bluuebunny/crossref_metadata_2025 huggingface dataset:
Contemporaneidad, imagen violenta y estetización en Centroamérica
Authors: Rosa Gabriel Galeano
Published: January 2022

El artículo explica la configuración histórica del arte contemporáneo en Centroamérica a partir de los cambios y transformaciones institucionales emanadas en la última década del siglo XX. Señala las diferencias de la producción de la generación de los noventa con relación a las prácticas artísticas gestionadas durante la década de los ochenta y, posteriormente, se señala el desplazamiento de la tradición eminentemente pictórica a campos más próximos a la creación participativa en medio urbano.Se reflexiona sobre la influencia de la violencia en la conformación de los imaginarios simbólicos y se alerta sobre el peligro de la excesiva proliferación de la imagen violenta en las representaciones artísticas, ante todo, si su abordaje se realiza como parte de una agenda que contribuye al espectáculo y a la excitación de la percepción mediante la representación directa de la violencia que despolitiza la imagen y fomenta muy poco la comprensión crítica del mundo.
DECONSTRUCTION DE LA PERCEPTION – VOIR ET ECRIRE DANS LA PHILOSOPHIE DE DESCARTES
Authors: Vinolo Stéphane
Published: January 2022

La théorie de la perception emprunte, chez Descartes, deux chemins différents. D’un côté, la perception interne se développe selon le paradigme visuel de l’intuitus ; de l’autre, la perception externe est pensée à l’aune d’un modèle discursif. À la présentation s’opposerait donc une signification. Or, contre les commentateurs qui ont fait de Descartes le philosophe ayant ouvert l’ère de la représentation, l’auteur montre que le modèle discursif prime sur le paradigme visuel et que bien que Descartes affirme que les idées sont comme des images et des tableaux, son modèle de la perception est en fait celui de la fable, c’est-à-dire d’un texte.
"El don de dar vida": Análisis de la producción de la mujer como persona en culturas híbridas
Authors: Contreras Tinoco Karla Alejandra , Castañeda Rentería Liliana Ibeth
Published: January 2022

En este ensayo respondemos a la pregunta: ¿Qué posibilidades, obstáculos y tensiones ofrece “el don de dar vida” a la producción de la mujer como persona en México?, para ello analizamos una expresión común y de uso popular en México: “el don de dar vida”. Identificamos que la expresión tiene similitudes, aunque también diferencias con “el don” del que habló Marcel Mauss. Una de las diferencias es que actualmente la expresión “el don de dar vida” se usa en las culturas híbridas. Mientras el don del que habla Mauss es propio de sociedades colectivistas. En las conclusiones presentamos el porqué de estas diferencias, y los efectos que generan para la producción del sujeto mujer.
Miguel Covarrubias (1904-1955) y la configuración de la estética olmeca
Authors: Ríos Sánchez Miguel Ángel
Published: January 2022

Hace tan solo unos ciento sesenta años que la denominada cultura olmeca salió a la luz. En la historia de la definición de su estilo artístico ocupa un lugar destacado el artista mexicano Miguel Covarrubias. En el artículo realizamos un análisis pormenorizado de su obra, intentando mostrar la evolución de sus ideas artísticas y la importancia que tuvieron a la hora de configurar lo que hoy se denomina «estética olmeca». Se analizan sus presupuestos teóricos y la enorme influencia que sus tesis tienen, aun hoy, a la hora de analizar la que muchos consideran la «cultura madre» de Mesoamérica.
Tientos nietzscheanos o el duende en la filosofía
Authors: Hoyos Sánchez Inmaculada
Published: January 2022

El propósito de este estudio es reflexionar acerca de las aportaciones de la obra de M. Barrios Casares en el nuevo contexto hermenéutico en el que se encuentran los estudios nietzscheanos actualmente. El hilo conductor del estudio se articula en torno a la última publicación del filósofo sevillano, Tentativas sobre Nietzsche (2019), cuyas líneas fundamentales son analizadas aquí. El segundo de los objetivos del presente trabajo reside en señalar algunos vínculos entre esta última publicación de M. Barrios y su trabajo realizado anteriormente en el campo de la traducción, la edición y el ensayo.
Research Commentary: Bridging the Gaps in Perspectives on Equity in Mathematics Education
Authors: Lubienski Sarah Theule , Gutiérrez Rochelle
Published: January 2022

In this rejoinder, the authors further detail their positions on the role of gaps analyses in mathematics education research as outlined in the previous 2 articles. They clarify areas of agreement and probe areas of disagreement, focusing on the benefits and dangers they see in either emphasizing educational disparities between groups or shifting the focus to the advancement of particular groups. The authors discuss ways in which their backgrounds have shaped their differences in perspectives and priorities, including whether socioeconomic disparities or racial and ethnic identity are more focal in their work. Suggestions for lessening the dangers of gaps analyses are discussed.
The relationship between the perception of reduced performance due to injury or illness and basic psychological need satisfaction in Norwegian youth elite handball: a cross-lagged panel analysis
Authors: Gjesdal Siv , Bjørndal Christian Thue , Luteberget Live Steinnes
Published: January 2022

This study investigated the relationship between perceived reduction in performance due to injury or illness (RPII) and basic psychological need satisfaction in youth elite handball. Participants were 174 elite youth handball players between 15 to 18 years of age, from five different sport schools. It was a quantitative study, with two time points (one week apart), resulting in a crossed-lagged structural equation model. Competence and relatedness satisfaction were found invariant across the two time points, autonomy was not. The structural model showed good fit ((S- B χ²) = [df = 130, N= 174] = 182.327, p < .0017; CFI = .96; RMSEA = .05 [.03-.06], and SRMR = .08). Competence (β= .64, 95%CI: .51, .76), relatedness (β= .77, 95%CI: .66, .88) and RPII (β= .51, 95%CI: .37, .66) showed moderate temporal stability. When accounting for previous levels of the basic psychological needs, RPII negatively predicted competence (β= -.20, 95%CI: -.35, .83) and relatedness (β= -.16, 95%CI: -.30, -.01). Taken together, these findings suggest that experiencing RPII can have implications for basic psychological need satisfaction in youth elite handball, showing that factors other than psychosocial ones may play a role therein.
Danske seniorers (65+) motiver og barrierer for fysisk aktivitet
Authors: Larsen Merete Lundby , Ryom Knud
Published: January 2022

The proportion of older adults is increasing in Denmark. At the same time physical activity is becoming an increasingly popular arena to prevent illness, promote health and increase life quality. This case study examined older adults’ (65-75 y) motives and barriers for participation in organised physical activity. Using a single embedded case study, we collected data through semi structured interviews and observation. The theoretical framework is Ryan & Deci’s Self-Determination Theory (SDT). Results of this study indicate that informants had several intrinsic and extrinsic motives. Among the extrinsic motives were better health, absence of illness, a good retirement and complying with social norms. A number of integrated and structural motives also exist: positive experience with sports, appropriate challenges, social interaction, diverse sports activities and freedom of choice. The older adults described barriers such as: difficult to self-initiate participation in sports, health related issues and lacking experiences with sports. Furthermore, the study discusses behaviour change triggers to stimulate healthy behaviour in old age using a revised FBM-model. In addition, organised physical activity that promotes satisfaction of the psychological needs is essential for the adherence. Based on the results and discussion, implications for practice are provided through recommendations on physical activity for older adults, based on organisation, activities and recruitment.
Results of this study indicate that informants had several intrinsic and extrinsic motives. Among the extrinsic motives were better health, absence of illness, a good retirement and complying with social norms. A number of integrated and structural motives also exist positive experience with sports, appropriate challenges, social interaction, diverse sports activities and freedom of choice. The older adults described barriers such as: difficult to self-initiate participation in sports, health related issues and lacking experiences with sports.
Furthermore, the study discusses behaviour change triggers to stimulate healthy behaviour in old age using a revised FBM-model. In addition, organised physical activity that promotes satisfaction of the psychological needs is essential for the adherence. Based on the results and discussion, implications for practice are provided through recommendations on physical activity for older adults, based on organisation, activities and recruitment.
La «trilogía» de Bill Douglas (My Childhood, 1972; My Ain Folk, 1973; My Way Home, 1978)
Authors: Zunzunegui Santos
Published: January 2022

Pieza fundamental del cine británico de la década de los años setenta del pasado siglo y durante mucho tiempo poco apreciada en su país, la trilogía de Bill Douglas convierte la durísima infancia y adolescencia de su autor en imágenes imperecederas mediante un ejercicio en el que, siguiendo la estela de Chejov, la memoria es filtrada a través de un cedazo para que solo permanezca lo esencial en el recuerdo. Tres pequeños grandes filmes que nos hacen transitar a través de una sensibilidad a flor de piel que se expresa en un arte alquímico de la imagen en el que se coagula una terrible experiencia familiar y social transmutándola con intensidad, simplicidad y violencia.
Babel Revisitada
Authors: Gómez Cadenas Juan José , Guagnelli Marco
Published: January 2022

En 1997, Iván Almeida, catedrático del Borges Center en Aarhus, escribe a Umberto Eco, haciéndole notar un aparente error en un reciente artículo suyo. Eco, copiando verbatim la traducción del emintente Lucentini,  asevera que las galerías de la famosa Biblioteca de Babel, constan de «veinticinco estantes, a razón de cinco por lado, que cubren todos los lados menos uno», mientras que en la versión original, Borges asegura que «veinte estantes, a razón de cinco por lado, cubren todos los lados menos dos». Y eso no es todo. En la traducción de Lucentini se lee que cada uno de los volúmenes de la Biblioteca consta de cuarenta líneas y cada línea de cuarenta letras. Para Borges, sin embargo, el número de letras por línea es de ochenta. En este artículo se demuestra que dichos errores, aparentemente banales, encierran una revelación trascendente —quizás terrible— sobre el Universo.
Dar nombre a lo ignoto. Idilio y tragedia en Hölderlin (con una coda celaniana)
Authors: Ferrer Anacleto
Published: January 2022

El 4 de junio de 1799, en carta a Neuffer, Hölderlin cita por vez primera el nombre de una obra que dice tener «acabada exceptuando el último acto». Se llamará «La muerte de Empédocles». Se propone publicarla en los primeros números de una revista poética mensual «para damas» que tiene la intención de dirigir si consigue interesar en el proyecto al editor Johann Friedrich Steinkopf. Se llamará Iduna. De los trabajos asociados al plan de Iduna solo pervivirán fragmentos y el texto acabado que Steinkopf le encargara sobre Emilia. La redacción de Empédocles y Emilia coinciden en el tiempo, de un lado una tragedia poetológicamente fundamentada, del otro un idilio sentimental solo aparentemente de circunstancias. A través de uno y otro texto, desarrollados en una época de inestabilidad política acusada, el poeta responde (o al menos lo intenta) a su propio interrogante: ¿Para qué poetas en tiempo menesteroso? Es ésta una cuestión a la que también se enfrentará siglo y medio después Paul Celan.
La presencia del cómic en el 45 Salón Nacional de Artistas de Colombia
Authors: Conde Aldana Juan Alberto , Gil Guzmán Diana Paola
Published: January 2022

La incorporación del cómic en exhibiciones artísticas es un campo en expansión. En Colombia, un reciente caso de adaptación museística de la historieta aconteció en el 45 Salón Nacional de Artistas, El revés de la trama, que abrió algunos espacios expositivos al cómic en las curadurías Arquitecturas narrativas, Llamitas al viento y Contrainformación. En este artículo proponemos una aproximación a estas tres exposiciones, según las conceptualizaciones del cómic y el espacio de exhibición que cada una de ellas ofrece: en Arquitecturas narrativas, el paralelo entre la gestión del espacio en el bidimensional de la página y el tridimensional de la exposición. En Llamitas al viento, la inclusión del cómic en el ámbito de las publicaciones artísticas y la alternancia entre curaduría de textos y diseño de exposición. Y en Contrainformación, la resignificación de cómics que provienen del auge de los movimientos sociales y campesinos de la década de los setenta y de una historieta comisionada para la exhibición.
Santos Zunzunegui, Imagen sobre imagen. Mis Historias del Cine I
Authors: Zumalde Imanol
Published: January 2022

Santos Zunzunegui, Imagen sobre imagen. Mis Historias del Cine I, Valencia: Shangrila, 2021, 214 págs.
Científicas y científicos, ¡no bajéis del escenario!
Authors:   Universitat Oberta de Catalunya, López-Borrull Alexandre
Published: January 2022

Más allá de las opiniones favorables o no a los Juegos Olímpicos de Barcelona 92, una de las imágenes icónicas es, sin duda, el caos generado durante la ceremonia de clausura, mientras cantaban los Manolos y una multitud de atletas subía al escenario. En aquel desorden, destacó la voz del recordado Constantino Romero pidiéndoles que bajaran del escenario. Parafraseo aquel llamamiento para hacer el mío a científicas y científicos: ¡Por favor, no dejéis las redes sociales! En este artículo explicaremos el valor del trabajo que hacen, por qué es necesario que estén en estas y por qué se pide no abandonarlas, así como el modo de lograrlo.
¿Quién es el último?
Authors:   Universitat Oberta de Catalunya, Rosales Andrea
Published: January 2022

«La pandemia nos hará mejores», decían lemas y artículos de prensa, cuando la COVID-19 irrumpió con toda su letalidad en nuestra sociedad, a finales del invierno de 2020. «Con la llegada del virus, tendremos que ser otros», decía la gente en la calle, y destacaban los expertos. «Tenemos que transformarnos», replicaban asociaciones de vecinos y grupos civiles.
Accumulation of moisture of cellular concrete wall structures in the annual cycle
Authors: Shakirova Veronika Aleksandrovna
Published: January 2022

This article delivers the calculation of moisture accumulation of the wall structure in the annual cycle for the climatic conditions of Krasnoyarsk. Analysis is conducted on the multilayer wall structure made of cellular concrete, with the plaster based on cement-sand mortar as top layer and use of thermal insulation in the form of mineral wool board. The subject of this research is the typical corner unit made of cellular concrete in combination with monolithic belt and an inter-floor overlap used in low-rise construction. The author acquires the results of moisture accumulation in layers of the structure for each month within one year, depending on the climatic parameters. The novelty lies in the fact that the outdoor climate and sorption moisture influences the accumulation of moisture in construction materials, creating a large seasonal increase in moisture. Consideration of these factors in the design process, allows making the structures more durable and energy-efficient. The conclusion is made that the distribution of moisture structural layers under climatic conditions. Krasnoyarsk is uneven throughout the year; however, meet the regulations. It is recommended to conducted regulation in the design in order to maintain the level of moisture in construction materials
To the question of corporeal experience in Bernard Tschumi’s theory of architecture
Authors: Petrushikhina Svetlana Vladimirovna
Published: January 2022

The subject of this research is the theoretical works of Bernard Tschumi. The goal is to determine the place of the problem of corporeal experience in the theory of architecture of developed by the Swiss architect. For achieving the set goal, the author examines the key themes of his works –  the question of boundaries and limits of architecture, architecture as the place of occurrence of the event; as well as a number of concepts – “pleasure”, “limits”, “violence”. The texts created by Bernard Tschumi over the period from 1977 to 1981: “The Pleasure of Architecture” (1977), the article “Violence of Architecture” (1981), and a series of essays “Architecture and Limits” (1980–1981) served as the sources for this analysis. B. Tschumi did not dedicate works to the problem of corporeal experience alone; however, addresses this problem in the context of interaction between the audience and the building. His attention is focused on the viewer’s sensory experiences emerging in direct contact with the architectural object. On the one hand, this apposes B. Tschumi with the representatives of the phenomenology of architecture – S. Hall and J. Pallasmaa; all of them emphasizes the kinesthetic, nonverbal nature of corporeal experience in the perception of structures, their internal space and materials. On the other hand, B. Tschumi describes the relations between the body and the building as violent. Violence in the relations between man and architecture is ubiquitous: it is the interference of of a person into the architectural space, as well as feeling of discomfort provoked by the architectural space.
Structural development of tourist recreational spaces in Siberia (on the example of Krasnoyarsk Krai)
Authors: Yur Yuliya Grigor'evna
Published: January 2022

The goal of this article lies in the analysis of the natural peculiarities of Krasnoyarsk Krai that comprise the tourist recreational potential of Siberia on the example of the Putorana State Natural Reserve, which is recognized by UNESCO as a World Natural Heritage Site. Research methodology employs the theoretical methods of analysis, generalization and synthesis of scientific methods with the use of data from scientific sources. The main results of the conducted research are as follows: 1) classification of tourist recreational zones by typological and taxonomic characteristics; 2) substantiation of the forms and types of tourism and recreation in the conditions of specially protected natural areas. The acquired results can be implemented in planning the efficient utilization of natural resources in Krasnoyarsk Krai and Siberian regions that have natural heritage sites. The scientific novelty and conclusions are associated with determination of natural resources of Krasnoyarsk Krai attractive for the development of tourism and recreational activities; as well as analysis and substantiation of the forms and types of tourism and recreation that are geared towards the vector of activity of natural heritage sites (specially protected natural areas) located in the region. It is noted that the measures carried out for organizing tourist recreational activity, without taking into account the peculiarities of functionality of natural heritage sites, increase the risks of anthropogenic impact and require constant monitoring and control of their implementation.
The development of normative requirements for buildings of preschool educational institutions
Authors: Mingareeva Rumiya Ruslanovna
Published: January 2022

Preschool education is intended for acquiring primary skills and knowledge. This is facilitated by the conditions in preschool educational institutions. The subject of this research is the normative requirements for preschool educational institutions. The goal lies in analysis of the development of normative requirements for preschool educational institutions. The task is to examine the basic technical regulations in the sphere of preschool education, as well as determine the changes in normative regulations. The research leans on the scientific materials on the topic and the content of the normative legal acts. The research material includes the results of scientific research on this topic and the content of regulatory legal acts. The article provides general characteristics to the development of normative requirements for pre-school buildings. The concept of “kindergarten” is introduced in the Building Code II-64-80. The normative legal acts outline the layout and architectural solutions of the buildings. Relevance of this topic is substantiated by the development of pre-school education aimed at improving accessibility and availability of place in preschool educational institutions; for this purpose the new ones will be built. The research relies on the historical development of architectural regulations, standard projects of Soviet period, sanitary and epidemiological requirements, greening of territories, modern architecture; reconstruction of preschool buildings in modern urban environment. The conducted analysis of the scientific works of the experts reveals the following peculiarities: historical development of architecture of preschool buildings in the Soviet period and emergence of new types; requirements for land allocated for this purpose; reconstruction of the existing preschool buildings. The first technical regulations set the basic requirements for project design and allocated land, standard values for indoor areas, noise and insolation levels; sanitary and epidemiological rules were established later on.
Historical development of the concept of segmentation in the housing market and emergence of approaches towards segmentation
Authors: Sondueva Sesegma Rinchinovna
Published: January 2022

The subject of this research is the development of the concept of segmentation in the housing market and emergence of approaches towards segmentation. The object of is the term “segmentation” and approaches towards this method. The author examines the historical development of this concept, as well as the criteria for segmentation of commodities. Description is given to the methods of segmentation in the marketing sphere. The author determines the methods used for segmentation of real estate objects, as well as the variants of structurization and segmentation of the real estate market. The advantages of market segmentation in comparison with the traditional method of mass marketing are outlined. The author reveals that the concept of segmentation has existed for over 70 years. There are two traditional methods of segmentation used worldwide: “post hoc” and “a priory”. Segmentation of residential market is conducted via “a priory” method. The author detects the method used for segmentation of residential objects and the criteria in studying the residential market. The need for segmentation of residential objects is substantiated by the fact that consumer requirements change over time, and segmentation allows determining the target audience and preferences of the potential customers.
Ridge-type suspended waveguide Brillouin laser
Authors: Wang Wu-Yue , Yu Yu , Li Yun-Fei , Wang Gong , Li Kai , Wang Zhi-Yong , Song Chang-Yu , Li Sen-Sen , Li Yu-Hai , Liu Tong-Yu , Yan Xiu-Sheng , Wang Yu-Lei , Lü Zhi-Wei ,   Center for Advanced Laser Technology, Hebei University of Technology, Tianjin 300401, China,   Hebei Key Laboratory of Advanced Laser Technology and Equipment, Tianjin 300401, China,   Science and Technology on Electro-Optical Information Security Control Laboratory, Tianjin 300308, China
Published: January 2022

As is well known, the on-chip waveguide with high Brillouin gain has many applications in the field of photonics. Brillouin lasers on silicon substrates are widely used in frequency tunable laser emission, mode-locked pulsed lasers, low-noise oscillators and optical gyroscopes. However, in a silicon-based Brillouin laser, a long waveguide length is still used to achieve Brillouin laser output, which is not conducive to on-chip integration. In this work is proposed a new type of waveguide structure consisting of chalcogenide As2S3 rectangles and an air slit. Owing to the existence of the air gap, the radiation pressure makes the enhancement of Brillouin nonlinearity much higher than the enhancement caused only by the material nonlinearity. This makes the Brillouin gain reach 1.78 × 105 W–1·m–1, which is nearly 10 times larger than the previously reported backward SBS gain of 2.88 × 104 W–1·m–1, resulting in phonon frequency tuning in a 4.2–7.0 GHz range. This method provides a new idea for designing nano-scaled optical waveguides for forward stimulated Brillouin scattering, and at the same time, this enhanced broadband coherent phonon emission paves the way for improving the hybrid on-chip CMOS signal processing technology.
Enhancing Cucurbita pepo Growth, Productivity, and Fruit Quality using Bacilli Strains and Cyanobacteria Treatments
Authors: Elsayed Ashmawi Ashmawi , El-Emshaty Amira M , Salem Gehan Mohamed , Ghazal Mona Fekry
Published: January 2022

Two successful field experiments were carried out during 2020and 2021 growing seasons to evaluate the effect of bio fertilizers; Bacillus amyloliquifaciens (BA), Bacillus megaterium (BM) and cyanobacteria inoculation on the vegetative growth, growth parameters and plant chemical content of Cucurbita pepo (Squash) crop. The study of mixed inoculation with both Bacillus strains, and cyanobacteria was found to improve vegetative growth, plant chemical contents and positive microbial activity in the soil Rhizosphere in comparison to un-inoculated plants. Soil available nutrients (N and K) increased significantly with BA and BM combined with cyanobacteria while available phosphorus gave most increase with BM.
Assessment of Tobacco Dependence in Al-Bayda City, Libya
Authors: Gazi Zainab , Shamata Awatif
Published: January 2022

Tobacco is the second leading cause of the death in adults in the world today. This is because of tobacco dependence. Therefore, aim of this study is to assess the level of nicotine dependence through a small random group of smokers in the city of Al-Bayda using the Fagerstrom test for nicotine dependence and to know the extent of desire to quit and take action. The study included 150 male smokers, with an age group ranging between 18-60 years, in the period between February and June 2020 through a questionnaire containing six questions from the Fagerstrom test and collected smoking risks and presence of smoking cessation medications. Data were collected and statistically evaluated using chi-square. Most of the participants had a family history, they were smoking imitating brother, father and friends. The average number of cigarettes consumed was more than 31 cigarettes per day, with a 5-minute time difference being the highest. The rate of desire to smoke was observed in the morning hours more than others. The proportion was also high for those who were unable to stop in public even while ill. Most of them are aware of the existence of drugs that help in smoking cessation. As for the attempts to quit, there were attempts during different periods of time, most of which failed due to physical and social reasons. Most of the results indicate a high rate of dependence among smokers, for reasons that may be social and economic. Therefore, we need more data and a wider study area through health centers and try to understand the reasons for returning to smoking and treating them. work to validate reliability.
Perancangan Ilustrasi sebagai Edukasi tentang Polusi Akibat Limbah Cair Produksi Fashion
Authors: Wijaya Annetta Dewi , Wicandra Obed Bima , Asthararianty Asthararianty
Published: January 2022

Meski dibutuhkan dalam kehidupan sehari-hari, fashion sebagai sebuah industri memiliki dampak yang sangat buruk pada lingkungan. Khususnya tahapan produksi fashion yaitu dyeing menghasilkan banyak sekali limbah cair yang mencemari perairan, sehingga berdampak buruk pada hewan dan tanaman, dan juga bisa menimbulkan penyakit pada manusia. Tapi masyarakat masih kurang tahu dan tidak peduli terhadap masalah ini sehingga mengonsumsi fashion tanpa dipikirkan dahulu. Perancangan ini diharapkan dapat meningkatkan kepedulian masyarakat sehingga mendorong mereka untuk mengubah kebiasaan konsumsi fashion-nya.
Perancangan Kemasan Inovatif Madu Merek “Sentra Madu” untuk Orang Dewasa
Authors: Violetta Ellen , Yuwono Elisabeth Christine , Yusuf Vanessa
Published: January 2022

Sentra Madu merupakan merek madu lokal yang berpusat di Surabaya. Sentra Madu menjual 13 jenis varian produk, akan tetapi dengan banyaknya jenis varian madu yang ditawarkan, masih banyak orang yang belum mengenal merek ini. Oleh karena itu, akan dilakukan redesain kemasan dan membuat kemasan inovatif madu yang dapat mengedukasi masyarakat mengenai jenis-jenis dan manfaat madu. Sehingga kemasan madu yang baru diharapkan dapat menarik konsumen untuk mengkonsumsi madu dan produk Sentra Madu semakin dikenal oleh konsumen.
Perancangan Media Interaktif Escape Room Sebagai Media Promosi Pandora Experience di Surabaya
Authors: Hendrawan Edwin , Banindro Baskoro Suryo , Yulianto Yusuf Hendra
Published: January 2022

Pada kenyataannya wahana escape room merupakan sebuah hiburan yang kurang diminati oleh masyarakat, sehingga perusahaan Pandora Experience mengalami kesulitan dalam menggaet calon konsumennya. Kemajuan teknologi yang semakin canggih saat ini tidak menutup kemungkinan untuk membuat sesuatu yang unik, dalam hal ini adalah media interaktif berupa aplikasi yang beranama Unravel. Unravel merupakan aplikasi yang dapat diakses melalui device Android, dan penggunanya dapat berinteraksi dalam aplikasi tersebut. Untuk itu dengan membuat perancangan media interaktif escape room dapat menarik minat dari calon konsumen Pandora Experience, untuk mencoba wahana escape room.
Perancangan Personal Branding Michael Aldi untuk Berkontribusi dalam Menghadapi College Depression pada Mahasiswa
Authors: Suyanti Yesica , Damajanti Maria Nala , Muljosumarto Cindy
Published: January 2022

College depression merupakan depresi yang dialami oleh banyak mahasiswa dikarenakan perasaan tertekan dari bertambahnya tanggung jawab serta gaya hidup yang tidak sehat. Maka dari itu mahasiswa membutuhkan sebuah sosok atau media yang dekat dan dapat menghibur mereka, yaitu musik. Musik menjadi media yang praktis dan dapat dilakukan bersamaan disaat mereka menyelesaikan tanggung jawab mereka. Michael Aldi merupakan musisi baru dan dekat dengan mahasiswa. Michael Aldi menginginkan musiknya dapat memberikan dampak positif dan membantu pendengarnya, namun musik Michael Aldi belum tersampaikan kepada target dengan tepat karena belum memiliki Brand Identity yang jelas. Lewat perancangan dengan menggunakan metode analisis SWOT dan Product Life Cycle dapat menghasilkan personal brand serta konten media yang dapat meningkatkan awareness dan mengurangi tekanan college depression pada mahasiswa. Hasil dari perancangan menunjukan bahwa perasaan sendiri dapat menimbulkan banyak dampak buruk bagi mahasiswa yang sedang mengalami tekanan sehingga besar peran sosok teman dalam kehidupan mahasiswa, seseorang teman yang dapat mengerti memahami yang mereka rasakan sehingga mereka merasa tidak sendiri serta dapat menghibur untuk mengurangi tekanan mereka.
A randomized controlled trial of the web-based drinking diary program for problem drinking in multi workplace settings
Authors: Sunami Takashi , So Ryuhei , Ishii Hironobu , Sadashima Eiji , Ueno Takefumi , Yuzuriha Takefumi , Monji Akira
Published: January 2022

Objectives

To assess the effectiveness of a web-based brief intervention (BI) program to record daily drinking among people with problem drinking in workplace settings.

Methods

A two-armed, parallel-group, randomized controlled trial were conducted at six workplaces in Japan. After obtaining written consent to participate in the study, workers with an Alcohol Use Disorders Identification Test (AUDIT) score of 8 or higher were randomly assigned into two groups. The participants allocated to the intervention group recorded their daily alcohol consumption for 4 weeks using the program, while those allocated to the control group received no intervention. Outcome measures included the amount of alcohol consumption in past 7 days using the Timeline Follow-Back method in the program at baseline, 8th week, and 12th week and written AUDIT score at baseline and 12th week.

Results

Hundred participants were assigned to either the intervention group (n = 50) or control group (n = 50). The results of two-way repeated measures ANOVA showed a statistically significant interaction between the group and the week factors in the two primary outcomes (number of alcohol-free days, total drinks) and secondary outcomes (AUDIT score) (p = .04, .02, and .03, respectively). The between-group effect sizes (Hedges' g; 95% CI) of the outcomes at 12th week were 0.53; 0.13–0.93 (total drinks), 0.44; 0.04–0.84 (AUDIT score), 0.43; 0.03–0.83 (number of alcohol-free days).

Conclusions

The web-based BI program for problem drinking was considered to be effective in reducing alcohol consumption and the AUDIT score in workplace settings.
Flamines
Authors: Várhelyi Zsuzsanna
Published: January 2022

Flamines were Roman priests associated with the worship of individual deities – unlike groups among Roman priesthoods.
Sounds of Synthesis: Acoustic Real‐Time Analysis of Laser‐Induced Graphene
Authors: Li Victor D. , Li John T. , Beckham Jacob L. , Chen Weiyin , Deng Bing , Luong Duy X. , Kittrell Carter , Tour James M.
Published: January 2022

Laser‐induced graphene (LIG) can be patterned on a variety of substrates using a laser scriber/cutter. The quality and morphology of LIG is currently analyzed using Raman spectroscopy and electron microscopy. Here a method is presented to enable analysis of LIG in real‐time during the synthesis using a microphone attached to the laser writing head, followed by a simple acoustic signal processing scheme. It is demonstrated that it is possible to use the same energy input to simultaneously drive the conversion process and probe the formation of LIG in situ by applying Fourier and integral analyses, thus allowing rapid, high‐throughput determination of the local quality and morphology of the produced LIG.
Controlled Activation of TRPV1 Channels on Microglia to Boost Their Autophagy for Clearance of Alpha‐Synuclein and Enhance Therapy of Parkinson's Disease
Authors: Yuan Jiaxin , Liu Hanghang , Zhang Hao , Wang Tingting , Zheng Qing , Li Zhen
Published: January 2022

Parkinson's disease (PD) is characterized with accumulation of Lewy bodies with a major component of fibrillar alpha‐synuclein (α‐syn). Herein, boosting PD therapeutic efficacy by enhancing the autophagy of microglia to phagocytose and degrade α‐syn via controlled opening of their surface TRPV1 channels with rationally designed photothermal nanoagent is reported. The Cu2−xSe‐anti‐TRPV1 nanoparticles (CS‐AT NPs) are fabricated to target the microglia and open their surface TRPV1 channels under the second near infrared (NIR‐II) laser irradiation to cause influx of Ca2+ to activate ATG5 and Ca2+/CaMKK2/AMPK/mTOR signaling pathway, which promote phagocytosis and degradation of α‐syn. The CS‐AT NPs are efficiently delivered by focused ultrasound into striatum of PD mice with high expression of TRPV1 receptors. The athletic ability of PD mice treated by CS‐AT NPs and NIR‐II irradiation is significantly improved due to the phagocytotic clearance of α‐syn by microglia with enhanced autophagy. The enzyme tyrosine hydroxylase, ionized calcium binding adapter protein 1, glial fibrillary acidic protein, and pSer129‐α‐syn (p‐α‐syn) of treated PD mice are almost recovered to the normal levels of healthy mice. This study provides insights into the activation of microglial autophagy by targeting surface ion channels to improve the treatment of PD and other neurodegenerative diseases.
Highly Efficient and Flexible Scintillation Screen Based on Manganese (II) Activated 2D Perovskite for Planar and Nonplanar High‐Resolution X‐Ray Imaging
Authors: Shao Wenyi , Wang Xiang , Zhang Zhenzhong , Huang Jie , Han Zhongyuan , Pi Shuai , Xu Qiang , Zhang Xiaodong , Xia Xiaochuan , Liang Hongwei
Published: January 2022

X‐ray imaging technology covers a wide range of applications in the medical, industrial, and scientific research fields. Highly sensitive, flexible, and cost‐effective scintillation screens are of great importance for X‐ray imaging applications. In this paper, manganese (II) activated 2D butylammonium lead bromide perovskite, namely BA2PbBr4:Mn (II), is demonstrated as a highly efficient and low‐cost X‐ray scintillator. The appropriate amount of Mn (II) dopant can act as an activator for achieving the optimization of luminescence performance through efficient energy transfer. This produces a large Stokes shift thus almost eliminates the effect of self‐absorption. As a result, the optimal BA2PbBr4:10% Mn (II) perovskite scintillator demonstrates an ultrahigh sensitivity for X‐ray, with a high X‐ray scintillation light yield of up to 85 ± 5 photons keV−1 and low detection limits of 16 nGyair s−1 at the signal‐to‐noise ratio (SNR) of 3. Well‐resolved X‐ray images of several planar and nonplanar objects are obtained using a flexible large‐dimensional scintillation screen fabricated by blade‐coating strategy, featuring high spatial resolution of 10.7 lp mm−1 at modulation transfer function = 0.2. These results indicate that Mn (II) activated BA2PbBr4 perovskite with remarkable scintillation performances can serve as a highly promising scintillator for commercial high‐resolution X‐ray imaging applications.
UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease
Authors: Chen Guiqin , Ahn Eun Hee , Kang Seong Su , Xia Yiyuan , Liu Xia , Zhang Zhaohui , Ye Keqiang
Published: January 2022

Netrin‐1 is a chemotropic cue mediating axon growth and neural migration in neuronal development, and its receptors deletion in colorectal cancer and UNC5s act as dependence receptors regulating neuronal apoptosis. Asparagine endopeptidase (AEP) is an age‐dependent protease that cuts human alpha‐synuclein (α‐Syn) at N103 and triggers its aggregation and neurotoxicity. In the current study, it is reported that UNC5C receptor is cleaved by AEP in Parkinson's disease (PD) and facilitates dopaminergic neuronal loss. UNC5C is truncated by active AEP in human α‐SNCA transgenic mice in an age‐dependent manner or induced by neurotoxin rotenone. Moreover, UNC5C is fragmented by AEP in PD brains, inversely correlated with reduced netrin‐1 levels. Netrin‐1 deprivation in primary cultures induces AEP and caspase‐3 activation, triggering UNC5C proteolytic fragmentation and enhancing neuronal loss. Noticeably, blocking UNC5C cleavage by AEP attenuates netrin‐1 deprivation‐elicited neuronal death and motor disorders in netrin flox/flox mice. Overexpression of AEP‐truncated UNC5C intracellular fragment strongly elicits α‐Syn aggregation and dopaminergic loss, locomotor deficits in α‐SNCA transgenic mice. Hence, the findings demonstrate that netrin‐1 reduction and UNC5C truncation by AEP contribute to PD pathogenesis.
Synthesis of Substituted Pyrano[3,4‐b]Quinolines by Silver‐Catalyzed Regioselective Intramolecular Cyclization of 3‐Alkynylquinoline Aldehydes
Authors: Vani Damera , Chahal Kapil , Preethi Pagilla , Balasubramanian Sridhar , Rajender Reddy Kallu
Published: January 2022

A novel approach for the synthesis of regioselective pyrano[3,4‐b]quinolines from 3‐alkynylquinoline aldehydes with alcohols as nucleophiles has been elucidated. This protocol has shown high generality of functional group and provides the pyrano‐annulated products good to excellent yields. This methodology was adopted a new synthetic strategy to develop the 3‐alkynylquinolinealdehydes by using methanol as a C1 source.
Highly efficient NHC‐iridium(I) catalyzed disulfide bond forming reaction
Authors: Iali Wissam , Suleiman Rami K. , El Ali Bassam
Published: January 2022

The N‐heterocyclic carbene (NHC) iridium(I) complex [IrCl (COD)(IMes)] [IMes = 1,3‐bis(2,4,6‐trimethylphenyl) imidazole‐2‐ylidene] showed an excellent catalytic activity in the reactions of the aerobic oxidative coupling of thiols into disulfides. The use of oxygen of air as a green oxidant allows the thiols to be quantitatively converted into the corresponding disulfides under mild conditions and in a short reaction time. The replacement of chloride ligand on the iridium by the strong‐donating thiolate ligand yielded an electron‐rich and sensitive‐to‐oxygen active species [Ir(S‐R)(COD)(IMes)] at room light and subsequently promoting the catalytic oxidative coupling reactions. This active species was successfully isolated and characterized by X‐ray diffraction and found also to be essential in revealing a plausible mechanism for this Ir‐catalyzed transformation. The Density Functional Theory (DFT)‐calculated free energy profile of the proposed mechanism of our developed catalyst system can reasonably account for the key role of air in pursuing the catalytic reaction. Overall, the obtained computational and the experimental results of this study are in good agreement.
Synthesis and in vitro biological evaluation of novel water‐soluble porphyrin complexes for cancer photodynamic therapy
Authors: Hou Bingjie , Zhang Wenyuan , Li Cuili , Sun Xueqin , Feng Xiaoxia , Liu Jiacheng
Published: January 2022

In this study, we report the synthesis and biological evaluation of four novel cationic porphyrins (named as P1, P2, ZnP2, and CuP2) with potential as a photodynamic therapeutic agent. MTT experiments proved that P1, P2, and ZnP2 have high light toxicity and low dark toxicity for A549, H‐1975, and HepG2 cell lines. In addition, due to the specific targeting of porphyrin, there was only a weak toxicity to Hs 578Bst normal breast cancer cells. The study further confirmed the intracellular generation of reactive oxygen species (ROS) under light irradiation and ZnP2 could be effectively internalized by cells and also indicated that the photodynamic therapy effect achieved by ZnP2 and light irradiation can cause significant cell apoptosis. High relative singlet oxygen quantum yield and excellent phototoxicity ensure the optimal photosensitizer ZnP2 becomes potential candidates for photodynamic therapy drugs. Our results disclosed that the cationic porphyrin complexes used photodynamic therapy for the development of new and useful metal anticancer photosensitizer provide a strong platform.
Novel metformin complexes: Geometry optimization, non‐isothermal kinetic parameters, DNA binding, on–off light switching and docking studies
Authors: Shekhar Banoth , Rajeshwari Kasturi , Jayasree Boddula , Anantha Lakshmi Parupalli Venkata
Published: January 2022

Novel three water‐soluble chromium(III) complexes of types [Cr(Cl)(gly‐H)2(met)H2O] (1), [Cr(Cl)(met)(pro‐H)2H2O] (2) and [Cr(Cl)(his‐H)2(met)H2O] (3) (met = metformin, gly = glycine, pro = proline and his = histidine) have been synthesized. The geometrical structures have been shown to be octahedral, with substantial evidence from spectroanalytical techniques. Thermal investigations show the degradation pattern of the compounds from which the kinetic and thermodynamic parameters for the complexes' degradation were calculated using the Coats–Redfern 13 distinct kinetic models. The quantum chemical parameters were computed using the energies of the molecular orbital structures, developed from optimized geometrical structures, to evaluate the stability of the complexes. The groove binding of the complexes with CT‐DNA was confirmed by absorption and emission spectroscopy, viscosity measurements, gel electrophoresis and molecular docking studies.
Specializations of somatosensory innervation in the skin of humpback whales (Megaptera novaeangliae)
Authors: Eldridge Sherri A. , Mortazavi Farzad , Rice Frank L. , Ketten Darlene R. , Wiley David N. , Lyman Ed , Reidenberg Joy S. , Hanke Frederike D. , DeVreese Steffen , Strobel Sarah McKay , Rosene Douglas L.
Published: January 2022

Cetacean behavior and life history imply a role for somatosensory detection of critical signals unique to their marine environment. As the sensory anatomy of cetacean glabrous skin has not been fully explored, skin biopsy samples of the flank skin of humpback whales were prepared for general histological and immunohistochemical (IHC) analyses of innervation in this study. Histology revealed an exceptionally thick epidermis interdigitated by numerous, closely spaced long, thin diameter penicillate dermal papillae (PDP). The dermis had a stratified organization including a deep neural plexus (DNP) stratum intermingled with small arteries that was the source of intermingled nerves and arterioles forming a more superficial subepidermal neural plexus (SNP) stratum. The patterns of nerves branching through the DNP and SNP that distribute extensive innervation to arteries and arterioles and to the upper dermis and PDP provide a dense innervation associated through the whole epidermis. Some NF‐H+ fibers terminated at the base of the epidermis and as encapsulated endings in dermal papillae similar to Merkel innervation and encapsulated endings seen in terrestrial mammals. However, unlike in all mammalian species assessed to date, an unusual acellular gap was present between the perineural sheaths and the central core of axons in all the cutaneous nerves perhaps as mechanism to prevent high hydrostatic pressure from compressing and interfering with axonal conductance. Altogether the whale skin has an exceptionally dense low‐threshold mechanosensory system innervation most likely adapted for sensing hydrodynamic stimuli, as well as nerves that can likely withstand high pressure experienced during deep dives.
Improving the effectiveness of voice search systems through partial query modification
Authors: Sa Ning , Yuan Xiaojun (Jenny)
Published: January 2022

This paper addresses the importance of improving the effectiveness of voice search systems through partial query modification. A user‐centered experiment was designed to compare the effectiveness of an experimental system using partial query modification feature to a baseline system in which users could issue complete queries only, with 32 participants each searching on eight different tasks. The results indicate that the participants spent significantly more time preparing the modification but significantly less time speaking the modification by using the experimental system than by using the baseline system. The participants found that the experimental system (a) was more effective, (b) gave them more control, (c) was easier for the search tasks, and (d) saved them time than the baseline system. The results contribute to improving future voice search system design and benefiting the research community in general. System implications and future work were discussed.
Combining recombinase polymerase amplification and DNA‐templated reaction for SARS‐CoV‐2 sensing with dual fluorescence and lateral flow assay output
Authors: Farrera‐Soler Lluc , Gonse Arthur , Kim Ki Tae , Barluenga Sofia , Winssinger Nicolas
Published: January 2022

The early phase of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic was exacerbated by a diagnostic challenge of unprecedented magnitude. In the absence of effective therapeutics or vaccines, breaking the chain of transmission through early disease detection and patient isolation was the only means to control the growing pandemic. While polymerase chain reaction (PCR)‐based methods and rapid‐antigen tests rose to the occasion, the analytical challenge of rapid and sequence‐specific nucleic acid‐sensing at a point‐of‐care or home setting stimulated intense developments. Herein we report a method that combines recombinase polymerase amplification and a DNA‐templated reaction to achieve a dual readout with either fluorescence (microtiter plate) or naked eye (lateral flow assay: LFA) detection. The nucleic acid templated reaction is based on an SNAr that simultaneously transfers biotin from one Peptide Nucleic Acid (PNA) strand to another PNA strand, enabling LFA detection while uncaging a coumarin for fluorescence readout. This methodology has been applied to the detection of a DNA or RNA sequence uniquely attributed to the SARS‐CoV‐2.