bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemanfaatan Webinar Gratis Untuk Meningkatkan Pengetahuan Mahasiswa Politeknik Piksi Ganesha
Authors: Nuniek Dewi Pramanik  , Sulistiyono Drajat , Zuarko Adji Wilma , Korbaffo Yesus Armiro
Published: September 2022

Penulisan ini bertujuan untuk menerangkan tentang pemanfaatan webinar gratis dan peranannya dalam meningkatkan pengetahuan, wawasan, dan kompetensi mahasiswa di Politeknik Piksi Ganesha Bandung. Metode penulisan bersifat deskriptif menggambarkan fenomena pelaksanaan webinar berbagai disiplin ilmu yang telah dilakukan oleh Politeknik Piksi Ganesha serta pengaruhnya terhadap mahasiswa. Manfaat mengikuti webinar untuk mahasiswa Politeknik Piksi Ganesha diantaranya menjadikan mahasiswa lebih aktif belajar, menambah pengetahuan atau wawasan mengenai isu-isu terkini dan bahkan peluang usaha serta investasi. Keunggulan mengikuti webinar ini tidak memerlukan biaya mahal bahkan gratis, sharing informasi secara cepat, terkadang mendapatkan sertifikat dan tidak perlu hadir secara fisik. Kendala untuk menyelenggarkan webinar antara lain: koneksi internet harus stabil, kendala pemahaman Bahasa Inggris, kesulitan teknis, keterbatasan bahasa tubuh, keterlambatan sertifikat. Mahasiswa harus tetap mampu belajar secara mandiri dengan harapan untuk memperbaharui pengetahuan dan keterampilannya sehingga selalu update informasi-informasi terbaru baik tentang mata kuliah yang dipelajari maupun ilmu-ilmu yang lain.
Mental Health Literacy of OCD and OCPD in a Rural Area
Authors: McIntosh Patricia , Paulson Lauren
Published: September 2022

This study examined the mental health literacy of Obsessive Compulsive Disorder (OCD) and Obsessive Compulsive Personality Disorder (OCPD) among the rural public. 89 volunteer participants (ages 19-86) completed this study using vignette methodology and a questionnaire. Results supported the hypothesis that mental health literacy would be low, specifically for OCPD. In addition, the majority of participants viewed the disorders similarly. The findings suggest that the current understanding of OCD may not reflect the disorders true diagnostic criteria and that participants viewed both disorders similarly in regards to treatment and stigma. Implications and further recommendations are discussed.
Counselor Education Graduate Students’ Experiences with Multiple Roles and Relationships
Authors: Dickens Kristen , Cleveland Richard , Amason Lauren
Published: September 2022

Counselor Education graduate students participate in multiple roles and relationships during their programs (Dickens, Ebrahim, & Herilhy, 2016). The purpose of this quantitative investigation was to explore counselor education graduate students’ awareness of and experiences with multiple roles and relationships through the development of a self-report scale. Building on previous qualitative studies, the authors constructed a 41-item survey – the Multiple Roles, Relationships, and Responsibilities (M3R). Exploratory factor analysis was applied to data from a sampling of counseling students (n = 140) yielding an 8-factor solution accounting for approximately 63% of the variance. Implications for faculty are discussed and programmatic recommendations are offered.
Cultivating Multicultural Competency in Supervision Using an Identity Style Framework
Authors: Popejoy Erin , Shoge Kendra , Houin Cameron
Published: September 2022

Multicultural competency is a necessary component of counselor supervision. However, when ingrained and unquestioned biases tied to personal identity arise, it may feel impossible to have important conversations in a professional and safe way. The authors propose a conceptual framework that provides a navigational toolkit for these difficult conversations. A brief case example highlights a possible scenario and path to resolution.
Confidentiality in Counselor Experiential Training Groups: An Exploratory Study
Authors: Doshi Poonam , Robak Rostyslaw , Griffin Paul , Ward Alfred
Published: September 2022

This study investigated whether maintaining confidentiality influenced members’ self- disclosure and perceptions of benefitting from group experience in the context of an instructor- led experiential graduate-level training group. Participants were 31 counselors-in-training in a 60-credit master’s degree program in mental health counseling enrolled in an experiential group dynamics class. The findings indicate that maintaining confidentiality is positively associated with increased self-disclosure among group members as well as perceived benefit from the group. The implications of these findings for educators as well as practicing counselors and researchers are discussed.
Cross-Cultural Supervision: Racial/Ethnic Minority Supervisees' Perspectives
Authors: Jang Hansori , Bang Na Mi , Byrd Janice , Smith Carol
Published: September 2022

Examining the clinical supervision experiences of minority supervisees with different backgrounds than their White supervisors is essential. Weak supervisory relationships can adversely affect a supervisee’s professional competency, which in turn can negatively influence the client. This study explored the experiences of ten Racial/ethnic minority supervisees in a cross-cultural supervision setting. Using consensual qualitative research (CQR), three domains emerged: (a) cultural sensitivity, (b) cultural competency, and (c) relationship building. The outcome of this study highlights the types of training in counselor education that supervisors should consider when working with supervisees from different cultural backgrounds.
DEGREE OF APPROXIMATION OF FUNCTION OF CLASS Z w(α, γ) BY (N, p, q)C1 MEAN OF FOURIER SERIES
Authors: Sinha Santosh Kumar , Shrivastava U. K.
Published: September 2022

In this paper we have established a result on the degree of approximation of function belonging to the generalized Zygmund class z w(α, γ) by (N, p, q)C1 means of Fourier series.
RICHNESS OF A VERTEX IN A GRAPH
Authors: Rajendra R. , Reddy P. Siva Kota , Mahesh K. B. , Harshavardhana C. N.
Published: September 2022

The stress of a vertex in a graph is the number of geodesics passing through it. The status of a vertex v in a graph is the sum of the distances from v to all other vertices. We define the richness of a vertex v in a graph as the status of v minus the stress of v. The total richness of a graph is the sum of richness of all the vertices in that graph. We made some observations, compute richness of vertices in some standard graphs and obtain some interesting results.
S5-DECOMPOSITION OF KNESER GRAPHS
Authors: Sankari C. , Sangeetha R. , Arthi K.
Published: September 2022

Let A = {1, 2, 3, ..., n} and Pk(A) denotes the set of all k-element subsets of A. The Kneser graph KGn,2 has the vertex set V (KGn,2)= P2(A) and edge set E(KGn,2) = {XY |X, Y ∈ P2(A) and X ∩ Y = ∅}. A star with k edges is denoted by Sk. In this paper, we show that the graph KGn,2 can be decomposed into S5 if and only if n ≥ 7 and n ≡ 0, 1, 2, 3(mod 5).
RELATION BETWEEN GENERAL RANDIC INDEX AND ´ GENERAL SUM CONNECTIVITY INDEX
Authors: V. S. Shigehalli , Dsouza Austin Merwin
Published: September 2022

The general Randi´c index is the sum of weights of (d(u).d(v))k for every edge uv of a molecular graph G. On the other hand general Sum-Connectivity index is the sum of the weights (d(u) + d(v))k for every edge uv of G, where k is a real number and d(u) is the degree of vertex u. Both families of topological indices are well known and closely related. In fact the correlation coefficient value of these two families of indices for the trees representing the Octane Isomers vary between 0.915 to 0.998. In the recent years these families of indices have been extensively explored and studied. The major research on these indices mostly consists of the application in QSPR/QSAR analysis, computation of these indices for various molecular graphs and bounds of the indices for certain graphs, satisfying certain conditions. The main focus of this paper is a comparative study on these two families of indices for various families of graphs. We find a few algebraic relationships between general Randi´c index and general Sum-connectivity index of certain graphs.
COMMON FIXED POINT OF COMPATIBLE TYPE (K) MAPPINGS IN FUZZY METRIC SPACE
Authors: Agnihotr Swati , Dubey K. K. , Gupta V. K.
Published: September 2022

The purpose of this paper is to establish a common fixed point theorem for six self-mappings in complete fuzzy metric space, using the concept of compatibility of type (K) with another functional inequality and our result generalize the result of K. B. Manandhar and et al. [7] and other similar results in the literature.
BIANCHI TYPE V I0 STRING COSMOLOGICAL MODEL IN LYRA’S MANIFOLD
Authors: Hadole S. R. , Nimkar A. S. , Pund A. M.
Published: September 2022

A solution of field equations has been obtained for a Bianchi Type V I0 space-time with cosmic string in Lyra’s Manifold by using relation between metric coefficients and Reddy string. Also some physical and kinematic properties of the model have been examined.
PLANE STRAIN DEFORMATION WITH REPEATED CHARACTERISTICS VALUES
Authors: Madan Dinesh Kumar , Gaba Aanchal , Goyal Ritu
Published: September 2022

The objective of the present study is to derive the analytical expression for deformation field in an orthotropic elastic medium by using repeated characteristics values as a result of inclined line-load . For the procedure the method of equal characteristics value and Fourier transformation is used. To represent graphically, the elastic constants for two distinct elastic materials have been considered. To see the effect of inclination, the variations in displacements and stresses for different values of inclination i.e. at δ = 00 , 300 , 600 , 900 have been depicted graphically. It is found that normal and tangential loading influence the displacement and stresses significantly for distinct material.
ON CERTAIN IDENTITIES INVOLVING BASIC (q) HYPERGEOMETRIC SERIES
Authors: Singh Chandan Kumar , Singh Satya Prakash , Yadav Vijay
Published: September 2022

In this paper we establish certain identities by making use of Bailey’s 2Ψ2 transformation formula. Special cases of these identities have also been discussed.
ON TRANSFORMATION FORMULAS OF ORDINARY HYPERGEOMETRIC SERIES
Authors: Singh Chandan Kumar , Singh Satya Prakash , Singh Sunil
Published: September 2022

In this paper, certain transformation formulas have been established by using well-known Bailey’s transform and some known summation formulas.
A MATHEMATICAL MODEL FOR THE SEXUAL TRANSMISSION OF ZIKA VIRUS BASED ON GENDER AND SYMPTOMS
Authors: Barve Trupti , Tiwari S. K. , Porwal P. 
Published: September 2022

Zika virus is a member of Flaviviridae that also causes Japanese Encephalitis, dengue, yellow fever, and West Nile fever. General symptoms of the zika virus are low-grade fever (less than 38.5 o ), macula-papular rash, myalgia, asthenia, headache, and transient arthritis. Zika virus can cause congenital anomalies (such as microcephaly), Guillain-Barre syndrome, and other neurological and autoimmune disorders. In the present mathematical model, we observed the effect of sexual transmission on gender and symptoms based division of the infected human population. We proposed a theorem to check the local stability of disease free equilibrium state. To verify the theorem, we performed some numerical simulations. We also analyzed the global stability of disease free equilibrium state. Furthermore, we checked the effect of different sexual transmission rates on the population dynamics by calculating normalized sensitivity indices of R0. Results of the present study suggest that sexual transmission noticeably affects Zika dissemination and by controlling sexual transmission rates, we can restrict the Zika virus spread.
Fundamentos Básicos de la Medicina Veterinaria
Authors: Criollo Salinas Oscar Darwin , Chávez García Debbie Shirley , Inapanta Landa Micaela Yamilex , Pérez Caiza Maritza Katherinne , Valencia Sánchez Andrés Sebastián
Published: September 2022

FUNDAMENTOS BÁSICOS DE LA MEDICINA VETERINARIA, es un texto que se presenta de forma sencilla y de fácil lectura en la que se realiza un recorrido primordial y actualizado sobre los fundamentos, principios y alcance de la Medicina Veterinaria. Aporta de manera amigable los conocimientos esenciales de modo que estudiantes, profesionales y personas interesadas en esta área del saber puedan hacer uso del conocimiento básico en este campo de la salud.
Pelatihan Pembuatan Pizza Dan Paves Berbahan Dasar Ubi Ungu Kepada Siswa-Siswi SMK Santa Maria
Authors: Indra Febryola , Novelia Christabel Verenia
Published: September 2022

Western Cuisine merupakan istilah umum yang mengacu pada masakan Eropa dan negara-negara Barat lainnya. Di Indonesia, sudah banyak restoran yang menyajikan makanan Barat, diantaranya Pizza dan Paves. Pizza merupakan salah satu makanan yang berasal dari Italia yang berupa roti bundar dan pipih, yang dilumuri tomato concasse dan diberi berbagai macam topping diatasnya. Paves merupakan salah satu hidangan penutup berlapis yang berasal dari Brazil yang mirip dengan tiramisu. Pizza dan Paves merupakan makanan yang digemari oleh kalangan masyarakat, hanya saja memiliki kalori yang sangat tinggi. Ubi Ungu merupakan salah satu komoditas umbi-umbian yang memiliki peran dalam diversifikasi pangan yang banyak ditemui di Indonesia. Ubi ungu mempunyai beberapa manfaat yang baik untuk tubuh, terutama untuk penderita diabetes. Tujuan kegiatan Pengabdian kepada Masyarakat ini adalah: (1) Memberi pelatihan cara membuat Pizza dan Paves berbahan dasar Ubi Ungu; (2) Membangun kerjasama antara Fakultas Pariwisata Universitas Pelita Harapan dengan pihak SMK Santa Maria.
Pelatihan Aplikasi Data Kependudukan Dan Surat Menyurat Di Desa Guntung Kabupaten Batu Bara
Authors: Maulina Azmi Sri Rezki , Maulana Cecep , Amin Muhammad
Published: September 2022

Guntung merupakan salah satu desa yang ada di Kecamatan Lima Puluh Pesisir Kabupaten Batu Bara, provinsi Sumatra Utara. Desa guntung mempunyai luas wilayah 922,20 km2 dengan jumlah penduduk 358.031. Desa ini terkenal dengan mata pencaharian hasil tangkapan nelayannya. Karena lokasi desa berada  di  wilayah  pesisir pantai. Berdasarkan analisis situasi yang telah dijelaskan, dapat dirumuskan uatu masalahyangterdapatdi Desa  Guntung yaitu belum  adanya pelatihan bagi  masyarakat  untuk bisa menggunakan aplikasi  kependudukan  dan  surat menyurat. Aplikasi pengolah data kependudukan adalah perangkat lunak yang diciptakan untuk mengolah data kependudukan yang diinputkan oleh user dengan tujuan diolah menjadi informasi yang berbasis dektop. Basis data adalah kumpulan data yang saling berelasi. Surat memiliki arti sebagai sarana komunikasi sebagai penyampaian informasi yang memiliki unsur sebagai pengirim dan penerima surat. Metode pengumpulan data yang digunakan ada 3 macam, yaitu: 1. Wawancara Data yang dikumpulkan yaitu diperoleh dengan cara melalukan tanya jawab langsung kepada perrangkat desa di kantor Desa Guntung Kecamatan Lima Puluh Pesisir Kabupaten Batu Bara yang berkaitan dengan masalah yang ada di Desa Guntung. 2. Dokumentasi Pencarian data ini dilakukan dengan mengintip dan memperhatikan data yang diperoleh baik arsip dan lain-lainnya arsip yang ada di kantor Desa Guntung. 3. Studi pustaka Studi pustaka dilakukan dengan cara mempelajari teori-teori literatur dari jurnal yang berhubungan dengan objek pengabdian sebagai bahan atau dasar pemecahan masalah. Dengan  adanya  pelatihan  ini  diharapkan administrasi  desa maupun sekolah bisa lebih baik dan memudahkan untuk melakukan pengarsipan dan pencarian data
Pencegahan Tindak Pidana Penipuan Jual Beli Barang Online
Authors: Dermawan Ari , Amalia Amalia , HandokoWiwin Handoko Wiwin
Published: September 2022

Interconnection networking merupakan media penting dalam kehidupan sehari-hari dan memberikan banyak manfaat khususnya informasi   lebih   cepat   dan   mudah   di   dapatkan.   Manfaat   tersebut menjadikan internet sebagai media yang menghubungkan manusia di seluruh belahan dunia untuk berinteraksi tanpa batas. Dalam era globalisasi saat ini, banyak bermunculan model-model bisnis dengan menggunakan kecanggihan teknologi modern. Hal ini di tandai dengan berkembangnya media teknologi yang mempengaruhi aspek kehidupan manusia, khususnya dalam berteransaksi jual beli melalui online, yakni internet, peran intrnet saat ini bukan hanya aktifitas komunikasi, namun juga sebagai alat pencari informasi. Alat-alat komunikasi seperti computer, laptop, smartphone sangat memudahkan masyarakat untuk melakukan koneksi dengan internet untuk melakukan teransaksi jual beli. Transaksi e-commerce atau belanja di Toko Online memungkinkan terjadinya penipuan dalam menjualkan barang atau produk yang ditawarkan. Sehingga diperlukan suatu cara pencegahan dalam tindak pidana penipuan jual beli barang online. Penelitian ini menggunakan metode pendekatan yuridis normatif dengan menggunakan data yang diperoleh melalui penelitian kepustakaan (library research), yaitu peraturan perundang-undangan, buku-buku, makalah-makalah dan dokumen-dokumen lain yang berkaitan dengan penelitian. Permasalahan yang diambil dari penelitian ini adalah bagaimana dasar hukum dalam pidana penipuan jual beli online, bagaimana pencegahan tindak pidana penipuan jual beli online, Berdasarkan hasil pembahasan dapat disimpulkan bahwa tindakan yang dilakukan terdakwa terbukti bersalah sesuai unsur-unsur pokok dari Pasal 378 KUHP
Edukasi Peningkatan Kesehatan Masyarakat Dalam Perawatan Pasien Covid-19 di Rumah Untuk Meningkatkan Kemandirian Masyarakat
Authors: Ardilla Siregar Maya , M. Lubis Afina , Mulidan Mulidan
Published: September 2022

COVID 19 saat ini telah menjadi pandemi dan menjadi masalah kesehatan dunia khususnya di Indonesia. Jumlah kasus positif COVID 19  di Indonesia merupakan yang tertinggi di wilayah Asia. Selama beberapa bulan ke depan bangsa Indonesia akan menghadapi masalah besar disebabkan COVID 19, apabila tidak ditangani dengan tepat. Pasien dengan COVID 19 tidak hanya di rawat di rumah sakit saja, karena pasien dengan gejala ringan atau tanpa gejala atau pada pasien yang sudah berkurang gejalanya maka akan dianjurkan untuk isolasi mandiri di rumah. Oleh karena itu keluarga berperan penting dalam perawatan pasien COVID 19, agar tidak menambah parah dan tidak menularkan ke anggota keluarga lain.  Tujuan pelaksanaan pengabdian masyarakat ini adalah untuk memberikan edukasi pada ibu-ibu majelis taklim Masjid Ar Ridho terkait perawatan pasien COVID 19 di rumah. Metode yang digunakan dalam pelaksanaan pengabdian masyarakat ini adalah dengan memberikan penyuluhan melalui ceramah dan memberikan leaflet berisi materi penyuluhan di Majelis Taklim Masjid Ar Ridho Jalan Abdul Hakim Gg Masjid Ar Ridho, Tanjung Sari, Medan Selayang, Kota Medan, Sumatera Utara, 20132. Sasaran pelaksanaan kegiatan adalah ibu-ibu majelis taklim Masjid Ar Ridho.
Proses Hak Tanggungan Terintegrasi Secara Elektronik
Authors: Hamdani
Published: September 2022

Indonesia adalah negara hukum sesuai dengan yang diamanatkanoleh Pasal 1 Ayat (3) Undang-Undang Dasar Negara Republik IndonesiaTahun 1945. Indonesia memiliki banyak sekali peraturan yang mengaturberbagai macam hal demi menjamin kepastian hukum bangsanya. Hak tanggungan adalah hak jaminan yang dibebankan pada hak atas tanah sebagaimana dimaksud dalam UndangUndang Nomor 5 tahun 1960 tentang Peraturan Dasar Pokok-Pokok Agraria. Pelaksanaan pembebanan Hak Tanggungan dilakukan penyederhanaan proses dengan diterbitkannya Peraturan Menteri Agraria danTata Ruang/Kepala Badan Pertanahan Nasional Nomor 5 Tahun 2020 tentang Pelayanan Hak Tanggungan Terintegrasi Secara Elektronik. Pelayanan hak tanggungan dilaksanakan terintegrasi secara elektronik bertujuan untuk meningkatkan pelayanan Hak Tanggungan yang memenuhi asas keterbukaan, ketetapan waktu, kecepatan, kemudahan, efektifitas dan efisiensi. semula dilakukan secara manual menjadi berbasis pada sistem elektronik yang terintegrasi. Penelitian ini Merupakan penelitian empiris, yaitu jenis penelitian yang menggunakan pendekatan kualitatif dengan menggunakan data yang diperoleh melalui penelitian kepustakaan (library research), yaitu peraturan perundang-undangan, buku-buku, jurnal-jurnal dan dokumen-dokumen lain yang berkaitan dengan penelitian ini serta media elektronik (internet). Permasalahan yang diambil dari penelitian ini adalah bagaimana pelaksanaan hak tanggungan terintegrasi secara elektronik di kantor Badan Pertanahan Nasional, dan Kendala dalam  pelaksanaan hak tanggungan terintegrasi secara elektronik di kantor Badan Pertanahan Nasional.
Rancang Bangun Aplikasi Wakaf Online (SIWON) Berbasis Web Pada Badan Wakaf Al Qur’an
Authors: Gunawan Sudarsono Bernadus , Setiani Lilis , Poedji Lestari Sri
Published: September 2022

Badan Wakaf Al Qur’an (BWA) merupakan lembaga filantropi yang menyalurkan wakaf hingga ke pelosok daerah. Pemberian wakaf bersifat sukarela yang memiliki nilai jangka panjang dan manfaat yang luas bagi penerimanya. Dalam hal ini, peran wakif (sebutan bagi pemberi wakaf) merupakan salah satu wadah yang berkontribusi terhadap kesejahteraan penerima wakaf. Adanya perkembangan teknologi memudahkan wakaf untuk mendapatkan informasi, sehingga pendistribusian wakaf dapat terlaksana dengan baik dan tepat sasaran. Sehingga perlu diciptakan sistem pendistribusian wakaf yang lebih fleksibel dengan memanfaatkan teknologi yang mendukung kegiatan di bidang sosial kemanusiaan. Namun dalam proses pengelolaan wakaf masih menggunakan kertas dan dikelola dengan excel atau word. Pengelolaan wakaf seperti ini menambah beban kerja dan keterbatasan informasi bagi calon wakif. Observasi, wawancara dan desain adalah metode pemecahan masalah saat ini. Dengan dukungan model sistem Unfied Modeling Language (UML), System Development Life Cycle (SDLC) dan bahasa pemrograman PHP berbasis web serta MySql sebagai database, diharapkan SIWON dapat mengatasi keluhan yang dialami oleh perusahaan serta menjadi saran bagi pengelolaan wakaf berjangka. lebih efektif. Semua proses pada sistem yang berjalan dapat saling terintegrasi dan data wakif menjadi lebih aman.
Public health impact of hearing impairment and
disability

Authors: Kotby MN , Tawfik S , Aziz A , Taha H
Published: September 2022

This presentation of the public health impact of hearing impairment highlights the
important elements of interaction between the disability and community.
Objectives:
Retrospective study to identify the size of the problem of hearing loss, illustrating
not only the magnitude but also the serious effect of the lack ofreliable data
concerning this matter. It highlights the challenges met within a mid-economy community
regarding the handling of the impact of the disability. The Egyptian data is given as an
example of the situation in a mid-economy community.
Study design: A brief
introduction of some epidemiological factors of hearing impairment is presented
including the size of the problem in Egypt. Data of the neonatal hearing screening
program of the Audiology Unit, Ain Shams University, is presented. The impact of the
disability is then discussed in relation to the age of onset and the degree and type of
hearing loss. This is followed by the description of the nature and effect of the
disability in the different age groups. A discussion of the various factors that may
modify the capability of the community to deal with such disability follows. This
includes various economic indices with their possible limitations on the part of the
community. Such a briefing illustrates the challenges met in the rehabilitation of the
deaf and the hearing-impaired in a developing mid-economy country. The broad lines of
the management of the problem both at the prophylactic as well as the rehabilitative
levels are discussed. A final remark on recommendations and possible future development
in a developing country is presented.
Published courtesy of: Folia Phoniatr Logop.
2008; 60(2): 58-63.
Migraine associated with auditory-vestibular dysfunction

Authors: Cal R , Bahmad Jr F
Published: September 2022

The association between hearing and balance disorders with migraine is known since
the times of the ancient Greeks, when Aretaeus from Cappadocia in 131 BC, made an
accurate and detailed description of this occurrence during a migraine episode. We
present a broad review of migraine neurotological manifestations, using the most recent
publications associated with epidemiology, clinical presentation, pathophysiology,
diagnostic methods and treatment for this syndrome.
Aim: To describe the clinical
entity: ‘Migraine associated with auditoryvestibular dysfunction’, in order to help
otorhinolaryngologists and neurologists in the diagnosis and management of such
disorder.
Final Remarks: There is a strong association between neurotological
symptoms and migraine, and the auditory-vestibular dysfunction-associated migraine is
the most common cause of spontaneous episodic vertigo (non-positional). Symptoms may
vary broadly among patients, making it a diagnostic challenge to the
otorhinolaryngologist. This entity usually presents with positional or spontaneous
vertigo spells, lasting for seconds or days, associated with migraine symptoms. A better
understanding of the relationship between central vestibular mechanisms and migraine
mechanisms, besides the discovery of ionic channel disorders in some cases of migraine,
ataxia and vertigo, may lead to a better understanding of migraine pathophysiology
associated with audio-vestibular disorder.
Published courtesy of:Braz J
Otorhinolaryngol. 2008; 74(4): 606-612.
Sensorineural hearing loss in chronic suppurative otitis media with and
without cholesteatoma

Authors: De Azevedo AF , Pinto DC , De Souza NJ , Greco DB , Gonçalves DU
Published: September 2022

Sensorineural hearing loss (SNHL) related to chronic suppurative otitis media
(CSOM) was studied to clarify the involvement of cholesteatomas in this context.

Aim: to evaluate SNHL related to CSOM and its association with cholesteatomas, disease
duration and patients ages.
Methods: Retrospective analysis of 115 patients with
CSOM, with and without cholesteatoma, submitted to surgical treatment. Inclusion
criteria were active unilateral disease, normal contralateral car and age below 60
years.
Results: The average age was 26.3 years, 58 males and 57 females. The
duration of ear disease was, in average, 12.4 years. The average threshold of hearing
was 40 dB in CSOM ear and 22 dB in the normal contralateral ear (P=0.002). CSOM with
cholesteatoma occurred in 78 of 115 cases. In the abnormal ear, SNHL was seen in 15
cases, being 6 cases of profound loss, that correlated with adjusted-age (P=0.003) and
absence of cholesteatoma (P=0.01), but not with disease duration (P=0.458).

Conclusion: SNHL occurred in 13% of the patients with CSOM, and was correlated with
older age, but not with the presence of cholesteatoma or longer duration of ear
disease.
Published courtesy of.Rev Bras Otorrinolaringol (Eng Ed). 2007; 73(5):
671-674
Progress towards early detection services for infants with hearing loss in
developing countries

Authors: Olusanya Bolajoko O , Swanepoel De Wet , Chapchap Mônica J , Castillo Salvador , Habib Hamed , Mukari Siti Z , Martinez Norberto V , Lin Hung-Ching , McPherson Bradley
Published: September 2022

Background: Early detection of infants with permanent hearing loss through infant
hearing screening is recognised and routinely offered as a vital component of early
childhood care in developed countries. This article investigates the initiatives and
progress towards early detection of infants with hearing loss in developing countries
against the backdrop of the dearth of epidemiological data from this region.

Methods: A cross-sectional, descriptive study based on responses to a structured
questionnaire eliciting information on the nature and scope of early hearing detection
services; strategies for financing services; parental and professional attitudes towards
screening; and the performance of screening programmes. Responses were complemented with
relevant data from the internet and PubMed/ Medline.
Results: Pilot projects using
objective screening tests are on-going in a growing number of countries. Screening
services are provided at public/private hospitals and/or community health centres and at
no charge only in a few countries. Attitudes amongst parents and health care workers are
typically positive towards such programmes. Screening efficiency, as measured by
referral rate at discharge, was generally found to be lower than desired but several
programmes achieved other international benchmarks. Coverage is generally above 90% but
poor follow-up rates remain a challenge in some countries. The mean age of diagnosis is
usually less than six months, even for community based programmes.
Conclusion: Lack
of adequate resources by many governments may limit rapid nationwide introduction of
services for early hearing detection and intervention, but may not deter such services
altogether. Parents may be required to pay for services in some settings in line with
the existing practice where healthcare services are predominantly financed by
out-of-pocket spending rather than public funding. However, governments and their
international development partners need to complement current voluntary initiatives
through systematic scaling-up of public awareness and requisite manpower development
towards sustainable service capacities at all levels of healthcare delivery.

Published courtesy of: BMC Health Services Research 2007, 7:14-29
This article is
available from: http://www. biomedcentral.com/1472-6963/7/14
Aetiology of deafness among children at the Buguruni School for the Deaf
in Dar es Salaam, Tanzania

Authors: Minja B M
Published: September 2022

To identify the causes of deafness, 354 pupils attending the Buguruni School for
the Deaf in Dar es Salaam, Tanzania, were studied. Of these children 205 were boys and
149 were girls, a sex ratio of 1.4:1. The onset of deafness was congenital in 36 (10.2%)
and acquired in 318 (89.8%). Among the children with acquired deafness, the cause was
unknown in 77 (24.2%); meningitis in 76 (23.9%); ototoxicity in 66 (20.8%); mumps in 53
(16.7%); febrile convulsions in five (1.5%), otitis media in 28 (8.8%) and measles in 13
(4.1%). Among the children with congenital deafness, only ten (27.8%) were identified
before the age of 2 years. The findings indicate that most (75.8%) of the causes of
acquired deafness are preventable through immunization, early diagnosis and proper
treatment of ear infections and avoidance of prescription of ototoxic drugs. This
emphasizes the need for programmes aimed at improving the health services at primary
levels of health care which will in turn prevent deafness.
Published courtesy of:
Int I Pediatr Otorhinolaryngol. 1998; 42(3):225-231
Practical screening priorities for hearing impairment among children in
developing countries

Authors: Gell FM , White EM , Newell K , Mackenzie I , Smith A , Thompson S , Hatcher J
Published: September 2022

Routine screening for hearing impairment in childhood is now widespread in
industrial countries, although there is considerable controversy over the most efficient
techniques and procedures. In most developing countries, however, routine screening
programmes for hearing impairment do not currently exist. The problems involved in
implementing screening programmes in developing and industrial countries are very
different, and in selecting screening procedures for a particular population the
following factors have to be taken into consideration: the environmental test
conditions; the availability of resources for equipment and the training of testers; the
local attitudes towards disability; the level of hearing impairment that may cause
handicaps; and the major types of pathology causing hearing impairment. We suggest that
in developing countries children should be screened at school entry using a simple field
audiometer and that the external ear be inspected for the presence of a discharge. There
is an urgent need to develop reliable and simple screening procedures for infants and
young children; where possible, all children should be screened for severe or
significant hearing impairment before the age of 2 years. No screening should, however,
be implemented until appropriate follow-up services are available.
Published
courtesy of: Bull World Health Organ. 1992; 70(5):645-655
Prediction of excipient-excipient incompatibility: A latent threat to pharmaceutical product development
Authors: Hamid Junaid Ul , Gupta Sunil
Published: September 2022

The importance of pharmaceutical excipients in the creation of any dosage form is critical. These excipients are occasionally to blame for product underperformance and dosage form deterioration. Product deterioration and underperformance could be attributed to incompatibilities between drug and excipient or sometimes excipient and excipient either due to the presence of reactive impurities in the excipients or a reaction between the functional groups present on the excipients. Although the drug and excipient incompatibilities are monitored and reported, excipient-excipient incompatibilities are overlooked due to a paucity of the literature. Pharmaceutical companies used to work in a controlled environment (compatibility tests between excipients to determine the best excipients for dosage form creation) and utilize mitigation measures to suppress any incompatibilities between excipients when necessary. These tactics take time and money to implement, and they increase the cost of developing a dosage form. However, the primary goal of this review is to highlight some of the most prevalent excipient-excipient incompatibilities that can occur during dosage form development, possible incompatibility reactions, as well as a potential method for predicting excipient-excipient incompatibilities based on structural information. The structure incompatibility relationship strategy to forecast incompatibilities between diverse excipients is an idea based on the reactivity of pharmaceutical excipients, and it might be a useful tool in reducing the time, cost, and product failures during the product development due to excipient-excipient incompatibilities.
Computational screening for the identification of potent tubulin inhibitors as anticancer agents
Authors: Sharma Priyanka , Asati Vivek
Published: September 2022

Tubulin is a biological target for several multiple clinically used anticancer drugs which is responsible for chromosome segregation, cell shape maintenance, transport, motility, and organelle dispersion, among other things. For decades, anticancer medicines that target the microtubule, such as taxanes and vinca alkaloids, have formed the cornerstone of many chemotherapy regimens. However, these medicines have substantial drawbacks, prompting the development of new microtubule targeting compounds. The pyrazole ring system is a critical component of various tubulin inhibitors discovered in recent years. In the present study, a dataset of tubulin inhibitors have been downloaded from PubMed database and included for screening study by Glide module. The Lipinski rule of 5, high-throughput virtual screening, standard precision, and extra precision methodologies have been used for final screening of potent compounds against tubulin protein (PDB ID: 3E22). The docking studies of these inhibitors revealed a complementary fit in the allosteric site of Tubulin protein. Among all the selected inhibitors, Centaureldin and Chalcones MDL showed the highest docking scores of −7.76 and −6.21 kcal/mol, respectively, when compared with the cocrystal ligands of PDB-3E22. Postmolecular mechanics/generalized born surface area analysis of these potent inhibitors showed dG binding values −37.83 and −28.37 kcal/mol, respectively. On the basis of final screened compounds, we can further develop pharmacophore model and screened potential compounds against tubulin protein.
Substantiating the mechanism of Boswellic acids through molecular docking study
Authors: Sahu Chandrakant , Chawla Pooja A.
Published: September 2022

Inflammation is the first response shown by the immune system in defense to any attack by bacteria or viruses. Inflammation is responsible for contributing to half of the world’s global burden of disease. It is mainly characterized by pain (dolor), heat (calor), swelling (tumor), and redness (rubor). The inflammatory cascades are the sole reasons for many musculoskeletal disorders. These musculoskeletal disorders are prevalent throughout the world, with a ubiquitous impact leading to long-term pain and disability. They significantly affect the psychosocial status of people who have them. Boswellic acids (BA), a natural mixture isolated from oleo gum resin of Boswellia serrata comprised of four major pentacyclic triterpene acids: Beta-BA, 3-acteyl beta BA, 11-keto-beta-BA, and 3-acetyl-11-keto-beta-BA, isolated from the oleo gum resin of B. serrata is reported to be effective as anti-inflammatory, immunomodulatory, anti-tumor, anti-asthmatic and in chronic colitis. Its anti-inflammatory activity has been attributed to the inhibition of 5-lipoxygenase in a selective, enzyme-linked non-redox, and non-competitive manner. The anti-asthmatic reports on BA revealed that leukotriene and elastase enzyme inhibition might be responsible for this effect. Although BA acts through several mechanisms for its biological activities, the inhibition of leukotrienes is the primary and the most scientifically proved mechanism. This work substantiates the effect of B. serrata BAs through molecular docking study into the cavity of 5-LOX enzyme.
Numerical Analysis of the Effect of Cement Sheath Defects on Casing Damage in Heavy Oil Thermal Recovery Wells
Authors: Liu De , Chen Xuyue , Zuo Kun , Yin Siyuan , Liu Nanxiang
Published: September 2022

In the process of thermal recovery of heavy oil, casing damage caused by local defects of cement sheath is serious and caused huge economic losses to the oilfield. Nowadays, there is a relative lack of research on the mechanism of casing damage caused by cement sheath defects in heavy oil recovery wells. In this thesis, the radial and circumferential loss of cement sheath models and the loss of gas intrusion channel models are established. Using the thermal-solid coupling finite element analysis method of transient heat transfer, the effect of cement sheath failure on the temperature field and stress field of thermal recovery wells are analyzed. The study finds that when the cement sheath missing thickness ratio increases to 1/5 to 3/5 or the missing angle exceeds 30°, the casing is prone to yield failure. When the missing angle is 60°or 120°, the cement sheath is prone to secondary collapse. As the higher proportion of gas intrusion channel area and the more gas intrusion channels, the higher the maximum Mises stress of the casing and the worse the wellbore integrity. Through systematic analysis of the impact of the lack of cement sheath on the temperature field and stress field of the wellbore, it provides an important reference for the study of casing damage caused by the failure of the cement sheath.

1. INTRODUCTION

At present, the world’s heavy oil resources are quite abundant. With the declining thin oil resources and the increasing demand for energy in countries around the world, heavy oil will become the main energy source for world economic development. There are m any exploitation methods for heavy oil reservoirs, mainly steam flooding and steam huff and puff (Shi 2015). The main function of the cement sheath is to isolate the casing and the formation, prevent gas invasion and channeling, and protect the safety of casing strength and wellbore integrity (Yu 2016, Chen et al. 2016, Chen et al. 2018). In the process of thermal recovery of heavy oil, the casing and cement sheath are easily dam aged by the interaction of complex downhole conditions and various loads, failing the integrity of the wellbore and complex accidents, and in severe cases, the well will be scrapped.
Geomechanics Rock Property Uncertainty Workflow Using a Bayesian Machine Learning Framework
Authors: Ray Peng , Lui Arthur , Francom Devin , Cheng Shuxing
Published: September 2022

Geomechanical rock properties have a broad impact on drilling, completion, production, and reservoir management decisions. Accurate quantification of measurements and correctly propagating uncertainty throughout the modeling process can improve decision quality and reduce the cost of field development. Laboratory rock property tests are generally sparse. To build a mechanical earth model for the entire field, empirical correlations are used to bridge the gap between lab data and petrophysical or geophysical measurements. Empirical correlations often rely on limited core test data from one or a few fields for a specific formation. This makes applying a correlation that is developed for a specific field to other fields difficult.

A Bayesian machine learning approach is presented for modeling the rock properties. It provides a robust framework for building multivariate rock property models and evaluating uncertainties associated with the model. Core test data from many different fields with large variations of properties were used for this study. The workflow uses a hierarchical Bayesian regression, which enables the accurate learning of field-specific correlations in fields with much data and borrowing of correlation information from other fields in fields with little data.

1. INTRODUCTION

Evaluating rock strength and elastic properties is fundamental to building a mechanical earth model (MEM). Most common geomechanical rock properties used in a MEM are unconfined compressive strength (UCS), Young’s Modulus (YM), Poisson’s ratio (PR), and friction angle (FA). A MEM has broad applications in drilling, completion, and production, such as calculating safe drilling windows, establishing injection limits for CO2 storage, enhanced oil recovery, and evaluating sand production risk, etc. (Plumb, 2000 and Ray et al 2007) Therefore, having the most accurate assessment of rock properties and the associated uncertainties is vital.

Geomechanical rock properties are best characterized by direct laboratory measurements using downhole cores. However, coring can be a very expensive operation when factoring in equipment and rig costs. In most fields, cores are acquired in only a few carefully selected wells and intervals and, therefore, direct core measurements for a given field are limited. To build a MEM for the entire field, one must rely on empirical correlations using geophysical measurements, such as well logs and seismic data, and calibrate them to direct core measurements.
Influence of Trace H2S on CO2 Corrosion of Different Cr-Containing Tubing Steels
Authors: Wang Yindong , Ye Sutao , Gao Haiyang , Chen Zhitao , Wang Zhongli , Yang Junqi , Lu Lang , Wang Zhengjie , Li Yantong , Yan Wei
Published: September 2022

Corrosion of tubing steel induced by H2S and CO2 is an important risk factor for oilfield production and development. The trace amounts of H2S can induce local corrosion of X65 carbon steel, but there are few researches on the corrosion of low Cr steel. In this paper, the experimental process is designed to prepare trace H2S at 40°C to study the corrosion effect of N80 carbon steel, 1%wt Cr steel, 3%wt Cr steel and 13%wt Cr steel under CO2 environment that the partial pressure of H2S is 2 × 10−6-6 × 10−6 MPa. The results show that the N80 carbon steel has uniform corrosion behavior, and the Cr steel has different degrees of pitting corrosion characteristics. Finally, after calculating the corrosion rates of different Cr-containing tubing steels, it is found that the pitting corrosion rate of 1%wt Cr steel is more than three times that of 3%wt Cr and 13%wt Cr steels, which further indicates that trace H2S can induce serious pitting corrosion behavior of Cr steel. This discovery can help oilfield provide a theoretical basis for the optimization of the pipe materials used in the upper wellbore with a small amount of H2S, which can bring significant economic benefits.

1. INTRODUCTION

The corrosion of tubing and casing seriously restricts the production and development of major oilfields in China. In the traditional CO2 corrosion environment, the presence of H2S will slow down the corrosion process of tubing and casing. However, the CO2 environment containing the trace amounts of H2S will induce local corrosion of the tubing and casing, which has a risk of pitting corrosion and perforation (Navabzadeh et al., 2017; Yan et al., 2018).

At present, international scholars have conducted many researches on carbon steel in the CO2 corrosion environment with trace H2S. Those researches show that the corrosion of oil pipe steel is obviously inhibited when the H2S concentration of carbon steel is less than 100 ppm, thereby delaying the corrosion process of the matrix (Bruce et AL., 2004). At the same time, different partial pressure of H2S will lead to pitting corrosion and uniform corrosion of pipeline steel. When H2S pressure is lower than 8 × 10−6 MPa, pitting corrosion occurs on the surface of pipeline steel; when H2S partial is higher than 8×10−6 MPa, there will not be pitting corrosion, when H2S is not contained, no pitting corrosion occurs (Yaakob et al., 2016).
Cementing Technology with Narrow Safety Density Window Based on Wall Shear Stress Theory
Authors: Liu Zhongfei , Wang Chunsheng , Zhou Bo , Gao Haiyang , Chen Jianglin , Zhao Jun , Wang Tianbo
Published: September 2022

The geological conditions in front of Kuqa piedmont in Tarim Oilfield are extremely complex. High pressure salt water and weak layer coexist in the salt layer, fractures are developed in the target layer, and oil/gas shows are active. Therefore, the contradiction between pressure stabilization and leakage prevention in cementing is prominent. The safety density window of cementing is only about 0.03~0.10g/cm3. Based on the theory of wall shear stress, a set of narrow safe density window cementing technology suitable for Kuqa piedmont front is formed by finely evaluating leakage pressure, optimizing construction displacement and slurry rheological properties, which can effectively improve the cementation quality of cement-stone interface. From 2020 to 2021, more than 40 wells of the narrow safety density window cementing technology will be applied on site, and the cementing qualification rate will be increased by 30%. The effective isolation rate of high-pressure brine and the pass rate of negative pressure channeling test of the target layer are both 100%.At the same time, the managed pressure cementing technology was successfully applied for 7 wells, which provided effective technical support for narrow-density window cementing.

1. INTRODUCTION

The engineering geological conditions of the Tarim Kelasu tectonic belt are complex. The narrow safe density window severely restricts the implementation of techniques to improve displacement efficiency, such as increasing displacement, increasing slurry density difference, and fully circulating wells, making it difficult to guarantee cementing quality. High pressure brine (pressure coefficient 2.30-2.60 g/cm3) and weak layer (pressure bearing capacity between 2.05-2.20 g/cm3) coexist in the piedmont salt layer (Johnston, et al., 1992; Yan, et al., 2019). Fractures are developed in the target layer and the risk of gas channeling is high. In order to stabilize the gas-water layer, the drilling fluid density is forced to increase, resulting in a further narrowing of the safe density window. Some downhole casings are lost or lost, and only positive injection and reverse extrusion can be used. Although reducing the displacement can barely achieve one-time upstroke, the interface cementing quality of the cement sheath is poor, and it is easy to generate micro-annulus. At the same time, in order to safely run the casing under the salt layer to the bottom of the well, some wells use the casing without couplings. In the case that the centralizer cannot be matched, the average degree of the pipe string is only 20%. The eccentric annulus causes poor displacement geometry, and cementing displacement efficiency is more difficult to ensure displacement.