bluuebunny/crossref_metadata_2025 huggingface dataset:
Hetero pregnancy. A case report
Authors: Alrowaithi Bassmah , Hakami Norah , Alwafi Buthaina
Published: April 2024

Background: Heterotopic pregnancy is a rare condition that refers to the simultaneous existence of intrauterine pregnancy (IUP) and ectopic pregnancy. It is a life-threatening condition that requires early diagnosis and prompt management.
Case Presentation: A 30-year-old African pregnant woman was presented to the emergency department complaining of severe abdominal pain, especially on the right side. She was checked for history and underwent a physical examination and ultrasound which reveals intrauterine pregnancy with right adnexal mass. While undergoing laparotomy for management of the adnexal mass, a small fetus was found; therefore, a right salpingo- oophorectomy for removal of this ectopic pregnancy was done. She was improved and discharged in good condition with a recommendation to follow up on her pregnancy. Five months later, she was admitted again as she experienced an eclamptic fit with tonic-clonic convulsion lasting for 10 minutes. She experienced a deteriorating condition that required medical termination of pregnancy. She did not improve and she was admitted to the intensive care unit and well-managed, then she improved and was shifted to the ward for observation for 10 days and then discharged in good condition.
Conclusion: The presence of IUP does not exclude the presence of ectopic pregnancy. Follow-up during pregnancy is necessary, especially if the patient is known to have previous gestational complications. Examination using transvaginal ultrasound is necessary for early diagnosis of heterotropic pregnancy (HP). Surgical treatment of HP and subsequent follow-up can contribute to maintaining IUP and its successful delivery.
Bacterial profile of urinary tract infection among pregnant women: a systematic review
Authors: Alqahtani Ahmed , Doban Rehab , Aldosari Rawa , Mgbel Afnan , Mohammed Mansour , Almansour Sultan , Sakr Abdelsalam
Published: April 2024

Urinary tract infection (UTI) is the infection and colonization of microorganisms in the urinary tract. Women carry a higher risk of being affected by UTI compared to males, especially during pregnancy due to physiological and hormonal changes. Appropriate and adequate management of UTI reduces the incidence of further maternal and fetal complications. Nonetheless, there is a growing concern regarding resistance to antibiotics among the bacteria causing UTIs in pregnant women. To identify the bacterial profile of UTIs during gestation by exploring the previous research conducted on this subject. A systematic online search was performed on scientific databases to obtain articles related to the current subject using search terms, including bacteria, profile, causative agent, sensitivity, resistance, symptomatic, pregnancy, gestation, and pregnant women. The articles of relevance were considered if they were original articles, written in the English language, available for full-text, and reporting bacterial profile of UTI during pregnancy. A total of eight articles were eligible and met the inclusion criteria. The studies were published between 2020 and 2023 and included a total number of 3,702 pregnant females from five different countries. The bacterial profile of UTI among pregnant women including symptomatic UTI, and resistance and sensitivity of bacteria to antibiotics varied between different regions. However, the causative agents of UTI displayed less variation as Escherichia coli and K.pneomniae were the major causative agents of UTI during pregnancy.
Consideraciones sobre la enseñanza-aprendizaje de los idiomas extranjeros (Con base en el enfoque cognoscitivo)
Authors: Oviedo Tito Nelson
Published: April 2024

Resumen
Introducción a un estudio del español hablado en Nariño
Authors: Balcázar de Bucher Cecilia
Published: April 2024

Resumen
Acerca de la antropología social y la semiología
Authors: Atencio Jaime
Published: April 2024

resumen
Optional features of the objective side in crimes against life and health under the legislation of some countries of the Romano-Germanic legal family (using the example of Germany and France)
Authors: Sogomonov Dmitrii Karenovich
Published: April 2024

The need for an integrated approach to the study of optional by nature signs of the objective side and their role in crimes against life and health requires turning to the experience of foreign countries. In this connection, the work examines some features of the construction of optional signs of the objective side in the above-mentioned criminal offenses in the criminal legislation of Germany and France. The conducted comparative research made it possible to see ways of improvement and vectors of development of criminal law policy, the implementation of which is carried out precisely by the correction of the criminal law. Based on the results of the work, the author indicates that legislators in Germany and France, unlike in Russia, do not attach serious importance to optional signs of the objective side when constructing crimes against life and health. At the same time, certain features in the regulation of optional signs of the objective side in crimes against life and health, which are not characteristic of domestic law, are still refined. For example, in Germany, in relation to murder in a state of passion, not only the determinants of the occurrence of a state of strong emotional excitement, but also the pre-criminal behavior of the subject of the crime are taken into account. It is also noted that the German Criminal Code regulates liability for participation in a fight; it regulates liability for abortion that occurs outside the established period of pregnancy at which it is possible. In addition, it was revealed that the French Criminal Code criminalizes hiring to commit murder if the mercenary did not plan to commit a criminal act. In conclusion, the author of the work suggests ways to improve domestic legislation taking into account the studied foreign experience.
Sociodemographic Characteristics of the Iranian Revolutionary Community in Syria and Lebanon in the 1970s.
Authors: Vishnyakova Irina Andreevna
Published: April 2024

The article is devoted to the comprehensive sociodemographic analysis of the local community of Iranian Islamists acting in Syria and Lebanon in the decade preceding the Islamic revolution of 1978-79. Thus far, history of everyday life and the multitudinous activities of the Iranian Islamic opposition in Syria and Lebanon in the 1970s has never become the principal subject of a historic research and has barely received attention from Western specialists in the history of the Islamic Revolution and modern Middle Eastern history, as well as from Iranian historians, scholars and researchers working in the field of the modern history of Iran. However, for a more comprehensive understanding of the Islamic Revolution, revolutionary processes and their logical premises and outcomes, it is highly necessary to carefully consider the sociodemographic characteristics of the active representatives of the Iranian opposition movement in the pre-revolutionary period namely in the 1970s. Throughout the comparative historical analysis of the reliable memories of longtime supporters of the Iranian Islamic movement acting in Syria and Lebanon, the fundamental sociodemographic characteristics of the active members of Iranian revolutionary movement abroad (e.g. gender, age, birthplace and place of living, educational and religious background, social marital status, etc.) are thoroughly highlighted, properly described and analyzed and their sociodemographic portrait is carefully created. The received sociohistorical data may properly serve as a valuable source on the social history of the Iranian society in the pre-revolutionary period, as well as on the complex history of Iranian revolutionary movement and the modern history of the Middle East region.
A Bayesian Approach to Low-Thrust Maneuvering Spacecraft Tracking
Authors: Zucchelli Enrico M. , Jones Brandon A.
Published: April 2024

Bayesian estimation with an explicit transitional prior is required for a tracking algorithm to be embedded in most multitarget tracking frameworks. This paper describes a novel approach capable of tracking maneuvering spacecraft with an explicit transitional prior and in a Bayesian framework, with fewer than two observations passes per day. The algorithm samples thrust profiles according to a multivariate Laplace distribution. It is shown that multivariate Laplace distributions are particularly suited to track maneuvering spacecraft, leading to a log probability function that is almost linear with the thrust. Principles from rare event simulation theory are used to propagate the tails of the distribution. Fast propagation is enabled by multi-fidelity methods. Because of the diffuse transitional prior, a novel [Formula: see text]-nearest-neighbor-based ensemble Gaussian mixture filter is developed and used. The method allows Bayesian tracking of maneuvering spacecraft for several scenarios with fewer than two measurement passes per day and with a mismatch between the true and expected thrust magnitude of up to a factor of 200. The validity domain and statistical significance of the method are shown by simulation through several Monte Carlo trials in different scenarios and with different filter settings.
Applying artificial intelligence to predict the outcome of orthodontic treatment
Authors: Ramasubbu Niranjana , Kasim Shakeel Ahmed Valai , Thavarajah Rooban , Rengarajan Krishnaswamy Nathamuni
Published: April 2024

Objectives:

The study aimed to train an algorithm to predict facial and dental outcomes following orthodontic treatment using artificial intelligence (AI). In addition, the accuracy of the algorithm was evaluated by four distinct groups of evaluators.

Material and Methods:

The algorithm was trained using pre-treatment and post-treatment frontal smiling and intraoral photographs of 50 bimaxillary patients who underwent all first bicuspid extraction and orthodontic treatment with fixed appliances. A questionnaire was created through Google form and it included 10 actual post-treatment and AI-predicted post-treatment images. The accuracy and acceptability of the AI-predicted outcomes were analyzed by four groups of 140 evaluators (35 orthodontists, 35 oral maxillofacial surgeons, 35 other specialty dentists, and 35 laypersons).

Results:

The Style-based Generative Adversarial Network-2 algorithm used in this study proved effective in predicting post-treatment outcomes using pre-treatment frontal facial photographs of bimaxillary patients who underwent extraction of all first bicuspids as part of their treatment regimen. The responses from the four different groups of evaluators varied. Laypersons exhibited greater acceptance of the AI-predicted images, whereas oral maxillofacial surgeons showed the least agreement. The base of the nose and the chin demonstrated the most accurate predictions, while gingival visibility and the upper lip-to-teeth relationship exhibited the least prediction accuracy.

Conclusion:

The outcomes underscore the potential of the method, with a majority of evaluators finding predictions made by the AI algorithm to be generally reliable. Nonetheless, further research is warranted to address constraints such as image tonicity and the proportional accuracy of the predicted images.
Assessment of Nickel Ion Release from NiTi Orthodontic Archwire After Using Magnetized Water as a Mouth Rinse
Authors: Al Zubaidy Zinah Natheer , Al Hamdany Afrah Khazal
Published: April 2024

Objectives

This study was to detect whether the magnetized water (MW), when used as a mouth rinse, can influence the release of Nickel (Ni) ions from NiTi (nickel-titanium) archwires.

Material and Methods

One hundred fifty (0.016” *0.022”) as received orthodontic NiTi archwires were grouped into three chief groups based on the used mouth rinse into MW, Ortho Kin (control positive) (OK) and distilled water (control negative) (DW) groups. Every group contained intervals of five points (24 h, 1 week, 2 week, 3 week and 4 week). Ten archwires were used for each interval. The release Ni was detected at each interval using an atomic absorption spectrometer. The topographic features of orthodontic archwires were examined with a scanning electron microscope and an atomic force microscope. SPSS Statistics software (V.19) was used for statistical analysis. One-way Analysis of Variance (ANOVA) and post hoc Duncan’s multiple range test were used for data analysis with P ≤ 0.05.

Results

Significantly less amount of Ni ion released in the MW group was recorded from NiTi archwires in comparison with the OK group for all studied intervals.

Conclusion

MW may be indicated as a suitable adjunct for further commercially available mouth rinses (as OK) throughout orthodontic therapy.
Overview on natural dyes and their IR-spectra – Part I: Plant based dyes with naphthoquinone and anthraquinone structure
Authors: Mahltig Boris
Published: April 2024

This is the first paper of a series of review articles reporting on natural dyes, their origin and infrared spectra (IR spectra). One aim of this review series is to compare IR spectra of natural dyes from different origin and discuss if this spectroscopic method can be used as versatile tool for the identification of natural dyes and their origin. This part I of the review series is related to four natural dyes based on the chemical structures of naphthoquinone and anthraquinone. Especially discussed are Lawson, juglone and alizarin, which are related to the natural products henna, walnut hull and madder root. Also, the natural dye based on alkanna root is investigated. Compared are the IR spectra of these natural dyes gained from different suppliers with the IR spectra of the pure chemical substances related to the natural dyes. A discussion with spectra from literature is supported. The aim of this review paper is to support infrared spectroscopic data of natural materials (natural dyes) to enable further material identification and also quality control supporting people working in the fields of fiber analytics or with production processes using natural dyes
Digitalization in logistics for textiles – possible fields of application for the Blockchain technology
Authors: Fohrer Natalie , Gade Andreas , Muschkiet Markus
Published: April 2024

The globalized supply chains of textiles and clothes involve multiple parties from different countries. Flows of goods, information and finances are coordinated through logistic processes, but offer potential for optimization in terms of digitalization and transparency. Incidents of the past prove that fundamental human rights standards and occupational safety are not met in global production countries yet. Legal regulations like the Act on Corporate Due Diligence Obligations for the Prevention of Human Rights Violations in Supply Chains (LkSG) shall help to improve the situation since 2023. Especially small and medium sized enterprises (SME) in Germany, to which the law applies indirectly through private-sector contracts from their non-SME consignees, struggle to control their global supply chain, to provide all necessary data and to ensure a traceable, fraud-resistant and manageable flow of information. Hence, the Center Textile Logistics investigated the potential of the Blockchain technology and its application possibilities for textile supply chains. The Blockchain technology offer chances in terms of securing clothing trademarks, proofing that standards of seals and certificates are met, proofing that political and legal regulations are met and in terms of controlling global processes that involve international suppliers and partners. However, the current state of the art of digitalization is often too low to directly apply the Blockchain technology and has to be improved first. The cost-benefit ratio has to be evaluated individually but the Blockchain technology offers great potential to rise transparency, ease communication and critical data exchange along textile supply chains.
Religionskontakte in Geschichte und Gegenwart: Aspekte eines Forschungsprogramms
Authors: Krech Volkhard
Published: April 2024

Religiöse Traditionen entstehen, sie etablieren und entwickeln sich in wechselseitiger Abhängigkeit. Dies ist zumindest die Hauptannahme des internationalen Forschungskollegs „Dynamiken der Religionsgeschichte zwischen Asien und Europa“ an der Ruhr-Universität Bochum. Der Artikel stellt zunächst konzeptuelle und methodische Überlegungen an, um sodann ein Spektrum möglicher Typen des Religionskontakts zu entwerfen. Für die Religionsforschung sind Religionskontakte nicht zuletzt deshalb von Bedeutung, weil sie einen besonders guten Fall des Religionsvergleichs in der Empirie darstellen. Von dort aus kann der religionswissenschaftliche Vergleich auf metasprachlicher Ebene erfolgen.
Cholecysto-Hydatid Cyst Fistula: Images in Medicine
Authors:   Department of Surgery, Service of Visceral Surgery 2, Military Hospital Mohamed V, Rabat, Morocco, Mahdaouy Youssef El , Njoumi Noureddine ,   Department of Surgery, Service of Visceral Surgery 2, Military Hospital Mohamed V, Rabat, Morocco, El Fahssi Mohamed ,   Department of Surgery, Service of Visceral Surgery 2, Military Hospital Mohamed V, Rabat, Morocco, Yaka Mbarek ,   Department of Surgery, Service of Visceral Surgery 2, Military Hospital Mohamed V, Rabat, Morocco, Hjouji Abderrahman ,   Department of Surgery, Service of Visceral Surgery 2, Military Hospital Mohamed V, Rabat, Morocco, AIT Ali Abdelmouaim ,   Department of Surgery, Service of Visceral Surgery 2, Military Hospital Mohamed V, Rabat, Morocco
Published: April 2024

Human hydatid disease is a zoonosis caused by the larval stage of the Echinococcus species. It is endemic in sheep and cattle raising region such as Morocco. The liver is the most frequently affected organ in echinococcosis (first filter). Cyst rupture into the biliary tree is the most common complication of hepatic hydatid cyst, seen in 5% to 15% of cases. However, fistulization between gallbladder and hydatid cystis rare. The number of cases in the literature is below 10 [1].
Spontaneous Adrenal Haemorrhage in Early Twin Pregnancy: A Case Report of Successful Conservative Management
Authors:   Departement of Visceral Surgery II, Military Hospital of Instruction Mohamed V, Rabat, Morocco, Mahdaouy Youssef El , Aziz Fadili Mohamed ,   Departement of Visceral Surgery II, Military Hospital of Instruction Mohamed V, Rabat, Morocco, Bouhtouri Yassin ,   Departement of Gynecology and Obstetrics, Military Hospital of Instruction Mohamed V, Rabat, Morocco, Benlghazi Abdelhamid ,   Departement of Gynecology and Obstetrics, Military Hospital of Instruction Mohamed V, Rabat, Morocco, Njoumi Noureddine ,   Departement of Visceral Surgery II, Military Hospital of Instruction Mohamed V, Rabat, Morocco, Ait Ali Abdelmounaim ,   Departement of Visceral Surgery II, Military Hospital of Instruction Mohamed V, Rabat, Morocco
Published: April 2024

Spontaneous adrenal haemorrhage in pregnancy is an extremely rare condition. Herein we present an additional case of unilateral spontaneous adrenal haemorrhage in a 31-year-old pregnant woman at the 15 weeks of gestation with successful conservative management and a safe vaginal delivery.
Role of CT Scan in Constrictive Pericarditis Presenting with Refractory Ascites – Review of Literature
Authors:   Assistant Professor, Pacific Institute of Medical Sciences, Umarda, Udaipur, Rajasthan, India, Sharma Rajaram , Sharma Vikash ,   Resident Doctor, Pacific Institute of Medical Sciences, Umarda, Udaipur, Rajasthan, India, Tiwari Tapendra ,   Assistant Professor, Pacific Institute of Medical Sciences, Umarda, Udaipur, Rajasthan, India, Goyal Saurabh ,   Assistant Professor, Pacific Institute of Medical Sciences, Umarda, Udaipur, Rajasthan, India
Published: April 2024

Constrictive Pericarditis (CP) is a rigid, thick noncompliant, fibrotic, and/or calcific pericardium. Early diagnosis of CP is difficult due to its vague symptoms, deceptive course and absence of usual cardiopulmonary signs. In this case report, we represent a 27-year-old male who came to our hospital with a distended abdomen and breathlessness. Because of predominant symptoms of abdominal distention and breathlessness, the patient was advised for Contrast-Enhanced Computed Tomography (CECT) of the chest and abdomen. Interestingly, the CT scan raised the possibility of constrictive pericarditis as the underlying aetiology for all of his symptoms which was confirmed using echocardiography and right heart catheterisation CP. The patient underwent surgical pericardiectomy, and the post-surgery period was uneventful; he did not require further paracentesis and was discharged in stable condition.
Strangulated Hernia with Appendicitis: A Rare Case of Amyand’s Hernia in a 72-Year-Old Man
Authors:   Department of the Emergency Surgery (UCV) - Ibn Sina University Hospital, Rabat, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco, Yousra Ouhammou , Khalil Abou elalaa ,   Department of Anesthesiology and Intensive Care, Head of the Operating Room Theatre Military Hospital Mohammed V, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco, Mohammed Dady ,   Department of the Emergency Surgery (UCV) - Ibn Sina University Hospital, Rabat, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco, Imad Laamri ,   Department of the Emergency Surgery (UCV) - Ibn Sina University Hospital, Rabat, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco, FH El Alami ,   Department of the Emergency Surgery (UCV) - Ibn Sina University Hospital, Rabat, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco
Published: April 2024

Introduction: Amyand’s hernia is an extremely rare and atypical hernia that is difficult to diagnose clinically characterised by engagement of the appendix in the inguinal sac. The aim of this report is to describe a case of Amyand’s hernia in a 72-year-old man with a history of hypertension on well-controlled calcium channel blockers, and to highlight the importance of surgical exploration in the diagnosis and management of this condition. Case Report: We present a rare case of a 72-year-old man with a history of well-controlled calcium channel blocker hypertension presenting with intermittent right inguinal pain. The patient was admitted to the hospital’s surgical emergency department and was deemed in need of surgical exploration due to suspected strangulated hernia or irreducible hernial engorgement. Preoperative examination revealed no signs of appendicitis. During surgery, an Amyand’s hernia was discovered with an inflamed appendix. Intraoperative work-up was otherwise normal. Discussion: Amyand’s hernia is an extremely rare condition, accounting for less than 1% of all adult inguinal hernias. Acute appendicitis in the context of Amyand’s hernia is even rarer, accounting for only 0.1% of all cases of acute appendicitis. This hernia may remain asymptomatic until inflammation of the appendix leads to incarceration, strangulation, necrosis, perforation or rupture. Early symptoms include inguinal tenderness and swelling. CT scanning is essential for accurate and early diagnosis of Amyand’s hernia, which can help avoid the complications of delayed surgery. Conclusion: This case highlights the importance of early CT scanning for accurate diagnosis of Amyand’s hernia with appendicitis. Management of this rare condition requires appendectomy combined with repair of the hernia, depending on the degree of inflammation of the appendix and the anatomical features of the patient.
Application of Nano-HydroxyApatite (n-HAp) for Wound Healing and Tissue Bioengineering
Authors:   BioMAT’X (HAiDARI+D+i LAB), Santiago, Chile, ZS Haidar
Published: April 2024

PRéCIS- A wound, or tissue defect can be defined as a disruption in the normal structure and function that occurs due to internal or external injury. In tissue bioengineering, natural hemostasis, and the inflammatory phase stand at the beginning of the wound and defect healing cascade. Briefly, the restorative, regenerative or reparative response to tissue injury is governed/driven by resident and circulating cells, homing to the injury site that release signals (soluble mediators) generated from the extracellular matrix. For bone defects, optimal healing can be simply classified as either primary (1o) or secondary (2o). It undergoes acascade of complex, orderly, and predictable events, that include four/five over-lapping phases: hemostasis/haematoma formation, inflammation, proliferation, callus formation (or not), and remodeling (Haversian/osteonal bone remodelling). Herein, the bone healing type is dependent on the removal of a fracture haematoma and the fixation (stabilization) strategy performed. For example, optimal stability results in 1o bone healing, with no callus formation, normal bone architecture and functional integrity restored within 3 months. On the other hand, in 2o healing, where fixation is not done, fracture haematoma, callus formation and healing via endochondral ossification ensues. Despite limitations, the main alternative for damaged or lost bone tissue replacement, restoration, regeneration, reconstruction, or repair is the autogenous bone graft, to date.
Monomer Architecture as a Mechanism to Control the Self-Assembly of Oligomeric Diblock Peptide-Polymer Amphiphiles
Authors: Allen Benjamin , Pinky Sabila , Beard Emily , Calzadilla Nicholas , Gringeri Abigail , Sanders Matthew , Knight Abigail , Yingling Yaroslava
Published: April 2024

Diblock oligomeric peptide-polymer amphiphiles (PPAs) are biohybrid materials that offer versatile functionality by integrating the sequence-dependent properties of peptides with the synthetic versatility of polymers. Despite their potential as biocompatible materials, the rational design of PPAs for assembly into multi-chain nanoparticles remains challenging due to the complex intra- and intermolecular interactions emanating from the polymer and peptide segments. To systematically explore the impact of monomer architecture on nanoparticle assembly, PPAs were synthesized with a random coil peptide (XTEN2) and oligomeric alkyl acrylates with unique side chains: ethyl, tert-butyl, n-butyl, and cyclohexyl. Experimental characterization using electron and atomic force microscopies demonstrated that tail hydrophobicity impacted accessible morphologies. Moreover, characterization of different assembly protocols (i.e., bath sonication and thermal annealing) revealed that certain tail architectures provide access to kinetically trapped assemblies. All-atom molecular dynamics simulations of micelle structure formation unveiled key interactions and differences in hydration states, dictating PPA assembly behavior. These findings highlight the complexity of PPA assembly dynamics and serve as valuable benchmarks to guide the design of PPAs for a variety of applications including catalysis, mineralization, targeted sequestration, antimicrobial activity, and cargo transportation
Catalyst Supraparticles: Tuning the Structure of Spray-dried Pt/SiO2 Supraparticles via Salt-based Colloidal Manipulation to Control their Catalytic Performance
Authors: Groppe Philipp , Reichstein Jakob , Carl Simon , Cuadrado Collados Carlos , Niebuur Bart-Jan , Zhang Kailun , Apeleo Zubiri Benjamin , Libuda Jörg , Kraus Tobias , Retzer Tanja , Thommes Matthias , Spiecker Erdmann , Wintzheimer Susanne , Mandel Karl
Published: April 2024

The structure of supraparticles (SP) is a key parameter for achieving advanced functionalities arising from the combination of different nanoparticle (NP) types in one hierarchical entity. However, whenever a droplet-assisted forced assembly approach is used, e.g., spray-drying, the achievable structure is limited by the inherent drying phenomena of the method. Especially, mixed NP dispersions of differently-sized colloids are heavily affected by segregation during the assembly. Herein, the influence of the colloidal arrangement of Pt and SiO2 NPs within a single supraparticulate entity is investigated. A salt-based electrostatic manipulation approach of the utilized NPs is proposed to customize the structure of spray-dried Pt/SiO2 SPs. By this, size-dependent separation phenomena of NPs during solvent evaporation, that limit the catalytic performance in the reduction of 4-nitrophenol, are overcome by achieving even Pt NP distribution. Additionally, the textural properties (pore size and distribution) of the SiO2 pore framework are altered to improve the mass transfer within the material leading to increased catalytic activity. The suggested strategy demonstrates a powerful, material-independent, and universally applicable approach to deliberately customize the structure and functionality of multi-component SP systems. This opens up new ways of colloidal material combinations and structural designs in droplet-assisted forced assembly approaches like spray-drying.
Local structure and dynamics in MPt(CN)6 Prussian blue analogues
Authors: Harbourne Elodie , Barker Helena , Guéroult Quentin , Cattermull John , Nagle-Cocco Liam , Roth Nikolaj , Evans John , Keen David , Goodwin Andrew
Published: April 2024

We use a combination of X-ray pair distribution function (PDF) measurements, lattice dynamical calculations, and ab initio density functional theory (DFT) calculations to study local structure and dynamics in various MPt(CN)6 Prussian blue analogues. In order to link directly the local distortions captured by the PDF with the lattice dynamics of this family, we develop and apply a new `interaction-space' PDF refinement approach. This approach yields effective harmonic force constants, from which the (experiment-derived) low-energy phonon dispersion relations can be approximated. Calculation of the corresponding Gr¨neisen parameters allows us to identify the key modes responsible for negative thermal expansion (NTE) as arising from correlated tilts of coordination octahedra. We compare our results against the phonon dispersion relations determined using DFT calculations, which identify the same NTE mechanism.
Exploring ssDNA translocation through alpha-hemolysin using Coarse-Grained Steered Molecular Dynamics
Authors: Okyay Cagla , Dessaux Delphine , Ramirez Rosa , Mathé Jérôme , Basdevant Nathalie
Published: April 2024

Protein nanopores have proven to be effective for single-molecule studies, particularly for single-stranded DNA (ssDNA) translocation. Previous experiments demonstrated their ability to distinguish differences in purine and pyrimidine bases and in the orientation of the ssDNA molecule inside the nanopore. Unfortunately, the microscopic details of ssDNA translocation over experimental time scales, which are not accessible through all-atom molecular dynamics (MD), have yet to be examined. However, coarse-grained (CG) MD simulations enable systems to be simulated over longer characteristic times closer to experiments than all-atom MD. This paper studies the ssDNA translocation through alpha-hemolysin nanopore exploiting steered MD using MARTINI CG force field. The impact of sequence length, orientation inside the nanopore and DNA charges on translocation dynamics as well as the conformational dynamics of ssDNA during the translocation are explored. Our results highlight the efficacy of CG molecular dynamics in capturing experimental properties of ssDNA translocation, including a wide distribution in translocation time per base. In particular, the phosphate charges of the DNA molecule are crucial in the translocation dynamics and impact the translocation rate. Additionally, the influence of the ssDNA molecule orientation on the translocation rate is explained by conformational differences of ssDNA inside the nanopore during its translocation. Our study emphasizes the significance of sufficient statistics via CG MD, which can elucidate the great variety of translocation processes.
Ecological preferences of the Swiss pine (Pinus cembra L.) forests in the Gorgany Nature Reserve
Authors: Kuznetsov R.
Published: April 2024

Swiss pine (Pinus cembra L.) is a montane Carpathian (Alpine-Carpathian) species. The modern distribution of the Swiss pine is disjunct, the two isolated areas are located in western and central Europe (Alps) and the middle and high mountains of the Carpathians. The largest areas of Swiss pine in Ukraine are preserved in the Gorgany region at the altitude of 1250‒1450 m above sea level, where it forms the upper forest line. In the Gorgany Nature Reserve, P. cembra grows in the altitude range from 1070 to 1475 m ASL. The lower boundary, in the form of individual trees, descends to 1000 m ASL, and the upper boundary rises to 1585 m ASL. To define the ecological preferences of the Swiss pine, a series of route surveys were conducted and research sites (permanent forest monitoring plots, stationary research profiles, and stationary areas for the counting of natural forest regeneration) were established. The study of the plant communities with P. cembra on the southwestern slopes of the Dzhurdzhi tract showed the dependence of the forest species composition on the altitude above sea level. The forest stands quantitative composition and productivity are also significantly influenced by slope exposure. The proportion of P. cembra in the forests on steep slopes (30‒55°) of west and north-west exposure is relatively high (from 17.1% to 49.0%). Under other conditions, the proportion of P. cembra in the stand composition gradually decreases. Swiss pine is almost completely absent on the slopes of eastern and northern exposures except for rare single trees in Pinus mugo Turra scrub on northern slopes. The forests with P. cembra are typical of sunny slopes where the available sum of active temperatures ranges between 1000° and 1400° and the average ambient temperatures from -12.2°С to +16°С. The optimal environmental conditions for the relict species P. cembra in the Dovbushanski Gorgany region are on the western slopes with a steepness of 17‒55° and southwestern and northwestern slopes with a steepness of 35°‒42°. In terms of soil fertility, oligotrophic edaphotopes with moderate moisture are optimal for the growth of Swiss pine.
Breeding value and homeostaticity of the spike performance and its constituents in medium tall winter bread wheat (Triticum aestivum L.) accessions in relation to resistance to the pathogens of powdery mildew (Blumeria graminis (DC.)...
Authors: Yarosh A. , Riabchun V. , Solonechna O.
Published: April 2024

Identification of sources of group resistance in winter bread to the pathogens B. graminis (DC.) E.O. Speer f. sp. tritici Em. Marchal and S. tritici Rob. et Desm. and of high performance of the spike and its constituents is a necessary and relevant step towards the creation of comprehensively valuable and adaptable genotypes. The paper presents the results of evaluation of the breeding value and homeostaticity of the spike performance and its constituents in medium tall winter bread wheat in relation to resistance to powdery mildew and Septoria leaf blotch. New sources of consistently high group resistance to the powdery mildew and Septoria leaf blotch pathogens have been identified: Kyivska 17, Zorianka, Sicheslava, and Svitiaz (UKR). We have selected accessions with high performance of the spike and its constituents in combination with high breeding value and homeostaticity of these characteristics: the kernel weight per spike (Kyivska 17 (Sc = 1.8; Hom = 21.9) (UKR)); the kernel number per spike (Svitohliad (Sc = 37.8; Hom = 554.1), Stritenska (Sc = 36.4; Hom = 452.5), Svitiaz (Sc = 35.8; Hom = 451.8), MIP Lada (Sc = 33.6; Hom = 572.7) (UKR), and Manella (Sc = 33.1; Hom = 460.8) (NLD)); and the thousand kernel weight (Kyivska 17 (Sc = 42.9; Hom = 1053.7), Sicheslava (Sc = 42.6; Hom = 873.2) (UKR), and Turanus (Sc = 41.3; Hom = 707.5) (AUT)). It was found that the percentage of accessions with high homeostaticity of the thousand kernel weight, the kernel number per spike and the kernel weight per spike was 63.6%, 31.8%, and 22.7%, respectively. In the medium tall winter bread wheat accessions, there were strong positive correlations between the breeding value of the kernel weight per spike and resistance to Septoria leaf blotch (r = 0.77, P < 0.01) and between the kernel number per spike and resistance to powdery mildew (r = 0.71, P < 0.01). Significant positive correlations were observed between the breeding value of the thousand kernel weight and resistance to Septoria leaf blotch (r = 0.61, P < 0.01), between the homeostaticity of the thousand kernel weight and resistance to Septoria leaf blotch (r = 0.51, P < 0.01) and between the breeding value of the kernel number per spike and resistance to Septoria leaf blotch (r = 0.56, P < 0.01). The selected sources of high group resistance to powdery mildew and Septoria leaf blotch, high performance of the spike and its constituents in combination with the breeding value and homeostaticity of these traits are valuable starting materials to create highly promising winter bread wheat cultivars, which would be adaptable to limiting biotic factors.
Paley Wiener Theorem on a Reductive Lie Group
Authors: Zoto Bi Neantien Claudio , Kinvi Kangni
Published: April 2024

Let G be a locally compact group, K a maximal compact subgroup of G and δ on arbitrary class of irreducible unitary representations of K. The spherical Grassmannian Gp,δ is an equivalence class of spherical functions of type δ−positive of height p. In this work, we give an extension of orbital integral with respect to δ, when G is reductive Lie group. Moreover, if the discret serie is not empty, we give an extension of Paley-Wiener theorem using a compact Cartan subgroup of G.
A medicina tradicional:O uso de subprodutos do coco babaçu com fins terapêuticos pelas populações tradicionais do município de Codó-Maranhão.
Authors: Oliveira Aysha Santiago De , Nunes Bruno de Almeida
Published: April 2024

INTRODUÇÃO: A medicina tradicional engloba práticas de cura que se desenvolveram ao longo do tempo, correlacionando valores culturais e a prática médica dentro de uma comunidade específica, incluindo
INTEGRANDO A AVALIAÇÃO GERIÁTRICA AMPLA NOS CUIDADOS PALIATIVOS EMERGENCIAIS PARA PACIENTES IDOSOS
Authors: Martins Marcelo
Published: April 2024

A integração da Avaliação Geriátrica Ampla (AGA) nos cuidados paliativos emergenciais para pacientes idosos representa uma abordagem essencialmente holística e multidimensional, visando compreender pr
IMPLANTAÇÃO DO ENSINO REMOTO EM TEMPOS DE PANDEMINA EM UMA GRANDE INSTITUIÇÃO DE ENSINO
Authors: Daroncho Celio , Biazotto Luiz Henrique , Oliveira Aldy Salvino de
Published: April 2024

Este estudo aborda a rápida transição para o ensino remoto nas instituições de ensino do Estado de São Pauloadministradas pelo Centro Paula Souza (CPS), em resposta à pandemia de COVID-19, destacando a implementação do Microsoft Teams como plataforma de ensino. A metodologia envolveu a análise das necessidades das Escolas Técnicas Estaduais (Etecs) e das Faculdades de Tecnologia (Fatecs), a padronização dos nomes das equipes, a definição dos tipos de equipes e a criação das equipes por meio de script via PowerShell e posteriormente utilizando o School Data Sync (SDS). Os resultados demonstraram que, embora a solução inicial tenha sido desafiadora devido à urgência e complexidade das estruturas acadêmicas, a adoção do SDS agilizou o processo, reduzindo erros e retrabalho. No entanto, sugere-se que a integração dos Sistemas Acadêmicos (SAs) com o Teams por meio de uma API seja a abordagem ideal para facilitar a criação e gestão das equipes em tempo real, o que está em desenvolvimento para implementação futura em 2022. Essa transição para o ensino remoto enfatiza a importância da infraestrutura adequada e do planejamento eficaz para garantir a continuidade das atividades educacionais durante crises emergenciais.
LOGÍSTICA REVERSA MEDICAMENTOS VENCIDOS E EM DESUSO: UMA COMPARAÇÃO ENTRE AS LEGISLAÇÕES DE BRASIL E MÉXICO
Authors: MANSO BARBARA AP.  DAS NEVES , SÁ STEPHANIE RIBEIRO DE , FERREIRA TALITHA GOMES , LOPES MAICK ROBERTO
Published: April 2024

A logística reversa é um conceito que vem ganhando popularidade em todo o mundo para promover a gestão sustentável de resíduos e recursos naturais. Logística Reversa é especialmente importante para o gerenciamento adequado de medicamentos vencidos ou descartados, pois representam riscos significativos à saúde pública e ao meio ambiente. Diante desse cenário, este artigo tem como objetivo comparar as legislações brasileira e mexicana sobre logística reversa de medicamentos vencidos e obsoletos, identificar possíveis semelhanças e diferenças. Com base em revisão sistemática da literatura e análise comparativa das legislações dos dois países, este estudo é descritivo e analítico. Para tanto, são utilizadasfontes primárias e secundárias, incluindo legislação vigente, artigos, livros, relatórios governamentais e outras publicações relevantes. Como resultado, pôde-se perceber a importância de uma entidade para implementação e operacionalização do sistema de logística reversa de medicamentos em todo o território nacional, enquanto o papel do governo é fiscalizar e impor sanções àqueles que não cumprirem a legislação e ainda criar mecanismos de conscientização da população para mitigar os impactos desses resíduos no meio ambiente.
ESTUDO DE CASO: APLICAÇÃO DA ROTEIRIZAÇÃO PARA RESOLVER O PROBLEMA DE ENTREGA DE CESTAS BÁSICAS
Authors: BAPTISTA MATHEUS AUGUSTO , SANTOS EMERSON FRANCIS MONTEIRO DOS , MENDES OSWALDO LÁZARO
Published: April 2024

A cartografia, definida como a utilização de mapas para a localização por meio de figuras geométricas e simples em baixa escala, de uso comum na antiguidade, era a principal forma para locomoção e montagem de rotas a fim de realizar entregas, porém devido a sua baixa precisão e difícil manuseio hodiernamente estetorna-se obsoleto, sendo substituído por formas atuais de roteirização via GPS. Por meio de um estudo de caso logístico, baseado em uma metodologia qualitativa, é proposto a melhoria nas rotas de uma empresa de grande porte nascida no interior do sudeste brasileiro, utilizando como principal ferramenta, o Solver aplicação presente no Microsoft Excel, visando a diminuição de custos, porém tendo ganho operacional, para a entrega de cestas básicas em suas filiais, o desenvolvimento do projeto ocorreu em conjunto com a metodologia Design Thinking, desejando-se criar um maior vínculo com o problema para administração de recursos e melhorias, com os resultados, foi possível obter uma otimização significativa em quantidade de quilômetros a serem percorridas nas rotas da cooperativa, concluindo assim a importância de um bom planejamento logístico para a redução de custos.
A CABOTAGEM COMO ALTERNATIVA PARA REDUÇÃO DE EMISSÃO DE CO2 NO TRANSPORTE DE CARGA BRASILEIRO - ESTUDO DE CASO
Authors: PASSOS GEOVANA LISSA MOREIRA , FIDELIS JANICE DA SILVA , FORMIGONI ALEXANDRE , MALTA REGIANE DE FÁTIMA BIGARAN
Published: April 2024

Os processos de logística de transportes buscam tornar a cadeia de suprimentos mais sustentáveis e isso faz com que o interesse por esses processos aumente cada vez mais, já que esse tipo de logística impacta menos o meio ambiente, reduzindo custos e agregando valor ao produto, sendo assim, uma vantagem competitiva, em meio a consumidores que buscam por produtos mais sustentáveis. Nesse sentido, esse artigo apresenta o processo transporte de uma empresa multinacional francesa do ramo de eletroeletrônicos, que faz operação de transporte via rodoviário em todo o país. A empresa estabeleceu um grande desafio: contribuir com as metas do Acordo de Paris (COP21), que visa a redução da emissão de gases de efeito estufa. Desta forma, foi projetado a troca do modal rodoviário para cabotagem em uma operação que transfere produtos de uma planta em São Paulo para Manaus, com objetivo de reduzir a emissão de dióxido de carbono na atmosfera. Para tanto, foi realizado um estudode caso, com intuito de entender e mapear o funcionamento desses processos, bem como uma análise quantitativa com base em dados fornecidos pela empresa, utilizados para calcular o custo do frete e a quantidade de CO2 emitida em ambos os processos de transferência, com a finalidade de identificar qual modal é mais sustentável. Os resultados apontam a eficiência ambiental do modal hidroviário e sugere também melhor rentabilidade quanto ao frete ton/km transportado.
Insetos de interesse médico
Authors: Rios Flávia Geovana Fontineles , Meireles Anne Caroline Alves , Feitoza Luiz Henrique Maciel , Silva Michelli Santos da , Paz Matheus de Araújo , Silva Lucas Rosendo da , Velásquez Claudia María Ríos , Pessoa Felipe Arley Costa , Oliveira Marcela Alvares , Julião Genimar Rebouças , Medeiros Jansen Fernandes de
Published: April 2024

A cartilha "Insetos de Interesse Médico" aborda diversos insetos que podem transmitir doenças aos seres humanos e animais, com foco especial nos mosquitos da dengue, barbeiros e outros vetores de doenças. Os autores, pesquisadores da Fiocruz Rondônia e Fiocruz Amazonas, apresentam informações sobre a prevenção e combate a esses insetos, destacando a importância da saúde única, que considera a interação entre a saúde humana, animal e ambiental. O projeto "Saúde Única de Igarapés" visa estudar a biodiversidade de Porto Velho e suas relações com o ambiente, visando a sensibilização da população quanto à prevenção das doenças transmitidas por insetos. A cartilha também fornece orientações práticas para evitar a proliferação desses insetos e reduzir o risco de doenças.
A Complex Case with a Completely Percutaneous Solution: Treatment of a Severe Calcific Left Main in a Patient with Low-Flow Low-Gradient Aortic Stenosis
Authors: Renatomaria Bianchi , Giovanni Marco Esposito , Giovanni Ciccarelli , Donato Tartaglione , Paolo Golino
Published: April 2024

Background: This case study explores an integrated approach to managing a complex cardiac condition, presenting a comprehensive single-session intervention. This includes balloon valvuloplasty using a Nucleus 18 mm balloon, complex angioplasty with rotational atherectomy (rotablator) targeting calcified lesions in the left main and left anterior descending artery, and Transcatheter Aortic Valve Implantation (TAVI) with a 23 mm Sapien 3 valve, all performed on an 81-year-old woman. Furthermore, this report underscores the strategic left atrial appendage closure conducted three months post-procedure due to the patient’s elevated hemorrhagic risk. Case presentation: Facing critical coronary and valvular pathologies, the patient underwent a meticulously planned, single-session intervention. The process began with a balloon valvuloplasty using a Nucleus 18 mm balloon to address the aortic stenosis. This was followed by a high-risk angioplasty, during which the Impella CP device provided hemodynamic support and rotational atherectomy was employed to address the calcified coronary artery disease effectively. The same session saw the successful execution of TAVI using a 23 mm Sapien 3 valve. The comprehensive approach notably diminished procedural complications, illustrating the benefits of an integrated treatment pathway in managing high-risk patients. Three months later, the patient underwent a left atrial appendage closure, a critical move considering her high risk of hemorrhage. This procedure also provided an opportunity to assess the favorable outcomes of the previous angioplasty. Conclusion: This case validates the feasibility and efficacy of performing multiple advanced percutaneous interventions in a single session for high-risk cardiac patients. It underscores the crucial role of innovative and personalized treatment strategies in improving patient outcomes, particularly in complex clinical scenarios. Moreover, the case exemplifies the essential relationship between immediate, comprehensive intervention and subsequent follow-up procedures in ensuring optimal long-term patient care.