bluuebunny/crossref_metadata_2025 huggingface dataset:
Site-specific nonenzymatic peptide S/O–glutamylation reveals the extent of substrate promiscuity in glutamate elimination domains
Authors: Vinogradov Alexander , Goto Yuki , Suga Hiroaki
Published: February 2022

Formation of dehydroalanine and dehydrobutyrine residues via tRNA-dependent dehydration of serine and threonine is a key post-translational modification in the biosynthesis of lanthipeptides and thiopeptides. The dehydration process involves two reactions, wherein the O–glutamyl Ser/Thr intermediate, accessed by a dedicated enzyme utilizing Glu-tRNAGlu as the acyl donor, is recognized by the second enzyme, referred to as the glutamate elimination domain (ED), which catalyses the eponymous reaction yielding a dehydroamino acid. Here, we report two complementary strategies based on a thiol-thioester exchange reaction for direct, nonenzymatic access to diverse ED substrates. These chemistries enabled us to dissect the substrate recognition requirements of three known EDs. Our results establish that EDs are uniquely promiscuous enzymes capable of acting on substrates with arbitrary amino acid sequences, and performing retro-Michael reaction beyond the canonical glutamate elimination. To aid in the substrate recruitment process, EDs apparently engage in nonspecific hydrophobic interactions with their substrates.
Improved photodecarboxylation properties in zinc photocages constructed using m-nitrophenylacetic acid variants
Authors: Shigemoto Austin , Bhattacharjee Avik , Hickey Erin , Boyd Hallee , McCormick Theresa , Burdette Shawn
Published: February 2022

The methoxy- and fluoro-derivatives of meta-nitrophenylacetic acid (mNPA) chromophores undergo photodecarboxylation with comparable quantum yields to unsubstituted mNPA, but uncage at red-shifted excitation wavelengths. This observation prompted us to investigate DPAdeCageOMe (2-[bis(pyridin-2-ylmethyl)amino]-2-(4-methoxy-3-nitrophenyl)acetic acid) and DPAdeCageF (2-[bis(pyridin-2-ylmethyl)amino]-2-(4-fluoro-3-nitrophenyl)acetic acid) as Zn2+ photocages. DPAdeCageOMe has a high quantum yield and exhibits other photophysical properties comparable to XDPAdeCage ({bis[(2-pyridyl)methyl]amino}(9-oxo-2-xanthenyl) acetic acid), the best perforiming Zn2+ photocage reported to date. Since the synthesis of DPAdeCageOMe is more straightforward than XDPACage, the new photocage will be a highly competitive tool for biological applications.
A response surface model to predict and experimentally tune the chemical, magnetic and optoelectronic properties of oxygen-doped boron nitride
Authors: Shankar Ravi , Mistry Elan , Lubert-Perquel Daphne , Nevjestic Irena , Heutz Sandrine , Petit Camille
Published: February 2022

A new material platform for boron nitride (BN) as a heterogeneous photocatalyst for solar fuels synthesis has recently emerged. One of the bottlenecks of this material is the lack of photoactivity under visible light, which hinders its rate performance. Theoretical studies have predicted that tuning the oxygen content in oxygen-doped BN (BNO) might be used to lower and vary the band gap. However, this is yet to be verified experimentally. We present herein a systematic experimental route facilitating simultaneous tuning of the chemical, magnetic and optoelectronic properties of BNO using a multivariate synthesis parameter space. Deep visible range band gaps (1.50 – 2.90 eV) were experimentally achieved and tuned over an oxygen composition of 2 – 14 at. %, and specific paramagnetic OB3 content of 7 – 294 a.u. g-1, thus supporting theoretical predictions. Through designing a response surface via a design of experiments (DOE) process, the key synthesis parameters influencing the chemical, magnetic and optoelectronic properties of BNO were identified. In addition, model prediction equations relating the aforementioned properties to the synthesis parameter space are presented. Accurate model predictions for the oxygen content and band gap were conducted and validated experimentally. Such a methodology is valuable for further advances in tailoring and optimising BN materials for heterogeneous photocatalytic reactions.
Carbodiphosphorane-Catalyzed Hydroboration of Ketones and Imines
Authors: Aversa-Fleener Cara , Chang Daniel , Liberman-Martin Allegra
Published: February 2022

We report the use of a cyclic carbodiphosphorane catalyst for ketone and imine hydroboration reactions. To our knowledge, this represents the first use of a carbodiphosphorane as an organocatalyst. The carbodiphospohorane shows superior catalytic activity compared to other neutral carbon nucleophiles tested.
Site-Specific DNA Functionalization through the Tetrazene-Forming Reaction in Ionic Liquids
Authors: Ishizawa Seiya , Tumurkhuu Munkhtuya , Gross Elizabeth , Ohata Jun
Published: February 2022

Development of multiple chemical tools for deoxynucleic acid (DNA) labeling has facilitated wide use of their functionalized conjugates, but significant practical and methodological challenges remain to achievement of site-specific chemical modification of the biomacromolecule. As covalent labeling processes are more challenging in aqueous solution, use of nonaqueous, biomolecule-compatible solvents such as an ionic liquid consisting of a salt with organic molecule architecture, could be remarkably helpful in this connection. Herein, we demonstrate site-specific chemical modification of DNAs through a tetrazene-forming amine-azide coupling reaction using an ionic liquid. This ionic liquid-enhanced reaction process has good functional group tolerance and precise chemoselectivity, and enables incorporation into DNA of various useful functionalities such as biotin, cholesterol and fluorophores which could be incorporated into DNA through this method. A site-specifically labeled single stranded nucleotide, or aptamer interacting with a growth factor receptor (Her2) was successfully used in the fluorescence imaging of breast cancer cell lines. The non-traditional medium-promoted labeling strategy described here provides an alternative design paradigm for future development of chemical tools for applications involving DNA functionalization.
A “Shake ‘n Bake Route” to Functionalised Zr-UiO-66 Metal-Organic Frameworks
Authors: D'Amato Roberto , Bondi Roberto , Moghdad Intissar , Costantino Ferdinando , Marmottini Fabio , J. McPherson Matthew , Naili Houcine , Taddei Marco
Published: February 2022

We report a novel synthetic procedure for the high-yield synthesis of metal-organic frameworks with UiO-66 topology starting from a range of commercial ZrIV precursors and various substituted dicarboxylic linkers. The syntheses are carried out by grinding in a ball mill the starting reagents, namely Zr salts and the dicarboxylic linkers, in the presence of a small amount of acetic acid and water (1 mL total volume for 1 mmol of each reagent), followed by incubation at either room temperature or 120 °C. Such a “shake ‘n bake” procedure avoids the use of large amounts of solvents generally used for the syntheses of Zr-MOF. Acidity of the linkers and the amount of water are found to be crucial factors in affording materials of quality comparable to that of products obtained in solvo- or hydrothermal conditions.
Molecular Dynamics Simulations of the Breathing Phase Transition of MOF Nanocrystallites II: Explicitly Modeling the Pressure Medium
Authors: Schaper Larissa , Keupp Julian , Schmid Rochus
Published: February 2022

One of the most investigated properties of porous crystalline metal-organic frameworks (MOFs) is their potential flexibility to undergo large changes in unit cell size upon guest adsorption or other stimuli, referred to as ”breathing”. Computationally, such phase transitions are usually investigated using periodic boundary conditions, where the system’s volume can be controlled directly. However, we have recently shown that important aspects like the formation of a moving interface between the open and the closed pore form or the free energy barrier of the first-order phase transition and its size effects can best be investigated using non-periodic nanocrystallite (NC) models [Keupp and Schmid (2019) Adv. Theory Simul. 2, 1900117]. In this case, the application of pressure is not straightforward, and a distance constraint was used to mimic a mechanical strain enforcing the reaction coordinate. In contrast to this prior work, a mediating particle bath is used here to exert an isotropic hydrostatic pressure on the MOF nanocrystallites. The approach is inspired by the mercury nanoporosimetry used to compress flexible MOF powders. For such a mediating medium, parameters are presented that require a reasonable additional numerical effort and avoid unwanted diffusion of bath particles into the MOF pores. As a proof-of-concept, NCs of pillared-layer MOFs with different linkers and sizes are studied concerning their response to external pressure exerted by the bath. By this approach, an isotropic pressure on the NC can be applied in analogy to corresponding periodic simulations, without any bias for a specific mechanism. This allows a more realistic investigation of the breathing phase transformation of a MOF NC and further bridges the gap between experiment and simulation.
Low Electronic Conductivity of Li7La3Zr2O12 (LLZO) Solid Electrolytes from First Principles
Authors: Squires Alex , Davies Daniel , Kim Sunghyun , Scanlon David , Walsh Aron , Morgan Benjamin
Published: February 2022

Lithium-rich garnets such as Li7La3Zr2O12(LLZO) are promising solid electrolytes with potential application in all-solid-state batteries that use lithium-metal anodes. The practical use of garnet electrolytes, however, is limited by pervasive lithium-dendrite growth, which leads to short-circuiting and cell failure. One possible mechanism for this lithium-dendrite growth is the direct reduction of lithium ions to lithium metal within the electrolyte, and lithium garnets have suggested to be particularly susceptible to this dendrite-growth mechanism due to high electronic conductivities relative to other solid electrolytes [Hanet al. Nature Ener.4187, 2019]. The electronic conductivities of LLZO and other lithium-garnet solid electrolytes, however, are not yet well characterised. Here, we present a general scheme for calculating the intrinsic electronic conductivity of nominally insulating material under variable synthesis conditions from first principles and apply this to the prototypical lithium-garnet LLZO. Our model predicts that under typical battery operating conditions, electron and hole mobilities are low (<1 cm2V−1s−1), and bulk electron and hole carrier concentrations are negligible, irrespective of initial synthesis conditions or dopant levels. These results suggest that the bulk electronic conductivity of LLZOis not sufficiently high to cause bulk lithium-dendrite growth during cell operation, and that any non-negligible electronic conductivity in lithium garnet samples is likely due to extended defects or surface contributions.
Molecularly Engineered PEG-TRAP Conjugates for Platelet Activation and Accelerated Hemostasis
Authors: Qin Xiao-Hua , Chen Jie , Labuda Krystyna , Hruschka Veronika , Liska Robert , Redl Heinz , Slezak Paul
Published: February 2022

Synthetic peptide conjugates that can molecularly target and activate blood platelets are designed for hemostasis applications. An engineered thrombin receptor-activating peptide (TRAP-Cys, SFLLRNPNC) is covalently attached to cell-compatible 8-arm poly (ethylene glycol) maleimides via Michael addition. It is proved that the ability of TRAP to activate platelets is retained in the conjugated form by means of thromboelastometry, platelet aggregation assay and flow cytometry. A 0.5 % PEG-TRAP solution can efficiently activate platelets and shorten the clotting time to ~45 %.
Room-Temperature Reversible Chemisorption of Carbon Monoxide on Nickel(0) Complexes
Authors: Yamauchi Yasuhiro , Hoshimoto Yoichi , Kawakita Takahiro , Kinoshita Takuya , Uetake Yuta , Sakurai Hidehiro , Ogoshi Sensuke
Published: February 2022

Chemisorption on organometallic-based adsorbents is crucial for the controlled separation and long-term storage of gaseous molecules. The formation of covalent bonds between the metal centers in the adsorbents and the targeted gases affects the desorption efficiency, especially when the oxidation state of the metal is low. Herein, we report a pressure-responsive nickel(0)-based system that is able to reversibly chemisorb carbon monoxide (CO) at room temperature. The use of N-heterocyclic carbene ligands with hemi-labile N-phosphine oxide substituents facilitates both the adsorption and desorption of CO on nickel(0) via ligand substitution. Ionic liquids were used as the reaction medium to enhance the desorption rate and establish a reusable system. These results showcase a way for the sustainable chemisorption of CO using a zero-valent transition-metal complex.
MAKNA PEPINDHAN MANUSIA DALAM PANYANDRA UPACARA PANGGIH PENGANTIN ADAT JAWA RAGAM SURAKARTA
Authors: Nardilla Anggyta Aulia Rahma
Published: February 2022

This research discusses the types and meanings of human's pepindhan from  Javanese panyandra wedding ceremony Surakarta’s style in Rejoso Village, Rejoso District, Nganjuk Regency, East Java. The types and the meaning’s theory from pepindhan manusia  of Javanese panyandra wedding ceremony Surakarta’s style in  Rejoso Village in this research comes from Padmosoekotjo, Aloysius, and Halley. This qualitative descriptive study using a stylistic approach method. The object of this research is the utterances from Mr. Sujarwo and Mr. Wasito's speech as a famous Master of Ceremony (MC) in Rejoso Village. Data collected through the observations and analyzed by Miles and Huberman’s analysis. Data’s step analysis from this research through data reduction, presentation data, and verification analysis. Data validity is attempted through triangulation and validity checking. The results of this research indicated that the types of human’s pepindhan were found in the Javanese panyandra wedding ceremony Surakarta’s style in  Rejoso Village, Rejoso District,  Nganjuk Regency, East are similes and metaphors. The meaning of human’s pepindhan in this research means perfection, luxury, glorious, and beauty from the description of the situation, bridesmaids, conditions,  and the good prayers for the household of the bride and groom.Penelitian ini membahas tentang jenis dan makna pepindhan manusia  dalam panyandra upacara panggih pengantin adat Jawa ragam Surakarta di Desa Rejoso, Nganjuk, Jawa Timur. Jenis dan makna pepindhan manusia dalam panyandra upacara panggih pengantin adat Jawa ragam Surakarta di Desa Rejoso pada penelitian ini menggunakan teori dari Padmosoekotjo, Aloysius, dan Halley. Penelitian deskriptif kualitatif ini menggunakan metode pendekatan stilistika. Objek kajian dalam penelitian ini ialah tuturan dari pewara terkenal di Desa Rejoso yaitu Bapak Sujarwo dan Bapak Wasito. Data pada penelitian ini dikumpulkan melalui observasi lapangan dan dianalisis menggunakan analisis data Miles dan Huberman. Tahapan analisis data penelitian ini dilakukan dengan tahap analisis reduksi data, penyajian data, dan verifikasi. Keabsahan data pada penelitian ini menggunakan triangulasi data dan pemeriksaan validitas oleh ahli bidang. Hasil dari penelitian ini menunjukan adanya jenis pepindhan manusia yang ditemukan pada panyandra upacara panggih pengantin  adat Jawa ragam  Surakarta di Desa berupa simile dan metafora. Makna dari pepindhan manusia pada penelitian ini berarti kesempurnan, kemewahan, kesakralan, dan keindahan dari penggambaran keadaan pada  resepsi pernikahan, pengiring pengantin, kondisi acara, dan doa yang baik untuk rumah tangga dari  pengantin.
STRUKTUR SEMANTIS VERBA AKTIVITAS GIGI DALAM BAHASA JAWA: KAJIAN METABAHASA SEMANTIK ALAMI
Authors: Rahardian Ema
Published: February 2022

Javanese teeth activity is interested to be analyzed. It is because the Javanese language has various lexicons to express teeth activity. This paper aims to explore the semantic structure of Javanese teeth activity by using the theory of natural semantic metalanguage (NSM). The data used in this paper are taken from The Bausastra Jawa dictionary as well as data created by the researcher as a native Javanese speaker. The technique of data analysis in this study consists of four steps, namely determining the semantic primitive, deriving meaning, determining polysemy, dan paraphrasing the meaning. The result shows that Javanese teeth activity is realized into 23 lexicons, namely, mamah, ngilut, ngenyoh, nggayem, ngemah, nginang, nggondol, nyakot/nyokot, nggeget, ngeret, ngerot, nyathèk, ngerah, nyekit, nyisil, ngrokot, ngrikit, mbrakot, nglethak, nglethuk, nglethus, ngremus, and nglethik. Its semantic prime is melakukan/terjadi and its semantic component are mengunyah, membawa, menggigit, melepaskan, and mematahkan which is mapped based on the patient and instrumental relation.Verba aktivitas gigi dalam bahasa Jawa merupakan salah satu objek penelitian yang menarik untuk dikaji. Hal itu karena bahasa Jawa memiliki berbagai leksikon untuk mengungkapkan aktivitas gigi. Penelitian ini merupakan penelitian deskriptif kualitatif yang bertujuan untuk mendeskripsikan struktur semantis verba aktivitas gigi dalam bahasa Jawa dengan menggunakan teori metabahasa semantik alami. Data penelitian ini diperoleh dari kamus Bausastra Jawa dan data yang dikreasikan oleh peneliti sebagai penutur asli bahasa Jawa. Teknik analisis data dalam penelitian ini terdiri atas empat langkah, yaitu menentukan makna asali, menderivasi makna, menentukan polisemi, dan memarafrase makna. Hasil penelitian menunjukkan bahwa verba aktivitas gigi direalisasikan dalam 23 leksikon, yaitu mamah, ngilut, ngenyoh, nggayem, ngemah, nginang, nggondol, nyakot/nyokot, nggeget, ngeret, ngerot, nyathèk, ngerah, nyekit, nyisil, ngrokot, ngrikit, mbrakot, nglethak, nglethuk, nglethus, ngremus, dan nglethik. Leksikon-leksikon itu memiliki makna asali melakukan/terjadi dengan komponen semantis mengunyah, membawa, menggigit, melepaskan, dan mematahkan. Komponen semantis itu dipetakan berdasarkan hubungan pasien dan instrumen.
KALIMAT LANGSUNG DAN KALIMAT TIDAK LANGSUNG DALAM WACANA BERITA TERTULIS BERBAHASA INDONESIA
Authors: Isodarus Praptomo Baryadi
Published: February 2022

This article presented the results of research on the elements and functions of direct sentences and indirect sentences in written news discourse in Indonesian. The theory used is the theory of the element of speech and the element of paragraph. This research data is paragraphs containing direct sentences and paragraphs containing indirect sentences in indonesian written news discourse. In this study, observation methods were used for data collection, the method for immediate constituents and the referential identity method for data analysis, and the informal method for presenting the results of data analysis. In Indonesian written news discourse, the direct sentences have a structure: quotations of speech enclosed with double quotes ("..."), commas, actions in the stem that referent 'disclosure', speaker, and (situations of speech). In a direct sentence, the element highlighted is a quote of speech. As a paragraph element, direct sentences tend to serve as developement sentences. Indirect sentences have two types of structures, namely (1) the speaker, the act of speech expressed in the transitive active verbs that referent to 'disclosure', (bahwa, comma), and quotations of speech that are not enclosed with quotation marks; (2) menurut speaker, the quote is not enclosed in quotation marks. In indirect sentences, the highlight is the speaker. As a paragraph element, indirect sentences tend to serve as topic sentences.Dalam artikel ini disajikan hasil penelitian tentang unsur dan fungsi kalimat langsung dan kalimat tidak langsung dalam wacana berita tertulis berbahasa Indonesia. Teori yang digunakan adalah teori tentang unsur tuturan dan unsur pembentuk paragraf. Data penelitian ini adalah paragraf yang mengandung kalimat langsung dan paragraf yang mengandung kalimat tidak langsung dalam wacana berita tertulis berbahasa Indonesia. Dalam penelitian ini digunakan metode simak untuk pengumpulan data, metode bagi unsur langsung dan metode padan referensial untuk analisis data, serta metode informal untuk penyajian hasil analisis data. Kalimat langsung memiliki struktur berupa kutipan tuturan yang diapit dengan tanda kutip ganda (“…”), tanda koma, tindak tutur yang berupa kata asal yang menyatakan makna ‘pengungkapan’, narasumber, dan situasi tindak tutur. Dengan struktur tersebut, kalimat langsung lebih menonjolkan kutipan tuturan. Dalam paragraf, kalimat langsung cenderung berfungsi sebagai kalimat penjelas. Kalimat tidak langsung memiliki dua jenis struktur, yaitu (1) narasumber, tindak tutur yang diungkapkan dalam bentuk verba aktif transitif yang menyatakan makna ‘pengungkapan’ (bahwa atau tanda koma), dan kutipan tuturan yang tidak diapit dengan tanda kutip serta (2) menurut narasumber dan kutipan tuturan yang tidak diapit dengan tanda kutip. Dengan struktur tersebut, kalimat tidak langsung lebih menonjolkan narasumber. Dalam paragraf, kalimat tidak langsung cenderung berfungsi sebagai kalimat topik.
ANALISIS STRUKTUR DAN FUNGSI TEKS IKLAN LAYANAN MASYARAKAT
Authors: Sukesti Restu
Published: February 2022

Public service advertisements (PSA) as a means of communication "govern" to the public even though the form of commanding is in the form of orders, prohibitions, appeals, and suggestions. PSAs in internet media use pictures and writing, both together as a means of communication, but what can "talk" a lot is language. Language in PSAs, hereinafter referred to as text, is studied in this study with a qualitative descriptive approach and with research methods: data collection (download and copy techniques), data analysis (text structure analysis (discourse) techniques), language structure analysis techniques/grammar, and analytical techniques pragmatics). The results obtained indicate that there are three forms of ILM text, namely only images, a mixture of images and writings, and only text; 2) PSA text composition consists of themes, supports, and illustrations; 3) the language in ILM uses a mixture of foreign vocabulary, and verbs with -kan, -i, and klitika -lah. the peculiarity of the message in the PSA text is in the form of a commanding message, either directly or indirectly.Iklan layanan masyarakat (ILM) sebagai sarana komunikasi memberikan “perintah” pada masyarakat dan wujud perintah itu berupa suruhan, larangan, imbauan, dan saran. ILM dalam media internet menggunakan sarana gambar dan tulisan, keduanya bersama sebagai sarana komunikasi, tetapi yang dapat “berbicara” banyak ialah sarana bahasa. Bahasa dalam ILM, selanjutnya disebut teks dikaji dalam penelitian ini dengan pendekatan deskriptif kualitatif dan dengan metode penelitian: penjaringan data (teknik unduh dan salin), penganalisisan data (teknik analisis struktur teks (wacana), teknik analisis sturktur bahasa/gramatika, dan teknik analisis pragmatik). Hasil yang diperoleh menunjukkan bahwa 1) bentuk teks ILM ada tiga, yaitu hanya gambar, campuran gambar dan tulisan, dan hanya tulisan; 2) komposisi teks ILM terdiri atas tema, pendukung, dan ilustrasi; 3) bahasa pada ILM memanfaatkan campuran kosakata asing, dan verba berafiks –kan, -i, dan klitika –lah, 4) kekhasan kosakata pada teks ILM ialah menggunakan kata “imperatif” (jangan, ayo, mari, dsb.); dan 5) kekhasan pesan pada teks ILM ialah berupa pesan memerintah, baik secara langsung maupun taklangsung.
WACANA PESAN SINGKAT IKLAN PENAWARAN PINJAMAN
Authors: Purnami Wening Handri
Published: February 2022

Advertising media is one of the means that is considered effective in delivering messages. In the era of the development of communication technology, advertisements of loan offers are widely discussed via short messages on mobile phones. This study discusses the discourse of short message advertisements for loan offers. The purpose of this research is to describe the parts of discourse, language use, and speech acts in short message advertisements for loan offers. The study is descriptive qualitative. The data collection was carried out by recording and documenting short messages of loan offer advertisements in January-December 2020. The theories applied in this study are discourse, language use, and aspects of speech acts. In this study, three findings are presented, namely parts of discourse, language use, and speech acts. Firstly, the parts of short message advertisements for loan offers are the beginning, the content, and the end. Secondly, the findings of the language use indicate that the spelling of the short message adverts containing loan offers emphasizes the use of capital letters and abbreviations. Thirdly, speech acts in short messages in loan offer advertisements include expressive, directive, and commissive speech acts.Media iklan merupakan salah satu sarana yang dipandang efektif dalam penyampaian pesan.  Di era perkembangan teknologi komunikasi, memarak diperbincangkan iklan penawaran pinjaman melalui pesan singkat (sms) pada telepon genggam. Penelitian ini membahas wacana pesan singkat iklan penawaran pinjaman. Tujuan penelitian adalah memerikan bagian-bagian wacana, pemakaian bahasa, dan tindak tutur pada pesan singkat iklan penawaran pinjaman. Kajian bersifat kualitatif deskriptif. Pengumpulan data dilakukan dengan cara mencatat dan mendokumentasikan pesan singkat iklan penawaran pinjaman pada Januari—Desember 2020. Teori yang digunakan dalam penelitian ini ialah wacana, penggunaan bahasa, dan aspek tindak tutur. Dalam penelitian ini dipaparkan tiga temuan, yaitu bagian-bagian wacana, penggunaan bahasa, dan tindak tutur. Pertama, bagian-bagian wacana pesan singkat iklan penawaran pinjaman, yaitu awal, isi, dan akhir. Kedua, temuan penggunaan bahasa menunjukkan ejaan pada pesan singkat iklan penawaran pinjaman menekankan pada penggunaan huruf kapital dan singkatan. Ketiga, tindak tutur pada pesan singkat iklan penawaran pinjaman, mencakup tindak tutur ekspresif, direktif, dan komisif.
Adjacent Joint Restriction Differentially Influences Intra- and Inter-rater Reliability and Agreement of Goniometric Measurements
Authors: Pinto Brendan L. , Stankovic Tatjana , Frost David M. , Beach Tyson A. C.
Published: February 2022

Background

Reliability and agreement of goniometric measurements can be altered by variations in measurement technique such as restricting adjacent joints to influence bi-articular muscles. It is unknown if the influence of adjacent joint restriction is consistent across different range of motion (ROM) tests, as this has yet to be assessed within a single study. Additionally, between-study comparisons are challenged by differences between methodology, participants and raters, obscuring the development of a conceptual understanding of the extent to which adjacent joint restriction can influence goniometric ROM measurements.

Purpose

To quantify intra- and inter-rater reliability and levels of agreement of goniometric measurements across five ROM tests, with and without adjacent joint restriction.

Study Design

Descriptive reliability study

Methods

Three trained and experienced raters made two measurements of bilateral ankle dorsiflexion, first metatarsophalangeal dorsiflexion, hip extension, hip flexion, and shoulder flexion, with and without adjacent joint restriction. Intraclass correlation coefficient (ICC), standard error of measurement (SEM), along with participant, measurement/rater and random error variance were estimated.

Results

Eleven females (age 21.4 ±2.3 years) and 19 males (age 22.1 ±2.8 years) participated. Adjacent joint restriction did not influence the reliability and agreement in a consistent way across the five ROM tests. Changes in the inter-rater reliability and agreement were more pronounced compared to the intra-rater reliability and agreement. Assessing variance components (participant, measurement/rater and random error variance) that are used to calculate the ICC and SEM, improved interpretation of ICC and SEM scores.

Conclusion

The effects of adjacent joint restriction on reliability and agreement of goniometric measurements depend on the ROM test and should be considered when comparing measurements between multiple raters. Reporting variance components that are used to calculate the ICC and SEM can improve interpretation and may improve between-study comparisons, towards developing a conceptual framework to guide goniometric measurement technique.

Level of Evidence

3b
Comparison of Concurrent and Same-Day Balance Measurement Approaches in a Large Sample of Uninjured Collegiate Athletes
Authors: Saalfield Jessica , Piersol Kelsey L. , Monaco Robert , Womack Jason , Weismiller Scott A , Esopenko Carrie , Todaro Sabrina M , Conway Fiona N , Brostrand Kyle , Buckman Jennifer F.
Published: February 2022

Background

Measures of postural stability are useful in assisting the diagnosing and managing of athlete concussion. Error counting using the Balance Error Scoring System (BESS) is the clinical standard, but has notable limitations. New technologies offer the potential to increase precision and optimize testing protocols; however, whether these devices enhance clinical assessment remains unclear.

Purpose

To examine the relationships between metrics of balance performance using different measurement systems in uninjured, healthy collegiate athletes.

Study Design

Cross-sectional.

Methods

Five hundred and thirty uninjured collegiate athletes were tested using the C3Logix app, which computes ellipsoid volume as a measure of postural stability during the six standard BESS conditions, while concurrently, errors were manually counted during each condition per standard BESS protocols. The association between concurrently measured ellipsoid volumes and error counts were examined with Spearman’s correlations. From this sample, 177 participants also performed two double-leg conditions on the Biodex BioSway force plate system on the same day. This system computes Sway Index as a measure of postural stability. The association of ellipsoid volume (C3Logix) and Sway Index (Biodex) was examined with Spearman’s correlations. Individual-level data were plotted to visually depict the relationships.

Results

C3Logix ellipsoid volume and concurrently recorded error counts were significantly correlated in five of the six BESS conditions (rs:.22-.62; p< 0.0001). C3Logix ellipsoid volume and Biodex Sway Index were significantly correlated in both conditions (rs=.22-.27, p< 0.004). However, substantial variability was shown in postural stability across all three measurement approaches.

Conclusion

Modest correlation coefficients between simultaneous and same-day balance assessments in uninjured collegiate athletes suggest a need to further optimize clinical protocols for concussion diagnosis.

Level of Evidence

2b
Effectiveness of a Shoulder Exercise Program in Division I Collegiate Baseball Players During the Fall Season
Authors: Plummer Hillary A. , Plosser Shannon M. , Diaz Paul R. , Lobb Nicholas J. , Michener Lori A.
Published: February 2022

Background

Deficits in shoulder range of motion (ROM) and strength are associated with risk of arm injury in baseball players.

Purpose

The purpose of this study was to assess the effectiveness of a standardized exercise program, during the fall season, on shoulder ROM and rotational strength in collegiate baseball players.

Study Design

Prospective cohort study

Methods

Passive shoulder internal rotation (IR), external rotation (ER), and horizontal adduction ROM were measured with an inclinometer. Shoulder IR and ER strength was assessed using a hand-held dynamometer and normalized to body weight. Players performed a program of shoulder stretching and strengthening exercises, three times/week for one month and then one time/week for two months. Paired sample t-tests compared pre-intervention to post-intervention outcome measures.

Results

Division I baseball players (n=43; 19.6±1.2years, 185.8±5.5cm, 90.5±7.0kg) volunteered. From pre- to post-intervention, there were increases in horizontal adduction ROM in the throwing (Mean Difference (MD)=6.1°, 95%CI=3.7,8.5; p<0.001) and non-throwing arm (MD=8.0°, 95%CI=5.6,10.3; p<0.001), and a decrease in non-throwing arm ER ROM (MD=2.8°, 95%CI= 0.2,5.5; p=0.039). The ER ROM surplus (throwing – non-throwing) increased (MD=5.6°, 95%CI= 1.1,10.2; p=0.016). Throwing arm (MD=1.3%BW, 95%CI=0.5-2.1, p=0.003) and non-throwing arm (MD=1.2%BW, 95%CI=0.4,2.0; p=0.004) ER strength decreased. A notable, but non-significant increase in IR strength on the throwing arm (MD=1.6%BW, 95%CI=0.1,3.0; p=0.055) and decrease on the non-throwing arm (MD=1.2%BW, 95%CI=0.0,2.4; p=0.055) occurred. Additionally, throwing arm ER:IR strength ratio (MD=0.16, 95%CI=0.08,0.25; p<0.001) also decreased.

Conclusion

Changes in shoulder horizontal adduction ROM, IR strength and relative ER surplus on the throwing arm were noted at the end of the season. The lack of change in IR and ER ROM and may be related to the lack of deficits at the start of the fall season.

Level of Evidence

2.
Considerations for the Medical Management of the Circus Performance Artist and Acrobat
Authors: Faltus John , Richard Veronique
Published: February 2022

Medical management of the circus performer encompasses a wide variety of multicultural, transdisciplinary and multifaceted decision-making considerations. There is a paucity of research evidence investigating both the unique diversity of skill sets and cultural considerations in addition to injury patterns of performers within the circus environment. Since a previously established framework for supporting the health and well-being of the circus performer across various aspects of medical management does not exist in the literature, most recommendations in this regard must come from practical experience working with this highly specialized performance athlete population. The purpose of this clinical commentary is to provide the reader with a greater understanding of the unique challenges associated with the medical management of performance artists and acrobats as well as recommendations for developing an integrated approach for mitigating injury risk within a highly specialized, diverse athlete population.

Level of Evidence

5
Makna Simbolik Ritual Mabbaca-Baca di Kelurahan Ujung Tanah Kecamatan Cenrana Kabupaten Bone
Authors: Fajrin Syarifah Nur , Oruh Shermina , Agustang Andi
Published: January 2022

Penelitian ini bertujuan untuk mengetahui makna simbolik ritual mabbaca-baca dan untuk menganalisis pelaksanaan Mabbaca-bacadi Kelurahan Ujung Tanah, Kecamatan Cenrana Kabupaten Bone Penelitian ini merupakan penelitian fenomenologi dengan menggunakan 4 informan dengan metode pengumpulan data menggunakan metode Observasi, Wawancara dan Dokumentasi serta analisis deskriptif kualitatif.Hasil penelitian menunjukan bahwa makna mabaca-baca adalah amanah yang di wariskan kepada penerusnya kemudian arti ma baca dari segi yang paling utama digunakan adalah alat yang digunakan sebagai penyajian kemudian dari segi bahan yang digunakan saat pelaksanaan yang paling umum di sana memohon perlindungan dan permintaan maaf atas kesalahan yang dilakukan agar kedepanya dapat menjalankan kehidupan dengan tenag dan proesesi ritual mabaca- baca adalah yang dilakukan semua orang yang ada dilnkungan tersebut dan keluarga yang akan datang untuk mempersiapkan segala sesuatu yang dibutuhkan,para masyarakat dalam proses mabca baca membagi agar saling mempercayai dalam melaksanakan tugas-tugas tersebut dan bacaan di atas sudah memang ada yang disiapkan secara khusus saat melakukan ritual apapun itu semuanya dan secara otomatis persiapan pun dalam melakukan proses mabaca juga yang bertujuan agara doa yang bertujuan utarakan dapat dikabulkan.
The Use of a Convolutional Neural Network in Detecting Soldering Faults from a Printed Circuit Board Assembly
Authors: Akhtar Muhammad Bilal
Published: February 2022

Automatic Optical Inspection (AOI) is any method of detecting defects during a Printed Circuit Board (PCB) manufacturing process. Early AOI methods were based on classic image processing algorithms using a reference PCB. The traditional methods require very complex and inflexible preprocessing stages. With recent advances in the field of deep learning, especially Convolutional Neural Networks (CNN), automating various computer vision tasks has been established. Limited research has been carried out in the past on using CNN for AOI. The present systems are inflexible and require a lot of preprocessing steps or a complex illumination system to improve the accuracy. This paper studies the effectiveness of using CNN to detect soldering bridge faults in a PCB assembly. The paper presents a method for designing an optimized CNN architecture to detect soldering faults in a PCBA. The proposed CNN architecture is compared with the state-of-the-art object detection architecture, namely YOLO, with respect to detection accuracy, processing time, and memory requirement. The results of our experiments show that the proposed CNN architecture has a 3.0% better average precision, has 50% less number of parameters and infers in half the time as YOLO. The experimental results prove the effectiveness of using CNN in AOI by using images of a PCB assembly without any reference image, any complex preprocessing stage, or a complex illumination system. Doi: 10.28991/HIJ-2022-03-01-01 Full Text: PDF
Susheel Kumar Sharma’s Unwinding Self (Poetry)
Authors: Balachandran Dr. K.
Published: February 2022

Susheel Kumar Sharma’s Unwinding Self (Poetry), Cuttack:Vishvanatha Kaviraj Institute, 2020, Pages 152, Price: Rs.250.
Concept and model of regional economic management based on strategic planning tools
Authors: Domenko Yuriy
Published: February 2022

Today, strategic planning plays an important role not only in the system of general management, but also in state and municipal management. Strategic planning is implemented in particular in the development and implementation of strategic documents. The main strategic documents include the strategy of socio-economic development (federation, region, municipality). Despite the fact that the strategy should be a dynamic document that allows, and sometimes requires changes, we note the need to define its clear conceptual foundations, including a set of effective strategic planning tools.
ENTROPY AS A MEASURE OF CREATIVITY IN THE ECONOMY AND SPIRITUAL FREEDOM OF SOCIETY
Authors: Afonin Petr , Ostanin Vladimir
Published: February 2022

The article is devoted to the analysis of trends in the expansion of the apparatus for assessing the development of the economy and the spiritual freedom of society using analogs of mathematical dependences describing entropy in dynamic systems in which, as well as in economic and social systems, there is a process of energy exchange. The constructed verbal model made it possible to assess the possibilities and applicability of thermodynamic dependencies for describing processes in the economy.
THEORETICAL ASPECTS OF THE STAFF TRAINING SYSTEM: FOREIGN EXPERIENCE
Authors: Galstyan Vladislav , Erokhin Sergey , Gorbachevskaya Anastasia
Published: February 2022

Today, society pays great attention to the development and reproduction of the human personality, career guidance, professional development, personnel training at the enterprise acquires a special role, and if we are talking about a hospitality industry enterprise, this aspect is especially significant, because for the effective operation of a hotel enterprise, a specialist should know everything about the service sector of your hotel, know the culture and etiquette.
Structuring of the accounting and control function of managing material costs for conducting experimental work by an industrial enterprise
Authors: Igor' Efimovich
Published: February 2022

The article is devoted to the problems of economic and organizational perfection of the process of consumption of material resources in the course of experimental work carried out by an economic entity of the real sector of the economy. The conducted studies of the adopted model of management of this process have shown the need to restructure the functions of accounting and control of the resources in question in terms of their significant strengthening; the need for balanced integration in a single information and instrumental space, which determined the purpose of the study, the key objectives of which were the development and implementation of the synergy of order-based cost accounting, differentiated in the context of each work and on-farm control carried out by the "Standard cost" method; justification of the choice of the method of rationing material resources, adequate to the specifics of experimental work and the development of separate forms of output information. The obtained results allowed to significantly improve the resource management system of industrial enterprises, create conditions for the successful implementation of resource-saving programs, the formation of an optimal information and instrumental space for the management of experimental work, which are one of the main tools of technological development, competitive advantages and business profitability.
State-Church relations in ensuring non-tariff regulation of cross-border movement of cultural treasures
Authors: Afonin Petr
Published: February 2022

The development of customs control of cultural values that make up the historical and spiritual memory of Russia is an integral task of the relationship between the Federal Customs Service of Russia and the Russian Orthodox Church. The paper considers the key elements of modern interaction between two dominant institutional structures of modern Russia – the federal executive authority in the field of customs affairs, ensuring the performance of fiscal and law enforcement functions in ensuring the economic security of the state and the Russian Orthodox Church - the spiritual and moral center for ensuring the integrity of the Russian state throughout its more than 1000-year history.
MODERN THREATS TO THE DEVELOPMENT OF THE FISHERIES COMPLEX AND THEIR IMPACT ON ENSURING FOOD SECURITY OF THE RUSSIAN FEDERATION
Authors: Rodionov Aleksey
Published: February 2022

The article presents the results of the analysis of modern threats to the development of the fisheries complex and their impact on ensuring food security of the Russian Federation. The role of export-import operations in the formation of the balance of consumption of finished fish and seafood products is determined. The threats of further aggravation of relations with key consumers of Russian frozen fish exports are outlined.
EVOLUTION OF E-MARKETING TOOLS
Authors: Maksaev Artur , Vakulenko Vladimir
Published: February 2022

Email marketing tools now enable companies to dramatically improve customer engagement and balance their marketing budgets. To identify trends and tendencies, it is advisable to investigate the evolutionary features of electronic marketing tools, assess their classification specificity, study the functional features and analyze the transformational vectors of electronic marketing.

Marketing in effectively functioning and constantly developing companies is designed in such a way that, penetrating into the management complex of implementing strategies and innovations, it instantly reacts to the emergence of the latest electronic tools and technological solutions, forms its own ways of preventing an unstable external environment.
BIOECONOMICS AS A NEW PARADIGM OF DEVELOPMENT
Authors: Nesterenko Marina , Komlatsky Grigory
Published: February 2022

The article reveals the role and importance of bioeconomics in the context of the transition from a linear economic model to a circular closed cycle based on the "cascade consumption" of renewable biological resources. It is determined that the main task of the domestic economy at the present stage should involve moving away from the raw material model, where the production, availability and use of biomass can be the key conditions. The official classification of biotechnologies in the Russian Federation is given, organizational aspects of supporting their development are disclosed, where an important milestone in the greening of the domestic economy is the approval by the government of the Strategy of Socio-Economic Development of the Russian Federation until 2050 with a low level of greenhouse gas emissions. However, it is noted that within the framework of organizational and economic regulation, a fragmentary approach dominates in revealing the essence of bioeconomics, where the development of biotechnologies is possible in the separate accounting of income from their use in each individual production sector, i.e. a "linear" concept is declared to a greater extent. In accordance with this, the tools of the system of organizational measures for the translation of the transition from linear economics to circular bioeconomics are proposed.
Kematangan Karier Siswa: Peranan Tipe Kepribadian dan Dukungan Sosial
Authors: Milah Mida Tahmidiyatul , Sudirman Deden , Fridayanti
Published: February 2022

Kematangan karier merupakan kesiapan individu dalam menentukan karier yang tepat di masa mendatang sesuai dengan pengetahuan yang diperlukan untuk membuat pilihan karier yang realistis. Penelitian ini dilakukan dengan tujuan untuk mengetahui peranan atau pengaruh faktor kepribadian dan dukungan sosial terhadap kematangan karier siswa. Metode penelitian yang digunakan adalah pendekatan kuantitatif dengan analisis kausalitas. Responden penelitian ini sebanyak 205 partisipan (perempuan 164 orang dan laki-laki 41orang; dengan rentang usia 17-19 tahun mean = 17 sd = 0.54). Teknik pengumpulan data menggunakan kuesioner big five personality (BFI, Pervin, & John, 1999), dukungan sosial (social provisions scale, Cutrona, C. E., Russell, D. W. 1987), dan kematangan karier (CMI-Form C, Savickas 2011). Analisis data dalam penelitian ini menggunakan analisis regresi linier berganda.  Hasil penelitian menunjukan bahwa dukungan sosial berkontribusi secara signifikan terhadap kematangan karir baik secara simultan atau terpisah. Adapun dalam hal factor kepribadian, meski secara Bersama-sama factor kepribadian dan dukungan sosial berpengaruh terhadap kematangan karir, namun bila ditelisik lebih jauh diperoleh hasil bahwa faktor kepribadian concientiounesslah  yang memiliki peran signifikan terhadap kematangan karir, Adapun faktor-faktor kepribadian lainnya tidak berpengaruh secara signifikan.
Las TIC en el contexto familiar en tiempos de confinamiento: experiencias de conectividad y comunicación de estudiantes universitarios
Authors: Silva-Castillo Jorge , Peñafiel-Rodríguez Mirian , Cazorla-Basantes Amparo
Published: February 2022

Frente a la situación de emergencia sanitaria ocurrida desde el año 2020 por la pandemia mundial de coronavirus covid-19, la sociedad tuvo que irse adaptando a nuevos contextos de la mano de las Tecnologías de la Información y la Comunicación (TIC).   El trabajo presencial se vio interrumpido en sus actividades cotidianas por el confinamiento obligatorio y a la par de aquello se optó por la modalidad virtual que durante varios años atrás ya se aplicaba en la educación superior a distancia y en ámbitos de la economía digital, pero ahora se vio fortalecida por la necesidad de seguir cumpliendo la misma labor específicamente en el campo educativo.  La utilización de las TIC se ha convertido en un elemento imprescindible, y bajo esa necesidad confluyeron los actores sociales con distintas realidades, por lo cual el presente estudio tuvo como objetivo revelar cuales fueron las formas de acceso a la información y la comunicación por parte de los estudiantes de la Universidad Nacional de Chimborazo (UNACH) durante el año 2020. Se realizó un diagnóstico cuantitativo del porcentaje de conectividad, tipo de servicio, con un diseño no experimental transeccional descriptivo en referencia al acceso a dispositivos tecnológicos que tienen los estudiantes universitarios. Los resultados obtenidos en esta investigación permitieron conocer que un 70% de estudiantes de las cuatro facultades que conforman la UNACH durante el año 2020 hicieron uso compartido de dispositivos con otros miembros de la familia para ejecutar sus actividades académicas y de teletrabajo dentro del hogar.