bluuebunny/crossref_metadata_2025 huggingface dataset:
MIND AND KIDNEY REPORT OF THE LAUREAT OF THE BIG GOLD MEDAL NAMED AFTER M.V. LOMONOSOV RAS 2022
Authors: Natochin Yu. V.
Published: April 2024

The report, presented at the General Meeting of the Members of the Russian Academy of Sciences on May24, 2023, was devoted to the results of the author’s research on the physiology of the kidney and water-salt balance, and the practical significance of the results obtained. The author noted that the kidneys provide conditions for the stability of the volume of each cell of the body, maintaining the constancy of blood osmolality, blood volume in the vessels and the total volume of extracellular fluid in the body, constancy of blood pressure, the desired level of blood clotting; the kidneys are involved in regulating the balance of inorganic ions, digesting proteins, hydrolyzing altered proteins in the blood serum, in the synthesis of glucose in its deficiency, maintaining a constant concentration of many organic substances in the blood serum, hormone secretion, and many other processes.
Yu.V. Natochin defends the point of view, according to which the kidney is both an organ for excreting unnecessary substances from the blood and storing the necessary substances in it; it is the kidney that allows you to create an ideal composition of the environment surrounding every cell of the body. Another important postulate concerns the origin of life on Earth. The author disputes the widespread hypothesis about the origin of life in the sea water environment, since, in order to ensure the synthesis of polypeptides, the concentration of inorganic substances, in particular potassium ions, must be equal inside and outside the cell in the first emerging cell.
BACTERIAL PALEONTOLOGY TODAY AND TOMORROW
Authors: Rozanov A. Yu.
Published: April 2024

The history of bacterial paleontology is outlined. The author describes how the refinement of methods has lead to confirmation or rejection of proposed hypotheses. The role of ancient bacteria in the genesis of sedimentary rocks and the importance of bacterial paleontology for understanding the origin and evolution of weathering rinds and paleosols are emphasized. Incorporating this discipline into university curricula is important to attract young researchers to this field of study.
SCIENCE AND SOCIETY LEGAL STRATEGY OF SCIENTIFIC AND TECHNOLOGICAL DEVELOPMENT OF RUSSIAN FEDERATION
Authors: Kabyshev S. V.
Published: April 2024

Science must serve society, and it is through law that the attitude of the state to scientific activity is formulated, its social goal-setting is expressed, and the interests and requirements associated with obtaining a socially significant scientific effect are fixed. In modern realities, accelerated scientific and technological progress is becoming a historical imperative for the successful development of Russian statehood, and domestic jurisprudence must offer an effective legal strategy for scientific and technological development. Based on constitutional principles, the article discusses some of the main aspects of this strategy regarding its categorical apparatus, value-ideological and structural-economic orientation, organizational-administrative and spatial-territorial components. Proposals and approaches aimed at improving the legislative basis of the state scientific and technical policy are formulated.
PIONEER OF INFORMATION SCIENCE AND CYBERNETICS ON THE 100TH ANNIVERSARY OF THE BIRTH OF ACADEMICIAN V.M. GLUSHKOV
Authors: Kitov V. A.
Published: April 2024

The article is devoted to the life and work of the outstanding Soviet scientist, pioneer of informatics and cybernetics, initiator of the development of a nationwide automated management information system, Academician of the Academy of Sciences of the USSR Viktor Mikhailovich Glushkov (1923–1982). The author tells about the main stages of his biography, focusing on the scientific achievements: the solution of the fifth generalized Hilbert problem, the creation of the USSR’s largest Institute of Cybernetics of the Academy of Sciences of the Ukrainian SSR, the development of the theory of digital automata, the first personal computers for engineering calculations, the most powerful supercomputers in the USSR with a new macro-pipeline architecture, contribution to cybernetics and computer science, programming theory and systems of algorithmic algebras, to the creation of artificial intelligence systems. Attention is paid to the role of V.M. Glushkov as an ideologist and one of the creators of the industry of management information systems in the USSR, scientific director of large industrial management information systems. Particular attention is paid to the National Automated System for the Collection and Processing of Information proposed by him for accounting, planning and management of the national economy.
PROCESSES OF GLOBALIZATION AND DEGLOBALIZATION IN CONDITIONS OF GROWING CONFRONTATION BETWEEN THE USA AND CHINA AND RUSSIA’S INTERESTS
Authors: Kokoshin A. A. , Kokoshina Z. A.
Published: April 2024

According to the authors of the article, issues of globalization and deglobalization need to be considered primarily through the prism of the growing confrontation between the two largest states in the world – USA and China. The scale and depth of this confrontation is growing; it is becoming more and more ideological, as well as political-military in character. United States due to a complex set of internal problems are now the main driving force behind deglobalization, although 25–30 years ago it was this country that was at the forefront of the reverse process – globalization. On the contrary, the leadership of the PRC, which has received great benefits from participation in the economic globalization, including within the framework of the World Trade Organization, persistently demonstrates its commitment to the growing economic interdependence of countries and regions. This commitment is noted, among other things, in Russian–Chinese documents of the highest level. The processes of globalization and deglobalization are of great importance for the socio-economic development of Russia, whose economy is part of the world economy, despite all the antirussian efforts of the collective West as part of its hybrid war against the Russian Federation.
THE FUNDAMENTAL CONTRIBUTION OF THE ACADEMY OF SCIENCES TO THE DEVELOPMENT OF RUSSIAN COMPUTER SCIENCE AND COMPUTER TECHNOLOGY
Authors: Prokhorov S. P.
Published: April 2024

The history of the creation of the first Soviet universal electronic computers is an excellent example of the ability and readiness of the Academy of Sciences to be a leader in the creation and development of new areas of science and technology. All work, starting with the design of computers and ending with the stage of creating computers and software, was carried out at the institutes of the Academy of Sciences. On December 4, 1948, I.S. Brook and B.I. Rameev received a copyright certificate for the invention of an automatic digital machine. It was the first official document indicating the beginning of work on the creation of computers in the USSR. The first Soviet computer, the M-1, was created at the Power Energy Institute under the leadership of Corresponding Member I.S. Brook. At the Institute of Precise Mechanics and Computer Engineering, under the guidance of Academician S.A. Lebedev, the most successful series of Soviet computers, BESM, was produced. The first copies of all new models of computers before being launched into a series were subjected to comprehensive tests at the Institute of Applied Mathematics, whose director was Academician M.V. Keldysh. Academician S.L. Sobolev was the ancestor of the Russian school of programming. The article contains little-known information about the first steps of computer science in Russia. Some facts about the history of those years were hidden in the archives for a long time and are now published for the first time.
“CHEMISTRY IS THE MOST INTERESTING SCIENCE” ON THE 120TH ANNIVERSARY OF THE BIRTH OF ACADEMICIAN B.A. ARBUZOV
Authors: Koreeva N. S.
Published: April 2024

The article is devoted to the life and work of Academician Boris Alexandrovich Arbuzov (1903–1991). He entered the history of Russian science not only as an outstanding scientist, teacher, public figure, but also as a continuer of the traditions of the Kazan Chemical School, who gave her more than 60 years of life. B.A. Arbuzov is the author of classical works in the field of organic chemistry, heterocycle chemistry, organophosphorus compounds, natural compounds – terpenes, as well as polymer chemistry. A special aspect of his scientific work is the application of physical and physico-chemical methods in chemical research. In our country, Watermelon is rightfully considered the founder of the research of fine details of the spatial structure (conformational analysis) of organic and organoelement compounds.
RETURN OF DEVELOPMENT: A POLYCENTRIC WORLD IN SEARCH OF A NEW EXISTENTIAL PARADIGM
Authors: Volodin A. G.
Published: April 2024

The article examines the evolution of the theories of socio-economic modernization at the end of the XX – first quarter of the XXI century. In the last century, creative rivalry took place between three main ideological and theoretical trends – West-centrist, national-statist and left-wing radical. The difficulties of transforming the complex socio-economic structure of transitional societies have predetermined the gradual loss of the influence of the West-centrist trend and the increasing importance of national-statist and left-wing radical сurrents of thought in the system of knowledge about developing countries. The “truncated globalization” and the “Washington consensus” resulted in the collapse of the monocentric world order and put the development paradigm at the center of the search for a new model of human evolution. Today, development is objectively becoming an imperative for the modernization of all societies, including those of the industrialized nations. The “Development agenda” is, therefore, emerging as an important precondition for the formation of a new, polycentric model of international relations, which is based on the principles of dialogue and interaction between States and civilizations.
PROBLEMS OF THE RECLAMATION AND WATER MANAGEMENT COMPLEX THE LOWER DON IN THE CURRENT CLIMATIC CONDITIONS
Authors: Shevchenko V. A. , Isaeva S. D. , Dedova E. B.
Published: April 2024

Long-term climatic changes have led to a decrease in the water content of a number of Russian rivers. In the pool of R. The Don phase of low water content has been going on since 2007. In addition, due to climate warming, significant fluctuations in the intra-annual hydrological regime are observed. The climatic situation and high anthropogenic pressure on water resources complicate the conditions for the development of irrigated agriculture. At the same time, there is an obvious need to increase the area of irrigated land on the Lower Don. The authors of the article propose a number of measures that contribute to the effective development of the Nizhny Don water management complex against the background of water scarcity. The possibility of replenishing the flow of the Don River is considered. In the conditions of the Azov-Don basin, a geoinformation web-based decision support system for integrated management of the reclamation and water management complex developed at the Federal Scientific Center for Hydraulic Engineering and Melioration named after A.N. Kostyakov can be used. The proposed hydrodynamic model of the Lower Don can be used in order to form optimal modes of operation of the Tsimlyansk hydroelectric complex in the interests of agricultural and fisheries water users.
R.V. Kuznetsova, V.N. Kuznetsov, O.Yu. Zharkov, N.A. Antipin. Igor Kurchatov: the Ural trace in science. Yekaterinburg: Bank of Cultural Information, 2023. 560 p. (the series “The National Treasure of Russia. Outstanding scientists of the Urals”)
Authors: Tolstikov V. S. , Zapariy V. V.
Published: April 2024

The book by R.V. Kuznetsova, V.N. Kuznetsov, O.Yu. Zharkov, and N.A. Antipin Igor Kurchatov: Ural Trace in Science is reviewed.
Homology Violation in a Series of Amphiphilic Comb-Like Statistical Copolymers of N-Methyl-N-vinylacetamide and N-Methyl-N-vinylamine with Moderate Density of Grafting of Side Dodecyl Groups
Authors: Gosteva A. A. , Okatova O. V. , Gavrilova I. I. , Panarin E. F. , Pavlov G. M.
Published: April 2024

A series of water-soluble comb-like copolymers of N-methyl-N-vinylacetamide and N-methyl-N-vinylamine (MVAA‒со‒MVA) bearing hydrophobic dodecyl side groups С12Н25 has been investigated by means of molecular hydrodynamics (viscometry, translational diffusion, and analytical ultracentrifugation) in dilute solutions in 0.1 M NaCl, under conditions of suppression of the polyelectrolyte effects. The issues of homology of these amphiphilic copolymers have been considered. The viscometry data plotted as lnηr as function of c[η] have allowed to distinguish between macromolecules of the copolymers according to their hydrophobicity. Positive values of the second derivative B2 determined from the initial parts of these curves have served as a measure of hydrophobicity of the amphiphilic copolymers. The noticeable differences in the B2 values for different copolymers have shown that they do not form true homologous series. For the quasi-homologous series of the MVAA–со–MVAC12H25·HI copolymers with close values of B2, the Kuhn–Mark–Houwink–Sakurada relationships have been obtained and the equilibrium rigidity of the chains has been assessed using the modified Gray–Bloomfield–Hearst equation.
Structural–Morphological and Rheological Features of Joint Solutions of Cellulose and PAN Copolymer in N-Methylmorpholine-N-Oxide
Authors: Vinogradov M. I. , Makarov I. S. , Golova L. K. , Bondarenko G. N. , Kulichikhin V. G.
Published: April 2024

Mixed 18% solutions of cellulose and PAN terpolymer containing methyl acrylate and methylsulfonate comonomers in N-methylmorpholine-N-oxide have been obtained over the entire range of compositions. All the obtained systems based on cellulose and PAN are biphasic, and the morphological features of the emulsions change from highly dispersed isotropic to fibrillar depending on the phase composition and the intensity of the deformation effect. At high shear stresses that emerge during preparation of the solutions in an extruder, all emulsions are characterized by the same microheterogeneous morphology, which is transformed into fibrillar by deformation. An IR spectroscopic study has established that in the preparation process, specific interactions occur between the functional groups of macromolecules of the cocomponents, leading to the formation of PAN/cellulose associates, which undergo hydrophobic repulsion along the interfaces. It is this process that initiates the fibrillation of the cellulose solution phase in the presence of a PAN solution during deformation. The rheological behavior of mixed solutions over the entire range of concentrations in continuous and dynamic modes at temperatures of 110–130°C is a direct consequence of the phase composition and morphological transformations occurring during deformation. Emulsion compositions characterized by viscoelastic properties that make it possible to successfully form composite fibers have been chosen.
Polymer Electrolytes Based on Polybenzimidazole, Poly(Vinylidene Fluoride-co-Hexafluoropropylene), and Ionic Liquids
Authors: Safonova L. P. , Shmukler L. E.
Published: April 2024

Ionic liquids, salts with melting temperature below 100°C, have continuously attracted research interest. Introduction of ionic liquids in a polymer matrix affords polymer electrolytes exhibiting extremely high electroconductivity and electrochemical stability, membranes on their basis possessing good mechanical properties. Diversity of the polymers/copolymers suitable as the matrix as well as practically unlimited variety of ionic liquids (obtained via variation of the anion-cation composition and additional modification of the ions chemical structure) have afforded the polymer electrolytes with a wide range of the physico-chemical properties. In this study, the attention has been primarily focused on the results published over the recent decades and related to investigation of electrolytes for electrochemical devices, in which the membranes based on polybenzimidazole (meta-PBI), the poly(vinylidene fluoride-со-hexafluoropropylene) (PVdF-HFP) copolymer, and ammonium or imidazolium ionic liquids have been used. Various types of polymer electrolytes differing in the composition and the application range have been considered in this study: polymer + ionic liquid, polymer + ionic liquid + acid, and polymer + ionic liquid + lithium/sodium salt. Moreover, the influence of the fillers, introduced in the above-said polymer electrolytes to improve the properties and resolve the issue of the ionic liquid retention in the membrane, has been discussed. This report presents vast data sets (tables) on the electroconductivity and thermal stability of more than 100 polymer electrolytes, which are demanded by the broad journal audience.
Rasio Efektivitas Dan Kontribusi Pajak Daerah Terhadap Pendapatan Asli Daerah
Authors: Widodo Wahyu , Widodo Nova Maulud , Prihadyatama Ardila
Published: April 2024

The Covid-19 pandemic in 2018 – 2022 will cause a decrease and increase in regional tax revenues, resulting in potential fluctuations in the level of effectiveness and tax contribution of a region. This research aims to determine the level of effectiveness and contribution of taxes in conditions before the pandemic, during the pandemic and after the pandemic. This research uses original regional income data and the realization of Madiun City regional taxes obtained directly from the Madiun City Revenue Agency. The data collection method is secondary data observation, using quantitative data so that researchers can make an analysis of the effectiveness and contribution of local taxes to Madiun City's local revenue. According to the research results, it can be seen that the effectiveness level of Madiun City is in the very effective category because the average value of effectiveness exceeds 100%, namely 111.67%. Madiun City's regional tax contribution is in the quite good category because it only gets an average value of 36.54% and this means that the majority of Madiun City's original regional income does not come from regional taxes but from other legitimate income such as asset sales and investments
Pengaruh Motivasi Dan Semangat Kerja Karyawan Dalam Upaya Meningkatkan Produktivitas Pada PT. X Jakarta
Authors: Aini Marina , Sari Imelda , Astuti Dewi
Published: April 2024

PT. X is an official distributor company which operates in the field of providing laptop products and providing various kinds of computer hardware and software. The increasing mobility of people and the importance of devices to support their productivity has made the company want to increase PT. X's sales turnover, which is one of the company's goals. However, efforts to increase sales turnover can cause higher levels of employee pressure and decreased work morale. The increasing level of employee pressure and decreasing work morale at PT. X could be a negative impact of the company's efforts to increase sales turnover. Increased stress and decreased morale can become a dangerous cycle for a company. Increasing employee motivation and morale is an important responsibility for the leadership of an organization. A visionary leader needs to create a conducive organizational climate to maintain the morale and work dedication of his team members. The main goal of effective leadership is to inspire and motivate employees. This research uses quantitative methods, the samples in this research are all employees in the IT and Service division of PT. X, totaling 30 people. The research results show that based on the presentation of the results that have been presented, it can be seen that the Fcount value is more than Ftable (3.354) with a significance level of <0.05, so it can be concluded that the motivation and work enthusiasm variables together have an effect on productivity (Fcount 14.101 > Ftable 3.354). Bearti H3 is accepted, motivation and work enthusiasm have a simultaneously positive and significant influence on productivity.
Determination of Mahkota Gold Pringsewu Customer Satisfaction
Authors: Wulandari Adellia , Warganegara Tri Lestira Putri
Published: April 2024

Because of their abundance, Pringsewu's gold stores face fierce competition. Service quality, product quality, product design, and gold cleaning quality are what distinguish one business from the others and help it maintain customer loyalty. The goal of this study is to discover and explain how marketing messages and product quality influence customer satisfaction. This research takes a quantitative approach. There were 110 participants in this research overall. Using the Simple Random Sampling approach, 86 respondents were selected from the Mahkota Gold  Pringsewu customer base for this study. This study relied on primary data. The data for this study was gathered using a Likert scale questionnaire technique. According to the findings of the study on Determining Customer Satisfaction at Mahkota Gold Pringsewu, there is a positive and significant relationship between product quality and customer satisfaction; there is also a positive and significant relationship between product quality and marketing communication, and there is a positive and significant relationship between the two for Mahkota Gold  Pringsewu customers. This implies that high-quality products and marketing messages have a big influence on consumer happiness.
A Comparative Evaluation of Error Processing Performance and its Relationship with Cognitive Function in Patients with Alzheimer’s Disease, Individuals with Mild Cognitive Impairment, and Normal Controls Using the Event-Related Potentials
Authors: Hedayatjoo Mohammad , Tehrani-Doost Mehdi , Vahabi Zahra , Akbarfahimi Malahat , Khosrowabadi Reza
Published: April 2024

Background:

Some pathological changes occur in patients with Alzheimer’s disease (AD) prior to the onset of clinical symptoms.

Objective:

In the present study, we aimed to investigate the potential of event-related potential (ERP) components in error processing performance as a neuromarker of mild cognitive impairment (MCI) and transition to AD and their relation with cognitive functions.

Methods:

We conducted an evaluation of 16 patients diagnosed with AD, 16 patients with MCI, and 15 normal controls using three subtests from the Cambridge Neuropsychological Testing Automated Battery (CANTAB). The ERP components of error processing were extracted and compared among the three groups using a modified version of the Eriksen flanker task. Additionally, we assessed the correlation between the cognitive results and the ERP components.

Results:

Significant differences were observed among the three groups in terms of providing correct responses following errors and the amplitude of error-related negativity (ERN). These differences were also significant between all paired groups. Regarding other ERP components of error processing and the peak latency of ERN, no significant differences were observed among the three groups. The findings revealed that the spatial working memory and new learning were correlated with the amplitude of ERN.

Conclusions:

In the context of error processing performance, both the accuracy of responses following an error and the amplitude of ERN can be considered as indicators of MCI and its progression to AD. The present findings do not support the use of other error processing components as differential markers in the three groups.
Cognitive Impairment in the Post-Acute Phases of COVID-19 and Mechanisms: An Introduction and Narrative Review
Authors: Wang Weiye , Cui Ruxin , Leng Luming , Wang Gang , Peng Guoping
Published: April 2024

Cognitive impairment is a primary manifestation of neurological symptoms associated with COVID-19 and may occur after disease resolution. Although cognitive impairment has been extensively reported in the literature, its duration and rate of remission remain controversial. This study discusses the various factors that influence cognitive impairment, including demographic characteristics, genetics, as well as disease course and severity. Furthermore, imaging and laboratory data have suggested various associations with cognitive impairment, most notably changes in EEG patterns, PET imaging, and serum markers. Some findings suggest similarities and potential links between COVID-related cognitive impairment and Alzheimer’s disease. Moreover, this study reviews the various mechanisms proposed to explain the development of cognitive impairment in COVID-19, including cytokine storm, damage to the blood-brain barrier, compromise of small vessel integrity, hypoxic conditions, and immune dysregulation.
Predictive Modeling Using a Composite Index of Sleep and Cognition in the Alzheimer’s Continuum: A Decade-Long Historical Cohort Study
Authors: Yu Xianfeng , Deng Shuqing , Liu Junxin , Zhang Mingkai , Zhang Liang , Li Ruixian , Zhang Wei , Han Ying
Published: April 2024

Background:

Sleep disturbances frequently affect Alzheimer’s disease (AD), with up to 65% patients reporting sleep-related issues that may manifest up to a decade before AD symptoms.

Objective:

To construct a nomogram that synthesizes sleep quality and cognitive performance for predicting cognitive impairment (CI) conversion outcomes.

Methods:

Using scores from three well-established sleep assessment tools, Pittsburg Sleep Quality Index, REM Sleep Behavior Disorder Screening Questionnaire, and Epworth Sleepiness Scale, we created the Sleep Composite Index (SCI), providing a comprehensive snapshot of an individual’s sleep status. Initially, a CI conversion prediction model was formed via COX regression, fine-tuned by bidirectional elimination. Subsequently, an optimized prediction model through COX regression, depicted as a nomogram, offering predictions for CI development in 5, 8, and 12 years among cognitively unimpaired (CU) individuals.

Results:

After excluding CI patients at baseline, our study included 816 participants with complete baseline and follow-up data. The CU group had a mean age of 66.1±6.7 years, with 36.37% males, while the CI group had an average age of 70.3±9.0 years, with 39.20% males. The final model incorporated glial fibrillary acidic protein, Verbal Fluency Test and SCI, and an AUC of 0.8773 (0.792–0.963).

Conclusions:

In conclusion, the sleep-cognition nomogram we developed could successfully predict the risk of converting to CI in elderly participants and could potentially guide the design of interventions for rehabilitation and/or cognitive enhancement to improve the living quality for healthy older adults, detect at-risk individuals, and even slow down the progression of AD.
Circulating Cell Free DNA and DNA Double-Strand Breakage in Alzheimer’s Disease
Authors: Nguyen Michelle , Wood Colby , Rios Andres , Salter Zach , Reddy P. Hemachandra
Published: April 2024

Alzheimer’s disease (AD) is an age-related neurodegenerative disease that is characterized by memory loss and multiple cognitive impairments. AD is pathologically characterized by age-dependent accumulation of amyloid-β protein and the phosphorylation of tau protein in the brains of patients with AD. Clinically, manifestations of AD include cognitive decline, dementia, alterations of high-order brain functions, and movement disorders. Double-stranded DNA breaks are a lethal form of DNA damage and are typically repaired via non-homologous end joining and homologous recombination. However, in AD brain, repair mechanism is disrupted, leading to a cascade of events, cognitive dysfunction, organ failure and reduced lifespan. Increased circulating cell-free DNA in the blood, cerebrospinal fluid, and urine in patients with AD, can be used as early detectable biomarkers for AD. The purpose of our article is to explore the potential uses of cell-free DNA and double-stranded DNA breaks as prognostic markers for AD and examine the recent research on the application of these markers in studies.
The effects of neuro-vestibular-ocular exercises and myofascial release on proprioception and performance in football players with chronic ankle instability
Authors: Kocakılıç Büşra , Çil Elif Tuğçe
Published: April 2024

BACKGROUND AND PURPOSE:

Football players often use quick change of direction, sudden acceleration and explosive movements. This is why chronic ankle instability is one of the most common conditions affecting this athlete population. This study investigates the effects of neuro-vestibular-ocular exercises and myofascial release on proprioception and performance in football players with chronic ankle instability.

MATERIALS AND METHODS:

This randomized controlled clinical trial included 60 football players aged 18–30. The players were randomly divided into two groups. The first group (NVOEG, [Formula: see text]30) was included in the Neuro-Vestibular-ocular exercise training program, while the myofascial release was applied to the second group (MRHOG, [Formula: see text]30). Both protocols were applied for eight weeks. The participants’ Cumberland Ankle Instability Tool (CAIT) scores were assessed before and after the intervention. Proprioception was evaluated by using the joint position sense test. Additionally, kick speed (KS), 30-m sprint, zig-zag agility test (ZAT) and Landing error score system (LESS) tests were applied to evaluate their performance.

RESULTS:

Post-rehabilitation scores showed significant differences in proprioception and performance parameters compared to pre-scores in both groups. (p<0.05). Significant differences were observed between the NVOEG and MRHOG in the post-test scores, including CAIT for unstable and stable ankle, proprioception for unstable ankle, LESS, ZAT with ball performance, and 30-meter sprint test.

CONCLUSIONS:

The neuro-vulvular-ocular exercise training protocol had superior results in terms of proprioception and performance parameters in chronic ankle instability management for football players.
Feasibility of Somato-Cognitive Coordination Therapy Using Virtual Reality for Patients with Advanced Severe Parkinson’s Disease
Authors: Hara Masahiko , Murakawa Yuichiro , Wagatsuma Tomomi , Shinmoto Keito , Tamaki Masatake
Published: April 2024

This feasibility study enrolled 20 patients with advanced severe Parkinson’s disease (PD) to evaluate somato-cognitive coordination therapy (SCCT) using virtual reality. Focusing on the safety and tolerability of SCCT, 17 patients (76±9 years old and 64.7% male) completed the 3-month trial. Key observations included absence of adverse events and tolerability of the participants to SCCT despite initial apprehensions and minor adjustments in medication. Physical functions showed no significant deterioration, suggesting the safety of SCCT. In conclusion, SCCT emerges as feasible and well-tolerated intervention in advanced severe PD, requiring further research to assess its therapeutic efficacy.
A user-friendly deep learning application for accurate lung cancer diagnosis
Authors: Tai Duong Thanh , Nhu Nguyen Tan , Tuan Pham Anh , Sulieman Abdelmoneim , Omer Hiba , Alirezaei Zahra , Bradley David , Chow James C.L.
Published: April 2024

BACKGROUND:

Accurate diagnosis and subsequent delineated treatment planning require the experience of clinicians in the handling of their case numbers. However, applying deep learning in image processing is useful in creating tools that promise faster high-quality diagnoses, but the accuracy and precision of 3-D image processing from 2-D data may be limited by factors such as superposition of organs, distortion and magnification, and detection of new pathologies. The purpose of this research is to use radiomics and deep learning to develop a tool for lung cancer diagnosis.

METHODS:

This study applies radiomics and deep learning in the diagnosis of lung cancer to help clinicians accurately analyze the images and thereby provide the appropriate treatment planning. 86 patients were recruited from Bach Mai Hospital, and 1012 patients were collected from an open-source database. First, deep learning has been applied in the process of segmentation by U-NET and cancer classification via the use of the DenseNet model. Second, the radiomics were applied for measuring and calculating diameter, surface area, and volume. Finally, the hardware also was designed by connecting between Arduino Nano and MFRC522 module for reading data from the tag. In addition, the displayed interface was created on a web platform using Python through Streamlit.

RESULTS:

The applied segmentation model yielded a validation loss of 0.498, a train loss of 0.27, a cancer classification validation loss of 0.78, and a training accuracy of 0.98. The outcomes of the diagnostic capabilities of lung cancer (recognition and classification of lung cancer from chest CT scans) were quite successful.

CONCLUSIONS:

The model provided means for storing and updating patients’ data directly on the interface which allowed the results to be readily available for the health care providers. The developed system will improve clinical communication and information exchange. Moreover, it can manage efforts by generating correlated and coherent summaries of cancer diagnoses.
Scope and challenges of mind-brain relationships in the context of the dialogue between neuroscience and philosophy
Authors: Giménez Amaya J.M. , Lombo J.A.
Published: April 2024

The so-called «mind-brain relationships» are shown to be a privileged place for understanding the human being in a unitary way in its biological and psychic aspects. This reveals the need for an interdisciplinary approach to understand the human being in an integral way. This approach can be carried out, at least, in two directions, taking as a model the dialogue between neuroscience and philosophy. The first one goes from neuroscience to philosophy and covers, above all, the subject of knowledge, mainly in the so-called inner senses. The second extends from philosophy to neuroscience by exploring topics such as attention, memory and habits. From this vision, an understanding of mind-brain relationships arises in which the interdisciplinary approach is extremely important. From it, we propose a possible application of these relationships to the ethical sphere, inspired by the philosopher Alasdair MacIntyre in his analysis of human vulnerability in a context of social co-dependence.
On the issue of the history of the formation of the flora of the Aktobe floral district
Authors:   Baishev University, Aipeisova S.A. , Utarbayeva N.A. ,   Aktobe Regional University named after K. Zhubanov, Kazkeev E.T. ,   Aktobe Regional University named after K. Zhubanov
Published: April 2024

The question of the origin and history of flora formation is one of the most important areas of botanical and geographical research. The solution of this issue is possible only on the basis of materials from paleobotany, paleogeography, paleogeology, phytostratigraphy, paleoclimatology, paleontology, as well as the identification and study of relict plant species of flora. The purpose of the work is to consider the main stages of the genesis of the flora of the Aktobe floral district. The urgency of the problem is due to the need to develop theoretical problems of phlorogenesis and phytocenogenesis and to reflect them on a specific regional material. The work was carried out on the basis of literature data on the genesis of flora, geomorphology and climatology, as well as on long-term herbarium materials collected by us using the route method. The analysis of the areas of relict species of the study area demonstrates the pronounced connections of flora with the forest, forest-steppe, steppe zones of Europe, Siberia, the Turan deserts, mountainous Central Asia, as well as the presence of certain connections with the Caucasus, the Mediterranean and once again confirms the duality of the nature of the steppes: on the one hand from the light-tolerant species of the Arctic-tertiary root, and on the other the sides are from the ancient Mediterranean". The study of materials on paleobotany, paleogeography, paleogeology, phytostratigraphy, paleoclimatology and the analysis of relics reflect the complexity and heterogeneity and heterochronicity of the process of florogenesis of the Aktobe floristic district.
Study of Cladonia species growing in various areas of Burabai Park
Authors:   Alikhan Bokeikhan University, Bukabayeva Zh.T. , Silybayeva B.M. ,   Alikhan Bokeikhan University, Akhmetzhanova A.M. ,   Alikhan Bokeikhan University, Anuarbekova A.N. ,   Alikhan Bokeikhan University
Published: April 2024

Studies of the lichen flora of the Burabai National Park were carried out in 2018-2022 in spring, summer and autumn by a route expedition. Depending on the purpose of the research work, the national park was divided into 11 sections. By using the mapping scheme of lichen species obtained as a research object, it was found that out of 11 sites of the Cladoniaceae family, 18 species grow only on 7 sites. Among them, Cladonia fimbriata, C.pyxidata, C. Cenotea, C. tenius, C. sulvatica, C. gracilis, C. alpestris were distinguished from other species by their distribution in several areas. In the study of the route, the frequency of occurrence of the lichen species, ecology, intrauterine form and features of reproduction were considered. Along with the determinants, a scanning electron microscope (JSM) was used to determine the types of cladonia. Among the 18 species of cladonia belonging to the genus Cladonia, only a few individuals were found at the Zolotobor site among the research sites of the Cladonia coccifera. In this regard, the species of Coccifer cladonia was bred on the territory of the Burabai National Park as a species with a very low frequency of occurrence and in need of protection. The podecia of the epigeal Cladonia alpestris, which inhabited this area of the Burabai Park, spread over large territories. In this regard, it has been established that it grows in almost all areas of the National Garden in comparison with other species belonging to this genus. The free location of their substructural thallomas on the soil surface indicates that the species Cladonia alpestris is mainly due to the peculiarities of reproduction by vegetative pathways. In this regard, Cladonia alpestris was considered as the dominant species in comparison with other species of cladonia growing in the Burabai National Park.
Analysis of Gait Pattern Affected by Various Disease : A Review
Authors: Birambole Nikita , Pratima Salunkhe
Published: April 2024

Gait is pattern of walking of individual, is unique pattern of a person. The gait pattern is affected by various disease, ill condition of a person. In this review article we discuss about various diseases by which gait of an individual gets affected. Some disease are ; Parkinson's disease (PD) is a degenerative brain disorder causing shuffled gait, impaired balance, and freezing of gait. Morquio A syndrome, a group of disorders called mucopolysaccharidosis, can lead to vision, hearing, bone, brain, and heart problems. The anterior cruciate ligament (ACL) is a key stabilizer in the knee, and a torn ACL can cause instability when walking or changing directions. Examination of the gait pattern of a those person who having a disease such as ; Parkinson’s disease, Morquio A syndrome, Anterior Crucial Ligament, etc. In normal human the Gait Cycle has two phases ; Stance and swing phase. The stance phase covers approx 60% gait cycle and swing phase covers remaining 40% of gait cycle. In further studies we can analysis on how this cycle varies in abnormal walking.These review article summarises about gait pattern affected by various diseases. Study of gait pattern used for solving criminal cases as we can recognize various abnormalities a person may have by the analysis of his or her gait pattern. It is used as secondary evidence. By using gait pattern we can find out individuals age, sex, and height.
КОМПЛАЄНС-ПОЛІТИКА БАНКІВ УКРАЇНИ НА СУЧАСНОМУ ЕТАПІ
Authors: Грудзевич Уляна , Пилипенко Соломія , Огінок Соломія
Published: April 2024

Стаття присвячена актуальним питанням розвитку комплаєнсу в банках України. Визначено підходи до законодавчо-нормативного регулювання «комплаєнсу» та його організації в банках. Проаналізовано та систематизовано політики комплаєнсу у відповідності з рекомендаціями Базельського комітету з банківського нагляду: «Комплаєнс і комплаєнс функція в банках». Досліджено практику вітчизняних банків щодо впровадження основних політик комплаєнсу, зокрема, політики Кодексу корпоративної етики, Політики Know Your Costomer, протидії легалізації доходів, одержаних незаконним шляхом і фінансуванню тероризму, Політики боротьби з шахрайством. Окреслено переваги впровадження комплаєнсу для банків, їх власників та клієнтів а також визначено загрози невідповідності політикам комплаєнсу для банківської установи.
ОСОБЛИВОСТІ РОЗВИТКУ ІНТЕРНЕТ-МАРКЕТИНГУ ЗА УМОВ ЄВРОІНТЕГРУВАННЯ
Authors: Кузяк Вікторія , Брейтер Володимир
Published: April 2024

В статті аналізуються та досліджуються проблеми, перспективи розвитку інтернет-маркетингу за умов євроінтегрування. Метою статті є дослідження проблем і перспектив розвитку інтернет-маркетингу вітчизняними підприємствами за умов євроінтегрування економіки країни. Проведено аналізування динаміки чисельності інтернет-користувачів у світі, динаміку, прогноз чисельності інтернет-користувачів соціальних мереж у світі, як потенційних споживачів інтернет-маркетингу. Наведено порівняльну характеристику традиційного маркетингу та сучасного інтернет-маркетингу, виокремлено переваги останнього. Досліджено світові тренди розвитку інтернет-маркетингу за євроінтеграційних умов. (поєднання переваг штучного інтелекту із людським ресурсом, фокусування на застосуванні мобільних технологій, оптимізуванні корпоративних сайтів, проведення репутаційних заходів тощо).
ТЕНДЕНЦІЇ ДОСЛІДЖЕННЯ УПРАВЛІННЯ РИЗИКАМИ ПІДПРИЄМСТВА: БІБЛІОМЕТРИЧНИЙ АНАЛІЗ
Authors: Сова Олександр
Published: April 2024

Потреба в ефективному управлінні ризиками підприємства (Enterprise Risk Management, ERM) актуальна в Україні в наш час, оскільки всі підприємства стикаються з проблемами викликаними війною. За допомогою програмного забезпечення VOSviewer, проведено бібліометричний контент-аналіз досліджень щодо ERM на основі ключових слів, цитувань, географічного розподілу та авторства, зібраних із бази даних Web of Science Core Collection. Отримані результати показують, що існують чотири основні сфери наукового інтересу в галузі досліджень ERM. Це підкреслює значення ефективного управління ризиками для підприємств, які прагнуть збільшити свою загальну ефективність.
МОНІТОРИНГ КЕЙСІВ НЕЕФЕКТИВНОГО (НЕРАЦІОНАЛЬНОГО, НЕЦІЛЬОВОГО) ВИКОРИСТАННЯ КОШТІВ ГРОМАДАМИ ЛУГАНСЬКОЇ ОБЛАСТІ У ЧАС ВІЙНИ У 2022-2023 рр.
Authors: Вартанова Олена , Бузько Ірина , Бурбело Сергій
Published: April 2024

У статті розглянуто методичні засади моніторингу ефективності (раціо-нальності, доцільності) використання коштів громадами, який ґрунтується на аналізі витрат бюджетних коштів громадами, їх розмірі, відповідності цілям діяльності громади (доцільність використання), конкурентоспроможності ці-ни та виконавця, відповідності масштабам діяльності громади тощо. Визна-чено критерії неефективності (нераціональності, недоцільності) використання коштів громадами, зокрема, сумнівність тендеру, відсутність кричної потре-би у закупівлі під час війни, відсутність обґрунтованої потреби у закупівлі, невідповідність кількісних та фінансових параметрів закупівлі масштабу дія-льності громади, завищена ціна, неринкові ціни, неврахування аналогів то-варів і послуг, критична кількість учасників державних тендерів, наявність дискримінаційних вимог у тендері, антиконкурентні дії замовників та підряд-ників тощо. Представлено результати моніторингу 31 окремих кейсів неефективно-го (нераціонального, недоцільного) використання коштів громадами Луган-ської області у час війни у 2022-2023 рр. Результати проведення моніторингу ефективності (раціональності, до-цільності) використання коштів громадами в час війни є важливим кроком у впровадженні ефективного управління витратами бюджетних коштів, підви-щує прозорість цього процесу, забезпечує оптимальне співвідношення між витратами та досягнутими результатами, надає рекомендації щодо подаль-шого використання коштів громадами.
ЗЕЛЕНІ ІНВЕСТИЦІЇ ТА ЇХ ЗНАЧЕННЯ У ПОВОЄННОМУ ВІДНОВЛЕННІ УКРАЇНИ
Authors: Пристемський О.С. , Єфремов А.О.
Published: April 2024

В статті було досліджено екологічний вектор розвитку української економіки, як необхідний та важливий фактор майбутнього повоєнного відновлення і розвитку. Так, було розглянуто цілі Європейського Зеленого Курсу в контексті активних зусиль задля інтеграції та вступу в Європейський Союз. Окрім цього, статтею було визначено та детально розглянуто такі напрями розвитку зелених технологій в Україні, як: виробництво біометану, виробництво водню, зелена енергетика, будівництво систем зрошення в регіонах, які страждають від посухи та зелена аграрна логістика. Так, стало зрозумілим, що Урядом країни передбачається інноваційне повоєнне відновлення, на основі значних інвестицій у зелені технології, що сприятиме підвищенню репутації країни на міжнародній арені та міжнародній фінансовій підтримці. Окрім цього, було досліджено низку проблем, з якими стикаються українські стартапери та малі підприємства на початку своєї підприємницької діяльності, що дало змогу розробити рекомендації задля максимально ефективного розвитку української економіки.
КОНКУРЕНТОСПРОМОЖНІСТЬ АГРАРНИХ ПІДПРИЄМСТВ: СУТНІСТЬ ТА НАПРЯМКИ ЗМІЦНЕННЯ
Authors: Строченко Н.І. , Ковальова О.М.
Published: April 2024

Враховуючи постійні зміни у зовнішньому середовищі та появу все нових чинників, що впливають на діяльність аграрних підприємств, проблема пошуку напрямів зміцнення конкурентоспроможності аграрних підприємств залишається актуальною. Метою статті є визначення та поглиблення сутності конкурентоспроможності аграрних підприємств, формування системи факторів формування конкурентоспроможності аграрного підприємства та напрямів її зміцнення. В статті представлено систему факторів формування конкурентоспроможності аграрного підприємства. Для аналізу конкурентоспроможності аграрних підприємств в статті використано методику SWOT-аналізу. Для зміцнення конкурентоспроможності аграрних підприємств запропоновано: удосконалення механізму державної підтримки, впровадження ефективних підприємницьких стратегій розвитку аграрних підприємств та ін. Отримані висновки матимуть практичне значення для аграрних підприємств при розробці стратегій зміцнення конкурентоспроможності.