bluuebunny/crossref_metadata_2025 huggingface dataset:
Measurement and Prediction of Coupling Coordination Level of Economic Development, Social Stability and Ecological Environment in Qinghai—Thoughts on Sustainable Societal Safety
Authors: Ye Shuai , Ge Yuejing , Xu Shiyu , Ma Xiaofan
Published: August 2022

Societal safety is the result of the coordinated development of several subsystems; the coupling–coordination relationship among economic development (ED), social stability (SS), and ecological environment (EE) is the premise of realizing sustainable societal safety (SSS). Taking Qinghai Province as an example, this paper quantitatively evaluates the development index of each subsystem by constructing ED-SS-EE evaluation index system, then analyzes the spatio-temporal evolution of ED, SS, and EE coupling coordination levels based on the coupling coordination model, and finally predicts the coupling coordination level of ED, SS, and EE by using the GM(1.1) model. The findings are as follows: (1) The economy is developing rapidly, but the regional development is extremely uneven; ED is driving SS, and SS lags behind ED and slowly improves; EE is improving continuously, and the spatial pattern is relatively stable. (2) The ED, SS, and EE systems have a high degree of coupling, showing a fluctuating upward trend. Coordination level is low, showing a slow upward trend, and the regional differences are obvious. (3) In the future, the coordination level of ED, SS, and EE systems in different regions will be upgraded from the level of near imbalance and barely coordination to the level of intermediate coordination, good coordination, and even high-quality coordination. The spatio-temporal description of ED, SS, and EE coupling coordination level not only reveals the development trend and problems of SSS in Qinghai, it also proves the feasibility of evaluating societal safety level based on the coupling coordination level of sustainable social structure system.
To Use or Not to Use: It Is a Question—An Empirical Study on the Adoption of Mobile Finance
Authors: Li Gaoyong , Zhang Xin , Zhang Ge
Published: August 2022

Due to its important impact on sustainable development, mobile finance spreads fast. However, what factors and how these factors impact the adoption of mobile finance apps are still unknown. This research employs UTAUT and research on mobile banking and payment to explore the adoption of mobile finance apps. A total of 348 questionnaires were collected online and offline and analyzed by SEM. The results show that performance expectancy, effort expectancy, social influence, facilitating conditions, trust, and perceived risk affect the intention to use mobile finance. This study makes theoretical contributions by contextualizing UTAUT and considering the indigenized factors in China and offers practical implications for mobile finance operators.
Crossed Congenital Hemihyperplasia: A Case Report
Authors: Kim Woo-Jong , Kim Byungsung , Nho Jae-Hwi , Kim Junbum , Hong Chang-Hwa , Kwon Sai-Won , Choi Young , Kim Tae-Gyun , Lee Changeui , Jung Ki-Jin
Published: August 2022

Overgrowth syndromes generally present with inherent health concerns and, in some instances, an increased risk of malignant intra-abdominal tumors, such as Wilms tumor or hepatoblastoma. There are various types of hyperplasia, but the crossed type is reported to be the rarest. We present a rare, crossed type of congenital hemihyperplasia. A six-year-old girl was referred to our clinic for leg length discrepancy and was diagnosed with congenital hemihyperplasia of the right lower limb and left upper limb. The leg length discrepancy had begun to affect the patient’s gait and stair climbing. We regularly monitored her leg length and checked for functional and cosmetic problems for 24 months. However, the hyperplasia progressed and caused severe gait impairment. Leg length discrepancy at the last check-up was 30 mm. She underwent femoral lengthening surgery using a monolateral external fixator. At the 14th month follow-up, her gait and stair climbing had greatly improved, and a scanogram revealed that the leg length discrepancy had been successfully treated with a mild varus angulation of the femur. We present a rare, crossed congenital hemihyperplasia. We recommend limb lengthening surgery for treating patients with idiopathic hemihyperplasia.
Catalytic Asymmetric Synthesis of C-Chiral Phosphonates
Authors: Kolodiazhna Anastasy O. , Kolodiazhnyi Oleg I.
Published: August 2022

The current review is devoted to the achievements in the development of methods for the catalytic asymmetric synthesis of phosphonates containing a chiral center in the side chain. C-chiral phosphonates are widely represented among natural compounds with various biological activities as insecticides, herbicides, antibiotics, and bioregulators. Synthetic representatives of this class have found practical application as biologically active compounds. The review summarizes methods of asymmetric metal complex catalysis and organocatalysis as applied to such reactions as phospha-aldol reaction, two-component and three-component phospha-Mannich reaction, phospha-Michael reaction, as well as hydrogenation of unsaturated phosphonates and phosphine oxides, ketophosphonates, and iminophosphonates. Methods for the asymmetric hydride reduction of C=X phosphonates (X=O, S, NR) are also discussed in detail. The review presents updated literature reports, as well as original research by the author.
Chinese VFR Travel in Budapest: The Hosts’ Roles
Authors: Song-Agócs Rita , Michalkó Gábor
Published: August 2022

In recent decades, there has been a dynamic growth of Chinese outbound tourism to the Central and Eastern European region, and Hungary has been one of the most visited countries. This increase in demand is linked, in part, to the important Chinese diaspora in Hungary whose members play the role of hosts in VFR travel. This paper aims to explore the social relations—guanxi—within the Chinese diaspora living in Budapest and its influence on VFR travels back and forth China. Results of the survey with 202 Chinese immigrants reveal the strong nexus between migration and VFR travel. The Chinese hosts who have been living in the country for two decades behave differently in their guanxi compared to those who have settled in Budapest recently. The article provides several practical contributions to local destination management organizations and tourism service providers to successfully reach Chinese hosts, such as providing commissions, coupons, and getting discounts.
From Immunotoxins to Suicide Toxin Delivery Approaches: Is There a Clinical Opportunity?
Authors: Ardini Matteo , Vago Riccardo , Fabbrini Maria Serena , Ippoliti Rodolfo
Published: August 2022

Suicide gene therapy is a relatively novel form of cancer therapy in which a gene coding for enzymes or protein toxins is delivered through targeting systems such as vesicles, nanoparticles, peptide or lipidic co-adjuvants. The use of toxin genes is particularly interesting since their catalytic activity can induce cell death, damaging in most cases the translation machinery (ribosomes or protein factors involved in protein synthesis) of quiescent or proliferating cells. Thus, toxin gene delivery appears to be a promising tool in fighting cancer. In this review we will give an overview, describing some of the bacterial and plant enzymes studied so far for their delivery and controlled expression in tumor models.
Primary Cutaneous Cryptococcosis Caused by Cryptococcus gatti in an Elderly Patient
Authors: Belda Walter , Casolato Ana T. S. , Luppi Juliana B. , Passero Luiz Felipe D. , Criado Paulo R.
Published: August 2022

According to the spread of Cryptococcus sp., fungal infections can be classified as primary or secondary. In primary cutaneous cryptococcosis, the fungi are restricted to the skin of the patients, without systemic involvement. The incidence of primary cutaneous cryptococcosis is high in patients with immunosuppression, and this type of infection is rarely observed in patients who are immunocompetent. In the present case report, a patient who is immunocompetent and has systemic comorbidity reported that, after skin trauma, ulcerovegetative lesions appeared in the right upper arm; the etiologic agent was identified as Cryptococcus gatti, serotype B. The cutaneous lesions healed completely after 5 months of fluconazole treatment.
Varidnaviruses in the Human Gut: A Major Expansion of the Order Vinavirales
Authors: Yutin Natalya , Rayko Mike , Antipov Dmitry , Mutz Pascal , Wolf Yuri I. , Krupovic Mart , Koonin Eugene V.
Published: August 2022

Bacteriophages play key roles in the dynamics of the human microbiome. By far the most abundant components of the human gut virome are tailed bacteriophages of the realm Duplodnaviria, in particular, crAss-like phages. However, apart from duplodnaviruses, the gut virome has not been dissected in detail. Here we report a comprehensive census of a minor component of the gut virome, the tailless bacteriophages of the realm Varidnaviria. Tailless phages are primarily represented in the gut by prophages, that are mostly integrated in genomes of Alphaproteobacteria and Verrucomicrobia and belong to the order Vinavirales, which currently consists of the families Corticoviridae and Autolykiviridae. Phylogenetic analysis of the major capsid proteins (MCP) suggests that at least three new families should be established within Vinavirales to accommodate the diversity of prophages from the human gut virome. Previously, only the MCP and packaging ATPase genes were reported as conserved core genes of Vinavirales. Here we report an extended core set of 12 proteins, including MCP, packaging ATPase, and previously undetected lysis enzymes, that are shared by most of these viruses. We further demonstrate that replication system components are frequently replaced in the genomes of Vinavirales, suggestive of selective pressure for escape from yet unknown host defenses or avoidance of incompatibility with coinfecting related viruses. The results of this analysis show that, in a sharp contrast to marine viromes, varidnaviruses are a minor component of the human gut virome. Moreover, they are primarily represented by prophages, as indicated by the analysis of the flanking genes, suggesting that there are few, if any, lytic varidnavirus infections in the gut at any given time. These findings complement the existing knowledge of the human gut virome by exploring a group of viruses that has been virtually overlooked in previous work.
Detection of Apparent Early Rabies Infection by LN34 Pan-Lyssavirus Real-Time RT-PCR Assay in Pennsylvania
Authors: Dettinger Lisa , Gigante Crystal M. , Sellard Maria , Seiders Melanie , Patel Puja , Orciari Lillian A. , Yager Pamela , Lute James , Regec Annette , Li Yu , Xia Dongxiang
Published: August 2022

The Pennsylvania Department of Health Bureau of Laboratories (PABOL) tested 6855 animal samples for rabies using both the direct fluorescent antibody test (DFA) and LN34 pan-lyssavirus reverse transcriptase quantitative PCR (RT-qPCR) during 2017–2019. Only two samples (0.03%) were initially DFA negative but positive by LN34 RT-qPCR. Both cases were confirmed positive upon re-testing at PABOL and confirmatory testing at the Centers for Disease Control and Prevention by LN34 RT-qPCR and DFA. Rabies virus sequences from one sample were distinct from all positive samples processed at PABOL within two weeks, ruling out cross-contamination. Levels of rabies virus antigen and RNA were low in all brain structures tested, but were higher in brain stem and rostral spinal cord than in cerebellum, hippocampus or cortex. Taken together, the low level of rabies virus combined with higher abundance in more caudal brain structures suggest early infection. These cases highlight the increased sensitivity and ease of interpretation of LN34 RT-qPCR for low positive cases.
Healthcare-Associated SARS-CoV-2 Reinfection after 3 Months with a Phylogenetically Distinct Omicron Variant: A Case Report
Authors: Callebaut Kim , Stoefs Anke , Stylemans Dimitri , Soetens Oriane , Crombé Florence , Vancutsem Ellen , Imamura Hideo , Wybo Ingrid , De Geyter Deborah , Piérard Denis , Muyldermans Astrid , Demuyser Thomas
Published: August 2022

This case report describes a 60-year-old female patient suffering from systemic sclerosis, for which she received immunomodulatory drugs. Her first SARS-CoV-2-positive nasopharyngeal sample was obtained in the emergency department, on 31 January 2022. Whole genome sequencing confirmed infection with Omicron BA.1.1. Her hospital stay was long and punctuated by many complications, including admission to the intensive care unit. At the beginning of April 2022, she started complaining of increased coughing, for which another SARS-CoV-2 RT-qPCR test was performed. The latter nasopharyngeal swab showed a strongly positive result. To support the theory of healthcare-associated reinfection, whole genome sequencing was performed and confirmed reinfection with Omicron BA.2. Since this patient was one of ten positive cases in this particular ward, a hospital outbreak investigation was performed. Whole genome sequencing data were available for five of these ten patients and showed a cluster of four patients with ≤2 small nucleotide polymorphisms difference.
Emerging Genotype IV Japanese Encephalitis Virus Outbreak in New South Wales, Australia
Authors: Howard-Jones Annaleise R. , Pham David , Jeoffreys Neisha , Eden John-Sebastian , Hueston Linda , Kesson Alison M. , Nagendra Vanathi , Samarasekara Harsha , Newton Peter , Chen Sharon C.-A. , O’Sullivan Matthew V. , Maddocks Susan , Dwyer Dominic E. , Kok Jen
Published: August 2022

The detection of a new and unexpected Japanese encephalitis virus (JEV) outbreak in March 2022 in Australia, where JEV is not endemic, demanded the rapid development of a robust diagnostic framework to facilitate the testing of suspected patients across the state of New South Wales (NSW). This nascent but comprehensive JEV diagnostic service encompassed serological, molecular and metagenomics testing within a centralised reference laboratory. Over the first three months of the outbreak (4 March 2022 to 31 May 2022), 1,061 prospective samples were received from 878 NSW residents for JEV testing. Twelve confirmed cases of Japanese encephalitis (JE) were identified, including ten cases diagnosed by serology alone, one case by metagenomic next generation sequencing and real-time polymerase chain reaction (RT-PCR) of brain tissue and serology, and one case by RT-PCR of cerebrospinal fluid, providing an incidence of JE over this period of 0.15/100,000 persons in NSW. As encephalitis manifests in <1% of cases of JEV infection, the population-wide prevalence of JEV infection is likely to be substantially higher. Close collaboration with referring laboratories and clinicians was pivotal to establishing successful JEV case ascertainment for this new outbreak. Sustained and coordinated animal, human and environmental surveillance within a OneHealth framework is critical to monitor the evolution of the current outbreak, understand its origins and optimise preparedness for future JEV and arbovirus outbreaks.
A Novel Single-Stranded RNA-Based Adjuvant Improves the Immunogenicity of the SARS-CoV-2 Recombinant Protein Vaccine
Authors: Liu Dong , An Chaoqiang , Bai Yu , Li Kelei , Liu Jianyang , Wang Qian , He Qian , Song Ziyang , Zhang Jialu , Song Lifang , Cui Bopei , Mao Qunying , Jiang Wei , Liang Zhenglun
Published: August 2022

The research and development (R&D) of novel adjuvants is an effective measure for improving the immunogenicity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recombinant protein vaccine. Toward this end, we designed a novel single-stranded RNA-based adjuvant, L2, from the SARS-CoV-2 prototype genome. L2 could initiate retinoic acid-inducible gene-I signaling pathways to effectively activate the innate immunity. ZF2001, an aluminum hydroxide (Al) adjuvanted SARS-CoV-2 recombinant receptor binding domain (RBD) subunit vaccine with emergency use authorization in China, was used for comparison. L2, with adjuvant compatibility with RBD, elevated the antibody response to a level more than that achieved with Al, CpG 7909, or poly(I:C) as adjuvants in mice. L2 plus Al with composite adjuvant compatibility with RBD markedly improved the immunogenicity of ZF2001; in particular, neutralizing antibody titers increased by about 44-fold for Omicron, and the combination also induced higher levels of antibodies than CpG 7909/poly(I:C) plus Al in mice. Moreover, L2 and L2 plus Al effectively improved the Th1 immune response, rather than the Th2 immune response. Taken together, L2, used as an adjuvant, enhanced the immune response of the SARS-CoV-2 recombinant RBD protein vaccine in mice. These findings should provide a basis for the R&D of novel RNA-based adjuvants.
Administration of Vaccines in Dairy Sheep and Goat Farms: Patterns of Vaccination, Associations with Health and Production Parameters, Predictors
Authors: Lianou Daphne T. , Michael Charalambia K. , Petinaki Efthymia , Mavrogianni Vasia S. , Fthenakis George C.
Published: August 2022

This paper reports findings regarding patterns of vaccine usage in sheep and goat farms, in 325 sheep flocks and 119 goat herds throughout Greece. The objectives of the study were (a) to describe the patterns of vaccine administration in small ruminant farms and (b) to highlight factors that were associated with vaccinations in the farms. Vaccination against brucellosis was performed in all farms into the study. Among optional vaccinations, anti-clostridial vaccination was most frequently performed (in 97.8% of farms), followed by vaccination against contagious agalactia, (56.5% of farms), pneumonia (41.2%), chlamydial abortion (38.1%), staphylococcal mastitis (36.0%), and paratuberculosis (9.5%). Vaccinations against pneumonia and staphylococcal mastitis were performed more frequently in sheep flocks, whilst vaccinations against paratuberculosis were performed more frequently in goat herds. On average, 2.8 and 2.7 optional vaccinations (i.e., additionally to vaccination against brucellosis) were performed in sheep and goat farms, respectively. The increased number of vaccines administered was associated with a higher average milk production in the respective farms. There was an association of vaccination against staphylococcal mastitis with a reduced recovery of staphylococci from the bulk-tank raw milk. In multivariable analyses, significant associations of the administration of the various optional vaccines were seen with 15 variables, 11 related to health management practices and 4 related to the demographic characteristics of farmers; the collaboration with a veterinarian, the daily number of milking sessions, and the period spent daily by the farmer at the farm premises were each associated with the administration of vaccines against three infections.
Development of toxic shock syndrome as one of the causes of mortality in streptococcal infection
Authors:   City Hospital No. 5, Krasnoyarsk, Petrishcheva O. A.
Published: August 2022

Toxic shock syndrome is a condition in which a state of shock with a drop in blood pressure to critical numbers and multiple organ failure develops against the background of exposure to endoand exotoxins produced by bacteria and viruses. Every third patient who enters the intensive care unit suffers from certain manifestations of toxic shock syndrome. This term was first introduced in 1978 by the English pediatrician Jim Todd, who observed hyperthermia, hypotension, occurrence of rashes against the background of confusion and severe asthenia in patients. Type B enterotoxin produced by Staphylococcus aureus was isolated from blood samples of one of the patients, which made it possible to suspect the infectious nature of this process. This pathological condition can be observed with the development of postpartum sepsis, presence of wounds and burn surfaces, including closed wounds, occur against the background of postoperative interventions, or complicate the course of allergic contact dermatitis. Mortality in toxic shock syndrome reaches 5-15%, and if Streptococcus pyogenes acts as the causative agent, the mortality rate can increase several times and reach 50-60%. The main reservoir of streptococcus in the human body is the pharynx, but at the same time it can be found on the surface of the skin, rectal mucosa and vagina. A considerable number of cases of the development of toxic shock syndrome occurs in women who have been using vaginal tampons during menstruation for a long time.
Efecto de una pasta dental con xilitol sobre Streptcococcos mutans en pacientes con ortodoncia fija
Authors: Padilla-Cáceres Tania Carola , Centeno-San Román Gilberto , Catacora-Padilla Paula Olenska , Acero-Condori Lizbeth , Mamani-Cori Vilma , Cervantes-Alagón Sheyla Lenna , Sucari Wilson
Published: August 2022

La terapia ortodóntica produce una mayor acumulación de placa bacteriana en los pacientes, observándose cambios ecológicos orales que causan aumento del número de estreptococos mutans, por lo que es importante una adecuada higiene bucal que ayude a disminuir las bacterias y prevenir la caries. Objetivo. El propósito fue comparar el efecto del uso de una pasta dental con xilitol, en el recuento de Streptcococcos mutans en pacientes con aparatología ortodóntica fija. Material y métodos. Se realizó un estudio cuasiexperimental de cegamiento simple. La muestra estuvo constituida por 34 pacientes adolescentes con aparatología ortodontica fija de ambo sexos que cumplieron los criterios establecidos, todos fueron instruidos en una técnica de cepillado y designados al azar a uno de los dos grupos: grupo experimental 17 pacientes que usaron una pasta dental con xilitol y 17 pacientes en el grupo control que utilizaron una pasta dental convencional con flúor. A ambos grupos se les tomó y procesó microbiológicamente placa bacteriana al inicio del estudio y a las 3 y 5 semanas para evaluar el recuento de streptococos mutans. Resultados. La prueba T-Student demostró que hubo menos unidades formadoras de colonias en los pacientes que utilizaron pasta dental con xilitol siendo significativa la diferencia en la quinta semana de uso (? 0.0001). Conclusiones. Existe mayor efectividad de la pasta dental con xilitol, en relación a la pasta dental solo con flúor en el recuento de Streptococos mutans, sin embargo, los pacientes de ambos grupos tuvieron menos unidades formadoras de colonias.
Regional Original Revenue, Regional Expenditure, Economic Growth and Human Development Index (City/Regency Government in North Sumatra Province)
Authors: Siregar Oktarini Khamilah
Published: August 2022

The Human Development Index is an indicator of the success of local governments in improving the welfare of their people. The HDI in the city/district government of North Sumatra Province is only the Medan City government which has a very high category of 80 percent based on the UNDP assessment. The study wanted to test Regional Original Income, Regional Expenditures and Economic Growth the effect on HDI in City and Regency Governments in North Sumatra using a research method with a causal associative approach. The research sample uses panel data from 32 City and Regency Governments during 2019 to 2020. The results show that Regional Original Income and Economic Growth have not been able to increase HDI, while Regional Expenditures can increase HDI in City and Regency Governments in North Sumatra. However, regional spending has not been fully utilized properly in increasing the HDI. It is necessary to increase regional original income by opening up investment in the region and by stimulating regional original income and increasing economic growth so that the quality of human resources increases.
Pengaruh Iklim Organisasi dan Kepuasan Kerja terhadap Kinerja Karyawan pada PT. Astra Motor Internasional
Authors: Tampubolon Rhoni Ilham
Published: August 2022

The research objective to be achieved by the authors of this study is to determine whether organizational climate has a positive and significant effect on employee performance at PT. Astra Motor Internasional, does Job Satisfaction have a positive effect on employee performance at PT. Astra Motor Internasional, and whether the Organizational Climate and Job Satisfaction have a positive and significant effect on the performance of employees at PT. Astra Motor International. The population and sample in this study were employees of PT. Astra Motor International, amounting to 104 employees. The data analysis techniques used were Technical Data Analysis, Data Analysis Test, Multiple Linear Regression Analysis Test, Classical Assumption Test and Hypothesis Test, namely t test (partial), f test (simultaneous) and the coefficient of determination. Based on the results of the partial test (t test), it can be concluded that Organizational Climate has a significant effect on employee performance. Job Satisfaction has a significant influence on employee performance. Based on the results of the F test, it can be concluded that the variables of Organizational Climate and Job Satisfaction simultaneously have a significant effect on employee performance. The R-Square value obtained is 0.424, indicating that about 42.4% of the Y variable (Employee Performance) can be explained by the Organizational Climate variable (X1) and Job Satisfaction (X2).
Innovative Development of Renewable Energy During The Crisis Period and Its Impact on the Environment
Authors: Gavkalova Nataliia , Lola Yuliia , Prokopovych Svitlana , Akimov Oleksandr , Smalskys Vainius , Akimova Liudmyla
Published: August 2022

The article examines the innovative trends in the renewable power generation, taking into account the impact of crises, as well as the impact of renewable energy on air pollution in the world (environmental change). Hierarchical agglomerative and iterative methods of cluster analysis, as well as econometric models were used to test the hypotheses. Carbon dioxide emissions and renewable power generation for 78 countries during 2000-2020 are taken into account as the database of the study. The results showed that there are groups of countries with sharp, high, moderate and low growth rates of renewable power generation. In addition, the results of econometric analysis indicate that the growth of renewable power generation does not always cause a decrease in carbon dioxide emissions. For a number of countries (Australia, Canada, Mexico, Poland) such connection is not essential at all. The results of the study can be useful in shaping and adapting environmental strategies around the world.
Tamizaje fitoquímico y evaluación de la actividad antioxidante de extractos etanólicos de Bursera graveolens (Burseraceae).
Authors: Álvarez Lario Darío Ángel , Ibáñez Borrero Ever José , Castillo Contreras Osnaider , Márquez Vizcaíno Rita Luz
Published: August 2022

El presente trabajo se desarrolló, con el objetivo de cuantificar el contenido de fenoles y flavonoides y determinar, la actividad antioxidante en los extractos y fracciones de hojas y corteza de Bursera graveolens (Kunth) Triana y Planch.
Impacto del Uso de Vegetación dn Ambientes Urbanos: Techos y Muros Verdes
Authors: Viecco Márquez Margareth
Published: August 2022

Las actividades antropogénicas han desencadenado múltiples impactos ambientales negativos colocando en riesgo la salud humana y a su entorno....
De la Ciencia con Humanidad, de los Investigadores con Ética, Bioética y de los Anticristos
Authors: Rauchwerge Rodríguez Erick
Published: August 2022

Un INVESTIGADOR sin ÉTICA y que no tiene principios BIOÉTICOS, NO ES MAS QUE UN ANIMAL HACIENDO PSEUDOCIENCIA. La ética le plantea al investigador ¿Qué debo hacer?, mientras que la bioética le propone, ¿Qué consecuencias hay, si lo hago?
Actividad antifúngica de algunos derivados del 4-nerolidilcatecol sobre Moniliophthora roreri, agente causal de moniliasis en frutos de cacao
Authors: LADINO-VARGAS Cristobal , GARZÓN POSSE Fabián Andrés , PATIÑO LADINO Oscar Javier , PRIETO RODRÍGUEZ Juliet Angélica
Published: August 2022

Moniliophthora roreri es un hongo fitopatógeno que afecta los frutos del cultivo de cacao[1], causando pérdidas del 40 al 100% de la cosecha en cultivos susceptibles[2]. En el control de hongos fitopatógenos  se utilizan productos químicos poco selectivos[3], que inducen la aparición de cepas resistentes[4], siendo necesario buscar fuentes alternativas de control...
Caracterización química y evaluación de la actividad biológica sobre líneas celulares tumorales de extracto de hojas de Tillandsia sp
Authors: Rojas Fonseca Laura Yinneth , Fiorentino Susana , Modesti Costa Geison
Published: August 2022

El cáncer es un conjunto de enfermedades caracterizadas por el crecimiento y multiplicación incontrolada de células anormales.
Estudio de la acción insecticida de constituyentes químicos presente en aceites esenciales sobre Sitophilus zeamais.
Authors: Nagles-Galeano Leidy J , Prieto-Rodríguez Juliet A , Cuca-Suarez Luis E , Patiño-Ladino Oscar J
Published: August 2022

Sitophilus zeamais es una plaga cosmopolita, que causa pérdidas superiores al 20% en granos almacenados, principalmente en maíz.
Actividad citotóxica in vitro de extractos etanólicos de células de Thevetia peruviana cultivadas en biorreactor
Authors: JIMÉNEZ Stephanie , RÍOS Rosaly , MENDOZA Dary , ARIAS Juan Pablo , ARIAS Mario
Published: August 2022

Thevetia peruviana es una planta ornamental con alto contenido de glucósidos cardiotónicos con actividades ionotrópica, antitumoral y citotóxica.
Potencial insecticida de algunos aceites esenciales provenientes de plantas colombianas para el control de plagas de granos almacenados
Authors: MAHECHA- JIMENEZ Yudy S , SIERRA- QUITIAN Andres G , PRIETO-RODRIGUEZ Juliet A , PATIÑO-LADINO Oscar J
Published: August 2022

En el almacenamiento los cereales son afectados por insectos que generan grandes pérdidas, siendo de las más importantes los géneros Sitophilus y Tribolium.
Extractos de plantas de la región Caribe colombiana contra larvas del mosquito vector del dengue, zika y chikungunya.
Authors: Oliveros-Díaz Andrés , Cerra-Domínguez José , Pájaro-González Yina , Cabrera-Barraza Julián , Quiñones-Fletcher Winston , Díaz-Castillo Fredyc
Published: August 2022

El mosquito Aedes aegypti, es el principal vector de los virus del Dengue, Zika y Chikungunya. Debido a la inexistencia de vacunas para estas enfermedades, los insecticidas sintéticos han sido, las principales herramientas para controlar el vector y evitar la propagación de los virus.
Actividad alelopática de extractos de Astronium graveolens Jacq.
Authors: ORDUZ BARÓN Erika Yurley , RODRÍGUEZ ORTIZ Olga Lucía , CELIS CELIS Erika Mayerly , BOTERO LONDOÑO Julian Mauricio , RONDON FLOREZ Carlos
Published: August 2022

Uno de los mayores obstáculos en el manejo y productividad de los cultivos, es la presencia de arvenses.
Aislamiento de dos compuestos isoprenoides y alcohol lignocerílico a partir del extracto etanólico de las hojas de Capparis odoratissima Jacq.
Authors: Pajaro González Yina , Castro Larios Elizabeth , Oliveros Díaz Andrés , Mulett Vidal Jadys , Quiñones Flethcher Wistón , Fredyc Diaz Castillo
Published: August 2022

Capparis odoratissima Jacq. (Capparaceae) pertenece al género Capparis, dentro del cual se encuentran alrededor de 250 especies distribuidas mayoritariamente en la India, aunque pueden ser encontradas en Centro América, Venezuela y Colombia.
Composición química del aceite esencial de Piper el- bancoanum Trel & Yunck del pacífico colombiano
Authors: Pino Benítez Nayive , Stashenko Elena E.
Published: August 2022

El aceite esencial de hojas Piper el-bancoanum Trel & Yunck, recolectadas en el pacífico colombiano carece de información química conocida.
Evaluación del potencial larvicida en el extracto total en etanol y metanol del cuerpo fructífero de Chlorophyllum molybdites sobre Aedes aegypti.
Authors: Mercado Agamez Jaider José , Márquez Viscaíno Rita Luz , Estrada Reyes David José
Published: August 2022

En el presente estudio se evaluó la actividad larvicida de extractos obtenidos a partir del cuerpo fructífero de Chlorophyllum molybdites, colectados en el municipio de Galeras en el departamento de Sucre sobre larvas de III estadio de Aedes aegypti, se utilizaron extractos etanólico y metanólico a concentraciones de 10, 100, 500, 1000 y 2000 µg/mL.
Elaboración de un gel antibacterial a partir de la pulpa de sábila (Aloe vera).
Authors: García Rodriguez Sarai , Ramírez Hernández Johana , Bárcena Vicuña Guadalupe Gabriela , Reyes Jurado D Fátima
Published: August 2022

En este proyecto se propone, la elaboración de un gel antibacterial a partir de parénquima (gel) de Aloe vera, con esencia de lavanda y jazmín.
“Seccadeyi Suya Serme” Motifi ve Klasik Türk Şiirine Yansımaları
Authors: KEKLİK Murat
Published: August 2022

“Seccadeyi suya serme” motifi destan ve halk hikâyelerinde, Alevi-Bektaşi menkıbelerinde ve Dede Korkut hikâyelerinde karşılaşılan bir motiftir. Zamanla klasik Türk şiiri metinlerinde, az da olsa modern Türk şiirinde yer alan bir metafora dönüşmüştür. Motif; Sümer, Hint, Çin, Hristiyanlık gibi inanç ve kültürlerde mitolojik çağlara uzanan, Türklerin İslam öncesi inançlarına işaret eden bir anlam derinliğine sahiptir. Motifin yapısında yer alan “seccade” ve “su” kavram ve metaforlarının bağdaştırılması, inanç ve kültürlerdeki iç içe geçmişliğin ve kaynaşmışlığın, senkretizmin dildeki cisimleşmesidir. Kimi Farsça metinlerde seccâde ber-âb efkend şeklinde geçen tabirin Türkçe metinlerdeki kullanımı daha yaygındır. Menkıbelerde, tasavvufi metinlerde, din dışı şiirlerde tabire farklı anlamlar yüklenmiştir. Klasik Türk şiirinde motifin özellikle Hızır’la ilişkilendirildiği de görülmüştür. Tabirin anlam ve muhtevasına ise tarihi kaynaklarda ve sözlüklerde değinilmemiştir. Günümüz sözlüklerinden ikisinde karşılaşılan tabire verilen anlamlar ise hatalıdır. Çalışmada motifin senkretik yapısı gereği tabirin anlam çerçevesini daha iyi çizebilmek için seccade, su, Hızır kavram ve metaforları üzerinde durulmuştur. Mitolojilerdeki, menkıbelerdeki izleri araştırılarak tabirin klasik Türk şiirindeki anlam çerçevesi beyit örnekleri üzerinden çizilmeye çalışılmıştır.
Aplicação da norma regulamentadora NR-12 em bancada didática
Authors: Lara Hygor Santiago , Silva Josué Natan , Brito Jorge Nei
Published: August 2022

Mundialmente a prevenção de acidentes se tornou prioridade no meio industrial nas últimas décadas. O Brasil até pouco tempo atrás era citado por organismos internacionais como a Organização Internacional do Trabalho e a Organização das Nações Unidas como um país que não se preocupava com a saúde do trabalhador. Muitos acidentes ocorrem devido às más condições dos equipamentos e proteções ineficientes. Investimentos nesta área não é apenas uma questão humana, mas também, financeiramente importante. A partir deste quadro foi criada a Norma Regulamentadora 12 (NR12) que visa garantir a saúde e a integridade física dos trabalhadores e estabelece requisitos mínimos para a prevenção de acidentes e doenças do trabalho nas fases de projeto e utilização de máquinas e equipamentos de todos os tipos. Entretanto, mesmo com a criação da NR 12 muitos acidentes de trabalho que poderiam ser evitados ainda ocorrem. Principalmente em empresas de pequeno a médio porte onde o capital de giro não permite investimentos maiores em segurança. Devido a isto a norma é constantemente atualizada e complementada. Este trabalho buscou contribuir com a divulgação da norma mostrando a necessidade de conhecê-la e aplicá-la corretamente em todos os ambientes que possuem máquinas e equipamentos. Ele apresentou um estudo prático onde a norma foi aplicada em uma bancada didática do Laboratório de Sistemas Dinâmicos da UFSJ (LASID). Foram explicitados os perigos e riscos a qual o operador da bancada e colegas de trabalho estavam submetidos e a partir disto foram propostas as alterações para adequar a bancada a NR12 visando garantir a saúde e integridade física de todos. Para projetar os componentes utilizaram-se dois softwares de desenhos industriais, SolidWorks® e AutoCAD®. A partir deste trabalho foi possível sugerir alterações a bancada visando adequá-la a norma e garantir a segurança de seus usuários. Foi possível também evidenciar os perigos e riscos da sua não aplicação no Laboratório. Poderão se beneficiar deste estudo membros do Grupo de Estudos e Pesquisas do Laboratório de Sistemas Dinâmicos da UFSJ (Gep_LASID) e profissionais de todas as áreas envolvidos com segurança industrial.
Ocorrência de Botulismo em cão – relato de caso
Authors: Mendonça Ana Flávia , Martins Guilherme da Silva , Monteiro Brenda Barroso Augusto , Mansur Lorena Marin Costa , Zavanelli Giovana Rodrigues , Santana Iara Souza , Repetti Cláudia Sampaio Fonseca , Franco Rodrigo Prevedello
Published: August 2022

O botulismo canino possui com etiologia o Clostridium botulinum produtor das neurotoxinas botulínicas, que promove o quadro de neuroparalisia em função do bloqueio da acetilcolina na junção neuromuscular, resultando na tetraparesia flácida. O diagnóstico definitivo é firmado pela detecção da toxina no soro sanguíneo com inoculação em camundongos. Assim, o presente trabalho tem como objetivo relatar a ocorrência do botulismo em um cão. Para isso, um canino, macho, sem raça definida (SRD), três meses de idade, pesando 5,4kg chegou para atendimento clínico apresentando tetraparesia flácida com progressão de 24 horas. O seu tutor relatou que o mesmo possui hábitos de ingerir carcaças de frangos em decomposição ou excretos de frangos. Ao exame físico foi constatada os seguintes parâmetros clínicos; 38.6°C de temperatura, 144 de frequência cardíaca, 24 de frequência respiratória, dois segundos de perfusão tecidual e ausência de desidratação. Contudo, constatou-se a presença da tetraparesia flácida com ausência dos reflexos de retirada, panículo e propriocepção em membros posteriores e anteriores. Exames complementares foram realizados visando descartar lesões medulares em região cervical e toracolombar. Os exames laboratoriais demostraram eritrocitose e discreta trombocitopenia. A terapia suporte foi instituída a base de fluidoterapia intravenosa, analgesia, antibioticoterapia, fisioterapia e complexos vitamínicos diariamente, com a evolução progressiva do paciente em 10 dias com retorno de forma progressiva os reflexos dos membros e sua permanência em estação, com posterior locomoção. Assim, em função da história e evolução clínica do paciente, pode-se fechar o diagnóstico em botulismo canino por Clostridium botulinum.
A visão da população da região central de Rondônia sobre as queimadas urbanas e outras questões ambientais
Authors: Bergamasco Izabelly Vonrondov , De Paula Jania Maria
Published: August 2022

Entre os problemas ambientais enfrentados pela população do estado de Rondônia, estão as queimadas, sejam em áreas florestadas, em pastagens ou em áreas urbanas. As queimadas urbanas são práticas efetivamente ilegais e consideradas crime, contudo, são muito recorrentes, principalmente nos períodos de seca ou o chamado verão amazônico. Sua ocorrência se dá tanto pela ausência de medidas punitivas por parte de autoridades competentes, quanto pelo hábito cultural e neste caso, as práticas de queimadas urbanas são toleradas pela população local. O presente texto é o resultado da pesquisa “A visão da população da região central de Rondônia sobre as queimadas urbanas e outras questões ambientais” desenvolvida como requisito para a conclusão do curso Técnico em Florestas integrado ao Ensino Médio do Instituto Federal de Rondônia – campus Ji-Paraná. Teve por objetivo compreender qual percepção das populações residentes nos municípios rondonienses de Ji-Paraná, Ouro Preto do Oeste e Presidente Médici localizados na região central de Rondônia, em relação às queimadas urbanas. Adotou como metodologia a Pesquisa Social (GIL, 1999), com aplicação de enquetes através da plataforma do Google Forms. Os resultados obtidos são discutidos e analisados no corpo do presente texto.
A licença paternidade como meio de combate ao preconceito contra a mulher no mercado de trabalho
Authors: Rates Gustavo Lobato , Rubião André
Published: August 2022

A equiparação da licença paternidade à licença maternidade vem se tornando uma das principais pautas na luta pela igualdade de gênero e, sobretudo, na equânime repartição dos ônus envolvidos na dinâmica da gravidez. Este trabalho apresenta uma análise da atual legislação brasileira a respeito do tema, comparando-a com as normas vigentes nos Estados Unidos, Islândia e Dinamarca. Trata-se de avaliar, sob o prisma da razoabilidade socioeconômica, de que maneira melhores alternativas podem ser inseridas no contexto pátrio. A pesquisa é baseada no método dedutivo, do tipo qualitativo e teórico, com emprego de material bibliográfico diversificado, em especial as legislações estrangeiras. Verificou-se que a equiparação das licenças já mencionadas são fundamentais na luta contra a discriminação feminina no mercado de trabalho e contribuindo também para uma maior inserção do homem no contexto doméstico. Todavia, apesar de fundamental, o afastamento dos pais do ambiente laboral não pode alongar-se de forma desproporcional, como no caso da Dinamarca, em função dos riscos dos impactos indesejáveis no orçamento público. Defende-se a tese de que um bom exemplo para a legislação brasileira seria o modelo islandês, capaz de sopesar a necessidade com a razoabilidade.
Perspectivas da avaliação da aprendizagem matemática: estudo de caso sobre memorização de fórmulas na prova
Authors: Pereira André José , Costa Paulo César , Ribeiro Flávio Cantuária , Camargo Aline Chaves de , Peralta Icaro Moreira , Antunes Geancarlo Almeida , Vieira Savio Oliveira , Monção Fabrício Figueredo
Published: August 2022

Neste trabalho, apresenta-se a discursão sobre o tema bastante questionado na sala de aula: “Disponibilizar das expressões pré-estabelecidas na avaliação” que “simplificam” o processo de raciocínio na hora do cálculo e interpretação que são conhecidas como fórmulas matemáticas. O objetivo é entender quais são os pontos positivos e negativos dessa metodologia de avaliação. A pesquisa foi feita com base em questionário aplicado a professores de matemática que atuam em diferentes níveis do ensino.
Procedimento incremental-iterativo de dois passos para análise não linear de treliças com o método posicional de elementos finitos
Authors: Souza Luiz Antonio Farani de , Caetano Ana Caroline
Published: August 2022

Treliças submetidas a carregamentos de grande magnitude apresentam não linearidade geométrica e, em geral, aparecem pontos limites de força e/ou de deslocamento nas trajetórias de equilíbrio das mesmas. A estrutura quando atinge tais pontos pode tornar-se instável e, por isso, a identificação desses pontos é de grande importância na análise estrutural. Nesse contexto, um algoritmo é desenvolvido a partir de um método iterativo de dois passos e com convergência de ordem cúbica, adaptando-o num procedimento incremental para a solução do sistema de equações não lineares que descreve o problema estrutural. O Método Posicional dos Elementos Finitos é utilizado na discretização das estruturas. Esse método é considerado uma abordagem alternativa para problemas não lineares e sua formulação considera as coordenadas nodais como variáveis do sistema estrutural em vez dos deslocamentos. O comportamento constitutivo do material é descrito por um modelo elástico linear. Aplicações numéricas de duas treliças encontradas na literatura são fornecidas para comprovar o desempenho computacional do algoritmo na obtenção da trajetória de equilíbrio. As simulações são realizadas com o programa livre Scilab.
ЛЕКСИКОГРАФІЧНА ІНТЕПРЕТАЦІЯ ФЕМІНІТИВІВ У СУЧАСНІЙ УКРАЇНСЬКІЙ ЛІТЕРАТУРНІЙ МОВІ
Authors: Брус М. П.
Published: August 2022

У статті проаналізовано здобутки з лінгвоукраїністики, що втілили особливості словникового впорядкування фемінітивної лексики, відзначено спробу укладання спеціального історичного словника найменувань жінок. Увагу спрямовано на те, щоб зняти різнобічність у визначенні статусу фемінітивів як самостійних лексем, довести необхідність тлумачення їх як окремих реєстрових одиниць, розглянути словотвірну похідність фемінітивів та відбиття її в словнику, умотивувати зумовленість стилістичного статусу найменувань жінок мовними й позамовними історичними змінами
ЛОКАТИВНА ФУНКЦІЯ РОДОВОГО ВІДМІНКА: УКРАЇНСЬКО -РОСІЙСЬКІ АСИМЕТРІЙНІ ЗВ’ЯЗКИ
Authors: Степаненко Н. С.
Published: August 2022

У статті в компаративному плані з’ясовано семантичну диференціацію локативності, закріплену за родовим відмінком української та російської мов. Установлено збіжності, що стосуються конкретних значень із просторовою детермінацією і прийменникового складу конструкцій, утворених за моделлю V + Prep + Ngen. Основну увагу приділено характеристиці асиметрійності на рівні окремих прийменників і прийменниково-відмінкових структур. Удокладнено проаналізовано значеннєвий обсяг, лексико-семантичну будову, стилістичний потенціал, синтагматичні можливості українських синтаксем V + З-НАД + Ngen, V + З-ПЕРЕД + Ngen, V + З-ПОПЕРЕД + Ngen, V + З-ПОМІЖ + Ngen, V + З-МІЖ + Ngen, V + З-МЕЖИ + Ngen,V + З-ПРОМІЖ + Ngen, V + З-ПОМЕЖИ + Ngen, V + ПЕРЕД + Ngen.
НЕВЛАСНЕ ПИТАЛЬНІ БЕЗОСОБОВО-ІНФІНІТИВНІ РЕЧЕННЯ В АСПЕКТІ ГРАМАТИКИ ОЦІНКИ
Authors: Халіман О. В.
Published: August 2022

У статті схарактеризовано особливості вживання невласне питальних безособово-інфінітивних речень (модель “чого / чому / для чого / навіщо Inf?”) як продуктивної моделі реалізації оцінної функції. Аксіологічну маркованість досліджуваної конструкції забезпечують (а) уживання інфінітивної форми у вторинній функції; (б) реалізація непитального суб’єктивно-модального значення питальною конструкцією. Названу дієсловом-інфінітивом дію мовець кваліфікує як недоречну, оцінює негативно. У межах конструкції описано підтипи за здійсненістю / нездійсненістю дії та за спрямованістю висловлювання з більш детальною диференціацією кожного з них.
ТИПИ ПАРАДИГМ У ПАРАДИГМАТИЧНОМУ АНАЛІЗІ ТЕКСТУ
Authors: Myroshnychenko M. P.
Published: August 2022

Статтю присвячено дослідженню типів парадигм, що виділяються на різних етапах розуміння тексту й створюють основу для аналізу його змісту та формування типології ідіостилів у процесі парадигматичного аналізу. Парадигматичний аналіз розглядаємо як аналог сприйняття тексту читачем. У процесі сприйняття тексту читач переходить від слів як одиниць мови до немовних когнітивних одиниць – образів, понять та емоцій. Немовні когнітивні одиниці в процесі сприйняття пов’язуються одна з одною як різні визначення одного або близьких понять в один ряд – парадигму. Зміст тексту за своєю суттю варіативний та визначається як особливостями реципієнта, так і особливостями організації форми тексту. Такий підхід до його змісту вимагає розробки адекватних методів його аналізу. У статті розглянуто особливості різних типів парадигм для створення і розширення інструментарію дослідника в процесі аналізу тексту. Під час вивчення дослідницької літератури, у якій застосовується метод парадигматичного аналізу у функційному аспекті, було виділено такі типи парадигм, як номінативні та домінантні, внутришньотекстові та міжтекстові (міжтекстові парадигми також можуть бути міжідеостильовими), експліцитні та імпліцитні. Серед імпліцитних парадигм виділяємо інтертекстуальні (або внутрішньотекстові), міжтекстові (на матеріалі творчості письменника) та екстратекстові (виокремлюємо за допомогою інформації поза межами творчості автора). Доходимо висновку, що виділення домінантних і номінативних парадигм дає змогу створити аналог композиції сприйняття тексту читачем. Розширення текстового простору та вихід за межі досліджуваного тексту уможливлює деталізування досліджуваних явищ: виділення екстратекстових, інтертекстових і міжтекстових імпліцитних парадигм може бути необхідною умовою для виявлення прихованого змісту тексту. Оцінка парадигм як імпліцитних або експліцитних доповнює дослідження специфіки ідіостилю письменника.