bluuebunny/crossref_metadata_2025 huggingface dataset:
Plataformas digitales de reservas hoteleras, acciones acumulativas y su impacto en la estrategia de litigación internacional. Comentario a la Sentencia del TJUE de 24 de noviembre de 2020, c-59/19, wikingerhof vs. Booking
Authors: Antón Juárez Isabel
Published: March 2021

El objetivo de este trabajo es analizar la STJUE de 24 de noviembre de 2020. Este caso refleja muy bien los límites que existen entre lo que se puede considerar una materia contractual y extracontractual en atención al Reglamento UE 1215/2012 y el impacto que puede presentar tal calificación en la litigación transfronteriza. El objeto del presente artículo no persigue estudiar de forma exhaustiva los arts. 7.1 y art. 7.2. El objetivo es más bien que en base a esta resolución del TJUE poder esbozar unas líneas sobre los aspectos relevantes que se deben tener en cuenta en la organización de una estrategia de litigación internacional en los asuntos en los que se reclama responsabilidad civil extracontractual entre partes contratantes que tienen que ver con la aplicación privada de las normas de competencia.
La responsabilidad civil extracontractual derivada de accidentes de circulación. Sap Barcelona 19 junio 2020
Authors: Caamiña Domínguez Celia M.
Published: March 2021

El presente trabajo trata sobre la responsabilidad civil extracontractual derivada de un accidente de circulación ocurrido Portugal. Será analizada la competencia judicial internacional de los tribunales españoles conforme al Reglamento 1215/2012 y la aplicabilidad del Convenio de La Haya de 1971.
Observación jurisprudencial relativa a la ley aplicable a la compraventa de bienes inmuebles radicados en el extranjero. Estudio de caso a partir de la SAP de Murcia, núm. 98/2020
Authors: Carrizo Aguado David
Published: March 2021

A la luz de este pronunciamiento, el juez español viene a aclarar que, al amparo de la Ley preconstitucional 57/1968, de 27 de julio, no quedarán protegidos aquellos compradores que adquieran una vivienda con un fin no residencial. En concreto, considera que deben de excluirse los adquirentes que aun siendo personas físicas, compren la vivienda con un propósito inversionista, considerando como tales a los profesionales del campo inmobiliario. De igual modo, los particulares que sin ser profesionales del sector, invierten en la compra de viviendas en construcción para revenderlas durante el proceso de edificación o a su finalización. En concordancia con esta idea, resulta significativo valorar la eficacia del pacto de Ley inserto en un contrato de compraventa de un bien inmueble situado en el extranjero y, reflexionar en torno a la catalogación de consumidor en un marco difuso, asentado por la práctica habitual de inversión en el tráfico jurídico externo.
La modificación de medidas dictadas en sentencia extranjera: una cuestión pendiente (AP Cantabria 11 febrero 2020)
Authors: Dutrey Guantes Yolanda
Published: March 2021

La modificación de sentencias dictadas en países extranjeros sigue siendo una cuestión que no está definitivamente resuelta por nuestros tribunales. Hay dos cuestiones problemáticas. La primera de ellas es la duda acerca de la necesidad de solicitud de exequatur previo a la modificación de las medidas recogidas en una sentencia extranjera. La segunda es la falta de aplicación de las normas de competencia judicial internacional y su sustitución por normas de competencia judicial interna. Este auto muestra otra confusión que es otorgar la competencia para modificar las medidas de una sentencia extranjera al juez que dictó el exequatur.
Commentary on the judgment of the Provincial Court of Barcelona of 29 May 2020 [carriage of goods by sea from Ecuador to Spain under a bill of lading] [ES:APB:2020:3847a]
Authors: Echebarria Fernández Jonatan
Published: March 2021

El comentario a la sentencia de 29 de mayo de 2020 de la Audiencia Provincial de Barcelona (Sección 15) sobre el recurso de apelación interpuesto contra la Auto de 4 de junio de 2019 del Juzgado de lo Mercantil número 4 de Barcelona ofrece un análisis de la doctrina contradictoria que han seguido algunos tribunales españoles en relación con la transmisión del conocimiento de embarque (B/L), especialmente en lo que respecta a las cláusulas de jurisdicción a favor de otros tribunales de la Unión Europea (UE) incluidas en dicho documento, al tercero endosatario que no firmó dicho documento, desde la aprobación de la Ley de Navegación Marítima (LNM)14/2014 de 24 de julio de 2014. Los requisitos establecidos por el legislador europeo y las doctrinas del Tribunal de Justicia de la Unión Europea (TJUE) y de ciertas decisiones de los tribunales españoles divergen con respecto a los fundamentos de derecho de esta sentencia. Si bien la ley aplicable a la validez formal y sustantiva de dichos acuerdos se establece en el artículo 25 del Reglamento Bruselas I bis, el consentimiento de las partes contratantes se rige por la legislación nacional. El Tribunal Supremo español aún no ha dictado sentencia que especifique la eficacia del acuerdo de jurisdicción sobre un endosatario del conocimiento de embarque en caso de reclamaciones por daños a la mercancía desde la aprobación de la LNM. Por lo tanto, persisten discrepancias en esta polémica área.
La jurisprudencia del Tribunal Supremo español es clara: solicitar la renovación del pasaporte español ante el consulado es indicativo de la voluntad de conservación de la nacionalidad española (notas a la sentencia del Tribunal Supremo de 1 de junio de 2020)
Authors: Heredia Sánchez Lerdys S.
Published: March 2021

El presente comentario se refiere a la Sentencia del Tribunal Supremo español de fecha 1 de junio de 2020, por la que se resuelve un recurso de casación que trae como base la aplicación del artículo 24.3 del Código Civil, en cuanto a la causa de pérdida de la nacionalidad española de los nacidos en el extranjero de progenitor español también nacido fuera de España, por falta de declaración de conservación. Esta sentencia va en la misma línea que su antecesora, la dictada por el alto tribunal, el 19 de diciembre de 2019, y que ha venido a allanar el camino para evitar la pérdida de la nacionalidad a los españoles nacidos en el extranjero, al entender que con la mera solicitud de la renovación del pasaporte, se cumple con lo dispuesto en nuestro Código Civil.
Ley aplicable al contrato de trabajo internacional: la proscripción del «espigueo normativo» (STSJ de Madrid 10 de marzo 2020)
Authors: Juárez Pérez Pilar
Published: March 2021

La decisión judicial objeto de este análisis constituye un notable ejemplo de rigor y precisión en la aplicación del sistema de derecho internacional privado en el ámbito laboral. A raíz de una reivindicación salarial de unos trabajadores al servicio del Ministerio de Asuntos Exteriores en Argentina, el Tribunal aborda tanto la cuestión de la ley aplicable al contrato de trabajo como la de la prueba -o falta de ella- del derecho extranjero. En ambas materias evidencia un sólido conocimiento de las normas de derecho internacional privado y su doctrina interpretativa, de las que realiza una didáctica exposición y correctísima aplicación. Un análisis que le lleva a condenar el fraccionamiento legislativo del contrato cuando éste no es justificado, calificándolo de «espigueo de normas».
Doctrina del TJUE sobre la inmunidad de ejecución de las organizaciones internacionales y el ámbito de aplicación del Reglamento Bruselas I bis
Authors: Pérez Martín Lucas Andrés
Published: March 2021

En el año 2020 el TJUE ha enmarcado en dos importantes resoluciones los tipos de acciones en los que los negocios jurídicos de los estados o las organizaciones internacionales con personas del derecho privado se comprenden dentro del ámbito de aplicación del Reglamento Bruselas I bis como materia civil y mercantil y no están amparados por el principio de Derecho internacional de inmunidad de jurisdicción y ejecución. En el presente trabajo analizamos la Sentencia 3 septiembre 2020, que resuelve un procedimiento en el que la OTAN alegaba que el contrato de depósito de aseguramiento de los pagos de un contrato de suministro de combustible para asistir a la operación desarrollada en Afganistán tras los atentados de 2001 estaba amparado por el principio de inmunidad de ejecución, lo que negó el TJUE.
Competencia para la modificación de sentencias extranjeras de medidas ya reconocidas en España y trascencencia de la valoración judicial de traducciones contradictorias, a propósito de la sentencia de la AP Barcelona 10 enero 2020
Authors: Pérez Martín Lucas Andrés
Published: March 2021

En el presente trabajo analizamos diversos aspectos procesales de gran interés resueltos por la sentencia de la Audiencia Provincial de Barcelona 10 enero 2020. En primer lugar, la competencia para la modificación de una resolución judicial extranjera de medidas respecto a un menor, ya reconocida en España, en la que sigue ostentando competencia judicial internacional el lugar de residencia habitual del menor en aplicación de Convenio de La Haya de 1996 sobre responsabilidad parental y el Reglamento 4/2009. En segundo lugar, las exigencias de la consideración de la rebeldía establecidas en el Convenio bilateral entre Marruecos y España de 1997. Y, por último, y especialmente interesante por sus efectos, la valoración judicial de las traducciones contradictorias de las sentencias extranjeras.
Retroactividad de las capitulaciones matrimoniales al momento de celebración del matrimonio. Comentario de la SAP de Murcia, de 23 abril 2020
Authors: Rodríguez Rodrigo Juliana
Published: March 2021

La sentencia de la Audiencia Provincial de Murcia, objeto de comentario, resuelve un litigio que enfrenta a una pareja en relación con el régimen económico matrimonial respecto de un bien inmueble adquirido por el esposo. Según este, el bien debería inscribirse bajo el régimen de separación de bienes y considerarse bien privativo suyo. Según la mujer, el inmueble fue adquirido por el esposo mientras el régimen económico del matrimonio era el de gananciales y, por ello, el bien debería aparecer inscrito como común de ambos cónyuges.El elemento de discusión en el caso es el otorgamiento de unas capitulaciones matrimoniales, cua-tro después de la celebración de la unión conyugal, según las cuales el matrimonio se contrajo bajo el régimen de sociedad de gananciales. Esto es lo que alega la esposa para sostener que el bien inmueble debe ser ganancial. El marido, en cambio, argumenta que la ley aplicable al régimen económico de la pareja es el Derecho argelino y, por tanto, la separación de bienes.La Audiencia Provincial de Murcia, sin justificar la resolución del caso, establece que, como en las capitulaciones matrimoniales se dice que el matrimonio se celebró bajo el régimen de sociedad de ga-nanciales y el inmueble se adquirió antes del otorgamiento de las mismas, dicho bien debe considerarse ganancial porque no es hasta la fecha de celebración de las capitulaciones cuando el régimen económico de la pareja pasa a ser el de separación de bienes. Con esta solución del supuesto, estudiamos en este trabajo, fundamentalmente, los posibles efectos retroactivos de las capitulaciones matrimoniales.
Algunas cuestiones que plantea la modificación, en España, de las medidas de guarda y custodia adoptadas por tribunales extranjeros a la luz del Auto de la Audiencia Provincial de Barcelona de 29 de enero de 2020
Authors: Sabido Rodríguez Mercedes
Published: March 2021

El planteamiento de una demanda de modificación de las medidas de guarda y custodia adoptadas por un tribunal extranjero suscita algunas dificultades. En este trabajo analizaremos las que ha puesto de relieve el Auto de la Audiencia Provincial de Barcelona de 29 de enero de 2020 por el que se resuelve el recurso de apelación contra la resolución de instancia que inadmitió a trámite la demanda de modificación de medidas adoptadas por un tribunal marroquí. Abordaremos la determinación de la competencia judicial internacional de los tribunales españoles, diferenciándola de la competencia terri-torial; así como la problemática relativa a la exigencia o no del previo reconocimiento de la decisión cuya modificación se pretende y, en su caso, el procedimiento a seguir.
Nacimiento en el Sahara Occidental durante la etapa colonial y cuestiones de nacionalidad (STS 207/2020 de 29 de mayo. Sala de lo Civil. Pleno)
Authors: Vargas Gómez-Urrutia Marina
Published: March 2021

Nacer en España o nacer en territorio español a los efectos de aplicación del artículo 17.1 c) del Código civil tiene trascendencia jurídica si el interesado nació en la ex colonia del Sahara antes del 26 de febrero de 1976, fecha en que España abandonara aquel territorio. La sentencia 207/2020, de 29 de mayo del Pleno de la Sala de lo Civil del Tribunal Supremo aborda, no sin ciertas dudas y con un Voto particular, la cuestión acerca de qué nacionalidad tenían los naturales del Sahara antes y después de la Ley 40/1975. Tomando la doctrina de la Sala 3ª TS en relación con la consideración de apátridas de algunos saharauis y confirmando la postura de la DGRN sobre las consecuencias del no ejercicio del derecho de opción conforme al RD 2258/76, el Pleno de la Sala de lo Civil ha perdido una excelente oportunidad de declarar la inconstitucionalidad sobrevenida del citado RD de 1976. ¿Qué razones justifican el fallo? ¿Qué otros argumentos hubieran podido esgrimirse? Con este enfoque se aborda nuestro comentario.
The Importance of Making-While-Reading for Undergraduate Readers: An Example of Inductive SoTL
Authors: Hovland Ingie
Published: March 2021

This paper gives an example of an inductive Scholarship of Teaching and Learning (SoTL) process, adapting Anthony Ciccone’s five conditions of a meaningful SoTL question. Presenting a study on pre-class reading in an undergraduate religion class, I describe how my question went through five life stages. I began with nine different pre-class reading assignments. Students judged the “map” assignment to be most helpful. This led to a further question: why maps? In a close reading of students’ reading reflections, two themes stood out: students experienced maps as helping them create a mental overview of the reading, and maps facilitated greater ownership of the act of reading. In conclusion, I argue that humanities instructors who wish to teach advanced reading skills can start by providing pre-class assignments that allow for making-while-reading, and that this making should not be merged with other reading steps. In an epilogue I reflect on the inductive research process. I suggest that SoTL scholars who use this process may reach an impasse when deciding how to present meaningful answers because their conceptual answers will stand in tension with SoTL’s practical orientation. I propose focusing on conceptual generalization (rather than empirical generalization), while still foregrounding a balance between “what works” and “what is.”
Pertanggungjawaban Pidana Pelaku BDSM (Bondage, Discipline, Sadism and Masochism) yang Mengakibatkan Luka, Cacat atau Kematian
Authors: Putri Elok Fauzia Dwi
Published: March 2021

Dini ini, BDSM banyak dibicarakan dalam media sosial maupun dalam kehidupan sehari-hari. Banyak masyarakat yang tertarik dan penasaran untuk sekadar mengetahui atau terjun dalam dunia BDSM. Rasa penasaran dan kurangnya pengetahuan dapat menyebabkan kerugian seperti luka, cacat atau kematian kepada partner BDSM scene. BDSM bukan merupakan tindak pidana walaupun sangat erat kaitannya dengan kekerasan karena dilakukan dengan consent. Dalam ilmu kejiwaan, sadisme dan masokisme termasuk dalam parafilia. Namun, penyimpangan tersebut tidak dapat dijadikan sebagai alasan untuk menggugurkan pemidanaan dikarenakan bukan termasuk yang dikecualikan pada Pasal 44 KUHP. Sehingga, pelaku BDSM yang menyebabkan luka, cacat dan hilangnya nyawa akan tetap dipidana.
Lex Minus Quam Perfecta Pembatalan Merger Oleh KPPU Pasal 47 Undang-Undang Nomor 5 Tahun 1999
Authors: Chusna Fida Aifiya
Published: March 2021

KPPU memiliki tugas dan wewenang pengawasan bidang persaingan usaha, salah satunya kontrol merger. Merger dalam persaingan usaha meliputi penggabungan dan peleburan perusahaan. Pasal 47 UU No. 5 Tahun 1999 memberi kewenangan KPPU untuk menjatuhkan sanksi administratif berupa denda dan/atau penetapan pembatalan bagi merger yang dapat menimbulkan monopoli dan praktik persaingan usaha tidak sehat. Penelitian ini menggunakan metode normatif. Hasil penelitian menunjukkan bahwa benar KPPU memiliki wewenang membatalkan merger berdasarkan Pasal 47, tetapi tidak dapat dilaksanakan karena tidak ada peraturan yang mengatur pelaksanaannya. Jika KPPU menerbitkan penetapan pembatalan merger, maka akan diajukan keberatan oleh pelaku usaha. Pengadilan menerima keberatan karena tidak dapat dilaksanakan dan menimbulkan ketidakpastian hukum. Sehingga Pasal 47 dalam konteks pembatalan merger oleh KPPU adalah lex quam minus perfecta karena KPPU dapat menjatuhkan hukuman denda, tetapi tidak dapat membatalkan transaksi merger.
Factors Associated With Pediatric Pulmonary Tuberculosis Incidence In Surakarta City Health Office Work Area
Authors: Asyfiradayati, S.KM., M.PH. Rezania
Published: March 2021

Tuberkulosis merupakan penyakit yang menjadi perhatian global. Secara global sekitar 10,0 juta orang terkena penyakit TB pada tahun 2017 sebesar 5,8 juta orang dewasa, 3,2 juta perempuan dan 1,0 juta anak. Pada tahun 2018 diketahui bahwa berdasarkan survei prevalensi TB Paru Anak di Wilayah DKK Surakarta terjadi peningkatan. Penelitian ini dilakukan pada seluruh penderita TB paru anak yang datanya terekap di Dinas Kesehatan Surakarta pada triwulan tiga dan masih mengalami pengobatan dengan jumlah 46 kasus dan dilakukan dengan metode case control dengan perbandingan 1:1 sehingga melibatkan 92 sampel. Beberapa faktor yang perlu diteliti adalah riwayat kontak serumah, paparan asap rokok anggota serumah dan pemberian ASI eksklusif. Hasil penelitian diketahui bahwa ada hubungan antara faktor riwayat kontak serumah, faktor paparan asap rokok dan ASI eksklusif dengan masing-masing p value (0,00), (0,09) dan (0,03) dengan kejadian TB paru anak di wilayah kerja DKK Surakarta.Kata Kunci: Anak, faktor risiko, tuberkulosis.
PEMBELAJARAN MENGIDENTIFIKASI UNSUR-UNSUR INTRINSIK DALAM CERITA PENDEK PADA PESERTA DIDIK KELAS XI SMK NEGERI 2 BANJARMASIN
Authors: Nurena Mutia Puteri  , Maria Lusia Anita Sumaryati  , Faradina
Published: March 2021

Penelitian ini mendeskripsikan hasil penelitian mengenai perencanaan, pelaksanaan, penilaian, dan kendala dalam pembelajaran mengidentifikasi unsur intrinsik cerita pendek kelas XI PS B SMK Negeri 2 Banjarmasin. Metode penelitian, yaitu deskriptif dengan pendekatan kualitatif. Teknik pengumpulan data dengan observasi, wawancara, rekaman, dan dokumentasi. Datanya, yaitu persiapan guru dalam penyusunan RPP, materi yang ingin disampaikan, metode yang digunakan, dan proses penilaian belajar peserta didik. Hasil penelitian ini memperlihatkan pelaksanaan pembelajaran guru tidak sepenuhnya berpedoman pada RPP. Aktivitas yang ditunjukkan selama pembelajaran berlangsung berdasarkan observasi, yaitu guru lebih banyak berceramah saat menyampaikan materi dan aktivitas peserta didik terlihat tenang dan memerhatikan guru dalam menyampaikan materi meski beberapa peserta didik tidak memerhatikan dan mengobrol dengan temannya. Guru melaksanakan penilaian berdasarkan tiga ranah, yaitu penilaian sikap, pengetahuan, dan keterampilan. Beberapa kendala dalam pembelajaran dialami guru dan peserta didik.
FTIR STUDIES OF THE TEOS/TEVS XEROGEL STRUCTURE USING RAPID THERMAL PROCESSING METHOD
Authors: Mawaddah Yanti , Wati Linda Suci , Rampun Erdina Lulu Atika , Sumardi Anna , Lestari Aptar Eka , Assyaifi Zaini Lambri , Elma Muthia
Published: March 2021

The tetraethyl orthocycate (TEOS) is mainly used as a silica precursor. Silanol content of silica material is the main cause of low hydrostability which led to resulting in poor performance, especially in water treatment. The stronger bond strength formed by incorporating a carbon structure from triethoxy vinyl silane (TEVS). The xerogel fabrication resulted in the composition of TEOS: TEVS: EtOH: HNO3: H2O: NH3 to be 0.9: 0.1: 38: 0.00078: 5: 0.0003.   . The purpose is to study the structure of organosilica xerogel calcined at 350oC, 450oC and 600oC in the Fourier-transform infrared (FTIR) using rapid thermal processing. The deconvolution of FTIR spectra calculated using the Fityk software. The result of the best xerogel peak shows at calcination of 450°C with peak area siloxane of 15.39, silanol of 3.32 and silica carbon of 3.85.
Soluble Epoxide Hydrolase Inhibition Ameliorates Phenotype and Cognitive Capabilities in a Murine Model of Niemann Pick Disease Type C
Authors: Griñán-Ferré Christian , Companys-Alemany Julia , Jarné-Ferrer Julia , Codony Sandra , González-Castillo Célia , Ortuño-Sahagún Daniel , Vilageliu Lluïsa , Grinberg Daniel , Vázquez Santiago , Pallàs Mercè
Published: March 2021

Niemann-Pick type C (NPC) disease is a childhood autosomal recessive inherited rare neuro-degenerative disease, characterized by the accumulation of cholesterol and glycosphingolipids, implicating the autophagy-lysosome system. Inhibition of soluble epoxide hydrolase (sEH), an enzyme that metabolizes epoxy fatty acids (EpFAs) to 1,2-diols, exerts beneficial effects in mod-ulating inflammation and autophagy, critical features of the NPC disease. This study aimed to evaluate the effects of UB-EV-52 a sEH inhibitor (sEHi) in the Npc mouse model by administering for 4 weeks (5 mg/kg/day). Behavioral and cognitive assays (open field test (OF), elevated plus maze (EPM), novel object recognition test (NORT) and object location test (OLT) demonstrated that treatment produced an improvement in short- and long-term memory as well as in spatial memory. Moreover, the treatment with UB-EV-52 increased body weight and the lifespan by 25% and re-duced gene expression of the inflammatory markers (i.e. Il-1β and Mcp1) and improved oxidative stress (OS) markers (iNOS and Hmox1) in the treated Npc mice group. Regarding the autophagic markers, we surprisingly found significantly reduced levels of the ratio LC3B-II/LC3B-I and a significant reduction of brain protein levels of lysosomal-associated membrane protein-1 (LAMP-1) in Npc mice treated group compared to non-treated. Lipid profile analysis showed a significant reduction in lipid storage in the liver and some slight changes in brain tissue in treated Npc mice compared to non-treated groups. Thus, Our results suggest that the pharmacological inhibition of sEH ameliorates most of NPC’s characteristic traits in mice, demonstrating that sEH can be considered a potential therapeutic target for this condition.
Treatment With a Probiotic Mixture Containing Bifidobacterium Animalis Subsp. Lactis BB12 and Enterococcus Faecium l3 for the Prevention of Allergic Rhinitis in Children: A Randomized Controlled Trial
Authors: Anania Caterina , Di Marino Vincenza Patrizia , Olivero Francesca , De Canditiis Daniela , Brindisi Giulia , Iannilli Federico , Spagnoli Alessandra , De Castro Giovanna , Zicari Anna Maria , Duse Marzia
Published: March 2021

BACKGROUND: Probiotics may prevent the allergic response’s development due to their anti-inflammatory and immunomodulatory effects. The aim of this study is to determine if the prophylactic treatment with a mixture of Bifidobacterium animalis subsp. Lactis BB12 and Enterococcus faecium L3, would reduce symptoms and need for drug use in children with allergic rhinitis (AR). METHODS: The study included 250 children aged from 6 to 17 years, affected by AR. Patients were randomly assigned to the intervention group (117) or to the placebo group (86). Patients of the intervention group, in addition to conventional therapy (local corticosteroids and/or antihistamines), were treated, in the 3 months preceding the development of AR symptoms, with a daily oral administration of a probiotic mixture containing the Bifidobacterium animalis subsp Lactis BB12 DSM 15954 and the Enterococcus faecium L3 LMG P-27496 strain. Nasal Symptoms Score(NSS) was used to evaluate AR severity before and after the treatment with probiotics or placebo. RESULTS: 96% of the patients in the intervention group showed a significant decrease in their NSS after the probiotic treatment as well as a decrease in the intake of pharmacological therapy. GPower software was used to calculate the test power. Given the probability of error α = 0.05, the total sample size n = 117 and the effect size ρ = 2.0651316, the power of the test is 1 - β = 1. CONCLUSIONS: When administered as a prophylactic treatment the mixture of BB12 and L3 statistically decrease signs and symptoms of AR and reduces significantly the need of drugs.
Optimal Power Flow Considering Intermittent Solar and Wind Generation using Multi-Operator Differential Evolution Algorithm
Authors: Hossain Md Alamgir , Sallam Karam M. , Elsayed Seham S. , Chakrabortty Ripon K. , Ryan Michael J.
Published: March 2021

In this paper, a multi-operator differential evolution algorithm (MODE) is proposed to solve the Optimal Power Flow (OPF) problem and is called MODE-OPF. The MODE-OPF utilizes the strengths of more than one differential evolution (DE) operator in a single algorithmic framework. Additionally, an adaptive method (AM) is proposed to update the number of solutions evolved by each DE operator based on both the diversity of population and quality of solutions. This adaptive method has the ability to maintain diversity at the early stages of the optimization process and boost convergence at the later ones. The performance of the proposed MODE-OPF is tested by solving OPF problems for both small and large IEEE bus systems (i.e., IEEE-30 and IEEE-118) while considering the intermittent solar and wind power generation. To prove the suitability of this proposed algorithm, its performance has been compared against several state-of-the-art optimization algorithms, where MODE-OPF outperforms other algorithms in all experimental results and thereby improving a network's performance with lower cost. MODE-OPF decreases the total generation cost up to 24.08%, the real power loss up to 6.80% and the total generation cost with emission up to 8.56%.
Aktivitas Antioksidan dan Screening Fitokimia Kulit Bligo (Benincasa hispida)
Authors: Hakiki Dini Nur , Fauziyyah Athiefah , Wijanarti Sri
Published: March 2021

Bligo (Benincasa hispida) merupakan tanaman yang tumbuh di daerah tropis dan subtropis. Buah bligo mengandung senyawa-senyawa aktif antara lain flavonoid, glikosida, karoten, vitamin, mineral, dan asam uronat. Penelitian di bidang farmakologi telah mengungkapkan bahwa buah bligo memberikan efek kesehatan, antara lain antidepressant, ansiolitik, antioksidan, antiinflamatori, diuretik, antidiabetik, dan antimikrobia. Namun penelitian di Indonesia mengenai kulit bligo masih sangat terbatas. Penelitian ini bertujuan untuk melakukan aktivitas antioksidan dan screening fitokimia pada kulit bligo. Kulit bligo dikeringkan kemudian digiling menjadi bubuk ukuran 100 mesh. Pengujian yang dilakukan adalah uji aktivitas antioksidan menggunakan DPPH, dan uji screening fitokimia kualitatif menggunakan LC-MS/MS QTOF. Aktivitas antioksidan pada kulit bligo adalah kelas medium dengan nilai IC50 6,91 mg/mL. Dari hasil analisis LC-MS/MS QTOF diketahui bahwa kulit bligo mengandung 36 senyawa, dengan 5 senyawa dominannya adalah adenosin; polidatin; 7-(4-hidroksi-3-metoksifenil)-l-(4-hidroksifenil)-4E,6E-heptadien-3-on; morasin C; dan kushenol S. Hasil karakterisasi yang diperoleh menunjukkan bahwa kulit bligo berpotensi sebagai senyawa aktif.

Antioxidant Activity and Phytochemical Screening of Peel Bligo (Benincasa hispida). Bligo (Benincasa hispida) is a plant that grows in tropical and subtropical regions. Bligo fruit contains active compounds such as flavonoids, glycosides, carotene, vitamins, minerals, and uronic acid. Research in the field of pharmacology has revealed that bligo fruit has health effects, including antidepressants, anxiolytics, antioxidants, anti-inflammatory, diuretics, antidiabetic, and antimicrobials. However, research on bligo peel is very limited. This study aims were to carry out antioxidant activity and phytochemical screening of bligo peel characteristics. Bligo’s peel was dried and ground into 100 mesh powder. Then antioxidant activity test using DPPH, and qualitative phytochemical screening test using LC-MS/MS QTOF were conducted. The bligo peel is medium class of antioxidant activity with IC50 value was 6.91 mg/mL. From the results of LC-MS/MS QTOF analysis it was known that bligo skin contained 36 compounds, with 5 dominant compounds, namely adenosine; polydatin; 7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-4E, 6E-heptadien-3-one; moracin C; and kushenol S. The results of the characterization showed that bligo skin has the potential as a source of active compounds for further utilization.
Melanotic Neuroectodermal Tumor of Infancy in the Ulna of an Infant: A Very Rare Tumor
Authors: Kovoor Cherry Cheriyan , Jayakumar R. , Manjunath Samarth
Published: March 2021

Case:

A 4-month-old boy presented with a nontender swelling of the right proximal forearm of 2 months' duration. Radiological evaluation showed lytic lesion surrounded by sclerotic bone in the ulna with soft-tissue extension. Histopathological examination showed tumor of round and epithelioid cells containing melanin, interpreted as melanotic neuroectodermal tumor. The patient underwent a wide excision of the shaft of the ulna with creation of radioulnar synostosis. There is no recurrence 6 years after surgery.

Conclusion:

Melanotic neuroectodermal tumor is rare in the appendicular skeleton and has to be differentiated from other round cell tumors and osteomyelitis. As far as we know, this is the first reported case in the ulna.
Detection of bacteriophages and cyanophages for water quality control of a water supply system in Amazônia
Authors: Gois Bruna Verônica Azevedo , Pinheiro Kenny da Costa , Nogueira Wylerson Guimarães , Aragão Andressa de Oliveira , Queiroz Ana Lídia Cavalcante , Silva Artur , Folador Adriana Carneiro , Ramos Rommel
Published: March 2021

Background: Despite the importance of understanding the ecology of freshwater viruses, there are not many studies on the issue when compared to marine viruses. The microbiological interactions that occur in these environments are still poorly known, especially between bacteriophages and their host bacteria, as well as between cyanophages and cyanobacteria. Lake Bologna, from Belém, capital of the Brazilian State of Pará, is a source of water that supplies the city and its metropolitan region, yet it remains unexplored regarding the contents of its virome and viral diversity composition. Therefore, this work's main aim is to clarify in terms of taxonomic diversity the species of DNA viruses that are present in this lake, especially bacteriophages and cyanophages, since they can act both as transducers of resistance genes and reporters of water quality for human consumption. Results: For this work, we used the metagenomic sequencing data generated by Alves et al. (2020), and we analyzed it at the taxonomic level using the tools Kraken2, Bracken, and Pavian; later, the data was assembled using Genome Detective, which performs assembly of viruses. The results observed in this work suggest the existence of a widely diverse viral community and an established microbial phage regulated dynamics in the Lake Bolonha. Conclusions: This work is the first-ever to describe the virome of Lake Bolonha using a metagenomic approach based on high-throughput sequencing, as it contributes to the understanding of water-related public health concerns regarding the spreading of antibiotic resistance genes and population control of native bacteria and cyanobacteria.
Open porous morphology evolution in poly (butylene succinate)/chitin nanocrystal nanocomposite foams
Authors: Fu Hai , Yin Dexian , Wang Tianhao , Gong Wei , Zhou Hongfu
Published: March 2021

In recent decades, biodegradable polymeric open-porous foams have been engaging increasing interests owing to their biodegradability, porosity and biocompatibility. In this work, biodegradable poly (butylene succinate) (PBS)/chitin nanocrystals (ChNCs) nanocomposite foams with open porous structure were successful fabricated by a solid-state batch foaming method. ChNCs were obtained from chitin by using sulfuric acid treatment and then introduced into PBS. The incorporation of ChNCs had a positive effect on the crystallization behaviors, melt viscoelasticity and thermal stability of diverse PBS specimens. Compared with the change of foaming temperature, the addition of ChNCs would cause a prominent influence on the open porous structure of diverse PBS foams. The probable explanation was that during the foaming process, the spherulites and/or ChNCs as the hard region in PBS could be served as pore wall and the amorphous area as the soft region was acted as pore, leading to open porous PBS foams. The reported strategy in this work could provide the guidelines to regulate and control open porous foams in other semi-crystalline polymer matrices.
Effects of selected Taiwanese endemic plants on anti-lipid peroxidation and antibacterial activities against clinically isolated extended-spectrum-β-lactamase producing Klebsiella pneumoniae and Escherichia coli
Authors: Tsai Po-Wei , Lin Pei-Chin , Yang Ling-Ling , Wu Ming Shun
Published: March 2021

It has been a challenge for many clinicians to treat a complicated extended-spectrum-β-lactamase (ESBL) producing Klebsiella Pneumoniae (Kp) and Escherichia coli (E. coli) infection due to widespread antibiotic abuse with renal damage as one of its common side effects. Therefore, this study aimed to assess the antibacterial activity of extracts from several Taiwanese folk medicinal plants against ESBL- Kp and E. coli. with renal protecting ability against lipid peroxidation (LPO) on mice kidney mitochondria. Preliminary antibacterial activities of ethanol extracts from twenty (20) Taiwanese folk medicinal plants were measured by agar-dilution method against standard ESBL strains of E. coli (ATCC 25922, ATCC 35218) and Kp (ATCC 23856, ATCC 700603). Rhus semialata var. roxburghiana DC. (RSR) exerted the most inhibitory effect and then further extracted with n-hexane, ethyl acetate, acetone, ethanol, and water, respectively. Each extract also evaluated against the four standard ATCC microorganisms. Their MIC50, MIC90, and time kill assay were adapted with detecting the maximum inhibitory activities and the antibacterial spectrum range of each extract was measured against twenty-four (24) kinds of microbes. Which were used including gram-positive, gram-negative bacteria and fungus by agar dilution method. Finally, renal protective ability was detected inhibitory effect of ferrous induced lipid peroxidation on mice mitochondria. Among 20 Taiwanese folk medicinal plants tested, Rhus semialata var. roxburghiana DC. (RSR) exhibited maximum inhibition against clinical ESBL-producing Kp and E. coli strains with acetone extracts showing MIC50/MIC90 values at 1000 µg/mL, the course of antimicrobial action was bacteriostatic and with inhibitions to all 24 kinds of microbial including Gram positive and negative bacteria and fungi. Furthermore, result of thiobarbituric acid reactive substances (TBARS) assay from this extract showed high lipid peroxidative (LPO) protective capability on mice kidney mitochondria (IC50: 29.29 ± 0.35µg/mL). RSR acetone extract, with its maximum activity against clinical isolated ESBL-producing Kp and E. coli, antimicrobial effect against other wide spectral range bacteria and relatively high LPO protective ability on mice kidney mitochondria, is a potential source, albeit further studies have yet to be conducted, to develop an antimicrobial drug against ESBL-Kp and E. coli.
Risk Factors For Progression Following Corneal Collagen Crosslinking In Keratoconus
Authors: Saglik Ayhan , Özcan Gökçen , Uçakhan Ömür
Published: March 2021

Purpose: To assess risk factors for progression following corneal collagen crosslinking (CXL) in eyes with keratoconus. Methods: Charts of patients who developed progression following conventional CXL treatment (Dresden protocol) were retrospectively evaluated in two centers (Center 1, and Center 2). 871 eyes of a total of 676 patients were analyzed. Progression was defined as >1 diopter (D) increase in maximum keratometry (Kmax) readings compared to baseline. Results: Progression was noted in 20 eyes of 20 patients (progression rate 3%). The mean age of the patients was 17.65 ± 5.76 (11–34) years and the mean follow-up following CXL was 36.70 ± 25.72 (12–84) months. The gender distribution was 13 (65%) females, and seven (35%) males. Four eyes (20%) had mild, 13 eyes (65%) had moderate, and three eyes (15%) had severe keratoconus at baseline. Fifteen eyes (75%) had allergic conjunctivitis and 20 eyes (100%) reported eye-rubbing. Cone location was central in 17 (85%) eyes and peripheral in 3 (15%) eyes. A mean of 2.21 ± 1.30 D (1.00 – 5.30 D) steepening was determined at Kmax 6 to 82 months following CXL treatment. Conclusions: Progression rate was found to be higher in the patients under the age of 17 years, female gender, allergic conjunctivitis, high preoperative Kmax (>57 D), thin corneas (<430 µm) . The majority of progressive patients were central cone and moderate keratoconus.
Cantilever self-excited with a higher mode by a piezoelectric actuator
Authors: Zhou Keyu , Urasaki Shinpachiro , Yabuno Hiroshi
Published: March 2021

The sensitivity of vibration-type sensors can be improved using a higher resonating frequency of a cantilever resonator. Resonance in such systems can be achieved using a self-excited oscillation, which overcomes the difficulty of using an external excitation in viscous environments. To enhance the sensitivity of cantilever resonators, several groups have proposed ways to increase the natural frequency of the first mode by changing the cantilever geometry. However, the sensitivity can be further improved by using a self-excited oscillation with a higher mode in addition to the geometry-changing technique. In this study, we present a method to realize this goal. We perform a nonlinear analysis of the governing equation of a cantilever excited by a piezoelectric actuator. For each mode, we also clarify the dependence of the critical feedback gain on the location of a displacement sensor, the output of which is used for feedback control. With the aid of filters, we then devise a way to generate a self-excited oscillation with a higher mode associated with a desired higher natural frequency. Finally, we carry out experiments using a macrocantilever and report the observation of a self-excited oscillation with the second natural frequency, which is higher than the first natural frequency.
WITHDRAWN: Establishment and validation of a novel metabolism-related genesignature for predicting overall survival of patients with breast cancer
Authors: Li Jian , Liu Yang , Liu Fei , Tian Qiang , Li Baojiang , Wei Guangwei , Zhang Zongwang
Published: March 2021

Background: It is well known that Breast cancer is a heterogeneous disease. Although the current recurrence and mortality rate have been greatly improved, many people still suffer relapse and metastasis. Metabolic reprograming is currently considered to be a new hallmark of cancer. Therefore, in this study, we comprehensively analyzed the prognostic effect of metabolic-related gene signatures in breast cancer and its relationship with the immune microenvironment. Result: The metabolic gene signature may be an independent risk factor for BC both in the training and the testing set,the nomogram has a moderately accurate performance, and the C index was 0.757 and 0.728 respectively. The signature can reveal metabolic characteristics based on gene set enrichment analysis and at the same time monitor the status of TME. Conclusion: This gene signature can be used as a promising independent prognostic marker for BC patients, and can indicate the current status of TME, providing more clues for exploring new diagnostic and treatment strategies.
Sacred Groves: A Pattern of Zagros Forests for Carbon Sequestration and Climate Change Reduction
Authors: moradi Aiuob , Shabanian Nagi
Published: March 2021

Background

Rising atmospheric carbon dioxide has led to the global consequences of climate change. Biological carbon sequestration through vegetation and soils is one of the cost-effective ways to reduce this gas. Forests ecosystems are the most important carbon pools among terrestrial ecosystems and play a sustainable and long-term role in reducing climate change. Among forest ecosystems, sacred groves are less-disturbed and they can be a pattern of successful forest management for carbon sequestration and climate change reduction. In the present study, for the first time, the amount of carbon content in sacred grove and silvopastoral lands were investigated to determine the capacity of Zagros oak forests in carbon sequestration and climate change reduction. The aim of this study was to estimate the amount of carbon reserves in mentioned land-uses in order to obtain a systematic attitude towards management of these different land-use types and attain a suitable solution to counter the climate change crisis and ultimately sustainable environmental development.
Results

The results showed that each of the studied variables in the two studied land use is significantly different from each other. The mean of each of these biomass or carbon pools in silvopastoral is significantly lower than sacred groves. The results indicate that the common utilizations in the forests of the study area cause a significant reduction (P ≤ 0.01) in the forest biomass value and respective carbon content. Sacred grove currently absorbs 826.96 tons of carbon dioxide per hectare more than silvopastoral lands and this is a sign of high degradation in the forests of the study area.
Conclusions

According to the results obtained in this study, forest ecosystems that are protected against human intervention play a significant role in long-term carbon storage. Any interference with the natural conditions of the ecosystem has a significant negative impact on carbon reserves. Therefore, by selecting appropriate measures, local communities should be empowered to reduce their dependence on low incomes obtained from deforestation and conversion.
Mechanism Confirmation of Organofunctional Silanes Modified Water Glass/Polyurethane-Urea Composites for Remarkably Enhanced Mechanical Properties
Authors: Liang Yuntao , Gao Ao , Sun Yong , Tian Fuchao , Sun Weili , Lu Wei , He Zhenglong
Published: March 2021

Hybrid reinforced water glass/polyurethane-urea (WG/PU) composites mainly derived from low-cost WG and polyisocyanate are produced in the presence of 3-chloropropyltrimethoxysilane (CTS). The wettability of WG on PU substrate surface is significantly improved as CTS content increases from 0.0 wt% to 3.5 wt%. Furthermore, with 2.5 wt% of CTS optimal addition, the fracture surface morphology and elemental composition of the resulting WG/PU composites are characterized, as well as mechanical properties, chemical structure and thermal properties. The results indicate that the CTS forms multiple physical and chemical interactions with the WG/PU composites to induce an optimized organic-inorganic hybrid network structure thus achieving simultaneous improvement of compressive strength, flexural strength, flexural modulus and fracture toughness of the WG/PU composites, with the improvement of 12.9%, 6.6%, 17.5% and 9.7%, respectively. Moreover, the CTS in the WG/PU composites has a significant influence on the curing process of the WG/PU composites by accelerating the rate of mass and heat transfer. Additionally, a reasonable mechanism explanation for CTS modified WG/PU composites is confirmed.
Identifying Predictors of Peripheral Intravenous Catheter Failure Using a Novel Combination of Clinical and Ultrasonographic Assessments
Authors: Bahl Amit , Johnson Steven , Mielke Nicholas , Karabon Patrick
Published: March 2021

Objective:Peripheral intravenous catheter (PIVC) failure occurs frequently, but the underlying mechanisms of failure are poorly understood. We aim to identify factors that predict premature PIVC failure.Methods:We conducted a single site prospective observational investigation at an academic tertiary care center. Adult emergency department (ED) patients who underwent traditional PIVC placement in the ED and required admission with an anticipated hospital length of stay greater than 48 hours were included. Ongoing daily PIVC assessments included clinical and ultrasonographic evaluations. The primary goal was to identify demographic, clinical, and PIVC related variables that predicted PIVC failure. Univariate and multivariate analyses were employed to identify risk factors for PIVC failure.Results:In July and August of 2020, 62 PIVCs were enrolled. PIVC failure occurred in 24 (38.71%) participants. Multivariate logistic regression demonstrated that the presence of subcutaneous edema [AOR 8.29 (1.50, 45.8) p = 0.0153], an above average neutrophil to lymphocyte (N:L) ratio [AOR 4.63 (1.06, 20.3) p = 0.0422], and the administration of an irritant/vesicant [10.3 (1.46, 72.6) p = 0.0.192] were associated with increased likelihood of premature PIVC failure. Conclusions:PIVC failure is related to clinical and ultrasonographic variables associated with inflammation: elevated N:L ratio, use of caustic medications, and presence of subcutaneous edema on ultrasound. Reducing inflammation of the vein may lead to better PIVC survival outcomes. Further large-scale randomized controlled trials are needed to validate and build upon the concepts in this study.
Enhancement of Antibacterial and Mechanical Features of Glass Ionomer Restoration by Adding ZnO Nanoparticles Prepared by PLAL: In Vitro Study
Authors: Jaber Ghufran. S. , khashan khawla , Abbas Maha Jamal
Published: March 2021

The objective of this manuscript was to study the antibacterial and mechanical effect on composition ZnONPs-Glass Ionomer restoration. Zinc oxide nanoparticles prepared by laser ablation in liquid at different concentrations. After that, the glass ionomer was adding in calculated amount to get homogenous composition. The physical properties of resulted NPs were examined by FTIR, XRD, TEM, and AFM. The Antibacterial activity against streptococcus mutant and compressive strength were also measured. The result of the FTIR spectrum confirms the formation of the Zn-O bond. XRD pattern shows peaks at 28..55°, 31.21° and 42.70°, correspond to the (100) (101) and (102) crystal planes of cubic Zinc Oxide structure. TEM image exhibits spherical and homogenous ZnO nanoparticles with particle size <50nm. Also, the result shows a significant increase in the antibacterial property of ZnO-GI with good modifying the mechanical properties. Thus adding ZnO nanoparticles to glass ionomer restoration can be considered as a better alternative to conventional GI.