bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Mass Media on Attitude and Practice of Public Health Knowledge among Urban Population of Bangladesh
Authors: Nowshin Iffat , Salim Farhana , Rozario Rini Juliet , Nazneen Humaira
Published: November 2022

This descriptive type of cross-sectional study was conducted among 180 persons of different socio-economic conditions of Dhaka city using semi-structured questionnaire through face-to-face interview to identify the impact of mass media in disseminating public health related messages to the urban population of Bangladesh. Convenience sampling was the process of selecting the subjects. Among 180 respondents mean age of the respondents was 28.75±8.55 years. Majority of the respondents were graduate (29.0%). Of the total 180 respondents 121 (67.2%) read newspaper and among them, 46 (38.32%) read Public Health related articles in the newspaper regularly. On the other hand out of the total 180 respondents 170 (95.0%) watch television and of them 36 (21.18%) watch public health related programme in the television regularly. Highest 140 (77.8%) respondents said television as the source of information in TB prevention. Majority (90%) of the respondents said of television as the information source on prevention of diarrhoeal diseases. Magazine and internet were mentioned by 20 (11%) respondents in each group as the information source. Regarding the sources of information on pregnancy related problems and solutions television was mentioned as the source of information by 156 (86%) of the respondents. Friends or relatives or teachers (67%), newspaper (64%), billboard (45%) and radio (44%) were other sources. Television was found as the main source of public health information to the people. Impact of print media in disseminating public health messages was mentioned very satisfactory by 24% and electronic media by 77% respondents. The mass media can be very much effective in getting public health messages to the community in developing countries. In view of our findings, it may be recommended that television, newspaper and billboards may be used as tools for reaching out that the use of these media should be strengthened further.

EMCJ. January 2022; 7(1): 21-25
Ruolo dell’Infermiere di Famiglia e di Comunità nell’assistenza dei pazienti in dialisi domiciliare e possibili effetti sugli outcome assistenziali
Authors: Burrai Francesco , Gambella Margherita , Micheluzzi Valentina
Published: November 2022

From the analysis of the national and international literature and considering the socio-demographic changes, it is necessary to rethink the organizational models capable of giving concrete answers to the new health and welfare needs of the population. The progressive increase of the elderly population and of people with at least one chronic disease and the SARS-CoV-2 pandemic have highlighted the need for a health and social system close to the population, which increases the territorial assistance, in particular at the patient’s home. Home care must become an elective place for prevention and health promotion activities. PNRR funds for proximity networks, telemedicine and innovation in the health field will enable assistance to be directed towards a new organizational and operational perspective, where the family and community nurse will play a key role. In the care of patients on home dialysis the evidence described in the literature reports the benefits of home hemodialysis treatment, in which the nurse of the family and community through his care skills, technical and psychological counselling, tele assistance and e-health can be integrated into the home care path, assisting the patient and the family unit and supporting them in the different health needs, especially in the quality of life outcome.
Return To Workplace Fears During Covid-19
Authors: Gibaldi Carmine , McCreedy Ryan
Published: November 2022

This article reports the observations of fear in the workforce while returning to the workplace following the SARS-CoV-2 (COVID-19) pandemic in comparison to previous research on fear in the workplace. Additionally, the findings contribute to the body of knowledge of workplace fears following collective, traumatic events. For the study, a sample of 189 employees were asked 16 questions which were measured on a Likert-type scale, in addition to a free response question on fear management strategies. Distributions of participants encompassed all levels of management. Results indicate primary return to workplace fears of conveying disease to loved ones and national mismanagement of crisis. Additional analysis indicates significant increases in fears stemming from coworker mistrust and career advancement inhibition with decreased fears of being laid off or fired, over baseline conditions. Further, the study observes significant increases in coping strategies such as nutrition and social problem management (such as therapy and socializing) and a decrease in problem management via cognitive adjustments or disengagement. This research suggests that employers take care when crafting their return-to-work strategies to foster trust among coworkers, facilitate opportunities to collectively reflect on traumatic experiences, and provide flexibility in accommodations for individuals’ unique circumstances.
Bycatch in the West Greenland lumpfish fishery, with particular focus on the common eider population
Authors: Merkel FR , Post S , Frederiksen M , Bak-Jensen Z , Nielsen J , Hedeholm RB
Published: November 2022

Incidental bycatch is a well-known challenge in gillnet fisheries throughout the world, and the fishery for North Atlantic lumpfish Cyclopterus lumpus roe is no exception. In Greenland, the fishery was Marine Stewardship Council-certified in 2015 but has pending conditions related to bycatch quantification, enforcement and mitigation strategies. To improve this situation and to assess the potential impact of bycatch, we collected independent on-board observer data on non-target fish and seabirds over 2 seasons (2019 and 2021). We recorded 6 fish species, but the only species constituting >1% of the lumpfish landings was the spotted wolffish Anarhichas minor. The bycatch of fish likely had little impact on the involved fish stocks. We recorded 4 seabird species, of which common eider Somateria mollissima was most common. When extrapolated to the entire West Greenland lumpfish fishery, the estimated bycatch of common eider was considerably higher in 2019 (19938; 95% CI: 3486-59661) than in 2021 (9802: 1260-29940) due to a longer fishing season in 2019. On average, for 2019 and 2021, the bycatch was modelled to reduce the growth potential for the West Greenland winter population by 51%. In comparison, the current hunting level (16538 birds yr-1) reduced the growth potential by 30%. The larger impact of bycatch was mainly due to a larger proportion of adults and females being targeted. The common eider bycatch impacts mainly the breeding population in Canada and Southwest Greenland and less so in Northwest Greenland. As mitigation, we recommend temporal closures of the fishery unless modified gillnets, which markedly reduce bycatch, become available.
Cardiovascular Risk Factor Control in Type 2 Diabetes Mellitus and New Trial Evidence
Authors: Nilsson Peter M.
Published: November 2022

The micro and macrovascular complications of Type 2 diabetes mellitus are influenced by several well described cardiovascular risk factors such as hyperglycaemia, hypertension, hyperlipidaemia, and smoking alongside age, sex, and diabetes duration. Modern guidelines have defined treatment and goals for these risk factors based on evidence. As new trials are constantly published, these risk factors must be analysed for evidence to contribute to guidelines that are being revised. During recent years three new trials (EMPA-REG, LEADER, and SUSTAIN-6) have shown that treatment of hyperglycaemia with new anti-diabetic drugs has been able to reduce a composite cardiovascular endpoint. This is a great achievement and is the focus of this review, which also summarises developments in the treatment of other relevant risk factors. Ultimately, a high-quality level of diabetes care also needs to involve a well-informed and motivated patient; if compliance is suboptimal the benefits of modern treatment will not be reached.
The Role of Insulin Resistance on FGF-21 and Inflammatory Markers in Obese Adolescents Undergoing Multicomponent Long-Term Weight Loss Therapy
Authors: Munhoz da Silveira Campos Raquel , Missae Oyama Lila , Landi Masquio Deborah Cristina , de Castro Ferreira Vicente Sofia Emanuelle , Campos Corgosinho Flávia , Pelissari Kravchychyn Ana Claudia , Tock Lian , Tufik Sergio , Túlio de Mello Marco , Dâmaso Ana R.
Published: November 2022

Objective: The purpose of this study was to investigate the effects of a long-term weight loss therapy in two groups (insulin resistance [IR] and non-insulin resistance [non-IR]) of obese adolescents based on metabolic profile, biomarkers of inflammation, and fibroblast growth factor-21 (FGF-21) concentrations.

Methods: Obese adolescents (15–19 years) were randomised into two groups (IR=8 and non-IR=9) and monitored through clinical, exercise training, nutritional, and psychological counselling over 1 year. Measurements of inflammatory biomarkers and FGF-21 were performed. The effects of therapy were verified by two-way ANOVA and post hoc analyses were performed (α ≤5%).

Results: A reduction in body mass, visceral fat, and an increase in adiponectin in both groups was found. Only the non-IR group demonstrated improved BMI, body fat mass, lean body mass, and waist circumference. Indeed, in the non-IR group, FGF-21 presence was positively correlated with high-density lipoprotein cholesterol and lean body mass and inversely correlated with plasminogen activator inhibitor-1 and triglycerides. In the IR group, there was a reduction in FGF-21 concentration, adiponectin/leptin ratio, insulin, total cholesterol, low-density lipoprotein cholesterol, and plasminogen activator inhibitor-1. FGF-21 was negatively correlated with delta-triglycerides, waist circumference, and low-density lipoprotein cholesterol. The IR prevalence reduced from 47% to 23.5% in the studied population.

Conclusions: Although the multicomponent clinical approach improves, in both analysed groups and in both metabolic and inflammatory states, the presence of IR resulted in a reduction in both FGF-21 concentration and adiponectin/leptin ratio. Additionally, in the IR group, FGF-21 was negatively correlated with proinflammatory markers, and in the non-IR group it was positively associated with high-density lipoprotein, suggesting its role in the control of inflammation counteracting IR. In this way, we suggest that IR can impair the anti-inflammatory effects of FGF-21. It will be helpful if these results can be confirmed in a large cohort, underlying physiological mechanisms to explore how these results can help in setting up more prospective studies.
Making the Invisible Visible: The Hidden Cost of Paediatric Inflammatory Bowel Disease
Authors: Turner Dan
Published: November 2022

This year, the European Society for Gastroenterology Hepatology and Nutrition (ESPGHAN) joined forces with the European Federation of Crohn’s & Colitis Associations (EFCCA) to drive awareness of the hidden costs of paediatric inflammatory bowel diseases (IBD) and make the invisible visible. This feature puts the hidden cost of paediatric IBD in the spotlight and the author makes the case for policy makers to recognise the invisible cost of paediatric IBD. He pledges to take four key steps to reduce the burden of the diseases on society and improve the lives of children and their families.
Identification of trinitrotoluene (TNT) in the far IR region using a parametric laser
Authors:   Siberian State University of Geosystems and Technologies, Ayrapetyan V. S. , Shaburova A. V. ,   Siberian State University of Geosystems and Technologies
Published: November 2022

Computational and experimental studies of the amplitude-time and spectroscopic characteristics of an IR parametric laser based on mercury thiogallate with frequency tuning in the range from 5 to 9 mi-crons, an output energy of 10 MJ and a spectral emission width of ≤ 0,7 cm-1 have been carried out. A multifunctional IR parametric laser complex for remote detection and identification of atmospheric gases, including explosive and chemically aggressive substances in the range of electromagnetic wave-lengths from 1,41–9,07 microns, by differential absorption and dispersing has been developed, created and tested. The paper presents the results of computational and experimental studies on remote determination of spectroscopic characteristics of the most famous explosives TNT, RDX, PETN. It shows the possibility of highly sensitive determination of the concentration (~1 ppm) of explosives using a multifunctional optical system based on an IR parametric laser.
Provision of geoinformation connectivity of the territory based on the spatial data infrastructure development
Authors:   Scientific Geoinformation Center of the Russian Academy of Sciences, Avdeev V. A. , Yablonskiy L. I. ,   Scientific Geoinformation Center of the Russian Academy of Sciences
Published: November 2022

One of the directions of the Strategy of scientific and technological development of the Russian Fed-eration, which ensures the connectivity of the territory through the creation of intelligent transport and telecommunication systems, is considered. It is proposed to introduce an integral part into the struc-ture of this direction – geoinformation connectivity of the territory. The dependence of geoinfor-mation connectivity on the level of spatial data provision of the country's territory is substantiated. It is stated that timely geoinformation provision can be achieved through the development of the state spa-tial data infrastructure. The problematic issues of geoinformation connectivity of the state territory and the formation of the state spatial data infrastructure to ensure the connectivity of the territory are iden-tified. It is established that the most successful and systematic construction and development of spatial data infrastructure is carried out within the framework of defense activities with the constant im-provement of the unified automated system for providing geospatial information (EASO GPI). In the conditions of sanction measures and technological isolation, in order to achieve a stable and complete geoinformation connectivity of the territory, the necessity of creating an independent state spatial data infrastructure based on the adaptation and development of a functioning EASO GPI is determined.
Creation of river network model for thematic map using GIS technology
Authors:   Siberian State University of Geosystems and Technologies, Byamba Оyunkhand , Kasyanova E. L. ,   Siberian State University of Geosystems and Technologies
Published: November 2022

The issues of creating a model of the Mongolian river network as a basis for thematic maps using GIS technologies are highlighted. The characteristic of the river network of Mongolia is considered, be-cause when constructing a digital model, it is necessary to convey its density and structure. Digital re-lief models (DEM) are widely used in the creation and updating of hydrological models of the surface. As the initial information for the creation of the DEM of Mongolia, the satellite images of SRTM of spatial resolution with a step of 30x30 square meters, which are used, are in the public domain. On the basis of this DEM, a new model has also been created of the river-only commercial network of the Khentii district of the Aimag of outer Mongolia for thematic mapping by means of GIS technologies. The order of the river distribution network development was determined by the features of the Strahler method in ArcGIS Spatial Distribution Analyst using special tool "Hydrology". As the result of study a vector hydrographic economic model with a database containing information on river networks is cre-ated. The object of the study is the river network of the Khentii district of the Aimag of outer Mongo-lia, belonging to the Pacific Basin.
The infrastructure concept for a single geo-information centre for forest management (part 1)
Authors:   St. Petersburg State Forest Technical University named after S. M. Kirov, Vagizov M. R. , Zayats A. M. ,   St. Petersburg State Forest Technical University named after S. M. Kirov
Published: November 2022

The article offers the concept of a single specialized complex for management, data analysis and peri-odic monitoring of the forestry fund spatial data of the Russian Federation based on centralized server architecture of geoinformation centre and innovative information technologies. The objective of the study is to improve the quality of management, updating and periodic monitoring of spatial data on the forest fund of the Russian Federation. As research methods, a server-side strategy for the develop-ment of a geoinformation centre and the organization infrastructure of the main types of geospatial data used in forestry are proposed. To implement the development, the methodological substatiation for the application of the proposed conceptual solutions in accordance with the territorial peculiarities of the organization of forestry in Russia is revealed. As a result of the research, in the first part of the article, the concept of the infrastructure of a single geoinformation center for forest management is formed, which will provide information about the forest area and integrate visualization of geospatial forestry data at different territorial levels of information representation. Well-timed provision of relia-ble forestry information will not only improve the quality of forest management, but also allow more selective forest management activities, taking into account the important ecosystem significance of forests.
Geoinformation study of the Ob river in the aspect of the digital economy development in Novosibirsk City
Authors:   Siberian State University of Geosystems and Technologies, Donskaya A. E. , Radchenko L. K. ,   Siberian State University of Geosystems and Technologies
Published: November 2022

The article considers the need for a methodology for creating a geoinformation model of the Ob River, which is organized as a set of spatial objects that reflect the current state of the Ob River and related objects within its borders, participating in the digital economy of the city. Attracting investments is one of the main tasks of economic developing of any city. One of the well-timed and effective measures to support investors' initiatives is the placement of up–to-date information about investment-attractive objects. Recently, the land management and urban planning industry has been developing at a high speed, which contributes to the requests of citizens, specialists in various industries to search for data on the state and development of a particular territory in various areas of activity, as well as obtaining comprehensive information about the current state of affairs and the forecast for its further develop-ment. There is no geoinformation model (GIM) where you can immediately get all the necessary in-formation, so this forces the user to collect information piecemeal from various departmental portals. The correctness of making any decisions, the degree of financial or other risks largely depends on the information received. This is confirmed by the fact that not just cartographic materials have become in demand, but unified information spaces containing not only diagrams of the current state of the object, but also a complete database of mapped objects. The introduction of such a river GIM will make it possible to systematize and maintain geospatial data, which in the future may lead to positive econom-ic effects. The main difference of the developed GIM is the created database, which is activated if necessary, and geoinformation tasks are solved with the help of it. The user can view each layer of the model separately, or combine several layers at once, or select and view individual information from different layers, thereby fulfilling the strategic objectives of the Digital Economy of the Russian Fed-eration program. The general geographical basis and thematic content of the Ob River geoinformation model are described. A fractional technological scheme for creating a geoinformation model of the Ob River has been developed. A description of the structural content of attribute tables is given, and a library of map symbols for displaying general geographic and thematic elements is developed.
Analysis of methods and tools of artificial intelligence for analysis and interpretation of active remote sensing data
Authors:   Siberian State University of Geosystems and Technologies, Kolesnikov A. A.
Published: November 2022

Remote sensing data, like most types of spatial data, are complex, dynamic, semi-structured, which makes it difficult to create an unambiguous and universal process for their processing and use. At the same time, the development of hardware, methods and algorithms of artificial intelligence and ma-chine learning has led to the fact that the areas of information technology are used in almost all areas of science and technology, including the processing of spatial data. The article formulates the main difficulties and tasks of processing remote sensing data, presents the most common methods and tools for their processing at present, using artificial intelligence technologies to automate processes. The possibilities of using specific algorithms and methods of artificial intelligence for all stages of pro-cessing data from active remote sensing are considered.
System analysis of the subsurface use sphere
Authors:   Ural State Mining University, Lebedev Y. V. , Krylov V. G. ,   Ural State Mining University
Published: November 2022

The purpose of this work is to develop conceptual approaches that include the basic concepts, mean-ings, tasks and criteria for their solution, ensuring the collective success of specialists in the field of subsurface use at all stages of its implementation, including those capable of creating productive ways of interdisciplinary communication and mutual understanding between business structures, geologists, topographers, ecologists, economists and sociologists. We note the practical relevance of this task, the solution of which requires the elaboration of theoretical concepts of the subsurface use system, taking into account current trends in the transition to a "green" economy and energy. Overcoming these diffi-culties is, in our opinion, a necessary result, since significant achievements have not yet been observed here. Taking into account the achievement of this goal, the article analyses the state of the problem of an interdisciplinary approach to the "sphere of subsurface use" in the context of new challenges, risks and uncertainties. It is shown that at present the "sphere of subsurface use" is considered as divided into separate fragments that require the attention of different specialists: in the field of geology, geophysics, geography, territorial planning, engineering, ecology, economics, sociology, management, etc. The essence of the interdisciplinary approach is considered, including a formalized model of the "sphere of subsurface use", characterized by the space of state and management parameters, efficien-cy criteria. The formal formulation of the problem of optimizing the management of a certain "subsur-face use system" is given, the main functionality with criteria requiring optimization is presented. The urgency of solving such problems is emphasized, the "correctness" of the criteria choice in which reflects the content of the current economic policy and can become a powerful factor in the socio-economic development of Russia and its regions. The technical and mathematical aspects of the multicriteria problem being solved are specified.
Monitoring changes in the state of vegetation cover on the section of the Sakhalin-2 project pipeline route according to space imagery data
Authors:   Institute of Marine Geology and Geophysics of the Far Eastern branch of the Russian Academy of Sciences, Verhoturov A. A. , Melkiy V. A. ,   Institute of Marine Geology and Geophysics of the Far Eastern branch of the Russian Academy of Sciences, Dolgopolov D. V. ,   Autonomous non-profit organization of higher education "Innopolis University", Lisitsky D. V. ,   Siberian State University of Geosystems and Technologies
Published: November 2022

The construction of underground main oil and gas pipelines leads to significant changes in natural landscapes. During the construction of main pipelines, felling of forest massifs is carried out. There is a high probability of the development of exogenous geological processes in the presence of mountain-ous relief and abundant precipitation. Revegetation control of pipelines is very important, and special attention should be paid to control when laying pipelines through specially protected natural areas. The article presents the results of assessing the nature and dynamics of the restoration of the vegetation cover on the section of the Sakhalin-2 gas pipeline in the Dolinsky sanctuary based on the results of calculating NDVI from satellite images using geoinformation technologies, and checking the results by field research data. The purpose of the research is to analyze the change in the state of the vegetation cover, determined by the volume of phytomass (calculation by NDVI) based on space monitoring da-ta. Methods: interpretation and analysis of space images from spacecraft of the Landsat and Sentinel-2 family for the period from 2001 to 2021, geoinformation mapping of changes in the state of vegetation on the ArcGIS platform. Results: 5 stages of change in the state of the vegetation cover in the studied time interval were identified. The results show revegetation 10 years after the completion of the pipeline. Good restoration of valley forests and grass cover was noted. Sparse vegetation is com-mon in sections of the pipeline where biological reclamation has not been carried out. As result of work carried out, an increase in NDVI revealed, and, consequently, the presence of good conditions for the growth of plant communities, typical for the investigated section of the pipeline of the Sakhalin-2 project after completion of construction work.
Mobile laser scanning data registration using aerial photography results based on computing relative position of point clouds
Authors:   Siberian State University of Geosystems and Technologies, Altyntsev M. A.
Published: November 2022

One of the most rapid surveying methods of terrestrial survey is mobile laser scanning (MLS). This method allows collecting data for objects of the environment with high detail and accuracy in a short period of time. A condition for obtaining accurate MLS data is receiving a satellite signal of high quality. When scanning built-up urban areas, the quality of signal deteriorates, which leads to a decrease in accuracy. The use of additional control data, one of which may be aerial photography results, helps to compensate for the loss of accuracy. For this purpose, MLS data are registered using aerial photog-raphy data with various automatic methods, which are carried out in two- or three-dimensional space. Therefore, the three-dimensional MLS data are previously transformed into the form of a two-dimensional image or a group of aerial images into the form of a three-dimensional point cloud. Regis-tration in 3D space is preferred with low quality of aerial images. The technique of automatic MLS data registration to point clouds generated from aerial images using the ICP method is discussed. It is proposed to predivide the MLS data into fragments. It is shown that the size of fragments for calculating local corrections in horizontal position can differ from the size of fragments for calculating correc-tions in vertical one.
Study of the accuracy of UAV images captured by rolling shutter cameras
Authors:   Siberian State University of Geosystems and Technologies, Dedkova V. V.
Published: November 2022

Quite often aerial survey made by unmanned aerial vehicle (UAV) is carried out using digital non-metric cameras that have rolling shutters. Variations in speed of a UAV and its angular elements of exterior orientation during aerial survey cause distortions in the images generated by the camera, which affects the accuracy of the processing results. The article shows the variations in the elements of exterior orientation during the operation of a rolling shutter and describes the way of its detection by flight recorder. The values of image distortion, caused by the variations in the angular elements of the exterior orientation of a snapshot, are calculated for the Sony Alpha A6000 digital non-metric camera.
Integrated analysis of geodata to determine the prospects oil and gas bearing capacity: a case of study Bhima sedimentary basin, republic of India
Authors:   Limited Liability Company ", Loginov D. S. ,   Tselevoi Gorizont"
Published: November 2022

The article considers the author's experience in comprehensive analysis of geodata within the carto-graphic support of geological and geophysical research, aimed at determining the prospects of oil and gas bearing capacity of sedimentary basins. The study was carried out as part of the National Seismic Program (NSP) in 2016-2020. The article describes the current state topographic and geological maps of the Republic of India, as well as other geodata that were used during the processing and interpretation of field seismic data. The detailed analysis of geodata was carried out during the verification pro-cess of seismic profiles spatial positions that allowed to reveal errors in design of the original geophysical survey network (and their potential sources) within sedimentary basin of Bhima with perspective resources awaiting detection. The results of the analysis facilitated additional seismic surveying in the new field season to meet the baseline goals of the National Seismic Program of the Republic of India. The experience of integrated use of geodata and organization of a unified geoinformation space pre-sented in the article is relevant when conducting regional and prognostic-mineralogical studies on the territory of the Russian Federation in order to form and increase the fund of objects of prospecting reserve for the most important and scarce types of minerals.
Analysis of the geodynamic factors impact on the relativistic frequency shift of atomic standards
Authors:   Siberian State University of Geosystems and Technologies, Gienko E. G.
Published: November 2022

The impact of geodynamic factors on the relativistic frequency shift of atomic standards is analyzed. The results of frequency shift calculations caused by various geodynamic phenomena are presented, and the significance of these shifts for modern optical frequency standards is estimated. Based on the results of the assessment, it was concluded that for the relativistic frequency shift at the level of 10-18, the most significant factors are tides in the solid Earth and oceans, which are well taken into account using modern global tidal models. Nontidal phenomena in the oceans, which cause a change in the geopotential at the level of 0.2 m2/s2 (frequency shift of the order of 2·10-18), do not have much effect on the course of stationary atomic standards located on the continents. The postglacial uplift has a secular character and is well modeled at the present time. It is recommended to pay special attention to the complexly modeled potential changes caused by fluctuations in the water level in reservoirs (for stations located near reservoirs) and the groundwater level. The rest of the considered geodynamic ef-fects have practically no effect on the course of the optical clock.
Alaska – Siberia (AlSib) – transcontinental air bridge of World War II and its geospatial support by soviet surveyors and cartographers
Authors:   Siberian State University of Geosystems and Technologies, Osipov A. G. , Zharnikov V. B. ,   Siberian State University of Geosystems and Technologies
Published: November 2022

The purpose of the article is to find out the determining role and basic content of geospatial support of legendary airline Alaska – Siberia in the period of Great Patriotic War (1941–1945), its scientific and practical foundations, created in the period of prewar development of domestic geodesy, its organization structures, ensuring proper level of topographic and geodetic territorial knowledge of the country, and also scientific and industrial culture of its development. One of the most important objects of geo-spatial support in the prewar and initial period of the Second World War was the Alaska-Siberia transcontinental air bridge, which became the result and symbol of the military cooperation between the USSR and the USA, which delivered in the period 1942–1945 to Soviet Air Force about 10 thousand fighters, bombers and transport aircrafts, which played a huge and victorious role in the Second World War. The prewar achievements of Soviet geodesy and cartography in the field of topographic and geodetic knowledge of the country, minimization of "white spots" in the areas of the future air route, problems and solutions in relation to surveys, design and construction of airfields, which determined the required network of AlSib nodal points, are characterized. A number of names of participants in the creation of the route have been identified, among which, in particular, Safronov Sergey Niko-laevich, a surveyor engineer, later a well-known teacher and scientist, associate professor of NIIGAiK – SSGA, now SSUGT, was named.
Development of the Tuzla spit geosystem in the XIX–XXI Century
Authors:   Shirshov Institute of Oceanology RAS, Southern Branch, Krylenko V. V. , Krylenko M. V. ,   Shirshov Institute of Oceanology RAS, Southern Branch
Published: November 2022

The Tuzla Spit is a large accumulative coastal form located in the south of the Kerch Strait connecting the Azov and Black Seas. Economic activity on the sea coasts of the Azov-Black Sea region has been actively developing in recent decades. The load on coastal geosystems is increasing, disturbing natural balance in coastal development processes. Simultaneously global and regional changes of natural con-ditions (first climatic and hydrological) are happening. Monitoring coastline dynamics is a necessary component for successful coastal zone management. The analysis of the Tuzla Spit coasts dynamics in this article is based on the study of modern and archival geographical maps and remote sensing data. It has been established that in the last century both growth and erosion of this accumulative form were observed. In general, its dynamics is determined by the ratio of the incoming sediment volume and the nature of hydrodynamic processes in the Kerch Strait. A significant part of the changes in the Tuzla Spit in the 21 century was initiated by anthropogenic impact. In 2003, part of the coastline of the Tuzla Spit was stabilized technologically. In 2016-2020 road and railway bridges across the Kerch Strait were built, which run along the dam of the Tuzla Spit and Tuzla Island. At present, the Tuzla Spit is developing as a natural and technological geosystem.
THE INFLUENCE OF PHYSICAL EDUCATION PROGRAM IN IMPROVING K TO 12 POTENTIAL LEADERSHIP IN SELECTED UNIVERSITIES AND COLLEGES IN THE PROVINCE OF RIZAL: AN ASSESSMENT
Authors:   Assistant Professor De La Salle-College of Saint Benilde Antipolo City, Tianio Jomar S. , Tumala Arlyn S. ,   PhD. Assistant Professor, De La Salle-College of Saint Benilde Antipolo.
Published: November 2022

This chapter contains the introduction, background of the study, statement of the problem, hypotheses and assumptions, importance of the study, theoretical and conceptual framework, scope and delimitation of the study, and the definition of terms.
Nucleic acid vaccination strategies for ovarian cancer
Authors: Saha Chayanika , Bojdo James , Dunne Nicholas J. , Duary Raj Kumar , Buckley Niamh , McCarthy Helen O.
Published: November 2022

High grade serous carcinoma (HGSC) is one of the most lethal ovarian cancers that is characterised by asymptomatic tumour growth, insufficient knowledge of malignant cell origin and sub-optimal detection. HGSC has been recently shown to originate in the fallopian tube and not in the ovaries. Conventional treatments such as chemotherapy and surgery depend upon the stage of the disease and have resulted in higher rates of relapse. Hence, there is a need for alternative treatments. Differential antigen expression levels have been utilised for early detection of the cancer and could be employed in vaccination strategies using nucleic acids. In this review the different vaccination strategies in Ovarian cancer are discussed and reviewed. Nucleic acid vaccination strategies have been proven to produce a higher CD8+ CTL response alongside CD4+ T-cell response when compared to other vaccination strategies and thus provide a good arena for antitumour immune therapy. DNA and mRNA need to be delivered into the intracellular matrix. To overcome ineffective naked delivery of the nucleic acid cargo, a suitable delivery system is required. This review also considers the suitability of cell penetrating peptides as a tool for nucleic acid vaccine delivery in ovarian cancer.
The effects of vaccination on the disease severity and factors for viral clearance and hospitalization in Omicron-infected patients: A retrospective observational cohort study from recent regional outbreaks in China
Authors: Li Hongru , Zhu Xiongpeng , Yu Rongguo , Qian Xin , Huang Yu , Chen Xiaoping , Lin Haibin , Zheng Huiming , Zhang Yi , Lin Jiarong , Deng Yanqin , Zhong Wen , Ji Yuejiao , Li Qing , Fang Jiabin , Yang Xiaojie , Lin Rong , Chen Fangsu , Su Zhijun , Xie Baosong , Li Hong
Published: November 2022

Object

This study attempted to explore the effects of vaccination on disease severity and the factors for viral clearance and hospitalization in omicron-infected patients.

Methods

The clinical manifestations of 3,265 Omicron-infected patients (BA.2 lineage variant; the Omicron group) were compared with those of 226 Delta-infected patients (the Delta group). A Multi-class logistic regression model was employed to analyze the impacts of vaccination doses and intervals on disease severity; a logistic regression model to evaluate the risk factors for hospitalization; R 4.1.2 data analysis to investigate the factors for time for nucleic acid negativization (NAN).

Results

Compared with the Delta group, the Omicron group reported a fast transmission, mild symptoms, and lower severity incidence, and a significant inverse correlation of vaccination dose with clinical severity (OR: 0.803, 95%CI: 0.742-0.868, p<0.001). Of the 7 or 5 categories of vaccination status, the risk of severity significantly decreased only at ≥21 days after three doses (OR: 0.618, 95% CI: 0.475-0.803, p<0.001; OR: 0.627, 95% CI: 0.482-0.815, p<0.001, respectively). The Omicron group also reported underlying illness as an independent factor for hospitalization, sore throat as a protective factor, and much shorter time for NAN [15 (12,19) vs. 16 (12,22), p<0.05]. NAN was associated positively with age, female gender, fever, cough, and disease severity, but negatively with vaccination doses.

Conclusion

Booster vaccination should be advocated for COVID-19 pandemic-related control and prevention policies and adequate precautions should be taken for patients with underlying conditions.
Climate-induced migrant's hopeful journey toward security: Pushing the boundaries of gendered vulnerability and adaptability in Bangladesh
Authors: Khanom Sufia , Tanjeela Mumita , Rutherford Shannon
Published: November 2022

Every year 10,000 climate-induced migrants in Bangladesh leave their homes seeking safer locations away from the climate-induced disasters they have experienced. They commonly migrate to nearby urban areas or the capital city after losing their livelihoods in their place of origin. However, the unplanned urbanization, limited capacities of urban infrastructures, service sector deficiencies, man-made disasters, and other social vulnerabilities further push these migrants into an (in)secure state. Hopes of security and capacity to adapt in their new homes can be impacted by the patriarchal society where gender is often associated with unequal social relations and hierarchies. These might extend from every day to long term (in)security. This study draws on qualitative data collected as part of research conducted for two PhD projects. In both cases, climate-induced migrants were forced to migrate from their places of origin due to sea level rise, river erosion, and soil salinity to Dhaka (capital city) and Coxes Bazar (coastal city) of Bangladesh. In this context, are their adaptive capacities influenced by gender relations? How are these adaptive capacities shaped through different institutions? And, how can these adaptive actions improve/strengthen human security? Gendered power relations are the main analytical framework for this paper as power is an influential factor to shape adaptive capabilities. It argues that (in)security, as an outcome of unsustainable adaptability, further pushes climate-induced migrants in vulnerable conditions in their newly settled urban areas. The vulnerability, capacity to adapt, and (in)security are gendered. This will contribute to understand for whom, where, and how the exclusive adaptative initiatives would further place the climate-induced migrants in vulnerable and (in)secure conditions in their newly settled areas.
Adaptive human bodies and adaptive built environments for enriching futures
Authors: Andres Josh
Published: November 2022

As humans, we spend most of our lives inside human-built environments, such as homes, offices, and schools. In these built environments, humans co-create and share a collective awareness, social practices, and knowledge while computing machinery is designed to maintain the built environment and support our interactions. The effects of these technologically enriched built environments on humans are how our bodies adapt to the practices they promote and how these practices, in return, affect the built environment and the natural environment. This perspective paper uses inbodied interaction to frame the constant adaption of our bodies to our surrounding environment as an opportunity to inform the design of technology and its practices and offer a vision where humans, the built environment, and the natural environment coexist in a mutually beneficial relationship.
Evolving trends in epidemiology and natural history of cardiac amyloidosis: 30-year experience from a tertiary referral center for cardiomyopathies
Authors: Porcari Aldostefano , Allegro Valentina , Saro Riccardo , Varrà Guerino Giuseppe , Pagura Linda , Rossi Maddalena , Lalario Andrea , Longo Francesca , Korcova Renata , Dal Ferro Matteo , Perkan Andrea , Dore Franca , Bussani Rossana , De Sabbata Giovanni Maria , Zaja Francesco , Merlo Marco , Sinagra Gianfranco
Published: November 2022

Objective

Natural history of cardiac amyloidosis (CA) is poorly understood. We aimed to examine the changing mortality of different types of CA over a 30-year period.

Patients and methods

Consecutive patients included in the “Trieste CA Registry” from January 1, 1990 through December 31, 2021 were divided into a historical cohort (diagnosed before 2016) and a contemporary cohort (diagnosed after 2016). Light chain (AL), transthyretin (ATTR) and other forms of CA were defined according to international recommendations. The primary and secondary outcome measures were all-cause mortality and cardiac death, respectively.

Results

We enrolled 182 patients: 47.3% AL-CA, 44.5% ATTR-CA, 8.2% other etiologies. The number of patients diagnosed with AL and ATTR-CA progressively increased over time, mostly ATTR-CA patients (from 21% before 2016 to 67% after 2016) diagnosed non-invasively. The more consistent increase in event-rate was observed in the long-term (after 50 months) in ATTR-CA compared to the early increase in mortality in AL-CA. In the contemporary cohort, during a median follow up of 16 [4–30] months, ATTR-CA was associated with improved overall and cardiac survival compared to AL-CA. At multivariable analysis, ATTR-CA (HR 0.42, p = 0.03), eGFR (HR 0.98, p = 0.033) and ACE-inhibitor therapy (HR 0.24, p < 0.001) predicted overall survival in the contemporary cohort.

Conclusion

Incidence and prevalence rates of ATTR-CA and, to a less extent, of AL-CA have been increasing over time, with significant improvements in 2-year survival of ATTR-CA patients from the contemporary cohort. Reaching an early diagnosis and starting disease-modifying treatments will improve long-term survival in CA.
Left atrial function after standalone totally thoracoscopic left atrial appendage exclusion in atrial fibrillation patients with absolute contraindication to oral anticoagulation therapy
Authors: Marini Massimiliano , Pannone Luigi , Branzoli Stefano , Tedoldi Francesca , D’Onghia Giovanni , Fanti Diego , Sarao Emanuele , Guarracini Fabrizio , Quintarelli Silvia , Monaco Cinzia , Graffigna Angelo , Bonmassari Roberto , La Meir Mark , Chierchia Gian Battista , de Asmundis Carlo
Published: November 2022

Background

Left atrial appendage (LAA) is a common source of thrombi in patients with atrial fibrillation (AF). The effect on left atrial (LA) function of the Totally Thoracoscopic (TT)-LAA exclusion with epicardial clip is currently unknown. This study aims at evaluating the effect of TT-LAA exclusion on LA function.

Methods

Standalone TT-LAA exclusion with the clip device was performed in 26 patients with AF and contraindication to oral anticoagulation (OAC). A 3D CT scan, trans-esophageal echocardiography, spirometry and cerebrovascular doppler ultrasound were performed preoperatively. Clip positioning and LAA exclusion were guided and confirmed by intraoperative trans-esophageal echo. To evaluate LA function, standard transthoracic echocardiography and 2D strain of LA were performed before surgery, at discharge and at 3-month follow-up.

Results

The mean CHA2DS2-VASc and HASBLED scores were 4.6 and 2.4 respectively. There were no major complications during the procedure. At median follow-up of 10.3 months, 1 (3.8%) non-cardiovascular death, 1 (3.8%) stroke and 4 (15.4%) cardiovascular hospitalizations occurred. At 2D strain of LA, the reservoir function decreased significantly at discharge, compared to baseline and recovered at 3-months follow-up. Furthermore, NT-proBNP increased significantly after the procedure with a return to baseline after 3 months. Changes in E/A were persistent at 3 months.

Conclusion

Our data in a small cohort suggest that TT-LAA exclusion with epicardial clip can be a safe procedure with regards to the atrial function. The LAA amputation impairs the reservoir LA function on the short term, that recovers over time.
PCSK9 inhibitors in a renal transplant patient complicated with hepatitis B: A case report and literature review
Authors: Lv Pinchao , Li Yuxi , Wu Lin , Weng Haoyu , Chen Ming , Ding Wenhui , Li Jianping
Published: November 2022

Lipid metabolism disorders are recognized to be one of the most frequent complications of renal transplantation, while dyslipidemia and chronic kidney disease (CKD) are strong risk factors for arteriosclerotic cardiovascular disease (ASCVD). Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) are novel lipid-lowering drugs, the safety and efficacy of which are yet to be confirmed in transplanted patients. There have been several small-sample studies using PCSK9i in patients after heart transplantation, while fewer cases use PCSK9i after kidney transplantation. We report a case of a renal transplant recipient complicated with hepatitis B treated with PCSK9i, which achieved a remarkable lipid-lowering efficacy, and no significant adverse effects were found during the follow-up.