bluuebunny/crossref_metadata_2025 huggingface dataset:
Sebaran Spasial Nitrat dan Fosfat Di Perairan Terumbu Karang Kabupaten Bone dan Kelayakannya Untuk Lokasi Pertumbuhan Karang
Authors: Suryadi Lalu Penta Sebri , Haris Abdul , Yanuarita Dewi
Published: July 2022

Nitrat dan posfat dibutuhkan oleh zooxhantella yang bersimbiosis dengan terumbu karang. Kadar nitrat dan fospat perairan dipengaruhi oleh aktifitas di daratan karena sumber utama nutriaen yang ada di perairan berasal dari daratan. Penelitian ini bertujuan untuk mengevaluasi distribusi spasial nitrat dan fospat perairan dan kelayakan perairan untuk mendukung pertumbuhan karang. Pengujian nitrat dan fospat dilakukan di laboratorium kualitas air FIKP UNHAS. Hasil penelitian menunjukkan bahwa kadar nitrat dan fospat perairan di perairan terumbu karang kabupaten bone tidak terpengaruh oleh jaraknya dengan daratan. Hasil penelitian juga menunjukkan bahwa kadar nitrat perairan melebihi baku mutu air laut sedangkan kadar fospat perairan masih dibawah baku mutu air laut. Kondisi oseongrafi seperti suhu, salinitas dan DO tidak berada dalam kisaran optimal, sedangkan kecerahan, kecepatan arus dan pH perairan masih dalam kondisi optimal dalam mendukung pertumbuhan karang.
The Reconstruction of High-Inherited Wealth in Minangkabau through Cash Waqf Movement
Authors: Eficandra Eficandra
Published: July 2022

The development and demands of modern life results in the decrease of role and existence of high-inherited wealth in Minangkabau. This fact requires a reconstruction of the development of high-inherited wealth in Minangkabau. One of them is through cash waqf movement which is an alternative in developing and empowering the people’s economy. This paper aims at explaining the reconstruction of high-inherited wealth in Minangkabau through the cash waqf movement. This study tried to offer solutions and alternatives in restoring the role and existence of high-inherited wealth in Minangkabau through the cash waqf movement. By using a qualitative approach, this study found that the cash waqf movement can restore the role and position of high-inherited wealth in Minangkabau in the following forms; first, returning or reclaiming the pawned assets and increase the number of assets through the cash waqf movement from all members of the tribe or clan. Second, striving for the legality of these assets by changing the certificate into waqf property. Third, managing the high-inherited assets productively and share the profits for the economic needs and welfare of the people or tribe. Assets management and development through the cash waqf movement can be used as a model for other communities, especially the Minangkabau community in managing people’s or tribal assets and improving the welfare of the people.
Angiomyolipomas of kidneys in children with tuberous sclerosis — current state of the problem
Authors:   Veltischev Research and Clinical Institute for Pediatrics, MOROZOV S. L. , PIRUZIEVA O. R. ,   Veltischev Research and Clinical Institute for Pediatrics, DOROFEEVA M. YU. ,   Veltischev Research and Clinical Institute for Pediatrics, TARASOVA O. V. ,   Pirogov Russian National Research Medical University, DLIN V. V. ,   Veltischev Research and Clinical Institute for Pediatrics
Published: July 2022

Tuberous sclerosis is a rare multisystem disease with autosomal dominant inheritance, characterized by the formation of hamartomas in many organs and tissues, including skin, brain, kidneys, lungs and heart, with a variety of clinical manifestations. One of the largest problems in patients with tuberous sclerosis is renal angiomyolipomas, which are the most common manifestation of the disease. An important point in the course of tuberous sclerosis with kidney damage is the formation of secondary complications that occur against the background of the underlying disease. The present review shows the relevance of the problem of angiomyolipomas in tuberous sclerosis, considers the pathogenesis of the disease, and presents the basic principles of treatment.
Imported cases of dengue fever among residents of the Republic of Tatarstan
Authors:   Kazan State Medical University, FAZULZYANOVA A. I. , TKACHEVA S. V. ,   Kazan State Medical University, SADYKOVA D. A. ,   Kazan State Medical University
Published: July 2022

The article presents an analysis of clinical-epidemiological and laboratory-instrumental data of 15 patients with dengue fever (DF), residents of the Republic of Tatarstan, who visited regions endemic for DF as tourists. To verify the diagnosis, PCR diagnostics of blood serum for dengue virus RNA and determination of dengue virus serotypes were carried out. The classical form of the disease of moderate severity was diagnosed in 14 (93.3%) patients. The clinical picture was characterized by an acute onset, fever, chills, myalgia, arthralgia. The total duration of the febrile period varied from 3 to 7 (4.1 (2.09)) days. In 7 (46.7%) patients, maculopapular exanthema of various localization was observed, in 43% it was hemorrhagic in nature and was accompanied by itching (28.6%). In 5 (33.3%) cases, dyspeptic syndrome developed. 4 (26.7%) patients were diagnosed with respiratory syndrome. Hematological changes were characterized by thrombocytopenia in 93.3% (105.6 (35.9) 109/l) and leukopenia in 86.7% (3.2 (1.9) 109/l) of patients. 7 (46.7%) patients had a moderate cytolytic syndrome with a predominance of ALT (61 (43.3) U/l) and AST (59.6 (36.9) U/l) activity in the early period of the disease. In 7 (46.7%) patients, an increase in the pulmonary pattern of both lungs with perivascular and peribronchial changes was diagnosed radiographically. Sonographic examination of the abdominal organs revealed an increase in the size of the liver and spleen in 3 (20%) patients. Thus, imported cases of DF in the Republic of Tatarstan were characterized by the development of the classical moderate form caused by serotypes 1-3. Due to the increased DF incidence in the Russian Federation and, in particular, in the Republic of Tatarstan, it is necessary to improve medical alertness in diagnosing the disease characterized by fever combined with arthralgia, myalgia and exanthema in people who returned from endemic countries. Due to the lack of vaccination in the Russian Federation, it is necessary to inform patients who recovered from DF about the risk of developing a hemorrhagic form of the disease in case of re-infection.
Drosophila as a Model for Microbiota Studies of Neurodegeneration
Authors: Kitani-Morii Fukiko , Friedland Robert P. , Yoshida Hideki , Mizuno Toshiki
Published: July 2022

Accumulating evidence show that the gut microbiota is deeply involved not only in host nutrient metabolism but also in immune function, endocrine regulation, and chronic disease. In neurodegenerative conditions such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis, the gut-brain axis, the bidirectional interaction between the brain and the gut, provides new route of pathological spread and potential therapeutic targets. Although studies of gut microbiota have been conducted mainly in mice, mammalian gut microbiota is highly diverse, complex, and sensitive to environmental changes. Drosophila melanogaster, a fruit fly, has many advantages as a laboratory animal: short life cycle, numerous and genetically homogenous offspring, less ethical concerns, availability of many genetic models, and low maintenance costs. Drosophila has a simpler gut microbiota than mammals and can be made to remain sterile or to have standardized gut microbiota by simple established methods. Research on the microbiota of Drosophila has revealed new molecules that regulate the brain-gut axis, and it has been shown that dysbiosis of the fly microbiota worsens lifespan, motor function, and neurodegeneration in AD and PD models. The results shown in fly studies represents a fundamental part of the immune and proteomic process involving gut-microbiota interactions that are highly conserved. Even though the fly’s gut microbiota are not simple mimics of humans, flies are a valuable system to learn the molecular mechanisms of how the gut microbiota affect host health and behavior.
The Role of the Gut Microbiota in the Metabolism of Polyphenols as Characterized by Gnotobiotic Mice
Authors: Pasinetti Giulio Maria , Singh Risham , Westfall Susan , Herman Francis , Faith Jeremiah , Ho Lap
Published: July 2022

A growing body of experimental data suggests that microbes in the gut influence behavior and can alter brain physiology and neurochemistry. Although promising, researchers are only starting to understand the potential of the gut microbiota for use in neurological disease. Recent evidence demonstrated that gastrointestinal activities are linked to mood disorders such as anxiety, depression, and most recently, cognitive functions in age-related neurodegenerative disorders. Studies from our group and others are uncovering new evidence suggesting that the gut microbiota plays a crucial role in the metabolism and bioavailability of certain dietary compounds and synthetic drugs. Based on this evidence, this review article will discuss the implications of the gut microbiota in mechanisms of bioavailability and biotransformation with an emphasis on dietary polyphenol compounds. This will be followed by a survey of ongoing innovative research identifying the ability of individual gut bacteria to enhance the bioavailability of gut-derived, brain-penetrating, bioactive polyphenol metabolites that ultimately influence mechanisms associated with the promotion of resilience against psychological and cognitive impairment in response to stress. Lastly, current research initiatives aimed at promoting the generation of brain bioactive polyphenol metabolites by specialized gut microbes will be discussed, specifically the use of gnotobiotic mice to develop bioengineered second generation probiotics. We propose that leveraging the gut microbial ecosystem to generate brain targeted bioactive metabolites from dietary polyphenols can attenuate lifestyle risk factors and promote resilience against age-related cognitive decline.
Gut Microbiota as a Hidden Player in the Pathogenesis of Alzheimer’s Disease
Authors: Choi Hyunjung , Lee Dongjoon , Mook-Jung Inhee
Published: July 2022

Alzheimer’s disease (AD), the most common neurodegenerative disorder, is accompanied by cognitive impairment and shows representative pathological features, including senile plaques and neurofibrillary tangles in the brain. Recent evidence suggests that several systemic changes outside the brain are associated with AD and may contribute to its pathogenesis. Among the factors that induce systemic changes in AD, the gut microbiota is increasingly drawing attention. Modulation of gut microbiome, along with continuous attempts to remove pathogenic proteins directly from the brain, is a viable strategy to cure AD. Seeking a holistic understanding of the pathways throughout the body that can affect the pathogenesis, rather than regarding AD solely as a brain disease, may be key to successful therapy. In this review, we focus on the role of the gut microbiota in causing systemic manifestations of AD. The review integrates recently emerging concepts and provides potential mechanisms about the involvement of the gut-brain axis in AD, ranging from gut permeability and inflammation to bacterial translocation and cross-seeding.
Investigating Casual Associations Among Gut Microbiota, Metabolites, and Neurodegenerative Diseases: A Mendelian Randomization Study
Authors: Ning Jing , Huang Shu-Yi , Chen Shi-Dong , Zhang Ya-Ru , Huang Yu-Yuan , Yu Jin-Tai
Published: July 2022

Background: Recent studies had explored that gut microbiota was associated with neurodegenerative diseases (including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS)) through the gut-brain axis, among which metabolic pathways played an important role. However, the underlying causality remained unclear. Objective: Our study aimed to evaluate potential causal relationships between gut microbiota, metabolites, and neurodegenerative diseases through Mendelian randomization (MR) approach. Methods: We selected genetic variants associated with gut microbiota traits (N = 18,340) and gut microbiota-derived metabolites (N = 7,824) from genome-wide association studies. Summary statistics of neurodegenerative diseases were obtained from IGAP (AD, 17,008 cases; 37,154 controls), IPDGC (PD, 37,688 cases; 141,779 controls), and IALSC (ALS, 20,806 cases; 59,804 controls) respectively. Results: Greater abundance of Ruminococcus (OR, 1.245; 95%CI, 1.103–1.405; p = 0.0004) was found significantly related to higher risk of ALS. Besides, our study found suggestive associations of Actinobacteria, Lactobacillaceae, Faecalibacterium, Ruminiclostridium, and Lachnoclostridium with AD, of Lentisphaerae, Lentisphaeria, Oxalobacteraceae, Victivallales, Bacillales, Eubacteriumhalliigroup, Anaerostipes, and Clostridiumsensustricto1 with PD, and of Lachnospira, Fusicatenibacter, Catenibacterium, and Ruminococcusgnavusgroup with ALS. Our study also revealed suggestive associations between 12 gut microbiome-dependent metabolites and neurodegenerative diseases. Glutamine was related to lower risk of AD. For the serotonin pathway, serotonin was found as a protective factor of PD, while kynurenine as a risk factor for ALS. Conclusion: Our study firstly applied a two-sample MR approach to detect causal relationships among gut microbiota, gut metabolites, and neurodegenerative diseases. Our findings may provide new targets for treatments and may offer valuable insights for further studies on the underlying mechanisms.
Can Better Management of Periodontal Disease Delay the Onset and Progression of Alzheimer’s Disease?
Authors: Harding Alice , Robinson Sarita , Crean StJohn , Singhrao Sim K.
Published: July 2022

A risk factor relationship exists between periodontal disease and Alzheimer’s disease (AD) via tooth loss, and improved memory following dental intervention. This links the microbial contribution from indigenous oral periodontal pathogens to the manifestation of chronic conditions, such as AD. Here, we use Porphyromonas gingivalis infection to illustrate its effect on mental health. P. gingivalis infection, in its primary sub-gingival niche, can cause polymicrobial synergy and dysbiosis. Dysbiosis describes the residency of select commensals from the oral cavity following co-aggregation around the dominant keystone pathogen, such as P. gingivalis, to gain greater virulence. The initial process involves P. gingivalis disturbing neutrophil mediated innate immune responses in the healthy gingivae and then downregulating adaptive immune cell differentiation and development to invade, and subsequently, establish new dysbiotic bacterial communities. Immune responses affect the host in general and functionally via dietary adjustments caused by tooth loss. Studies from animals orally infected with P. gingivalis confirm this bacterium can transmigrate to distant organ sites (the brain) and contribute toward peripheral and intracerebral inflammation, and compromise vascular and microvascular integrity. In another study, P. gingivalis infection caused sleep pattern disturbances by altering glial cell light/dark molecular clock activity, and this, in turn, can affect the clearance of danger associated molecular patterns, such as amyloid-β, via the glymphatic system. Since P. gingivalis can transmigrate to the brain and modulate organ-specific inflammatory innate and adaptive immune responses, this paper explores whether better management of indigenous periodontal bacteria could delay/prevent the onset and/or progression of dementia.
PESrank: An Explainable online password strength estimator1
Authors: David Liron , Wool Avishai
Published: July 2022

Human-chosen passwords are the dominant form of authentication systems. Passwords strength estimators are used to help users avoid picking weak passwords by predicting how many attempts a password cracker would need until it finds a given password. In this paper we propose a novel password strength estimator, called PESrank, which accurately models the behavior of a powerful password cracker. PESrank calculates the rank of a given password in an optimal descending order of likelihood. PESrank estimates a given password’s rank in fractions of a second – without actually enumerating the passwords – so it is practical for online use. It also has a training time that is drastically shorter than previous methods. Moreover, PESrank is efficiently tweakable to allow model personalization in fractions of a second, without the need to retrain the model; and it is explainable: it is able to provide information on why the password has its calculated rank, and gives the user insight on how to pick a better password. We implemented PESrank in Python and conducted an extensive evaluation study of it. We also integrated it into the registration page of a course at our university. Even with a model based on 905 million passwords, the response time was well under 1 second, with up to a 1-bit accuracy margin between the upper bound and the lower bound on the rank.
An experimental simulation testing of single-diode PV integrated mppt grid-tied optimized control using grey wolf algorithm
Authors: Babypriya B. , Renoald A. Johny , Shyamalagowri M. , Kannan R.
Published: July 2022

In the context of this paper a three phase grid connected Photo-Voltaic (PV) system that is used to design with MPPT and developed Grey Wolf optimization (GWO) algorithm for analyzing the power quality issues in the grid system. The proposed Grey Wolf optimization (GWO) algorithm is incorporated in the prototype model and compared with other related optimization algorithms namely Particle Swarm Optimization (PSO) and Genetic Algorithm (GA). The various loading conditions as well as solar irradiances are modeled by using MATLAB simulation and experimentally validated by a DSPIC (DS 1104) based prototype model. A three phase PV grid connected non-linear load is observed in different operating environmental conditions. The optimization control algorithms was developed and implemented in Super-Lift Inverter (SLI) grid connected system. The findings of this work are, grid reactive power demand is compensated using DSTATCOM, and also from the real power of renewable energy system. But, majority of the active power is provided or absorbed by DSTATCOM component. The objective of this proposed work is that the three optimization control algorithms are examined, and the PV integrated grid tied system maintains a compensation power at Unity Power Factor (UPF). The proposed optimization methods produce load output power factor values such as 0.89 (GWO), 0.88, (PSO) and 0.86 (GA).
A novel adaptive boundary weighted and synthetic minority oversampling algorithm for imbalanced datasets
Authors: Song Xudong , Chen Yilin , Liang Pan , Wan Xiaohui , Cui Yunxian
Published: July 2022

In recent years, imbalanced data learning has attracted a lot of attention from academia and industry as a new challenge. In order to solve the problems such as imbalances between and within classes, this paper proposes an adaptive boundary weighted synthetic minority oversampling algorithm (ABWSMO) for unbalanced datasets. ABWSMO calculates the sample space clustering density based on the distribution of the underlying data and the K-Means clustering algorithm, incorporates local weighting strategies and global weighting strategies to improve the SMOTE algorithm to generate data mechanisms that enhance the learning of important samples at the boundary of unbalanced data sets and avoid the traditional oversampling algorithm generate unnecessary noise. The effectiveness of this sampling algorithm in improving data imbalance is verified by experimentally comparing five traditional oversampling algorithms on 16 unbalanced ratio datasets and 3 classifiers in the UCI database.
Iron supplementation in pregnant Danish women revisited: Effects on prepartum and postpartum iron deficiency, anemia, serum erythropoietin; including iron status, erythropoietin and anthropometrics in newborns. A randomized, placebo-controlled study
Authors: Milman N. T.
Published: July 2022

OBJECTIVE: To assess effects of iron supplementation, 66 mg elemental iron daily as ferrous fumarate, on iron status markers during normal pregnancies. METHODS: Randomized, double-blind, placebo-controlled study of 119 women (62 iron-, 57 placebo -treated) and their newborns. Hemoglobin (Hb), serum (S)-ferritin, S-transferrin saturation percentage (TSAT) and S-erythropoietin (S-EPO) were measured at 14–18, 24–27 weeks of gestation, prepartum, 1 and 8 weeks postpartum. RESULT: From 24–27 weeks gestation to 8 weeks postpartum, the iron group had higher Hb, S-ferritin and TSAT than the placebo group; prepartum, 11% had iron deficiency (ID) and 0% iron deficiency anemia (IDA) in the iron group, vs 60% and 18% in the placebo group; 8 weeks postpartum 1.6% in the iron group had ID and 1.6% IDA vs 14% and 7% in the placebo group. S-EPO levels in the iron group were lower than in the placebo group (p < 0.001). Mothers prepartum S-EPO values were correlated to newborns cord S-EPO values (p < 0.001). Newborns to iron treated mothers had higher cord S-ferritin levels than those to placebo treated mothers (p = 0.02). Newborn girls had higher cord S-ferritin levels than boys (p < 0.01). There was no impact of iron supplementation on the length of gestation, placental weight, or newborns birth weight. Birth weight was correlated only with mothers’ body weight, length of gestation and placental weight. CONCLUSION: Iron supplementation had a “positive” impact on iron status and Hb both during pregnancy and postpartum, with a low frequency of ID/IDA and also a “positive” influence on newborns iron status.
ПОШИРЕННЯ ОКРЕМИХ ВАЖКИХ МЕТАЛІВ У ПОРОДАХ ТЕРИКОНА ЦЕНТРАЛЬНОЇ ЗБАГАЧУВАЛЬНОЇ ФАБРИКИ «ЧЕРВОНОГРАДСЬКА» ЛЬВІВСЬКО-ВОЛИНСЬКОГО КАМ’ЯНОВУГІЛЬНОГО БАСЕЙНУ
Authors: Kochmar I. М. , Karabyn V. V.
Published: July 2022

Породні відвали відходів вуглевидобування та вуглезбагачення спричиняють значне техногенне навантаження на території і становлять небезпеку для компонентів навколишнього природного середовища. Важкі метали, котрі концентруються у відходах вуглезбагачення, мають здатність мігрувати (вимиватися) у ґрунти та наземні і підземні води, накопичуватися рослинами в комплексі створюючи небезпеку для екосистеми. Дослідження були проведені з метою оцінки чинників екологічної небезпеки довкілля у зоні впливу породного відвалу Центральної збагачувальної фабрики «Червоноградська» Львівсько-Волинського кам’яновугільного басейну, спричинених розподілом різних форм окремих важких металів, а саме Co, Ni та Fe. В аргілітах, алевролітах, пісковиках, кременистому алевроліті визначені концентрації Co, Ni та Fe у валовій формі, ацетатно-амонійній та водній витяжках. Проаналізовано чинники екологічної небезпеки довкілля спричиненої розподілом різних форм кобальту, нікелю та заліза на основі встановлення міграційних можливостей цих елементів у зоні техногенезу. Перевищення ГДК валових форм досліджуваних важких металів не виявлено. Встановлені перевищення ГДК рухомих форм нікелю (ацетатно-амонійна витяжка) у алевроліті, пісковику та кременистому алевроліті (1,1 – 1,5 раза). Визначено коефіцієнти концентрації важких металів у досліджуваних пробах за відношенням до валової форми, у ацетатно-амонійній витяжці, які змінюються в діапазоні від 0,2170 у нікелі до 0,4032 у кобальті. Важкі метали, що концентруються у породах терикона, є малорухомими у водній витяжці і коефіцієнти концентрації знаходяться в межах від 0,0003 у залізі до 0,0232 у кобальті. Породи терикона ЦЗФ «Червоноградська» у частині поширення валових форм важких металів у породах є безпечними для довкілля, проте, у частині поширення рухомих форм Ni є небезпечними. Отримані дані та закономірності є важливим елементом розвитку теорії екологічної безпеки та теорії міграції хімічних елементів у зоні гіпергенезу.
IMPLEMENTASI BAURAN STRATEGI PEMASARAN PRODUK “MEAT” BERDASARKAN ANALISIS SWOT PADA PT DUA PUTRA PERKASA PRATAMA
Authors: Widiawati Kristiana , Miliniati Nada
Published: July 2022

ABSTRAK  Analisis SWOT merupakan salah satu strategi pemasaran yang sering diterapkan dalam perusahaan. Analisis SWOT menjadi bagian penting dalam menentukan strategi pemasaran yang efektif dan sangat dibutuhkan agar tercapainya penjualan produk yang menguntungkan. Analisis SWOT dapat dilihat dari kegunaan analisis SWOT, manfaat analisis SWOT, faktor-faktor analisis SWOT, product life cycle (PLC), penerapan analisis SWOT dan marketing mix. Tujuan penelitian ini adalah unutk mengetahu hasil analisa SWOT sebagai penentu strategi Pemasaran produk “meat” di PT Dua Putra Perkasa. Jenis data yang digunakan dalam penelitian adalah jenis data yaitu data primer dan data sekunder, data primer yang diambil dari wawancara sedangkan data sekunder adalah data yang diperoleh tidak langsung dari subjek penelitian itu sendiri. Teknik analasis yang dibunakan untuk mengolah data penelitian adalah kualitatif kualitataif deskriptif. Hasil penelitian analisis SWOT memiliki kegunaan sebagai alat mengukur besarmya potensi yang dimiliki perusahaan dan produk yang akan dijual serta untuk mengetahui sejauh mana perusahaan melihat lingkungan sekitar. Analisis SWOT mampu memberikan arahan untuk mempertahankan kekuatan, meminimalisir kelemahan dan menambah keuntungan dengan menambah peluang usaha yang tersedia. Kata Kunci: Analisis SWOT, Strategi Pemasaran, Faktor Internal, faktor eksternal  IMPLEMENTATION OF MARKETING STRATEGY MIX OF "MEAT" PRODUCT BASED ON SWOT ANALYSIS AT PT DUA PUTRA PERKASA PRATAMA  ABSTRACT  SWOT analysis is a marketing strategy that is often applied in companies. SWOT analysis is an important part in determining an effective marketing strategy and is very much needed in order to achieve profitable product sales. SWOT analysis can be seen from the usefulness of SWOT analysis, benefits of SWOT analysis, SWOT analysis factors, product life cycle (PLC), application of SWOT analysis and marketing mix. The purpose of this study is to find out the results of the SWOT analysis as a determinant of the marketing strategy of "meat" products at PT Dua Putra Perkasa. The type of data used in the study is the type of data, namely primary data and secondary data, primary data taken from interviews while secondary data is data obtained indirectly from the research subject itself. The analytical technique used to process research data is descriptive qualitative. The results of the SWOT analysis are useful as a tool to measure the potential of the company and the products to be sold and to find out how far the company sees the surrounding environment. SWOT analysis is able to provide direction to maintain strengths, minimize weaknesses and increase profits by increasing available business opportunities. Keywords: SWOT analysis, Marketing Strategy, Internal Factor, External Faktor
Pengaruh Leverage, Likuiditas, dan Ukuran Perusahaan Terhadap Profitabilitas Pada Perusahaan Textile dan Garment Yang Go Public Di Bursa Efek Indonesia
Authors: Nuraini Faradibah Desy , Suwaidi Rahman Amrullah
Published: July 2022

To get the maximum profit, the company must be able to compete with other companies and must improve the company’s performance in order to maximize the profit received. The aim of this study is to determine the effect of leverage, liquidity, and firm size on profitability. The dependent variable in this research is profitability and the independent variables are leverage, liquidity, and firm size. This research was conducted at textile and garment companies that went public on the Indonesia Stock Exchange during the 2016-2019 period. And with a total of 19 companies or population in this research. The sample in this study were 9 companies with a total of 36 data obtained using purposive sampling method and data analysis using multiple linear regression. The result of this study state that leverage has a negative and significant effect on profitability, liquidity has a positive and significant effect on profitability, and firm size has no and not significant effect on profitability.
Analisis Kinerja Manajerial Pada Bank Konvensional di Kota Lubuklinggau
Authors: Effendi Muhammad , Fitria Fitria , Syahrani Tiara
Published: July 2022

This research aims to find out how much influence the accounting control system, performance measurement system, reward system and decentralization on managerial performance on conventional banks in Lubuklinggau City. This research was conducted at all conventional banks in Lubuklinggau City. The population and sample in this study were managers or heads of conventional bank sections in Lubuklinggau City. The data used is primary data obtained from the results of the spread of questionnaires to managers or heads of conventional bank sections in Lubuklinggau City. The method used is multiple regression analysis. The data analysis technique used is quantitative descriptive with the help of THE SPSS program. From the test showed that the first hypothesis that the accounting control system affects manjerial performance is evidenced by a sig value of 0.046<0.005. Testing the second hypothesis showed that the performance measurement system had an effect on managerial performance, as evidenced by a sig value of 0.004<0.05. Testing the third hypothesis showed that the reward system had an effect on managerial performance, as evidenced by a sig value of 0.011<0.05. Testing the fourth hypothesis showed that the decentralized system of performance had an effect on managerial performance, as evidenced by a sig value of 0.002<0.05.
TINJAUAN HUKUM TERHADAP EFEKTIVITAS PEMUNGUTAN PAJAK KENDARAAN BERMOTOR PADA SAMSAT KABUPATEN TULUNGAGUNG
Authors: Mutaqien Denna Arief
Published: July 2022

Pajak daerah yang ditetapkan dalam bentuk undang-undang memiliki sifat memaksa karena memuat sanksi hokum berupa sanksi administrasi maupun sanksi pidana. Sekalipun pajak bersifat memaksa, pejabat pajak tidak boleh menyalahgunakan pajak yang dibayar oleh wajib pajak. Pajak yang ditetapkan dalam bentuk undang-undang pajak tidak boleh melepaskan kedua fungsi yang dimilikinya, yakni fungsi angaran maupun fungsi mengatur.

Rumusan masalah pada tesisini adalah:1) Bagaimanakah pelaksanaan pemungutan Pajak Kendaraan Bermotor di Kabupaten Tulungagung ?(2) Apakah factor penghambat pelaksanaan pemungutan Pajak Kendaraan Bermotor di Kabupaten Tulungagung ? (3) Bagaimanakah efektivitas pelaksanaan pemungutan Pajak Kendaraan Bermotor di KabupatenTulungagung gmenurut hukum ?

Jenis penelitian ini adalah penelitian hokum Empiris yang berangkat dari penelitian berlakunya Hukum yaitu penelitian hukum yang mengkaji perbandingan antara Realita Hukum dengan Idealnya Hukum.

Hasil penelitian ini adalah:(1) Pelaksanaan pemungutan Pajak Kendaraan Bermotor di KabupatenTulungagung sudah optimal. Hal ini terlihat dari tunggakan pajak kendaraan bermotor yang rendah pada kantor Samsat Tulungagung. Adapun pemungutannya dimulai dari pedaftaran, penetapan, pembayaran oleh wajib pajak dan pengesahan sampai pada penyetoran kekas daerah dengan dilaksanakan berdasarkan Peraturan Daerah Provinsi Jawa Timur, (2) Faktor penghambat pelaksanaan pemungutan Pajak Kendaraan Bermotor di Kabupaten Tulungagung adalah masih rendahnya kesadaran Wajib Pajak untuk melaksanakan kewajibannya membayar pajak, data wajib pajak yang tidak lengkap, pemindahtanganan kendaraan bermotor tanpa di baliknama; pemilik kendaraan perpindah tempat daerah lain, penarikan kendaraan bermotor dari pihak pembiayaan tanpa ada laporan dari pihak pemilik kendaraan bermotor ataupun dari pihak pembiayaan itu sendiri. (3) Efektivitas pelaksanaan pemungutan Pajak Kendaraan Bermotor di Kabupaten Tulungagung sudah efektif yang dapat diliat dari target realisasi penerimaan pajak kendaraan bermotor mencapai 102% walaupun masih ada kendala yang dihadapi oleh Kantor Samsat Tulungaagung yaitu masih rendahnya partisipasi wajib pajak dalam membayar pajak kendaraan bermotor tepat waktu sehingga masih banyak wajib pajak yang menunggak dalam membayar pajak kendaraan motor, oleh karena itu, perlu kesadaran dari masyarakat sendiri untuk membayar pajak kendaraan tepat waktu . Namun, dalam proses prosedur pembayaran pajak kendaraan bermotor sudah efektif karena tidak memerlukan waktu yang lama dalam pembaharuan pajak kendaraan bermotor itu sendiri.
LEGAL PROTECTION FOR E-WALLET CONSUMERS IN THE DIGITAL ECONOMY ERA
Authors: Kornelis Yudi
Published: July 2022

The era of digitalization seems to have influenced almost all human activities, including digital banking. By using electronic means, banks can now provide financial services to their customers without going through a physical office. Even today, digital-based financial services are presenting an electronic wallet/e-wallet. An E-wallet is a software-based product that uses internet signal, and Indonesia is starting to recognize it as a digital payment instrument. Implementing electronic money activities reduces cash circulation, referred to as a less-cash society, and makes payment efficient. In general, an e-wallet is an application based on a server, and using it requires a connection with the publisher first. However, the emergence of various kinds of e-wallets at this time is not a solution to reduce the problem but creates complaints on the usage. The current free-market era creates market competition and causes many business actors to only care about profit. Business actors mostly ignore the interests of consumers. Based on this condition, this research intends to deeply examine the legal protection form for e-wallet consumers in Indonesia. This study will use normative/doctrinal legal research methods to answer the existing problems. According to the Indonesian Consumer Protection Law, every e-wallet consumer has the right to get legal protection as a sense of security in making transactions. Consumers of e-wallets who received non-conformance services can sue for their losses legally through court or out of court under the Indonesian Consumer Protection Law provisions.
HARTA WARIS PADA PASANGAN YANG TIDAK MEMILIKI KETURUNAN MENURUT HUKUM ADAT BATAK TOBA
Authors: Ramadhana Widodo , S.O.R Lumbantoruan Sahala
Published: July 2022

Di Indonesia hukum waris masih merupakan hukum pluralisme (keberagam), hukum waris juga secara keseluruhan merupakan hukum perdata. Berdasarkan Pasal 1 ayat 3 Undang-Undang Dasar 1945 menyatakan bahwa Indonesia merupakan Negara Hukum. Hukum yang ada bersifat tertulis maupun tidak tertulis, Hukum yang tidak tertulis ini banyak sekali ditemui di Indonesia salah satunya ialah Hukum adat. Hukum adat Batak Toba ialah salah satu hukum yang hidup dalam masyarakat dengan sistem kekerabatannya mengikuti garis keturunan ayah (patrilineal) yang membedakan kedudukan anak laki-laki dan perempuan. Tujuan dari penelitian ini untuk mengetahui pembagian harta warisan terhadap pasangan yang tidakmemiliki keturunan menurut adat Batak Toba. Metode penelitian ini menggunakan cara ilmiah untuk mendapatkan data yang digunakan sebagai keperluan penelitian. Kesimpulan dari penelitian ini adalah Pembagian harta warisan pada pasangan yang tidak memiliki keturunan menurut hukum adat Batak Toba akan diberikan kepada bapak ataupun kakek dari pihak pewaris laki-laki, jika sudah tidak memiliki bapak atau kakek harta warisan berpindah kepada sanak kolateral yang disebut dengan panean (penanggung jawab)
ANALISIS STRATEGI PENGEMBANGAN KAMPUNG KEREN (KREATIF DAN INDEPENDEN) BERBASIS BUDAYA LOKAL SEBAGAI PROGRAM UNGGULAN PEMERINTAH KOTA KEDIRI MENUJU PARIWISATA PERKOTAAN
Authors: Nuril Huda Andy Bahtiar , Askafi Eka
Published: July 2022

The government provides more effective and efficient public services in the context of accelerating regional economic development through vision and mission, superior programs and activities directed at developing local potential according to the characteristics of the basic needs of the local community by taking into account the available resources that can be used as a mainstay sector to attract tourists from outside the area. The local government of Kediri City supports this effort with the flagship program of Kampung Keren (Creative and Independent). The research was carried out in the Kampung Dalem Village, Kediri City with the objectives of the research being (1) analyzing the types of regional superior product potential based on the type of marketing product entity, stakeholder participation, and marketing strategies in the Kampung Keren clusters, (2) analyzing the barriers to potential product development superior areas supporting the Kampung Keren clusters, (3) analyzing the causes of obstacles to the development of potential superior products from the areas supporting the Kampung Keren clusters, (4) analyzing SWOT-QSPM-based development strategies for regional superior products based on Kampung Keren clusters. The methodology is descriptive and the data is collected through discussion, documentation, and direct observation with 30 informants or respondents. The results of the study are 50 (fifty) potential local products that can be developed to support urban tourism based on the Kampung Keren cluster with various types of marketing product entities, especially services, with the largest community participation, and the level of promotion that must be more varied. The obstacles are especially in terms of limited budget and the main cause of the COVID-19 pandemic which requires the government to reallocate the budget for the development of Kampung Keren for prevention, handling and recovery of the economic impact of the COVID-19 pandemic. government stakeholders, entrepreneurs, citizens, media, academics, in providing participation in goods, money, thoughts, expertise, personnel.
DAMPAK FRAMING EFFECT DAN SELF EFFICACY DALAM PENGAMBILAN KEPUTUSAN INVESTASI (ANALISIS PROGRAM “MINI GOLD: SEMUA BISA PUNYA EMAS”)
Authors: Cahyanti Arovia Devi , Arisyahidin Arisyahidin , Talkah Abu
Published: July 2022

Investment decision making is inseparable from human behavior that allows for irrational behavior. The purpose of this study was to determine the effect of framing effect and self-efficacy on housewives' investment decisions. This study uses a quantitative approach. Methods of data collection using questionnaires and literature study. The populations in this study are housewives who live in the city of Kediri. Samples were taken as many as 50 respondents with special criteria, namely having investment experience. The research instrument test uses validity and reliability tests. The analysis prerequisite test used normality test, heteroscedasticity test and multicollinearity test. The data analysis technique used simple linear regression analysis.

The results of this study the framing effect variable has a significant influence on the investment decisions of housewives in Kediri City. Each change in the framing effect variable has an effect of 45.6% which has a real and positive effect on changes in the investment decision variable. This is in line with the theory that the Framing Effect consistently proves to be one of the biggest biases in decision making. The self-efficacy variable has a significant influence on the investment decisions of housewives in Kediri City. Each change in the self-efficacy variable has an effect of 77.4% which has a real and positive effect on changes in the investment decision variable. This is in accordance with the theory of financial self-efficacy, namely individuals who have a higher sense of self-control can solve financial problems or with a view of "problems to be solved, rather than threats to be avoided".
PENGARUH KEPEMIMPINAN DAN KOMPENSASI TERHADAP DISIPLIN KERJA KARYAWAN PT. SHELTER NUSANTARA
Authors: Mubarok Dwiki Hisyamul , Irbayuni Sulastri
Published: July 2022

This study aims to determine the effect of leadership and compensation on the work discipline of employees of PT. Shelter Nusantara. The population of this study were employees of PT. Shelter Nusantara, which amounts to 119. The sampling technique in this study used a simple random sampling technique using the Slovin formula, from the results of the calculation of the slovin formula, a sample of 54 respondents was obtained. The analytical technique used in this study is to use the Partial Least Square (PLS) application. According to the results of the study, it was found that: 1) Leadership has a contribution to work discipline, which means that the better the leadership in a company, the better the work discipline in the company. 2) Compensation has a contribution to work discipline, which means that the better the compensation, the better the work discipline. The company needs to improve the existing leadership and the compensation given to employees so that employee work discipline increases.
PENGARUH LIKUIDITAS, LEVERAGE, PROFITABILITAS TERHADAP HARGA SAHAM PROPERTY REAL ESTATE DI BEI
Authors: Ratnawati Dewi , Suwaidi Rahman Amrullah
Published: July 2022

This study aims to identify the effect of liquidity ratios, leverage, and profitability on stock prices of property and real estate companies listed on the Indonesia Stock Exchange. The results of the F test obtained the value of Sig. F- Calculate 0.002 < 0.05, which means that the variables Current Ratio (CR) (X1), Debt to Equity Ratio (DER) (X2), and Return On Assets (ROA) (X3) simultaneously affect stock prices. ( Y) Property and Real Estate company listed on the Indonesia Stock Exchange. On the other hand, the t test results show Sig. t-count, Current Ratio (CR) = 0.776> 0.05, Debt to Equity Ratio (DER) = 0.047 <0.05, and Return On Equity (ROE) = 0.003 < 0.05. From the partial calculation, the variable Debt to Equity Ratio (DER)(X2) and Return On Assets (ROA)(X3) have a significant influence on the Stock Price (Y) of the Property and Real Estate Industries listed on the Indonesia Stock Exchange. The Variable Current Ratio (CR) (X1) does not significantly affect the Stock Price (Y) of the Property and Real Estate Industries listed on the Indonesia Stock Exchange.
Analisis Profitabilitas Dan Pertumbuhan Perusahaan Dengan Kebijakan Deviden Sebagai Variabel Moderasi Terhadap Nilai Perusahaan
Authors: Pristi Anissa Hafidza , Anwar Muhadjir
Published: July 2022

This study aims to determine the effect of profitability and company growth with dividend policy as a moderating variable on the value of manufacturing companies in the food and beverage sector listed on the Indonesian stock exchange for 2017 – 2020 period. The research method used is causal research, the sample used is 18 companies, and analyzed with moderated regression analysis. The results of this study, are Profitability has a significant positive effect on Food and Beverage Company Value, Company Growth has no significant effect on Food and Beverage Company Value, Dividend Policy can weaken the influence of Profitability on Company Value, and Dividend Policy does not have a significant effect on Company Growth on The value of the company.
Pengaruh Job Insecurity dan Job Stress terhadap Turnover Intention
Authors: Al Ghiffari Ahmad Zidan , Safitri Rini
Published: July 2022

This study aims to determine the effect of job insecurity and job stress on turnover intention at the Alfi Putra Cigarette Company. This research is included in the quantitative research. The location of this research is the Alfi Putra Cigarette Company which is located in RT.12, RW.04, Kayujaran Hamlet, Gumbleb Village, Pogalan District, Trenggalek Regency, East Java. The number of samples in this study using 100 respondents. The sample in this study were PR employees. Alfi Putra. The variables in this study consisted of independent variables, namely job insecurity and job stress, while the dependent variable in this study was turnover intention. In this study, there are three hypotheses that were processed using the SmartPLS Version 3. Analysis tool. Based on the research results obtained, it can be concluded that (1) Job Insecurity has a significant positive effect on Turnover Intention, (2) Job Stress has a significant positive effect on Turnover Intention, (3 ) Job Insecurity and Job Stress have a significant positive effect on Turnover Intention.
Pengaruh Seleksi dan Penempatan Terhadap Kinerja Karyawan PT. Sukses Mitra Sejahtera Kab. Kediri
Authors: Santovi Mutya Khanza
Published: July 2022

This research aims to determine the effect of selection and placement on employee performance at Sukses Mitra Sejahtera, PT in Kediri district. The population in this research amounted to 704 people, the sampling technique used the Simple Random Sampling and obtained a sample of 88 people. This research uses descriptive statistical analysis method with hypothesis testing using SPSS version 22 software program. Based on the results of the F test, it is proven that the variable selection and placement simultaneously affect employee performance, indicated by a significant value of 0.000 <0.05. The t-test shows that the selection variable has a partial effect on employee performance. This is indicated by the significant value for the selection variable 0.008 <0.05 and for the placement variable it has a partial effect on employee performance. This is evidenced by a significance level of 0.000 < 0.05. The coefficient of determination test shows that the value (R Square) is 0.428. It means that the effect of selection and placement variables on employee performance is 42.8%.

Keywords: Selection, Placement, Employee Perfomance
Pengaruh Pelaksanaan Program Kesehatan Dan Keselamatan Kerja (K3) Terhadap Kinerja Karyawan Pada PT. Kalisuruh Karsa Mandiri Ngawi
Authors: Pradipta Rosi Dicky , Almanshur Fauzan
Published: July 2022

Performance improvement is the result of well-planned employee activities and coordination to carry out all forms of procedures and a good company is a company that truly maintains the safety and health of its employees by making rules on occupational health and safety that are enforced by all employees and company leaders. A healthy workforce is expected to work productively, increase employee productivity, improve employee performance, and support the company's business success in building and developing its business. This research uses descriptive quantitative method. The object of research at PT. Call for Independent Karsa. The sample used as many as 82 respondents with a sampling technique that is simple random sampling. The data of this research are primary data of questionnaires related to occupational health, work safety, and employee performance. Analysis of the data used in this study is multiple linear regression using SPSS software version 25. The results showed that occupational health had a positive and partially significant effect on employee performance. Work safety has a positive and significant effect partially on employee performance. Occupational health and safety have a positive and significant effect simultaneously on employee performance.

Keyword:  Health, safety, employee performance
Progress in Immune Research of Mycoplasma Pneumoniae Infection
Authors: Li Xinyu , Liu Xiaobin
Published: July 2022

Mycoplasma pneumoniae is one of the common pathogens that induce respiratory tract infection with diverse manifestations after infection. In addition to involving nasopharynx, lungs and bronchus, it can also cause a variety of complications, such as myocarditis, nephritis, meningitis, immune hemolytic anemia, etc. Since the continuous development of clinical testing technology, research on Mycoplasma pneumoniae has been gaining momentum, especially the immune mechanism. Therefore, this paper mainly discusses the immune research of mycoplasma pneumoniae infection.