bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical effect and prognostic factors of mechanical thrombectomy in the treatment of acute ischemic stroke
Authors: Li Liang , Cheng Peipei , Zhang Jiwei , Wang Guang , Hu Tiemin , Sun Fan
Published: April 2022

Objectives: To explore the clinical effect and prognostic factors of mechanical thrombectomy in the treatment of acute ischemic stroke.

Methods: The records of patients with acute ischemic stroke treated in our hospital from April 2020 to April 2021 were retrospectively selected. A total of 65 patients were treated with mechanical thrombectomy. After treatment, they were scored with modified Rankin Scale (MRS). The treatment effect and prognostic factors were analyzed.

Results: The occluded vessels were successfully opened in 65 patients. The recanalization rate was 96.92%. There were no serious complications of thrombectomy. The time from femoral artery puncture to vascular recanalization was (84.06±16.64) minutes and the number of thrombectomies was (2.52±0.71). There were 42 patients with good prognosis and 23 patients with poor prognosis. Analysis of the prognostic factors showed that the time from onset to admission in the good prognosis group was shorter, the NIHSS score before thrombectomy was higher, and the Alberta stroke program early CT Score (ASPECT) score was lower as compared to the patients in the poor prognosis group. The grade of vascular recanalization in the good prognosis group was better than that in the poor prognosis group, and the level of PCT was lower (P<0.05). Logistic regression analysis showed that the time from onset to admission, NIHSS and ASPECT scores before thrombectomy were the prognostic factors of mechanical thrombectomy in the treatment of acute ischemic stroke.

Conclusion: Mechanical thrombectomy is effective in the treatment of acute ischemic stroke and can effectively promote the recanalization of occluded vessels, but the NIHSS and ASPECT scores from the onset to the time of admission before thrombectomy can directly affect the prognosis of patients.

doi: https://doi.org/10.12669/pjms.38.5.5723

How to cite this:Li L, Cheng P, Zhang J, Wang G, Hu T, Sun F. Clinical effect and prognostic factors of mechanical thrombectomy in the treatment of acute ischemic stroke. Pak J Med Sci. 2022;38(5):---------. doi: https://doi.org/10.12669/pjms.38.5.5723

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
In silico Studies and Assessment of Antimicrobial Activities for Synthesised Nitrobenzimidazole Derivetives
Authors: M. Patel Dhaval , K. Patel Nirmal , Narolkar Swati , Mishra Arvnabh
Published: May 2022

Nitro substituted benzimidazole derivatives were synthesized using o-phenylenediamine and different aromatic acid. The reaction is carried out in ethanol as solvent at room temperature by using mechanical stirrer. Nitration of the synthesized benzimidazole derivative was carried out using mixed acid as a nitrating agent. The synthesized product characterized by using FT-IR, and 1H NMR. The synthesized benzimidazole derivative were studied for antimicrobial activity using gram -ve and gram +ve micro-organism. Maximum zone of inhibition is 18mm for B. cereus gram +ve microorganism and 17 mm for E. coli gram -ve microorganism in comparison with streptomycin as control drug. In silico studies were adopted for synthetic derivatives by Chem bioDraw, and online software tool and the synthesized compounds XY-1, XY-2 and XY-3 showed good binding affinity than streptomycin. The results suffice in vitro studies.
Patient perspectives on elective orthopaedic surgery during the COVID-19 pandemic: a comparison between patients from different ethnic backgrounds
Authors: Hodgson H , Golmohamad R , Gulati A , Pandit H , Palan J , Giannoudis P , Howard A
Published: April 2022

Introduction

Suspending elective surgery during the first wave of coronavirus (COVID-19) led to record-breaking numbers of patients on waiting lists. Patients in Black, Asian and minority ethnic (BAME) groups are disproportionately affected by COVID-19. This study compares the perspectives of patients from different ethnic backgrounds on the return to elective surgery.

Methods

Some 151 patients were sampled from cancelled operating lists at two hospitals. Semi-structured interviews focused on the impact of COVID-19, and views about resuming elective surgery. The Generalized Anxiety Disorder 7-iten Scale (GAD-7) measured anxiety. A visual analogue scale (VAS) measured pain. Data were analysed using exploratory thematic analysis.

Results

Fewer BAME patients were pleased about restarting surgery, compared with white patients (47.3% vs 82.6%, p<0.001), and a greater proportion wanted to postpone their operation until after the pandemic (21.8% vs 9.3%, p=0.048). White/white British patients had higher GAD-7 scores (2 (0–21) vs 0 (0–16), p=0.009). Black/Black British patients had significantly higher VAS scores compared with white/white British and Asian/Asian British patients (85 vs 75 vs 70 respectively, p<0.05).

Conclusion

The delay in surgery due to the pandemic has had a devastating impact on patients awaiting operations. The variation in pain and anxiety levels between ethnic groups must be addressed when redesigning services to avoid discrepancies in postoperative clinical outcomes. Patients in BAME groups are more likely to postpone their operation, which may lead to further health deterioration, psychosocial and socio-economic consequences, and poorer clinical outcomes following surgery. The thoughts, feelings and concerns of all must be considered when redesigning services to prevent health inequalities between patients from different backgrounds.
Serum TSH as a predictor of malignancy in indeterminate thyroid nodules
Authors: Amado A , Castro B , Torre AP , Graça S , Tavares A , Póvoa A , Soares C , Gonçalves G
Published: April 2022

Introduction

Thyroid nodules are lesions that are radiologically distinct from the thyroid parenchyma. Cervical ultrasound diagnoses 19–67% of nodules and is crucial in identifying those that lack cytological characterisation. Approximately 25% of biopsies reveal an indeterminate cytological result (Bethesda III), in which the risk of malignancy is variable (5–15%). The clinical importance of the diagnostic strategy used for thyroid nodules results from the need to exclude malignancy. The aim of this study was to evaluate the usefulness of serum thyroid-stimulating hormone (TSH) levels as a predictor of malignancy in cytologically indeterminate thyroid nodules.

Methods

Our retrospective study included 40 patients with cytologically indeterminate thyroid nodules seen in our hospital between January 2013 and December 2017. Clinical parameters were reviewed, including age, gender, serum TSH levels, family history of thyroid carcinoma, radiation exposure and some sonographic features of the nodules. Statistical analysis was performed using SPSS. Statistical significance was defined as p<0.05.

Results

Female gender was predominant (85%) and the mean (SD) age was 53.3 (15) years. Thyroid carcinoma was confirmed in 28% of patients. Median TSH levels were higher in patients with malignant (2.73µIU/ml) compared with benign (1.56µIU/ml) nodules (p<0.05). We demonstrated an increased risk of malignancy in patients with TSH levels of 2.68µIU/ml or above (p<0.05).

Conclusion

Higher serum TSH levels are associated with an increased risk of thyroid carcinoma in cytologically indeterminate nodules. TSH can become a fundamental diagnostic tool in stratifying the risk of malignancy and assist in diagnostic and therapeutic approaches to these nodules.
Endobronchial valve use in COVID-19 related pneumothorax and persistent air leak
Authors: Nugent TS , Aladaileh M , Donlon NE , Murphy N , Eaton D
Published: April 2022

Pneumothoraces may occur rarely in coronavirus (COVID-19) patients, often resulting from a combination of fibrotic parenchymal changes and prolonged high-pressure ventilation. Very few studies have been published describing the management of pneumothorax in the novel COVID-19 pneumonia patients. Although chest drain insertion represents the first line of treatment, a persistent pneumothorax and air leak requiring intervention could be managed by a thoracoscopic procedure or, as is the case here, by endobronchial valve insertion. Endobronchial valve insertion is a minimally invasive technique that provides a treatment option in patients with severe parenchymal COVID-19 related lung disease. As far as the authors are aware this is the first report of the use of endobronchial valves in a COVID-19 patient.
‘Never mind, we can’t help you’: young people’s experiences of the imprisonment of a sibling
Authors: Deacon Kirsty
Published: April 2022

While there has been an increasing focus on familial imprisonment within academic literature, policy and practice, where this is in respect of children and young people this has tended to focus on their parents. This narrow view of family has seen the omission of sibling imprisonment experiences from these narratives. This article explores these experiences through in-depth interviews with seven young people, aged 17–22 at the time of their interviews, but also reflecting back on when they were children and younger teenagers. By exploring aspects of loss, the barriers to being able to maintain sibling relationships in a prison, and the potentially lasting impacts on these relationships, it argues the need to recognise family more widely than we currently do. This is both in terms of not focusing solely on parental imprisonment, but also the recognition of family through their ‘practices’ and ‘display’: what they do rather than what they are.
Shifting roles, changing relations: considerations when doing ethnographic research with multiple families
Authors: Üzümcü Hamide Elif
Published: April 2022

When conducting ethnographic research, a family researcher becomes involved in the personal lives of the participants. This raises a number of concerns for the researcher when establishing relationships with family members. Drawing on qualitative data from research on children’s intra-familial privacy in Turkey, this article aims to increase awareness of several cultural aspects that may have an impact on how researchers build rapport with family members in Turkey. It reflects on a set of key considerations when doing ethnographic research with multiple families. These include the cultural struggles for children when addressing the researcher (in kinship terms such as ‘elder sister’), negotiation of the researcher’s role through participant observational activities, the changing display of family over time, the researcher’s over-involvement in family issues, and adapting to family cultures when working with families from different sociocultural and socioeconomic backgrounds.
Complex-Light Lasers
Authors: Davidson Nir , Mahler Simon , Friesem Asher , Forbes Andrew
Published: May 2022

Tailoring modal competition inside lasers is enabling novel
sources of complex light—and new approaches to light-based
computation.
Dengue virus transovarial transmission detection in Aedes aegypti from dengue hemorrhagic fever patients' residences in Denpasar, Bali
Authors: Sudarmaja I. Made , Swastika I. Kadek , Diarthini Luh Putu Eka , Prasetya I. Putu Dema , Wirawan I. Md. Ady
Published: April 2022

Background and Aim: To effectively control dengue hemorrhagic fever (DHF), it is necessary to assess the risk of vertical virus transmission in Aedes aegypti mosquitoes. This study aimed to detect dengue virus (DENV) transovarial transmission in A. aegypti collected from DHF patients' residences in Denpasar, Bali.

Materials and Methods: A. aegypti samples were acquired by rearing A. aegypti eggs collected from ovitraps placed in the homes of DHF patients. Ovitraps were installed for 7 days and viewed using a loupe to determine whether there were Aedes spp. eggs present. An immunocytochemical method was utilized with 200 samples, and virus detection was performed using a reverse transcriptase-polymerase chain reaction (RT-PCR).

Results: Of the 10 DHF patient houses fitted with ovitraps, four produced positive ovitraps from which larvae developed (house index=40%). Of the 50 ovitraps mounted in the 10 homes, 14 ovitraps were positive and contained A. aegypti eggs (ovitrap index=28%). Of these 14 positive ovitraps containing A. aegypti eggs, 10 ovitraps produced larvae. Immunocytochemical tests were conducted on A. aegypti eggs from the four houses under study. It was found that from the 200 samples collected, 197 samples could be observed, and 11 samples (5.6%) were positive for DENV antigen. RT-PCR examination conducted on mosquitoes reared from the four houses studied obtained a negative virus content result.

Conclusion: This study found the presence of DENV antigen to be as high as 5.6%. This means that potential for transovarial transmission exists within DHF patients' homes in Denpasar, Bali. Aedes control strategy in Denpasar should address this finding, in addition to the current approaches which have focused primarily on the elimination of larval breeding habitats and control of adults using insecticidal fogging during outbreaks.
EXAMINED AND ANALYSIS OF EMPIRICAL SEISMIC DAMAGE OF WORKSHOP BUILDING
Authors: Li Siqi , Chen Yong-Sheng , Liu Hong-Bo
Published: May 2022

To deeply explore the typical damage characteristics and vulnerability characteristics of workshop building (WB) in actual earthquakes, the empirical field reconnaissance and observation of the WB damaged to varying degrees in the Mw 8.0 earthquake in Wenchuan County, Sichuan Province, China on May 12, 2008 were conducted. The investigation results indicated that the typical seismic damage forms of industrial buildings in multiple intensity regions were: local and overall collapse, column cracking and crane beam displacement, collapse and cracking of wall, and damage of supporting and connecting members, the field investigation pictures of typical seismic damage were provided, respectively. According to different typical failure characteristics, the seismic damage mechanism and seismic capacity were analyzed, and the measures and suggestions to improve the seismic capacity of industrial buildings with different material categories were conducted. The conclusions can provide necessary reference for the revision of the seismic code of industrial plants and the seismic intensity scale of China.
Optimization of an integrated approach to voice correction for endocrinopathies (analytical review)
Authors: Starostina S. V. , Statsenko Ya. A. , Svistushkin V. M.
Published: April 2022

Dysphonia is a symptom of many endocrine pathologies. Hoarseness, voice fatigue, decrease of the voice pitch, reduce of the range are typical complaints for hypothyroidism, caused by an increased amount of polysaccharides and accumulation of fluid in the lamina propria of the vocal folds. An excess of growth hormone causes an overproduction of insulin-like growth factor-1, which leads to abnormalities in the craniofacial region and proliferation of the upper respiratory tract tissues, including thickening of the laryngeal cartilages, vocal folds and decreasing of the voice pitch. Hyperglycemia, changes in the balance of fluid and electrolytes in diabetes mellitus can indirectly affect the voice: xerostomia complicates phonation due to impaired hydration of the laryngeal mucosa, diabetic neuropathy often disrupts the work of the laryngeal muscles involved in voice formation. Voice changes are observed not only in endocrine disorders, but also during puberty, the phases of the menstrual cycle and during menopause. Laryngeal structures are modified under the influence of hormones and external factors, which generally changes pitch and intensity of the voice, timbre and resonance, articulation and prosodic characteristics. The purpose of this review is to summarize and systematize data on physiological and pathological voice changes in patients of different age groups and sex. The possibilities of a multidisciplinary approach to rational voice correction are demonstrated.
Early manifestation and progressive multicomponent current of McCune–Albright-Braitsev syndrome in a girl 9 years old: a clinical case and literature review
Authors: Girsh Ya. V. , Kareva M. A. , Makazan N. V. , Davygora E. N.
Published: April 2022

McCune–Albright–Braitsev Syndrome (MAB syndrome) is a very rare multisystem disease manifested by fibrous bone dysplasia, coffee-and-milk colored spots, hyperfunction of various endocrine glands and a number of pathologies of other body systems. We present a description of a clinical case of a severe progressive course of MAB Syndrome in a nine-year-old girl. With this diagnosis, the girl is observation of the girl began when she was 2.5 years old, when spots of coffee-and-milk, polyosseous fibrous dysplasia, peripheral premature sexual development against a backdrop of estrogen-­secreting ovarian cysts, multinodular goiter were detected. In the process of dynamic observation, it was noted that the child’s active growth stopped against a backdrop of deformities of the skeletal system with multiple repeated fractures of the extremities; progression of skull deformity with stenosis of the optic nerve canals and deterioration of visual acuity; development of STH hypersecretion, hypophosphatemic rickets, tachycardia. Appropriate suppressive / replacement therapy was prescribed for each of the endocrine dysfunctions. The article presents algorithms for examining a girl in dynamics, criteria for choosing a component-wise management tactics and a discussion of the features of the course of all manifestations of the Syndrome.
Clinical guidelines «Polycystic Ovary Syndrome»
Authors: Adamyan L. V. , Andreeva E. N. , Absatarova Yu. S. , Grigoryan O. R. , Dedov I. I. , Melnichenko G. A. , Suturina L. V. , Filippov O. S. , Sheremetyeva E. V. , Chernukha G. E. , Yarmolinskaya M. I.
Published: April 2022

Polycystic ovary syndrome (PCOS) is a polygenic endocrine disorder caused by both genetic and epigenetic factors. Depending on the period of a woman’s life, the clinical picture, diagnosis, and treatment tactics of the disease are different. PCOS has a complex of reproductive, metabolic and psychological characteristics. The target audience of these clinical recommendations are obstetrician-gynecologists, endocrinologists, general practitioners, general practitioners. In these clinical guidelines, all information is ranked according to the level of persuasiveness of recommendations and the reliability of evidence, depending on the number and quality of studies on this issue.
Literary Review of Translanguaging, Translating, and Interpretation in Education
Authors: Gentry Corinne
Published: April 2022

This literature review covers literature on translanguaging, translating, and interpreting in education, primarily K-12 institutions. The first article defines translanguaging and its strengths in different contexts, including its use in the English as a New Language classroom. Translanguaging offers opportunities for scaffolding and building confidence in English, while encouraging students to participate in class and feel more comfortable around peers and staff. The second article discusses multilingualism and choosing language based on social context. The third article discusses Spanish and English literacy and its impact on native Spanish speaking children. Native Spanish speaking children very rarely have opportunities to learn how to write in Spanish, and the study allows the students to have this opportunity. The fourth article discusses English-only policies in schools and cautions against them due to the environment that is created by monolingualism. The fifth article stresses the importance of interpreters in school, and the final article stresses the importance of translated written communication.
Evaluation Correlations between Emotional Intelligence Subscales and Adherence to Health Protocols during the COVID-19 Pandemic
Authors: Aliyari Farshad , Bakhtiari Maryam , Kianimoghadam Amir Sam
Published: April 2022

Introduction: To mitigate the spread of COVID-19 infection, health protocols have been recommended but some people ignore them. Emotional intelligence is a set of skills that help people to cope with the demands of the environment. The Purpose of this study was to examine the relationship between emotional intelligence subscales and adhere to health protocols during Covid-19 pandemic. Method: This cross-sectional study was advertised on social media. 341 participants completed the self-reported questionnaires through the online link. Analysis was performed to assess the kind of association by SPSS. Results: Results indicated that females, older individuals, and somewhat those with higher education levels had more adherences to the healthcare protocols. Also, some EQ subscales (e.g., Social Responsibility, Reality Testing, Flexibility, and Emotional Self-Awareness) were significantly correlated with attitude toward healthcare protocols. Conclusion: These results emphasize the possible important of emotional intelligence subscales on adherence to health protocols.
The Qibla Directional Accuracy Determination Analysis Using Spherical Trigonometric Method and Google Earth
Authors: Muhalling Rusdin , ST. Najmah , Huzaimah Nur Azizah , Idriz Mesut
Published: April 2022

This research aims to find out the methods used to determine the direction of the qibla of mosques in Kendari City and provide solutions for mosques that are not following the direction of the qibla in Kendari City. The research method used is qualitative descriptive with an empirical normative approach. The data collection methods that researchers use are interviews, observations, documentation and data analysis, namely data reduction, presentation of data, and concluding. The results showed that, first, the majority of the direction of the mosque's qibla that was the object of the study was inaccurate. This is based on the results of calculations and direct checks using the Spherical Trigonometric Calculation Formula and Google Earth that researchers have done, where the direction of the qibla of each mosque is 21°-22° from West to North and 68°, 38° from North to West. Of the 20 mosques studied, 13 mosques were inaccurate or not precisely in the qibla direction. Of the 13 mosques, 12 mosques whose deviation or deviation angle is more minor to the North, one mosque is the corner of deviation or deviation is more to the North or less to the South. Second, for mosques that are not right in the direction of the qibla, it must be directed towards the actual qibla; by the way, the mosque building must be rehab or renovation, but this is difficult because it requires a substantial cost (large) then the most accessible step at a meager cost; namely, the mosque shaf must be directed towards the qibla which is the most accessible and straightforward solution.
The Fabrication and Characterization Behavior of Cordierite Ceramic Materials with different Molar Fraction
Authors: Basheet Mohammad Hasan , Farhan Fadhil Kareem , Abed Abdulrahman N. , Alobaidi Omar , Alhayali Ali Rasim Ibrahim
Published: May 2022

The investigation was concentrated on preparation of bioactive pure cordierite ceramic and evaluate the phase transformation which excepted to form during sintering process. Cordierite prepare by chemical co precipitation, integrated Cordierite gel with water-based sol–gel which begin essentially from Alumina Al2O3, magnesium oxide MgO and silicon oxide SiO2. Different specimens were fabricated with various weight percentage of Al2O3, Mgo and SiO2 powders. All specimens were prepared in cylindrical shape by using hydraulic press at pressure of 4 bar with holding time at this pressure for 30 minutes. Firing presses achieve at 10000C and 12500C with 2 hour holding time. The characterization of microstructure has been done by using Field Emission Scanning Electron Microscope (FESEM), which revealed homogenous distribution of the compounds with few porosities. The x-ray diffraction for phase transformation which occur during sintering process. The structure analysis of specimens shows at 1250°C cordierite phase form, also the results are shown formation of cristobalite, spinel, protoestatite and corundum with cordierite phase.
Energy Management Strategy Based on Marine Predators Algorithm for Grid-Connected Microgrid
Authors: Kheiter Amel , Souag Slimane , Chaouch Abdellah , Boukortt Abdelkader , Bekkouche Benaissa , Guezgouz Mohammed
Published: April 2022

This work aims to optimize the economic dispatch problem of a microgrid system in order to cover the load of a commercial building in Algeria. The analyzed microgrid system is connected to the power grid and composed of photovoltaic panels (PV), wind turbine, battery energy storage system (BESS) and diesel generator. To ensure energy balance and the flow of energy, we have implemented an energy management strategy based on Marine Predator Algorithm (MPA) and Multilayer Perceptron Neural Network (MLPNN), which guarantee an optimal economic operation of the system. First, using historical meteorological data, the power generation is forecasted a day-ahead using MLPNN, which allows the optimization of the microgrid operation. Second, the proposed strategy has been studied under three different microgrid configurations. Eventually, the performances of MPA are compared against well-known algorithms. The results indicate that the integration of the PV-BESS microgrid system significantly reduces the daily operating cost up to 34.5%. Due to the availability of wind resources in the studied area, the addition of a wind turbine to the microgrid minimizes the operating cost by 43.96% compared to the operating cost of the power grid. In the case of selling excess energy to the main power grid, the operating cost could be decreased as much as 49.33%.
Readiness of Water Sanitation and Hygiene Facilities (WASH) as an Effort to Prevent COVID-19 Transmission in Elementary Schools at Ngaliyan District, Semarang City
Authors: Yudhana Ega Friesa , Siwiendrayanti Arum
Published: April 2022

Introduction: Ngaliyan sub-district on Semarang city has the highest cases of Covid-19 (212 cases) in July 2021. High proportion of them occurred on elementary school-aged children aged 7-12 years. Among other levels of education, this group also has the lowest levels of sanitation. This study aimed to determine the readiness of WASH facilities as an effort to prevent the transmission of COVID-19 in elementary schools at Ngaliyan Sub-District, Semarang City.Methods : This study was a descriptive observational study. Data collection techniques were carried out by observation, on 36 elementary schools in Ngaliyan District (total sampling method). Readiness of Water Sanitation and Hygiene Facilities (WASH) in each school were observed using checklist. Data were classified and compared to the requirements.Results: The results of this study indicate that 100% of primary schools in Ngaliyan sub-district have the readiness of WASH facilities. Of the 36 primary schools, 97% of schools met the requirements for clean water, 64% for the toilet conditions, 14% for the waste disposal and 100% of the waste water disposal system and 67% for the hand washing facilities.Conclusion: In general, WASH facilities in the elementary schools in Ngaliyan Sub district was ready for the transmission of COVID-19 prevention, but some improvements should be done, especially for the waste disposal, toilet conditions and hand washing facilities.
Determination of Fit to Work Status for Thyroid Cancer Survivor: A Case Study in Occupational Health Setting
Authors: Hardy Syaifoel , Tukayo Isak Jurun Hans , Fahruddin Akhir , Afzal Ridha
Published: April 2022

Introduction: A thyroid cancer worker after undergoing ablation procedure requires specific recommendation when return to work. This study aims to determine a framework of the fitness to work (FTW) status from the occupational health nursing viewpoint. The implication is to help answer the question whether the worker is fit to work as a cancer survivor.Methods: This study used a Case Study method with descriptive design. The sample was a therapist associate whose scope of work was office-based. The method applied the Test Blueprint of case management assessment by the American Board of Occupational Health Nursing (ABOHN) standard combined with the Glasgow Coma Scale (GCS) after the ablation procedure as the instrument. We analyzed the case with The Fit to Work (FTW) Model of Hybrid Model.Results: FTW  assessment showed vital signs within normal limits. Immunological examination found abnormalities. The left and right thyroid lobes were not visualized and there was no mass in the surgical bed. The client was advised for specialist follow up after 6 months. After the ablation procedure, the employee had a verbal communication disorder. The Glasgow Coma Scale (GCS) recorded point 5 hoarseness with decreased tone quantity was about 90%. Based on the medical report and his specialist’s advice, 6 months after ablation the employee’s medical condition showed improvement.Conclusion: With the At-Will Model of Hybrid as the framework to determine the fitness status, we recommended to declare him fit with restrictions and advised for regular fitness status update.
Youth Empowerment in the Integration Program of Stunting Prevalence Reduction in East Java during Covid-19 Pandemic: A Document Review
Authors: Anjaswarni Tri , Winarni Sri , Hardy Syaifoel , Kuswulandari Shanti
Published: April 2022

Introduction: More than 25% of East Java regencies and cities had stunting prevalence rates higher than the national figure. The involvement of the youths to reduce stunting is important in helping to overcome this national health problem. This study aimed to identify areas in East Java that have stunting prevalence rates above the national rate and assisted in the preparation of a program called the Youth Empowerment for Stunting Reduction Program (YESREP).Methods: This descriptive study used document review by PRISMA stages. At the initial stage, 453 documents were filtered from Google Scholar (n=29), Pubmed (n=12), SagePub (n=20), Semantic Scholar (n=6), others (n =136), while the remaining (n=260) were discarded. The search keywords were ’youth empowerment’, ‘stunting’, and ‘Covid-19’. The inclusion criteria were stunting cases, youth empowerment, and the Covid-19 pandemic. The documents screened were journals with quantitative, qualitative, document review methods, year of publication:2017-2022, focusing on youth empowerment and stunting, and in English or Indonesian languages. The tool used for the final document selection used PICOT model.Results: Youth empowerment was one of the effective methods in reducing the stunting prevalence. However, training programs, orientation, continuity, guidance, and follow-up are needed. The challenges were in funds, time, and readiness of the human resources involved in the implementation of YESREP.Conclusion: YESREP as a concept, was effective in reducing stunting prevalence, but still have some limitations. This study recommends conducting experimental research through a pilot project,
Application of exogenous auxin and gibberellin regulates the bolting of lettuce (Lactuca sativa L.)
Authors: Wang Yubo , Li Bingyan , Li Yunfeng , Du Wei , Zhang Yueting , Han Yingyan , Liu Chaojie , Fan Shuangxi , Hao Jinghong
Published: April 2022

Plant bolting is regulated and controlled by various internal and external factors. We aimed to provide an improved method for breeding to determine whether there is a synergism between hormones and to explore the regulatory effect of plant hormones on the bolting of leaf lettuce. Lettuce plants were sprayed with exogenous auxin and gibberellin separately or in combination. The specific bolting period was determined by the change in stem length and cytological observation. The dynamic changes in endogenous hormones and genes closely related to bolting were analyzed. Treatment with gibberellin alone and the combined application of auxin and gibberellin induced bolting on the fourth day, and treatment with auxin alone resulted in bolting on the eighth day. In the early bolting stage, the auxin contents in the stems of the treatment groups, especially the combined gibberellin and auxin group, were higher than those of the control group. After the application of exogenous auxin and gibberellin, we found that the expression of the ARF8 and GID1 genes was upregulated. Based on the results of our study, combined treatment with exogenous gibberellin and auxin was the best method to promote the bolting of leaf lettuce, and the ARF8 and GID1 genes are closely related to this process.
Analysis of genetic characteristics of 436 children with dysplasia and detailed analysis of rare karyotype
Authors: Miao Zong-Yu , Chen Shi-Feng , Wu Hong , Liu Xiao-Yan , Shao Hui-Yuan
Published: April 2022

Chromosomal abnormality is one of the important causes of dysplasia in children. However, due to regional and ethnic differences, the reported rates of chromosomal abnormalities in patients with dysplasia vary greatly. Moreover, the clinical manifestations in children with rare chromosomal diseases were heterogeneous. So, we retrospectively analyzed the karyotype results of 436 children with dysplasia and conducted a detailed analysis of rare chromosomal diseases. The results showed that chromosomal abnormalities were present in 181 of 436 cases. Intellectual disability, dysmorphology, congenital malformations, the disorder of sexual development, and short stature were the main five clinical symptoms in children with chromosomal abnormalities. Moreover, 136 cases of Trisomy 21 (Tri21) were detected, of which 130 were standard Tri21, 5 were robertsonian Tri21, and 1 was chimera type. In addition, 16 cases of rare abnormal karyotype, including complex Tri21, complex Turner syndrome, 4p-syndrome, 18q-syndrome, and 5p-syndrome, were also detected. In summary, chromosome abnormality is one of the important causes of dysplasia in children. Furthermore, prenatal screening and diagnosis could play a great significance in preventing dysplasia in children. In addition, the retrospective analysis of rare cases is valuable for clinical diagnosis and risk assessment of recurrence.
Reference intervals for Sysmex XN hematological parameters as assessed in the Dutch Lifelines cohort
Authors: L. van Pelt Joost , Klatte Stefanie , Hwandih Talent , Barcaru Andrei , Riphagen Ineke J. , Linssen Jo , Bakker Stephan J.L.
Published: April 2022

Objectives

Our aim was to derive reference intervals for all Sysmex XN hematology analyzer parameters. The rationale behind the study was the lack of reference intervals for the XN analyzer cell population data (CPD) and functional parameters.

Methods

Fresh fasting blood samples from 18,484 participants in the Dutch Lifelines study were analyzed using two automated XN analyzers. Structured health questionnaire data were used to select a subgroup of 15,803 apparently healthy individuals for inclusion in the reference population. The Latent Abnormal Values Exclusion (LAVE) approach was used to reduce the influence of latent diseases in the reference population on the resulting reference intervals. We applied analysis of variance to judge the need for partitioning of the reference intervals by sex or age.

Results

We report reference intervals for 105 XN analyzer hematological parameters with and without applying LAVE. Sex-related partitioning was required for red blood cells, (RBC, RBC-O), hemoglobin (HGB, HGB-O), hematocrit (HCT), mean corpuscular hemoglobin concentration (MCHC), reticulocyte production index (RPI), and side scattered light intensity of the red blood cell population in the RET channel (RBC-Z). Partitioning for age was not warranted. Body mass index (BMI) and smoking had moderate influence on a minority of the parameters.

Conclusions

We provide reference intervals for all Sysmex XN analyzer routine, CPD and functional parameters, using a direct approach in a large cohort in the Netherlands.
Research on data mining method of network security situation awareness based on cloud computing
Authors: Zhou Ying , Zhao Guodong , Alroobaea Roobaea , Baqasah Abdullah M. , Miglani Rajan
Published: April 2022

Due to the complexity and versatility of network security alarm data, a cloud-based network security data extraction method is proposed to address the inability to effectively understand the network security situation. The information properties of the situation are generated by creating a set of spatial characteristics classification of network security knowledge, which is then used to analyze and optimize the processing of hybrid network security situation information using cloud computing technology and co-filtering technology. Knowledge and information about the security situation of a hybrid network has been analyzed using cloud computing strategy. The simulation results show that a cyber security crash occurs in window 20, after which the protection index drops to window 500. The increase in the security index of 500 windows is consistent with the effectiveness of the concept of this document method, indicating that this document method can sense changes in the network security situation. Starting from the first attacked window, the defense index began to decrease. In order to simulate the added network defense, the network security events in the 295th time window were reduced in the original data, and the defense index increased significantly in the corresponding time period, which is consistent with the method perception results, which further verifies the effectiveness and reliability of this method on the network security event perception. This method provides high-precision knowledge of network security situations and improves the security and stability of cloud-based networks.
Mediale Inszenierung geteilter Autor*innenschaften: Pauline Viardot-Garcìas Rollenporträts als Orphée (Paris, Disdéri, 1859)
Authors: Fischer Christine
Published: April 2022

The methodology and subject matter of this essay venture into the disciplinary borderlands of musicology. Taking Disdéri’s carte-de-visite portraits of the singer Pauline Viardot-Garcìa as a starting point, it attempts to broaden the notion of of the author for a historical period that quintessentially stood for the establishment of the concept of genius and thus for a definition and limitation of authorship as individual and singular. The article combines an interdisciplinary approach by considering image and media theory, theories of art and its practices, alongside historical musicological methods. Its theoretical perspective is situated at the intersection of performativity and media theory via the concepts of the ›messenger figure‹ (Botenfigur) and the ›reading of traces‹ (Spurenlesen) both according to Krämer, thus opening up a historical resonance space for contemporary music practices. As a consequence, the re-perspectivization goes beyond the basic understanding that multiple authorships are at work in every form of sounding music. Instead, it fixes diverse facets of the term authorship on a concrete example and reframes them methodologically. Thus, as a basis for a systematic generalization in music research, a model is proposed that makes medial transitions in performatively negotiated authorships describable, categorizable, and at the same time historicizable. With these interdisciplinary concerns in mind, Viardot-Garcìa’s photographic portraits in her role as Orphée in Gluck’s opera of the same name from 1859 appear to have been instrumentalized in a multilayered representational way: as images standing for a performance, as a photographic image reminiscent of a painting, as a depiction of classical Greek costume that takes on meaning for the present, as the visual standing in for the acoustic, as a depiction of a female singer embodying a man, and finally also of a title role standing in for an opera as a whole. How exactly these relations of representation are to be grasped – both in the French Gluck opera revival and in the photographic images discussed – has not yet been explored in depth. To attempt to entangle all these meanings is not motivated by trying to identify the ›actual‹ portions of the musical adaptations made by different persons to Gluck’s opera in the course of its 1859 revivals. Rather, this new perspective on the carte-de-visite photographs is intended to outline Viardot-Garcìa’s figure with the help of the numerous functions the singer assumed in the production. The essay thus looks at a blind spot that is still dominant in music research, namely the question of the methodological framing of performative authorship in historical perspective. It questions the critical concepts of ›messenger figure‹ and of the ›reading of traces‹ not only for their suitability to grasp the basic questions of the example dealt with in the text, but also for their potential for generalization.
Konzepte singulärer und pluraler Autorschaft in Filmkritik und Filmproduktion
Authors: Kamp Werner
Published: April 2022

Debates about authorship in cinema have held a privileged position in film studies since the 1950s, when the young generation of critics of the film journal Cahiers du Cinema formulated the politique des auteurs. This critical strategy proposed that the director of a film was the major creative source of the finished work. Since this assumption contradicts the industrial and collaborative character of the film medium, the politique has been questioned, attacked and reformulated ever since its beginnings. The auteur theory was appropriated and deconstructed under the influence of structuralist and poststructuralist theories that questioned the very concepts of individual creativity and self-expression. Nevertheless, questions about authorship in cinema did not vanish but were developed in many ways. If film is regarded not only as an art form but as a commodity, the director’s name cannot only be regarded as a sign of a discernible style (a ›world view‹), but as a brand name. ›Scorsese‹, ›Tarantino‹, ›Lynch‹, ›Nolan‹ – these names imply certain images, dramatic approaches, and themes. They also serve as a label for marketing a product. Directors and producers like Steven Spielberg or Ridley Scott lend their names to a certain kind of media production (film or television series) that raises expectations associated with their work. They do not necessarily work as a director. As producers – or even only as the owners of a production company – they may function as a kind of team leader, leaving the creative work to hired teams. In television, the showrunner is the major creative and managing force in the production of a series that is scripted, shot, and directed by several production crews simultaneously. Film and media studies have sought to discern the structures of collective working from historical and contemporary perspectives. Bordwell and others have described the (Hollywood) system and its mode of production, that defined the auteurs’ work. When looking closer at ›the system‹, it becomes obvious that there are different kinds of authorship in existence. Recent production studies on the working conditions in todays’ television have sought to analyse the structures of working together and ask questions about individual agency. The growing awareness of collective authorship promotes new ways of close film analysis. The German television series Babylon
Berlin here serves as an example of a major contemporary media production with multiple creative influences and explicit collective authorship. A closer look at the successful series reveals the impact of this plurality on its storytelling and form.
An investigation and analysis of plasmonic modulators: a review
Authors: Chauhan Diksha , Sbeah Zen , Dwivedi Ram Prakash , Nunzi Jean-Michel , Thakur Mohindra Singh
Published: April 2022

Plasmonics is an emerging and very advantageous technology which provides high speed and tiny size devices for fulfilling the demand of today’s high-speed world. SPPs are the information carrying elements in plasmonics, which are capable of breaking the diffraction limit. Plasmonics technology has shown its application in uncountable nanophotonic applications like switching, filtering, light modulation, sensing and in many more fields. Modulators are the key components of integrated photonic system. Various modulators which work on different effects are discussed in this study for providing a universal idea of modulators to researchers. Some useful plasmonic active materials are also discussed which are used in most of plasmonic modulators and other active devices. Previously, many researchers have worked on many kinds of modulators and switches, which operate on different kind of operating principles. For providing an overview about plasmonic modulators, their classification and their operation, we have discussed the state of art of some previously introduced modulators and switches which operates on electro-refractive effects and include electro-optic effect, Pockels effect, free charge carrier dispersion effect, phase change effect, elasto-optic effect, magneto-optic effect, and thermo-optic effect. Instead of different effects used in plasmonic switches and modulators different active materials like liquid crystals, graphene, vanadium di-oxide, chalcogenides, polymers, indium tin oxide, bismuth ferrite, barium titanate, and lithium niobate are also explained with their properties. Additionally, we also compared modulators based on different effects in terms of their design characteristics and performances.
High calcium content of Eucalyptus dunnii wood affects delignification and polysaccharide degradation in kraft pulping
Authors: Vegunta Vijaya , Senthilkumar Eashwara Raju , Lindén Pär , Sevastyanova Olena , Vilaplana Francisco , Garcia Andres , Björk Maria , Jansson Ulla , Henriksson Gunnar , Lindström Mikael E.
Published: May 2022

Eucalyptus dunnii is cultivated in Uruguay for kraft pulping purposes. However, depending on the growth site, the kraft pulping properties of the wood vary highly, and in some cases, pulping is difficult. Different batches of wood were chemically characterized and the only significant difference related to the pulping properties was the calcium content. The calcium appears to at least partly be present in the form of crystals in the lumen. Kraft pulping experiments on wood with different calcium contents indicated that high calcium led to slower delignification, and higher yield losses. Hexeneuronic acid formation was not significantly affected. Possible mechanistic explanations for these effects are discussed.
Closed-loop recycling and fabrication of hydrophilic CNT films with high performance
Authors: Zhao Jiang , Wang Shuangyuan , Wang Qiufan , Zhang Daohong
Published: April 2022

Carbon nanotube (CNT) film has attracted tremendous attention in functional material research for its unique structure and excellent properties. However, pristine CNT (PCNT) film is hydrophobic, and mechanical strength and conductivity are poor than reported individual CNT. These challenges impede its wide application. Highly efficient closed-loop recycling of both monomer and CNT film is a major challenge. Herein, hydrophilic CNT film with high mechanical strength and conductivity was prepared under the synergistic effects of in situ nitrogen doping and thiol-ene click reaction. The tensile strength, Young’s modulus, and electrical conductivity both in perpendicular and in longitudinal directions are 1,362, 1,658, 222, and 218% higher than those of PCNT film. Closed-loop recycling of CNT film and monomer with high recyclability (100 and 86.72%) has been achieved in a gentle acid environment. The CNT films are 100% recovered and reused to fabricate thiol-functionalized CNT film without deterioration of performance after three cycles, which provides a novel strategy for the preparation of high-performance CNT film and a pathway for high-efficiency closed-loop recycling of CNT film and monomer.