bluuebunny/crossref_metadata_2025 huggingface dataset:
Comunidades bacterianas del intestino de escarabajos peloteros y del suelo en sucesión en la Reserva Tapichalaca
Authors: Román Daniela , Jiménez Heidy , Paucar Cabrera Aura
Published: July 2023

El suelo es un ecosistema importante en el que diferentes especies bacterianas desempeñan un papel fundamental como bioindicadores de su comportamiento ecológico y evolutivo. En el presente estudio se aislaron y caracterizaron morfológicamente comunidades bacterianas de la microbiota intestinal de escarabajos peloteros (Coleoptera: Scarabainae) y del suelo de tres estados de sucesión ecológica (bosque primario, bosque restaurado y pastizal en restauración) de la Reserva Natural Tapichalaca. Se llevó a cabo el aislamiento bacteriano de muestras de suelo y de intestino de escarabajos mediante la inoculación de cultivos mixtos y puros en dos medios de cultivo: Agar Nutritivo (AN) y Agar Tripticasa de Soya (TSA). La identificación morfológica de las colonias bacterianas se realizó a través de la observación de características macroscópicas y la identificación de las células bacterianas mediante Tinción Gram y observación microscópica. Las cepas bacterianas obtenidas en el aislamiento de consorcios bacterianos de las muestras del intestino de los escarabajos y de las muestras de suelo, se asociaron a diferentes posibles géneros bacterianos y se logró concluir que existe variación entre algunos de los géneros identificados en relación con los tres estados de sucesión ecológica. En las muestras intestinales de escarabajos, de los cinco posibles géneros asignados, el género Clostridium se identificó en el bosque primario y Enterobacter en la muestra intestinal de un espécimen del pastizal. En las muestras de suelo, el género Corynebacterium se asoció en la muestra de suelo del bosque primario y Pseudomonas en la muestra de suelo del pastizal.
Role of IL-2/IL-2 receptor in pathogenesis of autoimmune disorders: Genetic and therapeutic aspects
Authors: Rafaqat Sana , Rafaqat Saira
Published: July 2023

Interleukin-2 (IL-2) is an important cytokine that plays a key role in the immune response. The IL-2 receptor (IL-2R) is composed of three subunits, alpha, beta, and gamma, with the alpha subunit having the highest affinity for IL-2. Several studies reported that immune dysregulation of IL-2 may cause tissue injury as well as damage leading to the pathogenesis of various autoimmune diseases such as acute necrotizing vasculitis in systemic lupus erythematosus (SLE), inflammatory synovitis in rheumatoid arthritis (RA), salivary and lacrimal gland dys-function in Sjogren syndrome (SS), obliterative vasculopathy fibrosis in systemic sclerosis (SSc), and inflammatory demyelination in multiple sclerosis (MS). The aim of this review paper was to examine the role of IL-2/IL-2R in various autoimmune disorders, taking into account recent advancements and discoveries, gaps in the current literature, ongoing debates, and potential avenues for future research. The focus of this review is on systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, sjogren syndrome, and multiple sclerosis, which are all linked to the malfunctioning of IL-2/IL-2R. In genetic studies, gene polymorphisms of IL-2 such as IL-2 330/T, IL-2 330/G, and rs2069763 are involved in increasing the risk of SLE. Furthermore, genetic associations of IL-2/IL-2R such as rs791588, rs2281089, rs2104286, rs11594656, and rs35285258 are significantly associated with RA susceptibility. The IL-2 polymorphism including rs2069762A, rs6822844T, rs6835457G, and rs907715T are significant connections with systemic sclerosis. In addition, rs2104286 (IL-2), rs11594656 (IL-2RA), rs35285258 (IL-2RB) gene polymorphism significant increases the risk of multiple sclerosis. In therapeutic approaches, low-dose IL-2 therapy could regulate Tfr and Tfh cells, resulting in a reduction in disease activity in the SLE patients. In addition, elevated sIL-2R levels in the peripheral blood of SLE patients could be linked to an immunoregulatory imbalance, which may contribute to the onset and progression of SLE. Consequently, sIL-2R could potentially be a target for future SLE therapy. Moreover, Low dose-IL2 was well-tolerated, and low levels of Treg and high levels of IL-21 were associated with positive responses to Ld-IL2 suggested to be a safe and effective treatment for RA. Additionally, low-dose IL-2 treatment improves the exocrine glands' ability to secrete saliva in SS-affected mice. Whereas, Basiliximab targets the alpha chain of the IL-2 receptor suggested as a potential treatment for SSc. Also, pre-and post-treatment with Tregs, MDSCs, and IL-2 may have the potential to prevent EAE induction in patients with MS. It is suggested that further studies should be conducted on IL-2 polymorphism in Sjogren syndrome.
ensino de Zoonoses nas disciplinas de Ciências e Biologia na Educação Básica
Authors: De Paula Eric Mateus Nascimento , Vilela Gabriel Brom , Dos Reis Paludo Raquel Loren , De Sousa Campos Eude , Magalhães Mara Rúbia , De Oliveira Elaine Ferreira , De Oliveira Andréa Mara
Published: July 2023

É necessário que as zoonoses e seus impactos na saúde sejam apresentados às crianças e adolescentes ainda durante o período escolar. O objetivo deste trabalho é elencar e discutir as possibilidades do ensino das zoonoses a partir das disciplinas de Ciências e Biologia. Desenvolveu-se uma pesquisa bibliográfica nas bases científicas Scielo, Google Acadêmico, Periódicos Capes, utilizando os descritores: ensino, educação básica e zoonoses. Deve ser usada uma abordagem multidisciplinar envolvendo vários aspectos das doenças zoonóticas. Metodologias como palestras, teatros, jogos, mapas conceituais, cordéis, etc podem ser utilizadas. Educação com ênfase nas zoonoses nas escolas, afeta a saúde de toda a população, pois alcançarão outras escalas da sociedade por meio da difusão do conhecimento nos seus âmbitos familiares e sociais.
REFLEXÕES ACERCA DE ALGUNS EPISTEMÓLOGOS QUE CONTRIBUÍRAM PARA A PERSPECTIVA DE EDUCAÇÃO AMBIENTAL NA ATUALIDADE
Authors: Pinheiro Marcio Mateus Amui , Darsie Marta Maria Pontin , Leão Marcelo Franco
Published: July 2023

A Educação Ambiental é um processo onde pessoas e coletividade constroem seus valores sociais, seus conhecimentos, suas atitudes e suas habilidades aplicadas à conservação do meio ambiente, que é um bem de uso comum e coletivo, essencial à qualidade de vida saudável e sustentável, o que também engloba conceitos de ecologia, ecossistema, autorregulação e desenvolvimento sustentável. O presente texto teve como objetivo refletir sobre as teorias epistemológicas que se relacionam e influenciam na visão atual de Educação Ambiental. Trata-se de um estudo bibliográfico, descritivo e exploratório, cuja abordagem é qualitativa, realizado no primeiro semestre de 2023. Os seguintes aspectos foram observados: principais epistemólogos; a síntese de suas teorias; e como elas contribuíram para a formação da visão da Educação Ambiental que se tem hoje. Nele contém uma breve síntese da teoria Baconiana, do método de Descartes, da Complexidade de Morin, da Teoria Sistêmica de Capra e contribuições de Leonardo Boff. Logo, a reflexão proporcionada por este estudo permite constatar que a visão de mundo e a herança científica de uma sociedade pode sofrer alterações ao longo do tempo.
A GAMIFICAÇÃO COMO PRÁTICA DE ENSINO INOVADORA: UM OLHAR PARA AS TEORIAS EPISTEMOLÓGICAS
Authors: Curvo Evaleis Fátima , Mello Geison Jader , Leão Marcelo Franco
Published: July 2023

A gamificação consiste na  utilização de mecanismos e sistemáticas de jogos para motivar e engajar o participante tornando-o protagonista. Essa pesquisa tem como objetivo refletir sobre as teorias epistemológicas que se relacionam e influenciam na metodologia ativa da gamificação. A pesquisa possui uma abordagem qualitativa e bibliogáfica, de caracter exploratório e descritivo. A  metodologia adotada para a coleta de dados  foi a revisão de artigos, livros e dissertações e no banco de dados da CAPES, do Google Acadêmico e do Scielo. O intuito realizar uma reflexão sobre as teorias epistemológicas que se relacionam e influenciam na metodologia ativa da gamificação, para que seja possível contribuir com aprendizagem do estudante, tornando as aulas  mais prazerosas  e significativas. No que se refere a área cientifica, verificamos que a tecnologia sempre fez parte do nosso cotidiano, até os dia atuais. Portanto, acreditamos ser  possivél  articular as estratégias de ensino com a gamificação, com as teorias epistemologos, favorecendo, assim, a aprendizagem dos estudantes.
Yield and Yield’s Components of Cowpea, Sorghum and Roselle Intercropped at Different Spatial Arrangements
Authors: Jabereldar Abderhim A. , Elemam Afrah B. , Ahmed Sallheldeen E. , Naim Ahmed M. El
Published: July 2023

Intercropping, the cultivation of two or more crops at the same time in the same field, is a common practice in North Korodfan of Sudan in traditional farms of smallholders. This experiment conducted in rainy season (2019/2020) to investigate the effect of intercropping on yield and yield components of cowpea (Vigan unguiculta L), sorghum (Sorghum bicolor L. Moench) and roselle (Hibiscus sabdariffa var. sabdariffa L) intercropped at different spatial arrangements. The experiment consisted of nine treatments: three sole crop of Sorghum Cowpea, and Roselle and eight spatial arrangements of 1:1, 1:2, 2:1, and 2:2 rows of Cowpea with each of Sorghum or Roselle. A randomized complete block design (RCBD) with four replications was used. The results showed that intercropping treatments had significant (P ≤ 0.05) effect on most of the parameters measured on Sorghum, Cowpea and Roselle intercropping. For sorghum: the spatial arrangements 2:2 and 1:1 had the significant highest 100-seed weight (2.9 g) and final seed yield (0.34 ton/ha). For cowpea: the treatment 2:2 had the highest number of pods per plant, 100 seed weight, and shoot dry weight for cowpea. The intercropping 2C:1S had a highest cowpea seed yield (4.2 ton/ha) compared to others spatial arrangements. For roselle the intercropping 2C:2R (two rows of cowpea alternated with two rows of roselle) had the higher number of calyx per plant (19.7) and calyx yield (9.7 g/plant) than the other spatial arrangements. From this study, the practice of planting two rows of cowpea alternating with two rows of sorghum is recommended for farmers under rain-fed sector.
CULTURAL-LINGUISTIC ASPECTS IN TEACHING RUSSIAN AS A FOREIGN LANGUAGE (THROUGH THE CONCEPTUAL EXAMPLE OF “LAWYER”)
Authors: I.A. Nikulina
Published: July 2023

The article examines the concept of "lawyer" from the perspective of teaching Russian as a foreign language (advanced level), analying different aspects of this concept. The data for linguistic and cultural analysis include judicial speeches by F. N. Plevako. In addition, the article points out specific professional traits of the lawyer, helping foreign students to better understand the system of Russian cultural values.
DEM BASED COMPUTATION OF TOPOGRAPHIC SURFACE ROUGHNESS TO REVEAL INCISION IN GILGIT-BALTISTAN,PAKISTAN
Authors: S.R. Ahmad
Published: July 2023

This research investigates interrelationship between landscape evolution and neotectonics in the Gilgit-Baltistan (GB) region based on surface roughness (SR). We analyzed the topographic surface features such as flat area, surface area and surface ratio using Shuttle RadaTopographic Mission-Digital Elevation Model (SRTM DEM) with a spatial resolution of 90 meters. The objective is to make a SR map and to identify areas influenced by neotectonics. The DEM based spatial distribution of slope gradients and slope orientations along with the aspect map were combined to portray the vertical dissection. Lower values of vertical dissection indicate relatively flat topographic basins which generally mean a region of with intermediate slope gradient and slope orientation. Areas with high vertical dissection values correspond to sharp changes in the slope gradients and slope orientations, which could be due to abrupt scrap edges (possibly neotectonic or lithological control). Higher vertical dissection values in GB are wide spread and are oriented SE- NW in Ghanche, Skardu, Hunza, Gilgit and northern Ghizer districts along Karakorum, South Pamirs and Hindu-Kush ranges. While a few higher roughness values are aligned NE- SW in Diamir and Gilgit districts along the Raikot Fault. The surface roughness map is capable of identifying deeply incised valleys, tectonic uplifts and depressions.
CAN MULTIPLE MODELS IMPROVE BAYESIAN'S PERFORMANCE? AN INVESTIGATION USING MCNEMAR'S TEST
Authors: Mtahir
Published: July 2023

Machine learning algorithms have been widely used for classification purposes in a number of research domains; however, very few researches paid any attention to statistically validate the performance of these algorithms for different data. This paper attempted to study the Naïve Bayes algorithm’s performance for dataset of different sizes. Furthermore, a known theory has also been investigated, that building multiple models such as Bagging, Boosting and Stacking tend to improve a classifier’s performance. The analysis has been performed using McNemar’s test; a well known nonparametric statistical test in the medical analysis domain. Results showed that not all ensemble methods work as expected and therefore, needs to be selected carefully. Moreover, the use of McNemar’s test appeared to be simple, but gave statistically valid results.
EFFECT OF SEEDING RATE AND SEED SOAKING DURATION ON PRODUCTIVITY OF RELAY- INTERCROPPED WHEAT IN COTTON
Authors: M. U. Chattha
Published: July 2023

The major problem in cotton-wheat cropping system is delayed harvesting of cotton which results in late planting of wheat. Therefore, a field experiment was conducted on relay wheat in standing cotton that comprised of three different seeding densities (100, 125 and 150 kg ha-1) and four seed soaking durations (0, 6, 12 and 18 hours). The experiment was designed in randomized complete block design with factorial arrangement having three replications. The interactive effect of seed rates and seed soaking duration on emergence count, leaf area index, spikelet’s per spike, grains per spike and grain yield were significant. Wheat sown with seed rate of 150 kg ha-1 and 12 hrs of seed soaking produced significantly higher yield than all other combinations except for 125 kg ha-1seed rate and 12 and 18 hrs of seed soakings. In conclusion, the productivity of relay wheat in standing cotton can be enhanced by using seed rate of 150 kg ha-1 along with seed soaking duration of 12 hours.
EARTHWORM MEAL: A NOVEL NON-CONVENTIONAL FEED INGREDIENT FOR SUSTAINABLE POULTRY PRODUCTION
Authors: M. Arshad  , G. Abbas  , S. Jaffery  , A. H. Hashmi  , I.Hussain  , A. Mustafa  , A. Rehman  , A. Iqbal  , R. Khan  , A. Mahmood  , T. Mahmood  , S. Javed  , R. Mahmood  , M. A. Alvi  , A. U. Haq  , M. H. Ali  , M. S. Rehman  , T.A.Iqba  , U. Mehboob  , S.Khan  , M. M. Saleem  , S. E. Hassan  , Assnain  Munir  , R. A. M. Qureshi
Published: July 2023

The poultry industry is one of the most important/vibrant sectors in the livestock industry. Feed economics is highly important in the production of poultry, especially in intensive farming. Protein intake is the key factor for the sustainable production process and growth rates. Mainly soybean and fish meal is used to fulfill the protein requirements in poultry feed, however, currently, soybean meal and other conventional protein ingredients are facing the problem of shortage supply resultantly increasing in prices. So, there is an urgent need to explore other alternatives and cheaper protein sources. In the past 20 years, amongst different alternative protein sources, private companies and research institutes have focused on the use of algae, insects, and other invertebrates in poultry diets whereas particular attention needs to be paid to the dietary use of earthworms as it is agood and palatable source of protein. Earthworms can be successfully used as an alternative protein source for poultry and aquaculture as an environmentally friendly protein feed ingredient. In this review, we summarize the suitability, productivity, and effectiveness of earthworm meals as an alternative protein ingredient in poultry diets The research has investigated the use of earthworm meal in fish and poultry feed and exhibited an increase in body weight, feed conversion ratio, feed intake, and growth rates in broilers as well as an increase in egg production in layers. The research has shown dietary inclusion level of earthworm meal in the fish diet is successfully up to 25-30% whilst its inclusion level in the broiler diet should not go beyond 15%. Supplementation of earthworm meals in broiler and aquaculture diets may trigger production performances without affecting the quality of the final product. The goal of this review is to deliver the recent scenario of research on earthworm meal; to offer a better understanding of its use as a novel feed ingredient for sustainable poultry production.
Africa Media Review, Volume 13, n° 1, 2005
Authors: Journal system
Published: July 2023

Africa Media Review, Volume 13, n° 1, 2005
Resonant solutions for elliptic systems with Neumann boundary conditions
Authors: Delgado Briceyda B. , Pardo Rosa
Published: July 2023

We consider a sublinear perturbation of an elliptic eigenvalue system with homogeneous Neumann boundary conditions. For oscillatory nonlinearities and using bifurcation from infinity, we prove the existence of an unbounded sequence of turning points and an unbounded sequence of resonant solutions.

See also https://ejde.math.txstate.edu/special/02/d1/abstr.html
Existence of positive global radial solutions to nonlinear elliptic systems
Authors: Padhi Seshadev , Dix Julio G.
Published: July 2023

In this article we obtain global positive and radially symmetric solutions to the system of nonlinear elliptic equations $$ \operatorname{div}\big(\phi_j(|\nabla u|) \nabla u\big) +a_j(x)\phi_j(|\nabla u|) |\nabla u| =p_j(x)f_j(u_1(x),\dots,u_k(x))\,, $$ and in particular to Laplace's equation $$ \Delta u_j(x) =p_j(x)f_j(u_1(x),\dots,u_k(x))\,, $$ where \(j=1,\dots,k\), \( x\in\mathbb{R}^N\), \(N\geq 3\), \(\Delta \) is the Laplacian operator, and \(\nabla\) is the gradient. Also we state conditions for solutions to be bounded, and to be unbounded. With an example we illustrate our results.
See also https://ejde.math.txstate.edu/special/02/p1/abstr.html
Perwujudan Busana Dengan Konsep Pemedal Agung Puri Semarajaya Klungkung
Authors: Wiadnyani Ni Komang , Priatmaka I Gusti Bagus , Paramita Ni Putu Darmara Pradnya
Published: July 2023

Ciri khas keunikan arsitektur Pemedal Agung Puri Semarajaya Klungkung menjadi ide pemantik penciptaan karya busana tugas akhir yang wujudkan menjadi koleksi busana dengan kesulitan bertahap yaitu, Ready to Wear, Ready to Wear Deluxe dan Semi Couture. Pemedal agung Puri Semarajaya diimplementasikan dengan teori analogi dan kata kunci terpilih yaitu, gapura, patung Portugis, batuan (batu bata dan batu padas), keketusan, serta murdha. Penciptaan karya busana ini menggunakan sepuluh tahapan penciptaan Frangipani yang di ambil dari disertasi Tjok Istri Ratna Cora Sudharsana, tahun 2016, yaitu dari ide pemantik (design brief), riset dan sumber (research and sourching), pengembangan desain, sampel (design development), sample, prototype and construction), dan produksi (production), bisnis (business). Hasil dari penciptaan ini diharapkan dapat menambah kepustakaan khususnya dalam bidang Fashion mengenai arsitektur peninggalan Pemedal Agung Puri Semarajaya yang diimplementasikan ke dalam wujud busana Spirituality dengan menggunakan nama brand Titik Awal dan strategi Business Model Canvas (BMC) dalam menjalankan usaha lebih terstruktur.
Heu Meni: Analogi Tanaman Santalum Album Linn Dalam Busana
Authors: Buananda Septalia Anglis , K. Tenaya A.A. Ngurah Anom Mayun , Paramita Ni Putu Darmara Pradnya
Published: July 2023

Cendana merupakan salah satu aset negara dikarenakan kayu yang dihasilkan dapat bernilai sangat mahal. Disamping itu pula cendana menjadi pohon yang banyak diinginkan dari berbagai negara seperti contohnya Cina. Penciptaan karya busana ready to wear , deluxe dan semi haute couture ini ditujukkan untuk mewujudkan busana feminine romantic dengan Bunga Cendana sebagai ide penciptaan dan dilaksanakan bersamaan dengan program Studi/Projek Indenpenden bersama mitra GameLab Indonesia. Bunga Cendana diimplementasikan dengan teori analogi dan kata kunci terpilih yaitu: bunga, lonceng, tipis, merah,dan payung menggarpu. Metode penciptaan yang digunakan yaitu terdiri dari delapan tahapan penciptaan “Frangipani” Desain Fashion dari Dr. Tjok Istri Ratna Cora Sudharsana, tahun 2016 meliputi design brief, research and sourching, design development, sample, prototype, dummy, final collection, promoting, branding, sale, production business. Hasil penciptaan ini diharapkan dapat menambah kepustakaan khususnya dibidang fashion dengan teori analogi Bunga Cendana yang diimplementasikan ke dalam wujud busana feminine romantic
Kompetensi Guru Pendidikan Agama Katolik (Pak) Di Era Milenial Dan Pengaruhnya Terhadap Peningkatan Motivasi Belajar Siswa
Authors: Haru Emanuel
Published: July 2023

Being a teacher in the millenial era is not an easy profession to run. He/ She has to fulfil many demands. He/ She is challenged to have various competencies. Among those that must be fulfilled are competence in technology part. A teacher in the millenial era must be master in using technology tools,such as computer and internet. At least, a teacher must know to operate basic computer programs. By this way, a learning will take place interesting and effectively. For example, a teacher must be able to present His/ Her subject with power point. Besides, a teacher must be able to use e-mail and several other internet programs which are important to support the learning process. By mastering technology, a teacher is expected to explore many sources of knowledge. Therefore, He/ She hasmore knowledge better than students. In addition, a teacher must also prove his professionalism as a teacher by perform all four competencies namely pedagogical, personal, social and professional competencies.

A Catholic Religious Education Teacher must also have such competencies. Apart from those mentioned, one of the typical competencies possessed by Catholic Religious Education Teachers is spiritual competence. By having the competencies as mentioned above, a teacher (including Catholic Religious Education Teachers) is able to increase students’ learning motivation in the entire of learning process in a school.

In this article, the writer presents several studies that prove the influence of the competencies of a teacher (including Catholic Religious Education Teacher) on student learning motivation, especially in this millennial era. These studies concluded that the higher competency of a teacher, cause the students have a good motivation in learning. In contrary, the lower competence of a teacher cause the lower motivation of students to learn.For this reason, the Catholic Religious Education Teacher is expected to be able to apply these competencies in the daily learning process so that students’ learning motivation increases and in the end, the students’ learning achievements also increase.
ORA ET LABORA SPIRITUALITAS DOA DAN KERJA DALAM HIDUP DAN KARYA PAULUS
Authors: Toron Yosef Masan
Published: July 2023

Ora et Labora has been wellknown in Church History as a way of living a life very much based on the Bible. No spiritual life without praying and at the same time no spirituality without labour . Christian spirituality has been woven with prayer life dan with a serious commitment to dayly labour whatsoever.These two dimension was verymuch shown bythe life of St.Paul, the great Apostle and missionary.Paul according to the article is a man of prayer and at the same time a man of labour.Prayer is always a felt need for an apostolic work meanwhile labour is always an anwer for the economic poverty of men and at the same time “homo faber" is a rich illustration for our vows of poverty in the Church.
Konektivitas Pemikiran Politik Islam dengan NKRI Berdasarkan Pancasila (Membaca Pemikiran Munawir Sjadzali)
Authors: Bandur Hironimus
Published: July 2023

One of Muslim figure, Munawir Sjadzali in many of his writings talked about Islam and state administration. This paper explains Sjadzali’s views on Islam and political/state administration historically and their relevance to the NKRI which is based on Pancasila, not based on a particular religion, not a secular state nor but a religious state. Academically, Sjadzali based on the condition of the internal Muslim factions: there was a traditionalistic-integralistic group, there was also a secularistic?partialist group. An exploration history of Sjadzali’s shows that tensions and differences of opinion about Islam and politics among Muslim communities have taken place since the time of the death of the Prophet Muhammad and continues to nowdays. Sjadzali in this paper ignores two extremes and follows one golden mit which is called a symbiotic view, towards Neo-modernism Islam. According to Sjadzali, Islam has a set of principles and ethical values for community and state life as can be found in the Quran, but still has flexibility in its implementation with due regard to the situation of the times and culture. The political system/state administration Islamic when compared to Pancasila, actually there are similarities in principles and enthusiasm.
Bartter Syndrome Presenting with Metabolic Alkalosis: A Case Series
Authors: Mohammed Gulam
Published: July 2023

Bartter Syndrome (BS) is a rare, inherited renal tubulopathy characterised by hypokalaemic, hypochloraemic metabolic alkalosis. Children present with the complaint of polyuria, dehydration, failure to thrive and normal blood pressure despite hyperreninemia and hyperaldosteronism. This is a series of eight children (2 months -1 years of age, 5 males and 3 females children) diagnosed with BS. Mean age of onset was five months with male predominance. Most common presentation was failure to thrive and polyuria. All children showed metabolic alkalosis with hyponatremia, hypokalemia and hypochloremia. Urinary losses of sodium, potassium and chloride were noted in all the eight children. Diagnosis was based on clinical manifestation and electrolyte abnormalities. All children were started on indomethacin and positive response was noted. On follow-up correction of electrolyte abnormalities along with adequate weight gain was seen. Although, it is a rare disease requiring high index of suspicion, but with prompt clinical diagnosis and early treatment, morbidity and mortality can be significantly reduced.
Optimasi Proses EDM Sinking Baja HMD5 di Mesin Makino Edaf3 Laboratorium Produksi Mesin dan Perkakas
Authors: Setiawan Haris , Wahyudin Wawa
Published: July 2023

The EDM sinking process is the process of cutting non-conventional workpieces by using electric sparks that occur when two electric poles are close together, the high temperature of the electric sparks can cause the workpiece particles are eroded and release to become burr in a very small size. The cutting rate in this process is influenced by many factors, including characteristics of the material, type of electrode, cutting parameters, condition of the coolant and  method of spraying the coolant. This study aims to find optimum conditions for the EDM process with  HMD5 steel  workpieces, by using taguchi method wich is effective in making decisions with more than one variable. After all experiments and analysis, the results obtained are spark area level 1 or 50-75, current level 3 or 12A, pulse on time level 2 or 35 ms and pulse off time level 3 or 32 ms, which are the parameters with the most optimum material rete removal. After testing the optimazion result, MRR value increase from 20.26 mm3/min to 33.08 mm3/min and we have conclusion that the taguchi method can help to optimized parameter in EDM process.
REHABILITATION AND MANAGEMENT OF CORAL REEFS IN SOUTHERN QUI NHON BAY (SOUTH VIETNAM)
Authors: Tuan Vo Si , Hoa Nguyen Xuan , Hoang Phan Kim , Ben Hoang Xuan
Published: July 2023

An extensive rehabilitation was practiced during 2002 - 2004 in southernQui Nhon bay of coastal Binh Dinh province where coral reefs had suffered serious degradation due to coral mining, destructive fishing and overfishing. The first experiment indicated that the nearshore reefs in the western part could not be rehabilitated due to environment change during rainy season with large discharge of sediment and freshwater. Transplanted hard corals adapted well in southern part of island Hon Ngang and Hon Nhan with the techniques that used dead coral substratum, concrete plates and revered tubs as theattachments of corals. Survival rate of branch corals Acropora was quite high in dry season (85- 100%) but reduced during rainy season (60-80%). Meanwhile Porites nigrescens presented good adaptation to environment seasonal change. The corals which were fixed with steel sticks on reefplatform had low survival rate due to sediment movement in north-east monsoon. The concurrent site management with strong supports from local government and communities has brought positive effectiveness of reef rehabilitation thank to not only coraltransplantation but also natural recovery. Foliose corals belonging to Montipora,Echinopora. Pachyseris. Echinopora and branch Acropora, Porites play an important role of natural rehabilitation. The activities, however, require hard work and expensive cost as well as sympathy oflocal people.
Genetic diversity and population structure of yam (Dioscorea spp.) from western Ethiopia as revealed by simple sequence repeat markers
Authors: Korsa Fekadu , Feyissa Tileye , Dessalegn Obssi , Mekonnen Tilahun
Published: July 2023

This study examined Ethiopian yam genetic diversity and population
structure using SSR markers. Ten SSR markers were used to analyze a
total of 118 yam genotypes representing six population species that were
collected from four zones in western Ethiopia. A total of 92 alleles
with an overall mean of 9.2 per locus were detected. The average
expected heterozygosity (He) and allelic richness (AR) were 0.88 and
6.30, respectively. All SSR markers were polymorphic and highly
informative, with an overall mean polymorphic information content (PIC)
of 0.87. More ever, all SSR markers discriminated the variations among
the studied yam species. The overall mean expected heterozygosity (He)
and percentage of polymorphic loci within populations were 0.72 and
98.33, respectively. The highest genetic diversity indices were recorded
in the landrace yam populations of D. cayenensis, D. bulbifera, and D.
rotundata species. Analysis of molecular variance (AMOVA) revealed a
moderate but highly significant genetic differentiation (PhiPT=0.100, p
<0.0001). Most of the total genetic variation (91%) accounted
for the within-population variation, leaving only 9% for the
among-population genetic variation. STRUCTURE analysis based on the
Bayesian model weakly inferred two subgroups (K=2), confirming the high
potential of genetic admixtures and close relationships among the
studied yam genotypes, likely due to the presence of high gene flow (Nm=
2.39). D. alata landraces had the least genetic diversity, inferring the
need for strong conservation strategies. This study provided baseline
genetic diversity data for yam breeders to selectively breed for
desirable agronomic qualities and devise conservation measures.
Public Policy, Public Spending, and Nutritional Status of Children Under-5 in Indian States: An Analysis
Authors: Ranjan Priya , Panda Prasant
Published: July 2023

Child malnutrition is a pressing concern in India, impacting physical
and mental development and leading to socio-economic challenges. This
study examines malnutrition prevalence, regional and social disparities,
nutritional expenditure trends, and the impact of nutrition spending on
children under 5, using secondary data from 1997-98 to 2021-22.
Correlation and multiple linear regression are employed in a
cross-sectional framework. The study shows improvements in nutritional
status in low-income states like Madhya Pradesh, Jharkhand, Rajasthan,
Odisha, and Uttar Pradesh. However, Bihar, Chhattisgarh, Jharkhand, and
Madhya Pradesh still face challenges in reducing malnutrition. Rural
areas have higher rates of stunting, wasting, and underweight. Per
capita nutrition spending correlates negatively with stunting and
underweight but positively with wasting and severe wasting. While
nutrition spending alone does not reduce malnutrition, spending on ICDS
and Poshan Abhiyan play a significant role. A one percent increase in
per capita ICDS spending leads to a 9.15 percent reduction in
underweight prevalence, and a one percent increase in per capita Poshan
Abhiyan expenditure results in decreased stunting by 0.07 percent,
wasting by 0.06 percent, and underweight by 0.16 percent. Other factors,
like urbanization, SC-ST population, women’s literacy,
piped-water-availability, sanitation-facilities, and household-size are
significant determinants of malnutrition among children under-5.
Sawflies (Hymenoptera: Symphyta) from Racha and Kakheti regions of Georgia (Sakartvelo)
Authors: Japoshvili George , Haris Attila
Published: July 2023

Thirty-six species of 103 specimens were collected in Racha and Kakheti regions. Faunistic list and zoogeographic analysis are provided. Aprosthema fusicorne (Thomson, 1871), Pristiphora albitibia (Costa, 1859) and Pristiphora beaumonti Zirngiebl, 1957 are new records for the fauna of the country.
PENGEMBANGAN PEMBERIAN CONTOH PENJUMLAHAN BILANGAN BULAT MENGGUNAKAN MULTI REPRESENTASI SEBAGAI MUATAN BAHAN AJAR
Authors: Winda Sari Deni , Rif'at Mohamad , Yundari Yundari
Published: July 2023

This study aims to describe: the feasibility level of teaching materials developed in the form of Student Worksheets, responses, and student learning outcomes after being given learning. The type of research used isResearch and Development (R&D)with the development model of Thiagarajan . The subjects in this study were the seventh grade students of the Asoka Singkawang Private Junior High School, which amounted to 20 people. The instruments used are questionnaires on the feasibility of teaching materials, student response questionnaires, and posttest questions. Data collection techniques: the feasibility of teaching materials was validated by experts, student responses were given a questionnaire, and learning outcomes were given posttest questions. Data were analyzed descriptively quantitatively. The results obtained: the feasibility level of teaching materials is 87.26% with very feasible criteria for use, student response questionnaires are 87% with very high criteria, meaning that student responses are very good, and student learning outcomes are classically fulfilled, namely 85% of students who achieve grades. minimal completeness. Conclusion: the developed teaching materials can be used in learning. Suggestion: further researchers can develop giving examples in learning mathematics and other learning using more diverse representations.
Evidence for liquid-liquid phase separation during the early stages of Mg-struvite formation
Authors: Karafiludis Stephanos , Scoppola Ernesto , Wolf Stephan E. , Kochovski Zdravko , Matzdorff David , Van Driessche Alexander E. S. , Hövelmann Jörn , Emmerling Franziska , Stawski Tomasz M.
Published: July 2023

The precipitation of struvite, a magnesium ammonium phosphate hexahydrate (MgNH4PO4⋅6H2O) mineral, from wastewater is a promising method for recovering phosphorous. While this process is commonly used in engineered environments, our understanding of the underlying mechanisms responsible for the formation of struvite crystals remains limited. Specifically, indirect evidence suggests the involvement of an amorphous precursor and the occurrence of multi-step processes in struvite formation, which would indicate non-classical paths of nucleation and crystallization. In this study, we use synchrotron-based in situ X-ray scattering complemented by cryogenic transmission electron microscopy to obtain new insights from the earliest stages of struvite formation. The holistic scattering data captured the structure of an entire assembly in a time-resolved manner. The structural features comprise the aqueous medium, the growing struvite crystals, and any potential heterogeneities or complex entities. By analysing the scattering data, we found that the onset of crystallization causes a perturbation in the structure of the surrounding aqueous medium. This perturbation is characterized by the occurrence and evolution of Ornstein-Zernike fluctuations on a scale of about 1 nm, suggesting a non-classical nature of the system. We interpret this phenomenon as a liquid-liquid phase separation (LLPS), which gives rise to the formation of the amorphous precursor phase preceding actual crystal growth of struvite. Our microscopy results confirm that the formation of Mg-struvite includes a short-lived amorphous phase, lasting >10 seconds.
Legal Consequences of Implementing Ijarah Contracts in Sukuk Issuance
Authors: Linda Sisi ade linda , Iwan Setiawan  , Muhamad Izazi Nurjaman
Published: July 2023

Currently, the development of the Islamic capital market shows rapid progress, as evidenced by the increase in the index in the JII (Jakarta Islamic Index) list. The presence of Islamic financial products such as sharia invests is considered to be a solution to investment problems that have occurred recently. One of the islamic financial products that is developing today is sukuk. Today sukuk has become one of the strongest elements in the Islamic economy. one type of sukuk in Indonesia is the ijarah sukuk. The research method used in this study is a qualitative method with a descriptive approach, which collects data related to sukuk in the ijarah contract taken from sources such as books, journals, skrpisi, thesis, and other related sources. The results showed that the Ijarah sukuk is a type of letter that indicates an ownership of an asset, for which the asset is leased. This sukuk is one type of letter that can be traded because the sukuk gives the right to the holders to get money from the lease proceeds as well as the right to transfer ownership without any taking rights from the tenant.
ANALISIS LITERASI ABAD KE – 21 BACA TULIS DI SEKOLAH DASAR SE-KECAMATAN KAMPUNG RAKYAT LABUHAN BATU SELATAN
Authors: Qori Muhammad Al , Rohana Rohana
Published: July 2023

ABSTRAKPenelitian ini bertujuan menganalisis penerapan literasi baca tulis di sekolah dasar di kecamatan kampung rakyat Labuhan Batu Selatan. Jenis penelitian kualitatif dengan pendekatan deskriptif Kulitatif. Sumber data primer (jumlah sekolah di kecamatan kampung rakyat kabupaten labuhan batu selatan adalah 39 sekolah.Teknik pengambilan sampel menggunakan rumus slovin n =   = 99 subjek siswa dan informasi kunci kepala sekolah. Instrument penelitian yang digunakan yaitu angket dan wawancara, analisis data melalui reduksi, analisis, dan penarikan kesimpulan. Hasil persentase tersebut menunjuknan bahwa 24,97% telah menunjukkan gemar membaca hal ini dapat dilihat bahwasannya penerapan keterampilan membaca dan menulis yang di laksanakan sekolah dalam satu minggu sekali, selain gemar membaca yang menunjukkan bahwa 29,64 % siswa membaca kreatif dalam halnya membaca kreatif ini lebih di sukai oleh siswa karena mereka bisa mengekspresikan pada saat membaca.dan persentase pengembangan diri 69,86% lebih banyak siswa yang menyukai pengembangan diri di karenakan siswa bias mengembangkan dan mengekspresikan diri mereka sesuai dengan keahliannya masing-masing.Kata Kunci: Literasi Membaca dan Menulis, Membaca Menyenangkan, Membaca Kreatif, Pengembangan Diri ABSTRACTThis study was conducted with the intention of gaining an overall view of the reading abilities taught in schools, particularly at the elementary level in the Kampung Rakyat, South Labuhan Batu in Malaysia. qualitative research method was employed by a descriptive approach. The number of schools in the Kampung Rakyat, South Labuhan Batu district is 39 as primary data source for the investigation. The sampling technique uses the slovin formula      99 student subject and principal key information. In this research, the researcher employed questionnaires and interviews, and the researcher analyzed the data by first reducing it, then analyzing it, and then drawing conclusions from it. According to the findings of this percentage, 24.97% of people have demonstrated a preference for reading. In addition to having a love for reading, which demonstrates that 29.64% of students read creatively in terms of creative reading, it can be noted that the school applies reading and writing skills once a week. This is in addition to the fact that the school has a weekly reading and writing class increasingly popular with kids since reading allows them to express themselves, and the number of students who prefer self-development has increased by 69.86% because students are able to grow and express themselves according to their particular competence.Keywords: Reading and Writing Literacy, Fun Reading, Creative Reading, Self-Development
Pengujian Fungsionalitas dan Kualitas Website Wisata Kotawaringin Timur Menggunakan Metode Black Box dan Standar ISO
Authors: Minarni Minarni , Sigit Sigit
Published: July 2023

Penelitian ini bertujuan untuk menguji fungsionalitas dan kualitas aplikasi website rekomendasi wisata Kotawaringin Timur dengan menggunakan metode black box dan standar ISO. Pengujian dan implementasi website wisata ini dilakukan juga menggunakan Skala Likert sebagai instrumen survey untuk menentukan tingkat kepuasan responden. Adapun responden penelitian ini meliputi Dinas Kominfo Kotim, Dinas Kebudayaan dan Pariwisata Kotim, mahasiswa, pelajar, dan masyarakat umum Kotawaringin Timur. Dinas Komunikasi dan Informatika (Kominfo) Kotawaringin Timur bertanggung jawab sebagai pihak yang mengelola hosting dan domain website wisata ini, sedangkan Dinas Kebudayaan dan Pariwisata Kotawaringin Timur sebagai pengguna serta pengelola websitenya . Oleh karena itu, website ini sangat perlu diuji fungsionalitas dan kualitasnya demi optimalnya pemanfaatan website sebagai penyedia informasi bagi masyarakat serta wisatawan. Faktor yang diujikan meliputi functionality, usability, efficiency dan portability. Hasil dari pengujian website ini menunjukkan bahwa website wisata memiliki hasil yang baik dalam hal functionality, usability, efficiency, dan portability. Namun, masih terdapat kekurangan dalam hal keamanan atau security pada bagian functionality.
Recenzja: Horka – łużycka Golgota służby zdrowia 2. Armii Wojska Polskiego.
Authors: Woszczerowicz Zuzanna Alicja
Published: July 2023

Recenzja monografii pt. Horka – łużycka Golgota służby zdrowia 2. Armii Wojska Polskiego autorstwa Krzysztofa i Zbigniewa Kopocińskich.
Cutaneous Syncytial Myoepithelioma: A Unique Variant Worth Recognizing
Authors: Mahmood Muhammad N.
Published: July 2023

Cutaneous syncytial myoepithelioma is a recently characterized variant of cutaneous myoepithelioma with a distinct histopathological and immunohistochemical profile. It is more common in men and predominately involves upper and lower extremities. Microscopically, it is a dermal tumor with a characteristic solid syncytial growth pattern displaying positivity with EMA and S100 immunohistochemical stains. Lately, EWSR1-PBX3 fusion has been documented in a vast majority. Although it follows a benign clinical course, its histopathological differential diagnosis includes clinically aggressive neoplasia. This contribution summarizes the derivation, clinical presentation, histopathological and immunohistochemical features, molecular genetics, pertinent differential diagnosis, and behavior of this unique cutaneous appendageal tumor.
The Ethical Treatment of Impaired Neonates: Evaluating the Werdinig-Hoffman Case at Dankook University Hospital
Authors: McGuire John Michael , CHEONG Yoo-seock
Published: July 2023

Under what circumstances, if any, is it ethically acceptable to withhold ordinary medical care from babies born with severe disabilities? Doctors at Dankook University Hospital in Chonan, South Korea were forced to confront this question in November 1999 when a 15 year-old girl, who had recently given birth to a baby with Werdinig-Hoffman disease, requested physicians to withhold basic life-sustaining treatment from her baby. Cases such as this one raise several difficult ethical questions, chief among which are the following two. First, who should decide whether or not to withhold life-sustaining treatment from an impaired neonate: the baby’s parents, the attending physicians, or someone else? Secondly, what considerations should be relevant to this decision?
In this paper we answer these two questions and, in so doing, provide an ethical framework that can be used by physicians in making and evaluating decisions regarding the treatment of impaired neonates. After providing this framework, we then apply it to evaluate the decision that was made in the Dankook case.
The ethical framework that we argue for in this paper is a best-interests position similar to that which has been proposed by Robert Weir. Our defense of this position is based on the idea that the principles and practices governing pediatrics in general should also govern the treatment of impaired neonates. Since the principle of beneficence is the guiding principle in pediatrics, in contrast to adult medicine which is governed chiefly by patient autonomy, the principle of beneficence should also be the guiding principle for physicians treating impaired neonates. A consequence of this, we argue, is that it is physicians, rather than parents, that should be the primary decision-makers with respect to the question of whether or not to withhold life-sustaining treatment from an impaired neonate.
Furthermore, we argue that this decision is one that should be based only on considerations of what is in the baby’s best interests, where that is understood from a strictly medical point of view. In particular, we claim that the emotional or financial stability of the baby’s family should not be treated as relevant in the physician s decision-making process.
EU Policy and Legislation on Stem Cell Research
Authors: KWON Ivo
Published: July 2023

EU policy on the research of the human embryo and stem cell is based on the 1997 Convention - Convention for the Protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine : Convention on Human Rights and Biomedicine. The purpose of this convention is to protect the dignity and identity of all human beings without discrimination, respect for their integrity and other rights and fundamental freedoms with regard to the application of biology and medicine. Applying this convention's view to the human embryo and stem cell research, 1) the human embryo research can only be permitted only if it protect the embryo for the purpose of the health and medicine. 2) Making human embryo is prohibited by any method-IVF or SCNT technique. 3) Other stem cell resources(adult stem cell, cord blood stem cell, etc) can be used under the condition of full informed consent without any financial interest of the donor. 4) In all cases, the privacy and human right as well as health of all related persons should be guaranteed.
As a result, the research on the human embryo and stem cell has not been done actively except in few country. But now most member states permit stem cell research using spare embryo, but prohibit therapeutic cloning by SCNT. However EU itself has failed to agree with to fund the scientific research on stem cell using spare embryo. It is hardly to say the decision on stem cell research in the future by EU, but EU will continue to stress on the basic human right, social justice and human freedom in the field of biotechnology and its applications.