bluuebunny/crossref_metadata_2025 huggingface dataset:
YAŞLI BİREYLER İÇİN GELENEKSEL YAPILARIN ERİŞİLEBİLİRLİK DEĞERİ ÜZERİNE BİR İNCELEME: MALATYA BEŞKONAKLAR EVİ
Authors: AKÇA Meryem , AKYILDIZ Nihal Arda
Published: November 2022

Kentlerin ilk yerleşim alanları olarak kabul gören geleneksel yerleşim alanlarında sürdürülen sosyal yaşam, fiziki çevreyle yakından ilişkilidir. Geleneksel yerleşim alanları, kentsel planlama içinde kimi zaman merkeze alınmış kimi zaman da kent merkezinden oldukça uzakta bırakılmıştır. Tüm kent kullanıcıları gibi hareket kısıtlılığına sahip yaşlı kullanıcıların da kentin her noktasına erişiminin önemi, sosyal yaşamın tartışılmaz bir gerçeğidir. Bu nedenle nüfus yapısı içinde hatırı sayılır orana sahip olan bu kent kullanıcılarının, sosyal yaşama katılımları ve mekânsal konfor düzeylerinin arttırılmasını sağlayan erişilebilirlik standartlarının önemine dikkat çekmek gerekmektedir. Erişilebilirliğin ulusal ve uluslararası standartlarla ortaya koyduğu ilkeler, tüm bireylerin eşit koşullarda, kesintisiz, sağlıklı ve güvenli şekilde yaşamlarını sürdürebilmeleri için mekânsal düzenlemeler yanında toplumsal yaşamın sürdürülebilirliği açısından da büyük önem arz etmektedir. Kentin geleneksel yerleşim alanlarında da kullanıcılarının tüm hizmetlere kolaylıkla erişilebilmeleri için yapılacak düzenlemeler, yaş almakta olan bireylerin gündelik yaşam katılımlarını arttırmada ve sosyo-kültürel yaşamı desteklemede önemli yer tutmaktadır.

Çalışma bu anlamda ele alınarak kentlerin geleneksel yerleşim alanlarındaki erişilebilirlik düzeyi yanında hareket kısıtlılığına sahip yaşlı kent kullanıcılarının karşılaştığı sorunlara dikkat çekmeyi amaçlanmıştır. Bu bağlamda konunun irdelenmesi için seçilen Malatya ilinde yer alan Beşkonaklar Evi ve çevresinin erişilebilirlik standartlarını ne oranda karşıladığı incelenmiş ve yerinde yapılan analizlerle erişilebilirlik konusunun yaşlı kent kullanıcıları için öneminin ortaya konması hedeflenmiştir.
TÜRKİYE’DE AİLE EĞİTİMİ ALANINDA YAZILMIŞ LİSANSÜSTÜ TEZLERİN İÇERİK ANALİZİ YÖNTEMİYLE İNCELENMESİ
Authors: ÖZTÜRK Nursena , PARLAR Hanifi
Published: November 2022

İnsanların hayatlarında büyük bir rol oynayan aile kurumu yapısal özellikleri, işlevleri ve içinde bulundurduğu ilişkiler dâhil birçok konu açısından farklı yaklaşımlar tarafından yıllar boyunca incelenmiştir. Bu araştırmalar aile kurumunu incelemeye çalışmakta ve araştırmalar sonucu elde edilen bulgular uygulamalı alanlarda kullanılmaktadır. Aile danışmanlığı ve eğitimi de bu alanlardan birisidir. Ülkemizde aile kavramına verilen değer azımsanamayacak kadar çoktur. Bu çalışma, bu denli değerli ve önemli görülen aile kurumunun eğitimi hakkında akademik alanda ne tür çalışmalar yapılıyor, nelere ihtiyacımız var ve daha birçok soruya cevap aramış olan lisansüstü tezlerin sistematik bir özetini oluşturuyor. Çalışmanın amacı, Türkiye’de aile eğitimi alanında yazılmış olan lisansüstü tezlerin incelenmesidir. Yüksek Öğretim Kurulu Tez Merkezi veri tabanında yapılan tarama sonucunda aile eğitimi ile ilgili yazılmış toplam 28 adet tez olduğu görülmüştür. Etik kurallar gereği izinli olmayan 5 adet tez çalışmaya dâhil edilmemiş ve izinli olan toplam 23 tez ile çalışma sürdürülmüştür. Bu tezlerden 20 tanesinin yüksek lisans seviyesinde, 6 tanesinin doktora seviyesinde ve 2 tanesinin ise tıpta uzmanlık seviyesinde yazıldığı görülmüştür. Tezlerin hepsi Türkçe dilinde yayımlanmışlardır. Nitel araştırma yöntemlerinden biri olan içerik analizi yöntemiyle hazırlanan bu çalışmada 1998 – 2019 yılları arası yazılan tezler çeşitli kriterlere göre gruplandırılmış ve analiz edilmiştir. Yapılan analizler sonucu en çok lisansüstü tezin eğitim bilimleri enstitüsünde hazırlandığı, cinsiyet dağılımına bakıldığında en çok kadın yazarların bu konuda tez yayımladığı, tezlerin ağırlıklı olarak doçent doktor unvanına sahip bilim insanları danışmanlığında hazırlandığı, tezlerin en çok Eskişehir ve Ankara illerindeki üniversitelerde okuyan öğrenciler tarafından yazıldığı ve tezlerin en çok özel eğitim ana bilimdalında gerçekleştiği görülmüştür. Ayrıca kaynakçalar incelendiğinde Türkçe, İngilizce ve Almanca kaynaklardan yararlanıldığı analiz edilmiştir. Aile danışmanlığı ve eğitiminin ülkemizde henüz 40 yıllık bir geçmişe sahip olması sebebiyle yapılan çalışmaların günümüze kadar en çok problem yaşanan alanlarda olduğu görülmüştür. Ancak son dönemlerde aile kavramının değişmeye başlaması ve yeni aile türlerinin oluşmaya başlamasıyla birlikte bu ailelere gereken desteği sağlamak ve yardım etmek amacıyla üniversitelerde ders olarak açılması hatta bazı üniversitelerde yüksek lisans programı olarak okutulması alanın daha sistemli ve bilimsel bir geleceğe sahip olduğunu gösteriyor.
Integrated machine learning and GIS-based bathtub models to assess the future flood risk in the Kapuas River Delta, Indonesia
Authors: Sampurno Joko , Ardianto Randy , Hanert Emmanuel
Published: November 2022

As more and more people live near the sea, future flood risk must be properly assessed for sustainable urban planning and coastal protection. However, this is rarely the case in developing countries where there is a lack of both in-situ data collection and forecasting tools. Here, we consider the case of the Kapuas River Delta (KRD), a data-scarce delta on the west coast of Borneo Island, Indonesia. We assessed future flood risk under three climate change scenarios (RCP2.6, RCP4.5, and RCP8.5). We combined the multiple linear regression and the GIS-based bathtub inundation models to assess the future flood risk. The former model was implemented to model the river's water-level dynamics in the KRD, particularly in Pontianak, under the influence of rainfall changes, surface wind changes, and sea-level rise. The later model created flood maps with inundated areas under a 100-year flood scenario, representing Pontianak's current and future flood extent. We found that about 6.4%–11.9% more buildings and about 6.8%–12.7% more roads will be impacted by a 100-year flood in 2100. Our assessment guides the local water manager in preparing adequate flood mitigation strategies.
The eco-friendly treatment of rubber industry effluent by using adsorbent derived from Moringa oleifera bark and Pseudomonas sp, cultured from effluent
Authors: Das Joydeep , Mondal Abhijit , Biswas Srijit , Nag Soma
Published: November 2022

Rubber processing generates a large volume of wastewater containing rubber latex residues and chemicals. Remediation of the wastewater needs a cost-effective and environment-friendly treatment method. For this study, Moringa oleifera stem bark and Pseudomonas sp. bacteria were used for adsorption and microbial treatment of the effluent. The adsorbent surface was mostly amorphous with crystallinity index 37.9 % and the BET surface area was 6.622 m2/g. FTIR analysis indicated involvement of O-H stretching, ketone α, β- unsaturated, C-H stretching, carboxylic acid and derivatives O-C stretching functional groups in the adsorption process. The assessment of the above two agents was based on their reduction capabilities of the toxic parameters, such as total suspended and dissolved solids, total solids, biological and chemical oxygen demand, sulphate, ammonium, dissolved oxygen, phosphate, pH, electrical conductivity, turbidity, and oxidation reduction potential from the wastewater. A comparative study of the present work revealed that both the agents were effective in reduction of most of the above parameters below the safe discharge limits. However, the adsorption using Moringa oleifera stem bark was better compare to the biodegradation by Pseudomonas sp. bacteria. The main challenges that typically accompany biodegradation include microbe handling and a lower removal percentage than adsorption.
PLANEJAMENTO E DESENVOLVIMENTO DE ATIVIDADES CRIATIVAS NO ENSINO REMOTO SOBRE SAÚDE OCULAR: RELATO DE EXPERIÊNCIA
Authors: Thayná Rodrigues Honorato Stephani , De Oliveira Suelen Ferreira , Karine de Macêdo Leopoldino Sâmella , Allana Conceição Macena Fernandes Narjilla , Layse Silva Rosado Viviane , Christiane de Azevedo Machado Flávia
Published: November 2022

Introdução: Propostas pelos docentes do Departamento de Enfermagem da UFRN, as metodologias ativas foram cultivadas entre os períodos letivos de forma a dinamizar conteúdos que normalmente carregam um grande acervo teórico para serem aprendidos. Além disso, promovem habilidades na formação dos estudantes, tais como: proatividade, liderança, trabalho em equipe, entre outros. Objetivo: Este relato de experiência objetiva descrever o planejamento e desenvolvimento de uma atividade criativa no ensino remoto sobre saúde ocular. Metodologia: É um estudo descritivo derivado da disciplina de “Atenção Integral à Saúde do Adulto I”, sob forma de sala invertida e vivenciado por discentes da graduação em Enfermagem do 5.º período da Universidade Federal do Rio Grande do Norte. Resultados: É um estudo descritivo derivado da disciplina de ‘Atenção Integral à Saúde do Adulto I’, sob forma de sala invertida e vivenciado por discentes da graduação em Enfermagem do 5.º período da Universidade Federal do Rio Grande do Norte. Conclusões: Pretende-se contribuir e incentivar o uso de metodologias ativas de forma que o discente construa sua autonomia em potencial, necessária para que se tome a frente da sala de aula, além de construir habilidades de ensino para sua futura atuação profissional.
A ANÁLISE DO CLIMA ESCOLAR COMO PARADIGMA PARA UM NOVO CUIDADO
Authors: De Azevedo Machado Flávia Christiane , Diniz Papa Thomas , Ferreira de Oliveira Suelen , Pinheiro Suassuna Alice , Loos Félix Giovanni
Published: November 2022

Introdução: O clima escolar é a percepção do estudante sobre a instituição no tocante às relações interpessoais, infraestrutura, engajamento comunitário, cogestão, entre outros. Objetivo: caracterizar o clima escolar a partir da percepção dos estudantes, evidenciando as dimensões mais frágeis e as mais estabelecidas. Metodologia: Desenvolveu-se estudo transversal com 129 estudantes matriculados no ano de 2018 no segundo ano do ensino médio em escolas estaduais de Natal/RN. Esses responderam a um questionário para identificação do perfil socioeconômico e clima escolar. Foram calculadas as frequências e medidas de tendência central das variáveis. Resultados: Cerca de 80% dos estudantes concordaram gostar estar na escola ou sentir ter bons amigos nela; 70% afirmam ser boa a relação entre todos os atores da escola; 67,20% sentem que quem trabalha na escola gosta do que faz. Todavia, 40% dos alunos não sentem orgulho da escola, 32% concordaram que todos participam das tomadas de decisões importantes na escola e 53% disseram sentir-se seguros na escola. Conclusões: Conclui-se que Gestão & Transparência e a Infraestrutura são as dimensões mais frágeis do clima escolar, enquanto as melhor estabelecidas são Amizade, Relações Interpessoais, Acolhimento e Igualdade e Colaboração Mútua.  

Palavras-Chave: Promoção da Saúde. Promoção da Saúde Escolar. Avaliação em saúde.
METODOLOGIAS DE IDENTIFICAÇÃO DE PADRÕES ALIMENTARES A POSTERIORI EM ADULTOS: REVISÃO INTEGRATIVA
Authors: Maria Monteiro Sampaio Rafaella , Bernardo Marinho Leite Nathália , José Maia Pinto Francisco , Pinheiro Machado Arruda Soraia
Published: November 2022

Introdução: A análise das tendências de indicadores globais de saúde mostra o crescimento das prevalências das doenças crônicas não transmissíveis. O padrão alimentar inadequado tem sido associado à ocorrência desses eventos. Ele pode ser definido como um conjunto de alimentos frequentemente consumidos por indivíduos e populações. Na definição a posteriori, parte-se de dados empíricos de alimentos que são agregados com base em análise estatística. Os métodos usados para o cálculo dos padrões alimentares são a análise de agrupamento e a análise de componentes principais (ACP) e a regressão de postos reduzidos (RRR). Objetivo: Realizar um levantamento bibliográfico sobre a identificação de padrões alimentares em adultos saudáveis de abordagem a posteriori. Metodologia: Os artigos foram selecionados por meio de busca em 4 bases de dados, sendo resgatadas 328 publicações. Resultados: Apenas 9 artigos identificaram padrões alimentares por meio de abordagem a posteriori em adultos, sendo 7 do tipo transversal e 2 longitudinal. Conclusão: Ainda são poucos os estudos que identificaram os padrões alimentares em adultos sem patologias associadas utilizando metodologias de abordagem a posteriori, o que representa um grande e importante campo de pesquisa na epidemiologia nutricional a ser explorado para melhor entender o hábito alimentar das diferentes populações no mundo e suas relações com demais fatores.
BRASIL ENTRE O PASSADO E O FUTURO: O QUE TEMOS E O QUE QUEREMOS – MÉTODO DIALÓGICO
Authors: Antônio da Silva Renan , Demo Pedro , Minayo Maria Cecília de Souza , Alves Felipe Freitas de Araújo
Published: November 2022

Este artigo objetiva discutir o que sentimos falta com relação às mudanças no sistema educacional brasileiro (via método dialógico), levando em conta os dados existentes nos últimos governos (Bolsonaro, Dilma e Lula), especificamente sobre a Educação Básica e Superior. Metodologicamente, é um ensaio teórico (pesquisa bibliográfica e documental) com abordagem de análise crítica. A justificativa para esse estudo são as políticas promovidas pelo governo atual que provocam, em nível nacional e internacional, um amplo debate na mídia e nas comunidades científicas. Além de uma possibilidade de refletir sobre o contexto da pandemia e as inseguranças geradas pela ausência de ações governamentais. O levantamento identifica que não há um sistema nacional que coordene as responsabilidades pela educação brasileira. Além disso, há extrema confusão no atual governo, falta investimento público, disputa de um projeto político-ideológico, entre outros fatores que impossibilitam a gestão da educação no país de forma democrática.
The Anti-MRSA Activity of Phenylthiazoles: A Comprehensive Review
Authors: Kassab Asmaa E. , Shahin Inas G. , Mohamed Khaled O. , Taher Azza T. , Mayhoub Abdelrahman S.
Published: November 2022

Antimicrobial resistance is an aggravating global issue therefore it has been under extensive research
in an attempt to reduce the number of antibiotics that are constantly reported as obsolete jeopardizing the lives
of millions worldwide. Thiazoles possess a reputation as one of the most diverse biologically active nuclei, and
phenylthiazoles are no less exceptional with an assorted array of biological activities such as anthelmintic, insecticidal, antimicrobial, antibacterial, and antifungal activity [1]. Recently phenyl thiazoles came under the
spotlight as a scaffold having strong potential as an anti-MRSA lead compound. It is a prominent pharmacophore in designing and synthesizing new compounds with antibacterial activity against multidrug-resistant bacteria such as MRSA, which is categorized as a serious threat pathogen, that exhibited concomitant resistance to
most of the first-line antibiotics. MRSA has been associated with soft tissue and skin infections resulting in
high death rates, rapid dissemination, and loss of millions of dollars of additional health care costs [2]. In this
brief review, we have focused on the advances of phenylthiazole derivatives as potential anti-MRSA from 2014
to 2021. The review encompasses the effect on biological activity due to combining this molecule with various
synthetic pharmacophores. The physicochemical aspects were correlated with the pharmacokinetic properties
of the reviewed compounds to reach a structure-activity relationship profile. A summary of antibacterial activity
of phenylthiazole derivatives against MRSA was added in a tabular form (Table 1). Lead optimization of phenyl thiazole derivatives has additionally been outlined where the lipophilicity of the compounds was balanced
with the metabolic stability and oral solubility to aid the researchers in medicinal chemistry, design, and synthesizing effective anti-MRSA phenylthiazoles in the future.
An Expeditious Synthesis of Ethyl-2-(4-(arylmethylene)-5-oxo-4,5-dihydroisoxazol-3- yl)acetate Derivatives
Authors: Delfani Ali Moradi , Kiyani Hamzeh , Zamani Mehdi
Published: November 2022

In this contribution, an operationally simple and efficient synthetic procedure for synthesizing derivatives of 4-(arylmethylene)-5-oxo-4,5-dihydroisoxazol-3-yl)acetate has been developed. This interesting synthetic protocol involves the one-pot cyclocondensation of diethyl 3-oxopentanedioate, aryl or heteroaryl aldehydes, and hydroxylamine hydrochloride catalyzed in an aqueous medium using an azolium salt as a robust organo-catalyst. In this work, for the first time, 1,3-dibenzyl-1H-benzo[d]imidazol-3-ium chloride was used as the catalyst for the synthesis of ethyl-2-(4-(arylmethylene)-5-oxo-4,5-dihydroisoxazol-3-yl)acetate derivatives from the commercially available starting materials. Notably, no by-products were observed during the multicomponent reaction. Optimization studies revealed that 5 mol% of 1,3-dibenzyl-1H-benzo[d]imidazol-3-ium chloride is sufficient to perform the experiment. Furthermore, examining the results of the temperature conditions showed that 70 ºC is the best temperature to carry out the reaction. In an optimization study, H2O was the most effective solvent to perform the three-component cyclization reaction. In this method, using H2O as the environmentally benign and inexpensive reaction medium, so from the point of view of the reaction medium, it can be said that this three-component heterocyclization obeys the principles of green chemistry. This procedure has several advantages, such as good to excellent yields, reasonable reaction times, isolation of heterocyclic products without column chromatography or other chromatographic methods, atom-economy, step-economy, and clean reaction profiles.
Comprehensive Metabolism Study of Tangeretin in Rat Plasma, Urine and Faeces
Using Ultra-High Performance Liquid Chromatography-Q Exactive Hybrid Quadrupole-
Orbitrap High-Resolution Accurate Mass Spectrometry
Authors: Yu Xiaojun , Cong Zhufeng , Wang Changlin , Wang Shengguang , Yan Zhi , Wang Bin , Liu Xiaonan , Li Zhen , Gao Peng , Kang Huaixing
Published: November 2022

Background:

Tangeretin, present in citrus fruits, is a polymethoxy flavone with extensive pharmacological
effects. It has been widely used in the clinic, but there were no detailed studies on the in vivo metabolism of tangeretin.

Objective:

This study aimed to establish a rapid and effective strategy to identify the metabolites of tangeretin and
evaluate the biotransformation pathways of tangeretin in rats.

Methods:

The ultra-high performance liquid chromatography (UHPLC) equipped with a Q-Exactive Orbitrap mass
spectrometer was used to identify the metabolites of tangeretin in plasma, urine and faeces of rats after intragastric
administration. Based on high-resolution extracted ion chromatograms (HREICs) and parallel reaction monitoring
mode (PRM), metabolites of tangeretin were identified by comparing the accurate mass, chromatographic retention
times, diagnostic product ions (DPIs) and neutral loss fragments (NLFs) with those of tangeretin reference standard.
Isomers were distinguished by ClogP values.

Results:

An efficient and integrated strategy was established for the comprehensive screening and characterizing of
tangeretin metabolites through Rapid Profiling. Based on this strategy, a total of 52 metabolites were detected and
identified, among which 25 metabolites were found in rat plasma, while 48 and 16 metabolites were characterized
from rat urine and faeces, respectively. These metabolites were produced by demethylation, demethoxylation, hydroxylation,
methoxylation, glucuronidation, glycosylation, sulfation, and their composite reactions. Interestingly,
tangeretin is easy to lose methyl in vivo and becomes an intermediate product, and then other phase I and phase II
reactions occur. Moreover, the characteristic fragmentation pathways of tangeretin were summarized for the subsequent
metabolite identification.

Conclusion:

The analytical method based on UHPLC-Q-Exactive mass spectrometer has the ability to quickly clarify
unknown metabolism. And the the comprehensive metabolism study of tangeretin provided an overall metabolic
profile, which will be of great scientific basis for further studies on tangeretin in determining its pharmacokinetics,
the bioactivity of the metabolites, and clinical applications.
Severe Thromboses in Neonates
Authors: Saxonhouse Matthew A. , Hinson Ashley
Published: November 2022

Severe thrombosis in the neonate presents a diagnostic challenge to the clinician as the benefits and risks for treatment must be weighed with every medical decision. Aortic thromboses, large right atrial thromboses, and septic thrombophlebitis present unique clinical challenges that must be managed in the appropriate clinical setting with appropriate subspecialty support. Unfortu-nately, there is limited data on what the ideal therapy should be for these specific types of cases. In this review, we will discuss these types of severe thromboses that may occur in neonates and poten-tial therapies that may offer benefits.
Sertraline: Theoretical Studies and a New Potentiometric PVC Membrane
Sensor for its Determination
Authors: Saber Amr L. , Tuzun Burak , Alessa Hussain , Althakafy Jalal T.
Published: November 2022

Background:

Sertraline (ST) hydrochloride is an anti-depressant of the selective serotonin reuptake inhibitor (SSRI) class. Potentiometric sensors are an appealing route for detecting drugs due to some advantages in terms of sensitivity, feasibility, selectivity, fast response, tolerance to turbidity and colour of solutions, and cost-effectiveness.

Methods:

A mixture of polyvinyl chloride powder (PVC) with o-nitrophenyl octyl ether and the ion association complex was dissolved in tetrahydrofuran (THF) to prepare the membrane for the proposed sensor. The sensor was calibrated and then electrochemically used for detecting ST in pharmaceutical samples.

Results:

The near Nernstian response was observed for a concentration of 1.0 x 10-8 – 1.0 x 10-2 mol L-1 with 58.62 mV as a slope per concentration decade. This direct potentiometric measurement resulted in average recoveries of 96.0 ± 0.2%. Moreover, good selectivity for sertraline with respect to many inorganic and organic cations was observed.

Conclusion:

The proposed sensor was simple to use and produced accurate and precise results. The molecule's chemical and biological activities were revealed using theoretical calculations. Regarding the chemical activities, calculations were made on the 3-21g and 6-31g while the SDD bases were set at B3LYP, HF, and the M062X level. Molecular docking calculations were designed against cancer proteins in order to have details regarding the molecule's biological activity.
Gastric Cancer Derived Mesenchymal Stem Cells Promote the Migration
of Gastric Cancer Cells Through miR-374a-5p
Authors: Ji Runbi , Lin Jiang , Gu Hongbing , Ma Jichun , Fu Min , Zhang Xu
Published: November 2022

Introduction:

Resident mesenchymal stem cells (MSCs) in the tumor microenvironment play an important role in tumor progression. Up to now, the mechanism of resident MSCs promoting gastric cancer cell migration remains unclear.

Methods:

We tested the migration ability of gastric cancer cells by transwell assays in this study. The inflammatory factors secreted by MSCs were detected by Luminex and ELISA. The activation of NF-κB signaling was detected by western blot. The exosomes derived from MSCs were isolated and identified by transmission electron microscope, nano-sight and western blot. The expression of miR-374a-5p was confirmed by qRT-PCR and its downstream target HAPLN1 by luciferase reporter assay. The expression of adhesion molecules of gastric cancer cells was detected by flow cytometry.

Results:

MiR-374a-5p could regulate the expression of inflammatory factors by activating NF-κB signaling.
The increase of MCP-1 and the decrease of IFN-γ promoted the migration of gastric cancer cells. The
miR-374a-5p in MSCs could be encapsulated and delivered to gastric cancer cells by exosomes derived
from MSCs. Exogenous miR-374a-5p up-regulated the expression of adhesion molecules in gastric cancer
cells by targeting HAPLN1. And miR-374a-5p-enriched exosomes also promoted the migration of gastric
cancer cells.

Conclusion:

MiR-374a-5p promoted gastric cancer metastasis, and resident MSCs in the gastric cancer microenvironment played a major role in the regulation of gastric cancer metastasis. The study will provide new ideas and potential targets for the prevention and treatment of gastric cancer metastasis.
Rural Youth Employability Trends and the COVID-19 Pandemic
Authors: Grinevica Liva , Rivza Baiba , Rivza Peteris
Published: November 2022

Background:

The COVID-19 pandemic seriously impacts youth employability, especially in rural regions. In rural areas, the lack of system and availability of education, vocational education and training can have a negative impact on a young person's ability to obtain an education and continue to succeed in the labour market. These circumstances can hinder a young person's transition to the labour market.

Aims and Objectives:

The paper presents a brief analysis of rural youth employment trends, the consequences of the COVID-19 pandemic for the labour market in Latvia, and an analysis of the youth employability using dynamic series analysis.

Methods:

The research methodology implemented for the present research study is based on the theoretical concepts and statistical data regarding the rural youth employment trends and the impact of the COVID-19 pandemic.

Results:

Based on the results of the research study, it can be concluded that COVID-19 has contributed to job losses by forcing young people from rural areas to move to a city with better access to employment. The authors have concluded that educated women tend to start their own businesses after graduation, which is positive, especially if it is based in rural areas.

Conclusion:

Based on the authors' calculations, the forecast of employees in the age group from 25 to 34 in Latvia in 2022 is 171.9 thousand, in 2023, it is 156.5 thousand, and in 2024 it is 138.9 thousand. It could be concluded that the projected number of employees in the 25-34 age group will decrease significantly.
Exploring Physical and Non-physical Infrastructure of Bus Rapid Transit and its Connectivity to Intermodal Transport Modes in Semarang
Authors: Rakhmatulloh Anita Ratnasari
Published: November 2022

Background:

The modern service of public transport system in a developing country is still in the stage of embryo compared to other big cities in the world. Providing reliable and affordable intermodal transportation is a major challenge in Indonesia, particularly in a growing city such as Semarang. The higher volume of traffics in this city leads to critical congestion due to the imbalance between transport infrastructures, mobility management, and travel behaviour. The concept of Bus Rapid Transit was adopted as a transport policy, and it was introduced in Semarang reduce congestion and car dependency as well as to enhance integration of intermodal transport modes. However, there is still a lack of transport infrastructure to support connectivity and integration between Bus Rapid Transit (BRT) and intermodal transportation modes that might influence the willingness to use public transport.

Objective:

The study aims to explore the physical and non-physical facilities to connect between Bus Rapid Transit (BRT) with intermodal transportation modes in Semarang.

Methods:

The research using qualitative method combined with four approaches such as quantitative, phenomenological, literature, and study-case based approaches.

Results:

The research reveals that the intermodal transportation system which employs integration of modes (airport, port, and railway station) improves the efficiency of travel and bus transit experience. Both physical and non-physical public transport amenities are still underrated and there is a need for improvements to make it more reliable, attractive, and easier for transport users (students and non-students). Moreover, the number of transport users dropped dramatically during the COVID-19 pandemic. Furthermore, the lack of public transport infrastructure and amenities results in an inconvenient experience of travel and a decline in the number of bus ridership.

Conclusion:

The local government should creatively improve the physical and non-physical facilities to support Bus Rapid Transit (BRT) services and its connectivity to intermodal transport modes in intercity passengers’ terminals (airport, port and railway stations) in terms of sidewalks, amenities, payment methods, and information system.
Psychometric Evaluation of the Short form of Interpersonal Influences Scale for Stretching Exercise among the Office Employees Based on the of Health Promotion Model in an Iranian Version
Authors: Delshad Mohammad Hossien , Tavafian Sedigheh Sadat , Kazemnejad Anoshirvan , Pourhaji Fatemeh
Published: November 2022

Background:

Interpersonal influences are critical key points for stretching exercise predicting. In Iran, there's no measure to observe interpersonal Influences amongst workplace office employees.

Objective:

The purpose of this study was to investigate the short form psychometrics of Interpersonal Influences scale for Stretching Exercise predicting among based on Health Promotion Model (HPM) With Added Constructs.

Methods:

By multistage cluster sampling method, this cross-sectional study was done among 385 office employees were selected from the Health networks at Shahid Beheshti University of Medical Sciences of Iran (SBUMS).

Results:

The EFA is shown via the principle component approach one factor with 77% cumulative variance and Kaiser-Mayer-Olkin (KMO) became 90.7%; p -value< 0.001. This was the good fit index in Confirmatory Factor Analysis (CFA). Also With the help of Construct validity, factor was explanted. Within the CFA area, Root Mean Square Error of Approximation (REMSEA) result display= 0.059, Goodness of Fit Index (GFI) = 0.966, Adjusted Goodness of Fit Index (AGFI) = 0.985 confirmed with Cronbach’s alpha (α = 0.834%) and [ (ICC) =0.79 95% Confidence ICCnterval (CI) (0.58, 0.84)].

Conclusion:

This study generated a Persian-language version of the Interpersonal Influences scale among the office employees Based on the of HPM.
Sprint Performance Determinants in High-level Young Swimmers
Authors: Matos Carolina L. , Conceição Ana T. , Louro Hugo G. , Neiva Henrique P. , Sobreiro Pedro N. , Viana Bárbara L. , Marinho Daniel A.
Published: November 2022

Background:

Identifying and evaluating the variables that influence performance are essential for obtaining excellence in sport.

Objective:

This study aimed to identify which parameters have the most influence on the 50 meters freestyle time in young competitive swimmers.

Methods:

One hundred and eighty-four high-level swimmers (males, n=92: 14.60±0.56 years; females, n=92: 13.53 ± 0.54 years) with 468±66 FINA points in the 50 meters freestyle short course participated in this study. Age, height, body mass, wingspan, stroke rate, stroke length, stroke index, turning time (5 m + 10 m), horizontal jumping, and medicine ball throwing were assessed. The swimming performance was assessed in a 50 meters freestyle time trial at maximum speed in a 25 meters swimming pool. Multiple regression was performed to assess the relationship between one dependent variable (50 meters freestyle time) and independent variables.

Results:

The results showed significant differences between both the genders. In male swimmers, only the turning time and the horizontal jump were significant (r2=0.8819; p<0.001), while females, besides the same variables, presented significant results in terms of height, body mass, stroke length, and stroke index (r2=0.9013; p<0.01).

Conclusion:

In conclusion, in young male swimmers, the turning time and the horizontal jump contributed significantly to the 50 meters freestyle swimming performance, and in young female swimmers, the main contributors were the turning time, horizontal jump, height, body mass, stroke length, and stroke index.
The General Solution of the Phase Difference Positioning Equation
Authors: Yu Tao
Published: November 2022

For passive positioning technology, not only the signal transmitting time
of the target is not known at all, but also the initial phase of the signal is not known.
Therefore, the phase comparison method cannot be used. But if we just use geometry,
starting from the basic definition of phase shift detection of distance, it is explained
in mathematical form that, because phase shift measurement has the fuzziness of
period, the number of wavelengths contained in the observed quantity itself is an
unknown variable to be determined, so the positioning equation based on phase shift
measurement is unsolvable if we only use existing analytical methods. If the unknown
quantity representing the period ambiguity is regarded as an undetermined quantity,
the solution of the phase difference localization equation can still be obtained
formally. As a mathematical basis, this chapter gives a linear solution method of
passive positioning equation based on path difference measurement in two
dimensional plane. In the passive positioning problem based on path difference
measurement in two-dimensional plane, it is generally necessary to use at least 3 or
more measuring stations to collect data to get the path difference between the radiation
source and each measuring station. The existing method is to make use of these
distance differences to form a set of nonlinear hyperbolic equations about the position
of the radiation source, and the coordinate position of the radiation source can be
obtained by solving the hyperbolic equations. The author's existing research results
show that for the plane multi-station positioning problem, the linear equations can be
obtained if the auxiliary equations are constructed by using the existing plane
geometric relations on the basis of the path difference measurement.
Unambiguous Phase Difference Measurement of Positioning Parameters
Authors: Yu Tao
Published: November 2022

Through a simple angle substitution, we can obtain the corresponding
relationship between frequency shift and phase difference. Based on this relationship,
the Doppler shift can be obtained by simple phase difference measurement. However,
the reason why the function relation between phase shift and frequency shift can
produce the expansion efficiency is also due to the relationship, that is obtained by
the first order change of distance, between the rate of change of phase shift and the
Doppler frequency shift. It's just a simple mathematical generalization of what's
already known. Further, based on the two basic modes of angle permutation and first order change, various relations between phase shift and frequency shift, as well as
their first order change, can be determined. This mathematical description extends to
physical applications, enabling many motion parameters and observations that would
otherwise be difficult to detect to be obtained by simple phase shift/difference
detection.
Unambiguous Phase Difference Direction Finding Based on Short Baseline Array
Authors: Yu Tao
Published: November 2022

In this chapter, the fuzzy-free phase difference direction finding method
based on a short baseline array is introduced and three different methods are
presented. Firstly, the virtual short baseline direction finding method based on one dimensional double-base asymmetrical array is studied deeply, which is constructed
by subtraction of the ratio of different sides between two adjacent baselines. The
author's findings show that, although the difference between the lengths of two
adjacent baselines is less than half a wavelength, the difference of the integers of
wavelengths will not be zero in the direction of partial arrival angles but will jump.
In this regard, the correction can be realized by the determination of the sine value of
the arrival angle by adopting a method like the fuzzy-free detection analysis of the
phase difference rate. The second approach is the orthogonal phase difference
direction finding method based on equivalent simulation. It is found in the simulation
that the curve shape of the differential function of path difference per unit wavelength
obtained after phase jump correction is very similar to that of the cosine function. If
the maximum value of the function is used for normalization processing and simple
square root processing, then the function obtained is basically equivalent to the cosine
function. At this time, it can be proved in principle that the results given are equivalent
to the Doppler direction finding technique. Then, using the orthogonal array, the
maximum value of the function which cannot be known in the one-dimensional array
is eliminated by means of the orthogonal ratio, so the real-time direction finding based
on phase difference measurement without phase ambiguity is realized. The third
approach is the airborne direction finding method based on Doppler-phase
measurement. The study shows that the airborne single-baseline interferometer can
achieve high precision direction finding without phase ambiguity after integrating
Doppler measurement information. The main method is to directly obtain the
wavelength integer solution of the radial distance by comprehensively utilizing the
velocity vector equation, Doppler frequency shift and its rate of change. Thus, the
integral value of the wavelength contained in the path difference between two
adjacent array elements can be given. By means of the phase difference measurement,
the value less than the wavelength integer in the path difference can be determined.
This chapter also explores the effect of phase difference measurement errors on the
difference of wavelength integers. The expression of the wavelength number
difference based on the phase difference measurement can also be approximated by
the unambiguous phase difference direction finding method based on the virtual short
baseline. The root mean square measurement error of the wavelength number difference is derived. Through analysis, it is revealed that the wavelength number
difference has little effect on the accuracy of a single baseline phase difference
direction finding.
Algorithm For Intelligent Systems
Authors: Dhoke Pratik , Saraf Pranay , Bhalandhare Pawan , Pandey Yogadhar , Deshmukh H.R. , Agrawal Rahul
Published: November 2022

In the 21st-century, machines are becoming more and more intelligent. Terms like artificial intelligence, automation, robotics, etc., are becoming the new normal in today's tech-savvy world. All of this is made possible because of complex programs (algorithms) which are able to perform such difficult tasks.

Intelligent systems are self-taught machines intended for a particular task. Intelligence is the ability to learn and use new information and skills. As the person learns from past data, the system can be programmed using various algorithms to make it intelligent.

In this chapter, we will be discussing some of the algorithms in brief, like- Reinforcement learning, Game theory, Machine Learning, Decision Tree, Artificial Neural Networks, Swarm Intelligence, and Natural Language Processing and its applications.
Deadly Disinformation
Authors: Moskalenko Sophia , Romanova Ekaterina
Published: November 2022

Viral online disinformation is misleading content that is generated to manipulate public opinion and to circulate rapidly in the digital space. Although viral disinformation has become an instrument for radicalization, the specific psychological mechanisms by which disinformation can be weaponized––wielded as mobilizing and radicalizing political tools––are not yet well-understood.
In this paper, we establish the potential of concerted disinformation efforts to impact mass radicalization and political violence, first through historical precedents of deadly disinformation campaigns, then in modern-day examples from the USA and Russia. Comparing and contrasting political effects of two recent disinformation campaigns, QAnon’s #SaveTheChildren campaign in the USA, and anti-LGBTQ disinformation campaign in Russia, this paper highlights the significance of LGBTQ contagion threat—a notion that people can be “turned” into LGBTQ through deliberate outside influence. The psychological and political consequences of such messaging, its main target audience, and vulnerability factors rendering individuals especially susceptible to its radicalizing effects are discussed.
Assessing the Implications for Children in Violent Extremist Families
Authors: Cook Joana
Published: November 2022

On September 8, 2022, the Canadian Association for Security and Intelligence Studies (CASIS) Vancouver hosted the Defence and Security Advisory Network (DSAN) workshop in which Dr. Joana Cook, Senior Project Manager at the International Centre for Counter-Terrorism (ICCT) and Editor-in-Chief of the ICCT Journal, presented on Assessing the Implications for Children in Violent Extremist Families. The presentation was followed by a moderated question-and-answer period in which the audience was able to deepen their understanding of the topic. The discussion centered around understanding the context of children who are affiliated with violent extremist (VE) groups so that practitioners can better support them and address their specific needs.
Samen vooruit
Authors: Willems Stefan
Published: November 2022

Wie denkt aan pathologie, denkt aan microscopie. Dankzij de microscoop ging een wereld voor ons open. Dit leidde tot inzicht in het ontstaan en het beter classificeren van ziekten, en leerde ons op abstracter niveau ook een belangrijk principe: dat samenwerking loont. Pathologie is een verbindend specialisme zowel binnen de patiëntenzorg als het onderzoek, alsook daartussen. Aan deze rol dankt de pathologie haar positie, haar kracht, maar ook haar identiteit: alleen door deze verbinding kan de pathologie bestaan. We hebben niet alleen geleerd dat samenwerken noodzakelijk is, het brengt ons ook verder. De grootste vooruitgang binnen ons vak zoals op het gebied van de digitale en moleculaire pathologie komt juist door kruisbestuiving met andere domeinen. Samenwerken Het vereist moed om muren tussen domeinen te laten zakken, over eigen grenzen heen te reiken en ook toestaan dat anderen dat bij jou doen. Dat geldt voor zowel samenwerkingen binnen verschillende diagnostische disciplines, alsook netwerksamenwerkingen tussen verschillende ziekenhuizen. Hier liggen niet alleen kansen. Het is ook noodzakelijk om de academische pathologie levendig te houden, de best mogelijke diagnostiek te leveren en de zorg betaalbaar te houden. Onderwijs en opleiding spelen een cruciale rol in deze transitie. Niet alleen zijn zij essentieel voor de verdere integratie van kennis op het gebied van IT, digitalisering en automatisering binnen de opleiding tot arts en patholoog. Maar nog belangrijker: ze leidt op tot een patholoog die leert kijken vanuit de ander, met een breder, integraler perspectief, gestoeld op een nieuwe vorm van leiderschap. Minder ik, meer wij. Alleen samen komen we vooruit.
Concentración sérica de la hormona anti-Mülleriana y su relación con la reserva ovárica en vacas Brahman donantes de ovocitos
Authors: Riveros-Pinilla Diego Armando , Bespalhok-Jacometo Carolina , Corrales-Álvarez Juan David , Olaya-Oyuela Julio Cesar , Chacón-Jaramillo Liliana
Published: November 2022

Objetive. To evaluate the relationship of AMH blood concentration with ovarian follicular count and in vitro embryo production in female Brahman cattle. Material and methods. To standardize the AMH quantification for Brahman donors, experiment 1 was performed, blood samples were taken from 10 heat synchronized Brahman females, in three different days of the estrous cycle, with more than 90 days postpartum and with normal reproductive evaluation. Serum concentration of AMH was determined with a commercial immunoenzymatic kit. After the technique was standardized, blood samples were taken from 100 non-synchronized Brahman oocyte donors, an ovum pick-up session was performed for in vitro embryo production and the number of follicles greater than 2 mm in the two ovaries was registered. Results. There were no differences in AMH concentration between the evaluated days of estrous cycle and a correlation of 0.82 (p<0.001) was found between antral follicle population (AFP) and AMH concentration. Serum AMH concentration ranged from 0.02 to 2.69 ng/ml in Brahman oocyte donors. Also, a correlation of 0.73 (p<0.001)  between AMH and AFP and 0.54 between the AMH and the percentage of blastocysts were found in donors. Conclusions. The AMH can be used as a satisfactory endocrine marker of ovarian reserve prediction for in vitro embryo production in Brahman cattle.
Impacts of GlobalConsent, a Web-Based Social Norms Edutainment Program, on Sexually Violent Behavior and Bystander Behavior Among University Men in Vietnam: Randomized Controlled Trial
Authors: Yount Kathryn M , Cheong Yuk Fai , Bergenfeld Irina , Trang Quach Thu , Sales Jessica M , Li Yiman , Minh Tran Hung
Published: November 2022

Background

Sexual violence against women is prevalent worldwide. Prevention programs that treat men as allies and integrate a bystander framework are emerging in lower income settings, but evidence of their effectiveness is conflicting.

Objective

This study aimed to test the impact of GlobalConsent on sexually violent behavior and prosocial bystander behavior among university men in Vietnam.

Methods

We used a double-blind, parallel intervention versus control group design with 1:1 randomization at 2 universities. A total of 793 consenting heterosexual or bisexual men aged 18-24 years who matriculated in September 2019 were enrolled and assigned randomly to GlobalConsent or an attention-control adolescent health education (AHEAD) program. GlobalConsent is an adapted, theory-based, 6-module web-based intervention with diverse behavior change techniques and a locally produced serial drama. AHEAD is a customized, 6-module attention-control program on adolescent health. Both the programs were delivered to computers and smartphones over 12 weeks. Self-reported sexually violent behaviors toward women in the prior 6 months and prosocial bystander behaviors in the prior year were measured at 0, 6, and 12 months.

Results

More than 92.7% (735/793) of men in both study arms completed at least 1 program module, and >90.2% (715/793) of men completed all 6 modules. At baseline, a notable percentage of men reported any sexually violent behavior (GlobalConsent: 123/396, 31.1%; AHEAD: 103/397, 25.9%) in the prior 6 months. Among men receiving GlobalConsent, the odds of reporting a high level (at least 2 acts) of sexually violent behavior at the endline were 1.3 times the odds at baseline. Among men receiving AHEAD, the corresponding odds ratio was higher at 2.7. The odds of reporting any bystander behavior at endline were 0.7 times the odds at baseline for GlobalConsent, and the corresponding odds ratio for AHEAD was lower at 0.5.

Conclusions

Compared with a health attention-control condition, GlobalConsent has sustained favorable impacts on sexually violent behavior and prosocial bystander behavior among matriculating university men in Vietnam, who would otherwise face increasing risks of sexually violent behavior. GlobalConsent shows promise for national scale-up and regional adaptations.

Trial Registration

ClinicalTrials.gov NCT04147455; https://clinicaltrials.gov/ct2/show/NCT04147455

International Registered Report Identifier (IRRID)

RR2-10.1186/s12889-020-09454-2