bluuebunny/crossref_metadata_2025 huggingface dataset:
GAMBARAN AKTIVITAS SEDENTARI DAN TINGKAT KECUKUPAN GIZI PADA REMAJA GIZI LEBIH DAN GIZI NORMAL
Authors: Pramudita Sofia Rahma , Nadhiroh Siti Rahayu
Published: July 2018

Sedentary activity is an activity that requires very low energy expenditure, such as sitting or lying down while watching television, playing electronic games, and reading that can cause negative effects on health. One of the negative impactis increasing risk for obesity. The purpose of this study was to describe the nutrition adequacy level and sedentary activity among overweight and normal adolescent. This research was descriptive study with cross-sectional design. Thesample was 70 students of SMPN 3 Gresik which divided into two groups based on their nutritional status, overweight or normal with 35 samples in each group. Data of nutrient intake, sedentary activity, and measurements of height and weight obtained from questionnaires and direct interview with respondents. Research showed that majority of overweight adolescent, had an energy and carbohydrate adequacy levels more than 77% of RDA compared to normaladolescent. Overweight and normal adolescents have a similar protein and fat adequacy level. Overweight adolescents had greater sedentary activity level the normal one. Majority of overweight adolescent have higher adequacy levelof energy, carbohydrate, and sedentary activity than normal adolescent. Reducing consumption of sweet, fatty foods, increase consumption of fruits and vegetables, also increase regular physical activity need to be done by the respondent
HUBUNGAN PRAKTIK PERSONAL HYGIENE PEDAGANG DENGAN KEBERADAAN BAKTERI ESCHERICHIA COLI DALAM JAJANAN KUE LAPIS DI PASAR KEMBANG KOTA SURABAYA
Authors: Nuraya Ardini Debilauralita , Nindya Triska Susila
Published: July 2018

Pathogenic effect of Escherichia coli bacteria could be detrimental to health. The presence of the bacteria makes food unsafe to consumed. Personal hygiene practice of sellers can infl uence the presence of Escherichia coli on food. This cross-sectional study was aimed to analyze the relationship between personal hygiene practice of sellers with the presence of Escherichia coli bacteria on a traditional layer cake. The study involved 29 traditional layer cake sellers inPasar Kembang Surabaya. The data collection was done by using observation sheet and laboratory tests on samples of traditional layer cakes. Data was analyzed using chi-square statistical test. The results of this study showed the majority of sellers washed their hands before handling food (96.6%), fingernails were clean and short (86.2%) and didn’t smoke when handling food (82.8%). All sellers used clean clothes (100%), but talked when handling food (100%), did not wear an apron and tools when handling food (100%). Escherichia coli was found in 44.8% samples. This study showed there was no relationship between personal hygiene practices of sellers with the presence of Escherichia coli bacteria in traditional layer cakes (p > 0.05) in Pasar Kembang.
GAMBARAN AKTIVITAS SEDENTARI DAN TINGKAT KECUKUPAN GIZI PADA REMAJA GIZI LEBIH DAN GIZI NORMAL
Authors: Amir Rizky Arifandy , Adi Annis Catur
Published: July 2018

Sedentary activity is an activity that requires very low energy expenditure, such as sitting or lying down while watching television, playing electronic games, and reading that can cause negative effects on health. One of the negative impactis increasing risk for obesity. The purpose of this study was to describe the nutrition adequacy level and sedentary activity among overweight and normal adolescent. This research was descriptive study with cross-sectional design. Thesample was 70 students of SMPN 3 Gresik which divided into two groups based on their nutritional status, overweight or normal with 35 samples in each group. Data of nutrient intake, sedentary activity, and measurements of height and weight obtained from questionnaires and direct interview with respondents. Research showed that majority of overweight adolescent, had an energy and carbohydrate adequacy levels more than 77% of RDA compared to normaladolescent. Overweight and normal adolescents have a similar protein and fat adequacy level. Overweight adolescents had greater sedentary activity level the normal one. Majority of overweight adolescent have higher adequacy levelof energy, carbohydrate, and sedentary activity than normal adolescent. Reducing consumption of sweet, fatty foods, increase consumption of fruits and vegetables, also increase regular physical activity need to be done by therespondent.
PENERAPAN HACCP DALAM PROSES PRODUKSI MENU DAGING RENDANG DI INFLIGHT CATERING
Authors: Wicaksani Ardanisworo Lintang , Adriyani Retno
Published: July 2018

HACCP is one of the food safety systems which is done by analyzing materials, processes, and food products. HACCP  analysis can be used as an effort to control the quality of the ﬁ nal product in order to meet the requirements of healthy, safe and halal food products. PT X is a catering company for aircraft service users (inﬂ ight catering). This company has implemented HACCP in every food production. This is a descriptive research by observing the process of rendang meat production. The application of HACCP in PT. X is done by controlling temperature and time during production process to prevent microbes growth. From ten application of HACCP according to SNI No. 01-4852-1998 about HACCP there is a point that has not been accordance with SNI monitoring. Monitoring activities are not routinely performed on blast chilling and dishing process. Pieces of coconut milk’s pack fall in to the pan when cooking process because the cutting of coconut milk pack is done on the cooking pan. Other HACCP principles like HACCP team determination, product description, ﬂ ow chart reaction, hazard identiﬁ cation, critical point determination, critical boundary determination of each CCP, corrective action, microbiological veriﬁ cation, and documentation are well implemented.
PENDIDIKAN GIZI MENGGUNAKAN MEDIA BUKU SAKU MENINGKATKAN PENGETAHUAN DAN PRAKTIK KONSUMSI SAYUR DAN BUAH PADA SISWA SEKOLAH DASAR
Authors: Azadirachta Fitria Laras , Sumarmi Sri
Published: July 2018

The average consumption of vegetables and fruits in Indonesia is still low. This condition can cause the emergence of nutritional problems in children. The purpose of this study was to determine the effect of nutritional education using pocketbook to increasing knowledge and practice of vegetables and fruits consumption among elementary students. This research was quasy experiment using pre-test post-test control group design. The sample size was 60 students consisting of 20 students of SDN Kandang Tepus I as control group treated with media leaflet and 40 students of SDN Kandang Tepus II as treatment group given the pocketbook. The result of independent t-test in pre-test of booth groups shows that there was no difference in knowledge (p=0.220) and practice (p=0.091) between the two groups. Independent t-test result on post-test also shows was no difference in knowledge (p=0.421) and practice (p=0.810) between the two groups. The result of paired sample t-test of the treatment group showed the average of pre-test and post-test of knowledge score were 31.50 and 66.25 and the practice were 2.58 and 3.08. There were significant difference of knowledge (p=0.000) and practice (p=0.000) before and after being given pocketbook. Wilcoxon sign rank test in the control group showed that leaflet did not affect knowledge (p=0.052) but affect the practice (p=0.001). It can be concluded that use of pocketbook media influence the knowledge and the respondent practice.
HUBUNGAN KEBIASAAN SARAPAN, TINGKAT KECUKUPAN ENERGI DAN GIZI MAKRO DENGAN STATUS GIZI PADA SISWA PONDOK PESANTREN AL-FATTAH BUDURAN, SIDOARJO
Authors: Rosida Hanik
Published: July 2018

Nutrition plays vital role in the improvement of academic achievement and growth for adolescent. Adolescent have many activity, therefore needs balance nutritional intake. The aimed of this research was analyzed the relation between breakfast habit, macronutrient adequacy level, with nutritional status of adolescent at Al-Fattah Boarding School, Buduran, Sidoarjo. This research was an analytic observational with cross sectional design. The sample of this research was 72 active students of Al- Fattah Boarding School. Breakfast habit and food consumption were collected through food recall 24 hours. Nutritional status determine by Body Mass Index for Age (BAZ). The logistic regression was used to analyze the data. The results showed that majority of respondent has age 13-15 years (75.6%), male (52.8%) and normal nutritional status (52.8%). There was a relation between breakfast habit, carbohydrate and protein adequacy with nutritional status. There was no relation between energy and fat adequacy with nutritional status.
HUBUNGAN ASUPAN ZAT GIZI MAKRO DAN PROFIL LIPID DENGAN KEJADIAN PENYAKIT JANTUNG KORONER PADA PASIEN LANSIA DI RUMAH SAKIT ISLAM JEMURSARI SURABAYA
Authors: Rahma Hadiar Huriyah , Wirjatmadi R. Bambang
Published: July 2018

Coronary Heart Disease (CHD) is a condition where plaque build up inside the coronary artery which could lead to heart attack. One of the factors that affects CHD is food consumption pattern that can increase lipid level so the heart could not get any nutrition optimally. The research was aimed to analyze the relationship between food consumption pattern, and lipid profi le with CHD in elderly patients of Jemursari Islamic General Hospital, Surabaya. The study was a case control design with 20 of case patients who had CHD history and 20 of control patients with dyslipidemia. The analysis used chi-square test for the variables such as carbohydrates and fat intake, meal frequency, total cholesterol level, Low Density Lipoprotein (LDL), and triglycerides level. The result showed that there is relationship between fat intake and CHD (p=0.002; OR=13.500; 95%CI), but there were no relationship between carbohydrates intake (p= 0.105), meal frequency (p=0.451), total cholesterol level (p = 0.237), Low-Density Lipoprotein (LDL) (p = 0.054), and triglycerides level (p=0.341), with CHD in dyslipidemia elderly patient. Elderly patients is expected to maintain their nutrient intake, especially fat intake in order to reduce the chance of CHD.
Exploring Attachment and Spirituality among Christians in China
Authors: Xu Honghong , Pak Jenny , Tu Ruina , Schuberg Mary
Published: July 2018

As research on attachment has exploded, theories and studies on attachment and spirituality also flourished in the west. In contrast, similar researches are scarce in China. Are the attachment theories and measurements applicable universally? Are there any links between parental attachment and God attachment? The present study used mixed methods to examine these questions. First, 355 Christians from Mainland China finished the Relationship Structures Questionnaire (ECR-RS), Attachment to God Inventory, God Image Scales, and Chinese Personality Assessment Inventory-2. Next, a sample of 11 participants were purposefully selected for face-to-face interviews to provide an in-depth understanding of the phenomenon through their life stories and spiritual experiences. Survey results showed significant correlations between parental attachment and spirituality and supported the correspondence theory. Additionally, the higher scores on traditional cultural personality traits correlated with higher scores on insecure attachment. Analysis of themes across 11 cases further revealed patterns between secure/insecure parental attachment and God attachment. Application of western attachment scales in the context of Chinese characteristic parenting styles are discussed.
Effects of Light Intensity on Spatial Visualization
Ability

Authors: Katsioloudis Petros J. , Jones Mildred
Published: July 2018

A plethora of technological advances have happened since artificial illumination
was developed by Thomas Edison. Like technology has had an effect in many areas in the
modern civilization it also made a difference in the classroom. Nowadays, students can
have instruction in classrooms with no external windows, even during gloomy winter or
rainy days, and virtually during any hour of the day. Several lightning devices are
being used, ranging from energy efficient LEDs to fluorescent lighting. Some forms of
lighting methods have been found to be inappropriate for prolonged exposure to the human
eye such as various gas-discharge lamps that create poorer color rendering due to the
yellow light. A large number of research studies have focused on topics such as the
effect of light on intensity to oral reading proficiency, its effect on stress levels,
and the effect it may have on autistic children. However, a small number of studies was
found related to the optimal levels of light intensity related to successful student
learning regarding spatial visualization ability. The purpose of the current study is to
identify whether light intensity can increase or decrease spatial ability performance
for engineering technology students.
Professional Advisers in Engineering and Technology Undergraduate
Programs: Opportunities and Challenges

Authors: Mosher Gretchen A.
Published: July 2018

The basis of high quality academic advising is a strong relationship between the
student and the adviser. Historically, these relationships have been cultivated between
faculty advisers and students. Increasingly, the “faculty-only” model is declining, as
institutions have chosen to hire non-faculty staff to serve the role of academic
advisers. These “professional advisers” focus solely on advising, with limited research,
teaching, and governance duties. This article summarizes the research on the use of
professional advisers as compared with faculty advisers, and outlines challenges
inherent to the professional adviser model in an engineering and technology department
at a research-intensive land grant institution. Information on the use of professional
advisers in an engineering and technology department may be useful to other engineering
and technology-oriented departments, specifically those managing large enrollment
increases. Factors considered in measuring advising effectiveness for professional and
faculty advisers will also be discussed. As administrators in engineering and technology
departments add to the list of tasks required for faculty, the use of professional
advisers shifts the faculty mentoring focus toward disciplinary and career pursuits,
roles faculty have indicated they are comfortable assuming.
Pyramid of Structure, Pengungkapan Transaksi Pihak Berelasi, dan Tata Kelola Perusahan : Indikasi Ekspropriasi
Authors: Malawat Fadli Fendi , Sutrisno Sutrisno , Subekti Imam
Published: July 2018

The objective of this study is to analyze the effect of company’s ownership through pyramid structure, and related party transaction disclousure, on expropriation practices, with corporate governance as moderating variable. Analytical technique used is hierarchical  regression  analysis for testing hypotheses developed in this study. Research population is a manufacturing company listed in Indonesia Stock Exchange (IDX) during years 2014-2016, and the sample is selected using purposive sampling method. The results of this study fails to prove effect of company’s ownership through pyramid structure, and related party transaction disclousure on expropriation practices. Furthermore, this study indicates the corporate governance can to increase the level of related party transactions disclosure, but has not been to reduce the expropriation practices caused by company’s ownership through pyramid structure. This  study  contributes  to  the  theory  of agency  type  II  which  discusses  conflict of interest between  controlling  and  non-controlling shareholders, and especially the problem of information asymmetry,  which can be minimized by the role of corporate governance.
Transition Strategies of Change Management For the Succesful Implementation of Data Warehouse of Higher Education in Indonesia
Authors: Iskandar Ade Rahmat , Purno Ari
Published: July 2018

Data Warehouse of Higher Education offers enormous advantages in efficiency, productivity, cost reduction and information integration system. This paper conducted to support success transition of implementation of Data Warehouse of Higher Education in Indonesia (that is called ‘Sistem Pangkalan Data Pendidikan Tinggi or PD-DIKTI in Indonesian) that had been implemented since 2013 ago. However, Data Warehouse of Higher Education implementations are complex, with many encountering difficulty and even failure. Transition of Data Warehouse implementation has been identified as critical success factor. A model that is used to manage the transition of Data Warehouse of Higher Education is Bridge’s Model, where this model is included to top ten leading transition for managing change in the world. The paper is going to summerize the results of a selected relevant articles both of the success implementation new IT technology and how to handle resistance to make transition hoped. In addition, we need to look at the transition models. The paper is hopefully able in changing the better equipped management to get satisfactory decision for all involved in implementing new IT system. This paper also conducted with Action research to get the information trusted.
Determinants of Tourism and HIV/AIDS Incidence in West Java
Authors: Heriana Cecep , Suparman Rossi , Rana Sohel , Sukmanawati Dera
Published: July 2018

Indonesia defined as tourist destination where the international and domestic tourists enjoy the tourist attractions. Prostitution existing in tourism place may increase the prevalence of HIV/AIDS. The incidence and spread of AIDS in many areas in West Java is a problem for tourism industry. These issues become acute in locations where sexual attraction is used as a determinant of tourist portability. The aim of this study was to determine relation between tourism and the incidence of HIV/AIDS in West Java. Non-reactive research design was used to collect secondary data from the Central Bureau of Statistics in 2016 from 26 districts/cities in West Java. This study was conducted in January - October 2016. Univariate and bivariate analysis methods with Spearman’s statistical test and multivariate analysis (multiple logistic) were applied. Bivariate analysis results showed the number of star hotels had p value = 0.003, r = -0.552), visit to accommodation had p value = 0.009, r = 0.499) and averageguest per day had p value = 0.022, r = 0.447. Results of multivariate analysis showed that accommodation visits had p value = 0.000). In conclusion, tourism determinants associated with the incidence of HIV/AIDS are the number of star hotels, visits to hotel, and the average guest per day.
The Influence of Exclusive Breastfeeding to Emotional Development of Children Aged 48-60 Months
Authors: Kusmiyati Yuni , Sumarah Sumarah , Dwiawati Nurul , Widyasih Hesty , Widyastuti Yani , Haji Abdul Mumin Khadizah
Published: July 2018

Impaired emotional development is a problem faced by children and this can negatively impact on function, development and readiness of their school. Exclusive breastfeeding is able to meet brain development needs that affect child development. This study aimed to determine correlation between exclusive breastfeeding and emotional development of children aged 48-60 months. This study used historical cohort.The subjects of this study were 7-12-month old infants living in area of Borobudur Primary Health Care Primary Health Care, Central Java Province, Indonesia in 2011-2012. Independent variable of exclusive breastfeeding was when infants received only breast milk without any supplementary food or drink including water since birth until the age of 6 months. Data were obtained from medical records of children. The emotional development was assessed directly by using questionnaires on emotional and mentalproblems. Data analysis used cox regression. This study found that provision of exclusive breast milk was evidently correlated with child’s emotional development. Infants who did not receive exclusive breastfeeding had 2.96 higher risk of having abnormal emotional development than infants who received exclusive breastfeeding. Exclusive breastfeeding greatly influences emotional development of the child.
Engineering Gaussian states of light from a planar microcavity
Authors: Van Regemortel Mathias , Ravets Sylvain , Imamoglu Atac , Carusotto Iacopo , Wouters Michiel
Published: July 2018

Quantum fluids of light in a nonlinear planar microcavity can exhibit
antibunched photon statistics at short distances due to repulsive
polariton interactions. We show that, despite the weakness of the
nonlinearity, the antibunching signal can be amplified orders of
magnitude with an appropriate free-space optics scheme to select and
interfere output modes. Our results are understood from the
unconventional photon blockade perspective by analyzing
the approximate Gaussian output state of the microcavity. In a second
part, we illustrate how the temporal and spatial profile of the
density-density correlation function of a fluid of light can be
reconstructed with free-space optics. Also here the nontrivial
(anti)bunching signal can be amplified significantly by shaping the
light emitted by the microcavity.
Efficacy, safety and immunogenicity of a trivalent inactivated split influenza vaccine in patients with rheumatic diseases
Authors: Bukhanova D. V. , Belov B. S. , Tarasova G. M. , Erdes Sh. , Dubinina T. V. , Lukina G. V. , Demidova N. V. , Volkov A. V. , Yudkina N. N. , Cherkasova M. V. , Diatroptov M. E.
Published: July 2018

The aim of the study was to study the efficacy, safety and immunogenicity of trivalent split influenza vaccine in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), systemic scleroderma (SSD). Material and methods. Ninety three patients were enrolled in the study, including 52 patients with RA, 34 with AS, 7 with SSD, and also 40 persons without rheumatic diseases (RD) (control group). At the time of enrolment, all patients received RD drug therapy. The duration of RD was from 2 months up to 46 years. Vaxigrip vaccine, which included the actual strains of influenza virus for the 2016-2017 or 2017-2018 seasons was administered subcutaneously in the amount of 1 dose (0.5 ml) against the backdrop of continuing RD therapy. The main stages of control were visits at 1-, 3- and 6-month intervals after vaccination. Standard clinical and laboratory tests, a clinical examination of the patient and assessment of disease activity were performed during the visits. Immunogenicity of the vaccine was evaluated at each stage of the control procedure using the commercial ELISA kits manufactured by PPDP LLC (St. Petersburg). Results. No cases of influenza or influenza-like illness were recorded during the entire period of observation. 81% of patients had no post-vaccination reactions in the RD group. Pain, swelling and hyperaemia of the skin with a diameter of up to 2 cm at the injection site were reported in 14% of cases and subfebrility, myalgia, malaise, headache in 5% of cases. The frequency of postvaccinal reactions among patients was not significantly different from that in the control group. There were no cases of exacerbation of RD or the occurrence of any new autoimmune disorders. The parameters of the humoral immune response in patients with RD did not significantly differ from those in the control group. Conclusion. The obtained data testify about good clinical efficacy and tolerability of trivalent split influenza vaccine in patients with RD.
A review of the efficacy and safety of the finished fixed-ratio combination of insulin degludec and liraglutide in the treatment of type 2 diabetes mellitus
Authors: Pogorelova A. S.
Published: July 2018

Due to the growing prevalence and progression of type 2 diabetes mellitus (DM), the researchers continue the search for the optimal drug not only to achieve the target level of glycaemic control, but also to reduce body weight and the risk of hypoglycaemic conditions. The new combinations of hypoglycaemic drugs are being developed in order to increase adherence to treatment. The studies showed that the addition of a single injection of a fixed combination of insulin degloudec/liraglutide is effective for glycaemic control and weight loss, generally well tolerated by patients and is preferred in individuals with poorly controlled type 2 diabetes on oral hypoglycaemic agents at adequate doses and/or glucagon-like peptide-1 receptor agonists and/or basal insulin to reduce the risk of hypoglycemia associated with insulin therapy.
Modern methods of prevention and treatment of postmenopausal osteoporosis
Authors: Savchenko T. N. , Aleshkin B. A. , Afanasyev S. S. , Agaeva M. I.
Published: July 2018

Osteoporosis constitutes one of the major public health problems in Russia and all over the world; this pathology has showed a tendency toward growth in recent decades. In Russia, osteoporosis was detected in 30.5-33.1% of women aged 50 years and older who underwent densitometry examination, and the incidence of proximal femur fracture for persons over the age of 50 years averages to 105.9 per 100 000. Objective of the study: evaluation of the efficacy of osteo activ in the prevention and treatment of postmenopausal osteoporosis. Materials and methods of the study: 58 postmenopausal patients were examined. In addition to general clinical examination, the concentration of total and ionized Ca, as well as vitamin D in blood plasma were determined in all patients. All examined patients were divided into two groups according to the “case-control” principle: the first group (the main group) included 35 patients who were prescribed osteo activ for the purpose of treating and preventing postmenopausal osteoporosis; the second group (the comparison group) included 23 patients, whose diet was corrected in accordance with the daily requirement of calcium and vitamin D. Results of the study: The study showed a significant increase in the calcium and vitamin D concentration in the blood plasma and a decrease in pain syndrome against the background of the therapy in patients of the main group.
Clinical measures of disability in children and adolescents due to pathology of the musculoskeletal system and connective tissue in the Voronezh region in 2015–2017
Authors: Kosenkova T. V. , Kuprina N. P. , Rushanyan A. A.
Published: July 2018

The paper presents a brief review of the primary and recurrent disability of persons under the age of 18 in the Voronezh Region in comparison with data on the Central Federal District and the Russian Federation. The article draws attention to the urgency of the comprehensive approach to diagnostics and development of measures of multilevel prevention and medical and social rehabilitation of patients and disabled persons with this pathology. It highlights the great importance of rehabilitation and habilitation for the formation or recovery of their social and professional status.
Comprehensive assessment of patients with chronic obstructive pulmonary disease by means of multicomponent ADO index and Charlson comorbidity index
Authors: Kochetova E.
Published: July 2018

The purpose of this study was to investigate the ADO index, and index of comorbidity of Charlson in patients with chronic obstructive pulmonary disease (COPD). Materials and methods: 207 patients with chronic obstructive pulmonary disease (COPD) were observed. The investigated group was made by the patients having the long experience of smoking. Research of function of external breath was studied with multimodular installation of type «Master-Lab/Jaeger». Patients were determined the index ADO and of comorbidity of Charlson. Results: The index ADO increased with stage of COPD, minimum of level ADO was observed in patients with COPD 2 stage 2,23 ± 0,88, in patients with 3 stage COPD ADO was 5,05 ± 1,19, 4 stages of COPD 7,0 ± 1,0. The correlation coefficient between ADO index and and index of comorbidity Charlson was -0,71, p <0,005. The correlation coefficient between ADO and VC was -0,57, p <0,05, between ADO and ERV was -0,63, p <0,05.
Polymorphic variants of the cholecystokinergic system genes: associations with panic disorders
Authors: Klimov E. A. , Malakhova A. V. , Korobeinikova L. A. , Azimova Yu. E. , Rudko O. I. , Kokaeva Z. G. , Korsunskaya I. M. , Sobolev V. V.
Published: July 2018

Panic disorder is a widespread socially significant disease, which genetic nature is extremely poorly known. The gene of this neuropeptide (CCK) and its receptors (CCKAR, CCK2R) have being actively studied since the discovery of panicogenic properties of cholecystokinin. The purpose of this work was to estimate the degree of incidence of seven single nucleotide substitutions in the CCK, CCKAR and CCKBR genes in the population of patients diagnosed with panic disorder and a control population consisting of unexamined residents of the Moscow region. A significant increase in the degree of incidence of the T allele of the single nucleotide substitution 109C/T (rs1805000) in the CCKBR gene was identified in the patient population as compared with the controls, prompting suggestions that this substitution is involved in the aetiology of panic disorder. It also demonstrated the association of the combination of alleles -36T CCK, -128T CCKAR (rs11571842 and rs1800908, respectively) with the development of a panic disorder.
Development of additional criteria for development of complications in patients with arterial hypertension who are carriers of the methylenetetrahydrofolate reductase gene polymorphism
Authors: Degaeva T. A. , Goncharova L. N. , Sychev I. V.
Published: July 2018

The article provides data on 114 patients with stage 2 primary arterial hypertension (AH) according to the WHO classification (2008) and the development of complications associated with hemostasis violations depending on the nationality of patients (Mordva-Moksha, Russians) and polymorphism methyltetrahydrofolate reductase (MTHFR) gene carrier state. Polymorphic genotypes were identified using polymerase chain reaction (PCR) along with traditional clinical and instrumental studies. The analysis of MTHFR gene polymorphic genotypes carriage showed a significant predominance of intermediate genotypes (88% – CT genotype at position 677, 66% – AC genotype at position 1298) regardless of nationality of patients with AH. The carriage of “unfavourable” TT genotypes of MTHFR gene at position 677 prevails in men of the Mordva-Moksha (20%) as compared with the patients of Russian nationality. During a 3-year follow-up, 12% of patients with AH (6.9% of MordvaMoksha and 5.1% of Russian) suffered acute myocardial infarction (MI) or acute cerebrovascular accident (ACVA). Cardiovascular complications (MI/ACVA) developed 1.5 times more often in Mordva patients than in patients with AH of Russian nationality. IM occurred 3 times more often in Mordva-Moksha men than in patients with AH of Russian nationality. The Mordva-Moksha men with AH, who were carriers of the “unfavourable” TT genotypes of MTHFR gene at position 677, developed a complication in the form of MI in 100% cases.
Optimization of medical care for patients with ectopic pregnancy at the prehospital stage
Authors: Ramazanova S. S. , Manukhin I. B. , Tikhomirov A. L. , Firichenko S. V.
Published: July 2018

To date, throughout the world, a gold standard for the diagnosis of ectopic pregnancy has been recognized as a study of serum at β-hCG in combination with transvaginal echography. Ectopic pregnancy takes the first place among gynecological diseases in terms of the number of diagnostic errors, especially at an early stage. Purpose of the study. Analyze the defects in the provision of medical care to patients with ectopic pregnancy at an outpatient and outpatient stage and develop an optimized approach for providing primary care to patients with ectopic pregnancy. Material and methods. A retrospective analysis of 194 patients with confirmed ectopic pregnancy according to medical records and a prospective analysis of the quality of care in 332 patients with suspected ectopic pregnancy, taking into account the identified defects according to the optimized approach. Results. Using an optimized approach in the diagnosis of ectopic pregnancy, it is possible to increase the efficiency of diagnosis on the first visit from 27,1% to 76,1%, and significantly improves the quality of primary care.
Management of patients with demension: holinergic deficiency and its correction
Authors: Lokshina A. B.
Published: July 2018

The article discusses clinical symptoms, diagnostic criteria and basic principles of managing patients with dementia. It also provides the classification of cognitive disorders by severity degrees and considers the differences between the different degrees of dementia severity. The main features of the pathogenesis of cognitive disorders in dementia, the most important approaches to managing patients with dementia are highlighted. The article presents a detailed review of modern drugs used to correct cognitive and other manifestations of dementia.
Features of autonomic regulation in cholelithiasis before and after cholecystectomy
Authors: Bagmet A. D. , Ruban A. P. , Egorov V. N. , Tayutina T. V.
Published: July 2018

It is appropriate and necessary to examine the functional state of the autonomic nervous system and the quality of life in patients with cholelithiasis using the mathematical analysis of the heart rhythm at the present-day level. Materials and methods: 136 patients (115 women and 21 men) were examined, of which 70 patients after cholecystectomy with cholelithiasis and 66 patients with cholelithiasis. Fractional chromatic minute-type duodenal intubation with an analysis of the biochemical and microscopic composition of the bile was used to assess the biliary system condition. The examination of the autonomic nervous system was carried out by determining the heart rhythm using the cardiointervalography method with further mathematical analysis of the structure and variational pulsometry. Changes in the autonomic status in patients with cholelithiasis before and after cholecystectomy differ in general patterns: adaptive possibilities decrease and sympathetic activity of the autonomic regulation increases. An increase in the lithogenicity of bile, which positively correlates with the level of sympathicotonia, is characteristic for patients with cholelithiasis before and after cholecystectomy. The autonomic regulation in patients with cholelithiasis after cholecystectomy improves, however, the high bile lithogenicity persists.
Rabeprazole in the treatment of duodenal ulcer desease and functional dyspepsia
Authors: Rusyaev V. Yu. , Sheptulin D. A. , Shulpekova N. V. , Shulpekova Yu. O.
Published: July 2018

The review aims to provide a contemporary view of the pathogenesis and treatment of the most common duodenum diseases – duodenal ulcer disease (DUD) and functional dyspepsia (FD). Due to its unique structure and functions, the duodenum that anatomically represents the initial section of the small intestine differentiates itself from others. The prevalence of DUD is declining in many Western countries due to the widespread introduction of effective anti-Helicobacter therapy and a significant decrease in the prevalence of H pylori infection. However, the ideas about the poly-biological nature of DUD persists and additional risk factors continue to be studied. DUD is manifested by pain/burning feeling in the epigastric region, as well as by symptoms such as early satiety, epigastric filling after eating in the absence of obvious organic changes in the digestive system. The diagnosis of FD is based on the Rome IV criteria. The duodenum plays an important role in its pathogenesis (disorders of gastric accommodation, motor and visceral hypersensitivity). Most patients with FD have microscopic signs of inflammation of the mucous membrane of the postbulbar part of the duodenum - an increased amount of intraepithelial lymphocytes, eosinophils, and signs of increased permeability of the mucous membrane. In all likelihood, these changes are provoked by infection and / or nutritional factors, as well as by exposure to hydrochloric acid. Proton pump inhibitors (prokinetics in postprandial distress syndrome) form the basis of treatment of peptic ulcer and epigastric pain syndrome; all patients with DUD and dyspepsia syndrome infected with H. pylori receive antihelicobacter therapy. Rabeprazole that is characterized by a long and powerful effect and minimal interaction with the cytochrome 2C19 system stands out from the proton pump inhibitors. Conclusion: acid aggression plays a very important role in the pathogenesis of duodenal ulcers diseases and FD; proton pump inhibitors form the basis for the treatment of such patients both in the form of monotherapy and as part of eradication regimens.
Change of antioxidant protection indicators in patients with osteoarthritis in the course of the treatment with a combined chondroprotective drug
Authors: Aleksenko E. Yu. , Gatiyatov Yu. F.
Published: July 2018

Objective of the study. The study of changes in some parameters of the lipid peroxidation system - antioxidant protection, lipid spectrum in the course of the long-term therapy with the combined chondroprotective drug ARTRA in patients with knee osteoarthritis (OA) Methods. 24 patients with osteoarthritis of the knee joints with 1-3 X-ray stage of the disease (Kellgren and Lawrence, 1957) at the age of 41.8 ± 6.1 years were included in an open prospective study to evaluate the effects of CCD. The following indicators in serum and erythrocytes were determined: initial products of LPO (diene conjugates (DC), ketodienes and conjugated trienes (KD and CT)) in the heptane and isopropanol phase (the method of I.A. Volchegorsky, et al, 1989); intermediates (thiobarbituric acid test modified by L.I. Andreeva, et al, 1988); catalase activity (the method of M.A. Korolyuk et al., 1988); antioxidant activity of plasma (the method of M. Promyslov, 1990); peroxide erythrocyte resistance (G.A. Yarovaya, 1987). The quantitative determination of serum total cholesterol, low-density, very-low-density, high-density lipoprotein cholesterol, triglycerides was carried out using the ready-made CORMEY standardized sets (Germany). The patients’ condition and laboratory parameters were evaluated before the study, in 12 and 24 weeks after CCD was taken. Changes in the examined indicators were documented after a 24-week course. The inhibition of lipid peroxidation processes in the form of a decrease in the primary products and intermediates in the serum and erythrocytes was established. The study showed an increase in antioxidant protection (increased activity of blood serum catalase and erythrocytes and total antioxidant activity of blood serum). The patients’ tests showed a decrease in the concentration of total cholesterol and cholesterols of low-density lipoproteins. Conclusion. The study demonstrated the positive impact of ARTRA on the LPO-antioxidant protection system and the lipid spectrum in patients with OA following the 24-week administration.
Chemical composition and nutritional quality of short-ripened rennet cheeses produced by traditional methods
Authors: KNYSZ PRZEMYSŁAW , GONDEK MICHAŁ , PYZ-ŁUKASIK RENATA , ZIOMEK MONIKA , DROZD ŁUKASZ , PASZKIEWICZ WALDEMAR , SZKUCIK KRZYSZTOF
Published: July 2018

The aim of the study was to determine the variability in the chemical composition and nutritive value parameters of smoked and unsmoked short-ripened rennet cheeses and unsmoked long-ripened rennet cheeses produced by traditional methods. The raw material for the production of short-ripened cheeses was pasteurized cows’ milk obtained from a dairy, whereas the long-ripened cheeses were manufactured from raw cows’ milk obtained from the producer’s farm. All three varieties of cheese examined were produced with commercial dairy starter cultures. The material for the study was collected in winter, directly at the producers’ retail outlets in southern and eastern Poland. The basic chemical composition was determined according to the Polish Standards, whereas the amino acid profiles of proteins from the cheeses were determined by ion-exchange chromatography. The result analysis revealed significant differences between the different varieties of cheese in terms of their water content, ranging from 32.2% to 42.1%, as well as protein content, which varied from 25.6% to 31.6%. Fat levels ranged between 22.2% and 24%, whereas total ash content amounted to 5.1-5.8%. The significantly highest salt content was found in unsmoked short-ripened cheeses. In all three cheese varieties, the total exogenous amino acid content was comparable, ranging from 46.17 g to 47.36 g/100 g protein, and that of endogenous amino acids varied from 52 g to 53 g/100 g protein. The biological value of proteins was determined by calculating to the chemical score (CS), as described by Mitchell and Block, and the essential amino acid index (EAAI), as described by Oser. A comparison of the results with the standard chicken egg white proteins showed that the limiting amino acids for all varieties of cheese were methionine and cysteine. On the other hand, a comparison with the FAO/WHO-suggested pattern of amino acid requirements (1991) for all age groups over 1 year of age showed that the limiting amino acids were methionine and cysteine in smoked and unsmoked short-ripened cheeses, and treonine in long-ripened cheeses. Considering the chemical indices, such as CS and EAAI, it may be concluded that the traditional rennet cheeses produced in southern and eastern Poland have a favourable amino acid composition of proteins and a high nutritive value..
Analyzing the Spread of Informal Employment in Russia: Reasons, Forms and Spheres of Concentration
Authors: Glinskaya M. I.
Published: July 2018

One important problem of economy at the current stage of society development is the increase in proportion of informally employed population in the total amount of labour. The prolonged trend of this indicator growth requires serious attention to this problem. Topicality of this problem is stipulated by increasing disturbance in society arising due to the growth in the number of informally employed population, non-observance of labour legislation standards and therefore, employees’ uncertainty about tomorrow. The author analyzes reasons for informal employment, identifies key spheres of its concentration and forming the full picture of problem non-uniformity. The basis of the research is formed by methods of analysis and synthesis of statistic data, which is published annually on the official portal of the Federal service of state statistics. Findings of the research shown in the article demonstrate characteristic features typical of informal employment in today’s society and analyze reasons and sphere of concentration of informally employed population. The obtained conclusions can be used as substantiation for the concept of regulating informally employed people on the territory of the Russian Federation.
Trade and Economic Cooperation of Russia and Uzbekistan at the Current Stage Ivanov I. P. The Development of Trade Platforms ETF in Europe
Authors: Goryunov I. D.
Published: July 2018

The article shows the place and role of Uzbekistan in foreign economic relations of the Russian Federation and analyzes the contract-legal foundation regulating trade and economic cooperation between the states. Special attention is paid to the structure and dynamics of goods turn-over and key lines in investment cooperation. The principle problems of trade cooperation according to the author are the low proportion of chemical industry in the structure of foreign trade, though it has a great potential of development and the pricing system of the Uzbek cotton fibre. The article shows features and priorities of Russian investment in economy of the republic, where it is possible to mention joint projects in the field of fuel and energy complex, conducting geological prospecting on the territory of the republic, developing oil-fields of hydrocarbon fuel and its transportation. As a conclusion the article provides the assessment of trade and economic cooperation between the countries, identifies prospects of further collaboration: deepening inter-regional links, broadening the range of mutual delivery of manufactured products, widening lines of Russian investment (coal industry, electric-power engineering, radio-technical and electronic industry). In order to study the impact of different factors on bilateral relations of cooperation the author used the empiric method, which includes analysis of statistic materials, study of documents, first of all multi-sided agreements and contracts and investigation of conceptual approaches of academics, practical experts and specialists in international problems.
Off-Shoring Processes in Conditions of Taxation System Restructuring
Authors: Bratcev V. I. , Roybu A. V. , Pozhidaeva E. S.
Published: July 2018

The article analyzes off-shoring processes in order to find new ways for developing taxation planning oriented to prevention of asset outflow beyond Russian jurisdiction due to the taxation system restructuring. The authors showed the necessity to decline the appeal of off-shore for entities of economic activity based on rational taxation legislation. They substantiate the topicality of researching the taxation system restructuring in Russia, which fosters business development and new taxation mechanism designing providing conditions for reduction of off-shore development. Key forms of taxation incentive were investigated in order to identify possibilities of their impact on de-off-shoring processes and grounding the necessity of developing a new taxation mechanism for extending tax payments on growth of capital till the completion of the investment process. The article considers the taxation manoeuvre towards increasing the taxation base and its feasibility in Russian conditions. The article describes priorities of Russian taxation policy and its improvement in today’s circumstances of complicated geopolitical situation and sanction restrictions. The authors come to the conclusion about Russia transition to a row of innovation countries and put forward a set of measures aimed at creating optimal conditions of all economic agents’ involvement in innovation activity and filling economy with innovation content. Among key results of the research we should mention grounding taxation system restructuring, which stimulates business development and designing practical recommendations aimed at improvement of the mechanism of taxation impact on off-shore processes.