bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital Trail Awareness in Islamic Perspective
Authors: Adnan Gunawan , Fadhli Mulkan , Ashal Farid Fathony
Published: February 2022

Abstract: The growing popularity of the internet has a significant impact on people's attitudes. The Covid-19 pandemic has accelerated a cultural, ethical, and normative change in people's behavior. The potential for social change resulting from the emergence or advancement of information and technology is significant. The rise of social media, which has now become a common form of communication, is unavoidable. Digital communication through a variety of websites to obtain information will leave digital traces. The concept of a digital trail certainly reaffirms what has previously been written in Al-Qur'an, Surah Yasin: 65. This verse is relevant to digital multi-hop tracks that outline human actions and behavior to the swipe of their fingers. The verse is translated through the use of a digital trail that is connected to internet access. This library research study uses the source triangulation method to analyse exploratory qualitative content. The study's findings indicate a correlation between the digital trail and Surah Yasin 65, demonstrating that current digital technology proves that the Qur'an's nash or verses are consistent with the unquestionable assumption of human rationality. It also emphasizes the importance of being cautious and responsible when using digital platforms.Abstrak: Tren peningkatan penggunaan internet memberikan pengaruh besar terhadap perilaku masyarakat. Pandemi Covid-19 mengakselerasi pergeseran pola perilaku masyarakat baik dari segi budaya etika maupun norma yang ada. Potensi terjadinya perubahan sosial sebagai konsekuensi lahir atau berkembangnya teknologi informasi sangat besar. Kemunculan media sosial yang kini sudah menjadi hal yang umum dalam berkomunikasi memang tak dapat dihindarkan lagi. Jalur komunikasi di era digital yang melalui berbagai proses untuk mendapatkan informasi akan meninggalkan jejak-jejak digital atau digital footprint. Potret jejak digital ini tentunya menegaskan kembali apa yang telah dituliskan dalam Al Quran pada surah Yasin ayat 65. Ayat ini memiliki relevansi dengan jejak hop digital menguraikan perbuatan dan perilaku manusia dari sentuhan jari. Ayat tersebut diterjemahkan dengan footprint digital yang terhubung dalam sebuah jaringan internet. Studi ini merupakan library research dengan  pendekatan kualitatif explanatif dalam bentuk konten analisis dengan metode tringalasi sumber. Hasil studi menunjukkan bahwa terdapat korelasi digital footprint dengan Surah Yasin 65 di mana teknologi digital saat ini menjadi bukti bahwa nash yang termuat dalam Alquran sesuai dengan asumsi rasionalitas manusia yang tidak memiliki keraguan di dalamnya. Penekanan berikutnya adalah setiap individu harus cermat dan bertanggungjawab dalam mengakses platform digital.
Effectiveness Bleaching of Waste Cooking Oil Cleaning Using Nano-Montmorillonite Adsorbent
Authors: Ningsih Silvia , Wahyuningsih Puji , Harmawan Tisna
Published: February 2022

Abstract: Waste cooking oil contains carcinogenic compounds which are formed during the frying process. The content change makes it is not worth for reuse cooking oil. One of the damages to cooking oil is caused by heating. The quality of useable oil refers to SNI 01-3741-2013. The sample used in this research is waste cooking oil that is used for 5 times of frying. The quality of the oil can be improved using Nano-Montmorillonite adsorbent. The results of PSA and FTIR characterization show that Nano-Montmorillonite has a nano-scale particle size of 15.3 nm with a percentage of 6%. The rest are particles that have a size> 100 nm with a total percentage of 94% with a respective size of 383.9 nm with a percentage of 59% and 6647.1 nm with a percentage of 35% and have functional groups, namely hydroxyl (-OH), Si-O-Si and Al-Al-OH. Testing of waste cooking oil quality includes organoleptic, acid numbers, peroxide numbers, and saponification numbers using Nano-Montmorillonite. Based on the results, the more Nano-Montmorillonite adsorbent was added, the lower the numbers of acid, peroxide, and saponification in waste cooking oil and the better the quality of flavor and color. Based on this analysis, Nano-Montmorillonite adsorbent can improve the quality of waste cooking oil.Abstrak: Minyak jelantah mengandung senyawa yang bersifat karsinogenik yang terbentuk selama proses penggorengan. Perubahan sifat ini menjadikan minyak goreng tersebut tidak layak digunakan kembali sebagai bahan makanan. Salah satu kerusakan pada minyak goreng disebabkan oleh pemanasan. Kualitas minyak layak pakai merujuk pada SNI 01-3741-2013. Sampel minyak yang digunakan dalam penelitian ini adalah  minyak jelantah dengan 5 kali penggorengan. Kualitas minyak tersebut dapat ditingkatkan menggunakan adsorben Nano-Montmorillonit. Berdasarkan hasil karakterisasi PSA dan FTIR menunjukkan bahwa Nano-Montmorillonit memiliki ukuran partikel berskala nano yaitu 15,3 nm dengan persentase sebesar 6% dan sisanya merupakan partikel yang memiliki ukuran > 100 nm dengan total persentase 94% dengan ukuran masing-masing sebesar 383,9 nm dengan persentase 59% dan 6647,1 nm dengan persentase 35%serta memiliki gugus-gugus fungsional yaitu hidroksil (-OH), Si-O-Si dan Al-Al-OH. Pengujian kualitas minyak jelantah meliputi organoleptik, bilangan asam, bilangan peroksida dan bilangan penyabunan menggunakan Nano-Montmorillonit. Berdasarkan hasil pengujian maka semakin banyak jumlah adsorben Nano-Montmorilonit yang ditambahkan maka bilangan asam, bilangan peroksida, bilangan penyabunan mengalami penurunan serta kualitas aroma dan warna pada minyak jelantah menjadi lebih baik. Berdasarkan analisis tersebut adsorben Nano-Montmorillonit dapat meningkatkan kualitas minyak jelantah.
Bladder Melanosis
Authors: Hogan Donnacha , Mayer Nick , Hennessey Derek Barry
Published: February 2022

This case report describes a rare cystoscopic finding in an octogenarian, presenting initially with nonspecific lower urinary tract symptoms. Physical examination did not reveal any abnormal skin or mucoepidermoid pigmentation. Routine ultrasound identified cystic changes in the bladder prompting cystoscopic investigation. Flexible cystoscopy identified melanin deposits within the bladder mucosa, and biopsy subsequently confirmed a diagnosis of bladder melanosis. The authors of this report wish to add to the available literature on this extremely rare finding in the hope a more robust evidence base would allow a protocol to be established for follow-up. The ultrasound findings reported in this study have not been previously reported and may benefit future guidelines on diagnosis.
COVID-19: Psychosocial impact and mental health in Latin America
Authors: GALLEGOS M. , Consoli Andrés , FERRARI I. F. , CERVIGNI MAURICIO , de Castro V. , Martino Pablo , Caycho Tomás , Razumovskiy Anastasia
Published: February 2022

The COVID-19 pandemic has not only had health, economic, and political impacts, but also significant psychosocial and mental health consequences worldwide. In this article, different documentation and studies on mental health were analyzed, with the aim of identifying the various problems detected during the pandemic. Methodologically, a narrative and integrative review of the scientific literature was carried out. In Latin America, the most recent studies have documented and made patent effects on the various vulnerized populations such as migrants, women, children, the elderly, people living with significant disabilities, people experiencing marked housing and food insecurity, and temporary workers laboring in what has been referred to as the informal economy. In light of this, it is proposed that addressing these issues should involve the coordination of transnational policies and the definition of an agenda of critical priorities to focus and address. For this to come about, it is important that the empirical evidence generated by regional epidemiological studies contribute to the design of public policies on mental health of the Latin American population, so that they reduce the negative effects as well as prevent the future consequences of a pandemic that is not yet over.
Hepatite B: um alerta aos cirurgiões-dentistas
Authors: Gonzalez Bruna Ponce Calixto , Pinho Carolina De Jesus Meireles Ribeiro , Correa Joelma Elias de Jesus , Medeiros Yuri De Lima , Guimarães Leticia Drumond de Abreus , Vilela Eduardo Machado
Published: February 2022

Aim: Despite the availability and guidance regarding the hepatitis B virus (HBV) vaccination, it is observed that the vaccine coverage and knowledge among dental professionals are not satisfactory, especially in developing countries. As a warning to dental students and professionals, the aim of this study is to review the literature on HBV infection in dental practice. Materials and methods: This is a narrative review. The articles included were searched in the Pubmed, Scielo and Lilacs databases, using the descriptors "Hepatitis B virus" and "Dentist", from 2000 to 2020. Literature review: Knowledge about HBV should be encouraged during graduation, since dentists play an important role in preventing this disease. Hepatitis B is more prevalent among dentists than in the general population. In these professionals, the transmission occurs mainly due to a percutaneous injury involving the use and disposal of cutting instruments contaminated with the infected patient's blood or saliva. In addition, as nasopharyngeal secretions carry the virus, although remote, there is still the possibility of aerosol infection. Discussion: Among the forms of prevention, we can mention the accomplishment of the complete vaccination schedule, the guidelines for the dental management of patients with hepatitis, the adoption of biosafety standards and the correct methods for cleaning, disinfecting and sterilizing the materials. Conclusion: Dentists have higher risk of exposure to HBV infection than the rest of the population. Therefore, these professionals must pay special attention to strategies for preventing hepatitis.
Exploring the Impact of Human Resource Management Practices on Employee's Retention: Evidence from the Food and Beverage Industry in the State of Qatar
Authors: Awolusi Olawumi Dele , Jayakody Shirley Shamen
Published: February 2022

Employee turnover is stated as a huge issue concerning business organizations in Qatar. The organizations in the food and beverage industry of Qatar try to retain the employees by using suitable and appropriate human resource policies. Consequently, the paper analyzed the influence of human resources management practices on employee’s retention in the food and beverage industry of Qatar. In the present study, the researcher used a simple random sampling method to select the employees in the F&B industry in Qatar to minimize the chances of sampling error or fluctuations and biases in the data. According to the sample size calculation, 41 samples were used for data collection. But only 35 respondents were given responses to questionnaire filling. Therefore, 35 samples were only used in this study. Thus, a survey questionnaire was the research instrument. The questionnaire contained 14 close-ended questions, divided, into two sections, demographic and non-demographic. Considering the study objectives, the quantitative, data analysis method was applied in this study. The survey responses were converted into numeric values as those were collected through a replicable scale. Inferential, reliability, correlation and multiple regression analysis were applied to test the hypotheses. The study concluded that HR Recruitment policy, Training, and development program, Performance appraisal system; Reward system are important determinants of employee retention in the food and beverage industry of Qatar. Specifically, the reasons for increasing employee's turnover are lack of growth opportunities, poor communication, improper promotional activities, and misalignment of culture and value system, lack of decision-making ability, employee welfare, work-life imbalance and regular changes in job responsibilities. The study, therefore, recommended the following: greater employee’s involvement in the HRM policy formulation and implementation, improved employee’s compensation, social recognition, efficient top management support, as well as improved training and development in the food and beverage industry in Qatar.
Nrf2 Regulates β-Cell Mass by Suppressing β-Cell Death and Promoting β-Cell Proliferation
Authors: Baumel-Alterzon Sharon , Katz Liora S. , Brill Gabriel , Jean-Pierre Clairete , Li Yansui , Tse Isabelle , Biswal Shyam , Garcia-Ocaña Adolfo , Scott Donald K.
Published: February 2022

Finding therapies that can protect and expand functional β-cell mass is a major goal of diabetes research. Here, we generated β-cell–specific conditional knockout and gain-of-function mouse models and used human islet transplant experiments to examine how manipulating Nrf2 levels affects β-cell survival, proliferation, and mass. Depletion of Nrf2 in β-cells results in decreased glucose-stimulated β-cell proliferation ex vivo and decreased adaptive β-cell proliferation and β-cell mass expansion after a high-fat diet in vivo. Nrf2 protects β-cells from apoptosis after a high-fat diet. Nrf2 loss of function decreases Pdx1 abundance and insulin content. Activating Nrf2 in a β-cell–specific manner increases β-cell proliferation and mass and improves glucose tolerance. Human islets transplanted under the kidney capsule of immunocompromised mice and treated systemically with bardoxolone methyl, an Nrf2 activator, display increased β-cell proliferation. Thus, by managing reactive oxygen species levels, Nrf2 regulates β-cell mass and is an exciting therapeutic target for expanding and protecting β-cell mass in diabetes.
Endothelial Phospholipase Cγ2 Improves Outcomes of Diabetic Ischemic Limb Rescue Following VEGF Therapy
Authors: Rustagi Yashika , Abouhashem Ahmed S. , Verma Priyanka , Verma Sumit S. , Hernandez Edward , Liu Sheng , Kumar Manishekhar , Guda Poornachander R. , Srivastava Rajneesh , Mohanty Sujit K. , Kacar Sedat , Mahajan Sanskruti , Wanczyk Kristen E. , Khanna Savita , Murphy Michael P. , Gordillo Gayle M. , Roy Sashwati , Wan Jun , Sen Chandan K. , Singh Kanhaiya
Published: February 2022

Therapeutic vascular endothelial growth factor (VEGF) replenishment has met with limited success for the management of critical limb-threatening ischemia. To improve outcomes of VEGF therapy, we applied single-cell RNA sequencing (scRNA-seq) technology to study the endothelial cells of the human diabetic skin. Single-cell suspensions were generated from the human skin followed by cDNA preparation using the Chromium Next GEM Single-cell 3′ Kit v3.1. Using appropriate quality control measures, 36,487 cells were chosen for downstream analysis. scRNA-seq studies identified that although VEGF signaling was not significantly altered in diabetic versus nondiabetic skin, phospholipase Cγ2 (PLCγ2) was downregulated. The significance of PLCγ2 in VEGF-mediated increase in endothelial cell metabolism and function was assessed in cultured human microvascular endothelial cells. In these cells, VEGF enhanced mitochondrial function, as indicated by elevation in oxygen consumption rate and extracellular acidification rate. The VEGF-dependent increase in cell metabolism was blunted in response to PLCγ2 inhibition. Follow-up rescue studies therefore focused on understanding the significance of VEGF therapy in presence or absence of endothelial PLCγ2 in type 1 (streptozotocin-injected) and type 2 (db/db) diabetic ischemic tissue. Nonviral topical tissue nanotransfection technology (TNT) delivery of CDH5 promoter–driven PLCγ2 open reading frame promoted the rescue of hindlimb ischemia in diabetic mice. Improvement of blood flow was also associated with higher abundance of VWF+/CD31+ and VWF+/SMA+ immunohistochemical staining. TNT-based gene delivery was not associated with tissue edema, a commonly noted complication associated with proangiogenic gene therapies. Taken together, our study demonstrates that TNT-mediated delivery of endothelial PLCγ2, as part of combination gene therapy, is effective in diabetic ischemic limb rescue.
Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle
Authors: Larsen Jeppe K. , Larsen Magnus R. , Birk Jesper B. , Steenberg Dorte E. , Hingst Janne R. , Højlund Kurt , Chadt Alexandra , Al-Hasani Hadi , Deshmukh Atul S. , Wojtaszewski Jørgen F.P. , Kjøbsted Rasmus
Published: February 2022

Insulin-stimulated muscle glucose uptake is a key process in glycemic control. This process depends on the redistribution of glucose transporters to the surface membrane, a process that involves regulatory proteins such as TBC1D1 and TBC1D4. Accordingly, a TBC1D4 loss-of-function mutation in human skeletal muscle is associated with an increased risk of type 2 diabetes, and observations from carriers of a TBC1D1 variant associate this protein to a severe obesity phenotype. Here, we identified interactors of the endogenous TBC1D4 protein in human skeletal muscle by an unbiased proteomics approach. We detected 76 proteins as candidate TBC1D4 interactors. The binding of 12 of these interactors was regulated by insulin, including proteins known to be involved in glucose metabolism (e.g., 14-3-3 proteins and α-actinin-4 [ACTN4]). TBC1D1 also coprecipitated with TBC1D4 and vice versa in both human and mouse skeletal muscle. This interaction was not regulated by insulin or exercise in young, healthy, lean individuals. Similarly, the exercise- and insulin-regulated phosphorylation of the TBC1D1-TBC1D4 complex was intact. In contrast, we observed an altered interaction as well as compromised insulin-stimulated phosphoregulation of the TBC1D1-TBC1D4 complex in muscle of obese individuals with type 2 diabetes. Altogether, we provide a repository of TBC1D4 interactors in human and mouse skeletal muscle that serve as potential regulators of TBC1D4 function and, thus, insulin-stimulated glucose uptake in human skeletal muscle.
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination
Authors: Niu Yuguo , Jiang Haizhou , Yin Hanrui , Wang Fenfen , Hu Ronggui , Hu Xiaoming , Peng Bo , Shu Yousheng , Li Zhigang , Chen Shanghai , Guo Feifan
Published: February 2022

Chronic inflammation in liver induces insulin resistance systemically and in other tissues, including the skeletal muscle (SM); however, the underlying mechanisms remain largely unknown. RNA sequencing of primary hepatocytes from wild-type mice fed long-term high-fat diet (HFD), which have severe chronic inflammation and insulin resistance revealed that the expression of hepatokine endoplasmic reticulum aminopeptidase 1 (ERAP1) was upregulated by a HFD. Increased ERAP1 levels were also observed in interferon-γ–treated primary hepatocytes. Furthermore, hepatic ERAP1 overexpression attenuated systemic and SM insulin sensitivity, whereas hepatic ERAP1 knockdown had the opposite effects, with corresponding changes in serum ERAP1 levels. Mechanistically, ERAP1 functions as an antagonist-like factor, which interacts with β2 adrenergic receptor (ADRB2) and reduces its expression by decreasing ubiquitin-specific peptidase 33–mediated deubiquitination and thereby interrupts ADRB2-stimulated insulin signaling in the SM. The findings of this study indicate ERAP1 is an inflammation-induced hepatokine that impairs SM insulin sensitivity. Its inhibition may provide a therapeutic strategy for insulin resistance–related diseases, such as type 2 diabetes.
Risk factors for overcorrection of severe hyponatremia: a post hoc analysis of the SALSA trial
Authors: Yang Huijin , Yoon Songuk , Kim Eun Jung , Seo Jang Won , Koo Ja-Ryong , Oh Yun Kyu , Jo You Hwan , Kim Sejoong , Baek Seon Ha
Published: February 2022

Background: Hyponatremia overcorrection can result in irreversible neurologic impairment such as osmotic demyelination syndrome. Few prospective studies have identified patients undergoing hypertonic saline treatment with a high risk of hyponatremia overcorrection. Methods: We conducted a post hoc analysis of a multicenter, prospective randomized controlled study, the SALSA trial, in 178 patients aged above 18 years with symptomatic hyponatremia (mean age, 73.1 years; mean serum sodium level, 118.2 mEq/L). Overcorrection was defined as an increase in serum sodium levels by >12 or 18 mEq/L within 24 or 48 hours, respectively. Results: Among the 178 patients, 37 experienced hyponatremia overcorrection (20.8%), which was independently associated with initial serum sodium level (≤110, 110–115, 115–120, and 120–125 mEq/L with 7, 4, 2, and 0 points, respectively), chronic alcoholism (7 points), severe symptoms of hyponatremia (3 points), and initial potassium level (<3.0 mEq/L, 3 points). The NASK (hypoNatremia, Alcoholism, Severe symptoms, and hypoKalemia) score was derived from four risk factors for hyponatremia overcorrection and was significantly associated with overcorrection (odds ratio, 1.41; 95% confidence interval, 1.24–1.61; p < 0.01) with good discrimination (area under the receiver-operating characteristic [AUROC] curve, 0.76; 95% CI, 0.66–0.85; p < 0.01). The AUROC curve of the NASK score was statistically better compared with those of each risk factor. Conclusion: In treating patients with symptomatic hyponatremia, individuals with high hyponatremia overcorrection risks were predictable using a novel risk score summarizing baseline information.
Parathyroidectomy versus cinacalcet in the treatment of tertiary hyperparathyroidism after kidney transplantation: a retrospective study
Authors: Jung Suyun , Kim Hyosang , Kwon Hyunwook , Shin Sung , Kim Young Hoon , Kim Won Woong , Sung Tae-Yon , Lee Yu-Mi , Chung Ki-Wook , Park Su-Kil , Baek Chung Hee
Published: February 2022

Background: Hyperparathyroidism is common in patients with chronic kidney disease with reduced renal function and has been observed after kidney transplantation. The optimal treatment for cases in which hyperparathyroidism persists after kidney transplantation has not been determined. Methods: This retrospective study included 83 patients with tertiary hyperparathyroidism who underwent kidney transplantation between 2000 and 2018 at a single tertiary center in Korea. Sixty-four patients underwent parathyroidectomy and 19 patients were treated with cinacalcet following renal transplantation. Biochemical parameters and clinical outcomes were compared between the two groups. Results: Serum calcium and parathyroid hormone (PTH) levels improved in both the parathyroidectomy and cinacalcet groups. One year after treatment, parathyroidectomy resulted in a lower mean serum calcium level than cinacalcet (9.7 ± 0.7 mg/dL vs. 10.5 ± 0.7 mg/dL, p = 0.001). Regarding serum PTH, the parathyroidectomy group showed a significantly lower PTH level than the cinacalcet group at 6 months (129.1 ± 80.3 pg/mL vs. 219.2 ± 92.5 pg/mL, p = 0.002) and 1 year (118.8 ± 75.5 pg/mL vs. 250.6 ± 94.5 pg/ mL, p < 0.001). There was no statistically significant difference in the incidence of kidney transplant rejection, graft failure, cardiovascular events, fracture risk, or bone mineral density changes between the two groups. Conclusion: Parathyroidectomy appears to reduce PTH and calcium levels effectively in tertiary hyperparathyroidism. However, creatinine level and allograft rejection should be monitored closely.
Why should we focus on high-volume hemodiafiltration?
Authors: Shin Sug-Kyun , Jo Young-Il
Published: February 2022

Though noticeable technological advances related to hemodialysis (HD) have been made, unfortunately, the survival rate of dialysis patients has yet to improve significantly. However, recent research findings reveal that online hemodiafiltration (HDF) significantly improves patient survival in comparison to conventional HD. Accordingly, the number of patients receiving online HDF is increasing. Although the mechanism driving the benefit has not yet been fully elucidated, survival advantages are mainly related to the lowering of cardiovascular mortality. High cardiovascular mortality among HD patients is seemingly attributable to the cardiovascular changes that occur in response to renal dysfunction and the HD-induced myocardial stress and injury, and online HDF appears to improve such secondary cardiovascular changes. Interestingly, patient survival improves only if the convection volume is supplied sufficiently over a certain level during online HDF treatment. In other words, survival improvement from online HDF is related to convection volume. Therefore, there is a growing interest in high-volume HDF in terms of improving the survival rate. The survival improvement will require a minimum convection volume of 23 L or more per 4-hour session for postdilution HDF. To obtain an optimal high convection volume in online HDF, several factors, such as the treatment time, blood flow rate, filtration fraction, and dialyzer, need to be considered. High-volume HDF can be performed easily and safely in routine clinical practice. Therefore, when the required equipment is available, performing high-volume HDF will help to improve the survival rate of dialysis patients.
Química e Saúde Pública: Elementos da História de uma relação fundamental
Authors:   Universidade de Coimbra, CQC Departamento de Química, Rodrigues Sérgio P. J.
Published: February 2022

A química teve, a partir do final do século XVIII, um papel central, que se mantém na atualidade, na saúde pública e no bem-estar da humanidade. A sua maior contribuição é na segurança alimentar, que contribuiu para salvar as vidas de cerca de um terço da população humana. O tratamento da água de consumo com cloro contribuiu para salvar da morte prematura quase duzentos milhões de pessoas. Doenças como a febre tifoide, que mataram reis, como D. Pedro V, e a cólera, são hoje essencialmente memórias. Os antibióticos contribuíram para quase eliminar a sífilis e outras infeções. A tuberculose e a malária quase desapareceram na Europa, em boa parte devido à química. Também a assepsia, a anestesia e a segurança das transfusões de sangue e das vacinas devem muito a contribuições químicas. Atualmente, estamos a viver uma situação de pandemia global, mas devido, também à ciência, podemos enfrentar os problemas com esperança. O principal objetivo do presente trabalho é fazer uma revisão histórica das contribuições químicas para a saúde pública e bem-estar, algo que parecendo trivial, raramente é compreendido em toda a sua extensão.
Analysis of the results of triaxial tests of cohesive soils in the Omsk region
Authors:   The Siberian State Automobile and Highway University, Prolygin A. S. , Dolgih G. V. ,   The Siberian State Automobile and Highway University, Aleksandrov A. S. ,   The Siberian State Automobile and Highway University
Published: February 2022

The paper presents the analysis results of experimental values of adhesion and the internal friction angle for total and effective stresses obtained on the basis of triaxial tests of cohesive soils in the Omsk region. The calculated values of the shear resistance characteristics of heavy loam for the design of road clothes in the Omsk region are proposed.
International architectural practice.Postgraduate practical training of architects
Authors:   Saint Petersburg State University of Architecture and Civil Engineering, Liavdansky V. Eh.
Published: February 2022

Modern architectural practice offers such forms of training that provide the very possibility of practical realization of young architects` creative vision and professional potential. Various directions of post-graduate practical training are described, and their impact on the results of creative and professional activity of architects is analyzed. The consequences of the introduction of practical training model for architects in the Russian Federation are speculated upon.
EMPOWERMENT OF BUSINESS SERVICE COOPERATIVES PASIR BATANG SEJAHTERA IN CREATIVE ECONOMIC DEVELOPMENT OF THE COFFEE SECTOR, KARANGSARI VILLAGE, KUNINGAN REGENCY
Authors: Mariane Ine , Palls Aswin , Ariesmansyah Andre
Published: February 2022

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Sosialisasi Bahaya Media Sosial sebagai Modus Perdagangan Orang pada Remaja di Jatinangor
Authors: Pratamawaty Benazir Bona , Shinta Dewi Evie Ariadne , Limilia Putri
Published: February 2022

In the period of January to April 2021, 234 children were found to be the victims of the children trafficking and 60% of them were recruited through the social media. Children and young adults were told that they will be hired as employee and earn sophisticated salary while in fact they were tricked into sexual exploitation. Pandemic and high internet penetration results in increasing internet use for children and young adults. Hence, both children and young adults are prone to the human trafficking practices. Therefore, it is urgent to conduct socialization and education towards children and young adults regarding the high risks of social media use as the recruitment tools for human trafficking perpetrators. This community service aimed to increasing knowledge and rising awareness of the young adults in Jatinangor with regard to the threat of social media as the human trafficking modus of practices. The data collection comprised of online survey before and after the socialization. Because of the pandemic, the socialization took place online or known as Webinar. The webinar was divided into three session which consisted of polling session (pre-test), talks and discussion session, then post-test session. The objectives of this webinar were to socialize, educate, and develop social awareness with regard to the human trafficking threats. The online survey results were analyzed using quantitative descriptive technique. The results indicate that after the webinar the participant succeed in gaining knowledge and understanding of the human trafficking recruitment modus and how the social media used as one of the modus.
Uncovering the Relationship between Entrepreneurship Training on Business Growth among SMEs in Southeast Nigeria
Authors: Nuel Okoli Ifeanyi E. , Chika Anugwu Clara
Published: February 2022

The growth of any business is a major concern that is determined by different factors. Entrepreneurship training has been identified as one that can play a key role in the growth of SMEs around the world. The objective of this study was to examine the relationship between entrepreneurship training and business growth among SMEs in Southeast, Nigeria. A survey procedure was accepted for the study and the study was based on both secondary and primary data. The total population of this study is two hundred and fifty (250) small businesses (SMEs). Data were collected using questionnaire and analyzed using Ordinary Least Square Regression. This study revealed that entrepreneurship training has a positive impact on the business growth of the SMEs in Southeast Nigeria. The study concluded that entrepreneurship training is one of the key factors influencing SME growth, as well as the extent to which further training is based on the availability and relevance of training needs and programs. This study recommends that managers and SME owners should develop a good idea for training programs in all areas related to business to help promote and increase the competitiveness of the industry. Also, the government and all stakeholders should invest in entrepreneurship training program for creation of jobs for economic prosperity and sustainability.
The Relationship Between Capital Sructure and Financial Performance of Firms in Ghana and Nigeria
Authors: Opoku-Asante K. , Winful E. C. , Sharifzadeh M. , Neubert M.
Published: February 2022

This study aimed to investigate, using a sectorial analysis, the relationship between capital structure and financial performance and consider the effect of debt maturity on the relationship. the relationship between capital structure and financial performance, considering the debt maturity, using 425 cross-sectional firm-year samples from firms in Ghana and Nigeria from 2014 to 2019. The empirical findings suggested a significant negative relationship between capital structure and financial performance. Debt maturity did not affect the relationship between capital structure and financial performance. However, the Industry influences the direction of the relationship between capital structure and financial performance. Also, debt maturity influences the capital structure performance relationship in specific sectors but not the market. This paper extends on previous studies on the relationship between capital structure and financial performance by incorporating sectorial and debt maturity on firms in Ghana and Nigeria. The findings of this study will assist finance managers in maximizing performance by considering financially sensible heterogeneities such as the sector and the funding source when making financing decisions.
Tolerance of 16-Channel Dense Wavelength Division Multiplexing System to Fibre Dispersion and Four-Wave Mixing under Varying Capacities and Channel Spacing
Authors: Tooki Oluwaseun , Abolade Robert , Aborisade David
Published: February 2022

An essential feature of a long-haul Optical Communication System (OCS) is to transmit huge volumes of data over long distances. In OCS, fiber dispersion and Four-Wave Mixing (FWM) play negative roles in achieving this, as the propagation of the light signal, associated with the pulse, travels at varying speeds. Dense Wavelength Division Multiplexing (DWDM) system is not spared from these identified limitations.  In this work, a mathematical analysis for the dispersion and FWM was presented and validated through simulation software. The research was designed and implemented using an optical simulation software tool, OptiSystem 17.0. Transmission parameters of dispersion and Nonlinear (NL) effects due to refractive index, FWM, were considered.  The research was carried out on a 125 km-long fiber link and was investigated under a 16-channel DWDM system. The effects of identified limitations on the performance of the DWDM system with channel arrangement of 100, 50, and 25 GHz were further explored. This work compared the DWDM system under these different channel arrangements.  The transmission performance of the DWDM system was evaluated based on signal power, noise power, and eye pattern. The results obtained show that any increase in capacity causes significant decreases in the performance of the DWDM system. It was, however, noted that noise power is independent of an increase in bit rate. The results obtained further revealled that the launched power of the system must be reduced for better performance of the DWDM system and improved immunity against identified limitations.
An Application of Artificial Neural Network for Wind Speeds and Directions Forecasts in Airports
Authors: Lawrence E. , Garba E. J. , Malgwi Y. M. , Hambali M. A.
Published: February 2022

Wind speed patterns are highly dynamic and non-linear and thus cannot be accurately forecasted using conventional linear regression models. In this work, Artificial Neural Network (ANN) technique was applied to forecast wind speeds and directions in airports. Monthly data of maximum temperature, minimum temperature, wind speed, wind direction, relative humidity and wind run for Yola International Airport were collected from 1995 to 2021 from Nigerian Meteorological Agency (NIMET) Abuja-Nigeria. Six Neural Network models were built. ANN with no hidden layers, ANN model with one hidden layer and two dropout layers, ANN model with four hidden layers and three dropout layers, ANN model with eight hidden layers, ANN model with nine hidden layers and finally, ANN model with ten hidden layers. Back Propagation training algorithm was implemented using the PYTHON toolbox. Each of the models was trained using the training dataset and validated using the validation dataset. To test the forecasting ability of each of the models we tested it using unknown data that is the test dataset. The results from each of the models were organized and assessed in terms of the magnitude of the statistical error between the measured result and the real data. This was achieved by measuring the average of the Mean Square Errors (MSE) and Mean Absolute Error (MAE) for each of the models used for forecasting both wind speeds and directions. The results show that Multilayer perceptron with ten hidden layers with (MSE) = 0.92 and (MAE) = 0.73 emerged as the most preferred model for wind speeds forecast while the multilayer perceptron with four hidden layers with (MSE) = 1,858 and (MAE) = 35 emerged the most preferred model for wind directions forecast. Future research can be carried out to improve the accuracy of the model for wind direction forecasts.
IMPLEMENTASI KEBIJAKAN PEMBANGUNAN INFRASTRUKTUR JALAN DI KECAMATAN TABIR SELATAN KABUPATEN MERANGIN DENGAN MENGGUNAKAN MODEL DONALD VAN METTER DAN CARL VAN HORN
Authors: Kurniawan Wahyu , Maani Karjuni Dt.
Published: February 2022

Policy implementation are actions taken by individuals or groups of government or private sector to achieve the goals specified in previous policy decisions. This study was designed to describe the six variables of the Donald Van Metter and Carl Van Horn models in the implementation of road infrastructure development policies in the South Tabir District of Merangin Regency which connects Gading Jaya village with Muara Delang village. This type of research is a qualitative descriptive study. There are variable models of Donald Van Metter and Carl Van Horn, standard; destination; and policy objectives, resources, characteristics of implementing organizations, implementers' attitudes, communication between organizations, socio-economic and political environments. PT. SAL and PT. Shogun Judging from the six variables in the Donald Van Metter and Carl Van Horn models in the implementation of road infrastructure development in the South Tabir District has been successfully carried out. This can be seen from having been built with number one quality increased 8.2 Km. This construction has been carried out from 2017 to 2019 with the target of road construction as far as 9.3 Km.
Production and Characterization of Nanoparticles Lipid Carrier (NLCs) Loaded with Red Clover Isoflavones Extract and Their effect on Serum Lipid profile in Postmenopausal Period
Authors: Ali Athraa H.
Published: February 2022

Plant-derived edible nanoparticles (PDNPs) are nano-sized membrane vesicles released by edible plants. They are non-toxic, have tissue-specific targeting properties, and can be mass-produced , to assess the effect of phytoestrogens (PEs) for treating hyperlipidemia that associated with menopause period using nanoparticles lipid carrier (NLCs) loaded with red clover isoflavones extract (RCIE) compared with hormone replacement therapy (HRT). Study was conducted using fifty adult female mice model for menopause using 4-Vinylcyclohexene dioxide (VCD) and handled as follows for 6 weeks. Two experiments were preformed, the first experiment included 20 mice divided into two groups Group A: Control group has injected 0.1 ml D.W. intraperitoneal (IP) daily. Group B: This group has injected IP daily 160 mg/kg B.W of VCD. The second experiment was included 30 mice have injected IP daily 160 mg/kg of VCD and divided into three groups (C, D and E), (10 / group) then treated with dermal sticker for six weeks: Group C: treated with dermal sticker saturated with 10ug/ kg B.W of estradiol benzoate (EB) diluted with virgin coconut oil (VCNO). Group D:  treated with dermal sticker saturated with 0.1 of VCNO.  Group E: treated with dermal sticker saturated with 0.1ml of RCIE-NLCs. The results of statistical analysis showed a significant increase in the level of TC, TG, LDL, and VLDL in group VCD. While RCIE-NLCs had a clear effect  and significant decreased in the TG, TC, LDL and VLDL cholesterol compared to groups VCD and EB, and significant increase in the HDL-C in group RCIE-NLCs compared to groups VCD and EB. The results of this study revealed that administration of RCIE-NLCs shows an effective to regulation of lipids metabolism disorders due to hormonal changes that associated with menopausal transition via impact of VCD.
Criminal offences that infringe on individual freedom versus restrictions imposed during the pandemic to guarantee access to education
Authors: IANCU Elena-Ana , TUȘA Enache
Published: February 2022

In the study we propose as follows, we will look at differences in perception between the pandemic constraints imposed by the governmenst of countries affected by the pandemic in view of managing the pandemic and society’s perception that governments have deprived citizens of their freedom by restricting their mobility and imposing restrictions with regard to travel, including in order to attend educational activities. In some cases, the communities affected by the restrictive measures have gone further, accusing governments of the crime of “Illegal Deprivation of Freedom”, which is included by the legislator in the criminal codes of countries. We consider that the accusations brought against the authorities are unfounded, exaggerated, and thoroughly wrong. We believe that they are due to communication gaps in the public domain, the differences in perception of community members in the context of changing paradigms and the insufficient legal education, which leads to confusion between illegal deprivation of freedom and limitations or restrictions. Although, in the legislation, the articles that provide for the criminal offences relevant to the matter are included in the criminal (penal) codes, for example, in the Romanian legislation in Article 205 of the Criminal Code, with the marginal name “Offences against Individual Freedom” of Title I, which bears the marginal name “Offences against the Person”, and falls within the area of ​​interest of legal sciences, we will analyze the effects in relation to the limitations and restrictions imposed by the authorities for the management of the pandemic. To this end, on the one hand we will highlight the aspects of material criminal law necessary for the legal classification of a deed as offence of illegal deprivation of freedom, in accordance with the provisions of the Criminal Codes of Romania, Hungary, Republic of Italy, Greece, and on the other hand, we will present some aspects regarding the management of the coronavirus crisis in the area of ​​education.
"Godotra várva..." Egy egységes kiberbűnözés elleni egyezmény kodifikációjának kihívásai
Authors: Kerekes László
Published: February 2022

Amióta léteznek számítógépek, azóta létezik a számítógépes bűnözés kategóriája. És mivel létezik számítógépes bűnözés, a nemzetközi- nemzeti jogalkotó szervek próbálják kialakítani a megfelelő szabályozást eme égető kérdésre. Ezen téma nem ismeretlen számomra. Tudományos diákköri dolgozatomat a Dark Web anomáliájáról írtam, ezt tovább vittem szakdolgozatomba, ahol pedig is a kiberbűnözés jelenségét vizsgáltam a nemzetközi porondon.

Kutatásomban azt vizsgáltam, hogyan lehetséges, hogy 2021-ben nincs egy egységes nemzetközi kiberbiztonsági egyezmény. Ennek több oka is van: kényes kérdés-ugyanis összefügg az állami külpolitikával; fogalmi bizonytalanságok-a jelenlegi jogtudományi álláspont sem egységes bizonyos kérdésekben; jogalanyok eltérő gyakorlata-az egyes államok valamint IGO-k gyakorlata eltérő;túlszabályozottság-jelenleg olyan sok egyezmény, szervezet foglalkozik a kérdéssel, hogy már már átláthatatlan a téma.
„Egészen uj csődosztályzati projectum”
Authors: Pétervári Máté
Published: February 2022

Az 1848-49. évi szabadságharc bukása után a neoabszolutizmus jelentősen átalakította a magyar jogrendszert, mivel az Osztrák Császárság jogi egységesítése céljából az osztrák törvénykönyvek bevezetésére került sor. Ferenc József az Októberi Diploma kiadásával enyhített a korábbi abszolút kormányzati felfogáson, valamint visszaállította az 1847 előtti magyar közigazgatási és törvénykezési szervezetet. Ennek keresztülvitelével az újonnan kinevezett országbírót, gr. Apponyi Györgyöt bízta meg, aki ebből a célból egy tanácskozást hívott össze. Ez a gyűlés a magyar történetírásba Országbírói Értekezlet néven vonult be, amely rendelkezett a magyar bíróságokon alkalmazandó joganyagról.

Jelen tanulmányban ezen tanácskozás csődjogra gyakorolt hatását vizsgálom, amelynek keretében bemutatom az Országbírói Értekezlet e jogterületre vonatkozó rendelkezéseit és a gyűlésen készült jegyzőkönyv alapján a szabályozás „mozgatórugóit”. Az osztrák ideiglenes csődrendtartás helyett ugyanis ismételten hatályba léptették az első magyar csődtörvényt, az 1840:22. tc.-et. A szakirodalomban ennek kapcsán jellemzően csupán az jelenik meg, hogy az Országbírói Értekezlet a polgári korszak változásaihoz idomította a törvénycikk anyagi és alaki szabályait. A tanácskozás résztvevői által kifejtett álláspontok és levéltári források ismertetésével szemléltetem, hogy a módosítások ennél komolyabb változásokat generáltak. Emellett a csődönkívüli kényszeregyezség első magyarországi megjelenése is a neoabszolutizmus korszakához kapcsolódott, amelyre szintén reagált a magyar jogtudomány színe-javát felvonultató értekezlet.