bluuebunny/crossref_metadata_2025 huggingface dataset:
Оптический экспресс-мониторинг белка интерналина Б патогенной бактерии Listeria monocytogenes с использованием ГКР-активных кремниевых нанонитей, декорированных серебром
Authors: Гончар К.А. , Алексеева Е.А. , Гюппенен О.Д. , Божьев И.В. , Калинин Е.В. , Ермолаева С.А. , Осминкина Л.А.
Published: October 2022

Комбинационное рассеяние с поверхностным усилением . гигантское комбинационное рассеяние (ГКР) представляет собой мощный метод вибрационной оптической спектроскопии, который позволяет осуществлять высокочувствительное обнаружение молекул при очень малой концентрации вещества за счет усиления электромагнитных полей, создаваемых возбуждением локализованных поверхностных плазмонов на поверхности наноструктур благородных металлов. В работе разработана методика изготовления композитных наноструктур кремниевых нанонитей, декорированных серебром (AgКНН). Исследована ГКР-активность AgКНН для детектирования белков на примере человеческого сывороточного альбумина. Впервые показана возможность экспресс-диагностики белка InlB патогенных бактерий Listeria monocytogenes методом ГКР с использованием полученных наноструктур. В спектрах InlB, адсорбированного на AgКНН с различными концентрациями, наблюдаются четкие пики, соответствующие комбинационному рассеянию на молекулах белковой природы. Из полученных экспериментальных данных рассчитан предел обнаружения InlB, который составляет 4.8· 10-9 M. Представленные результаты свидетельствует о высоком потенциале применений полученных композитных наноструктур для диагностики различных белков методом ГКР. Ключевые слова: гигантское комбинационное рассеяние, кремниевые нанонити, композитные наноструктуры, альбумин, листерии, интерналин В.
Влияние лигандов на фотопроводимость нанопластин HgTe
Authors: Парфенов П.С. , Гриневич Я.В. , Соколова А.В. , Бабаев А.А. , Скурлов И.Д. , Черевков С.А. , Колесников И.Е. , Литвин А.П.
Published: October 2022

Near-IR semiconductor colloidal nanoplatelets (NPs) are a new and promising class of materials for the development of photodetectors because they can effectively absorb visible and infrared optical radiation. In this work, we study the photoconductivity of HgTe colloidal nanoplatelets with ligands of 1,2-ethanedithiol and tetrabutylammonium iodide. It has been shown that the choice of ligands is a key factor in achieving high operational characteristics. It has been shown that the photoconductivity sensitivity reaches 0.995 and the specific detectivity reaches 1.2×109 Jones when 1,2-ethadithiol is used as ligands.
Расчет напряженности электрического поля в интерференционных покрытиях
Authors: Котликов Е.Н. , Тропин А.Н.
Published: October 2022

A technique for calculating the electric field in interference coatings is described. The technique is used to find areas in the coating structure with electric field minima. Thin absorbing metal films are introduced into these areas during design. The results of calculating the transmission spectra of narrow-band interference filters with absorbing metal films are presented. It is shown that such metal-dielectric thin-film structures block radiation in the long-wavelength region of the spectrum.
Phân bố và quan hệ không gian của các loài cây gỗ trong rừng lá rộng thường xanh ở Vườn Quốc gia Kon Ka Kinh, tỉnh Gia Lai
Authors: Nguyễn Văn Quý , Phạm Thanh Hà , Nguyễn Thanh Tuấn , Nguyễn Văn Hợp
Published: October 2022

Nghiên cứu này được thực hiện để làm sáng tỏ cơ chế cùng chung sống của các loài cây gỗ rừng lá rộng thường xanh tại Vườn Quốc gia Kon Ka Kinh, tỉnh Gia Lai. Tất cả các cây có đường kính ngang ngực (DBH) ≥ 2,5 cm trong 3 ô tiêu chuẩn 1 ha đã được lập bản đồ, xác định DBH và tên loài. Kết quả cho thấy mô hình không gian của 12/20 loài được phân tích là phân bố cụm ở quy mô nhỏ < 15 m, phân bố ngẫu nhiên và đều có xu hướng tăng lên ở quy mô lớn > 15 m. Quan hệ độc lập chiếm tỉ lệ cao (75-90%), quan hệ cạnh tranh và tương hỗ chiếm tỉ lệ thấp (10-25%), sự liên kết không gian của các loài chủ yếu là độc lập hoặc tách biệt ở quy mô lớn. Phát tán giới hạn, tính không đồng nhất của môi trường và tỷ lệ tử vong phụ thuộc vào mật độ là ba cơ chế điều chỉnh mô hình phân bố, quan hệ và các kiểu liên kết không gian của các loài cây gỗ tại khu vực nghiên cứu.
Mở rộng lợi thế cạnh tranh thông qua văn hoá tổ chức, hợp tác chuỗi cung ứng và chia sẻ kiến thức tại các công ty dược phẩm trên địa bàn thành phố Hồ Chí Minh
Authors: Nguyễn Văn Ít
Published: October 2022

Nghiên cứu này được thực hiện trên cơ sở kế thừa lý thuyết nền tảng nguồn lực (RBT) nhằm xem xét mở rộng lợi thế cạnh tranh thông qua văn hoá tổ chức, hợp tác chuỗi cung ứng và chia sẻ kiến thức. Văn hoá tổ chức được xem xét trên phương diện chủ nghĩa tập thể, định hướng dài hạn, cân đối quyền lực; hợp tác chuỗi cung ứng được tiếp cận trên khía cạnh đảm bảo không gián đoạn; chia sẻ kiến thức mới thông qua cộng tác. Dựa vào khảo sát 269 lãnh đạo, quản lý và nhân viên đang làm việc tại các công ty dược phẩm trên địa bàn thành phố Hồ Chí Minh, phương pháp phân tích mô hình cấu trúc (SEM) được sử dụng để phân tích dữ liệu và kiểm định các giả thuyết nghiên cứu. Kết quả đã chỉ ra vai trò tiền đề của văn hoá tổ chức trong việc nuôi dưỡng, thúc đẩy hợp tác chuỗi cung ứng và chia sẻ kiến thức. Đồng thời, văn hoá tổ chức, hợp tác chuỗi cung ứng và chia sẻ kiến thức là những yếu tố tác động đến mở rộng lợi thế cạnh tranh của doanh nghiệp dược phẩm.
Schizophrenia, Maslows Hierarchy and Losers
Authors: - Anon
Published: October 2022

None
The Influences and Improvement Strategies of the Use of Accurate English Phonetics on English Listening for Chinese University Freshmen
Authors: Li Hexiao
Published: October 2022

Due to less attention to the English phonetics improvements was paid by high school English teaching, many Chinese university freshmen lack of the most basic phonetics knowledge, for example, their verbal continuous reading is not coherent and their incomplete blasting phonetics is not clear, some freshmen even do not know how to spell words correctly according to their phonetics. This situation has made many negative effects on China’s university English EFL teaching, especially for their improvement of listening comprehension ,but if both teachers and freshmen are aware of this problems, the university English classroom teaching can be effectively improved.
E3 ubiquitin ligase components in GtoPdb v.2022.3
Authors: Faccenda Elena , Layfield Robert
Published: October 2022

Ubiquitination (a.k.a. ubiquitylation) is a protein post-translational modification that typically requires the sequential action of three enzymes: E1 (ubiquitin-activating enzymes), E2 (ubiquitin-conjugating enzymes), and E3 (ubiquitin ligases) [28]. Ubiquitination of proteins can target them for proteasomal degradation, or modulate cellular processes including cell cycle progression, transcriptional regulation, DNA repair and signal transduction. E3 ubiquitin ligases, of which there are >600 in humans, are a family of highly heterogeneous proteins and protein complexes that recruit ubiquitin-loaded E2 enzymes to mediate transfer of the ubiquitin molecule from the E2 to protein substrates. Target substrate specificity is determined by a substrate recognition subunit within the E3 complex. E3 ligases are being exploited as pharmacological targets to facilitate targeted protein degradation (TPD), as an alternative to small molecule inhibitors [3], through the development of proteolysis targeting chimeras (PROTACs) and molecular glues.
Francisco de Goya: una mirada desde México
Authors: Ortiz de Montellamo García Jorge Eduardo , García solís Carlos Adolfo ,   Secretaria de Cultura del Estado de Michoacán, Acosta Clemente María Teresa ,   Universidad de Morelia
Published: October 2022

Esta memoria compila una selección de las ponencias presentadas durante el coloquio Francisco de Goya: vida y obra, que se realizó durante 2014 en la ciudad de Morelia. Los doce ensayos que la componen reinterpretan, desde México, la obra y el contexto histórico que le tocó vivir al maestro zaragozano. En particular, los artículos revisan las expresiones alegóricas y críticas de las contradicciones sociales que aparecen en sus pinturas y grabados, haciendo énfasis en las series de Los Caprichos, Los Disparates y las “Pinturas negras”. Este libro, coordinado por Rie Arimura, Erandi Lisset Ávalos Aburto e Ireri Ortiz Silva, nos presenta el espíritu de la época, el rostro del tiempo y el sarcasmo en la obra de Goya y Lucientes, sus valores expresivos, sus monstruos y sus claroscuros, notas sobre sus exposiciones en México y la influencia del maestro español sobre algunos destacados artistas mexicanos y de otras partes del mundo. Una obra que crea un espacio de reflexión y abre nuevas líneas de investigación en torno a las creaciones del genial artista.
Celebración y sonoridad en Hispanoamérica (siglos XVI y XIX)
Authors: Hernández Pech Salvador Adán ,   Archivo del Cabildo Catedral Metropolitana de México, Departamento de Catalogación de la Biblioteca Nacional
Published: October 2022

Hablar de los caminos es hablar de la historia de la humanidad y del proceso de apropiación del paisaje y los territorios. Así como la red hidrográfica se percibe como las “venas” de la tierra, los caminos pueden reconocerse como las “venas” de la sociedad, por donde fluyen los individuos, grupos y pueblos transportando mercancías, herramientas, sueños, esperanzas y desengaños. El presente libro es el resultado del esfuerzo coordinado de los autores a partir de un coloquio celebrado en noviembre de 2014, en la entonces muy joven Escuela Nacional de Estudios Superiores Unidad Morelia, con el objetivo de visibilizar la trascendencia y relevancia del enfoque geohistórico para comprender los procesos de apropiación y modelado del paisaje, tomando como pretexto los caminos para resaltar su importancia en el análisis geohistórico de los paisajes y su patrimonio. Como lo muestra la obra, los caminos son un objeto fundamental de estudio desde la perspectiva geohistórica, ya que invitan a ser analizados desde los aspectos espaciales y temporales de su conformación, utilización, transformación y cómo pueden ser pretexto o fundamento para promover nuevas acciones de apropiación y uso de los elementos del paisaje, lo que podemos constatar en los diferentes capítulos que la integran.
Systematic Review on Respiratory Toxicology Caused by Synthetic Air Fresheners
Authors: Balasubramani Geetha , J Paul Pradeep
Published: October 2022

Abstract: The main objective of this comprehensive review research on the various kinds of respiratory illness caused by the synthetic air fresheners. Air fresheners are widely used in indoor built environmental settings such as businesses, schools, residences, transit, hotels, hospitals, care facilities, and a variety of private and governmental structures. In order to create a comfortable indoor atmosphere, air fresheners are made to add aroma to the air or to cover up odours. Air fresheners, however, can produce and emit a variety of potentially toxic air pollutants that can deteriorate air quality, regardless of their intended use. Volatile organic compounds (VOCs) found in air fresheners include ones that may be harmful air pollutants, carcinogens, or substances linked to adverse health consequences including asthma, COPD and so on. Air fresheners have been identified as a major source of volatile organic compounds in buildings from the perspective of indoor air quality. Air fresheners have been linked to negative health impacts include neonatal illness, asthma symptoms, mucosal symptoms, migraine headaches, and breathing problems. In this research review we mainly focused on synthetic air freshener, emits various kinds of VOC’s that caused different types of respiratory illness. This review also investigates a paradoxical effect that the synthetic air fresheners meant to enhance indoor environments may also present unanticipated & unidentified risk. Finally, we discussed about the International and National market size of the air freshener.
The Islamic Reformist Musa Bigiev as Portrayed by Hilmi Ziya Ülken
Authors: Nasyrov I. R.
Published: October 2022

The present article is devoted to the study of the outstanding Russian Muslim theologian and modernist Musa Bigiev’s legacy that was carried out by the Turkish scholar Hilmi Ziya Ülken. It focuses on Hilmi Ziya Ülken’s interpretation of ideas of Musa Bigiev in the historical and socio-c ultural context in the Islamic East and Turkey in the XIX–beginning of the XX centuries.
Issuing Fatwas on Marriage and Family Relations According to the Turkish Directorate of Religious Aff airs
Authors: Ganiev I. A.
Published: October 2022

This paper presents an analysis of the process of fatwa issuing according to the High Council of Religious Aff airs of Turkey (marriage and family relations). Particularly, fatwas are considered on the need to register marriage with state bodies, divorce while alcoholic intoxication, three simultaneous divorces, etc. The article provides a detailed analysis of the methodology used in issuing these fatwas, which is based on modern approaches to ij tihad, exactly: al-ijtihad al-madhhabi, al-ijtihad al-intiqaʼi, al-ijtihad al-inshaʼi.
Why create SciArt? An investigation into science artists' goals and professional journeys
Authors: Fleerackers Alice , Brown Jarreau Paige , Krolik Julia
Published: October 2022

Although Science Art (“SciArt”) is increasingly used in science communication as a way to make content more engaging or accessible, little is known about why artists pursue this practice or what they hope to achieve through their work. This project addresses these questions through a thematic analysis of interviews with 131 practicing science artists. We identify a diversity of goals for creating SciArt, only some of which involve communicating science.
Clinical efficacy and safety of ivermectin (400 ug/kg, single dose) in patients with severe COVID-19: a randomized clinical trial
Authors: Ochoa-Jaramillo Francisco , Rodriguez-Vega Federico , Cardona-Castro Nora , Posada-Velez Veronica , Rojas-Gualdron Diego , Contreras-Martinez Heidy , Romero-Millan Ana , Porras-Mansilla Jessica
Published: October 2022

Purpose: To evaluate the clinical efficacy of including Ivermectin (single dose on day 1 of 400 ug/kg PO) in the standard of care in hospitalized adults with severe COVID-19. Methods: Double-blinded, parallel, placebo-controlled, single-center, randomized clinical trial. Seventy-five patients were randomly assigned (1:1) to receive standard of care plus ivermectin or placebo and were followed up for 21 days. Primary outcome measure was admission to ICU and secondary outcomes were the requirement of intensive mechanical ventilation (IMV) and in-hospital death. Intention-to-treat analyses, estimated risk differences (RD), and Hazard ratios (HR) with Cox regression were performed. Results: Enrollment stopped due to the lack of eligible patients. Thirty-seven patients were assigned to intervention and 38 to placebo. Patients in the ivermectin group were 54.5 years on average, 62.2% were male. Comorbidities were more prevalent in the control group (78.9% vs. 56.8%). There was no difference in the 21-day risk of admission to the ICU between ivermectin (21.6%) and placebo (15.8%) (RD= 5.8%; 95%CI: -11.8%-23.5%); neither in the risk of requirement of IMV (18.9% vs 13.2%), mortality (5.4% vs 10.5%) or in adverse events (32.4% vs. 28.9%). Discussion: Ivermectin showed no significant benefit in reducing the requirement of ICU, IMV, or mortality for severe COVID-19 patients.
Saudi Arabia’s City Ranking Index (SACRI) methodology executed: Preliminary findings
Authors:   Center for Population Studies King Saud University Riyadh, Saudi Arabia, Al-Khraif Rshood M. , Elsegaey Ibrahim ,   Center for Population Studies King Saud University Riyadh, Saudi Arabia, Al-Mogarry Mohamed ,   Department of Geography, King Saud University, Faculty of Arts Riyadh, Saudi Arabia, Salam Asharaf Abdul ,   Center for Population Studies King Saud University Riyadh, Saudi Arabia
Published: October 2022

Aim/purpose – Saudi Arabia is rapidly urbanizing, where the number of urban residents, currently exceeds 80% of the population. Many cities in the country face challenges of sustainability, livability, resilience, and thus global reputation. Therefore, measuring city performance is crucial in assessing urban complexity in order to improve development potential. As stated in Vision 2030 of the Kingdom of Saudi Arabia, attempts at improv- ing the global competitiveness and reputation of cities are of prime importance. This attempt aims at developing a culturally sensitive city ranking methodology, testing the method with relevant statistics, and presenting the preliminary results for further discus- sions, deliberations, and extensions. Design/methodology/approach – In this context, an index named Saudi Arabia’s City- -Ranking Index (SACRI) was developed, which proposes a three-dimensional assess- ment, incorporating livability, competitiveness, and environmental sustainability with 58 indicators (widely used or culturally specific). This exercise is carried out in 17 future cities, considering the feasibility criterion. Findings – Riyadh emerged as the most preferred city with the first rank, followed by Jeddah, Dammam, Madina, and Al Baha in order. Najran ranks 17, the last, preceded by Jazan, Al Qatif, Arar, and Al Taif. Research implications/limitations – This ranking of Saudi Arabia’s cities seeks im- portance in planning, improving, and promoting livability, competitiveness, and envi- ronmental sustainability to grab prominent places on a global scale. Originality/value/contribution – This exercise is unique for Saudi Arabia, with specific cultural dimensions that could be replicated in the neighboring Arab countries. Keywords: city ranking, urbanization, livability, competitiveness, environmental sus- tainability. JEL Classification: J10.
THE FORMATION OF ETHICAL CONCEPTS ON THE IMPOSITION OF LIFE IMPRISONMENT IN THE MODERN PERIOD
Authors:   Central Russian Institute of Management, branch of RANEPA, BATSUKIN A.A. , KUZNETSOVA E.V. ,   Central Russian Institute of Management, branch of RANEPA
Published: October 2022

The purpose of the article is to analyze the emer-gence of ethical concepts on the imposition of life imprisonment in Russia. The author makes a histori-cal and legal review. Much attention is given to the legal ethics in rela-tion to imposition of life imprisonment. The authors emphasized that they faces with the internal and external side of this punishment. First, the authors prove that the imposition of such severe punishment changes not only the personality of the prisoner, but also his psychophysical state. Second, the public attitude to this measure of punishment is also ambig-uous. The author point out that the imposition of life imprisonment has a long history; the imposition of life imprisonment is now the most severe punishment due to the refusal of the death penalty. As a result, the authors draw a conclusion that the analysis shows the subordination of law to morality, which leads to the destruction of general concepts on the imposition of life imprisonment.
THE 6TH RIFLE DIVISION IN 1943 – A PARTICIPATION IN THE RADICAL TURNING POINT IN THE GREAT PATRIOTIC WAR
Authors:   Central Russian Institute of Management, branch of RANEPA, SHESTAKOV A.A.
Published: October 2022

The purpose of the article is to study the processes of formation and development of the 6th Rifle division in 1918-1943 and its participation in the Great Patriotic War in 1943. The dynamics of the division's structure, its command and political and personnel stuff, its dynamics and moral and political conditions, armament, subordination, combat work during 1943, including participation in the Kharkov defensive operation in February-March 1943, political work on the decomposition of enemy troops are studied.
A Competitividade Brasileira Recente no Mercado Externo
Authors: Schettini Daniela , Gumiero Camila
Published: October 2022

No atual cenário brasileiro de estagnação econômica, pós o ciclo de crescimento econômico observado durante a década de 2000, a competitividade externa e a produtividade das atividades econômicas voltam ao debate econômico como um importante fator para a construção de sólido crescimento econômico de longo prazo. O artigo compara o Brasil com seus principais competidores no mercado internacional, analisando os fatores estruturais que sustentam a competitividade de um país, como infraestrutura, educação, saúde, tecnologia e o próprio ambiente de negócios. Os resultados mostram que para o Brasil avançar na competitividade, especialmente em relação aos seus concorrentes diretos, precisa melhorar sua infraestrutura logística e a educação de sua população.
Convergência espacial da criminalidade nas microrregiões do Nordeste brasileiro
Authors: Souza Helson Gomes de , Rocha Stalys Ferreira , Chaves Fellipy Augusto Holanda
Published: October 2022

O presente trabalho tem como objetivo verificar a veracidade da hipótese de convergência para os níveis de criminalidade nas microrregiões do Nordeste brasileiro. Para tanto, foram utilizados dados para 187 microrregiões do Nordeste do Brasil, distribuídos entre os anos de 1996 a 2015. Por meio de uma metodologia espacial para dados em painel, concluiu-se que as taxas de criminalidade das microrregiões do Nordeste brasileiro convergem para uma determinada taxa de equilíbrio. Além disso, foi possível concluir que essa convergência ocorre a uma velocidade relativamente baixa, onde seriam necessários cerca de 35 anos para que essa taxa de equilíbrio fosse alcançada.
O TRANSBORDAMENTO ESPACIAL NA ESTRATÉGIA SAÚDE DA FAMÍLIA DE 1998 A 2012
Authors: Gomes Bruno Silva de Moraes , Bastos Suzana Quinet de Andrade , Almeida Eduardo Simões de
Published: October 2022

O artigo analisa as questões espaciais da Estratégia Saúde da Família (ESF) capazes de influenciar a taxa de mortalidade infantil nos municípios brasileiros entre 1998 e 2012. Utiliza como metodologia o modelo de dados em painel espacial. O trabalho inova ao considerar o espraiamento da cobertura da equipe saúde da família para os municípios vizinhos. Como resultado, observa a presença dos efeitos do tipo feedback, em que os efeitos diretos da ESF passam para os vizinhos e retornam, e o espraiamento da razão de cobertura dos vizinhos na redução da mortalidade infantil. Conclui-se que um aumento da ESF em um município reduz a taxa de mortalidade infantil nos vizinhos.
As elasticidades da demanda por veículos novos no Brasil: Uma análise considerando o preço dos veículos usados
Authors: Nicolay Rodolfo , Jesus Danilo
Published: October 2022

Esse trabalho analisa o comportamento da demanda por veículos novos no Brasil. A contribuição deste trabalho reside na inclusão do preço do veículo usado na análise. Ademais, utilizamos uma variável qualitativa para captar a eficácia da política anticíclica implementada pelo governo brasileiro durante a crise do subprime. As elasticidades são estimadas usando-se uma base de dados mensal e análise empíricas estatísticas robustas por meio do Método de Defasagens Autoregressivas Distribuídas (ARDL). Os resultados obtidos neste trabalho indicam que a demanda por veículos novos no Brasil é elástica em relação aos preços dos veículos usados e que o veículo usado é um bem substituto perfeito do veículo novo. Ademais, os resultados também indicam que a política anticíclica aplicada durante a crise foi efetiva para elevar o nível de demanda por novos veículos.
Efeito da fecundidade sobre a criminalidade no estado de São Paulo
Authors: Barbosa Miriã Ramalho , Teixeira Evandro Camargos
Published: October 2022

Este trabalho tem como objetivo analisar o efeito da fecundidade, representada pela taxa de fecundidade geral no período 1995-2002, sobre a taxa de roubos por 100.000 habitantes entre os anos de 2010 e 2017 no estado de São Paulo. Para tal, utilizou-se um modelo econométrico com dados em painel dinâmico. Os resultados indicam que a taxa de fecundidade geral impacta positivamente na evolução da taxa de roubos de forma defasada, ou seja, 15 anos depois. Nesse sentido, políticas públicas capazes de elevar a escolaridade das mulheres, particularmente das adolescentes, e consequentemente diminuir a fecundidade atual podem ser arrefecedoras da criminalidade futura.
Evidências sobre o impacto da maternidade no mercado de trabalho brasileiro, 1995-2015
Authors: Rosa Ana Maria Paula , Cunha Marina Silva da , Vasconcelos Marcos Roberto
Published: October 2022

O presente trabalho tem como objetivo analisar os efeitos da maternidade no mercado de trabalho brasileiro de 1995 até 2015. Como metodologia, foram adotadas estimações de equações de rendimentos e da decomposição de Oaxaca-Blinder com a fonte de dados da Pesquisa Nacional por Amostra de Domicílios (PNAD) do Instituto Brasileiro de Geografia e Estatística (IBGE). Os resultados evidenciam que os efeitos da maternidade na participação da mulher no mercado de trabalho são negativos e decrescentes ao longo do período estudado. Já os diferenciais de rendimentos entre as mulheres com filhos e aquelas sem filhos são negativos e crescentes para as mães. Isso é indicativo da presença de uma penalidade para a maternidade no Brasil, tanto em relação à inserção no mercado laboral quanto nos rendimentos.
Análise econômica do Direito: o Direito como instrumento para o desenvolvimento econômico
Authors: Lisbinski Fernanda Cigainski , Pereira Adriano José , Neves Ednalva Felix das
Published: October 2022

O presente estudo visa apresentar ao leitor à Análise Econômica do Direito, como instrumento utilizado para o desenvolvimento econômico. Nesse sentido, seu objetivo é analisar a economia do direito e a sua atuação como instrumento no desenvolvimento de uma economia. Para isso, utilizou-se da análise bibliográfica apresentando doutrinas que fundamentam a pesquisa. Assim, verifica-se que o direito atua por meio de regras e normas que determinam padrões de comportamentos que limitam a atuação dos indivíduos e garantem o direito à propriedade e a segurança nas relações contratuais. Além disso, é por meio do direito que o Estado define direitos e obrigações para os agentes e cria instituições, proporcionando maior segurança para investimentos, o que acarreta no crescimento e desenvolvimento econômico de um país.
Regulação Bancária no Brasil: um estudo da sua (Trans)formação
Authors: Nappi Joseli Fernanda , Silva de Deos Simone , Ribeiro de Mendonça Ana Rosa , Bullio Mattos Olívia Maria
Published: October 2022

O objetivo deste trabalho é resgatar a formação e as transformações da estrutura regulatória do sistema bancário brasileiro desde o seu surgimento até o período que precede a adoção das normas internacionais de Basileia no país (1808-1994). Para o seu desenvolvimento foi realizada pesquisa bibliográfica e pesquisa documental direta, através da análise de documentos oficiais do Banco Central do Brasil, Conselho Monetário Nacional e Comitê de Basileia. A partir da pesquisa pode-se concluir que desde a sua origem, o sistema bancário nacional possui um aparato regulatório marcado por regras prudenciais e de uma rede de segurança. Além disso, verificou-se que a formação e as transformações do sistema bancário e do aparato regulatório aconteceram de forma simultânea, evidenciando o pressuposto assumido. Nesse sentido, no início da década de 1990 o quadro regulatório nacional podia ser considerado relativamente complexo, no sentido de contar com a participação de diversos agentes e instrumentos. Portanto, a própria adoção de Basileia no país deve ser entendida dentro de um movimento internacional mais amplo, que buscava homogeneizar as regras num momento de aprofundamento da abertura externa da economia e do sistema bancário brasileiro.
Os possíveis impactos das novas regras previdenciárias propostas na PEC 287/2016 para o envelhecimento da força de trabalho brasileira
Authors: Moreira Cássio Silva , Nulle Andressa Lopes
Published: October 2022

Considerando a amplitude da Proposta de Emenda Constitucional 287/2016 que tramitou no Congresso Nacional, o objetivo principal deste estudo é identificar seus possíveis impactos, da Reforma proposta para o envelhecimento da força de trabalho brasileira. Ademais, buscou-se explorar o dilema do sistema previdenciário quanto à sua sustentabilidade e às regras que estão sendo impostas. Para a obtenção dos dados, realizaram-se pesquisas bibliográficas e documentais por meio da contribuição de autores favoráveis e contrários à reforma. A partir das conclusões, demonstra-se que as implicações para os trabalhadores vão além da restrição ao acesso dos benefícios previdenciários, recaindo sobre a questão da empregabilidade dos mais velhos no mercado de trabalho. Para o setor empresarial, a reforma previdenciária tende a afetar a área de gestão de pessoas, podendo haver conflitos entre a priorização de ações que visem ao controle de custos versus a necessidade de promover a qualidade de vida no trabalho.
New records of Branchiostoma californiense (Amphioxiformes: Branchiostomatidae) in El Salvador, Central America
Authors: Barraza José Enrique , Melara Pérez Verónica Esperanza
Published: October 2022

Introduction: Cephalochordates are benthic organisms that represent an important link in the evolution of chordates. Coastal human communities use them as food in some Asian countries. Objective: To register the presence of B. californiense in El Salvador. Methods: We collected specimens during different benthic surveys at Jiquilisco and La Union Bays in April 2018 and November 2019, with a Petite Ponar grab and core in subtidal as well as intertidal sediments, respectively. Results: Ten specimens were collected from sandy-muddy sediments at Jiquilisco and La Union bays. Conclusion: B. californiense inhabits estuarine areas in El Salvador.
Spatial-temporal evolution of habitat quality in typical ecologically fragile areas of western China over the past 40 years: A case study of the Ningxia Hui Autonomous Region
Authors: Wang Ding , Hao Haiguang , Sun Lihui , Liu Hao , Li Yuyang
Published: October 2022

We use the InVEST model and five periods of land use data from 1980 to
2020 to assess the habitat quality of the Ningxia Hui Autonomous Region
in western China, which has characteristics of a typical fragile
ecosystem. We further analyze the spatial and temporal characteristics
of habitat quality evolution and its relationship with land use and
landscape pattern indices to explore the close relationship between
regional habitat quality changes and human natural resource conservation
and utilization.The research results show that the overall habitat
quality of Ningxia Hui Autonomous Region was stable and at a moderate
level during the 40 years from 1980 to 2020; Habitat patches with low,
high and very high quality occupy a larger proportion of the area,
followed by very low and moderate levels. There was a significant
spatial aggregation of high and low habitat quality in Ningxia, with
high values usually distributed in the northern and southern areas with
good natural conditions and low values distributed in areas with
frequent human activities and poor natural conditions. The decrease in
habitat quality in Ningxia was mainly due to the expansion of cultivated
land and construction land, the increase in landscape fragmentation and
the resulting decrease in connectivity. On the other hand, due to the
implementation of ecological protection measures, such as the project of
returning farmland to pasture and grass to forest, the quality of
habitats in Ningxia increased. The conclusions of this study support the
idea that the conservation of habitat quality in ecologically fragile
areas should fully preserve the original natural habitats and reduce the
interference of human activities. At the same time, targeted ecological
protection policies should be developed to restore the areas where the
habitat quality has been damaged and ultimately maintain the stability
of biodiversity and ecosystems in ecologically fragile areas.
Prenatal antibiotic exposure and the risk of atopic dermatitis in children: a nationwide population-based cohort study.
Authors: Chang Yu Chuan , Wu Meng-Che , Wu Hsing-Ju , Liao Pei-Lun , Wei James
Published: October 2022

Background: Atopic dermatitis (AD) contributes to substantial
social and financial costs in public health care systems. Antibiotic
exposure during pregnancy has been proposed as a risk factor, but
findings remain inconsistent. The aim of this study was to investigate
the association between prenatal antibiotic use and childhood AD.
Methods: We performed a population-based cohort study using
data collected from the Taiwan Maternal and Child Health Database from
2009 to 2016. Associations were determined using Cox proportional
hazards model and were adjusted for several potential covariates,
including maternal atopic disorders and gestational infections. Subgroup
analyses evaluated the influence of postnatal infant
antibiotic/acetaminophen use on the association between prenatal
antibiotic exposure and childhood AD diagnosed after 1 year of age.
Results: A total of 1288343 mother-child pairs were identified
and 39.5% received antibiotics prenatally. Maternal antibiotic use
during pregnancy was slightly positively associated with childhood AD
(aHR 1.05, 95% CI 1.04-1.06), especially in the first and second
trimesters. An apparent dose-response pattern was observed with an 11%
increased risk when the exposure was ≥5 courses prenatally (aHR 1.11,
95% CI 1.09-1.14). Subgroup analysis showed the positive association
remained significant regardless of postnatal antibiotic use; however, a
negative association was found in children without postnatal infant
acetaminophen use (aHR 1.02, 95% CI 0.97-1.07). Conclusion:
Maternal antibiotic use during pregnancy was associated with increased
risk of childhood AD in a dose-related manner. Possible confounders
existed between prenatal antibiotics and postnatal infant acetaminophen
use in the subgroup analysis. Further research may be warranted to
investigate this variable using a prospectively designed study, and also
to examine whether or not this association is specifically related to
pregnancy.
Reviewing The Lorentz Factor In Terms of Heisenberg's Uncertainty Principle: The Uniqueness of The Velocity Vector and Time Perception
Authors: Doruköz Ulaş
Published: October 2022

In this article, the Lorentz Factor is reviewed in terms of Heisenberg’s Uncertainty Principle in the light of Einstein’s relativity equations. It is shown that the relative speed between any two objects in Space can not be zero under any circumstances. Therefore the Lorentz Factor can never be equal to 1. And the velocity vector of an object is unique with respect to any reference frame. These provide a new perspective to improve the general understanding about some basic concepts of Physics including relative motion, time and distance perception, exclusion principle, attributes of an object, volume, singularities, particle-wave duality and the nature of light which are discussed in the paper.
CLINICAL QUALITY MEASUREMENT AND EVALUATION SYSTEM IN TURKEY
Authors: AKSOY Hilal
Published: October 2022

I want to inform the readers about clinical quality measurement and
evaluation system in Turkey. The aim of the systemis monitoring the
health-cases with indicators based on process and result. The programme
was first initiated in 2012. The programme is still in developing
process to gain better information about clinical quality from the
healthcare institutions.
Research on Transformer Fault Diagnosis with the application of Improved Manta Ray Foraging Optimization Algorithm optimizing Back-Propagation Network based on Orthogonal Experiment
Authors: ZHANG YING , XU Longwu , FENG Chujie
Published: October 2022

Oil-immersed transformers will inevitably have various latent faults
during the ageing process, therefore, it is very important to correctly
diagnose the status of the transformer in a timely manner. The
traditional three-ratio method based on dissolved gas analysis (DGA)
data has an insufficient coding problem, limiting the effect of fault
diagnosis. To solve this problem, an improved manta ray foraging
optimization (MRFO) algorithm is proposed to optimize the fault
diagnosis model of the Back-Propagation (BP) Network in this paper. This
improved algorithm primarily uses a multi-stage algorithm that combines
logical mapping and opposition based learning (OBL) to provide the
initial position for the MRFO to strengthen the global optimization
ability of the algorithm. Meanwhile, three foraging strategies of
modified MRFO algorithm by using the orthogonal experiment method are
proposed, to adjust the exploration and development of the manta ray
individual, so as to strengthen the optimization ability of the
algorithm on specific problems. As the result, the optimal solution
obtained by the improved MRFO algorithm is given to the weights and
biases of the BP network, and a transformer fault diagnosis system is
established. In addition, experiments are carried out using IEC TC 10
fault data, and the experimental results are compared with algorithms.
Comparative analysis and experimental results show that the accuracy of
this improved algorithm is 16%, 8%, and 24% higher than the results
of Back Propagation Neural Network(BP), unimproved Manta ray foraging
optimization combined with Back Propagation Neural Network(MRFO -BP),
and the three-ratio method, respectively
Health professions education in Serbia: Evaluation and measures for quality improvement through experiential education, interprofessional education and teaching competencies development
Authors: Kovacevic Milena , Odalovic Marina , Djukic-Cosic Danijela , Vasiljevic Dragana , Parojcic Jelena , Tasic Ljiljana
Published: October 2022

Background/Aim. Health professions education is facing emerging issues. A comprehensive situation analysis was performed among academic staff, healthcare practitioners, and healthcare science students to address and respond to new trends. The aim of the study was to investigate the attitude, perception, and the recognized needs towards experiential education (EE), interprofessional education (IPE), and teaching competencies development (TCD). The critical evaluation of the existing quality standards for further quality improvement in health professions education in Serbia was provided. Methods. The survey on EE, IPE, and TCD was conducted within the Reinforcement of the Framework for Experiential Education in Serbia (ReFEEHS) project, co-funded by the Erasmus+ program of the European Comission at four Serbian universities (the University of Belgrade, the University of Kragujevac, the University of Nis, and the University of Novi Sad). Four task groups were appointed to perform a desk review of the existing curricula, recommendations, and practices within each of the four health professions education (Medicine, Pharmacy, Dentistry, and Nursing) in Serbia and assess the level of compliance with relevant educational policies and practices in the European Union. Results. A total of 1,507 respondents completed the survey. A highly expressed positive attitude was found towards EE, IPE, and TCD among all the respondents. The majority of the respondents (> 70%) shared that EE should be organized in real-life practice and involve students? work under the supervision of a qualified supervisor, as well as interactions with patients and healthcare professionals. About 90% of the respondents supported the inclusion of IPE teaching activities into EE, with 77% of students expressing high motivation to attend those classes, whereas 93% of academic staff was eager to deliver and teach joint IPE subjects. Only 20% of academic staff has already attended some TCD program, while 75% recognized the need for its organization. Moreover, 90% of healthcare practitioners have recognized that mentors/clinical supervisors also need additional skills for effective mentoring work within health science education. Based on the survey results, recommendations for improvement were given within three educational fields, healthcare science curricula, professional practice (traineeship), teaching staff, and regulations. Conclusion. The results derived from the survey served as a starting but also a vital point for higher education improvement in Serbia. All interested parties ? academia, students, healthcare professionals, and regulatory bodies should collaborate on achieving improved, contemporary, and transformative health professions education.
Pharmacologic Treatment of Type 2 Diabetes in the U.S., Sweden, and Israel
Authors: Lyu Beini , Sang Yingying , Selvin Elizabeth , Chang Alex R. , Alexander G. Caleb , Cohen Cheli Melzer , Coresh Josef , Shalev Varda , Chodick Gabriel , Karasik Avraham , Carrero Juan-Jesus , Fu Edouard L. , Xu Yang , Grams Morgan E. , Shin Jung-Im
Published: October 2022

OBJECTIVE

To characterize and compare glucose-lowering medication use in type 2 diabetes in the U.S., Sweden, and Israel, including adoption of newer medications and prescribing patterns.

RESEARCH DESIGN AND METHODS

We used data from the National Health and Nutrition Examination Survey (NHANES) from the U.S., the Stockholm CREAtinine Measurements (SCREAM) project from Sweden, and Maccabi Healthcare Services (Maccabi) from Israel. Specific pharmacotherapy for type 2 diabetes between 2007 and 2018 was examined.

RESULTS

Use of glucose-lowering medications among patients with type 2 diabetes was substantially lower in NHANES and SCREAM than in Maccabi (66.0% in NHANES, 68.4% in SCREAM, and 88.1% in Maccabi in 2017–2018). Among patients who took at least one glucose-lowering medication in 2017–2018, metformin use was also lower in NHANES and SCREAM (74.1% in NHANES, 75.9% in SCREAM, and 92.6% in Maccabi) whereas sulfonylureas use was greater in NHANES (31.5% in NHANES, 16.0% in SCREAM, and 14.9% in Maccabi). Adoption of dipeptidyl peptidase 4 inhibitors and sodium–glucose cotransporter 2 inhibitors (SGLT2i) was slower in NHANES and SCREAM than in Maccabi. History of atherosclerotic cardiovascular disease, heart failure, reduced kidney function, or albuminuria was not consistently associated with greater use of SGLT2i or glucagon-like peptide 1 receptor agonists (GLP1RA) across the three countries.

CONCLUSIONS

There were substantial differences in real-world use of glucose-lowering medications across the U.S., Sweden, and Israel, with more optimal pharmacologic management in Israel. Variation in access to care and medication cost across countries may have contributed to these differences. SGLT2i and GLP1RA use in patients at high risk was limited in all three countries during this time period.
Contagious Itch, Disgust and Empathy in a Family with Scabies and their Treating Medical Staff: An Exploratory Study
Authors: Sutter Mia , Kamber Marise , Navarini Alexander , Mueller Simon M.
Published: October 2022

Abstract is missing (Short communication)
OPTIMAL CONTROL OF THE PRODUCTION SYSTEM BASED ON A PROBABILISTIC CRITERION
Authors: AKHMEDYANOVA GULNARA F. , PISHCHUKHIN ALEKSANDR M.
Published: October 2022

The article focuses on the probabilistic description of the company following the market demand. Both the market and the behavior of the enterprise are described applying the Fokker-Plank-Kolmogorov equation. The paper raises and solves the problem of optimal enterprise management. As a criterion, the authors consider the difference between the probability densities of the enterprise product demand in the market and the probability of releasing products to meet this demand. A coordinate-parametric approach to management is used. To find approximate solutions, the small parameter method is applied.
SOME ASPECTS OF THE PRESCHOOL CHILDREN’S EMOTIONAL DISTRESS PROBLEM
Authors: BELKINA VALENTINA N. , SHKATOVA TATIANA G.
Published: October 2022

The article considers one of the problems of modern childhood - the emotional distress of a child. According to the authors of the article, the most striking manifestations of the problem are aggression and anxiety, as two interrelated types of the children’s emotional sphere deformation. The authors discuss basic concepts, analyze the factors of aggression and anxiety development, and present a short list of emotional distress forms in preschool children. Some age and gender-role features of children's aggression and anxiety are also considered.
ORGANIZATION OF VOCATIONAL GUIDANCE WORK WITH SCHOOLCHILDREN IN A GENERAL EDUCATION INSTITUTION
Authors: DRYANNYKH NATALYA V. , KOROLEVA ANNA N. , RAKOVA SVETLANA S.
Published: October 2022

The authors consider various approaches to the concept of “vocational guidance” and the problem of organizing vocational guidance work with students in a general education institution. The article describes the experimental results obtained from the surveys of assessing schoolchildren satisfaction with career guidance work in grades 10-11 carried out in Vologda municipal general education institution “Secondary General School № 9”.
SUPPLEMENT TO HIGHER EDUCATION CONTENT AS ONE OF THE CONDITIONS FOR THE DEVELOPMENT OF SPECIALISTS' PROFESSIONAL CULTURE IN THE FIELD OF PHYSICAL TRAINING AND SPORTS
Authors: SKLYAR MAKSIM S.
Published: October 2022

The article focuses on the need to identify organizational and pedagogical conditions for the development of specialists' professional culture in the field of physical training and sports. One of them is the supplement to higher education content by reflecting the constructs of professional culture in it. The author describes the ways to solve this problem: the development and introduction of the special course "Professional culture of specialists in the field of physical training and sports" into the professional training process focused on the development and improvement of the personal construct components.
ON THE PRECEDENT SPACE OF TEXTS OF MODERN RUSSIAN NATIONALISM
Authors: IVANOVA ELENA M.
Published: October 2022

The article deals with the nature of the precedent space of modern Russian nationalist discourse, which includes both the texts of nationalist-oriented youth organizations and the texts of the conservative, enlightened wing of Russian nationalism. The author analyses precedent constants that form the intertextual encyclopedia of this discourse type.
luto não reconhecido pela morte do animal de estimação
Authors: Lapa Dioni Mateus Kammer , Nogueira Maria Teresa Duarte
Published: October 2022

O objetivo desta pesquisa foi o de investigar a existência de impactos psicológicos resultantes do não reconhecimento do luto pela perda de um animal de estimação. Trata-se de um estudo de caso com uma abordagem qualitativa. A pesquisa foi desenvolvida na cidade de Canguçu, na região sul do estado do Rio Grande do Sul. Fizeram parte do estudo 5 pessoas do sexo feminino, com idades entre 30 e 60 anos, que tiveram a perda de um animal de estimação nos últimos 12 meses. Essa amostra foi escolhida de forma aleatória, oriunda dos cadastros de duas clínicas veterinárias do município. Todas as participantes foram convidadas ao estudo, autorizando através do termo de Consentimento Livre Esclarecido sua participação. Foi utilizada uma entrevista semiestruturada, a qual foi gravada e os áudios das mesmas foram transcritos, os dados obtidos foram analisados e divididos em categorias. Este estudo foi aprovado por comitê de ética em pesquisa. Os resultados obtidos evidenciam que, em relação ao reconhecimento social, ficou evidente a falta de empatia por parte da sociedade, não legitimando esse pesar. Notam-se alguns impactos significativos pelo não reconhecimento do luto, como isolamento, receio, tristeza, culpa, dor por esconder seu sofrimento e sentimento de incompreensão.
Como o inconsciente ‘trata’ o traumático do real?
Authors: Pacheco Filho Raul Albino
Published: October 2022

Resenha do livro SOLER, Colette (2021). Adventos do real: da angústia ao sintoma. 2ª ed. São Paulo, Aller. Edição Kindle.