bluuebunny/crossref_metadata_2025 huggingface dataset:
Sosialisasi Sosial Media Marketing Untuk Meningkatkan Pengetahuan Digital Marketing kepada Santri Pondok Pesantren Al-Muhajirin III Jombang
Authors: Mariam Dewi , Raharjdo Raden Johnny Hadi
Published: February 2025

Di era digital yang terus berkembang, kemampuan memanfaatkan media sosial sebagai alat pemasaran menjadi sangat penting, termasuk bagi para santri di pondok pesantren. Pondok Pesantren Al-Muhajirin III memiliki potensi besar dalam mengembangkan santri menjadi pengusaha, namun masih terdapat kendala dalam penguasaan keterampilan kewirausahaan dan manajemen, khususnya dalam aspek pemasaran. Keterbatasan program pendidikan bisnis dan pembatasan penggunaan teknologi menghambat pengembangan keterampilan kewirausahaan, terutama dalam pemasaran digital. Untuk mengatasi masalah ini, dilakukan program sosialisasi social media marketing dengan fokus pada penggunaan Instagram. Program ini melibatkan empat tahap utama: observasi, persiapan, pelaksanaan, dan evaluasi. Observasi dilakukan untuk mengidentifikasi tingkat pengetahuan santri mengenai pemasaran digital, yang kemudian digunakan sebagai dasar untuk menyusun materi yang relevan. Tahap pelaksanaan melibatkan pemaparan konsep dasar pemasaran digital, strategi konten di Instagram, analisis studi kasus, dan diskusi interaktif. Sesi ini dirancang untuk memberikan pemahaman mendalam tentang pentingnya pemasaran digital dan cara memanfaatkan Instagram sebagai alat pemasaran. Santri diajak untuk aktif berpartisipasi melalui kuis dan diskusi, sehingga materi dapat diserap secara optimal. Hasil evaluasi menunjukkan keberhasilan program ini dalam meningkatkan pemahaman santri tentang pemasaran digital. Santri dapat memahami konsep dasar social media marketing, mengidentifikasi jenis konten yang menarik, serta menganalisis strategi pemasaran dari berbagai studi kasus. Dengan program ini, santri diharapkan mampu memanfaatkan media sosial untuk mendukung usaha mereka di masa depan, sekaligus mempersiapkan diri menghadapi tantangan dunia digital yang terus berkembang.
Retail energy prices, exchange rate and food price inflation in Nigeria: SVAR Approach
Authors: Akidi Victor , Ikue Nenubari John
Published: February 2025

Food prices in Nigeria have experienced significant increases due to rising fuel costs, unstable exchange rates, and socio-political challenges. This study examines the effects of fuel prices and exchange rate changes on food inflation using a Structural Vector Autoregressive (SVAR) model, which provides insights into both immediate and long-term impacts. Monthly data from June 2015 to May 2024 shows a stable long-term relationship between food inflation, energy prices, and exchange rates, making it clear that these factors are key drivers of inflationary trends in Nigeria. Our findings reveal that increases in fuel prices, particularly for petrol and diesel, drive up the cost of food production and transportation, with noticeable impacts appearing within three to six months. Similarly, shifts in exchange rates raise the cost of imported foods, with effects becoming evident in about two to ten months. Recent economic reforms, such as the fuel subsidy removal in 2023, have intensified inflationary pressures, exposing structural weaknesses in Nigeria’s food supply chain, including poor infrastructure and insecurity. The study recommended a direct approach to tackle food inflation, we recommend the creation of a Food Price Stabilization Fund (FPSF), which would help manage extreme price volatility caused by energy price fluctuations and exchange rate changes among others.
O Nazismo como ardil
Authors: Campos de Oliveira Roberson
Published: February 2025

The aim of this article is to demonstrate that the terms fascist, Nazi, neo-fascist and other similar variations do not apply to the far right in Brazil. To this end, it situates the phenomenon historically, highlights the imperial nature of the ideology and program of Nazi-fascism and states that the main ideological and programmatic elements of Nazi-fascism are organically linked to and conditioned by the strategic imperial objectives of the ideology and program. The total impossibility of associating Nazi-fascism with right-wing extremists in Brazil stems from the fact that the various right-wing extremist factions in the country have as their strategic objective neocolonial reconversion, the consummation of a reprimarized vassal state, subject to the designs of the American empire.
Editorial nº 12 - Crise do capital, nações e territórios conflagrados
Authors: Aguerri Borges da Silva Ana Carolina , Marcondes Miglioli Aline , Da Rocha Soares Layza , Lopes Faggiano Daniel , Editores Os
Published: February 2025

This edition reflects on how contemporary capitalism intensifies social and environmental inequalities, exacerbating conflicts on a global scale. The reflections presented cover topics such as the struggle for land, social resistance, regional wars, and the impact of forced migrations, in addition to investigating the correlation between the climate crisis and the predatory exploitation of natural resources. Given this scenario, the aim is not only to understand the destructive forces of capital but also to highlight emancipatory initiatives of traditional peoples and communities, whose knowledge and practices offer paths to resistance and social justice.
Neuroinflamação e Depressão
Authors: Bittencourt Amaral Caroline , Clara Speziali Menegazzi Almeida Ana , Silva Ferreira Henrique , Cury Cardoso de Padua Thiago
Published: February 2025

Introdução: A neuroinflamação tem se mostrado um fator crucial na compreensão da depressão, uma condição que afeta cerca de 264 milhões de pessoas em todo o mundo, conforme dados da Organização Mundial da Saúde .A relação entre inflamação e saúde mental é um campo de pesquisa crescente, que busca entender como os processos inflamatórios podem influenciar a gravidade e a resposta ao tratamento da depressão. Objetivo: Este estudo tem como objetivo analisar a intersecção entre neuroinflamação e depressão, enfatizando a importância dos biomarcadores inflamatórios na patogênese da depressão e na potencialização de intervenções terapêuticas. Metodologia: Foi realizada uma revisão narrativa utilizando a plataforma PubMed, com a estratégia de busca "Inflammation OR neuroinflammation AND depression OR mood disorders AND anti-inflammatory agents". Foram aplicados filtros para restringir a busca a artigos de ensaios clínicos, ensaios clínicos randomizados, revisões e revisões sistemáticas com metanálise, publicados entre 2019 e 2025. Após a triagem inicial de 142 estudos, 19 artigos foram selecionados para análise detalhada. Resultados: A ativação de células gliais, como microglia e astrócitos, e a liberação de citocinas inflamatórias, como interleucina-6 (IL-6) e fator de necrose tumoral alfa (TNF-α), desempenham papéis significativos na gravidade dos sintomas depressivos. Níveis elevados de biomarcadores inflamatórios, como a proteína C-reativa (PCR), estão associados a uma maior severidade dos sintomas, sugerindo que a avaliação desses marcadores pode ser útil na estratificação de pacientes e na personalização do tratamento. Conclusão: A identificação de biomarcadores inflamatórios é promissora para o aprimoramento do diagnóstico e do manejo da depressão, indicando que intervenções anti-inflamatórias podem melhorar os resultados clínicos. A compreensão do papel da neuroinflamação na depressão não apenas enriquece o conhecimento sobre sua fisiopatologia, mas também abre novas possibilidades para o desenvolvimento de terapias direcionadas, contribuindo assim para a saúde mental global.
PENGUATAN KOMPETENSI LITERASI DALAM PEMBELAJARAN PJOK KEBUGARAN JASMANI DI SMAN 1 WONOAYU SIDOARJO
Authors: Wijono  , Yuri Lolita  , Shery Iris Zalillah  , Wiriawan Oce , Ilo Raditio Wiriawan
Published: February 2025

Guru sebagai pendidik mempunyai peran yang sangat penting dalam mengarahkan proses dan tujuan pembelajaran di kelas. Tujuan pembelajaran memerlukan arah yang jelas guna mencapai tujuan pendidikan yang telah dirancang. Seiring berjalannya waktu, kualitas pembelajaran diharapkan semakin meningkat menyesuaikan dengan perkembangan zaman. Kurang beraktifitas fisik mengakibatkan adanya penurunan daya kemampuan yang bukan hanya terjadi pada peserta didik, tapi juga pada pendidik (guru). Pada dasarnya menekankan kepekaan terhadap dua hal: (1) peningkatan kesadaran terhadap persamaan hak, tanggung jawab, dan kesempatan yang sama antara laki-laki dan perempuan; (2) peningkatan kesadaran untuk mengangkat martabat masyarakat dan kemandirian individu--dari semua kelompok sosial--sebagai modal untuk mencapai kualitas hidup yang lebih baik. Tujuan pelaksanaan pengabdian di SMAN 1 Wonoayu Sidoarjo ini adalah untuk memberikan wawasan dan pengetahuan tentang pentingnya penguatan literasi dan gesi yang mengarah pada peningkatan kualitas pembelajaran yang literat dan ramah. Adapun yang menjadi sasaran pelatihan adalah guru SMAN 1 Wonoayu Sidoarjo dengan berfokus pada rencana pelaksanaan pembelajaran (RPP) atau modul ajar mereka yang menggunakan strategi literasi. Melalui aktivitas pengabdian kepada masyarakat, Unesa dengan guru di SMAN 1 Wonoayu dapat memberikan manfaat bagi pengembangan kompetensi guru secara berkelanjutan. Penguatan dilaksanakan dengan metode pelatihan secara intensif dengan melibatkan partisipasi aktif guru guna meningkatkan kualitas pembelajaran. PKM dilaksanakan selama 5 bulan.
PENGABDIAN MASYARAKAT SOSIALISASI DAN IMPLEMENTASI APLIKASI JANGAN TERONG DI KANTOR KECAMATAN WINONG
Authors: Arifviando Muhammad Villa , Supriyono
Published: February 2025

Pelayanan administrasi publik yang efisien menjadi kebutuhan penting dalam meningkatkan kualitas layanan kepada masyarakat. Kantor Kecamatan Winong menghadapi tantangan dalam proses administrasi, yang sering kali memakan waktu dan sumber daya. Melalui kegiatan Pengabdian Masyarakat ini, diperkenalkan aplikasi digital Jangan Terong, yang dirancang khusus untuk meningkatkan efisiensi pelayanan di kecamatan winong. Aplikasi Jangan Terong memungkinkan masyarakat untuk mengajukan berbagai layanan, seperti pembuatan Kartu Keluarga (KK) baru atau perubahan data, pembuatan Kartu Tanda Penduduk (KTP), serta layanan pindah penduduk secara digital. Hasil dari implementasi aplikasi ini menunjukkan peningkatan efisiensi waktu dan akurasi dalam pemrosesan data administrasi, serta meningkatkan kepuasan masyarakat terhadap pelayanan kecamatan. Dengan demikian, aplikasi Jangan Terong memberikan solusi praktis bagi peningkatan pelayanan publik di Kecamatan Winong.
Strategic planning as a tool for managing the economic behavior of an enterprise
Authors:   Simon Kuznets Kharkiv National University of Economics, Vlasenko Tetiana , Miroshnyk Oleksii ,   Kharkiv National University, Herasymchuk Oleksandr ,   Odesa National University of Technology
Published: February 2025

The article examines strategic planning as a tool for managing an enterprise’s economic behavior in the dynamic development of a market economy and the high uncertainty of the external environment. The relevance of using strategic planning to increase the competitiveness of enterprises, ensure their stability, and adapt to changing market conditions is determined. In the research process, modern theoretical approaches to strategic planning are analyzed. Factors influencing the economic behavior of an enterprise are systematized, among which the role of the external environment (economic, political, social factors) and internal resources of the enterprise (organizational structure, corporate culture, human resources) are highlighted. The key stages of the strategic planning process are determined: mission formation, analysis of the internal and external environment, strategy development, economic justification, implementation, and control over the achievement of the set goals. The importance of the long-term orientation of strategic planning, a systematic approach to making management decisions, innovative orientation, and involvement of stakeholders is substantiated. Measures for effectively implementing enterprise strategies are proposed, including adapting the organizational structure, personnel development, change, and risk management. In addition, the article builds a structural and logical scheme of strategic planning as a tool for managing the economic behavior of an enterprise, which reflects the sequence of planning stages, the relationship between key elements of the process, and mechanisms for implementing the strategy. This scheme allows you to visualize the logic of forming and implementing strategic decisions, ensuring consistency of actions at all levels of management. As a result of the study, it was concluded that strategic planning is a key tool for managing the economic behavior of an enterprise, which allows for the efficient use of resources, increasing competitiveness, and ensuring long-term sustainable development.

Keywords: strategic planning, enterprise economic behavior, management decisions, long-term goals, innovative development, strategic analysis, change management, economic stability.
Analysis on Food Munch Responsive website for restaurant menus
Authors: Mandari Vinitha , Y Veeranjaneyulu  , Siva Prasad B Veera Venkata , Nimmakayala Firdosh , Kumar MNK Bharath
Published: February 2025

The research is an innovative online food ordering platform designed to streamline the food ordering process with a focus on convenience, user engagement, and flexibility. This responsive website offers a wide range of features aimed at enhancing the user experience, including a recipe maker, QR code scanner, and a unique pre booking option. The recipe maker allows users to explore and customize dishes according to their preferences, while the QR code scanner provides quick access to restaurant menus and exclusive offers. The pre-booking option enables users to schedule their orders in advance, ensuring timely preparation and delivery. Additionally, the website includes expense management features that allow users to monitor their food expenses effectively, promoting budget-friendly ordering habits with a responsive design, the platform adapts seamlessly to various devices, providing a consistent and intuitive experience on desktops, tablets, and mobile phones. FOOD MUNCH offers a reliable and user-friendly solution for managing food orders, simplifying the process while catering to modern consumers' on-the-go lifestyle. Keywords: Online Food Ordering, Recipe Maker, Pre-booking Option, Responsive Web Design, UserFriendly Interface, Real-time Menu, Browsing Customer Reviews.
Analisis Persepsi Konsumen Terhadap Produk Kuliner Pindang Meranjat
Authors: Karo Karo Pelliyezer
Published: February 2025

Penelitian persepsi konsumen terhadap Pindang Meranjat ini dilakukan di lokasi asal dimana produk kuliner ini bermula yaitu Kabupaten Ogan Ilir, Provinsi Sumatera Selatan. Penelitian dilakukan dengan pendekatan kuantitatif melalui empat variabel organoleptic yaitu warna, aroma, tekstur dan rasa, pada tiga bagian utama produk pindang yaitu lauk, kuah dan kondimen, dengan total 12 indikator. Data primer dikumpulkan melalui kuesioner dari 55 responden yang terdiri dari 49 konsumen yang melakukan konsumsi ulang pindang (re-purchasement) dan 6 orang ahli. Metode yang digunakan adalah Importance Performance Analysis, terdiri atas pendekatan Indeks Tingkat Kesesuaian dan pemetaan melalui diagram kartesius. Hasil penelitian menunjukkan dari empat variabel, teridentifikasi variabel warna menjadi satu-satunya variabel yang memenuhi rerata tingkat persepsi dan tingkat ekspektasi konsumen; variabel aroma merupakan variabel yang tidak memenuhi kedua tingkat tersebut; dan dua variabel lainnya, tekstur dan rasa hanya memenuhi tingkat ekspektasi. Lebih lanjut, diketahui tiga indikator yang menjadi prioritas utama perbaikan kualitas produk Pindang Meranjat, secara berurutan berdasarkan skala prioritas tertinggi yaitu perbaikan terhadap tekstur kuah, rasa kuah dan aroma lauk dari produk dimaksud. Variabel susulan yang berpotensi berikutnya dalam meningkatkan kualitas adalah perbaikan pada tekstur kondimen. Melalui hasil ini, diharapkan dapat menjadi dasar perbaikan terstruktur agar kualitas produk Pindang Meranjat meningkat dalam rangka memenuhi ekspektasi konsumen sebagai produk kuliner asli yang berpotensi menjadi wisata kuliner dari Kabupaten Ogan Ilir.
EDUKASI LATIHAN JALAN TANDEM PADA LANSIA UNTUK MENINGKATKAN KESEIMBANGAN TUBUH DAN MENGURANGI RESIKO JATUH
Authors: Yusriana Yusriana , Kontesa Meria , Nurleny  , Afrizal
Published: February 2025

Jatuh adalah ancaman terbesar bagi kesehatan dan kemandirian lansia diatas 60 tahun dan merupakan penyebab kematian dikalangan usia tersebut. Kejadian jatuh dilaporkan sangat tinggi pada lansia diatas 65 tahun, tercatat 25-38% orang dan hampir sepertiga lansia pernah mempunyai pengalaman jatuh yang berakibat cidera serius.
Berdasarkan hasil survey yang dilakukan di RW X Kelurahan Korong Gadang Wilayah Kerja Puskesmas Kuranji Kota Padang pada tanggal 14 Oktober 2024, didapatkan 7 dari 10 orang lansia mengalami resiko gangguan keseimbangan. Salah satu terapi yang telah terbukti dapat memperbaiki keseimbangan tubuh lansia adalah salah satunya yaitu dengan latihan jalan tandem yang dapat melatih kekuatan otot yang mulai lemah. Jalan tandem (tandem stance) merupakan salah satu jenis latihan keseimbangan (balance exercise) yang melibatkan proprioseptif terhadap kestabilan tubuh.
Tujuan pelaksanaan pengabdian kepada masyarakat edukasi latihan jalan tandem adalah melatih kekuatan otot lansia untuk meningkatkan keseimbangan tubuh dan mengurangi resiko jatuh.
Um roedor exótico em uma ilha protegida: estimando a abundância do mocó (Kerodon rupestris) em Fernando de Noronha, Brasil
Authors: Micheletti Tatiane , Mangini Paulo Rogerio , P. O. Gasparotto Vinícius
Published: February 2025

Compreender a estrutura e dinâmica populacional de espécies exóticas é fundamental para avaliar seu potencial nível de ameaça aos ambientes nativos e planejar, se necessário, seu manejo. Esse conhecimento é obtido por meio da estimativa dos parâmetros populacionais. No entanto, em ambientes insulares, especialmente em países em desenvolvimento, a logística, o custo e certas características das espécies podem dificultar a coleta de dados, resultando em conjuntos de dados esparsos. O presente estudo teve como objetivo fornecer uma estimativa preliminar da probabilidade de sobrevivência e da abundância do mocó (Kerodon rupestris; Caviidae: Rodentia) na ilha de Fernando de Noronha por meio de dados esparsos. Usando um modelo de efeitos mistos log-normais de Poisson truncado em zero (ZPNE), primeiramente estimamos o número de indivíduos em uma colônia de K. rupestris (a colônia Boldró). Usando a densidade calculada (número de indivíduos dividido pela área da colônia) e informações sobre colônias mapeadas coletadas por meio de imagens de satélite, calculamos o tamanho da população da ilha. O modelo ZPNE apresentou uma probabilidade média de sobrevivência de 0,5499 em 185 dias e uma probabilidade média de captura de 0,858. A extrapolação das estimativas de tamanho da população da colônia de Boldró (21; IC95% 12 - 36 indivíduos) sugere que a população de mocós em Fernando de Noronha consiste em 5.473 (IC95% 3.114 - 9.622) indivíduos. Mesmo com dados limitados e cautela justificada, o presente estudo preliminar avaliou os parâmetros populacionais dessa população insular de K. rupestris, contribuindo com informações valiosas para o planejamento de seu manejo pela primeira vez.
TINJAUAN YURIDIS KETENTUAN UPAH PEKERJA/BURUH BERDASARKAN UNDANG UNDANG CIPTA KERJA PASCA PUTUSAN MAHKAMAH KONSTITUSI NOMOR 168/PUU-XXI/2023
Authors: Puspita Shinta Novia , Permana Yana Sukma
Published: February 2025

Negara Indonesia sebagai negara hukum yang telah menyatakan bahwa Pembangunan nasional dilaksankan dalam rangka pembangunan manusia Indonesia seutuhnya dan pembangunan masyarakat Indonesia seluruhnya untuk mewujudkan masyarakat yang sejahtera, adil, makmur, yang merata, baik materil maupun spiritual berdasarkan Pancasila dan UUD 1945. Sejalan dengan pernyataan tersebut maka Pemerintah Indonesia sangat menaruh perhatian yang serius salah satunya dalam bidang ketenagakerjaan. Upaya untuk memberikan kepastian hukum dan berjalannya hubungan industrial yang harmonis, dinamis dan berkeadilan dengan membuat peraturan perundang-undangan serta ketentuan-ketentuan untuk mencapai tujuan hubungan industrial di Indonesia. Beberapa peraturan perundang-undangan telah diberlakukan bahkan telah mengalami perubahan, termasuk UU No 13 Tahun 2003 sebagai UU induk ketenagakerjaan saat ini telah dilakukan perubahan dengan UU Ciptakerja. Perkembangan terakhir telah diberlakukan UU No 6 Tahun 2023 tentang Penetapan Peraturan Pemerintah No 2 Tahun 2022 tentang Cipta Kerja menjadi Undang-undang. Terhadap UU No 6 telah ada Putusan MK No 168/PUU-XXI/202. Adapun rumusan masalah di dalam penulisan ini adalah bagaimana pengaturan upah pekerja/buruh pasca Putusan Mahkamah Konstitusi Nomor 168/PUU-XXI/2023. Metode yang digunakan dalam penulisan ini adalah Yuridis Normatif. Dengan adanya putusan MK maka PP yang mengatur tentang Upah Pekerja/Buruh harus segera dibuat oleh pemerintah yang harus mengakomodir segala yang berhubungan dengan Upah Pekerja/Buruh.
Analisis Implementasi Kebijakan Mal Pelayanan Publik di Indonesia
Authors: Ariyanti Aprilia Dwi , Simanjuntak Jenius Hakim , Jafar Muhammad Iqbal , Nugroho Redo
Published: February 2025

Public service is an essential element in governance that aims to meet the needs of the community effectively. One of the significant innovations in Indonesia is the Public Service Mall (Mal Pelayanan Publik/MPP), which is an integrated service that integrates various types of services from the central government, local governments, business entities, and private sector in one location. Based on Presidential Regulation Number 89 of 2021, MPP aims to improve efficiency, accessibility, and quality of services, as well as encourage bureaucratic reform towards good governance. The implementation of MPP shows a positive impact in the form of reducing bureaucracy, time and cost efficiency, and increasing regional competitiveness. Vice President Ma'ruf Amin has given directions to implement MPP in all districts and cities. However, challenges still exist, such as institutional conditions both in terms of the One-Stop Investment and Integrated Services Agency (Dinas Penanaman Modal dan Pelayanan Satu Pintu/DPMPTSP) as the MPP coordinator and the service provider by organizations at the MPP, limited human resources, funding, and not all data between services are integrated. The analysis was conducted using a literature study method with data sources from books, journal articles that specifically discuss MPP in terms of policy implementation, legislative documents, reports, and other relevant sources and validated through interviews with the authors of the study related to the implementation of the MPP. The analysis was conducted using Grindle's policy implementation theory which combines the content of policy and the context of implementation, showing that the success of MPP is influenced by institutional support, commitment of related actors, adequate resources and must adjust to the conditions in which MPP policies are implemented. To ensure sustainability, institutional improvement, budget optimization, comprehensive evaluation, and the development of digital MPP as a future innovation are required. After implementing strategic steps, MPP has the potential to become a breakthrough solution in improving public services in Indonesia.
Pregnancy-Triggered Severe Lupus Nephritis with Pleural Effusion: A Case Report
Authors: Zaki Mahmudi Dasril  , Deka Viotra
Published: February 2025

Background: Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), characterized by kidney inflammation. Pregnancy can trigger or exacerbate LN due to hormonal shifts and altered immune responses. This case highlights the challenges in diagnosing and managing pregnancy-associated LN.
Case presentation: A 27-year-old woman presented with anasarca, malar rash, shortness of breath, and foamy urine during her first pregnancy. She had a history of SLE with previous symptoms limited to skin and joint involvement. Investigations revealed nephrotic-range proteinuria, hematuria, elevated creatinine, and positive anti-nuclear antibodies (ANA). Renal biopsy confirmed Class IV lupus nephritis. She was diagnosed with pregnancy-triggered severe LN with nephrotic syndrome, pleural effusion, and a hypercoagulable state. Treatment included high-dose corticosteroids and mycophenolate mofetil, with close monitoring of both maternal and fetal health.
Conclusion: This case underscores the importance of recognizing and promptly managing LN in pregnancy. Early diagnosis, multidisciplinary care, and individualized treatment are crucial to optimize maternal and fetal outcomes.
A Detailed Comparative Analysis Towards Longer Terms Traffic Loads Forecasting with Autoregressive Integrated Moving Average (ARIMA/SARIMA) Models to Improve Transportation Services
Authors: Pengili Boris , Karras Dimitrios A.
Published: February 2025

Traffic flow forecast will be a great help in life of big cities citizens, especially in a time where road system cannot handle rush hours loads without constraining citizen to wait in traffic line and the population is in growth. The dataset used was captured by loop detectors that evaluate speeds length, time etc. In this paper, ARIMA and SARIMA were the models built for the prediction of the number of cars consisting of the traffic load. Although this study has been conducted for Tirana city, the methodology and discussions should be relevant to any big city. First, we transformed the time series to stationary with log scale transformation. After that, we found the right parameters for our models. Then we compared the results of two models: ARIMA (which we built with auto-Arima) and SARIMA, where Arima had the best outcome for the given dataset. The results were very satisfactory and with the Arima model we can make accurate forecasts for at least 3 months, showing that not only short-term forecasts are possible but even longer-term traffic load forecasting might be viable.
Practice makes perfect, especially when doing what we like
Authors: Reppa Irene , McDougall Siné
Published: February 2025

Previous research has found that aesthetic appeal can facilitate visual search performance. One avenue of enquiry is that appealing icons are processed better than unappealing icons. If appealing stimuli are better processed, then it may be expected that they will benefit from practice more than their unappealing counterparts. In the current study (N = 100) we examined the effect of stimulus appeal on visual search performance. Half of the participants searched for appealing icons first, followed by unappealing icons, and the order was reversed for the other half. First, visual search performance benefited from stimulus appeal, and specifically the interaction of stimulus appeal and complexity – visual stimulus appeal led to better search performance but only for stimuli that were visually complex, with no effect of appeal for visually simple stimuli. Second, task experience benefited appealing icons more than unappealing icons. These results extend current knowledge of the status of visual aesthetic appeal on performance. They provide new evidence that appealing stimuli benefit from practice and are easier to learn compared to their unappealing counterparts.
Non-alcoholic fatty liver disease and osteoporosis: a bi-directional association
Authors: Dudinskaya E. N. , Onuchina Yu. S.
Published: February 2025

Osteoporosis is a serious public health concern worldwide, characterized by decreased bone mineral density (BMD) and impaired microarchitecture of bone tissue, leading to an increased incidence of low-trauma fractures. Osteoporosis typically affects older adults, but it can also occur at younger ages due to impaired absorption of calcium and vitamin D in various gastrointestinal (GI) diseases. NAFLD is a risk factor for decreased bone mineral density (BMD). New data on the pathophysiological changes in bone tissue in NAFLD are presented: release of inflammatory cytokines, decreased secretion of molecules directly affecting bone (strengthening bone) from the liver affected by NAFLD, impaired vitamin D metabolism, and impaired intestinal microbiota. NAFLD is a risk factor for decreased BMD.

Further research is needed to confirm the physiological significance of NAFLD with regard to the risk of osteoporotic bone fractures. Mandatory osteoporosis screening and bone health monitoring in patients with NAFLD may be possible in future NAFLD management strategies and guidelines.
Relationship between cardiovascular risk in older women and parameters of mammograms obtained as part of a medical examination
Authors: Dolgushin G. O. , Plisyuk A. G. , Yarovaya E. B. , Tsurskaya D. D. , Filichkina E. M. , Mershina E. A. , Sinitsyn V. E. , Ivlev O. E. , Orlova Ya. A.
Published: February 2025

BACKGROUND. Validation of the SCORE2 scale in the Russian population showed high accuracy in assessing cardiovascular risk (CVR) in men, but not in women. The development of new methods for assessing CVR in women is therefore an urgent task. A number of mammographic parameters, such as breast calcification (BC) and breast density (BD) can be additional biomarkers of cardiovascular diseases in women.

AIM. To assess the relationship between the results of a retrospective analysis of mammograms and CVR in women aged 65 years and older.

MATERIALS AND METHODS. Retrospective analysis involved the mammograms of 570 patients who subsequently underwent medical examinations at the Research and Educational Center of the Moscow State University. BD and BC were assessed based on scales developed by the American College of Radiology. The CVR was assessed in accordance with the Guidelines of the Russian Society of Cardiology. Statistical analysis was performed using the open-source R 4.1 environment.

RESULTS. A relationship was found between mammographic parameters and CVR in women aged 65 years and older. Low BD, the presence and prevalence of BC were associated with higher CVR. The vascular type of calcifications was typical for patients with high and very high CVR. The absence of statistically significant differences in the density and calcification between the right and left mammary glands will be considered when developing an integral marker to verify the obtained results.

CONCLUSIONS. A method for secondary analysis of preventive mammography data can help assess the CVR and determine rational routing of patients within the framework of the second stage medical examination. Downward reclassification of cardiovascular risk factors will help avoid unnecessary prescription of statins, while upward reclassification will help prescribe optimal treatment and provide additional motivation for women to correct cardiovascular risk factors.
Eğitim Yöneticilerinin Yönetim Süreçlerinde Kaygı ve Tutumları
Authors: Demirogları Burcu
Published: February 2025

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Beyond symmetric self-assembly and effective molarity: unlocking functional enzyme mimics with robust organic cages
Authors: Andrews Keith G
Published: February 2025

The bespoke environments in enzyme active sites can selectively accelerate chemical reactions by as much as 1019. Macromolecular and supramolecular chemists have been inspired to understand and mimic these accelerations and selectivities for applications in catalysis for sustainable synthesis. Over the past 60+ years, mimicry strategies have evolved with changing interests, understanding, and synthetic advances but, ubiquitously, research has focused on use of a molecular “cavity”. The activities of different cavities vary with the subset of features available to a particular cavity type. Unsurprisingly, without synthetic access to mimics able to encompass more/all of the functional features of enzyme active sites, examples of cavity-catalyzed processes demonstrating enzyme-like rate accelerations remain rare. This perspective will briefly highlight some of the key advances in traditional cavity catalysis, by cavity type, in order to contextualize the recent development of robust organic cage catalysts, which can exploit stability, functionality, and reduced symmetry to enable promising catalytic modes.
Percepción de la Atención Materna Integral en la Mujer Embarazada Durante el Trabajo de Parto, Nacimiento y Puerperio, en la UMAE 48, de León, Guanajuato
Authors: Davalos Vega Cinthia Elizabeth , Luna Anguiano José Luis Felipe , Sosa Bustamante Gloria Patricia , Patricia González Alma
Published: February 2025

Antecedentes: El nacimiento es un proceso natural donde es fundamental que el personal de salud otorgue una atención integral. Objetivo: Analizar la percepción de la atención materna integral en la mujer embarazada durante el trabajo de parto, nacimiento y puerperio. Material y métodos: Estudio prospectivo, observacional, longitudinal y analítico. Incluyeron mujeres de 18 años a 45 años, con embarazo único de 37 semanas o más, sin comorbilidades o discapacidad. Se realizaron cuatro cuestionarios (características demográficas, ansiedad, escala numérica del dolor y encuesta de satisfacción).Resultados: Se analizaron 332 embarazadas, la mediana de edad fue 26 años. Las primigestas presentaron mayor grado de ansiedad (p=0.030), así como aquellas pacientes en que inició el trabajo de parto con medicamento (p=021). Cuando se aplicó conducción con oxitócicos presentaron mayor grado de dolor OR de 2.6 (IC95%1.64-4.14), así como realización de episiotomía OR 3.2 (IC95%1.92-5.47), a diferencia, la aplicación de analgesia obstétrica es factor protector (p=0.024). Conclusión: La satisfacción global en la atención obstétrica fue buena satisfacción, donde resalta el acudir a curso psicoprofiláctico disminuye el grado de dolor percibido y mayor satisfacción en la atención obstétrica.
COMPARISON OF TOTAL FLAVONOID CONTENT AND ANTIOXIDANT ACTIVITY OF PURPLE LEAF EXTRACT (Graptophyllum pictum (L.) Griff.) USING MACERATION AND SOXHLETATION EXTRACTION METHODS
Authors: Darotulmutmainnah Azmi , Marini Marini , Herliningsih Herlingsih , Handayani Hana
Published: February 2025

Purple leaves in Indonesia can be used as an anti-inflammatory medication and laxative to treat hemorrhoids, rheumatism, boils, and skin diseases. Purple leaves are also used as free-radical antidotes. This was due to the presence of secondary metabolite compounds in purple leaves. The right extraction method determines the amount of flavonoids that can be extracted and achieves a high flavonoid content. This study aimed to determine the total flavonoid content and antioxidant activity of purple leaves using different extraction methods, namely maceration and Soxhletation. This study employed an experimental method of testing total flavonoid levels using UV-Vis spectrophotometry and antioxidant activity using the DPPH method. The results showed that the maceration method yielded a total flavonoid level of 4,422 ± 0,047 ppm, which was higher than that obtained using the Soxhletation method (1,547 ± 0,027 ppm). In the antioxidant activity test, vitamin C was used as a comparator, with an IC50 of 2.263 ppm (very strong). The IC50 of purple leaf extract using the maceration method was 123,32 ppm (medium), while the soxhletation method yielded an IC50 of 104,42 ppm (medium). This shows that vitamin C has more potent antioxidant activity in counteracting free radicals than purple leaf extract, using maceration and Soxhletation methods. The  results showed a significant difference in total flavonoid levels using different extraction methods, while there was no significant difference in the antioxidant activity of purple leaf extract using maceration and  Soxhletation methods.
 
Keywords: antioxidant, extraction, flavonoid, maceration, purple leaf, soxhletation
Prevalence of non-genital warts generated by human papillomaviruses and role of interleukins IL10, IL17, and hematological parameters
Authors:   Department of Microbiology, College of Medicine, Thi-Qar University, Thi-Qar, Iraq, Mahdi Haider , Shallal Mohammed Jasim Mohammed ,   Department of Microbiology, College of Medicine, Thi-Qar University, Thi-Qar, Iraq, Naif Alaa Abdul Hasan ,   Department of Dermatology, College of Medicine, University of Thi-Qar, Iraq
Published: February 2025

Background. The Human papillomaviruses (HPVs) are among the most prevalent human infections, with a spectrum of skin-related symptoms ranging from benign warts to malignant carcinomas. Warts, characterized by verrucous and exophytic lesions, result from HPV infection of basal keratinocytes. This study aimed to investigate IL-10, IL-17, and certain hematological parameters in patients with cutaneous warts. Method. The study was conducted between August 2023 and January 2024, involving 103 patients aged 8–60 years, all diagnosed with cutaneous warts. Molecular detection was performed using polymerase chain reaction (PCR). Blood samples were collected from both the patient group and healthy controls for complete blood count (CBC) analysis using automated hematology analyzers. Serum samples were also examined for IL-10 and IL-17 levels. Results. Skin warts caused by HPV were clinically diagnosed through dermatologist examination. Of the 103 patients, 59 were male (57.28%) and 44 were female (42.72%), aged 8–60 years. Fifty healthy controls – 26 males (52%) and 24 females (48%), ages 10–58 years – were included. The mean serum IL-10 level among patients with HPV infection was 11.2 ± 5.37 pg/ml, significantly higher than the healthy controls (6.22 ± 2.0 pg/ml, p < 0.001). Similarly, IL-17 levels were also significantly elevated in patients (23.9 ± 7 pg/ml) compared to controls (12.3 ± 3.2 pg/ml, p < 0.001). Conclusion. Serum levels of IL-10 and IL-17 were notably higher in individuals with HPV infection compared to healthy controls. IL-10 promotes an immunosuppressive state and contributes to wart development, while IL-17 may influence the persistence and pathogenesis of viral warts.
Advantages of ICG-guided laparoscopic resection in complicated diverticulitis: a narrative literature review
Authors:   Faculty of Medicine, Medical University - Sofia, Sofia, Bulgaria, Yordanov Nikolay Y.
Published: February 2025

More than 10% of cases of acute diverticulitis may require surgical intervention. Despite the high morbidity and mortality rates, Hartmann's operation has been considered the “gold standard” in the treatment of complicated diverticulosis with peritonitis for many years. Contemporary treatment recommendations define laparoscopy as the method of choice for Hinchey stages II and III, allowing for laparoscopic resection with primary anastomosis, as well as laparoscopy with drainage. The inflammatory syndrome causes disruption of microcirculation and affects the trophicity of the intestinal wall, ultimately leading to the compromise of the anastomosis. The use of indocyanine green (ICG) angiography allows for the assessment of circulation and the prevention of severe complications. The use of ICG for visualization of the ureters also reduces the risk of iatrogenic lesions.
A systematic review of case series of Marfan syndrome: ocular findings and complications
Authors:   Faculty of Medicine, Hang Tuah University, Surabaya, East Java, Indonesia, Adji Arga Setyo , Billah Atiyatum ,   Faculty of Medicine, Hang Tuah University, Surabaya, East Java, Indonesia, Fadila Firzaniattu ,   Faculty of Medicine, Hang Tuah University, Surabaya, East Java, Indonesia, Praja Echa Titiani ,   Faculty of Medicine, Hang Tuah University, Surabaya, East Java, Indonesia, Retno Indira ,   Department of Ophthalmology, Dr. Ramelan Navy Hospital, Surabaya, East Java, Indonesia, Puspitasari Angela ,   Department of Emergency Medicine, Dr. Ramelan Navy Hospital, Surabaya, East Java, Indonesia, Angel Syalomitha Claudia Stefani ,   Faculty of Medicine, Hang Tuah University, Surabaya, East Java, Indonesia
Published: February 2025

Background. Marfan syndrome (MFS) is a genetic disorder affecting connective tissue, with ocular complications being a significant cause of morbidity. Understanding the range of ocular manifestations and outcomes in MFS patients is crucial for improving clinical management. This systematic review evaluated case series documenting ocular findings and complications in individuals with MFS. Methods. A systematic review was conducted following PRISMA guidelines. Studies were retrieved from Google Scholar, PubMed, and ScienceDirect. A total of 4,205 records were screened, and 19 studies were included for analysis. This review focused on case series describing MFS patients with ocular manifestations such as glaucoma, cataracts, retinal detachment, and other complications. Data on patient characteristics, diagnoses, therapeutic interventions, and outcomes were extracted and synthesized. Results. The included studies reported diverse ocular complications in MFS patients, including glaucoma (e.g., pigmentary glaucoma and phacogenic glaucoma), cataracts (e.g., dislocated crystalline lenses), retinal detachment, coloboma, and strabismus. Common therapies include beta-blockers, pars plana vitrectomy, lens extraction, and femtosecond laser-assisted cataract surgery. Clinical outcomes varied, with many patients achieving improved intraocular pressure control and visual acuity posttreatment. Notably, timely surgical intervention, such as pars plana vitrectomy, is critical for favorable visual outcomes in severe cases of retinal detachment. Conclusion. MFS is associated with a wide range of ocular complications, many of which require surgical intervention. Early diagnosis and tailored management strategies are essential for preserving vision and enhancing the quality of life in these patients. Further research is needed to establish standardized treatment protocols and long-term outcomes.
Relevancy of blood specimen-molecular biomarkers in studying osteoporosis in postmenopausal women
Authors:   Department of Microbiology, College of Medicine, University of Basrah, Iraq, Dawood Bassam , Ali Naael H. ,   Department of Microbiology, College of Medicine, University of Basrah, Iraq, Al-Ali Shereen ,   Department of Pathological Analyses, College of Science, University of Basrah, Iraq
Published: February 2025

Background. Osteoporosis is a bone disease characterized by low bone mass and micro-architectural weakening of bone tissue. It can be influenced, in part, by immunological activity. Therapeutically targeting immune factors that promote osteoporosis could protect a larger number of susceptible individuals, especially postmenopausal women, from this debilitating disease. The aim of the present study is to evaluate blood levels of gene expression for RANKL, RANK, OPG, OSCAR, and the transcription factors RORᵧt and FOXP3 (as representatives of Th17 and Treg cells, respectively) to determine their potential as biomarkers for detecting postmenopausal osteoporosis. Methods. A total of 88 postmenopausal women were included in this study: 43 women with osteoporosis (PO group), 45 women without osteoporosis (PNO group) as age-matched controls, and 40 young healthy females as baseline controls (YA group). Blood samples were collected from all participants to assess gene expression levels of the factors of interest using qRT-PCR. Results. There was a non-significant increase in RANKL expression in the PO group compared to the PNO and YA groups (PO=1.68, PNO=1.53, YA=1.0). The Th17 population was significantly elevated in the PO group compared to the YA group (PO=1.53, YA=1.0). No statistical differences were observed among the groups for the other genes. Conclusion. Th17 is a prominent osteoclastogenic marker detected in the blood. Although RANKL is a crucial factor in bone resorption, its expression level in the blood of postmenopausal women with osteoporosis appears to be inconclusive.
Pemanfaatan Data Spasial dalam Edukasi Daya Dukung Lingkungan bagi Siswa SMA Negeri 1 Tilamuta: Membangun Kesadaran Generasi Muda untuk Pembangunan Berkelanjutan
Authors: Maryati Sri , Merlin Merlin , Mokoginta Melani , Mayang Rohmila
Published: February 2025

The decline in environmental carrying capacity due to land use changes and population pressure poses a challenge to sustainable development. Boalemo Regency has diverse physical conditions, making environmental carrying capacity education essential for the younger generation. This activity aims to enhance students' spatial literacy using spatial data. The methods employed include material delivery, thematic map simulations using Geographic Information Systems (GIS), discussions, and evaluations through pre-test and post-test. Evaluation results indicate an improvement in students' understanding, with topographical condition indicators increasing from 5% to 100% and hydrological condition indicators from 15% to 95%. Spatial data simulations have proven effective in enhancing conceptual understanding and students' critical thinking skills. These results contribute to raising environmental awareness among the younger generation to support sustainable development policies.
Peningkatan Penguatan Branding dan Transparansi Melalui Pengembangan Sistem Informasi Website
Authors: Supriadi Sudawan , Wahyuni Sri , Siregar Dwi Rayana , Ulfah Fadilla , Santoso Ridwan
Published: February 2025

Strengthening branding and transparency is a strategic step for the University of Jambi Economics Education Study Program to increase competitiveness and public trust. In the digital era, the development of informative, interactive, and responsive websites is an urgent need to strengthen the image of the institution, attract prospective students, and build stakeholder loyalty. This service activity aims to design and develop a website-based information system that is user-friendly and transparent. The methods used include needs analysis, modern design development, internal training, and socialization to the academic community. The results show that the website developed is able to improve data accessibility, provide an optimal user experience, and present the latest information in real-time. This has an impact on improving academic reputation, user trust, and relationships with stakeholders. The integration of digital technology is a strategic model in building trust and credibility in a competitive higher education environment.
Peningkatan Aspek Percaya Diri Anak Usia Dini Melalui Kegiatan Market Day
Authors: Aliyah Nur , Anugrah Yuwan Fijar , Enjang Enjang
Published: February 2025

Self-confidence in early childhood is important to develop, because at this stage children are still in the process of building self-concept and independence. Lack of self-confidence can hinder their social, emotional, and cognitive development. This Market Day activity was carried out as an effort to improve the quality of learning practices related to self-confidence aspects in order to support optimal child development outcomes by being packaged through interesting and fun activities. The method used is Participant Action Research (PAR) which emphasizes the active involvement of participants in each stage of implementation in order to produce real changes in the community. The subjects in this community service activity were 21 children from students of SPS Melati II, Margasari Village. The results of this community service journal are that Market Day is an effective method in increasing self-confidence for early childhood at SPS Melati II, Margasari Village, as evidenced by changes in behavior, namely children becoming more open in interacting with peers, not feeling embarrassed when meeting new people and, daring to speak in public.
A fogyatékkal élő fogvatartottak fogdai befogadásának jogi aggályai
Authors: Tóth Izabella
Published: February 2025

In his study, the author explores the problems of accommodating prisoners with disabilities.
A kábítószerrel visszaélés bűncselekmény nyomozásának sajátosságai
Authors: Varga Péter
Published: February 2025

In this article, the author describes the specificities of the investigation of drug abuse offences.