bluuebunny/crossref_metadata_2025 huggingface dataset:
Tuberculosis of Proximal Humerus with Biceps Tendon Involvement - A Rare Case Report
Authors: Mahajan Dr. Neetin P , C Patil Dr. Tushar , Pande Dr. Kartik , Chaudhari Dr. Kunal
Published: February 2022

Introduction: Extra pulmonary TB is caused by dissemination of primary infection through blood and lymph to neighbouring regions like pleura, lymph nodes, bones and joints, where they remain dormant. Reactivation of the disease is caused by disorders of immune system. Skeletal TB consists of 2% of all TB cases and 10-35% of extrapulmonary TB cases. Skeletal TB in humerus are a rare occurrence accounting upto 1-2% of total skeletal TB cases. Here we present a case of proximal humerus tuberculosis which was misdiagnosed and treated as rotator cuff injury by local practitioners and adviced physiotherapy. Case report: The patient is a 16 years old female with humeral head osteomyelitis at bone tendon interface with biceps tendon involvement. We managed the case with MRI followed by CT guided biopsy and anti tubercular regimen was started based on histopathology reports. Patient had resolution of infection with good range of shoulder mobility and satisfactory function. Conclusion: The diagnosis of proximal humerus TB is clinically challenging due to confluence of nonspecific symptoms and X ray findings which misguides clinicians to misdiagnose it as rotator cuff pathology, frozen shoulder, pyogenic osteomyelitis or tumours. This leads to delay in treatment. Probability of skeletal TB should always be kept in mind in such cases, especially in endemic countries which will help in timely diagnosis and treatment.
A Case Report: Solitary Plasmacytoma of bone (SPB) Presenting as an Incidentaloma in a COVID-19 Positive Patient
Authors: Shastry Shastry , A Singla , U Chandel
Published: February 2022

A 70-yr-old covid positive male patient who presented with cough and shortness of breath, upon CT chest found to have features typical of COVID-19 infection and a small mass arising in left 8th rib. A histopathological examination of the mass found to be osseous plasmacytoma, after a PET scan it was confirmed to be a solitary lesion. Bone marrow aspiration cytology showed normal plasma cell count, thus, diagnosed as solitary Plasmacytoma of bone. There was no negative impact on the recovery of the patient by COVID-19 due to solitary Plasmacytoma.
Extra Skeletal Myxoid Chondrosarcoma of the Foot: A Case Report
Authors: Sanaa Sidki , Esdras Zongo Pawendtaoré , Nadia Benchakroun , Tarek Chekrine , Mouna Bourhafour , Zineb Bouchbika , Hassan Jouhadi , Nezha Tawfiq , Souha Sahraoui , Abdellatif Benider
Published: February 2022

Introduction: Extra skeletal myxoid chondrosarcoma is a rare soft tissue tumor. It is a low-grade sarcoma, arising mainly in the deep tissues and musculature of the extremities, with a histological resemblance to its bony counterpart. It accounts for less than 3% of soft tissue sarcomas, and localizes mainly in the upper extremity, shoulder, neck, orbit but also intra-abdominally. It is a tumor with a high metastatic potential and an unfavorable long-term prognosis. Extra skeletal myxoid chondrosarcoma is a tumor occurring in middle-aged patients regardless of gender or race. Treatment is multimodal including surgery, radiation therapy and chemotherapy. Case presentation: A 37-year-old female patient consulted for a subcutaneous swelling on the sole of the left foot opposite the 5th toe; evolving for approximately six years. The clinical examination and the paraclinical work-up revealed a mass that encompassed the diaphysis of the 5th metatarsal with cortical lysis opposite. This mass arrived medially at the contact of the 4th metatarsal without cortical lysis. The extension work-up was unremarkable. The histological, immunohistochemical and molecular biology examination of the surgical biopsy concluded to an extra skeletal myxoid chondrosarcoma. Polychemotherapy with andriamycin and Ifosfamide, surgery and radiotherapy at a dose of 50Gy was performed. Conclusion: Rare tumor and of difficult diagnosis, the key of the diagnosis lies in molecular biology. Survival is often prolonged despite its local aggressiveness.
Left Small Bowel Syndrome A Case Report and Literature Review
Authors: Daouda Diarra , Abdoulfatihi Salihou , Johane Dzota , Dalale Laoudihy , Kamilia Chbani , Siham SALAM , Lahcen EL Ouzidane
Published: February 2022

Left small colon syndrome is a rare cause of neonatal obstruction, favored by the existence of a diabetic mother in 40 to 50% of cases. The diagnosis is evoked by ultrasound and confirmed by an opaque enema with water-solubles. The enema will allow a colonic emptying often accelerating the regression of the digestive symptoms (use of gastrografine if necessary). The prognosis is good with symptomatic and conservative treatment. The meconium plug syndrome can also be compared to this condition, which is also part of the functional occlusive syndromes that resolve.
Posttraumatic Adrenal Hematoma a Case Report and Literature Review
Authors: Daouda Diarra , Abdoulfatihi Salihou , Johane Dzota , Dalale Laoudihy , Kamilia Chbani , Siham Salam , Lahcen El Ouzidane
Published: February 2022

Post-traumatic adrenal hematoma is a difficult to diagnose condition with rare but severe complications. Post-traumatic adrenal hematoma occurs in up to 2% of patients with abdominal trauma. Only CT scans performed during lesion assessments of violent thoracoabdominal trauma can confirm the diagnosis. Symptomatology is often masked by associated visceral or parietal injuries. Standard biological examinations are generally of little help. We describe a case of a 12-year-old child who presented with a right adrenal hematoma after a road traffic accident (MVA), associated with a peritoneal effusion and a fracture of the right sacral fin as well as a fracture of the right pubic ischium.
Spontaneous Coronary Artery Dissection: What Do We Know? A Case Report
Authors: Chachi A. , Belafkih O. , Benbahia A. , Yahya A. Ait , Jourani S. , Eljamili M. , Elkarimi S. , Benzarouel D. , Elhattaoui M.
Published: February 2022

Restlessness occurs during cluster headache attacks and in response to painful stimuli that feel like stemming from an escapable source. Animal experiments show that being repeatedly subjected to restlessness-causing painful stimuli may result in learned helplessness, characterized by passivity and fear in response to pain, and potentially depression. This article reports a patient suffering from chronic cluster headache, whose ictal behaviour had transitioned from restlessness to quiescence and who felt intense fear at the beginning of each attack. We argue that this change may be due to learned helplessness and discuss implications. Learned helplessness might contribute towards a comorbid depression. It should be suspected when the ictal behaviour transitions from restlessness to quiescence, and patients report ictal fear.
Therapeutic Role of Ginger
Authors: Naureen Irum , Saleem Aisha , Zahid Obaida , Din Gulshan Umar , Sadiq Anam , Tul-Kubra Khadija , Rauf Azka , Naqeeb Tahmeena
Published: February 2022

Tahmeena Naqeeb Different plants are used by human to treat different diseases. Ginger is an herb that belongs to Zingiberaceae family. Due to its high chemistry with above 60 compounds, it is used to treat many diseases and is beneficial for health. It is used as antioxidant, antiulcer, anti-cancer, anti-diabetic, anti-inflammatory and used for nausea and vomiting and also improves immune system. Some compounds of ginger areshogaols, gingerols and zingerone. The aim of article is to shows the study of different scientists about the effect of ginger in different disease. Gingerol, shogaol suppress the production of pro inflammatory cytokines such as IL-1, TNF-α, and IL-8.Ginger is productive in glycemic control for people with type 2 diabetes. The active ingredients of ginger include gingerols, which exhibit antioxidant activity. Ginger plays an important role in improving the activity of gastrointestinal track. Due to ginger effect, the level of cardiovascular disorders, digestive problems and diabetes mellitus can decrease.
Hacker, P. M. S. (Peter Michael Stephan), The Moral Powers. A Study of Human Nature. Chichester, West Sussex; Hoboken, NJ, (EE. UU), Wiley-Blackwell, 2021,
Authors: Padilla Gálvez Jesús
Published: February 2022

El libro que reseñamos estudia la naturaleza humana desde una perspectiva
muy amplia al abordar el “potencial moral”. Efectivamente, la expresión inglesa
“moral powers” es compleja de trasladar al castellano ya que hace referencia a la
fuerza moral, aludiendo pues al rendimiento o la potestad moral; así como, la potencia humana y su capacidad moral. Nos encontramos ante un hito que estudia
el valor en la vida y el pensamiento humano, escrito por uno de los pensadores
contemporáneos más activos e importantes del momento. Estamos pues ante una
investigación filosófica sobre las potencialidades y sensibilidades morales de los
seres humanos, del significado de la vida humana y el lugar que ocupa la muerte
en la vida. Se nos presentan unas reflexiones sobre antropología filosófica, es
decir el estudio del marco conceptual mediante el cual pensamos, hablamos e
investigamos acerca del ser humano, entendido en su horizonte social y cultural.
El volumen examina la diversidad de valores en la vida humana y el lugar del valor
moral dentro de las variedades de estos valores. El asunto crucial gira alrededor
de la naturaleza del bien y el mal y la propensión humana a la virtud y al vicio.
Examina las concepciones tradicionales sobre el valor ético y repasa críticamente
los conceptos erróneos que se han ido introduciendo en la filosofía, la psicología
o la neurociencia cognitiva.
SNELLER, Rico, Perspectives on Synchronicity, Inspiration and the Soul. Newcastle: Cambridge Scholars Publishing, 2019
Authors: Bula Caraballo Germán
Published: February 2022

La lectura de libros especializados es, casi siempre, un ejercicio que implica
un cierto grado de redundancia. Para el filósofo de profesión, la lectura de un libro
académico suele implicar el repaso de una buena cantidad de ideas ya conocidas
(a las que se añaden unas cuantas, que constituyen el aporte específico del libro
en cuestión). En este aspecto, el libro de Rico Sneller es una sorprendente excepción: aborda temas bien poco comunes, haciendo uso de un arsenal de referentes
académicos inusuales aunque de muy buen calibre: desde la artista brasilera Lygia
Clark hasta la biología vitalista de Hans Driesch y la Lebensphilosophie de Ludwig Klages, pasando por los sesudos estudios de Max Picard sobre la fisiognomía
HAN, Byung. Ausencia. Acerca de la cultura y la filosofía del Lejano Oriente (Trad. Graciela Calderón). Buenos Aires: Caja Negra, 2019
Authors: Almeyda Sarmiento Juan David
Published: February 2022

Existe dentro del trabajo filosófico de Byung-Chul Han un ejercicio amable
por intentar conciliar dos tradiciones en una hibridación teórico-práctica, sépase,
poner en comparación (en una conversación o una dialéctica) el pensamiento
oriental y el occidental. La lectura apresurada de los haikus ensayísticos de Han
llevan a encasillarlo meramente en las bases de la tradición de Occidente. Los
trabajos sobre el neoliberalismo, el cansancio, la transparencia y lo digital, parten
de bases filosóficas que son comunes a los habitantes de este lado del mundo,
sin embargo, las investigaciones que tiene este mismo autor sobre la tradición
oriental pasan sin pena ni gloria. Ausencia pertenece a esta segunda categoría,
es una obra que parte de una metodología expuesta en el pasado por Han: “el
presente estudio se desarrolla mediante comparaciones (…) Empleamos aquí la
comparación como método que saca a la luz el sentido”1
إدراك شركات صناعة الاسمنت الليبية بأهمية المسؤولية الاجتماعية
Authors: أبوستالة أبوالقاسم
Published: February 2022

يتمثل الهدف الرئيسي لهذه الدراسة في تحديد مستوى أدراك شركات قطاع الاسمنت الليبية بأهمية المسؤولية الاجتماعية. ولتحقيق أهداف الدراسة، تم الاعتماد على المنهج الوصفي التحليلي، وتم تصميم استبانة محكمة ومعدة على قياس (ليكرث الخماسي) كأداة رئيسية لجمع البيانات الاولية والمعلومات اللازمة من مجتمع الدراسة، بالتطبيق على جميع شركات الاسمنت. وقد استهدفت الاستبانة جميع موظفي أقسام المالية والمراجعة الداخلية، ونظراً لصغر حجم مجتمع الدراسة فإن الباحث اعتمد أسلوب المسح الشامل حيث تم توزيع عدد (91) استمارة على جميع أفراد مجتمع الدراسة، وبعد منح المشاركين فترة كافية للإجابة على أسئلة الاستبيان، تم استلام عدد (82) استمارة صالحة للتحليل وبنسبة (%91.11). توصلت الدراسة لعدة نتائج أهمها: وجود إدراك كافي لدى شركات صناعة الاسمنت الليبية بأهمية المسؤولية الاجتماعية. وقد أوصت الدراسة بضرورة القيام بورش عمل وحلقات نقاش حول أهمية المسؤولية الاجتماعية، وأيضا ضرورة إنشاء إدارة خاصة تعنى بالمسؤولية الاجتماعية، والعمل على استصدار دليل يوضح فيه رؤية الشركة، ورسالتها، وأهدافها تجاه المسؤولية الاجتماعية.
الاتجاهات الحديثة لتوظيف وسائل الدفع الالكترونية بالمصارف الليبية في ظل جائحة كوفيد-19
Authors: الزطيف أحمد , ناصف محمد
Published: February 2022

هدفت هذه الدراسة للتعرف على الاتجاهات الحديثة لتوظيف وسائل الدفع الالكترونية بالمصارف الليبية في ظل كوفيد 19. باستخدام المنهج الوصفي التحليلي، تم توزيع (51) استبانة على عينة من فروع المصارف التجارية بمدينة مصراتة، وكذلك عن طريق المقابلة الشخصية لعدد من المسؤولين داخل المصارف عينة الدراسة وتوصلت نتائجها إلى ضعف الاتجاهات الحديثة لتوظيف وسائل الدفع الالكترونية من خلال قصور المصارف الليبية عينة الدراسة في تجسيد الثقافة البيعية وضعف التنويع لوسائل الدفع الالكترونية بهدف التقليل من المخاطر والرفع من مستوي الأمان. لذا يمكن إقرار عدم رفض الفرض الصفري للدراسة مما يعني أنه لا توجد اتجاهات حديثة لتوظيف وسائل الدفع الالكترونية بالمصارف الليبية في ظل كوفيد -19 .
Studying of the degree of resistance of cotton varieties and varieties of the world collection to v. Wilt (wilting) disease
Authors:   Bitki Mühafizə və Texniki Bitkilər Elmi-Tədqiqat İnstitutu aqrar elmlər üzrə elmlər doktoru, professor, Əlirza oğlu Tağıyev Ələddin , Həsən oğlu Məmmədov Oqtay ,   Bitki Mühafizə və Texniki Bitkilər Elmi-Tədqiqat İnstitutu böyük elmi işçi, Kazım qızı Bürcəliyeva Tamara ,   Bitki Mühafizə və Texniki Bitkilər Elmi-Tədqiqat İnstitutu böyük elmi işçi, Qafar qızı Əliyeva Nərgiz ,   Bitki Mühafizə və Texniki Bitkilər Elmi-Tədqiqat İnstitutu böyük elmi işçi
Published: February 2022

Aparılan tədqiqat nəticəsində məlum olmuşdur ki, müsabiqəli və Dövlət sort sınaqlarında öyrənilən perspektivli pambıq sortları arasında V.vilt xəstəliyinə daha az yoluxan pambıq sortları gələcəkdə respublikada rayonlaşdirılması ümidverici hesab edilir. Vilt xəstəliyinə nisbətən davamlı olan Gəncə-212, Gəncə-114, Gəncə 282, Gəncə-110, Gəncə-202, Gəncə-132, Gəncə-103, Gəncə-103 və Gəncə-160 sortları üzrə aparılmış tədqiqatın nəticələri göstərmişdir ki, xəstəliyə yoluxma faizi 10,9-19,3% arasında olmuşdur. Pambığın dünya kolleksiyasının Antep, Karizma, BA-440, Maraş, 71046-68, H-888, Çin-37, N-777, Edessa, Carla sort nümunələrinin vilt xəstəliyinə davamlılıq dərəcəsi 2,6-21,9% arasında olmuşdur. Dünya kolleksiyasının sort nümunələrinin vilt xəstəliyinə yoluxma faizlərinə əsasən məhsul itkisi 0,5-dən 4,8% arasında olmuşdur. Vilt xəstəliyinə az sirayətlənmiş, viltə davamlı pambığın dünya kolleksiyasının birillik sort nümunələrindən seleksiyada başlanğıc material kimi istifadə olunması tövsiyə olunur. Açar sözlər: pambıq, seleksiya, sort, vilt xəstəliyi, süni infeksion vilt fonu, yoluxma dərəcəsi Aladdin Alirza Taghiyev Oktay Hasan Mammadov Tamara Kazim Burjaliyeva Nargiz Gafar Aliyeva Studying of the degree of resistance of cotton varieties and varieties of the world collection to v. Wilt (wilting) disease Abstract In the course of the study, the biological characteristics of cotton, agrotechnical measures, soil and climatic conditions and technological factors that create conditions for a “fibrous coat”, “seed coat” and “seed crumbs” in the fiber were studied. The morphological characteristics of the varieties, the weight of the seed may differ depending on the soil-climatic and agrotechnical conditions, as well as the cultivation conditions. Key words: cotton plant, new varieties of cotton plant, diseases to wilt, the artificial background of inflectional wilt, varietal samples
Digital map models completed on the basis of statistical indicators of anthropogenic transformed landscapes of the Great Caucasus province
Authors:   Bakı Slavyan Universiteti doktorant, Zakir oğlu İbrahimli Kamil
Published: February 2022

Məqalədə Böyük Qafqazın antropogen transformasiya olunmuş landşaftlarının asimmetriya və variasiya əmsallarının rəqəmsal izoxətli xəritə modeli göstərilmişdir. Bu əmsallar bir-biri ilə müqayisə edilmişdir. Bu cür rəqəmsal xəritə modellər landşaft diferensasiyasının öyrənilməsində, kompleks fiziki-coğrafi rayonlaşdırma və digər tədqiqat işlərində istifadə oluna bilər. Açar sözlər: rəqəmsal xəritə model, antropogen transformasiya, landşaft, asimmetriya, variasiya Kamil Zakir İbrahimli Digital map models completed on the basis of statistical indicators of anthropogenic transformed landscapes of the Great Caucasus province Abstract In the article have been shown the models of digital izoline map of coefficient of asymmetry and varition of anthropogenic transformed landscape of the Greater Coucaus. These coefficients have been compared each others. This kind of digital map models can be used study of differentiation landscapes, complex physical and geographical division into districts and important work and research. Key words: digital map model, anthropogenic transformed, landscape, asymmetry, variation
Classification of crimes against international law in the territories of Azerbaijan occupied by Armenia
Authors:   Bakı Dövlət Universiteti  magistrant, Raiq qızı Ağayeva Nərmin
Published: February 2022

Qafqaz regionunu daim gərginlikdə saxlamaq məqsədilə ermənilərin beyninə «Böyük dövlət» yaratmaq ideyası sindromunu həmişə müəyyən dövlətlərin örtülü siyasəti olmuşdur. Odur ki, erməni terroru bu gün də həmin maraqların, «ikili standartların» latent ifadəsinə çevrilmişdir. Rus tarixçisi Nikolay Şavrov «Zaqafqaziyada Rusiya işlərinə yeni təhlükə» adlı kitabında qeyd edir ki, 1864-cü ildə Qafqaz idarələrində çoxluq təşkil edən erməni və gürcülərdə millətçilik fəaliyyəti oyandı. Erməni və gürcü çarlıqlarını yenidən dirçəltmək ideyası Londonda onların rəhbər şəxslərinin beyninə yeridildi. Bu, əslində tarixi torpaqlara malik olmayan ermənilərin Zaqafqaziyada mümkün qədər daha çox ərazi ilhaqına həvəsləndirilməsi idi. Sonralar isə «dənizdən-dənizə Ermənistan» yaratmaq ideyası «Daşnaksütyun» partiyasınınəsas ideyasına çevrildi. 1890-cı ildə Tiflisdə erməni millətçi partiyası kimi yaradılan «Daşnaksütyun» Türkiyə ermənilərinin azad edilməsi, Rusiya və Türkiyə ermənilərinin «Vahid, ümumi «vətəni» — «Böyük Ermənistan» yaradılması kimi avantürist ideya irəli sürərək, təbliğata başlamışlar. Açar sözlər: Dağlıq Qarabağ, hüquqa zidd, təcavüzkar, işğalçı, terror Narmin Raig Aghayeva Classification of crimes against international law in the territories of Azerbaijan occupied by Armenia Summary The syndrome of the idea of creating a «Great State» in the minds of Armenians in order to keep the Caucasus region under constant tension has always been a covert policy of certain states. That is why Armenian terrorism has become a secret expression of these interests, «double standards». Russian historian Nikolai Shavrov, in his book «A New Threat to Russian Affairs in the Caucasus», states that in 1864 the nationalist movement awakened in the Armenians and Georgians, who formed the majority in the Caucasus administrations. The idea of reviving the Armenian and Georgian kingdoms was planted in the minds of their leaders in London. This was actually to encourage the Armenians, who did not have historical lands, to annex as much land as possible in the Caucasus. Later, the idea of creating «Armenia from sea to sea» became the main idea of the Dashnaksutyun party. Founded as an Armenian nationalist party in Tbilisi (Georgia) in 1890, Dashnaksutyun began its propaganda with the adventurous idea of liberating Turkish Armenians and creating a «single, common» homeland» of Russian and Turkish Armenians. Greater Armenia». Key words: Nagorno-Karabakh, illegal, aggressor, occupier, terror
Analyzing the social relations in the “the grapes of wrath
Authors:   Bakı Mühəndislik Universiteti müəllim, İlham qızı Hüseynli Çinarə
Published: February 2022

Məqalə cəmiyyətdə və ailədə qadınların rolundan bəhs edir. Qadın və kişilər bərabər hüquqlu kimi görünsələr də, onlar arasındakı hüquq bərabərsizliyi həllini tapmayan problemə çevrilib. Əlbəttə, əvvəllər qadınlar kişilərlə eyni hüquqlara sahib deyildilər. Amma onların kişilər üzərində böyük rolu var idi. Buna nümunə olaraq Ana Coud obrazını göstərmək olar. O güclü və iradəli qadınları təmsil edir. Məqalə qadınların kişilərlə bərabər niyə eyni hüquqa sahib olmadığını və digər tərəfdən də onların bütün çətinliklərə qarşı necə güclü dayandığını araşdırır. Açar sözlər: Böyük Böhran, miqrant, fermer, torpaq, sahibkar, sosial, iş Chinara Ilham Huseynli Analyzing the social relations in the “the grapes of wrath Summary This article deals with how migrants and farmers were affected as a result of the Great Depression. People had to leave their lands and begin a new journey hoping to find new places to get by and to work. Along this journey, they experienced lots of troubles due to the difficulties caused by the landowners. The novel shows us how cruel a man can be to another man. In the novel, several issues are highlighted, but this article mostly focuses on the social discrimation and its effects. Key words: Great Depression, miqrant, farmer, land, landowner, social, work
DENTISTS’ MOBILE PHONES AS A MEANS OF SPREADING CONDITIONALLY PATHOGENS
Authors: Horzov Liudmyla , Kryvcova Maryna , Kostenko Svitlana , Yurzhenko Anastasiia
Published: February 2022

The aim: The aim of the study was to determine the level of bacterial contamination of mobile phones and watches of dentists.
Materials and methods: The study was conducted at the University Dental Clinic and Microbiology Laboratory at the Department of Genetics, Plant Physiology and Microbiology of Uzhhorod National University. Swabs from the investigated surfaces of 30 mobile phones and 30 watches were collected using disposable sterile cotton swabs moistened with sterile saline. The clinical isolates were isolated with the use of differentially diagnostic nutrient media.
Results: Studies have shown that cell phones are contaminated with pathogenic microorganisms to a much greater extent than watches. 1518 CFU were isolated from mobile phones, while 375 CFU from watches. The dominant representatives of the microflora of the studied objects were gram positive bacteria of the genus Staphylococcus. Comparative characteristics of the species composition of bacteria of the genus Staphylococcus isolated from mobile phones and watches showed that the dominant species isolated was S.epidemidis. Therefore, studies have shown a high degree of contamination of mobile phones with coagulase-positive bacteria of the genus Staphylococcus, which in most showed hemolytic properties.
Conclusions: The patterns identified indicate that mobile phones can play a role in the spread of opportunistic infection.
COMPARATIVE ANALYSIS OF CLINICAL AND LABORATORY CHARACTERISTICS OF MEASLES IN VACCINATED AND UNVACCINATED CHILDREN IN THE POLTAVA REGION (UKRAINE)
Authors: Ilchenko Valentyna I. , Syzova Liudmyla M. , Pikul Каteryna V. , Dvornyk Irynа L. , Muravlоva Oksana V.
Published: February 2022

The aim: To study the clinical and laboratory characteristics of measles, as well as to compare the course of this disease in vaccinated and unvaccinated children in the Poltava region (Ukraine).
Materials and methods: 104 inpatients with measles were examined: vaccinated (n=27) and unvaccinated (n=77). The patient examination program included: assessment of complaints and anamnestic data obtained by questioning (during admission to hospital treatment, during treatment and after discharge) and detailed analysis of medical records (Form № 003/у), physical examination, general clinical study of peripheral blood. Statistical processing of the study results was carried out by methods of variation statistics using the program «SPSS 17.0».
Results: The clinical and laboratory picture of measles in the examined patients is typical for this disease. Measles vaccinated children are significantly less likely to have fever (р=0.001) and Koplik’s spots (χ2=3.80, р=0.051), the duration of fever (р=0.001), cough (р=0.000), and the length of hospital stay (р=0.000), as well as 3.0 times less often leukopenia is detected (р=0.043) and 2.0 times less often − acceleration of ESR (р=0.023).
Conclusions: The obtained data raise the question of expanding the explanatory work on the importance of a full course of preventive vaccination among children, as well as increasing the volume of public procurement of necessary drugs to increase public access to free vaccination.
OVARY FUNCTIONAL STATE IN FEMALE ADOLESCENTS WITH A HISTORY OF INTACT UTERINE APPENDAGES TORSION
Authors: Tuchkina Iryna A. , Kiebashvili Salome V. , Guz Iryna A. , Viesich Tetiana L.
Published: February 2022

The aim: To assess the functional state of gonads in female adolescents with a history of intact uterine appendages torsion (IUAT).
Materials and methods: A total of 55 adolescent girls aged from 13 to 17 years were examined. 35 patients with a history of IUAT were divided into two groups: group 1 consisted of 21 patients with organ-preserving surgical treatment (detorsion) and group 2 of 14 patients with radical surgical treatment of IUAT. 20 healthy girls formed the control group. Assessment of the ovarian reserve was performed by the determination of serum anti-Müllerian hormone (AMH) level. Ultrasound scan was used to evaluate ovaries volume, number and diameter of antral follicles.
Results: The AMH level in control group (2.4 ± 0.29 ng/ml) has no statistically significantly differences compared with group 1 (2.2 ± 0.35 ng/ml, p = 0.12) and differed significantly compared with group 2 (0.96 ± 0.11 ng/ml, p < 0.05). No statistically significant differences in ovary volume were found between group 1 and control group (6.02 ± 0.21 cm3 and 6.14 ± 0.17 cm3, respectively, p = 0.125). The number and diameter of antral follicles in group 1 didn`t significantly differ from the control group (3.85 ± 0.35 and 4.00 ± 0.25, p = 0.116, 3.57 ± 0.42 mm and 3.70 ± 0.31 mm, p = 0.128, respectively).
Conclusions: The method of choice for IUAT treatment taking into account upcoming motherhood is laparoscopy with detorsion. Dynamic ultrasound results and determination of AMH level indicate the organ-preserving tactics for surgical treatment of IUAT.
SURGICAL SITE INFECTIONS AFTER NEUROSURGICAL PROCEDURES IN UKRAINE: RESULTS OF A MULTICENTER STUDY (2018-2020)
Authors: Salmanov Aidyn G. , Shchehlov Dmytro V. , Svyrydiuk Oleh , Bortnik Ihor M. , Mamonova Maryna , Gudym Maxim S. , Pastushyn Oleksandr A.
Published: February 2022

The aim: To obtain the first estimates the incidence of surgical site infection in patients undergoing neurosurgical procedures and antimicrobial resistance of responsible pathogens, and determine their impact on inpatient mortality in Ukraine.
Materials and methods: We performed a multicenter prospective study was patient-based data of SSIs were according to CDC/NHSN methodology. This study included patients undergoing a neurosurgical procedure in 11 tertiary care hospitals from different regions of Ukraine from January 1st, 2018 to December 31st, 2020.
Results: A total of 1697 neurosurgical procedures associated with a 90-day SSI were identified (19.4% of 8741 procedures). Of these, 69.5% SSI were identified after craniotomy and 30.5% after ventricular shunt. The Meningitis or ventriculitis (20.9%) were found to be the most common underlying condition among these patients followed by Intracranial infection (18.7%), and Osteomyelitis (14.6%) congenital malformation. Over a 90-day surveillance period, 387 died (4.4%). Fifty seven percent of deaths in SSI patients were attributable to infection. Meningitis or ventriculitis and Intracranial infection were associated with a higher mortality. Craniotomy was associated with a higher mortality more frequently than did Ventricular shunt. Escherichia coli were most commonly reported, accounting for 26.3% of all organisms, followed by Staphylococcus aureus, Enterobacter spp., Pseudomonas aeruginosa, Enterococcus spp., and Klebsiella pneumoniae. Meticillin resistance was found in 33.7% of S. aureus isolates, and vancomycin resistance was found in 12.7% of enterococci.
Conclusions: The incidence of SSI and mortality after neurosurgical procedures in Ukraine is high. This is due to increase emergence of antimicrobial-resistant pathogens and risk factors in neurosurgery patients.
ANALYSIS OF MENTAL HEALTH IN PATIENTS, WHO HAVE HAD SARS COV-2 AT THE PRIMARY LEVEL OF HEALTH CARE
Authors: Matviyets Lyudmyla G. , Matiukha Larysa F.
Published: February 2022

The aim of the study was to evaluate retrospectively the mental state of patients, who have had COVID - 19 at the primary level of health care according to medical documentation.
Materials and methods: 70 outpatient charts of patients aged from 31 to 80 years who have had laboratory-confirmed SARS CoV-2 and received primary health care, were processed. Conducted: assessment for the presence and determination of the severity of depression based on the scale of PHQ 9; screening for post-traumatic stress disorder (PTSD) (Breslau et al., 1999).
Results and conclusions: patients, who have had SARS CoV-2, the moderate severity of depressive syndrome prevailed. The risk of forming of PTSD is most presented in patients who have had severe SARS CoV-2, who had inpatient treatment and combined with low quality of life (QOL) at outpatient treatment as well. The increase of anxiety was found in individuals after outpatient and inpatient treatment, and it was accompanied with low QOL. Patients with complaints about cognitive impairment prevailed after inpatient treatment, and determined their QOL as low, especially in men in 100%. Sleep disturbances were detected in 90.3% of patients with complicated course of SARS CoV-2 during inpatient treatment with low QOL. Tachycardia was detected in 61.7% of patients in group 1 and in 52.2% in group 2, that could be a symptom of increased anxiety and PTSD, but it requires differential diagnosis with cardiac pathology.
SUBSTANTIATION OF SUBSTITUTION THERAPY MEDICATION FOR DRY EYE SYNDROME TREATMENT IN PATIENTS USING CONTACT LENS VISION CORRECTION
Authors: Kryvoviaz Olena V. , Tomashevska Yuliia O. , Toziuk Olena Iu. , Kudria Viktoriia V. , Balanchuk Tetiana I.
Published: February 2022

The aim: To substantiate the selection of a substitution therapy medication for dry eye syndrome treatment in patients wearing different kinds of contact lenses.
Materials and methods: A structural analysis of the assortment of substitution therapy medications for dry eye syndrome treatment as well as a content analysis of the information given in the labelling claims of various substitution therapy medication was conducted. Than they were segmented using the criteria of whether the substitution therapy medications may be used in patients with dry eye syndrome who wear contact lenses.
Results: The labelling claims of 82.36% substitution therapy medications registered in Ukraine assortment contain information on either full or partial compatibility with contact lenses. The use of 11.76% of the assortment is impossible for patients wearing soft contact lenses, while patients wearing hard contact lenses need to wait for some period of time (15-20 min) before putting contact lenses back on.
Conclusions: The pharmaceutical market of Ukraine is characterized by a wide assortment of substitution therapy medications for dry eye syndrome treatment, which can be used in patients wearing contact lenses. Based on the data received, it has been determined that 70.59% of substitution therapy medications are compatible with contact lenses of all types and only the use of 8.82% of the substitution therapy medications assortment is contraindicated for dry eye syndrome treatment in patients wearing contact lenses.
APPROACHES OF MEDICAL AND PHARMACEUTICAL SPECIALISTS TO INJECTION PHARMACOTHERAPY: QUESTIONNAIRE SURVEY
Authors: Ryvak Tetiana , Denysiuk Oksana , Zimenkovsky Andriy
Published: February 2022

The aim: To study medical and pharmaceutical specialists’ approaches to outpatient injection treatment and their impact on the quality of medical care.
Materials and methods: The object of the study was the answers of health care professionals (n=1408) to the questions on the use of injectable pharmacotherapy in personal treatment, listed in a specially designed questionnaire on a single protocol. System analysis, questionnaire survey, statistical, comparative-and-analytical methods were used.
Results: The quality of outpatient injectable pharmacotherapy, according to the results of a survey of medical and pharmaceutical specialist, can be considered inappropriate, as in 52.9% of respondents the local adverse reaction were significantly more likely to develop compared to the respondents who did not have any local adverse reaction (χ2=21.7819, p<0.05). Most often, the following complications of injectable pharmacotherapy occurred in the analyzed respondents: pain – 45.8%; hardening – 28.3% and reddening – 21.7%. When conducting home-based treatment, 42.8% of the respondents involved persons without medical education for the execution of procedures, which is significantly more frequent (χ2=26.5556, p<0.05) in comparison with the respondents who invited medical personnel (27.0%) and used the method of self-injection (30.2%).
Conclusions: The results of a survey of medical and pharmaceutical specialists revealed that home-based injectable treatment, based mainly on their own experience, is common in the occupational environment of health care professionals.
ULTRASOUND CHARACTERISTIC OF EMBRYO, FETAL EGG AND CHORIONIC STRUCTURES IN PREGNANT WOMEN WITH MISCARRIAGE
Authors: Lisova Kateryna M. , Kalinovska Iryna , Tokar Petro
Published: February 2022

The aim: The aim of the study was to assess the peculiarities of the formation and development of the fetoplacental system, to study the structures of the embryo, gestational sac, chorion in pregnant women with miscarriage.
Materials and methods: A comprehensive ultrasound examination of 50 pregnant women was carried out in the period from 5 to 16 weeks of pregnancy, of which 25 - with a history of miscarriage (main group), and 25 - with an unremarkable medical history (control group).
Results: We have identified the following echographic markers of adverse course and outcome of pregnancy in women with miscarriage in embryonic and early fetal periods:- lag of CRL of an embryo by 2 weeks and more at ultrasound examination in terms up to 9 weeks of gestation;- corporal or basal (near the stem of the embryo body) location of chorionic detachment with the formation of retrochorial hematoma with a volume of more than 25 ml;- pronounced progressive decrease in the volume of the gestational sac and amniotic cavity;- pronounced polyhydramnios with the presence of a coarse echopositive suspension in the amnioticcavity. The likelihood of spontaneous miscarriage and the formation of placental dysfunction is higher with the simultaneous detection of 2 or more echographic markers.
Conclusions: Ultrasound examination is necessary to assess the echographic parameters of the formation and development of the embryo and extraembryonic structures in the first trimester with a history of miscarriage in order to the subsequent choice of rational tactics of pregnancy management.
INDICATORS OF THE CELL-MEDIATED IMMUNITY IN SURGICAL PATIENTS WITH GASTRODUODENAL ULCERS COMPLICATED BY BLEEDING
Authors: Trofimov Mykola , Kryshen Valerii , Dytyatkovska Yevgeniya , Barannik Sergiy , Kravets Olha , Chukhriienko Alla , Kosynskyi Oleksandr
Published: February 2022

The aim: To determine the peculiarities of indicators dynamic of cellular level of immunity in patients with gastroduodenal ulcer complicated by bleeding and microbial contamination the periulcerous area.
Materials and methods: 80 patients with gastroduodenal ulcers complicated by bleeding were studied. Among patients in the main group, 18 (22.5%) cases were patients with bleeding gastric ulcer, 56 (70%) patients with bleeding ulcer of duodenum. The study of cellular immunity are B - CD19, Natural killers(NK) - CD16, T-helpers - CD4, T-regulatory - CD8.
Results: An active bleeding according to the Forrest classification in patients with gastric ulcer 81.7% and in patients with ulcer of the duodenum 88.3%. Depending on the endoscopic hemostasis, there was a marked decrease in T-lymphocyte indices with CD4 growth to the reference rates in cases of active bleeding (from 13±2.4% to 26.4±1.2% p<0.05) and in hemostasis with high recurrence rate from 20.8±2.3% to 31.3±2.9% and from 22.6±1.3% to 39.8±2.9% p<0.05, respectively.
Conclusions: The study found a decrease in CD16 from 3.6±1.1% to 2.6±1.1% (p<0.05) and an increase in the level of CD4, CD8, CD19 to 37.4±1.1%, 4.4±1.1% (p<0.05) and 30.8±1.2% (p<0.05), respectively, indicating that there is a decrease in the immune response in patients with gastroduodenal bleeding of ulcerative genesis.
In patients with microbial contamination of the periulcerous area by Streptococcus β-haemoliticus (107 CFU) and Klebsiella pneumoniae (106 CFU), gastric ulcers decreased the level of CD8 population from 7.3±2.1% to 7.3±2.1% to 6.4±7% (p<0.05) and from 5.8±2.8% to 4.1±2.3% (p<0.05), respectively, which may create favorable conditions for the development of recurrent bleeding.
POSTPARTUM RENAL THROMBOTIC MICROANGIOPATHY: A TURN-BASED DIFFERENTIAL DIAGNOSIS
Authors: Markin Leonid , Shatylovych Kateryna
Published: February 2022

Pregnancy-associated renal thrombotic microangiopathy is a rare condition with poor maternal outcome. Pregnancy may trigger atypical hemolytic uremic syndrome or thrombotic thrombocytopenic purpura. The article describes the clinical case of a 37-year-old woman who developed acute renal failure following complicated delivery. A turn-based differential diagnosis of atypical hemolytic uremic syndrome was performed. Unwarranted discontinuation of the targeted therapy with Eculisumab led to the development of chronic renal failure.
Pregnancy-associated atypical hemolytic uremic syndrome is a life-threatening condition rarely seen in pregnancy making its early recognition difficult. As thrombotic microangiopathies require urgent treatment, plasmapheresis should be started as soon as they are suspected, followed by Eculisumab after the confirmation of the diagnosis of atypical hemolytic uremic syndrome. This may contribute to reducing maternal morbidity and mortality rates.
The Affecting of Farmer Ages, Level of Education and Farm Experience of the farming knowledge about Kartu Tani beneficial and method of use in Parakan Distric, Temanggung Regency
Authors: Gusti Irganov Maghfiroh , Gayatri Siwi , Prasetyo Agus Subhan
Published: February 2022

This research aimed to analyze the affect of farmer ages, levels of education and farming experience of thw level of farmer knowledge about Kartu Tani beneficial and method of use in Parakan Distric, Temanggung Regency. Population of this study is farmer who joined Farmer Group and had a Kartu Tani.Respondent of this study are 60 farmer that divided by 2 village. Location of this study in Dangkel Village and Glapansari Village, Parakan Distric, Temanggung Regency. Research carried out in July 2021. The research method is survey. Method of collected data this study with interview, observe, documentary and literature. The type of data in this study is primary data and secondary data. Independent variable that using in this study is farmer ages variable, levels of education variable and farming experience variable. Dependent variable in this study is the knowledge of farmer abaout kartu tani beneficial and method of use. Method of analyze data using quantitave descriptive analyze. The result of this research that farmer ages, level of education and farming experience together affected to the level of farmer knowledge about Kartu tani beneficial and method of use. Partially ages, level of education and farming experience have positive and significant affect to the level of farmer knowledge about Kartu tani beneficial and method of use.

Penelitian ini bertujuan untuk mengetahui pengaruh umur, tingkat pendidikan dan lama pengalaman bertani terhadap tingkat penerimaan petani tentang manfaat dan cara penggunaan kartu tani. Penelitian ini dilakukan di Kecamatan Parakan, Kabupaten Temanggung. Populasi dari penelitian ini adalah petani yang masuk dalam anggota Kelompok Tani yang mendapatkan Program Kartu Tani. Sampel diambil sebanyak 60 responden yang terbagi dari dua wilayah desa. Lokasi penelitian ini adalah petani di Desa Glapansari dan Desa Dangkel, Kecamatan Parakan. Pengumpulan data dimulai dari bulan Juni 2021. Metode penelitian yang digunakan dalam penelitian ini adalah survey. Metode pengambilan data penelitian dengan wawancara, observasi, dokumentasi, dan studi pustaka. Jenis data yang dikumpulkan terdiri dari data primer dan data sekunder. Variabel bebas yang digunakan yaitu variabel umur (X1), tingkat pendidikan (X2), lama bertani (X3). Variabel Pengetahuan Petani tentang manfaat dan cara penggunaan kartu tani (Y) sebagai variabel terikat atau variabel dependent. Metode analisis data yang digunakan adalah metode analisis deskriptif kuantitatif. Hasil penelitian diketahui bahwa umur, tingkat pendidikan, dan lama bertani berpengaruh terhadap tingkat pengetahuan petani secara simultan mengenai manfaat dan cara penggunaan kartu tani. Secara parsial umur, tingkat pendidikan dan lama bertani memiliki pengaruh positif dan siginifikan terhadap tingkat pengetahuan petani mengenai manfaat dan cara penggunaan kartu tani di Kecamatan Parakan, Kabupaten Temanggung.
Influence estimation of recreation pressure on the forest trail "Buchyna" NNP "Skolivski Beskydy"
Authors: Orlov Oleg , Ragulina Marina , Lenevych O.
Published: February 2022

Complex studies of the impact of recreational pressure on the forest trail "Buchina" of NNP "Skolivski Beskydy" were carried out. It was found that the air microclimatic parameters across the all transects were shown to fluctuate. The air temperature was stable, as well as the humidity changed very slightly. The wind force gradually decreased from the middle of the forest trail to the margins. The difference in the illumination of the soil surface on the trail and adjacent areas is the most noticeable. The impact of recreational activities on the microclimatic parameters of soils is more significant than this in the air. The temperature and humidity of the soil was decreased and the density of the structure was increased towards the center of the trail. Changes in water-physical parameters of soils let us identify the initial stages of digression in the studied recreational-pressed forest ecosystems. Brioindication studies have shown that the forest area on both sides of the route, which does not experience recreational pressure, is characterized by extremely weak development of moss cover. It was represented by 5 species of mosses such as Atrichum undulatum, Polytrichum formosum, Plagiomnium undulatum, Eurhynchium angustirete and E. striatum. Those species were represented by toll turf, dendroides and rough carpet growth forms. Species diversity at the trail edges were doubled. There were founded 10 spesies of bryobionta: A. undulatum, P. formosum, Plagiomnium cuspidatum, P. ellipticum, P. undulatum, E. angustirete, Pseudoscleropodium purum, Thuidium delicatulum, T. tamariscinum, Calliergonella cuspidatа, were represented by toll turf, dendroides, rough mats and weft growth forms. In the zone of intensive trampling on the forest trail, the moss cover was completely absent. Bryophytes, which were recorded in trail margins, marked the initial stages of recreational digression (I-II) and were belonging to the group of sensitive forest species. The strongest pressure was recorded on the central part of the forest trail. However, the density of the soil structure, even in this area, didn't overtop the indicator rate for the category of "very loose soils". Our study suggests that the organization of recreational activities for the planning of permanent tourist routes (so-called "ecological trails'') in the areas of spruce-beech forests haven't cause extremely pressure on the park ecosystems (equally for soil and vegetation cover) in NNP "Skolivski Beskydy". As a preventive measure, we recommend regulating the number of visitors to reduce the mechanical trampling on the forest trails and the arrangement of different fences, decks, etc.
History of the penetration of anthropochorous mollusc species to western Ukraine
Authors: Gural-Sverlova Nina , Gural Roman
Published: February 2022

Analysis of literary sources and materials of the malacological collection of the State Museum of Natural History of the National Academy of Sciences of Ukraine in Lviv revealed that at the end of the 19th century in western Ukraine could be present only some anthropochorous species of slugs, especially Limax maximus. Instead, mentions of a number of species not belonging to the indigenous malacofauna of Ukraine and its western region, made from the second half of the 19th to the middle of the 20th century, could most likely be based on the erroneous identification of other, native species. The process of intensive penetration into western Ukraine of alien species of land molluscs began, apparently, not earlier than the middle – second half of the 20th century and significantly accelerated at the turn of the 20th and 21st centuries. The latter could be due to both climate change, which facilitated adaptation to local climatic conditions for more thermophilic species, and the active import of seedlings of ornamental plants from other European countries. In particular, a dangerous pest from the complex Arion lusitanicus s.l. could enter the territory of Ukraine in this way. No less indicative are the relatively young colonies of Cepaea nemoralis, which are increasingly found in western Ukraine. Since the end of the 20th century, species of Caucasian origin and those that were previously observed only for the southern part of the country are increasingly registered in western Ukraine. Compared to the great taxonomic diversity of land anthropochorous molluscs and the widespread distribution of some of them, a relatively small number of freshwater species (up to 8), alien to this area, are still known in western Ukraine. For most of them, only a few finds are still known, made in the early 21st century. The exception is only one species (Physella acuta), which began to be mentioned for various areas in western Ukraine in the second half of the 20th century. Among the alien freshwater molluscs are a group of small species imported to Europe from other continents: New Zealand Potamopyrgus antipodarum, North American Menetus dilatatus, Physella heterostropha and possibly also Physa skinneri and Physella acuta. Representatives of the Dreissena genus came here from the Black Sea territories in the south of Ukraine.
Сharacteristics of visible autumn migrations of the common crane Grus grus (Linnaeus, 1758) in NNP "Prypiat-Stokhid" in 2012-2017
Authors: Khymyn M.
Published: February 2022

The vіsіble mіgratіons of bіrds were study of the terrіtory of national nature park at left bank of the Prypіat Rіver near Svalovychі vіllage іn Kamin-Kashyrsk dіstrіct, Volyn regіon of Ukraіne іn September and October 2012-2017. There were 2737 individuals of the Common Crane counted at the one observation point during this time. Almost all birds migrated in flocks. Several lone birds were observed also, apparently lagging behind their flocks. There are from 2 to 222 individuals in one flock, on average – 39,0±5,12 (n=70). The main passage lasted from the 3rd decade of September to the middle of the 2nd Decade of October. The majority of them flew in the 5 last hours of observations (77,9% of all counted birds during 6 years). Most birds of this species were observed on passage at altitudes above 250 m (61,2%), less – between 100 and 250 m (36,1%), and the predominant directions of their migration were SW (48,5%) and S (40,7%).