bluuebunny/crossref_metadata_2025 huggingface dataset:
Binding Affinity of 17-b-ethinylestradiol to Normal and Mutant Types of Estrogen Receptors An in silico evaluation
Authors: Cheverasan Adelina , Mioc Marius , Simu Sebastian , Soica Codruta , Dehelean Cristina , Szasz Florin , Navolan Dan , Poenaru Marioara
Published: February 2020

Estrogen receptors (ERs)are nuclear transcription factor receptorsthat play important roles in gene expression and cell cycle regulation. Because of their ligand-activated signaling implication in carcinogenesis,ERs are extensively researched as protein targets for anti-cancer drug discovery active in certain types of tumors. However, a major drawback is the emergence of wild type tumors withoverexpressed mutant variants of ER, which become resistant to estrogen inhibitor drugs. Herein we studied the binding mode and affinity of the semisynthetic estrogen agonist, 17-b-estradiol (E2) in normal and mutant variants of ERs, by means of molecular docking. Our results showed a small decrease in binding affinity, recorded in mutant variants of ERa and a change in the binding interactions formed when the compound wasdocked in an agonist-bound conformation of the ERa . Nevertheless we concluded that even if the binding affinity showed a small decrease in the case of mutant type receptors,E2 potency towards ER�won�t register a downward trend.
Corrosion Resistance of Injection-casting Dental Implants
Authors: Szota Michal , Lukaszewicz Adrian
Published: February 2020

In this paper the results of corrosion resistance for dentistry implants � commercial and produced by injection casting were presented. The produced and commercial implants were made from the same material (Ti6Al4V ELI). Studies were carried out on six samples: two were input materials (E1, E2), two were commercial implants (C1, C2) and two were produced implants (P1, P2) where P1 was produced from input material E1 and P2 was produced from input material E2. For corrosion resistance potentiodynamic studies were carried out. It was found that produced samples through injection casting have better corrosion resistance than commercial implants. However, produced implants have similar corrosion resistance to input materials. The studies have shown that it is possible to use innovative injection casting to improve corrosion resistance of dental implants.
The Impact of Biochar on the Soil
Authors: Rusanescu Carmen Otilia , Murad Erol , Jinescu Cosmin , Rusanescu Marin
Published: February 2020

In the present paper are presented the experimental results of biomass gasification, the biochair was produced from vineyards by controlled pyrolysis at 750 �C, in order to increase the fertility of soils, it was found the increase of the fertility produced by the development of the vegetables in the soil to which was added biochar. Soil was added to soil 4 g/dm3 biochar, 8 g/dm3 biochar, the soil had no high humidity, was taken at a time when it had not rained for at least one week, the soil pH was 8, in the soil with 8 g/dm3 biochar the plants increased compared to the soil with 4 g/dm3 and the soil without biochar. The biochar resulting from pyrolysis and gasification processes is a valuable amendment to agricultural soils and an efficient and economical way to seize carbon. Using biochar it is possible to increase the diversity of agricultural land in an environmentally sound way in areas with depleted soils, limited organic resources and insufficient water for development. Helps to soil carbon sequestration with negative CO2 balance, increases the productive potential of agricultural ecosystems.
Correlations Between Biochemical Profile and Echocardiographic Parameters in Patients with Cirrhosis of the Liver Without Previous Cardiovascular Abnormalities
Authors: Costache Irina Iuliana , Garleanu Irina , Mitu Ovidiu , Ion Adriana , Darie Amalia , Namat Razan Al , Miftode Radu Stefan , Costache Dan Alexandru , Iliescu Dan
Published: February 2020

The role of cardiac imaging in the management of non-cardiovascular diseases has been continuously increased. Most studies suggest the utility of echocardiography examination in the evaluation of left ventricular function in cirrhotic patients, being well-known that cirrhosis of the liver is associated with cardiovascular abnormalities which include especially left ventricle diastolic dysfunction and left ventricular hypertrophy. Cardiac dysfunction contributes to morbidity and mortality associated with liver transplantation. The aim of this study was to emphasize the role of echocardiography in assessing left ventricular systolic and diastolic function in cirrhotic patients in order to establish a correlation between echocardiography parameters and biochemical variables in patients with end-stage cirrhosis. The study was conducted as a cross-sectional analysis over a two-year period (2016-2018). 41 patients with cirrhotic liver from the departments of Gastroenterology and Cardiology from St Spiridon Emergency Hospital of Ia�i were included in the study, after a written informed consent was obtained. Patients with any previous cardiovascular (CV) abnormalities, other causes of pulmonary hypertension and endocrinopathies were excluded from the study. Using transthoracic echocardiography left ventricle dimensions and wall thickness (left ventricle posterior wall thickness + interventricular septum thickness) and also diastolic function (E wave, A wave, E/A ratio, deceleration time of E wave) and systolic function (ejection fraction) were determined along with biochemical variables. In conclusion, no significant association was obtained between echocardiographic changes and biochemical profile in patients with cirrhosis of liver.
Arthroscopic Equipment Used in the Treatment of Calcaneal Spurs A case presentation
Authors: Moga Marius , Pogarasteanu Mark Edward , Edu Antoine
Published: February 2020

Calcaneal spurs are a common cause of heel pain, discomfort and difficulty in walking and in athletic activities. Often they are associated with plantar fasciitis. The first line of treatment is non-surgical, but often this fails. Although many surgeons prefer the open or mini-open approaches, a growing number of orthopedic specialists are starting to use surgical tools initially designed for arthroscopy in order to treat this pathology. The initial technique was developed by a group of surgeons from the Orthopedic Service of Hospital Hermanos Ameijeiras in Havana, Cuba. This technique involves approaching the heel with an arthroscopic camera and a shaver, creating a chamber around the spur, releasing the plantar fascia and using a burr to eliminate the spur. The surgical tools are borrowed from arthroscopy, but the technique is in fact endoscopic. This only proves that the tools and methods developed in arthroscopic surgery can be extended and used in other areas of orthopedic surgery. We discussed the recent international literature, in order to evaluate the number of reported cases, the surgical technique variations and the outcomes. We looked at patient characteristics (age, sex, comorbidities), outcome measuring tools employed (for example the Budiman-Mak foot function index) and results after surgery, including healing time and complications. We aim to draw a conclusion, based on published results and taking into account as many reported cases as available, in regards to the use of arthroscopic tools in the endoscopic treatment of calcaneal spurs.
Soil Chemical Pollution and Aggressive Pathologies
Authors: Morariu Stelian Ioan , Duceac Letitia Doina , Luca Alina Costina , Popescu Florina , Pavel Liliana , Gavrilescu Cristina Maria
Published: February 2020

Maintaining the soil in optimal parameters is vital for mankind, given its essential role in providing the alimentary base, as well as its extremely slow formation and regeneration (hundreds or thousands of years). The direct and indirect pollution of the soil and especially its chemical pollution represent a corollary of other types of pollution, given that it is produced by solid, liquid and gaseous residues. It may be involved in a wide range of diseases (respiratory, cardiovascular, digestive, renal, haematological, osteoarticular, neurological) of allergic, infectious, degenerative or neoplastic nature, from infancy to the old age. Although there are natural causes of soil pollution (e.g. volcanic eruptions), most pollutants come from human activities, which are the most incriminated in its pollution, degradation and erosion at an accelerated pace. The growing concern of all nations for the adoption of measures to limit the chemical pollution of the soil is partially found so far in viable and effective solutions intended to combat soil contamination and degradation and ensure its restoration. Chemical industrialization leads to technical and scientific progress, but at the same time it can develop related pathologies, which means that the role of the occupational health physician is essential in ensuring prophylaxis and the early detection of occupational diseases. Besides that, the role of the pediatrician is equally precious for the detection of specific diseases caused by chemical pollutants to children, because they will develop into adults with pathological stigma.The chemical pollution of the soil is a major challenge for ecologists, given that it is an important risk factor for many types of afflictions. It requires maximum attention from civil society, health care professionals and government institutions. The specialist in occupational medicine, as well as the pediatrician bear an essential responsibility in both, prevention and treatment.
Cardiopulmonary Testing and Biochemical Profile of Coronary Patients Subject to Cardiovascular Recovery Programs
Authors: Vasilcu Teodor Flaviu , Statescu Cristian , Sascau Radu , Roca Mihai , Costea Claudia Florida , Zota Madalina , Bararu Iris , Leon Constantin Maria , Mitu Florin
Published: February 2020

Cardiopulmonary exercise testing (CPET) has become the golden standard in the assessment of exercise capacity and intensity of the patients who are performing cardiac rehabilitation. The purpose of our study was to objectify the relationships between the parameters of CPET and the lipid profile after the cardiovascular rehabilitation. We found a significant increase in oxygen consumption (VO2) values, anaerobic threshold, effort capacity and maximum heart rate and an improvement in the lipid profile, marking a reduced cardiovascular risk.
Development of Single-step Protocols for the Separation of Naphtodianthrones from St. John�s Wort Extracts
Authors: Ionescu Elena , Iordache Tanta Verona , Tebrencu Carmen Elena , Cretu Ruxandra Mihaela , Florea Ana Mihaela , Radu Anita Laura , Zaharia Anamaria , Sarbu Andrei
Published: February 2020

St. John s Wort (SJW) or Hypericum perforatum L. is a therapeutic plant highly used in pharmacology. Recent in vivo anti-cancer action of naphtodianthrones (NTs) has extended the research related to enrichment methodologies of SJW phyto-extracts. Therefore, the presented study pursuits the optimization of single-step extraction methodologies to obtain NTs-rich extracts from SJW.
The Quality of Underwater Supplies in Western Romania
Authors: Hodisan Sorin , Badea Gabriela Elena , Bungau Simona , Sebesan Mioara , Melinte (Frunzulica) Carmen Elena , Popa Maria , Tit Delia Mirela
Published: February 2020

Over the last three decades, many scientist, national and international agencies were concerned about pollution of the Romanian environment, especially water and its impact on human health. This research includes studies and interpretations resulting from chemical and bacteriological analyzes of water samples collected from wells or underground springs from central north-western part of Romania. The water parameters were determined using standard analytical methods: pH, turbidity, oxidability, ammonium, nitrates, nitrites, chlorides, total hardness, conductivity, mesophilic heterotrophic microorganisms, coliforms, E. coli, intestinal enterococci. Regarding non-compliant samples, the main problem is the bacterial load of water, confirming domestic pollution sources of water. More than 50% of the analyzed samples, which had concentrations of nitrate over 10 mg/L were also found bacteriological inappropria
Assessment of the Antioxidant Effect of Ethanolic Extracts Obtained from Agrimonia eupatoria L., Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench Collected from the Estern Part of Romania
Authors: Gurita (Ciobotaru) Valentina Gabriela , Pavel Ioana Zinuca , Poenaru Marioara , Moaca Elena Alina , Florescu Sorin , Danciu Corina , Dumitrascu Victor , Imbrea Ilinca , Pop Georgeta
Published: February 2020

Numerous plants are currently used for both their curative and preventive effects in a wide range of pathologies. They possess multiple beneficial effects, including the well-known antioxidant capacity. Agrimonia eupatoria L. and Filipendula spp., from the Rosaceae family have emerged as a potential source of phenolic constituents, showing antioxidant activities. The aim of this study was to obtain ethanolic extracts from Agrimonia eupatoria L., Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench. collected from the West part of Romania and to determine their antioxidant capacity. Two DPPH assays were used to determine the antioxidant activity of the extracts, ethanolic solution of 1 and 0.1 mM DPPH. Our data indicated that all the extracts, regardless of the place of harvest possess significant antioxidant activity. The most potent activity was recorded for the extracts prepared from Agrimonia eupatoria L. collected from Bazia� � Locva Mountains in mixture with ethanolic solution of 0.1 mM DPPH, followed by Filipendula ulmaria (L.) Maxim, using the same concentration of ethanolic solution of standard antioxidant.
The Importance of Alcohol Testing by Gas Chromatography vs the Cordebard Classical Method Modified in the Medico Legal Investigation
Authors: Dumbrava Dan Perju , Radu Carmen Corina , David Sofia , Iov Tatiana , Iov Catalin Jan , Sandu Ion , Bulgaru Iliescu Diana
Published: February 2020

Considering the growing number of requests from the criminal investigations authorities addressed to the institutions of legal medicine, testing of blood alcohol concentration both in the living person and in the corpse, we believe that a presentation of the two methods which are used in our country, is a topic of interest at present. The purpose of this article is to provide the reader with the technical details on how blodd alcohol concentration is realised by means of the gas chromatographic method and the classical one, (Cordebard modified by D. Banciu and I. Droc) respectively. Another purpose of this article is to also show, in a comparative way, the elements that make the gas chromatographic method superior to the former one.
Spectral Properties of HEMA/poly(HEMA) as Ligand in Luminescent Europium Based Complexes Through Computational Investigation
Authors: Bacaita Elena Simona , Stan Corneliu Sergiu , Agop Maricel , Cioca Gabriela
Published: February 2020

This paper investigates, through computational methods, the spectral properties of (2-hydroxy ethyl) methacrylate used as ligand in a luminescent complex based on europium, aiming to show that the absorption spectra is determined by the ligand type and the emission spectra is specific for each lanthanide.
5-Hydroxytriptamine and Skeleton Influence Clinical Study
Authors: Albulescu Dana Maria , Carsote Mara , Ionovici Nina , Ghemigian Adina , Popescu Mihaela , Tuculina Mihaela Jana , Dascalu Ionela Teodora , Preda Smaranda Adelina , Tirca Tiberiu , Petrescu Mihai Sever , Bataiosu Marilena , Bechir Edwin Sever
Published: February 2020

5-hydroxytryptamine (5-HT) dually influences skeleton status through positive, indirect central effect and negative, direct, gut-associated impact. Circulating form is usually tested via venous blood sample. A limited number of clinical studies are published on this specific topic. We introduce a cross-sectional study on menopausal women with normal (N=29) and low bone mineral density (N=32) based on lumbar Dual-Energy X-Ray Absorptiometry (DXA) to whom serum serotonin was assessed and found no correlation with bone loss. This aspect confirms conflicting published data regarding the relationship between circulating levels and fracture risk assessment.
Lower Vitamin D Status in Patients with Differentiated Thyroid Carcinoma
Authors: Cocolos Andra , Ghemigian Adina , Dumitru Nicoleta , Petrova Eugeniya Nedeltcheva , Ghemigian Mircea , Caragheorgheopol Andra , Ioachim Dumitru , Poiana Catalina
Published: February 2020

Thyroid cancer (TC) has become the most rapidly increasing type of cancer representing 1-1.5% of all cancers diagnosed annually probably due to intensive screening. It is estimated that the death rate of TC has slowly increased from 0.49 to 0.51/100.000 in the last 10 years and 53.990 new cases will be diagnosed in 2018 in the United States. Therefore, efforts are being made in order to stop the increasing incidence and genetic alterations are thoroughly studied. One of the most recent incriminated factors in TC etiology and physiopathology is vitamin D deficiency. Besides the well-known role in bone metabolism, vitamin D has extra-skeletal effects exerted through the vitamin D receptor (VDR) and has been shown to interfere with many cellular functions such as inhibiting cell proliferation, stimulating differentiation and malignant cell apoptosis in different types of cancer. Cross-sectional, retrospective study which included 114 patients (71 with confirmed thyroid cancer and 43 patients in the control group with benign pathology). Preoperative levels of 25(OH)vitamin D, PTH, biochemical and thyroid panel were measured. The histopathologic features were analyzed. Mean values of vitamin D was 16.31 � 7.14 ng/mL with lower levels in patients with thyroid cancer (14.95 � 5.91 ng/mL) in comparison to patients with benign thyroid pathology (18.55 � 8.41 ng/mL), with a p value of 0.008. Majority of the cases were papillary thyroid cancer (97.18%) in stage 3 (45.07%). Vitamin D levels also correlated negatively with TNM staging. The necessity of further studies is a reality in order to establish if vitamin D deficiency is a possible risk factor for thyroid cancer and its correction can be considered an additional therapy.
A New Robust Top-Down Method for Measurement Uncertainty Estimation of the ED(P)- XRFS Outcomes Carried on a Fluorescence Glass
Authors: Pencea Ion , Branzei Mihai , Cojocaru Mihai Ovidiu , Turcu Ramona Nicoleta , Predescu Cristian , Berbecaru Andrei , Arges Alina Popescu , Comanescu Brindus
Published: February 2020

The rare earths doped glasses have been considered as the best solution to fulfil the increasing demand for cheaper fluorescent taggants. The ensuring a high quality of a spectral taggant batch imposes, among others, an exact chemical composition measurement. The most convenient method for elemental analysis of powdered specimens is Energy Dispersive (Polarised)- X-ray Fluorescence Spectroscopy (ED(P)-XRFS) because it has many advantages: non-destructive, large analytical range, robustness, easy sample preparation, cheaper consumables, less time consuming etc. ED(P)-XRFS has some inherent analytical drawbacks such as: interelements interferences, matrix dependence etc. The only way to overcome the drawbacks is a proper method for the measurement uncertainty (MU) estimation of the outcomes. Consequently, the paper argues that the bottom-up method for MU estimation is feeble as long as the sensitivity coefficients of the factors of uncertainty budget are not well known and documented, which is the habitual case of the ED and WD XRFS bottom-up published methods. The paper substantiates a new robust top-down method for MU estimation of the ED(P)-XRFS outcomes carried on a fluorescence glass. Also, the paper presents a representative case study of appliance of the developed top-down method. The other novelties addressed in the paper are: i. Introducing the robust statistics as further checks for the accuracy of mean and of standard deviation, according to ISO 13583:2015; ii. A new criterion for testing the normal distribution of the mean of a set of fewer outcomes based on Central Limit Theorem and on the central momentum of third orde; iii. The method was implemented for multiple simultaneous outcomes. The top-down method, given in the paper, can be applied to ED- and WD-XRFS routine measurements in industrial laboratories or in material science ones, but it can be adapted, without much effort, to other types of tests e.g. hardness, XRD etc.
The Role of Magnetic Resonance Imaging for Diagnosing Soft Tissue Lesions Associated with Anterior Cruciate Ligament Injuries
Authors: Sendrea Bogdan , Edu Antoine , Viscopoleanu George
Published: February 2020

Magnetic resonance imaging has become the gold standard for soft tissue lesions evaluation especially after a traumatic event where there is need for diagnostic confirmation. The objective of the current paper was to evaluate the ability of magnetic resonance imaging in diagnosing soft tissue lesions in patients who underwent anterior cruciate ligament reconstruction compared with arthroscopic findings. Through the ability to diagnose soft tissue injuries, particularly meniscal lesions, magnetic resonance imaging should be considered as fundamental in guiding therapeutic management in patients with anterior cruciate ligament lesions.
Characterization of the Serum a1-Antitripsine Level in Primary Spontaneous Pneumotorax Patients
Authors: Grigorescu Cristina , Gavril Liviu Ciprian , Gavril Laura , Lunguleac Tiberiu , Ciuntu Bogdan Mihnea , Patrascu Alexandru , Salahoru Paul
Published: February 2020

Diagnosis of primary or idiopathic spontaneous pneumothorax is one of exclusion, and in fact defines an entity that may have a difficult or impossible cause to be highlighted by current means, we consider it appropriate to study these etiopathogenic aspects. There is a definite association between alpha-1 antitrypsin deficiency and pulmonary emphysema and indirect spontaneous pneumothorax secondary to an emphysematous pulmonary lesion. Dose of alpha-1 antitrypsin is an immunoturbinimetric method for in vitro determination of alpha-1 antitrypsin in human serum and plasma. This product is calibrated to be used for the Daytona RX analyzer. The serum level of alpha-1-antitrypsin is not a determining factor in the postoperative evolution characterized by the interval until air loss disappears, but certainly exerts some influence, the exact level of which remains to be determined.
Novel Approach for Optimizing Information Propagation in Dynamic Social Network
Authors: Selva Kumar S. , Kayavizhy N.
Published: February 2020

Identification of potential node is one of the essential operations to be carried out in social network analysis as it is necessary to undertake various important decisions associated with the information propagation. Review of existing literature towards social network highlights that there is very less work carried out towards emphasizing potential node. Therefore, the proposed study offers a novel and unique solution that is capable of optimizing the level of information propagation when it is exposed to dynamic networks. The proposed study has been modeled using graph theory and it uses degree centrality distribution in order to offer more insight towards analyzing the selection of potential nodes in a social network. The study significantly contributes towards precise information propagation and its sustainability in the presence of dynamic social network in every aspect.
НАШ ВНЕСОК У ТРАНСФОРМАЦІЙНІ ПРОЦЕСИ: ЯКИМ ВІН Є І ЩО ПОТРІБНО ДЛЯ ЙОГО ЗБІЛЬШЕННЯ
Authors: Slyusarevskyy Mykola
Published: February 2020

Схарактеризовано основні напрями супроводу українськими соціальними психологами трансформаційних процесів у суспільстві та освіті: 1) відстеження тенденцій динаміки суспільної свідомості за допомогою всеукраїнських репрезентативних опитувань; 2) розроблення практично зорієнтованих теорій, моделей і концепцій, що складають теоретико-методологічний фундамент як дослідження, так і супроводження суспільних змін; 3) донесення отриманих даних і наукових розробок до споживача, науково-методична допомога органам державної влади. Водночас констатовано, що можливості психологічного супроводу трансформаційних процесів в освіті, а тим паче в суспільстві загалом, наразі обмежені як недостатньою державною підтримкою розвитку психологічної науки, так і відсутністю дієвих механізмів упровадження наявних розробок і рекомендацій. Обґрунтовано необхідність затвердження на урядовому рівні Державної цільової програми розвитку психологічної науки в Україні. Порушено надзвичайно гостру для країни, що фактично перебуває в стані війни, проблему підготовки психологічних кадрів. Для її актуалізації проведено порівняльний аналіз стану підготовки психологів в Україні і США. Зроблено висновок про потребу збільшення обсягів і водночас більш раціональної реалізації державного замовлення на підготовку вітчизняних психологічних кадрів, що передбачає його розміщення у провідних університетах та наукових установах психологічного профілю.
НАУКОВО-ПСИХОЛОГІЧНИЙ СУПРОВІД В ОСВІТІ ДІТЕЙ З ОСОБЛИВИМИ ПОТРЕБАМИ
Authors: Prokhorenko Lesya
Published: February 2020

Автором окреслено важливі питання освіти дітей з особливими освітніми потребами, зокрема зосереджено увагу на технологіях соціального, психологічного та педагогічного супроводів дітей з особливими потребами, в яких першочерговим є виявлення особливостей особистісного розвитку дитини та її соціального становлення в умовах школи.Обґрунтовано, що зміна стереотипів у розумінні проблем навчання і виховання дітей з особливими потребами має базуватися на нових підходах, які концентруються не на порушеннях особистості, а містять у підґрунті особистісну орієнтацію, освітні компетентності, створення належних умов щодо рівних можливостей здобуття освіти для дітей та молоді, варіативність навчання відповідно до здібностей та індивідуальних можливостей таких осіб та ін. З урахуванням основних тенденцій щодо змін у системі освіти дітей з особливими освітніми потребами окреслено напрями діяльності, які потребують підвищеної уваги, провідними з яких є: науково-методичний супровід освіти осіб з особливими потребами та психолого-педагогічний супровід таких осіб у процесі навчання, соціалізації, життєдіяльності.
РОЗВИТОК СВІДОМОСТІ ОСОБИСТОСТІ ЯК СТРАТЕГІЧНА МЕТА СУЧАСНОЇ ОСВІТИ
Authors: Pomytkin Eduard
Published: February 2020

Актуалізується проблема модернізації освіти через перехід від знаннєво-репродуктивної парадигми до нової парадигми розвитку свідомості особистості. У цьому контексті війни, корупція і стан екології в Україні розглядаються як наслідок низького рівня свідомості людини. Прикладом освітніх інновацій, розроблених на вказаних засадах, подається інтегративний курс «Людина. Родина. Світ», Дистанційна школа демократії та громадянського суспільства. Наголошується на нагальній необхідності балансування змісту освіти у відповідності до потреб розвитку особистості.
ПРО ВИКОНАННЯ ВІДДІЛЕННЯМ ЗАГАЛЬНОЇ СЕРЕДНЬОЇ ОСВІТИ ПЛАНУ ЗАХОДІВ НАПН УКРАЇНИ ІЗ ЗАПРОВАДЖЕННЯ КОНЦЕПЦІЇ РЕАЛІЗАЦІЇ ДЕРЖАВНОЇ ПОЛІТИКИ У СФЕРІ ФОРМУВАННЯ ЗАГАЛЬНОЇ СЕРЕДНЬОЇ ОСВІТИ «НОВА УКРАЇНСЬКА ШКОЛА»
Authors: Liashenko Oleksandr
Published: February 2020

Від початку реформування загальної середньої освіти вчені Національної академії педагогічних наук України активно включилися в процеси науково-методичного супроводу трансформації української школи на нових концептуальних засадах за такими напрямами: концептуальне обґрунтування необхідних змін у загальній середній освіті, законодавче і нормативно-правове забезпечення реформування української школи, навчально-методичне забезпечення модернізації змісту загальної середньої освіти, організаційно-методичний супровід реформи школи на компетентнісних засадах. На всіх цих напрямах учені Академії мають вагомі здобутки: у складі робочих груп вони розробляли законодавчу базу реформування освіти, брали участь у створенні Державного стандарту початкової освіти і проєкту стандарту базової середньої освіти, розробили варіант типової освітньої програми для початкової школи, підготували і видали 11 підручників для першого і 13 підручників для другого класу, за якими навчаються понад 50 відсотків учнів. Лише в 2018-2019 рр. за результатами Всеукраїнського конкурсу рукописів підручників підготовлено і видано 5 підручників для 5 класу, 4 − для 6 класу, 20 – для 10 класу, 16 – для 11 класу. Загалом ученими Відділення загальної середньої освіти протягом 2018-2019 рр. опубліковано понад 270 назв наукової, навчальної і методичної продукції, спрямованої на успішну реалізацію концепції Нової української школи, у тому числі 70 підручників і навчальних посібників, 30 методичних посібників, розробок і рекомендацій, понад 170 статей. Більшість із них є у вільному доступі в Електронній бібліотеці НАПН України та активно використовується вчителями та іншими її відвідувачами.
ПРО ДІЯЛЬНІСТЬ ДЗВО «УНІВЕРСИТЕТ МЕНЕДЖМЕНТУ ОСВІТИ» ЩОДО РЕАЛІЗАЦІЇ КОНЦЕПЦІЇ «НОВА УКРАЇНСЬКА ШКОЛА» У СИСТЕМІ ПІСЛЯДИПЛОМНОЇ ОСВІТИ
Authors: Kyrychenko Mykola
Published: February 2020

У доповіді здійснено теоретичний аналіз сучасного стану розвитку післядипломної педагогічної освіти в Україні, виявлено найбільш важливі педагогічні та психологічні проблеми, що детермінують цей процес; окреслено основні тенденції й перспективи модернізації освітньої галузі в контексті реформування вітчизняної освіти. Обґрунтовано соціальне значення післядипломної педагогічної освіти в умовах розбудови Нової української школи, розкрито соціальну місію Університету менеджменту освіти та закладів післядипломної педагогічної освіти як інноваційних центрів підготовки, перепідготовки та підвищення кваліфікації вчителів і керівників Нової української школи. Наголошено на унікальності досвіду професійного розвитку фахівців освітньої галузі, накопиченого педагогічними працівниками закладів післядипломної педагогічної освіти.
Darwin wasps: a new name heralds renewed efforts to unravel the evolutionary history of Ichneumonidae
Authors: Klopfstein Seraina , Santos Bernardo F. , Shaw Mark R. , Alvarado Mabel , Bennett Andrew M.R. , Dal Pos Davide , Giannotta Madalene , Herrera Florez Andres F. , Karlsson Dave , Khalaim Andrey I. , Lima Alessandro R. , Mikó István , Sääksjärvi Ilari E. , Shimizu So , Spasojevic Tamara , Van Noort Simon , Vilhelmsen Lars , Broad Gavin R.
Published: February 2020

The parasitoid wasp family Ichneumonidae is arguably one of the groups for which current knowledge lags most strongly behind their enormous diversity. In a five-day meeting in Basel (Switzerland) in June 2019, 22 researchers from 14 countries met to discuss the most important issues in ichneumonid research, including increasing the speed of species discovery, resolving higher-level relationships, and studying the radiation of these parasitoids onto various host groups through time. All agreed that it is time to advertise ichneumonid research more broadly in the scientific community and thereby attract young talents to this group for which specialists are sorely lacking. In order to popularize the group, we here suggest a new name for the family, “Darwin wasps”, to reflect the pivotal role they played in convincing Charles Darwin that not all of creation could have been created by a benevolent god. We hope that the name catches on, and that Darwin wasps start buzzing more loudly across all disciplines of biology.
Preparation and in situ use of unstable N-alkyl a-diazo-g-butyrolactams in RhII-catalyzed X-H insertion reactions
Authors: Eremeyeva Maria , Zhukovsky Daniil , Dar'in Dmitry , Krasavin Mikhail
Published: February 2020

N-Alkyl a-diazo-g-butyrolactams previously found to be unstable and undergo unproductive dimerization to bis-hydrazones, were successfully converted immediately to various X-H insertion products with alcohols, aromatic amines and thiols via an in situ RhII-catalyzed reaction. With aliphatic amines or unreactive, sterically hindered anilines, the reaction tends to yield enamine adducts.
INDUSTRY 4.0 CONCEPTS WITHIN THE CZECH SME MANUFACTURING SECTOR: AN EMPIRICAL ASSESSMENT OF CRITICAL SUCCESS FACTORS
Authors: Nwaiwu Fortune , Duduci Meri , Chromjakova Felicita , Otekhile Cathy-Austin Funke
Published: February 2020

The paper analysed factors that has the most impact in influencing the achievement of a sustainable process management model in the implementation of Industry 4.0 concepts within the Czech SME manufacturing sector. Several factors were identified and their interactions with digital technologies within the production environments was analysed. These factors, from an organisational perspective were identified as critical to success in the quest to achieve Industry 4.0 compliance and digital transformation of the manufacturing operations of companies. They include: strategy, organisational fit, competitiveness, operations and human resources. A mixed methods approach was adopted for the research. It involved both the qualitative and quantitative methodological approaches. The qualitative aspect involved an extensive systematic review of relevant literature which was useful in developing the conceptual framework and identifying the relevant factors that enable the implementation of an efficient Industry 4.0 process management model in SMEs; the quantitative aspect involved the use of a survey questionnaire to collect data which was analysed using confirmatory factor analysis statistical approach to test the measures of the constructs in the proposed conceptual framework. The result from the statistical analysis shows the factors that in the conceptual model that were supported as being relevant in achieving an efficient process management model for successful implementation of Industry 4.0 concepts in Czech manufacturing SMEs. The research limitation is based on the fact that the SMEs covered in the quantitative aspect of the research are restricted to a particular geographical location – Czech Republic. It would be interesting to have similar studies conducted in other geographies for a comparative perspective. It contributes to the scientific and practical discourse on Industry 4.0 process management model implementation in SMEs by investigating the phenomenon through the production of credible scientific evidence.
AN IMPROVED TIME-COST TRADE-OFF MODEL WITH OPTIMAL LABOR PRODUCTIVITY
Authors: Lin Chien-Liang , Lai Yu-Che
Published: February 2020

Optimization of the time-cost trade off (TCT) has received considerable attention for several decades. However, few studies
have considered improving performance/productivity of existing crews. To shorten the gap to real-world applications, this study presents an improved
TCT model that considers variable productivity using genetic algorithms (GAs). Through an illustrative case and a real world case, the results
demonstrate that improving labor productivity of selected activities by allocating existing crews and management can yield an optimized solution.
As such, a decision maker can implement a better optimized technique to reduce a project duration under budget while reducing the risk of liquidated
damages. The main contribution of this study is to apply managerial improvement of labor productivity to TCT optimization, the project duration can be
reduced owing to improved productivity of existing crews rather than inefficient overmanning, overlapping or costly substitution. In the end, three
important managerial insights are presented and future research is recommended.
Yarkovsky Drift Detections for 247 Near-Earth Asteroids
Authors: Greenberg Adam H. , Margot Jean-Luc , Verma Ashok K. , Taylor Patrick A. , Hodge Susan E.
Published: February 2020

The Yarkovsky effect is a thermal process acting upon the orbits of small celestial bodies, which can cause these orbits to slowly expand or contract with time. The effect is subtle (

au My−1 for a 1 km diameter object) and is thus generally difficult to measure. We analyzed both optical and radar astrometry for 600 Near-Earth Asteroids (NEAs) for the purpose of detecting and quantifying the Yarkovsky effect. We present 247 NEAs with measured drift rates, which is the largest published set of Yarkovsky detections. This large sample size provides an opportunity to examine the Yarkovsky effect in a statistical manner. In particular, we describe two independent population-based tests that verify the measurement of Yarkovsky orbital drift. First, we provide observational confirmation for the Yarkovsky effect’s theoretical size dependence of 1/D, where D is diameter. Second, we find that the observed ratio of negative to positive drift rates in our sample is 2.34, which, accounting for bias and sampling uncertainty, implies an actual ratio of

. This ratio has a vanishingly small probability of occurring due to chance or statistical noise. The observed ratio of retrograde to prograde rotators is two times lower than the ratio expected from numerical predictions from NEA population studies and traditional assumptions about the sense of rotation of NEAs originating from various main belt escape routes. We also examine the efficiency with which solar energy is converted into orbital energy and find a median efficiency in our sample of 12%. We interpret this efficiency in terms of NEA spin and thermal properties.
Thermal Regulation and the Star-forming Main Sequence
Authors: Steinhardt Charles L. , Jermyn Adam S. , Lodman Jackie
Published: February 2020

We argue that the interplay between cosmic rays, the initial mass function (IMF), and star formation plays a crucial role in regulating the star-forming “main sequence.” To explore these phenomena we develop a toy model for galaxy evolution in which star formation is regulated by a combination of a temperature-dependent IMF and heating due to starlight, cosmic rays, and (at very high redshift) the cosmic microwave background. This produces an attractor, near-equilibrium solution which is consistent with observations of the star-forming main sequence over a broad redshift range. Additional solutions to the same equations may correspond to other observed phases of galaxy evolution, including quiescent galaxies. This model makes several falsifiable predictions, including higher metallicities and dust masses than anticipated at high redshift and isotopic abundances in the Milky Way. It also predicts that stellar mass-to-light ratios are lower than produced using a Milky Way–derived IMF, such that inferences of stellar masses and star formation rates for high redshift galaxies are overestimated. In some cases, this may also transform inferred dark matter profiles from core-like to cusp-like.
Communicative and educational strategies to improve adolescents’ health
Authors: Guadarrama-Rico Luis-Alfonso , Valero-Vilchis Jannet
Published: February 2020

One of the challenges of the present century is to achieve adolescents and young adults’ complete development taking as a basis healthy behaviours and a culture of selfcare. On this basis in Toluca, a town in the State of Mexico, an interdisciplinary group has started an action programme dedicated to produce communicative and educational strategies to improve face-to-face and media interactions in order to promote a healthy behaviour in this group of population.

Uno de los retos del presente siglo es lograr que la población adolescente y juvenil se desarrolle plenamente, teniendo como base comportamientos saludables y una cultura del autocuidado. Sobre esta base, en el municipio de Toluca (Estado de México), un grupo interdisciplinario ha puesto en marcha un programa de acción dedicado a operar estrategias comunicacionales y educativas para mejorar las interacciones cara a cara y mediáticas, a fin de promover comportamientos saludables en este grupo de población.
Media Education as a basis for civic education
Authors: Tucho-Fernández Fernando
Published: February 2020

Civic education emerges as a new subject in the Spanish school after the last reform of the currículo. What kind of citizens and what kind of education are we talking about when we promote civic education? This paper reflects upon these topics and asks for the role of media education in the upbringsing of a critical, active, creative citizenship. A case of study joining media education and civic education is the «Student Voices project» developed in some American schools.

La educación para la ciudadanía ha surgido como una nueva materia obligatoria en las enseñanzas no universitarias españolas tras la última reforma educativa. De cara a definir esta nueva asignatura es clave plantearnos de qué tipo de ciudadanía estamos hablando y qué tipo de educación es necesaria para su consecución. En este artículo planteamos el debate sobre estas cuestiones y reclamamos el papel que la educación en comunicación debe desempeñar en la formación de una ciudadanía crítica, activa y creativa. Como propuesta conjunta de vinculación de ambas materias se presenta el caso concreto del «Student Voices Project» desarrollado en escuelas estadounidenses.
Interactive digital TV and its learning tools
Authors: González-Gómez Antonia-Alejandra , Jiménez-Comrie Karla
Published: February 2020

Interactive Digital TV (IDTV) is a reality in the midst of the Information Society, is expected to allow the development of new interactive systems that may be useful in daily life as well as in other scopes such as education, politics and economics. The implications that IDTV requires to mature settles new challenges for both public and private authorities, and, demands also, new standards for other aspects such as technolgy applications, television industry, legal frames, social envioroments and education fields. This paper presents the basis of IDTV and also looks beyond to explore what are the outlines that can be used to provide an efficient broadcast and interactivity.

La televisión digital interactiva es una realidad de la llamada «sociedad de la información» que funciona a partir de la difusión de la televisión directa, de las redes por cable y de la televisión digital terrestre, junto con la mejora de la calidad en la recepción y visualización de las señales televisivas, de los sistemas digitales de interacción y de la recepción portátil y móvil de la señal de televisión. En ese sentido, en el futuro se espera que las computadoras unidas con las emisiones televisivas digitales, permitan el desarrollo de sistemas interactivos que se puedan aplicar tanto en la vida cotidiana como en la educación formal y no formal. Las implicaciones que la televisión digital interactiva conlleva, provocan una reconversión en la tarea de los medios de comunicación y plantean nuevos retos en los poderes públicos y privados. En el campo educativo, la televisión digital interactiva representa oportunidades de interacción viva con el usuario, sin embargo en el momento actual, las investigaciones en este campo son escasas.
Discourse and socialization in children´s cinematographic productions
Authors: Martínez Alejandra , Merlino Aldo
Published: February 2020

Understanding that cultural products for children transmit social representations and reproduce specific outlines of attitudes and behaviours, this paper focuses on the gender construction based on specific messages in children´s films. We analyze here, the 1991 Disney´s Company cartoon film «The Beauty and the best».

Entendiendo que los productos culturales dirigidos a los niños son transmisores de representaciones sociales y reproducen esquemas específicos de actitudes y comportamientos, este artículo aborda la temática de la construcción de los géneros a partir de mensajes específicos en producciones cinematográficas infantiles. Se analiza aquí, en torno al tema planteado, el film animado de 1991 de la compañía Disney «La bella y la bestia»
Mass media, non-formal education and social representations on violence
Authors: Liceras-Ruiz Ángel
Published: February 2020

Mass media, through their programs, news and the informal education they spread, show social representation on reality, being the ones referring to violence of great importance in our culture. In order to investigate on the educative influence of mass media in the social representations on violence and the social practices that such representations favour, its characteristics and their school discussion make specific the content of this paper.

Los medios de comunicación de masas, a través de sus programas e informaciones y de la educación informal que difunden, contribuyen a conformar representaciones sociales sobre la realidad que muestran. Entre ellas, las referidas al fenómeno de la violencia constituyen hoy día un componente de enorme importancia en nuestra cultura social. Indagar sobre la influencia educativa que ejercen los medios de comunicación en la configuración de representaciones sociales sobre la violencia y las prácticas sociales que tales representaciones favorecen, sus características y su tratamiento escolar concreta el contenido de este artículo.
L’accessibilité des manuels scolaires numériques : l’exemple suédois, entre édition adaptée et édition inclusive
Authors: Castillan Laetitia , Lemarié Julie , Mojahid Mustapha
Published: February 2020

Depuis le plan Handiscol (1999) et plus récemment avec la loi du 11 février 2005, les politiques promeuvent l’inclusion des élèves en situation de handicap. Si pour l’heure, les élèves déficients visuels inclus en établissement ordinaire disposent des contenus pédagogiques adaptés par des services dédiés, l’arrivée sur le marché des manuels scolaires numériques, impulsée par le Plan numérique pour l’éducation, pourrait modifier les pratiques d’adaptation, mais aussi les situations d’apprentissage. En effet, la volonté de passer d’une édition adaptée à une édition inclusive semble actuellement au cœur des préoccupations. Cependant, si l’édition inclusive est d’ores et déjà atteignable pour les ouvrages littéraires, l’accessibilité native des contenus pédagogiques reste encore problématique. À travers l’exemple de la Suède, qui a fait le choix d’une adaptation numérique des manuels scolaires, les limites et bénéfices de l’usage de manuels scolaires numériques par des élèves déficients visuels en inclusion seront présentés et discutés ainsi que les impacts que ces changements pourraient introduire dans le processus d’adaptation des contenus pédagogiques en France.
Mieux comprendre les peurs féminines : la socialisation sexuée des enfants aux espaces publics urbains
Authors: Rivière Clément
Published: February 2020

Résumé Si l’accès plus difficile des femmes aux espaces publics urbains a été mis en lumière de longue date par la recherche en sciences sociales, la connaissance des processus socialisateurs qui sous-tendent cette différenciation sexuée demeure lacunaire. S’appuyant sur une enquête par entretiens menée auprès de 88 parents de 123 enfants âgés de 8 à 14 ans (69 garçons et 54 filles) à Paris (France) et Milan (Italie), cet article décrit la façon dont les parents encadrent de manière différenciée les usages que les enfants font de ces espaces selon le sexe biologique de ces derniers. Cette approche de l’action socialisatrice des parents apporte un éclairage empirique sur la sociogenèse des manières d’agir des femmes adultes dans les espaces publics urbains, l’encadrement parental contribuant à la formation de dispositions sexuées.
Être solidaire. De qui, pour quoi ?
Authors: Blais Marie-Claude
Published: February 2020

Cet article retrace le processus qui a permis à l’idée de « solidarité », née dans les milieux progressistes de la Restauration, de passer du champ des sciences naturelles et sociales vers la sphère politique. Ce transfert est l’œuvre d’un premier ministre radical de la III e  République, Léon Bourgeois, qui, en 1896, formula une doctrine politique reposant sur les obligations générées par le fait irrécusable de l’interdépendance entre tous les hommes. Sous le nom de « solidarisme », il inventa ainsi un modèle à la fois social et libéral susceptible de s’opposer au libéralisme sans frein comme aux idées collectivistes montantes. C’est cette synthèse démocratico-libérale qui se cherche encore aujourd’hui à travers les politiques publiques de solidarité, au niveau national comme international.