bluuebunny/crossref_metadata_2025 huggingface dataset:
Pulmonary Function, Computed Tomography Lung Abnormalities, and Small Airway Disease after COVID-19: 3-, 6-, and 9-Month Follow-Up
Authors: Kłos Krzysztof , Jaskóła-Polkowska Dominika , Plewka-Barcik Katarzyna , Rożyńska Renata , Pietruszka-Wałęka Ewa , Żabicka Magdalena , Kania-Pudło Marta , Maliborski Artur , Plicht Katarzyna , Angielski Grzegorz , Wojtyszek Andrzej , Jahnz-Różyk Karina , Chciałowski Andrzej
Published: May 2024

Background/Objectives: Coronavirus disease 2019 (COVID-19) course may differ among individuals—in particular, those with comorbidities may have severe pneumonia, requiring oxygen supplementation or mechanical ventilation. Post-COVID-19 long-term structural changes in imaging studies can contribute to persistent respiratory disturbance. This study aimed to investigate COVID-19 sequels affecting the possibility of persistent structural lung tissue abnormalities and their influence on the respiratory function of peripheral airways and gas transfer. Methods: Patients were divided into two groups according to severity grades described by the World Health Organization. Among the 176 hospitalized patients were 154 patients with mask oxygen supplementation and 22 patients with high-flow nasal cannula (HFNC) or mechanical ventilation. All tests were performed at 3, 6, and 9 months post-hospitalization. Results: Patients in the severe/critical group had lower lung volumes in FVC, FVC%, FEV1, FEV1%, LC, TLC%, and DLCO% at three months post-hospitalization. At 6 and 9 months, neither group had significant FVC and FEV1 value improvements. The MEF 25–75 values were not significantly higher in the mild/moderate group than in the severe/critical group at three months. There were weak significant correlations between FVC and FEV1, MEF50, MEF 75, plethysmography TLC, disturbances in DLCO, and total CT abnormalities in the severe/critical group at three months. In a mild/moderate group, there was a significant negative correlation between the spirometry, plethysmography parameters, and CT lesions in all periods. Conclusions: Persistent respiratory symptoms post-COVID-19 can result from fibrotic lung parenchyma and post-infectious stenotic small airway changes not visible in CT, probably due to persistent inflammation.
Non-Invasive Ventilation Support during Hospitalization for SARS-CoV-2 and the Risk of Venous Thromboembolism
Authors: Siniscalchi Carmine , Ticinesi Andrea , Nouvenne Antonio , Guerra Angela , Parise Alberto , Finardi Lorenzo , Cerundolo Nicoletta , Prati Beatrice , Guida Loredana , Meschi Tiziana
Published: May 2024

Background/Objectives: Although SARS-CoV-2 infection is a significant risk factor for venous thromboembolism (VTE), data on the impact of the use of non-invasive ventilation support (NIVS) to mitigate the risk of VTE during hospitalization are scarce. Methods: Data for 1471 SARS-CoV-2 patients, hospitalized in a single hub during the first pandemic wave, were collected from clinical records, including symptom duration and type, information on lung abnormalities on chest computed tomography (CT), laboratory parameters and the use of NIVS. Determining VTE occurrence during hospital stays was the main endpoint. Results: Patients with VTE (1.8%) had an increased prevalence of obesity (26% vs. 11%), diabetes (41% vs. 21%), higher CHA2DS2VASC score (4, IQR 2–5 vs. 3, IQR 1–4, age- and sex-adjusted, p = 0.021) and cough (65% vs. 44%) and experienced significantly higher rates of NIVS (44% vs. 8%). Using a stepwise multivariate logistic regression model, the prevalence of electrocardiogram abnormalities (odds ratio (OR) 2.722, 95% confidence interval (CI) 1.039–7.133, p = 0.042), cough (OR 3.019, 95% CI 1.265–7.202, p = 0.013), CHA2DS2-VASC score > 3 (OR 3.404, 95% CI 1.362–8.513, p = 0.009) and the use of NIVS (OR 15.530, 95% CI 6.244–38.627, p < 0.001) were independently associated with a risk of VTE during hospitalization. NIVS remained an independent risk factor for VTE even after adjustment for the period of admission within the pandemic wave. Conclusions: Our study suggests that NIVS is a risk factor for VTE during hospitalization in SARS-CoV-2 patients. Future studies should assess the optimal prophylactic strategy against VTE in patients with a SARS-CoV-2 infection candidate to non-invasive ventilatory support.
Validation of a Prediction Model for Acute Kidney Injury after Cardiac Surgery in a Retrospective Asian Cohort
Authors: Tsai Pei-Hsin , Wang Jun-Sing , Shen Ching-Hui
Published: May 2024

Background: The incidence of postoperative acute kidney injury (AKI) is relatively high in some Asian regions. The objective of this study was to examine the performance of an AKI prediction model developed based on data from a White-dominant population in a retrospective Asian cohort of patients undergoing cardiovascular surgery. Methods: We retrospectively identified 549 patients who underwent elective major cardiovascular surgery (coronary artery bypass graft, valve surgery, and aorta surgery), and excluded those who underwent a percutaneous cardiovascular procedure. Patients with a baseline estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 were also excluded. AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) definition. Performance of the prediction model for AKI was expressed as area under the receiver operating characteristic curve (AUC). Results: The prediction model had a good predictive accuracy for postoperative AKI (all AUC > 0.92). The AUC of the prediction model in subgroups of age (<65 years and ≥65 years), sex (male and female), hypertension, and diabetes were all >0.85 (all p values < 0.001). Conclusions: The model could be used to predict postoperative AKI in Asian patients undergoing cardiovascular surgery with a baseline eGFR ≥ 60 mL/min/1.73 m2.
Comorbidities, Treatment and Survival Rates of Chronic Thromboembolic Pulmonary Hypertension in a Regional Centre
Authors: Bertici Razvan Adrian , Bertici Nicoleta Sorina , Ridichie Amalia , Fira-Mladinescu Ovidiu
Published: May 2024

Background/Objectives: Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by a multitude of underlying causes, treatment modalities and prognostic outcomes. Our aim was to evaluate the underlying causes, comorbidities and survival rates of CTEPH patients. Methods: A retrospective analysis was conducted regarding the evolution of CTEPH patients confirmed by right heart catheterization under treatment with specific vasodilator medication in our centre between 2008 and 2023. Results: We treated 14 CTEPH patients, 78.57% female, 52.79 ± 13.64 years at inclusion, representing 11.29% of our pulmonary arterial hypertension registry. Initially, the distribution of patients’ NYHA class was II-14.28%, III-71.42% and IV-14.28%. In total, 71.42% of these patients were technically operable due to the central location of the thrombus, but 42.85% presented severe comorbidities and 28.57% refused the surgery or it was financially inaccessible. Only four patients were operated on by pulmonary endarterectomy (PEA). Unfortunately, all the post-PEA patients had persistent pulmonary hypertension and had to continue vasodilator treatment. Overall, 64.28% of patients had monotherapy, 21.42% double therapy and 14.28% triple therapy. Regarding underlying causes and comorbidities, we found the following incidences: 78.57% chronic venous insufficiency, 42.85% obesity, 35.71% thyroid disease, hypertension and hyperuricemia, 21.42% thrombophilia and ischemic heart disease, 14.28% atrial fibrillation, vasculitis and lung disease, and 14.28% neoplastic history and diabetes. Seven patients died (50%), six of whom were unoperated and one of whom was lost (abandoned the program). The survival rates at 1, 3, 5 and 7 years for unoperated patients were 100%, 58.3%, 29.2% and 29.2% versus 100%, 75%, 75% and 75% in post-PEA patients. Conclusions: CTEPH, marked by delayed diagnosis, multiple comorbidities and limited intervention options, requires proactive screening and comprehensive multimodal therapies, including PEA, to improve survival rates.
Emerging Contributions of Pluripotent Stem Cells to Reproductive Technologies in Veterinary Medicine
Authors: de Castro Raiane Cristina Fratini , Buranello Tiago William , Recchia Kaiana , de Souza Aline Fernanda , Pieri Naira Caroline Godoy , Bressan Fabiana Fernandes
Published: May 2024

The generation of mature gametes and competent embryos in vitro from pluripotent stem cells has been successfully achieved in a few species, mainly in mice, with recent advances in humans and scarce preliminary reports in other domestic species. These biotechnologies are very attractive as they facilitate the understanding of developmental mechanisms and stages that are generally inaccessible during early embryogenesis, thus enabling advanced reproductive technologies and contributing to the generation of animals of high genetic merit in a short period. Studies on the production of in vitro embryos in pigs and cattle are currently used as study models for humans since they present more similar characteristics when compared to rodents in both the initial embryo development and adult life. This review discusses the most relevant biotechnologies used in veterinary medicine, focusing on the generation of germ-cell-like cells in vitro through the acquisition of totipotent status and the production of embryos in vitro from pluripotent stem cells, thus highlighting the main uses of pluripotent stem cells in livestock species and reproductive medicine.
Fracture Resistance of a Bone-Level Two-Piece Zirconia Oral Implant System—The Influence of Artificial Loading and Hydrothermal Aging
Authors: Kohal Ralf J. , Riesterer Ellen , Vach Kirstin , Patzelt Sebastian B. M. , Iveković Aljaž , Einfalt Lara , Kocjan Andraž , Hillebrecht Anna-Lena
Published: May 2024

Preclinical and clinical research on two-piece zirconia implants are warranted. Therefore, we evaluated the in vitro fracture resistance of such a zirconia oral implant system. The present study comprised 32 two-piece zirconia implants and abutments attached to the implants using a titanium (n = 16) or a zirconia abutment screw (n = 16). Both groups were subdivided (n = 8): group T-0 comprised implants with a titanium abutment screw and no artificial loading; group T-HL was the titanium screw group exposed to hydro-thermomechanical loading in a chewing simulator; group Z-0 was the zirconia abutment screw group with no artificial loading; and group Z-HL comprised the zirconia screw group with hydro-thermomechanical loading. Groups T-HL and Z-HL were loaded with 98 N and aged in 85 °C hot water for 107 chewing cycles. All samples were loaded to fracture. Kruskal–Wallis tests were executed to assess the loading/bending moment group differences. The significance level was established at a probability of 0.05. During the artificial loading, there was a single occurrence of an implant fracture. The mean fracture resistances measured in a universal testing machine were 749 N for group T-0, 828 N for group Z-0, 652 N for group T-HL, and 826 N for group Z-HL. The corresponding bending moments were as follows: group T-0, 411 Ncm; group Z-0, 452 Ncm; group T-HL, 356 Ncm; and group Z-HL, 456 Ncm. There were no statistically significant differences found between the experimental groups. Therefore, the conclusion was that loading and aging did not diminish the fracture resistance of the evaluated implant system.
Day-to-Night Street View Image Generation for 24-Hour Urban Scene Auditing Using Generative AI
Authors: Liu Zhiyi , Li Tingting , Ren Tianyi , Chen Da , Li Wenjing , Qiu Waishan
Published: May 2024

A smarter city should be a safer city. Nighttime safety in metropolitan areas has long been a global concern, particularly for large cities with diverse demographics and intricate urban forms, whose citizens are often threatened by higher street-level crime rates. However, due to the lack of night-time urban appearance data, prior studies based on street view imagery (SVI) rarely addressed the perceived night-time safety issue, which can generate important implications for crime prevention. This study hypothesizes that night-time SVI can be effectively generated from widely existing daytime SVIs using generative AI (GenAI). To test the hypothesis, this study first collects pairwise day-and-night SVIs across four cities diverged in urban landscapes to construct a comprehensive day-and-night SVI dataset. It then trains and validates a day-to-night (D2N) model with fine-tuned brightness adjustment, effectively transforming daytime SVIs to nighttime ones for distinct urban forms tailored for urban scene perception studies. Our findings indicate that: (1) the performance of D2N transformation varies significantly by urban-scape variations related to urban density; (2) the proportion of building and sky views are important determinants of transformation accuracy; (3) within prevailed models, CycleGAN maintains the consistency of D2N scene conversion, but requires abundant data. Pix2Pix achieves considerable accuracy when pairwise day–and–night-night SVIs are available and are sensitive to data quality. StableDiffusion yields high-quality images with expensive training costs. Therefore, CycleGAN is most effective in balancing the accuracy, data requirement, and cost. This study contributes to urban scene studies by constructing a first-of-its-kind D2N dataset consisting of pairwise day-and-night SVIs across various urban forms. The D2N generator will provide a cornerstone for future urban studies that heavily utilize SVIs to audit urban environments.
Vibration Characteristic Research of 100 m New Polar Exploration Cruise Based on Finite Element Modeling
Authors: Jiang Guohe , Yuan Yuhao , Guo Hao , Wu Gang , Liu Zhenzhen
Published: May 2024

Luxury cruise ships are high-end passenger ships with facilities on board for the leisure and entertainment of passengers, so the comfort of luxury cruise ships is a matter of great concern. In this paper, a finite element model of a new polar exploration cruise ship is established, and the wet modes of the whole ship are calculated using the virtual mass method and compared with the principal frequencies of the excitation forces to initially verify the rationality of the design of the structural vibration characteristics of the whole ship. The admittance matrix of the vibration velocity to excitation force was calculated by a frequency response analysis, and the vibration velocities at the stern plate and main engine foundations were tested during sailing. Then, the obtained propeller and main engine excitation forces were loaded into the finite element model; the vibration velocities of each compartment were calculated and compared with the compartment vibration velocity test values. The errors were within the engineering allowable range, verifying the accuracy of the excitation forces. The propeller and main engine excitation forces were loaded separately on the finite element model to calculate the vibration velocity of each cabin, and the contribution of the two excitation sources to the vibration velocity of each cabin was analyzed. It was found that the contribution of the excitation source to the cabin response was related to the relative position between the cabin and the excitation source. When the cabin was located in the cabin adjacent to or directly above a certain excitation source, the contribution of the excitation source to the cabin response was greater. When the cabin was farther away from both excitation sources, the contribution of the propeller excitation was greater. This provides a targeted reference for the preliminary vibration assessment and later vibration control of the new polar expedition cruise ship.
A Multi-Objective Scheduling Strategy for a Hybrid Energy System for Antarctic Coastal Research Stations
Authors: Zuo Guangyu , Dou Yinke , Wang Jin , Yang Bo , Kou Liwei
Published: May 2024

A large number of research stations have been established to provide members of Antarctic expeditions with logistical support. A previous study confirmed that the wind and solar energy resources of the Chinese Zhongshan Station, a coastal station located in an area of Lassmann Hills in East Antarctica, are highly synergetic and complementary. Considering the demand for a renewable energy power supply in Zhongshan Station, this paper introduces a hybrid energy system with wind–solar–diesel–battery co-generation used as a power supply scheme. Based on the 2015 climate data for Zhongshan Station, the wind–solar resources, conventional energy system, and annual diesel consumption of the station area were analyzed. The annual electrical load demand of each building in the station area was quantitatively expounded. Compared with the original power supply system, and combined with the analysis results of the thermal load and electrical load demands of the station, an objective function based on the requirements of economy, reliability, and environmental protection was presented. According to the constraint conditions of the heat energy and electrical energy load balance in the station area, a multi-objective scheduling strategy for the system was designed. Finally, the effects of this scheduling strategy were analyzed under three different application scenarios. The results indicated that the annual load demand was significantly lower than before the scheduling, and that a 50% reduction in diesel consumption could be achieved, demonstrating that the multi-objective scheduling strategy proposed in this paper could achieve optimal energy scheduling and management of the renewable hybrid energy system.
Relationship between Postoperative Complications and Ratio of Amount of Wetting Solution to Ideal Body Weight in Liposuction Procedures
Authors: Aktas Yildirim Serap , Dogan Lerzan , Sarikaya Zeynep Tugce , Gucyetmez Bulent , Demirtas Yener , Toraman Fevzi
Published: May 2024

Background: The use of wetting solutions (WSs) during high-volume liposuction is standard; however, the optimal amount of WS and its components and their effect on postoperative complications are unclear. We evaluated the effect of a WS and its components, calculated according to ideal body weight (IBW), on postoperative complications. Methods: High-volume liposuction with a WS containing 0.5 g of lidocaine and 0.5 mg of epinephrine in each liter was performed in 192 patients. Patients who received ≤90 mL/kg of WS were designated as group I and those who received >90 mL/kg of WS as group II. Postoperative complications and adverse events that occurred until discharge were recorded. Results: The mean total amount of epinephrine in the WS was significantly higher for group II (3.5 mg; range, 3.0–4.0 mg) than for group I (2.0 mg; range, 1.8–2.5 mg; p < 0.001), as was the mean total amount of lidocaine (3.5 g [range, 3.5–4.3 g] vs. 2.0 g [range, 1.8–2.5 g], respectively; p < 0.001). No major cardiac or pulmonary complications occurred in either group. Administration of >90 mL/kg of WS increased the median risk of postoperative nausea 5.3-fold (range, 1.8- to 15.6-fold), that of hypertension 4.9-fold (range, 1.1- to 17.7-fold), and that of hypothermia 4.2-fold (range, 1.1- to 18.5-fold). The two groups had similar postoperative pain scores and blood transfusion rates. Conclusions: The risks of postoperative nausea, vomiting, hypothermia, and hypertension may increase in patients who receive >90 mL/kg of WS calculated according to IBW during high-volume liposuction.
Denominal -ed Adjectives and Their Adjectival Status in English Morphology
Authors: Ishida Takashi
Published: May 2024

In the study of English denominal adjectives, scholarly attention has predominantly centred on those with Latinate suffixes (e.g., -al, -ary, and -ic/-ical), which are well-known as relational adjectives (RAdjs) and are extensively scrutinised in the existing literature. Conversely, those with English native suffixes (e.g., -en, -ern, -y, and -ed) have not undergone thorough examination to date. In the present study, I delve specifically into denominal adjectives with the suffix -ed (-ed Adjs), such as bearded, long-tailed, and shirt-sleeved. I present a novel basic picture of these adjectives, setting forth the following two central propositions: (i) -ed Adjs are a type of RAdj and (ii) undergo conversion to qualitative adjectives (QAdjs) (e.g., bearded man vs. bearded rock) akin to the better-known Latinate RAdjs (e.g., grammatical error vs. grammatical sentence). The analysis is conducted by examining suffixal etymology (i.e., Latinate or Germanic), suffixal properties (i.e., all-purpose or dedicated), and the driving factor for QAdj-forming conversion (i.e., the modal attribute true). These propositions and analyses collectively enrich our comprehensive understanding of the semantic and morphosyntactic properties of -ed Adjs within the realm of English morphology.
Analysis of Properties and Macroscopic Defects of Metallic Bars, Pipes, and Strands through the Spectrum of Low-Frequency Excitations
Authors: Mancini Matteo , Turchetta Bruno , Cirillo Matteo
Published: May 2024

It is demonstrated that the application of piezoelectric sensors to metallic bars and strands can enable determining the status of the integrity of these elements through the spectrum of their acoustic excitations. The voltage output of the piezo, secured to metal bars or strands, is fed to the input of a Fast Fourier Transform analyzer, which allows displaying the spectrum of the excitations from which information on the length, overall quality of the metal, and the presence of defects can be obtained. We show that the analysis, performed on several materials and strands of different lengths, could be useful for cases in which visible inspection and/or direct access to the entire body of the metallic elements is not possible. Applications of our study for testing metallic structures embedded in concrete foundations are reported for construction sites.
Inductive Heating of Ceramic Matrix Composites (CMC) for High-Temperature Applications
Authors: Hackert Alexander , Stiller Jonas H. M. , Winhard Johannes , Kotlan Václav , Nestler Daisy
Published: May 2024

The inductive heating of a CMC susceptor for industrial applications can generate very high process temperatures. Thus, the behavior of a silicon carbide-based matrix with carbon-fiber-reinforced carbon (C/C-SiC) as a susceptor is investigated. Specifically, the influence of fiber length and the distribution of carbon fibers in the composite were investigated to find out the best parameters for the most efficient heating. For a multi-factorial set of requirements with a combination of filling levels and fiber lengths, a theoretical correlation of the material structure can be used as part of a digital model. Multi-physical simulation was performed to study the behavior of an alternating magnetic field generated by an inducing coil. The simulation results were verified by practical tests. It is shown that the inductive heating of a C/C-SiC susceptor can reach very high temperatures in a particularly fast and efficient way without oxidizing if it is ensured that a silicon carbide-based matrix completely encloses the fibers.
Relationship between Ambient Temperature and Reasonable Heat Dissipation Coefficient of Mass Concrete Pouring Blocks
Authors: Zhang Jiaming , Zhang Hongshi , Zhao Yunpeng , Xu Wenqiang , Su Min , Ge Jinyu , Qiang Sheng
Published: May 2024

In engineering practice, similar surface insulation measures are typically applied to different parts of mass concrete surfaces. However, this can lead to cracking at the edges of the concrete surface or the wastage of insulation materials. In comparison to flat surfaces, the edges of mass concrete structures dissipate heat more rapidly, leading to more pronounced stress concentration phenomena. Therefore, reinforced insulation measures are necessary. To reduce energy consumption and enhance overall insulation effectiveness, it is essential to study the specific insulation requirements of both the flat surfaces and edges of concrete separately and implement targeted surface insulation measures. Taking the bridge abutment planned for pouring in Nanjing City as the research object, this study established a finite element model to explore the effects of different ambient temperatures and different surface heat dissipation coefficients on the early-age temperature and stress fields of different parts of the abutment’s surface. Based on simulation results, reasonable heat dissipation coefficients that meet the requirements for crack prevention on both the structure’s plane and edges under different ambient temperatures were obtained. The results indicate that under the same conditions, the reasonable heat dissipation coefficient at the edges was smaller than that on the flat surfaces, indicating the need for stronger insulation measures at the edges. Finally, mathematical models correlating ambient temperature with reasonable heat dissipation coefficients for the structure’s plane and edges at these temperatures were established, with high data correlation and determination coefficients (R2) of 0.95 and 0.92. The mathematical models were validated, and the results from finite element calculations were found to be consistent with those from the mathematical models, validating the accuracy of the mathematical models. The conclusions drawn can provide references for the insulation of similar engineering concrete planes and edges.
Maximum Packing of λ-Fold Complete 3-Uniform Hypergraph with a Special Tetrahedron
Authors: Zhu Yuzhe , Zhao Hongtao
Published: May 2024

Let Kv(3)=(V,E) be the complete 3-uniform hypergraph, where the vertex set is V={x1,x2,⋯,xv}, in which the edge set E is of all triples. Let ST denote the special tetrahedron with four edges, where each edge contains three vertices of degree 2. In this paper, we consider the decomposition and packing of a complete 3-uniform hypergraph of an λ-fold special tetrahedron. Firstly, the necessary conditions for the existence of the λ-fold ST-decomposition are discussed in four distinct cases. Secondly, according to the recursive constructions, the required designs of small orders are found. For hypergraphs with large orders, they can be recursively generated using some designs of small orders. Then, it is proven that the above necessary conditions are sufficient. Finally, we prove that a maximum ST-packing of a complete 3-uniform hypergraph Kv(3) exists for all v≥6 and λ≥1.
A Dynamic Tasking-Based Evolutionary Algorithm for Bi-Objective Feature Selection
Authors: Xu Hang
Published: May 2024

Feature selection in classification is a complex optimization problem that cannot be solved in polynomial time. Bi-objective feature selection, aiming to minimize both selected features and classification errors, is challenging due to the conflict between objectives, while one of the most effective ways to tackle this is to use multi-objective evolutionary algorithms. However, very few of these have ever reflected an evolutionary multi-tasking framework, despite the implicit parallelism offered by the population-based search characteristic. In this paper, a dynamic multi-tasking-based multi-objective evolutionary algorithm (termed DTEA) is proposed for handling bi-objective feature selection in classification, which is not only suitable for datasets with relatively lower dimensionality of features, but is also suitable for datasets with relatively higher dimensionality of features. The role and influence of multi-tasking on multi-objective evolutionary feature selection were studied, and a dynamic tasking mechanism is proposed to self-adaptively assign multiple evolutionary search tasks by intermittently analyzing the population behaviors. The efficacy of DTEA is tested on 20 classification datasets and compared with seven state-of-the-art evolutionary algorithms. A component contribution analysis was also conducted by comparing DTEA with its three variants. The empirical results show that the dynamic-tasking mechanism works efficiently and enables DTEA to outperform other algorithms on most datasets in terms of both optimization and classification.
Manufacturer vs. Retailer: A Comparative Analysis of Different Government Subsidy Strategies in a Dual-Channel Supply Chain Considering Green Quality and Channel Preferences
Authors: Xu Yan , Tian Yan , Pang Chuan , Tang Huajun
Published: May 2024

As escalating environmental pollution results from economic development, the green supply chain is vital in enhancing ecological quality. In light of the rapid growth of online shopping, the dual-channel supply chain has gained significant popularity. Governments have implemented policies to achieve carbon peaks and neutrality worldwide. Considering green quality and channel preferences, this study constructs a Stackelberg model led by the manufacturer within a dual-channel supply chain to compare the effects under two government subsidy strategies. A Stackelberg game-theoretic approach is applied to analyze the model. The findings indicate the following: (1) Increases in the subsidy coefficient can increase product greenness and the overall profit in both subsidy strategies, which makes sense; (2) When direct sales channels become dominant, subsidizing the manufacturer proves superior to subsidizing the retailer in terms of promoting green quality and overall profit, which extends existing studies of government subsidy decisions. Furthermore, subsidizing the retailer may negatively affect the total supply chain profit; (3) Consistent with previous literature, intense competition between manufacturers and retailers is expected to enhance the overall profit of the supply chain; (4) Interestingly, customer preference for online channels does not influence product green quality under manufacturer subsidization strategies but exhibits a negative impact under retailer subsidization strategies. Finally, this research provides managerial implications for decision-makers and potential issues for future research.
Analysis of Nonlinear Vibration Characteristics and Whirl Behavior of Dual-Rotor Systems with Inter-Shaft Rub Impact
Authors: Wang Zhi , Sun Rui , Liu Yu , Yao Yudong , Tian Jing
Published: May 2024

Previous studies on rub-impact faults have mainly focused on the rub-impact between rotors and stators, with less research on inter-rotor rub impact. The impact of inter-rotor rub impact on rotor nonlinear vibration is particularly significant. This study investigates the effects of inter-shaft rub impact on the vibration characteristics and whirl behavior of dual-rotor systems. Initially, a dual-rotor model with inter-shaft bearings is established using the finite element method, and inter-shaft rub-impact forces are derived based on contact mechanics. Next, the system response is solved using the Newmark method. Vibration characteristics are analyzed through Campbell diagrams, 3D waterfall plots, time-frequency domain plots, and steady-state rub-impact force plots. Finally, the influence of inter-shaft rub impact on the whirl behavior of the dual-rotor system is studied based on the theory of full-spectrum analysis. The study concludes that inter-shaft rub-impact faults shift the system’s resonance points backward, increase harmonic and combination frequency components, and significantly affect the system response under dual-rotor co-rotation. Excessive friction can lead to self-excited vibrations and sudden amplitude increases, particularly in the LP rotor frequency. Additionally, inter-shaft rub impact primarily affects the whirl behavior of the LP-compressor disk1, showing multiple cycles of forward and backward whirl alternation during acceleration due to combined unbalanced and rub-impact excitations.
Menopausal Hormone Therapy, an Ever-Present Topic: A Pilot Survey about Women’s Experience and Medical Doctors’ Approach
Authors: Aquino Carmen Imma , Stampini Viviana , Osella Elena , Troìa Libera , Rocca Clarissa , Guida Maurizio , Faggiano Fabrizio , Remorgida Valentino , Surico Daniela
Published: May 2024

Background and Objective: Menopause can be associated with many clinical manifestations: vasomotor symptoms, urogenital problems, and additional psychological disturbances, such as anxiety, mood changes, and sleep alterations. The prolonged lack of hormones also increases the risk of long-term consequences. Hormone Replacement Treatment (HRT) in menopause consists of the administration of estrogen, alone or associated to progesterone, to relieve these uncomfortable disturbances and to prevent the onset of other pathologic conditions. The aim of this study is to examine the prevalence of HRT use in a sample of menopausal women and their experience with menopause and HRT. This study also investigates the knowledge of general practitioners (GPs) and gynecologists about HRT and its prescription. Materials and Methods: We conducted a cross-sectional population survey on 126 women of 50–59 years in an industrial city in the North of Italy, Vercelli (Novara), in Eastern Piedmont. We also presented a questionnaire on the topic to 54 medical doctors (GPs and gynecologists) of the same area. Results: The prevalence of HRT use in our sample was 11.9%. In total, a good percentage of the users affirmed to be satisfied with HRT. Additionally, a minority of women reported being ideally against the use of replacement hormones, were advised against using HRT by doctors, and did not use it because of the fear of side effects. We found a positive association between patient education, health care attitude, and HRT usage. A significant number of women knew about HRT from the media, and most of them were not informed by a health professional. Despite this, the interviewed doctors considered their knowledge about HRT as ‘good’ and would recommend HRT: only 5.6% would not prescribe it. Conclusions: Our results highlight the need for information about HRT among patients and health professionals, along with the need for more effective communication, evaluation, and suggestion of treatment.
Prediction of Diabetes and Prediabetes among the Saudi Population Using a Non-Invasive Tool (AUSDRISK)
Authors: Alshaikh Ayoub Ali , Al-Qahtani Faisal Saeed , Taresh Hassan Misfer N , Hayaza Rand Abdullah A , Alqhtani Sultan Saeed M , Summan Sarah Ibrahim , Al Mansour Sultan Abdullah , Alsultan Omar Hezam A , Asiri Hassan Yahya M , Alqahtani Yazeed Mohammed S , Alzailaie Waleed Khaled A , Alamoud Ahmed Abdullah A , Ghazy Ramy Mohamed
Published: May 2024

Background and Objectives: Screening for type 2 diabetes mellitus (DM2) aims to identify asymptomatic individuals who may be at a higher risk, allowing proactive interventions. The objective of this study was to predict the incidence of DM2 and prediabetes in the Saudi population over the next five years. Materials and Methods: The study was conducted in the Aseer region through August 2023 using a cross-sectional survey for data collection. A multistage stratified random sampling technique was adopted, and data were collected through face-to-face interviews using the validated Arabic version of the Australian Type 2 Diabetes Risk Assessment Tool (AUSDRISK). Results: In total, 652 individuals were included in the study. Their mean age was 32.0 ± 12.0 years; 53.8% were male, 89.6% were from urban areas, and 55.8% were single. There were statistically significant differences between males and females in AUSDRISK items, including age, history of high blood glucose, use of medications for high blood pressure, smoking, physical activity, and measurements of waist circumference (p < 0.05). Based on AUSDRISK scores, 46.2% of the included participants were predicted to develop impaired glucose tolerance within the coming five years (65.8% among females vs. 23.6%), and 21.9% were predicted to develop DM2 (35.6% among males vs. 6.0% among females); this difference was statistically significant (p = 0.0001). Conclusions: Urgent public health action is required to prevent the increasing epidemic of DM2 in Saudi Arabia.
Progress in Research on White Organic Light-Emitting Diodes Based on Ultrathin Emitting Layers
Authors: Zhao Wencheng , Hu Xiaolin , Kong Fankang , Tang Jihua , Yan Duxv , Wang Jintao , Liu Yuru , Sun Yuanping , Sheng Ren , Chen Ping
Published: May 2024

White organic light-emitting diodes (WOLEDs) hold vast prospects in the fields of next-generation displays and solid-state lighting. Ultrathin emitting layers (UEMLs) have become a research hotspot because of their unique advantage. On the basis of simplifying the device structure and preparation process, they can achieve electroluminescent performance comparable to that of doped devices. In this review, we first discuss the working principles and advantages of WOLEDs based on UEML architecture, which can achieve low cost and more flexibility by simplifying the device structure and preparation process. Subsequently, the successful applications of doping and non-doping technologies in fluorescent, phosphorescent, and hybrid WOLEDs combined with UEMLs are discussed, and the operation mechanisms of these WOLEDs are emphasized briefly. We firmly believe that this article will bring new hope for the development of UEML-based WOLEDs in the future.
Trypanosoma cruzi in Bats (Chiroptera; Mammalia) from the Brazilian Atlantic Forest, São Paulo State
Authors: França Danilo Alves de , Louro Mariana , Zúquete Sara , Zanini Dayane da Silva , Moraes Gustavo Nunes de , Rocha Gabrielle dos Santos , Biondo Leandro Meneguelli , Fornazari Felipe , Menozzi Benedito Donizete , Fonseca Isabel Pereira da , Langoni Helio
Published: May 2024

The causative agent of Chagas disease is Trypanosoma cruzi, which is widely distributed throughout the South American continent and extends into North America. Its occurrence in bats is poorly described and may impact the disease’s maintenance and epidemiology. The aim of this study was to detect the agent by PCR assays targeting kDNA and nuclear DNA in the organs of 203 urban bats and rural vampire bats from the Brazilian Atlantic Forest, São Paulo state, during the pandemic period from 2020 to 2022. In total, 6 of the 203 bats (2.97%) were positive for T. cruzi. Infection was detected in 2% (2/101) of Desmodus rotundus, 33% (1/3) of Nyctinomops laticaudatus, 25% (1/4) of Artibeus lituratus, 4% (1/24) of Eumops glaucinus and in 2% (1/41) of Molossus molossus. The gene sequences obtained were assessed for quality and deposited in a public repository. Fruit bats were statistically associated with positivity for T. cruzi. To our knowledge, this study detected T. cruzi for the first time in bats from São Paulo state and in N. laticaudatus and E. glaucinus species.
Heterogeneous Organocatalysts for Light-Driven Reactions in Continuous Flow
Authors: Di Carmine Graziano , D’Agostino Carmine , Bortolini Olga , Poletti Lorenzo , De Risi Carmela , Ragno Daniele , Massi Alessandro
Published: May 2024

Within the realm of organic synthesis, photocatalysis has blossomed since the beginning of the last decade. A plethora of classical reactivities, such as selective oxidation of alcohol and amines, redox radical formation of reactive species in situ, and indirect activation of an organic substrate for cycloaddition by EnT, have been revised in a milder and more sustainable fashion via photocatalysis. However, even though the spark of creativity leads scientists to explore new reactions and reactivities, the urgency of replacing the toxic and critical metals that are involved as catalysts has encouraged chemists to find alternatives in the branch of science called organocatalysis. Unfortunately, replacing metal catalysts with organic analogues can be too expensive sometimes; however, this drawback can be solved by the reutilization of the catalyst if it is heterogeneous. The aim of this review is to present the recent works in the field of heterogeneous photocatalysis, applied to organic synthesis, enabled by continuous flow. In detail, among the heterogeneous catalysts, g-CN, polymeric photoactive materials, and supported molecular catalysts have been discussed within their specific sections, rather than focusing on the types of reactions.
Recent Advances in the Synthesis of Rosettacin
Authors: Tang Xiao , Jiang Yukang , Song Liangliang , Van der Eycken Erik V.
Published: May 2024

Camptothecin and its analogues show important antitumor activity and have been used in clinical studies. However, hydrolysis of lactone in the E ring seriously attenuates the antitumor activity. To change this situation, aromathecin alkaloids are investigated in order to replace camptothecins. Potential antitumor activity has obtained more and more attention from organic and pharmaceutical chemists. As a member of the aromathecin alkaloids, rosettacin has been synthesized via different methods. This review summarizes recent advances in the synthesis of rosettacin.
A Study on the Ability of Nanomaterials to Adsorb NO and SO2 from Combustion Gases and the Effectiveness of Their Separation
Authors: Constantinescu Marius , Bucura Felicia , Roman Antoaneta , Botoran Oana Romina , Ionete Roxana-Elena , Spiridon Stefan Ionut , Ionete Eusebiu Ilarian , Zaharioiu Anca Maria , Marin Florian , Badea Silviu-Laurentiu , Niculescu Violeta-Carolina
Published: May 2024

Climate neutrality for the year 2050 is the goal assumed at the level of the EU27+UK. As Romania is no exception, it has assumed the gradual mitigation of pollution generated by the energy sector, and by 2030, according to ‘Fit for 55’, the share of energy from renewable sources must reach 42.5% from total energy consumption. For the rest of the energy produced from traditional sources, natural gas and/or coal, modern technologies will be used to retain the gaseous noxes. Even if they are not greenhouse gases, NO and SO2, generated from fossil fuel combustion, cause negative effects on the environment and biodiversity. The adsorption capacity of different materials, three nanomaterials developed in-house and three commercial adsorbents, both for NO and SO2, was tackled through gas chromatography, elemental analysis, and Fourier-transform infrared spectroscopy. Fe-BTC has proven to be an excellent material for separation efficiency and adsorption capacity under studied conditions, and is shown to be versatile both in the case of NO (80.00 cm3/g) and SO2 (63.07 cm3/g). All the developed nanomaterials generated superior results in comparison to the commercial adsorbents. The increase in pressure enhanced the performance of the absorption process, while temperature showed an opposite influence, by blocking the active centers on the surface.
Tunable Unexplored Luminescence in Waveguides Based on D-A-D Benzoselenadiazoles Nanofibers
Authors: Tardío Carlos , Pinilla-Peñalver Esther , Donoso Beatriz , Torres-Moya Iván
Published: May 2024

A set of novel Donor-Acceptor-Donor (D-A-D) benzoselenadiazole derivatives has been synthesized and crystallized in nanocrystals in order to explore the correlation between their chemical structure and the waveguided luminescent properties. The findings reveal that all crystals exhibit luminescence and active optical waveguiding, demonstrating the ability to adjust their luminescence within a broad spectral range of 550–700 nm depending on the donor group attached to the benzoselenadiazole core. Notably, a clear relationship exists between the HOMO-LUMO energy gaps of each compound and the color emission of the corresponding optical waveguides. These outcomes affirm the feasibility of modifying the color emission of organic waveguides through suitable chemical functionalization. Importantly, this study marks the first utilization of benzoseleniadiazole derivatives for such purposes, underscoring the originality of this research. In addition, the obtention of nanocrystals is a key tool for the implementation of miniaturized photonic devices.
Cytotoxic Effect of Amyloid-β1-42 Oligomers on Endoplasmic Reticulum and Golgi Apparatus Arrangement in SH-SY5Y Neuroblastoma Cells
Authors: Jarero-Basulto José J. , Gasca-Martínez Yadira , Rivera-Cervantes Martha C. , Gasca-Martínez Deisy , Carrillo-González Nidia Jannette , Beas-Zárate Carlos , Gudiño-Cabrera Graciela
Published: May 2024

Amyloid-β oligomers are a cytotoxic structure that is key for the establishment of the beginning stages of Alzheimer’s disease (AD). These structures promote subcellular alterations that cause synaptic dysfunction, loss of cell communication, and even cell death, generating cognitive deficits. The aim of this study was to investigate the cytotoxic effects of amyloid-β1-42 oligomers (AβOs) on the membranous organelles involved in protein processing: the endoplasmic reticulum (ER) and Golgi apparatus (GA). The results obtained with 10 μM AβOs in SH-SY5Y neuroblastoma cells showed that oligomeric structures are more toxic than monomers because they cause cell viability to decrease as exposure time increases. Survivor cells were analyzed to further understand the toxic effects of AβOs on intracellular organelles. Survivor cells showed morphological alterations associated with abnormal cytoskeleton modification 72–96 h after exposure to AβOs. Moreover, the ER and GA presented rearrangement throughout the cytoplasmic space, which could be attributed to a lack of constitutive protein processing or to previous abnormal cytoskeleton modification. Interestingly, the disorganization of both ER and GA organelles exposed to AβOs is likely an early pathological alteration that could be related to aberrant protein processing and accumulation in AD.
Placebo Effect of Caffeine on Physiological Parameters and Physical Performance
Authors: Ortiz-Sánchez David , Bravo-Sánchez Alfredo , Ramírez-delaCruz María , Abián Pablo , Abián-Vicén Javier
Published: May 2024

This study aimed to analyse the placebo effect associated with a high dose of caffeine (9 mg/kg) on heart rate and its variability and on strength tests. Methods: 18 participants experienced in strength training (19.7 ± 2.3 years; 72.2 ± 15.0 kg; 169.6 ± 9.0 cm) performed two days of trials (caffeine-informed/placebo-ingested (placebo) and non-ingested (control)). Firstly, heart rate and its variability were measured while participants lay down for 15 min. After that, bench press and squat tests were performed at 3 different loads (50%, 75% and 90% of 1RM). Perception of performance, effort and side effects were also evaluated. Results: no differences were found in the vast majority of strength variables analysed. Resting heart rate decreased in the placebo trial (60.39 ± 10.18 bpm control vs. 57.56 ± 9.50 bpm placebo, p = 0.040), and mean RR increased (1020.1 ± 172.9 ms control vs. 1071.5 ± 185.7 ms placebo, p = 0.032). Heart rate variability and perception of performance and effort were similar between conditions (p > 0.05 in all cases). Side effects such as activeness and nervousness were reported while consuming the placebo. Conclusions: the placebo effect did not modify performance in the majority of the strength test variables, HRV and perception of performance and effort. However, resting heart rate was reduced, mean RR increased, and some side effects appeared in the placebo trial.