bluuebunny/crossref_metadata_2025 huggingface dataset:
Retirando a poeira: um caminho histórico para o reconhecimento do carnaval em Joinville como uma manifestação cultural
Authors: De Carvalho Silva Gusso Luana , Coutinho Joceli Fabrício
Published: December 2020

O presente artigo tem como propósito apresentar os vestígios históricos do Carnaval como uma festa popular na cidade Joinville, em Santa Catarina, entre o final do século XIX e início do século XX, a partir fontes documentais coletadas no Arquivo Histórico Municipal da cidade. A proposta busca problematizar o Carnaval como uma manifestação cultural da cidade apresentado por meio das notícias de jornais vinculadas a respeito dos belos corsos e préstitos que passaram pela ainda Colônia Dona Francisca, um fato que contrasta com a imagem sisuda e do atual momento em que o Carnaval não figura como um discurso de festa popular na cidade. Ainda, no recorte histórico proposto, discute-se como no momento momesco, Joinville como se esforçava para acompanhar as “tendências” carnavalescas dos grandes centros urbanos como o Rio de Janeiro e Recife. Nesse sentido, o artigo reflete como o Carnaval foi, e, infere-se que ainda é, uma manifestação cultural importante na cidade, sendo abrigado pelos artigos 215 e 216 da Constituição Federal de 1988. Diante das análises realizadas, pode-se sugerir que o Carnaval é uma festa popular na cidade de Joinville, e, como tal, é um direito cultural de sua população apoiado por sua historicidade apenas adormecida por camadas de poeira.
The Reform and Research of Class Teaching Under University-Enterprise Co-construction Mode
Authors: Dong Changzi
Published: December 2020

Under the background of the transformation and development of local colleges and universities, by investigating the concrete problems in the implementation process of the joint construction of colleges and enterprises in Longdong University, this paper puts forward that local colleges and universities should reform the traditional class teaching mode and properly revise teaching and training objectives based on the demand of enterprises, so as to achieve a win-win results.
Analysis of the Countermeasures of Dealing with the Network Public Opinions on Emergencies of Colleges in Gansu Province
Authors: Duo Jianwen , Wang Jin , Zhan Zhengyan , Yang Pinghui
Published: December 2020

The popularity of the Internet and the rise of self-media have built a diversified, convenient and instant platform for colleges and universities to do a good job in education, teaching, propaganda and ideology, but at the same time it also brings challenges and problems of college network security and campus stability. Most emergencies in colleges and universities are caused by trivial incidents and are largely unpredictable. If they are put online through online channels, they will attract the attention of the majority of netizens in a short period of time and attract online public attention. Once it is not handled in a timely manner, it will affect the normal education and teaching of colleges and universities and the safety and stability of campuses, and it is likely to form major public opinion on a larger scale, affecting the harmony and stability of the local society. This article adopts the characteristics of the network public opinion of colleges and universities in Gansu Province. It analyzes the current situation and focuses on the countermeasures to deal with network public opinion caused by emergencies in colleges and universities, hoping to provide a reference for further promoting the level and effectiveness of network public opinion in response to emergencies in Gansu Province.
On the Application of Information Technology in the Teaching of Ancient Poetry Recitation
Authors: Liu Hongxia
Published: December 2020

Ancient poetry recitation teaching, as a course that requires high human literacy, emotional expression and knowledge reserve, how to enable teachers to improve the teaching mode and construct a recitation classroom that can more inspire students to learn initiative, has become a need Problems that the ancient Chinese teachers in universities and colleges focus on solving. This article starts with the importance of introducing information technology in ancient poetry recitation classes in colleges and universities, looking for specific teaching models, hoping to provide suggestions for other teachers.
A Pandemia do Covid-19 e o Descortinamento das Vulnerabilidades da População LGBTQI+ Brasileira
Authors: MIRANDA MARCELO HENRIQUE GONÇALVES DE , GRANJEÃO FERNANDA DO NASCIMENTO , MONTENEGRO FRANCISCO FERREIRA PIRES DE ALBUQUERQUE
Published: December 2020

RESUMOO artigo tem como objetivo mapear as facetas de vulnerabilidade que marcam o público LGBTQI+ brasileiro, potencializadas pela pandemia do SARS-CoV-2. A partir da Análise de Conteúdo se buscou categorizar as mensagens veiculadas nos dados coletados pelo Coletivo #VoteLGBT (2020), nos dados produzidos pela OutRight Action International e nos dados da Associação Nacional de Travestis e Transexuais, a fim de identificar pontos nodais de vulnerabilidade notáveis à população LGBTQI+ brasileira e demonstrar um padrão de vulnerabilidade e de invisibilidade que ressoa e encontra semelhança em outros países. Perspectivas teóricas contemporâneas abordadas no estudo apontam que em um cenário permeado por tradições coloniais, exploratórias e discriminatórias há uma diferenciação entre vidas que merecem ser preservadas e vidas que são descartáveis. Por fim, foram trazidas iniciativas capitaneadas pela sociedade como boas práticas para evitar a perpetuação do silenciamento das vozes LGBTQI+.Palavras-chave: Covid-19. LGBTQI+. Vulnerabilidades. Pandemia. SARS-CoV-2 The Covid-19 Pandemic and the Exposure of the LGBTQI + Brazilian Population VulnerabilitiesABSTRACT The article aims to map the vulnerability facets that mark Brazilian LGBTQI+ public, enhanced by the SARS-CoV-2 pandemic. Based on Content Analysis, the messages conveyed in the data collected by the Collective #VoteLGBT (2020), by OutRight Action International and by the National Association of Transvestites and Transsexuals were categorized in order to identify nodal points of vulnerability notable to LGBTQI + Brazilian population, demonstrating a pattern of vulnerability and invisibility that resonates and finds similarity in other countries. Contemporary theoretical perspectives addressed in the study point out that in a scenario permeated by colonial, exploratory and discriminatory traditions, there is a differentiation between lives that deserve to be preserved and lives that are disposable. Finally, initiatives led by society were brought up as good practices to avoid the perpetuation of the silencing of LGBTQI + voices.Keywords: Covid-19. LGBTQI+. Vulnerabilities. Pandemic. SARS-CoV-2.
Psychological well-being and their relationship with different referents and sources of happiness in Chile
Authors: Moyano-Diaz Emilio , Mendoza-Llanos Rodolfo , Paez-Rovira Darío
Published: December 2020

The association between nine philosophical referents of happiness and well-being was examined in a convenience sample (n= 1060) of two Chilean cities. Participants had to choose one referent and respond to well-being, satisfaction, and happiness scales regarding family, friends, work, and leisure. A lower educational level was associated more with the referents Tranquility and Stoicism and less with the realization of capabilities. Young people ascribe more to the referents Satisfaction and Carpe Diem. Multiple hierarchical regressions considering well-being as a predicted variable showed that the Satisfaction and Affiliation referents were associated with greater psychological well-being. These results and the differences between the happiness referents chosen according to the controlled variables are discussed.
Technical framework for wastewater-based epidemiology of SARS-CoV-2 based on relative quantification via qPCR
Authors: Wu Jinyong , Wang Zizheng , Lin Yufei , Zhang Lihua , Chen Jing , Li Panyu , Liu Wenbin , Wang Yabo , Yao Changhong , Yang Kun
Published: December 2020

The global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has greatly affected people’s normal production, living, social and economic activities. Wastewater-based epidemiology (WBE) is expected to become a powerful tool to monitor the dissemination of SARS-CoV-2 at the community level, which has attracted the attention of scholars all over the world. However, there is not yet a standard protocol to guide its implementation. In this paper, we attempt to propose a technical framework of relative quantification for determining the virus abundance in wastewater and estimating the infection rate in corresponding communities, which is expected to achieve horizontal and vertical comparability in virtue of human-specific biomarkers as internal references. A comprehensive theoretical framework for relative quantification of viruses by qPCR is provided and discussed in detail. Critical factors affecting the virus detectability in wastewater and the estimation of infection rate include virus concentration methods, lag-period, per capita virus shedding amount, sewage generation rate, temperature-related decay kinetics of virus/biomarkers in wastewater, and hydraulic retention time (HRT), etc. Theoretical simulation shows that the main factors affecting the detectability of virus in sewage are per capita virus shedding amount and sewage generation rate. While the decay of SARS-CoV-2 in sewage is a relatively slow process, which has limited impact on its detection. Under the ideal condition of high per capita virus shedding amount and low sewage generation rate, WBE can give early warning for single infected person among 400,000 people.
Exploring Quantitative Metagenomics Studies using Oxford Nanopore Sequencing: A Computational and Experimental Protocol
Authors: ALILI Rohia , BELDA Eugeni , CLEMENT Karine , Le Phuong , PRIFTI Edi , ZUCKER Jean-Daniel , WIRTH Thierry
Published: December 2020

Background: The gut microbiome plays a major role in chronic diseases, several of which are characterized by an altered diversity and composition of bacterial communities. Large-scale sequencing projects allowed the characterization of these microbial community perturbations. However, a gap remains in how these discoveries can be translated into clinical applications. To facilitate routine implementation of microbiome profiling in clinical settings, portable, real-time, and low-cost sequencing technologies are needed.Results: Here, we propose a computational and experimental protocol for whole genome quantitative metagenomics studies of the human gut microbiome with Oxford Nanopore sequencing technology (ONT). We developed a bioinformatic pipeline to process ONT sequences based on the evaluation of different alignment parameters in the estimation of microbial diversity and composition. We also optimized stool collection and DNA extraction methods to maximize read length, a critical parameter for the sequence alignment and classification. Our analytical pipeline was evaluated using simulations of metagenomic communities to reflect naturally occuring compositional variations. We then validated our experimental and analytical pipeline with stool samples from a bariatric surgery cohort sequenced with ONT and Illumina, revealing comparable diversity and microbial composition profiles. These results were compared to those previously obtained with SOLiD sequencing, where differences were observed, possibly explained by variations in library preparation steps. Finally, we found that sequences obtained with ONT allowed assembly of complete genomes for disease-related species.Conclusion: This protocol can be implemented in the clinical or individual setting, bringing rapid personalized whole genome profiling of target microbiome species. Keywords: quantitative metagenomics, microbiome, obesity, gut microbiota, microbial DNA extraction, sequencing, Simulation, Oxford Nanopore Technologies, MinION.
Factors affecting utilization of sexual and reproductive health services among women with disabilities- A mixed-method cross-sectional study from Ilam district, Nepal
Authors: Shiwakoti Rupa , Gurung Yogendra Bahadur , Pathak Ram Sharan , Poudel Ram Chandra , Neupane Sandesh , Thapa Ram Krishna , Deuja Sailendra
Published: December 2020

Background
Despite Sustainable Development Goals explicit call for ensuring “Universal access to Sexual and Reproductive Health(SRH)”, and specific articles in the United Nations Convention on the Rights of Persons with Disabilities, women with disabilities(WwD) continue to experience barriers to access SRH services in Nepal. This study assessed factors affecting utilization of SRH services among WwD in Ilam district, Nepal.
Methods
A mixed method cross-sectional study of 384 WwD of reproductive age was conducted in Ilam district, Nepal. Face-to-face interviews were conducted using structured questionnaire. Relationships between utilization of SRH services and associated factors were explored using multivariate logistic regression. In-depth interviews of WwD, key informant interviews of health workers and local political leaders, and focus group discussions with Female Community Health Volunteers were used to collect qualitative data and underwent thematic analysis. Data were analyzed using Health Belief Model.
Results
One in five (15%) WwD had ever utilized SRH services. No need of (57%) and unaware of SRH services (24%) were main reasons for not utilizing SRH services. Majority (81%) of them reported that nearest health facility was not disability-friendly (73%) specifically referring to road (48%). A multivariate analysis showed factors positively associated with utilization of SRH services that included being ever-married (AOR = 121.7, 95% CI: 12.206-1214.338), perceived need of SRH services (AOR = 5.5; 95% CI: 1.419–21.357) and perceived susceptibility to SRH related disease/condition (AOR = 6.0; 95% CI:1.978–18.370). Qualitative findings revealed illiteracy, low economic and social class, lack of information, severity of disability, lack of disability friendly environment (no family support, distant health facility, inaccessible-infrastructure, stigmatization, bad behavior and attitude of health care providers), perception that SRH is needed only for married, and negative individual perception towards SRH (no need of SRH services, not susceptible to SRH related disease/condition and SRH disease/condition is not severe) as barriers to utilization of SRH services among WwD.
Conclusions
Utilization of SRH services among WwD was very low in Ilam district, Nepal. Promoting awareness raising program, ensuring disability-friendly environment, and prioritizing SRH services irrespective of marital status could increase SRH service utilization among WwD.
Research and Development of an Augmented Reality Visual Image-Guided Radiotherapy Positioning Technology
Authors: Chunying Li , Zhenda Lu , Mu He , Jianfeng Sui , Tao Lin , Kai Xie , Jiawei Sun , Xinye Ni
Published: December 2020

Objective: This study is conducted to explore the development of a noninvasive and nonradiative guided radiotherapy positioning system based on augmented reality (AR) technology to increase positioning accuracy and completely eradicate positioning errors.Method: The development system includes three monitors and supporting equipment. The 3D virtual model is obtained by 3D reconstruction of the radiotherapy plan data set and is superimposed on the correct treatment position of the real treatment environment by using augmented reality production software. This approach provides the standard for the patient's positioning and guides the patient. The position of the patient then coincides with the 3D virtual model through the visual image method, and positioning error of the radiotherapy position is reduced.Results: A total of nine cases are included in this study, namely, three patients who require head and neck radiotherapy and six patients who require chest and abdomen radiotherapy. According to experimental results, no statistical difference exists between AR-guided positioning and manual positioning for patients requiring head and neck radiotherapy. However, AR-guided positioning can keep errors of x-axis, y-axis and z-axis within small ranges, such as -0.092–0.072, -0.052–0.228, and -0.192–0.05 cm, respectively. For patients requiring chest and abdomen radiotherapy, AR-guided positioning is not statistically different from manual positioning on the x-axis, but statistical differences were found on the y-axis and z-axis. The errors of AR-guided positioning on y-axis and z-axis are much smaller than those of manual positioning.Conclusions: The AR visual image guided radiotherapy set-up system can increase radiotherapy positioning accuracy well, especially for patients requiring chest and abdomen radiotherapy.
Molecular Epidemiology Characteristics of Brucella Abortus Strains in China and Their Relationships With World Lineages
Authors: Wang Xu-Ming , Zhao Zhongzhi , Wang Miao , Cui Buyun , Liu Zhiguo , Li Zhenjun
Published: December 2020

Background Brucella abortus is a facultative intracellular Gram-negative bacterium that causes chronic persistent infections in humans and livestock. In this study, conventional bio-typing, multiple-locus variable-number tandem repeat analysis (MLVA), and whole-genome sequencing-single-nucleotide polymorphism (WGS-SNP) were used to investigate the molecular epidemiology characteristics of Brucella abortus strains in China and their relationships to world lineages. Results A total of 100 strains were collected from 1953 to 2013, suggesting that B. abortus circulated in China in the past five decades. Moreover, most strains were mainly distributed in the Northwest areas, suggest that provinces in the Northwest were a dominant epidemic area of this disease. During this period, seven biovars were found, indicating that B. abortus had a high diversity of biovars and it is also a potential reason for the disease ongoing spread in the Northern provinces. Strains have high genetic diversity, and bruce07 is the most helpful locus for genotyping of this population. Moreover, 17 MLVA-11 genotypes were found; 13 of them are of known genotypes and four are unassigned genotypes, indicating that B. abortus in this study had several geographic origins. Still, strains from unassigned genotypes may originate from China. Many shared MLVA-16 genotypes were observed in strains from the same provinces in Northern China, which confirmed a B. abortus brucellosis outbreak within Northern regions. WGS-SNP analysis showed that eight Chinese strains formed a ladder-like phylogram (C. Ⅶ) with strains from nine countries, including Uganda, Iraq, Russia, Georgia, Spain, Italy, Egypt, Mongolia, and China; suggest that strains were introduced to these countries from a single source. Conclusions Chinese B. abortus strains had high biovars and genetic diversity as well as represent characteristics of multiple geographic origins, and B. abortus strains from several mainly epidemic areas were closely related to strains from Russia and Mongolia; frequent animal (cattle) trade and exchanges may promote this process. We will provide new and valuable information to strengthening surveillance and control of B. abortus brucellosis in China.
Increased Frequency of β Cells with Abnormal NKX6.1 Expression in Type 2 Diabetes but not in Subjects with Higher Risk for Type 2 Diabetes
Authors: Liu Tengli , Sun Peng , Zou Jiaqi , Wang Le , Wang Guanqiao , Liu Na , Liu Yaojuan , Ding Xuejie , Zhang Boya , Liang Rui , Wang Shusen , Shen Zhongyang
Published: December 2020

Background: NKX6.1 is a transcription factor for insulin, as well as a marker for β cell maturity. Abnormal NKX6.1 expression in β cells, such as translocation from the nucleus to cytoplasm or lost expression, has been shown as a marker for β cell dedifferentiation.Methods: We obtained pancreatic sections from organ donors and immunofluorescence staining with NKX6.1 and insulin was performed to characterize NKX6.1 expression in subjects with or without type 2 diabetes mellitus (T2DM).Results: Our results showed that cells with insulin expression but no nucleic NKX6.1 expression (NKX6.1Nuc-Ins+), and cells with cytoplasmic NKX6.1 expression but no insulin expression (NKX6.1cytIns-) were significantly increased in T2DM subjects and positively correlated with glycated hemoglobin (HbA1c), indicating the elevated β cell dedifferentiation with NKX6.1 inactivation in T2DM. To investigate whether β cell dedifferentiation has initiated in subjects with higher risks for T2DM, we next analyzed the association between β-cell dedifferentiation level in ND subjects with different ages, body mass index, and HbA1c. The results showed the absolute number and percentage of dedifferentiated β cells with NKX6.1 inactivation did not significantly change in subjects with advanced aging, obesity, or modest hyperglycemia, indicating that the β cell dedifferentiation might mainly occur after T2DM was diagnosed.Conclusion: Our results suggested that NKX6.1 expression in β cells was changed in type 2 diabetic subjects, evidenced by significantly increased NKX6.1Nuc-Ins+ and NKX6.1cytIns- cells. This abnormality did not occur more frequently in subjects with a higher risk for T2DM, suggesting that β cell dedifferentiation might be secondary to the pathological changes in T2DM.
PacBio full-length transcriptome of wild apple (Malus sieversii) provides insights into canker disease dynamic response
Authors: Liu Xiaojie , Li Xiaoshuang , Wen Xuejing , Zhang Yan , Ding Yu , Zhang Yiheng , Gao Bei , Zhang Daoyuan
Published: December 2020

Background: Cytospora canker is a serious disease in the stem of Malus sieversii, caused by Cytospora mali. However, little is known about the global response mechanism in M. sieversii to C. mali infection. Results: Phytohormone jasmonic acid (JA) and salicylic acid (SA) profiles and transcriptome analysis were used to elaborate on the dynamic response mechanism. We determined that the JA was initially produced to respond to the necrotrophic pathogen C. mali infection at the early response stage, then get synergistically transduced with SA to respond at the late response stage. Furthermore, we adopted Pacific Biosciences (PacBio) full-length sequencing to identify differentially expressed transcripts (DETs) during the canker response stage. We obtained 52,538 full-length transcripts, of which 8,139 were DETs. Total 1,336 lncRNAs, 23,737 alternative polyadenylation (APA) sites and 3,780 putative transcription factors (TFs) were identified. Additionally, functional annotation analysis of DETs indicated that the wild apple response to the infection of C. mali involves plant-pathogen interaction, plant hormone signal transduction, flavonoid biosynthesis, and phenylpropanoid biosynthesis. The co-expression network of the differentially expressed TFs revealed 264 candidate TF transcripts. Among these candidates, the WRKY family was the most abundant. The MsWRKY7 and MsWRKY33 were highly correlated at the early response stage, and MsWRKY6, MsWRKY7, MsWRKY19, MsWRKY33, MsWRKY40, MsWRKY45, MsWRKY51, MsWRKY61, MsWRKY75 were highly correlated at the late stage. Conclusions: The full-length transcriptomic analysis revealed a series of immune responsive events in M. sieversii in response to C. mali infection. The phytohormone signal pathway regulatory played an important role in the response stage. Additionally, the enriched disease resistance pathways and differentially expressed TFs dynamics collectively contributed to the immune response. This study provides valuable insights into a dynamic response in M. sieversii upon the necrotrophic pathogen C. mali infection, facilitates understanding of response mechanisms to canker disease for apple, and provides supports in the identification of potential resistance genes in M. sieversii.
Significance of 1,3,4-Oxadiazole Containing Compounds in New Drug Development
Authors: Rana Kavita , Salahuddin  , Sahu Jagdish K.
Published: December 2020

Background:

Oxadiazole core displays various pharmacological properties among five
membered nitrogen heterocyclic compounds, specially 1,3,4-oxadiazole containing molecules that
have occupied a particular place in the field of synthetic medicinal chemistry as surrogates (bioisosteres)
of carboxylic acids, carboxamides and esters. Moreover, they are having widespread kind
of applications in numerous zones as polymers, as luminescence producing materials and as electron-
transporting materials and corrosion inhibitors.

Methods:

This study contains comprehensive and extensive literature survey on chemical reactivity
and biological properties associated with 1,3,4-oxadiazole containing compounds.

Results:

This review summarises 1,3,4-oxadiazole moiety in numerous compounds with reported
pharmacological activity such as antiviral, analgesic and anti-inflammatory, antitumor, antioxidant,
insecticidal and anti-parasitic, etc. Nevertheless, ring opening reactions of the 1,3,4-oxadiazole
core have also made great attention, as they produce new analogues containing an aliphatic nitrogen
atom and to other ring systems.

Conclusion:

In relation to the occurrence of oxadiazoles in biologically active molecules, 1,3,4-
oxadiazole core emerges as a structural subunit of countless significance and usefulness for the development
of new drug aspirants applicable to the treatment of many diseases. It concludes that
1,3,4-oxadiazole core compounds are more efficacious and less toxic medicinal agents with respect
to new opinions in the search for rational strategies.
Anxiety and Sleep Disturbances Among Health Care Workers During the COVID-19 Pandemic in India: Cross-Sectional Online Survey (Preprint)
Authors: Gupta Bhawna , Sharma Vyom , Kumar Narinder , Mahajan Akanksha
Published: December 2020

BACKGROUND

The COVID-19 pandemic caused by SARS-CoV-2 has become a serious concern among the global medical community and has resulted in an unprecedented psychological impact on health care workers, who were already working under stressful conditions.

OBJECTIVE

In this study, we aimed to evaluate and measure the effects of the COVID-19 pandemic on the anxiety levels and sleep quality among health care workers in India, as well as to determine how the unavailability of personal protective equipment affects their willingness to provide patient-related care.

METHODS

We conducted an online cross-sectional study using piloted, structured questionnaires with self-reported responses from 368 volunteer male and female health care workers in India. Study participants were identified through social networking platforms such as Facebook and WhatsApp. The survey evaluated the participants’ degree of signs and symptoms of anxiety and sleep quality based on the 7-item Generalized Anxiety Disorder (GAD-7) scale and single-item Sleep Quality Scale, respectively. Information on the availability of personal protective equipment was collected based on responses to relevant survey questions.

RESULTS

The majority of health care workers (126/368, 34.2%) were in the age group 45-60 years, and 52.2% (192/368) were doctors. Severe anxiety (ie, GAD-7 score >10) was observed among 7.3% (27/368) health care workers, whereas moderate, mild, and minimal anxiety was observed among 12.5% (46/368), 29.3% (108/368), and 50.8% (187/368) health care workers, respectively. Moreover, 31.5% (116/368) of the health care workers had poor-to-fair sleep quality (ie, scores <6). Univariate analysis showed female gender and inadequate availability of personal protective equipment was significantly associated with higher anxiety levels (P=.01 for both). Sleep disturbance was significantly associated with age <30 years (P=.04) and inadequate personal protective equipment (P<.001). Multivariable analysis showed that poorer quality of sleep was associated with higher anxiety levels (P<.001).

CONCLUSIONS

The COVID-19 pandemic has potentially caused significant levels of anxiety and sleep disturbances among health care workers, particularly associated with the female gender, younger age group, and inadequate availability of personal protective equipment. These factors put health care workers at constant risk of contracting the infection themselves or transmitting it to their families. Early identification of at-risk health care workers and implementation of situation-tailored mitigation measures could help alleviate the risk of long-term, serious psychological sequelae as well as reduce current anxiety levels among health care workers.
Questions to the Article: Comparative Analysis of Search Strings in PubMed on the COVID-19 Pandemic (Preprint)
Authors: Yang Shao , Chien Tsair-Wei
Published: December 2020

BACKGROUND

The recent article published on November 27 in 2020 is well-written but remains several questionable issues that are required to clarifications further, particularly for readers who hope to replicate this study using a longer period of months instead of the original days from March 11 to May 19, 2020.

OBJECTIVE

Redo the study using a longer period of time to examine the difference from and similarity to the previous study and present results using visual representations.

METHODS

Similar search schemes were compared to the golden standard(LitCovid) using three metrics of sensitivity, precision, and F-score. We applied similar search schemes to extract publications related to COVID-19 from January to November in Pubmed Central(PMC). The Kano model was applied to present the study results divided into three groups of high sensitivity, high precision, and neutral. Comparison of publication counts was made using the line plot to display.

RESULTS

We observed that the comprehensive search scheme recommended by the original authors was ranked at the third placement instead of the first one shown in this study. A small number of articles extracted from the PMC were attributable to the reasons for schemes with (1) only one keyword of coronavirus, (2) that totally constrained by Wuhan, and (3) that hyphen and space misused in keyword terms. Scheme 2, authored by Shokraneh in the journal of BMJ, was ranked first, followed by Schemes 9 and 1 with F-scores at 97.9, 90.2, and 87.3, respectively. The single-term search COVID-19 performed best in terms of precision (99.9%) but not well in terms of sensitivity (76.6%) and F-score (86.7%). The term Wuhan virus performed the worst: 24.2% for sensitivity, 90.9% for precision, and 138.2% for F-score due to the reason for using AND condition in the search string. All 32 schemes were compared and displayed on the Kano diagram.

CONCLUSIONS

Different results were displayed using similar search schemes with a longer period of time from January to November in 2020. Scheme 2 is recommended for the bibliometric study related to COVID-19 in the future. The Kano diagram can be a visual display to compare search schemes based on precision(on Axis X), sensitivity(on Axis Y), and F-score(by bubble size) laid on a dashboard.

CLINICALTRIAL

Nil
Support Seeking in the Postpartum Period: Content Analysis of Posts in Web-Based Parenting Discussion Groups (Preprint)
Authors: Chivers Bonnie R , Garad Rhonda M , Moran Lisa J , Lim Siew , Harrison Cheryce L
Published: December 2020

BACKGROUND

The transition from pregnancy to motherhood is a major developmental phase that can be challenging for both women and their families. For new mothers, the postpartum period is recognized as a critical period for increased risk of both physical and mental health concerns. For this reason, it is imperative that women receive accurate, evidence-based information during this time.

OBJECTIVE

This study aims to explore the conversations of new mothers on a web-based parenting forum to investigate what topics or concerns are being discussed.

METHODS

A leading Australian web-based support forum for women before and after birth was used to obtain a sample of posts from the mothers of infants aged 0-12 months. Quantitative data (word frequencies and sentiment analysis) and qualitative data (post content) were extracted from discussion threads and examined to determine sentiments and theoretical storylines.

RESULTS

In total, 260 posts were sampled. Infant care was the most prominent overarching topic discussed, with feeding and sleep being the most discussed subtopics. Discussions about maternal care were much less frequent but included questions about birth recovery, breastfeeding concerns, and interconception. A pattern of behavior emerged within the posts. This pattern resembled a cycle of learning across five phases: help seeking, solution ideation, testing and skill development, consolidation, and empowerment and improved mental well-being. A dynamic interplay was observed as mothers navigated new concerns or developmental changes.

CONCLUSIONS

Engagement in web-based forums to seek help and support during the postpartum period was common, with infant health and well-being being the primary concerns for new mothers during this time. The identification of a maternal learning cycle within the forum underscores the contributory role of web-based communities in maternal peer social support, information seeking, and early parenting practices.

CLINICALTRIAL
ESTUDO DE CASO SOBRE UMA CRIANÇA COM TDAH: o diagnóstico clínico
Authors: Silva Cristiana Maria da , Mendes Delza Ferreira , Barbosa Deivid de Oliveira
Published: December 2020

Attention deficit hyperactivity disorder (ADHD) is a persistent pattern of neglect and/or hyperactivity-impulsivity that interferes with non-functioning or non-development of a person. The following article focuses on identifying the criteria for a child psychodiagnostic assessment that presents traces of TDHA and the effectiveness of diagnostic tests undertaken during this assessment process. For this purpose, an experience report of a clinical case was made and held in a Psychology Clinic of a Faculty of the Interior of Minas Gerais. The child was directed to psychological care, for presenting behaviors such as low school performance, wandering during the performance of tasks, lack of persistence, difficulty in keeping focused, disorganization and excessive motor activities and then another psychodiagnostic assessment was done. This case study makes possible to confirm and accompany the psychodiagnostic process of the country presenting a characteristic of ADHD found in bibliographic research and confirmed non-clinical psychodiagnostics.
Relationships between developmental feedback, intrinsic motivation, and creative personality and performance
Authors: Su Weilin , Lyu Bei , London Manuel
Published: December 2020

Developmental feedback can motivate employees to take chances and be more creative, at least for employees who interpret feedback as support for new ideas. Drawing on cognitive evaluation theory, we examined relationships between developmental feedback, intrinsic motivation, creative personality (e.g., people who describe themselves as inventive and confident rather than cautious and conservative), and creative performance. We predicted that developmental feedback would contribute to employees? intrinsic motivation and further improve their creative performance, especially those who were high in creative personality. The sample included 215 Chinese employees and their direct supervisors from a big science and technology corporation in Beijing, China. Employees? perceptions of developmental feedback from their supervisor were positively related to employees? ratings of their intrinsic motivation and supervisors? ratings of employees? creative performance. Also, intrinsic motivation of employees mediated the relationship between developmental feedback and their creative performance. These relationships were stronger for employees with a highly creative personality.
CONSTRUINDO A APRENDIZAGEM A PARTIR DO MUNDO DA ARTE, BRINCADEIRA E MUSICA
Authors: Martins Sandra da Silva
Published: December 2020

Este trabalho consiste no relato de um projeto educacional realizado com alunos do Pré II, em uma escola da rede Municipal da cidade de Jaguarão Rs. As práticas docentes foram desenvolvidas com os objetivos de analisar as contribuições dos planos de aulas organizados, a partir do principio do fio condutor “Construindo a Aprendizagem a Partir do Mundo da Arte, Brincadeira e Música”, a fim de provocar os alunos à reflexão para que reconstruíssem suas aprendizagens. Abordar-se-á, Metodologias e atividades desenvolvidas com a turma durante o projeto. Ao final de cada plano de aula é apresentado as reflexões acerca da prática docente e construção de aprendizagens pelos alunos. Para fundamentar utilizou-se o Referencial Curricular para a educação infantil (1998), Hernandez (1998), Tardif (2007). Este trabalho contribuiu para que todos os alunos se envolvessem com as atividades propostas, pois os conteúdos trabalhados apresentavam sentido para a vida dos mesmos. Com este percebeu-se a importância de organizar, planejar aulas que vão ao encontro do que o aluno já sabe, fazendo com que construam novos conhecimentos. Sendo assim, espera-se que por meio destas experiências no ambiente escolar, possa-se contribuir com reflexões para ampliar as questões que envolvem aulas planejadas a partir do tema Arte, Musica e brincadeiras. Palavras-Chave: Aprendizagem. Planejamento. Prática docente.
La Ley Micaela y el notariado
Authors: Barriviera Natalia Lorena
Published: December 2020

El presente artículo comienza con una ligera mención de los antecedentes de la Ley N° 27.499, principalmente el impacto que en la sociedad argentina produjo el femicidio de Micaela García, y la consecuente lucha por la visibilización de desigualdades y violencias que vienen realizando movimientos de mujeres y otras disidencias sexuales en nuestro país. Seguidamente se señala la importancia de la creación como cartera de estado al Ministerio de las Mujeres, Géneros y Diversidad por parte del Estado Nacional. Previamente a comenzar con el análisis en particular de la ley en el notariado, se reseñan algunos hitos importantes que fueron citados en los fundamentos del proyecto de ley, para comprender el espíritu de la misma. Se analizan las características y sistema del notariado que adopta nuestro país, que nos llevan a afirmar sin hesitaciones la obligatoriedad de capacitación en género de los notarios y las notarias, de conformidad a lo dispuesto por Ley Micaela, que se extienda esta capacitación hacia los empleados y empleadas de las notarías, y las consecuencias de la negativa en capacitarse. Por último, dejamos planteados algunos interrogantes con la intención de que sirvan como puntapié inicial para futuras reflexiones e instamos a los Colegios de Escribanos y al Consejo Federal del Notariado Argentino a asumir el compromiso de emprender el camino de la capacitación en género establecido por la Ley Micaela, transversalizando la perspectiva de género.
Serum Inflammation Markers in Tuberculosis
Authors: Kusnir P , Dohal M , Porvaznik I , Mokry J.
Published: December 2020

Tuberculosis remains one of the leading infectious cause of death in the world. The goals of screening are to detect active tuberculosis early enough and to identify individuals eligible for preventive therapy to reduce a po tential co-infection by tuberculosis. Plasma/serum screening for selected potential biomarkers could represent a suitable method of tuberculosis diagnosis and treatment outcome. Furthermore, monitoring of tuberculosis treatment is crucial to clinical decision-making and besides the plasmatic concentration of administered antituberculosis drugs, the biomarkers appear to play a significant role in the estimation of the real therapeutical impact.

The current standard remains focused on culture conversion, especially two-month culture status, which has a relatively low sensitivity. Identification of non-sputum-based biomarkers of the treatment respond would be beneficial for individual monitoring of tuberculosis patients.

This mini-review describes several serological/plasmatic markers that can be analyzed by simple immunoassays as ELISA method, e.g. C-reactive protein, soluble intercellular adhesion molecule-1, soluble urokinase plasminogen activator receptor, soluble lymphocyte activation gene-3, granzyme B and soluble tumor necrosis factor receptor one and two as reliable enough as an indicator of successful treatment of tuberculosis.
Effect of Chemically-Induced Diabetes Mellitus on Phenotypic Variability of the Enteric Neurons in the Descending Colon in the Pig
Authors: Bulc Michał , Całka Jarosław , Zielonka Łukasz , Dąbrowski Michał , Palus Katarzyna
Published: December 2020

Gastrointestinal neuropathy in diabetes is one of numerous diseases resulting in abnormal functioning of the gastrointestinal tract (GIT), and it may affect any section of the GIT, including the descending colon. In the gastrointestinal system, the neurons are arranged in an interconnecting network defined as the enteric nervous system (ENS) which includes the myenteric plexus and the submucosal plexuses: inner and outer. Regular functioning of the ENS is determined by normal synthesis of the neurotransmitters and neuromodulators. This paper demonstrates the effect of hyperglycaemia on the number of enteric neurons which are immunoreactive to: neural isoform of nitric oxide synthase (nNOS), vasoactive intestinal peptide (VIP), galanin (GAL), calcitonin generelated peptide (CGRP) and cocaine amphetamine-regulated transcript (CART) in the porcine descending colon. It was demonstrated that there was a statistically significant increase in the number of neurons within the myenteric plexus immunoreactive to all investigated substances. In the outer submucosal plexus, the CART-positive neurons were the only ones not to change, whereas no changes were recorded for nNOS or CART in the inner submucosal plexus. This study is the first study to discuss quantitative changes in the neurons immunoreactive to nNOS, VIP, GAL, CGRP and CART in the descending colon in diabetic pigs.
A note on nil-clean rings
Authors: Danchev Peter V.
Published: December 2020

We study a special kind of nil-clean rings, namely those nil-clean rings whose nilpotent elements are difference of two “left-right symmetric” idempotents, and prove that in some various cases they are strongly π-regular. We also show that all nil-clean rings having cyclic unit 2-groups are themselves strongly nil-clean of characteristic 2 (and thus they are again strongly π-regular).
On λD − R0 and λD − R1 spaces
Authors: Namiq Sarhad F. , Rosas Ennis
Published: December 2020

In this paper we introduce the new types of separation axioms called λD − R0 and λD − R1 spaces, by using λD-open set. The notion λD − R0 and λD − R1 spaces are introduced and some of their properties are investigated.
Some fixed point results on S-metric spaces
Authors: Shahraki Maryam , Sedghi Shaban , Aleomraninejad S. M. A. , Mitrović Zoran D.
Published: December 2020

In this paper, a general form of the Suzuki type function is considered on S- metric space, to get a fixed point. Then we show that our results generalize some old results.
Empirical Analysis of the Impact Strength of Textile Knitted Barrier Meshes
Authors: Mikołajczyk Zbigniew , Szałek Beata , Pieklak Katarzyna
Published: December 2020

The assumptions of instrumental methodology for measuring dynamic loads of knitted barrier meshes were defined. A test stand was built, original in terms of both mechanical construction and electronic measuring system, connected to a computer data analysis system. Maximum values of dynamic forces in the mesh fastening strings were determined. The correctness of the strain gauges construction and measurement data transmission systems was confirmed. Tests of multidirectional resistance to dynamic loads in the mesh fastening strings were carried out. The experiment involved dropping a ball with a mass of 5 kg and a diameter of 10 cm, from a height of 1 m and 2 m onto the mesh surface. The potential impact energy equaled Ep1 = 49.05 J and Ep2 = 98.1 J. The tests showed that the highest force values were observed for meshes with square-shaped a-jour structure, and for mesh with diamond-shaped a-jour geometry the force values were lower. A symmetrical forces distribution was observed in all the strings. The highest forces were recorded in the middle strings and the lowest in the outer ones. The conducted tests confirmed the correctness of the adopted constructional solutions of test stand for identification of dynamic stress distribution in mesh fastening strings. The developed method is a useful verification tool for numerical analysis of mechanical properties of barrier meshes.
Mobile Payment in the Connected Car: Developing Services Based on Process Thinking
Authors: Petry Lukas F. , Moormann Jürgen
Published: December 2020

Background

The automotive world is on the threshold of a new era. Manufacturers are transforming themselves into suppliers of mobility services. Fundamentals for the transformation are customer processes combined with connectivity driven by the Internet of Things. Mobile payment serves as an enabler to most of these services.

Objectives

This paper demonstrates promising ways how payment-enabled services in the context of connected cars can be designed based on the process thinking approach.

Methods/Approach

In this paper, the methodology of use cases is applied as a means to develop services for the connected car through process thinking. The use case studied is validated afterwards with industry experts following a semi-structured interview format.

Results

The use case investigated in the course of the paper suggests that the core characteristics and challenges of these services are already predictable ex-ante by the theoretical framework on which the paper is built upon. In particular, the paper shows the steps needed for a driver’s request for on-demand horsepower for a certain time span along with mobile payment for this service.

Conclusions

It is concluded that the connectivity paradigm supplemented by mobile payment options enables consistent implementation of customer centricity in terms of process thinking.
Axiological justification of the objective norm by Heinrich Rickert
Authors: Bobko Aleksander
Published: December 2020

The aim of this paper is to show the main thesis concerning the theory of cognition of the eminent neo-Kantian Heinrich Rickert, as presented in his work “Der Gegenstand der Erkenntnis”. On the one hand, Rickert finds out that thinking is fated to “clash with nothingness”, thus creating a temptation to reject all rigours and to yield to complete discretion. On the other hand, he attributes axiological status to nothingness which subjects thinking to a particular kind of “ought”. In his view, the cognizing subject is faced with an axiological choice: either discretion or truth and argues that it is worth opting for truth. His argumentation could be an interesting point of reference for contemporary culture gradually moving away from the type of thinking rooted in objectively existing principles.
Chessboard and Chess Piece Recognition With the Support of Neural Networks
Authors: Czyzewski Maciej A. , Laskowski Artur , Wasik Szymon
Published: December 2020

Chessboard and chess piece recognition is a computer vision problem that has not yet been efficiently solved. Digitization of a chess game state from a picture of a chessboard is a task typically performed by humans or with the aid of specialized chessboards and pieces. However, those solutions are neither easy nor convenient. To solve this problem, we propose a novel algorithm for digitizing chessboard configurations.

We designed a method of chessboard recognition and pieces detection that is resistant to lighting conditions and the angle at which images are captured, and works correctly with numerous chessboard styles. Detecting the board and recognizing chess pieces are crucial steps of board state digitization.

The algorithm achieves 95% accuracy (compared to 60% for the best alternative) for positioning the chessboard in an image, and almost 95% for chess pieces recognition. Furthermore, the sub-process of detecting straight lines and finding lattice points performs extraordinarily well, achieving over 99.5% accuracy (compared to the 74% for the best alternative).