bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 3 from Role of WNT7B-induced Noncanonical Pathway in Advanced Prostate Cancer
Authors: Zheng Dali , Decker Keith F. , Zhou Tianhua , Chen Jianquan , Qi Zongtai , Jacobs Kathryn , Weilbaecher Katherine N. , Corey Eva , Long Fanxin , Jia Li
Published: April 2023

PDF file - 45K, Levels of WNT7B in LuCaP PC xenografts
Supplementary Table 2 from Role of WNT7B-induced Noncanonical Pathway in Advanced Prostate Cancer
Authors: Zheng Dali , Decker Keith F. , Zhou Tianhua , Chen Jianquan , Qi Zongtai , Jacobs Kathryn , Weilbaecher Katherine N. , Corey Eva , Long Fanxin , Jia Li
Published: April 2023

PDF file - 53K, RNA-seq results for all WNT genes
Supplementary Figure 3 from EpCAM Modulates NF-κB Signaling and Interleukin-8 Expression in Breast Cancer
Authors: Sankpal Narendra V. , Fleming Timothy P. , Gillanders William E.
Published: April 2023

PDF file - 23K, EpCAM knockdown in MCF-7 decreased IL-8 expression after IL1b stimulation.
Table S2 from Clinically Relevant microRNAs in Ovarian Cancer
Authors: Zhang Shu , Lu Zhen , Unruh Anna K. , Ivan Cristina , Baggerly Keith A. , Calin George A. , Li Zongfang , Bast Robert C. , Le Xiao-Feng
Published: April 2023

Table S2. miRNAs correlate with differentially expressed genes.
Supplementary Figure 4 from Migfilin Regulates Esophageal Cancer Cell Motility through Promoting GSK-3β–Mediated Degradation of β-Catenin
Authors: He Huan , Ding Fang , Li Yi , Luo Aiping , Chen Hongyan , Wu Chuanyue , Liu Zhihua
Published: April 2023

PDF file - 221K
Supplementary Figure 2 from Migfilin Regulates Esophageal Cancer Cell Motility through Promoting GSK-3β–Mediated Degradation of β-Catenin
Authors: He Huan , Ding Fang , Li Yi , Luo Aiping , Chen Hongyan , Wu Chuanyue , Liu Zhihua
Published: April 2023

PDF file - 116K
Figure S3 from Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase
Authors: Peng Hongzhuang , Cassel Joel , McCracken Daniel S. , Prokop Jeremy W. , Sementino Eleonora , Cheung Mitchell , Collop Paul R. , Polo Alexander , Joshi Surbhi , Mandell Jacob P. , Ayyanathan Kasirajan , Hinds David , Malkowicz S. Bruce , Harbour J. William , Bowcock Anne M. , Salvino Joseph , Kennedy Eileen J. , Testa Joseph R. , Rauscher Frank J.
Published: April 2023

S3. Domain architecture of human BAP1 and ASXL2 and the proteins/domains used in this study
Figure S2 from Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase
Authors: Peng Hongzhuang , Cassel Joel , McCracken Daniel S. , Prokop Jeremy W. , Sementino Eleonora , Cheung Mitchell , Collop Paul R. , Polo Alexander , Joshi Surbhi , Mandell Jacob P. , Ayyanathan Kasirajan , Hinds David , Malkowicz S. Bruce , Harbour J. William , Bowcock Anne M. , Salvino Joseph , Kennedy Eileen J. , Testa Joseph R. , Rauscher Frank J.
Published: April 2023

S2. ASXL structure and evolution
Supplementary Data 3 from Suberoylanilide Hydroxamic Acid as a Radiosensitizer through Modulation of RAD51 Protein and Inhibition of Homology-Directed Repair in Multiple Myeloma
Authors: Chen Xufeng , Wong Patty , Radany Eric H. , Stark Jeremy M. , Laulier Corentin , Wong Jeffrey Y.C.
Published: April 2023

PDF file - 152K, (A) Western blotting assay; (B) Densitometry for changes of gamma-H2AX. MM cells were treated with or without 200 nM of SAHA for 16 hours, followed by 6 Gy IR. Whole cell extracts were prepared at indicated time points after IR, and analyzed by western blot assay with anti-gamma-H2AX antibody. Anti-tubulin antibody was included as a loading control
Supplementary Table 1, Figure 1 Legend from SPINDLIN1 Promotes Cancer Cell Proliferation through Activation of WNT/TCF-4 Signaling
Authors: Wang Jing-Xue , Zeng Quan , Chen Lin , Du Ji-Chao , Yan Xin-Long , Yuan Hong-Feng , Zhai Chao , Zhou Jun-Nian , Jia Ya-Li , Yue Wen , Pei Xue-Tao
Published: April 2023

PDF file - 127K
Supplementary Figure 1 from The E6 Oncoprotein from HPV16 Enhances the Canonical Wnt/β-Catenin Pathway in Skin Epidermis In Vivo
Authors: Bonilla-Delgado José , Bulut Gülay , Liu Xuefeng , Cortés-Malagón Enoc M. , Schlegel Richard , Flores-Maldonado Catalina , Contreras Rubén G. , Chung Sang-Hyuk , Lambert Paul F. , Üren Aykut , Gariglio Patricio
Published: April 2023

PDF file - 109K, HPV16-E6 but not HPV16-E7 oncoprotein enhances canonical Wnt/�-catenin pathway in cultured cells. (A) COS7 cells were transiently transfected with the TCF/B-catenin dependent luciferase reporter construct (TOPFLASH) and Renilla together with one or two of the following expression vectors encoding the following: HPV16-E6 (E6), HPV16-E7 (E7), Dvl2 or �-catenin (B-cat). Luciferase activity from culture cells was analyzed 48 h after transfection and is shown as normalized to total protein. HPV16-E6 but not E7 significantly induced TOPFLASH activity with or without B-cat cotransfection (A) or Dvl2 cotransfection (B) co-transfection, which suggests that E6 may positively modulate canonical Wnt signaling. The Renilla signal and empty vector were used to normalize luciferase activity.
Supplementary Figure 8 from EWS/FLI1 Regulates EYA3 in Ewing Sarcoma via Modulation of miRNA-708, Resulting in Increased Cell Survival and Chemoresistance
Authors: Robin Tyler P. , Smith Anna , McKinsey Erin , Reaves Lisa , Jedlicka Paul , Ford Heide L.
Published: April 2023

PDF file - 17K, Relapse-free survival curve comparing patients with both low miR-708 and high EYA3 versus all others
Supplementary Figure 5 from EWS/FLI1 Regulates EYA3 in Ewing Sarcoma via Modulation of miRNA-708, Resulting in Increased Cell Survival and Chemoresistance
Authors: Robin Tyler P. , Smith Anna , McKinsey Erin , Reaves Lisa , Jedlicka Paul , Ford Heide L.
Published: April 2023

PDF file - 18K, miR-145 does not correlate with EYA3 in human Ewing's sarcoma samples
Supplementary Figure 1 from Prometastatic NEDD9 Regulates Individual Cell Migration via Caveolin-1–Dependent Trafficking of Integrins
Authors: Kozyulina Polina Y. , Loskutov Yuriy V. , Kozyreva Varvara K. , Rajulapati Anuradha , Ice Ryan J. , Jones Brandon C. , Pugacheva Elena N.
Published: April 2023

Supplementary Figure 1. (A). ECIS-BT549-shCon or shNEDD9 (N1, N4) cells, 5h of adhesion/spreading ;quantification of electrical impedance normalized to control +/-S.E.M; n=4; one way ANOVA: *p< 0.0157 shCon/N1or N4; (B). Boyden chamber migration assay with MDA-MB-231 cells treated with siCon or siN2 for 8h, quantification of RFU (% to siCon assigned as 100%) +/-S.E.M in ; n=3, * p<0.001, t-test (C). Invasion assay, MDA-MB-231-shCon, -shNEDD9 (N1, N4). Quantification of RFU (% to shCon assigned as 100%) +/-S.E.M in ; n=4; one-way ANOVA: *p<0.0001 for Con/N1 or/N4; (D). FACS, integrin b4 surface staining in shCon, shNEDD9 (N1, N4) MDA-MB-231 cells; graphs are mean values of RFU, % to shCon (assigned as 100%) +/-S.E.M; one-way ANOVA; integrin b4: *p<0.02 for shCon/N1 and N4; (E). WB analysis of whole cell lysate (WCL, bottom panel)) with anti-integrin b1 antibody and immunoprecipitated (IP) with streptavidin agarose biotinylated integrin b1 from shCon-, shNEDD9 (N1, N4)-MDA-MB-231cells:Not stripped with MESNA (F). Quantification of WBs as in (E) normalized to the loading in WCL by GAPDH, n=3, graphs are mean relative intensity units (RIU), (%) of shCon (100%) +/-S.E.M; one-way ANOVA *p< 0.0001. (G) Quantification of Alexa647-anti-Integrin b1 antibody uptake by MDA-MB-231 expressing either GFP-empty or GFP-b1 integrin; normalized to maximum RFU in each dataset (100%); % RFU+S.E.M; 10 cells/treatment; F-test for fitted lines p is non-significant.
Supplementary Figure 2 from EWS/FLI1 Regulates EYA3 in Ewing Sarcoma via Modulation of miRNA-708, Resulting in Increased Cell Survival and Chemoresistance
Authors: Robin Tyler P. , Smith Anna , McKinsey Erin , Reaves Lisa , Jedlicka Paul , Ford Heide L.
Published: April 2023

PDF file - 29K, EYA3 is not a direct transcriptional target of EWS/FLI1
Supplementary Figure 1 from EWS/FLI1 Regulates EYA3 in Ewing Sarcoma via Modulation of miRNA-708, Resulting in Increased Cell Survival and Chemoresistance
Authors: Robin Tyler P. , Smith Anna , McKinsey Erin , Reaves Lisa , Jedlicka Paul , Ford Heide L.
Published: April 2023

PDF file - 28K, Expression of EYA family members across Ewing's sarcoma cell lines and human mesenchymal stem cells, as shown by qRT-PCR
Supplemental Figure Legends and Tables 1-2 from TNF-α Induces Epithelial–Mesenchymal Transition of Renal Cell Carcinoma Cells via a GSK3β-Dependent Mechanism
Authors: Ho Ming-Yi , Tang Shye-Jye , Chuang Mei-Jen , Cha Tai-Lung , Li Jing-Yao , Sun Guang-Huan , Sun Kuang-Hui
Published: April 2023

PDF file- 78K, Table S1: Pathology of clinical specimens. Table S2: Sequences of primer pairs used in RT-PCR or RT-qPCR
Supplementary Data from Cell Cycle Regulator Gene CDC5L, a Potential Target for 6p12-p21 Amplicon in Osteosarcoma
Authors: Lu Xin-Yan , Lu Yaojuan , Zhao Yi-Jue , Jaeweon Kim , Kang Jason , Xiao-Nan Li , Ge Gouqing , Meyer Rene , Perlaky Laszlo , Hicks John , Chintagumpala Murali , Cai Wei-Wen , Ladanyi Marc , Gorlick Richard , Lau Ching C. , Pati Debananda , Sheldon Michael , Rao Pulivarthi H.
Published: April 2023

Supplementary Data from Cell Cycle Regulator Gene CDC5L, a Potential Target for 6p12-p21 Amplicon in Osteosarcoma
Supplementary Figure 5 from The Heterochronic microRNA let-7 Inhibits Cell Motility by Regulating the Genes in the Actin Cytoskeleton Pathway in Breast Cancer
Authors: Hu Xiaowen , Guo Jinyi , Zheng Lan , Li Chunsheng , Zheng Tim M. , Tanyi Janos L. , Liang Shun , Benedetto Chiara , Mitidieri Marco , Katsaros Dionyssios , Zhao Xia , Zhang Youcheng , Huang Qihong , Zhang Lin
Published: April 2023

PDF file - 956K, Fig. S5. let-7b inhibits breast cancer cell motility.
Supplementary Figure 3 from The Heterochronic microRNA let-7 Inhibits Cell Motility by Regulating the Genes in the Actin Cytoskeleton Pathway in Breast Cancer
Authors: Hu Xiaowen , Guo Jinyi , Zheng Lan , Li Chunsheng , Zheng Tim M. , Tanyi Janos L. , Liang Shun , Benedetto Chiara , Mitidieri Marco , Katsaros Dionyssios , Zhao Xia , Zhang Youcheng , Huang Qihong , Zhang Lin
Published: April 2023

PDF file - 1288K, Fig. S3. Stable expression of let-7 precursor inhibits breast cancer cell migration in vitro.
Supplemental Figure 4 from Exploitation of Castration-Resistant Prostate Cancer Transcription Factor Dependencies by the Novel BET Inhibitor ABBV-075
Authors: Faivre Emily J. , Wilcox Denise , Lin Xiaoyu , Hessler Paul , Torrent Maricel , He Wei , Uziel Tamar , Albert Daniel H. , McDaniel Keith , Kati Warren , Shen Yu
Published: April 2023

Dose-dependent induction of G1 arrest and senescence by ABBV-075.
Supplemental Figure 2 from Exploitation of Castration-Resistant Prostate Cancer Transcription Factor Dependencies by the Novel BET Inhibitor ABBV-075
Authors: Faivre Emily J. , Wilcox Denise , Lin Xiaoyu , Hessler Paul , Torrent Maricel , He Wei , Uziel Tamar , Albert Daniel H. , McDaniel Keith , Kati Warren , Shen Yu
Published: April 2023

ABBV-075 inhibits ETS family member ETV1 target gene transcription.
Supplemental Figure 1 from Exploitation of Castration-Resistant Prostate Cancer Transcription Factor Dependencies by the Novel BET Inhibitor ABBV-075
Authors: Faivre Emily J. , Wilcox Denise , Lin Xiaoyu , Hessler Paul , Torrent Maricel , He Wei , Uziel Tamar , Albert Daniel H. , McDaniel Keith , Kati Warren , Shen Yu
Published: April 2023

ABBV-075 inhibits AR-dependent transcription and growth.
Supplementary Tables 1-6 from TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer
Authors: Mokkapati Sharada , Porten Sima P. , Narayan Vikram M. , Lim Amy H. , Jayaratna Isuru S. , Roth Beat , Cheng Tiewei , Navai Neema , Wszolek Matthew , Melquist Jonathan , Manyam Ganiraju , Choi Woonyoung , Broom Bradley , Pretzsch Shanna , Czerniak Bogdan , McConkey David J. , Dinney Colin P. N.
Published: April 2023

Supplemental Table 1. List of top 10 genes downregulated and 10 genes upregulated in LN metastasis samples. Supplemental Table 2. Hallmark pathways enriched in the metastasis samples. Supplemental Table 3. Hallmark pathways enriched in the primary tumor samples. Supplemental Table 4. List of genes altered by TCF21 overexpression in UC3. Supplemental Table 5. List of genes altered by TCF21 overexpression in LN cells isolated from UC13 xenografts. Supplemental Table 6. List of genes altered by TCF21 in distant metastasis cells isolated from UC13 xenografts.
Supplementary Figures 1-7 from TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer
Authors: Mokkapati Sharada , Porten Sima P. , Narayan Vikram M. , Lim Amy H. , Jayaratna Isuru S. , Roth Beat , Cheng Tiewei , Navai Neema , Wszolek Matthew , Melquist Jonathan , Manyam Ganiraju , Choi Woonyoung , Broom Bradley , Pretzsch Shanna , Czerniak Bogdan , McConkey David J. , Dinney Colin P. N.
Published: April 2023

Supplemental Figure 1. Gene set enrichment analysis. Supplemental Figure 2. TCF21 expression analysis. Supplemental Figure 3. TCF21 expression in cell lines. Supplemental Figure 4. Loss-of-function and gain-of-function studies of TCF21 Supplemental Figure 5. CD24 and CD44 expression in TCF21 OE UM-UC3 and UM-UC13 cells. Supplemental Figure 6. GSEA analysis of common pathways altered between the three cell lines. Supplemental Figure 7. Heatmap of hierarchical clustering of luminal markers showing differential expression after TCF21 upregulation in UC13 LN (A) and UC13 MET (B) cells.
Supplementary Figures 1-4 from PIK3CA and p53 Mutations Promote 4NQO-Initated Head and Neck Tumor Progression and Metastasis in Mice
Authors: García-Carracedo Darío , Cai Yi , Qiu Wanglong , Saeki Kiyoshi , Friedman Richard A. , Lee Andrew , Li Yinglu , Goldberg Elizabeth M. , Stratikopoulos Elias E. , Parsons Ramon , Lu Chao , Efstratiadis Argiris , Philipone Elizabeth M. , Yoon Angela J. , Su Gloria H.
Published: April 2023

Figure S1. Experimental scheme. Figure S2. Immunohistochemical analysis of the E20/p53 mouse. Figure S3. Representative YFP (+) metastatic cells isolated from the lymph node of an E20p53(YFP) double mutant mouse. Figure S4. Combination index calculation using COMPUSYN indicates a synergy between BYL719 and cisplatin in vitro in an E20/p53 SCC cell line, S24-658.
Supplementary Figure 1 from Basal-like Breast Cancer Cells Induce Phenotypic and Genomic Changes in Macrophages
Authors: Stewart Delisha A. , Yang Yinmeng , Makowski Liza , Troester Melissa A.
Published: April 2023

PDF file - 64K, Gene expression heatmap data of THP-1 macrophages differentiated by classical stimuli on Agilent 4x44k microarrays.
Supplementary Legends for Table 1 and Figures 1-7 from SUZ12 Promotes Human Epithelial Ovarian Cancer by Suppressing Apoptosis via Silencing HRK
Authors: Li Hua , Cai Qi , Wu Hong , Vathipadiekal Vinod , Dobbin Zachary C. , Li Tianyu , Hua Xiang , Landen Charles N. , Birrer Michael J. , Sánchez-Beato Margarita , Zhang Rugang
Published: April 2023

PDF file - 122K
Supplementary Fig. 2 from Hypoxia Attenuates Trastuzumab Uptake and Trastuzumab-Emtansine (T-DM1) Cytotoxicity through Redistribution of Phosphorylated Caveolin-1
Authors: Indira Chandran Vineesh , Månsson Ann-Sofie , Barbachowska Magdalena , Cerezo-Magaña Myriam , Nodin Björn , Joshi Bharat , Koppada Neelima , Saad Ola M. , Gluz Oleg , Isaksson Karolin , Borgquist Signe , Jirström Karin , Nabi Ivan Robert , Jernström Helena , Belting Mattias
Published: April 2023

S2. Phospho-kinase antibody array analyses of normoxia (a) or hypoxia (b) level expressed as normalized to reference standard.
Supplementary Fig. 1 from Hypoxia Attenuates Trastuzumab Uptake and Trastuzumab-Emtansine (T-DM1) Cytotoxicity through Redistribution of Phosphorylated Caveolin-1
Authors: Indira Chandran Vineesh , Månsson Ann-Sofie , Barbachowska Magdalena , Cerezo-Magaña Myriam , Nodin Björn , Joshi Bharat , Koppada Neelima , Saad Ola M. , Gluz Oleg , Isaksson Karolin , Borgquist Signe , Jirström Karin , Nabi Ivan Robert , Jernström Helena , Belting Mattias
Published: April 2023

S1. Caspase induction in SKBR3 cells pre-incubated for 20 h in normoxia or hypoxia and treated with T-DM1 was measured using the Caspase-Glo 3/7 assay kit and the results are shown as mean luminescence (measured in relative light units [RLU]).
Supplementary Figure 4 from SUZ12 Promotes Human Epithelial Ovarian Cancer by Suppressing Apoptosis via Silencing HRK
Authors: Li Hua , Cai Qi , Wu Hong , Vathipadiekal Vinod , Dobbin Zachary C. , Li Tianyu , Hua Xiang , Landen Charles N. , Birrer Michael J. , Sánchez-Beato Margarita , Zhang Rugang
Published: April 2023

PDF file - 41K, 5-Azacytidine (5-AzaC) does not upregulate HRK expression in EOC cells
Supplementary Figure 1 from SUZ12 Promotes Human Epithelial Ovarian Cancer by Suppressing Apoptosis via Silencing HRK
Authors: Li Hua , Cai Qi , Wu Hong , Vathipadiekal Vinod , Dobbin Zachary C. , Li Tianyu , Hua Xiang , Landen Charles N. , Birrer Michael J. , Sánchez-Beato Margarita , Zhang Rugang
Published: April 2023

PDF file - 2MB, SUZ12 is expressed at higher levels in human EOC cells
Supplementary Figure 2 from Environmental Estrogens Differentially Engage the Histone Methyltransferase EZH2 to Increase Risk of Uterine Tumorigenesis
Authors: Greathouse K. Leigh , Bredfeldt Tiffany , Everitt Jeffrey I. , Lin Kevin , Berry Tia , Kannan Kurunthachalam , Mittelstadt Megan L. , Ho Shuk-mei , Walker Cheryl L.
Published: April 2023

PDF file - 691K, Lysates were collected from pooled (2-3) Eker rat uteri on PND 12 after a single exposure to 50mg/kg, 50�g/kg or 50ng/kg of BPA, DES (1mg/kg) or VEH for 6hrs. A) Western blot analysis revealed no significant activation of pS6 by BPA as compared to DES or VEH. B) Densitometry of western blots revealed no significant activation of the PI3K/AKT pathway. Data are represented as the average ratio of phopsho-AKT/AKT of three independent experiments.
Supplementary Table 2 from Expression of G Protein-Coupled Receptor 19 in Human Lung Cancer Cells Is Triggered by Entry into S-Phase and Supports G2–M Cell-Cycle Progression
Authors: Kastner Stefan , Voss Tilman , Keuerleber Simon , Glöckel Christina , Freissmuth Michael , Sommergruber Wolfgang
Published: April 2023

PDF file - 45K, Information about TaqMan assays used in RT-qPCR
Supplementary Figure 3 from Expression of G Protein-Coupled Receptor 19 in Human Lung Cancer Cells Is Triggered by Entry into S-Phase and Supports G2–M Cell-Cycle Progression
Authors: Kastner Stefan , Voss Tilman , Keuerleber Simon , Glöckel Christina , Freissmuth Michael , Sommergruber Wolfgang
Published: April 2023

PDF file - 88K, Gpr19 siRNA-induced increase in binucleated and polylobed nuclei
Supplementary Figure 1 from Expression of G Protein-Coupled Receptor 19 in Human Lung Cancer Cells Is Triggered by Entry into S-Phase and Supports G2–M Cell-Cycle Progression
Authors: Kastner Stefan , Voss Tilman , Keuerleber Simon , Glöckel Christina , Freissmuth Michael , Sommergruber Wolfgang
Published: April 2023

PDF file - 337K, Reduced cellular proliferation upon Gpr19 siRNA treatment. Thumbnail visualization of confluence measurement for NCI-H1703 cells and phase contrast microscopy pictures of NCI-H1703 and DMS 53 cells subject to siRNA transfection
Figure S4 from Tumor Endothelial Cell–Mediated Antigen-Specific T-cell Suppression via the PD-1/PD-L1 Pathway
Authors: Taguchi Kazuhiro , Onoe Takashi , Yoshida Tomoaki , Yamashita Yoshinori , Tanaka Yuka , Ohdan Hideki
Published: April 2023

Figure S4. PD-L1 expression in TECs was absent in syngeneic chimeric PD-L1 KO mice whose PD-L1-negative hematopoietic cells were replaced with PD-L1-positive cells from WT mice (right panel), while TECs in WT mice whose PD-L1-positive hematopoietic cells were replaced with PD-L1-positive cells from WT mice expressed PD-L1 (left panel).
Figure S3 from Tumor Endothelial Cell–Mediated Antigen-Specific T-cell Suppression via the PD-1/PD-L1 Pathway
Authors: Taguchi Kazuhiro , Onoe Takashi , Yoshida Tomoaki , Yamashita Yoshinori , Tanaka Yuka , Ohdan Hideki
Published: April 2023

Figure S3. CD4+ T cell purity after magnetic positive selection.
Figure S2 from Tumor Endothelial Cell–Mediated Antigen-Specific T-cell Suppression via the PD-1/PD-L1 Pathway
Authors: Taguchi Kazuhiro , Onoe Takashi , Yoshida Tomoaki , Yamashita Yoshinori , Tanaka Yuka , Ohdan Hideki
Published: April 2023

Figure S2. (A) Stimulation ratio and (B) specific killing formulas.
Figure S1 from Tumor Endothelial Cell–Mediated Antigen-Specific T-cell Suppression via the PD-1/PD-L1 Pathway
Authors: Taguchi Kazuhiro , Onoe Takashi , Yoshida Tomoaki , Yamashita Yoshinori , Tanaka Yuka , Ohdan Hideki
Published: April 2023

Figure S1. (A) Proliferation of OT-I CD8+ T cells induced by addition of OVA257-264-pulsed BMDCs. (B) High-dose OVA257-264-pulsed BMDCs stimulation abolished suppression of OT-I CD8+ T cell proliferation. (C) TECs failed to induce OT-I CD8+ T cell proliferation in the absence of stimulation with OVA257-264-pulsed BMDCs.
Supplementary Figure 4 from KRASG12D- and BRAFV600E-Induced Transformation of Murine Pancreatic Epithelial Cells Requires MEK/ERK-Stimulated IGF1R Signaling
Authors: Appleman Victoria A. , Ahronian Leanne G. , Cai JiuFeng , Klimstra David S. , Lewis Brian C.
Published: April 2023

PDF file - 270K, IGF and EGF family ligand expression in KRASG12D- and BRAFV600E-expressing PDECs
Supplementary Tables 1 - 2, Figures 1 - 2 from Enhanced Tumorigenic Potential of Colorectal Cancer Cells by Extracellular Sulfatases
Authors: Vicente Carolina M. , Lima Marcelo A. , Yates Edwin A. , Nader Helena B. , Toma Leny
Published: April 2023

Supplementary 1: Table 1 - Sequences of shRNA used in the study. Supplementary 2: Table 2 - Sequences of primers used in the study. Supplementary 3: mRNA level of SULFs after shRNA knockdown. Supplementary 4: mRNA expression of HS biosynthetic enzymes
Supplemental Figure and Table Legends from Enhanced Tumorigenic Potential of Colorectal Cancer Cells by Extracellular Sulfatases
Authors: Vicente Carolina M. , Lima Marcelo A. , Yates Edwin A. , Nader Helena B. , Toma Leny
Published: April 2023

Supplemental Figure and Table Legends
Supplementary Figure 1B from Kinin B2 Receptor Mediates Induction of Cyclooxygenase-2 and Is Overexpressed in Head and Neck Squamous Cell Carcinomas
Authors: Zhang Weiping , Bhola Neil , Kalyankrishna Shailaja , Gooding William , Hunt Jennifer , Seethala Raja , Grandis Jennifer R. , Siegfried Jill M.
Published: April 2023

PDF file - 13K
Supplementary Tables 1-2, Figures 1-5 from Genome-Wide Association and Fine Mapping of Genetic Loci Predisposing to Colon Carcinogenesis in Mice
Authors: Liu Pengyuan , Lu Yan , Liu Hongbo , Wen Weidong , Jia Dongmei , Wang Yian , You Ming
Published: April 2023

PDF file - 1MB
Supplementary Figure 1 from Inhibition of Eg5 Acts Synergistically with Checkpoint Abrogation in Promoting Mitotic Catastrophe
Authors: Chen Yue , Chow Jeremy P.H. , Poon Randy Y.C.
Published: April 2023

PDF file - 87K
Supplementary Figure Legend from Glutathione S-Transferase Mu2 Suppresses Cancer Cell Metastasis in Non–Small Cell Lung Cancer
Authors: Tang Sheau-Chung , Wu Chih-Hsien , Lai Chien-Hung , Sung Wen-Wei , Yang Wan-Jung , Tang Lee-Chun , Hsu Chung-Ping , Ko Jiunn-Liang
Published: April 2023

PDF file - 81K
Supplementary Figure 1 from Glutathione S-Transferase Mu2 Suppresses Cancer Cell Metastasis in Non–Small Cell Lung Cancer
Authors: Tang Sheau-Chung , Wu Chih-Hsien , Lai Chien-Hung , Sung Wen-Wei , Yang Wan-Jung , Tang Lee-Chun , Hsu Chung-Ping , Ko Jiunn-Liang
Published: April 2023

PDF file - 636K, Supplementary Figure 1. Expression was analyzed by RT-PCR of total RNA (2 μg) ampliﬁed by RT-PCR.
Supplementary Figure 1 from MUC1 Drives c-Met–Dependent Migration and Scattering
Authors: Horm Teresa M. , Bitler Benjamin G. , Broka Derrick M. , Louderbough Jeanne M. , Schroeder Joyce A.
Published: April 2023

PDF file - 4.3MB, PMIP treatment changes gene expression: List of genes upregulated or downregulated at least 3-fold upon PMIP treatment in BT20 breast cancer cells
Supplementary Figure Legend from MYC-Induced Epigenetic Activation of GATA4 in Lung Adenocarcinoma
Authors: Castro Inês C. , Breiling Achim , Luetkenhaus Katharina , Ceteci Fatih , Hausmann Simone , Kress Sebastian , Lyko Frank , Rudel Thomas , Rapp Ulf R.
Published: April 2023

PDF file - 88K
Supplementary Figures 1 - 4, Table 1 from p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma
Authors: Li Zhen , Sun Yin , Chen Xufeng , Squires Jill , Nowroozizadeh Behdokht , Liang Chaozhao , Huang Jiaoti
Published: April 2023

Supplementary Methods, Supplementary Figure legends. Primer sets for quantitative RT-PCR Supplementary Figure S1. A. Cell cycle analysis of LNCaP cells after expression of DNp53 at 48 hours. Cells were labeled with staining buffer containing PI (50 Î¼g/ml) and RNAse (100 Î¼g/ml), and then were analyzed by reading on LSRII cytometer at 488 nm. 25,000 events per sample were collected, and data were analyzed by FlowJo. B. Cell cycle analysis of PC-3 cells after expression of wild type p53 at 16, 24 and 32 hours. Cell cycle was analyzed as in A. C. miR-25 expression analysis after expression of wild type p53 at 16 and 24 hours using qRT-PCR. Supplementary Figure S2. A. Real time qRT-PCR was utilized to determine relative expression of Fbxw7 and Wwp2 in NE1.8 and PC-3 cells. Asterisks indicate significant differences (p<0.05). Supplementary Figure S3. Biological effects of miR-25 on cell proliferation and invasion in PC-3 cells. PC-3 cells transfected with miR inhibitor negative control or miR-25 inhibitor for 48 hours. A. For cell proliferation assay, cells were re-seeded in a 96-well plate in 100 Î¼l of culture medium at a density of 10,000 cells/well respectively. Every 24 hours after seeding, the cells were treated with WST reagent according to the instruction of the kit. Absorbance was measured at 420nm. B. For cell invasion assay, 20,000 cells were resuspended in culture medium containing 2% FBS, and re-seeded in 24-well invasion chamber respectively. After 24 hours, cells on the upper surface of the filters were removed with a cotton swab moistened with medium. The filters were fixed and stained with 0.5% crystal violet. Migrated cells were quantified by counting the numbers of cells that penetrated the membrane in four microscopic fields (viewed at 20Ã— magnification) per filter. Statistical significance was calculated using a student t-test as compared with control treatment: *, p<0.05; Supplementary Figure S4. A. Real time qRT-PCR for determination of relative expression of Aurka in NE1.8 and PC-3 cells. Asterisks indicate significant differences (p<0.05). B. Cycloheximide (CHX) chase assay for the half-life of AURKA. NE1.8 or PC-3 cells were transfected with control miR or miR-25 for 48 hours. Cells were then treated with CHX (20 Î¼g/ml) for the indicated hours, and Western blotting was performed. C. The level of remaining AURKA at different time points was quantified as the percentage of initial AURKA level (0 hour of CHX treatment).
Supplementary Data from Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism
Authors: Li Albert M. , Ducker Gregory S. , Li Yang , Seoane Jose A. , Xiao Yiren , Melemenidis Stavros , Zhou Yiren , Liu Ling , Vanharanta Sakari , Graves Edward E. , Rankin Erinn B. , Curtis Christina , Massagué Joan , Rabinowitz Joshua D. , Thompson Craig B. , Ye Jiangbin
Published: April 2023

Supplementary Data from Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism
Supplementary Table 2 from Regulation of Inflammatory Breast Cancer Cell Invasion through Akt1/PKBα Phosphorylation of RhoC GTPase
Authors: Lehman Heather L. , Van Laere Steven J. , van Golen Cynthia M. , Vermeulen Peter B. , Dirix Luc Y. , van Golen Kenneth L.
Published: April 2023

PDF file - 16K, PKB/Akt consensus sequences
Supplementary Figure Legends from Targeting Opsin4/Melanopsin with a Novel Small Molecule Suppresses PKC/RAF/MEK/ERK Signaling and Inhibits Lung Adenocarcinoma Progression
Authors: Wang Qiushi , Zhang Tianshun , Chang Xiaoyu , Wang Keke , Lee Mee-Hyun , Ma Wei-Ya , Liu Kangdong , Dong Zigang
Published: April 2023

Supplementary Figure Legends 1-5
Supplementary Figure 3B from Regulation of Inflammatory Breast Cancer Cell Invasion through Akt1/PKBα Phosphorylation of RhoC GTPase
Authors: Lehman Heather L. , Van Laere Steven J. , van Golen Cynthia M. , Vermeulen Peter B. , Dirix Luc Y. , van Golen Kenneth L.
Published: April 2023

PDF file - 47K, Expression of RhoC GTPase Akt-consensus sequence mutants do not affect SUM149 viability. Propidium iodide (PI) based apoptosis assay with the expression of RhoCS73D phosphomimetic mutant
Supplementary Figure 3A from Regulation of Inflammatory Breast Cancer Cell Invasion through Akt1/PKBα Phosphorylation of RhoC GTPase
Authors: Lehman Heather L. , Van Laere Steven J. , van Golen Cynthia M. , Vermeulen Peter B. , Dirix Luc Y. , van Golen Kenneth L.
Published: April 2023

PDF file - 50K, Expression of RhoC GTPase Akt-consensus sequence mutants do not affect SUM149 viability. Propidium iodide (PI) based apoptosis assay with the expression of RhoCS73A, which cannot be phosphorylated by Akt
Supplementary Figure Legends 1-3, Table from Alkylation Sensitivity Screens Reveal a Conserved Cross-species Functionome
Authors: Svilar David , Dyavaiah Madhu , Brown Ashley R. , Tang Jiang-bo , Li Jianfeng , McDonald Peter R. , Shun Tong Ying , Braganza Andrea , Wang Xiao-hong , Maniar Salony , Croix Claudette M. St , Lazo John S. , Pollack Ian F. , Begley Thomas J. , Sobol Robert W.
Published: April 2023

PDF file - 60K
Supplementary Dataset 5 from Alkylation Sensitivity Screens Reveal a Conserved Cross-species Functionome
Authors: Svilar David , Dyavaiah Madhu , Brown Ashley R. , Tang Jiang-bo , Li Jianfeng , McDonald Peter R. , Shun Tong Ying , Braganza Andrea , Wang Xiao-hong , Maniar Salony , Croix Claudette M. St , Lazo John S. , Pollack Ian F. , Begley Thomas J. , Sobol Robert W.
Published: April 2023

XLS file - 28K, Enriched genes identified by both NIH DAVID and Princeton GO Term Finder
Supplementary Table 1 from Identification of Genomic Targets of Transcription Factor Aebp1 and its role in Survival of Glioma Cells
Authors: Ladha Jayashree , Sinha Swati , Bhat Vasudeva , Donakonda Sainitin , Rao Satyanarayana M.R.
Published: April 2023

XLS file - 67K, List of Primers
Supplementary Table 2 from WNT7A Regulates Tumor Growth and Progression in Ovarian Cancer through the WNT/β-Catenin Pathway
Authors: Yoshioka Shin , King Mandy L. , Ran Sophia , Okuda Hiroshi , MacLean James A. , McAsey Mary E. , Sugino Norihiro , Brard Laurent , Watabe Kounosuke , Hayashi Kanako
Published: April 2023

PDF file - 52K
Supplementary Figure 1 from WNT7A Regulates Tumor Growth and Progression in Ovarian Cancer through the WNT/β-Catenin Pathway
Authors: Yoshioka Shin , King Mandy L. , Ran Sophia , Okuda Hiroshi , MacLean James A. , McAsey Mary E. , Sugino Norihiro , Brard Laurent , Watabe Kounosuke , Hayashi Kanako
Published: April 2023

PDF file - 2.9MB
Supplementary Methods, Figure 9, Movie Legends 1-3 from Constitutive K-RasG12D Activation of ERK2 Specifically Regulates 3D Invasion of Human Pancreatic Cancer Cells via MMP-1
Authors: Botta Gregory P. , Reginato Mauricio J. , Reichert Maximilian , Rustgi Anil K. , Lelkes Peter I.
Published: April 2023

PDf file - 1.1MB
Supplementary Figure 3 from Role of Plasminogen Activator Inhibitor-1 in Urokinase's Paradoxical In Vivo Tumor Suppressing or Promoting Effects
Authors: Jing Yuqi , Kovacs Krisztina , Kurisetty Vittal , Jiang Zhijie , Tsinoremas Nick , Merchan Jaime R.
Published: April 2023

PDF file - 1.6MB, qRT-PCR analysis of tumor cell derived uPA, VEGF-A, endothelin 1, CXCL-1 and IL-1 beta
Supplementary Figure 2 from Role of Plasminogen Activator Inhibitor-1 in Urokinase's Paradoxical In Vivo Tumor Suppressing or Promoting Effects
Authors: Jing Yuqi , Kovacs Krisztina , Kurisetty Vittal , Jiang Zhijie , Tsinoremas Nick , Merchan Jaime R.
Published: April 2023

PDF file - 1.7MB, Effects of tumor uPA overexpression on 4T1 tumor growth and lung metastases after primary tumor resection
Supplementary Figure 1 from Role of Plasminogen Activator Inhibitor-1 in Urokinase's Paradoxical In Vivo Tumor Suppressing or Promoting Effects
Authors: Jing Yuqi , Kovacs Krisztina , Kurisetty Vittal , Jiang Zhijie , Tsinoremas Nick , Merchan Jaime R.
Published: April 2023

PDF file - 1.7MB, In vitro Characterization of uPA overexpression
Supplementary Table 1 from The NSD2 p.E1099K Mutation Is Enriched at Relapse and Confers Drug Resistance in a Cell Context–Dependent Manner in Pediatric Acute Lymphoblastic Leukemia
Authors: Pierro Joanna , Saliba Jason , Narang Sonali , Sethia Gunjan , Saint Fleur-Lominy Shella , Chowdhury Ashfiyah , Qualls Anita , Fay Hannah , Kilberg Harrison L. , Moriyama Takaya , Fuller Tori J. , Teachey David T. , Schmiegelow Kjeld , Yang Jun J. , Loh Mignon L. , Brown Patrick A. , Zhang Jinghui , Ma Xiaotu , Tsirigos Aristotelis , Evensen Nikki A. , Carroll William L.
Published: April 2023

Cell line IC50 values
Figure S2 from Drug Targeting the Actin Cytoskeleton Potentiates the Cytotoxicity of Low Dose Vincristine by Abrogating Actin-Mediated Repair of Spindle Defects
Authors: Wang Yao , Stear Jeffrey H. , Swain Ashleigh , Xu Xing , Bryce Nicole S. , Carnell Michael , Alieva Irina B. , Dugina Vera B. , Cripe Timothy P. , Stehn Justine , Hardeman Edna C. , Gunning Peter W.
Published: April 2023

The combinations of anti-Tpm3.1 drugs and VCR show strong synergy in inducing apoptosis.
Supplementary Figure 3 from Genetic and Epigenetic Inactivation of Extracellular Superoxide Dismutase Promotes an Invasive Phenotype in Human Lung Cancer by Disrupting ECM Homeostasis
Authors: Teoh-Fitzgerald Melissa L.T. , Fitzgerald Matthew P. , Jensen Taylor J. , Futscher Bernard W. , Domann Frederick E.
Published: April 2023

PDF file - 374KB
Supplemental Figure S4AB from MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC
Authors: Alam Maroof , Ahmad Rehan , Rajabi Hasan , Kufe Donald
Published: April 2023

Supplemental Figure S4AB. A. H1299/CshRNA and H1299/MUC1shRNA cells were analyzed for let-7a-c miRNA levels by qRT-PCR. Results are expressed as relative let-7a-c levels (mean{plus minus}SD of three determinations) as compared to that obtained for CshRNA cells (assigned a value of 1). B. Lysates from H1299/CshRNA and H1299/MUC1shRNA cells were immunoblotted with the indicated antibodies.
Supplemental Figure S1 from MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC
Authors: Alam Maroof , Ahmad Rehan , Rajabi Hasan , Kufe Donald
Published: April 2023

Supplemental Figure S1. Lysates from H1650 cells stably expressing a control scrambled shRNA (CshRNA) or a MUC1 shRNA were immunoblotted with the indicated antibodies.
Supplementary Methods, Figures 1-2 from Ah Receptor Antagonism Represses Head and Neck Tumor Cell Aggressive Phenotype
Authors: DiNatale Brett C. , Smith Kayla , John Kaarthik , Krishnegowda Gowdahalli , Amin Shantu G. , Perdew Gary H.
Published: April 2023

PDF file - 469K, S1. Human epidermal keratinocytes fail to significantly express IL6 compared to HNSCC cells. S2. AHR ligands inhibit HN13 and HN2095 migration in agarose spot assay
Figure S2 from Mesothelin Enhances Tumor Vascularity in Newly Forming Pancreatic Peritoneal Metastases
Authors: Avula Leela Rani , Rudloff Michael , El-Behaedi Salma , Arons Danielle , Albalawy Rakan , Chen Xiongfong , Zhang Xianyu , Alewine Christine
Published: April 2023

In vivo BLI of mice inoculated IP with Luc/GFP+ KLM1 Mock or KO#2 on day 3 (D3), 7 (D7) and 14 (D14) post-injection.
Supplementary Table S6 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Authors: Camp J. Terese , Elloumi Fathi , Roman-Perez Erick , Rein Jessica , Stewart Delisha A. , Harrell J. Chuck , Perou Charles M. , Troester Melissa A.
Published: April 2023

Supplementary Table S6 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Supplementary Table S3 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Authors: Camp J. Terese , Elloumi Fathi , Roman-Perez Erick , Rein Jessica , Stewart Delisha A. , Harrell J. Chuck , Perou Charles M. , Troester Melissa A.
Published: April 2023

Supplementary Table S3 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Supplementary Table S2 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Authors: Camp J. Terese , Elloumi Fathi , Roman-Perez Erick , Rein Jessica , Stewart Delisha A. , Harrell J. Chuck , Perou Charles M. , Troester Melissa A.
Published: April 2023

Supplementary Table S2 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Supplementary Table S1 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Authors: Camp J. Terese , Elloumi Fathi , Roman-Perez Erick , Rein Jessica , Stewart Delisha A. , Harrell J. Chuck , Perou Charles M. , Troester Melissa A.
Published: April 2023

Supplementary Table S1 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Supplementary Figures 1-2 from IL-6 Promotes Head and Neck Tumor Metastasis by Inducing Epithelial–Mesenchymal Transition via the JAK-STAT3-SNAIL Signaling Pathway
Authors: Yadav Arti , Kumar Bhavna , Datta Jharna , Teknos Theodoros N. , Kumar Pawan
Published: April 2023

PDF file - 85K
Supplementary Data from 3-Phosphoinositide–Dependent Protein Kinase-1 Regulates Proliferation and Survival of Cancer Cells with an Activated Mitogen-Activated Protein Kinase Pathway
Authors: Lu Zhuomei , Cox-Hipkin Mary Ann , Windsor William T. , Boyapati Anita
Published: April 2023

Supplementary Data from 3-Phosphoinositide–Dependent Protein Kinase-1 Regulates Proliferation and Survival of Cancer Cells with an Activated Mitogen-Activated Protein Kinase Pathway
Supplementary Figure 5 from miR-31 Is a Broad Regulator of β1-Integrin Expression and Function in Cancer Cells
Authors: Augoff Katarzyna , Das Mitali , Bialkowska Katarzyna , McCue Brian , Plow Edward F. , Sossey-Alaoui Khalid
Published: April 2023

PDF file - 63K
Supplementary Figure 3 from miR-31 Is a Broad Regulator of β1-Integrin Expression and Function in Cancer Cells
Authors: Augoff Katarzyna , Das Mitali , Bialkowska Katarzyna , McCue Brian , Plow Edward F. , Sossey-Alaoui Khalid
Published: April 2023

PDF file - 19K
Supplementary Figure 2 from miR-31 Is a Broad Regulator of β1-Integrin Expression and Function in Cancer Cells
Authors: Augoff Katarzyna , Das Mitali , Bialkowska Katarzyna , McCue Brian , Plow Edward F. , Sossey-Alaoui Khalid
Published: April 2023

PDF file - 20K
Supplementary Figures S1-S2 from A Key Role for Early Growth Response-1 and Nuclear Factor-κB in Mediating and Maintaining GRO/CXCR2 Proliferative Signaling in Esophageal Cancer
Authors: Wang Bo , Khachigian Levon M. , Esau Luke , Birrer Michael J. , Zhao Xiaohang , Parker M. Iqbal , Hendricks Denver T.
Published: April 2023

Supplementary Figures S1-S2 from A Key Role for Early Growth Response-1 and Nuclear Factor-κB in Mediating and Maintaining GRO/CXCR2 Proliferative Signaling in Esophageal Cancer
Supplementary Figure S1 from The Pak4 Protein Kinase Plays a Key Role in Cell Survival and Tumorigenesis in Athymic Mice
Authors: Liu Yingying , Xiao Hang , Tian Yanmei , Nekrasova Tanya , Hao Xingpei , Lee Hong Jin , Suh Nanjoo , Yang Chung S. , Minden Audrey
Published: April 2023

Supplementary Figure S1 from The Pak4 Protein Kinase Plays a Key Role in Cell Survival and Tumorigenesis in Athymic Mice
Supplementary Data from p21 Expression Is Induced by Activation of Nuclear Nerve Growth Factor–Induced Bα (Nur77) in Pancreatic Cancer Cells
Authors: Lee Syng-Ook , Chintharlapalli Sudhakar , Liu Shengxi , Papineni Sabitha , Cho Sung Dae , Yoon Kyungsil , Safe Stephen
Published: April 2023

Supplementary Data from p21 Expression Is Induced by Activation of Nuclear Nerve Growth Factor–Induced Bα (Nur77) in Pancreatic Cancer Cells
Supplementary Tables 1-3, Figures 1-4 from High-throughput RNAi Screening Identifies a Role for TNK1 in Growth and Survival of Pancreatic Cancer Cells
Authors: Henderson Meredith C. , Gonzales Irma M. , Arora Shilpi , Choudhary Ashish , Trent Jeffrey M. , Von Hoff Daniel D. , Mousses Spyro , Azorsa David O.
Published: April 2023

Supplementary Tables 1-3, Figures 1-4 from High-throughput RNAi Screening Identifies a Role for TNK1 in Growth and Survival of Pancreatic Cancer Cells
Supplementary Figure 2 from SDF-1α Induces PDGF-B Expression and the Differentiation of Bone Marrow Cells into Pericytes
Authors: Hamdan Randala , Zhou Zhichao , Kleinerman Eugenie S.
Published: April 2023

PDF file - 254K
Supplementary Figures 1-4, Tables 1-2 from c-MYC Oncoprotein Dictates Transcriptional Profiles of ATP-Binding Cassette Transporter Genes in Chronic Myelogenous Leukemia CD34+ Hematopoietic Progenitor Cells
Authors: Porro Antonio , Iraci Nunzio , Soverini Simona , Diolaiti Daniel , Gherardi Samuele , Terragna Carolina , Durante Sandra , Valli Emanuele , Kalebic Thea , Bernardoni Roberto , Perrod Chiara , Haber Michelle , Norris Murray D. , Baccarani Michele , Martinelli Giovanni , Perini Giovanni
Published: April 2023

PDF file - 2651K
Supplementary Data from p120-Catenin Is Transcriptionally Downregulated by FOXC2 in Non–Small Cell Lung Cancer Cells
Authors: Mortazavi Fariborz , An Jiabin , Dubinett Steven , Rettig Matthew
Published: April 2023

Supplementary Data from p120-Catenin Is Transcriptionally Downregulated by FOXC2 in Non–Small Cell Lung Cancer Cells
Supplementary Figures 1-3, Tables 1-2 from Long-Range Epigenetic Silencing Associates with Deregulation of Ikaros Targets in Colorectal Cancer Cells
Authors: Javierre Biola M. , Rodriguez-Ubreva Javier , Al-Shahrour Fatima , Corominas Marina , Graña Osvaldo , Ciudad Laura , Agirre Xabier , Pisano David G. , Valencia Alfonso , Roman-Gomez Jose , Calasanz Maria Jose , Prosper Felipe , Esteller Manel , Gonzalez-Sarmiento Rogelio , Ballestar Esteban
Published: April 2023

PDF file - 273K
Supplementary Figure S1 from Activation of p38 Mitogen-Activated Protein Kinase Is Required for Death Receptor–Independent Caspase-8 Activation and Cell Death in Response to Sphingosine
Authors: Yoon Chang-Hwan , Kim Min-Jung , Park Moon-Taek , Byun Joo-Yun , Choi Young-Hyun , Yoo Hwan-Soo , Lee Yong-Moon , Hyun Jin-Won , Lee Su-Jae
Published: April 2023

Supplementary Figure S1 from Activation of p38 Mitogen-Activated Protein Kinase Is Required for Death Receptor–Independent Caspase-8 Activation and Cell Death in Response to Sphingosine
Supplementary Data from A Lipid-Modified Estrogen Derivative that Treats Breast Cancer Independent of Estrogen Receptor Expression through Simultaneous Induction of Autophagy and Apoptosis
Authors: Sinha Sutapa , Roy Sayantani , Reddy Bathula Surendar , Pal Krishnendu , Sudhakar Godeshala , Iyer Seethalakshmi , Dutta Shamit , Wang Enfeng , Vohra Pawan Kumar , Roy Karnati Rammohan , Reddanna Pallu , Mukhopadhyay Debabrata , Banerjee Rajkumar
Published: April 2023

Supplementary Data from A Lipid-Modified Estrogen Derivative that Treats Breast Cancer Independent of Estrogen Receptor Expression through Simultaneous Induction of Autophagy and Apoptosis
Supplementary Data from Leucine Leucine-37 Uses Formyl Peptide Receptor–Like 1 to Activate Signal Transduction Pathways, Stimulate Oncogenic Gene Expression, and Enhance the Invasiveness of Ovarian Cancer Cells
Authors: Coffelt Seth B. , Tomchuck Suzanne L. , Zwezdaryk Kevin J. , Danka Elizabeth S. , Scandurro Aline B.
Published: April 2023

Supplementary Data from Leucine Leucine-37 Uses Formyl Peptide Receptor–Like 1 to Activate Signal Transduction Pathways, Stimulate Oncogenic Gene Expression, and Enhance the Invasiveness of Ovarian Cancer Cells
Supplementary Figure Legend from miR-200 Inhibits Lung Adenocarcinoma Cell Invasion and Metastasis by Targeting Flt1/VEGFR1
Authors: Roybal Jonathon D. , Zang Yi , Ahn Young-Ho , Yang Yanan , Gibbons Don L. , Baird Brandi N. , Alvarez Cristina , Thilaganathan Nishan , Liu Diane D. , Saintigny Pierre , Heymach John V. , Creighton Chad J. , Kurie Jonathan M.
Published: April 2023

PDF file - 34K
Supplementary Figure 1 from miR-200 Inhibits Lung Adenocarcinoma Cell Invasion and Metastasis by Targeting Flt1/VEGFR1
Authors: Roybal Jonathon D. , Zang Yi , Ahn Young-Ho , Yang Yanan , Gibbons Don L. , Baird Brandi N. , Alvarez Cristina , Thilaganathan Nishan , Liu Diane D. , Saintigny Pierre , Heymach John V. , Creighton Chad J. , Kurie Jonathan M.
Published: April 2023

PDF file - 49K
Supplementary Table S1 from Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes
Authors: Hu Xiaolan , Stern Howard M. , Ge Lin , O'Brien Carol , Haydu Lauren , Honchell Cynthia D. , Haverty Peter M. , Peters Brock A. , Wu Thomas D. , Amler Lukas C. , Chant John , Stokoe David , Lackner Mark R. , Cavet Guy
Published: April 2023

Supplementary Table S1 from Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes
Supplementary Figure 1 from Inhibition of DNA-Dependent Protein Kinase Induces Accelerated Senescence in Irradiated Human Cancer Cells
Authors: Azad Arun , Jackson Susan , Cullinane Carleen , Natoli Anthony , Neilsen Paul M. , Callen David F. , Maira Sauveur-Michel , Hackl Wolfgang , McArthur Grant A. , Solomon Benjamin
Published: April 2023

PDF file - 43K, BEZ235 inhibits phosphorylation of PI3K/mTOR. Western blot showing phospho-AKT (Ser473) and phospho-S6 (Ser235/236) expression in serum-starved H460 and A549 cells treated with indicated doses of BEZ235 and stimulated with IGF-1 (100 ng/ml).
Supplementary Table 1, Figures 1-3 from EphB4 Promotes Site-Specific Metastatic Tumor Cell Dissemination by Interacting with Endothelial Cell–Expressed EphrinB2
Authors: Héroult Mélanie , Schaffner Florence , Pfaff Dennis , Prahst Claudia , Kirmse Robert , Kutschera Simone , Riedel Maria , Ludwig Thomas , Vajkoczy Peter , Graeser Ralph , Augustin Hellmut G.
Published: April 2023

Supplementary Table 1, Figures 1-3 from EphB4 Promotes Site-Specific Metastatic Tumor Cell Dissemination by Interacting with Endothelial Cell–Expressed EphrinB2
Supplementary Data from Skp2 Directs Myc-Mediated Suppression of p27Kip1 yet Has Modest Effects on Myc-Driven Lymphomagenesis
Authors: Old Jennifer B. , Kratzat Susanne , Hoellein Alexander , Graf Steffi , Nilsson Jonas A. , Nilsson Lisa , Nakayama Keiichi I. , Peschel Christian , Cleveland John L. , Keller Ulrich B.
Published: April 2023

Supplementary Data from Skp2 Directs Myc-Mediated Suppression of p27Kip1 yet Has Modest Effects on Myc-Driven Lymphomagenesis
Supplementary Data from Clusterin Facilitates COMMD1 and I-κB Degradation to Enhance NF-κB Activity in Prostate Cancer Cells
Authors: Zoubeidi Amina , Ettinger Susan , Beraldi Eliana , Hadaschik Boris , Zardan Anousheh , Klomp Leo W.J. , Nelson Colleen C. , Rennie Paul S. , Gleave Martin E.
Published: April 2023

Supplementary Data from Clusterin Facilitates COMMD1 and I-κB Degradation to Enhance NF-κB Activity in Prostate Cancer Cells
Supplementary Data from Smad3 Is a Key Nonredundant Mediator of Transforming Growth Factor β Signaling in Nme Mouse Mammary Epithelial Cells
Authors: Dzwonek Joanna , Preobrazhenska Olena , Cazzola Silvia , Conidi Andrea , Schellens Ann , van Dinther Maarten , Stubbs Andrew , Klippel Anke , Huylebroeck Danny , ten Dijke Peter , Verschueren Kristin
Published: April 2023

Supplementary Data from Smad3 Is a Key Nonredundant Mediator of Transforming Growth Factor β Signaling in Nme Mouse Mammary Epithelial Cells
Supplementary Figures S1-S3 from Generation of a Transgenic Mouse for Colorectal Cancer Research with Intestinal Cre Expression Limited to the Large Intestine
Authors: Xue Yingben , Johnson Robert , DeSmet Marsha , Snyder Paul W. , Fleet James C.
Published: April 2023

Supplementary Figures S1-S3.
Supplementary Data from The MDM2-A Splice Variant of MDM2 Alters Transformation In vitro and the Tumor Spectrum in Both Arf- and p53-Null Models of Tumorigenesis
Authors: Volk Erin L. , Fan Liying , Schuster Katja , Rehg Jerold E. , Harris Linda C.
Published: April 2023

Supplementary Data from The MDM2-A Splice Variant of MDM2 Alters Transformation In vitro and the Tumor Spectrum in Both Arf- and p53-Null Models of Tumorigenesis