bluuebunny/crossref_metadata_2025 huggingface dataset:
Mouth Breathing: Understanding the Pathophysiology of an oral habit and its consequences
Authors: Ramirez-Yanez German
Published: February 2023

Mouth breathing is a sign associated with Sleep and Breathing related Disorders and Obstructive Sleep Apnea in children. The aim of this paper is to provide a comprehensive overview of the changes in the human physiology when mouth breathing and, how it may affect the oral and general health in humans. The potential reactions produced at the cellular level and, how those reactions may lead to a negative impact in the human health are presented. Mouth breathing affects the O2/CO2 exchange at the lungs, which may lead to the production of the Hypoxia Inducible Factor (HIF) in all the cells in the human body, as well as stimulates the production of Erythropoietin in the kidney. Mouth breathing also causes a major loose of CO2, which increases the production of bicarbonates in the kidney and release of essential minerals through the urine. All those reactions may facilitate the development and progression of chronic diseases in humans. It is recommended to consider mouth breathing as an oral habit that may associate with a cascade of events in the human physiology leading to chronic health problems. The health professionals should consider mouth breathing as a health risk factor and treat it as early as possible.
Cholesterol-Dependent Cellular Processes and Peptides Containing Cholesterol-Binding Motifs: Possible Implications for Medicine
Authors: Dunina-Barkovskaya Antonina
Published: February 2023

The animal cell is a unique system in which the functioning of its constituent molecules is interdependent and coordinated, and the violation of this coordination is fatal for the cell. One example of this coordination and mutual regulation is the functioning of membrane proteins, whose activity depends on their interaction with membrane lipids. This review reminds us of the crucial importance of the lipid component of cell membranes for normal cell function, and in particular looks at the role of the "cholesterol" component. Given a given genome and a corresponding set of proteins, this lipid component provides a wide range of regulation of cellular functions. The review exemplifies cholesterol-dependent membrane proteins and cellular processes and considers their role in microbial infections and some other pathologies. The concept of cholesterol-recognizing/interacting amino acid consensus (CRAC) motifs in proteins as a possible mechanism of these protein–lipid interactions is discussed. Examples of the use of peptides containing such motifs to modulate cholesterol-dependent processes are presented. In summary, consideration of the cholesterol component in disease pathogenesis and understanding the mechanisms of cholesterol–protein interactions represent a significant resource for the development of drugs that affect the protein–lipid interface. Such drugs may include cholesterol-binding peptides that target specific cholesterol-dependent proteins.
Recent advances in sunscreen agents and their formulations: A review
Authors: Mewada Rajvee , Shah Yamini
Published: February 2023

Ultraviolet radiation (UVR) has been shown to cause skin disorders, including sunburn and symptoms such as erythema, ageing and formation of wrinkles, pigmentation or dyspigmentation, DNA damage and ultimately photocarcinogenesis on prolonged exposure. It has been reported that sunscreens have beneficial effects in reducing the incidence of skin disorders and protect the skin against exogenous and endogenous harmful agents by absorption, scattering and by blocking phenomena. Ultraviolet (UV) rays are divided into three wavelength categories: UV-A, UV-B and UV-C. Skin exposure to sunlight and other climatic conditions induces the formation of reactive oxygen species (ROS), which can react with DNA, proteins, and fatty acids in the skin, resulting in oxidative damage and damage of the antioxidant system in the human body. Such injuries disrupt the skin’s regulation pathways, resulting in photoaging and the development of skin cancer. Active ingredients in sunscreen agents are synthetic substances which are classified into organic and inorganic filters. Synthetic agents have a number of serious side effects. As a result, to overcome this deleterious effects natural sunscreens were found by the researchers from nature. Natural products can be used as sunscreens and have healing, softening, rejuvenating, and sun protection properties. However, the use of sunscreen has a number of drawbacks, including inducing photoallergic dermatitis, environment pollution, and deficiency of vitamin D production. Therefore, consumers should use appropriate herbal formulations to improve sun protection as well as to avoid the side effects of synthetic sunscreens.
Recent advances in the biological activity of quinazoline
Authors: Nagrale Sudarshan , Pondkule Amit , Babar Vishal
Published: February 2023

The aim of this review is to produce an outline of numerous pharmacologic activities of quinazoline moiety. Quinazoline has become a famous topic up of two fused six-membered simple aromatic rings, a benzene ring and a pyrimidine ring because of its manifold uses. various quinazoline derivatives have been found to gives a broad spectrum of biological activities, which stimulated the research activity in this field. Quinazolines and its derivatives represent one in all the foremost active categories of compounds, that possess wide selection of biological activities like anti-bacterial, analgesic, anti-microbial, anti-inflammatory drug, anticancer, and anti-hypertensive, antifungal, anti-HIV, inhibitor, analgesic, medicament, antiprotozoal, antitumor, anti-tubercular activities. This review is an effort to magnify the immense potentiality of this ring system. This study may accelerate the designing process to come up with a lot of range of therapeutically viable clinical candidates.
Calculation of density, viscosity, and conductivity for Na(K)BH4 – Na(K)BO2 – Na(K)OH – H2O solutions used in hydrogen power engineering
Authors:   Saratov State University, Churikov Aleksei Vladimirovich , Ivanishchev Aleksandr Viktorovich ,   Saratov State University, Gamayunova Irina Mikhailovna ,   Saratov State University, Ushakov Arseni Vladimirovich ,   Saratov State University, Churikov Mikhail Alekseevich ,   Saratov State University
Published: February 2023

Concentrated water-alkaline mixtures of sodium and potassium borohydrides and borates are used as fuel and a hydrogen source in hydrogen power engineering, including low-temperature fuel cells. The performance of such mixtures is determined by their physicochemical properties. An algorithm to calculate the density, viscosity, and specific electric conductivity of mixed solutions of the five-component water + salt system (Na,K)BH4 + (Na,K)BO2 + (Na,K)OH + H2O based on the quasiadditivity of these properties is proposed. The concentration-temperature dependences of the density, viscosity, and specific conductivity of aqueous KOH, NaOH, KBO2, NaBO2, NaBH4, and KBH4 solutions of any composition in a temperature range of (0 to 60)°C and the whole concentration range are described mathematically. The technique and algorithm of calculation have been verified by comparison with measured properties.
Methodical maintenance impedance spectroscopy for lithium chemical power sources
Authors:   Institute of Physical Chemistry and Electrochemistry of A. N. Frumkina of RAS, Petrenko Elena Mikhailovna , Lukovtsev Vyacheslav Pavlovich ,   Institute of Physical Chemistry and Electrochemistry of A. N. Frumkina of RAS, Dribinskii Aleksandr Veniaminovich ,   Institute of Physical Chemistry and Electrochemistry of A. N. Frumkina of RAS, Klyuev A. L. ,   Institute of Physical Chemistry and Electrochemistry of A. N. Frumkina of RAS
Published: February 2023

The possibility of the use of impedance spectroscopy using an impulse method of step current change and recording voltage change in during time at the terminals of a cell with subsequent Fourier transform of the input signal and the response to it to assess the current state of Li-cell. It is proposed use of current pre-impulse in order to minimize the influence of passive film. It is substantiated an algorithm based on the measurements of impedance phase for determining of residual capacity.
Holms Heart in a Fetus with Maternal Anticonvulsant Drug Exposure: A Case Report
Authors: Golbabaei Alireza , Naemi Mahsa , Saleh Maasoumeh
Published: February 2023

Double inlet left ventricle (DILV) is a rare congenital cardiac malformation that is defined as an anomaly with univentricular atrioventricular (AV) connection, and single ventricular morphology. This variation can be associated with the inlet and outlet cardiac abnormalities. In the current report, we present a case of Holms heart, as a rare variant of double-inlet left ventricle.
Acute Necrotizing Encephalopathy Following Presumed COVID-19 Infection: The First Iranian Report in Children
Authors: Babaei Meisam , Hosseini Susan , Tavakoli Maryam , Banaei Mahnaz , Bagheri Maryam
Published: February 2023

In the fifth’s SARS-CoV-2 infection peak, although extended vaccination, still there is some reports of neurologic complications of covid-19 in children like adult. Though often we expose to benign neurologic features but sometimes there is unusual clinicoradiologic presentation. Thus, report of uncommon neurologic manifestations can help us to better understand of main pathophysiology in pediatric brain involvement. In this report, we present a five-year- old previously healthy girl that arrive to our hospital with fever, vomiting and loss of consciousness, on lumbar puncture there was mild protein elevation without poleocytosis and nasopharyngeal swap PCR for COVID-19 was positive. Brain imaging 10 hours after admission, revealed findings suggestive of acute necrotizing encephalopa thy (ANE). In spite of extensive brain involvement, after prompt initiation of high dose methylprednisolone and IV immunoglobulin, there was dramatic improvement after 3 months’ follow-up. To our knowledge, this is the first Iranian report and the second report on the world.
Successful Pregnancy in A Patient with Fontan Surgery: A Case Report
Authors: Zamansaraei Shadi , Nazari Sabet Milad , Bahrami Parvin
Published: February 2023

The Fontan operation is a palliative procedure for patients with several forms of congenital heart disease unsuitable for biventricular circulation, especially tricuspid valve atresia. In this procedure, the vena cava flow is directed to the pulmonary arteries bypassing the ventricle. Pregnant patients with Fontan surgery in their post-surgical history have more maternal risks. We should counsel patients with saturations <85%, depressed ventricular function, refractory arrhythmia, or protein-losing enteropathy against pregnancy (mWHO; IV). In this study, we review a pregnant case that has successful pregnancy and Fontan palliation and lv systolic heart failure (LVEF: 35%) in her past medical history.
Isolated Painful Oculomotor Nerve Palsy as a Rare Complication of the Sinopharm COVID-19 Vaccine: A Case Report and Review of the Literature
Authors: Paybast Sepideh , Moghadasi Abdorreza Naser
Published: February 2023

There are limited reports of oculomotor nerve palsy following vaccination. Herein, we aimed to report a case of acute oculomotor nerve palsy following the first dose of the Sinopharm vaccine. A 17-year-old woman presented with a history of acute painful diplopia and right ptosis within a week after receiving the first dosage of the Sinopharm vaccine. The neurological examination was compatible with acute right third nerve palsy sparing pupils. All the para-clinical tests were unremarkable. With a diagnosis of possible oculomotor nerve palsy as an adverse event of the COVID-19 vaccine, she was treated with steroids leading to a significant recovery. We reported the first case of acute oculomotor nerve palsy associated with the Sinopharm vaccine. However, our findings dose not conclude a causal association between oculomotor nerve palsy and COVID-19 vaccination.
Advances in breeding for improved cultivars of turfgrass
Authors:   University of Georgia, USA, Vines Phillip L. , Chandra Ambika ,   Texas A&M AgriLife Research, USA, Tate Trent M. ,   GO Seed, Inc., USA
Published: February 2023

Turfgrass breeding efforts are aimed at developing new turfgrass varieties adapted to a wide range of geographic regions with excellent seed or sod production, improved stress and pest tolerance, and elite turf quality under high, medium, and low maintenance practices. Various cooperative testing programs are available and utilized by turfgrass breeders to expedite these efforts. In addition, new technologies and advanced breeding strategies are being developed for enhanced DNA genotyping and high-throughput plant phenotyping approaches to improve turfgrass breeding and selection efficiency. This chapter discusses biological characteristics, traditional breeding strategies, current breeding objectives, and advanced breeding methods for the major cool- and warm-season turfgrass species. Although remarkable progress has been made in the development of improved turfgrass cultivars, much work remains to deliver turfgrass varieties that are able to withstand the stresses of the future.
Advances in maintenance practices of turfgrass
Authors:   Iowa State University, USA, Thoms Adam W. , Lindsey Alex J. ,   University of Florida, USA
Published: February 2023

Turfgrass management has greatly changed over time. Advancements in technology have resulted in changes to management practices including autonomous mowers, lightweight rolling on putting greens and fairways, vertical mowing, air injections, and fraise mowing for renovation to name a few. These practices have lowered the need for chemical inputs through improving the health and density of turfgrass stands. Continued changes in turfgrass maintenance will follow technology advances in turfgrass equipment, and should make turfgrass maintenance more sustainable in the coming years.
Advances in abiotic stress management in turfgrass
Authors:   Oklahoma State University, USA, Fontanier Charles , Segars Chrissie A. ,   Texas A&M University, USA
Published: February 2023

Abiotic stresses of turfgrasses involve any environmental condition which limits plant growth, turfgrass quality, and system functionality. Commonly observed abiotic stresses in turfgrass systems include drought, high temperature, low temperature, low irradiance, traffic, salinity, and chemical phytotoxicity. Managing abiotic stresses with reduced irrigation, fertilizer, energy, and pesticides has become critical to the sustainability of the turfgrass industry. In this chapter, we aim to describe the current literature related to abiotic stress management in turfgrasses with an emphasis on sustainability of turfgrass systems. To this end, we have organized the discussion into four approaches to sustainable abiotic stress management: 1) managing growth, 2) moderating the environment, 3) enhancing stress tolerance, and 4) masking stress response.
Advances in biostimulants in turfgrass
Authors:   Pennsylvania State University, USA, Fidanza Michael , Bigelow Cale ,   Purdue University, USA, Kostka Stanley ,   Pennsylvania State University, USA, Ervin Erik ,   University of Delaware, USA, Gaussoin Roch ,   University of Nebraska-Lincoln, USA, Rossi Frank ,   Cornell University, USA, Cisar John ,   Cisar Turfgrass Research Service, USA, Dinelli F. Dan ,   North Shore Country Club, USA, Pope John ,   Pope Soils Consulting and Counseling Services, USA, Steffel James ,   Lehigh Agricultural and Biological Services, USA
Published: February 2023

This chapter reviews the use of biostimulants in turfgrass management. It first identifies the different types of biostimulants that can be used for turfgrass, focusing on phytohormones, biopolymers, protein hydrolysates and other nitrogen-containing compounds, botanical and synthetic bioactive compounds. The chapter also highlights the possibility of using humic substances, organics, inorganics/minerals, biologicals/microbials, soil surfactants and other naturally derived or synthetic bioactive compounds.
Considerations with selecting turfgrass varieties and cultivars
Authors:   National Turfgrass Evaluation Program, USA, Morris Kevin , Qu Yuanshuo ,   Rutgers, The State University of New Jersey, USA, Kne Len ,   University of Minnesota, USA, Graham Steve ,   University of Minnesota, USA
Published: February 2023

The National Turfgrass Evaluation Program (NTEP) conducts trials of turfgrass species across the USA and Canada. NTEP data collected since 1981 is publicly available at www.ntep.org. Data is collected on more than 100 parameters including key factors in sustainable turfgrass selection. Selection of turfgrasses with traits such as improved disease resistance, drought tolerance, persistence under poor soil conditions or low quality irrigation and fast establishment are shown to protect the environment, improve athlete safety, reduce inputs, thus improving sustainability. To improve access to sustainable turfgrass data, NTEP and the University of Minnesota have developed a relational database along with a user-friendly selection tool, the Turfgrass Trial Explorer. This tool is accessed at www.ntep.org/database.htm, which allows for additional selection, sorting, analyzing and downloading of NTEP data. Case studies are presented to demonstrate current and future use of the Turfgrass Trial Explorer for sustainable turfgrass selection.
Constitutionalism and Human Rights: A Critical Analysis of the Rights of Transgender People in India
Authors: Khanna Purnima
Published: February 2023

The movement for decriminalizing homosexual relations and the human rights of the LGBT community has gained momentum in the last decade. In India, various NGOs and LGBT society have fought a long battle demanding the decriminalization of homosexuality and declaring sexual orientation as part of the fundamental right to life under Article 21 of the Indian Constitution. This paper explored the Indian legislative framework dealing with transgender people. Furthermore, it extensively covered the landmark judgments delivered by the Indian judiciary on the subject matter and highlighted that these judgments had played an essential role in uplifting the cause and protecting the fundamental rights of transgenders. Using doctrinal research as its methodology, this study showed that the Indian Constitution essentially provides a fundamental right to equality under Article 14, whereas Articles 15 and 16 outline that no one shall be discriminated on the ground of sex. Also, the Indian judiciary had decriminalized Section 377 of the Indian Penal Code, considered as part of landmark judgments that recognize transgender people as a third gender. India also enacted the Transgender Protection Act 2019 to ensure the rights of transgenders. However, this Act failed to address the issue of forced sex-reassignment surgeries, which had been imposed upon transgender people against their consent. On the other hand, while transgenders are legally protected, gaining acceptance from society is another arduous task in which transgenders have struggled to realize an all-inclusive and non-judgmental environment towards persons with different sexual orientations.
Application of Fuzzy TOPSIS Method as a Decision Support System for Achievement Student Selection
Authors: Anggoro Vani Krismo , Riski Abduh , Kamsyakawuni Ahmad
Published: February 2023

Achievement student selection aims to appreciate students who have achieved an achievement, both in the academic and non-academic fields. This activity is carried out in stages, starting from departments, faculties, and universities, to the national level. In the selection process, several criteria were used: GPA, scientific work, presentation, English, and achievements were featured and involved several juries to avoid subjectivity in the assessment. This study aims to get the best results from the decision support system in Achievement student election in the Mathematics Department of Jember University. Therefore, we need the fuzzy TOPSIS method to avoid and minimize problems and to make multi-criteria decision-making easier. This study's ranking results were obtained from the fuzzy TOPSIS method and standardized assessment method (based on higher education guidelines). From the four candidates who participated in this selection, the two methods give different results in the last two ranks. The fuzzy TOPSIS method ranking shows the results sequentially for candidates B, C, A, and D. In contrast, and the standardized assessment method ranking shows the results sequentially for candidates B, C, D, and A. This difference is caused by the value of the criteria factor and the weight of the candidate criteria, but the fuzzy TOPSIS method is simpler than the standardized assessment method. So that it can be recommended for the next period achievement student election at the department, faculty, or university level.
Antioxidant Assay and Total Flavonoid Determination of Ethanolic Extract of Walnut (Canarium indicum L.) Leaves and Its Fractions
Authors: Lukmanto Lukmanto , Fadhila Nadila Ikhda Ramadhani , Wulandari Lestyo , Puspitasari Endah
Published: February 2023

Antioxidants are compounds that inhibit free radicals. Many plants have antioxidant activity because they contain antioxidant compounds such as flavonoids. This study aimed to evaluate the antioxidant activity, phytochemical contents, total flavonoid content and to establish the relationship of total flavonoid content and antioxidant activity of extract and fractions of walnut (Canarium indicum L.) leaves. Antioxidant activity of ethanolic extract, n-hexane fraction, ethyl acetate fraction, and ethanolic-water fraction of walnut leaves was examined by using the DPPH method and determination of total flavonoid content was determined spectrophotometrically. The results showed that antioxidant activity of ethanolic extract, n-hexane fraction, ethyl acetate fraction, and ethanolic-water fraction based were 25.294 ± 0.055; 175.245 ± 0.4999; 20.135 ± 0.009; and 28.806 ± 0.0424 μg/ml, respectively. The phytochemical content of ethanol extract of walnut leaves are saponins, flavonoids, tannins, and polyphenols. The total flavonoid content of ethanolic extract, n-hexane fraction, ethyl acetate fraction and ethanolic-water fraction were 2.624 ± 0.012; 0.499 ± 0.023; 3.846 ± 0.006; and 1.596 ± 0.006 gram quercetin equivalent/gram extract, respectively. Correlation between antioxidant activity and total flavonoid content revealed that 63.2 % of antioxidant activity was influenced by the presence of flavonoid compounds.
Healing of wounds in diabetic rats treated with Rosa rubiginosa oil
Authors: Nascimento Isadora , Pinheiro Gomes Maria Eduarda Pinheiro Gomes , Gomes Fernandes Naíla Esther , Medeiros Azevedo Ítalo , De Alcântara Oliveira Ramalho Borges Rachel , Cunha Medeiros Aldo
Published: February 2023

PURPOSE: This study aimed to examine if Rosa rubiginosa oil (Rro) influences the healing of skin wounds of diabetic rats. METHODS: Four groups of Wistar rats were used (6 rats/group). Group 1: skin wounds were topically treated with normal saline (NS). Group 2 had skin wounds treated with Rro for 10 days. Diabetes was induced with Streptozotocin (STZ) in groups 3 and 4. Group 3 had the wounds treated with NS. The wounds of groups 4 were treated with Rro. After anesthesia, all rats had skin excisional wounds 0.8 cm diameter. On 10th day, blood glucose and wound tissue cytokines were measured. Histometry of wounds was studied. RESULTS: Glycemia levels of 3 an 4 group rats were >250 mg%. Diabetic and non diabetic rats treated with Rro had wound tissue TNF-α, IL-1β and IL-6 expression lower than in rats receiving NS.  The histological inflammatory score of  Rro treated diabetic rats (19±2.7) was significantly higher than in rats treatment with NS (14±2.5). CONCLUSION: The topical treatment of skin wounds in  diabetic rats with Rosa rubiginosa oil positively influenced the healing.
Bases técnicas da cirurgia das vias biliares
Authors: Medeiros Aldo Cunha , Araújo-Filho Irami , Dantas-Filho Antônio Medeiros
Published: February 2023

RESUMO
A litíase biliar e as complicações dos cálculos biliares são um problema clínico comum. A apresentação clínica pode ser assintomática ou com crises de cólica biliar, que requerem cirurgia eletiva ou de emergência. Os cálculos do ducto biliar estão associados ou não à colelitíase. As colecistectomias são as cirurgias mais comuns realizadas para colelitíase; a presença de cálculos biliares na vesícula é de 10%, mas uma pequena porcentagem dos pacientes desenvolverá cálculos nos ductos biliares. Para evitar as complicações da coledocolitíase, esses cálculos devem ser removidos. A abordagem cirúrgica aberta ao ducto biliar pode ser feita, mas com o advento de técnicas cirúrgicas endoscópicas, radiológicas, as intervenções laparoscópicas avançadas aumentaram em número. Na era da laparoscopia, as abordagens terapêuticas podem ser realizadas em duas sessões ou em uma sessão. A comparação dessas duas abordagens mostrou taxas de sucesso equivalentes, mas o tratamento em uma sessão é caracterizado por menor tempo de internação e mais custo-benefício. O objetivo deste artigo de revisão é fornecer aos leitores estudantes de medicina um resumo geral da litíase biliar associada à presença de cálculos do ducto biliar comum, discutindo a anatomia cirúrgica, os aspectos clínicos e diagnósticos e os possíveis tratamentos.
Diagnostic Problem in a Patient with Tuberculosis Arthritis
Authors: Febrianto Dicky , Awalia Awalia
Published: February 2023

Extra-pulmonary tuberculosis (TB) remains a big public health problem worldwide. Although TB most commonly affects the lungs, any organ or tissue can be involved. TB arthritis is a rare form of extra-pulmonary TB. TB arthritis usually manifests as mild and non-specific arthritis. A 35-year-old male was admitted to the emergency room of Dr. Soetomo General Academic Hospital Surabaya due to pain of left knee since two days prior to admission. His symptom began on previous six months with the swelling of the left knee that gradually worsened so that he had an antalgic gait. Radiological examination of left knee joint showed inflammatory arthritis, accompanied by joint effusion and soft tissue swelling. USG examination of the left knee showed the presence of non-specific left knee arthritis. Patient underwent debridement. Anatomical pathology examination of the tissue obtained at the time of debridement, showed the TB granulomatous inflammation. The Ziehl-Nielson stain of left knee tissue also showed the TB granulomatous inflammation. Patient was then treated with analgesics and anti-TB drugs. The intensive phase of anti-TB therapy was planned to be 2 month, then evaluated and followed by continuation phase for about 7 months. The knee joint is the third most common site of osteoarticular TB after spine and hip. Insidious onset of pain which, in some patients may be present for years, is the usual presentation. The joint is usually warm, and wasting of the thigh muscles is usually marked. Synovial hypertrophy and effusion are present in most patients. The gold standard for diagnosis of TB arthritis is synovial biopsy, with positive results in 80% of cases. It shows caseating granulomas, lymphocytes, and giant cells with caseation, which are characteristics of TB arthritis. Synovial biopsy is generally recommended in any arthritis where clinical evaluation and routine investigations do not give a clear diagnosis.
Diagnosis and Management of Patients with Radiation Colitis
Authors: Rakateja Made Bayu Agastia , Widodo Budi
Published: February 2023

Radiation colitis (Radiation Proctitis or Proctopathy) is a condition in which injury to the rectal mucosa is induced by radiation therapy to the pelvic organs. Radiation colitis is a condition that progresses and is becoming more common and dangerous—usually occurring 6 months to 5 years following regional radiation. This paper presented the diagnosis and management of patients with radiation colitis. There was a patient who had cervical cancer and was hospitalized every 2-3 months because of red blood chapters and weakness. She did chemotherapy and radiation for one year. The patient also received medical therapy, including rectal administration of sucralfate and oral sulfasalazine. Management of patients with radiation colitis is still a problem. There are no definite and consistent guidelines for the treatment of radiation colitis In this patient's case, medical therapy was recently carried out, including rectal administration of sucralfate and oral sulfasalazine. The patient was planning to undergo surgical therapy, but the patient and family refused. It is necessary to think about endoscopic therapy in patients. Argon plasma coagulation (APC) has become the most widely used first-line endoscopic therapy.
Elastase-dependent congenital neutropenia
Authors: Mazur Angelika , Skrzeczynska-Moncznik Joanna , Majewski Pawel , Cichy Joanna
Published: February 2023

Congenital neutropenia, which refers to an inherited deficiency in neutrophils, is a rare pathologic condition that affects approximately 0.0001-0.0009% of the general population. While congenital neutropenia can result from mutations in approximately 30 genes, its leading cause is gain-of-function mutations in the ELANE gene, which encodes the neutrophil granule serine protease, neutrophil elastase. This review focuses on established and novel concepts in the genetic, molecular and cellular mechanisms underlying neutrophil elastase-dependent neutropenia, and discusses possible new avenues for neutropenia research as well as potential novel treatment options that target pathogenic elastase variants.
Tarenna thorelii (Rubiaceae), a new record for Thailand
Authors:   Department of Biological Science, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani 34190, Thailand, Wirot Wirot , Chantaranothai Pranom ,   Department of Biology & Centre of Excellence on Biodiversity (BDC), Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand
Published: February 2023

Tarenna thorelii is reported as a new record for Thailand based on collections from Khon Kaen and Roi Et Provinces. A morphological description based on Thai specimens, distribution, ecological information, conservation status, and short notes on the species as well as an illustration are provided. In addition, a lectotype for T. thorelii is proposed.
Design Space Investigation and Automatized Optimization Utilizing Data Mining and Machine Learning Strategies
Authors:   Professor, Department of Computer Science and Engineering, Mahendra Engineering College, Mahendhirapuri, Namakkal District, Mallasamudram, Tamilnadu, India, Ms M.Manju
Published: February 2023

Recently, the centrality of data mining and machine learning has been featured in expanded application situations. Different data mining and machine learning procedures are regularly used to dissect the colossal measure of information to make more business esteems in top of the line enterprise frameworks. Be that as it may, the headway of advancements has made data mining and machine learning conceivable on low-end frameworks, for example, PCs or installed frameworks. While specialists have proposed amazing work on the management designs of various segments of the framework, the vast majority of the work is based upon the qualities of the framework, which may change every once in a while. This makes it difficult to enhance the framework execution with static, or statically adaptive, framework plans. In the work, propose to install the backings of data mining and machine learning to the design of operating system, to find another, automatized small data analytics framework (ASDAF) to adaptively optimize the framework without utilizing complex algorithms. To approve the proposed thoughts, pick the reserve outline as a contextual analysis, where the substitution of stored substance is consequently controlled by a leader. The chief at that point answers on a data mineworker, which examines the data gathered by the framework screen. The viability of the considered case is confirmed by a progression of analyses, where the outcomes are very promising.
Relevance of Reaction Surface Strategy and Artificial Neural Network Proposal in Representing and Development of Confession-Suction Procedure
Authors:   Professor, Department of Computer Science and Engineering, Mahendra Engineering College, Mahendhirapuri, Namakkal District, Mallasamudram, Tamilnadu, India., Masillamani M.Roberts , Mr C.Vijayakumar ,   Assistant Professor, Department of Computer Science and Engineering, Mahendra Engineering College, Mahendhirapuri, Namakkal District, Mallasamudram, Tamilnadu, India
Published: February 2023

A survey on the use of reaction surface strategy (RSS) and Artificial neural network (ANN) in confession-suction demonstrating and improvement is displayed. The hypothetical foundation of the examined strategies with the application strategy is clarified. The paper portrays most every now and again utilized trial outlines, concerning their constraints and normal applications. The paper additionally exhibits approaches to decide the precision and the hugeness of model fitting for the two strategies depicted in this. Moreover, late references on confession-suction demonstrating and advancement with the utilization of RSS and the ANN approach are appeared. Uncommon consideration was paid to the choice of variables and reactions, and in addition to factual examination of the displaying comes about.
A Survey on Recent Trends and Outcomes in Data Science
Authors:   National Institute of Technology, Arunachal Pradesh, India, Sen Srijon
Published: February 2023

The current era in science, computing, and technology are seeing a lot of movements and revolutions taking place around data science. Data Science is a booming market and lots of research and effort is being made to its outcomes. Now, to make out what exactly data science is then simply a layman would say, the science that revolves around data or the science that deals with gaining insights from data. Data science is only useful when the data is used to answer a specific or a concrete set of question. This research work mainly focuses on the recent data science hot topics and trends that will benefit the community in the long run and what all things that are achievable through data science.
Improve Manufacturing Industry Sentimental Analysis for Machine Learning
Authors:   Research Scholar, Department of Computer Science, Muthurangam Government Arts College, Vellore, Ms Ponniammal M
Published: February 2023

High competitive pressure in the global manufacturing industry makes a successful, successful and sustainable development processes a successful factor. However, analyzes produced by the production control systems are defined by continuous functional improvements defined by large short-rumors. In particular, they do not use data mining to identify hidden patterns in product data. The data mining approach offered by the Advanced Production Analytics Platform is currently based on identification and method based production process optimization. Twitter is a big fast growing micro-blogging social networking platform to express their opinions about the constitution and products game. These ideas are useful for businesses, government and individuals. Therefore, tweets can be used as a valuable source for public opinion. Emotional analysis is a process to automatically identify whether a user-generated speech expresses a positive, negative or neutral point of view of a company.
Study of Second Order(Rivlin-Ericksen) MHD Fluid Flow Due to an Impulsively Started Flat Plate Through Porous Medium
Authors:   Department of Information Techology(Mathematics Section) Shinas College of Technology Shinas, MR Devendra Kumar , MR Rajesh Kumar ,   Bholey Singh, Department of Mathematics SachdevaInstitute of Technology Mathura (U.P.), India, MR R. K. Shrivastava ,   Department Of MathematicsAgra College, Agra (U.P.)India
Published: February 2023

present note is the study of second order Rivlin-Ericksen MHD fluid flow due to impulsively started flat plate through porous medium. The unsteady laminar flow of an elastico-viscous fluid suspended with a uniform distribution of non-conducting dust particles in presence of uniform transverse magnetic field fixed relative to the plate which is applied normal to the flow. Laplace transform is used and analytical results for the velocity of fluid, mixed particles and the skin friction at the plate are obtained. The effect of magnetic field parameter (M), porosity parameter (K) and the mass concentration (l) of the mixed particle on the velocity of both the fluid, the particle and on the skin friction are discussed numerically and displayed graphically
A Study on Biometric Authentication Systems Challenges and Future Trends
Authors:   Assistant Professor, Department of Commerce, K.C.S.Kasi Nadar College of Arts and Science, MR T.Arunmozhi
Published: February 2023

Client confirmation in PC framework is done in view of certain safety efforts like passwords, keys, identityd cards, stick and so forth be that as it may, the abuse and robbery of these safety efforts are likewise expanding because of step by step headway of innovation. This prompted the introduction of biometric security frameworks in which the confirmation of an individual is done in light of a component vector got from physiological as well as behavioral attributes of a person by utilizing biometrics innovation, an individual can be validated in view of his identity rather. With a specific end goal to help tenderfoots picked their examination range or a specific biometric innovation, all the developing biometric advancements and difficulties in every innovation have been talked about in this paper in detail. Future patterns in biometric advancements are likewise talked about.
Low Power Sensor Data Monitoring and Controlling Application Due to IOT Based Distributed Solar Panel
Authors:   Professor, Department of Electronics and Communication Engineering, Mahendra Engineering College (Autonomous), Namakkal, Tamilnadu, India, MR P.V.N.Reddy , MR B.Rajan ,   Associate Professor, Department of Electronics and Communication Engineering, Mahendra Engineering College (Autonomous), Namakkal, Tamilnadu, India, MS S.Mathumitha ,   Assistant Professor, Department of Electronics and Communication Engineering, Mahendra Engineering College (Autonomous), Namakkal, Tamilnadu, India
Published: February 2023

A distributed solar panel control system that allows the user to collect, store, and control and monitor a solar farm situated in remote locations anywhere on the planet. The panel orientation is constantly adjusted according to the sunlight using a servo/stepper motor mechanism aiming to generate maximum power. Each panel is connected to a CAN bus network and comes fitted with sensors that measures parameters such as power, current, voltage, and light intensity and panel orientation. The collected data is transmitted to an IoT gateway using the CAN field bus protocol. The IoT gateway is built with Wi-Fi capability that allows it to get connected to the internet via a Wi-Fi router. The gateway is in constant communication with a cloud platform, where the data gets stored and forwarded to the user. The user can now subscribe to this cloud platform and able to view the collected data, and control and monitor the solar farm in real-time from a remote location from his/her smart phone app.
Survey on Semantic Based Video Hierarchy for Browsing Large Video Repositories
Authors:   Research Scholar, Department of Computer Science, Muthurangam Govt. Arts College, Vellore, MS Sathiyapriya J , MR A.M Saravanan ,   Assistant Professor, Department of Computer Science, Muthurangam Govt. Arts College, Vellore
Published: February 2023

The number of videos exploding on the web is a good challenge in automatic video search. Existing Video search engines, like YouTube, imagine the sorted list of search results. The straightforward list system may be suitable for finding an ad or a music video, although queries cannot be handled with complex header systems, so users create difficulties to find the necessary information. During this event, the best way to a semi-structured array in the nodes that covers all the main headings. Obviously, each question manually changes headlines and thanks for a good range of search titles. By implementing video descriptions on their linguistic information page, we use a prototype-based streamline cluster regime. We will take this information from linguistic information to the complete linguistic information we make by utilizing a sub-ontology conception in our site.
Extracting Emerging Topics Based on User Comments
Authors:   Research Scholar, Department of Computer Science, Muthurangam Govt. Arts College, Vellore, MS J. Jothilakshmi , MS T.K. Ganga ,   Assistant Professor, Department of Computer Science, Muthurangam Govt. Arts College, Vellore
Published: February 2023

The Social website is the place where people can share information about the current events around the world at any time. Social Network Data Analysis Applications have experienced tremendous improvements over the past few years. Due to its straightforwardness, this social network allows data trends to detect current trends, which will have the capacity to affect company global research on the common market research and group program. Unfortunately, by mistake, social network trends mislead people. Trend handling is based entirely on the users text post, including the text and its current combined searches and detection of current trends, but these methods do not know behind compromise and pseudo account users. Therefore, we try to design a safe dialogue approach for handling trends in social networking, which will have a real account of complex manufacturers and small business entities trying to reach fraudulent means and creates compromises and fake accounts. Users made us pay attention to this logic that will lead us to remove the current topic of interest between users to process these contents in this particular behavior.
The Enhancement of Astaxanthin Production Using Medium Cultures Components, Stressors, Nanoparticles, Elicitors, and Gene Engineering in Haematococcus pluvialis
Authors: Garshasbi Hamid
Published: February 2023

Natural astaxanthin is a precious substance obtained from some organisms such as microalgae. This plant has many benefits for humans, so research into its cost-effective and economical production has recently increased. For this purpose, some methods such as the use of different culture media, gene engineering, different stresses, nanoparticles, bio acids, and phytohormones are important. Accordingly, this review study was conducted to demonstrate the effect of the factors mentioned above for the high production of astaxanthin in microalgae, especially Haematococcus pluvialis (H.p).
Effects of Chitosan on the AsA-GSH Cycle of Strawberry Seedlings Under High-temperature and High-light Stress
Authors: Fu Erting , Zhang Yuzheng , Li Huiling , Wang Xiaozhe , Zhang Hanxiao , Xiao Wei , Li Ling , Chen Xiude
Published: February 2023

Chitosan (CTS) is widely used in agriculture as a soil amendment, plant growth regulator and promoter of cold resistance. However, the effects of CTS on strawberry seedlings under the combined stress of high-temperature and high-light are unclear. In this study, Xuelixiang strawberry was used as a test material, and 100 mg·kg-1 CTS solution was sprayed onto the leaves. We measured the chlorophyll content, membrane peroxidation, reactive oxygen species content, antioxidant enzyme content, AsA-GSH cycle activity and other related indicators of strawberry seedling leaves under the combined stress of high-temperature and high-light and found that CTS can increase the contents of antioxidants, increase the contents of osmotic adjustment substances, increase the activity of antioxidant enzymes activity,; remove reactive oxygen species over time, reduce the damage of reactive oxygen species to photosynthetic organs and cell membranes, and improve the photosynthesis efficiency of leaves of strawberry plants under high-temperature and high-light stress, thereby reducing damage to strawberry seedlings caused by high-temperature and high-light.
Overcoming Domain Shift in Neural Networks for Accurate Plant Counting in Aerial Images
Authors: Rodriguez-Vazquez Javier , Fernandez-Cortizas Miguel , Perez-Saura David , Molina Martin , Campoy Pascual
Published: February 2023

This paper presents a novel approach for accurate counting and localization of tropical plants in aerial images that is able to work in new visual domains in which the available data is not labeled. Our approach uses deep learning and domain adaptation, designed to handle domain shift between the training and test data, which is a common challenge in this agricultural applications. This method uses a source dataset with annotated plants and a target dataset without annotations, and adapts a model trained on the source dataset to the target dataset using unsupervised domain alignment and pseudolabeling. The experimental results show the effectiveness of this approach for plant counting in aerial images of pineapples under significative domain shift, achieving a reduction up to 97% in the counting error when compared to the supervised baseline.
Role of Calcium-Activated Potassium Channels in Proliferation, Migration and Invasion of Human Myeloid Leukemia Cells
Authors: Vasileva Valeria Y. , Sudarikova Anastasia V. , Khairullina Zuleikha M. , Chubinskiy-Nadezhdin Vladislav I.
Published: February 2023

Calcium-activated potassium channels (KCa) are the important participants in calcium signaling pathways due to their ability to be activated by increase of the intracellular free calcium concentration. KCa channels are involved in the regulation of various processes in the cells under normal, as well as pathophysiological conditions, including oncotransformation. Previously, with the use of patch-clamp method, we registered the KCa activity in the plasma membrane of human myeloid leukemia K562 cell line. Here, we performed the molecular and functional identification of KCa channels and have uncovered their role in proliferation, migration and invasion of K562 cells. Using a combined approach, we identified the functional activity of SK2, SK3 and IK channels in the plasma membrane of the cells. Selective SK and IK channel inhibitors, apamin and TRAM-34, reduced the proliferative, migratory and invasive capabilities of human myeloid leukemia cells. At the same time, the viability of K562 cells was not affected by KCa channel inhibitors. Our data imply that SK/IK channel inhibitors could be used to slow down the proliferation and spreading of leukemia cells that express functionally active KCa channels in the plasma membrane.