bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between Traumatic Subarachnoid Hemorrhage and Acute Respiratory Failure in Moderate-to-Severe Traumatic Brain Injury Patients
Authors: Li Min , Wang Rui , Fang Qi-Xing , He Yi-Xuan , Shi Ying-Wu , Ge Shun-Nan , Ma Rui-Na , Qu Yan
Published: July 2022

Acute respiratory failure (ARF) with a high incidence among moderate-to-severe traumatic brain injury (M-STBI) patients plays a pivotal role in worsening neurological outcomes. Traumatic subarachnoid hemorrhage (tSAH) is highly prevalent in M-STBI, which is associated with significant adverse outcomes. In this retrospective cohort study, we aimed to explore the association between the severity of the tSAH and ARF in the M-STBI population. A total of 771 subjects were reviewed. Clinical and neuroimaging data of M-STBI patients were retrospectively collected, and ARF was ascertained retrospectively based on their electronic medical record. The degree of tSAH was classified according to Fisher’s criteria, and the grade of tSAH was dichotomized to a low Fisher grade (Fisher grade 1–2) and a high Fisher grade (Fisher grade 3–4). After exclusion procedures, the data of 695 M-STBI patients were analyzed. A total of 284 (30.8%) had a high Fisher grade on admission. The overall rate of ARF within 48 h upon admission was 34.4% (239/695); it was 29.5% (142/481) and 46.3% (99/214) for the low and high Fisher groups, respectively. In a full cohort, a high Fisher grade was associated with ARF after adjusting for age, gender, GCS, smoking history, comorbidities, multiple injuries, characteristics of TBI, and pulmonary factors (OR 1.78; 95% CI, 1.11–2.85, p = 0.016). This result remained robust in the comparisons after PSM (71/132, 42.8% vs. 53/132, 31.9%; OR, 1.59; 95% CI, 1.02–2.49, p = 0.042). A high Fisher SAH grade exposure on admission is associated with ARF in M-STBI patients.
Flange Wrinkling in Deep-Drawing: Experiments, Simulations and a Reduced-Order Model
Authors: Chen Kelin , Carter Adrian J. , Korkolis Yannis P.
Published: July 2022

Flange wrinkling is often seen in deep-drawing process when the applied blankholding force is too small. This paper investigates the plastic wrinkling of flange under a constant blankholding force. A series of deep-drawing experiments of AA1100-O blanks are conducted with different blankholding forces. The critical cup height and wrinkling wave numbers for each case is established. A reduced-order model of flange wrinkling is developed using the energy method, which is implemented to predict the flange wrinkling of AA1100-O sheet by incrementally updating the flange geometry and material hardening parameters during the drawing process. A deep-drawing finite element model is developed in ABAQUS/standard to simulate the flange wrinkling of AA1100-O blanks under constant blankholding force. The predicted cup height and wave numbers from the finite element model and reduced-order model are compared with the experimental results, which demonstrates the accuracy of the reduced-order model, and its potential application in fast prediction of wrinkling in deep-drawing process.
A Bayesian Approach to Carrying Capacity Estimate: The Case of Greek Coastal Cage Aquaculture
Authors: Conides Alexis , Zoulias Theodoros , Pavlidou Alexandra , Zachioti Panagiota , Androni Afroditi , Kabouri Georgia , Rouselaki Eleni , Konstantinopoulou Aggeliki , Pagou Kaliopi , Klaoudatos Dimitris
Published: July 2022

The estimation of the carrying capacity (CC) is a fundamental process in integrated environmental management, policy making, and decision making. Aquaculture carrying capacity has been studied since the 1960s to allow estimation of the production limits of aquaculture projects and, hence, their maximum economic performance within sustainable limits for the local environment. One major drawback of these approaches is that they can provide CC estimates after a fish farm is installed and operates in a certain location (ex post approaches). This paper approaches the estimation of CC using a Bayesian/CHAID model of profiling information on the environmental quality, geomorphology, and human activities on the adjacent coastal area (land side) using as an indicator the trophic state of the marine area in terms of chlorophyll-a concentration (upper mesotrophic). This way, having the above information for a certain site, it is possible to calculate the maximum annual production of a cage fish farm so that the trophic state of the area will not exceed the environmental goal of the upper mesotrophic level. We examined the effects of 27 different physical, chemical, social and geomorphological parameters on CC (in fish biomass terms). CC was found to be correlated by particulate nitrogen (PN), silicates (Si-SiO4), salinity, and suspended particulate matter (SPM). The overall relationship found is: Biomassat CC level = +473.762[Chl-a] − 6856.64[PN] + 9.302[Salinity] − 473.5[Si-SiO4] + 341.864[SPM] − 207.046. The analysis performed allowed us to estimate the maximum levels for each factor to maintain a eutrophication status up to the upper mesotrophic level: particulate nitrogen < 0.018 mg/L, silicates < 0.137 mg/L, salinity > 38 PSU and SPM > 0.815 mg/L. Finally, the current fish farm licensing legislation in Greece concerning the CC estimation algorithm is discussed.
Systematic Identification of Essential Genes Required for Yeast Cell Wall Integrity: Involvement of the RSC Remodelling Complex
Authors: Sanz Ana Belén , Díez-Muñiz Sonia , Moya Jennifer , Petryk Yuliya , Nombela César , Rodríguez-Peña José M. , Arroyo Javier
Published: July 2022

Conditions altering the yeast cell wall lead to the activation of an adaptive transcriptional response mainly governed by the cell wall integrity (CWI) mitogen-activated protein kinase (MAPK) pathway. Two high-throughput screenings were developed using the yTHC collection of yeast conditional mutant strains to systematically identify essential genes related to cell wall integrity, and those required for the transcriptional program elicited by cell wall stress. Depleted expression of 52 essential genes resulted in hypersensitivity to the dye Calcofluor white, with chromatin organization, Golgi vesicle transport, rRNA processing, and protein glycosylation processes, as the most highly representative functional groups. Via a flow cytometry-based quantitative assay using a CWI reporter plasmid, 97 strains exhibiting reduced gene-reporter expression levels upon stress were uncovered, highlighting genes associated with RNA metabolism, transcription/translation, protein degradation, and chromatin organization. This screening also led to the discovery of 41 strains displaying a basal increase in CWI-associated gene expression, including mainly putative cell wall-related genes. Interestingly, several members of the RSC chromatin remodelling complex were uncovered in both screenings. Notably, Rsc9 was necessary to regulate the gene expression of CWI-related genes both under stress and non-stress conditions, suggesting distinct requirements of the RSC complex for remodelling particular genes.
Morpho-Phylogenetic Evidence Reveals Novel Pleosporalean Taxa from Sichuan Province, China
Authors: Yu Xian-Dong , Zhang Sheng-Nan , Liu Jian-Kui
Published: July 2022

Pleosporales is the largest and most morphologically diverse order in Dothideomycetes, including a large proportion of saprobic fungi. During the investigation of microfungi from decaying wood in Sichuan Province, several novel fungal taxa of asexual and sexual morphs were collected, identified, and well-described. Phylogenetic analyses based on SSU, ITS, LSU, RPB2 and TEF1α gene sequences suggested that these new taxa were related to Pleosporales and distributed in five families, viz. Amorosiaceae, Bambusicolaceae, Lophiostomataceae, Occultibambusaceae and Tetraplosphaeriaceae. The morphological comparison and molecular phylogeny evidence justify the establishment of six new taxa, namely Bambusicola guttulata sp. nov., Flabellascoma sichuanense sp. nov., Neoangustimassarina sichuanensis gen. et sp. nov., Occultibambusa sichuanensis sp. nov. and Pseudotetraploa bambusicola sp. nov. Among them, Neoangustimassarina was introduced as the second sexual morph genus in Amorosiaceae; Bambusicola guttulata, O. sichuanensis and P. bambusicola were isolated from bamboos, which contributed to the diversity of bambusicolous fungi. The detailed, illustrated descriptions and notes for each new taxon are provided, as well as a brief note for each family. The potential richness of fungal diversity in Sichuan Province is also discussed.
Vascular Calcification Is Associated with Fetuin-A and Cortical Bone Porosity in Stone Formers
Authors: Rodrigues Fernanda Guedes , Neves Rodrigo Fernandes Carvalho Azambuja , Ormanji Milene Subtil , Esper Priscila Ligeiro Gonçalves , Gaspar Melissa , Pereira Rosa Maria Rodrigues , Requião-Moura Lucio R. , de Borst Martin H. , Heilberg Ita Pfeferman
Published: July 2022

Background: Nephrolithiasis has been associated with bone loss and vascular calcification (VC), reflecting abnormal extraosseous calcium deposition. Fetuin-A (Fet-A) acts as a potent inhibitor of ectopic mineralization. The aim of the present study was to evaluate the prevalence of VC in stone formers (SF) and non-stone formers (NSF) and to investigate potential determinants of VC among SF, including circulating levels of Fet-A and bone microarchitecture parameters. Methods: Abdominal aortic calcification (AAC) was assessed using available computed tomography in SF and in age-, sex-, and BMI-matched NSF (potential living kidney donors). Serum Fet-A was measured in stored blood samples from SF. Bone microarchitecture parameters were obtained as a post hoc analysis of a cross-sectional cohort from young SF evaluated by high-resolution peripheral quantitative computed tomography (HR-pQCT). Results: A total of 62 SF (38.0 [28.0–45.3] years old) and 80 NSF (40.0 [37.0–45.8] years old) were included. There was no significant difference in AAC scores between SF and NSF. However, when dividing SF according to mean AAC score, below <5.8% (n = 33) or above ≥5.8% (n = 29), SF with higher AAC presented significantly higher BMI and tibial cortical porosity (Ct.Po) and significantly lower serum HDL, klotho, Fet-A, and eGFR. Urinary calcium did not differ between groups, but fractional excretion of phosphate was higher in the former. Upon multivariate regression, BMI, serum Fet-A, and tibial Ct.Po remained independently associated with AAC. Conclusions: This study suggests an association between reduced circulating Fet-A levels and increased bone Ct.Po with VC in SF.
Identification and Functional Analysis of SabHLHs in Santalum album L.
Authors: Zhang Ting , Chen Xiaohong , Xiong Yuping , Niu Meiyun , Zhang Yueya , Yan Haifeng , Li Yuan , Zhang Xinhua , Ma Guohua
Published: July 2022

Santalum album L., a semi-parasitic evergreen tree, contains economically important essential oil, rich in sesquiterpenoids, such as (Z) α- and (Z) β-santalol. However, their transcriptional regulations are not clear. Several studies of other plants have shown that basic-helix-loop-helix (bHLH) transcription factors (TFs) were involved in participating in the biosynthesis of sesquiterpene synthase genes. Herein, bHLH TF genes with similar expression patterns and high expression levels were screened by co-expression analysis, and their full-length ORFs were obtained. These bHLH TFs were named SaMYC1, SaMYC3, SaMYC4, SaMYC5, SabHLH1, SabHLH2, SabHLH3, and SabHLH4. All eight TFs had highly conserved bHLH domains and SaMYC1, SaMYC3, SaMYC4, and SaMYC5, also had highly conserved MYC domains. It was indicated that the eight genes belonged to six subfamilies of the bHLH TF family. Among them, SaMYC1 was found in both the nucleus and the cytoplasm, while SaMYC4 was only localized in the cytoplasm and the remaining six TFs were localized in nucleus. In a yeast one-hybrid experiment, we constructed decoy vectors pAbAi-SSy1G-box, pAbAi-CYP2G-box, pAbAi-CYP3G-box, and pAbAi-CYP4G-box, which had been transformed into yeast. We also constructed pGADT7-SaMYC1 and pGADT7-SabHLH1 capture vectors and transformed them into bait strains. Our results showed that SaMYC1 could bind to the G-box of SaSSy, and the SaCYP736A167 promoter, which SaSSy proved has acted as a key enzyme in the synthesis of santalol sesquiterpenes and SaCYP450 catalyzed the ligation of santalol sesquiterpenes into terpene. We have also constructed pGreenII 62-SK-SaMYC1, pGreenII 0800-LUC-SaSSy and pGreenII 0800-LUC-SaCYP736A167 via dual-luciferase fusion expression vectors and transformed them into Nicotiana benthamiana using an Agrobacterium-mediated method. The results showed that SaMYC1 was successfully combined with SaSSy or SaCYP736A167 promoter and the LUC/REN value was 1.85- or 1.55-fold higher, respectively, than that of the control group. Therefore, we inferred that SaMYC1 could activate both SaSSy and SaCYP736A167 promoters.
The Entomopathogenic Nematodes H. bacteriophora and S. carpocapsae Inhibit the Activation of proPO System of the Nipa Palm Hispid Octodonta nipae (Coleoptera: Chrysomelidae)
Authors: Sanda Nafiu , Hou Bofeng , Hou Youming
Published: July 2022

Entomopathogenic nematodes are biocontrol agents of invasive insect pests in soil and cryptic habitats. Nipa palm hispid, Octodonta nipae, is a pest of palm trees in Sothern China. To address its increasing damage, environmentally friendly control methods are required. This study aimed to test efficacy of Heterorhabditis bacteriophora and Steinernema carpocapsae on O. nipae and investigated the influence of secondary metabolites, nematodes, and their isolated cuticles on the activation of O. nipae’s prophenoloxidase system using qPCR analysis. Our data revealed that O. nipae were less susceptible to H. bacteriophora than S. carpocapsae and penetrations of infective juveniles were higher with S. carpocapsae treatment than H. bacteriophora. Moreover, expression levels of the serine protease P56, prophenoloxidase activation factor 1, PPO and serine protease inhibitor 28 upon S. carpocapsae and H. bacteriophora infections were generally downregulated at all times. However, upon heating, the cuticles lost their inhibitory effects and resulted in upregulation of the PPO gene. Similarly, the addition of arachidonic acid reversed the process and resulted in the upregulation of the PPO gene compared to the control. Further work is needed to identify toxic substances secreted by these EPNs to evade O. nipae’s immune system.
Correlation between Angiotensin Serum Levels and Very-Low-Frequency Spectral Power of Heart Rate Variability during Hemodialysis
Authors: del Valle-Mondragón Leonardo , Becerra-Luna Brayans , Cartas-Rosado Raúl , Infante Oscar , Pérez-Grovas Héctor , Lima-Zapata Larissa I. , Lerma Claudia , Rodríguez-Chagolla José , Martínez-Memije Raúl
Published: July 2022

Cardiovascular regulatory mechanisms that fail to compensate for ultrafiltration and cause hypovolemia during hemodialysis (HD) are not completely understood. This includes the interaction between the autonomic nervous system and the biochemistry that regulates blood pressure and modulates cardiac activity and vascular tone in response to hypovolemia in patients treated with HD. The objective was to evaluate the association of spectral indices of heart rate variability (HRV) with serum levels of angiotensin II, angiotensin 1–7, nitric oxide and total antioxidant capacity during HD. Electrocardiographic records were obtained from 20 patients during HD (3 h), from which HRV data and spectral power data in the very-low-frequency (VLF), low-frequency (LF) and high-frequency (HF) bands were generated. Three blood samples per patient were collected during HD (0.0, 1.5, 3.0 h) to determine the levels of biomarkers involved in the pressor response during HD. Angiotensin II had a positive correlation with VLF (r = 0.390) and with LF/HF (r = 0.359) and a negative correlation with LF (r = −0.262) and HF (r = −0.383). There were no significant correlations between HRV and the other biomarkers. These results suggest that during HD, VLF could reflect the serum levels of angiotensin II, which may be associated with the autonomic response to HD.
Phylogeographical Analysis of the Freshwater Gudgeon Huigobio chenhsienensis (Cypriniformes: Gobionidae) in Southern China
Authors: Yang Xishu , Ni Xiaomin , Fu Cuizhang
Published: July 2022

The freshwater gudgeon Huigobio chenhsienensis (Cypriniformes: Gobionidae) is a small fish endemic to southern China. In this study, we used mitochondrial cytochrome b gene (Cytb), from wide-ranging samplings of H. chenhsienensis from the Ou River (the central of southern China) to the Yangtze River Basin (the northernmost part of southern China) to explore genetic variations and the evolutionary history of H. chenhsienensis in southern China. In total, 66 haplotypes were identified from Cytb sequences of 142 H. chenhsienensis individuals, which could be divided into lineages A, B, and C with divergence times of ~4.24 Ma and ~3.03 Ma. Lineage A was distributed in the lower reaches of the Yangtze River, the Oujiang River, and the Jiao River, lineage B was distributed in the Qiantang River and the Cao’e River, whereas lineage C was restricted to the Poyang Lake drainage from the middle reaches of the Yangtze River. Lineage A could be subdivided into sub-lineages A-I, A-II, A-III, and A-IV, with divergence times of 1.30, 0.97, and 0.44 Ma. Lineage C could be subdivided into sub-lineages C-I and C-II, with a divergence time of 0.85 Ma. Our findings indicate that climate change during the Pliocene and Pleistocene eras, as well as the limited dispersal ability of H. chenhsienensis, have been major drivers for shaping the phylogeographical patterns of H. chenhsienensis.
Caffeine Decreases Hepcidin Expression to Alleviate Aberrant Iron Metabolism under Inflammation by Regulating the IL-6/STAT3 Pathway
Authors: Li Zhong-Da , Geng Meng-Yu , Dou Song-Rui , Wang Xuan , Zhang Zi-Han , Chang Yan-Zhong
Published: July 2022

Caffeine is well-known as a psychostimulant, and it can also be beneficial in numerous diseases such as diabetes and different types of cancer. Previous studies have shown that caffeine can have a protective role in bacterial infection-induced inflammation and hyperoxia-mediated pulmonary inflammation. Hepcidin, which is regulated by the IL-6/STAT3 inflammation pathway, is a peptide hormone that maintains systemic iron homeostasis. We hypothesized that caffeine’s effects on inflammation may also influence hepcidin production and therefore systemic iron metabolism. To this end, we treated 2-month-old mice with caffeine by daily intragastric administration for 7 days, administering intraperitoneal LPS after the final caffeine treatment. Twelve hours after LPS treatment the mice were euthanized, and tissues were collected. We found that caffeine decreased hepatic hepcidin expression and attenuated LPS-induced hepatic hepcidin overexpression. IL-6 expression and STAT3 phosphorylation were also reduced upon caffeine administration. Additionally, hepatic and splenic FPN1 levels increased after caffeine treatment, leading to lower iron levels in liver and spleen tissues and higher iron levels in serum. Caffeine also prevented the increase in spleen weight and decrease in body weight after LPS treatment. Together, our findings suggest that caffeine decreases hepcidin expression via inhibiting inflammation and the activation of the IL-6/STAT3 pathway, thus presenting an attractive, potential therapeutic for the treatment of anemia of inflammation.
Antioxidant and Anti-Urolithiatic Activity of Aqueous and Ethanolic Extracts from Saussurea costus (Falc) Lispich Using Scanning Electron Microscopy
Authors: Mammate Naima , El oumari Fatima Ezzahra , Imtara Hamada , Belchkar Salim , Lahrichi Anissa , Alqahtani Ali S. , Noman Omar M. , Tarayrah Mahmoud , Houssaini Tarik Sqalli
Published: July 2022

The plant Saussurea costus (Falc) Lipsch has many biological activities and a strong curative and preventive power against a variety of diseases including cancer, diabetes, and hemorrhoids. In the current study, phytochemical screening was carried out as well as an investigation of the antilithiatic and antioxidant activities of aqueous and ethanolic extracts of this plant. The results showed that aqueous and ethanolic extracts were effective in reducing cystine stone mass and that the aqueous extract of Saussurea costus (Falc) Lipsch had the highest percentage of dissolution (6.756 ± 1.024) (p < 0.05). A turbidimetric method and a crystallization test were used to evaluate the antilithiatic activity of an aqueous and ethanolic extract of this plant on calcium oxalate crystallization. The results of these methods revealed that the ethanolic extract of this plant has a significant inhibitory effect on calcium oxalate crystallization, with a percentage inhibition of (91.017 ± 0.299) (p < 0.05) for a concentration of 2 mg mL−1. The DPPH method revealed that the ethanolic extract of Saussurea costus (Falc) Lipsch with a concentration of (IC50 = 0.12325 mg mL−1) had the highest IC50, whereas the FRAP method revealed that the aqueous extract of Saussurea costus (Falc) Lipsch with a concentration of 300 µg mL−1 has the most significant reducing power with (OD = 0.56 ± 0.05). These findings indicate that aqueous and ethanolic extracts of Saussurea costus (Falc) Lipsch had a significant effect on whewellite and weddellite and a greater free radical scavenging effect but had no effect on cystine dissolution.
Influence of Adsorption Characteristics of Surfactants Sodium Dodecyl Sulfate and Aerosol–OT on Dynamic Process of Water-Based Lubrication
Authors: Fang Jingbo , Bai Pengpeng , Ouyang Chuke , Liu Chenxu , Wen Xiangli , Li Yuanzhe , Meng Yonggang , Ma Liran , Tian Yu
Published: July 2022

Surfactant solutions are widely used in industry, and their steady-state lubrication properties have been comprehensively explored, while the “dynamic process” between steady states attracts much less attention. In this study, the lubrication behaviors of sodium dodecyl sulfate (SDS) and sodium bis (2–ethylhexyl) sulfosuccinate (Aerosol–OT, AOT) solutions were comparatively and extensively discussed. Experimental results showed that the duration of the dynamic process of AOT solution lubrication was significantly shorter than that of SDS. The essence of the dynamic process was revealed from the aspects of the running-in of solid surfaces and the adsorption process of surfactant molecules. Unlike the general recognition that the friction force evolution mainly corresponds to the running-in of surfaces, this study indicated that the dynamic adsorption behavior of surfactant molecules mainly contributes to this process. Various experiments and analyses showed that the smaller steric hindrance and lower orientation speed of SDS molecules led to longer diffusion into the confined contact zone and a longer duration of friction force decrease. This work enhances our understanding of the dynamic friction process in water-based lubrication, which could also have important implications for oil-based lubrication and its industrial applications.
Assessment of the Impacts of Green Synthesized Silver Nanoparticles on Maerua oblongifolia Shoots under In Vitro Salt Stress
Authors: Shaikhaldein Hassan O. , Al-Qurainy Fahad , Nadeem Mohammad , Khan Salim , Tarroum Mohamed , Salih Abdalrhaman M. , Alansi Saleh , Al-Hashimi Abdulrahman , Alfagham Alanoud , Alkahtani Jawaher
Published: July 2022

Salinity is one of the major abiotic stresses that affect the plant’s growth and development. Recently, the contribution of nanoparticles (NPs) to ameliorating salinity stresses has become the new field of interest for scientists due to their special physiochemical properties in the biological system. This study is designed to examine the effects of biosynthesized silver nanoparticles (AgNPs) spherical in shape (size range between 9 and 30 nm) on morphophysiological characteristics and the antioxidant defense system of in vitro raised Maerua oblongifolia under four levels of salt stress (0, 50, 100, and 200 mM NaCl). Our findings reveal that the application of AgNPs (0, 10, 20, and 30 mg/L) to M. oblongifolia shoots significantly alleviates the adverse effects of salt stress and ameliorates plant developmental-related parameters and defense systems. High salinity elevates the oxidative damage by over-accumulation of the levels of total soluble sugars, proline, hydrogen peroxide (H2O2), and malondialdehyde (MDA). In addition, enhancing the activity of the antioxidant enzymes, total phenolic, and flavonoid content over the control. Interestingly, the application of AgNPs to salinized plants improved the growth traits and photosynthetic pigment production and caused higher enhancement in antioxidant enzyme activities. Furthermore, mitigating the oxidative damage by lowering the accumulation of proline, soluble sugars, H2O2, MDA, and total phenolic and flavonoid contents in salt-stressed plants. In general, AgNPs augmented the growth of M. oblongifolia shoots under saline conditions through different strategies; thus, AgNPs can be used as an appropriate eco-friendly approach that enhances salinity tolerance in plants.
Sustainable Management of Calcite Contaminated with Waste Toner Powder in the Construction Industry
Authors: Kominko Halyna , Radomski Piotr , Nowak Anna K. , Wzorek Zbigniew
Published: July 2022

Due to the highly explosive nature of toners, absorbers are used in toner processing plants to prevent the explosion of toner dust suspension in the air. Usually, finely divided calcite (in the form of a dust) is used. The mixture of toner-calcite is treated as waste and landfilled. The main aim of this study was to investigate the possibility of using toner-contaminated calcite as an additive to concrete. Materials originating from the toner processing plant were analyzed by using TGA, AAS, XRD, FTIR and SEM techniques. Calcite-waste toner powder mixture in amounts 0%, 1%, 5%, 10%, 15% and 20% were used to produce concrete. The results of the study showed that an increase in the amount of calcite contaminated with toner to 20% causes a decrease in compressive strength of concrete by 24–51% depending on material sample. The addition of calcite in amounts up to 5% can be a suitable method of its management.
Ferrimagnetic Clusters as the Origin of Anomalous Curie–Weiss Behavior in ZnFe2O4 Antiferromagnetic Susceptibility
Authors: Hernando Antonio , Cobos Miguel Ángel , Jiménez José Antonio , Llorente Irene , García-Escorial Asunción , de la Presa Patricia
Published: July 2022

Different studies carried out in the last three decades on the magnetic susceptibility of the spinel ZnFe2O4 ferrite have revealed the positive character of its Curie–Weiss temperature, contradicting its observed antiferromagnetic behavior which is characterized by a well-defined susceptibility peak centered around the Neel temperature (10 K). Some approaches based on ab initio calculations and mixture of interactions have been attempted to explain this anomaly. This work shows how for very low values of the inversion parameter, the small percentage of Fe atoms located in tetrahedral sites gives rise to the appearance of ferrimagnetic clusters around them. Superparamagnetism of these clusters is the main cause of the anomalous Curie–Weiss behavior. This finding is supported experimentally from the thermal dependence of the inverse susceptibility and its evolution with the degree of inversion.
Reactive Printing and Wash Fastness of Inherent Flame Retardant Fabrics for Dual Use
Authors: Glogar Martinia , Pušić Tanja , Lovreškov Veronika , Kaurin Tea
Published: July 2022

The possibility of reactive printability on protective flame—resistant fabrics, varied in composition of weft threads and weave was investigated. In addition, the wash fastness of printed samples was analyzed. The functional properties of fabrics were assessed by measuring of the Limiting Oxygen Index (LOI). Printing was performed with two printing pastes varied in thickeners and two dyestuff concentrations. The samples were analyzed by microscopic imaging using digital microscope and spectrophotometric measurement before and after the five washing cycles. The results confirmed the printability of FR inherent fabrics specified through fine colored effects and optimal wash fastness.
Corrosion Resistance of 3D Printed Ti6Al4V Gyroid Lattices with Varying Porosity
Authors: Sharp Rachael , Pelletier Matthew H. , Walsh William R. , Kelly Cambre N. , Gall Ken
Published: July 2022

Corrosion of medical implants is a possible failure mode via induced local inflammatory effects, systemic deposition and corrosion related mechanical failure. Cyclic potentiodynamic polarisation (CPP) testing was utilized to evaluate the effect of increased porosity (60% and 80%) and decreased wall thickness in gyroid lattice structures on the electrochemical behaviour of LPBF Ti6Al4V structures. The use of CPP allowed for the landmarks of breakdown potential, resting potential and vertex potential to be analysed, as well as facilitating the construction of Tafel plots and qualitative Goldberg analysis. The results indicated that 60% gyroid samples were most susceptible to the onset of pitting corrosion when compared to 80% gyroid and solid samples. This was shown through decreased breakdown and vertex potentials and were found to correlate to increased lattice surface area to void volume ratio. Tafel plots indicated that despite the earlier onset of pitting corrosion, both gyroid test groups displayed lower rates of corrosion per year, indicating a lower severity of corrosion. This study highlighted inherent tradeoffs between lattice optimisation and corrosion behaviour with a potential parabolic link between void volume, surface area and corrosion being identified. This potential link is supported by 60% gyroid samples having the lowest breakdown potentials, but investigation into other porosity ranges is suggested to support the hypothesis. All 3D printed materials studied here showed breakdown potentials higher than ASTM F2129′s suggestion of 800 mV for evaluation within the physiological environment, indicating that under static conditions pitting and crevice corrosion should not initiate within the body.
Investigation of Waste Electrical Power Plant Oil as a Rejuvenating Agent for Reclaimed Asphalt Binders and Mixtures
Authors: El-labbad Eman M. , Heneash Usama , El-Badawy Sherif M.
Published: July 2022

One of the main difficulties with employing recycled asphalt pavement (RAP) in hot mix asphalt (HMA) is bitumen aging; hence, the percentage of RAP in the HMA is limited. This research evaluates the rheological properties of the RAP binder and the performance of HMA containing high RAP content using waste engine oil (WEO) from an Electrical Power Plant as a rejuvenator. The rheological and microstructural properties of the RAP binder and rejuvenated RAP binder were determined in the laboratory. Both the recycled and rejuvenated recycled mixes were tested for Marshall stability, indirect tensile strength, dynamic modulus (E*), and flow number tests. The RAP binder was recovered using two different processes: rotavapor distillation followed by centrifugation (RCRD) and column distillation without centrifugation (RNCCD). The optimal WEO percentages for the RCRD and RNCCD recovery procedures were 0.5% and 3%, respectively. The Marshall test results revealed that adding WEO to the recycled mix enhanced its stability and flow compared to the control mix. The rejuvenated mix containing recovered binder from the RCRD recovery process was found to be better than the rejuvenated mix containing recovered binder from the RNCCD recovery process. The rejuvenated recycled mixes outperformed the recycled mix in terms of moisture resistance, which was evidenced by tensile strength ratio values of 0.88, 0.90, and 0.91 for the control and 0.5% and 3% WEO modified mixes, respectively. Finally, the results of dynamic modulus and flow number testing revealed that the rejuvenated mixes had a modest drop in both the dynamic modulus and flow number compared to the non-rejuvenated mix.
Functionalization of Se-Te Nanorods with Au Nanoparticles for Enhanced Anti-Bacterial and Anti-Cancer Activities
Authors: Khan Shahin Shah , Ullah Irfan , Zada Shah , Ahmad Aftab , Ahmad Waqar , Xu Haijun , Ullah Sadeeq , Liu Luo
Published: July 2022

The use of medical devices for therapeutic and diagnostic purpose is globally increasing; however, bacterial colonization on therapeutic devices can occur, causing severe infections in the human body. It has become an issue for public health. It is necessary to develop a nanomaterial based on photothermal treatment to kill toxic bacterial strains. Appropriately, high photothermal conversion and low-cost powerful photothermal agents have been investigated. Recently, gold nanocomposites have attracted great interest in biological applications. Here, we prepared rod-shaped Se-Te@Au nanocomposites of about 200 nm with uniform shape and surface-coated with gold nanoparticles for the first time showing high anti-bacterial and anti-cancer activities. Se-Te@Au showed proper structural consistency and natural resistance to bacterial and cancer cells. The strong absorption and high photothermal conversion efficacy made it a good photothermal agent material for the photothermal treatment of bacterial and cancer cells. The Se-Te@Au rod showed excellent anti-bacterial efficacy against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus, with highest recorded inhibition zones of 25 ± 2 mm and 22 ± 2 mm, respectively. More than 99% of both types of strains were killed after 5 min with a near-infrared (NIR) laser at the very low concentration of 48 µg/mL. The Se-Te@Au rod’s explosion in HeLa cells was extensively repressed and demonstrated high toxicity at 100 µg/mL for 5 min when subjected to an NIR laser. As a result of its high photothermal characteristics, the exceptional anti-bacterial and anti-cancer effects of the Se-Te@Au rod are considerably better than those of other methods previously published in articles. This study could open a new framework for sterilization applications on the industrial level.
Hot Tensile Deformation Behavior of Ti-6Al-4V Titanium Alloy Made by Laser Melting Deposition
Authors: Lv Haiyang , Li Dongsheng , Li Yong , Li Xiaoqiang
Published: July 2022

The combined process of additive manufacturing (AM) and subsequent hot forming technology enables the low-cost and rapid manufacturing of complicated structures with local features that cannot be manufactured monolithically by traditional forming technologies. The thermal deformation properties of as-deposited materials from AM require investigation. In this paper, laser melting deposition (LMD) was used to prepare as-deposited Ti-6Al-4V samples; high-temperature tensile tests for as-deposited titanium alloy were performed at different strain rates (0.001 s−1, 0.005 s−1, 0.01 s−1) and temperatures (650 °C, 700 °C, 750 °C) using the electrically assisted high-temperature tensile test system. The results show that the material’s flow stress level was negatively correlated with temperature and positively correlated with strain rate. EBSD and TEM were used to characterize the microstructure of the samples. The acicular martensite in the original material began to disintegrate under the influence of high-temperature tension, coarsening the lamella and splitting the boundary. The proportion of high-angle grain boundaries after deformation increased significantly from 81.4% to 87.5–90.7%. The results of the micromorphology observations indicate that the micro-deformation mechanism for deposited Ti-6Al-4V samples at high temperatures is mostly discontinuous dynamic recrystallization and dynamic spheroidization.
Solving Rescheduling Problems in Dynamic Permutation Flow Shop Environments with Multiple Objectives Using the Hybrid Dynamic Non-Dominated Sorting Genetic II Algorithm
Authors: Valledor Pablo , Gomez Alberto , Puente Javier , Fernandez Isabel
Published: July 2022

In this work, we seek to design a model that contributes to the study and resolution of a multi-objective rescheduling problem in dynamic permutation flow shop contexts. In this type of problem, where the objectives can be valued in heterogeneous units, the difficulty of achieving an optimal solution leads to finding a set of non-dominated efficient solutions (also called Pareto front). On the other hand, we will also consider the potential appearance of disruptions in planned scheduling (such as machine breakdowns or arrival of new priority jobs) that require a rapid re-planning of the aforementioned scheduling. In this paper, a hybrid dynamic non-dominated sorting genetic II metaheuristic (HDNSGA-II) is proposed to find the optimal Pareto front. The algorithm is applied to a benchmark already tested in previous studies, defined by three conflicting objective functions (makespan, total weighted tardiness, and stability) and three different types of disruption (machine breakdowns, incorporation of new jobs, and modifications in process times). According to the statistical comparison performed, the HDNSGA-II algorithm performs better in the designed environment, especially in larger problems.
Improving Cancer Metastasis Detection via Effective Contrastive Learning
Authors: Zheng Haixia , Zhou Yu , Huang Xin
Published: July 2022

The metastasis detection in lymph nodes via microscopic examination of H&E stained histopathological images is one of the most crucial diagnostic procedures for breast cancer staging. The manual analysis is extremely labor-intensive and time-consuming because of complexities and diversities of histopathological images. Deep learning has been utilized in automatic cancer metastasis detection in recent years. The success of supervised deep learning is credited to a large labeled dataset, which is hard to obtain in medical image analysis. Contrastive learning, a branch of self-supervised learning, can help in this aspect through introducing an advanced strategy to learn discriminative feature representations from unlabeled images. In this paper, we propose to improve breast cancer metastasis detection through self-supervised contrastive learning, which is used as an accessional task in the detection pipeline, allowing a feature extractor to learn more valuable representations, even if there are fewer annotation images. Furthermore, we extend the proposed approach to exploit unlabeled images in a semi-supervised manner, as self-supervision does not need labeled data at all. Extensive experiments on the benchmark Camelyon2016 Grand Challenge dataset demonstrate that self-supervision can improve cancer metastasis detection performance leading to state-of-the-art results.
Analysis of Different Image Enhancement and Feature Extraction Methods
Authors: Lozano-Vázquez Lucero Verónica , Miura Jun , Rosales-Silva Alberto Jorge , Luviano-Juárez Alberto , Mújica-Vargas Dante
Published: July 2022

This paper describes an image enhancement method for reliable image feature matching. Image features such as SIFT and SURF have been widely used in various computer vision tasks such as image registration and object recognition. However, the reliable extraction of such features is difficult in poorly illuminated scenes. One promising approach is to apply an image enhancement method before feature extraction, which preserves the original characteristics of the scene. We thus propose to use the Multi-Scale Retinex algorithm, which is aimed to emulate the human visual system and it provides more information of a poorly illuminated scene. We experimentally assessed various combinations of image enhancement (MSR, Gamma correction, Histogram Equalization and Sharpening) and feature extraction methods (SIFT, SURF, ORB, AKAZE) using images of a large variety of scenes, demonstrating that the combination of the Multi-Scale Retinex and SIFT provides the best results in terms of the number of reliable feature matches.
Block Kaczmarz–Motzkin Method via Mean Shift Clustering
Authors: Liao Yimou , Lu Tianxiu , Yin Feng
Published: July 2022

Solving systems of linear equations is a fundamental problem in mathematics. Combining mean shift clustering (MS) with greedy techniques, a novel block version of the Kaczmarz–Motzkin method (BKMS), where the blocks are predetermined by MS clustering, is proposed in this paper. Using a greedy strategy, which collects the row indices with the almost maximum distance of the linear subsystem per iteration, can be considered an efficient extension of the sampling Kaczmarz–Motzkin algorithm (SKM). The new method linearly converges to the least-norm solution when the system is consistent. Several examples show that the BKMS algorithm is more efficient compared with other methods (for example, RK, Motzkin, GRK, SKM, RBK, and GRBK).
Clavicular Malignancies: A Borderline Surgical Management
Authors: Nistor Claudiu-Eduard , Ciuche Adrian , Cucu Anca-Pati , Serban Bogdan , Cursaru Adrian , Cretu Bogdan , Cirstoiu Catalin
Published: July 2022

Nearly 1% of all bone cancers are primary clavicular tumors and because of their rarity, treating clinicians are unfamiliar with their diagnosis, classification, treatment options, and prognosis. In terms of preserving function and avoiding complications, clavicle reconstruction seems logical; however, further studies are needed to support this measure. Reconstruction techniques are difficult taking into account the anatomical structures surrounding the clavicle. When chest wall defects are present, a multidisciplinary team, including an orthopedist and thoracic and plastic surgeons, is of paramount importance for optimal surgical management. Malignant clavicle tumors may include primary and secondary malignancies and neighboring tumors with clavicular invasion. Surgical resection of complex thoracic tumors invading the clavicles can result in larger defects, requiring chest wall reconstruction, which is a substantial challenge for surgeons. Correct diagnosis with proper preoperative planning is essential for limiting complications. Post-resection reconstruction of the partial or total claviculectomy is important for several reasons, including maintaining the biomechanics of the scapular girdle, protecting the vessels and nerves, reducing pain, and maintaining the anatomical appearance of the shoulder. The chest wall resection and reconstruction techniques can involve either partial or full chest wall thickness, influencing the choice of reconstructive technique and materials. In the present paper, we aimed to synthesize the anatomical and physiopathological aspects and the small number of therapeutic surgical options that are currently available for these patients.
Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview
Authors: Stănescu Ana Maria Alexandra , Cristea Ana-Maria-Antoaneta , Bejan Gabriel Cristian , Vieru Mariana , Simionescu Anca Angela , Popescu Florin-Dan
Published: July 2022

The dysfunctionality of the protective skin barrier in psoriasis allows easier cutaneous penetration of various contact haptens; thus, such patients can develop allergic contact hypersensitivity as a comorbidity. Both skin conditions involve T-cell-mediated mechanisms. Dermatologists and allergists should consider assessing allergic contact cell-mediated hypersensitivity in selected psoriasis patients, especially those with palmoplantar psoriasis and who are refractory to topical treatments, and in patients with psoriasis, with or without arthritis, treated with biologics that present skin lesions clinically suggestive of contact dermatitis.
Paroxysmal Finger Hematoma—A Probable Vascular Disorder in Post-COVID-19 Condition: Two Clinical Case Presentations
Authors: Abrashev Hristo , Ananiev Julian , Georgieva Ekaterina
Published: July 2022

Background and Objectives: Achenbach’s syndrome is usually a benign, self-limiting clinical condition presented with finger discoloration, pain, and edema. Etiology, pathogenesis, and incidence remain unknown due to the variety of clinical features and the diversity of disease states leading to digital ischemia. COVID-19 primarily affects microcirculation, causing endothelial damage and disseminated microthrombosis. Materials and Methods: We reviewed two cases of Caucasian women with Achenbach’s syndrome after COVID-19 infection recovery between April and May 2021. Results: Here are presented two extremely rare cases of paroxysmal finger hematoma in two female patients after COVID-19 infection recovery. Conclusions: The exact etiology and pathophysiology of Achenbach’s syndrome remain unclear. It is assumed that SARS-CoV-2 infection could be the triggering factor in the pathophysiological mechanism of paroxysmal finger hematoma. We highly recommend the implication of the synthetic prostacyclin receptor agonist (Iloprost) as a first-line conservative treatment in patients with Achenbach’s syndrome and COVID-19 infection recovery.
Deep Cervical Muscles and Functionality in Patients with Chronic Tension-Type Headache: An Observational Study
Authors: García-Pérez-de-Sevilla Guillermo , Gónzalez-de-la-Flor Ángel , Martín-Vera Daniel , Domínguez-Balmaseda Diego , del-Blanco-Muñiz José Ángel
Published: July 2022

Background and objectives: Chronic tension-type headache (TTH) is the type of headache with the highest prevalence. The involvement of musculoskeletal structures in TTH is supported by evidence in the scientific literature. Among these, deep cervical muscle strength appears to be related to the function of the cervical spine and the clinical characteristics of TTH. This study aimed to correlate anatomical, functional, and psychological variables in patients with TTH. Materials and methods: An observational descriptive study was carried out with 22 participants diagnosed with TTH for at least six months. The characteristics of headaches, including ultrasound-based deep neck flexor and extensor muscle thickness, range of motion (ROM), and pressure pain threshold (PPT), were recorded. We also conducted the Pain Vigilance and Awareness Questionnaire (PVAQ) and the Craniocervical Flexion Test (CCFT). Results: Moderate–large negative correlations were found between the PVAQ and the muscle thickness of right deep flexors contracted (r = −0.52; p = 0.01), left multifidus contracted (r = −0.44; p = 0.04), right multifidus at rest (r = −0.48; p = 0.02), and right multifidus contracted (r = −0.45; p = 0.04). Moderate–large positive correlations were found between the CCFT score and the left cervical rotation ROM (r = 0.53; p = 0.01), right cervical rotation ROM (r = 0.48; p = 0.03), muscle thickness of left multifidus contracted (r = 0.50; p = 0.02), and muscle thickness of right multifidus at rest (r = 0.51; p = 0.02). The muscle thickness of the contracted right deep cervical flexors showed a moderate negative correlation with headache intensity (r = −0.464; p = 0.03). No correlations were found between PPT and the rest of the variables analyzed. Conclusions: In patients with TTH, a higher thickness of deep cervical muscles was associated with higher ROM and higher scores in the CCFT. In turn, the thickness of deep cervical muscles showed negative correlations with pain hypervigilance and headache intensity. These results contribute to a better understanding of the physical and psychosocial factors contributing to the development of TTH, which is useful for implementing appropriate prevention and treatment measures.