bluuebunny/crossref_metadata_2025 huggingface dataset:
RED Is “Happy” but Also “Gloomy”: The Influence of Young People on Color Preference and Emotional Changes During the COVID-19 Pandemic
Authors: Wang Ching-Yi , Ku Hsiu-Yu , Lin Chang-Yi
Published: November 2024

The COVID-19 pandemic has significantly impacted human psychological and emotional states, influencing behaviors, including color preferences. This study aimed to explore how the pandemic affected people’s color preferences and emotional responses, shedding light on the broader implications for psychological well-being. A total of 231 participants were divided into two groups based on the depth to which they were affected by the pandemic, considering factors such as personality, family, friends, work/lessons, relationships, and consumption. The findings revealed four key results: (1) participants’ preference for cooler colors such as blue and green increased, reflecting a need for calmness and stability during heightened stress, while their preference for warm colors decreased. (2) Personal consumption was identified as the most severely impacted area. (3) The pandemic reduced people’s overall preference for warm colors. (4) The pandemic triggered strong negative and contradictory emotions. These results highlight the significant shift towards cooler colors, which are associated with calmness, and suggest important applications in design, marketing, and mental health initiatives. Understanding the psychological effects of the pandemic on color preferences provides valuable insights across multiple fields and emphasizes the importance of adapting to the reshaped aspects of human behavior in the face of future challenges.
Inhalation corticosteroids for COVID-19 – a real world data analysis on guideline adherence
Authors: van Egeraat Jasper WA , Kuijpers Ton , Burgers Jako , van Os Hendrikus , Chavannes Niels H , Bonten Tobias N
Published: November 2024

Background

The recommendation to consider prescribing inhalation corticosteroids to a subgroup of vulnerable COVID-19 patients was added to the Dutch medical guideline on November 11, 2021, and was also adopted by other countries during the pandemic.

Aim

To evaluate the adherence of general practitioners to this guideline, and whether real-world data quality is sufficient to study the effect of revised guidelines on prescribing behaviour.

Design & setting

A retrospective cohort study using Dutch primary care data from the Extramural LUMC Academic Network database, containing patient data of 129 general practices in the Leiden – The Hague area.

Method

We performed an interrupted time series analysis to measure the effect of the new guideline on the prescription rate of ICS, accounting for general trend and seasonal fluctuations.

Results

Between July 1, 2020 to August 1, 2022, 131,482 patients had 164,098 COVID-19 consultations. During this period, 1,709 patients received 2094 ICS prescriptions for COVID-19. After the guideline update, there was an instantaneous decrease in prescription rate (IRR 0.47, 95% CI 0.32-0.69). Prescription rate in the subgroup of vulnerable patients did not change significantly (IRR 0.93, 95% CI 0.66-1.32), while less vulnerable patients were significantly prescribed less (IRR 0.29, 95% CI 0.14-0.59).

Conclusion

The revision to COVID-19 guidelines had significant impact on general practitioners’ prescription behaviour soon after publication: prescription rate remained constant for vulnerable patients, while less vulnerable patient were significantly prescribed less often. Using electronic health records it is feasible to assess changes in guideline adherence using interrupted time series.
Higher Serum Alkaline Phosphatase is Risk for Death and Fracture
Authors: Maruyama Yukio , Nakashima Akio , Abe Masanori , Hanafusa Norio , Nakai Shigeru , Yokoo Takashi
Published: November 2024

Background:

Monitoring of serum alkaline phosphatase (ALP) is recommended in the management of chronic kidney disease (CKD)-mineral bone disorder (MBD) because of associations with poor outcome among dialysis patients. However, such associations may have changed with several advances in the management of CKD-MBD over the last decade.

Methods:

Baseline data for 241,670 dialysis patients (mean age, 69 ± 12 years; male, 65.9%; median dialysis duration, 68 months) were extracted from a nationwide dialysis registry in Japan at the end of 2019. Outcomes, including all-cause and cardiovascular (CV) mortality and hip fracture, were evaluated using the registry at the end of 2020 and 2021. All-cause mortality was assessed using Cox regression analysis, whereas CV mortality and new hip fracture were assessed using competing-risks regression analysis. Multiple imputation for missing values was performed.

Results:

Within the 2-year study period, a total of 40,449 patients (16.7%) died, including 13,562 (5.6%) CV deaths. Of the 168,836 patients with no history of hip fracture at the end of 2019, 4,136 (2.4%) suffered hip fracture within 2 years. Higher serum ALP was independently associated with higher all-cause and CV mortality and new hip fracture, but the association with CV mortality was marginal (hazard ratio [HR] 1.21, 95% confidence interval [CI] 1.18-1.24; sub-HR [SHR] 1.07, 95%CI 1.03-1.12; and SHR 1.28, 95%CI 1.19-1.38, respectively). There is a linier association between serum ALP and all-cause mortality among the lower- parathyroid hormone (PTH) group, whereas lower serum ALP tended to have higher all-cause mortality than intermediate serum ALP among patients in the higher-PTH group.

Conclusions:

Higher serum ALP was independently and linearly associated with higher all-cause and CV mortality and new hip fracture in Japanese dialysis patients. Higher serum ALP and higher intact PTH were synergistic in increasing all-cause and CV mortality but not with new hip fracture.
Ubeyd Dede’nin ve Kur’ân Sûrelerinin İsimlerine Dair Farsça Manzum Eseri
Authors: Söylemez İdris
Published: November 2024

Kur’ân-ı Kerim, Hz. Muhammed’e Cebrail tarafından vahiy yoluyla getirilen kutsal bir metin olup İslâm dinin temel kaynağıdır. Bundan dolayı ilk zamandan itibaren Müslümanlar tarafından anlaşılmaya çalışılmış ve üzerinde de pek çok çalışma yapılmıştır. Kur’an-ı Kerim’in bizzat anlaşılması üzerine yapılan çalışmaların yanı sıra onun anlaşılmasını daha da kolaylaştıracak çalışmalar Kur’an-ı Kerim’in dili, gramatik yapısı, içeriği, surelere taksim edilişi ve Mushaf biçimine geliş tarihi hakkında başta tefsirciler olmak üzere farklı alanlarda ilim adamları tarafından her asır değişik çalışmalar yapılmıştır. Kuşkusuz Kur’an-ı Kerim aynı zamanda edebiyatçıların da ilgi alanında olmuş, onlar tarafından da bu kutsal metin üzerinde çok fazla sayıda çalışma yapılmıştır. Edebiyatçılar bu kutsal metnin hem içeriğine hem de biçimine ilgi duymuşlardır. Edebiyat mahfillerinde eser verenler Kur’an-ı Kerimi eserlerine bütünüyle ya da iktibas ve telmih sanatları bağlamında temel kaynak olarak başvurmuşlardır. Onların ilgi duyduğu konulardan biri de hiç şüphesiz surelerinin isimleri hususunda olmuştur. Hatta bu isimlerle ilgili müstakil çalışmalar da kaleme almışlardır. Bu eserler, önemli oranda manzum olarak telif edilmişlerdir. Bunlardan birisi de çalışmamıza konu edindiğimiz Ubeyd Dede tarafından kaleme alınmış olan Farsça manzum eserdir. Bu eser, sahanın önemli çalışmalarından biri olarak tebellür etmektedir. Hal böyle olunca elinizdeki makalenin konusu olmuştur. Ancak Ubeyd Dede’nin eserine geçmezden önce manzum sure geleneği hakkında bilgi vermenin gerekli olduğu düşünülmüş ve Anadolu sahasında bu konuya dair eserler hakkında kısaca bilgi verilmiştir. Akabinde de Ubeyd Dede’nin “Manzum Suver-i Kuran”adlı eseri biçimsel özellikleri ve muhtevası bakımından detaylı bir şekilde ele alınmıştır.”Çalışmanın sonuna da eserin Arap alfabesi ile orijinal metni, latinize edilmiş olan çeviri metin ile eserin tercümesi bir arada verilmiştir.
İslam Medeniyetinin İlk Toplumsal Normlarının Oluşması Bağlamında Hz. Peygamber’in Biatleri
Authors: Kıranşal Abdulaziz
Published: November 2024

İslam dinin temel esasları doğrultusunda yeni bir toplum oluşturan Hz. Peygamber, bu toplumun oluşum sürecinde muhataplarından çeşitli zamanlarda biat almıştır. Biat, Hz. Peygamber’i hem dini hem de siyasi bir otorite olarak tanımak ve kesin itaat sözü vermek olarak anlam kazanmıştır. Hz. Peygamber, bu biatler vesilesiyle şirk ve asabiyet merkezli cahiliye anlayışına karşı tevhid, nübbüvvet ve ahiret inancını merkeze alan yeni bir paradigma oluşturmuştur. Bu paradigmaya dayalı yeni medeniyetin ilk toplumsal normları ise Hz. Peygamberin kimi zaman tek tek kimi zaman ise toplu halde aldığı biatlerin içerdiği maddelerde kendini göstermiştir. Zira Kur’an ayetlerinin büyük bir bölümünün henüz nazil olmadığı İslam’ın ilk yıllarında gerçekleşen biatlerdeki ana maddeler, Allah’a, Peygamber’e ve ahirete iman gibi inanç esaslarının yanında İslam medeniyetinin ana ilkelerini oluşturan ahlaki ve sosyal prensipleri de barındırmıştır. Bu anlamıyla Hz. Peygamber dönemi biat müessesesi bir yandan tevhid, nübüvvet ve ahiret merkezli yeni bir değerler sitemi üretirken bir yandan da toplumun bu değerler sistemine bağlı kalmasını sağlayacak hukukun temelini teşkil etmiştir. Çünkü İslam dinini kabul eden fertler Hz. Peygamber’e biat ederek, hırsızlık yapmamak, zina etmemek, çocuklarını öldürmemek, her şart ve durumda hakkı söyleyip gerçeği korumak, Müslüman kardeşlerine nasihat etmek ve samimi davranmak gibi konularda söz vermişlerdir. Böylece hem yeni oluşacak toplumun huzur, istikrar ve güvenliğini sağlayacak olan ana ilkeler belirlenmiş hem de İslam medeniyetinin ilk toplumsal normları oluşmaya başlamıştır.
Диффузия информационно-коммуникационных технологий в странах БРИКС
Authors: М.Г. Дубинина
Published: November 2024

В статье рассмотрены проблемы развития сектора ИКТ стран БРИКС на современном этапе, проанализирован уровень распространения цифровых технологий и место, занимаемое странами в мировых рейтингах информационного общества. Проанализирована динамика торговли ИКТ-товарами и услугами. Оценена диффузия интернета для этих стран с помощью логистической модели и модели Басса. Для выявления макроэкономических факторов, влияющих на скорость распространения интернета, построена пространственно-временная модель его диффузии по странам БРИКС.

The article examines the problems of development of the ICT sector of the BRICS countries at the present stage, analyzes the level of distribution of digital technologies and the place occupied by countries in world rankings of the information society. The dynamics of trade in ICT goods and services are analyzed. Internet diffusion for these countries was estimated using the logistic model and the Bass model. To identify macroeconomic factors influencing the speed of Internet diffusion, a space-time model of its diffusion across the BRICS countries was built. Keywords: digital technologies, information and communication technologies, ICT infrastructure, space-time model, Internet, digital development index
Демографические характеристики занятости в области информации и связи, в финансах и страховании в России
Authors: А.М. Нанавян
Published: November 2024

В работе проанализированы демографические аспекты занятости в сфере информации и связи и в финансах и страховании. В этих видах деятельности наименьшее значение среднего возраста занятых в России, но наблюдается рост значения этого показателя, особенно в финансах и страховании. Это связано как с сокращением численности лиц в возрасте 20–29 лет, так и с увеличением численности старших возрастных групп в составе занятых в рассматриваемых видах экономической деятельности.

The paper analyzes the demographic aspects of employment in the field of information and communications and in finance and insurance. In these types of activities, the average age of the employed in Russia is the lowest, but there is an increase in the value of this indicator, especially in finance and insurance. This is due both to a decrease in the number of people aged 20-29 years, and to an increase in the number of older age groups employed in the types of economic activities under consideration.
Sağlık Çalışanlarının Kolorektal Kanser Tarama Programına Yönelik Farkındalık ve Davranış Düzeyinin Değerlendirilmesi
Authors: Keskinkılıç Yağız Betül , Yalaza Metin
Published: November 2024

Amaç: Kolorektal kanserin erken dönemde tespit edilmesi için ulusal kolorektal kanser tarama programla-rı yürütülmektedir. Sağlık çalışanlarının tarama programlarına yönelik bilgi düzeyi toplumun programlara katılımını etkileyen önemli bir faktördür. Çalışmamızda hastanemizde çalışan hekim ve hekim dışı sağlık çalışanlarının kolorektal kanser tarama programına yönelik farkındalıkları ve davranış düzeyleri irdelenmiş-tir.
Materyal ve metod: Çalışmaya 366 sağlık çalışanı dahil edildi. “Kolorektal kanser tarama programına yönelik farkındalık ve davranış düzeyi” isimli anket uygulandı. Kolorektal kanser tarama programına yöne-lik bilgi düzeyleri, tarama testlerine katılım oranları, tarama programına yönelik doğru bilgiye sahip olma ve kolonoskopi yaptırma durumunu etkileyen faktörler araştırıldı. Kategorik değişkenler arasındaki ilişki-nin incelenmesinde ki kare testinden yararlanıldı.
Bulgular: Katılımcıların yaş ortalaması 41,05±8,69, %82,2’si 50 yaş altı, %73,2’si kadın idi. GGK tarama sıklığını %20,2 ve kolonoskopi tarama sıklığını %7,1 katılımcı doğru cevapladı. Katılımcıların %12,8’inde aile hikayesinin olduğu ve 50 yaş üzerinde kolonoskopi yaptırma oranının %12,3 olduğu izlendi. Kolorek-tal kanser ve tarama programına yönelik bilgi düzeyini etkileyen faktörler eğitim durumu ve meslek idi. Kolonoskopi yaptırma oranı 50 yaş ve üzerinde, hekimlerde, yüksek lisans mezunlarında ve aile hikayesi olanlarda daha yüksekti (p=0,027, p=0,002, p=0,003, p=0,003 sırasıyla)
Sonuç: Sağlık çalışanlarının ulusal kanser tarama programı hakkındaki bilgilerinin yetersiz ve katılım oran-larının düşük olduğu izlenmiştir. Eğitim düzeyinin artması ile tarama programına yönelik bilgi sahibi olma durumu ve taramaya katılım oranı artmaktadır. Yapılacak eğitim ve tanıtım faaliyetleri ile erken tanı için hastaların yönlendirilmesinde büyük önem taşıyan sağlık çalışanlarının farkındalığı artırılmalıdır.
ASSESSMENT OF HEAVY METAL LEVELS IN URBAN SOILS OF TRIPOLI, LIBYA, USING POLLUTION INDICES AND MULTIVARIATE ANALYSIS
Authors: Salem Mansour Awiadat , Alnaas Afiyah Salam , Alzarqa Ali Emran , Sharif Omer Ahmed , Nassar Yasser Fathi , Assad Mamdouh El Haj
Published: November 2024

This study analysed forty-six soil samples from the top 15 cm (6 in.) of urban soil in Tripoli, Libya for heavy metal contamination using atomic absorption spectrometry. The metals assessed included cadmium (Cd), lead (Pb), zinc (Zn), copper (Cu), nickel (Ni), cobalt (Co), iron (Fe), manganese (Mn) and chromium (Cr), with average concentrations of 3.94±1.93, 38.17±11.67, 170.94±62.68, 29.67±8.00, 19.70±8.75, 30.38±10.68, 27.444.52±8,739.15, 233.82±48.24, and 195.92±61.37 mg.kg-1.dwt (1.4E-4±7.0E-5, 1.35E-3±4.1E-4, 6.03E-3±2.21E-3, 1.05E-3±2.8E-4, 6.9E-4±3.1E-4 ,1.07E-3±3.8E-4, 0.97±3.08E-1, 8.25E-3±1.7E-3 and 6.91E-3±2.16E-3 oz.lb.-1.dwt), respectively. Most of these levels exceeded the permissible limits set by the World Health Organization and typical background values. Pollution indices suggested that the soil ranged from unpolluted to moderately polluted, with Cd, Co, Cr, and Zn being of particular concern. Cadmium was found to be the primary contributor to ecological risk, mainly from anthropogenic sources. Principal component analysis identified four key components: PC1 was dominated by Cd, Pb, and Zn with moderate contributions from Cu, related to human activities; PC2 was dominated by Fe and Cr; PC3 by Ni and Mn; and PC4 by Co and Cu, primarily from natural sources.
Victorine Meurent, modèle et artiste. Relecture d’un mythe de la décadence artistique
Authors: Dollet Adeline
Published: November 2024

Adolphe Tabarant, journaliste et critique d’art, a publié en 1931 et 1947 deux ouvrages qui constituent une source de premier ordre dans l’étude de l’œuvre et de la vie du peintre Édouard Manet. En 2023, la Morgan Library and Museum de New York a acquis une photocopie d’un manuscrit inédit et non publié de Tabarant. Ce manuscrit intitulé « Celle qui fut l’Olympia de Manet » se présente comme un récit biographie de Victorine Meurent, modèle préféré de Manet pour qui elle a posé entre 1862 et 1872. En rapport avec le mémoire de master consacrée à Meurent, l’objectif de cet article est d’évaluer certains éléments du manuscrit qui permettent d’établir sa valeur historique dans l’élaboration du mythe du modèle décadent, associé à la figure de Meurent.
The time factor and the allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia
Authors: Parovichnikova E. N. , Kuzmina L. A. , Vasilyeva V. A. , Pokrovskaya O. S. , Drokov M. Yu. , Lukyanova I. A. , Fidarova Z. T. , Gaponova T. V. , Troitskaya V. V.
Published: November 2024

Introduction. The current overall effectiveness of acute myeloid leukemia (AML) treatment is largely ensured by the integration of transplantation technologies, but not all patients who are indicated to undergo transplantation of allogeneic hematopoietic stem cells (allo-HSCT) can reach this stage.

Aim: to analyze the time and volume of the implementation of allo-HSCT in patients with AML in the first complete remission (1CR).

Materials and methods. Between January 2020 and December 2023, 477 AML patients from 43 different regions of the Russian Federation were referred to the NMRC for Hematology for the possibility of performing allo-HSCT. In this cohort of patients, the following time parameters were analyzed: days from diagnosis of AML to primary treatment at the transplant center, from primary treatment to search for a donor (related or non-related), from diagnosis of AML to allo-HSCT, from the achievement of 1CR to allo-HSCT.

Results. 175 (36.7 %) patients, agreed upon by the Transplant Commission, were selected to undergo allo-HSCT. Of these, only 163 patients, who had allo-HSCT performed before January 2024, were included in further analysis. It was not possible to implement allo-HSCT in the other 236 agreed upon cases due to the following reasons: refusal of the patient — 110 (46.6 %), relapse — 48 (20.3 %) patients, death — 23 (9.7 %) patients. Median time from 1CR to allo-HSCT was 6.8 (0.3– 26) months for all patients: for a related fully compatible donor 5.8 (0.5–26.0) months, for a haploid donor — 6.1 (0.3–23.5) months, in case of non-related — 8.0 (0.6–8.6) months. In 5 years, the NMRC for Hematology managed to reduce the time to the general allo-HSCT in 1CR for patients with AML from 6.5 months in 2018 to 5.8 months in 2023. Also, under the current “AML-21” protocol, the time from 1CR to allo-HSCT in patients included in the multicenter study was minimized to — 4.8 (0.33–11.0) months, and for AML patients from the poor prognosis group — 3.4 (0.33–8.0 months).

Conclusion. In addition to achieving full, optimally — MDR-negative remission, the absence of severe concomitant pathology, and the presence of a donor, the time factor must also be considered. In order to cure more AML patients, it is necessary to bring the implementation of allo-HSCT to the earliest possible date after achieving 1CR.
Effect of glucocerebrosidase on human bone marrow multipotent mesenchymal stromal
Authors: Mamonov V. E. , Sadovskaya A. V. , Petinati N. A. , Shipounova I. N. , Dorofeeva A. I. , Drize N. I. , Lukina E. A.
Published: November 2024

Introduction. During enzyme replacement therapy in patients with Gaucher disease (GD) with recombinant glucocerebrosidase (GCase), regression of bone manifestations is possible, but with prolonged therapy osteonecrosis may occur. These changes may be due to impaired differentiation of multipotent mesenchymal stromal cells (MSCs).

Aim: to study changes in the MSCs of healthy donors and a patient with GD when cultured in the presence of GCase.

Material and methods. MSCs were isolated from the bone marrow of 17 healthy donors and a female patient with GD by a standard method and cultured in the presence of various concentrations of GCase after the second passage from 2 to 7 weeks. Cell proliferation and the ability to differentiate were analyzed, including after induction. The assessment was carried out by differential staining, elution, and expression of differentiation marker genes by real-time PCR.

Results. Low concentrations of recombinant GCase (0.25–1.5 U/ml) did not affect the proliferative activity of MSCs. Prolonged cultivation of MSCs in the presence of low doses of GCase led to a change in the differentiation potential of these cells in the direction of adipogenesis. Concentrations of GCase of 3–5 U/ml inhibited the proliferation of MSCs and caused significant changes in cell differentiation. High doses of the enzyme (7–10 U/ml) had a cytotoxic effect and led to cell death within one passage. The proliferative and differentiation potential of the MSCs of a patient with GD differed significantly from the cells of healthy donors in all the parameters studied.

Conclusion. The cultivation of donor MSCs in the presence of recombinant GCase alters the proliferation and differentiation potential of these cells. These changes depend on the dose of the enzyme in the medium and the duration of cultivation.
Editorial
Authors: Aguirre Chávez Felipe
Published: November 2024

En esta vigesimoquinta edición de EDUCA UMCH, nos complace presentar una colección de ocho artículos que exploran a profundidad algunas de las problemáticas más urgentes de la educación contemporánea. Estos trabajos, fruto de investigaciones rigurosas, ofrecen análisis críticos y propuestas innovadoras, con el objetivo de enriquecer el debate académico y orientar hacia la mejora continua de las prácticas educativas.
Diakrytyczne cechy eschatologii pentekostalnej
Authors: Ern Agata
Published: November 2024

Artykuł poświęcony jest eschatologii pentekostalnej, wyróżniającej się na tle tradycyjnych koncepcji eschatologicznych. Pierwsza część artykułu porusza aspekt genezy eschatologii pentekostalnej i to, jak rozumiana jest eschatologia w ewangelikalizmie. Kolejne części pracy traktują o założeniach pentekostalizmu i związanej z nim eschatologii. Postawiono pytania o paruzję i w jaki sposób należy się do niej przygotować w świetle eschatologii pentekostalnej. Eschatologia zielonoświątkowa kładzie akcent na osobę Ducha Świętego jako inspiratora procesu nawrócenia człowieka i jego przygotowania na Boży sąd. Jedynie Duch Święty uzdalnia człowieka, by ten mógł współpracować z Bogiem nad realizacją scenariusza eschatologicznego. Na koniec zostaje postawione pytanie, czy eschatologia została już zrealizowana. Teologia pentekostalna twierdzi, że eschatologia jest proceduralna, a może być zrealizowana jedynie w paruzji.
Genoa and Barcelona. Urban transformation and participation
Authors: Canessa Nicola Valentino
Published: November 2024

In 1992 the cities of Barcelona and Genoa both began their recent transformation journey, the former with the Olympics and the latter with the Colombians. While the former capitalised on its transformations, beginning an extensive path of both public and private investments, the latter focused on processes related to major events, happenings or funding (G8, Genoa Capital of Culture, Morandi Viaduct collapse, the national resilience and recovery plan (NRRP), etc.). It is interesting to note that, to date, in both cities, citizen participation or activation largely depends on how much the city seeks consensus on transformation operations more than on design choices by adopting a top-down approach, which is similarly configured in all large and medium-sized European cities. They hardly give space or importance to bottom-up processes except when synergistic to an already planned strategy.
Evaluation criteria for a systemic approach to flood risk management: stakeholders’ perspectives
Authors: Vanelli Francesca , Lavagna Monica , Minifie Paul
Published: November 2024

Flood risk management authorities rely on structural engineering measures centralised at the spatial and governance levels. These are mainly evaluated based on damage reduction without considering social, economic and environmental criteria. The research proposes an evaluative and procedural methodology to support the choice of spatially distributed measures. After illustrating the research project and the applied methodology, the paper focuses on the first methodological step, which involves identifying multi-scalar and multidisciplinary evaluative criteria through a systematic literature review and interviews. The paper concludes by presenting the criteria, reflecting on the topic and the subsequent developments of the research.
Role of IVC Indices to Determine the Volume Status in Edematous Nephrotic Syndrome Children
Authors: Khondaker Dr. Tarannum , Hasnat Dr. Mohammad Abu , Afroz Dr. Shireen , Chaudhury Dr. Gulshan Nigar , Ferdaus Dr. Tahmina , Yesmin Dr. Farhana , Ferdous Dr. Jannatul , Saha Dr. Keya Rani
Published: November 2024

Background: Ultrasonography is a widely used tool for assessment of volume status of nephrotic syndrome in children. Objective: This study aims to assess the efficacy of sonographic assessment of inferior vena cava indices to detect this volume status. Methodology: This cross-sectional study involved around 50 children of steroid-sensitive Nephrotic Syndrome relapse, attending the department of Pediatric Nephrology of Bangladesh Shishu Hospital and Institute. Results: About 64% reported non-hypovolemic status; 36% patients had hypovolemia on the basis of urinary indices. The mean value of Fe Na was 0.24 ± 0.19 Umol/L in non-hypovolemic group and 0.14 ± 0.16 Umol/L in hypovolemic group. On the basis of sonographic assessment of IVC Collapsibility index, 80% were in non-hypovolemic group and 20% were in hypovolemic group. Based on IVC Aortic ratio, 66% belonged to non-hypovolemic patient and 34% in hypovolemic group. Statistically significant relationship was not found between different volume status by urinary indices and IVC collapsibility index (p=0.463) sensitivity and specificity of IVCCI in relation to urinary indices was 27.7%; 84.3% and positive prediction value was 50%. Conclusion: The majority of patients with nephrotic syndrome followed non-hypovolemic status. IVC: Aortic ratio can be better tool for volume assessment in nephrotic syndrome children. However, large scale study should be executed to confirm the efficacy of this tool.
Dermatite e Doenças Sistêmicas: Relações Clínicas e Diagnóstico Diferencial
Authors: Aparecido Irrazabal Leandro , Moreira Menezes Maria Eduarda , Speth Eichner Nathan , De Carvalho do Nascimento Castro Anna Paulla , Pereira Nicoly , De Moraes Oliveira Dávila , de Souza Silva Barbosa Luiz Philipe , Dos Reis Vial Eduarda , Bordignon Flores Alexandra Maria , De Assis Rocha Lima Felipe , De Medeiros Oliveira Paulo Victor , Lucena Santos Priscylla , Zacarias Queiroz de Barros Braga Guilherme
Published: November 2024

Introdução: A dermatite é uma condição inflamatória da pele que pode se manifestar através de erupções cutâneas, vermelhidão, coceira e descamação. Embora frequentemente considerada uma condição isolada da pele, pode estar intimamente relacionada a diversas doenças sistêmicas. Portanto, é fundamental adotar uma abordagem abrangente, que considere não apenas os sintomas dermatológicos, mas também o contexto sistêmico do paciente. Objetivo: : Explorar as conexões entre manifestações dermatológicas e condições sistêmicas subjacentes Metodologia:  Foram utilizadas as bases de dados Cochrane, Scielo e Pubmed, buscando artigos publicados entre os anos de 2019 e 2024, nos idiomas Português ou Inglês. Considerações Finais: A dermatite está frequentemente relacionada a diversas doenças sistêmicas, por isso, requer uma abordagem clínica abrangente, visando um diagnóstico diferencial adequado. Nesse contexto, é essencial considerar as manifestações cutâneas como possíveis sinais de condições subjacentes, tais como doenças autoimunes, infecciosas, endocrinológicas e hematológicas. Dessa forma, uma gestão eficaz depende da interação entre diagnóstico preciso e estratégias terapêuticas adaptadas a cada caso.
SÍNDROME DE BURNOUT EM PROFISSIONAIS DA SAÚDE E A GESTÃO HOSPITALAR COMO FERRAMENTA DE PREVENÇÃO
Authors: Xavier Oliveira Káryta Lorrane , Ferreira Laura Fábia , Pereira de Siqueira Amanda , Santos Queiroz Andressa Karoline , Marques Miranda Bruna Isabel , César de Oliveira Grazielly , Lopes Silva Guilherme Ramos , Pereira Ataíde João Marcus , Francisco Leticia Suellen , Xavier Oliveira Karla fernanda , Tavares de Melo Pedro Paulo , Amaral Rhaygner Dhieggo
Published: November 2024

Síndrome de Burnout é uma enfermidade emocional que apresenta sintomas como: exaustão extrema, estresse e declínio físico. A etiologia da doença é justamente o excesso de trabalho. Esse estudo trata-se de uma revisão de literatura de caráter narrativo, na qual foram incluídos 10 artigos. A análise do recente trabalho interessou-se na pesquisa do índice dessa patologia na sociedade médica, nos profissionais da enfermagem e trabalhadores farmacêuticos. A doença é uma grande problemática da saúde, visto que está diretamente ligada na conduta e individualidade do trabalhador, estes sintomas têm sido notificados em todas as especialidades médicas, sendo necessário uma melhor interatividade dos profissionais, autonomia e preparo. Portanto, vale salientar que é necessário o acompanhamento e proteção psicológica às equipes de saúde, ressaltando também, melhoria nas relações de trabalho no eixo empregador-empregado.
The Role of Neuromodulators and Deep Brain Stimulation (DBS) in the Treatment of Refractory Bipolar Disorder
Authors: D’ Ricolli Rebouças Rocha Raisa , Felício de Oliveira Samuel , Pereira Procópio Daniela , Ferreira Saddi Isabela , Steven Janse Silva Rayner , Christye Faria Neves Lailla , Siqueira de Oliveira Faria Monique , Silveira Leão Bruno , Maísa de Melo Fernanda , Abreu Forti Rumeningg , Cipriano Vanini Tupinambá de Oliveira Camille , Trigueiro e Silva Álvaro
Published: November 2024

Introduction: Refractory bipolar disorder is a complex psychiatric condition characterized by persistent manic and depressive episodes that do not respond adequately to conventional treatments, such as mood-stabilizing medications and antidepressants. This condition results in severe functional impairment, with a significant impact on patients' quality of life. Objective: To evaluate the role of neuromodulators and deep brain stimulation in the treatment of refractory bipolar disorder, analyzing their efficacy, mechanisms of action, and safety based on recent studies. Methodology: The research followed the PRISMA checklist guidelines for systematic reviews. Searches were performed in the PubMed, Scielo, and Web of Science databases, using the descriptors "refractory bipolar disorder", "deep brain stimulation", "neuromodulators", "treatment", and "therapeutic effects". The selection of articles was restricted to the last ten years. Inclusion criteria were: clinical studies on the use of DBS in refractory bipolar disorder, research investigating neuromodulators as additional therapies, and articles published in English, Portuguese or Spanish. Studies with small sample sizes, non-systematic reviews and articles that did not present relevant data on the therapeutic effects of these interventions were excluded. Results: The results indicated that both DBS and neuromodulators have shown to be promising therapies in the treatment of refractory bipolar disorder. DBS, especially when targeting the nucleus accumbens and other areas involved in emotional regulation, has been shown to reduce symptoms of mania and depression in several clinical studies. Neuromodulators, such as those affecting the dopaminergic and serotonergic systems, have also shown efficacy in some patients, but with less consistent results. Conclusion: Both deep brain stimulation and neuromodulators have shown potential in the treatment of refractory bipolar disorder, showing improvements in symptom control in patients resistant to conventional treatments. However, more long-term clinical studies are needed to consolidate the evidence of their efficacy and safety, in addition to optimizing treatment protocols.
State of students’ health and physical fitness under the restrictions of martial law
Authors: Griban Grygoriy P. , Lyakhova Natalia A. , Sirenko Romana R. , Terentieva Nataliia O. , Sahach Oksana M. , Salnykova Svitlana V. , Kanishcheva Oksana P.
Published: November 2024

Aim: To study the impact of martial law restrictions on the level of students’ health and physical fitness at higher educational institutions.
Materials and Methods: The research conducted in 2022-2024 involved 127 students (58 men, 69 women). Methods included analysis, synthesis and generalization of literary sources, express methodology for assessing physical health, testing of physical qualities, and methods of mathematical statistics.
Results: It has been established that martial law restrictions negatively impact students’ health and physical fitness. Over the two years of war, the level of physical health has significantly deteriorated by 1.8 for male students and by 2.0 for female students. The results of all physical fitness tests have also significantly deteriorated for both male and female students. Among the physical qualities, the most pronounced negative changes occurred in the endurance, strength, and flexibility indicators.
Conclusions: The research results show that students’ education under martial law in Ukraine, which takes place in various formats, is accompanied by significant emotional and intellectual intensity, extremely limited motor activity, and stressful situations. This negatively affects the health and physical fitness of today’s students. Future specialists’ poor health and low physical fitness can negatively impact their professional working capacity and cause various diseases.
Possibilities of integration of health promotion into the rehabilitation process
Authors: Brych Valeriya V. , Keretsman Angelika O. , Dub Mariana M.
Published: November 2024

Aim: The aim is to analyse and determine the possibilities of using health promotion tools and approaches at different levels of implementation of the rehabilitation process.
Materials and Methods: Published information sources on the organization of rehabilitation care and health promotion served as materials of the study. The methods of system analysis, structural and logical analysis, bibliosemantic and information-analytical methods were used during the research.
Conclusions: The implementation of the rehabilitation process at different levels requires different conditions, resources and the availability of specialists, which leads to different approaches to the integration of health promotion. On the basis of the defined categories of rehabilitation, it is possible to form a framework for the integration of health promotion into the rehabilitation process with the identification of potential tools and approaches. However, all levels require not only resources, but also appropriate professional training of specialists in the implementation of health promotion activities.
Simulative Investigation of the Influence of Different Abrasive Coating Structures in Double Face Grinding
Authors: Muthulingam Arunan , Uhlmann Eckart
Published: November 2024

The double face grinding process is a manufacturing process that is used when machining plane-parallel surfaces, for example during the production of bearing rings, wafers, seal and regulator disks. However, there are challenges when machining extremely hard and large components in terms of the required workpiece quality and cost-efficiency. Although the ecological disadvantages of the lapping process are present, it is often used to industrially machine such components. Therefore, the influence of different abrasive coating structures on the cooling lubricant flow was examined using Computational Fluid Dynamics (CFD) simulations. The results of the simulation studies are presented in this article. By choosing a suitable abrasive coating structure that ensures an even distribution of the cooling lubricant, the supply of cooling lubricant and chip removal during the grinding process can be improved. The results of the simulation studies show that radial grooves are unsuitable because the flow of cooling lubricant is not evenly distributed in the inner area of the grinding wheel. This can be optimized by selecting involute grooves. By improving the supply of cooling lubricant, the application range of the double face grinding process can be expanded and enables the environmentally friendly machining of extremely hard and large components with plane-parallel functional surfaces.
Pencegahan Fraud Akuntansi melalui Whistleblowing System dengan Peran Penerapan Perlindungan terhadap Whistleblower
Authors: Rahmahdita Lintang Nazhara , Widyaningsih Aristanti , Apandi Nelly Nur
Published: November 2024

Association of Certified Fraud Examiners (ACFE) menjelaskan bahwa fraud merupakan penyalahgunaan jabatan demi mendapatkan keuntungan untuk pribadi dengan menyalahgunakan sumber daya atau aset organisasi. Semua lapisan mulai dari golongan atas maupun golongan pegawai bawah memungkinkan adanya pelaku fraud. Kecurangan (fraud) adalah perbuatan tidak jujur yang berpotensi menimbulkan kerugian pada perusahaan atau karyawan atau orang lain, namun tidak sebatas hanya pada korupsi, pencurian uang, pencurian barang, penipuan, pemalsuan. Fraud merupakan fenomena global yang telah menciptakan dampak besar pada ekonomi dunia. Laporan Association of Certified Fraud Examiners (ACFE) 2024 menyatakan telah ditemukan 1.921 kasus dari 138 negara dan wilayah yang mengakibatkan kerugian global sebesar $31 miliar. Penelitian ini membahas pencegahan kecurangan (fraud) melalui whistleblowing system (WBS) dengan peran penerapan perlindungan terhadap whistleblower. Tujuan penelitian ini adalah untuk mengkaji penggunaan WBS dalam mencegah fraud serta menganalisis dampak perlindungan hukum terhadap efektivitas pelaporan. Penelitian menggunakan pendekatan kualitatif deskriptif dengan metode studi literatur. Data diambil dari 31 artikel ilmiah terindeks yang relevan dengan topik penelitian yang didapatkan melalui Google Scholar, Sinta, Scopus, Emerald, dan Springer. Hasil penelitian menunjukkan bahwa WBS berperan signifikan dalam deteksi dan pencegahan fraud yang harus didukung dengan jaminan perlindungan terhadap pelapor yang memadai. Rekomendasi mencakup kepastian perlindungan yang menyeluruh bagi whistleblower melalui kebijakan internal organisasi dengan anonimitas, proteksi dari ancaman, serta tindak lanjut yang jelas terhadap laporan yang diajukan.
Okul Öncesi Öğretmen Adaylarının Okul Dışı Öğrenme Faaliyetlerine Yönelik Tutumlarında Özyeterlik İnançlarının Rolü
Authors: Kanyılmaz Canlı Elif Süreyya
Published: November 2024

Bu çalışmada okul öncesi öğretmen adaylarının okul dışı öğrenme faaliyetlerine yönelik tutumlarının, okul dışı öğrenme faaliyetlerine yönelik özyeterlik inançları ve alt boyutları tarafından yordanma durumu incelenmiştir. Çalışmanın katılımcılarını 2023-2024 eğitim öğretim yılında bir kamu üniversitesinin okul öncesi öğretmenliği lisans programı 1., 2., 3. ve 4. sınıflarına devam eden 315 öğretmen adayı oluşturmaktadır. Araştırmanın verileri demografik bilgi formuna ek olarak Göloğlu-Demir ve Çetin (2021a) geliştirmiş oldukları “Okul Dışı Öğrenme Faaliyetlerine Yönelik Öğretmen Tutum Ölçeği” ve “Okul Dışı Öğrenme (ODÖ) Faaliyetlerine Yönelik Öğretmen Öz-Yeterlik İnançları Ölçeği” ile basılı form şeklinde toplanmış ve istatistiki analiz yöntemleriyle analiz edilmiştir. Analiz sonucunda ODÖ faaliyetlerine yönelik tutumun, ODÖ faaliyetlerine yönelik özyeterlik inançları tarafından ve özyeterliğin alt boyutları olan “Hazırlık”, “Uygulama ve Değerlendirme” ve “Öğrenmeyi Destekleme” özyeterlikleri tarafından yordandığı ancak “Bilgi ve Deneyim” özyeterliği tarafından yordanmadığı bulunmuştur. “Bilgi ve Deneyim” faktörünün bu şekilde sonuç vermesinin öğretmen adaylarının deneyime yönelik eksik hissetmesinden kaynaklı olduğu düşünülmektedir. Araştırmanın tüm bulguları göz önünde bulundurulduğunda okul öncesi eğitim programlarına okul dışı öğrenme ortam ve faaliyetlerine yönelik teorik ve uygulama içeren bir ders eklenmesi ve konuyla ilgili uygulamalı deneyimlerin artırılması önerilmektedir. Bu çalışma alanda bilgi ve deneyime sahip öğretmenlerle ve okul dışı öğrenme faaliyetlerine yönelik ders alan öğretmen adaylarıyla tekrarlanabilir.
Протестантизм в Японии: несостоявшееся обращение
Authors: Н.А. Мязин
Published: November 2024

Рассматривается развитие протестантизма в Японии от завершения самоизоляции страны до настоящего времени. Первоначально протестантизм активнее распространялся среди представителей самурайского сословия и образованных слоев населения. В довоенный период синтоизм стал частью государственной идеологии, христианство воспринималось как иностранная религия. После поражения Японии в войне была возвращена свобода вероисповедания. Христиане составляли около 1 % населения Японии, значительно большее распространение получили новые религии, созданные на основе буддизма. В статье уделено внимание взаимодействию христианства с японскими религиозными традициями: буддизмом и синтоизмом. Сделан вывод, что основная причина ограниченного принятия христианства — укорененность населения в буддистской культуре.

The article looks at the development of Protestantism in Japan from the end of the country’s self-isolation to the present day. Initially, Protestantism was more actively spread among representatives of the samurai class and the better educated strata of the population. In the pre-war period, Shintoism became part of the state ideology, and Christianity was perceived as a foreign religion. After Japan’s defeat in the war, freedom of religion was restored. Christians made up about 1 % of Japan’s population, but new religions based on Buddhism became much more widespread. The article focuses on the interaction of Christianity with Japanese religious traditions: Buddhism and Shintoism. It is concluded that the main cause of the limited adoption of Christianity was the population’s rootedness in Buddhist culture.
К творческой истории драматической поэмы С. А. Есенина «Пугачев»: текстология и поэтика ремарок в черновом автографе
Authors: А.А. Николаева
Published: November 2024

Цель статьи — проанализировать правку С. А. Есенина в черновом автографе драматической поэмы «Пугачев», связанную с работой поэта над ремарками. В есениноведении уже было доказано, что отказ от большей части ремарок, сохранившихся в черновике, обусловлен изменением жанра произведения. Однако исследователями не было отмечено, что поэт, задумывая произведение для постановки на сцене, уделял существенное внимание работе с ремарками. Автор статьи отмечает значительное количество вариантов одной ремарки в черновике (до четырех). Исследователь выделяет несколько типов правки внутри ремарок, связанных с указанием на детали происходящего, на действие героев на сцене и с работой над театральными приемами и эффектами. В результате делается вывод о том, что Есенин много работал не только над монологами и диалогами действующих лиц, но также и над ремарками, планируя использовать их как особые указания постановочной группе.

The purpose of the article is to analyze the editing of S. A. Yesenin in the draft autograph of the dramatic poem Pugachev connected with the poet’s work on stage directions. It has already been proved in Yesenin studies that rejection of most of the remarks preserved in the draft is due to a change in the poem’s genre. However, researchers have not taken into account that the poet, conceiving the work for staging on stage, paid considerable attention to the work with remarks. The author of the article notes a significant number of variants of such directions in the draft (up to four variants). The researcher identifies several types of proofreading options in these directions, pointing out the details of what is happening onstage, the movements of the actors and the theatrical techniques and effects. The conclusion is that Yesenin worked extensively not only on his characters’ monologs and dialog cues, but also on the stage directions and meant to use them as special instructions to a theatrical production team.
EVALUATING USER SATISFACTION AND EFFICIENCY OF E-REPORT SYSTEMS IN VOCATIONAL SCHOOLS: A PIECES FRAMEWORK ANALYSIS FROM TEACHER PERSPECTIVES
Authors: Bulan Vhivi
Published: November 2024

This study aims to evaluate the user satisfaction and efficiency of E-Rapor system by qualitative approach with PIECES framework on SMK Negeri 1 Kupang. The study focuses on uncovering the ice in the E-Rapor system. The research aims to identify strengths and areas for improvement in the system. Findings indicate that while the E-Rapor system significantly streamlines the process of student assessment and reporting, some performance issues, such as system slowdowns during peak usage, require optimization. Teachers typically feel that the system is easy to use, processes data quickly and is accurate. Nonetheless, changes in report structures and improvements in data protection such as the deployment of tougher encryptions or regular audits are needed. It is further recommend that technological support services be refined to serve user needs more effectively. The study findings suggest that while the system has had an overall positive effect on student learning, further revisions will be necessary for consistent use and optimal user satisfaction, ultimately informing clear guidance for future improvements throughthe PIECES framework.
THE IMPACT OF CREATIVE PROBLEM SOLVING MODEL ON STUDENT LEARNING OUTCOMES IN INFORMATION AND COMMUNICATION TECHNOLOGY
Authors: Babu Sarlota Uriana , Tantrisna Ellen , Nahak Roswita Lioba
Published: November 2024

This study aims to determine whether the implementation of the Creative Problem Solving (CPS) model has an effect on student learning outcomes in Information and Communication Technology (ICT) with study case at Public Junior High School N 7 Amabi Oefeto Timur. The methodology consisted in a quasi-experimental design study through the comparison of results under the pedagogy model CPS, taught to an experimental group and on traditional education, implemented on control group. Results showed that the experimental group had higher post-test scores than the control group in higher order thinking skills (problem-solving abilities) and understanding of ICT concepts. This was additionally seen with classroom observations where the students in the experimental group presented greater involvement, confidence in applying concepts of ICT to practical issues and collaboration with the peers. The first thing the CPS model did was start teaching students to think critically, accept that there are always multiple solutions and that together they can solve the problem. The findings indicated that the CPS model is an appropriate pedagogy for enhancing ICT learning performance, especially in resource-poor school contexts. The study suggests that the CPS model should be more prevalent in ICT education and should also be applied in online learning settings.