bluuebunny/crossref_metadata_2025 huggingface dataset:
Wavelength-Parallel Photonic Tensor Core Based on Multi-FSR Microring Resonator Crossbar Array
Authors: Xiao Xian , Cheung Stanley , Hooten Sean , Peng Yiwei , Tossoun Bassem , Van Vaerenbergh Thomas , Kurczveil Geza , Beausoleil Raymond G.
Published: May 2023

This paper proposes a wavelength-parallel photonic tensor core by exploiting multiple free spectral ranges (multi-FSRs) of the microring resonator crossbar array architecture. As an example, a four-FSR 4×4 crossbar array is designed and simulated.
A Modified Mesh with Individually Monitored Interferometers for Fast Programmable Optical Processors
Authors: Mojaver Kaveh (Hassan) Rahbardar , Zhao Bokun , Liboiron-Ladouceur Odile
Published: May 2023

We demonstrate a novel mesh of interferometers for programmable optical processors. Employing an efficient programming scheme, the proposed architecture improves energy efficiency by 83% maintaining the same computation accuracy for weight matrix changes at 2 kHz.
Field Trial of Coexistence and Simultaneous Switching of Real-time Fiber Sensing and 400GbE Supporting DCI and 5G Mobile Services
Authors: Huang Yue-Kai , Wang Zehao , Ip Ezra , Qi Zhenzhou , Zussman Gil , Kilper Dan , Asahi Koji , Kageshima Hideo , Aono Yoshiaki , Chen Tingjun
Published: May 2023

Coexistence of real-time constant-amplitude distributed acoustic sensing (DAS) and 400GbE signals is verified by field trial over metro fibers, demonstrating no QoT impact during co-propagation and supporting preemptive DAS-informed optical path switching before link failure.
Service Margins for Wide-Band Optical Spectrum Services Implemented in Long-Haul Raman-Enabled Networks
Authors: Kaeval Kaida , Patri Sai Kireet , Pedreno-Manresa Jose-Juan , Grobe Klaus , Elbers Jörg-Peter , Griesser Helmut , Tikas Marko , Jervan Gert
Published: May 2023

Operators depend on reliable Q-margin estimates to reliably operate wide-band Optical Spectrum Services. We use long-term performance tracking in live Raman-enabled links to derive service margins for a 375-GHz Optical Spectrum Service.
Plasmonic Modulators for Future Highest-Speed Free Space Optical Communications
Authors: Kulmer Laurenz , Horst Yannik , Bitachon Bertold I. , Destraz Marcel , Blatter Tobias , Rimlinger Matthieu , Keller Killian , Tedaldi Valentino , Habegger Patrick , De Leo Eva , Heni Wolfgang , Hoessbacher Claudia , Montmerle-Bonnefois Aurélie , Lim Caroline B. , Conan Jean-Marc , Montri Joseph , Sorrente Beatrice , Perrault Philippe , Petit Cyril , Védrenne Nicolas , Pommarel Loann , Lindberg Hannah , Francou Laurent , Matter Daniel , Le Kernec Arnaud , Maho Anaëlle , Lévêque Simon , Sotom Michael , Baeuerle Benedikt , Leuthold Juerg
Published: May 2023

Plasmonic modulators have been assessed for operation up to 200 GBaud in a turbulent 53 km free-space-optical link. They are shown to withstand space radiation and large temperature ranges making them ideal for space applications.
High Data Rate Optical Wireless Communication over Wide Range by Using Nonuniform-space Optical Phased Array
Authors: Li Yingzhi , Chen Baisong , Na Quanxin , Luo Xianshu , Lo Guo-qiang , Xie Qijie , Song Junfeng
Published: May 2023

We demonstrate a high-data-rate optical wireless communication (OWC) system over wide steering range by using a nonuniform-space optical-phased-array (OPA) chip. More than 70 Gb/s data transmission covering 100° steering range over 10 m is achieved.
Mitigation of Atmospheric Turbulence in an Optical Free Space Link with an Integrated Photonic Processor
Authors: Morichetti F. , Cavicchioli G. , Martinez A. , Seyedinnavadeh S. , Zanetto F. , Mazzucco C. , Re M. , Mattivi M. , Morandi F. , D’Acierno A. , Spagnolini U. , Melloni A.
Published: May 2023

Mitigation of turbulence in a Free Space Optical communication link is demonstrated using an integrated programmable optical processor. 10Gbit/s OOK signals are successfully transmitted on an indoor setup emulating hundreds of meters link.
Frequency averaging with rotation angle tracking technique in phase-OTDR DAS for large-scale vibration measurement
Authors: Wakisaka Yoshifumi , Takahashi Hiroshi , Iida Daisuke , Ishimaru Takahiro , Koshikiya Yusuke
Published: May 2023

Sensitivity degradation specific to frequency-multiplexed phase OTDR in measuring large strain change is clarified for the first time. We demonstrate one solution based on frequency averaging with rotation angle tracking technique to measure sub-εµ vibrations.
Simultaneous Temperature and Acoustic Sensing with Coherent Correlation OTDR
Authors: Sandmann André , Azendorf Florian , Eiselt Michael
Published: May 2023

Superimposed temperature variations and dynamic strain applied through a 400 Hz acoustic signal on a 195 m single-mode fiber section are successfully measured using a coherent correlation optical time domain reflectometry as an interrogator.
Hybrid coding Ultra-weak Fiber Bragg Grating (UWFBG) Array for High Spatial Resolution Temperature Sensing
Authors: Xiao Xiangpeng , Song Qingguo , Zhao Weiliang , Li Hao , Sun Qizhen , Yan Zhijun
Published: May 2023

An UWFBG array containing 1000 UWFBGs spaced 10cm apart by time and wavelength division multiplexing was fabricated in UV-transparent coating optical fiber. The temperature sensing precision is around 0.1℃ under 1pm wavelength measuring accuracy.
Simultaneous Measurement of Temperature and Strain with Enhanced Accuracy by Using Forward Brillouin Scattering in Highly Nonlinear Fiber
Authors: Yang Guijiang , Zeng Keyan , Wang Liang , Tang Ming , Liu Deming
Published: May 2023

Simultaneous temperature and strain sensing has been demonstrated for the first time by using forward Brillouin scattering in highly nonlinear fiber. The accuracy is improved by seven times compared with that using backward Brillouin scattering.
Fast BOTDA acquiring method based on broadband light as a probe signal
Authors: Ishimaru Takahiro , Wakisaka Yoshifumi , Takahashi Hiroshi , Iida Daisuke , Koshikiya Yusuke
Published: May 2023

We propose a fast BOTDA-based large dynamic strain measurement technique with a broadband ASE probe light. We demonstrate the distributed measurement of 25 Hz vibration with the 380 µε amplitude.
Solving the Escape Density Problem: Making connections count with SCIP
Authors: Schaevitz Rebecca Kayla , Muth Karl , Luo Ying , Raghuraman Vivek , Margalit Near
Published: May 2023

Silicon Photonics Chiplets in Package (SCIP) creates a paradigm shift, enabling escape densities in optics that match the core silicon and creating a scalable platform that meets requirements of future data center and compute architectures.
Lithium-niobate-based narrow-linewidth frequency agile integrated lasers with petahertz frequency tuning rate
Authors: Snigirev Viacheslav , Riedhauser Annina , Lihachev Grigory , Riemensberger Johann , Wang Rui Ning , Möhl Charles , Churaev Mikhail , Siddharth Anat , Huang Guanhao , Popoff Youri , Drechsler Ute , Caimi Daniele , Hönl Simon , Liu Junqiu , Seidler Paul , Kippenberg Tobias J.
Published: May 2023

We demonstrate an electro-optically tunable hybrid integrated laser self-injection locked to a mode of a heterogeneously integrated lithium-niobate-on-Damascene-silicon-nitride microresonator. An intrinsic linewidth of 3 kHz and a frequency tuning rate of 12 × 1015 Hz/s were observed. Proof-of-principle coherent LiDAR experiments were performed.
Longitudinal Non-Destructive Characterization of Nested Antiresonant Nodeless Fiber Microstructure Geometry and Twist
Authors: Budd Leonard , Taranta Austin , Fokoua Eric Numkam , Poletti Francesco
Published: May 2023

We demonstrate non-destructive measurement of nested antiresonant nodeless fiber ( NANF) m icrostructure a long 2 .2 k m o f fi ber us ing a si de-scattering method. Additionally, using the same technique, we demonstrate measurement of twisting in NANF.
Dispersion Compensation over C-band WDM Grid for 100Gb/s PAM4 System by Low-complexity Optoelectronic Feedforward Equalization (OE-FFE)
Authors: Zhu Paikun , Yoshida Yuki , Kanno Atsushi , Akahane Kouichi , Kitayama Ken-ichi
Published: May 2023

We experimentally investigate OE-FFE-enabled C-band 100Gb/s/λ PAM4 transmission over 50km with different carrier frequencies and linewidths. 3.8-THz range on ITU-T G.694.1 grid is supported with a single 1-tap optical delay line and ≤32-tap digital FFE.
Efficient Transport of eCPRI Fronthaul over PON
Authors: Maes Jochen , Bidkar Sarvesh , Straub Michael , Pfeiffer Thomas , Bonk Rene
Published: May 2023

Passive optical networks (PONs) facilitate small cell deployments. Back- and midhaul already make efficient use of PON. We explain the steps taken in mobile and in PON industries to enable efficient eCPRI fronthaul over PON.
CompQoTE: Generalizing QoT Estimation with Composable ML and End-to-End Learning
Authors: Gao Hanyu , Chen Xiaoliang , Sun Lu , Li Zhaohui
Published: May 2023

This paper proposes CompQoTE, a composable QoT estimation design with end-to-end learning capability. Results show CompQoT can generalize arbitrary lightpaths while achieving > 90% estimation accuracy for unseen lightpaths.
Traffic Prediction Based on P-ConvLSTM in Optical Transport Networks
Authors: Qin Xin , Hu Qian , Huo Xiaoli , Xie Jiuyu
Published: May 2023

Based on Prophet-guided neural network, P-ConvLSTM is proposed for traffic prediction. Proved by multi-group real traffic data in OTN, P-ConvLSTM has high accuracy and strong generalization.
Digital Twin of Unrepeatered Line Based on Raman and Remote Optically Pumped Amplifier Machine Learning Models
Authors: Minakhmetov Arthur , Prieur Benjamin , Le Monnier Maël , Rouvillain Delphine , Lavigne Bruno
Published: May 2023

We demonstrate an accurate digital representation of an unrepeatered line based on separate measurement-based machine learning models of Remote Optically Pumped Amplifier and Raman amplification. We assess the accuracy via OSNR measurements in the line.
Multi-User Entanglement Routing for Quantum Mesh Networks
Authors: Sutcliffe Evan , Hoban Matty J. , Beghelli Alejandra
Published: May 2023

Multipath routing for sharing entanglement between multiple devices was simulated on real network topologies and compared against single-path routing. Results show improved entanglement rates, especially for topologies with a higher average nodal degree.
Optimum Switching Scenario Analysis in a Dynamic Entanglement Network
Authors: Wang R. , Clark M. J. , Joshi S. K. , Bahrani S. , Alia O. , Peranić M. , Lončarić M. , Stipčević M. , Rarity J. , Nejabati R. , Simeonidou D.
Published: May 2023

We investigate the performance of a dynamical entanglement-based QKD network with various switching scenarios. The simulation results suggest the optimum scenario for different heralding efficiencies and detectors’ jitter and the experimental results verify the benefit.
London Quantum-Secured Metro Network
Authors: Lord Andrew , Woodward Robert , Murai Shinya , Sato Hideaki , Dynes James , Wright Paul , White Catherine , Davey Russell , Wilkinson Mark , Clinton-Tarestad Piers , Hawkins Ian , Farrington Kristopher , Shields Andrew
Published: May 2023

We describe a London Quantum-Secured Metro Network using Quantum Key Distribution between three London nodes together with customer access tails. The commercially- ready solution is fully integrated into the BT network and on-boarded its first customer.
Commentary on a Classic JHC Article on the Development of Highly Sensitive Fluorochrome-labeled Tyramides for Immunocytochemistry
Authors: Roth Kevin A.
Published: May 2023

This commentary reflects on the significance and impact of the highly cited companion article that was published in the Journal of Histochemistry and Cytochemistry in 1997 (Gijlswijk RPM et al. Fluorochrome-labeled Tyramides: Use in Immunocytochemistry and Fluorescence In Situ Hybridization. Journal of Histochemistry & Cytochemistry. 1997;45(3):375-382):
Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast
Authors: Xu Yong-jie , Bhadra Sankhadip , Mahdi Alaa Taha A. , Dev Kamal , Yurtsever Ilknur , Nakamura Toru M.
Published: May 2023

Replication protein A (RPA) is a heterotrimeric complex and the major single-strand DNA (ssDNA) binding protein in eukaryotes. It plays important roles in DNA replication, repair, recombination, telomere maintenance, and checkpoint signaling. Because RPA is essential for cell survival, understanding its checkpoint signaling function in cells has been challenging. Several RPA mutants have been reported previously in fission yeast. None of them, however, has a defined checkpoint defect. A separation-of-function mutant of RPA, if identified, would provide significant insights into the checkpoint initiation mechanisms. We have explored this possibility and carried out an extensive genetic screen for Rpa1/Ssb1, the large subunit of RPA in fission yeast, looking for mutants with defects in checkpoint signaling. This screen has identified twenty-five primary mutants that are sensitive to genotoxins. Among these mutants, two have been confirmed partially defective in checkpoint signaling primarily at the replication fork, not the DNA damage site. The remaining mutants are likely defective in other functions such as DNA repair or telomere maintenance. Our screened mutants, therefore, provide a valuable tool for future dissection of the multiple functions of RPA in fission yeast.
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity
Authors: Yu Meigen , Ye Hui , De-Paula Ruth B. , Mangleburg Carl Grant , Wu Timothy , Lee Tom V. , Li Yarong , Duong Duc , Phillips Bridget , Cruchaga Carlos , Allen Genevera I. , Seyfried Nicholas T. , Al-Ramahi Ismael , Botas Juan , Shulman Joshua M.
Published: May 2023

Heterozygous variants in the glucocerebrosidase (GBA) gene are common and potent risk factors for Parkinson’s disease (PD). GBA also causes the autosomal recessive lysosomal storage disorder (LSD), Gaucher disease, and emerging evidence from human genetics implicates many other LSD genes in PD susceptibility. We have systemically tested 86 conserved fly homologs of 37 human LSD genes for requirements in the aging adult Drosophila brain and for potential genetic interactions with neurodegeneration caused by α-synuclein (αSyn), which forms Lewy body pathology in PD. Our screen identifies 15 genetic enhancers of αSyn-induced progressive locomotor dysfunction, including knockdown of fly homologs of GBA and other LSD genes with independent support as PD susceptibility factors from human genetics (SCARB2, SMPD1, CTSD, GNPTAB, SLC17A5). For several genes, results from multiple alleles suggest dose-sensitivity and context-dependent pleiotropy in the presence or absence of αSyn. Homologs of two genes causing cholesterol storage disorders, Npc1a / NPC1 and Lip4 / LIPA, were independently confirmed as loss-of-function enhancers of αSyn-induced retinal degeneration. The enzymes encoded by several modifier genes are upregulated in αSyn transgenic flies, based on unbiased proteomics, revealing a possible, albeit ineffective, compensatory response. Overall, our results reinforce the important role of lysosomal genes in brain health and PD pathogenesis, and implicate several metabolic pathways, including cholesterol homeostasis, in αSyn-mediated neurotoxicity.
Evaluation of two red cell inclusion staining methods for assessing spleen function among sickle cell disease patients in North-East Nigeria
Authors: Ladu Adama I. , Satumari Ngamarju A. , Abba Aisha M. , Abulfathi Fatima A. , Jeffery Caroline , Adekile Adekunle , Bates Imelda
Published: May 2023

The loss of splenic function is associated with an increased risk of infection in sickle cell disease (SCD); however, spleen function is rarely documented among SCD patients in Africa, due partly to the non-availability of sophisticated techniques such as scintigraphy. Methods of assessing splenic function which may be achievable in resource-poor settings include counting red blood cells (RBC) containing Howell Jolly Bodies (HJB) and RBC containing silver-staining (argyrophilic) inclusions (AI) using a light microscope. We evaluated the presence of HJB—and AI—containing RBC as markers of splenic dysfunction among SCD patients in Nigeria. We prospectively enrolled children and adults with SCD in steady state attending outpatient clinics at a tertiary hospital in North-East Nigeria. The percentages of HJB—and AI-containing red cells were estimated from peripheral blood smears and compared to normal controls. There were 182 SCD patients and 102 healthy controls. Both AI- and HJB-containing red cells could be easily identified in the participants blood smears. SCD patients had a significantly higher proportion of red cells containing HJB (1.5%; IQR 0.7%–3.1%) compared to controls (0.3%; IQR 0.1%–0.5%) (P <0.0001). The AI red cell counts were also higher among the SCD patients (47.4%; IQR 34.5%–66.0%) than the control group (7.1%; IQR 5.1%–8.7%) (P < 0.0001). The intra-observer reliability for assessment of HJB- (r = 0.92; r2 = 0.86) and AI- containing red cells (r = 0.90; r2 = 0.82) was high. The estimated intra-observer agreement was better with the HJB count method (95% limits of agreement, -4.5% to 4.3%; P = 0.579).We have demonstrated the utility of light microscopy in the assessment of red cells containing—HJB and AI inclusions as indices of splenic dysfunction in Nigerian SCD patients. These methods can be easily applied in the routine evaluation and care of patients with SCD to identify those at high risk of infection and initiate appropriate preventive measures.
Young, but not in the dark—The influence of reduced lighting on gait stability in middle-aged adults
Authors: Naaman Tirtsa , Hayek Roee , Gutman Itai , Springer Shmuel
Published: May 2023

Background

The aim of this study was to investigate the effects of walking in reduced lighting with or without performing a secondary cognitive task on gait dynamics in middle-aged adults and to compare them with young and old adults.

Methods

Twenty young (age 28.8±4.1), 20 middle-aged (age 50.2±4.4), and 19 elderly (age 70.7±4.2) subjects participated in the study. Subjects walked on an instrumented treadmill at a self-determined pace under four conditions in randomized order: (1) walking in usual lighting (1000 lumens); (2) walking in near-darkness (5 lumens); (3) walking in usual lighting with a serial-7 subtraction dual-task; and (4) walking in near-darkness with a serial-7 subtraction dual-task. Variability in stride time and variability in the trajectory of the center of pressure in the sagittal and frontal planes (anterior/posterior and lateral variability) were measured. Repeated measures ANOVA and planned comparisons were used to determine the effects of age, lighting conditions, and cognitive task on each gait outcome.

Results

Under usual lighting, stride time variability and anterior/posterior variability of the middle-aged subjects were similar to those of the young and lower than those of the old. The lateral variability of the middle-aged subjects was higher than that of young adults under both lighting conditions. Similar to the older adults, the middle-aged participants increased their stride time variability when walking in near-darkness, but they were the only ones to exhibit increased lateral variability and anterior/posterior variability in near-darkness. Young adult gait was not affected by lighting, and concurrent performance of a cognitive task while walking did not affect gait stability in all groups under any of the lighting conditions.

Conclusions

Gait stability decreases in middle age when walking in the dark. Recognition of functional deficits in middle age could promote appropriate interventions to optimize aging and reduce fall risk.
The association of denture wearing with reduced lung function and increased airflow limitation in 58–72 year old men
Authors: Kelly Niamh , Gormley Kyra , Linden Dermot A. , Winning Lewis , McClory Mary , Lundy Fionnuala T. , Cullen Kathy M. , Linden Gerard J. , El Karim Ikhlas A.
Published: May 2023

Objective

To investigate the association between denture wearing and airflow limitation in men in Northern Ireland enrolled in the Prospective Epidemiological Study of Myocardial Infarction (PRIME) study.

Methods

A case-control design was used to study partially dentate men. Cases were men aged 58–72 years who were confirmed as denture wearers. Controls were never denture wearers who were matched by age (± 1 month) and smoking habit to the cases. The men had a periodontal assessment and completed a questionnaire detailing their medical history, dental history and behaviours, social circumstances, demographic background and tobacco use. Physical examination and spirometry measurements of forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) were also undertaken. Spirometry data for edentulous men who wore complete dentures were compared with that recorded for the partially dentate men studied.

Results

There were 353 cases who were partially dentate and were confirmed denture wearers. They were matched for age and smoking habit to never denture wearer controls. The cases had an FEV1 that was on average 140 ml lower than the controls, p = 0.0013 and a 4% reduction in percent predicted FEV1, p = 0.0022. Application of the GOLD criteria indicated that 61 (17.3%) of the cases had moderate to severe airflow limitation compared with 33 (9.3%) of controls, p = 0.0051. Fully adjusted multivariable analysis showed that partially dentate men who were denture wearers were significantly more likely (p = 0.01) to have moderate to severe airflow reduction with an adjusted odds ratio (OR) of 2.37 (95% confidence intervals 1.23–4.55). In the 153 edentulous men studied moderate to severe airflow limitation was recorded in 44 (28.4%), which was significantly higher than in the partially dentate denture wearers (p = 0.017), and the men who had never worn a denture (p<0.0001).

Conclusion

Denture wearing was associated with an increased risk of moderate to severe airflow limitation in the cohort of middle-aged Western European men studied.
A qualitative assessment of factors contributing to Spanish-speaking federally qualified health center patients’ chronic pain experiences
Authors: Bifulco Lauren , Almonte Sarahí , Sosa Shantel , Etemad Leila , Ruiz Destiny , Blankson Mary L.
Published: May 2023

People of Hispanic or Latino ethnicity (Latinx people) experience pain diagnosis, treatment, and care disparities relative to non-Latinx Whites. Those whose preferred language is Spanish may experience additional disparities when receiving care in a language-discordant environment. In order to better understand medically underserved Spanish-speaking Latinx patients’ pain care experience in primary care, we conducted semi-structured qualitative interviews with federally qualified health center staff members (n = 9) and Spanish-speaking adult Latinx patients with chronic pain (n = 12) to capture data on their perspectives. Interview data were mapped to the individual (microsystem), interpersonal (mesosystem), organizational (exosystem), and environmental (macrosystem) levels of Bronfenbrenner’s Ecological Systems Theory and analyzed using thematic content analysis informed by the Framework Method. Findings suggest that Spanish-speaking patients and English-speaking care team members may interpret information about pain state and severity differently, may have misaligned expectations about care, treatment methodologies, and treatment goals, and may experience difficulty forming a mutual understanding during health care encounters due to cross-linguistic and cross-cultural miscommunication. Patients preferred to describe their pain in words rather than with numbers or standardized scales, and both patients and frontline care team members expressed frustration with medical interpretation services, which added time and complexity to visits. Patients and health center staff emphasized the diversity of experiences among Spanish-speaking Latinx people, and the need to account for both linguistic and cultural differences during care encounters. Both groups supported hiring more Spanish-speaking, Latinx healthcare personnel who better resemble the patient population, which has the potential to improve linguistic and cultural concordance and competence, with the aim of improving care outcomes and patient satisfaction. Further study is warranted to examine how linguistic and cultural communication barriers impact pain assessment and treatment in primary care, the extent to which patients feel understood by their care teams, and their confidence in their ability to understand and interpret treatment recommendations.
Predictors of glaucoma knowledge and its risk factors among Jordanian patients with primary open angle glaucoma at a tertiary teaching hospital: A cross-sectional survey
Authors: Muhsen Sana’ , Al-Huneidy Leen , Maaita Ward , AlQirem Lina , Madain Zaid , Sweis Jaleel , Abu Tawileh Raya , Al-Huneidy Yazan , Alkhatib Amro , Al-Ani Abdallah
Published: May 2023

Purpose of study

To assess and compare glaucoma knowledge between Jordanian patients with glaucoma and non-glaucoma ophthalmic patients.

Methods

A cross-sectional survey was developed after an extensive literature search to investigate glaucoma-related knowledge among participants with glaucoma visiting the Jordan University Hospital clinics from October 2021 to February 2022. Responses were compared to a sample of ophthalmic participants with eye conditions other than glaucoma visiting the ophthalmology clinics at the same time frame.

Results

A total of 256 participants filled out the survey, of which 53.1% were diagnosed with glaucoma while 46.9% had ophthalmic conditions other than glaucoma. Our sample of participants is characterized by a mean age of 52.2 ± 17.8 years and a male-to-female ratio of 1.04:1. Overall, participants with glaucoma were more aware of their disease than participants with other ophthalmic conditions. Compared to their ophthalmic non-glaucoma counterparts, those diagnosed with glaucoma face significantly more daily life difficulties due to their ophthalmic disease (p <0.001). Results of the independent samplet-test demonstrate that participants with glaucoma have significantly higher knowledge scores (p <0.001) and were able to recognize more glaucoma symptoms than their non-glaucoma counterparts (p = 0.002). Similarly, those with a positive family history of glaucoma displayed higher knowledge (p = 0.005). Multivariate linear regression demonstrates that family history of glaucoma, higher symptom recognition score, reliance on ophthalmologists, and the internet for glaucoma-related information are positive predictors of higher knowledge scores.

Conclusion

We have demonstrated that both glaucoma and non-glaucoma ophthalmic patients display average levels of glaucoma knowledge. Raising awareness through various interventions may improve the lifestyles of patients with glaucoma and alleviate the economic burden associated with treating the disease.
Devising novel performance measures for assessing the behavior of multilayer perceptrons trained on regression tasks
Authors: Armano Giuliano , Manconi Andrea
Published: May 2023

This methodological article is mainly aimed at establishing a bridge between classification and regression tasks, in a frame shaped by performance evaluation. More specifically, a general procedure for calculating performance measures is proposed, which can be applied to both classification and regression models. To this end, a notable change in the policy used to evaluate the confusion matrix is made, with the goal of reporting information about regression performance therein. This policy, called generalized token sharing, allows to a) assess models trained on both classification and regression tasks, b) evaluate the importance of input features, and c) inspect the behavior of multilayer perceptrons by looking at their hidden layers. The occurrence of success and failure patterns at the hidden layers of multilayer perceptrons trained and tested on selected regression problems, together with the effectiveness of layer-wise training, is also discussed.
Stigmatization profiles and psychological distress in people at high risk of infection with COVID-19 –A study conducted in Germany from March to August 2021
Authors: Bisenius Sandrine , Treml Julia , Hanschmidt Franz , Kersting Anette
Published: May 2023

COVID-19-related stigmatization of affected people or people at risk of infection has been shown to enhance the reluctance of affected individuals to use health services and reduce their mental health. It is thus highly important to gain a thorough understanding of COVID-19-related stigmatization. The present study’s first aim was to explore stigmatization profiles of experienced stigmatization (anticipated stigmatization, internalized stigmatization, enacted stigmatization, disclosure concerns) and stigmatization practices in 371 German people at high risk of infection using latent class analyses. The second aim was to investigate the relationship between stigmatization profiles and psychological distress via multiple regression analysis taking into account other possible negative and positive risk factors. Our results showed two stigmatization profiles: "high stigmatization group" and "low stigmatization group". Belonging to the "high stigmatization group" was significantly correlated with higher levels of psychological distress. Other risk factors significantly related to psychological distress were mental health disorders in the past, exposure to COVID-19, fear related to COVID-19, perceived risk of being infected, lower perceived self-efficacy, and lower subjective knowledge about COVID-19.
COVID-19-related social isolation and symptoms of depression and anxiety in young men in Poland: Does insomnia mediate the relationship?
Authors: Mojsa-Kaja Justyna , Szklarczyk-Smolana Klaudia , Niedzielska-Andres Ewa , Kurpińska Anna , Suraj-Prażmowska Joanna , Walczak Maria
Published: May 2023

The need for physical distancing due to COVID-19 mitigation efforts forced prolonged social isolation, which may affect sleep and lead to mental health problems. Previous research has shown that young adults are particularly vulnerable to psychological stress caused by social isolation, the negative psychological impact of the pandemic, and greater frequency and severity of sleep problems. Therefore, the main goal of the present study was to examine whether insomnia could constitute a mediation mechanism that explains the relationship between social isolation experienced during the COVID-19 pandemic and mental health outcomes (depression and anxiety) reported up to 1.5 years later. The study was conducted among young (M±SD; 24.08±3.75) men (N = 1025) in Poland. Data were collected by means of self-report questionnaires, including The Social Isolation Index, The Athens Insomnia Scale, The State-Trait Anxiety Inventory (STAI-S) and Beck’s Depression Inventory (BDI-II). The results show that insomnia mediates the relationships between social isolation and both anxiety and depression. The current findings emphasize the role of insomnia in the relationships between social isolation experienced during COVID-19 and negative emotional states. From a clinical perspective, the results suggest that implementing therapeutic components that address social isolation in insomnia treatment programs may prevent the development of depression and anxiety symptoms among young men.
Validation of automatic monitoring of feeding behaviours in sheep and goats
Authors: Berthel Roxanne , Deichelboher Alisha , Dohme-Meier Frigga , Egli Wendelin , Keil Nina
Published: May 2023

Monitoring the feeding and ruminating behaviour of ruminants can be used to assess their health and welfare. The MSR-jaw movement recording system (JAM-R) can automatically record the jaw movements of ruminants. The associated software Viewer2 was developed to classify these recordings in adult cattle and calculate the duration and number of mastications of feeding and ruminating. The purpose of this study was to evaluate the performance of Viewer2 in classifying the behaviour of sheep and goats and assessing their feeding and ruminating. The feeding and ruminating behaviour of ten sheep and ten goats on pasture (observed live) and of five sheep and five goats in the barn (observed by video) were compared with Viewer2 behaviour classifications. To assess the technical and welfare issues of the JAM-R, its application was tested in a feeding experiment with 24 h monitoring of the feeding behaviours of 24 sheep and 24 goats. Viewer2 worked equally well on both species. The mean (95% confidence interval) performance of Viewer2 was at a good level for feeding (accuracy: 0.8–1.0; sensitivity: 0.9–1.0; specificity: 0.6–0.9; precision: 0.7–0.9) and ruminating (accuracy: 0.8–0.9; sensitivity: 0.6–0.8; specificity: 0.8–1.0; precision: 0.9–1.0) compared with human observations, with minor differences between the conditions on pasture and in the barn. The performance improved when recording frequency was increased from 10 Hz to 20 Hz. Applying the JAM-R in a feeding experiment, 71% of the recordings executed were defined as technically error-free and produced plausible values for feeding behaviours. In conclusion, according to the values of accuracy, sensitivity, specificity and precision, the presented JAM-R system with Viewer2 is a reliable and applicable technology for automatic recording of feeding and ruminating behaviour of sheep and goats on pasture and in the barn.
Heat shock protein 70 protects the lungs from hyperoxic injury in a neonatal rat model of bronchopulmonary dysplasia
Authors: Lee Cheng-Han , Su Tzu-Cheng , Lee Ming-Sheng , Hsu Chien-Sheng , Yang Rei-Cheng , Kao Jun-Kai
Published: May 2023

Hyperoxia plays a significant role in the pathogenesis of lung injury, such as bronchopulmonary dysplasia (BPD), in premature infants or newborns. BPD management aims to minimize further injury, provide an optimal environment to support growth and recovery. In clinic neonatal care, we need a new therapy for BPD. Heat shock protein 70 (Hsp70) inhibit cell apoptosis and promote cell repair allowing cells to survive lethal injury. We hypothesized that Hsp70 could be used to prevent hyperoxia related BPD in the neonatal rat model through its anti-apoptotic and anti-inflammatory effects. In this study, we explored the effect of Hsp70 on hyperoxia-induced lung injury using neonatal rats. Neonatal Wistar rats were delivered naturally at full term of gestation and were then pooled and randomly assigned to several groups to receive heat stimulation (41°C for 20 min) or room temperature conditions. The Hsp70 group received recombinant Hsp70 intraperitoneally (200 μg/kg, daily). All newborn rats were placed under hyperoxic conditions (85% oxygen) for 21 days. Survival rates in both heat-hyperoxia and Hsp70-hyperoxia groups were higher than those in the hyperoxia group (p < 0.05). Both endogenous and exogenous Hsp70 could reduce early apoptosis of alveolar cells under hyperoxia. Additionally, there were less macrophage infiltration in the lung of the Hsp70 groups (p < 0.05). Heat stress, heat shock proteins, and exogenous recombinant Hsp70 significantly increased the survival rate and reduced pathological hyperoxia induced lung injuries in the development of BPD. These results suggest that treating hyperoxia-induced lung injury with Hsp70 may reduce the risk of developing BPD.
Short report: Social processing in non-emotional contexts by children with and without autism spectrum disorders (ASD)
Authors: Teh Elizabeth J. , Yap Melvin J.
Published: May 2023

Background

Children with autism spectrum disorders (ASD) have been reported to show social-processing deficits in forced-choice social judgment or story interpretation tasks. However, these methods may limit examination of social-processing within a set of acceptable answers. In this pilot study, we propose a novel method predicated on the premise that language carries social information and validate this method to measure social perception in ASD.

Method

20 children with ASD and 20 typically developing (TD) children matched-pairwise on age (5–12 years), gender, and non-verbal IQ, described pictures of people in everyday situations varying on extent of social engagement. Their social language production was examined in high- and low-social picture conditions.

Results

The TD group produced significantly more social language in high-social than low-social picture conditions, with a large effect size (d = 3.15). The TD group produced significantly more social language than the ASD group under high-social conditions (p< .001, η2p = 0.24), but were not significantly different under low-social conditions (p < .05).

Conclusions and implications

The study presents proof-of-concept that expressed language carries social information. The findings indicate that social language may be used to measure social perception and examine differences in ASD, with potential applications for other clinical groups with social-processing challenges.
Social and economic capital as effect modifiers of the association between psychosocial stress and oral health
Authors: Hensel Abby L. J. , Gomaa Noha
Published: May 2023

Objectives

To assess the extent of the association of psychosocial stress with oral health in an Ontario population stratified by age groups, and whether any association is modified by indicators of social and economic capital.

Methods

We retrieved data of 21,320 Ontario adults, aged 30–74 years old, from the Canadian Community Health Survey (CCHS: 2017–2018), which is a Canada-wide, cross-sectional survey. Using binomial logistic regression models that adjusted for age, sex, education, and country of birth, we examined the association of psychosocial stress (indicated by perceived life stress) with inadequate oral health (indicated as having at least one of the following: bleeding gums, fair/poor self-perceived oral health, persistent oral pain). We assessed the effect measure modification of indicators of social (sense of belonging to the local community, living/family arrangements) and economic capital (household income, dental insurance, dwelling ownership) on the perceived life stress-oral health relationship, stratified by age (30–44, 45–59, 60–74 yrs). We then calculated the Relative Excess Risk due to Interaction (RERI) which indicates the risk that is above what would be expected if the combination of low capital (social or economic) and high psychosocial stress was entirely additive.

Results

Respondents with higher perceived life stress were at a significantly higher risk of having inadequate oral health (PR = 1.39; 95% CI: 1.34, 1.44). Adults with low social and economic capital were also at an increased risk of inadequate oral health. Effect measure modification showed an additive effect of indicators of social capital on the perceived life stress-oral health relationship. This effect was evident across all three age groups (30–44, 45–59, 60–74 yrs), with the highest attributable proportion of social and economic capital indicators in the psychosocial stress-oral health relationship in older adults (60–74 yrs).

Conclusion

Our findings suggest an exacerbating effect for low social and economic capital in the relationship of perceived life stress with inadequate oral health among older adults.
A theoretical model of factors influencing online consumer purchasing behavior through electronic word of mouth data mining and analysis
Authors: Wang Qiwei , Zhu Xiaoya , Wang Manman , Zhou Fuli , Cheng Shuang
Published: May 2023

The coronavirus disease 2019 pandemic has impacted and changed consumer behavior because of a prolonged quarantine and lockdown. This study proposed a theoretical framework to explore and define the influencing factors of online consumer purchasing behavior (OCPB) based on electronic word-of-mouth (e-WOM) data mining and analysis. Data pertaining to e-WOM were crawled from smartphone product reviews from the two most popular online shopping platforms in China, Jingdong.com and Taobao.com. Data processing aimed to filter noise and translate unstructured data from complex text reviews into structured data. The machine learning based K-means clustering method was utilized to cluster the influencing factors of OCPB. Comparing the clustering results and Kotler’s five products level, the influencing factors of OCPB were clustered around four categories: perceived emergency context, product, innovation, and function attributes. This study contributes to OCPB research by data mining and analysis that can adequately identify the influencing factors based on e-WOM. The definition and explanation of these categories may have important implications for both OCPB and e-commerce.
Meditations on teaching drawing and movement as ‘mind in motion’
Authors: Simmons Seymour
Published: May 2023

In this paper, I take the theme ‘Drawing and Movement’ as an opportunity to reflect on relationships between mind and body in learning how to draw as fostered by diverse teaching methods. Towards that end, I initially propose a cognitive perspective based on Barbara book, Mind in Motion, then apply it to two movement-intensive drawing skills – mark or pattern-making and figurative sketching, each with an imperative for practice. In the process, the concept of ‘mind in motion’ helps shed new light on five instructional paradigms I defined in my previous research. To conclude, I review conditions in contemporary culture and visual arts education that make the restoration of drawing instruction as outlined here especially relevant in the digital age. Connecting these sections, I will highlight eight drawing demonstrations to illustrate how ‘mind in motion’ helps explain how drawing not only represents thought in different domains (art, science, philosophy, etc.) but in fact facilitates it.
'Linescapes'
Authors: Solé Coromina Laia
Published: May 2023

En la práctica del caminar y en poner el pensamiento a la deriva se encuentra el origen de esta investigación que aborda el pensamiento gráfico en tiempos de densificación del universo visual. El encuentro como condición de lo urbano y al mismo tiempo la resonancia del pensamiento gráfico al caminar por la ciudad, detonan cuestiones como: ir al encuentro de aquello que ya está dibujado como forma de aproximarse a la ecología del trazo y la reducción de la huella; fotografiar para registrar y compartir como forma de aproximarse a la seriación y también a la redundancia de las imágenes; y las prácticas apropicionistas en el arte. El artículo adopta un relato a/r/tográfico, sensible a las formas de pensar y de hacer del arte, para indagar sobre el trazo y la huella en el contexto urbano como campo expandido del dibujo y del grabado. Aspectos relevantes en este relato son la manera en que se recogen y procesan los datos, es decir el caminar y la deriva del pensamiento. También la naturaleza híbrida y errática de los datos, que inicialmente parte de unas fotografías de la autora como forma de pensar lo gráfico, para abrirse y ponerse en relación con textos, imágenes y maneras de hacer de otras artistas y pensadoras, para terminar con el grabado como exploración del espacio.
SARGARINSKO-ALEKSEEVSKAYA CERAMICS OF THE LATE BRONZE AGE OF THE KALINOVKA-II SETTLEMENT (FOREST-STEPPE ALTAI)
Authors:   Institute of Archeology and Ethnography SB RAS, A. Fedoruk , G. Ivanov , N. Stepanova ,   Institute of Archeology and Ethnography SB RAS
Published: May 2023

The article reflects the results of a comprehensive study of the Sargarinsko-Aleksevskaya ceramics of the Kalinovka-II settlement (Eastern Kulunda). The authors analyzed the forms of vessels, ornamentation techniques, ornamental schemes, raw materials and molding masses. As a result, it was determined that the main part of the ceramics of the collection is pots. The presence of nonnumerous vessels of jar and jug-shaped forms is noted. The ceramics were decorated mainly along the neck area, less often at the shoulders. The use of six methods of applying the ornament is noted: molding, stamping, finger technique, notching, cutting and extrusion. The use of 42 ornamental motifs has been recorded. The most popular are rollers without additional decor, rows of finger prints, a herringbone of smooth stamp impressions, rows of slanted smooth stamp impressions, a horizontal herringbone roller of smooth stamp impressions and a collar with a belt of slanted impressions of the same stamp. Ornamental compositions are dominated by patterns consisting of only one motif. An analysis of the raw materials showed that vessels made from medium-ferruginous clay with fine sand (less than 0.1 mm) in high concentration predominate. Seven recipes for compiling molding masses have been identified. The tradition of adding fireclay prevails, a mixture of skills in the use of mineral impurities is recorded. Comparison of the obtained results with the materials of the settlements of the steppe and forest-steppe Altai (Zharkovo-3, Rublevo-VI, Burla-3) shows a significant similarity in the forms of vessels, ornamentation and preparation of molding masses. The studied series is similar to the ceramics of the sites of Central Kazakhstan by the similarity of forms and ornamentation, as well as the presence of a recipe that reflects the mixing of cultural traditions in the use of mineral impurities. In general, the Sargarinsko-Alekseevskaya ceramics of the Kalinovka-II settlement, as well as other sites of Altai and Kazakhstan, reflects similar processes that took place in these territories, interpenetration and contacts of the population.
90TH ANNIVERSARY OF ANATOLY IVANOVICH MARTYNOV
Authors:   Kemerovo State University, L. Kitova
Published: May 2023

The article overviews the activities of the famous Siberian archaeologist A.I. Martynov, who has been working in Kemerovo Region for 68 years. He headed the Regional Museum of Local History, explored archaeological sites of South Siberia, took part in the museumification of the archaeological rock art site “Tomskaya Pisanitsa”, and created a scientific archaeological school at Kemerovo State University. In the university, Professor A.I. Martynov established the Department of Archaeology, which he headed for 23 years. He still works at the Department of Museum Affairs at Kemerovo State Institute of Culture and at the Museum-Reserve “Tomskaya Pisanitsa”. The article also discusses the researcher’s personality traits, which enabled him to achieve outstanding results in the organization of archaeological science in the Kemerovo Region.
Mucopolisacaridosis tipo I, variante síndrome de Hurler: Abordaje inicial y relación con la literatura
Authors: Vergara Sergio , Prieto Maria Paula , Lujan Oriana , Rincones Lorena , Zannin Andreina , Arteaga Maria Ximena , Gomez Natalia , Ferrer Amenaida , Celis Luis Gustavo , Fernandez Isabel
Published: May 2023

Antecedentes: las enfermedades de depósito tipo mucopolisacaridosis son un grupo de enfermedades genéticas poco frecuentes con patrón de herencia tipo autosómico recesivo. La mucopolisacaridosis (MPS) es considerada específicamente una condición de sobrecarga lisosomal causada por deficiencias de enzimas encargadas de la degradación de glicosaminoglicanos (GAG), también llamados mucopolisacáridos; este déficit enzimático se genera de la acumulación progresiva de compuestos en diferentes tejidos que conlleva a daño tisular generalizado y que tiende a progresar a falla multiorgánica (1–5). Reporte de caso: paciente femenina lactante mayor con retraso en el neurodesarrollo y alteraciones fenotípicas notorias, lo cual se relaciona con hallazgos descritos en la literatura. Conclusiones: se identificó déficit de la enzima alfa–L-iduronidasa, en contexto de un cuadro clínico con manifestaciones severas y la edad tan temprana de inicio de la patología, se cataloga dentro de la MPS I, Síndrome de Hurler. El avance en el abordaje temprano y conocimiento en la historia natural de las enfermedades de depósito permitirá generar un mejor abordaje diagnóstico y terapéutico, generando un mejor desenlace.