bluuebunny/crossref_metadata_2025 huggingface dataset:
Cumulative Land Subsidence in Populated Asian Coastal Cities
Authors: Takagi Hiroshi , CAO Vu Quynh Anh , Esteban Miguel
Published: August 2023

In contrast to sea-level rise, which is often associated with climatic and environmental changes, land subsidence has largely been overlooked in discussions regarding future adaptation to higher sea water levels. In order to articulate the critical contribution of this phenomenon, this short paper provides a reliable chart that details land subsidence in densely populated East and Southeast Asian coastal cities. The causes of subsidence at these locations are also discussed based on existing literature. Land subsidence was observed to be one or two orders of magnitude faster than sea-level rise caused by an anthropogenic global warming, and can continue unabated unless its root causes are addressed through clear policies at the municipal level. Subsidence is clearly a localized problem, and is thus easily overlooked by regional or national governments. Nevertheless, once subsidence takes place it cannot be reversed, and hence it is crucial to rapidly formulate appropriate countermeasures when it is identified. The examples of these Asian cities demonstrate that, if subsidence is recognized and adequate policies are put in place and implemented, it can be brought under control in a fairly short period of time.
Kawasaki Disease Shock Syndrome and Macrophage Activation Syndrome: A Case Report
Authors: Kim Beom Joon , Kim Danbi , Cho Kyoungsoon , Rhim Jung Woo , Lee Soo-Young , Jeong Dae Chul
Published: August 2023

As a major organ dysfunction, some patients with Kawasaki disease (KD) present with hypotension or shock, known as KD shock syndrome (KDSS). Organ dysfunction is also seen in macrophage activation syndrome (MAS), complicating KD (MAS-KD). Both KDSS and MAS are rare but potentially life-threatening complications of KD that require early recognition. In practice, however, KDSS and MAS can sometimes be overlooked in patients with KD. Here, we describe a 13-year-old boy who presented with prolonged fever, rash, and red eyes, and subsequently developed hypotension. He was diagnosed with KDSS and received inotropic agents and intravenous immunoglobulin (IVIG) treatment. However, his clinical and laboratory features deteriorated, and he met the diagnostic criteria for MAS. KDSS and MAS-KD share many overlapping features in terms of organ dysfunction. A diagnosis of KDSS is made when a patient with KD shows cardiac dysfunction, such as shock. If a KD patient displays multi-organ dysfunction, such as hematologic, hepatic, renal, or neurologic symptoms, they should be diagnosed with MAS-KD. As demonstrated in this case report, some KD patients may present with both cardiac and multi-organ dysfunction and require prompt and proper treatment for both.
Plasma Exchange Treatment in Five Kawasaki Disease Patients Unresponsive to Intravenous Immunoglobulin
Authors: Jun Hyun Ok , Shin Eun-Jeong , Baek Jae Suk , Yu Jeong Jin , Kim Young-Hwue , Ko Jae-Kon
Published: August 2023

The efficacy of high-dose intravenous immunoglobulin (IVIG) treatment for acute-stage Kawasaki disease patients has become widely recognized. However, in the case of refractory Kawasaki disease, alternative treatment should be considered to prevent coronary artery abnormality (CAA). Here, we present several cases of Kawasaki disease in children treated with plasma exchange (PE).

We retrospectively reviewed the medical records of 5 subjects who had been unresponsive to IVIG treatments and treated with PE consecutively.

The fever subsided and the other clinical manifestations were improved after PE in all cases. In two cases, giant coronary artery aneurysms were detected on echocardiographic follow-up study.

PE should be a method with promising efficacy and might be considered in refractory Kawasaki disease patients for whom other treatment options have failed.
Preface to the first issue of SJORANM
Authors: Mosler Frank , Gerd Nöldge
Published: August 2023

Radiology with its increasing numbers of steadily improving diagnostic and minimal invasive therapeutic methods in combination with the skills of diagnostic and therapeutic procedures in nuclear medicine are meanwhile essential tools on a very high level of patient treatment and care in tight cooperation with the clinicians. Our new Journal (SJORANM) wants to give the chance for quick online access to new ideas, new scientific research and results in the diagnostic and therapeutic field of Radiology and Nuclear Medicine.
The Effect of Managerial Ownership, Institutional Ownership, Board of Commissioners, Independent Board of Commissioners, and Board of Directors on Company Value
Authors: Septiani Arilia , Yoewono Harsono
Published: August 2023

The aim of this research is to examine the impacts of managerial ownership, institutional ownership, board of commissioners, independent board of commissioner, and board of director on firm value. The population of this research are companies that included in LQ 45 companies for the period of 2012-2018. By using purposive sampling method, 133 companies were selected as samples. The type of data used in this research is secondary data. Meanwhile, data analysis method that used in this research is descriptive statistics and multiple regression analysis. The T test result of this research indicates that only institutional ownership and independent board of commissioner out of five other variables affects significant positive on firm value. Meanwhile, the F test result of this research indicates that five variables (managerial ownership, institutional ownership, board of commissioners, independent board of commissioner, and board of director) together affect the firm value
The Effect of Profitability on Stock Prices with Capital Structure as a Moderating Variable in Manufacturing Sub-Sector Companies for The Period 2019-2022
Authors: Sianturi Raja Salomo
Published: August 2023

This study aims to determine the effect of profitability on stock prices with capital structure as a moderating variable in manufacturing sub-sector companies for the 2019-2022 period. The population of this study is manufacturing sub-sector companies listed on the Indonesia Stock Exchange for the period 2019 to 2022, totaling 40 companies. Data collection was carried out by purposive sampling. The research data is included in the type of secondary data in the form of financial reports and annual reports during the period 2019-2021. The data was obtained from the Indonesia Stock Exchange website, namely the website www.idx.co.id. The data analysis method used in this study uses multiple linear regression with the help of the SPSS version 24 program. The results of this study indicate that the profitability variable has a positive effect on stock prices. Then the capital structure variable has no effect on stock prices. Furthermore, it was found that the capital structure variable could not moderate the effect of profitability on stock prices in manufacturing sub-sector companies listed on the IDX for the period 2019-2022
Factors affecting senior nursing students’ willingness to palliative care
Authors: Go Hyejin , Kang Hyunju
Published: August 2023

Purpose: This study was conducted to identify the level of senior nursing students’ knowledge about palliative care, meaning of life, and willingness to palliative care and to identify factors affecting their willingness to palliative care.Methods: Data were collected from 192 senior nursing students at six nursing schools in four cities in Korea from December 8, 2022 to January 5, 2023. Descriptive statistics, an independent t-test, Pearson’s correlation, and multiple linear regression test were used to analyze the data.Results: The mean±standard deviation score of knowledge about palliative care and meaning of life were 8.44±2.20 and 146.48±19.32. Factors affecting senior nursing students’ willingness to palliative care were the knowledge about palliative care (β=.18, p=.005), meaning of life (β=.36, p<.001), and motivation for admission into a nursing school based on aptitude and interest (β=.16, p=.020).Conclusion: It is necessary to develop a nursing education program for enhancing knowledge about palliative care and meaning of life to prepare the palliative care competency of nursing students.
Factors Affecting the Growth of Low Birth Weight Babies
Authors: Suyami Suyami , Lusmilasari Lely , Istiono Wahyudi
Published: August 2023

Birth weight is one of the determinants of a child's physical growth and future brain development. However, babies with low birth weight (LBW) are at risk of death and other health problems. The purpose of this literature review is to systematically summarize research that analyzes the factors that influence the growth of low birth weight babies. The method used was a literature review using the PRISMA Protocol, with inclusion criteria, namely full text and original research, the research subjects were babies born with low birth weight (<2500g), articles in Indonesian and English, published in the last 5 years (2017-2022). The results showed that there are several factors that influence the growth of infants with a history of low birth weight such as gender (male), lower gestational age, postnatal health problems, nutritional intake, such as exclusive breastfeeding or enteral feeding, and maternal parenting practices such as Kangaroo Mother Care (KMC). Exclusive breastfeeding and maternal parenting practices (Kangaroo Mother Care) have an impact on increasing growth so it is good to apply especially for mothers who have low-birthweight babies to catch up with age-appropriate growth.
Reverse Evidentiary Analysis in Article 12 B Paragraph (1) A and B of Law Number 20 of 2001 Amendments to Law Number 31 of 1999 Concerning The Eradication of Corruption
Authors: Akbar Delvin , Gunadi Ariawan
Published: August 2023

The purpose of this study is to analyze the philosophical basis of the reverse proof system for future Gratification corruption crimes and the formulation of norms for the reverse proof system for future Gratification corruption crimes. The research method used in this study is normative juridical with qualitative descriptive data analysis techniques. The results of the study are the philosophical basis of the reverse proof system for the crime of graft corruption related to bribery Article 12 B, namely that both the public prosecutor and the defendant are obliged to prove but the public prosecutor alone proves the gift received by the recipient of the gratuity while the defendant proves that the gratuity is not a bribe, has nothing to do with position and does not conflict with their duties or obligations. The construction of legal substance, which directs the formulation of reverse evidentiary norms with an emphasis on legislative policies according to the 2003 CAC as a characteristic of the combination of the hukum umum and hukum sipil legal systems as a legal system.
Analysis of the Settlement of South China Sea Disputes by the International Arbitration Tribunal
Authors: Heniasy Vivi , Rannu Delycia Anwar , Putri Audrey Bilbina
Published: August 2023

The settlement of South China Sea disputes by the International Arbitration Board is a complex challenge. The South China Sea is a strategic area disputed by several countries in Southeast Asia. International Arbitration Bodies play an important role in handling these disputes. Arbitration proceedings began in 2013 and a decision was announced in 2016. Although the decree is legally binding, its implementation still faces political and diplomatic challenges. Cooperation between the countries involved is necessary to achieve an effective solution.
Effect of Steeping Green Tea (Camellia Sinensis L.) Against IL6 and IL 10 Levels in Rats Exposed to Cigarette Smoke
Authors: Ayu Pratiwi Surya , Sarosa Hadi , Trisnadi Setyo
Published: August 2023

The prevalence of smokers in Indonesia is more than 25% of the total population. Cigarette smoke contains numerous free radicals that trigger the formation and increase of Reactive Oxygen Species (ROS) within the body, leading to inflammation and cytokine production. Green tea contains catechins known for their potent antioxidant properties. This study aims to assess the levels of Interleukin 6 and Interleukin 10 in rats exposed to cigarette smoke. The research method used was the post-test only control group design, involving 24 male Wistar rats divided into 4 groups: Normal group (N), Control - (Cigarette Smoke), Control + (Cigarette Smoke + 1.44 mg/day Vitamin E), P. (Cigarette Smoke + 3.6 ml Green Tea Infusion). Interleukin 6 and Interleukin 10 levels were measured after 14 days of treatment. Data were analyzed using One Way Anova. The mean IL-6 level in the Control (-) group was the highest (141.75±6.24 pg/ml), while the Sham group had the lowest (73.58 ± 4.57 pg/ml) IL-6 level. One Way Anova results showed a p-value of <0.001 for both IL-6 and IL-10 levels, indicating a significant difference among the four groups. Post Hoc LSD test results indicated that the IL-6 levels in the K(+) group were relatively similar to the IL-6 levels in the P group (p=0.172). Post Hoc LSD test results for IL-10 levels between the two groups were all significant, with a p-value of <0.001. The administration of green tea infusion was shown to affect the Interleukin 6 levels, while green tea infusion did not have a significant impact on Interleukin 10 levels in white rats exposed to cigarette smoke.
Operator Performance Analysis Using Overall Labor Effectiveness Method with Root Cause Analysis Approach
Authors: Rahmadiani Pratiwi , Kusrini Elisa
Published: August 2023

The growth of the manufacturing sector in Indonesia has slowed down due to the increase in COVID-19 cases, which has led to a decrease in the production volume of companies. This impact needs to be reassessed by each company, and one way to address it is by continuously improving company productivity. PT X is one of the companies in the manufacturing sector that has a program to continuously enhance its productivity, with its production result being pianos. This study focuses on the performance of operators in a specific production area that has consistently not met the company's productivity target over a period. The objective is to determine the effectiveness of the operators in that area using the Overall Labor Effectiveness (OLE) method. Subsequently, the obtained OLE results will be analyzed using the Root Cause Analysis (RCA) method, and improvement proposals will be provided, supported by the House of Quality (HOQ) method and previous literature. The research results indicate issues in one of the OLE variables, namely the performance ratio. Root cause analysis was conducted to identify the underlying issues, assisted by brainstorming tools, the 5-why method, and a fishbone diagram. This analysis revealed three main problems. Furthermore, two design proposals were formulated using the HOQ framework, and an additional proposal was based on previous research findings.
Social Innovation of PT. Pertamina EP Pendopo Field for Conservation the Protected Orchid Plants in Selangit Village, Musi Rawas Regency
Authors: Samudin W Mohammad Nur , Suharyadi Suharyadi , Rosadi Hengky , Maulidda Renny , Husni Nyayu Latifah , Handayani Ade Silvia , Rezza Muhammad
Published: August 2023

A rescue program was made to save orchid plants in Selangit Village by initiating and involving the community. This activity began in 2017 and now, more than 250 species of orchid plants have been successfully rescued. The decline of some species of orchid plants are due to many factors, such as the endemic nature, forest fire, illegal logging, and illegal sales by collector can be an accelerator of their extinction.  This activity can be a trigger to increase insight and ideas for the government and local community in developing natural areas. Working together between PT. Pertamina EP Pendopo Field and South Sumatera Natural Resources Conservation Center to build the Selangit Greenhouse aims to save orchid plants and can be an education facility for educators and learners. Next, this program advised to development of tourist village destinations by increasing training and promotion activities of flora tourism activities, and can be sustainable social activity in rescuing orchids and rare plants in Selangit village.
Legal sanctions against members of the National Police who Abusing Narcotics at Bengkulu Police Station
Authors: Pratiwi Anggi , Neltje Saly Jeane
Published: August 2023

Today narcotics crime is seen as a crime that is an enemy of humanity, therefore countries in the world including Indonesia continue to struggle to eradicate this crime. The issues raised in writing this thesis are Law Enforcement Against Members of the Police Who Abuse Narcotics and Psychotropics, how to regulate and Criminal Sanctions against the National Police who commit Narcotics Crimes, and how to apply criminal sanctions and a code of ethics to the National Police as perpetrators of Narcotics Crimes. The research method used in this paper is the normative juridical research approach. The normative juridical method in which this research examines the literature or secondary data which includes books and legal norms contained in statutory regulations, legal principles, legal rules and legal systematics and also examines the provisions of statutory regulations and legal materials others. From this research it can be concluded that 1) The process of law enforcement against members of the police who are caught in cases of criminal acts of narcotics abuse is in accordance with the applicable laws and regulations, in which in the process all people are equal in the eyes of the law, even in law enforcement the suspects is a member of the police, the sentence can be more severe. This is because the suspect is a law enforcement officer who should carry out a position order to fight narcotics, but the suspect is involved in a criminal case of drug abuse. 2) The process of enforcing the police professional code of ethics against members of the police who are caught in criminal cases of narcotics abuse in fact has not been carried out properly where the police do not immediately take firm action against members who are caught in criminal cases of narcotics abuse, as if the police are still protecting their members and are considered after their members have tried in general court and found guilty of committing a narcotic crime.
The Effect of Foot Massage Relaxation Techniques To Reduce Pain Level In Patients With Ventilator In ICU Cengkareng Hospital In 2022
Authors: Lasria Parhusip Helena , Astrid Maria , Hary Susilo Wilhelmus
Published: August 2023

Pain usualy experienced by patients on ventilator in the ICU. Efforts to reduce pain with foot massage done independently on the patient. Foot massage safe complementary therapy, providing  relaxing effect, feeling comfortable and reducing pain. This study used quasi experiment research design with pre and post test control group design. The total sample of 40 respondents was divided into an intervention group 30 respondents were given foot massage once a day for 2 consecutive days, the control group was 10 respondents given analgesic therapy for 2 consecutive days. Post test pain scores 30 minutes after getting treatment on first and second days.  Results showed that majority of the age group 46-55 years 30%, majority male 57%, 65% were suctioned, and body position changes 82%, there was difference in pre-test (p = 0.001) and post-test (p=0.007) the intervention group, there was difference in the level of pain after foot massage in the intervention group and the administration of analgesics the control group (p=0.000), there was effect of suctioning mucus (p=0.003), there was effect of changes in body position (p=0.008). This means that foot massage has effect reducing pain levels in patients. This study recommends the need for further research and foot massage one of independent nurse interventions in nursing care for patients with ventilatory pain.
Home-garden Ethnobotanical Studi on Stunting Cases in The Kalipuro Settlement, Banyuwangi
Authors: Wahono Budi , Hakim Luchman , Kartikaningsih Hartati
Published: August 2023

This study aims to describe and map the differences in ethnobotany of residential gardens with cases of stunting and without stunting. This research is both quantitative and qualitative. Data collection was carried out using semi-structured interviews and field observations at 20 points of the squared plot of vegetation observations which also became a source of information. The data obtained was then analyzed for vegetation using the Shannon-Wiener index method and the use value of species. The results showed that there were differences in preferences for the use of plants in local community settlements with cases of stunting and non-stunting. Utilization of plants with the highest UVs were in settlements with cases of stunting, namely Zingiber officinale, Pandanus amaryllifolius and Amorphophallus muelleri, while in the yards without stunting cases were Actinocarpus commansi Blanco, Magnolia acuminata (L.) , Moringa olefira Lam, and Artocarpus altilis (Parkison ex F.A.Zorn) Fosberg. Communities in settlements without stunting cases consume intensely sources of food from their garden plots, while people in settlements with stunting cases do not. In particular, Moringa plants are only found in residential yard gardens without stunting and are not found in settlements with stunting cases.
Development Model of Traditional Ritual Festivalization as Cultural Tourism Attraction in Padang Panjang City, West Sumatra
Authors: Harrisa Siti Ivadhea , Kristanto Yohanes , Sendra I Made , Ridho Rahmad Oscar
Published: August 2023

Traditional rituals were part of the daily life of the Minangkabau and Mentawai indigenous peoples in the past. Since the arrival of Islam, the understanding that has developed in Minangkabau society is "adat basandi syarak, syarak basandi Kitabullah", which means that adat refers to Shari'a, Shari'a refers to the Koran. Halal branding has become a framework for developing tourism in West Sumatra which has resulted in tensions with the indigenous Mentawai people who do not adhere to Islam. The Festival Ritual Nagari raised in this thesis raises both rituals from the culture of the Minangkabau and Mentawai indigenous peoples. This thesis discusses the festivalization of traditional rituals carried out in the city of Padang Panjang, West Sumatra. This research aims to enrich cultural tourism attractions that are inclusive of Mentawai traditional culture so as to achieve the common goal of increasing visitors to West Sumatra. This research was conducted in a qualitative descriptive manner with cultural thematic analysis methods. In-depth interviews were conducted with stakeholders involved in developing the traditional ritual festival in Padang Panjang. The results of this study indicate that the development of traditional rituals as a cultural tourism attraction requires a development model so that the ritual festivals carried out can be sustainable. This study shows that the collaboration of stakeholders greatly influences the continuity of traditional ritual festivals. In addition to the development model, an event management flow chart for the Festival Ritual Nagari 2 and the 2023-2026 Nagari Festival Ritual event calendar were also found. The active collaboration of all stakeholders is suggested so that the Festival Ritual Nagari can be carried out continuously in the future. The establishment of regulations regarding the festival of traditional rituals is needed because it does not only function as a cultural tourism attraction but also cultural diplomacy.
Telehealth vs. In-Person Documentation - the Same, only Different
Authors: Bell Jennifer
Published: August 2023

This article provides clarification according to documentation best practices as of July 29, 2020 under the temporary coding and billing flexibilities for outpatient telehealth visits. Few changes are expected until October, when HHS Secretary Azar revisits the need to renew or end the current public health emergency.
Applying Quality Improvement Methods to Decrease Bowel Obstruction Complications After Total Joint Arthroplasty
Authors: Adenikinju Abidemi , Meneses Michelle , Arbuah Nancy , Latorre Melissa , Hutzler Lorraine , Lavin Patricia , Lajam Claudette
Published: August 2023

BACKGROUND:

Though infrequent, bowel obstruction complications after total joint arthroplasty (TJA) can cause significant patient morbidity and mortality. There are few reports of prevention protocols for these complications in current literature. The purposes of this study were to (1) create a protocol to prevent bowel obstruction complications in TJA patients using the Plan-Do-Study-Act (PDSA) quality improvement model as well as (2) assess the effect of the protocol on the incidence of such complications.

METHODS:

The protocol was created by a multidisciplinary task force at a single specialty orthopedic hospital. Gastrointestinal complications were monitored after implementation of the protocol. The protocol was continually evaluated for problems and modifications were made as necessary.

RESULTS:

The protocol was implemented in May 2018. From that time until the end of the year, there was a 31.9% decrease in cases of ileus and no cases of bowel obstruction or perforation were observed.

CONCLUSION:

Bowel obstruction complications after TJA adversely affect patient outcomes. This study describes a standardized protocol created via the PDSA method of quality improvement that aims to prevent these complications in this patient population through early identification and intervention. Given the growing demand of TJA, future research should focus on further standardization of postoperative care in efforts to improve patient outcomes and reduce healthcare costs.
The Development of an Orthopaedic Prone Positioning Tool in the COVID-19 Era
Authors: Rahman Omar , Zbeda Robert M. , Romeo Anthony A.
Published: August 2023

Although the COVID-19 pandemic has created hurdles for the practice of orthopedic surgery, it has also provided an opportunity for reflection, innovation, and creative thinking. Orthopedic surgeons utilize clinical knowledge and technical skillsets along with a strong understanding of medical devices to provide effective care for patients. However, these skillsets can also lateralize to other sectors of medicine outside of the surgical theater. From the authors’ experiences at a tertiary orthopedic center, they review the process of repurposing a patient positioning tool in the operating room toward the treatment of intubated COVID-19 patients and discuss the lessons learned.
The Effect of a Natural Oral Nutritional supplement on the Level of Intra-Articular Inflammatory Mediators in Patients with Osteoarthritis of the Knee
Authors: Sharkey Peter , Shah Zubin , Gross Michael , Meade Thomas , Davidoff Scott , Shohat Noam , Parvizi Javad
Published: August 2023

Objective: To determine the clinical efficacy of a novel combination of natural agents with potential anti-inflammatory properties in patients with knee osteoarthritis.

Design: A prospective, randomized, double-blind, multicenter study.

Methods: Subjects with symptomatic knee osteoarthritis were randomized to one of two groups; Synogesic® (Group A) or placebo (Group B). Synogesic is a proprietary blend of Turmeric Extract, Ginger Root Extract, Boswellia Serrata Extract, Vitamin C, Vitamin D and Rutin. Patients were evaluated at baseline and 12 weeks after enrollment. Patient reported outcome measures (PROM) included Visual Analog Scale (VAS) for pain, Western Ontario and McMaster Universities Arthritis Index (WOMAC) and Knee injury and Osteoarthritis Outcome Score (KOOS). Synovial fluid samples were obtained at baseline and at 12 weeks and sent for measurement of various inflammatory markers.

Results: 43 patients (22 in Group A and 21 in Group B) completed the study. In Group A, VAS for pain improved by 46.8% (P<0.001), WOMAC by 23.4% (P=0.006), KOOS for pain and ADL by 19.8% and 14.9% respectively (P=0.008 and P=0.002). In Group B, there was no significant improvement in any of the PROM assessed. Synovial fluid inflammatory markers increased by 6.2% in Group A and 54.6% in Group B (P=0.02). Of the 41 pro-inflammatory markers examined, 26 (63.4%) decreased in Group A, while only 13 (31.7%) decreased in Group B (P = 0.008).

Conclusion: In this study, the novel natural anti-inflammatory product reduced pain and improved function, likely through reduction of pro-inflammatory cytokines in synovial fluid in patients with knee osteoarthritis.
High Value Tibial Nail Utilization Improves Cost Without Compromising Outcomes: Experience at a Level II Trauma Center
Authors: Flinn Daniel C , Gurnea Taylor P , Gonzalez Miguel A , Dobrich Jordan , Shul Craig P , Althausen Peter L
Published: August 2023

Introduction

In today’s opportunistic healthcare climate, value based care has moved to the forefront of cost containment. With respect to orthopaedic trauma, it has become increasingly important to factor cost into the treatment of an often underinsured patient population. As patents expire on many commonly used trauma implants, high value alternatives represent an excellent opportunity for trauma surgeons to provide value-based care so long as it does not compromise outcomes. The objective of this study was to appraise the clinical and economic impact of the use of high quality, low-cost tibial nails in the treatment of tibial shaft fractures.

Methods

Two hundred patients treated with high value tibial nail implants were compared to two hundred patients treated with conventional implants at a busy community level II trauma center between January 2011 and December 2019. Operative records were reviewed to identify intraoperative complications, operative time, and estimated blood loss. Cases of infection, malunion, nonunion, or need for repeat surgery were recorded. Hospital financial records were analyzed to determine implant cost.

Results

There was no appreciable difference in age, sex, diabetes, smoking, or American Society of Anesthesiologist (ASA) physical status score between the high value and conventional groups. A significant difference in operative time was observed. No differences were observed in intraoperative or postoperative complications. There was no significant difference found in return to the operating room or interlocking screw removal. Analysis found an average of $735 per case in implant savings. This represented a 38% reduction in implant cost with an overall realization of $147,000 in savings across the study period.

Conclusion

The use of high value tibial nails at our institution resulted in significantly reduced implant expenditures with equivalent radiographic and clinical outcomes. Based on this data, the use of high value tibial nail implants has potential to markedly reduce operative costs without compromising patient care as long as quality products are utilized.
Interprosthetic Femur Fractures: Systematic Review
Authors: Golub Ivan , Ng Mitchell K , Vakharia Rushabh M , Kang Kevin K , Cannada Lisa K
Published: August 2023

Objectives

Interprosthetic femur fractures (IFF) present unique challenges to orthopaedic surgeons due to the preexisting implants in place, oftentimes advanced age and poor bone quality. Through the development of specific implants and improvement of fixation principles, management of this rare—yet growing—fracture pattern has progressed in recent decades to improve patient outcomes. This study’s aim was to identify patient-related outcomes after undergoing ORIF of interprosthetic femur fractures, including time to union, change in pre-operative ambulatory status, malunion/nonunion, surgical site infections, and revisions.

Data sources

A systematic review of published literature was conducted on Pubmed/MEDLINE and Cochrane Library databases for English language papers published with 12 studies meeting inclusion/exclusion criteria.

Study selection

Studies providing quantitative data comparing time to union, change in ambulatory status, surgical site infections, malunion/nonunion, revisions, and one-year mortality were used in the analysis. Studies lacking quantitative data were excluded.

Data extraction

12 studies were included in this systematic review and graded by MINOR to identify potential biases. The aforementioned patient outcomes were calculated as mean values, ranges, and percentages.

Data synthesis

Time to union averaged 20.2 (range 6-28) weeks with roughly 18% of patients experiencing a decline in pre-operative ambulatory status. It was found 1.3% of patients experienced surgical site infections that were treated successfully either operatively or nonoperatively. Malunions and nonunions occurred in 1.63% and 6.12% of cases, respectively. Revisions were necessary in 12.6% of cases due to malunion, nonunion, and hardware failure. The one-year mortality rate was 12.8%.

Conclusion

Our review demonstrates that interprosthetic femur fractures continue to pose significant challenges in their treatment to both patients and orthopaedic surgeons. With the expected continued growth in the number of primary total hip and total knee arthroplasty performed annually, the incidence of interprosthetic femur fractures will continue to rise. Full femur spanning locked plating is currently the standard of care in fracture patterns with stable prostheses.

Level of Evidence

Therapeutic Level III
Value Creation vs. Value Capture in Orthopedics
Authors: Kurtz William
Published: August 2023

This article will discuss commoditization, market forces, value capture, and value creation. Using these terms, we are going to evaluate orthopedic decisions and discuss how these decisions might affect the future of orthopedics and digital therapeutic (DTx) MSK companies.
Hip fractures: Does Timing Really Matter?
Authors: Suk Michael
Published: August 2023

This is the lecture, on this topic, given by Michael Suk, MD, at the Orthopaedic Value Based Care Meeting 2022.
Remplissage: is it all that?
Authors: Sethi Paul
Published: August 2023

An editorial concerning the value of the remplissage procedure.
Application Of Inventory And Service Transactions On Web-Based Cv Medan Teknik using the Agile Kanban Method
Authors: Wahyuni Sri , Wadly Fachrid
Published: August 2023

This study discusses the application of website-based goods supply and service transactions using the agile kanban method on cv. Engineering Field. The Agile Kanban method facilitates efficient workflow management and visualizes inventory management progress and transactions in real-time. Kanban boards are used to track tasks, identify bottlenecks and ensure smooth collaboration between team members. The manual journal book recording system has many constraints and weaknesses so that inventory data processing is needed where the availability of goods will be better organized by using a supportive and adequate information system and computer equipment. Inventory application on CV. Website-based Medan Teknik is an activity system consisting of goods entry data and goods inventory data that reports all transactions in and out of goods from per day, per month, to per year. Programs that are built based on websites use the PHP programming language and MySQL database to make it easier for users, namely admins, cashiers and leaders to input data, access reports with an internet connection that can be accessed anytime and anywhere
ANALISIS FITUR APLIKASI INTERNET MOVIE DATABASE (IMDB) DENGAN METODE CUSTOMER KNOWLEDEGE MANAGEMENT(CKM)
Authors: Nathanael Audi , Nantu Gregorius , Kristianto Ryan Putranda
Published: August 2023

This study aims to analyze the features of the Internet Movie Database (IMDb) application using the Customer Knowledge Management (CKM) method. CKM is an approach to collecting, managing and leveraging customer knowledge to support decision making and improve customer relationships. In the context of IMDb, CKM can assist in understanding user needs and preferences, providing a better experience, and increasing user satisfaction. This study uses a feature analysis approach to evaluate key features in IMDb applications and determine how these features contribute to management. customer knowledge. Features that will be analyzed include complete information about movies and TV series, cast lists, directors, producers, ratings, user reviews, search features, recommendations, and community features. The method used in this study is CKM, which involves collecting data from different sources, such as IMDb application documentation, analysis of application components, and user feedback. These data are then analyzed and evaluated to determine the effectiveness of IMDb features in supporting customer knowledge management. The results of this analysis are expected to provide useful insights for IMDb application developers to improve user experience, improve existing features, and identify areas for improvement. potential. In addition, this research can also contribute to the understanding of the application of CKM in the context of the entertainment industry and the importance of customer knowledge management in achieving higher user satisfaction.
RANCANG BANGUN WEBSITE INFORMASI DAN PEMBAYARAN SPP SEKOLAH MENGGUNAKAN PHP DAN BOOTSTRAP (STUDI KASUS SMA PGRI 1 JAKARTA)
Authors: Febrian Reza Putra , Widiyaningsih Wiwied , Lailasari Mita
Published: August 2023

Penelitian ini bertujuan untuk merancang dan membangun website informasi dan pembayaran SPP sekolah yang  berisi informasi mengenai SMA PGRI 1 Jakarta dan fasilitas pembayaran SPP yang dilakukan secara online. Hal ini dilatar belakangi oleh adanya kekurangan dari sistem yang berjalan di SMA PGRI 1 Jakarta mengenai cara pembayaran SPP yang masih dilakukan secara manual dan  informasi mengenai sekolah yang masih kurang. Dengan kemajuan teknologi internet, untuk informasi mengenai SMA PGRI 1 Jakarta dan pembayaran SPP dapat dibuat agar bisa dilakukan secara online dengan menggunakan website sehingga siswa maupun orang tua dapat melakukan pembayaran dengan lebih mudah. Penelitian ini akan membahas rancang bangun website informasi dan pembayaran SPP sekolah dengan studi kasus pada SMA PGRI 1 Jakarta dengan metode penelitian menggunakan metode Waterfall dan website tersebut dibuat menggunakan PHP dan Bootstrap.
APLIKASI CHATBOT ONLINE UNTUK PEMESANAN TIKET BIOSKOP MENGGUNAKAN NATURAL LANGUAGE PROCESSING
Authors: Erlina  , Pratama Simamora Rizky Gerry , Rasjid Hasma , Basyah Baby Lolita
Published: August 2023

Dalam era digital seperti saat ini, kebutuhan,kemudahan dan kenyamanan dalam berbagai aspek kehidupan semakin meningkat. Salah satunya adalah pembelian tiket bioskop Untuk memenuhi kebutuhan tersebut, banyak aplikasi  yang bermunculan dengan berbagai fitur dan layanan yang memudahkan pengguna dalam memesan tiket. Namun, dengan semakin banyaknya aplikasi pembelian tiket yang tersedia, pengguna seringkali mengalami kesulitan dalam mencari informasi yang dibutuhkan. chatbot pada aplikasi pembelian tiket bioskop dapat menjadi solusi yang tepat untuk membantu pengguna dalam menyelesaikan berbagai tugas dan memperoleh informasi yang mereka butuhkan secara cepat dan mudah. Sebagian masyarakat masih melakukan pembelian tiket bioskop secara langsung di tempat, permasalahan yang dapat terjadi adalah konsumen harus antri dan memerlukan waktu yang lama. Untuk itu Natural language processing (NLP) diterapkan ke dalam chatbot supaya bisa berkomunikasi seperti halnya manusia. Selain chatting dengan bot, aplikasi ini dibangun agar memudahkan masyarakat dalam melakukan pemesanan tiket bioskop. Aplikasi ini dibangun menggunakan Java Script dan ReactJS, serta dirancang menggunakan diagram UML. Metode pada penelitian ini adalah SDLC waterfall. Sistem ini dapat digunakan untuk memesan tiket bioskop melalui chatting dengan bot secara online dan real time.
INFORMASI PENENTUAN TEMPAT MAGANG SISWA SMK DENGAN METODE SIMPLE ADDITIVE WEIGHTING (SAW)
Authors: Tri hartanti Ninik , Dwi Irawan Ridwan
Published: August 2023

Sistem pendidikan di Indonesia, khususnya Sekolah Menengah Kejuruan (SMK) merupakan sekolah yang dalam pola pembelajarannya lebih banyak prosentase memberikan keterampilan atau praktek yang bertujuan untuk membekali para lulusannya sehingga memiliki keterampilan yang bisa diunggulkan terutama di dunia industri atau usaha. Pembekalan tersebut dilaksanakan dengan mengadakan kerjasama diantara pihak sekolah dengan pihak industri atau usaha, dengan melaksanakan praktek kerja (magang). Pihak sekolah akan memberikan beberapa pilihan tempat untuk siswa melaksanakan magang. Tujuan penelitian ini adalah membantu pihak sekolah dan siswa dalam menentukan tempat magang, dengan harapan siswa dapat melaksanakan magang dengan merasa aman, nyaman, tenang dan memperolah hasil kinerja yang memuaskan. Sistem informasi untuk menentukan tempat magang para siswa ini menerapkan salah satu metode perhitungan dalam data mining, yaitu Simple Additive Weighting (SAW). Sistem akan memudahkan dalam proses penentuan tempat magang, dengan beberapa kriteria yaitu jarak tempat magang, kesesuaian dengan jurusan, ada tidaknya tempat kos untuk sementara, kebersihan tempat magang, dan luas tempat magang.
Removal of an intraosseous hemangioma of the frontal bone through an anterior hairline incision: a case report
Authors: Kim Myung-Good , Ryu Jeong-Ho , Lee Dong Min , Park Tae-Seo , Choi Ji-An , Lee Keun-Cheol , Han Song-Hee
Published: August 2023

An intraosseous hemangioma of the frontal bone is typically removed via a coronal incision. This procedure, while effective, can be lengthy and may result in complications such as a prominent scar and hair loss. An alternative approach involves a direct incision in the forehead, which leaves a less noticeable scar and allows a quicker recovery. However, in this specific case, the patient declined both coronal surgery and surgery through a direct forehead incision due to cosmetic concerns. Therefore, we proposed an anterior hairline incision. A 35-year-old woman presented with a firm, non-mobile, palpable mass on her right forehead. Preoperative non-contrast computed tomography revealed a heterogeneous osteolytic lesion. We performed an excisional biopsy through the anterior hairline. Postoperative non-contrast computed tomography was conducted 2 and 6 months after surgery. The wound was clean and free of complications, and there was no local recurrence. Partial resection can reduce scarring for patients who are concerned about cosmetic outcomes. However, the potential for recurrence remains a significant concern. We present this case of an anterior hairline incision for a hemangioma located in the forehead, evaluated using serial computed tomography for both preoperative and postoperative imaging.
Erratum
Authors: Naidu C
Published: August 2023

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Introducing the South African Rare Diseases Access Initiative
Authors: Malherbe H
Published: August 2023

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Multi-objective Optimization with QoS Constraints in WSNs
Authors: Azizi Tarek
Published: August 2023

One of the most active research areas in wireless sensor networks are coverage and improving QoS parameters. This paper focuses on the deployment optimization problem of WSNs dedicated to the monitoring area of interest. In this kind of networks, nodes are classified into two classes: Sensor Nodes (SNs) deployed within the area of interest for targets coverage and Relay Nodes (RNs) which relay sensed messages generated by the sensor nodes up to the sink node. In this study, we propose a Multi-Objective Throughput and Lifetime Optimization (MOThLO) which maximizes simultaneously the throughput and lifetime of sensor nodes, while ensuring network energy, latency and sensors lifetime. In order to evaluate the performance of our proposal, we have conducted many tests.
Combined microRNA-141 Rescue and MAPK1 Silencing as Putative Strategy to Support Chemotherapy in Translational Stage towards Metastatic Castration-resistant Prostate Cancer – an In Vitro Model Study
Authors: Tsvetankova Radostina , Tsvetkova Ilka , Apostolova Albena , Hayrabedyan Soren , Todorova Krassimira
Published: August 2023

Tumourigenesis is associated with disruption of cell differentiation, proliferation, migration, and abnormal DNA methylation. Deregulation of transcription factors MAPK1 and NF-κB and other post modification factors play an important role in these processes. Using AR-positive and AR-negative cell line models (LNCaP-p53+/+ and PC3-p53-/-), we found MAPK1 siRNA silencing as potentially productive approach to decrease castration-resistant cell line invasiveness, but not sufficient to abrogate anti-apoptotic, pro-inflammatory by NF-κB signalling, and so we combined this approach with miR-141 rescue (mimic) and inhibition to further modulate autophagy signalling and eventually block MAPK1/NF-κB/ROS pathways. We found miR-141 rescue to upregulate AR and NF-κB inductor ACT1 and to promote total DNA demethylation, in LNCaP, but not in PC3 cells, suggesting microRNA-141 rescue as putative enhancer to MAPK1 blockade in conjunction to pro-apoptotic chemotherapy, but only in transitional towards castration-resistance stages.
Two-Point Discrimination in Feet with Ankle Sprains
Authors: Olcar Hacı ali , Miniksar Ökkeş H. , Güngör Berna , Kuru Tolgahan , Kapukaya Enes E. , Aydın Davut , Korkmaz Murat
Published: August 2023

Background: This study aimed to compare two-point discrimination in feet with ankle sprains and feet without ankle problems, and to determine whether there was a change in the two-point discrimination values in ankle sprains.

Methods: A total of 108 people were included in the study. These subjects were aged between 18 and 40 years and visited the Medical Faculty of Yozgat Bozok University for various reasons in July and September of 2022. These people were divided into two groups: subjects with an ankle sprain and subjects with no ankle problems. Two-point discrimination values measured in millimeters were recorded for both groups using a caliper (esthesiometer) used in six regions of 216 feet. The two-point discrimination threshold values of the feet were compared statistically according to feet with ankle sprains and feet without ankle problems, and in right and left feet.

Results: The study determined that the two-point discrimination threshold values measured at the first toe tip, heel, third plantar metatarsal head, medial malleolus, and lateral malleolus in subjects with an ankle sprain was higher than in subjects with no ankle problems. When comparing both feet of the subjects with an ankle sprain, the two-point discrimination threshold value in the heel of the foot with an ankle sprain was higher than in the heel of the foot without ankle problems.

Conclusions: The two-point discrimination threshold value was higher in subjects with an ankle sprain than in subjects with no ankle problems. The data suggest that the two-point discrimination threshold may be higher in people with an ankle sprain. Further studies are needed to better understand the two-point discrimination threshold in ankle sprains.
Deficiency of IQCH causes male infertility in humans and mice
Authors: Ruan Tiechao , Zhou Ruixi , Yang Yihong , Guo Junchen , Jiang Chuan , Wang Xiang , Shen Gan , Dai Siyu , Chen Suren , Shen Ying
Published: August 2023

IQ motif-containing proteins can be recognized by calmodulin (CaM) and are essential for many biological processes. However, the role of IQ motif-containing proteins in spermatogenesis is largely unknown. In this study, we identified a loss-of-function mutation in the novel gene IQ motif-containing H (IQCH) in a Chinese family with male infertility characterized by a cracked flagellar axoneme and abnormal mitochondrial structure. To verify the function of IQCH, Iqch knockout (KO) mice were generated via CRISPR-Cas9 technology. As expected, the Iqch KO male mice exhibited impaired fertility, which was related to deficient acrosome activity and abnormal structures of the axoneme and mitochondria, mirroring the patient phenotypes. Mechanistically, IQCH can bind to CaM and subsequently regulate the expression of RNA-binding proteins (especially HNRPAB), which are indispensable for spermatogenesis. Overall, this study revealed the function of IQCH, expanded the role of IQ motif-containing proteins in reproductive processes, and provided important guidance for genetic counseling and genetic diagnosis of male infertility.