bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the development of professional values in an online RN-to-BSN program
Authors: Knecht Linda D’Appolonia , Dabney Beverly W , Cook Lauren E , Gilbert Gregory E
Published: July 2019

Background:

Development of professional nursing values is critical within registered nurse–to–bachelor of science in nursing programs to prepare nurses for increasingly complex and diverse work environments. The results of previous studies have been inconsistent, with few studies focusing on online registered nurse–to–bachelor of science in nursing programs. In addition, little is known regarding the effectiveness of the educational methods used to support advancement of professional values and ethical practice.

Objective:

The object of this study was to gain an understanding of nursing students’ attitudes and beliefs about professional values at entry and exit of an online registered nurse–to–bachelor of science in nursing program that includes a standalone ethics course and integrates American Nurses Association Code of Ethics provisions throughout the curriculum.

Research design:

For this one-group pretest–posttest, quasi-experimental design, longitudinal matched-pair data were gathered at program entry and exit using the Nurses Professional Values Scale–Revised.

Participants and research context:

In all, 119 students of an online registered nurse–to–bachelor of science in nursing program at a Midwest public university who completed entry and exit surveys between spring 2015 and spring 2018 were included in this study.

Ethical considerations:

This study was reviewed and determined to be exempt by the university’s institutional review board.

Findings:

The results showed a significant increase in total posttest scores when considering all participants. However, students who took the ethics course after the pretest demonstrated a significant increase in posttest scores, while students who took the ethics course prior to the pretest demonstrated a small increase that was not statistically significant. Significant increases were also found in the professionalism, activism, and trust factors.

Discussion:

This study supports previous study findings where students scored higher on caring and lower on activism and professionalism factors. The largest gains were made after completing the ethics course.

Conclusion:

The results suggest that requiring a standalone ethics course in the registered nurse–to–bachelor of science in nursing curriculum had a positive impact on self-reported professional values.
The decline of Western European social democracy: Exploring the transformed link between welfare state generosity and the electoral strength of social democratic parties, 1975–2014
Authors: Loxbo Karl , Hinnfors Jonas , Hagevi Magnus , Blombäck Sofie , Demker Marie
Published: July 2019

Social democratic parties are crumbling at the polls. Surprisingly, however, the causes of this demise remain largely unexplored. This article contributes to filling this gap in the research by studying the long-term impact of welfare state generosity on the vote share of social democratic parties in 16 Western European democracies. If the welfare state indeed was a key factor behind social democratic growth in the past, we ask whether the recent plight of these parties is down to a reversal of their previously dominant success factor? The article makes three principal findings. First, we show that social democratic parties primarily benefited electorally from expansive reforms at lower levels of welfare state generosity. Second, we find that this dynamic of diminishing returns also helps explain the demise of the social democratic party family in the whole of Western Europe. Lastly, our results reveal that programmatic turns to the right predict electoral losses in the least generous welfare states, whereas such shifts either pass unnoticed or predict vote gains in the most generous ones. We conclude by arguing that the structure of welfare state institutions is one important explanation for variations in the demise of the once powerful social democratic party family.
Noise as Dysappearance: Attuning to a Life with Type 1 Diabetes
Authors: Kingod Natasja , Cleal Bryan
Published: July 2019

In this article, we use noise as a metaphor for the overload of information – embodied, technological and online social – that characterizes life with type 1 diabetes. Noise illustrates embodied sensations of fluctuating blood glucose, measurement problems and alarms from digital self-care devices and irrelevant or emotionally disturbing posts on Facebook. Attunement is crucial to the quality of self-care achieved by individuals and comprises: (1) developing skills to receive clear signals from the body, (2) adjusting and individualizing self-care technologies to bodies and daily lives and (3) discerning appropriate distracting and unhelpful self-care information. Ideally, life with type 1 diabetes is harmonious, with clear messages from bodies, technologies and Facebook that enable better self-care.
Neuroprotective Effects of Exercise on the Morphology of Somatic Motoneurons Following the Death of Neighboring Motoneurons
Authors: Chew Cory , Sengelaub Dale R.
Published: July 2019

Background. Motoneuron loss is a severe medical problem that can result in loss of motor control and eventually death. We have previously demonstrated that partial motoneuron loss can result in dendritic atrophy and functional deficits in nearby surviving motoneurons, and that treatment with androgens can be neuroprotective against this dendritic atrophy. Exercise has also been shown to be protective following a variety of neural injury models and, in some cases, is dependent on androgen action. Objective. In this study, we explored whether exercise shows the same neuroprotective effect on induced dendritic atrophy as that seen with androgen treatment. Methods. Motoneurons innervating the vastus medialis muscles of adult male rats were selectively killed by intramuscular injection of cholera toxin-conjugated saporin. Following saporin injections, some animals were allowed free access to a running wheel attached to their home cages. Four weeks later, motoneurons innervating the ipsilateral vastus lateralis muscle were labeled with cholera toxin-conjugated horseradish peroxidase, and dendritic arbors were reconstructed in 3 dimensions. Results. Dendritic arbor lengths of animals allowed to exercise were significantly longer than those not allowed to exercise. Conclusions. These findings indicate that exercise following neural injury exerts a protective effect on motoneuron dendrites comparable to that seen with exogenous androgen treatment.
Radiographic Healing and Functional Outcomes of Untreated Ulnar Styloid Fractures Following Volar Plate Fixation of Distal Radius Fractures: A Prospective Analysis
Authors: Okoli Michael , Silverman Matthew , Abboudi Jack , Jones Christopher , Kirkpatrick William , Liss Frederic , Takei T. Robert , Wang Mark , Ilyas Asif M.
Published: July 2019

Background: Ulnar styloid fractures (USFs) are common concomitant injuries associated with distal radius fractures (DRFs). Recent studies have found conflicting evidence on whether these fractures treated or untreated effect pain and functional outcomes. The purpose of this study was to prospectively evaluate pain and function outcomes of consecutively untreated USFs in surgically repaired DRFs. The study hypothesis was that there would be no difference in outcomes whether an USF is present or not, with all cases left untreated. Methods: A prospective study at a single institution of consecutive DRF treated surgically with volar locked plating was undertaken. No patients underwent fixation of an USF if present. There were no treated USF that were excluded. Patients with associated ulnar neck and shaft fractures were excluded. Functional outcome measures were analyzed using the Quick Disabilities of the Arm, Shoulder, and Hand score (QDASH) and the Patient-Rated Wrist Evaluation (PRWE) scores. Outcome measures were collected at 3 months and 1 year postoperatively. Results: There was an incidence of 52.2% (n = 70/134) USF associated with surgically treated DRF. By location, there were 52.9% (n = 37/70) ulnar styloid tip fractures and 46.1% (33/70) ulnar styloid base. There were 75.7% of USF (53/70) still not healed by 1-year follow-up. When comparing patients with a DRF without an USF versus DRF with an associated USF at 12 months, there was no statistical difference in the QDASH score (6.7 vs 8.4, P = .47) or the PRWE total score (4.8 vs 7.5, P = .24). Similarly, subgroup analysis showed no statistical difference in QDASH or PRWE scores at final follow-up in united USF versus nonunited USF subjects (QDASH 14.2 vs 6.8, P = .112; PRWE 14.8 vs 5.4, P = .185). Conclusions: USFs are a common concomitant injury occurring in nearly half of DRFs treated surgically. Our prospective cohort analysis showed that neither the presence, type, nor bony union status of a concomitant USF has any significant effect on patient outcomes or reoperations at 1-year postoperatively. Our study confirms our hypothesis that USF of the tip and base should be left untreated.
Synthesis of 1,2,3-triazole-substituted 6,7-dihydroindolizin-8(5H)-one derivatives mediated by Selectfluor
Authors: Huang Yulin , Lei Jiaying , Fu Xinliang , Xie Wenlin , Li Xiaofang
Published: July 2019

The 1,2,3-triazole and 1 H-1,2,3-benzotriazole-substituted 6,7-dihydroindolizin-8(5 H)-one derivatives were synthesized by the reaction of ( E)-7-(arylmethylidene)-6,7-dihydroindolizin-8(5 H)-ones with 1,2,3-triazole and 1 H-1,2,3-benzotriazole in the presence of Selectfluor in moderate yield. The structures of all the products were characterized thoroughly by nuclear magnetic resonance, infrared, and high-resolution mass spectrometry together with X-ray crystallographic analysis.
Design, synthesis, and nematicidal activities of novel 1,3-thiazin(thiazol)-4-one derivatives against Meloidogyne incognita
Authors: Jia Haowu , Guo Wei , Li Wei , Li Tingfang , Chen Xiulei , Li Zhong , Xu Xiaoyong
Published: July 2019

Four series of novel 1,3-thiazin(thiazol)-4-one derivatives were synthesized by Suzuki coupling. Preliminary bioassays showed that most of the synthesized compounds exhibited good inhibitory activity in vivo against root-knot nematodes, Meloidogyne spp. at 20 mg L−1. Among the tested compounds, we found that two compounds displayed 46.4% and 41.4% inhibitory activity even at 1 mg L−1, respectively.
“That’s the Point of Going”: A Qualitative Inquiry Into the Experiences of Black Males at an Early College High School
Authors: Adams Tempestt R. , Williams Brian K. , Lewis Chance W.
Published: July 2019

Early college high schools are small schools designed to increase college and career readiness for groups underrepresented in higher education. While some research has focused on student experiences in the early college environment, few have specifically examined the perceptions of Black male students. The purpose of this study was to examine the perceptions of Black males in an early college high school. Using a qualitative case study design, data were collected using focus groups and individual interviews. Emergent themes included students’ descriptions of their learning environment and the benefits and challenges they experienced. The results of this study provide further insight into early college high schools and how they serve their targeted population.
A structured classification of the types of pain research studies accessed by different health professionals involved in pain management
Authors: Arumugam Vanitha , MacDermid Joy C , Grewal Ruby , Uddin Zakir
Published: July 2019

Objectives:

The aim of this study was to describe the information access behaviours of clinicians involved in pain management with respect to their use of a pain evidence resource and to determine the areas of professional differences.

Methods:

Users (n = 258) of a free pain evidence alerting service (PAIN+) were enrolled in this study. The users regularly received email alerts about newly published clinical articles about pain that were pre-appraised for scientific merit and clinical relevance. A sample of up to 10 abstracts retrieved by each user were retrieved and classified using a descriptive classification system to describe the types of research, pain subtypes, interventions and outcomes that were reported in the accessed studies. Frequencies and chi-square tests were performed to compare access behaviours across professions.

Results:

A total of 258 participants viewed 2311 abstracts. More than 52% of abstracts viewed were primary clinical studies; the majority (87%) addressed treatment effectiveness and were quantitative research (99.8%). The most commonly accessed clinical topic (58%) related to musculoskeletal pain and the most accessed pain type was chronic pain (76%). Drugs, injections and rehabilitation therapy were most commonly addressed in accessed intervention studies. Differences in professional focus were reflected in access: physicians/nurses accessed studies on injections (23%) and drugs (26%) and nurses accessed surgical studies, whereas other professions rarely did. Physiotherapists (PTs) and occupational therapists (OTs) preferentially accessed studies on rehabilitation. OTs and psychologists preferentially accessed the available studies on cognitive interventions; OTs accessed more ergonomic studies. Psychologists most accessed educational and psychosocial intervention studies. There were no differences in access across professions to multidisciplinary interventions.

Conclusion:

While access partially reflects the content of the pain repository, professional differences in access were evident that related to the nature of the intervention, type of pain and the research design. Multidisciplinary evidence repositories may need to consider how to include and meet varied information needs.
Urolithiasis in children and exposure to melamine: A review of the epidemiological literature
Authors: Swaen Gerard MH
Published: July 2019

Melamine (ME) is a high production volume compound, mainly used for the synthesis of ME-formaldehyde resins. There is an extensive toxicological and epidemiological database on this compound, but the epidemiology has so far not been reviewed. An extensive literature search in PubMed was conducted and relevant ME epidemiology studies were identified and assessed. The epidemiology data nearly entirely consisted of studies on the health effects due to the food tampering catastrophe in China discovered in 2008 where ME was intentionally added to powdered milk products. Most of these studies were aimed at assessing the extent of the catastrophe and the clinical follow-up of affected children. A reliable dose–response relationship could not be derived from the epidemiology studies. However, they do contain several strong data points that can assist in ranging the No Observed Adverse Effect Level (NOAEL) for humans, for children in particular.
Cardiovascular safety of nintedanib in subgroups by cardiovascular risk at baseline in the TOMORROW and INPULSIS trials
Authors: Noth Imre , Wijsenbeek Marlies , Kolb Martin , Bonella Francesco , Moros Lizette , Wachtlin Daniel , Corte Tamera J.
Published: July 2019

Nintedanib is a tyrosine kinase inhibitor used to treat idiopathic pulmonary fibrosis (IPF). We investigated the cardiovascular safety of nintedanib using pooled data from the TOMORROW and INPULSIS trials.

Cardiovascular events were assessedpost hocin patients with a history of atherosclerotic cardiovascular disease (CVD) and/or one or more cardiovascular risk factors at baseline (“higher cardiovascular risk”) and patients with no history of atherosclerotic CVD and no cardiovascular risk factors at baseline (“lower cardiovascular risk”).

Incidence rates were calculated for 1231 patients (n=723 nintedanib and n=508 placebo), of whom 89.9% had higher cardiovascular risk. Incidence rates of major adverse cardiovascular events were similar in the nintedanib and placebo groups in patients with higher cardiovascular risk (3.88 (95% CI 2.58–5.84) and 3.49 (95% CI 2.10–5.79) per 100 patient-years, respectively) and lower cardiovascular risk (4.78 (95% CI 1.54–14.82) and 5.37 (95% CI 1.73–16.65) per 100 patient-years, respectively). Incidence rates of myocardial infarction in the nintedanib and placebo groups, respectively, were 3.03 (95% CI 1.91–4.81) and 1.16 (95% CI 0.48–2.79) per 100 patient-years in patients with higher cardiovascular risk and 1.59 (95% CI 0.22–11.29) and 1.78 (95% CI 0.25–12.64) per 100 patient-years in patients with lower cardiovascular risk. Incidence rates of other ischaemic heart disease in the nintedanib and placebo groups, respectively, were 1.85 (95% CI 1.02–3.34) and 3.28 (95% CI 1.94–5.54) per 100 patient-years in patients with higher cardiovascular risk and 0 and 1.80 (95% CI 0.25–12.78) per 100 patient-years in patients with lower cardiovascular risk.

These data help to establish the cardiovascular safety profile of nintedanib in IPF.
Ambient neutron and photon dose equivalent H*(10) around a pencil beam scanning proton therapy facility
Authors: Sharma Dayananda Shamurailatpam , Patro Kartikeswar CH , Manthala Padannayel Noufal , Arjunan Manikandan , Krishnan Ganapathy , Thiyagarajan Rajesh , Chilukuri Srinivas , Jalali Rakesh
Published: July 2019

Objectives:

To measure leakage ambient dose equivalent H*(10) from stray secondary neutron and photon radiation around proton therapy (PT) facility and evaluate adequacy of shielding design.

Methods and materials:

H*(10) measurement were carried out at 149 locations around cyclotron vault (CV), beam transport system (BTS) and first treatment room (GTR3) of a multiroom PT facility using WENDI-II and SmartIon survey meter. Measurement were performed under extreme case scenarios wherein maximum secondary neutrons and photons were produced around CV, BTS and GTR3 by stopping 230MeV proton of 300nA on beam degrader, end of BTS and isocenter of GTR3. Weekly time average dose rate (TADR) were calculated from H*(10) value measured at selective hot spots by irradiating actual treatment plans of mix clinical sites.

Results:

The maximum total H*(10) were within 2 µSv/hr around CV, 5 µSv/hr around outer wall of BTS which increases up to 62 µSv/hr at the end of inside BTS corridor. Maximum H*(10) of 20.8 µSv/hr in treatment control console (P125), 23.4 µSv/hr behind the common wall between GTR3 and GTR2 (P132) and 25.7 µSv/hr above isocenter (P99) were observed around GTR3. Reduction of beam current from 6 to 3 nA and 1 nA at nozzle exit lead to decrease in total H*(10) at P125 from 20.8 to 11.35 and 4.62 µSv/hr. In comparison to extreme case scenario, H*(10) value at P125, P132 and P99 from clinically relevant irradiation parameters were reduce by a factor ranging from 8.6 for high range cube to 46.4 for brain clinical plan. The maximum weekly TADR per fraction was highest for large volume, sacral chordoma patient at 8.5 µSv/hr compare to 0.3 µSv/hr for brain patient. The calculated weekly TADR for 30 mix clinical cases and 15 fractions of 1 L cube resulted total weekly TADR of 83–84 µSv/hr at P125, P132 and P99. The maximum annual dose level at these hot spots were estimated at 4.37 mSv/Yr.

Conclusion:

We have carried out an extensive measurement of H*(10) under different conditions. The shielding thickness of our PT facility is adequate to limit the dose to occupational worker and general public within the permissible stipulated limit. The data reported here can bridge the knowledge gap in ambient dose around PT facility and can also be used as a reference for any new and existing proton facility for intercomparison and validation.

Advances in knowledge:

First extensive investigation of neutron and photon H*(10) around PT facility and can bridge the knowledge gap on ambient dose.
One-year test-retest reliability of ten vision tests in Canadian athletes
Authors: Aloosh Mehdi , Leclerc Suzanne , Long Stephanie , Zhong Guowei , Brophy James M. , Schuster Tibor , Steele Russell , Shrier Ian
Published: July 2019

Background: Vision tests are increasingly being suggested for use in concussion management and baseline testing. Concussions, however, often occur months after baseline testing and reliability studies generally examine intervals limited to days or one week. Therefore, our objective was to determine the one-year test-retest reliability of these tests.

Methods: We assessed one-year test-retest reliability of ten vision tests in elite Canadian athletes followed by the Institut National du Sport du Quebec. We included athletes who completed two baseline (preseason) annual evaluations by one clinician within 365±30 days. We excluded athletes with any concussion or vision training in between the annual evaluations or presented with any factor that is believed to affect the tests (e.g. migraines, etc.). Data were collected from clinical charts. We evaluated test-retest reliability using Intraclass Correlation Coefficient (ICC) and 95% limits of agreement (LoA).

Results: We examined nine female and seven male athletes with a mean age of 22.7 (SD 4.5) years. Among the vision tests, we observed excellent test-retest reliability in Positive Fusional Vergence at 30cm (ICC=0.93) but this dropped to 0.55 when an outlier was excluded. There was moderate reliability in Negative Fusional Vergence at 30cm (ICC=0.78), Phoria at 30cm (ICC=0.68), Near Point of Convergence break (ICC=0.65) and Saccade (ICC=0.56). The ICC for Positive Fusional Vergence at 3m (ICC=0.56) also decreased to 0.45 after removing one outlier. We found poor reliability in Near Point of Convergence (ICC=0.47), Gross Stereoscopic Acuity (ICC=0.03) and Negative Fusional Vergence at 3m (ICC=0.0). ICC for Phoria at 3m was not appropriate because scores were identical in 14/16 athletes. 95% LoA of the majority of tests were ±40% to ±90%.

Conclusions: Four tests had moderate one-year test-retest reliability. The remaining tests had poor reliability. The tests would therefore be useful only if concussion has a moderate-large effect on scores.
Public health research needs for molecular epidemiology and to emphasize homeostasis – could the omnipotent endopeptidase inhibitor α-2-macroglobulin be a meaningful biomarker?
Authors: Schelp Frank Peter , Kraiklang Ratthaphol , Muktabhant Benja , Chupanit Pornpimon , Sanchaisuriya Pattara
Published: July 2019

Public health authorities in low- and middle-income countries face dramatic challenges in handling rapidly increasing non-communicable diseases (NCDs), due to the epidemiological- and particularly nutritional transition. Among major reasons for the development of NCDs are smoking and alcohol, but overnutrition and obesity are also major threats to population health. Obesity is related to diabetes and cancer, but also has a genetic background. It is difficult to recommend a healthy nutrition. This is because of conflicting nutritional conceptions, and given the complexity of human metabolism understanding this topic can be difficult for the laymen.  Public health measures advocating physical activity and refraining from high intake of energy, sugar and soft drinks need to be enhanced by supporting the ‘intrinsic motivation’ to preserve a good health. The mission of public health should be to increase awareness about the complexity of human metabolism, and the involvement of genetic and epigenetics in health and diseases. To maintain homeostasis, means to keep an optimal relationship between catabolism and synthesis, seems to be of particular interest. Preconditions for this is, that public health institutions within the administration- and academic sector follow up developments in life science and molecular biology and conduct population-based research making use of molecular epidemiology, especially those related to key metabolic steps and maintenance of ‘homeostasis’, in balancing catabolism and anabolism. A prospective biomarker for this situation might be α-2-macroglobulin.
Embedded FFT with dsPIC30F4013
Authors: Setiawan Rachmad
Published: July 2019

FFT-based digital spectral analyzer has become more and more widely used as a result of the development of Digital Signal Processing (DSP) techniques. Modern Analog-to-Digital Converters (ADC) and processors have made it possible to make fast measurements with a limited number of hardware. In this paper, a design of a simple low-cost FFT-based digital spectrum analyzer was presented. The author discusses the design of each components of the system in qualitatively and quantitatively. The report presents the whole system design in detail which contains filter design, micro-controller design and UART transmission design. Some satisfying measurement result of the system were presented in the paper. The system can provide fast measurement with good accuracy. But the measured result has a limited range and resolution of the display is not very high. At last, the advantages and disadvantages of the system was discussed which is considered as guidelines for further work.
Analysis and Dynamic Routing Implementation of Hierarcical Healthcare Referral System
Authors: Alfathdyanto Khairurizal
Published: July 2019

Abstract—Hierarchical Healthcare Referral System (HHRS) is implemented by National Insurance Providing Agency (BPJS) as part of the healthcare insurance policies. Patients who want to get health insurance in a hospital should get a referral from the community health center in which they are registered. Congestion of patients happens in certain hospital as there is no policy implemented to govern the referral system. In this paper, HHRS is modeled as a network of queuing system and is analyzed for its queue performances. Analysis of queuing network performances shows the influence patient preferences to buildup congestion of patients in hospitals. Referral is then controlled by means of dynamic routing with considering patient preferences. Estimation of arrival rate is done with hypercube queuing theory which concerns user preference. Simulation shows that patient preferences affect the arrival rate at each hospital, the application of dynamic routing can reduce the maximum utility and reduce the average waiting time, prioritization of patients improve dynamic routing performance on systems with a high workload.Keywords—dynamic routing; hierarchical healthcare referral system; patient priority; queueing networks;
Quality Assessment of 12 Lead ECG Signals based on Beat Detection Pattern
Authors: Yazid Muhammad
Published: July 2019

Abstract—This paper proposed a new method for assessing signal quality from 12 lead ECG signal. The proposed method can be applied to incoming ECG data stream in one pass, does not involve computatively expensive filtering and does not require large memory space, which makes it especially useful for use in mobile device based ECG signal acquisition. The proposed method is verified on PhysioNet/Computing in Cardiology Chal- lenge 2011 12 lead ECG signals database, achieving a result of 89.98 percent accuracy when tested against the training dataset, and 87.4 percent accuracy when tested against the test data set.
Comparison of Gradient Estimation in Cooperative Multi-Agent Source Seeking
Authors: Sahal Mochammad
Published: July 2019

Agent-based source seeking problem is addressed in this paper. This problem is relevant in, e.g., in hazardous gas leak in a chemical disaster.  In the cooperative search, agents develop a formation to effectively search the source by communicating one to another via a communication topology. The source, or the search target, is represented by a scalar field y which might describe a temperature level, hazardous concentration of substances or vapor. Every agent has the information on its own position and the value of y at any instance. The agents are identical modeled as single and double integrator. Consensus filter is used to control the agent formation and comparison three types of gradient estimation are employed to search the source.  Experiments show that the proposed schemes give good performance to solve cooperative search for source seeking problem
Measurement of Usability for Multimedia Interactive Learning Based on Website in Mathematics for SMK
Authors: Sukardjo Moch , Sugiyanta Lipur
Published: July 2019

Web usability, if evaluation done correctly, can significantly improve the quality of the website. Website containing multimedia for education shoud apply user interfaces that are both easy to learn and easy to use. Multimedia has big role in changing the mindset of a person in learning. Using multimedia, learners get easy to obtain information, adjust information and empower information. Therefore, multimedia is utilized by teachers in developing learning techniques to improve student learning outcomes. For students with self-directed learning, multimedia provides the ease and completeness of the courses in such a way that students can complete the learning independently both at school and at home without the guidance of teachers. The learning independence takes place in how students choose, absorb information, and follow the evaluation quickly and efficiently. The 2013 Curriculum 2013 for Vocational High School (SMK) requires teachers to create engaging teaching and learning activities that students enjoy in the classroom (also called invitation learning environment). The creation of learning activity environment is still problem for most teachers. Various researches reveal that teaching and learning activities will be more effective and easy when assisted by visual tools. Using multimedia, learning material can be presented more attractively that help students understand the material easily. The opposite is found in the learning activity environment who only rely on ordinary lectures. Usability is a quality level of multimedia with easy to learn, easy to use and encourages users to use it. The website Multimedia Interactive Learning for Mathematics SMK Class X is targeted object. Usability website in Multimedia Interactive Learning for Mathematics SMK Class X is important indicators to measure effectiveness, efficiency, and student satisfaction to access the functionality of website. This usability measurement should be done carefully before the design is implemented thoroughly. The only way to get test with high quality results is to start testing at the beginning of the design process and continuously testing each of the next steps. This research performs usability testing on of website by using WAMMI criterion (Website Analysis and Measurement Inventory) and will be focused on how convenience using the website application. Components of Attractiveness, Controllability, Efficiency, Helpfulness, and Learnability are applied. The website in Multimedia Interactive Learning for Mathematics SMK Class X can be in accordance with the purpose to be accepted by student to improve student learning outcomes. The results show that WAMMI method show the usability value of Multimedia Mathematics SMK Class X is about from 70% to 90%.
Impact of Shape and Total of Particle to Characteristics of Partial Discharge and Breakdown Voltage on Oil Insulation in Uniform Field
Authors: Fahmi Daniar , Negara I Made Yulistya , Wahyudi R. , Asfani Dimas Anton , Setyawan Made Yudhi , Wahyudi Mochammad
Published: July 2019

Oil insulation is one of the insulation medium types commonly used in high voltage apparatus. This insulation is to separate between the conductive part and non-conductive part. However, oil insulation can experience decreasing of dielectric strength. It may be caused by the presence of solid particles. Therefore, the testing was conducted to obtain the effect of solid particles to characteristics of partial discharge and breakdown voltage of oil insulation. The results generally proved that the existence of solid particles can reduce the breakdown voltage value of oil insulation. In addition, the solid particles led to two types of corona on oil insulation, namely positive and negative corona.
Dynamic Economic Dispatch On Micro Grid Electrical Systems Using Quadratic Programming
Authors: Suryoatmojo Heri
Published: July 2019

Currently the needs of electric power increased rapidly along with the development of technology. The increase in power requirements is contrary to the availability of sources of energy depletion of oil and coal. This problem affects the national electrical resistance. To meet the needs of large electric power with wide area coverage is required small scale distributed power generation. This distributed generation (DG) of renewable energy sources sought to minimize the use of energy resources such as oil and coal and connected to the micro grid and use the battery as a power balance. Because of there are many DGs and the use of batteries, therefore it is important to determine the optimal power generation of each plant as well as the use of battery based on the optimal capacity so that requirement of electric power can be met with minimal cost each time. This optimization is known as Dynamic Economic Dispatch. In this study, the methods of Quadratic Programming is required to solve the optimization problem.
Perancangan Aplikasi Email Menggunakan Algoritma Caesar CIPHER dan Base64
Authors: Nurani Dwi
Published: July 2019

Send news or documents into individual or group communication media. The nature of news or documents are also used to be very secret. Increasingly sophisticated technology makes it increasingly easy to send a message or document. For example, in the advancement of the internet many parties that provide email management services, from sending or receiving also in terms of archiving. Convenience offered technology is not no risk. News or documents sent over the Internet are vulnerable to crime. In order for news or document can be up to the recipient safely and intact then takes the role of cryptography. Cryptography is the science to encrypt a message to make it more secure. In this study, using algorithms and Base64 Cipher Caesar. Caesar algorithm is an algorithm that is old and easily. While Base64 using ASCII format. So that the two algorithms can be used as it is complex. As a result, the security level is higher than not using cryptography. The encryption process and decryption not complicated and does not require a long time. If there are those who are not responsible to know the content of news or documents then he should know the key to reading and ensured key that only the sender and receiver know.
A Usage of McCall's Software Quality Analysis on the Bonus System of PT Surya Pratama Alam
Authors: Siregar Maria Ulfah , Arif Ahmad Hasan
Published: July 2019

This research is to analyse the software quality of the Bonus System of PT Surya Pratama Alam Yogyakarta. The goal of this study is to determine the level of users’ satisfaction in the use of the system. Method of analysis used is McCall method which is based on operation products with usability factors. The metrics used are Operability metrics and Training metrics. In the operability metrics, the researchers refer to the J.R. Lewis Questionnaires.  Based on the conducted research, researchers can state that the results of software quality measurements of the Bonus System of PT Surya Pratama Alam Yogyakarta is 74.72 % with standard deviation ±14.39 % for Operability metrics and 4.41 seconds with standard deviation ± 1.36 seconds for Training metrics. Based on these two metrics, it can be concluded that the Bonus System of PT Surya Pratama Alam Yogyakarta already has good usability value.
Sistem Otomatisasi Kumbung Jamur Berbasis Raspberry PI
Authors: Iskandar Dadang
Published: July 2019

Budidaya jamur mempunyai kesulitan tersendiri yaitu harus menjaga suhu dan kelembaban pada rentang tertentu. Ruang hidup ideal bagi pertumbuhan jamur yaitu pada suhu 28-30 derajat Celcius dan kelembaban berkisan 80 – 90 %. Untuk menjaga dalam kondisi ideal diperlukan suatu peralatan yang bias memonitor suhu dan kelembaban ruang serta mengkondisikan supaya terus terjaga pada kondisi ideal.Sistem otomatisasi kumbung berfungsi untuk menjaga kondisi kumbung selalu berada pada kondisi ideal. Untuk membaca kondisi ruang menggunakan sensor kelembaban dan dikendalikan oleh raspberry Pi yang menggerakan actuator berupa pompa kabut.
Kiai Fauzan: Pemikiran dan Peranannya di Kabupaten Jepara 1942-1972
Authors: Dalhar M. , Rochwulaningsih Yety , Puguh Dhanang Respati
Published: July 2019

This study focuses on the life, ideas, and role of Kiai Ahmad Fauzan in developing Islamic teachings and national values. Islam and nationalism are two things that interconnected and not contradictory. In Indonesian history, the two of them caused turmoil, even opposition. The purpose of this study is to prove the return of the Moslem spirit which is in line with the development of local religious leaders, primarily through case studies of local scholars in Jepara, such as Kiai Ahmad Fauzan. This study used a historical method, including heuristics, source criticism, interpretation, and historiography. Kiai Ahmad Fauzan was a leader of the Nahdlatul Ulama (NU) who fought through education and politics to uphold the AhlussunahwalJamaah(Aswaja) ideology in Jepara. Fauzan's Islamic and national ideas can be seen from syair[poems] conveyed to the public. Syairbecame a media for propaganda for Kiai Ahmad Fauzan in spreading the religious understanding of Islam Aswaja. It is delivered to the community as reminder and awareness of harmonious religious and national values. His role in the religious and socio-political fields was seen when Japan began occupying Jepara in 1942. He was the target of arrest because of his role as a cleric. Its leadership formed from religious roles carried out mainly through madrasa and da'wah by traveling from one village to another. Kiai Ahmad Fauzan was involved in socio-religious organizations such as the Indonesian Islamic Assembly (MIAI), Indonesian Muslim Council (Masyumi), and NU, especially during the 1955 elections. Kiai Ahmad Fauzan was also trusted by the government to be the first leader of the Ministry of Religion in Jepara after independence revolution.
Clinical biomarker innovation: when is it worthwhile?
Authors: Kluytmans Anouck , Deinum Jaap , Jenniskens Kevin , van Herwaarden Antonius Eduard , Gloerich Jolein , van Gool Alain J. , van der Wilt Gert Jan , Grutters Janneke P.C.
Published: July 2019

Background

Choosing which biomarker tests to select for further research and development is not only a matter of diagnostic accuracy, but also of the clinical and monetary benefits downstream. Early health economic modeling provides tools to assess the potential effects of biomarker innovation and support decision-making.

Methods

We applied early health economic modeling to the case of diagnosing primary aldosteronism in patients with resistant hypertension. We simulated a cohort of patients using a Markov cohort state-transition model. Using the headroom method, we compared the currently used aldosterone-to-renin ratio to a hypothetical new test with perfect diagnostic properties to determine the headroom based on quality-adjusted life-years (QALYs) and costs, followed by threshold analyses to determine the minimal diagnostic accuracy for a cost-effective product.

Results

Our model indicated that a perfect diagnostic test would yield 0.027 QALYs and increase costs by €43 per patient. At a cost-effectiveness threshold of €20,000 per QALY, the maximum price for this perfect test to be cost-effective is €498 (95% confidence interval [CI]: €275–€808). The value of the perfect test was most strongly influenced by the sensitivity of the current biomarker test. Threshold analysis showed the novel test needs a sensitivity of at least 0.9 and a specificity of at least 0.7 to be cost-effective.

Conclusions

Our model-based approach evaluated the added value of a clinical biomarker innovation, prior to extensive investment in development, clinical studies and implementation. We conclude that early health economic modeling can be a valuable tool when prioritizing biomarker innovations in the laboratory.
Challenges and opportunities for integrating genetic testing into a diagnostic workflow: heritable long QT syndrome as a model
Authors: Lubin Ira M. , Lockhart Edward R. , Frank Julie , See Vincent Y. , Vashist Sudhir , Greene Carol
Published: July 2019

Background

An increasing number of diagnostic evaluations incorporate genetic testing to facilitate accurate and timely diagnoses. The increasing number and complexity of genetic tests continue to pose challenges in deciding when to test, selecting the correct test(s), and using results to inform medical diagnoses, especially for medical professionals lacking genetic expertise. Careful consideration of a diagnostic workflow can be helpful in understanding the appropriate uses of genetic testing within a broader diagnostic workup.

Content

The diagnosis of long QT syndrome (LQTS), a life-threatening cardiac arrhythmia, provides an example for this approach. Electrocardiography is the preferred means for diagnosing LQTS but can be uninformative for some patients due to the variable presentation of the condition. Family history and genetic testing can augment physiological testing to inform a diagnosis and subsequent therapy. Clinical and laboratory professionals informed by peer- reviewed literature and professional recommendations constructed a generalized LQTS diagnostic workflow. This workflow served to explore decisions regarding the use of genetic testing for diagnosing LQTS.

Summary and outlook

Understanding the complexities and approaches to integrating genetic testing into a broader diagnostic evaluation is anticipated to support appropriate test utilization, optimize diagnostic evaluation, and facilitate a multidisciplinary approach essential for achieving accurate and timely diagnoses.
Plasmonic optical tweezers based on nanostructures: fundamentals, advances and prospects
Authors: Kotsifaki Domna G. , Chormaic Síle Nic
Published: July 2019

The ability of metallic nanostructures to confine light at the sub-wavelength scale enables new perspectives and opportunities in the field of nanotechnology. Making use of this unique advantage, nano-optical trapping techniques have been developed to tackle new challenges in a wide range of areas from biology to quantum optics. In this work, starting from basic theories, we present a review of research progress in near-field optical manipulation techniques based on metallic nanostructures, with an emphasis on some of the most promising advances in molecular technology, such as the precise control of single biomolecules. We also provide an overview of possible future research directions of nanomanipulation techniques.
Drawing skills in anatomy education and the millennial learner: A cognitive and metacognitive viewpoint
Authors: Kumar Dinesh , Rajprasath Ramakrishnan
Published: July 2019

Drawing can be a useful tool to elicit student thinking and is a widely-used method for communicating scientific ideas. The task of drawing requires students to identify and recall necessary pieces of information they assimilated over a period of time and construct a mental model. However, millennial generation learners, owing to their immersion in 3D technologies, lack interest in practicing and learning from diagrams. This impairs learning and retention of visually-oriented subjects. In this perspective, we reflect on the cognitive and metacognitive processes associated with drawing to emphasize the important role of drawing in present day anatomy education.
Validação de tecnologia para autocuidado do familiar cuidador de pacientes oncológicos paliativos domiciliares
Authors: Vale Jamil Michel Miranda do , Neto Antônio Corrêa Marques , Santana Mary Elizabeth de , Mendes Clarissa Porfírio
Published: July 2019

Objetivo: validar o conteúdo de uma cartilha para subsidiar o autocuidado de familiares cuidadores de pacientes em cuidados paliativos oncológicos domiciliares. Métodos: estudo de caráter metodológico. Os participantes foram 11 juízes especialistas. Estudo auxiliado por um questionário organizado conforme a escala Likert com itens distribuídos em objetivos, estrutura, apresentação e relevância. A verificação quantitativa dos resultados pautou-se na análise estatística descritiva. Resultados: a validação foi efetivada segundo análise dos juízes, obtendo parâmetro maior que o proposto (0,78) para o índice de validade de conteúdo; os 21 itens ultrapassaram o valor de 80,0%. Conclusão: considera-se que a cartilha está validada e pode promover o autocuidado de cuidadores de adoecidos pelo câncer no domicílio.
Thermodynamic Functions of Fe3B Borides
Authors: Filonenko N.Yu. , Galdina O.M. , Kochenov A.V.
Published: July 2019

In this work we study the structural properties of hypoeutectic and hypereutectic Fe-B alloys, depending on the temperature of heating above the liquidus line and the cooling rate. Experiments were carried out for the Fe-B system alloys with boron content of 2.0 - 4.5 % (wt.), the rest is iron. To determine physical properties of the alloys microstructural and X-ray diffraction analysis were used. It is shown that overheating of the molten alloy to 150 K above the liquidus line and aftercooling leads to complete suppression of the formation of primary iron crystals in the hypoeutectic alloys and partially to suppression of Fe2B formation in the hypereutectic alloys of the Fe-B system. For the first time it is shown that heating of Fe-B hypoeutectic alloys to 150 K above the liquidus line and cooling with a rate of 103 K/s lead to formation of Fe3B boride in as-cast state, which was present in the eutectic colony.
The Mechanisms of Nickel-Iron Spinel Phase Nucleation in Aquous Solutions: Crystal Quasichemical Approach
Authors: Boychuk V. , Kotsyubynsky V. , Bandura K. , Hodlevska M. , Dzundza B. , Khatsevych O.
Published: July 2019

The phenomenological model of nikel-iron spinel nucleation with spinel structure based on the partial charge theory and analysis of hydrolysis and polycondensation processes at the interaction of Fe3+-, Fe2+- and Ni2+- hydroxocomplexes at different pH values of reaction medium was proposed. UV-vis optical spectroscopy was used for verification of the obtained results about the regularities of hydroxocomplexes formation. Crystal quasichemistry approach was applied for nucleation of nikel-iron spinel under the conditions of predomination of different defect types in NixFe3-xO4-δ (δ is oxygen non-stoichiometry) spinel lattice. The analysis of changes in electrical conductivity and lattice parameter of defect nickel-iron spinel as a function of Ni2+ atomic concentration was done for different values of d parameter.
Magnetic Susceptibility of Si0,97Ge0,03 Filamentous Crystals Irradiated by Protons
Authors: Pavlovskyy Yu. , Lytovchenko P. , Ostrovskyy I. , Pavlovska N.
Published: July 2019

The article deals with the filamentous Si0,97Ge0,03 crystals with transverse dimensions of 40 ± 2 μm grown by the method of chemical transport reactions in the closed bromide system using gold as a growth initiator. The focus of research was the influence of proton irradiation with doses up to 1∙1017 p+/cm-2 and the following thermal treatments at temperatures of 200 - 500°C on the magnetic susceptibility of these crystals. The dependence of the magnetic susceptibility on the intensity of the magnetic field of the proton irradiated filamentous Si0,97Ge0,03 crystals is described within the framework of the Langevin atom paramagnetism model and explained by the formation of defects of the vacancy type. The revealed increase in the radiation stability of Si0,97Ge0,03 crystals followed the combined effect of radiation and subsequent thermal treatments.