bluuebunny/crossref_metadata_2025 huggingface dataset:
The Induce Damage to Liver and Kidney of Wistar Rat by Spent Vegetable Oil and the Ameliorating Potentials of Coconut Oil
Authors: SIMON ISTIFANUS ADAMUN , SOLOMON MARIAM DANLADI , SANGODARE ROSE S.A. , DABAK JONATHAN D. , ABUBAKR ABDULLAHI
Published: October 2023

It has been a regular practice in this part of the world to continually use spent edible oil and consumed it without knowing the harmful effects of such. Heating results in the formation of free reactive oxygen species (ROS) which is responsible for oxidative stress and changes to various organs in the body. The study aimed at investigating the changes caused on liver and kidney by consumption of repeatedly used (spent) oil and possible ameliorating potential of virgin coconut oil (VCO) on spent vegetable oil-induced liver and kidney changes in Wistar albino rats. Blood samples were obtained and assayed for biomarkers of liver and kidney damage; Liver and kidney were harvested to study the histological changes before, during and after administration of virgin coconut oil. It was observed that spent vegetable oils induced severe damage on liver and kidney. While administration of virgin coconut oil significantly (p < 0.05) reversed the changes induced by the spent oil as observed in the biomarkers AST, ALT, ALP, Urea, Creatinine, Uric acid, Total serum protein, Albumin. These findings suggest that VCO could ameliorate the adverse effect of consumption of spent oil on liver and kidney indices in rats.
The Synergistic effect of nanoclay/nanosilica on mechanical properties and swelling resistance of ternary rubber (NR/SBR/NBR) blends nanocomposites
Authors: Srin J. , Jagatheeshwaran M. S. , Vishvanathperumal S. , Prabhu K. A. V. Roossvelt
Published: October 2023

In this research, we delve into the influence of hybrid filler loading, comprising both nanoclay and nanosilica (NC/NS), on the mechanical properties and resistance to swelling in ternary rubber nanocomposites composed of natural rubber (NR), styrene-butadiene rubber (SBR), and nitrile butadiene rubber (NBR). In this investigation, the composition of NR/SBR/NBR was kept constant at 30/30/40 phr, while the nanoclay was maintained at 6 phr and the proportion of nanosilica was varied from 0 to 6 phr. The nanocomposites were meticulously prepared through a melt mixing technique. Subsequently, we conducted an exhaustive assessment of their mechanical properties, encompassing parameters such as tensile strength, stress at 100% elongation (M100), elongation at break (EB), tear strength, compression set, hardness, rebound resilience, and abrasion resistance. Our findings reveal a discernible trend: as the nanosilica loading increased in the presence of the SCA, several key characteristics exhibited significant improvements. Specifically, the minimum torque, maximum torque, cure rate index, tensile strength, M100, tear strength, compression set, hardness, and crosslink density all showcased notable increases. In contrast, scorch time, cure time, EB %, and mole percent uptake (MPU) demonstrated a consistent decrease.
Trimetazidine Attenuates Ischemia/Reperfusion-Induced Myocardial Ferroptosis by Modulating the Sirt3/Nrf2-GSH System and Reducing Mitochondrial Oxidative Stress
Authors: Tan Mingyue , Yin Yunfei , Chen Weixiang , Jin Yifeng , Zhang Jun , Zhang Yue , Zhang Lei , Jiang Tingbo , Jiang Bin , Li Hongxia
Published: October 2023

Background and Purpose：
Ferroptosis is a newly defined mode of cellular demise. Increasing investigatieon supports the hypothesis that ferroptosis is a crucial factor in the complex mechanisms of myocardial ischemia-reperfusion(I/R) injury. Hence, the pursuit of ferroptosis as a therapeutic approach has promise in the management of myocardial damage. Although evidence suggests that trimetazidine (TMZ) is potentially efficacious against myocardial injury, the exact mechanism of this efficacy is yet to be fully elucidated. The objective of this work is to determine whether TMZ can act as a ferroptosis resistor and affect I/R-mediated myocardial injury.
Methods：
We constructed in vitro and in vivo models of I/R using H9C2 cardiomyocytes, primary cardiomyocytes, and SD rats. The optimal concentration of TMZ was determined by CCK8 and LDH experiments. Ferroptosis was confirmed by detecting the levels of GSH, lipid peroxidation ,and Fe2+, and the morphological alterations of mitochondria under transmission electron microscopy. Western blotting, RT-qPCR, and immunofluorescence staining were performed to detect the expression of iron death-related markers, including GPX4, SLC7A11, ACSL4, TFRC, and FTH. The Sirt3/Nrf2 pathway, which is associated with ferroptosis, was detected by Western blotting. We investigated the effects of Sirt3 molecules on TMZ-mediated inhibition of ferroptosis and cardioprotection by interfering with Sirt3 expression or activity using si-Sirt3 or 3-TYP (inhibitor of Sirt3 activity).
Results:
I/R mediated the onset of myocardial ferroptosis in vitro and in vivo, as reflected by excessive iron aggregation, GSH depletion, and the increase in lipid peroxidation. TMZ largely reversed this alteration and attenuated myocardium injury. Mechanistically, TMZ upregulated the expression of Sirt3. The use of si-Sirt3 and 3-TYP partly mitigated the inhibitory effect of TMZ on I/R-mediated ferroptosis and upregulated the expression of Nrf2 and its downstream target, GPX4-SLC7A11.
Conclusions:
TMZ attenuates I/R-mediated ferroptosis by activating the Sirt3-Nrf2/GPX4/SLC7A11 signaling pathway.
Detailed studies of 12C structure and reactions
Authors: Fortunato Lorenzo
Published: October 2023

We are reporting here on a series of theoretical investigations with both algebraic models and geometric cluster models of 2+ state with the purpose, in particular, of establishing if the rotational bands are compatible with rigid structures or rather if they are quantum mixture of different configurations.In a first series of paper [1, 2], we assume a rigid equilateral triangle shape and study in detail several properties that descend from the algebraic framework, such as the energy spectrum, electromagnetic observables and calculate the transition densities in order to extract elastic and inelastic cross-sections for various processes.In a second series of papers [3, 4], with correlated Gaussian basis functions. The two-body density distributions indicate that the main configurations of both the 0+2 and 2+2 states are acute iscosceles triangle shapes coming from 8Be(0+)+α configurations and find some hints that the second 2+ state is not an ideal rigid rotational band member of the Hoyle state band.
Comparative Analysis of Urban Greening Design Scenarios on Microclimate and Thermal Comfort
Authors: Teshnehdel Saeid
Published: October 2023

According to population growth, urban sprawl, as well as global warming, attention to the impact of design on thermal comfort in open spaces is important. Thus, it is essential to climate studies and understanding environmental features, as well as results usage in improving designs. The aim of this research is to use optimal climate knowledge to improve the quality of urban spaces; so with suitable use of natural resources can be achieved in a sustainable urban environment and responsive to the needs of human. With regard to the simulation and analysis by ENVI-met software, the result of this paper showed that, by choosing the suitable species and number of trees on outdoor, Ta and the MRT in the summer were reduced by 0.29 ˚C and 20.04 ˚C respectively and the RH increased by 3.51%. Overall, PET improved from 34.92 to 26.16 ˚C and PMV decreased from 2.31 to 0.86 in the summer which means that they are reached around comfort zones.
Bronchoalveolar Lavage Fluid Cytology of Deployed Military Personnel with Chronic Respiratory Symptoms from the STAMPEDE III Study
Authors: Boster Joshua , Moore William , Anderson Jess , Gonzales Michael , Houle Mateo , Walter Robert , Morris Michael
Published: October 2023

Background:Deployed military personnel may be at risk for developing acute and chronic lung disease. Prior studies of this patient population have revealed that unexplained exertional dyspnea is the most common diagnosis despite an extensive evaluation. There is concern that an occult disorder may be affecting this population. This study evaluated the role for bronchoalveolar lavage (BAL) fluid analysis in the evaluation of chronic deployment associated dyspnea.
Methods: Military personnel who reported chronic respiratory symptoms were evaluated as part of the STAMPEDE III study. Participants underwent bronchoscopy with BAL as part of a standardized evaluation.
Results: 308 patients with a mean age of 38 ± 8.6 years underwent bronchoscopy with BAL. BAL cell count percentages of macrophages, lymphocytes, neutrophils, and eosinophils respectively were: 76.2 ± 17.0%, 16.3 ± 13.4%, 6.6 ± 8.9%, and 0.9 ± 3.2%. There was no clear differentiation between groups based on increases in lymphocyte counts (p = 0.640) although lymphocyte values were more elevated (21.4 ± 12.1%) in the interstitial lung disease category. Neutrophil counts (6.6 ± 8.9%) were elevated compared to the reported normal reference values and were increased in the isolated pulmonary function test (PFT) abnormality (9.4 ± 11.6%), large airway disorder (10.0 ± 7.5%), miscellaneous (10.9 ± 20.2%), and obstructive lung disease (11.0 ± 15.6%) groups. Eosinophil counts were within normal limits (0.9 ± 3.2%) and showed no differences between groups (p = 0.545); asthma patients trended higher (1.6 ± 5.7%). BAL counts for the exertional dyspnea group were within normal reference values and showed no differences from the entire cohort.
Conclusion:The addition of BAL cytology did not help differentiate those patients with unexplained dyspnea from other etiologies.
Transfer Entropy and Granger Causality in Real-world Telecommunication Networks
Authors: Polaganga Roopesh Kumar , Liang Qilian
Published: October 2023

Telecommunication networks are highly intricate, with numerous interacting components influenced by various known and unknown factors. Among these, Radio Access Networks (RANs) play a critical role in wireless communication. Unraveling causal relationships within such complex systems is essential for their improvement and optimization through statistical and data analysis techniques. This study pioneers the application of Transfer Entropy (TE) and Granger Causality (GC) to real-world telecommunication networks, marking the first exploration of these methods in this context. We assess their effectiveness in identifying relationships among key network attributes, offering insights for potential system optimization in practical scenarios. Furthermore, our research extends to a comparative analysis of TE and GC under varying network load conditions, utilizing live data collected from multiple base stations to uncover common patterns across identified network attributes.
The association between dietary patterns and metabolic syndrome among Iranian adults, a cross-sectional population-based study (findings from Bandare-Kong Non-Communicable Disease Cohort Study)
Authors: Kheirandish Masoumeh , Dastsouz Farideh , Azarbad Abnoos , Mohsenpour Mohammad Ali , Javedan Gholamali , Razmpour Farkhondeh , Davoodi Seyed Hossein , Ramezani-Jolfaie Nahid , Mohammadi Mohammad
Published: October 2023

Background
Metabolic syndrome is a cluster of metabolic disorders increasing the risk of cardiovascular disease and diabetes. Dietary patterns are supposed to be important and controllable factors in developing metabolic syndrome. The purpose of this study was to investigate the association of dietary patterns with metabolic syndrome and its components.
Subjects/Methods:
Cross-sectional data were extracted from the Bandare-Kong cohort study conducted in people aged 35 to 70. Dietary patterns were extracted using principal component analysis based on thirty-eight pre-defined food groups. Multivariable logistic regression was conducted to investigate the association between metabolic syndrome and its components with quintiles of dietary patterns in crude and adjusted models.
Results
Three major dietary patterns were identified (healthy, western, and traditional). After adjusting for covariates, the chance of metabolic syndrome was significantly decreased by 46% in the highest quintile of the healthy pattern compared to the lowest quintile. However, in fully adjusted models, no significant association between western and traditional dietary patterns was observed with the chance of metabolic syndrome. On the other hand, the fully adjusted model showed an inverse association between higher adherence to healthy dietary patterns and the chance of increased blood glucose, high waist circumference, and elevated blood pressure. The odds of abnormal levels of metabolic syndrome components were not significantly different in quintiles of the western and traditional dietary patterns.
Conclusions
Following a healthy dietary pattern, including fruits, vegetables, nuts, low-fat dairy products, and legumes, can help prevent and control metabolic syndrome.
The effect of Norethisterone Acetate (NETA) on the uterus of albino rats: Histological, histochemical, immunohistochemical and ultrastructure Study
Authors: Abd-Elkareem Mahmoud , Alnasser Sulaiman Mohammed , Meshal Alotaibi , Abdullah Raghda Ismail , Ali Ahmed U.
Published: October 2023

Norethisterone acetate (NETA), also known as norethindrone acetate is a progestogens medication that is widely used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders as abnormal uterine bleeding and endometriosis. There is a lack of detailed histological information regarding the effects of NETA on the uterine structure. So, the present study focuses on the uterine histological, histochemical and ultrastructure sequelae following the exposure to NETA in the albino rats. To do this aim, fourteen adult female albino rats were used. They were randomly divided into two equally groups: Control group and NETA treated group. Albino rats of control group were administered daily food, water and orally distilled water only, while rats of NETA treated group were administered daily orally 20 µg of NETA dissolved in 2 ml distilled water, food, and water. The experiment was continued for three weeks. The findings of the present work indicated that the use of NETA has negative effects on the endometrial epithelium (proliferation, autophagy and apoptosis), glands (necrotic, apoptotic or pseudosecretory glands) and stromal and myometrial reactions (granulocytes, connective tissue remodeling, apoptosis, myocytes hypertrophy). This work revealed that NETA has desynchronized progestogenic effect on the uterine tissues of the albino rat and thereby prevent implantation and pregnancy.
Precision reduction of femoral neck fractures: A novel strategy based on the femoral neck fracture morphology
Authors: Lin Dongze , Peisheng Chen , Chaohui Lin , Lin Fengfei
Published: October 2023

Background
In femoral neck fractures the secondary damage caused by repeated multiple reductions needs to be prevented. Accordingly, the aim of this study was to achieve an anatomical reduction in the first manipulation of reduction in femoral neck fractures. We propose a new reduction strategy using the x-ray morphology of femoral neck fractures for preoperative planning. In the present study we compared this approach to conventional operation procedures for the treatment of femoral neck fractures.
Method
From 2020 to 2021, 35 patients with femoral neck fractures were operated with this reduction strategy. Those were compared with 34 patients treated without the proposed preoperative method. All patients were compared for consistency between the preoperative assessment and the intraoperative execution of the reduction approach, number of reductions, operative time, number of fluoroscopies, intraoperative bleeding, and reduction quality.
Results
The operative time of patients in the study group was significantly shorter (38.40±10.26 min) than that of the control group (47.26±9.09 min), and the number of reductions [1.0 (1.0,1.0)] was significantly less than that of the control group [2.0 (1.75,2.25)]. The number of fluoroscopies (10.27±2.84) was also significantly less than that of the control group (13.53±2.59) times. The KAPPA value = 0.886 shows the good agreement between the preoperative proposed protocol and the intraoperative protocol about the study group .The bleeding, quality of repositioning, Harris Hip score, MOS 12-item Short Form Survey (SF-12), and early complication rate were not statistically different between the groups (P > 0.05).
Conclusion
The selection of the appropriate repositioning method based on the analysis of femoral neck fracture X-ray morphology can improve the efficiency and accuracy of preoperative planning. This reduces the secondary damage that may be caused by multiple reduction, shortens the operation time and reduces the exposure to radiation.
An overall study on flavor characterization of Citrus Puerh tea based on GC-MS-O and untargeted metabolomics
Authors: Sun Jiaqing , Cai Weitong , Feng Tao , Chen Da , Lu Jun , Song Shiqing , Yao Lingyun , Sun Min , Wang Huatian , Liu Qian , Yu Chuang
Published: October 2023

Chinese Citrus Pu-erh tea is recognized for its unique flavor, which is composed of key aroma-active compounds and affected by taste-impact metabolites. In this study, the whole citrus Pu-erh tea (CP), its out-layer fruit (OF) container and inside tea (IT) powder, were analyzed by solvent-assisted flavor evaporation (SAFE) coupled with GC-MS-O and UHPLC-MS/MS. As the result, 47 important volatiles were identified, including 27 (IT), 30 (OF) and 27 (CP) volatiles that were screened out based on their OAV (odor activity value) and ACI (aroma character impact value), and further validated by aroma omission/recombination experiment. Combined with the sensory evaluation and PLSR model, the aroma profile of CP was characterized with the following ten flavor attributes: sweet (vanillin); floral (β-ionone); fruity (methyl anthranilate, methyl methanthranilate, citronellal); roasted (thymol); musty (p-cymene), woody (perillaldehyde); herbal (linalool, α-terpineol); phenolic (2,4-di-tert-butylphenol, p-cresol); minty (dihydrocarvone); and fatty (octanoic acid) volatiles. As for the non-volatile taste-impact chemicals, the most prominent metabolites were identified as flavonoids that mainly contributed to the taste of bitter (catechin, epicatechin, gallocatechin), astringency (leucopelargonidin) and sweet (neohesperidin). This novel finding has provided an insight and better understanding of the flavor profile of Citrus Pu-erh tea and some guidance for flavor pairing and taste improvement.
Effect of 40hz Light Flicker on Cognitive Impairment and Transcriptome of Hippocampus in Right Unilateral Common Carotid Artery Occlusion Mice
Authors: Niu Zhaorui , Yu Minjie , Xu Peixia , Liu Renchuan , Li Shangda , Wu Congchong , Huang Bochao , Ye Xinyi , Hu Jianbo , Xu Yi , Lu Shaojia
Published: October 2023

Vascular cognitive impairment caused by chronic cerebral hypoperfusion (CCH) seriously affects the living quality in elderly patients. However, there has been no effective treatment to control this disease. This study investigated the potential neuroprotective effect of the 40hz light flicker in a mouse model of CCH. CCH was induced in male C57 mice by right unilateral common carotid artery occlusion (rUCCAO), leading to chronic brain injury. The mice underwent 40hz light flicker stimulation for 30 days after surgery. The results showed that 40hz light flicker treatment ameliorated the memory deficits after rUCCAO and alleviated the damage to neurons in the frontal lobe and hippocampus. Light flicker administration at 40hz decreased IL-1β and TNF-α levels in the frontal lobe and hippocampus, although immunohistochemistry found that it did not exert angiogenesis in mice with rUCCAO. Gene expression profiling revealed that the induction of genes was mainly enriched in inflammatory-related pathways. Our findings demonstrate that 40hz light flicker can suppress cognitive impairment caused by rUCCAO and that this effect is may be invovled in the attenuation of neuroinflammation.
Analysis of clinical characteristics and factors affecting treatment responses in patients with pyoderma gangrenosum: A multicenter study of 239 patients
Authors: Erduran Funda , Adışen Esra , Hayran Yıldız , Aksoy Güneş Gür , Alpsoy Erkan , Selçuk Leyla Baykal , Doğan Sibel , Yazıcı Ayça Cordan , Öktem Ayşe , Güngör Malik , Afacan Elif , Kuşçu Deniz Devrim , Elmas Leyla , Aydoğan Kübra , Bayramgürler Dilek , Demirsoy Evren Odyakmaz , Akyol Melih , Yasak Rukiye , Erdoğan Hilal Kaya , Acer Ersoy , Ergun Tulin , Yaylı Savaş , Bulut Ferhan , Saraç Esra , Aktaş Akın
Published: October 2023

Pyoderma gangrenosum (PG) is a chronic disease characterized by recalcitrant skin ulcers. We aimed to evaluate retrospectively the demographic, clinical characteristics, treatment data and factors affecting treatment responses of patients followed up with diagnosis of PG in 12 tertiary care centers from 8 different provinces in Turkey between the years 2012–2022. We included a total of 239 patients of whom 143 (59.8%) were female and 96 (40.2%) were male, with an average age of 54.2 ± 17.4 years. At least one comorbidity associated with PG was found in 51.5% of our patients. The most common comorbidities were inflammatory arthritis (18.8%) and inflammatory bowel disease (IBD) (15.9%). The most common treatment was systemic steroids (75.7%). Among these patients 50.8% used systemic steroids as the sole systemic agent, while 49.2% used at least one adjuvant immunosuppressive agent. The general characteristics of our patients who responded well to systemic steroid treatment were those with a late onset of disease, shorter disease duration, fewer lesions, single region involvement, negative wound culture results, negative pathergy, and those without inflammatory arthritis and IBD (all p < 0.05). Biological agents were used in 18.4% of our patients in our study. The general characteristics of the patients who switched to biologics as a second or third line treatment are those with early disease onset, younger patients, males, those with autoinflammatory diseases, those with IBD and hidradenitis suppurativa and pathergy positive ones (all p < 0.05). Our study had compelling data concerning two specific patient groups: Pathergy positivite and early onset (onset age < 30) PG groups. We think that investigation for accompanying autoinflammatory diseases at the time of diagnosis in these two groups is necessary and the patients in these two groups are more resistant to treatment, necessitating more complicated treatments. We believe that the results of our multicenter study will contribute to the literature.
Bond Strength of Thermally Aged CAD/CAM Hybrid Nanoceramic Repaired with Nanohybrid Resin Composite
Authors: AbouShahba Mostafa , Younis Sara H.
Published: October 2023

Purpose. To assess shear bond strength (SBS) of nanohybrid resin composite used to repair CAD/CAM Hybrid Nanoceramic ceramic after various surface treatments.
Materials and Methods. SHOFU HC Hybrid Ceramic disks were sliced to obtain circular-shaped specimens (n= 30). All specimens were thermocycled (5000 thermal cycles), then divided into three groups according to surface treatment performed (sandblasting, HF acid etching, and laser irradiation) (n = 10). Repair with nanohybrid resin composite was performed. SBS values were obtained, and failure modes were determined. Data were statistically analyzed (P ≤ 0.05).
Results. The highest SBS mean value was found with (Sandblasting), while the lowest mean value was found with (Laser). There was a statistically significant difference between (Sandblasting), (Hydrofluoric acid) and (Laser) groups where (p=0.001). Statistically significant difference was found between (Sandblasting) and each of (Hydrofluoric acid) and (Laser) groups where (p=0.003) and (p=0.001) respectively, while no statistically significant difference was found between (Hydrofluoric acid) and (Laser) groups where (p=0.291).
Conclusion. Surface treatment of the CAD/CAM hybrid nanoceramic material surface with sandblasting before repairing is mandatory to enhance the bond strength with nanohybrid resin composite repairing material. HF acid etching and laser irradiation are alternative surface treatment methods for CAD/CAM hybrid nanoceramic materials.
Masked Facial Recognition System using Multi-Branch Deep Learning Models and Splatted Dataset.
Authors: Fahim Mahmoud , Abdel-Nasser Mohamed , Abdelwahab Moataz , Abdel-Rahman Adel B.
Published: October 2023

In the last decade, face recognition (FR) has gained more importance in applications like security, access control, …etc. The FR performance gets closer to the human performance. But the spread of Covid-19 disease returns it some steps behind. The fear of covid-19 dangerousness forced people to wear medical masks. Wearing a mask increased the difficulty by losing half of the data behind the mask. In this paper, we propose a small identification system containing two parts. The first part, the detection part, takes the image from a video frame or image, and it detects the face/s using MTCNN detection. The second part, the decision part, used the output face/s from the first part and splits the face into lower and upper partitions. The lower partition enters the masked/unmasked CNN model. The upper partition is input to identify the person CNN model. We describe three proposed models with an accuracy of 93%, 99.88%, and 100%. Our strategy for dealing with the dataset is to divide the dataset into small datasets, each containing only fifty classes at most. So that several models are trained on small datasets, and each model is trained on small datasets different from those used for training in the other model, instead of training one model on the primary dataset. This strategy helped to increase accuracy and reduce error, execution time, and training time than required to train a single model on the main dataset.
A system for the study of roots 3D kinematics in hydroponic culture: a study on the oscillatory features of root tip
Authors: Simonetti Valentina , Ravazzolo Laura , Bulgheroni Maria , Ruperti Benedetto , Quaggiotti Silvia , Castiello Umberto
Published: October 2023

Background
The root of a plant is a fundamental organ for the multisensory perception of the environment. Investigating root growth dynamics as a mean of their interaction with the environment is of key importance for improving knowledge in plant behaviour, plant biology and agriculture. To date, it is difficult to study roots movements from a dynamic perspective given that available technologies for root imaging focus mostly on static characterizations, lacking of temporal and three-dimensional (3D) spatial information. This paper describes a new system based on timelapse for the 3D reconstruction and analysis of roots growing in hydroponics.
Results
The system is based on infrared stereo-cameras acquiring time-lapse images of the roots for 3D reconstruction. The acquisition protocol guarantees the root growth in complete dark while the upper part of the plant grows in normal light conditions. The system extracts the 3D trajectory of the root tip and a set of descriptive features in both the temporal and frequency domains. The system has been used on Zea mays L. (B73) during the first week of growth and shows good inter-reliability between operators with an Intra Class Correlation Coefficient (ICC) > 0.9 for all features extracted. It also showed measurement accuracy with a median difference of < 1 mm between computed and manually measured root length.
Conclusions
The system and the protocol presented in this study enable accurate 3D analysis of primary root growth in hydroponics. It can serve as a valuable tool for analyzing real-time root responses to environmental stimuli thus improving knowledge on the processes contributing to roots physiological and phenotypic plasticity.
How online celebrity live streaming promotes consumption? --- A theoretical and empirical test based on the Howard-Sheth model
Authors: Wu Chunya , Yang Jing , Ma Zhenhao
Published: October 2023

Online celebrity live streaming has thrived as one of the new consumption paradigms, consistently fostering a rebound in China's consumption and economic growth. This study empirically investigates whether and how online celebrity live streaming influences consumers' purchase behavior. To this end, we measured consumers' purchase behavior through purchase frequency and purchase amount, and our sample mainly included 617 consumers who had watched online celebrity live streaming and made product purchases, and we rely on the Howard-Sheth model to construct the theoretical framework. The results indicated that the substantive stimulus (product information and product quality) and symbolic stimulus (credibility, entertainment, and professionalism) of online celebrity live streaming had a significant promotion effect on consumers' purchase behavior. Even with the regression model and explained variables replaced, this conclusion was still solid. According to the results of the heterogeneity analysis of different product categories, the promotion effect of product information on the purchase frequency of clothing and apparel products was more obvious, the promotion effect of product quality on the purchase frequency of beauty and personal care products was more obvious; the promotion effect of entertainment on the purchase amount of beauty and personal care products was more obvious; the promotion effect of credibility and professionalism on the purchase frequency of leisure snack products were more obvious. The mechanism test demonstrated that online celebrity live streaming influenced consumers' purchase behavior through three paths: perceived functional value, perceived emotional value, and perceived risk.
TB patient delay, diagnosis delay, and treatment among migrants in Shanghai in 2018- 2020: a mixed-methods study
Authors: Jia Yufei , Jiang Weixi , Xiao Xiao , Lou Zhexun , Tang Shenglan , Chen Jing , Long Qian
Published: October 2023

Background
The relatively high TB incidence rate among internal migrants raises a major concern on TB control in China. This study examines TB patient delay, diagnosis delay, and treatment performance in Shanghai in 2018–2020 focusing on disparities between migrant and local TB patients.
Methods
This study employed mixed methods. We obtained TB register data in 2018–2020 from the TB information management system (TBIMS) in Shanghai to examine patient delay, diagnosis delay, and treatment completion by resident type. Qualitative interviews were conducted with TB administrators and community healthcare providers to understand factors associated with TB treatment for migrant and local patients.
Results
From 2018 to 2020, migrant TB patients accounted for 44.40% of total cases, with an average age of 34.50, compared to local patients averaging 55.82 years old. Overall, there was no significant difference in patient delay between migrant and local patients (18.47 days on average). 22.12% of migrants and 16.52% of locals experienced diagnosis delays exceeding 14 days, respectively. After adjusting for all variables, migrant patients (OR 1.30, 95%CI, 1.18–1.44) and initial care-seeking at general hospitals (OR 3.76, 95% CI 3.45–4.09) were associated with a higher probability of diagnosis delay. 93.9% of migrant patients and 89.4% of the local patients had a successful TB treatment without statistically significant difference after adjusting for all variables. Qualitative interviews revealed a standard approach to managing TB patients in Shanghai no matter their resident type. Young migrant patients who were able to maintain their jobs in Shanghai often had better treatment adherence. Despite more patients postponed seeking care due to fear of COVID-19 and inconvenient access to care in 2020, the COVID-19 epidemic had minimal impact on TB treatment for both groups attributed to community-based case management.
Conclusions
There were no significant differences in TB patient delay and treatment outcome by type of resident between 2018 and 2020 in Shanghai, but migrant patients were more likely to experience diagnosis delay. It should improve awareness and knowledge of TB among healthcare professionals at general hospitals to mitigate the risk of diagnosis delay.
Diagnostic utility of ultrasonography in the management of postoperative ascites and abdominal indwelling catheters following pancreaticoduodenectomy：retrospective cohort study
Authors: zhang lingyun , Zhang Suzhen , Yan Ye , Wei Xinhong , Li Feng , Li Guangbing , Yang Fenghui , Li Chunyou , Liu jun , Li jianzhi , Zhang Guoquan , Zhang Dawei
Published: October 2023

Background：To investigate the diagnostic utility of ultrasonography for postoperative ascites following pancreaticoduodenectomy and evaluate the clinical efficacy of ultrasound-guided abdominal catheter placement. Methods：A total of 309 hospitalized patients underwent postoperative pancreaticoduodenectomy, with 171 patients undergoing laparoscopic pancreaticoduodenectomy and 138 patients undergoing open pancreaticoduodenectomy, as assessed by ultrasonography. The abdominal cavity was examined for the presence of postoperative ascites. The site of postoperative ascites and the necessity for tube drainage were evaluated. In cases where an abdominal indwelling catheter was required, we observed the location of postoperative ascites, performed echocardiography, and analyzed the characteristics of drainage fluid. We conducted a comparative analysis of short-term postoperative outcomes between LPD and OPD, encompassing hospitalization duration, fever duration, presence or localization of postoperative ascites, number of abdominal indwelling catheters used, location of abdominal drainage fluid collection, and time until removal of postoperative catheter
Results：The LPD group exhibited a significantly lower incidence of ascites stays compared to the OPD group (39.2% vs. 59.3%, p=0.001) as determined by ultrasonography. The LPD group exhibited significantly shorter hospital stays compared to the OPD group (16 [13, 21] vs. 21 [17, 28] days; p<0.001). Additionally, they experienced a reduced duration of fever (1 [0, 3] vs. 3 [1, 5]; p<0.001), shorter time to postoperative catheterization (7 [5, 10] vs. 8 [6, 13]; p<0.001), fewer number of tubes required (0 [0, 1] vs. 1 [0, 1]; p<0.001), and decreased extubation time (7 [5,9] vs.9[5，12];p<0。001) in comparison with the OPD group. Correlations were observed between the two groups in terms of postoperative ascites, sound transmission of the ultrasound, the separation of postoperative ascites and the traits of drainage fluid. However, no significant differences were observed between the two groups in terms of postoperative ascites location, the state of postoperative ascites (free or limitation), ultrasonic sound transmission (good or poor), and the separation of postoperative ascites (no separation, less separation and more separation).
Conclusion：Postoperative ascites is a frequently encountered concurrent condition following pancreaticoduodenectomy. Ultrasonography enables the observation of various characteristics associated with postoperative ascites, such as its precise location, sound transmission properties, and presence of any internal separations. Furthermore, it facilitates timely guidance for accurate tube placement.
Radiological Evaluation of Mediastinal lymphadenopathy and Masses
Authors: Gorieh Feryal , khattab Khalid
Published: October 2023

Background: Mediastinal masses and nodes are considered frequent pathological lesions in most countries of the world, especially Syria, and because they cause clinical symptoms ranging from mild to severe, they are diagnosed qualitatively with simple radiography and computed tomography. This study aims to study the role of radiological, laboratory and clinical diagnostic methods in detecting Mediastinal nodes and masses for better placement a treatment plan to achieve optimal recovery.
Methods and Materials: From the archives of patients at Al-Mowasat University Hospital, cases of diagnosed mediastinal nodes and masses were monitored in the Radiology Division and the Thoracic Internal Medicine Division, and the cases were followed up and managed in the Thoracic Surgery Division in the hospital within the period extending from 3/19/2023 to 8/2/2023, with reference to the Division’s archives. Radiology available on the PAX network, and analysis of simple radiographs and CT scans.
Results: The study included 456 patients, 105 cases of intramediastinal masses, and 351 cases of lymph nodes. Most of the mediastinal masses were primary (23%), the percentage of lymph nodes was (77%), the percentage of anterior mediastinal masses was (62%), and the percentage of middle mediastinal masses was (25%). ), the percentage of posterior mediastinal masses (13%), the percentage of cases that enhance contrast material (52%), the percentage of cough (50%), stridor (13%), tracheal deviated (5%), and the percentage of inferior vena cava syndrome (3%) ), chest pain (30%), pleural effusion (20%), dysphagia (10%), Horner syndrome (3%), hoarseness, fever, and myalgia (3%), (4%), and (6%) on straight.
Conclusion: The radiological gold standard for evaluating and detecting mediastinal masses is CT before and after injection. Each mediastinal mass is studied by CT before and after injection.
Compressive Buttress Compared with Off-Axial Screw Fixation for Vertical Femoral Neck Fractures in Young Adults: A Prospective, Randomized Controlled Trial
Authors: Yin Bo-hao , Liu Chen-jun , Sherrier Matthew C. , Fan Zhi-Yuan , Song Sa , Luo Peng-bo , Sun Hui , Zhang Wei
Published: October 2023

Background: To compare the clinical outcomes of compressive buttress screw (CBS) fixation, a novel screw fixation strategy, to off-axial screw fixation (off-axial partial-threaded cannulated screw, OPTCS) for vertical femoral neck fractures (FNFs) in young adults.
Methods: 146 adults younger than 55 years old with high-energy Pauwels type III FNFs were randomized to receive CBS fixation or OPTCS fixation. Primary outcomes were complication rates, including fixation failure, fracture nonunion, and avascular necrosis of the femoral head (ANFH) at 24 months after treatment. Fixation loosening, femoral neck shortening and varus collapse, patient function and quality of life using the Harris hip score (HHS), and EuroQol-5 dimensional-5 levels (EQ-5D-5L) questionnaire (including EQ-5D-5L and EQ-VAS) were assessed as secondary outcomes at 24 months.
Results: CBS and OPTCS fixation groups were similar with regard to demographics at baseline. At 24 months, patients in the CBS fixation cohort had a significantly lower rate of fixation failure (10.5% vs. 25.0%, p=0.041) and fracture nonunion (1.8% vs. 18.3%, p=0.003) compared with patients who received OPTCS fixation. There was no difference in rate of ANFH (7.0% vs. 11.7%, p=0.389) between groups. Additionally, patients managed with CBS fixation showed significantly less fixation loosening (19.3% vs. 58.3%, p<0.001), less severe femoral neck shortening and varus collapse (10.5% vs. 25.0%, p=0.007), higher HHS (93 vs 83, p=0.001) and more excellent grade (68.4% vs. 36.7%, p=0.008), higher EQ-5D-5L (0.814 vs, 0.581, p<0.001) and EQ-VAS (85 vs. 80, p=0.002).
Conclusion: CBS screw fixation confers significantly lower complication rate in addition to higher functional and quality of life outcomes for young adults with high-energy FNF compared with OPTCS fixation.
Trial registration: This prospective, randomized controlled trial was approved by the institutional review board of our center, Ethics Committee of Shanghai sixth people's Hospital, and registered at www.chictr.org.cn (Approval Number: ChiCTR1900026283；Registered 29 September 2019 - Retrospectively registered, https://www.chictr.org.cn/showproj.html?proj=43164).
Dyskinesia-hyperpyrexia syndrome in Parkinson’s disease may benefit from GPi deep brain stimulation: a case report
Authors: Huang Shi-Shi , Ma Lu-Lu , Sheng Han-Song , Liu Rong-Pei , Zhu Shi-Guo , Chen Zhu-Ling , Xu Shan-Shan , Sheng Mei-Ling , Zhang Nu , Zhang Xiong , Wang Jian-Yong
Published: October 2023

Introduction:
Dyskinesia-hyperpyrexia syndrome (DHS) is a rare but life-threatening complication in Parkinson’s disease (PD). Its prevention and treatment are clinical challenges.
Case presentation:
We herein present a case of a female PD patient who experienced recurrent episodes of DHS and levodopa-induced dyskinesia. The complications were alleviated after bilateral globus pallidus internus (GPi) deep brain stimulation (DBS).
Conclusion
Our report provides evidence that GPi DBS may reduce the susceptibility to DHS. More evidences are warranted to validate this hypothesis.
Bringing Sustainable Development Goals into Classrooms: Digital Picture books as Resources for Education for Sustainable Development
Authors: Ropiudin Asep
Published: October 2023

Sustainable development issues rarely become a discussion in classroom settings. Teachers tend to have limited understanding and negative attitudes regarding sustainability issues. Moreover, teachers aware of the importance of sustainable development usually struggle to find resources to discuss topics in the classroom. Not only do sustainability issues seem to be simplified in the textbooks, but the interconnection between subjects regarding sustainable development issues is minimal. Picturebooks can greatly nurture students’ awareness of sustainable development issues. Picturebooks can nurture students’ self-awareness in educational settings and help them develop a positive self-identity. The study evaluates and analyzes possible open-accessed resources for teaching Sustainable Development Goals (SDGs) in the classroom. The analyzed resources are digital picturebooks provided by Room to Read at literacycloud.org website. The framework used for categorization is adopted from the 17 SDGs established by the United Nations in 2015. The findings show that the sustainable development themes are represented in the picturebooks under analysis to a reasonable extent. Among the 17 SDGs, the most frequent themes that appeared in the picturebooks are SDG 4, Quality Education (17%), SDG 5, Gender Equality (14%), SDG 15, Life on Land (14%), SDG 10, Reduced Inequalities (12%), and SDG 11 Sustainable Cities and Communities (10%). However, themes related to SDG 1, No Poverty, SDG 7, Affordable and Clean Energy, SDG 13 Climate Action, and SDG 17 Partnerships for the Goals are hardly found in the picturebooks. The study findings can become a recommendation for teachers to teach and promote awareness of sustainable development in the classroom.
Empowering Tuberculosis-Responsive Village Governments: an Action Research Approach
Authors: Alfirdaus Laila Kholid
Published: October 2023

Through Presidential Regulation No. 67/2021 on Tuberculosis Control, the Government of Indonesia has announced the urgency of an integrative approach to handling TBC diseases, including at the village level. Nonetheless, there are still bottlenecks in the implementation as not all stakeholders know their tasks and responsibility. To this day, TBC has been a domain of the Ministry of Health. It is decentralized up to provincial, regency, and sub-district levels through Community Health Services (Pusat Kesehatan Masyarakat or Puskesmas). In fact, inadequacy can still be found in policy strategies—resulting in the TBC bearers being undetected, unreported, and unthreatened, which leads to persistently high TBC cases, including at the village level. Thus, it becomes necessary to push a broader role of village government considering their adjacency to society. The village government’s involvement in tracing, testing, and treatment strategy is necessary to facilitate community participation in TB prevention and control activities. This paper is based on action research focusing on strengthening village governance’s role in handling TBC prevention and control. Following a series of research to collect information regarding the needs and complexities of TB governance at the village level, the mission was followed with national-level advocacy. This was conducted to encourage further accommodating the village government’s role in contributing to TB prevention and control to the Ministry of Village, Disadvantaged Regions, and Transmigration. Despite its ongoing processes, this paper has identified strengths and weaknesses during the advocacy processes, which are expected to be considered in a future mission.
Application of Artificial Insemination (AI) Tool Based on Oestrus Automatic Detection to Improve Goat Pregnancy in Yogyakarta
Authors: Budiyanto Agung , Setyawan Erif Maha Nugraha , Datrianto Dwi Sunu , Nurcahya Dony , Pramono Budi
Published: October 2023

This study aims to determine the level of pregnancy in goats and sheep in Indonesia, especially in the Yogyakarta area, by comparing the use of conventional AI devices with AI devices equipped with endoscopes. Many factors, including livestock, breeders, officers, spermatozoa, and environmental factors, strongly influence reproductive performance. The process of pregnancy in goats and sheep begins with the process of estrus, mating, pregnancy, birth, and postpartum estrus as the beginning of a continuous cycle. The problem found that the pregnancy rate in goats and sheep is relatively low. The low genetic quality of goats and sheep causes population growth in Yogyakarta to run slowly. This research was conducted by direct observation of the animal’s condition, then observation using an AI smart endoscope. AI Smart endoscopy was used to observe estrus time and followed up with AI in goats that had shown AI time. Observation of pregnancy was carried out two months after AI. The results showed that AI using smart endoscopy AI Gun on 20 goats resulted in 55% pregnancy. This is higher than conventional AI, which is 35%. The success of AI using the estrus synchronization method is 65%. The benefit of this research is the achievement of increasing pregnancy and improving the genetic quality of goats and sheep by using an AI device equipped with an endoscope. The target of veterinarians and field paramedics is more accustomed to using modified AI devices to make it easier to detect estrus. This program is expected to increase both the number of fetuses from an average of only 1-2 to 2-3 births and the success rate of AI increases.
Assistance to Strengthen Micro, Small and Medium Enterprises (MSMEs) in Sanggrahan Village, Kranggan District,Temanggung Regency, Central Java
Authors: Hidayah Nurulia , Hardjo Karen Slamet , Baidlowi Ahmad , Lishianawati Tiara Uji
Published: October 2023

Sanggrahan Village, Kranggan District, Temanggung Regency, has potential in the field of natural resources. Therefore, good resource processing is needed through MSMEs to produce good products. The problem faced by MSMEs in the village is the lack of the community’s ability to manage the existing potential. The purpose of this program is to optimize natural resources through the development of the community’s capacity so that it helps overcome the problems that occur and can be applied sustainably in the future by the community. Service activities are carried out in the form of socialization and training involving the active participation of participants. This activity has shown some positive results, such as participants' understanding of product packaging, financial management, and the use of social media. Product innovation was also strengthened through training on processing cassava peel chips and catfish head rengginang. This program supports increasing village independence and follows the 4th, 8th, 9th and 17th Sustainable Development Goals (SDGs) through education-based community service for sustainable development.