bluuebunny/crossref_metadata_2025 huggingface dataset:
Drug Development and Discovery (D3)
Authors: TUYISHIME Honnête Samuel
Published: July 2023

Abstract

Background and Objectives: In drug research and development whereby, the patient is the main focus, the mission is to overcome the disease and improve the quality of life. The process is designed to ensure that the newly produced medicines are SAFE, EFFECTIVE, and available for the patient in a brief period. As per FDA, drug development and discovery involve five main steps: discovery and development, preclinical research, clinical research, FDA review, and FDA post-market safety and monitoring.

With several disease outbreaks, drug discovery, and development has been essential tool in saving lives and ensuring the standard health status. Through research, it brings new drugs into the market against targeted diseases. With the aim of D3, the drugs are assessed under surveillance and monitoring to ensure their safety and efficacy.

Methods: Several methods have been generated to develop drugs in a brief period. Following the FDA process of drug development and discovery, a technological method is set per each step, these include computerized methods like High-throughput screening and Computer-based design used in designing a drug hit candidate and the use of pharmacological software to study the mechanism of action of the disease as well as the effectiveness and metabolism of the drug.

Results: Different studies show that research and development of drugs through drug discovery has been an essential tool in ensuring a better quality of life. It helps us understand the health condition allowing us to design drugs for newly occurring diseases and even previously untreatable conditions.

Conclusion: To play a vital role in saving lives and ensuring the best health status, it is important to understand the process of D3. FDA uses the data provided in the process to decide on different complications found in both prescribed and OTC drugs, hence controlling the serious adverse effects. This improves the process functioning as well as raises the quality of research and development.
Adsorption method using zeolite to produce fuel grade bioethanol
Authors: Hargono Hargono , Handayani Noer Abyor , Andani Sheila Dwifa , Wardani Ersa , Fisama Ulma Aqari , Seng Kevin Setiadi
Published: July 2023

Bitter cassava (Manihot glaziovii) has the potential to be converted into bioethanol. However, the distillation process can only purify it to 95% bioethanol. Therefore, it is necessary to carry out an adsorption process to obtain 99.8% bioethanol. This study aimed to investigate the effect of bitter cassava starch hydrolysis time and coral rock in the distillation column on glucose and bioethanol concentrations, respectively. Additionally, the study discussed the effect of adsorbent height (60, 80, 100, or 120 cm) in the adsorption column on bioethanol concentration. There are three main stages for obtaining fuel-grade bioethanol: (i) bitter cassava hydrolysis, (ii) bioethanol production, and (iii) bioethanol purification (distillation and adsorption). Zeolite 4A and natural zeolite were used as adsorbents in this study. The results showed that the best fermentation was obtained at 90 hours, resulting in an ethanol concentration of 13.82% (v/v), which could be purified up to 95.64% through distillation. Furthermore, further purification (adsorption) could extend fuel-grade bioethanol (99.62% and 98.42%). Another analysis also indicated that zeolite 4A was more feasible than natural zeolite for producing fuel-grade bioethanol.
METHODOLOGY OF THE HYBRID PROPULSION SYSTEM (DMP & DEP) FOR TRIMARAN TYPE FAST PATROL BOAT
Authors: Widyandari Aulia , Wahyudi Dedy
Published: July 2023

There are lot of research done to develop a patrol boat, from the modification of hull model until propulsion system equipment. For example the model ship type AMV (Advanced Marine Vehicle) was developed starting from the Catamaran, Trimaran and  Pentamaran model. Everything is aimed at obtaining the ship design that has the speed and stability. In addition to achieving high-speed vessel must be equipped with propulsion (Main Power) is great, that means the main engine dimensions, auxiliary equipments and fuel tanks is too large. Many Limitations of space on the ship's engine room trimaran vessel is the main obstacle in designing propulsion system. Beside that Patrol boat should have many missions speed, so propulsion system should be designed at that conditions.   Hybrid propulsion is a combination of Diesel Mechanical Propulsion (DMP) with Diesel Electric Propulsion (DEP). DMP system is connected directly to the propeller shaft (or through a reduction-gear). DMP has provide more efficiency rate of 95%. While DEP is only able to provide efficiency by 85% - 89% is slightly lower than DMP, but the DEP offers many advantages such as simplicity and suitability in the rotational speed settings, control systems, engine power production Redundancy, Flexibility in the design of equipments layout in engine rooms, noise, vibration and fuel consumption efficiency which affects the lower pollution.   Design of Hybrid Propulsion system can be satisfied and achieved the Power requirements and optimally at all speed condition of patrol boat. Therefore the author made using modeling Maxsurf-11.12 software and carried out various optimization of the choice of main engine, propeller and system conditions for fast patrol boat cruise.
Targets and Resources
Authors: Bankov Petar
Published: July 2023

Political parties in Central and Eastern Europe have become increasingly reliant on online tools to mobilize electoral support, a trend that seemed to have been further catalyzed by the COVID-19 pandemic. This article seeks to understand what factors determine the approaches parties took toward their online campaign. By looking into the online approaches of eight parliamentary-represented political parties in Bulgaria from the three parliamentary elections in 2021, the analysis shows that the type of online campaigns of parties depends, to a large extent, on the way parties use their resources, as well as their target audience. The basis for this conclusion is a qualitative analysis of media reports from the campaigns of the three elections. This finding suggests the need for a closer investigation on the interplay between party organization, use of online tools, and campaign appeals.
Development of Learning Media Based on Car Racing Games In Mandarin Subjects For Class X Pangudi Luhur Don Bosko High School Semarang
Authors: Prasetyo Anggi Novita Sari , Anggraeni Anggraeni , Supriatnaningsih Rina , Siregar Sheyra Silvia
Published: July 2023

By promoting fun and exciting learning, researchers develop a product that can be used in the teaching and learning process with a view to increasing the learning motivation of all students in learning and assisting eduacators in making it easier for an educator to deliver lessons. The purpose of this study is  1) to describe the result of the analysis of the needs of students and teacher on the development of car racing game media in Mandarin class in X class at Pangudi Luhur Don Bosko high school 2) to describe the prototype of the development of car racing game media in X class at Pangudi Luhur Don Bosko high school 3) to describe the result of expert validation on the development of car racing game media in X class at Pangudi Luhur Don Bosko high school developed by researchers.   The study uses research and development methods with five stages, namely 1. Potential problems, 2. Data collection, 3. Product design, 4. Product validation, 5. Product revision.  From the results of the analysis of interviews with subject teachers and analysis of needs questionnaires  student agree with development of  game- based learning media that are creative, effective and fun.  The validation result show that the car racing game-based learning media gets an average score of 87 from media expert and 87,5 from material expert, both of which show a score of 4 which means the media is very feasible to use. The media is then corrected according to suggestions and input from expert.
Effects of different flame-retardant treatments on the sound absorption properties of low-density fiberboard
Authors: Lee Min , Kang Eun-Chang , Lee Sang-Min
Published: July 2023

Internal finishing materials for large auditoriums or public facilities are regulated in South Korea to ensure their flame-retardant performance. Flame-retardant treatment of low-density fiberboard (LDF), an eco-friendly material, was performed to expand its use as a sound absorber by improving its fire safety. In this study, an LDF with a target density of 0.15 g/cm3 was prepared from radiata pine wood fibers and melamine–urea–formaldehyde resin, and recommended amounts of commercially available flame retardants (liquid type) were applied immediately after hot pressing. A powder-type flame retardant was blended with the resin used in LDF manufacture. The surface color and material changed partially depending on the flame-retardant type. The external application method slightly increased the moisture content and density, but it did not affect the physical properties of the LDF. The flame-retardant treatment reduced the emission of formaldehyde, as a scavenger. After treatment, the char area and char length of the LDFs decreased significantly to 9.42–23.64%, and 6.11–11.91%, respectively. The sound absorption performance of the flame-retardant-treated LDFs improved 4.08–9.11%, while their thermal-insulation performance remained unaffected. The flame-retardant-treated LDFs satisfy the regulation of flame retardancy, while maintaining sound absorption and thermal insulation functions.
The Application of Linear Programming into Production Schedule at Electrical Panel Company
Authors: Junaiddin Arsyad , Syaifuddin Deddy Takdir , Montundu Yusuf , Zaid Sudirman
Published: July 2023

This study aims to implement linear programming to produce an optimal production schedule to obtain the maximum profit for an electrical manufacturing company and deliver finished products to customers on time. Linear programming was applied as a tool to carry out optimal production planning [11] every month in a business calendar year, with the objective function of maximizing Profit [12], considering the limitations of existing resources within the company. The results showed that the proposed model's production schedule surpassed the company's target. Despite the target being eight panels per day or 1880 panels per year for 235 working days, the model delivers 2032 panels throughout the year, or 152 panels more significantly than the target set. Manufacturers produced twelve types of parent products. However, this study presented only five types of products as decision variables in the linear programming formulations. Due to time constraints and data readiness, it is hoped that the entire parent product type can be presented as a decision variable on the next occasion. This production planning model can be one of the solutions to support the Operational Management manager in solving the problems that usually occur in manufacturing, as well as a reference for the master production schedule for procuring material needs. This study contributes to planning electrical panel production scheduling to provide optimal planning and increase the knowledge base in operation.
GIS TOOLS IN THE VISUALISATION OF A LOCAL SPATIAL MANAGEMENT PLAN
Authors:   Department of Integrated Geodesy and Cartography, AGH University of Science and Technology, Mickiewicza 30, Krakow 30-059, Poland, Wasylik Joanna , Dębińska Ewa ,   Department of Integrated Geodesy and Cartography, AGH University of Science and Technology, Mickiewicza 30, Krakow 30-059, Poland, Maciuk Kamil ,   Department of Integrated Geodesy and Cartography, AGH University of Science and Technology, Mickiewicza 30, Krakow 30-059, Poland
Published: July 2023

Aim of the study: The main objective of the study was to analyse the possibility of using GIS tools for 3D modeling of data presented on local spatial development plans (LSMP) in the form of maximising the use of its provisions Material and methods: Publicly available LSMP for the analyzed scope were used in order to obtain the maximum building height for each section of the study area. Then, based on data obtained from the Open Street Map (OSM) and the database of topographic objects (BDOT10k), the areas on which construction or increase in the number of floors of existing buildings can take place were determined. Results and conclusions: The analyses obtained made it possible to determine the regions for which increased development is possible. This type of knowledge can be useful for facility owners, developers, and most importantly for public administration bodies to have knowledge about planning or possible elements in the MPZP that should be changed to prevent excessive building density. This could result, for example, in the possibility of obscuring the visibility of the sun for selected areas or closing air corridors in the city. Thus, this type of study allows a very simple way to visualise the maximum possible development on newly created local plans and other such analyses
Digital models and tools for diagnosing three-dimensional spinal deformity based on stereophotogrammetry data
Authors:   Perm National Research Polytechnic University, Shitoev Ivan , Stolbov Valerii ,   Perm National Research Polytechnic University, Murav'ev Sergei ,   Limited Liability Company “Yord Tech”, Nikitin Vladislav ,   Perm National Research Polytechnic University, Kloian Gaiane ,   Perm National Research Polytechnic University
Published: July 2023

Scoliosis is the most common orthopedic disease in children, which most often leads to disability. An urgent task of the current stage of the development of spinal deformity diagnostics is the search and introduction of new available methods of non-invasive safe diagnosis of spinal deformity at early stages, since existing diagnostic methods can detect spinal column deformity in three planes during the development of scoliosis, however, they have a number of limitations for use, since either X-ray radiation or diagnostic installations are used for their implementation, requiring complex installation in a separate room and training of operating personnel. In this regard, there is an urgent need to develop digital tools for the diagnosis of spinal deformity, which would neutralize these difficulties in clinical practice. The aim of the study was to develop a mathematical algorithm for identifying the deformation of the spinal column in the horizontal plane according to the photogrammetric evaluation of a three-dimensional model of the surface of the human back, which was obtained from the results of the operation of the original software for a personal telecommunications device. The algorithm for assessing spinal column deformity is a sequence of four stages: reposition of the coordinate system, stratification of the spine line into segments, calculation of the rotation of V-segments, separation of the V-segment ratios to the physiological bends of the spine and visualization of spinal deformity in the horizontal plane. The developed algorithm has a number of advantages compared to those developed earlier: it allows to identify the rotation of individual vertebrae and torsion of the spine as a whole, is implemented in relation to all vertebrae of the thoracic and lumbar spine, thereby providing the possibility of differentiated diagnosis of forms of spinal deformity - from posture disorders to scoliosis. The described algorithm is a separate part for modular software that allows diagnostics of spinal column deformity using a personal telecommunication device. This algorithm can be used in a comprehensive assessment of posture disorders and scoliosis, monitoring the dynamics of spinal column deformity in the rehabilitation process.
Analysis of socio-economic systems using quantumlike mathematical models based on status functions. Part II
Authors:   Saratov State University, Veshneva Irina , Bolshakov Alexander ,   Peter the Great Saint-Petersburg Polytechnic University
Published: July 2023

It is proposed to use quantum-like models with the use of status functions for mathematical modeling and subsequent analysis of complex socio-economic systems. The limitations of the methods of classical probability theory and mathematical statistics, as well as the theory of fuzzy sets, algorithms Mamdani, Suzuki and others for solving similar problems are described. A description of the main assumptions that are used in the mathematical modeling of socio-economic objects based on status functions is given. Examples are considered that describe the features of transition paths through intermediate states. An operator for the transition of a socio-economic system to various states, similar to the Hamiltonian, is presented. A spectrum of possible virtual trajectories is introduced to describe transitions to different states. A mathematical model based on status functions is proposed to describe the transition of the system to a measurable state. In the proposed Hamiltonian, the first term represents a subsystem of indica-tors, the second is an analog of the energy of indicators in the information environment. At the same time, terms are distinguished that are analogues of the energies of the system of two controlled indica-tors: interaction, kinetic and potential. The description of the results of mathematical modeling and the analysis of the interaction of two hypothetical indicators of the socio-economic system are given. The indicators are taken from the statistics of innovation indicators of one of the regions of the Russian Federation.
Mathematical modeling of preemptive management by the stages complex of administrative production
Authors:   Russian State Hydrometeorological University, Mironov Aleksey , Mironova Anna ,   Peter the Great St. Petersburg Polytechnic University, Burlov Vyacheslav ,   Peter the Great St. Petersburg Polytechnic University
Published: July 2023

In line with the fundamental reform of the Russia administrative legislation, this article discusses the synthesis of a geoinformation system for preventive management of the full cycle of production on affairs about administrative offenses. According to the Anokhin - Sudakov's theory of functional systems, the tasks of forming a structural image and synthesizing a mathematical model to manage the administrative process stages, as well as the tasks of substantiating the mathematical criterion and its structural and functional implementation to prevent violations of a reasonable time in production on affairs about administrative offenses, were set. According to the law of management object integrity preservation, it is obtained that the opposing side of the administrative conflict counteracts by the joint use of protective (geoinformation), target (enforcement) and providing (geolocation) management subsystems, each of which generates a different contribution to efficiency at the next stage of the administrative process. To create a mathematical model for making a managerial decision, adequately formalized for each stage of the administrative process, a natural-scientific approach to the synthesis of management in conditions of limited resources was used. An analytical dependence is determined, that integrates the functioning regularities of law enforcement, geoinformation and geolocation components of the management system at the stage of administrative practice. When concretizing it, the possibility of representing administrative production by Poisson transitions of the affairs flow about administrative offenses between the states of the administrative process stages in a continuous Markov chain is used. Through modeling a Markov chain by the Kolmogorov - Chapman's equations system the criterion of preemptive management existence of the administrative process stages complex is revealed, allowing under proper efficiency of administrative production to optimize the intensity of identification and neutralization of threats to ensure a reasonable time in the target, protective or providing subsystems of management. The structure and functionality of probabilistic transitions of the affairs flow about administrative offenses, including management procedures, in a Markov chain of administrative production are established by their network modelling based on accumulated observations of administrative statistics. Numerical studies of a synthesized model of preemptive management of administrative production have clarified the effects of disruption of transition processes between states of administrative practice on its efficiency.
DIFERENÇAS CONCEITUAIS E PEDAGÓGICAS ENTRE OS TERMOS “BRINCADEIRA” E “JOGO” NO BRASIL
Authors: MELLO MARIA APARECIDA
Published: July 2023

RESUMO: Este artigo é parte de tese produzida para concursopara o cargo de professora titular, cujo objetivo foi identificar as diferenças teóricas entre os conceitos de jogo e brincadeira, o papel de cada um deles nas aprendizagens das crianças e suas implicações nas práticas pedagógicas na Educação Infantil. A Teoria Histórico-Cultural fundamentou a pesquisa teórica por meio do método genético na metodologia, a partir do levantamento bibliográfico em livros e artigos científicos sobre “brincadeira” e “jogo”, e em autores russos apenas sobre o “jogo”. Os resultados apontaram a importância da diferenciação entre ambos os termos na Educação Infantil, bem como possibilitaram a proposição de que brincadeira seja a atividade principal de crianças de 0 a 3 anos, e o jogo, principalmente “jogo de papéis, como atividade principal de crianças de três a seis anos. A importância desses resultados para as aprendizagens das crianças corrobora a centralidade do aspecto lúdico nas atividades da Educação Infantil, distinguindo a brincadeira e o jogo em seus conteúdos, motivos, necessidades e especificidades para as crianças. Essa proposta de mudança da atividade principal na Educação Infantil indica, também, a necessidade de a brincadeira de 0 a 3 anos se desenvolver para jogos de papéis para crianças de 3 a 6 anos, uma vez que ambos são essenciais para que as atividades das crianças, também, se modifiquem de atividades involuntárias para voluntárias e volitivas. As implicações desta pesquisa para as práticas pedagógicas centram-se na necessidade de o corpo docente conhecer e passar a incluir os jogos de papéis nas atividades das crianças de 3 a 6 anos, auxiliando-as no desenvolvimento da autonomia, de atividades volitivas e autocontrole de suas atitudes.
Riesgo de depresión durante el embarazo en la atención prenatal de riesgo habitual
Authors: Silva Mônica Maria de Jesus , Serrano Tainah Barbosa de Moraes , Porcel Giovanna da Silva , Monteiro Bruna Borlina , Clapis Maria José
Published: July 2023

Objetivo: identificar el riesgo de depresión durante el embarazo en gestantes de riesgo habitual incluidas en el control prenatal y los factores asociados. Método: estudio transversal, realizado con 201 gestantes, en el consultorio de prenatal de riesgo habitual de una maternidad universitaria. Para la recolección de datos se utilizó un formulario electrónico que contenía un instrumento de caracterización y la Escala de Riesgo de Depresión del Embarazo. La variable dependiente fue el riesgo de depresión en el embarazo. El análisis estadístico se realizó mediante el cálculo de la razón de posibilidades (Odds Ratio) y utilizando las pruebas de Chi-cuadrado y exacta de Fischer. Resultados: entre las participantes, 68,2% tenían mayor riesgo de depresión durante el embarazo. Hubo asociación estadísticamente significativa entre mayor riesgo de depresión durante el embarazo y la variable ocupación (p=0,04), o sea, la ausencia del trabajo (OR = 2,00) duplicó la probabilidad de ocurrencia. Conclusión: la alta prevalencia de riesgo de depresión durante el embarazo destaca la necesidad de planificación, priorización e integración de la salud mental en los servicios de salud prenatal, especialmente en el ámbito de la Atención Primaria de Salud, por parte de los gestores de salud y de los formuladores de políticas.
Sofrimento psicológico em estudantes de enfermagem: relação com tempo de tela, alimentação e atividade física
Authors: Ramón-Arbués Enrique , Granada-López José Manuel , Satústegui-Dordá Pedro José , Echániz-Serrano Emmanuel , Sagarra-Romero Lucía , Antón-Solanas Isabel
Published: July 2023

Objetivo: determinar a prevalência de sintomas de ansiedade e depressão e sua associação com tempo de tela, dieta e atividade física em uma coorte de estudantes de enfermagem. Método: estudo descritivo transversal com amostra de 648 estudantes de enfermagem. Utilizou-se a Hospital Anxiety and Depression Scale, a versão curta do International Physical Activity Questionnaire e o Índice Espanhol de Alimentação Saudável. Foram realizados diferentes modelos de regressão linear múltipla para analisar a associação entre sintomas de ansiedade e depressão e tempo de tela, dieta e atividade física. Resultados: a prevalência de sintomas de ansiedade e depressão foi de 24,1% e 3,7%, respectivamente. O tempo prolongado de tela (>6 horas por dia), a baixa atividade física e a dieta inadequada foram associados de forma independente e significativa ao aumento da sintomatologia psicológica. Conclusão: a saúde mental dos estudantes de enfermagem pode ser beneficiada com a implementação de iniciativas que promovam estilos de vida saudáveis.
Efeito do parto assistido na ocorrência de desordens uterinas puerperais e na eficiência reprodutiva de vacas leiteiras mestiças
Authors: Coury Luís Fernando Faria , Campos Carla Cristian , Moraes Giovanna Faria de , Reis Natani Silva , Santos Ricarda Maria dos
Published: July 2023

Resumo Objetivou-se avaliar em vacas leiteiras mestiças que pariram um bezerro vivo, o efeito do tipo de parto (normal ou assistido) na ocorrência de desordens uterinas puerperais e no número de inseminações artificiais (IA) por concepção e taxa de prenhez 150 dias pós-parto (DPP). As vacas foram monitoradas durante o parto e o tipo de parto foi classificado como normal ou assistido. O parto normal não precisou de interferência humana, enquanto o parto assistido precisou de auxílio para retirada do bezerro por via vaginal. Foram registrados 825 partos, sendo 7 natimortos (0,85%) e 17 gemelares (2,06%). Foram analisados 801 partos simples, dos quais 766 (95,63%) foram normais e 35 (4,36%) foram assistidos. Foram avaliadas a ocorrência de desordens uterinas como a retenção de placenta associada com metrite (RP/ME) e endometrite clínica (EC). A ocorrência das doenças foi de 10,24% (82/801) para RP/ME, 12,86% para EC e 5.12% para RP/ME com CE. A maioria das vacas com parto normal tiveram puerpério saudável (73,89%), enquanto a maioria das vacas com parto assistido apresentaram desordens uterinas (74,29%). O número de IA por concepção foi semelhante nas vacas que tiveram parto normal ou assistido (2,39±0,08 e 3,00±0,43, P = 0,16). Não houve evidência de influência negativa do tipo de parto na taxa de prenhez 150 DPP de vacas leiteiras mestiças em lactação (P = 0,44). Vacas saudáveis apresentaram maior taxa de prenhez 150 DPP do que vacas afetadas por desordens uterinas no puerpério (51,65 vs. 42,92%). Vacas leiteiras mestiças com parto normal tiveram um puerpério saudável, comparadas às que tiveram parto assistido, por sua vez foram mais susceptíveis as desordens uterinas no puerpério. E vacas com puerpério saudável resultaram em maiores taxas de prenhez aos 150 dias pós parto.
Implementação de um sistema de ordenha e manejo da qualidade do leite bubalino em uma estação experimental no Rio Grande do Sul, Brasil
Authors: Domenico Vitória Leite Di , Paiva Ana Raisa , Jank Louise , Tomaszewski Caroline Andrade , Motta Amanda de Souza da
Published: July 2023

Resumo A produção de leite bubalino é uma atividade que tem crescido nos últimos anos, principalmente devido às características físico-químicas apresentadas pelo leite, que é o segundo mais produzido no mundo. O objetivo deste trabalho foi implementar um sistema de ordenha e monitorar os padrões de identidade e qualidade do leite bubalino produzido na Estação Experimental Agronômica da Universidade Federal do Rio Grande do Sul. Amostras foram coletadas quinzenalmente entre os meses de junho e novembro de 2021, totalizando dez coletas. As médias obtidas ao final do monitoramento foram de 4,84 g/100 g para gordura, 4,64 g/100 g para proteína, 5,06 g/100g para lactose, 15,26 g/100 g sólidos totais, 10,42 g/100g para sólidos não gordurosos, 0,18 g ácido lático/100 mL de leite para acidez, 1,037 g/cm3 para densidade, -0.533°C para índice crioscópico, 3.5 x105 cél/mL para contagem de células somáticas e 8.0 x103 UFC/ml para contagem padrão em placa. Não foram identificados resíduos de antibióticos e antiparasitários. Observou-se aumento de concentração e frequência de alguns ácidos graxos, após incremento de manejo nutricional dos animais, além da predominância dos ácidos palmítico (C16:0) e oleico (C18:1- cis (n9). Os resultados indicam que houve uma melhora significativa na qualidade do leite no período avaliado, decorrente das ações corretivas que foram estabelecidas, e a contagem padrão em placa demonstrou boas práticas agropecuárias na obtenção do leite e na higienização dos materiais, estando abaixo dos limites exigidos pela IN 76. O leite de búfala produzido pelo rebanho da Estação Experimental apresentou resultados físico-químicos e microbiológicos de acordo com a legislação, sendo uma matéria-prima a ser explorada na prospecção de produtos derivados.
Physical activity on anxiety symptoms during the COVID-19 pandemic: a systematic review
Authors: David Iaggo Raphael , Barbosa Elizabete de Oliveira , Felício Laís Francielle Francisca , Leao Luana Lemos , Souza Eric Hudson Evangelista e , Paula Alfredo Maurício Batista de , Silva Felipe de Oliveira , Machado Frederico Sander Mansur , Monteiro-Junior Renato Sobral
Published: July 2023

Abstract This systematic review aimed to investigate the effect of physical activity on anxiety symptoms during the COVID-19 pandemic. Three databases (PubMed; Scopus and Web of Science) were searched in the period from 2020 to 2022 the following base terms were used: “Physical Activity”, Exercise, Anxiety and COVID-19. Peer-reviewed, primary studies published in English, Portuguese and Spanish using valid and reliable measures were included. Eighteen studies met the eligibility criteria, of which 17 were cross-sectional, 2 were cohort studies. The number of participants ranged from 43 to 2,301, aged between 18 and 65 years or older. A decrease in PA practice or an increase in sitting time were associated with higher levels of anxiety symptoms. Additionally, participants who did not meet PA recommendations were more likely to experience moderate to severe anxiety symptoms. The results showed that physical activity is associated with the alleviation of anxiety symptoms during confinement in the COVID-19 pandemic.
Sobre a Mentalidade Africana: A Antropologia Colonial na África Portuguesa (1950-1960) e a Antropologia do Negro no Brasil
Authors: Pinho Osmundo Santos de Araujo
Published: July 2023

Resumo Nesse artigo proponho uma abordagem sobre a antropologia colonial portuguesa que leve em conta o debate sobre a mentalidade africana, como um capítulo do debate mais amplo sobre a “mentalidade primitiva”, central nas primeiras décadas do século XX para a antropologia social, inclusive para a antropologia do negro no Brasil. A pretensão, definida, a partir da leitura de fragmentos da produção antropológica da fase final do colonialismo português é interrogar essa determinação recíproca na fábrica ideológica colonial e no tecido da teoria antropológica para a ideia de uma mentalidade africana. Dito de outra forma, interroga-se como a prática antropológica no contexto colonial dos anos 1950 e 1960 articula-se com a teoria antropológica sobre a diferença cultural africana, entendida como possível de ser descrita como “primitiva”. Discuto, nesse sentido, material encontrado em fontes coloniais dos anos 50 e 60 do século XX, para discutir a própria ideia de “mentalidade africana” e o modo como está presente na teoria antropológica, nas políticas coloniais na África, e também na formação do interesse antropológico sobre o negro no Brasil .
Implementação da Rede de Cuidados à Pessoa com Deficiência: na periferia da governança de São Paulo
Authors: Ferreira Heloisa Adhmann , Mota Paulo , Bousquat Aylene
Published: July 2023

Resumo A Rede de Cuidado à Pessoa com Deficiência (RCPD) foi implementada no Sistema Único de Saúde (SUS) para expandir o acesso aos serviços às pessoas com deficiência (PCD). Uma vez que seu funcionamento depende de mecanismos robustos de cooperação e pactuação entre os entes federados, este artigo analisa a dinâmica da Comissão Intergestores Bipartite (CIB) de São Paulo na condução da implementação da RCPD. Realizou-se uma análise documental das atas da CIB-SP de 2011 a 2019. O referencial teórico se pautou na análise de políticas públicas, utilizando abordagem multidimensional a partir das dimensões política, estrutura e organização. Na dimensão política, as pautas centrais são referentes à responsabilidade dos entes federados e demandas originárias do Ministério da Saúde e Ministério Público. A dimensão estrutura ocorre prioritariamente por pautas protocolares de informes de credenciamento/descredenciamento. Já na dimensão organização, foram classificadas como centrais: avaliação dos serviços; necessidades populacionais; oferta, fluxos, regulação assistencial e dispensação de órteses, próteses e meios auxiliares. Conclui-se que, quando não induzida por atores externos, a discussão é protocolar, reduzida aos informes de credenciamento de ações e serviços e adquire centralidade com demandas de órgãos externos e com o surgimento de novos problemas de saúde pública.
LUMBAR LORDOSIS VARIATION ACCORDING THE TYPE OF POSITIONER USED IN LUMBAR ARTHRODESIS
Authors: Lomaz Mateus Bergamo , Felisbino Júnior Pedro , Dorneles Filho Sinval , Melo Lucas Lodomiro , Orcino Juliane Leite , Sanches Murilo Ribeiro , Cotrim Paolla Machado , Souza Gabriel João Francisco de , Morais Thiago Vinicius de A. , Silva Paulo Henrique Martins , Daher Murilo Tavares
Published: July 2023

ABSTRACT Objective: Evaluate the influence of the most used surgical positioners for lumbar lordosis (LL) in asymptomatic individuals. Methods: Cross-sectional study based on demographic data and radiographic parameters of asymptomatic individuals. For this study, 16 volunteers, 15 males, and one female were selected, and the average age was 24.6 years. They were submitted to lateral radiographs of the lumbar spine in orthostasis in use of the following positioners: gel cushion, gel cushion with hip extension, four-point Relton-Hall and Wilson-type positioner. Results: The mean LL in the orthostatic position was 58.76º, whereas in the gel cushion positioner it was 52.51; on the gel cushion with hip extension of 58.23º, Relton-Hall/4points 37.63º and, finally, on the Wilson-type positioner of 40.87º. An average reduction of 5.42º of the LL was observed when positioning on the gel cushion in relation to the orthostasis. In the linear regression analysis, the data presented statistically significant results (p<0.05), demonstrating that the L4-S1 segment influences 60% in LL. Conclusion: The positioner with gel cushion and hip extension reproduces an LL similar to physiological values. Relton-Hall and Wilson-type positioners with hip flexion promote hypolordotic positioning compared to basal lordosis in orthostasis. Hip extension alone generated a 5.96º increase in the subject’s lordosis. The L4-S1 segment has a 60% influence on the LL when the individuals are in the positioners. Level of evidence III; Controlled cross-sectional study.
The Impact of the Psychosocial Safety Climate on Safety Behavior and Satisfaction: Focused on VR-Trained Airline Cabin Crew
Authors:   The Korea International Trade Research Institute, Kim Mijung , Lee Yeonu
Published: July 2023

Purpose – The purpose of this study is to examine the influence of the policies and implementation of the psychosocial safety climate within airlines on cabin crew member safety behaviors and satisfaction through virtual reality (VR) training, with the aim of ensuring safe flights. Design/Methodology/Approach – This study was conducted to validate the established hypotheses and research models by employing 353 cabin crew members within a domestic company that provides VR training. Empirical research was executed using the SPSS 25.0 statistical package for data analysis. Findings – This study found that the psychosocial safety climate positively impacts the safety behavior of cabin crew, which is enhanced through airline VR training. Essential factors that promote organizational safety activities include management support and commitment, management priorities, organizational communication, and organizational participation and involvement. Moreover, managing the stress of flight duty-related cabin crews significantly impacts the relationship between safety behavior and training satisfaction. VR training helps improve organizational safety, and organizational efforts seem to encourage the active participation of employees in providing an environment where safe flights can be carried out. Research Implications – This study suggests the necessity of expanding and applying training programs using VR, not limited to VR training for cabin crew members, also considering the job characteristics of other departments, such as pilots and maintenance personnel. Also, this research explores methods for effectively managing human resources in airline cabin crews in accordance with the changed training methods, and provides reference materials for effectively conducting VR training in the future.
Research on the Influence of Experiential Marketing of Kids Cafe on Consumers’ Purchase Behavior
Authors:   The Korea International Trade Research Institute, Kim Yeong-Gil
Published: July 2023

Purpose – In recent years, with the rapid improvement of China’s economy, technology and consumption capacity, the children’s coffee shop industry has played an increasingly important role in China’s economy. Consumers’ demand for toys is also increasing, and experience marketing the resulting experience demand is also having an increasing impact on consumers’ purchasing behavior. Design/Methodology/Approach – This study takes the experience economy as the background, takes the Chinese children’s coffee shop as the research subject, and takes the experience marketing strategy model as the entry point to find out the problems existing in the marketing of the children’s coffee shop. Findings – This study comprehensively sorts out the content of strategic experiential marketing, and uses the method of SPSS statistical analysis and questionnaire survey to analyze the industry status quo of experiential marketing in children’s coffee stores. In-depth analysis was carried out, and the causal relationship between the five elements of sensory experience, emotional experience, thinking experience, action experience, and associated experience and consumer purchasing behavior was tested by regression analysis. Research Implications – The results are obtained. Theoretical inspiration. In terms of practical marketing, enterprises should deeply explore the influence of experiential marketing elements of children’s coffee stores on consumer purchasing behavior, so as to optimize marketing strategies, strive to provide feasible guidance for the development of the industry, and promote the operation of such small and medium-sized enterprises in China and development.
An IPA Analysis Study on Medical Tourism Service Quality: Focusing on Medical Tourism Employees in Bucheon City
Authors:   The Korea International Trade Research Institute, Han Ho-Sung , Um Ji-Young , Chae Hee-Won
Published: July 2023

Purpose – After breaking the three-year hiatus in medical tourism due to COVID-19, the medical tourism industry is looking forward to reopening. This study conducted an empirical study on the importance and performance of medical tourism service quality to provide implications in accelerating the revitalization of the medical tourism industry. Design/Methodology/Approach – Existing studies related to the service quality of medical tourism have been conducted mainly targeting foreign patients. In order to balance this point of view, 50 medical tourism employees in Bucheon city were set as targets. Then, IPA analysis on medical tourism service quality was conducted. Findings – The medical infrastructure and system, intensive service for foreign patients only, and professional manpower have excellent service quality, and areas to be improved are the foreign patient telemedicine system of the medical system and the foreign language homepage of the service system. In order to revitalize medical tourism, it is necessary to consider priorities in the relevant areas. Research Implications – This study is meaningful as data for comparison with previous studies on medical tourism service quality before COVID-19. In addition, research on service quality for medical tourism employees was conducted to balance the implications of medical tourism research.
The Dynamic Relationship between the NFT Index and Macroeconomic Factors in Korea
Authors:   The Korea International Trade Research Institute, Liu Ke-Qin , Bian Ai-Lian
Published: July 2023

Purpose – This study attempts to analyze the dynamic relationship between the NFT index and macroeconomic factors, and make effective suggestions using research methods in the field of management finance. Design/Methodology/Approach – The study sample was from January 2020 to March 2023. The variables used in the analysis were based on monthly time series data, measured on the basis of the Metaverse–NFT Index (MVNX) index released by Wavebridge Limited in Korea to reflect the growth trend of the NFT market, money supply, US dollar–won exchange rate, gross domestic product, consumer price index, and other macroeconomic indicators. The analytical tools in this study included a unit root test based on the VAR model, the Johansen cointegration Test, Granger causality test, impulse response analysis, and variance decomposition. These methods are very effective in analyzing time series data. Findings – The results of the analysis show that macroeconomic factors, such as money supply, exchange rate, GDP, and consumer price index are important sources of information in predicting the NFT index. Research Implications – The results of this study are expected to provide practical information for NFT users, virtual asset trading platforms, investors, and policymakers related to NFT ecology. Furthermore, this study’s findings are of great significance, being the first global study to explore the relationship between NFTs and macroeconomic factors.
Formulating a Blue Ocean Strategy to Revitalize the Hotel Industry: The Case of the Residence Hotel Industry in Korea
Authors:   The Korea International Trade Research Institute, Lim Sung-Taek
Published: July 2023

Purpose – The purpose of this study was to provide a systematic technique for building a blue ocean strategy for residence hotels using research methodologies on customer satisfaction aspects in marketing on a strategic canvas and an ERRC matrix. Design/Methodology/Approach – To do this, we conducted a survey among hotel visitors using questionnaire items and a self-administered data collection approach, with each item scored on a 5-point scale. Judgment sampling was utilized as the sample method. We then used the survey responses to generate an ERRC matrix using IPA analysis. Findings – According to the ERRC table, hotel attributes that fall under the Raise category include “cleanliness of rooms”, “hotel location”, and “cultural and convenience facilities around the hotel”. Hotel attributes in the Reduce category include “diversity of food and beverage outlets” and “interior decoration and design”, whereas hotel attributes in the Create category include “cultural events”, “creating cultural streets”, and “a family-friendly atmosphere”. The use of the survey results-based Blue Ocean Strategy in the formulation of innovation strategies can provide managers evaluating creative strategies and strategic generating approaches with objective and detailed suggestions. Research Implications – In the Create category, hotel attributes include “cultural events”, “creating cultural streets”, and “a family-friendly atmosphere”. This indicates that, in order to attract and maintain clients, residence hotels might separate themselves from other hotels by generating demand through the development of local cultural streets. Above all, it is vital to sell not only hotel rooms but also a warm and cozy environment reminiscent of a home.
Analysis of the Export Changes of Korea’s HS9031 Products Using a Constant Market Share Model
Authors:   The Korea International Trade Research Institute, Sin Sun-Young , Lee Kwang-Bae , Mo Soo-Won , Lee Cheol
Published: July 2023

Purpose – This paper aims to investigate the export competitiveness of the Korean HS 9031 product group from 2016 to 2021 by adopting two constant market share models. Design/Methodology/Approach – This study utilizes two constant market share models, CMSA and CMSB. CMSA consists of disaggregating export growth into three main components. These components are referred to as the national growth component, the product component, and the trading country component. CMSB decomposes the total effect into the scale effect, the competitiveness effect, and the cross effect. All data used in this study were taken from the UN Comtrade database and the Korea International Trade Association database for four digit HS items. Findings – This study shows that Korea has a competitive edge over Vietnam, the United States, Taiwan, and Mexico in the domestic market, but has a competitive disadvantage in their import markets, while for India, Korea has competitive edge at home, but has a competitive disadvantage in India’s market. Research Implications – The analysis suggests that approaches and policies that focus on import market share rather than a competitive edge in the domestic market are needed.
COEXISTENCE OF LICHEN PLANUS AND COVID-19
Authors: OĞUZ Işıl Deniz , AKŞAN Burak , YILMAZ Kıvanç
Published: July 2023

COVID-19 may cause some skin symptoms. Maculopapular

eruptions, erythema of acral areas with

vesicles or pustules, urticarial lesions, monomorphic

vesicular eruptions, truncal or acral livedoid or necrotic

lesions are the most commonly reported skin conditions.

There are a few case reports of lichen planus

following COVID-19 infection. We also would like to

present a patient with lichen planus after COVID-19

infection.
Multilingualism as a determinant of the multidimensionality of the Ukrainian world. Publication Review: Brogi Giovanna. Cultural Polymorphism of the Ukrainian World
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, NIKA Oksana
Published: July 2023

MULTILINGUALISM AS A DETERMINANT OF THE MULTIDIMENSIONALITY OF THE UKRAINIAN WORLD Publication Review: Brogi Giovanna. Cultural Polymorphism of the Ukrainian World. Kyiv: Dukh i Litera, 2022. 520 p.