bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Sistem Distribusi Air Bersih di Komplek Perumahan Cemara Hijau Medan
Authors: Nasution Ikhwan Fauzi , Indrawan Ivan , Faisal Muhammad
Published: September 2023

Cemara Hijau Housing Complex is an elite housing complex located on the outskirts of Medan which each year has an increasing number of consumers not followed by increased network capacity and clean water supply. This study aims to analyze the pattern of water consumption of customers in the Green Pine complex, analyzing the availability of PDAM Tirtanadi water of Cemara branches with water needs of Cemara Hijau customers and analyzing the clean water distribution system in Cemara Hijau housing using Hardy Cross method with Hazen William and Epanet 2.0 equations. The research method used is to first conduct literature studies related to clean water distribution system and Epanet 2.0 application. Then collect the required data that is primary data and secondary data. Then the data data is analyzed by manual calculation of Hardy Cross with Hazen William equation and using computer software that is Epanet 2.0. The result of research is the pattern of clean water consumption in the green pine complex with the highest factor is 1.69 while the lowest is 0.21, then the water loss at the Cemara Hijau Housing Complex is 52.93%, then the clean water distribution network system in the Cemara Hijau Housing Complex does not meet in terms of flow and pressure, so that the solution given is the addition of 50 mm diameter made in parallel, the last of the total difference obtained from Epanet 2.0 with a large enough field for the hourly of 0.0766 m3/sec and for 24 hours of 4.3878 m3/sec, and the total difference between Epanet 2.0 with Hardy Cross method with Hazen William equation is not too large with a total difference of 0.00048 m3/sec or 0.48 liter/sec.
OS CUIDADOS PALIATIVOS NA VISÃO DE INTERNOS DE UM CURSO DE MEDICINA: ESTUDO TRANSVERSAL
Authors: Bruch Daniele , Ribeiro Elaine Rossi , Haddad Maria do Carmo Fernandez Lourenço , Malaquias Tatiana da Silva Melo , De Almeida Marcio José
Published: September 2023

Este estudo teve por objetivo verificar o conhecimento de estudantes de medicina sobre cuidados paliativos em saúde durante a sua formação. Método: Estudo transversal com 58 participantes dentre um universo de 200 internos de medicina dos quatro últimos períodos da graduação (internato médico) de uma instituição de ensino superior brasileira privada sem fins lucrativos, que tem um currículo integrado com o uso intensivo de metodologias ativas de ensino-aprendizagem. Foi utilizado um questionário, enviado por meio eletrônico e que foi baseado no instrumento americano "Physician's End-of-Life Care Attitude Scale”. A coleta de dados ocorreu no terceiro trimestre de 2020 e os dados foram analisados por meio da estatística descritiva simples. Resultados: Participaram 58 estudantes, entre 20 e 34 anos, sendo 72% mulheres. Apenas 15,5% se consideraram competentes em dar notícias ruins. Quanto ao manejo clínico, 65,5% necessitaram maior supervisão ou instrução básica na dispneia terminal. Na decisão de retirada do suporte ventilatório de um paciente incapaz de decidir por si, 74,1% se preocuparam com questões legais e profissionais e 77,6% com questões éticas. Em relação ao pensamento sobre a morte do paciente, 67,2% se manifestaram ansiosos ou desconfortáveis. 80% dos estudantes classificaram como importante ou muito importante abordar a temática dos cuidados paliativos durante o internato. Conclusão: Os estudantes expressaram graus variados de conhecimento acerca do tema. Manifestaram maior segurança no manejo dos principais sintomas clínicos. Observou-se que o tema morte provoca certo grau de angústia e desconforto nos estudantes, que consideram necessário o conhecimento sobre cuidados paliativos.
FORMAÇÃO EM PSICOLOGIA E QUALIDADE DE VIDA: DISCUSSÕES SOBRE A PROMOÇÃO DA SAÚDE MENTAL DOS UNIVERSITÁRIOS
Authors: Bereta Thaísa Angélica Déo da Silva , Do Vale Mariana Aguiar
Published: September 2023

Refletir como a Formação em Psicologia vem acontecendo e os impactos desta sobre a qualidade de vida e saúde mental dos universitários, foi o foco central das discussões da presente pesquisa. Para tanto, esta configura-se como exploratória, observacional e descritiva de corte transversal, com 45 estudantes de Psicologia, sendo 30 do primeiro termo e 15 do nono termo da graduação em Psicologia de uma Instituição de Ensino Superior. Foram utilizados o Critério de Classificação Econômica (CCEB) e o World Health Organizacional Quality of Life (WHOQOL – BREF). Dos participantes, 46,67% foram classificados na classe econômica B2. Quando perguntado como os acadêmicos de primeiro termo se autoavaliavam em relação à qualidade de vida, 30% avaliaram como Muito Boa, 56,67% como Boa e 13,33%, Nem Ruim Nem Boa. Em relação ao nono termo, 66,67% avaliaram como Boa, 13,33%, Nem Ruim Nem Boa e 20% como Ruim. Não houve diferença estatística em relação aos domínios Físico, Psicológico, Relações Sociais e Meio Ambiente, porém, no domínio Autoavaliação da qualidade de vida, os graduandos do primeiro termo apresentaram melhores resultados. Há necessidade de mais pesquisas para o entendimento da qualidade de vida dos universitários e o quanto a sobrecarga vivenciada pode ser um fator que impacta significativamente a formação profissional. Contudo, reforça-se a importância dos serviços de apoio destinados aos graduandos, a fim de ampliar e consolidar ações voltadas para a promoção da saúde mental e qualidade de vida, para haver um processo ensino-aprendizagem comprometido com os sujeitos e com as relações estabelecidas.
O EFEITO PROVOCADO PELA SIRENE NA SAÚDE DOS PROFISSIONAIS DE BATALHÕES DO CORPO DE BOMBEIROS
Authors: Novanta Gabriela Guenther Ribeiro , De Carvalho Junior Edvaldo Ceripes , De Souza Murilo Silva , Farias Natália Rodrigues , Boger Marlene Escher
Published: September 2023

Introdução: O ruído é um som que provoca efeitos nocivos ao ser humano, sendo uma sensação auditiva desagradável que interfere na percepção do som desejado. Indivíduos expostos a níveis elevados de ruídos por um longo período de tempo podem sofrer danos mentais, socias e físicos. Os bombeiros são uma classe profissional que está frequentemente exposta a ruídos, dentre eles, de sirenes, veículos, ferramentas e alarmes. Objetivo: Investigar o efeito provocado pela sirene na saúde dos profissionais dos batalhões do Corpo de Bombeiros do Distrito Federal. Método: Foi aplicado questionário para avaliar o desconforto gerado pelo ruído e feita medição dos níveis de pressão sonora dos veículos e equipamentos utilizados em resgate. Foram aplicados os testes estatísticos pertinentes, adotando o nível de significância menor que 0,05. Resultados: O ambiente de trabalho foi classificado, na presente pesquisa, como ruidoso por 80,5 % dos participantes, sendo que 72% destes o classificaram como moderado e 15% como excessivo. As queixas mais citadas após a entrada na incorporação foram alteração no sono, o desconforto com sons altos, a intolerância e a irritabilidade. O tempo de serviço, como profissional do Corpo de Bombeiros, interferiu nas questões emocionais relacionadas a aspectos de estresse e distúrbios do sono. Conclusão: O ruído excessivo pode desencadear queixas auditivas e extra-auditivas nos bombeiros. Isso pode causar irritabilidade, distúrbios do sono e desconforto com sons altos. Dessa forma, é imprescindível a implementação de medidas de proteção, visando prevenir efeitos deletérios à saúde dos profissionais.
PERCEPÇÕES DA EQUIPE MULTIPROFISSIONAL SOBRE CUIDADOS PALIATIVOS: UMA REVISÃO
Authors: Maranhão Francisca Yone Farias , Doroteu Tatiana Nogueira , Andrade Ítalo Rigoberto Cavalcante
Published: September 2023

Os cuidados paliativos multidisciplinares objetivam a melhoria da qualidade de vida do paciente por meio da prevenção e alívio do sofrimento, identificação precoce, avaliação impecável e tratamento da dor e de outros sintomas. O objetivo do estudo foi compreender a percepção da equipe multiprofissional sobre cuidados paliativos na Unidade de Terapia Intensiva. Realizou-se uma revisão de literatura no período de agosto a outubro de 2022, nas bases de dados BVS, SciELO, LILACS, BDENF e Medline. A amostra final foi constituída por cinco artigos científicos selecionados mediante critérios pré-estabelecidos. Os resultados revelam percepções de diversos aspectos que interferem na assistência ao paciente em cuidados paliativos, dentre eles, estruturais, organizacionais e de conhecimento. A importância da preparação da equipe multiprofissional que cuida dos pacientes em cuidados paliativos foi reforçada pelos estudos avaliados. Conclui-se que cada profissional tem um papel fundamental na promoção da assistência humanizada aos pacientes em cuidados paliativos e seus familiares.
OS DESAFIOS DA ASSISTÊNCIA INTEGRAL DA MULHER NEGRA NA ATENÇÃO BÁSICA: UMA QUESTÃO DE SAÚDE PÚBLICA
Authors: Oliveira Lívia Matos , Oliveira Nathally Costa , Santos Lara Beatriz Pierote , De Lima Jessane Thifanny , Duarte Larissa da Silva , Gonçalves Maria Luiza da Silva , Coelho Lara Beatriz de Sousa , Oliveira Francisco  Braz Milanez
Published: September 2023

Objetivo: Analisar os paradigmas enfrentados pela população negra feminina no sistema de saúde na Atenção Primária, identificando os principais fatores que impedem uma melhor acesso e assistência. Método: Trata-se de uma revisão integrativa de literatura, com busca nas bases de dados da Medline, BDENF, LILACS, utilizando como descritores: “Saúde da Mulher”, “Atenção Primária a Saúde”, “Saúde Pública” e “Política de Saúde” combinados entre operadores boleanos AND e OR, com recorte temporal dos últimos 5 anos. Resultados: Dos 4.541 artigos encontrados, 8 foram selecionados para compor o estudo. Identificaram-se, como desafios à assistência à saúde integral da mulher negra no âmbito da Atenção Básica fatores relacionados ao despreparo dos profissionais mediante as vulnerabilidades e a falta de educação continuada, que se tornam questões limítrofes e desafiadoras enfrentadas pelas mulheres diariamente. A existência de preconceito racial, ainda que fortemente combatida, ainda existe nas instâncias da sociedade e necessita de intervenção nas instituições de saúde visando atender o indivíduo considerado sua integralidade. Fatores socioeconômicos relacionados à moradia da mulher também foram destaque apontados no estudo, revelando um processo de lentidão para realizar exames e acompanhamento dos profissionais. Conclusões: Uma vez que a Atenção Básica é porta de entrada do sistema de saúde, permanece a necessidade de ampliar o arcabouço científico de pesquisas para compreender a temática específica e adequadamente, pois é indubitável que a mulher negra enfrenta várias lacunas para uma assistência sem iniquidades.
ANALISIS PEMBENTUKAN PORTOFOLIO OPTIMAL MENGGUNAKAN MODEL BLACK LITTERMAN DENGAN PENDEKATAN ARCH/GARCH
Authors: Antika Rindi , Satyahadewi Neva , Perdana Hendra
Published: September 2023

Kegiatan investasi memiliki keterkaitan dengan return dan risiko sehingga dibutuhkan upaya untuk mengoptimalkan return dan meminimalkan risiko yaitu menyusun portofolio. Salah satu model pembentukan portofolio adalah Black Litterman. Penelitian ini dilakukan untuk membentuk portofolio optimal menggunakan model Black Litterman, menganalisis prediksi views investor model Black Litterman menggunakan model ARCH/GARCH, dan memperoleh nilai return dan risiko portofolio. Model Black Litterman mengkombinasikanviews investor dan return equilibrium. Data penelitian diperoleh dari website yahoo finance, yaitu saham-saham yang tergabung dalam Indeks LQ-45 periode 1 Februari sampai 31 Juli 2021. Kombinasi saham untuk membentuk portofolio dilakukan dengan memilih empat saham dengan expected return tertinggi dan berdistribusi Normal. Berdasarkan penelitian diperoleh saham AKRA, ANTM, ITMG dan JPFA sebagai kombinasi saham pembentuk portofolio model Black Litterman. Hasil penelitian menunjukkan bahwa views investor saham AKRA diprediksi dengan model GARCH(1,2) kemudian saham ANTM dengan model GARCH(2,1), ITMG dengan model GARCH(1,2) dan JPFA dengan model ARIMA(0,1,2). Portofolio model Black Litterman saham AKRA memiliki proporsi sebesar 27,89%, ITMG dengan proporsi sebesar 26,55% dan JPFA dengan proporsi sebesar 45,56%. Hasil pembobotan untuk saham ANTM diperoleh nilai negatif yang mengindikasikan mengalami risiko kerugian sehingga saham ANTM tidak diberikan proporsi bobot. Portofolio model Black Litterman yang terbentuk menghasilkan expected returnsebesar 0,00999 dan mengalami risiko portofolio sebesar 0,00034.
Switchable organocatalysis from N-heterocyclic carbene-carbodiimide adducts with tunable release temperature
Authors: Pham Le Dung , Smith-Sweetser Red , Krupinsky Briana , Dewey Carolyn , Lamb Jessica
Published: September 2023

N-Heterocyclic carbenes (NHCs) are powerful organocatalysts, but practical applications often require in situ generation from stable precursors that “mask” the NHC reactivity via reversible binding. Previously established “masks” are often simple small molecules, such that the NHC structure is used to control both catalytic activity and activation temperature, leading to undesirable tradeoffs. Herein, we show that NHC-carbodiimide (CDI) adducts can be masked precursors for switchable organocatalysis and that the CDI substituents can control the reaction profile without changing the NHC structure. Large electronic variations on the CDI (e.g., alkyl versus aryl) drastically change the catalytically active temperature, whereas smaller perturbations (e.g., different para-substituted phenyls) tune the catalyst release within a narrower window. This control was demonstrated for three classic NHC-catalyzed reactions, each influencing the NHC-CDI equilibrium in different ways. Our results introduce a new paradigm for controlling NHC organocatalysis as well as present practical considerations for designing appropriate masks for various reactions.
Reverse-Engineered High-Yield Lasso Peptide Production in an Alternative Host
Authors: Fernandez Hannah , Kretsch Ashley , Kunakom Sylvia , Kadjo Adjo , Mitchell Douglas , Eustaquio Alessandra
Published: September 2023

The knotted configuration of lasso peptides confers thermal stability and proteolytic resistance, addressing two shortcomings of peptide-based drugs. However, low isolation yields hinder the discovery and development of lasso peptides. While testing Burkholderia sp. FERM BP-3421 as a bacterial host to produce the lasso peptide capistruin, an overproducer clone was previously identified. In this study, we show that an increase in plasmid copy number partially contributed to the overproducer phenotype. Further, we modulated plasmid copy number to recapitulate titers to an average of 160% relative to the overproducer, which is 1,000-fold higher than previously reported with E. coli, reaching up to 240 mg/L. To probe the applicability of the developed tools for lasso peptide discovery we targeted a new lasso peptide biosynthetic gene cluster from endosymbiont Mycetohabitans sp. B13, leading to the isolation of mycetolassin-15 and mycetolassin-18 in combined titers of 11 mg/L. These results validate Burkholderia sp. FERM BP-3421 as a production platform for lasso peptide discovery.
Anion-templated synthesis of a switchable fluorescent [2]catenane with sulfate sensing capability
Authors: Bąk Krzysztof M. , Trzaskowski Bartosz , Chmielewski Michał J.
Published: September 2023

Anion templation strategies have facilitated the synthesis of various catenane and rotaxane hosts capable of strong and selective binding of anions in competitive solvents. However, this approach has primarily relied on positively charged precursors, limiting the structural diversity and the range of potential applications of the anion-templated mechanically interlocked molecules. Here we demonstrate the synthesis of a rare electroneutral [2]catenane using a powerful, doubly charged sulfate template and a complementary diamidocarbazole-based hydrogen bonding precursor. Owing to the unique three-dimensional hydrogen bonding cavity and the embedded carbazole fluorophores, the resulting catenane receptor functions as a sensitive fluorescent turn-ON sensor for the highly hydrophilic sulfate, even in the presence of large excess of water. Importantly, the [2]catenane exhibits enhanced binding affinity and selectivity for sulfate over its parent macrocycle and other acyclic diamidocarbazole-based receptors. We demonstrate also, for the first time, that the co-conformation of the catenane may be controlled by reversible acid/base induced protonation and deprotonation of the sulfate anionic template. This approach pioneers a new strategy to induce molecular motion of interlocked components using switchable anionic templates.
Asymmetric Migratory Hydroarylation for the Concise Synthesis of Chiral α-(Hetero)Aryl-Substituted Amines
Authors: Zhou Junqian , He Yuli , Liu Zihao , Zhu Shaolin
Published: September 2023

Complementary to design of a single structurally complex chiral ligand to promote each step in transition-metal catalysis, multiligand relay catalysis through dynamic ligand exchange with each step in the catalytic cycle promoted by its best ligand provides an attractive approach to enhance the whole reaction reactivity and selectivity. Herein, we report a regio- and enantioselective NiH-catalyzed migratory hydroarylation process with a simple combination of a chain-walking ligand and an asymmetric arylation ligand, producing high value chiral α-(hetero)aryl-substituted amines and their derivatives under mild conditions. The potential synthetic applications of this transformation are demonstrated by the concise synthesis of (S)-nicotine and a CDK8 inhibitor.
Controlled Synthesis of Polycarbonate Diols and Their Polylactide Block Copolymers using Amino-bis(phenolate) Chromium Hydroxide Complexes
Authors: Ni Kaijie , Dawe Louise , Sarjeant Amy , Kozak Christopher
Published: September 2023

A diamine-bis(phenolate) chromium(III) complex, CrOH[L] ([L] = dimethylaminoethylamino-N,N-bis(2-methylene-4,6-tert-butylphenolate)), 2, in the presence of tetrabutylammonium hydroxide effectively copolymerizes CO2 and cyclohexene oxide (CHO) into polycarbonate diol. The resultant low molecular weight (6.3 kg mol–1) diol is used to initiate ring-opening polymerization of rac-lactide with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) giving ABA-type block copolymers with good molecular weight control through varying rac-LA-to-diol loading, and with narrow dispersities. As the degree of rac-LA incorporation increases, the glass transition temperatures (Tg) are found to decrease, whereas decomposition temperatures (Td) increase. Diphenylphosphonimido)triphenylphosphorane (Ph2P(O)NPPh3) was used as a neutral nucleophilic cocatalyst with 2, giving phosphorus-containing polycarbonates with Mn of 28.5 kg mol–1, dispersity of 1.13, Tg of 110 C and Td over 300 C. A related Cr(III) complex (4) having a methoxyethyl pendent group rather than a dimethylaminoethyl group was structurally characterized as a hydroxide-bridged dimer.
Coupled-Cluster Density-Based Many-Body Expansion
Authors: Focke Kevin , Jacob Christoph
Published: September 2023

While CCSD(T) is often considered the ``gold standard'' of computational chemistry, the scaling of its computational cost as N^7 limits is applicability for large and complex molecular systems. In this work, we apply the density-based many-body expansion [Int. J. Quantum Chem. 2020, 120, e26228] in combination with CCSD(T). The accuracy of this approach is assessed for neutral, protonated, and deprotonated water hexamers as well as (H2O)16 and (H2O)17 clusters. For the neutral water clusters, we find that already with a density-based two-body expansion, we are able to approximate the supermolecular CCSD(T) energies within chemical accuracy (4 kJ/mol). This surpasses the accuracy that is achieved with a conventional, energy-based three-body expansion. We show that this accuracy can be maintained even when approximating the electron densities using Hartree-Fock instead of using coupled-cluster densities. The density-based many-body expansion thus offers a simple, resource efficient, and highly parallelizable approach that makes CCSD(T)-quality calculations feasible where they would otherwise be prohibitively expensive.
Manufacturing Scale-Up of Anodeless Solid State Lithium Thin Film Battery for High Volumetric Energy Density Applications
Authors: Cheng Diyi , Tran Khanh , Rao Shoba , Wang Zhongchun , van der Linde Richard , Pirzada Shahid , Yang Hui , Yan Alex , Kamath Arvind , Meng Ying Shirley
Published: September 2023

Compact, rechargeable batteries in the capacity range of 1-100 mAh are targeted at form-factor-constrained wearables and other high-performance electronic devices, which have core requirements including high volumetric energy density (VED), fast charging, safety, surface-mount technology (SMT) compatibility and long cycle life. Solid-state lithium thin film batteries (TFB) fabricated on thin substrates and packaged in a multilayer stack offer these attributes, overcoming the limitations of lithium-ion batteries based on liquid electrolytes. To maximize the VED, an anodeless architecture fabricated using a roll-to-roll process on an ultrathin stainless-steel substrate (10-75 um in thickness) has been developed. These microbatteries use a lithium cobalt oxide (LiCoO2) cathode and lithium phosphorus oxynitride (LiPON) electrolyte deposited by thin film techniques to enable key battery performance metrics. A high-device-density dry-process patterning flow defines customizable battery device dimensions while generating negligible waste. The entire fabrication operation is performed in a conventional, humidity-controlled cleanroom eliminating the need for a costly dry-room environment that allows for simplified, lower-cost manufacturing. Such scale-up using an anodeless architecture also enables a thermal-budget-compatible packaging and metallization scheme targeted at industry-compatible SMT processes. Further manufacturability improvements such as the use of high-speed tests add to the overall range of elements necessary for mass production. A perspective on requirements and opportunities for this technology as it evolves is provided.
Investigation of the time effect on the nanozyme-mediated oxidation of 3, 3’-diaminobenzidine by hydrogen peroxide
Authors: Hormozi Jangi Saeed Reza
Published: September 2023

Time effect on the nanozyme-mediated oxidation of 3, 3’-diaminobenzidine by hydrogen peroxide was investigated. Silver-based nanomaterials were synthesized and then used as peroxidase mimics. The time-dependent activity of the 3, 3’-diaminobenzidine oxidation catalyzed by silver-based nanomaterials was calculated by probing the color intensity of the produced brown-colored indamine polymer during the reaction at different time intervals. The time-dependent activity curve was used as an index for evaluating the time effect on the process, showed that the concentration of the brown-colored indamine polymer was increased by increasing the oxidation time and then leveled off, revealing saturation of active nodes of nanoparticles with nanozyme-substrate.
Rapid rescoring and refinement of ligand-receptor complexes using REMD with a MC pose reservoir
Authors: Alcantara Juan , Chiu Kelley , Bickel John , Rizzo Robert , Simmerling Carlos
Published: September 2023

Virtual screening (VS) involves generation of poses for a library of ligands, and ranking using simplified energy functions and limited flexibility. Top scored poses are used to rank and prioritize ligands. Here we adapt the reservoir replica exchange molecular dynamics (res-REMD) method to re-rank poses generated through VS. REMD simulations are carried out, but with occasional Monte Carlo jumps to alternate VS-generated poses using a Metropolis criterion. The simulations converge within 10 ns for all systems, generating populations of alternate poses in the context of fully flexible ligand and protein side chains. The protocol is applied to four model protein-ligand complexes, where DOCK resulted in two successes and two scoring failures. In all four systems, the most populated cluster from the final ensemble exhibits high similarity to the crystallographic pose, with ligand RMSD values under 2.0 Å. Both DOCK failures were rescued. For one DOCK success, the protocol identified the correct pose, but also sampled an alternate pose at equal probability. Opportunities for future improvement and extension are discussed.
An investigation on significance of adoption and implementation of IFRS for SMEs in malawi among non-incorporated construction companies: A study of selected SMEs in blantyre
Authors: Hastings Kumwenda
Published: September 2023

SMEs have come to accept the importance of harmonizing accounting information to remain in today's business environment. Hence, for better continuation of rendering their services, SMEs are required to keep books of accounts bound by the statutory rules of Malawi. In 2009, the IASB developed and published IFRS for SMEs in response to the need for high-quality internationally comparable and transparent financial information. The objectives of the study were to investigate the significance associated with the adoption and implementation of IFRS (International Financial Reporting Standards) for SMEs among non-incorporated construction companies in Malawi, to measure the extent of adoption, the mechanism to promote adoption, and related problems for the adoption of IFRS for SMEs. To achieve the determined objectives, the study was conducted and the questionnaire guides were distributed. The sample was selected based on non-probability sampling from the greater area of Blantyre contractors coming up with 30 participants. The collected facts were analyzed using SPSS to obtain tables, pie charts and bar graphs from which conclusions, recommendations as well as areas for further research were made. The investigation revealed that 60% of the construction companies did not adopt IFRS for SMEs. Little effort has been made by the council to encourage the adoption of IFRS for SMEs. The benefits one could accrue in adopting the standard include building strong investors and other stakeholders' confidence, enhancing comparability, and easy access to bank loans due to better credit rating, tax compliance, increased transparency, and accountability, and played a big role in making effective decisions. This study recommends the need for continuous education, awareness campaigns, and communication to contractors on issues associated with IFRS for SMEs and should commence in earnest. Furthermore, a rigorous IFRS for SMEs capacity-building programs should be embarked upon by regulatory bodies (the NCIC in corroboration with ICAM) and training institutions to provide the required manpower for the successful implementation of the IFRS for SMEs.
Effect of Vitamin E Supplemented with Calcium in the Treatment of Hypertension During Pregnancy on Maternal and Infant Outcomes
Authors: Li Yanjun
Published: September 2023

Objective: To investigate the effect of vitamin E supplemented with calcium in the treatment of hypertension during pregnancy on maternal and infant outcomes. Methods: 60 patients with gestational hypertension admitted from January 2020 to December 2022 were recruited and randomly divided into the control group and the observation group, each group including 30 patients. The control group was given routine treatment, whereas the observation group was given routine treatment combined with vitamin E-supplemented calcium therapy, and both groups received treatment until delivery. The clinical effects of the observation group and the control group after treatment, systolic and diastolic blood pressure, mean arterial pressure, urine protein, blood lipid levels at different time points (before and after treatment), and maternal and child outcomes during treatment were uniformly compared and analyzed. Results: After treatment, the total clinical effective rate (93.33%) of the observation group was significantly higher than that of the control group (70.00%); compared with before treatment, the systolic blood pressure, diastolic blood pressure, mean arterial pressure, urine protein, TC, and TG levels of the two groups were all lower after treatment, and the observation group was at a lower level; there was no significant difference in the incidence of hemorrhage (P > 0.05). Conclusion: Vitamin E supplemented with calcium has a significant effect on the treatment of hypertension during pregnancy, which can help reduce blood pressure and blood lipid levels, reduce urinary protein content, improve maternal and child outcomes, and improve safety.
Analysis of the Influence of Knee Joint Balancing Manipulation on the Rehabilitation of Patients after Total Knee Arthroplasty
Authors: Zhang Tian , Li Hua , Dong Xiaohua , Zhang Dakuan
Published: September 2023

This paper aims to explore the clinical effect of knee-balancing manipulation after total knee arthroplasty. A total of 84 patients with total knee arthroplasty in our hospital were selected. The time of admission and treatment was from March 2021 to March 2023. They were divided into the study group (n = 42) and the control group (n = 42) by lottery method with a digital table. The patients in the control group received conventional rehabilitation, and the patients in the study group received balancing manipulation of the knee joint. The Hospital for Special Surgery (HSS) knee function score and gait indicators were compared between the two groups. The HSS score of patients in the study group was higher than that in the control group at 2 weeks after operation (P < 0.05). The gait indexes of patients in the study group were higher than those in the control group at 2 weeks after operation (P < 0.05). Knee-balancing manipulation after total knee arthroplasty can improve knee joint function and restore gait, which has the value of popularization and application.
Clinical Value of Tranexamic Acid Combined with Total Knee Arthroplasty in the Treatment of Knee Osteoarthritis
Authors: Zhang Fei , Zhang Jieyong
Published: September 2023

This paper aims to explore the clinical value of tranexamic acid combined with total knee arthroplasty (TKA) in patients with knee osteoarthritis (KOA). The research period was from March 2020 to December 2022. A total of 50 samples of KOA patients were selected and divided into the study group (n = 25) and the control group (n = 25) by lottery method of medical record envelopes. The patients in the control group were treated with TKA, and the patients in the study group were treated with tranexamic acid combined with TKA. The surgery-related indicators, visual analogue pain score (VAS), inflammatory factor levels, motor function scores, and incidence of complications were compared between the two groups. The intraoperative blood loss in the study group was lower than that in the control group (P < 0.05), and there was no significant difference in postoperative hospital stay between the two groups (P > 0.05). The postoperative VAS scores in the study group were lower than those in the control group (P < 0.05), while the postoperative inflammatory factor levels of the study group were lower than those of the control group (P < 0.05). The postoperative motor function scores of the study group were higher than those of the control group (P < 0.05), and the incidence of complications in the study group was lower than that in the control group (P < 0.05). The treatment of KOA patients with tranexamic acid combined with TKA can reduce intraoperative blood loss, relieve pain, reduce the level of inflammatory factors, improve postoperative motor function, and reduce the incidence of complications, which can be widely applied in clinical practice.
Comparison of the Clinical Effects of Internal Fixation Combined with Vertebroplasty and Internal Fixation Alone on Patients with Spinal Fractures
Authors: Chen Chen
Published: September 2023

Objective: This study aims to explore and analyze the comparison of clinical treatment effects of internal fixation combined with vertebroplasty and internal fixation alone on patients with spinal fractures. Methods: The experimental time was from April 2021 to April 2023. 80 spinal fracture patients treated by spinal surgery in our hospital were used as research objects, and grouped by double-blind method into study group (n = 40) and control group (n = 40). The study group received internal fixation combined with vertebroplasty, and the control group received internal fixation alone. The restoration of spinal structure, treatment, surgical treatment index, and incidence of adverse events were compared between the groups. Results: Before operation, the Cobb angle of the affected vertebra, the degree of spinal canal invasion, and the compression ratio of the prevertebral height of the two groups were compared, and there was no statistically significant difference (P > 0.05). The

degree of compression and the compression ratio of the affected prevertebral height in the study group were significantly better than those of the control group, and the difference was statistically significant (P < 0.05). The rating of the treatment situation in the study group was significantly higher than that of the control group, the difference was statistically significant (P < 0.05). The surgical treatment indicators such as tissue bleeding volume, hospitalization time, and intraoperative operation time in the study group were significantly better than those in the control group, and the difference was statistically significant (P < 0.05). The incidence of adverse events in the study group was significantly lower than that in the control group, and the difference was statistically significant (P < 0.05). Conclusion: Internal fixation combined with vertebroplasty is more effective than internal fixation alone in treating spinal fractures.
Analysis of the Risk of Basilar Aneurysm Rupture Based on CTA Morphological Parameters
Authors: Zhang Guoping , Chen Xiaoli
Published: September 2023

Objective: To investigate morphological risk factors of basilar aneurysm rupture based on computer tomography angiography (CTA) parameters. Materials and methods: The clinical and CTA data of 43 patients with basilar aneurysm admitted to Shaanxi Provincial People’s Hospital from January 2015 to July 2023 were analyzed. The patients were divided into “ruptured group” and “unruptured group,” and the morphological parameters of aneurysms were measured. The general data and morphological parameters between the two groups were statistically analyzed. Logistic regression was used to analyzed statistically significant parameters, and the receiver operating characteristic curve was drawn to evaluate its diagnostic effectiveness. Results: Irregular aneurysms were more likely to rupture than regular aneurysms (x² = 13.971, P < 0.05). The maximum diameter (4.92 [3.37–6.94] mm), length-width ratio (1.31 [1.14–1.55]), height (4.08 [2.71–5.34] mm), aspect ratio (0.99 [0.84–1.45]), and inflow angle (133.63 ± 11.21°) of aneurysms in the ruptured group were larger than the unruptured group, and the differences were statistically significant (P < 0.05). Binary logistic regression showedthat aneurysm shape (OR = 39.347, P = 0.021), length-width ratio (OR = 313.062, P = 0.033), and inflow angle (OR = 1.156, P = 0.004) were independent risk factors for rupture. The area under the curve were 0.809, 0.842. and 0.894, respectively. Conclusion: Aneurysm shape, aspect ratio, and blood flow incidence angle are independent risk factors for basilar aneurysm rupture, which means that they can be used to predict the risk of rupture to a certain extent.
Clinical Effect Analysis of Small and Medium Doses of Betaloc Combined with Amiodarone in the Treatment of Ventricular Arrhythmia
Authors: Wang Zhenjie
Published: September 2023

Objective: To explore and analyze the clinical effect of small and medium doses of Betaloc combined withamiodarone in the treatment of ventricular arrhythmia. Methods: 60 patients with ventricular arrhythmia that were treated in the Department of Cardiology of our hospital from May 2018–May 2023 were selected for this study, and they were divided into a research group (n = 30) and a reference group (n = 30). The study group was treated with small doses of Betaloc and amiodarone, while the reference group was treated with conventional treatment. The total efficacy of medication, QRS interval, standard deviation of normal-to-normal (NN) intervals (SDNN), root mean square of successive differences between normal heartbeats (RMSSD), standard deviation of the average NN intervals (SDANN), and incidence of adverse reactions were compared between the groups. Results: The effectiveness of medication in the study group was significantly higher than that in the reference group (P < 0.05). Besides, there was no statistically significant difference (P > 0.05) in the QRS interval and SDNN between the two groups before treatment. After treatment, the QRS interval and SDNN of the study group were significantly lower than those of the reference group (P < 0.05). Before treatment, there was no significant difference in RMSSD and SDANN between groups (P > 0.05). After treatment, RMSSD and SDANN in the study group were significantly better than those in the reference group (P < 0.05), and the difference was statisticallysignificant. The incidence of adverse reactions in the study group was significantly lower than that in the reference group (P < 0.05), and the difference was statistically significant. Conclusion: Small doses of Betoprolol and amiodarone is more effective in the treatment of ventricular arrhythmia, which has the value of popularization and application.
Research on the Effect of Humanistic Nursing Care on Elderly Type 2 Diabetes Mellitus Patients
Authors: Liang Hui
Published: September 2023

Objective: To explore and analyze the effect of humanistic nursing care on elderly type 2 diabetes patients. Methods: 100 elderly patients with type 2 diabetes who were treated in our hospital from May 2021–May 2023 were selected for this study. The patients were divided into an experimental group and a reference group by flipping a coin, with 50 cases in each group. The experimental group received humanistic nursing care, while the reference group received routine nursing care. The blood glucose level, compliance and nursing satisfaction were compared between the two groups. Results: Before the intervention, there was no statistically significant difference between the groups in pre-meal blood glucose, blood glucose 2 hours after eating, and glycosylated hemoglobin (P > 0.05). After the intervention, pre-meal blood glucose, blood glucose 2 hours after eating, and glycosylated hemoglobin in the humanities group were significantly better than those in the reference group (P < 0.05). Besides, before the intervention, there was no statistically significant difference in compliance with diet, medication, examination, and exercise between the groups (P > 0.05). After the intervention, the compliance with diet, medication, examination, and exercise in the experimental group was significantly better than that of the reference group (P < 0.05). The patients in the experimental group were significantly more satisfied with the nursing care received than the reference group (P < 0.05). Conclusion: Humanistic nursing care can reduce blood sugar in elderly patients with type 2 diabetes, strengthen treatment compliance, and improve satisfaction.
Application Effect of Chinese Medicine Rehabilitation in the Treatment of Adolescent Ankle Sports Injuries
Authors: Dong Ming
Published: September 2023

Objective: To analyze the clinical effect of traditional Chinese medicine rehabilitation in treating adolescentankle sports injuries. Methods: From December 2020 to December 2022, adolescent patients with ankle joint sports injuries admitted to our hospital were selected as observation objects, and 67 patients were divided into a control group (n = 33, routine rehabilitation treatment) and an experimental group (n = 34, traditional Chinese medicine rehabilitation treatment) according to the computer grouping method. Compare the treatment results. Results: (i) The treatment received in the experimental group had an efficacy of 94.11%, which was higher than that of the control group (75.75%), and statistical significance was established (P < 0.05). (ii) Before treatment, there was no difference in ankle joint pain, ankle joint activity, and ankle joint function scores between the control group and the experimental group (P > 0.05); after treatment, the ankle joint pain, ankle joint activity, and ankle joint function scores in the experimental group were significantly higher than those in the control group (P < 0.05). (iii) The experimental group had higher scores on physiological function, physiological function, physical pain, general health status, energy, social function, emotional function, and mental health compared to the control group (P < 0.05). Conclusion: Traditional Chinese medicine rehabilitation is effective in treating ankle injuries caused by sports in adolescents and improve their quality of life. Therefore, it should be popularized.
Survey on the Status Quo of Emergency Response Capabilities of Public Health Emergencies in Grassroots Disease Control Institutions in a Certain Area
Authors: Jiang Zhaohua
Published: September 2023

Objective: To survey and study the emergency response capabilities of grassroots disease control institutions in a certain area for public health emergencies, and to put forward suggestions for rectification. Methods: The study was carried out from March 2022 to March 2023. Field surveys, questionnaire surveys, and interviews were used to investigate and analyze the emergency response capabilities of public health emergencies in 5 county Centers for Disease Control and Prevention (CDCs) in the region. Results: Through the survey, it was found that the professional level of the existing emergency team personnel of the grassroots disease control institutions in this region needs to be improved. There was an overall lack of emergency plans, and the compliance rate of the equipment, inspection, and testing items was low. The health emergency system of the CDCs in the region and the ability of the talent team need to be further improved. Conclusion: The emergency response capacity of grassroots disease control institutions in this region needs to be improved. For this reason, government departments need to increase investment and strengthen the construction of talent teams and hardware settings, and grassroots disease control institutions need to strengthen the construction of the public health emergency system to improve the ability to respond to public health emergencies.
Hipervigilancia y fake news:
Authors: Postigo Vanuza Monteiro Campos , Andrade Regina Glória Nunes
Published: September 2023

O falseamento de realidade assume proporções desmedidas e virais na era da comunicação e do compartilhamento com consequências nocivas para a sociedade. O negacionismo e as chamadas fake news não são inéditos em nossa cultura, mas encontram nas redes sociais de relacionamento e na internet uma arquitetura e uma lógica de funcionamento que potencializam e facilitam sua disseminação. Vamos explorar como na atual cultura hiperconecada da hipervigilância encontramos ecos da ficção distópica de George Orwell, 1984, no que concerne ao manejo e falsificação de narrativas a serviço de ideologias e interesses próprios. No livro 1984 o autor apresenta uma sociedade dominada por um estado totalitário representado pelo Grande Irmão, que vigiava seus cidadãos através da “teletela” e fabricava as suas próprias notícias através do Ministério da Verdade, enquanto que na sociedade hodierna digital os próprios usuários conectados se habilitam a portar voluntariamente suas “teletelas” nas quais se ofertam ao controle e através das quais acessam a possibilidade de cada indivíduo fabricar e disseminar as suas próprias verdades e narrativas. Desenvolveremos uma pesquisa teórica para investigar como os dispositivos tecnoculturais da era da informação e da hipervigilância favorecem a produção de fake news e falseamentos da realidade, que ensejam e sustentam os desmentidos e o negacionismo contemporâneos. Observamos em nosso estudo como, em uma sociedade infômana, a intervigilância é um elemento naturalizado e mesmo desejado nas práticas comunicacionais e de sociabilidade, ensejando a oferta e adesão dos usuários das redes a um controle social superpanóptico. A vida compartilhada em redes virtuais fomenta a produção de dados e informações nos âmbitos individuais, sociais, profissionais, políticos, econômicos, na sociedade datificada às quais os indivíduos voluntariamente aderem. Essa datificação e produção de informação não exigem veracidade ou verificação de seu conteúdo, criando um campo propício a falseamentos de verdade e fake news.

Palavras-chave: hipervigilância, fake news, teletela, negacionismo
Effect of different processing methods on functional and physiochemical properties of turmeric (Curcuma longa Linn.) rhizome Var. Kapurkot Haledo-1
Authors: Dhami Govinda , Paudel Satish , Sapkota Saroj
Published: September 2023

This study was conducted to evaluate the impact of different processing methods on the functional and phytochemical properties of turmeric rhizomes. The experiment consisted of four treatments: Treatment 1 involved oven-drying the turmeric powder, Treatment 2 involved blanching followed by oven-drying, Treatment 3 involved cooking followed by oven-drying, and Treatment 4 involved sun-drying. Each treatment was replicated four times. The major findings of the study revealed that sun-drying (68.50%) and blanching/oven-drying (66.50%) positively influenced the dispersibility of turmeric powder. Blanching/oven-drying (0.32 g/ml) and cooking/oven-drying (0.30 g/ml) significantly improved the bulk density of turmeric powder (p<0.001), with no significant difference observed between these two treatments. The water absorption capacity of the turmeric powders ranged from 3.35 to 5.35 g/ml, with the sun-dried sample displaying the lowest capacity and the cooked/oven-dried sample demonstrating the highest capacity. Similarly, sun-dried powder exhibited the lowest swelling power and solubility, while heat treatment resulted in a substantial increase in both of these parameters. Additionally, the curcumin content was found to be highest in the cooked/oven-dried (3.11%) and sun-dried (2.99%) turmeric powder. In conclusion, this study suggests that blanching and cooking methods have wide applicability in the food industry to enhance the bulkiness of turmeric powder for appropriate packaging and handling. Moreover, these methods contribute to the characteristic flavor and aroma of turmeric. The findings emphasize the importance of considering different processing techniques for optimizing the functional and phytochemical properties of turmeric, thus enabling its effective utilization in various food applications.
Profitability and prospects of crop insurance of some selected crops in Kishoreganj district of Bangladesh
Authors: Prome Nowshin Tabassom , Rahman Mohammad Ataur , Begum Ratna , Ahamed Md. Shishir
Published: September 2023

Crop insurance is an essential tool for managing risk in agriculture. The primary goal of this study was to investigate how farmers felt about crop insurance and their willingness to pay for it. . The study was conducted to profile the socioeconomic characteristics, measure the profitability of crops, assess farmer’s willingness to pay crop insurance, and determine the factors that influence willingness to pay (WTP). A total of 107 farmers were chosen at random from Kishoreganj district in Bangladesh. The data were collected through a field survey using a semi-structured interview schedule. Karl Pearson’s correlation coefficient method was used. The study found that the majority of farmers have only had primary education or less. About one-third of the respondents could make savings of ten to twenty thousand taka each year. The most profitable crops were vegetables, jute, and wheat. Rice’s profitability, however, was hardly positive. Factors such as age, education, occupation, net income, and cultivable area have a positive correlation with the WTP for crop insurance for all crops except rice. However, the uptake of crop insurance is still relatively low in Bangladesh, and more efforts are needed to increase awareness and promote the benefits of crop insurance among farmers.