bluuebunny/crossref_metadata_2025 huggingface dataset:
PERBANDINGAN DAYA ANTIBAKTERI KOMBINASI EKSTRAK Eichhornia crassipes DAN Pistia stratiotes TERHADAP Salmonella typhi DAN Pseudomonas aeruginosa
Authors: Azhari Nazla Puteri , Budiarti Lia Yulia , Kaidah Siti
Published: December 2023

E.crassipes dan P.stratiotes mengandung senyawa antibakteri sehingga dapat dikembangkan sebagai disinfektan alternatif untuk pencegahan S.typhi dan P.aeruginosa melalui lingkungan dan peralatan yang kurang hygienis. Penelitian ini bertujuan membandingkan nilai koefisien fenol dan jumlah koloni S.typhi dan P.aeruginosa pada perlakuan kombinasi ekstrak E.crassipes dan P.stratiotes. (Ec+Ps), diperoleh nilai KF ekstrak Ec+Ps pada S.typhi=1,0333 dan pada P.aeruginosa=1,0333, nilai KF klorin 0,0002% pada S.typhi=1,0667 dan pada P.aeruginosa=1,2758. Kombinasi ekstrak Ec+Ps 25%,50%,75%,100% (ratio 1:1) memperlihatkan efek berbeda bermakna terhadap jumlah koloni bakteri uji. Kombinasi ekstrak Ec100%+Ps100% menghasilkan efek paling baik (p<0.05) terhadap jumlah koloni P.aeruginosa 21 CFU/ml daripada jumlah S.typhi 35 CFU/ml. Simpulannya, kombinasi ekstrak Ec+Ps memiliki daya antibakteri yang berbeda terhadap P.aeruginosa dibandingkan terhadap S.typhi.
Association Of Gestational Age And Birth Weight With Neonatal Sepsis In Ulin Hospital Banjarmasin
Authors: Andayani Pudji , Salim Monica Anggriana , Halim Pricilia Gunawan , Yunanto Ari
Published: December 2023

Indonesia is ranked 7th in the country with the highest neonatal mortality rate in the world, respectively 60.000 neonatal deaths per year. Neonatal sepsis in one of the major causes of neonatal death. The aim of this study is to find the association of gestational age and birth weight with the incidence of neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021. This study is a retrospective study with a cross sectional approach at Neonatal Ward, Ulin Hospital Banjarmasin, South Borneo, January to December 2021. The total sample was 200 infants consisting of 100 healthy infants and 100 sepsis infants. The source of gestational age, birth weight, and diagnosis data were taken through patient medical records. The mean gestational age of healthy infant group was 38,45 weeks (all infants were at term) while in septic infant group was 33,59 weeks (70%preterm, 28%at-term, and 2%post-term). The average birth weight of healthy infant group was 3021.24 grams (all infants were normal birth weight) while in septic infant group was 2003,59 grams (25%normal birth weight, 40%low birth weight, 25%very low birth weight, and 10%extremely low birth weight). There were an association of gestational age and birth weight with neonatal sepsis, confidential rate was 95%. (p<0,000 and p<0,000). There were an association of gestational age and birth weight with neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021.
The Effect of Wetland Geography on the Prevalence of Diabetes Mellitus in South Kalimantan
Authors: Fajari Nanang Miftah , Nur’amin Hendra Wana
Published: December 2023

Diabetes mellitus (DM) is a high-burden disease in Indonesia especially in South Kalimantan Province. South Kalimantan province lies in mostly wetlands areas. Identification of risk factors related to DM is necessary to prevent the disease. We conducted this study to assess the prevalence of DM in the South Kalimantan people, the impact of a wetlands area on DM prevalence, and other significant risk factors. A cross-sectional study approach was used to identify significant risk factors. We used adjusted multiple logistic regression to assess the association between risk factors and DM prevalence. There were 4612 subjects more than 18 years old in this study with 6.5% of them diagnosed as DM. Most of the subjects live in wetlands area (79.1%) and most of them >40 years old. Several important risk factors associated with DM were identified. Subjects in wetlands have a lower risk of DM compared to non-wetlands area (OR 0.73, CI 95%; 0.43-0.71, p<0.001). Age >40 years old increase the risk of DM (OR 2.24, CI 95 % 1.61-3.10, p<0.001), hypertension (OR 1.65, CI 95% 1.23-2.21, p<0,001), waist circumference >90 cm (OR 2.12, CI 95%. p<0.001), cholesterol level (>200 mg/dl) with DM prevalence (OR 1.38, CI 95% 1.02-1.87, p<0.04) and family history of DM (OR 10.28, CI 95% 7.67-13.76, p<0.001). This study found that wetlands areas may reduce the DM prevalence and other risk factors may increase the prevalence of DM. Further research is necessary to establish the relationship between wetlands area and DM.
The Association between Coping Mechanisms and Depression in Patients with Chronic Kidney Disease Undergoing Hemodialysis at Dr. Moewardi Hospital Surakarta
Authors: Zweiryadinda Wim , Oktaviyantini Tri , Kusuma Wijaya
Published: December 2023

Patients with chronic kidney disease (CKD) undergoing routine hemodialysis (HD) may experience psychiatric comorbidities like depression. The coping mechanism is thought to be associated with the emergence of depression in patients with CKD. This cross-sectional study examines the association between coping mechanisms and depression in CKD patients undergoing routine HD therapy at Dr. Moewardi Hospital, Surakarta. Brief COPE and Hospital Anxiety and Depression Scale (HADS) questionnaire were used as study instruments. The result showed that 29 (78.38%) research subjects used adaptive coping, while 8 (21.62%) used maladaptive coping. There are 13 (35%) participants with mild depression. Spearman’s rank correlation showed a strong negative correlation between adaptive coping mechanisms and the severity of depression in CKD patients undergoing hemodialysis (r=-0,655; p<0,01)
Description of Social Media Use and Self-Esteem of Adolescents in Makassar City
Authors: Rahman Framita , Jane Brigita Sri , Ngandoh Mutiara Cyesa Prasasti , Saputri Wiwi , Tuhelelu Puspa Akhlakul Karima
Published: December 2023

Adolescence is a crucial period of time and very challenging period. There is an increase concern on how social media use and mental health of teenagers. In Makassar City, there is a high number of mental health in adolescence yet still rare research has been conducted to investigates about social media use and self-esteem on teenagers. The aim of this study is to give a description on how adolescence behaviour on social media use and their level of self-esteem. This research uses a quantitative study with descriptive study design. The participant was selected based on some inclusion criteria such as teenagers’ age 16-18 years old, able to speak Bahasa, stay in Makassar City and willingly to become participant. The participant was determined by using non-probability sampling using convenience sampling method. There are 118 participants on this research. Three types of instruments were used; demography questionnaire, intensity of social media use and Rosenberg Self-Esteem Scale. From 118 participants, 19 were male and 99 were female. There are 42 respondents spend more than 6 hours on social media, and 54 respondents spend 2-6 hours on social media per day. Most of the respondents use their social media for see feed (20%), give like (14%), stalking (9%), news sharing (9%) and give comment (6%). Most of the respondents have high social media use (70 respondents) and low self-esteem (66 respondents). Social media use is quite high among teenagers in Makassar City and the self-esteem is mostly low. Thus, it is important to investigate the relationship of social media use and self-esteem so that it can give a comprehensive understanding on adolescence’s mental health and wellbeing in Makassar City
The Risk of Adverse Drug-Drug Interactions for Stable Angina Pectoris Patients with Heart Failure Complication Prescribed Polypharmacy
Authors: Fadillah Ahmad Aldi , Bakhriansyah Mohammad , Yustikasari Intan , Nurikhwan Pandji Winata , Adiputro Dwi Laksono
Published: December 2023

Stable angina pectoris (SAP) is an imbalance that occurs when myocardial oxygen need increases disproportionally, causing complaints of chest pain. Uncontrolled SAP can lead to a complication of heart failure (HF). Polypharmacy treatment frequently given to SAP patients with HF complications can be potentially detrimental for them. This study aims to determine the risk of adverse drug-drug interactions in SAP patients with HF complications prescribed polypharmacy. This was an analytic observational study with a cross-sectional approach using retrospective data from medical record data from 2020-2021 among hospitalized patients in cardiology ward Ulin General Hospital, Banjarmasin. Potential drug-drug interactions were determined using the Lexicomp tool from the UpToDate® site. Prevalence Odds Ratio (POR) and 95% Confidence Interval (95%CI) were determined using the Logistic Regression test at the 95% level of confidence. Twenty-four SAP patients with HF were recruited. According to its potential interactions, the most interactions were under category C (82.6%), followed by category B (11.3%) and category D (6.0%). Based on its level of severity, the most common was moderate (77.4%), followed by minor (13.0%) and major (9.5%). SAP patients with HF who were not prescribed polypharmacy had a lower risk of adverse drug-drug interactions by 64.7% compared to polypharmacy users, although it was not statistically difference (crude POR 0.353, 95% CI; 0.360-3.421; p-value = 0.369). This study shows that there is a tendency of lower risk of adverse drug-drug interactions in SAP patients with HF complication prescribed polypharmacy compared to those without polypharmacy, but the association is not statistically significant.
Home Sanitation and Clean Water Facilities in Stunting Cases at the Lampihong Health Center Area, Balangan
Authors: Heriyani Farida , Farida Ainun , Ulfah Maria
Published: December 2023

Stunting is a condition of growth failure in children under five years old (toddlers) due to chronic malnutrition and recurrent infections, especially in the first 1,000 days of life. One of the indirect causes is the availability of clean water and poor sanitation. Lampihong Community Health Center Balangan Regency is one of the areas with the highest stunting cases in South Kalimantan. This study aims to analyze the relationship between home sanitation and clean water facilities with the incidence of stunting in the Lampihong Community Health Center, Balangan Regency. The research method is analytic observational with a case control approach. The research sample consisted of 30 mothers of stunted toddlers as the case group and 30 mothers of non-stunted toddlers as the control group. Data analysis used the chi square test at a 95% confidence level. The research results showed that the majority of stunted toddlers lived in houses with unhealthy water closet, wastewater disposal and waste management that did not meet the requirements. Most of the stunted and non-stunted toddlers use clean water that meets the requirements. The results show that there is a significant relationship between home sanitation that does not meet the requirements and the incidence of stunting in toddlers, but there is no significant relationship between clean water facilities and the incidence of stunting in toddlers in the Lampihong Health Center, Balangan Regency.
PENGARUH KETINGGIAN ENGINE STAND SEPEDA MOTOR TERHADAP NILAI KEKUATAN MATERIAL (TEGANGAN DAN DEFLEKSI)
Authors: Isworo Hajar , Khalil Muhammad , Syahyuniar Rusuminto , Syaief Adhiela Noer , Bela Persada Anggun Angkasa , Lingga Yulima Melsipa , Artika Kurnia Dwi , Fahrozi Ikhsan
Published: December 2023

Kegagalan material berakibat komponen otomotif bisa menjadi patah, selain itu dapat berakibat chassis suatu kendaraan menjadi megalami lendutan (defleksi).  Faktor yang mempengaruhi kegagalan adalah beban pada suatu komponen kendaraan. Tujuan dari penelitian ini adalah untuk menganalisa tegangan dan defleksi pada engine stand sepeda motor akibat pembebanan. Engine stand menggunakan variasi ketinggian 40 cm, 45 cm dan 50 cm dengan bantuan software Autodesk Inventor Professional 2019. Hasil penelitian menunjukkan ketinggian 40 cm adalah ukuran ketinggian yang paling baik, karena tegangan normal (Smax), tegangan geser Tx, dan defleksinya minimum, walaupun pada nilai tegangan shear stress Ty nya nilainya lebih tinggi dari ukuran lainnya, tetapi nilainya sangat kecil dibandingkan Tegangan yieldnya (0,6 MPa < 207 MPa ). Hal ini berdampak positif pada rangka engine stand karena tidak terjadi deformasi plastis (rangka tidak akan patah). Material failure can cause automotive components to break, besides that it can cause a vehicle's chassis to experience deflection (deflection). Factors that affect failure is the load on a vehicle component . The purpose of this research is to analyze the stress and deflection on the motorcycle engine stand due to loading. The engine stand uses height variations of 40 cm, 45 cm and 50 cm with the help of Autodesk Inventor Professional 2019 software. The results showed that a height of 40 cm is the best measure of height, because the normal stress (Smax), shear stress Tx, and deflection are minimum, even though the shear stress value Ty is higher than the other sizes, the value is very small compared to the yield stress. (0.6 MPa < 207 MPa ). This has a positive impact on the engine stand frame because plastic deformation does not occur (the frame will not break).
Analysis of Grade X Physics Textbooks on the Basic Measurement Material from the Nature of Science Perspective
Authors: Huwaida Junita Insyirah , Saparini Saparini
Published: December 2023

Issues related to the quality of textbooks are often a topic of discussion in science. However, in various education systems, some textbooks have effectively incorporated the nature of science, while others are still lacking in this aspect. It is well-known that the nature of science serves as a crucial foundation that should be applied in science education, especially in physics. This is because the nature of science plays a role as the basis to guide a more holistic learning approach and an exploratory process in understanding knowledge about the natural world. Hence, a study was conducted to analyze physics textbooks to analyze the percentage of nature of science content and describe the proportion of nature of science aspects in high school physics textbooks. The research employed a mixed methods approach, combining qualitative and quantitative research. The quantitative research section involved the development of the theory, including observations and data collection for accuracy. The quantitative research portion explained how to obtain percentage data for the ten aspects of the nature of science under investigation. The study results showed that the textbook published by Grafindo, referred to as Book B, presented the most aspects of the nature of science compared to the other two textbooks. Quotations in Book B were presented explicitly, although some quotations were presented implicitly. Books A and C were found to be less inclusive of the nature of science aspects in the measurement material. The proportion of the appearance of the nature of science in Book A was 33%, in Book B, it was 53%, and in Book C, it was 27%. Overall, all three evaluated textbooks explicitly conveyed aspects of the nature of science. The implications of this research highlight the importance of incorporating the nature of science aspects in science learning materials to enhance understanding of the nature of science, as the nature of science is a complex concept and serves as a fundamental foundation for studying science.
Promoting Student Performance in STEM EDP Model on Climate Change Topics
Authors: Antika Vika Yulinda , Sulaeman Nurul Fitriyah , Hakim Abdul
Published: December 2023

Performance assessment is an authentic assessment that can be done with various kinds of assessments such as written assessments, observation, and assignments that can provide better feedback on performance and skills. Learning using STEM-EDP model is a learning that encourage students enggagement and in line with performance assessment. The topic in this lesson is climate change, that is relate with with global issue and suitable for STEM-EDP learning. The purpose of this study was to find out how the performance assesment category of class VII F students at Public Junior Highschool in Samarinda. This research uses a quantitative descriptive approach. The sample of this research was 31 students who were taken by cluster random sampling technique. The instruments used in this study were student worksheets and student performance rubrics. The results of the study obtained a process performance value of 78.3 and 78.6 which describes the process performance in the good category. The product performance values are 81.3 and 83.9 which fall into the very good category.The performance of students need to be promoted by more STEM EDP learning especially in junior high school level.
Motivos para adesão ao treinamento funcional entre praticantes regulares dessa modalidade
Authors: Heloisa Trabach Odelayne , Moraes Scardua Meneguci Thiago , Batista Costa Júnior Anibal
Published: December 2023

O treinamento funcional pode ser compreendido como um tipo de exercício físico que desenvolve as funções corporais de movimento de maneira equilibrada, ou seja, significa treinar com um propósito, seja para melhorar as ações motoras aplicadas ao cotidiano: como correr, agachar, puxar e etc, ou até mesmo no que tange a performance esportiva. A questão que orienta este estudo é: quais os motivos para adesão ao treinamento funcional entre praticantes regulares dessa modalidade de exercício físico, cujos objetivos são, compreender os principais motivos que estimulam as pessoas a praticarem o treinamento funcional; e comparar entre as faixas etárias os motivos da mesma. Para tanto, realizou-se uma pesquisa do tipo explicativa. Nesse sentido, foram selecionados 187 Centros de Treinamento (CT) no município de Vila Velha no Espírito Santo, o critério de seleção e escolha se deu a partir dos seguintes procedimentos: seleção dos espaços cadastrados no site do Conselho Federal de Educação Física (CONFEF); escolha daqueles que possuíam o termo Centro ou designação funcional, alcançando 45 resultados. Em seguida, entrou-se em contato via telefone e 18 aceitaram participar do estudo, sendo enviado um questionário estruturado aplicado presencialmente. Os resultados indicam que o grupo etário que se destaca na pesquisa à procura do treinamento é o de 50 anos ou mais, predominantemente mulheres, que praticam exercícios físicos de maneira orientada há mais de 6 anos. Constatou-se também que os entrevistados costumam praticar outros tipos de atividade, como a musculação em sua grande maioria, mas atividades aeróbias e modalidades esportivas também tem seu destaque. Os motivos que levam essas pessoas a aderirem à prática são variados, sendo a melhoria da qualidade de vida e promoção da saúde o principal motivo abordado pelos entrevistados. Em cima disso, foi apurado que muitos são os benefícios apontados pelos praticantes, tais como aumento da disposição, diminuição de gordura corporal, redução significativa de dores, entre outros. Por fim, a pesquisa aponta que 100% dos entrevistados recomendam ou recomendariam treinamento funcional às pessoas não praticantes, fato este que nos permite dizer que o programa pode ser eficaz para todo o tipo de público, a diferenciar seus objetivos.
Tempo de tela e prática de atividades físicas de adolescentes do Norte do Brasil
Authors: Carvalho da Silva Samuel , Araújo de Souza Alesandra , Lucena Joana Marcela Sales de
Published: December 2023

Objetivo: verificar a associação entre o comportamento sedentário e a prática de atividades físicas dos adolescentes. Métodos: estudo transversal, com amostragem por conglomerado de estágio único,           devido à quantidade de escolas públicas com ensino médio na cidade, todas foram consideradas  elegíveis para participação do estudo As variáveis coletadas foram: prática de atividade física na semana anterior (minutos/semana), como variáveis independentes o tempo de televisão, tempo de videogames, uso do celular, uso do computador (escolar e lazer), em minutos por semana. Foram obtidas tabelas com as frequências absolutas e percentuais e para as variáveis quantitativas, foram obtidas medidas de descrição (mínimo, média, mediana, máximo e desvio padrão). Os softwares utilizados na execução das análises estatísticas descritivas foram o Microsoft Office Excel e o Stata 13.0. Resultados: A  pesquisa foi realizada com um total de 162 estudantes, dentre esses 73 eram do sexo masculino, cerca de 60% da classe econômica C (classe média) e idade de 16 anos (±1,7). O tempo de atividade física foi de 1.346,6 minutos/semana, enquanto o temppo de televisão, computador para lazer e videogames foi de 690,56, 435 e 151 minutos/semana, respectivamente. A análise de regressão linear multivariada demonstrou que o  tempo usando o computador para lazer (β = 1,515, p <0,001) e para tarefas escolares (β = 0,147, p = 0,022) foram positivamente associados à atividade física na semana anterior. Conclusão: possivelmente o tempo de uso de computador para lazer e para estudos está associado a um perfil de escolar que pratica atividades físicas regularmente entre os adolescentes das escolas de Ensino Médio.
Avaliação psicométrica do fator latente de internalização da aparência ideal do Sociocultural Attitudes Towards Appearance Questionnaire-4 Revised (SATAQ-4R) em homens brasileiros cisgênero gays e bissexuais
Authors: Almeida Maurício , Gonçalves Santos Cleonaldo , De Oliveira Júnior Mauro Lúcio , Berbert de Carvalho Pedro Henrique
Published: December 2023

Objetivo: O presente estudo teve como objetivo avaliar as propriedades psicométricas (validade e confiabilidade) do fator latente de internalização da aparência ideal do Sociocultural Attitudes Towards Appearance Questionnaire-4 Revised (SATAQ-4R) em homens brasileiros cisgênero gays e bissexuais. Método: O instrumento foi aplicado em uma amostra de 1409 homens cisgênero gays e bissexuais, com idade entre 18 e 50 anos. Foi avaliada a estrutura fatorial da escala por meio de análise fatorial confirmatória (validade fatorial), bem como a validade convergente, por meio de associação entre os escores do fator latente de internalização da aparência ideal do SATAQ-4R e as variáveis de busca pela muscularidade, auto-objetificação, sinais e sintomas de transtornos alimentares e dismorfia muscular. A confiabilidade foi estimada pela análise de consistência interna e pela técnica teste-reteste, com um intervalo de duas semanas. Resultados: Observa-se que quando aplicado aos homens brasileiros cisgênero gays e bissexuais, o fator latente de internalização da aparência ideal do SATAQ-4R replicou sua estrutura original com três subescalas (Internalização – Magreza/Baixa gordura corporal, Internalização – Muscular, e Internalização – Atratividade geral) e oito itens, apresentando ótimos índices de ajustamento (χ²/gl = 0,62; CFI = 0,99; TLI = 0,99; SRMR = 0,01; e RMSEA = 0,00 [IC 95%: 0,00-0,01; p ≥ 0,05]). Foi observado também, uma adequada validade convergente, assim como adequada consistência interna e estabilidade teste-reteste, atestando a confiabilidade da versão brasileira do fator latente de internalização da aparência ideal do SATAQ-4R quando aplicado em homens brasileiros cisgênero gays e bissexuais. Conclusão: Conclui-se que o fator latente de internalização da aparência ideal do SATAQ-4R apresentou bons indicadores psicométricos de validade e confiabilidade em uma amostra de homens brasileiros cisgênero gays e bissexuais.
ENSINANDO MICROBIOLOGIA A PARTIR DA PEDAGOGIA HISTÓRICO-CRÍTICA: UM RELATO DE EXPERIÊNCIA
Authors: Barbosa Gabriel da Rocha , Morais Müller Brenner Freitas de , Guimarães Simone Sendin Moreira
Published: December 2023

O relato apresenta atividades de ensino de biologia desenvolvidas por licenciandos em Ciências Biológicas em um colégio estadual militarizado em Goiás. A atividade foi realizada durante a implementação do Novo Ensino Médio (NEM), especificamente no Itinerário Formativo "Além da visão: conhecendo o micromundo". Nesse contexto, o artigo objetiva discutir as bases teórico-metodológicas mobilizadas no planejamento e desenvolvimento de atividades executadas nas aulas do Itinerário Formativo (Micromundo). A Pedagogia Histórico-Crítica (PHC) e os Estatutos do Conhecimento Biológico fundamentaram nossas práticas de ensino. Os conteúdos de ensino da aula aqui relatada são: "vírus", "microrganismos" e "classificação biológica". As imposições político-curriculares oriundas do NEM foram consideradas em nossas análises e discussões. Apesar do número reduzido de aulas, o contato com a escola lançou o desafio de atuar, em um contexto educacional em que as imposições político curriculares se constituem enquanto impasses e limitações à autonomia docente, ainda mais se levarmos em consideração que seus princípios e fundamentos são praticamente antagônicos aos da PHC. Finalmente, por esse relato reflexivo entendemos que o estágio se configurou enquanto um espaço contra hegemônico, que se insere na luta por uma educação pública de qualidade ao formar docentes a partir da PHC.
Akuntansi yang Bagaimana yang Mampu Meredam Sifat Materialistik?
Authors: Lestari Melati Indah , Septyan Krisno
Published: December 2023

The discovery of materialistic phenomena among accounting students is a form of the bad reality of conventional accounting education. This study aims to find out how accounting can reduce these characteristics in accounting students. Research using qualitative methods using grounded theory Methods of data collection through interviews, observation, and literature study to produce a theory. The results of the study show that sharia accounting, which is oriented towards immaterial aspects such as love and spirituality, is finally able to bring selfawareness and reduce the materialistic nature that has been embedded previously. In order to make it happen, non-mainstream sharia accounting topics are needed, which address the developing field of sharia accounting but have not yet been accommodated by a professional association. Through the appointment of this topic, it is also proven that science is not selfish because it does not stop at students but also talks back to the surrounding environment. 
Characterizing the Burden of Occupational Chemical Exposures by Sociodemographic Groups in the United States, 2021
Authors: Stephan-Recaido Shelley C. , Peckham Trevor K. , Lavoué Jérôme , Baker Marissa G.
Published: December 2023

Objectives. To estimate the number and prevalence of workers in the United States exposed to chemical hazards available in the Canadian job-exposure matrix (CANJEM) database and examine exposure disparities across sociodemographic groups.

Methods. We merged US worker demographic data from the Current Population Survey with CANJEM to characterize the burden and sociodemographic distribution of 244 chemical exposures in the United States in 2021. An interactive version of the full data set is available online ( https://deohs.washington.edu/us-exposure-burden ).

Results. Of the chemical exposures examined, the most prevalent were cleaning and antimicrobial agents (14.7% of workforce estimated exposed), engine emissions (12.8%), organic solvents (12.1%), polycyclic aromatic hydrocarbons (10.1%), and diesel engine emissions (8.3%). Racial and ethnic minoritized groups, persons with lower educational attainment, foreign-born noncitizens, and males were generally overrepresented in exposure to work-related chemical hazards.

Conclusions. In the United States, marginalized sociodemographic groups are estimated to experience an inequitable burden to many chemical exposures because of occupational segregation. Data from this analysis can inform occupational and public health research, policy, and interventions aimed at reducing the burden of disease and health inequities in the United States. (Am J Public Health. 2024;114(1):57–67. https://doi.org/10.2105/AJPH.2023.307461 )
A Physics-Informed Spatial-Temporal Neural Network for Reservoir Simulation and Uncertainty Quantification
Authors: Bi Jianfei , Li Jing , Wu Keliu , Chen Zhangxin , Chen Shengnan , Jiang Liangliang , Feng Dong , Deng Peng
Published: December 2023

Surrogate models play a vital role in reducing computational complexity and time burden for reservoir simulations. However, traditional surrogate models suffer from limitations in autonomous temporal information learning and restrictions in generalization potential, which is due to a lack of integration with physical knowledge. In response to these challenges, a physics-informed spatial-temporal neural network (PI-STNN) is proposed in this work, which incorporates flow theory into the loss function and uniquely integrates a deep convolutional encoder-decoder (DCED) with a convolutional long short-term memory (ConvLSTM) network. To demonstrate the robustness and generalization capabilities of the PI-STNN model, its performance was compared against both a purely data-driven model with the same neural network architecture and the renowned Fourier neural operator (FNO) in a comprehensive analysis. Besides, by adopting a transfer learning strategy, the trained PI-STNN model was adapted to the fractured flow fields to investigate the impact of natural fractures on its prediction accuracy. The results indicate that the PI-STNN not only excels in comparison with the purely data-driven model but also demonstrates a competitive edge over the FNO in reservoir simulation. Especially in strongly heterogeneous flow fields with fractures, the PI-STNN can still maintain high prediction accuracy. Building on this prediction accuracy, the PI-STNN model further offers a distinct advantage in efficiently performing uncertainty quantification, enabling rapid and comprehensive analysis of investment decisions in oil and gas development.
Revolutionizing business intelligence: Pioneering an enhanced adoption Framework through the Technology-Organization-Environment Paradigm
Authors: Subramaniam Radhakrishnan , Palakkeel Prashobhan , Arunmozhi Manimuthu
Published: December 2023

In today's dynamic and challenging business landscape, organizations encounter numerous obstacles that impede efficient operations. To surmount these challenges, organizations must adopt novel strategies, with Business Intelligence (BI) emerging as a favored approach. However, BI implementation is underpinned by diverse frameworks, causing uncertainty in identifying the driving forces behind organizational adoption. This research addresses this gap by introducing the Organizational, Complex, Knowledge-based Technological, User Experience, Economic, Environmental, and Social (OCKTUEES) framework. This framework encompasses eight pivotal factors that influence the adoption of BI within organizations. The proposed framework was validated through data analysis utilizing Structural Equation Modeling. The findings underscore the prominence of Perception and User Experience, Technology, Social Dynamics, Economic Viability, and Environmental Considerations as the top five influential drivers among the eight factors investigated. Diverging from existing frameworks like Technology-Organization-Environment (TOE), Model of Adoption (MOA), Diffusion of Innovation (DOI), and Resource-Based View (RBV), the OCKTUEES framework offers a more comprehensive array of constructs and meticulously reorganized variables. This paper not only furnishes organizations with a fresh framework replete with invaluable drivers but also furnishes a focal point as they embark on their business intelligence or any technology adoption journey.
Patterns in Domestic Injuries and how COVID-19 Lockdown Measures Changed Their Incidence in Mexico
Authors: García-González Gabriel , Muñoz-Maldonado Gerardo Enrique
Published: December 2023

Domestic accidents occur worldwide. From small burns and bruises to significant wounds and injuries from dangerous falls, not all of them reach clinical care; so to measure the toll of these hardships on society, we surveyed three major cities in Mexico to better understand the problem and how coronavirus disease 2019 (COVID-19) lockdown measures changed the incidence rate.
We conducted an analytical cross-sectional study using Microsoft Forms, with a digital survey distributed among the Mexican population from October 2021 to November 2021, during lockdown. The incidence of all injuries surveyed increasedduring the first year of the COVID-19 pandemic. A comparison of the time spent inside the house before and during the pandemic showed that only burns increased. The number of wounds and musculoskeletal injuries decreased as people spent more time at home. Women were shown to be the most vulnerable group.
This study offers an unprecedented perspective on home-related trauma, as past literature has mainly examined trauma injuries treated in hospitals. The types of wounds have morphed depending on the percentage of time spent in the house, which has undergone a remarkable transformation since the lockdown was enacted.
A prospective study of multimodal cocktail intercostal injection for chest pain relief after costal cartilage harvest for ear reconstruction
Authors: Jiang Dongwen , Dong Wenfang , Shang Qiaoli , Ma Chenhao , He Leren , Feng Yanjun
Published: December 2023

Chest pain is one of the most common complaints after costal cartilage harvest.The present study aimed to compare the effectiveness of intraoperative area local injection after costal cartilage harvest when mixed drugs or ropivacaine plus analgesic pump is used, as measured by visual analogue scale (VAS) scores, rescue analgesic consumption, postoperative movement steps, and related complications. Eligible microtia patients who underwent costal cartilage harvest during ear reconstruction were randomly assigned to either a mixed drugs injection group (mixed drugs group) or ropivacaine plus analgesic pump group (analgesic pump group).The VAS scores in the mixed drugs group were significantly lower than those in the analgesic pump group at rest (p < 0.05) and the VAS scores in the mixed drugs group were significantly lower than those in the analgesic pump group during coughing (p < 0.05) before 96h after surgery. Rescue analgesic consumption and rate of complications were significantly lower in the mixed drugs group compared with the analgesic pump group (all p<0.05). Postoperative mobility of patients was significantly higher in the mixed drugs group compared with the analgesic pump group(p < 0.05).In conclusion, compared with ropivacaine plus analgesic pump, local injection of mixed drugs reduced chest pain after costal cartilage harvest for microtia ear reconstruction with less rescue analgesic consumption and complications, improved the postoperative movement steps of patients.
The influence of loose layer water cut-off curtain on the slope stability of open-pit coal mines
Authors: Wang Hai
Published: December 2023

Water-rich open-pit mines in China face the problems of large water inflow, slope reinforcement difficulties and high mining risks. The construction of a water cut-off curtain to control groundwater in the loose layer of open-pit mines can effectively reduce the amount of water drainage, thus solving the problem of flooding in open-pit mines. However, the rise of the water level outside the curtain and the change in the geotechnical properties of the slope will affect the stability and safety of the slope of the open-pit mine. A computational model was constructed, and the limit equilibrium method and numerical simulation method were used for calculation and analysis to study and analyse the influence law of the water cut-off curtain of the loose layer on the stability of the slope. The research results show that under the effect of the water cut-off curtain, the water level on the outside of the cut-off curtain in the loose layer of the open-pit mine continues to rise, and the hydrostatic pressure and horizontal thrust of the slope body increase. As a result, the sliding force of the slope increases and the anti-skid force decreases, ultimately leading to a decrease in the slope stability coefficient of the open-pit. Assuming that the water level outside the curtain remains unchanged, if the construction position of the curtain is moved outwards, the stability coefficient of the slope will increase; conversely, if the position of the curtain is moved inwards, the stability coefficient of the slope will decrease. The maximum shear stress on the slope increases as the water level outside the water curtain rises. The maximum shear stress is mainly concentrated at the toe of the slope of the first platform below the surface and at the interface between the curtain and the bottom of the Quaternary System. The water curtain can control the water table. The water cut-off curtain can control the groundwater level of the slope and maintain slope stability.
On-site biosignal amplification using a single high-spin conjugated polymer
Authors: Lei Ting , Ge Gao-Yang , Xu Jingcao , Wang Xin , Sun Wenxi , Yang Mo , Mei Zi , Deng Xin , Li Peiyun , Pan Xi , Li Jia , Wang Xue , Zhang Zhi , Lv Shi , Dai Xiao
Published: December 2023

On-site or in-sensor biosignal transduction and amplification can offer several benefits such as improved signal quality, reduced redundant data transmission, and enhanced system integration1,2. A promising candidate for this purpose is ambipolar organic electrochemical transistors (OECTs) due to their favorable attributes, including high transconductance, low operation voltage, biocompatibility, and suitability for miniaturized amplifier design3,4. However, the performance of ambipolar OECT materials has remained limited, hindering their successful application in on-site biosignal amplification. Here, we propose to use high-spin, hydrophilic conjugated polymers and a computational screening approach to address this challenge. We designed a high-spin polymer, namely P(TII-2FT), which exhibits balanced and exceptionally high ambipolar OECT performance. The figure-of-merits achieved by the P(TII-2FT) devices surpass those of the current leading materials by 5 to 20 times, resulting in a remarkable voltage gain exceeding 800 V/V while maintaining a compact form factor. Based on the amplifier, we have successfully achieved on-site capture and amplification of various electrophysiological signals with greatly enhanced signal quality.
Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity
Authors: Spits Claudia , Krivec Nusa , de Deckersberg Edouard Couvreu , Lei Yingnan , Delbany Diana Al , Regin Marius , Verhulst Stefaan , Grunsven Leo van , Sermon Karen
Published: December 2023

Gains of 1q are a highly recurrent chromosomal abnormality in human pluripotent stem cells. In this work, we show that gains of 1q impact the differentiation capacity to derivates of the three germ layers, leading to miss-specification to cranial placode and non-neural ectoderm during neuroectoderm differentiation and by poorer expression of lineage specific markers in hepatoblasts and cardiac progenitors. Competition assays show that the cells retain their selective advantage during differentiation, which is mediated by a higher expression of MDM4, a gene located in the common region of gain. MDM4 drives the winner phenotype of the mutant cells in both the undifferentiated and differentiating state by reducing the cells’ sensitivity to DNA-damage through decreased p53-mediated apoptosis. Finally, we find that cell density in culture plays a key role in promoting the competitive advantage of the cells by increasing DNA damage.
Risk Factors Affecting Delay of Initiating Adjuvant Chemotherapy for Stage III Colorectal Cancer
Authors: Maeda Shingo , Ouchi Akira , Komori Koji , Kinoshita Takashi , Sato Yusuke , Muro Kei , Taniguchi Hiroya , Masuishi Toshiki , Ito Seiji , Abe Tetsuya , Shimizu Yasuhiro
Published: December 2023

Purpose
Delay in initiating adjuvant chemotherapy after curative resection of colorectal cancer has been reported to lead to poor prognosis, but few studies have looked at associated factors. This study aimed to identify risk factors for delay in initiating adjuvant chemotherapy.
Methods
Data from 200 consecutive patients who underwent curative resection and adjuvant chemotherapy for Stage III colorectal cancer between 2013 and 2018 were retrospectively collected and analyzed.
Results
Adjuvant chemotherapy was initiated more than eight weeks after surgery in 12.5% of patients (delay group). Compared to those with no delay (non-delay group), patients in the delay group had significantly higher rates of synchronous double cancers (2.3% vs. 16.0%, p = 0.001), preoperative bowel obstruction (10.3% vs. 32.0%, p = 0.003), laparotomy (56.0% vs. 80.0%, p = 0.02), concomitant resection (2.9% vs. 24.0%, p < 0.001), and postoperative complications (32.0% vs. 56.0%, p = 0.02), and a significantly longer length of hospital stay (median 12 vs. 30 days, p < 0.001). In multivariate analysis, synchronous double cancers (odds ratio 10.2, p = 0.008), preoperative bowel obstruction (odds ratio 4.6, p = 0.01), concomitant resection (odds ratio 5.2, p = 0.03), and postoperative complications of Clavien-Dindo grade ≥ IIIa (odds ratio 4.0, p = 0.03) were identified as independent risk factors for delay in initiating adjuvant chemotherapy.
Conclusion
Careful treatment planning is necessary for colorectal cancer patients with synchronous double cancers, preoperative bowel obstruction, and concomitant resection to avoid delay in initiating adjuvant chemotherapy.
The Effect of Dynamic Tape's Directional Support on Shoulder Fatigue and Pitching Performance in Amateur Baseball Players: A Randomized Crossover Trial
Authors: Huang Haw-Ming , Hsu Chih Yang , Hsieh I-Fan , Yang Po-Chieh , CHENG YU-HSUAN
Published: December 2023

This study aimed to assess the impact of applying Dynamic tape to the pitching shoulder on shoulder fatigue, delayed onset muscle soreness, and performance improvement. A randomized crossover study, with participants and assessors blinded, included 20 amateur adult baseball players without shoulder pain. Sham taping and Dynamic taping were alternated, using an internal rotation support taping method in both groups. Strengths and range of motion in bilateral shoulders were measured with a handheld dynamometer and protractor before and after each test. Percentage of strength decrease, pitch velocity, spin rate, and shoulder pain were recorded. The Dynamic tape group showed a significant reduction in internal rotation strength decline compared to the sham group (-1.4% vs. 7.0%, p = 0.03). However, no significant differences were observed in other strength declines, shoulder range of motion, pain, pitching velocity, or spin rate. Dynamic tape reduced direction-specific shoulder fatigue but did not significantly enhance pitching performance or prevent delayed onset muscle soreness.
Structure of a Rhs effector clade domain identifies new mechanistic insights into type VI secretion system toxin delivery.
Authors: McGowan Sheena , Hayes Brooke , Harper Marina , Venugopal Hariprasad , Lewis Jessica , Wright Amy , Steele Joel , Steer David , Schittenhelm Ralf , Boyce John
Published: December 2023

The type VI secretion system (T6SS) is a molecular machine utilised by many Gram-negative bacteria to deliver antibacterial toxins directly into adjacent bacteria, often providing a competitive advantage. Rearrangement hotspot (Rhs) effectors are known T6SS cargo effectors, but the precise delivery and activation of these toxins is poorly defined. We present the structure of a novel T6SS Rhs effector (Tse15) from the multidrug resistant nosocomial pathogen Acinetobacter baumannii. Tse15 forms a triple layered β-cocoon Rhs domain with an N-terminal α-helical clade domain and an unfolded C-terminal toxin domain located entirely inside the Rhs cage. We identify that Tse15 is cleaved into three domains, through two independent auto-cleavage events involving aspartyl protease activity for toxin self-cleavage and a nucleophilic glutamic acid for the cleavage of the N-terminal clade domain. Proteomic analyses showed that the N-terminal clade and toxin domains, but not the β-strand rich Rhs cage, are delivered outside of the cell, suggesting a novel mechanism for Rhs toxin delivery and activation. Our findings suggest that this delivery mechanism requires an interaction between the N-terminal clade and toxin domains, with the clade domain acting as the internal chaperone to mediate tethering of the toxin to the T6SS machinery. Conservation of the clade domain in other Gram-negative bacteria suggest this may be a common mechanism for T6SS toxin delivery.
Theoretical insights from adsorption of ofloxacin using Zn2SnO4/reduced graphene oxide composite
Authors: Castro Janevane , Oliveira Renato , Bezerra Lucas , Souza-Júnior José , Chaves Anderson , Correia Adriana , Monteiro Norberto
Published: December 2023

Emerging Contaminants (ECs), such as pesticides, steroid hormones, antibiotics growth accelerators, and inhibitors of pathogenic microorganisms, among others, have become an increasingly severe and worrying problem to ecosystems and human health, including the contamination of water bodies. Therefore, it is imperative to seek ways to measure and evaluate the current conditions of various environmental matrices so that urgent strategies can be planned and designed to mitigate the spread of these contaminants. Ofloxacin, a widely prescribed antibiotic, is resistant to biological degradation and promotes bacteria resistance, being considered environmentally maleficent. In this sense, this work arises to theoretically study the adsorption of ofloxacin (OFL) on two surfaces (zinc stannate (Zn2SnO4) and reduced graphene oxide (rGO)), considering that OFL is classified as a toxic organic EC and, therefore, it is imperative to develop analytical methodologies for their removal. Furthermore, all theoretical calculations were carried out in the CASTEP software using Density Functional Theory (DFT) and the GGA functional, obtaining results for adsorption energy, band structure and Total Density of States (TDOS). The results showed that adsorption occurs more effectively with Zn2SnO4 (1 0 0), with an adsorption energy of -21.03 eV, compared to -1.90 eV in the rGO surface (1 0 0), and that the metallic character of this compound did not change after OFL adsorption. However, the OFL-Zn2SnO4 complex had more states to be occupied. Furthermore, it was observed that the OFL-rGO complex presented a greater semiconductor character.
NeuroWorm: a Long-term Implantable Soft Microfibre for Multimodal Biosensing
Authors: Liu Zhiyuan , Xie Ruijie , Yu Qianhengyuan , Li Dong , Han Xu , Xu Xiaolong , Huang Jianping , Zhou Xiaomeng , Zhao Hang , Deng Xinping , Tian Qiong , Li Qingsong , Li Hanfei , Zheng Hairong , Li Guanglin , Zhu Meifang , Yan Wei , Han Fei , Xu Tiantian
Published: December 2023

Long-term implantable bioelectronics can efficiently evaluate the function of the nervous system and serve as effective human-machine interfaces. Here, inspired by earthworms, we introduce NeuroWorm, a soft and stretchable fibre sensor for bio-signal monitoring. Our approach involves rolling to transform 2D bioelectronic devices into 1D NeuroWorm, resulting in a soft, multifunctional microfibre housing over 60 longitudinally-distributed electrodes for bio-electric and -mechanical monitoring. It can be implanted in muscle with tiny incision for 8-month bio-electrical monitoring in rats. Importantly, after 13-month implantation, the fibroblast encapsulation around the fibre is negligible. Moreover, it can wander inside a brain under magnetic field. This strategy not only facilitates the development of multi-channel and multi-functional soft and stretchable fibre-shaped NeuroWorm sensors but also offers a platform for unprecedently long-term minimally-invasive implantable bioelectronics.