bluuebunny/crossref_metadata_2025 huggingface dataset:
PERAN GEL LIDAH BUAYA DALAM MENGURANGI XEROSIS
Authors: Khoirini Fatimah
Published: January 2021

The management of patients with Chronic Renal Failure (CRF) is theimmediate treatment of the infection to prevent infection to the patient's kidney due todecreased immunity. CRF patients almost all have dermatological disorders, includingxerosis. Pharmacological treatment causes a lot of side effects. One natural ingredient isaloe vera. Aloe vera as a moisturizer, antibiotics and as well itching. This study aims toanalyze the effectiveness of aloe vera gel as a material alternative to nursingimplementations in xerosis CRF patients in Semarang hospitals. This type of research isexperiment with using pretest posttest control group design, selection sampling withrandom sampling taking random table. The number of respondents 36 people, that are 18people giving the control group a placebo gel skin lotion 2 times daily after bath for 3days and 18 people experimental group with the administration of aloe gel 2 times dailyafter bath for 3 days. Observations using Akhyani modifications observation sheet.Xerosis difference in the two groups were analyzed by paired samples T-test, while therelationship with the respondent characteristics xerosis is analyzed by independentsample T-test and corelations. Statistical test results showed no significant differencexerosis before and after administration of aloe vera gel with xerosis value (p =0.000).The implication of this study is the Aloe vera gel can be considered to bealternatives to nursing implementations xerosis patients with CRF.
EFEKTIFITAS MIKROORGANISME LOKAL (MOL) LIMBAH BUAH-BUAHAN SEBAGAI AKTIFATOR PEMBUATAN KOMPOS
Authors: Ali Haidina
Published: January 2021

Constraints or public complaints in the process of composting organic wastelies in the composting process that takes a long time between 2-3 months and acceptanceof people who are less fit to existing activator as EM4 scarce in Rural. The purpose of thisstudy was to determine the effectiveness of the Local Microorganisms activator (MOL)waste fruits of the length of time the formation of compost organic waste. This type ofresearch is an experimental design using "posttest with control". The results of the studythe average length of time (days) composting organic waste with the addition of MOLactivator dose of 10 mL for 24 days, a dose of 15 ml for 18.6 days, a dose of 20 mL for 15days, and a dose of 25 ml for 11.6 days. The addition of MOL activator with a dose of 25mL is the most effective dose in composting organic waste. Obtained p = 0.000 <α = 0.05;there were significant differences between the old time of the formation of the addition ofcompost activator Local Microorganisms (MOL) at a dose of activator 10 mL, 15 mL, 20mL and 25 mL. Expected research MOL activator use in composting organic waste can bea solution, especially for people in overcoming the problem of composting which takes along time.
KEJADIAN PNEUMONIA PADA BATITA DI WILAYAH KERJA PUSKESMAS SUKAMERINDUKOTA BENGKULU
Authors: Hartini Lela
Published: January 2021

Pneumonia is an infection or inflammation of the lower respiratory tract thatinvolves the alveoli and bronchioles. Risk factors for pneumonia which occurs in boysaged 1-3 years with a skinny body weight. Pneumonia is the leading cause of death ofinfants and toddlers in Indonesia with a total percentage (23.6%), which is the largestproportion of all-cause mortality in infants and toddlers. In the city of Bengkulu numberof events in 2014 pneumonia were 942 (6.07%), Sukamerindu health centre is first orderwith 51 people, Basuki Rahmat 47 people, and 39 people in Lingkar Barat. Purpose ofthis study was to determine the incidence of pneumonia in toddlers picture in PuskesmasSukamerindu in 2014. This study used a descriptive design, with a population of childrenaged 1-3 years which amounted to 51 people, technique data sampling was used TotalSampling, data collection secondary techniques, data obtained by existing records inhealth centers (patient registers). The results showed that the majority (60.8%) childrenaged 13-24 months, the majority (72.5%) child-sex male, and most (56.9%) children werein the category of lean body weight. It is recommended to parents, especially mothers tobe able to take precautions against the occurrence of pneumonia, such as providingadequate nutrition to children so that children are not malnourished which can increasethe risk of pneumonia
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN TINGKAT KEMANDIRIAN PENDERITA/KELUARGA TB PARU
Authors: Gustina Mely
Published: January 2021

Bengkulu city ranks fourth at 7,5%,the rate of TB(BTA+)first highs in publichealth service Sukamerindu,the second highest public health service Basuki Rachmad 25and hig hs into three PHC cage 19 people(Bengkulu City Health Office,2015),Beyond theinfluence of health against diseases such as pulmonary TB slum housing,moist facilitateTB bacteria to live and breed Government can facilitate and and development theoriessuch as Enabling,Empourment and Protecting. The autonomyof a society or group can bebased on the Ministry of Health 279/Menkes/SK/IV/2006. This study aimed correlationfactors that affect the level of independence with pulmonary tuberculosis?. Type of surveyresearch with cross sectional approach,the sample amounted to 31 obtained by purposivesampling technique,using univariate and bivariate analysis using Chay Square. Results ofstudy largely beyond health factors. Most of the level of independence of thepatient/family, there is a correlation factor protecting the activities of governmentfacilitation to the level of independence of the patient/family. Recomemended for patientswith medication adherence and trust health workers to patients/family as PMO when donewith a high awareness of the patient and family, it can accelerate healing.
ANALISIS PENERAPAN PENGELOLAAN KEUANGAN BADAN LAYANAN UMUM(PK-BLU) POLITEKNIK KESEHATAN KEMENKES BENGKULU
Authors: Riyadi Agung
Published: January 2021

fter two years of implementing the financial management of BLU, there is still themanager of the department / study program who do not understand the flexibility of financialmanagement that offers efficiency and productivity, have not seen the role of the supervisoryboard (a god) to the financial coaching BLU. Value turnover was still below the minimumrequirement, Operational Cooperation is still very minimal, opinions BLU is still small (under15 billion) and the remuneration of the BLU can not be granted to managers and employeesBLU officials. The purpose of this study was to determine the application overview ManagedHealth Polytechnic BLU MoH Bengkulu. This research was conducted with qualitative. Theunit of analysis of research data is Poltekkes MoH Bengkulu. The subject of research is theDirector, Pudir, Kasubbag Adum, Kaur Finance, kaur and Staff Officer, Treasurer BLU,Treasurer non-tax revenues, financial reporting staff, Ka. Planning Unit, Kajur/Sekjur,department managers, lecturers and students of each department / study program. Thesampling technique purposive sampling, namely the determination of the sample based oncertain criteria and based on the consideration of researchers. The results showed that 1) Theperception of the BLU is different - different. 2) Budget planning is already using the RBA asthe budget plan. 3) Source BLU reception from the state budget in the form of pure Rupiahand non-tax revenues came from students and other funding sources. 4) Has had threeaccounts that have been approved by theMinistry of finance. 5) The financial statements BLUconsist of the balance sheet, budget realization reports, activity reports, cash flow statementand notes to the financial statements and there are no clear technical guidelines on financialreporting BLU. 6) Have been prepared BLU performance accountability report. 7) Neverbefore have a budget deficit, and is still running a budget surplus. 8) Dewas still held byofficials not yet fully substitute god that can run all functions of a god .. 9) Monitoring offinancial management BLU implemented by SPI, Itjend, and the Office of PublicAccountants. 10) The remuneration system BLU yet fully implemented, the implementationof remun still follow the pattern of the ministries / agencies.
EFEKTIVITAS SERTIFIKASI DOSEN TERHADAP KOMPETENSI DOSEN DI POLTEKKES KEMENKES BENGKULU
Authors: Eliana Eliana
Published: January 2021

Performance is measured based lecturer faculty workload includes the followingprincipal activities of the learning plan, implement bembelajaran process, evaluating learning,guide and train, conduct research, perform community service and perform additional tasks.One of the government's efforts to improve the competence of lecturers, starting in 2008, noperformance assessment program called Lecturer Certification lecturers. The importance ofthe program Lecturer Certification as a form of assessment of faculty performance is expectedto improve the quality of education and provide benefits that can be perceived by students asoutput in the world of education. This study aims to determine differences in the competenceof lecturers who have tersertifkasi and yet tersertifkasi in Poltekkes MoH Bengkulu 2014.This research was analytic cross-sectional study. The population in this study are all still in thepolytechnic lecturers Bengkulu MoH both JFU and JFT are 85 people, samples were takenwith total sampling technique. Data analysis was performed using univariate and bivariateindependent T test. The results showed that the majority (75.7%) lecturers alreadytersertiifikasi, most (64.9%) lecturers are aged ≥ 45 years and almost all (83.8%) lecturershave been teaching ≥ 5 years, and there was no difference the competence of lecturers arecertified with certified faculty who have both pedagogical, professional, personal and social. Itis expected that the relevant agencies to carry out monitoring and evaluation of the learningprocess both on students and lecturers.
Rooting dynamics of Prunus minicuttings
Authors: Fiss Timm Cari Rejane , Schuch Márcia Wulff , Pinto Tomaz Zeni Fonseca , Casarin Josiane Vergara , Ramm Aline , Raasch Carlos Gustavo
Published: January 2021

There is a lot of information on the peach tree culture. However, it still lacks an efficient system for the seedlings production that guarantees genetic and sanitary quality, resulting in high productivity. The objective of this study was to determine the optimum rooting time for Prunus minicuttings to obtain clonal rootstocks. The installation of an experiment happened to check the viability of propagation by herbaceous minicuttings of the rootstocks, using Flordaguard, Okinawa, and the Capdeboscq canopy cultivar on different evaluation days (20, 30, 40, 50, and 60 days). Each treatment consisted of four replications of 20 minicuttings. The experiment consisted of preparing herbaceous minicuttings of approximately three to five centimeters, containing two buds and a leaf cut in half, with a bevel cut at the apex and transverse at the base of the mini-pile and two superficial lesions on opposite sides of the base. Later, they were immersed in a solution of 2000mg L-1 of indolebutyric acid (IBA) for 10 seconds and placed in transparent plastic containers containing medium-granulated vermiculite, previously moistened. Afterward, they were placed in greenhouses under controlled temperature. At 50 days, the highest percentage of rooting observed in the cultivar was Flordaguard (70%). The other cultivars resulted in a lower percentage of rooting on different evaluation days.
Desvios posturais, atividade física e puberdade: estudo transversal com crianças
Authors: Montenegro Cristianne Morgado , Tozo Tatiana Affornali , Pereira Beatriz Oliveira , Santos João Otací­lio Libardoni Dos
Published: January 2021

Introdução: Atualmente, os desvios posturais representam um dos maiores problemas epidemiológicos entre a comunidade infantojuvenil. Objetivo: Analisar se existe associação entre a aptidão aeróbia e o nível de atividade física em crianças e adolescentes e a ocorrência de desvios posturais em crianças e adolescentes. Métodos: O estudo analisou 380 crianças e adolescentes, sendo 54% do sexo feminino e 46% do sexo masculino, entre 10 e 18 anos idade. As variáveis selecionadas foram: Aptidão aeróbia, Nível de atividade física e Desvios posturais. Para determinar as variáveis foram utilizados: Fitnessgram, Questionário Internacional de Atividade Física, e o método de fotogrametria de Avaliação Postural Baseada em Imagem Digital versão 3.1. Resultados: Verificaram-se asssociações estatisticamente significativas entre a aptidão aeróbia e a hiperlordose lombar no sexo masculino (p = 0,049). A regressão logística binária ajustada para o grupo dos meninos (OR = 3,268) apresentou a possibilidade da hiperlordose lombar se desenvolver três vezes mais em meninos com aptidão aeróbia adequada. Conclusão: Meninos com hiperlordose lombar apresentaram níveis adequados de aptidão aeróbia. Outros fatores de risco, como a aptidão muscular parecem influenciar na ocorrência da hiperlordose lombar.
Índice de massa corporal aumentada: qual a influência sobre a força muscular ventilatória?
Authors: Silva Wasly Santana , Mestre William Santos , Silva Edvan Santos , Santos Junior Jailson de Souza , Viana David Eduardo Santos , Wagmacker Djeyne Silveira
Published: January 2021

Introdução: A força muscular ventilatória (FMV) e fatores anatômico/biológicos são importantes no funcionamento e manutenção da homeostasia corporal. Dessa maneira, é fundamental o estudo da mecânica respiratória e condições que podem alterá-las. Estudos apontam que a obesidade diminui a Pressão Inspiratória Máxima (PImáx) e Expiratória Máxima (PEmáx), no entanto, esses estudos são contraditórios em seus resultados. Objetivo: Verificar se existe diferença entre a FMV de indivíduos obesos e eutróficos. Métodos: Estudo observacional comparativo, no qual foram avaliados 40 indivíduos de ambos os sexos, divididos em dois grupos: 20 indivíduos com obesidade grau I e 20 indivíduos eutróficos. Foi considerada aumentada a circunferência abdominal (CA) >102 cm para homens e 88 cm para mulheres. Aplicado o teste t de Student não pareado bidirecional para comparação entre a Pressão Inspiratória Máxima (PImáx) e Pressão Expiratória Máxima (PEmáx) dos grupos avaliados. Utilizado o programa BioEstat 5.0 e adotado como significativo um p ˂ 0,05. Resultados: A média da PImáx para obesos e eutróficos foi respectivamente de 147 ± 73 vs 145 ± 70 cmH2O (p = 0,91). Para a PEmáx, a média do grupo obeso e eutrófico foram respectivamente de 133 ± 28 vs 135 ± 27 cmH2O (p = 0,93). Conclusão: Indivíduos sedentários com obesidade grau I associado ao aumento da circunferência abdominal não apresentam diferença na PImáx e PEmáx quando comparados a indivíduos eutróficos.
Lisura e credibilidade: termos irmanados da pesquisa científica
Authors: Petto Jefferson , Andrade Antônio Marcos , Do Sacramento Marvyn de Santana
Published: January 2021

Com aparecimento da pandemia da COVID-19, a ciência ganha um papel de protagonismo no cenário mundial. A comunidade científica se tornou ainda mais exigida para a apresentação de resultados em um curto espaço de tempo. Essa necessidade de performance, passa a ser usada como justificativa por alguns cientistas para negligenciar alguns pressupostos do método cientí-fico, colocando assim em risco a credibilidade cientifica. Contudo, infelizmen-te, esse questionamento não é uma novidade. Douglas Altman em seu editorial publicado pelo JAMA [1], já chamava atenção a respeito da baixa qualidade científica dos artigos publicados em revistas médicas. Atualmente, no campo científico, vivenciamos além de uma epidemia do vírus, uma epidemia de infor-mação, onde se produz em grande escala e alta velocidade, muitas vezes, sem atender o rigor metodológico adequado, fato que compromete a veracidade da informação, e contribui para um ecossistema cientifico defeituoso e, conse-quentemente, com baixa credibilidade...
El valor histórico de las haciendas Malqui-Machay y su incidencia en el aporte de la Identidad Cultural del Cantón La Maná
Authors: Toapanta Caizaluisa Peterson Arturo , Zambrano Cuadro Natalia Geoconda , Llore Chicaiza Wendy Sabrina , Calvopiña León César Enrique
Published: January 2021

Introducción. Las haciendas Malqui-Machay ubicadas en la parroquia de Guasaganda, cantón la Maná, posee vestigios arqueológicos mismos que se los conocen como la última morada del Inca Atahualpa por los sucesos históricos que han sido de importancia para la historia ecuatoriana ya que habría sido el refugio de los últimos Incas. Estos acontecimientos son un aporte para la identidad cultural del sector gracias a la historia que posee, Sin embargo, presenta debilidades en la conservación de la arqueología y con ello la identidad cultural de la población Lamanense, esto ha sido consecuencia de la devaluación de la infraestructura y por las condiciones climáticas. Objetivo.  Preservar el valor histórico de las haciendas Malqui-Machay y su incidencia en la identidad cultural del cantón La Maná. Metodología. Para la presente investigación se trabajó con una muestra de 69 personas en donde se tomó la opinión de profesionales, propietarios de las haciendas y la población de la parroquia de Guasaganda, esta información fue levantada a través de salidas de campo mediante las técnica de la entrevista (5) y encuesta (64),mismas que fueron formuladas con interrogantes estructuradas cerradas; El propósito principal fue recabar información para conocer el criterio y el conocimiento de los pobladores acerca de los hitos históricos que sucedieron en las haciendas Malqui-Machay. Resultados. Según el estudio de la identidad cultural realizado en las haciendas Malqui-Machay se enmarcan importantes resultados ya que estos sitios fortalecen las costumbres y tradiciones de la población gracias a los acontecimientos de cada hacienda y las leyendas existentes en la zona circundante. Con estos datos positivos se procede a realizar el diseño de una guía informativa de patrimonio cultural la cual contenga tres secciones: informativa, leyendas y conservación. Con el propósito fundamental de rescatar parte de la identidad cultural de los habitantes del cantón La Maná. Conclusión. Dentro de las haciendas Malqui-Machay existe un gran potencial turístico cultural el cual aporta en la identidad cultural de los habitantes de la parroquia Guasaganda Cantón La Maná ya que se encuentra una arqueología que se desarrollaron gracias, a los acontecimientos y a la memoria histórica que se han evidenciado en dicho lugar y a las leyendas que han prevalecido en el tiempo y que son un icono para el sector.
Incidencia de las metodologías de enseñanza en las carreras de ciencias administrativas ofertadas por las universidades públicas del DMQ.
Authors: Herrera Enríquez Giovanni , Castillo Páez Sergio , Zambrano Vera Danny , Herrera Sánchez Maybelline Jacqueline , Casanova Villalba César Iván
Published: January 2021

Introducción: La difusión del conocimiento forma parte de la evolución y el desarrollo humano, en este espacio la educación superior juega un papel primordial en la búsqueda, difusión y construcción del conocimiento. se han desarrollado varios métodos de enseñanza para permitir a los estudiantes asimilen el aprendizaje. Objetivo: Determinar la efectividad de los diversos métodos de enseñanza impartidos por los docentes a los estudiantes en nivel de pregrado, focalizando la perspectiva del estudiante sobre los métodos aplicados por sus docentes y la concepción del aprendizaje. Metodología: esta investigación es de tipo teórica basada en documentos, con la utilización de herramientas como la aplicación de encuestas, dando un resultado descriptivo exploratorio, aplicando un método deductivo analítico. Resultados: los métodos más aplicados por los docentes son conferencias magistrales y el aprendizaje basado en problemas, sin embargo, los métodos de estudios de caso y simulaciones son calificados por los estudiantes como los que brindan mejores resultados para la captación del aprendizaje. Conclusión: Se analizó los resultados de la investigación  a los estudiantes del último año de las carreras de Administración de Empresas, Contabilidad y Auditoría de la Universidad Central del Ecuador y de la Universidad de las Fuerzas Armadas ESPE, y se tienen dos conclusiones de trascendencia, la primera que los estudiantes no tienen una correcta interpretación de cada concepto de los diferentes métodos por ende no conciben la diferencia entre su aplicación, la segunda es que los docentes no buscan nuevas formas de llegar a los estudiantes y se encasillan en los métodos típicos, por tal motivo no existe una diferencia de circunstancial en conocimientos.
Training Programme on Applied Research Methodology and SPSS
Authors: Lasker Shamima Parvin
Published: January 2021

Bangladesh Bioethics Society in cooperation with National Institute of Neuro Science (NINS), Agargoan, Dhaka is going to organized 60 hours (Two weeks) Training Course on Applied Research Methodology and SPSS on February, 2021 for the Post graduate Medical Students of NINS. The course is designed to familiarize the participants with modern tools, techniques and methodologies of research to develop professional knowledge and skills in the field of Health care system. After completion of the course, participants will be expected to undertake research projects independently and to be able to evaluate the research progress at each stage of the process.

This programme is funded by SSRC, Planning Division, Ministry of Planning, Government of the People’s Republic of Bangladesh
Synthesis, Characterization and In-Silico Analysis of New 2-Pyrazolines
Authors: Saroja T. , Ezhilarasi R. M. , Selvamani V. , Mahalakshmi S.
Published: January 2021

Heterocyclic compounds such as pyrazolines, pyrimidines, oxazole and isoxazole exhibit different pharmacological activities. The current study involves synthesis of new 2-pyrazolines. The synthesis involves the cyclocondensation reaction of substituted chalcones with (4-fluorophenylthio)acetic acid hydrazide (FTAH) under reflux. The chalcones (C1-C7 / 1a-1g) were synthesized from the reaction of substituted acetophenone with substituted benzaldehyde and FTAH was prepared from 4-fluro thiophenol. New 2-pyrazolines were obtained in good yields (60-70 %). All the compounds were characterized by FT-IR, 1H, 13C NMR and mass spectra. PASS analysis was carried out for the 2-pyrazolines synthesized (P1-P7 / 3a-3g).
Effect of Deposition Time on Structural and Optoelectronic Properties of Flower-Like Nanostructured PbS Thin Films
Authors: Sheeba N. H. , Namitha A. , Ramsiya K. M. , Ashitha T. M. , Suhail R.
Published: January 2021

Polycrystalline nanostructured PbS thin ﬁlms are deposited onto soda-lime glass substrates by the method of chemical bath deposition (CBD) at different duration of deposition time. The structure and surface morphology of the ﬁlms are characterized by X-ray diﬀraction (XRD) and field effect scanning electron microscopy (FE-SEM). XRD pattern exhibits polycrystalline structure with preferential orientation along (200) direction, parameters such as crystallite size, lattice constant, lattice-strain and dislocation density are calculated. The FE-SEM images show appearance of flower like structure on formation of PbS films which is indicative of suitability in gas sensing applications. Studies on optical properties carried out by UV-Vis spectroscopy measurements show bandgap in the range 1.65eV – 1.41eV. The photoluminescence spectra of the films exhibit two peaks centered at around 613 nm and 738 nm after excitation at 450 nm. Electrical studies from Hall measurements indicate the carrier concentration and mobility of the PbS samples corroborate the variations in the conductivity.
Comparative Antimicrobial Study of Different Parts of Ocimum americanum L., O. basilicum L. and O. sanctum L. in Comparison to Standard Antibiotics Collected from Dibrugarh, Assam
Authors: Chetia J. , Saikia L. R. , Upadhyaya S. , Khatiwora E. , Bawri A.
Published: January 2021

Lamiaceae members are commonly used in ethno-medicinal practices of our country. The in vitro antibacterial and antifungal activity of various solvents extracts of different aerial parts of Ocimum americanum L., O. basilicum L. and O. sanctum L. wereassessed on standard bacterial and fungal strains using standard laboratory methods. Extracts from O. americanum have inhibitory activity against B. subtilis, B. cereus and S. aureus.Acetone extracts of O. basilicum and O. sanctum were found to be more potent being capable of exerting significant inhibitory activities against majority of the bacteria investigated. Acetone extract of young inflorescence of O. americanum showed highest antibacterial activity against B. cereus (14±1mm) which was also higher (10±1mm) than the inhibition of standard Clotrimazole (10mcg). Hot petroleum ether extract of mature leaves of O. basilicum showed highest activity against E. coli (16±2mm) which was also higher than the inhibition ofAmpicillin, Streptomycitin, Erythromycin.Petroleum ether extract of young leaves of O. sanctum recorded highest inhibition against P. vulgaris (20±2mm). Presence of tannins, flavonoids, saponins, phenols in all the parts of the plants. Use of different parts instead of using whole plant will help in sustainable management of these medicinal plants.
Phonon Dynamics and Acoustic and Thermodynamic Properties of Pt57.5Cu14.7Ni5.3P22.5 Bulk Metallic Glass
Authors: Koireng R. R. , Agarwal P. C. , Gokhroo A.
Published: January 2021

The phonon dispersion curves for Pt57.5Cu14.7Ni5.3P22.5 bulk metallic glass (BMG) are computed employing various dielectric screenings using the simple model given by Bhatia and Singh. The force constants β and δ for computing the dispersion curves are calculated from the elastic constants i.e. bulk modulus (B) and shear modulus (G) along with the calculated value of force constant κe of the material of the glass for the first time. The results of the phonon dispersion curves show appropriate behavior in the long wavelength region in detail for both the longitudinal and transverse modes and give insight regarding the acoustic and thermal properties of the BMG. The transverse sound velocity and the longitudinal velocities with various dielectric screening are calculated from the dispersion curves in the long wavelength region. The corresponding thermodynamic property (Debye temperature) is calculated for different dielectric screenings. The theoretical results predicted are in a good agreement with the reported data in the literature for the Pt57.5Cu14.7Ni5.3P22.5 BMG and may be used for correlating other properties.
A Reliable Computational Algorithm for Solving Fractional Biological Population Model
Authors: Devi A. , Jakhar M.
Published: January 2021

In this work, authors obtained the series solution of nonlinear fractional partial differential equations, which is emerging in a spatial diffusion of biological population model using Elzaki transform homotopy perturbation method (ETHPM). The Elzaki transform homotopy perturbation method is a combined form of the Elzaki transform and homotopy perturbation method. Three test illustrations are used to show the proficiency and accuracy of the projected method. It has been observed that the proposed technique can be widely employed to examine other real world problems. The results obtained with the help of the proposed technique are plotted for different fractional orders.
Glucopyranoside Dipentanoyl Esters: Synthesis, PASS Predication, Antimicrobial and In Silico ADMET Studies
Authors: Matin M. M. , Chowdhury S. A. , Bhuiyan M. M. H. , Kawsar S. M. A. , Alam M. A.
Published: January 2021

Dimolar pentanoylation of methyl α-D-glucopyranoside using direct method furnished the 2,6-di-O-pentanoate indicating regioselectivity at C-6 and C-2 positions. To develop glucopyranoside based potential antimicrobial agents, 2,6-di-O-pentanoate was further converted into eight newer 3,4-di-O-acyl esters reasonably in good yields. Both prediction of activity spectra for substances (PASS) and in vitro antimicrobial activity test established them as better antifungals than antibacterials. PASS predication also indicated that these sugar esters (SEs) are more potent as anticarcinogenic agents than as antioxidant agents. Structure activity relationship along with in silico ADMET studies clearly indicated that combination of pentanoyl (C5) and lauroyl (C12) in the glucopyranoside framework could be a potential antifungal agent especially against Macrophomina phaseolina.
Enhancement of Electrical Conductivity of Polyaniline Synthesized by using Carbon Nanofiber
Authors: Rahman M. M. , Sarker D. R. , Rahman M. M. , Faruk M. O.
Published: January 2021

Carbon nanofiber (CNF) is a very useful additive for improving the performance of polymer matrix composites, but the performance has sometimes been interrupted by limits appear within composite processing. Recently, CNF based polymer composites are intensely considered as promising materials in many application fields, such as electrical devices, electrode materials for batteries, supercapacitors, sensors, etc. Among these, the electrical conductivity is always the first priority need to be considered. Polyaniline (PANI) and PANI-CNF composites are synthesized by chemical oxidative polymerization of aniline monomers in acidic media. The electrical conductivity of PANI-CNF composites were found varies with the degree of amount of CNF under the effect of multiple factors such as the concentration of aniline monomer, reaction media, oxidant, reaction temperature, reaction time, etc. The maximum electrical conductivity was found 3.7131 S/cm of the PANI-CNF composite coming from the polymerization of aniline with 0.05 g CNF. The results of the synthesis also demonstrated that CNF can be an effective material to prepare electrically conducting polymer composites with ordered nanostructures.
Non-covalent Interactions Directed Rearrangement of Lactones to Pyrones: A Computational Study on the Mechanistic Insights of Solvent Assisted Gold(I) Catalyzed Reactions
Authors: Gayatri G.
Published: January 2021

The mechanism of gold(I) catalyzed cycloisomerization of lactones to pyrones was analyzed by performing DFT study using B3LYP method with LanL2DZ basis set for Au and 6-31g(d) basis set for all other atoms. The potential energy surface of the reaction was scanned to know the preferred path for the formation of products under gas phase. The effects of solvent using acetonitrile, dichloromethane and toluene are explored as these solvents are reported to play a crucial role in the final product formation. The crossover between the oxophilic and alkynophilic reaction complexes, R-O and R-C, is found to be the major driving force which directs the product formation. While the larger energy gap between R-O and R-C leads to pyrone formation, the smaller difference and in turn the rapid crossover between R-O and R-C leads to the formation of decarboxylation adduct. Counterion plays a major role throughout the reaction. The atoms in molecules analysis on R-C using implicit as well as explicit solvent gave reason for the observed experimental trends and suggest that the prevailed non-covalent interactions play a substantial role in the product formation.
Restrained Edge Domination Number of Some Path Related Graphs
Authors: Vaidya S. K. , Ajani P. D.
Published: January 2021

For a graph G = (V,E), a set  S ⊆ V(S ⊆ E) is a restrained dominating (restrained edge dominating) set if every vertex (edge) not in S is adjacent (incident) to a vertex (edge) in S and to a vertex (edge) in V - S(E-S). The minimum cardinality of a restrained dominating (restrained edge dominating) set of G is called restrained domination (restrained edge domination) number of G, denoted by  γr (G) (γre(G). The restrained edge domination number of some standard graphs are already investigated while in this paper the restrained edge domination number like degree splitting, switching,  square and middle graph obtained from path.
Media Optimization for Production of Recombinant Carrier Protein (CRM197) in Escherichia coli
Authors: Shukla S. , Mishra D.
Published: January 2021

Since the advent of vaccines, the mankind has benefited from the same and has been able to curb the mortality rate around the globe. Amongst different types of available vaccines, polysaccharide based vaccines are very widely used against various infectious diseases. The polysaccharide vaccines need to be conjugated with a carrier protein to make the vaccine more immunogenic. Recombinant Escherichia coli cells are the organism of choice for large scale production of a carrier protein because of its widely studied scientific aspects. In the present study, for proof of concept, the recombinant E. coli cells were cultured in Luria-Bertani media to check the expression of rCRM197. At 80L scale, it was observed that when recombinant E. coli cells were grown in a chemically defined media, it resulted in inconsistent growth and a long lag phase. When the defined media was supplemented with yeast extract, the lag phase of the culture was substantially reduced and the maximum growth of the culture was achieved. Protein expression was checked using SDS PAGE (Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis) and Western blot technique. The optimized media resulted in a robust fermentation process to achieve high cell density and maximum biomass for the production of recombinant protein.
Perubahan Perilaku Kelompok Bandeng C73 Melalui Pemanfaatan Tulang Ikan Bandeng (Chanos chanos) di Kecamatan Tirtajaya Karawang Jawa Barat
Authors: Hernawati Ena , Supenti Lilis , Hanan Abdul
Published: January 2021

Penelitian ini bertujuan mempelajari perubahan perilaku Kelompok Bandeng C73 berupa pengetahuan, sikap dan keterampilan masyarakat tentang pemanfaatan tulang ikan bandeng melalui kegiatan penyuluhan. Penelitian dilakukan di Kecamatan Tirtajaya Kabupaten Karawang Provinsi Jawa Barat pada tanggal 2 Maret hingga 15 Mei 2020. Penyuluhan dilakukan menggunakan metode demonstrasi cara, ceramah dan diskusi. Aspek yang dievaluasi yaitu teknis, bisnis dan penyuluhan. Media yang digunakan dalam kegiatan penyuluhan yaitu media cetak berupa leaflet dan folder. Evaluasi penyuluhan dilakukan dengan membandingkan hasil pre test dan post test menggunakan kuesioner. Hasil penelitian menunjukkan bahwa perubahan perilaku masyarakat terhadap pemanfaatan limbah yaitu 76%. dalam segi lingkungan sasaran bisa mengurangi dampak pencemaran lingkungan udara (bau), air (dibuang di irigasi), tanah (dibuang secara sembarangan). Hasil analisa ekonomi menunjukkan pemanfaatan limbah menguntung kan dalam satu kali produksi pembuatan tepung tulang menghasilkan keuntungan Rp.91.000.- dan jika tepung tersebut diolah kembali menjadi kerupuk tulang ikan, stik tulang ikan atau diversifikasi olahan lainnya maka akan menghasilkan keuntungan yang lebih tinggi. Pemanfaatan tulang ikan bandeng bukan hanya mengubah perilaku sasaran menjaga lingkungan tetapi juga memberi keuntungan dalam segi ekonomi.
O papel do agente comunitário de saúde na disseminação de informações acerca dos principais cânceres de interesse na atenção básica
Authors: Silva Alex Luiz Menezes da , Silva Weydder Tavares da , Teixeira Eliel Barbosa , Khayat André Salim , Rodrigues Thaíssa Vitória Portal , Khayat Bruna Cláudia Meireles
Published: January 2021

Este trabalho tem por objetivo avaliar os conhecimentos prévios dos agentes comunitários de saúde (ACS) atuantes em Belém do Pará sobre os principais tipos de câncer na atenção básica (AB). Para isso, desenvolveu-se uma pesquisa transversal, descritiva, em que participaram 66 ACS, de seis unidades de saúde da família do distrito administrativo do Guamá. A fim de avaliar os conhecimentos, aplicou-se um questionário com questões objetivas abordando os eixos: socioeconômicos e demográficos dos participantes; conhecimentos prévios sobre a fisiopatologia do câncer; prevenção e fatores de riscos dos principais cânceres na AB e níveis de organização de Atenção em Oncologia. Entre os resultados, constatou-se que a maioria dos pesquisados conheciam a fisiopatologia, assim como a definição correta de metástase (87,88%). Sobre o aspecto de prevenção do câncer, 95,45% apontaram medidas ou fatores de riscos que estão relacionados ao desenvolvimento da doença. Contudo, poucos distinguiam os níveis da atenção especializada em oncologia e suas atribuições; assim como a periodicidade e faixa etária envolvida nos rastreios do câncer de mama (27,27%) e colo de útero (30,30%), ou seja, apenas uma minoria afirmou conhecer a conduta adequada para rastreio do câncer de mama e colo do útero de acordo com o Ministério da Saúde. Além disso, ter familiar com câncer apresentou relevância estatística quanto ao número de assertivas corretas (p<0,05). Conclui-se que, possivelmente, existam deficiências no conhecimento dos ACS sobre tal temática, com percentual de acerto maior nos que tiveram parentes acometidos com algum tipo de câncer.
Conhecimento dos cirurgiões-dentistas sobre atendimento odontológico em gestantes
Authors: Cardoso Lucas Santana , Costa Bianca Maria de Melo , Silva Maísa Sales Oliveira e , Pessoa Tayná Marques , Costa Bianne Maria de Melo , Trinta Roberta Remiliana Silva
Published: January 2021

Na cavidade bucal a cárie, gengivite e a periodontite são comumentes agravos encontrados em mulheres grávidas, precisando serem tratadas. No entanto, os cuidados com o atendimento a esse público requer muita atenção sendo resultado de muitas dúvidas de cirurgiões-dentistas. Logo, o objetivo desse estudo é descrever sobre o atendimento à gestantes na Odontologia, reunindo protocolos e avaliando se o conhecimento dos cirurgiões-dentistas são suficientes para realizar um atendimento seguro para a gestante e para o bebê. Para isso, foi realizada uma revisão narrativa da literatura que utilizou como descritores: gestantes, odontologia e odontopediatria. Foram utilizados artigos, monografias e dissertações nas bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), BBO (Bibliografia Brasileira de Odontologia), MEDLINE (National Library of Medicine) e Google Acadêmico, sendo selecionados os artigos primariamente pelo título e resumo e depois, de modo mais específico, atendendo aos critérios de inclusão e exclusão. Através da revisão pode se afirmar que as gestantes devem ter prioridade nos programas de atenção odontológica, e os cirurgiões-dentistas devem procurar desmistificar mitos e crenças em torno do atendimento. A maioria dos estudos mostrou que, apesar de muitos profissionais afirmarem sentirem-se seguros, isso não garantiu que alguns cirurgiões-dentistas respondessem corretamente alguns questionamentos. Portanto, é necessário que cada vez mais esses profissionais tornem-se aptos a prestarem esse serviço, seja através da elaboração de protocolos ou que as instituições de ensino superior abordem esse conteúdo de forma mais intensiva, pois o tratamento a gestante jamais deve ser negligenciado.
Avaliação toxicológica: alterações em biomarcadores desencadeadas por exposição de trabalhadores rurais a agrotóxicos
Authors: Porto Murilo de Jesus , Souza Jaciara Pinheiro de , Costa Emile Ivana Fernandes Santos , Oliveira Cinara Rejane Viana , Guerra Maria de Fátima Santana de Souza , Araujo Ana Mara Borges , Souza Jeferson de Menezes
Published: January 2021

Os agrotóxicos ou pesticidas são considerados substâncias quimícas que agem no meio ambiente, no sentido de controlar diferentes elementos que prejudicam o cultivo das lavouras ou pastagens, geralmente, sendo utilizados por trabalhadores ocupacionais a nível rural no intuito de maior produção e erradicação de doenças e pragas exitentes. Muitos trabalhadores não sabem lidar corretamente com a aplicação, compra, diluição e descarte dos agroquímicos. Dessa maneira, esta pesquisa tem como objetivo discutir as principais alterações em biomarcadores desencadeadas por exposição de trabalhadores rurais a agrotóxicos. Como metodologia o presente estudo trata-se de revisão narrativa, realizada entre os meses de agosto e dezembro de 2020. O levantamento de dados não se pautou para restrição do ano de publicação dos estudos encontrados. As bases de dados utilizadas foram: National Center for Biotechnology Information (PUBMED); Scientific Electronic Library Online (SCIELO); Literatura Latino- Americana e do Caribe em Ciências da Saúde (LILACS); sites confiáveis; livros. A presente pesquisa mostra que o monitoramento de biomarcadores de exposição a agrotóxicos pode ser útil para verificar o surgimento de disfunções fisiológicas em populações expostas. Ressalta-se que os biomarcadores mais utilizados para a avaliação dos trabalhadores expostos aos agrotóxicos seriam as enzimas acetilcolinesterase eritrocitária (AChE) e butirilcolinesterase (BuChE), assim com o processo de exposição a agrotóxicos desencadea uma série de reações fisiológicas a nível nervoso, diminuindo, principalmente, a ação da enzima acetilcolinesterase, essa que por sua vez é responsável pela quebra do excesso da acetilcolina.
Stable isotopes in seabirds reflect changes in marine productivity patterns
Authors: Ramírez F , Vicente-Sastre D , Afán I , Igual JM , Oro D , Forero MG
Published: January 2021

Seabirds have been proposed as suitable candidates for tracking and monitoring changes in marine systems (bioindicators). However, their suitability depends on our ability to link the large degree of environmental variability inherent to marine systems with a few, relevant, and accessible signals (biomarkers) informing on changes in their feeding behavior or reproductive performance. We combined satellite remote-sensing records with stable isotope data (δ15N and δ13C) and breeding parameters (fledging success) spanning several years (2001-2014) to investigate the ecological responses to environmental variability by 2 sympatric seabirds inhabiting the western Mediterranean: Scopoli’s shearwater Calonectris diomedea and Cory’s shearwater C. borealis. Both species showed similar annual variations in their stable isotopic composition, likely as a response to the trophic consequences of changes in the magnitude and timing of the annual peak in marine productivity (as proxied by satellite imagery of chlorophyll a concentrations). In contrast, no relevant responses were observed in their breeding performance, suggesting that their life-history strategy has evolved to constancy in breeding success, which diminishes its value as a biomarker of changes in marine productivity patterns. Despite this limitation, combining remote sensing and stable isotopes in seabirds is a reliable and powerful tool for the early detection of fine-scale, climate-driven changes in marine productivity patterns and its cascading effects across communities and trophic levels, especially under the current scenario of ocean warming.
Biological correlates of sea urchin recruitment in kelp forest and urchin barren habitats
Authors: Weitzman B , Konar B
Published: January 2021

Shifts between the alternate stable states of sea urchin barren grounds and kelp forests correspond to sea urchin density. In the Aleutian Archipelago, green sea urchins Strongylocentrotus polyacanthus are the dominant herbivores that graze kelp forests. Sea urchin recruitment is an important driver that influences sea urchin density, particularly in the absence of top-down control from a keystone predator such as the sea otter Enhydra lutris. To understand how the biological community may influence patterns of sea urchin recruitment, we compared sea urchin recruit (size ≤20 mm) densities with biomass of other benthic organisms in both barren ground and kelp forest habitats at 9 islands across the Aleutian Archipelago. Patterns of biological community structure between the 2 habitats did not explain patterns of sea urchin recruits; however, the same 10 specific taxa were found to correlate with sea urchin recruits in each habitat. Taxa that showed strong positive correlations included Codium, Constantinea, Schizymenia, and hydrozoans, while strong negative correlations were observed with Pachyarthron and Pugettia. Weak positive correlations were observed with Alcyonidium and ascidiaceans in both habitats, while weak variable relationships were detected with Polysiphonia and Corallina between habitats. The observed species-specific relationships may be due to small sea urchin displacement by larger conspecifics, larval responses to settlement cues, post-settlement survival via biogenic refugia, or potentially predation. These potential species-specific interactions were apparent, regardless of habitat, and it can be inferred that they would be preserved in the presence or absence of keystone predation.
Ritmuszavarok hypertoniában
Authors: Zámolyi Károly
Published: January 2021

A hypertonia a cardiovascularis betegségek – szívelégtelenség, coronariabetegség, stroke és krónikus veseelégtelenség – fő és leggyakoribb rizikófaktora. A hypertoniás szívbetegség egyik klinikai manifesztációja a különböző ritmuszavarok megjelenése, amely a myocardium strukturális és funkcionális patofiziológiai változásával magyarázható. Hypertoniában a leggyakoribb ritmuszavar a pitvarfibrilláció, de más supraventricularis és kamrai arrhythmiák is előfordulnak főleg balkamra-hypertrophia vagy szívelégtelenség esetén.
Az angiotenzinreceptor-neprilysin inhibitor (ARNI) kezelés eredményessége a szívelégtelenség kezelésében. 2020 ARNI, VIDI, VICI…
Authors: Várallyay Zoltán
Published: January 2021

Az ARNI- (valzartán/szakubitril) terápia egy új típusú hatástani csoport tagjaként számos klinikai evidenciával rendelkezik a szívelégtelenség szinte teljes spektrumában, különösen csökkent balkamra-funkció és társult hypertonia esetén. Bemutatjuk az ARNI-kezeléssel foglalkozó, legfontosabb és megfelelő evidenciával rendelkező alapvető tanulmányokat és a kezelés eredményességét szívelégtelenségben. A vizsgálatok kedvező eredményei alapján a szakmai irányelvekben egyre meghatározóbb ajánlásként jelenik meg indikációja. Alkalmazása a mindennapi klinikai gyakorlatban hatékony, biztonságos terápiás segítséget jelent az ismerten rossz prognózissal bíró szívelégtelen betegek számára. A szer már hazánkban is elérhetővé vált.
Magyarország Átfogó Egészségvédelmi Szűrőprogramjának (MÁESZ) hypertonia vonatkozásai – első 10 év
Authors: Barna István , Kékes Ede , Daiki Tennó , Dankovics Gergely
Published: January 2021

A szűrővizsgálatok a háziorvosi gyakorlatban ismertek, ugyanakkor nagy jelentőségű a vizsgálóhelyektől távol élő lakosság számára a szűrések elérhetősége és ennek során a nyerhető információ megismerése. Magyarországon és a világon is egyedülálló kezdeményezés a Magyarország Átfogó Egészségvédelmi Szűrőprogramja 2010–2020. Hazánk legnagyobb, humanitárius formában működő egészségvédelmi programja, amely a lakosság számára ingyenesen biztosítja a szűrővizsgálatok elvégzését a legmodernebb eszközökkel, szem előtt tartva a megelőzés fontosságát. A program 76 szakmai szervezet összefogásával, európai uniós irányelvek alapján a Magyar Orvostársaságok és Egyesületek Szövetsége (MOTESZ) által koordinált szív- és érrendszeri betegségek megelőzésének és gyógyításának nemzeti programjával, konszenzusos együttműködésével valósul meg (1–6). Jelen közleményünkben a 2010–2019 közötti időszak hypertoniával összefüggő adatait mutatjuk be.
Enfermedad de Coronavirus 2019 (COVID-19). Primera parte
Authors: Valdivieso-Rodriguez Manuel
Published: January 2021

Se presentan varios artículos preparados por distinguidos médicos peruanos radicados en los EEUU en relación a la pandemia mundial del Coronavirus 2019 (COVID-19). Los artículos están basados en presentaciones efectuadas por estos científicos como parte del programa educativo de la XLVII Convención Anual de la Peruvian American Medical Society (PAMS), que este año se efectuó en forma virtual debido a que la pandemia nos imposibilitó hacerlo en forma presencial en Arequipa, Perú.  Las presentaciones virtuales ocurrieron los días 17 y 18 de setiembre, 2020 y fueron realizadas vía Zoom.  Estas conferencias virtuales, cortas y precisas, fueron posibles por el coauspicio de la PAMS, la Universidad Peruana Cayetano Heredia de Lima y la Universidad Católica de Santa María de Arequipa.