bluuebunny/crossref_metadata_2025 huggingface dataset:
Simulation of ICESat-2 DEM using Machine Learning Algorithms
Authors: Pancholi Shruti , Abhinav A , Bhardwaj Ashutosh
Published: January 2023

Digital Elevation Model (DEM) is a representation of elevation data that represent terrain with or without overlaying objects of the Earth. It is the ideal and most widely used method for determining topography. DEMs are generated from various techniques such as traditional Surveying, Photogrammetry, InSAR, LiDAR, Clinometry and radargrammetry. It has been observed that mostly LiDAR-generated DEMs provide the best accuracy. The unavailability of LiDAR data in most of the region restricts global researchers from high-resolution and accurate DEMs. The recent launch of ICESat-2 with a 13m beam footprint and 0.7m pulse interval, promises elevations at high orbital precision. Its accuracy is of the order of few centimeters in complex topography, because of this ICESat-2 proves to be a good source to generate high-accuracy DEMs. ICESat-2 provides discrete photon data with elevations of points on the Earth’s surface. Traditional interpolation techniques tend to over-smooth the estimated space and still are unable to justify the complicated continuity in the topographical data. Machine learning algorithms are widely being used to extract patterns and spatial extent in geographic data. To estimate a DEM from ICESat-2 LiDAR point data, machine learning regression algorithms are implemented in this study. The present study has been performed for a plain region of Ghaziabad, Uttar Pradesh, India. Studies have shown that Cartosat-1 DEM V3 R1 product provides an accuracy of the order of 2m in predominantly plain regions, hence taken for this region. Current work focuses on comparing various regression-based machine-learning techniques to interpolate DEM from ICESat-2 data The RMSE of the interpolated DEM resulted from the Gradient Boosting Regressor, Random Forest Regressor, Decision Tree Regressor, and Multi-Layer Perceptron Regressor was 7.13m, 7.01m, 7.15m, and 3.76m, respectively when evaluated against the TANDEM-X DEM of the same region. The MLP Regressor is found to perform the best among the four algorithms tested.
Approximation of the Mittag-Leffler functions by Elementary Functions with Physics Applications
Authors: Salas Alvaro
Published: January 2023

In this paper we give approximations to the Mittag-Leffler functions in terms of elementary functions using different methods. This allowed us to establish a practical method we called integerization principle. This principle states that many fractional nonlinear oscillators may be solved by means of the solution to some integer-order Duffing oscillator equation. The accuracy of the obtained results is illsutrated in concrete examples. Formulas for estimating the errors in the approximations are also provided.
Rapid Advancements in Diagnostic Technology during the COVID Pandemic: Important and Difficult Tasks for Medical Laboratories
Authors: Khadka Ram Bahadur , Karki Khimdhoj , Pandey Jitendra , Chaudhary Gautam Prasad , Gupta Santosh Kumar , Dhakal Ganesh , Pant Dhakaraj
Published: January 2023

The disease COVID-19 is brought on by the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) First appeared in China in December 2019 and quickly spread around the world after being declared a worldwide pandemic by the World Health Organization in March 2020. COVID-19, Medical Laboratory Professionals, SARS-COV-2, Diagnostic, Importance and difficulties for testing were the selected terms to search the databases of PubMed and Google Scholar for previously published material. Many diagnostic tests are applied in corona virus detection like Droplet Digital PCR (ddPCR), Multiplex PCR, Loop-mediated Isothermal Amplification (LAMP) and more. There is a lack of availability of molecular and serologic tests that have been clinically validated or authorized by national or international regulatory bodies. Clinical laboratory experts are tackling threats to our global defense and wellness, including infectious diseases. The opportunity to express gratitude to the unsung medical laboratory heroes and COVID0-19 pandemic allies is now greater than ever. Each year, Medical Laboratory Professionals Week should honors those who contribute key diagnostic data that help save lives. This review article explore overall summary on testing methods including Important and Difficult Tasks for Medical Laboratories which will provide good message for better public health matter.
Integrating Synthetic Aperture Radar (SAR) Sentinel 1A and CROPGRO Peanut Simulation Model for Spatial Yield Gap Analysis
Authors: Subramanian Thirumeninathan , Sellaperumal Pazhanivelan , N.S. Sudarmanian , K.P. Ragunath , Ramalingam Kumaraperumal , G. Srinivasan , R Mohan
Published: January 2023

Crop yield data is critical for managing sustainable agriculture and assessing national food security. Current study aims to increase Peanut productivity from current levels by analyzing the yield gap of production potential between theoretical yield and actual farmers’ yields. The spatial yield gap of Peanut for Thiruvannamalai district of Tamil Nadu is examined in this paper by integrating the products of microwave remote sensing (SAR Sentinel-1A) with DSSAT CROPGRO peanut simulation model. CROPGRO Peanut model was calibrated and validated by conducting field experiment at Oilseeds Research Station, Tindivanam during Rabi 2019 for predominant cultivars viz. TMV 7, TMV 13, VRI 2 and G 7. Actual attainable yield was recorded by organizing CCE with help of Department of Agriculture Economics and Statistics in the respective monitoring Villages. Regression analysis between maximum recorded DSSAT Leaf Area Index (LAI) at peak flowering stage of peanut and yield recorded by Crop Cutting Experiment (CCE) for spatial yield estimation of Peanut in Thiruvannamalai district of Tamil Nadu during Rabi 2021 was carried out using ArcGIS 10.6 software. The results showed that the simulated potential yield ranged from 3194 to 4843 kg/ha, whereas actual yield ranged from 1228 to 3106 kg/ha, with a considerable disparity between the actual and potential yield levels (1217 to 2346 kg/ha) of the monitored locations. The minimum, maximum and average yield gaps in Peanut for Thiruvannamalai district was assessed as 1890, 2324 and 2134 kg/ha, respectively. To reduce the production difference (Yield gap) of Peanut cultivation, farmers should focus more on management issues such as time of sowing, irrigation or water management, quantity and sources of nutrients, cultivar selection and availability of quality seeds tailored to each region.
New ICT-based Ratiometric Two-Photon Near Infrared Probe for Imaging Tyrosinase in Living Cells, Tissues and Whole Organisms
Authors: Valverde-Pozo Javier , Paredes Jose Manuel , García-Rubiño Maria Eugenia , Widmann Thomas Johann , Griñan-Lison Carmen , Lobon-Moles Silvia , Marchal Juan Antonio , Alvarez-Pez Jose Maria , Talavera Eva Maria
Published: January 2023

Melanoma is a type of highly malignant and metastatic skin cancer. In situ molecular imaging of endogenous levels of the melanoma biomarker tyrosinase (TYR) may decrease the likelihood of mortality. In this study we proposed the weakly fluorescent probe 1-(4-(2-(4-(dicyanomethylene)-4H-chromen-2-yl)vinyl)phenyl)-3-(4-hydroxybenzyl)urea (DCM-HBU), which releases a strong red-shifted fluorescent signal after a TYR-mediated oxidation followed by hydrolysis of the urea linkage. The large Stokes shift of the dye is owed to the recovery of the intramolecular charge transfer (ICT) effect. The resulting probe derivate shows a highly ratiometric fluorescence output. Furthermore, the simultaneous excitation by two near-infrared (NIR) photons of the released DCM-NH2 fluorophore could avoid the usual drawbacks, such as cellular absorption, autofluorescence and light scattering, due to an usually short wavelength of the excitation light on biological systems, resulting in images with deeper tissue penetration. In addition, the probe is useful for the quantitative sensing of TYR activity in vivo, as demonstrated in zebrafish larvae. This new ratiometric two photon NIR fluorescent probe is expected to be useful for the accurate detection of TYR in complex biosystems at greater depths than other one-photon excited fluorescent probes.
Compulsive Tidying as an OCD Dimension: Clinical and Empirical Evidence
Authors: Prudon Peter
Published: January 2023

The dominant view of cleaning compulsion as a dimension of OCD is that it is motivated by contamination anxiety. However, in daily life, much cleaning is undertaken as part of tidying one’s home. Such cleaning as well as the other tidying chores may equally assume obsessive-compulsive proportions. However, empirical interest in this phenomenon has remained sparse so far. This article aims to increase awareness of this ill-acknowledged symptom cluster among OCD researchers and to invite them to investigate it. After the introduction, clinical evidence for this OCD dimension is dealt with. Next, empirical studies with OCD inventories, which contain items referring to compulsive tidying, are discussed. Two of these made use of an OCD-inventory, devised by the present author. These also provide the data for the main investigation to be discussed in this paper. In that latter study, six OCD-item clusters, among which tidying compulsion, are predicted. These predictions are tested by evaluating and comparing the item-cluster correlations of all six clusters. These also offer a basis to optimize the clusters toward more homogeneous and distinct ones. By comparing predicted with final clusters, the items can be qualified as either hits, false positives, or false negatives. This output provides the details for revising the predictions, but also allows for calculating the values of two global “goodness-of-fit” measures for each predicted cluster. Though the results do not completely endorse the predicted composition of part of the clusters in the second sample, tidying compulsion is doing rather well. To determine the incidence of tidying compulsion based on the cluster scores, decisions had to be made about what constitute a cluster score, how its gravity can be estimated, and what should be the cut-off per cluster to divide the sample into clinical and subclinical cases on each cluster. If these ‒ unavoidably arbitrary ‒ decisions are accepted, both samples show an incidence of tidying compulsion of around 25%. After a brief critical evaluation of all discussed studies, it is concluded that the evidence presented, though modest, is solid enough to warrants further research into tidying compulsion.
Pan-cancer evaluation of clinical value of mitotic network activity index (MNAI) and its predictive value of immunotherapy
Authors: Mao Xuanyu , Cai Yimeng , Long Sarah , Perez-Losada Jesus , Mao Jian-Hua , Chang Hang
Published: January 2023

Increased mitotic activity is associated with the genesis and aggressiveness of many cancers. To assess the clinical value of mitotic activity as prognostic biomarker, we performed a pan-cancer study on the mitotic network activity index (MNAI) constructed based on 54-gene mitotic apparatus network. Our pan-cancer assessment on TCGA (33 tumor types, 10,061 patients) and validation on other publicly available cohorts (23 tumor types, 9,209 patients) confirmed the significant association of MNAI with overall survival, progression-free survival and other prognostic endpoints in multiple cancer types, including Lower-Grade Gliomas (LGG), Breast Invasive Carcinoma (BRCA) and many others. We also showed significant association of MNAI with genetic instability, which provides a biological explanation of its prognostic impact at pan-cancer landscape. Futhermore, we found that patients with high MNAI benefit more from anti-PD-1 and Anti-CTLA-4 treatment. In addition, we demonstrated on LGG and BRCA that the multimodal integration of MNAI and the AI-empowerd Cellular Morphometric Subtypes (CMS) significantly improved the predictive power of prognosis compared to MNAI and CMS alone. Our results suggest that MNAI can be used as a potential prognostic biomarker for different tumor types toward different clinical endpoints, and multimodal integration of MNAI and CMS exceeds individual biomarker for precision prognosis.
Food Intolerance and Sensitivity are Associated with Chronic Musculoskeletal Pain in A Self-Selected Community Population
Authors: Thomson Ella , Beer Harriet , Ryan Laura , Philcox Edward , Kelly Clive Anthony
Published: January 2023

Introduction People are presenting with chronic musculoskeletal pain at a younger age, and many fulfil criteria for fibromyalgia. We have recently shown a strong association between fibromyalgia symptoms and autistic traits in a self-selected community population, with the relationship mediated in part by the presence of hypermobility. Many respondents also described food sensitivities and intolerances. This study explores relationships between food issues and fibromyalgia symptoms in this population Methods The study used a nonexperimental, correlational design with data collected from a volunteer sample of 442 adults (aged 18-60) who completed online self-report questionnaires assessing each of fibromyalgia symptoms (ACR criteria), autistic traits (RAADS score) and hypermobility (Beighton’s test). Subjects were also asked to record any food sensitivities, allergies, or intolerances, along with their consequences. Correlation analyses and linear regressions were used to test the relationships between these features and each of fibromyalgia, autistic traits and hypermobility. Data was analysed using parametric and non-parametric techniques to assess the strength and significance of relationships, causes of variance and the potential mediating effect of food-related symptoms in the correlation between fibromyalgia features and autistic traits Results Our self-selected community population had a mean age of 24 years and was 77% female. The prevalence of fibromyalgia, autistic traits and hypermobility was 40%, 65% and 44% respectively. Half of all subjects reported food sensitivity and 31% reported food intolerance. The incidence of food-related symptoms was higher among subjects who met criteria for fibromyalgia than those who reported autistic traits or hypermobility. Food sensitivity and food intolerance were both more significantly associated with fibromyalgia (r=0.24, p>0.001 and r=0.38, p>0.001) than with autistic traits (r=0.15, p>0.01 and r=0.17, p>0.01). Discussion This is the first community study to provide evidence for a direct association between features of fibromyalgia and reported food intolerance and sensitivity. Although self-selected, the findings in our predominantly young population suggest that gluten and lactose consumption may be associated with higher levels of musculoskeletal pain. Avoidance of these foodstuffs was commonly reported to reduce symptoms. Dietary adjustment may merit further investigation as a therapeutic modality for some patients with fibromyalgia.
Screening of palatopharyngeal incoordination in mechanically ventilated critically ill infants
Authors:   Ain Shams University, Egypt, Youssef H.M.I. , Rezk A.R. ,   Ain Shams University, Egypt, Mohamed A.M.A.H. ,   Ain Shams University, Egypt, Salem A.M.R. ,   Ain Shams University, Egypt, Mohamed A.E.A. ,   Ain Shams University, Egypt
Published: January 2023

Objective. Screening of palatopharyngeal incoordination in infants who required mechanical ventilation. Patients and methods. This study included 51 patients admitted to the pediatric intensive care unit (PICU), Faculty of Medicine, Ain Shams University. The study was conducted during the period from February 2021 to February 2022. All patients were divided into five groups according to the results of the Fiberoptic Flexible Endoscopic Evaluation of Swallowing (FEES) postintubation, FEES post-extubation, Videofluoroscopic Swallow Study (VFSS) post-extubation, and dye study: group 1 – not affected infants, group 2 – infants with palatopharyngeal incoordination, group 3 – infants with palatopharyngeal incoordination and gastroesophageal reflux, group 4 – infants with reflux, group 5 – infants with congenital upper air way anomalies. Results. Palatopharyngeal incoordination was detected in 16 (31.3%) patients, congenital upper airway anomalies – in 12 (23.5%) patients, and gastroesophageal reflux – in 10 (19.6%) patients. After three months, palatopharyngeal incoordination was resolved in 92.3% of patients, and 7.7 % had silent aspiration. Conclusion. Palatopharyngeal incoordination is a multifactorial process with the important implications for early diagnosis and interventions to treat this condition in pediatric patients. Key words: silent aspiration, mechanical ventilation, infants, palatopharyngeal incoordination
New approach to treat acute viral infections in children under 3 years of age: multicenter, double-blind, randomized, placebo-controlled trial of imidazolyl ethanamide pentandioic acid
Authors:   Russian Medical Academy of Continuing Professional Education, Moscow, Russian Federation, Zakharova I.N. , Sugyan N.G. ,   Khimki Regional Hospital, Moscow region, Russian Federation, Perminova O.A. ,   City Children’s Clinical Polyclinic No 5, Perm, Russian Federation, Globenko A.А. ,   JSC Valenta Pharm Pharmaceutical Company, Moscow, Russian Federation, Kapashin A.V. ,   JSC Valenta Pharm Pharmaceutical Company, Moscow, Russian Federation, Bagaeva M.I. ,   JSC Valenta Pharm Pharmaceutical Company, Moscow, Russian Federation
Published: January 2023

Acute respiratory viral infections (ARVIs), including influenza, are the most common human infections. Young children are particularly vulnerable to ARVIs due to the specificity of their immune system. Therefore, the search for new effective and safe drugs for children is one of the most important problems in pediatrics. Objective. To assess the efficacy and safety of Ingavirin® syrup 30 mg/5 mL for the treatment of ARVI in children aged 6 months to 3 years. Patients and methods. This study included 240 children aged 6 months to 2 years 11 months and 14 days who had the symptoms of ARVI/influenza upon enrollment. Children were randomly assigned to one of the two groups to receive Ingavirin® or placebo. The drug was taken orally once a day in accordance with the weight/dose table for 5 days. The maximum duration of follow-up was 14 days. Results. We found that Ingavirin® ensured more rapid symptom resolution and pathogen elimination than placebo. Key words: influenza, imidazolyl ethanamide pentandioic acid, Ingavirin®, acute respiratory viral infections, antiviral therapy
Granulocyte-macrophage colony-stimulating factor: prospects for use in children with infectious mononucleosis
Authors:   V.F.Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russian Federation, Ikkes L.A. , Savchenko A.A. ,   Krasnoyarsk Research Center of the Siberian Branch of the Russian Academy of Sciences, Research Institute of Medical Problems of the North, Krasnoyarsk, Russian Federation, Martinova G.P. ,   V.F.Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russian Federation, Gvozdev I.I. ,   Krasnoyarsk Research Center of the Siberian Branch of the Russian Academy of Sciences, Research Institute of Medical Problems of the North, Krasnoyarsk, Russian Federation
Published: January 2023

Objective. To analyze the production of active oxygen species (AOS) by peripheral blood neutrophils in children with infectious mononucleosis (IM) after their exposure to granulocyte-macrophage colony-stimulating factor (GM-CSF) in vitro. Patients and methods. We examined 78 children aged 3 to 11 years in the acute period of IM (including 47 children aged 3–6 years and 31 children aged 7–11 years). The control group comprised 40 healthy children matched for age. Luminoldependent chemiluminescence (CL) of peripheral blood neutrophils was assessed using the method of De Sole et al. The following CL parameters were measured: time to reach the maximum (Tmax), maximum value (Imax), and the area (S) under the chemiluminescent curve. Results. Children with IM (from both age groups) demonstrated lower spontaneous lucigenin-dependent chemiluminescence of neutrophils than controls: Tmax (p < 0.001 and p = 0.036, respectively), Imax (p = 0.024 and p = 0.025), and S (p = 0.01). Incubation of neutrophils with GM-CSF caused changes in luminol-dependent chemiluminescence only in children with MI from both age groups: Tmax decreased, whereas Imax and S increased. IM patients aged 7–11 years were found to have higher levels of chemiluminescence of neutrophils exposed to GM-CSF in vitro than IM patients aged 3–6 years (Tmax (p < 0.001) and SGM-CSF/Ssp. (p = 0.024)). Conclusion. Our findings suggest that GM-CSF can increase functional activity of neutrophils. This might facilitate adaptive immunity at periphery. Key words: infectious mononucleosis, neutrophilic granulocytes, chemiluminescence of neutrophils, granulocyte-macrophage colony stimulating factor
Cardiovascular risks in obese adolescents
Authors:   Multidisciplinary Clinic «Scandinavia», Saint Petersburg, Russian Federation, Milner E.B. , Evdokimova N.V. ,   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russian Federation, Novikova V.P. ,   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russian Federation, Khavkin A.I. ,   Academician Yu.E.Veltischev Research and Clinical Institute for Pediatrics, Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: January 2023

The problem of overweight in young people is highly relevant now, because the prevalence of obesity-related complications, including cardiovascular risks, is rapidly increasing. The most common complication of overweight is metabolic syndrome, when obesity is often associated with essential hypertension (EH), dyslipidemia and insulin resistance. Objective. To analyze the risks of cardiovascular disorders in obese adolescents. This is a literature review, where we used theoretical methods, such as analysis, classification, systematization, and generalization of data. In all age groups, the first clinical complication of obesity is EH, the degree and course of which significantly affect the obesity prognosis and determine the probability of early cardiovascular complications. Up to 80% of obese children and adolescents are found to have high blood pressure (BP). Each extra kilogram increases systolic BP by 0.36 mmHg and diastolic BP by 0.1 mmHg. The prevalence of EH increases with increasing body weight. Obese people are 2 to 3 times more likely to develop coronary heart caused by atherosclerotic lesions in the coronary arteries with subsequent fatal cardiovascular events. Higher incidence of cardiovascular diseases in obese patients is presumably associated with endothelial dysfunction and subclinical inflammation. Cardiovascular disorders became more prevalent in young people over the last decade. They are often diagnosed in adolescence. Conclusion. Despite the significance of this healthcare problem, no universal clinical and metabolic markers of cardiovascular damage have been identified so far. The structural and geometric rearrangement of the myocardium in obese patients have not been sufficiently studied. Key words: cardiovascular risks, cardiovascular pathology, obesity, metabolic syndrome, adolescence, puberty, essential hypertension
Comparances in Quality of Chocolate Mousse Using Chocolate Compound with Chocolate Couverture
Authors: Fika Yulianti Fasha  , Rusilanti  , Guspri Devi Artanti
Published: January 2023

Abstract

The purpose of this study is to analyze and compare the sensory quality of chocolate mousses made from two kinds of chocolate, namely compound and couverture. This study was conducted in the Pastry Laboratory, Culinary Arts Study Program, Faculty of Engineering, Universitas Negeri Jakarta from December 2019 to January 2022. This study used the experimental research method. U Mann Whitney test results show that there are significant differences in the sensory quality aspects with a significance level of α = 0.05.The analysis results show that the higher average scores between the two kinds of chocolate are as follows: in the color aspect was 3.4 for couverture chocolate (dark brown category), in the aroma aspect was 4.2 for couverture chocolate (somewhat strong chocolate aroma category), in the taste (sweetness) aspect was 4.5 for compound (sweet category), in the taste (chocolate flavor) aspect was 4.76 for couverture chocolate (rich chocolate flavor category), and in the texture aspect was 4.5 for compound chocolate (soft texture category). It is concluded that there are significant differences in color, aroma, taste (sweetness), and taste (chocolate flavor) aspects of sensory quality and no significant difference in the texture aspect.

Keyword : Chocolate Mousse, Compound Chocolate, Couverture Chocolate, Sensory Quality
Implementation of Problem-Based Learning Model in Improving Speaking Skills for Part-Time Students at A Higher Education Institution in Semarang
Authors: Hamsia Waode , Erydani Vinsensia Anisa Citta
Published: January 2023

The ability to communicate verbally is considered to be one of the important factors for basic language skills. This competency plays a significant role in oral communication. The purpose of this study was to determine whether or not the use of a model called Problem-Based Learning (PBL) might help students enhance their speaking ability. PBL is one of the learning models that can be used in language classes because the focus of the learning model is involving students in the learning process. The PBL model encourages meaningful interactions for the working students who study in part-time class as the special program. Since the students must be trained to practice speaking English. Therefore, speaking competence can be achieved through the activities. Observation and a questionnaire were the two techniques that were used to collect the data. The results showed that the PBL model used by the lecturer in the teaching and learning process that focuses on the discussion to get the alternative solution deeply can make students understand every detail in practicing speaking with real-life issues that require real-life solutions. Thus, this study implied that PBL as a learning model for English subjects was appropriate to make students fluent to communicate in English
The Analysis of Students’ Difficulties in Understanding Learning Concepts on Using Zoom Cloud Meeting in Virtual Classrooms
Authors: Agustin Rury Ayu , Lina Marisa Fran
Published: January 2023

Today many people are interested in implementing the concept of virtual classes, such as using Zoom Cloud Meetings for learning. Therefore, the authors are interested in discussing the difficulties of students in understanding learning activities using Zoom Cloud Meeting in virtual classes. The purposes include describing the kind of learning activities using Zoom Cloud Meeting in virtual classes and determining the students’ difficulties using Zoom Cloud Meeting in virtual classes. This study uses qualitative methods. The data collection techniques are interviewing ten respondents from the fifth-semester English Education Department of an Islamic University in Central Java, and the documentation. The results of this study indicate that learning by using zoom helps students and teachers meet virtually face-to-face. Zoom has various features that support the learning process, such as screen sharing, raising hand icons, chat comments, screen recording, and many other potential features. However, many students say that although Zoom has complete features, this application also has several shortcomings that become obstacles for students in understanding the concept of learning. These include limited-time usage and lag applications if the network or quota is insufficient. This study implied that Zoom Cloud Meeting makes the learning material not conveyed well; thus, the students' understanding becomes incomplete or partial.
Massive Multiplayer Online Role-Playing Games to Enrich Vocabulary to Foreign Language Learners: The Implementation
Authors: Miftahuddin Damar , Malihah Noor
Published: January 2023

Massive Multiplayer Online Role-Playing Games (MMORPGs) are increasingly used to improve language learning. Many games have been created as products to help players improve their learning abilities. This research explores the execution of the MMORPGs to improve their vocabulary. The information was gathered through observation, documentation, and interview. There are seven chosen experienced players of MMORPG in worldwide servers who meet the requirements. Results demonstrated that implementing MMORPG can assist the EFL learners with acquiring new vocabulary from the aspect of the game like socializing, guild, mission, storyline, trading market, and things depiction assist the EFL learners with learning new vocabulary. The results of the study were expected to help the EFL learner gamer learn English, especially vocabulary, since the game has many aspects that help the EFL learners who play this game to enrich their vocabulary.
Mathematical models for calculating the economic efficiency of the implementation of the results project activities in the work of medical organizations and health authorities
Authors:   Main Military Medical Directorate of the Ministry of Defense of the Russian Federation, Trishkin D. V. , Gurov A. N. ,   Federal State Budgetary Institution "State Research Testing Institute of Military Medicine "of the Ministry of Defense of the Russian Federation
Published: January 2023

The article provides specific mathematical models for calculating economic efficiency implementation of the results of project activities in the work of medical organizations and management bodies healthcare. The overall economic effect is determined on the basis of an innovative result with a financial effect, prevented economic damage, medical effect and economic effect from cost savings, based on an assessment of the quality of life related to health, social, managerial, medical and environmental, educational, advertising and scientific and technical effects. After correlating the effect with costs, the economic efficiency of the implementation of the results of project activities is calculated into the practice of health care.
Lessons from the COVID‑19 pandemic
Authors:   Expert on the issues of regulatory and legal regulation of health care activities, Piven D. V.
Published: January 2023

The article presents a list and justification of a number of the most important lessons of the coronavirus pandemic that are directly related to public health issues. The author notes that in the course of the fight against the pandemic, many problematic factors and issues have arisen, the impact of which on the health of the population should be analyzed and evaluated as quickly as possible. The analysis of the lessons of the COVID‑19 pandemic is extremely important for improving the effectiveness of measures to prevent the pandemic, maximizing the consideration and reduction of the risks of possible negative consequences in decision-making, and ensuring appropriate preparedness in the near future.
Role of nurse in geriatrics – status of the question
Authors:   North-Western State Medical University named after I. I. Mechnikov, Lapteva E. S. , Aristidova S. N. ,   North-Western State Medical University named after I. I. Mechnikov, Ariev A. L. ,   North-Western State Medical University named after I. I. Mechnikov, Tsutsunava M. R. ,   North-Western State Medical University named after I. I. Mechnikov, Arieva G. T. ,   North-Western State Medical University named after I. I. Mechnikov
Published: January 2023

The article provides an overview of the discussion problem – the role of geriatric nurse in geriatric practice. The ageing of the population and, in this regard, the increase in the load and increased requirements for the health sectors led to a revision of the concept of geriatric care for the population. However, so far the role of the nurse in rendering medical and medico-social assistance to patients of the senior age groups is finally not defined.The review included materials published from 2015 to 2020.
FEATURES OF PAYMENT FOR CASES OF DRUG THERAPY FOR ONCOLOGICAL DISEASES IN 2021
Authors:   Federal Research Institute for Health Organization and Informatics of Ministry of Health of the Russian Federation, Obukhova O. V.
Published: January 2023

For the first time, the Program of State Guarantees of free medical care for citizens for 2021 includes lists of cases of specialized medical care provided in day- and round-the-clock hospital conditions, and coefficients of differentiation to the share of wages and other expenses that apply to containers in case of antitumor drug therapy of malignant neoplasms are established
Review of Approaches to Accounting and Analysis of Adverse Events in Medical Activity
Authors:   “National Institute of Quality” Roszdravnadzor, Minulin I. B. , Shvabskiy O. R. ,   “National Institute of Quality” Roszdravnadzor, Ivanov I. V. ,   “National Institute of Quality” Roszdravnadzor, Matytsin N. O. ,   Peoples' Friendship University of Russia, Shcheblykina A. A. ,   “National Institute of Quality” Roszdravnadzor, Taut D. F. ,   “National Institute of Quality” Roszdravnadzor
Published: January 2023

The article presents a review of the literature on the organization and conduct of accounting, analysis and monitoring of undesirable events in the performance of medical activity, which is one of the essential measures of internal quality and safety control of medical activity in medical organizations in accordance with the Order of the Ministry of health of the Russian Federation № 785n of Jule 31, 2020 “On approval of requirements for the organization and conduct of internal quality control and safety of medical activities”.
Neighborhood Proactive Policing and Racial Inequities in Preterm Birth in New Orleans, 2018‒2019
Authors: Jahn Jaquelyn L. , Wallace Maeve , Theall Katherine P. , Hardeman Rachel R.
Published: January 2023

Objectives. To measure neighborhood exposure to proactive policing as a manifestation of structural racism and its association with preterm birth.

Methods. We linked all birth records in New Orleans, Louisiana (n = 9102), with annual census tract rates of proactive police stops using data from the New Orleans Police Department (2018–2019). We fit multilevel Poisson models predicting preterm birth across quintiles of stop rates, controlling for several individual- and tract-level covariates.

Results. Nearly 20% of Black versus 8% of White birthing people lived in neighborhoods with the highest rates of proactive police stops. Fully adjusted models among Black birthing people suggest the prevalence of preterm birth in the neighborhoods with the highest proactive policing rates was 1.41 times that of neighborhoods with the lowest rates (95% confidence interval = 1.04, 1.93), but associations among White birthing people were not statistically significant.

Conclusions. Taken together with previous research, high rates of proactive policing likely contribute to Black‒White inequities in reproductive health.

Public Health Implications. Proactive policing is widely implemented to deter violence, but alternative strategies without police should be considered to prevent potential adverse health consequences. (Am J Public Health. 2023;113(S1):S21–S28. https://doi.org/10.2105/AJPH.2022.307079 )
Police Violence: Reducing the Harms of Policing Through Public Health–Informed Alternative Response Programs
Authors: Spolum Maren M. , Lopez William D. , Watkins Daphne C. , Fleming Paul J.
Published: January 2023

Police violence is a public health issue in need of public health solutions. Reducing police contact through public health–informed alternative response programs separate from law enforcement agencies is one strategy to reduce police perpetration of physical, emotional, and sexual violence. Such programs may improve health outcomes, especially for communities that are disproportionately harmed by the police, such as Black, Latino/a, Native American, and transgender communities; nonbinary residents; people who are drug users, sex workers, or houseless; and people who experience mental health challenges.

The use of alternative response teams is increasing across the United States. This article provides a public health rationale and framework for developing and implementing alternative response programs informed by public health principles of care, equity, and prevention.

We conclude with recommendations for public health researchers and practitioners to guide inquiries into policing as a public health problem and expand the use of public health–informed alternative response programs. (Am J Public Health. 2023;113(S1):S37–S42. https://doi.org/10.2105/AJPH.2022.307107 )
The Communal Dimension of Intellectual Property Rights: An Integrative Legal Perspective on the Future of Geographical Indications
Authors: Rompegading Melantik , Asmah
Published: January 2023

This study aims to analyze the communal dimensions of geographical indication intellectual property rights with an integrative legal perspective. This research is a normative legal research. The results of the study confirm that the character of geographic indication rights which have a communal basis is actually relevant to the legal character of the Indonesian people who view intellectual property as joint property and can be used jointly. Therefore, the character of geographical indication rights that have a communal basis in the future can be regulated through legal instruments regarding Traditional Cultural Expressions which also contain provisions regarding geographic indication rights. This actually requires the role of the state as a trigger for the birth of a conducive economic climate by optimizing intellectual property in the form of geographical indications. Future arrangements for geographic indication rights in an integrative legal perspective can be carried out by optimizing the role of the government (bureaucracy) as a social changer. The role of the bureaucracy is based on laws and policies made by the central government and local governments. It is necessary to provide incentives for communities or legal entities that have an orientation to optimize geographic indications. The existence of incentives from the government should also be optimized in the realm of local government so that people are motivated to optimize geographical indications which can be used as a means to improve the economic level of the community.
Instagram Management Strategy as a Public Information Media by The Government of Bogor City During Covid-19 Pandemic
Authors: Lestari Ade Putri , Rohimakumullah Muhammad Al Assad
Published: January 2023

The Covid-19 pandemic has encouraged the Bogor City Government to adapt to all forms of new habits in its public relations activities, one of which is by using Instagram as a public information medium to disseminate important information to the broader community. The purpose of this research was to determine the Instagram management strategy used by the Bogor City Government during the Covid-19 pandemic. This research uses a case study qualitative approach. The informant determination technique used is purposive sampling. The researcher chose informants who came from the internal Diskominfo Kota Bogor because they were considered according to the required criteria, namely being responsible for managing Instagram for the Bogor City Government. This research also uses data validity techniques, namely triangulation of data sources. The results of this research indicate that the Bogor City Government implements a public relations strategy process, including Fact-finding which is the way managers obtain materials for Instagram content, Planning which is the process of formulating and determining strategies and the objectives of Instagram management, Communication which is the use of creative content as a way of to implement a predetermined Instagram management strategy, and Evaluation which is conducting social media monitoring to evaluate the Bogor City Government Instagram management.
Ojung As A Cultural Tradition of Calling for Rain In Tongas Kulon Village, Probolinggo
Authors: Chumairo Chumairo , Sufyanto Sufyanto
Published: January 2023

This study aims to describe and explain the meaning of communicative messages in the ojung tradition in Tongas Kulon Village, Probolinggo. That the local cultural traditions in Tongas village which are often believed to be a prayer to ask for rain. The ancestral cultural traditions that are still closely believed but cannot be understood in terms of the meaning contained therein. This research method is descriptive qualitative using Symbolic Interactionism approach by George H. Mead, with Snowball Sampling technique was used to determine informants. Data was collected  was by means of semi-structured interviews, observation, and documentation, as well as literature review relevant to cultural traditions. The result of this study indicate that the meaning of communicative messages in the ojung tradition in Tongas Kulon Village, Probolinggo by communicating in the form of symbols on devices that have been interpreted, include: (a) a strong and successful personality, (b) purity of heart in oneself each person, (c) human relationship with Nature and God, (d) beauty and honesty. The communicative message conveyed is also an embodiment of prayer to ask for rain, and mercy and to maintain friendship between residents. The moral message contained is that traditions have ancestral cultural values, with people who respect each other’s ancestral culture in the form of their respective beliefs and beliefs about traditions, as well as prayers and hopes that can be answered. And as a forum for closer friendship between people, so as to create a harmonious life among each other.
Competence of Social Attitudes at Madrasah Ibtidaiyah: A Science Learning Model Based on Social Intelligence from an Islamic Perspective
Authors: Faliyandra Faisal
Published: January 2023

The destruction of natural and human resources is caused by an imbalance between good relations with Allah SWT (vertical) and between humans (horizontally). The Islamic perspective of social intelligence bridges the imbalance of two dimensions that are related well according to Islam (Hablum Minannas and Hablum Minallah). This study aimed to analyze the need for an integrated science learning process with social intelligence from an Islamic perspective. The research approach used is qualitative with a needs analysis. This study involved 8 teachers spread across MI Thoriqun Najah and MI Nurul Huda Kapongan Situbondo. Data was collected through literature study, interviews, and documentation. The results of the study stated that 1) the teacher's desire to integrate science learning and social intelligence with an Islamic perspective, 2) There are ten basic competencies which are derived from the core competencies of social attitudes (KI-2), which can be integrated into science learning based on social intelligence from an Islamic perspective. This depends on the creativity of the teacher in seeking innovative learning, 3) The most effective method used for learning science-based on social intelligence from an Islamic perspective is the group and demonstration model, 4) Relevant scoring systems can be used for assessment in the social intelligence-based science learning process. Islamic perspective, namely non-test with questionnaires, performance appraisal observations, and portfolios.
Development of Minimum Competency Assessment (AKM)-Based Exercise Books to Improve Students' Literacy and Numeracy Skills at Sdn Janti 02 Sidoarjo
Authors: Nuzulia Nuril , Gafur Abd
Published: January 2023

Develop a Minimum Competency Assessment-Based Exercise Book to Improve Students' Literacy and Numerical Ability at SDN Janti 02 Sidoarjo to provide exciting and creative learning media in a lesson that aims to improve student learning outcomes. This is one of the reasons behind this development research. The study aimed to develop a minimum competency assessment-based exercise book to enhance students' literacy and numeracy skills at SDN Janti 02 Sidoarjo. This research and development method uses the research and development (R&D) type of Borg & Gall. The results of the development were in the form of a "Pintar AKM" exercise book for Grade 5 elementary schools. (1) the results of this research and development meet the valid criteria with the acquisition of validity, material experts get 90.6%, design experts get 89.3%, and learning experts get 94.6%. (2) the results of the trial to assess the attractiveness of the exercise book based on the minimum competency assessment developed for students at SDN Janti 02 Sidoarjo was 91.8%. (3) student learning outcomes have increased, as seen from the pre-test results of 70.8 and post-test scores of 90.4, so it can be said that the minimum competency assessment-based exercise book is appropriate for students to use.
Development of Smart Apps Creator-Based Learning Media on Religious Diversity Materials in Indonesia
Authors: Mulyoto Galih Puji , Subagyo Luthfia Aldila Arsy Subagyo , Sutomo
Published: January 2023

This study aims to develop a product that is tested to be valid and interest so that it is can help the student learning process in understanding the material on religious diversity in Indonesia. The research method used is Research and Development (R&D) by applying the ADDIE development model. The results of this study are in the form of learning media products based on smart apps creators that very valid criteria (86%) from material expert validators and media with valid criteria from media expert validators (80%) and media is also categorized as a very interesting (82.7%). Based on the validation results and the results of field trials, it can be concluded that the smart apps creator-based learning media that contains material on religious diversity is very valid and very interesting to be used as a Civics learning medium in class IV MI Perwanida Blitar.
O ritmo no direito, o ritmo na música
Authors: Moustaira Elina
Published: January 2023

Partindo do argumento segundo o qual a interpretação musical está mais próxima do direito do que da interpretação literária – pois ela também compreende a noção de performance –, este texto analisa as noções de ritmo musical e ritmo jurídico. Para esse fim, ele toma como exemplos as manifestações musicais dos gitanos andaluzes e dos esquimós.