bluuebunny/crossref_metadata_2025 huggingface dataset:
Knowledge and Scholarly Authority in Al-Ghazali’s Philosophy: A Study of Fatihatul ‘Ulum
Authors: Suwarno M. Hadi , Albab Hayyan Ahmad Ulul
Published: February 2025

Islamic education is a place to form humans who can carry out their duties as caliphs on earth. Knowledge of the concepts of science and scholars is needed to understand and develop science and scholars in Islamic teachings combined with the philosophy of Islamic education. This concept is the basis for understanding the philosophy of Islamic education. The two have a close relationship. The purpose of this research is to describe the concept of science according to Imam Al-Ghazali and to find out the role of ulama' according to Imam Al-Ghazali in the book of Fatihatul 'Ulum. This research method uses a literature review focused on the book of Fatihah al-Ulum. The data collection technique uses the documentation method related to the book of Fatihah al-Ulum and other works that are still one theme of discussion. Analysis of this literature study uses content analysis by looking at the validity of the original data and explaining it again by comparing other sources. First, researchers found knowledge as the main foundation of a person so that he can know Allah SWT. Studying science is considered something with good intentions by seeking the pleasure of Allah SWT. After knowledge is obtained, a person will become more moral and can practice religious and general knowledge with a heart that is always linked to Allah SWT. Secondly, being an ulama' is a big responsibility because he is the heir of the Prophet SAW. Ulama' must link their hearts to seek the pleasure of Allah, leave the affairs or desires of the world, and teach all the knowledge they have so that their students can take the path of Allah's pleasure.
Situación socioeconómica y territorialidad en las familias: Impacto en la educación
Authors: Bonilla Quilligana Cristina Aracelly , Pilatasig Lasluisa Olga Mercedes , Jiménez Guarnizo Juan Carlos , Jiménez Mendieta Rosario Elizabeth , Cachipuendo Pineida Liliana Patricia
Published: February 2025

La investigación presenta un enfoque cuantitativo, utilizando un instrumento validado para medir las variables de estudio relacionadas con la situación socioeconómica y la territorialidad en las familias, con el fin de asegurar la confiabilidad de los resultados. Se aplicó el “Cuestionario de Desarrollo Local mención: Planificación, Desarrollo y Ordenamiento Territorial” diseñado por Huilca (2022), que se basa en un análisis económico y territorial. La validez y confiabilidad del instrumento han sido evaluadas mediante diversos métodos, garantizando la robustez de los resultados obtenidos. El cuestionario fue administrado a 50 familias de la parroquia Cunchibamba, barrio Montalvo, con participación voluntaria. Los hallazgos indican que la situación socioeconómica de la comunidad se encuentra en un nivel de pobreza, ya que el 50% de las familias encuestadas se identificaron como "más o menos pobres", principalmente debido a la falta de empleo estable. Además, se identificaron políticas y leyes que regulan a los Gobiernos Autónomos Descentralizados (GAD) Parroquiales, las cuales buscan promover proyectos que fortalezcan la economía en las zonas rurales, destacando la relación entre la territorialidad y la educación en el contexto socioeconómico actual.
POLÍTICAS PÚBLICAS, EDUCAÇÃO E TECNOLOGIA: A LEI Nº 15.100/2025 COMO MARCO REGULATÓRIO NA EDUCAÇÃO BÁSICA
Authors: Vianna Pedro Henrique Farias , Santos Silvana Maria Aparecida Viana , Veiga Alcione Maria de Souza , Limas Ariana Geraldo , Machado Ingrid Laila Ferreira , Fernandes Hodac Rosendo , Cunha Erli da Conceição Belicio , Rodrigues Alini Belicio de Souza , Neiva Clessia dos Santos Oliveira , Costa Sheila Sousa da , Araújo Marcos Paulo Parente , Silva Huarlison de Souza , Parente Maíra Santiago Pires , Bezerra Thaynara de Moura , Cardoso Raimunda Neia Mendes
Published: February 2025

O avanço da tecnologia tem impactado significativamente a educação, tornando essencial a regulamentação do uso de dispositivos eletrônicos no ambiente escolar. Nesse contexto, a Lei nº 15.100/2025 estabelece diretrizes para a utilização de aparelhos eletrônicos portáteis pessoais na educação básica, com o objetivo de preservar a saúde mental e o bem-estar dos estudantes. Este estudo busca analisar os impactos dessa legislação no processo educacional, investigando sua influência na aprendizagem, na interação social e na saúde psíquica dos alunos. A pesquisa foi conduzida por meio de uma revisão da literatura, baseada na análise de 10 artigos científicos e da referida legislação, obtidos em bases como Google Acadêmico e SciELO. Os dados foram examinados de forma qualitativa, identificando desafios e oportunidades da regulamentação. Os resultados indicam que a lei visa equilibrar a inserção da tecnologia no ensino, restringindo seu uso irrestrito, mas permitindo sua aplicação pedagógica e garantindo a acessibilidade e a inclusão. Além disso, destaca-se a necessidade de estratégias institucionais para lidar com o impacto psicológico do uso excessivo de telas. Conclui-se que a legislação representa um avanço na governança educacional, porém, sua eficácia dependerá da adesão e adaptação das escolas às diretrizes estabelecidas. Recomenda-se a realização de estudos empíricos para avaliar os efeitos práticos da norma e possíveis aprimoramentos.
A DEPRESSÃO PÓS-PARTO EM ADOLESCENTES COMO UM PROBLEMA DE SAÚDE PÚBLICA: UMA REVISÃO DE LITERATURA
Authors: Alves Débora Larissa Rufino , Santos Cayo Dos , Melo Claudio André Gomes Moura de , Lopes Romário Mascena Amorim , Lira Elvis Vinicius Silva , Lima Kaique Lopes de
Published: February 2025

ABSTRACT: Teenage mothers have to deal with the challenges of developmental tasks typical of adolescence, but also with the stressors associated with pregnancy and motherhood. Thus, some stressors are experienced with greater intensity and can result in greater psychological distress for teenage mothers (PACHECO, 2003). The prevalence of postpartum depression (PPD) is, on average, 10% to 15%, with important cultural variations in risk factors. Recent studies indicate rates of 3.6% in Germany to 34.7% in South Africa. (FONSECA, 2010) In Brazil, a prevalence of 12% was found in Rio de Janeiro, 13.4% in Brasília, 20.7% in Porto Alegre, 26.9% in Belo Horizonte and 7.2% in Recife (FIGUEIRA, 2010). METHODOLOGY: The method used for research was the literature review, in the following databases: MEDLINE (Medical Literature Analysis and Retrieval System Online) and LILACS (Latin American Caribbean Literature in Health Sciences), with the following descriptors: Postpartum depression, Adolescent pregnancy, women’s health, medicine. RESULTS AND DISCUSSION: For better clarification, guiding questions were answered in light of the scientific literature that corroborated the affirmation of postpartum depression in adolescence as a public health problem. CONCLUSION: The relevance of the topic of postpartum depression in adolescence is evident, since this population is still completing its physical and psychological growth and development, being exposed to the difficult task of gestation, and it is essential to carry out further studies on this topic to improve the quality of care provided to women in their different stages of development. KEYWORDS: Postpartum depression; Adolescent pregnancy; Women’s health; Medicine.
Neuroplasticidade na Terceira Idade: Estratégias para Prevenção do Declínio Cognitivo
Authors: Lima Prado José Walter , Klug Larissa , Luciano Carolina Ferreira , Correia Nunes Márcia Luana , Paulino Suzanna Tavares , Sato Rafael Yuri , Praciano Costa Marine , De Andrade Tiago Leal Dutra , Mendes Brena Magalhães , Loiola Neto Isac Rodrigues , Colla Frigeri Natasha , De Oliveira Gabriele Moura
Published: February 2025

A neuroplasticidade na terceira idade tem ganhado destaque como uma abordagem promissora na prevenção do declínio cognitivo, especialmente diante do aumento da população idosa e da prevalência de demências. Este estudo teve como objetivo analisar as estratégias de estimulação da neuroplasticidade na terceira idade e seu impacto na prevenção do declínio cognitivo, destacando as intervenções mais eficazes e os mecanismos neurofisiológicos envolvidos. A metodologia baseou-se em uma revisão integrativa da literatura, abrangendo estudos publicados entre 2008 e 2024 em bases de dados como PubMed/MEDLINE, SciELO, Lilacs e Scopus. Os principais descritores utilizados incluíram “neuroplasticidade”, “terceira idade”, “declínio cognitivo” e “prevenção de demência”. Os resultados indicaram que intervenções como treinamento cognitivo complexo, exercício físico e estimulação cerebral não invasiva promovem mudanças significativas na conectividade cerebral e na integridade da substância branca, potencializando a neuroplasticidade e mitigando perdas cognitivas relacionadas ao envelhecimento. Além disso, a interação entre plasticidade sináptica, estrutural e funcional foi identificada como essencial para a manutenção das funções cognitivas. Conclui-se que abordagens integradas, combinando treinamento cognitivo, exercício físico e suporte social, podem otimizar os desfechos cognitivos e promover um envelhecimento saudável. No entanto, são necessários estudos longitudinais para avaliar o impacto a longo prazo dessas intervenções e aprimorar as práticas clínicas na promoção da neuroplasticidade em idosos.
Fatores prognósticos e cuidados pós-ressuscitação na parada cardiorrespiratória: da reanimação à recuperação
Authors: Almeida Gustavo de Sousa , Santos Wollax christmans Alves dos , Júnior Nilton Carvalho Pereira , Souza Marcus Vinícius Stevanin de , Lima Christiane Thiersch de , Zappelini Luiz Vicente Antunes , Ono Ludgero Keiji Sardi , Arantes Ana Clara , Cintra Filipe Tadeu Pereira , Forti Rumeningg Abreu , Felgueira Maria Caroline Turate , Thoma Amanda , Quessada Murilo Alencar , Souza Nicole Gundim de
Published: February 2025

A dermatite atópica (DA) é uma doença inflamatória crônica da pele, comum na infância, caracterizada por lesões eczematosas, prurido intenso e comprometimento da barreira cutânea. Este estudo revisa o papel dos emolientes e das barreiras cutâneas no manejo da DA infantil, com foco na identificação de estratégias que influenciam os desfechos clínicos. A metodologia baseia-se em uma revisão narrativa da literatura, com consulta às bases de dados PubMed, SciELO e Google Acadêmico, utilizando as palavras-chave: “Dermatite Atópica”; “Emolientes”; “Higiene da Pele” e “Gerenciamento Clínico”. A análise aborda os mecanismos fisiopatológicos da DA, como disfunção da barreira cutânea e inflamação, e revisa os principais estudos que investigam fatores como idade, gravidade da doença e adesão ao tratamento. Os resultados destacam que o uso regular de emolientes e a aplicação de barreiras cutâneas, como ceramidas e ácidos graxos, são cruciais para restaurar a função da barreira cutânea e reduzir a inflamação. Conclui-se que, apesar dos avanços no manejo da DA, persistem desafios clínicos significativos, como a variabilidade na resposta aos tratamentos e a necessidade de abordagens personalizadas. Estratégias como a educação dos cuidadores e a implementação de protocolos padronizados são essenciais para melhorar a qualidade de vida das crianças com DA e suas famílias.
Global Energy Transition Negotiations
Authors:   Millersville University, Huntingdon Valley, Pennsylvania, USA, Kline Samantha
Published: February 2025

The World Wildlife Fund’s (WWF) Global Energy Policy Framework offers a comprehensive approach to addressing the challenges of global energy production and consumption in the context of climate change, biodiversity loss, and social equity. This essay analyzes WWF’s framework, which advocates for the decarbonization of the global energy system, the rapid transition to renewable energy sources, the promotion of energy efficiency, and the protection of ecosystems. It examines the strengths and potential challenges of the framework, particularly its implementation in diverse political and economic contexts. It assesses their feasibility in various national settings. The conclusion emphasizes the framework’s potential to guide the transition to a sustainable, low-carbon, and inclusive global energy system. Ultimately, WWF’s policy framework provides a holistic, integrated approach that aligns climate action with conservation goals, offering a valuable path for achieving a sustainable energy future.
La Chanson d’actualité, de Louis XII à Henri IV
Authors: Millet Olivier , Tacaille Alice , Vignes Jean
Published: February 2025

Plus d’un siècle après les travaux pionniers d’Auguste Le Roux de Lincy et d’Émile Picot sur les « chants historiques », au moment où les sources premières deviennent plus accessibles, les études littéraires, historiques et musicologiques joignent, dans ce volume, leurs forces pour renouveler le regard sur la chanson dite d’actualité. Dès le début du XVIe siècle, à travers de minces plaquettes gothiques, des soldats, des aventuriers, des clercs, de simples bourgeois témoignent par des chansons des conflits qui les divisent. Textes aux airs bien souvent perdus, inscrits en profondeur dans l’histoire de leur temps, leurs chansons participent à l’œuvre de propagande des parti(e)s en présence au fil des conflits qui agitent le siècle. Elles rassemblent aussi des communautés, notamment dans la commémoration des événements et des figures qu’elles illustrent.

Les contributions de ce volume se consacrent aux supports et aux sources qui nous donnent accès à ces airs et à ces textes (chansonniers, paroliers, placards, minutes de procès, etc.), et elles en montrent toute la diversité générique et formelle : chansons historiques, chansons spirituelles, chansons à boire… Elles visent à définir la poétique du genre (si genre il y a), sans oublier ce que ces textes nous disent de leur réception et de leur diffusion. L’investigation porte aussi sur le statut de la vérité, sur l’utilisation de la rumeur et d’une rhétorique propagandiste, car les nouvelles véhiculées dans ces chansons, comme dans d’autres textes d’actualité, sont le fait d’auteurs, parfois anonymes, qui peuvent prendre fait et cause pour un parti ou une idée, notamment dans le cadre des guerres de Religion. Le dialogue des différentes disciplines sollicitées aide à cerner les codes qui régissent ces chansons, à dégager leurs spécificités textuelles et musicales, mais aussi à les réinscrire au plus près de leur contexte historique et à saisir leur influence et leurs modalités d’action.
Sedimentación en Canales del Bajo Delta del Paraná
Authors: Sabarots Gerbec Martín , Cortese Julián E.
Published: February 2025

La sedimentación de los cursos que componen la red de canales del Bajo Delta del río Paraná es un fenómeno que afecta las actividades de quienes habitan y trabajan en el Delta. Debido a la falta de tareas de dragado de forma sistemática, resulta cada vez más frecuente la imposibilidad de navegar ciertos cursos ante escenarios de aguas bajas. A partir de información batimétrica, hidrométrica y sedimentológica relevada in situ, se desarrolla un modelo morfodinámico de un curso del Delta para estudiar los principales factores que contribuyen a la acreción de estos canales. Entre los factores a estudiar se encuentran las condiciones de contorno, específicamente los niveles de marea ingresantes por los extremos del canal, la condición hidrológica del río Paraná, las características del sedimento y una aproximación al efecto de la vegetación acuática sobre la rugosidad del canal. Como resultado se busca aportar conocimiento sobre el comportamiento hidro-sedimentológico de la condición batimétrica actual del curso, como así también de las circunstancias hidrodinámicas que propiciaron el desarrollo de la misma.
A Study on the Intervention of Inattentive Behaviors in Children With Moderate Intellectual Disabilities Based on Positive Behavior Support
Authors: Liu Ziai , Li Yixin , Ye Mingyu , Zhang Hanjie
Published: February 2025

This study evaluated the use of Positive Behavior Support (PBS) based on Functional Behavioral Assessment (FBA) to reduce inattentive behaviors in children with moderate intellectual disabilities. Employing a multiple-base-line design, three 15-year-old male students from a special education school in Shandong participated in individualized interventions lasting 9–15 sessions. Strategies included classroom environment adjustments, behavior cues, differential reinforcement, and timely behavioral interruptions. Results showed substantial reductions in inattentive behaviors across all three cas-es, with Case J showing the greatest improvement (from 11.78 to 2.45 in-stances per session), followed by Cases W and G, with decreases of 6.44 and 4.97, respectively. All cases had a Tau effect size of 1.00, reflecting strong intervention effectiveness. Participants also displayed enhanced fo-cus, self-regulation, and quality of life, as reported by teachers and parents. However, limitations such as short intervention durations and limited parent involvement were noted, pointing to the need for extended interventions and stronger home-school partnerships. Overall, PBS proved to be an effective and flexible approach to improving classroom behaviors and social adapt-ability in children with moderate intellectual disabilities.
Application of Data-Driven Prediction and Strategic Optimization in Olympic Medal Distribution
Authors: Zhu Zhaoyu , Shen Jiajin , Yu Minghao , Liang Chengtian
Published: February 2025

The Olympic medal list is an important indicator to assess the competitive strength of countries, and the prediction and analysis of the distribution of the number of medals provide a scientific basis for countries to formulate sports development strategies. This paper takes the 2024 Paris Olympic Games and the previous Olympic Games as the basic data, combines the historical medal data, the distribution of each Olympic Games and the special characteristics of the host country, constructs a number of mathematical models, explores the law of medal distribution, and proposes a strategy to improve the number of medals.The model in this paper is comprehensive, flexible and practical, which provides a new way of thinking for the analysis of medal distribution in the Olympic Games, and also provides data support for the sports development strategy of each country.
Exploring Antitrust Legislation for Data Rights Protection Under the Perspective of New-Quality Productivity
Authors: 贺 德财
Published: February 2025

New-quality productivity is a key driver of China’s modernization and high-quality development, relying on both the activation of data as a new produc-tion factor and the support of technological innovation and fair market com-petition. However, legal shortcomings in data property rights protection and weak innovation incentives hinder the realization of data’s full value. To ad-dress this, the paper proposes a twofold strategy: first, establish a compre-hensive data property rights protection system by clarifying data ownership, usage, and management rights; second, use antitrust law to foster an inno-vationfriendly enforcement model, encouraging continuous high-quality achievements. Integrating data empowerment and innovation incentives ensures a healthy, sustainable development path for the data economy, lay-ing a solid legal and economic foundation for Chinese-style modernization.
The Role of Systematic Taxonomy in Protecting Endangered Animals
Authors: HU Yi
Published: February 2025

With the escalating biodiversity crisis, systematic taxonomy is essential to the protection of endangered species, as it supports accurate species identification, guides conservation priorities, and informs recovery strategies. This paper highlights the critical role of taxonomy in endangered species conservation and addresses challenges such as taxonomic gaps, technical limitations, insufficient data sharing, and the disconnect between research and conservation efforts. Suggested solutions include integrating taxonomy research into decision-making, improving technical capabilities, fostering international collaboration, enhancing public engagement, and diversifying funding sources. Through case studies of China’s endemic species (giant panda, crested ibis, Chinese giant salamander) and successful global initiatives (EDGE project), the paper illustrates practical strategies for advancing conservation. The discussion also explores future opportunities, including artificial intelligence and environmental DNA technologies, to strengthen taxonomy’s impact on conservation. By combining theoretical insights, practical approaches, and graphical data presentation, this paper provides a foundation for innovative biodiversity protection methods.
Comparison of Recovery in Single Layer Vs Double Layer Closure Technique in Patients Undergoing Ileostomy Reversal
Authors: Syed Safiullah  , Ahmed Raza  , Muhammad Zakria
Published: February 2025

Objective: To evaluate the outcomes of recovery based on single-layer versus double-layer suture closure techniques in patients who have undergone ileostomy reversal. Methods: After the ethical approval from the institutional review board, this comparative observational study was conducted at Nishtar Hospital Multan, from 1st September 2023 to 1st March 2024. Through non-probability consecutive sampling, 50 patients above age 18 years, both genders, Patients with ASA class I-III, Patients who are undergoing a temporary ileostomy for any clinical indication, such as colorectal cancer, inflammatory bowel disease, or trauma, and are now candidates for ileostomy reversal were included in the present study. Patients were randomly divided into two groups; Group A single layer suture (n=25) and Group B- double layer suture (n=25). Results: In the present study, the most common type of anastomosis is entero-enteric, and the least was colo-rectal. The mean duration of was significantly greater in group B as compared to group A (19.6±1.9 vs. 30.0±1.8, p<0.0001). Most common complication was wound infection in both study groups. The mean duration of the participants in the hospital is almost similar between the groups (8.4±1.4 and 8.7±0.8; p=0.284). Conclusion: Hence, based on our findings, the single-layer approach while conducting the ileostomy reversal can be beneficial and indeed result in a reduction in time, without any difference in complications. Additionally, it is also easier to train surgical residents in the single-layer techniques, as opposed to the double-layered technique, especially in a teaching institute setting. We recommend the usage of the single-layer method while conducting the ileostomy reversal based on this study.
The Power of Building Teamwork in Business Success
Authors: Ahmed Engy Khamis Abdel Azem
Published: February 2025

Teamwork is an essential component of business performance as it impacts productivity, creativity, management, and organizational outcomes. This study aims at discussing the importance of the concept of teamwork by defining it as well as studying its theoretical and practical aspects in different fields. The study uses online questionnaire whereby independent working professionals in the technology, healthcare, finance and manufacturing industries are expected to provide information on the effects of teamwork to business. The results show that teamwork leads to better goals clarification and communication, leadership support, and cooperation with colleagues which in turn results in higher productivity, lower employee turnover, and company’s financial growth. This study also shows that whereas the variables of the study show that both transformational and servant leadership have a positive effect on teamwork effectiveness laissez faire leadership on the other hand, has little effect on teamwork effectiveness. Also, the correlation matrix reveals a significant relationship between communication effectiveness as well as collaboration and the commitment to a continuous improvement approach. Nevertheless, there are challenges that were observed to impact on the effectiveness of teamwork which includes, lack of communication, unclear objectives and goals and lack of leaders to lead the teams. Long-term benefits are achieved when organizations implement a structured teamwork strategy, performance measurement system, and leadership development. This study adds to the existing body of knowledge dedicated to the field of organizational behavior since it offers evidence of the increasing business outcomes that result from structured teamwork. The study becomes relevant for businesses to focus on the importance of establishing strong and adapted team cultures, improving managerial communication channels and developing leadership skills to stay relevant in the existing and emerging market conditions. Further research should extend years down the line to evaluate the long-term organizational implications of teamwork and should examine the use of technology to bolster teamwork
Effective Pastoral Leadership in Church Growth and Renewal
Authors: Kesumawati Kesumawati , Gultom Joni Manumpak Parulian
Published: February 2025

Pastoral leadership has a crucial role in supporting the growth and renewal of the church. In the modern era, social and technological changes require church leaders to adapt to more innovative strategies that are relevant to the needs of the congregation. Many churches are stagnant due to a lack of visionary, ministry-based leadership. Therefore, this study aims to analyze the characteristics of effective pastoral leadership as well as explore strategies that can be applied to build a dynamic and responsive church to change. This research uses a literature review method with a qualitative approach, analyzing various academic sources such as journals, books, and research reports related to church leadership. Thematic analysis techniques are used to identify patterns in pastoral leadership that have a positive impact on congregational growth and church revitalization. The results of the study show that effective pastoral leadership is characterized by the characteristics of servant leadership, visionary communication, strong spiritual discipline, and the ability to adapt to the times. In addition, strategies such as strengthening small group-based communities, digitizing ministries, and collaborative leadership have proven to be able to increase congregational engagement and strengthen the spiritual foundation of the church.
Cybersecurity in the AI Era Measures Deepfake Threats and Artificial Intelligence-Based Attacks
Authors: Ratnawita Ratnawita
Published: February 2025

The development of artificial intelligence (AI) has had a significant impact on cybersecurity, both as a defense tool and as a threat. One of the biggest emerging risks is deepfake attacks and AI-based cyberattacks, which are increasingly difficult to detect and mitigate. Deepfake technology, which uses Generative Adversarial Networks (GANs), enables video and audio manipulation with a high level of realism, which can be used for disinformation, fraud, and threats to digital security systems. This research aims to analyze cybersecurity threats caused by deepfakes and AI-based attacks, evaluate the effectiveness of conventional security systems in dealing with them, and propose more adaptive AI-based mitigation strategies. The method used in this study is a literature study with a qualitative approach, collecting data from various academic sources, industry reports, and regulations related to cybersecurity. The analysis was carried out using thematic analysis and data triangulation techniques, which allowed mapping of the latest threat trends and solutions that had been implemented. The results show that signature-based security is increasingly ineffective in the face of evolving AI attacks. The implementation of AI in cyber defense systems, such as machine learning-based detection, Zero Trust Architecture (ZTA), and incident response automation systems, is the main solution in dealing with increasingly complex threats. Therefore, an adaptive security approach that combines technology, regulatory policies, and public education is needed to reduce the risk of deepfake attacks and other AI threats.
The Role of Vegetable Production as a Key Factor in Enhancing Cambodian Agriculture: A Systematic Review
Authors: Tan Mengly  , Serey Mardy
Published: February 2025

This systematic review examines the contribution of growing vegetables to effectively strengthen the Cambodian agriculture sector by enhancing food security and uplifting rural communities while promoting economic growth. This study sheds light on how cultivating vegetables impacts nutrition and income in areas by improving food availability and reducing poverty levels. Furthermore, it delves into aspects influencing vegetable cultivation in Cambodia, such as weather conditions, solid quality, input supply access, access to markets, and governmental regulations. The suggested measures include boosting funding for research efforts, improving infrastructure facilities, encouraging the processing of value-added products, supporting farmer groups, and embracing farming practices in Cambodia to develop a robust and thriving agricultural industry that ensures food security, fosters rural advancement, and drives economic progress.
Privacy in the Age of the Internet of Things:
Authors: Delicado Ana , Rosales Marta , Truninger Mónica , Rowland Jussara , Viseu Ana
Published: February 2025

Scientific and media discourse on the Internet of Things (IoT) emphasizes privacy concerns as a possible hurdle to widespread adoption. Drawing on a study conducted with users of home IoT devices and stakeholders, this article examines their perceptions, attitudes, and practices through the framework of privacy concerns, privacy rationales, and privacy work. The results show that users are ambivalent regarding data collection and transfer by IoT devices, oscillating between the advantages of personalization and fears of data commercialization, often accompanied by feelings of powerlessness and privacy resignation. Privacy rationales frequently translate into privacy work that includes rejection, digital housekeeping, and finding appropriate locations in the home. As IoT adoption expands beyond higher educated and higher skilled users, more effort should be made in regulating products and protecting citizens from the increased datafication of everyday life.
Clear Cell Sarcoma with diagnostic utility of PRAME: A Case Report
Authors:   University of Debrecen, Medical Center, Department of Pathology, Chang Chien Yi Che , Mokánszki Attila , Kollár Sándor , Méhes Gábor , Emri Gabriella
Published: February 2025

Clear cell sarcoma (CCS), also known as malignant melanoma of soft parts, is a rare and aggressive soft tissue
sarcoma. We present pioneer case of a 76-year-old female
patient with CCS with novel finding of PRAME negativity,
which can be a potential diagnostic marker to separate
it from malignant melanoma. The clinical presentation,
diag nostic workup, treatment modalities along with a review of relevant literature are also discussed.
The role of polynucleotides in medicine with emphasis on aesthetic medicine
Authors:   Dermart Buda Clinic, Schneider Corinna , Lengyel Zsuzsanna , Baranyai Fanni , Czirbesz Kata , Haller Ákos , Pónyai Katinka
Published: February 2025

The importance of polinucleotide based bioreconstructive
injectable treatments, also used in conventional medicine,
is significantly increasing in aesthetic medicine. In our
article we aimed to provide a clear and concise summary
of the applications of polynucleotides, based on collected
literature data, with a particular focus on their use in
aesthetic medicine.
La comunicación interna: un pilar estratégico para el liderazgo empresarial
Authors: Cuenca Joan , Estanyol i Casals Elisenda
Published: February 2025

Se acaba de presentar la segunda edición del estudio «Prospectiva de la Comunicación Interna en España desde la visión de la dirección general». Esta investigación, impulsada por la Asociación de Directivos y Referentes de Comunicación Interna (DIRCI), ofrece una mirada profunda sobre el papel de la comunicación interna en las organizaciones españolas.
Ugovor or prodaji buduće stvari sa posebnim osvrtom na prodaju nepokretnosti and izgradnji
Authors: Stanišić Slobodan
Published: February 2025

The paper discusses general issues related to the sale of future things with special reference to the sale of real estate under construction, the acquisition of property rights and the competitive relationship between the principle of trust in land registers and the principle of mortgage extensiveness.
European Standards for Insurance Supervision With Reference to Their Implementation in the Republic of Serbia and Bosnia and Herzegovina
Authors: Tošić Iva
Published: February 2025

Corporate scandals that have affected the financial sector have significantly impacted the operations of insurance companies and the trust of insurance service consumers in these companies. At the European Union level, this problem has been recognized, leading to the adoption of the Solvency II Directive. This Directive aims to address challenges and issues faced by insurance companies through appropriate management and supervision of their operations. Supervision includes continuous monitoring to ensure that insurance and reinsurance companies are properly conducting their business and complying with supervisory provisions. In this paper, the author attempts to analyze the supervisory provisions established with the adoption of the Solvency II Directive. In the second part of the paper, the author focuses on analyzing the existing supervisory models in the Republic of Serbia and Bosnia and Herzegovina, considering that both countries aspire to EU membership and will need to align their legislation with European provisions in the future. The author pays particular attention to the supervisory body, noting that in the Republic of Serbia, the insurance market is supervised by the National Bank of Serbia as the central bank, whereas in Bosnia and Herzegovina, a separate Agency for the Supervision of the insurance market has been established.
Activation of strategic thinking of a novice manager as a factor of effective development of an educational organization
Authors: Golovko Anzhela Anatol'evna
Published: February 2025

The article is devoted to the problem of activating the strategic thinking of a novice head of an educational organization. The main subject of the study is strategic thinking as a pedagogical phenomenon that affects the development of an educational institution. The issue of the structure of strategic thinking is considered in detail. It is noted that each manager needs to develop strategic awareness, which is the basis for decision-making of the management of an educational institution. The system-activity approach was chosen as the methodological basis of the research. To study the issue of the transformation of strategic thinking, the author uses general scientific methods of cognition: analysis, synthesis, generalization, induction. This study reveals strategic thinking as a key factor in effective management of an educational organization. For the first time, approaches to the formation of strategic thinking among educational organization managers, including competence-based, situational, process-based, and experience-based approaches, are analyzed. The interrelation of strategic thinking with the criteria of educational organizations management effectiveness, including image, stress management and competitiveness, is revealed. The factors of activation of strategic thinking, such as mentoring, monitoring of the educational environment and resource management, are identified.
Triazole-based click chemistry as strategic for novel therapeutics treatments of cancer: A bibliometric analysis 2007–2024
Authors: Cardona-Galeano Wilson , Yepes Andres F. , Ramírez-Malule Howard
Published: February 2025

Click chemistry is nowadays a versatile strategy for obtaining new bioactive compounds for different diseases, including cancer. Click strategy-based synthetic approaches offer effective routes for the rapid and mild production of bioactive compounds. Triazole ring is known to have significant pharmaceutical value because its derivatives have been shown to have a variety of pharmacological actions, including cancer. There are numerous techniques for triazole ring construction, but click chemistry offers a quick, selective, and dependable approach. The reaction of an azide with a terminal alkyne based on the CuI-catalyzed Huisgen 1,3-dipolar cycloaddition to create 1,2,3-triazoles is the most frequent reaction in click chemistry. The resulting triazole ring is essential in the composition of some clinically approved drugs and other compounds with strong anticancer effects since this fragment may help to improve selectivity, optimize pharmacokinetic features, and overcome resistance. This work shows a bibliometric analysis of published studies on click chemistry and their application in the synthesis of hybrid and conjugate molecules with anticancer activity. Also, we revealed that molecular docking showed the possible mechanism of action of some compounds. Furthermore, bibliometric analysis is shown, providing a holistic overview of the areas in which click chemistry investigations have been focused. Chemistry, materials science, chemical engineering, pharmacology, toxicology and pharmaceutics, and biochemistry, genetics, and molecular biology were the primary fields of study in the field. Finally, the findings show that there has been a notable increase in study on click chemistry, its hybrids, and conjugates, with molecular docking simulations emerging as a new field.
Residence-times distribution function of bistable systemsubjected to noise recycling
Authors: 吴亚珍  , 孙中奎
Published: February 2025

Residence-times distribution function (RTDF), as the distribution function of times between two consecutive switches in bistable systems, is extensively used to characterize the phenomenon of stochastic resonance (SR). However, most of the studies focus on the symmetric bistable systems. As a matter of fact, a majority of asymmetric systems encountered in nature are more universal and practical. Additionally, due to the combination of diverse propagation or transduction mechanisms, noise recycling, constituted by the superposition of a master noise with a secondary component delayed by a time shift , can be generated while a noise is injected into a system and transmitted across the system. Therefore, an asymmetric system subjected to noise recycling is no longer non-Markovian. As a result, it is essential to take the special correlation of noise recycling into account when studying the transition dynamics of particles, which makes it difficult to obtain the analytical formula of RTDF. To solve above problem, a theoretical method to calculate the RTDF of an asymmetric bistable system driven by noise recycling is put forward in this paper. By using the Two-state model with piecewise escape rate, the piecewise escape rate function can be established, based on which the RTDF is derived theoretically with a piecewise formula. It is emphatically demonstrated both theoretically and numerically that the RTDF has exhibited a feedback-induced structure due to the asymmetry of system. Meanwhile, the effects of relative strength and recycling lag on the structure of RTDF are investigated theoretically and numerically, respectively. The results are shown as follows: when the asymmetry satisfies and takes the appropriate values, the RTDF decays exponentially and exhibits a sharp dip at . Nevertheless, on the contrary, under the condition for , the dip at of RTDF almost disappears and the rate of decay of RTDF gets to be accelerated. When the relative strength and recycling lag take the appropriate values separately, the RTDF displays piecewise exponential decay and declines sharply at . It is worth raising that the interval between discontinuities becomes smaller, or even disappears with the relative strength and recycling lag increasing individually. Further, the value of RTDF at presents a maximum with the noise intensity and the relative strength varying, which illustrated that the noise recycling procedure can play a crucial role in inducing the phenomenon of SR in the asymmetric bistable system.?
Mechanisms of Alpha Particle Induced Soft Errors in Nanoscale Static Random Access Memories
Authors: 张战刚  , 叶兵  , 姬庆刚  , 郭金龙  , 习凯  , 雷志锋  , 黄云  , 彭超  , 何玉娟  , 刘杰  , 杜广华
Published: February 2025

In this paper, the Am-241 is used as the alpha particle radioactive source to carry out the soft error mechanism and accelerated test technology research in 65 nm and 90 nm static random access memories (SRAM). Combined with reverse analysis, TRIM and CRèME-MC Monte Carlo simulation, the energy transport process, deposited energy spectrum and cross-section characteristics of alpha particles in the device are revealed. The results show that the soft error sensitivity of the 65 nm device is much higher than that of the 90 nm device, and no flipping polarity is found. According to the real-time measured soft error rate at an altitude of 4300 m in Tibetan Yangbajing area, thermal neutron sensitivity and alpha particle soft error rate, the overall soft error rate of 65 nm SRAM applied at sea level of Beijing city is 429 FIT/Mb, and the contribution of alpha particle is 70.63%. Based on the results of reverse analysis, a three-dimensional simulation model of the device was constructed to study the influence of the incident angle of alpha particles on the single event upset characteristics. It was found that the corresponding deposition energy value at the peak of the number of particles in the sensitive region, decreased by 40% with the incident angle from 0° to 60°. While the single event upset cross section increased by 79% due to the apparent single event upset edge effect in the sensitive region of the 65 nm device.
Pyrotinib after trastuzumab-based adjuvant therapy in patients with HER2-positive breast cancer (PERSIST): A multicenter phase II trial
Authors: Cao Feilin , Ma Zhaosheng , Wu Zenggui , Wu Weizhu , Wang Ouchen , Cui Binbin , Zhu Xiaotao , Hao Jing , Ji Xiaochun , Li Zhanwen , Tao Deyou , Feng Qingjing , Lin Wei , Shi Dongbo , Shu Jingde , Zhou Jichun , Huang Shifen
Published: February 2025

Approximately one-third of patients with HER2-positive breast cancer experienced recurrence within 10 years after receiving 1 year of adjuvant trastuzumab. The ExteNET study showed that 1 year of extended adjuvant neratinib after trastuzumab-based adjuvant therapy could reduce invasive disease-free survival (iDFS) events compared with placebo. This study investigated the efficacy and safety of pyrotinib, an irreversible pan-HER receptor tyrosine kinase inhibitor, after trastuzumab-based adjuvant therapy in patients with high-risk, HER2-positive early or locally advanced breast cancer.This multicenter phase II trial was conducted at 23 centers in China. After enrollment, patients received 1 year of extended adjuvant pyrotinib (400 mg/day), which should be initiated within 6 months after the completion of 1-year adjuvant therapy (trastuzumab alone or plus pertuzumab). The primary endpoint was 2-year iDFS rate.Between January 2019 and February 2022, 141 eligible women were enrolled and treated. As of October 10, 2022, the median follow-up was 24 (interquartile range, 18.0-34.0) months. The 2-year iDFS rate was 94.59% (95% CI: 88.97-97.38) in all patients, 94.90% (95% CI: 86.97-98.06) in patients who completed 1-year treatment, 90.32% (95% CI: 72.93-96.77) in patients who completed only 6-month treatment, 96.74% (95% CI: 87.57-99.18) in the hormone receptor-positive subgroup, 92.77% (95% CI: 83.48-96.93) in the hormone receptor-negative subgroup, 96.88% (95% CI: 79.82-99.55) in the lymph node-negative subgroup, 93.85% (95% CI: 86.81-97.20) in the lymph node-positive subgroup, 97.30% (95% CI: 82.32-99.61) in patients with adjuvant trastuzumab plus pertuzumab, and 93.48% (95% CI: 86.06-97.02) in patients with adjuvant trastuzumab. The most common adverse events were diarrhea (79.4%), fatigue (36.9%), lymphocyte count decreased (36.9%), nausea (33.3%), and hand-foot syndrome (33.3%).Extended adjuvant pyrotinib administrated after trastuzumab-based adjuvant therapy showed promising efficacy in patients with high-risk HER2-positive breast cancer. The follow-up is ongoing to determine the long-term benefit.
Deletion of the moeA gene in Flavobacterium IR1 drives structural color shift from green to blue and alters polysaccharide metabolism
Authors: Escobar Doncel Álvaro , Patinios Constantinos , Campos Alexandre , Walter Costa Maria Beatriz , Turkina Maria V , Murace Maria , Staals Raymond HJ , Vignolini Silvia , Dutilh Bas E , Ingham Colin J
Published: February 2025

Structural colors (SC), generated by light interacting with nanostructured materials, is responsible for the brightest and most vivid coloration in nature. Despite being widespread within the tree of life, there is little knowledge of the genes involved. Partial exceptions are some
Flavobacteriia
in which genes involved in a number of pathways, including gliding motility and polysaccharide metabolism, have been linked to SC. A previous genomic analysis of SC and non-SC bacteria suggested that the pterin pathway is involved in the organization of bacteria to form SC. Thus here, we focus on the
moe
A molybdopterin molybdenum transferase. When this gene was deleted from
Flavobacterium
IR1, the knock-out mutant showed a strong blue shift in SC of the colony, different from the green SC of the wild-type. The
moe
A mutant showed a particularly strong blue shift when grown on kappa-carrageenan and was upregulated for starch degradation. To further analyze the molecular changes, proteomic analysis was performed, showing the upregulation of various polysaccharide utilization loci, which supported the link between
moe
A and polysaccharide metabolism in SC. Overall, we demonstrated that single-gene mutations could change the optical properties of bacterial SC, which is unprecedented when compared to multicellular organisms where structural color is the result of several genes and can not yet be addressed genetically.
The optimal clutch size revisited: separating individual quality from the parental survival costs of reproduction
Authors: Winder Lucy A , Simons Mirre JP , Burke Terry
Published: February 2025

Life-history theory, central to our understanding of diversity in morphology, behaviour and senescence, describes how traits evolve through the optimisation of trade-offs in investment. Despite considerable study, there is only minimal support for trade-offs within species between the two traits most closely linked to fitness – reproductive effort and survival – questioning the theory’s general validity. We used a meta-analysis to separate the effects of individual quality (positive survival/reproduction correlation) from the costs of reproduction (negative survival/reproduction correlation) using studies of reproductive effort and parental survival in birds. Experimental enlargement of brood size caused reduced parental survival. However, the effect size of brood size manipulation was small and opposite to the effect of phenotypic quality, as we found that individuals that naturally produced larger clutches also survived better. The opposite effects on parental survival in experimental and observational studies of reproductive effort provides the first meta-analytic evidence for theory suggesting that quality differences mask trade-offs. Fitness projections using the overall effect size revealed that reproduction presented negligible costs, except when reproductive effort was forced beyond the maximum level observed within species, to that seen between species. We conclude that there is little support for the most fundamental life-history trade-off, between reproductive effort and survival, operating within a population. We suggest that within species, the fitness landscape of the reproduction–survival trade-off is flat until it reaches the boundaries of the between-species fast–slow life-history continuum. Our results provide a quantitative explanation as to why the costs of reproduction are not apparent and why variation in reproductive effort persists within species.