bluuebunny/crossref_metadata_2025 huggingface dataset:
El arte de la palabra en el aula
Authors: Parra Mabel
Published: August 2021

El objetivo de este trabajo es rescatar la retórica clásica y destacarsu importancia en el aula. Este arte de la palabra, que se remonta ala Grecia clásica, se constituye en discurso epistémico que busca la«verdad» con el fin de «enseñar». Los actuales estudios lingüísticos:la teoría de la enunciación, de los actos de habla, de la argumentación,del discurso desde una perspectiva crítica y muchos otros que se relacionancon la retórica, permiten considerar el discurso persuasivoque desarrolla estrategias argumentativas y establece relaciones entreenunciador/enunciatario/os.Desde esta perspectiva, la inclusión de la retórica en el aula es casiobligatoria e impostergable, porque el docente, con una adecuada preparación,puede generar las estrategias para canalizar e incentivar lapráctica retórica desde una perspectiva crítica.

 

ARK: http://id.caicyt.gov.ar/ark:/s22507132/jek0dva6q
Didáctica y juego en la educación superior: configuraciones en la formación docente inicial
Authors: Jorge Navarro Marcelo Gastón
Published: August 2021

La didáctica no puede entenderse como un campo acabado de estudioque brinda recetas o fórmulas para enseñar, sino como un espacio dedebate y diálogo en constante construcción de nuevos conocimientos.Partiendo de esta idea reflexionamos sobre la importancia de la didácticay el juego en la formación docente de grado en la educación superiorcomo forma de trabajo que interpela a la interacción constanteentre docente y alumnos, y donde el papel de estos últimos es la principalfuente de construcción de aprendizajes individuales y colectivos.El objetivo del siguiente ensayo es presentar una variedad de perspectivaspara entender y analizar los procesos didácticos enfocados enaspectos lúdicos desde una visión crítica y reflexiva, que dé una miradaholística a la formación docente para así permitir nuevos debates yampliar el panorama de aplicación de diferentes estrategias y técnicasde enseñanza.

 

ARK: http://id.caicyt.gov.ar/ark:/s22507132/8n1sak4st
N. 31 - EDUCAÇÃO A DISTÂNCIA E A FORMAÇÃO DOCENTE: EXPANSÃO E MERCADORIZAÇÃO
Authors: Almeron Andrews Alves , Portelinha Ângela Maria Silveira
Published: August 2021

A Lei de Diretrizes e Bases da Educação Nacional (LDBEN) n.º 9394/1996 reforça a necessidade da formação em nível superior para os docentes da educação básica, o que suscitou a elaboração de políticas públicas que auxiliem no cumprimento dessa demanda. A modalidade de Educação a Distância (EaD) ganha destaque como meio para atender às exigências da legislação. Os dados do Censo do ensino superior vêm apresentando a ascensão da modalidade, particularmente, nos cursos de licenciatura, com destaque ao Curso de Pedagogia, o que vem permitindo uma aproximação da educação superior ao status de mercadoria. Sendo assim, o objetivo desse estudo é discutir os dados relativos à expansão da EaD, particularmente nos cursos de formação docente no Brasil e região do Sudoeste paranaense, evidenciando as articulações da modalidade com o processo de mercadorização do ensino superior. Os procedimentos metodológicos seguem a pesquisa bibliográfica e análise de dados disponíveis no Censo do Ensino Superior e em plataformas oficiais. Os resultados apontam as contradições presentes em uma modalidade que se pauta nas demandas da era da informação e da comunicação e de um cenário socioeconômico que unifica a formação humana a pressupostos mercadológicos, além de alertar sobre a necessidade de análise dos dados acerca da EaD.
n. 32 - POLÍTICAS PÚBLICAS DA EDUCAÇÃO DE JOVENS E ADULTOS E DA EDUCAÇÃO ESPECIAL NO BRASIL: BREVE CONTEXTUALIZAÇÃO
Authors: Trentin Valéria Becher
Published: August 2021

Este artigo traz uma abordagem da trajetória de escolarização de Jovens e Adultos com deficiência na educação brasileira, onde objetiva-se analisar historicamente a articulação entre as políticas públicas das modalidades de ensino EJA e Educação Especial. Assim, caracteriza-se por uma análise documental sobre o movimento das modalidades de ensino e as políticas públicas que as regem. Foram utilizadas fontes primárias e secundárias de pesquisa a qual abarca o período de 1990 até 2016. Mediante a breve análise constatou-se que a busca por soluções para o analfabetismo e para a inclusão caracteriza-se como um processo de tensões, conflitos e influências.  Observou-se também a ausência de articulação entre as modalidades da EJA e a Educação Especial nas políticas públicas, o que aponta o longo caminho a ser percorrido para que jovens e adultos com deficiência tenham garantido efetivamente o direito a uma educação de qualidade.
Abundance and diversity of insects associated with stored grains and tamarind in Nigeria
Authors: Ojo James Adebayo , Omoloye Adebayo Amos
Published: August 2021

Detailed information on insect pests of stored grains in Nigeria is lacking. A two-year survey was conducted to determine the species composition and abundance of insects associated with maize, millet, rice, sorghum and tamarind in eighteen locations across five agro-ecological zones in Nigeria. Sixteen coleopteran, lepidopteran and hymenopteran species were associated with stored products, with high species richness on cereal grains but low species richness on tamarind. Most of these insects are polyphagous on cereal grains, whereas the tamarind weevil Sitophilus linearis (Herbst, 1797) (Curculionidae), and Caryedon serratus (Oliver, 1790) (Chrysomelidae) were found only on tamarind in this study. The maize weevil Sitophilus zeamais (Motschulsky, 1758), rice weevil Sitophilus oryzae (Linneaus, 1763), lesser grain borer Rhyzopertha dominica (Fabricius, 1792) (Bostrichidae), rusty grain beetle Cryptolestes ferrugineus (Stephens, 1831) (Laemophloeidae) and red flour beetle Tribolium castaneum (Herbst, 1797) (Tenebrionidae) were most abundant on stored grains. The tamarind weevil, C. serratus and the sawtoothed grain beetle Oryzaephilus surinamensis (Linneaus, 1758) (Silvanidae) were most abundant on tamarind. The hymenopterans Theocolax elegans (Westwood, 1874) (Pteromalidae), Anisopteromalus calandrae (Howard, 1881) (Pteromalidae) and Cephalonomia waterstoni (Gahan, 1931) (Bethylidae) were the dominant parasitoids of larvae and pupae of the storage pests. Simpson index of diversity of insect species across locations ranged from low (0.63) to high (0.89).
Implementação e Avaliação de Algoritmos de Ordenação Paralela em MapReduce
Authors: Murta Cristina Duarte , Gonçalves Mariane Raquel Silva , Pinhão Paula de Morais
Published: August 2021

Quantidades cada vez maiores de dados, conhecidas como Big Data, são um fato do mundo real e um desaﬁo em termos de processamento de dados. Ordenação é uma das tarefas mais comuns em computação e ordenar grandes massas de dados é uma necessidade em vários processos. O modelo de programação paralela MapReduce tem sido amplamente adotado para processar dados em larga escala em agrupamentos de computadores. Apresentamos neste artigo a implementação de dois algoritmos paralelos de ordenação, o Quicksort Paralelo e o Ordenação por Amostragem. Ambos foram implementados no ambiente de programação MapReduce/Hadoop e testados quanto ao seu desempenho para ordenar dados distribuídos em várias máquinas. Uma variedade de experimentos revela o comportamento de ambos os algoritmos e indica que o algoritmo Ordenação por Amostragem apresenta melhor desempenho.
Três Novos Métodos de Compressão Código usando Padrões de Blocos e Dicionário Multi-Nível
Authors: Dias Wanderson Roger Azevedo , Moreno Edward David
Published: August 2021

Este trabalho propõe e implementa três novos métodos de compressão de código que são simples e eficientes. No artigo também se discute aspectos da implementação do respectivo hardware descompressor. Além disso, um novo tipo de dicionário, que é dividido em níveis, é introduzido neste artigo. O paradigma aplicado para este novo dicionário consiste em armazenar, ao mesmo tempo, instruções unitárias e padrões de blocos encontrados no código do programa, por esta razão, é chamado de Dicionário Multi-Nível. Nas simulações dos algoritmos desenvolvidos, usou-se alguns programas do benchmark MiBench, além de dois processadores embarcados de 32 bits (ARM e MIPS). A taxa média de compressão obtida em nossos métodos chegou a 34,5%. Assim, os algoritmos propostos oferecem uma melhor exploração da tríade compressão-desempenho-consumo.
PBIW-SPARC: Uma Estratégia para Codificação de Instruções em Programas SPARC
Authors: Santos Renato , Marks Renan , Santos Ricardo
Published: August 2021

Esse trabalho apresenta o projeto e desenvolvimento da técnica de codificação de instruções PBIW sobre o conjunto de instruções SPARCv8. A técnica de codificação PBIW foi desenvolvida sobre uma infraestrutura de codificação de instruções em software que mapeia o código gerado pela saída de um compilador no esquema de codificação PBIW projetado para um processador alvo. A adoção da técnica PBIW para codificar programas SPARCv8 é denominada PBIWSPARC. Instruções PBIW-SPARC possuem tamanho de 16 bits e os padrões codificados possuem tamanho de 24 bits. Experimentos estáticos e dinâmicos foram realizados de forma a caracterizar todos os efeitos da codificação PBIW-SPARC no código gerado e no processador alvo. Os resultados encontrados mostram que a codificação PBIW alcança ganhos na razão de compressão e desempenho: até 38% na redução do tamanho do programa e 1,75 de speedup em comparação aos programas SPARCv8.
Reavaliando a Eﬁciência Energética de Memória Transacional em Processadores Convencionais
Authors: Carvalho João P. L. de , Baldassin Alexandro , Azevedo Rodolfo
Published: August 2021

Memória Transacional (TM) é um mecanismo recente de sincronização que objetiva ao mesmo tempo facilitar o desenvolvimento de aplicações concorrentes e fornecer desempenho. A maioria dos trabalhos em TM focam avaliação de desempenho, negligenciando outras métricas como consumo de energia. Trabalhos anteriores analisaram a eﬁciência energética de implementações de TM através de ambientes simulados com modelo de execução simpliﬁcado. Este trabalho apresenta uma reavaliação do consumo de energia e desempenho de uma implementação moderna de memória transacional em processadores convencionais. Será descrito e discutido uma técnica de medição de energia baseada em Registradores Especíﬁcos de Modelo (MSRs), técnica essa utilizada para obter e analisar o consumo energético de aplicações transacionais do benchmark STAMP, bem como de suas respectivas implementações baseadas em travas. Também será discutido o comportamento do consumo de energia e desempenho devido à inﬂuência de diferentes gerenciados de frequência disponíveis em conﬁgurações típicas de sistemas Linux. Nossos resultados mostram que memória transacional em software de fato reduz o consumo de energia quando comparada a implementações baseadas em travas grossas em 7 das 8 aplicações estudadas em um processador Intel® Sandy Bridge™.
Escalonamento Dinâmico Eﬁciente em Arquiteturas Híbridas
Authors: Andrade Guilherme , Ferreira Renato , Ramos Gabriel , Sachetto Rafael , Madeira Daniel , Rocha Leonardo
Published: August 2021

Aplicações que lidam com grandes quantidades de dados em tempo aceitável vem impulsionando o desenvolvimento de novas arquiteturas compostas por diferentes unidades de processamento (UP). Ambientes de execução vem sendo propostos para explorar esses recursos, oferecendo métodos capazes de escalonar tarefas entre diferentes UPs. Embora a maioria das aplicações sejam heterogêneas (tarefas com características distintas), as técnicas atuais focam nessas características de forma isolada, gerando execuções ineﬁcientes. Neste trabalho apresentamos duas novas estratégias de escalonamento, combinando diferentes estratégias, capazes de generalizar em diferentes cenários, sendo até 20% mais eﬁcientes que as técnicas atuais.
Henoch-Schoenlein Purpura Following Severe Acute Respiratory Syndrome Coronavirus-2 Infection: A Case Report
Authors: Soleiman-Meigooni Saeed , Yaghmayee Ramin , Hamidi-Farahani Ramin , Ahmadi Mousa , Taheri Allahyar , Asgari Ali , Soleimani Najafabadi Azam
Published: August 2021

Introduction: As the novel coronavirus pandemic continues to affect people worldwide, immune-mediated inflammatory syndromes related to this virus have been reported. SARS Coronavirus-2 infection disease (COVID-19) may accompany various cutaneous symptoms, such as viral exanthems or wheels. These symptoms may occur at the early course of the disease or after that. Cutaneous symptoms of COVID-19 usually have a favorable outcome. Case Presentation: We presented a rare case of inpatient COVID-19 pneumonia, who developed a purpuric rash, abdominal pain, and hematuria. His dermal histopathological study revealed small-vessel vasculitis. We diagnosed Henoch–Schoenlein purpura based on clinical and histopathological findings and treated him with intravenous dexamethasone followed by oral prednisolone. The purpuric rashes disappeared in two weeks. Conclusions: Cutaneous manifestation of COVID-19 is usually diffuse maculopapular rashes. Other presentations include vesicular rashes and acral cyanosis. Dermal histopathological study in most patients with COVID-19 who developed cutaneous symptoms revealed perivascular inflammation and microthrombus in some cases. Thus, COVID-19 should be considered in any patient with a new onset of cutaneous symptoms.
Examining the Effect of Laparoscopic Cholecystectomy on Coagulation Tests Among Patients Undergoing the Surgery in Ali Ibn Abi Taleb Hospital in Zahedan in 2018
Authors: Shahraki Ahmad Reza , Khazayi Ali Reza , Mohammadi Mahdi , Shahraki Elham , Shahraki Elahe , Niazi Abbas Ali
Published: August 2021

Background: Laparoscopic cholecystectomy, one of the most common elective surgical procedures, is a minimally invasive surgical procedure for patients with gallbladder diseases. Objectives: This study aimed to evaluate the effect of laparoscopic cholecystectomy on coagulation tests among patients undergoing the surgery in Ali Ibn Abi Taleb Hospital in Zahedan. Methods: Following a quasi-experimental design, 21 cases scheduled for laparoscopic cholecystectomy for whatever reasons at Ali Ibn Abi Taleb Hospital in Zahedan (Iran) were selected. To study the serum levels of blood factors, blood samples were collected at three stages, i.e., before the surgery (time point 1), 30 minutes after pumping the carbon dioxide gas into the abdomen (time point 2), and 30 minutes after removing the last port from the abdomen (time point 3). Data were analyzed using repeated measures. Results: According to the findings, laparoscopic cholecystectomy surgery only had a significant effect on the PT coagulation factor at the 99% confidence level. Also, PT was increased and significantly differed at time points 2 (30 minutes after pumping) and 3 (30 minutes after removing the port) compared to time point 1 (30 minutes before the surgery). Conclusions: Generally, it can be argued that despite observing some variations in the PT coagulation factor during the laparoscopic surgery, the INR level did not change. Hence, it can be considered as a safe surgical intervention for renal and liver functions.
Assessment of Clonotypic Rearrangements and Minimal Residual Disease in Lymphoid Malignancies
Authors: Hussaini Mohammad O. , Srivastava Jaya , Lee Lik Wee , Nishihori Taiga , Shah Bijal D. , Alsina Melissa , Pinilla-Ibarz Javier , Shain Kenneth H.
Published: August 2021

Context.—

Measurable (minimal) residual disease (MRD) is an independent prognostic factor for survival outcomes in patients with lymphoid and plasma cell malignancies and has been incorporated into consensus criteria regarding treatment response, strategy, and clinical trial endpoints. clonoSEQ (a next-generation sequencing [NGS]-MRD assay) uses multiplex polymerase chain reaction and NGS to identify clonotypic rearrangements at the immunoglobulin (Ig) H, IgK, IgL, T-cell receptor (TCR)-β, and TCR-γ loci, as well as translocated B-cell lymphoma 1/IgH and 2/IgH sequences for MRD assessment. Additionally, it can be used to confirm diagnoses of cutaneous T-cell lymphoma (CTCL).

Objective.—

To review the technical aspects of our experience using the clonoSEQ Assay in routine clinical practice.

Design.—

In this single-center experience, 390 patients with lymphoid and plasma cell malignancies were assessed with the NGS-MRD Assay at a central laboratory.

Results.—

Median time from arrival of the shipment to initiation of the assay (defined as captured in Adaptive's secure tracking system) was 2.1 hours. Overall, 317 patients had 1 or more samples submitted for sequence identification. Of these, 290 (91.5%) had trackable sequences identified. The median calibration rate of samples by malignancy (where n ≥ 10 samples, excluding CTCL samples) was 88.1%, across a variety of fresh and archived sample sources (177 of 201 samples). TCR-β and/or TCR-γ clonotypes were identified in 40 of 95 samples (42.1%) from 66 patients with suspected CTCL.

Conclusions.—

This NGS-MRD Assay is a valuable and sensitive tool for monitoring MRD in patients with plasma cell and lymphoid malignancies and assisting in the diagnosis of CTCL.
Estratégias grupais para promoção de saúde em universitários
Authors: Souza Deise Coelho de , Favarin Daniela Braga , Scorsolini-Comin Fabio
Published: August 2021

A saúde mental dos estudantes universitários tem representado uma preocupação crescente por parte dos gestores educacionais. Entre as estratégias de atenção a essa população, as intervenções grupais emergem como possibilidade de prestar atendimento a um maior número de jovens, bem como desenvolver aspectos como sociabilidade, aprendizado mútuo e formação de redes de apoio. Este estudo teve por objetivo caracterizar os estudos científicos sobre intervenções grupais realizadas para promoção e prevenção de saúde mental em universitários por meio de uma revisão integrativa da literatura científica nacional e internacional. Foram consultadas as bases/bibliotecas PsycINFO, PubMed, SciELO, LILACS e CINAHL. Foram recuperados 41 artigos publicados entre janeiro de 2009 e dezembro de 2019, a maioria quantitativa. Predominaram estudos com grupos focados em promoção de saúde, sendo os Estados Unidos o país com maior número de pesquisas nesta área. Acerca dos sintomas específicos, o mais comum foi a depressão, ainda que a maioria dos grupos descritos fosse de promoção de saúde mental geral. Os estudos com comparação pré e pós-teste evidenciaram a eficácia da maioria das intervenções grupais. Foi uníssona a recomendação desses estudos acerca da ampliação de programas que incentivem e promovam a saúde mental dos universitários e dos possíveis benefícios oferecidos pelos grupos em ambiente acadêmico.
A Prova Brasil e sua influência na organização do currículo escolar
Authors: Marcolla Valdinei , Serafini Lais Perazzoli
Published: August 2021

Neste texto apresenta-se análise de percepções que professores possuem sobre a influência das avaliações externas, especialmente a Prova Brasil, e quais são as repercussões que essas avaliações provocam na organização do currículo escolar. Na pesquisa foi utilizada a abordagem qualitativa e o método para a coleta de dados foi a entrevista semiestruturada com professoras do ensino fundamental de uma rede municipal de educação do Estado de Santa Catarina. Os resultados demonstraram que, nas percepções de um grupo de professores, as avaliações externas provocam repercussões na organização do currículo escolar, refletem no planejamento docente, diminuem a autonomia do professor, estabelecem um sentimento de competição entre e intraescolas e responsabilizam os professores pelos resultados obtidos nestas avaliações.
Outras margens da revisão de textos: experiências com o literário
Authors: Ribeiro Ana Elisa
Published: August 2021

Neste artigo, abordamos os saberes e as práticas mais específicos da revisão do texto literário, com base em outros trabalhos na área, além de fazermos breve discussão de casos empíricos de revisão de textos literários contemporâneos. Trata-se de um trabalho de cunho ensaístico, que busca defender a ideia de que para um texto literário é necessária uma revisão também literária, isto é, uma prática de revisão mais sensível às questões que tocam esta arte, baseadas em decisões prévias ou acordadas diligentemente com editores/as e autores/as.
A presença social do livro: cultura material e público juvenil
Authors: Salles Livia
Published: August 2021

Neste artigo, pretende-se investigar a importância da materialidade do livro para o público juvenil. Por meio de uma investigação qualitativa feita com jovens leitoras, verificamos que o uso do objeto-livro pode refletir também necessidades sociais, como o pertencimento a um grupo. Como ponto de partida teórico, esse artigo traz os conceitos de sociabilidade e identidade próprias ao universo juvenil, além de refletir sobre as características culturais atribuídas a um objeto, sob a teoria da Cultura Material.
En la lucha final, la arficiosa y fallida novela de Rafael Chirbes
Authors: Llamas Martínez Jacobo
Published: August 2021

Rafael Chirbes se negó a reeditar su novela En la lucha finalpor considerarla fallida, y la editorial Anagrama ha respetado por ahora esa voluntad, de manera que únicamente se ha publicado una edición en 1991. En este artículo se estudian las razones literarias por las que el autor pudo haber tomado esta decisión; muchas de las cuales justifican las convicciones y la trayectoria posterior de Chirbes como escritor.

Rafael Chirbes refused to reissue his novel En la lucha final, considering it failed, and the publishing house Anagrama has so far respected that will. There was only one edition published in 1991. This article studies the literary reasons why the author may have made this decision. Many of them also explain Chirbes’s convictions and career as a writer.
Da etimologia à harmonização neo-latina: motivações gráficas na escritura de a mais encantadora mulher (1903) do romancista brasileiro Gonzaga Filho
Authors: Lima Hozanete
Published: August 2021

Neste trabalho, refletimos sobre a natureza das motivações defendidas pelo romancista brasileiro Gonzaga Filho em sua obra “A Mais Encantadora Mulher”, publicada em 1903. Além das proposições etimológicas, fonéticas e prosódicas, o autor faz uso de uma proposição muito particular, que ele nomeia de harmonia neo-natina. Para o autor, não havia, até a data de publicação de seu romance, no mundo lusófono, nenhum léxico que se impusesse como autoridade a ser seguida. Através da obra de Gonzaga Filho, observamos o comportamento do movimento metaortográfico que se desvelou, no início do século XX, para a constituição ortográfica da língua portuguesa em sincronias passadas e sua importância no processo de estandardização da grafia.

In this work, we reflect on the nature of the motivations defended by the Brazilian novelist Gonzaga Filho in his work “A Mais Encantadora Mulher”, published in 1903. In addition to the etymological, phonetic and prosodic propositions, the author makes use of a very particular proposition, which he names neo-natin harmonization. For the author, there was not, until the date of publication of his novel, in the Portuguese-speaking world, no single lexicon that would impose itself as an authority to be followed. Through the work of Gonzaga Filho, we observe the behavior of the metaorthographic movement that was unveiled, at the beginning of the 20th century, for the orthographic constitution of the Portuguese language in past synchronisms and its importance in the standardization process of spelling
viaje narrativo y el libro de viaje medievales
Authors: Carmona Fernández Fernando
Published: August 2021

El artículo señala la importancia del viaje en el relato literario medieval que responde al despertar sociocultural del siglo xii y caracteriza la llamada novela realista de los siglos xiii y xiv. En particular, al Escoufle de Jehan Renart, a la Manekine de Philippe de Remy y al Roman du comte d’Anjou de Jean Maillart. Novelas coetáneas a la expansión de los libros de viaje y ligadas a estos en la concepción del viaje.

This article points out the importance of travel books in the medieval literary story that responds to the sociocultural awakening of the 12th century and characterizes the realist novel of the 13th and 14th centuries. Particularly noteworthy are Jehan Renart's Escoufle, Philippe de Beaumanoir's Manekine and Jean Maillart's Roman du comte d'Anjou. These novels are contemporary to the expansion of travel books and are connected to the concept of travel.
intensificación en controversias en líneas en español
Authors: Aulit Laetitia
Published: August 2021

Esta investigación presenta un análisis de la intensificación en un corpus de comentarios en español a artículos de prensa digitales sobre la fiesta de Moros y Cristianos, una tradición controvertida en España por el tratamiento de ciertos grupos sociales. Basándose en Albelda y Briz (2020), definimos la intensificación como una estrategia retórico-pragmática de argumentación por la que el hablante refuerza lo dicho y/o su intención para lograr más eficazmente sus metas conversacionales en el discurso. Por eso, este artículo se interesa por las estrategias lingüísticas de intensificación empleadas para posicionarse en estas controversias, tomando en cuenta los contextos comunicativos en los que aparecen, así como las funciones que desempeñan respecto a la argumentación y la imagen. A partir de una metodología adaptada de la metodología desarrollada por Albelda et al. (2014), los resultados muestran que la intensificación aparece principalmente en intervenciones que reaccionan a lo dicho anteriormente de forma general para reforzar la expresión de la postura personal del hablante.

This article presents an analysis of intensification in a corpus of comments in Spanish to digital press articles about the Moors and Christians festival, a tradition that led to controversies in Spain due to its treatment of certain social groups. Based on Albelda and Briz (2020), intensification is defined as a rhetorical and pragmatic strategy of argumentation whereby the speaker strengthens what he says and/or his intention to achieve more efficiently his conversational goals. Therefore, this paper looks into the linguistic strategies of intensification, taking into consideration the specific interactional contexts in which they appear and the functions they carry out regarding argumentation and face. Based on the methodology developed by Albelda and al. (2014), the results show that intensification appears mainly in moves that respond to the entire discussion in order to strengthen the expression of the personal perspective of the speaker.
arte entremesil de Jerónimo de Cáncer y Velasco
Authors: González Maya Juan Carlos
Published: August 2021

Don Jerónimo de Cáncer y Velasco, comediante de la primera mitad del siglo xvii, es uno de esos ingenios que en las monografías, antologías o tratados de teatro breve siempre se destaca por sus habilidades, pero, en cambio, ha sufrido escasa fortuna en las prensas modernas. Motivo por el cual nos ha llegado solo parcial e insuficientemente editado. En el presente artículo se intenta, precisamente por ello, un acercamiento a su arte entremesil a través de una mirada crítica a sus piezas más recónditas o inéditas en honor a sus merecimientos, a partir de la publicación de la primera antología de su teatro breve.

Jerónimo de Cáncer y Velasco, a comedian from the first half of the seventeenth century, is one those witty geniuses that in monographs, anthologies or short theatrical treatises shine for their abilities, though on the contrary he has had little fortune in modern publications. For this reason, he has only reached the public partially or has been insufficiently published. The present article tries, precisely for this reason, to bring to light his work in theatre interlude performances by taking a critical look at his most unexplored or unpublished works, starting with the publication of his first anthology of theatrical pieces.
An erythematous plaque on the nose: What is your diagnosis?
Authors: Rabhi Faten , Frioui Refka , Mansouri Nada , Jabeur Kahena , Dhaoui Abderraouf
Published: August 2021

A 55-year-old male presented to our dermatology department with 3 months history of an asymptomatic and red raised plaque on the nose. There was no history of discoloration of skin prior to the development of this lesion. His only medical history was type 2 diabetes and high blood pressure. He had never undergone radiation therapy. On clinical examination, a well-defined glistening bluish-erythematous plaque 3 * 3 cm was present on the nose which was soft and non-tender (Fig. 1). Nasal mucosa was completely spared. No cervical lymphadenopathy was found. Head and neck examination was unremarkable. A CT scan of head and neck founded a soft tissue mass without infiltration of underlying structures. Figure 1: A well-defined glistening bluish-erythematous plaque 3*3 cm on the nose. DERMOSCOPY FINDINGS The dermoscopy revealed homogeneous pattern with combinations of colors (pinkish, bluish, and violaceous) and whitish veil areas without well-defined vessels or lacunae (Fig. 2). Figure 2: Homogeneous pattern with combinations of colors (pinkish, bluish, and violaceous) and whitish veil areas. HISTOLPATHOLOGY The histological examination of the first biopsy revealed a benign fibtoblastic reaction around normal vessels with fibrin deposits and without nuclear atypia. The second skin biopsy showed anastomosing vascular structures of variable diameter in the dermis, lined by plump endothelial cells with marked cellular, nuclear polymorphism and occasional mitosis, dissecting the collagen bundles (Fig. 3a). On immunohistochemistry, tumor cells expressed CD31, ERG, CD34 and VIII Factor. Ki67 was high in tumor cells (60%) (Fig. 3b). Figure 3: (a) HE x 400. Vascular proliferation with atypical endothelial cells (arrow). (b) IHC x 200, Elevated proliferation index Ki67.
A comparative analysis on question classification task based on deep learning approaches
Authors: Zulqarnain Muhammad , Khalaf Zager Alsaedi Ahmed , Ghazali Rozaida , Ghouse Muhammad Ghulam , Sharif Wareesa , Aida Husaini Noor
Published: August 2021

Question classification is one of the essential tasks for automatic question answering implementation in natural language processing (NLP). Recently, there have been several text-mining issues such as text classification, document categorization, web mining, sentiment analysis, and spam filtering that have been successfully achieved by deep learning approaches. In this study, we illustrated and investigated our work on certain deep learning approaches for question classification tasks in an extremely inflected Turkish language. In this study, we trained and tested the deep learning architectures on the questions dataset in Turkish. In addition to this, we used three main deep learning approaches (Gated Recurrent Unit (GRU), Long Short-Term Memory (LSTM), Convolutional Neural Networks (CNN)) and we also applied two different deep learning combinations of CNN-GRU and CNN-LSTM architectures. Furthermore, we applied the Word2vec technique with both skip-gram and CBOW methods for word embedding with various vector sizes on a large corpus composed of user questions. By comparing analysis, we conducted an experiment on deep learning architectures based on test and 10-cross fold validation accuracy. Experiment results were obtained to illustrate the effectiveness of various Word2vec techniques that have a considerable impact on the accuracy rate using different deep learning approaches. We attained an accuracy of 93.7% by using these techniques on the question dataset.
A prediction and imputation method for marine animal movement data
Authors: Li Xinqing , Sindihebura Tanguy Tresor , Zhou Lei , Duarte Carlos M. , Costa Daniel P. , Hindell Mark A. , McMahon Clive , Muelbert Mônica M.C. , Zhang Xiangliang , Peng Chengbin
Published: August 2021

Data prediction and imputation are important parts of marine animal movement trajectory analysis as they can help researchers understand animal movement patterns and address missing data issues. Compared with traditional methods, deep learning methods can usually provide enhanced pattern extraction capabilities, but their applications in marine data analysis are still limited. In this research, we propose a composite deep learning model to improve the accuracy of marine animal trajectory prediction and imputation. The model extracts patterns from the trajectories with an encoder network and reconstructs the trajectories using these patterns with a decoder network. We use attention mechanisms to highlight certain extracted patterns as well for the decoder. We also feed these patterns into a second decoder for prediction and imputation. Therefore, our approach is a coupling of unsupervised learning with the encoder and the first decoder and supervised learning with the encoder and the second decoder. Experimental results demonstrate that our approach can reduce errors by at least 10% on average comparing with other methods.
DUSP12 regulates the tumorigenesis and prognosis of hepatocellular carcinoma
Authors: Ju Gaoda , Zhou Tianhao , Zhang Rui , Pan Xiaozao , Xue Bing , Miao Sen
Published: August 2021

Background

Dual specificity protein phosphatase (DUSP)12 is an atypical member of the protein tyrosine phosphatase family, which are overexpressed in multiple types of malignant tumors. This protein family protect cells from apoptosis and promotes the proliferation and motility of cells. However, the pathological role of DUSP12 in hepatocellular carcinoma (HCC) is incompletely understood.

Methods

We analyzed mRNA expression of DUSP12 between HCC and normal liver tissues using multiple online databases, and explored the status of DUSP12 mutants using the cBioPortal database. The correlation between DUSP12 expression and tumor-infiltrating immune cells was demonstrated using the Tumor Immune Estimation Resource database and the Tumor and Immune System Interaction Database. Loss of function assay was utilized to evaluate the role of DUSP12 in HCC progression.

Results

DUSP12 had higher expression along with mRNA amplification in HCC tissues compared with those in normal liver tissues, which suggested that higher DUSP12 expression predicted shorter overall survival. Analyses of functional enrichment of differentially expressed genes suggested that DUSP12 regulated HCC tumorigenesis, and that knockdown of DUSP12 expression by short hairpin (sh)RNA decreased the proliferation and migration of HCC cells. Besides, DUSP12 expression was positively associated with the infiltration of cluster of differentiation (CD)4+ T cells (especially CD4+ regulatory T cells), macrophages, neutrophils and dendritic cells. DUSP12 expression was positively associated with immune-checkpoint moieties, and was downregulated in a C3 immune-subgroup of HCC (which had the longest survival).

Conclusion

These data suggest that DUSP12 may have a critical role in the tumorigenesis, infiltration of immune cells, and prognosis of HCC.
Biological Control by Microorganisms
Authors: Harper David R
Published: July 2021

Biological control is the use of natural enemies to reduce the numbers of a damaging organism, which can be anything from a bacterium to a rabbit. Such natural enemies include pathogenic and competitor microorganisms. Biological control agents can be both less toxic and more flexible than chemical pesticides, although given the complexities of biological systems a relatively high level of understanding is required. Although they may be more sympathetically regulated, their high specificity and relative fragility can impose limitations on commercial development. Biological control includes a wide range of approaches, from natural predators to biologically produced molecules. The focus of this article is on microorganisms, including viruses, bacteria, fungi and protozoans. Though many of these cause disease in or poison their target through toxin production, others may act by a different route, for example, by outcompeting the target organism or by excluding it from an ecological niche.

Key Concepts

Biological control is use of material of biological origin to control the numbers or effects of a target organism.

Biological control includes the use of predators, competitors, pathogens and compounds of biological origin.

Microorganisms used include viruses, bacteria, fungi and protozoans. These may cause disease or may compete with or otherwise limit the target organism.

Biological controls tend to be highly specific. Although this generally makes them environmentally benign, it also means that they need to be used in a highly informed way.

Both specificity and the cost and nature of the agents used have limited the use of biological control. All approaches combined account for only around 6% of the global pesticides market, although this figure is rising.
A Highly Ordered, Nanostructured Fluorinated CaP‐Coated Melt Electrowritten Scaffold for Periodontal Tissue Regeneration
Authors: Daghrery Arwa , Ferreira Jessica A. , de Souza Araújo Isaac J. , Clarkson Brian H. , Eckert George J. , Bhaduri Sarit B. , Malda Jos , Bottino Marco C.
Published: August 2021

Periodontitis is a chronic inflammatory, bacteria‐triggered disorder affecting nearly half of American adults. Although some level of tissue regeneration is realized, its low success in complex cases demands superior strategies to amplify regenerative capacity. Herein, highly ordered scaffolds are engineered via Melt ElectroWriting (MEW), and the effects of strand spacing, as well as the presence of a nanostructured fluorinated calcium phosphate (F/CaP) coating on the adhesion/proliferation, and osteogenic differentiation of human‐derived periodontal ligament stem cells, are investigated. Upon initial cell‐scaffold interaction screening aimed at defining the most suitable design, MEW poly(ε‐caprolactone) scaffolds with 500 µm strand spacing are chosen. Following an alkali treatment, scaffolds are immersed in a pre‐established solution to allow for coating formation. The presence of a nanostructured F/CaP coating leads to a marked upregulation of osteogenic genes and attenuated bacterial growth. In vivo findings confirm that the F/CaP‐coated scaffolds are biocompatible and lead to periodontal regeneration when implanted in a rat mandibular periodontal fenestration defect model. In aggregate, it is considered that this work can contribute to the development of personalized scaffolds capable of enabling tissue‐specific differentiation of progenitor cells, and thus guide simultaneous and coordinated regeneration of soft and hard periodontal tissues, while providing antimicrobial protection.
Double‐Sided Graphene‐Enhanced Raman Scattering and Fluorescence Quenching in Hybrid Biological Structures
Authors: Sarau George , Daniel Christoph , Heilmann Martin , Leuchs Gerd , Amann Kerstin , Christiansen Silke H.
Published: July 2021

Due to their large contact and loading surfaces as well as high sensitivities to chemical changes, graphene‐based materials (GBMs) are increasingly being employed into novel nanomedicine technologies. Here biomolecule—monolayer graphene—kidney tissue hybrid structures are studied using mapping micro‐Raman and fluorescence spectroscopies. Because in this configuration graphene interacts with molecules on both sides, a double‐sided graphene‐enhanced Raman scattering (GERS) effect up to ≈10.1 is found for biomolecules adsorbed on graphene and amino acids in the kidney tissue below graphene. Moreover, graphene causes an efficient autofluorescence quenching (FLQ) up to ≈20% emitted by the kidney tissue. Despite the complexity of such layered materials, the intriguing simultaneous occurrence of double‐sided GERS (a new development of GERS) and FLQ phenomena can be well explained by suitable molecular structure and energy level alignment between molecules and graphene. These result in effective charge transfer mediated by non‐covalent interactions as indicated by correlative strain, doping, and defect analyses in graphene based on the Raman data and energy level calculations. Last, the advantages of using graphene over standard photobleaching are demonstrated. This work can be extended to other macromolecular entities toward integrating GBMs in versatile drug delivery, imaging, and sensing devices.
Genesis of Nanogratings in Silica Bulk via Multipulse Interplay of Ultrafast Photo‐Excitation and Hydrodynamics
Authors: Rudenko Anton , Colombier Jean‐Philippe , Itina Tatiana E. , Stoian Razvan
Published: August 2021

Structuring below diffraction limit is key to developing new laser processing technologies as well as to understanding light‐induced processes on mesoscopic scales, notably self‐organization. Here, an advanced numerical perspective on the generation of embedded self‐arranged sub‐wavelength periodic patterns is developed, describing multipulse ultrafast laser interaction with bulk silica glass. Combining light and material dynamics, the approach couples self‐consistently nonlinear propagation, electronic excitation, and fluid dynamics resulting in irreversible phase transitions and localized damage. With increasing the number of applied pulses, the modification changes from localized nanovoids and elongated random nanopatterns toward regular void nanogratings dominantly covering the spot of the focused laser beam. Driven by local and collective scattering events, the order imposed by electric field patterns is then amplified and stabilized by the material response. The model predicts the gradual evolution of the optical properties considering the complex interplay between material arrangement and the electromagnetic field distribution. It allows thus to define light transport optical functions optimizing losses and anisotropic effects.
Carbon dioxide enrichment promoted the growth, yield, and light‐use efficiency of lettuce in a plant factory with artificial lighting
Authors: Chen Danyan , Mei Yanhao , Liu Qi , Wu Yongjun , Yang Zhenchao
Published: August 2021

Lettuce (Latuca sativa L.) is a commercially important crop and a good candidate for production in a plant factory with artificial lighting (PFAL). To explore the influence of CO2 enrichment (eCO2) on lettuce growth, light‐use efficiency (LUE) and various aspects of the growth indicators were specifically assessed. Three CO2 concentrations ([CO2]): ambient CO2 (as the control, approximately 400 μmol mol−1), approximately double the ambient (DA‐CO2, 800 ± 50 μmol mol−1), and approximately quadruple the ambient (QA‐CO2, 1600 ± 50 μmol mol−1) were applied for 30 d. The results indicated that plant height, stem diameter, number of leaves, root length, leaf width, and maximum leaf area were all positively related to [CO2], which illustrated that growth was greater in the treatments with eCO2 than under ambient CO2. The daily average assimilation rate (DAAR), the average dry weight growth rate (GRdw), and yield were also greater for plants grown under DA‐CO2 and QA‐CO2 than under ambient CO2 (DAAR increased by 25.45% and 42.27%, GRdw increased by 28.76 and 37.55%, and yield increased by 33.65 and 44.16%, respectively). Light‐use efficiency increased by 28.51 and 41.12% for DA‐CO2 and QA‐CO2 compared with ambient CO2, respectively. We concluded that eCO2 has the potential to enhance production as well as light utilization in PFAL.
Resilience‐aware design of interconnected supply chain networks with application to water‐energy nexus
Authors: Tsolas Spyridon D. , Hasan M. M. Faruque
Published: July 2021

The effects of natural disasters, pandemic‐induced lockdowns, and other disruptions often cascade across networks. In this work, we use minimum cost of resilience (MCOR) and operation‐based resilience metrics to quantify network performance against single‐connectivity failures and identify critical connections in interconnected networks. MCOR corresponds to the minimum additional infrastructure investment that is required to achieve a certain level of resilience. To guarantee MCOR, we incorporate the metrics in a multi‐scenario mixed‐integer linear program (MILP) that accounts for resilience in the design phase of interconnected networks. The goal is to obtain optimal generation and transportation capacities with flexible operation under all single‐connectivity disruption scenarios. We demonstrate the applicability of our resilience‐aware framework on a water‐energy nexus (WEN) example focusing on grass‐root design and retrofitting. We further apply the framework to analyze a regional WEN and observe that it is possible to achieve “full” resilience in the expense of additional regional investments.
Decarboxylation‐Induced Defects in MOF‐Derived Single Cobalt Atom@Carbon Electrocatalysts for Efficient Oxygen Reduction
Authors: Yuan Shuai , Zhang Jinwei , Hu Linyu , Li Jiani , Li Siwu , Gao Yanan , Zhang Qinghua , Gu Lin , Yang Wenxiu , Feng Xiao , Wang Bo
Published: July 2021

Developing transition metal single‐atom catalysts (SACs) for oxygen reduction reaction (ORR) is of great importance. Zeolitic imidazolate frameworks (ZIFs) as a subgroup of metal‐organic frameworks (MOFs) are distinguished as SAC precursors, due to their large porosity and N content. However, the activity of the formed metal sites is limited. Herein, we report a decarboxylation‐induced defects strategy to improve their intrinsic activity via increasing the defect density. Carboxylate/amide mixed‐linker MOF (DMOF) was chosen to produce defective Co SACs (Co@DMOF) by gas‐transport of Co species to DMOF upon heating. Comparing with ZIF‐8 derived SAC (Co@ZIF‐8‐900), Co@DMOF‐900 with more defects yet one fifth Co content and similar specific double‐layer capacitance show better ORR activity and eight times higher turnover frequency (2.015 e s−1 site−1). Quantum calculation confirms the defects can weaken the adsorption free energy of OOH on Co sites and further boost the ORR process.
Construction of waterborne superhydrophobic coatings with controlled water‐droplet adhesion
Authors: Yang Jixiang , Fan Haoyu , Zhou Yuqian , Liang Huiyun , Zeng Liheng , Xie Dong , Guo Tianying
Published: August 2021

A novel strategy for fabricating waterborne superhydrophobic coatings with controllable adhesive force to water‐droplet has been developed by blending the amphiphilic silica nanoparticles modified using thermally sensitive amphiphilic polymers with polymer latex, which could be applied for self‐cleaning or no loss transfer of microdroplets. And a theoretical analysis of the relationship between the surface chemical composition and the water‐droplet adhesion of the superhydrophobic nanocomposite coating is proposed.
Synthesis and property study of a polyether tercopolymer scale inhibitor with carboxyl and sulfonic acid groups
Authors: Li Hui , Ren Dajun , Zhuang Mengjuan , Wang Zhaobo , Zhang Xiaoqing , Zhang Shuqin , Chen Wangsheng
Published: August 2021

A new environment‐friendly hydrophilic terpolymer of PAA‐AEO‐SAS was synthesized by free radical polymerization using acrylic acid (AA), aliphatic alcohol polyoxyethylene ether (AEO) and sodium allyl sulfonate (SAS). The structure and molecular weight were characterized by FTIR, 1H‐NMR and GPC. The optimal monomer ratio, initiator level, reaction temperature and time for the synthesis of PAA‐AEO‐SAS were determined by the controlled variable method, and the inhibition performance on calcium carbonate (CaCO3) scale at different water bath temperature, pH, Ca2+ concentration and time were investigated by the static scale inhibition method. And the scales were analyzed by XRD and SEM. The results showed that the inhibitor had the best performance when the molar ratio of AA‐AEO/AA/SAS was 1:5:1, initiator was 4 mol%, the polymerization temperature was 85°C, and the reaction time was 2 h. Under the optimal synthesis conditions, the maximum inhibition efficiency was 90% (18 mg/L) and the Mw and Mn of PAA‐AEO‐SAS were 1546 and 1326, respectively. In addition, the surface morphology of calcium scale with the inhibitor was significantly changed from the characterization results. In short, the combination of multiple functional groups allowed the application of PAA‐AEO‐SAS in the complicated and challenging circumstances.