bluuebunny/crossref_metadata_2025 huggingface dataset:
The Discriminatory Power of Vocal Features in Detecting Mental Illnesses Under Complex Context
Authors: Pan Wei , Shenhav Liat , Afshan Amber , Alwan Abeer , Flint Jonathan , Liu Tianli , Hu Bin , Zhu Tingshao
Published: March 2021

Background: Vocal features have been proposed as a way to identify depression by distinguishing depression from healthy controls, but while there have been some claims for success, the degree to which changes in vocal features are specific to depression has not been systematically studied. In particular, it is not clear whether vocal features are characteristic of mental ill health in general, rather than characteristic of different psychiatric diagnoses. We examined the performance of vocal features in recognizing three diseases (depression, schizophrenia and bipolar disorder) in comparison with healthy controls and in pairwise comparison with each disease in turn.Methods: We sampled 32 bipolar disorder patients; 106 depression patients, 114 healthy controls and 20 schizophrenia patients. We extracted i-vectors from MFCCs features, and built logistic regression models with ridge regularization and 5 fold cross validation on the training set, then applied models to the test set.Results: Our results showed that AUC score for classifying depression and bipolar disorder is 0.5 (F-score = 0.44). For other comparisons, AUC scores range from 0.75 to 0.92 (F-score ranges from 0.73 to 0.91). The performance (AUC) of depression and bipolar disorder classification model is significantly worse than the performance of bipolar disorder and schizophrenia classification model (corrected P < 0.05). We found no significant difference in pairwise ROC difference tests among the remaining classification tasks.Conclusions: Vocal features have robust discriminatory power not only in classifying depression and health, but also in pairwise classification among different mental illness.
Transcription of the Hydrogenase Gene during H2 Production in Scenedesmus Obliquus and Chlorella Vulgaris
Authors: Ordóñez Yahaira de Jesus Tamayo , Gutiérrez Benjamin Abraham Ayil , Marin Alejandro Ruiz , Ordóñez Francisco Alberto Tamayo , Davila Ileana Maria Mayela Moreno , González Leopoldo Ríos , Garza Jose Antonio Rodriguez de la , Heredia Juan Carlos Robles , Ordoñez Maria Concepcion Tamayo
Published: March 2021

There is ongoing research related to the production of molecular hydrogen today and algae have proven to be good biological models for producing several compounds of interest. We analyzed how genetic variations in hydrogenase genes (hyd) can affect the production of molecular hydrogen in the algae Chlorella vulgaris and Scenedesmus obliquus. Through isolation and genetic characterization of hyd genes in S. obliquus and C. vulgaris, we made in-silico 3D modeling of the hydrogenase proteins and compared these in 11 algal genera. The 3D structure of hydrogenases indicated its structural conservation in 10 genera of algae, and the results of our grouping according to the aa characteristics of the proteins showed the formation of two groups, which were unrelated to the algae’s phylogenetic classification. By growing C. vulgaris and S. obliquus in anaerobic conditions (in darkness) during 24 h and after exposing the cultures to light, we observed H2 production values of 9.0 ± 0.40 mL H2/L and 16 ± 0.50 mL H2/L, respectively. The highest global relative expression of hyd genes was reached during the first 30 min of exposure to light. The behavior of the expression of the hyd genes in these species of algae proved to be species specific and involved in the production of H2. Future identification of isoforms of hyd genes in algae would allow a better understanding of the regulation of the hydrogenase enzyme.
Performance Evaluation of symmetric 8×10 Gbps TWDM-PON incorporating Polarization Division Multiplexed Modulation Techniques under fiber-impairments
Authors: Kumari Meet , Sharma Reecha , Sheetal Anu
Published: March 2021

Today’s access networks are in high demand to fulfill the high bandwidth requirement because of extensive improvement in high transmission rate applications for cloud computing, big data analytics, and other next-generation 5G smart applications. This exponential growth of high capacity and broadband access technologies comprise an essential trend in the development of a passive optical network (PON) access network. In this paper, 80/80 Gbps time wavelength division multiplexing PON (TWDM-PON) incorporating polarization division multiplexing (PDM) based Mach-Zehnder modulator (MZM) and electroabsorption modulator (EAM) techniques have been proposed. The performance of the system consisting of different polarized multiplexed modulation techniques is investigated in both downstream and upstream data transmission for variable transmission distance and received optical power in terms of bit error rate (BER), eye diagrams, power budget (PB) and receiver sensitivity (RS). The results show that the 4×20/20 Gbps PDM-EAM modulated signals over 100 km fiber distance at -60 dBm RS and 70 dB PB are successfully transmitted under fiber non-linearities. The proposed TWDM-PON system provides a next-generation long-reach access network from urban to rural areas.
Congestion Management in Deregulated Power System using Adaptive Moth Swarm Optimization
Authors: Ramaporselvi R , Geetha G.
Published: March 2021

The authors have requested that this preprint be removed from Research Square.
A Robust 3D Self-powered Photoelectrochemical type Photodetector based on MoSe2 Nanoflower
Authors: Wang Kai , Wu Jie , Chen Gexiang , Qiao Hui , Zhou Yang , Li Jun , Qi Xiang
Published: March 2021

Molybdenum selenide (MoSe2) has been extensively studied in recent years due to its strong absorption for sunlight and unique band structure. Herein, a self-assembly three-dimensional (3D) MoSe2 nanoflowers were prepared by a two-step process. Significantly, the photodetection device based on MoSe2 nanoflowers exhibited a maximum responsivity about 12.39mA/W and a rapid photo-response time about 0.15s at 0V bias under simulated sunlight exposure benefiting from its large specific surface area and unique morphologic structure. Meanwhile, we demonstrated the outstanding stability after two weeks of the photodetection device. In this way, the MoSe2 nanoflower-based photodetectors enriched the basic research of molybdenum selenide and provided some reference for the following researches based on molybdenum selenide.
Enhanced-coherence all-nitride superconducting qubit epitaxially grown on Si substrate
Authors: Kim Sunmi , Terai Hirotaka , Yamashita Taro , Qiu Wei , Fuse Tomoko , Yoshihara Fumiki , Ashhab Sahel , Inomata Kunihiro , Semba Kouichi
Published: March 2021

We have developed superconducting qubits based on NbN/AlN/NbN epitaxial Josephson junctions on Si substrates which promise to overcome the drawbacks of qubits based on Al/AlOx/Al junctions. The all-nitride qubits have great advantages such as chemical stability against oxidation (resulting in fewer two-level fluctuators), feasibility for epitaxial tunnel barriers (further reducing energy relaxation and dephasing), and a larger superconducting gap of ~ 5.2 meV for NbN compared to ~ 0.3 meV for Al (suppressing the excitation of quasiparticles). Replacing conventional MgO by a Si substrate with a TiN buffer layer for epitaxial growth of nitride junctions, we demonstrate a qubit energy relaxation time \({T}_{1}=16.3 {\mu }\text{s}\) and a spin-echo dephasing time \({T}_{2}=21.5 {\mu }\text{s}\). These significant improvements in quantum coherence are explained by the reduced dielectric loss compared to previously reported NbN-based qubits with MgO substrates (\({T}_{1}\approx {T}_{2}\approx 0.5 {\mu }\text{s}\)). These results are an important step towards constructing a new platform for superconducting quantum hardware.
Multi-Scale Coherent Magnetic Field from Atomic Medium to L1544 Molecular Core
Authors: Ching Tao-Chung , Li Di , Heiles Carl , Li Zhi-Yun , Qian Lei , Yue Youling , Tang Jing , Jiao Sihan
Published: March 2021

Magnetic fields play an important role in the evolution of interstellar medium and star formation. As the only direct tracer of interstellar field strength, credible Zeeman measurements remain sparse due to rather limited number of spectral lines with discernible Zeeman effect, particularly for cold, molecular gas. Here we report the detection of a magnetic field of 3.8 ± 0.3 μG through a new tracer, the HI narrow self-absorption (HINSA), toward the prestellar core L1544 of the Taurus molecular cloud using the Five-hundred-meter Aperture Spherical radio Telescope (FAST). A combined analysis of the Zeeman measurements of quasar HI absorption, HI emission, OH emission, and HINSA reveals a coherent magnetic field from the atomic cold neutral medium (CNM) to the molecular envelope of the L1544. We find that the molecular envelope traced by HINSA is already magnetically supercritical, with a field strength comparable to that in the surrounding diffuse, magnetically subcritical CNM despite a large increase in density. The reduction of the magnetic flux relative to the mass, necessary for star formation, thus seems to happen during the transition from the diffuse CNM to the molecular gas traced by HINSA, earlier than envisioned in the classical picture where magnetically supercritical cores capable of collapsing into stars form out of magnetically subcritical envelopes. The HINSA Zeeman effect opens up a new window on the interstellar magnetic field that is poised for rapid growth in the era of Square Kilometer Array and its precursors.
The 16S rRNA gene sequencing of gut microbiota in chickens infected with different virulent Newcastle disease virus
Authors: Tong Lina , Ren Shanhui , Wang Wen , Wang Jianling , Wang Jie , Qu Yang , Adam Fathalrhman Eisa Addoma , Li Zengkui , Yang Zengqi , Gao Xiaolong
Published: March 2021

Background

Newcastle disease virus (NDV) is pathogenic to chickens, which is characterized by dyspnea, diarrhea, nervous disorder and hemorrhages. However, the influence of different virulent NDV infection on the host gut microbiota composition is still poorly understood. In this study, twenty 21-day-old specific pathogen free chickens were inoculated with either the velogenic Herts33 NDV strain, lentogenic La Sota NDV strain or sterile phosphate buffer solution (PBS). Through 16S rRNA sequencing, the collected fecal samples of control and NDV infected chickens were examined.
Results

The results showed that the gut microbiota were mainly dominated by Firmicutes, Bacteroidetes and Proteobacteria in both healthy and NDV infected chickens. NDV infection altered the structure and composition of gut microbiota. As compared to PBS group, phylum Firmicutes were remarkably reduced, whereas Proteobacteria was significantly increased in velogenic NDV infected group. While the gut community structure has no significant differences between lentogenic NDV infected group and PBS group at phylum level. At genus level, Escherichia-Shigella was significantly increased in both velogenic and lentogenic NDV infected groups, but the lactobacillus was only remarkably decreased in velogenic NDV infected group. Collectively, different virulent NDV infection resulted in a different alteration of the gut microbiota in chickens, including a loss of probiotic bacteria and a expansion of pathogenic bacteria.
Conclusion

These results indicated that NDV with different virulence have different impact on chicken gut microbiota and may provide new insights into the intestinal pathogenesis of NDV.
Superlubric Polycrystalline Graphene Interfaces
Authors: Gao Xiang , Ouyang Wengen , Urbakh Michael , Hod Oded
Published: March 2021

The effect of corrugated grain boundaries on the frictional properties of extended graphitic contacts incorporating a polycrystalline surface are investigated. The friction is found to be dominated by shear induced buckling and unbuckling of corrugated grain boundary dislocations, leading to a nonmonotonic behavior of friction with normal load and temperature. The underlying mechanism involves two competing effects, where an increase of dislocation buckling probability is accompanied by a decrease of the dissipated energy per buckling event. These effects are well captured by a phenomenological two-state model, that allows for characterizing the tribological properties of any large-scale polycrystalline layered interface, while circumventing the need for demanding atomistic simulations. The resulting negative differential friction coefficients obtained in the high-load regime can reduce the expected linear scaling of grain-boundary friction with surface area and restore structural superlubricity at increasing length-scales.
Radiation Synthesis and Characterization of Poly(Vinyl Alcohol)/ Acrylamide/ TiO2/ SiO2 Nanocomposite for Removal of Metal Ion and Dye From Waste Water
Authors: Elbarbary Ahmed , Gad Yasser H.
Published: March 2021

An effective and novel adsorbent of poly(vinyl alcohol)/polyacrylamide/TiO2/SiO2 (PVA-co-AAm/TiO2/SiO2) nanocomposite synthesized by γ-irradiation polymerization of PVA and AAm in presence of TiO2/SiO2 nanoparticles at different irradiation doses (10, 30 and 50 kGy) for removal of Cu(II) ions and basic blue 3 dye from their aqueous solutions. FT-IR, TEM, XRD, SEM, EDS and DLS analyzed the chemical properties of nanocomposites. The nanocomposite prepared at 30 kGy (PVA-co-AAm/TiO2/SiO2-30) shows high swelling of 197.7 (%) and gelation of 93.1 %. The adsorption capacity (mg/g) and removal (%) of basic blue 3 dye and Cu(II) ions onto nanocomposites by varying experimental conditions were investigated. The PVA-co-AAm/TiO2/SiO2-30 showed high adsorption capacity 3 folds rather than PVA-co-AAm. The equilibrium adsorption for basic blue 3 dye and Cu(II) was 123.9 mg/g and 190.3 mg/g with removal of 82.6 and 95.1 %, respectively. The results of the adsorption of dye or metal ions follow the Pseudo-second order adsorption kinetic, fit with the Langmuir isotherm and the adsorption process is endothermic and spontaneous in nature. The results revealed that the PVA-co-AAm/TiO2/SiO2 nanocomposites could be employed as an effectual adsorbent for adsorption of basic blue dye and Cu(II) ions from wastewater with high adsorption capacity and recovery.
Based on bioinformatics analysis, NF1, BTRC and MAPK14 are the potential biomarkers in the progression of osteoarthritis synovitis
Authors: Yang Mingyi , Su Yani , Ma Yao , Aihaiti Yirixiati , Xu Peng
Published: March 2021

Objective: To study the potential biomarkers and related pathways in osteoarthritis (OA) synovial lesions, and to provide theoretical basis and research directions for the pathogenesis and treatment of OA. Methods: Download the microarray data sets GSE12021 and GSE82107 from Gene Expression Omnibus. GEO2R recognizes differentially expressed genes. Perform functional enrichment analysis of differentially expressed genes and construct protein-protein interaction network. Cytoscape performs module analysis and enrichment analysis of top-level modules. Further identify the Hub gene and perform functional enrichment analysis. TargetScan, miRDB and miRWalk three databases predict the target miRNAs of Hub gene and identify key miRNAs. Results: Finally, 10 Hub genes and 17 key miRNAs related to the progression of OA synovitis were identified. NF1, BTRC and MAPK14 may play a vital role in OA synovial disease. Conclusion: The Hub genes and key miRNAs discovered in this study may be potential biomarkers in the development of OA synovitis, and provide research methods and target basis for the pathogenesis and treatment of OA.
Factors influencing Research Engagement among Medical students in the United Kingdom (REMED-UK): protocol for a prospective, observational, national, multi-centre questionnaire - study
Authors: Osunronbi Temidayo , Adeboye William , Faluyi David , George Jasmine , Sofela Agbolahan
Published: March 2021

Introduction: There has been a decline in the number of academic clinicians in the UK. Also, there are gender and ethnic inequalities in research opportunities amongst UK clinicians. The decision to get involved in research as a clinician is usually made as a medical student. Hence, this study aims to investigate the factors affecting UK medical students’ involvement in research, and to understand their perceptions of research, motivation for and the barriers to their engagement in research.Methods: This study is a prospective, observational, national, multi-centre study that will utilise an online questionnaire using the QualtricsTM survey tool. Medical students that are at least 18 years old and enrolled in a UK medical school in the 2020/21 academic year are eligible to partake in this study. The following data will be collected: demographic, research experience, research perception, research self-efficacy, motivation, and barriers to engaging in research. The outcome measures are: number of research projects, publications, presentations, and successful grant applications.Conclusion: This study will produce evidence-based reports that will guide UK medical schools and relevant organisations in developing resources and programmes that will increase the number of future academic clinicians and resolve inequalities in research opportunities and engagement amongst future clinicians.
In Silico Characterization of Mate Genes in Wheat
Authors: Mohanta Deepika , Debnath Sandip
Published: March 2021

Background: Multidrug and toxic compound extrusion (MATE) genes are a group of multidrug efflux transporters that widely exists in all living organisms and play a major role in the detoxification of heavy metals, metalloids, exogenous xenobiotics and endogenous secondary metabolites out of the cells. However, insilico analysis of MATE gene family in plant species is very limited and thus such analysis need to be elucidated in wheat.Results: We have identified forty-four MATE genes in wheat and categorized into seven families based on their phylogenetic analysis. Further, 43 genes were found to exhibit protein-protein interaction at the protein level by using STRING software. We observed that the maximum number of exons i.e., 14 was identified in genes TraesCS6A02G418800.1 and TraesCS6D02G407900.1. We employed MEME software to find protein motifs associated with the MATE genes where maximum number of motifs were set to 22. Here, the protein motifs among the families 1,2 and 3 were significantly different from the rest. We found that the majority of MATE genes were showing expressions during biotic stress conditions due to disease infestations and the highest level of expression was shown by the gene TraesCS5B02G326600.1 belonging to family 1 which got expressed during Fusarium head blight infestation by Fusarium graminearum after 4 days of inoculation by using Wheat expression browser tool. A total of 39 ternary plots consisting of homoeologous genes for 39 MATE genes, showing different level of expressions during biotic and abiotic stress conditions were composed, where we found 44 % of the triads tend to show non balanced expressions (extreme values) due to their higher tissue- specificity and greater intensity.Conclusion: The results obtained from this study indicated that total 44 MATE genes were found to be directly involved in the metabolism of wheat and were expressed during different biotic and abiotic stress conditions. So such genes can be further evaluated for their interaction with heavy toxic metal elements and sequestration from the cells.
Protocol for a Process Evaluation of an External Pilot Cluster Randomised Controlled Trial of a Theory-Based Intervention to Improve Appropriate Polypharmacy in Older People in Primary Care: The PolyPrime Study
Authors: Rankin Audrey , Molloy Gerard J. , Cadogan Cathal A. , Barry Heather E. , Gorman Ashleigh , Ryan Cristín , Ferrett Alan , McCarthy Pat , Gormley Gerard J. , Fahey Tom , Hughes Carmel
Published: March 2021

Background
The PolyPrime intervention is a theory-based intervention aimed at improving appropriate polypharmacy in older people (aged ≥ 65 years) in primary care. The intervention consists of an online video which demonstrates how general practitioners (GPs) can prescribe appropriate polypharmacy during a consultation with an older patient and a patient recall process, whereby patients are invited to scheduled medication review consultations with GPs. The aim of the process evaluation is to further examine the implementation of the PolyPrime intervention in primary care. This will involve investigating whether the PolyPrime intervention can be delivered as intended across two healthcare systems, how acceptable the intervention is to GPs, practice staff and patients, and to identify the intervention’s likely mechanisms of action.
Methods
The PolyPrime study is an external pilot cluster randomised controlled trial (cRCT) which aims to recruit 12 GP practices across Northern Ireland [NI] (n = 6) and the six counties in the Republic of Ireland (ROI) that border NI (n = 6). Practices have been randomised to intervention or usual care. An embedded process evaluation will assess intervention fidelity (i.e. was the intervention delivered as intended), acceptability of the intervention to GPs, practice staff and patients, and potential mechanisms of action (i.e. what components of the intervention were perceived to be effective). Quantitative data will be collected from data collection forms completed by GPs and practice staff and a feedback questionnaire completed by patients from intervention arm practices, which will be analysed using descriptive statistics. Qualitative data will be collected through semi-structured interviews with GPs and practice staff and audio-recordings of medication review appointments from the intervention arm practices which will be transcribed and analysed using the framework method. Quantitative and qualitative data will be triangulated to provide an overall assessment of intervention fidelity, intervention acceptability and mechanisms of action.
Discussion
This process evaluation will add to feasibility data from the pilot cRCT by providing evidence on the fidelity of implementing the intervention package across two healthcare systems, the acceptability of the intervention and potential mechanisms of action.
Trial registration:
ISRCTN, ISRCTN41009897. Registered 19 November 2019, https://doi.org/10.1186/ISRCTN41009897. Clinicaltrials.gov, NCT04181879. Registered 02 December 2019, https://clinicaltrials.gov/ct2/show/NCT04181879.
Differential effect of statin use on coagulation markers: an active comparative analysis in the NEO study
Authors: Bordbar Mohammadreza , Mutsert Renée de , Cevval Melike , Rosendaal Frits R. , Jukema J. Wouter , Lijfering Willem M.
Published: March 2021

Background: Statins are a potential treatment for venous thromboembolism (VTE) prophylaxis complementary to conventional anticoagulants without associated bleeding complications. The aim of this study was to compare prothrombotic activities of different classes of lipid-lowering drugs in an active comparator design, and determine whether there is a relation between statin versus fibrate/niacin use and procoagulant factor outcomes.Methods: This is a cross-sectional analysis of participants from the Netherlands Epidemiology of Obesity study who were using any class of lipid-lowering drugs, including any types of statins, niacin, and fibrates. We performed linear regression analyses to determine the activity of fibrinogen, factor (F)VIII, FIX, and FXI in statins versus fibrate/niacin users and adjusted for age, sex, tobacco smoking, body mass index (BMI), hypertension, diabetes, and prevalent cardiovascular disease.Results: Among 1043 participants, the mean age was 58.39± 5.19 years, 61% were men, and mean BMI was 31.3± 4.5 kg/m2. Clinical characteristics were balanced between statin and fibrate/niacin users. Statin users had lower mean FVIII (15.8 IU/dL, 95% confidence interval (CI) -0.003 to 31.6), FIX (11.3 IU/dL, 95% CI -0.4 to 23.2) and FXI (18.3 IU/dL, 95% CI 9.4 to 27.3) levels, and higher mean fibrinogen levels (19.1 mg/dL, 95% CI -10.0 to 48.2) compared to fibrate/niacin users.Conclusion: Current statin use was associated with lower plasma levels of FVIII, FIX, FXI, and higher fibrinogen levels compared to fibrate/niacin use. These effects on coagulation factors may, in part, explain the benefit of statin therapy rendered in primary and secondary prevention of VTE.
ANALYSIS OF THE CURRENT STATE OF KAZAKHSTAN’S AGRICULTURE COMPETITIVENESS IN MARKET CONDITIONS
Authors:   L. N.Gumilyov Eurasian National University, Ryspekova М. , Duisenbekova А. ,   L. N.Gumilyov Eurasian National University
Published: March 2021

The article assesses the competitiveness of the country’s agriculture, which is necessary for establishment and sustainable development of Kazakhstan’s economy. The authors used the sectoral principle, i.e., the distribution by sector or activity area in agriculture, based on agricultural competitiveness classification. For agricultural producers environment implementation of investment process mechanism becomes prerequisites for organizing public investment procedures as functioning subjects of the national investment market. Nowadays the analysis of average indicators of food consumption such as the agricultural production structure by categories of farms, and the number and specific weight of breeding stock in all categories of households revealed problems regarding food security in Kazakhstan. It is concluded that taking into account all the plans and capacity utilization at the processing enterprises, there is an excellent potential for competitiveness in the Kazakh domestic market and even in foreign markets. In modern Kazakhstan conditions, theoretical and practical analysis of the competitiveness essence, its manifestation specifics can contribute to development of high-priority concerns which improve the efficiency of the market relations and economic success of Kazakh agricultural producers
Predictive geochemistry of ore gold in Eastern Transbaikalia
Authors:   Transbaikal State University, Pavlenko Yu.
Published: March 2021

The subject of the research is the methods of forecasting the Eastern Transbaikalia - a large mining region of Russia, in which the main internal and external criteria for ore content are established by modern geological mapping at a scale of 1:1,000,000. The article considers endogenous geochemical criteria for gold concentration in the Earth’s crust of the region, which constitute a mandatory methodological method for predicting gold ore objects at any scale. The aim of the work is to clarify the achieved level of knowledge about the mineralogical and geochemical criteria for gold concentration in the course of the evolution of the Earth’s crust up to the formation of industrial deposits and the isolation of ore formations. The methodology of the study is to systematize a huge amount of factual material concerning the processes of natural concentration of gold, to analyze its representativeness, to assess the completeness and reliability of published and stock information used to clarify the mineralogical and geochemical criteria for predicting ore gold. Using the chemical properties of gold, the forms of finding gold, amount of it in the forming geological complexes and natural environments, their evolution, distribution in structural and tectonic zones, some causes of concentration and mineralogical and geochemical prediction criteria are considered. Special attention is paid to the need to study and account for nanoscale (dispersed) gold. As the main ore-formation units of gold mineralization, standardized ore formations are defined with a division into gold ore proper, complex gold-bearing and gold-bearing and geological and industrial types of deposits. There are 15 geological and industrial types, of which 13 are transbaikal deposits standards and two are attracted from other regions. These types of deposits differ in the number of objects related to them. Due to some similarity in the composition of ore matter, geological and industrial types differ in the most important classification characteristics for the forecast. Areas of distribution of direct and indirect mineralogical and geochemical features grouped into mineralogical and geochemical forecast criteria are promising for endogenous concentration of gold mineralization
Hansischer Warenverkehr im Dreieck Lübeck - Hamburg - Lüneburg am Ende des 15. Jahrhunderts
Authors: Vogtherr Hans-Jürgen
Published: March 2021

Hansischer Warenverkehr im Dreieck Lübeck - Hamburg - Lüneburg am Ende des 15. Jahrhunderts
Transaktionskostentheorie und die hansische Geschichte
Authors: Link Christina , Kapfenberger Diana
Published: March 2021

Transaktionskostentheorie und die hansische Geschichte. Danzigs Seehandel im 15. Jahrhundert im Licht einer volkswirtschaftlichen Theorie.
Zwischen 'Globalisierung' und Konfessionalisierung
Authors: Cordes Albrecht , Graßmann Antjekathrin , Hammel-Kiesow Rolf
Published: March 2021

Einleitende Bemerkungen zur Sektion des Hansischen Geschichtsvereins auf dem 45. Deutschen Historikertag in Kiel 2004
Prof. Dr. Elisabeth Harder-Gersdorff
Authors: Graßmann Antjekathrin
Published: March 2021

Prof. Dr. Elisabeth Harder-Gersdorff 1932-2005
Hinrick van Hasselt, Rebell und Bergenfahrer aus Deventer
Authors: Wubs-Mrozewicz Justyna
Published: March 2021

Hinrick van Hasselt, Rebell und Bergenfahrer aus Deventer. Problemlösung im Kontor in Bergen in den 40er Jahren des 16. Jahrhunderts.
Risiken des Fernostgeschäfts
Authors: Wippich Rolf-Harald
Published: March 2021

Risiken des Fernostgeschäfts. Piratenüberfälle auf norddeutsche Handelsschiffe im Chinesischen Meer (1840-1870)
Verkehr und seine Wege im nordwestlichen Ostseeraum 10. bis 14. Jahrhundert
Authors: Zühlke Raoul
Published: March 2021

Der Verkehr und seine Wege im nordwestlichen Ostseeraum 10. bis 14. Jahrhundert. Alles über See?
A. H. de Oliveira Marques (1933-2007)
Authors: Denk Thomas
Published: March 2021

Nachruf
Bischof Meinhard von Üxküll: Ein friedlicher Missionar?
Authors: Zühlke Raoul
Published: March 2021

Bischof Meinhard von Üxküll: Ein friedlicher Missionar? Ansätze zu einer Neubewertung. Ein quellenkundlicher Werkstattbericht.
Späte Hanse und Altes Reich
Authors: Postel Rainer
Published: March 2021

Rainer Postel - Späte Hanse und Altes Reich
Hanse auf dem Weg zum Städtebund.
Authors: Seier Maria
Published: March 2021

Maria Seier - Hanse auf dem Weg zum Städtebund. Hansische Reorganisationsbestrebungen an der Wende vom 15. zum 16. Jahrhundert
Bergener Kontor im Mittelalter
Authors: Nedkvitne Arnved
Published: March 2021

Arnved Nedkvitne - Das Bergener Kontor im Mittelalter
Entgegnung auf Nedkvitne, Das Bergener Kontor, 2
Authors: Wubs-Mrozewicz Justyna
Published: March 2021

Justyna Wubs-Mrozewicz - Entgegnung auf Nedkvitne, Das Bergener Kontor, 2
Zur Tätigkeit der Prokuratoren vor dem Lübecker Rat gegen Ende des 15. Jahrhunderts
Authors: Seggern Harm von
Published: March 2021

Harm von Seggern - Zur Tätigkeit der Prokuratoren vor dem Lübecker Rat gegen Ende des 15. Jahrhunderts
Wie verlässlich ist das Artlenburg-Privileg überliefert?
Authors: Ellmers Detlev
Published: March 2021

Henry the Lion’s Artlenburg Charter (1161)The Artlenburg Charter of 1161, only transmitted in later copies, is unquestionably the most hotly disputed document of the twelfth Century. While one side views the charter as the founding document of the German Hanse, the other side focusses on the clauses inserted into the charter at a later date, which leads them to a completely different understanding of its significance. Among those in the latter group, Thomas Riis put forward the hypothesis that the Lübeck copy of the charter constitutes nothing less than an augmented version of the document with ,improving' additions to the text which was produced around 1225 by the Lübeck canon Marold, which Lübeck presented to Emperor Fredrich II in 1226 - together with a number of other Charters which Marold had ,improved‘ - in order to obtain the document known to scholars as the ,charter of imperial freedom’ (1226). The critical examination of Riis’s arguments demonstrates, however, that Lübeck never employed its copy of the Artlenburg charter to argue a point with an external authority, be it in 1226 or at any other subsequent time. This raises the question of why. and for whom, the copy was made. The town seal appended to the charter proves indubitably that it was executed on a mandate from the Lübeck town council. It was this body which ordered the Artlenburg charter (together with Henry the Lion’s mandate to the advocate charged with governing the German merchants on Gotland) to be copied into Lübecks Codex of Privileges, which was reserved for confidential use by councillors and merchants. The copy of the charter served to inform them of the conditions under which a permanent, peaceful settlement of the conflicts between Germans and Gotlanders had been reached under the tutelage of Henry the Lion, a settlement which opened trade in the Baltic for merchants sailing from Lübeck. The purpose of the copy was to keep Lübeck’s merchants precisely informed of each and every right they enjoyed (since these constituted the foundation of their trade), in order to be able to maintain those rights if conflicts arose in the future. Any change to the original text would have been suicidal. Therefore, we can be confident that the text which the copy transmits corresponds to the (lost) original in each and every particular.
Hansische Niederlassungen in Russland um 1600
Authors: Iwanow Iwan
Published: March 2021

Hanseatic Trading Posts in Russia around 1600When Novgorod was absorbed into the Grand Principality of Moscow in 1478, the traditional medieval framework of Hanseatic trade with Russia was transformed. Henceforth, negotiations and decisions on all important questions took place in Moscow, while the day to day problems of trade lay within the purview of the Great Prince’s (later: the Tsar’s) lieutenant residing in Novgorod. Given the abolition of the medieval structures of communication, Hanseatic representatives suddenly required an intimate familiarity with the Russian court in order to conduct successful negotiations. This article argues that the interaction between Hansards and Russians is best understood as a continuing process of accomodation to one another, and focusses initially on the by-laws (Schra) of the Novgorod Kontor, which were continuously amended and supplemented. Initially, these changes were endogenous, resulting from internal tensions within the Hanse itself. Over time, however, the transformation of the Russian environment became more important. Indeed, many of the new rules and regulations inserted into the by-laws can be best understood if they are conceived to be exogenous, imposed on the Kontor from outside. The article then examines in detail the Hanseatic embassy to Moscow in 1603 and demonstrates how the mutual trust between the Hansards and the Tsars arose and how it was strengthened and developed.
History of the 'Hanse Cog'
Authors: Paulsen Reinhard
Published: March 2021

Contents1. Municipl cogs: “Germany at Sea”2. From a state-like to a völkisch-Nordic Hanse3. The invention of a “Hanse cog” in NS-times4. The “Economic Miracle Hanse”5. “Hanse cog” : setting the post-war course6. The discovery of the Bremen ship in 19627. A Frisian-cog- and a Hanse-cog-legend8. Gradual retreat of the Hanse and shipping research9. The state of medieval shipping research10. Outlook
Kölns Beziehungen zu den Städten an der Zuiderzee
Authors: Militzer Klaus
Published: March 2021

Fish (hering, in particular) and wine arrived on the Cologne market in the autumn, as a rule, coming from the north and the south respectively, and were distributed from there. If the Zuiderzee towns had complaints about wines they had received, they contacted Cologne. The same was true of the towns on the upper Rhine if fish was defective. Cologne forwarded the complaints to their point of origin. But Cologne witnessed a significant confluence of ideas and influences in other ways too. It attracted immigrants and students from the IJssel and Zuiderzee towns, as the burse at the university demonstrate.
Hanseatic merchant Heinrijc Hoep (†1466) and his precious book of sermons
Authors: Zwart Cora
Published: March 2021

Die Staatsbibliothek Preußischer Kulturbesitz zu Berlin, ehemalige Deutsche Staatsbibliothek in Ost-Berlin, besitzt seit dem Jahr 1967 die reich illuminierte, aber bislang eher unbekannte Handschrift eines Predigtbuches (Berlin, SBB-PK, Ms. germ. fol. 1612). Vereinzelte anfängliche kunsthistorische und linguistische Untersuchungen des Manuskripts in den 1980er Jahren haben einige spezifische Eigenschaften des Bandes herausgearbeitet, jedoch nicht den Erstbesitzer oder sein ursprüngliches gesellschaftliches Umfeld ermitteln können. Mutmaßlich soll es sich um einen Einwohner von Utrecht, eine Person, die mit den Brüdern der Devotio Moderna in Verbindung stand oder um eine Person aus den nordöstlichen Niederlanden gehandelt haben.

Dieser Beitrag nimmt erstmals die drei distinktiven Eigenschaften des Manuskripts gemeinsam in den Blick: den Besitzvermerk, die Buchmalereien und die spezifische Sprachvariante. Dadurch gelang es, die ersten Besitzer des Bandes zu identifizieren und ihn überraschenderweise im Umfeld von Hansekaufleuten in den südlichen Niederlanden im 15. Jahrhundert zu situieren.
Thanatomicrobiome – State Of The Art And Future Directions
Authors: Wójcik Joanna , Tomsia Marcin , Drzewiecki Artur , Skowronek Rafał
Published: March 2021

Microbiological studies show that there is a possibility of PMI estimation in reference to presence of typical bacteria and fungi on cadaver or in soil beneath. Microbiome after death (thanatomicrobiome) changes and depends on time since death, temperature, seasons and environment-if human remains are covered, buried, placed in ice or left on the surface. To enlarge current knowledge, some of studies are conducted on animal models with further comparison thanatomicrobiome of different animals-pig, rats-to human cadaver thanatomicrobiome. This study collects different branches of thanatomicrobiome studies as a review to summarize current knowledge.

1. Introduction. 2. Living host microbiome and mycobiome. 3. Diseases-related differences. 4. Thanatomicrobiome – human cadavers studies. 5. Fungi presence – thanatomycobiome. 6. Thanatomicrobiome of frozen cadavers. 7. Soil microbial communities changes. 8. Seasons related microbial changes. 9. Thanatomicrobiome and entomology correlation. 10. Conclusions
“Food-Omics” Applications In The Food Metagenom Profiling
Authors: Juszczuk-Kubiak Edyta , Greguła-Kania Monika , Sokołowska Barbara
Published: March 2021

Modern research in food science and nutrition is transferring from classical methodologies to advanced molecular strategies in which next-generation sequencing (NGS) technology plays a crucial role. In this context, Foodomics has been recently defined as a new and global field using advanced “omics” technologies in food analysis. In recent years, “food-omics” technologies are widely applicated in food microbiology to identify, quantify and to track food microbial consortia in the food chain, as well as in the food safety and quality assessment. Metagenomics, referred to as community genomics is a sequence-based analysis of the collective genomes of microorganisms present in a given environment. This rapidly developing technique has provided new knowledge about taxonomic diversity and the dynamics of microbial communities at the genus, species and even strain level. An comprehensive metagenomic approach has proven to be a powerful tool in profiling the microbial ecology of complex ecosystems such as fermented foods. Currently, research focuses on understanding and controlling the fermentation process to ensure the consistent sensory properties of food products, increase safety and reduce food spoilage. The goal of this review is to provide an overview of the latest achievements of the “food-omics” technologies applied to biodiversity and functionality of food microflora, food safety and quality control. Furthermore, we discuss current challenges and future applications of “food-omics” technologies in the food industry.

1. Introduction. 2. Methodologies and technologies in the field of food-omics. 3. Application of “food-omics” technology in food analysis. 3.1. Metagenomics as a tool for monitoring the fermentation process. 3.2. Monitoring food storage conditions. 3.3. Food safety monitoring. 4. Summary
What Is at Stake in the Narrative of the Guests of Philosophical Practice?
Authors: Lindseth Anders
Published: March 2021

U dijalogu filozofijske prakse, filozof se neprekidno mora pitati o tome što je na djelu u pripovijestima gosta. O čemu su zapravo njihove priče? Posebna je, respondibilna pozornost potrebna u takvim dijalozima. Ovaj je rad pokušaj da se razjasni razlika između filozofijskog dijaloga i drugih dijaloga, kao što su svakodnevni dijalog i dijalozi s ekspertima, naročito profesionalnom pomoći. Filozofijska praksa razumije se kao posvećena tumačenju gostove poruke kao samokomunikacije, dok se izvan prostora prakse uobičajeno iskušava kao oblik obraćanja ili informacije. Etični je to izazov da filozofijski praktičar može otvoriti prostor pozornosti u dijalogu u kojem se samokomunikacija gosta može sagledati iznova i omogućiti novu orijentaciju u životu. Filozofijska praksa smjera k oslobađanju takve samokomunikacije od diskursa i k njenom lociranju u prirodi i slobodi.
Supervised learning of few dirty bosons with variable particle number
Authors: Mujal Pere , Martínez Miguel Àlex , Polls Artur , Juliá-Díaz Bruno , Pilati Sebastiano
Published: March 2021

We investigate the supervised machine learning of few interacting bosons in optical speckle disorder
via artificial neural networks. The learning curve shows an approximately universal
power-law scaling for different particle numbers and for different
interaction strengths. We introduce a network architecture that can be trained and tested on heterogeneous datasets
including different particle numbers.
This network provides accurate predictions for all system sizes included in the training set
and, by design, is suitable to attempt extrapolations to (computationally challenging) larger sizes.
Notably, a novel transfer-learning strategy is implemented, whereby the learning of the larger systems is substantially accelerated and made consistently accurate by including in the training set many small-size instances.
6-GINGEROL AND PHYSICOCHEMICAL PROPERTIES AS MONITORING PARAMETER FOR A NATURAL GROWTH PROMOTER NBIOTIC™ PREMIX DURING FEED PELLETIZATION STRESS
Authors:   R&D Centre, Ayurvet Limited, Village Katha, P.O. Baddi - 173205, District Solan, Himachal Pradesh, India., Kotagiri Ravikanth , Sharma Anirudh ,   R&D Centre, Ayurvet Limited, Village Katha, P.O. Baddi - 173205, District Solan, Himachal Pradesh, India., Ranjan Lal Uma ,   R&D Centre, Ayurvet Limited, Village Katha, P.O. Baddi - 173205, District Solan, Himachal Pradesh, India., Lata Pushap ,   R&D Centre, Ayurvet Limited, Village Katha, P.O. Baddi - 173205, District Solan, Himachal Pradesh, India., Thakur Deepak ,   R&D Centre, Ayurvet Limited, Village Katha, P.O. Baddi - 173205, District Solan, Himachal Pradesh, India.
Published: March 2021

Background: Feed is an important input for poultry and swine production, representing 50Ã¢Â€Â“70% of the total production costs. Feed processing provides an opportunity to improve poultry and swine performance. Herbal gut function modulators are used in poultry and swine feeds to improve nutrient utilization and efficiencies of biomass production. NbioticÃ¢Â„Â¢ Premix is a phytoformulation of AYURVET LIMITED, INDIA used in poultry and swine as a natural growth promoter (NGP) to effectively replace antibiotic growth promoters (AGP). Pelletization used to prevent wastage of feed, reduce bulk and improve digestibility and palatability. In present work we have assessed the stability of the NbioticÃ¢Â„Â¢ Premix herbal formulation under different pelletization thermal stress conditions. Methods: Formulation was kept under controlled temperature (90oC) and moisture (2.0 % w/w) for different time intervals (0, 5, 10 minutes). Chromatographic techniques (HPLC and HPTLC) and physicochemical properties were used to monitor the formulations stability. NbioticÃ¢Â„Â¢ Premix was stable at all the experimental investigation of pelletization thermal stress. Results: No significant change in the 6-gingerol content (250.0 ppm (Ã‚Â± 2.0 % at RT 10.05 minutes) and difference between peak areas and the retention factor (RF) values for the control samples and various thermal stress conditioned samples were observed. A comprehensive study of HPLC and HPTLC measurements have been applied for assessing the stability of NbioticÃ¢Â„Â¢ Premix. Developed methods (HPLC & HPTLC) were found to be rapid, sensitive and reliable in determining its stability. As evident, NbioticÃ¢Â„Â¢ Premix can undergo pelletization process without any degradation. In conclusion, present study will help towards developing appropriate stability monitoring parameters for herbal products which is a major challenge in the nutraceutical industry in current scenario.
Influence of common factors on vehicle bridge coupling vibration
Authors: Wen Jinsheng , Wu Tao , Ni Zhijun , Zhang Liangliang
Published: March 2021

As road and bridge construction industry becomes more prosperous, the vehicle’s speed and load capacity increase significantly. This paper aims at the problem of vehicle-bridge coupling vibration of highway bridges. In this paper, based on the basic theory of vehicle-bridge coupled vibration, the differential equation of vehicle-bridge coupled system is obtained. The mode decomposition method is adopted to transform the system differential equation into a matrix form. The second-order development function based on the built-in function was written by the principle of Runge-Kutta method, and the second-order time-varying differential equation group was solved. Taking the simply supported beam as an example, this paper studies the dynamic characteristics of bridge and vehicle under different speed and mass.
Analisa Pengaruh Persepsi Kualitas dan Harga Terhadap Minat Beli (Case Study Integrated home protection)
Authors:   School of Business and Economics Universitas Prasetiya MulyaJL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430 Indonesia, Roony Criest , Priambodo Dimas Dwi ,   School of Business and Economics Universitas Prasetiya MulyaJL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430 Indonesia, Candraditya A Habsari ,   School of Business and Economics Universitas Prasetiya MulyaJL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430 Indonesia, Reinastya A Kukie ,   School of Business and Economics Universitas Prasetiya MulyaJL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430 Indonesia, Hestiyani Medikatama ,   School of Business and Economics Universitas Prasetiya MulyaJL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430 Indonesia
Published: March 2021

In order to compete in the midst of a growing business in Indonesia, a product or service provider needs to understand many factors of consumer behavior. Among others there are factors that influence the purchase intention from the consumer side so that business can grow positively and sustain. This journal aims to explain variable of perceived quality and variable of price that affect the purchase intention variables in new products and services offered by Integrated home protection. The results of this study shows perceived quality and prices significantly affect purchase intention.