bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 1 from Human Melanoma Metastases Demonstrate Nonstochastic Site-Specific Antigen Heterogeneity That Correlates with T-cell Infiltration
Authors: Bartlett Edmund K. , Fetsch Patricia A. , Filie Armando C. , Abati Andrea , Steinberg Seth M. , Wunderlich John R. , White Donald E. , Stephens Daniel J. , Marincola Francesco M. , Rosenberg Steven A. , Kammula Udai S.
Published: April 2023

PDF file - 57K, Pairwise comparison of antigen expression by individual anatomic site. Shown are p value results of Cochran-Armitage test for trend. p <0.005 considered significant (bold, underlined), p <0.05-0.005 considered a trend (bold).
Supplementary Figure 2 from Human Melanoma Metastases Demonstrate Nonstochastic Site-Specific Antigen Heterogeneity That Correlates with T-cell Infiltration
Authors: Bartlett Edmund K. , Fetsch Patricia A. , Filie Armando C. , Abati Andrea , Steinberg Seth M. , Wunderlich John R. , White Donald E. , Stephens Daniel J. , Marincola Francesco M. , Rosenberg Steven A. , Kammula Udai S.
Published: April 2023

PDF file - 65K, TYR expression varies with the degree of CD8+ and CD4+ T cell infiltrate. (A) The distribution of antigen expression for given CD8 (blue) infiltrate score (0-3+, column). (B) The distribution of antigen expression for given CD4 (green) infiltrate score (0-3+, column).
Supplementary Tables 1 - 3 from Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers
Authors: Di Caro Giuseppe , Bergomas Francesca , Grizzi Fabio , Doni Andrea , Bianchi Paolo , Malesci Alberto , Laghi Luigi , Allavena Paola , Mantovani Alberto , Marchesi Federica
Published: April 2023

PDF file - 108K, Table S1. Patients' demographics and clinico-pathologic features. Table S2. Patients' demographics and clinico-pathologic features according to TLT density. Table S3. Univariate and Multivariate Cox hazard model for predictive factors of disease relapse.
Supplementary Text from Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer
Authors: Yi Joo Mi , Guzzetta Angela A. , Bailey Vasudev J. , Downing Stephanie R. , Van Neste Leander , Chiappinelli Katherine B. , Keeley Brian P. , Stark Alejandro , Herrera Alexander , Wolfgang Christopher , Pappou Emmanouil P. , Iacobuzio-Donahue Christine A. , Goggins Michael G. , Herman James G. , Wang Tza-Huei , Baylin Stephen B. , Ahuja Nita
Published: April 2023

- PDF file 93K, This includes figure legends of supplementary Figure S1-S3
Supplemental Figure 2 from Influence of Human OATP1B1, OATP1B3, and OATP1A2 on the Pharmacokinetics of Methotrexate and Paclitaxel in Humanized Transgenic Mice
Authors: van de Steeg Evita , van Esch Anita , Wagenaar Els , Kenworthy Kathryn E. , Schinkel Alfred H.
Published: April 2023

PDF file - 159K,Immunohistochemical staining of OATP1B3 in kidneys of humanized transgenic OATP1B3 mice
Supplementary Figure 1 from Direct Inhibition of Retinoblastoma Phosphorylation by Nimbolide Causes Cell-Cycle Arrest and Suppresses Glioblastoma Growth
Authors: Karkare Swagata , Chhipa Rishi Raj , Anderson Jane , Liu Xiaona , Henry Heather , Gasilina Anjelika , Nassar Nicholas , Roychoudhury Jayeeta , Clark Jason P , Kumar Ashish , Pauletti Giovanni M. , Ghosh Pradip K. , Dasgupta Biplab
Published: April 2023

PDF file - 312K, Nimbolide is more cytotoxic than many other chemotherapy agents. (A) Cell proliferation assay showing viability of GBM cells in the presence of Temozolomide (TMZ) for 72 hours. (B) Cell proliferation assay showing the cytotoxic effect of Nimbolide in comparison with other chemotherapeutic agents. Data is representative of two independent experiments. +p ≤ 0.05; *p ≤ 0.001.
Supplementary Figure S1 from GKN1–miR-185–DNMT1 Axis Suppresses Gastric Carcinogenesis through Regulation of Epigenetic Alteration and Cell Cycle
Authors: Yoon Jung Hwan , Choi Yoo Jin , Choi Won Suk , Ashktorab Hassan , Smoot Duane T. , Nam Suk Woo , Lee Jung Young , Park Won Sang
Published: April 2023

Supplementary Figure S1 - PDF file 37K, Effects of GKN1 on cell growth and proliferation in MKN1 and MKN28 cells
Supplementary Document from GKN1–miR-185–DNMT1 Axis Suppresses Gastric Carcinogenesis through Regulation of Epigenetic Alteration and Cell Cycle
Authors: Yoon Jung Hwan , Choi Yoo Jin , Choi Won Suk , Ashktorab Hassan , Smoot Duane T. , Nam Suk Woo , Lee Jung Young , Park Won Sang
Published: April 2023

Supplementary Document - PDF file 159K, Supplemental document including Supplemental Table, Figure legends, material & methods and refference
Supplementary Figure 1 from Phase II Trial of Bicalutamide in Patients with Androgen Receptor–Positive, Estrogen Receptor–Negative Metastatic Breast Cancer
Authors: Gucalp Ayca , Tolaney Sara , Isakoff Steven J. , Ingle James N. , Liu Minetta C. , Carey Lisa A. , Blackwell Kimberly , Rugo Hope , Nabell Lisle , Forero Andres , Stearns Vered , Doane Ashley S. , Danso Michael , Moynahan Mary Ellen , Momen Lamia F. , Gonzalez Joseph M. , Akhtar Arooj , Giri Dilip D. , Patil Sujata , Feigin Kimberly N. , Hudis Clifford A. , Traina Tiffany A.
Published: April 2023

Supplementary Figure 1 - PDF file 44K, Supplementary Figure 1A-D. Median hormone levels at baseline, C2 and EOS
Supplementary Figure 1 from Bazedoxifene Exhibits Antiestrogenic Activity in Animal Models of Tamoxifen-Resistant Breast Cancer: Implications for Treatment of Advanced Disease
Authors: Wardell Suzanne E. , Nelson Erik R. , Chao Christina A. , McDonnell Donald P.
Published: April 2023

PDF file - 159K, Immunoblot loading controls for images included within Figure 4.
Supplementary Table 2 from Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment
Authors: Garralda Elena , Paz Keren , López-Casas Pedro P. , Jones Siân , Katz Amanda , Kann Lisa M. , López-Rios Fernando , Sarno Francesca , Al-Shahrour Fátima , Vasquez David , Bruckheimer Elizabeth , Angiuoli Samuel V. , Calles Antonio , Diaz Luis A. , Velculescu Victor E. , Valencia Alfonso , Sidransky David , Hidalgo Manuel
Published: April 2023

PDF file - 57KB, Avatar treatment results.
Supplementary Table 1 from Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment
Authors: Garralda Elena , Paz Keren , López-Casas Pedro P. , Jones Siân , Katz Amanda , Kann Lisa M. , López-Rios Fernando , Sarno Francesca , Al-Shahrour Fátima , Vasquez David , Bruckheimer Elizabeth , Angiuoli Samuel V. , Calles Antonio , Diaz Luis A. , Velculescu Victor E. , Valencia Alfonso , Sidransky David , Hidalgo Manuel
Published: April 2023

PDF file - 802KB, Somatic mutations and Copy number variations.
Supplementary Table 1 from Surveillance of the Tumor Mutanome by T Cells during Progression from Primary to Recurrent Ovarian Cancer
Authors: Wick Darin A. , Webb John R. , Nielsen Julie S. , Martin Spencer D. , Kroeger David R. , Milne Katy , Castellarin Mauro , Twumasi-Boateng Kwame , Watson Peter H. , Holt Rob A. , Nelson Brad H.
Published: April 2023

PDF file - 68K, Tested minimal peptides and corresponding MHC binding scores for Patient 1.
Supplementary Figure 5 from Surveillance of the Tumor Mutanome by T Cells during Progression from Primary to Recurrent Ovarian Cancer
Authors: Wick Darin A. , Webb John R. , Nielsen Julie S. , Martin Spencer D. , Kroeger David R. , Milne Katy , Castellarin Mauro , Twumasi-Boateng Kwame , Watson Peter H. , Holt Rob A. , Nelson Brad H.
Published: April 2023

PDF file - 159K, Flow cytometric assessment of the prevalence of Vβ13.6 in TAL from Patient 3.
Figure S1 from Multiple Myeloma Patients Have a Specific Serum Metabolomic Profile That Changes after Achieving Complete Remission
Authors: Puchades-Carrasco Leonor , Lecumberri Ramón , Martínez-López Joaquín , Lahuerta Juan-José , Mateos María-Victoria , Prósper Felipe , San-Miguel Jesús F. , Pineda-Lucena Antonio
Published: April 2023

Figure S1 - PDF file 47K, Principal Component Analyses (PCA) of 1H-NMR spectra corresponding to all the samples included in the study colored according to (A) gender (full triangles: male, empty triangles: female) and (B) age (full triangles: >70 years, empty triangles: 60-70 years, full squares: 50-60 years, empty squares: <50 years)
Supplementary Figure 2 from Surveillance of the Tumor Mutanome by T Cells during Progression from Primary to Recurrent Ovarian Cancer
Authors: Wick Darin A. , Webb John R. , Nielsen Julie S. , Martin Spencer D. , Kroeger David R. , Milne Katy , Castellarin Mauro , Twumasi-Boateng Kwame , Watson Peter H. , Holt Rob A. , Nelson Brad H.
Published: April 2023

PDF file - 248K, Patients 1 and 2 failed to respond to any of the mutant peptides at any of the time points.
Supplementary Tables 1 - 3 from Plasma MicroRNAs as Novel Biomarkers for Endometriosis and Endometriosis-Associated Ovarian Cancer
Authors: Suryawanshi Swati , Vlad Anda M. , Lin Hui-Min , Mantia-Smaldone Gina , Laskey Robin , Lee MinJae , Lin Yan , Donnellan Nicole , Klein-Patel Marcia , Lee Ted , Mansuria Suketu , Elishaev Esther , Budiu Raluca , Edwards Robert P. , Huang Xin
Published: April 2023

PDF file - 36K, Supplementary Table 1. Demographic and clinical characteristics of the study cohort. Supplementary Table 2. List of the 24 miRNAs identified by genome-wide plasma miRNA expression profiling from healthy controls (n=6), endometriosis patients (n=7), and EAOC patients (n=7). Supplementary Table 3. The 10 most differentially expressed miRNAs in pair-wise comparisons between SOC patients and healthy controls, endometriosis, or EAOC samples.
Supplementary Table 2 from AXL Is a Key Regulator of Inherent and Chemotherapy-Induced Invasion and Predicts a Poor Clinical Outcome in Early-Stage Colon Cancer
Authors: Dunne Philip D. , McArt Darragh G. , Blayney Jaine K. , Kalimutho Murugan , Greer Samanda , Wang Tingting , Srivastava Supriya , Ong Chee Wee , Arthur Ken , Loughrey Maurice , Redmond Keara , Longley Daniel B. , Salto-Tellez Manuel , Johnston Patrick G. , Van Schaeybroeck Sandra
Published: April 2023

PDF file - 223K, Univariate and multivariate analyses for OS, DSS, DFS and AXL-LOW and AXL-HIGH in stage II/III CRC group (publicly-available CRC microarray dataset).
Supplementary Table 1 from Interleukin-17A Modulates Circulating Tumor Cells in Tumor Draining Vein of Colorectal Cancers and Affects Metastases
Authors: Tseng Ju-Yu , Yang Chih-Yung , Liang Shu-Ching , Liu Ren-Shyan , Yang Shung-Haur , Lin Jen-Kou , Chen Yuh-Min , Wu Yu-Chung , Jiang Jeng-Kai , Lin Chi-Hung
Published: April 2023

PDF file - 126KB, Clinicopathological characteristics of the patients analyzed in this study.
Supplementary Figure 6 from AXL Is a Key Regulator of Inherent and Chemotherapy-Induced Invasion and Predicts a Poor Clinical Outcome in Early-Stage Colon Cancer
Authors: Dunne Philip D. , McArt Darragh G. , Blayney Jaine K. , Kalimutho Murugan , Greer Samanda , Wang Tingting , Srivastava Supriya , Ong Chee Wee , Arthur Ken , Loughrey Maurice , Redmond Keara , Longley Daniel B. , Salto-Tellez Manuel , Johnston Patrick G. , Van Schaeybroeck Sandra
Published: April 2023

PDF file - 235K, Clinical relevance of AXL in CRC tissues.
Supplementary Figure 7 from Interleukin-17A Modulates Circulating Tumor Cells in Tumor Draining Vein of Colorectal Cancers and Affects Metastases
Authors: Tseng Ju-Yu , Yang Chih-Yung , Liang Shu-Ching , Liu Ren-Shyan , Yang Shung-Haur , Lin Jen-Kou , Chen Yuh-Min , Wu Yu-Chung , Jiang Jeng-Kai , Lin Chi-Hung
Published: April 2023

PDF file - 261KB, MMP9 is up-regulated in the inoculated tumors of IL-17A-depelting mice.
Supplementary Figure 3 from Interleukin-17A Modulates Circulating Tumor Cells in Tumor Draining Vein of Colorectal Cancers and Affects Metastases
Authors: Tseng Ju-Yu , Yang Chih-Yung , Liang Shu-Ching , Liu Ren-Shyan , Yang Shung-Haur , Lin Jen-Kou , Chen Yuh-Min , Wu Yu-Chung , Jiang Jeng-Kai , Lin Chi-Hung
Published: April 2023

PDF file - 46KB, The serum profiles of GM-CSF in mice with or without metastasis.
Supplementary Table 4 from Hypoxia-Driven Gene Expression Is an Independent Prognostic Factor in Stage II and III Colon Cancer Patients
Authors: Dekervel Jeroen , Hompes Daphne , van Malenstein Hannah , Popovic Dusan , Sagaert Xavier , De Moor Bart , Van Cutsem Eric , D'Hoore André , Verslype Chris , van Pelt Jos
Published: April 2023

PDF file - 77KB, Significantly altered pathways found in CaCo-2 cells under chronic hypoxia.
Supplementary Table 3 from Hypoxia-Driven Gene Expression Is an Independent Prognostic Factor in Stage II and III Colon Cancer Patients
Authors: Dekervel Jeroen , Hompes Daphne , van Malenstein Hannah , Popovic Dusan , Sagaert Xavier , De Moor Bart , Van Cutsem Eric , D'Hoore André , Verslype Chris , van Pelt Jos
Published: April 2023

PDF file - 303KB, Top 25 differentially expressed genes under chronic hypoxia in CaCo-2 cells.
Supplementary Table 2 from Hypoxia-Driven Gene Expression Is an Independent Prognostic Factor in Stage II and III Colon Cancer Patients
Authors: Dekervel Jeroen , Hompes Daphne , van Malenstein Hannah , Popovic Dusan , Sagaert Xavier , De Moor Bart , Van Cutsem Eric , D'Hoore André , Verslype Chris , van Pelt Jos
Published: April 2023

PDF file - 91KB, Nanostring nCounter CodeSet for the housekeeping genes, hypoxia signature and TP53.
Supplementary Table 1 from Synergistic Interaction between the HDAC Inhibitor, MPT0E028, and Sorafenib in Liver Cancer Cells In Vitro and In Vivo
Authors: Chen Chun-Han , Chen Mei-Chuan , Wang Jing-Chi , Tsai An-Chi , Chen Ching-Shih , Liou Jing-Ping , Pan Shiow-Lin , Teng Che-Ming
Published: April 2023

PDF file - 60KB, Primer sequences for real-time PCR used in this study.
Supplementary Figure 6 from Personalized Chemotherapy Profiling Using Cancer Cell Lines from Selectable Mice
Authors: Kamiyama Hirohiko , Rauenzahn Sherri , Shim Joong Sup , Karikari Collins A. , Feldmann Georg , Hua Li , Kamiyama Mihoko , Schuler F. William , Lin Ming-Tseh , Beaty Robert M. , Karanam Balasubramanyam , Liang Hong , Mullendore Michael E. , Mo Guanglan , Hidalgo Manuel , Jaffee Elizabeth , Hruban Ralph H. , Jinnah H.A. , Roden Richard B.S. , Jimeno Antonio , Liu Jun O. , Maitra Anirban , Eshleman James R.
Published: April 2023

PDF file - 77K, Chemosensitivity to topoisomerase inhibitors.
Supplementary Figure 2 from First-in-Human Phase I Trial of Two Schedules of OSI-930, a Novel Multikinase Inhibitor, Incorporating Translational Proof-of-Mechanism Studies
Authors: Yap Timothy A. , Arkenau Hendrik-Tobias , Camidge D. Ross , George Suzanne , Serkova Natalie J. , Gwyther Stephen J. , Spratlin Jennifer L. , Lal Rohit , Spicer James , Desouza Nandita M. , Leach Martin O. , Chick Jon , Poondru Srinivasu , Boinpally Ramesh , Gedrich Richard , Brock Katie , Stephens Andrew , Eckhardt S. Gail , Kaye Stan B. , Demetri George , Scurr Michelle
Published: April 2023

PDF file - 39K, Association of sVEGFR2 changes and steady state OSI-930 levels at the end of the first 21-day dosing cycle in the 500mg BID expansion cohort
Supporting Figure 4 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Authors: Qiu Yunping , Cai Guoxiang , Zhou Bingsen , Li Dan , Zhao Aihua , Xie Guoxiang , Li Houkai , Cai Sanjun , Xie Dong , Huang Changzhi , Ge Weiting , Zhou Zhanxiang , Xu Lisa X. , Jia Weiping , Zheng Shu , Yen Yun , Jia Wei
Published: April 2023

PDF file 133K, ROC and Kaplan-Meier curves for survival analysis in samples from Shanghai using the ratio of hypoxanthine to aspartate
Supporting Figure 3 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Authors: Qiu Yunping , Cai Guoxiang , Zhou Bingsen , Li Dan , Zhao Aihua , Xie Guoxiang , Li Houkai , Cai Sanjun , Xie Dong , Huang Changzhi , Ge Weiting , Zhou Zhanxiang , Xu Lisa X. , Jia Weiping , Zheng Shu , Yen Yun , Jia Wei
Published: April 2023

PDF file 145K, Fold change bar plot of differentially expressed genes between CRC tissues and adjacent normal ones; and diagnostic results in four batches of CRC samples and gastric cardiac cancer
Supplementary Table 1, Figure 1 from The Proteasome Inhibitor Carfilzomib Functions Independently of p53 to Induce Cytotoxicity and an Atypical NF-κB Response in Chronic Lymphocytic Leukemia Cells
Authors: Gupta Sneha V. , Hertlein Erin , Lu Yanhui , Sass Ellen J. , Lapalombella Rosa , Chen Timothy L. , Davis Melanie E. , Woyach Jennifer A. , Lehman Amy , Jarjoura David , Byrd John C. , Lucas David M.
Published: April 2023

PDF file - 82K, Supplementary Table 1: Fold changes of NF-κB target genes in CLL: CLL cells (n=12) were treated with 300 nM CFZ (1 hr), 1.7 �M CpG (4 hr) or 500 ng/ml CD40L (4 hr). RNA was extracted at 8 hr from CFZ treated samples and mRNA expression was analyzed using real-time RT-PCR. Cells highlighted in light grey have estimated fold changes > 2 and were significant at the (unadjusted) α=0.05 level of significance. Cells highlighted in dark grey are significant at the α=0.05 level, but have estimated fold changes < 2. Supplementary Figure 1: Selection of 697 cells to generate p53DN cells: Jeko, MEC-1 and 697 cells (n=3) were exposed to 0, 300 nM CFZ for 1 hr and 5 Gy gamma irradiation. (S1A) Viability was assessed by MTS assay at 48 hrs and results were calculated relative to time-matched samples untreated samples. (S1B) Whole cell lysates and RNA were collected at 8 hr and were immunoblotted for indicated proteins using GAPDH as a loading control. (S1C) Changes in transcription of p53 and subsequent targets were assessed by real-time RT-PCR.
Supporting Figure 1 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Authors: Qiu Yunping , Cai Guoxiang , Zhou Bingsen , Li Dan , Zhao Aihua , Xie Guoxiang , Li Houkai , Cai Sanjun , Xie Dong , Huang Changzhi , Ge Weiting , Zhou Zhanxiang , Xu Lisa X. , Jia Weiping , Zheng Shu , Yen Yun , Jia Wei
Published: April 2023

PDF file 104K, PCA scores plot, permutation test and representative chromatograms for samples collected from Shanghai
Supplementary Figure Legend from The Proteasome Inhibitor Carfilzomib Functions Independently of p53 to Induce Cytotoxicity and an Atypical NF-κB Response in Chronic Lymphocytic Leukemia Cells
Authors: Gupta Sneha V. , Hertlein Erin , Lu Yanhui , Sass Ellen J. , Lapalombella Rosa , Chen Timothy L. , Davis Melanie E. , Woyach Jennifer A. , Lehman Amy , Jarjoura David , Byrd John C. , Lucas David M.
Published: April 2023

PDF file - 183K
Supplementary Figures from The Mechanism of DAB2IP in Chemoresistance of Prostate Cancer Cells
Authors: Wu Kaijie , Xie Daxing , Zou Yonglong , Zhang Tingting , Pong Rey-Chen , Xiao Guanghua , Fazli Ladan , Gleave Martin , He Dalin , Boothman David A. , Hsieh Jer-Tsong
Published: April 2023

Supplementary Figures - Supplementary Figures - PDF file 1005K, Fig S1. DAB2IP knockdown enhances Egr1 and sCLU expression. Fig S2. Wnt treatment enhances sCLU expression and Egr1 promoter activity in prostate cells. Fig S3. Wnt/beta-catenin regulates production of the IGF-1-sCLU expression axis. Fig S4. Deletion of NF-{kappa}B binding sites within the Egr1 promoter has no effect on its repression by DAB2IP. Fig S5. Egr1 and sCLU protein expression increased in PCa tissues following androgen-deprived therapy
Supplementary Figure 6 from Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib
Authors: Furmanski Brian D. , Hu Shuiying , Fujita Ken-ichi , Li Lie , Gibson Alice A. , Janke Laura J. , Williams Richard T. , Schuetz John D. , Sparreboom Alex , Baker Sharyn D.
Published: April 2023

PDF file - 144K, Influence of Abcc4 on aspirin transport.
Supplementary Figure Legends from Phase I Safety, Pharmacokinetic and Pharmacodynamic Evaluation of the Vascular Disrupting Agent Ombrabulin (AVE8062) in Patients with Advanced Solid Tumors
Authors: Sessa Cristiana , Lorusso Patricia , Tolcher Anthony , Farace Françoise , Lassau Nathalie , Delmonte Angelo , Braghetti Antonio , Bahleda Rastislav , Cohen Patrick , Hospitel Marie , Veyrat-Follet Christine , Soria Jean-Charles
Published: April 2023

Supplementary Figure Legends - PDF file 62K, Supplementary Figure legends
Supplementary Figure 4 from Caspase-Independent Cell Death Is Involved in the Negative Effect of EGF Receptor Inhibitors on Cisplatin in Non–Small Cell Lung Cancer Cells
Authors: Yamaguchi Hirohito , Hsu Jennifer L. , Chen Chun-Te , Wang Ying-Nai , Hsu Ming-Chuan , Chang Shih-Shin , Du Yi , Ko How-Wen , Herbst Roy , Hung Mien-Chie
Published: April 2023

PDF file - 35K, The effects of cisplatin and/or gefitinib on A549-Bcl-XL tumor growth in vivo
Supplementary Figure 10 from Caspase-Independent Cell Death Is Involved in the Negative Effect of EGF Receptor Inhibitors on Cisplatin in Non–Small Cell Lung Cancer Cells
Authors: Yamaguchi Hirohito , Hsu Jennifer L. , Chen Chun-Te , Wang Ying-Nai , Hsu Ming-Chuan , Chang Shih-Shin , Du Yi , Ko How-Wen , Herbst Roy , Hung Mien-Chie
Published: April 2023

PDF file - 39K, The effects of cisplatin, SAHA, and erastin alone or in combination on cellular ROS levels
Supplementary Figure 1 from A Novel Aldehyde Dehydrogenase-3 Activator (Alda-89) Protects Submandibular Gland Function from Irradiation without Accelerating Tumor Growth
Authors: Xiao Nan , Cao Hongbin , Chen Che-Hong , Kong Christina S. , Ali Rehan , Chan Cato , Sirjani Davud , Graves Edward , Koong Albert , Giaccia Amato , Mochly-Rosen Daria , Le Quynh-Thu
Published: April 2023

PDF file, 89K, Low dose of Alda-89 does not protect SMG Function after RT.
Supplementary Table 1 from The PAM50 Risk-of-Recurrence Score Predicts Risk for Late Distant Recurrence after Endocrine Therapy in Postmenopausal Women with Endocrine-Responsive Early Breast Cancer
Authors: Filipits Martin , Nielsen Torsten O. , Rudas Margaretha , Greil Richard , Stöger Herbert , Jakesz Raimund , Bago-Horvath Zsuzsanna , Dietze Otto , Regitnig Peter , Gruber-Rossipal Christine , Müller-Holzner Elisabeth , Singer Christian F. , Mlineritsch Brigitte , Dubsky Peter , Bauernhofer Thomas , Hubalek Michael , Knauer Michael , Trapl Harald , Fesl Christian , Schaper Carl , Ferree Sean , Liu Shuzhen , Cowens J. Wayne , Gnant Michael
Published: April 2023

PDF file - 34K, Supplementary Table S1. ROR cutoff values for risk groups defined by nodal status.
Supplementary Information from Regulation of Cell Proliferation and Migration by Keratin19-Induced Nuclear Import of Early Growth Response-1 in Breast Cancer Cells
Authors: Ju Ji-hyun , Yang Wonseok , Lee Kyung-min , Oh Sunhwa , Nam KeeSoo , Shim Sarah , Shin Soon Young , Gye Myung Chan , Chu In-Sun , Shin Incheol
Published: April 2023

Supplementary Information - PDF file 163K, Legends to Supplementary data and Materials and Methods
Supplementary Tables from Identification of Multiple Mechanisms of Resistance to Vemurafenib in a Patient with BRAFV600E-Mutated Cutaneous Melanoma Successfully Rechallenged after Progression
Authors: Romano Emanuela , Pradervand Sylvain , Paillusson Alexandra , Weber Johann , Harshman Keith , Muehlethaler Katja , Speiser Daniel , Peters Solange , Rimoldi Donata , Michielin Olivier
Published: April 2023

Supplementary Tables - PDF file 61K, This file contains Supplementary Tables: Suppl. Table 1. Somatic single nucleotide substitution spectrum. Suppl. Table 2. Somatic single nucleotide substitution frequencies. Suppl. Table 3. Cancer genes in aneuploidy regions. Suppl. Table 4. RNA-seq log2 normalized gene counts for genes belonging to tyrosine kinase receptor family, RAS/MAPK and AKT/mTOR signaling pathways
Supplementary Figure 2 from The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas
Authors: Gini Beatrice , Zanca Ciro , Guo Deliang , Matsutani Tomoo , Masui Kenta , Ikegami Shiro , Yang Huijun , Nathanson David , Villa Genaro R. , Shackelford David , Zhu Shaojun , Tanaka Kazuhiro , Babic Ivan , Akhavan David , Lin Kelly , Assuncao Alvaro , Gu Yuchao , Bonetti Bruno , Mortensen Deborah S. , Xu Shuichan , Raymon Heather K. , Cavenee Webster K. , Furnari Frank B. , James C. David , Kroemer Guido , Heath James R. , Hege Kristen , Chopra Rajesh , Cloughesy Timothy F. , Mischel Paul S.
Published: April 2023

PDF file - 5300K, CC214-1 synergizes at low doses with rapamycin. Quantification of the blots shown in Fig. 2B. PTEN detection on DEAL captured GBM39 cells upon CC214-1 treatment.
Supplementary Table 2 from Identification of microRNA-135b in Stool as a Potential Noninvasive Biomarker for Colorectal Cancer and Adenoma
Authors: Wu Chung Wah , Ng Siew Chien , Dong Yujuan , Tian Linwei , Ng Simon Siu Man , Leung Wing Wa , Law Wai Tak , Yau Tung On , Chan Francis Ka Leung , Sung Joseph Jao Yiu , Yu Jun
Published: April 2023

PDF file - 15KB, Characteristics of CRC and advanced adenoma patients in initial microRNA profiling.
Supplementary Figure Legends from In Vivo Fluorescence Lifetime Imaging for Monitoring the Efficacy of the Cancer Treatment
Authors: Ardeshirpour Yasaman , Chernomordik Victor , Hassan Moinuddin , Zielinski Rafal , Capala Jacek , Gandjbakhche Amir
Published: April 2023

PDF file - 68KB
Supplementary Methods, Figure Legend from HIF-1α of Bone Marrow Endothelial Cells Implies Relapse and Drug Resistance in Patients with Multiple Myeloma and May Act as a Therapeutic Target
Authors: Ria Roberto , Catacchio Ivana , Berardi Simona , De Luisi Annunziata , Caivano Antonella , Piccoli Claudia , Ruggieri Vitalba , Frassanito Maria Antonia , Ribatti Domenico , Nico Beatrice , Annese Tiziana , Ruggieri Simona , Guarini Attilio , Minoia Carla , Ditonno Paolo , Angelucci Emanuele , Derudas Daniele , Moschetta Michele , Dammacco Franco , Vacca Angelo
Published: April 2023

PDF file - 156K
Supplementary Figure 2 from Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
Authors: Rao Guanhua , Wang Hongyi , Li Baowei , Huang Li , Xue Danfeng , Wang Xiaohui , Jin Haijing , Wang Jun , Zhu Yushan , Lu Youyong , Du Lei , Chen Quan
Published: April 2023

PDF file - 1365K, Co-culture of HT-29 and macrophages promotes OPN secretion in macrophages.
Supplementary Methods from DNA Methyltransferase Inhibition Reverses Epigenetically Embedded Phenotypes in Lung Cancer Preferentially Affecting Polycomb Target Genes
Authors: Hascher Antje , Haase Ann-Kristin , Hebestreit Katja , Rohde Christian , Klein Hans-Ulrich , Rius Maria , Jungen Dominik , Witten Anika , Stoll Monika , Schulze Isabell , Ogawa Seishi , Wiewrodt Rainer , Tickenbrock Lara , Berdel Wolfgang E. , Dugas Martin , Thoennissen Nils H. , Müller-Tidow Carsten
Published: April 2023

PDF file - 118K
Supplementary Table A3 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Authors: Tabernero Josep , Garcia-Carbonero Rocio , Cassidy James , Sobrero Alberto , Van Cutsem Eric , Köhne Claus-Henning , Tejpar Sabine , Gladkov Oleg , Davidenko Irina , Salazar Ramon , Vladimirova Liubov , Cheporov Sergey , Burdaeva Olga , Rivera Fernando , Samuel Leslie , Bulavina Irina , Potter Vanessa , Chang Yu-Lin , Lokker Nathalie A. , O'Dwyer Peter J.
Published: April 2023

Study drug dosing
Supplementary Table A1 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Authors: Tabernero Josep , Garcia-Carbonero Rocio , Cassidy James , Sobrero Alberto , Van Cutsem Eric , Köhne Claus-Henning , Tejpar Sabine , Gladkov Oleg , Davidenko Irina , Salazar Ramon , Vladimirova Liubov , Cheporov Sergey , Burdaeva Olga , Rivera Fernando , Samuel Leslie , Bulavina Irina , Potter Vanessa , Chang Yu-Lin , Lokker Nathalie A. , O'Dwyer Peter J.
Published: April 2023

Progression-free survival (Kaplan-Meier Method) by PIK3CA and NRAS status
Supplementary Figure 5 from Glioma Grade Is Associated with the Accumulation and Activity of Cells Bearing M2 Monocyte Markers
Authors: Prosniak Michael , Harshyne Larry A. , Andrews David W. , Kenyon Lawrence C. , Bedelbaeva Kamila , Apanasovich Tatiyana V. , Heber-Katz Ellen , Curtis Mark T. , Cotzia Paolo , Hooper D. Craig
Published: April 2023

PDF - 72K, Expression of monocyte phenotype markers and IL-10 in malignant gliomas.
Supplementary Figure 2 from Increased KIT Inhibition Enhances Therapeutic Efficacy in Gastrointestinal Stromal Tumor
Authors: Kim Teresa S. , Cavnar Michael J. , Cohen Noah A. , Sorenson Eric C. , Greer Jonathan B. , Seifert Adrian M. , Crawley Megan H. , Green Benjamin L. , Popow Rachel , Pillarsetty Nagavarakishore , Veach Darren R. , Ku Anson T. , Rossi Ferdinand , Besmer Peter , Antonescu Cristina R. , Zeng Shan , DeMatteo Ronald P.
Published: April 2023

PDF file - 35KB, Supplemental Figure S2. Biodistribution of 99mTc-Sestamibi in KitV558del/+ mice.
Supplementary Figure S6 from Expression Defect Size among Unclassified MLH1 Variants Determines Pathogenicity in Lynch Syndrome Diagnosis
Authors: Hinrichsen Inga , Brieger Angela , Trojan Jörg , Zeuzem Stefan , Nilbert Mef , Plotz Guido
Published: April 2023

PDF file - 193 KB, MutL� structure and the effects of substitutions on stability. Cartoon representation of the N- (top) and C-terminal (bottom) domains of MutL�; for better visibility, both domains are rotated against each other. MLH1 is colored cyan, PMS2 in grey. The In subdomain is highlighted blue. Bound nucleotides in the N-terminal domain are in ball-and-stick presentation, magnesium-ions are shown as orange spheres. The location of all residues whose substitutions have been investigated in this study are shown as spheres of their respective C� atoms, color-coded by the stability as determined in the experiments. A detail of a three-helix motif (helices B-C-D) of the MLH1 In subdomain is shown at the bottom.
Supplementary Figure S5 from Expression Defect Size among Unclassified MLH1 Variants Determines Pathogenicity in Lynch Syndrome Diagnosis
Authors: Hinrichsen Inga , Brieger Angela , Trojan Jörg , Zeuzem Stefan , Nilbert Mef , Plotz Guido
Published: April 2023

PDF file - 81 KB, MAPP-MMR evaluation of the investigated MLH1 variants. MAPP-MMR (Multivariate Analysis of Protein Polymorphism-Mismatch Repair) values were calculated for all variants investigated in this study. Their individual dots in the Repair-Expression diagram (Figure 1C) were colored according to the calculated values, from green (low MAPP-MMR values corresponding to a low probability of the variant being deleterious) to red (high MAPP-MMR values corresponding to a high probability of the variant being deleterious). The mean score for variants classified deleterious by the authors was 16.5, the mean score for variants with uncertain significance was 10.8, and the mean score for neutral variants was 3.5. Variants with scores from 3.0 to 5.0 are considered as "borderline".
Supplementary Figure S1 from Expression Defect Size among Unclassified MLH1 Variants Determines Pathogenicity in Lynch Syndrome Diagnosis
Authors: Hinrichsen Inga , Brieger Angela , Trojan Jörg , Zeuzem Stefan , Nilbert Mef , Plotz Guido
Published: April 2023

PDF file - 41 KB, Calibration data of the hMLH1 qPCR. Serial dilutions of a plasmid vector containing the MLH1 cDNA were produced, and aliquots of these dilutions were subject to quantitative PCR for MLH1 as detailed above. Cq values were retrieved, and linear regression was performed using the logarithmic values of the input amount of DNA and the Cq. Correlation coefficient (r) and PCR efficiency were calculated. The qPCR was linear over at least 7 orders of magnitude.
Supplementary Figure 2 from Plasma MicroRNA Are Disease Response Biomarkers in Classical Hodgkin Lymphoma
Authors: Jones Kimberley , Nourse Jamie P. , Keane Colm , Bhatnagar Atul , Gandhi Maher K.
Published: April 2023

PDF file - 51K, Figure S2. Pre-therapy versus healthy controls absolute quantification of circulating miRNA.
Supplementary Figure S8 from Targeting Small Cell Lung Cancer Harboring PIK3CA Mutation with a Selective Oral PI3K Inhibitor PF-4989216
Authors: Walls Marlena , Baxi Sangita M. , Mehta Pramod P. , Liu Kevin K.-C. , Zhu JinJiang , Estrella Heather , Li Chunze , Zientek Michael , Zong Qing , Smeal Tod , Yin Min-Jean
Published: April 2023

PDF file 69K, Supplementary Figure S8: PF-4989216 was not effective to induce anti-tumor activity in SCLC models with PTEN loss
Supplementary Figure S7 from Targeting Small Cell Lung Cancer Harboring PIK3CA Mutation with a Selective Oral PI3K Inhibitor PF-4989216
Authors: Walls Marlena , Baxi Sangita M. , Mehta Pramod P. , Liu Kevin K.-C. , Zhu JinJiang , Estrella Heather , Li Chunze , Zientek Michael , Zong Qing , Smeal Tod , Yin Min-Jean
Published: April 2023

PDF file 39K, Supplementary Figure S7: PF-4989216 was well tolerated in mice
Supplementary Table 5 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
Authors: Lleras Roberto A. , Smith Richard V. , Adrien Leslie R. , Schlecht Nicolas F. , Burk Robert D. , Harris Thomas M. , Childs Geoffrey , Prystowsky Michael B. , Belbin Thomas J.
Published: April 2023

PDF file, 1045K, Validation of hypermethylated CpG loci identified in HNSCC using TCGA data.
Supplementary Table 2 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
Authors: Lleras Roberto A. , Smith Richard V. , Adrien Leslie R. , Schlecht Nicolas F. , Burk Robert D. , Harris Thomas M. , Childs Geoffrey , Prystowsky Michael B. , Belbin Thomas J.
Published: April 2023

PDF file, 2377K, List of hypermethylated and hypomethylated CpG loci identified in OPSCC.
Supplementary Table 1 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
Authors: Lleras Roberto A. , Smith Richard V. , Adrien Leslie R. , Schlecht Nicolas F. , Burk Robert D. , Harris Thomas M. , Childs Geoffrey , Prystowsky Michael B. , Belbin Thomas J.
Published: April 2023

PDF file, 1284K, List of hypermethylated and hypomethylated CpG loci identified in OCSCC.
Supplementary Table 5 from BET Bromodomain Inhibition of MYC-Amplified Medulloblastoma
Authors: Bandopadhayay Pratiti , Bergthold Guillaume , Nguyen Brian , Schubert Simone , Gholamin Sharareh , Tang Yujie , Bolin Sara , Schumacher Steven E. , Zeid Rhamy , Masoud Sabran , Yu Furong , Vue Nujsaubnusi , Gibson William J. , Paolella Brenton R. , Mitra Siddhartha S. , Cheshier Samuel H. , Qi Jun , Liu Kun-Wei , Wechsler-Reya Robert , Weiss William A. , Swartling Fredrik J. , Kieran Mark W. , Bradner James E. , Beroukhim Rameen , Cho Yoon-Jae
Published: April 2023

PDF file - 79K, C2 Gene Sets down-regulated following treatment with JQ1.
Supplementary Table 3 from BET Bromodomain Inhibition of MYC-Amplified Medulloblastoma
Authors: Bandopadhayay Pratiti , Bergthold Guillaume , Nguyen Brian , Schubert Simone , Gholamin Sharareh , Tang Yujie , Bolin Sara , Schumacher Steven E. , Zeid Rhamy , Masoud Sabran , Yu Furong , Vue Nujsaubnusi , Gibson William J. , Paolella Brenton R. , Mitra Siddhartha S. , Cheshier Samuel H. , Qi Jun , Liu Kun-Wei , Wechsler-Reya Robert , Weiss William A. , Swartling Fredrik J. , Kieran Mark W. , Bradner James E. , Beroukhim Rameen , Cho Yoon-Jae
Published: April 2023

PDF file - 63K, MYC gene sets enriched in medulloblastoma samples with high expression of MYC isoforms.
Supplementary Figure 1 from Tumor Genetic Analyses of Patients with Metastatic Melanoma Treated with the BRAF Inhibitor Dabrafenib (GSK2118436)
Authors: Nathanson Katherine L. , Martin Anne-Marie , Wubbenhorst Bradley , Greshock Joel , Letrero Richard , D'Andrea Kurt , O'Day Steven , Infante Jeffrey R. , Falchook Gerald S. , Arkenau Hendrik-Tobias , Millward Michael , Brown Michael P. , Pavlick Anna , Davies Michael A. , Ma Bo , Gagnon Robert , Curtis Martin , Lebowitz Peter F. , Kefford Richard , Long Georgina V.
Published: April 2023

Supplementary Figure 1 - PDF file 214K, Copy number in baseline samples from patients with partial response compared to those with stable or progressive disease
Supplementary Figure 1 from BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
Authors: Frederick Dennie T. , Piris Adriano , Cogdill Alexandria P. , Cooper Zachary A. , Lezcano Cecilia , Ferrone Cristina R. , Mitra Devarati , Boni Andrea , Newton Lindsay P. , Liu Chengwen , Peng Weiyi , Sullivan Ryan J. , Lawrence Donald P. , Hodi F. Stephen , Overwijk Willem W. , Lizée Gregory , Murphy George F. , Hwu Patrick , Flaherty Keith T. , Fisher David E. , Wargo Jennifer A.
Published: April 2023

PDF file - 112K, Inhibition of BRAFV600E increases expression of MART-1 in tumors of patients with metastatic melanoma.
Supplementary Figure 4 from MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer
Authors: Yu San-Jian , Hu Jing-Ying , Kuang Xia-Ying , Luo Jian-Min , Hou Yi-Feng , Di Gen-Hong , Wu Jiong , Shen Zhen-Zhou , Song Hou-Yan , Shao Zhi-Ming
Published: April 2023

PDF file - 277K, In vivo lung metastases induced by breast cancer cells
Supplementary Table S3 from T-cell Responses to Oncogenic Merkel Cell Polyomavirus Proteins Distinguish Patients with Merkel Cell Carcinoma from Healthy Donors
Authors: Lyngaa Rikke , Pedersen Natasja Wulff , Schrama David , Thrue Charlotte Albæk , Ibrani Dafina , Met Özcan , thor Straten Per , Nghiem Paul , Becker Jürgen C. , Hadrup Sine Reker
Published: April 2023

XLSX file 22K, Selected peptides
Supplementary Figure 8 from An Unconventional KITENIN/ErbB4-Mediated Downstream Signal of EGF Upregulates c-Jun and the Invasiveness of Colorectal Cancer Cells
Authors: Bae Jeong A. , Yoon Somy , Park So-Yeon , Lee Jae Hyuk , Hwang Jun-Eul , Kim Hangun , Seo Young-Woo , Cha Yoon Jin , Hong Sung Pil , Kim Hoguen , Chung Ik Joo , Kim Kyung Keun
Published: April 2023

PDF file - 662K, Figure 8. Higher expression levels of KITENIN affect the survival of CRC cells to the anti-proliferative effects of cetuximab.
Supplementary Figure S2 from T-cell Responses to Oncogenic Merkel Cell Polyomavirus Proteins Distinguish Patients with Merkel Cell Carcinoma from Healthy Donors
Authors: Lyngaa Rikke , Pedersen Natasja Wulff , Schrama David , Thrue Charlotte Albæk , Ibrani Dafina , Met Özcan , thor Straten Per , Nghiem Paul , Becker Jürgen C. , Hadrup Sine Reker
Published: April 2023

PDF file 56K, Flow cytrometry dot plot
Supplementary Figure 3 from An Unconventional KITENIN/ErbB4-Mediated Downstream Signal of EGF Upregulates c-Jun and the Invasiveness of Colorectal Cancer Cells
Authors: Bae Jeong A. , Yoon Somy , Park So-Yeon , Lee Jae Hyuk , Hwang Jun-Eul , Kim Hangun , Seo Young-Woo , Cha Yoon Jin , Hong Sung Pil , Kim Hoguen , Chung Ik Joo , Kim Kyung Keun
Published: April 2023

PDF file - 135K, Figure 3. EGF-induced AP-1 synergy under elevated KITENIN conditions does not require activated JNK.
Supplementary Figure 1 from An Unconventional KITENIN/ErbB4-Mediated Downstream Signal of EGF Upregulates c-Jun and the Invasiveness of Colorectal Cancer Cells
Authors: Bae Jeong A. , Yoon Somy , Park So-Yeon , Lee Jae Hyuk , Hwang Jun-Eul , Kim Hangun , Seo Young-Woo , Cha Yoon Jin , Hong Sung Pil , Kim Hoguen , Chung Ik Joo , Kim Kyung Keun
Published: April 2023

PDF file - 126K, Figure 1. EGF induces synergic AP-1 activation under elevated KITENIN in an EGFR- and EGFR-kinase-independent manner.
Supplementary Table S3 from Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors
Authors: Vrignaud Patricia , Sémiond Dorothée , Lejeune Pascale , Bouchard Hervé , Calvet Loreley , Combeau Cecile , Riou Jean-François , Commerçon Alain , Lavelle François , Bissery Marie-Christine
Published: April 2023

Supplementary Table S3 - PDF file 53K, Schedule of cabazitaxel administration in non-tumor-bearing B6D2F1 female mice
Supplementary Figure 1 from Mechanisms of Activity of the TORC1 Inhibitor Everolimus in Waldenstrom Macroglobulinemia
Authors: Roccaro Aldo M. , Sacco Antonio , Jia Xiaojing , Banwait Ranjit , Maiso Patricia , Azab Feda , Flores Ludmila , Manier Salomon , Azab Abdel Kareem , Ghobrial Irene M.
Published: April 2023

PDF file - 32K, Everolimus targets mTOR-down stream targets in WM patients. Bone marrow specimens have been stained for phosphor(p)-S6R and p-4EBP1. Signal quantification for each target has been obtained from 4 different areas, on matched pre- and post-everolimus treatment of 4 patients presenting with partial response; and on matched pre- and post-everolimus treatment of 3 patients presenting with stable disease. Number of positive cells has been obtained on 4 different fields of the bone marrow biopsy, and average and standard deviation provided. P indicates P values; N.S.: not significant.
Supplementary Figure 1 from A Phase I Trial of Dasatinib, an Src-Family Kinase Inhibitor, in Combination with Paclitaxel and Carboplatin in Patients with Advanced or Recurrent Ovarian Cancer
Authors: Secord Angeles Alvarez , Teoh Deanna K. , Barry William T. , Yu Miao , Broadwater Gloria , Havrilesky Laura J. , Lee Paula S. , Berchuck Andrew , Lancaster Johnathan , Wenham Robert M.
Published: April 2023

PDF file, 92K, Volcano Plot.
Supplementary Methods from First-in-Human, Phase I Dose-Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of RO5126766, a First-in-Class Dual MEK/RAF Inhibitor in Patients with Solid Tumors
Authors: Martinez-Garcia Maria , Banerji Udai , Albanell Joan , Bahleda Rastilav , Dolly Saoirse , Kraeber-Bodéré Françoise , Rojo Federico , Routier Emilie , Guarin Ernesto , Xu Zhi-Xin , Rueger Ruediger , Tessier Jean J. L. , Shochat Eliezer , Blotner Steve , Naegelen Valerie Meresse , Soria Jean-Charles
Published: April 2023

PDF file, 130K.
Supplementary Figure Legend from Enhancement of Human Cancer Cell Motility and Invasiveness by Anaphylatoxin C5a via Aberrantly Expressed C5a Receptor (CD88)
Authors: Nitta Hidetoshi , Wada Yoshihiro , Kawano Yoshiaki , Murakami Yoji , Irie Atsushi , Taniguchi Keisuke , Kikuchi Ken , Yamada Gen , Suzuki Kentaro , Honda Jiro , Wilson-Morifuji Masayo , Araki Norie , Eto Masatoshi , Baba Hideo , Imamura Takahisa
Published: April 2023

PDF file - 108K
Supplementary Table 1 from Functional Identification of Cancer-Specific Methylation of CDO1, HOXA9, and TAC1 for the Diagnosis of Lung Cancer
Authors: Wrangle John , Machida Emi Ota , Danilova Ludmila , Hulbert Alicia , Franco Noreli , Zhang Wei , Glöckner Sabine C. , Tessema Mathewos , Van Neste Leander , Easwaran Hariharan , Schuebel Kornel E. , Licchesi Julien , Hooker Craig M. , Ahuja Nita , Amano Jun , Belinsky Steven A. , Baylin Stephen B. , Herman James G. , Brock Malcolm V.
Published: April 2023

XLSX file - 25KB, List of Infinium 450K Methylation Probes from Figure 1.
Supplementary Table 1 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer
Authors: Tian Junqiang , Zhao Hongjuan , Nolley Rosalie , Reese Stephen W. , Young Sarah R. , Li Xuejun , Peehl Donna M. , Knox Susan J.
Published: April 2023

XLS file, 83KB.
Supplementary Table 1 from miR-187 Is an Independent Prognostic Factor in Breast Cancer and Confers Increased Invasive Potential In Vitro
Authors: Mulrane Laoighse , Madden Stephen F. , Brennan Donal J. , Gremel Gabriela , McGee Sharon F. , McNally Sara , Martin Finian , Crown John P. , Jirström Karin , Higgins Desmond G. , Gallagher William M. , O'Connor Darran P.
Published: April 2023

PDF file - 68K, Clinicopathological charactistics of tumours in Cohorts 1 and 2
Supplementary Figure 5 from miR-187 Is an Independent Prognostic Factor in Breast Cancer and Confers Increased Invasive Potential In Vitro
Authors: Mulrane Laoighse , Madden Stephen F. , Brennan Donal J. , Gremel Gabriela , McGee Sharon F. , McNally Sara , Martin Finian , Crown John P. , Jirström Karin , Higgins Desmond G. , Gallagher William M. , O'Connor Darran P.
Published: April 2023

PDF file - 47K, miR187 expression and patient outcome stratified according to ER status
Supplementary Figure 3 from A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB
Authors: Gopalakrishnan Ramakrishnan , Matta Hittu , Chaudhary Preet M.
Published: April 2023

PDF file, 2386K, The effect of BIIB021 on the mRNA transcript of various KSHV genes were given in this file.
Supplementary Figure Legends from Combined Targeting of STAT3/NF-κB/COX-2/EP4 for Effective Management of Pancreatic Cancer
Authors: Gong Jingjing , Xie Jianping , Bedolla Roble , Rivas Paul , Chakravarthy Divya , Freeman James W. , Reddick Robert , Kopetz Scott , Peterson Amanda , Wang Huamin , Fischer Susan M. , Kumar Addanki P.
Published: April 2023

PDF file - 95KB
Supplementary Figure 1 from A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB
Authors: Gopalakrishnan Ramakrishnan , Matta Hittu , Chaudhary Preet M.
Published: April 2023

PDF file, 3187K, The densitometric analysis of blots from figure 4B is given in this file.
Supplementary Figure 8 from Contribution of OATP1B1 and OATP1B3 to the Disposition of Sorafenib and Sorafenib-Glucuronide
Authors: Zimmerman Eric I. , Hu Shuiying , Roberts Justin L. , Gibson Alice A. , Orwick Shelley J. , Li Lie , Sparreboom Alex , Baker Sharyn D.
Published: April 2023

PDF file - 62K, Influence of Oatp1a/b-deficiency on sorafenib metabolism ex vivo.
Supplementary Figure 5 from Contribution of OATP1B1 and OATP1B3 to the Disposition of Sorafenib and Sorafenib-Glucuronide
Authors: Zimmerman Eric I. , Hu Shuiying , Roberts Justin L. , Gibson Alice A. , Orwick Shelley J. , Li Lie , Sparreboom Alex , Baker Sharyn D.
Published: April 2023

PDF file - 345K, Influence of Oatp1b2-deficiency on the liver-to-plasma ratio of sorafenib, sorafenib N-oxide, and sorafenib-glucuronide in vivo.
Supplementary Tables 1 - 9, Figures 1 - 5 from The Impact of EGFR T790M Mutations and BIM mRNA Expression on Outcome in Patients with EGFR-Mutant NSCLC Treated with Erlotinib or Chemotherapy in the Randomized Phase III EURTAC Trial
Authors: Costa Carlota , Molina Miguel Angel , Drozdowskyj Ana , Giménez-Capitán Ana , Bertran-Alamillo Jordi , Karachaliou Niki , Gervais Radj , Massuti Bartomeu , Wei Jia , Moran Teresa , Majem Margarita , Felip Enriqueta , Carcereny Enric , Garcia-Campelo Rosario , Viteri Santiago , Taron Miquel , Ono Mayumi , Giannikopoulos Petros , Bivona Trever , Rosell Rafael
Published: April 2023

PDF file - 934K, Table S1. Quantification of T790M allele in our samples Table S2. Percentage of EGFR T790M mutation in each sample. Table S3. Results of the analysis of the T790M mutation in 705 paraffin-embedded lung tumor samples using our PNA method. Table S4. Primers for TP53 genotyping. Table S5. Cell lines used as controls for TP53 genotyping Table S6. Annealing conditions for TP53 genotyping. Table S7. Comparison of studies detecting the T790M mutation by different methods. Table S8. Summary of all systemic treatments after discontinuation of randomly assigned treatment in 95 patients included in the EURTAC study. Table S9. Response according to T790M status in both arms. Figure S1. Representation of deltaCt (mean) versus the ratio of the T790M allele in our in-house assay in (A, B) two separate dilution banks where the total amount of mutated DNA was 50 pg/microL and (C) in a dilution bank where the total amount of mutated DNA was 5 pg/microL. Figure S2. Progression-free survival according to T790M mutation status in (S1A) 50 patients treated with erlotinib and (S1B) 45 patients treated with chemotherapy. Figure S3. Progression-free survival according to T790M mutation status as determined by the TMDA in the entire cohort of 95 patients. Figure S4. Overall survival of 173 patients in the EURTAC trial at January 24, 2013. Figure S5. Overall survival of 83 patients with BIM expression data according to treatment arm and BIM mRNA expression levels.
Supplementary Methods from miRNA Biomarkers in Cyst Fluid Augment the Diagnosis and Management of Pancreatic Cysts
Authors: Matthaei Hanno , Wylie Dennis , Lloyd Maura B. , Dal Molin Marco , Kemppainen Jon , Mayo Skye C. , Wolfgang Christopher L. , Schulick Richard D. , Langfield Laura , Andruss Bernard F. , Adai Alex T. , Hruban Ralph H. , Szafranska-Schwarzbach Anna E. , Maitra Anirban
Published: April 2023

PDF file, 161K.