bluuebunny/crossref_metadata_2025 huggingface dataset:
Mid-term and long-term outcomes following heart transplantation with prolonged cold ischemia
Authors: Fomichev A. V. , Poptsov V. N. , Sirota D. A. , Zhulkov M. O. , Edemskiy A. G. , Protopopov А. V. , Kliver V. Y. , Skokova A. I. , Chernyavskiy A. M. , Khvan D. S. , Agayeva K. А.
Published: April 2023

Objective: comparative analysis of long-term outcomes following heart transplantation (HT) with prolonged and short cold ischemia.

Materials and methods. We analyzed the data of 29 orthotopic HT with >4 hours of cold ischemia. The transplant surgery was performed at Meshalkin National Medical Research Center between 2013 and the present time. Organs were obtained from donors from other regions. The control group consisted of 29 HTs with cold ischemia <4 hours, performed in the same period. The minimum distance between the transplant center and the donor base was about 250 km (Barnaul); the maximum distance was about 850 km (Krasnoyarsk). Recipient survival and postoperative peculiarities were analyzed.

Results. In-hospital survival in the prolonged cold ischemia group was 89.7% (n = 26) with 3 deaths (10.3%). In the second group (<240 min), in-hospital survival was 79.3% (n = 23) with 6 (20.7%) deaths. The Kaplan-Meier survival analysis showed no difference between the groups (Log-Rank Test, P 1/4 0.59). In addition, cold ischemia time did not increase the risk of graft rejection and the risk of transplant coronary artery disease (TCAD).

Conclusion. HT with cold ischemia >4 hours did not have worse outcomes than in short graft ischemia. This provides grounds for further accumulation of experience in the use of heart donors from remote locations.
Semen Semenovich Zimnitsky Scientific School: Pulmonology and Cardiology
Authors: Oslopov V. N. , Khasanov N. R. , Oslopova Yu. V. , Khazova E. V. , Mishanina Yu. S. , Oslopova D. V.
Published: April 2023

Semen Semenovich Zimnitsky was a great Russian internist, a participant in the Russo-Japanese War (1904-1905). He proved that soldiers wounded by pointed bullets are seriously injured they need annual leave. S. S. Zimnitsky can be considered one of the founders of battlefield internal medicine in Russia. In the work "Diseases of the pulmonary parenchyma and pleura", he described croupous pneumonia and "abdominal syndrome" with dry pleurisy. He also concludes that pulmonary tuberculosis is not a local disease but involves the whole organism, the state of defensive mechanisms of which determines both the disease performance and the results of immunological and biological tests.

The direction in internal medicine, created by S. S. Zimnitsky, was clearly reflected in following cardiology issues: heart failure, coronary artery disease, hypertension, bacterial endocarditis.
Herpetological diversity in forests of Portobelo National Park, Colón Biological Corridor, Panama
Authors: Fuentes Magallón Rogemif , Aschcroft Jesse , Barría Erick , Quintero-Arrieta Helio , Baules Alexis , Batista Abel , Zambrano Eduardo , Ponce Marcos
Published: April 2023

Panama has 229 species of amphibians and 280 species of reptiles, of which 72 (31.4%) are threatened according tonational legislation and 20 are endemic. The study area is of high ecological value and functions as a natural biologicalcorridor; however, it has very few sites that have been studied. For two years we sampled the area, registering 55 speciesof amphibians and 58 reptiles, including species with local conservation categories, new records of distribution, and anew species for science that will be described in a later work.
Cidade Matarazzo e suas transformações na paisagem urbana local da cidade de São Paulo/SP-Brasil: um estudo descritivo
Authors: Freitas Helmo Franklin Alves de , Quaresma Cristiano Capellani
Published: April 2023

Muitos projetos imobiliários geram conflitos entre a população local e o capital imobiliário. O Projeto Cidade Matarazzo na região central da cidade de São Paulo/SP-Brasil contava com intervenções arquitetônicas, como a construção de um boulevard e um espaço de convivência aberto a todos na área do antigo Hospital Matarazzo. Também previa a criação de uma passagem subterrânea para veículos em um trecho da Rua São Carlos do Pinhal, ação inviabilizada por um processo judicial movido por duas associações de moradores de bairro. Assim, o presente artigo objetiva descrever o empreendimento Cidade Matarazzo e o conflituoso projeto da construção da mencionada passagem subterrânea para veículos. Trata-se de um estudo descritivo de abordagem qualitativa, baseada em revisão bibliográfica, análise documental e estudo de caso. Os resultados permitem preencher uma lacuna na literatura e foram expressos em três subitens que abarcam as descrições do histórico de ocupação da área de implementação do empreendimento, das etapas de aprovação do projeto e dos detalhes do empreendimento e da construção do túnel na Rua São Carlos do Pinhal. Os resultados apresentados poderão subsidiar futuros trabalhos acadêmicos que foquem no entendimento do conflito mencionado, bem como que se dediquem ao melhor entendimento de conflitos sociais e ambientais que envolvem diferentes agentes de produção do espaço urbano.

PALAVRAS-CHAVE: Participação Popular. Conflito. NIMBY.
DEMOCRACIA E NEOCONTRATUALISMO DE JOHN RAWLS JUSTAPOSTAS AS PERSPECTIVAS DOS CONTRATUALISTAS MODERNOS HOBBES, LOCKE E ROUSSEAU
Authors: De Souza Delgado Joedson , Basso Ana Paula
Published: April 2023

Este trabalho apresenta uma análise de como a democracia e o neocontratualismo na teoria da justiça de John Rawls se conjuga com a teoria contratual clássica baseada na organização de conceitos e discursos de Thomas Hobbes, John Locke e Jean-Jacques Rousseau. A democracia representa a cultura e o pensamento político contemporâneo, quão emerge de expressões utilizadas em diferentes contextos, ainda vistas sob diferentes perspectivas, contribuindo para a diversidade de discursos. O neocontratualismo é uma variante da filosofia política liberal que faz da teoria do contrato a base racional da justiça.   como foi possível a clássica problemática da transição do estado de natureza para o estado de sociedade. A conclusão é que uma democracia perfeita é um ideal necessário para atrair participantes às demandas de uma ideia política.
KANT E A FUNDAMENTAÇÃO DOS DIREITOS HUMANOS NO PRÓPRIO HOMEM
Authors: Souza Monteiro Marco Antônio
Published: April 2023

Qual é a razão de ser dos direitos humanos? Partindo-se dessa pergunta e da premissa de que os direitos do homem demandam constante reflexão e cuidado, realizou-se breve estudo sobre conceitos do pensamento de Immanuel Kant referentes à ética e a moral humana, com objetivo de se encontrar um fundamento dos direitos humanos que se adeque ao pensamento contemporâneo. O trabalho empregou o método qualitativo dedutivo. Procurou-se também examinar a necessidade de que sejam buscadas fundamentações para os direitos humanos ainda nos dias de hoje. O pensamento kantiano, que justifica os direitos humanos no próprio homem se mostrou uma forma atual e adequada de fundamentação, pois nele os elementos que se destacam são a liberdade e a dignidade humana.
Faivel Getz, “Talmudic Youth” and “Dear Friend” of Vladimir Solovyov: Materials for a Biography (To the 170th anniversary of two friends, V.S. Solovyov and F.B. Getz)
Authors:   Institute of Philosophy of the Russian Academy of Sciences, Burmistrov K.Yu.
Published: April 2023

Faivel Bentsilovich Getz (Goetz, 1853–1931) is one of the people whose significance for the history of Russian philosophy and culture of the 19th – early 20th centuries is not in doubt, but their life and work, for various reasons, remain almost blank spots. For more than 20 years, Getz was in close contact with V.S. Solovyov, L.N. Tolstoy and a number of well-known Russian thinkers, writers, and politicians. In this article, we set ourselves several tasks. Firstly, we will briefly reconstruct the life path of this writer, journalist and public figure, both in Russia and after his departure from the country after the revolution. Secondly, we examine in detail his creative heritage, analyze his publications in various languages, and also offer a bibliography of books published by Getz in the 1880s – 1920s. Thirdly, the article contains a commented reprint of two publications about V.S. Solovyov, written by Getz in Riga in 1925 and dedicated to the philosopher's attitude towards Jews and the “Jewish question”. Finally, we publish an article in memory of Getz himself, written in 1932 by his friend E.K. Keuchel, who published many books about V.S. Solovyov both in Russian and in German. By introducing a significant amount of new information and texts into scientific circulation, we expect to arouse interest both in the figure and ideas of F.B. Getz, and to the study of a whole layer of publications about V.S. Solovyov in various languages that were published at the end of the 19th and beginning of the 20th centuries still eluding the attention of researchers.
V.S. Solovyov’s Sophia and Dante’s Beatrice
Authors:   Yniversity of Toronto, Helleman W.E.
Published: April 2023

In this study, the author claims that symbolist poets, such as A. Blok, who saw echoes of Dante's Beatrice in the image of Sofia by Vladimir Solovyov, were not mistaken. Parallels are drawn in the development of the theme of love in the works of symbolists and V. Solovyov. It is noted that the symbolist understanding of Sofia did not take into account the influence of Romanticism on the image of Sofia V. Solovyov, dominating in Russian culture and aesthetics of the late XIX century. Using historical, literary and philosophical methods, the author analyzes the reception of the image of Dante's Beatrice and Blokov's Beautiful Lady in the works of V. Solovyov. It is proved that the theme of love for a Beautiful Lady among the troubadours, transformed into a means of expressing love for God in the Divine Comedy, is also characteristic of Solovyov's theurgic approach to the transformative nature of beauty and love. Recognizing the historical distance between Dante and Solovyov, using literary and philosophical analysis, the use of themes of Christian Platonism is argued to solve two significant unresolved problems in understanding the image of Sophia: firstly, the gnostic dualism of the image of Sophia in Solovyov; secondly, the question of the divine status of Sophia. It is concluded that the reception of Platonism in Solovyov's work and his mystical understanding of the image of Sophia remained predominantly monistic, in accordance with traditional Neoplatonic mysticism.
The idea of a world empire of culture in the views of V.S. Solovyov and in the Russian socio-political consciousness of the XIX century
Authors:   Saint-Petersburg State University, Evlampiev I.I.
Published: April 2023

The paper considers the formation of the idea of a world empire in the Russian philosophical and socio-political thought of the 19th century, embracing all of humanity and based on the absolute priority of high culture. Based on the analysis of the encyclopedic article by V.S. Solovyov on this subject, it is shown that the source of this idea is in the philosophy of I.G. Fichte, who was one of the first to talk about a united Europe in his work “The Main Features of the Modern Era”, but recognized not the economy and politics, but high culture as the main factor of unity. A similar model of the coming world civilization is presented in the works about Russia and the West by F.I. Tyutchev. It is noted that the idea of “world revolution” in the book by A.I. Herzen “On the Development of Revolutionary Ideas in Russia” refers to the creation of a universal “kingdom of culture” headed by Russia in the sense that Fichte thought of it. Analysis of the work of A.I. Herzen shows that this socio-political figure was skeptical about the real revolutionary movement in Russia (which led to the revolution of 1917), calling it “autocracy in reverse”, and considered Peter I to be the true initiator of the true revolution. The paradoxical similarity of the views of Tyutchev and Herzen about the coming “kingdom of culture” was noted by F.M. Dostoevsky, who expressed his point of view in the famous Pushkin speech and through Versilov’s hero of the novel “The Row Youth”. It is concluded that the Russian Empire in its history sometimes approached the ideal model of the “kingdom of culture”, which famous Russian thinkers of the 19th century dreamed of.
V.S. Solovyov and A.N. Ostrovsky: Creative Convergence and Repulsion as a Reflection of The Era of Change
Authors:   Kostroma State University, Edoshina I.A.
Published: April 2023

The problem of the influence of the ideas of Vl.S. Solovyov on the theatrical art of the Silver Age was considered in the articles by Y.D. Kuzin, N.O. Osipova, E.S. Shevchenko, N.G. Yurina, O.A. Dashevskaya, O.K. Strashkova, I.B. Rodnyanskaya. The attention of all researchers was focused on the dramatic experiments of Vl.S. Solovyov, in which both elements of the theater of the medieval and the nineteenth century were found. In the synthesis of these elements, the researchers saw the prototype of the early twentieth century theater. In this article, the question of possible creative intersections of Vl.S. Solovyov and A.N. Ostrovsky is asked for the first time. The material for the study was the work of Vl.S. Solovyov of the 1880–1890 and “late” plays by A.N. Ostrovsky. Special attention is paid to the analysis of such texts by Vl.S. Solovyov, as “Readings on God-manhood”, “The General Meaning of Art”, “The Meaning of Love”, and from the plays of A.N. Ostrovsky, in addition to the “late” ones (from “Dowry” to “Not of this world”), the text of “Thunderstorms” is used. With a general ontological approach in understanding the essence of the problem, when carrying out analytical procedures, methods such as historical and cultural (to comprehend the specifics of the era), biographical (to reproduce significant facts from the life of Vl.S. Solovyov and A.N. Ostrovsky), cultural-philosophical (when analyzing texts). The article discusses the specific features of the era of the 1870s in Russia, a response to which became the plays of A.N. Ostrovsky and “Readings on God-Mankin” by Vl.S. Solovyov. The reasons for Vl.S. Solovyov to the elements of theatrical aesthetics are explained, these elements are compared with the theoretical and practical considerations of A.N. Ostrovsky. As a result, the author of the article argues that despite the similarity of views, which was facilitated by the era, there were fundamental differences. These differences are associated with a different approach to the use of elements of theatrical aesthetics: practical in the plays and texts of A.N. Ostrovsky and theoretical and philosophical in the texts of Vl.S. Solovyov. In the “late” plays of A.N. Ostrovsky, questions of a philosophical nature were raised, the answers to which could be found in the texts of Vl.S. Solovyov.
Kohanovskaya (N.S. Sokhanskaya) and her Fate in Russian Literature (to the 200th anniversary of the birth)
Authors:   Institute of Russian Literature (Pushkinskij Dom) Russian Academy of Sciences, Fetisenko O.L.
Published: April 2023

The article is devoted to the creative heritage of Kokhanovskaya (Nadezhda Stepanovna Sokhanskaya (1823–1884)), an outstanding writer, a brilliant publicist, collaborator of all editions of I.S. Aksakov, the first female folklorist in Russia, and timed to coincide with her 200th anniversary. The author gives facts about the possible correspondence of this writer with Vl. Solovyov, it is reported on a documented exchange of letters between them, gives her review of Solovyov’s article “On the True Case”. The researcher highlights the main milestones of Kokhanovskaya’s life path, notes her belonging to the so-called “positive direction” in Russian literature. The article attempts to determine the place of the writer in Russian culture and her inherent gifts – the creation of her own language and artistic world, the resurrection of antiquity and a lively response to modern events, the combination of active and contemplative Christianity and the ability to present moral lessons without didacticism and sentimentality. In conclusion, the author informs about the academic collection of works and letters of Kokhanovskaya published by the Pushkin House (Institute of Russian Literature) since 2023.
CHINESE AND JAPANESE VAGUE REFUSAL SPEECH ACT: SIMILARITIES AND DIFFERENCES
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Qingchuan Jiang
Published: April 2023

Any language is not only a part of the culture but also its carrier. Different national languages embody their unique traditional culture and at the same time are a reflection of the national way of thinking of their speakers, national customs, social values, etc. According to the division into "high-context" and "low-context" cultures, which was proposed by Hall E. T. (1959), China and Japan appear to be the representatives of high-context culture. In a high-context culture, the main transmission of information depends on the context. A large amount of information strongly depends on the context, while only a small part of the information is conveyed with the help of lingual forms. High-context cultures emphasize indirect ways of expression. That is, in Chinese and Japanese languages, only a small part of the information is transmitted verbally, while the main part of it is provided through the context and circumstances of communication. Meanwhile under the influence of the ideology of Confucianism, the avocation of "propriety" is reflected in the demand for people's polite behavior in both China and Japan. Therefore, when interacting with people, one has to pay more attention to preserving the face of others and minimizing the threat to others' faces, in particular with the help of euphemistic and subtle language expressions. Refusal is such a speech act that threatens the face of all communication participants. Therefore, in Chinese and Japanese lingual cultures, the vague speech act of refusal is usually exercised in order to avoid expressing the intention of "rejection" directly with the help of vague and unclear expressions, so as to leave a buffer zone for both parties. On the one hand, to reduce the threat of losing face by both counterparties; on the other hand, to maintain good interpersonal relations. However, each of the two languages has its own typological and cultural characteristics, and in this article, the author sets the main goal ̶ to find out the similarities and differences between the Chinese and Japanese vague refusal speech acts based on the grammatical and cultural peculiarities of the languages in focus.
TO CHOOSE THE SKY AS THE EXISTENCE OF A PATH
Authors:   Kamianets-Podilskyi Ivan Ohiienko National University, Rarytskyi Oleh
Published: April 2023

[Anna Honcharyk: I Choose This Sky. Compiler E. Solovei. Kyiv: Dukh i Litera, 2022. 280 p; il.]
Strategist-autocrator Tiberius in War with Avars 568–570
Authors:   Ivan Franko National University of Lviv, Lahodych Volodymyr
Published: April 2023

Among Justinian the Great’s (527–565) successors, the personality and career of Byzantine warlord and politician Tiberius stand out. Despite the lack of statements about Tiberius’ early life, there were enough facts about the circumstances that led to his rise in the hierarchy of late Roman society. Emperor Justin II (565–578) trusted him personally, and he also participated in diplomatic negotiations with barbarians, where he represented Roman interests. Along with the weak health of Justin, these circumstances contributed to the following adoption of a future warlord by the Emperor’s Family. Relationship with Avar Khanate had already been in priority for Tiberius before he was elected Justin’s co-ruler in 576. Taking part in talks with nomads, Tiberius focused on the necessity of renewing alliances with the Avars and directing military power toward the tribes that posed a constant threat to the Empire. In perspective, Tiberius’ course of appeasement with the nomads brought an end to the war in 568–570. His actions provided the Empire with the possibility of strengthening political and military might in the Danube limes in the next few years and also politically neutralized the Avars through permanent military conflicts with their closest neighbors. In practice, the Nomad noble, being enriched with money from Constantinople, made peace with Romeis. The Avars increased their military strength by focusing their efforts on conquering Slavs. This circumstance in one way let the nomads to start their foreign policy pressure on Empire again. Political vicissitudes of the last quarter of the VI cent. were accompanied by the exchange of ambassadorial missions, the provision of gifts, as a means of influencing third parties to a specific political course in the early Middle Ages.
Marriage Portraits of James I (VI) and Anne of Denmark: Representative Potential and its Realization
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Levchenko Illia
Published: April 2023

In the article, the author analyzed the representative potential of marital and family portraits of the English King James I and Anne of Denmark. The author also considered the role of these portraits in creating and promoting the image of royal power. The methodological basis of the study was the methods of art history, such as iconography and iconology classical methods. The use of political iconography approaches became especially important for research. A total of 10 images were discovered, examined, and analyzed, including engravings (8), the painting (1), and the medal (1). The small number of discovered sources indicates two points. First, some of the portraits were destroyed during the revolutionary events of the middle – second half of the 17th century, known as the «English Revolution». Second, marital portraits did not play a significant role in the representative practices of King James I, who was oriented towards the representative practices of his predecessor, Elizabeth I Tudor. At the same time, the institution of the royal family remained an important and exemplary role model for the entire society. Visual sources supported this model. In particular, in the revealed and analyzed portraits, the king appears as the head of the family (paterfamilias), an example to follow, a bearer of knightly virtues and ideals. If marital portraits are an example of the superimposition of two figures (King James I and Queen consort Anne of Denmark), almost not united in terms of plot and composition, then family portraits, on the contrary, need to be more structured. Family portraits unite, as a rule, the predecessors and sometimes the predecessors of the dynasty. Artists Willem van de Passe and Gerrit Mountain depict a family tree and deceased persons. The purpose of these portraits is to construct the dynasty’s history, emphasize its legitimacy, glorify its future, and promote the children in the social (court) hierarchy.
Pharmacogenetics of new oral anticoagulants
Authors: Azimova Bella A. , Nikolayev Konstsantin Yu. , Vorobyov Anton S. , Urvantseva Irina A.
Published: April 2023

The review presents modern studies the effect of genetic polymorphisms on the efficienty and safety of therapy with new oral anticoagulants. Hepatic carboxylesterase encoded by the CES1 gene and P-glycoprotein encoded by the ABCB1 gene affect dabigatran pharmacokinetics. The role of glucuronidation enzymes (UGT2B15, UGT1A9, UGT2B7) involved in active dabigatran metabolism is poorly understood. An increase in the peak apixaban concentration was noted in patients with the rs4148738 polymorphism of the ABCB1 gene. Polymorphisms rs776746 and rs77674 of the CYP3A5 gene affect concentration of apixaban in Asian patients and thus increased the bleeding risk. The effect SULT1A1 sulfotransferase on the metabolism of apixaban has yet to be studied. The BCRP protein encoded by the ABCG2 gene is a poorly studied but promising direction for the pharmacokinetics of apixaban. ABCB1 and CYP3A4 of the cytochrome P450 system affect the rivaroxaban metabolism, however, the number of studies devoted to examining the effect of polymorphisms of these genes on the rivaroxaban pharmacokinetics limited. Thus, large studies are needed to clarify the clinical relevance of genotyping in target patients taking new oral anticoagulants.
Anthracycline-induced cardiomyopathy in the long-term period after chemotherapy: clinical case
Authors: Kozjavin Nikita A. , Mureyko Ekaterina A. , Nikiforov Viktor S. , Beljaev Alexey M.
Published: April 2023

Background. As is known, the treatment of the oncological process leads either to the occurrence of cardiovascular pathology, or to an increase in the risk of death from cardiovascular diseases. Currently, the concept of ˝cardiovascular toxicity˝ has been introduced, which is associated with the treatment of cancer (CTR-CVT). Systemic drug anthracycline-containing anticancer therapy can cause a number of cardiovascular complications, such as myocardial systolic dysfunction, coronary heart disease, cardiac arrhythmias, arterial hypertension. Particular attention is paid to anthracycline drugs, because they are still included in combinations of many adjuvant therapy regimens and first-line treatment of both the most common cancers and rarer ones.
Clinical Case Description. The article presents a clinical case of a patient who received adjuvant polychemotherapy for breast cancer in 2017 with AC 4 D 4 regimen, in which chronic anthracycline-induced cardiomyopathy manifested years after completion of antitumor therapy. The development of anthracycline cardiomyopathy is possible even in patients with initially low cardiac risk.
Conclusion. The clinical case highlights the importance of monitoring patients after the end of anthracycline antitumor therapy, in particular, they are shown to periodically perform an echocardiographic study in order to detect delayed asymptomatic myocardial dysfunction.
A clinical case of multifocal chorioretinitis associated with Herpes zoster
Authors: Martirosyan Svetlana S. , Ginoyan Ofelya B. , Hovakimyan Anna V. , Simonyan Diana R. , Musheghyan Ilona K.
Published: April 2023

The Varicella-Zoster virus (VZV) is the etiologic agent of one of the most common infectious diseases among children, chickenpox. In its recurrent form it may cause a far more devastating disease, Herpes zoster. The disease can be manifested as conjunctivitis, episcleritis, scleritis, keratitis, anterior uveitis. Chorioretinal lesions may occur in patients with immunosuppression.
A 14-year-old male patient has been admitted to the Ophthalmologic center after S.V. Malayan with complaints of visual decrease, redness and pains. In the history of the patient the transferred chickenpox was marked a few months ago. By biomicroscopic and fundoscopic examination conjunctival hyperemia, corneal precipitates, severe inflammatory reaction in the anterior chamber, sectoral iris atrophy, posterior synechiae, yellow-white multifocal, peripheral lesions on the fundus of both eyes and pigmented macular scar in the right eye were found out. Laboratory tests showed high levels of anti-VZV IgG. Treatment was prescribed in the form of local instillations and subtenon injections, as well as antiviral tablets. As a result of treatment, remission of inflammatory process and improvement of visual acuity were registered. The specific characteristic of present case study is the description of single clinical manifestations of Herpes zoster, which are necessary to detect for correct and timely treatment.
A giant foreign body of the orbit. A clinical case
Authors: Filatova Irina A.
Published: April 2023

The article describes a casuistic case of a long asymptomatic stay of a giant foreign body in the orbit and of its removal. Immediately after the injury and at primary surgical treatment, the foreign body was not diagnosed. The patient did not have any complaints for a long time, then gradually there was a periodic double vision when looking straight ahead, a dense formation under the eyebrow began to be revealed by palpation. The foreign body was successfully removed almost a year after the injury.
Features of differential diagnosis of direct carotid-cavernous fistula. Clinical case
Authors: Tabashnikova Tatyana V. , Serova Natalya K. , Yakovlev Sergey B.
Published: April 2023

Traumatic brain injury can cause various pathological conditions both in the eyeball and in the cranial cavity. The presented clinical case demonstrates the features of differential diagnosis of direct carotid-cavernous fistula and secondary post-traumatic glaucoma. Direct carotid-cavernous fistula is the formation of a communication between the internal carotid artery and the cavernous sinus and the discharge of arterial blood into it. The first symptom of a carotid-cavernous fistula is a pulsating noise in the head and above the eye. The manifest signs in the clinical picture are the signs of obstruction of venous outflow from the eye and the orbit: proptosis, eyelid edema and chemosis, congestive redness of the eye, varicose subcutaneous veins of the eyelids, as well as dilated ophthalmic vein visualized by ultrasound of the orbit, ophthalmic hypertension, oculomotor disorders, state of the fundus. The clinical picture in patients with secondary post-traumatic contusion glaucoma, in addition to an increase in intraocular pressure, is characterized by the presence of a congestive redness of the eye, changes in the cornea from mild superficial opacities to more dense ones, luxation or subluxation of the lens into the anterior chamber or vitreous, destruction of the vitreous or intraocular hemorrhage. The similarity of clinical manifestations of traumatic carotid-cavernous fistula and secondary post-traumatic glaucoma can cause difficulties in differential diagnosis.
Modern strategy and standards of treatment of lower eyelid skin malignant neoplasms
Authors: Polyakov Andrey P. , Davydov Dmitry V. , Novikova Irina V. , Sugaipov Adam L. , Kuznetsova Olga S. , Naumova Elena A.
Published: April 2023

Cases of surgical treatment of basal cell skin carcinoma of the lower eyelid are rarely described in the world literature. Perhaps this is due to the search for new non-surgical treatment methods or to the fact that this localization is poorly represented in the total incidence of basal cell skin cancer. However, the operative method, recommended as the main line of treatment by both domestic and foreign clinical recommendations, is still recognized as the most radical and aesthetically acceptable method of treatment. Non-radical treatment of the tumor leads, in turn, to relapses of the disease, to the emergence of systemic metastatic foci due to the lymphogenic and hematogenic spread of tumor cells. In the article we describe the experience of surgical treatment of patients suffering from basal cell skin carcinoma of the lower eyelid of varying degrees of extension.
Clinical efficacy of early vitrectomy in patients with severe blunt ocular trauma
Authors: Subbotina Serafima N. , Shamkin Sergey S. , Stepanyants Armen B.
Published: April 2023

BACKGROUND: Eye injury is an actual problem, occupying a leading position among the main causes of blindness and low vision, accounting for 22.8% in the structure of primary visual disability, of which 53% of cases are due to closed eye injury. Despite the development and widespread introduction into practice of methods of high-tech care for patients of this profile, there are a number of complications that poorly respond to treatment, ultimately leading to the loss of visual function of the injured eye.
AIM: Evaluation of the effectiveness of early vitrectomy in patients with severe blunt ocular trauma, based on clinical results obtained during treatment and postoperative follow-up.
MATERIALS AND METHODS: The study included 34 patients (34 eyes) with contusion-type eye injury. The mean age of patients was 39 years, among them 30 were men (88.24%) and 4 (11.76%) women. Patients were divided into 2 groups. Group 1 included 11 patients (10 men, 1 woman) with an open-type eye injury with a subconjunctival scleral rupture; upon admission, visual acuity varied from incorrect light projection to 0.01. In group 2, there were 23 patients (20 men, 3 women) with severe closed eye injury, upon admission to the hospital, visual acuity ranged from incorrect light projection to 0.06. In all cases, patients underwent subtotal three-port vitrectomy at an early date (up to 3 days) after injury.
RESULTS: On the 1st day after surgery, there was an improvement in visual acuity in all patients. The follow-up period for patients was 6 months. All included patients had a stable anatomical result, no cases of subatrophy were noted, satisfactory functional results were achieved - visual acuity varied from 0.02 to 0.8. After 6 months, 32 out of 34 eyes (94.12%) showed no signs of proliferative vitreoretinopathy. In 2 patients (18.18%) from group 1, the development of proliferative vitreoretinopathy under silicone oil was revealed. Epiretinal membrane was diagnosed in 2 patients (8.7%) from group 2 and in 1 patient (9.09%) from group 1.
CONCLUSIONS: Obtained clinical results of treatment of patients with severe blunt ocular trauma indicate the expediency of vitrectomy in early stages after injury, which is an effective treatment method. Long-term results demonstrate stable functional results for 6 months. Vitrectomy performed early after injury serves for prevention of proliferative vitreoretinopathy, but does not completely exclude its development. Performing surgery early after injury increases the prospects for preserving visual functions of the eye and is a positive prognostic factor.
Surgical methods of retinal pigment epithelium transplantation in rabbits in experiment
Authors: Neroeva Natalia V. , Lagarkova Maria A. , Ilyukhin Pavel A. , Izmailova Natalya S. , Utkina Olga Alexandrovna , Laktionov Pavel P. , Chernonosova Vera S. , Kharitonov Anatoly E.
Published: April 2023

The article is devoted to the study of surgical methods of retinal pigment epithelium transplantation in experiment on rabbits. The history of retinal pigment epithelium transplantation is briefly characterized in the study. Characteristics of the methods used are presented, their limitations, possibilities, and requirements for implementation in practice are highlighted. The results of transplantation of suspension of retinal pigment epithelium cells differentiated from human induced pluripotent stem cells (IPSC-RPE) without and with the use of platelet-rich blood plasma (PRP) are also considered. According to the results of the analysis we have developed modified methods of IPSC-RPE cells transplantation in the experiment on rabbits, which allow to reduce the number of postoperative complications, which provides the best therapeutic effect. Prospects for further studies are associated with a comparative analysis of the proposed techniques in terms of cell survival at different terms, anatomical integration and functional efficiency in the dynamics.
The options of an individual approach to the modification of sinustrabeculectomy for hypotensive effect prolongation
Authors: Suleiman Elena A. , Petrov Sergey Yu.
Published: April 2023

BACKGROUND: Reducing scarring in the postoperative period is one of the main tasks of glaucoma surgery.

AIM: To develop new modifications of sinustrabeculectomy in the surgical treatment of primary open-angle glaucoma normalizing and prolonging the outflow of aqueous humor along newly formed pathways.

MATERIALS AND METHODS: Surgical procedures were performed in 106 patients (109 eyes) with primary open-angle glaucoma of moderate and advanced stages, without any history of previous surgeries. Patients were divided into groups: 1a 25 patients (25 eyes) who underwent sinustrabeculectomy with the formation of grooves for the intramuscular fluid outflow, 1b 26 patients (28 eyes) who underwent of sinustrabeculectomy with scleral flap twisting, 1c 28 patients(29 eyes) who underwent sinustrabeculectomy with scleral flap stitching, and the control group 27 patients (27 eyes) who underwent routine sinustrabeculectomy. The follow-up duration was up to 24 months.

RESULTS: In 1 month after surgery, the average level of intramuscular pressure was comparable and remained low in all groups. Complete compensation of intramuscular pressure in groups 1a, 1b and 1c was observed in 80%, 75% and 76% of cases; partial in 16%, 18% and 21% of cases; failure in 4%, 7% and 3% of cases, respectively. In the control group (2), complete hypotensive success was noted in 55% of cases; partial in 30% of cases; failure in 15% of cases.

CONCLUSIONS: Developed new methods of sinustrabeculectomy allow to obtain a prolonged hypotensive effect.
Comparison and comparability of pneumotonometry and rebound tonometry results with Maklakov’s applanation tonometry
Authors: Belov Dmitrii F. , Zumbulidze Natalia G. , Yusupova Amina I. , Kasymov Farhod O.
Published: April 2023

BACKGROUND: Introduction and use of various tonometry methods can lead to misinterpretation of intraocular pressure results and influence the choice of treating approaches by ophthalmologist in a glaucoma patient.
AIM: To compare pneumotonometry and rebound tonometry results with Maklakovs applanation tonometry and to develop corrections for their comparability.
MATERIALS AND METHODS: The study included 75 patients. All subjects underwent Maklakov applanation tonometry (10 g) and pachymetry (Topcon SP-3000P). In 48 patients (94 eyes) of the 1st group, pneumotonometry (TONOREF II Nidek) was performed, and 27 patients of the 2nd group (52 eyes) underwent rebound tonometry (iCare IC-100).
RESULTS: The mean difference in intraocular pressure level in the 1st group was 4.81 (p 0.001), and in the 2nd 0.98 mmHg (p = 0.399). Both methods pneumo- and rebound tonometry showed underestimated results with intraocular pressure less than 23.0 and 22.5 mmHg (respectively) relative to applanation tonometry and, conversely, overestimated intraocular pressure when these values were exceeded. A significant (p 0.001) strong (R2 = 0.86) relationship between applanation and rebound tonometry was obtained, which made it possible, using regression analysis, to develop a formula for recalculating results of iCare tonometry into those of Maklakov tonometry: PMaklakov = 0.40 PiCare + 13.44.
CONCLUSIONS: Both pneumo- and rebound tonometry demonstrate adequate results of P0 with intraocular pressure below 23.0 and 22.5 mmHg (respectively) and overestimate the results when these values are exceeded. The developed formula allows converting the results of iCare tonometry into the values of the Maklakovs tonometry.
Keefektifan Bimbingan Kelompok dengan Teknik Structured Learning Approach untuk Meningkatkan Perilaku Asertif Siswa SMK dalam Mencegah Pelecehan Seksual
Authors: Al Atikho Khoirunnisa , Ramli M. , Wahyuni Fitri
Published: April 2023

Abstract: Adolescents ability to be assertive is a life skill that is crucial to their growth at this point and is essential in all facets of daily life. This study uses group guidance  and the SLA technique to enhance students' assertive behavior in order to prevent sexual harassment. The one group pretest and posttest design is used in this quantitative research approach, which also uses a quasi-experimental research type. The participants in this study are 10th grade students at SMK Negeri 4 Malang who are majoring in graphic engineering. Ten students were chosen as research participants using the purposive sampling method. The instrument used is the assertive behavior scale by Galassi (1997). Ten kids from the overall population got scores for moderate and low assertive behavior, according to the results of the pretest. The group guidance session with 10 students took place over the course of 4 meetings. The results of the analysis of pre-test and post-test scores through the Wilcoxon test showed that group counseling using the SLA technique was effective in increasing assertive behavior in preventing sexual harassment based on the results of Asymp Sig. of 0.005 which means H1 is accepted and H0 is rejected.

Abstrak: Kemampuan remaja untuk bersikap asertif merupakan keterampilan hidup yang penting untuk pertumbuhan mereka pada saat ini dan penting terhadap aspek kehidupan sehari-hari. Penelitian ini menggunakan bimbingan kelompok dan teknik SLA untuk meningkatkan perilaku asertif siswa guna mencegah terjadinya pelecehan seksual. One group pretest and posttest design digunakan dalam pendekatan penelitian kuantitatif ini, yang juga menggunakan jenis penelitian kuasi eksperimen. Partisipan dalam penelitian ini adalah siswa kelas X SMK Negeri 4 Malang yang mengambil jurusan teknik grafika. Sepuluh siswa dipilih sebagai partisipan penelitian dengan menggunakan metode purposive sampling. Instrumen yang digunakan adalah skala perilaku asertif oleh Galassi (1997).  Berdasarkan hasil pretest diperoleh hasil bahwa terdapat 10 siswa yang diambil secara acak dari seluruh populasi untuk diberikan treatment. Bimbingan kelompok dilakukan sebanyak 4 kali pertemuan. Hasil analisis skor pre-test dan post-test melalui uji wilcoxon yang menunjukkan hasil bahwa bimbingan kelompok dengan teknik SLA efektif digunakan untuk meningkatkan perilaku asertif dalam mencegah pelecehan seksual yang didasarkan pada hasil Asymp Sig. sebesar 0.005 yang berarti H1 diterima dan H0 ditolak.
Spiritual Leadership: Konsep Baru dalam Kemampuan Manajemen Kepala Sekolah
Authors: Rachmawati Indriyana , Laksana Eko Pramudya , Rahmawati Novi Rosita
Published: April 2023

Abstract: Spiritual leadership is an important new concept that should be owned by school principals for good school management. This study systematically describes the development of spiritual leadership as a principal's leadership management based on empirical evidence. The research method used is the literature review, the criteria for the selected articles, including educational settings, and the year of publication 2016-2021. The number of articles reviewed was nine scientific journal articles covering the topic of spiritual leadership. The results of the study show that the form of leadership management carried out by the principal in implementing the spiritual leadership model is developing expectations of all school staff, having a vision for the future, being able to understand and foster differences, having good communication with all school staff, being motivated, willing to accept feedback in leadership, able to manage conflict, efficient in work and exemplary professional commitment.

Abstrak: Kepemimpinan spiritual adalah konsep baru yang penting dan perlu dimiliki kepala sekolah untuk melakukan manajemen sekolah yang baik. Tujuan penelitian ini adalah untuk menggambarkan secara sistematis tentang pengembangan spiritual leadership sebagai manajemen kepemimpinan kepala sekolah berdasarkan bukti empiris. Metode penelitian yang digunakan yaitu kajian pustaka, kriteria artikel yang dipilih, diantaranya pada setting pendidikan dan tahun terbit 2016-2021. Jumlah artikel yang dikaji sebanyak 9 artikel jurnal ilmiah yang memuat topik kepemimpinan spiritual. Hasil penelitian menunjukkan bahwa bentuk manajemen kepemimpinan yang dilakukan kepala sekolah dalam menerapkan model kepemimpinan spiritual yaitu mengembangkan harapan seluruh staf sekolah, memiliki visi di masa depan, mampu memahami dan membina perbedaan, memiliki komunikasi yang baik dengan seluruh staf sekolah, memotivasi, bersedia menerima umpan balik dalam kepemimpinan, mampu mengelola konflik, efisien dalam bekerja dan komitmen profesional yang baik.
Artificial Intelligence and Traditional Machine Learning to Deep Neural Networks: A Study for Social Implications
Authors: Pasupuleti Mahesh Babu
Published: April 2023

There are intriguing opportunities on the road to broad usage of artificial intelligence, as well as challenges that must be solved in order to use machine learning and artificial intelligence technology in industries. On the basis of Google Scholar data, this work systematizes artificial intelligence sections and analyzes the dynamics of changes in the number of scientific papers in machine learning sections. The process of data collection and calculation of dynamic indicators of changes in publication activity, such as the growth rate and acceleration of growth of scientific publications, is presented in detail. Particularly evident in the analysis of publishing activity was the high level of interest in current transformer models, the production of datasets for specific industries, and a significant growth in interest in explainable machine learning approaches. As indicated by the negative correlation between the number of publications published and the number of articles published in a given year, relatively minor study topics are gaining an increasing amount of attention. Results demonstrate that, despite the method's limitations, it is possible to (1) identify rapidly expanding fields of research, irrespective of the number of papers published, and (2) anticipate publication activity in the short term with sufficient accuracy for practical purposes. Results for more than 400 search queries relating to designated study topics and the application of machine learning models to industries are presented in this article in a single document. The suggested method assesses the growth and fall of scientific areas that are related with specific key phrases in terms of their dynamics of growth and decline. It does not necessitate access to huge bibliometric archives and enables for the generation of quantitative estimates of dynamic indicators in a reasonably short time frame.
KONAKLAMA İŞLETMELERİNDE DEPARTMAN BAZINDA MALİYETLERİN HESAPLANMASI VE MUHASEBELEŞTİRİLMESİNE YÖNELİK BİR YÖNTEM ÖNERİSİ
Authors: MERİÇ Engin
Published: April 2023

Tüm sektörlerde olduğu gibi konaklama işletmeleri de kârlılık hedefli işletmeler olup, kârlılıklarını koruyabilmeleri ve sürdürülebilir kılmaları maliyetlerini doğru biçimde hesaplayabilmelerinden geçmektedir. Üretim (mamul/hizmet) işletmelerinde departman bazında muhasebe kayıtlarının yapılmasındaki amaç kayıt düzeni üzerinden kontrole yöneliktir. Bu kapsamda elde edilecek veriler oluşturulacak ek hesaplara bağlıdır. Bu şekilde bir kayıt düzeni sayesinde işletmelerde gelir, gider ve maliyetlerin departmanlar bazında takip edilip gerekli durumlarda müdahale edilmesi ve istenen sıklıkta kontrol edilebilmesi büyük önem taşımaktadır. Bu bağlamda çalışmanın amacı, hizmet üretim maliyetlerinin departman bazında muhasebeleştirilmesine yönelik bir yöntem önerisinde bulunarak konaklama işletmelerinin bu konudaki muhasebesel uygulamalarına ve iç kontrole katkı sağlamaktır. Bu amaçla hipotetik veriler kullanılarak bir yöntem önerisinde bulunulmuştur. Önerilen maliyet kontrol yöntemi 9 adımda gerçekleştirilerek çalışmaya dahil edilmiştir. Çalışmada önerilen yöntem ile oluşturulan yiyecek-içecek maliyet tabloları sayesinde elde edilen veriler mizan ile balans sağlamıştır. Önerilen bu yöntem ile herhangi bir manuel bilgi, belge ve veriye gereksinim duyulmadan mizan verileri üzerinden yiyecek-içecek maliyet tabloları hazırlanabileceği görülmüştür. Uygulanan yöntemde iç kontrole katkı sağlanması da hedeflendiğinden, gelir ve gider hesapları da analize elverişli detayda kullanılmış olup departman bazında yiyecek-içecek maliyet tabloları muhasebe kayıtlarından alınarak sonuçların herhangi bir olumsuzluk durumu ortadan kaldırılmıştır