bluuebunny/crossref_metadata_2025 huggingface dataset:
PENENTUAN WAKTU BAKU PEMBUATAN DODOL DI PD.NESIF DENGAN MENGGUNAKAN METODE JAM HENTI UNTUK MENINGKATKAN PRODUKTIVITAS
Authors: Nurwathi Nurwathi , Azwar Ade Geovania , Ramadhani Agung
Published: April 2022

Proses Produksi yang baik menggunakan informasi awal dalam proses produksi yakni waktu baku. Waktu Baku penyelesaian suatu pekerjaan adalah waktu yang dibutuhkan secara wajar oleh seorang pekerja normal untuk menyelesaikan suatu pekerjaanyang dijalankan dalam system kerja terbaik. PD NESIF sebagai UMKM yang memiliki Produk Unggulan yakni Dodol Garut. PD NESIF belum pernah menghitung waktu baku sebagai bagian dari proses produksi. Sebagai salah satu Produk Unggulan PD NESIF, yang jangkauan pemasarannya adalah Seluruh wilayah Jawa Barat dan Yogjakarta, adalah penting untuk mengetahui Waktu Baku dari Proses Produksi Dodol. Beberapa waktu yang turut dihitung dalam penelitian ini adalah Waktu Baku, Waktu siklus dan Waktu Normal. Tujuan Penelitian ini adalah untuk memberikan perhitungan waktu baku pada produksi Dodol dan diharapkan dapat meningkatkan produktivitas PD Nesif. Metode yang digunakan dalam menentukan waktu baku pada penelitian ini adalah menggunakan teknik pengukuran waktu secara langsung yaitu cara jam henti (stopwatch). Hasil penelitian menunjukkan bahwa Perhitungan waktu baku pada proses produksi Dodol di PD Nesif adalah Pemotongan dodol untuk 1 Nampan 424 detik (7,4 menit), Pembungkusan 1 Satuan Dodol 12 detik, Pembungkusan 1pack (1kg) dodol 116 detik (1,56 menit), dan Press 1 Pack Dodol 28,72 detik atau 29 detik. Waktu baku 1 potong dodol adalah 13,76 detik + 1,92 detik + 12 detik + 4,46 detik + 1,11 detik = 33,25 Detik.
IMPLEMENTASI SPMI, KUALITAS MANAJEMEN, KINERJA SEKOLAH DAN IMPLIKASINYA TERHADAP REPUTASI SEKOLAH DI SMKN 5 BANDUNG
Authors: Rochanah Sity , Mulyani Sri Rochani , Mulyanti Dety
Published: April 2022

Kualitas satuan pendidikan dapat berkembang jika satuan pendidikan menerapkan penjaminan mutu dalam pengelolaan proses-proses di dalamnya dalam pemenuhan 8 (delapan) Standar Nasional Pendidikan. Penelitian ini bertujuan untuk mengukur Implementasi Sistem Penjaminan Mutu Internal (SPMI) dan Kualitas Manajemen Sekolah terhadap Kinerja Sekolah dan Implikasinya terhadap Reputasi Sekolah ( Studi Kasus di Sekolah Menengah Kejuruan  Negeri 5 Bandung. Metode penelitian yang digunakan adalah metode kuantitatif.Hasil penelitian menunjukkan Implementasi SPMI termasuk skor   katagori sangat baik,Kualitas Manajemen termasuk  katagori sangat baik,Kinerja Sekolah termasuk  katagori sangat baik dan  Reputasi Sekolah  termasuk katagori sangat baik.Untuk hasil data analisis diperoleh bahwa secara langsung menunjukkan bahwa Implementasi SPMI (X1) berpengaruh sebesar 0,482 terhadap Kinerja sekolah(Y),  Kualitas Manajemen (X2) berpengaruh sebesar 0,350 terhadap kinerja sekolah(Y), Kinerja sekolah(Y) berpengaruh sebesar 0,275 terhadap Reputasi sekolah(Z), Implementasi SPMI(X1) berpengaruh sebesar 0,354 terhadap Reputasi Sekolah(Z) dan Kualitas Manajemen(Y) berpengaruh sebesar 0,323 terhadap Reputasi Sekolah(Z) .Adapun Pengaruh secara tidak langsung menujukkan bahwa Implementasi SPMI(X1) terhadap Reputasi sekolah melalui Kinerja Sekolah (Y) sebesar 13,26%, dan Kualitas Manajemen (X2) terhadap Reputasi sekolah melalui Kinerja Sekolah(Y) berpengaruh sebesar 9,63% .Kata Kunci : Implementasi SPMI, Kualitas Manajemen, Kinerja Sekolah, Reputasi Sekolah.
PREDIKSI VOLUME DAN RITASI PENGELOLAAN SAMPAH DI KOTA BANDUNG DENGAN METODE REGRESI LINEAR
Authors: . Gunawansyah , Laluma Riffa Haviani , Prasetya Alka
Published: April 2022

Permasalahan sampah sudah menjadi masalah serius di berbagai kota besar khususnya Bandung.  Pertumbuhan penduduk dan gaya hidup masyarakat menjadi faktor terbesar dalam menyumbang volume sampah. Hal ini semakin memiliki dampak besar pada saat pengelolaannya tidak dilakukan secara profesional. Volume sampah dalam 10 tahun terakhir meningkat 71% dan hal ini berdampak pada ketersediaan TPS, TPA, petugas dan anggaran biaya.  Berbagai antisipasi dan pengendalian dini harus segera dilakukan seperti edukasi kepada masyarakat maupun profesionalisme dalam pengelolaan sampah. Prediksi volume sampah dan ritasi pengangkutan sampah bulanan maupun tahunan dengan menggunakan berbagai metode statistik seperti regresi linear bisa digunakan untuk memprediksi dan merancang berbagai hal teknis dalam pengelolaan sampah. Hasil dari prediksi tersebut bisa digunakan untuk memutuskan berbagai kebijakan jangka pendek maupun jangka panjang oleh pihak terkait khususnya PD Kebersihan Kota bandung. Hasil prediksi volume sampah tahun 2021 dan 2022 dengan menggunakan metode regresi linear berdasarkan data tahun 2011-2020 sebesar 489.148 ton dan 506.709 ton. Hasil prediksi ritasi pengangkutan sampah untuk tahun 2020 sebanyak 100.042 kali atau rata-rata 274 ritasi/hari dan 103.819 kali untuk tahun 2022 atau rata-rata 284 ritasi/hari. Rata-rata volume sampah yang di angkut/ritasi sebesar 4,89 ton untuk tahun 2021 dan 4,88 ton pada tahun 2022.  Hasil prediksi tersebut bisa digunakan untuk menyusun anggaran biaya, perencanaan ketersediaan dan daya tampung TPS, TPA serta petugas kebersihan.
ANALISIS TINGKAT BEBAN KERJA MENTAL, STRES, DAN KELELAHAN ORANG TUA SELAMA MENDAMPINGI ANAK DALAM PEMBELAJARAN DARING DI MASA PANDEMI COVID-19
Authors: Husniyyah Shinta Nuraeni , Azwar Ade Geovania
Published: April 2022

Pandemi Covid-19 sangat berdampak pada kehidupan masyarakat, salah satunya berdampak pada bidang pendidikan yang menyebabkan proses pembelajaran diganti menjadi pembelajaran daring. Dalam proses pembelajaran daring bagi peserta didik wajib belajar 12 tahun, sangat dibutuhkan pendampingan orang tua, tetapi kenyataannya pendampingan yang harus dilakukan di rumah membuat banyak orang tua kewalahan. Penelitian ini bertujuan untuk mengetahui tingkat beban kerja mental orang tua, tingkat stres orang tua, serta tingkat kelelahan orang tua selama mendampingi anak dalam pembelajaran daring di masa pandemi Covid-19. Objek pada penelitian ini ialah orang tua yang memiliki anak bersekolah di Kota Bandung serta mendampingi anak dalam pembelajaran daring. Metode yang digunakan untuk mencari tingkat beban kerja mental yaitu dengan kuesioner NASA-TLX, untuk mencari tingkat stres dengan kuesioner DASS-21, dan untuk mencari tingkat kelelahan dengan kuesioner SOFI. Hasil penelitian menunjukkan beban kerja yang diterima oleh orang tua yang mempunyai anak jenjang SD adalah 71,67, anak jenjang SMP 70,68, dan anak jenjang SMA 74,45. Secara keseluruhan tingkat stres orang tua sebanyak 185 orang berada pada kategori normal. Tingkat kelelahan orang tua yang mempunyai anak jenjang SD, anak jenjang SMP, dan anak jenjang SMA berada pada kategori sedang.
Emotional Intelligence of Early Childhood Parents During the Covid-19 Pandemic in Indonesia
Authors: Dhieni Nurbiana , Mayuni Ilza , Juriana Juriana
Published: April 2022

Many cases of violence in early childhood during the Covid-19 epidemic were carried out by their own parents. This is closely related to the emotional intelligence of early childhood parents, which is a reflection of their emotional literacy. This study aims to determine the emotional intelligence of early childhood parents in Indonesia at the time of Covid-19, with a sample of 641 early childhood parents living in the capital city of Jakarta. Data were collected using a questionnaire based on Daniel Goleman's five dimensions of emotional intelligence, namely: self-awareness, self-regulation, self-motivation, empathy, and work together. Analysis techniques used descriptive and inferential quantitative data analysis. The validity of the instruments ranged from 0.323 to 0.603 with reliability of r = 0.625 to 0.731. The results showed that most of the emotional intelligence of early childhood parents in Indonesia during the Covid-19 pandemic was in the sufficient category (78%). The absence of a correlation between work together with self-awareness (F = -0.026; p> 0.05), self-regulation (F = 0.005; p> 0.05), and empathy (F = 0.002; p> 0.005) indicated that parents still need to increase their self-sensitivity and empathy for their children so that they can do positive parenting during the Covid-19 pandemic.
Effect of pioglitazone treatment on serum chemerin and vaspin levels in polycystic ovary syndrome.
Authors: Rana Hussein Kutaif  , Mustafa G. Alabbassi  , Weqar Akram Hussein  , Zainab Faleh Ali  , Shatha Khayun Jassim
Published: April 2022

Abdominal fat synthesizes a variety of adipokines, including vaspin and chemerin, that affect the resistance to insulin. This research was conducted to demonstrate the effect of pioglitazone, one insulin sensitizer used to decrease insulin resistance, on these adipokines in

 

obese patients with polycystic ovary (PCOS). Twenty-five obese women with PCOS were treated with pioglitazone 15mg/bid for 12 weeks. Modifications in fasting blood glucose (FBG), serum fasting insulin (FSI), chemerin and vaspin serum levels, follicle stimulation hormone (FSH), luteinizing hormone (LH), testosterone (T), and in baseline and post-therapy were assessed. Body mass index decreased without any substantial variance after 12 weeks of pioglitazone therapy (P> 0.05). T, FSI, HOMA-IR, LH, and FBG levels have decreased considerably (P≤0.01, P≤0.05) after the therapy. No substantial variations were found in FSH (P>0.05). Serum chemerin and vaspin levels were observed no significant difference than before treatment (P>0.05) in obese women with polycystic ovarian syndrome cases.
Study the antibacterial effect of N_butanol extract of Urtica dioica
Authors: Ahmed Abdulaziz Ahmed  , Baydaa Hameed Abdulah  , Yaser Mustafa Kamal
Published: April 2022

Since ancient times Urtica dioica has been used as an herbal medicine in Western Asia. The current study demonstrates the anti-bacterial effect of N_butanol extraction of Urtica dioica. The antibacterial effect was tested against some of gram-positive bacteria and gram-negative bacteria isolated

 

from hospitalized patients having urinary tract infection. Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia and Pseudomonas aeruginosa was used. Urticasea is a family of plant known for their medicinal activity from folk medicine. Urtica dioica is a member of urticasea and it is known for it is antibacterial effect.

Methods

The leaves of Urtica dioica were collected in Iraq from jisr dayla district in Baghdad province in april 2019.The N_butanol extraction was compared with the drug ciprofloxacin. Disc diffusion method was used to determine the sensitivity of the samples.

Results

The N_ butanol extract shows weak inhibitory effect on Escherichia coli while other strain does not affect by extract comparing with ciprofloxacin.

Conclusion

The N_butanol extract of urtica dioica have weak antibacterial effect when compared with ciproflxacine
Nano-carriers as a Selective Treatment for Cancer
Authors: Ghaidaa S. Hameed  , Methaq Hamad Sabar
Published: April 2022

Among many therapeutic treatments for cancer, nano-carriers are the focus of our review to illustrate the update usage of this drug delivery approach, the most likely side effects and the reality of their potential application with minimum adverse effects. Here, we demonstrate the types of these nano-carriers based on

their nature with detailed recent studies about their use. The variation in the skeleton of these nanoparticles enable the selection of the suitable type with higher specifications than others.  However, the poor in vivo testing is the main stumbling block for completion of their manufacturing. This review will help the researchers to find the road map for further investigation to finally aid the pharmaceutical companies in manufacturing these nano-carriers in appropriate dosage forms to save the life of millions of people in the world.
The Impact of Vitamin D on The Development of Multiple Sclerosis (Review article)
Authors: Aseel Ghassan Daoud  , Huda Jaber Waheed  , Mayssaa Essam Abdala
Published: April 2022

Multiple Sclerosis is a harmful disease causes severe and painful symptoms. In the recent period, researchers have tended to study the effect of vitamin D deficiency on general health. Several studies have reported that there is a relation between vitamin D levels and MS disease progression. Epidemiological testimony

and reports have recorded that there are an association between the decrement in plasma vitamin D levels and the incidence of MS also with the disease development; and it has seen that when take vitamin D as supplement may protect the MS patients against disease development. Despite clear evidence of the correlation between disease progression and vitamin D deficiency but the mechanism yet unclear.
Mediaciones para la adquisición del código escrito
Authors: Gómez López Luis Felipe , Valdés Dávila Ma. Guadalupe , Centeno Partida María de Lourdes
Published: April 2022

En este artículo se analizan las intervenciones mediacionales utilizadas en el desarrollo de la lectoescritura inicial en un grupo de nueve niños que presentan dificultades para su adquisición, pertenecen a familias de bajos recursos económicos y que habitan en colonias del sur de la zona metropolitana de Guadalajara. El método utilizado fue un estudio cualitativo de caso. El objeto de análisis fueron las sesiones de clase realizadas durante el primer semestre del 2019 en un centro de atención comunitaria. Para el análisis y la interpretación se utilizó el marco teórico del constructivismo sociocultural. Los datos recabados permitieron identificar doce acciones mediacionales agrupadas en tres grandes categorías: el sentido de la actividad y sentirse competentes, la enseñanza directa y el fomento de procesos reflexivos por parte de los niños. Se concluye que las acciones mediacionales ayudaron al aprendizaje de los estudiantes, pero que hizo falta un mayor seguimiento individual de cada uno para lograr mejores resultados.
Comparative Analysis of Methods for Estimating the Deposition of Radioactive Aerosols in Sampling Systems at Nuclear Power Facilities
Authors:   Sosny Research&Development Company, Dimitrovgrad, Russia, Kocherygin M.V. , Lachugin A.V. ,   Sosny Research&Development Company, Dimitrovgrad, Russia, Pavlov S.V. ,   Sosny Research&Development Company, Dimitrovgrad, Russia
Published: April 2022

Purpose: To analyze the existing computational methods for estimating aerosol losses in sampling systems at nuclear energy use facilities, presented in domestic and foreign regulatory documentation and technical literature, in order to form proposals for practical optimization of the use of these computational algorithms. Results: Methods for calculating the loss of aerosol particles in air sampling systems from pipes, ventilation systems and premises of nuclear energy facilities are considered. A comparative analysis of methods for estimating aerosol losses considered in Russian and foreign regulatory and technical documentation is performed. The basics of aerosol mechanics are briefly considered. On the basis of the conducted research, the possible applications of the considered methods for estimating aerosol losses in the design for various initial situations are considered. The expediency and prospects of developing clear computational algorithms for use in the design and operation of sampling systems are considered
Human Mesenchymal Stromal Cells: Characteristics, Radiosensitivity and Effects of Low-Dose Radiation
Authors:   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Usupzhanova D.Yu. , Astrelina T.A. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Kobzeva I.V. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Brunchukov V.A. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Samoilov A.S. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Published: April 2022

Throughout life a person is inevitably exposed to low doses of ionizing radiation (LDIR) both background radiation and as part of medical treatment and diagnostics, during professional activities, air travel etc. Today the effects of LDIR and the risks of long-term consequences of this impact are increasingly attracting the researchers attention. On the one hand, scientists point to the development of negative consequences, in particular, the accumulation of double-stranded breaks DNA, on the other hand, some studies demonstrating the development of such events as hormesis and adaptive response. Based on this, there is an assumption that in the range of LDIR may exist a non-linear dependence of the effects on the radiation dose, i.e. the effect isn’t proportional to the received dose and that is consistent with the threshold-concept. Today many scientific papers are devoted to this area of research. Special attention is drawn to the effects LDIR on human mesenchymal stromal cells (MSCs) because they are the regenerative reserve of the body. Due to the them ability to self-sustain MSCs can stay in the body for a long time and undergo several rounds of irradiation, accumulating the changes in themselves and passing ones to the next generations of cells since they have the potential to the differentiation. Thus, changes that have occurred in the MSCs affect the human body as a whole. Based on all of the above, it can be concluded that the study of the effects of LDIR on mesenchymal stromal cells of human is actual area of research currently.
Reference and Information Complex REGISTR of the Urals Research Center for Radiation Medicine of the FMBA of Russia
Authors:   Urals Research Center for Radiation Medicine, Chelyabinsk, Russia, Startsev N.V. , Shishkina E.A. ,   Urals Research Center for Radiation Medicine, Chelyabinsk, Russia,   Chelyabinsk State University, Chelyabinsk, Russia, Blinova E.A. ,   Urals Research Center for Radiation Medicine, Chelyabinsk, Russia,   Chelyabinsk State University, Chelyabinsk, Russia, Akleyev A.V. ,   Urals Research Center for Radiation Medicine, Chelyabinsk, Russia,   Chelyabinsk State University, Chelyabinsk, Russia
Published: April 2022

Currently, the Urals Research Center for Radiation Medicine has collected arrays of socio-demographic, dosimetric and medical and biological information. The manuscript presents reference and information complex REGISTR recently developed in the URCRM to optimize the use of multiple registers and data bases. The development of reference and information complex enabled to significantly increase the use of various information resources, and provides strategic planning of new integral studies. A description of archive and actual registers and data bases of the URCRM scientific departments is presented in the manuscript. The issues of possible integration of information saved in various formats were addressed. The manuscript shows that a unified system of coding patients can be treated as a way of integration of information. The manuscript contains a capability description of reference and information complex REGISTR for facilitating research planning and possibility of integration of information obtained in different URCRM scientific departments. A technical implementation of the complex development was described. The article shows an illustration of how the REGISTR complex was used for planning of the research performed in the Laboratory of Molecular and Cellular Radiobiology. The development direction of REGISTR complex was considered.
Stereotactic Body Radiation Therapy (SBRT) in Patients with Head and Neck Cancer Treatment. Current State of the Problem
Authors:   P.A. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Moscow, Russia, Gevorkov A.R. , Boyko A.V. ,   P.A. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Moscow, Russia, Kaprin A.D. ,   P.A. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Moscow, Russia
Published: April 2022

This publication provides an overview of the current state of the art in the use of stereotactic radiation therapy (SBRT) for patients with head and neck tumors. We have analyzed current trends, and also presented the features of radiobiology and the basic principles of radiation treatment. Special attention is paid to indications for SBRT, fractionation schemes and radiation planning. The use of SBRT for primary head and neck tumors, including boost, as well as relapses treatment are described. The results of the implementation of SBRT by various authors both as an independent option and in combination with drug therapy are presented. The efficacy and tolerance of radiation is described in a summary form with clarifying comments. The radiation therapy toxicity profile is detailed, including the main risk factors of postradiation complications.
Hyperthermic Methods in Conservative and Palliative Treatment of Oncological Patients. Part 1. Loco-Regional Hyperthermia
Authors:   Siberian Scientific Research Institute of Hyperthermia, Novosibirsk, Russia., Kurpeshev O.K. , Van Der Zee J. ,   Erasmus Medical Centre, Cancer Institute, Rotterdam, The Netherlands
Published: April 2022

The analysis of the results of conservative and palliative treatment of cancer patients with the use of loco-regional hyperthermia (LRHT) alone or in combination with various methods of anticancer therapy was carried out. The data obtained showed that LRHT significantly increases the immediate results of radiation and / or chemotherapy, has a pronounced palliative effect, and in some cases provides long-term local control. In incurable patients who have exhausted the "limit" of chemotherapy and / or radiation therapy, its use for palliative purposes is also possible in mono-mode.
Case of a Patient with Cervical Cancer after Wertheim Surgery who Underwent Minimally Invasive Treatment of Giant Lymphocele and Related Secondary Complications
Authors:   National Medical Research Radiological Center, Moscow, Russia, Skreptsova N.S. , Stepanov S.O. ,   National Medical Research Radiological Center, Moscow, Russia, Kaprin A.D. ,   National Medical Research Radiological Center, Moscow, Russia, Kostin A. A. ,   National Medical Research Radiological Center, Moscow, Russia, Boyko A.V. ,   National Medical Research Radiological Center, Moscow, Russia, Demidova L.V. ,   National Medical Research Radiological Center, Moscow, Russia, Novikova E.G. ,   National Medical Research Radiological Center, Moscow, Russia, Mitina L.A. ,   National Medical Research Radiological Center, Moscow, Russia, Dolgacheva D.V. ,   National Medical Research Radiological Center, Moscow, Russia, Zelich N.V. ,   National Medical Research Radiological Center, Moscow, Russia, Serova L.G. ,   National Medical Research Radiological Center, Moscow, Russia
Published: April 2022

An experience of successful treatment of giant lymphocele and related secondary complications, such as signs of hydronephrosis of both kidneys of a patient after Wertheim surgery in case of cervical disease before radiotherapy is described. A complex of ultrasound studies using 3 types of echographic picture of the lymphocele was applied, which made it possible to determine the rational management of the patient using the technique of invasive sonography. Ultrasound examination, on the 17th day after the operation, revealed lymphocele in the iliac regions (1450 ml on the right, 1290 ml on the left) and signs of hydronephrosis of both kidneys. Drains under the control of sonography in both the lymphatic cavity were set up. Signs of hydronephrosis of both kidneys ceased to be located on the 2nd day after the installation of drains. Drains were removed after 13 days. During further ultrasound examinations of the patient, the lymphocele and signs of hydronephrosis were not rendered. Ultrasound examinations were performed on the 3rd, 7th, 12th, 21st, 35th, 62nd, 145th day after drains were removed.
Implementasi Penguatan Pendidikan Karakter (PPK) Pada Mata Pelajaran PJOK di Sekolah Dasar Islam Terpadu Kabupaten Lebong
Authors: Medika Fatria , Syafrial Syafrial , Sutisyana Ari
Published: April 2022

This study aims to describe the implementation of strengthening character education (PKK) in PJOK subjects. This research is a qualitative descriptive study. The method used in this research is a survey method. The instrument used was a questionnaire. The composed instruments were consulted with an expert (expert judgment). The subjects in this study were PJOK teachers and SDIT students of Lebong Regency with a total of 3 PJOK teachers and 45 students. The data analysis technique used is descriptive analysis with a percentage. The results showed that the implementation process of strengthening character education (PPK) in corner subjects at the Integrated Islamic Elementary School in Lebong Regency, namely the religious character value of 94%, the nationalist value 89%, the independent value 95%, the mutual cooperation value 94% and the integrity value 95% .
Perbandingan latihan power otot tungkai dan latihan ball feeling terhadap tingkat akurasi passing sepak bola di SSB Kota Bengkulu
Authors: Rachman Muhammad Arif , Raibowo Septian , Prabowo Andika
Published: April 2022

Tujuan penelitian adalah untuk mengetahui pengaruh latihan power otot tungkai terhadap akurasi passing, mengetahui pengaruh latihan ball feeling terhadap akurasi passing, mengetahui manakah yang lebih efektif antara latihan power otot tungkai dan ball feeling terhadap akurasi passing sepak bola. Desain penelitian ini menggunakan two group pre test – post test group design. Populasi 118 atlet dan sampel 30 orang. Penelitian ini menggunakan teknik pengambilan sampel bertujuan (purposive sampling). Teknik pengumpulan data yang digunakan adalah teknik tes dan pengukuran. Tes yang digunakan adalah tes passing. Hasil penelitian ini, pertama tidak terdapat pengaruh latihan power otot tungkai terhadap akurasi passing sepak bola t_hitung = 1.509 <  t_tabel = 2.160, kedua terdapat pengaruh latihan ball feeling terhadap akurasi passing sepak bola t_hitung = 2.507 >  t_tabel = 2.160, hasil uji perbandingan antara 2 kelompok eksperimen memperoleh hasil t_hitung = 0.665 < t_tabel  = 2.048, dan ketiga dapat disimpulkan bahwa tidak terdapat perbedaan yang signifikan antara latihan power otot tungkai dan latihan ball feeling. Persentase latihan ball feeling sebesar 13.98%, sedangkan persentase peningkatan latihan power otot tungkai sebesar 10.99%. Sehingga dapat direkomendasikan bahwa latihan ball feeling lebih baik dari pada latihan power otot tungkai.
Survei sarana dan prasarana pembelajaran pendidikan jasmani olahraga dan kesehatan pada sekolah menengah kejuruan negeri se-kecamatan Argamakmur
Authors: Prasetyo Agung , Pujianto Dian , Yarmani Yarmani
Published: April 2022

Penelitian ini bertujuan untuk mengetahui survei sarana dan prasarana pembelajaran pendidikan jasmani olahraga dan kesehatan pada Sekolah Menengah Kejuruan Negeri Se-Kecamatan Argamakmur. Jenis Penelitian ini adalah penelitian deskriptif kualitatif. Penelitian ini adalah penelitian survei sarana dan prasarana yang ada disekolah. Teknik pemilihan subjek penelitian menggunakan purposive sampling. Subjek penelitian ini adalah 2 orang guru olahraga. Instrument dan teknik pengumpulan data yang digunakan dalam penelitian ini adalah observasi, wawancara dan dokumentasi. Teknik analisis data yang digunakan adalah analisis deskriptif kualitatif dengan presentase. Hasil penelitian survei menyatakan bahwa presentase pada SMKN 1 dan SMKN 2 rata-rata penilaian menunjukan komponen cabang olahraga atletik dengan presentase (52,78%), cabang olahraga permainan dengan presentase (90,78%), cabang olahraga ritmik dengan presentase (12,50%) dan hasil jumlah data keseluruan (52,02%) hasil ini didukung oleh data dokumentasi. Berdasarkan hasil penelitian dapat disimpulkan bahwa Sarana dan Prasarana Pembelajaran Pendidikan Jasmani Olahraga dan Kesehatan Pada Sekolah Menengah Kejuruan Negeri Se-Kecamatan Argamakmur cukup ideal.
Proses pembelajaran pendidikan jasmani olahraga dan kesehatan (pjok) di slb kota bengkulu di masa pandemi covid-19
Authors: Wiratama Ahmad Doni , Raibowo Septian , Prabowo Andika
Published: April 2022

Penelitian ini bertujuan untuk mengetahui bagaimana Proses pembelajaran PJOK terhadap ranah afektif, kognitif, dan psikomotorik. Masalah yang terjadi adalah belum diketahui penilaian yang dilakukan guru PJOK di masa pandemi Covid-19 pada SLB Kota Bengkulu. Penelitian ini merupakan penelitian kualitatif dengan metode deskriptif, teknik pengumpulan data yang digunakan diantaranya observasi, kuisioner dan dokumentasi. Teknik analisis data menggunakan skala likert. Subjek penelitian ini sebanyak 6 orang guru PJOK. Penelitian ini dilaksanakan di SLB Kota Bengkulu. Hasil penelitian menunjukkan guru PJOK melakukan penilaian: 1) ranah afektif berada pada kategori baik dengan persentase sebesar 78,33%, 2) penilaian kognitif berada pada kategori baik dengan persentase sebesar 80,33%, 3) penilaian ranah psikomotorik juga berada pada kategori baik dengan persentase sebesar 79,67%. Berdasarkan hasil penelitian secara keseluruhan dapat disimpulkan bahwa proses pembelajaran PJOK terhadap pembelajaran daring dalam mata pelajaran Pendidikan Jasmani Olahraga dan Kesehatan pada Masa Pandemi Covid-19 hasil tersebut dinyatakan baik.
STUDY CORRELATION BETWEEN BURDEN AND QUALITY OF LIFE OF DEPENDENT ELDERLY CAREGIVERS IN KLITREN, YOGYAKARTA
Authors:   Duta Wacana Christian University Indonesia, Kristina Hana , Widagdo The Maria Meiwati ,   Duta Wacana Christian University Indonesia, Perdamaian Teguh Kristian ,   Duta Wacana Christian University Indonesia
Published: April 2022

Introduction: Elderly with disability need caregiver’s assistance in their activities of daily living. The caregiver can experience burden during caring for dependent elderly. The burden can affect caregiver’s quality of life. Objectives: to measure and test the correlation between dependent elderly’s caregiver burden and quality of life in Klitren Kampong, Gondokusuman District, Yogyakarta Municipality. Materials and Methods: The subjects were primary informal caregivers aged ≥ 18 years with good cognitive functions who caring for the elders with ADL score <12. Respondents were selected using consecutive sampling technique. This is a quantitative research with cross-sectional study design. Zarit Burden Interview and Caregiver Reaction Assessment were used to assessing caregiver’s burden. WHO Quality of Life-BREF was used to assess caregiver’s quality of life. Data was analysed using spearman’s rank correlation. Results: There were 21 female study subjects. In each of the CRA and ZBI domains, the caregivers’ burden tend to be low (mean=8.63±10.730–72.42±10.983). Caregivers’ quality of life tend to be low (mean=49.76±11.962–60.76±11.726). There is a strong and statistically significant correlation between the impact on finance (p=0.000, ρ=-0.678) and impact on health (p=0.002, ρ=-0.602) domain on CRA with the environmental domain of WHOQoL-BREF. There is a strong and statistically significant correlation between the impact on schedule domain on CRA with the psychological domain of WHOQoL-BREF (p=0,000, ρ=-0.683). Conclusion: There are significant correlations between caregivers’ burden and quality of life especially on certain domains. Caregivers with higher burden have lower quality of life.
THE CORRELATION OF TWO MONTHS FULL OF BREASTFEEDING ON EARLY INITIATED BREASTFEEDING GROUP WITH PUERPERIUM BLEEDING
Authors:   Faculty of Medicine, Widya Mandala Catholic University, Surabaya Indonesia, Masta, Putu Cantika Jenise Asri , Prabantoro Benedictus Triagung Ruddy ,   Department of Obstetrics and Gynecology, Faculty of Medicine, Widya Mandala Catholic University, Surabaya Indonesia, Pangemanan Lisa ,   Department of Pediatrics, Faculty of Medicine, Widya Mandala Catholic University, Surabaya Indonesia
Published: April 2022

Background: Postpartum bleeding is one of the main causes of mortality in mothers in 2017. Based on Profil Kesehatan Provinsi Jawa Timur's data in 2017, about 28,26% of mothers' mortality percentage is because of postpartum bleeding. Some of the factors affecting the duration of puerperium bleeding are the initiation of early breastfeeding and exclusive breastfeeding. Early breastfeeding initiation can stimulate the oxytocin hormone to contract the uterine and help complete the extrusion of the placental site and sloughing of decidua tissue (lochia). Objective: This study aims to know the correlation of 2 months full of breastfeeding on early initiated breastfeeding group with puerperium bleeding. Method: This study is an observational analytical study where the design is cohort retrospective, and the 60 samples used in this research are taken with simple random technique sampling. This research was carried out by collecting information from secondary data, and the whole process was done in Gotong Royong Hospital Surabaya from July to September 2020. This research used the Mann-Whitney U test to analyze and find the correlation of both variables. Results: Based on the statistic test, there is no correlation between both variables, resulting in p = 0,211. Conclusion: there is no significant correlation between 2 months full of breastfeeding on the early initiated breastfeeding group with puerperium bleeding.
HUBUNGAN KEJELASAN DAN KELENGKAPAN PENULISAN DIAGNOSA PENYAKIT BRONCHITIS ACUTE DENGAN KETEPATAN PENGODEAN DIAGNOSA PENYAKIT BERDASARKAN ICD 10 DI BANGSAL RAWAT INAP PENYAKIT DALAM RS MITRA MEDIKA BATANG HARI
Authors: Maisharoh Maisharoh , Sari Dian , Rosanti Dea
Published: April 2022

Coding is one of the medical record data processing activities in providing codes with letters or numbers or a combination of letters and numbers that represent data components. Of the 10 medical record files selected at random, 6 (60%) files were found to be coding inaccuracy, while 4 (40%) files were in accordance with ICD-10. The purpose of this study was to determine the accuracy of the diagnosis code for acute bronchitis in inpatients in the internal medicine ward at Mitra Medika Batanghari Hospital. This type of research uses a descriptive method with a quantitative approach. The population is 95 medical record documents for inpatient acute bronchitis. This research was conducted in July 2021. The sampling technique used a saturated sample. Data analysis used bivariate analysis with SPSS program. The results showed that there were 56 (58.9%) medical records that were not accurate in coding the diagnosis of acute bronchitis for inpatients in the internal medicine ward, 42 (44.2%) medical records for the clarity of writing a diagnosis of acute bronchitis for inpatients in the medical ward. in which it is not clear and 35 (36.8%) medical records completeness of writing a diagnosis of acute bronchitis in inpatients in an internal medicine ward that are incomplete, and the results of bivariate analysis show that there is a relationship between clarity and accuracy of diagnostic coding pvalue = 0.001 (p<0 ,05). and there is a relationship between clarity and completeness with the accuracy of diagnostic coding pvalue = 0.005 (p<0.05)Keywords: Accuracy, Coding, Acute Bronchitis.
THE EFFECT OF PROBLEM BASED LEARNING MODEL IN 2013 CURRICULUM ON LEARNING OUTCOMES AND SKILLS IN VOCATIONAL EDUCATION
Authors: Wagino Wagino , Jalinus Nizwardi , Abdullah Rijal , Ridwan Ridwan , Nanda Iffarial , Hariyadi Hariyadi
Published: April 2022

This study aims to determine the effect of the problem based learning model on learning outcomes and skills in Motorcycle Engineering courses for D3 Automotive Engineering students, Faculty of Engineering, Padang State University. The research method used is an experiment with a modified pretest-posttest group research design. The sampling technique used is cluster random sampling, with Group 1 as the experimental class and Group 2 as the control class. The analytical technique used is the average difference test, analysis of the influence between variables, and determination of the coefficient of determination. The results of the study obtained that the average learning outcomes and motorcycle engineering skills in the experimental class was 89.56 while the control class was 81.54. The analysis of the influence between variables resulted in a biserial coefficient of 0.59 for learning outcomes and 0.44 for Motorcycle Engineering skills. The calculation of the coefficient of determination shows that the application of the problem based learning model contributes 35.00% to learning outcomes and 19.34% to Motorcycle Engineering skills. The relationship between Motorcycle Engineering skills and learning outcomes in problem based learning model learning is 31.69%. Based on the results of the study, it can be concluded that the application of the problem based learning model affects the learning outcomes and skills of Motorcycle Engineering students of D3 Automotive Engineering, Faculty of Engineering, Padang State University on CVT Maintenance material.Keywords: learning outcomes, Motorcycle Engineering skills, problem based learning
Zika Virus Infection and Pathogenesis
Authors: Theberge Karli , Derby Sarah , Ramirez Emily , May Meghan
Published: April 2022

Zika virus (ZIKV) is a flavivirus that was met with relatively little acclaim when it was discovered in 1947. Initial clinical reports of ZIKV included asymptomatic infection or mild, febrile illness; however, the view of ZIKV as an insignificant virus changed dramatically following the epidemic in the Western Hemisphere that started in 2015. This epidemic featured central nervous system involvement in children and adults, and a devastating congenital syndrome following infection of pregnant women. While the pathogenicity of ZIKV was virtually undescribed prior to this epidemic, in the past few years, numerous reports have described receptor–ligand interactions, aspects of tissue tropism, host–pathogen interactions, and diversity across viral clades. In this paper, the variety of clinical presentations and virulence determinants of ZIKV are reviewed.
Patent Activity of the Region as a Driver of Development of the Russian Economy
Authors: Ilina Irina , Zolotykh Natalya , Bitkina Inna
Published: April 2022

Introduction. Objects of Intellectual property bring significant finan­cial benefits to their owners through the sale of rights to this type of property and the conclusion of licencing contracts. At the same time, they play a big role in sustainable development of economy of regions as well. Creation of an active market of objects of intellectual property will allow the regions to reach a new level of development, character­ised by the emergence of IP-intensive industries that allow ensuring not only the growth of GRP, but also the level and quality of life of residents. However, this will require regional authorities to build an ef­fective intellectual property management system. Assessment of the region's achievements in the development of the regional intellectu­al property market will allow both identifying leaders and analysing their experience, and forming recommendations for outsider regions. To form such rating, it is proposed to calculate the index of patent activity of regions. Methods. The choice of the method for calculating the index is based on analytical studies of the methodologies for com­piling ratings of regions based on aggregate indices. Induction method was used for selection of indicators. The systematic method allowed determining the influence of intellectual property on the obtained so­cio-economic effects. Results and Discussion. Based on the assess­ment of the constituent entities of the Russian Federation in terms of the indicators characterising their patent activity, indicators were formed that served as the basis for calculating the index, upon which the rating of the constituent entities of the Russian Federation will be built. The key tasks are to assess the conditions created in the region, which contribute to the growth of the number of companies with a high share of intangible assets, including in sectors of strategic importance for the development of the region. Conclusion. A system for assessing the patent activity of a constituent entity of the Russian Federation is proposed, on the basis of the results of which it is possible to formulate decisions on state regulation and the implementation of measures to support the creation and introduction into economic circulation of the results of intellectual activity.
Analysis of the Principles, Models and Mechanisms of Financing of University Science in Russia
Authors: Krasnova Gulnara
Published: April 2022

Introduction. The development of university science is one of the pri­orities of the state scientific and technical policy, as evidenced by the increase in funding and organisational and legal changes in the func­tioning in this field. The Decree of the President of the Russian Federa­tion "On the National Development Goals of the Russian Federation for the Period up to 2030" dated July 21, 2020, sets the goal of "ensuring the presence of the Russian Federation among the 10 leading coun­tries in the world in terms of the volume of research and development, including through the creation of an effective system of higher educa­tion". In this regard, according to the authors of the article, it is relevant to study the existing principles, models and mechanisms of financing of university science, as well as an assessment of the current amount of funding for research in universities by the main sources and mech­anisms of financing on the basis of available statistics. Methods. The methods of statistical data analysis, comparison and generalisation of the obtained results, methods of comparative analysis of socio-eco­nomic information, international methodology of calculation of so­cio-economic indicators, agreed by the OECD, UNESCO and Eurostat were used in the paper. Results and Discussion. The contribution of university science to the scientific complex of the country remains in­ significant. The peculiarities of the Russian sector of higher education are the predominance of basic funding over competitive funding, as well as the priority of funding of "academic science" over higher edu­cation. In general, the extensive growth of university science in recent decades is mainly associated with state support. At the same time, this growth is uneven due to the concentration of this support on a small group of leading universities, especially federal, research and reference universities. Conclusion. According to the authors, the achievement of the national goal of ensuring the presence of Russia among the 10 leading countries in the world in research and development by 2030 will require a review of the approach to funding scientific research of universities of different profiles in Russia.
Rospatent in the Management of Regional Development in the Development Paradigm of the Intellectual Property Area
Authors: Zubov Yury , Neretin Oleg
Published: April 2022

Introduction. There is a regional policy focus on the IP management due to the increasing role in global value chains and the competitive environment for regional goods and services. The development of a re­gional intellectual property market is particularly important in the face of sanctions challenges. The Federal Service for Intellectual Property works with the regions of the Russian Federation in various areas, the main of which are cooperation within the creation of Technology and Innovation Support Centres and the implementation of tripartite agreements. Methods. Methods of patent analysis, analysis of norma­tive regulations in the field of state regulation and support of innova­tive entrepreneurship and inventors in regions were used. Results and Discussion. Rospatent and the Ministry of Economic Development of Russia determined the composition of indicators that should be considered in the forecast values of the development of the IP area. In 2021, all planned values that assess the effectiveness of the imple­mentation of agreements were achieved. In 2021, Federal Institute for Industrial Property (FIPS) specialists developed Methodological Recommendations for the regions on the formation of a strategic vi­sion and the definition of target indicators for the development of the IP area and Methodological Recommendations for the regions on the construction of an IP management system. Rospatent accumulates and analyzes information on the creation of its own IP management sys­tems in the regions, including mechanisms of state support for innova­tive entrepreneurship and inventors. Conclusion. The challenges faced by the Russian economy directly affect the area of intellectual property. Currently, projects are actively implemented under the Business Climate Transformation Action Plan "Intellectual Property", including the crea­tion of the necessary tax conditions. In 2021, 15 customer-centric servic­es for the provision of public services based on modern domestic digital technologies were created. They are now being tested and will soon be put into operation.
Molecular Characteristics of m6A Regulators and Tumor Microenvironment Infiltration in Soft Tissue Sarcoma: A Gene-Based Study
Authors: Xiao Kang-Wen , Yang Zhi-Qiang , Yan Xin , Liu Zhi-Bo , Yang Min , Guo Liang-Yu , Cai Lin
Published: April 2022

Background: N6-methyladenosine (m6A) methylation played a key role in tumor growth. However, the relationship between m6A and soft tissue sarcoma (STS) was still unclear.

Methods: The characterization and patterns of m6A modification in STS (TCGA-SARC and GSE17674) were analyzed comprehensively through bioinformatics and real-time polymerase chain reaction (RT-PCR). The effects of different m6A modification patterns on prognosis and immune infiltration of STS were further explored. Differentially expressed gene (DEG) analysis was performed. Moreover, an m6Ascore was constructed by principal component analysis (PCA). In addition, two immunotherapy datasets (IMvigor210 and GSE78220) and a sarcoma dataset (GSE17618) were used to evaluate the m6Ascore.

Results: Huge differences were found in somatic mutation, CNV, and expression of 25 m6A regulators in STS. Two modification patterns (A and B) in STS were further identified and the m6A cluster A showed a better clinical outcome with a lower immune/stromal score compared with the m6A cluster B (p < 0.050).In addition to , most STS samples from m6A cluster A showed a high m6Ascore, which was related to mismatch repair and a better prognosis of STS (p < 0.001). In contrast, the m6A cluster B, characterized by a low m6Ascore, was related to the MYC signaling pathway, which led to a poor prognosis of STS. A high m6Ascore also contributed to a better outcome of PD-1/PD-L1 blockade immunotherapy.

Conclusion: The modification patterns of 25 m6A regulators in the STS microenvironment were explored comprehensively. The novel m6Ascore effectively predicted the characteristics of the tumor microenvironment (TME) and outcome in STS and provided novel insights for future immunotherapy.
The Potential of Eukaryotic Cell-Free Systems as a Rapid Response to Novel Zoonotic Pathogens: Analysis of SARS-CoV-2 Viral Proteins
Authors: Ramm Franziska , Dondapati Srujan K. , Trinh Hoai Anh , Wenzel Dana , Walter Ruben M. , Zemella Anne , Kubick Stefan
Published: April 2022

The ongoing pandemic caused by the novel coronavirus (SARS-CoV-2) has led to more than 445 million infections and the underlying disease, COVID-19, resulted in more than 6 million deaths worldwide. The scientific world is already predicting future zoonotic diseases. Hence, rapid response systems are needed to tackle future epidemics and pandemics. Here, we present the use of eukaryotic cell-free systems for the rapid response to novel zoonotic diseases represented by SARS-CoV-2. Non-structural, structural and accessory proteins encoded by SARS-CoV-2 were synthesized by cell-free protein synthesis in a fast and efficient manner. The inhibitory effect of the non-structural protein 1 on protein synthesis could be shown in vitro. Structural proteins were quantitatively detected by commercial antibodies, therefore facilitating cell-free systems for the validation of available antibodies. The cytotoxic envelope protein was characterized in electrophysiological planar lipid bilayer measurements. Hence, our study demonstrates the potential of eukaryotic cell-free systems as a rapid response mechanism for the synthesis, functional characterization and antibody validation against a viral pathogen.