bluuebunny/crossref_metadata_2025 huggingface dataset:
Applications of hydrogel composite multifunctional depots systems in rendering palliative care in otorhinolaryngology
Authors: Charkova Natalia Alexeevna
Published: October 2019

Relevance. Throat cancer is the most widespread malignant tumor of a throat and makes about 3% of all malignant tumors of the person. Bleedings at throat cancer is the most difficult and dangerous complication posing direct threat to life of the oncological patient. An intervention is usually characterized by the expressed painful syndrome in a zone of surgical access for patients with surgical pathology of ENT organs. For that reason, using of gel polymeric dressing means is the most modern and effective. Analgesic action is noted in the area of a postoperative wound within the first 60 - 90 minutes after imposing of such bandage.
Aim of research is to determine efficiency of multifunctional depot-system of the prolonged action on a gel basis of Kolegel-ADL of various degree of viscosity at a tamponade of a throat and trachea for elimination of a local hemorrhage.
Materials and methods. Koletes-ADL dressing was used at treatment of 39 patients with malignant tumors of a throat. Patients arrived in the emergency order with bleedings from a throat, were on hospitalization in acute hospital No. 1, Voronezh. A morphological variety of malignant tumors of this localization took place. The control group has included 19 people with similar destructive and tumorous processes complicated by bleeding treatment of which was carried out by the standard technique.
Results. As criteria of a convalescence considered the speed of reduction of the reactive phenomena in a wound and maturing of young granulations. Such characteristics like high viscosity of hydrogel dressing means, elastic consistency, entered into its structure antiseptics and local anesthetic allow to use it as tampon for a long period. One of essential advantages of use of Kolegel-ADL is creation a barrier impeding penetration of an infection into a skull cavity. The local anesthetic of Lidokin entered into structure of dressing means allows us stop a pain syndrome for a long time that reduces the need for parenteral introduction of anesthetics.
Gauze-based dressings were used in the control group. There was injury to the wound surface when changing bandages, and the remains of gauze fibers in the wound led to inflammation.
Conclusion. Multifunctional depot-system on a gel basis can be recommended as local antiedematous, haemostatic, antiseptic and anesthetic for local treatment of wound process in otorhinolaryngology, for therapy and prevention of purulent complications of wound surfaces of patients with oncological pathology of the throat complicated by bleeding.
Des traces du « moi » professionnel dans le discours d'enseignants de FLE : apports des entretiens d'autoconfrontation
Authors: Domínguez Estefanía
Published: October 2019

Il s'agit dans cet article de mettre en exergue ce que des discours d'enseignants sur leur propre activité enseignante apportent en termes de découverte du « moi » professionnel. Pour ce faire, nous nous basons sur des discours d'enseignantes de français langue étrangère1. Au regard de leurs propos, nous montrerons comment les dynamiques discursives permettent de déceler des paramètres constitutifs de leur pratique enseignante. Nous verrons que les informatrices se (re)découvrent au travers de leurs image, dire et faire, montrant alors des conceptions assumées de leur enseignement mais aussi une partie de leur pratique qui leur échappe dans le vif de l’action, notamment leur voix et leur regard.
Lo que se tiene. El intimismo y otros aspectos de la poesía de Fina García Marruz
Authors: Rangel López Asunción Del Carmen , Solórzano Esqueda Lilia
Published: October 2019

El artículo explora, en su primera parte, sobre la riqueza de la interioridad en algunos momentos de la poesía de la cubana Fina García Marruz, y de cómo ésta se convierte en un assunto que corresponde a los reinos de la poesía. En el primer apartado se intenta sostener que todo momento en que la poeta habla de su reino interior, está aludiendo a algo dicho a propósito de la poesía y, a su vez, a propósito de la vida. En la segunda parte, se revisan algunos momentos de Visitaciones (1970) y Habana del centro (1997), en aras de abordar la construcción de esa Cuba íntima que a la escritora le es fundamental para ser en su poesía. La luz, el tiempo, los retratos de los amigos de la generación emergida alrededor de la revista Orígenes, el azul como color simbólico de la isla, las frutas, los paisajes, la música, son elementos que componen esa singularidad, una especie de patria íntima.
« Je me sers d’animaux pour instruire les hommes » : le personnage-animal dans la littérature d’enfance et de jeunesse contemporaine
Authors: Atzenhoffer Régine
Published: October 2019

Les animaux anthropomorphes peuplent la littérature de jeunesse. L’enjeu de ce travail est de mettre en évidence des apports et impacts de ces héros à poils, plumes et écailles auprès d’un jeune lectorat. Selon son âge, celui-ci sera plus ou moins attiré par un certain type d’animal : l’animalcompagnon du héros humain, l’animal-héros identificatoire ou l’animal-guide et médiateur susceptible d’aider et d’accompagner l’enfant-lecteur dans sa découverte du monde.
La ponctuation dans quelques imprimés de Galliot du Pré
Authors: LI Huei-Chen
Published: October 2019

D’après Annie Charon-Parent, Galliot du Pré, libraire-éditeur du XVIe siècle, publie 330 éditions durant sa carrière, entre 1521 et 1561. Elles touchent essentiellement le droit, la littérature, l’histoire, la religion, les sciences, ainsi que la géographie. Comme nous le savons bien, la ponctuation a pour principale fonction de rendre le texte plus intelligible et d’aider le lecteur à repérer le sens des phrases et la structure du texte : cette fonction de rendre le texte clair répond parfaitement au goût des humanistes. Pourtant, face à l’anarchie et à la variabilité de la ponctuation médiévale, la pratique de la ponctuation renaissante, avec l’avènement de l’imprimerie, est-elle plus stable que celle du Moyen Âge ? Respecte-elle les règles recommandées par les traités médiévaux ou ceux de l’époque ? Notre étude, basée sur trois imprimés de Galliot du Pré parus entre 1522 et 1530, tous conservés à la BNF (Rés. Y2-72 ; Rés. Y2-31 ; Rés. Y2-74), vise à présenter les pratiques de chaque imprimé afin de mettre au clair le sous-système de Galliot du Pré, un homme de la Renaissance.
Neología e identidad lingüística en el español de México
Authors: Zacarías Ponce de León Ramón Felipe
Published: October 2019

Desde un punto de vista onomasiológico, el proceso de acuñación de nuevas palabras está determinado por aspectos socioculturales e identitarios de las comunidades lingüísticas (Štekauer 2005; Körtvélyessy y Štekauer 2014). En el desarrollo de una cultura, la creación de léxico secundario está estrechamente relacionada con el devenir histórico y social de los pueblos. No debe sorprender que en las variedades dialectales de la lengua española puedan encontrarse distintas preferencias en la selección de los esquemas de formación de palabras utilizados para nombrar el mundo. En este artículo, analizaremos los procesos lexicogenésicos del español de México y mostraremos que algunos son propios de esta variedad del español y reflejan aspectos actuales de su sociedad y su cultura. Recurriremos al corpus neológico Morfolex (Zacarías, 2016c), que recopila neologismos formados en México en la última década. Se describirán brevemente los procesos de recolección y clasificación de neologismos y los criterios de productividad que permiten reconocer los esquemas de formación de palabras favoritos. Finalmente, se mostrará que entre los esquemas formativos más productivos y que identifican la variante mexicana se encuentran los sufijos azo, iza, erío; el elemento compositivo narco; las palabras compuestas de nombre y adjetivo, y los cruces léxicos.
Reconstructing and re-defining the space: Living in between the slum and the tourist destination
Authors: Ismanto Manggala , Martias Irsyad , Sutowo Reza , Noviar Rizal
Published: October 2019

Efforts to reconstruct landscapes and living spaces occur in cities, especially in urban slums. This effort is not only carried out by the settlers but also by external actors who have the intention to improve their lives. It is interesting to see the encounter between actors, especially regarding how negotiations occur between their interests. Jodipan Village becomes one of the slums areas in Malang which make efforts to define and reconstruct the space of their living space by re-colouring the neighbourhood landscape. By the collaboration of various stakeholders such as private parties and the civil society, the village space redefined into a tourist destination that attracts tourists to visit. We gathered a set of information from six local people, one public official, and two team members of Guyspro. Nowadays, Jodipan is popularly known as Kampung Warna-Warni Jodipan or Jodipan Colorful Village (KWJ). The spatial changes which rise from the grass-root provide the opportunities and challenges for the community to negotiate the process of the urban planning implementation in Malang. As a result, the slum stigma has been alleviated and the public acknowledgements that Jodipan Village is being a tourist destination, giving a chance to the settlers to gain their right to live in Jodipan Village area. With this thematic village, the community learns to manage their assets independently by creating a management team that manages the printing of ticket passes, repainting and organising parking lots that benefit local people.
PENGARUH GAYA BELAJAR TERHADAP PRESTASI MAHASISWA GENERASI Z DI PERGURUAN TINGGI
Authors: Nur Habibah  , Rahmawati Siti , Sayekti Andita
Published: October 2019

Generasi Z saat ini mendominasi dan mulai memasuki fase perguruan tinggi. Generasi ini memiliki karakteristik yang unik yaitu cepat beradaptasi dengan perkembangan teknologi yang ada. Karakter tersebut tentunya memengaruhi gaya belajar setiap individu. Penelitian ini bertujuan untuk (1) mengetahui karakteristik mahasiswa generasi Z (2) menganalisis pengaruh gaya belajar terhadap prestasi mahasiswa generasi Z (3) rekomendasi pembelajaran untuk Departemen Manajemen. Responden pada penelitian ini adalah mahasiswa Departemen Manajemen FEM IPB angkatan 2015-2018. Metode pengambilan sampel yaitu Nonprobability Sampling dengan teknik Purposive Sampling. Data yang digunakan dalam penelitian ini adalah data primer dan sekunder. Alat analisis yang digunakan adalah analisis deskriptif dan SEM-PLS menggunakan Smart Pls 3.0. Hasil penelitian menunjukkan bahwa gaya belajar auditori memengaruhi prestasi secara signifikan.
PENGARUH PENGGUNAAN METODE MIND MAPPING TERHADAP PENINGKATAN PEMAHAMAN KONSEP BELAJAR SISWA KELAS VII SMP NEGERI 2 DEPOK, SLEMAN, YOGYAKARTA
Authors: Prianda Muhammad Alif , Wahyono Sugeng Bayu
Published: October 2019

Penelitian ini bertujuan untuk mengetahui pengaruh pada metode pembelajaran mind mapping yang berguna untuk meningkatkan pemahaman konsep kepada siswa pada materi “Potensi Sumber Daya Alam dan Kemaritiman Indonesia” terhadap siswa kelas VII D SMP Negeri 2 Depok, Sleman, Yogyakarta. Jenis penelitian yang digunakan adalah penelitian eksperimen pre-experimental designed dengan model one group pretest and posttest, subjek dari penelitian ini adalah siswa kelas VII D yang berjumlah 32 orang siswa. Teknik pengumpulan data pada penelitian ini menggunakan tes, observasi, dan dokumentasi. Instrument yang digunakan dalam pengujian penelitian ini adalah tes pilihan ganda. Teknik analisis yang digunakan adalah dengan membandingkan rata-rata pretest dan posttest serta uji hipotesis dengan t-test menggunakan taraf signifikan 5%. Hasil penelitian ini menunjukan adanya pengaruh yang terjadi pada metode pembelajaran mind mappng yang diberikan, terhadap peningkatan pemahaman konsep siswa dikelas VII D. Pengaruh tersebut terbukti dengan perbedaan yang signifikan antara rata-rata skor pretest dan rata-rata skor posttest. Yaitu skor rata-rata pretest sebesar 74,75 dan skor rata-rata posttest sebesar 83,63 hal tersebut terbukti pada pengujian t-test dengan hasil perhitungan thitung > ttabel yaitu 5.834 > 2,040 ini membuktikan bahwa kemampuan dalam memahami konsep materi siswa kelas VII D meningkat dengan  treatment berupa metode pembelajaran mind mapping.
Development of E-Practicum Module for Pharmacy Physics Learning
Authors: Dhina Meiry Akmara , Hadisoebroto Ginayanti , Mubaroq Sugeng Rifqi
Published: October 2019

This research develops learning methods through the development of teaching materials. In addition to this study developes an e-practicum module in one of the subjects in the pharmacy department, namely physics pharmacy. Today, the physics pharmacy practice uses printed module practice in the form of module books. This research intends to make innovation in practical learning. Current educational innovations that are developing in technological innovations, one of which is information technology. The use of information technology is very fast and sophisticated, currently technological computer-based has been developing with software applications that also continue to fulfil the world's needs. The development of this electronic technology can be utilized in educational innovations in practice methods. The printed module practice was developed into a web-based electronic practicum module. The method used in this research is the waterfall model which consists of the main stages of needs analysis, system and software design, system implementation and testing as well as a maintainance. The results of this study are a web-based module-practice named E-mulsi which can be accessed via e-mulsi.com. This application has been tested in one of the pharmacy physics classes and has received positive responses from users not only students but also lecturers because it is easier to use modules and preparation of technology-based reports.
A chronostratigraphic framework for the Upper Jurassic Morrison Formation, western U.S.A.
Authors: Maidment Susannah C.R. , Muxworthy Adrian
Published: October 2019

The fluvial, overbank, and lacustrine deposits of the Upper Jurassic Morrison Formation of the Western Interior, U.S.A. have been intensively studied due to their diverse and well-preserved dinosaurian fauna, and the presence of economic quantities of uranium and vanadium ores. The formation crops out over 12 degrees of latitude and 1.2 million km2, and is an excellent case study for the examination of paleoecology, community structure, and evolutionary dynamics at a time in Earth's history when the climate was significantly warmer than today. However, paleoecological studies have been hampered by lack of correlation across the formation. Assuming a primarily tectonic control on fluvial architecture, we propose the first chronostratigraphic framework of the formation, which is based on sequence stratigraphy, magnetostratigraphy, and radiometric dating. The formation can be divided into three sequences each represented by a period of degradation followed by aggradation. This chronostratigraphic framework indicates that the formation youngs to the north, and was deposited over about 7 million years during the late Kimmeridgian and Tithonian. This framework provides a foundation for future sedimentological, stratigraphic, and paleobiological studies of the iconic dinosaurian fauna known from the Morrison.
The ways to ensure fatigue strength of cold-formed rebars. Foundry production and metallurgy
Authors: Belash V. V. , Akhmetov T. A. , Oborov M. V.
Published: October 2019

To ensure safe operation of buildings and structures from reinforced concrete, European norms set requirements for its fatigue strength (resistance). Tests are carried out with oscillation swing amplitude 2sa from 150–200 MPa. Rebar shall withstand from 1 to 2 mln. cycles.

The analysis of causes which decrease the fatigue strength of cold-formed steel is made in the article. Fatigue strength is a lot affected by surface defects and stress concentrators. Filler transition in the point where transversal rib crosses a rebar body becomes as a rebar stress concentrator. To detect details of early breakage, analysis the condition of fracture in the area of thickened (marking) ribs was made. Sequence of rebar breakage was established as well as the initial point of a crack creation was detected. This fracture is characterized as a fatigue one, with clear zones of fatigue fracture having fine-grained surface and static fracture zone– the rest of section with fibrous structure. While applying a bar mark, smoothness of filler transition was disturbed in the crossing point where transversal rib crosses a rebar body, and this action caused decrease of fatigue strength of cold-formed rebar.

The article describes research on development of requirements for rolling tools used in production of cold-formed rebars.

Use of information given in this article during design, purchasing and manufacture of the equipment will allow to minimize factors which have negative influence on rebar’s fatigue test results.
Special aspects of the measurement of the internal geometric parameters of the channel parts of small size
Authors: Zakhorevich S. V. , Borisovets I. V. , Lazebnikova I. P.
Published: October 2019

Technical measurements of linear-angular sizes of parts and products are the most common in mechanical engineering and make up to 95% of the measurements of all controlled sizes. Measuring control is an integral part of each operation of technological processes of production, assembly, testing of products. The complex method of measuring the external and internal geometric characteristics of a carbide die, given in the article, allows to measure the geometric parameters of small-size parts and to give a final assessment of the product for compliance with the requirements of the project technical documentation.
Study of the effect of the application of the double finish drawing die on the plastic properties of steel high carbon wire
Authors: Evdonich V. A. , Bobarikin Yu. L. , Martianov Yu. V. , Akhmetov T. A.
Published: October 2019

The possibility of application of the double finishing drawing die at the stage of fine-drawing in the manufacture of steel metal cord 2x0 30SHT is сontemplated. As a result of the performed studies, a numerical finite element model of wire drawing in a serial finishing single fiber and in an experimental double finishing fiber has been developed. The obtained distribution of effective plastic deformation in the wire during drawing shows that when drawing in a double fiber, there is a higher uniformity of deformation in the direction of the radius of the wire along the cross section located at the outlet of the die. The distribution of effective stresses in the wire when drawing shows that when drawing in a double fiber, there is a more uniform distribution of effective stresses in the direction of the radius of the wire along the cross section located at the outlet of the die.

Further experimental tests performed at the drawing mill NT 12.4 in StPC-1 showed that the use of double dies allowed to increase the plastic properties of the wire 0.30 SHT, manifested in technological tests by increasing the number of reversible twists of the wire from 7 to 78 and reducing the ratio of yield strength to tensile strength decreased from 95 to 91.
Assessment of the possibility to use the of hot dip galvanizing waste-zinc dust for zinc-rich paints
Authors: Urbanovich N. I. , Baranovsky K. A. , Rozenberg E. V. , Ashuyko V. A.
Published: October 2019

The chemical and grain-size analysis of zinc dust – waste of hot – dip zinc plating were made. The research results showed that zinc dust is a dispersed waste with particles of mainly circular shape and sizes from 3 to 200 microns, and in chemical composition it mainly meets the requirements of ISO 3549. The presence of lead in the zinc dust composition, which is slightly higher than the acceptable level will be taken into account in the development of zinc-rich paints compositions. Analysis of the results of sieving of zinc dust showed that it contains particles of size £15 µm, which is about 27% of its fractional composition and which can be recommended for the manufacture of zinc-rich paints.
Testing of the physical and mechanical properties of cast iron with the help of IFMH-C device
Authors: Kren A. P. , Rudnitsky V. A. , Lantsman G. A. , Delendik M. N. , Zinkevich N. V. , Hnutsenka E. V.
Published: October 2019

The possibility of the application of impact microindentation method for testing the physic and mechanical properties of cast iron using the IFMH-C instrument developed at the Institute of applied physics of the National Academy of Sciences of Belarus was tested. It was established that the method and the instrument allow to estimate such parameters as Brinell hardness in the range of 100–500 HB, elastic modulus from 40 to 200 MPa, as well as to determine the tensile strength of the flake and spheroidal graphite cast irons. The possibility of using the instrument for non-destructive test directly of parts and products in the manufacturing environments is shown.
Advanced materials used for development of lubricated compositions for die casting
Authors: Mikhaltsov A. M. , Pivovarchyk A. A. , Skaskevich A. A.
Published: October 2019

The article presents the requirements for the lubricants used in die casting of non-ferrous alloys and polymer materials. The methodology for conducting research to determine the lubricating properties of materials, as well as the results of studies of the lubricating qualities of materials used in the development of lubricant compositions for die casting of non-ferrous alloys and polymer products are presented. It is shown that the use of the materials researched under study reduces the effort to extract the metal rod from the casting by 4.5–8.9 times. It has been established that it is advisable to use petroleum jelly and fus (by-product of vegetable oil) as materials used to develop the composition of a lubricant for die-casting non-ferrous alloys and polymer products. The lubricity of these materials is, on average, 28.8–51.2% higher than that of other lubricants studied.
Evaluation of plasticity during deformation of carbon steel
Authors: Fetisov V. Р.
Published: October 2019

The indicator of the degree of relative reduction of the cross-sectional area and the indicator of the degree of development of the necking, more sensitive to changes in the structural parameters and the deformation temperature of carbon steel compared to the traditional were proposed in comparison with the relative contraction and the true deformation index. The role of relaxation of internal stresses and increased mobility of dislocations in the formation of plastic properties of carbon steel is considered.
The increase in turnover of steel-teeming ladles with a combined lining at the steelmaking production in OJSC «BSW – Management Company of Holding «BMC»
Authors: Artamoshin A. L. , Turygin A. K. , Khvesenya D. N.
Published: October 2019

Currently, there is a need to increase the turnover of steel-teeming ladles ESPC-1,2, in connection with which the actual question was to reduce the duration of preparation of steel ladles to work. On steel ladles with a combined lining, one of the solution to this problem is to reduce the duration of drying and heating of the concrete working lining, but there is a risk of «undermining» the concrete mass due to the rapid warming of temperature. During the tests of the concrete mass from the manufacturer «A» for the period 2016–2018 the duration of drying and heating was reduced from 52 to 37 hours. Average overhaul life and durability of the concrete lining has increased by 37% and amounted to 96 meltings.
The effect of different types of ageing on adhesive properties of steel cord. Salt aging
Authors: Khrol O. N.
Published: October 2019

The development of the world automotive industry is aimed at creating new, both in design and properties of tires that can operate in high dynamic loads under different operating conditions. The most probable cause of aging of automobile tires is considered in the article; one of methods of laboratory tests for the accelerated aging of system rubber-metal cord is described. The dependence of the influence of the metal cord design on the adhesion characteristics of the rubberized metal cord and its resistance to aging is also analyzed.
Naturally Occurring Asbestos in Valmalenco (Central Alps, Northern Italy): From Quarries and Mines to Stream Sediments
Authors: Cavallo Alessandro , Petriglieri Jasmine Rita
Published: October 2019

The Valmalenco area (central Alps, northern Italy) is an excellent case study for naturally occurring asbestos (NOA) because of the huge outcrops of serpentinites and widespread quarrying and mining activities. Extensive sampling of rocks, soils, stream sediments, and airborne asbestos has been in progress since 2004. The combined use of scanning electron microscopy and transmission electron microscopy has proven to be effective for the correct discrimination between asbestiform and non-asbestiform mineralogical varieties (but falling into the World Health Organization fiber definition), whereas phase contrast microscopy has not proven suitable because of the very small size of fibrils after strong mechanical fragmentation. The quantitative analysis of “massive” samples (rocks, soils, and sediments) requires accurate and representative sampling as well as specific counting and discrimination criteria to determine NOA. Over a decade of experience has allowed us to identify critical issues and adopt effective preventive measures.
Management of Naturally Occurring Asbestos Area in Republic of Korea
Authors: Yoon Sungjun , Yeom Kyubong , Kim Yongun , Park Byungno , Park Jaebong , Kim Hyesu , Jeong Hyeonyi , Roh Yul
Published: October 2019

The Republic of Korea Government has adopted a whole-of-government approach in the management of naturally occurring asbestos (NOA) through a nationwide asbestos management plan. Regional and detailed mapping, and examination of NOA effects are still ongoing for NOA management by indoor air, noise and asbestos management division, Ministry of Environment. Plans by the Korea Rail Network Authority are under way to rebuild the Janghang double-track railway. The proposed Jannghang double-track railway route is through an area of high NOA probability that has serpentine and ultramafic rock. Chrysotile, tremolite, and actinolite asbestos were among the rocks identified within the project site (initial planning line and the operational design line). The level of asbestos in most soils was low (≤0.25 percent), while some soils contained 0.75 percent asbestos. Monitoring and analyses of air quality revealed below 0.01 fibers per cm3 (f/cc). However, there were no traces of asbestos detected in the groundwater and stream water. Despite the low asbestos content of the soil and rock, the disturbance of NOA-containing soils and rocks during railway construction could trigger the release of asbestos fibers into the air. NOA mitigation plans and measures are necessary for workers and residents during the construction of the railway.
Unleashing Full Production Potential of Mature-Water Coning Sensitive-Oil Field through Simple Reservoir Simulation and Artificial Lift Installation
Authors: Alfarizi M. Arief , Aryanto Agus , Sukotrihadiyono Tejo , Ghozali Farid , Febrianto Dwi Hudya , Tri P. Wahyu Priantono , Ananda P. Rizki , Luqman _Luqman , Faris B. Ferry , Arseto Yoseph Itok
Published: October 2019

X field was discovered in 2001 and started producing in 2003. The formation is limestone supported with large aquifer. Main challenge is that wells must be produced with critical rate limitation, if a well is produced too hard, water coning and water breakthrough can occur, then oil production will disappear, as happened in one of X's well. In 2011, several wells were becomes ceased-to-flow due to an increase in watercut value, then pumping units were installed on these wells. However, due to recurrent mechanical downhole problems which limit effective production days, a new initiative is required to overcome these issues. After thorough analysis, ESP was chosen as best-fit artificial lift considering its versatility in deviated wells and high deliverability. In 2017, pilot phase of ESP implementation started in X-D4 well, which gave 150 BOPD average oil gain. Learning from the success of X-D4, comprehensive production strategy using ESP is considered crucial for optimum recovery.

To support this strategy, an integrated optimization study with reservoir simulation model was used instead of analytical method to obtain more reliable production forecast. History matching was carried out from initial production data in 2003, a good match in liquid-oil-water-pressure data was successfully obtained, but poor match was occurred on gas production rate, this was ignored due to high uncertainty on gas measurements. The outcomes of simulation study were ESP well candidates, optimum production rate target and proper timing of ESP installation. The next step was the preparation of ESP which consists of the design and procurement of ESP. Following the ESP installation plan, it was also decided to increase power generation capacity at current surface facilities.

Currently, 7 out of 10 ESPs have been installed. Power plant upgrading and overhead line installation to support ESP have also been carried out. The average oil gain obtained was 700 BOPD with cumulative of 160 MBO (from 2017 – until 2018). This optimization case will contribute 1.5 MMBO additional reserve from "do nothing" case. Economic evaluation shows a very good viability with significant additional gross revenue.

This optimization project has succeeded in reducing oil deferment from ceased-to-flow wells and extending the field's life. Good collaboration between each part (subsurface and surface) in this project has succeeded in producing significant oil gains. Continuous monitoring is still needed to further match optimization forecast with actual conditions. Long-term plans, some improvements are still needed in the reservoir model, one of which is OOIP value, there is a possibility that the actual X OOIP is bigger than the one in the reservoir model.
Two SNPs rs1801133 and rs1801394 in folate pathway are associated with the risk of nonsyndromic cleft lip with or without cleft palate
Authors: Author) Qiuyan Li(Former Corresponding , Xu Lidan , Jia Xueyuan , Saleem Komal , Zaib Tahir , Sun Wenjing , Author) Songbin Fu(New Corresponding
Published: October 2019

Background Prenatal intake of folic acid is important for prevention of nonsyndromic cleft lip with or without cleft palate (NSCL/P). Associated genes in folate pathway are major enzymes of folic acid metabolism that is crucial for preventing birth defects. The present study aims to investigate the association between four single nucleotide polymorphisms (SNPs) in folate pathway genes and the risk of NSCL/P.
Methods Comprehensive bioinformatics analysis was used to predict the functional pathogenicity of genetic variation. The PubMed, Embase database and Google Scholar were intensively searched by two researchers to ascertain all relevant studies. Stata 11.0 software was used to analyze the results. Subgroup analysis was carried out to assess the influence of genetic background. Sensitivity analysis, regression analysis and publication analysis were also conducted to enhance the strength of our results.
Results It is estimated that the probability of two missense mutation rs1801133 in MTHFR and rs1801394 in MTRR are more likely to be damaging by bioinformatics analysis. A total of 34 publications were included in the present study analysis. Our results showed a significant association between rs1801133 and risk of NSCL/P in two genetic models: TT allele vs CC allele (OR=1.333 95%CI=1.062-1.674, P =0.013), and recessive model (OR=1.325 95%CI=1.075-1.634, P =0.008). A significant association between rs1801394 and the risk of NSCL/P in Asian (GG allele vs AA allele, OR=0.520 95%CI=0.321-0.841, P =0.008) was also observed. Meta-regression, sensitivity analysis, and publication bias analysis confirmed that the results of the present study were statistically significant.
Conclusions The present study highlights two SNPs rs1801133 in MTHFR and rs1801394 in MTRR, associated with the increasing risk of NSCL/P. Further, larger studies should be performed to confirm these findings.
Efficacy of ultrasound-guided rectus sheath block, butorphanol for single-incision laparoscopic cholecystectomy: A prospective, randomized, clinical trial
Authors: Fu Huimin , Zhong Chaochao , Gao Yongtao , Xu Xingguo
Published: October 2019

Background: Whether rectus sheath block (RSB) combined with butorphanol can relieve incision pain and visceral pain in patients undergoing single-incision laparoscopic cholecystectomy (SILC) remains unknown. The goal of this study was to assess the efficacy of ultrasound-guided bilateral RSB, butorphanol on postoperative analgesia in patients undergoing SILC.
Methods: All 116 patients who met the criteria were randomly divided into four groups: (Ⅰ) (n=29) general anesthesia combined with patient controlled intravenous analgesia (PCIA) (sufentanil 100ug); (Ⅱ) (n=29) general anesthesia combined with PCIA (butorphanol 8mg); (Ⅲ) (n=29) ultrasound-guided RSB combined with PCIA (sufentanil 100ug). (Ⅳ) (n=29) RSB combined with PCIA (butorphanol 8mg). Outcomes included visual analog scale (VAS) scores of incisional and visceral pain at rest and cough at 2,6,12 and 24h postoperatively, if a patient’s pain score＞3, then butorphanol 2mg was administered intravenously. the dose of butorphanol and opioids, the pressing numbers of PCIA, the length of hospital stay and the incidence of postoperative adverse events.
Results: Both rest and cough pain scores were lower during first 2,6 hours in group Ⅲ than groupⅠ, similarly, group Ⅳwas significantly lower than groupⅡ. GroupⅠneeded more butorphanol as rescue analgesic for pain relief than group Ⅲ, group Ⅳ was better than group Ⅱ. In the above pairwise comparisons, it was clear that group Ⅲ and group Ⅳ had lower VAS scores. VAS scores of visceral pain was lower in groupⅡ at 2, 6 and 12 h after surgery compared with the groupⅠ. In the both groups Ⅲ and Ⅳ, the group Ⅳ was also lower than groupⅢ. Overall, RSB combined with PCIA (butorphanol 8mg) is the best match.
Conclusions: Ultrasound-guided RSB combined with butorphanol can provide sufficient pain treatment after SILC.
Trial registration: The study was registered prospectively with the Chinese Clinical Trial Registry（reg no.ChiCTR1900020738), obtained ethics committee of Affiliated Hospital of Nantong University approval (approved number: 2018-K067).
Zoonotic Escherichia coli is a potential Driver of Antimicrobial Resistance among Pastoralist Communities in Uganda: A Laboratory based Cross sectional Study
Authors: Walusansa Abdul , Iramiot Jacob Stanly , Najjuka Florence , Kajumbula Henry , Asiimwe Benon
Published: October 2019

Background Non-prescribed use of antimicrobials in Agriculture incurs a transfer risk of resistant pathogens to humans, complicating treatment. The aim of this study was to determine the potential of Zoonotic E. coli to serve as drivers of antimicrobial resistance among animals and humans in pastoralist communities in Kasese district, so as to protect the community.Materials and methods A laboratory based cross-sectional study was done using archived E. coli isolates previously obtained from humans in pastoralist communities of Kasese district, Uganda. Recovery of the isolates was done by conventional culture, and Identification by biochemical methods, serotyping and PCR. Antimicrobial resistance profiling was done by using Kirby Bauer disc diffusion method. The isolates were also screened for resistance mechanisms including Extended Spectrum β-lactamase (ESBL), Carbapenemase and AmpC production using disc diffusion based methods.Results The prevalence of Enterohemorrhagic E.coli (EHEC) was 16% (28/180). These EHEC isolates belonged to phylogroups; B 1 (94%, 26/28), B2 (3%, 1/28) and A (3%, 1/28). The most prevalent virulence gene was Stx1 (100%, 28/28) followed by Stx2e (94%, 26/28); none of the isolates was Stx2 positive. Highest resistance was seen to Cotrimoxazole (89%, 25/28), Tetracycline (71%, 20/28), Ampicillin (65%, 18/28) and Nitrofurantoin (28%, 8/28), these are the most commonly used antimicrobials in the agricultural sector in Uganda. Minimal resistance was observed to the antimicrobials that are commonly used in human medicine especially β-lactams, β-lactam+inhibitors and Carbapenems. Of the 28 zoonotic E. coli isolates, 17%, (5/28) were ESBL positive and among these 1 (3%, 1/28) was a Carbapenemase producer.Conclusion There is a high prevalence of highly pathogenic and resistant zoonotic E. coli among humans in pastoralist communities in Uganda. We suspect that these pathogens, along with their AMR genes, were acquired from animals because they largely contained the animal specific Vero toxin gene VT2e and majority belonged Pylo-group B 1 which has been documented as the most common EHEC phylo-group inhabiting domestic animals. We recommend that studies involving relatedness of drug resistant isolates from humans and animals should be conducted to ascertain the role of enterohemorrhagic E. coli in the zoonotic spread of antimicrobial resistance in pastoralist communities.
Stopping smoking advice given by practice assistants after routine cervical screening in general practice: a qualitative exploration of potential barriers and enablers.
Authors: Mansour Marthe B.L. , Crone Matty R. , Weert Henk C. van , Chavannes Niels H. , Asselt Kristel M. van
Published: October 2019

Background Cervical screening could be an appropriate moment to provide female smokers with stopping smoking advice and support. In Dutch general practice cervical smears are performed by practice assistants. The aim of this study was to identify potential barriers or enablers for a stopping smoking strategy performed by trained practice assistants after routine cervical screening. The strategy consists of brief stopping smoking advice and is based on the Ask-Advise-Connect approach.Methods Three focus group meetings were held with 10 practice assistants, 3 nurses, and 6 general practitioners. We analysed data using thematic analysis. Identified factors are presented within the framework of the Social Ecological Model.Results Potential influential factors were identified at individual, interpersonal, and workplace levels. At the individual level: practice assistants did not see themselves as having a professional role in a smoking cessation program. While they could register smoking status, they were reluctant to provide advice. However, practice assistants valued having advice at hand in order to make relatively young female smokers aware of the health risks At the interpersonal level: practice assistants thought that their relationship with the women would change if they gave stopping smoking advice. Moreover, the assistant’s own attitude to smokers and her beliefs about the smoker’s willingness to change behaviour could influence the relationship. At the workplace level: the availability and motivation of nurses might hamper referral. The general practitioners’ opinion about primary prevention and smoking cessation could influence the amount of support given to practice assistants when it comes to providing stopping smoking advice.Conclusions At individual, interpersonal, and workplace levels, several factors could influence the provision of a stop smoking strategy by a practice assistant. These factors could be used to design a behavioural change intervention to be provided by practice assistants after cervical cancer screening.
Anxiety and depression in patients with chronic cardiovascular disease—factors differentiating rural and urban subpopulations
Authors: Szlenk-Czyczerska Elżbieta , Guzek Marika , Prusaczyk Artur , Bielska Dorota Emilia , Ławnik Anna , Polański Piotr , Kurpas Donata
Published: October 2019

Background. People suffering from cardiovascular diseases (CVD) increasingly experience depression and anxiety disorders. Therefore, it is essential to improve identification strategies and methods of coping for these conditions.Objectives. The aim of the study was to analyse selected variables differentiating rural from urban populations as well as identify potentially increased levels of depression and anxiety.Material and methods. The study was carried out in 193 CVD patients home-cared by a district nurse. Results. Women constituted the majority of respondents (71.7%, n = 81 City-C vs 65.8%, n = 50 Village-V). The median age of the C patients was 76 (range 17-101) vs. 72 (range 18-94) for the V patients. The correlation coefficients displayed significant differences in anxiety, number of cardiologist visits (p = 0.005) and interventions provided by a district nurse (p = 0.03). The rural population stood out in number of home visits, age, assessment of needs and QoL. In addition, a strong relationship between anxiety and age was noted in the rural population (1/OR=1.04; 95% CI: 0.91–0.99), the assessment of satisfied needs (1/OR=293.86; 95% CI: 0.00001–0.56), depression (OR=5.85; 95% CI: 1.58–25.66), QoL in physical (OR=1.56; 95% CI: 1.11–2.33), social (1/OR=1.53; 95% CI: 0.04–0.94) and environmental domains (OR=1.67; 95% CI: 1.06–3.00) as well as between depression and anxiety (OR=4.60; 95% CI: 1.45–16.28), QoL in physical (1/OR=1.39; 95% CI: 0.50–0.97) and psychological (OR=1.37; 95% CI: 1.01–1.93) domains.
Secondary health conditions and their impact on the wellbeing of people with spinal cord injury, South Africa: Patients perspective.
Authors: PILUSA SONTI , Hellen Myezwa , Joanne Potterton
Published: October 2019

Background Long-term rehabilitation that includes preventive care for people with spinal cord injury is key to promoting health. There is evidence that secondary health conditions (SHCs) are prevalent complications across the continuum of care for people with spinal cord injury, leading to recurrent hospitalization and poor quality of life. In order to develop a context-based prevention model of care and strategies in South Africa, there is a need to understand the lived experiences of people with spinal cord injury (SCI).Aim To describe people with spinal cord injury’s experiences of secondary health conditions and the impact these have on their wellbeing.Methods A qualitative descriptive design using semi-structured interviews was adopted. Purposive sampling was used to collect data from 17 participants with SCI who attend outpatient medical care at a tertiary rehabilitation hospital in Gauteng, South Africa. Primary data were collected from August 2018-July 2019. All interviews were transcribed verbatim and analysed using a thematic analysis approach.Results People with spinal cord injury experience a range of secondary health conditions, of which pain, bowel and bladder issues were the most common. The presence of SHCs had an impact on the psychological, physical and social wellbeing of the participants.Conclusion There is a need for prevention interventions (health education and screening) for SHCs throughout the continuum of care and at all levels of prevention. Further research on factors influencing the prevention and management of SHCs is needed.
The preventive effect of dexmedetomidine on adverse reactions induced by uterotonics in cesarean section: a meta-analysis
Authors: Author) Lingxi Kong(Former Corresponding , Shan Xuefeng , Wang Hongmei , Ren Yingying , Yang Yang , Author) Feng Qiu(New Corresponding
Published: October 2019

Background: To evaluate the preventive effect of dexmedetomidine(DEX) on adverse reactions induced by uterotonics used in cesarean section. Methods: Randomized controlled trials(RCTs) comparing dexmedetomidine with placebo on preventing the side effects of uterotonics in cesarean section were searched in PubMed, The Cochrane Library, and CNKI. Results: Fifteen articles with 1174 patients were included in this study. Compared with placebo, DEX significantly reduced the incidence of adverse drug reactions, such as nausea, vomiting, facial flushing, chest distress, hypertension and tachycardia ([OR = 0.12, 95% CI (0.09, 0.17), P < 0.00001], [OR = 0.12, 95% CI (0.09, 0.18), P < 0.00001], [OR = 0.21, 95% CI (0.16, 0.29), P < 0.00001], [OR = 0.19,95%CI (0.12,0.30), P < 0.00001], [OR=0.09, 95%CI (0.05,0.14), P < 0.00001], [OR=0.04, 95%CI (0.02,0.07), P < 0.00001]),which were induced by uterotonics used in cesarean section. Conclusion: Dexmedetomidine can prevent adverse reactions including nausea, vomiting, facial flushing, chest distress, hypertension and tachycardia caused by uterotonics used in cesarean section.
Adolescent physical activity: the role of parental social support and the level of physical activity. Social Support and Physical Activity of Parents and Adolescents.
Authors: Camargo Edina Maria de , López-Gil Jose Francisco , Piola Thiago Silva , Mota Jorge Augusto Pinto Silva , Campos Wagner de
Published: October 2019

Background: To verify the relationship between the level of moderate to vigorous physical activity of parents and that social support with the level of moderate to vigorous physical activity in adolescents. Methods: Cross-sectional study that selected 1390 (59.6% female) adolescents. The questionnaires IPAQ, QAFA and ASAFA were used. Binary logistic regression was used to test the relationship between the study variables. The direction and magnitude measurement were verified. Results: In relation to girls, the fact of receiving incentives from parents (OR=1.589 – CI95%=1.060-2.382) and having parents/legal guardians who meet the vigorous moderate physical activity recommendations (OR=2.038 – CI95%=1.424-2.918) was associated with meeting the vigorous moderate physical activity recommendations. Regarding boys, the support of parents related to transportation (OR=1.741 – CI95%=1.114- 2.719), parents who comment on physical activity (OR=0.440 – CI95%=0.266-0.729) and parents who meet the vigorous moderate physical activity recommendations (OR=2.739 – CI95%=1.700-4.14) were associated with meeting the recommendations for adolescents. Conclusions: The social support from parents increased to practice physical activity contributes to adolescents chances of achieving moderate to vigorous physical activity recommendation. Adolescents who have physically active parents (who comply moderate to vigorous physical activity recommendations) are almost twice as likely to comply with the recommendations.