bluuebunny/crossref_metadata_2025 huggingface dataset:
Transformação econômica na China: o papel do crédito bancário
Authors: Cubero Marilia Ceci , Mendonça Ana Rosa Ribeiro de
Published: August 2024

Resumo O crescimento econômico da China representa um dos fenômenos mais notáveis da economia mundial contemporânea. O sistema de crédito bancário desempenhou um papel fundamental, atuando como força de sustentação para o crescimento e de orientação para a transformação da economia. Isso posto, o presente artigo pretende tratar algumas das características do sistema de crédito bancário na China, buscando destacar estratégias e iniciativas, assim como políticas e regras que delas derivaram – e que têm direcionado o crédito. Deste modo, está organizado em 5 seções, incluindo esta introdução e considerações finais. Na segunda seção, uma caracterização do sistema de crédito bancário em quatro fases é apresentada, com destaque, em cada uma delas, a elementos de política, atores e segmentos privilegiados, assim como transformações. Na seção 3, uma descrição do comportamento do crédito é realizada, mostrando o movimento do crédito em geral e do crédito para empresas e famílias. A seção 4 trata do processo de reconfiguração do crédito e procura apontar as mudanças nos alvos das concessões a partir do estabelecimento do conceito de new normal. Por fim, considerações finais são tecidas.
FALA REPRESADA E AMOR TRANSBORDANTE: AMOR E AMIZADE EM MACHADO DE ASSIS
Authors: SILVA ANDRÉ LUIZ BARROS DA
Published: August 2024

Resumo: Investigamos como Machado de Assis, no conto "Pílades e Orestes", propõe um modo singular de figurar a fala represada como signo ou sintoma da amizade e do amor, tanto no âmbito do personagem como no da forma narrativa. Tentamos mostrar como a postura do personagem Quintanilha pode ser entendida como inversão de papéis sexuais e familiares e como figuração da neurose histérica, em chave psicanalítica. Para tanto, comparamos o conto não apenas com os dois últimos romances de Machado, mas também com tragédias gregas que figuram o mito, além de dois contos da França do século XVIII, de Diderot e de Saint-Lambert.
“Love Is What Love Does” - Stories of Representation and Belonging in Hair Love, by Matthew A. Cherry
Authors: Magalhães Milena , Alencar Rosana Nunes
Published: August 2024

ABSTRACT This text reflects on the representativeness of the kinky hair (or afro-textured hair) as an element of racial belonging in children’s literature, based on the book Hair Love, by the African American director, producer, and writer Matthew A. Cherry. To do so, it investigates how the illustrations by Vashti Harrison, also an African American, align with the text to express a vision of black individuals and of their family without usual stereotypes. Drawing on bell hooks’ notion of love, this analysis undertakes a reading that runs through both thematic and structural aspects of the narrative, hypothesizing that the book, without making direct allusions, serves as a counter-discourse to the racism that originated during slavery, the effects of which can still be felt today. From a theoretical perspective, in addition to hooks, this reading is grounded on a conceptual framework guided by the studies of Eliane Debus, Grada Kilomba and Nilma Lina Gomes.
O gênero entrevista sociolinguística e suas dimensões cronotópicas
Authors: Oliveira Érica Marciano de
Published: August 2024

RESUMO A entrevista sociolinguística tem sido estudada em diferentes aspectos, por pesquisadores de variadas áreas. Este texto busca ampliar a perspectiva de análise de entrevistas sociolinguísticas, em uma abordagem interdisciplinar, articulando noções do campo discursivo com outras do campo antropológico e do campo sociolinguístico. Os objetivos específicos deste trabalho são: (i) articular os conceitos de cronotopo, performance de linguagem e atos de postura (stance) para o estudo das dimensões cronotópicas na entrevista sociolinguística; (ii) expor e descrever essas dimensões e seus aspectos indexicais; e (iii) propor algumas estratégias metodológicas que podem ser adotadas para o mapeamento das dimensões cronotópicas nas entrevistas sociolinguísticas. Como resultado, exponho algumas contribuições dessa articulação conceitual e da estratégia metodológica utilizada, atentando-se também para a investigação de dados emergentes dessa prática discursiva.
Etnologia indígena na Alemanha: do legado bastiano até o cenário atual
Authors: Schröder Peter
Published: August 2024

Resumo O objetivo deste artigo é apresentar e explicar a conceituação, o surgimento e as transformações da etnologia indígena no contexto de um país que nunca teve colônias ultramarinas nas Américas. Na etnologia alemã, que pode ser considerada uma antropologia ex-hegemônica, a etnologia indígena se manifesta tradicionalmente em vários americanismos com especializações regionalistas. O argumento principal é de que suas transformações históricas só se tornam mais inteligíveis quando conectadas com o contexto mais abrangente da disciplina na Alemanha desde o final do século XIX. No decorrer de quase um século e meio, podem ser constatadas transformações profundas nas relações com as antropologias latino-americanas: inicialmente, uma posição hegemônica (até a década de 1930), depois, um declínio considerável até uma relativa invisibilidade, mas, a partir da década de 1970, uma crescente influência temática e teórica latino-americana que permite diagnosticar uma inversão nas relações tradicionalmente assimétricas entre uma antropologia europeia e as diversas antropologias latino-americanas.
Dos protestos, escrachos e ocupações à Vara Agrária: o direito de propriedade nos conflitos por terra em Alagoas
Authors: Castro Ana Carolina de Sousa , Lima Weldja Marques da Silva
Published: August 2024

Resumo O presente artigo objetiva analisar as disputas em torno da categorização do direito de propriedade privada em Alagoas a partir dos conflitos agrários julgados na Vara Agrária do estado. Criada em 2009, a Vara Agrária de Alagoas é destinada exclusivamente para a conciliação e o julgamento de conflitos agrários no estado. Nela, não raro, as manifestações dos movimentos sem terra são enquadradas a partir da ideia de ameaça e dano à propriedade e ao direito de propriedade, em ações de reintegração de posse ajuizadas por proprietários de terra. Por outro lado, os movimentos sociais sem terra têm reivindicado, cada vez mais, espaços para os seus próprios enquadramentos sobre direito de propriedade e uso da terra, especialmente a partir do argumento da função social da propriedade. Para a realização do estudo, utilizamos a teoria da mobilização do direito (legal mobilization theory), a fim de investigar a estrutura de oportunidades legais e os recursos disponíveis, além de elementos dos processos de enquadramento (framing process). A teoria da mobilização do direito nos auxilia na compreensão da relação entre movimentos sociais, direito e Poder Judiciário. O artigo está ancorado na análise de 241 processos judiciais que tramitaram na Vara Agrária durante o período de 2009 a 2014, bem como entrevistas com magistrados e integrantes dos movimentos sociais sem terra em Alagoas. A pesquisa abrangeu a atuação de três magistrados titulares. A hipótese principal do artigo é que a vara se transforma em um espaço de tensões, nos quais os diferentes enquadramentos estão em colisão na busca por influenciar a decisão judicial, ao mesmo tempo em que as decisões judiciais impactam a dinâmica dos conflitos agrários em Alagoas e a própria leitura e entendimento dos movimentos sociais sobre a propriedade. Acrescenta-se como hipótese a consolidação de uma disputa em torno de argumentos jurídicos sobre a questão da posse e da propriedade, de um lado, e, do outro, o direito à manifestação e a função social da propriedade; para que seus argumentos sejam juridicamente considerados, os movimentos sociais precisam traduzir os enquadramentos próprios da mobilização de rua para um enquadramento jurídico, o que é feito por meio das categorias da função social da propriedade. Tais enquadramentos tensionam os limites do direito de propriedade, ao justificar em uma linguagem jurídica o que, a princípio, é enquadrado como dano ou violência.
Speech self-perception algorithm objective analysis with elderly hearing aids users
Authors: Silva Renata da , Martinelli Maria Cecilia
Published: August 2024

ABSTRACT Purpose To analyze, by electroacoustic verification at 65 dB SPL, the Speech Intelligibility Index (SII), with the speech self-perception algorithm activated and deactivated in elderly hearing aid users. Methods This is a cross-sectional observational study. The participants were 40 older adults with mild to severe bilateral symmetrical sensorineural hearing loss, aged between 60 and 80 years, who attended a hearing center, users of Rexton receiver-in-the-canal (RIC) devices, My Core platform with speech Self-perception algorithm. After an audiological evaluation, the hearing aids were programmed using the NAL/NL2 prescriptive method and fine-tuned according to individual needs. The speech self-perception algorithm was calibrated and after performing the electroacoustic verification, the Speech Intelligibility Index was quantified. Electroacoustic verification was performed with and without the self-perception of speech algorithm enabled. Statistical analysis was performed using the SPSS Statistics software, version 28.0. The statistical significance value was equal to 5% (p ≤ 0.05). Results In the right ear, without activation of the algorithm, the average SII was 58.9% (±14.7) and with activation, 57.85% (±14.8). In the left ear, without activation of the algorithm, the SSI was 63.1% (±15.13) and with activation, 61.9% (±15.2). There was statistical significance between the SII obtained with the algorithm on and off (p<0.001). In both ears, with the self-perception activated algorithm activated, the mean SII was lower than without. Conclusion There is a reduction in SII with the self-perception of speech algorithm activated in strong mode.
Os fazeres da terapia ocupacional no campo da saúde mental infantojuvenil
Authors: Táparo Flávia Arantes , Constantinidis Teresinha Cid , Cid Maria Fernanda Barboza
Published: August 2024

Resumo Introdução Embora, ao longo da história, a terapia ocupacional acompanhe ativamente o desenvolvimento do campo da saúde mental infantojuvenil, há pouca produção sobre os elementos que caracterizam o núcleo da profissão neste campo, destacando-se a importância de pesquisas que avancem nesta direção. Objetivos Identificar a perspectiva de terapeutas ocupacionais envolvidos na atenção psicossocial de crianças e adolescentes sobre o núcleo profissional da terapia ocupacional no campo da saúde mental infantojuvenil, além de analisar como os demais profissionais envolvidos na atenção psicossocial de crianças e adolescentes descrevem a prática de terapeutas ocupacionais neste campo. Método Estudo com abordagem qualiquantitativa, desenvolvido em duas fases. A primeira contou com a participação de 107 profissionais atuantes no campo da saúde mental de crianças e adolescentes, que responderam um questionário online. Na segunda fase, participaram 32 profissionais, que compuseram quatro grupos focais virtuais. Para análise dos dados de ambas as fases, foi utilizado o software Iramuteq®. Resultados Foram identificados como fazeres característicos da terapia ocupacional no campo da saúde mental infantojuvenil: o enfoque nas ocupações, atividades de vida diária, rotinas e cotidiano dos indivíduos; a perspectiva integral sobre os sujeitos, a tessitura de redes e o fomento à intersetorialidade; a atuação frente ao sofrimento psíquico intenso e o manejo das situações de crise; e a atuação nos casos mais graves e complexos. Conclusão O estudo demonstra as características dos fazeres da terapia ocupacional no campo da saúde mental infantojuvenil, destacando a importância deste núcleo profissional para a construção coletiva do cuidado no referido campo.
Exploring the behavior and quality control of steel fiber reinforced concrete through 3-point bending test and Montevideo test
Authors: Bahniuk Gabriela Mazureki Campos , Pieralisi Ricardo , Machado Roberto Dalledone
Published: August 2024

Abstract Residual tensile strength plays a critical role in the design of steel fiber-reinforced concrete (SFRC) elements. It is imperative to verify and control the mechanical properties through experimental tests. This study investigates an alternative test method, known as the Montevideo (MVD) test, by assessing SFRC properties with different fiber contents (0.5%, 0.75%, and 1.0%). The experimental program included three key aspects: i) determination of residual tensile loads and strength through the three-point bending (3PBT) test presented by NBR 16940/EN 14651; ii) determination of the residual tensile loads through the MVD test, correlatable with 3PBT results; iii) assessment of concrete in different ages: 28 days and 100 days. The results reveal a correlation factor (kMVD) that translates MVD test loads into values specified by NBR 16940/EN 14651, with a dependence on fiber content.
EMPLOYING THIN PLANAR ELECTRODES TO EXPAND THE IONIC WIND FLOW COVERAGE AREA AND ACHIEVE ENHANCED HEAT DISSIPATION
Authors: Ji Yu-Qing , Wang Jing , Xiao Shi-Chun , Shen Wen-Jie , Li An
Published: August 2024

The suboptimal photoelectric conversion efficiency of light-emitting diodes (LEDs) leads to increased temperature.
There is a growing interest in using microstructure ionic wind pumps to regulate the chip temperature. But the ionic
wind flow and thermal transfer characteristics of thin-plate electrode pumps used for cooling LED chips is unclear. This
study proposes ionic wind pumps equipped with wedged and zigzag emitters to effectively manage the heat generated by
high-power LED chips. Experimental investigations were conducted to analyze the electrohydrodynamic characteristics
of pumps with different emitter types. A two-dimensional model with a wedged electrode and a three-dimensional
model with a zigzag electrode were developed for flow distribution analysis and energy efficiency comparison. The
cooling capacity of pumps with different configurations was examined. The results show that the pump equipped with a
zigzag electrode exhibits improved stability in corona discharge and approximately 1.53 times higher energy efficiency compared to the pump with a wedged electrode. Moreover, the pump with the zigzag electrode covers a larger ionic wind flow area, generating a higher intensity of ionic wind. The angle between the emitter and the grounding electrode significantly affects the ionic wind flow characteristics. The optimal angle is 70° for pumps with wedged emitters and 30° for those with zigzag emitters. Both pumps can produce a steady wall jet at their optimal angle, causing significant disruption in the surrounding area. The pump with a zigzag electrode exhibits superior cooling performance and is more effective with low power consumption.
Effects of foam and activator contents on the properties of alkali-activated slag foamed concrete and a prediction model
Authors: He Juan , Gao Qie , Bai Wenbin , Zheng Weihao , He Junhong , Song Xuefeng , Sang Guochen
Published: August 2024

The influence of foam content and activator content on the properties of alkali-activated slag foamed concrete (AASFC) was studied. It was found that, when the foam content was increased from 3% to 12%, the effective foam ratio (EFR) and the water absorption of the AASFC increased, while the compressive strength and dry density decreased. For the same foam content, when the activator content was increased from 4% to 6%, the EFR and water absorption decreased, while the dry density increased. The AASFC showed good performance with an activator content of 5%. When the foam content was increased, the amount of large pores and interconnected pores increased. However, the foam content had little effect on the average pore size and pore roundness. For the same foam content, when the activator content was increased from 4% to 6%, the porosity and amount of interconnected pores decreased. With an increase in foam content from 9% to 12%, the porosity increased significantly and the thermal conductivity was significantly decreased. A property prediction model was established that may provide the foundation for AASFC mix design.
Anaphoric demonstratives occur with fewer and different pointing gestures than exophoric demonstratives
Authors: Skilton Amalia
Published: August 2024

This study investigates the co-organization of place-referring demonstratives (e.g. here/there) and pointing gestures by speakers of Ticuna. Ticuna is an Indigenous Amazonian language with a six-term demonstrative system which lexically distinguishes exophoric demonstratives (equivalent to there far from me) from anaphoric demonstratives (equivalent to there where I mentioned). This lexical contrast overlaps with, but is distinct from, the pragmatic contrast between new and previously mentioned referents. Drawing on a dataset of 742 demonstrative place references, I examine how both contrasts affect the rate and form of pointing gestures accompanying demonstratives. Pointing gestures were ubiquitous, occurring with 66.5% of demonstrative tokens. Ticuna participants pointed more often with exophoric demonstratives and with demonstratives that introduced new referents, but still pointed with a substantial minority of anaphoric demonstratives. Participants were also more likely to use index-finger handshapes with exophoric demonstratives, and to use full arm extension with demonstratives introducing new referents. These findings indicate that both lexical and information-structural factors affect the co-organization of pointing and demonstratives.
Contact load practices and perceptions in elite English rugby league: an evaluation to inform contact load guidelines
Authors: Parmley James , Weaving Dan , Whitehead Sarah , Brown James , Fairbank Laura , Flahive Sharron , Gardner Andrew , Hendricks Sharief , Johnston Rich , Mackreth Peter , Peacock Jamie , Phillips Gemma , Scantlebury Sean , Stein Josh , Stokes Keith , Till Kevin , Jones Ben
Published: August 2024

Background: Athlete exposure to contact could be a risk factor for injury. Governing bodies should provide guidelines preventing overexposure to contact.
Objectives: Describe the current contact load practices and perceptions of contact load requirements within men’s and women’s rugby league to allow the Rugby Football League (RFL) to develop contact load guidelines.
Methods: Participants (n=450 players, n=46 coaching staff, n=32 performance staff, n=23 medical staff) completed an online survey of 27 items, assessing the current contact load practices and perceptions within four categories: “current contact load practices” (n=12 items), “perceptions of required contact load” (n = 6 items), “monitoring of contact load” (n=3 items), and “the relationship between contact load and recovery” (n=6 items).
Results: During men’s Super League pre-season, full contact and controlled contact training was typically undertaken for 15-30 minutes per week, and wrestling training for 15-45 minutes per week. During the in-season, these three training types were all typically undertaken for 15-30 mins per week. In women’s Super League, all training modalities were undertaken for up to 30 minutes per week in the pre- and in-season periods. Both men’s and women’s Super League players and staff perceived 15-30 minutes of full contact training per week was enough to prepare players for the physical demands of rugby league, but a higher duration may be required to prepare for the technical contact demands.
Conclusion: Men’s and women’s Super League clubs currently undertake more contact training during pre-season than in-season, which was planned by coaches and is deemed adequate to prepare players for the demands of rugby league. This study provides data to develop contact load guidelines to improve player welfare whilst not impacting performance.
The Breeding colonies, population growth and breeding success of the Dalmatian pelican Pelecanus crispus in Greece: a country-wide perspective, 1967-2021
Authors: Catsadorakis Giorgos , Alexandrou Olga , Hatzilacou Dionyssia , Kasvikis Ioannis , Katsikatsou Maria , Konstas Spyros , Malakou Myrsini , Michalakis Dimitrios , Naziridis Theodoros , Nikolaou Haris , Noulas Nikolaos , Portolou Danae , Roussopoulos Yiannis , Vergos Ioannis , Crivelli Alain
Published: August 2024

Greece holds the third larger breeding population of Dalmatian Pelican in the world. We present data about the establishment and growth, breeding performance and conservation status for all six colonies of the species in Greece for 40 years. Main features of wetlands and colonies are described. We discuss the local, regional and global natural and anthropogenic factors that may have affected colony growth.
After 1982 colony surveys were carried out with various methods, adapted to the particularities of each wetland and availability of resources, and targeted estimating number of nests and number of near-fledged young via direct counting either during on-site visits or from vantage points, and recently, counts on photos taken by drones flown one or more times during breeding.
Number of nests in Lake Mikri Prespa rose from ca. 100 to 1200-1500 and levelled-off. DPs from Prespa started breeding successfully in Kerkini in 2004 after placement of artificial nesting rafts. The Karla Reservoir was colonised in 2011, just two years after it started filling with water. The DP colony on Lake Chimaditis, an important stop over and feeding site, probably initiated around 2016 and continues growing. The two colonies at the western coastline have limited exchanges with those in the eastern part of the country. Amvrakikos increased and levelled off recently as conservation and management measures restricted disturbance,  whilst emigrants re-established the old colony at Messolonghi in 2011 which continues to grow.  The overall breeding population in Greece grew from ca 100 to over 2000 br pairs showing an annual growth rate of 7.9%. Younger colonies show high annual growth rates clearly attributed to immigration, while older colonies have growth rates less than 10%.
Interacting natural and anthropogenic factors are assumed to have contributed to  pelican increase  in Greece the last 40 years: better legal protection status, increasingly effective protection, patrolling and conservation measures; public awareness campaigns; provision of artificial nesting structures; increased winter survival due to higher temperatures owed to climate change; less disturbance and persecution due to decline of fisheries; increasing abundance and availability of fish due to eutrophication and climate change; increasing numbers of sympatric great cormorants rendering pelican fishing more efficient; appearance of new wetlands and change of wetlands due to human intervention works.
Serum pentraxin-3 in patients with chronic obstructive pulmonary disease: A meta-analysis
Authors: Zhu Yan , Wang Chongyang
Published: August 2024

The association between serum pentraxin-3 (PTX-3) levels and chronic obstructive pulmonary disease (COPD) has been explored in several studies. However, the results remain inconsistent. This meta-analysis aims to evaluate the differences in serum PTX-3 levels between COPD patients and healthy controls, as well as between patients with acute exacerbations of COPD (AECOPD) and stable COPD. Databases including PubMed, Embase, Web of Science, Wanfang, and China National Knowledge Infrastructure (CNKI) were systematically searched. A random-effects model was used to pool the results, accounting for the potential impact of heterogeneity. Subgroup and meta-regression analyses were performed to evaluate the influence of study characteristics on the outcome. The initial search identified 274 articles, with 17 studies meeting the inclusion criteria. These studies included a total of 996 AECOPD patients, 1414 stable COPD patients, and 1016 healthy controls. The meta-analysis showed significantly higher serum PTX-3 levels in COPD patients compared to healthy controls (standardized mean difference [SMD]: 0.51, 95% confidence interval [CI]: 0.30 to 0.73, P < 0.001; I² = 85%). Subgroup and meta-regression analyses suggested that the results were not significantly affected by the age, sex, or smoking status of the patients. Additionally, serum PTX-3 levels were higher in AECOPD patients compared to stable COPD patients (SMD: 0.58, 95% CI: 0.41 to 0.74, P < 0.001; I² = 59%). In conclusion, serum PTX-3 levels are elevated in COPD patients, particularly during acute exacerbations, compared to stable COPD patients and healthy controls. PTX-3 may serve as a potential biomarker for COPD severity and exacerbation status.
Exploring the therapeutic potential of diterpenes in gastric cancer: Mechanisms, efficacy, and clinical prospects
Authors: Ma Chenhui , Gao Lei , Song Kewei , Gu Baohong , Wang Bofang , Pu Weigao , Chen Hao
Published: August 2024

Gastric cancer (GC) remains a significant global health challenge, particularly prevalent in East Asia. Despite advancements in various treatment modalities, the prognosis for patients, especially those in advanced stages, remains poor, highlighting the need for innovative therapeutic approaches. This review explores the promising potential of diterpenes, naturally occurring compounds with robust anticancer properties, derived from diverse sources such as plants, marine organisms, and fungi. Diterpenes have shown the ability to influence reactive oxygen species (ROS) generation, ferroptosis, and autophagy, positioning them as attractive candidates for novel cancer therapies. This review explores the mechanisms of action of diterpenes and their clinical implications for the treatment of GC. Additionally, it addresses the challenges in translating these compounds from preclinical studies to clinical applications, emphasizing the need for further research to enhance their therapeutic profiles and minimize potential side effects. The discussion underscores the importance of diterpenes in future anticancer strategies, particularly in the fight against gastric cancer.
USDA LTAR Common Experiment measurement: Butterfly diversity and abundance v1
Authors: M. Haddad Nick
Published: August 2024

We will use a measure of butterfly abundance and diversity collected using a method standard across the US and the globe (Wepprich, et al. 2019). This method is used in regional studies, for example, the states of Ohio, Illinois, and Michigan in the US and the countries of the UK, the Netherlands, and Spain. Within these regions across hundreds of sites, data collection is performed by scientists and citizen scientists. Butterflies are the easiest-to-measure indicator of pollinator and insect abundance; metrics from large-scale butterfly surveys have proven consistent with long-term responses of pollinators and other insects across the globe (Van Klink, et al. 2020). The recommended method is easily employed by people not trained with insects and is not burdensome in terms of time. For every replicate, it involves walking a 1 km line transect at least once a month and recording the number and species of butterflies within a set distance of the transect.
[RETRACTED] CrossRef Outage Prep, citations and versions v1
Authors: Frolov Vladimir
Published: August 2024

[RETRACTED]

Description example
AAV Production and Purification v1
Authors: T Savage Justin
Published: August 2024

This protocol is for the production and purification of Adeno-Associated Virus. The protocol contains the necessary steps to produce AAVs from HEK293T cell cultures.
This is how we do it in the field: photogrammetry as a fieldwork documentation tool on a Finnish archaeological project in Greece
Authors: Paukkonen Nikolai
Published: August 2024

Photogrammetric techniques have become commonplace in archaeology during the last two decades. During recent decades, the development of digital photography and the introduction of highly automated software with intuitive user interfaces has made 3D photogrammetry easily accessible for even the less-technologically adept fieldworkers. Archaeologists without special training in the technologies and theories behind photogrammetry can now produce accurate and visually impressive three-dimensional models of their research subjects. This article describes the measurement and documentation methodology used in an archaeological excavation project conducted in Photike, Greece, in 2021 by a Finnish-Greek cooperation. Photogrammetric modelling has been used in coordination with total stations in various contexts: in addition to documenting the uncovered architectural structures and remains, the method has also been applied to reproduce different stratigraphical phases of the excavation process, among other applications.
Exploring Adenosine Deaminase 1 (ADA-1) as a Novel Molecular Vaccine Adjuvant
Authors:   , Cusimano Gina Marie , Kutzler Michele A.
Published: August 2024

Vaccines are the most efficient and cost-effective tool for promoting health. Some vaccine platforms such as protein subunit are often insufficiently immunogenic without adjuvants. Vaccine adjuvants allow for antigen dose sparing, the generation of rapid and durable immune responses and the increase of vaccine effectiveness. There are few adjuvants acceptable for human use and limited knowledge of their mechanisms of action highlighting the need for adjuvant development and study. SARS-CoV-2 vaccines aided in curbing the COVID-19 pandemic which is an unquestioned success in the field. However, several studies have since shown rapid waning humoral responses, decreased efficacy particularly against variants of concern, and a lack of durable immune responses that protect against mild symptomatic disease. Despite many years of attempts, there is still no immunogen or adjuvant capable of inducing robust broadly neutralizing antibodies against HIV needed for protective immunity. There is a continued need for SARS-CoV-2 and HIV vaccines and adjuvants that induce durable protective immunity. Here we evaluated a novel molecular adjuvant adenosine deaminase 1 (ADA-1) in the context of a SARS-CoV-2 and HIV DNA vaccine. ADA-1 has known immunomodulatory properties and importantly, is critical for T follicular helper (TFH) cell function. TFH cells are a necessary component of germinal center reactions needed for effective humoral immune responses. We show that ADA-1 enhances the magnitude and durability of anti-SARS-CoV-2 humoral and cellular responses in mice that translates to increased protection upon challenge. We also demonstrate that ADA-1 enhances HIV specific humoral and cellular responses in mice. Mechanistically we demonstrate that recombinant ADA-1 protein enhances IL-6 and TNFα expression in macrophages. Taken together these data demonstrate that ADA-1 effectively adjuvants several DNA vaccine antigens and provides support for further translational studies.
Examining the Completeness of Industry and Occupation Data Among Patients Newly Diagnosed with Cancer in North Carolina
Authors: Angelon-Gaetz Kim , Ikhile Osaremhen , Gordon Howard R. D. , Pearson Melissa , Rao Chandrika
Published: August 2024

Background

Occupational exposure to toxic substances has been associated with cancer. Including industry and occupation (I/O) in cancer surveillance can help identify potential links between occupational exposures and cancers using data already collected to monitor statewide cancer trends. I/O reporting is required in cancer registries and recently in death records. In this study, we examined the completeness of I/O information in North Carolina cancer and death certificate data.

Methods

The North Carolina Central Cancer Registry (NC CCR) is the sole repository of North Carolina cancer incidence data. NC CCR (2020–2021) and death certificate data (2020–2022) were analyzed for completeness of I/O. NC CCR incidence records for 1995–2021 diagnoses were linked to North Carolina death files (2020–2022).

Results

NC CCR data had I/O in 17% to 51% of the cases, depending on cancer type. I/O was included in 41% of 2020 death certificates and increased to a 99.9% inclusion in 2021 and 2022 death certificates. In 2020, 20,018 (18%) of 109,677 total deaths matched with a cancer record during NC CCR data linkage. In 2021, 20,225 (16%) of 119,237 total deaths matched with a cancer record, and in 2022, 20,367 (17%) of 116,406 total deaths matched to a cancer record.

Limitations

Data presented here only examine the completeness of 10 cancer types that the NC CCR regularly analyzes using the most recent data available (2021).

Conclusion

Health care providers should routinely record I/O using the standards explained in the training for providers on I/O data collection, provided by the North Carolina Department of Health and Human Services, and should increase their frequency of reporting I/O to NC CCR. Death certificate data may provide I/O data for individuals whose information is missing from cancer registry data.
The Prevalence of Adverse Childhood Experiences in Ohio: Changes from 2015 to 2019
Authors: Carney-Knisely Geoffrey , Knudsen Kraig J. , Orack Joshua , Linley Jessica
Published: August 2024

Background: Adverse childhood experiences (ACEs) are associated with long-term negative health outcomes including substance use and mental health disorders. Little is known about how exposure to ACEs impacts health care access in adulthood.
Methods: We examined the prevalence of ACEs in 2015 and 2019 in Ohio. We analyzed relationships between ACEs and self-reported health outcomes, with a focus on health care access and utilization. We examined the 2015 and 2019 Behavioral Risk Factor Surveillance System (BRFSS) data from 14 247 persons who resided in Ohio. We stratified participants by ACE prevalence and assessed demographic differences between groups. Multivariable and multinomial logistic regression models were used to analyze health-related outcomes of interest.
Results: The prevalence of experiencing any ACE increased from 2015 to 2019, from approximately 62% to 68%. Exposure to ACEs was associated with smoking (OR = 3.167), binge drinking (OR = 3.259), and heavy drinking (OR = 4.455). Persons with any ACEs had increased odds of no health insurance (OR = 1.435) and increased odds of not having a doctor for any reason (OR = 1.722). Persons with 3 ACEs had 4.307 times the odds of depression, and this increased to 8.250 among persons with 5 or more ACEs. There was no association between ACEs and hypertension, cancer, heart attacks, stroke, and diabetes.
Conclusion: These findings support the hypothesis that ACEs have a long-term effect on health and access to health care. Findings from this study may inform interventions to reduce the incidence and long-term sequelae of ACEs.
Virtual articulator and virtual facebow an aid in complete digital workflow: A review article
Authors: Chirimar Vidit , Trivedi Anshul , Saxena Deepesh
Published: August 2024

Digital dentistry has been at the forefront of modernisation in dental practises. The aim of current dental practises is to provide an aesthetically pleasing and fast treatment options for improved patient satisfaction. Integration of CAD-CAM in dental prosthesis designing has helped achieve these goals. But a big drawback of unwanted occlusal discrepancies has been ignored for long. The development of the Virtual Articulator software has helped solve this problem by allowing the visualisation of occlusal contacts in static as well as dynamic conditions in the CAD software. Newer techniques of setting up Virtual Articulators leading to complete digitization of designing process have been discussed along with the future potential of integrating 3D and 4D haptic based technologies in the software for better dental education.
Fixed implant treatment options in edentulous patients: A review of the literature
Authors: Singh Virendra Pratap , Goswami Roma , Bali Yashika
Published: August 2024

Conventional complete denture therapy is considered the most basic and initial treatment option for edentulism. However, it is not without its complications, including denture stomatitis, traumatic ulcers, irritation-induced hyperplasia, altered taste perception, burning mouth syndrome, and gagging. Moreover, the treatment outcomes may not meet the individual's psychological or social needs, leading patients to seek alternative treatment options. Dental implants have emerged as a more favourable treatment option, offering various techniques such as all-on-4, all-on-6, zygomatic implants, and patient-specific implants. These techniques provide patients with better treatment outcomes and meet their individualized needs. All-on-four concept that employs tilted implants to restore edentulous patients has also been proposed as an alternative to bone augmentation procedures. The placement of four implants, two implants tilted posteriorly and two vertical implants in the anterior region, allows for avoiding bone augmentation procedures when rehabilitating a completely edentulous jaw with minimal bone volume.The All-on-six concept has evolved recently and provides better anchorage and support. Also, zygomatic implants have also been proven to be an effective treatment modality for the treatment of atrophic and highly resorbed mandibular ridges and in maxillectomy cases.
Expansion of Piped Water and Sewer Networks: The Effects of Regulation. Preliminary Findings
Authors: Tojal Ramos Dos Santos Carolina , Morais Guidetti Bruna
Published: August 2024

Expansion of piped water and sewage collection is a critical issue in developing countries, where public investment is limited. In Brazil, the New Sanitation Regulatory Framework from 2020 intends to stimulate the entry of private providers into the market while setting connection targets: 99% of households with piped water and 90%with piped sewer. We assess the viability of these connection goals under the current regulated prices and compare the distributional impacts of supplemental policies. We use billing data from a major private provider and a structural model encompassing the expansion decisions of the service provider and the connection and consumption choices of consumers. We find that even if the firm expanded water and sewer everywhere, the targets would not be met, with only 43% connecting to piped sewage. Moreover, the expansion is not profitable for the firm. We then simulate charging consumers when piped sewage is available, regardless of connection, and price discounts on the sewer bills. Combinations of these two policies stimulate the firm to expand and consumers to connect, achieving 76% connected to sewer but reducing consumer surplus.
PERFORMANCE PREDICTION OF STEEL FIBER-REINFORCED RECYCLED AGGREGATES CONCRETE DEEP BEAMS WITH WEB OPENINGS
Authors: Kachouh Nancy , El-Maaddawy Tamer , El-Hassan Hilal , El-Ariss Bilal
Published: August 2024

This paper aims to predict the shear strength of reinforced concrete (RC) deep beams containing web openings made with recycled concrete aggregates (RCAs) and steel fibers. Four numerical deep beam models were developed and verified against published experimental data. Three beam models had a 100% RCA replacement ratio, whereas one beam model was made with natural aggregates (NAs). One of the RCA-based beam models included steel fibers, one beam had internal steel stirrups, and the third beam was kept without steel fibers nor steel stirrups. The simulation models adopted a tensile softening law established through an inverse analysis of flexural test data of concrete prisms. The accuracy of published analytical formulas was also examined. The ratio of the shear strength predicted numerically to that measured experimentally was 0.89 to 1. Existing analytical formulas examined in this study overestimated the shar capacity of the tested deep beams by up to 49%.
An Overview of Abdominoplasty
Authors: Taner Ömer Faruk
Published: August 2024

The number of tummy tuck surgeries has recently increased significantly, largely due to the rise in bariatric surgery procedures. This surgical procedure is undertaken for both functional and aesthetic reasons. Several surgical techniques may be employed in the performance of an abdominoplasty. Most techniques are based on the excision of the skin in the lower abdomen and the stretching of the skin in the upper abdomen to cover the resulting defect. It is not feasible to utilize a singular technique for each patient. A meticulous assessment of the patient is imperative in determining the optimal technique. The advent of liposuction has provided a valuable adjunct to surgical intervention. This article outlines the evolution of abdominoplasty and the role of liposuction techniques in its development. Furthermore, the outcomes of the surgical method for reducing abdominal flap thickness by tangential excision of the abdominal flap before the advent of liposuction techniques are presented. Abdominal contouring procedures offer patients not only an enhancement in their appearance but also an improvement in their quality of life. Despite the numerous options, it is crucial to select a body contouring procedure that is safe and effective by evaluating the needs and expectations of each patient.
El giro humanitario en la búsqueda de los desaparecidos en América Latina: El caso del Perú
Authors: Rivas Belloso Jairo
Published: August 2024

En los últimos cincuenta años, un número importante de países latinoamericanos ha enfrentado periodos en los que se produjeron violaciones masivas a los derechos humanos de sus respectivas poblaciones, sea en regímenes dictatoriales, durante conflictos armados internos o en el combate contra el crimen organizado (México). Una de las consecuencias trágicas derivadas de estos contextos es la práctica de desaparición masiva de personas, principalmente por parte de agentes del Estado, pero también por el accionar de actores armados no estatales. Las denuncias planteadas por los familiares de las personas desaparecidas y los organismos de derechos humanos han tenido el efecto de generar obligaciones para los Estados relacionadas con la determinación del paradero de estas víctimas. En los últimos años, esta responsabilidad ha devenido en la creación de entidades gubernamentales  especializadas en la búsqueda de los desaparecidos. Bajo el influjo del humanitarismo, estas entidades no pretenden probar el delito ni identificar a los responsables, sino más bien entregar respuestas a los familiares que, por largo tiempo, desconocen el destino final de sus seres queridos. Este artículo, luego de describir la tarea pendiente en materia de búsqueda de las personas desaparecidas, describe el reciente giro humanitario que ha cobrado esta tarea en América Latina y establece un balance inicial respecto a sus posibilidades y limitaciones cuya principal referencia es la experiencia peruana.
Panorama de algunas representaciones sobre el conflicto armado interno en el cine peruano
Authors: Bedoya Wilson Ricardo
Published: August 2024

En este texto se traza una visión panorámica de algunas de las representaciones sobre el conflicto armado interno ofrecidas por el cine peruano desde fines de los años ochenta del siglo pasado hasta la actualidad. A partir de la mención de algunos títulos emblemáticos se señalan las coincidencias y divergencias mostradas en las perspectivas y tratamientos cinematográficos de la violencia política en el Perú a lo largo de los años.
Holigan incidents as an aggravating circumstance of criminal punishment
Authors: Lapshin Valery F. , Kemova Natalya N.
Published: August 2024

Subject of research: hooligan motives (motive) as a qualifying feature of a crime and an aggravating circumstance.
Purpose of research: to justify the need to include the fact of committing a crime for hooligan motives in the list of circumstances aggravating punishment.
Methods and objects of research: when conducting the research, general scientific and special scientific methods of cognition were used, which are mainly used in the humanities (legal) sciences: dialectical method, analysis, synthesis, formal-logical, systemic-structural, etc. The object of the research was social relations, which are formed when assessing the degree of public danger of a criminal act committed out of hooligan motives, for the subsequent imposition of a fair punishment for its commission.
Main results of research: any crime committed with hooligan motives is characterized by an increased degree of public danger. If the corpus delicti does not include hooligan motives as a qualifying feature, then this motive must be taken into account when assigning punishment. The results of the study can be used for research in the field of means of differentiation and individualization of criminal liability.
Building a knowledge ecosystem based on it-infrastructure of system research in energy
Authors: Massel Liudmila V. , Massel Aleksei G.
Published: August 2024

Purpose of research: building a Knowledge Ecosystem in the field of energy.
Object of research: energy facilities and systems and the fuel and energy complex as a whole.
Subject of research: methods and technologies for building knowledge ecosystems.
Methods of research: mathematical and semantic (including ontological) modeling, methods for constructing knowledge bases and tools (services) for working with them.
Main results of research: the possibility of using the IT- infrastructure of systemic research in the energy field as a scientific prototype of the Knowledge Ecosystem in the energy sector is shown. The basic concepts of knowledge ecosystems are discussed using a review of foreign sources. The possibility of using the IT-infrastructure of system research in the energy sector as a scientific prototype of the knowledge ecosystem in the energy sector is shown. The development of a Knowledge Ecosystem in the energy sector is proposed based on the IT infrastructure of systems research in the energy sector and its architecture is presented, including models, tools and digital twins.
Assessing suprasegmental phonology instruction in Ibnsaad school in Tlemcen: Case of Stress
Authors: Sidahmed Addou , Mohamed Dib
Published: August 2024

Poor quality teaching of the suprasegmental phonology in the Algerian secondary school cannot go unnoticed. A scrutiny of the Algerian ‘English as a Foreign Language’ (EFL) classroom can reveal some anomalies and serious deviations in the sound system instruction. The purpose of this research is to examine the ways phonology and phonological stress, in particular, are generally perceived and taught in the Algerian secondary school. To this effect, three research instruments, a questionnaire for teachers, open-ended questions for students, and a structured interview with a general inspector of English were administered. The data collected were carried out quantitatively and qualitatively. The results revealed important deficiencies in phonology instruction, owing to such factors as teaching misconceptions, the teacher’s defective in-service training regarding phonology, and insufficient teaching time allotment. The research concludes with a set of mechanisms that could be embedded in teaching and assessing prosodies to enhance phonology instruction.
Keywords: Assessment; prosodic features; stress; suprasegmental phonology; teaching.