bluuebunny/crossref_metadata_2025 huggingface dataset:
Верификация расчетной модели для определения связанных деформаций и напряжений плоских элементов из напрягающего бетона
Authors: Санникова О. Г. , Тур В. В.
Published: May 2020

В работе рассмотрены расчетные модели для определения параметров напряженно-деформированного состояния самонапряженных элементов при двухосном ограничении деформаций расширения. Приведены основные положения аналитической модели для определения связанных деформаций и напряжений плоских элементов из напрягающего бетона, базирующейся на модифицированной деформационной модели (MSDM) для случая произвольного линейного ограничения. Выполнена верификация разработанной модели на основании результатов собственных экспериментальных исследований, а также результатов экспериментальных исследований, приведенных в научно-технической литературе.
Analytical Model for Restraint Strains and Self-stressed in Expansive Concrete Filled Steel Tubes (ECFST) estimation
Authors: Tur Viktar V. , Duda Radoslaw , Khmaruk Dina , Basav Viktar
Published: May 2020

In this paper, a modified strains development model (MSDM) for expansive concrete-filled steel tube (ECFST) was formulated and verified on the experimental data, obtained from testing specimens on the expansion stage. The modified strain development model for restraint strains and self-stresses values estimation in concrete with high expansion energy capacity under any type of the symmetrical and unsymmetrical finite stiffness restraint conditions was proposed. Based on proposed MSDM a new model for expansive concrete-filled steel tubes is developed. The main difference between this model and other previously developed models consists in taking into account in the basic equations an induced force in restrain that is considered as an external load
applied to the concrete core of the member. For verification of the proposed model-specific experimental studies were performed.
As follows from comparison results restrained expansion strains values calculated following the proposed model shows good compliance with experimental data. The values predicted by the proposed MSDM for concrete-filled steel and obtained experimental data demonstrated good agreement that confirms the validity of the former.
Upaya Meningkatkan Kemampuan Menulis Cerita Fantasi dengan Menggunakan Metode Picture And Picture Pada Siswa Kelas VII A SMPN 2 Sindangresmi
Authors: Hayati Futri Asri , Supriatna Eman
Published: May 2020

Abstrak. Penelitian Tindakan Kelas dilaksankan dengan tujuan untuk meningkatkan kemampuan siswa dalam menulis teks cerita fantasi dengan menggunakan metode picture and picture dalam pembelajaran. Penelitian dilaksankan di kelas VII A, semester 1, Tahun Pelajaran 2019/2020, SMP Negeri 2 Sindangresmi. Penelitian ini dilatar belakangi rendahnya minat, keaktifan serta kemampuan siswa dalam menulis cerita fantasi. Hal ini terjadi karena ketidak tepatan pemilihan media pembelajaran yang digunakan guru. Media pembelajaran yang digunakan oleh guru kurang bervariasi dan kurang menarik dalam pembelajaran menulis cerita fantasi sehingga siswa merasa bosa.

Masalah yang dikaji dalam penelitian ini adalah (1) Bagaimana penggunaan metode pembelajaran picture and picture dapat meningkatkan minat siswa kelas VII A SMP Negeri 2 Sindangresmi dalam menulis teks cerita fantasi? (2) Bagaimana penggunaan metode pembelajaran picture and picture dapat meningkatkan keaktifan siswa kelas VII A SMP Negeri 2 Sindangresmi dalam menulis teks cerita fantasi? dan (3) Bagaimana meningkatkan kemampuan menulis cerita fantasi dengan menggunakan metode picture and picture  pada siswa kelas VII A SMP Negeri 2 Sindangresmi?

Penelitian Tindakan Kelas dilaksankan 2 siklus yang tiap siklusnya terdiri 4 tahap, yakni perencanaan, pelaksanaan, observasi dan refleksi. Inttrumen yang digunakan dalam penelitian ini berupa lembar tes hasil belajar yang diberikan sebelum tindakan (pratindakan/prasiklus) dan setelah tindakan, lembar observasi serta lembar kerja kelompok. Pengumpulan data dan penggolahannya berdasarkan  data  yang didapatkan pada intrumen tersebut.

Kemampuan menulis cerita fantasi pada siswa kelas VII SMP Negeri 2 Sindangresmi meningkat setelah menggunakan metode picture and picture sebesar 22,77. Rata-rata pada siklus I menunjukan peningkatan dibandingkan dengan rata-rata pada prasiklus 60,23 menjadi 71,5. Rata-rata yang dicapai pada siklus II 83 , ini menujukan peningkatan sebesar 11,27 dari prasiklus ke siklus I, 11,5 dari siklus I ke siklus II. Perubahan aktivitas dan minat siswa dalam pembelajaran menulis cerita fanntasi dengan menggunakan metode picture and picture telah mengalami perubahan kearah yang positif. Hasil penelitian menunjukkan bahwa pembelajaran Bahasa Indonesia kompetensi dasar menulis teks cerita fantasi dengan menggunakan metode picture and picture ternyata dapat meningkatkan keaktifan, minat, dan hasil belajar peserta didik dalam bentuk kemampuan menulis cerita fantasi, dibandingkan dengan kegiatan pembelajaran sebelum melakukan penelitian. Setelah diadakan penelitian tindakan kelas dengan menggunkan metode picture and picture ada peningkatan.
Peningkatan Kualitas Pelayanan Kesehatan dan Pengaruhnya Terhadap Peningkatan Kepuasan Pasien di Puskesmas
Authors: Kosasih Kosasih , Paramarta Vip
Published: May 2020

Melalui penelitian ini diharapkan mendapatkan data bukti empirik tentang peningkatan kualitas pelayanan kesehatan dan pengaruhnya terhadap peningkatan kepuasan pasien dalam rangka mendukung percepatan ekonomi dan pengentasan kemiskinan di Kecamatan Sindangkerta, Kabupaten Bandung Barat. Objek penelitian ini dibatasi pada pasien yang menggunakan BPJS kesehatan.Metode penelitian yang digunakan adalah analisis deskriptif dan verifikatif dengan cara kuantitatif dan analisis regresi linier berganda. Teknik pengumpulan data menggunakan teknik accidental sampling atau teknik incidental sampling, yaitu metode pengambilan sampel dengan memilih pasien yang sudah menyelesaikan perawatan di Puskesmas Cicangkanggirang. Terbukti secara empiris dan hasil penelitian menunjukkan bahwa peningkatan kualitas layanan kesehatan dengan dimensi: Tangible, Empathy, Reliability, Responsiveness, dan Assurance secara simultan mempengaruhi peningkatan kepuasan pasien di Puskesmas Cicangkanggirang di Kecamatan Sindangkerta, Kabupaten Bandung Barat. Hal ini sangat bermanfaat dan membantu bagi pasien yang berobat dari kalangan masyarakat miskin dan kemampuan ekonomi yang rendah.
Peluang Mata Pelajaran Ilmu Pengetahuan Sosial (IPS) dalam Mewujudkan Pendidikan Yang Berbasis Multikultural
Authors: Rahmawati Tri Nurza
Published: May 2020

Absract- This article will explain and describe the opportunities for Social Sciences subjects in realizing multicultural-based education. In compiling this article, the authors used the literature study method is data collection techniques are carried out using books, and other literatures such as journals or articles related to the theme discussed. The results showed that multicultural-based education is education that must be realized in formal education in Indonesia, departing from the conditions of people in Indonesia who have a diversity of ethnicities, cultures, and religions. Seeing all subjects in the world of education at the junior high level, Social Sciences subjects have a very strategic position. This is based on aspects of the study in the subject of Social Sciences providing a gap in almost every material. Thus, the availability of the gap is expected to be used as fully as possible and as effectively as possible in incorporating multicultural values, for the creation of multicultural-based education.

 

Keyword: Social Sciences, Education, Multicultural

 

Abstrak- Artikel ini akan menjelaskan dan mendeskripsikan Peluang mata pelajaran Ilmu Pengetahuan Sosial (IPS) dalam mewujudkan pendidikan yang berbasis multikultural. Dalam menyusun artikel ini, penulis menggunakan metode studi pustaka yaitu teknik pengumpulan data dilakukan dengan menggunakan buku-buku, dan literatur-literatur lainnya seperti jurnal ataupun artikel yang terkait dengan tema yang dibahas. Hasil penelitian menunjukkan bahwa pendidikan berbasis multikultural merupakan pendidikan yang harus diwujudkan dalam pendidikan formal di Indonesia, berangkat dari kondisi masyarakat di Indonesia yang memiliki keragaman suku bangsa, budaya, dan agama. Melihat semua mata pelajaran dalam dunia pendidikan ditingkat SMP, mata pelajaran Ilmu Pengetahuan Sosial memiliki kedudukan yang sangat strategis. Hal ini didasari aspek kajian dalam mata pelajaran Ilmu Pengetahuan Sosial menyediakan celah hampir disetiap materi. Dengan demikian, ketersediaan celah tersebut diharapakan mampu digunakan semaksimal mungkin dan seefektif mungkin dalam memasukkan nilai-nilai multikultural, guna terciptanya pendidikan yang berbasis multikultural.

 

Kata Kunci: Ilmu Pengetahuan Sosial, Pendidikan, Multikultural
Digital et évolution des mobilités spatiales
Authors: DELAUNAY Anne-Laure
Published: May 2020

Le manager intermédiaire sur site de production gère des équipes dispersées sur un périmètre délimité. Entre éloignement et proximité, entre visibilité et invisibilité, il doit quotidiennement gérer les spécificités de sa mobilité spatiale. Nous pensons notamment aux managers de site tels que les établissements de santé (production de soin), les usines (production industrielle) où les membres de l'équipe sont présents mais répartis physiquement sur site entre les étages et les bâtiments. En quoi l'usage des technologies digitales participe-t-il à l'évolution des mobilités spatiales de ces managers ? A partir d'une ethnographie de vingt-sept mois au sein d'un grand groupe industriel français et de trois de ses usines, nous apportons un éclairage sur la mobilité spatiale des managers intermédiaires sur site de production, entre mobilité réelle et virtuelle et entre semi-sédentarité et semi-nomadisme.
A Rapid Method for the Retrieval of Bioactive Xanthone from Garcinia Mangostana: A Case Study of α-Mangostin
Authors: Khaw Kooi Yeong , Ong Yong Sze , Goh Bey-Hing
Published: May 2020

Natural products have been used as the functional food and alternative treatment to combat various diseases for centuries. A handful of bioactive compounds that are available clinically such as antibiotic, anti-neurodegeneration, and anticancer drugs were derived from natural products. Recent study showed that α-mangostin, a natural occurring prenylated xanthone, possesses a wide variety of pharmacological activities including anti-cancer, anti-inflammation, anti-bacterial, anti-viral, and anti-neurodegenerative. In view of the pharmacological importance of α-mangostin, a rapid extraction method is paramount importance to recover the α-mangostin from natural resources to cope the therapeutic needs and potential for future clinical translation. The yield of α-mangostin was 9.2 g/kg DW. This study presents a simple, cost effective, and rapid extraction with identification of α-mangostin from the pericarp of the mangosteen fruit.
Comprehensive Insight of Neurodegenerative Diseases and The Role of Neurotoxin Agents — Glutamate
Authors: Yap Hui-Min , Lye Kwan-Liang , Tan Loh Teng-Hern
Published: May 2020

The increased concentration of extracellular glutamate has been reported to play a key role in most of the neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease, even though its importance as an amino acid neurotransmitter in mammalian. Glutamate toxicity, which can be caused by excessive intake of monosodium glutamate (MSG), is the major contributor to pathological neuronal cell death. It causes neuronal dysfunction and degeneration in the central nervous system (CNS). Glutamate neurotoxicity can be categorized into two forms, which are receptor-mediated glutamate excitotoxicity and non-receptor mediated glutamate oxidative toxicity. The receptor-mediated glutamate excitotoxicity involved excessive stimulation of glutamate receptors (GluRs) which lead to excessive ion calcium (Ca2+) influx and activates a cell death cascade involving the accumulation of mitochondrially generated reactive oxygen species (ROS). Studies showed excessive extracellular glutamate leads to nerve cell death via the activation of N-methyl-Daspartate (NMDA) receptors in the cases of trauma or stroke. Whereas non-receptor mediated oxidative toxicity involved the breakdown of the cystine/glutamate antiporter (xc - ) mechanism, which leads to the depletion of glutathione (GSH) and causes oxidative stress and cell death. The cystine/glutamate antiporter couples the import of cystine to the export of glutamate. The increased concentration of extracellular glutamate could inhibit the uptake of cystine, which is required for the synthesis of the intracellular antioxidant GSH. GSH plays an important role in the disposal of peroxides by brain cells and in the protection against ROS. Depletion of GSH renders the cell to oxidative stress and ultimately leading to cell death. This article aims to provide a comprehensive review of neurodegenerative diseases and the role of neurotoxin agents, glutamate in these diseases.
A Typology of Rural Space in Czechia according to its Potential for Development
Authors: Perlín Radim , Kučerová Silvie , Kučera Zdeněk
Published: May 2020

The objective of this article is the regional differentiation of rural space in Czechia, which is defined as the territory of rural municipalities of up to 3,000 inhabitants. The ultimate determination of particular types of rural space is realized at the level of authorized municipal authorities. Current socioeconomic characteristics of rural municipalities in Czechia are compiled and used for analysis. These characteristics were selected on the basis of their potential to represent important socioeconomic phenomena, processes and factors that are typical for the Czech countryside and that influence the development of rural municipalities. Four statistically significant components are identified through the statistical analysis of the indicated data at the level of authorized municipal authorities, namely:size,growth,human potentialandhousing. Different combinations of these components enable us to define eight main types of rural space, in terms of potential for development. This provides evidence to confirm our affirmation that rural space in Czechia is not homogenous. The results of the statistical analyses conducted also show that the basic differentiation of the Czech countryside is determined by the geographical location of particular areas.
PENGARUH RANGE OF MOTION TERHADAP KEKUATAN OTOT PADA PASIEN STROKE ISKEMIK DI RUMAH SAKIT UMUM HKBP BALIGE
Authors: Hutahaean Rika Elvriede , Daniel Hasibuan Muhammad Taufik
Published: May 2020

Ischemic stroke is a disruption of blood supply to the brain which results in stoppage of blood flow and blood clots that cause atherosclerosis. Ischemic stroke patients can be given training or therapy to help maintain or increase muscle strength with range of motion. Range of motion is usually given during the recovery period or when the patient's condition has improved with a frequency of twice a day in 10-15 minutes. This study aims to determine the effect of range of motion on muscle strength in Balige HKBP General Hospital. This type of research uses one group pretest-posttest and the sample used in this study amounted to 30 people, and the total sampling used in sampling techniques in the population. Data collection was carried out by questionnaire, observation and interview as well as data testing which was carried out using the Wilcoxon test. From the test results obtained a significant effect of 0,000. That is, there are differences in muscle strength before and after given the range of Motion. This proves that Range of Motion affects the increase in respondent's limb muscle strength. The hospital is expected to make an SPO in the handling of rehabilitation of ischemic stroke patients to maintain and increase muscle strength.

 

 

Abstrak

Penyakit stroke iskemik merupakan terganggunya pasokan darah ke otak yang mengakibatkan berhentinya aliran darah dan terjadi pembekuan darah sehingga menyebabkan aterosklerosis. Pasien stroke iskemik dapat diberikan latihan atau terapi untuk membantu mempertahankan atau meningkatkan kekuatan otot yaitu dengan range of motion. Range of motion biasanya diberikan pada masa pemulihan atau pada saat kondisi pasien sudah membaik dengan frekuensi dua kali sehari dalam waktu 10-15 menit. Penelitian ini bertujuan untuk mengetahui adanya pengaruh range of motion terhadap kekuatan otot di RSU HKBP Balige. Jenis penelitian ini menggunakan one group  pretest-postest dan sampel yang dipakai dalam penelitian ini berjumlah 30 orang, serta total sampling dipakai dalam teknik pengambilan sampel pada populasi. Pengumpulan data dilakukan dengan kusioner, observasi dan wawancara serta uji data yag dilakukan dengan uji Wilcoxon. Dari hasil uji didapatkan pengaruh yang signifikan sebesar 0.000.  Artinya, terdapat perbedaan kekuatan otot sebelum dan sesudah diberikan range of Motion. Hal ini membuktikan bahwa Range of Motion berpengaruh pada peningkatan kekuatan otot ekstremitas responden. Rumah Sakit diharapkan membuat suatu SPO dalam penanganan rehabilitasi pasien stroke iskemik untuk mempertahankan dan meningkatkan kekuatan otot.
Ângulo de fase padronizado e sua relação com parâmetros antropométricos e inflamatórios em mulheres com lúpus
eritematoso sistêmico
Authors: Sales Ana Lina de Carvalho Cunha , de Oliveira Elieide Soares , Primo Maísa Guimarães Silva , Silva Thamara Martins , Mendes Islanne Leal , Rodrigues Gilmara Péres , Martins Maria do Carmo de Carvalho e
Published: May 2020

Introduction: The phase angle is associated with changes in nutritional status and could be
used for nutritional diagnosis, as well as prognostic indicator or survival predictor in some
clinical situations. The aim of this study was to associate the standardized phase angle (AFP) to
anthropometric and inflammatory parameters in women with systemic lupus erythematosus (SLE).
Methods: A cross-sectional study conducted with 23 women diagnosed with SLE. Weight (kg) and
height (m) were evaluated to determine body mass index (BMI), and waist circumference (WC)
was measured according to current standards. Erythrocyte sedimentation (ESR) and C-reactive
protein (CRP) values were obtained from medical records. AFP was obtained by Direct Segmental
Multi-Frequency Electrical Bioimpedance, Inbody S-10, and the value obtained by the standard
deviation was corrected according to age and gender. Statistical analysis included Shapiro-Wilk’s
analysis for symmetry of data distribution and the application of appropriate correlation tests to the
types of variables evaluated, considering significant values of p <0.05. Results: The mean age of
the patients was 34.5 ± 11.4 years, with a mean BMI (27.7 ± 3.7 kg/m²) compatible with excess
body weight. The WC mean (88.5 ± 10.8 cm) indicates abdominal adiposity and high cardiometabolic risk. On average, women’s AFP (-1.23 ± 0.7) indicates nutritional risk, characterized by
less muscle mass and a higher % of body fat (36%). High ESR and CRP values were also found in
the study population. No correlation was found between AFP, anthropometric and inflammatory
parameters in the women evaluated (p> 0.05). Conclusion: Women with SLE are at nutritional
risk, as indicated by AFP, unrelated to the anthropometric and inflammatory parameters evaluated.
Características de pacientes superobesos atendidos em serviço de referência em cirurgia bariátrica
Authors: de Araújo Francisca Luzia Soares Macieira , Batista Edith Monielyck Mendonça , de Araújo Gutemberg Fernandes , Costa Silvana Maria Mendes , Santiago Andréa Karine de Araújo , Gonçalves Ana Cláudia Ribeiro
Published: May 2020

Introduction: Obesity is a worldwide epidemic and people with super obesity (BMI > 50 kg/m²) have the worse prognosis, related to physical complications but also to mental illnesses, physical and verbal abuse, as well as social exclusion. Objective: To determine the profile of super obese patients treated in a referential bariatric surgery service. Methods: Retrospective analysis of 56 medical records of patients treated at the HUUFMA’s Bariatric and Metabolic Surgery Service multidisciplinary ambulatory care in 2017-2019. Incomplete records or with body mass index (BMI) < 50 kg/m² were excluded. Results are presented in mean and standard deviation. Chi-square test
was used for association analysis, Shapiro-Wilks test for normality and significance was considered for p<0.05. Results: Prevalence in sample of females (80.3%), brown skin (67.8%), average age of 37.8 ± 9.8 years, and 49.1% graduated high school. The average weight and BMI were that of 136.6 ± 12.4 kg and 59 ± 6.5 kg/m², respectively, with a patient standing out with a BMI of 71 kg/m². Among the comorbidities we found obstructive sleep apnea in 100%, insomnia in 98.2%, joint problems in 53.5%, anxiety in 50%, hepatic steatosis and systemic arterial hypertension with 48.2% each, dyslipidemia in 42.8%, intestinal constipation in 32.1% and type 2 diabetes mellitus
in 17.8%. There was a significant relation (p<0.05) between schooling and weight. An impact on mental health was observed, with 37.5% of the patients exhibiting depression, 44.6% binge eating and 17.6% suicidal thoughts and/or self-mutilation. Conclusion: The super obese patients’ profile is that of a young adult woman, with average schooling, various comorbidities and with significant impact on mental health.
Parecer da BRASPEN sobre prescrição de volume, consistência e suplemento nutricional no paciente disfágico
Authors: Alvite Maria de Fátima Lago , Piovacari Silvia Maria Fraga , Dock-Nascimento Diana Borges
Published: May 2020

“Dispõe sobre prescrição de consistência alimentar, volume e suplemento nutricional no que diz respeito à atuação do Fonoaudiólogo e atuação do Nutricionista ao paciente disfágico”
Various surgical techniques influence on the local immunity state in the postoperative period in children's tonsils hypertrophy
Authors: Bredun Alexander , Melnikov Oleg , Kosakovsky Anatoly , Shuklina Julia , Timchenko Мarina
Published: May 2020

Topicality: There are many conflicting opinions in the literature regarding the best surgical technique for the treatment of OSAS related to palatine hypertrophy – partial (tonsillotomy) or complete (tonsillectomy) removal of lymphoid tissue of the tonsils. Also, there are many opinions about the use of a variety of traditional and modern surgical instruments to reduce the volume of the tonsils, including using a laser, a radiofrequency knife, an ultrasonic knife, a shaver (microdebrider) and a coblator.
Aim of the study: The aim of the study was to compare the surgical methods effectiveness of tonsils hypertrophy treatment which the based on the restoration of the mucous membrane's local immunity function.
Materials and methods: Children who undergoing surgical treatment for palatine tonsils hypertrophy 2-3 degrees according to the Brodsky classification and the presence of OSAS took part in the study. The patients were randomized and divided into four comparison groups using different surgical techniques. The first group, which used the surgical technique of classical tonsillotomy (TT) included 28 patients, the second group, which used the surgical technique of intracapsular shavertonsillotomy(STT) included 18 patients, the third group, which used surgical technique of intracapsular coblationtonsillotomy (CTT), and groups which using surgical technique of tonsilloplasty included 12 patients (TP). Determined the state of local immunity before surgery and 1 month
after surgery by concentration levels of sIgA, α-IFN, IL-1β, TGF-1β and general-purpose immune complexes.
Results: Recovery of the concentration of the major marker of local immunity sIgA occurs significantly (P<0.05) faster when using the surgical technique of CTT and STT. Recovery of the concentration of the major marker of antiviral immunity α-IFN occurs significantly (P <0.05) faster when using the surgical technique of CTT, STT and TP. Recovery of the concentration of the anti-inflammatory cytokine IL-1β occurs significantly (P<0.05) faster with the use of the surgical technique of STT and TP. Indicators of the regeneration factor TGF-1β are significantly the highest when using the surgical techniques of STT, TT and TP. The concentration of immune complexes in the oropharyngeal secretions of patients with tonsil hypertrophy at 1 month after surgery significantly decreased with the use of surgical techniques TT and TP. Significant (P <0.05) increase in IgG level was de-
termined in all comparison groups except the group where tonsilloplasty was used.
Conclusions: The safety surgical technique of palatine tonsils volume reduction – TP and STT promotes significantly (P<0,05) faster restoration of concentration of the main mucous membrane's local immunity markers.
Nasal endoscopy prospectsin experimental rhinology: some aspects of enisamium iodide nasal spray effectiveness in rhinosinusitis
Authors: Zhulai Tetiana , Zupanets Igor , Shebeko Sergii , Yampolska Kateryna
Published: May 2020

Acute rhinosinusitis treatment and prevention is connected to the rational choice of drug dosage form, which will provide the therapeutic effect and the safety of a drug substance or a drug substance complex. Nasal spray with Enisamium Iodide can be used to nasal congestion relief in acute rhinosinusitis because the active substance has an anti-exudative action. Nasal endoscopy could be used in experimental rhinology as a method for direct pathology visualization and for evaluation of the effectiveness of test drugs.
Aim: To substantiate Enisamium Iodide (nasal spray) 10 mg/mL effectiveness on maxillary sinus ostium via nasal endoscopy in rabbits with experimental rhinosinusitis.
Methods: As a test object was used Enisamium Iodide (nasal spray). As a reference drug, we used BNO-101. Experimental rhinosinusitis was induced in the 1st day. On the 1st , 15th and 25th days in all groups (four groups, six rabbits in each group), we used nasal endoscopy and semi-quantitative assessment to the result objectivity.
Results: The total score in the intact control group was 0 (0÷0) on the 15th and 25th days (physiological state). The total score in the control pathology group was 2.0 (2.0÷2.0) and 2.0 (1.0÷2.0) (severe rhinosinusitis) respectively. The total score in Enisamium Iodide treated group was 2.0 (1.0÷2.0) (severe rhinosinusitis) and 0.0 (0.0÷1.0) (physiological state). The total score in BNO-101 treated group was 2.0 (1.0÷2.0) (severe rhinosinusitis) and 1.0 (1.0÷1.0) (mild rhinosinusitis).
Conclusions: Nasal endoscopy can be used as an informative visual method. Enisamium Iodide (nasal spray) has been shown a positive effect by endoscopic evaluation of maxillary sinus ostium and exceeded activity of the reference drug.
Survival of patients with resectable advanced oral cancer of different subsites
Authors: Kravets Oleg , Cherniienko Viktor
Published: May 2020

Objective: The aim of the study was to analyze the differences in survival of patients with resectable oral squamous cell carcinoma at stages III-IV of different oral cavity subsites and the impact of clinical and pathological factors on the prognosis of the disease.
Mаterials and methods: 295 patients with resectable oral squamous cell carcinoma at stages III-IV.
Results: Comparing the overall and free survival curves, no statistically significant difference between the different subsites was established (p=0.55 and p=0.77, respectively, according to the logrank test). Independent prognostic impact on overall and free survival of the disease stage was revealed during multivariate analysis (HR=3,44 (95% CI 2,33-5,06; p<0,001) and HR=3,57 (95% CI 2,42–5,28; p<0,001); presence of surgical complications (HR=2,50 (95% CI 1,76–3,56; p<0,001) and HR=2,46 (95% CI 1,73-3,50; p<0,001) respectively); positive resection margin HR=4,00 (95% CI 2,36-6,78; p<0,001) and HR=3,87 (95% CI 2,29-6,56; p<0,001) respectively); extracapsular extension (HR=2,57 (95% CI 1,75-3,79; p<0,001) and HR=2,43 (95% CI 1,65-3,58; p<0,001) respectively); multiple lymph node involvement (HR=2,41 (95% CI 1,63-3,55; p<0,001) and HR=2,53 (95% CI 1,71-3,73); high histopathological grade (HR=1,48 (95% CI 1,10-1,98; p=0,009) and HR=1,58 (95% CI 1,18-2,12; p=0,003) respectively).
Conclusion: The study found no statistically significant differences between overall survival and diseasefree survival in patients with advanced resectable oral squamous cell carcinoma of different oral subsites. The independent clinical prognostic factors of poor prognosis in patients with locally advanced resectable oral squamous cell carcinoma were stage IV and the presence of surgical complications. Independent pathological factors were: positive surgical margin, extracapsular nodal extension, multiple lymph node involvement and histopathological grade.
PENINGKATAN HASIL BELAJAR PASSING BAWAH PADA PERMAINAN BOLA VOLI MELALUI PEMBELAJARAN MEDIA TEMBOK PADA SISWA KELAS VIII SMP NEGERI 13 MAKASSAR
Authors: Suhardianto
Published: May 2020

Penelitian ini bertujuan untuk mendeskripsikan perencanaan, pelaksanaan, observasi, refleksi dan penerapan media tembok dalam upaya meningkatkan hasil belajar passing bawah pada permainan bola voli pada siswa kelas VIII SMP Negeri 13 Makassar. Penelitian ini merupakan Penelitian Tindakan Kelas (PTK) yang terdiri dari dua siklus, pada tiap siklus terdapat empat tahapan yaitu perencanaan, pelaksanaan, observasi dan refleksi. Data penelitian ini adalh kemampuan passing bawah sebagai data psikomotor dan nilai soal latihan sebagai nilai kognitif serta pengamatan sebagai nilai afektif.  Subjek penelitian ini adalah siswa kelas VIII SMP Negeri 13 Makassar, sebanyak 29 siswa. dengan rincian siswa 13 siswa Laki-laki dan 16 siswa perempuan. Berdasarkan hasil analisis kuantitatif data hasil belajar passing bawah menujukkan bahwa siswa yang tuntas pada siklus I adalah 13 orang denga persentase 45 % sedangkan jumlah siswa yang tuntas pada siklus II adalah 29 orang dengan persentase 100%. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa pembelajan passing bawah melalui media tembok  dapat meningkatkan hasil belajar passing bawah pada permainan bola voli SMP Negeri 13 Makassar
The Efficiency of GARCH Models in Realizing Value at Risk Estimates
Authors: Jeřábek Tomáš
Published: May 2020

Market risk is an important type of financial risk that is usually caused by price fluctuations in financial markets. One determinant of market risk comprises Value at Risk (VaR), which is defined as the maximum loss that can be achieved within a certain time horizon and at a given reliability level. The aim of the article is to determine the importance of selecting conditional volatility model within the parametric and semi-parametric approach for VaR estimation. The results ascertained show that the application of these models tends to provide more accurate predictions of actual losses as compared to traditional approaches to VaR estimates. Overall, the application of conditional volatility models ensures that VaR estimates are more flexible to adapt to changing market conditions – especially in the periods associated with higher return volatility. Furthermore, the results show that the differences between individual models of contingent volatility are primarily determined by selecting the specific distribution of the standardized residue series
The Effect of Dehulling Lupine Seeds (Lupinus albus L.) from Low-Alkaloid Varieties on the Chemical Composition and Fatty Acids Content
Authors: Struti Danut Ioan , Mierlita Daniel , Simeanu Daniel , Pop Ioan Mircea , Socol Claudia Terezia , Papuc Tudor , Macri Adrian Maximilian
Published: May 2020

The aim of this study was to analyze the effect of dehulling white lupine seeds (Lupinus albus, cultivar Amiga) on the raw chemical composition and nutritional profile of lipids. There was no significant differences (p ˃ 0.05) between whole and dehulled lupine seeds in respect of their content in dry matter, ether extract, crude ash and nitrogen-free extract. However, the dehulled lupine seeds had a higher (p ˂ 0.05) crude protein level (51.69% of DM) than whole seeds (43.16% of DM), and a lower (p ˂ 0.05) crude fiber content (4.35% of DM) compared to that of whole seeds (14.15% of DM). The fatty acids profile is not affected (p ˃ 0.05) by the dehulling process. Oleic acid (C18:1 cis-9) is the main fatty acid in lupine seeds, and the level of monounsaturated fatty acids (MUFA) is slightly higher in whole seeds. The n-3 / n-6 report is adequate in both whole (0.88) and dehulled (0.94) seeds, and the favorable polyunsaturated index (PI) indicates the high content of polyunsaturated fatty acids (PUFA), which indicates that lupine seeds are a valuable source of essential fatty acids. Also, lupine seeds are characterized by favorable values of the thrombogenic (0.18) and atherogenic (0.14) indexes, and an appropriate hypocholesterolemic/hypercholesterolemic index value, features considered important for human health and animal nutrition.
Antioxidant Silver-based Biogenic Systems Generated from Arctium lappa Leaves
Authors: Barbinta-Patrascu Marcela Elisabeta , Besliu Daniela , Meghea Aurelia
Published: May 2020

This work aims at designing through a �green� bottom-up strategy, four types of bio-based systems containing artificial cell membranes (with or without vitamin C) and silver nanoparticles (AgNPs) phyto-generated from aqueous extract of Arctium lappa leaves. The �green� approaches for AgNP synthesis, by using the vast bioreducing potential of plants are low-cost and eco-friendly procedures.Exploiting vegetal wastes as precursors for phyto-metallic nanoparticles has received attention from scientific community in the last years due to its significant economic and environmental impacts. UV-Vis absorption spectra demonstrated the biosynthesis of metallic nanoparticles which exhibited a strong SPR peak located at 437 nm wavelengths. The formation of the biocomposites containing the �green� synthesized AgNPs has been demonstrated by UV-Vis absorption spectroscopy and Dynamic Light Scattering measurements. DLS results highlighted the nanoscale size of the prepared �green� AgNPs. The physical stability of the obtained silver-based systems was evaluated through zeta potential values, based on electrophoretic mobility. The systems loaded with vitamin C proved to be more stable and showed enhanced antioxidant activities (between 72.3% to 88% evaluated by chemiluminescence technique). Our results demonstrated that these developed silver-based biogenic systems generated from Arctium lappa leaves could be used as antioxidant agents in various biomedical applications.
Impacts of Using Mineral Fertilization Combined with Sewage Sludge in the Amendment of Luvisol on Oat Crop I. Influence on Yield and Mineral Nutrition
Authors: Ilie Leonard , Mihalache Mircea , Madjar Roxana Maria , Calin Catalina , Scaeteanu Gina Vasile
Published: May 2020

The present paper illustrates the results obtained on oat (Avena sativa L.), Somesan variety, concerning growth, grains and straw yields and also of macroelements accumulation (N, P, K, Ca, Mg) when various doses of sewage sludge were applied associated or not with mineral fertilization. Sewage sludge application produced significant increase of plant height starting with equivalent dose of 100 kg N/ha, meanwhile the highest height was observed in the case of plants fertilized with doses equivalent with 300 and 400 kg N/ha. With the increase of sewage sludge dose it has been observed the straw yield increase, this being statistically assured starting with sewage sludge equivalent dose of 100 kg N/ha. Sewage sludge fertilization, accompanied or not by mineral fertilizers, evidenced that nitrogen contents in oat grains increases with applied sewage dose, being significant from an equivalent dose of 200 kg N/ha. Low sewage doses equivalent with 200-300 kg K/ha evidenced for potassium concentration in oat grains a significant decrease in comparison with untreated variant, meanwhile mineral fertilization generated a significant increase of potassium levels in oat grains. Calcium contents in oat grains present a significant increase after sewage sludge fertilization and at a dose equivalent with 600 kg N/ha, the calcium levels (0.24%) increased 3 times in comparison with untreated variant (0.08%). Sewage sludge fertilization, associated or not with mineral fertilizers, did not produced significant changes of magnesium levels in oat grains, found concentrations being considered as normal values.
Analysis of Volatile Organic Compounds from the Aerial Parts of Medicinal Plant, Galium verum
Authors: Ciotlaus Irina , Pojar-Fenesan Maria , Balea Ana
Published: May 2020

The Galium verum herb, (Rubiaceae family) is well represented in the spontaneous Romanian flora. She is one of the most used plants in traditional medicine. Our research aimed to investigate the chemical volatile profile in fresh, dried and essential oil of Gallium verum using SPME and hydrodistillation techniques, followed by GC-MS analysis. Characterization of volatile compounds composition by SPME �GC-MS technique presented din this paper is the first study on fresh and dried of Galium verum plant to our knowledge. Galium verum fresh flower floral bouquet is given by monoterpenes (73,5%), sesquiterpenes (10,16%), esters (10,26%) and others(5.87%). The floral bouquet of Gallium verum dried flower, contains mainly: aldehydes (35.48%) monoterpenes (35.48%), alcohols (11.96%), sesquiterpenes, (3.71%), esters (3.14%) and others (10.11%). Sixty components were identified in the galium essential oil.
Optimization by Experimental Design of Copper Adsorption on Natural Clay
Authors: Stanasel Oana Delia , Bota Sanda Rodica , Stanasel Iulian , Blidar Cristian Felix , Serban Georgeta
Published: May 2020

Natural clay from the Felix geothermal area was used to assess the possible removal of heavy metals from wastewaters. Several experimental conditions, including pH, contact time and temperature, depending on the initial concentration were studied. The design of experiments method was applied in order to get the highest percentage of adsorbed copper. The factorial experiments were performed according to the matrix program developed by Design Expert. The obtained mathematical model assessed the optimal values of the factors that influence the adsorption of copper, taking into account maximum productivity, as well as economic criteria. The estimated values were in accordance with the experimental research.
The Improvement of Degradation Strength of aAlkyd Resin EZ 528 Used in Rotating Machines
Authors: Zaharescu Traian , Lungulescu Eduard-Marius , Dumitru Alina , Marinescu Virgil
Published: May 2020

The addition of inorganic phase consisting of Ce-doped PbZrO3, a promising solution to increase the thermal and radiation strengths of electroinsulating alkyd resin EZ 528 used in rotating machines is studied. The delay of oxidation of filler is based on the electronic interaction between the former degradation intermediates and lattice defects.
A Comparative Study on the Adsorption of Two Remazol Dyes on Green Adsorbent
Authors: Rapo Eszter , Jakab Krisztina , Posta Katalin , Suciu Maria , Tonk Szende
Published: May 2020

Due to the large amount of wastewater discharged by the textile industry, many alternative researches have been undertaken in recent years to effectively remove textile dyes from water. In our study, the adsorption from aqueous solution of two important textile dyes, reactive azo dyes Remazol Red (RR) and Remazol Blue (RB) was studied with calcined chicken eggshell (Gallus Gallus domesticus) adsorbent. Batch biosorption studies were conducted to evaluate the effect of various parameters, such as contact time, initial dye concentration, amount of adsorbent, and pH, to determine the optimal adsorption parameters (Remazol Brilliant Red F3B: Ci=20 mg/l, 1.5g adsorbent, 160 μm, 700 rpm, pH=6.0�0.2, T=20�2 oC, where E%=97.3; Remazol Brilliant Blue R: Ci=20 mg/l, 1.5 g adsorbent, 160 μm, 700 rpm, pH=6.0�0.2, T=20�2oC, where E%=98.8). The changes in morphological structure were evaluated by SEM analysis. The experimental isotherm data were analyzed using the Langmuir, Freundlich, Dubinin-Radushkevich and Temkin isotherm models. Biosorption kinetics data were tested using pseudo-first-order, pseudo-second-order, where in our experimental conditions the biosorption followed a pseudo-second-order reaction. EDS analyses were carried out, and bioconcentration factors were calculated before and after adsorption. The results of this study indicate that adsorption with calcined eggshell is a promising, feasible, reliable and eco-friendly method for Remazol textile dye removal from aqueous solutions.
Carotenoids, Flavonoids, Total Phenolic Compounds Content and Antioxidant Activity of Indigenous Pyracantha coccinea M. Roem. Fruits
Authors: Popoviciu Dan Razvan , Negreanu-Pirjol Ticuta , Motelica Ludmila , Negreanu-Pirjol Bogdan-Stefan
Published: May 2020

Scarlet/red firethorn, Pyracantha coccinea M. Roem., is a common ornamental shrub, commonly cultivated nowadays in Romania and many other countries, in gardens or hedges. The tree has small white flowers and it produces small bright colored berries. The fruit is bitter and astringent, making it inedible when raw. The fruit can be cooked to make jellies, jams, sauces and marmalade. In this study, the Pyracantha coccinea M. Roem fruits from three common cultivars named �Orange Glow�, �Red Column� and �Soleil d�Or�, were collected from different individuals in Constanta city, Romania. Both frozen and dried (80�C) fruits were analyzed for the active principles content such as, carotenoids, flavonoids and total phenolic compounds correlated with antioxidant activity. Carotenoids were determined by acetone extraction and UV-Vis spectrophotometry, flavonoids, by methanol extraction and UV-Vis spectrophotometry and total phenolic, by methanol extraction, Folin-Ciocalteu reaction and UV-Vis spectrophotometry. The total antioxidant capacity was quantified through photochemiluminescence method by comparison with the standard substance used for calibration, Trolox� as tocopherol analogue (ACL procedure) using Photochem apparatus, Analytik Jena AG, Germany. The average carotenoid content in fresh frozen fruits ranged between 278-545 mg/kg (dry weight equivalent), while in dry material 133-203 mg/kg. Total flavonoids averaged 1415-4953 mg/kg in fresh fruits, increasing after heat-drying to 2981-5759 mg/kg. Fresh fruits contained a total amount of phenolic compounds of 11501-21107 mg/kg DW gallic acid equivalent, while dry fruits averaged 5749-8261 mg/kg GAE. Pyracantha coccinea M. Roem. fruits emphasized an increased antioxidant activity correlated with a high content of potentially bioactive compounds, especially of phenolic compounds, both in frozen and heat-dried state. �Red Column� and �Orange Glow� are the most promising varieties of the three cultivars, for potential pharmaceutical applications.
The Romanian Map of Organic Pollution from Domestic Wastewaters � Seasonal Variations of Anionic Surfactants And Organic Load (COD)
Authors: Mitru Daniel , Nechifor Gheorghe , Gheorghe Stefania , Paun Iuliana , Ionescu Lucian , Nita-Lazar Mihai , Lucaciu Irina Eugenia
Published: May 2020

Surfactants represent the major class of chemicals used in the composition of detergents where the predominant groups are anionic surfactants. Because of the large utilization of detergents in different activities (agricultural, industrial, domestic) an important amount of surfactants can accumulate in the domestic and industrial wastewaters, that are discarded to wastewater-treatment plants (WWTP). Furthermore, surfactants could affect the process of biological wastewater treatment due the inhibition of activated sludge and subsequently the water bodies quality through discharge of WWTPs` effluents. In addition, the soil quality decreased through various modes of sludge applied. The concentrations of organic matters discharged in the wastewater systems from Romania have raised the attention of environmental authorities regarding the toxic impact of their components such as anionic surfactants on the environment. The present paper proposed to highlight the background of organic pollution from Romania through the monitoring of the organics amount in water by Chemical Oxygen Demand (COD) and by the specific indicator � Anionic Surfactants (AS). Temporal (winter, spring and summer, 2019) and spatial (six areas: West, North-West, North-East, East, South and South-West) monitoring of organic matter was performed. It has been found that the spatial and temporal variation of AS concentrations were well correlated with COD load, leading to the conclusion that surfactants represented an important part of the global organic matter.
Coordination Compounds of Platinum and Palladium with Mixed Ligands (Usnic Acid and 1-(o-Tolyl) Biguanide) � Synthesis, Spectral Characterization and Biological Activity
Authors: Calinescu Mirela , Oprea Ovidiu , Stoica Catalina , Nita-Lazar Mihai , Mihalache Madalina
Published: May 2020

Four coordination compounds of Pd(II), Pt(II) and Pt(IV) with usnic acid (H3AU) and 1-(o-tolyl)biguanide (TB) as ligands have been synthesized in view of their potential as antimicrobial, antifungal and antitumor agents. The metal complexes have been characterized by elemental and thermogravimetrical analyses, infrared and electronic spectra. Based on these studies, the following formulas have been proposed for the complexes: [Pd(TB)(H3AU)]PdCl4 (C1), [Pd(TB)(H2AU)] CH3COO (C2), [Pt(TB)(H2AU)Cl2]Cl (C3) and [Pt(TB)(H2AU)]Cl (C4), where H2AU is deprotonated usnic acid. The in vitro biological activities of the new complexes were tested against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Candida albicans ATCC 10231 and HeLa tumor cells. All complexes were found to have good biological properties and therefore they can be further explored in therapeutic applications.
Assessment of Zinc and Nickel Profile of Vegetables Grown in Soil Irrigated with Sewage Water
Authors: Liang Hao , Khan Zafar Iqbal , Ahmad Kafeel , Nisar Anam , Mahmood Qaisar , Ebadi Abdol Ghaffar , Toughani Mohsen
Published: May 2020

The current investigation assessed the nickel and zinc contents of the soil, and the vegetables grown in wastewater irrigated areas. Atomic Absorption Spectrophotometer (AA-6300 Shimadzu Japan) assessed the metal profile of the samples. The mean concentrations of metals in soil samples varied from O.O85 to 1.611 mg/kg for Ni and O.453 ~ O.9O8 mg/kg for Zn. In vegetables, the maximum Ni concentration was observed in Capsicum baccatum consequent to wastewater irrigation, while its minimum concentrations were noticed in Capsicum frutescens after canal water irrigation. Sewage water irrigation resulted in the highest Zn contents in Solanum lycopersicum and the lowest Zn contents were noticed in Capsicum baccatum after canal water irrigation. The daily intake values of Ni and Zn were higher caused by sewage water irrigation as compared to the canal water irrigation in all tested vegetable samples. Health risk index (HRI) values for Ni and Zn accumulation in vegetables fell within the permissible limit in Pakistan and these were regarded as appropriate for human intake.
Study on Soil Heavy Metal Content and Ecological Risk Assessment of Jiaozhou Bay of China
Authors: Sen Liu , Nan Gao , Lee Han-Seok , Li-Meilun Zhu , Heng Li , Jie Yang
Published: May 2020

Sampling and analyzing the soil of coastal public green space in Jiaozhou Bay, Qingdao, a total of 31 plots were surveyed, 242 soil samples were collected, and the types and contents of heavy metals in the soil were analyzed. The ecological risk index method and the ground accumulation index method were used to evaluate Qingdao Jiaozhou Bay. Heavy metal risk in coastal public green space. The results show that the average content of Cr, Cd, Pb, Zn, Hg, Cu and Ni in heavy metals exceeds the natural background value of soil. The content of As, Cr, Pb, Zn and Cu is lower than the value specified in the secondary standard specified in GB15618-1995 Soil Environmental Quality Standard. The content of Hg and Ni is between the values specified in the second to third grades. The content of Cd exceeds the value specified by the three-level standard. The ecological risk index and the low cumulative index evaluation show that the heavy metals with relatively high risk are Cd and Hg.