bluuebunny/crossref_metadata_2025 huggingface dataset:
Diffusion kurtosis versus diffusion-weighted MRI in differentiating clear cell renal cell carcinoma and renal angiomyolipoma with minimal fat: a comparative study
Authors: Zhu Qingqiang , Feng Xinyu , Sun Jun , Ye Jing , Zhu Wenrong , Chen Wenxin
Published: March 2024

Background
Apparent diffusion coefficient(ADC) assessment has also shown benefit in distinguishing renal tumor types, however, there is always concern that the ADC obtained from conventional monoexponential diffusion-weighted imaging (DWI) could not accurately reflect the real diffusivity, because of the influence of microcirculation. The aim of the current study was to produce a quantitative comparison of the potential of various diffusion parameters obtained from DWI and diffusion kurtosis imaging(DKI) in differentiating clear cell renal cell carcinoma (ccRCC) and renal angiomyolipoma with minimal fat(RAMF).
Methods
Sixty-eight patients with ccRCC and 18 patients with RAMF were retrospectively studied. For DKI and ADC, respiratory triggered echo-planar imaging sequences were acquired in axial plane (three b-values: 0, 1000, 2000s/mm2) and (one b-value: 2000s/mm2). Mean Diffusivity (MD), fractional Anisotropy (FA), mean kurtosis (MK), kurtosis anisotropy (KA), radial kurtosis (RK) and apparent diffusion coefficient (ADC) were performed. The diagnostic efficacy of various diffusion parameters for predicting ccRCC and RAMF was compared.
Results
The ADC and MD values of ccRCCs were higher than those of RAMFs (p < 0.05), while comparable FA, MK and KA values were found between ccRCCs and RAMFs (p > 0.05). Moreover, the RK values of RAMFs were higher than those of ccRCCs (p < 0.05). ROC curve analyses showed that MD values had the highest diagnostic efficacy in differentiating ccRCCs from RAMFs. For pairwise comparisons of ROC curves and diagnostic efficacy, ADC was worse than DKI analysis (p < 0.05).
Conclusion
DKI analysis performs better than ADC analysis in differentiating ccRCC and RAMF.
Artificial Intelligence for Computer Vision: Bibliometric Analysis
Authors: Oke Oluwafemi , Cavus Nadire
Published: March 2024

Computer Vision (CV) is a prominent area of focus in Artificial Intelligence (AI) research, with applications ranging from self-driving cars to medical imaging. A bibliometric analysis is presented in this study for the latest research in AI for CV, focusing on advancements in CV models, their evaluation, and their use in various applications from 1981 to 2023 using Web of Science Clarivate Core Collection database and a dataset of 1857 retrieved publication. VOS viewer and CiteSpace software were implemented to perform science mappings and bibliometric analysis techniques in the study. Hence, analysing citation networks, publication output, and collaboration patterns in the field to identify influential research publications, researchers, and institutions. The analysis reveals the top publications and researchers in the field, as well as the most common research topics and their relative importance. This study finds that deep learning techniques, such as convolutional neural networks (CNNs), are the dominant approach in CV research, with applications in object detection, feature extraction, and image analysis. Also, it found that USA has a wide partnership and collaborative range amongst making it the most productive country. This study also discussed few of the challenges and opportunities in AI for CV, including U-Net not generating more precise segmentation in biomedical image segmentation. The recommendation of this study for future research direction is the need for more interdisciplinary collaboration, the development of new evaluation techniques, and the exploration of novel applications of AI for CV. The bibliometric analysis results will be of interest to researchers, practitioners, and policymakers interested in AI, CV, and related fields, as well as anyone interested in the latest advancements in this exciting and rapidly evolving field.
Peripheral administration of sepiapterin replenishes brain tetrahydrobiopterin: a pharmacodynamic study
Authors: Ohashi Akiko , Nakamaru-Ogiso Eiko , Matsuoka Hiroshi , Aizawa Shin , Hasegawa Hiroyuki
Published: March 2024

Background
The levels of brain tetrahydrobiopterin (BH4), a coenzyme of tryptophan hydroxylase and tyrosine hydroxylase, regulate the rates of monoamine synthesis, including serotonin, dopamine, and noradrenaline. The attempt to treat congenital or acquired central nervous system (CNS) disorders caused by monoamine deficiency with synthetic BH4, 6RBH4, has failed owing to its limited permeation through the blood-brain barrier (BBB). Sepiapterin (SP), a BH4 precursor, is known to be rapidly assimilated into cellular BH4 through the BH4-salvage pathway. However, no treatment attempts with SP have been made, owing to the concerns about its ability to reach the brain parenchyma when administered peripherally. Therefore, we investigated the pharmacodynamics of SP entry into the CNS following intraperitoneal (ip) administration of SP.
Methods
To assess SP delivery, we derived an equation describing brain cell-uptake of SP as a function of its dose based on a tandem barrier model; the BBB and brain cell membranes. We estimated each of the clearances determining the directional component of the flow: influx through the BBB (CLin) and cell uptake (CLuptake) were determined in vitro, while pumping to plasma (CLout) was calculated using in vivo data from previous studies involving direct SP injection into the rat brain ventricle. To validate the model in vivo, we administered various SP doses to mice and measured the resulting increase in brain BH4 levels. To distinguish BH4 increases due to cellular uptake of SP from those due to influx of exogenous BH4, the quantification was performed 6 hours after administration, when BH4 influx had ceased.
Results
The model equation predicted a linear increase in brain BH4 with plasma SP, with a clearance CL(plasma→cells) = 5.42–10.2 µL·min-1·g-1. In vivo results showed that suprathreshold doses (> 13.3 mg/kg, mice, ip) linearly increased brain BH4 concentrations. In this context, SP reached the brain, or was taken up, with an AUCplasma = 1.3–2.45 µM·min per 1 mg/kg-body.
Conclusions
Peripheral administration of SP at a practical dose range increases brain BH4 levels in a dose-dependent manner. SP treatment could be a promising therapy to enhance monoamine synthesis in various monoamine neurotransmitter deficiencies.
Adaptive Drop Approaches to Train Spiking-YOLO Network for Traffic Flow Counting
Authors: Zhang Bin , Wu Liangshun , Liu Peilin , Juan Hu , Luo Meizhen , Peng Ling
Published: March 2024

Traffic flow counting is an object detection problem. YOLO (" You Only Look Once ") is a popular object detection network. Spiking-YOLO converts the YOLO network from ANN(artificial neural network) to SNN (spiking neural network), which consumes less power than YOLO. However, Spiking-YOLO is difficult to train and has poor accuracy because of overfitting. Dropout and DropConnect are two methods to regularize neural network models and have produced cutting-edge outcomes in many benchmarks. The two drop approaches are first applied to Spiking-YOLO. Considering that a higher membrane potential of a biological neuron implies a higher probability of neural activation, we propose three adaptive drop algorithms—Spiking-YOLO with adaptive Dropout, Spiking-YOLO with adaptive DropConnect, and Spiking-YOLO with group adaptive Drop, which adaptively adjusts the keep probability for training SNNs. The experimental results show that the adaptive algorithms have fast convergence speed with high detection accuracy and mAP value, and work well in the case of high-speed streaming video, making them suitable for online learning scenarios.
Refraktives und visuelles Ergebnis nach Neuausrichtung von rotierten torischen Intraokularlinsen
Authors:   , Sartory Tsvetina Georgieva
Published: March 2024

Hintergrund und Ziel der Studie Das Ziel der Studie ist die Beurteilung des refraktiven und visuellen Ergebnisses von Patienten mit fehlausgerichteten torischen IOLs nach operativer Neuausrichtung, mit und ohne Rückberechnung der torischen Achse nach Implantation der IOL. Methoden Dies ist eine retrospektive Analyse von 39 Patienten, die sich von August 2013 bis Dezember 2019 an der Klinik für Augenheilkunde der Goethe-Universität Frankfurt am Main einer zweiten Operation zur Neuausrichtung einer fehlausgerichteten torischen IOL unterzogen haben. Die zweite Operaton zur Korrektur der Achsenlage wurde auf zwei Weisen durchgeführt: In der ersten Gruppe wurde auf die primär berechnete Achse rotiert und in der zweiten Gruppe wurde die Rotation auf eine neu berechnete Achse mit dem Rückrechner von astigmatisfix.com vorgenommen. Ergebnisse In dieser retrospektiven Studie wurden 39 Augen von 39 Patienten eingeschlossen. Die Ergebnisse nach der ersten Operation (die Linsenoperation) zeigte eine Besserung der (BCVA) von 0,28 ± 0,22 logMAR (20/40) auf 0,15 ± 0,14 logMAR (20/32). Nach der Linsenoperation zeigten die torischen IOLs durchschnittlich eine postoperative Fehlstellung von 25,69° ± 26,06°. Verglichen vor und nach der Rotation der torischen IOL blieb der BCVA unverändert bei 0,14 ± 0,14 logMAR (20/32), während sich der UDVA signifikant von 0,39 ± 0,29 logMAR (20/50) auf 0,27 ± 0,18 logMAR (20/40) verbesserte. Das refraktive Ergebnis zeigte eine Reduktion sowohl in der Restsphäre sowie in dem Zylinder. Die Ergebnisse der Gruppenanalyse demonstrierte für die erste Gruppe (Neuausrichtung auf die präoperativ berechnete Achse) eine postoperative UDVA 0,24 ± 0,16 logMAR mit einem Zylinder von 0,90 ± 0,90 D. In der zweiten Gruppe (Ausrichtung auf eine zurückberechnete Achse) betrug die UDVA 0,32 ± 0,20 logMAR mit einem Zylinder von 0,76 ± 0,72 D. Die IOLs mit hoher Zylinderstärke (≥ 2 D) zeigten bei der Rückberechnung eine stärkere Abnahme des Restzylinders als IOL mit niedriger Zylinderstärke (< 2 D) (27 % vs. 9 %). Der mittlere sphärische Äquivalent-Vorhersagefehler der Rückberechnung betrug 0,54 ± 0,55 D. Schlussfolgerung Die Neuausrichtung von fehlausgerichteten torischen IOLs verbessert die Sehschärfe und reduziert verbleibende Brechungsfehler. Insbesondere bei IOL mit hoher Zylinderstärke kann ein besseres refraktives Ergebnis erzielt werden, wenn vor der Neuausrichtung eine Rückberechnung durchgeführt wird.
Influência das Práticas Ambientais, Sociais e de Governança sobre o Desempenho das Empresas Brasileiras
Authors: Correia Forte Hyane , Crisóstomo Vicente Lima , Moura Peixoto Neto Leonardo
Published: March 2024

A preocupação das empresas com as questões Ambientais, Sociais e de Governança (ASG) têm-se tornado relevante para a sociedade. Em função disto, parece que empresas têm passado a dar atenção a estas ações tentando incorporá-las à sua estratégia. Tem sido sugerido que um melhor padrão de ASG da empresa, além de contribuir para aprimorar a gestão, é capaz de gerar sensibilidade favorável dos stakeholders da empresa, e, assim, favorecer seu desempenho. Este trabalho tem como objetivo investigar a influência do engajamento em práticas ASG sobre o desempenho das empresas brasileiras. Para tanto, foi usada uma amostra de 685 observações anuais de 85 empresas listadas na B3 que são avaliadas pelo CSRhub Consensus ESG Ratings. Como proxy para ASG, foi utilizada a avaliação do CSRhub e a presença no ISE. Como proxy para desempenho, adotou-se o desempenho financeiro (ROA e ROE) e o valor de mercado da empresa foi medido pelo Q de Tobin. Estimação de modelos forneceram resultados que indicam haver, no Brasil, uma melhoria de desempenho da empresa que adota mais elevado padrão de ASG. Os resultados são robustos às duas proxies para ASG e às três proxies para desempenho da empresa. Estes achados indicam que, de fato, ASG parece ser capaz de melhorar a gestão da empresa e, em paralelo, de gerar uma sensibilidade positiva de seus stakeholders, o que favorece o ciclo virtuoso entre preocupação da empresa com seus stakeholders e seu desempenho.
ANKYLOSIS OF THE TEMPOROMANDIBULAR JOINT
Authors:   Anesthesia Intensive Care Department, IbnTofail Hospital CHU Mohamed VI, Faculty of Medicine and Pharmacy, Cadi Ayyad University Marrakech., Monteiro A. , Mavoungou P.B. ,   Anesthesia Intensive Care Department, IbnTofail Hospital CHU Mohamed VI, Faculty of Medicine and Pharmacy, Cadi Ayyad University Marrakech., Nde-Ngala M. ,   Anesthesia Intensive Care Department, IbnTofail Hospital CHU Mohamed VI, Faculty of Medicine and Pharmacy, Cadi Ayyad University Marrakech., Ouardi Y.El ,   Anesthesia Intensive Care Department, IbnTofail Hospital CHU Mohamed VI, Faculty of Medicine and Pharmacy, Cadi Ayyad University Marrakech., Khallouki M. ,   Anesthesia Intensive Care Department, IbnTofail Hospital CHU Mohamed VI, Faculty of Medicine and Pharmacy, Cadi Ayyad University Marrakech.
Published: March 2024

Introduction: Difficult intubation is a very dreaded situation in anesthesia and is frequently encountered in maxillofacial surgery15.7%(1)particularlyinpatientswithankylosisofthejoint temporomandibular (TMJ) the scarcity of equipment used in the event of difficult intubation (ID) such as that a nasofibroscopy represents a challenge and requires the use of other techniques (2). The interest of our study is to show the importance of capnography and ultrasound guidance during an ID blind nasotracheal. Comment: It concerns the management of the respiratory tract of a patient aged 41 years and 78 kg followed for epilepsy since childhood, substegretol 200mgx2/jet with congenital TMJ ankylosis. On the basis of preoperative clinical and radiological results, we have found the criteria for ID in particular the impossibility of opening the mouth and with the resources available, an intubation nasotracheal surgery under general anesthesia with spontaneous breathing was considered and a written informed consent for an emergency tracheotomy if required has been obtained from the patient. The procedure successively consisted of pre-oxygenation of the facial mask, xylocaine 0.05% a been sprayed into the right nostril, 0.05% xylocaine gargle, blockage of the laryngeal nerves superior by transcutaneous injections of lidocaine 1% and intra-tracheally, then we performed sedation with propofol 50mg. Blind nasotracheal intubation was successful in one uneventful attempt per No. 6.5 mm reinforced probe, the verification was made by visualizing the intra-tracheal probe at through ultrasound and confirmation by capnography. The anesthesia was completed by the administration of fentanyl 250 gamma, propofol 100 mg and rocuronium 40mg. Maintenance of anesthesia was performed by a mixture of isoflurane (1.5%) and oxygen and air (50%:50%). The patient was extubated after the surgical procedure and the operation was a success. Conclusion: The anesthesia of patients with TMJ ankylosis represents a situation where the difficulties tracheal intubation should be considered in principle, and where an anticipatory strategy should be developed. Due to the absence of anasofibroscopy, the anesthetic treatment must be carried out by a team experienced and trained in blind ID.
KNOWLEDGE OF ANGANWADI WORKERS REGARDING COMPLIMENTARY FEEDING PRACTICES IN A RURAL AREA- A CROSS-SECTIONAL STUDY
Authors:   JR3, Department of Community Medicine, Vilasrao Deshmukh Government Medical College, Latur., Baburao Shinde Madhav , Acharya Namrata ,   Associate Professor, Department of Community Medicine, Vilasrao Deshmukh Government Medical College, Latur., A.S. Nagaonkar ,   Professor and Head, Department of Community Medicine, Vilasrao Deshmukh Government Medical College, Latur.
Published: March 2024

AWWs had good knowledge regarding various CF assessment indicators given by WHO but some technical knowledge need to improve in areas like Dietary Diversity along with continuation of BF up to 2 years. Regular trainings to update knowledge is needed.
Leverage-induced profitability in Bangladeshi firms: An empirical analysis
Authors: Mahima Ima Ummay , Rabeta Maliha , Nahar Nurun , Sharmin Sultana Sumi Mst.
Published: March 2024

The intent of the inquiry is to extensively examine the impact of leveraged financing on firm performance in Bangladesh, revealing the subtle dynamics of leverage-induced profitability and emphasizing the importance of a balanced debt and equity structure for financial sustainability in emerging markets. To explore how financial leverage in an entity’s capital structure affects a business’s financial sustainability and analyze how it may be used to improve company performance, the study has employed a 22-year data set (2000–2021) from the Dhaka Stock Exchange. To perform Fixed Effect Regression based on the Hausman test, ‘Firm performance’ is used as the regressand, which was further proxied by Earnings per Share, Return on Assets, Return on Equity, and Basic Earning Power respectively. Alternatively, proxy variables for the regressor ‘Financial leverage’ include Debt-to-Equity, Debt-to-Asset, Current Liability-to-Equity, and Current Liability-to-Asset. The test has shown that leverage in the capital structure could lead to both favorable and unfavorable effects in emerging countries like Bangladesh. Age, along with Debt-to-Asset, has shown a substantial negative impact on Earnings per Share. Also, the Debt-to-Asset and Current Liability-to-Asset negatively affect the Return on Assets. However, Debt-to-Equity, Current Liability-to-Equity and Size have a substantial positive impact, however Age has a negative effect on Return on Equity. Lastly, Debt-to-Asset has shown a positive impact on Basic Earning Power. The findings suggest that balancing debt and equity is crucial to benefit from leverage-induced profitability, and the models can be extended or amended across industries to expand the study on this persistent leverage-induced profitability argument.
Improving the institution of targeted education: analysis of changes in the law on education
Authors:   St. Petersburg State University, Nogaylieva Fatima K.
Published: March 2024

In the context of the transition to a digital economy, there is a need for qualified specialists with competencies corresponding to these processes. The system of secondary vocational and higher education is the main tool for training personnel for the labor market. The author of the article refers to the mechanism of targeted training as one of the ways to solve problems in the field of personnel training. Ideologically targeted education, in general, has not undergone fundamental changes in the last two decades. It is based on the fact that admission to targeted training at the expense of the state budget is carried out according to separate quotas, and one of the conditions for granting a quota is the conclusion of an agreement with the customer of targeted training - the future employer. However, the details of the targeted receipt procedure and the obligations of the parties to the relationship were not properly regulated in the legislation, which gave rise to rather negative assessments of society towards this basis for the emergence of educational relations. From May 1, 2024, amendments to the legislation on education will come into force, aimed at increasing the efficiency for the economy of targeted education by clarifying the obligations of the parties and their responsibilities, and also designed to make the entire procedure for admission to target places transparent and open on a nationwide scale. The article provides a critical review of the proposed changes in the Law on Education: for the first time given a definition of the concept of targeted education, updated obligations of the parties to the agreement on targeted education, inclusion of the educational organization and the future employer in the number of parties to the agreement, an updated procedure for admission under the agreement on targeted education.
Life cycle assessment of ammonium sulfate recovery from urban wastewater
Authors: Gong Yuxian , Wang Xiaoyuan , Bao Xiaoan , Lam Ka Leung
Published: March 2024

Anthropogenic nitrogen fluxes are profoundly altering the global biogeochemical nitrogen cycle. Better management of these nitrogen fluxes is essential. Recovering nitrogen from urban wastewater reduces both the energy and resources required to produce nitrogen-based fertilizer and to remove nitrogen from wastewater collected. Nitrogen can be recovered from wastewater in the form of ammonium sulfate, a common nitrogen-based fertilizer. In the urban setting, the technology can be applied to target source-separated urine or municipal wastewater. To assess the environmental sustainability of this approach, this study compared the life cycle environmental impacts of ammonium sulfate recovered from urban wastewater (through eight different recovery technology trains) and ammonium sulfate produced by six different industrial processes. The results show that wastewater-derived ammonium sulfate generally has lower potential environmental impacts than industrially produced ammonium sulfate in most of the impact categories assessed. The impact for the source-separated urine centralized recovery train is the smallest. The contribution analysis shows that energy, sulfuric acid and sodium hydroxide use are the major contributors, while the background inventory analysis shows that the results can be sensitive to the choice of region-specific background inventory. In the future, nitrogen recovery from urban wastewater is promising for the circular economy in cities.
Recent advances on the treatment of oilfield-produced water by advanced oxidation processes: A review
Authors: Zhang Huan , Gao Chunyang , Zhang Hongli , Song Naijian , Cao Qiang
Published: March 2024

Despite the advancements in alternative fuels and energy sources, there continues to be a significant global dependence on oil production and extraction. A substantial volume of oilfield-produced water (OPW) is generated during the production and extraction processes of oil fields. Recurrent OPW treatments encountered significant challenges in addressing this particular type of wastewater. Advanced oxidation processes (AOPs) are regarded as a promising alternative approach for the degradation of recalcitrant organic compounds in the OPW. This review focuses on the characterization of OPW. The treatment of organic pollutants in wastewater using AOPs, such as ozonation, Fenton oxidation-based processes, heterogeneous photocatalysis, and persulfate oxidation, is comprehensively reviewed in terms of their efficiency for pollutant degradation. The primary challenges in this field and the future directions for development are proposed, with the aim of providing a valuable reference for achieving highly effective treatment of OPW.
Ultrasound-based Radiomics Predicts Short-term Outcomes in Hepatitis B
Virus-related Acute-on-chronic Liver Failure
Authors: Huang Xingzhi , Yuan Songsong , Xu Pan , Li Yaohui , Zhou Aiyun
Published: March 2024

Background:

The prognosis in hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF) is challenging due to heterogeneity. Radiomics may
enable noninvasive outcome prediction.

Objective:

This study aimed to evaluate ultrasound-based radiomics for predicting outcomes in HBV-ACLF.

Methods:

We enrolled 264 HBV-ACLF patients, dividing them into a training cohort (n=184) and a validation cohort (n=80). From hepatic ultrasound
images, 455 radiomic features were extracted. Radiomics-based phenotypes were identified through unsupervised hierarchical clustering. A
radiomic signature was developed using a Cox-LASSO algorithm to predict 30-day mortality. Furthermore, we integrated the signature with
independent clinical predictors via multivariate Cox regression to construct a combined clinical-radiomic nomogram (CCR-nomogram). Integrated
discrimination improvement (IDI) and net reclassification improvement (NRI) assessed performance improvements achieved by adding radiomic
features to clinical data.

Results:

Both clustering and radiomic signature identified two distinct subgroups with significant differences in clinical characteristics and 30-day
prognosis. In the training cohort, the signature achieved a C-index of 0.746, replicated in validation with a C-index of 0.747. The CCR-nomogram
achieved C-indices of 0.834 and 0.819 for the training and validation cohorts. Incorporating radiomic features significantly improved the CCRnomogram
over the signature and clinical-only models, evidenced by IDI of 0.108-0.264 and NRI of 0.292-0.540 in both cohorts (all p0.05).

Conclusion:

Ultrasound-based radiomics offered prognostic information complementary to clinical data and demonstrated potential to enhance outcome
prediction in HBV-ACLF.
Effect of Liver Segments and Hepatic Fibrosis Grade on Repeatability,
Reliability, and Diagnostic Efficiency of Intravoxel Incoherent Motion
Authors: Huang Lesheng , Chen Jun , Liu Weiyin Vivian , Tian Guangjun , Wei Qian , Peng Hui , Zhang Wanchun , Li Hongyi , Peng Se , Liu Tianzhu
Published: March 2024

Background:

Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) is considered a potential marker of hepatic fibrosis (HF).

Objective:

To explore the influencing factors of repeatability and reliability in IVIM-DWI parameters of ROI-based liver segments in participants with HF
and healthy volunteers (HV) and to assess the diagnostic efficiency of these parameters in HF.

Methods:

Participants with early HF (EHF, n=59) or advanced HF (AHF, n=38) and HV (n=48) were recruited. Two examiners measured IVIM data using
mono-, bi-exponential and stretched exponential models. The results and influencing factors of repeatability and reliability of IVIM-DWI, and the
diagnostic efficiency were analyzed.

Results:

The repeatability of D* (CV: 26.62–41.47%) and DDC (CV: 18.01–34.40%) was poor, the repeatability of ADC (CV: 4.95–9.76%), D (CV:
7.09–15.52%), f (CV: 9.35–17.15%), and α (CV: 7.48–13.81%) was better; ordered logistic regression showed statistically significant results of
IVIM-derived parameters; the reliability showed no obvious trend, and ordered logistic regression showed statistically significant results of IVIMderived
parameters, groups, and partial hepatic segments (all p<0.001). IVIM-derived parameters with relatively good repeatability (CV<20%) and
reliability (ICC>0.4) were used to establish regression models for differential diagnosis. The AUC of regression models was 0.744–0.783 (EHF vs.
AHF), but no statistically significant parameters were found in the HV vs EHF comparison.

Conclusion:

IVIM-derived parameters were the most important factors affecting the repeatability and reliability, while staging of HF and hepatic segments may
be the influencing factors of reliability. IVIM-derived parameters showed medium diagnostic efficiency in distinguishing between EHF and AHF.
Identifying Predictors for Hypoplastic Aortic Arch (HAA) in Pediatric Patients
with Complex Coarctation of the Aorta (CoA)
Authors: Lyu Ying , Tian Lu , Qin Bin , Fan Xiao , He Ling
Published: March 2024

Objective:

HAA is a significant risk factor in complex CoA patients. We conducted a retrospective study to explore the relationship between HAA and other
cardiovascular factors.

Methods:

We analyzed 103 patients diagnosed with complex CoA using CT angiography and echocardiography. Aortic diameter was measured at six levels,
and severe coarctation was defined as coarctation site to diaphragmatic level ratio (CDR) < 50%. Correlations between non-HAA and HAA groups
were assessed. Univariate and multivariate logistic regression identified HAA risk factors.

Results:

Among 103 children with complex CoA, 55 were in the non-HAA group and 48 in the HAA group. The incidence of PDA (56.3% vs. 32.7%, p <
0.05), severe coarctation (CDR < 50%, 81.3% vs. 34.5%, p < 0.01), and collateral arteries (39.6% vs. 0, p < 0.01) were higher in the HAA group
than one in the non-HAA group. The aortic arch size was positively correlated with age and negatively correlated with severe coarctation, VSD,
collateral arteries, and left heart dysfunction. Logistic regression results showed that collateral arteries were risk factors for the whole aortic arch
(proximal arch OR = 11.458; p < 0.01, distal arch OR = 4.211; p < 0.05, and isthmus OR = 11.744; p < 0.01), severe coarctation (OR = 6.653; p <
0.01), and left heart dysfunction (OR = 5.149; p < 0.01) associated with isthmus hypoplasia.

Conclusion:

This study highlights the prevalence of HAA in complex CoA patients and its associations with various cardiovascular factors. These insights
improve diagnosis and treatment approaches.
Face Recognition Using LBPH and CNN
Authors: Shukla Ratnesh Kumar , Tiwari Arvind Kumar , Ranjan Mishra Ashish
Published: March 2024

Objective::

The purpose of this paper was to use Machine Learning (ML) techniques
to extract facial features from images. Accurate face detection and recognition has long been a
problem in computer vision. According to a recent study, Local Binary Pattern (LBP) is a superior
facial descriptor for face recognition. A person's face may make their identity, feelings,
and ideas more obvious. In the modern world, everyone wants to feel secure from unauthorized
authentication. Face detection and recognition help increase security; however, the most difficult
challenge is to accurately recognise faces without creating any false identities.

Methods::

The proposed method uses a Local Binary Pattern Histogram (LBPH) and Convolution
Neural Network (CNN) to preprocess face images with equalized histograms.

Results::

LBPH in the proposed technique is used to extract and join the histogram values into a
single vector. The technique has been found to result in a reduction in training loss and an increase
in validation accuracy of over 96.5%. Prior algorithms have been reported with lower
accuracy when compared to LBPH using CNN.

Conclusion::

This study demonstrates how studying characteristics produces more precise results,
as the number of epochs increases. By comparing facial similarities, the vector has generated
the best result.
PERMAINAN BAHASA SINDIRAN DALAM PROGRAM STUND UP COMEDY BERTAJUK SOMASI PADA PODCAST YOUTUBE DEDDY CORBUZIER (KAJIAN PRAGMATIK)
Authors:   IKIP Budi Utomo, Latifah Iswatul , Kinanti Kingkin Puput ,   IKIP Budi Utomo, Astuti Endang Setiyo ,   IKIP Budi Utomo
Published: March 2024

This research aims to describe: (1) satirical language games in Somasi content on Deddy Corbuzier's YouTube channel, (2) the meaning of language styles in language games in Somasi content on Deddy Corbuzier's YouTube channel. The theories in this research are language games and satirical language styles. This type of research is descriptive qualitative. The data source for this research is Deddy Corbuzier's YouTube channel. The research data is in the form of quotations of words that can be formulated as satirical language games based on the speech in the Somasi content on Deddy Corbuzier's YouTube channel. Based on data analysis and discussion, the research results showed that speakers used 31 pieces of satirical language games. The satirical language games found were abbreviation, reduplication, antonymy, deviation from the maxim of politeness, and deviation from the maxim of cooperation. The dominant language game of satire in the subpoena content on Deddy Corbuzier's YouTube channel is satire. The satirical language game in the Somasi content on Deddy Corbuzier's YouTube channel is a medium for conveying anxiety and criticism, but it is conveyed in a humorous way by comedians as speakers on Deddy Corbuzier's YouTube channel so that the satire and anxiety are conveyed well but do not hurt the feelings of the person being satirized.
Uso de tecnologías CRISPR-CAS9 en microalgas aplicado a la obtención de productos biotecnológicos de interés industrial
Authors: Martinez Tapiero Dalia Yirasol , Martínez Rentería Maria Anghela , Camacho Kurmen Judith Elena
Published: March 2024

Las microalgas se destacan por su capacidad de adaptarse a diferentes medios de cultivo, participación en captura de CO2  y productos de interés biotecnológico cómo biocombustibles, proteínas, biofertilizantes, suplementos alimenticios, pigmentos, entre otros. Se han trabajado diferentes tipos de estrés como variación del pH, deficiencia de nutrientes, estrés salino, cambios en la temperatura y alta irradiancia con el fin de aumentar la producción de metabolitos aplicado a diferentes industrias; sin embargo, la demanda de los productos biotecnológicos se ha incrementado ante las necesidades de la población, por lo que el uso de tecnologías de modificación genética ha surgido como una alternativa  durante la última década gracias a la capacidad y eficiencia que muestran los métodos como mutagénesis aleatoria, supresión de genes y crispr-cas9. Se propone como objetivo conocer la aplicación del crispr-cas9 en microalgas relacionado con la obtención de productos biotecnológicos de interés industrial. Se determinó que esta tecnología aplicada en las microalgas con uso industrial incrementa la obtención de productos de interés biotecnológico como lípidos, carotenoides, proteínas y enzimas recombinantes.
Vroege christenen en de antieke wijsbegeerte
Authors: Meijering E.P.
Published: March 2024

Early Christian theologians judged pagan philosophy from a position of superiority: they had God’s truth as revealed in Scripture. The pagans possessed a partial knowledge of the truth. Christian theologians were the least negative about Plato’s philosophy. They rejected his doctrine of pre-existence of the soul and of creation from chaotic matter, but welcomed his doctrines of life of the soul after death and of the good Creator. The Platonic view on time and eternity influenced their doctrine of the Trinity. Christian theologians argued that even as Israel took gold and silver vessels with them when they left Egypt, so they were justified in using pagan philosophy to the glory of God.
Smart Economy: The Analysis of Youngpreneurs Development towards the SMEs in East Java Province
Authors: Satria Dias , Wibowo Joshi Maharani , Zahro Fatimah
Published: March 2024

AbstractEast Java Province is one area in Indonesia with many potentials in the creative industry sector, especially SMEs. Unfortunately, SMEs growth in East Java Province is relatively slow because most of them still do not use technological tools. The reason is, SMEs is not attractive enough to the millennial generation and are still not digitized. This research was conducted to determine SMEs' potential digitalization to attract the millennial generation's interest in SMEs. The result showed three main obstacles to applying technology tools in the SMEs industry: marketing networking, branding and packaging, and product standardization. Apart from the obstacle, there are also three essential things to increase their interest in SMEs sectors, which are:  SMEs community; local materials distribution; and optimization of the entrepreneurial mindset. A smart economy strategy can become a long-term economic investment to overcome every obstacle and stimulate the growth and Youngpreneur interest in the SMEs industry. Keywords:Millenial Generation, Smart Economy, SMEs
Underpricing And Herding Behaviour Ipo Stock In Covid-19 Pandemic At Indonesian Stock Exchange
Authors: Kewal Suramaya Suci , Putranto B Yohanes Andri
Published: March 2024

AbstractThis study aims to empirically test whether there is underpricing and herding behavior in companies that have just IPO on the Indonesia Stock Exchange in 2020. The selection in 2020 is because the stock exchange experiences high trading volatility due to the crisis impact of the Covid-19 pandemic. This study uses a market adjusted return approach in calculating underpricing, and uses the Chang, Cheng, and Khorana (CCK) method to indicate the occurrence of herding behavior in IPO shares on the Indonesia Stock Exchange. The significance level used in the study was 5%. The results show that there is an underpricing phenomenon in companies whose IPOs are on the IDX and there is no evidence of herding behavior by investors on IPO shares on the IDX. Investors are advised to invest in IPO shares, especially during the pandemic and make rational considerations in making investment decisions in the capital market. Keywords:  Underpricing, Herding Behavior, IPO Shares, Pandemic, Capital Market
BUM Desa (Village-Owned Enterprises) Accessibility Analysis in Accelerating Village SDGs Achievement
Authors: Rahmawati Emma , Faubiany Varenna , Nababan Febrina Elia
Published: March 2024

AbstractThe accessibility of BUM Desa is related to the development of BUM Desa, which is also one of the driving factors towards achieving the Village SDGs. This research aims to analyse the accessibility of BUM Desa in accelerating the achievement of Village SDGs. The research approach uses quantitative. The results showed that there is a valuable and circumstantial connection between the accessibility of BUM Desa and the development of BUM Desa. In addition, it was obtained that BUM Desa with "Basic" development status has poor accessibility (93.3%), while BUM Desa with "Developing" development status has a better level of accessibility (66.7%). Likewise, BUM Desa with “Advanced” development status has excellent accessibility (60%). The development of BUM Desa is related to the 8th Village SDGs "Equitable Village Economic Growth". To accelerate the achievement of Village SDGs Goals, interventions related to BUM Desa accessibility are needed. Keywords:Accessibility, BUM Desa, Village SDGs, Bogor Regency
Academic Staff Performance in the Post Covid-19: Study of Motivation, Work Environment, and Discipline
Authors: Sumarni Tri , Yuliana Lia , Mamengko Rullyana Puspitaningrum
Published: March 2024

AbstractThe study examines how motivation, work environment, and discipline affect academic staff performance at Universitas Negeri Yogyakarta (UNY) following the COVID-19 pandemic. Using parametric statistics, it involved 191 participants in this ex-post facto quantitative research study. According to the study, motivation, work environment, and discipline all positively and significantly affect the performance of the UNY academic staff. The novelty of this study is that when employees switch from working from home to the office, it affects their motivation, the work environment, and their ability to be disciplined because of worries about the virus resurfacing. The urgency of this study is that UNY is changing from a Public Service Agency to a Legal Entity State University, so to help prepare better human resources, it needs to collect actual information. The study results are explained in more detail, along with some suggestions and implications. Keywords:Motivation, Work Environment, Discipline, Work Performance, Academic Staff
Peace in Religious Teachings and its Impact on Economic and Political Stability
Authors: Abdul Rahim Hafizah , Rahman Asmak Ab
Published: March 2024

AbstractThis study aims to delve into the values of peace within Islam, Hinduism, Buddhism, and Christianity in Malaysia and its profound influence on the country's economic and political stability. This study employs a qualitative approach, utilising both primary and secondary sources. In-depth interviews were conducted with religious leaders representing Islam, Hinduism, Buddhism, and Christianity, while relevant documentation was used as a secondary source. The findings indicate the shared emphasis among religious leaders upon cultivating inner peace within their respective faiths. Each religion advocates that spiritual practices foster inner peace, contributing to a harmonious society, nation, and economic resilience. Conversely, neglecting these religious teachings can lead to violence, social issues, and an absence of peace within the country. Therefore, this study posits that peace holds immense significance, urging its integration among believers and indirectly impacting Malaysia's economic development and political stability. Keywords:Value of peace, religious teachings, economic and political stability.
Developing an ISO 45001-based OHSMS for a Bogotá, Colombia real estate and property development company
Authors:   Ingenio Induspymes Research Group, Universidad Cooperativa de Colombia, Bogotá, Colombia, Angulo Daniela , Mesa Lizeth ,   Ingenio Induspymes Research Group, Universidad Cooperativa de Colombia, Bogotá, Colombia, Pérez Ana Leonela ,   Ingenio Induspymes Research Group, Universidad Cooperativa de Colombia, Bogotá, Colombia, Santis Angélica ,   Ingenio Induspymes Research Group, Universidad Cooperativa de Colombia, Bogotá, Colombia
Published: March 2024

Today, many organizations are seeking to implement continuous improvement plans not only to achieve greater economic benefits but also to improve the quality of life for their employees. The importance of reducing and preventing workplace accidents, protecting the health and well-being of employees, and preventing work-related illnesses has increased. This article focuses on the development of an Occupational Health and Safety Management System (OHSMS) for an organization in the real estate and property development services sector in Bogotá. The design of the OHSMS is based on the identification of the deficiencies of the current system and the proposal of continuous improvement, according to the ISO 45001: 2018 standard. The design process included three stages of research: 1. initial diagnosis, 2. hazard and risk assessment, and 3. management system performance assessment with appropriate controls and indicators. This article evaluates working conditions in production and in enclosed spaces, such as offices. The integration of these aspects ensures a comprehensive vision of occupational health and safety in real estate and property development companies. The design of the OHSMS is an essential step towards the continuous improvement of working conditions and the well-being of employees. Compliance with the ISO 45001: 2018 standard aims to ensure a safe and healthy working environment for all members of the organization.
Virtual Reality–Based Neurorehabilitation Support Tool for People With Cognitive Impairments Resulting From an Acquired Brain Injury: Usability and Feasibility Study
Authors: Prats-Bisbe Alba , López-Carballo Jaume , García-Molina Alberto , Leno-Colorado David , García-Rudolph Alejandro , Opisso Eloy , Jané Raimon
Published: March 2024

Background

Acquired brain injury (ABI) is a prominent cause of disability globally, with virtual reality (VR) emerging as a promising aid in neurorehabilitation. Nonetheless, the diversity among VR interventions can result in inconsistent outcomes and pose challenges in determining efficacy. Recent reviews offer best practice recommendations for designing and implementing therapeutic VR interventions to evaluate the acceptance of fully immersive VR interventions.

Objective

This study aims to evaluate the usability and feasibility of a co-designed VR-based neurorehabilitation support tool by conducting multiple proof-of-concept trials in a sample of patients with ABI within a hospital setting.

Methods

A single session deploying custom immersive serious games to train cognitive functions using a new-generation head-mounted display was conducted among a sample of inpatients with ABI. Structured questionnaires were administered at the end of the session to evaluate the usability of the system and the intervention, participants’ familiarity with the technology, and any adverse effects related to cybersickness. Additionally, the training duration while wearing the headset and the demographic characteristics of the participants were considered.

Results

A total of 20 patients with ABI participated in a 1-hour proof-of-concept trial. The mean usability score was 37 (SD 2.6) out of 40, the technology familiarity level was 9.2 (SD 2.9) out of 12, and the Simulator Sickness Questionnaire total score was 1.3 (SD 2). On average, participants wore the headset for approximately 25.6 (SD 4.7) minutes during the intervention. There were no substantial differences in usability and technology familiarity levels based on patients’ etiology or age, with no notable symptoms of cybersickness reported. Significantly strong correlations were noted between cybersickness symptoms and various usability categories, including exposure, motivation, interactivity, task specificity, and immersion aspects. Further, there was a significant association between the intervention time and the number of tasks performed (P<.001). Furthermore, patients who derived enjoyment from VR sessions expressed a heightened interest in incorporating VR into their daily neurorehabilitation practice (P<.001). Moreover, oculomotor issues were found to be highly sensitive to the onset of disorientation sickness symptoms (P<.001).

Conclusions

Through a collaborative approach, this study showcases the usability and feasibility of a VR-based support tool for cognitive rehabilitation among inpatients with ABI. Key components of such interventions encompass a multidisciplinary array of immersive experiences integrating neurorehabilitation principles and serious games techniques.
Intravenous Therapy Error Reduction Systems: A Cost-Effectiveness Analysis of Two Available Solutions versus Gravity Infusion in South Africa. (Preprint)
Authors: Waterson James , Sahni Jeev
Published: March 2024

BACKGROUND

In the Republic of South Africa smart infusion technologies are poorly adopted across health systems due to the sizeable capital spends for equipment, and the higher cost of disposables versus gravity infusion.

OBJECTIVE

We illustrate the estimated costs and expected effectiveness of gravity infusion and alternatives, and identify the Incremental Cost-Effectiveness Ratio between the respective solutions given the risks of wrong patient-wrong IV-medication and dose/rate errors, harm from infusion injuries, and workflow impacts on nursing time.

METHODS

The techniques assessed were:
Gravity infusion administration.
Volumetric Pump with safety software.
Barcode Medication Administration and Volumetric Pump with safety software.
The study took a healthcare system perspective. Patient harm events were expressed as incidence rates per 10,000 infusions. Infusion therapy undertaken in general adult environments was assessed.

RESULTS

There are substantial hidden costs related to harm associated with gravity infusion. Gravity infusion is very labor intensive. Volumetric Pumps with safety software, and barcode medication administration with smart pump technology fall very closely around an ICER of 1.0 even using the most conservative measures of harm and efficiency loss.

CONCLUSIONS

There is no other study in the literature with the scope or transferability of the current study. The study is generalizable as it does not assume ideal conditions. The results might give less clarity on the value of investment in technologies beyond the do-nothing option in very low-wage healthcare systems, but the technologies’ benefits for patients and healthcare workers might qualify them as ‘higher cost-high impact’ solutions.

CLINICALTRIAL

Nil Required
Geological Structure and Perspectives of Oil and Gas Bearing in Neogene Sediments of the Southern Part of the Kuril Island Arc System
Authors: Krikun Nikita , Babenko I. , Talovina Irina , Duryagina Asiya
Published: March 2024

The article reviews the current state of knowledge about the geological structure and oil and gas bearing of the Southern Kurils, supplemented by the results of the authors’ own observations. Expansion of the mineral resource base of remote regions plays an important role for its economic development. The oil and gas content of the Southern Kurils is a subject of debate. Based on the analysis of the data accumulated and obtained by the authors, the geological structure of the southern islands of the Greater Kuril Ridge has been clarified. The Upper Miocene-Pliocene complex has been identified in potentially oil and gas bearing Neogene sediments on the basis of direct and indirect signs, in which lithological and structural traps may be formed. As a result of comparative analysis of prospective deposits of onshore, offshore areas of the Mid-Kurilsk Trough and adjacent objects of the North-West Pacific, rocks of the basement of the island arc are assumed to be oil and gas bearing. The most perspective areas from the point of view of oil and gas potential onshore and offshore have been identified, which are the Kuibyshev Block, Iturup Island, and Kasatka Bay, respectively.