bluuebunny/crossref_metadata_2025 huggingface dataset:
Tsinnisna Rationality is Like a Clear Ambush of Managing the Anti-Crisis State Government Policy
Authors: Zadorozhna О.G.
Published: March 2022

The need for a cardinal change in the management of anti-corrosion and anti-coronavirus transformations of the current crisis system and the state’s gratitude become a priority for economic, social, and management people science. The light has already changed dramatically. The new head managers have a lot of people who are guilty of being guilty of all the administrative decisions of the national districts, as well as the supranational institutes. The price of the need for a reason is that it is the most important for people to take economical management decisions and take an active part in the government’s government processes, and the smell is the first for all the highly rational, moral, and spiritually-gratifying The goal is to achieve proof-of-concept, how the management of anti-crisis transformations of the dastardly government can be effective and successful for the mind, since such transformations are carried out in the context of the cultural and cultural field of comprehension of the present-day people. The very protection and protection of the people of the present year becomes the head vector and the field of management activities. For the rationalization of human management, it should mean, but not sensible, separate problems: environmental, economic, social, military, psychological, etc., in the life of people and suspensions. The state through the stem of the governing bodies is the same as the poklikan osyagati-intelligence, so the unity of the whole vikhoditiy from such intelligence with the vikonanny of its own attribute ‒ the zahol’y administrative function of development. Orієntir-tsil ‒ ob’єdnannya ‒ the head moment is not deprived of the theoretical comprehension of the state in the mental field of integrity, but the main directly її practical steps to ensure the development of an integral national state-owned complex.
Features of Venture Financing of the Prydniprovsky Economic Region under Creating of an Ecosystem for Innovative Investment
Authors: Lyakh I.I.
Published: March 2022

The paper is devoted to the assessment of the condition of regional venture funds in the Prydniprovsky Economic Region. As they are the main investors of innovative enterprises, it is needed to be develop such institutions not only in the Central Polissya economic region with the capital of Ukraine, but also in the Prydniprovsky economic region as well in other economic regions.
It is proved that Ukraine is more active in producing innovative products compared to the level of investing in innovation. In current conditions, this fact indicates the necessity of promoting the development of venture investment institutions to ensure the proper functioning of an ecosystem for innovative investing on the regional level.
Ensuring the innovative development in the regions cannot be limited by investments in innovation or by procurements of the modern equipment and technologies, but a set of conditions must be created for an effective innovation policy of economic entities located in the region. The analysis showed that foreign venturers usually invest in economic activities in the Prydniprovsky economic district only for the first three to five years at the beginning of new company incipience. This requires balanced changes in in such policies as for science and technology, innovation and investment, which are necessary to intensify the innovative activities of business entities, attracting investment in all sectors of the regional economy.
Despite significant changes in legislation towards European practice, there is still a long and difficult way to go before the investment climate in Ukraine warms up. The long-term efforts required by innovation activating necessarily involve a favourable environment at both the national and regional levels.
The priority and effective direction of investment policy improvement is the gradual successful implementation of large-scale investment projects. Attracting influential foreign investors to the Ukrainian market and effectively supporting such projects will help improve Ukraine’s image in the global capital market and attract long-term investments.
Invisible Bias in Nominating and Selecting Gifted Students
Authors: Aljughaiman Abdullah , Albosaif Waleed
Published: March 2022

One objective of gifted education is to provide fair opportunities for all children, including access to the nomination and selection procedures for gifted programs and services. This study aims to identify invisible biases in the nomination of gifted students in the National Gifted Identification Project (Mawhiba Test) during the periods of 2014, 2015, and 2017. The participants were limited to students nominated in Al Ahsa, in the Eastern Province of Saudi Arabia, which includes students from rural, urban, and settlement schools. There was a total sample of 74,199 male students and 74,097 female students. The study followed the descriptive approach, and the Chi-square test was used to measure whether the location variable (i.e., the school’s location) was independent of the number of candidates. The results showed a significant correlation between the location and the number of male and female candidates. Additionally, the results indicated a significant decrease in the percentage of male and female students in settlement schools, which requires the relevant authorities to reconsider the procedures followed in nomination and selection, especially in remote areas and settlements.
KEYWORDS
Gifted students, disadvantaged students, rural, urban, settlement schools, Mawhiba Test, underrepresentation
Educational Robots and Creative Thinking Skills
Authors: Alrobia Renad , Alsaleh Nada
Published: March 2022

This research aimed to investigate the effectiveness of using educational robots in extra-curricular projects to enhance creative thinking skills among students. To achieve this aim, a semi-experimental approach was followed, which involved training students to design and program an educational robot and use different cognitive skills derived from all their academic courses to solve a problem. The research sample consisted of (16) students in the fifth grade of Smart Learning Primary School. They were randomly divided into two equal groups: a control group and an experimental group. The Torrance Test of Creative Thinking, form (B), was used as a tool for this research to determine any improvement in the students' creative thinking skills. The results showed statistically significant differences between the experimental and the control groups when their creative thinking skills – fluency, flexibility, and originality – were tested after they had used educational robots in extra-curricular projects, even taking into account several factors that could have increased their skills in these areas. This research recommends expanding the use of educational robotics activities to develop higher-order thinking skills among students. The research also recommends providing teachers with adequate training and technical support to employ robotics technology in education.
KEYWORDS
Artificial intelligence, 21st-century skills, problem-solving skills, learning activities, educational programming, higher thinking skills, robotics
Ecological trends of modern marketing activity
Authors: IHNATENKO Roman
Published: March 2022

The paper examines the essence of environmental marketing and the main environmental trends of marketing activities in modern business conditions. It has been established that environmental marketing is marketing aimed at meeting the needs of the target audience through products that help protect the environment. The main goal of this activity is to popularize ecological products and form responsible consumption among users, ie to make ecological goods the standard of consumption. The goals and objectives of environmental marketing are: raising environmental awareness among consumers; development and promotion of ecological goods; promotion of environmentally friendly goods and services on the market; formation of eco-needs on the market; greening of production. Five main environmental trends of modern marketing activities of enterprises are identified, which include the following: PR and creating a positive image of the company, increasing customer loyalty, creating new environmental goods and services, attracting influencers, implementing waste-free or safer production methods. At the same time, it is established that the main eco-trend in Ukraine is the choice of consumers of goods, information about the origin of which is transparent and reliable. There are also five scenarios for using environmental trends in modern business marketing. In particular, such scenarios define - care for recycling and reuse of products, building exclusively eco-brand, introduction of certain eco-products (premium) in the product range, use of modern technologies for production and maintenance, introduction of waste-free or safer production methods. The practice of implementation of ecological trends of marketing activity on the example of cases of world and domestic companies is investigated. Prospects for further research are to determine the economic and social effectiveness of the principles of environmental marketing.
Simulación de “compton imaging” con Geant4 y su aplicación en la Medicina
Authors: Nieto-Chaupis Huber , Catalán-Sánchez Elías
Published: March 2022

En este reporte presentamos los resultados de una investigación realizada con el software GEANT4, que es usado ampliamente en física de altas energías y que tiene aplicaciones también en las áreas de la medicina no invasiva. Nos centramos en el llamado Compton Imaging, que permite reconstruir en 3D la composición de tejidos humanos a partir de interacciones cuánticas de fotones con materia. Se simula el haz de fotones de 500 keV que colisiona con tejido humano y la reconstrucción de los fotones dispersados, que es llevada a cabo con una simulación de un detector basado en Germanio; presumimos que el detector está a unos pocos centímetros de la región de interacción. Para el presente estudio, los resultados muestran que el Compton Imaging requiere de baja dosificación, del orden de 0.5 mSv, si lo comparamos con tomografías que requieren más de 1 mSv para un área de 25 cm2. Esto significaría dos aspectos positivos: menos riesgo de exposición a radiación para pacientes que necesitarían varias sesiones dentro de un esquema de terapia oncológica, y un posible aumento de la probabilidad de éxito mientras dura el tratamiento.
OBSERVED CONSUMER ORIENTED MARKETING STRATEGIES OF ORGANIC PRODUCTS VARIABILITY AND CHANGES OVER TAMILNADU
Authors: Begam M. Shamsath
Published: March 2022

Eco farms vision is to nurture just and ecologically sustainable farms and food systems through education and advocacy. This research on eco farm covers the marketing strategies for organic producers. Farmers marketing for operations that sells through farmers markets or other direct to consumer. Today farmers supply fruits and vegetables to the farmers market, supermarkets local grocery stores and restaurants. It is responsible business that cares about environment their product and consumer. They are present online that analyzed competitor using aerator criteria, reliability assurance, tangible empathy and responsiveness. Make the online store more trustworthy and there is a wide range of organic products. Eco farm will send it out by email as well as posted on their web page. In these role farmers applies their expertise to help navigate complex organic compliance decisions and works to ensure organic farmers. Organic producer has experienced hardship in marketing during the pandemic period, point out them in this paper to market in sustainable food
EFFECT OF STRENGTH AND PLYOMETRIC TRAINING ON PHYSICAL FITNESS VARIABLES OF COLLEGE FEFEMALE VOLLEYBALL PLAYERS
Authors:   Director of Physical Education, Nehru Arts and Science College (Autonomous),  (Affiliated to Bharathiar University) Coimbatore, Tamilnadu, India., SAKTHIVEL Dr. A , RAMESH Dr. A ,   Director of Physical Education,  RVS College of Engineering and Technology, Coimbatore, Tamilnadu., VINAYAGAMOORTHI Mr. A ,   Ph.D Scholar,Dept of Physical Education, Bharathiar University, Coimbatore, Tamilnadu, India.
Published: March 2022

The purpose of the study was to find out the effect of strength and plyometric training p on physical fitness variables of college Female Volleyball players.To achieve the purpose of the study 30 subjects were randomly selected from Karpagam Academy of Higher Education (Deemed to be University) Coimbatore, Tamilnadu, were selected randomly as subject for this study. The subjects were randomly assigned to two equal groups (n=15). Purpose of thirty Female Volleyball players selected from, All the subjects were divided in to two groups with Fifteen (15) subjects each as experimental and control group. The selected subjects were divided into two equal groups with 15 subjects in each group. The experimental group-I (N=15) underwent strength training and control group (N=15) did not undergo any practices the data were collected before and after the training period of 8 weeks and the data collected were statistically analysed with ‘t’ ratio, which was used to find out the significant difference on selected physical fitness variables of arm strength and leg strength. Strength training programme showed significant improvement in arm and leg strength
The Vital Role of Cloud Healthcare During COVID-19 Pandemic
Authors: Adnan Amen
Published: March 2022

The most sharable tag on social media was “stay at home”. Where, the governments oblige their residents from physical meeting or traveling instead of this they have to stay at their home for controlling the wide speared of The novel Corina Virus (COIVD-19). Hence, many lives are being saved. Here, Cloud Computing act as a game changer in many institutions and countries demand particularly to healthcare organizations. This Paper will review cloud health applications such as Telehealth, Telemedicine supporting with mobile cloud health applications. And the important role of sharable the cloud informatics in health. Then it focuses on the role of cloud played in health care sector to saving life’s during COIVED -19. Not only for people who have been infected but also for assisting other older people to get their treatment. Some concerns are existing to discuss related with security, outages, privacy and monitoring issues or when matter went wrong during the Telemedicine appointment with suggested solution for future matters.
Eurasian clinical guidelines for cardiovascular complications of cancer treatments: diagnosis, prevention and treatment (2022)
Authors: Chazova I. E. , Ageev F. T. , Aksenova A. V. , Vicenya M. V. , Gilyarov M. Yu. , Martynyuk T. V. , Panchenko E. P. , Poltavskaya M. G. , Potievskaya V. I. , Trofimova O. P. , Fedotkina Yu. A.
Published: March 2022

Disclaimer. The EAC Guidelines represent the views of the EAC, and were produced after careful consideration of the scientific and medical knowledge, and the evidence available at the time of their publication. The EAC is not responsible in the event of any contradiction, discrepancy, and/or ambiguity between the EAC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to good use of healthcare or therapeutic strategies. Health professionals are encouraged to take the EAC Guidelines fully into account when exercising their clinical judgment, as well as in the determination and the implementation of preventive, diagnostic, or therapeutic medical strategies; however, the EAC Guidelines do not override, in any way whatsoever, the individual responsibility of health professionals to make appropriate and accurate decisions in consideration of each patient’s health condition and in consultation with that patient and, where appropriate and/or necessary, the patient’s caregiver. Nor do the EAC Guidelines exempt health professionals from taking into full and careful consideration the relevant official updated recommendations or guidelines issued by the competent public health authorities, in order to manage each patient’s case in light of the scientifically accepted data pursuant to their respective ethical and professional obligations. It is also the health professional’s responsibility to verify the applicable rules and regulations relating to drugs and medical devices at the time of prescription.
Pulmonary arterial hypertension: challenges and achievements 2021
Authors: Rezukhina E. A. , Martynyuk T. V. , Valieva Z. S. , Gramovich V. V. , Chazova I. E.
Published: March 2022

Symposium dedicated to pulmonary arterial hypertension took place at the 9th Russian Congress on Pulmonary hypertension on December 14, 2021. In this review key points from Chazova I.E., Martynyuk T.V., Valieva Z.S., Gramovich V.V.`s reports are presented, in which information about PAH treatment goals achievement, COVID-19 pandemic challenges impact on routine clinical practice is demonstrated. In this review current situation in pulmonary arterial hypertension treatment goals and regular risk stratification importance are observed, based on the latest clinical trials combined specific therapy including selective prostacyclin receptor agonist selexipag is demonstrated. special attention is paid to pulmonary hypertension patients’ treatment during COVID-19 pandemic, regular risk stratification necessity is mentioned including remote patient monitoring in order to perform timely escalation in PAH-specific treatment in order to achieve low-risk status and to improve the prognosis of PAH patients.
Cardiovascular diseases in patients with psoriasis in clinical practice: case report. Eurasian heart journal
Authors: Kuzmina O. A. , Mironova O. Iu. , Fomin V. V.
Published: March 2022

Psoriasis is a genetically determined multifactorial disease that affects about 2% of the population. According to modern concepts of this disease, the level of comorbid diseases, especially those associated with damage to the cardiovascular system, is high. This article presents a clinical case of severe disseminated psoriasis vulgaris, progressive stage, mixed form in a patient with a very high cardiovascular risk. The uniqueness of this clinical case lies in the combined course of psoriasis and such comorbid diseases as: severe hypertension, obesity, dyslipidemia, type 2 diabetes mellitus (DM), hyperuricemia. The main clinical manifestations were the presence of widespread lesions on the patient’s skin, episodes of discomfort behind the sternum during physical activity, as well as destabilization of blood pressure numbers (maximum rise to 180/100 mm Hg). As part of the hospitalization in the skin clinic, the patient underwent topical ointment therapy with the use of glucocorticoid ointments, ointments containing salicylic acid, PUVA therapy, as a result of which the skin process showed positive dynamics with regression of lesions by 90-100% with an outcome in residual hyperpigmentation, no new lesions were noted. During hospitalization to a therapy department, the optimal antihypertensive, lipid-lowering, uricosuric, hypoglycemic therapy was selected, as a result of which it was possible to achieve an improvement in the patient’s condition, stabilization of blood pressure at the level of 130-140/70 mm Hg. So patients with psoriasis require careful assessment of cardiovascular risk in clinical practice. A multidisciplinary approach will not only improve the quality of life of patients, reduce the likelihood of major cardiovascular events, but also increase life expectancy and reduce mortality.
Antivirals against HCV infection: the story thus far
Authors: Irekeola Ahmad Adebayo , EAR Engku Nur Syafirah , Mohd Amin Nur Amalin Zahirah , Mustaffa Nazri , Shueb Rafidah Hanim
Published: March 2022

Remarkable scientific breakthroughs have been made in the stride towards the development of potent and tolerable hepatitis C regimens within the last three decades. Earlier approaches involved the use of pegylated interferon alfa and ribavirin as standard-of-care treatment. Treating genotype 1a infection with this regimen which was at that time considered the gold standard for hepatitis C virus therapy was rife with challenges; safety and toxicity issues necessitated a rigorous quest for alternative regimens. Deeper understanding of the pathogenesis of hepatitis C virus ushered in the era of direct acting antiviral agents. These agents have been the subject of intensive research in the last two decades, leading to the development of drug classes such as protease inhibitors (e.g., grazoprevir), NS5A inhibitors (e.g., daclatasvir) and NS5B inhibitors (e.g., sofosbuvir). While many are still under development, several have been approved for hepatitis C therapy. A number of studies investigating the combination of direct acting antiviral agents with or without pegylated interferon and/or ribavirin for the treatment of chronic hepatitis have demonstrated sustained virologic response of > 90%. Given the array of direct acting antiviral agents currently available, the present landscape of hepatitis C therapy is now characterized by a gradual transition to all-oral interferon-free regimens. Despite these milestones, the WHO global target of eliminating hepatitis C as a public health problem by 2030 seems uncertain. In this review, we provide a concise account of the evolution and advancements in the development of anti-HCV regimens.
A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital
Authors: Dell’Aversana Orabona Giovanni , Togo Giulia , Calvanese Carlo , Ferri Andrea , Committeri Umberto , Improta Giovanni , Iaconetta Giorgio , Califano Luigi
Published: March 2022

Introduction: Nowadays, with the start of the vaccination campaign is very important to assess the extent of exposure of the population and identifying rapid, sensitive and accurate test to quickly identify new cases of SARS-CoV-2. The rapid test, cheap and easy to perform, is therefore very useful in developing countries, where the vaccination campaign has not yet reached adequate coverage.

Methodology: We compared the VivaDiag COVID-19 IgM/IgG Rapid Test (VivaCheck Biotech Co., Ltd) with the Roche Elecsys Anti-SARS-CoV-2 (Roche Diagnostics, Rotkreuz, Switzerland) to recognize past infections and to compare VivaDiag COVID-19 IgM/IgG Rapid Test (VivaCheck Biotech Co., Ltd) with Abbott Real Time PCR SARS-CoV-2 assay to recognize infection during its acute phase so that it’s possible to evaluate the use of commercially available assays in clinical practice.

Results: Of the 1,100 patients tested with serological and rapid test, 1,085 were negative both to serological and rapid test, 4 patients were positive at rapid (2 for IgM and 2 for IgG) but negative serological test, 11 patients were positive at serological test but negative to rapid.

Of the 300 tested with oropharyngeal swab and rapid test, 294 were negative both to swab and rapid test, 2 positives both to swab and rapid test, 3 positives at swab but negative at rapid test, 1 negative at swab but positive at rapid test.

Conclusions: the combined use of these tests according to the specific needs of users, allows a reliable identification of infected patients in the acute phase, distinguishing them from subjects with an antibody response from a previous infection.
The clinical significance of antiphospholipid antibodies in COVID-19 infection
Authors: Atalar Ebru , Erden Abdulsamet , Guven Serdar Can , Armagan Berkan , Ates İhsan , Küçüksahin Orhan , Omma Ahmet
Published: March 2022

Introduction: One of the factors that may aggravate the clinical presentation in COVID-19 is the increased level of antiphospholipid antibodies (aPLs) and thrombotic events that can be seen with the disease. In our retrospective study, we aimed to evaluate the effect of aPLs on the clinical findings in patients with a diagnosis of COVID-19.

Methodology: Seventy-three patients diagnosed with COVID-19 and examined for aPLs were included in the study. Patients were divided into two groups according to the test results of aPLs. Clinical and laboratory parameters were compared in both groups to reveal whether there was any difference between the groups.

Results: There were 15 patients with a positive aPLs test. Dyspnea, nausea, vomiting, myalgia, and abdominal pain were significantly higher in the aPLs positive group than those with negative aPLs. The duration of hospital stays and the need for oxygen therapy of the patients in the aPLs positive group were significantly higher than the aPLs negative group. However, no difference was found between the two groups in terms of mechanical ventilation need, intensive care admission rate, thrombosis and mortality. In terms of laboratory findings, those with positive aPLs have higher median C-reactive protein (CRP) and ferritin values than those with negative aPLs.

Conclusions: In our study group, we could not find a relationship between aPLs positivity and critical complications. According to our hypothesis, it may not be necessary to routinely examine aPLs in patients with a diagnosis of COVID-19 to determine the risk of thromboembolic complications.
Relationship between Smell and Taste Impairment Function among COVID-19 Patient in General Hospital of Adam Malik Medan
Authors: Nasution Iskandar , Youlpi Indah Mutiara
Published: March 2022

BACKGROUND: Decrease of smell-taste has become a cardinal symptom of COVID-19. Some previous studies have reported that most of the COVID-19 patients complained of early smell-taste impairment. AIM: Hence, this study was aimed to investigate the relationship between smell and taste impairment against PCR test results. METHODS: This study was an observational study with a cross-sectional study among 193 patients who were diagnosed as COVID-19 that had smell-taste impairment between March and August 2020. Parameters were evaluated in this study included age, sex, ethic, occupation, smell-taste impairment, coagulation state, comorbid condition, obesity, and the result of the swab PCR test. The relationship between smell and taste impairment and the PCR test result was analyzed by Chi-square and regression logistic. RESULTS: This study showed that most COVID-19 patients were female (32.1%) aged 18−40 years old (25.9%). Meanwhile, the most comorbid condition owned by the COVID-19 patient in the General Hospital of Adam Malik Medan was diabetes, followed by hypertension, cardiovascular disease, and stroke. Moreover, this study also revealed that the smell (adjusted OR: 3.92; 95% CI: 1.30−11.87) and taste (adjusted OR: 3.64; 95% CI: 1.30−10.22) impairment significantly associated with COVID-19 (p < 0.05) CONCLUSION: Overall, it can be concluded that the smell-taste impairment can be used to early symptoms to predict the COVID-19 with the positive PCR test result.
Comparison between Interleukin-2 Serum Levels and Positive and Negative Syndrome Scale Scores of Schizophrenia Patients that Received Haloperidol with Risperidone Therapy
Authors: Tanra Andi Jayalangkara , Liaury Kristian , Hajai Novianti , Zainuddin Andi Alfian , Lisal Sonny T. , Soraya Gita Vita , Syamsuddin Saidah
Published: March 2022

BACKGROUND: There is a possibility of interleukin-2 (IL-2) being involved in the pathophysiology of Schizophrenia. The increase of IL-2 levels has been discovered in the serum of schizophrenic patients in earlier studies. An amount of antipsychotic has been associated with the decrease of IL-2. AIM: Therefore, this study was intended to compare the serum IL-2 levels of schizophrenic patients who received Haloperidol therapy with patients who received Risperidone as well as examine the relationship between serum IL-2 levels with the positive and negative syndrome scale (PANSS) score of schizophrenic patients receiving Haloperidol and Risperidone therapy. METHODS: This study is an observational study with a prospective cohort design consisting of 36 patients who have met the Diagnostic and Statistical Manual of Mental Disorders 5th Edition criteria for Schizophrenic patients who did not take antipsychotic drugs for 2 weeks and were hospitalized at the Special Hospital of South Sulawesi Province. Afterwards, the patients were grouped into two groups, where each group consisted of 18 people, namely, the group of patients who received Haloperidol and the group of patients who received Risperidone, and then were furtherly evaluated until the 4th week. The sample examination method used was enzyme-linked immunosorbent assay to see the blood serum IL-2 levels. Clinical symptoms of Schizophrenia were assessed using the PANSS score. RESULTS: The study showed that serum IL-2 levels decreased at the 4th week after conducting antipsychotic therapy among both groups. The decrease in PANSS scores in the Risperidone group was greater compared to the Haloperidol group at week 3 and week 4. In the serum IL-2 levels difference of the group who received Risperidone therapy, the decrease was greater than those receiving Haloperidol therapy (3.72 ± 1.30 ng/ml vs. 2.43 ± 1.39 ng/ml, p = 0.008). In addition, based on the correlation test, no significant correlation was present between the difference in the total PANSS score and the difference in the serum IL-2 levels within the Haloperidol group (p = 0.059, r = 0.453) and the Risperidone group (p = 0.518, r = 0.113). Schizophrenic patients have higher serum IL-2 levels than healthy people. Schizophrenic patients who received antipsychotics for 4 weeks experienced a decrease in serum IL-2 levels. Risperidone administration had a higher decrease in serum IL-2 levels than Haloperidol. CONCLUSION: Changes in serum IL-2 levels as a consideration of one of the Biomarkers are still needed for further evaluation. The therapeutic role of Haloperidol and Risperidone can be attributed as anti-inflammatory in Schizophrenia but cannot be attributed to improvement in the psychopathological status of Schizophrenic patients.
Chronic Prostatitis: Impact of Lifestyle, Infection, and Inflammation on Semen Parameters
Authors: Puerta Suárez Jenniffer , Velázquez Rivera Valentina , Morales Mateo , Alvarez Angela M. , Carvajal Alejandro , Cardona Maya Walter D.
Published: March 2022

Chronic prostatitis is a widespread disease of the prostate affecting men’s sexual and reproductive health worldwide. Its leading causes are urogenital tract infections by microorganisms with a prostate tropism. This study aimed to evaluate semen parameters and the factors associated (lifestyle, urogenital infections, and inflammation) with the onset of chronic prostatitis symptoms. This case-control study included seventy-six donors: 30 volunteers with chronic prostatitis and 46 asymptomatic volunteers for urogenital infections as a control group. Sociodemographic, urinary symptoms, pain location, sexual and reproductive health and lifestyle-related variables were collected in a survey. Seminal quality, cytokine levels in semen and serum, and the presence of nineteen microorganisms in the urogenital tract were evaluated. Prostatitis was also associated with poor sperm morphology, more lipoperoxidation of the sperm membrane, and lower serum nitric oxide concentration. In addition, N. gonorrhoeae infection was detected more frequently in semen samples from volunteers with chronic prostatitis. Volunteers with chronic prostatitis report more frequently erectile dysfunction and premature ejaculation, anxiety, depression, and stress compared to the control group. Chronic prostate infections alter the microbiota from the genitourinary tract causing prostatitis, a disease that affects all life areas, including the familiar environment of patients. Chronic prostatitis affects seminal parameters, with a great impact on life quality and sexual and reproductive health. Despite being a relatively unexplored disease, much remains to be clarified regarding its diagnosis and treatment. Alterations in the genitourinary microbiota can favor sexually transmitted infections that produce chronic and systemic inflammation.
Role of Interventional Radiology in the Management of Obstructive Jaundice: Achieving Drainage and Stenting
Authors: Mohson Khaleel I. , Kadhum Zaid Hadi
Published: March 2022

BACKGROUND: Obstructive jaundice due to the central malignant cause is really challenging for gastroenterologists and usually results in failed drainage of obstructing system, the percutaneous transhepatic biliary drainage (PTBD) usually results in a dramatic pathway opening.

AIM: The study aimed to evaluate the role of interventional radiology (IR) in achieving drainage of obstructing system and subsequent reduction of serum bilirubin and its role in stenting the obstructing lesion.

METHODS: A prospective study included 40 patients who complained of obstructive jaundice referred to IR unit in specialties surgical hospital from gastroenterology hospital after failed endoscopic drainage and stenting during the period from September 2020 to November 2021.

RESULTS: Of 40 patients in study population, 26 are male and 14 females, their median age was 65 years, cholangiocarcinoma is leading cause of biliary obstruction, the technical success of PTBD was 100% and clinical success achieved by lowering of total serum bilirubin by 60% within 2 weeks seen in 75% of the patients, no significant major complications seen after procedure, and only 5% of the patients developed leaking bile along the drain tract.

CONCLUSIONS: PTBD and transhepatic biliary stenting are amazing technique in acute and chronic management of patients with obstructive jaundice, achieve dramatic lowering of serum bilirubin, fighting biliary sepsis and long-term palliation of advanced biliary, pancreatic, and ampullary malignancy.
Influence of Self-esteem and Preparation for Aging on the Happiness of Older Thai Adults: A Cross-sectional Study
Authors: Nanthamongkolchai Sutham , Phowat Theerawat , Munsawaengsub Chokchai , Suksatan Wanich
Published: March 2022

Background: Happiness is necessary for older adults’ physical and psychological well-being. The objective of this study was to examine the associations of self-esteem and preparation for aging with happiness and to determine the predictive factors of the happiness of older Thai adults.
Methods: The study had a cross-sectional predictive correlational design and included 225 older Thai adults aged 60–69 years selected using multi-stage random sampling. Data were collected through self-administered questionnaires, and the collected data were analyzed using frequency, percentage, Pearson’s product moment correlation coefficient, and multiple regression analysis.
Results: The study results showed that 64.9% of the study participants were moderately happy. The factors that significantly influenced their happiness were self–esteem and preparation for aging (p < 0.05), meaning their self–esteem and preparation for aging were able to predict their happiness, accounting for approximately 67.0% of the variance of such happiness.
Conclusion: Older adults’ healthcare providers should organize activities for enhancing older adults’ self-esteem and for helping them prepare well for old age.
Invading of Renal Cell Carcinoma in Inferior Vena Cava and Right Atrium with a Huge Metastatic Thrombus
Authors: Kacani Andi , Goga Marsela , Kuci Saimir , Aliu Arber , Ibrahimi Alfred , Gjergo Petrika , Janko Aurel , Dogjani Agron
Published: March 2022

BACKGROUND: Renal cell carcinoma (RCC) with cavoatrial involvement represents a major surgical challenge. Several surgical techniques for the treatment of these tumors have been proposed, but due to a small number of patients and limited follow-up, substantial controversy about the best operative management still exists.

CASE REPORT: A 54-year-old woman, with no previous comorbidities, comes to the emergency room with low back pain, weight loss, and edema of the lower legs that computed tomography revealed a massive infiltrative expansive formation in the abdomen that affected practically the entire right kidney, measuring 8.2 cm × 7.6 cm that invaded the collecting system and was in close contact with the right hepatic lobe and the head of the pancreas. During the intervention, infiltration of the renal vein on this side is found, and the inferior vena cava (IVC) that extends in its intrahepatic part, up to the junction of the suprahepatic veins, with almost complete closure of the lumen accompanied by the presence of retroperitoneal lymph nodes, with size up to 10 mm.

CONCLUSION: Advanced extension of RCC can occur with no apparent symptoms and be detected incidentally. In rare circumstances, atypical presentation of RCC should be considered in a patient presenting with the right atrial mass detected by echocardiography. RCC with IVC and right atrium extension is a complex surgical challenge, but excellent results can be obtained with proper patient selection, meticulous surgical techniques, and close perioperative patient care.
Association between Administration of Systemic Corticosteroids and the Recovery of Olfactory and/or Gustatory Functions in Patients with COVID-19: A Prospective Cohort Study
Authors: Gamil Yasmine , Ismail Radwa M. , Abdou Ahmed , Shabaan Alshaimaa A. , Hamed Mohamed G.
Published: March 2022

AIM: This study is a prospective cohort study aimed to assess the effect of systemic corticosteroids administration time in the recovery of gustatory and olfactory sensations dysfunction (ageusia and anosmia) in COVID-19 patients.

MATERIALS AND METHODS: Sixty-seven COVID-19 patients with symptoms of ageusia and anosmia were recruited (that their COVID infection was confirmed using polymerase chain reaction). Daily 10 mg of systemic corticosteroids were prescribed in the 1st week and then reduced to 5 mg in the 2nd week to all the patients to observe taste and smell sensation recovery. All data were recorded and then analyzed. Patients were then grouped into two groups (early and late groups) according to the duration of their taste and smell dysfunction.

RESULTS: Regression analysis showed that early corticosteroid administration resulted in a significant decrease in recovery time of ageusia and anosmia (0.27 [0.2–0.35], p < 0.001). Patients in the early administration group (<1 week) showed faster improvement in regaining taste and smell functions than in the late administration group (>1 week) with significant difference (p < 0.001).

CONCLUSIONS: The use of systemic corticosteroids in early phases of covid-19 infection help in faster recovery of ageusia and anosmia.
Second-Trimester Cervico-Isthmic Pregnancy after Donor Egg In Vitro Fertilization, Complicated with Placenta Accreta – Case Report
Authors: Kovachev Emil , Anzhel Simona , Zhekov Zhivko , Tabakova Nikoleta , Dimova Silviya
Published: March 2022

BACKGROUND: Cervical gestations are rare potentially life-threatening conditions. Although these can cause massive hemorrhage, most of them abort during the first trimester without having been diagnosed. However, cervico-isthmic pregnancies are more likely to persist to an advanced gestation in the second and third trimester owing the need for hysterectomy due to defect placentation.

CASE PRESENTATION: We presented a rare case of cervical pregnancy after donor egg in vitro fertilization procedure, with no previous pregnancies, medical, and surgical history. Our patient rejected early termination of pregnancy at 5 gestational weeks. Pregnancy continued until 16 weeks when she was hospitalized and terminated due to medical grounds with curettage. Post-operative period was uneventful until day 20, when she was admitted with suspicion of retained placental tissue and endometritis. A hysterectomy was done with blood transfusion due to excessive blood loss. Histologic examination confirmed placenta accreta spectrum disorder.

CONCLUSION: Cervical pregnancy can be treated conservative if timely diagnosed by early ultrasound, which can reduce the chances of severe life-threatening hemorrhage necessitating hysterectomy or blood transfusion.
Regularity of Pythagorean neutrosophic graphs with an illustration in MCDM
Authors: Ajay D. ,   Department of Mathematics, Sacred Heart College, Tirupattur - 635601, Tirupattur Dt., Tamilnadu, India, Chellamani P. , Rajchakit G. , Boonsatit N. , Hammachukiattikul P. ,   Department of Mathematics, Faculty of Science, Maejo University, Chiang Mai 50290, Thailand,   Department of Mathematics, Faculty of Science and Technology, Phuket Rajabhat University, Phuket 83000, Thailand,   Department of Mathematics, Faculty of Science and Technology, Rajamangala University of Technology Suvarnabhumi, Nonthaburi 11000 Thailand
Published: March 2022

Pythagorean neutrosophic set is an extension of a neutrosophic set which represents incomplete, uncertain and imprecise details. Pythagorean neutrosophic graphs (PNG) are more flexible than fuzzy, intuitionistic, and neutrosophic models. PNG are similar in structure to fuzzy graphs but the fuzziness is more resilient when compared with other fuzzy models. In this article, regular Pythagorean neutrosophic graphs are studied, where for each element the membership $ (\mathfrak{M}) $, and non-membership $ (\mathfrak{NM}) $ are dependent and indeterminacy $ (\mathfrak{I}) $ is independently assigned. The new ideas of regular, full edge regular, edge regular, and partially edge regular Pythagorean Neutrosophic graphs are introduced and their properties are investigated. A new MCDM method has been introduced using the Pythagorean neutrosophic graphs and an illustrative example is given by applying the proposed MCDM method.
Determinantal inequalities for block Hadamard product and Khatri-Rao product of positive definite matrices
Authors: Dong Sheng , Wang Qingwen , Hou Lei
Published: March 2022

In this paper, we first give an alternative proof for a result of Liu et al. in [Math. Inequal. Appl. 20 (2017) 537–542]. Then we present two inequalities for the block Hadamard product and the Khatri-Rao product respectively. The inequalities obtained extend the result of Liu et al.
Stability analysis and optimal control of COVID-19 with quarantine and media awareness
Authors: Zhang Jiajia ,   Faculty of Science, Beijing University of Technology, Beijing 100124, China, Qiao Yuanhua , Zhang Yan
Published: March 2022

In this paper, an improved COVID-19 model is given to investigate the influence of treatment and media awareness, and a non-linear saturated treatment function is introduced in the model to lay stress on the limited medical conditions. Equilibrium points and their stability are explored. Basic reproduction number is calculated, and the global stability of the equilibrium point is studied under the given conditions. An object function is introduced to explore the optimal control strategy concerning treatment and media awareness. The existence, characterization and uniqueness of optimal solution are studied. Several numerical simulations are given to verify the analysis results. Finally, discussion on treatment and media awareness is given for prevention and treatment of COVID-19.
Representing reggaeton through fans' online community archives
Authors: Chalk Lauren
Published: March 2022

Communities of fans are collaboratively approaching the task of preserving the materials, memories, and histories of reggaeton, a popular music genre. Two online spaces, the Hasta 'Bajo project and the Reggaeton Con La Gata platform, provide examples of community archives founded by fan-scholars. These initiatives invite participation, recognition, and celebration of reggaeton, in turn constructing and revising histories of the genre, in response to institutional and dominant discourses. This intervention, which speaks broadly to ideas on fan initiatives, frames the convergence between archivism and activism within these spaces as oriented toward the pursuit of cultural justice.
Binding fan fiction and reexamining book production models
Authors: Buchsbaum Shira Belén
Published: March 2022

Binding fan fiction into books is an increasingly popular phenomenon that follows in the footsteps of twentieth-century fanzines and challenges the current perception of fic as an exclusively digital form. Fan binders complicate book historical notions of bookmaking as a commercially driven enterprise by infusing it with affective connotations that rearrange the book production model of Robert Darnton's communication circuit. The notion of a fan fiction communication circuit extends Darnton's model to account for the noncommercial, reciprocal practices of fan fiction production. Members of Renegade Bindery, a community of fan binders on Discord, provide testimony regarding their philosophy, technique, and motivation that paints a complex picture of contemporary private bookbinding practices that construes value for printed works through affective labor rather than commercial return.
Opinions of University Students on Technology Literacy
Authors: Saltanat Adikanova , Kaldykul Sarbassova , Zaure Kabdrakhmanova , Saniya Kubentayeva , Gulbanu Uristenbekova , Karas Kaziyev , Bagdat Baimukhanbetov
Published: March 2022

The aim of this study is to evaluate the views of engineering faculty students on technology literacy. This research was conducted using a qualitative research design. In accordance with the structure of the research, the phenomenology design was chosen from the qualitative research designs. The study group of the research consisted of 142 students studying at engineering faculties at various universities in Kazakhstan and who voluntarily agreed to participate in the research. In the study, the opinions of engineering faculty students on technology literacy were collected with a semi-structured interview form developed by the researchers. As a result of the research, students defined technology literacy as knowing the meaning and function of technology and using it effectively. In addition, they associated technology use in the profession with technology competencies and professional competencies. The majority of students put forward the knowledge of technology in technological competencies and being able to follow technological innovations in professional competencies as a prerequisite for the use of technology in the profession. The students participating in the research found themselves moderately competent in being technology literate. Technology literacy should be integrated with all curricula and the content of curricula should be arranged accordingly.
United States Participation in the European Project Semester
Authors: Abata Duane L.
Published: March 2022

This chapter describes successful interaction between engineering colleges in the United States and similar institutions engaged in the European Project Semester program, EPS, throughout Europe. Dr. Abata was asked to both teach and serve in the administration of EPS. The EPS program described herein was designed to promote student exchange and student interaction between EPS institutions in a multidiscipline environment in Europe. The primary purpose of EPS is to address engineering design in junior and senior years. Several students from the United States participated in this primarily European program for the benefit of broadening their educational and career horizons as well as gain valuable insight into international approaches to engineering design. These students commented that their experience was significant. However, meeting engineering senior design requirements in some cases was problematic due to the interpretation of ABET senior design requirements. This chapter concludes with a brief discussion of the possibility of EPS like-programs in the United States.