bluuebunny/crossref_metadata_2025 huggingface dataset:
ON THE QUESTION OF THE FORMATION OF ETHNIC IDENTITY
Authors:   Saint Petersburg University of Humanities and Social Sciences, Smolina T.L.
Published: January 2023

The increase of ethnic activities in a contemporary world is connected with the phenomenon of ethnic identity. This article is dedicated to the topical theme of the development of ethnic identity. The purpose of this work is the analysis of the stages of the formation of ethnic identity. Ethnic identity is regarded as a part of social identity as well as a process of awareness of the belonging to a particular ethnic group. This article examines domestic and foreign classifications of the formation of ethnic identity. In the current work cross-cultural studies connected to the differences in ethnic belonging at different age periods are examined. The present paper addresses ethnic perceptions, ethnodifferentiating traits as well as the main socialization agents that influence the development of ethnic identity in each individual age period. The methodological difficulties that researchers face in studying the formation of ethnic identity are indicated. The results of the study of the formation of ethnic identity on the example of the biographical method “Ethnic autobiography” are considered. Four stages of ethnic identity formation are highlighted: preschool age, primary school age, adolescence, youth age. In preschool age ethnic perceptions are characterized by instability and socialization agents such as family and preschool institutions play a significant role. In the primary school age school and peers play an important role in the development of ethnic identity. This period is characterized by the diffusiveness of ideas about one's own ethnic identity. In adolescence affective component of identity prevails over the other components. This stage is characterized by a deeper understanding of one’s ethnicity, the commonality of historical fate and religion. Awareness of ethnic identity based on ethnodifferentiating traits occurs in adolescence and considered as most stable compared to previous age periods. This age is characterized by the most complete system of self-awareness as a member of the ethnic community. The process of ethnic identity formation does not end in youth due to the fact that questions about ethnicity can be raised at other stages of a person's life path.
THE YOUTH OF RUSSIA: CREATING THE FUTURE MOVEMENT AS AN INNOVATIVE FORM OF THE YOUTH OLYMPIAD MOVEMENT IN THE RUSSIAN FEDERATION
Authors:   M. Akmulla Bashkir State Pedagogical University, Galimova Kh.Kh. , Iksanova R.M. ,   M. Akmulla Bashkir State Pedagogical University, Aitov V.F. ,   M. Akmulla Bashkir State Pedagogical University
Published: January 2023

The article substantiates the relevance of creating conditions for the education of representatives of modern youth of a new type with universal competencies, organizational, leadership qualities that are able to think creatively, and productively solve practical problems. In the process of the accelerated pace of society, the expansion of intercultural boundaries, the exchange of information, and the renewal of knowledge, there is a need to change targets in the formation of a generation of young people. Representatives of modern youth should be ready to effectively solve communicative problems in the framework of innovative projects implementation, determine their personal growth points, flexibly adapt to new challenges of the economy, production and social life of the country. The solution to this issue involves a new approach to the training of both students of secondary educational organizations and future teachers. This determines a change in the trajectory aimed at updating educational standards, which is generally focused on the formation of universal and professional competencies in demand by modern society when working with talented youth. New trends are reflected in state documents, the development of a set of measures for their implementation is underway, the National Coordinating Council for the Support of Young Talents of Russia has been created. The authors analyze the domestic experience in identifying and developing the abilities of learning youth in various subject areas and highly specialized areas. In particular, the article gives an analysis of the youth movements of the social, educational and artistic orientation. The results of a long -term study of the search for various forms of activity, focused on identifying gifted youth, will cause undoubted interest. As one of the ways to achieve the goal, the authors see in the organization of the Cup “Youth of Russia: Creating the Future”. A series of events within the framework of the Cup acts as one of the new promising forms of the Olympiad movement among schoolchildren, which involves the formation of universal and professional competencies in demand in modern society.
CREATIVE ACTIVITY OF UNIVERSITY STUDENTS AS A MEANS OF COMPREHENSIVE PERSONAL DEVELOPMENT IN THE CONDITIONS OF DIGITAL LEARNING
Authors:   Orel State Institute of Culture, Solntsev M.N.
Published: January 2023

The mechanisms of the organization of creative activity of university students, providing comprehensive personal development in the conditions of digital learning, are investigated. Digital learning is seen as a comprehensive system of learning that affects all key aspects of the educational process of higher educational institutions. The aims of students’ creative activity considered as one of the means of all-round development of personality are stated. The methodological basis for planning and organizing students’ creative activity under the guidance of a teacher is presented. The directions of students’ creative activity and its step-by-step organization are described. The principles of digital learning organization of students’ creative activities, in the implementation of which, the educational context of the studied disciplines is filled with practice-oriented professional content, are disclosed. This is achieved by integrating traditional teaching methods and the introduction of active, interactive methods, educational cases in teaching disciplines. Attention is paid to the structure of human abilities, which must be taken into account by the teacher, when organizing the creative activities of students. The scientific novelty of the article is to justify the use of creative activity as a means of comprehensive development of university students in the context of digital learning. As a result, it is concluded that teachers need to explore the possibilities of digital learning, in which the creative activity of students and their all-round development takes place. The article is of interest to teachers of universities, department methodologists, graduate students, organizers of additional education.
Safety and efficacy of favipiravir in COVID-19: a comprehensive literature review
Authors: Ahusayni Khalid , Alharthi Salman , Alhazmi Mona , Alaithan Shaima , Alotaibi Yasir , Alhaddad Zahra , Alrowaished Alhanuf , Almousa Hissah , Hakami Abdulaziz , Alotaibi Yasmin
Published: January 2023

The severe acute respiratory syndrome coronavirus 2 virus spread fast around the globe. The medical community is actively searching for an antiviral that could be effective against it. An antiviral drug called favipiravir, created for the treatment of influenza, may work well for coronavirus disease 2019 (COVID-19). Therefore, this study evaluated the safety and efficacy of favipiravir in COVID-19 by reviewing published articles. We found favipiravir is effective, safe, and tolerated against COVID-19. More information is needed to determine long-term consequences, such as QT prolongation, hyperuricemia, and teratogenicity. Favipiravir interacts with other medications such as repaglinide, pyrazinamide, theophylline, acyclovir, warfarin, and methotrexate. Physicians should be aware when prescribing it.
Corporate Tax Policy: Impact Tunnelling Incentive, Debt Covenant, And Transfer Pricing
Authors: Deden Tarmidi  , Agustin Fadjarenie  , Lin Oktris
Published: January 2023

Transfer pricing is considered one of the corporate policies for minimizing the tax burden. This study aims to analyze the role of transfer pricing in the influence of tunnelling incentives and debt covenants on corporate tax policy. Manufacturing companies listed on the Indonesia Stock Exchange are unit analyses in this study. Their 398-panel data after purposive sampling. Using STATA, this study found that tunnelling incentives are used in transfer pricing activities, while debt covenant and transfer pricing are used in management in tax policies. Meanwhile, debt covenant is not widely used in the transfer pricing scheme, and tunnelling incentive also does not affect management on corporate tax policy. The mediating role of transfer pricing is not found in the indirect effect of tunnelling incentives and debt covenants on corporate tax policy. This result explains that transfer pricing and debt covenants are commonly used by companies in their tax policy.
Jakość kształcenia wyższego w warunkach wojennych: wskaźniki i perspektywy badań
Authors: Nechytaylo Iryna
Published: January 2023

Artykuł jest poświęcony problemowi zapewnienia jakości szkolnictwa wyższego w warunkach wojny. Celem artykułu jest identyfikacja wskaźników jakości szkolnictwa wyższego oraz określenie perspektyw socjologicznych badań jakości szkolnictwa wyższego z wykorzystaniem tych wskaźników. Wyniki ankiety internetowej przeprowadzonej przez „Info Sapiens” na zlecenie Szkoły Analityki Politycznej Uniwersytetu Narodowego „Akademia Kijowsko-Mohylańska” ujawniają mocne i słabe strony zapewniania jakości szkolnictwa wyższego w Ukrainie podczas konfliktu zbrojnego, który rozpoczął się w lutym 2022 roku. Odnotowuje się utratę motywacji studentów, spadek wymagań profesorów, brak spersonalizowanej komunikacji profesor–student oraz brak zrozumienia przez studentów wagi i konieczności takiej komunikacji, które zdaniem autorki są pewnymi wyznacznikami spadku tejże jakości.
Welfare Improvement Models and Strategies through Dissemination of Family Planning Information in the Remote Indigenous Community of Baduy
Authors: Sihabudin Ahmad , Dimyati Idi , Tobing Melati Mediana
Published: January 2023

There are many types of  contraceptives used by the Baduy remote indigenous communities (Baduy KAT) in Lebak regency, Banten, West Java, Indonesia. According to data, the number of family planning acceptors among the Baduy community stood at 1,529 in February 2021 comprising 1,503 in Outer Baduy and  26  in Inner Baduy. In the beginning, most Baduy KAT used implants before they changed contraceptives  of their  choice. This study aims to reveal what channels are used to disseminate information about family planning, as well as to ensure the effectiveness of the innovations about family planning information they receive. The method used is explanatory survey, with a frequency distribution to analyze and determine the relationship between variables and  Spearman correlation analysis. The results showed that most respondents or 49% received family planning information from their relatives, 22% received it  from health workers (posyandu cadres), 21% received it  from village officials, 7% received it from  indigenous community leaders (kakolot), and only 1%  received it  from the media. This study found that there is a fairly strong relationship between communication channels and the effectiveness of innovation acceptance. Most of the respondents stated that they decided to accept the family planning innovations concept within 6 months by using humans as a communication channel, such as their relatives, health workers, village officials, and kakolot leaders.
Evaluar la resiliencia climática desde su correlación con las redes verdes urbanas. Aplicación en Zona Coyol, Veracruz, México
Authors: Avid Nava Eunice María , Winfield Reyes Fernando Noel
Published: January 2023

El presente documento refleja el modelo aplicado para evaluar la resiliencia climática en la Zona de estudio Coyol, en la ciudad de Veracruz, México, que forma parte de la tesis doctoral Redes verdes urbanas como conectoma para la resiliencia climática. La propuesta de un modelo de evaluación sistémica, ha considerado una estructura metodológica mixta a partir de tres dimensiones temáticas: existencia de nodos y enlaces verdes, enriquecimiento de las conexiones verdes urbanas y fortalecimiento del sistema urbano resiliente. Al exponer únicamente la dimensión vinculada al eje temático resiliencia climática, se expresan categorías clave como los servicios ambientales de la calidad del agua, aire, biodiversidad, de esta última destacando el control ambiental a través de la proporción de áreas verdes y su regulación climática, así como el efecto de isla de calor urbana. Además de ubicar y ponderar las estrategias urbanas de diseño ambiental, operación y mantenimiento, regulación y planificación urbano ambiental.
Serum lactate in asphyxic and non-asphyxic newborns: a historical cohort
Authors: Magalhaes Danilo , Peixoto Fernanda , Costa Paulo , Marques Solomar
Published: January 2023

INTRODUCTION: Perinatal asphyxia (AP) is the leading cause of death in the neonatal period and there is no consensus in the literature on its adequate diagnosis. Serum lactate is a promising laboratory marker and has been scarcely studied in the literature. OBJECTIVE: To associate serum lactate level with the diagnosis of perinatal asphyxia. Methods: This is a descriptive study of a historical cohort performed through the analysis of medical records of newborns with gestational age greater than or equal to 34 weeks, who had lactate levels in the first 24 hours of life and were admitted to the neonatal intensive care unit of the Clinics Hospital of the Federal University of Goiás, from 2015 to 2018. We analyzed the serum lactate level with one hour of life and 24 hours of life. Statistical analysis was performed using SPSS v.20 software (SPSS Inc.; Chicago, IL). RESULTS: The final sample consisted of 92 children, with a mean gestational age of 36.5 weeks, weight average of 2,746.7 grams, 52.2% male and 47.8% female. In children diagnosed with perinatal asphyxia, the serum lactate value in the first hour of life was significantly higher (p=0.003) compared to the non-asphyxiated group. At 24 hours of life there was a relative decrease in lactate value, but still remained higher in newborns with perinatal asphyxia. CONCLUSION: There was a strong association between increased serum lactate in the first hours of life and the diagnosis of perinatal asphyxia.
The effects of an intervention, in the light of the Bobath concept, on motor function, in children with cerebral palsy
Authors: Lobato Mafalda
Published: January 2023

The aim of this study was to assess the effects of an intervention in the light of the Bobath concept on motor function, in children with cerebral palsy. This is a systematic literature review that includes nine studies published between 2014 and 2019, and those were researched in three distinct databases: B-On; PubMed; ScienceDirect. The nine studies contemplated are indicative of the positive effects of the Bobath concept on the motor function of children with cerebral palsy, as well as on visual attention, contributing to the improvement and increase in the quality of life and independence in the daily living activities of these children. We concluded that the Bobath concept should integrate the physical therapy intervention which aims to improve the motor function of children with cerebral palsy. However, it is necessary to mention the need to carry out more studies that focus not only on the concept of Bobath, but also on the effects produced in motor function in this specific population.
Autoimmune hemolytic anemia in a patient with Kabuki syndrome - a case report in São Paulo and a brief discussion about Kabuki syndrome and association with autoimmunity
Authors: Lopes Aline , Hirose Maki , Silva Júnior Dário
Published: January 2023

Kabuki syndrome (KS), first described in Japan in 1981, is a rare disease characterized by a peculiar facies, postnatal growth deficiency, intellectual disability and a set of malformations, such as skeletal and visceral abnormalities. In the natural history of KS, abnormal immune events are presents and this case report contribute with the understanding and consolidation of hematologic autoimmune disorders. This article describes a case report of a patient with previous diagnosis of Kabuki syndrome with an autoimmune hemolytic anemia in a hospital of São Paulo, with adequate response and resolution with corticosteroids therapy. The article also makes a brief explanation of correlation with autoimmunity, immunodeficiency and Kabuki syndrome.
Pelger-Huët anomaly: a pediatric case report
Authors: Mundel Caroline , Cavalari Irides , Vieira Ana Paula , Follador Franciele , Wendt Guilherme , Ferreto Lirane
Published: January 2023

The Pelger-Huët anomaly (PHA) is a benign, hereditary, usually autosomal dominant condition characterized by bilobulated or completely non-segmented granulocytes and excessive chromatin aggregation that can be mistaken for band cells. PHA is a condition still poorly investigated in the medical literature, especially in developing nations. Errors in diagnosing PHA might cause wrong interpretation of leukograms. In this case, a pediatric patient (age 6) sought medical assistance due to a fever associated with diarrhea. After complete blood cell count (CBC), which showed an important left shift, PHA was suspected. The disease was confirmed with a new CBC and then followed by the family investigation for this anomaly. The younger brother and the mother were found to have the PHA. The father and the older brother were negative for the disease, thus indicating an autosomal dominant genetic transmission.
Designing educational material to teach Braille to adult educators through the method of distance learning
Authors: Skaraki Evaggelia
Published: January 2023

The primary purpose of this research is to design and implement educational material through the method of distance learning to teach Braille to adult educators. Another main aim of this study is to probe into the possibilities distance learning offers learners and to what extent it can be conducive to a proper and effective teaching of Braille to adult educators. More specifically, the educational material was examined by three experts in distance learning education who contributed to its evaluation and further development. Subsequently, the educational material was examined by five educators who evaluated it.
جريمة الزّنى ما بين الشريعة وأحكام العشائر ( دراسة فقهية معاصرة )
Authors: Ahmed Al-Tamimi Ahmed Sebti
Published: January 2023

الحمد لله رب العالمين والصلاة والسلام على سيدنا محمد وعلى آله وصحبه ومن سار على نهجه إلى يوم الدين.
أما بعد: 
فلا يخفى على أحد أنّ الفقه الجنائي الإسلامي قد بدأ بالنهوض برسالته من جديد في تهذيب المجتمع، التي كان قد تنحى عنها بسبب زيادة حقد الطاعنين لهذا الدين، فكان هدف الغرب أن استهدف كل مالهذا الدين من مبادئ وقيم، وحاول زرع الريبة والشك بين صفوف شبابنا، فاستحوذ على عقول نفر من الناس، كانوا خير عون لاعداء الإسلام في الطعن بالفقه الاسلامي جملة وتفصيلا.
فكان من جرّاء ذلك بعض الآراء الشاذة، والافكار المفتعلة، في تأويل الروايات والاخبار، وفي تفسير هذه الآية أو تلك، ومع كل ما يجري والقانون الوضعي وحكم العشيرة، يحكم العالم الإسلامي اجمعه، حتى تفشّت معه جريمة الزّنى، وانتشر الفساد، وساد الظلم، وكثُر معه الابتزاز خاصة في ظل انتشار الانترنت بين ابناء هذا الجيل، فأصبح المسلم يرنو ويتطلع إلى ماضيه حيث كانت تسود الشريعة وحكمها العادل مع الالتزام بالدين والقيم العربية الاصيلة، ونتيجة لذلك أصبحت تُعقد الحلقات الدراسية والمؤتمرات والندوات، لتساعد الناس في ازالة مما علق باذهانهم بأن الشريعة الاسلامية هي قانون ظالم، وهي ضد الانسانية وتشويه كل قيم الاسلام، فكانت الشريعة الاسلامية متكاملة الجوانب  أهدافها خيرة، مقاصدها نبيلة، وتبقى هي المتقدمة على ماسواها من قوانين واحكام من صنع البشر، فكان بحثنا الموسوم ( جريمة الزنى مابين حكم الشريعة والعشائر-دراسة فقهية معاصرة) قد القى الضوء على اخطر الجرائم في المجتمع الا وهي جريمة الزنى، يهدف البحث الى بيان خطورة جريمة الزنى وأثرها السلبي على الفرد والمجتمع بشكل عام، وقد أنكرتها كل الشرائع السماوية، بما فيها خاتمة الشرائع – شريعتنا الاسلامية- فضلا عن نبذها وبقوة من قبل العشائر، إذ لا يرتضيها أي مسلم لشرفه، وهذا مقصد من مقاصد الشريعة وهو الحفاظ على النسل.
الاستقلالية وعلاقتها بالسلوك الإيثاري لدى طلبة المرحلة الإعدادية
Authors: Jassim Shahbaa.A.
Published: January 2023

يهدف البحث الحالي التعرف على مستوى الاستقلالية والسوك الإيثاري ومعرفة العلاقة بينهما لدى طلبة المرحلة الإعدادية في مدينة تكريت إذ بلغت عينة  البحث  (100 ) طالب وطالبة من طالبات المرحلة الاعدادية، قامت الباحثة بالاعتماد على مقياس الاستقلالية الذي  أعده كل من حسن والتميمي (2010), والذي تكون بصورته النهائية من (36) فقرة موزعة على ستة مجالات ولكل مجال، ستة فقرات ، كما تبنت الباحثة مقياس السلوك الإيثاري المعد من قبل (الداوودي 2004)لطلاب المرحلة الإعدادية ،،حيث تكون المقياس من(28) موقفا ، حيث تم عرض المقياسين على مجموعة من المحكمين لاستخراج الصدق الظاهري لهما ، وكذلك استخراج معامل الثبات من خلال طريقة إعادة الاختبار وقد بلغ معامل ثبات مقياس الاستقلالية (0,84) ، أما معامل ثبات مقياس السلوك الإيثاري فقد بلغ (0,82) ويعدان معاملات ثبات جيدة ومقبولة. وقد اظهرت النتائج ما يأتي :
 

إن طلبة المرحلة الإعدادية لديهم مستوى عال من الاستقلالية في قضاء تكريت.
إن طلبة المرحلة الإعدادية لديهم مستوى عال من السلوك الإيثاري في قضاء تكريت.
هنالك علاقة ارتباطية موجبة بين الاستقلالية والسلوك الإيثاري.
Neuromorphic Sensor Event-Rate Monitoring for Satellite Characterization
Authors: Jolley Andrew , Afshar Saeed , Cohen Greg , Lazarus Pahlavani Richard , Lambert Andrew
Published: January 2023

A neuromorphic event-based camera was fitted to Electro Optic Systems’s 1.8 m telescope at Mount Stromlo in Canberra and used to observe 14 satellites in a variety of orbit regimes. Unique patterns in the fluctuations of each satellite’s event rate were analyzed to assess the utility of event-based sensors for satellite characterization. Event-rate curves were shown to be useful for determining the rotation rate of nonstabilized satellites, constraining the range of possible satellite orientations, and for differentiating between materials responsible for bright specular reflections in some cases.
COVID-19 and Family Schedule
Authors: Kovács Gusztáv
Published: January 2023

The delicate balance between the private and the public sphere affects families in a unique way, whose social place is to be found at the border of the two. Families are fundamental resources for the public – primarily due to their capacity to reproduce – however, they also rely strongly on the frameworks provided by the public. The latter affects especially the time schedule of families. Two current events have also challenged the sensitive balance between the two speres. The COVID-19 pandemic pushed certain public roles and activities over to the private sphere due to social distancing rules and compulsory lockdowns. Meanwhile, the energy crisis caused by the war delegates these public roles and activities to the private sphere.
Carotid artery stenting for stenosis after carotid artery replacement: An illustrative case report
Authors: Nagatsuka Hiroki , Miki Yuma , Tetsuo Yoshiaki , Yabuzaki Hajime , Nakayama Sadayoshi , Tanaka Yuko , Matsuda Yoshikazu , Tsumoto Tomoyuki , Terada Tomoaki , Mizutani Tohru
Published: January 2023

Background:

There are few reports on the treatment of carotid artery stenosis after arterial vessel replacement. We report and discuss an illustrative case of carotid artery stenting (CAS) performed for stenosis after carotid artery replacement.

Case Description:

A woman in her 20s experienced injury to the right carotid artery during an operation for removal of a carotid body tumor 6 years before presentation. The right common carotid artery and internal carotid artery were replaced with an artificial vessel graft at that time. Intraluminal stenosis in the graft was not identified 3 years after surgery; however, 4 years after surgery, stenosis was recognized at the non-anastomotic site inside the artificial vessel graft. Subsequently, antiplatelet therapy was initiated. The stenosis was noted to progress gradually in follow-up appointments. Therefore, we decided to intervene because of the patient’s young age and the risk of long-term hemodynamic stress. Angiography revealed pseudo-occlusion in the artificial vessel. Percutaneous transluminal angioplasty was performed for stenosis with distal protection; subsequently, CAS was performed. The patient was discharged without neurological deficits 4 days after the operation, and no apparent restenosis was observed as of the 1-year follow-up.

Conclusion:

Stenosis after cervical artery replacement can be safely treated with CAS. Inflation pressure and stent should be selected according to the pathology of the stenosis.
COMPARATIVE EVALUATION OF N-ACETYLCYSTEINE AND DEXAMETHASONE EFFECTS ON THE CLINICAL COURSE OF UVEITIS IN AN EXPERIMENT
Authors:   Grodno State Medical University, Grodno, Belarus, Marmysh V. G.
Published: January 2023

Objective. To evaluate and compare the effects of the parenteral administration of N-acetylcysteine (NAC), dexamethasone and their combination on the clinical course of experimental immunogenic uveitis (EIU). Material and methods. The experimental study was carried out on 72 rabbits (144 eyes), eight of which were intact. The animals with EIU were divided into 8 groups (8 in each), which received parenteral injections of placebo, NAC, dexamethasone or a combination of NAC and dexamethasone and were withdrawn from the experiment on the 3rd or 7th day. A clinical assessment of the uveitis course by external examination and biomicroscopy was performed on the 3rd and 7th day. The severity of clinical signs of uveitis was estimated in score points according to 7 criteria. Results. NAC parenteral administration led to a significant improvement in the clinical picture of EIU. Dexamethasone had a stronger anti-inflammatory effect comparing to NAC. The combination of NAC and dexamethasone showed pharmacological synergy of action, which made it possible to increase the effectiveness of therapy. Conclusion. 1. Parenteral administration of NAC significantly reduces the intensity of the local inflammatory reaction in EIU. 2. NAC and dexamethasone have a mutually potentiating pharmacological effect, which can significantly increase the effectiveness of anti-inflammatory therapy of EIU. 3. The results of the study serve as an objective justification for the inclusion of NAC in the complex therapy of uveitis, in particular in combination with dexamethasone.
MODELS AND METHODS OF MAKING MANAGERIAL DECISIONS IN MANAGEMENT
Authors:   Lviv State University of Physical Culture named after Ivan Boberskyj, Pavlenchyk Nataliia , Pawlowski Grzegorz ,   Zaklad Handlowo-Uslugowy BHP,, Mysiuk Iryna ,   Ivan Franko National University of Lviv, Tyrkalo Yuriy ,   Lviv Polytechnic National University, Kurilina Oksana ,   National Defence University of Ukraine named after Ivan Cherniakhovskyi
Published: January 2023

The activity and development of any enterprise is directly related to the conditions, as well as to the development, adoption and implementation of management decisions (or business decisions) aimed at solving a certain management problem. It was determined that the research of conditions and methods of making rational decisions in management, including the optimization of business decisions, is a relevant issue today. With this in mind, in the article presents the models and methods of making managerial decisions in management based on the research results. It is noted that the management decision under conditions of risk and/or uncertainty should be understood as the choice of the most effective business solution option from possible alternatives under conditions of risk and/or uncertainty, and the main goal of the management decision is to achievement of enterprise goals. At the same time, it was found that in conditions of complete uncertainty, the criteria for making business decisions are important, in particular, the criterion related to the result and the costs of resources and time incurred to obtain this result. It was concluded that rational managerial decisions in management are determined in the process of optimization. It is advisable to carry out further research in the direction of determining the optimal allocation of resources in conditions of uncertainty and risk, taking into account the models and methods of making business decisions in management for the purpose of enterprise development, taking into account the result, process, stability, quality and effective management.
BORROWING THE EXPERIENCE OF INTERNATIONAL REGULATORY AND LEGAL REGULATION OF PUBLIC CONTROL RELATIONS OVER THE ACTIVITIES OF PUBLIC ADMINISTRATION SUBJECTS
Authors:   State University of Trade and Economics, Mushenok Viktor
Published: January 2023

The article examines the state of normative and legal consolidation of certain rights of public representatives of our country to participate in the management of state affairs, in particular, the right of public control over the activities of public administration. That is, the legislative possibilities of individual private individuals and/or public associations regarding the inspection or monitoring of the activities of public administration subjects, which ensure the public interest, have been analyzed. In the context of ensuring the achievement of the research goal, the author considered in the article international normative legal acts, which contain the main principles of regulating relations to ensure public interest and the authority of the public to interact with state authorities. In particular, the author drew attention to the Universal Declaration of Human Rights, the Convention for the Protection of Human Rights and Fundamental Freedoms, the International Covenant on Civil and Political Rights, the European Social Charter, the Convention on Access to Information, public participation in the decision-making process and access to justice on issues , relating to the environment (Aarhus Convention), Recommendations of the Committee of Ministers of the Council of Europe on the participation of citizens in local public life, etc. The analysis of the researched international normative legal acts formed the grounds for ascertaining the fact of extreme importance for the development of relations of control public activity in Ukraine of the normative and legal consolidation of conditions for the activity of public associations according to international models. It is proposed to support the adoption (with author's additions) by the Verkhovna Rada of Ukraine of the Draft Law of Ukraine "On Public Control" as a special legislative act in the sphere of regulation of legal relations of public control over the activities of public administration. It is proposed to supplement the Draft Law of Ukraine "On Public Control" with international legal norms regarding: guaranteeing citizens the right of access to clear, comprehensive information about various matters concerning their local communities; the right to speak about the most important decisions affecting their future; promoting a culture of democratic participation in public affairs; to encourage citizens to take responsibility for their own public activities.
THE GENERAL CHARACTERISTICS OF EXTERNAL MANIFESTATION OF PROCEDURAL COMPONENT VERIFICATION OF DECISIONS BY DISCUSSION AS FUNDAMENTAL PRINCIPLE OF DECISION-MAKING BY THE PARLIAMENT OF UKRAINE
Authors:   Yaroslav Mudryi National Law University, Liubchenko Oleksii
Published: January 2023

The article provides the general characteristics of external manifestation of procedural component verification of decisions by discussion as fundamental principle of decision-making by the parliament of Ukraine, which is considered in the light of the interaction of the Verkhovna Rada of Ukraine with other subjects. The openness and transparency of the parliament of Ukraine functioning are analyzed through the prism of scientific works, current legislation and legal positions of the Constitutional Court of Ukraine. Special attention is paid to parliamentary hearings, their preparation and holding, because during the appropriate form of work of the parliament, the public participates in the discussion of decisions approved by the Verkhovna Rada of Ukraine, and stakeholders can express their position publicly. It is noted that despite the advisory nature of the results of the parliamentary hearings, the specified institute is evaluated as a feedback mechanism between citizens, institutions of civil society and the Verkhovna Rada of Ukraine, which makes it possible to analyze the position of society on certain issues and take it into account when working with draft laws in the committees of the Verkhovna Rada. Attention is paid to the fact that in addition to parliamentary hearings as a classic form of interaction between the representative body of the state power of Ukraine and institutions of civil society, the corresponding interaction can also take place in other forms, in particular, through electronic democracy (for example, electronic petitions, discussions of draft laws) or within the scope of the work of people's deputies in constituencies (for example, during meetings with voters). It is noted that electronic petitions and discussion of draft laws as digital services of the parliament website also represent the external manifestation of the procedural component of the fundamental principle of decision verification by discussion, because with their help it is possible to involve an unlimited circle of citizens and institutions of civil society in the process of development and decision-making by the Verkhovna Rada of Ukraine. Thus, domestic legislation providesfor a significant number of mechanisms for the interaction of the Parliament of Ukraine with other subjects. At the same time, it should be noted the tendency to strengthen the role of the mechanisms of "electronic democracy" (e-democracy) in the formation of public debate regarding the relevant draft acts and adopted decisions. The introduction of such mechanisms contributes to the strengthening of control by civil society and the formation of a professional discussion with the broad involvement of specialists and stakeholders in the context of decision-making by the legislature.
ABOUT SOME ISSUES OF THE EXECUTION OF CIVIL PROCEEDINGS IN THE CONDITIONS OF MARTIAL LAW
Authors:   Yaroslav Mudryi National Law University, Cherevatenko Iryna , Herhulenko Tetiana ,   Yaroslav Mudryi National Law University
Published: January 2023

This article is aimed at an analysis of the implementation of civil justice in the conditions of martial law, taking into account features that may arise in view of the temporary occupation, the conduct of active combat action, and the restoring of court activities as a result of de-occupation. For full awareness and understanding of the subject of our research, considerable attention was paid to some legislative acts, which make it possible to understand the essence of the changes that were made as a result of a full-scale war and the need to adapt legislation to wartime conditions. In addition, during the study, this problem was analyzed in the context of Article 6 of the European Convention on Human Rights and it was emphasized that all emergency changes that may be made should not violate the right to a trial provided by this convention. The article analyzes the correlation between the concepts of procedural law analogy and "adjustment" of current procedural norms to new realities. Considering the fact that there is no analogy in the process at the legislative level, the recommendations given by the Council of Judges of Ukraine regarding the adaptation of the current procedural norms can be perceived as an analogy, in view of this, the question of the correlation of these legal aspects was analyzed. During the research, considerable attention was paid to the change of territorial jurisdiction due to the conduct of combat action and the impossibility of functioning of the courts. The procedure, order and features of such changes are analyzed. The article examined the principles of civil justice and the importance of their observance during the implementation of civil justice in the conditions of martial law. The principles of "procedural economy" and the reasonableness of terms significantly contribute to increasing the efficiency and effectiveness of court activities.
Das Kompetenzatelier als agiles Lehrformat
Authors: Kruppke Benjamin , Apelt Sabine , Hartwig Carl Eric , Koch Adrian , Mai Julian , Schumann Anna Lorena , Ulbricht Tim Johannes , Ullmann Moritz , Wiesmann Hans-Peter
Published: January 2023

Um den Campus im Zeitalter von digitalen und hybriden Lehrveranstaltungen wieder attraktiv zu machen, wird ein agiles Lehrformat vorgestellt, das die kooperative Problembewältigung durch projektbasiertes Lernen und agiles Projektmanagement ins Zentrum stellt. Hierzu werden zunächst allgemein die Elemente agilen Projektmanagements vorgestellt und anschließend die Übertragung auf den Lehrkontext erläutert. Zur weiteren Verdeutlichung des Ablaufs und des Zusammenspiels der Gruppenmitglieder wird am konkreten Beispiel des Moduls Kompetenzatelier: Biomechanik agil mit Scrum die Durchführung beschrieben und das schrittweise Erstellen eines Demonstrators durch die Studierenden gezeigt. Abschließend wird die Evaluation des Kompetenzateliers zur Identifizierung von allgemeinen Stärken und Schwächen genutzt. Dabei wird besonders auf die agile Reaktion der Studierenden auf geplante und ungeplante „Störelemente“ eingegangen. Das Kompetenzatelier bietet für Lehrende kleiner Studiengänge und Gruppen eine Anregung zur innovativen und kreativen Auseinandersetzung mit einem agilen Projektmanagement und fördert die Selbstmotivation zum Lernen durch eine unmittelbare praktische Anwendung.
Evaluation zur Wirksamkeit der Lehre im Modul Mess- und Automatisierungstechnik
Authors: Schlegel Beatrice , Wermann Caroline , Odenbach Stefan
Published: January 2023

Ausgelöst durch die Corona-Bedingungen wurde in den letzten Jahren viel in der Lehre verändert. Dabei stellt sich die Frage, welche Elemente der Lehre – digitale wie nicht digitale – für den Lernprozess der Studierenden tatsächlich förderlich sind. Um sich dieser Fragestellung anzunähern, wurde für das Modul Mess- und Automatisierungstechnik ein Evaluationskonzept entwickelt und im Sommersemester 2022 erstmals umgesetzt, mit dem Ziel,  die studentische Perspektive auf diese Frage zu erfassen. Im folgenden Artikel werden das Konzept und Ergebnisse vorgestellt und kritisch diskutiert. Außerdem wird der Nutzen einer Evaluation konkreter Lehr-Lernelemente für die Weiterentwicklung der Lehre hervorgehoben. Dieser wird gesteigert, je häufiger eine Evaluation durchgeführt wird – in nachfolgenden Semestern, in anderen Modulen oder auch an anderen Universitäten. Ein klares Ergebnis dieser Evaluation ist die Bevorzugung von Präsenzveranstaltungen (auch in Ergänzung der Möglichkeit, online teilzunehmen) gegenüber reinen Online-Angeboten.
Entwicklung und Auswertung der Evaluation von Praktika@home
Authors: Wermann Caroline , Schlegel Beatrice , Odenbach Stefan
Published: January 2023

Aufgrund der Corona-Pandemie wurden viele Lehrveranstaltungen auf neue Formate umgestellt, häufig kurzfristig und ohne die Möglichkeit einer strukturierten Erprobung. Im Modul Mess- und Automatisierungstechnik wurden die Praktika@home entwickelt, die nach dem Blended-Learning-Konzept durchgeführt werden. Um zu evaluieren, wie gut das Lehrangebot die Studierenden bei der Erreichung der Lernziele unterstützt, wurde ein Fragebogen erarbeitet. Die Gestaltung und Auswertung der Ergebnisse werden anhand des erstmals im Sommersemester 2022 durchgeführten Experiments ‚Dehnungsmessung‘ beschrieben und kritisch diskutiert.
Die Ergebnisse der Evaluation zeigen, dass das Betreuungskonzept während der Praktika überarbeitet werden muss. Aus den Freitext-Kommentaren, die von den Studierenden ausgiebig genutzt wurden, konnten Ansatzpunkte für diese Veränderung identifiziert werden. Darüber hinaus kann abgeleitet werden, dass eine bessere Abstimmung zwischen Vorlesung und Praktikum notwendig ist. Zuletzt wurden Vorschläge zur Verbesserung des Fragebogens erarbeitet.
Hereditary diseases and carrier’s screening programs in genetically isolated populations
Authors: М.Т. Саввина, , Н.Р. Максимова, , А.Л. Сухомясова, , И.Н. Лебедев,
Published: January 2023

Генетические изоляты - особый тип популяций, которые на протяжении многих веков держались обособленно, демонстрируя меньшую генетическую изменчивость и отличаясь по своей генетической структуре от представителей других групп. Высокая степень изоляции малочисленных популяций человека на протяжении многих поколений создавала условия для дрейфа генов. Вследствие популяционных механизмов, таких как эффект основателя или эффект бутылочного горлышка, в изолированных популяциях наблюдается отягощение генетическим грузом наследственных заболеваний, что негативно воздействует на социально-экономический уровень, а также качество жизни населения. В настоящем обзоре изложены сведения о наследственных болезнях, обнаруженных в изолированных популяциях мира, о существующих программах молекулярно-генетического скрининга гетерозиготного носительства мутаций в генах наследственных болезней и о целесообразности внедрения таких программ в практику медико-генетического консультирования.

There are populations that have kept apart for many centuries, show less genetic variability and they differ in their genetic structure from representatives of other groups - genetic isolates. The high degree of isolation of small human populations for many generations has created good conditions for gene drift. Due to population mechanisms, such as the founder effect or the bottleneck effect there is a genetic burden of hereditary diseases, which observed in isolated populations, that negatively affects both social and economic level, as well as the quality of life. This review provides information about hereditary diseases in genetically isolated populations, existing carrier’s screening programs and the feasibility of its implementation.
Leigh syndrome: clinical and molecular genetic features, modern approaches to diagnosis and therapy
Authors: Д.В. Кистол, , П.Г. Цыганкова, , Е.Ю. Захарова,
Published: January 2023

Митохондриальные заболевания - клинически и генетически гетерогенная группа заболеваний, возникающих в результате нарушения окислительного фосфорилирования в митохондриях. Одним из наиболее распространенных представителей этой группы среди пациентов детского возраста является синдром Ли или подострая некротизирующая энцефаломиелопатия - тяжелое нейродегенеративное заболевание, манифестирующее в раннем детском возрасте. Характерными нейрорадиологическими признаками являются двусторонняя симметричная гипоинтенсивность в базальных ганглиях на компьютерной томограмме или двусторонние симметричные гиперинтенсивные очаги в стволе головного мозга и/или базальных ганглиях на Т2-взвешенной магнитно-резонансной томограмме. В настоящее время известно более 80 генов, ответственных за развитие заболевания, что значительно затрудняет диагностику. В данном обзоре рассмотрены основные клинические и молекулярно-генетические особенности синдрома Ли, а также современные подходы возможной медикаментозной и этиотропной терапии. Представлен алгоритм комплексной диагностики синдрома Ли с учетом данных об особенностях спектра и частот мутаций у пациентов из России.

Mitochondrial diseases are clinically and genetically heterogeneous group of inherited diseases resulting from impaired oxidative phosphorylation in mitochondria. One of the most common representatives of this group among children is Leigh syndrome, or subacute necrotizing encephalomyelopathy, a severe neurodegenerative disease with manifestation in childhood. The characteristic neuroradiological features are bilateral symmetrical hypointensities in the basal ganglia on CT or bilateral symmetrical hyperintense lesions in the brainstem and/or basal ganglia on T2-weighted MRI. Currently, 80 genes are known that are responsible for the development of LS, which significantly complicates the diagnosis. In the review we provide clinical and molecular genetic features, current approaches in diagnostic and treatment for LS. Finally, an algorithm for the complex diagnosis of LS including regional aspects of mutational spectrum is described.
Evaluation of the role of thrombophilia gene polymorphism in infertility in women from the Republic of Bashkortostan
Authors: А.Т. Сугурова, , Р.И. Хусаинова, , А.Г. Ящук,
Published: January 2023

Проведен поиск ассоциаций полиморфных локусов генов тромбофилии с бесплодием и различным ответом яичников на стимуляцию овуляции. На основании данных акушерского анамнеза 280 женщин были разделены на три группы в зависимости от наличия репродуктивного нарушения: 1 группа - женщины с бесплодием (n=83); 2 группа - женщины с привычным невынашиванием беременности (n=79). В группу сравнения входили женщины с несколькими срочными родами, без наследственной тенденции к образованию тромбов (n=118). Исследование проводилось методом полимеразной цепной реакции в реальном времени. Статистический анализ выполнен с применением критерия Краскелла-Уоллеса, медианного теста, критерия χ2 Пирсона, использовали пакет программ Statistica 12. Выявлена ассоциация аллеля G локуса rs1799963 гена F2, аллеля G и генотипа GG локуса rs6025 гена F5 с бесплодием. Обнаружены ассоциации аллеля G и генотипа GG локуса rs6046 гена F7 с бедным ответом на стимуляцию овуляции, а также с гиперответом яичников.

A search was made for associations of polymorphic thrombophilia gene loci with infertility and different ovarian responses to ovulation stimulation. Based on obstetric anamnesis data, 280 women were differentiated into three groups depending on the presence of a reproductive disorder: group 1 - women with infertility (n=83); Group 2 - women with habitual miscarriage (т=79). The comparison group included women with multiple term deliveries without a hereditary tendency to form blood clots (n=118). The study was conducted using real-time polymerase chain reaction. Statistical analysis was performed using the Kruskell-Wallace criteria, median test, Pearson’s χ2 test, using the Statistica 12 software package. The association of the G allele of the rs1799963 locus of the F2 gene, the G allele and the GG genotype of the rs6025 locus of the F5 gene with infertility was revealed. Associations of the G allele and the *GG genotype of the rs6046 locus of the F7 gene with a poor response to ovulation stimulation, as well as with ovarian hyperresponse, were found.