bluuebunny/crossref_metadata_2025 huggingface dataset:
MRI-derived PRECISE scores for predicting pathologically-confirmed radiological progression in prostate cancer patients on active surveillance
Authors: Caglic Iztok , Sushentsev Nikita , Gnanapragasam Vincent J. , Sala Evis , Shaida Nadeem , Koo Brendan C. , Kozlov Vasily , Warren Anne Y. , Kastner Christof , Barrett Tristan
Published: November 2020

Objectives

To assess the predictive value and correlation to pathological progression of the Prostate Cancer Radiological Estimation of Change in Sequential Evaluation (PRECISE) scoring system in the follow-up of prostate cancer (PCa) patients on active surveillance (AS).

Methods

A total of 295 men enrolled on an AS programme between 2011 and 2018 were included. Baseline multiparametric magnetic resonance imaging (mpMRI) was performed at AS entry to guide biopsy. The follow-up mpMRI studies were prospectively reported by two sub-specialist uroradiologists with 10 years and 13 years of experience. PRECISE scores were dichotomized at the cut-off value of 4, and the sensitivity, specificity, positive predictive value and negative predictive value were calculated. Diagnostic performance was further quantified by using area under the receiver operating curve (AUC) which was based on the results of targeted MRI-US fusion biopsy. Univariate analysis using Cox regression was performed to assess which baseline clinical and mpMRI parameters were related to disease progression on AS.

Results

Progression rate of the cohort was 13.9% (41/295) over a median follow-up of 52 months. With a cut-off value of category ≥ 4, the PRECISE scoring system showed sensitivity, specificity, PPV and NPV for predicting progression on AS of 0.76, 0.89, 0.52 and 0.96, respectively. The AUC was 0.82 (95% CI = 0.74–0.90). Prostate-specific antigen density (PSA-D), Likert lesion score and index lesion size were the only significant baseline predictors of progression (each p < 0.05).

Conclusion

The PRECISE scoring system showed good overall performance, and the high NPV may help limit the number of follow-up biopsies required in patients on AS.

Key Points

• PRECISE scores 1–3 have high NPV which could reduce the need for re-biopsy during active surveillance.

• PRECISE scores 4–5 have moderate PPV and should trigger either close monitoring or re-biopsy.

• Three baseline predictors (PSA density, lesion size and Likert score) have a significant impact on the progression-free survival (PFS) time.
Processing of optical glasses by single, 34 fs pulses in the strong field ionization domain: ablation characteristics and crater morphology
Authors: Andrásik A. , Flender R. , Budai J. , Szörényi T. , Hopp B.
Published: November 2020

The material response of Borofloat, BK7, and B270 glass targets to 34 fs pulses of 800 nm central wavelength is analyzed in the 1–30 J/cm2 fluence domain. The contours of the craters change with the fluence very much the same for all three glasses up to approximately 20 J/cm2, above which the Borofloat and BK7 continue behaving similarly, while bump formation sets on for the B270 glass. Analyzing the contours single-shot ablation thresholds are determined by applying both the conventional diameter regression technique and a multiphoton absorption-based fit to depth data. The ablation threshold values are equal within the 6.1 ± 0.55 J/cm2 domain for the three glasses as well as the three-photon absorption coefficients, which lie in the same magnitude (10–25 cm3/W2). Above the ablation threshold, the diameter values follow logarithmic dependence in the fluence range investigated, reaching similar values around 45 µm at 30 J/cm2 with 51 ± 1 µm 1/e2 beam diameter on the target surface as derived from the diameter regression technique. The onset of plasma formation derived from the changes in the energy reflected from the processed surface is also found to be similar for the three glasses (9.5, 10, and 8.0 J/cm2) in good correlation with the ablation threshold values.
Area-covering postprocessing of ensemble precipitation forecasts using topographical and seasonal conditions
Authors: Friedli Lea , Ginsbourger David , Bhend Jonas
Published: November 2020

Probabilistic weather forecasts from ensemble systems require statistical postprocessing to yield calibrated and sharp predictive distributions. This paper presents an area-covering postprocessing method for ensemble precipitation predictions. We rely on the ensemble model output statistics (EMOS) approach, which generates probabilistic forecasts with a parametric distribution whose parameters depend on (statistics of) the ensemble prediction. A case study with daily precipitation predictions across Switzerland highlights that postprocessing at observation locations indeed improves high-resolution ensemble forecasts, with $$4.5\%$$

4.5
%

CRPS reduction on average in the case of a lead time of 1 day. Our main aim is to achieve such an improvement without binding the model to stations, by leveraging topographical covariates. Specifically, regression coefficients are estimated by weighting the training data in relation to the topographical similarity between their station of origin and the prediction location. In our case study, this approach is found to reproduce the performance of the local model without using local historical data for calibration. We further identify that one key difficulty is that postprocessing often degrades the performance of the ensemble forecast during summer and early autumn. To mitigate, we additionally estimate on the training set whether postprocessing at a specific location is expected to improve the prediction. If not, the direct model output is used. This extension reduces the CRPS of the topographical model by up to another $$1.7 \%$$

1.7
%

on average at the price of a slight degradation in calibration. In this case, the highest improvement is achieved for a lead time of 4 days.
Systematic stability analysis, evaluation and testing process, and platform for grid-connected power electronic equipment
Authors: Zhang Ziqian , Schürhuber Robert , Fickert Lothar , Friedl Katrin , Chen Guochu , Zhang Yongming
Published: November 2020

The proportion of grid-connected power electronic equipment is already large enough to influence the dynamic characteristics of the modern power system. Ensuring the stability of grid-connected power electronic equipment in all relevant situations is one of the foundations for reliable power system operation. In contrast to conventional rotating machines, the stability of power electronic devices mostly depends on the applied control strategy, and a large diversity of different complex control strategies are in practical use. Also, the investigation of stability of such systems needs to take into account the non-linear behaviour of the power electronic equipment. These are the main reasons why the system behavior of grid-connected power electronic equipment cannot be reproduced satisfactorily when aplying a single method of stability analysis, evaluation and testing method. During the last years, faults which led to tripping of converters due to stability problems occurred frequently even though standardized fault compliance tests were performed on these converters. In this paper these stability issues are analyzed. Also, a three-dimensional stability analysis method is suggested in order to comprehensively cover system behavior. The three dimensions are the time/scale dimension, the equipment number dimension and the local or global range of the stability analysis dimension. Based on this three-dimensional framework, this paper proposes a stability evaluation as well as a test process applying a hardware-in-the-loop test concept. Through the verification and testing of the stability of the actual grid-connected power electronic equipment, the method proposed in this paper is verified for up-to-date equipment.
Ninety-five years of observed disturbance-based tree mortality modeled with climate-sensitive accelerated failure time models
Authors: Maringer Janet , Stelzer Anne-Sophie , Paul Carola , Albrecht Axel T.
Published: November 2020

Modeling disturbance-based tree mortality is becoming increasingly important in the discussion of how to adapt forests to climate change and to preserve their ecosystem services and mitigate the risk of economic losses. In this study, we fitted species-specific interval-censored Accelerated Failure Time models for five major tree species to derive the influence of climate, soil, silvicultural measures, stand and tree characteristics on survival times. We coded all disturbance-based mortality causes as events and analyzed 473,501 individual trees distributed across 2248 long-term (1929–2014) forest growth and yield plots in southwestern Germany. We observed different survival probabilities among tree species with Douglas-fir having the lowest survival probability at age 100 years, followed by Norway spruce and Silver fir. Contrastingly, beech and oak had survival probabilities above 0.98 at age 100 years. Most important factor influencing these survival times was climate. Higher summer temperature shortens the survival time of beech, Silver fir and oak, while Norway spruce suffers more from warmer and wetter winters. Beside climatic factors, base saturation showed a significant positive relationship to survival time for all investigated tree species, except for Norway spruce, which had shorter survival times with increasing cation exchange capacity of the soil. Additionally, short-term effects of destabilization after thinning were found. In conclusion, favoring broadleaved tree species, avoiding heavy thinning in older stands and limiting tree age reduce the probability of disturbance-based tree mortality. However, some of the effects found that cause-unspecific mortality modeling has limited potential to describe the mortality–climate change relation.
Balanced truncation of linear time-invariant systems over finite-frequency ranges
Authors: Benner Peter , Du Xin , Yang Guanghong , Ye Dan
Published: November 2020

This paper discusses model order reduction of linear time-invariant (LTI) systems over limited frequency intervals within the framework of balanced truncation. Two new frequency-dependent balanced truncation methods are developed, one is single-frequency (SF)-type frequency-dependent balanced truncation to cope with the cases that only a single dominating point of the operating frequency interval is pre-known, and the other is interval-type frequency-dependent balanced truncation to deal with the case that both the upper and lower bounds of the relevant frequency interval are known a priori. Error bounds for both approaches are derived to estimate the approximation error over a pre-specified frequency interval. In contrast to other error bounds for frequency-weighted or frequency-limited balanced truncation, these bounds are given specifically for the interval under consideration and are thus often sharper than the global bounds for previous methods. We show that the new methods generally lead to good in-band approximation performance, and at the same time provide accurate error bounds under certain conditions. Examples are included for illustration.
Social cybersecurity: an emerging science
Authors: Carley Kathleen M.
Published: November 2020

With the rise of online platforms where individuals could gather and spread information came the rise of online cybercrimes aimed at taking advantage of not just single individuals but collectives. In response, researchers and practitioners began trying to understand this digital playground and the way in which individuals who were socially and digitally embedded could be manipulated. What is emerging is a new scientific and engineering discipline—social cybersecurity. This paper defines this emerging area, provides case examples of the research issues and types of tools needed, and lays out a program of research in this area.
Globalized inexact proximal Newton-type methods for nonconvex composite functions
Authors: Kanzow Christian , Lechner Theresa
Published: November 2020

Optimization problems with composite functions consist of an objective function which is the sum of a smooth and a (convex) nonsmooth term. This particular structure is exploited by the class of proximal gradient methods and some of their generalizations like proximal Newton and quasi-Newton methods. The current literature on these classes of methods almost exclusively considers the case where also the smooth term is convex. Here we present a globalized proximal Newton-type method which allows the smooth term to be nonconvex. The method is shown to have nice global and local convergence properties, and some numerical results indicate that this method is very promising also from a practical point of view.
A large wild salmon stock shows genetic and life history differentiation within, but not between, rivers
Authors: Miettinen Antti , Palm Stefan , Dannewitz Johan , Lind Emma , Primmer Craig R. , Romakkaniemi Atso , Östergren Johan , Pritchard Victoria L.
Published: November 2020

Anadromous salmonid fishes frequently exhibit strong geographic population structuring. However, population genetic differentiation of Atlantic salmon (Salmo salar) at fine geographic scales differs across equivalent spatial extents in different regions. So far, fine-scale genetic differentiation has not been assessed in rivers of the Baltic Sea, a region that contains an evolutionarily distinct Atlantic salmon lineage. Thus, Baltic salmon are currently managed on the river level, without focus on potential genetic structure and diversity within rivers. Here, we used microsatellites to characterize the genetic structure of wild juvenile salmon sampled throughout the interconnected, northern Baltic Tornio and Kalix Rivers. We found genetic differentiation within the two rivers, but not between them: salmon in the upper reaches differed from individuals in the lower reaches, regardless of river system. Further, examining smolts migrating from the river to the sea and adults returning from the sea to spawn, we found an association between the genetic structure and seasonal migration timing. Out-migrating smolts genetically assigned to upper river reaches were older and tended to reach the sea later in the season than smolts from the lower reaches. In contrast, mature adults originating from the upper reaches returned to the river early in the season. Our observation of genetic population structuring between downstream and upstream reaches of the large Tornio and Kalix rivers, and its association with migration timing, implies that careful temporal management of the northern Baltic fisheries would help to preserve the diversity and sustainability of the wild salmon stocks of these rivers.
Mapping the field of research on African higher education: a review of 6483 publications from 1980 to 2019
Authors: Zavale Nelson Casimiro , Schneijderberg Christian
Published: November 2020

Following a global trend, higher education (HE) in Africa has also become a complex enterprise, potentially demanding specific expertise in higher education research. However, despite this, there is a dearth of analysis into the state of research on African HE. This paper seeks to fill this gap by mapping and analysing African HE research. We undertake a systematic review of 6483 articles and books focusing on African HE published from 1980 to 2019 in indexed and non-indexed journals and book-publishers. We particularly examine the evolution of publications, the journals and book publishers, the authors’ affiliations, the researched countries, the publications’ thematic classification, the most prolific authors, and the most influential publications. Based on this analysis, we draw four main conclusions. First, research on African HE is a rather recent phenomenon or has witnessed a recent rise or renewal. Second, a few selected journals and book-publishers, particularly those with a strong regional or international reputation, dominate the field. Third, four communities of researchers are more represented: the community researching teaching and learning issues, the community focusing on structural transformation of HE, the community focusing on the internal organisation of HE and the community focusing on societal engagement of HE. Four, South Africa dominates the field both as home to most of the authors (including the most prolific) and the empirical field of most publications (including the most influential). If South Africa is excluded, African HE research is weak, but some communities are emerging, particularly in West, East and Southern Africa.
The Role of Decision-Making in Psychological Wellbeing and Risky Behaviours in Autistic Adolescents Without ADHD: Longitudinal Evidence from the UK Millennium Cohort Study
Authors: Hosozawa Mariko , Mandy William , Cable Noriko , Flouri Eirini
Published: November 2020

This study examined the development of decision-making and its association with psychological wellbeing and risky behaviours in adolescents with and without autism. Participants included 270 autistic and 9,713 typically developing adolescents. In both samples, those with a diagnosis of attention-deficit/hyperactivity disorder (ADHD) were excluded. Data came from the Millennium Cohort Study, a nationally representative population-based birth cohort. Decision-making was assessed using the Cambridge Gambling Task at ages 11 and 14. Psychological wellbeing (happiness, self-esteem, depressive symptoms and self-harm) and risky/antisocial behaviours were self-reported at age 14. After adjusting for sex, cognitive ability, spatial working memory, socioeconomic status and pubertal status, autistic adolescents showed comparable quality of decision-making to that of their peers at both ages but also a more deliberative decision-making style as they aged. Only in autistic adolescents was this decision-making style associated with positive outcomes.
Effort-Reward Imbalance at Work and Overcommitment in Patients with Acute Myocardial Infarction (AMI): Associations with Return to Work 6 Months After AMI
Authors: Ruile Sarah , Meisinger Christine , Burkhardt Katrin , Heier Margit , Thilo Christian , Kirchberger Inge
Published: November 2020

PurposeStress-related factors influence the adaptation to life after acute myocardial infarction (AMI), including return to work. The goal of this study was to investigate the effect of work-related stress, (expressed by the effort-reward imbalance (ERI) model) on return to work after AMI.MethodsA longitudinal study with AMI patients was conducted in order to assess associations between the independent variables effort, reward, ERI and overcommitment and the outcome return to work after AMI. Return to work was inquired at 6 months follow-up. Logistic regression models were applied in the analysis. The fully-adjusted model included demographic, clinical, social, stress-related and health-related quality of life (HRQOL) covariables.ResultsOf the 346 enrolled patients aged 31 to 82 years, 239 (69.1%) were included in the regression analysis. In the unadjusted model ERI presented an odds ratio (OR) of 1.72 (95% confidence interval (CI) 0.86–3.42). Associations for effort and overcommitment were 0.98 (95% CI 0.83–1.15) and 1.09 (95% CI 0.99–1.18). However, reward showed a significantly inverse association with return to work with an OR of 0.90 (95% CI 0.83–0.99). In the fully adjusted model the OR of ERI decreased to 1.20 (95% CI 0.49–2.96). Effort, reward and overcommitment also showed attenuated ORs without significant results in all models. Diabetes mellitus, current smoking, low physical and low mental HRQOL presented significantly negative relations with return to work.ConclusionsWork-related stress appears less important than HRQOL and resilience in terms of return to work after AMI.
Country-Level Structural Stigma, School-Based and Adulthood Victimization, and Life Satisfaction Among Sexual Minority Adults: A Life Course Approach
Authors: van der Star Arjan , Pachankis John E. , Bränström Richard
Published: November 2020

Country-level structural stigma, defined as prejudiced population attitudes and discriminatory legislation and policies, has been suggested to compromise the wellbeing of sexual minority adults. This study explores whether and how structural stigma might be associated with sexual minorities’ school-based and adulthood experiences of victimization and adulthood life satisfaction. Using a sample of 55,263 sexual minority individuals (22% female; 53% 18–29 years old; 85% lesbian/gay, 15% bisexual) living across 28 European countries and a country-level index of structural stigma, results show that sexual minorities, especially men, reported school bullying in both higher- and lower-stigma countries. Higher rates of school bullying were found among sexual minorities living in higher-stigma countries when open about their identity at school. Past exposure to school bullying was associated with lower adulthood life satisfaction, an association partially explained by an increased risk of adulthood victimization. These findings suggest that sexual minorities living in higher-stigma countries might benefit from not being open about their sexual identity at school, despite previously established mental health costs of identity concealment, because of the reduced risk of school bullying and adverse adulthood experiences. These results provide one of the first indications that structural stigma is associated with sexual minority adults’ wellbeing through both contemporaneous and historical experiences of victimization.
The legitimacy of global accounting rules: a note on the challenges from path-dependence theory
Authors: Pittroff Esther
Published: November 2020

This paper discusses the legitimacy of the convergence of accounting regulation from the view of path-dependence theory. It is argued here that legitimacy of converged accounting rules is almost impossible to achieve because of the path-dependent development of corporate governance systems, which depends on the prevailing norms and beliefs of society. The different elements of corporate governance systems have to be consistent with these values in order to achieve the real convergence of accounting standards. The paper analyses the development of accounting convergence and discusses different convergence strategies from the view of legitimacy theory and path-dependence theory. Finally, the paper presents a hypothetical solution under which real convergence of accounting standards seems possible. The results of the paper are relevant for accounting research, and important to regulators as well, because, by analysing the factors that influence convergence, the paper is able to help us to understand why real convergence of accounting regulation may be difficult to achieve.
Transport of Turbulence Across Permeable Interface in a Turbulent Channel Flow: Interface-Resolved Direct Numerical Simulation
Authors: Chu Xu , Wang Wenkang , Yang Guang , Terzis Alexandros , Helmig Rainer , Weigand Bernhard
Published: November 2020

Turbulence transportation across permeable interfaces is investigated using direct numerical simulation, and the connection between the turbulent surface flow and the pore flow is explored. The porous media domain is constructed with an in-line arranged circular cylinder array. The effects of Reynolds number and porosity are also investigated by comparing cases with two Reynolds numbers ($$Re\approx 3000,6000$$

R
e
≈
3000
,
6000

) and two porosities ($$\varphi =0.5,0.8$$

φ
=
0.5
,
0.8

). It was found that the change of porosity leads to the variation of flow motions near the interface region, which further affect turbulence transportation below the interface. The turbulent kinetic energy (TKE) budget shows that turbulent diffusion and pressure transportation work as energy sink and source alternatively, which suggests a possible route for turbulence transferring into porous region. Further analysis on the spectral TKE budget reveals the role of modes of different wavelengths. A major finding is that mean convection not only affects the distribution of TKE in spatial space, but also in scale space. The permeability of the wall also have an major impact on the occurrence ratio between blow and suction events as well as their corresponding flow structures, which can be related to the change of the Kármán constant of the mean velocity profile.
Microbial population dynamics during traditional production of Mabisi, a spontaneous fermented milk product from Zambia: a field trial
Authors: Groenenboom Anneloes E. , Shindano John , Cheepa Nachimuka , Smid Eddy J. , Schoustra Sijmen E.
Published: November 2020

Mabisi is a fermented milk product, traditionally produced in a calabash by uncontrolled fermentation. Due to high costs and a reduced availability of calabashes, nowadays plastic containers are also used for Mabisi production. However, the effect of this change in production practice on the properties of the product has not been documented. Therefore, we aimed at determining the effect of fermentation vessels and types of back-slopping on acidification and microbial communities during fermentation. A series of fifteen experiments using two types of fermentation vessels (plastic buckets and calabashes) in combination with different types of back-slopping (no back-slopping, passive back-slopping, and active back-slopping) were set up at a field site in rural Zambia. In each of the fifteen fermentations we analysed acidification rate of traditional Mabisi fermentation and bacterial diversity over time. No significant difference was found in terms of microbial diversity during and at the end of fermentation between fermentations performed in buckets or previously used calabashes. Bacterial communities in general decreased in diversity over time, where the drop in pH correlated with a decrease in Shannon Index. In case of active back-slopping, the pH drop started right after inoculation while in the no back-slopping and passive back-slopping fermentations, there was a clear lag phase before acidification started. All experimental series resulted in a microbial community dominated by Lactococcus lactis and a Shannon Index, as a measure for diversity, between 0.6 and 2.0. The use of plastic buckets for Mabisi fermentation can be a valuable alternative to the use of calabashes as this study showed no biological and physico-chemical differences between Mabisi resulting from both fermentation vessels, although the reason for perceived differences should be further investigated.
Upregulation of miRNA-23a-3p rescues high glucose-induced cell apoptosis and proliferation inhibition in cardiomyocytes
Authors: Wu Fang , Wang Feng , Yang Qian , Zhang Yawen , Cai Ke , Liu Lian , Li Shuchun , Zheng YuanZheng , Zhang Jialing , Gui Yiting , Wang Youhua , Wang Xu , Gui Yonghao , Li Qiang
Published: November 2020

Maternal hyperglycemia potentially inhibits the development of the fetal heart by suppressing cardiomyocyte proliferation and promoting apoptosis. Different studies have indicated that miRNAs are key regulators of cardiomyocyte proliferation, differentiation, and apoptosis and play a protective role in a variety of cardiovascular diseases. However, the biological function of miRNA-23a in hyperglycemia-related cardiomyocyte injury is not fully understood. The present study investigated the effect of miRNA-23a-3p on cell proliferation and apoptosis in a myocardial injury model induced by high glucose. H9c2 cardiomyocytes were exposed to high glucose to establish an in vitro myocardial injury model and then transfected with miRNA-23a-3p mimics. After miRNA-23a-3p transfection, lens-free microscopy was used to dynamically monitor cell numbers and confluence and calculate the cell cycle duration. CCK-8 and EdU incorporation assays were performed to detect cell proliferation. Flow cytometry was used to measured cell apoptosis. Upregulation of miRNA-23a-3p significantly alleviated high glucose-induced cell apoptosis and cell proliferation inhibition (p < 0.01 and p < 0.0001, respectively). The cell cycle of the miRNA-23a-3p mimics group was significantly shorter than that of the negative control group (p < 0.01). The expression of cell cycle–activating and apoptosis inhibition-associated factors Ccna2, Ccne1, and Bcl-2 was downregulated by high glucose and upregulated by miRNA-23a-3p overexpression in high glucose-injured H9c2 cells. miRNA-23a-3p mimics transfection before high glucose treatment had a significantly greater benefit than transfection after high glucose treatment (p < 0.0001), and the rescue effect of miRNA-23a-3p increased as the concentration increased. This study suggests that miRNA-23a-3p exerted a dose- and time-dependent protective effect on high glucose-induced H9c2 cardiomyocyte injury.
Early snowmelt reduces aphid abundance (Aphis asclepiadis) by creating water-stressed host plants (Ligusticum porteri) and altering interactions with ants
Authors: Mooney Emily , Mullins Maria , Den Uyl James , Trail Samantha , Nguyen Phuong , Owens Janel , Godtfredsen Elsa , Heschel Shane
Published: November 2020

Declining snow cover is reshaping ecological communities. Early loss of snow cover initiates changes in key interactions that mediate herbivore abundance, i.e., top-down and bottom-up effects. In this study, we used a field experiment to test the effects of host plant water stress and phenology on the multitrophic interactions that determine aphid abundance. The aphid, Aphis asclepiadis, in our study system colonizes the flowering stalks of the host plant Ligusticum porteri and relies on a protection mutualism with ants. We added snow and water to replicate host plants and tested for a variety of phenological and physiological responses to these treatments. Relative to host plants in ambient conditions, both water and snow addition reduced key signals of water stress (senescence and abscisic acid levels) and increased seed set. While aphid colonies were generally larger with reduced host plant water stress, the ant–aphid mutualism interacted with plant quality in complex ways. Without ant tending, we did not detect differences in aphid colony growth with host plant treatment. When tended by ants, aphid colony growth was greatest on host plants with snow addition. Host plant quality also altered the benefits exchanged in this mutualism. Ant-tended colonies hosted by plants with snow addition produced honeydew enriched in trehalose, which may have decreased both ant and natural enemy abundance. Our results suggest that early loss of snow reduces aphid abundance by creating low-quality, water-stressed host plants, and this effect may be exacerbated by natural enemies and the costs of ant attendance.
The psychometric properties and clinical utility of the Norwegian versions of the deliberate self-harm inventory and the inventory of statements about self-injury
Authors: Vigfusdottir Johanna , Dale Karl Yngvar , Gratz Kim L. , Klonsky E. David , Jonsbu Egil , Høidal Reidun
Published: November 2020

Deliberate self-harm (DSH) is a widespread transdiagnostic health problem with increasing prevalence among adolescences, and young adults. It is therefore essential to effectively chart the epidemiology of DSH, as well as to assess the efficacy of interventions designed to modify this behavior. The aim was to translate and analyze the psychometric properties of the Norwegian versions of two instruments designed to assess DSH: the Deliberate Self-harm Inventory (DSHI) and the Inventory of Statements About Self-Injury (ISAS), as well as to assess the prevalence of DSH within a nonclinical Norwegian adult population. Of the 402 participants who completed a questionnaire packet comprising the DSHI, ISAS, general questions about DSH, and other related measures, 30.6% reported some form of DSH. Those with a history of DSH reported greater difficulties with emotion regulation than those without. Participants with and without a history of DSH did not differ in unrelated constructs, including social desirability. The frequency of specific DSH behaviors was in accordance with previous research, with cutting being the most frequent. The factor structure of DSH functions in the Norwegian ISAS was generally comparable to the factor structure of the English version. Overall, results indicate that: a) the Norwegian versions of the DSHI and ISAS behave as expected and in accordance with prior research in other languages and other populations, and b) both the DSHI and ISAS have high internal consistency and adequate construct, convergent, and discriminant validity, and may be applied to evaluate DSH in adult Norwegian populations.
Menatanthus mosbruggeri gen. nov. et sp. nov. – A flower with in situ pollen tetrads from the Paleocene maar lake of Menat (Puy-de-Dôme, France)
Authors: Uhl Dieter , Paudayal Khum N. , Hervet Sophie , El Atfy Haytham
Published: November 2020

The Paleocene Fossil-Lagerstätte Menat in France is well known for its wealth of outstandingly well preserved fossil insects and plants. Despite being known for more than a century, the palaeoflora, which is regarded as typical for the late Thanetian by some authors, has largely been neglected since the 1940s. New excavations and surveys yielded exceptionally well-preserved plant material, including a minute, heptamerous flower bearing in situ pollen tetrads, comparable to tetrads of the modern ericacean genusKalmiaL, in its anthers. The only known modern ericacean genus which is characterised by heptamerous flowers isBejariaMutis ex L., a basal relative of the tribe Phyllodoceae within Ericaceae, which also includes the genusKalmiain a relatively basal position. However, heptamerous flowers also occur very rarely (mostly interpreted as teratologies) in a number of other modern Ericaceae, but also in various other modern angiosperm families. Due to the unique combination of a heptamerous flower withKalmia-type pollen tetrads within the anthers, the new taxonMenatanthus mosbruggerigen. nov. et sp. nov. is erected. The lack of morphological data from the flower itself and the fact that comparable pollen tetrads can be produced by a number of modern families, however, prevent an assignment of the new taxon to any known angiosperm family.
Impact of machining-induced surface defects on the edge formability of commercially pure titanium sheet at room temperature
Authors: Kwame J. S. , Yakushina E. , Blackwell P.
Published: November 2020

Despite the good properties of titanium, which have drawn the interest of various industries over the years, one of the major drawbacks of this material is its poor machinability. This has largely been attributed to its low thermal conductivity and elastic modulus. The ability to attain the optimum sheet edge performance during forming is dependent on the quality of the edges produced. Also, the demanding nature of aerospace part design has provoked the interest of both industry and academia to continually explore avenues tailored at enhancing part performance. The sort of edge surface integrity produced for aerospace part fabrication thus becomes a vital consideration in the quest to ensuring prime performance of components. This work seeks to study the influence of different machining-induced surface defects on the sheet edge performance of CP-Ti (grade 2) at room temperature. Hole expansion test was used to assess the edge surface formability of CP-Ti with different machining-induced edge defects. The research found that machining-induced surface defects act as stress concentration sites during the hole expansion test and have a major impact on the material flow. Electro-discharge machined edges were observed to exhibit high edge formability compared to laser and abrasive water jet cut edges due to the impact of machining-induced microstructural changes.
The Patronage Dilemma: Allison Davis's Odyssey from Fellow to Faculty
Authors: Masghati E.
Published: November 2020

This article analyzes the role of the Julius Rosenwald Fund in shaping the career of W. Allison Davis, a distinguished anthropologist who became the first African American appointed to the faculty of a mostly white university. From 1928 to 1948, the Rosenwald Fund ran an expansive fellowship program for African American intellectuals, which, despite its significance, remains largely unexamined in the scholarly literature. Davis tied his academic aspirations to Rosenwald Fund support, including for his early research and the terms of his faculty appointment. His experiences illustrate the dynamics inclusion and exclusion of African Americans in the academy; paternalistic promotion and strategic denial functioned as two sides of the same coin. Spotlighting Davis's negotiations, this article establishes how presumptions of racial inferiority guided Rosenwald patronage and demonstrates the extent to which the principles of meritocracy and expertise remained secondary concerns for those interested in cultivating African American intellectuals.
Are your gains threat or chance for me? A social comparison perspective on idiosyncratic deals and coworkers' acceptance
Authors: Zhang Xiaoyan , Wu Wenbing , Wu Wen , Zhang Yihua , Xia Yuhuan
Published: November 2020

Idiosyncratic deals (i-deals) refer to customized work arrangements and employment conditions employees negotiate with employers. Significant scholarly attention has been paid to understand the responses of i-deals' recipients. However, little attention has been paid to coworkers' reactions to the i-deals. This study examines how coworkers react to focal employees' i-deals. We tested our hypotheses with a sample of 253 employee–coworker pairs and found that coworkers are more likely to accept focal employees' flexibility i-deals than development i-deals. Specifically, we found that coworkers view focal employees' development i-deals as more threatening to their status than flexibility i-deals, and status threat mediates the relationship between development i-deals and coworkers' acceptance. In addition, flexibility i-deals increase coworkers' perception of obtaining future i-deals more than development i-deals, and this perception mediates the relationship between flexibility i-deals and coworkers' acceptance. Furthermore, the results show that coworkers' relative leader–member exchange moderates the above relationships.
Relationship between CEO's personality and company's entrepreneurial orientation: the case of SMEs
Authors: Verdú-Jover Antonio J. , Estrada-Cruz Marina , Rodríguez-Hernández Noelia , Gómez-Gras José M.
Published: November 2020

Entrepreneurial orientation (EO) is a key factor in the creation and development of companies. This study examines the CEO's personal background (personality, proactivity and resistance to change) and its influence on the EO of the organization to determine which factors enhance or weaken EO. We achieve this goal through quantitative research, developing a structural equations model with partial least squares to analyse a sample of 358 Spanish SMEs from different sectors. The results suggest that specific personality dimensions exert substantial influence on the organization's EO. We also analyse individual proactivity and resistance to change as conduits for the effect of personality dimensions on the company's EO.
The Wald Test of Common Factors in Spatial Model Specification Search Strategies
Authors: Juhl Sebastian
Published: November 2020

Distinguishing substantively meaningful spillover effects from correlated residuals is of great importance in cross-sectional studies. Both forms of spatial dependence not only hold different implications for the choice of an unbiased estimator but also for the validity of inferences. To guide model specification, different empirical strategies involve the estimation of an unrestricted spatial Durbin model and subsequently use the Wald test to scrutinize the nonlinear restriction of common factors implied by pure error dependence. However, the Wald test’s sensitivity to algebraically equivalent formulations of the null hypothesis receives scant attention in the context of cross-sectional analyses. This article shows analytically that the noninvariance of the Wald test to such reparameterizations stems from the application of a Taylor series expansion to approximate the restriction’s sampling distribution. While asymptotically valid, Monte Carlo simulations reveal that alternative formulations of the common factor restriction frequently produce conflicting conclusions in finite samples. An empirical example illustrates the substantive implications of this problem. Consequently, researchers should either base inferences on bootstrap critical values for the Wald statistic or use the likelihood ratio test which is invariant to such reparameterizations when deciding on the model specification that adequately reflects the spatial process generating the data.
Ordinary Patterns in an Extraordinary Crisis: How International Relations Makes Sense of the COVID-19 Pandemic
Authors: Johnson Tana
Published: November 2020

The customary prescription for handling “problems without passports” is to work through international intergovernmental organizations (IGOs), act collectively for humanity's future, and build up specialized knowledge. But around the world, patterns from the initial months of the COVID-19 pandemic defied the prescription. IGOs were blamed, narrow or short-term interests were prioritized, and divided reactions to experts were on display. International Relations (IR) scholarship helps explain why: (1) research on bureaucracy and institutional design examines the challenge of making IGOs accountable to member-states but also insulated from them; (2) research on delegation and socialization explores commonplace problems involving time-inconsistency and credible commitments; and (3) research on epistemic communities and anti-elitism describes the rationale and fears of permitting public policy to be guided by unelected experts. The initial months of the COVID-19 pandemic reflect how the world can look when it lacks resolute leadership to overcome commonplace aversions to IGOs, to broader or longer-term interests, and to experts. Yet while IR scholarship makes sense of these patterns, it does not say enough about why resolute leadership wanes, or what to do about IGO performance when it does. Answers to such questions are crucial not only for recovering from the COVID-19 crisis, but for dealing with whatever global crises lie ahead.
Best Practices in Dementia Care: A Review of the Grey Literature on Guidelines for Staffing and Physical Environment in Long-Term Care
Authors: Seetharaman Kishore , Chaudhury Habib , Kary Michael , Stewart Jennifer , Lindsay Barbara , Hudson Mariana
Published: November 2020

In its first national strategy on dementia, the Government of Canada has highlighted the need to improve quality of care for individuals living with dementia, with emphasis on following best practices and evidence in care delivery and providing care staff access to education and training. It is also known that the design of the physical environment of care homes is integral to the care experience of individuals living with dementia. Therefore, this study aims to identify the best national and international practices implemented in care homes for people living with dementia in: (1) education, training, staffing, and care practices; and (2) environmental design and physical infrastructure, through the review of relevant grey literature. This article highlights key recommendations for improving the quality of care for residents living with dementia in care homes, such as: (1) facilitating translation of training into practice, (2) maintaining consistent staffing levels, and (3) designing care homes to facilitate wayfinding, accessibility, safety, comfort, appropriate sensory stimulation, familiarity, and homelikeness. The findings from this review are expected to inform the development of guidelines for a provincial dementia-friendly care home designation program and various advocacy efforts to help achieve the objectives of the national strategy on dementia.
Inhibitory Control of Adjacent Finger Movements while Performing a Modified Version of the Halstead Finger Tapping Test: Effects of Age, Education and Sex
Authors: Prigatano George P. , de Oliveira Sandro Barbosa , Goncalves Carlos Wellington Passos , Denucci Sheila Marques , Pereira Roberta Monteiro , Braga Lucia Willadino
Published: November 2020

Objective:

Selective motor inhibition is known to decline with age. The purpose of this study was to determine the frequency of failures at inhibitory control of adjacent finger movements while performing a repetitive finger tapping task in young, middle-aged and older adults. Potential education and sex effects were also evaluated.

Methods:

Kinematic recordings of adjacent finger movements were obtained on 107 healthy adults (ages 20–80) while they performed a modified version of the Halstead Finger Tapping Test (HTFF). Study participants were instructed to inhibit all finger movements while tapping with the index finger.

Results:

Inability to inhibit adjacent finger movements while performing the task was infrequent in young adults (2.9% of individuals between 20 and 39 years of age) but increased with age (23.3% between the ages of 40 and 59; 31.0% between ages 60 and 80). Females and males did not differ in their inability to inhibit adjacent finger movements, but individuals with a college education showed a lower frequency of failure to inhibit adjacent finger movements (10.3%) compared to those with a high school education (28.6%). These findings were statistically significant only for the dominant hand.

Conclusion:

Selective motor inhibition failures are most common in the dominant hand and occur primarily in older healthy adults while performing the modified version of the HFTT. Monitoring selective motor inhibition failures may have diagnostic significance.
Association between mustard oil consumption and BMI in India
Authors: Chhajed Rutuja , Thomas Tinku , Swaminathan Sumathi , Kurpad Anura V , Mani Indu
Published: November 2020

Objective:

This study examined the association between predominant vegetable oil consumed and BMI of adult women and men in India, with emphasis on predominant consumption of mustard oil.

Design:

Two nationally representative data, the consumer expenditure survey of National Sample Survey Office (NSSO)-68th round (2011–2012) for food consumption and National Family Health Survey-4 (2015–2016) for weight status, were analysed. Data from both surveys were combined by matching households through common matching variables (‘family size’, ‘religion’, etc.) using Nearest-Neighbour Hot-Deck matching. The association of overweight/obesity with predominant mustard oil consumption in the household was examined using logistic regression adjusted for confounders. The NSSO reports household consumption of mustard, groundnut, coconut, refined oils (sunflower, safflower, soyabean) and all other edible oils.

Setting:

Two nationally representative surveys from India.

Participants:

Total of 638 445 women and 92 312 men, respectively.

Results:

Mustard oil was the most predominantly consumed oil (51 %) followed by refined oils (32·4 %). Prevalence of overweight/obesity in women and men was lower in households with predominant mustard oil consumption (17 and 15 %)v. all other refined and other oils combined (27 and 26 %). The adjusted OR for predominant mustard oil use was 0·88 (95 % CI 0·86, 0·87) for women and 0·80 (95 % CI 0·76, 0·83) for men. A similar analysis with predominant groundnut oil consumption showed no association with overweight/obesity.

Conclusions:

The data from a large national level survey suggest an inverse association between mustard oil consumption and overweight/obesity which needs to be explored with further research studies.