bluuebunny/crossref_metadata_2025 huggingface dataset:
Logistics and Legitimation: Religious Pluralism in the Bà Tower, Nha Trang City, Vietnam
Authors: Cầm Hoàng , Hiền Nguyễn Thị
Published: February 2024

Abstract: Today, in the space of Poh Nagar Stupa in Nha Trang City, Khánh Hòa province, Vietnam, there exists a diverse abundance of religious practices. For many people from Bóng village and the Vietnamese communities who work as seafarers around the area, the deity located in the Stupa is the holy Mother Thiên Y A Na Diễn Ngọc Phi, a local goddess. For other Việt, especially the members of the Patronage Association of the Bà Stupa, the Goddess that they worship in the main Stupa is the embodiment of Nam Hải Guan Yin Bodhisattva. In the consciousness and practices of the Chăm people, especially the Chăm groups from Ninh Thuận and Bình Thuận provinces, the supreme deity in the Stupa is their Poh Nagar Goddess of Land. In tandem with this diversity of religious beliefs is a symbiosis of different ritual practices. The Chăm people practice the ritual in the traditional way of worshiping the Poh Nagar Mother Goddess of the Land. The Việt people of the Patronage Association practice Buddhist rituals. The ritual practice of the Bóng villagers follows procedures for rituals dedicated to the tutelary God of a Việt traditional village festival. Viewed from the practitioner's perspective, the co- existence of the diversity of religious practices at the Stupa reveals an ongoing need for compromise and sometimes contestation.
Impact of interstitial lung disease on left ventricular myocardial function
Authors: Stumpf Max Jonathan , Wirtz Marina Michaela Luise , Fleddermann Max Fabian , Biener Leonie , Weinhold Leonie , Weber Marcel , Schaefer Christian Alexander , Nickenig Georg , Skowasch Dirk , Pizarro Carmen
Published: February 2024

Background

Interstitial lung disease (ILD) comprises a wide variety of pulmonary parenchymal disorders within which progressive fibrosing ILD (PF-ILD) constitutes a phenotypic subset. By use of speckle tracking-based strain analysis we aimed to evaluate the degree of left ventricular (LV) dysfunction in progressive vs. non-progressive fibrosing ILD (non-PF-ILD).

Methods

A total of 99 ILD patients (mean age 63.7 ± 13.5 years, 37.4% female), composed of 50 PF-ILD and 49 non-PF-ILD patients, and 33 controls were prospectively enrolled and underwent conventional and speckle tracking echocardiography. Additional laboratory and pulmonary function testing, as well as six-minute walk test were performed.

Results

As compared to the non-PF-ILD cohort, PF-ILD patients exhibited a significantly impaired forced vital capacity (2.4 ± 1.0l vs. 3.1 ± 0.9l, p = 0.002), diffusion capacity for carbon monoxide (DLCO, 25.6 ± 16.3% predicted vs. 43.6 ± 16.67% predicted, p <0.001) and exercise capacity response as measured by the six-minute walk test distance (268.1 ± 178.2m vs. 432.6 ± 94.2m, p <0.001). Contrary to conventional echocardiographic LV parameters, both regional and global longitudinal LV strain measurements were significantly altered in ILD patients as compared to controls. No differences in LV strain were found between both patient groups. Significant correlations were observed between global longitudinal strain, on the one hand, and systemic inflammation markers, total lung capacity (TLC) and DLCO, on the other hand (high-sensitivity C-reactive protein: Pearson´s r = -0.30, p< 0.001; interleukin-6: Pearson´s r = -0.26, p = 0.007; TLC % predicted: Pearson´s r = 0.22, p = 0.02; DLCO % predicted: Pearson´s r = 0.21, p = 0.02).

Conclusions

ILD is accompanied by LV dysfunction. LV functionality inversely correlates with the severity of the restrictive ventilatory defect and inflammation marker levels. These observations support the assumption of persistent low-grade systemic inflammation that may link systemic cardiovascular function to ILD status.
Phospholipase A2 activity is required for immune defense of European (Apis mellifera) and Asian (Apis cerana) honeybees against American foulbrood pathogen, Paenibacillus larvae
Authors: Jin Gahyeon , Hrithik Md Tafim Hossain , Mandal Eeshita , Kil Eui-Joon , Jung Chuleui , Kim Yonggyun
Published: February 2024

Honeybees require an efficient immune system to defend against microbial pathogens. The American foulbrood pathogen, Paenibacillus larvae, is lethal to honeybees and one of the main causes of colony collapse. This study investigated the immune responses of Apis mellifera and Apis cerana honeybees against the bacterial pathogen P. larvae. Both species of honeybee larvae exhibited significant mortality even at 102 103 cfu/mL of P. larvae by diet-feeding, although A. mellifera appeared to be more tolerant to the bacterial pathogen than A. cerana. Upon bacterial infection, the two honeybee species expressed both cellular and humoral immune responses. Hemocytes of both species exhibited characteristic spreading behaviors, accompanied by cytoskeletal extension along with F-actin growth, and formed nodules. Larvae of both species also expressed an antimicrobial peptide called apolipophorin III (ApoLpIII) in response to bacterial infection. However, these immune responses were significantly suppressed by a specific inhibitor to phospholipase A2 (PLA2). Each honeybee genome encodes four PLA2 genes (PLA2A ~ PLA2D), representing four orthologous combinations between the two species. In response to P. larvae infection, both species significantly up-regulated PLA2 enzyme activities and the expression of all four PLA2 genes. To determine the roles of the four PLA2s in the immune responses, RNA interference (RNAi) was performed by injecting gene-specific double stranded RNAs (dsRNAs). All four RNAi treatments significantly suppressed the immune responses, and specific inhibition of the two secretory PLA2s (PLA2A and PLA2B) potently suppressed nodule formation and ApoLpIII expression. These results demonstrate the cellular and humoral immune responses of A. mellifera and A. cerana against P. larvae. This study suggests that eicosanoids play a crucial role in mediating common immune responses in two closely related honeybees.
Perinatal transmission of Lyme disease: A qualitative study investigating the research priorities of patients with Lyme disease in pregnancy
Authors: Omar Abeer , Grenier Lindsay N. , Marquez Olivia , Faber Sue , Darling Elizabeth K.
Published: February 2024

Introduction

Lyme disease is one of the most prevalent vector-borne disease in North America, yet its implications during pregnancy are poorly understood. Our knowledge of perinatal transmission of Lyme disease is limited due to the lack of robust epidemiological studies and longitudinal follow-up.

Objectives

This study aimed to understand the research priorities of people who have experienced Lyme disease in pregnancy and the feasibility of recruiting this population for future studies on perinatal transmission of Lyme disease. We also sought to understand the barriers and enablers to participating in research on perinatal transmission of Lyme disease.

Methods

We conducted a qualitative study using focus groups and interviews with people who had experienced Lyme disease during pregnancy. English speaking participants were recruited through an online survey. There was no geographic restriction on participation. The focus groups and the interview were recorded and transcribed. Data were analyzed using interpretive content analysis.

Results

Twenty people participated in four semi-structured focus groups and one semi-structured individual interview. The majority of participants were from North America. Participants’ research priorities fell into five categories: transmission, testing, treatment, disease presentation, and education. All study participants expressed interest in future participation in research on Lyme disease in pregnancy and highlighted barriers and enablers to participation that could be addressed to facilitate future study recruitment.

Conclusion

The research priorities identified in this research would be well addressed through prospective research. People who experience Lyme disease in pregnancy are invested in continued research into perinatal transmission of Lyme disease.
MalnutritiOn assessment with biOelectrical impedaNce analysis in gastRic cancer patIentS undergoing multimodaltrEatment (MOONRISE)—Study protocol for a single-arm multicenter cross-sectional longitudinal study
Authors: Pelc Zuzanna , Sędłak Katarzyna , Mlak Radosław , Chawrylak Katarzyna , Mielniczek Katarzyna , Leśniewska Magdalena , Skórzewska Magdalena , Kwietniewska Magdalena , Paśnik Iwona , Gęca Katarzyna , van der Sluis Pieter , Banasiewicz Tomasz , Pędziwiatr Michał , Polkowski Wojciech P. , Pawlik Timothy M. , Małecka-Massalska Teresa , Rawicz-Pruszyński Karol
Published: February 2024

European data suggests that over 30% of gastric cancer (GC) patients are diagnosed with sarcopenia before surgery, while unintentional weight loss occurs in approximately 30% of patients following gastrectomy. Preoperative sarcopenia significantly increases the risk of major postoperative complications, and preoperative body weight loss remains a superior predictor of outcome and an independent prognostic factor for overall survival (OS) in patients with GC. A standardized approach of nutritional risk screening of GC patients is yet to be established. Therefore, the MOONRISE study aims to prospectively analyze the changes in nutritional status and body composition at each stage of multimodal treatment among GC patients from five Western expert centers. Specifically, we seek to assess the association between nutritional status and body composition on tumor response following neoadjuvant chemotherapy (NAC). Secondary outcomes of the study are treatment toxicity, postoperative complications, quality of life (QoL), and OS. Patients with locally advanced gastric adenocarcinoma scheduled for multimodal treatment will be included in the study. Four consecutive nutritional status assessments will be performed throughout the treatment. The following study was registered in ClinicalTrials.gov (Identifier: NCT05723718) and will be conducted in accordance with the STROBE statement. The anticipated duration of the study is 12–24 months, depending on the recruitment status. Results of this study will reveal whether nutritional status and body composition assessment based on BIA will become a validated and objective tool to support clinical decisions in GC patients undergoing multimodal treatment.
Acute stress negatively impacts on-task behavior and lecture comprehension
Authors: Morava Anisa , Shirzad Ali , Van Riesen James , Elshawish Nader , Ahn Joshua , Prapavessis Harry
Published: February 2024

Acute stress has been shown to disrupt cognitive and learning processes. The present study examined the effects of acute stress on mind wandering during a lecture and subsequent lecture comprehension in young adults. Forty participants were randomized to acute stress induction via the Trier Social Stress Test or rest prior to watching a twenty-minute video lecture with embedded mind wandering probes, followed by a lecture comprehension assessment. Stress responses were assessed via heart rate, blood pressure, salivary cortisol, and state anxiety. Individuals exposed to acute stress endorsed greater mind wandering at the first checkpoint and lower lecture comprehension scores. Moreover, state anxiety post stress was positively associated with mind wandering at the first and second checkpoint and negatively associated with lecture comprehension. Only mind wandering at the third checkpoint was negatively correlated with overall lecture comprehension. Taken together, these data suggest that acute stress, mind wandering, and lecture comprehension are inextricably linked.
Comparison of immunological and molecular methods for laboratory diagnosis of ocular toxoplasmosis in blood, serum and tears in Brazil
Authors: Ramos Raissa Cristina Ferreira , Barbosa Alynne da Silva , Aleixo Ana Luisa Quintella do Couto , Arruda Igor Falco , Amendoeira Maria Regina Reis
Published: February 2024

Ocular toxoplasmosis (OT) is caused by protozoan T. gondii. Ophthalmological examination is considered the gold standard for OT diagnosis, and laboratory tests are used for diagnostic confirmation. However, these tests can present different results, which change depending on their basis, on sample type and on patients’ clinical alteration. Thus, the aim of the present study is to assess immunodiagnostic and molecular techniques applied in blood, serum and tear fluid to diagnose T. gondii infection in patients seen at an Ophthalmology Clinic. In total, 160 patients were included in the study, 40 of them had OT with active lesions (G1); 40 had OT with healed lesions (G2), 40 had non-toxoplasmic uveitis (G3) and 40 had no ocular alterations (G4). Serum samples were subjected to Immunoenzymatic Assay (ELISA) and to Indirect Immunofluorescence Reaction (IFAT) to search for anti-T. gondii IgM and IgG. Tear fluid samples were analyzed through ELISA for IgA research. All blood and tear fluid samples were subjected to conventional polymerase chain reaction (cPCR) and in a Nested PCR model for T. gondii DNA amplification with targets B1, GRA7 and REP 529. IgG and IgM anti-T. gondii was detected in serum samples from 106 and 15 patients, respectively, when combining ELISA and IFAT results. Anti-T.gondii IgA antibodies were detected in 9.2% of the tear material. Nested PCR with GRA7 target showed higher positivity in blood samples (24.4%); Nested PCR with B1 target showed a higher frequency of positivity in tears (15%). Biological samples of patients with active lesions showed the highest positivity frequencies in all immunodiagnostic assays, as well as in most PCR models. The present results highlighted the need of associating techniques with different fundamentals to confirm OT diagnosis. Furthermore, further tear fluid analyses should be performed to validate this biological material as lesser invasive alternative for the more accurate OT diagnosis.
Magnetocaloric effect modeling of dysprosium-transition metal based intermetallic alloys for magnetic refrigeration application using hybrid genetic algorithm based support vector regression intelligent method
Authors: Ibn Shamsah Sami M.
Published: February 2024

Intermetallic alloy containing rare earth dysprosium ions with the associated unfilled 4f shell electrons and sub-lattice of 3d-transition metal, results into fascinating magnetic properties which are useful for green refrigeration technological application. Magnetocaloric effect remains the fundamental principle upon which magnetic refrigeration technology is based while this cooling technology has advantages of cost effectiveness, high efficiency and environmental friendliness as compared with the existing conventional gas compression systems. Maximum magnetic entropy change (which controls the hugeness of magnetocaloric effect) of intermetallic alloy Dy-T-X (where T = transition metal and X = any other metal or nonmetal) is modeled in this work using hybrid genetic algorithm based support vector regression (GSVR) computational intelligent method with applied magnetic field, ionic concentration and ionic radii descriptors. The developed GSVR-G model with kernel Gaussian function outperforms GSVR-P model with polynomial function with improvement of 85.23%, 78.82% and 78.67% on the basis of the computed correlation coefficient (CC), mean absolute error (MAE) and root mean square error (RMSE) on testing sample, respectively. The developed model further investigates the influence of applied external magnetic field on magnetocaloric effect of DyCuAl intermetallic alloy. The developed models in this work circumvent experimental challenges of magnetocaloric effect determination while the recorded precision of the developed model further opens doors for possible exploration of these intermetallic compounds for addressing environmental challenges associated with the present system of cooling.
Denaturalizing cruelty: Maixabel Lasa, victim and peacemaker, in Zubiak (Jon Sistiaga and Alfonso Cortés-Cavanillas 2019) and Maixabel (Iciar Bollaín 2021)
Authors: Martín Annabel
Published: February 2024

Within Basque society there exists a special subset of human beings, painful I–You binomials, forever linked through blood, by the lethal terrorist gun. Fortunately, today victims face a much more hospitable society, but it is still a moment rife with contradiction. One part of Basque society finds it difficult to imagine a shared collective memory that will faithfully reflect the excesses committed by Euskadi ta Askatasuna (ETA) and the Spanish state regarding human rights abuses. These misgivings are easily understood when some still debate the humanity of the victims themselves. Another part of Basque (and Spanish) society questions the political intent of restorative practices, of those experiences that bring victims and victimizers together within the framework of restorative justice, a political stance that, like in the first case, highlights the need to humanize the Other in the name of peace. The creative world of the arts, more specifically, the films studied in this article, move in a different direction and beg the question: if the processes of restorative justice are uniquely designed to be experienced in a triangulated scenario – one shared by victim, victimizer, and the dead – what might these conversations offer a society in need of better models of co-existence when put on the screen? Can art mediate?
¿Conoces a tu Buyer Persona? Identifica a tu cliente para mejorar tu estrategia de Inbound Marketing
Authors: Romero Montero Andrés , Sellers-Rubio Ricardo , Cely Alvarez Adriana María
Published: February 2024

Este artículo analiza cómo diferentes modelos de alojamiento utilizan la metodología del buyer persona para optimizar estrategias de inbound marketing. En particular, se busca conocer cómo los alojamientos turísticos definen el buyer persona, qué herramientas y técnicas utilizan para definirlo y qué relación se establece entre la definición del buyer persona y las estrategias y acciones a nivel de mercado. El estudio aplicó una metodología cualitativa de análisis inductivo que permitió analizar los casos en profundidad. Para ello, se realizaron ocho entrevistas semiestructuradas a responsables de marketing digital de campings, apartamentos turísticos, cadenas hoteleras y hoteles independientes. Los resultados obtenidos corroboran que la metodología del buyer persona potencia un conocimiento profundo del cliente y facilita estrategias efectivas para cada modelo de alojamiento. Las recomendaciones invitan a profundizar en su análisis y a aprovechar el potencial de esta metodología.
Determining factors for tourist satisfaction in inland destinations: Impact on the depopulation problem
Authors: Arranz Val Pablo , Puche Regaliza Julio César , Antón Maraña Paula , Aparicio Castillo Santiago
Published: February 2024

Depopulation is currently a major problem in Spain, especially in inland areas. Tourism can help alleviate this problem. Therefore, competitive advantages must be enhanced by developing a capable and sustainable tourism model that can lead to the desired level of development in a given geographical area. A powerful decision-making and diagnostic tool was created for the tourism industry in the Burgos Province, Spain to identify the key factors in tourist satisfaction, which can influence the decision to recommend and revisit a destination. This study presents this tool and a theoretical model of tourism satisfaction. The findings emphasize the significance of the perception that tourists have of the quality of a destination's goods and services and its impact on satisfaction. Enhancing tourist satisfaction can have important implications for improving tourism management and, consequently, addressing the depopulation problem.
Tristes guerras. Distopía y empatía en el turismo de memoria traumática
Authors: Navajas Corral Óscar
Published: February 2024

Desde que en la década de los años noventa del pasado siglo se creara el neologismo de «turismo oscuro» a la práctica de los turistas por visitar espacios patrimoniales relacionados con el dolor, la pena, la muerte o el trauma, este no ha dejado de crecer. La oferta y la demanda aumentan cada año en este subsector; lo que ha multiplicado las investigaciones de los especialistas, así como los debates sobre las fronteras éticas de su práctica. La realidad, es que algunos de los destinos no corresponden con únicamente con hechos de nuestro pasado lejano y/o reciente, sino con conflictos bélicos actuales, donde la tragedia y el trauma son parte de la vida diaria de los habitantes de un territorio. En este artículo se presenta el estado del sector turístico que denominamos de memoria traumática; sus impactos sociales, culturales y económicos; las carencias de las narrativas en su puesta en valor que están llevando en algunos casos a generar una oferta distópica; y nuestra aportación como posible solución desde el trabajo de la empatía histórica.
Reseña del libro: Destinos Post Turísticos: genealogía de la construcción territorial de nueve destinos (post) turísticos argentinos
Authors: Otero Adriana María
Published: February 2024

Reseña del libro: González, Rodrigo C. Destinos Post Turísticos: genealogía de la construcción territorial de nueve destinos (post) turísticos argentinos / Rodrigo C. González. - 1a ed. - San Luis: Nueva Editorial Universitaria - U.N.S.L., 2023. Libro digital, PDF, ISBN 978-987-733-375-6
The Hopewell Cosmic Airburst Event: A review of the empirical evidence
Authors: Tankersley Kenneth Barnett , Meyers Stephen D. , Meyers Stephanie A.
Published: February 2024

Abundance peaks in microscopic materials, including meltglass, microspherules, Ni, Ir, and Pt have been found in Native American Hopewell-age cultural strata. This discovery includes micrometeorites (possibly pallasites) recovered from heavily burned strata in two Hopewell villages. This evidence suggests that a prehistoric cosmic airburst/impact event occurred in the Ohio River valley. The peaks in these exotic materials only occur within a dark, charcoal-rich burn layer containing a wide range of Hopewell artifacts, and they are not found above or below the layer. Transgenerational oral histories and possibly two unique airburst-shaped Hopewell earthworks at or near the epicenter suggest that Native Americans living in the Ohio River valley may have been eyewitnesses to the impact event. AMS radiocarbon ages (n = 15) obtained directly from cultural and geological contexts indicate that the airburst/impact event occurred within a 70-year window from 1640-1570 cal BP. The Hopewell culture existed from ~2100-1500 cal BP and suffered a severe decline beginning ~1650 cal BP, suggesting that the proposed impact event occurred near the end of that span. After the proposed event, the hallmarks of the Hopewell culture, such as monumental landscape architecture, the largest geometric earthen enclosures in the world, intricate hilltop water management systems, massive burial mounds, and extensive ceremonial centers, were no longer constructed in the area impacted by the airburst. We propose that this cosmic airburst/impact event catalyzed the economic and sociopolitical decline and reorganization of the Hopewell cultural complex in the Ohio River valley for villages directly affected by the proposed airburst.
Innovations in Teaching History: Eighteenth-Century Studies in Higher Education
Authors: McCormack Matthew
Published: February 2024

An essential teaching companion offering practical strategies for enhancing learning for all teachers of history in higher education. The study of the eighteenth century has been a growth area in university research and teaching in recent decades. Although widely taught in history departments, the eighteenth century also presents challenges, including new students’ unfamiliarity with the period, the theoretical and interdisciplinary nature of the critical writings, and extensive online source material requiring digital skills for its evaluation. Focusing on pedagogical innovation and current developments in the discipline, this collection of essays reflects on how we teach the history of the long eighteenth century, exploring current subfields such as histories of material culture, the senses, gender, crime and empire. It presents practical case studies showcasing how novel teaching methods can be employed in the classroom that promote active learning and invite students to think critically about the nature of their discipline. Methods covered include decolonising the curriculum, digital history, transferable skills, engaging with objects, working in non-classroom settings and multisensory approaches. Grounded in real academic practice, this is a valuable guide for all history educators, whether specialising in the eighteenth century or beyond.
Regional inequalities among state universities in Chile: Perspectives on centralization and neoliberal development
Authors: Fleet Nicolas , Flores Arturo , Montiel Braulio , Palma Álvaro
Published: February 2024

Drawing on perspectives from top state-regional universities’ authorities (known as rectors) and public statistics on higher education, we discuss the sources of regional inequality in the Chilean university system. While there is scarce research on regional inequality for Chilean higher education, it is a well-recognized concern within global debates. In this study, the testimonies of rectors link perceptions of regional inequality to the historic, political, and managerial dimensions that have determined their institutions’ development. As the problem of regional inequality stems from a tradition of political centralization, the neoliberal transformations, imposed since 1981, were singled out by the rectors for institutionalizing patterns of marketization that reinforced “inequalities of origin” for state-regional universities. Since the 2000s, trends of massification, regulation, and student protests reshaped higher education, leading to sectorial reform in 2018. However, competitive disadvantages are seen to continue to hinder the public role of state-regional universities. Institutional development strategies emerged, under the direction of rectors, to compensate for such inequalities, differentiating between winners and losers of neoliberal higher education. This article characterizes the modes of reproduction and overcoming of regional inequalities among state universities under neoliberal policy.
Laju Pertumbuhan dan Kandungan Fikosianin Spirulina sp. pada Konsentrasi Urea yang Berbeda
Authors: Arrosyd Muhammad Azam , Santosa Gunawan Widi , Endrawati Hadi
Published: February 2024

Spirulina sp. adalah mikroorganisme autotrof dari kelas Cyanophyta yang berbentuk filamen terpilin menyerupai spiral (helix), dan merupakan salah satu sumber pangan dan pakan yang potensial. Faktor yang mempengaruhi pertumbuhan serta kandungan pigmen salah satunya adalah nutrien. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi urea yang berbeda terhadap laju pertumbuhan dan kandungan pigmen fikosianin pada Spirulina sp. Metode penelitian yang digunakan adalah eksperimental laboratoris dengan menggunakan Rancangan Acak Lengkap. Mikroalga Spirulina sp dikultur dengan 4 taraf perlakuan yang berbeda yaitu pemberian urea 90 mg/L, 105 mg/L, 120 mg/L, 135 mg/L dan 1ml/L pupuk Walne sebagai kontrol dengan tiga kali ulangan. Hasil penelitian menunjukkan laju pertumbuhan tertinggi pada perlakuan kontrol walne sebesar 0,697 dan terendah pada perlakuan 90 mg/L sebesar 0,447. Kandungan pigmen fikosianin tertinggi terdapat pada perlakuan kontrol walne sebesar 0,272 mg/mL disusul dengan perlakuan 120 mg/L, 105 mg/L dan 135 mg/L dengan masing-masing 0,095 mg/mL; 0,068 mg/mL dan 0,046 mg/mL. Berdasarkan hasil penelitian diproleh hasil bahwa perbedaan konsentrasi urea memiliki pengaruh terhadap laju pertumbuhan Spirulina sp. P< 0.05, namun tidak memberikan pengaruh terhadap kandungan pigmen fikosianin mikroalga Spirulina sp. P> 0.05.   Spirulina sp. is an autotrophic microorganism from the Cyanophyta class which is in the form of a spiral-like twisted filament (helix), and is a potential source of food and feed. One of the factors that affect growth and pigment content is nutrients. This study aims to determine the effect of different urea concentrations on the growth rate and content of phycocyanin pigments in Spirulina sp. The research method used was experimental laboratory using the Completely Randomized Design. Spirulina sp microalgae were cultured with 4 different levels of treatment, namely urea 90 mg/L, 105 mg/L, 120 mg/L, 135 mg/L, and 1ml/L Walne fertilizer as a control with three replications. The results showed that the highest growth rate was in the Walne control of 0.697 and the lowest was in the 90 mg/L treatment of 0.447. The highest phycocyanin pigment content was found in the Walne control of 0.272 mg/mL, followed by the 120 mg/L, 105 mg/L, and 135 mg/L treatments with 0.095 mg/mL, 0.068 mg/mL and 0.046 mg/mL,respectively. Based on the results of the study, it was found that the difference in urea concentration had effect to the growth rate of Spirulina sp.(P < 0.05), but did not have an effect on the phycocyanin content of microalgae Spirulina sp. P≥ 0.05.
Parameter Pertumbuhan Kepiting Bakau (Scylla paramamosain Estampador, 1950) di Perairan Pantai Utara Rembang, Jawa Tengah
Authors: Adriyani Alvita , Saputra Suradi Wijaya , Sabdaningsih Aninditia
Published: February 2024

Kepiting bakau merupakan salah satu komoditas perikanan penting di Indonesia sejak awal tahun 1980-an. Kepiting bakau termasuk dalam famili Portunidae yang merupakan salah satu komoditas perikanan dibudidayakan. Tujuan dari penelitian untuk mengetahui nisbah kelamin kepiting bakau, struktur ukuran panjang karapas kepiting bakau, hubungan panjang karapas dan berat kepiting bakau dan parameter pertumbuhan kepiting bakau. Penelitian ini dilakukan pada bulan September 2022 - Februari 2023 di Perairan Pantai Utara Rembang, Jawa Tengah. Metode yang digunakan dalam penelitian ini adalah metode survei. Pengambilan sampel menggunakan metode sistematik random sampling. Data primer yang dikumpulkan yaitu panjang karapas (CL) dan bobot kepiting bakau. Analisis data menggunakan software Microsoft Excel dan FISAT II. Hasil penelitian didapatkan yaitu spesies kepiting bakau Scylla paramamosain, perbandingan nisbah kelamin kepiting bakau jantan dan betina yaitu 1,12:1. Total sampel sebanyak 167 ekor ukuran panjang karapas kepiting bakau berkisar 41-95 mm. Pola pertumbuhan kepiting bakau jantan dan betina yaitu allometrik negatif artinya tergolong ke dalam pipih atau dalam kondisi tidak gemuk. Koefisien pertumbuhan (k) kepiting bakau jantan dan betina yaitu pertumbuhan panjang karapas kepiting bakau betina lebih cepat dibandingkan dengan kepiting bakau jantan.
Perpetuum Mobile. Dzienniki przemieszczania się po nie-miejscach Blixy Bargelda
Authors: Burzyńska Anna R.
Published: February 2024

Tematem artykułu są strategie life writing niemieckiego kompozytora, muzyka i performera Blixy Bargelda, który od lat 90. dokumentuje swoje życie jako artysty uczestniczącego w kolejnych tournées. Doświadczenie przemieszczania się pomiędzy kolejnymi identycznymi, bezosobowymi nie-miejscami (wg terminologii Marca Augé), takimi jak hotele i lotniska, okazuje się przeciwieństwem idei podróżowania. W konsekwencji dziennik podróży Bargelda przyjmuje nietypowe formy: od serii fotografii ukazujących hotelowe łazienki (serialbathroomdummyrun), przez eksperymentalną prozę (Europa kreuzweise. Eine Litanei), po osadzone w tradycji muzyki konkretnej kompozycje (album Perpetuum Mobile).
Quasi-dzienniki jako laboratorium eksperymentu – przypadek Andrzeja Falkiewicza
Authors: Kołodziej Dorota
Published: February 2024

Artykuł ma na celu interpretację trzech nieprzeczytanych dotychczas wspólnie utworów Andrzeja Falkiewicza (Fragmenty o polskiej literaturze, Takim ściegiem, Ta chwila). Publikacje te zostają określone mianem quasi-dzienników które pozwala uchwycić prywatny charakter tych zapisków oraz ich eksperymentalną. Definicja dziennika przyjęta od Philippe’a Lejeune’a pozwala powiązać charakterystyczną dla tej formy wariacyjną, muzyczną budowę z zasadą powtórzenia charakterystyczną dla autora Polskiego kosmosu, koncepcja zaś autobiograficznej postawy wyzwania Małgorzaty Czermińskiej dostrzec, że Falkiewicz wciąga czytelnika w pewnego rodzaju grę. Jednak bliższa analiza retorycznej warstwy tekstów, a także eksperymentów związanych z wykorzystaniem komputera do nadawania znaczenia warstwie typograficzno-wizualnej nakazuje zrewidowanie wcześniejszych założeń i pozwala spojrzeć na twórczość Falkiewicza, zwłaszcza na Ledwie mrok, z nowej perspektywy, pokazując, w jaki sposób autor, wbrew deklaracjom świadczącym o potrzebie bycia przeczytanym, wymazuje czytelnika z tekstów.
Glaciology and glacial geomorphology, by Wilfried Hagg, 2022
Authors: Rachlewicz Grzegorz
Published: February 2024

Review:Glaciology and glacial geomorphology, by Wilfried Hagg, 2022. Springer, Berlin/Heidelberg, 186 pages. Hardcover: price €90.94, e-book: price €71.68; ISBN 978-3-662-64713-4.
Thanks to the journal's reviewers
Authors: Editors of Geologos
Published: February 2024

Not provided.
Management of wounds in diabetes by administering allicin and quercetin in emulsion form as wound medicine in diabetic rat models
Authors: Nusantoro Agik Priyo , Kuntaman Kuntaman , Perdanakusuma David Sontani
Published: February 2024

Wounds in diabetes is a complex problem that requires effective treatment at a high cost. Adjuvant therapy from natural bioactive elements can be an alternative to overcome problems in diabetic wound healing disorders. Allicin and quercetin are natural bioactive substances contained in several fruit or vegetable plants that have various pharmacological effects. The purpose of this study was to determine the effect of allicin and quercetin in emulsion form as wound medicine in helping the wound healing process. Diabetic wistar rats with wounds on their backs measuring 1 × 1 cm were divided into four treatment groups which were given wound medicine once a day for seven days according to their distribution. The wound healing process was evaluated on the third and seventh day. Data were observed and analyzed using appropriate statistical tools. Measurement of wound healing indicators was carried out by examining wound contraction and histopathological examination showing that the treatment group given the allicin and quercetin formula experienced an improvement compared to the treatment group without allicin and quercetin. Allicin and quercetin increase the percentage of wound contraction, increase the density of blood vessels and the epithelialization process in the wound so that the wound healing process becomes faster. In conclusion, allicin and quercetin can be effective adjuvant therapies in helping wound healing in diabetes. Wound medication in the form of an emulsion is an effective choice, because it can maintain the stability of the allicin and quercetin content and can make the wound environment moist.
Szabályalkotó tevékenység a Jászkun kerület községeiben (1702–1745) és a székely falvakban
Authors: Bánkiné Molnár Erzsébet
Published: February 2024

Legislative Activity in the Municipalities of the Jászkun District (1702–1745) and in the Szekler Villages The study reviews the emergence of community legal customs, known as the Jászkun redemption, established before 1745 within the administrative and juridical unit of the Jászkun district, based on archival documents. The author compares the methods of creating local laws in the Jászkun district with the statute-making processes in the Szekler villages. She identifies the common origins of local legislation in both areas and delves into the examination of the societal impact of local laws and statutes.
A gyermekágy időszaka a jogszokások tükrében
Authors: Deáky Zita
Published: February 2024

The puerperal period in the context of legal customs The postnatal period is part of an archaic system of rites of purity and impurity. The separative, protective elements and rules of conducts became a community norm and regulatory system in the Christian culture on the basis of the Old Testament religious law (MOSES III 12: 1- 8), and were incorporated into the legal folk customs and, rom the end of the 19th century, into the laws protecting the workers and the factory workers.
„Lovagrendi családjog” A középkori k resztes lovagrend, mint „nagycsalád”
Authors: Falusi Orsolya
Published: February 2024

"Knightly Family Law" - the medieval Crusader Order as "Extended Family" From secular knights, the "bellatores", to the order of the Crusaders, there was a long road in the first centuries of the Middle Ages. The organization of the hospitaller crusader order functioned like an "extended family", headed by the Grand Master as the exerciser of paternal authority. The purpose of the paper is to present the functions similar to the "extended family".
Adalékok a család büntetőjogi védelmének történetéhez
Authors: Mezey Barna
Published: February 2024

Additional notes to the history of criminal law protection of the family Judicial practice at the turn of the 18th and 19th centuries prosecuted sexual acts that directly disturbed the peace of family and marriage with consistency despite the lack of legal codification in Hungarian law, the absence of legal definitions and the deficit of a national and coherent regulation. Moreover, it also provided protection against behaviour detrimental to the morality of society and indirectly or potentially disruptive to family life. Due to the lack of consecrated articles, the slowly commencing penal codification was rather affected by changing moral perceptions, thus, could have only little impact on the practice of traditional law-making until the mid-19th century.
Mongol jogszokások: házasság és család*
Authors: Zeneemyadar Batbayar
Published: February 2024

Mongolian Legal Customs: Marriage and Familyln Mongolian and nomadic societies - where the role of the family as the primary and fundamentalcommunity of society was decisive - wedding customs were carefully regulated, and the role of legalcustoms was extremely important in this. ln the nomadic society, the wedding was not only about therelationship between two people, but about the alliance and union of two families and two tribes. The role of customary norms in nomadic law is also proven by the fact that the customs andtraditions of the wedding feast have been followedwithout any changes for centuries, apart from minor changes.
Elephant Tusks and Natural Selection
Authors: Kidd Aaron E. , De Jesús Daniel J. , Poor Sarah V.
Published: February 2024

Evolutionary theory is foundational to the life sciences because it unifies complex ecological principles and explains variation observed between and within species. Students at the secondary level often lack deep conceptual understanding of evolutionary theory, which is crucial to grasp topics related to primary drivers within populations such as inter- and intra-specific competition, predation, and reproductive success. Nonetheless, evolution remains a contentious topic in the United States. The prevalence of pseudoscientific belief among the U.S. populace warrants a calculated approach to deconstructing student misconceptions. This article puts forth an action-research-supported instructional strategy through which educators can identify and address core student misconceptions regarding evolutionary theory and other complex scientific phenomena, utilizing real-world and student-generated models to drive instruction.
Attitudinal Legacies of Dictatorship
Authors: Ishiyama John , Kim Taekbin
Published: February 2024

What are the longer-term consequences of premigratory experiences on the political attitudes of those who migrate out of extremely authoritarian regimes? In this paper, using data from an original survey of North Korean defectors in South Korea conducted in 2022, we examine whether attitudes on executive power, self-sacrifice for the sake of the national community (postmigration), state ownership, and the duty to participate politically, vary among North Korean defectors, and whether those attitudes are based on their individual experiences in North Korea. Although we find little evidence that defectors express a greater willingness to sacrifice for the nation, former members (especially male members) of the Workers’ Party of Korea are significantly more likely than nonparty members to express support for a strong unchecked leader. Some other indicators of elite status (such as higher education and organizational leadership) also suggest that defectors who were elites are more likely than defectors with less elite backgrounds to retain elements of the authoritarian socialization they experienced in North Korea.
Augmented renal clearance in the intensive care units: concepts to considerate in drug dosing
Authors: Charco-Roca Luisa M.
Published: February 2024

Augmented renal clearance (ARC) is a manifestation of renal function that can be seen in patients admitted to the Intensive Care Unit. Its exact prevalence is unknown and it is detected by way of an urinary measurement of creatine. ARC is defined as a creatinine clearance greater than 130 ml / min / 1.72 m2. Pathological mechanisms are not clearly defined and are probably multifactorial. For patients with confirmed ARC, dosing modifications of all renally purified medicinal products should be taken into account. The use of conventional doses can lead to the failure of the therapy with worse results for the patient and a higher economic cost for the healthcare system. Future research will determine dosages in ARC cases and the use of drug plasma concentration measurements will help us to individualize treatments.
ASSESSMENT OF CIRCULATING miRNA LEVELS IN BREAST CANCER PATIENTS DEPENDING ON CLINICAL CHARACTERISTICS AND CHEMOTHERAPY
Authors: Harashchenko О.
Published: February 2024

Background. Breast cancer (BC) stands out as the most prevalent cancer in women. The levels of miRNA expression before and after chemotherapy are considered a potential indicator for the prognosis of the disease. Aim. To study blood plasma miRNA levels in BC patients and to assess their correlation with the menopausal status, disease stage, and molecular BC subtype. Materials and Methods. Blood plasma levels of 6 miRNAs (miRNA-25, miRNA-27, miRNA-155, miRNA-200, miRNA-335, and miRNA-497) were studied in 70 BC patients and 18 healthy individuals using RT-PCR. Results. miRNA-25, miRNA-335, and miRNA-497 levels were significantly higher in BC patients, while a tendency toward a decrease in the miRNA-27 and miRNA-335 levels in premenopausal patients and high miRNA-27 levels in menopausal patients was established. After neoadjuvant chemotherapy, a decrease in the miRNA-25 and miRNA-335 levels was registered. Conclusions. The results indicated that miRNA-25, miRNA-27, miRNA-335, and miRNA-497 deserve attention as markers for assessing the efficacy of treatment of BC patients.
СANCER INCIDENCE IN UKRAINE: TRENDS IN 2010-2019 AND THE IMPACT OF COVID-19 PANDEMIC
Authors: Michailovich Yu.I. , Sumkina O.V. , Gorokh Ye.L.
Published: February 2024

Background. In 2020, a sharp decrease in the number of new cancer cases was registered in Ukraine in the setting of the quarantine restrictions due to the COVID-19 pandemic, which contrasted with the previous trends. Aim. To study trends of cancer incidence rates in Ukraine in the recent decade and to assess the impact of COVID-19 pandemic on cancer detection in 2020. Materials and Methods. Records on cancer cases diagnosed during 2010—2020 (n = 1,498,911) from the database of the National Cancer Registry of Ukraine were used; the data being submitted early in 2022. Trends of the age-standardized incidence rates in 2010—2019 were estimated by the Joinpoint Regression Program. Results. During 2010—2019, the incidence rates increased (p < 0.05) for colon, prostate, and pharyngeal cancers in males and for colon, thyroid, and pancreas in females with the rates of other prevalent cancers being stable or decreasing (lung and larynx in males, cervix and rectum in females, stomach in both genders); the incidence increased mainly at the expense of the population aged 60—74 years. A significant decrease in cancer incidence was in males aged 40—59 years. In 2020, the serious negative impact of COVID-19 outbreak on the timely detection of cancer occurred in all adult age groups of the Ukrainian population and involved all the most common cancers. The most pronounced diminution of the incidence rate was observed for non-melanoma skin cancers (by 35.9%— 37.9%); the decrements of the rates for other prevalent cancers varied from –23.0% (prostate gland) to –9.7% (pharynx) in males and from –21.2% (kidney) to –9.1% (pancreas) in females, the greatest ones being in the population aged 75+. Conclusions. The sharp drop of the cancer incidence rates registered in Ukraine 2020 is evidently the result of the limited access to healthcare facilities as well as the reduced oncological alertness of the population due to the predominant focus on COVID-19 during the pandemic. However, it is not a manifestation of a decrease in cancer incidence as such. In the following years, this may increase the proportion of advanced-stage diagnoses, the load on the cancer care system, and cancer mortality in the Ukrainian population. An evaluation of the short-termand long-term effects of the COVID-19 pandemic on the cancer burden in Ukraine requires further monitoring.
POWER PROCESSING AND CONTROL UNIT OF THE EECTRIC PROPULSION SYSTEM
Authors: Петренко О. , Алексєєнко О.А. , Толмачов В.М.
Published: February 2024

Abstract. The report presents the results of the development of the PPU-500, which is part of the SPS-500 electric propulsion system based on the ST-40 Hall thruster. PPU-500 contains all power supplies necessary for the operation of the propulsion system: discharge; electromagnet; cathode heater and keeper; power supplies for valves and heaters of the storage and feeding working substance, as well as a standby power supply that ensures the standby mode of PPU operation.The converter of the discharge power supply is built using a bridge topology with a phase-shifted output power control circuit. The remaining power supplies are built according to the topology of a step-down synchronous converter with current or voltage stabilization. The discharge power supply is a controlled power supply. The power supplies for the cathode heater and electromagnet current sources are. The accuracy of power supplies output parameters in not worse than 1.5%. The valves of the feeding system are controlled in order to stabilize the pressure in the receiver by periodically turning on/turning off the high- and low-pressure valves. For control the valves, signals taken from pressure sensors installed in the receiver are used. The PPU control unit ensures an accuracy of maintaining pressure in the receiver no worse than 2.5%. The control unit of the PPU is built using a microcontroller with an ARM core. It implements the functions of monitoring the condition of the program, restoring the program firmware if an integrity violation is detected, and the ability to remotely flash a new version. To communicate the SPS-500 with the on-board control system, a galvanically isolated CAN interface is used. It can be  also the RS485/RS42 interface.During operation of the propulsion system, operating parameters are measured using multi-channel ADCs and DACs. The obtained data, on the one hand, is used to assess the current state of the propulsion system and control Hall thruster operating modes. On the other hand, they are transmitted as telemetry signals reflecting the current state of the SPS-500, operating mode and emerging emergency conditions of the equipment. PPU is possible to alternately control two thrusters. Solid-state switches are used to switch the corresponding power sources.Testing of the PPU-500 as part of the SPS-500 propulsion system with the ST-40 Hall thruster and a flight prototype of the working substance feeding system confirmed the technical solutions adopted. The operating efficiency of PPU-500 for the nominal operating mode of the propulsion system is 94%.