bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from Molecular Modulation of Estrogen-Induced Apoptosis by Synthetic Progestins in Hormone Replacement Therapy: An Insight into the Women's Health Initiative Study
Authors: Sweeney Elizabeth E. , Fan Ping , Jordan V. Craig
Published: April 2023

Supplementary Figure 1. A. MCF-7:WS8 and MCF-7:5C cells were treated with either vehicle for 72 hours or 1nM E2 for 24 or 72 hours. Cells were then harvested, and ERα, PR, and GR proteins were measured by Western blot. MCF-7:WS8 cells were used as a positive control for PR expression. B. MCF-7:5C cells were treated with vehicle, 1nM E2, 1µM Dex, MPA, or NETA, or combinations of 1nM E2 plus 1µM Dex, MPA, or NETA for two months. Cells were harvested, proteins were extracted, and Western blots for ERα and GR protein levels were performed. β-actin was used as a loading control.
Supplemental Figure S2 from Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
Authors: Tran Hung D. , Luitel Krishna , Kim Michael , Zhang Kun , Longmore Gregory D. , Tran David D.
Published: April 2023

Supplemental Figure S2. Related to Figure 2A-E: SNAIL1 expression in primary breast tumors strongly correlates with increased metastasis in MMTV-neuNT mice
Supplementary Methods from A Hypusine–eIF5A–PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer
Authors: Fujimura Ken , Wright Tracy , Strnadel Jan , Kaushal Sharmeela , Metildi Cristina , Lowy Andrew M. , Bouvet Michael , Kelber Jonathan A. , Klemke Richard L.
Published: April 2023

Contains detailed description of materials and methods.
Supplementary Figures S1-S11 from Distinct Subpopulations of Head and Neck Cancer Cells with Different Levels of Intracellular Reactive Oxygen Species Exhibit Diverse Stemness, Proliferation, and Chemosensitivity
Authors: Chang Ching-Wen , Chen Yu-Syuan , Chou Shiu-Huey , Han Chia-Li , Chen Yu-Ju , Yang Cheng-Chieh , Huang Chih-Yang , Lo Jeng-Fan
Published: April 2023

Supplementary Figures S1-S11. The co-expression profile among ALDH activity, memGrp78 and Glut3 in SAS Sphere cells and cisplatin-resistant (cisPtR) SAS cells was examined by FACS (S1); Single-cell suspension from parental SAS or sphere SAS cells was stained with CellROX Deep Red reagent and DCF (S2); Enrichment of the drug-resistant population after in vitro drug treatment (S3); ROSLow cells were sorted using DCFDA staining from SAS sphere cells (S4); Differentially expressed genes of reactive oxygen species scavenging in Parental cells and Sphere cells under 2, 3, 5, or 9 weeks of cultivation with defined serum-free selection medium were collected and analyzed (S5); Treatment of sphere cells with catalase inhibitor 3AT reduced catalase activity (S6); Combinatorial treatment of ROS scavenger inhibitor and cisplatin induces apoptosis cell death (S7); Knockdown of CAT or SOD2 gene expression diminished spheres-forming capability, stemness marker expression of HN-CICs (S8); Overexpression of CAT in HNCICs promotes stemness properties (S9); Overexpression of CAT in HNSCC under defined serum-free selection medium promotes stemness properties (S10); Cell viability of drugs treated hematopoietic stem cells (S11).
Supp Table S3 from In Vivo Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer
Authors: Santos Mirentxu , Martínez-Fernández Mónica , Dueñas Marta , García-Escudero Ramón , Alfaya Begoña , Villacampa Felipe , Saiz-Ladera Cristina , Costa Clotilde , Oteo Marta , Duarte José , Martínez Victor , Gómez-Rodriguez Ma José , Martín Ma Luisa , Fernández Manoli , Viatour Patrick , Morcillo Miguel A. , Sage Julien , Castellano Daniel , Rodriguez-Peralto Jose L. , de la Rosa Federico , Paramio Jesús M
Published: April 2023

Supp Table S3. Gene Ontology of Biological processes of the downregulated genes in mouse bladder tumors.
Supplementary Methods from Myeloid IKKβ Promotes Antitumor Immunity by Modulating CCL11 and the Innate Immune Response
Authors: Yang Jinming , Hawkins Oriana E. , Barham Whitney , Gilchuk Pavlo , Boothby Mark , Ayers Gregory D. , Joyce Sebastian , Karin Michael , Yull Fiona E. , Richmond Ann
Published: April 2023

Supplementary Methods
Supp Table S11 from In Vivo Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer
Authors: Santos Mirentxu , Martínez-Fernández Mónica , Dueñas Marta , García-Escudero Ramón , Alfaya Begoña , Villacampa Felipe , Saiz-Ladera Cristina , Costa Clotilde , Oteo Marta , Duarte José , Martínez Victor , Gómez-Rodriguez Ma José , Martín Ma Luisa , Fernández Manoli , Viatour Patrick , Morcillo Miguel A. , Sage Julien , Castellano Daniel , Rodriguez-Peralto Jose L. , de la Rosa Federico , Paramio Jesús M
Published: April 2023

Supp Table S11. Gene Ontology of Biological processes of the downregulated genes in human recurrent bladder tumors.
Data Supplement from Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor–Modified T Cells in Solid Tumors
Authors: Nishio Nobuhiro , Diaconu Iulia , Liu Hao , Cerullo Vincenzo , Caruana Ignazio , Hoyos Valentina , Bouchier-Hayes Lisa , Savoldo Barbara , Dotti Gianpietro
Published: April 2023

Supplementary Figure S1. NB cells infected with Ad5ÃŽ?24 do not upregulate GD2, Fas, TRAIL receptors and costimulatory molecules
Data Supplement from Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor–Modified T Cells in Solid Tumors
Authors: Nishio Nobuhiro , Diaconu Iulia , Liu Hao , Cerullo Vincenzo , Caruana Ignazio , Hoyos Valentina , Bouchier-Hayes Lisa , Savoldo Barbara , Dotti Gianpietro
Published: April 2023

Supplementary Figure S4. Growth of CHLA-255 cells in mice inoculated in both flanks
Data Supplement from Armed Oncolytic Virus Enhances Immune Functions of Chimeric Antigen Receptor–Modified T Cells in Solid Tumors
Authors: Nishio Nobuhiro , Diaconu Iulia , Liu Hao , Cerullo Vincenzo , Caruana Ignazio , Hoyos Valentina , Bouchier-Hayes Lisa , Savoldo Barbara , Dotti Gianpietro
Published: April 2023

Supplementary Movie 1A. Control T cell
Supplemental Materials and Methods, Figure Legend, Figures S1-6 from SCCA1/SERPINB3 Promotes Oncogenesis and Epithelial–Mesenchymal Transition via the Unfolded Protein Response and IL6 Signaling
Authors: Sheshadri Namratha , Catanzaro Joseph M. , Bott Alex J. , Sun Yu , Ullman Erica , Chen Emily I. , Pan Ji-An , Wu Song , Crawford Howard C. , Zhang Jianhua , Zong Wei-Xing
Published: April 2023

Supplemental Materials and Methods, Figure Legend, Figures S1-6. Figure S1. SCCA1-expressing MCF10A cells become independent of the hormonal factors. Figure S2. Expression of SCCA1 leads to IL-6 production. Figure S3. The induction of UPR by SCCA1 is dependent on its protease inhibition function. Figure S4. Silencing of ATF6a and PERK leads to decreased IL-6 production and cell proliferation in MDA-MB-231 cells. Figure S5. Silencing of SCCA results in decreased UPR, IL-6 production, and cell growth. Figure S6. Elevated SCCA1 expression leads to UPR and IL-6 production in various cell lines.
Supplementary Script B from Discrepancies in Cancer Genomic Sequencing Highlight Opportunities for Driver Mutation Discovery
Authors: Hudson Andrew M. , Yates Tim , Li Yaoyong , Trotter Eleanor W. , Fawdar Shameem , Chapman Phil , Lorigan Paul , Biankin Andrew , Miller Crispin J. , Brognard John
Published: April 2023

Groovy program script used to make the 568 cell line comparison
Supplemental Methods and Legends from Phosphoinositide Protein Kinase PDPK1 Is a Crucial Cell Signaling Mediator in Multiple Myeloma
Authors: Chinen Yoshiaki , Kuroda Junya , Shimura Yuji , Nagoshi Hisao , Kiyota Miki , Yamamoto-Sugitani Mio , Mizutani Shinsuke , Sakamoto Natsumi , Ri Masaki , Kawata Eri , Kobayashi Tsutomu , Matsumoto Yosuke , Horiike Shigeo , Iida Shinsuke , Taniwaki Masafumi
Published: April 2023

Supplemental Methods and Legends
Supplemental Movie 2 from AXL Inhibition Sensitizes Mesenchymal Cancer Cells to Antimitotic Drugs
Authors: Wilson Catherine , Ye Xiaofen , Pham Thinh , Lin Eva , Chan Sara , McNamara Erin , Neve Richard M. , Belmont Lisa , Koeppen Hartmut , Yauch Robert L. , Ashkenazi Avi , Settleman Jeff
Published: April 2023

Timelapse movie of HeLa cells treated with R428 (1ÃŽÂ¼M).
Supplemental Figures 1-8 from ERK Mutations Confer Resistance to Mitogen-Activated Protein Kinase Pathway Inhibitors
Authors: Goetz Eva M. , Ghandi Mahmoud , Treacy Daniel J. , Wagle Nikhil , Garraway Levi A.
Published: April 2023

Supplemental Figures 1-8. Fig. S1. The landscape of mutations of putative ERK1/2 resistance alleles; Fig. S2. Expression and signaling induced by validated ERK resistance alleles; Fig. S3. ERK2 signaling and kinase activity assays with the ERK inhibitor SCH772984; Fig. S4. Analysis of co-mutated ERK1/2 alterations; Fig. S5. Structural localization of RAF/MEK inhibitor alleles; Fig. S6. Drug sensitivity of non-validating alleles; Fig. S7. Drug sensitivity assays of RAF/MEK inhibitor resistance alleles; Fig. S8. Viability of ERK1/2 resistance alleles in WM266.4 cells
Supplementary Table 2 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: April 2023

XLSX file - 14912KB, Somatic mutations in protein-coding genes identified in 70 CRC cell lines using exome-capture sequencing.
Data Supplement from Ubiquitin-like Protein FAT10 Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Modifying β-Catenin Degradation
Authors: Yuan Rongfa , Wang Kai , Hu Junwen , Yan Chen , Li Ming , Yu Xin , Liu Xiuxia , Lei Jun , Guo Wuhua , Wu Linquan , Hong Kui , Shao Jianghua
Published: April 2023

Supplementary Figure S3. Downregulation of FAT10 inhibited HCC cell migration and invasion by suppressing HOXB9 expression in Huh-7 cells.
Supplementary Figure 5 from The TGFβ–miR200–MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors
Authors: Izumchenko Evgeny , Chang Xiaofei , Michailidi Christina , Kagohara Luciane , Ravi Rajani , Paz Keren , Brait Mariana , Hoque Mohammad O. , Ling Shizhang , Bedi Atul , Sidransky David
Published: April 2023

PDF file - 199KB, RNA was extracted from 18 human NSCLCs and 27 pancreatic directly xenografted low passage tumors. Levels of miR200c were measured by quantitative RT-PCR and mRNA levels of Mig6 and EGFR were determined by Affymetrix expression array. Expression levels of A. miR200c, B. Mig6 mRNA or C. EGFR mRNA transcripts were plotted against erlotinib responsiveness.
Supplemental Figures S1-S3 from Long-Chain Fatty Acid Analogues Suppress Breast Tumorigenesis and Progression
Authors: Gluschnaider Udi , Hertz Rachel , Ohayon Sarit , Smeir Elia , Smets Martha , Pikarsky Eli , Bar-Tana Jacob
Published: April 2023

Supplemental Figures S1-S3. c-Src/STAT3 crosstalk of Met-1 cells (S1); c-Src/STAT3 crosstalk of HCC1954 cells (S2); MEDICA amplifies radiation-suppressed clonogenity of HCC1954 cells (S3).
Supplementary Figure S1 from STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer
Authors: Kharma Budiman , Baba Tsukasa , Matsumura Noriomi , Kang Hyun Sook , Hamanishi Junzo , Murakami Ryusuke , McConechy Melissa M. , Leung Samuel , Yamaguchi Ken , Hosoe Yuko , Yoshioka Yumiko , Murphy Susan K. , Mandai Masaki , Hunstman David G. , Konishi Ikuo
Published: April 2023

Supplementary Figure S1. Microarray gene expression across histological subtypes of endometrial cancers.
Supplemental Information from Ag-Presenting CpG-Activated pDCs Prime Th17 Cells That Induce Tumor Regression
Authors: Guéry Leslie , Dubrot Juan , Lippens Carla , Brighouse Dale , Malinge Pauline , Irla Magali , Pot Caroline , Reith Walter , Waldburger Jean-Marc , Hugues Stéphanie
Published: April 2023

Supplemental Information. Supplemental Materials and Methods Supplemental Fig. 1 : Chimeric mice selectively lacking MHCII expression on pDCs. Supplemental Fig. 2 : Similar T cell proliferation in µMT:WT and µMT pIII+IV-/-:WT chimeric mice. Supplemental Fig. 3 : Selective MHCII abrogation on pDCs in μMT pIII+IV-/-:WT mice does not affect MHCII expression and upregulation in other cell subtypes. Supplemental Fig. 4 : MHCII deficient pDCs exhibit normal TLR responses in vitro. Supplemental Fig. 5 : Vaccination using OVA protein + CpG-B significantly inhibits tumor growth after Ag presentation by pDCs. Supplemental Fig. 6 : Characterisation of in vitro generated Th0 and Th17 OT-II T cells. Supplemental Fig. 7 : Impaired cell migration toward tumor supernatant in mice lacking MHCII on pDCs. Supplemental Fig. 8 : CD8+ T cell depletion in EG7 bearing mice.
Supplementary Materials and Methods from A Small-Molecule Modulator of the Tumor-Suppressor miR34a Inhibits the Growth of Hepatocellular Carcinoma
Authors: Xiao Zhangang , Li Chi Han , Chan Stephen L. , Xu Feiyue , Feng Lu , Wang Yan , Jiang Jian-Dong , Sung Joseph J.Y. , Cheng Christopher H.K. , Chen Yangchao
Published: April 2023

Supplementary Materials and Methods. Description of additional methods and procedures used in the study.
Supplemental Table S1 from H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
Authors: Wu Pei-Chun , Lu Jeng-Wei , Yang Jer-Yen , Lin I-Hsuan , Ou Da-Liang , Lin Yu-Hsiang , Chou Kuan-Hsien , Huang Wen-Feng , Wang Wan-Ping , Huang Yih-Leh , Hsu Chiun , Lin Liang-In , Lin Yueh-Min , Shen C.-K. James , Tzeng Tsai-Yu
Published: April 2023

KMT1E expression in 192 lung cancer as evaluated by tissue microarray-based immunohistochemistry
Supplementary Tables S1-S8 from Targeting the c-Met/FZD8 Signaling Axis Eliminates Patient-Derived Cancer Stem–like Cells in Head and Neck Squamous Carcinomas
Authors: Sun Shuyang , Liu Suling , Duan Sheng Zhong , Zhang Lei , Zhou Henghua , Hu Yongjie , Zhou Xianghui , Shi Chaoji , Zhou Rong , Zhang Zhiyuan
Published: April 2023

Supplementary Tables S1-S8. Clinical and pathologic characteristics of SCCHN patients ; Tumorigenicity of sorted primary SCCHN cells using c-Met and CD44 markers ; The effects of c-Met knockdown on the tumor-initiating capacity of HN-CSCs ; The secondary tumor-initiating ability of cells obtained from the xenografts treated with the indicated agents ; The tumor-initiating capacity of HN-CSCs with Axin or DKK-1 overexpression ; Tumor-initiating ability of HN-CSCs with different treatments ; The target sequence of shRNAs ; Primer sequences for qPCR analyses .
Supplemental Figure S4 from H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
Authors: Wu Pei-Chun , Lu Jeng-Wei , Yang Jer-Yen , Lin I-Hsuan , Ou Da-Liang , Lin Yu-Hsiang , Chou Kuan-Hsien , Huang Wen-Feng , Wang Wan-Ping , Huang Yih-Leh , Hsu Chiun , Lin Liang-In , Lin Yueh-Min , Shen C.-K. James , Tzeng Tsai-Yu
Published: April 2023

ANXA2 is required for rescue filopodia formation in lung cancer cells.
Data Supplement from Novel Drug Candidates for the Treatment of Metastatic Colorectal Cancer through Global Inverse Gene-Expression Profiling
Authors: van Noort Vera , Schölch Sebastian , Iskar Murat , Zeller Georg , Ostertag Kristina , Schweitzer Christine , Werner Kristin , Weitz Jürgen , Koch Moritz , Bork Peer
Published: April 2023

Supplementary Table S3. Metastatic signature.
Supplemental Figure S5 from CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy
Authors: Soto-Pantoja David R. , Terabe Masaki , Ghosh Arunima , Ridnour Lisa A. , DeGraff William G. , Wink David A. , Berzofsky Jay A. , Roberts David D.
Published: April 2023

Supplemental Figure S5. Ratio of Granzyme B gene expression to CD8 alpha gene expression in tumors.
Supplemental Figure S4 from CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy
Authors: Soto-Pantoja David R. , Terabe Masaki , Ghosh Arunima , Ridnour Lisa A. , DeGraff William G. , Wink David A. , Berzofsky Jay A. , Roberts David D.
Published: April 2023

Supplemental Figure S4. Effect of T cell depletion on B16F10 melanoma responses to IR in WT and CD47-null mice.
Supplemental Figure Legend from CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy
Authors: Soto-Pantoja David R. , Terabe Masaki , Ghosh Arunima , Ridnour Lisa A. , DeGraff William G. , Wink David A. , Berzofsky Jay A. , Roberts David D.
Published: April 2023

Supplemental Figure Legend. Legend for Supplemental Figures S1-S5.
Supplementary Figure 6 from Microenvironment-Derived HGF Overcomes Genetically Determined Sensitivity to Anti-MET Drugs
Authors: Pennacchietti Selma , Cazzanti Manuela , Bertotti Andrea , Rideout William M. , Han May , Gyuris Jeno , Perera Timothy , Comoglio Paolo M. , Trusolino Livio , Michieli Paolo
Published: April 2023

Supplementary Fig. 6. HGF-induced activation of the PI3K pathway inversely correlates with response to MET-targeted drugs.
Data Supplement from IL15RA Drives Antagonistic Mechanisms of Cancer Development and Immune Control in Lymphocyte-Enriched Triple-Negative Breast Cancers
Authors: Marra Pierfrancesco , Mathew Sumi , Grigoriadis Anita , Wu Yin , Kyle-Cezar Fernanda , Watkins Johnathan , Rashid Mamunur , De Rinaldis Emanuele , Hessey Sonya , Gazinska Patrycja , Hayday Adrian , Tutt Andrew
Published: April 2023

Supplementary Figure S1. Coordinates of the Human Phospho-Kinase Antibody Array (R and D systems).
Supplementary Figure 2 from Microenvironment-Derived HGF Overcomes Genetically Determined Sensitivity to Anti-MET Drugs
Authors: Pennacchietti Selma , Cazzanti Manuela , Bertotti Andrea , Rideout William M. , Han May , Gyuris Jeno , Perera Timothy , Comoglio Paolo M. , Trusolino Livio , Michieli Paolo
Published: April 2023

Supplementary Fig. 2. HGF sustains HER3-independent PI3K signaling in c-MET-amplified cells exposed to MET tyrosine kinase inhibitors.
Supplementary Figure 1 from Microenvironment-Derived HGF Overcomes Genetically Determined Sensitivity to Anti-MET Drugs
Authors: Pennacchietti Selma , Cazzanti Manuela , Bertotti Andrea , Rideout William M. , Han May , Gyuris Jeno , Perera Timothy , Comoglio Paolo M. , Trusolino Livio , Michieli Paolo
Published: April 2023

Supplementary Fig. 1. HGF protects MET-addicted tumor cells against MET TKI-induced growth inhibition.
Supplementary Figure 2 from Hippo Coactivator YAP1 Upregulates SOX9 and Endows Esophageal Cancer Cells with Stem-like Properties
Authors: Song Shumei , Ajani Jaffer A. , Honjo Soichiro , Maru Dipen M. , Chen Qiongrong , Scott Ailing W. , Heallen Todd R. , Xiao Lianchun , Hofstetter Wayne L. , Weston Brian , Lee Jeffrey H. , Wadhwa Roopma , Sudo Kazuki , Stroehlein John R. , Martin James F. , Hung Mien-Chie , Johnson Randy L.
Published: April 2023

PDF file - 127K, SOX9 is elevated in mouse liver tumors with inactivating Hippo pathway mutations.
Supplementary Figure Legends from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche
Authors: Vadrevu Surya Kumari , Chintala Navin K. , Sharma Sharad K. , Sharma Priya , Cleveland Clayton , Riediger Linley , Manne Sasikanth , Fairlie David P. , Gorczyca Wojciech , Almanza Othon , Karbowniczek Magdalena , Markiewski Maciej M.
Published: April 2023

PDF file - 85KB
Data Supplement from The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF
Authors: Watson Ian R. , Li Liren , Cabeceiras Peter K. , Mahdavi Mozhdeh , Gutschner Tony , Genovese Giannicola , Wang Guocan , Fang Zhuangna , Tepper James M. , Stemke-Hale Katherine , Tsai Kenneth Y. , Davies Michael A. , Mills Gordon B. , Chin Lynda
Published: April 2023

Supplementary Figure 6: RAC1 P29S knockdown increases sensitivity of IGR1 melanoma cell lines to MAPK inhibition.
Supplementary Figure 3 from CD66+ Cells in Cervical Precancers Are Partially Differentiated Progenitors with Neoplastic Traits
Authors: Pattabiraman Chitra , Hong Shiyuan , Gunasekharan Vignesh K. , Pranatharthi Annapurna , Bajaj Jeevisha , Srivastava Sweta , Krishnamurthy H. , Ammothumkandy Aswathy , Giri Venkat G. , Laimins Laimonis A. , Krishna Sudhir
Published: April 2023

Supplementary Figure 3. Papillomavirus genomes up-regulate DNMT1 and CIN-612 cells require maintenance of DNA methylation
Data Supplement from The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF
Authors: Watson Ian R. , Li Liren , Cabeceiras Peter K. , Mahdavi Mozhdeh , Gutschner Tony , Genovese Giannicola , Wang Guocan , Fang Zhuangna , Tepper James M. , Stemke-Hale Katherine , Tsai Kenneth Y. , Davies Michael A. , Mills Gordon B. , Chin Lynda
Published: April 2023

Supplementary Figure 7. RAC1 P29S decreases effect of RAF inhibitor treatment on tumor growth in vivo.
Data Supplement from The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF
Authors: Watson Ian R. , Li Liren , Cabeceiras Peter K. , Mahdavi Mozhdeh , Gutschner Tony , Genovese Giannicola , Wang Guocan , Fang Zhuangna , Tepper James M. , Stemke-Hale Katherine , Tsai Kenneth Y. , Davies Michael A. , Mills Gordon B. , Chin Lynda
Published: April 2023

Supplemental Figure Legends
Supplemental Figure 7 from HTLV-1 bZIP Factor HBZ Promotes Cell Proliferation and Genetic Instability by Activating OncomiRs
Authors: Vernin Céline , Thenoz Morgan , Pinatel Christiane , Gessain Antoine , Gout Olivier , Delfau-Larue Marie-Hélène , Nazaret Nicolas , Legras-Lachuer Catherine , Wattel Eric , Mortreux Franck
Published: April 2023

Supplemental Figure 7. (LNA)-antimiR-17 and (LNA)-antimiR-21 increase the expression of p3'-OBFC2A-WT but not p3'-OBFC2A mut17 and p3'-OBFC2A mut21.
Data Supplement from Molecular Changes in Lobular Breast Cancers in Response to Endocrine Therapy
Authors: Arthur Laura M. , Turnbull Arran K. , Webber Victoria L. , Larionov Alexey A. , Renshaw Lorna , Kay Charlene , Thomas Jeremy S. , Dixon J. Michael , Sims Andrew H.
Published: April 2023

Supplementary Figure 1. ILC-specific and IDC-specific response genes identified from breast cancer cell lines are not significantly changed in response to letrozole in patient tumours. Heatmaps (A), gene set enrichment analysis (B) and specific highlighted genes (C) demonstrate that the reported ILC-specific and IDC-specific genes are not significantly changed between the histological cancer subtypes. Heatmap colours show changes in expression relative to respective patient-matched pre-treatment samples (Red=high, Green=low).
Data Supplement from Molecular Changes in Lobular Breast Cancers in Response to Endocrine Therapy
Authors: Arthur Laura M. , Turnbull Arran K. , Webber Victoria L. , Larionov Alexey A. , Renshaw Lorna , Kay Charlene , Thomas Jeremy S. , Dixon J. Michael , Sims Andrew H.
Published: April 2023

Supplementary Figure Legends
Supplementary Table S1 from MYC Activates Stem-like Cell Potential in Hepatocarcinoma by a p53-Dependent Mechanism
Authors: Akita Hirofumi , Marquardt Jens U. , Durkin Marian E. , Kitade Mitsuteru , Seo Daekwan , Conner Elizabeth A. , Andersen Jesper B. , Factor Valentina M. , Thorgeirsson Snorri S.
Published: April 2023

List of Primers.
Supplementary Figures S1-S7 from MYC Activates Stem-like Cell Potential in Hepatocarcinoma by a p53-Dependent Mechanism
Authors: Akita Hirofumi , Marquardt Jens U. , Durkin Marian E. , Kitade Mitsuteru , Seo Daekwan , Conner Elizabeth A. , Andersen Jesper B. , Factor Valentina M. , Thorgeirsson Snorri S.
Published: April 2023

Upregulation of c-MYC in cancer stem cell enriched populations (S1); The doxycycline (Dox)-controlled mCherry marker expression in c-MYC inducible hepatoma cell lines (S2); The doxycycline (Dox) dose-dependent effects of c-MYC induction on CSC properties (S3); The doxycycline (Dox) dose-dependent effects of c-MYC induction on self-renewal potential (S4); c-MYC switch-on and switch-off effects on self-renewal of PLC cells (S5); Effect of p53 knockdown on self-renewal of hepatoma cell lines with doxycycline (Dox) regulated c-MYC expression (S6); p53 knockdown increases the growth rate of HepG2 cells with doxycycline (Dox) regulated c-MYC expression (S7).
Supplementary Figure S1 from Stress Response Protein Cirp Links Inflammation and Tumorigenesis in Colitis-Associated Cancer
Authors: Sakurai Toshiharu , Kashida Hiroshi , Watanabe Tomohiro , Hagiwara Satoru , Mizushima Tsunekazu , Iijima Hideki , Nishida Naoshi , Higashitsuji Hiroaki , Fujita Jun , Kudo Masatoshi
Published: April 2023

Figure S1. Association between Cirp and TNF-B, IL-17, IL-23, Bcl-xL or Dclk1 in the colonic mucosa of patients with ulcerative colitis (UC). Scatter plot of relative mRNA levels of Cirp and respective genes in human colonic mucosa.
Supplementary Figure Legends from Stress Response Protein Cirp Links Inflammation and Tumorigenesis in Colitis-Associated Cancer
Authors: Sakurai Toshiharu , Kashida Hiroshi , Watanabe Tomohiro , Hagiwara Satoru , Mizushima Tsunekazu , Iijima Hideki , Nishida Naoshi , Higashitsuji Hiroaki , Fujita Jun , Kudo Masatoshi
Published: April 2023

Supplementary Figure Legends
Supplementary movie S1 from IGF2 Preserves Osteosarcoma Cell Survival by Creating an Autophagic State of Dormancy That Protects Cells against Chemotherapeutic Stress
Authors: Shimizu Takatsune , Sugihara Eiji , Yamaguchi-Iwai Sayaka , Tamaki Sakura , Koyama Yuko , Kamel Walied , Ueki Arisa , Ishikawa Tomoki , Chiyoda Tatsuyuki , Osuka Satoru , Onishi Nobuyuki , Ikeda Hiroko , Kamei Junzo , Matsuo Koichi , Fukuchi Yumi , Nagai Toshihiro , Toguchida Junya , Toyama Yoshiaki , Muto Akihiro , Saya Hideyuki
Published: April 2023

Supplementary movie S1
Supplementary Table and Figure Legends from Therapeutic Targeting of BRCA1-Mutated Breast Cancers with Agents That Activate DNA Repair
Authors: Alli Elizabeth , Solow-Cordero David , Casey Stephanie C. , Ford James M.
Published: April 2023

Supplementary Table and Figure Legends. Legend for Supplementary Table S1 and Supplementary Figures S1-S5.
Supplementary Table S1 from Therapeutic Targeting of BRCA1-Mutated Breast Cancers with Agents That Activate DNA Repair
Authors: Alli Elizabeth , Solow-Cordero David , Casey Stephanie C. , Ford James M.
Published: April 2023

Supplementary Table S1. Data obtained from the HT-screen for all 94 hits.
Supplementary Materials from Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4+ T-Cell Responses through the PD-1–PD-L1 Axis
Authors: Ding Zhi-Chun , Lu Xiaoyun , Yu Miao , Lemos Henrique , Huang Lei , Chandler Phillip , Liu Kebin , Walters Matthew , Krasinski Antoni , Mack Matthias , Blazar Bruce R. , Mellor Andrew L. , Munn David H. , Zhou Gang
Published: April 2023

PDF file - 27KB
Supplementary Figures from Inhibiting DX2-p14/ARF Interaction Exerts Antitumor Effects in Lung Cancer and Delays Tumor Progression
Authors: Oh Ah-Young , Jung Youn Sang , Kim Jiseon , Lee Jee-Hyun , Cho Jung-Hyun , Chun Ho-Young , Park Soyoung , Park Hyunchul , Lim Sikeun , Ha Nam-Chul , Park Jong Sook , Park Choon-Sik , Song Gyu-Yong , Park Bum-Joon
Published: April 2023

Supplemental Figure S1. The effect of oncogenes on DX2 expression. Supplemental Figure S2. Oncogenic property of DX2. Supplemental Figure S3. Small cell lung cancer in DX2 and DK transgenic model. Supplemental Figure S4. DX2 suppresses p14/ARF. Supplemental Figure S5. Screening of specific inhibitor of p14/ARF and DX2. Supplemental Figure S6. SLCB050 as specific binding inhibitor of p14/ARF and DX2. Supplemental Figure S7. The effect of SLCB050 on DX2. Supplemental Figure S8. Anti-tumoral effects of SLCB050 in DK mice. Supplemental Figure S9. Diagram for summary.
Supplemental Figure Legends from Vaccine-Elicited CD8+ T Cells Cure Mesothelioma by Overcoming Tumor-Induced Immunosuppressive Environment
Authors: Tan Zhiwu , Zhou Jingying , Cheung Allen K.L. , Yu Zhe , Cheung Ka-Wai , Liang Jianguo , Wang Haibo , Lee Boon Kiat , Man Kwan , Liu Li , Yuen Kwok-Yung , Chen Zhiwei
Published: April 2023

The file contains Figure Legends for Supplemental Figures. 12 figure legends are numbered and placed in order.
Supplementary Figure 3 from Promoting Thiol Expression Increases the Durability of Antitumor T-cell Functions
Authors: Kesarwani Pravin , Al-Khami Amir A. , Scurti Gina , Thyagarajan Krishnamurthy , Kaur Navtej , Husain Shahid , Fang Quan , Naga Osama S. , Simms Patricia , Beeson Gyda , Voelkel-Johnson Christina , Garrett-Mayer Elizabeth , Beeson Craig C. , Nishimura Michael I. , Mehrotra Shikhar
Published: April 2023

Supplementary Figure 3. Rapamycin-preconditioned CD8+ T cells upregulate the levels of antioxidant molecules
Table S1 from RABL6A Promotes G1–S Phase Progression and Pancreatic Neuroendocrine Tumor Cell Proliferation in an Rb1-Dependent Manner
Authors: Hagen Jussara , Muniz Viviane P. , Falls Kelly C. , Reed Sara M. , Taghiyev Agshin F. , Quelle Frederick W. , Gourronc Francoise A. , Klingelhutz Aloysius J. , Major Heather J. , Askeland Ryan W. , Sherman Scott K. , O'Dorisio Thomas M. , Bellizzi Andrew M. , Howe James R. , Darbro Benjamin W. , Quelle Dawn E.
Published: April 2023

Table S1. List of differentially regulated genes caused by RABL6A knockdown (KD), relative to control (CON), in BON-1 PNET cells.
Supplemental Figure S5 from Zfx Facilitates Tumorigenesis Caused by Activation of the Hedgehog Pathway
Authors: Palmer Colin J. , Galan-Caridad Jose M. , Weisberg Stuart P. , Lei Liang , Esquilin Jose M. , Croft Gist F. , Wainwright Brandon , Canoll Peter , Owens David M. , Reizis Boris
Published: April 2023

Overlap ZFX targets from DAOY KD array and ChIP-seq are not significantly enriched in expression arrays from murine ESC and HSC.
Figure S4 from RABL6A Promotes G1–S Phase Progression and Pancreatic Neuroendocrine Tumor Cell Proliferation in an Rb1-Dependent Manner
Authors: Hagen Jussara , Muniz Viviane P. , Falls Kelly C. , Reed Sara M. , Taghiyev Agshin F. , Quelle Frederick W. , Gourronc Francoise A. , Klingelhutz Aloysius J. , Major Heather J. , Askeland Ryan W. , Sherman Scott K. , O'Dorisio Thomas M. , Bellizzi Andrew M. , Howe James R. , Darbro Benjamin W. , Quelle Dawn E.
Published: April 2023

Figure S4. Quantitative RT-PCR showing effective silencing of Rb1 mRNA by Rb1 shRNAs in RABL6A knockdown cells.
Figure S2 from RABL6A Promotes G1–S Phase Progression and Pancreatic Neuroendocrine Tumor Cell Proliferation in an Rb1-Dependent Manner
Authors: Hagen Jussara , Muniz Viviane P. , Falls Kelly C. , Reed Sara M. , Taghiyev Agshin F. , Quelle Frederick W. , Gourronc Francoise A. , Klingelhutz Aloysius J. , Major Heather J. , Askeland Ryan W. , Sherman Scott K. , O'Dorisio Thomas M. , Bellizzi Andrew M. , Howe James R. , Darbro Benjamin W. , Quelle Dawn E.
Published: April 2023

Figure S2. Representative IPA mechanistic network for signaling regulators predicted to contribute to the RABL6A knockdown phenotype.
Supplemental Dataset S2 from Zfx Facilitates Tumorigenesis Caused by Activation of the Hedgehog Pathway
Authors: Palmer Colin J. , Galan-Caridad Jose M. , Weisberg Stuart P. , Lei Liang , Esquilin Jose M. , Croft Gist F. , Wainwright Brandon , Canoll Peter , Owens David M. , Reizis Boris
Published: April 2023

List of conserved ZFX targets from comparison of ZFX knockdown microarray data with ZFX ChIP-seq data from murine ESC and DAOY human MB.
Supplementary Figure 8 from GPER Mediates Activation of HIF1α/VEGF Signaling by Estrogens
Authors: De Francesco Ernestina Marianna , Pellegrino Michele , Santolla Maria Francesca , Lappano Rosamaria , Ricchio Emilia , Abonante Sergio , Maggiolini Marcello
Published: April 2023

PDF file - 161KB, Supplementary Figure S8: Staining of SkBr3 tumor xenografts for CD34 endothelial cell marker.
Data Supplement from TALEN-Mediated Somatic Mutagenesis in Murine Models of Cancer
Authors: Zhang Shuyuan , Li Lin , Kendrick Sara L. , Gerard Robert D. , Zhu Hao
Published: April 2023

Supplementary Figure 1. sequencing data for β-catenin TALEN induced mutations in H2.35 cells
Data Supplement from TALEN-Mediated Somatic Mutagenesis in Murine Models of Cancer
Authors: Zhang Shuyuan , Li Lin , Kendrick Sara L. , Gerard Robert D. , Zhu Hao
Published: April 2023

Supplementary Figure 2. genotyping and sequencing data for Apc TALEN induced mutations in H2.35 cells
Supplementary Figure 3 from Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ
Authors: Ho Ping-Chih , Meeth Katrina M. , Tsui Yao-Chen , Srivastava Bhaskar , Bosenberg Marcus W. , Kaech Susan M.
Published: April 2023

PDF file - 191KB, Supplementary Figure 3. PLX4720 treatment does not alter splenic T lymphocyte population.
Supplementary Figure 2 from Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFNγ
Authors: Ho Ping-Chih , Meeth Katrina M. , Tsui Yao-Chen , Srivastava Bhaskar , Bosenberg Marcus W. , Kaech Susan M.
Published: April 2023

PDF file - 181KB, Supplementary Figure 2. Profile of cytokine-producing ability of intratumoral CD8 T cells in BrafV600E/Pten melanomas.
Data Supplement from High Expression of CAI2, a 9p21-Embedded Long Noncoding RNA, Contributes to Advanced-Stage Neuroblastoma
Authors: Barnhill Lisa M. , Williams Richard T. , Cohen Olga , Kim Youngjin , Batova Ayse , Mielke Jenna A. , Messer Karen , Pu Minya , Bao Lei , Yu Alice L. , Diccianni Mitchell B.
Published: April 2023

CAI2 sequence and features (Supp Table S1); CAI2, ARF and p16 expression in various tumor cell lines and normal cells (Supp Table S2); Morphological assessment of low and high passage NMB7 cells after treatment by serum starvation or RA (Supp Table S3).
Data Supplement from RPA Inhibition Increases Replication Stress and Suppresses Tumor Growth
Authors: Glanzer Jason G. , Liu Shengqin , Wang Ling , Mosel Adam , Peng Aimin , Oakley Greg G.
Published: April 2023

Supplementary Figure S1. Raw counts of a clonogenic assay in UMSCC38 cells treated with HAMNO and HAMNO with etoposide.
Data Supplement from High Expression of CAI2, a 9p21-Embedded Long Noncoding RNA, Contributes to Advanced-Stage Neuroblastoma
Authors: Barnhill Lisa M. , Williams Richard T. , Cohen Olga , Kim Youngjin , Batova Ayse , Mielke Jenna A. , Messer Karen , Pu Minya , Bao Lei , Yu Alice L. , Diccianni Mitchell B.
Published: April 2023

Legend for Supplemental Figures S1-S3.
Supplementary Figure S3 from Myostatin Gene Inactivation Prevents Skeletal Muscle Wasting in Cancer
Authors: Gallot Yann S. , Durieux Anne-Cécile , Castells Josiane , Desgeorges Marine M. , Vernus Barbara , Plantureux Léa , Rémond Didier , Jahnke Vanessa E. , Lefai Etienne , Dardevet Dominique , Nemoz Georges , Schaeffer Laurent , Bonnieu Anne , Freyssenet Damien G.
Published: April 2023

Wild-type and Mstn-/- tumor-bearing mice have similar caloric intakes, indicating that anorexia is not involved in the development of cancer cachexia.
Supplementary Figures 1-6 from Host Deficiency in Caveolin-2 Inhibits Lung Carcinoma Tumor Growth by Impairing Tumor Angiogenesis
Authors: Liu Yajun , Jang Sungchan , Xie Leike , Sowa Grzegorz
Published: April 2023

Supplementary Figures 1-6. Figure S1. Strategy used for targeted deletion of exon 2 and 5'-portion of exon 3 of Cav-2 gene in C57BL6 background Figure S2. Brief characterization of newly generated Cav-2 KO mice in C57BL/6N background Figure S3. Subcutaneous growth of LLC tumors in WT versus Cav-2 KO female mice Figure S4. Subcutaneous growth of B16-F10 tumors in WT versus Cav-2 KO mice Figure S5. MVD within B16-F10 tumors implanted into Cav-2 KO and WT mice Figure S6. Relative mRNA levels for selected angiogenic factors within the earliest palpable LLC tumors
Supplemental Figure S2 from IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia
Authors: Ogawara Yoko , Katsumoto Takuo , Aikawa Yukiko , Shima Yutaka , Kagiyama Yuki , Soga Tomoyoshi , Matsunaga Hironori , Seki Takahiko , Araki Kazushi , Kitabayashi Issay
Published: April 2023

Flow cytometric analysis of lineage and LSC markers in NIDF-AML cells.
Supplementary Figure 2 from LASP1 Is a HIF1α Target Gene Critical for Metastasis of Pancreatic Cancer
Authors: Zhao Tiansuo , Ren He , Li Jing , Chen Jing , Zhang Huan , Xin Wen , Sun Yan , Sun Lei , Yang Yongwei , Sun Junwei , Wang Xiuchao , Gao Song , Huang Chongbiao , Zhang Huafeng , Yang Shengyu , Hao Jihui
Published: April 2023

HIF-1α protein expression in CFPAC-1 cell transfected with negative control siRNA (siNC) and HIF-1α siRNA (si HIF-1α#1-3) (50 nM) for 48 hours determined by Western blot. β-actin was used as a loading control.
Supplemental Figure 7 from A Systematic Analysis Reveals Heterogeneous Changes in the Endocytic Activities of Cancer Cells
Authors: Elkin Sarah R. , Bendris Nawal , Reis Carlos R. , Zhou Yunyun , Xie Yang , Huffman Kenneth E. , Minna John D. , Schmid Sandra L.
Published: April 2023

Supplemental Figure 7: Comparison of internalization and total surface binding of endocytic markers between cluster 1 and cluster 2.
Supplementary Table 3 from PLZF, a Tumor Suppressor Genetically Lost in Metastatic Castration-Resistant Prostate Cancer, Is a Mediator of Resistance to Androgen Deprivation Therapy
Authors: Hsieh Chen-Lin , Botta Ginevra , Gao Shuai , Li Tiantian , Van Allen Eliezer M. , Treacy Daniel J. , Cai Changmeng , He Housheng Hansen , Sweeney Christopher J. , Brown Myles , Balk Steven P. , Nelson Peter S. , Garraway Levi A. , Kantoff Philip W.
Published: April 2023

Supplementary Table 3. KEGG analysis of PLZF-repressed program
Supplemental Figure 2 from A Systematic Analysis Reveals Heterogeneous Changes in the Endocytic Activities of Cancer Cells
Authors: Elkin Sarah R. , Bendris Nawal , Reis Carlos R. , Zhou Yunyun , Xie Yang , Huffman Kenneth E. , Minna John D. , Schmid Sandra L.
Published: April 2023

Supplemental Figure 2: Relationship between endocytic activity and total surface expression of receptors.
Suppl Figure 3 from PLZF, a Tumor Suppressor Genetically Lost in Metastatic Castration-Resistant Prostate Cancer, Is a Mediator of Resistance to Androgen Deprivation Therapy
Authors: Hsieh Chen-Lin , Botta Ginevra , Gao Shuai , Li Tiantian , Van Allen Eliezer M. , Treacy Daniel J. , Cai Changmeng , He Housheng Hansen , Sweeney Christopher J. , Brown Myles , Balk Steven P. , Nelson Peter S. , Garraway Levi A. , Kantoff Philip W.
Published: April 2023

Suppl Figure 3. The impact of PLZF alternations on cell growth
Supplement Table 2 from A Systematic Analysis Reveals Heterogeneous Changes in the Endocytic Activities of Cancer Cells
Authors: Elkin Sarah R. , Bendris Nawal , Reis Carlos R. , Zhou Yunyun , Xie Yang , Huffman Kenneth E. , Minna John D. , Schmid Sandra L.
Published: April 2023

Supplement Table 2: NSCLC cell line properties
Supplementary Figure S2 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Authors: Pommier Roxane M. , Gout Johann , Vincent David F. , Alcaraz Lindsay B. , Chuvin Nicolas , Arfi Vanessa , Martel Sylvie , Kaniewski Bastien , Devailly Guillaume , Fourel Geneviève , Bernard Pascal , Moyret-Lalle Caroline , Ansieau Stéphane , Puisieux Alain , Valcourt Ulrich , Sentis Stéphanie , Bartholin Laurent
Published: April 2023

Inactivation of Tif1γ in primary mouse embryonic fibroblasts rapidly results in cell cycle blockade in G2/M phases, spindle checkpoint activation and mitotic catastrophe events.
Supplemental Figures S1-S7 from A TDO2-AhR Signaling Axis Facilitates Anoikis Resistance and Metastasis in Triple-Negative Breast Cancer
Authors: D'Amato Nicholas C. , Rogers Thomas J. , Gordon Michael A. , Greene Lisa I. , Cochrane Dawn R. , Spoelstra Nicole S. , Nemkov Travis G. , D'Alessandro Angelo , Hansen Kirk C. , Richer Jennifer K.
Published: April 2023

Differentially expressed genes in TNBC cells grown in attached vs. forced suspension conditions (S1); Increasing intracellular and secreted metabolites by unsupervised metabolomic analysis (S2); Increased expression of kynurenine pathway enzymes is unique to TNBC cell lines and facilitates endogenous activation of AhR (S3); AhR pathway components are differentially expressed in attached versus suspended conditions (S4); Analysis of TDO2 Inhibitor GI50 in TNBC cell lines (S5); Knockdown of TDO2 and AhR decrease proliferation of TNBC cells (S6); IDO1 expression in breast cancer clinical samples (S7).
Supplementary Figure 1 from STAT3 Inhibition Enhances the Therapeutic Efficacy of Immunogenic Chemotherapy by Stimulating Type 1 Interferon Production by Cancer Cells
Authors: Yang Heng , Yamazaki Takahiro , Pietrocola Federico , Zhou Heng , Zitvogel Laurence , Ma Yuting , Kroemer Guido
Published: April 2023

Supplementary Figure 1. Effect of DOXO on STAT3 phosphorylation.
Supplementary Figure S1 from Kinome-wide Functional Screen Identifies Role of PLK1 in Hormone-Independent, ER-Positive Breast Cancer
Authors: Bhola Neil E. , Jansen Valerie M. , Bafna Sangeeta , Giltnane Jennifer M. , Balko Justin M. , Estrada Mónica V. , Meszoely Ingrid , Mayer Ingrid , Abramson Vandana , Ye Fei , Sanders Melinda , Dugger Teresa C. , Allen Eliezer V. , Arteaga Carlos L.
Published: April 2023

Supplementary Figure S1. RNAi screen to identify kinases that regulate both ER transcriptional activity and viability of MCF7/LTED cells.
Supplementary Data from MMP16 Mediates a Proteolytic Switch to Promote Cell–Cell Adhesion, Collagen Alignment, and Lymphatic Invasion in Melanoma
Authors: Tatti Olga , Gucciardo Erika , Pekkonen Pirita , Holopainen Tanja , Louhimo Riku , Repo Pauliina , Maliniemi Pilvi , Lohi Jouko , Rantanen Ville , Hautaniemi Sampsa , Alitalo Kari , Ranki Annamari , Ojala Päivi M. , Keski-Oja Jorma , Lehti Kaisa
Published: April 2023

Supplementary Data. Supplementary Materials and Methods and Supplementary Figure Legends
Figure S3 from PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus–Induced Liver Carcinogenesis
Authors: Zhang Hao , Diab Ahmed , Fan Huitao , Mani Saravana Kumar Kailasam , Hullinger Ronald , Merle Philippe , Andrisani Ourania
Published: April 2023

Figure S3: Cell cycle synchronization of 4pX-1 cells
Supplementary References from Cables1 Complex Couples Survival Signaling to the Cell Death Machinery
Authors: Shi Zhi , Park Hae R. , Du Yuhong , Li Zijian , Cheng Kejun , Sun Shi-Yong , Li Zenggang , Fu Haian , Khuri Fadlo R.
Published: April 2023

Supplementary References. References for Supplementary Tables and Figures
Supplemental Figure 3 from Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma
Authors: Doçi Colleen L. , Mikelis Constantinos M. , Lionakis Michail S. , Molinolo Alfredo A. , Gutkind J. Silvio
Published: April 2023

Supplementary Figure 3. Gating strategy for FACS analysis of endothelial cell recruitment within matrigel plugs.
Supplemental Figure Legends from Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma
Authors: Cheng Hanyin , Terai Mizue , Kageyama Ken , Ozaki Shinji , McCue Peter A. , Sato Takami , Aplin Andrew E.
Published: April 2023

Supplemental Figure Legends
Supplemental Figure 5 from Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma
Authors: Cheng Hanyin , Terai Mizue , Kageyama Ken , Ozaki Shinji , McCue Peter A. , Sato Takami , Aplin Andrew E.
Published: April 2023

Supplementary Figure 5: cMET expression by flow and IGF signaling.
Supplemental Figure 3 from Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma
Authors: Cheng Hanyin , Terai Mizue , Kageyama Ken , Ozaki Shinji , McCue Peter A. , Sato Takami , Aplin Andrew E.
Published: April 2023

Supplementary Figure 3: Effects of selumetinib treatment in UM cells.
Supplemental Figure 2 from Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma
Authors: Cheng Hanyin , Terai Mizue , Kageyama Ken , Ozaki Shinji , McCue Peter A. , Sato Takami , Aplin Andrew E.
Published: April 2023

Supplementary Figure 2: Growth factor protection from trametinib in an additional cell line.
Supplementary Table S1 from IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis
Authors: Bartolomé Rubén A. , García-Palmero Irene , Torres Sofía , López-Lucendo María , Balyasnikova Irina V. , Casal J. Ignacio
Published: April 2023

List of antibodies used in the different applications
Supplementary Tables 1 and 2, Figures S1-16 from Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages
Authors: Frankenberger Casey , Rabe Daniel , Bainer Russell , Sankarasharma Devipriya , Chada Kiran , Krausz Thomas , Gilad Yoav , Becker Lev , Rosner Marsha Rich
Published: April 2023

Supplementary Tables 1 and 2, Figures S1-16. Supplementary Table 1: Gene lists from DAVID analysis of genes downregulated in RKIP derived TAMs with a Benjamini p-value < 0.5 Supplementary Table 2: Gene lists from DAVID analysis of genes upregulated in RKIP+CCRL5 derived (rescue) TAMs with a Benjamini p-value < 0.5 Figure S1: Immunoblot validation of RKIP expression in 1833 (BM1), MDA-MB-436, and 4T1.2 cells Figure S2: A schematic describing the method used for RNAseq analysis to compare metastatic BM1 with non-metastatic BM1+RKIP Figure S3: Tumor growth in orthotopic xenograft BM1 tumors, significance compared using a 2-way ANOVA. Figure S4: GO categories enriched in BM1+RKIP tumors from RNAseq analysis. Figure S5: Quantile-quantile plots for all stromal cell types tested between metastatic BM1 and non-metastatic BM1+RKIP tumors. Figure S6: Relative TAM infiltration in MDA-MD-436 tumors determined by %pos staining cells for F4/80. Figure S7: Flow cytometric analysis to determine the purity and heterogeneity of BM1 isolated TAMs. Figure S8: CCL5 levels measured by ELISA from BM1 cells in culture. Figure S9: CCL5 expression by qRT-PCR of MDA-MD-436 and 4T1.2 overexpressing RKIP. Figure S10?: RKIP and CCL5 immunoblotts from 1833 (BM1) tumors overexpressing the vectors shown. Figure S11: Tumor growth, tumor weight, and correlation between tumor weight and TAM infiltration in BM1 tumors treated with the CCR5 inhibitor Maraviroc. Figure S12: Invasion assay for BM1 cells overexpressing RKIP, CCL5, or both. Figure S13: Images of Raybiotech L308 arrays. Figure S14: Gene expression data of TAM secreted factors in human patient data sets. Figure S15: Correlation between CCL5 and TAM secreted factors in human patient data sets. Figure S16: Heatmap identifying data sets where breast cancer metastasis free survival is significantly stratified by classifier
Supplementary Figure S2 from Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy
Authors: Shteingauz Anna , Boyango Ilanit , Naroditsky Inna , Hammond Edward , Gruber Maayan , Doweck Ilana , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure S2. Heparanase provide cells with chemo-resistance.
Supplementary Figure Legends from Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy
Authors: Shteingauz Anna , Boyango Ilanit , Naroditsky Inna , Hammond Edward , Gruber Maayan , Doweck Ilana , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure Legends. Legend for Supplementary Figures S1-S3.
Supplementary Tables S1-S2 from Intracellular Osteopontin Inhibits Toll-like Receptor Signaling and Impedes Liver Carcinogenesis
Authors: Fan Xiaoyu , He Chunyan , Jing Wei , Zhou Xuyu , Chen Rui , Cao Lei , Zhu Minhui , Jia Rongjie , Wang Hao , Guo Yajun , Zhao Jian
Published: April 2023

Supplementary Tables S1-S2. Real-Time PCR Primer Sequences (S1); Antibodies and Recombinant Protein Used in Western Blotting (S2).
Supplementary Figure S2 from Targeting the miR-221–222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma
Authors: Zhao Jian-Jun , Chu Zhang-Bo , Hu Yu , Lin Jianhong , Wang Zhongqiu , Jiang Meng , Chen Ming , Wang Xujun , Kang Yue , Zhou Yangsheng , Chonghaile Triona Ni , Johncilla Melanie E. , Tai Yu-Tzu , Cheng Jin Q. , Letai Antony , Munshi Nikhil C. , Anderson Kenneth C. , Carrasco Ruben D.
Published: April 2023

Supplementary Figure S2. AGO2/RNA immunoprecipitation assay in MM1S cells.