendo el motor de la economía en las comunidades litorales mediterráneas del estado español. También es un hecho que el modelo de crecimiento de las últimas décadas, centrado en exceso en la reproducción del turismo de masas, demonimido “balearización” y exportado otros continentes, ha provocado a la larga una pérdida relativa de bienestar económico y social, aumentando la percepción de saturación, y surgiendo la duda que en los próximos años se pueda superar la capacidad de carga que los recursos pueden tolerar.
Sumario
Authors: Editor Editor
Published: June 2017

Sumario
Papeles de investigación: Imaginación crítica de Nicolás Rosa
Authors: Hidalgo Nácher Max
Published: June 2017

Nicolás Rosa fue un agente importante en la renovación de los estudios literarios en Argentina desde la segunda mitad de los años sesenta. Coincidiendo con el décimo aniversario de su muerte, este escrito propone una primera aproximación a su concepción de la literatura, su recorrido crítico y sus autofiguraciones. Para hacerlo, además de establecer las vías críticas fundamentales desarrolladas por Rosa, reconstruye algunas de las líneas mayores de la historia de la recepción y los usos de la teoría literaria francesa en Argentina.
Papeles de investigación: La piedra y el poema. Materiales para una memoria poética desobrada
Authors: Billi Noelia , Fleisner Paula
Published: June 2017

A propósito de El sexo de las piedras, de Fernando Araldi Oesterheld, nos proponemos pensar la poesía como un modo de ejercicio de la memoria que ya no puede ser escrita y archivada para su conservación en un contenido definitivo. La máquina poética abre a otra dimensión de la memoria en donde es posible hacer jugar lo inolvidable sin reducirlo a lo memorable, pues el poeta se mueve siempre en la tensión entre el recuerdo de lo que quiere olvidar y el olvido de lo que busca recordar. Así pues, la imagen poética apuntaría a conformar una presencia espectral que, lejos de la individualización de los contenidos de la memoria, circula transformándose y transformando el mundo en su contacto. En este sentido, la opera prima de Araldi Oesterheld nos ofrece la presencia imposible de sus padres (desaparecidos durante el terrorismo de Estado de la última dictadura cívico–militar) a través de imágenes que, al decir de Blanchot, restituyen su «realidad de tierra», su «materia–emoción».
Dossier Fin y resistencia de la teoría: La tentación de la inteligencia. Paul de Man lee a Roland Barthes.
Authors: Podlubne Judith
Published: June 2017

Cuando tuvo lugar el simposio de Baltimore, «Los lenguajes críticos y las ciencias del hombre. Controversia estructuralista», Paul De Man era ya un especialista en romanticismo y posromanticismo francés, inglés y alemán, aunque no tenía aún ningún libro publicado. Roland Barthes, en cambio, acababa de publicar Crítica y verdad y su figura había alcanzado una notoriedad pública inusitada. De Man lo leía desde de El grado cero de la escritura (1953); había escrito sobre ese libro y Michelet. Es probable que las circunstancias no fueran recíprocas y que Barthes no supiera quién era De Man. El encuentro entre ambos resultó destemplado, debido a las objeciones que De Man le dirigió en el debate posterior a la lectura de «Escribir, verbo intransitivo». El artículo analiza el intercambio inicial, para examinar luego el ensayo «Roland Barthes and Limits of Structuralism», que De Man escribió en 1972. El propósito es mostrar cómo las lecturas de De Man ofrecen pruebas diferidas o manifiestas de resistencia teórica a las postulaciones de Barthes.