bluuebunny/crossref_metadata_2025 huggingface dataset:
Islas Afortunadas: Canarias y su frontera
Authors:   Universidad de La Laguna (España), Martín Dávila Virginia
Published: June 2024

This article explores the semantic camp «Unfortunate Islands», which is evidence of a border within the semiosphere of the Canary Islands. This semantic camp arises from the tension caused by mass tourism in the Canary Islands and as an opposition to the name «Fortunate Islands», which the Canary Islands have historically received. From the perspective of the semiotics of culture, this border develops through a I-I communication system that ends up hatching in a self-description of the system. In order to highlight the internal border represented in the Canarian semiosphere by these two semantic fields, we will undertake a brief analysis of Los días del paraíso (León Barreto, 1988) and of some manifestations of activism in the Canary Islands.
Hegemonía patológica. Medicalización de los problemas sociales
Authors:   Universidad de La Laguna (España), Bastida Escribano Alberto
Published: June 2024

This study reflects on the socioeconomic profile of individuals who have initiated treatments related to mental health after the covid-19 pandemic, focusing on the case of the Canary Islands. Through a literature review and case analysis, the medicalization of social problems is questioned. Additionally, a model is presented that groups a series of social factors associated with the development or diagnosis of mental illnesses. This approach aims to go beyond mere medication prescription, exploring the connections between social contexts and mental health, advocating for the role that Sociology should play in the study of these realities.
Transgredir el modelo hegemónico de la masculinidad en la poesía. De Luis Cernuda a Ángelo Néstore
Authors:   Universidad de Málaga (España), Rodríguez Sánchez Francisco
Published: June 2024

This paper analyzes the representations of new masculinities and dissident identities in poetic texts written in Spanish in the 20th and 21st centuries, from Luis Cernuda to Ángelo Néstore, including Porfirio Barba-Jacob, Federico García Lorca, Leopoldo M.ª Panero and Ana Rossetti as representative authors of what has come to be considered queer literature. In this current, issues about the construction of the subject, corporeality, sex, categories and cultural institutions of the patriarchal and binary system are recognized and problematized. To this end, this study employs the methodological synergy of queer studies with literary criticism in order to expose and evaluate the literary manifestations of abject bodies in the Hispanic context.
O processo antimodernista da revista D. Quixote
Authors:   Universidade Federal do Estado do Rio de Janeiro (Brasil), Vergara Jorge Israel Ortiz
Published: June 2024

In Rio de Janeiro, under the control of Brazilian writer Manuel Bastos Tigre, the D. Quixote magazine (1917-1926) published prejudiced content aimed at critiquing the São Paulo modernist movement between 1920 and 1926. Employing humor along with textual and visual resources, D. Quixote conveyed ableism, misogyny, homophobia, racism, and the stigmatization of musical and popular practices. To qualify the intensity of prejudiced expression in publications of the process, the author defined the category of ‘expressive aggressiveness’. Due to the synchrony and similarity of part of the content, elements of D. Quixote’s process were compared with elements of the anti-modernist campaigns of the São Paulo newspapers A Gazeta (1921-1922) and Folha da Noite (1923). Utilizing keyword searches in the Digital Newspaper Library of the Brazilian National Library relevant publications were found. Likewise, the arguments of researchers in humor and Brazilian history were considered. This report records the names and artworks questioned at the reception of São Paulo modernism in Rio de Janeiro, shedding light about the social construction of prejudice. Notably, journalists, writers, and humorists engaged in producing prejudiced content as means to engage in debate about art.
Ultrasound-guided aspiration and barbotage of acute calcific tendonitis in unusual locations
Authors: Babhulkar Joban Ashish , Gaitonde Amith
Published: June 2024

Acute calcific tendonitis is an excruciatingly painful condition occurring due to the deposition of calcium, that is, calcium hydroxyapatite crystals within the tendons with subsequent rupture into the peritendinous tissues. The most common sites of calcific tendonitis are rotator cuff tendons, followed by the gluteal tendons in the hip. However, calcific tendonitis can occur in any tendons in the body. In this article, we present three unusual sites of acute calcific tendonitis with peritendinous rupture as diagnosed on high-resolution ultrasound (HRUS), along with its ultrasound-guided management. We should be familiar with these unusual sites and their management so that immediate relief and early recovery can be provided to the patient.
Arthroscopic intercruciate trans-septal posterior cruciate ligament avulsion fixation with pull-through technique using a single button adjustable loop device
Authors: Gupta Himanshu , Mittal Bharat Swaroop , Jain Vineet
Published: June 2024

Numerous arthroscopic techniques have been described for the fixation of posterior cruciate ligament avulsion, including the pull-out technique with suture or tape fixed with a knot tied over a free cortical button on the anterior tibial cortex, and the adjustable loop with double cortical buttons. We present a modification of the suture pull-out method utilizing the readily available adjustable loop with a single cortical loop button for fixation on the anteromedial tibial cortex. The surgery is performed through an intercruciate trans-septal approach with the suture bridge configuration and cross-over of suture tapes, with two diverging tibial tunnels with a single anterior opening forming a “Y-shaped tunnel.” The advantages of the suture pull-through method and the adjustable loop device can be combined using this technique modification.
Next-generation digital chest tomosynthesis
Authors: Gange Christopher , Ku Jamie , Gosangi Babina , Liu Jianqiang , Maolinbay Manat
Published: June 2024

The objective of this study was to demonstrate the performance characteristics and potential utility of a novel tomosynthesis device as applied to imaging the chest, specifically relating to lung nodules. The imaging characteristics and quality of a novel digital tomosynthesis prototype system was assessed by scanning, a healthy volunteer, and an andromorphic lung phantom with different configurations of simulated pulmonary nodules. The adequacy of nodule detection on the phantoms was rated by chest radiologists using a standardized scale. Results from using this tomosynthesis device demonstrate in plane resolution of 16lp/cm, with estimated effective radiation doses of 90% less than low dose CT. Nodule detection was adequate across various anatomic locations on a phantom. These proof-of-concept tests showed this novel tomosynthesis device can detect lung nodules with low radiation dose to the patient. This technique has potential as an alternative to low dose chest CT for lung nodule screening and tracking.
Switzerland and the Sustainable Development Goals of the United Nations from the youngSCS Perspective
Authors: Papadimou Chrysanthi , Geraci Gaetano F. , Schlemper-Scheidt Marie-Désirée
Published: June 2024

Switzerland’s commitment to the Sustainable Development Goals of the United Nations is showcased in this article with concrete examples of actions taken so far in the private and public sector. To further highlight the involvement of the chemical scientists in the implementation of the SDGs in Switzerland to date, the young-SCS also interviewed various individuals.
Contribution of the Swiss Chemistry Community to SDGs – Perspective of the SCNAT Platform Chemistry
Authors: Hofmann Sandra , Merz Leo
Published: June 2024

Sustainability has become indispensable – and so has the role chemistry plays in reaching the Sustainable Development Goals (SDGs). The Swiss Academy of Sciences (SCNAT) and its Platform Chemistry (PFC) can be a partner of the Swiss chemistry community in reaching (some of) these goals through their umbrella network. Next to all existing initiatives, SCNAT PFC recommends the chemistry community to support increasing scientific literacy such that for example students who want to contribute to a better environment in their future career become aware of the impact that chemistry has on sustainability and every day lives. The SDGs are a formalism that can be used to help communicating the impact of chemistry. It is important to keep on advertising also fundamental research, as this is the essential basis for any sustainable development.
From Plastic Models to Virtual Reality Headsets: Enhancing Molecular Structure Education for Undergraduate Students
Authors: Pimpasri Chaleena , Limpanuparb Taweetham
Published: June 2024

The comprehension of molecular structure is pivotal in chemistry education. Over the past decade, Mahidol University International College has employed various teaching tools for the introductory chemistry laboratory class. This paper outlines our evolutionary shift from traditional tools, such as plastic and plasticine models, to the integration of computer software, and ultimately to augmented reality (AR) and virtual reality (VR) tools—specifically, MoleculARweb and MolecularWebXR developed by École Polytechnique Fédérale de Lausanne researchers. In this paper, we detail the implementation of these tools in our classes and present the outcomes of student surveys. Our instructional focus encompasses VSEPR, Atomic Orbitals, Molecular Orbitals, Skeletal Formula, and Enantiomers. This paper not only serves as a model for educators in general chemistry at secondary school or university levels to incorporate technology into their classrooms but also showcases a collaborative endeavor between Swiss and Thai researchers.
Automation of determining the boundaries of river basins of small rivers: the case of Khangalassky district of the Sakha Republic (Yakutia)
Authors: Obutov K. A. , Danilov Yu. G.
Published: June 2024

Currently, the absence of a GIS system linked to river basins in Russia may complicate the work of important operational environmental and hydrometeorological surveillance services. It is important to note that simplifying and accelerating the allocation of river basins through open source software can significantly optimize the work of researchers, especially in conditions where it is important to respond promptly to floods and floods in a short time. The purpose of this work is to automate the allocation of river catchment areas, which can help in the study of vast territories of the Far East, as well as contribute to the creation of effective forecasting and monitoring systems. The study presents an automated approach to the identification of watersheds based on the use of geospatial data and information processing algorithms. The presented method demonstrates the effective allocation of watershed boundaries, which makes it possible to simplify the research process and increase the accuracy of the data obtained. The study was conducted within the boundaries of Khangalassky district of the SR(Ya). The data obtained using digital terrain models were corrected, and then used for rapid allocation of watersheds by means of an algorithm developed by the authors. The algorithm is a module for QGIS, which uses the QGIS and GDAL tools in turn, which significantly speeds up the process of creating materials for further research. The results of the study emphasize the accessibility of obtaining information about the geosystems of river basins as integral systems and put forward the prospect of improving GIS processes related to water resources for more effective monitoring of ecosystems and decision-making in the field of environmental protection.
Assessment of biogeocenosis quality within the boundaries of anthropogenic impact on the sustainability of an industrially developed territory
Authors: Yadrikhinskiy I. V. , Popova D. N. , Karamzin A. V. , Sivseva E. A. , Everstov N. V. , Levina S. N. , Davydova P. V. , Everstova A. A. , Egorov A. V.
Published: June 2024

Currently, the scientific community faces the task of identifying and minimizing the negative impact on the natural environment and related environmental risks caused by the impact on ecosystems, especially anthropogenic factors related environmental risks. The determining role in the assessment of environmental risk is to determine the probability of occurrence of effects of different nature in ecosystems because of anthropogenic factors and to take measures to prevent their negative impact. The purpose of the presented theoretical study was to study and analyze the principle of system-wide methodology of quantitative assessment of biogeocenosis quality within the boundaries of anthropogenic influence on the sustainability of industrially developed territory. The considered principle can provide prerequisites for making changes in the norms of nature management in Russia.
Current Trends in the Development of Russian Ethnomusicology
Authors: Лобкова Г.В.
Published: June 2024

В настоящее время особо актуальны вопросы истории этномузыкологии, связанные с деятельностью ведущих исследователей — собирателей музыкального фольклора и основателей научных школ. Данной проблематике посвящена главная часть тематического выпуска, обзор которого представлен в статье. Раскрытию ранее неизвестных страниц истории науки способствует обращение к обширной документальной базе: рукописям, аудиозаписям, фотографиям. Суммирование информации и  критический анализ источников позволяют прояснить события прошлого и дать верную оценку результатам деятельности ученых. Одним из перспективных историко-текстологических методов, применяемых в ряде работ, является сопоставление слуховых нотаций и фонограмм XIX — начала XX в. с аудиозаписями и их расшифровками, выполненными в 1970–80-е гг. и более позднее время. Сделанные на этой основе выводы касаются не только подходов к фиксации материалов, но и динамики изменения песенных традиций в целом. Весьма востребованы ареалогические изыскания, базирующиеся на результатах полевой работы многих поколений собирателей и  открывающие перспективу дальнейших исторических обобщений. Не менее актуальны проблемы использования музыкального фольклора в творчестве композиторов, а также применения в практике современных исполнителей способов музицирования, сложившихся в устной традиции.

At present, issues of the history of ethnomusicology related to the activities of leading researchers (collectors of musical folklore and founders of scientific schools) are especially relevant. The main part of the thematic issue of the journal, an overview of which is presented in this article, is devoted to this issue. The disclosure of previously unknown pages of the history of the science is facilitated by an appeal to a significant documentary base: manuscripts, audio recordings, photographs. Generalization of information and critical analysis of the sources make it possible to clarify the events of the past and give a correct assessment of the results of the activities of scientists. One of the promising historical and textual methods used in several articles is comparison of notations and phonograms of the 19th — early 20th centuries with transcripts of audio recordings made in the 1970s and 80s and later. The conclusions made on this basis concern not only approaches to fixing materials, but also the dynamics of changes in song traditions. Arealogical surveys based on the results of field work of many generations of researchers are in great demand. Such studies open the prospect of further generalization and historical assessment. No less relevant for ethnomusicology are problems of using musical folklore in the works of composers, as well as the practice of modern performers to use the methods of playing music developed in the oral tradition.
“Good Man and Not a Plotter; Free and Able to Travel”: Three Episodes from the Biography of Eugene W. Hippius
Authors: Подрезова С.В.
Published: June 2024

В статье раскрываются неизвестные страницы научной биографии одного из ведущих отечественных этномузыковедов — Евгения Владимировича Гиппиуса. В научный оборот вводятся архивные документы, охватывающие период 1926–1929 гг. и позволяющие по-новому представить начало его пути как собирателя, архивиста и исследователя. Данные полевого дневника Гиппиуса дают возможность более точно атрибутировать фонографические записи, обозначить методы и особенности собирательской работы в Заонежье, оценить его вклад в камеральную обработку фонозаписей. «Программа фонографических записей» (1926) отражает научный подход Е. В. Гиппиуса и З. В. Эвальд к жанровой классификации заонежского фольклора. Записки и письмо к С. И. Бернштейну, заведующему Центральным Фонограммархивом Государственного института истории искусств, свидетельствуют об активном участии Гиппиуса в обсуждении перспектив развития этого подразделения. Автор приходит к выводу, что в конце 1920-х гг. полевая и исследовательская работа Государственного института истории искусств и Ленинградской государственной консерватории была тесно взаимосвязана и проходила в рамках нового научного направления — сравнительного музыкознания. Важная роль в этом принадлежала Гиппиусу.

The article reveals previously unknown pages of the biography of one of the leading Russian ethnomusicologists — Eugene W. Hippius. Archival documents covering the period 1926–1929 introduced into scientific circulation, allow us to develop a new approach to to looking at the first steps this inspiring collector, archivist and researcher. Hippius recorded in his field diary the main events and meetings, reflecting some details of the everyday life and phonographic capacities. The second part of his field diary reports on the initial inventory of wax cylinders, which makes it possible to restore the lost part of folklore sound recordings. The “Program of Phonographic Recordings” (1926) reflects the scientific approach of Eugene Hippius and Zinaida Ewald to the genre classification of Zaonezhye’s folklore. Notes and a letter to S. I. Bernstein, head of the Central Phonogram Archive of the State Institute of Art History, emphasizes Hippius’ active participation in discussing the prospects for the development of this department. The author comes to the conclusion that the field and re search work of the State Institute of Art History and the Leningrad State Conservatory in the late 1920s were closely interconnected and occurred within the framework of a new scientific direction — comparative musicology.
Pinega Tradition of Singing Lyrical Songs Recorded in 1927–1930: Features of Voice Performance and Musical Texture
Authors: Якубовская Е.И.
Published: June 2024

Многоголосие в народных песенных традициях Русского Севера представляет одно из сложнейших художественных явлений русской национальной культуры. Вместе с тем оно недостаточно изучено, поскольку большинство ранних записей малодоступны для непосредственного слухового анализа. Опубликованные нотировки отражают лишь небольшую часть имеющихся звукозаписей. В статье рассматриваются особенности голосоведения и фактуры классических «протяжных» лирических песен в устной традиции Русского Севера. Материалом исследования послужили полевые фонографические записи Е. В. Гиппиуса и З. В. Эвальд, сделанные ими в 1927 и 1930 гг. в деревнях Пинежского района Архангельской области. В ходе анализа привлекаются фонограммы, выполненные в тех же деревнях в 1990-е гг. при участии автора статьи. В работе уделяется особое внимание двухрегистровому пению «тонки´ми» и «толсты´ми» голосами, а также закономерностям мужского и женского исполнительства в смешанных певческих ансамблях. Авторские нотации песен публикуются впервые.

The polyphony of the Russian North represents one of the most complex artistic phenomena of Russian national culture. At the same time, it has not been sufficiently studied, since most early recordings are poorly accessible for direct auditory analysis. The published scores reflect only a small portion of the available sound recordings. The article examines the features of vocal performance and musical texture of classical “lingering” lyrical songs in the oral tradition of the Russian North. The research material was the field phonographic recordings of Eugene W. Hippius and Zinaida V. Ewald, made by them in 1927 and 1930 in the villages of the Pinezhsky district of the Arkhangelsk region. The analysis involves phono grams made in the same villages in the 1990s, with participation of the author of the article. The study examines such a feature of the musical texture as two-register singing with “thin” and “thick” voices, male and female performance in mixed singing ensembles. The author,s notations of the songs are published for the first time.
Folk Ural Melodies in Sergei Prokofiev’s Ballet “The Tale of the Stone Flower”
Authors: Долгова Д.К.
Published: June 2024

Последний балет С. С. Прокофьева «Сказ о каменном цветке» отражает итог работы композитора в данном жанре. Связи с народной культурой в балете проявляются на различных уровнях — сюжетном, музыкально-тематическом, драматургическом. В настоящей статье установлены народно-песенные источники музыкального тематизма балета, представленные в архивах и публикациях, приведены нотации. Прокофьев включает в партитуру напевы уральского фольклора, что указывает на понимание им своеобразия локальных традиций. Уточнен жанровый состав используемых образцов: свадебное причитание, лирические и хороводные песни. Часть заимствованного Прокофьевым материала ранее послужила основой его «Обработок русских народных песен для голоса с фортепиано» оp. 104, что позволяет расширить представление о принципах работы композитора с фольклорными источниками в  различных жанровых направлениях. Обнаружено, что большинство народных мелодий служит основой тем сквозного значения. Специфика их функционирования в балетной музыке заключается в творческом переосмыслении Прокофьевым метроритмических, интонационных и композиционных параметров напевов.

The last ballet The Tale of the Stone Flower displays the outcome of the development of Prokofiev’s work in this genre. Connections with the folk culture in the ballet manifest themselves at various levels — those of the plot, music themes and dramaturgy. This article establishes folk song sources of the music themes of the ballet presented in archives and publications, and provides appropriate notations. Prokofiev includes samples of the Ural folklore, which indicates his understanding of uniqueness of the local traditions. The genre composition of the samples used has been clarified, namely wedding lamentation, lyrical and round dance songs. A part of the borrowed material was previously used by the author of The Tale of the Stone Flower in his Arrangements of Russian folk songs for voice and Piano, op. 104, which makes it possible to expand understanding of the principles of composer’s interaction with folklore source in various music genres. Most tunes were found to play the role of through themes. The specifics of folk songs functioning in the ballet lies in Prokofiev’s creative reinterpretation of the rhythmic, intonation and compositional parameters of the melodies.
Science of Folk Musical Culture: History and Methodology
Authors: Морозов Д.В.
Published: June 2024

В статье рассматриваются вопросы становления и современного развития отечественных научных направлений: этномузыкологии, этноорганологии и этнохореологии. Исследование базируется на оценке содержания более 500 диссертаций, защищенных с 1970 по 2020 г., в которых раскрываются проблемы изучения народных песен и традиционной музыкальной культуры в целом, а также научных трудов в области музыкальной компаративистики, ареалогии, структурной и исторической типологии, эволюционизма и текстологии фольклора, практической этномузыкологии. Систематизация этномузыкологических методов проведена с использованием принципов классификации, разработанных З. И. Комаровой в лингвистике. Этномузыкология изучается на парадигмальном уровне как наука о народной музыкальной культуре и на дисциплинарном уровне как наука о формах народной музыки и их функционировании.

The article discusses formation and modern development of domestic scientific directions: ethnomusicology, ethnoorganology and ethnochoreology. The study is based on an assessment of the content of more than 500 dissertations defended from 1970 to 2020, which reveal the problems of studying folk songs and traditional musical culture in general, as well as scientific works in the field of musical comparative studies, arealogy, structural and historical typology, evolutionism and textual criticism of folklore, practical ethnomusicology. The systematization of ethnomusicological methods was carried out using the principles of classification developed by Zoya I. Komarova in linguistics. Ethnomusicology is studied at the paradigmatic level as the science of folk musical culture and at the disciplinary level as the science of folk music forms and their functioning.
Field Diary of the Zaonezhye Expedition and Letter to Sergey I. Bernstein
Authors: Гиппиус Е.В. , Подрезова С.В.
Published: June 2024

Впервые публикуются документы, отразившие историю появления двух ранних коллекций звукозаписей, хранящихся в Фонограммархиве Института русской литературы (Пушкинского Дома) РАН (ИРЛИ): №1 (экспедиция ГИИИ в Заонежье, 1926 г.) и №38 (экспедиция Ленинградской консерватории в Узбекистан, 1928 г.). Публикуемые источники имеют большую научную и документальную ценность как свидетельство становления отечественного этномузыкознания и начала полевой звукозаписи Государственного института истории искусств (ГИИИ) и Ленинградской государственной консерватории (ЛГК). В полевом дневнике, который Гиппиус вел в своей первой фольклорной экспедиции в Заонежье в 1926 г., фиксировались основные события и встречи, отражались некоторые бытовые детали и технические характеристики записи. Во второй части дневника сохранилась первоначальная опись фоноваликов, благодаря которой можно судить об утраченных образцах (из 67 фоноваликов до нашего времени дошло лишь 41). Сопоставление данных дневника Е. В. Гиппиуса с уже известными документами позволит более точно атрибутировать фонографические и слуховые записи. Письмо Гиппиуса к заведующему Центральным Фонограммархивом ГИИИ — лингвисту С. И. Бернштейну содержит новые сведения об особенностях организации полевой и кабинетной работы фольклористов ГИИИ и ЛГК и о степени участия в ней Е. В. Гиппиуса.

The article presents documents that reflect the history of the appearance of two early collections of the Pushkin House Phonogram Archive: collection No. 1 (expedition of the State Institute of Art History in Zaonezhye, 1926) and collection No. 38 (expedition of the Leningrad Conservatory to Uzbekistan, 1928): field diary of Eugene W. Hippius, “Program of phonographic recordings made in the Zaonezhye expedition”, which the young scientist kept on his first folklore expedition, and which was demonstrated at a meeting of the Department of Music Theory and History Council (September 20, 1926); and a letter from Eugene W. Hippius to the head of the Central Phonogram Archive of the State Institute of Art History — linguist Sergei I. Bernstein. The published sources have great scientific and documentary value as evidence of the early period of Russian ethnomusicology and the beginning of field work at the State Institute of Art History and the Leningrad Conservatory. Comparison of the data from the diary of Eugene W. Hippius with field notes of the participants of the Zaonezhye expedition will make it possible to more accurately attribute phonographic and auditory recordings. Hippius’s letter to Bernstein contains unique information about peculiarities of organization of field and cabinet work of folklorists of the State Institute of Art and Culture and the Leningrad Conservatory and the degree of participation of Eugene W. Hippius therein.
Glycosylation-Enhanced Luminescence of Nonaromatic Amino Acids
Authors: Zhang Qiang , Zhao Zihao , Yang Guangxin , Li Anze , Cui Yijing , Cai Yusong , Yin Zhuojie , Tan Yuntian , Zhou Chenyang , Peng Qian , Yuan Wang Zhang
Published: June 2024

Nonaromatic amino acids with intrinsic photoluminescence (PL) have drawn growing attention due to their crucial role in the luminescence of natural proteins. Nevertheless, the faint luminescence significantly constrains the mechanism exploration of biomolecules as well as their practical applications. We here report a serendipitous finding of synergetic PL enhancement by coupling both weakly emissive nonaromatic amino acids and sugars via glycosidic bonds. Namely, glycosylation drastically boosted the quantum yields of nonaromatic amino acids from 0.3% to as high as 9.2%, accompanied by the emergence of pro-nounced persistent room temperature phosphorescence (p-RTP). This synergistic PL enhancement arises from the ingenious integration of the electron-rich oxygen clusters present in sugar with the charge separation characteristics of amino acids. Driven by amino acids, ample electrons supplied by the sugar rings are directionally induced to promote electron delocaliza-tion, as well as subsequently enhanced absorption, resulting in a more efficient excitation process. Furthermore, the ultrafast femtosecond to nanosecond transient absorption (fs-TA, ns-TA) spectroscopy and theoretical calculations further reveal the importance of hybridization of the locally excited (LE) and the charge transfer (CT) states for PL enhancement and p-RTP features. These results not only provide a universal strategy for constructing efficient nonconventional luminophores but also shed new light on the underlying mechanism of biological autofluorescence.
Thermodynamically Consistent Atomic Radii of Main Group Elements
Authors: Alibakhshi Amin , Schäfer Lars V.
Published: June 2024

Atomic radius is a fundamentally important quantity shaping multiple properties of atoms, molecules, and materials. Due to its fundamental importance, precise quantification and interpretation of atomic radii has been the subject of numerous studies for more than a century. It has resulted in a broad variety of estimations of atomic radii which so far have not been amenable to extensive verification by experiment. The present study follows our recent work demonstrating that electron iso-density surfaces, contoured at a certain cut-off density, accurately represent molecular surfaces determined via thermodynamic phase change data. Here we provide thermodynamically consistent estimates of atomic radii for the main group elements.
Organosilicon Precursors for Efficient Aromatic Copper-Mediated Radiocyanation
Authors: Wright Jay , Ma Richard , McCarthy Casey , Kaup Gina , George Emma , Priest Joshua Duncan , Webb E. William , Cheng Kevin , Bowden Gregory , Brooks Allen , Shao Xia , Sanford Melanie , Scott Peter
Published: June 2024

Copper-mediated radiolabelling has revolutionised how (hetero)aromatic imaging agents are prepared for positron emission tomography (PET). Despite advancements, this radiochemistry fails to address critical stability, reactivity, and toxicity concerns encountered in many labelling systems, which are paramount for safely and reproducibly generating patient radiomedicines. To overcome these limitations, a copper-mediated 11C-cyanation reaction is presented that leverages heptamethyltrisiloxanes as (hetero)aryl nucleophiles. Rapid ipso-radiocyanation occurs in conversions that surpass related precursors while offering stability and toxicity advantages. Preliminary mechanistic data suggests that a difluoro(methyl)aryl silane may be generated prior to transmetallation. Multiple bioactive scaffolds relevant to (pre)clinical PET were labelled to showcase the broader significance of this protocol, including an automated radiosynthesis of a -opioid receptor antagonist currently under clinical investigation. Overall, adopting aryl silane precursors will augment radiochemical space and support the production of PET nuclear medicines.
Nanowire Morphology Control in Sb Metal-derived Antimony Selenide Photocathodes for Solar Water Splitting
Authors: Wang Zhenbin , Gan Yongping , Service Erin , Adams Pardis , Moehl Thomas , Niu Wenzhe , Tilley David
Published: June 2024

We report a facile method to enhance the photoelectrochemical (PEC) performance of Sb2Se3 photocathodes by controlling the growth of bilayer Sb2Se3 consisting of vertically oriented nanorods on a compact Sb2Se3 layer. Sb2Se3 thin films with controllable nanorod diameters were achieved by manipulating the substrate temperature during metallic Sb thin film deposition. The lower temperature-derived Sb2Se3 photocathode, with a larger nanorod diameter (202 ± 48 nm), demonstrated a photocurrent density of -15.2 mA cm−2 at 0 VRHE and an onset potential of 0.21 VRHE. In contrast, the higher temperature-derived Sb2Se3 photocathode, with a smaller nanorod diameter (124 ± 28 nm), exhibited an improved photocurrent density of -22.1 mA cm−2 at 0 VRHE and an onset potential of 0.31 VRHE. The enhanced PEC performance is attributed to reduced charge recombination facilitated by a shorter charge transport path in the [hk0] direction. This study highlights the significance of morphology control in optimizing Sb2Se3 photocathodes, providing insights for future material and device design.
Methane Adsorption Isotherms for MOF Structures from the PrISMa Database
Authors: Moubarak Elias , Garcia Susana , Smit Berend
Published: June 2024

This work reports methane adsorption isotherms in over 1000 MOF structures
Interrogating Steady-State Multi-electron and Multi-step Reactions Mediated by an Electrocatalytic Heterogeneous Film
Authors: Chen Yu-Wei , Wang Vincent
Published: June 2024

The development of new types of heterogeneous catalysts for fuel-forming electrochemical reactions has been a subject of research focus over the past decade. Despite recent huge progress in preparations of electrocatalytic materials, such as metal organic framework (MOF) and redox polymer, understanding the underlying microscopic mechanisms at play and the key rate-limiting step is still poor due to a lack of electrochemical analysis tools. Here, complete electrokinetic models for multi-electron redox reactions for heterogeneous electrocatalysis, including a monolayer (2D) and porous 3D film, are developed to comprehensively interrogate all relevant kinetic parameters, charge transport, substrate diffusion and catalysis. Therefore, the effects of these parameters on the resulting voltammograms can be analyzed and then the characteristic properties of electrocatalytic voltammograms are identified. In addition, the foot of the wave analysis, widely used to evaluate the catalytic performance of molecular catalysts in the homogeneous system, is also applied and found to be a useful tool to characterize the kinetic mechanism of the chemical steps. Based on these electrochemical methods and analysis, the MOF systems are evaluated to address the discrepancy among these kinetic parameters reported in the literature. Further design principles for catalytic MOF films and their theoretical performance are provided. Overall, these electrochemical methods presented here provide useful and feasible tools to benchmark heterogeneous electrocatalysts and characterize the key step that limits the electrocatalytic performance of MOFs and other heterogeneous systems.
Docking-based Virtual Screening for the Discovery of RNA-targeting Molecules: Identification of Selective Riboswitch Binding Ligands
Authors: Stille Julia , Takyi Nathania , Ayon Omma , Rivera Maira , Satkunarajah Thershan , Pottel Joshua , Mittermaier Anthony , McKeague Maureen , Moitessier Nicolas
Published: June 2024

We present herein one of the very first applications of molecular docking towards the discovery of novel RNA-targeting molecules. Our in-house docking program FITTED was used to perform independ-ent virtual screening campaigns against the TPP, SAM, and FMN riboswitches. Based on the predicted docking scores and poses, between 14 and 20 compounds were selected from commercial libraries and purchased for experimental evaluation of binding to their respective riboswitches by surface plasmon resonance. Promisingly, two compounds displayed highly specific and dose-dependent binding to the TPP riboswitch and FMN riboswitch, with experimentally-determined KDs of 170 μM and 220 μM, re-spectively. This work highlights the promise of modifying and applying docking programs for the dis-covery of nucleic acid- targeting molecules.
A Comparative Study Between Pemetrexed and Taxanes as First Line Treatment of Metastatic Lung Adenocarcinoma
Authors:   Oncology Teaching Hospital, Baghdad, Iraq, Qahtan Al-Salihi Sarmad , Sabieh Al Zubaidi Azhar
Published: June 2024

Background: Adenocarcinoma of the lung is the most common type of lung cancer. Platinum agents in combination with other chemotherapy are currently the cornerstone for chemotherapy of advanced cases with metastasis. Objective: To compare the response rate of pemetrexed doublets versus taxanes doublets in patients with metastatic lung adenocarcinoma. Patients and Methods: This a prospective study that included 60 patients with pulmonary adenocarcinoma. Those patients received a platinum based doublet chemotherapy with additional treatment protocol; combined with either pemetrexed or taxanes (paclitaxel or docetaxel) with 30 patients in each arm. Tumor size, response rate and side effects of chemotherapy were evaluated in both arms. Results: The median reduction in tumor size in pemetrexed and taxan arms were 4.72 cm2 and 6.53 cm2 respectively. Nausea, fatigue, constipation and anorexia were more common in pemetrexed arm, while leukopenia, arthralgia and peripheral neuropathy were more common in taxan arm. Conclusion: Serious side effects such as leukopenia, and peripheral neuropathy were more common in taxan than pemetrexed arm. Pemetrexed is preferable to use as a fist line treatment for patients with metastatic adenocarcinoma of the lung. Keywords: Adenocarcinoma, Pemetrexed, Taxanes, metastatic lung cancer.
On commercial construction activity's long and variable lags
Authors: Glancy David , Kurtzman Robert , Loewenstein Lara P.
Published: June 2024

We use microdata on the phases of commercial construction projects to document three facts regarding time-to-plan lags: (1) plan times are long - about 1.5 years - and highly variable, (2) roughly 40 percent of projects are abandoned in planning, and (3) property price appreciation reduces the likelihood of abandonment. We construct a model with endogenous planning starts and abandonment that matches these facts. The model has the testable implication that supply is more elastic when there are more "shovel ready" projects available to advance to construction. We use local projections to validate that this prediction holds in the cross-section for US cities.
Insecticide applications with trunk injection method for reducing the damage level of Leptoglossus occidentalis (Heidemann, 1910) in stone pine stands
Authors: Sarikaya O. , Parlak S. , Yildiz Y. , T. Gencal  , I.M. Ozcankaya  , F. Selek  , O. Acici  , H. Can
Published: June 2024

Leptoglossus occidentalis was first detected in Türkiye in 2009. The pest's damage to stone pine trees and its effects on seeds cause economic losses. In recent years, observations and predictions show that there is a significant threat not only to stone pine but also to other coniferous forests throughout country. In this study, pesticides were applied by trunk injection method in the experiment areas taken in stone pine stands of Bergama - Kozak region. In the systemic application carried out in 2020 and 2021, the Arborjet system was used and the insecticide with the active ingredient Azadirachtin (0.3 g/Lt) was used as an organic insecticide, as well as pesticide with the active ingredient Imidacloprid (200 g/Lt). In 2020, the highest seed filling rate was achieved after systemic Imidacloprid insecticide application with the Arborjet system. As a result of this application, the full seed rate reached 70.7% in Asagicuma, while this rate was 63.6% in the Karaveliler. The seed occupancy rate obtained from control trees in the Asagicuma was 37.96% and this rate reached 70.7% after systemic Imidacloprid application in the same field. Similarly, in the studies carried out in Asagicuma and Yukaribey experiment sites in 2021, only 35% of the seeds were filled in the cones taken from control trees, while the occupancy rate in the cones without insecticide application in the Yukaribey was determined to be 32.76%. In both trial sites, the highest seed fill rate was achieved after systemic Imidacloprid insecticide application with the Arborjet system. As a result of this application, the filled seed rate reached 67.89% in the Asagicuma and 69.86% in Yukaribey experiment sites.
Effect of phosphate nature on the inhibitory capability of phosphate compositions
Authors: A.B. Niyazbekova  , T.A. Shakirov  , L.I. Baytlesova  , N.M. Zhunusbekova  , Niyazbaeva A.I. , G.M. Gubaidullina
Published: June 2024

Corrosion inhibitors find ubiquitous application across diverse sectors to formulate robust coatings and chemical compounds. Serving as pivotal additives in compositions, they play a vital role in crafting coatings for circulating water systems, water supply networks, oil refining, petrochemical industries, and power plants. Incorporation extends to fuels, oils, lubricants, and construction materials. In industries oxidation inhibitors is particularly high as chemical, electrochemical, petrochemical, and gas, as well as in water supply networks and circulating water systems. The utilization of inhibitors obviates the necessity for treating metal surfaces with protective enamels and mastics. Effectively preventing oxidation involves the introduction of chemical contributions into aggressive ecology, thereby neutralizing or retarding the oxidation processes. This article explores the anti-oxidation properties of inhibitors in compositions related to St-3 steel. The study includes factors such as the pH of the medium, the nature and concentration of phosphate in compositions simulating reservoir water under stationary and aerated conditions. Investigation methods as potentiometry and photocolorimetry used in research. Experimental data, quantitative parameters of the oxidation process, oxidation rate, and degree of protection, depth index, and stability of the film formed were determined. These indicators were assessed on the oxidation resistance scale relative to steel. Analysis of the data shows that out of 63 compositions, seven systems demonstrate the most significant protective effects, with five containing sodium orthophosphate and two containing sodium hydroorthophosphate. The effective, surrounding friendly and cost-effective steel oxidation inhibitors using materials from Kazakhstan will contribute to the development of industry,
Aspects of DNA interaction with the natural heterocyclic compounds
Authors: Kamalabadi M. , Chehardoli Gh.
Published: June 2024

Cancer is now one of the major challenges in the medical world. An unhealthy lifestyle, and abuse or inappropriate use of drugs stimulate this disease. The drug resistance and imperfections of drugs used in cancer therapy have enforced the development of new drugs with therapeutic potential. Despite the introduction of synthetic drugs, the discovery of new drugs with natural origin has increasing attention in the treatment of diseases, recently. As natural compounds show a considerable diversity of chemical structures, they are liable for diverse mechanisms of action and interaction with target molecules. Heterocyclic natural compounds are a substantial part of natural compounds with excellent properties. These compounds possess various interaction modes with DNA. This review focus on the heterocyclic natural compounds with therapeutic potential and their binding mode with DNA.
The effects of core training on endurance in different trunk movements
Authors: Dudagoitia Barrio Ekaitz , Hernandez-García Raquel , Ramírez-Campillo Rodrigo , García de Alcaraz Antonio
Published: June 2024

Core muscle endurance involves the trunk muscles’ capability to maintain a particular position for as much time as possible. It is essential to know how specific training aimed at this area affects endurance of different trunk movements performance and to what extent. The objective was to assess the effects of trunk training on different core muscle endurance measurements in flexion, extension, and right and left lateral flexion. A literature search was performed using different databases. The studies included: (a) cohorts of healthy people or subjects with chronic low back pain; (b) a core training intervention; (c) pre-post intervention parameters of interest; (d) a minimum of 4 out of 10 on the PEDro scale, and (e) randomised controlled trials. A random-effects model for meta-analyses was used. Fifteen studies were selected for the systematic review and 11 for the meta-analysis, comprising 1,213 participants. Compared to the control condition, core training induced a moderate effect on trunk flexion endurance (ES = 0.67), right-lateral trunk flexion endurance (ES = 0.77), left-lateral trunk flexion endurance (ES = 0.94), and a small effect on trunk extension endurance (ES = 0.49). To back up the results presented in this study, more research into the effects of trunk training on core muscle endurance is needed to confirm these results significantly. Core training improves core muscle endurance in four trunk movements. Core training is more effective in participants with pre-intervention poor results.
Utilização de ferramentas da Qualidade em laboratórios de pesquisa – um relato de caso
Authors: Medeiros Suelen Carneiro de , Dabés Clarice Gomes e Sousa , Maia Geiciane Silva , Fernandes Carla Freire Celedonio , Marinho Anna Carolina Machado
Published: June 2024

Objetivo: O objetivo deste estudo é discutir a aplicação do Quality by Design (QbD) e a utilização do Diagrama de Ishikawa como ferramentas na tomada de decisões em experimentos envolvendo pesquisa e desenvolvimento de biomoléculas.
 Referencial Teórico: É sabido que ferramentas de produtividade podem garantir a qualidade do produto, como a abordagem Quality by Design (QbD). Pensando como produto o resultado de um experimento ou processo, estas ferramentas também podem ser utilizadas nesse contexto, garantindo que os resultados possam ter confiabilidade e reprodutibilidade.
Método: O setor de Qualidade da instituição propôs a realização de treinamento técnico abordando QbD e outra ferramenta da qualidade, após observações em campo para definição de tema, sendo realizadas em instituição de pesquisa pública brasileira, que trabalham com o desenvolvimento de bioprodutos.
Resultados e Discussão: O treinamento foi síncrono e remoto, sendo possível a representação de outros estados. A maioria dos participantes não conheciam a abordagem QbD e o Diagrama de Ishikawa. A partir das discussões, foi elaborado um plano de ação cujo foco foi solucionar o problema do armazenamento das biomoléculas.
 Implicações da Pesquisa: A utilização dessas ferramentas pode melhorar a confiabilidade e reprodutibilidade dos dados em pesquisas científicas, bem como diminuir desperdícios de material e tempo dos processos.
 Originalidade/Valor: Este estudo promove a discussão sobre como a abordagem QbD, amplamente utilizada na indústria, auxiliaria na detecção de pontos de controle e análise de risco para serem incorporados no processo de obtenção das biomoléculas e em protocolos analíticos de experimentação, dentro dos laboratórios de pesquisa.