bluuebunny/crossref_metadata_2025 huggingface dataset:
Role Of Gastric pH In Post Pancreatectomy Hemorrhage After Pancreaticogastrostomy In Whipple Procedure
Authors: Riyaz Mohammad , Devakumar Satish , Kamal Harshit , Jeswanth Satyanesan
Published: April 2023

BACKGROUND: Postpancreatectomy hemorrhage (PPH) is one of the most severe complications after pancreaticoduodenectomy.
METHODS:This prospective study was done in a tertiary care center to find out the role of gastric pH in postpancreatectomy hemorrhage. The gastric pH study is done by Ryle’s tube aspiration – 1) fasting ph value 1 hour before surgery and second value after 48 hrs of surgery.
RESULTS: Of the total 27 patients who underwent Whipple’s procedure, 6 patients develop postpancreatectomy hemorrhage. On applying unpaired T test it was found that the difference was significant (p value <0.05) in the mean pH values among those with PPH when compared to those without PPH. The mean pH levels (mean ± Sd) among bleeders was 3.39 ± 1.80 and among non bleeder was 6.33 ± 1.03. The mean pH values were significantly lower in those where bleeding was present. The area under the curve of the ROC analysed and it was found that that the PH of 4.1 had maximum sensitivity (50%) and specificity (95.2%). Based on this, association between bleeding and PH value of 4.1 as cutoff was analysed using chi square test and it was found that the incidence of bleeding was significantly (p value <0.05) higher among those who had a PH value <4.1 (75%) compared to those with PH >4.1 (13%)

CONCLUSION:

Persistent low gastric pH is associated with increased risk of post pancreatectomy
Hemorrhage.Suppression of the intrinsic gastric acid secretion will be helpful in reducing the risk of bleeding after Pancreaticogastrostomy in Whipple procedure.
Effects of memory dependent heat transfer on the Rayleigh wave propagation in non-local micropolar thermoelastic medium
Authors: Ahmed Lukman , Sawhney Shruti , Singh Kulwinder
Published: April 2023

This paper presents the problem of Rayleigh wave propagation in a non-local micropolar thermoelastic material within the framework of memory-dependent heat conduction and Eringen's non-local theory of elasticity. The memory-dependent derivative in the heat conduction equation makes it possible to describe the memory effects on the current temperature field from the previous temperature state with a time delay parameter and is characterized by different kernel functions over the slipping interval. The secular equation of Rayleigh waves, describing the dependence of Rayleigh wave speed on the time delay parameter and non-local parameter, is obtained analytically under stress-free and thermally insulated/isothermal boundary conditions. In a particular case, the secular equation obtained is in agreement with previously published results. To analyze the effects of key factors such as the non-local parameter, delay parameter, and kernel functions on Rayleigh wave speed, numerical computations have been performed by considering the relevant parameters of an aluminum-epoxy composite material and depicted graphically. The graphical analysis shows that there are significant effects of non-locality in the material and memory-dependent heat transfer on the Rayleigh wave speed.
Ceftiofur Treatment of Sows Results in Long-Term Alterations in the Nasal Microbiota of the Offspring That Can Be Ameliorated by Inoculation of Nasal Colonizers
Authors: Blanco-Fuertes Miguel , Sibila Marina , Franzo Giovanni , Obregon-Gutierrez Pau , Illas Francesc , Correa-Fiz Florencia , Aragon Virginia
Published: April 2023

Background
The nasal microbiota of the piglet is a reservoir for opportunistic pathogens that can cause polyserositis, such as Glaesserella parasuis, Mycoplasma hyorhinis or Streptococcus suis. Antibiotic treatment is a strategy to control these diseases, but it has a detrimental effect on the microbiota. We followed the piglets of 60 sows from birth to 8 weeks of age, to study the effect of ceftiofur on the nasal colonization by these pathogens and the nasal microbiota when the treatment was administered to sows or their litters. We also aimed to revert the effect of the antibiotic on the nasal microbiota by the inoculation at birth of nasal colonizers selected from healthy piglets. Nasal swabs were collected at birth, and at 7, 15, 21 and 49 days of age, and were used for pathogen detection by PCR and bacterial culture, 16S rRNA amplicon sequencing and whole shotgun metagenomics. Weights, clinical signs and production parameters were also recorded during the study.
Results
The composition of the nasal microbiota of piglets changed over time, with a clear increment of Clostridiales at the end of nursery. The administration of ceftiofur induced an unexpected temporary increase in alpha diversity at day 7 mainly due to colonization by environmental taxa. Ceftiofur had a longer impact on the nasal microbiota of piglets when administered to their sows before farrowing than directly to them. This effect was partially reverted by the inoculation of nasal colonizers to newborn piglets and was accompanied by a reduction in the number of animals showing clinical signs (mainly lameness). Both interventions altered the colonization pattern of different strains of the above pathogens. In addition, the prevalence of resistance genes increased over time in all the groups but was significantly higher at weaning when the antibiotic was administered to the sows. Also, ceftiofur treatment induced the selection of more beta-lactams resistance genes when it was administered directly to the piglets.
Conclusions
This study shed light on the effect of the ceftiofur treatment on the piglet’s nasal microbiota over time and demonstrated for the first time the possibility of modifying the piglets’ nasal microbiota by inoculating natural colonizers of the upper respiratory tract.
Is the nuclear attraction just magnetic moment interaction between nucleons?
Authors: Zexin Cao , Ling Liu
Published: April 2023

By reexamining the magnetic moment interaction between nucleons, it is argued in this article that the formula for calculating magnetic induction generated by magnetic moments derived from electrodynamics under far-field conditions is unsuitable for calculating near-field interactions between magnetic moments. When nucleons undergo magnetic moment interactions under near-field conditions, there is a strong magnetic flux coupling, similar to that in a transformer circuit.By assuming magnetic flux quantization generated by nucleons, the magnetic induction intensity can reach 105 T, providing enough magnetic attraction to overcome the Coulomb repulsion. A reasonable explanation for the binding energy of atomic nuclei under magnetic moment interaction conditions was provided. It is suggested that the upper limit of binding energy resulting from the magnetic moment interaction between protons and neutrons is approximately 125 MeV. The article analyzes the possibility of the existence of 2He nuclei composed of only protons and explores the relationship between neutron decay and strong magnetic fields. In the analysis of the magnetic structure of 4H nucleus, it is pointed out that the magnetic moment interaction is likely the fundamental reason for nuclear force saturation and multi-body force.A reasonable explanation for nuclear force can be provided through the hypothesis of nucleon magnetic flux quantization and the modification of the magnetic moment-field formula derived under far-field conditions. It suggests that nuclear force and strong interaction are likely to be electromagnetic forces. Furthermore, atomic nuclei may only be made up of buckyballs with equal amounts of positive charge and no net charge.
Widespread annual occurrence of pesticides within designated Critical Habitats for Endangered prairie butterflies
Authors: Runquist Erik , Nordmeyer Cale , Stapleton Seth
Published: April 2023

Insect declines have become pronounced in prairie ecosystems, particularly in areas of agricultural intensification. Non-target pesticide exposure has been raised as a key concern for prairie remnant health. We do not understand the extent of that exposure risk, particularly across seasons and multi-year timeframes. Over nine years, we analyzed grass and soil samples for the presence of hundreds of pesticides from five prairies in Minnesota and South Dakota that are designated as Critical Habitat for two endangered butterflies: Poweshiek skipperling and Dakota skipper. We found dozens of pesticides across all sites and years on their larval host grasses. Interiors of prairies were not less likely to have detectable pesticides than prairie-agriculture edges. Broad-spectrum organophosphate and pyrethroid insecticides were common in late season. Chlorpyrifos quantities were higher at sites where both endangered species have been extirpated. Few pesticides were detected in soil or early season grass samples. The risk associated with the prevalence and quantities of pesticides we observed likely underestimates the overall risk. Implications for Conservation: Our work demonstrates protected prairies are not immune to the risk of pesticide exposure, and that this may impact planned efforts to re-establish lost populations of imperiled prairie insect species, including endangered butterflies.
WITHDRAWN: Long-term, Single-Center Study Comparing Open and Laparoscopic Procedures for Congenital Midureteral Obstruction in Children
Authors: Zhou Guanglun , Jiang Man , Yin Jianchun , Liu Xiaodong , Sun Junjie , Li Shoulin
Published: April 2023

Purpose To compare the safety and outcomes of open and laparoscopic procedures in the management of congenital midureteral obstruction in children (CMO).Methods Between February 2008 and February 2022, a total of 18 patients underwent open ureteroureterostomy (OU group), and 26 underwent laparoscopic ureteroureterostomy (LU group). The operative time, postoperative hospital stay, hospital costs, postoperative complications, and success rates of the two groups were compared.Results The median age of the patients was 59 months, with 29 patients presenting with asymptomatic hydronephrosis, 12 with intermittent abdominal pain, and 3 with flank mass. The median follow-up time was 42 months, and all patients were successfully treated surgically. The operative time and postoperative hospital stay in the LU group were shorter than those in the OU group (106.3 ± 21.4 vs. 85.8 ± 16.5 min, 11.6 ± 1.9 vs. 8.3 ± 1.7 days, respectively; p < 0.05). The OU group had 2 postoperative complications: 1 case of wound infection and 1 case of febrile urinary tract infection. One case of postoperative urinary tract infection occurred in the LU group.Conclusions Our data showed that laparoscopic ureteroureterostomy is a safe and effective treatment for congenital midureteral obstruction in children, and provides several advantages, including fewer postoperative complications, shorter postoperative hospital stay, and a shorter operative time. Laparoscopic procedures should be the first choice for treating children with congenital midureteral obstructions.
Electrophysiological activity from the eye muscles, cerebellum and cerebrum during reflexive and voluntarily timed blinks
Authors: Todd Neil , Govender Sendhil , Keller Peter , Colebatch James
Published: April 2023

We report an experiment to investigate the role of the cerebellum and cerebrum in motor learning of timed movements. Eleven healthy human subjects were recruited to perform two experiments, the first a classical eye-blink conditioning procedure with an auditory tone as conditional stimulus (CS) and vestibular unconditional stimulus (US) in the form of a double head-tap. In the second experiment subjects were asked to blink voluntarily in synchrony with the double head-tap US preceded by a CS. Electrophysiological recordings were made of extra-ocular EMG and EOG at infra-ocular sites (IO1/2), EEG from over the frontal eye-fields (C3’/C4’) and from over the posterior fossa over the cerebellum for the electro-cerebellogram (ECeG). The behavioural outcomes of the experiments showed weak reflexive conditioning for the first experiment despite the double tap but robust well-synchronised voluntary blinks for the second. Voluntary blinks were larger than the reflex ones. For the voluntary task a contingent negative variation (CNV) was also present in the EEG leads prior to movement, and modulation of the high-frequency EEG occurred during movement. Stimulus-related cerebellar activity was prominent in the high-frequency ECeG for both conditions, while movement-related cerebellar activity was additionally present in the voluntary condition. These results demonstrate a role for the cerebellum in voluntary timed movement analogous to that in classical conditioning.
Magnetic resonance imaging of the dromedary camel carpus
Authors: Nahas Ayman El , Hagag Usama
Published: April 2023

Background: The dromedary camel (camelus dromedarius) carpal joint presents multiple joints and constitutes several bones and soft tissues. Radiography and/or ultrasonography of the carpus are challenging due to structural superimposition. High-field magnetic resonance imaging (MRI) technique precludes superimposed tissues and offers high soft tissue contrast in multiple sequences and planes. Hence, understanding the normal MRI anatomy is crucial during clinical investigations. Magnetic resonance imaging is highly sensitive for investigation of soft tissues and articular cartilage; therefore, it is extensively used for outlining joint anatomy and evaluation of a wide range of musculoskeletal conditions. MRI images of a specific anatomical region acquired by using multiple sequences in various planes are necessary for a complete MRI examination. Given the dearth of information on the MRI features of the dromedary camel carpus, the current study demonstrates the MRI appearance of the clinically significant structures in the camel carpus in various sequences and planes using a high-field 1.5 Tesla superconducting magnet. For this purpose, twelve cadaveric forelimbs, obtained from 6 clinically sound lameness free adult dromedary camels, were examined.
Results: The cortex and medulla of the radius, carpal bones and metacarpus were evaluated. Articular cartilage of the carpal joints was depicted and showed intermediate intensity. Carpal tendons expressed lower signal intensity in all pulse sequences. The collateral and inter-carpal ligaments showed mixed signal intensity.
Conclusions: The obtained data outlines the validation of MRI for investigation of the camel carpus and could set as a reference for interpretation in clinical patients.
Genomic, transcriptomic and epigenomic sequencing data of the B- cell leukemia cell line REH
Authors: Wiklander Mariya Lysenkova , Övernäs Elin , Lagensjö Johanna , Raine Amanda , Petri Anna , Wiman Ann-Christine , Ramsell Jon , Marincevic-Zuniga Yanara , Gezelius Henrik , Martin Tom , Bunikis Ignas , Ekberg Sara , Erlandsson Rikard , Larsson Pontus , Mosbech Mai-Britt , Häggkvist Susana , Kerje Susanne Hellstedt , Feuk Lars , Ameur Adam , Liljedahl Ulrika , Nordlund Jessica
Published: April 2023

Objectives

The aim of this data paper is to describe a collection of 33 genomic, transcriptomic and epigenomic sequencing datasets of the B-cell acute lymphoblastic leukemia (ALL) cell line REH. REH is one of the most frequently used cell lines for functional studies of pediatric ALL, and these data provide a multi-faceted characterization of its molecular features. The datasets described herein, generated with short- and long-read sequencing technologies, can both provide insights into the complex aberrant karyotype of REH, and be used as reference datasets for sequencing data quality assessment or for methods development.

Data Description

This paper describes 33 datasets corresponding to 450 GB of raw sequencing data generated from the REH cell line. These datasets include five different approaches for whole genome sequencing (WGS) on four sequencing platforms, two RNA sequencing (RNA-seq) techniques on two different sequencing platforms, DNA methylation sequencing, and single-cell ATAC-sequencing.
Kazdan-Warner problem on compact Riemann surfaces with smooth boundary
Authors: Venizelos Alexander
Published: April 2023

The authors have requested that this preprint be removed from Research Square.
Fetal origins of obesity: a novel pathway of regulating appetite neurons in the hypothalamus of growth restricted rat offspring
Authors: Han Weiling , Song Zhaoyi , Shan Dan , Shi Qingyun
Published: April 2023

Purpose Fetal growth restriction causes a series of sequelae, some of which, such as hyperphagia, reduced satiety and postnatal obesity, are believed in associated with embryonic hypothalamic neurons impairment. The mechanisms underlying the linkage of fetal brain injuries to break the energy homeostasis have not been elucidated completely. Here, we aim to investigate the effect of intrauterine energy-restriction on remodeling appetite neurons in the hypothalamus of fetal and postnatal infant rats.Methods Low-protein (8%) diet combined with 75% energy restriction was used to establish an animal model. Rats offspring brain tissues, harvested from embryo day 18th and postnatal infant day 1st, were sampled for dependent regulator analyses and master neuron assessment.Results Growth restricted rats showed the increased expression of Bsx and NPY in the hypothalamus as well as remodeling hypothalamic neurons differentiation compared to controls. Intriguingly, in cells cultured in vitro test, we found that activated effects of Bsx and NPY could be exacerbated by DNMT1 inhibitor.Conclusions In embryonic and early postnatal stage of FGR rats, we detected high concentrations of orexigenic neurons in the hypothalamus. DNMT1 activity is correlated with early embryonic neurogenesis by mediating the expression of Bsx and NPY. It may be one of the reasons for the abnormal development of the appetite regulation pathway and higher susceptibility to obesity in FGR offspring.
The Determinants of CO2 Emissions in the Context of ESG Models at World Level
Authors: Costantiello Alberto , Leogrande Angelo
Published: April 2023

We estimate the determinants of CO2 Emissions-COE in the context of Environmental, Social and Governance-ESG model at world level. We use data of the World Bank for 193 countries in the period 2011-2020. We found that the level of COE is positively associated, among others to “Methane Emissions”, “Research and Development Expenditures”, and negatively associated among others to “Renewable Energy Consumption” and “Mean Drought Index”. Furthermore, we have applied a cluster analysis with the k-Means algorithm optimized with the Elbow Method and we find the presence of four cluster. Finally, we apply eight machine-learning algorithms for the prediction of the future value of COE and we find that the Artificial Neural Network-ANN algorithm is the best predictor. The ANN predicts a reduction in the level of COE equal to 5.69% on average for the analysed countries.
JEL Classification: D7, D70, D72, D73, D78
Effect of 2-methoxyestradiol treatment on early- and late-stage breast cancer progression in a mouse model
Authors: Peta Kimberly T. , Durandt Chrisna , Heerden Marlene B. , Joubert Anna M. , Pepper Michael S. , Ambele Melvin A.
Published: April 2023

BACKGROUND: The prevalence of breast cancer (BC) continues to increase and is the leading cause of cancer deaths in many countries. Numerous in vitro and in vivo studies have demonstrated that 2-methoxyestradiol (2-ME) has antiproliferative and antiangiogenic effects in BC thereby inhibiting tumour growth and metastasis. We compared the effect of 2-ME in early and late-stage BC using a transgenic mouse model – FVB/N-Tg(MMTV-PyVT) – of spontaneously development of aggressive mammary carcinoma with lung metastasis.
METHODS: Mice received 100 mg/kg 2-ME treatment immediately when palpable mammary tumours were identified (early-stage BC; experimental group 1) and 28 days after palpable mammary tumours were detected (late-stage BC; experimental group 2). 2-ME was administered via oral gavage three times a week for 28 days after initiation of treatment, while control mice received the vehicle containing 10% dimethyl sulfoxide (DMSO) and 90% sunflower oil for the same duration as the treatment group. Mammary tumours were measured weekly over the 28-day period and at termination, blood, mammary and lung tissue were collected for analysis. Mice with a tumour volume threshold of 4000mm3 were euthanized before the treatment regime was completed.
RESULTS: 2-ME treatment of early-stage BC led to lower levels of mammary tumour necrosis, while tumour mass and volume were increased. Additionally, necrotic lesions and anti-inflammatory CD163 expressing cells were more frequent in pulmonary metastatic tumours in this group. In contrast, 2-ME treatment of late-stage BC inhibited tumour growth over the 28-day period, and resulted in increased CD3+ cell number and tumour necrosis. Furthermore, 2-ME treatment slowed down pulmonary metastasis, but did not increase survival of late-stage BC mice. Besides late-stage tumour necrosis, none of the other results were statistically significant.
CONCLUSION: This study demonstrates that 2-ME treatment has an antitumour effect on late-stage BC, however with no increase in survival rate, while the treatment failed to demonstrate any benefit in early-stage BC.
Understanding the impact of along-transect resolution on acoustic surveys
Authors: Boyra Guillermo , Paradinas Iosu , Rico Iñaki , Martínez Udane , Nogueira Enrique
Published: April 2023

The distance between successive echosounder transmissions or “pings” is the main parameter determining the resolution of sampling along a transect in acoustic surveys. An increase in either ping interval or vessel speed increases the inter-ping distance, hence decreasing the effective resolution. In this study, we analysed whether a loss in along-transect resolution affects the mean acoustic backscattering energy, leading to uncertainty and/or bias in abundance estimates. To this end, we echo-integrated a real acoustic survey, followed by the application of a systematic resampling scheme to simulate a decrease in pinging resolution. For each transect, the mean NASC calculated at each resolution was compared with the mean NASC at the original resolution. Transects were characterised according to their heterogeneity and spatial autocorrelation to investigate their effect on the relationship between abundance error and sampling resolution. Uncertainty was seen to increase with decreasing resolution, with higher heterogeneity and lower spatial autocorrelation accelerating the rise in imprecision. Although the mean bias across replicates was zero, the asymmetry of the bias distributions increased with decreasing resolution, leading to an increasing probability and magnitude of underestimation (https://aztigps.shinyapps.io/PingRateStudio/).
Association of stress management behavior and diabetic self-care Practice among Diabetes Type II Patients in North Shoa Zone: A Cross-Sectional Study
Authors: Eshete Akine , Mohammed Sadat , Deress Tilahun , Kifleyohans Tewodros , Assefa Yibeltal
Published: April 2023

Background The cornerstone of managing diabetes is diabetic self-care behaviors, however many people with diabetes do not engage in enough of these actions. Effective stress management behaviors have a positive effect on diabetes self-care. The purpose of this study was to investigate the association between diabetic self-care behaviors and stress-coping behaviors in patients with type II diabetes.Method A facility-based cross-sectional study was undertaken in the North Shoa zone from February 24 to March 25, 2022. The study involved 432 types II diabetic patients who were chosen at random from eight public hospitals. Data were entered into Epi Data V.3.1 and analyzed using SPSS version 22. Data for continuous variables were reported as means of standard deviations and percentages for categorical variables. Descriptive statistic was used to summarize study variables. Binary logistic regression models were used to assess associations between sociodemographic variables, stress-coping behaviors, and self-care behaviors. In a bivariable analysis, variables with p-values less than 0.20 were put into a multivariable logistic regression model. A p-value ≤ 0.05 and an OR with a 95% CI are considered statistically significant associations.Result A total of 432 patients with type II diabetes participated with a response rate of 98%. Stress-coping behavior was observed in nearly half of the patients (51.2; 95% CI; (46.5, 55.6). The study found that stress management behavior was associated with diabetes self-care (X2, 17.7; p0.0001). Patients with good stress management behavior (AOR = 2.0, 95% CI = (1.3, 3.0)), good perception (AOR = 2.3, 95% CI = (1.5, 3.4)), and family support (AOR = 2.3, 95% CI = (1.5, 3.6)) were more likely to conduct diabetes self-care.Conclusion This study shows that stress management behaviors and coping techniques are associated with self-care behavior and lead to significant improvements in diabetes self-care practices. Stress management and coping skills should be included in current systems as a common therapeutic service/treatment and diabetes care practitioners should consider these factors when discussing diabetes self-management during consultations.
Integração Periodontal e Restauradora no Tratamento Estético do Sorriso
Authors: Betanin Uiliane , Machado Débora Lima , Galafassi Daniel , Butze Juliane Pereira
Published: April 2023

Objetivos: O presente estudo tem como objetivo apresentar um caso clínico com planejamento integrado entre a Periodontia e a Dentística Restauradora, visando a melhora estética do sorriso. Relato de caso: Paciente, 21 anos, compareceu à clínica do Centro Universitário da Serra Gaúcha – FSG apresentando queixa estética na região superior pós finalização de tratamento ortodôntico. No exame clínico, foi observado que o formato dental dos incisivos centrais e laterais e perfil gengival poderiam ser alterados. Foi realizado o planejamento conjunto Periodontia-Dentística com proposta de plastia gengival seguida de recontorno com resinas compostas. O enceramento dos modelos com alteração da proporção Altura x Largura dental foi realizado e, um mock up foi apresentado à paciente. Após a aprovação, foram realizados os procedimentos de plastia gengival e recontorno com resinas compostas. Considerações Finais: O tratamento reabilitador associado à gengivoplastia permite uma harmonia estética dental e facial quando traçada um plano de tratamento adequado que alinhe princípios biológicos periodontais com princípios restauradores. Desta forma, a obtenção da harmonia do sorriso eleva a autoestima do paciente, alinhando reabilitação estética e funcional.
Editorial
Authors:   The University of New South Wales
Published: April 2023

Welcome to the first issue of the Australasian Journal of Gifted Education for 2023. Demonstrating the global interest in, and the international impact of, the journal, we have in this issue contributions from scholars based in Jordan, Isreal, and New Zealand, representing various institutions in these countries (i.e., Al al-Bayt University, Tel Aviv University, University of Canterbury, Waikato University, and the New Zealand Ministry of Education). Each of the articles that appear in the issue touch upon different aspects of gifted education, that will no doubt stimulate thought and discussion, and inform practices to more optimally support gifted students in the future.
El Diablo: ¿Mito o realidad?
Authors: Hameau José Antonio
Published: April 2023

This article seeks to address the problem regarding the figure of the devil, that is, if when referring to him we are simply talking about a myth or if we are really referring to a spiritual being with real existence. Our tour begins in Sacred Scripture, passing through the Conciliar Magisterium to finally present the main theological current that denies the existence of the devil.
Physiological Response of a Natural Central Incisor Tooth to Various Loading Conditions: A 3D Finite Element Study
Authors: Nikam Dipti , S. Milani Abbas
Published: April 2023

This study evaluates the influence of different loading angles and the area of loading on the ensuing stress distribution and the physical response of a natural central incisor tooth, using a 3D finite element analysis. The CAD model of the incisor tooth assembly (including enamel, dentin, periodontal ligament, pulp, gingiva and jaw bone) was subject to an external (chewing) load of 100 N, over four different areas and at four different angles along the vertical. It was observed that the tooth experiences high von-Mises equivalent stresses and high bending when the load applied is closer to the incisal edge of the crown. Also, the stresses on the dentin, in general, increased with the increase in the loading angle regardless of the area of loading; with the highest stress (~70 MPa) generated at 45° angle. The percentage change observed in dentin von-Mises stresses was higher than that of enamel when the loading angle was increased from 0° to 45°, because of the higher stiffness of enamel and structural differences in enamel and dentin. The numerical results indicated that applying loads on incisal edge would simulate a severe loading condition for the incisor tooth.
گەشەکردنى عەقڵانى کۆمەڵگەى سیاسی – مەدەنى لەنێوان کانت و هیگڵ دا
Authors: Ahmed Jabar Ismael
Published: April 2023

گەشەکردنى عەقڵانى کۆمەڵگە گرێدراوى هزرینى بیرمەندان و فەیلەسوفانە بۆ پەیوەندییە مرۆییەکان، واتا بە بنەماگرتنى عەقڵ و عەقڵانیەت لە بەرەو پێشچوون و گۆڕانى کۆمەڵگە و دامەزراوەکان و پەیوەندییەکان لەپێناو دەستەبەرى ژیانێکى باشتر. ئاماژە سەرەتاکانى بیرکردنەوە لە گەشەپێدانى کۆمەڵگە بەئاڕاستەى گوزارشتکردن بوو لە گەشەپێدانى بونیادى سیاسی و پەیوەندییە سیاسییەکان، بەتایبەت لاى فەیلەسوفانى گریکى کۆن کە مرۆڤ بونەوەرێکى سیاسییە و سەرقاڵى ڕێکخستنى پەیوەندییە سیاسییەکانیەتى، بەڵام بەگەشەى ژیانى مرۆیی و گۆڕانى بیرکردنەوەکان لەهەمبەر گەشەى کۆمەڵگە، سەرنجدانیش لە ماهیەتى وەرچەرخانى کۆمەڵایەتى و سیاسی کۆمەڵگە گۆڕانکارى بەسەردا هات.
فەیلەسوفانى عەقڵانى بەپشت بەستن بە ڕۆڵى عەقڵ، پرسی گەشەى کۆمەڵگە و کۆمەڵگەى مەدەنى – سیاسییان شرۆڤە کردووە، ئیمانوێڵ کانت پێیوایە کۆمەڵگەى مەدەنى بریتییە لە کۆمەڵگەى سیاسی گەشەکردو ڕووەو کۆمەڵگەى ئامانجەکان لەسەر بنەمایەکى عەقڵانى و ئەخلاقی، واتا لاى کانت کۆمەڵگەى مەدەنى هەر کۆمەڵگەى سیاسییە بەڵام لەچەشنێکى گەشەکردوتر و عەقڵانى و ئەخلاقیتر. هەرچەندە هیگڵیش پشت بە عەقڵ دەبەستێت بۆ شرۆڤەى گەشەى کۆمەڵگە، بەڵام هیگڵ کۆمەڵگەى مەدەنى لە کۆمەڵگەى سیاسی جیادەکاتەوە و کۆمەڵگەى سیاسی بە ڕۆحى ڕەهاى دەوڵەت نەتەوەوە گرێدەدات و ئاستێکى باڵاتری پێدەبەخشێت، هاوکات کۆمەڵگەى مەدەنى وەکو ڕایەڵێک لەنێوان تاکەکان و دەوڵەت وێنادەکات.
هەرچەندە هەردوو فەیلەسوف (کانت و هیگڵ) پشت بە بونیادى عەقڵانى دەبەستن بۆ شرۆڤەى گەشەکردنى کۆمەڵگە، بەڵام بە دوو دەرئەنجامى جیاواز دەگەن، کانت کۆمەڵگەى مەدەنى و کۆمەڵگەى سیاسی وەکو هەمان بوون و لێکەوتى ئەو گەشە کردنە دەبینێت، بەڵام هیگڵ جیاوازى نێوان کۆمەڵگەى مەدەنى و کۆمەڵگەى سیاسی وەکو بەرئەنجامى ئەو گەشەکردنە دەخاتەڕوو.
Evaluation of Sex Hormone in Benign and Malignant Breast Cancer in Iraqi Women
Authors: Hussein Hameedi Ban , Shalash Sultan Ali , Al Hussain Mahdi Ali Abdul
Published: April 2023

Elevated levels of circulating estrogens and androgens are linked to higher breast cancer risk among postmenopausal women; however, little is known about hormone levels within the breast. Hormone concentrations within the breast may not be reflected in the blood and are likely important contributors to breast carcinogenesis. The present study investigated the sex hormone (Estrogen, progesterone, Prolactin and testosterone). Female patients are divided into three groups (Benign, malignant and control). Benign (B)(34 patients) is divided into sub-groups including Benign premenopausal stage (B1)(17 patients) Benign postmenopausal stage (B2) (17 patients) and Malignant (M)(34 patients), Malignant premenopausal stage (M1) (17patients) and Malignant postmenopausal stage (M2)(17patients), and control group (C) include (11) premenopausal stage (C1) and (11) postmenopausal stage (C2). The expression level of soluble sex hormone (Estrogen, progesterone, Prolactin and testosterone) in serum was determined by an ELISA. Technique. The patients attended the Center for Early Detection of Breast Tumor at an oncology teaching hospital in Medical City. The study was conducted on 15/February (2021) to 20/July (2021). The values of Estrogen hormone in premenopausal malignant M1 (34.76 ±4.26 pg/ml) decreased significantly (P≤0.05) in comparison with C1, but it was non-significant in comparison with C2 and B1. M2 (64.28 ±4.17 pg/ml) shows a non-significant increase compared with C1, but it increased significantly with C2, B2 and M1. The values of progesterone hormone B1(12.75 ±3.34ng/ml) and B2( 13.06 ±2.98 ng/ml) was non-significant(P≤0.05) in comparison with C1 (8.17 ±2.87 ng/ml) and C2(6.28 ±2.87 ng/ml).M1 (14.30 ±4.29 ng/ml) and M2 (15.76 ±4.34 ng/ml) show non-significant difference in comparison with C1,C2,B1and B2. The values of Prolactin hormone in the M1(32.07±3.56(µIU/ml)) and M2(29.42±3.16) show non-significant difference(p>0.05) with C1,C2,B1 and B2.levelsTestosterone hormone show a significant in M1(1.462 ±0.11(ng/ml)) increased (p<0.05) in comparison with C1,C2,B1,B2. M2(1.392 ±0.10(ng/ml)) increase significantly(p<0.05) in comparison with C1,C2,B1,B2 and M1. concluded from this study that the levels of estrogen increased significantly in postmenopausal malignant M2 women with breast cancer, and the levels of testosterone hormone significant increase in pre and postmenopausal breast cancer women, the levels of Prolactin and progesterone hormone showed non-significant differences in comparison with other groups.

Keywords: Sex Hormone, Benign, malignant, Breast Cancer,
Innovation Research on the Training Mode of “Double Tutor System” integrating Production and Teaching in Hotel Management Specialty of Higher Vocational Colleges: Stakeholder Perspective
Authors: Shangkun Yao
Published: April 2023

The “double tutorial system” education mode of hotel management major in higher vocational colleges is an important link in the construction of professional teaching staff. The core of this mode is that students get dual guidance from the school and the enterprise in both theory and practice. In the implementation process, we should make full use of school-enterprise resources, set up a double-tutor teaching team, implement incentive measures, and establish a guarantee mechanism, so that both the school and the enterprise can invest high-quality manpower, guaranteed material and financial resources, assume the corresponding responsibility of education, teaching and daily management for the quality of the students cultivated by cooperation, and seek the education effect that the school-enterprise students can win.
Monitorización de infraestructura tecnológica como mejora en centros de datos
Authors: Quintero Martínez Manuel Ignacio , Tovar Balderas Sergio Anduin
Published: April 2023

La infraestructura tecnológica en los centros de datos es una parte vital y debe estar disponible la mayor parte del tiempo para sus usuarios. Para ello muchas actividades se involucran. Una de ellas es la monitorización, que se vuelve crítica tanto en la prevención como en la atención a incidencias de cómputo. En este artículo se presentan algunos elementos a considerar para la incorporación de sistemas de monitorización, así como una breve descripción de Nagios, una de las opciones de licencia libre más populares.
SOME PREDICTIONS OF SCALING RELATIONS: THE CASE OF THE BLACK HOLE IN M87
Authors: Iannella A. L. , Feoli A.
Published: April 2023

In the context of supermassive black holes and their host galaxies, we consider two scaling relations: M• - Reσ3 and M• - MGσ2, to derive three fundamental parameters for the supermassive black hole at the center of M87. In this paper we will get predictions for the efficiency and mass of the black hole, and the temperature of its accretion disk, by comparing them with the respective experimental values.
REFRACTION OF A HERBIG-HARO JET TRAVELLING THROUGH A SHEAR LAYER
Authors: Raga A. C. , Castellanos-Ramírez A. , Cantó J.
Published: April 2023

We study the problem of a radiative Herbig-Haro (HH) jet which travels through a slip surface into a region of side-streaming environment. The interaction with the streaming environment produces an oblique shock that deflects the jet beam. A simple, analytic model for this shock gives the jet deflection as a function of the incidence angle and the environment-to-jet ram pressure ratio. We find that in the case of higher environmental ram pressure, for a high enough incidence angle, the jet stalls and does not penetrate substantially into the streaming environment. We present 3D gas dynamic simulations illustrating the jet deflection and stalling regimes. Possible applications to HH jets showing sudden deflections in their propagation are discussed.
PHOTOMETRIC STUDY OF TWO CONTACT BINARY SYSTEMS AND A DETACHED LATE DWARF + M DWARF COMPONENTS
Authors: Michel R. , Barani C. , Martignoni M. , Acerbi F. , Altamirano-Dévora L.
Published: April 2023

The results of our study of the eclipsing binary systems AF LMi, CzeV188 and CRTS J073333.0+302556 based on new CCD B, V, RC, IC complete light curves, are here presented. The short periods of these systems are confirmed and revised. The light curves were modeled using the latest version of the WilsonDevinney code and, as a result, we found that AF LMi (G3+G9) and CzeV188 (K0+K1) are W UMa-type contact binary systems belonging to the W subclass, showing a shallow degree of fill-out with components in good thermal contact. CRTS J073333.0+302556 is a detached binary system composed by a late dwarf (K8) and an M6 dwarf spectral type components. The asymmetries of the light curves were accounted for with a spot on the surface of one of the component. The absolute elements of the three objects were estimated.
PHOTOMETRIC ANALYSIS OF ECLIPSING BINARIES: VY UMI, RU UMI AND GSC 04364-00648
Authors: Kudak V. , Parimucha Š. , Perig V. , Gajdoš P.
Published: April 2023

We present the photometric analysis of BVR and TESS light curves of three eclipsing binaries, together with their period changes considering archival data and new minima times from our and TESS observations. For the first time we detected wave-like variations with low-amplitude in O − C residua of RU UMi, which can be interpreted as a consequence of the light-time effect caused by the 3rd component with period 7370 days. The period increase detected in the VY UMi system corresponds to mass transfer from the secondary to the primary component. For the GSC 04364-00648 binary system we find quadratic changes on the O − C diagram, which correspond to a period decrease. We cannot make assumptions about their nature, mainly due to short time of observation and uneven coverage of O − C diagram. We also determined the absolute parameter of their components using the photometric solution and GAIA distances.
Para no morir de sed: una etapa constructiva desconocida del sistema hidráulico de Tacuba al Imperial Colegio de Tlatelolco (1581-1582)
Authors: Ramírez López Javier Eduardo
Published: April 2023

El Libro de cargo y descargo del Imperial Colegio de Tlatelolco fue sustraído del Museo Nacional a principios del siglo XX y después pasó desapercibido en la historiografía. Fue en la década de 1990 cuando salió a la luz pública y se vendió a un bibliófilo mexicano, pero en el proceso se pudo fotocopiar. Después de un análisis del manuscrito se localizaron las cuentas referentes a la construcción del caño que surtió agua al Imperial Colegio de Tlatelolco desde Tacuba. Esta etapa constructiva de 1581 a 1582 es desconocida, sin embargo, la información contenida en las cuentas permite conocer los nombres del maestro de obra, mer-caderes y comerciantes que proveyeron los materiales. Por las descripciones en las cuentas, se puede identificar que el sistema hidráulico se realizó por la superficie y de manera subterránea. Fueron fray Bernardino de Sahagún, fray Pedro de Oroz y fray Pedro Serrano quienes supervisaron la obra.
Significant Features and Identification of Heart Disease Prediction by using Data Mining Techniques
Authors: Deepika M , Jayasimman P. , Sanjay G. , Sivaprakash M. , Vignesh T. P.
Published: April 2023

Abstract: In day to day life, there are various factors that affect the mortal heart. Numerous problems are being at a rapid-fire pace and novel heart conditions are fleetly identified. In this stressful of world, Heart, being an essential organ in the body pumps blood through the body for blood rotation essential and its health is to be conserved for a healthy living. The main provocation of doing this design is to provide a heart complaint prediction model for the prediction of circumstances of heart complaints. Further, this exploration study is aimed towards relating the algorithms to relate the possibility of heart complaint in a case. The identification of possibility of heart complaints in a person is complicated process for medical interpreters because it takes times of experience and violent medical tests need to be conducted. In this study, two data mining algorithms such as KNN and SVM classification are addressed and used to develop the prediction system in order to dissect as well as prognosticate the possibility of heart complaint. The main idea of the significant exploration work is to identify algorithms suitable to provide maximum accuracy when classification of normal/abnormal person is carried out. Therefore prevention of loss of lives at an earlier stage is now possible. It is sure that the above algorithms perform better when compared to other algorithms for heart complaint prediction. The design is designed using Python 3.7.
Fatigue Analysis of Front Axle for Automobile Heavy Motor Vehicle
Authors: Lal Manendra Kumar
Published: April 2023

Abstract: The axles in a system must bear the weight of the vehicle as well as any cargo weight. The front axle beam is one of the major parts of vehicle suspension system and it houses the steering assembly as well. About 35 to 40 percent of the total vehicle weight is taken up by the front axle. Corrosion, wear and fatigue are the main causes of failure of mechanical parts. Main failure form of front axle beam is fatigue damage. The axles serve to transmit driving torque to the wheel, as well as to maintain the position of the wheels relative to each other and to the vehicle body. Therefore, the research on the fatigue life has important value. So, proper design and optimization of front axle is extremely crucial to Fatigue strength. The paper focuses on design, analysis and optimization of front axle. The approach in this research paper has been divided into two steps. The First step involves design of front axle by Analytical method. For this, types of forces loads with the help of CAD UNIGRAPHICS NX9.Second step involved further Pre-processing using ANSYS bench work 15.0 and post
Hybrid Water Pumping Control System for Irrigation using Arduino
Authors: Reddy Hanumantha
Published: April 2023

Abstract: There are many water pumping system such as diesel powered, solar photovoltaic, mechanical windmill exists. Few combine solar and wind energy sources to provide better performance and reliability to the existing system. In this paper wind turbine and solar photovoltaic (PV) water pumping array are analyzed separately and are combined as a hybrid system. Large amount of water pumped from the water resources are not effectively used. So a suitable control methodology was also proposed to operate the pump automatically depending on the water availability and the water requirement for crops .The main objective is to provide 1.Advantage of hybrid system over WT or solar PV array separately.2.suitable methodology to prevent water loss. Additionally MPPT system Can be used to improve the efficiency of PV array
Power Generation by Shock Absorber
Authors: Patil Yash , Mali Om , Mahajan Parth , Raut Harsh , Mehata Pranit
Published: April 2023

Abstract: In a country like India, two-wheeler vehicles are predominant over four wheelers. According to data taken from internet, around 20 million two wheelers were sold in 2017/18, as compared to 4 million four wheelers. And this demand keeps on increasing in India. Keeping this mind, a huge potential of energy is being wasted every day. This project is one of the methods to harvest those wasted energy. That’s why this project is under energy recovery. All the major advancements and break through has been done mostly on four wheelers. To name some energy recovery mechanisms, regenerative brakes, regenerative shocks, MGU-H, MGU-K. Even the companies like AUDI and BMW have started launching commercial vehicles which come with energy recovery systems. The main purpose of the dampers is to keep the tires in contact with the ground all the time. Other functions include to absorb the vibrations produced due to irregularities of the surface. This prototype aims to convert these vibrational energies into electricity which otherwise would have been wasted. In a way it can be called Regenerative dampers, which is completely mechanical in nature. This prototype uses a rack and pinion arrangement to convert the reciprocating motion of the bike front fork into a linear motion. The motor is coupled to a DC generator which produces electricity. Our main focus is on two wheelers so, the energy stored can be used to increase the engine efficiency as extra load on alternator is reduced. The aim for this prototype is to produce a current of 0.3A and 12 V (DC), which would be sufficient to charge the batteries and run other auxiliary system of a motorcycle.
Association between Body Image and Psychological Well-being among College students
Authors: Karna Ayushi , Sivaraman Dr. Sruthi
Published: April 2023

Abstract: The purpose of this research was to examine the association of body image in relation to Psychological Well-being among college students using the valid questionnaires i.e. Body Image Scale by Cooper, Taylor, et.al (1987), Psychological Wellbeing Scale by Sisodia and Choudhary (2012). The sample consisted of college students from the age 18 to 25 years from states all over India. The research assessed 80 participants, consisting of 25 males and 55 females. The data was collected offline and online data through stratified random sampling technique. The analysis of the scores was done by Pearson correlation and the results showed that there is a significant relationship between the variables i.e. Body Image and Psychological Well Being showing that there is a negative correlation between the variables. There was no gender difference found in the results. One possible reason for such results could be the societal pressure to conform to unrealistic body standards. This pressure can lead to body dissatisfaction, which has been linked to low self-esteem, depression, and anxiety.