bluuebunny/crossref_metadata_2025 huggingface dataset:
Cuckoo Search Algorithm: Review and its Application
Authors: Manar Abdulkareem Al-Abaji
Published: December 2022

Optimization techniques play a major role in real-world problems, As many cases in which decisions are made are based on random research. But choosing the optimization technology is a big challenge for the user. The cuckoo search algorithm is one of the modern optimization techniques that can replace many of the traditional techniques used, The cuckoo bird use a Levi's flight strategy based on the egg laying method to extract a solution to the problem. The presented work will provide a review of the original cuckoo search algorithm with mentioning some types of developed and hybrid cuckoo search algorithm as well as some of their applications.
Study the effect of compound Extracted from pomegranate peels and green tea on some biochemical variables in rabbit serum induced with Myocardial Infarction
Authors: Dhamyaa Wajih Yaqoup  , Nadia Ahmed Salih
Published: December 2022

This study aims to investigate the effect of compounds extracted from pomegranate peels and green tea on some biochemical variables in the serum of domestic male rabbits with recently myocardial infarction.
The study was conducted in the Animal House of the College of Veterinary Medicine. 24 male rabbits were used, with an average of weights ranging between 1800 - 2000 grams, which were divided into three groups (8 / group). The first group was fed a standard diet as a control group and the second and third group fed a standard diet added to it Cholesterol by 1%. After 45 days, the second and third group animals were dosed, in which the myocardial infarction developed the extracted compounds, and the myeloperoxidase enzyme activity and the level of troponin, potassium, and magnesium were measured.
Blood samples were collected from the control groups, the second and the third in which the disease was developed, and after 21 days the samples were collected from the second and third groups after treatment with the extracted compounds. The induction of myocardial infarction led to a significant increase in the activity of myeloperoxidase enzyme MPO and the level of troponin, potassium and magnesium, with a probability level of p≤0.01.
In comparison with control, there was a significant decrease in myeloperoxidase activity and potassium troponin level for groups in which the extracted compounds were dosed after disease onset, and with a probability p≤0.01 compared to the affected groups
Suitability of Gypsum from Fatha Formation for Production of Building Materials in Bazian -Takiya area, North-East Iraq
Authors: Chro, M. Fatah  , Jamila, J. Tahir
Published: December 2022

Gypsum products are one of the most widely used materials in the industry. The wide use of gypsum as a building material over a very long period of time. A number of manufacturers introduce different professional quarries, but their physical and chemical properties were still questionable. Five gypsum samples were taken for chemical and physical analysis. Chemical analysis shows that gypsum are of high purity, more than 95.25% with varying amount of impurities; SiO2 (1.49-1.87) %, Na2O (0.17-1.00) %, MgO (0.03-0.13) % Al2O3 (0.06-0.23) % and Fe2O3 (0.05-0.09) %, .This can be used for Plaster of Paris without any purification of gypsum. The (SO3 and CaO) % shows that all studied samples are suitable for gypsum production as the final coating and building gypsum. The physical analysis shows that the colors of gypsum samples are suitable for building, Plaster of Paris, final coating and Juss according to the color chart of minerals and to Iraqi standard specification. The fineness percentage is less than 8%. Thus the specifications of all samples are agreements to standard specifications for building gypsums. In terms of setting time, the sample 1 and 2 are suitable for building gypsum and plaster of Paris and classified as Borax. However, samples 3, 4, and 5 are suitable for anhydrous calcined gypsum – final coat and classified as Knee cement. Moreover, the setting time for all the samples increased with the increase of the water powder ratio.
Study of Rutile TiO2 band structures and optical properties using Density functional theory (DFT)
Authors: Rafea A. Munef  , Abdulhadi M. Ghaleb  , Ahmed Th. Shihatha
Published: December 2022

In this article, a theoretical analysis to measure the band composition, optical properties and density of states (DOS) of rutile titanium dioxide was conducted via the castep simulation program. Calculations of the first principles were carried out using the super cell (1x1x1) process. The first computation of  concepts was studied by density functional theory (DFT) with a generalized gradient approximation from Perdew-Wang's 1991 (GGA-PW91), local density approximation (LDA) for exchange-correlation energy functional, and (LDA)+U method, implementation of coulomb interactions btween   of ( ) atom  and  of (  ) atom.All experimental values are agreed with our results. The results for LDA and GGA-Pw91 indicated weaknesses in the estimation and far from the experimental results for the properties of the  rutile under analysis, except for the energy band difference, although the estimation data (LDA) + U was in accordance with the experimental values. The optical properties of rutile  was obtained using several methods of exchange correlations, well in accordance with experimental findings and other theoretical evidence.
Optical Properties of Iron Oxide Thin Films Prepared by Pulsed Laser Ablation Method
Authors: Rasha Hamid Ahmed
Published: December 2022

Iron oxide nanoparticles (Fe2O3) were prepared by pulsed Nd-YAG laser ablation technology for a target of iron oxide in ultra-pure water with a constant number of pulses (250) with different ablation energies (400, 500, 600, 700 and 800) mJ and formed a colloidal solution for each energy. Optical properties were calculated and changing the energy value on the preparation of iron nanoparticles was shown, and the value of energy gap varies from (2.88-3.04) eV according to the change in the ablation energy.
TEACHING STUDENTS VETERINARY TERMINOLOGY (ON THE BASIS OF THE DISEASES OF ANIMALS)
Authors: Cherepovska Tetiana , Shutak Olesia
Published: December 2022

The article is devoted to teaching English at higher veterinary institutions. The importance of mastering veterinary terminology by future specialists for the successful scientific and practical clinical activity is emphasized. The significance of understanding the main peculiarities of the veterinary terminological system is stated. The research outlines the main features of veterinary terms. It represents the classification of the names of animal diseases as a part of specific veterinary terminology. They are classified according to the key words contained in the name: the distinctive symptom stated, the afflicted organ or the susceptible animal mentioned, the name of the researcher or the place of disease outbreak denoted, etc. The importance of understanding the main morphological features of the words of Greek and Latin origin naming the diseases of animals for those enriching professional vocabulary is shown. English for veterinary students is viewed as a part of English for Specific Purposes and as the one that corresponds to its main requirements and principles. The article comprises exercises for mastering veterinary terminology denoting diseases of animals in different types of reading, speaking, listening and writing activities. The importance of using modern comprehensive and translator dictionaries by students studying veterinary terminology is emphasized. The role of co-relation with other university courses is stated and illustrated.
SEMANTICS OF THE INSPIRATIONAL SPEECHES AND THEIR COMMUNICATIVE AND PRAGMATIC POTENTIAL (A CASE STUDY OF PRINCE HARRY’S SPEECHES AT THE INVICTUS GAMES)
Authors: Odarchuk Nataliia , Mironchuk Tetiana
Published: December 2022

The article analyzes the speeches delivered by the British Prince Harry at the opening and closing ceremonies of the Invictus Games and proves their inspirational nature. Inspirational speeches are defined as a public speech aimed, as a rule, at a group of people in order to convey a strong sense of enthusiasm, to inspire and motivate them, to encourage them to take desired actions. As a result of the lexicographic analysis, the framework of the concept of to inspire was formed, the semantics of which is filled with the following semes: to encourage someone to actions, to give desire and inspiration, to fill with enthusiasm, to excite liveliness and endurance, to motivate for changes for the better, to add confidence and strength. The participants of the communicative act triad are determined: the sender – the text – the addressee/ recipient, and their roles are outlined. The sender is proved to achieve a pragmatic effect by means of the text, i.e. inspirational speeches, exerting a speech influence on the recipient. The functions of the researched speeches are formulated, which coincide with the functions of communication – informative, social, expressive, pragmatic, and interpretive. Examples are employed to illustrate the secondary nature of informative and interpretive functions and the vividness of social, expressive and pragmatic functions. Due to the presence of the inspiration pragmatics in the basis of all communicative attitudes of the researched speeches the inspirational function is singled out, which is dominant.
EPISTEMICITY OF WORDS DENOTING CERTAINTY / UNCERTAINTY
Authors: Nizhnik Lyudmila
Published: December 2022

The article explores epistemic nouns, verbs, adjectives and adverbs that convey different levels of confidence/uncertainty. The material of the study was a selection of fiction texts of modern English literature for 1 million words. The epistemic nature of words used to indicate certainty / uncertainty is studied. Epistemicity is defined as the property of words to manifest epistemic properties and is calculated as the ratio of the number of epistemic words (EW) to the total number of words for indicating certainty / uncertainty in the selection according to the formula Eep÷Et*100%, where Eep is the number of epistemic uses of the word, Et is the total number of uses of this word in the selection. The place of EWs in utterances was considered and EWs were separated from non-epistemic ones. Epistemic verbs, adjectives, and nouns occur in affirmative, negative, and interrogative object-determining utterances before the subordinate part of the statement. Epistemic verbs in interjections and epistemic adverbs occur in any part of the utterance, marking it epistemically. EW are not considered in the past and future tenses and in phrases with personal pronouns other than I, we in positive utterances and you in questions. We also study epistemic adjectives and nouns in impersonal expressions. EW cannot be adjectives of adjacent words, discursive markers, and adverbs of action. The analysis of 28 epistemic verbs showed that for verbs, epistemicity ranges from 0‒95%, and the most used epistemic verbs are think, seem, know, see. For 21 epistemic adjectives, epistemicity ranges from 0‒75%, and the most used epistemic adjectives are sure, impossible / not possible, certain, possible. Adverbs show the highest level of epistemicity (50‒100%), and among the 25 epistemic adverbs maybe, really, probably, kind of, sort of, perhaps are used most often. Nouns show the lowest epistemicity in the range of 0‒50%, and among 17 epistemic nouns, fact, feeling, doubt, idea, chance are most often used.
NON-VIOLENT UKRAINISATION: MODERN FREEDOM WEARS YELLOW-AND-BLUE
Authors: Dunaievska Olha , Stupenko Maria , Levchenko Zinayida
Published: December 2022

The paper addresses the issue of frame analysis of discourse fragments related to the high-scale war in Ukraine started by russian federation on the 24th of February 2022. The article outlines the peculiarities of Ukraine/Ukraine-related mentions in English-speaking media online discourse, the presence and accumulation of which, gives the grounds for them to be united under the notion of UKRAINISATION. The work prioritised 1) the collection of the corpus of Ukraine-connected mentions in the online available English-speaking media; 2) the selection and analysis of the basic schemas of evoked as well as invoked frames; and 3) the description of the current frames connected with Ukraine and Ukrainians. The elements of frame analyses in terms of onomasiological and semasiological approaches were used to identify the basic frame serving as a construct of the information that pertains to a particular event or a notion associated with Ukraine and Ukrainians worldwide. The corpus of the discourse fragments was retrieved from online English-speaking media; it underwent the sorting out based on the aspect its constituents appeal to. Such aspects as: expressing admiration, support (both verbally and non-verbally), showing solidarity, demonstrating sharing of same values, seeing and understanding of russian war in Ukraine. In the paper the model of non-violent Ukrainisation is offered, which supports the idea that Ukrainisation has become an embodiment of supporting modern democratic values shared by democratic societies.
SYSTEMATIC AND STRUCTURAL ORGANIZATION OF LANGUAGE
Authors: Borzenko Oleksandra
Published: December 2022

The article examines the main questions about language: essence, nature, formation, structure, mutual connection of language and thinking, relation between language and speech. It is noted that in the process of speech, a person communicates with the help of language, as the most perfect means of communication, through which the world is known, that language is a mirror of national culture, therefore its national and cultural semantics is so important, which reflects the characteristic features of the nation, its folklore, personalities of everyday life, customs and history. It was determined that during the interaction of language and speech, a constant process of appearance and formation of phraseological units is formed, which diversify, enrich speech and are a key means of further knowledge of the language, as well as important in the development of its systematic and structural organization. It is noted that the lexical-semantic system is the most mobile among all language levels. The analysis of a significant amount of scientific material on the research problem made it possible to characterize the views of scientists who are trying to identify the relations between speech categories, language elements, as well as how the systematic and structural organization of the language provides it with reproducibility, stability, the ability for constant development and universalism. The universality of language enables a person to use it as a means of communication in all communication situations, including with other cultures. The universality of language directly enables both internal and intercultural communication. It was determined that language is much more complex than the systems offered by linguists and is the most complex multidimensional entity that is formed in the human mind as a result of acquiring social experience.
THE COLOR IDIOMS IN THE LINGUISTIC AND CULTURAL UNDERSTANDING OF THE IMPLICIT MEANING IN ENGLISH AND UKRAINIAN LANGUAGES
Authors: Novoseletska Svitlana V. , Ivchenko-Chekholka Yuliia
Published: December 2022

The article examines the problem of using the complete idioms with colors in English and Ukrainian. The article covers the definition of idioms and various approaches to their study and use by famous linguists. The authors present a classification of idioms, in particular semantic and structural. In addition, the syntactic study of constituents consisting of color idioms is considered. The researching discusses the implicit nature of color idioms in English and Ukrainian. The term "implicit meaning" is considered as the meaning that may not be obvious to speakers of foreign languages. The research work mainly analyzes common color idioms found in English and Ukrainian languages, as well as those idioms that have no semantic or structural equivalents in the compared languages. The relevance of this work lies in the fact that today's realities, the global interrelationships of nations and the cultural varieties of our planet in the 21st century, the growing needs for communication and work between countries and people of different languages ​​and cultural traditions require the training of highly qualified teachers who are able to participate in international communication and international cooperation and the formation of a new attitude towards Ukraine in Europe and around the world. That is why today the research and use of the linguistic phenomenon associated with color idioms is considered as one of the problems that is in the center of attention of linguists all over the world.
EMOTIONAL COLOURING OF HORROR LITERATURE: TRANSLATIONAL ASPECT
Authors: Ivanova Andriana , Hliudzyk Yuliia
Published: December 2022

The article elucidates the emotivity of horror literature in the light of translation studies. Based upon the classical material of the research the specificity of emotions’ verbalization has been discussed. The dominant negative emotions such as agony, fierce, anger, hatred are depicted jointly and tightly. A prominent emotive feature of the horror genre is emotions’ depiction on physiological processes. It allows describing hero’s emotional worries through the prism of inner changes in his/her state of health and body in general. The article touches upon the most vivid descriptions of physiological changes depicting emotions and emotive sketches with somatisms blood and heart. Horror genre texts are full of emotive paragraphs and reveal the inner world oh heroes’ emotions. Emotions in horror literature are depicted by means of nomination and contextual description with the help of lexical and linguostylistic means. Preserving the emotive component in the target text is a complex and crucial task for a translator. Rendering emotivity without overinterpretation of the source text and without imposing one’s personal emotional world requires a high level of professionalism. Translators rendering the negative palette of emotions face stylistic omissions and neutralizations that results in the low level of emotivity in the target text. Alongside, stylistic equivalents are also present the target texts that proves the translators’ willingness and desire to be close to the author of the original. Emotional tension and suspense that are also considered necessary to be saved in the target text are preserved by the translators using stylistic intensification and equivalents.
AUTHENTIC MATERIALS AS A MEANS OF CULTURAL COMPETENCE DEVELOPMENT OF STUDENTS
Authors: Lutai Natalia , Besarb Tetyna
Published: December 2022

This article is devoted to the problem of formation of students’ cultural competence. The authors consider the study of English through the prism of cultural competence, since the study of language and culture are closely related to each other. The paper also describes a few techniques which encourage the development of intercultural competence proposed in some studies, in particular, the comparative approach. Special attention is paid to possible ways of motivating students with different backgrounds and levels of knowledge to integrate into a cohesive and productive classroom, as well as the importance of theory of collaborative learning is noted. What’s more, some causes which can seriously affect students’ speech are described, e.g. indifference of their interlocutors, no matter, it is real or perceived. On the other hand, as long as students are supposed to speak openly, they are prone to expressing their thoughts more freely, what makes it easier for them to overcome shyness, which contributes to a more free assimilation of the language. Teachers can encourage students to participate in authentic personally meaningful, language learning sessions in case they allow learners to suggest topics for discussions, choose materials, and present these issues in class. Teaching students to share their points of view, lecturers promote a socially and culturally engaged autonomy.When a contemporary social and cultural context are provided, students have the opportunity to control and assess their own learning process and become a part of the language community. In addition, the article presents various options for using authentic materials in the classroom.
DEVELOPING INTERCULTURAL COMPETENCE OF FUTURE NAVIGATORS AS A BACKGROUND OF EFFECTIVE INTERCULTURAL COMMUNICATION
Authors: Didenko Maria
Published: December 2022

The article aims to study the resources that can be used by foreign language teachers of universities to achieve standards of higher education and the development of intercultural competence as an integral part of the professional education of modern experts and background for effective intercultural communication. This leads to the importance of developing respect for other cultures, tolerance, empathy, desire to learn about foreign cultures, etc. And thus, it enables the development of a global expert who easily adapts to the modern requirements of society in an intercultural environment. The article analyses relevant scientific papers and the requirements for modern experts in the development of intercultural competence. This makes it possible to say that an important task of teaching intercultural competence is to develop students’ ability to participate in intercultural dialogue, taking into account the principles of cooperation and mutual respect, forming a sense of belonging to their own culture. Based on the theory of high-context and low-context cultures, the authors made a comparative description of the representatives of Ukrainian, Philipino, Indian and Greek cultures, because Ukrainian sailors work mostly in this international crew. The features of the cultures presented in the table make it easier to adapt to the intercultural environment and understand and tolerate intercultural differences. The article offers practical assignments for the development of intercultural competence at foreign language classes in higher education institutions, including maritime English.
The Idea of “Proactive Library” in R.A. Baryshev’s Monograph and Dissertation as Manifestation of Dilettantism
Authors: Stolyarov Yury N.
Published: December 2022

The monograph “Proactive library in the information and educational environment of University” (2020) and the dissertation for the degree of Doctor of Pedagogical Sciences “University library as a proactive system: modern opportunities and development prospects” (2022; rejected by the Dissertation Council upon the results of defense) by R.A. Baryshev use methodologically flawed basis and theoretically are untenable. The monograph and dissertation on the so-called proactive university library as a system do not contain scientific novelty and of no practical value.

The main idea of the “proactive library” is to focus on anticipating readers’ requests and, therefore, it requires reliance on forecasting methodology. However, the author of the monograph and dissertation presents other methodological grounds. The conceptual grounds that should form the essence of the theoretical development of the topic raised and should have theoretical novelty and scientific significance, in fact, are reduced to principles that have long been known and widely used in practice, and the key strategic directions that complement them, as the author himself notes, have been developed by an external institution. R.A. Baryshev did not show how the library services offered by him work ahead of requests. The monograph and dissertation do not contain information on what was exactly provided for in advance and what is the proportion of justified forecasts. The monograph was released without scientific review; it does not make any significant contribution to the library theory and practice. The main text is prepared on the materials of only one library — the Siberian Federal University, it has no grounds to claim generalizations that apply to all university libraries of the country. At the same time, the stated topic — forecasting of readers’ needs and requests and their preventive satisfaction — is of exceptional importance for library science and it requires qualified research.
Distributions of Phytophagous Syrphidae (Diptera) Species of the Lakes Region of Turkey
Authors: UZUN YİĞİT Asiye , DEMİRÖZER Ozan , HAYAT Rüstem , VUJIC Ante
Published: December 2022

This study was carried out by visiting the designated areas at least twice between the months of April and October of each year between 2014 and 2016 to determine the phytophagous Syrphidae species in Antalya (Korkuteli), Afyonkarahisar (Dazkırı, Dinar), Burdur, Isparta (all districts), and Konya (Beyşehir) located within the borders of the Lakes Region. Adult syrphid individuals were collected from trees, shrubs, and herbaceous plants using sweep-net and mouth aspirator from agricultural areas, uncultivated lands and forest areas rich in vegetation and flowering plants in 46 different sampling points. As a result of the study, a total of 48 phytophagous species belonging to the genera Cheilosia (7), Eumerus (13) and Merodon (28) were found. Merodon nigritarsis (17 %), Merodon aff. bessarabicus (8 %), Merodon spinitarsis (6,25 %), Eumerus bicornis (6,16 %), Merodon crassifemoris (6,16 %) Merodon italicus (5,5 %), Merodon avidus (5 %), Cheilosia soror (3.2 %) and Merodon alagoezicus (2,6 %) were determined as the most abundant and common species.
Vinculación con la sociedad: fortalecimiento de procesos comunicacionales desde la academia, año 2019
Authors: Vélez Bermello Gabriela Lourdes , González Santos Milton Marco , Lindao Lindao Ulises Sebastián , Yagual Panimboza Ariana Anais
Published: December 2022

Un aspecto relevante en la vinculación con la sociedad es obtener resultados pro-positivos a través de losprocesos entre beneficiarios, estudiantes y docentes. Este estudio devela los conocimientos adquiridos por los participantes de un proyecto de vinculación en la carrera de Comunicación de la Universidad Estatal Península de Santa Elena. El objetivo fue analizar cómo los beneficiarios aprovecharon los conocimientos generando en conjunto con los estudiantes, insumos comunicacionales que coadyuvan a la potencialización del sector turístico. Se aplicó una metodología descriptiva de carácter cuali-cuantitativo, con la que se generaron grupos focales y encuestas a todos los colaboradores antes, durante y después del proceso. Este estudio demuestra desde el punto de vista de los beneficiarios, que no solo se necesita un capital económico para emprender un negocio sino conocimientos básicos en procesos comunicacionales; mientras que en el personal universitario se evidenció lo fundamental de integrar acciones para contribuir a las mejoras sociales.
Educar el ocio en la sociedad apresurada: El Ocio Valioso como horizonte
Authors: Martínez García Rubén , Caballo Villar Mª Belén
Published: December 2022

Partiendo del conflicto de los tiempos sociales que caracteriza la actual sociedad red, en el presente trabajo se destaca la necesidad de repensar su organización y potenciar un mayor protagonismo de los tiempos de ocio, pues constituyen un referente para el desarrollo humano. Así, por medio de una fundamentada reflexión teórica, y justificada la importancia del ocio como tiempo con valor en sí mismo, el artículo tiene un doble objetivo: analizar las principales teorías que explican los diferentes grados de intensidad de la experiencia de ocio y su distinta influencia en el desarrollo humano, así como la importancia que tiene la educación del ocio en la conquista de aquellas experiencias más intensas y, por tanto, valiosas que son las que ofrecen mayores cotas de bienestar. Se concluye poniendo en valor la necesidad de plantear políticas públicas sobre los usos sociales del tiempo, que permitan armonizarlos a fin de que la ciudadanía encuentre en el ocio un ámbito de desarrollo y crecimiento personal.
La enseñanza problemática en la universidad médica
Authors: Quiroga Torres Tannia Elizabeth , Hernández Navarro Elena Vicenta , Delgado López Verónica Carlina , Villacis Valencia Sandra
Published: December 2022

La enseñanza problémica es la participación independiente y proactiva de los estudiantes, para solucionar problemas reales a través de la integración del saber ser, saber –saber y saber hacer, alcanzando un aprendizaje por competencias, acorde a las demandas del mundo actual. El objetivo del artículo fue exponer la importancia de aplicar la enseñanza problémica mediante el análisis de referentes didácticos, para lograr una educación de calidad en las universidades médicas. Se realizó una revisión bibliográfica de 30 artículos publicados en diferentes bases de datos. Concluyendo que, para las instituciones encargadas de la formación médica, es necesario la adopción de una estructura curricular, que permita ofrecer conocimientos, destrezas y actitudes bajo la pedagógica de la solución de problemas, siendo la forma más efectiva para aprender haciendo y crear un pensamiento crítico que acompañe al profesional de salud durante su vida.
Posicionamiento de emprendimientos en artesanos, provincia de Santa Elena
Authors: Castro Loor Divar Sebastian , Calderón Pineda Fausto Vinicio , Castro Rodas Divar Efraín , Rodas Idrovo Rosa Amada
Published: December 2022

El emprendimiento en la economía se constituye en una herramienta natural de MiPyME, permite afianzar ideas de negocios con productividad y competitividad. En la actualidad postpandemia-COVID-19- se ha reactivado la actividad empresarial, así como las iniciativas familiares de emprendimiento. El objetivo de la investigación es analizar las debilidades existentes en el posicionamiento de emprendimientos en el mercado artesanal de la asociación “Formando Hombres y Mujeres Artesanas” del cantón La Libertad. La metodología aplicada, fue desarrollada con un enfoque cualitativo y cuantitativo, con técnicas de recolección de datos por medio de la encuesta y observación directa; se realizó el cálculo resultante de confiabilidad en lo referente al coeficiente Alfa de Cronbach con 0,7538322; ubicándose en un rango de magnitud alta, por lo que se identifica la incidencia de las estrategias y herramientas para la gestión de marcas en el posicionamiento de las artesanías de la provincia. Los resultados muestran falencias en la oferta de productos, por el desconocimiento sobre la gestión de marca.
Evolución de la Economía Popular y Solidaria y su impacto en el desarrollo social-productivo del Ecuador, 2008-2021
Authors: León Serrano Lady Andrea , Bustos Carpio Gisella Esthela , Pardo Asanza Fernando Alberto
Published: December 2022

Sin duda alguna, la Economía Popular y Solidaria se desarrolló como un importante factor dentro de la economía del Ecuador durante el período 2008-2021, al tener como principal motor reducir la desigualdad social y financiera, por medio de políticas transparentes, sólidas e innovadoras. El objetivo de esta investigación fue analizar la evolución de la Economía Popular y Solidaria, destacando su impacto sobre el desarrollo social y productivo del Ecuador durante este período, mediante la recolección de datos estadísticos de las variables intervenidas. Se trató de un análisis de tipo descriptivo-documental, los datos se recogieron a partir de una investigación con diseño no experimental y de corte longitudinal. Los resultados, por medio de la estimación, demostraron la estrecha relación que presentan la Economía Popular y Solidaria y el crecimiento económico, a través de la ampliación del desarrollo productivo y reducción de los niveles de desempleo y pobreza.
GRAPHENE OXIDE BASED TRANSPARENT RESINS FOR ACCURATE 3D PRINTING OF CONDUCTIVE MATERIALS
Authors: Tilve-Martinez David , Neri Wilfrid , Horaud Dylan , Vukadinovic Nicolas , Berton Benoit , Yuan Jinkai , Poulin Philippe
Published: December 2022

Digital Light Processing (DLP) allows the fast realization of 3D objects with high spatial resolution. However, DLP is limited to highly transparent resins, and therefore not well suited for printing electrically conductive materials. Manufacturing conductive materials would significantly broaden the spectrum of applications of the DLP technology. But conductive metal or carbon based fillers absorb and scatter light; inhibiting thereby photopolymerization, and lowering 3D printing resolution. In this work, UV transparent liquid crystal graphene oxide (GO) is used as precursor for generating in-situ conductive particles. The GO materials are added to a photopolymerizable resin via an original solvent exchange process. By contrast to earlier contributions, the absence of drying during the all process allows the GO material to be transferred as monolayers to limit UV scattering. The absence of UV scattering and absorption allows for fast and high-resolution 3D printing. The chosen resin sustain high temperature to enable an in-situ efficient thermal reduction of GO into reduced graphene oxide rGO which is electrically conductive. The rGO particles form percolated networks with conductivities up to 1.2·10-2 S·m-1. The present method appears therefore as a way to reconcile the DLP technology with the manufacturing of 3D electrically conductive objects.
Density Functional Tight-Binding Model for Lithium-Silicon Alloys.
Authors: Oviedo Ma. Belén , Fernandez Francisco , Otero Manuel , Leiva Ezequiel , Paz S. Alexis
Published: December 2022

The predictive power of molecular dynamic simulations is mainly restricted by the time scale and model accuracy. Many systems of current relevance are of such complexity that requires addressing both issues simultaneously. This is the case of silicon electrodes in Li-ion batteries, where different Li$_x$Si alloys are formed during charge/discharge cycles. While first-principles treatments for this system are seriously limited by the computational cost of exploring its large conformational space, classical force-fields are not transferable enough to represent it accurately. Density Functional Tight-Binding (DFTB) is an intermediate complexity approach capable of capturing the electronic nature of different environments with a relatively low computational cost. In this work, we present a new set of DFTB parameters suited to model amorphous Li$_x$Si alloys. The latter is the usual finding upon cycling the Si electrodes in the presence of Li-ions. The model parameters are constructed with a particular emphasis on their transferability for the entire Li$_x$Si composition range. This is achieved by introducing a new optimization procedure that weights stoichiometries differently to improve the prediction of their formation energies. The resulting model is shown to be robust for predicting crystal and amorphous structures for the different compositions, giving excellent agreement with DFT calculations and outperforming state-of-the-art ReaxFF potentials.
Enhancing Semiempirical Quantum Mechanical Scoring with Machine Learning: a new scoring function that accounts for both the enthalpic and entropic contributions to the ligand binding free energy
Authors: Evangelidis Thomas , Giassa, Ilektra-Chara , Lovrić Mario
Published: December 2022

Identifying hit compounds is a principal step in early-stage drug discovery. While many machine learning (ML) approaches have been proposed, in the absence of binding data, molecular docking is the most widely used option to predict binding modes and score hundreds of thousands of compounds for binding affinity to the target protein. Docking's effectiveness is critically dependent on the protein-ligand (P-L) scoring function (SF), thus re-scoring with more rigorous SFs is a common practice. In this pilot study, we scrutinize the PM6-D3H4X/COSMO semi-empirical quantum mechanical (SQM) method as a docking pose re-scoring tool on 17 diverse receptors and ligand decoy sets, totaling 1.5 million P-L complexes. We investigate the effect of explicitly computed ligand conformational entropy and ligand deformation energy on SQM P-L scoring in a virtual screening (VS) setting, as well as molecular mechanics (MM) versus hybrid SQM/MM structure optimization prior to re-scoring. Our results proclaim that there is no obvious benefit from computing ligand conformational entropies or deformation energies and that optimizing only the ligand's geometry on the SQM level is sufficient to achieve the best possible scores. Instead, we leverage machine learning (ML) to include implicitly the missing entropy terms to the SQM score using ligand topology, physicochemical, and P-L interaction descriptors. Our new hybrid scoring function, named SQM-ML, is transparent and explainable, and achieves in average 9% higher AUC-ROC than PM6-D3H4X/COSMO and 3% higher than Glide SP, but with consistent and predictable performance across all test sets, unlike the former two SFs, whose performance is considerably target-dependent and sometimes resembles that of a random classifier. The code to prepare and train SQM-ML models is available at https://github.com/tevang/sqm-ml.git and we believe that will pave the way for a new generation of hybrid SQM/ML protein-ligand scoring functions.
Formation of substituted dioxanes in the oxidation of gum arabic with periodate
Authors: Siebe Harmke S. , Sardjan Andy S. , Massmann Sarina C. , Flapper Jitte , van den Berg Keimpe J. , Eisink Niek , Kentgens Arno P. M. , Feringa Ben L. , Kumar Akshay , Browne Wesley
Published: December 2022

Renewable polysaccharide feedstocks are of interest in bio-based food packaging, coatings and hydrogels. Their physical properties often need to be tuned by chemical modification, e.g. by oxidation using periodate, to introduce carboxylic acid, ketone or aldehyde functional groups. The reproducibility required for application on an industrial scale, however, is challenged by uncertainty about the composition of product mixtures obtained and of the precise structural changes that the reaction with periodate induces. Here, we show that despite the structural diversity of gum arabic, primarily rhamnose and arabinose subunits undergo oxidation, whereas (inchain) galacturonic acids are unreactive towards periodate. Using model sugars, we show that periodate preferentially oxidises the anti 1,2-diols in the rhamnopyranoside monosaccharides present as terminal groups in the biopolymer. While formally oxidation of vicinal diols results in the formation of two aldehyde groups, only traces of aldehydes are observed in solution, with the main final products obtained being substituted dioxanes, both in solution and in the solid state. The substituted dioxanes form most likely by the intramolecular reaction of one aldehyde with a nearby hydroxyl group, followed by hydration of the remaining aldehyde to form a geminal diol. The absence of significant amounts of aldehyde functional groups in the modified polymer impacts crosslinking strategies currently attempted in the preparation of renewable polysaccharide-based materials.
Electrochemical Synthesis of Bismuth Iodide and Bismuth Oxyiodide
Authors: Govindaraju Mohan Kumar , Varma Deepak Suresh , Jothi Sathiskumar , Ramasamy Devaraj , Abrantes João , Rangarajan Murali
Published: December 2022

This study reports the electrochemical synthesis of bismuth iodide and bismuth oxyiodide from acidic baths containing bismuth nitrate, sodium nitrate, iodine and ethylene glycol by a simple pH control. Linear sweep voltammetry analyses determined the potential window for the reduction of iodine where bismuth ion does not get reduced. The concentration of the iodide ions in the bath is regulated by the applied potential and the equilibrium that exists between iodine-iodide and nitrate-nitrite pairs. At pH 0.2 and 0.5, bismuth is predominantly present as free Bi3+ ions, which react with iodide to form bismuth triiodide. On the other hand, even at slightly elevated pH 1.0 and 2.0, bismuth is predominantly complexed by water, nitrates and ethylene glycol. These complexes react with the iodide ions to form bismuth oxyiodide. X-ray diffraction confirms that bismuth oxyiodide is predominantly formed at higher pH (1.0 and 2.0), while at lower pH (0.2 and 0.5), bismuth triiodide is formed. Impedance spectra are consistent with the above mechanism. The deposited bismuth oxyiodide films exhibit a cactus-like morphology formed from interlinked nano-disks, while the bismuth iodide films form micron-size platelet crystallites, both with good surface coverage. X-ray photoelectron spectroscopy confirms the formation of pure BiI3 at pH 0.2, while binding energies of Bi 4f state in pure BiOI prepared at pH 2.0 has a slight shift towards higher binding energies. From diffuse reflectance spectroscopy studies, indirect bandgaps of electrochemically synthesized BiI3 and BiOI were found to be 1.72 eV and 1.98 eV, respectively.
Respiratory Allergy : A Growing Phenomenon and its Management
Authors: Sarangdhar Nikhil
Published: December 2022

None
Sevelamer in Management of Hyperphosphataemia in Chronic Kidney Disease
Authors: Shankar PS
Published: December 2022

None
The Effect of Dexmedetomidine Dosage on Duration of Spinal Anaesthesia using Hyperbaric Bupivacaine for Abdominal and Lower Extremity Surgeries
Authors: V. Yashoda and Dr. Milind S. Hatwalne Dr.
Published: December 2022

None
Bentall with Total Arch Replacement using Long Elephant Trunk (TARLET) for Marfan’s Syndrome
Authors: Shah Swati
Published: December 2022

Aortic arch surgery requires meticulous teamwork in the true perioperative sense. Planning and communication at all phases from preoperative evaluation through intraoperative management to postoperative care should be well coordinated between surgical anesthesia perfusion and intensive care unit teams. This case report discusses intraoperative management of a case of Marfanrsquos syndrome with anomalous right subclavian artery from the anesthesiologistrsquos perspective. Bentall with Total Arch Replacement using Long Elephant Trunk for Marfanrsquos syndrome with anomalous right subclavian artery was performed. Stanford type A dissection of the aorta extending down till the bifurcation can affect multi-organs system besides brain. An intraoperative strategy should aim multi-organ protection to avoid morbidity and mortality. Cerebral protection using retrograde and antegrade cerebral perfusion and systemic hypothermic circulatory arrest to protect multi organs made surgery and post-operative recovery uneventful.
De novo discovery of traits co-occurring with chronic obstructive pulmonary disease
Authors: Golovina Evgeniia , Fadason Tayaza , Jaros Rachel K , Kumar Haribalan , John Joyce , Burrowes Kelly , Tawhai Merryn , O’Sullivan Justin M
Published: December 2022

Chronic obstructive pulmonary disease (COPD) is a heterogeneous group of chronic lung conditions. Genome-wide association studies have identified single-nucleotide polymorphisms (SNPs) associated with COPD and the co-occurring conditions, suggesting common biological mechanisms underlying COPD and these co-occurring conditions. To identify them, we have integrated information across different biological levels (i.e., genetic variants, lung-specific 3D genome structure, gene expression and protein–protein interactions) to build lung-specific gene regulatory and protein–protein interaction networks. We have queried these networks using disease-associated SNPs for COPD, unipolar depression and coronary artery disease. COPD-associated SNPs can control genes involved in the regulation of lung or pulmonary function, asthma, brain region volumes, cortical surface area, depressed affect, neuroticism, Parkinson’s disease, white matter microstructure and smoking behaviour. We describe the regulatory connections, genes and biochemical pathways that underlay these co-occurring trait-SNP-gene associations. Collectively, our findings provide new avenues for the investigation of the underlying biology and diverse clinical presentations of COPD. In so doing, we identify a collection of genetic variants and genes that may aid COPD patient stratification and treatment.
APPLICATION OF MACHINE LEARNING IN MODELS
Authors: P Dr Sampath
Published: December 2022

Automatic learning or Machine Learning is a branch of Artificial Intelligence that represents the present and future of the way of understanding the world. Today it is used in a wide variety of problems, from detecting gravitational waves and predicting demand in a financial market, to driving autonomous cars.
Learning Braille at Higher Education Level: Exploring the Perception of Prospective Special Education Teachers
Authors: Iqbal Kashif , Ashraf Samina , Amjad Aqsa
Published: December 2022

Purpose: Braille learning is important for teaching students with visual impairment. This study intended to seek the perception of pre-service teachers who obtain degree in special education with the compulsion of learning Braille.

Design/Methodology/Approach: This was exploratory and qualitative research. The Sample of study included pre-service teachers (N = 21) studying at higher education level. Convenient sampling technique was used to collect data for this study. A self-developed semi-structured interview protocol was instrument to collect data. The validity of the instrument was assured by the expert opinion (N=03). The reliability of the questionnaire was confirmed through an extensive literature review. The data were analyzed through open coding of the interview transcription to draw categories and themes.  There were four major themes emerged i.e challenges in learning Braille, reading techniques, Braille comprehension, and Braille Rules.

Findings: The findings of the study revealed more difficulty in reading Braille in grade two as compare to Braille writing, no training in the haptic sense in higher education institutes, and a lack of proper training courses in teaching and learning braille.

Implications/Originality/Value: The study recommends appropriate support by the institutes and particular trainings and courses for Braille learning.
Influence of Customer Relation Management, Service Quality on Customer Trust
Authors: Yunaz Haswan , Suryasaputra Ruswiati , Muliyati Muliyati
Published: December 2022

Objective: Technological developments and increasing living standards make people aware of the importance of a service. The development of Small and Medium Industries is closely related to the Ministry of Industry, especially business licenses. The Ministry of Industry as a public service should always improve the services provided to the community. This research was carried out in Small and Medium Industries as users of the Ministry of Industry's Public Center Service Unit.

The purpose of the study is to determine the effect of customer relationship management, service quality and trust in Small and Medium Industries partially, simultaneously and its implications on customer trust in the Central Public Service Unit of the Ministry of Industry.

Methodology: The problem is formulated in 3 hypotheses and tested by Structural Equation Modeling (LISREL 8.30) with 350 respondents. Findings: It is concluded that Hypothesis one (H1) Customer Relationship Management has a positive effect on customer trust, has a value of t>2 (3.57> 2). The influence of Customer Relationship Management  on customer trust is 0.39. The second hypothesis (H2) Service Quality has a positive and significant effect on customer trust, the value of t>2 (2.32>2) and if service quality is improved, customer trust in the Ministry's Central Public Service Unit will increase by 22%.  The third hypothesis (H3) Customer Relationship Management (CRM) and Service Quality simultaneously have a positive and significant effect on customer trust, the value of t > 2 (7.12> 2) and the magnitude of the effect is 0.71.  

Implications: The Central Public Service Unit of the Ministry of Industry should provide maximum service so that consumers become loyal customers.