bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of vascular endothelial growth factor in tuberculous meningitis
Authors: Kumar Devesh , Singh Deependra , Modi Tanish , Sharma Riya , Awasthy Anand Keshav , Shree Ritu , Goyal Manoj Kumar , Narang Dhawal , Chand Siddharth , Vyas Sameer , Sharma Kusum , Sharma Navneet , Gowda Rudresh , Goel Abeer , Ranjan Rajeev , Modi Manish
Published: September 2023

INTRODUCTION:

The status of vascular endothelial-derived growth factor (VEGF) in the pathogenesis of tuberculous meningitis (TBM) remains far from clear. We prospectively evaluated the role of serum and cerebrospinal fluid (CSF) VEGF in TBM.

PATIENTS AND METHODS:

This prospective study was conducted at a tertiary care center in North India from January 2018 to June 2019. Consecutive drug-naive patients (n = 82) of TBM diagnosed on the basis of modified Ahuja's criteria were included in the study. The results were compared with 49 control subjects (n = 49). Serum and CSF VEGF were done in all the cases and controls. Follow-up serum VEGF levels were done in 34 patients after 3 months of completion of antitubercular therapy. The VEGF levels were estimated using the human VEGF enzyme-linked immunosorbent assay kit.

RESULTS:

The mean age was 29.9 ± 13.1 years. The study group consisted of 33 (40.2%) men and 49 (59.8%) women. BACTEC MGIT960 was positive in 15 (18%) patients while multiplex tuberculosis polymerase chain reaction was positive in 73 (89%) patients. Levels of VEGF in serum and CSF of TBM patients were not elevated when compared to controls. There was no association between final outcome in TBM and decrease in serum levels of VEGF at follow-up.

CONCLUSION:

VEGF may not be playing a significant role in the pathogenesis of TBM. Future studies with larger sample size may clarify the status of VEGF further in TBM.
Microteaching
Authors: Thangaraju Pugazhenthan , Medhi Bikash
Published: September 2023

Nearly all teachers are forced into teaching and gain experience through time, but many do not feel adequately prepared for their fieldwork in their training program. Only solution which helps teachers and students is to connect theory to practice by microteaching. It is a strategy for acquiring teaching abilities on a smaller scale, in which teachers may practice previously learned skills as well as acquire new ones. The efficiency of microteaching may be predicted using feedback from participants. While preservice instructors benefit from microteaching and students themselves find it helpful, academics have not yet looked closely at the assignment itself to determine precisely what microteaching entails. As a result, this study aids in learning more about the interactional aspects of microteaching and the effect of it in both teachers and students.
CO2 fluxes at the water-atmosphere interface in fluvial environments: an overview of studies in Brazilian rivers
Authors: Machado Daniela Vasconcelos , Silva Júnior Gerson Cardoso da , Marques Eduardo Duarte , Silva-Filho Emmanoel Vieira
Published: September 2023

Recent advances in Brazilian scientific production on CO2 fluxes at the water-atmosphere interface in rivers were reviewed, including estimates of CO2 partial pressure and fluxes. A total of 17 studies were reviewed. We compiled information regarding the location studied, the methodology used by each author, and the values of CO2 partial pressure (pCO2), CO2 fluxes (FCO2), and gas exchange coefficient (k) found in each region. The results were spatialized and synthesized. The important role of fluxes in CO2 degassing and their influence on climate change, as well as the global lack of data on these environments, were the main motivations for this study. The information was scarce, and most studies are focused on the Amazon Basin. However, high-resolution mapping of CO2 fluxes, at the scale of micro basins and streams, proved to be scarce. We emphasize, therefore, the importance of further studies in the country including other hydrographic regions, and in high resolution. These studies would add to our knowledge of how natural and anthropic processes influence CO2 flux, in addition to providing better estimates in tropical river systems.

Keywords: climate change, CO2 emission, CO2 partial pressure.
The influence of climate parameters on fires in the Paraíba do Sul River valley, southeast Brazil
Authors: Oliveira Jaqueline Gabriele de , Massi Klécia Gili , Bortolozo Luana Albertani Pampuch , Cunha Ana Paula Martins do Amaral
Published: September 2023

Brazilian biomes have been experiencing an increase in fires during the whole year, but fires increase substantially during drier periods. Several indexes might be good indicators of the severity of the droughts, such as The Rainfall Anomaly Index (RAI), Standardized Precipitation Index (SPI) and the Vegetation Health Index (VHI). This study therefore aimed to understand the dynamics of climate, using some indexes and fires in Paraíba do Sul River Valley, Paulista portion, to verify whether fire is more likely to spread in hotter and drier years. We hypothesized that fire events are more frequent and burned areas are larger in hotter and drier years in the region. By conducting a cross-correlation analysis and separating the monthly data into dry and rainy seasons, it was possible to establish a correlation between climate parameters and fire. A significant correlation was found between RAI and fires in both seasons. Additionally, we observed that high occurrences of fire events and burning areas were more explained by RAI, VHI and SPI-3 in dry and wet seasons than by temperature and SPI-1, SPI-6 and SPI-12. We noticed a complex dynamic between fire events, burned area, the environment, and climatic variables. However, the studied indexes proved to be effective tools for detecting drought conditions in the region and their relationship to fire.

Keywords: burning, climatic indexes, Paraíba do Sul River Valley.
Study of the effectiveness of a ZnO–TiO2 formulation in the degradation of humic substances in mature leachate by solar photocatalysis Brazil
Authors: Nohara Nicoly Milhardo Lourenço , Izário Filho Helcio José , Siqueira Adriano Francisco , Aguiar Leandro Gonçalves de , Oliveira Gabriel Caracciolo Koenigkam de , Nohara Evandro Luís , Alcântara Marco Aurélio Kondracki de , Napoleão Diovana Aparecida dos Santos
Published: September 2023

Treatment of landfill leachate is an important environmental issue, especially in developing countries such as Brazil. Advanced oxidation processes (AOPs) have been considered interesting treatment alternatives. In this study, ZnO–TiO2 mixtures were incorporated into a paint polymer matrix and fixed onto supports. Paints were applied by overlapping coat layers on plates, resulting in high film thickness (600 ± 80 µm). Treatment of mature leachate by an AOP was conducted in a plug flow reactor connected to a stirred tank under solar irradiation. The objective was to evaluate the degradation of humic acid (HA) and fulvic acid + humins (FAH). The highest HA and FAH removal efficiencies were 62% ± 4.9% and 16% ± 4.2%, respectively. The kinetic model provided a coefficient of determination (R2) of 0.974. Rate constants for HA and FAH removal were 2.96 and 1.03 × 10−3 min−1, respectively. Statistical models for HA and FAH degradation had R2 values of 0.96 and 0.99, respectively. Both approaches indicated that HA degradation is greater at acidic pH and higher TiO2 concentrations. FAH degradation was favored by acidic pH and higher ZnO concentrations. Statistical models showed the same mean difference in conversion between replicate runs of HA and FAH, suggesting a uniform diffusion of fractions through catalysts.

Keywords: heterogeneous photocatalysis, humic and fulvic acid, landfill leachate treatment, titanium dioxide, zinc oxide.
Cellular senescence throws new insights into patient classification and pharmacological interventions for clinical management of hepatocellular carcinoma
Authors: Wang Hou-Hong , Chen Wen-Li , Cui Ya-Yun , Gong Hui-Hui , Li Heng
Published: September 2023

Pancreatic cancer (PanCa) presents a catastrophic disease with poor overall survival at advanced stages, with immediate requirement of new and effective treatment options. Besides genetic mutations, epigenetic dysregulation of signaling pathway-associated enriched genes are considered as novel therapeutic target. Mechanisms beneath the deoxyribonucleic acid methylation and its utility in developing of epi-drugs in PanCa are under trails. Combinations of epigenetic medicines with conventional cytotoxic treatments or targeted therapy are promising options to improving the dismal response and survival rate of PanCa patients. Recent studies have identified potentially valid pathways that support the prediction that future PanCa clinical trials will include vigorous testing of epigenomic therapies. Epigenetics thus promises to generate a significant amount of new knowledge of biological and medical importance. Our review could identify various components of epigenetic mechanisms known to be involved in the initiation and development of pancreatic ductal adenocarcinoma and related precancerous lesions, and novel pharmacological strategies that target these components could potentially lead to breakthroughs. We aim to highlight the possibilities that exist and the potential therapeutic interventions.
Comparison of ethanol-soaked gelatin sponge and microspheres for hepatic arterioportal fistulas embolization in hepatic cellular carcinoma
Authors: Yuan Guang-Sheng , Zhang Li-Li , Chen Zi-Tong , Zhang Cun-Jing , Tian Shu-Hui , Gong Ming-Xia , Wang Peng , Guo Lei , Shao Nan , Liu Bin
Published: September 2023

Pancreatic cancer (PanCa) presents a catastrophic disease with poor overall survival at advanced stages, with immediate requirement of new and effective treatment options. Besides genetic mutations, epigenetic dysregulation of signaling pathway-associated enriched genes are considered as novel therapeutic target. Mechanisms beneath the deoxyribonucleic acid methylation and its utility in developing of epi-drugs in PanCa are under trails. Combinations of epigenetic medicines with conventional cytotoxic treatments or targeted therapy are promising options to improving the dismal response and survival rate of PanCa patients. Recent studies have identified potentially valid pathways that support the prediction that future PanCa clinical trials will include vigorous testing of epigenomic therapies. Epigenetics thus promises to generate a significant amount of new knowledge of biological and medical importance. Our review could identify various components of epigenetic mechanisms known to be involved in the initiation and development of pancreatic ductal adenocarcinoma and related precancerous lesions, and novel pharmacological strategies that target these components could potentially lead to breakthroughs. We aim to highlight the possibilities that exist and the potential therapeutic interventions.
Marking; Standard Hose, Aircraft
Authors:   G-3, Aerospace Couplings, Fittings, Hose, Tubing Assemblies
Published: September 2023

This document establishes the industry standard practices for marking standard elastomeric hose used in aircraft manufacture and repair.
Adapting an English Corpus and a Question Answering System for Slovene
Authors: Šmajdek Uroš , Zupanič Matjaž , Zirkelbach Maj , Jazbinšek Meta
Published: September 2023

Developing effective question answering (QA) models for less-resourced languages like Slovene is challenging due to the lack of proper training data. Modern machine translation tools can address this issue, but this presents another challenge: the given answers must be found in their exact form within the given context since the model is trained to locate answers and not generate them. To address this challenge, we propose a method that embeds the answers within the context before translation and evaluate its effectiveness on the SQuAD 2.0 dataset translated using both eTranslation and Google Cloud translator. The results show that by employing our method we can reduce the rate at which answers were not found in the context from 56% to 7%. We then assess the translated datasets using various transformer-based QA models, examining the differences between the datasets and model configurations. To ensure that our models produce realistic results, we test them on a small subset of the original data that was human-translated. The results indicate that the primary advantages of using machine-translated data lie in refining smaller multilingual and monolingual models. For instance, the multilingual CroSloEngual BERT model fine-tuned and tested on Slovene data achieved nearly equivalent performance to one fine-tuned and tested on English data, with 70.2% and 73.3% questions answered, respectively. While larger models, such as RemBERT, achieved comparable results, correctly answering questions in 77.9% of cases when fine-tuned and tested on Slovene compared to 81.1% on English, fine-tuning with English and testing with Slovene data also yielded similar performance.
Grammatical and Pragmatic Aspects of Slovenian Modality in Socially Unacceptable Facebook Comments
Authors: Lenardič Jakob , Pahor de Maiti Kristina
Published: September 2023

This paper investigates the grammatical and pragmatic uses of epistemic and deontic modal expressions in a corpus of Slovenian socially acceptable and unacceptable Facebook comments. We propose a set of modals that do not interpretatively vary in their modality type in order to enable robust corpus searches and reliable quantification of the results. We show that deontic, but not epistemic, modals are significantly more frequent in socially unacceptable comments, and specifically that they favour violent discourse. We complement the quantitative findings with a qualitative analysis of the discursive roles played by the modals. We explore how pragmatic communicative strategies such as hedging, boosting, and face-saving arise from the underlying syntactic and semantic properties of the modal expressions, such as the modal force and clausal syntax.
Chrysoritis Butler (Papilionoidea: Lycaenidae: Aphnaeinae) – Part I: Molecular phylogenetic analyses of a South African genus of myrmecophilous butterflies
Authors: Quek Swee-Peck , Pringle Ernest L. , Heath Alan
Published: September 2023

The molecular data of Talavera et al. (2020) is re-analysed to provide a foundation for a taxonomic revision of Chrysoritis. A COI phylogeny recovers most of the Chrysoritis species as monophyletic, and a few as polyphyletic but supported by the CAD gene. In the thysbe clade, most species, despite occurring in sympatry with at least one other species in the clade, maintain distinctive wing facies and ecological identity without intermediate forms. Within the thysbe clade, which contains the majority of species, sister taxon comparisons based on the COI phylogeny suggest speciation has been predominantly allopatric and accompanied mostly by minor morphological change and sometimes also a change in male patrolling terrain and/or host ant species. The diversification of the thysbe clade and the taxonomic implications of our results are discussed.
Depiction of Shona marriage institution in Zimbabwe local television drama, Wenera Diamonds
Authors: Samanga T. , Matiza V.M.
Published: September 2023

Marriage is a highly celebrated phenomenon among the African people. It is one of the important institutions among the Shona and Ndebele people in Zimbabwe as expressed in the saying ‘musha mukadzi’ and ‘umuzingumama’ (home is made by a woman) respectively. However with the coming of colonialism in Zimbabwe, marriage was not given the appropriate respect it deserves. This has given impetus to this paper where the researchers in the study through drama want to bring out the depiction of marriage institution in a post -independence television drama, Wenera Diamonds (2017). This paper therefore, aims to show the impact of neo-colonialism on Shona marriage institution. The neo colonial period is characterised with the perpetuation of Western imperial interests through protocols of diplomatic relations, treaties and existing bilateral agreements which marked a new phase of relationships with former colonisers. The aim of this article therefore is to depict marriage institution in neo colonial Zimbabwe in Wenera Diamonds (2017), a Zimbabwean television drama. Using qualitative research methodology, the research employs content analysis to elucidate the depiction in the said performance. Guided by the Africana womanist perspective, the article argues that the indigenous knowledge needed for African social development is rendered irrelevant by a dysfunctional set of values of the western hegemony. Against that, the paper establishes that the depiction of marriage institution in Wenera diamonds is a reflection of imperialist colonial forces on the black person hence the need to go back to basics and resuscitate their culture.
Wisconsin District Administrators’ Decision-Making Approaches during COVID-19 Pandemic-Related School Closures
Authors: Elannani Hassan
Published: September 2023

This study sought to examine the decision-making approaches used by Wisconsin district administrators when addressing COVID-19 pandemic-related school closures. It also examined the factors that impacted their decisions to close the schools or keep them open, the stakeholders considered when making these decisions, and the learning formats and platforms used during school closures. The research thesis was that Wisconsin district administrators’ decision-making approaches during the COVID health emergency were more classical and shared than political and that they were driven primarily by the well-being of students and staff. A survey was emailed to all Wisconsin district administrators. The survey results showed that Wisconsin district administrators’ decision approaches were predominantly classical and incremental in nature and high in satisficing, mixed scanning, and shared decision-making. The garbage can and political approaches ranked the lowest. The results from the interview questionnaire revealed that all Wisconsin district administrators followed state mandates to close the schools but relied heavily on input from stakeholders before making any mitigation decisions or choosing any learning format. They prioritized the well-being of students, families, and staff when making such decisions. The primary factors taken into consideration by district administrators to decide on virtual or in-person learning included guidance from health authorities, number of infection cases, student learning, availability of technology, and community dynamics. District administrators facing epidemic health emergencies need to seek all stakeholders’ input on mitigation measures, but student learning should be the primary driver behind closing schools or going back to in-person learning.
Floccularia luteovirens, a new edible mushroom record for Turkish Mycobiota
Authors: KARADUMAN Yakup , YEŞİLYURT Faruk , UZUN Yasin , KAYA Abdullah
Published: September 2023

The edible mushroom Floccularia luteovirens (Alb. & Schwein.) Pouzar, is reported as a new record for the mycobiota of Türkiye, based on the identification of the samples collected from Bolu province. It is the first member of the genus Floccularia Pouzar in Türkiye. A brief description of the species is provided together with the suggested Turkish name and the photographs, related to the macroscopy and microscopy.
Avaliando a usabilidade de um jogo digital para o ensino de probabilidade por professores dos anos iniciais do ensino fundamental
Authors: Oliveira Júnior Ailton Paulo de , Barbosa Nilceia Datori
Published: September 2023

O objetivo desse trabalho foi avaliar as impressões sobre o jogo digital “Probabilidade em Ação”, em sua usabilidade, ou seja, os atributos de qualidade no contexto computacional que avalia a facilidade do uso da interface do jogo, de professores dos anos iniciais do Ensino Fundamental que ensinam matemática que participaram de um curso de extensão referente ao ensino de probabilidade. Essa avaliação foi baseada na aplicação do modelo MEEGA+ em suas quatro subdimensões: estética; aprendizibilidade; operabilidade; e acessibilidade. O estudo indicou que o protótipo do jogo digital, segundo esse grupo de professores, apresenta características que atendem as perspectivas do educador em sala de aula, ou seja, que são apresentados aspectos positivos relacionados à interface do jogo digital permitindo uma interação agradável e satisfatória com o usuário e possuindo atributos que facilitam a operação e controle, bem como os relacionados aos usuários aprenderem a jogá-lo de forma fácil e rápida.
Contribuições da Fenomenologia husserliana para a Educação Matemática
Authors: Wichnoski Paulo
Published: September 2023

Com caráter ensaístico, este texto enfoca a Fenomenologia husserliana e expõe algumas das suas possíveis contribuições para a Educação Matemática, enquanto área de pesquisa e ensino. Na perspectiva da pesquisa, as principais contribuições residem no alerta para que o pesquisador não caia na objetificação da realidade, na universalização da verdade e na ingenuidade científica. Na perspectiva do ensino, contribui com a possibilidade de os conteúdos da matemática serem concebidos como coisa intencionalmente percebida, e com a sensibilização para ver e valorizar os alunos nas dimensões intencional, temporal e cultural. Com a Fenomenologia, compreende-se que o ensino e a pesquisa são realidades existenciais ontológicas e que alunos e pesquisadores são seres capazes de constituir conhecimentos, o que pode contribuir para que a Educação Matemática seja um projeto de pesquisa e de ensino centrado na humanização da pessoa que se coloca em condição de abertura para o compreender, ensinar e aprender.
The risk for hemodialysis access failure in subject with COVID-19
Authors: BULUT Ali , GÜÇLÜ Aydın , BULUT Bekir
Published: September 2023

Purpose: Thrombotic complications have been reported in up to 30% of patients admitted to ICU for COVID-19. However, data concerning hemodialysis access failure in subjects with COVID-19 is limited. This study aimed to investigate the frequency of hemodialysis access failure and its determinants, especially with respect to COVID-19 status.

Patients and methods: This multi-center cross-sectional study was conducted among subjects undergoing permanent hemodialysis. Patients were divided into two groups, those with and without access failure. The primary outcome measures of the study were differences in patient characteristics, laboratory measurements and COVID-19 positivity between the two groups. The secondary outcome measure was defined as the identification of factors independently associated with hemodialysis access failure.

Results: Hemodialysis access failure occurred in 26 (12.2%) patients. When those with access failure were compared to those without failure, type 2 diabetes (76.9% vs. 50%, p=0.018), hypotension during dialysis (88.5 vs. 58.1%, p=0.006) and COVID-19 positivity (73.1% vs. 15.1%, p
Cogestão da Reserva Extrativista Acaú-Goiana: Análise de 15 anos de êxitos e desafios
Authors: Gomes de Oliveira João Paulo
Published: September 2023

Este artigo apresenta uma revisão qualitativa da literatura sobre a Reserva Extrativista Marinha Acaú-Goiana, criada em 2007 com o propósito de promover o uso sustentável e coletivo dos recursos naturais pelas comunidades pesqueiras nos estados da Paraíba e Pernambuco. O objetivo deste estudo é analisar a cogestão da Reserva Extrativista Acaú-Goiana após 15 anos de sua instituição (2007-2022), destacando seus progressos e obstáculos. Os resultados identificaram diversos obstáculos à cogestão, incluindo a vasta extensão territorial da reserva, a escassez de recursos humanos e financeiros do Instituto Chico Mendes de Conservação da Biodiversidade – ICMBio, os impactos causados por empreendimentos dos setores agroindustriais, destilarias e indústrias cimenteiras que estão em proximidade à área, bem como conflitos relacionados à sobre-exploração dos recursos pesqueiros e à degradação dos recursos hídricos. Diante disso, a revisão ressalta a importância de promover uma participação social contínua em todos os processos decisórios, adaptando os instrumentos e ferramentas de cogestão à realidade local e levando em consideração a história das comunidades, as práticas tradicionais de manejo, a cultura local e as formas de organização social dos beneficiários. Além disso, é crucial a elaboração de um plano de manejo para a Resex Acaú-Goiana, visando facilitar a organização e participação das comunidades beneficiárias na cogestão.
Die Stellung der Objektpronomina in frühen okzitanischen und katalanischen Texten im Vergleich
Authors: Hinzelin Marc-Olivier
Published: September 2023

The article stresses mainly the comparison of the position of the clitic object pronouns with respect to finite verbs in two languages from the (Eastern) Pyrenees, Catalan and Occitan. The position of the weak pronoun in relation to the finite verb in Old Occitan and Old Catalan shows interesting differences to the modern varieties of these languages and to Old French. Both languages allow, like contemporary European Portuguese, the positioning of the object pronoun directly after the finite verb in unmarked main sentences. Unlike in Old French this applies irrespective of verb-first-constructions with the verb in the absolute front position (socalled Tobler-Mussafia Law), where in all medieval Romance languages a postposition occurs.
Producció, difusió i divulgació de la ciència en català
Authors: Riera Carles
Published: September 2023

Within the scope of a global linguistic focalisation, the author analyses in this contribution the production, spread and popularisation stages of science in Catalan language, starting from two principals: the linguistic subsidiarity and the exclusive functions. He also refers to the (corpus and status) planification and to the scientists’ linguistic formation and evaluation. Seven suggestions encouraging the use of scientific Catalan conclude this contribution.
La paratextualitat en la traducció mediambiental de divulgació: els jocs de paraules i la intertextualitat
Authors: Bracho Llum , Turney Edmund G.
Published: September 2023

Environmental discourse appears in the USA in the mid-20th century, and comes to us through translation, especially in the form of popularising literature. This article focuses on the analysis of five ecologist handbooks and the respective translations into Catalan and Spanish. We analyse their paratextuality, as an example of cultural aspects found in this kind of text, and more specifically intertextual and linguistic puns found in the original texts. In this respect, we also propose a classification of puns and describe the translation strategies within these translated versions. Finally we analyse sociolinguistic issues related to each translation language and the relevance of these translated puns in the texts as a whole.
Un somni de festa modernista: La santa espina d'Àngel Guimerà
Authors: Soler Maridès
Published: September 2023

Summary: Guimerà’s most important plays were written primarily during the epoch of the Catalan Modernisme. Therefore, evident influences of this movement appear to a greater or lesser extent in his theatre works. However, the presence of many such elements in the comedy La santa espina (such as nature, fantasy, religiosity, catalanism and nationalism) argues that this play must be classified as representative of Modernisme. These typical modernistic features can be found in the plot, in the protagonists, in the mysterious settings the action takes place in, as well as in the music by Enric Morera, a Modernist composer, whose melodies, songs and sardanes count among the most important and emblematic in Catalonia of the beginning of the 20th century. [Keywords: Àngel Guimerà; La santa espina; Enric Morera; Modernisme; Catalan music theatre]
Un corpus col·loquial i dialectal del valencià: PARLARS
Authors: Montserrat Sandra , Segura Carles
Published: September 2023

Summary: The corpus PARLARS aims to document the colloquial not interfered Catalan (Beltran / Segura, 2017) before it disappears, owing to both the pressure of standard and especially linguistic contact with Spanish (Segura, 2003). It also wants to offer researchers adequate materials to develop studies of description and analysis of the linguistic variation of Catalan, especially the one related to functional (colloquial) and dialectal varieties. Finally, using data provided by the corpus, we try to test the hypothesis that languages function as conventionalized structures, as explained by Cognitive Construction Grammar (Goldberg, 2003; Taylor, 2012; Hilpert, 2014). This article presents the first phase of the construction of this corpus which consists precisely of defining its main characteristics, the working methodology and the transcription system, as well as the results obtained so far. Keywords: corpus, colloquial variety, variation, Catalan, Valencian, synchrony, Cognitive Construction G
Orientalisme i certesa d'Andorra: Aproximació als Haikús d'Arinsal d'Agustí Bartra
Authors: Donoso Isaac
Published: September 2023

Summary: Andorra appears, among some romantic images historically evoked, as the spiritual reservoir of the Pyrenees. The literary constitution of this ‘Andorran myth’ certainly represents an exercise towards orientalization, the Exotic within the verydomain of Catalan literature (balanced in some way with other traditions such as Alpinist literature). Agustí Bartra’s latest collection of poems subsumed in sixty poems the spirit of the myth through an Oriental genre (the haiku) and phenomenology. In this note we study the literary and philosophical keys to better understand this gigantic poetic exercise that gave to Andorra one of its immortal masterpieces.Keywords: Agustí Bartra, Andorra, haikus, orientalism, phenomenology
TO EVALUATE SENSITIVITY OF VARUNA AND GOKSHURA AGAINST β -
LACTAMASES RESISTANT AND SENSITIVE ATCC KLEBSIELLA PNEUMONIA
Authors: - Ajantha , Mohan P Nandesh , K.S Shashirekha
Published: September 2023

Currently efficacy of antimicrobial agents found to be restricted and thus the need of hour becomes the alternative
source that has antimicrobial activity and easily available. Multi-drug resistant Klebsiella pneumonia isolates are
major one among health setback, therefore in the current study ATCC 700603 Klebsiella Pneumonia strains were
collected and cultured and antibiotic bacterial sensitivity pattrens were observed on the strains with spectrum of
β-lactamase resistance and sensitivity. Ayurvedic drug possess various medicinal properties and are attributed
with the quality of Krimighna (anti-bacterial) but has specific drug for specific causative microorganisms. On further evaluation, therefore present study is undertaken on sensitivity of Gokshura and Varuna against ATCC
700603 Klebsiella Pneumonia by well diffusion method. The Study concludes that aqueous extract of Varuna is
better acting at lower concentration and alcoholic extract of Varuna act better at higher concentration Unlike to
Gokshura where alcoholic extracts of Gokshura act better at all concentrations compared to aqueous extracts
though it shows moderate to mild zone of inhibition at all concentration of aqueous extracts against ATCC
700603 Klebsiella Pneumonia.
CRITICAL ANALYSIS OF SHATKRIYAKALA W.S.R. TO VIDRADHI
Authors: Anil Kumar , - Geeta , Aruna K Dwivedi , Asit K Panja , Nisha Gupta , Rajesh Gupta
Published: September 2023

Objectives: Ayurveda is the science of life. There are two major goals of Ayurveda; the first is to maintain the
health of a healthy person by following Dinacharya, Ritucharya, and Sadvritta; the second is to treat the ailments
of diseased people. So, Shatkriyakala is going to help a physician in understanding the pathogenesis of a particular disease. This concept is described by Acharya Susruta in Sutrasthana Chapter- 21 (Vranaprashniya). The
word Shatkriyakala comprises three words, shat means six. Kriya means action or treatment & Kala means time.
So, the literal meaning of the word Shatkriyakala is six opportunities for treatment of any disease. Shatkriyakala
includes six stages of Doshas viz. Sanchaya, Prakopa, Prasara, Sthansamshraya, Vyaktavastha and Bhedavastha.
So, the term Kriyakala refers to the recognition of the six stages of disease progression. Data Source: Ayurvedic
texts, research journals, and databases. Review Methods: Various Ayurveda classics and research studies published in journals related to Kriyakala are reviewed and analyzed. Result: Evidence from various Ayurveda classics and published studies show that Shatkriyakala played an important role in the control and manage of the Vidradhi in its early stages. Conclusion: Analysis of classical references and various published studies of Shatkriyakala shows that in the initial phases, we can stop the manifestation of Vidradhi and manage it appropriately with
the minimization of its complications.
EXPERIMENTAL STUDY OF HARITAKYADI KWATH IN PITTAJA MUTRAKRICHHA (UTI IN PREGNANCY)
Authors: Kumar Akshay
Published: September 2023

Ayurveda is referred to as a holistic system of medicine and has been integrated in general wellness applications
in several countries. It deals with managing health by maintaining equilibrium of physiological constituents.
Pittaj Mutrakrichha is one of the diseases caused due to Mutravaha Srotodushti i.e equivalent to UTI. Symptoms
like dysuria, burning micturition and increased frequency of micturition are seen. Cases of UTI in pregnancy are
generally asymptomatic. E. coli is the offending organism in over 90% cases. The incidence during pregnancy
ranges from 2-10%, other pathogens include Enterococcus, Proteus mirabilis, Klebsiella pneumoniae and also
fungi, yeasts and viruses. Bacteriuria is typically present at the time of the first prenatal visit, and if an initial positive urine culture is treated, less than 1% of women develop urinary infection.
The topic i.e., antimicrobial effect of Haritakyadi Kwath was assessed in- vitro against most common microbial
agents associated with UTI.
I attempted the experimental study on Pittaja Mutrakrichha with herbal preparation named “Haritakyadi Kwath”.
Experimental study was carried on 2 different characterised strain of bacteria (E. coli, Enterococcus faecalis) and
characterised strain of yeast (Candida albicans).
Haritakyadi Kwath has been chosen to see the effect on the patients of Pittaja Mutrakrichha (UTI in pregnancy).
Haritakyadi Kwath consists of 5 constituents namely Haritaki, gokshur, amaltash, pashanbhed and yavasa.
On the basis of experimental study, it can be concluded that Haritakyadi kwath is efficient in producing significant improvement in Pittaja Mutrakrichha.
AN AYURVEDIC APPROACH FOR THE MANAGEMENT OF DAGDHA VRANA
(SECOND DEGREE BURNS) WITH VIKESHIKA BANDHANA – A CASE STUDY
Authors: Gupta C B Adivishwanatha , B J Gopikrishna , K R Sahanasheela , Patil Bhagyashri
Published: September 2023

Management of burn injury is a challenging task as it can lead to considerable amount of agony and disability for
the victims. An estimated annual burn incidence in India is 6-7 million. Ayurvedic medicines got much desired
boost for current & emerging challenges, it is crucial that Ayurvedic medicines are beneficial, must play their respective roles in promoting health & preventing or treating diseases. Sushruta pioneer of Indian surgery explained
Dagdha Vrana (burn) and its management in 12th Adhyaya of Sutrasthana. As the patients of Dagdha (Burn) are
increasing in society due to today’s stressful & busy lifestyle. The present study entitled “A Case Study of Vikeshika
for Local Application in the Management of Burn.” Treatments prescribed in modern medicine like chlorhexidine
acetate as bactigauze had proved their definite efficacy in the Burn management, but they have some limitations
like it can’t avoid eschar, hypertrophic scar, post burn contracture which harms as a cosmetically. So, to overcome
these deficiencies we can apply Vikeshika as local application in the 1st & 2nd degree burn. The clinical assessment
was done based on grading criteria with specific symptomology of Dagda Vrana like Vedana (pain), Srava (secretion), Vrana Varna (colour), Gandha (smell), eschar, discoloration, hypertrophic scar, and contracture. According
to observations and results, a conclusion has been reached.
EVALUATION OF KANCHNAR GUGGLU ALONG WITH MATRA BASTI OF BALA TAIL IN VATASTHEELA(BPH)
Authors: Kaushik Preeti
Published: September 2023

Vatastheela is a disease of Mutravaha Srotasa (urinary system) described in Ayurveda, closely resembles with
benign prostatic hyperplasia (BPH) of the modern medicine. Mutraghata has been defined as a syndrome of obstructive urinary pathology due to dearranged function of Vata Dosha, particularly Apana Vata. It occurs in advancing age mainly after 4th,5th decades of life, which develops gradually and then becomes severe to affect the
life of patient causing symptoms related to obstruction in urine flow. Conservative management with hormonal
therapy, open prostatectomy and TURP are the options available in modern medicine. In Ayurveda, the drugs
having Vata Kaph pacifying action, Shothahara (anti-inflammatory) and Mutrala (diuretic) are recommended for
its management.
A CRITICAL STUDY OVER THE ROLE OF DASAMULA IN DIFFERENT FORMS
AND DIFFERENT ROUTES OF ADMINISTRATION IN THE MANAGEMENT OF
SANDHIGATA VATA W.S.R. TO OSTEOARTHRITIS
Authors: Yadav Hemant , Basak Nabanita , Mahapatra P.B. Kar , Sharma V.D.
Published: September 2023

Disorders of the vata dosa are prevalent throughout the world, affecting all ages and ethnic groups. The principal manifestations are pain and impairment of locomotor function. This disorder may account for a quarter of all general practitioner consultations. In later life, vata roga are the single most important factor including disability and so have a major impact on health and social service resources. The lifestyle of man has become mechanical. The time and more desire have made the man unable to follow the swasthya niyamas, there by becoming victims of diseases. The man today even in his young adult age is suffering from the degenerative diseases like Sandhi-vata (Osteoarthritis) Prevalence of this disorder in certain elderly group is as high as 85%. World-wide osteoar-thritis is the most common articular disease of people 65years and older. There is a steady rise in overall preva-lence from age 30. The knee hip are the principal large joints affected and the principal sites of significant disa-bility. Knee osteoarthritis is more prevalent than hip osteoarthritis but taken together they affect 10-25% of those aged 65years.Community survey data in rural and urban areas of India shows the prevalence of osteoarthritis to be in the range of 17-60.6%.Prevalence of osteoarthritis amongst elderly in rural areas of Amritsar was 60.6% while it was 17% amongst the elderly of rural areas of Wardha [Maharashtra]. In Aligarh the prevalence of oste-oarthritis is 30.2%. Different texts of Ayurveda have claimed that Dasmula is a potent anti-inflammatory and has an analgesic property which is used in the treatment of degenerative diseases as balya, vrisya and vata hara agent. Besides this Dasmula have actions like Vata hara, Vedana sthapana (Analgesic) and Sopha nasaka (anti-inflammatory) actions. So, in present study Dasmula kashaya and Dasmula tail have been taken as remedies of sandhivata or osteoarthritis. To evaluate their efficacy on set problem. In the present research project, a clinical trial has been performed over establish case of sandhivata or osteoarthritis. Where group –A patients have been treated with Dasmula kashaya as a kashaya pan and along with Abhyang by Dasmula tail. Group- B, patients treated with matra vasti and Abhyang by Dasmula tail. Group-C, patients treated with Dasmula kashaya as kashaya pan, Dasmula tail as a matra vasti and Abhyang, simultaneously for 30 days. After observation and analysis of data a conclusion has been made on the efficacy of Dasmula in the form of kashaya pan, matra vasti and abhyanga.
A COMPARATIVE STUDY OF APAMARGA (ACHYRANTHES ASPERA LINN.) PANCHANGA LEPA & APAMARGA PANCHANGA CHURNA ALONG WITH LEPA IN THE MANAGEMENT OF DADRU
Authors: Choudhary Tarun , Mishra Shiromani
Published: September 2023

Skin is the most important outermost covering of the human body, as it protects the body from invading pathogens. There is an increase in incidences due to poverty, unhygienic environmental conditions, poor sanitation,
improper skin care, malnutrition etc. In Ayurveda all skin diseases are classified under a broad heading “Kushta”.
Dadru is one among Kustha. Dadru is caused by vitiation of Kapha and Pitta Dosha, with clinical features like
Kandu, Raga, Daha, Pidika, Utsanna Mandala and Rookshata. In Ayurveda so many drugs are mentioned in the
treatment of the Dadru, among them Apamarga Panchanga Churna is selected. It has Katu, Tikta Rasa, Laghu,
Ruksha, Tikshna Guna, Ushna in Virya, Katu in Vipaka and also having properties like Kapha-Vata Shamaka. In
this clinical study Apamarga Panchanga Churna and Lepa has shown statistically significant improvement in
Kandu, Pidika, Utsaanmandal, Daha, Raga, Rookshta etc.
A REVIEW OF PANCHAKARMA THERAPIES (BAHYA AND SHODHANA) FOR PAKSHAGHATA
Authors: Medidar Asharani , R Manu.
Published: September 2023

"Pakshaghata" refers to a condition similar to hemiplegia or paralysis affecting one side of the body. According to Ayurveda, Pakshaghata is primarily caused by an imbalance of the Vata Dosha, which governs movement and communication in the body. The vitiated Vata Dosha affects the nerves, leading to impaired motor and sensory functions on one side of the body. The Ayurvedic treatment of Pakshaghata focuses on restoring the balance of Vata dosha and promoting the rejuvenation of affected tissues. The treatment approach may include Panchakarma therapies like – External therapies – Abhyanga (Oil Massage), Swedana (Sudation), and Shodhana (Purificatory) Procedures like Virechana (Purgation), Basti (medicated enemas), and Nasya (Nasal Medication). In the present article, we have tried to review the studies on Pakshaghata published and accessible through May 2023. Studies included Randomized and Non-randomized clinical trials.
A COMPARATIVE CLINICAL STUDY ON THE EFFICACY OF SADHYO VAMANA IN TWO DIFFERENT KAALAS IN URDHWAGA AMLAPITTA W.S.R. TO GAS-TRO-OESOPHAGEAL REFLUX DISEASE
Authors: G V Amulya , Borannavar Shaila , Rohidas Tejali Chandrakant
Published: September 2023

Amlapitta is a condition where Pitta becomes vidagdha which is a deviation from normalcy. This Vidagdha Pitta is more of amla rasa with increased dravatva and when it attains urdhwa gati, produces symptoms like amla udgara, hrit daha, kantha daha, hrillasa, etc. and is called Urdhwaga Amlapitta. In contemporary science, the symptoms are explained under a condition called Gastro-oesophageal Reflux Disease. The condition of Urdhwaga Amlapitta fulfils all the criteria required to be treated with Vamana. Sadhyo Vamana means to elimi-nate vitiated Dosha through the oral route quickly. It requires minimal to no Purvakarma. One of the purposes of the study was to see if Sadhyo Vamana will suffice in combating Urdhwaga Amlapitta and the other was to see if Sadhyo Vamana is equally helpful when administered as and when the symptoms of Urdhwaga Amlapitta de-velop or aggravate, without having to wait for Kapha kaala for the same. For the present study subjects were randomly selected from the OPD and IPD of Shri Jayachamarajendra Institute of Indian Medicine Hospital (Teaching Hospital of G.A.M.C.) Bengaluru. With this study, it can be concluded that Sadhyo Vamana can help bring down the symptoms in Urdhwaga Amlapitta. There was significant improvement in symptoms like Tik-ta/Amla udgara, Hrid- Kantha daha, and Trishna. There was no improvement in Aruchi and Trishna. ESR and Hb% in both groups improved considerably and they were slightly better in Group A. Overall improvement in Group A was 18.65% better than in Group B. It can be concluded that Sadhyo Vamana can be carried out even in later parts of the day to bring down the symptoms in Urdhwaga Amlapitta. However, when it is performed in Kapha kaala, it gives better results.
THE CORRELATION BETWEEN SHADARASA AND MANAS AROGYA.: A REVIEW
ARTICLE
Authors: Bhusewar Minal Dipak , Vaijanthrao Sudewad Savita
Published: September 2023

Ayurveda deals with both physical as well psychological disorders. According to Ayurveda there are two origins
of diseases, Sharir (Body) and Mana. Combination of Sharir, Indriyas, Satva and Atma is the living body according to Ayurveda. Mana / Satva is an important factor to manifest psychological disorders. In the present era, 1 in
every 8 people in the world live with mental disorders. Since 2020, the no. of people living with psychological
disorders rose significantly, because of Covid-19 pandemic. So, it’s more important to maintain mental health.
According to Bhagvad geeta, it is stated that nourishment of Mana/ Satva is done by Ahara. Also, according to
Ayurveda, Panchadnyanendriyas are nourished by Ahara. In this sage old wisdom, it is mentioned that Ahara
should consist of Shadrasa i.e., six types of taste. These Shadrasas not only have an effect on Sharir bhavas but
also on Mana/ Satva. So, it is important that one should know the effect of Shadarasas on Mana and effect of
excessive intake of each rasa, so that this will help to cure the Manas Vyadhi and to maintain equilibrium of Mana/ Satva.
ROLE OF ULATKAMBAL (DEVIL’S COTTON) ON DYSMENORRHEA
Authors: Kumari Bharati , Singh M.P. , Shreebhagwan Singh Vaidya
Published: September 2023

A plant, due to its morphological appearance of the flower named Pishacha karpas. It’s hindi name is Ulatkambal,
and Latin name is Abroma Augusta. It’s also known as Devil’s cotton in English. This plant is full of medicinal
value, especially for gynecological disorders. Such as – Dysmenorrhea, amenorrhea, sterility, anovulation etc.
numerous studies are carried out on its rheumatic pain, headache with sinusitis and in antidiabetic effect. Almost
each and all parts of this plant are used for the treatment of various disorders. This plant belongs to the malvaceae
family and has one or two species from Asia and Africa. Abroma Augusta has been claimed to possess the majority of biological activities. Biochemical profiling of this plant demonstrates the presence of important phytochemicals like alkaloids, abromin, sterol, abromasterol, taroxerylacetate, taraxerol and bita-sitosterol which is very useful in treating uterine disorders.
The aim of this review was to analyze the published report based on the medicinal value of abroma Augusta as
well as to provide updated information about the ethnomedicinal, pharmacological as well as the phytochemical
properties.
SANDHANIYA MAHAKASHAYA: AN OVERVIEW ON PHARMACOLOGICAL
STUDY
Authors: Soni Yashwant , kumar sharma Ashwini
Published: September 2023

The old, conventional medical system known as Ayurveda, which is founded on folklore and ethnopharmacology,
has a wealth of knowledge. One of the well-known treatises of ancient conventional medicine, the Charaka Samhita, has a long history of knowledge. In the fourth chapter, "Shad Virechana Shatashriteeya" of Sutra Sthana in
the Charaka Samhita, Acharya describes 50 Mahakashaya or Dashemani. One such organisation is the Sandhaniya Mahakashaya, often known as Unifying medicine. The word "sandhaniya" literally means "to bind." The term
"sandhan" refers to the connection of two or more objects in a way that avoids the appearance of preparation. Actually, this is what meditation is all about. The word "amalgamation" also means "mixing." A person must also be
able to identify the medication, the way it is used, its beneficial components, etc.
EXPLORING THE EFFECTS OF ALCOHOL INTOXICATION THROUGH THE LENS
OF AYURVEDA AND MODERN SCIENCE.
Authors: A Dahije Amol , Lambat R D
Published: September 2023

Alcohol intoxication is a prevalent problem worldwide, causing numerous health and social issues. While
contemporary medicine provides various treatments and interventions for alcohol-related problems. Ayurveda, the
ancient Indian system of medicine, offers a unique perspective on understanding and addressing alcohol
intoxication. This article aims to explore alcohol intoxication from both Ayurvedic and contemporary viewpoints,
shedding light on their respective approaches, treatments, and overall understanding of this condition.