bluuebunny/crossref_metadata_2025 huggingface dataset:
Catalizadores bifuncionales basados en mezclas de porfirinas metálicas como componentes de cátodos de baterías de litio-oxígeno
Authors:   , Ocampo Gerardo Roberto
Published: April 2023

La reacción de reducción de oxígeno (ORR) y la reacción de evolución de oxígeno (OER) son dos reacciones de gran interés tecnológico, muy importantes para garantizar la eficiencia de dispositivos electroquímicos, involucradas en celdas de combustible, electrólisis del agua y en baterías de Litio- oxígeno. No obstante, las cinéticas de dichos procesos son demasiado lentas y por lo general se requiere el empleo de electrocatalizadores adecuados que mejoren la performance de ambas reacciones (catalizadores bifuncionales o duales). En este contexto, las porfirinas de Fe y Co han demostrado tener buenas propiedades para catalizar la ORR y OER, respectivamente, a menores sobrepotenciales, resultando excelentes candidatos a tener en cuenta. En este trabajo de tesis se emplean porfirinas metálicas soportadas sobre sustratos conductores para evaluar su acción catalítica en medio alcalino. Partiendo de sales de diazonio de porfirinas (con y sin centro metálico), las mismas fueron unidas a sustratos de Au y C por electrografting y por evaporación en condiciones de ultra alto vacío. En todos los casos las películas obtenidas fueron debidamente caracterizadas por técnicas de superficie como AFM, XPS, EQCM, etc. Para finalmente evaluar la actividad catalítica de las mismas para ambas reacciones de interés (ORR y OER). A lo largo de los capítulos experimentales se describen los procesos sintéticos de las sales de diazonio, el crecimiento de multicapas y monocapas controlado mediante la adición de un atrapador de radicales libres a la solución de electrografting, la formación de películas orientadas de manera diferente y la formación de películas de porfirinas mixtas que podrían actuar como catalizadores duales. En todos los casos se evalúa y compara la performance electrocatalítica para las reacciones de evolución y reducción de oxígeno. Se elaboraron conclusiones a partir de los resultados obtenidos permitiendo así visualizar las perspectivas y pasos a seguir con las investigaciones.
Quo vadis, piacgazdaság? Fenntarthatósági és értékrendi kihívások, lehetséges válaszok
Authors: Kocziszky György
Published: April 2023

Az elmúlt fél évszázad során a piacgazdaságok működésének elméleti alapjául szolgáló mainstream közgazdaságtan paradox módon a valóságtól elszakadva, értéksemleges modellekben gondolkodott. Ezek erőltetett absztrakciója, továbbá a gazdaságpolitikában uralkodóvá vált dereguláció és a liberalizáció következtében a piacok nem tudták megfelelően kezelni a válságokat, illetve maguk is előidézőivé váltak azoknak. A szerző jelen tanulmányában azt állítja, hogy van megoldási lehetőség: ez a fenntartható piacgazdaság, amelynek alapfeltétele az értékközpontúság reintegrálása a piaci folyamatokba. Azaz olyan paradigmaváltásra van szükség, amelynek középpontjában a fenntarthatóság áll. De a fenntarthatóság mindaddig csak szóvirág, amíg nem tudatosul, hogy a társadalmi, gazdasági mozgásterünk korlátos, vagyis nem mindent tehetünk meg, amire egyébként volna lehetőségünk. Ennek ismeretében bizton állítható, hogy a 21. században csak azok a nemzetek lesznek sikeresek, amelyek megtalálják a fenntartható piacgazdasághoz vezető utat, és képesek is azon járni. A szerző által felvázolt modell ennek a gondolatnak a megvalósítási irányaira tesz javaslatot.
The phenomenon of stigmatization: the case oh delinquency and repeated deeds in Tunisian society
Authors: Tej Ramzi
Published: April 2023

The violations of regulatory rules, martial and religious laws, and social mores were among the reasons that led to the spread of various social phenomena. The latter contributed to social communication disorder and created immense abysses within societies such as immorality, violence and delinquency. Based on the explanatory theories of criminology or criminal sociology, the stigma of deviance was classified as a psychosocial disorder that the stigmatized suffers from, which had been confirmed by various researches starting from 1930s till 1950s. However, sociologists and experts in historical anthropology surpassed the concepts of linguistic terms, which were chiefly investigated by psychologists, to examine the features of stigmatization from a scientific perspective. Through the discussion of stigmatization, this research examines the key implications of stigma in relation not only to individuals but also to communities. It also investigates the reasons that lead some sectors of society to renounce and marginalize the stigmatized individual despite his efforts to go out the indictment division that crippled him and to reintegrate within his society.

عدّ الخروج عن الأطر التّنظيميّة، وقوانين الأحكام العرفيّة والشّرعيّة، والعوائد المجتمعيّة من أسباب تفشّي عدّة ظواهر اجتماعيّة ساهمت في خرق أسس التّواصل، وخلقت هوّة سحيقة في صلب المجتمعات الحاضنة لتلك الظّواهر، ولعلّ الانحلال الأخلاقي، وتنامي أشكال العنف والانحراف هما أبرز النّتائج المتمخّضة عنها. ويتنزّل الوصم الانحرافي اِستنادا إلى النّظريّة التّفسيريّة في علم الإجرام، أو علم الاجتماع الجنائيّ ضمن خانة الخلل النّفسيّ الاجتماعيّ الذي يعاني منه الموصوم بالانحراف، وهو ما أكّدته عديد الأبحاث التي خصّصت حيّزا كبيرا من اهتمامها لدراسة الظّاهرة منذ ثلاثينيّات القرن العشرين حتّى منتصف القرن ذاته، بيد أنّ علماء الاجتماع تجاوزوا مفاهيم المصطلحات الّلغويّة التي أشبعت بحثا مع المتخصّصين في علم النّفس للخوض في صفة الوصم من النّاحية العلميّة. وحاول هذا البحث من خلال التّطرق إلى ظاهرة الوصم، الخوض في أهمّ التّداعيّات المترتّبة عنها سواء في علاقة بالأفراد، أو في علاقة بالمجموعات، والأسباب التي دفعت بعض شرائح المجتمع إلى نبذ الموصوم وتهميشه رغم محاولاته الخروج من دائرة الاتّهام التي أحاطت به، والاندماج من جديد في المجتمع المنتمي إليه رغم المضايقات المسلّطة عليه.
Parentalidad positiva: afecto, control y justicia del trato parental hacia díadas fraternas y su relación con los problemas socio-emocionales de los hijos adolescentes
Authors: Posada David , López-Larrosa Silvia
Published: April 2023

Cuando se estudia la parentalidad positiva, no suele tenerse en cuenta la percepción que los hijos/as tienen del comportamiento diferencial de sus padres y madres hacia cada hijo/a. En este trabajo, los objetivos eran analizar las diferencias en problemas externalizantes e internalizantes de los hermanos/as, así como la relación entre afecto, control y justicia del trato de padres y madres, el ajuste entre afecto y control y los problemas externalizantes e internalizantes de hermanos/as adolescentes. Participaron 111 parejas de hermanos/as adolescentes (N = 222), en las que el/la mayor tenía una media de 15,18 años y el/la menor tenía una media de 12,85 años. Se usaron las subescalas de afecto y control del Sibling Inventory of Differential Experience (SIDE), se crearon ad-hoc medidas de la justicia del trato de los progenitores y se usó el Strengths and Difficulties Questionnaire (SDQ) para evaluar los problemas internalizantes y externalizantes de los hijos/as. Los resultados indicaron que los hijos/as mayores tenían una media más elevada en problemas internalizantes y los menores en problemas externalizantes. Cuanto más elevado era el control materno de los hijos/as mayores comparado con los/las menores, más problemas externalizantes e internalizantes tenían los/las mayores. En los hijos/as mayores, el ajuste afecto-control de padre y madre se relacionó con menos problemas externalizantes, y el ajuste afecto-control de las madres se relacionó con menos problemas internalizantes. El trato materno percibido como más justo se relacionaba con menos problemas internalizantes y externalizantes de los hijos/as menores. El ajuste afecto-control del padre se relacionó con menos problemas internalizantes de los hijos/as menores. Estos resultados contribuyen al conocimiento del impacto diferencial del comportamiento parental positivo cuando tienen dos hijos/as adolescentes.
TAHLÎL AL KITÂB AL MADRASY LI AL LUGHAH AL ‘ARBÎYAH LI AL SHAFFI AL SÂB’I LI WAZÂRAH AL SYÛN AL DÎNÎYAH ‘ÂM 2020 ‘ALA NAZRÎYAH I’IDÂD AL MAWÂD AL T’ALÎMÎYAH LI RUSYDI AHMAD TU’AIMAH
Authors: Khair Miftahul , Firmansyah Muh. Guntur , Rosyidi Abdul Wahab , Muhaiban Muhaiban
Published: April 2023

In this study, we discussed the results of the analysis of the Arabic language textbook for the Ministry of Religious Affairs seventh grade in 2020 according to the theory of preparing educational materials for Rushdi Ahmed Tuaima—the basic. The researcher used analytical research, a qualitative approach, type of document or textual study (document study). They examined the results of this analysis that the number of its pages is 144 pages on average, each lesson contains 22 pages, this book has six errors in the formation of letters and the typographical errors in this book are two, and the number of lessons in the book for teaching the Arabic language for the seventh grade is less than The number of classes expected to be taught. The language level in this textbook is the beginner level, and the proposed duration of the book is sufficient to teach the book in one year. We found that the teacher in some language skills still plays a decisive role in the learning process, so communication channels must be diversified to enhance the learning and teaching experience. This textbook included various linguistic situations from vocabulary, texts, dialogue, composition, and listening. Also, various activities can help students improve their language skills and prepare them to deal effectively with Arabic in daily life.
On the renewal of fishing at the Ivankovskoye reservoir
Authors: Goryachev D. V. , Nikitenko A. I. , Amelin M. Y. , Karavaeva M. S. , Kudinov M. U. , Gvozdarev D. A. , Butorina A. P.
Published: April 2023

Information on the state of commercial stocks of the fish population of the Ivankovo reservoir from 1980 to the present is presented. According to our data, the total commercial fish stocks in the Ivankovo reservoir in comparison with the 1980s and 1990s decreased by almost 1,000 tons. Over the past 5 years, they have been in the range of 2245–2808 tons. The closure of industrial fishing in 2007 led not to an increase, but to a decrease in fish stocks, due to a decrease in the rate of their linear and weight growth, deterioration of exterior and commercial qualities. The material damage caused by the closure of industrial fishing at the Ivankovsky reservoir since 2007 has been determined. To determine the material damage caused by the closure of industrial fishing at the Ivankovsky reservoir, retail prices for 21 types of fish were determined. The resulting value for each type of fish was correlated with the volume of fish that was not caught due to the absence of fishing in the period from July 2007 to 2022. Data on catch volumes in the Ivankovo reservoir are taken from the Orders on approval of the total allowable catches and recommended catch of aquatic biological resources in 2007–2022. Over the past 15 years, the possibility of catching almost 7.4 thousand tons of fish has been lost, which in monetary terms is 1,103 million rubles.
Endolysins of bacteriophages
Authors: Barkova Irina A. , Izhberdeeva Margarita P. , Sautkina Anastasiya A.
Published: April 2023

Bacteriophage endolysins are a biologically active substances that play a specific role in the release of phage progeny by degrading the peptidoglycan of the host bacterium. In the light of antibiotic resistance, endolysins are considered as alternative therapeutic agents because of their exceptional ability to target bacterial cells.
Aim summarization of the data on the biology, structure, mechanisms of action of bacteriophage endolysins, as well as on preparations based on them, which are at different stages of research.
The results of studies of bacterial endolysins over the past 20 years were searched using the Internet resources PubMed, Web of Science, Scopus in English for the keywords: lysin, bacteriophages, holin, antibiotic resistance.
The analysis of literature data showed that the structure of phage endolysins of Gram-positive and Gram-negative bacteria differs from each other and reflects differences in their architecture due to variation in the cell wall composition of these two major bacterial groups. Depending on the cleavable bond in peptidoglycan, endolysins can be divided into at least five different groups: glycosidases (two groups aminidases and muramidases), endopeptidases, specific amidogyrolases, and lytic transglycosylases. To date, endolysins effective against a number of pathogens have been studied, including Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae, Staphylococcus aureus, Mycobacterium spp., Pseudomonas aeruginosa, etc. A number of studies have shown the therapeutic potential of endolysins in combating antibiotic-resistant infections.
Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West Russia
Authors: Lyalina Liudmila V. , Kholopov Dmitry V. , Yazenok Arkady V. , Khizha Valentin V. , Topuzov Eldar E. , Kasatkin Evgeny V. , Goryaev Evgeny A. , Zadorkina Tatiana G. , Molchanova Zhanna R.
Published: April 2023

Introduction. The leading role of the human papillomavirus in the etiopathogenesis of malignant neoplasms of some localizations is generally recognized. Vaccines that are used in the world and in Russia for the prevention of papillomavirus infection create the basis for the elimination of diseases associated with the human papillomavirus in the future.
The aim of the study is to determine the regional, gender and age-specific features of cancers associated with the human papillomavirus to substantiate the development of a unified system of epidemiological surveillance and vaccination.
Materials and methods. The retrospective epidemiological analysis of the incidence of cancers associated with the human papillomavirus and mortality due to these neoplasms in the regions of the North-Western Federal District of Russia in 20112020 was carried out based on data from Statistic Form 7 "Information on malignant neoplasms" and the Population cancer Registers of St. Petersburg (13,117 cases), Leningrad region (3204 cases) and the Kaliningrad region (2898 cases).
Results. In the structure of cancers associated with the human papillomavirus in St. Petersburg, Leningrad and Kaliningrad regions, more than 90% of men had tumors of the oral cavity, oropharynx and larynx, more than 60% of women had cervical cancer. Regional and age-specific features of the incidence of cervical cancer and mortality from this pathology have been established. Statistically significant differences in the incidence of cancer of the head and neck, anus and anal canal in different age groups of the male and female population were revealed.
Conclusion. As a result of the study, regional, gender and age-specific features of the incidence of human papillomavirus-associated malignant neoplasms in the North-West of Russia were established. These data should be used to develop a system of epidemiological surveillance of papillomavirus infection and vaccination program.
Relation of Pneumonia with Some Socioeconomic Factors in Children Under Five Years Old in Al-Najaf Governorate.
Authors: Abdul-Redah Muhsin Fulath
Published: April 2023

Background: Pneumonia remains the leading killer of young children despite the availability of: simple, safe, effective and inexpensive interventions to reduce its capacity to kill.
Objective: The aim of the study is to tracing of pneumonia disease in relation with some socioeconomic factors in children under five years.
Methodology: A descriptive study was carried out in Al-Zahraa and Al-Hakeem Hospital for the period of 1/10/2012 to 28/3/2013. A purposive (non probability) sample of (100) patients was included. Questionnaire was constructed for the purpose of the study, data were collected through the application of the questionnaire and interview technique. Data were analyzed through descriptive statistical approach ( pie and bar chart) and inferential statistical approach (t-Test) by using of (SPSS version 17).
Results: The study results indicated that the highly percentage of pneumonia patients was in age group of (0-1 year), (83 %) and it gave a highly statistical significant deference (HS=P<0.001). The highly percentage of pneumonia patients (86%) was in low income more than another incomes and it gave a highly statistical significant deference (HS=P<0.001). The highly percentage of causes of pneumonia was bacteria (90%), in comparison with another causes and it gave a highly statistical significant deference (HS=P<0.001). The highly percentage of pneumonia patients was in male (62%), than female (38%), and it gave a statistical significant deference (H=P<0.05). The highly percentage in distribution of pneumonia patients was in urban area (91%), than rural area (9%), and it gave a highly statistical significant deference (HS=P<0.001). The highly percentage of pneumonia occurrence was in a history of family smoker (30%, 38%) respectively, than non smoker (32%) and it gave a statistical significant deference (H=P<0.05).
Conclusions: pneumonia was common in the following statuses:- age group of ( 0-1 year), in low income, in bacterial infection, and urban area. While pneumonia was less common in the following statuses:- between gender and effect of cigarette smoking.
Recommendation: Strengthening of pneumonia health care to make its reaches to the majority of Iraqi mothers through the following : Training of doctors and medical workers and use the mass media as a health education about the disease.
The Relation-Ship Between Anti-Thyroidal Peroxidise Antibodies (TPO-Abs) and Thyroid Hormones (T3, T4 and Thyroid Stimulating Hormone TSH) among Patients of Autoimmune Thyroid Disease (AITD).
Authors: Taresh Hashim Rahim , Al-Fatlawi Rawaa Behlul Majhul , Al-Juburi Salman Aziz
Published: April 2023

Objectives: This Study was designed to investigate the role of the auto antibodies against thyroid peroxidise (TPO-Abs) and thyroid Hormones (T3, T4, TSH) in pathogenesis of Autoimmune Thyroid Disease (AITD).
Methodology: Blood parameters of (90) individual who were attended to hormonal center at AlSadder Medical City, in the period of January 2013 to June 2013 were measured, which includes Triiodothyronine (T3), Thyroxine or Tetraiodothyronine (T4), Thyroid Stimulating Hormone (TSH) and auto antibodies of thyroid peroxidise (TPO-Abs), the biostatic use difference between the maximum and minimum values (range).
Results: the search results showed no significant increase in the rate of thyroid hormones (T3, T4, TSH) (p>0.2).
Conclusion: The auto antibodies of thyroid peroxidise has no rule in function of thyroid hormones.
Recommendations: Further studies with numerous sample are needed.
Isolation and Identification of Gram-Positive and Gram-Negative Bacteria from Infertility Patients in Tikrit City
Authors: Karim Furat Latif , Ahmed Muneef Saab , Al-Obeidi Mazen Anwar
Published: April 2023

The objectives of the current study were conducting a statistical study to find out the number of men with primary and secondary infertility, immune infertility, and unexplained infertility in the city of Tikrit. Isolation and identification of Gram-positive and Gram-negative aerobic bacteria, and the study of some patterns of sensitivity to antibiotics of the isolated bacteria. The results showed that the percentage of primary infertility was the highest among infertility diseases, as the percentage reached 57%, while the lowest percentage was for immunological infertility, as it amounted to 7%. While the percentage of secondary and unexplained infertility was 15% and 31%, respectively. About the bacteriological study, the results showed two types of isolates, single bacterial isolates (52%), mixed bacterial isolates (38%). Percentages of isolates from E. coli and Klebsiella spp. and Staphylococcus spp. and Streptococcus spp. were 100%, 12%, 18%, and 10%, respectively. E. coli showed total (100%) resistance to amoxicillin/clavulanic acid and ampicillin. 50% resistance to Nalidixic. Otherwise, Escherichia coli showed resistance of 40%, 20%, 60%, 20% and 50% to Imipenem, Amikacin, Gentamicin, Azithromycin and Cefepime respectively. Klebsiella showed total (100%) resistance to amoxicillin/clavulanic acid and ampicillin. 40% resistance to Nalidixic. Otherwise, Klebsiella spp. showed resistance of 20%, 10%, 10%, 40% and 20% to imipenem, amikacin, gentamicin, azithromycin and cefepime respectively. Staphylococcus aureus showed complete resistance to penicillin, oxacillin and cefoxitin. 10%, 0%, 30%, 30%, 0%, 90% and 50% are resistant to gentamicin, nitrofurantoin, erythromycin, azithromycin, rifampicin, trimethoprim and ciprofloxacin respectively. Streptococcus spp. completely resistant to penicillin, oxacillin and cefoxitin. 30%, 0%, 20%, 10%, 0%, 70% and 30% are resistant to gentamicin, nitrofurantoin, erythromycin, azithromycin, rifampicin, trimethoprim and ciprofloxacin respectively.
Highway Pavement Stabilization of Soil with Costus bracteatus Rowlee and Cement
Authors: Kennedy Charles , Theophilus Akinbuluma Ayodeji
Published: April 2023

The study investigated the performance of cement and bagasse ash composite as soil stabilizer. The bagasse ash was obtained from Costus bracteatus Rowlee. Lateritic soil samples collected along a newly constructed road in Rivers State, Nigeria were prepared and analyzed for effect of the composite stabilizer on maximum dry density (MDD), optimum moisture content (OMC), consistency limits, California bearing ratio (CBR) and unconfined compressive strength (UCS). The results revealed that swelling potential, volume change MDD, OMC, liquid limit (LL), plastic limit (PL) and plasticity index (PI) of the stabilized lateritic soil decreased with increasing proportion of cement-bagasse ash composite, while CBR (unsoaked and soaked soil samples) and UCS were with increasing proportion of cement-bagasse ash composite. This study established that the optimum proportion of bagasse ash is 8% and that inclusion of an appropriate proportion of bagasse ash in cement in soil stabilization would enhance the properties of soil suitable for road pavement. Therefore, Costus bracteatus Rowlee is recommended to be used in soil stabilization, particularly as composite material.
Antibacterial Activity of Ethanolic Leaves Extract of Andographis paniculata on Isolates of Salmonella spp. and Escherichia coli from Locally Processed Beverages in Umueze Nkanu West Local Government Area Enugu State Nigeria
Authors: Jaluchimike Iloputaife Emmanuel , Nkechinyere Mbah-Omeje Kelechi , Jacinta Aneke Chinwe
Published: April 2023

The microbial contamination of locally processed beverages has been familiar among microbiological researchers who have repeatedly implicated them as the major cause of endemics due to poor processing. However, due to antimicrobial resistance and the need to discover new antimicrobial plants, Antibacterial activity of ethanolic leaf extracts of Andographis paniculata against isolates of Salmonella spp. and Esherichia coli from zobo and soya milk was studied. Andographis paniculata leaves were collected randomly from a local farm in Emene Enugu East L.G.A Enugu State. The leaves samples were identified morphologically, washed, air dried at room temperature and milled into powder. 39.7 g of the powder was macerated with ethanol during the extraction process. Phytochemical analysis was carried out on the extract and result showed that Saponins, Tanins, Flavanoids, Phenols, Steriods were present with Flavanoids and Saponins being in higher concentration, while Terpernoids, Alkaloids and Glycosides were absent. The zobo and soya milk samples were diluted using 10-fold serial dilution method and introduced into the already prepared MacConkey and Salmonella Shigella Agar for incubation. Isolates from zobo and soya milk were characterized, biochemically and morphologically and were identified as E. coli and Salmonella spp. Antibacterial activity of ethanolic leaf extracts of A. paniculata against E. coli and Salmonella spp. was determined using agar well diffusion method, and result showed that there was no antibacterial activity of ethanolic leaf extracts of A. paniculata against E. coli and Salmonella spp. However, absence of Terpernoids, Alkaloids and Glycosides exhibited non-comparable activity with the positive control (ciprofloxacin).
Medic-Aide: Developing a Medic Specific Staff Support Service in Palliative Care
Authors: Hussain Feryad A. , Kingsley Marc , Midgley Corinna
Published: April 2023

Objective: A pilot project and service evaluation to identify the benefits of offer medical staff psychological supervision to support them in a) managing patient distress and b) self –care. Methods: A fixed model of supervision was offered with pre and post outcome measure in the form of a questionnaire. Results: Overall the feedback across the service as a whole offered positive feedback in terms of the goals as above. Additional service developments and service extension considerations were also offered for future groups. Conclusion: Although the feedback was offered from a very small pilot group, the groups has shown benefit and continues to be offered and reviewed.
Posterior Reversible Encephalopathy after Scorpion Envenomation, Two Cases with Review of the Literature
Authors: Tadsaoui Samira , Nouri A. , Faiz S. , Zouita I. , Basraoui D. , Jalal H.
Published: April 2023

Posterior reversible encephalopathy (PRES) is a clinico radiological syndrome, which manifests itself by headaches, confusion, consciousness disorders or during a sudden rise in blood pressure but can be seen in other circumstances, such as during an immune reaction or a systemic infection. Its mechanism is explained by a lesion of the blood-brain barrier leading to a reversible vasogenic edema. The scarcity of sympathetic innervation of the posterior cerebral territories explains its usual localization. We report two cases of a 5 and 18 years old girl who presented with tonic-clonic seizures following a scorpion bite. An emergency brain MRI was performed, showing bilateral signal abnormalities of the posterior cortico-subcortical territories and basal ganglia, compatible with an atypical PRES syndrome. The diagnosis of PRES syndrome complicating a scorpion bite was retained.
Outcome of Heart Rate and Blood Pressure of a Patient after Successful Coronary Angioplasty and Stenting
Authors: Kawsar Dr. Syeda Masuma , Bhuyan Dr. Amirul Islam
Published: April 2023

Background: When left main coronary artery stenosis is significant, bypass surgery is the recommended treatment option. An alternate therapy, angioplasty with stenting, has been recommended by the outcomes of many multicenter studies. Objective: In this study our main goal is to evaluate the outcome of Heart Rate and Blood Pressure of a Patient after Successful Coronary Angioplasty and Stenting. Method: This cross-sectional study was carried out at tertiary hospital from January 2021 to January 2022. Where 100 patients stent implantation was carried out both men and women aged 69±8 years (range, 50­85 years) with serious LMCA lesions were included. Results: During the study, 55% were belonging to 50-60 years age group and 75% were male. 55% had hypercholesteremia, 57% had atrial hypertension, 55% diagnostics angiography 52% diabetes milieus, 71% had unstable angina. In the urgent-treatment group 40% had Hypercholesteremia and 59% had a trial hypertension. Whereas elective-treatment group in the urgent-treatment group 49% had Hypercholesteremia and 62% had a trial hypertension. Conclusion: Hypertension is a major risk factor in development of different cardiovascular events. Control of hypertension is crucial in reducing overall mortality and morbidity from ACS. In the study multiple drugs was manage to control blood pressure adequately.
A Perspective Review on Hyperledger Fabric Access Control System
Authors: Jebamalai Raj Stephen
Published: April 2023

Blockchain technology has enormous potential and is currently seen as a new technical trend with a quickening growth rate. Supply chain, health care, and finances are just a few of the application areas wherein blockchain-based systems are gaining interest. Whenever it comes to public and private management, data integrity is crucial and becoming more essential. Data integrity can be achieved in an access control system which is built on the blockchain. By using encryption protocols, access controls, and cryptography techniques, the Hyper ledger Fabric is created to be safe against unauthorised access and use. Systems for access control exist to safeguard resources against unwanted access. Platforms for blockchain systems, such as Hyperledger Fabric, are built with data integrity, complete transparency, and confidentiality. This article provides an in-depth analysis of a Hyperledger enterprise blockchain technology.
A Review on Artificial Intelligence Chip
Authors: Ebby Darney P.
Published: April 2023

As chipmakers design different types of chips to enable Artificial Intelligence (AI) applications, the adoption of AI chips has increased recently. To support applications based on deep learning, AI chips have inbuilt AI acceleration and are created with a specialized architecture. One of the key drivers boosting the market's expansion is the increasing integration of AI processors in data centers. The major significance of using AI chips when compared with traditional ICs are fast computational integration and large bandwidth. This study summarizes the need of the AI chips and its functionalities and how the AI chips varies from the general ICs. Finally, a discussion on the potential AI chip initiatives are provided.
Impact of Genetic Engineering on Agriculture Applications
Authors: Hariraman Kavitha
Published: April 2023

The primary goal of modern agriculture is to increase the amount and quality of crop production. Bacteria and other small organisms, plants, and animals can all be genetically modified. Genetic engineering helps the scientists to even transfer the targeted genes of one plant to another. This is also referred to as Genetically Modified Organisms (GMOs). Plants can be genetically modified to acquire particular traits. Even though this process differs from traditional breeding, it boosts the effectiveness in crop yield. The increased crop yields, lowered costs for food or drug production, reduced pesticide requirement, improved nutrient composition as well as food quality, increased pest and disease resistance, increased food security, and medical benefits are considered as the major objectives of genetic engineering in agriculture domain. This research study discusses about the genetically modified crops, their processes, advantages and the novel state-of-the-art cropping trends.
A Survey on Immune System in Genetic Engineering and their Applications
Authors: Alagirisamy Mukil
Published: April 2023

The increasing number of human diseases has become a major global concern. Researchers have found a novel way to defend against some of the deadliest diseases emerging across the globe. Incorporating a genetic modifications in immune cells can result in producing more powerful antibodies. With this technology, researchers have now successfully defended a potentially fatal lung infection. The similar approach might be effective in treating other human diseases. The integration of immune system in genetic engineering is being studied by combining wide range of techniques and organisms from agriculturally relevant plants to other genetic models such as Drosophila to humans. This initiates the research investigations on the rapid advancement of genetic engineering, including advancements in research and education. This study discusses the concept of genetic engineering in the immune system, as well as various types of genetic engineering and their applications. This work discusses about preserving an endangered species while promoting free market environmentalism.
Challenges and Opportunities for Online Learning in India
Authors: K Shanthini Jennefer
Published: April 2023

Today's digital world demands more effective learning models that allow students to actively participate/enrol in their education. Digital technology is influencing the way the instruction is delivered as well as the way the information is discovered and shared. Recently, the adoption of internet and mobile learning technologies have changed the traditional perspective of education. In India, e-learning could be the viable solution to provide education in the context of 21st century. Effective mobile and e-learning applications can be developed by conducting an analysis on the use of mobile devices and applications in online education. Despite numerous initiatives to promote the use of mobile learning for education, there are some issues that must be addressed. By considering the sudden shift towards online teaching in the rise of COVID-19 pandemic in India, this study summarizes the research findings of mobile and e-learning technologies to avoid potential complications with the implementation of this technology during any future pandemic situations in India. The proposed study also assists in understanding the current state of mobile learning technology adoption in India.
DIGITAL IMAGES CLASSIFICATION IN AUTOMATIC LAPAROSCOPIC DIAGNOSTICS
Authors: Bayzitov Dmytro M. , Liashenko Artem V. , Bayazitov Mykola R. , Bidnyuk Katerina A. , Godlevska Tamara L.
Published: April 2023

The aim: To evaluate the automatic computer diagnostic (ACD) systems, which were developed, based on two classifiers–HAAR features cascade and AdaBoost for the laparoscopic diagnostics of appendicitis and ovarian cysts in women with chronic pelvic pain.
Materials and methods: The training of HAAR features cascade, and AdaBoost classifiers were performed with images/ frames of laparoscopic diagnostics. Both gamma-corrected RGB and RGB converted into HSV frames were used for training. Descriptors were extracted from images with the method of Local Binary Pattern (LBP), which includes both data on color characteristics («modi!ed color LBP»-MCLBP) and textural features.
Results: Classification of test video images revealed that the highest recall for appendicitis diagnostics was achieved after training of AdaBoost with MCLBP descriptors extracted from RGB images – 0.708, and in the case of ovarian cysts diagnostics – for MCLBP gained from RGB images – 0.886 (P<0.05). Developed AdaBoost-based ACD system achieved a 73.6% correct classification rate (accuracy) for appendicitis and 85.4% for ovarian cysts. The accuracy of the HAAR features classifier was highest in the case of ovarian cysts identi!cation and achieved 0,653 (RGB) – 0,708 (HSV) values (P<0.05).
Conclusions: The HAAR feature-based cascade classifier turned out to be less e"ective when compared with the AdaBoost classifier trained with MCLBP descriptors. Ovarian cysts were better diagnosed when compared with appendicitis with the developed ACD
MORPHOMETRIC AND MORPHOLOGICAL ASSESSMENT OF CORONARY ARTERIES WITH INTRAVASCULAR ULTRASOUND
Authors: Pidvalna Uliana , Beshley Dmytro , Avramenko Iryna , Mateshuk-Vatseba Lesya
Published: April 2023

The aim: To perform a morphometric assessment of the coronary arteries ostia by intravascular ultrasound with morphological evaluation among the Ukrainian population.
Materials and methods: Intravascular images of the ostia of the right (48%) and left (52%) coronary arteries with the minimum diameter, maximum diameter, mean diameter and lumen area were analyzed. An intravascular ultrasound procedure was performed before percutaneous intervention.
Results: A total of 25 IVUS examinations were collected from patients of both sexes and the same ages: 61,27±10,24 for males and females 68±5,83 (p=0.64).The left coronary artery (LCA) ostium assessment was performed in 13 (52%) cases: 8 men and 5 women (32% and 20%, respectively). The right coronary artery (RCA) ostium assessment was performed in 12 (48%) cases: 7 men and 5 women (28% and 20%, respectively). The maximal diameter of the coronary artery ostia was higher in men (5.95±0.66mm) than in women (4.82±0.34mm) (p<0.0001). In men, the maximal diameter of the RCA was higher than in the LCA (6.4±0.40mm and 5.56±0.60mm, respectively). The same differences were found in the mean diameter and lumen area (p<0.05). In women, the minimum diameter, mean diameter, maximum diameter and lumen area of the RCA were higher than LCA but without statistically signi#cant di"erences. The anatomic precondition explains the observed changes in echogenicity.
Conclusions: IVUS analysis shows signi#cantly higher parameters of the minimum diameter, mean diameter, maximum diameter and lumen area in men than in women among the Ukrainian population. Therefore, morphological evaluation is crucial in the interpretation of intracoronary images.
GENETIC FEATURES OF CHILDREN WITH IDIOPATHIC SHORT STATURE
Authors: Ryznychuk Mariana , Bolshova Olena , Kvachenyuk Dmytro , Sprinchuk Natalya , Malinovska Tetiana
Published: April 2023

The aim: To investigate the clinical and genetic characteristics of children with idiopathic short stature, taking into account the polymorphism of the vitamin D receptor (VDR) BsmI gene.
Materials and methods: Eighteen children diagnosed with of idiopathic short stature who were treated at the State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism of the National Academy of Medical Sciences of Ukraine» were examined. The following values were taken into account: the patient’s sex and age, anthropometric data, vitamin D level in the blood (excluding summer months of patient recruitment), bone age, basal growth hormone (GH) level and its level after stimulation tests (clonidine, insulin), IGF-1 levels, blood levels of total and ionized calcium and VDR gene polymorphism.
Results: The A allele carriers of the polymorphic locus BsmI (rs1544410) of the VDR gene are signi!cantly associated with the risk of developing idiopathic short stature OR = 4.47 (95% CI 2.11-9.48; p <0.05). The risk of idiopathic short stature is significantly higher OR = 9.33 (95% CI 3.09-28.16; p <0.05) in children with the presence of the G/A genotype. Vitamin D deficiency (43.83 ± 6.47 nmol/l) was found in children with the BsmI polymorphic variant G/G VDR, and vitamin D insu"ciency was found in children with BsmI polymorphic variants G/A and A/A VDR (58.14 ± 20.05 and 51.58 ± 22.84 nmol/l, respectively).
Conclusions: The data obtained regarding the polymorphic locus BsmI (rs1544410) of the of VDR gene cannot exclude it’s the involvement in the pathogenesis of idiopathic short stature.
FUNCTIONAL STATE OF THE LIVER IN PULMONARY TUBERCULOSIS IN THE DYNAMICS OF PATHOGENETIC TREATMENT WITH A COMPLEX OF AMINO ACIDS
Authors: Shevchenko Olha S. , Todoriko Liliia D. , Pohorelova Olha O. , Semianiv Ihor O. , Ovcharenko Irina A. , Shevchenko Rostislav S. , Shevchenko Stanislav I. , Yeremenchuk Inga V. , Pidverbetska Olena V. , Toderika Yana I.
Published: April 2023

The aim: To investigate the in!uence of prescribing a complex of amino acids in pathogenetic therapy in patients with pulmonary tuberculosis on liver function.
Materials and methods: The study included 50 patients with drug susceptible TB and 50 patients with drug-resistant TB (multidrug-resistant and extensively drug-resistant).
Results: The study included 50 patients with drug susceptible tuberculosis (TB) and 50 patients with drug-resistant TB. When comparing biochemical pa-rameters characterizing liver function in patients with drug-susceptible TB after 1 month of anti-tuberculosis therapy, it was found that patients receiving additional therapy with a complex of amino acids had a lower level of bilirubin, p<0.05. After 60 doses, patients receiving additional therapy with amino acids had signi"cantly lower bilirubin levels alanine aminotransferase (ALT) and aspartate aminotransferase (AST), p <0.05. When comparing the biochemical parameters characterizing liver function in patients with drug-resistant tuberculosis after a month of anti-tuberculosis therapy, signi"cantly higher protein level was found in the groups of patients receiving additional therapy with amino acids, as well as signi"cantly lower ALT level, AST and creatinine p<0.05.
Conclusions: The additional appointment of the complex of amino acids in the pathogenetic therapy of patients with pulmonary tuberculosis makes it possible to reduce the severity of hepatotoxic reactions manifested by the main parameters (AST, ALT, total bilirubin) and to increase the protein-synthetic function of the liver, which allows us to recommend their appointment to improve the tolerance of anti-tuberculosis therapy.
PREDICTORS OF THE DEVELOPMENT OF EMOTIONAL BURNOUT AND THE MOTIVATIONAL COMPONENT OF THE MEDICAL STAFF OF HEALTH CARE INSTITUTIONS IN UKRAINE
Authors: Chorna Valentyna V. , Khliestova Svitlana S. , Gumeniuk Nataliia I. , Podolian Volodymyr M. , Shevchuk Tetiana I.
Published: April 2023

The aim: To study the stages and diseases of occupational and emotional burnout syndromes and characterize the changes in the psychophysiological state of the medical staff of health care institutions.
Materials and methods: Manifestations and levels of predictors of the development of emotional burnout (PDEB), motivation of medical workers in the Vinnytsia region, and preventive measures of PDEB to improve the motivational component of medical workers. Statistical processing of the research results was performed in the licensed standardized package “Statistica 6.1 for Windows”, and included the analysis of the nature of the distribution of characteristics using the Shapiro-Wilk’s W test, and the analysis of di"erences using the Mann-Whitney test. The content analysis of domestic and foreign scienti#c sources and biblio-semantic and analytical research methods were used in the work. A sociological study was conducted on the dynamics of changes in the psycho-physiological state of health of medical staff of psychiatric hospitals and medical sta" of general health care facilities (CHP) in the Vinnytsia region, depending on gender and positions.
Results: A survey has been conducted using psychodiagnostic methods of emotional burnout by Boyko V.V. and the adapted approach of Vodopyanova N.E. According to the results of K. Zamfir’s method in A. Rean’s modification, it was established that external negative motivation exceeds external positive motivation in health care staff, as in male doctors and female doctors from 3,2±0,8 to 2,7±1,0 score and the average medical staff of psychiatric profile in men 3,2±1,8 and 3,0±1,3 and the average medical staff of general pro#le 3,6±1,0 and 3,2±1,1, respectively, which re$ects the negative attitude of the medical sta" at the present stage to the implementation of professional activities.
Conclusions: Predictors of the development of emotional burnout are noted in the average female medical workers working in psychiatric institutions: “Stress” - 41.3±19.2 points versus 33.6±22.2 points (p>0.05), “Resistance » – 56.6±21.4 points against 40.5±16.6 points (p<0.05), “Exhaustion” – 41.5±21.4 points against 39.4±27.4 points (p >0.05) compared to men, who may be at risk of transition from a pre-morbid state (mild, moderate form of SPV) to a severe form of chronic psychosomatic or psychovegetative disorder.
"Idź córko do morza nieznanego, nie bierz nic ze sobą prócz wędki i cienkiej dwojnicy". Symboliczno-obrzędowa interpretacja baśni "Rybak Palunko i jego żona" Ivany Brlić-Mažuranić
Authors: Rusek Iwona E.
Published: April 2023

The text analyzes the symbolic and ritual meaning of a fairy tale by the Croatian writer Ivana Brlić-Mazuranic entitled Palunko the fisherman and his wife. The title character wants to find a way to the seat of the Sea King to live there in carefree and wealthy. Neither the loss of his son nor his wife’s illness can stop him from achieving this goal. However, she is the one who, by performing a series of rituals, especially her own internal transformation, finds her husband and son, which leads to the recovery of the lost community. In the text, Brlić-Mazuranic uses symbolism related to the daily cycle (dawn, midnight), elements (water, fire, air), divine beings (Aurora), and above all Slavic beliefs, the remnants of which have been preserved only in fairy tales, especially about the island of Bujan, the Alatyr stone or the twigs.
"Czy Juno we własnej osobie, czy inne jakoweś bóstwo", czyli o ukraińskich bohaterkach dzieł Henryka Sienkiewicza
Authors: Szargot Barbara
Published: April 2023

The author presents the fate of Ukrainian heroines in Henryk Sienkiewicz’s works. She reflects, among other things, on the awareness of the Ukrainianness of these characters. According to the researcher, the three Helens described so elaborately by Sienkiewicz (who did not know Ukraine and Ukrainian women) are the embodiment of the ideas that the writer-reader of works from the “Ukrainian school” had. According to them, Ukrainian women are so beautiful that they seem to belong to a myth, so spontaneous that they are ready to go against custom, and so loving that it is impossible not to love each other.
Дискурси влади у творчості юліуша словацького
Authors: Kornilyeva Liliya
Published: April 2023

Juliusz Słowacki, a Polish Romantic poet and dramatist, was born in Krzemieniec,where he spent part of his life. As a result, he was well-versed in Ukrainian, and asa writer, he largely depended on Ukrainian settings, Ukrainian history, and Ukrainian folklore. Ukrainian themes became an inherent part of his literary works. Bestknown for his masterpieces Balladyna (1834), Mazepa (1839), Lilla Weneda (1840),Jan Kazimierz (1839), Bienowski (1841), Sen srebrny Salomei (1843), and Ksiądz Marek(1843), Słowacki is now regarded as an outstanding writer, whose ideas and aestheticvalues influenced generations of other European artists. Underrated during his lifetime, he appears at his most resplendent nowadays. The discourses of power in theworks of Słowacki are given close attention because they are of crucial importance forhis original texts. The multi-faceted personalities of numerous monarchs depicted byhim, give an insight into the author’s understanding of power and its nature.
Джерела Шевченкової обізнаності із творчістю Тимка Падури (з нових коментарів до повістей)
Authors: Boron Oleksandr
Published: April 2023

The paper assumes that Shevchenko became acquainted with Tymko Padura’s poetry primarily through oral tradition, not through publications. Accordingly, it questions the statement from the commentary to the novel A Walk with Pleasureand Not Without a Moral in the latest Complete Works of Shevchenko, which says that he quoted one of Padura’s songs from the 1842 Lviv edition. The prototype of Padura’s collection described in the novel was probably the Warsaw edition of 1844. It is also suggested that in future academic publications, it should be noted that Yan Komarnytskyi was not the author of the song “I returned from Siberia,” one of the versions of which is put in Shevchenko’s diary. The Ukrainian poet wrongly attributed it to Padura.
Тарас Шевченко і Тадеуш Лада Заблоцький: типологічні збіги у біографії і творчості поетів-романтиків у Російській імперії пер. пол. ХІХ ст.
Authors: Kharchuk Roxana
Published: April 2023

According to the author, Tsar Nicholas I’s punishment of Taras Shevchenko and Tadeusz Łada-Zabłocki for their poems with exile to Orenburg and the Caucasus in the rank of privates, respectively, is evidence of the Russian Tsar’s phobia of literature and freedom of thought. The article concludes that in the context of possible familiarity between the fates of the two authors, the typological similarities in their works are not significant. The main concern is the influence of Ukrainian folklore on the imagery in Shevchenko’s poetry, and Ukrainian and Belarusian folklore on the imagery in Łada-Zabłocki’s. Although both poets are Romantics, their poetic self-creation is diametrically opposed. In Łada-Zabłocki’s it is autobiographical imagery, marked by the experience of the defeat of the Polish nation in the struggle for freedom after the November Uprising, while in Shevchenko’s the poet always appears as a defender of the most wronged part of the nation. While the element of Shevchenko’s poetry is not only lyricism but his poetry is characterized by epic breath, Łada-Zabłocki belongs to the group of autobiographical poets.