bluuebunny/crossref_metadata_2025 huggingface dataset:
Educational Dental Keychains Application in Student Team Achievement Division : Implementation of Dental and Oral Health Promotion
Authors: Wardani Ika Kusuma , Putri Deby Kania Tri , Dewi Nurul Fitriyani , Kirana Fatma , Rahimah Aulia , Maulideya Fatimah , Nisa Jamilatun
Published: October 2023

ABSTRACT The implications of effective, efficient, attractive dental and oral health promotion are closely related to a person's level of awareness and behavior in improving the maintenance of oral health and hygiene. The purpose of this community service is to implement the use of Educational Dental Keychains in Student Team Achievement Division as an effort to promote oral health.  The method used 6 steps, they are consisting of conveying goals and motivating students, convey goals and information, motivating students, organizing and guiding students in study groups, evaluating learning outcomes, clarification and feedback by experts and giving awards.: The application of Educational Dental Keychains in the Student Team Achievement Division as an effort to promote dental and oral health has a good influence on students' dental and oral knowledge and a good understanding of students' dental and oral health knowledge. Student knowledge increased descriptively and statistically. The use of Educational Dental Keychains and the STAD health promotion method can be applied as an effort to increase oral and dental health knowledge in children. Keyword: Educational Dental Keychains, health promotion, Student Team Achievement Division, Dental and Oral Health Knowledge, Children
Edukasi dan Pemanfaatan Labu Kuning sebagai Bahan Pangan Sehat di Desa Wisata Jamalsari
Authors: Ramonah Dewi , Puspitasari Dewi Fitriani , Pratiwi Arik Dian Eka , Wulandari Wulandari
Published: October 2023

ABSTRAK Desa Wisata Jamalsari, Kelurahan Kedungpane, Kecamatan Mijen, Semarang, Jawa Tengah memiliki julukan “Kampung Tematik Labu” karena cukup banyak tanaman labu kuning yang dibudidayakan. Labu kuning (Cucurbita moschata Duchesne) merupakan salah satu tanaman yang dapat dimanfaatkan sebagai bahan dasar olahan makanan, salah satunya adalah kue bolu. Pemanfaatan hasil bumi ini belum optimal. Pengabdian ini bertujuan untuk memberikan edukasi pangan sehat dan pelatihan terkait pembuatan produk pangan sehat berupa kue bolu yang berbahan dasar labu kuning, diharapkan dengan  kegiatan tersebut dapat meningkatkan pula pemberdayaan ibu-ibu dan remaja perempuan. Metode pengabdian yang dilakukan dengan memberikan edukasi warga terkait pangan sehat dan olahan labu kuning melalui pemaparan materi dan pelatihan pembuatan bolu labu kuning kepada warga. Kesimpulan dari kegiatan pengabdian ini warga menjadi teredukasi terkait sumber pangan sehat labu kuning serta warga dapat membuat produk serupa. Melaui edukasi dan pelatihan, dapat meningkatkan pemberdayaan warga. Kata Kunci: Labu Kuning, Kue Bolu, Jamalsari  ABSTRACT Jamalsari Tourism Village, Kedungpane Village, Mijen Subdistrict, Semarang, Central Java, has the nickname "Pumpkin Thematic Village" because of the large number of pumpkin plants that are cultivated. Pumpkin (Cucurbita moschata Duchesne) is one of the plants that can be utilized as a basic ingredient for processed foods, one of which is sponge cake. The utilization of this crop has not been optimal. This service aims to provide healthy food education and training related to making healthy food products in the form of sponge cake made from pumpkin, it is hoped that these activities can also increase the empowerment of mothers and young women. The service method is carried out by educating residents regarding healthy food and processed pumpkin through material presentation and training in making pumpkin sponge cake to residents. The conclusion of this service activity is that residents become educated regarding healthy food sources of pumpkin and residents can make similar products. Through education and training, it can increase community empowerment. Keywords: Yellow Pumpkin, Sponge Cake, Jamalsari
Deteksi Dini Faktor Risiko Penyakit Tidak Menular Pada Masyarakat di Negeri Hatumete Kecamatan Tehoru Kabupaten Maluku Tengah
Authors: Natsir Ramdhani M
Published: October 2023

ABSTRAK Deteksi dini faktor risiko penyakit menular adalah suatu tindakan proses mengidentifikasi faktor-faktor yang dapat meningkatkan risiko seseorang untuk terkena penyakit tidak menular (PTM). Penyakit tidak menular adalah penyakit yang tidak disebabkan oleh infeksi dan tidak dapat ditularkan dari orang ke orang lainnya. Beberapa contoh penyakit tidak menular termasuk penyakit diabestes, kolesterol dan dan asam urat. Tujuan kegiatan pengabdian ini adalah menumbuhkan kesadaran dan pengetahuan masyarakat dalam pemantauan faktor risiko melalui pemanfaatan pemeriksaan penyakit tidak menular (PTM). Kegiatan ini dilaksanakan dalam dalam bentuk penyuluhan dan pemeriksaan kesehatan. Dari hasil pre test dan post test yang dilakukan saat penyuluhan, dapat diketahui bahwa terjadi peningkatan pengetahuan di ketiga aspek yang diukur setelah dilakukan penyuluhan. Terjadi rata-rata peningkatan pengetahuan setelah dilakukan kegiatan masyarakat sebanyak 96 % dari jumlah total kuesioner. Dari hasil pemeriksaan kesehatan yang dilakukan, didapatkan bahwa pada perempuan memiliki hasil pemeriksaan yang tidak normal lebih banyak daripada laki-laki. Hal   ini   menunjukkan bahwa perempuan sangat beresiko terkena penyakit tidak menular. Kata Kunci: Faktor Risiko, Penyakit Tidak Menular, Pemeriksaan  ABSTRACT Early detection of infectious disease risk factors is a process of identifying factors that can increase a person's risk of contracting a non-communicable disease (NCD). Non-communicable diseases are diseases that are not caused by infection and cannot be transmitted from person to person. Some examples of non-communicable diseases include diabetes, cholesterol and gout. The aim of this service activity is to increase public awareness and knowledge in monitoring risk factors through the use of non-communicable disease (PTM) examinations. This activity is carried out in the form of counseling and health checks. From the results of the pre-test and post-test carried out during the counseling, it can be seen that there was an increase in knowledge in the three aspects measured after the counseling was carried out. There was an average increase in knowledge after community activities as much as 96% of the total number of questionnaires. From the results of the health examinations carried out, it was found that more women had abnormal examination results than men. This shows that women are very at risk of contracting non-communicable diseases. Keywords: Risk factors, Non-Communicable Diseases, Examination
Bamboo Rafting: Upaya Meningkatkan Kesadaran Masyarakat di Desa Pengaron Tentang Mitigasi Bencana Banjir
Authors: Ariadi Herman , Maryam Maryam , Sari Nessa Anggun Permata , Rahmah Annisa , Fikri Muhammad , Raudah Sari Pandan
Published: October 2023

ABSTRAK Banjir sering terjadi karena meluapnya air sungai Martapura dan Riam Kiwa pada saat musim hujan. Faktor yang mempengaruhi banjir adalah curah hujan atau debit air yang tinggi yang menyebabkan volume air di aliran sungai Martapura dan Riam Kiwa bertambah dan air meluap menggenangi rumah warga. Tujuan kegiatan setelah pelatihan mitigasi bencana banjir dan pembuatan evakuasi Bamboo Rafting, diharapkan mampu memberikan pemahaman mitigasi bencana banjir dan mampu membuat evakuasi Bamboo Rafting. Adapun kegiatan yang dilakukan berupa pelatihan mitigasi bencana banjir dan menciptakan alat evakuasi banjir Bamboo Rafting. Terdapat peningkatan pengetahuan mitigasi bencana banjir dan keterampilan membuat Bamboo Rafting di Desa Pengaron. Dengan demikian pelatihan mitigasi bencana dan pembuatan evakuasi Bamboo Rafting sangat efektif dalam meningkatkan pengetahuan dan keahlian membuat Bamboo Rafting. Kata Kunci: Mitigasi Bencana, Banjir, Bamboo Rafting  ABSTRACT Floods often occur due to the overflow of the Martapura and Riam Kiwa rivers during the rainy season. Factors that influence flooding are rainfall or high water discharge which causes the volume of water in the Martapura and Riam Kiwa rivers to increase and the water to overflow inundates residents' houses. The aim of the activity after training on flood disaster mitigation and making Bamboo Rafting evacuations is to be able to provide an understanding of flood disaster mitigation and be able to make Bamboo Rafting evacuations. The activities carried out included flood disaster mitigation training and creating the Bamboo Rafting flood evacuation tool. There is an increase in knowledge of flood disaster mitigation and skills in making Bamboo Rafting in Pengaron Village. Thus, disaster mitigation training and making Bamboo Rafting evacuations are very effective in increasing knowledge and skills in making Bamboo Rafting. Keywords : Disaster Mitigation, Flood, Bamboo Rafting
ЗОВНІШНЯ РОЗВІДКА ЯК НАПРЯМ ОПЕРАТИВНОЇ ДІЯЛЬНОСТІ ОРГАНІВ ДЕРЖАВНОЇ БЕЗПЕКИ УКРАЇНИ В УМОВАХ ГЛОБАЛЬНОГО ВОЄННО-ПОЛІТИЧНОГО ПРОТИСТОЯННЯ У СВІТІ (1954–1991 рр.)
Authors: Вєдєнєєв Дмитро
Published: October 2023

У статті на основі документальної спадщини спецслужб та дослідницьких праць розкривається місія та основні напрями оперативної діяльності підрозділу зовнішньої розвідки (1-го Управління) Комітету державної безпеки Української РСР в період “холодної війни”. Розкривається еволюція організаційно-функціональної побудови розвідки. Досліджується організація та основні результати роботи за напрямками політичної, науково-технічної, гуманітарної розвідки, розробки закордонних осередків української політичної еміграції та конфесійних об’єднань. Окремо висвітлюються деякі довготривалі спеціальні операції  та досвід оперативно-бойової діяльності під час Афганської війни 1979–1989 рр.
Evaluation of Renal Function Following Percutaneous Nephrolithotomy in Patients with Previously Operated Renal Calculi
Authors: Joarder Md Abdul Baten , Islam Md Faisal , Chowdhury Anup Roy , Rajib Md Asaduzzaman , Rahman Mohammad Habibur , Babul Md Safiul Alam
Published: October 2023

Objective: Percutaneous nephrolithotomy (PCNL) is a safe and effective treatment modality for patients with renal stones, regardless of the history of previous surgery. For patients who have been previously treated for renal stones, half of them will face stone recurrence within 5-7 years. The objective is to evaluate the renal functional status following percutaneous nephrolithotomy in patients with previously operated renal calculi.
Materials and Methods: From July 2018 to June 2020, previously operated total 44 selected recurrent renal calculi patients underwent standard PCNL. Serum creatinine and renal 99mTc-DTPA scan were done pre-surgery and at post-operative 3 month and year 01, respectively. An assessment was done on renal function, comparing pre and post-operative values. Institutional ethical committee clearance was taken before the commencement of the study.
Results: Among 44 patients, 29 patients (65.9%) had a previous history of open stone surgery, and 15 patients (34.09%) underwent PCNL previously. Mean pre and postoperative serum creatinine were not significant between the cohorts (p=0.28). Mean pre-operative split renal functions (in 99mTc-DTPA) of patients (45.13±14.14%) were found almost stable in comparison to mean post-operative value (44.38±10.96%) and (46.99±9.66%) in 03 and 12-month follow-up respectively. Mean GFR for pre-operative and post-operative values were 42.23±6.03 mL/min, 45.93±5.47 mL/min, and 48.99±5.87 mL/min, respectively, which were not statistically significant. Based on serum creatinine and DTPA nuclear renogram, patients showed stability or improvement in renal function at post-operative follow-up. Summarily, a normal pre-operative serum creatinine, regardless of history of previous surgery, maintained stability rather than deterioration in renal function.
Conclusions: PCNL is an effective treatment modality in patients with previously operated renal calculi as parameters of renal function had remained stable or slightly improved in the majority of patients on post-operative follow-up.
Bangladesh J. Urol. 2022; 25(1): 28-32
Sequencing the Treatment of High-Risk Prostate Cancer: A Way Towards Multimodal Tailored Approaches: A changing Landscape
Authors: Salam Md Abdus
Published: October 2023

Abstract not available
Bangladesh J. Urol. 2022; 25(1): 45-61
Anatomo-topographic changes in the chewing device total loss of teeth in old people
Authors:   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Bohatyriova D.
Published: October 2023

Summary. This article highlights the problem of dental prosthetics for people of gerontological age with complete loss of teeth. In the study group, significant involutive processes of the facial skull were determined, especially the upper jaw, lower jaw, TMJ. These changes affect the stabilization of complete removable dentures, which are necessary to restore the functions of the oral cavity. This category of people requires considerable attention and qualified treatment, since it has a number of difficulties that do not allow full provision of dental care. Key words: TMJ, upper jaw, lower jaw, chewing muscles, complete removable dentures.
Experience of providing dental care in the conditions of the military state
Authors:   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Kanyura O. , Bidenko N. ,   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Kolenko Yu. ,   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Filonenko V. ,   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Khrol N. ,   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Shpak D. ,   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine
Published: October 2023

Relevance. The state of war had a significant impact on the provision of medical care to the population of Ukraine. Considering that dental care is one of its highly specialized types, the events in the country were fully reflected in it as well. The aim of the study. Summarize and analyze the experience of outpatient dental reception of patients in the conditions of the Dental Medical Center, which is a structural unit of the University Clinic of Bogomolets National Medical University, during the martial law period. Materials and methods. A retrospective analysis of 4,308 medical histories of persons who sought dental care at the Dental Medical Center of Bogomolets National Medical University within two months from the moment martial law was declared in Ukraine (February 28, 2022–April 30, 2022). The results. The work of the Dental Medical Center of Bogomolets National Medical University was restored practically from the first days of the declaration of martial law in Ukraine. For the period from 28.02 to of 30.04.2022 4,308 patients were admitted by the staff of the Dental Medical Center, of which 1,713 (39.8 %) were servicemen of the Armed Forces of Ukraine and soldiers of the Territorial Defense. Conclusions. The experience of organizing and conducting an outpatient dental appointment in the conditions of martial law, on the one hand, highlighted the problems of dental care for soldiers and conscripts before the start of a full-scale invasion, and on the other hand, it allowed to develop recommendations regarding the algorithm of the operation of a medical institution in extreme conditions. Key words: martial law, Dental Medical Center, emergency care, servicemen of the Armed Forces of Ukraine and soldiers of the Territorial Defense.
Comparative characteristics of the quality of prosthetics of the edentulous lower jaw with removable dentures based on the bol-abutments and on a beam system
Authors:   Azerbaijan Medical University, Baku, Azerbaijan, Safarov Mahir Alisa
Published: October 2023

Resume. The article presents the results of a long-term examination of prosthetics in 100 patients aged 55 to 73 years with a complete absence of teeth in the lower jaw, of which 62 were made removable dentures based on intraosseous implants with installed bol-abutments, and 38 patients were made removable dentures with based on intraosseous implants with an installed beam structure. A significant superiority of prosthetics based on a beam structure, was revealed in terms of quality of life, fixation of prostheses, as well as functional efficiency. At the same time, when using implants with installed large abutments, a large degree of atrophy of the alveolar part in the distal parts of the mandible was registered. The results obtained indicate the need for further research, in particular, by studying stress-strain states, in order to develop an algorithm for determining indications for various types of prosthetics in patients with a complete absence of teeth in the lower jaw. Key words: complete edentulous mandible, bol-abutment, bar constructionthe level of quality of life, the effectiveness of treatment.
Modern view of the classification, diagnostic and clinical manifestations of periodontitis in children and adolescents
Authors:   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Khomenko L. , Ostapko O. ,   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Bidenko N. ,   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine, Holubieva I. ,   National Medical University named after A.A. Bogomoltsa, Kyiv, Ukraine
Published: October 2023

Summary. In the article the modern international classification of periodontal diseases is considered. The expediency of it use in the practice of pediatric therapeutic dentistry is justified. Emphasized that every child needs early diagnostic of periodontal tissue status by periodontal probing and detection of bleeding during probing as the main clinical symptom of pathological process. The clinical and rentgenological manifestations of different forms of periodontitis, include associated with somatic diseases, are presented. Key words: children, periodontitis, classification, diagnosis
Results of dental examination of children with obstructive sleep apnea syndrome
Authors:   National University of Health Care of Ukraine named after P.L. Shupyka, Kyiv, Ukraine, Drogomyretska M. , Gergel I. ,   National University of Health Care of Ukraine named after P.L. Shupyka, Kyiv, Ukraine
Published: October 2023

Introduction. Obstructive apnea syndrome is a widespread pathology. According to researchers, more than 1 billion people worldwide suffer from this pathology, most of whom are undiagnosed and unaccounted for. One or another degree of OSAS with existing symptoms in 8-16% of adults. OSAS occurs 4 times more often in men and 7 times more often in obese people. Genetic susceptibility or a heavy family history of OSAS, as well as craniofacial anatomical abnormalities that lead to narrowing of the upper airways, may confer a higher risk of OSAS.he prevalence of OSAS in children is 1–5%, the peak incidence is determined between the ages of 2 and 6 (2.5 years for boys and 4 years for girls). The search for an effective solution to the relationship between the problem of obstructive sleep apnea and bite pathology is an extremely urgent and unsolved problem of modern dentistry and should be solved by a combination of complex rehabilitation of patients by specialists of various profiles. Goal. Assessment of the dental status of 233 patients aged 6–18 years with obstructive sleep apnea syndrome (OSAS). Research methods. Surveys, questionnaires using the BEARS screening questionnaire and a questionnaire to detect clinical signs of stomatognathic system disorders and bruxism in children, primary examination, clinical (including visualization with maximum opening of the mouth - Mallampati test); dental (determining occlusal contacts using a dental copier and photographing them for further analysis, and making BruxChecker dental thermoformed plates) and laboratory (studying diagnostic models in the articulator), statistical processing of the obtained results. The results. The TRH study of children with OSAS showed obstruction of the respiratory tract at different levels: nasopharynx, oropharynx, and larynx. Depending on the age group, the levels of obstruction differed significantly. In the 1st age group (6–12 years), narrowing of the respiratory tract at the level of the nasopharynx was found in 65.1%, at the level of the oropharynx – in 17.7%, at the level of the larynx – in 10.3% of children. The combination of airway narrowing at the level of the nasopharynx and larynx was determined in 6.9% of children. In adolescents aged 13–18 (II age group), airway obstruction at the level of the nasopharynx was determined in 10.3%, and combined at the level of the oropharynx and larynx – in 89.7%. Conclusions. The main principle in the diagnosis of OSA is the need to take a detailed history of life and disease, followed by a comprehensive physical examination, including an orthodontic examination to detect dental and jaw pathology, and treatment should be carried out through a multidisciplinary approach involving various specialists Key words: obstructive sleep apnea syndrome, bite pathology.
Non-trophic interactions amplify kelp harvest-induced biomass oscillations and biomass changes in a kelp forest ecological network model
Authors: Perälä T , Pesari SNK , Ahti PA , Lehtinen SO , Schoenrock KM , Kuparinen A
Published: October 2023

Kelp forests are important marine ecosystems providing habitat for numerous species. Despite over 50 yr of mechanical harvesting in the Northeast Atlantic, the indirect impacts of kelp harvesting and associated habitat loss on faunal species within kelp forests remain poorly understood. We investigated the consequences of kelp harvesting by developing an allometric trophic network model for a subtidal Northeast Atlantic kelp forest (dominated by Laminaria hyperborea). Additionally, we designed a novel mechanistic model to explore the non-trophic interactions between kelp and age-class 0 Atlantic cod Gadus morhua and between kelp and European lobster Homarus gammarus, specifically focusing on the increased survival benefits provided by the kelp habitat. Simulations were conducted over a 50 yr period, incorporating harvesting cycles of 2, 5, and 9 yr, as well as low and high harvesting intensities. Our findings reveal the complex dynamics resulting from kelp harvesting. The recovery of kelp biomass was observed with 5 and 9 yr harvesting cycles, whereas a decline was observed with a 2 yr cycle. Furthermore, the non-trophic interactions facilitated a higher pre-harvest biomass for both European lobster and Atlantic cod compared to scenarios without this interaction. These results highlight the multitrophic effects of kelp harvesting and emphasize that the recovery of kelp-associated species may not necessarily align with kelp recovery, depending on harvesting intensity and recovery periods. Importantly, our study contributes to a better understanding of the ecological consequences of kelp harvesting and underscores the need for sustainable management practices to mitigate habitat loss in kelp ecosystems.
Estuarine zooplankton communities shift but are not depleted during recurrent harmful algal blooms of Heterosigma akashiwo in the Sundays Estuary, South Africa
Authors: Bornman E , Adams JB , Strydom NA
Published: October 2023

Anthropogenically derived eutrophication and harmful algal blooms (HABs) are both a direct and indirect threat to estuarine ecosystems globally. Micro- and mesozooplankton play a crucial intermediary role in the functioning of estuarine systems. Therefore, the impacts of HABs on zooplankton communities and estuarine productivity are of interest worldwide. This study aimed to determine the changes in the zooplankton community structure in the anthropogenically altered Sundays Estuary, South Africa, which is affected by predictable and recurrent HABs of the raphidophyte Heterosigma akashiwo. Monthly sampling was conducted over 24 mo between 2018 and 2021. This was coupled with twice weekly sampling of 2 complete HAB cycles comprising no bloom, accumulation, and hypereutrophic bloom phases (during the austral spring in 2018). Generalised linear models found that salinity (31.3%) and temperature (12.1%) were positively related to zooplankton in Sundays Estuary. There was no major zooplankton mortality resulting from hypoxia or HABs during the sampling interval adopted for this study. The ubiquitous calanoid copepod Pseudodiaptomus hessei occurred at similar abundances among the HAB phases and responded to similar triggers (temperature and salinity) as the HAB species. However, predatory or scavenging invertebrates such as the isopod Cirolana fluviatilis and the polychaete Perinereis falsovariegata were recorded in higher abundances, suggesting a shift in the community structure due to HABs. The possible negative effects of the H. akashiwo HABs on the zooplankton species are likely dependent on their concentration and duration, which may fluctuate spatially and temporally in estuaries based on the river inflow and temperature.
K VIRTUALIZÁCII PRÁVNYCH PREDPISOV PROSTREDNÍCTVOM ESBÍRKY
Authors:   Masaryk University Brno, Krištofík Andrej
Published: October 2023

ON THE VIRTUALISATION OF LEGISLATION VIA THE ECOLLECTION Proces virtualizácie opisuje takú zmenu v predmetnom fenoméne, pri ktorej dochádza k odstraňovaniu, či inej zmene formálnych znakov, za súbežného zachovania podstaty tohto fenoménu. Pre tento proces poskytujú vhodné prostredie najmä informačno-komunikačné technológie, i keď nepredstavujú jeho definičný znak. S ich využitím je možné virtualizovať mnohé fenomény „aktuálneho“ sveta a s týmto oslobodením od formálnych znakov ho v nejakom smere zlepšiť. To je v určitej rovine i myšlienka navrhovanej elektronickej promulgácie práva v Českej republike, resp. navrhovaného projektu eSbírka, ktorá by mala práve vďaka odstránením formálnym znakom posilniť mnohé iné znaky tvoriace podstatu promulgácie a normotvorby, ako je aktuálny jazyk a prístupnosť a prehladnosť platného práva, či dokonca umožniť platnému právu „kyberneticky“ reagovať na zmeny regulovaného prostredia. URL: http://sic.pravo.upjs.sk/ The process of virtualization describes a change in the phenomenon in question in which the formal features are removed or otherwise altered, while preserving the essence of the phenomenon. Information and communication technologies, in particular, provide a suitable environment for this process, although they do not constitute its defining feature. Using them, it is possible to virtualise many phenomena of the 'actual' world and, with this freedom from their formal features, to improve upon them. This is, in a way, also the idea of the proposed electronic promulgation of law in the Czech Republic, or the proposed eCollection project, which should, precisely by removing formal features, strengthen many other features that constitute the essence of promulgation and law making, such as actual language and the accessibility and clarity of the applicable law, or even enable the applicable law to "cybernetically" respond to changes in the regulated environment.
VOJENSKÉ VYZVEDAČSTVO A TRIANON
Authors:   Pavol Jozef Šafárik University in Košice, Pandy Dávid
Published: October 2023

MILITARY ESPIONAGE AND TRIANON Predkladaný článok sa venuje výskumu činnosti zameranej na vyzvedanie a vyzrádzanie vojenských tajomstiev na území Československa v období po uzatvorení Trianonskej mierovej zmluvy. Autor túto činnosť zaraďuje medzi formy iredenty prameniacej z „okliešteného“ Maďarska sledujúcej zvrátenie výsledkov trianonského mieru. Príspevok analyzuje a porovnáva pôvodne uhorskú trestnoprávnu úpravu a výsledky normotvorby československého zákonodarcu sledujúcich potieranie týchto aktivít. Príspevok tiež popisuje čiastkové výsledky archívneho výskumu vo vzťahu k rozhodovacej činnosti súdu v trestných veciach tejto povahy. URL: http://sic.pravo.upjs.sk/ The presented article is dedicated to the research of the activities aimed at the collection and disclosure of military secrets on the territory of Czechoslovakia in the period after the conclusion of the Trianon Peace Treaty. The author classifies this activity among the forms of irredentism stemming from "truncated" Hungary aiming the reversal of the results of the Trianon Peace. The paper analyzes and compares the originally Hungarian criminal legislation and the results of the Czechoslovak legislator's activity aiming the suppression of these activities. The paper also describes the partial results of archival research in relation to the judicial practice in criminal matters of this nature.
UPRÁZDNENÉ MIESTO VEDÚCEHO (RIADITEĽA) ROZPOČTOVEJ ALEBO PRÍSPEVKOVEJ ORGANIZÁCIE OBCE A MOŽNOSTI JEHO OBSADZOVANIA
Authors:   Pavol Jozef Šafárik University in Košice, Žuľová Jana , Švec Marek ,   Univerzita Mateja Bela v Banskej Bystrici
Published: October 2023

VACANT POSITION OF HEAD (DIRECTOR) OF THE BUDGETARY OR CONTRIBUTORY ORGANIZATION OF THE MUNICIPALITY AND POSSIBILITIES OF ITS FILLING Predkladaný príspevok sa zaoberá analýzou právnej úpravy obsadzovania miesta vedúceho (riaditeľa) rozpočtovej alebo príspevkovej organizácie zriadenej obcou. Vo vnímaní a pri aplikácii tejto právnej úpravy možno identifikovať viacero sporných okruhov. Osobitne autori skúmajú hypotézu, či je možné tieto miesta dočasne obsadiť, t. j. či starosta obce (obdobne primátor mesta) môže dočasne poveriť výkonom funkcie osobu, ktorá neprešla schvaľovacím procesom podľa § 11 ods. 4 písm. l) zákona o obecnom zriadení. URL: http://sic.pravo.upjs.sk/ The submitted article deals with the analyse of the legal regulation of filling job of the head (director) of the budgetary or contributory organization established by the municipality. Several controversial areas can be identified in the perception and application of this legislation. In particular, authors examine the hypothesis, whether it is possible to temporarily filling these places, i.e. j. whether the mayor of the village (similarly the mayor of the city) can temporarily entrust the performance of function a person who has not passed the approval process according to § 11 par. 4 letters l) of the Municipal Establishment Act.
HOUSE PRICE PREDICTION USING MACHINE LEARNING
Authors: Kanade Vaishnavi , Thalor Dr. Minakshi ,   AISSMS IOIT
Published: October 2023

Machine Learning (ML) has profoundly impacted various domains, including speech recognition, healthcare, and automotive safety. Acknowledging its pervasive influence, our project aims to harness ML's capabilities for housing price prediction. In the volatile real estate market, prospective buyers strive to make informed decisions within budget constraints, often hindered by the absence of reliable future market trend forecasts. Our project's primary goal is to provide accurate house price predictions, mitigating potential financial losses. To achieve this, we are developing a housing cost prediction model employing ML algorithms such as Linear Regression, Decision Tree Regression, KMeans Regression, and Random Forest Regression. This model empowers individuals to invest in real estate without intermediaries. Our research highlights Random Forest Regression as the most accurate model, offering a promising avenue for confident real estate investment.
MSME: ISSUES AND CHALLENGES OF EMPOWERMENT OF WOMEN IN INDIA
Authors:   Swami Shukdevanand College,, Tiwari Dr. Vijai
Published: October 2023

: The present study investigates the correlation between women's empowerment and Micro, Small, and Medium Enterprises (MSMEs) within the Indian environment. It seeks to clarify the ways in which women's economic and social empowerment can be accelerated through the MSME sector. The study looks at the different obstacles that Indian women entrepreneurs must overcome and how MSMEs may help them do so. It also looks into how MSMEs affect women's employment, earning potential, and general socioeconomic advancement. The study also examines government programmes and policies that support women's involvement in the MSME industry. It also emphasises how crucial access to funding, skill development, and education are for female entrepreneurs. Using a mixed-methods approach, the study combines qualitative interviews with female entrepreneurs with quantitative data analysis. The results indicate that MSMEs can play a major role in empowering women by giving them access to chances for financial independence, skill development, and decisionmaking authority. In order to further strengthen the beneficial effects of MSMEs on women's empowerment in India, the study ends with recommendations for policymakers, MSME stakeholders, and female entrepreneurs.
The Igiogbe Custom as a Mandatory Norm in Conflict of Laws: An Exploration of Nigerian Appellate Court Decisions
Authors: Adesina Okoli Chukwuma Samuel , Yekini Abubakri , Oamen Philip
Published: October 2023

Under the Igiogbe custom of the Bini Kingdom of Edo State Nigeria, the eldest surviving son exclusively inherits the ancestral home of his deceased father. This custom is a mandatory norm in conflict of laws. Litigation on the custom has been described as a matter of life and death. There is a widely shared view among academic writers, practitioners, and judges that this customary law is absolute. Contrary to this popular view, this work argues that the Igiogbe custom can be displaced by statute and other customary or religious laws. To substantiate this position, this article examines all the reported appellate court decisions on the Igiogbe custom and other connected principles. It is often taken for granted that every Bini man is subject to customary law, thereby leading to the overriding application of the Igiogbe custom. Recent developments in case law suggest otherwise. There is a conflict of personal law question that is often ignored in most litigation concerning the Igiogbe. Careful consideration of this question can potentially lead to the application of other systems of succession law (statutory, religious, and other customary laws) other than the Igiogbe custom. Besides, these conflict of laws techniques and constitutional human rights norms can be used to strike the appropriate balance between competing interests and reasonable legitimate expectations of the deceased and their heirs.
Le Coran d’après l’Alcoran : Le référentiel coranique dans les Alcoran de Robert de Ketton et Marc de Tolède
Authors: Hanne Olivier
Published: October 2023

Dans leurs traductions latines du Coran, Robert de Ketton (1143) et Marc de Tolède (1210) ont cherché à transcrire comme ils pouvaient les mots par lesquels le livre s’autodésigne : kitāb, qurʾān, ḏikr, ḥikma, etc. Ils parviennent à transposer la nature éminente du Coran – qu’ils définissent comme un livre –, ses rapports avec d’autres textes religieux, comme l’Ancien Testament ou l’Évangile. Mais la tradition sunnite ayant à partir du IXe siècle canonisé le texte et conçu son inimitabilité, les deux hommes, qui n’ont pas une parfaite connaissance des notions d’ iʿjāz et de tanzīl, hésitent à traduire littéralement les termes définissant le Coran ou à les interpréter.
The Qur'an in the Commentaries on Dante's Comedy
Authors: Ribaudo Vera
Published: October 2023

Since the publication of Asín Palacios's theses, the issue of Arab sources in the Comedy has aroused considerable controversy among supporters and detractors of Dante's dependence on Muslim traditions. Rethinking the terms of the debate, scholars prefer nowadays to evaluate not only the role played by Latin or Romance intermediaries, but also the judgement that the Middle Ages expressed on Muslim religion. On the other hand, the perception of the Qur'an has remained insufficiently investigated. The Qur'an was known to the Christian Middle Ages as Lex Mahometi and therefore as a normative corpus which, being identified with the Prophet himself, ended up being denigrated through the usual tópoi of anti-Islamic propaganda. The present article will attempt to reconstruct the image of the Holy Book of Islam in the commentaries on the Comedy in relation to the concepts of heresy and schism.
Du Liber denudationis au baron de Münchausen, le voyage nocturne de Muhammad entre argument polémique et thème littéraire
Authors: Vigliano Tristan
Published: October 2023

L'ascension miraculeuse du prophète de l'islam vers Dieu ne fait pas l'objet d'un récit détaillé dans le texte coranique. Cependant, les récits de cette ascension prennent leur source dans le Coran et, dans l'esprit de nombreux auteurs chrétiens ou "occidentaux", ils sont inséparables du texte sacré des musulmans. L'article se concentre sur les récits du miʿrāj dans le Liber Scalae (et ses suites) traduit à l'initiative d'Alphonse le Sage, mais aussi dans la tradition polémique remontant aux Dialogues contre les Juifs de Petrus Alfonsi. Cette tradition perdure très longtemps : l'article la suit jusqu'au début du XIXe siècle, en se demandant dans quelle mesure son potentiel imaginatif s'est épanoui et combiné, par exemple, avec des motifs littéraires tels que celui du cheval d'ébène.
On Nicolas Criterion for the Riemann Hypothesis
Authors: Vega Frank
Published: October 2023

The Riemann hypothesis is the assertion that all non-trivial zeros have real part $\frac{1}{2}$. It is considered by many to be the most important unsolved problem in pure mathematics. There are several statements equivalent to the famous Riemann hypothesis. In 1983, Nicolas stated that the Riemann hypothesis is true if and only if the inequality $\prod_{q\leq x} \frac{q}{q - 1} > e^{\gamma} \cdot \log \theta(x)$ holds for all $x \geq 2$, where $\theta(x)$ is the Chebyshev function, $\gamma \approx 0.57721$ is the Euler-Mascheroni constant and $\log$ is the natural logarithm. In this note, using Nicolas criterion, we prove that the Riemann hypothesis is true.
Spatiotemporal variations and source analysis of VOCs in the environmental air of a typical pesticide remediation site
Authors: Li Xuwei , Ding Da , Xie Wenyi , Li Xuzhi , Wang Mengjie , Kong Lingya , Jiang Dengdeng , Deng Shaopo
Published: October 2023

As efforts to mitigate soil and groundwater pollution intensify nationwide, the incidence of volatile organic compound (VOC) contaminated sites has risen significantly. These sites exhibit continuous release and dispersion of VOCs during and after remediation/control processes, thereby adversely affecting the local environment and residents. This issue has emerged as a prominent concern in contemporary society. This study takes a representative pesticide-contaminated site as the research subject. The pollutant levels, composition, spatiotemporal distribution, and source characteristics of VOCs in the ambient air environment from 2016 to 2021 were investigated by statistical analysis, Geographic Information System (GIS) spatial interpolation, Positive Matrix Factorization (PMF) model, and characteristic ratio source. The results showed that the average mass concentration proportions of the five types of pollutants are: benzene, toluene, ethylbenzene, and xylenes (BTEX) (29.73%) > alkanes (26.85%) > oxygenated hydrocarbons (21.96%) > halogenated hydrocarbons (19.12%) > sulfides (2.35%). M-/p-xylenes and toluene were the main contributing pollutants of BTEX and appeared frequently in the lists of top three pollutant in the contribution rates at various sites. The average concentration range of VOCs inside (EA1∼EA5) and outside the site (CK1∼CK4) were 810.71–1437.24 μg/m³, and 784.47–1358.16 μg/m³, respectively. The spatial distribution and variation trend in concentrations of halogenated hydrocarbons and alkanes were similar, with both being high in the middle of the site in 2017 and high in the south in 2018, and then sharply falling to a lower level in 2019. The source analysis results showed that the main contribution sources of environmental air varied over time. There were three types of emission sources for VOCs during the monitoring periods in 2016 and 2018. The maximum contributions to total volatile organic compounds (TVOCs) in 2016 and 2018 were volatile sources of characteristic pollutants within the site (45.6%) and volatile source of fuel (70.6%), respectively. This study provides scientific evidence for the environmental management, planning, and VOCs pollution control of pesticide-contaminated sites in China.
Case Report: Fatal cytomegalovirus pneumonia after CAR-T cell therapy in the long-term follow-up
Authors: Cheng Jiali , Huang Jin , Cao Wenyue , Huang Liang , Mao Xia , Chen Liting , Zhou Jianfeng , Wang Na
Published: October 2023

Introduction

The rapidly developed CAR-T cell therapy has a unique profile of side effects, which perhaps has not been totally realized and understood, especially the late-phase toxicity. CMV is prevalent world-wide and establishes a life-long latency infection. It can lead to life-threatening complications in immunocompromised host, and little is known about CMV disease in patients after CAR-T cell therapy. Here, we report a patient who developed possible CMV-pneumonia three months after anti-CD19 and anti-CD22 CAR-T cell therapy for relapsed B-ALL, contributing to the understanding of severe side-effects mediated by virus infection or reactivation in patients receiving CAR-T cell infusion.

Case presentation

A 21-year old male patient with relapsed B-ALL received anti-CD19/22 CAR-T cell therapy, and achieved complete remission 2 weeks after the infusion. However, three months later, the patient was hospitalized again with a 10-day history of fever and cough and a 3-day history of palpitations and chest tightness. He was diagnosed with possible CMV pneumonia. Under treatment with antiviral medicine (ganciclovir/penciclovir), intravenous gamma globulin and methylprednisolone and the use of BiPAP ventilator, his symptoms improved, but after removing penciclovir his symptoms went out of control, and the patient died of respiratory failure 22 days after admission.

Conclusion

CMV infection/reactivation can occur in patients long after receiving anti-CD19/22 CAR-T cell therapy, and induce fatal pneumonia, which reminds us of the late side effects associated with immunosuppression after CAR-T cell infusion.
Targeting the melanoma-associated antigen CSPG4 with HLA-C*07:01-restricted T-cell receptors
Authors: Kropp Korbinian N. , Fatho Martina , Huduti Enes , Faust Marilena , Lübcke Silke , Lennerz Volker , Paschen Annette , Theobald Matthias , Wölfel Thomas , Wölfel Catherine
Published: October 2023

Intorduction

Chondroitin sulfate proteoglycan 4 (CSPG4), also known as high molecular weight-melanoma associated antigen, is expressed in melanoma but also other tumor entities and constitutes an attractive target for immunotherapeutic approaches. While recent preclinical reports focused on anti-CSPG4 chimeric antigen receptors (CAR), we here explore T-cell receptor (TCR)-based approaches targeting CSPG4.

Methods

The TCRs of two CSPG4-reactive T-cell clones (11C/73 and 2C/165) restricted by the highly prevalent HLA-C*07:01 allele were isolated and the respective αβTCR pairs were retrovirally expressed in CRISPR/Cas9-edited TCR-knockout T cells for functional testing. We also combined alpha and beta TCR chains derived from 11C/73 and 2C/165 in a cross-over fashion to assess for hemichain dominance. CSPG4+ melanoma, glioblastoma and lung cancer cell lines were identified and, if negative, retrovirally transduced with HLA-C*07:01.

Results

Functional tests confirmed specific recognition of CSPG4+HLA-C*07:01+ target cells by the αβTCR retrieved from the parental T-cell clones and in part also by the cross-over TCR construct 2Cα-11Cβ. Despite high surface expression, the 11Cα-2Cβ combination, however, was not functional.

Discussion

Collectively, 11C/73- and 2C/165-expressing T cells specifically and efficiently recognized CSPG4+HLA-C*07:01+ cancer cells which warrants further preclinical and clinical evaluation of these TCRs.
Using contribution analysis to evaluate health professions and health sciences programs
Authors: Choi Tammie , Sarkar Mahbub , Bonham Maxine , Brock Tina , Brooks Ingrid Ann , Diug Basia , Ilic Dragan , Kumar Arunaz , Lau Wee-Ming , Lindley Jennifer , Morphet Julia , Simmons Margaret , Volders Evelyn , White Paul J. , Wright Caroline , Palermo Claire
Published: October 2023

Introduction/background

Course evaluation in health education is a common practice yet few comprehensive evaluations of health education exist that measure the impact and outcomes these programs have on developing health graduate capabilities.

Aim/objectives

To explore how curricula contribute to health graduate capabilities and what factors contribute to the development of these capabilities.

Methods

Using contribution analysis evaluation, a six-step iterative process, key stakeholders in the six selected courses were engaged in an iterative theory-driven evaluation. The researchers collectively developed a postulated theory-of-change. Then evidence from existing relevant documents were extracted using documentary analysis. Collated findings were presented to academic staff, industry representatives and graduates, where additional data was sought through focus group discussions - one for each discipline. The focus group data were used to validate the theory-of-change. Data analysis was conducted iteratively, refining the theory of change from one course to the next.

Results

The complexity in teaching and learning, contributed by human, organizational and curriculum factors was highlighted. Advances in knowledge, skills, attitudes and graduate capabilities are non-linear and integrated into curriculum. Work integrated learning significantly contributes to knowledge consolidation and forming professional identities for health professional courses. Workplace culture and educators’ passion impact on the quality of teaching and learning yet are rarely considered as evidence of impact.

Discussion

Capturing the episodic and contextual learning moments is important to describe success and for reflection for improvement. Evidence of impact of elements of courses on future graduate capabilities was limited with the focus of evaluation data on satisfaction.

Conclusion

Contribution analysis has been a useful evaluation method to explore the complexity of the factors in learning and teaching that influence graduate capabilities in health-related courses.
Primary cilia: a novel research approach to overcome anticancer drug resistance
Authors: Lee Kyung Ho
Published: October 2023

Primary cilia are cellular organelles that consist of a microtubule skeleton surrounded by a membrane filled with cell signaling receptors. Many studies have shown that primary cilia are cellular antennas, which serve as signaling hubs and their assembly and disassembly are dynamically regulated throughout the cell cycle, playing an important role in regulating cellular homeostasis. Aberrant control of primary cilia dynamics causes a number of genetic disorders known as ciliopathies and is closely associated with tumorigenesis. Anticancer drug resistance is a primary cause of chemotherapy failure, although there is no apparent remedy. The recent identification of a relationship between anticancer drug resistance and primary ciliary dynamics has made primary cilia an important target subcellular organelle for overcoming anticancer drug resistance. Therefore, the research on primary ciliary dynamics may provide new strategies to overcome anticancer drug resistance, which is urgently needed. This review aims to summarize research on the relevance of primary cilia and anticancer drug resistance, as well as future possibilities for research on overcoming anticancer drug resistance utilizing primary cilia dynamics.