bluuebunny/crossref_metadata_2025 huggingface dataset:
EVALUATION OF ANTIBACTERIAL ACTIVITY OF TRICHILIA DREGEANA SOND (MELIACEAE) CRUDE EXTRACTS AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA
Authors: Mossie Tesfa , Kasa Temesgen , Urge Bekesis , Yifred Hilena
Published: December 2024

Medicinal plants have been playing a crucial role in drug discovery and development against infectious diseases. The antibacterial activity of methanol crude extract of traditionally used Trichilia dregeana Sond was evaluated against common bacterial pathogens. Agar well diffusion and broth dilution assays were used to evaluate the antimicrobial activity and MIC of crude methanol plant extracts. The methanol crude extract of Trichilia dregeana Sond showed promising antibacterial activity against all tested bacterial isolates. A significant difference (p < 0.05) was observed in susceptibility among Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa species isolates. A higher mean susceptibility or inhibition zone diameter to crude extracts was observed in Escherichia coli (19.6 ± 5.9 mm) and Pseudomonas aeruginosa (18.4 ± 5.9 mm) compared to Staphylococcus aureus isolates. Significant differences were also observed in the susceptibility of tested bacterial isolates at different concentrations of crude extracts. A higher inhibition zone diameter was recorded in Pseudomonas aeruginosa (27.2 ± 1.5 mm), followed by Escherichia coli (25.2 ± 1.5 mm), and Staphylococcus aureus (21.1 ± 1.4 mm) at a concentration of 100 mg/mL. A comparable inhibition zone of crude extracts was observed with that of the positive control at 100 mg/mL concentration against Staphylococcus aureus and Escherichia coli isolates. The findings indicated that bacterial growth inhibition increased as the concentration of the crude extracts increased. All tested pathogenic bacteria species (gram-positive and gram-negative) were susceptible to plant leaf extract, even at lower levels of concentration. This showed the plant extracts’ broad-spectrum activity against both gram-positive and gram-negative bacteria. The methanol crude extract of plants is an effective antibacterial agent for treating bacterial infections since the extract showed significant antibacterial potency comparable with that of the standard antibiotic disk. The findings are promising and encourage further investigation of the crude extracts’ phytochemical, toxicological, and pharmacological aspects to support their potential rational use in antimicrobial therapy.
STRATEGIC NETWORK PLANNING FOR OPTIMIZING DIGITAL TRANSFORMATION IN THE COAL MINING INDUSTRY
Authors: Pratama Rizqi , S Angga Margi , Farzan Arisal
Published: December 2024

The coal mining industry is one of the most important sectors in Indonesia's economy, and it has become a vital part of the national economy. As a result, the mining industry has become more and more digital. The application of the overlay method in this study aims to improve operational efficiency and work safety in the coal mine of PT Putra Perkasa Abadi (PPA) in Indonesia. The overlay method combines WiFi and LTE networks in the mining area, which improves network performance in terms of throughput, latency, packet loss, and signal coverage. The implementation of Strategic Network Planning to Optimize Digital Transformation in the Coal Mining Industry has proven to be effective in improving the quality of networks that support digital transformation in mining areas. The solution has the potential to be applied to other industrial sectors with similar operational challenges, optimizing the use of network technologies to support sustainability and productivity. Overall, this study makes a significant contribution to designing and implementing network systems that can support operational efficiency, improve occupational safety, and offer sustainable and adaptive solutions in the industry, ultimately supporting the digitalization and transformation of the industry.
THE LEGAL PROTECTION OF PATENTS ON PHYTOPHARMACEUTICAL PRODUCTS IN INDONESIA: CASE STUDIES AND THEORETICAL PERSPECTIVES
Authors: Tjandrawinata Raymond R. , Budi Henry Soelistyo
Published: December 2024

Indonesia has great potential in the development of biowealth-based phytopharmaceutical products, considering its rich natural wealth and traditional medicine traditions. This study uses theories of legal utilitarianism, distributive justice, and legal positivism to explore the challenges facing Indonesia, as well as opportunities for more inclusive and adaptive reforms. This analysis employs a normative juridical approach, focusing on the analysis of written laws, regulations, doctrines and legal interpretations related to patent protection for phytopharmaceutic products. This approach enables a thorough understanding of the patent legal framework in Indonesia and its practical implementation. The case study method is used to evaluate several patents registered with the Directorate General of Intellectual Property (DJKI). The results show that Indonesia is facing a number of complex legal challenges in the patent registration process, ranging from barriers to novelty criteria and inventive steps to lengthy administrative processes. In addition, Indonesia needs to strengthen its national patent system and intellectual property protection strategies to ensure that local communities benefit fairly from the use of their traditional knowledge. This research could investigate how these mechanisms influence innovation within local communities and their role in fostering sustainable practices.
Evaluasi Program Pembinaan Minat Bakat Anak Berkebutuhan Khusus di Sekolah Luar Biasa Prof. Dr. Sri Soedewi Kota Jambi
Authors: Munandar Aris , Soleha Siti , Wardani Miki , Weni Weni , Safa Azra Salsabilla
Published: December 2024

Pendidikan inklusif di Indonesia semakin berkembang, termasuk dalam pengembangan minat dan bakat Anak Berkebutuhan Khusus (ABK). Sekolah Luar Biasa (SLB) Prof. Dr. Sri Soedewi Kota Jambi menjadi salah satu institusi yang memiliki peran penting dalam pengembangan potensi tersebut. Evaluasi program pembinaan ini diperlukan untuk menilai efektivitas program dan kontribusinya terhadap pengembangan siswa. Penelitian ini bertujuan untuk mengevaluasi Program Pembinaan Minat Bakat pada Anak Berkebutuhan Khusus di Sekolah Luar Biasa (SLB) Prof. Dr. Sri Soedewi, Kota Jambi. Menggunakan metode deskriptif kualitatif, data dikumpulkan melalui wawancara, observasi, dan studi dokumentasi, dengan triangulasi sumber untuk memastikan keabsahan data. Hasil penelitian menunjukkan bahwa sekolah memiliki komitmen yang kuat dalam mengembangkan potensi siswa sesuai dengan karakteristik masing-masing, dengan melibatkan orang tua dalam proses identifikasi dan pengembangan minat serta bakat anak. Namun, penelitian ini juga mengidentifikasi tantangan yang dihadapi, termasuk masalah aksesibilitas, metode pengajaran yang kurang efektif, dan dukungan emosional yang diperlukan untuk meningkatkan minat belajar siswa. Evaluasi program dilakukan secara berkala dengan menggunakan model CIPP (Context, Input, Process, Product), yang memungkinkan penilaian menyeluruh terhadap konteks pendidikan, sumber daya, proses pembelajaran, dan hasil yang dicapai. Kesimpulan dari penelitian ini menekankan pentingnya perancangan program yang sesuai dengan kebutuhan individu siswa, serta peran kualitas guru, keterlibatan orang tua, dan dukungan masyarakat dalam meningkatkan hasil pendidikan bagi anak berkebutuhan khusus. Penelitian ini diharapkan dapat memberikan wawasan berharga bagi pendidik dan praktisi di bidang pendidikan khusus.
Strategi Pemasaran Efektif terhadap Keputusan Pembelian Teh Break di Kota Lamongan
Authors: Kumala Imtinan Widhah , Askhar Bayu Malikhul , Yusuf Mohamad Fahmi , Pratama M Adhitya Nugraha , Maulida Fauziah
Published: December 2024

This study aims to analyze the influence of customer satisfaction, strategic location, and promotion on consumer purchasing decisions in teh break businesses in Lamongan. The research method employed is Structural Equation Modeling (SEM) based on Partial Least Squares (PLS), with data collected through a survey of 100 respondents selected using the purposive sampling technique. The results reveal that all independent variables, namely customer satisfaction, strategic location, and promotion, positively and significantly affect consumer purchasing decisions. Strategic location has the greatest influence (β = 0.412; t-statistic = 5.673), followed by customer satisfaction (β = 0.321; t-statistic = 4.256) and promotion (β = 0.287; t-statistic = 3.892). The research model explains 65.2% of the variance in purchasing decisions (R² = 0.652). This study highlights the importance of strategic location, customer satisfaction, and promotion in shaping purchasing decisions. The findings are expected to serve as a reference for teh break business owners in formulating more effective marketing strategies.
Memahami Populasi dan Sampel: Pilar Utama dalam Penelitian Kuantitatif
Authors: Mushofa Mushofa , Hermina Dina , Huda Nuril
Published: December 2024

This paper explains the importance of paying attention to research subjects in a study whose existence is a bridge between theory and practice. Because it focuses on quantitative methods, it only discusses population and samples. The method used is library research with a qualitative descriptive approach. After conducting the research, it can be concluded that population refers to the entire subject or object that is the target of research, while the sample is part of the population chosen to represent the entire population. The selection of the right population and sample is very important in research because this will affect the quality of the data, the accuracy of the results, and the conclusions drawn.
Investigation of Waste Mineral Wool in Geopolymer Production
Authors: Mohabbı Mehrzad , Kolak Mehmet Nuri
Published: December 2024

Mineral wools are widely used insulation materials in the construction industry; however, their non-recyclable nature poses an environmental challenge. In this study, mineral wool wastes were sustainably utilized by grinding them into powder and activating them with Na₂SiO₃ and NaOH solutions. During the production process, different silica modulus ratios of Na₂SiO₃ (2.0, 2.5, and 3.0) were examined, and the optimal ratio was determined to be 2.5. The mechanical properties of the samples were evaluated after curing at various temperatures (25°C, 50°C, 75°C, and 100°C), with the maximum compressive strength of 59.2 MPa observed in glass wool samples. Thermal curing enhanced compressive strength, particularly at 75°C, for glass wool-based samples. Additionally, the compressive strengths of the samples stabilized after a curing period of 90 days. These findings demonstrate the feasibility of recycling mineral wool wastes into high-performance materials and highlight the significant role of thermal curing in enhancing mechanical properties.
GLOW DISCHARGE IN HELIUM AND NITROGEN ATMOSPHERES AT STELLARATOR URAGAN-2M
Authors: Martseniuk Yu.P. , Kovtun Yu.V. , Lozin A.V. , Shapoval A.N. , Makhov M.N. , Moiseenko V.E. , Yevsiukov O.V. , Korovin V.B. , Kramskoy E.D. , Kozulya M.M. , Baron D.I. , Maznichenko S.M. , Krasiuk A.Yu. , Listopad V.M.
Published: December 2024

Investigations of glow discharge on the Uragan-2M stellarator in helium and nitrogen atmospheres have been carried out. Studies were made in the range of discharge currents from 0.05 to 1 A and working gas pressure from 0.284 to 14.93 Pa. The current-voltage characteristics of the glow discharge were measured. The floating potential along the minor radius was measured using a single probe. In the optical emission spectrum of the plasma, spectral lines of excited He I atoms in the He atmosphere were observed. In the N2 atmosphere, spectral lines of excited molecules N2*
and molecular ions N2+* were also registered.
SPATIAL DISTRIBUTION OF ELECTRIC FIELD IN A TWO STAGE HALL TYPE PLASMA SOURCE
Authors: Bazhenov V.Yu. , Dobrovolskii A.M. , Tsiolko V.V. , Piun V.M.
Published: December 2024

The two-stage plasma source of Hall type having common anode and two cathodes residing at locations with essentially different magnetic field configuration is experimentally studied. Considered are peculiarities of spatial distribution of floating potential measured by moved Langmuir probes. In particular, it was established that in the middle plane of the anode on the axis of the device, the value of the floating potential of the plasma is up to 95% of the anode voltage.
FEATURES OF ENHANCED PLASMA COMPRESSION UNDER EXTERNAL MAGNETIC FIELD
Authors: Volkova Yu.Ye. , Garkusha I.E. , Makhlai V.A. , Solyakov D.G. , Herashchenko S.S. , Petrov Yu.V. , Yelisyeyev D.V. , Shevchuk P.B. , Siromolot Yu.V. , Kulik N.V. , Lebedev S.I. , Aksenov N.N. , Grekov D.L. , Merenkova T.M.
Published: December 2024

The impact of an external longitudinal magnetic field on a self-compressed quasi-stationary plasma flow generated by a high-current magnetoplasma compressor is studied. The additional magnetic field of 0.24 T was applied to the plasma discharge. A significant enhancement of flow compression when an external longitudinal magnetic field is applied was found. The magnetic field also influences the process of current vortices formation, which is linked to the conversion of kinetic energy into magnetic field energy. The formation of fewer vortices inthe presence of the magnetic field suggests more efficient compression and potentially higher plasma parameters in the compression zone.
FRACTAL MODEL FOR ASSESSING THE MICROHARDNESS OF LOW-CARBON ALLOY STEEL AFTER CARBURIZATION
Authors: Romaniuk S.P. , Nowakowska-Langier K. , Volchuk V.M. , Taran A.V. , Nesterenko Ye.O.
Published: December 2024

The hardened surface of automatic transmission gear has been investigated by using fractal theory. Scanning electron microscopy (SEM) with microanalysis (EDX) were used to study the surface morphology and distribution of chemical elements of the hardened part. The carbon distribution on the surface as well as the influence of chromium on carbon diffusion during carburization have been investigated by using fractal theory. Structural changes via the cross section of the carburized layer were studied by measuring fractal dimensions. Comparison of
the fractal dimensions and the level of microhardness over the cross section of hardened specimens allowed rapid assessment of the structural state increasing the tool service life. The results showed that both the mechanical properties and the surface fractal dimensions of the AISI 5120 steel differed greatly depending on the carbon concentration.
STUDY OF THE IGNITION VOLTAGE OF A NEGATIVE PULSED CORONA DISCHARGE IN OXYGEN WITH COMBINED POWER SUPPLY
Authors: Kadolin B.B. , Taran G.V. , Zavada L.M. , Yegorov M.O.
Published: December 2024

The study investigates the ignition of a negative pulsed corona discharge in oxygen in plasma-chemical reactors with a multi-pin segmented cathode. The dependence of the ignition voltage on the amplitude of the low-voltage DC applied in intervals between high-voltage pulses is presented. It is shown that under all investigated experimental conditions, the ignition voltage Ui decreases monotonically with the growth of Udc/d. It is also demonstrated that electrode shielding leads to an increase in ignition voltage.
TRANSITION MODE OF MAGNETRON DISCHARGE WITH ANODE SHEATH
Authors: Zykov A. , Dudin S. , Yakovin S. , Sydorenko V.
Published: December 2024

The characteristics of the combined Magnetron Ion-Plasma System (MIPS) in the transition mode, which is optimal for the synthesis of nanostructured coatings on heat-sensitive materials, are presented. The system consists of a magnetron sputtering system and a Hall-type ion source with a common magnetic system and two power supply units. It was found that the presence of a positive magnetically insulated anode leads to a 2-3 times decrease in the gas pressure threshold of the magnetron discharge extinction as a result of the appearance of a transient mode. In this regime, a significant dependence of the anode potential of the ion source on the gas pressure and the magnetic field is observed.
OPTICAL EMISSION SPECTROSCOPY OF PLASMA OF MAGNETRON DC DISCHARGE IN ARGON WITH COPPER AND MOLYBDENUM VAPOURS ADMIXTURES
Authors: Murmantsev A. , Veklich A. , Kostyukevych O. , Nedybaliuk O.
Published: December 2024

Magnetron discharge plasma with copper and molybdenum vapours admixtures are investigated by means of optical emission spectroscopy. A copper disk target, which partially covered by molybdenum semicircle, was used to generate the plasma with Cu and Mo vapour admixtures in a magnetron sputtering system. The optical emission of such plasma was registered in the spectral range of 440…910 nm. The discharge was realized in an argon atmosphere at pressures of 1.3, 6.7, 13.3, and 53.3 Pa in currents range from 50 to 300 mA. Excitation temperatures of argon and metals’ atoms were determined by Boltzmann plot technique based on emission intensities of Ar I, Cu I, and Mo I spectral lines.
Comparative Morphological Response of Wheat Genotypes (Triticum aestivum L.) to Potassium Treatments Under Irrigated and Terminal Drought Conditions
Authors: Farooq Umar , Basit Abdul , Ul Hassan Faiz , Kainat Mishal , Abu Bakar Zia Muhammad
Published: December 2024

Worldwide wheat productivity faces limitations due to environmental stresses, of which drought is a key factor, necessitating effective nutrient management strategies such as potassium (K) application to enhance stress tolerance and yield stability. Field experiments were conducted during the 2022-23 growing season to analyze the response of different genotypes to K concentrations under terminal drought conditions (TDC). Field experiments conducted during the 2022-23 growing season analyzed the response of eight wheat genotypes to three potassium concentrations (K1: 0%, K2: 1%, K3: 2%) under TDC. The study showed a significant positive correlation between yield and several plant parameters, including height, panicle length, number of spikelets, flag leaf area, yield per plant and thousand-grain weight. Results showed that K3 application resulted in significant improvements, especially under stressful conditions. Under irrigation, the plant height of Ghazi-2019 increased by 15% (99 cm), while the thousand-kernel weight of Subhani-2021 increased by 20% (69 g). In TDC, Akbar-19 yields increased by 25% (7.7 g/plant) using K3 compared to K1. Faisalabad-2008 yield increased by 30% under K2 (7.1 g/plant) irrigation. Applying K to wheat under both irrigation and TDS can significantly increase wheat yield in the later stages of growth.
Pesticides and Their Effects on Gut Microbiota: A Comprehensive Review of Environmental and Health Consequences
Authors: Aduljaleel Aat , Aljawhar Nooralhuda , Jassim Sara , Nazar Zeyad
Published: December 2024

An increasing use of pesticides in agriculture is considered as the dangerous hazard to environment, human health, and sustainability. The effects of pesticides on organisms include decline in the amount of phytoplankton and zooplankton, development of resistance in pests and negative impacts on pollinators. These chemical residues too interfere with the biogeochemical cycles, reduce the microbial count in the soil, and are anti-neo plastic and carcinogenic in nature in different species. Concerning human health effects, the exposure to these chemicals cause cancer, deterioration of neurodevelopment, reproductive disorders as well as immune disorders. Besides, the action of pesticides is aimed at destroying both the beneficial bacteria of the gut microbiota, thus causing obesity and diabetes. The measures required for these problems include regulation and farmer awareness and schooling to stop the contamination from piling up in water bodies. Some strategies include microbial degradation, pesticide degradation and improvement of the population of microorganisms in the soil. Organic farming and sound policies are important to maintain and improve the earth’s condition, uphold the companies’ standards set by the legal frameworks, and sustain the quality of life. Therefore, the impacts of pesticides on microbiota and the interactions of hosts and microbes need to be analyzed to devise appropriate solutions. These efforts are very useful for dealing with possible health threats and ensuring environmentally friendly farming.
Diyarbakır bölgesinde subklinik mastitisli keçi sütlerinde mastitis etkenlerinin izolasyonu ve duyarlı antibiyotiklerin belirlenmesi
Authors: Yeşilmen Alp Simten , Özyurtlu Nihat , Altan Feray , Bademkıran Servet , Vural Aydın , Kaplan Bilmez Yasemin
Published: December 2024

Keçi sütünün, laktoz intoleransı olan insanlarda inek sütüne alternatif olmasından dolayı son yıllarda dünya genelinde tüketiminde artışı görülmektedir. Keçi mastitisi, süt kalitesini olumsuz etkilemekte ve süt veriminde azalmalara yol açmaktadır. Bu nedenle mastitis patojenlerinin belirlenmesi enfeksiyonun önlenmesi açısından önemlidir. Bu çalışmanın amacı Diyarbakır ve ilçelerinde bulunan keçilerde, subklinik mastitis etkenlerinin izolasyonu ve identifikasyonu ile bunlara etkili antibiyotiklerin minimal inhibitör konsantrasyonu (MİK) yöntemi ile belirlenmesidir. Bu amaçla toplam 358 adet keçi süt örneğine California Mastitis Testi (CMT) ile mastitis yönünden bakıldı. CMT (+2,+3) pozitif olan toplam 106 süt örneğinin mikrobiyoloji incelemesinde 79’undan (%74.5) bakteri izole edilirken, 27’sinden (%25.5) herhangi bir üreme gözlenmedi. Üreme olan süt örneklerinin 30’undan (%37.97) Staphylococcus aureus ve 26’sından (%32.91) Koagülaz-negatif Staphylococcus (KNS), 3’ünden (%3.80) Streptococcus agalactiae, 1’inden (%1.27) Enterococcus spp., 18’inden (%22.78) Escherichia coli ve 1’inden de (%1.27) Acitenobacter spp. izole ve identifiye edildi. KNS pozitif olan bakterilerin orantısal olarak dağılımı %20.25 Staphylococcus xylosus, %5.06 Staphylococcus warneri, %2.53 Staphylococcus lugdunensis, %1.27 Staphylococcus capitis, %2.53 Staphylococcus chromogenes ve %1.27 Staphylococcus hominis olarak identifiye edildi. Çalışmada izole ve identifiye edilen bu bakterilere karşı yapılan MİK sonuçlarına göre siprofloksasin, tigesiklin, benzilpenisilin, oksasilin ve seftazidimin mastitis tedavisinde etkili olabileceği belirlendi.
Çevre Teknolojileri ve Yenilenebilir Enerji Tüketiminin Karbondioksit Emisyonu İle İlişkisi: Türkiye Örneği
Authors: Eryer Ayşe
Published: December 2024

Çevresel kirlilik, doğadaki bütün canlıların hayatını olumsuz bir şekilde etkileyen küresel bir problem olarak karşımıza çıkmaktadır. Özellikle doğada yenilenemeyen enerji kaynaklarından biri olan fosil yakıtların kullanılması, karbondioksit emisyonunun ortaya çıkardığı çevresel kirlilik yoluyla toplum sağlığını olumsuz bir şekilde etkilemekte, yaşam kalitesini düşürmekte ve küresel ısınmaya sebebiyet vermektedir. Yenilenebilir enerji kaynaklarının ve çevre teknolojilerinin kullanımının artması çevresel kirlilik ile mücadele etmede önem teşkil etmektedir. Bu kapsamda çalışmada Türkiye için çevre teknolojileri- yenilenebilir enerji tüketimi ve karbondioksit emisyonu ilişkisi 1990-2020 dönemi için incelenmiştir. ARDL sınır testi ve FMOLS tekniğinden yararlanılmıştır. ARDL analizi sonuçlarına göre, hem kısa hem de uzun dönemde çevre teknolojileri ve yenilenebilir enerji tüketimindeki artış karbondioksit emisyonunu azaltmakta iktisadi büyümedeki artışlar ise karbondioksit emisyonunu artırmaktadır. FMOLS bulgularında ise benzer sonuçların elde edildiği görülmektedir. Hem yenilenebilir enerji tüketimi hem de çevre teknolojileri kullanımı karbon emisyonunu azaltmada önemli rol oynamaktadır.
Sağlık Sistemlerine Güvensizliğin Sağlık Hizmeti Talep Erteleme Davranışına Etkisi
Authors: Çiftçi Kıraç Fatma
Published: December 2024

Çalışmanın amacı sağlık sistemlerine duyulan güvensizliğin sağlık hizmeti talep erteleme davranışına etkisini incelemektir. Araştırmanın evreni Kahramanmaraş ilinde yaşayan 18 yaş ve üzeri bireylerdir. Araştırma kapsamında 384 kişiye ulaşılmıştır. Çalışmada Sağlık Sistemlerine Güvensizlik Ölçeği ve Sağlık Hizmeti Talep Erteleme Davranışı Ölçeği kullanılmıştır. Araştırmadan elde edilen bulgulara göre 18-24 yaş aralığındaki katılımcıların sağlık sistemlerine güvensizlik ortalamaları 35-44 yaş ile 45-54 yaş aralığındaki katılımcılara göre daha yüksek tespit edilmiştir. Bekâr bireylerin sağlık hizmeti talep erteleme davranışı ortalaması evli olanlara göre daha yüksektir. Araştırma bulgularına göre lise mezunlarının sağlık hizmeti talep erteleme davranışı ortalaması üniversite mezunlarına göre daha düşük çıkmıştır. Araştırma sonuçlarına göre, sağlık sistemlerine güvensizlik kendi kendine/ bireysel çare arama davranışını pozitif yönde etkilemektedir. Sağlık sistemlerine güvensizlik kaçınma davranışını ve harekete geçmeme davranışını pozitif yönde etkilemektedir. Sağlık sistemlerine güvensizlik sağlık hizmeti talep erteleme davranışını pozitif yönde etkilemektedir.
Conceptual Recapture of Aamra [Mangifera indica Linn.]
Authors:   Assistant professor, Dravyaguna Department, Government Ayurveda College, Jaipur, Rajasthan, Goyal Swati
Published: December 2024

Aim- To collect and comprehensively review information available regarding the medicinal use of Amra.
Background- Amra [Mangifera indica Linn.] has been used in traditional medicine for the treatment of
different disease. It contains tannins, pyrogallotannins, mangiferin and also contains vitamin A and C. It
shows Anticancer, Anti-diabetic, Anti-inflammatory, laxative action. In various nighantus properties
of amra and its different part have been explained. Though there are few review articles available on this
plant but no review has comprehensively covered all aspects of Amra.
Materials And Methods- This review is in a narrative format and done from literature and publications
relevant to Amra that were identified through a systematic search of major computerized medical databases.
Review Results- Amra [Mangifera indica Linn.], was reviewed from all samhitas and Nighantu’s and from
more than 55 research articles for medicinal uses and other important aspects.
Conclusion- Amra is concluded to have more than 20 Samhita based indications Rakta-rodhaka, Vranaropaka, Stambhana, Garbhashay-ashothahara (Bark); Rakta-rodhaka, Vrana-ropaka, Chhardi-nigrahana
(Leaf); Vrana-ropaka, Mootra-sangrahaniya, Stambhana (Flower); Rakta-rodhaka, Stambhana, Krimi-ghna,
Vrana-ropaka Garbhashaya-shothahara (Seed kernel); Snehana, Anulomana, Saraka, Balya, Varnya,
Brinhana, Vrishya, Hridya, Shonita-sthapana (Ripe fruit); Daha-prashamana (Unripe fruit- Roasted);
Rochana, Deepana, Pachana, Raktapitta- prakopaka (Unripe fruit Unroasted). Amra also possesses anticancer, anti-diabetic, anti-inflammatory properties, hepatoprotective, anti-hemorrhagic, anti-tetanus,
analgesics and antipyretic, kidney damage, anti-ulcer, lipid profile, anti-bone-resorption, anti-diarrheal, antibacterial, anti-fungal, anti-viral, anti-amoebic, anthelmintic, anti-malarial, radio-protective,
immunomodulation, cardio-protective, osteoporosis prevention, recognition of memory, broncho-dilatory
and laxative effects.
Developing the Cross-Cultural Understanding Course Materials for the English Major Students
Authors:   English Letters Study Program, FIB, Universitas Khairun, Indonesia, Hasan Nurprihatina , Andriani Andriani ,   English Letters Study Program, FIB, Universitas Khairun, Indonesia, Majid Bakhtiar ,   English Letters Study Program, FIB, Universitas Khairun, Indonesia, Sutaryo Sutaryo ,   English Language Education Study Program, FKIP, Universitas Khairun, Indonesia
Published: December 2024

Cross-Cultural Understanding (CCU) is one of the compulsory courses required of all six-semester students at the English Literature Study Program of Universitas Khairun. This course provides the students with an awareness of cross-cultural concepts. The problem is that the teaching and learning process of the CCU course in the English Literature Study Program has not been optimal in recent years. One of the reasons is a lack of teaching material to meet learning objectives. This research aims to create a technology-based CCU textbook that contains appropriate teaching materials for students. It is intended that the contents in the CCU textbook to be developed align with the curriculum and Semester Learning Plan (SLP) of the CCU course. Preliminary research as part of three phases of development research design was carried out. A need analysis was conducted to identify students' needs for teaching materials, learning methods, and assessment. A need analysis was conducted with questionnaires via Google form to collect data, involving 43 six-semester students at the English Literature Study Program of Universitas Khairun. The data collected were analyzed using descriptive statistics. It was found that more than 97% of 43 students involved in the study strongly agreed and agreed that a technology-based textbook for the CCU course should be made available. In addition, the textbook of the CCU course should contain materials from online articles, YouTube videos, and links to online English newspapers as well as Indonesian online publications. It was also found that the learning activities reflected in the CCU course should include a discussion, a lecturer explanation, group presentations, individual assignment activities, and group assignment activities. Students' proficiency in the CCU course can be assessed using a variety of methods, including paper writing, projects, and exams.
The Concept of Punishment against Perpetrators of Narcotics Offenses in Article 111 Paragraph (1) And Article 112 Paragraph (2) Of the Narcotics Law
Authors:   Master of Law, Faculty of Law, University Pembangunan Nasional “Veteran” Jakarta, Achnuphi Muhamad Nur Ajie Arie , Wahyudi Slamet Tri ,   Master of Law, Faculty of Law, University Pembangunan Nasional “Veteran” Jakarta, Supardi Supardi ,   Master of Law, Faculty of Law, University Pembangunan Nasional “Veteran” Jakarta
Published: December 2024

This study aims to determine the legal consequences of decisions on narcotics criminal cases that deviate from the provisions of the general minimum special criminal law based on sufficient consideration by the Panel of Judges and the ideal concept of the Supreme Court Circular Letter Number 3 of 2015 concerning the Implementation of the Formulation of the Results of the Supreme Court Chamber Plenary Meeting in 2015 as a Guideline for the Implementation of Duties for the Court in narcotics criminal cases class I. The type of research in this study is normative juridical supported by interviews with informants. The results of the study in this discussion are that the legal consequences of a narcotics criminal case decision deviating from the provisions of the special minimum general criminal law based on sufficient consideration by the Panel of Judges are decisions that are contrary to the principle of legality and cause disparities in judges' decisions for other cases that are identical to legal facts and conflicts of interest between the Public Prosecutor and the Panel of Judges in the trial.
12ª Conferência da Rede Lusófona de Morfologia Urbana, PNUM 2024
Authors: Correia Jorge
Published: December 2024

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“De que margem você vem?” O 12º PNUM às margens do Guamá
Authors: Caser Spolaor Silvia
Published: December 2024

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Análise dos discursos dos políticos do estado do Amazonas sobre os incentivos fiscais concedidos à Zona Franca de Manaus
Authors:   , Silva José Assef da
Published: December 2024

Este estudo teve o objetivo de analisar o conteúdo dos discursos políticos dos deputados do Estado do Amazonas, como argumentos retóricos, relacionados à Zona Franca de Manaus. Os discursos foram coletados por meio de notas taquigráficas disponíveis no site da Câmara dos Deputados, considerando o período de 2013 a 2023, abrangendo quatro presidentes, legislativos e vieses políticos diferenciados de discursos lidos na sessão plenária, disponíveis para o público. A coleta seguiu os seguintes termos e expressões chaves, tais como: política fiscal, incentivos fiscais, Zona Franca, Amazonas, desoneração, Região Norte, benefícios tributários, entre outros termos relevantes para a pesquisa. A pesquisa foi realizada por meio da investigação indireta, onde o pesquisador colhe as informações sem interferir na produção dos dados extraídos, sendo feita a análise dos discursos coletados (conteúdo), com base na leitura de cada frase e parágrafo, e ainda se utilizando das estratégias de retóricas por meio de Aristóteles: Ethos, Logos e Pathos. Nesse sentido, o estudo visou ampliar a compreensão da evolução política e acompanhar os discursos políticos, visando entender as dinâmicas da manutenção do poder e a legitimação dos incentivos concedidos a Zona Franca de Manaus. Em atenção aos discursos dos políticos da Região Norte, existe uma lacuna quanto as alternativas de solução para o problema em questão, haja vista que o Estado é dependente das isenções fiscais do Governo Federal. Um dos principais resultados apresentados, foi o discurso usado de forma eleitoreira, de promoção pessoal para engajamento político. Com a leitura por meio das estratégias retóricas de Aristóteles, foi possível analisar que os discursos tiveram um apelo forte (Páthos), com o sentido de comover o seu público alvo e despertar empatia para quem ouve. Nesse sentido, a pesquisa contribuiu para compreensão da evolução política do Estado do Amazonas, mais especificamente sobre a Zona Franca de Manaus, ampliando a visão sobre as dinâmicas da manutenção do poder e a legitimação dos incentivos fiscais concedidos à região. Além disso, demonstrou-se que os conteúdos dos discursos empregados pelos políticos são repetitivos, independentemente da orientação política, e sem uma atuação mais incisiva, sendo em muitos dos casos para promoção pessoal, apesar de serem usados argumentos sólidos e sustentáveis. Palavras-chave: zona franca de manaus; discurso político; estratégias retóricas; amossy
Oracle APEX for Global Audience: Globalization Methods, Insights and Comparison with Google Translate
Authors:   USA, Syed Ashraf
Published: December 2024

Oracle Application Express (APEX) offers developers a powerful platform for creating applications that meet diverse linguistic requirements. This article
serves as a comprehensive guide to developing a multi-language application on the APEX platform catering to a global audience. It discusses methodologies,
techniques, and strategies for globalizing the application to support multiple languages in APEX. Furthermore, it emphasizes the advantages of using
APEX's built-in features over-relying on a third-party tool, Google Translate.
Sunflower productivity formation in the northeastern part of Ukraine
Authors: Bondarets R. S. , Vereshchahin I. V.
Published: December 2024

Purpose. To determine the efficiency of sunflower (Helianthus annuus) cultivation in the northeastern regions of Ukraine.
Methods. Field studies were conducted in 2020–2024 in the Left-Bank Forest Steppe of Ukraine, at the border of two soil-climatic zones: the Forest Steppe and Polissia.
Results. The average yield indicators of sunflower in the northeastern regions of Ukraine show that this crop is steadily gaining popularity among producers. On average, across the three regions, the annual crop yield exceeds the indicators obtained across the country. In particular, in 2020, a yield increase of 0.73 t/ha was obtained, in 2021, a yield increase of 0.30 t/ha, and in 2022, a yield increase of 0.25 t/ha was obtained. Additionally, in 2022, with an average sunflower seed yield in Ukraine of 2.16 t/ha, Sumy region achieved a yield of 2.62 t/ha, Kharkiv region – 2.29 t/ha, and Chernihiv region – 2.32 t/ha. Conversely, the data of 2023 showed that cultivation of sunflower in the northeastern region of Ukraine requires careful consideration, as the average yield in Ukraine in this year was 2.45 t/ha. Only Chernihiv region achieved a yield of 3.16 t/ha, while Sumy and Kharkiv regions obtained 2.38 t/ha and 2.18 t/ha, respectively. Therefore, the average yield of the crop in these three regions was 0.08 t/ha lower than the national average.
Conclusions. In Sumy, Kharkiv, and Chernihiv regions, sunflower cultivation has reached a large industrial scale, which requires the development of efficient cultivation technology. Over the past four years, the harvested area has averaged 17.7%, and production volume averaged 19.8% of the total sunflower cultivation in Ukraine. At the same time, the average seed yield of the crop was 2.54 t/ha, while in the period 2020–2024, the average yield was only 2.21 t/ha.
Identificação de fatores de risco para o desenvolvimento de síndrome metabólica em estudantes de Instituição de Ensino Superior do Espírito Santo
Authors: De Souza Luana Barbieri , Do Norte Vitória Fial , Andrade de Souza Marco Antônio
Published: December 2024

A Síndrome Metabólica (SM) é um conjunto de alterações que aumentam o risco de doenças cardiovasculares e metabólicas. Segundo alguns estudos, atualmente, a frequência de SM encontrada em estudantes universitários é consideravelmente baixa, entretanto, elevações nos fatores de risco associados à SM têm sido cada vez mais frequentes nesta população. Este estudo investigou a frequência de fatores de risco para SM em estudantes de uma Instituição de Ensino Superior do estado do Espírito Santo, com base em dados antropométricos e bioquímicos. Foi realizada uma pesquisa transversal analítica, que envolveu 57 estudantes de cursos variados, com idades entre 18 e 37 anos. Os dados pessoais e sobre o estilo de vida foram obtidos por um formulário online e a coleta de material biológico foi realizada na própria instituição. Os resultados indicaram que 10,5% dos universitários já possuem o diagnóstico para a síndrome metabólica, sugerindo um percentual ligeiramente elevado. Obteve-se ainda uma alta incidência nas elevações da pressão arterial (33,3%), colesterol total (40,3%) e circunferência abdominal (14%), em conjunto com a diminuição do HDL- colesterol (15,8%), demonstrando a necessidade de ações preventivas para evitar o desenvolvimento de complicações metabólicas e cardiovasculares em uma fase mais avançada da vida, bem como a implantação de medidas que auxiliem no seu diagnóstico precoce. Diante desse cenário, é fundamental a criação de programas que incentivem a prática de atividade física e promovam a adoção de hábitos alimentares saudáveis.
Hanseníase: Aspectos Imunológicos e Métodos Diagnósticos - uma revisão
Authors: Belo do Prado Carla , Dayrell França Flávia
Published: December 2024

A hanseníase é uma doença infecciosa, transmissível, crônica, causada pelo Mycobacterium leprae. Aspectos genéticos, imunológicos e ambientais determinam a suscetibilidade individual ao bacilo e explicam a progressão e/ou regressão da doença. O objetivo do trabalho foi avaliar e compreender os aspectos imunológicos da hanseníase e como eles podem influenciar no diagnóstico. Foram selecionados 6 artigos referentes às características imunológicas da hanseníase e 4 artigos relacionados aos métodos diagnósticos. Os resultados demonstram que a expressão aumentada do receptor “Toll Like 4” em neutrófilos é um biomarcador universal. A suscetibilidade a polos da hanseníase foi demonstrada pelo polimorfismo de nucleotídeo único (SNP) na região promotora do DC-SIGN CD209, Gene IL-17A e do Receptor de vitamina D (VDR) nas regiões FokI, TaqI e ApaI. Houve aumento na expressão do fator de transcrição FOXP3 em pacientes multibacilares e durante as reações tipo 1. Quanto ao diagnóstico por detecção de anticorpos, o conjugado NDO-LID apresentou maior sensibilidade que NDO-BSA e LID-1 separadamente. Já o teste rápido ML-Flow teve alto nível de positividade, mas a maioria dos paucibacilares não desenvolvem anticorpos detectáveis, não sendo diagnosticados por esse método. Quanto à investigação do DNA do M. leprae, o ISSR-PCR demonstrou ser um método mais eficaz que RLEP-PCR e baciloscopia. Assim, pode-se concluir que o sistema imunológico está intimamente relacionado com o desenvolvimento da hanseníase. A análise dos métodos deixa claro que o uso de antígenos para detecção de anticorpos e a análise do DNA do M. leprae são eficazes e rápidos, quando comparados com a baciloscopia.
Crystalloid fluid choices and their impact on acute kidney injury and other outcomes in pediatric sepsis a prospective study in Ecuador
Authors: Rodríguez-Portelles Alfredo Carlos , Céspedes Rómulo Arianna Maité , Jaimes Isaura , Vivas Fernández Marielena , Guachichulca Romer , Campos-Miño Santiago , Yeroví Santos Rocío
Published: December 2024

Introduction: Sepsis and septic shock are significant causes of morbidity and mortality in pediatric patients, with fluid resuscitation being a critical intervention. This study compares the effects of 0.9% saline solution and Ringer Lactate on acute kidney injury (AKI), metabolic acidosis, and overall outcomes in pediatric sepsis. Objective: To evaluate the association between fluid type and the incidence of AKI, metabolic acidosis, and mortality in pediatric patients with sepsis or septic shock.
Methods: A prospective observational study was conducted from January to November 2023 at Hospital Padre Carollo "Un Canto a la Vida" in Quito, Ecuador. Thirty-five children aged 1 month to 179 months with sepsis or septic shock were included. Patients received either 0.9% saline or Ringer Lactate based on clinician judgment. Primary outcomes were the incidence of AKI and metabolic acidosis. Secondary outcomes included mortality and length of stay. Logistic regressions were performed to assess outcomes.
Results: The incidence of AKI was significantly higher in the saline group (30%) compared to the Ringer Lactate group (13.3%) (p=0.045). Metabolic acidosis was also more common in the saline group (25% vs. 6.7%; p=0.037). Mortality did not differ significantly between groups (5% in saline vs. 0% in Ringer Lactate; p=0.325). The median ICU length of stay was 12 days for saline and 10 days for Ringer Lactate (p=0.356). Conclusions: Ringer Lactate is associated with a lower incidence of AKI and metabolic acidosis compared to 0.9% saline in pediatric sepsis patients. These findings suggest that balanced crystalloids may offer safer outcomes for fluid resuscitation in this population.
Pengaruh Premi Asuransi, Claim dan Recovery Terhadap Kualitas Layanan Melalui Kepuasan Pengguna Asuransi Kendaraan Bermotor di Kota Makassar
Authors: Herlina  , Ramlawati  , Suriyanti
Published: December 2024

Insurance is a financial means in economic guarantees, both in facing risks to owned assets. This study aims to analyze the direct and indirect effects of insurance premiums, claims and recovery on service quality through motor vehicle insurance user satisfaction. This study uses a quantitative method approach. The data collection technique (instrument) used is a survey and questionnaire. The population and sample are purposive motor vehicle insurance users totaling 126 respondents. Data analysis uses SEM-PLS analysis with outer and inner models. The results of the study found that insurance premiums and claims directly have a positive and significant effect on the quality of motor vehicle insurance services. Recovery has a positive and insignificant effect on the quality of motor vehicle insurance services. Insurance premiums, claims and recovery directly have a positive and significant effect on the satisfaction of motor vehicle insurance users. User satisfaction directly has a positive and significant effect on the quality of motor vehicle insurance services. Insurance premiums, claims and recovery directly have a positive and significant effect on service quality through motor vehicle insurance user satisfaction in Makassar City.
Analisis Pengaruh Tingkat Inflasi dan Suku Bunga Terhadap Kinerja Keuangan Perusahaan Dengan Nilai Tukar Sebagai Moderasi
Authors: Hilyati Zikriani  , Nur Fatwa  , Ramla Ilham Darise  , Septiana Na'afi  , Dwi Anna Kristanti
Published: December 2024

Ukuran kinerja dalam industri perbankan memiliki peran yang sangat krusial karena kinerja bank merupakan keseluruhan dari gambaran kegiatan dan operasional baik dari segi keuangan, sumber daya manusia, pemasaran, penghimpunan dana maupun pembiayaan dalam satu periode tertentu. Penelitian ini menggunakan kuantitatif. Populasi yang digunakan dalam penelitian ini adalah seluruh perusahaan perbankan yang terdaftar di Bursa Efek Indonesia selama tahun 2020 hingga 2023 dan Sampel yang digunakan dalam penelitian ini adalah perusahaan perbankan yang terdaftar di Bursa Efek Indonesia dengan menggunakan pendekatan purposive sampling, yaitu pemilihan sekelompok subyek didasarkan atas ciri-ciri atau sifat-sifat tertentu. Hasil penelitian telah menemukan bahwa inflasi dan suku bunga berpengaruh terhadap kinerja perusahaan. Nilai tukar sebagai variabel moderasi mampu memoderasi pengaruh tingkat inflasi dan suku bunga terhadap kinerja perusahaan.
A Group of Phaselis Type 3 Amphorae by the Base of the Phaselis Central Tower: A New Pottery Dumpster (Bothros) and Amphora Production Area
Authors: Orhan Uğurcan
Published: December 2024

In 2021, seven test trenches were excavated by the base of the Central Tower using random sampling techniques. The purpose of the excavation was to assess the potential for conservation and landscaping projects planned for the area north of the Phaselis city center. Although the trenches are independent from each other, they were determined systematically. The finds indicate the production of ceramics and
amphorae. In relation to this production organization, numerous fragments of broken or incomplete amphorae were also found in the area. Their discovery sheds light on the production organization of Phaselis. Among them are locally produced Phaselis amphorae, which have recently been introduced to the literature, as well as imported and imitation amphorae. New types of Phaselis amphorae were also identified based on their morphological characteristics. This study focuses on the forms belonging to Type 3 Phaselis amphorae, as faulty examples of this type were identified. The studies conducted in these test trenches revealed a new ceramic dumpster (bothros) and amphora production area in addition to the Hellenistic Temple Area. The production of ceramics and amphorae was carried out in different areas in a process-dependent manner, as shown chronologically. The aim is to reveal the production and consumption organization in the area from the fifth century BC to the third century BC. A new ceramic dumpsite and amphora production area are introduced to the literature.