bluuebunny/crossref_metadata_2025 huggingface dataset:
Улаанбаатар хотын агаарын бохирдлыг илэрхийлэгч зарим оптик параметрүүдийн жилийн явцын судалгаа (2015-2018)
Authors: Ц Баатарчулуун , Г Батсүх , Б Даариймаа , Б Жавзандолгор , Т Нарангарав , Н Түгжсүрэн
Published: March 2023

Улаанбаатар хотод 2015-2018 онд хийгдсэн нарны шулуун цацрагийн болональмункантратын хэмжилтийн өгөгдлөөр агаарын бохирдлыг илэрхийлэгч гол оптикпараметрүүд болох аэрозолын спектраль оптик зузаан болон аэрозолынхэмжээгээр түгэх түгэлтийг тодорхойлж, тэдгээрийн жилийн явцыг судлаж, өөрчлөлтхувьслын зүй тогтлыг байгаль, цаг уур, нийгмийн хүчин зүйлстэй холбон тайлбарлахоролдлого хийлээ.
ДНХ-ийн мэдээллийн үндэсний сан, “МonDIS” програм
Authors: А Баярбаатар , П Энхбаяр , Б Барсболд , Г Махгал , Ш Пүрэвдулам , Б Тэнүүн , Б Гантулга , С Ганболд
Published: March 2023

Сүүлийн жилүүдэд ШШҮХ-нд ялтны ДНХ-ийн 7000 гаруй биологийн дээж биетээрба цаасан баримтаар хуримтлагдсан. Энэхүү судалгааны хүрээнд бид MonDIS нэртэйүндэсний хэмжээний анхны ДНХ-ийн мэдээллийн сан, хайлтын системийг үүсгэнбайгуулсан ажлын үр дүнг тайлагнана. Мөн энэ чиглэлийн судалгаатай холбоотойхуримтлуулсан туршлага, цаашид гүйцэтгэх ажлыг танилцуулна.
Төвийн бүс нутгийн хөрсөн дэх 137Cs-ийн хуримтлал
Authors: Ц Сайнсанаа , Н Норов
Published: March 2023

Төвийн бүс нутгийн Дархан-Уул, Орхон, Сэлэнгэ, Төв, Өвөрхангай аймгуудынсумдын хөрсөнд үүсмэл цацраг идэвхт изотоп-137Cs-ийн хэмжээг гаммаспектрометрийн аргаар тодорхойлсон дүнг харьцуулан судалж, түүний гаммацацрагаас судалгаанд хамрагдсан сумдын оршин суугчдын жилд авах гадаадшарлагын эффектив эквивалент тунг үнэлсэн болно.
Perbandingan Nilai Kalor Biobriket dengan Variasi Komposisi Bahan Baku Limbah Biomassa
Authors: Vegatama Meita Rezki
Published: March 2023

[Comparison of The Calorific Value of Bio Briquettes with Variations in the Composition of Biomass Waste Raw Materials ]
Biomassa sebagai energi terbarukan berpeluang besar untuk kita gunakan sebagai energi terbarukan. Tempurung kelapa, sabut kelapa, dan Sekam padi merupakan limbah biomassa yang sangat potensial untuk dijadikan briket arang, ketiga bahan baku di atas memiliki nilai karbon yang cukup tinggi untuk digunakan sebagai pengganti energi yang tidak dapat diperbaharui. Penelitian ini bertujuan mengetahui nilai kalor dari masing-masing perbandingan komposisi yang telah ditetapkan. Selain nilai kalor, dalam penelitian ini juga dilakukan analisa uji proksimat, yaitu pengujian kadar air, pengujian kadar abu dan pengujian kadar zat terbang. Hasil pengujian menunjukkan bahwa nilai kalor biobriket dari komposisi tempurung kelapa dengan sabut kelapa adalah sebesar 3708,34 cal/g, sedangkan nilai kalor untuk biobriket komposisi tempurung kelapa dengan sekam padi adalah sebesar 3145 cal/g. Dari penelitian di atas, dapat ditarik kesimpulan, bahwa variasi komposisi bahan baku dalam pembuatan briket antara tempurung dengan sabut kelapa dan tempurung kelapa dengan sekam padi, memberikan pengaruh terhadap kadar air, kadar abu, kadar zat terbang dan nilai kalor.
The Teaching of Literary Theory through the Shock of Not Understanding the Text. Crime and Punishment
Authors:   Columbia University, Meerson Olga A.
Published: March 2023

This article presents an exercise in the close reading of two adjacent small chapters in Crime and Punishment — 3 and 4, in Part One of the Novel — Raskolnikov’s Mother’s letter and her son’s reaction to it, respectively. The exercise consists of two activities — homework preparation and its discussion in the classroom. The homework consists of a series of questions as reading guidelines, training the students to look for evidence in the text. These guidelines aim at alerting the students to the speaker’s and the listener’s respective attitudes to what matters to each about the topic of their conversation or, no less importantly, about what they deliberately omit: 1. the use of pronouns — personal as well as demonstrative and adverbial: Pointing to what matters instead of naming it, pronouns allow for a shift of referents. This, paradoxically, makes them more “loaded,” entailing a “naked,” shockingly direct, demonstration of attitude clashes. This requires a semiotic approach regarding deixis. 2. ostranenie/defamiliarization of these attitudes: the students initially presume that they understand what ails or concerns the characters but then discover how different their actual sore spots are — not merely from those presumed by the reader but from one another. Here, Russian Formalist Theory may come handy. 3. polyphony in Bakhtin’s sense — when the discourse offered by one speaker or character becomes re-accentuated by another, in both the way they listen and register the speech and the way they respond to it. Thus the theoretic approaches the students will use will be deliberately eclectic — whatever fits the purpose for the task at hand. The purpose of this exercise is two-fold. On the one hand, it makes theoretical approach relevant. The students begin to apply Literary Theories as instruments for understanding the text, rather than “worshipping” theory as the goal of their exercise in literary studies. On the other hand, it lets close readings counter any ideological reductionism. As the students develop their own interpretive skills, they also build up resistance to brain-washing or pre-digested interpretations, or to any attempted surrogates for their unmediated encounter with the primary text. The skill the students will thus acquire will be free, independent critical thinking. This, in turn, will re-invigorate their sense of Dostoevsky’s relevance, both ethical and aesthetic.
Mikhail Mokeev. Demons: Translating Dostoevsky into the Language of Modernity
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Kasatkina Tatiana A.
Published: March 2023

The article discusses the staging of Fedor Dostoevsky’s novel Demons in Brusnikin workshop (Directors: Dmitry Brusnikin, Mikhail Mokeev, Mikhail Rakhlin). The play, staged by the final year of the Moscow Art Theater School in 2013, was played until the end of May 2021, and after that was not removed from the repertoire, but replaced by the play “Demons. The Night.” The performance is staged in the style of the New Russian Drama, which includes a large amount of improvisation, the involvement of the audience in the course of the performance, the fact of rethinking and refining key points right during the performance. Essentially, the production itself is existential, and requires from the actors to experience situations that reveal them to themselves in a new form and quality during each performance. In the article we will talk about the philosophy involved in the symbolic level of the performance.
How and Why Read Dostoevsky?
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Kasatkina Tatiana A.
Published: March 2023

To some people Dostoevsky opens the real dimension of their human being, allows them to grow up to sanctity, while others feel that the writer casts them into depression, violates their balance, because in order to reach one’s real dimension transitional boundaries should be destroyed and ontologically delusive anchorages should be left, even when they permit to act effectively on a certain level of reality for a short period of time. Dostoevsky is necessary for those who constantly see the perspective of their own death, and not for those who try by all means to shield themselves from it, even when death is drawing nearer. He is necessary for those who look for the sense of experience in every circumstance of life, for those who understood the difference between the aims of life and the circumstances in which it is lived (comfort or misery, social inclusion or exclusion, etc.). Dostoevsky’s greatest gift to those who can and want to accept it is the idea that got into him after the unfulfilled execution: the main goal for people on earth is to remain human in every circumstance, constantly becoming a bit more human, overcoming obstacles to this both inside and outside the self.
About the Book by Robin Feuer Miller Dostoevsky’s Unfinished Journey
Authors:   Novgorod State University, Podosokorsky Nikolay N.
Published: March 2023

The review is dedicated to the monography by Robin Feuer Miller, professor of Russian Literature and Comparative Literature at Brandeis University, Dostoevsky’s Unfinished Journey, translated into Russian in 2022. Miller’s book is written in the spirit of comparative studies and collects different essays about literary influences and intertextuality in Dostoevsky’s work.
The Gnostic Myth in Dostoevsky’s Story The Landlady
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Magaril-Il’iaeva Tatiana G.
Published: March 2023

The article demonstrates how the gnostic paradigm, in which Dostoevsky formed the problems of his early work, is present in the story The Landlady. It is proven that the central plot of the story (Ordynov’s meeting with Katerina and Murin) is based on the writer’s reinterpretation of the metaphorical plot of “The Hymn of the Pearl,” a parable included in the apocryphal acts by the Apostle Thomas. The parable metaphorically recounts the journey of a spiritual man (pneumatic) in a world of matter created and controlled by the Demiurge. This type of person contains the spirit, a particle of the true divine world of the Pleroma. Once in the world of matter, “eating its food,” the spirit is intoxicated and forgets about its true origin. The task of the spiritual man, according to the parable, is to remember that his true home is the Pleroma, and to return to it he must free the Pearl (the divine soul), seized by the serpent (the Demiurge, the ruler of the matter). According to researchers, the imagery of the parable had a great influence on mystical philosophy and art, which flourished, in particular, at the turn of the 18th and 19th centuries. Dostoevsky places the sacred history, presented in myth as in its ideal embodiment, in the reality visible to him, where people are cut off from one another, where passion dominates “unchosen love,” and where the connection with the true Father is lost. Even those who have been given the opportunity to see more than the rest find themselves, at this stage of Dostoevsky’s comprehension of the mystery of man, not strong enough to defeat the serpent.
“One Must Tell the Truth:” Fyodor Dostoevsky and His Contemporaries in the Debate about the Results of the Crimean Campaign
Authors:   State Institute for Art Studies, Saraskina Liudmila I.
Published: March 2023

The paper discusses F.M. Dostoevsky’s attitude towards the Crimean military campaign (1853–1856) and his understanding of the deep meaning of the armed conflict between Russia and the alliance which included the British, French, and Ottoman Empires, as well as the Kingdom of Sardinia. It is argued that F.M. Dostoevsky may be called a “child of the Crimean campaign,” even though he did not participate in it personally, as he remained, all through those months, first a convict and then an exile. However, it was the Crimean campaign that stimulated him to ponder about Russia’s position in the world and about Russia’s geopolitical interests. The Crimean campaign was also well “remembered” by many characters in F.M. Dostoevsky’s novels. The central theme of the paper is the destiny of the three poems that Dostoevsky wrote during his exile in the town of Semipalatinsk. In those poems, the author pointedly presented his evaluation of the events which formed and defined the basis of his worldview. It is sometimes claimed that the main purpose of writing those poems was just pragmatic, allegedly caused by the plight of the author and his desperate desire to come back to literature at any cost. In this paper, this claim is refuted. Especially emphasized is F.M. Dostoevsky’s later avowal that at the very time of the military confrontation he, even though a convict, wished Russia’s victory and not Russia’s defeat. Next, the paper analyses the utterances about the Crimean war by some like-minded contemporaries of F.M. Dostoevsky (the poets F.M. Tyutchev and A.N. Maykov, the historian N.Ya. Danilevsky) as compared with positions of intellectuals and politicians in Europe. F.M. Dostoevsky rejects the assertion that Russia suffered a humiliating defeat in the Crimean war, an assertion that was firmly rooted in the public consciousness and, for many years, taken almost as a universally recognized truth.
FOREIGN PÓLICY OF POST-REVOLUTIONARY IRAN: EXPEDIENCY AT THE CROSSROAD OF SUPRA-NATIONALISM AND SOVEREIGNTY
Authors: Khelghat-Doost Hamoon
Published: March 2023

Following the Iranian Revolution of 1979 and the subsequent formation of the Islamic Republic, the Islamization of Iran’s foreign policy has arguably become the newly established state’s primary agenda on the international arena. In accordance with Islamic thoughts on international relations, the Islamic Republic’s foreign policy was constructed on the concept of Islamic supra-nationalism - which places its emphasis on the unity of the global Muslim community (Ummah). Arguably, this supra-nationalist doctrine is incompatible with the current political world order which is based on the concept of the Westphalian nation-state. This incompatibility exists on three levels; firstly, Islam places its emphasis on ideological boundaries rather than political borders and therefore rejects the idea of nationalist states. Secondly, Islam denies current sources of legitimacy with regard to international laws and regulations, and finally, Islam calls for the elimination of cultural, ethnic and geographical boundaries among Muslims in order to unite Muslim communities in a new power bloc within the current political world order. This paper firstly identifies the differences between Islamic supra-nationalism and the doctrine of Westphalian sovereignty. Secondly, by emphasizing on the concept of maslahat (expediency) and by using several examples; this paper also provides explanations on how the foreign policy of Iran decides which path to take at the crossroad of supra-nationalism and sovereignty.
Rewritable Creatures. Correspondence between Daniel Aschwanden, Vera Sebert and Lucie Strecker on Mimesis and Hybridity in Choreography
Authors: Lucie Strecker  , Vera Sebert
Published: March 2023

Lucie Strecker (Angewandte Performance Laboratory and Department of Art and Communication Practices) reveals the artistic working process preceding a production with the contribution "Rewritable Creatures", reflecting on mimesis and hybridity in choreography through an exchange of letters with the late performer Daniel Aschwanden (Angewandte Performance Laboratory and Department of Art and Communication Practices) and the author Vera Sebert. As the three letter-writers search, speculate and ask each other questions, the text becomes a written performance, revealing an immediate, polyphonic approach to the subject that allows readers to become part of the performance. In this way, processes of hybridisation become manifest in writing. The performance, however, cannot be completed; Aschwanden’s sudden death interrupts the text, turning the contribution, in a sense, into a memorial to an artist, friend, and colleague and the readers into witnesses.
Targeting Cancer Cell Signaling Using Precision Oncology Towards a Holistic Approach to Cancer Therapeutics
Authors: Kumar Manish
Published: March 2023

The mutational changes occurring in the regulatory genes responsible for
the maintenance of optimal cell growth and proliferation gradually lead
to cancer progression and metastasis. Furthermore, patients with the
same cancer types often respond differently to different cancer
therapies, indicating the need for a patient-specific treatment regimen
for the disease. Precision 34 oncology is the new field of cancer
research that relies on genetic profiling of individual tumors  to
identify targetable alterations for custom-tailored personalized
treatment of the disease. It is to rely upon the genomic study of cancer
cells to get a clear picture of the prognosis and pathways involved in
disease progression and to look for the means to selectively target them
for a cure. This article intends to briefly explain the foundations and
frontiers of precision oncology in the context of technological advances
being made in this direction to assess its scope and importance in the
realization of a proper cure for cancer.
Performance characteristics of basophil activations tests for diagnosing penicillin allergy: a meta-analysis
Authors: Bennett Miriam , Wu Jiakai , Mathioudakis Alexander G. , Tontini Chiara , Thomas Iason , Simpson Angela
Published: March 2023

Approximately 10% of the global population identify themselves as
penicillin allergic, yet 90% are not truly allergic and could safely
tolerate penicillin. There is no simple way to identify these people.
Current in vitro diagnostics include specific immunoglobulin E
(with a sensitivity of 19% and specificity of 97%) and basophil
activation testing (BAT) with undefined sensitivity and specificity.
PubMed and EMBASE searched from inception to 03/05/2022 for original
studies evaluating the performance characteristics of basophil
activation test for penicillin allergy in adults. Study selection, data
extraction, risk of bias (RoB) assessment with QUADAS-2 tool and
certainty assessment with GRADE methodology were performed
independently, in duplicate. Meta-analysis was performed using Reitsma
methodology. Twenty-two studies fulfilled the inclusion criteria. Twelve
used the same positive threshold giving a summary point sensitivity 51%
(95% CI, 46%-56%) and specificity 89% (95% CI, 85%-93%).
Significant RoB identified, due to patient selection. GRADE certainty of
evidence rated sensitivity “very low” due to imprecision and
specificity as “low”. Use of 1000 basophils per test did not improve
performance above 500 basophils. BAT has improved sensitivity but lower
specificity over other in vitro diagnostics in penicillin
allergy. BAT methods need to be standardised to limit heterogeneity in
results.
Extreme values of solution of Caputo-Hadamard uncertain fractional differential equation and applications
Authors: Liu Hanjie , Zhu Yuanguo , He Liu
Published: March 2023

Uncertain fractional differential equation (UFDE) is an useful tool for
studying complex systems in uncertain environments. In this paper, we
study the extreme value theorems of the solution to Caputo-Hadamard
UFDEs and applications. A numerical algorithm for solving the numerical
solution of a nonlinear Caputo-Hadamard UFDE is presented, the
feasibility of the numerical algorithm is validated by numerical
experiments. The extreme value theorems are applied to the financial
markets, and the pricing formulas of the American option based on the
new uncertain stock model are given. Considering the properties of the
American option pricing, the algorithms for computing the expected value
of the extreme values based on the Simpson’s rule are designed. Finally,
the price fluctuation of the American option is illustrated by numerical
experiments.
The linearized Poisson-Nernst-Planck system as heat flow on the interval under non-local boundary conditions
Authors: Wolansky Gershon
Published: March 2023

The linearized of the Poisson-Nernst-Planck (PNP) equation under closed
ends around a neutral state is studied. It is reduced to a damped heat
equation under non-local boundary conditions, which leads to a
stochastic interpretation of the linearized equation as a Brownian
particle which jump and is reflected, at Poisson distributed time, to
one of the end points of the channel, with a probability which is
proportional to its distance from this end point. An explicit expansion
of the heat kernel reveals the eigenvalues and eigenstates of both the
PNP equation and its adjoint. For this, we take advantage of the
representation of the resulvent operator and recover the heat kernel by
applying the inverse Laplace transform.
Debottlenecking and reformulating feed media for improved CHO cell growth and titer by data-driven and model-guided analyses
Authors: Park Seo-Young , Choi Dong-Hyuk , Song Jinsung , Park Uiseon , Cho Hyeran , Hong Bee Hak , Silberberg Yaron R. , Lee Dong-Yup
Published: March 2023

Designing and selecting cell culture media and their feeding are a key
strategy to maximize culture performance in industrial biopharmaceutical
processes. However, mammalian cells are very sensitive to their culture
environment, requiring specific nutritional needs to grow and produce
high-quality proteins such as antibodies, depending on cell lines and
operational conditions. In this regard, previously we developed
data-driven and in-silico model-guided systematic framework to
investigate the effect of growth media on Chinese hamster ovary (CHO)
cell culture performance, allowing us to design and reformulate basal
media. To expand our exploration for media development research further,
we evaluated two chemically defined feed media, A and B, in ambr15
bioreactor runs using a monoclonal antibody-producing CHO K1 cell line.
We observed a significant impact of feed media on cell growth,
longevity, viability, productivity and toxic metabolites production.
Specifically, concentrated feed A was not sufficient to support
prolonged cell culture and high titer compared to feed B. The framework
systematically characterized the major metabolic bottlenecks in the TCA
cycle and its related amino acid transferase reactions, thereby
identifying key design components, such as asparagine, aspartate, and
glutamate, which are needed for highly productive cell cultures. Based
on our results, we subsequently reformulated the feeds by adjusting the
amounts of those amino acids and successfully validated their
effectiveness in promoting cell growth and/or titer.
Limiting-Efficiency Assessment on Advanced Crystalline Silicon Solar Cells with Auger Ideality Factor and Wafer Thickness Modifications
Authors: Su Qiao , Lin Hao , Wang Genshun , Tang Hanbo , Xue Chaowei , Li Zhenguo , Xu Xixiang , Gao Pingqi
Published: March 2023

With the improvement of surface passivation, bulk recombination is
becoming an indispensable and decisive factor to assess the limiting
efficiency ( η lim ) of crystalline silicon (c-Si) solar cells. In
simultaneous consideration of surface and bulk recombination, a modified
model of η lim   evaluation is developed. Surface recombination is
directly depicted with contact selectivity while bulk recombination is
revised on the aspects of ideality factor and wafer thickness. The η lim
of cutting-edge photovoltaic technologies, double-side tunneling-oxide
passivating contact (TOPCon) and silicon heterojunction (SHJ) solar
cells, are numerically simulated using the new model as 28.73% and
29.00%, respectively. Hybrid solar cells consisting of n-type TOPCon
contact and p-type SHJ contact can approach an η lim as high as 29.18%
at the optimal wafer thickness ( W opt ) of 103 μm . Our results are
instructive in accurately assessing efficiency potential and accordingly
optimizing design strategies of c-Si solar cells.
Dynamic Stress and Failure Characteristics around an Elliptical Cavity Subjected to Impact Loading
Authors: Zhao Rui , Tao Ming , Zhao Huatao , Cao Wenzhuo , Wu Chengqing
Published: March 2023

Based on complex conformal mapping and Duhamel’s integral method the
steady and transient dynamic stress distribution around an elliptical
cavity subjected to plane P-wave was obtained. The influence of incident
angle(θ0), axial ratio(k) and normalized wave length (t0) on the dynamic
stress concentration factor (DSCF) was evaluated. Further, the finite
element method (FEM) software LS-DYNA was utilized to validate the
analytical solution. The results indicated that the maximum compression
DSCF increased with θ0, except θ0=0, and decreased with k. When θ0=0 the
maximum tensile DSCF increase with the decrease of k. The position of
maximum compression and tensile DSCF varied with incident θ0. Under the
transient incident condition DSCF was affected by normalized wave length
t0, with the increasing of t0 the DSCF gone up then down finally gone
closed to the static stress concentration factor. Further, the stress
state around the elliptical cavity under transient impact loading was
compared with the experimental results of elastic stress distribution
and plastic failure and got a good agreement, and possible dynamic
failure modes of elliptical cavity were discussed.
Hypogonadism due to pituitary macroadenoma with inflammatory bowel disease and hemolytic anemia in a 22 years old Sudanese patient
Authors: AHMED FADI , DIAB DANIA , FADLALLAH KHALID , ALTEIB MOGAHID , SAIFALDEEN MONZER , MOHAMMED AHMED , BABIKER Mohammed , ELDAI YASIR , MAHMOOD FAYHAA , BALLA SAMER
Published: March 2023

We report a case of 22 years old male who presented with
headache,bodyaches,cough,fever,vomiting,and diarrhea for short duration.
investigations showed features of hypogonadism due to pituitary
macroadenoma.He had long history of recurrent attacks of anemia and
diarrhea, his anemia was due to MAHA. serial endoscopies and
colonoscopies showed features of IBD.
Lonicerin alleviates ovalbumin-induced asthma of mice via inhibiting EZH2/NF-κB signaling pathway
Authors: Wang Yan , Dai Rui , Xiang Yun , Fang Rui , Zheng Hai-Han , Qing-Song *
Published: March 2023

Asthma is the most common chronic disease in the respiratory system of
children caused by abnormal immunity that responses to common antigens.
Lonicerin exerts anti-inflammatory activity in other inflammatory models
through targeting enhancer of zeste homolog 2 (EZH2) that is related to
asthma. We sought to explore the role and mechanism of lonicerin in
regulating allergic airway inflammation. Mice were intraperitoneally
injected 10 μg ovalbumin (OVA) on postnatal day 5 (P5) and P10, and then
inhaled 3% aerosolized OVA for 10 min every day on P18-20, to establish
asthmatic mice model. Lonicerin (10 or 30 mg/kg) was given to mice by
intragastric administration on P16-P20. Notably, the administration of
lonicerin amended infiltration of inflammatory cells and mucus
hypersecretion. OVA-specific IgE level, inflammatory cell count and
inflammatory cytokines in asthmatic mice were reduced after lonicerin
treatment. Moreover, it suppressed the activity of EZH2 and activation
of nuclear factor-kappa B (NF-ĸB) as evidenced by decreasing
tri-methylation of histone H3 at lysine 27 (H3K27me3) and reducing
nuclear translocation of NF-κB p65. In a word, Lonicerin may attenuate
asthma by inhibiting EZH2/NF-κB signaling pathway.
PREVALENCE OF YELLOW FEVER VIRUS AMONG LASSA FEVER PCR NEGATIVE FEBRILLE PATIENTS IN NIGERIA
Authors: Nicholas Aderinto , Abdulbasit Abdulrahman , Toluwani Ajayi D. , T Adeyemo Abolaji , Adeyemi Adeyemo T. , Abdulwasiu Hassan O. , Opeyemi Abdulbasit , Elizabeth Oladipo
Published: March 2023

Background Yellow fever is a viral illness caused by an RNA
virus from the Flavivirus genus, which is transmitted between humans and
Aedes aegypti mosquitoes. Although the virus often spreads through a
specific transmission method (Sylvatic Cycle), it can also cause a
generally brief illness in infected individuals. Methodology
The study was designed as a cross-sectional investigation that analyzed
stored Lassa fever PCR negative febrile samples. Randomly, 40 samples
were selected and enrolled in the study. The RT-PCR technique was
employed to convert the RNA virus to a complementary RNA and
subsequently amplify it. The Quagen Analysis was used to analyze the
results of the FAM (yellow fever-specific RNA) and the JOE (internal
control). Results After analyzing the samples, the results
revealed that none of the studied samples were positive for the Yellow
Fever virus. Conclusion The study concluded that there was no
evidence of yellow fever transmission among the population in Owo,
Nigeria. The findings suggest that the virus’s spread has been
significantly controlled through vaccination programs in the community.
The better the relationship the more coordinated cooperation in dating couples? An Evidence from EEG Hyperscanning
Authors: Wang Fei , Gong Xiao , Wang Xiu , Zhang Xinyi , Hu Shiang , Hou Juan
Published: March 2023

Existing research has found that individuals with higher relationship
quality in intimate relationships tend to exhibit higher levels of tacit
understanding and better interpersonal coordination in social
interactions. However, the cognitive neural mechanisms between intimate
relationship quality and interpersonal coordination are unclear. We thus
argued that interpersonal neural synchronization during interpersonal
interactions is an important mediator of intimacy quality and
interpersonal coordination. To test this hypothesis, interpersonal
neural synchrony and interpersonal coordination were measured in
heterosexual dating couples during the completion of a jigsaw puzzle
interaction task using an EEG-based hyperscanning technique. A total of
33 couples’ data were included in the analysis. The results showed that
β-band synchronization in the left sensorimotor cortex of both members
of a romantic couple fully mediated the relationship between intimacy
quality and interpersonal coordination during the jigsaw puzzle task. In
addition, we found that intimacy quality significantly predicted
interpersonal neural synchrony in a jigsaw puzzle task with interaction
but not in a jigsaw puzzle task without interaction. These findings
support the idea that intimacy is a result of interindividual
interactions and that interpersonal neural synchronization during
interactions plays an important role in relationship quality and
interpersonal coordination.
A Harmonic Model of MMC Based on Nearest-Level Modulation With the Equidistant Controlled Firing Scheme
Authors: Chen Xiaowen , Jiao Zaibin
Published: March 2023

With the rapid development of flexible DC transmission systems, the
application of modular multilevel converter MMC is becoming increasingly
widespread. Meanwhile, the nearest-level modulation is most applied.
This paper establishes a simple and efficient harmonic model of MMC
based on nearest-level modulation with the equidistant controlled firing
scheme. First, based on the analysis of the working principle of MMC and
the modulation principle, the Fourier decomposition of the stair wave is
obtained. Then, according to the equivalent circuit diagram of MMC, the
stair wave is exactly the differential-mode voltage. Moreover, the
amplitude and phase of each differential-mode voltage harmonic content
are obtained. So far, MMC can be regarded as a harmonic voltage source.
Finally, simulations were performed on PSCAD to verify the accuracy of
the MMC harmonic model proposed in this paper. Furthermore, the MMC
harmonic model under the equidistant controlled firing scheme and
real-time trigger control were also compared. The final results show
that the model proposed in the paper can accurately reflect the harmonic
characteristics of MMC in the existing power system after considering
the equally-spaced trigger control.
How to diagnose H63D Syndrome Type-2
Authors: Diamandis Dr. Carolina , Shirazi Ali , Honda Riku , Rocha Fabio , Bartels Alexander
Published: March 2023

H63D Syndrome Type-2 is a complex genetic disorder with diverse manifestations, including erratic iron metabolism, micro-inflammatory cascades, neuropsychiatric issues, organ damage, and other rare multi-faceted symptoms. A comprehensive understanding of the pathophysiology underlying this condition is essential for accurate diagnosis, appropriate management, and the development of targeted therapeutic approaches. Healthcare professionals should adopt a multidisciplinary approach to patient care and emphasize the importance of early detection, intervention, and patient education in the management of H63D Syndrome Type-2. Future research should focus on gene editing technologies and novel therapies to address the underlying genetic mutation and the diverse symptoms associated with the disorder.
Exploring the Success Factor Of Digital Marketing: A case study of Private Healthcare Organization in an Emerging Economy
Authors: Mallick Sidra Urooj
Published: March 2023

Abstract

The purpose of this study is to assess the potential of social media platforms to build a successful marketing campaign for the private health-care industry. This will be accomplished by studying the current trends, audiences, and marketing tactics that are applied to these channels. In addition, the research will make a contribution to this understanding by investigating the efficacy of various types of marketing strategies that are used in the private health-care industry, such as influencer marketing, content marketing, and social media advertising, and how these strategies can be leveraged to create marketing strategies that are more effective. This research project will also focus on identifying any bottlenecks that could be hindering the utilisation of these channels and providing solutions to improve their effectiveness in the marketing mix. This will be done as part of the overall goal of improving the effectiveness of the marketing mix. At the end of the day, the purpose of this research is to develop an understanding of how social media channels can be utilised successfully as an important instrument in marketing for the health-care industry.
The Optimization of working parameters to improve the quality of plastics in an injection molding process
Authors: Iqbal Muhammad Iqbal Asif , Amjad Muhammad
Published: March 2023

Improvement is required in any industry to increase the productivity by reducing the defects rate and remove the overall waste produced during manufacturing process. In this research paper, the working parameters are optimised that are responsible for process variation. A plastics manufacturing company, the major problems were flow marks and air bubbles appeared on the surface of mould part a car side mirror plastic cover. Because of these problems, the overall production of company was decreasing that resulted in customer dissatisfaction and company could not achieve its daily production target. The responsible working parameters for process variation are found to be injection pressure, melting temperature along with viscosity and flow rate of molten material during injection moulding process.  The injection speed and screw speed are also considered. The analysis of variance (ANOVA) test was conducted to find most critical working parameters. It is identified that response surface methodology (RSM) can be used to optimise the working parameters to improve the quality of moulded part that will increase process efficiency by 50%. The data was collected from four machines to find which machine is causing more problems that is found to be Tederic 450 tone machine. This machine has more problems as compared to other machines. Acrylonitrile Butadiene Styrene (ABS) material is used for the production of car side mirror plastic cover. The Rejection of this moulded part was counted 35% of total rejection. After optimization, the rejection is reduced to 16% is recorded which is significant improvement.
Understanding the role of automation in society
Authors: Touseef Muhammad , Siddiqui Saira , Farah Nabeela
Published: March 2023

Automation is the procedure of operating technology to manage and operate tasks, machines, and processes without the need for human input. It employs control systems and advanced technology to enable self-sufficiency in the functioning these systems.We have conducted this study to examine the effects and ramifications of automation on contemporary society, considering its impact on productivity, employment, morality, and economic and social development. It provides an overview of the current state of automation and its potential impact on society. Our study has found that automation has positive and negative consequences for society, including a decline in the job market and a change in the skills set for employment. It was a comprehensive qualitative study that included a literature review, 16 online interviews with experts from 16 countries, and online surveys. We categorized the findings by analyzing the data using thematic analysis. Our results suggest that there should be laws and regulations on the use of automation in society to minimize its adverse impacts on society. This study suggests that automation should improve the quality of life and create more opportunities for people in the market. This research provides insights into the implications of automation on society and its potential to improve efficiency, labour, ethics, and economic and social progress. This research will inform policymakers and other stakeholders about automation's potential benefits and risks.
Quality optimization of OSPFV3 and EIGRP for IPV4 in hierarchical network environment using GNS3 tool
Authors: Brohi Allah Bachayo , Riffat Saher  , Shaikh Asad Ali
Published: March 2023

In network world, due to shortage of IP addresses in version 4, a new version of IP address, namely IPv6, has come into play, but due to non-exchange ability between IPv4 and IPv6, different routing protocol is come to play for IPv6 that is RIPng, OSPFv3 and EIGRP for IPv6 in the place of RIP, OSPFv2 and EIGRP in IPv4 environment. Transmission of data is based on the routing protocol which selects the best routes in network world. Two types of interior routing protocol which selects the best routes in network world that is distance vector and link state. In this research we compare two types of routing protocol are chosen as the simulation base that is OSPFv3 (Link state) and EIGRP IPv6 (Distance Vector) in terms of convergence and router CPU usage. These routing protocols are mostly used in network as well as internet. In this project, we are going to use GNS3 to simulate and compare OSPF and EIGRPv6 with authentication and without authentication in large hierarchical network using ipv4 and ipv6 environment. On top of everything, as a second step GNS3 simulator installed. Familiarity with GNS3 is essential to achieve this research study. As a second step, a certain hierarchical routing scheme scenarios will be created. Secondly, OSPFv3 and EIGRP IPv6 without authentication implemented and configured to get the required results in terms of CPU processing power and convergence time.  Later, OSPFv3 and EIGRP IPv6 with authentication  implemented and configured to get results for a comparison in terms of resources usage and convergence. As a final stage overall results of the research study compared to analyze the research parameters which are with and without authentication on both routing protocols. At the end of this research study, the result is drawn and presented in the thesis and a final comparative analysis presented in tabular format. In this Research study compare two parameters, CPU utilization and Processing power with and without authentication. We found that OSPFv3 uses less power as compared to EIGRP for IPv6 without authentication in hierarchal environment, but it takes more time to converge and with authentication it is also found that it ospfv3 uses less power as compared to EIGRP for IPv6 while EIGPR for IPv6 is faster than OSPFv3.
Regionalne zróżnicowanie pogłowia zwierząt w Polsce
Authors: Grontkowska Anna
Published: March 2023

Celem opracowania jest określenie zmian w pogłowiu bydła i trzody chlewnej w ujęciu wojewódzkim w Polsce. W opracowaniu wykorzystano publikowane dane z trzech powszechnych spisów rolnych (PSR) przeprowadzonych w latach 2002, 2010 i 2020. Z przeprowadzonych badań wynika, że w latach 2010–2020 pogłowie bydła ogółem zwiększyło się, szczególnie w województwach wielkopolskim, mazowieckim i podlaskim, przy jednoczesnym jego zmniejszeniu w województwach podkarpackim, małopolskim i lubelskim. Pogłowie trzody chlewnej z kolei zmniejszyło się bardzo wyraźnie, a zmiany w ujęciu regionalnym są trudne do jednoznacznej interpretacji. Wynika to głównie z ograniczeń w produkcji żywca wieprzowego spowodowanych występowaniem wirusa afrykańskiego pomoru świń, szczególnie we wschodniej Polsce.
The impact of war in Ukraine on the inbound tourism in Lithuania
Authors: Variakojienë Jolita , Achonen Irena
Published: March 2023

The objective of this paper is to examine the impact of the war in Ukraine on the inbound tour operators. The hypothesis that war in Ukraine has a significant impact on Lithuanian inbound tour operators was tested using a quantitative research method. To do so, the data was collected through an online survey, targeting Lithuanian inbound tour operators providing ground services for international tourists in Lithuania. The moment of the survey (2022, April) provided opportunity to examine the effect of war in Ukraine on inbound tourism. The results show that the war has a serious negative impact on tourism arrivals to Lithuania. The study found that the number of bookings has decreased heavily, what also means decrease in tourism revenues. The main cancellation reasons that were mentioned are military conflict in Ukraine and unsafe situation. Biggest number of cancellations arrived from Germany, United States and France. Tourism products with the greatest impact are cultural, business tourism and weekend trips. Our study is, to the best our knowledge, the first to examine the impact of the war in Ukraine on the inbound tour operators. Results from the study hold potential for better understanding how war and political instability influence business performance.
Marketing analysis of diversification of the factors determining the market conditions of the space tourism market
Authors: Vovchanska Olha , Ivanova Liliya
Published: March 2023

The study is dedicated to the marketing analysis of the diversification of the factors affecting the formation and development of the market conditions of the space tourism market. The article summarizes scientific approaches to the definition of space tourism, systematizes the features of the formation and development of the global space tourism market, and analyses the indicators of the development of the space tourism market in the leading spacefaring countries of the world. The actual determinants of the development of the world market of space tourism have been identified, as well as main motivational factors of space tourists. The main endogenous and exogenous factors for the development of the space tourism market were investigated. Attention was focused on the fact that the modern economic mechanism for the development of the space tourism market is based on the concept of marketing with its main elements adapted. Marketing directions for the popularization of tourist space flights were researched. It is concluded that the space tourism market has a huge potential. Space travel has become a reality, and in the foreseeable future space tourism will become massive, while the industry of space experiences will develop at an accelerated pace, stimulating the emergence of other lucrative sub-markets.
Catalytic performance of desilicated HZSM-12 for benzylation reaction of benzene with benzyl alcohol
Authors: Akyalcin Sema , Akyalcin Levent , Bjørgen Morten
Published: March 2023

The catalytic production of diphenylmethane from the reaction of benzene with benzyl alcohol was investigated using HZSM-12 and desilicated HZSM-12 that was obtained by treating ZSM-12 with 0.2M NaOH solution at 85 ?C for 60 min. The untreated and alkaline treated ZSM-12 zeolites were characterized by X-ray diffraction, nitrogen adsorption/desorption isotherms, scanning electron microscopy, inductively coupled plasma optical emission spectrometry, and temperature-programmed desorption of ammonia. The desilicated HZSM-12 showed promising catalytic performance with benzyl alcohol conversion of 100% and the selectivity to diphenylmethane of 74% and 87% in 4 h and 8 h reaction time, respectively. The reaction parameters affecting benzyl alcohol conversion and product distribution were also presented. The activities of fresh and regenerated catalysts were compared, and characterization results indicated that the occluded organic molecules decreased the number of acidic sites of the catalyst after the reaction and regeneration.
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings
Authors: Mastracci Teresa L. , Apte Minoti , Amundadottir Laufey T. , Alvarsson Alexandra , Artandi Steven , Bellin Melena D. , Bernal-Mizrachi Ernesto , Caicedo Alejandro , Campbell-Thompson Martha , Cruz-Monserrate Zobeida , El Ouaamari Abdelfattah , Gaulton Kyle J. , Geisz Andrea , Goodarzi Mark O. , Hara Manami , Hull-Meichle Rebecca L. , Kleger Alexander , Klein Alison P. , Kopp Janel L. , Kulkarni Rohit N. , Muzumdar Mandar D. , Naren Anjaparavanda P. , Oakes Scott A. , Olesen Søren S. , Phelps Edward A. , Powers Alvin C. , Stabler Cherie L. , Tirkes Temel , Whitcomb David C. , Yadav Dhiraj , Yong Jing , Zaghloul Norann A. , Pandol Stephen J. , Sander Maike
Published: March 2023

The Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases workshop was a 1.5-day scientific conference at the National Institutes of Health (Bethesda, MD) that engaged clinical and basic science investigators interested in diseases of the pancreas. This report provides a summary of the proceedings from the workshop. The goals of the workshop were to forge connections and identify gaps in knowledge that could guide future research directions. Presentations were segregated into six major theme areas, including 1) pancreas anatomy and physiology, 2) diabetes in the setting of exocrine disease, 3) metabolic influences on the exocrine pancreas, 4) genetic drivers of pancreatic diseases, 5) tools for integrated pancreatic analysis, and 6) implications of exocrine–endocrine cross talk. For each theme, multiple presentations were followed by panel discussions on specific topics relevant to each area of research; these are summarized here. Significantly, the discussions resulted in the identification of research gaps and opportunities for the field to address. In general, it was concluded that as a pancreas research community, we must more thoughtfully integrate our current knowledge of normal physiology as well as the disease mechanisms that underlie endocrine and exocrine disorders so that there is a better understanding of the interplay between these compartments.
Pathway From Type 2 Diabetes Diagnosis to Action: How to Move People Forward
Authors: Boakye Michelle D.S. , Miyamoto Sheridan , Greenwood Deborah , Kraschnewski Jennifer , Van Haitsma Kimberly , Boltz Marie
Published: March 2023

Seven self-care behaviors—healthy coping, healthy eating, being active, taking medication, monitoring, reducing risk, and problem-solving—are recommended for individuals with diabetes to achieve optimal health and quality of life. People newly diagnosed with type 2 diabetes may find it challenging to learn and properly incorporate all of these self-care behaviors into their life. This qualitative study explored the experiences and perceived immediate self-management and psychosocial support needs in individuals newly diagnosed with type 2 diabetes. Data analysis revealed the significant challenges individuals encounter after a type 2 diabetes diagnosis. Five main themes were identified: 1) type 2 diabetes diagnosis competes with other complex life challenges, 2) difficulty in performing behavior modification actions, 3) lack of support, 4) emergence of emotional and psychological issues, and 5) need for planned individualized follow-up support after a type 2 diabetes diagnosis. This study revealed a gap in care after type 2 diabetes diagnosis. Individualized support is needed to assist people in moving successfully from diagnosis to being well equipped with the knowledge and skills necessary to properly manage the condition.