Spermiogram changes in patients with mumps orchitis
Authors: Roganović Tatjana , Krivokuća Vladimir 
Published: July 2014

&lt;p&gt;&lt;strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 1159.96px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.15752);&quot; role=&quot;presentation&quot;&gt;Introduction&lt;/span&gt;&lt;/strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 213.44px; top: 1159.96px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.06758);&quot; role=&quot;presentation&quot;&gt;&lt;strong&gt;.&lt;/strong&gt; Mumps is a systemic viral infection characterized by swelling of salivary glands, especially &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 1179.96px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.106);&quot; role=&quot;presentation&quot;&gt;the parotid glands. Gonads, meninges, pancreas and other organs may also be affected. The aim of this &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 1199.96px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.13721);&quot; role=&quot;presentation&quot;&gt;study was to analyze clinical and ultrasound characteristics of mumps orchitis, as well as to analyze &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 1219.96px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.07609);&quot; role=&quot;presentation&quot;&gt;spermiogram in patients treated for mumps orchitis in Infectious Diseases Clinic during mumps epidemic &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 1239.96px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.06632);&quot; role=&quot;presentation&quot;&gt;from October 2011 to December 2012.&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 1269.41px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.16235);&quot; role=&quot;presentation&quot;&gt;Methods&lt;/span&gt;&lt;/strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 185.931px; top: 1269.41px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.14274);&quot; role=&quot;presentation&quot;&gt;&lt;strong&gt;.&lt;/strong&gt; The study included 90 patients with mumps orchitis. We analyzed clinical and laboratory &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 117.728px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.10118);&quot; role=&quot;presentation&quot;&gt;parameters, ultrasound testicular changes (one month after the infection) and spermiogram (six months &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 137.728px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.08905);&quot; role=&quot;presentation&quot;&gt;after the infection).&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 167.178px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.15009);&quot; role=&quot;presentation&quot;&gt;Results&lt;/span&gt;&lt;/strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1166.69px; top: 167.178px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.07793);&quot; role=&quot;presentation&quot;&gt;&lt;strong&gt;.&lt;/strong&gt; The average age of patients was 21.4 years. In every third patient orchitis occurred in the course &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 187.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.07761);&quot; role=&quot;presentation&quot;&gt;of parotitis, and for the rest of the patients orchitis occurred after parotitis. Orchitis was unilateral in 84% &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 207.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.07415);&quot; role=&quot;presentation&quot;&gt;of the patients. Ultrasound testicular changes were present in 74.4% of the patients, and in 68.9% of them &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 227.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.07403);&quot; role=&quot;presentation&quot;&gt;changes were unilateral. The average CRP value was 80.7 mg/L and it was significantly (p=0.014) higher &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 247.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.13955);&quot; role=&quot;presentation&quot;&gt;in patients with bilateral orchitis. The average number of spermatozoids was higher in patients with &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 267.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.11362);&quot; role=&quot;presentation&quot;&gt;unilateral orchitis than in patients with bilateral orchitis and the difference was statistically significant &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 287.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.10948);&quot; role=&quot;presentation&quot;&gt;(p=0.011). Three patients with bilateral orchitis had azoospermia. Semen volume was below reference &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 307.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.12988);&quot; role=&quot;presentation&quot;&gt;limit in 58.8% of patients with unilateral orchitis, while the results for patients with bilateral orchitis&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 327.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.10265);&quot; role=&quot;presentation&quot;&gt;were insufficient. There was no statistically significant difference (p=0.100) in sperm motility between &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 347.177px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.11466);&quot; role=&quot;presentation&quot;&gt;patients with unilateral and bilateral orchitis.&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 376.627px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.14596);&quot; role=&quot;presentation&quot;&gt;Conclusion&lt;/span&gt;&lt;/strong&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1197.25px; top: 376.627px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.08326);&quot; role=&quot;presentation&quot;&gt;. Patients with severe clinical features (bilateral orchitis) had more distinct changes in semen &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 396.626px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.14067);&quot; role=&quot;presentation&quot;&gt;analysis. It is recommended to enable cryopreservation of sperm immediately after the diagnosis of &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 1110.24px; top: 416.626px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.09115);&quot; role=&quot;presentation&quot;&gt;orchitis, especially bilateral, as a possible solution in case of infertility.&lt;/span&gt;&lt;/p&gt;