bluuebunny/crossref_metadata_2025 huggingface dataset:
Wilson's Matrix Method for Calculating Molecular Vibration Frequencies and Normal Modes for Smart Materials
Authors: Jindal Ruby , Tripathi Archana , Saini Neenu
Published: August 2023

This book chapter provides an in-depth exploration of Wilson's matrix method, a computational technique used to calculate molecular vibration frequencies and normal modes in smart materials. The chapter begins with an introduction to molecular vibrations and normal modes, emphasizing their importance in understanding material behavior at the molecular level. It then delves into the theoretical foundation and practical steps involved in Wilson's matrix method, highlighting its use of force constants and eigenvalue calculations to determine vibrational frequencies and associated modes. The chapter further examines the application of Wilson's matrix method to smart materials, emphasizing their unique vibrational characteristics and the role of molecular vibrations in shaping their functionality. The advancements in the method, including the inclusion of anharmonicity and improved force constant determination, are discussed, along with the integration of enhanced computational techniques and increased computational power.
Book Review
Authors: Ren Yuan
Published: August 2023

This book explores how blockchain technology is disrupting economies and transforming societies. It offers detailed insights into the synergistic and complementary effects of blockchain and other new and emerging technologies such as artificial intelligence, the internet of things, satellite imagery, and digital twins. The book highlights how the developments of ecosystems around blockchain are helping to realize the potential of this technology to act as a “trust machine” across more contexts and settings. Multidisciplinary in both scope and perspectives, the book looks at blockchain's potential for impacting challenges in supply chain management, security, privacy and compliancy issues, and transforming payment and settlement systems. It further provides insights into the opportunities, barriers, and enablers of blockchain adoption by organizations.
Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway
Authors: Tang Zhongzhu , Wang Lei , Chen Yunwang , Zheng Xiaomin , Wang Runyu , Liu Bingxue , Zhang Shiqi , Wang Huimin
Published: August 2023

Quercetin (Que) has been proven to enhance the chemosensitivity of multiple cancers, including colon cancer (CC). However, whether the combination of Que and 5-fluorouracil (5-FU) has a synergistic effect on drug-resistant CC cells has not previously been reported. The effect of Que (5 and 10 μg/mL) on cell vitality and apoptosis of CC and CC drug-resistant cells was examined using a cell counting kit-8 (CCK-8) and flow cytometry. After cells were treated with 5-FU (10, 40 μg/mL), Que (10 μM, 40 μM), or 5-FU in combination with Que, cell proliferation, apoptosis, oxidative stress-related factors, reactive oxygen species (ROS), and nuclear factor erythroid 2-related factor (Nrf2)/heme oxygenase-1 (HO-1) pathway-related factors were examined by colony formation assay, flow cytometry, ELISA, ROS kit, immunofluorescence assay, and Western blot. The results showed that 5-FU reduced cell viability and induced apoptosis of CC as well as 5-FU-resistant CC cells. Que further restrained the proliferation, oxidative stress-related factors (SOD, CAT, GPx, and GR), ROS production, and induced apoptosis in CC cells and 5-FU-resistant CC cells induced by 5-FU. Moreover, the combination of Que and 5-FU attenuated the Nrf2/HO-1 pathway-related marker levels in CC cells and 5-FU-resistant CC cells. Therefore, our results suggest that Que reverses 5-FU resistance in CC cells via modulating the Nrf2/HO-1 pathway.
Impact of Neck Proprioception and Central Sensitization on Balance Outcomes in Patients with Chronic Neck Pain
Authors: Ramalingam A. Thangamani , Senthil Kumar S. N. , Rana Dinal , Gadhiya Akshita , Patel Shifa , Khan Nazaha
Published: August 2023

Context:

Currently, multiple researches demonstrate that proprioception of the neck has a favorable effect and a direct association with balance in individuals with chronic neck pain (CNP). However, there is a paucity of the literature that has attempted to quantify the impact of proprioception on balance in CNP patients and to determine the function of central nervous system sensitization (CS) in CNP patients.

Aims:

The goal of this study was to determine the variance component of proprioception on balance in CNP patients and to examine if there was a difference between centrally sensitized and nonsensitized CNP patients.

Settings and Design:

A cross-sectional, observational study was conducted in the outpatient department of a tertiary care hospital.

Materials and Methods:

Thirty-seven patients with CNP were assessed for proprioception, static and dynamic balance was using head repositioning accuracy (HRA) test, Brief Balance Evaluation Systems Test, step test, four-step square test, and Y-balance test. Disability and nervous system sensitization was assessed using the Neck Pain and Disability Scale and central sensitization inventory (CSI).

Statistical Analysis Used:

Kolmogrov–Smirnov test, Pearson correlation coefficient was used for statistical analysis.

Results:

The impact of CSI and HRA scores on static and dynamic balance scores was unpredictable, ranging from a minimum of 10% to a maximum of 38.7%.

Conclusion:

There is a weak evidence to suggest that proprioception component could have contributed to the variance in static, dynamic balance and disability in patients with centrally sensitized CNP.
Plasmodium vivax Malaria in Duffy-Positive Patients in Rwanda
Authors: van Loon Welmoed , Oliveira Rafael , Bergmann Clara , Habarugira Felix , Tacoli Costanza , Jäger Julia , Savelsberg Darius , Mbarushimana Djibril , Ndoli Jules M. , Sendegeya Augustin , Bayingana Claude , Mockenhaupt Frank P.
Published: August 2023

Plasmodium vivax is the second-most common malaria pathogen globally, but is considered very rare in the predominantly Duffy-negative sub-Saharan African population. In 259 malaria patients from highland southern Rwanda, we assessed Plasmodium species and Duffy blood group status by polymerase chain reaction (PCR). Plasmodium falciparum, P. vivax, Plasmodium malariae, and Plasmodium ovale were seen in 90.7%, 8.1%, 11.6%, and 5.0%, respectively. Plasmodium vivax occurred more frequently as a monoinfection than in combination with P. falciparum. All P. vivax–infected individuals showed heterozygous Duffy positivity, whereas this was the case for only 3.1% of patients with P. falciparum monoinfection and malaria-negative control subjects (P < 0.01). Based on PCR diagnosis, P. vivax is not rare in southern Rwanda. All episodes of P. vivax were observed in heterozygous Duffy-positive patients, whereas elsewhere in Africa, P. vivax is also reported in Duffy-negative individuals. Refined mapping of Plasmodium species is required to establish control and elimination strategies including all malaria species.
Molecular Epidemiology and Assemblage Typing of Giardia duodenalis in School-Age Children Situated along the Southern Shoreline of Lake Malawi, Malawi
Authors: Archer John , Cunningham Lucas J. , Juhàsz Alexandra , Jones Sam , Doull Ffion , LaCourse James E. , Mainga Bright , Makaula Peter , Kayuni Sekeleghe A. , Musaya Janelisa , Stothard J. Russell
Published: August 2023

Almost all human giardiasis infections are caused by Giardia duodenalis assemblages A and B. Differentiation between human infections with these assemblages, as well as between single-assemblage (A or B) and mixed-assemblage (A and B) infections, is therefore needed to better understand the pathological impact of infection with either, or both, assemblages. We assessed the prevalence of G. duodenalis assemblages A and B using 305 fecal samples provided by school-age children situated along the southern shoreline of Lake Malawi. Concurrently, intestinal pathology data were also collected to test for association(s) between assemblage infection status and intestinal health. Prevalence of G. duodenalis infection was 39.3% by real-time polymerase chain reaction. Of all identified infections, 32% were single G. duodenalis assemblage A and 32% were single G. duodenalis assemblage B, whereas 33% were mixed-assemblage infections. Fifteen unique G. duodenalis assemblage A and 13 unique G. duodenalis assemblage B β-giardin haplotypes were identified. There was a positive association between single infection with G. duodenalis assemblage B and both self-reporting of abdominal pain (odds ratio [OR]: 3.05, P = 0.004) and self-reporting of diarrhea (OR: 3.1, P = 0.003). No association between single infection with assemblage A and any form of intestinal pathology was found. Additionally, there was a positive association between mixed-assemblage infections and self-reporting of abdominal pain (OR: 3.1, P = 0.002). Our study highlights the importance G. duodenalis assemblage typing and reaffirms the need for improved access to water, sanitation and hygiene infrastructure in rural areas of low- and middle-income countries.
Analyzing the Usage of Wankel Engine Technology in Future Automotive
Powertrains
Authors: Mittal Vikram , Shah Rajesh , Przyborowski Alexandra
Published: August 2023

The Wankel engine is an eccentric rotary internal combustion engine known for its
simplicity, compactness, reliability, and efficiency. However, issues related to
sealing, efficiency, and emissions have hindered its widespread use. Recent
advancements in sealing technology, novel designs, material coatings, and
alternative fuels have addressed some of these problems, leading to improvements
in Wankel engine performance. This study examines these advancements in Wankel
engine technology and proposes three potential applications for future
automotive use. The first application involves utilizing a Wankel engine with a
continuously variable transmission to replace the powertrain in conventional
vehicles. The second application suggests replacing the engine in a
series-parallel electric-hybrid architecture with a Wankel engine. Lastly, the
third application explores using a Wankel engine as a range extender for
electric vehicles. To evaluate the benefits in terms of fuel consumption for
different drive cycles, each of these applications was modeled using the Future
Automotive System Technology Simulator (FASTSim). The models were assessed with
both standard Wankel engines and those incorporating recent advancements. The
results indicate a potential reduction in fuel consumption when utilizing
improved Wankel engine designs compared to traditional piston-based engines.
However, it should be noted that these improved Wankel engines still face
significant challenges regarding hydrocarbon emissions. Furthermore, the study
identified a promising application for Wankel engines as range extenders in
electric vehicles, suggesting their potential to enhance the overall efficiency
of electric transportation.
TOC
Authors: Tobolski Sue
Published: August 2023

TOC
Development and Realization of a 4x4 Vedic Multiplier Utilizing Cadence Platform
Authors: Prasad M.V. Tejendra
Published: August 2023

This study presents a pioneering approach to designing a Vedic multiplier using full adders and conducts a comprehensive power analysis to assess its energy efficiency. Vedic mathematics, rooted in ancient Indian principles, offers innovative techniques for rapid and precise computations. Leveraging these principles, we propose a Vedic multiplier architecture that exploits full adders as fundamental building blocks, enabling efficient multiplication operations through the Gate Diffusion Input (GDI) method. The thorough power analysis ensures a comprehensive evaluation of its energy-saving potential. This research aims to explore how Vedic mathematics can offer alternative and energy-efficient solutions for modern computational systems, particularly in performing multiplication operations. By embracing this novel methodology, we aspire to unlock new possibilities for efficient and sustainable computing paradigms.
Important Role of Entrepreneurship Readiness in Education
Authors: Istiqomah Irni , Suparji  , Marniati
Published: August 2023

Entrepreneurial skills, market orientation, and networking have a positive influence on entrepreneurial competence. Then entrepreneurial competence and entrepreneurial skills and networking have a positive influence on business performance. There is a significant influence of entrepreneurial competence in relation to entrepreneurial skills, marketing, networking and business workers. Entrepreneurship education in tourism is very important to improve the innovation skills of entrepreneurs in a dynamic environment. There is a positive impact of entrepreneurship education on business. Seeing the urgency of entrepreneurship education, therefore this article aims primarily to discuss the importance of entrepreneurship readiness in education. The reason why entrepreneurship education is included in the school curriculum and students should not be ruled by people or the government but they create jobs for themselves, this will also provide benefits for social and community welfare.
E-Book Development of Static Fluid Contents to Improve Students' Numeracy Literacy Competence
Authors: Kartiko Muhammad Ziyyauddin Purwo , Widodo Wahono , Madlazim Madlazim
Published: August 2023

This study aims to develop an E-Book on Static Fluid Content in Tutoring as an educational partner to improve students' numeracy literacy competence. E-Book development is carried out using the 4-D development model which consists of defining, designing, developing, and disseminating stages. The research instruments used were E-Book validation sheets and questions that were tested on material expert lecturers and media expert lecturers from Surabaya State University. The validation results show that the E-Book developed has a very valid quality, with a validity percentage of 97%. Aspects of presentation feasibility, content feasibility and linguistic feasibility in the E-Book as a whole meet the criteria of "Very Valid" (85-100%) based on the validity interpretation table. In addition, the validity of the pre-test and post-test questions in the E-Book also proved high with a validity percentage of 89%. The questions measure students' ability to identify facts, formulate mathematical problems, use mathematical concepts, facts, procedures, and reasoning in the context of static fluids, carry out calculations based on certain rules or formulas, and interpret numeracy to solve problems. With the results of a high percentage of validity, this Static Fluid E-Book is reliable and feasible to use as teaching material media in improving students' numeracy literacy competencies. Interactive features in the E-Book, such as "Go Watch", "Mind Map", "Go Information", "Go Concept", "Problem Drilling", and "Reflection", provide interesting and diverse learning experiences for students in understanding static fluid concepts.
Pengaruh Pertumbuhan Ekonomi dan Pertumbuhan Angkatan Kerja Terhadap Tingkat Pengangguran Di Kota Pekalongan
Authors: Kurniawan Pratomo Cahyo , Khilmiana Nala , Arifin Sandi , Maisaroh Asih
Published: August 2023

Economic growth is usually used as a reference as an indicator of economic success in a region. Such indicators are, for example, problems regarding inflation and unemployment as well as improving public welfare. One of the factors that influence economic growth is the number of labor force and unemployment. From year to year population growth is relatively increasing and it will also affect the growth of the labor force. In urban areas, the growth of the labor force is relatively increasing from year to year. In the city of Pekalongan, there is still an alarming number of unemployed, which is 11.042.00 people in 2020. This study aims to determine the effect of economic growth and labor force growth on the unemployment rate in the city of Pekalongan. This type of research is descriptive analytical quantitative research. Analytical descriptive quantitative is a technique or method used is descriptive analytical quantitative method, analytical descriptive method is a method that functions to obtain in-depth data. The point is which data contains meaning and can affect the substance of significant research. Data collection was obtained from secondary data taken from the Central Statistics Agency of Pekalongan City. Based on the results of this study, the level of the labor force and unemployment will also affect the level of economic growth. So that the data obtained from BPS is certainly valid, so it can be concluded that economic growth in Pekalongan City is relatively low, because based on data from BPS Pekalongan City, the number of labor force and unemployment is still relatively high.
Building Civilization in the Era of Science-Based Globalization & Da'wah
Authors: Mujiadi Mujiadi
Published: August 2023

History has been a witness, that the existence and absence of knowledge became the benchmark for the glory and fall of a nation. Science is the light of man, the light of his intellect, the generator of civilization, the bringer of happiness. But science doesn't come by itself. It must be sought, studied, pursued, lived and practiced as well as accounted for truthfully. This is the basis for building civilization, namely by making science the largest part of building a civilization. The development and change of an era is a characteristic of the development of human life from one side because of science and education. However, to become a civilization, of course, ethical aspects and noble morals must be conditions that greatly affect the progress of a society. This paper was prepared by utilizing library facilities as a means for collecting primary and secondary source data. The preparation procedure goes through four stages that must be fulfilled in conducting research, namely heuristics, criticism, interpretation, and historiography. The data sources used are written sources which include books, journals and internet sources. The culture of science is an initial prerequisite and an important thing for the glory of a person and a nation. An individual or a nation that has power or wealth that is not maintained let alone developed without a good culture of knowledge, then later he will depend on other people or nations who are more knowledgeable. Speaking of science, of course the concept of science in Islam is different from the concept of science understood in the Western view. So that errors in understanding the concept of science can cause differences in perception of science. The destruction of Western civilization is obviously very dangerous for human survival. Westernization or liberalization becomes a disease for civilization. So the solution to the salvation of human civilization is to jump-start Islamic civilization. A civilization built with the concept of science in Islam. Building a civilization based on science must be an Islamic intellectual tradition, in fact science is the foundation of the structure of the concept of building Islamic civilization. The continuity of this intellectual or scientific tradition cannot be separated from the contribution of scholars in the past in preserving and spreading these sciences. Their contribution to Islamic science actually began since the Prophet Muhammad SAW received a revelation, which was then conveyed to the Companions, so that the revelation conveyed contained the foundations of pure Islamic scholarship.
Electric School Bus Initiative Advocacy Stakeholder Analysis: A Baseline Report
Authors: Curran Alyssa , Brown Charles T.
Published: August 2023

This working paper focuses on the baseline advocacy stakeholder analysis of U.S.-based environmental, health, disability, and tribal rights and justice representatives. The publication provides highlights from stakeholder interviews, discusses insights from those interviews and provides recommendations to guide the next stages of the Electric School Bus Initiative's work.
PERAN BAHASA INDONESIA DALAM PEMBELAJARAN FISIKA
Authors: Rifa’i Ahmad , Febriani Gani , Rizkyanfi Mochamad Whilky , Aida Siti Nur
Published: August 2023

Bahasa Indonesia selain digunakan sebagai alat komunikasi, bahasa Indonesia juga digunakan untuk meningkatkan kompeten sumber daya manusia. Sumber daya manusia yang berkualitas dapat dicapai dengan cara mengoptimalkan serangkaian proses pembelajaran fisika dalam mencapai tujuan pembelajaran di sekolah. Untuk mencapai tujuan pembelajaran fisika yang diharapakan, maka diperlukan keterampilan berbahasa, keterampilan menggunakan bahasa sesuai dengan ketentuan bertujuan untuk mempermudah memahami ilmu pengetahuan. Ketepatan berbahasa merupakan salah satu keterampilan dalam menggunakan bahasa. Apabila penggunaan bahasa dalam proses pembelajaran fisika di dalam kelas kurang tepat,akan menimbulkan mispersepsi peserta didik dalam menyerap konsep fisika yang dijelaskan oleh pembimbing. Jika hal ini tidak mampu dihindari, akan menimbulkan miskonsepsi dalam kegiatan transfer pengetahuan. Di dalam artikel ini untuk mengetahui betapa pentingnya peran bahasa Indonesia di dalam pembelajaran fisika maka dilakukan sebuah penelitian kuantitatif menggunakan metode kuesioner, yang mana kuesioner ini memuat tiga pertanyaan dan diberikan kepada tiga puluh orang responden dari berbagai jenjang pendidikan. Berdasarkan hasil peneltian tersebut, membuktikan bahwa peran bahasa Indonesia sangat penting dalam proses pembelajaran fisika. Mengingat proses pembelajaran berkaitan dengan interaksi antara pembimbing dan peserta didik melalui bahasa. Kata kunci : bahasa Indonesia, pembelajaran fisika, sumber daya manusia
Surrounded by Ancestors
Authors: Jauernig Jakub , Uchytilová Barbora
Published: August 2023

The ruling dynasties quite literally surrounded themselves with their ancestors (real ones, as well as imaginary ones), creating galleries of their predecessors or artifacts, such as scrolls with genealogical diagrams. A lineage represented in such a manner could then be displayed not only for the royal family but also for their courtiers and foreign diplomats, reminding everyone of the position of the depicted dynasty in contemporary political struggles and in the history of Christianity. This argument is underlined by the fact that within the portrayal of the family, the prophecies of the end of the world and the approach of the Kingdom of Heaven were included as well.

The paper examines how the members of two great European dynasties (Luxembourg and Plantagenet) used pedigrees, which real members they emphasized in them, and which imaginary characters they incorporated into their lineage. Two presented case studies consist of an ancestral gallery of Luxembourg from Karlštejn Castle and a pedigree scroll of Edward IV from the Plantagenet dynasty. This project aims to evaluate the material from geographically distant areas and to look for common features of pedigree construction strategies.
The “Slovak Buddenbrooks”
Authors: Holec Roman
Published: August 2023

Rich banks and rich businesspeople were and still are the showcase of every nation, and the titular business-oriented families combined doing business with the tools of economic nationalism, as well as their love for art with the support of Slovak and Czech painters. The behaviour of the Slovak business elites of rural origin and from smaller towns was influenced by various stimuli (the example of contemporary cities, the way of life and behavioural strategy of the nobility, foreign influence, and the wish to obtain noble status), and they obtained a civic character only gradually. The most important Slovak family banking and business house was created by members of the Makovický family. The Makovický family financially supported the national movement and all the Slovak national societies, too. On the other hand, no public activity, according to the Makovický family, could produce a loss. It was unclear where ethical idealism and material altruism began and ended.One part of the current text explores the original business philosophies of two prominent individuals who are often associated with the families: Slovak Ján Pálka (a member of the tanning dynasty) and the famous world-class Moravian manufacturer Tomáš Baťa. Although they were both involved in leather processing, their environments were characterised by different cultures, traditions and opportunities. Jan Pálka drew on various socio-philosophical and Utopian sources and relied on idealistic principles. In the spirit of economic nationalism, he strove to incentivise his workers to increase production efficiency by sharing the ownership of his factory and its profits in his own and the national collective interest. He went bankrupt and was, along with his theoretical model, relegated to the role of an admired visionary. In contrast, Tomáš Baťa was inspired by the American experience and the ideological impulses of Italian fascism. Even by 1914, he had pragmatically abandoned the use of all tools of economic nationalism and attempted to get as many state commissions as possible. The continuity of many similar businesses and their representatives was either disrupted by the totalitarian decisions of the powerful during World War II or shortly after at the hands of the Communists.
“Erased from the Face of God”
Authors: Smiljanić Ivan
Published: August 2023

The paper looks into how influential the ideology of economic nationalism was in Slovene lands and in what contexts it appeared. This is explored through a case study of an entrepreneur and landowner, Anton Kajfež, and his sons, owners of one of the largest Slovene companies in Kočevje (Gottschee) before World War I and in the interwar period. The company focused primarily on timber trade and became a significant shareholder in many regional companies and banks. Kajfež was a promoter of the local Slovene economy and used his wealth to strengthen it with a series of projects designed to attract Slovene labour, with the goal of overtaking the influence of the Gottscheers, a local group of German origin. The Kajfež family ran up a deficit of several million dinars, so bankruptcy had to be declared in 1928. Because of the close ties the Kajfež company established in the region, the collapse was a major blow to the entire local Slovene economy and politics. The Gottscheers celebrated the company’s demise and its negative impact on Slovenes. The affair is an example of a late interwar national struggle between Slovenes and Germans, much more common in the Austro–Hungarian period.
ANALYSIS OF NVA WASTE IN PT "XYZ" WAREHOUSE BUILDING PROJECT, WEST JAVA, INDONESIA
Authors:   Muhammadiyah Jakarta University, Nurlaelah Nurlaelah
Published: August 2023

Currently, construction waste remains a major concern for researchers and construction practitioners. Various efforts have been made to minimize waste during construction, aiming not only for the benefit of owners and contractors but also for the sustainable environment. Therefore, this research attempts to discuss construction waste related to Non-Value Added Activities (NVA) waste in the PT "XYZ" warehouse building project. The final results indicate the presence of 7 types of NVA waste along with various examples, and the most frequent occurrence is waste related to waiting.
Slipped Bilateral Capital Femoral Epiphysis in a Patient Older Than 25 Case Report
Authors:   Universidad de la República, School of Medicine, Montevideo, Uruguay 2023, Davyt Dr. J. , Sosa Dr. M. ,   Universidad de la República, School of Medicine, Montevideo, Uruguay 2023, Rey Dr. R ,   Clinic of Traumatology and Orthopedics,, Universidad de la República, School of Medicine, Montevideo, Uruguay 2023, Lemus Dr. E. ,   Universidad de la República, School of Medicine, Montevideo, Uruguay 2023, Agüero Dr. P. ,   Universidad de la República, School of Medicine, Montevideo, Uruguay 2023, Mendoza Prof. Dr. Beatriz ,   Clinic of Endocrinology and Metabolism, Universidad de la República, School of Medicine, Montevideo, Uruguay 2023
Published: August 2023

The slipped capital femoral epiphysis is the most frequent lesion of the hip in children between the ages of 8 and 15. They are classified according to the stability of the physis in stable and unstable. This pathology needs to be quickly diagnosed and treated due to its consequences. Several predisposing factors have been identified including endocrinological pathologies and genetic disorders. It is a pathology that is extremely rare in people older than 18 years of age. The Kallmann Syndrome is the association of congenital hypogonadotropic hypogonadism (CHh) a strange disorder caused by the deficient production, secretion or action of the Gonadotropin-releasing hormone (GnRH) and deficient sense of smell (anosmia or hyposmia)
Legal Review Regarding the Designation of Papuan Armed Criminal Groups as Terrorists in the Perspective of International Criminal Law
Authors:   Master of Law, Diponegoro University, Jl. Imam Bardjo, SH No. 1-3 Pleburan UNDIP Campus, Semarang 50241, Indonesia, Prabayani Hilda , Setiyono Joko ,   Master of Law, Diponegoro University, Jl. Imam Bardjo, SH No. 1-3 Pleburan UNDIP Campus, Semarang 50241, Indonesia
Published: August 2023

The Papuan Armed Criminal Group has been officially designated as a terrorist organization on April 29, 2021 by referring to the Law of the Republic of Indonesia Number 5 of 2018 concerning Amendments to Law Number 15 of 2003 concerning the Stipulation of Government Regulations in Lieu of Law Number 1 of 2002 Concerning the Eradication of Criminal Acts of Terrorism Becomes Law by the Indonesian government. This is thought to have caused the conflicts and tensions that have been occurring in Papua to continue to escalate until early 2023, to be precise, after the determination was made. The designation as a Terrorism organization certainly has an effect related to its status according to the provisions of International Criminal Law. In international criminal law, the status of the Papuan armed criminal group after being designated as terrorists has the same consequences when this group is referred to as KKB (Armed Criminal Group). His actions do not include international crimes that fall under the criminal jurisdiction of the International Criminal Court (ICC) as regulated in the 1998 Rome Statute, however, terrorism crimes can be tried by the ICC if a terrorism case meets the requirements of an international crime. This research method uses a normative juridical method where the research is carried out by examining literature and secondary data, doctrines and principles in the science of law. The approach used in this research is a literature study which includes Primary Legal Materials, Secondary Legal Materials, and Tertiary Legal Materials. To support secondary material, data was obtained from documents or research journals regarding the Papuan KKB case.
estudos jusliterários e a humanização do direito
Authors: Alves Míriam Coutinho de Faria , Santos Carlos Alberto Ferreira dos , Santos Márcio dos
Published: August 2023

Este artigo visa refletir sobre a importância das pesquisas jusliterárias para humanização do Direito. Busca trazer para análise elementos conceituais do campo dos estudos jusliterários no intuito de compreender a pesquisa jusliterária como aporte necessário para o viés humanizador da experiência jurídica. Esta análise interdisciplinar de caráter fenomenológico e dialético dialoga com perspectivas da metodologia etnográfica através da construção jusliterária de autores como José Calvo González e Luiz Alberto Warat que fomentaram a importância da cultura literária do direito como via humanizadora da ciência jurídica. Como resultado, observa-se como a humanização através dos estudos jusliterários ampliam as condições hermenêuticas do direito através da prática do jurista leitor.
Experiências autoetnográficas na educação literária em língua inglesa
Authors: Tiraboschi Fernanda Franco
Published: August 2023

Este artigo problematiza as potencialidades e limitações de aulas, envolvendo a leitura colaborativa de textos literários em inglês produzidos por mulheres de grupos não-hegemônicos. O referencial teórico é constituído por estudos sobre educação literária nas perspectivas decoloniais e colaborativas. A materialidade empírica deste estudo autoetnográfico é construída pelas interações em sala de aula, entrevistas com seis participantes e um diário reflexivo escrito pela professora da turma. As discussões apontaram para a permanência de colonialidades na relação professora e alunas/os, de modo a evidenciar a visão, por parte das/os aprendizes, de professora/professor como a/o detentora/detentor do saber literário.
Catando coisas com Carolina Maria de Jesus
Authors: Carvalho Rafael Manfrinatto de , Oliveira Junior Wenceslao Machado de
Published: August 2023

O artigo aproxima a autoetnografia de uma pesquisa sobre Quarto de despejo, livro de Carolina Maria de Jesus, misturando dois tipos de escrita: uma por coautoria – mestrando e seu orientador – onde um vislumbre do projeto é apresentado; outra de criação pessoal, relacionada à história de vida do pesquisador, em meio à de mulheres periféricas trabalhadoras domésticas. Essas experiências confundem-se num fluxo pós-colonial em que parte da investigação se dá no próprio ato da escrita, relatando o recente encontro com o campo conceitual autoentográfico, além de outras características desse estudo que tem o êxodo como própria metodologia.
Efetividade da acupuntura auricular no tratamento da depressão, ansiedade e estresse em profissionais da atenção primária à saúde durante a pandemia da Covid-19
Authors:   , Andrade Luiza Agostini
Published: August 2023

Este estudo teve por objetivo avaliar a efetividade da acupuntura auricular no tratamento da depressão, ansiedade e estresse em profissionais da Atenção Primária à Saúde, atuantes durante a pandemia da COVID-19. Trata-se de um estudo quase experimental realizado em duas etapas. Na primeira etapa (n = 162), foi verificado o perfil sociodemográfico e clínico dos participantes, utilizando questionário contendo as variáveis de interesse do estudo, e mapeada a prevalência dos níveis de depressão, ansiedade e estresse na população estudada com auxílio da escala Depression, Anxiety and Stress Scale (DASS-21). Na segunda etapa (n = 29), foi verificado o efeito da acupuntura auricular nos níveis de depressão, ansiedade e estresse, e no cortisol salivar, nos profissionais identificados com níveis de ansiedade moderado ou superior na primeira etapa do estudo. Utilizou-se um protocolo de acupuntura auricular semanal, nos pontos Shenmen, Rim, Sistema Nervoso Simpático, Coração, Tronco Cerebral, Yang do Fígado 1, Yang do Fígado 2, Pulmão e Baço. Os dados foram analisados utilizando estatística descritiva e inferencial, considerando um nível de significância de 5%. Dos 162 participantes, 11,7% tiveram níveis de depressão, ansiedade e estresse moderado ou superior; 26,5% apresentaram ansiedade moderada ou superior; 19,8% expressaram estresse moderado ou superior; e 17,3% manifestaram depressão moderada ou superior. Sexo feminino, menor renda familiar, menor nível de escolaridade, diagnósticos prévios de ansiedade, depressão e/ou Síndrome de Burnout, não realização de atividade física, uso de medicações ansiolíticas e/ou antidepressivas, e acompanhamento psicológico e/ou psiquiátrico foram associados a maiores níveis de depressão, ansiedade e/ou estresse. Constatou-se que a acupuntura auricular reduziu os níveis de depressão (p=0,000), ansiedade (p=0,000) e estresse (p=0,000) dos profissionais, evidenciando sua efetividade para o tratamento destes transtornos mentais. Já os níveis de cortisol manhã (p=0,011) e noite (p=0,010) apresentaram leve aumento após a intervenção. Os achados evidenciaram a importância de ações voltadas à promoção da saúde mental dos profissionais que atuam neste nível de atenção à saúde. A acupuntura auricular foi efetiva para reduzir os níveis de depressão, ansiedade e estresse, e pode ser utilizada para potencializar o tratamento destas condições, bem como para a promoção da saúde mental destes trabalhadores. Palavras-chave: Saúde Mental. Acupuntura Auricular. Ansiedade. Depressão. Atenção Primária à Saúde. Estresse Psicológico.
Fasting Plasma Glucose May İnitially Behave as a Positive But Eventually Negative Acute Phase Reactant in The Body
Authors:   MD, Specialist of Internal Medicine, Medical Faculty of the Mustafa Kemal University, Turkey, Rami Helvaci Mehmet
Published: August 2023

Background: Smoking may cause a low-grade inflammation on vascular endothelium terminating with an accelerated atherosclerosis-induced end-organ insufficiencies. Plasma triglycerides may be positive acute phase reactants (APRs) whereas fasting plasma glucose (FPG) negative APR indicating the inflammatory effects of smoking. Method: Consecutive patients with irritable bowel syndrome (IBS) and age and sex-matched control cases were included. IBS was diagnosed according to Rome II criteria in the absence of red flag symptoms including pain, nocturnal diarrhea, weight loss, fever, or any abnormal finding of the physical examination.
Role of Hypertension and Obesity as Risk Factors for IHD
Authors:   Balkh University, Afghanistan, Balkh, Ghaffari Mohammad Mujtaba Ghaffari
Published: August 2023

Background: Hypertension and obesity are two major modifiable risk factors for CAD, most of the time there will be more than two risk factors in an IHD. Obesity itself cause insulin resistance to initiate type -2 DM. is the most common and significant RFs for IHD, and proper BP management is the cornerstone of both direct and indirect prevention. Overweight and obesity account for more than 80% of CHD patients. Obesity is sometimes viewed as a “minor” CHD RF, however it is a widely effective risk-factor approach. A range of “major” risk factors have been proven to be significantly influenced by weight loss, including HTN, hyperlipidemia and insulin resistance/T2DM.
Implementasi Kebijakan Publik tentang Model Pengurangan Resiko Bencana dengan Pendekatan Pada Masyarakat Dalam Program Desa Tahan Bencana Di Daerah Istimewa Yogyakarta
Authors: Juliswara Vibriza , Manik Rusman Rupinus , Karnadjaja Djuniawan
Published: August 2023

The increase in disasters in Indonesia from year to year worries the government and people in disaster-prone areas. For this reason, BNPB (National Disaster Management Agency) launched a community-based program, namely Destana (Disaster Resistant Village) which is implemented by the Regional Disaster Management Agency (BPBD) Special Region of Yogyakarta through public policy. This research focuses on the implementation of the Destana program. The data collection methods were conducted through interviews and narrative question and answer. The results of the research, BPBD DIY has succeeded in forming 243 Destana which are spread across four disctricts and one city of DIY, the community is involved in identifying potential disasters in their area, taking preventive measures, being aware of the impact of disasters and how to deal with them, education, and forming volunteer groups. Conclusion, the Destana program in DIY was implemented by increasing public awareness, the ability to deal with disaster threats and being proactive, participatory and organized as an indication that the implementation of public policy in DIY in reducing disaster risk can be used as a model to reduce the impact of disasters in other regions
A Comparison of Internal Jugular versus Subclavian Vein Approaches in Totally Implanted Venous Access Ports
Authors: DÖKDÖK Murat , KARAMAN Kutlay , YUCEL Aysen
Published: August 2023

The purpose of this study was to retrospectively review the outcome and complications of totally implantable venous-access ports (TIVAPs) inserted via low internal jugular vein (IJV) approach under ultrasound guidance versus subclavian vein (SCV) approach.304 cancer patients who could be followed up to the time of catheter removal or to the end of the study period were enrolled in the study. 200patients had the placement of TIVAPs via IJV and 104 patients via SCV. Statistical analysis showed that there were no differences with regard to the patient characteristics and to the site of primary malignancy in two groups, while the large majority of the TIVAPs had been inserted in the right side. The average port dwelling time was higher in the IJV group compared to the SCV group, the difference was statistically significant (p<0.001). Complications were more frequent in the SCV than in the IJV approach (12 patients vs. 3 patients). Our analysis revealed that TIVAP is a safe and effective route for long-term administration of chemotherapy, and the placement of TIVAPs via the right IJV is associated with a low long-term complication rate.
PC-3 İnsan Prostat Kanseri Hücrelerinde Fenforminin Hücre Canlılığı ve FGFR2 Ekspresyonu Üzerine Etkileri
Authors: ÇETİNAVCI Dilan , ÖZGÜL ÖNAL Melike , YİĞİTTÜRK Gürkan , YAŞAR Volkan , ELBE Hülya , ÖZTÜRK Feral
Published: August 2023

Prostat kanseri, erkeklerde kansere bağlı ölümlerin ikinci en sık nedenidir. Kemoterapötiklere direnç gelişmesi nedeniyle prostat kanserini tedavi etmek için yeni ilaçlara ihtiyaç vardır. Fenformin biguanid grubu antidiyabetik bir ilaçtır ve antikanserojen etkileri de vardır. Fibroblast büyüme faktörü reseptörü 2 (FGFR2), hücre proliferasyonunu ve farklılaşmasını destekleyen bir membran reseptörüdür. Çalışmamızda; PC-3 insan prostat kanseri hücrelerinde fenforminin FGFR2 üzerinden etkilerinin araştırılması amaçlandı. Deney grupları; kontrol grubu, 1 mM, 2 mM, 5 mM ve 10 mM fenformin uygulanan gruplar idi. Fenformin uygulamalarından 24 saat sonra WST-1 hücre canlılığı analizi yapıldı, ayrıca FGFR2 için immunositokimyasal boyamadan sonra H-Skoru hesaplandı. İstatistiksel analizler için SPSS programı kullanıldı. WST-1 analizi sonuçlarına göre; kontrol grubu ile 5 mM fenformin grubu, kontrol grubu ile 10 mM fenformin grubu ve 1 mM fenformin grubu ile 10 mM fenformin grubu karşılaştırıldığında hücre canlılığında istatistiksel olarak anlamlı derecede azalma tespit edildi (p<0.05, hepsi için). H-Skoru sonuçlarına göre; kontrol grubu ve 5 mM fenformin grubu, kontrol grubu ile 10 mM fenformin grubu, 1 mM fenformin grubu ile 5 mM fenformin grubu ve 1 mM fenformin grubu ile 10 mM fenformin grubu arasındaki FGFR2 ekspresyonunun azalması istatistiksel olarak anlamlıydı (p<0.05, hepsi için). Çalışmamızda fenformin, doza bağlı olarak PC-3 insan prostat kanseri hücreleri üzerinde FGFR2 ekspresyonunu azaltıcı ve hücre proliferasyonunu inhibe edici etkiler göstermiştir. En etkili dozun 10 mM fenformin olduğu tespit edilmiştir.
Immediate Frontal Nerve Repair Produces Early Facial Reanimation: A Case Report and Literature Review
Authors: ALTIPARMAK Mehmet , ALATAŞ Ömer Doğan
Published: August 2023

Frontal nerve injury may result with permanent facial asymmetry. This may severely affect social and psychological status. It is known that early repair of frontal nerve is more effective than delayed repair. However, it is not well defined how the frontal nerve repairment responds to emergency coaptation. A case report of a 27 years old male whom had a right frontotemporal laceration after a trauma has been presented. The patient was operated immediately and the frontal nerve was explored under microscope. Either ends of the frontal nerve were found within the injury zone and repaired. Frontal muscle reanimation started after one week and recorded to be nearly fully gained in post-operative one month. House-Brackmann Grade VI injuryimprovedto a Grade II nervefuncitonwithin 1 monthafteroperation. In conclusion, emergency coaptation of frontal nerve injuries may result with full reanimation of the muscle.
Effects of Different Ozone Doses Added to the Antibiotic Treatment on Cytokine Levels in Experimental Sepsis Model
Authors: TÜFEKÇİ Hamdi , GÜVEN Bülent Barış , BİÇERER Enis , DERE Kamer , ÖZKAN Sezai , DAĞLI Güner
Published: August 2023

We aimed to examine the changes caused by ozone therapy added to the antibiotic treatment on proinflammatory and anti-inflammatory cytokine levels in an experimental sepsis model formed with E. coli endotoxin. Rats were divided into 6 groups of 10 rats. Sepsis was formed by dosing 5 groups of rats with intraperitoneal E. coli endotoxin injection. For the first 3 groups, 0.6 mg/kg, 0.9 mg/kg, and 1.1 mg/kg doses of ozone therapy were added to the antibiotic treatment and group-4 only received antibiotic treatment. Group-5 was not treated. Group-6 received intraperitoneal serum physiologic injection simultaneously with the other groups. All treatments were sustained for 5 days. IL-1, IL-10, and TNF-alpha levels were detected in blood serum taken from rats sacrificed on day 6. It was seen that IL-1, TNF-alpha levels are significantly lower than the levels in other groups that received ozone therapy. In the comparisons amongst the groups receiving ozone therapy, it was observed that IL-1 levels do not have a significant difference and TNF-alpha levels are significantly lower in the two groups receiving lower doses than the group receiving a higher dose. There were no significant differences detected between groups at serum levels of IL-10 which is an anti-inflammatory cytokine. It was concluded that ozone added to the antibiotic treatment in sepsis could have a positive effect on survival rates by suppressing inflammatory process.
Bir Merkeze Başvuran Çocukluk Çağı Brusellozu Tanısı Konulan Hastaların Demografik, Hematolojik ve Laboratuvar Bulgularının İncelenmesi
Authors: KILIÇ ÇİL Merve , ÇİL Metin
Published: August 2023

Enfekte hayvanlardan ve ürünlerinden insanlara bulaşan bruselloz, ülkemizde ve tüm dünyada halen yaygın olarak görülen zoonotik bir enfeksiyondur. Çalışmamızda tek merkeze başvuran pediatrik bruselloz vakalarının demografik özellikleri, hematolojik ve laboratuvar anormalliklerinin değerlendirilmesi amaçlanmıştır. Bu çalışmada Haziran 2020 ile Haziran 2021 tarihleri arasında bruselloz nedeni ile takip edilen 47 çocuk hasta retrospektif olarak incelenmiştir. Çalışmamızdaki 47 hastanın 23 (%48.9)’ü erkek, 24 (%51.1)’ü kızdı ve yaş ortalaması 9.96 ± 4.26 (1.3-17.5 yaş) idi. Hastaların %48.9’u kırsalda yaşıyordu, 37 (%78.7)’sinde çiğ süt veya süt ürünü tüketim öyküsü vardı. Hastaların %44.7’sinde ise hanede benzer hastalık öyküsü mevcuttu. Başvuru şikayetlerine bakıldığında; en sık başvuru şikayetleri ateş, kas-eklem ağrısı ve halsizlikti. Kas ve eklem ağrısı olan 20 hastadan (%42.6) beş tanesinin artriti vardı (%10.6), en sık tutulan eklem dizdi (%6.4). En sık saptanan fizik muayene bulgusu ateş idi (%12.8). Hastaların %57.4‘ünde en az bir seride hematolojik tutulum gözlendi. En yaygın hematolojik bulgu anemiydi (%46.8). Dörder hastada trombositopeni ve lökopeni tespit edildi (%8.5). Hastaların üçünde bisitopeni (%6.4), birisinde ise pansitopeni gözlendi (%2.1). Brucella aglütinasyon testleri olguların tamamında pozitifti. Kan kültürü pozitiflik oranı %12.8 idi. Hastaların %21.3’ü hastaneye yatırılarak takip edildi. Tüm hastalara kombine tedavi verildi. Tedavi ilişkili yan etki gözlenmedi. Bir hastada relaps görülürken, mortalite saptanmadı. Bruselloz, klinik bulgularının özgül olmaması, komplikasyonlarının fazla olması ve geniş kitleleri etkileyebilmesi nedeniyle halen ülkemizde önemli bir sağlık sorunu olmaya devam etmektedir. Hematolojik bulgularda bozulma da görülebilmesi nedeniyle endemik bölgede yaşayan hastalarda sitopeninin ayırıcı tanısında bruselloz mutlaka akılda tutulmalıdır.