bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Methods, Figures 1 - 13 from A Macrophage-Specific Fluorescent Probe for Intraoperative Lymph Node Staging
Authors: Yoo Jung Sun , Lee Sung-Chan , Jow Zhi Yen , Koh Pamela Yun Xiang , Chang Young-Tae
Published: April 2023

PDF file - 5664K, Supplementary Figure 1: Overview of high-throughput screening, Supplementary Figure 2: Synthesis scheme for MFP, Supplementary Figure 3: Identification spectra of MFP obtained by using 1H-NMR and 13C-NMR, Supplementary Figure 4: Identification LC-MS spectrum of MFP, Supplementary Figure 5: Physiochemical properties of MFP, Supplementary Figure 6: Macrophage differentiation with the U-937 cell line by using PMA stimulation, Supplementary Figure 7: Selective macrophage staining with MFP for different concentrations and incubation times, Supplementary Figure 8: Effect of MFP on cell viability, Supplementary Figure 9: Enrichment of T lymphocytes, monocytes and granulocytes from human blood, Supplementary Figure 10: Macrophage differentiation with peripheral blood monocytes, Supplementary Figure 11: Characterization of MFP+ cells in inflamed lymph nodes, Supplementary Figure 12: Characterization of MFP+ cells in metastatic lymph nodes, Supplementary Figure 13: Structural selectivity test with several analogues of MFP, Supplementary Methods.
Supplementary Figure 6 from Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth
Authors: Barceló Carles , Paco Noelia , Morell Mireia , Alvarez-Moya Blanca , Bota-Rabassedas Neus , Jaumot Montserrat , Vilardell Felip , Capella Gabriel , Agell Neus
Published: April 2023

PDF file - 27K, Figure S6. Detection of the phosphorylated form of oncogenic KRAS in human pancreatic ductal adenocarcinoma by 2-DE.
Supplementary Figure 1 from CD133+ Cancer Stem-like Cells in Small Cell Lung Cancer Are Highly Tumorigenic and Chemoresistant but Sensitive to a Novel Neuropeptide Antagonist
Authors: Sarvi Sana , Mackinnon Alison C. , Avlonitis Nicolaos , Bradley Mark , Rintoul Robert C. , Rassl Doris M. , Wang Wei , Forbes Stuart J. , Gregory Christopher D. , Sethi Tariq
Published: April 2023

PDF file - 519KB, Apoptosis in etoposide treated H345 cells and etoposide treated mouse tumors immunostained for CD133 and GRP-R.
Supplementary Figure 1 from Bcl2 Induces DNA Replication Stress by Inhibiting Ribonucleotide Reductase
Authors: Xie Maohua , Yen Yun , Owonikoko Taofeek K. , Ramalingam Suresh S. , Khuri Fadlo R. , Curran Walter J. , Doetsch Paul W. , Deng Xingming
Published: April 2023

PDF file - 111K, Bcl2 downregulates intracellular dNTPs via inhibition of RNR activity.
Data Supplement from Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC
Authors: Tchaicha Jeremy H. , Akbay Esra A. , Altabef Abigail , Mikse Oliver R. , Kikuchi Eiki , Rhee Kevin , Liao Rachel G. , Bronson Roderick T. , Sholl Lynette M. , Meyerson Matthew , Hammerman Peter S. , Wong Kwok-Kin
Published: April 2023

Supplemental Figure 2. FGFR2/CC10 staining of 20 and 32 week FGFR2 lung tumors.
Data Supplement from Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC
Authors: Tchaicha Jeremy H. , Akbay Esra A. , Altabef Abigail , Mikse Oliver R. , Kikuchi Eiki , Rhee Kevin , Liao Rachel G. , Bronson Roderick T. , Sholl Lynette M. , Meyerson Matthew , Hammerman Peter S. , Wong Kwok-Kin
Published: April 2023

Supplemental Figure 4. Brain lesions that arise after metastasis from the nasal epithelium.
Supplementary Figure 3 from Critical Tumor Suppressor Function Mediated by Epithelial Mig-6 in Endometrial Cancer
Authors: Kim Tae Hoon , Lee Dong-Kee , Cho Sung-Nam , Orvis Grant D. , Behringer Richard R. , Lydon John P. , Ku Bon Jeong , McCampbell Adrienne S. , Broaddus Russell R. , Jeong Jae-Wook
Published: April 2023

PDF file - 249K, Expression of PR protein and its target genes in Wnt7acre+ Mig-6f/f mice after P4 treatment.
Supplementary Methods and Figure Legends from Invasive Lobular Carcinoma Cell Lines Are Characterized by Unique Estrogen-Mediated Gene Expression Patterns and Altered Tamoxifen Response
Authors: Sikora Matthew J. , Cooper Kristine L. , Bahreini Amir , Luthra Soumya , Wang Guoying , Chandran Uma R. , Davidson Nancy E. , Dabbs David J. , Welm Alana L. , Oesterreich Steffi
Published: April 2023

PDF file - 137K
Supplementary Tables 1 - 4 from Identification of Alternative Splicing Events Regulated by the Oncogenic Factor SRSF1 in Lung Cancer
Authors: de Miguel Fernando J. , Sharma Ravi D. , Pajares María J. , Montuenga Luis M. , Rubio Angel , Pio Ruben
Published: April 2023

PDF file - 54K, Supplementary Table S1. Characteristics of microarray platforms for the analysis of splicing. Supplementary Table S2. Clinicopathological characteristics of the patients. Supplementary Table S3. List of the top 20 ranked genes selected by ExonPointer from the expression data obtained using Oryzon arrays. Supplementary Table S4. Results of the ExonPointer analysis in genes reported by Karni et al. (2007) as targets of SRSF1.
Supplementary Methods from HO-3867, a Safe STAT3 Inhibitor, Is Selectively Cytotoxic to Ovarian Cancer
Authors: Rath Kellie S. , Naidu Shan K. , Lata Pushpa , Bid Hemant K. , Rivera Brian K. , McCann Georgia A. , Tierney Brent J. , ElNaggar Adam C. , Bravo Veronica , Leone Gustavo , Houghton Peter , Hideg Kálmán , Kuppusamy Periannan , Cohn David E. , Selvendiran Karuppaiyah
Published: April 2023

PDF file - 146K, Methods for HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer.
Supplementary Materials and Methods and Supplementary Figure Legends from Accumulation of Cytosolic Calcium Induces Necroptotic Cell Death in Human Neuroblastoma
Authors: Nomura Motonari , Ueno Ayumi , Saga Kotaro , Fukuzawa Masahiro , Kaneda Yasufumi
Published: April 2023

PDF - 142K, This file contains Supplementary Materials and Methods and Supplementary Figure Legends for Figures S1 to S11.
Supplementary Figure 7 from Accumulation of Cytosolic Calcium Induces Necroptotic Cell Death in Human Neuroblastoma
Authors: Nomura Motonari , Ueno Ayumi , Saga Kotaro , Fukuzawa Masahiro , Kaneda Yasufumi
Published: April 2023

PDF - 51K, HVJ-E-induced cell death in SK-N-SH cells is not mediated by PKC.
Supplementary Figure 10 from Accumulation of Cytosolic Calcium Induces Necroptotic Cell Death in Human Neuroblastoma
Authors: Nomura Motonari , Ueno Ayumi , Saga Kotaro , Fukuzawa Masahiro , Kaneda Yasufumi
Published: April 2023

PDF - 116K, HVJ-E induces necroptosis in xenograft tumors derived from SK-N-SH cells.
Supplementary Figure 4 from Activation of the FGFR–STAT3 Pathway in Breast Cancer Cells Induces a Hyaluronan-Rich Microenvironment That Licenses Tumor Formation
Authors: Bohrer Laura R. , Chuntova Pavlina , Bade Lindsey K. , Beadnell Thomas C. , Leon Ronald P. , Brady Nicholas J. , Ryu Yungil , Goldberg Jodi E. , Schmechel Stephen C. , Koopmeiners Joseph S. , McCarthy James B. , Schwertfeger Kathryn L.
Published: April 2023

PDF file - 116K, Supplemental Figure 4. Activation of FGFR (1) leads to increased gene expression and secretion of IL-6 family members (2). These bind to the gp130 receptor (3) which activates STAT3 (4). Phosphorylated STAT3 regulates HAS2 expression (5). HAS2 stimulates production of hyaluronan (6), which is then secreted and contributes to induced proliferation, migration and chemoresistance.
Supplementary Figure 11 from Mechanistic Elucidation of the Antitumor Properties of Withaferin A in Breast Cancer
Authors: Nagalingam Arumugam , Kuppusamy Panjamurthy , Singh Shivendra V. , Sharma Dipali , Saxena Neeraj K.
Published: April 2023

PDF file - 80KB, Supplementary Figure 11 WFA is a potent inducer of Death receptor 5 in breast cancer cells.
Supplementary Figure Legend from Role of Chitinase 3–like-1 and Semaphorin 7a in Pulmonary Melanoma Metastasis
Authors: Ma Bing , Herzog Erica L. , Lee Chun Geun , Peng Xueyan , Lee Chang-Min , Chen Xiaosong , Rockwell Sara , Koo Ja Seok , Kluger Harriet , Herbst Roy S. , Sznol Mario , Elias Jack A.
Published: April 2023

Supplementary Figure Legend
Supplemental Table 1 and 2 and Supplemental Figure 1-5. from Activin Upregulation by NF-κB Is Required to Maintain Mesenchymal Features of Cancer Stem–like Cells in Non–Small Cell Lung Cancer
Authors: Wamsley J. Jacob , Kumar Manish , Allison David F. , Clift Sheena H. , Holzknecht Caitlyn M. , Szymura Szymon J. , Hoang Stephen A. , Xu Xiaojiang , Moskaluk Christopher A. , Jones David R. , Bekiranov Stefan , Mayo Marty W.
Published: April 2023

Supplemental Table 1 and 2 and Supplemental Figure 1-5. Supplemental Table 1: Oligonucleotide sequences of shRNA molecules targeting INHBA/Activin and the targeted sequences. Supplemental Table 2: Oligonucleotide sequences used for amplification in QRTPCR. Supplemental Figure 1: Microarray analysis performed on mesenchymal A549 cells show massive and reproducible epigenetic changes in gene expression without upregulating TGFβ or NODAL. Supplemental Figure 2: Mesechymal NSCLC cells are capable of sustaining INHBA upregulation over a four-day time course. Supplemental Figure 3: The ability of condition media to stimulate SNAI1 transcription is blocked by the ALK4/ALK5/ALK7 inhibitor. Supplemental Figure 4: Infection of A549 cells with shRNA targeting INHBA. Supplemental Figure 5: Representative images of transwell assay inserts.
Figure S5. ChIP-seq analysis of FLAG-H1.3 in OV-3/H1.3(H) cells. from Histone H1.3 Suppresses H19 Noncoding RNA Expression and Cell Growth of Ovarian Cancer Cells
Authors: Medrzycki Magdalena , Zhang Yunzhe , Zhang Weijia , Cao Kaixiang , Pan Chenyi , Lailler Nathalie , McDonald John F. , Bouhassira Eric E. , Fan Yuhong
Published: April 2023

Figure S5. ChIP-seq analysis of FLAG-H1.3 in OV-3/H1.3(H) cells. A) Metagene analysis of H1.3 distribution on genes partitioned by gene expression levels (each group containing 20% of genes in genome) over a 10 kb region covering -5 kb to +5 kb of transcription start sites (TSS). On average, H1.3 exhibits the deepest dip at TSS of highly expressed genes (red) but no or minimal dip at TSS of inactive genes (blue). ChIP-seq was performed using anti-FLAG antibody in OV-3/H1.3(H) cells. B) Distribution of H1.3 along H19 (upper) and GAPDH (lower) loci in OV-3/H1.3(H) cells. Y axis: tag counts per 1000 bp window per 10 million mappable reads. IP-IN: normalized signal intensity of ChIP-seq subtracted by that of input-seq.
Supplementary Figure Legends from Astrocyte Elevated Gene-1 Interacts with Akt Isoform 2 to Control Glioma Growth, Survival, and Pathogenesis
Authors: Hu Bin , Emdad Luni , Bacolod Manny D. , Kegelman Timothy P. , Shen Xue-Ning , Alzubi Mohammad A. , Das Swadesh K. , Sarkar Devanand , Fisher Paul B.
Published: April 2023

Supplementary Figures Legends S1-S9.
Supplementary Methods, Figures 1 - 8, Tables 1 - 2 from VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation
Authors: Fantozzi Anna , Gruber Dorothea C. , Pisarsky Laura , Heck Chantal , Kunita Akiko , Yilmaz Mahmut , Meyer-Schaller Nathalie , Cornille Karen , Hopfer Ulrike , Bentires-Alj Mohamed , Christofori Gerhard
Published: April 2023

PDF file - 7604K, Supplemental Figure S1 depicts the increased sensitivity of mesenchymal MTdeltaECad cells to salinomycin as compared to epithelial MTflECad cells. Supplemental Figure S2 shows comparable numbers of mesenchymal MTdeltaECad cells and epithelial MTflECad cells injected i.v. trapped in in lungs and no difference in cell proliferation but higher apoptosis of epithelial MTflECad cells in lung outgrowing lung metastasis. Supplemental Figure S3 presents the assessment of VEGF receptor expression, blood vessel maturation and functionality, and tumor cell proliferation and apoptosis in primary tumors formed by mesenchymal MTdeltaECad cells as compared to tumors of epithelial MTflECad cells. Supplemental Figure S4 shows the upregulated expression of pro-angiogenic genes during EMT by gene ontology and direct gene expression analysis. Supplemental Figure S5 shows an efficient siRNA-mediated ablation of VEGF-A expression in mesenchymal MTdeltaECad cells and that the ablation of VEGF-A expression, treatment with the VEGF receptor inhibitor PTK787 or the addition of recombinant VEGF-A do not affect cell proliferation and mammosphere growth of MTdeltaECad cells or MTflECad cells. Supplemental Figure S6 shows that the forced expression of VEGF-A in epithelial MTflECad cells modestly increases the cells' tumorigenicity and significantly induces tumor microvessel density and vessel functionality, it reduces apoptosis but does not affect tumor hypoxia and cell proliferation. Supplemental Figure S7 shows that other VEGF family members are upregulated in their expression during an EMT in vitro and in vivo, yet that they do not affect tumorigenicity of mesenchymal cancer cells. Supplemental Figure S8 demonstrates that VEGF-A in the supernatant of cultured mesenchymal MTdeltaECad cells induces proliferation of human umbilical vein endothelial cells (HUVEC). Supplemental Table I summarizes the flow cytometry analysis of cell surface markers in NMuMG normal murine mammary gland cell line and in the Py2T and MTflECad/MTdeltaECad murine breast cancer cell lines before and after EMT and cultured on plastic or as spheroids. Supplemental Table II presents the differences in cytokine expression between epithelial MTflECad cells and mesenchymal MTdeltaECad cells as determined by cytokine protein array analysis. Supplemental Methods provide experimental details of the general experimental procedures and reagents used in the main text and of the specific methods used to generate the supplemental data.
Supplementary Video 2 from VEGF Regulates Region-Specific Localization of Perivascular Bone Marrow–Derived Cells in Glioblastoma
Authors: Burrell Kelly , Singh Sanjay , Jalali Shahrzad , Hill Richard P. , Zadeh Gelareh
Published: April 2023

MOV file - 2797KB, Z-Stack images capturing a 150microm depth section of the window every 10microm demonstrates the ability of the imaging to enhance the three dimensional morphology of BMDCs and their relationship to the vessels.
Supplementary Figure Legends from VEGF-Targeted Therapy Stably Modulates the Glycolytic Phenotype of Tumor Cells
Authors: Curtarello Matteo , Zulato Elisabetta , Nardo Giorgia , Valtorta Silvia , Guzzo Giulia , Rossi Elisabetta , Esposito Giovanni , Msaki Aichi , Pastò Anna , Rasola Andrea , Persano Luca , Ciccarese Francesco , Bertorelle Roberta , Todde Sergio , Plebani Mario , Schroer Henrike , Walenta Stefan , Mueller-Klieser Wolfgang , Amadori Alberto , Moresco Rosa Maria , Indraccolo Stefano
Published: April 2023

Supplementary Figure Legends. Legends for Supplementary Figures S1-S9.
Data Supplement from Mitochondrial Retrograde Signaling Mediated by UCP2 Inhibits Cancer Cell Proliferation and Tumorigenesis
Authors: Esteves Pauline , Pecqueur Claire , Ransy Céline , Esnous Catherine , Lenoir Véronique , Bouillaud Frédéric , Bulteau Anne-Laure , Lombès Anne , Prip-Buus Carina , Ricquier Daniel , Alves-Guerra Marie-Clotilde
Published: April 2023

Supplementary figure legends
Data Supplement from Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression
Authors: Jeon Hye-Min , Kim Sung-Hak , Jin Xun , Park Jong Bae , Kim Se Hoon , Joshi Kaushal , Nakano Ichiro , Kim Hyunggee
Published: April 2023

Supplementary Table S1. Nucleotide sequences (5' to 3').
Supplementary Table 1 from TGF-β Modulates Ovarian Cancer Invasion by Upregulating CAF-Derived Versican in the Tumor Microenvironment
Authors: Yeung Tsz-Lun , Leung Cecilia S. , Wong Kwong-Kwok , Samimi Goli , Thompson Melissa S. , Liu Jinsong , Zaid Tarrik M. , Ghosh Sue , Birrer Michael J. , Mok Samuel C.
Published: April 2023

PDF file, 130K, TGF-B concentrations in conditioned media of the co-culture system.
Table S3 from USP9X Downregulation Renders Breast Cancer Cells Resistant to Tamoxifen
Authors: Oosterkamp Hendrika M. , Hijmans E. Marielle , Brummelkamp Thijn R. , Canisius Sander , Wessels Lodewyk F.A. , Zwart Wilbert , Bernards René
Published: April 2023

Patient and tumor characteristics of patients with ERa positive breast cancers
Supplementary Methods and Figures 1 - 9 from Axon Guidance Factor SLIT2 Inhibits Neural Invasion and Metastasis in Pancreatic Cancer
Authors: Göhrig Andreas , Detjen Katharina M. , Hilfenhaus Georg , Körner Jan L. , Welzel Martina , Arsenic Ruza , Schmuck Rosa , Bahra Marcus , Wu Jane Y. , Wiedenmann Bertram , Fischer Christian
Published: April 2023

PDF file - 643KB, Figure S1: Reactivation of Slit2 expression in Panc1 cells by 5-AZA-dC suggests silencing of Slit2 gene due to promoter hypermethylation. Figure S2: Slit2 inhibits directed migration of pancreatic tumor cells. Figure S3: Re-expression of Slit2 does not affect random migration of MiaPaCaTR-Slit2 Cells. Figure S4: Doxycycline treatment results in induction of Slit2 protein in MiaPaCaTR-Slit2 tumors in vivo. Figure S5: Inducible re-expression of Slit2 inhibits invasion, metastasis and angiogenesis in size-matched orthotopic pancreatic tumors. Figure S6: Stable knock down of Robo1 in pancreatic tumor cells promotes metastasis, but does not affect angiogenesis of orthotopic pancreatic tumors. Figure S7: Functional inhibition of Slit2 via Robo1-Fc stimulates angiogenesis in DANGRobo1-KD tumors subjected to Robo1 receptor knock down. Figure S8: Forced expression of Slit2 inhibits metastasis and invasion in the orthotopic Panc02 syngeneic tumor model. Figure S9: Time-lapse microscopy reveals directional navigation of tumor cells along Neuritis.
Table S2 from USP9X Downregulation Renders Breast Cancer Cells Resistant to Tamoxifen
Authors: Oosterkamp Hendrika M. , Hijmans E. Marielle , Brummelkamp Thijn R. , Canisius Sander , Wessels Lodewyk F.A. , Zwart Wilbert , Bernards René
Published: April 2023

Directionality of USP9XKD-tamoxifen classification genes
Table S1 from USP9X Downregulation Renders Breast Cancer Cells Resistant to Tamoxifen
Authors: Oosterkamp Hendrika M. , Hijmans E. Marielle , Brummelkamp Thijn R. , Canisius Sander , Wessels Lodewyk F.A. , Zwart Wilbert , Bernards René
Published: April 2023

ChIP-seq read counts, aligned reads and peak numbers
Supplementary Figure S5 from USP9X Downregulation Renders Breast Cancer Cells Resistant to Tamoxifen
Authors: Oosterkamp Hendrika M. , Hijmans E. Marielle , Brummelkamp Thijn R. , Canisius Sander , Wessels Lodewyk F.A. , Zwart Wilbert , Bernards René
Published: April 2023

Figure S5. Survival analysis for 1874 shUSP9X-affected genes not associated with estrogen induction. (A) The 1874 shUSP9X-affected genes, not associated with E2-treatment (see Fig. 5A), were tested as a classifier in two cohorts of ERÃŽÂ± positive breast cancer patients who received adjuvant tamoxifen treatment (Loi: n=250; Buffa: n=134) (35, 36). Kaplan-Meier survival curves for distant metastasis free survival (DMFS) were generated, with p values indicated. (B) Hazard rates with 95% confidence intervals, separately analyzing the Loi cohort (left) and Buffa cohort (right). The USP9X knockdown tamoxifen classifier was directly compared with the 1874 genes that were differentially expressed after shUSP9X, but not affected by E2 stimulation (see Figure 5A).
Supplementary Figrue S3 from USP9X Downregulation Renders Breast Cancer Cells Resistant to Tamoxifen
Authors: Oosterkamp Hendrika M. , Hijmans E. Marielle , Brummelkamp Thijn R. , Canisius Sander , Wessels Lodewyk F.A. , Zwart Wilbert , Bernards René
Published: April 2023

Figure S3. Heatmap and quantifications for subsets of ChIP-seq data. (A) Heatmap visualization of ERÃŽÂ± chromatin binding events in shGFP cells, separately analyzing binding sites shared or unique for vehicle, E2 or 4-OHT conditions, as indicated in Figure 4C. All peaks were vertically aligned and centered on the top of the peak, with a window of 5 kb. Number of binding sites for each subgroup are shown. (B) Quantifications of read count at ERÃŽÂ± chromatin binding sites for different subgroups of chromatin as shown in A, with a 2.5 kb window. Y-axis shows average tag count. (C) Heatmap visualization of ERÃŽÂ± chromatin binding events in shUSP9X cells, separately analyzing binding sites shared or unique for vehicle, E2 or 4-OHT conditions, as indicated in Figure 4C. All peaks were vertically aligned and centered on the top of the peak, with a window of 5 kb. (D) Quantifications of read count at ERÃŽÂ± chromatin binding sites for different subgroups of chromatin as shown in C, with a 2.5 kb window. Y-axis shows average tag count.
Supplementary Figure 5 from BRCA2 Phosphorylated by PLK1 Moves to the Midbody to Regulate Cytokinesis Mediated by Nonmuscle Myosin IIC
Authors: Takaoka Miho , Saito Hiroko , Takenaka Katsuya , Miki Yoshio , Nakanishi Akira
Published: April 2023

PDF file - 106K, Abnormal midbody and binucleated cells induced by expression of NM-IIC (A1) or BRCA2 (R1) (Related to Figure 4).
Supplementary Figure 3 from BRCA2 Phosphorylated by PLK1 Moves to the Midbody to Regulate Cytokinesis Mediated by Nonmuscle Myosin IIC
Authors: Takaoka Miho , Saito Hiroko , Takenaka Katsuya , Miki Yoshio , Nakanishi Akira
Published: April 2023

PDF file - 201K, Abnormal cytokinesis following BRCA2 or NM-IIC gene silencing (Related to Figure 3).
Supplementary Figures 1 - 5 from IRP2 Regulates Breast Tumor Growth
Authors: Wang Wei , Deng Zhiyong , Hatcher Heather , Miller Lance D. , Di Xiumin , Tesfay Lia , Sui Guangchao , D'Agostino Ralph B. , Torti Frank M. , Torti Suzy V.
Published: April 2023

PDF file - 514K, Supplemental Figures 1-5. Supplemental Fig 1: IRP2, TfR1 and Ferritin H transcript levels in a series of breast cancer cell lines examined by real-time qPCR. Supplemental Fig 2. IRP2, TfR1 and Ferritin H transcript levels in IRP2 knockdown MDA-MB-231 cells. Supplemental Fig 3. Growth of MCF7 cells following IRP2 knockdown. Supplemental Fig 4. IRP2 overexpression is not sufficient to increase proliferation of MCF10A cells. Supplemental Fig 5. Bioluminescent images of tumor xenografts on day 32.
Supplementary Table 1 from Extracellular RNA Liberates Tumor Necrosis Factor-α to Promote Tumor Cell Trafficking and Progression
Authors: Fischer Silvia , Gesierich Sabine , Griemert Barbara , Schänzer Anne , Acker Till , Augustin Hellmut G. , Olsson Anna-Karin , Preissner Klaus T.
Published: April 2023

PDF-64K, Number of seeded living and transmigrated tumor cells.
Supplementary Table 4 from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: April 2023

PDF file - 27KB, Comparison of positions for YAP phosphorylation sites in different YAP isoforms.
Supplementary Table 3 from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: April 2023

PDF file - 52KB, Antibodies used in present study.
Supplementary Figure Legends from YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Authors: Zhao Yulei , Khanal Prem , Savage Paul , She Yi-Min , Cyr Terry D. , Yang Xiaolong
Published: April 2023

PDF file - 69KB
Supplementary Movie 4 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: April 2023

AVI file - 749KB, Dynamics of ARv7 variant nuclear accumulation in untreated cells.
Supplementary Figure 3 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: April 2023

PDF file - 182KB, R1881 treatment in M12 cells transfected with ARv567 and ARv7 does not increase AR-variant nuclear accumulation.
Supplementary Figure 1 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: April 2023

PDF file - 112KB, Microtubule co-sedimentation assay in a different cell line confirms that the C-ter of AR mediates association with microtubules.
Supplementary Figure 4 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: April 2023

PDF file - 2499K, A, Western blot analyses showing expression of AZIN1 protein in the indicated cell lines. β-actin was the loading control. B, Quantification of cells from the indicated cells that migrated through the PET-membrane or invaded through the Matrigel-coated membrane.
Supplemental Tables S1-S2 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: April 2023

IHC scores of ADAR1 in 136 matched pairs of primary ESCCs and (NT) tissues (S1); The positive correlation between the tumoral overexpression of ADAR1 and tumoral genomic amplification of ADAR1 (S2).
Supplemental Methods and Reference from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: April 2023

Description of additional methods and procedures used in the study. Also includes supplemental reference.
Supplemental Figure S3 from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: April 2023

The total mRNA levels of AZIN1 (left panel) and FLNB (right panel) in 69 matched pairs of ESCC and NT specimens in Cohort 1 (Paired Student's t test).
Supplementary Figure 8 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: April 2023

PDF file - 143K, Un-cropped immunoblot images. Original images used to generate panels in Figures 1, 2, 3, 4, and 5.
Supplementary Figure 1 from Activation of the Glutamate Receptor GRM1 Enhances Angiogenic Signaling to Drive Melanoma Progression
Authors: Wen Yu , Li Jiadong , Koo Jasmine , Shin Seung-Shick , Lin Yong , Jeong Byeong-Seon , Mehnert Janice M. , Chen Suzie , Cohen-Sola Karine A. , Goydos James S.
Published: April 2023

PDF file - 737KB, Supplemental Figure 1: Apoptosis antibody array result of Uacc903-V1 and -G2.
Supplementary Figure 3 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: April 2023

PDF file - 114K, ICAT DQE mutant does not bind to b-catenin.
Supplementary Figure 1 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: April 2023

PDF file - 129K, IF staining of ICAT and b-catenin in melanoma cells.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure 3:Subcutaneous implantation of MCF10AT1 cells.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure 5: Histological evaluation.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure 6: Decreased tumor development by Hpa-Tg mice treated with PG545, a heparanase inhibitor.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure 7: DMBA or TPA as single agent do not elicit tumor formation in control and Hpa-Tg mice.
Supplementary Figure S6 from Myostatin Gene Inactivation Prevents Skeletal Muscle Wasting in Cancer
Authors: Gallot Yann S. , Durieux Anne-Cécile , Castells Josiane , Desgeorges Marine M. , Vernus Barbara , Plantureux Léa , Rémond Didier , Jahnke Vanessa E. , Lefai Etienne , Dardevet Dominique , Nemoz Georges , Schaeffer Laurent , Bonnieu Anne , Freyssenet Damien G.
Published: April 2023

Serum levels of interferon (IFN)-γ, interleukin (IL)-1β, IL-6 and tumor necrosis (TNF)-α in wild-type (n=7) and Mstn-/- mice (n=8).
Supplementary Figures S1-S12 from Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma
Authors: Gopal Y.N. Vashisht , Rizos Helen , Chen Guo , Deng Wanleng , Frederick Dennie T. , Cooper Zachary A. , Scolyer Richard A. , Pupo Gulietta , Komurov Kakajan , Sehgal Vasudha , Zhang Jiexin , Patel Lalit , Pereira Cristiano G. , Broom Bradley M. , Mills Gordon B. , Ram Prahlad , Smith Paul D. , Wargo Jennifer A. , Long Georgina V. , Davies Michael A.
Published: April 2023

Supplementary Figures S1-S12. Figure S1. Ingenuity Pathway Analysis (IPA) and Netwalker analysis of the PLX4720-synthetic lethal genes. Figure S2. Effect of Selumetinib on the mitochondrial gene expression in high OxPhos MEL624 cell lines. Figure S3. Differential energy consumption and release in selumetinib-sensitive and resistant melanoma cell lines. Figure S4. Oxygen consumption in MEKi+mTORC1/2i combination-resistant and Ã¢??sensitive melanoma cell lines. Figure S5. Cellular effects of FDA approved single agent MEK and BRAF inhibitors Trametinib and Dabrafenib and their combinations with AZD8055. Figure S6. RPPA proteomic analysis of protein lysates from three combination-resistant (1) and three Ã¢??sensitive (2) BRAF mutant melanoma cell lines following MEK or mTORC1/2 inhibition. Figure S7. Correlation of MITF expression with selumetinib and AZD8055 combination synergy in 14 melanoma cell lines. Figure S8. Effect of selumetinib and AZD8055 on the cellular localization of MITF and consequence of MITF knockdown Figure S9. Comparative effects of AZD8055 and AZD2014. Figure S10. Drug concentration against percentage of cell growth inhibition. Figure S11. The proliferation of the A375, its resistant clones Ã¢??R1 and -R2, and WM35 and its resistant clones in presence of increasing concentrations of selumetinib, AZD8055 and their combination after 72 h treatment was determined as described in Figure S8. Figure S12. A) Ratio of PGC1ÃŽÂ± and MITF gene expression at the time of disease progression versus pre-treatment in the MGH cohort of patients treated with single-agent vemurafenib (MGH-25) or with dabrafenib + trametinib (all others). B) PGC1ÃŽÂ± expression in 917 cell lines of the Cancer Cell Line Encyclopedia (CCLE) representing 23 cancer types.
Supplementary Table 1 from BRG1/SMARCA4 Inactivation Promotes Non–Small Cell Lung Cancer Aggressiveness by Altering Chromatin Organization
Authors: Orvis Tess , Hepperla Austin , Walter Vonn , Song Shujie , Simon Jeremy , Parker Joel , Wilkerson Matthew D. , Desai Nisarg , Major Michael B. , Hayes D. Neil , Davis Ian J. , Weissman Bernard
Published: April 2023

Supplementary Table 1. Differentially expressed genes were identified, as described in Material and Methods. Genes altered by BRG1 KD- Genes whose expression either increased or decreased in the H358 Brg1i.1 and H358 Brgi.2 cell lines; Upregulated and unregulated genes- We identified 316 genes that showed increased expression in both H358 Brg1i.1 and H358 Brg1i.2 cell lines. We also identified 300 genes that did not show altered expression in the Brg1i.2 cell line.
Supplementary Figure 1 from BRG1/SMARCA4 Inactivation Promotes Non–Small Cell Lung Cancer Aggressiveness by Altering Chromatin Organization
Authors: Orvis Tess , Hepperla Austin , Walter Vonn , Song Shujie , Simon Jeremy , Parker Joel , Wilkerson Matthew D. , Desai Nisarg , Major Michael B. , Hayes D. Neil , Davis Ian J. , Weissman Bernard
Published: April 2023

Supplementary Figure 1. This figure shows validation of H358 and H441 Brg1 knockdown cell lines.
Data Supplement from IL4 Receptor ILR4α Regulates Metastatic Colonization by Mammary Tumors through Multiple Signaling Pathways
Authors: Venmar Katherine T. , Carter Kathy J. , Hwang Daniel G. , Dozier E. Ashley , Fingleton Barbara
Published: April 2023

Supplemental Figure 2: Immunohistochemical analysis of survival and proliferation in lung and liver metastases
Data Supplement from IL4 Receptor ILR4α Regulates Metastatic Colonization by Mammary Tumors through Multiple Signaling Pathways
Authors: Venmar Katherine T. , Carter Kathy J. , Hwang Daniel G. , Dozier E. Ashley , Fingleton Barbara
Published: April 2023

Supplemental Figure 3: Immunohistochemical staining of immune infiltrates in R221a lung metastases
Data Supplement from IL4 Receptor ILR4α Regulates Metastatic Colonization by Mammary Tumors through Multiple Signaling Pathways
Authors: Venmar Katherine T. , Carter Kathy J. , Hwang Daniel G. , Dozier E. Ashley , Fingleton Barbara
Published: April 2023

Supplemental Figure 4: Immunohistochemical staining of immune infiltrates in 4T1 metastases
Supplementary Figure S7 from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: April 2023

Supplemental Figures 7A,B: True color images and TPP[cy5.5]-derived fluorescence signals of tumor-bearing mice. Figure S7A: dorsal views of CT26 Tumors (s.c.). Figure 7B: ventral views of 4T1 tumors (o.t.)in mice.
Supplementary Table 1 from RAGE Expression in Tumor-Associated Macrophages Promotes Angiogenesis in Glioma
Authors: Chen Xuebo , Zhang Leying , Zhang Ian Y. , Liang Junling , Wang Huaqing , Ouyang Mao , Wu Shihua , da Fonseca Anna Carolina Carvalho , Weng Lihong , Yamamoto Yasuhiko , Yamamoto Hiroshi , Natarajan Rama , Badie Behnam
Published: April 2023

Supplementary Table 1: Primers used in the real-time quantitative PCR.
Supplementary Methods from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: April 2023

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Supplementary Figure Legend, Tables 1 - 2 from Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H2O2 Generation
Authors: Rawal Malvika , Schroeder Samuel R. , Wagner Brett A. , Cushing Cameron M. , Welsh Jessemae L. , Button Anna M. , Du Juan , Sibenaller Zita A. , Buettner Garry R. , Cullen Joseph J.
Published: April 2023

PDF file - 102K, Table 1. AscH- and MnT4MPyP are synergistic as seen by Combination Index (CI) and Dose Reduction Index (DRI). Table 2. Summary statistics for tumor volume measurements in the generalized estimating equations analysis.
Supplementary Figure Legends from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: April 2023

PDF file - 78K
Supplementary Table 3 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: April 2023

PDF file - 41K, Distribution of lymphoma samples into "Ongoing" or "Static" categories based on the proportion of IGHV subclones that are identical at the CDR3 region for each sample.
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: April 2023

Supplementary Table S6. Supplementary data for differentially expressed genes between canine ER+ and ER- carcinomas, including the gene list and enriched functions among the genes.
Supplementary Figure Legend from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: April 2023

PDF file - 60K
Supplementary Figure 3 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: April 2023

PDF file - 881K, Western blot comparing phospho-NF-κB (p65) levels in "ABC-like" and "GCB-like" canine samples.
Supplementary Figure 2 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: April 2023

PDF file - 843K, Unsupervised hierarchical clustering of cBCLs.
Supplemental Movie S1 from Novel Paracrine Modulation of Notch–DLL4 Signaling by Fibulin-3 Promotes Angiogenesis in High-Grade Gliomas
Authors: Nandhu Mohan S. , Hu Bin , Cole Susan E. , Erdreich-Epstein Anat , Rodriguez-Gil Diego J. , Viapiano Mariano S.
Published: April 2023

Animation of 3D confocal rendering related to Figure 3E.
Supplementary Table 2 from Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties
Authors: Ostenfeld Marie Stampe , Jeppesen Dennis K. , Laurberg Jens R. , Boysen Anders T. , Bramsen Jesper B. , Primdal-Bengtson Bjarke , Hendrix An , Lamy Philippe , Dagnaes-Hansen Frederik , Rasmussen Mads H. , Bui Khan H. , Fristrup Niels , Christensen Erik I. , Nordentoft Iver , Morth Jens P. , Jensen Jørgen B. , Pedersen Jakob S. , Beck Martin , Theodorescu Dan , Borre Michael , Howard Kenneth A. , Dyrskjøt Lars , Ørntoft Torben Falck
Published: April 2023

Lists of i) top30 exocytosed miRNAs and ii) cellular-retained miRNAs.
Supplementary Figure 3 from Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties
Authors: Ostenfeld Marie Stampe , Jeppesen Dennis K. , Laurberg Jens R. , Boysen Anders T. , Bramsen Jesper B. , Primdal-Bengtson Bjarke , Hendrix An , Lamy Philippe , Dagnaes-Hansen Frederik , Rasmussen Mads H. , Bui Khan H. , Fristrup Niels , Christensen Erik I. , Nordentoft Iver , Morth Jens P. , Jensen Jørgen B. , Pedersen Jakob S. , Beck Martin , Theodorescu Dan , Borre Michael , Howard Kenneth A. , Dyrskjøt Lars , Ørntoft Torben Falck
Published: April 2023

Analysis of RAB27A and RAB27B expression and genomic alterations in clinical samples. Effect of Rab27b knockdown on cell morphology and long-term growth kinetics.
Supplementary Figure S2 from Sentinel Lymph Node Biopsy Revisited: Ultrasound-Guided Photoacoustic Detection of Micrometastases Using Molecularly Targeted Plasmonic Nanosensors
Authors: Luke Geoffrey P. , Myers Jeffrey N. , Emelianov Stanislav Y. , Sokolov Konstantin V.
Published: April 2023

MAPS allow differentiation of delivery and molecular interactions.
Supplementary Figure Legends from Sentinel Lymph Node Biopsy Revisited: Ultrasound-Guided Photoacoustic Detection of Micrometastases Using Molecularly Targeted Plasmonic Nanosensors
Authors: Luke Geoffrey P. , Myers Jeffrey N. , Emelianov Stanislav Y. , Sokolov Konstantin V.
Published: April 2023

Legend for Supplementary Figures S1-S2.
Data Supplement from NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis
Authors: Weaver Kelly L. , Alves-Guerra Marie-Clotilde , Jin Ke , Wang Zhiqiang , Han Xiaoqing , Ranganathan Prathibha , Zhu Xiaoxia , DaSilva Thiago , Liu Wei , Ratti Francesca , Demarest Renee M. , Tzimas Cristos , Rice Meghan , Carpio Rodrigo Vasquez-Del , Dahmane Nadia , Robbins David J. , Capobianco Anthony J.
Published: April 2023

Supplemental Table 1. Oligo sequences.
Supplementary Materials and Methods, Figure Legends from Flotillin-1 Regulates Oncogenic Signaling in Neuroblastoma Cells by Regulating ALK Membrane Association
Authors: Tomiyama Arata , Uekita Takamasa , Kamata Reiko , Sasaki Kazuki , Takita Junko , Ohira Miki , Nakagawara Akira , Kitanaka Chifumi , Mori Kentaro , Yamaguchi Hideki , Sakai Ryuichi
Published: April 2023

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Supplementary Table S1 from Oncogenic Properties of a Spermatogenic Meiotic Variant of Fer Kinase Expressed in Somatic Cells
Authors: Yaffe Etai , Hikri Elad , Elkis Yoav , Cohen Ortal , Segal Ariela , Makovski Adar , Varvak Alexander , Shpungin Sally , Nir Uri
Published: April 2023

Supplementary Table S1: lists the different siRNA's used in the currently described work
Data Supplement from Immediate Utility of Two Approved Agents to Target Both the Metabolic Mevalonate Pathway and Its Restorative Feedback Loop
Authors: Pandyra Aleksandra , Mullen Peter J. , Kalkat Manpreet , Yu Rosemary , Pong Janice T. , Li Zhihua , Trudel Suzanne , Lang Karl S. , Minden Mark D. , Schimmer Aaron D. , Penn Linda Z.
Published: April 2023

Supplementary Figure 1. A drug screen reveals dipyridamole as potentiating the anti-proliferative effects of atorvastatin and fluvastatin. Supplementary Figure 2. Dipyridamole enhances the effects of statin-induced MVA pathway inhibition. Supplementary Figure 3. The relative sensitivity to doxorubicin in 8226DOX and 8226 parental cells is not significantly altered in response to dipyridamole exposure. Supplementary Figure 4. Dipyridamole prevents the statin induced upregulation of HMGCR and HMGCS1. Supplementary Figure 5. Dipyridamole prevents the statin induced upregulation of HMGCR and HMGCS1 through inhibition of SREBP2 cleavage in OCI-AML2 cells. Supplementary Figure 6: Working model of how dipyridamole potentiates the anticancer effects of statins. Supplementary Table 1. Composition of the chemical library.
Supplementary Figure S2 from Efficacy of CAR T-cell Therapy in Large Tumors Relies upon Stromal Targeting by IFNγ
Authors: Textor Ana , Listopad Joanna J. , Wührmann Lara Le , Perez Cynthia , Kruschinski Anna , Chmielewski Markus , Abken Hinrich , Blankenstein Thomas , Charo Jehad
Published: April 2023

9-28-ζ-CAR expression on mouse T cells compared to ζ-CARs
Supplementary Figure 2 from miR326 Maturation Is Crucial for VEGF-C–Driven Cortactin Expression and Esophageal Cancer Progression
Authors: Hong Chih-Chen , Chen Pai-Sheng , Chiou Jean , Chiu Ching-Feng , Yang Ching-Yao , Hsiao Michael , Chang Yi-Wen , Yu Yang-Hao , Hung Mien-Chie , Hsu Nai-Wen , Shiah Shine-Gwo , Hsu Nan-Yung , Su Jen-Liang
Published: April 2023

Supplementary Figure 2. The phosphorylated VEGFR-3 in TE-1 cells with VEGF-C and VEGF-A treatment. TE-1 cells were starved with serum-free medium for 16 hours and treated with 100 and 200 ng/mL VEGF-C as well as 200 ng/mL VEGF-A for 10 minutes, following examination of phosphorylated VEGFR-3 (p-VEGFR-3, Y1063/1068) expression by Western blot. β-actin was used as an internal control.
Data Supplement from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets
Authors: Taguchi Ayumu , Taylor Allen D. , Rodriguez Jaime , Çeliktaş Müge , Liu Hui , Ma Xiaotu , Zhang Qing , Wong Chee-Hong , Chin Alice , Girard Luc , Behrens Carmen , Lam Wan L. , Lam Stephen , Minna John D. , Wistuba Ignacio I. , Gazdar Adi F. , Hanash Samir M.
Published: April 2023

Supplementary Table S4. Gene expression profiles (log2 intensity) of 11 selected CT antigens and VCX in 83 pairs of lung adenocarcinoma tissues and normal adjacent tissues.
Data Supplement from Cryotherapy with Concurrent CpG Oligonucleotide Treatment Controls Local Tumor Recurrence and Modulates HER2/neu Immunity
Authors: Veenstra Jesse J. , Gibson Heather M. , Littrup Peter J. , Reyes Joyce D. , Cher Michael L. , Takashima Akira , Wei Wei-Zen
Published: April 2023

Supplementary Figure S2. BALB/c mice were inoculated with TUBO 3d before adoptive serum transfer of 25 µg equivalent α-neu Ab from mice previously treated with cryo + CpG or pNeuE2 vaccination, naïve control serum, or 25 µg monoclonal Ab4 (n=3-5) as a single tail vein injection in a total volume of 200 µL with PBS. TUBO tumor volume 30 days after inoculation. **P<0.01
Supplementary Video #3 from Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform
Authors: Wong Andrew D. , Searson Peter C.
Published: April 2023

Multiple MDA-MB-231 breast cancer cells moving within a predefined matrix tunnel next to an HMVEC vessel under shear stress (12-15 dyne cm-2).
Supplemental Tables S1-S2 from Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers
Authors: Gan Gregory N. , Eagles Justin , Keysar Stephen B. , Wang Guoliang , Glogowska Magdalena J. , Altunbas Cem , Anderson Ryan T. , Le Phuong N. , Morton J. Jason , Frederick Barbara , Raben David , Wang Xiao-Jing , Jimeno Antonio
Published: April 2023

Supplemental Tables S1-S2. Hirsch Score was calculated from tumors and their respective stroma from Figure 5 (S1); All potential flank implanted stromal:tumor and tumor:tumor combinations were measured bi-weekly to chart growth kinetics (S2).
Supplemental Table S1 from Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
Authors: Tran Hung D. , Luitel Krishna , Kim Michael , Zhang Kun , Longmore Gregory D. , Tran David D.
Published: April 2023

Supplemental Table S1. Spatiotemporal expression of SNAIL1 in MMTV-PyMT mice
Supplemental Figure S6 from Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
Authors: Tran Hung D. , Luitel Krishna , Kim Michael , Zhang Kun , Longmore Gregory D. , Tran David D.
Published: April 2023

Supplemental Figure S6. Related to Figure 5D: SNAIL1 is not expressed by lung metastases in mice overexpressing SNAIL1 in primary breast tumors
Supplemental Figure S5 from Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
Authors: Tran Hung D. , Luitel Krishna , Kim Michael , Zhang Kun , Longmore Gregory D. , Tran David D.
Published: April 2023

Supplemental Figure S5. Related to Figure 4C-E: Primary breast tumors in Early SNAIL1 KO exhibit loss of EMT phenotype and metastatic potential