bluuebunny/crossref_metadata_2025 huggingface dataset:
Iconic strategies in lexical sensory signs in Finnish Sign Language
Authors: Keränen Jarkko
Published: November 2021

Iconic strategies—methods of making iconic forms—have been mostly considered in terms of concrete semantic fields such as actions and objects. In this article, I investigate iconic strategies in lexical sensory signs—signs that semantically relate to the five senses (sight, touch, smell, sound, and taste) and to emotions (e.g., anger)—in Finnish Sign Language. The iconic strategy types I discuss are hand-action, entity, drawing, and locating. I also discuss the indexical strategy type (e.g., finger pointing). To gain as rich and broad a view as possible, the mixed methods in the research consist of three components: intuition based, intersubjective, and statistical analyses. The main findings are (1) that, in order from most preferred to least preferred strategy, the hand-action, the entity, the indexical, and the drawing were found in lexical sensory signs; the locating strategy was not found at all, and (2) that the interpretation of iconic strategies is not always unambiguous and absolute. In conclusion, I reflect on methodological issues, and suggest that the concept of cross-modal iconicity and indexicality should be further studied in sign language linguistics.
Multigraded Castelnuovo–Mumford regularity via Klyachko filtrations
Authors: Miró-Roig Rosa M. , Salat-Moltó Martí
Published: November 2021

In this paper, we considerℤr{\mathbb{Z}^{r}}-graded modules on theCl⁡(X){\operatorname{Cl}(X)}-graded Cox ringℂ⁢[x1,…,xr]{\mathbb{C}[x_{1},\ldots,x_{r}]}of a smooth complete toric varietyX. Using the theory of Klyachko filtrations in the reflexive case, we construct a collection of lattice polytopes codifying the multigraded Hilbert function of the module. We apply this approach to reflexiveℤs+r+2{\mathbb{Z}^{s+r+2}}-graded modules over any non-standard bigraded polynomial ringℂ⁢[x0,…,xs,y0,…,yr]\mathbb{C}[x_{0},\ldots,x_{s},\allowbreak y_{0},\ldots,y_{r}]. In this case, we give sharp bounds for the multigraded regularity index of their multigraded Hilbert function, and a method to compute their Hilbert polynomial.
High power microbial fuel cell operating at low temperature using cow dung waste
Authors: Çek Nurettin , Erensoy Ahmet , Ak Namık , Uslu Hasan
Published: November 2021

Moving towards green technology, alternatives to current detrimental, unsustainable, and expensive energy applications for eco-friendly energy are attracting great attention. Resource recycling and the convenient treatment of animal waste to diminish its nature impact are recently momentous subjects. Microbial fuel cells used cow waste have remarkable potential in electrical energy generation for clean, renewable and sustainable operation. In this study, double-chambered MFC was manufactured using cow manure as raw material at the anode chamber, graphite as the anode and cathode electrodes, fountain water in the cathode chamber, and proton exchange membrane. Because bacteria a catalytic reaction for the latent chemical energy of the cow manure was effectuated as a result of this, MFCs produced electricity. Electricity production performance of this MFC at low temperature (0–10 °C) conditions was examined. This MFC produced a maximum of 204.9 ± 0.1 mV open circuit voltage and 57.387 mW/m2 power density under low temperature conditions. In particular, the sustainability and applicability of MFCs have been increased thanks to this operation done at low temperatures (0–10 °C).
Dynamics investigation on methane hydrate formation process with combined promotion methods
Authors: Wei Yuanxia , Bai Jing , Xu Junhao , Zhang Chaoyue , Xie Gengbiao , Li Pan , Chang Chun
Published: November 2021

Rapid generation of natural gas hydrates is the basis for the application of hydrate storage and transportation. In this work, the kinetic parameters of methane hydrate formation (gas consumption, gas consumption rate constant and reaction space velocity) both in the liquid continuous impinging stream (LIS) system and sodium dodecyl sulfate (SDS) + water and LIS combination system were investigated in a liquid-continuous impinging stream reactor. The gas consumption rate constant was 3.40 × 10−8 mol2 s−1 J−1 without the impinging stream, while it increased with the increase of impinging strength and reached the maximum value of 3.68 × 10−8 mol2 s−1 J−1 when the impinging strength was 0.21. In the SDS + water and LIS combination system, when the SDS concentration was 600 mg/L, the maximum gas consumption rate constant was 3.99 × 10−8 mol2 s−1 J−1 without the impinging stream, while it reached the maximum value of 4.61 × 10−8 mol2 s−1 J−1 when the impinging strength was 0.38. The results showed that the impinging stream can effectively promote the formation rate of methane hydrate, and single mechanical promotion was better than non-promoting mode but combination promotion methods was better than single mechanical promotion.
The vehicle routing problem in the dairy sector: a case study
Authors: Rinaldi Marta , Bottani Eleonora , Solari Federico , Montanari Roberto
Published: November 2021

The vehicle routing problem is one of the most studied NP-hard combinatorial problem. In the food sector, the complexity of the issue grows because of the presence of strict constraints. Taking into account the variability and the restrictions typical of the dairy sector, the aim of this paper is to provide a practical tool for solving the milk collection problem in real scenarios. A heuristic approach has been proposed to determine a feasible solution for a real-life problem, including capacity and time constraints. Two different applications of the Nearest Neighbor algorithm have been modelled and compared with the current system. Different tests have been implemented for evaluating the suitability of the outcomes. Results show that the greedy approach allows for involving less vehicles and reducing the travel time. Moreover, the tool has been proved to be flexible, able to solve routing problems with stochastic times and high supply variability.
Terminology as a source of difficulty in translating international legal discourses: an empirical cross-genre study
Authors: Prieto Ramos Fernando , Cerutti Giorgina
Published: November 2021

Despite the persistent focus on terminology in legal translation studies, to date, no large-scale research has empirically explored the difficulty of terminology in translating legal genres. Approaches to translation difficulty in translation studies more broadly remain limited in scope. To fill this gap, a study was conducted to measure the difficulty associated with the translation of legal terminology and phraseology, as well as with terminology of other domains, in the LETRINT 1+ corpus, including nine representative genres of three institutional settings (the European Union, the United Nations and the World Trade Organization). For comparative purposes, four levels of translation difficulty were assigned to multiple terminological features by a group of specialized translators through a consensus-building process of annotation based on the cognitive effort estimated for translation decision-making. The difficulty scores obtained confirm the correlation between legal singularity and higher translation difficulty, as well as the connection of more commonly used legal terms and phrasemes, and core economic terms, with lower difficulty levels. The findings also provide evidence of the prominence of non-legal specialized terminology in institutional legal discourses, and the aggregate terminological difficulty levels of each genre examined, which can be particularly useful for informing translation quality assurance, project management and translator training.
Inertial accelerated algorithms for solving split feasibility with multiple output sets in Hilbert spaces
Authors: Okeke Chibueze C. , Jolaoso Lateef O. , Shehu Yekini
Published: November 2021

In this paper, we propose two inertial accelerated algorithms which do not require prior knowledge of operator norm for solving split feasibility problem with multiple output sets in real Hilbert spaces. We prove weak and strong convergence results for approximating the solution of the considered problem under certain mild conditions. We also give some numerical examples to demonstrate the performance and efficiency of our proposed algorithms over some existing related algorithms in the literature.
Artificial neural network for improving the estimation of weighted mean temperature in Egypt
Authors: Abdelfatah Mohamed Amin
Published: November 2021

One of the most important parameters in meteorological data is the Precipitable Water Vapor (PWV). It can be measured by radiosonde stations (RS), but the fact is that RS are not available in all times. Therefore, GNSS satellite signals are considered an accurate function to compute it within a conversation factor. The conversation factor depends on the weighted mean temperature (

T

m

{T_{m}}

) which is non-measurable.

In this research, a new idea to estimate

T

m

{T_{m}}

is provided, which can potentially contribute to the GNSS meteorology. The

T

m

{T_{m}}

was designed, including six RS, over one year in Egypt as input parameters. The machine learning (ML) model has been utilized in the design (IBM SPSS Statistics 25 package). The new model needs to collect the day of year (DOY), site location information and surface temperature to predict the

T

m

{T_{m}}

. The results of ML model and four other empirical models (Bevis et al., Wayan and Iskanda, Yao and Elhaty et al. models) are compared. The validation work is carried out, using the radiosonde data, and results indicate that the new

T

m

{T_{m}}

model can achieve the best performance with RMS of 1.7 K.
Construction of 3D model of knee joint motion based on MRI image registration
Authors: Zhang Lei , Lai Zheng Wen , Shah Mohd Asif
Published: November 2021

There is a growing demand for information and computational technology for surgeons help with surgical planning as well as prosthetics design. The two-dimensional images are registered to the three-dimensional (3D) model for high efficiency. To reconstruct the 3D model of knee joint including bone structure and main soft tissue structure, the evaluation and analysis of sports injury and rehabilitation treatment are detailed in this study. Mimics 10.0 was used to reconstruct the bone structure, ligament, and meniscus according to the pulse diffusion-weighted imaging sequence (PDWI) and stir sequences of magnetic resonance imaging (MRI). Excluding congenital malformations and diseases of the skeletal muscle system, MRI scanning was performed on bilateral knee joints. Proton weighted sequence (PDWI sequence) and stir pulse sequence were selected for MRI. The models were imported into Geomagic Studio 11 software for refinement and modification, and 3D registration of bone structure and main soft tissue structure was performed to construct a digital model of knee joint bone structure and accessory cartilage and ligament structure. The 3D knee joint model including bone, meniscus, and collateral ligament was established. Reconstruction and image registration based on mimics and Geomagic Studio can build a 3D model of knee joint with satisfactory morphology, which can meet the requirements of teaching, motion simulation, and biomechanical analysis.
An unusual presentation of primary adrenal insufficiency with new onset type 1 diabetes: case report and review of the literature
Authors: Graf Shelby , Poeppelman Rachel Stork , McVean Jennifer , Rayannavar Arpana , Sunni Muna
Published: November 2021

Objectives

To describe an atypical presentation of primary adrenal insufficiency in conjunction with new onset type 1 diabetes.

Case presentation

Here, we describe a case of new-onset type 1 diabetes (T1D) presenting simultaneously with an unusual presentation of primary adrenal insufficiency in a previously healthy 16-year-old. He was admitted for a typical presentation of diabetic ketoacidosis, but with extreme hyponatremia. An extensive workup revealed a low aldosterone level, appropriate cortisol level, and positive 21-hydroxylase antibodies. While the phenomenon of multiple autoimmune conditions developing in the same patient is well-described, this particular case has several atypical aspects. Our patient’s case highlights the danger of relying on random serum cortisol in the setting of acute illness to rule out adrenal insufficiency.

Conclusions

Adrenal insufficiency can present as isolated hypoaldosteronism without hypocortisolemia and can manifest as severe hyponatremia in the context of diabetic ketoacidosis. Workup for an unusual presentation of T1D should include a 21-hydroxylase antibody, as well as thyroid and celiac disease studies.
Ending diagnostic odyssey using clinical whole-exome sequencing (CWES)
Authors: Lam Ching-Wan
Published: November 2021

Objectives

Most rare diseases are genetic diseases. Due to the diversity of rare diseases and the high likelihood of patients with rare diseases to be undiagnosed or misdiagnosed, it is not unusual that these patients undergo a long diagnostic odyssey before they receive a definitive diagnosis. This situation presents a clear need to set up a dedicated clinical service to end the diagnostic odyssey of patients with rare diseases.

Methods

Therefore, in 2014, we started an Undiagnosed Diseases Program in Hong Kong with the aim of ending the diagnostic odyssey of patients and families with rare diseases by clinical whole-exome sequencing (CWES), who have not received a definitive diagnosis after extensive investigation.

Results

In this program, we have shown that genetic diseases diagnosed by CWES were different from that using traditional approaches indicating that CWES is an essential tool to diagnose rare diseases and ending diagnostic odysseys. In addition, we identified several novel genes responsible for monogenic diseases. These include the TOP2B gene for autism spectrum disorder, the DTYMK gene for severe cerebral atrophy, the KIF13A gene for a new mosaic ectodermal syndrome associated with hypomelanosis of Ito, and the CDC25B gene for a new syndrome of cardiomyopathy and endocrinopathy.

Conclusions

With the incorporation of CWES in an Undiagnosed Diseases Program, we have ended diagnostic odysseys of patients with rare diseases in Hong Kong in the past 7 years. In this program, we have shown that CWES is an essential tool to end diagnostic odysseys. With the declining cost of next-generation sequencers and reagents, CWES set-ups are now affordable for clinical laboratories. Indeed, owing to the increasing availability of CWES and treatment modalities for rare diseases, precedence can be given to both common and rare medical conditions.
Simon Szántó, Nineteenth Century Viennese Writer and Educator: A Study on Integration, Particularism, and the Ideal of Bildung
Authors: Yanovsky Sara Olga Melinda
Published: November 2021

Simon Szántó is known as one of the founders of the Jewish press in Vienna, the editor and main author of the Jewish periodical Die Neuzeit, and an influential educator during the high point of Austrian liberalism between the 1860s and the early 1880s. His enormously rich literary legacy covers issues such as the integration of Jews into the Austrian-Hungarian society, religious reform, gender roles, and particularly education. Szántó’s writings offer a unique opportunity to look at the Viennese liberal period of the second half of the nineteenth century and its challenges through the eyes of a mostly overlooked, but highly significant and influential actor of the time. This article will first introduce Simon Szántó’s cultural and educational background that impacted his ideals and his activities, and go on to discuss one of his main concerns, namely Jewish education. Religious education, confessional schooling, and Jewish upbringing at home bore the burden of responsibility for shaping Austrian Jewish women and men. These Jews were to be integrated in an Austrian culture, while at the same time taught to retain a strong Jewish particularity. Szántó aimed to unite this dichotomous reality through the realization of his ideals of Jewish Bildung.
Crystal structure of 1-(2-methylphenyl)-2-(2-methylbenzo[b]thienyl)-3,3,4,4,5,5-hexafluorocyclopent-ene, C21H14F6S
Authors: Jiang Duohua
Published: November 2021

C21H14F6S, monclinic, P21/n (no. 14), a = 9.9344(11) Å, b = 16.7106(18) Å, c = 11.6207(13) Å, β = 101.0080(10)°, V = 1893.7(4) Å3, Z = 4, R

gt
(F) = 0.0491, wR

ref
(F
2) = 0.1541, T = 296(2) K.
The Phenomena La Hoguette and Limburg – Technological Aspects
Authors: Kirschneck Erich
Published: November 2021

La Hoguette and Limburg pottery and the role their producers played in the Neolithization of western Central Europe are still a matter of debate. These styles exist in parallel to Linearbandkeramik (LBK) but are different from LBK pottery and here called Non-LBK wares. The various Non-LBK styles are mainly defined based on decoration, but this does not coincide with important technological features. Therefore, an technological approach including the parameters of temper, vessel morphology, and firing methods was used for an alternative classification and to trace knowledge transmission networks. It is suggested that several technologically distinguishable Non-LBK pottery traditions of different geographical origins existed contemporaneously in western Central Europe. While the early mineral- and organic-tempered ware shows some similarities with the Earliest and Early LBK, the widespread early bone-tempered pottery with its uniform design cannot be traced back to either Cardial or LBK pottery. This is probably the oldest pottery in western Central Europe. This means that here pottery emerged first as a tradition outside both the LBK and Cardial cultures. Increasing interaction between producers of various Non-LBK wares and LBK pottery makers can then be traced over several centuries. All styles are shown to be diverse and dynamic and to be undergoing substantial internal development. The persistent mutual influencing is a key for understanding the development of Non-LBK pottery, as well as for innovations within LBK ceramic production. Here, a hypothesis is proposed that the makers of Non-LBK wares may be hunter-gatherers, although this cannot currently be proven.
The Subsistence Strategy of Linear Pottery Culture in Moravia (Czech Republic): Current State of Knowledge
Authors: Čerevková Alžběta
Published: November 2021

The main goal of this article is to present an overview of current knowledge about the subsistence strategy of Linear Pottery culture (LBK) in Moravia, Czech Republic. The main aspect of the subsistence strategy mentioned here will be the issue of dietary. Early Neolithic sites that in some way contributed to the knowledge about the dietary character (both meat and plant food) will be presented here. On this occasion, a case study of the Žádovice site, which belongs to the most recently analyzed settlements, will be presented. In addition, the methods used in the subsistence strategy of LBK in Moravia will be mentioned. The existing knowledge will be included in a broader settlement context and will be compared with each other. For the time being, it seems that in terms of the species spectrum of farmed animals, the area of Moravia does not differ from the situation known from Central Europe. Certain geographical differences are possible in Moravia, but this hypothesis must be verified in the future, depending on the expansion of the database. The study thus represents a springboard for further research in this area.
Danish cult houses in north-western Germany? Rethinking the Funnel Beaker buildings of Flögeln and Hainmühlen, District of Cuxhaven
Authors: Mennenga Moritz
Published: November 2021

Two features recorded in the 1960s and 1980s in the course of excavations at Flögeln and Hainmühlen, both District of Cuxhaven, in the northern Elbe-Weser triangle, have since been repeatedly discussed in connection with cult houses from Denmark. Parts of these sites, finds and features have only been published in rudimentary form and have so far not been subject of comparative analysis. For some aspects, the information has been passed down orally for decades and has eventually found its way into the literature. In order to improve the record, the two features are presented here, followed by a comparison with similar features from the wider area of the Funnel Beaker Culture.
Einfluss COVID-19-bedingter Maßnahmen auf das touristische Buchungsverhalten am Beispiel von Flugpauschalreisen
Authors: Wegener Kerstin , Scheiber Niclas , Wehner Manuel , Holst Christian
Published: November 2021

Die COVID-19-Pandemie beeinträchtigt den Tourismus weltweit, jedoch zeigen beliebte Urlaubsregionen bei Betrachtung der realen Buchungen für das Jahr 2020 sehr heterogene Abweichungsmuster im Vergleich zum Vorjahr. In diesem Zusammenhang ist unklar, ob und welche Maßnahmen zur Eindämmung der Pandemie das heterogene Buchungsverhalten erklären. Im vorliegenden Artikel werden tourismusrelevante Maßnahmen identifiziert und anhand von Flugpauschalreisebuchungen im deutschen Quellmarkt für Reisen zwischen Mai und Oktober 2020 untersucht. Die Analyse eines umfassenden Primärdatensatzes mittels Fixed-Effects-Modellierung zeigt, dass verschiedene, vom Quellland sowie vom Zielland ausgehende Maßnahmen das Buchungsverhalten in unterschiedlicher Effektstärke signifikant beeinflussen. Darunter fallen insbesondere Reisewarnungen und Quarantäneverordnungen für Rückkehrer.
Reisen in der eigenen Stadt: Stadt(teil)tourismus während der Corona-Pandemie
Authors: Stoltenberg Luise , Stors Natalie , Frisch Thomas
Published: November 2021

Die COVID-19-Pandemie hat den noch im Jahr 2019 boomenden Stadttourismus stark getroffen, ihn jedoch keinesfalls zum Erliegen gebracht. In unserem Beitrag plädieren wir dafür, die Entwicklungen zwischen März 2020 und September 2021 als (temporäre) Transformation innerhalb des urbanen Tourismus zu verstehen. Um dieses Argument zu untermauern, beleuchten wir die drei Dimensionen unserer Konzeption von New Urban Tourism (Stors et al., 2019) im Kontext der Pandemie: Wir zeigen, dass die (1) Faszination für das Alltägliche, die (2) Begegnungen und Erschließungen neuer Orte des Zusammentreffens sowie die (3) Ko-Produktion des Städtischen auch im Kontext strikter Reiseverbote und veränderter Mobilitäten Bestand haben. Sie werden zwar von anderen Stadtnutzer*innen, Zuschreibungen und Praktiken geprägt, ändern aber nichts daran, dass Tourismus auch während einer Pandemie der Stadt inhärent ist.
Auswirkungen der COVID-19-Pandemie auf die deutschsprachige Tourismushochschullandschaft – aktuelle Einschätzungen und zukünftige Perspektiven
Authors: Hörtnagl-Pozzo Tanja , Klein Anna , Pillmayer Markus , Schmude Jürgen
Published: November 2021

Die COVID-19-Pandemie betrifft nicht nur viele Segmente der Wirtschaft und dort insbesondere die Freizeit- und Tourismuswirtschaft, sondern auch den Ausbildungssektor, d. h. Schulen, Hochschulen und Universitäten. Insofern ist die akademische Tourismusausbildung doppelt betroffen: einerseits sind Studiengänge in der bisherigen Form nicht mehr durchführbar und erfordern neue Lehrformate und -konzepte seitens der Lehrenden. Andererseits zeigen sich zunehmend Herausforderungen für den akademischen Nachwuchs, Arbeitsplätze nach Abschluss des Studiums und/oder (studiumsbegleitende) Praktikumsplätze in der Freizeit- und Tourismuswirtschaft zu finden. Der vorliegende Projektbericht widmet sich der Perspektive der Lehrenden und analysiert die Auswirkungen der COVID-19-Pandemie auf die deutschsprachige Tourismushochschul- und Universitätslandschaft.
A New Interpretation of the Opening Lines of the Assur Letters
Authors: Waal Willemijn
Published: November 2021

In this paper a new interpretation of the hatura-clauses in the Hieroglyphic Luwian Assur letters will be presented. First of all, it will be argued that the Hieroglyphic Luwian lexeme hatura-, which is usually connected to the Hittite verb ḫatrae- ‘to send’, ‘to write’ and translated as ‘letter’, is in fact related to the Hittite word ḫattuli- and Cuneiform Luwian ḫattulaḫid-, meaning ‘health’,‘wellbeing’. Secondly, the article will suggest that the Hieroglyphic Luwian word api, which is usually translated as ‘back’, or ‘again’, primarily functions as a discourse marker. Lastly, it will be proposed that the Hieroglyphic Luwian word for ‘letter’ or ‘message’ is (*205)atun(i)-. These new interpretations yield a better understanding of the opening lines of the Assur-letters and elucidate some other opaque passages of this intriguing correspondence.1
ACT001 reverses resistance of prolactinomas via AMPK-mediated EGR1 and mTOR pathways
Authors: Zhu Junhao , Tang Chao , Cong Zixiang , Yuan Feng , Cai Xiangming , Yang Jin , Ma Chiyuan
Published: November 2021

Dopamine agonist (DA) is the first choice for the treatment of prolactinomas, and drug resistance is unavoidable during treatment due to the heterogeneity of tumors. The two prolactinoma cell lines (GH3 cells and MMQ cells) were found to have different sensitivity and responding modes to the cabergoline (CAB) and bromocriptine (BRC). In this research, we disclosed the capability of ACT001, a derivative of parthenolide analogs, to activate AMPK by increasing the intracellular reactive oxygen species (ROS) level and AMP/ATP ratio to reverse DA resistance through dual pathways in prolactinoma cells. The results indicated that ACT001 could reverse the CAB resistance in GH3 cells by inhibiting the mTOR signaling pathway, inducing cell death through autophagy, and reverse the BRC resistance in MMQ cells by activating the EGR1 signaling pathway, inducing cell death through apoptosis. Our results suggested that ACT001 is a promising therapeutic compound for treating DA-resistant prolactinomas.
La andante escudería de don Pedro Calderón de la Barca
Authors: Montero Reguera José
Published: November 2021

Se estudia aquí un detalle mínimo, una expresión y algunos de sus derivados, que ofrecen un aspecto más del intenso eco que Cervantes, sobre todo el Quijote, tiene en el teatro de Calderón; ayuda, por una parte, a refrendar y comprender el modo con el que se recibió el libro del alcalaíno: para hacer reír, con sentido cómico. De otra parte ofrece un pequeño corpus de cómo Calderón encuentra en la literatura cervantina elementos diversos que contribuyen a enriquecer la parte cómica de sus comedias, a potenciarla, en todo caso. En otras palabras: lo que Calderón usa en su teatro procedente de Cervantes va generalmente unido a lo cómico.
Estrategias del relato de viajes en Juan Ruiz y el marqués de Santillana
Authors: Pérez Priego Miguel Ángel
Published: November 2021

Juan Ruiz, arcipreste de Hita, e Íñigo López de Mendoza, marqués de Santillana, aun en tiempos distintos, residieron en tierras de la cuenca alta del río Manzanares y viajaron por las sierras de Guadarrama y del norte de Madrid. Experiencias vividas en aquellos lugares inspiraron a ambos un buen número de composiciones de alta calidad poética. Examinándolas ahora en su conjunto, podemos descubrir en ellas recursos y estrategias característicos del relato de viajes.
Alphonso Hordognez «versus» Alonso Ordóñez.
Authors: Canet Vallés José Luis
Published: November 2021

En este artículo reviso la personalidad de Alphonso Hordognez, traductor de la Celestina o Tragicomedia de Calisto y Melibea al italiano en 1505 y publicada en Roma en 1506, diferenciándolo del profesor homónimo de Oratoria del Estudio General de Valencia.
Utopía en el «Quijote»: el discurso de la Edad de Oro
Authors: Albaladejo Tomás
Published: November 2021

En este artículo me ocupo del discurso de don Quijote sobre la Edad de Oro. Se estudia el discurso como un discurso ficticio dentro de una obra ficcional. La utopía contenida en el discurso es explicada como un elemento central del Quijote de Cervantes y el discurso es considerado como un eje activo y dinámico de esta obra. La oposición que hay en el discurso entre el tiempo presente y el tiempo pasado es vista a la vez como estructura social y cultural no solo del discurso, sino también de toda la obra por la activación de la analogía como fundamento de la construcción literaria del Quijote. Las perspectivas y los instrumentos que ofrece la Retórica Cultural se emplean para elucidar la composición del discurso y su papel en la totalidad del texto en el que está inserto. La conciencia de la importancia de las voces de los personajes en el Quijote permite centrarse en el discurso como uno de los principales resultados de la función de las voces en la novela en la construcción del protagonista y como representación de la sociedad. Por ello el discurso de don Quijote sobre la Edad de Oro es un componente imprescindible de la obra.
Los engaños a don Quijote. Tensión de líneas narrativas
Authors: Stoopen Galán María
Published: November 2021

A partir del primer capítulo, el universo diegético del Quijote se construye de dos líneas narrativas básicas que, a lo largo de la historia, mantienen intermitentemente una tensión entre sí: la doméstica —formada por los personajes que comparten la cotidianidad con el hidalgo— y la caballeresca —instituida por el mismo hidalgo convertido en caballero andante—. A lo largo de la historia, en las dos partes del Quijote, los personajes de la línea doméstica intentarán reincorporar al hidalgo a la domesticidad, para ellos promesa de cordura, y utilizarán distintos métodos para lograrlo. Aquí me ocuparé de analizar en la primera parte esas estrategias, así como de la tensión narrativa que crean y del éxito o fracaso que consiguen.
La belleza de las feas: releyendo el episodio romado del «Persiles» a la luz de «La española inglesa»
Authors: Fine Ruth
Published: November 2021

El presente trabajo analiza la relación especular identificable entre dos episodios presentes en La española inglesa y en el Persiles respectivamente: el envenenamiento de las heroínas, cuyo resultado es la pérdida de la belleza y la casi muerte de aquéllas. Postulo que ambas representaciones cervantinas de una fealdad transitoria configuran un juego de paralelismos e inversiones especulares, el cual constituye un llamado a la reflexión acerca de las paradojas de la representación de la dupla belleza/fealdad en estas novelas y más allá de ellas. Se sugiere también concisamente que dichos episodios vehiculizan proyecciones de orden meta-poético, respondiendo en sus modalidades a la estética que denomino como poética del cruce.
Notas para un librillo de memoria cervantino
Authors: Navarro Durán Rosa
Published: November 2021

El Coloquio de las damas (traducción de Fernán Juárez de la 3.ª jornada del Ragionamento de Aretino, 1547), el Honesto y agradable entretenimiento de damas y galanes de Giovan Francesco Straparola, traducido por Francisco Truchado (1.ª parte 1578, 2.ª 1581), la Primera parte de las cien novelas de Giraldo Cinthio, traducida por Luis Gaytán de Vozmediano (1590) y las Noches de invierno de Antonio Eslava (1609) ofrecen motivos literarios, mínimos detalles, que son pruebas de la lectura de esas obras por Miguel de Cervantes porque él les dio nueva vida en las suyas. Están reunidos en este librillo de memoria imaginario junto a la recreación cervantina.
Lope de Vega según los iniciadores científicos de la historiografía literaria española (1700-1851)
Authors: Cañas Murillo Jesús
Published: November 2021

En este artículo se investiga sobre la visión que los primeros historiadores científicos de la literatura española transmiten a la historiografía y a la crítica de épocas posteriores a la suya, sobre la figura y la producción escrita de Félix Lope de Vega Carpio, el llamado, desde el momento en que le tocó vivir, «Monstruo de la Naturaleza» y «Fénix de los Ingenios». Se muestran las semejanzas y diferencias existentes en unos y otros, en sus obras dedicadas a trabajar sobre esos asuntos. Se han utilizado treinta y seis volúmenes que sirven como testimonio de las ideas aportadas, las opiniones y juicios críticos manifestados y las noticias recogidas sobre estos asuntos. Con ello hemos querido poner de manifiesto cuáles han sido las aportaciones legadas a la posteridad por los primeros historiadores científicos de la literatura española que publican sus trabajos en la Ilustración y en la primera mitad del siglo XIX.

Palabras clave: Historiografía literaria. Siglos XVIII y XIX españoles. Biografía y producción literaria. Lope de Vega.
El ovillejo en la poesía dramática de Calderón
Authors: Antonucci Fausta
Published: November 2021

Se estudia la presencia del ovillejo en seis obras dramáticas de Calderón (Las tres justicias en una, La fiera, el rayo y la piedra, Darlo todo y no dar nada, El golfo de las sirenas, Eco y Narciso, Fieras afemina Amor). Se analizan sus características métricas y dialógicas, subrayando cómo va evolucionando con el transcurso de los años y en razón del género dramático de la pieza en que se engloba.
Cautiverios contemporáneso de Primo Levi a su sombra en España: Montserrat Roig y Jorge Semprún
Authors: Rubio Fanny
Published: November 2021

Tanto los relatos de Levi a partir de Si esto es un hombre, relativos a su estancia en el campo de concentración nazi de Auschwitz como las crónicas de los presos y presas de Ravensbrück tratados por Montserrat Roig en Noche y niebla: Los catalanes en los campos nazis, y las escenas relatadas por Jorge Semprún en La escritura o la vida (1995) y Viviré con su nombre, morirá con el mío (2001), acerca de sus vivencias en el campo de concentración de Buchenwald, nacen siempre de una fecha y un lugar en la historia vivida que no se borrará nunca de la mente de los protagonistas. De manera enigmática, los tres relatos, aparentemente independientes y separados uno de los otros, se van a entrelazar.
Hepatoprotective and Antifibrotic Effects of Indonesian Propolis
Authors: Prasetyo Diding Heri , Sarsono Sarsono , Nurwati Ida , Putranto Prihandjojo Andri , Martini Martini , Prasetyo Nabila Aushaf
Published: November 2021

Liver cirrhosis is the irreversible stage in liver damage process which occurs after liver fibrosis due to necro-inflammatory activities and liver fibrosis. Therefore, inhibition of liver inflammation and fibrosis is very important to prevent liver cirrhosis. This study aimed to analyze the effect of ethanol extract of propolis (EEP) from mount Lawu, Indonesia to prevent liver damage and fibrosis progression in mice with hepatic cirrhosis. This study was performed during the period of June 2018 to May 2019 on a sample of 32 male Balb/C mice divided into control group (P1), induction of carbon tetrachloride (CCl4 ) group (P2), induction of 50 mg/BW CCl4 + EEP group (P3), and (induction of 100 mg/KgBW CCl4 + EEP (P4) with each group consisted of eight mice. The CCl4 in olive oil was administered intraperitoneally three times a week for six weeks. Mean differences between group was determined using ANOVA test with a significance level of 0.05. The induction of CCl4 increased liver cell damage and serum alanin aminotransferase (ALT) level. However, the addition of EEP significantly (p<0.001) reduced liver cell damage as seen in P3 (54.38±4.17 per 100 liver cells) and P4 (37.13±4.36 per 100 liver cells) groups and serum alanin aminotransferase (ALT) as seen in P3 (291.19±113.92 U/L) and P4 (229.38±73.45 U/L) groups. The APRI scores were also reduced after EEP as seen in P3 (0.738±0.292) and P4 (0.513±0.253) groups. Thus, EEP isolates from Gunung Lawu can reduce liver cell damage and fibrosis in mice model of hepatic cirrhosis.
Instituciones políticas y análisis comparativo: una lectura del consenso ortodoxo en la ciencia política contemporánea
Authors: Armelino Martin , Cunial Santiago
Published: November 2021

Desde sus orígenes, la ciencia política estudia las instituciones de gobierno y la forma como se produce y distribuye el poder en una sociedad; esto lo hace de manera comparada. El artículo se propone examinar el vínculo no necesario, pero muy influyente, entre las instituciones políticas y el análisis comparativo. Su consolidación resultó del cambio que produjo en la ciencia política la irrupción del conductismo y la teoría de la elección racional, y sentó las bases para renovar el estudio de las instituciones políticas y privilegiar la política comparada como estrategia metodológica. El artículo argumenta que la reconfiguración del vínculo entre instituciones políticas y política comparada, a partir de las últimas décadas del siglo XX, ha establecido una suerte de consenso ortodoxo en la ciencia política, que supone un modelo de ciencia empírica hipotético-deductiva y una estrategia metodológica comparativa aplicada a este objeto de estudio específico para la explicación politológica.
Ganuza, E. y Mendiharat, A. (2020). La democracia es posible. Sorteo cívico y deliberación para rescatar el poder de la ciudadanía. Bilbao: Consomni. 176 pp.
Authors: Yáñez Pablo Paño
Published: November 2021

En un contexto actual de diversas crisis que se manifiestan de forma articulada, el debate sobre el sistema político y la democracia se ha vuelto habitual. La agudización de esas crisis, como a la vez la capacidad de superación, innovación y creatividad para encontrar salidas a la altura de los tiempos, y las problemáticas que deben ser atendidas, muestran tanto las emergencias como la urgencia por las alternativas en el campo democrático. La modernidad tardía, la sociedad posindustrial –o como la queramos denominar– nos traen esta necesidad de conjugación de la urgencia por resolver campos cada vez más complejos y que se manifiestan más agudamente, con las capacidades de la ciudadanía y del conocimiento creativo generado para ser capaces de enfrentar los retos que se imponen.
Michael Kohlhaas, rabia y resistencia
Authors: Romo Mateo
Published: November 2021

En la condición humana convergen dos fuerzas constitutivas: la razón y las emociones. Sin embargo, a lo largo de la historia, con mayor o menor intensidad, ha prevalecido la constante de separar, cuando no subsumir, una de estas fuerzas en la otra. La balanza se ha inclinado en exceso a favor de la razón, al punto que se va por el mundo a medio andar, luego de haber confinado en el recoveco de lo “peligroso”, lo “caótico” y lo “irrazonable” la otra mitad de lo que somos: emociones y sentimientos. Una de las emociones que más se ha censurado es la rabia. Este artículo de reflexión descree de la lectura dominante, reafirma su potencial transformador y la asume como emoción política. Para hacerlo, se trazan vasos comunicantes entre la filosofía política y la literatura a partir de una interpretación del relato de Von Kleist titulado Michael Kohlhaas, buscando flexibilizar las fronteras imaginarias entre realidad y ficción.
Presidentes y gabinetes en Argentina (1862-1930): la estabilidad ministerial en la mira
Authors: Abal-Medina Juan Manuel , Eberhardt María Laura , Ariza Andrea
Published: November 2021

Este artículo revela y analiza la composición y estabilidad de los gabinetes de ministros de los presidentes argentinos desde la asunción de Bartolomé Mitre en 1862 hasta el primer golpe militar del país en 1930. El objetivo inicial es dar cuenta de los ministros que fueron designados en los diversos departamentos y su permanencia en ellos. La fuente para emplear son los libros de actas de juramentos de los miembros del gobierno de la nación argentina, pertenecientes a la Escribanía General de la Nación. Además, se analiza la estabilidad/inestabilidad de los gabinetes, medida a partir de una herramienta específica aquí propuesta, el Índice de Estabilidad de Gabinetes (IEG), que procura convertirse en un instrumento útil para aplicar a futuros análisis sobre otros períodos y regímenes presidencialistas. Finalmente, se interpretan los resultados obtenidos bajo una perspectiva politológica que a su vez articula la consideración histórica de la época.
Aproximación a la relación entre la malaria y la economía de la coca en Guaviare, Colombia, 1979-1989
Authors: Gómez-López Natalia , Knudson-Ospina Rubiela Angélica , López-Páez Myriam Consuelo
Published: November 2021

Objetivo Analizar el comportamiento de la malaria en relación con la economía de lacoca en la región del Guaviare, Colombia entre 1978 y 1989.Métodos Revisión documental retrospectiva, a través del análisis de archivos históricos, entrevistas y fuentes secundarias.Resultados Se identificaron dos periodos de crisis de la bonanza coquera o cocalera durante el tiempo de estudio, con fluctuaciones en el número de habitantes. Al analizar la relación entre las variaciones del precio de la cocaína y los casos de malaria, se encontró que hay un incremento de casos en épocas de crisis.Conclusiones El aumento de casos de malaria en la región posiblemente se deba a que las personas que estaban en las zonas rurales se desplazaron a las cabeceras urbanas, motivadas por la baja producción de la pasta de coca. Esto incrementó la concentración de población susceptible y, por tanto, el aumento de casos, o probablemente existió un aumento en el registro de la enfermedad.
Association Between Subjects with Newly Diagnosed Rheumatoid Arthritis and Dental Caries
Authors: Sánchez-Medrano Ana Gabriela , Martínez-Gutiérrez Fidel , Martínez-Martínez Marco Ulises , Salas-Orozco Marco Felipe , Villa-García Lorena Dafnee , Patiño-Marín Nuria
Published: November 2021

Alterations in saliva, temporomandibular joint disorders, dysphagia, Sjogren's syndrome, dental caries, periodontal disease, and tooth loss have been identified in patients with Rheumatoid Arthritis. The aims of this research were 1) to study the association between newly diagnosed rheumatoid arthritis and dental caries and 2) to identify most frequent teeth with caries in study groups. A descriptive pilot study was performed. A total of 620 participants were evaluated, 29 met the selection criteria. The subjects were divided into 2 groups: 13 subjects with newly diagnosed rheumatoid arthritis and 16 subjects without rheumatoid arthritis. Salivary parameters, DMFT index, care index, FS-T index and Treatment Needs Index were evaluated in all participants. The Fisher’s Exact test and Mann-Whitney U test we used to establish the differences between groups. Low mean in all salivary parameters and a high caries frequency were observed in subjects with newly diagnosed rheumatoid arthritis compared to a control group (p<0.01). The right maxillary second premolar (n=6, 46%, p=0.0100); right mandibular second premolar (n=7,54%, p=0.0462) and left mandibular second molar (n=10,77%, p=0.0001) were the most frequent teeth with caries. Early diagnosis and early treatment of rheumatoid arthritis can improve the prognosis in most of patients. The development of new public health policies and care based on the prevention are necessary to improve the quality of patient's lives.
3D Spheroid Cell Cultures and Their Role in Bone Regeneration: a Systematic Review
Authors: Cuevas-González María Verónica , Suaste-Olmos Fernando , Cuevas-González Juan Carlos , Álvarez-Pérez Marco Antonio
Published: November 2021

Recently, the 3D spheroid cell culture application has been extensively used in the treatment of bone defects. A wide variety of methodologies have been used, which has made the comparison of results complex. Therefore, this systematic review has two aims: (i) to perform an analysis focused on the role of 3D spheroid cell culture in bone regeneration strategies; and (ii) address the main challenges in clinical application. A search of the following keywords "3D cell culture", "spheroid", and "bone regeneration" was carried out in the PubMed, Scopus, and ScienceDirect databases and limited to the years 2010-2020. Studies were included if their primary objective was the behavior of cell aggregates to formed spheroids structures by different 3D cell culture techniques focused on the regeneration of bone tissue. To address the risk of bias for in vitro studies, the United States national toxicology program tool was applied, and descriptive statistics of the data were performed, with the SPSS V.22 program. A total of 16 studies were included, which met the established criteria corresponding to in vitro and in vitro/in vivo studies; most of these studies used stem cells for the 3D cell spheroids. The most often methods used for the 3D formation were low adherence surface and rotational methods, moreover, mesenchymal stem cells were the cell line most frequently used because of their regenerative potential in the field of bone tissue engineering. Although the advances in research on the potential use of 3D spheroids in bone regeneration have made great strides, the constant innovation in cell spheroid formation methodologies means that clinical application remains in the future as strategy for 3D tissue bioprinting.
New records of Xerotyphlops vermicularis (Merrem, 1820) indicate the northernmost locality of the species in the Balkan Peninsula
Authors: Koynova Teodora , Marinova Pavlina , Stanchev Nikola , Natchev Nikolay , Jablonski Daniel
Published: November 2021

The Xerotyphlops vermicularis (Merrem, 1820) complex represents small, burrowing snakes that occur from the Balkan Peninsula to Afghanistan and generally they are mostly observed during the springtime. In the present study, we report new records of this snake (10 individuals observed) from Elenite village in coastal Bulgaria. According to current knowledge, they represent the northernmost locality of the species in the Balkan Peninsula. We expand the known distribution of X. vermicularis and help to fill information gaps.
Funções do Jornalista em ecossistema informativo digital conectado composto por máquinas sociais pré-cognitivas
Authors: Junior Walter Teixeira Lima , De Paula Fabiana Greenfield
Published: November 2021

O artigo visa discutir as competências mínimas necessárias, como dotar o profissional de jornalismo de um pensamento computacional, com o objetivo que possa atuar com relevância num ecossistema informativo composto por máquinas sociais pré-cognitivas (máquinas computacionais com viés cognitivo). Assim, a questão central deste trabalho está no debate sobre os procedimentos profissionais o jornalista deve possuir nesse novo ecossistema informativo, em função de poder exercer a sua atividade na plenitude, no campo da produção e disseminação da informação de relevância social. Para isso, argumenta a partir das premissas que compõe a Deontologia do Jornalismo, passando pelos níveis necessários de apropriação tecnológica dos profissionais da produção de informação de relevância social. Aborda o Pensamento Computacional como lógica a ser adotada para a construção mental de produtos e conteúdos jornalísticos em ambiente informativo digital conectado, visando apropriar-se com profundidade de ferramentas que possam dar valor informativo e construir narrativas apropriadas aos dispositivos de comunicação que evoluem tecnologicamente e são cada vez mais “inteligentes”.
A Folkcomunicação como processo de tradução no contexto das Epistemologias do Sul
Authors: Lopes Rafael De Figueiredo , Rodrigues Allan Soljenitsin Barreto
Published: November 2021

No artigo reflete-se sobre a teoria da Folkcomunicação como um processo de tradução de conhecimentos e experiências, no âmbito das Epistemologias do Sul, conjugando pressupostos de Luís Beltrão (comunicação) e Boaventura de Sousa Santos (sociologia). Trata-se de um texto de reflexão teórica, com o objetivo de discutir a perspectiva de um pensamento insurgente aos paradigmas hegemônicos da ciência. Desse modo, trata-se de um exercício interdisciplinar de aproximações conceituais, com base em autores da Folkcomunicação e das Ciências Sociais e Humanas, sugerindo uma alternativa para a descolonização do pensamento comunicacional.