bluuebunny/crossref_metadata_2025 huggingface dataset:
TRENDS OF COMMERCIALIZATION OF THE LATEST TECHNOLOGIES IN UKRAINE
Authors: TARASIUK A.V. , SHANDOVA Natalia , MIESHKOVA-KRAVCHENKO Natalia
Published: June 2023

Goal. The aim is to study the peculiarities of the development of commercialization of new technologies in Ukraine, generalization and deepening of methodological and organizational and economic principles of determining the economic efficiency of commercialization of new technologies. Method. To solve scientific problems used: comparative analysis of empirical data; abstract-logical generalization. Results. The tendencies of commercialization of the newest technologies in Ukraine in the conditions of uncertainty of the economic environment are studied in the work. On the basis of the conducted comparative analysis the conditions of success of commercialization of the newest technologies are defined. The problems of regulating the effective commercial activity of the latest technologies have been studied, and the expediency of its expansion has been substantiated. Scientifically substantiated conceptual bases and practical recommendations concerning the basic tendencies of development of commercialization of the newest technologies are developed. Scientific novelty. In the process of analysis, it was found that the most effective and efficient direction of STP implementation is the commercialization of new technologies. Practical significance. Some results and conclusions can be used by government agencies in drafting government programs to regulate innovation.
CURRENT TRENDS OF THE WORLD WHEAT MARKET: DEMAND AND SUPPLY
Authors: SKOROMNA О.
Published: June 2023

Goal. study of supply and demand for wheat grain on the world market, as well as highlighting the main trends and analysis of projected wheat prices at the end of 2022, taking into account the state of crops and projected yields in major exporting countries. Method. To achieve this goal used a wide range of general and special methods of scientific knowledge: dialectical method, graphic, trend, technical analysis, method of induction and deduction, analysis and synthesis, monographic. Results. The study revealed a downward trend in the supply of wheat on the world food market in the 2022/23 marketing year, which, according to experts, will significantly affect price growth and could cause a global food crisis. The reason for this situation is the decline in wheat production in major exporting countries, government restrictions on exports to some countries, weather conditions in France, the blockade of Black Sea ports by Russian troops in Ukraine. Thus, the dynamics of wheat prices in Ukraine shows that on May 9 the price of wheat fell to UAH 6,000 / t, but on May 16 it increased by UAH 500 / t, and on May 23 it fell below UAH 6,000 / t. In general, the slump in grain prices is very significant and reaches about 30% of the initial price. According to technical analysis, the forecast prices for wheat in December 2022 on the Paris Stock Exchange Euronext may reach 440 euros / ton, and on the Chicago Stock Exchange - up to 1360 c $ / bu. The scientific novelty lies in a comprehensive study of the situation on the world wheat market and highlighting the main trends in its development. The practical significance of the obtained results lies in the technical analysis of the wheat grain market on the two main world exchanges and the formulation of sound conclusions about the current price movement and further trend, support and containment lines.
Concreto de cimento Portland dopado com quitosana: propriedades mecânicas e microestrutural
Authors: Silva João Ricardo Pereira da , Silva Rafaela Oliveira Holanda da , Silva Andresa de Freitas , França Emanuel Laurertan Tavares , Hernández Eduardo Padrón , Farias Patrícia Maria Albuquerque de
Published: June 2023

RESUMO A construção civil exerce função importante no consumo de energia em todo o mundo e influência, de forma significativa, o consumo total de recursos naturais e as emissões de CO2. A utilização de materiais renováveis está intrinsecamente relacionada à pesquisa e à inovação. A reutilização, a reciclagem, bem como o desenvolvimento de novos materiais e a descoberta de novas aplicações para materiais renováveis já conhecidos, podem contribuir de maneira expressiva para o desenvolvimento sustentável. A quitosana (CS) é um biopolímero com uma estrutura química e características únicas aliadas à sua farta disponibilidade como derivado da quitina, fazem com que suas possibilidades de aplicação nos mais diferentes campos tecnológicos, tenha se expandido consideravelmente. No presente trabalho, a utilização da quitosana para produção de concretos por meio de teores ótimos é investigada. Os valores de quitosana incorporados na dosagem foram 0,1%; 0,3% e 0,4%, com relação à massa de cimento. Os diferentes concretos obtidos foram submetidos a ensaios de propriedades mecânicas e microestrutural. Os resultados mostraram que a microestrutura foi favorecida com a utilização da quitosana. Bem como, apresentaram resultados favoráveis à incorporação dos teores utilizados de quitosana (se desatacando as amostras com 0,1% de substituição), sendo positivos quanto às propriedades mecânicas para a maioria das técnicas utilizadas, o que indica fortemente que a quitosana pode ser considerada como material promissor a ser incorporado na produção de concreto.
Fatores associados ao near miss neonatal em uma capital do Centro-Oeste do Brasil
Authors: Modes Priscilla Shirley Siniak dos Anjos , Gaíva Maria Aparecida Munhoz , Andrade Amanda Cristina de Souza , Guimarães Lenir Vaz
Published: June 2023

Resumo Objetivos: estimar as taxas de near miss neonatal e investigar os fatores sociodemográficos, obstétricos, do parto e dos neonatos residentes em uma capital do Centro-Oeste. Métodos: estudo observacional de coorte de nascidos vivos de Cuiabá no período de 2015 a 2018, com dados dos Sistemas de Informações sobre Mortalidade e sobre Nascidos Vivos. Foi calculada a taxa de near miss neonatal conforme as variáveis sociodemográficas, obstétricas, do parto e dos neonatos. Modelo de regressão logística foi ajustado para analisar os fatores associados ao near miss neonatal. Resultados: a taxa de near miss neonatal foi 22,8 por mil nascidos vivos e as variáveis que apresentaram associação com o desfecho foram: idade materna de 35 anos ou mais (OR=1,53; IC95%=1,17-2,00), realizar menos de seis consultas de pré-natal (OR=2,43; IC95%=2,08-2,86), apresentação fetal não cefálica (OR=3,09; IC95%=2,44-3,92), gravidez múltipla (OR=3,30; IC95%=2,57-4,23), nenhum filho nascido vivo (OR=1,62; IC=1,34-1,96) ouum filho nascido vivo (OR=1,22; IC95%=1,00-1,48), parto em hospital público/universitário (OR=2,16; IC95%=1,73-2,71) e filantrópico (OR=1,51; IC95%=1,19-1,91)e trabalho de parto não induzido (OR=1,50; IC95%=1,25-1,80). Conclusão: a taxa de near miss neonatal foi de 3,04 casos para cada óbito, sendo que o near miss neonatal foi influenciado pelas características maternas, histórico obstétrico, tipo do hospital do nascimento e organização da assistência ao parto.
Factors associated with neonatal near miss in a Midwest capital in Brazil
Authors: Modes Priscilla Shirley Siniak dos Anjos , Gaíva Maria Aparecida Munhoz , Andrade Amanda Cristina de Souza , Guimarães Lenir Vaz
Published: June 2023

Abstract Objectives: to estimate neonatal near miss rates and investigate sociodemographic, obstetric, childbirth, and neonate factors residing in a Midwest capital city. Methods: observational cohort study of live births from Cuiabá in the period of 2015 to 2018, with data from the Sistemas de Informações sobre Mortalidade e sobre Nascidos Vivos (Mortality and Live Birth Information Systems). The neonatal near miss rate was calculated according to sociodemographic, obstetric, childbirth, and neonate variables. Logistic regression model was adjusted to analyze the factors associated with neonatal near miss. Results: the neonatal near miss rate was 22.8 per thousand live births and the variables showed an association with the outcome were: maternal age 35 years or older (OR=1.53; CI95%=1.17-2.00), having fewer than six prenatal consultations (OR=2.43; CI95%=2.08-2.86), non-cephalic fetal presentation (OR=3.09; CI95%=2.44-3.92), multiple pregnancy (OR=3.30; CI95%=2.57- 4.23), no live birth (OR=1.62; CI95%=1.34-1.96) or one live birth (OR=1.22; CI95%=1.00-1.48), delivery in public/university hospital (OR=2.16; CI95%=1.73-2.71) and philanthropic hospital (OR=1.51; CI95%=1.19-1.91) and non-induced labor (OR=1.50; CI95%=1.25-1.80). Conclusion: the neonatal near miss rate was 3.04 cases for each death, and neonatal near miss was influenced by maternal characteristics, obstetric history, type of birth hospital, and delivery care organization.
Associação Internacional de Enfermagem da Família: ferramenta com recursos para cuidados a famílias de migrantes ou refugiados
Authors: Lise Fernanda , Marvicsin Donna , LeMoine Debbie Sheppard , Krumwiede Norma , Johnson Yuuko Mabrey , Figueiredo Maria do Céu Aguiar Barbieri
Published: June 2023

RESUMO Objetivo: Relatar a experiência do Comitê de Práticas da Associação Internacional de Enfermagem da Família em relação ao desenvolvimento de uma ferramenta com recursos para os cuidados a famílias de migrantes ou refugiados como resposta à crise mundial de migrantes e refugiados. Métodos: Estudo qualitativo e descritivo. Relato de experiência que descreveu o desenvolvimento de uma ferramenta com recursos para os cuidados a famílias de migrantes ou refugiados. Resultados: O desenvolvimento dessa ferramenta foi embasado na literatura atual relacionada a avaliação e intervenção centrada na família, uma prática culturalmente sensível baseada nos pontos fortes familiares; em declarações que indicavam o posicionamento sobre as famílias de migrantes ou refugiados; e em organizações de enfermagem e saúde que abordaram a saúde da família refugiada. Conclusões: A disseminação dos recursos disponíveis na ferramenta pode auxiliar nas práticas de enfermagem, estimular o uso de abordagens adequadas em avaliações e intervenções e promover a resiliência das famílias enquanto elas passam pelo período de adaptação, proporcionando, assim, bem-estar e levando à cura de traumas e adversidades enfrentados pelas famílias no processo de migrar ou refugiar-se.
COVID-19 IN HEALTH WORKERS: AN ECOLOGICAL STUDY FROM SINAN DATA, 2020-2021
Authors: Romano Pedro Henrique , Hillesheim Danúbia , Hallal Ana Luiza Curi , Menegon Fabrício Augusto , Menegon Lizandra da Silva
Published: June 2023

ABSTRACT Objective: to analyze the epidemiological and occupational profile of health workers notified for COVID-19 in Brazil, in the years 2020 and 2021. Method: this is an ecological study, which used data from the Information System of Notifiable Diseases (SINAN) and the Annual Social Information List (RAIS), from the years 2020 and 2021. Sociodemographic and occupational variables were analyzed. The prevalence rates of COVID-19 in health workers were calculated, modeled by Poisson regression in the Stata 14 software. Results: in 2020 and 2021, 35,545 health workers were affected by COVID-19. A higher prevalence of the disease was observed in females (79.0%), between 30 and 49 years (65.5%) and in blacks and browns (41.4%). Higher rates were observed in women (793.9/100,000 in 2020), young workers (839.9/100,000 in 2020), non-whites (1,497.4/100,000 in 2020) and in northern Brazil, with 1,688.1 cases per 100,000 workers in 2020. Nursing professionals, physicians and physical therapists had the highest rates of the disease in 2020 and 2021. Conclusion: there was a difference between the sexes, as well as social, racial and occupational inequities that reflect the need to expand health surveillance measures in order to ensure greater prevention, protection and assistance to health workers.
Inquérito Nacional de Cobertura Vacinal 2020: métodos e aspectos operacionais
Authors: Barata Rita Barradas , França Ana Paula , Guibu Ione Aquemi , Vasconcellos Maurício Teixeira Leite de , Moraes José Cássio de , Teixeira Maria da Gloria Lima Cruz , Domingues Carla Magda Alan , Borges Maria Fernanda de Souza Oliveira , de Azevedo Roberta Nogueira Calandrini , de Oliveira Consuelo Silva , Oliveira Andrea de Nazaré Marvão , Canales Ivy Thereza , Nascimento Valdir , Queiroz Rejane Christine de Souza , Lima Luísa Helena de Oliveira , Ramos Jr Alberto Novaes , Barbosa Jaqueline Caracas , Mirabal Isabelle Ribeiro Barbosa , Meira Meiruska , Antunes Maria Bernadete de Cerqueira , Teixeira Maria Denise de Castro , Gurgel Ricardo Queiroz , de Carvalho Martha Suely Itaparica , Cesar Tayñana , Maciel Ethel Leonor Noia , da Gama Silvana Granado Nogueira , Luhm Karin Regina , Boing Antônio Fernando , Mengue Sotero Serrate , de Oliveira Sandra Maria do Valle Leone , Lima Jaqueline Costa , Teles Sheila Araújo , Caetano Karlla Antonieta Amorim , de Araújo Wildo Navegantes
Published: June 2023

RESUMO Objetivo: Inquérito nacional de cobertura vacinal aos 12 e 24 meses de idade foi realizado para investigar as quedas nas coberturas a partir de 2016. Métodos: Amostra de 37.836 nascidos vivos das coortes de 2017 e 2018 residentes nas capitais, Distrito Federal (DF) e 12 cidades com mais de 100 mil habitantes, acompanhados nos primeiros 24 meses por registros nas cadernetas de vacinação. Setores censitários foram estratificados segundo condições socioeconômicas, e o mesmo número de crianças foi incluído para cada estrato. Calcularem-se coberturas vacinais de cada vacina e coberturas completas aos 12 e 24 meses, doses aplicadas, válidas e oportunas. Fatores familiares, maternos e da criança associados à cobertura foram pesquisados. Os motivos para não vacinar analisados foram: contraindicações médicas, dificuldades de acesso, problemas no funcionamento do programa e hesitação vacinal. Resultados: Os resultados preliminares mostram que menos de 1% das crianças não foram vacinadas, as coberturas pelo esquema completo são menores que 75% em todas as capitais e no DF, as vacinas com mais de uma dose perdem cobertura progressivamente, há diferenças entre os estratos socioeconômicos, favoráveis aos estratos mais altos em algumas cidades e aos estratos mais baixos em outras. Conclusão: Houve realmente redução da cobertura vacinal em todas as capitais e no DF para as crianças nascidas em 2017 e 2018, denotando piora na execução do Programa Nacional de Imunizações durante os anos de 2017 a 2019. O inquérito realizado não mensurou os impactos da pandemia de COVID-19 que podem ter reduzido ainda mais as coberturas vacinais.
CREATIVE PRACTICES AND AFFECTIVE BONDS IN THE CLASSROOM: A NARRATIVE STUDY
Authors: Sánchez Sánchez María , Prados-Megías María-Esther
Published: June 2023

Abstract The life stories of two female teachers delve into the type of teaching practices during the democratic transition in Spain. The narrative biographical research, through the use of biographical accounts, investigates the decision-making and practices that made the classroom an emancipatory space. The analysis focuses on the type of creative practices, the basis of educational, collaborative and democratic action. Literary creation and theatrical works, together with the students, fostered autonomy, confidence and a love of learning. These innovative practices, for the time, can be considered today as disruptive practices which, together with the importance of affective relationships and the revaluation of artistic spaces, constitute the basis of pedagogical action.
Cartografia das tensões no cuidado em saúde mental a partir da ferramenta analisadora “usuário-guia”
Authors: Chiabotto Cristian da Cruz , Robinson Patrícia Genro
Published: June 2023

Resumo Ao partir da condução do método da cartografia, esta pesquisa buscou investigar, com trabalhadores e usuários de um centro de atenção psicossocial, os modos de invenção cotidiana do cuidado em saúde mental, considerando os efeitos da micropolítica do trabalho e o contexto pandêmico da Covid-19. O trabalho em saúde, nesse sentido, é uma produção micropolítica entre todos os atores envolvidos no território em que a Reforma Psiquiátrica acontece no cotidiano, perpassando por inúmeros desafios em um campo de forças e embates para a consolidação de um modelo de atenção psicossocial pautado no cuidado em liberdade, na cidadania e na autonomia dos usuários dos serviços de saúde mental. Para realizar a investigação, a cartografia se estabeleceu em dois atos: no primeiro, produziu-se, com um coletivo de trabalhadores de um centro de atenção psicossocial, a ferramenta ‘usuário-guia’, que pretende construir a narrativa do percurso de cuidado de um usuário; no segundo, construiu-se, juntamente com os usuários do mesmo serviço, seus percursos singulares na busca pelo cuidado em saúde mental.
Phylogeography of Oligosarcus acutirostris (Characiformes: Characidae): testing biogeographic hypotheses in the Northeastern Mata Atlântica freshwater ecoregion
Authors: Souza Vida , Oliveira-Silva Leonardo , Dutra Rayana Tiago , Camelier Priscila
Published: June 2023

Abstract The Northeastern Mata Atlântica freshwater ecoregion (NMAF) is recognized for the high degree of endemism of its ichthyofauna, whose evolutionary and biogeographic histories are still poorly understood. Oligosarcus acutirostris is a freshwater fish species endemic to the NMAF, which is distributed in coastal rivers and streams draining Bahia, Espírito Santo, and part of Minas Gerais states in eastern Brazil. Its widespread distribution in currently isolated river basins along the NMAF prompted this study, which aimed to understand what scenarios would be involved in determining its current distribution pattern, and to contribute to a better understanding of the biogeographic history of the NMAF. For this, mitochondrial and nuclear DNA sequences were analyzed based on samples from different localities along the species distribution, including its type locality. Overall, phylogeographic analyses indicate a strong genetic structure within the species evidenced mainly by the non-sharing of haplotypes between most of the basins analyzed. According to the AMOVA results, the current distribution of haplotypes is better explained by the Pleistocene coastal paleodrainages. The results are also used to test and complement a biogeographic hypothesis previously proposed for the drainages of the NMAF.
Effect of walking with blood flow restriction in elderly women with osteoporosis/osteopenia
Authors: Bittar Simoni Teixeira , Santos Heleodório Honorato dos , Oliveira Valéria Mayaly Alves de , Brito Ana Tereza de Sousa , Machado Ruri Miranda , Alves José Manuel Vilaça Maio , Cirilo-Sousa Maria Socorro
Published: June 2023

Abstract Introduction The preservation of bone mass in elderly women is associated with better levels of practice of systematic physical exercises. Aerobic training combined with blood flow restriction seems to be a new alternative that determines this process, but knowledge gaps are still observed when referring to exercise associated with blood flow restriction (BFR) and adaptations on bone variables. Objective To analyze the chronic effects of aerobic training with and without BFR on bone mineral density and bone biomarker osteocalcin concentrations in older women. Methods Thirty women were randomized into the following groups: walking on a treadmill at low intensity with BFR; moderate treadmill walking with no BFR; only BFR (no exercise) for 20 minutes, twice a week, for 24 weeks. Bone mineral density was measured before and 24 weeks after intervention. Blood serum osteocalcin concentrations were measured before, 12 and 24 weeks after intervention. Results There were no differences between groups in bone mineral density (femoral neck, p = 0.31; total femur, p = 0.17; lumbar spin, p = 0.06) and osteocalcine (W(2) = 0.27; p = 0.87) ouctomes after 24 weeks of intervention. Conclusion There was no difference between walking training, blood flow restriction only, or walking+blood flow restriction on bone mineral density and osteocalcin concentrations after 24-weeks of intervention in older women with osteopenia/osteoporosis.
SPINAL FRACTURES AND THORACOABDOMINAL INJURIES IN POLYTRAUMATIZED PATIENTS: EPIDEMIOLOGICAL EVALUATION
Authors: Antonelli Alan , Kulcheski Álynson Larocca , Sebben André Luis , Nanni Felipe Negreiros , Santoro Pedro Grein Del , Benato Marcel Luiz , Graells Xavier Soler i
Published: June 2023

ABSTRACT Objective: Establish the frequency of incidences, management, and description of the relationship between thoracic and abdominal trauma and spinal injury. Methods: Observational, retrospective study of quantitative analysis carried out through the analysis of medical records of patients who presented spinal fractures and associated thoracoabdominal injuries. The participants were treated at a reference hospital in trauma care in Curitiba-PR from 2019 to 2021. The data were from patients with spine fractures referring to gender, age, trauma mechanism, fracture classification, associated injuries, Frankel neurological scale, and proposed treatment. Results: There was a predominance of male patients (84.5%) and young, with a mean age of 37.3 years, victims of car accidents. The main vertebrae affected were the lumbar spine (36.8%) and thoracic spine (36.2%). The most prevalent associated injuries were extra vertebral and cervical spine fractures. The most observed thoracic injuries were hemothorax, chest contusion, and fracture of multiple costal arches, while the most observed abdominal injuries were kidney injury, hemoperitoneum/abdominal hematoma, and liver injury. Of the total patients analyzed, 68% had fractures with associated thoracoabdominal injuries. Conclusion: Abdominal and thoracic injuries are frequently associated with spine fractures, with an association of 14.6% and 53.4%, respectively. The production of knowledge on the subject contributes to creating action plans to optimize the management and reduce the morbidity and mortality of these cases. Levels of evidence III; Systematic Review.
Phylogeny of Species, Infraspecific Taxa, and Forms in Iris Subgenus Xiphium (Iridaceae), From the Mediterranean Basin Biodiversity Hotspot
Authors: Wilson Carol A. , Boosalis Zoe , Sandor Michael , Crespo Manuel B. , Martínez-Azorín Mario
Published: June 2023

Abstract— Iris subgenus Xiphium is a small group of taxa that occur in the Mediterranean Basin, a long-recognized biodiversity hotspot. Phylogenetic relationships among these Iris were reconstructed based on sequence data from 110 nuclear markers
(coding regions) and plastomes using Bayesian inference and maximum likelihood methods. Best trees based on plastome and combined datasets resolved Iris subgenus Xiphium and I. xiphium as not monophyletic while nuclear and all-gene (combined nuclear and plastid coding
regions) datasets resolved the subgenus as monophyletic but I. xiphium as not monophyletic. Topology tests indicated the alternative hypothesis of a monophyletic subgenus is not rejected by the combined dataset while a monophyletic I. xiphium is rejected. Topology tests also
showed the hypothesis of a polyphyletic subgenus is rejected by the nuclear and all-gene datasets, however, a monophyletic I. xiphium is not rejected by these two datasets. We hypothesize that the subgenus is monophyletic based on these analyses, morphology, and biogeography, and that
uneven patterns of missing data is a likely reason for topological incongruence among datasets. A previously suggested informal group within the subgenus was supported. Patterns of relationships among species suggest multiple exchanges between the African and European continents but also the
importance of the Strait of Gibraltar as a barrier to genetic exchange.
POWER GENERATION AND RECOVERY OF HIGHER HYDROCARBONS UTILIZING COLD ENERGY DURING LNG REGASIFICATION
Authors: Wong Shing-Hon , Xiao Gongkui , Zhang Dongke
Published: June 2023

Liquefied natural gas (LNG) is stored and transported at cryogenic temperatures below -162°C. Despite the significant potential of the ultralow-temperature energy inherent in LNG for various applications, it is frequently squandered during regasification. While previous studies have proposed utilizing LNG cold energy for power generation and hydrocarbon recovery, none have explored the combined applications of these processes. Therefore, this study aims to leverage LNG cold energy during regasification for simultaneous power generation and natural gas liquids (NGL) recovery. Different power generation configurations using the Rankine and Brayton cycles are reviewed and compared to identify the most suitable power cycles and working fluid candidates. Different configurations for NGL recovery are also examined to optimize the utilization of LNG cold energy. The preliminary results of the proposed system are obtained using Aspen HYSYS software, incorporating natural water sources at ambient temperature as the heat source. The proposed system effectively produces ethane and liquefied petroleum gas (LPG), meeting the required sales gas specifications while generating an overall net power output. Furthermore, this paper investigates the impact of ambient temperature on process efficiency, providing valuable insights into the system's performance under different environmental conditions.
Loss of the Secretin Receptor Impairs Renal Bicarbonate Excretion and Aggravates Metabolic Alkalosis in Mice during Acute Base-Loading
Authors: Berg Peder , Jensen Tobias , Andersen Jesper Frank , Svendsen Samuel L , Modvig Ida Maria , Wang Tobias , Frische Sebastian , Chow Billy K. C. , Malte Hans , Holst Jens Juul , Sørensen Mads Vaarby , Leipziger Jens
Published: June 2023

Significance Statement

During acute base excess, the renal collecting duct β-intercalated cells (β-ICs) become activated to increase urine base excretion. This process is dependent on pendrin and cystic fibrosis transmembrane regulator (CFTR) expressed in the apical membrane of β-ICs. The signal that leads to activation of this process was unknown. Plasma secretin levels increase during acute alkalosis, and the secretin receptor (SCTR) is functionally expressed in β-ICs. We find that mice with global knockout for the SCTR lose their ability to acutely increase renal base excretion. This forces the mice to lower their ventilation to cope with this challenge. Our findings suggest that secretin is a systemic bicarbonate-regulating hormone, likely being released from the small intestine during alkalosis.

Background

The secretin receptor (SCTR) is functionally expressed in the basolateral membrane of the β-intercalated cells of the kidney cortical collecting duct and stimulates urine alkalization by activating the β-intercalated cells. Interestingly, the plasma secretin level increases during acute metabolic alkalosis, but its role in systemic acid–base homeostasis was unclear. We hypothesized that the SCTR system is essential for renal base excretion during acute metabolic alkalosis.

Methods

We conducted bladder catheterization experiments, metabolic cage studies, blood gas analysis, barometric respirometry, perfusion of isolated cortical collecting ducts, immunoblotting, and immunohistochemistry in SCTR wild-type and knockout (KO) mice. We also perfused isolated rat small intestines to study secretin release.

Results

In wild-type mice, secretin acutely increased urine pH and pendrin function in isolated perfused cortical collecting ducts. These effects were absent in KO mice, which also did not sufficiently increase renal base excretion during acute base loading. In line with these findings, KO mice developed prolonged metabolic alkalosis when exposed to acute oral or intraperitoneal base loading. Furthermore, KO mice exhibited transient but marked hypoventilation after acute base loading. In rats, increased blood alkalinity of the perfused upper small intestine increased venous secretin release.

Conclusions

Our results suggest that loss of SCTR impairs the appropriate increase of renal base excretion during acute base loading and that SCTR is necessary for acute correction of metabolic alkalosis. In addition, our findings suggest that blood alkalinity increases secretin release from the small intestine and that secretin action is critical for bicarbonate homeostasis.
Is there a decline of Scientific Output in South African Dentistry: Addressing the Concerns and Nurturing Future Scientists
Authors: Wood Neil
Published: June 2023

I have received comments in general discussion with colleagues who ask me whether scientific progress in South African dentistry has declined over the last decade. Researchers and academics often point to a decline in the quantity and quality of this research, leading to concern and speculation. While there is no definitive data or statistics to support these claims, anecdotal information suggests that the quantity of dental research publications in South Africa have declined over the past few years. This decline may be due to a number of factors, including financial constraints, lack of resources, limited time available, and his recent COVID-19 pandemic, which has further strained the field. However, these are not a sufficient explanation for the decline and the dental community needs to take action to address this problem.
Athletic Conference Consideration for Adding New Sports Post-COVID
Authors: Milstein Sloane , Lanzillo Julie , Damon Zack
Published: June 2023

COVID-19 has impacted the sport industry across all contexts, including intercollegiate athletics. Specifically, research has found that the Collegiate Sport Addition Process (CSAP) to add or remove a sport for athletic departments in previous economic downturns must consider multiple factors. The current study builds on previous research by exploring the considerations of adding a sport through a buyer-seller interaction framework. Specifically, the current study explored whether sport governing bodies or coaching associations should attempt to sell their sport at the intercollegiate Conference level, rather than at the institution level. The current study used a survey to collect feedback from conference commissioners across the intercollegiate sport landscape. Through surveys and follow-up interviews, findings led to emergent themes of balance, viability, funding and revenue, and post-season opportunities as factors that conference personnel considered when deciding to add a sport. Theoretical and practical implications are discussed.
CUTAC for FFPEs v1
Authors: Henikoff Steven
Published: June 2023

For more than a century, Formalin Fixed Paraffin Embedded (FFPE) sample preparation has been the preferred method for long-term preservation of biological material. However, the use of FFPE samples for epigenomic studies has been difficult because of chromatin damage from long exposure to high concentrations of formaldehyde. Previously, we introduced Cleavage Under Targeted Accessible Chromatin (CUTAC), an antibody-targeted chromatin accessibility mapping protocol based on CUT&Tag. Recently, we showed that simple modifications of our single-tube CUTAC protocol are sufficient to produce high-resolution maps of paused RNA Polymerase II (RNAPII) at enhancers and promoters using FFPE samples. We found that transcriptional regulatory element differences produced by FFPE-CUTAC distinguish between tumor specimens and identify regulatory element markers with high confidence and precision. Our simple step-by-step workflow makes possible affordable epigenomic profiling of archived biological samples for biomarker identification, clinical applications and retrospective studies.
High-throughput phenotyping of green canopy area during nematode infection v1
Authors: Willig Jaap-Jan
Published: June 2023

Nematode migration, feeding site formation, withdrawal of plant assimilates and activation of plant defence responses have a significant impact on plant growth and development. Plants display intraspecific variation in tolerance limits for root-feeding nematodes. Although disease tolerance has been recognised as a distinct trait in biotic interactions of mainly crops, we lack mechanistic insights. Progress is hampered by difficulties in quantification and laborious screening methods. We turned to the model plant Arabidopsis thaliana, since it offers extensive resources to study the molecular and cellular mechanisms underlying nematode-plant interactions. We established through imaging of tolerance-related parameters that green canopy area was an accessible and robust measure for assessing damage as the consequence of cyst nematode infection. Subsequently, we developed a high-throughput phenotyping platform to non-destructively measure the green canopy area growth of 960 A. thaliana plants simultaneously.
IMPLEMENTATION OF THE QUIZIZZ APPLICATION AS A MEDIA IN ASSESSMENT OF ONLINE LEARNING TO GROW STUDENT LEARNING MOTIVATION IN ELEMENTARY SCHOOLS
Authors: Romadhon Kharisma , Oktavia Lusi , Irfan Irfan , Jannati Putri , Ultavia Anelda
Published: June 2023

Learning motivation is the key to success in teaching and learning assessment activities in elementary schools. However, learning assessment instruments so far tend to be monotonous and boring for students. The purpose of this research is to describe how the application of the Quizizz application which is a medium for conducting assessments in online learning, and to describe the increase in students' learning motivation through this Quizizz application. The research method used is qualitative with a descriptive approach, the results of interviews and observations are a data collection technique in this study. The research was carried out at Al-Azhar Islamic Elementary School, Cairo, Pagar Alam City, South Sumatra. The results of research in the field prove that the application of the Quizizz application, which is a medium in the assessment of the teaching and learning process, can foster interest and motivation to learn. This can be seen from the activeness and enthusiasm of student learning, competing to get high scores, and so on. Through the Quizizz application, students can learn while playing.
DEVELOPMENT OF A CONCRETE-PICTORIAL-ABSTRACT (CPA) TEACHING MODULE TO IMPROVE NUMERATION LITERACY FOR ELEMENTARY SCHOOL STUDENTS
Authors: Shafira Faza , Fitriani Andhin Dyas , Darmayanti Mela
Published: June 2023

This study aims to describe the design of the hypothesis and the feasibility of the Concrete-Pictorial-Abstract (CPA)-based multiplication teaching module to improve the numeracy literacy of elementary school students. The research method used is Design and Development (DD). This research procedure is Planning, Production, and Evaluation (PPE). This research result is a Concrete-Pictorial-Abstract (CPA) based teaching module on multiplication material in grade II Elementary School. The teaching modules have been validated by three experts: material experts, design experts, and linguists. The validation results from material experts get a percentage of 95%, design experts get a percentage of 89%, and linguists get a percentage of 92.5%. All validation results are included in the excellent criteria. The product was tested on students through a literacy ability test which was carried out through a pretest and post-test. The average result of the students' pretest scores is 50, and the average post-test results are 83. Thus, this teaching module is feasible and can improve students' numeracy literacy.
CREATIVE THINKING AND COLLABORATIVE ABILITY OF ELEMENTARY STUDENTS WITH THE IMPLEMENTATION OF THE STEM INTEGRATED PROJECT-BASED LEARNING MODEL
Authors: Herlina Ai , Nirmala Sri Dewi , Rahayu Ucu
Published: June 2023

This paper is motivated by the author's efforts to improve the quality of Human Resources (HR) in accordance with the demands/developments of the times. This research was conducted to (1) find out how the differences in creative and collaborative thinking skills through STEM-integrated project-based learning and the use of conventional learning models, (2) describe creative and collaborative thinking skills using STEM-integrated project-based learning models. This study uses a quantitative approach method. It was held at Gugus 4 Cibadak, Public Elementary School Pamuruyan (as the control class) and Public Elementary School Cilengo (as the experimental class). Creative thinking data collection is using posttest and pretest, while for collaborative ability data collection is by observation sheets. The results showed that (1) the creative thinking ability (mean pretest 32,14 for experiment class and 40,17 for control class, mean posttest 79, 29 for experiment class and 40,83 for control class) and collaborative ability of the class with STEM-integrated project-based learning were superior/got more significant results than the class that used conventional learning models, (2) students' creative abilities emerged into several indicators such as fluency, flexibility, original thinking, and elaborative thinking, (3) collaborative abilities appear in the field based on indicators of confidence, positive attitude, respect, giving encouragement, and building group spirit.
IMPROVING THE LISTENING ABILITY OF ELEMENTARY SCHOOL STUDENTS THROUGH THE USE OF AUGMENTED REALITY-BASED LEARNING MEDIA
Authors: Saputra Dudu Suhandi , Susilo Sigit Vebrianto , Mulyati Tita
Published: June 2023

This research is motivated by the low listening ability of elementary school students. The purpose of this study is to determine the improvement of listening skills of fifth-grade elementary school students by using augmented reality-based learning media. This study uses an experimental model with a pretest-posttest control group design with a sample of 60 students. The instrument used in this study is to use a listening ability test, besides that the test results are analyzed by looking at the differences in students' listening abilities between students who learn by using augmented reality-based learning media and students who learn by using conventional learning media. The results showed that (1) there was a very significant difference in listening ability between the experimental class and the control class, and (2) the listening ability of students who studied using augmented reality-based learning media was higher than students who studied using conventional learning media. Through the use of augmented reality media, learning activities can be more fun and meaningful so that students do not feel bored studying learning materials.
Analysis of Perceived Determinants in Customer Service Quality: Focused on A utomotive Air Conditioning Service C enters
Authors:   People&Global Business Association, Khonglumtan Tara , Srisattayakul Parinya
Published: June 2023

Purpose: The objective of this paper was to determine the actual needs of customers in 3 groups: passenger cars, buses, and truck refrigerators who bring their vehicles to the Service Center to be air conditioner repaired.
Design/methodology/approach: We investigated at how variables including service quality (technician skill, service process, and overall quality), customer satisfaction (facility, responsiveness, and satisfaction), and customer loyalty (repeat orders, loyalty) influence customer perceptions. The primary data comes from a questionnaire of 425 customers. Before being analyzed with Confirmatory factor analysis (CFA), it was first tested for reliability using Cronbach alpha, CR, and AVE, all of the questionnaires are reliable.
Findings: According to the CFA findings, customer perception has a 95 % confidence impact on customer satisfaction. Following that, a separate analysis of the 3 types of customers was conducted to determine the level of confidence in service quality. Ordinal logistic regression was used to conduct a statistical analysis for a Likert scale question, and it was discovered that customers of passenger cars and buses were more confidence and satisfied with their services than truck refrigerator.
Research limitations/implications: There were complexity and uncertainty on this study, but each one led to innovative thinking. Due to prior research, there were no additional studies conducted in the context of automobile, bus, or truck air conditioning repair services. The literature review is so challenging as a result. Given the respondents were drivers, their ideas and opinions may have been clouded during data collecting. Only concentrate on surveys for corporate owners or executives if precise data is required.
Originality/value: This focused for discrepancies between perceived significance and satisfaction in hopes of identifying managerial issues related to how well customers perceive the quality of service. It is demonstrated by considering the value of each service-related characteristic. Also, this study shows that CEOs should concentrate on creating service practices that will attract customers towards the service center.
Kalıp Yargı ve Ön Yargılı Çocuklar: Sosyal Bilgiler Dersi Bağlamında Bir İnceleme
Authors: AĞGÜL Ceren , YILMAZ Ferat
Published: June 2023

Araştırmada sınıf öğretmenlerinin görüşleri dikkate alınarak ilkokul öğrencilerinin sahip olduğu kalıp yargı ve ön yargılarının incelenmesi amaçlanmaktadır. Araştırma, kişilerin yaşam deneyimlerini nasıl yorumladıklarına odaklanan temel nitel araştırma deseni ile yürütülmüştür. Çalışmaya, Türkiye’nin farklı illerinde görev yapan 20 sınıf öğretmeni katılmıştır. Veriler, araştırmacılar tarafından geliştirilen “İlkokul Öğrencilerinde Görülen Kalıp Yargı ve Ön Yargılara İlişkin Yarı Yapılandırılmış Görüşme Formu” ile toplanmıştır. Elde edilen verilerin analizinde içerik analizi kullanılmıştır. Ulaşılan bulgulara göre ilkokul öğrencileri cinsiyet, etnisite ya da ırk, dil, din, yerleşim yerleri, meslekler, özel gereksinimli bireyler, dersler, sosyoekonomik düzey ve bireysel farklılıklar ile ilgili konularda kalıp yargılara sahiptir. Öğrenciler, kalıp yargılara sahip oldukları gruplar karşısında kaçınma, uzak durma, dışlama, tercih etmeme, iğrenme ve engelleme gibi davranışlar sergilemektedir. Bu kalıp yargı ve ön yargıların azaltılması için kalıp yargı ve ön yargıyı fark etme becerisine Hayat Bilgisi Dersi Öğretim Programında da yer verilmelidir. Böylece, ilkokul öğrencilerinin kalıp yargı ön yargılarının gelişip yayılması daha erken bir süreçte önlenmelidir.
NUMERICAL INVESTIGATION ON THE IMPACT OF INITIAL WATER SATURATION DISTRIBUTION ON HOT WATER FLOODING PERFORMANCE UNDER NON-ISOTHERMAL CONDITIONS
Authors: Ansari Md Irshad , Govindarajan Suresh Kumar
Published: June 2023

The heterogeneity in the spatial distribution of initial water saturation influences the performance of hot water flooding. The prospect of a reduction in oil recovery arises from the development of viscous instability. In the present study, a numerical simulation model has been developed by coupling heat transport, and multiphase flow in porous media integrated with the non-isothermal flow, and the numerical model has been verified with the existing analytical solution by Buckley and Leverett. The formation of a wavy temperature profile at the condensation front was found with a decreased depth of temperature penetration. The average rise of temperature is drastically affected by the spatial distribution of initial water saturation. The formation of viscous fingering was highly dominating in the reservoir, with initial water saturation randomly distributed and causing the front to move in an irregular pattern from the initial stage of the flooding. The heterogeneous reservoir with initial water distribution showed the earlier formation of viscous fingering than the homogeneous reservoir. The heterogeneity in the spatial distribution of initial water saturation had caused viscous instability, lower viscosity reduction, lower displacement sweeps efficiency, and higher residual oil saturation. The present study is limited to spatial distribution in initial water saturation to a certain degree of heterogeneity. The heterogeneity in the spatial distribution of initial water saturation highly impacted the production performance of hot water flooding. The present study provides an idea for the implementation and future development of hot water flooding in a randomly initial water saturation distributed environment.
INVESTIGATION OF CHROMITE ORE BENEFICIATION POSSIBILITIES WITH DIFFERENT GRAVITY CONCENTRATORS
Authors: Aras Ali , Taner Hasan Ali
Published: June 2023

The rapid development of industry increases the demand and importance of chromium. In this study, beneficiation possibilities of the representative chromite ore taken from the Tokat Province with a laboratory type jig, spiral concentrator, shaking table and multi gravity separator (MGS) were investigated. Appropriate particle size fractions were fed into each beneficiation device. Experimental studies were shown as a flow chart. The shaking table gave the best results for chromite beneficiation and a concentrate of 47.02% Cr2O3 grade and 94.29% recovery were obtained by using a -0.3+0.106 mm particle size fraction. It was observed that concentrates with saleable grade could be obtained as a result of the beneficiation of chromite ore with a spiral concentrator. The tailings obtained from the jig, spiral concentrator and shaking table were blended and scavenger experiments were carried out with an MGS to recover the remaining chromite in the tailings. 93.55% of the chromite in this blended sample was recovered with a grade of 34.96% Cr2O3. Hence, MGS seems to be the promising equipment for the beneficiation of tailings.
The Concept and Signs of Human Rights Activity
Authors: Chechelnitsky I. V.
Published: June 2023

The results of sociological studies and the dynamics addressed to the institutions of the state protection of the rights and freedoms of a person and a citizen unequivocally testify to the increase in the demand for human rights work in the Russian society in recent years. At the same time, it is necessary to take into account that in recent years, the legal system of Russia is undergoing a serious transformation. Domestic human rights protection activity, which after a quarter of a century of life in the course of globalization today is experiencing significant changes and will most likely continue to develop in the context of national values and traditions, is no exception. The article, based on the analysis of legislation and scientific works, offers author’s approaches to understanding the concept of legal protection activity and its features: volitional character, object and subject, goals and means. The conclusions formulated by the author are supported by the provisions of the current legislation and law enforcement practice of various institutions of state and non-state protection of human rights and freedoms.
Legal Protection of Russia’s Economic Sovereignty
Authors: Tanimov O. V.
Published: June 2023

This article analyzes threats to the economic sovereignty of Russian Federation. We examine the most important threats: economic sanctions, anti-crisis measures, which are aimed at protecting Russian economic sovereignty. In this article we analyze the measures of the Bank of Russia to stabilize the situation in the financial market, anti-crisis measures, which are aimed at supporting Russian businesses: general supportive measures, conclusions of Chamber of Commerce and Industry of the Russian Federation, supportive measures for public interest entities, small and medium sized businesses, the tourism business, supportive measures for land lease, changes in foreign exchange legislation, and others. This article investigates the fundamentals of anti-sanction legislation of Russian Federation: laws and regulation in accordance with which the legal protection of economic sovereignty of the state is implemented. There has been an increase of implementation of sanctions and criminalization of them in accordance with the amendments to 2012 act “On Measures of Influence on People Involved in Violations of Fundamental Human Rights and Freedoms and the Rights and Freedoms of Russian Citizens”.