bluuebunny/crossref_metadata_2025 huggingface dataset:
WATER HYACINTH: CLEARING THEM FROM KELAPA DUA LAKE AND UTILIZING THEM FOR HANDICRAFTS
Authors: Karnelasatri Karnelasatri - , Kurnia Rieswan Pangawira , Hardy Junius
Published: March 2021

Kelapa Dua Lake is important for the local community as a water catchment and reservoir. At certain times of the year, water hyacinth grown and spread rapidly due to the lake's high nutrient content, including nitrogen, phosphate, and potassium. These are indicators of pollution from the surrounding populated areas. Inappropriate and poorly timed countermeasures against this invasive species have had many negative effects. One countermeasure that could work, however, is harvesting the water hyacinth as a raw material for handicrafts. A joint team of lecturers, UPH service learning, students, a team from the National Disaster Management Agency (BNPB), the Indonesian local government, and local resident carried out a collaborative event to clear one section of Kelapa Lake of both water hyacinth and plastic waste. A numbers of water hyacinth were collected and then processed as a basic material for handicraft products. These handicraft products were then exhibited at an environmental education concert attended by invited guests, including representatives of the Kelapa Dua local government. This event is expected to provide new information about the processing and use of water hyacinth, highlighting its economic value and encouraging more positive activities to decrease water hyacinth and protect the environment.

ABSTRACT (INDONESIAN): Danau Kelapa Dua merupakan danau yang sangat penting bagi masyarakat setempat sebagai tempat resapan dan tampungan air. Pertumbuhan eceng gondok di danau ini cukup cepat pada masa waktu tertentu karena adanya kemungkinan air danau yang memiliki kandungan nutrien tinggi seperti nitrogen, fosfat, dan potasium. Oleh sebab itu, invasi eceng gondok pada danau ini menjadi salah satu indikator pencemaran air dari berbagai aktivitas warga di sekitarnya. Penanggulangan yang terlambat dan kurang tepat terhadap invasi eceng gondok memberikan banyak dampak negatif. Salah satu pengontrolan invasi eceng gondok dapat dilakukan dengan memanfaatkannya sebagai bahan baku kerajinan tangan. Kegiatan gotong royong membersihkan eceng gondok dan sampah plastik pada salah satu area danau Kelapa Dua telah dilakukan oleh gabungan tim dosen, service learning UPH, mahasiswa dari berbagai jurusan, tim dari Badan Nasional Penanggulangan Bencana (BNPB), pemerintah dan warga setempat. Setelah kegiatan gotong royong, sejumlah eceng gondok yang dikumpulkan kemudian diolah sebagai bahan dasar produk kerajinan tangan. Berbagai produk kerajinan tangan kemudian dipamerkan pada konser musik edukasi lingkungan. Presentasi produk disaksikan oleh tamu-tamu undangan konser termasuk perwakilan pemerintah daerah Kelapa Dua. Kegiatan ini diharapkan dapat memberikan informasi baru tentang pengolahan eceng gondok agar bernilai ekonomis serta melakukan kegiatan positif untuk menjaga lingkungan.
Impact of Influencers in Consumer Decision Process: The Fashion Industry
Authors: Nurfadila Siti
Published: March 2021

The popularity of influencers is continuous and doesn’t have a limited window of influence. Internet and social media play vital role in helping consumers find the items they are looking for. Obviously companies will keenly try to retain a strong presence in the social media platforms; otherwise the target audience can easily change suppliers. The present   study is intended to explore the influencer marketing techniques used by fashion industries and also the impact of influencers on the consumers buying decision process in fashion industry.
Exequatur, nulidad de actuaciones e indefensión… y otras cuestiones no menos relevantes (auto de la Audiencia Provincial de Barcelona de 18 de mayo de 2020)
Authors: Iglesias Maria del Ángel
Published: March 2021

El presente comentario versa sobre el Auto de la Audiencia Provincial de Barcelonade 18 de mayo de 2020 que, a priori, no parecería tener mayor interés si tomamos como referencia los descriptores de la decisión. Sin embargo, merece la pena detenerse en el análisis de determinadas referencias que el Auto contiene, como las efectuadas respecto de la jurisdicción voluntaria, del pacto al que puede llegarse en el marco de un procedimiento contencioso y respecto de éste mismo. Ello, junto a lo que constituye el núcleo de la decisión: la validez en España de una decisión tomada en Ecuador relativa a alimentos de menores y la alegada nulidad de actuaciones, junto a la vulneración de uno de los derechos esenciales del debido proceso, al no haberse dado traslado debido de la demanda a la contraparte.
Imposibilidad de privar de potestad parental a los padres biológicos en virtud de una kafala en España (SAP Barcelona 11 junio 2020)
Authors: Orbegozo Miguel Xabier
Published: March 2021

La sentencia objeto del presente comentario aborda la posibilidad de desposeer de la potestad parental a los progenitores de una menor argelina en virtud de una kafala otorgada en dicho país en favor de su tía, con la que reside de manera regular en España. La kafil, tía de la menor, recurre a la citada institución de Derecho islámico para solicitar, previa privación de las potestades parentales a los progenitores, la tutela de la menor, solicitud que rechaza el tribunal español por no concurrir los requisitos que establece la legislación civil catalana para la constitución de esta figura.
El régimen jurídico de las redes sociales y los retos que plantea el acceso a dichas plataformas
Authors: Sánchez Cano María Jesús , Romero Matute Yeray
Published: March 2021

Recientemente, hemos visto como un partido político español con representación parla-mentaria anunció que había interpuesto acciones legales ante los tribunales españoles contra Twitter, por una presumible vulneración de “derechos fundamentales como la libertad de expresión, el derecho a la participación política, la libertad ideológica y el principio de pluralismo e igualdad política, recogidos to-dos en la Constitución”. Esta noticia pone en evidencia varias cuestiones que no suelen tenerse en cuenta por el usuario medio a la hora de acceder a cualquiera de las redes sociales más utilizadas, como pueden ser, Twitter, Facebook, Instagram o LinkedIn. Ante esta tesitura, se analizará desde una perspectiva inter-nacional privatista la naturaleza del contrato, así como las cláusulas de sumisión incluidas en los mismos.
Esther Arroyo Amayuelas, Sergio Cámara Lapuente (Dir.). El Derecho privado en el nuevo paradigma digital
Authors: Santos Morón María José
Published: March 2021

Este artículo reseña: Esther Arroyo Amayuelas, Sergio Cámara Lapuente (Dir.). El Derecho privado en el nuevo paradigma digital. Colegio Notarial de Cataluña, Marcial Pons, 2020, 536 págs. ISBN 978-84-9123-845-4
Introduction A Milestone in the Life of a Journal
Authors: Mårtensson Katarina , Schrum Kelly
Published: March 2021

An introduction to volume 9, issue 1 of Teaching & Learning Inquiry.
Foreword: 2019 International Collaborative Writing Groups (ICWGs)
Authors: Scharff Lauren , Divan Aysha , Motley Phillip
Published: March 2021

Collaborative research and writing across disciplines and institutions happens frequently in discipline-based research. However, opportunities for cross-collaborative scholarship in teaching and learning is limited in comparison (Kahn et al., 2013; MacKenzie and Myers, 2012). Yet the value of larger scale, team-based approaches to scholarly writing is well recognised in building networks and in providing a deeper understanding of a topic as informed by multi-disciplinary and/or international perspectives (Marquis et al., 2014; 2015; Matthews et al., 2017). It is for these reasons that the International Collaborative Writing Groups (ICWG) program that crystallises around the International Society for the Scholarship of Teaching and Learning (ISSOTL) conference is so valuable. ICWGs bring together academics, professional staff, and students to co-author learning and teaching articles on topics of shared interest. The aims are two-fold: 1) to build capacity of participants to work and write with international collaborators, and 2) to contribute meaningful and topical perspectives to the SoTL literature.
Exploring the Emotional Responses of Undergraduate Students to Assessment Feedback: Implications for Instructors
Authors: Hill Jennifer , Berlin Kathy , Choate Julia , Cravens-Brown Lisa , McKendrick-Calder Lisa , Smith Susan
Published: March 2021

Summative assessments tend to be viewed as high-stakes episodes by students, directly exposing their capabilities as learners. As such, receiving feedback is likely to evoke a variety of emotions that may interact with cognitive engagement and hence the ability to learn. Our research investigated the emotions experienced by undergraduate students in relation to assessment feedback, exploring if these emotions informed their learning attitudes and behaviours. Respondents were drawn from different years of study and subject/major. A qualitative approach was adopted, using small group, semi-structured interviews and reflective diaries. Data were analysed thematically and they revealed that receiving feedback was inherently emotional for students, permeating their wider learning experience positively and negatively. Many students struggled to receive and act upon negative feedback, especially in early years, when it was often taken personally and linked to a sense of failure. Negative emotional responses tended to reduce students’ motivation, self-confidence, and self-esteem. Some students, especially in later years of study, demonstrated resilience and engagement in response to negative feedback. By contrast, positive feedback evoked intense but fleeting emotions. Positive feedback made students feel cared about, validating their self-worth and increasing their confidence, but it was not always motivational. The paper concludes with recommendations for instructors, highlighting a need to communicate feedback carefully and to develop student and staff feedback literacies.
Brokering Boundary Crossings through the SoTL Landscape of Practice
Authors: Kensington-Miller Barbara , Webb Andrea , Gansemer-Topf Ann , Lewis Heather , Luu Julie , Maheux-Pelletier Geneviève , Hofmann Analise
Published: March 2021

This study examines the lived experiences of seven internationally diverse scholars from Canada, the United States, New Zealand, and Australia to answer the question: how do we make meaning of our collective boundary crossing experiences across disciplines and positions within SoTL? Our positions range from graduate student, faculty, and academic developers, to department chair and centre director. We conducted a phenomenological study, based on narratives of experience, and drew on Wenger-Trayner and Wenger-Trayner’s (2015) theoretical framework that explores the features of a landscape of practice. Guided by this framework, we analyze our boundary crossings and brokering across the “diverse, political and flat” features of the SoTL landscape. Our collective findings highlight the critical role brokers play in facilitating boundary crossings. Brokering is precarious, bringing people together, building trusting relationships, and developing legitimacy while negotiating deadlocks, bureaucracy, authorities, and a multitude of challenges. Brokers, we found, require strength and resilience to mobilise, influence, and drive change in the landscape to transform existing practices or create new ones. We suggest that our analytical process can be used as a tool of analysis for future research about how brokers influence the SoTL landscape of practice and how brokering enhances SoTL development, support, and leadership.
Prinsip Penegakan Hukum dan Hak Asasi Manusia: Studi Kasus Penembakan Militer Terhadap Masyarakat Nduga Papua
Authors: Simamora Andrean Gregorius Pandapotan , Budihardja Georgius Ivan
Published: March 2021

Pelanggaran HAM di Papua seringkali terjadi (10 tahun terakhir) banyaknya faktor-faktor yang menghambat dalam penuntasan kasus pelanggaran HAM yang terjadi di Papua, terkhusus di Nduga adanya 2 (dua) warga sipil papua dibunuh oleh kalangan militer karena diduga kalangan Organisasi Papua Merdeka, walaupun pemerintah telah mengetahui tindakan brutal tersebut, tidak adanya penindakan tegas untuk menuntas kasus tersebut secara jelas. Dalam Instruksi Presiden Jokowi telah ada agenda untuk menuntaskan pelanggaran HAM dan memperbaiki kesejahteraan rakyat Papua, tetapi Presiden Jokowi hanya memprioritaskan infrastruktur atau pembangunan di Papua, padahal presiden telah mengetahui adanya pelanggaran HAM. Sebelum Jokowi dilantik sebagai Presiden pada saat Pilpres 2019 lalu, Jokowi berjanji akan menuntaskan baik menyelesaikan pelanggaran HAM yang terjadi di Indonesia, khususnya daerah Papua yang selama ini memiliki historis pelanggaran HAM yang sangat banyak, sehingga hal ini sangat bertentangan dengan ideologi Indonesia yang menjungjung tinggi Hak Asasi Manusia.
Correlation Between Knowledge And Attitude Toward Personal Menstrual Hygiene Practice Among Adolescents
Authors: Andani Pinesa Rachma
Published: March 2021

Saat ini telah terjadi pergeseran usia seorang remaja putri mengalami mentruasi untuk pertaman kali atau menarche dini. Semakin muda usia menarche sebaiknya diimbangi dengan kesiapan remaja baik secara psikologis maupun pengetahuan tentang menstruasi dan personal hygiene menstruasi yang memadai. Saat menstruasi organ seksual menjadi lebih sensitif sehingga rentan terkena infeksi. Sehingga sangat penting melakukan tindakan personal hygiene menstruasi dengan baik dan benar. Tingkat pengetahuan dan sikap cenderung mempengaruhi tindakan seseorang. Tujuan dari penelitian ini adalah untuk mengetahui hubungan tingkat pengetahuan dan sikap terhadap tindakan personal hygiene menstruasi pada siswi SDN Kertajaya Kota Surabaya. Penelitian ini merupakan penelitian kuantitatif dengan desain cross-sectional. Responden dalam penelitian ini diambil dengan metode total sampling dan diperoleh jumlah responden sebanyak 78 orang. Pengumpulan data dilakukan dengan menggunakan kuesioner, observasi dan wawancara. Diperoleh hasil 66,7% responden memiliki pengetahuan yang baik, 60,3% persen responden memiliki sikap baik dan 79,5% responden memiliki tindakan baik. Kesimpulan dari penelitian ini, ada hubungan antara tingkat pengetahuan dan sikap terhadap tindakan personal hygiene menstruasi pada siswi SDN Kertajaya Kota Surabaya.
Human Resource Information System and Work Stress during COVID-19 Pandemic
Authors: Munir Misnal , Amaliyah Amaliyah , Pandin Moses Glorino Rumambo
Published: March 2021

The increasingly rapid flow of technological development is now a tool to improve backwardness, renew the system, as well as a means of improvement in various aspects of life. For companies, the development of information and communication technology is a new innovation or breakthrough to improve service quality. Various benefits provided by technology and information. However, if not handled properly, technology and information will become a boomerang for an organization. HRIS is the application of HRM functions in the application of information and communication technology. The concept of HRIS as a digital form of HRM is increasing along with the outbreak of the Covid-19 pandemic which has caused a large loss impact on all lines of life. The limitation of social interaction in an effort to prevent the wider spread of covid-19 and the higher number of casualties causes business activities to stall. This research uses quantitative methods with a study sample of 100 randomly selected. This study aims to see how clarity of high-tech goals in human resources management, perceived benefits, perceived ease of use, company conditions that can influence attitudes towards HRIS.
Enhancement of Performance and Competency-Based on Optimization of Intellectual Capital Model: The Critical Thinking Analysis
Authors: Trisliatanto Dimas , Iswati Sri , Suaedi Falih , Sutanto Eddy , Wijoyo Suparto , Hadi Cholichul , Adam Subagyo , Pandin Moses Glorino Rumambo
Published: March 2021

The era of globalization of the industrial revolution 4.0 was also marked by rapid economic, social, scientific, and technological developments. Currently, the company was demanded to maximize all its potential to compete with other companies. For this reason, it was hoped that companies could understand the importance of knowledge management-based intellectual capital through outreach, externalization, internalization, and combinations that had implications for improving employee performance and competency. This study was to identify and describe the enhancement of performance and competency-based on the optimization of the intellectual capital model in terms of critical thinking analysis. This study used a qualitative approach with critical thinking analysis through literature study methods. The findings results of this study were to improve performance and competency were the basic measurement models of intellectual capital, new intellectual capital measurement models in empirical studies, intellectual capital measurement models with bottlenecks, and environmental-based intellectual capital models. This study concluded that intellectual capital measurement should be determined as accumulation and interpretation in the proposed model for a company that was an applied subject with a qualitative intellectual capital index system, to provide a good tool for companies to managed intellectual capital.
De Novo Spatial Reconstruction of Single Cells by Developmental Coalescent Embedding of Transcriptomic Networks
Authors: Zhao Yuxuan , Zhang Shiqiang , Cannistraci Carlo Vittorio , Han Jing-Dong J.
Published: March 2021

Single cell RNA-seq (scRNA-seq) profiles conceal temporal and spatial tissue developmental information. De novo reconstruction of single cell temporal trajectory has been fairly addressed, but reverse engineering single cell 3D spatial tissue localization is hitherto landmark based, and de novo spatial reconstruction is a compelling computational open problem. Here we show that a new algorithm - named D-CE - for coalescent embedding of single cell transcriptomic networks can address this open problem. We rely merely on the spatial information encoded in the expression patterns of developmental signal transcription factor (DST) genes, and we find that D-CE of cell-cell association DST-transcriptomic networks reliably reconstructs the Geo-seq or single cell samples’ 3D spatial tissue distribution. Comparison to the novoSpaRC and CSOmap (recent and only available de novo 3D spatial reconstruction methods) on 16 datasets and 681 reconstructions, reveals a significantly distinctive superior performance of D-CE.
Strategies for Improving the Sustainability of Data Centers via Practical and Effective Measures Such as Changing Energy Mix, Enhancing Energy Efficiency, Reducing Energy Use, and Circular Energy or Recycling Energy
Authors: Manganelli Matteo , Soldati Alessandro , Martirano Luigi , Ramakrishna Seeram
Published: March 2021

Information and communication technologies (ICT) are increasingly permeating our daily life and we ever more commit our data to the cloud. Events like the COVID-19 pandemic put an exceptional burden upon ICT infrastructures. This involves implementation and utilization of data centers, which increasingly contribute to energy and environmental impact. In this work, we address strategies to improve energy efficiency of data centers, to enhance sustainability towards energy resource and the environment. Among key strategies are innovative cooling technologies, use of natural resources, automation techniques, low-power electronics, and equipment with extended thermal limits. Research perspectives are identified and estimates of improvement opportunities are presented.
Gas Exchange, Water Use Efficiency, and Biomass Partitioning Among Geographic Sources of Acer saccharum subsp. saccharum and subsp. nigrum seedlings in Response to Water Stress
Authors: Hauer Richard J. , Wei Hongxu , Koeser Andrew K. , Dawson Jeffrey O.
Published: March 2021

Responses to water stress were measured for sugar maple (Acer saccharum subsp. saccharum Marshall) sources from Oklahoma (Caddo sugar maple), Missouri, Tennessee, Ontario and a black maple (Acer saccharum subsp. nigrum F. Michx.) source from Iowa. Seedling sources were selected for differences in temperature and precipitation of their geographic origins. Seedlings were preconditioned through moist (watered daily) or dry (watered every 4-7 days) cycles and then exposed to prolonged water stress. Dry preconditioned sugar maple seedlings from Oklahoma, Missouri, and Tennessee, sources from warmer and/or drier climates with greater relative evapotranspiration potentials, declined less rapidly in net photosynthesis, stomatal conductance, and water use efficiency (WUE) as water stress increased than dry preconditioned seedlings from Ontario and Iowa having origins in cooler, moister climates. Under imposed water stress the Ontario and Iowa sourced seedlings increased their root to shoot ratios and decreased their specific leaf area, mechanisms for drought avoidance. However, no corresponding changes in these values occurred for Oklahoma, Missouri, and Tennessee sources. Results from this study suggest greater tolerance of water stress in the Oklahoma, Missouri and Tennessee ecotypes from the western and southern range of sugar maple resulted primarily with WUE rather than other water stress coping mechanisms.
Prosthetic Meshes for Hernia Repair: State of Art, Classification, Antimicrobial Approaches, and Fabrication Methods
Authors: Serrano-Aroca Ángel , Pous-Serrano Salvador
Published: March 2021

Worldwide, hernia repair represents one of the most frequent surgical procedures encompassing a global market valued at several billion dollars. This type of surgery usually requires the implantation of a mesh that needs the appropriate chemical, physical and biological properties for the type of repair. This review thus presents a description of the types of hernias, current hernia repair methods, and the state of the art of prosthetic meshes for hernia repair providing the most important meshes used in clinical practice by surgeons working in this area classified according to their biological or chemical nature, morphology and whether bioabsorbable or not. We emphasise the importance of surgical site infection in herniatology, how to deal with this microbial problem, and we go further into the future research lines on the production of advanced antimicrobial meshes to improve hernia repair and prevent microbial infections, including multidrug-resistant strains. A great deal of progress has been made in this biomedical field in the last decade. However, we are still far from an ideal antimicrobial mesh that can also provide excellent integration to the abdominal wall, mechanical performance, low visceral adhesion and minimal inflammatory or foreign body reactions, among many other problems.
Kajian Dehidroksilasi Termal Kaolin menjadi Metakaolin menggunakan Analisis Termogravimetri
Authors: Purbasari Aprilina , Samadhi Tjokorde Walmiki
Published: March 2021

Kaolin merupakan mineral yang banyak dimanfaatkan di berbagai industri. Kaolin dapat diubah menjadi metakaolin yang lebih reaktif melalui proses dehidroksilasi termal. Pada penelitian ini, proses dehidroksilasi termal kaolin dari Bangka Belitung menjadi metakaolin dikaji menggunakan analisis termogravimetri pada rentang suhu 30 – 900 °C dengan laju pemanasan 10 °C/menit dalam lingkungan atmosfer udara. Kaolin mengalami empat tahap dekomposisi dan dehidroksilasi kaolin menjadi metakaolin terjadi pada suhu sekitar 450 – 600 °C. Berdasarkan metode Coats dan Redfern, dehidroksilasi kaolin mengikuti model reaksi order satu dengan energi aktivasi 271,66 kJ/mol dan faktor pre-eksponensial 6,13×1015 s-1. Hasil analisis menggunakan spektroskopi X-ray diffraction (XRD) dan Fourier Transform Infrared (FTIR) pada kaolin setelah dipanaskan pada suhu 550 °C selama 3 jam menunjukkan bahwa sebagian besar kaolin telah berubah menjadi metakaolin.

Study of Thermal Dehydroxylation of Kaolin to Metakaolin using Thermogravimetric Analysis. Kaolin is a mineral that is widely used in various industries. Kaolin can be converted into metakaolin which is more reactive through thermal dehydroxylation processes. In this study, thermal dehydroxylation process of Bangka Belitung kaolin into metakaolin was studied using thermogravimetric analysis in a temperature range of 30 – 900 °C with a heating rate of 10 oC/min in an air atmosphere condition. Kaolin underwent four stages of decomposition and dehydroxylation of kaolin into metakaolin occured at temperatures around 450 – 600 °C. Based on the Coats and Redfern method, kaolin dehydroxylation followed first order reaction model with activation energy of 271.66 kJ/mol and pre-exponential factor of 6.13×1015 s-1. The analysis using X-ray diffraction (XRD) dan Fourier Transform Infrared (FTIR) spectroscopy on kaolin after heating at temperature of 550 °C for 3 hours showed that most of the kaolin had turned into metakaolin.
Pengaruh Model Pembelajaran Missouri Mathematics Project dan Self-Efficacy terhadap Kemampuan Berpikir Kritis Siswa
Authors: Khoirunnisa  , Ellis Salsabila  , Vera Maya Santi
Published: March 2021

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran missouri mathematics project dan self-efficacy terhadap kemampuan berpikir kritis siswa. Metode penelitian yang digunakan adalah kuasi eksperimen dengan populasi seluruh siswa SMP Negeri 232 Jakarta pada tahun ajaran 2019-2020 dengan sampel yang terdiri dari 64 siswa. Penelitian ini dilaksanakan pada bulan Februari sampai Maret 2020 pada pokok bahasan aritmatika sosial. Data yang digunakan diperoleh dari hasil tes kemampuan berpikir kritis dan hasil angket self-efficacy. Rancangan penelitian yang digunakan dalam penelitian ini adalah treatment by level 2x2. Teknik analisis data menggunakan uji ANOVA dua jalan untuk mengetahui pengaruh utama dan pengaruh interaksi serta menggunakan uji Tukey untuk mengetahui pengaruh sederhana dengan taraf nyata 5%. Hasil penelitian menunjukan bahwa: (1) kemampuan berpikir kritis siswa kelompok yang diajar menggunakan model pembelajaran missouri mathematics project lebih tinggi dibanding kelompok yang diajar menggunakan model pembelajaran konvensional, (2) terdapat pengaruh interaksi antara penggunaan model pembelajaran missouri mathematics project dan self-efficacy terhadap kemampuan berpikir kritis siswa, (3) pada siswa dengan self-efficacy tinggi, kemampuan berpikir kritis siswa yang diajar menggunakan model pembelajaran missouri mathematics project lebih tinggi dari siswa yang diajar menggunakan model pembelajaran konvensional, (4) pada siswa dengan self-efficacy rendah, tidak terdapat perbedaan yang signifikan antara kemampuan berpikir kritis siswa yang diajar menggunakan model pembelajaran missouri mathematics project dengan siswa yang diajar menggunakan model pembelajaran konvensional.
Efektivitas Blended Learning Berbasis LMS dalam Pembelajaran Matematika
Authors: Leny Dhianti
Published: March 2021

Perkembangan teknologi mempunyai pengaruh besar dalam bidang pendidikan. Hal itu dapat dilihat dari berbagai inovasi-inovasi dalam bidang pendidikan yang menerapkan teknologi dalam pelaksanaannya, salah satunya dalam proses pembelajaran. Salah satu contoh penerapan ICT dalam pembelajaran yaitu penggunaan e-learning pada proses pembelajaran. Salah satu penerapan e-learning dalam pembelajaran yaitu penggunaan Learning Management System (LMS), di antaranya Schoology, Edmodo, dan Google Classroom. Salah satu model pembelajaran yang menerapkan ICT adalah model blended learning. Penelitian ini merupakan penelitian studi pustaka. Temuan utama dalam penelitian ini adalah penerapan model blended learning menunjukkan efektifitas yang baik dalam pembelajaran matematika. Hal itu dikarenakan penggunaan LMS mempermudah siswa dan guru dalam proses pembelajaran karena dapat diakses kapan saja dan dimana saja tanpa terbatas ruang dan waktu.
Universal Health Coverage “Leave No Child Behind “
Authors: Siderius Liesbeth , Neubauer David , Bhattacharya Anjan , Altorjai Péter , Margvelashvili Lali , Lamabadusuriya Sanath , Wierzba Jolanta , Mazur Artur , Albrecht Piotr , Tasic Velibor
Published: March 2021

Aim: Multiple stakeholders are involved in achieving Universal Health Coverage (UHC) as part of the Sustainable Development Goals (SDG). The estimated over 90 million children with disabilities are among the most vulnerable members of the world’s population. Paediatricians around the world are united to promote a world where all children, regardless of their abilities or disabilities, can enjoy a healthy life and well-being. We examined: ‘What would be the least paediatricians could do to contribute to the UHC?’Methods: In cross-sectional study paediatricians, engaged in care for children with disabling and rare conditions, were questioned on eight of the UHC statements concerning child health, primary care services, availability and affordability of diagnostics and therapies and digital health; as well as country of residence and level of practice.Results: Responders from Europe and Israel, Asia and the US practice at primary-, secondary- and tertiary care level in high and middle economy countries. Promotion of paediatric primary care could reduce mortality and morbidity, according to 39/48 (81%) respondents. An active role of paediatricians in providing quality information would increase access to health services for children with disabilities, according to 40/48 (83%) responders. Improved data exchange is necessary to deliver primary care as a cornerstone, according to 38/48 (79%) responders. Respondents practising in middle economy countries reported significantly more frequently than their colleagues in high economies countries about “out of pocket” payments for diagnostics and therapies as well as reduced availability. In order to increase global awareness and international solidarity, a panel of participants in a paediatric network felt that paediatricians should undertake necessary actions to support the achievement of UHC.Conclusion: The economic gap in diagnostic and therapeutic facilities in paediatric practice should be considered in achieving UHC. An international paediatric network should support achieving the UHC by providing adequate paediatric training and quality (digital) information.
Robust prognostic signatures derived from proteomic panel profiling of plasma from patients with severe COVID-19 complications
Authors: Al-Nesf Maryam , Abdesselem Houari , Bensmail Ilham , Ibrahim Shahd , Saeed Walaa , Mohammed Sara , Razok Almurtada , Alhussain Hashim , Aly Reham , Maslamani Muna Al , Ouararhni Khalid , Khatib Mohamad , Hssain Ali Ait , Omrani Ali , Al-Kaabi Saad , Khal Abdullatif Al , Althani Asma , Samsam Waseem , Farooq Abdulaziz , Al-Suwaidi Jassim , Al-Maadheedh Mohammed , Al-Siddiqi Heba , Butler Alexandra , Decock Julie , Mohamed-Ali Vidya , Al-Ejeh Fares
Published: March 2021

COVID-19 complications present a huge burden on healthcare systems and warrant a predictive risk model for disease severity of SARS-CoV-2 infection to enable early intervention, prospective decision-making and triaging of patients. We profiled plasma proteins from COVID-19 patients (severe n=50, and mild n=50) and controls (n=50) using function- and pathway-based panels developed with the highly specific proximity extension assays. Several biological pathways were specific for patients with severe complications. Based on these dysregulated profiles, we propose candidate FDA-approved drugs that target multiple upregulated proteins to treat severe complications. In addition, the set of differentially expressed plasma proteins in severe disease contained a robust 46-protein signature, the COVID-19 molecular severity score, which predicts the risk of severe complications. We cross-validated this molecular severity score in an independent cohort and found it useful within three days after hospital admission to predict COVID-19 severity and outcomes. Associated with the molecular severity score, we identified a set of clinical parameters available at admission, that act as a clinical risk score for complications. The molecular and clinical risk scores described in our study may be prognostic tools for severe COVID-19 disease and help alleviate the pressure on healthcare systems during infection peaks.
Revealing the Transmission Dynamics of COVID-19: A Bayesian Framework for Rt Estimation
Authors: Yang Xian , Wang Shuo , Xing Yuting , Li Ling , Xu Richard Yi Da , Friston Karl , Guo Yike
Published: March 2021

In epidemiological modelling, the instantaneous reproduction number, Rt, is important to understand the transmission dynamics of infectious diseases. Current Rt estimates often suffer from problems such as lagging, averaging and uncertainties demoting the usefulness of Rt. To address these problems, we propose a new method in the framework of sequential Bayesian inference where a Data Assimilation approach is taken for Rt estimation, resulting in the state-of-the-art ‘DARt’ system for Rt estimation. With DARt, the problem of time misalignment caused by lagging observations is tackled by incorporating observation delays into the joint inference of infections and Rt; the drawback of averaging is improved by instantaneous updating upon new observations and a model selection mechanism capturing abrupt changes caused by interventions; the uncertainty is quantified and reduced by employing Bayesian smoothing. We validate the performance of DARt through simulations and demonstrate its power in revealing the transmission dynamics of COVID-19.
Efficacy of a Tailored Moisturizer for Reducing Chemotherapy-Induced Skin Dryness in Breast Cancer Patients: A Randomized Controlled Trial
Authors: Kang Danbee , Kim Nayeon , Im Young Hyuck , Park Yeon Hee , Kim Ji Yeon , Park Hyeokgon , Kim Eunjoo , Zhao Di , Guallar Eliseo , Ahn Jin Seok , Cho Juhee
Published: March 2021

Introduction: While up to 60% of breast cancer patients undergoing chemotherapy experience skin side effects reducing quality of life, it was unclear which individual product was beneficial. To evaluate the effectiveness of a tailored moisturizer with a high content (1.5%) of pseudo-ceramides on skin dryness due to chemotherapy in breast cancer patients. Methods: Randomized controlled trial conducted from February 2015 to October 2018. 204 breast cancer patients experiencing skin dryness after 1 cycle of chemotherapy were randomly assigned to 3 groups (tailored moisturizer with high pseudo-ceramide content; general moisturizer; and usual care). Skin dryness, dullness, quality of life, and changes in sebum level were assessed at baseline, 3 weeks, and 1 month after completion of chemotherapy. The primary objective of the trial was to compare the tailored moisturizer group to usual care.Results: At 1 month after completion of chemotherapy, the tailored moisturizer group was significantly less likely to report severe skin dryness compared to the usual care group (8.5 vs. 27.9%, respectively, P < 0.01). The tailored moisturizer group reported significantly lower levels of skin dullness and lower levels of impairment of dermatological quality of life compared with the other two groups. Conclusions: A tailored moisturizer with a high content of pseudo-ceramides improved skin dryness, dullness and dermatological quality of life compared to usual care in breast cancer patients undergoing chemotherapy.
Pair production tomography imaging
Authors: Lyu Qihui , Neph Ryan , Sheng Ke
Published: March 2021

X-ray Computed Tomography (CT) is an exceptionally versatile tool for diagnosis and detection. Despite numerous technological evolutions, the underlying mechanism for CT image formation has not changed. To markedly expand beyond the current capacity of X-ray CT based on a new image formation mechanism, we introduce pair production tomography (P2T) imaging. Unlike CT, whose signals arise from attenuation of the incident photons, P2T collects coincident annihilation photons originated from the pair production interaction with high energy X-rays for tomographic reconstruction. We studied three P2T acquisition methods, including filtered back projection (FBP), time-of-flight (TOF), and scanning pencil beam (SPB). Using Monte Carlo simulation on phantom and patient data, we demonstrate three distinctly new capabilities for P2T: high linearity with the material atomic number for element mapping and soft tissue differentiation, the ability to form tomography with as few as a single heavily truncated X-ray beam, and in vivo radiotherapy treatment dose verification and monitoring. Among the three P2T acquisition methods, FBP is the least technically demanding, but its utility is limited to high radiation dose procedures such as radiotherapy treatment monitoring. Both TOF and SPB result in high signal-to-noise ratio (SNR) P2T images with a typical imaging dose. The quality of TOF relies on the time resolution of detectors. In comparison, SPB suppresses localization errors based on the known excitation path, which significantly mitigates the detector time resolution requirement.
Numerical Analysis of Welded Branch Tube Operating in Creep Range
Authors: Jelwan Jad Antonios , Bassil Charbel
Published: March 2021

Pressure components used in energy and resources industries may be subjected to various damages including plasticity and creep. Life prediction of such components is an important consideration for engineers who design, build, or operate them. This paper aims to present a comprehensive study to investigate the problem of creep life assessment of a complex welded component containing multiple zones with different material properties unlike almost all of the previously developed methods that have been based on the secondary creep condition alone that cannot be considered as a true representative for the creep behaviour of materials. Thus, the necessary information to estimate the life of a branch tube based on the primary, secondary, and tertiary creep conditions are presented. Results confirm the experimental data from the literature producing the most conservative life.
Canada’s Response to International Travel During COVID-19 Pandemic – A Media Analysis 
Authors: Re K Srikanth , Mithani Salima S. , Wilson Lindsay , Wilson Kumanan
Published: March 2021

Background The media play a critical role in informing the public about the pandemic. International travel is a highly contested subject in the media during the COVID-19 pandemic at both the international and national levels. We examined Canadian media reporting on international travel restrictions during the pandemic, how these restrictions aligned with the IHR (2005), and how the narrative around international travel evolved for the pandemic.MethodsWe analysed Canada’s top three national newspapers by circulation, namely – The Globe and Mail, The National Post and The Toronto Star, published between Jan 1, 2020 - May 31, 2020. Our search yielded a total of 378 articles across the three newspapers. Upon removing duplicates and screening the remaining articles, we included a total of 62 articles for the analysis. We conducted a qualitative media content analysis by using the inductive coding approach.ResultsThree major themes were identified within the articles. These included: 1) The role of scientific and expert evidence in implementing travel restrictions; 2) Federal legislation, regulations and enforcement of international travel measures; and 3) Compliance with WHO guidelines in travel restriction policy- and decision-making. The federal government relied on scientific evidence for implementing international travel restrictions. The federal government fully exercised its powers under the Quarantine Act to enforce travel regulations and comply with the IHR (2005). The government embraced rules-based international order by following WHO recommendations on international travel, contributing to delaying border closure and travel restrictions until mid-March.Conclusion The media focussed significantly on international travel related issues during the early phase of pandemic. The dominant media narrative remained the need for earlier travel restrictions against international travel.
An Integrative, Multi-parametric Approach for the Comprehensive Assessment of Microbial Quality and Pollution in Aquaculture Systems
Authors: Stabili Loredana , Salvo Marco Di , Alifano Pietro , Talà Adelfia
Published: March 2021

As the aquaculture sector significantly expanded worldwide in the past decades, the concept of sustainable aquaculture has developed with the challenge of not only maximizing benefits but also minimizing the negative impacts on the environment assuring, at the same time, food security. In this framework monitoring and improving the microbiological water quality and animal health is a central topic. In the present study, we evaluated the seawater microbiological quality in a mariculture system located in a Mediterranean coastal area (Northern Ionian Sea, Italy). We furnished, for the first time, a microbial inventory based on conventional culture-based methods, integrated with the 16S rRNA gene metabarcoding approach for vibrios identification and diversity analyses, and further implemented with microbial metabolic profiling data obtained from the Biolog EcoPlate system. Microbiological pollution indicators, vibrios diversity, and microbial metabolism were determined in two different times of the year (July and December). All microbial parameters measured in July were markedly increased compared to those measured in December. The presence of potentially pathogenic vibrios is discussed concerning the risk of fish disease and human infections. Thus, the microbial inventory here proposed might represent a new multi-parametric approach for the suitable surveillance of the microbial quality in a mariculture system. Consequently, it could be useful for ensuring the safety of both the reared species and the consumers in the light of sustainable, eco-friendly aquaculture management.
Tapping Span Test as a Simple Diagnostic Tool for Patients With Initial-stage Posterior Cortical Atrophy: Short Tapping Span Length Indicates Visuospatial Working Memory Dysfunction
Authors: Funayama Michitaka , Takata Taketo , Nakagawa Yoshitaka , Sunagawa Kosaku , Nakajima Asuka , Kawashima Hiroaki , Mimura Masaru
Published: March 2021

Posterior cortical atrophy is a rare degenerative condition with prominent visuospatial dysfunction which commonly occurs between ages 50 and 65. A diagnosis of posterior cortical atrophy during its initial stage is sometimes challenging and can be delayed because there are currently no established neuropsychological examination methods that can easily be used in clinical settings. In this study, we examined whether the tapping span test is a potential diagnostic tool for posterior cortical atrophy and what impairment the tapping span test is indicative of in this condition. Eight patients with initial-stage posterior cortical atrophy were recruited. Age- and severity-matched individuals with amnesic Alzheimer’s disease (n = 9) were also recruited as a control group. The participants were subjected to the tapping span test and several visuospatial working memory tests. The results of the tapping span and visuospatial working memory tests were worse for the posterior cortical atrophy group when compared with the control group. The results from the tapping span tests were strongly correlated with those from the visuospatial working memory tests. The tapping span test is a simple and potentially useful diagnostic tool for patients with initial-stage posterior cortical atrophy, as it reflects visuospatial working memory function.
Bromine domain protein 4 is an important marker for prognosis of ovarian cancer and tumor immune infiltration
Authors: Chen Chujia , Yang Zhiyong , Zhao Qiuchan , Xu Bangming , Cao Donglin
Published: March 2021

Background

Ovarian cancer (OC) is one of the most common malignant gynecological tumors, but its pathogenesis is unclear. Bromine domain protein 4 (BRD4) is involved in the malignant transformation of cells, as well as the invasion and metastasis of tumor cells. The biological role of BRD4 in ovarian cancer is yet to be determined.
Methods

The differential expression of BRD4 in OC and corresponding normal tissues was evaluated by exploring the Tumor Immune Assessment Resources (TIMER) and the Oncomine database. The correlation between the expression level of BRD4 and the prognosis of OC patients was evaluated using the Kaplan-Meier Plotter database. Using TIMER, we further studied the correlation between BRD4 and tumor immune cell infiltration.
Results

The expression of BRD4 was significantly higher in patients with OC, and high BRD4 expression was closely related to low overall survival rate. The BRD4 expression was associated with the levels of immune markers of macrophages, dendritic cells, neutrophils, and various effector T cells. Taken together, these findings show that BRD4 expression is significantly related to immune infiltration in OC and suggest that BRD4 might play an important role in the immune evasion of OC cells.
Conclusion

The expression level of BRD4 in OC tissues is significantly upregulated, and its high expression is significantly associated with poor prognosis of patients and is closely related to tumor immune infiltration. These results suggest that BRD4 can be used as a prognostic marker and a marker of immune infiltration in OC.
Metabolomics Comparison Between Ovine and Bovine Serum at Mid-lactation
Authors: Su Xiaohu , Zheng Zhong , Zhang Liguo , Bai Urhan , Su Guanghua , Wu Yunxi , Li Guangpeng , Zhang Li
Published: March 2021

The ovine milk owns higher lactoprotein, fat and other solids than bovine milk. However, the mechanism was not fully clear. To discover the specific mechanism, an untargeted metabolomics analyze of serum at mid-lactation by liquid chromagraphy-mass spectrometry (LC-MS) was performed. Then multivariate statistical analysis was carried out to find the specific differences. Final the different abundant metabolites were functionally enrichment by KEGG. In total, 1615 metabolites were detected in serum and 486 were annotated. The the largest metabolic category was lipids and lipid-like molecules (188 metabolites). 412 metabolites were identified as differential metabolites between two groups. KEGG pathway enrichment showed that 18 and 10 functional pathways of differential metabolites were enriched at positive and negative ion mode, separately. Notably, hernandezine, which is a novel AMPK activator, may play a role in the formation of lactoprotein of ovine milk. The results indicated that there may be different biological effects between two species serum. The serum metabolites could make help for the formation of milk.
Identification of the conserved domains of ADP-Glucose Pyrophosphorylase (AGPase) protein in sweetpotato (Ipomoea batatas (L.) Lam.) and its two wild relatives
Authors: Nie Hualin , Kim Sujung , Kim Hohyun , Kim Ji-Seong , Kim Sun-Hyung
Published: March 2021

The conserved domains are defined as recurring units in molecular evolution, which are commonly used to interpret the molecular function and biochemical structure of proteins. The AGPase amino acid sequences of three species from the Ipomoea genus were identified to investigate their physicochemical and biochemical characteristics. The molecular weights (MW), isoelectric point (pI), instability index (II), and grand average of hydropathy (GRAVY) showed considerable differences in each plant. The aliphatic index (AI) values of sweetpotato AGPase proteins were higher in the small subunit than in the large subunit. The AGPase proteins from sweetpotato contain an LbH_G1P_AT_C domain in the C-terminal region and various domains (NTP_transferase, ADP_Glucose_PP, or Glyco_tranf_GTA) in the N-terminal region. On the other hand, most of its two relatives (I. trifida and I. triloba) only contain the NTP_transferase domain in the N-terminal region. These findings suggested that these conserved domains were species specificity and related to the subunit types of AGPase proteins. The study may enable research on the AGPase-related specific characteristics of sweetpotatoes, which do not exist in the other two species, such as starch metabolism and tuberization mechanism.