bluuebunny/crossref_metadata_2025 huggingface dataset:
A Value Modeling Approach for Product Development Processes and Supply Chain Management
Authors: Yadav Salik , Keshar Anupam , Shukla Nagesh
Published: December 2022

This research presents a quantifiable value modeling approach for tracking and optimizing value addition at different stages of the product development process (PDP) and supply chain management (SCM). While there is a vast abundance of papers in the literature harping on the need to maximize the value, especially in lean thinking context, in PDP and SCM, there is a dearth of propositions on how to quantitatively measure and optimize value at each stage of product development and supply chain. This paper presents a multi-dimensional value modeling approach that incorporates parameters and variables from different stages of PDP and SCM by mathematically mapping them on to two macroscopic metrics, namely Product Information Evolution and Risk Reduction. These two metrics are in turn modeled by incorporating value attribute variables such as performance, risk, schedule, cost, form, fit, function and timeliness from different stages of PDP-SCM such as customer needs ideation, product functions, inventory management, logistics management and product delivery. The efficacy of the proposed model was tested by utilizing it to measure value additions at different stages of PDP-SCM as well as the total value addition for an ordinance disposal (OD) robot product family, once developed and supplied using traditional production method and once using lean production method, with the underlying axiom being the lean method will result in higher value. To ensure a fair and accurate comparison, both production methods used the proposed mathematical value model and worked toward maximizing total value using nonlinear programming. The results showed that lean PDP-SCM method added higher value at each of the stages as well as total value when compared to the traditional PDP-SCM method thus establishing the proposed value model as a viable mathematical way to measure value. While the proposed value model passed test of efficacy against the lean axiom, further research is needed to test it against other established axioms to establish it as a robust mathematical way to measure value in PDP-SCM.
Convenient syntheses of phthalocyanine and tetrabenzotriazaporphyrin (TBTAP) mono-alkynes; unhindered building blocks for click chemistry and beyond
Authors: Aljuhani Ateyatallah , Díaz-Moscoso Alejandro , Cammidge Andrew N.
Published: December 2022

Unsymmetrical phthalocyanines and related macrocycles are often desirable for covalent construction or the self-assembly of more complex architectures. Terminal alkynes are versatile in this regard because they are amenable to cross-coupling via Sonogashira-type reactions, alkyne-alkyne coupling via Glaser-type couplings, and triazole formation via Click reaction with azides. Here we describe two complementary syntheses to conveniently add a single alkyne onto the phthalocyanine peripheral position and onto the meso-phenyl group of an (aryl)tetrabenzotriazaporphyrin, here providing a remote link point that is insulated from the macrocycle.
Three-Dimensional Vibrational Characteristics of Functionally Graded Rotating Microbeams Based on the Higher-Order Refined Shear Deformation Theory
Authors: Jin Songye , Zhang Bo , Shen Huoming , Wang Yuxing , Zhang Wuyuan
Published: December 2022

This study establishes a novel three-dimensional dynamic model for functionally graded rotating microbeams simultaneously considering flapwise and chordwise shear effects based on a refined shear deformation theory and the modified couple stress theory. Five kinematic variables are introduced to describe the rotating microbeam’s axial, flapwise, and chordwise motions using a higher-order refined shear deformation theory. The related strain energy and kinetic energy functionals are discretized by the assumed mode method. Applying the Euler–Lagrange variational formulation, the governing equations for the rotating microbeam are obtained. Selective examples are provided to demonstrate the convergence and effectiveness of the proposed model. Finally, the impacts of slenderness ratio, rotation speed, material index, material length scale parameter (MLSP), and Poisson’s effect on the vibrational characteristics of the microbeam are examined. Numerical results indicate that the mode shape transition and frequency loci veering phenomena could easily occur under slight changes in the above factors when dense modes appear in the rotating microbeam; moreover, there is a positive/negative competitive relationship among the effects of rotation speed, MLSP, and shear deformation; Poisson’s effect seriously affects the coupling between axial and non-axial motions of the rotating microbeam. The results obtained are expected to provide data accumulation and methodological basis for the failure analysis and vibration shape determination of micro air vehicles.
Design of an IoT platform for data analytics based fault detection and classification in solar PV power plants using CFKC and ODENN
Authors: Raj Shweta , Sivagnanam S. , Kumar Kevin Ark
Published: December 2022

New policies are commenced all over the globe to diminish the use of fossil fuels, which gives rise to the augmented utilization of solar energy (SE). The photovoltaic (PV) system’s performance is extremely environmental variables reliant. Long-range transmission of SE is incompetent as well as complex to carry in the PV system. It can be affected by disparate sorts of faults, which cause severe energy loss all through the system operation. Thus, it is vital to incessantly monitor the solar PV (SPV) system to detect as well classify the faults by preventing energy losses. The IoT applications in SE production engage sensor devices that are fixed to the generation, and transmission, together with distribution equipment. These devices assist in monitoring the operation of the SPV power plant (SPVPP) system remotely in real-time. Presenting a new algorithm that can perform fault detection and classification in a PV system to a higher level of accuracy is the major contribution of this work. Thus, this work designs as well as develops an IoT platform for carrying out analytical tasks that can analyze data generated as of IoT operating systems to detect as well as classify faults in the SPVPP. Initially, the data collected from the dataset is pre-processed in which data duplication is performed using Hadoop distributed file system (HDFS) and then the fault is detected from the pre-processed data using the cosine function based k-means clustering (CFKC) technique in the SPV system. Finally, the obtained fault data is fed into the optimized deep learning centered ENN (ODENN) method which classifies the faults. The proposed techniques detect as well as classify the faults effectively that are experimentally proved by means of comparing them with the prevailing techniques, namely ENN, ANN and SVM, along with KNN in terms of some quality measures. The obtained results for ODENN showed an accuracy of 98.99%, specificity of 97.6%, and a sensitivity of 97.02%.
Agency and Amplification
Authors: Gauthier Robert P. , Pelletier Catherine , Carrier Laurie-Ann , Dionne Maude , Dubé Ève , Meyer Samantha , Wallace James R.
Published: December 2022

Computational techniques offer a means to overcome the amplified complexity and resource-intensity of qualitative research on online communities. However, we lack an understanding of how these techniques are integrated by researchers in practice, and how to address concerns about researcher agency in the qualitative research process. To explore this gap, we deployed the Computational Thematic Analysis Toolkit to a team of public health researchers, and compared their analysis to a team working with traditional tools and methods. Each team independently conducted a thematic analysis of a corpus of comments from Canadian news sites to understand discourses around vaccine hesitancy. We then compared the analyses to investigate how computational techniques may have influenced their research process and outcomes. We found that the toolkit provided access to advanced computational techniques for researchers without programming expertise, facilitated their interaction and interpretation of the data, but also found that it influenced how they approached their thematic analysis.
Design Justice in Practice
Authors: Hedditch Sonali , Vyas Dhaval
Published: December 2022

While varying degrees of participatory methods are often explored by the HCI community to enable design with different user groups, this paper seeks to add weight to the burgeoning demand for community-led design when engaging with diverse groups at the intersections of marginalisation. This paper presents a 24-month-long qualitative study, where the authors observed a community-based organisation that empowers refugee and migrant women in Australia through making. We report how the organisation led its own process to pivot from face-to-face to online delivery during the COVID-19 pandemic, analyzing the design and delivery of an app and the intersectional challenges faced by the women as they learnt to navigate online making. This paper expands feminist intersectional praxis in HCI to new contexts and critiques the positionality of researchers in this work. It contributes to the literature on design justice, providing an exemplar of how community-led design more effectively dismantles the compounding constraints experienced by intersectional communities. This paper also argues that the ethos of care and safe spaces, which are central to black feminist thought, are vital to community-led design and underpin the 10 design justice principles when executed in practice.
Designing Motion: Lessons for Self-driving and Robotic Motion from Human Traffic Interaction
Authors: Brown Barry , Laurier Eric , Vinkhuyzen Erik
Published: December 2022

The advent of autonomous cars creates a range of new questions about road safety, as well as a new collaborative domain for CSCW to analyse. This paper uses video data collected from five countries - India, Spain, France, Chile, and the USA - to study how road users interact with each other. We use interactional video analysis to document how co-ordination is achieved in traffic not just through the use of formal rules, but through situated communicative action. Human movement is a rich implicit communication channel and this communication is essential for safe manoeuvring on the road, such as in the co-ordination between pedestrians and drivers. We discuss five basic movements elements: gaps, speed, position, indicating and stopping. Together these elements can be combined to make and accept offers, show urgency, make requests and display preferences. We build on these results to explore lessons for how we can design the implicit motion of self-driving cars so that these motions are understandable - in traffic - by other road users. In discussion, we explore the lessons from this for designing the movement of robotic systems more broadly.
HoloMentor
Authors: Seo Jwawon , Avellino Ignacio , Rajasagi Damaruka Priya , Komlodi Anita , Mentis Helena M.
Published: December 2022

The introduction of Augmented Reality (AR) Head Mounted Displays (HMDs) in collaboration between remote and local workers, introduces new challenges given that camera views are now mobile. We introduce HoloMentor, an AR HMD-based collaborative system designed for remote instruction over live mobile views during physical tasks. Through Actionport, we provide a world-stabilized area where remote helpers can dynamically place a pointer and annotations on the physical environment. Through Actionpad, we provide an indirect input mechanism with an absolute position to the Actionport. We show how these innovations worked for participants engaged in a remote instructional task and how they supported effective and efficient communication. Finally, we provide the next steps for addressing AR on mobile views for remote instruction.
Integrating Real-Time and Non-Real-Time Collaborative Programming
Authors: Ma Yifan , Qi Batu , Xu Wenhua , Wang Mingjie , Du Bowen , Fan Hongfei
Published: December 2022

Real-time collaborative programming enables a group of programmers to edit shared source code at the same time, which significantly complements the traditional non-real-time collaborative programming supported by version control systems. However, one critical issue with this emerging technique is the lack of integration with non-real-time collaboration. Specifically, contributions from multiple programmers in a real-time collaboration session cannot be distinguished and accurately recorded in the version control system. In this study, we propose a scheme that integrates real-time and non-real-time collaborative programming with a novel workflow, and contribute enabling techniques to realize such integration. As a proof-of-concept, we have successfully implemented two prototype systems named CoEclipse and CoIDEA, which allow programmers to closely collaborate in a real-time fashion while preserving the work's compatibility with traditional non-real-time collaboration. User evaluation and performance experiments have confirmed the feasibility of the approach and techniques, demonstrated the good system performance, and presented the satisfactory usability of the prototypes.
Looking Past the Miracle Box
Authors: Weibert Anne , Ahiataku Sandra Juliet , Dawuni Godson Rashid , Aal Konstantin , Misaki Kaoru , Wulf Volker
Published: December 2022

This paper focuses on tools to approach the practices inherent to the formal and informal e-waste value-chains in Ghana. Our series of field trips and interviews with e-waste collectors and scrap workers, repairers and retailers at their respective workplaces, as well as with domestic electronics users captured a situation in flux, where local authorities had implemented their decision to demolish the Agbogbloshie scrapyard site in Accra in July 2021 and relocate the workplaces within the city. In this situation, our exploratory perspective on tools and practices serves as a lense to identify possibilities of socio-technical support for repairing and upcycling and related community building.
On Composing Finite Forests with Modal Logics
Authors: Bednarczyk Bartosz , Demri Stéphane , Fervari Raul , Mansutti Alessio
Published: December 2022

We study the expressivity and complexity of two modal logics interpreted on finite forests and equipped with standard modalities to reason on submodels. The logic 

\(\mathsf {ML} ({\color{black}{{\vert\!\!\vert\!\vert}}})\)

extends the modal logic K with the composition operator 

\({\color{black}{{\vert\!\!\vert\!\vert}}}\)

from ambient logic whereas

\(\mathsf {ML} (\mathbin {\ast })\)

features the separating conjunction 

\(\mathbin {\ast }\)

from separation logic. Both operators are second-order in nature. We show that 

\(\mathsf {ML} ({\color{black}{{\vert\!\!\vert\!\vert}}})\)

is as expressive as the graded modal logic 

\(\mathsf {GML}\)

(on trees) whereas 

\(\mathsf {ML} (\mathbin {\ast })\)

is strictly less expressive than 

\(\mathsf {GML}\)

. Moreover, we establish that the satisfiability problem is
Tower
-complete for 

\(\mathsf {ML} (\mathbin {\ast })\)

, whereas it is (only) 
AExp

Pol

-complete for 

\(\mathsf {ML} ({\color{black}{{\vert\!\!\vert\!\vert}}})\)

, a result that is surprising given their relative expressivity. As by-products, we solve open problems related to sister logics such as static ambient logic and modal separation logic.
Effect of some Cultivation Factors and Extraction Methods on Terminalia Catappa L. Seed Oil
Authors: Nguy Le Hong , Hien Ly Thi Minh , Dao Dong Thi Anh
Published: December 2022

Terminalia catappa L. is a common tropic tree for shade and ornament in many countries. Recently, Terminalia catappa L. seed oil has been considered as a new oleaginous seed for dietary and biofuel production. In this study, ripe Terminalia catappa L. fruits originated in Vietnam were collected and seed oil extracted. In our experiment conditions, the effect of tree location, tree age, and annual harvest time on seed weight and seed oil content was investigated. As results, the seeds at the eastern site of the ground obtained not only the biggest size (3.607 g) but also contained the highest oil mass percentage (56.38%). The suitable annual harvesting time for the good seed quality was from March to April. In addition, the Terminalia catappa L. seeds for oil extraction began being harvested in the fourth year with 55.88% oil content compared to 55.99% of the five and six-year-old and trees. After seed drying, the seed oil was extracted by five different methods including cold screw pressing, hot screw pressing, hydraulic pressing, and solvent extracting, and combining method (cold screw pressing then solvent extraction of oil cake). Among the physical methods, cold screw pressing observed the highest oil yield of 77.32%, and the good oil quality was obtained with low free fatty acid (0.550% oleic acid), low acid value (1.080 mg KOH/g oil), and low peroxide value (1.240 meq O2/kg oil). However, the combination of cold screw pressing and cake oil extracting by solvent increased the oil yield by 14.61%. The saponification values fluctuated between 196 to 197 mg KOH/g oil, while the iodine values were in the range of 77.00 and 79.89 g I2/kg oil.
Physiological Alterations due to Hepatotoxicity and the Protective Role of Cleome viscosa Linn Seed Extract in Experimental Animals
Authors: Donkor Addai-Mensah , Donkor Martin Ntiamoah , Ahenkorah Benjamin , Asare-Konadu Kwadwo Asante , Asiedu Emmanuel , Mosobil Richard
Published: December 2022

Liver ailment is a key public health menace, principally in developing nations. Quite a lot of medicinal florae have been identified to have liver shielding activities. The current study was designed to assess in vitro antioxidant and in vivo hepatoprotective activities of seed extracts of Cleome viscosa Linn. (Capparaceae). Phytochemical screening of C. viscosa seed ethanol extract was carried out. Free radical scavenging activity of crude seed extract of the plant was conducted using the DPPH assay method. DNA damage protection potential of the crude seed extract was carried out using extract of the genomic DNA nicking assay. Hepatoprotective activity of the crude seed extract of the plant was carried out based on CCl4-induced liver damage in Wister albino rats. Serum biomarkers (aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and total protein (TP)) were evaluated to find out the effect. Histopathological scrutiny was also carried out for all groups of rats to further confirm the discoveries. The phytochemical screening was positive for alkaloids, flavonoids, saponins, steroids, terpenes, tannins, and phenolic compounds in the seed extract. The antioxidant assay revealed that the ethanol crude extract of C. viscosa exhibited free radical scavenging activity with IC50 value of 17.82 ± 0.32 μg/mL, and this was further confirmed by the DNA damage protection activity. Pretreatment of the rats with the crude extract of C. viscosa significantly reduced ALP (p < 0.05). The hepatoprotective activity of the seed extract was confirmed by histopathological studies. From this study, it can be concluded that the crude seed extract revealed antioxidant and hepatoprotective activities. For that reason, in the future, oral intake of C. viscosa seed extract as an adjunct natural therapy may be worthwhile to protect against liver failure-mediated inhibitory effects on reproductive function.
Coordinated Control of ESP-SAS System Considering Roll
Authors: Wang Peng , Ge Yuan , Cao Shanggui , Han Chao , Yang Ping , Zhang Zhichao
Published: December 2022

To improve the antiroll ability of the vehicle, considering the coupling characteristics of vehicle dynamics and tire force, this paper proposes a vehicle active antiroll strategy based on an electronic stability program and semiactive suspension (ESP-SAS) coordinated control. According to the motion characteristics of the electronic stability program (ESP) and semiactive suspension (SAS), the fuzzy controller based on the ESP module and the proportion integration differentiation (PID) controller based on the SAS module are designed, respectively. Through the adjustment of ESP yaw moment and the timely matching of SAS damping force, the antiroll performance of the vehicle is optimized. At the same time, due to the coupling characteristics between the two, a coordinated controller is designed to minimize the transfer of tire dynamic load. The proposed strategy is simulated and verified by Fishhook test conditions. As is shown from the results, with a good effect on the control of vehicle roll risk, the proposed coordinated control strategy can not only effectively reduce the body roll angle but also improve the operation stability of the vehicle.
Ridge Regression for Functional Form Identification of Continuous Predictors of Clinical Outcomes in Glomerular Disease
Authors: Rubin Jeremy , Mariani Laura , Smith Abigail , Zee Jarcy
Published: December 2022

Introduction: Penalized regression models can be used to identify and rank risk factors for poor quality of life or other outcomes. They often assume linear covariate associations, but the true associations may be nonlinear. There is no standard, automated method for determining optimal functional forms (shapes of relationships) between predictors and the outcome in high-dimensional data settings. Methods: We propose a novel algorithm, ridge regression for functional form identification of continuous predictors (RIPR) that models each continuous covariate with linear, quadratic, quartile, and cubic spline basis components in a ridge regression model to capture potential nonlinear relationships between continuous predictors and outcomes. We used a simulation study to test the performance of RIPR compared to standard and spline ridge regression models. Then, we applied RIPR to identify top predictors of Patient-Reported Outcomes Measurement Information System (PROMIS) adult global mental and physical health scores using demographic and clinical characteristics among N = 107 glomerular disease patients enrolled in the Nephrotic Syndrome Study Network (NEPTUNE). Results: RIPR resulted in better predictive accuracy than the standard and spline ridge regression methods in 56–80% of simulation repetitions under a variety of data characteristics. When applied to PROMIS scores in NEPTUNE, RIPR resulted in the lowest error for predicting physical scores, and the second-lowest error for mental scores. Further, RIPR identified hemoglobin quartiles as an important predictor of physical health that was missed by the other models. Conclusion: The RIPR algorithm can capture nonlinear functional forms of predictors that are missed by standard ridge regression models. The top predictors of PROMIS scores vary greatly across methods. RIPR should be considered alongside other machine learning models in the prediction of patient-reported outcomes and other continuous outcomes.
Obesity-Induced Memory Deficits in Female Rats Are Oestrous Cycle Dependent and Linked to Impaired Brain Kynurenine Pathway Metabolism
Authors: Mezo-González Carla Elena , García Santillán Juan Antonio , Reyes-Castro Luis Antonio , Gourdel Mathilde , Croyal Mikaël , Bolaños-Jiménez Francisco
Published: December 2022

Introduction: Obesity is associated with impaired learning, but the mechanisms underlying this cognitive dysfunction are poorly understood. Moreover, whether obesity-induced learning deficits show sexual dimorphism remains controversial. Females are believed to be protected from cognitive decline by oestrogens. These hormones enhance the expression of tryptophan hydroxylase 2, the rate-limiting enzyme in the transformation of tryptophan (Trp) into serotonin which plays a significant role in learning and memory. However, several learning-regulating compounds also arise from Trp metabolism through the kynurenine pathway (KP), including kynurenic acid (KA), xanthurenic acid (XA), and NAD+. The present study aimed to determine the involvement of the KP of Trp metabolism in the regulation of learning in control and obese female rats. Methods: The learning capabilities of control and obese rats were evaluated using the novel object recognition test. Trp and Trp-derived metabolites were quantified in the hippocampus and frontal cortex by ultra-performance liquid chromatography-tandem mass spectrometry. Results: Control rats in proestrus/oestrous performed better than their control mates in metestrus/dioestrus. Likewise, while control and obese rats in dioestrus/metestrus did not show differences in learning, obese rats in proestrus/oestrous displayed decreased memory capacity along with decreased Trp concentration and reduced KA, XA, and NAD+ production in the hippocampus. These neurochemical alterations were associated with impaired expression of mRNAs coding for key enzymes of the KP. Conclusion: The results presented here indicate that the deleterious effects of obesity on learning are closely related to the oestrous cycle and associated with an impairment of the KP of Trp metabolism.
A lógica de dupla estigmatização social de crianças e adolescentes em situação de rua em Capitães da Areia
Authors: Ribeiro Leandro Lima
Published: December 2022

Este estudo analisa, no quadro teórico-metodológico da semiótica  discursiva francesa, os contornos de uma retórica conservadora e intolerante  que esconde, por trás de sua configuração, violação de Direitos Humanos de  crianças e de adolescentes em situação de rua em Capitães da Areia (1937),  livro de Jorge Amado. Nesse sentido, mostra-se que, do ponto de vista da  organização narrativa, a exclusão como sanção pragmática está assentada na  lógica de dupla estigmatização social dos sujeitos marginalizados: a invisibilidade  e a (ultra)visibilidade. Para além disso, o romance esboça a atuação do Estado  Penal e a sua metodologia de punição e exclusão dos mais pobres. Em síntese,  evidencia-se uma descontinuidade com o projeto de identidade nacional  fundamentado na eufórica celebração da mistura e na noção de democracia  racial e cordial.
As culturas binárias e ternárias: da intolerância à tradução semiótica
Authors: Nakagawa Regiane Miranda de Oliveira , Nakagawa Fábio Sadao
Published: December 2022

Com base na formulação proposta pelo semioticista da cultura Iuri  Lotman, interessa-nos discutir de que maneira as estruturas binárias elucidam  o funcionamento semiótico da intolerância, diferentemente do que ocorre com  as estruturas ternárias, que se caracterizam pela ambivalência e pelo  intercâmbio com diferentes esferas culturais. Ambas serão exploradas como  tipologias que, segundo Lotman, prevê a apreensão das culturas como sistemas  de linguagens que se organizam com base na presença de um dominante. Assim,  no caso das estruturas binárias, isso ocorre por meio da dinâmica espacial  estabelecida entre interior/ exterior ou dentro/ fora, da qual decorre a  separação entre a “cultura própria” e o “alheio”, de modo que tudo o que não faz  parte da primeira é visto como uma ameaça, gerando a intolerância. Por outro  lado, nas estruturas ternárias, o “diferente” é considerado fonte de informação  pela qual se constroem individualidades caracterizadas pela diversidade e pela  heterogeneidade semiótica. Com essa discussão, objetivamos indicar de que  maneira se dá a compreensão da intolerância como um fenômeno semiótico  cultural e como ela é constantemente tensionada pelo movimento do espaço  semiótico de relações.
Therapeutic options for hemarthrosis in severe hemophilic patients
Authors: Costa Franciely Vanessa , Cordeiro Maria Eduarda Coelho , Silva Renata Luiz da , Antunes Maria Cecília , Selau Bruna Gonçalves , Moran Cristiane Aparecida
Published: December 2022

the coagulation factors VIII (FVIII) or IX (FIX), respectively. The primary therapeutic approach is to replace the deficient coagulation factor, which can be achieved with factors derived from human plasma or recombinants. However, despite having a therapeutic approach, most severe cases are symptomatic and may have complications, mainly in the muscles and joints. One example of such disorder is hemarthrosis. This manifestation tends to affect mainly the knee, ankle, or elbow joints in about 80% of cases. Objective: to describe the primary forms of treatment for joint bleeding in patients with severe hemophilia. Methods: This is a qualitative research of the integrative review type meant to identify productions on topics associated with hemarthrosis and severe hemophilia. The articles were searched through the databases PubMed, Scientific Electronic Library Online (Scielo) and Virtual Health Library (BVS) with the following search descriptors: “hemarthrosis andhemophilia”; “joint diseases and Hemophilia” and corresponding terms in Portuguese. The inclusion criteria were as follows:a) scientific articles b) available in full-text c) studies available in Portuguese, English, or Spanish d) randomized clinical trials e) articles published between 2016 and 2021 f) articles containing hemarthrosis caused by severe hemophilia. As exclusion criteria, texts that had no relation to the theme, did not answer the guiding question, other types of articles that did not include randomized clinical trials and/or presented duplicates were discarded. Results: In total, 42 articles were found in the selected databases; eight were duplicated, and 25 were excluded for not being randomized clinical trials or because they did not contemplate the theme. After careful reading, nine articles that met the inclusion and exclusion criteria were identified. Of the eligible studies, one reported factor replacement, and eight reported physiotherapeutic treatment. Conclusion: Factor replacement for hemophilic patients is essential and, based on the information obtained, early replacement is beneficial for the patient to avoid joint complications. Prophylaxis is indicated in severe hemophilia and its main objective is to prevent recurrent hemarthrosis, which can cause permanent functional deformities. Some physiotherapeutic interventions are indicated to prevent joint damage in severe hemophilic patients. The findings show diversity in the physical therapy modalities employed. The complete prevention of joint damage is still a challenge. A combination of treatments and a multidisciplinary team follow-up is necessary to ensure health and quality of life of patients.
Progression of Relapsing-Remitting Multiple Sclerosis despite the new era of treatments
Authors: Santos Gutemberg Augusto Cruz dos , Salles Gabriel Etienne Brito de , Silva Milenna Grisoli Martins  da , Cabral Roxanne Cabral
Published: December 2022

Objective. The present study aims to evaluate the conditions associated with the progression of Multiple Sclerosis (MS) and patients' dysfunctions. Methods. We perform a retrospective longitudinal analytical observational study in 46 patients with MS from a polyclinic at Rio de Janeiro, Brazil. We used the Expanded Disability Status Scale (EDSS) to rank the patients according to their disability and establish correlation with risk factors, treatment and time of disease. Results. Of 46 patients, 69.6% were female and 67.4% were white. Patients with fewer functional systems affected at the beginning of the disease had a longer time for disease progression, according to EDSS. Low efficacy drugs led to a high rate of discontinuation of the treatment. Patients who used a continuously treatment took longer to reach higher EDSS values ​​than those who discontinued treatment. Conclusion. Despite the control of MS with high effective drugs, there is still some disability for the patient. The factors that influenced the progression of the disability were: multiple symptoms at the beginning of the disease, more than 30 years old at the beginning of the MS, delay in diagnosis and initiation of treatment, among others.
Caracterização da produção brasileira em terapia ocupacional e contextos hospitalares de 2006 e 2019: um estudo de dois periódicos nacionais
Authors: Ferreira Gabriel Paiva , Arthur Mariana Aparecida , Galheigo Sandra Maria
Published: December 2022

A caracterização da produção científica no campo do cuidado em saúde pode contribuir para a obtenção de indicadores de seu crescimento e consolidação. O objetivo do estudo foi caracterizar a produção científica de terapia ocupacional e contextos hospitalares. Foi realizada revisão de escopo das publicações nos Cadernos Brasileiros de Terapia Ocupacional e na Revista de Terapia Ocupacional da USP entre 2006 e 2019, com a leitura do título, resumo e palavras-chave e, quando necessário, leitura do texto. A seleção utilizou alguns critérios de inclusão. Após o preenchimento do banco de dados foram produzidos relatórios, posteriormente analisados. Foram identificados 126 artigos, sendo 103 artigos originais, 16 relatos de experiência e 7 revisões de literatura. Há clara tendência de crescimento da produção, com significativa influência acadêmica, predominância do sudeste, baixa cooperação internacional e recebendo pouco recurso de agências de fomento. Os artigos constituem a maioria das produções, com significativa presença de pesquisa qualitativas. Os artigos e os relatos de experiência se dirigem principalmente à população adulta e idosa, mudando a tendência encontrada em estudo anterior. Para a consolidação e qualificação da pesquisa e prática em terapia ocupacional e contextos hospitalares é fundamental a realização de estudos de caracterização com desenhos distintos.
Núcleo Poiesis: uma construção interinstitucional para o fortalecimento dos estudos e práticas sobre terapia ocupacional e trabalho
Authors: Souza Marina Batista Chaves Azevedo de , Barroso Bárbara Iansã de Lima , Alonso Carolina Maria do Carmo , Nogueira Lilian de Fatima Zanoni , Oliveira Priscilla Viégas Barreto de , Silva Talita Naiara Rossi da , Rodrigues Daniela da Silva
Published: December 2022

O Núcleo Poiesis - Laboratório Interinstitucional de Terapia Ocupacional e Trabalho, nasceu da vontade de estabelecer ações coletivas, parcerias interinstitucionais e experimentações acadêmicas entre docentes e terapeutas ocupacionais que estudam o trabalho. Esse relato de experiência descreve o processo de construção do Núcleo Poiesis, apresenta o perfil de suas pesquisadoras, suas produções e parcerias, seus projetos futuros e as contribuições desse grupo para os estudos e práticas sobre terapia ocupacional e trabalho. Enquanto coletivo, as produções somaram até então dois artigos, quatro capítulos de livros, além de parcerias interinstitucionais em ensino, pesquisa e extensão, coordenação de debates sobre terapia ocupacional e trabalho nos principais congressos, eventos e instituições representativas da profissão no país. Conclui-se que a experiência coletiva de pares promoveu uma interlocução entre as universidades espalhadas por todo território nacional, o que é indispensável para promover trocas de experiências, saberes e práticas no campo do trabalho e Terapia Ocupacional.
Panorama teórico-prático da terapia ocupacional na atenção à saúde cardiovascular ao adulto e ao idoso: uma revisão integrativa
Authors: Freitas Lucidalva Costa de , Almeida Maria Helena Morgani de , Toldrá Rosé Colom , Kojima Helga Juri , Batista Marina Picazzio Perez
Published: December 2022

Introdução: As evidências científicas acerca das especificidades da atuação do terapeuta ocupacional nas doenças cardiovasculares são insuficientes. Objetivos: Conhecer o panorama teórico-prático da terapia ocupacional na atenção à saúde cardiovascular ao adulto e ao idoso. Método: Revisão bibliográfica integrativa da literatura indexada nas bases de dados PSYcInfo; Cochrane; Web of Science; PUBMED; SCOPUS; EMBASE; LILACS; SciELO; CINAHL; Rehabilitation & Sports Medicine Source; Academic Searcher Premier, com recorte temporal de 1917 a 2020. Resultados: Identificou-se que diferentes aspectos são abordados nas intervenções, tais como: educação em saúde, conservação de energia, aumento da autopercepção da saúde, otimização da capacidade funcional residual e retorno ao máximo possível da condição anterior ao evento cardíaco, engajamento em atividades significativas, apoio emocional e estímulo à mobilidade, ao gerenciamento do estresse, à participação comunitária. Conclusão: Identificou-se atuação da Terapia Ocupacional na atenção à saúde cardiovascular, em especial no contexto hospitalar em equipes de reabilitação cardíaca, o que mostra a necessidade de outros estudos que evidenciem sua relevância em contextos territoriais.
Construção de um modelo teórico representativo da experiência: terapeutas ocupacionais significando o brincar nos Centros de Atenção Psicossocial Infantojuvenis
Authors: Rodrigues Natani Alves , Mieto Fernanda Stella Risseto
Published: December 2022

A pesquisa teve como objetivo construir um modelo teórico representativo da experiência dos terapeutas ocupacionais trabalhadores dos Centros de Atenção Psicossocial Infantojuvenis (CAPSij) que identifique os significados dados ao brincar na sua prática profissional. O estudo de abordagem qualitativa utilizou como referencial metodológico a Teoria Fundamentada nos Dados. Participaram da pesquisa oito terapeutas ocupacionais de CAPSij do município de São Paulo. A análise comparativa dos dados possibilitou identificar dois fenômenos que compõem a experiência: “Tendo um saber da terapia ocupacional sobre o brincar” e “Identificando forças contrárias à sustentação do brincar”. A articulação desses fenômenos permitiu identificar a categoria central “O terapeuta ocupacional sustentando o lúdico na sua prática clínica no CAPSij”, a partir do qual se propõe um modelo teórico. Os resultados do estudo foram interpretados à luz da perspectiva winnicottiana na construção do cuidado em terapia ocupacional que concebe o brincar como elemento constitutivo da experiência de ser criança. O modelo teórico construído apresenta que o terapeuta ocupacional possui consistente conhecimento teórico e formação ético-política para produzir estratégias de sustentação do lúdico no CAPSij diante de forças hegemônicas contrárias.
As práticas de terapia ocupacional no primeiro ano da pandemia de COVID-19 – revisão bibliográfica
Authors: Arthur Mariana Aparecida , Santos Vitória Silvia , Oliver Fátima Corrêa , Souto Ana Cristina Fagundes
Published: December 2022

Em 2020 a COVID-19 chega ao Brasil e logo se confirma transmissão comunitária. São realizados debates que, em meio à falta de coordenação nacional, produzem respostas diferentes em cada nível de governo. Há ênfase na atenção hospitalar, necessária para o atendimento dos casos graves. As mudanças na assistência refletem-se em todos os níveis de atenção em Saúde, Educação e Assistência Social em que terapeutas ocupacionais atuam. Objetivou-se conhecer e agrupar as comunicações cientificas de terapeutas ocupacionais no primeiro ano da pandemia. Em março de 2021 realizou-se uma revisão bibliográfica na Biblioteca Virtual de Saúde que inclui a base Scientific Eletronic Library Online, Portal de Periódicos da Coordenadoria de Aperfeiçoamento de Pessoal de Nível Superior, além do rastreio nas páginas eletrônicas de sete periódicos ibero-americanos de Terapia Ocupacional. Foram utilizados os descritores “occupational therapy” combinado com os descritores “COVID-19”, “coronavirus”, “pandemics”, “quarantine”, “syndemics”. Foram incluídos títulos com práticas implementadas durante a pandemia, escritos por ao menos um terapeuta ocupacional, cujo texto estava integralmente disponível, perfazendo 17 artigos agrupados por campo, nível de atenção, população. Predomina a atenção hospitalar com práticas adaptadas à biossegurança, seguida da Atenção Básica, e ampla adoção da Telessaúde.
Multiomic Spatial Mapping of Myocardial Infarction and Implications for Personalized Therapy
Authors: Schumacher David , Kramann Rafael
Published: December 2022

Ischemic heart disease including myocardial infarction is still the leading cause of death worldwide. Although the survival early after myocardial infarction has been significantly improved by the introduction of percutaneous coronary intervention, long-term morbidity and mortality remain high. The elevated long-term mortality is mainly driven by cardiac remodeling processes triggering ischemic heart failure and electric instability. Despite the new developments in pharmaco-therapy of heart failure, we still lack targeted therapies for cardiac remodeling and fibrosis. Single-cell and genomic technologies allow us to map the human heart at unprecedented resolution and allow to gain insights into cellular and molecular heterogeneity. However, these technologies rely on digested tissue and isolated cells or nuclei and thus lack spatial information. Spatial information is critical to understand tissue homeostasis and disease and can be utilized to identify disease-driving cell populations and mechanisms including cellular cross-talk. Here, we discuss recent advances in single-cell and spatial genomic technologies that give insights into cellular and molecular mechanisms of cardiac remodeling after injury and can be utilized to identify novel therapeutic targets and pave the way toward new therapies in heart failure.
Ambient Air Pollution and Stroke: An Updated Review
Authors: Kulick Erin R. , Kaufman Joel D. , Sack Coralynn
Published: December 2022

Despite recent advances in treatment and prevention, stroke remains a leading cause of morbidity and mortality. There is a critical need to identify novel modifiable risk factors for disease, including environmental agents. A body of evidence has accumulated suggesting that elevated levels of ambient air pollutants may not only trigger cerebrovascular events in susceptible people (short-term exposures) but also increase the risk of future events (long-term average exposures). This review assesses the updated evidence for both short and long-term exposure to ambient air pollution as a risk factor for stroke incidence and outcomes. It discusses the potential pathophysiologic mechanisms and makes recommendations to mitigate exposure on a personal and community level. The evidence indicates that reduction in air pollutant concentrations represent a significant population-level opportunity to reduce risk of cerebrovascular disease.
In Pursuit of a Multimodal Ensemble in a Stop-motion Animation Movie Created by Six Young Children
Authors: Undheim Marianne , Hoel Trude
Published: December 2022

In this article, the authors explore the visual and auditive modes in a stop-motion animation movie created by six young children in collaboration with their teacher. Drawing on social semiotic multimodal perspectives as the theoretical framework, the authors apply the concepts of multimodal orchestration and multimodal ensemble to discuss the relationship between the modes. This study is a qualitative case study in which the movie and video recordings from the production are used as data. The findings indicate that the relationship between the modes is characterized by layers that partially interact; sometimes they do and sometimes they do not. The moving images form the basis, while the voiceovers and background music to a small extent deepen or nuance the visual mode. In the article the authors question whether the sequential design of the digital apps used in the production of the movie may have contributed to this partial interaction between the modes.
Qualitative Analysis of the Lived Experience of Tornado Survivors and Factors Affecting Community Resilience: A Case Study of an EF3 Tornado in Jacksonville, Alabama
Authors: Wang Chongming , Rider Erin , Manning Scott , Fast Jacob , Islam Tanveer
Published: December 2022

Residents in the Southeast region of the United States are frequently threatened by tornadoes. Previous research indicates that it is important to study the experience of tornado victims to better understand individual risk perception, preparedness, protective action, response, and recovery strategies that contribute to overall community resilience. In this study, we employ an oral-history approach and analyze the lived experience of survivors of an EF3 (on the enhanced Fujita scale) tornado in Jacksonville, Alabama. Using snowball sampling, we conducted in-depth interviews of 25 residents of Jacksonville, Alabama, who experienced the EF3 tornado on 19 March 2018. The recorded interviews were analyzed using qualitative software. Most of the participants described the support system and the range of resources accessible through the network of relations as the critical factors that facilitated recovery and contributed to resilience. The majority also emphasized the importance of being prepared and proactive when addressing future storms, but some of their actions revealed that they were also used to being reactive. The participants were either long-term residents (homeowners) or transient college students (renters), and the data gave insight into different recovery paths and challenges. Further, findings revealed ongoing trauma and recovery challenges due to the extensive, unexpected damage and the lack of temporary housing and contractor availability often associated with small, rural towns. This research aims to provide a scientific basis for improved efforts in preparedness and protective actions as well as in response and recovery strategies in tornado events and for identifying factors of community resilience in tornado-prone areas.

Significance Statement

Grounded in the narratives and reflections of the participants on their tornado experiences, the oral-history interviews generated important insights into psychological–behavioral responses to a disaster, as well as key building blocks of resilience, adding to the body of research surrounding disaster impact and vulnerability, especially for small, rural towns. The preserved voices, stories, and social memory are expected to benefit current and future generations of the community facing similar threats. The findings of this study will further help to inform better practice of local emergency managers and government officials for promoting public awareness of tornadoes and other weather-related risks so as to be more prepared for future extreme weather events.
Associations of suicide-related media reporting characteristics with help-seeking and suicide in Oregon and Washington
Authors: Niederkrotenthaler Thomas , Laido Zrinka , Gould Madelyn , Lake Alison M , Sinyor Mark , Kirchner Stefanie , Braun Marlies , Chowdhury Saba , Gonzalez Frances , Draper John , Murphy Sean , Till Benedikt
Published: December 2022

Objective:

Specific content characteristics of suicide media reporting might differentially impact suicides in the population, but studies have not considered the overarching theme of the respective media stories and other relevant outcomes besides suicide, such as help-seeking behaviours.

Methods:

We obtained 5652 media reports related to suicide from 6 print, 44 broadcast and 251 online sources in Oregon and Washington states, published between April 2019 and March 2020. We conducted a content analysis of stories regarding their overarching focus and specific content characteristics based on media recommendations for suicide reporting. We applied logistic regression analyses to assess how focus and content characteristics were associated with subsequent calls to the US National Suicide Prevention Lifeline (Lifeline) and suicides in these two states in the week after publication compared to a control time period.

Results:

Compared to a focus on suicide death, a focus on suicidal ideation, suicide prevention, healing stories, community suicide crises/suicide clusters and homicide suicide was associated with more calls. As compared to a focus on suicide death, stories on suicide prevention and stories on community suicide crises/suicide clusters were also associated with no increase in suicides. Regarding specific content characteristics, there were associations that were largely consistent with previous work in the area, for example, an association of celebrity suicide reporting with increases in suicide.

Conclusion:

The overall focus of a media story may influence help-seeking and suicides, and several story characteristics appear to be related to both outcomes. More research is needed to investigate possible causal effects and pathways.