bluuebunny/crossref_metadata_2025 huggingface dataset:
METHODS OF MASTERING THE SKILLS OF VISUAL EXPRESSION OF STUDENTS IN THE PROCESS OF WORKING ON STILL LIFE
Authors:   PhD Student, Namangan State University, Uzbekistan, Umataliyev Mukhtarjon A.
Published: June 2024

The purpose of this article is to introduce students to the genre of still life, to define concepts such as “method”, “painting”, “still life painting”, “painting”, “painting technique”, “technique of working with painting materials” and based on them, the technique of working with painting materials dedicated to clarifying the important methods and ways to master in the example of still life painting.
PREPOSITIONAL CONSTRUCTIONS IN THE SENTENCE
Authors:   Teacher of foreign languages, Karshi Engineering Economics Institute, Uzbekistan, Urinovich Jumanazarov Samandar
Published: June 2024

This article describes “A phrasal verb is a combination of a verb and one or more prepositions plus possible other words in addition. The article presents theoretical ideas in this regard and proves them with examples.
TESTING OF NEW MODERN DRUGS AGAINST ECTOPARASITES OF KARAKUL SHEEP
Authors:   Assistant, Samarkand State University of Veterinary Medicine, livestock and biotechnology, Uzbekistan, Jabborov G.G. , Raimkulov I.X. ,   Assistant, Samarkand State University of Veterinary Medicine, livestock and biotechnology, Uzbekistan, Sobirov O.O. ,   Samarkand State University of Veterinary Medicine, livestock and biotechnology,Uzbekistan
Published: June 2024

The article presents pathogens, epizootological data, course and symptoms of sheep psoroptosis. The results of the use of the antiparasitic drug ivermectin - 10 in sheep psoroptosis are also presented. Pathogens, epizootological data, course and symptoms of sheep psoroptosis are given in the article. And also provides the results of the use of an antiparasitic drug - ivermectin - 10 with sheep psoroptosis.
Key Issues and Processes Pertinent to the Management of Conventional Ammunition: Report of the Second Thematic Seminar
Authors: Shiotani Himayu , Bevan James , Martinez Miralles Manuel , Wilkin Sebastian
Published: June 2024

This publication presents the conclusions of UNIDIR 's Project on Framing and Informing Key Issues and Processes Relevant to the Management of Conventional Ammunition. The seminar took place on 26-27 November 2018 in Geneva, Switzerland This Project aims to Facilitate dialogue and generate insights to support and help States frame key issues and inform them about processes relating to WAM that progress can be made at the national, regional and multilateral levels. Elements and Findings from this seminar series are subject to States' preparations for the open, informal consultations Organized Within the framework of resolution 72/55, and other relevant conventional ammunition management initiatives.
The Effect of Enterobiasis Prevention Education on the Level of Knowledge of Students
Authors: Putri Fransisca Dian Nathania , Nugraheni Pramita Anindya , Risma Risma
Published: June 2024

Enterobiasis is a disease caused by the parasitic worm Enterobius vermicularis. This disease often occurs in children aged 5-14 years. Enterobiasis is a disease that can cause symptoms, one of which is itching in the perianal area. This can cause sleep disorders so that a child's concentration can be disturbed and of course this will affect the child's learning ability, as well as impacting the quality of a generation. This study aims to determine the effect of health education on the level of knowledge of elementary school students in grades 4-6 at SDN Kaliasin 1 Surabaya regarding the prevention of enterobiasis. This research is an observational analytical study with a cross sectional design and uses primary data in the form of a questionnaire. The method used in this research is a quantitative method. The research results showed that before health education, respondents with a good level of knowledge were 24.7%, 48.1% were adequate, and 27.2% were poor, whereas after health education the results obtained were respondents with a good level of knowledge of 64.2%, 24.7% sufficient, and less by 11.1%. Based on the results of the paired Wilcoxon test, the p value was 0.000, which means the p value <0.005, so it can be concluded that there is an influence of health education on the level of knowledge of elementary school students in grades 4-6 at SDN Kaliasin 1 Surabaya on the prevention of enterobiasis.
Relationship between Nutritional Status and Postoperative Outcomes of Breast Cancer
Authors: Ismawardany Imran Andi , Bamahary Aryanti R. , Pratama Ahmad Ardhani , Purnamasari Reeny , Latief M Shofiyah , Sakti Dachlia Sri
Published: June 2024

Breast cancer is the most common cancer in the world which is expected to increase morbidity and mortality rates . Nutritional status is an indicators that can be used to predict post-operative breast cancer outcomes . Breast cancer patients with poor / more nutritional status has a higher risk of experiencing more post-operative complications . This study was conducted to determine the nutritional status with post-operative outcomes in breasts Cancer patients. To determine the relationships between nutritional status (BMI) and post-operative outcomes in breast cancer patients at the Ibnu Sina Hospital Makassar. This study is cross -sectional analytic study, using a total sampling method with a total of 55 samples from patients medical records . Data analysis used the Chi- square test to assess whether there was a relationship. Obtained a significant relationships between nutritional status and length of stay (p = 0.002), and lymphedema (p = 0.027). While the relationships between nutritional status and post-operative wound complications was obtained (p = 0.052), .” history (p = 0.171). There is a relationships between nutritional status and post-operative outcomes for breasts Cancer.
Metabolic Reprogramming in Thyroid Cancer
Authors: Ju Sang-Hyeon , Song Minchul , Lim Joung Youl , Kang Yea Eun , Yi Hyon-Seung , Shong Minho
Published: June 2024

Thyroid cancer is a common endocrine malignancy with increasing incidence globally. Although most cases can be treated effectively, some cases are more aggressive and have a higher risk of mortality. Inhibiting RET and BRAF kinases has emerged as a potential therapeutic strategy for the treatment of thyroid cancer, particularly in cases of advanced or aggressive disease. However, the development of resistance mechanisms may limit the efficacy of these kinase inhibitors. Therefore, developing precise strategies to target thyroid cancer cell metabolism and overcome resistance is a critical area of research for advancing thyroid cancer treatment. In the field of cancer therapeutics, researchers have explored combinatorial strategies involving dual metabolic inhibition and metabolic inhibitors in combination with targeted therapy, chemotherapy, and immunotherapy to overcome the challenge of metabolic plasticity. This review highlights the need for new therapeutic approaches for thyroid cancer and discusses promising metabolic inhibitors targeting thyroid cancer. It also discusses the challenges posed by metabolic plasticity in the development of effective strategies for targeting cancer cell metabolism and explores the potential advantages of combined metabolic targeting.
Parathyroid Gland Generation from Pluripotent Stem Cells
Authors: Kano Mayuko
Published: June 2024

Patients with permanent hypoparathyroidism require lifelong treatment. Current replacement therapies sometimes have adverse effects (e.g., hypercalciuria and chronic kidney disease). Generating parathyroid glands (PTGs) from the patient’s own induced pluripotent stem cells (PSCs), with transplantation of these PTGs, would be an effective treatment option. Multiple methods for generating PTGs from PSCs have been reported. One major trend is in vitro differentiation of PSCs into PTGs. Another is in vivo generation of PSC-derived PTGs by injecting PSCs into PTG-deficient embryos. This review discusses current achievements and challenges in present and future PTG regenerative medicine.
Strategi Komunikasi Pemasaran PT. Mira Mirza Thoha Divisi Traktor Kota Samarinda Dalam
Authors: Adji Pratama Yuan , Molekandella Boer Kheyene , Hairunnis Hairunnis , Arum Sary Kezia
Published: June 2024

Ketatnya persaingan antar perusahaan membuat perusahaan melakukan upaya dalam menyusun strategi pemasaran untuk memasarkan produk atau jasa yang mereka tawarkan. Mereka bersaing agar mendapatkan daya tarik pelanggan supaya berminat untuk membeli atau memakai jasa produk yang ditawarkan perusahaan. Tujuan penelitian ini adalah untuk mendeskripsikan dan menganalisis stretegi komunikasi pemasaran yang terjadi pada MIM Traktor dalam membentuk loyalitas pelanggan. Metode penelitian yang dilakukan dengan deskriptif kualitatif. Fokus penelitiaan terdiri dari: Product, Price, Place, Promotion serta menambahkan Integrated Marketing Communication (IMC) untuk mengupas sisi komunikasi pemasaran nya. Teknik pengumpulan data dilakukan dengan cara observasi, wawancara dan dokumentasi. Hasil penelitian menunjukkan strategi komunikasi pemasaran pada PT.MMT MIM Traktor Samarinda dalam mempertahankan loyalitas pelanggan dari indikator product sudah baik sebab, MIM Traktor rutin mengganti alat berat setiap tahunnya agar pelanggan merasa senang atas kualitas yang diberikan. MIM Traktor diharapkan dapat mempertahankan kualitas produk alat berat yang disewakan, mengingat kualitas produk yang disewakan saat ini cukup baik. MIM Traktor diharapkan memanfaatkan media sosial sebagai sarana pengiklanan guna memperluas pemasaran serta penentuan harga sewa alat berat harus dipertimbangkan
The Influence of Eco Friendly Market Strategy and Brand Perception on Consumer Purchase Choices for Le Minerale Bottled Water at Surabaya
Authors: Syahrul Ilmi Galih , Kusuma W Nuruni Ika
Published: June 2024

This study aims to analyze the influence of Green Marketing and Brand Image on the purchasing decisions of Le Minerale bottled drinking water. The study uses a sample of 100 respondents, selected based on Ghozali's (2011) theory. The data analysis method used is regression analysis with an R2 value of 0.975130, indicating that the research model can explain 97.51% of the variability in purchasing decisions. The results show that Green Marketing has a significant effect on the purchasing decisions of Le Minerale, indicating that an effective Green Marketing strategy aligns with increased consumer purchasing decisions. Additionally, Brand Image is also found to have a significant influence on purchasing decisions, meaning that an improvement in Le Minerale's Brand Image corresponds to an increase in consumer purchasing decisions. These findings emphasize the importance of green marketing strategies and brand image in influencing consumer purchasing behavior.
Creating Renewable Energy from Agricultural Wastes in Nigeria and Enabling Policy and Legal Framework
Authors: H. I. Ogan, , F. O. Akaakar, , B. Agbogunleri,
Published: June 2024

Agricultural wastes will continue to rise as the demand for agricultural produce continues to increase to feed the growing world population. The processing of the agricultural produce and the management system of the wastes require energy, making it imperative to look for the energy source that will reduce the dire environmental consequences of fossil fuel. This study therefore aimed to estimate the renewable energy (electricity) that will be available from agricultural wastes in Nigeria, while the objectives are to review literate to identify the types and quantities of agricultural wastes, estimate the biogas potentials of the identified agricultural wastes, to determine the energy equivalent in firewood, for kerosine, and electricity generation from the biogas, as well as review the enabling policy and legal framework that empowers corporate bodies and individuals to generate electricity from biomass. This study relied on current available secondary data. Results from this study revealed that crop residue from maize, cassava, rice, sorghum represent 16.4%, 22.3%, 12.1% and 19.3% respectively; millet contributed (7.2%); cowpea (4.9%); others ranged from 0.1% (wheat) to 3.0% (yam). The estimated biogas potential in billion m3 year-1 revealed that cattle manure represents 47.9%, followed by crop residue (15.5%). Abattoir wastes represent 11.1% while goat manure represents 10.5%. Others are sheep (6.48%), poultry (6.28%) and pig (2.3%). This study further reported 578.4 million tons year-1 from cattle manure, 44.5 million tons year-1 from sheep manure, 72.1 million tons year-1 from goat manure. In terms of crop residues, this study reported a waste of about 6.2 billion tons year-1 in total. The value of biogas potential from this study revealed about 19.1 billion m3 from cattle manure, about 2.6 billion m3 from sheep and about 4.2 billion m3 from goat. In terms of potential electricity generation from these wastes, this study found about 18.7 billion kwh of electricity will be available for utilization. This study therefore recommends that Nigeria should consider the use of biomass as one of the ways to address her energy challenges, preserve her environment and become a self- reliant economy.
Financial Management Strategies for Implementing Lean Manufacturing in the Footwear Industry
Authors: Chandra Shekar Poturi , Perla Suryateja
Published: June 2024

The concept of lean manufacturing, initially developed to maximize resource utilization by minimizing waste, has evolved to address the needs of a rapidly changing and competitive business environment. Footwear industries face significant challenges and complexities that require a systematic and continuous response to maintain and enhance product value. Implementing lean manufacturing practices has become essential for these organizations to sustain and thrive in such a dynamic landscape. However, successful implementation is not solely dependent on operational adjustments but also on strategic financial management. This research examines the financial management strategies necessary for the effective implementation of lean manufacturing in the footwear industry. It emphasizes the importance of integrating financial planning with lean principles to ensure comprehensive and sustainable improvements. Key lean elements such as Value Stream Mapping (VSM), Cellular Manufacturing (CM), U-line systems, Line Balancing, Inventory Control, Single Minute Exchange of Dies (SMED), Pull Systems, Kanban, and Production Levelling are explored in detail. The study demonstrates how a focused approach to financial management can support these lean elements, enabling footwear companies to optimize resource allocation, reduce costs, and improve efficiency. By aligning financial strategies with lean manufacturing goals, organizations can achieve significant economic and operational benefits. This includes better cash flow management, investment in continuous improvement initiatives, and a robust framework for measuring the financial impact of lean practices. Through a comprehensive analysis of these financial strategies, the research provides valuable insights for footwear companies aiming to implement lean manufacturing successfully. It highlights the need for an integrated approach that combines financial acumen with lean methodologies to drive value creation, enhance competitiveness, and ensure long-term sustainability in the industry.
A Comprehensive Perspective of Huntington’s Disease
Authors: Shaheen Mohammad , Hari Chandana Tejomurtula , Hema Guddanti , Paturi Gayathri
Published: June 2024

Huntington's disease (HD) is a severe genetic illness caused by a CAG expansion on chromosome 4 in the huntingtin gene. This results in an excessively long polyglutamine tract, which has negative consequences. The normal huntingtin protein serves important tasks, however the mutant version causes a variety of detrimental effects. Disruptions in cellular processes such as autophagy, decreased mitochondrial activity, lysosomal dysfunction, and others are involved in the etiology of HD. Inflammation, oxidative stress, and transcriptional alterations all contribute to neurodegeneration. Despite great progress in understanding the genetic basis of HD, there is currently no cure. The current approach to management focuses on symptomatic control, but as our understanding of genetics advances, targeted medicines might become available. Although HD is still a difficult condition to treat, there is optimism for future advancements in research. Clinical techniques mostly focus on symptom management, with genetic testing assisting in diagnosis. Promising research looks on potential disease-modifying therapies, such as ways to reduce mutant huntingtin levels and improve clearance. Ongoing clinical research provide promise for future treatments, bringing hope to HD patients and their families.
Automated Hydroponic Farm System
Authors: Arun Naik Trupti , Sateesh Bhandiwad Smruti , Patil Shreya , Tashildar Rasika , H K Harish
Published: June 2024

Current agriculture faces a multitude of issues – limited seasons, excessive pesticide use, sustainability concerns in organic farming, high carbon footprint, and inconsistent produce quality. Traditional methods, restricted by seasons and harming the environment with pesticides, are struggling to keep up with a changing world. This paper proposes a groundbreaking solution: an automated hydroponic farm system. Unlike traditional methods, this system allows year-round, pesticide-free production through advanced growing stations using a precise nutrient delivery technique (NFT). To create perfect growing conditions, a Greenhouse Climate Control System with various sensors regulates factors like temperature, humidity, and light. Additionally, a Central Console acts as the brain of the system, connecting everything and monitoring the entire farm. By automating these processes, this hydroponic system aims to revolutionize agriculture, offering a sustainable, efficient, and high-quality alternative.
Masers and Star Formation Activities in W51A
Authors: Zhang Yan-Kun , Chen Xi , Wang You-Xin , Song Shi-Min , Liu Jun-Ting , Lu Ying
Published: June 2024

Concurrently with the maser flare observed in W51-North during the 3 month monitoring of H2O, NH3, and CH3OH maser variability from 2020 January to April using the Tianma 65 m Radio Telescope, we conducted Very Large Array mappings for these three maser species across the entirety of W51A region. After finding the ring-shaped H2O maser which might trace the disk surrounding the protostar residing in W51-North, the NH3 (9,6) maser delineated a jet which might be illuminated in the luminosity outburst possibly caused by the infalling streamer’s interaction with the protostar’s disk. An analysis of the comprehensive distribution of maser spots allowed us to affirm that W51N4 or ALMAmm31 serves as the primary source of the Lacy jet. Furthermore, we observed that class I methanol maser spots may extend beyond the locations of the H2O and NH3 (9,6) masers within the outflow. Additionally, emissions from other NH3 maser transitions coincided with specific 1.3 mm continuum sources. The arrangement of H2O maser spots in the vicinity of W51e2-E potentially indicates episodic accretions in this source. Combining the data from the Atacama Large Millimeter/submillimeter Array data archive for W51-North, W51e2, and W51e8, we have discovered that the H2O, NH3, and CH3OH masers, as well as the HC3N and SiO emissions are found to be good tools for tracing outflow in this work for W51A.
A Close Binary Lens Revealed by the Microlensing Event Gaia20bof
Authors: Bachelet E. , Rota P. , Bozza V. , Zieliński P. , Tsapras Y. , Hundertmark M. , Wambsganss J. , Wyrzykowski Ł. , Mikołajczyk P. J. , Street R. A. , Jaimes R. Figuera , Cassan A. , Dominik M. , Buckley D. A. H. , Awiphan S. , Nakhaharutai N. , Zola S. , Rybicki K. A. , Gromadzki M. , Howil K. , Ihanec N. , Jabłońska M. , Kruszyńska K. , Kruszyńska K. , Pylypenko U. , Ratajczak M. , Sitek M. , Rabus M.
Published: June 2024

During the last 25 yr, hundreds of binary stars and planets have been discovered toward the Galactic bulge by microlensing surveys. Thanks to a new generation of large-sky surveys, it is now possible to regularly detect microlensing events across the entire sky. The OMEGA Key Projet at the Las Cumbres Observatory carries out automated follow-up observations of microlensing events alerted by these surveys with the aim of identifying and characterizing exoplanets as well as stellar remnants. In this study, we present the analysis of the binary lens event Gaia20bof. By automatically requesting additional observations, the OMEGA Key Project obtained dense time coverage of an anomaly near the peak of the event, allowing characterization of the lensing system. The observed anomaly in the lightcurve is due to a binary lens. However, several models can explain the observations. Spectroscopic observations indicate that the source is located at ≤2.0 kpc, in agreement with the parallax measurements from Gaia. While the models are currently degenerate, future observations, especially the Gaia astrometric time series as well as high-resolution imaging, will provide extra constraints to distinguish between them.
Historical Fermi All-sky Variability Analysis of Galactic Flares
Authors: Joffre S. , Torres-Albà N. , Ajello M. , Kocevski D. , Buehler R.
Published: June 2024

The Fermi All-sky Variability Analysis (FAVA) provides a photometric alternative for identifying week-long gamma-ray flares across the entire sky while being independent of any diffuse Galactic or isotropic emission model. We reviewed 779 weeks of Fermi Large Area Telescope data analyzed by FAVA to estimate the rate and origin of Galactic gamma-ray flares, and to search for new variable Galactic gamma-ray transients. We report an estimated yearly rate of ∼8.5 Galactic gamma-ray flares yr–1, with ∼1 flare yr–1 coming from unknown sources. Out of the known gamma-ray sources that are spatially coincident with these detected flares, we report gamma-ray flares for six of them for the first time. All six are classified as pulsars, or a source of unknown nature but which positionally overlaps with known supernova remnants or pulsar wind nebulae (PWNe). This potentially means these sites are tentative candidates to be the second known site of a variable gamma-ray PWN, after the famous Crab Nebula’s PWN. Additionally, we identify nine unassociated flares that are unlikely to have originated from known gamma-ray sources.
Spontaneous Caecal Perforation in a Male Neonate: A Case Report
Authors: Banu Syahar
Published: June 2024

BACKGROUND: Spontaneous perforation of the colon in full-term neonates is a rare case, with perforation of the cecum being rarely reported.
CASE PRESENTATION: We present a rare case of spontaneous perforation of the cecum in a term neonate who presented with vomiting and flatulence on the second day of life. Surgical intervention revealed full-thickness perforation in the caecum. Histopathologically, there was no necrotizing enterocolitis and Hirschsprung’s disease.
CONCLUSION: Clinica diagnosis and hopefully prompt surgical management.
A study of tumor budding and the factors, affecting interpretability of peritumoral budding, based on endoscopic colorectal biopsies from the left and right sided colorectal carcinoma
Authors: Petrov Krasimir T. , Ivanov Ivan , Betova Tatyana , Tsvetkova Reni , Trifonov Radoslav , Popovska Savelina
Published: June 2024

In this paper we summarize the results of a retrospective investigation of tumor budding in endoscopic preoperative biopsies in patients with colorectal adenocarcinoma (CRC). The aim of this study was to assess the peritumoral budding evaluation interpretability, based on endoscopic colorectal biopsies in left and right sided colorectal carcinoma and some of the factors that influence it. A group of 100 patients, with preoperative endoscopic biopsies was selected and the tumor buds were counted on H&E stained slides, according to contemporary clinical recommendations. In the studied patient group, budding was identified in a total of 13 patients (13% of the studied cases). The primary localization of the tumor in the left or right colon was not associated with the reporting of budding in endoscopic biopsies of colorectal carcinoma. No budding was observed in highly differentiated tumors, and the presence of budding was reported less frequently in poorly differentiated tumors compared to moderately differentiated ones. Budding was accessible for evaluation in nearly 1/10 of the small biopsies from CRC. Artifacts from the sample management as well as factors related to the tumor characteristics predetermined the possibility for evaluation of tumor budding on small biopsies.
Clivage au moi chez Eneko
Authors: Gaudriault Pierre
Published: June 2024

Cette étude illustre la façon dont René Roussillon reprend la notion freudienne de clivage du moi pour l’appliquer à une déchirure du moi dont une partie est désubjectivée, ce qu’il nomme « clivage au moi » (1999). Cela survient chez Eneko sous la forme d’une crise délirante, laissant après coup son psychisme dans un état de désolation dont il lui sera difficile de sortir. Les traces de cette crise vont se manifester pendant longtemps sous la forme d’un clivage, que l’on pourrait appeler « résiduel », qui va continuer à aliéner le moi et handicaper son adaptation socio-affective. Le travail psychique accompli dans des entretiens psychothérapeutiques et dans un hôpital de jour va lui permettre de retrouver une certaine intégrité psychique.
L’adolescent chrysalide engagé dans l’espace virtuel
Authors: Bailly Rémi , Vlachopoulou Xanthie
Published: June 2024

Le retrait social et scolaire à l’adolescence est une manifestation psychopathologique ancienne, mais qui de nos jours va souvent de pair avec un usage excessif des écrans. Les auteurs y voient un lien : aux transformations du corps et du psychisme à l’adolescence, s’ajoute désormais celle du bouleversement de leur existence numérique. Dans cette forme d’ascétisme moderne, le jeune en retrait social et scolaire semble déposer sa pulsionnalité dans les mondes virtuels et rester immobile, hors espace, dans une temporalité suspendue. Pour venir en aide à ces adolescents, les auteurs proposent un « dispositif mobile et numérique » avec le projet de construction d’une plateforme virtuelle, à mi-distance, afin d’y inclure toutes les facettes de leur être et d’y introduire du mouvement.
Passer par l’hôpital après le passage à l’acte
Authors: de Kernier Nathalie
Published: June 2024

Est proposée une réflexion sur les fonctions de l’hospitalisation après un geste suicidaire et, en particulier, le travail psychologique, à l’appui de l’exemple d’une adolescente de 11 ans tourmentée par les changements qu’elle commence à ressentir, et dont l’acte suicidaire est déclenché par la résurgence du souvenir de décès dans l’après-coup, la mort s’imposant soudainement de manière traumatique. Le dispositif s’étend à un suivi post-hospitalier et la comparaison de deux bilans projectifs afin d’observer l’évolution du fonctionnement psychique, et de favoriser une prévention et l’adhésion aux soins. Ainsi, chez l’adolescente dont il est ici question, l’expression de la conflictualité apparaît plus aisée un an plus tard, amorçant une possibilité de se séparer et de se subjectiver.
Réflexions cliniques et éthiques, analyse du discours et de la demande transidentitaire
Authors: Lions Axel
Published: June 2024

L’auteur tente de saisir les enjeux du discours LGBTQIA+ au sein de la problématique transidentitaire chez les adolescents. Face à la conviction de certains adolescents de ne pas être dans le bon corps, et la demande de transition qui en découle, les institutions doivent s’adapter tant sur le plan de l’éthique que sur l’innovation des dispositifs d’accompagnements. À travers la demande de transition de P., adolescente de 15 ans, l’auteur questionne en quoi cette demande peut amener le soignant à une place de supposé pouvoir, éloignée de son positionnement originaire. Ce décalage empêcherait la rencontre intime de l’adolescent avec sa dysphorie et lui limiterait l’accès à une part insue de lui-même. Cette bascule dans le positionnement est signifiée aussi dans le discours de la société et dans les institutions par la création de parcours de soins où s’organise la position de spécialiste et de programmateur en santé mentale, en dépit d’une prudence et d’une approche clinique psychanalytique de la transidentité.
Autour de l'œuvre de Jean-Paul Valabrega
Authors: Isnard-Davezac Nathalène
Published: June 2024

C’est à l’esprit de résistance qui a marqué l’homme, son œuvre et sa vie que nous voulons, ici, rendre hommage. Au bâtisseur aussi qui apporta non seulement une pensée novatrice à la métapsychologie freudienne, mais qui contribua, en outre, par sa critique créatrice à fonder une théorie de la formation des psychanalystes singulière qui a inspiré celle que revendique et défend le Quatrième Groupe.
Autour de l'œuvre de Jean-Paul Valabrega
Authors: de Mijolla-Mellor Sophie
Published: June 2024

Depuis « Phantasme, mythe, corps et sens » à « Les mythes, conteurs de l’inconscient », la question du mythe n’a cessé d’interroger Jean-Paul Valabrega. Le mythe, ainsi qu’il le rappelle, ignore la chronologie. L’auteur souligne par ailleurs que dans le phantasme, le mythe, le rêve et le délire, il y a simultanément permanence d’un thème central et métamorphose des représentations traductrices de ce thème. Or précisément cette simultanéité contradictoire n’est pas rendue dans les théories sexuelles infantiles « typiques » dont nous parle Freud. C’est la raison pour laquelle, ainsi que je le développerai, il me paraît nécessaire de se référer, en amont des théories sexuelles infantiles, à un stade antérieur que j’ai appelé les « mythes magico-sexuels ». On peut donc prolonger la dyade Mythe/Phantasme, en une triade : Mythe/Phantasme/Théorie primitive.
Combates políticos y culturales por la significación de la religiosidad popular durante la II República
Authors: Rina Simón César
Published: June 2024

La religiosità popolare è stata, in età contemporanea, uno spazio di conflitto e un potente strumento per la costruzione di uno spazio di legittimazione, così come di immaginari culturali. Questo lavoro è un approccio teorico al concetto di “popolare” e ai molteplici significati dei suoi riti, applicato a un periodo di particolare effervescenza politica: l’esperienza democratica della Seconda Repubblica. In questo contesto, la Settimana Santa, a causa del suo potenziale in termini di visibilità delle élites e nella costruzione delle identità, rappresentò un terreno di scontro tra diversi modi di intendere la cultura popolare, la tradizione e il sacro. Ci siamo concentrati sul caso significativo del boicottaggio anti-repubblicano a Siviglia, che venne stato emulato in altre città andaluse ed esemplifica gli usi politici di questi fenomeni al contempo festivi e identitari.
Religiosidad, secularización y cultura antirrepublicana en el entorno educativo: Valladolid 1931-1936
Authors: Rodríguez Serrador Sofía
Published: June 2024

La proclamazione della Seconda Repubblica spagnola, accolta con entusiasmo in molti settori, avviò un periodo di progresso e mutamento sociale. Ciononostante il cattolicesimo conservatore diffidava dello spirito secolarizzatore della legislazione repubblicana e delle misure che toccavano direttamente il settore dell’istruzione – come lo scioglimento della Compagnia di Gesù o dalla Ley de Confesiones y Congregaciones Religiosas -, sino ad allora tradizionale dominio degli ordini religiosi. In questo articolo analizzeremo come il nuovo dettato costituzionale, assieme alla nascente cultura repubblicana, poté influire all’interno dei collegi privati cattolici di Valladolid nel condizionare le pratiche religiose, incidendo direttamente nella creazione di sentimenti di opposizione al governo repubblicano che si manifestarono in differenti maniere.
La dialéctica religiosa del fascismo español. Liturgia política y prensa jonsista: los casos de «Libertad» e «Igualdad»
Authors: Tomasoni Matteo
Published: June 2024

Nel quadro dei fascismi europei del XX secolo il caso spagnolo tende a differenziarsi per la costante ricerca dell’unità ideologica e dell’affermazione sociale. Dai suoi inizi e attraverso il movimento jonsista fondato nel 1931, si osservano non poche difficoltà per unificare metodo e propaganda senza dimenticare la mancanza di coesione e i frequenti dibattiti interni. Il jonsismo impresse profondamente il consolidamento di uno spazio fascistizzato in Spagna, essendo la religione cattolica uno strumento centrale del suo discorso politico. Secondo i dirigenti del partito l’appropriazione del discorso religioso – inteso tramite la sua retorica trasformata in liturgia politica – fu una delle chiavi per la creazione di un progetto politico efficace per contrastare l’anticlericalismo del regime repubblicano. Tradizione, spiritualità, e nazione diventarono l’asse della propaganda fascista, i cui principali organi di stampa «Libertad» y «Igualdad» non tardarono a difendere durante la sua breve ma intensa traiettoria politica.
RONCHI-FIUME 1919-2019
Authors: Manenti Luca°G.
Published: June 2024

La mostra racconta la spedizione fiumana, partita da Ronchi nel 1919, attraverso le carte d’epoca conservate presso il Consorzio Culturale del Monfalconese, il Comune di Ronchi dei Legionari, l’Istituto regionale per la storia della Resistenza e dell’Età contemporanea nel Friuli Venezia Giulia. Viene inoltre per la prima volta esposta al pubblico la collezione della famiglia Adami, erede di Attilio, uno dei sette giurati di Ronchi, comprensiva di lettere e cimeli.
Les didactiques des disciplines scientifiques : se rencontrer, dialoguer et cheminer ensemble
Authors: Abboud Maha , Hosson Cécile de
Published: June 2024

In this introductory paper to the special issue of the « Annals of Didactics and Cognitive Sciences, » we provide an account of the lectures delivered during the « Rendez-vous en Didactique » conference held in Paris from May 30 to June 3, 2022. The beginning of the paper revisits the conference’s rationale and the request made to the invited speakers, framed within the perspective of dialogue among didactics from various scientific disciplines. Subsequently, we present some reference points to delimit and differentiate the so-called inter, trans, and multidisciplinarity approaches. This clarification allows us to position the approaches of the lecturers in response to the conference organizers’ request. A brief presentation of their contributions reflects the diversity of the adopted approaches. We conclude this paper by raising questions about these approaches and discussing the significance of this « unique » scholarly output, in which researchers from multiple fields have made an effort to understand each other, engage in dialogue, and endeavor to propose common perspectives for their respective communities.
Pratiques in situ d’enseignants-chercheurs et confrontation avec le vécu des étudiants : une étude de cas en mathématiques et en physique
Authors: Bridoux Stéphanie , Grenier-Boley Nicolas , Lebrun Nathalie
Published: June 2024

This research focuses on the teaching practices of teacher-researchers (TRs) in a lecture context. Their declared practices were studied using the sociological notion of professional identity. The analysis of the verbatim, collected during interviews with 5 TRs indicates a strong attachment to the epistemology of their discipline and a willingness to interact with the student audience to facilitate learning. However, the analysis of students' answers to a questionnaire proposed at the end of the lecture shows a misunderstanding between their intentions and the students' experience. We have identified two profiles of TRs: some encourage interaction during the course by overlooking some of the students' difficulties, while others give too many details or use a medium that hinders learning.
De Francfort à Montpellier et de Montpellier à la Vis de Saint-Gilles
Authors: Durand Bernard
Published: June 2024

Partager ! Le verbe résume des années de croisements allant d’étapes de silences à d’intenses collaborations, portées par une relation amicale aidant à affronter thèmes communs ou pistes nouvelles : sur l’office du juge, le ministère public, l’Europe des dictatures, le droit sous Vichy, etc. Mais c’est sur l’histoire du droit administratif et le droit de « Haute » police que le professeur Stolleis fut un modèle en nous « poussant » à entrer plus avant dans le « droit administratif » de l’Ancien Régime, sa projection sur les territoires coloniaux, et sa construction par des juges « made-law ».
Unconventional IFNω-like Genes Dominate the Type I IFN Locus and the Constitutive Antiviral Responses in Bats
Authors: Geng Rong , Wang Qi , Yao Yu-Lin , Shen Xu-Rui , Jia Jing-Kun , Wang Xi , Zhu Yan , Li Qian , Shi Zheng-Li , Zhou Peng
Published: June 2024

Bats are the natural reservoir hosts of some viruses, some of which may spill over to humans and cause global-scale pandemics. Different from humans, bats may coexist with high pathogenic viruses without showing symptoms of diseases. As one of the most important first defenses, bat type I IFNs (IFN-Is) were thought to play a role during this virus coexistence and thus were studied in recent years. However, there are arguments about whether bats have a contracted genome locus or constitutively expressed IFNs, mainly due to species-specific findings. We hypothesized that because of the lack of pan-bat analysis, the common characteristics of bat IFN-Is have not been revealed yet. In this study, we characterized the IFN-I locus for nine Yangochiroptera bats and three Yinpterochiroptera bats on the basis of their high-quality bat genomes. We also compared the basal expression in six bats and compared the antiviral and antiproliferative activity and the thermostability of representative Rhinolophus bat IFNs. We found a dominance of unconventional IFNω-like responses in the IFN-I system, which is unique to bats. In contrast to IFNα-dominated IFN-I loci in the majority of other mammals, bats generally have shorter IFN-I loci with more unconventional IFNω-like genes (IFNω or related IFNαω), but with fewer or even no IFNα genes. In addition, bats generally have constitutively expressed IFNs, the highest expressed of which is more likely an IFNω-like gene. Likewise, the highly expressed IFNω-like protein also demonstrated the best antiviral activity, antiproliferative activity, or thermostability, as shown in a representative Rhinolophus bat species. Overall, we revealed pan-bat unique, to our knowledge, characteristics in the IFN-I system, which provide insights into our understanding of the innate immunity that contributes to a special coexistence between bats and viruses.
Comparison of Double Endobutton and Clavicular Hook Plate in Acromioclavicular Joint Disruption: A Systematic Review and Meta-analysis
Authors: Gupta Govind Kumar , Halder Subhajit , Rani Sudha , Chakraborty Ratnajeet , Kumar Amit , Kumar Tushar
Published: June 2024

Background:

Acromioclavicular joint (ACJ) disruptions are corrected by surgery either with an endobutton or a hook plate. The results in the long term were found to be similar in many randomized controlled trials. This study aims to conduct a meta-analysis to evaluate the functional outcome and complications of double endo button versus clavicular hook plate (CHP) for ACJ disruption (Rockwood types III–VI).

Materials and Methods:

Two authors independently searched related articles from electronic databases (PubMed, Google Scholar, MEDLINE, SCOPUS, and Web of Science) till January 26, 2022. The data were extracted from the related articles and analyzed by Stata software. For bias calculation of each study, the Newcastle–Ottawa scale and the RevMan 5.4 software were used.

Results:

14 cohort studies, 2 randomized control trial studies, and 1 case–control study including patients were selected in this meta-analysis. The results of our study showed a significantly higher Constant–Murley Score (WMD 5.79, 95% confidence interval [CI] 2.23–9.36), Visual Analog Scale (WMD− 0.63, 95% CI [−0.79, −0.46]) and University of California at Los Angeles shoulder score (UCLA) scale (WMD 3.32, 95% CI [2.87, 3.77]) for double endobutton group. At the same time, some complications like implant failure were more common in the double endobutton group.

Conclusion:

This meta-analysis shows better functional and clinical outcomes of shoulder joint for the treatment of acromioclavicular joint (ACJ) disruption cases (Rockwood types III–VI) with no need for secondary operation, unlike the CHP. Complications like subacromial erosion, ACJ arthrodesis, and infection rate are higher in the CHP group, whereas the chance of implant failure is higher in the double endobutton group.
Nonmotor Symptoms and Impulse Control Disorders in Parkinson’s Disease Patients in India: A Cross-sectional Study
Authors: Varshney Amit , Kumar Pankaj , Ram Vidya Sagar
Published: June 2024

Introduction:

Parkinson’s disease (PD) is a prevalent neurodegenerative disorder with significant nonmotor symptom (NMS) burden, including impulse control disorders. This study aimed to comprehensively evaluate NMS and impulse control disorders in PD patients under primary care.

Materials and Methods:

A descriptive cross-sectional study was conducted on 32 PD patients and evaluated using standardized assessment tools. Demographics, comorbidities, and symptom burdens were recorded. Evaluation tools included the Hoehn and Yahr Scale, REM Sleep Behavior Disorder assessment, Geriatric Depression Scale, Montreal Cognitive Assessment scale for cognitive impairment, NMS scale, and identification of impulse control disorders.

Results:

In PD, comorbidities were prevalent (84%), and most were at Hoehn and Yahr Stages 2 and 3. REM Sleep Behavior Disorder was present in 28.12%, with 5 receiving clonazepam treatment. Depression affected 28.12%, with 5 receiving pharmacological treatment. Cognitive impairment was notable in 9 patients. NMS burden was high, with varying severity. Impulse control disorders were limited, whereas one case of dopamine dysregulation syndrome was identified.

Discussion:

This primary care-based study in India assessed NMS and impulse control disorders in PD patients, highlighting comorbidities and management opportunities. The study’s strength lies in evaluating an unselected primary care population, whereas limitations include small sample size.

Conclusion:

This study emphasizes the importance of primary care physicians in monitoring and managing NMS in PD patients. Impulse control disorders and cognitive impairment are critical aspects that need attention. The findings support an integrated approach involving health-care professionals across various disciplines to provide holistic care for PD patients.
The Pinhole Surgical Technique - A Distinct Approach for a Marginal Tissue Recession Coverage Using Amniotic Membrane
Authors: Patel Chandni , Solanki Vanraj , Dattani Vidhi , Gajjar Shreya , Girdhar Gaurav , Joshi Surabhi , Kumar Santosh
Published: June 2024

Introduction:

Root coverage procedures are often carried out for compromised aesthetics, dentinal hypersensitivity, difficulty in the maintenance of plaque control, root caries and bone loss. Regenerative attempts are hindered by the root surface’s avascularity and microbiologically compromised condition. Furthermore, freshly created tissue needs to withstand the physical pressures of mastication and procedures related to the maintenance of oral hygiene by the patient. The key issues include surgical challenges, time and patients’ discomfort despite the various surgical methods that have been performed for the root coverage. The complications related to donor site, sparked interest for the development of newer innovative techniques that helps to meet patient’s aesthetic and functional needs. Pinhole surgical technique (PST) being minimally invasive is used in our study to treat gingival recession using amniotic membrane.

Materials and Methods:

A total of 20 participants were selected randomly with having Miller’s Class I or II recession. Each patient received thorough information on how to practice good oral hygiene. A scaling and root planning process was carried out across the entire mouth. Re-evaluation of research sites was done 1 month after phase I therapy to validate its appropriateness. PST was done randomly on the chosen sites, along with the application of amniotic membrane.

Results:

All the clinical parameters i.e., recession depth (RD), recession width (RW) and clinical attachment level (CAL), were seen improving significantly at 6 months postoperatively compared to baseline except width of keratinized gingiva (WKG) (P = 0.08) and thickness of keratinized gingiva (TKG) (P = 0.14). All the clinical parameters i.e., RD (P = 0.017), RW (P = 0.017), probing depth (P = 0.03) and CAL (P = 0.05) improved significantly at 12 months postoperatively compared to baseline. However, WKG and TKG showed statistically insignificant changes at 12 months postoperatively (P = 0.08, P = 0.14). Significant difference in Visual Analogue Scale score was seen postoperatively at day 1, 3 and 5.

Conclusion:

Pinhole surgical approach is used to treat Miller’s Class I–II recession. It may be a better option than the other techniques because it is less invasive, time and money efficient. For the establishment of a normal vasculature and early wound healing, the usage of amniotic membrane as an adjunct is a better alternative.
Emergence of Multidrug-resistant Acinetobacter baumannii: A Growing Health Concern in the Qassim Region, Kingdom of Saudi Arabia
Authors: Banawas Saeed S.
Published: June 2024

Introduction:

Acinetobacter baumannii is a multidrug-resistant bacterium commonly associated with hospital-acquired infections. The rapid spread of A. baumannii has raised concerns, as it has been linked to the emergence of clones in healthcare facilities worldwide. The challenges of treating and controlling infections caused by this bacterium in hospital settings are exacerbated by its resistance profile. The proliferation of clones worldwide highlights the need for careful infection control procedures and new tactics to fight illnesses caused by drug-resistant A. baumannii strains.

Materials and Methods:

Between January 2019 and December 2020, a total of 26,250 specimens were collected by personnel from the Department of Microbiology at King Fahad Specialist Hospital.

Results:

Our study highlights a significant surge in antimicrobial resistance, indicating a relative increase in multidrug-resistant A. baumannii isolates. Despite extensive resistance, azithromycin, cefoxitin, norfloxacin, penicillin, piperacillin, tetracycline, ceftriaxone, nitrofurantoin and aztreonam showed 91.2%–100% efficacy against these strains.

Conclusions:

This study emphasises the critical need for stringent infection control measures and judicious antibiotic strategies to curb multidrug-resistant A. baumannii outbreaks in healthcare settings. The identification of alternative therapies is imperative for improved management of infections caused by multidrug-resistant A. baumannii.