bluuebunny/crossref_metadata_2025 huggingface dataset:
Hydration Structures and Dynamics of In3+ Ion based on Classical Molecular Dynamics Simulation
Authors: Permana Novan A. A. , Suwardi Suwardi
Published: March 2022

The hydration structures and dynamics of In3+ ion have been studied using classical Molecular Dinamics (MD) simulation. The best basis sets were optimized to construct the 2-bodies, 3-bodies correction equations, and analysis of the trajectory file of the simulation results in the form of the parameter of a solvation structure such as RDF, CND, ADF, and dynamic properties, namely the migration of water ligands between the hydration shells. The results showed that the hydration structure of the In3+ ion is In(H2O)93+ and In(H2O)63+, respectively. The geometric arrangement of In3+ hydration obtained through the simulation of classical Molecular Dynamics 2-bd MM 2-bd corrected 3-bd effect is octahedral, which agrees with experimental data and shows the importance of 3-bd correction. The exchange of H2O ligands between the first and second shell or vice versa was not observed during the classical Molecular Dynamics simulation process (2-body + 3-body potential). The hydration structure of In3+ in the first shell was relatively stable.
The Application of Carbon-Chitosan Composite Imprinted Cu in the Wastewater Treatment
Authors: Fillaeli Annisa , Kristianingrum Susila , Sulistyani S. , Fatmala Bella , Fauzi Ilham
Published: March 2022

This research aimed at determining the effect of chitosan in synthesizing imprinted Cu carbon-chitosan composite properties, the effect of imprinting Cu in carbon-chitosan composites to the adsorption efficiency and adsorption capacity of Cu in electroplating waste via batch methods, and the regeneration pattern of the composite. Composites were characterized using FTIR and SEM-EDX. In FTIR spectra, the addition of Cu caused the reduction of -OH and -NH functional groups intensity as the active site of Cu chemical bonding in 3448.72 cm-1. SEM-EDX analysis showed that the carbon-ionic imprinted chitosan composites after desorption contains the element of C = 60.17%, O = 38.8%, Cu = 0.83% and Na = 0.85%. The optimizations of Cu adsorption were studied from the concentration pattern of its variable, measured with Atomic Absorption Spectroscopy (AAS). The results showed that an optimum concentration for adsorption of Cu was 75 mg / L and an optimum contact time for adsorption of Cu was 24 hours with adsorption efficiency of 98.54% and adsorption capacity of 2.62 mg/g respectively. The adsorption yield of electroplating waste showed the adsorption efficiency of 31.62% and adsorption capacity of 367,79 mg/g respectively. Regeneration test was investigated from adsorption-recovery-reactivation (A-Rcov-RAct) steps. This regeneration test was carried out in three cycles. Recovery test was carried out using EDTA 0.05 M and 0.1 M HCl solutions. The efficiency of reactivation was identified from adsorption ability after activated with 0.1 M NaOH from two routes of recoveries. The results showed that recover agents do not influence the adsorption percentage, while to the recovery percentage progress, HCl 0.1M EDTA 0.05M. All routes of reactivation showed the similar results in average 99%
Synthesis of Silver Nanoparticles Balaccida Leaf Extract and Its Anti-Bacterial Activity of E. Coli
Authors: Isnaini Intania
Published: March 2022

The Covid-19 pandemic has become a major problem for public health around the world. One of the ways to prevent Coronavirus is by maintaining hand hygiene using hand sanitizer. The main ingredient of most antiseptics circulating in Indonesia is alcohol which can cause skin irritation. Alcohol substitutes as antiseptics in hand sanitizers are widely available in nature, one of which is the balakacida plant (Chromolaena odorata). The availability of balakacida plants in Indonesia is very abundant as wild plants are often referred to as nuisance plants (weeds). The phytochemical content of balakacida leaves includes saponins, flavonoids, tannins, and alkaloids that have the potential as antibacterial. Balakacida leaf extract has the potential to be used as a source of active ingredients in antiseptic preparations as an alternative to maintain hand hygiene from various parasitic microorganisms. AgNPs are one of the antibacterial and antifungal agents that are effective in inhibiting and killing microorganisms. The optimal variation of CO-SNPs was found at 3 ml of CO-SNPs with an absorption peak of 409 nm and a particle size of 230.1 nm. CO-SNPs produced the best inhibitory value of 12.26 mm on E.coli bacteria.
The effect of project-based learning model on PGSD students’ critical thinking skill
Authors: Nawangsari Nada Savitri , Pujiastuti Pratiwi , Gularso Dhiniaty
Published: March 2022

This study aims to determine the effect of the project-based learning learning model on the thinking skills of PGSD students in the Social Sciences 1 course. The method used in this research is an experiment. The subjects in this study were PGSD students. There are two classes in this research design, namely the experimental class and the control class. The experimental class consisted of 37 students and the control class also consisted of 37 students. Data collection techniques used observation and document analysis. The data analysis technique used in this research is descriptive analysis calculated by comparing the average value of each variable with the standard curve criteria. The analysis prerequisite test uses the normality test. The hypothesis test used is the t-test. The results showed that the project-based learning model has a significant effect in improving students' critical thinking skills.
Multiplication and division of fractions based on numerical literacy electronic module for fifth grade elementary school students
Authors: Triwahyuningtyas Dyah , Sesanti Nyamik Rahayu , Firdayanti Emi , Aziza Ni'matul
Published: March 2022

This research is motivated by the need to provide teaching materials in the form of electronic-based modules (e-modules) integrated with numeracy literacy learning. Where math books are less able to provide delivery related to numeracy literacy. Given the lack of a learning process during the covid 19 period to improve students' abilities in the field of numeracy. The research objective is to develop an e-module for multiplication and division of numeracy literacy fractions for grade 5 elementary school students for practical problem solving. The development research method with the ADDIE model is Analysis, Design, Developments, Implementation, and Evaluation. Analysis of the data used in the form of quantitative and qualitative data analysis techniques through expert validators of teaching materials, media and language as well as teacher and student response questionnaires. The results showed that the e-module of multiplication and division of fractions based on numeracy literacy was declared feasible or valid with an average score of 89.37%. The use of e-modules got a positive response from teachers and students based on a response questionnaire with an average score of 92%. This has an effect on increasing students' understanding in the material of multiplication and division of fractions with an average value of 88. So that the e-module of multiplication and division of fractions based on numeracy literacy can help students in learning mathematics in elementary schools.
Pengaruh Konsentrasi HCl terhadap Mikrostruktur dan Sifat Kemagnetan Nanopartikel Fe3O4 yang Disintesis dari Pasir Besi Pantai Glagah Kulonprogo
Authors: Elda Swastika Pinaka , Hardheyanti Farida , Prasetyowati Rita , Ariswan Ariswan , Warsono Warsono
Published: March 2022

Nanopartikel Fe3O4 yang berasal dari pasir besi pantai Glagah Kulon Progo telah berhasil disintesis menggunakan metode kopresipitasi dengan berbagai variasi konsentrasi HCl (10%, 15%, 25% dan 37%). Pengaruh konsentrasi HCl terhadap mikrostruktur dan sifat kemagnetan dari Fe3O4 dilihat dengan menggunakan XRD, SEM EDX serta VSM. Hasil XRD menunjukkan bahwa Fe3O4 yang dihasilkan memiliki struktur kristal kubik invers spinel. Semakin besar konsentrasi HCl, semakin baik derajat kristalinitasnya. Hasil SEM EDX untuk sampel Fe3O4 dengan konsentrasi HCl 37% menunjukkan ukuran butir (grain) yang hampir sama serta tingkat kemurnian sampel Fe3O4 yang dihasilkan sebesar 100% (Fe 72,42% dan O 27,58%). Hasil VSM menunjukkan Fe3O4 hasil sintesis memiliki sifat superparamagnetik serta bersifat soft magnetic. Nanopartikel Fe3O4 dengan konsentrasi HCl 25% memiliki Hc, Mr dan Mmax masing-masing sebesar 0,0215 T, 11,60 emu/gr dan 36,51 emu/gr. Sedangkan Nanopartikel Fe3O4 dengan konsentrasi HCl 37% memiliki Hc dan Mr yang lebih kecil yaitu masing-masing sebesar 0,0017 T dan 10,83 emu/gr serta Mmax yang lebih besar yaitu 36,82 emu/gr.
Eksplorasi, Seleksi dan Identifikasi Kandidat Bakteri Selulolitik Asal Ekosistem Mangrove Sungailiat, Pulau Bangka
Authors: Janatul Khulud Liza , Febrianti Dwi , Prasetiyono Eva , Robin Robin , Kurniawan Ardiansyah
Published: March 2022

Mangrove memiliki potensi sebagai sumber bakteri pendegradasi selulosa. Pulau Bangka, yang kaya mineral timah, belum dikaji potensi bakteri selulolitiknya. Tujuan penelitian ini untuk mendapatkan kandidat bakteri selulolitik melalui seleksi isolat dari serasah daun lapuk, kayu lapuk, dan lumpur mangrove, serta mengevaluasi patogenisitas kandidat bakteri selulolitik melalui uji patogenisitas secara in vivo. Penelitian terlaksana pada bulan Januari sampai dengan April 2018. Materi uji yang digunakan pada penelitian ini adalah kandidat bakteri selulolitik yang diisolasi dari lumpur, serasah daun dan kayu lapuk dari tumbuhan mangrove dan ikan nila (Oreochromis niloticus). Metode penelitian yang digunakan yaitu metode deskriptif dan eksperimental. Metode deskriptif digunakan pada pengujian bakteri secara in vitro, pegamatan gejala klinis ikan dan kondisi organ dalam ikan setelah diberi perlakuan. Metode eksperimental digunakan pada uji patogenisitas untuk pengamatan parameter kelangsungan hidup. Perlakuan yang diberikan pada ikan uji meliputi injeksi dengan kandidat bakteri selulolitik, injeksi dengan NaCl dan tanpa injeksi. Hasil penelitian menunjukkan bahwa isolasi dan seleksi kandidat bakteri selulolitik didapatkan sebanyak empat belas  isolat. Isolat kandidat bakteri selulolitik yang memiliki aktivitas selulolitik terbaik yaitu isolat bakteri yang berasal dari serasah daun mangrove dengan kode isolat SLS5. Berdasarkan uji biokimia, isolat bakteri SLS5 tersebut teridentifikasi sebagai Bacillus sp. Pengujian patogenisitas bakteri SLS5 membuktikan bahwa bakteri ini bersifat non-patogen (tidak menyebabkan sakit dan kematian) pada ikan Nila.
Pembelajaran pendidikan jasmani yang efektif dan berkualitas
Authors: Iswanto Ari , Widayati Esti
Published: March 2022

Belajar adalah mengajar siswa menggunakan prinsip-prinsip pendidikan dan teori-teori belajar merupakan penentu utama keberhasilan pendidikan. Pendidikan jasmani merupakan instrumen yang efektif untuk mendidik peserta didik, pendidikan jasmani merupakan komponen kunci untuk mencapai pendidikan yang berkualitas dan menjadi bagian integral dari pembelajaran sepanjang hidup. Pendidikan jasmani merupakan sarana untuk mendorong perkembangan keterampilan motorik, kemampuan jasmani, pengetahuan dan penalaran, penghayatan nilai (sikap, mental-emosional-religius dan sosial), serta pembiasaan untuk menjalani gaya hidup sehat untuk merangsang pertumbuhan dan perkembangan yang seimbang. Tidak ada yang lengkap tanpa kehadiran pendidikan pendidikan jasmani, dan tidak ada pendidikan jasmani yang berkualitas dengan konsep pembelajaran yang memiliki inovasi sangat tinggi dan penuh improvisasi, seorang guru dalam menjalankan tugasnya sebagai seorang guru. Pembelajaran juga membutuhkan guru penjas dalam melaksanakan tugas-tugasnya agar benar-benar efektif sehingga akan menjadi pendidikan yang baik dan berkualitas, terutama pemanfaatan waktu ketika proses pembelajaran berlangsung. Effective and high-quality physical education learning AbstractLearning is teaching students use educational principles and theories of learning are a major determinant of educational success. Physical education is an effective instrument for educating students, physical education is a kay component to achieve quality education and become an integral part of learning throughout life. Physical education is a medium, to encourage the development of motor skills, physical ability, knowledge and reasoning, appreciation of values (attitudes, mental-emotional-religious and social), and habituation to lead healthy lifestyles to stimulate growth and balanced development. Nothing is complete without the presence of the education of physical education, and there is no qualified physical education without learning concepts that have a very high innovation and is full of improvisation, a teacher in carrying out his duties as a teacher. Learning also requires a physical education teacher in implementing the tasks to be truly effective it will be a good education and good quality, especially the use of time when progress learning process.
Studi meta analisis cedera pada pemain bola basket
Authors: Siswantoyo Siswantoyo , Ndayisenga Japhet , Putro Kukuh Hardopo
Published: March 2022

Tujuan dari literature review ini adalah untuk mengidentifikasi semua cedera muskuloskeletal dan sendi, penyebab umum dan perawatannya untuk mejadi perhatian bagi pelatih bola basket, untuk merawat siswa dan atlet mereka sesuai dengan trauma yang dialami, tetapi juga peringatan untuk pelatih dari berbagai cabang olahraga lain yang banyak menggunakan sendi lutut dan ankle, dan untuk menunjukkan kepada para peneliti sudut pandang yang belum diteliti. Studi meta analisis dengan literature review dari 50 artikel yang diterbitkan di jurnal internasional yang berbeda terkait dengan ilmu olahraga dari Q4 ke atas dengan pengambilan sampel secara acak. Data dianalisis menurut epidemiologi cedera olahraga pada bola basket. Hasil Total, 50 artikel dipilih. Sebanyak 1.8275 cedera yang diamati, sebagian besar terjadi pada tungkai bawah 718 (3,92%) cedera lutut, 12030 (93,18%) cedera pergelangan kaki (ankle) dan 1.094, (5,96%) cedera lainnya. Anak-anak, remaja (atlet), dan lansia lebih sering mengalami cedera kepala dibandingkan dengan usia lainnya. META ANALYSE STUDY OF THE COMMON INJURIES OF BASKETBALL PLAYERS AbstractsThe aims of this literature review was to identify all musculoskeletal and joints injuries, their common causes, and their treatments in order to pay attention to the basketball teachers, to take care for their students and athletes according to the trauma, but also a warning for the coach trainers of the different disciplines that require a lot of knee and ankle joints, and to show to the researchers the angles which are not yet solicit by the research. Meta analyse study with literature review of 50 articles published in different international journal related to sport science from Q4 and above by random sampling. Data were analysed according to the general epidemiology of sports injuries in basketball. Results In total, 50 articles were selected. A total of 18275 injuries were observed, most of them occurred in the lower limbs 718 (3,92%) Knee injuries,12030(93,18%) ankle injuries and 1094, (5,96%) others injuries. Children, adolescents ( athlete), and elders received head injuries more often compared with the other age.
MENELUSURI JEJAK AWAL PENERBANGAN DI INDONESIA (1913-1950-AN)
Authors: Kurniawan Dadan Adi
Published: March 2022

Minimnya narasi tentang kiprah penerbangan di masa lalu menjadikan pemahaman sejarah terkait moda transportasi seakan pincang. Kebanyakan kajian masih berkutat pada sejarah transportasi darat dan laut, terutama masa kolonial. Padahal keunggulannya dalam menempuh berbagai medan jarak jauh, menjadikan transportasi udara sebagai salah satu primadona pilihan masyarakat modern dalam bermobilitas. Tulisan ini menelusuri lebih lanjut jejak kemunculan dan perkembangan awal penerbangan sipil-militer di Indonesia. Sejak kapan penerbangan mulai ada, faktor apa saja yang melatarbelakangi kemunculannya dan bagaimana dinamika awal perkembangannya. Penelitian ini menggunakan metode sejarah kritis dinama penulis memadukan sumber primer maupun sekunder yang relevan. Hasil dari penelitian ini menunjukkan bahwa penerbangan pertama di Indonesia telah ada sejak dekade kedua abad 20 dan mulai berkembang pesat pada periode 1950-an. Pada awalnya, penerbangan difungsikan untuk keperluan militer disusul penerbangan komersial dalam jumlah terbatas. Kemajuan teknologi di Barat dan persaingan global (perang) saat itu menyebabkan dunia penerbangan mencapai akselerasi kemajuan yang lebih cepat.Kata Kunci: transportasi, bandara, penerbangan, militer, komersial
SEJARAH ORANG BALI DI LAMPUNG 1956 – 1997
Authors: Budianto Aan
Published: March 2022

Penelitian ini secara khusus membahas adaptasi ekonomi dan adaptasi budaya orang Bali di Provinsi Lampung dalam rentang waktu 1956-1997. Pulau Bali yang sebelumnya menjadi tempat bertahannya orang Bali dan Agama Hindu dari arus kedatangan agama Islam dan Kristen, pada abad 20an terpaksa ditinggalkan oleh sebagian orang Bali. Mereka yang meninggalkan Bali menganggap sudah tidak ada masa depan di pulau Bali. Provinsi Lampung menjadi salah satu tempat yang menjadi tujuan orang Bali pada tahun 1956. Di Lampung, orang Bali menghadapi tantangan adaptasi, baik dalam bidang ekonomi maupun budaya. Bagaimana mereka bertahan di tempat baru menjadi menarik untuk ditelisik. Guna memperoleh jawaban atas permasalahan utama tersebut, dipakai metode sejarah kritis dengan penggunaan sumber primer maupun sekunder, seperti foto, arsip, wawancara, pengamatan dan telaah referensi yang relevan. Hasil dari penelitian ini yaitu kondisi ekonomi menjadi faktor pendorong utama orang Bali menuju Lampung pada tahun 1956. Proses migrasi melalui program pemerintah dan swakarsa. Tujuan pertama adalah Seputih Raman, Lampung Tengah. Pertanian sawah menjadi pilihan pekerjaan utama di awal proses adaptasi karena sesuai dengan latar belakang mereka dan kondisi alam di Lampung. Perekonomian orang Bali mengalami kemajuan yang pesat ketika program irigasi dibangun hingga ke Seputih Raman pada tahun 1975. Hal berbeda ditunjukkan oleh orang Bali yang berada di Lampung Utara. Mereka tidak mengolah sawah, melainkan memilih pertanian kebun karena menyesuaikan dengan kondisi geografis alamnya. Kemajuan dalam bidang ekonomi orang Bali yang juga dipengaruhi oleh sikap budaya orang Bali kemudian berpengaruh pada aktualisasi kebudayaan. Berbagai tradisi kebudayaan yang tadinya sulit dilakukan kemudian bisa terlaksana ketika ekonomi mereka mengalami kemajuan. Setelah tahun 1980an, berbagai tradisi dan adat budaya Bali pun semakin berkembang di Lampung.Kata Kunci: Orang Bali, Lampung, Adaptasi, Ekonomi, Budaya.
KEMUNCULAN JAGO BETAWI DAN PERKEMBANGAN DI WILAYAH TANAH ABANG TAHUN 1880-1920
Authors: Albar Fachri
Published: March 2022

AbstrakTanah Abang merupakan salah satu onderdistrik yang terletak di pusat kota Batavia. Memasuki tahun 1735 didirikan sebuah pasar oleh seorang saudagar kaya VOC bernama Justinus Vinck. Pembangunan pasar ini mendorong perekonomi di wilayah Tanah Abang. Pada masa kekuasaan Pemerintah Hindia Belanda banyak terjadi penyimpangan yang dilakukan para tuan tanah, jagoan dan centeng. Akibatnya, banyak perlawanan yang dilakukan oleh para jago. Penelitian ini bertujuan untuk mengetahui keadaan Tanah Abang secara umum, peranan jago dan dampak keberadaan jago terhadap kehidupan masyarakat Tanah Abang pada tahun 1880-1920. Hasil penelitian ini menunjukan bahwa kemunculan jago di wilayah Tanah Abang tidak terlepas dari sosok Pitung. Keberadaan mereka membawa pengaruh terhadap berbagi aspek kehidupan masyarakat Tanah Abang. Para jago mengajarkan teknik-teknik silat kepada para pemuda di Tanah Abang, membawa keamanan bagi para pedagang di Tanah Abang dan mengajarkan nilai-nilai Islam kepada masyarakat Tanah Abang.Kata Kunci: Jago, Betawi, Kehidupan Sosial, Tanah Abang.
Knowledge Gap as Barrier to Influenza Vaccination at a University Primary Care Clinic
Authors: Chen, MD, MS Yi-Wen , Bhandari, PhD, MPA, MBA Ruchi , Fisher, MD, FACP, MSc Melanie
Published: March 2022

INTRODUCTION Since the influenza vaccination rate in West Virginia has been low in comparison to the Healthy People 2020 Goal of 70%, we sought to understand the barriers to vaccination. METHODS A questionnaire was administered to adult patients 18 years and older who sought care between October 1, 2017, and February 28,2018, at a university primary care clinic. The participants were divided into two groups: patients who received or intended to receive the influenza vaccine (vaccinated group) and those who declined it (unvaccinated group). The two groups were compared to assess differences in knowledge, attitudes, and perceptions. RESULTS In total, 178 patients participated. The vaccinated group had increased knowledge of the vaccine's effectiveness (p value < 0.001), vaccine indications (p = 0.044), and reduced disease severity after vaccination (p < 0.001) compared to the unvaccinated group. In addition, the most common reasons for declining vaccination were lack of awareness (34%), fear of side effects (31%), and lack of perceived need or motivation (21%). CONCLUSION A significant knowledge disparity existed between patients who received or planned to receive the influenza vaccine and those who declined, suggesting this knowledge gap may explain the low vaccination rates and emphasizing the importance of counseling patients on the benefits and risks of the vaccine.
Speech Language Pathology Perceptions in the Time of COVID-19: Telehealth and Dysphagia Services in West Virginia
Authors: Ray, MS, CCC/SLP Catherine M. , Corbett Miller, EdD, CCC/SLP Cassaundra , Cottrell, PhD Lesley
Published: March 2022

INTRODUCTION Little is known about the nature and frequency of telehealth services in rural settings, partic- ularly those within West Virginia (WV) with historically limited access to speech and lan- guage services. The purpose of this work is to define these services in WV and to discuss how the 2019 coronavirus pandemic (COVID) precautions affected the need to use tele- health from the speech and language pathol- ogist (SLP) perspective. METHODS An online survey was administered to WV SLPs exploring their feeding and swallowing ex- pertise, service coordination, patient service utilization, and approaches, particularly post- COVID. Our approach yielded responses from 124 SLPs from 37 of the 55 WV counties. RESULTS The majority of the sample provided a variety of services across large regions of WV. SLP experiences were varied. Half of survey re- spondents cited a shortage of experienced clinicians as a primary reason for feeding and swallowing service denial. The majority of LPs had incorporated telehealth into their approach since COVID; however, a subsample reported restrictions in access to technology, policies, and training. Many respondents were not sure of security risks and requested training in security and methods for active participation. CONCLUSIONS Our findings reveal the need for increased systematic and educational support for SLPs providing feeding services via telehealth. Pro- vider access, training, and use of telehealth approaches are pivotal for reaching people with disabilities and are crucial for removing the isolation for this population.
May-Thurner Syndrome in a Ten-Year-Old
Authors: Narumanchi, MD Janani , Narumanchi, MD TaraChandra , Yanamala, PhD Naveena
Published: March 2022

May-Thurner syndrome (MTS) is an unusual cause of intermittent lower extremity edema in pediatric patients. We present the case of a 10-year-old child who presented with gradual onset of intermittent headaches, hematuria, and intermittent worsening edema of his lower extremities. After extensive evaluation, the possible cause of the lower extremity edema was determined to be MTS. Since this diagnosis is usually considered in the differential diagnosis of teenagers and adults, our case raises awareness of this possible diagnosis in younger pediatric patients suspected of having deep vein thromboses.
Understanding the Relationship Between Mood Symptoms and Mobile App Engagement Among Patients With Breast Cancer Using Machine Learning: Case Study
Authors: Baglione Anna N , Cai Lihua , Bahrini Aram , Posey Isabella , Boukhechba Mehdi , Chow Philip I
Published: March 2022

Background

Health interventions delivered via smart devices are increasingly being used to address mental health challenges associated with cancer treatment. Engagement with mobile interventions has been associated with treatment success; however, the relationship between mood and engagement among patients with cancer remains poorly understood. A reason for this is the lack of a data-driven process for analyzing mood and app engagement data for patients with cancer.

Objective

This study aimed to provide a step-by-step process for using app engagement metrics to predict continuously assessed mood outcomes in patients with breast cancer.

Methods

We described the steps involved in data preprocessing, feature extraction, and data modeling and prediction. We applied this process as a case study to data collected from patients with breast cancer who engaged with a mobile mental health app intervention (IntelliCare) over 7 weeks. We compared engagement patterns over time (eg, frequency and days of use) between participants with high and low anxiety and between participants with high and low depression. We then used a linear mixed model to identify significant effects and evaluate the performance of the random forest and XGBoost classifiers in predicting weekly mood from baseline affect and engagement features.

Results

We observed differences in engagement patterns between the participants with high and low levels of anxiety and depression. The linear mixed model results varied by the feature set; these results revealed weak effects for several features of engagement, including duration-based metrics and frequency. The accuracy of predicting depressed mood varied according to the feature set and classifier. The feature set containing survey features and overall app engagement features achieved the best performance (accuracy: 84.6%; precision: 82.5%; recall: 64.4%; F1 score: 67.8%) when used with a random forest classifier.

Conclusions

The results from the case study support the feasibility and potential of our analytic process for understanding the relationship between app engagement and mood outcomes in patients with breast cancer. The ability to leverage both self-report and engagement features to analyze and predict mood during an intervention could be used to enhance decision-making for researchers and clinicians and assist in developing more personalized interventions for patients with breast cancer.
Patient-Level Fall Risk Prediction Using the Observational Medical Outcomes Partnership’s Common Data Model: Pilot Feasibility Study
Authors: Jung Hyesil , Yoo Sooyoung , Kim Seok , Heo Eunjeong , Kim Borham , Lee Ho-Young , Hwang Hee
Published: March 2022

Background

Falls in acute care settings threaten patients’ safety. Researchers have been developing fall risk prediction models and exploring risk factors to provide evidence-based fall prevention practices; however, such efforts are hindered by insufficient samples, limited covariates, and a lack of standardized methodologies that aid study replication.

Objective

The objectives of this study were to (1) convert fall-related electronic health record data into the standardized Observational Medical Outcome Partnership's (OMOP) common data model format and (2) develop models that predict fall risk during 2 time periods.

Methods

As a pilot feasibility test, we converted fall-related electronic health record data (nursing notes, fall risk assessment sheet, patient acuity assessment sheet, and clinical observation sheet) into standardized OMOP common data model format using an extraction, transformation, and load process. We developed fall risk prediction models for 2 time periods (within 7 days of admission and during the entire hospital stay) using 2 algorithms (least absolute shrinkage and selection operator logistic regression and random forest).

Results

In total, 6277 nursing statements, 747,049,486 clinical observation sheet records, 1,554,775 fall risk scores, and 5,685,011 patient acuity scores were converted into OMOP common data model format. All our models (area under the receiver operating characteristic curve 0.692-0.726) performed better than the Hendrich II Fall Risk Model. Patient acuity score, fall history, age ≥60 years, movement disorder, and central nervous system agents were the most important predictors in the logistic regression models.

Conclusions

To enhance model performance further, we are currently converting all nursing records into the OMOP common data model data format, which will then be included in the models. Thus, in the near future, the performance of fall risk prediction models could be improved through the application of abundant nursing records and external validation.
Searching for HIV and AIDS Health Information in South Africa, 2004-2019: Analysis of Google and Wikipedia Search Trends (Preprint)
Authors: Okunoye Babatunde , Ning Shaoyang , Jemielniak Dariusz
Published: March 2022

BACKGROUND

AIDS, caused by HIV, is a leading cause of mortality in Africa. HIV/AIDS is among the greatest public health challenges confronting health authorities, with South Africa having the greatest prevalence of the disease in the world. There is little research into how Africans meet their health information needs on HIV/AIDS online, and this research gap impacts programming and educational responses to the HIV/AIDS pandemic.

OBJECTIVE

This paper reports on how, in general, interest in the search terms “HIV” and “AIDS” mirrors the increase in people living with HIV and the decline in AIDS cases in South Africa.

METHODS

Data on search trends for HIV and AIDS for South Africa were found using the search terms “HIV” and “AIDS” (categories: health, web search) on Google Trends. This was compared with data on estimated adults and children living with HIV, and AIDS-related deaths in South Africa, from the Joint United Nations Programme on HIV/AIDS, and also with search interest in the topics “HIV” and “AIDS” on Wikipedia Afrikaans, the most developed local language Wikipedia service in South Africa. Nonparametric statistical tests were conducted to support the trends and associations identified in the data.

RESULTS

Google Trends shows a statistically significant decline (P<.001) in search interest for AIDS relative to HIV in South Africa. This trend mirrors progress on the ground in South Africa and is significantly associated (P<.001) with a decline in AIDS-related deaths and people living longer with HIV. This trend was also replicated on Wikipedia Afrikaans, where there was a greater interest in HIV than AIDS.

CONCLUSIONS

This statistically significant (P<.001) association between interest in the search terms “HIV” and “AIDS” in South Africa (2004-2019) and the number of people living with HIV and AIDS in the country (2004-2019) might be an indicator that multilateral efforts at combating HIV/AIDS—particularly through awareness raising and behavioral interventions in South Africa—are bearing fruit, and this is not only evident on the ground, but is also reflected in the online information seeking on the HIV/AIDS pandemic. We acknowledge the limitation that in studying the association between Google search interests on HIV/AIDS and cases/deaths, causal relationships should not be drawn due to the limitations of the data.
Patient-Level Fall Risk Prediction Using the Observational Medical Outcomes Partnership’s Common Data Model: Pilot Feasibility Study (Preprint)
Authors: Jung Hyesil , Yoo Sooyoung , Kim Seok , Heo Eunjeong , Kim Borham , Lee Ho-Young , Hwang Hee
Published: March 2022

BACKGROUND

Falls in acute care settings threaten patients’ safety. Researchers have been developing fall risk prediction models and exploring risk factors to provide evidence-based fall prevention practices; however, such efforts are hindered by insufficient samples, limited covariates, and a lack of standardized methodologies that aid study replication.

OBJECTIVE

The objectives of this study were to (1) convert fall-related electronic health record data into the standardized Observational Medical Outcome Partnership's (OMOP) common data model format and (2) develop models that predict fall risk during 2 time periods.

METHODS

As a pilot feasibility test, we converted fall-related electronic health record data (nursing notes, fall risk assessment sheet, patient acuity assessment sheet, and clinical observation sheet) into standardized OMOP common data model format using an extraction, transformation, and load process. We developed fall risk prediction models for 2 time periods (within 7 days of admission and during the entire hospital stay) using 2 algorithms (least absolute shrinkage and selection operator logistic regression and random forest).

RESULTS

In total, 6277 nursing statements, 747,049,486 clinical observation sheet records, 1,554,775 fall risk scores, and 5,685,011 patient acuity scores were converted into OMOP common data model format. All our models (area under the receiver operating characteristic curve 0.692-0.726) performed better than the Hendrich II Fall Risk Model. Patient acuity score, fall history, age ≥60 years, movement disorder, and central nervous system agents were the most important predictors in the logistic regression models.

CONCLUSIONS

To enhance model performance further, we are currently converting all nursing records into the OMOP common data model data format, which will then be included in the models. Thus, in the near future, the performance of fall risk prediction models could be improved through the application of abundant nursing records and external validation.
Authors’ Reply to: Using Caution When Interpreting Gender-Based Relative Risk. Comment on “The Effect of Cardiovascular Comorbidities on Women Compared to Men: Longitudinal Retrospective Analysis” (Preprint)
Authors: Dervic Elma , Deischinger Carola , Haug Nina , Leutner Michael , Kautzky-Willer Alexandra , Klimek Peter
Published: March 2022

UNSTRUCTURED

n/a
The Childhood Immunization Reminder Project (ChIRP): A pilot test of text message immunization reminders to improve immunization attendance in Alberta, Canada (Preprint)
Authors: MacDonald Shannon E , Marfo Emmanuel , Sell Hannah , Assi Ali , Frank-Wilson Andrew , Atkinson Katherine , Kellner James D , McNeil Deborah , Klein Kristin , Svenson Lawrence W
Published: March 2022

BACKGROUND

Vaccine coverage for 18-month-old children in Canada is often below recommended levels, which may be partially due to parental forgetfulness. Text message reminders have been shown to potentially improve childhood immunization uptake, but were not widely utilized in Alberta, Canada. Additionally, it has been noted that language barriers may impede immunization service delivery but continue to be unaddressed in many existing reminder/recall systems.

OBJECTIVE

We aimed to assess the effectiveness and acceptability of using text messages, containing a link to online immunization information in different languages, to remind parents of their child’s 18-month immunization appointment.

METHODS

The Childhood Immunization Reminder Project (ChIRP) was a pilot intervention at two public health centres, one each in Lethbridge and Edmonton, Alberta, Canada. Two text message reminders were sent to parents: (1) a booking reminder 3 months before their child turned 18 months old, and (2) an appointment reminder three days before their scheduled appointment. Booking reminders included a link to the study website hosting immunization information in nine languages. To evaluate the intervention effectiveness, we compared absolute attendance no-show rates pre- and post-intervention. Acceptability of the intervention was evaluated through online surveys completed by parents and public health centre staff. Google Analytics was used to determine how often the online immunization information was accessed, from where, and in which languages.

RESULTS

Following the intervention, the Edmonton health centre had a reduction of 6.4% (95% CI: 3.0, 9.8) in appointment no-shows, with no change at the Lethbridge health centre (0.8%; 95% CI: -1.4, +3.0). Acceptability surveys were completed by 222 parents (response rate: 23.9%) and 22 staff. Almost all (>95%) respondents indicated that the reminders were helpful and had useful suggestions for improvements. All surveyed parents (100.0%) found it helpful to read the online immunization information in their language of choice. Google Analytics data showed that the immunization information was most often read in English (57.0%), Punjabi (25.1%), Arabic (6.3%), Spanish (5.8%), Italian (1.9%), Chinese (1.9%), French (1.0%), Tagalog (0.5%), and Vietnamese (0.5%).

CONCLUSIONS

The study findings support the use of text message reminders as a convenient and acceptable method to minimize parental forgetfulness and potentially reduce appointment no-shows. The diverse languages accessed in the online immunization information suggest the need to provide appropriate translated immunization information. Further research is needed to evaluate the impact of text message reminders on childhood immunization coverage in different settings.
Chatbot
Authors: Lyngdoh Fredrick B , R Raghavendra
Published: March 2022

Abstract: Chatbot can be understood as a software that can chat with people using artificial intelligence. This software can also perform tasks such as quickly responding to users, informing them, helping to purchase products and providing the customers better services. A chatbot is a computer software program that can conduct a conversation by an auditory or textual methods. Chatbot has become more popular in business group in the present as it can reduce customers service costs and handles multiple users at a time. But it is yet to accomplish tasks that needs to make chatbots as efficient as possible. In this project, we aim to design a chatbot that provides a genuine and accurate answer for queries using Artificial Intelligence Markup Lanugages (AIML) and with the present of python platform. Keywords: Chatbot, Artificial Intelligence, Computer Software, Services, Users, Artificial Intelligence Markup Languages.
A Brief on Water Pump Level Adjustment & Monitoring System Using Arduino Uno
Authors: Kalwe Chirayu , Sarode Sourabh , Gedam Akshay , Bhaisare Neha , Bagal Shishir
Published: March 2022

Abstract: Arduino is an ASCII text file programmable circuit card that will be programmed to sense and manage objects within the physical world. By responding to sensors and inputs, the Arduino is ready to act with an outsized array of outputs equivalent to LEDs, motors, and displays. The ESP8266 is capable of either hosting a degree application or offloading all LAN networking functions from another application processor. A pump is a tool that moves fluids (liquids or gases) by mechanical action. Pumps operate via several energy sources, alongside manual operation, electricity, engines, or wind power. An integrated development setting (IDE) is also a coding system application that provides comprehensive facilities to pc programmers for software package development. Some IDEs, appreciate NetBeans and Eclipse, contain the obligatory compiler, interpreter, or both.
KONSEP NUSUK DALAM AL-QUR’AN (Kajian tafsir maudhu’i) Analisis Etimologi dan terminologi Manasik
Authors: Suhemi Emi
Published: March 2022

Penelitian ini berjudul Konsep Nusuk dalam Al-Quran. Peneliian ini menggunakan pendekatan tafsir maudhu’i. Adapun langkah-langkah yang ditempuh dalam pendekatan ini yaitu mengumpulkan ayat-ayat yang bertemakan nusuk di dalam Al-Quran, kemudian juga mengumpulkan hadist-hdist yang bertemakan nusuk. Serta juga beberapa kamus yang akan dipakai untuk menemukan pemahaman nusuk secara etimologi. Adappun tujuan dari penelitian ini adalah mengetahui akan konsep nusuk di dalam Al-Quran. Yang akan dibahas pada penelitian ini adalah bagaimana konsep nusuk didalam Al-quran. Adapun hasil dari penelitian ini adalah bahwa nusuk itu tidak hanya dimaknai sebagai ritual ibadah haji, tetapi juga mengandung makna yang luas seperti zuhud dan taqarrub kepada Allah.
Profil Physalis minima L. dari Berbagai Etnis di 9 (Sembilan) Provinsi Indonesia Secara HPLC dan Kemometrik
Authors: Alegantina Sukmayati , Setyorini Herni Asih , Oktoberia Intan Sari , Winarsih Winarsih , Aini Nurul
Published: March 2022

Many Indonesian people use plants for medicine and health care. In 2017, the Center for Research and Development of Medicinal Plants and Traditional Medicines (B2P2TOOT), the National Institute of Health Research and Development (Badan Litbangkes) conducted a Research on Medicinal Plants and Herbs (Ristoja) by collecting 30 types of medicinal plants. Physalis minima L. (ciplukan) is one of the Ristoja plants that has been studied at the Pharmaceutical Laboratory, Center of Health Research and Development of Biomedical and Basic Health Technology, Badan Litbangkes. This study aimed to determine the chromatogram profile of plants to obtain plant quality and clusters between plants from different geographic origins using chemometric applications. There were 66 ciplukan samples collected from 15 ethnic groups in 9 provinces in Indonesia. Analysis was performed using High Performance Liquid Chromatography (HPLC) with a Photo Diode Array (PDA) detector at a wavelength (λ) of 254 nm and 366 nm. From the optimization results, the HPLC eluent used was a mixture of acetonitrile and methanol with a gradient system. The results from HPLC were chemometrically processed with data interpretation using Principal Component Analysis (PCA). PCA results of HPLC chromatograms at λ 254 nm and 366 nm, showed 2 clusters, which indicated that Physalis minima L. Ristoja results had 2 phytochemical profiles. The peak detected at λ 366 nm was more complex than at λ 254 nm.

Abstrak

Masyarakat Indonesia banyak memanfaatkan tanaman untuk pengobatan maupun perawatan kesehatan. Pada tahun 2017, Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional (B2P2TOOT), Badan Penelitian dan Pengembangan Kesehatan (Badan Litbangkes) telah melakukan Riset Tanaman Obat dan Jamu (Ristoja) dengan mengumpulkan 30 jenis tanaman obat. Physalis minima L. (ciplukan) merupakan salah satu tanaman hasil Ristoja yang telah diteliti di Laboratorium Farmasi, Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan, Badan Litbangkes. Penelitian bertujuan mengetahui profil kromatogram tanaman untuk mendapatkan kualitas mutu tanaman dan klaster antara tanaman dari asal geografis yang berbeda menggunakan aplikasi kemometrik. Sampel ciplukan yang terkumpul berjumlah 66 buah dari 15 etnis pada 9 provinsi di Indonesia. Analisis dilakukan menggunakan High Performance Liquid Chromatography (HPLC) dengan detektor Photo Diode Array (PDA) pada panjang gelombang (λ) 254 nm dan 366 nm. Dari hasil optimasi, eluen HPLC yang digunakan adalah campuran asetonitril dan metanol dengan sistem gradien. Hasil dari HPLC diolah secara kemometrik dengan interpretasi data menggunakan Principal Component Analysis (PCA). Hasil PCA dengan HPLC pada λ 254 nm and 366 nm, masing-masing memiliki 2 klaster yang menunjukkan bahwa Physalis minima L. hasil Ristoja memiliki 2 profil fitokimia. Puncak yang terdeteksi pada λ 366 nm lebih kompleks dibanding λ 254 nm.
Konstruksi Plasmid Pengekspresi Antigen Gag dan Protein Penghantar VP22 untuk Pengembangan Vaksin HIV-1
Authors: Remelia Melinda , Bela Budiman , Widyaningtyas Silvia Tri , Ibrahim Fera
Published: March 2022

The endogenous HIV-1 vaccine based on Gag protein is expected to stimulate the immune response of CD8+ T cells (cytotoxic). The Gag protein that has been produced by the E.coli prokaryote system is an exogenous antigen. The fusion of VP22 protein is expected to deliver Gag antigen into the cytoplasm of cell, observed by eGFP markers. Sequences of VP22 (114 pb), GagHIV-1 (1506 pb), and eGFP (733 pb) were inserted into the pQE80L, respectively. The recombinant protein was expressed in the E.coli system and purified by the Ni-NTA method. Antigen delivery fused with VP22 and eGFP was observed with fluorescence and confocal microscopy. The recombinant plasmid constructs of protein expression eGFP, VP22-eGFP, GagHIV-1-eGFP, VP22-GagHIV-1-eGFP were verified by DNA sequencing according to the reference. The recombinant plasmid constructs of Gag HIV-1-eGFP and VP22-GagHIV-1-eGFP still need to be optimized so they can be expressed in the E.coli system.  The recombinant protein VP22-eGFP (27.02 kDa) was succesfully obtained and fluorescent green (entered) into the cytoplasm and nucleus of vero cells. In addition to the HIV-1 vaccine, this recombinant plasmids pQE80L-eGFP and pQE80L-VP22-eGFP also have the potential to be used as tools in the development of endogenous vaccines for another viruses/microbes.
Abstrak
Vaksin endogen HIV-1 berbasis protein Gag diharapkan dapat menstimulus respons imun sel T CD8+ (sitotoksik). Protein Gag yang telah diproduksi dengan sistem prokariota E.coli merupakan antigen yang bersifat eksogen. Fusi protein VP22 diharapkan mampumenghantarkan antigen Gag masuk ke sitoplasma sel, diamati dengan marker eGFP.  Sekuens VP22 (114 pb), GagHIV1 (1506 pb), dan eGFP (733 pb) telah diinsersikan pada vektor pQE80L. Protein rekombinan diekspresikan pada sistem E.coli dan dipurifikasi dengan metode Ni-NTA. Penghantaran antigen yang difusikan dengan VP22 dan marker eGFP diamati dengan mikroskop fluoresens dan konfokal. Konstruksi plasmid rekombinan pengekspresi protein eGFP, VP22-eGFP, GagHIV1-eGFP, dan VP22-GagHIV1-eGFP telah diverifikasi dengan sekuensing DNA sesuai dengan sekuen referensi. Plasmid rekombinan pengekspresi GagHIV1-eGFP dan VP22-GagHIV1-eGFP masih perlu dioptimasi agar dapat diekspresikan di sistem E.coli. Protein rekombinan VP22-eGFP (27,02 kDa) telah berhasil diperoleh serta berpendar fluoresens hijau  (masuk) ke sitoplasma dan nukleus sel vero. Selain vaksin HIV-1, plasmid rekombinan pQE80L-eGFP dan pQE80L-VP22-eGFP juga berpotensi dapat digunakan sebagai ‘tools’ dalam pengembangan vaksin endogen dari virus atau mikroba lainnya.