bluuebunny/crossref_metadata_2025 huggingface dataset:
Acute Declines in Renal Function during Intensive BP Lowering and Long-Term Risk of Death
Authors: Ku Elaine , Ix Joachim H. , Jamerson Kenneth , Tangri Navdeep , Lin Feng , Gassman Jennifer , Smogorzewski Miroslaw , Sarnak Mark J.
Published: July 2018

Background

During intensive BP lowering, acute declines in renal function are common, thought to be hemodynamic, and potentially reversible. We previously showed that acute declines in renal function ≥20% during intensive BP lowering were associated with higher risk of ESRD. Here, we determined whether acute declines in renal function during intensive BP lowering were associated with mortality risk among 1660 participants of the African American Study of Kidney Disease and Hypertension and the Modification of Diet in Renal Disease Trial.

Methods

We used Cox models to examine the association between percentage decline in eGFR (<5%, 5% to <20%, or ≥20%) between randomization and months 3–4 of the trials (period of therapy intensification) and death.

Results

In adjusted analyses, compared with a <5% eGFR decline in the usual BP arm (reference), a 5% to <20% eGFR decline in the intensive BP arm was associated with a survival benefit (hazard ratio [HR], 0.77; 95% confidence interval [95% CI], 0.62 to 0.96), but a 5% to <20% eGFR decline in the usual BP arm was not (HR, 1.01; 95% CI, 0.81 to 1.26; P<0.05 for the interaction between intensive and usual BP arms for mortality risk). A ≥20% eGFR decline was not associated with risk of death in the intensive BP arm (HR, 1.18; 95% CI, 0.86 to 1.62), but it was associated with a higher risk of death in the usual BP arm (HR, 1.40; 95% CI, 1.04 to 1.89) compared with the reference group.

Conclusions

Intensive BP lowering was associated with a mortality benefit only if declines in eGFR were <20%.
Avaliação da prevalência de infecção pelo Mycobacterium tuberculosis em estudantes de medicina
Authors: De Masi Flavia David João , Nassif André Thá , Sandoval Paulo Roberto Miranda , Camargo Rosana , Kamei Douglas Jun , Reich Gabriela
Published: July 2018

Justificativa e Objetivo: Estimar a prevalência da infecção pelo Mycobacterium tuberculosis em acadêmicos de medicina e fatores associados.Uma avaliação adequada incrementa as estratégias de biossegurança institucional, além de prover uma quimioprofilaxia adequada. Métodos:Estudo transversal, realizado de agosto de 2013 a julho de 2014 onde foram incluídos 62 estudantes de medicina Foi realizado teste tuberculínico e entrevista. O teste tuberculínico foi realizado através da técnica de Mantoux. A leitura do teste foi realizada pelo método palpatório, 48 a 72 horas após a injeção. Os dados coletados na entrevista foram os seguintes: período que se encontra no curso, história de atopia, história de hipersensibilidade ao PPD, histórico vacinal da BCG, vacinação de vírus vivo atenuado nas últimas 4 semanas, tuberculose prévia, exposição potencial, tempo de exposição. Resultados:30,6% dos estudantes eram reagentes. A maior prevalência de casos reagentes foi em estudantes do sexo masculino. Conclusão: A prevalência de teste tuberculínico reator forte é relativamente baixa entre os estudantes de medicina, porém relevante para a estratificação de risco desta população.
La relación sujeto-objeto en la concepción kantiana de la ciencia.
Authors: Chaves-Montero Alfonso , Gadea Aiello Walter Federico
Published: July 2018

Nuestra investigación presenta la propuesta kantiana del idealismo trascendental como una filosofía crítica mediadora entre el dogmatismo propio del racionalismo y el escepticismo generado por el empirismo sensualista. Nuestro trabajo realiza una breve presentación de las formas del juicio que conforman las distintas formas del conocimiento humano. Resulta de gran importancia el reconocer y tener en cuenta, al estudiar el pensamiento filosófico actual, la relevancia profundísima que Kant ha tenido en la historia y en el desarrollo del pensamiento contemporáneo. Kant establece una diferencia fundamental que es decisiva para la justa compresión de su pensamiento. Es la diferencia entre conocer y pensar. Dicho breve y sencillamente: no todo lo real es susceptible de ser conocido, pues conocer significa, en vigor, conocimiento científico. Ahora nos interesa analizar la naturaleza y la posibilidad del conocer: ¿cómo es posible el conocimiento?; ¿cuál es su alcance y su límite? A ello está dedicada la primera parte de la Crítica de la razón pura: la «Doctrina trascendental de los elementos». Además, vamos a presentar la compleja relación que establece Kant entre la razón en sus usos teóricos y la razón en sus usos prácticos. Se introduce un análisis comparativo entre idealismo y realismo, utilizando una metodología hermenéutica y un análisis del discurso filosófico dialéctico en términos de antítesis conceptuales. Por último, planteamos la diferencia entre teoría y praxis en el campo de la ciencia y la ética, y la necesidad de comprender a la objetividad científica y la subjetividad ética como formas diversas de conocimiento humano rigurosos.
untitled protocol v1
Authors: Marcos Sanches José , César Giraldo Paulo , Amaral Rose , Nogueira Eberlin Marcos , de Azevedo Marques Lygia , Migliorini Isabel , Nakahira Marcel , Jan Marinus Bieleveld Michel , Garcia Discacciati. Michelle
Published: July 2018

Objective: To characterize the lipid profile in vaginal discharge of women with vulvovaginal candidiasis, cytolytic vaginosis, or no vaginal infection or dysbiosis. Design: Cross-sectional study. Setting: Genital Infections Ambulatory, Department of Tocogynecology, University of Campinas, Campinas, São Paulo–Brazil. Sample: Twenty-four women were included in this study: eight with vulvovaginal candidiasis, eight with cytolytic vaginosis and eight with no vaginal infections or dysbiosis (control group). Methods: The lipid profile in vaginal discharge of the different study groups was determined by liquid chromatography-mass spectrometry and further analyzed with MetaboAnalyst 3.0 platform. Main Outcome Measures: Vaginal lipids concentration and its correlation with vulvovaginal candidiasis and cytolytic vaginosis. Results. PCA, PLS-DA and hierarchical clustering analyses indicated 38 potential lipid biomarkers for the different groups, correlating with oxidative stress, inflammation, apoptosis and integrity of the vaginal epithelial tissue. Among these, greater concentrations were found for Glycochenodeoxycholic acid-7-sulfate, O-adipoylcarnitine, 1-eicosyl-2-heptadecanoyl-glycero-3-phosphoserine, undecanoic acid, formyl dodecanoate and lipoic acid in the vulvovaginal candidiasis group; N–(tetradecanoyl)-sphinganine, DL-PPMP, 1-oleoyl-cyclic phosphatidic, palmitic acid and 5-aminopentanoic acid in the cytolytic vaginosis group; and 1-nonadecanoyl-glycero-3-phosphate, eicosadienoic acid, 1-stearoyl-cyclic-phosphatidic acid, 1-(9Z,12Z-heptadecadienoyl)-glycero-3-phosphate, formyl 9Z-tetradecenoate and 7Z,10Z-hexadecadienoic acid in the control group. Conclusions: Lipids related to oxidative stress and apoptosis were found in higher concentrations in women with vulvovaginal candidiasis and cytolytic vaginosis, while lipids related to epithelial tissue integrity were more pronounced in the control group. Furthermore, in women with cytolytic vaginosis, we observed higher concentrations of lipids related to bacterial overgrowth.
Adult mouse kidney dissociation (on ice) v6
Authors: Potter Andrew
Published: July 2018

Protocol for adult (8-10 week) mouse kidney dissociation performed on ice to reduce artifact gene expression. The first layer, consisting of collagenase digestion, breaks down the tissue and releases some cells and glomeruli and tubules. The second layer consists of bacillus licheniformis digestion for 15 min. augmented with a thermomixer at 1400 RPM and passaging with a 27 gauge needle. The second layer is meant to thoroughly break up remaining tubules and glomeruli, releasing cells such as podocytes. The final yield is 250K cells from 18 mg tissue with 98% viability, approximately 14,000 cells/mg tissue. Approximately 1% of released cells are podocytes (visualized using kidneys from MAFB-GFP+ mice using a hemocytometer).
Adult human small intestine cell dissociation (on ice) v7
Authors: Potter Andrew
Published: July 2018

Protocol for human small intestine cell dissociation, performed on ice to reduce artifact gene expression.
Two Stories of King Midas in the Judeo-Spanish Speaking World: Isak Papo and Matilda Koén-Sarano’s Versions of the ATU782 «Midas and the Donkey’s Ears», and ATU775 «Midas’ Short-sighted Wish» / Dos cuentos del rey Midas en la tradición oral judeoespañola: las versiones de Isak Papo y Matilda Koén-Sarano del ATU782 «Midas y las orejas de asno» y ATU775 «El rey Midas y el toque de oro»
Authors: Jovanovic Zeljko
Published: July 2018

En este artículo se analizan los dos tipos de cuentos conocidos como ATU782 «Midas y las orejas de asno», y ATU775 «El rey Midas y el toque de oro» entre los hablantes de judeoespañol. Los dos ejemplos incluidos aquí —uno procedente de Bosnia y publicado por Isak Papo, y el otro de Grecia recogido por Matilda Koén-Sarano— representan ejemplos de estos cuentos, raros en la lengua judeoespañola, y muestran claramente cómo la tradición sefardí continuó su desarrollo hasta finales del siglo XX, incorporando nuevos elementos que no existían en la tradición anterior. Me centro en subrayar cómo estos cuentos han sido adaptados al entorno sefardí y cómo se han introducido cambios sustanciales en el núcleo de ambos, con resultados diferentes.
Los motes y apodos como ejemplo de realidad lingüística y social. El mote en la provincia de Guadalajara / Monikers and Nicknames Illustrating Linguistic and Social Reality. Nicknames in the Province of Guadalajara
Authors: López de los Mozos Jiménez José Ramón
Published: July 2018

Con este artículo queremos ofrecer una visión del apodo como realidad lingüística y social en los pueblos de la provincia de Guadalajara. Recuperamos una colección muy poco conocida de apodos, e identificamos algunos rasgos de la poética del género.
El cuento de El joven pastor en poder de los asaltantes (ATU 958) a la luz de nuevos testimonios en el norte de África / The Tale of El joven pastor en poder de los asaltantes (ATU 958) in Light of New Testimonies in North Africa
Authors: Abenójar Óscar
Published: July 2018

En el presente artículo se publican cuatro versiones bereberes del cuento El joven pastor en poder de los asaltantes que nos obligarán a replantearnos las teorías acerca del origen y de la distribución del relato. Estas variantes –que fueron recogidas en una minúscula región montañosa del norte de Argelia– despliegan una diversidad de motivos y de personajes incluso superior al conjunto de paralelos de todo el continente europeo.
Tiempo para la burla obsceno-escatológica. Las sandingas: fiesta, sexualidad e inversión del orden en un pueblo de Andalucía / Time for Obscene-Scatological Jeer. Sandingas: Festival, Sex and Inversion of Order in an Andalusian Village (Spain)
Authors: Del Campo Tejedor Alberto
Published: July 2018

Durante la fiesta de la Candelaria (2 de febrero), los habitantes de La Puebla de los Infantes (Sevilla) celebran en torno a hogueras de olivo —candelas­—, en las que queman muñecos y singulares escenografías satíricas, mientras hombres y mujeres cantan sandingas, un tipo de copla eminentemente burlesca, donde cabe la pulla obscena y escatológica, considerada la sal y pimienta de la reunión festiva. Vinculando estas costumbres carnavalescas al tiempo liminar de turbulencia festiva que antecede al inicio de la primavera, este artículo se afana por comprender la lógica de degradación simbólica y renovación cósmica que subyace a las picantes canciones a través de las que los vecinos de La Puebla ­—y muy particularmente las mujeres— se divierten fustigando a la suegra, a la vecina, pero sobre todo al sexo opuesto, con el que se entabla una lucha ritual que pone de relieve el arcaico sentido apotropaico de la risa y la obscenidad, así como la creencia en la potencia fertilizadora que habría de nacer de la pugna de fuerzas contrarias pero complementarias.
Short-term and long-term outcomes of laparoscopic right hemicolectomy with d3 lymph node dissection: experience of one clinic
Authors: Rakhimov O. A. , Gordeev S. S. , Aliev V. A. , Mamedli Z. Z. , Kuzmichev D. V. , Barsukov Yu. A. , Rasulov A. O.
Published: July 2018

Objective: to assess short-term and long-term outcomes of right hemicolectomy with extensive lymph node dissection using the experience of one clinic.

Materials and methods. This retrospective study analyzed data from a prospectively collected database containing information on all patients with right-sided colon cancer that underwent laparoscopic right hemicolectomy with D3 lymph node dissection between 2013 and 2018. We estimated intraoperative blood loss, surgery duration (taken from anesthetic records), frequency of postoperative complications, length of in-hospital stay, duration of lymphorrhea, time to gastrointestinal recovery, integrity of the mesocolon, number and location of removed lymph nodes.

Results. A total of 50 underwent laparoscopic right hemicolectomy with D3 lymph node dissection. No cases of surgical conversion were registered. Median surgery duration was 185 min; median blood loss was 30 mL. No postoperative mortality was observed in the study cohort. Twelve (24 %) patients had postoperative complications; 2 (4 %) patients underwent repeated surgery. Median number of lymph nodes examined was 26; high-quality specimens (G ) were obtained in 48 (96 %) patients. At a median follow-up of 19.5 months, 2 (4 %) patients had disease progression (developed liver metastases).

Conclusion. Our results confirm safety of laparoscopic approach for right colon resection with D3 lymph node dissection
Impact of anastomotic leakage on outcomes in patients with rectal cancer
Authors: Rybakov E. G. , Shelygin Yu. A. , Таraso M. A. , Аlekseev M. V. , Kashnikov V. N.
Published: July 2018

Background. The effect of anastomotic leakage (AL) on oncological outcomes after total mesorectumectomy is controversial.

Objective: to investigate the influence of AL and other factors on oncological outcome.

Materials and methods. Data of 67 patients underwent total mesorectumectomy with normal healing were compared with those for 16 patients who experienced AL. Long-term oncological outcomes were analysed.

Results. Median follow-up was 43 months. AL rate was 19.4 % (16 cases out of 83). Following factors had negative influence on lower 4-year disease-free survival rate and reached statistical significance in univariant analysis: tumor invasion (hazard ratio (HR) 8.8; 95 % сonfidence interval (CI) 1.4–13.7; р= 0.01), metastases in regional lymph nodes (HR 3.5; 95 % CI 1.2–12.3; р= 0.03), tumor stage (р= 0.048), level of tumor differentiation (HR 0.1; 95 % CI 0–0.6; р<0.0001), tumor stenosis (HR 8.8; 95 % CI 1.4–13.7; р= 0.002), AL (HR 3.9; 95 % CI 1.6–37.1; р= 0.01). In the logistic regression analysis independent risk factors for the development of recurrence were not revealed.

Conclusion. AL was not proved to be a risk factor of worse oncological outcome. Hence, additional adjuvant treatment or extended follow-up on the basis of the occurrence of AL after low anterior resection of rectal cancer might not be justified.
Emergency resections in patients with complicated rightand left-sided colon cancer: long-term outcomes
Authors: Schaeva S. N.
Published: July 2018

Objective: to evaluate five-year overall and relapse-free survival in patients with complicated rightand left-sided colon cancer that underwent emergency resection.

Materials and methods. The study included 501 patients with urgent complications of rightand left-sided colon cancer that underwent emergency resection. The data was obtained from an electronic register containing the information on patients with urgent complications of colorectal cancer treated in general and specialized surgical hospitals in Smolensk between 2001 and 2013 (13 years). We assessed fiveyear overall and relapse-free survival in these patients.

Results. A total of 501 resections were performed during the study period. We observed significant differences in resection statuses of patients after emergency resection: the R1 resection status was more frequent in individuals with right-sided colon cancer compared to those with left-sided colon cancer (20.8 % vs. 6.9 %, p = 0.0002). Mean number of lymph nodes examined was 4.6 ± 2.0 in patients with right-sided cancer and 5.3 ± 3.0 in patients with left-sided cancer (p = 0.18). There were no differences in the number of patients receiving adjuvant treatment between the groups (p = 0.11). Patients with left-sided stage II/IIIB/IIIСcomplicated colon cancer demonstrated better overall and relapse-free survival than those with right-sided tumors of the same stages (overall survival: p = 0.007, p = 0.0002, p = 0.0001 for stages II, IIIB, IIIСrespectively; relapse-free survival: p = 0.005, p = 0.0003, p = 0.0002 for stages II, IIIB, IIIСrespectively).

Conclusion. The observed differences in the outcomes of treatment for rightand left-sided complicated colon cancer can be explained by the fact that the majority of emergency resections for right-sided tumors were one-stage and were performed in general surgery hospitals. Patients with left-sided cancer underwent tumor removal on the second stage more often than those with right-sided cancer (32 % vs. 13 %). Treatment of patients with complicated colon cancer should be consistent, stepwise, and pathogenetically reasonable.
A recepção (praticamente) perdida: a Tebaida de José Agostinho de Macedo – apresentação e edição
Authors: Cardoso Leandro Dorval
Published: July 2018

Tomando como fonte o manuscrito CXXII 2-2 da Biblioteca de Évora, este artigo traz à luz, em edição diplomática, o único fragmento conhecido da tradução integral do poema épico Thebais, de Públio Papínio Estácio (Publius Papinius Statius – séc. I d.C.), realizada por José Agostinho de Macedo e perdida antes que pudesse ter sido publicada. Para isso, em um primeiro momento, este artigo empreende um breve percurso pela biografia de Macedo, em especial por sua postura crítica e suas ideias sobre a tradução, com o objetivo de delinear um horizonte no qual e a partir do qual seu trabalho com o poema de Estácio possa ser compreendido. Dessa forma, será possível ressaltar a imagem do autor como uma figura importante na recepção dos clássicos greco-latinos em língua portuguesa.
COMPARATIVE ANALYSIS OF COST OF DRUG THERAPY OF THE MOST HIGH-COST ONCOLOGICAL DISEASES IN MOSCOW
Authors: Poliakova К. I. , Holownia-Voloskova M. E. , Byakhov M. Yu. , Ermolaeva T. N. , Fisun A. G. , Dubovtseva V. A. , Olyushina E. M. , Davydovskaya M. V. , Kokushkin K. A.
Published: July 2018

Objectives.According to literature and experts, prostate cancer (PC), breast cancer (BC), colon cancer (CC), melanoma (MEL) and renal cell carcinoma (RCC) are the most high-cost oncological diseases. The aim of our study was to calculate the charges for each of these nosologies from the point of view of Moscow’s budget and compare them with each other.

Methods.To assess the annual costs of drug therapy in Moscow in patients with PC, BC, CC, MEL and RCC there has been developed an analytical model in MS Excel software, considering the data of Cancer Register, as well as literature sources.

Results.There has been estimated that if the costs of drug therapy for all five of assessed types of cancer are taken as 100 %, then the most costly is BC (41 % of costs), then MEL (20 %), RCC (15 %), CC (13 %) and PC (12 %). There has been also calculated, that if the number of patients with all five types of assessed cancer undergoing drug therapy, we would consider as 100 %, the highest percentage of them is in BC (50 % of all patients), then PC (36 %), CC (9 %), MEL (3 %) and RCC (1 %).

Conclusions. The structure of drug therapy costs in patients with PC, BC, MEL, CC and RCC in Moscow shows that the most expensive is the treatment of patients with melanoma (for 3 % of patients Moscow City Health Department spends 20 % of charges) and RCC (1 % of patients spends 15 % of charges).
ULTRASOUND TUMOR ABLATION: IMMUNE EFFECTS AND PERSPECTIVES OF INTEGRATION IN THE MODERN TREATMENT OF ADVANCED CANCER
Authors: Machak G. N.
Published: July 2018

Despite significant progress in molecular oncology and immuno-oncology, only 20-30 % of patients with advanced cancer can be cured with modern treatments indicating that new approaches are needed. Further improvements in immunotherapy of cancer are associated with enhanced tumor immunogenicity, induction of inflammatory phenotype and inhibition of immune suppression at the tumor microenvironment level. In this context, high-intensity focused ultrasound (HIFU) ablation have several advantages, particularly it is able to elicits a rapid clinical and immune response, is non-invasive, have low local morbidity, allows repeated sonications, have relative low cost and does not require long hospitalization. In addition to cytoreduction and decreasing of systemic immune suppression, HIFU generates a tumor debris depot acting as vaccine in situ. Immunogenic cell death elicits a CD4+ and CD8+ cytotoxic T-cell response, but several regulatory mechanisms, particularly PD-1L expression, are promoted in response to enhanced immune cells infiltration of heated and distal tumors. This results in low rate of durable and clinically relevant abscopal effects. For these reasons HIFU is currently viewed as a part of strategies targeting multiple steps of cancer immune cycle (TLR agonists, GM-CSF, cytokines, CTLA-4, PD-1 / PD-1L inhibitors, T-cell co-stimulation agonists, adoptive cell therapy etc). Higher rate of abscopal effects and improved survival have been shown in some preclinical studies using thermal ablations in combination with immunotherapy. In this setting, there is an opportunity to use check-point inhibitors in reduced doses. In addition, tumor ablation after non-effective immunotherapy could induce a new cancer antigens spreading, T-cell repertoire changes and enhance tumor responsiveness to treatment. Based on encouraging preclinical data, this exiting approach is currently explored in some ongoing trials aiming to evaluate the optimal treatment sequences and its clinical efficacy.
TWO-STAGE DELAYED RECONSTRUCTION IN PATIENTS WITH BREAST CANCER AFTER MASTECTOMY
Authors: Zikiryahodzhaev A. D. , Rasskazova E. A.
Published: July 2018

Delayed breast reconstruction after performing radical mastectomy for cancer is a surgical method of rehabilitation of patients. Breast reconstruction is performed to improve the quality of life of patients with breast cancer. Breast restoration using expander is used in women with a small breast size, as well as in patients who refuse to use patchwork techniques of breast restoration. In P. A. Herzen MORI 27 patients with a diagnosis of breast cancer was performed in delayed breast reconstruction after radical mastectomy.

To achieve symmetry in 51,9 % of cases the operations were also performed on the healthy breast. During the observation period up to 4 years, no signs of progression of the underlying disease were found in this group.
SPK’DAN BAĞIMSIZ DENETİM YETKİSİ ALMIŞ DENETİM ŞİRKETLERİNDEKİ DENETÇİLER AÇISINDAN YARATICI MUHASEBE UYGULAMALARININ DEĞERLENDİRİLMESİ
Authors: GENÇ Murat
Published: July 2018

Enron,
Worldcom gibi dünya çapında faaliyet gösteren büyük şirketlerin iflası ile
sonuçlanan süreçte, bağımsız denetim şirketlerinin önemli bir rol üstlendiği
ortaya çıkmıştır. Şirketlerin finansal durumlarını yaratıcı muhasebe (YM)
uygulamalarıyla değiştirmesi, bağımsız denetime olan güveni sarsmış ve bunun
sonunda uluslararası birçok düzenleme yapılmıştır.

YM
uygulamalarının bağımsız denetçiler tarafından değerlendirildiği bu çalışmada;
bağımsız denetçilerin YM uygulamalarını nasıl algıladıklarını, hangi YM türleri
ile sıklıkla karşılaştıklarını, karşılaştıkları YM uygulamalara başvuran
şirketlerin genel özelliklerinin ne olduğunu ve bağımsız denetçinin YM
uygulamaları karşısında yasal, mesleki, bağımsızlık, denetim faaliyeti ve
etiksel açıdan sorumlulukları yapılan anket çalışmasıyla belirlenmeye
çalışılmıştır. Buna göre; bağımsız denetçilerin YM’yi hile ile aynı anlamda
değerlendirmediği, giderlerin azaltılması amacıyla kullanılan YM ile daha sık
karşılaştıkları, YM uygulamalarını önlemek bakımından denetçinin sorumluluk
bilinci ile hareket ettiği tespit edilmiştir. Sonuçlara göre; YM’nin
sınırlarının bağımsız denetim açısından belirlenmesi gerektiği ortaya
çıkmıştır.
DOĞRUDAN YABANCI YATIRIMLAR VE EKONOMİK BÜYÜME İLİŞKİSİ: BRICT ÜLKELERİ PANEL NEDENSELLİK ANALİZİ
Authors: ÖNCÜ Erdem , ÇELİK Şaban
Published: July 2018

Bu çalışmada doğrudan yabancı yatırımlar ile ekonomik büyümenin arasındaki
ilişki BRICT( Brezilya, Rusya, Hindistan, Çin, Türkiye) ülkelerinin 1998-2016
dönemi için panel birim kök ve nedensellik testleri ile araştırılmıştır. Öncelikle,
serilerin yatay kesit bağımlılığı incelenmiş ve sonrasında birim kök testleri
uygulanmıştır. Dumitrescu ve Hurlin (2012) nedensellik testi sonuçlarına göre, doğrudan
yabancı yatırımlardan ekonomik büyümeye doğru nedensellik ilişkisinin olmadığı
fakat ekonomik büyümeden doğrudan yabancı yatırımlara doğru bir nedensellik
ilişkisinin bulunduğu görülmüştür. Bu çalışmada bulunan sonuçlar Hansen vd.
(2003) ve Kahveci ve Terzi (2017) çalışmalarında bulunan sonuçlar ile
paralellik göstermektedir. Ayrıca, 2008 yılının verilerinin kullanılmadığı
analizde doğrudan yabancı yatırımlar ve ekonomik büyüme arasında çift yönlü
nedensellik ilişkisi görülmüştür. Bu çalışmada olduğu gibi, Duarte vd. (2017) çalışmasında
da değişkenler arasında çift yönlü ilişki bulunmuştur.
POZİTİF PSİKOLOJİK SERMAYENİN İŞE YABANCILAŞMA ÜZERİNDEKİ ETKİSİ
Authors: AYDEMİR Ceren , AKDOĞAN Ayşegül Asuman
Published: July 2018

İnsan kaynağının örgütler açısından öneminin artması ile birlikte insanın etkin bir biçimde çalıştırılabilmesi için neler yapılması gerektiği konusundaki çalışmalar daha da önem kazanmaya başlamıştır. Son yıllarda, bu konuda öne çıkan yaklaşımlardan bir tanesi pozitif psikolojidir. Sorunların çözülmesinde pozitif davranışların geliştirilmesi esasına dayanan pozitif psikoloji akımı bireylerin güçlü ve pozitif yanlarına odaklanarak potansiyellerinin ortaya çıkarılması gerektiğini savunmaktadır. Bu mantıkla geliştirilmiş olan pozitif psikolojik sermaye kavramı araştırmalara konu olmaya devam etmektedir. Günümüzde çalışanların en önemli sorunlarından biri olarak değerlendirilen işe yabancılaşma çalışan performansını düşürmekte, bu durum örgütsel performansı da olumsuz yönde etkilemektedir. Bu yüzden işe yabancılaşmanın ortadan kaldırılması veya en aza indirilmesi için bireysel ve örgütsel birtakım önlemlerin alınması gerekmektedir. Bu çalışmanın amacı, pozitif psikolojik sermayenin işe yabancılaşma üzerindeki etkisini belirlemektir. Bu amaç doğrultusunda, araştırmaya katılan 339 akademisyenden elde edilen verilerle analizler yapılmıştır. Araştırma sonuçlarına göre, pozitif psikolojik sermayenin işe yabancılaşma üzerinde anlamlı bir etkisi vardır. Ayrıca iki kavram arasında negatif yönlü bir ilişki mevcuttur.
Completing the puzzle: Another species of Rhaucus Simon, 1879 (Arachnida: Opiliones: Cosmetidae) from Colombia
Authors: García Andrés F. , Ahumada-C. Daniela
Published: July 2018

Se revalidó la combinación restaurada de Rhaucus papilionaceus (Simon, 1879) según lo indicado previamente por Henriksen (1932). Se ofrece una nueva descripción de la especie, incluidas imágenes tomadas con microscopio electrónico de barrido (Scanning Electron Microscopy, SEM) y un mapa de distribución. Esta especie representa la sexta especie válida del género y extiende su rango altitudinal a los bosques bajos en los Andes colombianos (1.500 m.s.n.m.). © 2018. Acad. Colomb. Cienc. Ex. Fis. Nat.
Efecto de la cobertura vegetal de ribera en las comunidades ícticas en el bosque húmedo premontano y muy húmedo premontano del Alto Magdalena, Colombia
Authors: Poveda Cuellar José Luis , López-Delgado Edwin Orlando , Villa-Navarro Francisco A.
Published: July 2018

El objetivo de este estudio fue determinar la influencia de la cobertura vegetal en la composición, la estructura y la diversidad de la ictiofauna en las quebradas de las zonas de vida de los bosques húmedo premontano (bh-PM) y muy húmedo premontano (bmh-PM) del Alto Magdalena, Colombia. Para esto, se muestrearon 23 estaciones distribuidas en las coberturas vegetales de pastos, mosaico de cultivos, arbustos y bosques en las diferentes zonas de vida. En cada estación se establecieron transectos longitudinales (100 m/ancho variable); los peces se capturaron con un equipo de pesca eléctrica y una red de arrastre (5 m x 1,5 m, ojo  de malla de 0,05 m), y se evaluaron paralelamente algunas variables ambientales. La estructura y la diversidad de la ictiofauna se calcularon mediante el uso de modelos estándar. En cuanto a la diversidad, medida con números de Hill, no hubo diferencias significativas entre las coberturas vegetales en el bh-PM. Sin embargo, en el bmh-PM la cobertura de pastos fue la más diversa. En el análisis de escalamiento multidimensional no métrico, no se evidenciaron diferencias en la estructura del ensamblaje de peces en los tipos de cobertura vegetal, sin embargo, en el análisis canónico de correspondencias se evidenció que la cobertura de dosel, la calidad de la vegetación de ribera y la elevación influyeron de manera significativa en la composición y la distribución de la ictiofauna. Si bien la cobertura de pastos presentó la mayor diversidad íctica, es un hábitat con degradación del bosque de ribera y cambios en la temperatura, idóneo para el establecimiento de especies tolerantes e invasoras. © 2018. Acad. Colomb. Cienc. Ex. Fis. Nat.
An Investigation of Litigation Process in Construction Industry in Turkey
Authors: ÇEVİKBAŞ Murat , KÖKSAL Almula
Published: July 2018

Projects are laden with variety of uncertainties depending on their unique characteristics. Construction projects have their own
distinctive qualifications and technology. Thereby, unspecialized legal
professionals on the subjects of construction related cases would lead the
judicial process to settle on unhealthy basis. In this study, it is aimed to classify
disputes related to construction sector to distinguish the most frequent
dispute sources and to identify the competency level and qualification of
concerned judicial actors. Correspondingly, 282 cases between 2007 and
2017 in Turkey have been classified to relevant contents and analysed. In
conclusion, contract contents, civil projects, contracts between employers and
contractors, debits and credits related disputes have been detected as the most
frequent dispute sources under the main contents. Secondly, in majority of the
cases, reassessment has been given by Court of Cassation due to inadequate
competency level of Courts of First Instance and expert witnesses.
Ataque de lagartas em estilo-estigma e grãos da espiga de diferentes híbridos de milho-Bt
Authors: Suekane Renato , Degrande Paulo Eduardo , Zeviani Walmes Marques , Lima Junior Izidro Dos Santos de
Published: July 2018

A cultura do milho é atacada por diversas pragas ao longo do seu ciclo e recentemente foi constatada a ocorrência de Helicoverpa armigera atacando espigas de milho no Brasil. O objetivo do trabalho foi avaliar o ataque de lagartas em estilo-estigma e grãos da espiga de diferentes híbridos de milho-Bt. O estudo foi realizado no município de Dourados (MS). Avaliaram-se os insetos encontrados nos estilos-estigma presentes em cinco espigas de milho por parcela. Foram realizadas três avaliaçõesdos estilos-estigma e uma quarta avaliação dos danos nas espigas do milho. Houve diferença estatística significativa entre o número de lagartas de Spodoptera frugiperda encontradas no estilo-estigma dos híbridos estudados. Ocorreu um maior número de lagartas no híbrido de milho não-Bt, próximo de 0,5 lagartas/estilo-estigma, seguido do híbrido de milho Cry1Ab, Cry1A.105, Cry2Ab2 e por último o menos infestado, com a proteína VIP3Aa20. O híbrido de milho que expressa a proteína VIP3Aa20 apresentou menor número de lagartas no estilo-estigma.
Metacognição e o ensino e aprendizagem das ciências: uma revisão sistemática da literatura (RSL)
Authors: Cleophas Maria Das Graças , Francisco Welington
Published: July 2018

O objetivo deste artigo é apresentar resultados oriundos de Revisão Sistemática da Literatura (RSL) sobre pesquisas relacionadas ao uso da metacognição na Educação em Ciências. Foram utilizados como fonte de pesquisa vinte periódicos vinculados à área de Ensino das Ciências. Para o levantamento dos dados, foi criado e aplicado o Modelo Sistemático para Pesquisas em Bancos de dados com Acesso Livre (MSPBAL). Ao todo, foram levantados 76 artigos referente à temática investigada entre 10.986 trabalhos analisados. Os artigos foram estudados sob dois processos adotados para categorização: 1) aspectos gerais e, 2) dimensão de análise e suas divisões categoriais vinculadas à noção de metacognição. Os resultados apontam que as pesquisas no campo da metacognição são discretas e há necessidade de aprofundamento teórico e empírico, que exibam, por exemplo, resultados de pesquisas utilizando estratégias metacognitivas que demonstrem seus benefícios para a construção do conhecimento dos indivíduos sobre as Ciências Naturais e da avaliação desse conhecimento.
Aproximações entre o monitoramento metacognitivo e a elaboração de portfólio em uma disciplina de Química Geral
Authors: Locatelli Solange Wagner , Alves Natália Cristina Barbosa
Published: July 2018

O presente artigo tem como objetivo verificar as possibilidades do uso do portfólio pedagógico associado ao monitoramento metacognitivo de Flavell (1979), por meio da autoavaliação e autorregulação propiciadas aos estudantes por essa ferramenta, mediadas por devolutivas e orientações dadas constantemente pela docente. Foi feito um estudo de caso de um estudante da Universidade Federal X ao longo de uma disciplina de Química Geral. Foram analisados os registros semanais feitos pelo aluno após cada aula, com suas percepções e autoavaliações e também observou-se o aproveitamento demonstrado nas duas provas aplicadas na disciplina. Os resultados indicam uma melhora de desempenho e de atitude do estudante, com sua participação ativa no processo, proposições de estratégias mais adequadas ao seu estudo e uma melhor organização devido ao monitoramento metacognitivo proposto neste estudo. Assim, verificou-se que é possível fazer a aproximação do uso dos portfólios em sala de aula com o referencial de John Flavell sobre o monitoramento metacognitivo e que o portfólio, assim como sua condução pela docente, teve uma participação positiva no processo de aprendizado dos conteúdos da disciplina de Química Geral pelo aluno analisado.
Metacognição, ensino-aprendizagem e formação de professores de ciências
Authors: Brabo Jesus Cardoso
Published: July 2018

São apresentadas algumas razões da importância do desenvolvimento de pesquisas sobre Metacognição e aplicações dos princípios teóricos derivados na elaboração de estratégias de ensino-aprendizagem de alunos e professores de ciências e matemática. Também são apresentados e categorizados os artigos selecionados para esta edição especial.
Breve análisis a los "paradigmas clásicos del nacionalismo" = Brief analysis to the "classic paradigms of nationalism"
Authors: Reyes Pascual Guillermo
Published: July 2018

RESUMEN: Los eventos que han acontecido en varios lugares del continente europeo, como Kosovo, el este de Ucrania, Escocia, Cataluña, o más recientemente Córcega, han tenido como principal consecuencia el resurgimiento de la discusión, dentro del debate político, en torno a la nación y su condición de elemento legitimador de la comunidad política. Para darle sentido a esta discusión, este artículo desgrana brevemente los principales paradigmas del nacionalismo para poder identificar y situar a los diferentes actores dentro del debate teórico en torno a la nación. ABSTRACT: The events that have taken place in various parts of the European continent, such as Kosovo, eastern Ukraine, Scotland, Catalonia, or more recently Corsica, have had as a main consequence the resurgence of the discussion, within the political debate, around the nation and its condition as the legitimating element of the political community. To make sense of this discussion, this article briefly breaks down the main paradigms of nationalism in order to identify and place the different actors within the theoretical debate around the nation.PALABRAS CLAVE: paradigmas clásicos del nacionalismo, primordialismo, modernismo, perennialismo, etnosimbolismo.KEYWORDS: classic paradigms of nationalism, primordialism, modernism, perennialism, ethnosymbolism.
Determinantes das colaborações inventivas nas redes brasileiras de copatenteamento inter-regional e internacional
Authors: Reis Raquel Coelho , Gonçalves Eduardo , Taveira Juliana Gonçalves
Published: July 2018

O presente artigo objetiva investigar os determinantes regionais e estruturais do número de ligações entre regiões nas redes de colaborações inventivas brasileiras. Para tanto, utilizam-se dados de copatenteamento entre inventores brasileiros e entre brasileiros e estrangeiros. Como possíveis determinantes do número de ligações, consideram-se tanto os aspectos econômicos quanto os tecnológicos e de densidade demográfica das regiões, além das estruturas de ligações dos nós nas redes. A investigação é realizada com o modelo para dados de contagem, Binomial Negativo Inflado em Zeros (ZINB). Como principais resultados, contatou-se que a formação de laços inter-regionais de patenteamento é afetada positivamente pelo número de ligações internas à região, pela escala de inventores, pelo potencial de realizar P&D empresarial e universitário e, principalmente, pelo grau de centralidade da região. No caso das redes internacionais, realizadas entre inventores brasileiros e estrangeiros, os laços são positivamente afeta os apenas por potencial de P&D, especialmente o empresarial, e grau de centralidade. Além disso, nota-se que o grau de internacionalização de uma rede afeta positivamente o estabelecimento de redes inter-regionais.
La influencia de los roles de género en el consumo de alcohol: estudio cualitativo en adolescentes y jóvenes en Asturias
Authors: Fernández Rodríguez María Aránzazu , Dema Moreno Sandra , Fontanil Gómez Yolanda
Published: July 2018

A pesar del desarrollo de políticas de prevención dirigidas a abordar el consumo de alcohol en adolescentes y jóvenes, durante la última década se ha producido un aumento considerable de quienes realizan un consumo abusivo de esta sustancia en España. Las encuestas oficiales sobre este fenómeno muestran un acercamiento entre varones y mujeres en las prevalencias de consumo y en los consumos de riesgo, e incluso una mayor incidencia de estas conductas en el caso de las mujeres al final de la etapa adolescente. El objetivo de este artículo es conocer la influencia que ejercen los roles de género en estas pautas de consumo en adolescentes y jóvenes. Para ello, se han realizado grupos focales que han permitido identificar las similitudes y diferencias que se producen tanto en las prácticas de consumo y abuso del alcohol que desarrollan estos colectivos, como en el significado social que unos y otras atribuyen a las citadas prácticas.  Los resultados obtenidos muestran que las variables género y edad actúan de forma combinada en el aprendizaje del consumo de bebidas alcohólicas, así como en las motivaciones y expectativas que los y las adolescentes y jóvenes tienen sobre dichas prácticas. Además, en este estudio se identifican tres etapas diferenciadas, en la primera de ellas los roles de género se encuentran claramente definidos, en la segunda se observa cierta transgresión de los mismos fundamentalmente por parte de las mujeres y en la última se advierte una vuelta a los tradicionales roles de género.
Gambling Motives Questionnaire validation in adolescents: Differences based on gambling severity and activities.
Authors: Grande Gosende Aris , Martínez Loredo Víctor , Fernández Hermida José Ramón
Published: July 2018

Self-reported reasons for gambling have been highlighted as crucial to understanding why adults develop problems with gambling. However, research on motives among adolescents remains scarce. The aim of this study is to explore the factorial structure of the Gambling Motives Questionnaire (GMQ) and to analyze differences in motives among adolescents, depending on the gambling activity and level of gambling severity. A total of 698 adolescent gamblers (M = 15.24, SD = .76) were assessed. As well as the GMQ, the South Oaks Gambling Screen (SOGS-RA) questionnaire was used. Gamblers were classified into three categories (strategic, non-strategic, and mixed) according to the activities engaged in during the last year. An Exploratory Factor Analysis was conducted followed by a Confirmatory Factor Analysis in order to explore the internal structure of the GMQ. Three two-way between-groups Analyses of Variance (ANOVA) were conducted to explore differences in motives according to the type of activity and the gambling severity levels. According to the factorial structure of the GMQ, three main groups of motivations were found: enhancement, coping and social. Compared to non-problem gamblers, problem gamblers scored higher on all motives. Moreover, gamblers seeking enhancement prefer strategic games, those gambling to cope with stress use non-strategic games more frequently, while social gamblers do not show a preference for either strategic or non-strategic games. In conclusion, gambling motives are related to gambling severity and structural characteristics of gambling. These findings may be useful from a prevention standpoint.
The Effect of Fencing the Forest Regeneration Stages upon the Level of Damage Caused by Deer in the Lowland Forests of South-Western Poland
Authors: Bobek Bogusław , Furtek Jakub , Merta Dorota , Wojciuch-Płoskonka Marta
Published: July 2018

In the lowland forests of south-western Poland, the effect of the fencing of forest regeneration stages, aged up to 20 years, upon the level of damage inflicted by red deer (Cervus elaphus), fallow deer (Dama dama), and roe deer (Capreolus capreolus) in non-fenced patches of this age class of forest was studied. In the studied forest districts (n=4), there was the highest proportion of the mixed coniferous‑deciduous forest types, where the main forest‑forming tree species were pine (Pinus sylvertris), birch (Betula sp.), oak (Quercus sp.), beech (Fagus sylvatica), and spruce (Picea abies). At the forest district level, the percentage of fenced areas in young forest plantations (1‑10‑year old) ranged, on average, from 9.1-30.9%, and that in tickets (11-20‑year old) ranged from 0.0%-10.2%. The percentage of areas of severely damaged young plantations fluctuated between 5.7 and 14.2%, and that of tickets fluctuated between 0.3-12.9%. For young plantations, a statistically significant correlation (“r” ranged from 0.51-0.75) was obtained between percentage of area in fenced plots and the level of damage caused by deer. For thickets, this correlation was obtained solely in Pieńsk Forest District (r = 0.646). In the studied forest districts, the fencing of young plantations and thickets resulted in the reduction of average potential food base for cervids, from 2.9 to 10.0 %. An attempt was made to interpret the level of deer damage on the basis of an index, taking into account the standing crop of deciduous browse and forbs, and the population density of cervids.
The Rights Network: 100 Years of the Hohfeldian Rights Analytic
Authors: Clayton Thompson Jack
Published: July 2018

This paper sets out to reconsider the Hohfeldian framework of rights in celebration of the centenary anniversary of Hohfeld's death. It begins by conceptualising each of the Hohfeldian incidents or rights before outlining the molecular or complex structure of rights to ‘things’. I adopt a broad use of the term of ‘right’ and apply it to Legal, Moral, Equitable and Human conceptions and constructions. It sets out an argument in favour of a further definitional model - in addition to Hohfeld’s scheme of opposites and correlatives – which focuses on the function of these conceptual rights. Finally, it will consider the broader implications of how rights are held and the relationships which these rights govern. Ultimately, this paper seeks to demonstrate the benefit, and indeed necessity, of the Hohfeldian model in any discussion of rights. Without it ‘rights talk’ is debased and impoverished.
Heat and Mass Transfer Properties of Sugar Maple Wood Treated by the Thermo-Hygro-Mechanical Densification Process
Authors: Fu Qilan , Cloutier Alain , Laghdir Aziz
Published: July 2018

This study investigated the evolution of density, gas permeability and thermal conductivity of sugar maple wood during the thermo-hygro-mechanical densification process. The results suggested that the oven-dry average density of densified samples was significantly higher than that of the control samples. However, the oven-dry density did not show a linear increase with the decrease of wood samples thickness. The radial intrinsic gas permeability of the control samples was 5 to 40 times higher than that of densified samples, which indicated that the void volume of wood was reduced notably after the densification process. The thermal conductivity increased by 0.5 - 1.5% per percent increase of moisture content for densified samples. The thermal conductivity of densified wood was lower than that of the control samples. The densification time had significant effects on the oven-dry density and gas permeability. Both the densification time and the moisture content had significant effects on thermal conductivity, but their interaction effect was not significant.
The Impact of Working Relationships in the Accounting and Audit Cycle
Authors: Mohammadi Reza
Published: July 2018

This study evaluates literature on the wheel of audit partners in Chinese companies and institutions by examining the impact of relationships before and after the rotation between the input and output partners. We consider the partners in the rotation before the rotation, before the work relationship. We find two different results from the previous working relationships: (a) increasing the likelihood of the outgoing partners after the cooling period, and (b) reducing the quality of the audit and lower accounting after the rotation. These findings ask whether the rotational partners are truly independent of the working relationships.
Conquest of Bosnia in the Light of Ottoman Chronicles
Authors: SEYHAN Ayşe
Published: July 2018

Fatih Sultan Mehmed adopted
the understanding of dominance in the world which is an old Turkish tradition.
Fatih Sultan’s aim was to collect both Christian and Islam civilization under
his hegemony so that he can establish a global empire. Following the conquest
of Istanbul, Sultan Mehmed’s first initiative was to build a great and rich
center for his state that became an imperial force. Then, he wanted to abolish
the factors which might lay a claim on Istanbul. Furthermore, his political agenda was to abandon the regional
principalities system; and he wanted to conquest all principalities directly so
that he can establish a central empire. The Balkan Peninsula was a region that
should be under control against the western threats and at the same time it was
a gate to transfer the Turkish-Islam civilization to the west. He followed the way of abolishing the
principalities till Tuna so as to establish his dominance over the region; and
he combined all Balkan Peninsula in one entity. The besieging of Bosnia was one
of the initiatives towards this aim. In this research, conquest of Bosnia in
the period of the Mehmet II (1480), will be evaluated through the works of
classical Ottoman history writers such as Tursun Bey, Oruç Bey, İbn Kemal,
Solak-Zade Mehmed Hemdemî Çelebi.