bluuebunny/crossref_metadata_2025 huggingface dataset:
Caring jacket: health monitoring jacket integrated with the internet of things for COVID-19 patients
Authors: Maghfiroh Hari , Kusumastuti Daru , Sari Rebbeka Siswandina , Al-Choiri Muhammad Hammam , Afif Maulana , Baballe Muhammad Ahmad
Published: May 2024

One of the policies that have been made by the World Health Organization (WHO) and the Indonesian government during this COVID-19 pandemic, is to use an oximeter for self-isolation patients. The oximeter is used to monitor the patient if happy hypoxia which is a silent killer, happens to the patient. To maintain body endurance, exercise is needed by COVID-19 patients, but doing too much exercise can also cause decreased immunity. That’s why fatigue level and exercise intensity need to be monitored. When exercising, social distancing protocol should be also reminded because can lower COVID-19 spreading up to 13.6%. To solve this issue, the Caring Jacket is proposed which is a health monitoring jacket integrated with an IoT system. This jacket is equipped with some sensors and the global positioning system (GPS) for tracking. The data from the test showed the temperature reading accuracy is up to 99.38%, the oxygen rate up to 97.31%, the beats per minute (BPM) sensor up to 97.82%, and the precision of all sensors is 97.00% compared with a calibrated device.
National archival platform system design using the microservice-based service computing system engineering framework
Authors: Ramdhani Taufik Iqbal , Faiza Ninon Nurul
Published: May 2024

Archives play a vital function concerning the dynamics of people and nations as an instrument to treasure information in diverse domains of politics, society, economics, culture, science, and technology. The acceleration of digital transformation triggers the implementation of a smart government that supports better public services. The smart government encourages a national archival system to facilitate archive producers and users. The four electronic-based government system (SPBE) factors in the archival sector and open archival information system (OAIS) as a data preservation standard are the benchmarks in developing this study's national archival platform system. An improved service computing system engineering (SCSE) framework adapted to the microservice architecture is used to aid the design of the national archival platform system. The proposed design met the four-factor service design validation of coupling, cohesion, complexity, and reusability. Also, the prototype suggests what resources are needed to put the design into action by passing the performance test of availability measurement.
An LSTM-based prediction model for gradient-descending optimization in virtual learning environments
Authors: Ismanto Edi , Effendi Noverta
Published: May 2024

A virtual learning environment (VLE) is an online learning platform that allows many students, even millions, to study according to their interests without being limited by space and time. Online learning environments have many benefits, but they also have some drawbacks, such as high dropout rates, low engagement, and students' self-regulated behavior. Evaluating and analyzing the students' data generated from online learning platforms can help instructors to understand and monitor students learning progress. In this study, we suggest a predictive model for assessing student success in online learning. We investigate the effect of hyperparameters on the prediction of student learning outcomes in VLEs by the long short-term memory (LSTM) model. A hyperparameter is a parameter that has an impact on prediction results. Two optimization algorithms, adaptive moment estimation (Adam) and Nesterov-accelerated adaptive moment estimation (Nadam), were used to modify the LSTM model's hyperparameters. Based on the findings of research done on the optimization of the LSTM model using the Adam and Nadam algorithm. The average accuracy of the LSTM model using Nadam optimization is 89%, with a maximum accuracy of 93%. The LSTM model with Nadam optimisation performs better than the model with Adam optimisation when predicting students in online learning.
Constraint satisfaction algorithms: edition of timetables in the license-master-doctorate system
Authors: Comlan Maurice , Allohoumbo Corentin
Published: May 2024

In this paper, we studied some algorithms for solving constraint satisfaction problem (CSP) and then applied them to solve the problem of generating schedules in a university setting. In other words, we studied the genetic algorithm, the simulated annealing, the hill climbing, a hybridization of the genetic algorithm and the simulated annealing as well as a hybridization of the genetic algorithm and the hill climbing. These algorithms have been tested on the problem of scheduling in a university environment. The hybrid uses hill climbing or simulated annealing to improve each individual in the starting population to a certain stopping point. These individuals are then sent to the genetic algorithm. Our results show that the hybridization of the genetic algorithm with a metaheuristic gives better execution time and performs better as the problem size increases compared to the classical genetic algorithm.
Generalization of linear and non-linear support vector machine in multiple fields: a review
Authors: Khan Sundas Naqeeb , Khan Samra Urooj , Aznaoui Hanane , Şahin Canan Batur , Dinler Özlem Batur
Published: May 2024

Support vector machines (SVMs) are a set of related supervised learning methods used for classification and regression. They belong to a family of generalized linear classifiers. In other terms, SVM is a classification and regression prediction tool that uses machine learning theory to maximize predictive accuracy. In this article, the discussion about linear and non-linear SVM classifiers with their functions and parameters is investigated. Due to the equality type of constraints in the formulation, the solution follows from solving a set of linear equations. Besides this, if the under-consideration problem is in the form of a non-linear case, then the problem must convert into linear separable form with the help of kernel trick and solve it according to the methods. Some important algorithms related to sentimental work are also presented in this paper. Generalization of the formulation of linear and non-linear SVMs is also open in this article. In the final section of this paper, the different modified sections of SVM are discussed which are modified by different research for different purposes.
Agile adoption challenges in insurance: a systematic literature and expert review
Authors: MunandA Krishna Yudhakusuma Putra , Raharjo Teguh
Published: May 2024

The drawback of agile is struggled to function in large businesses like banks, insurance companies, and government agencies, which are frequently associated with cumbersome processes. Traditional software development techniques were cumbersome and pay more attention to standardization and industry, this leads to high costs and prolonged costs. The insurance company does not embrace change and agility may find themselves distracted and lose customers to agile competitors who are more relevant and customer-centric. Thus, to investigate the challenges and to recognize the prospect of agile adoption in insurance industry, a systematic literature review (SLR) in this study was organized and validated by expert review from professional with expertise in agile. The project performance domain from project management body of knowledge (PMBOK) was applied to align the challenges and the solution. Academicians and practitioners can acquire the perception and knowledge in having exceeded understanding about the challenge and solution of agile adoption from the results.
Safeguarding data privacy: strategies to counteract internal and external hacking threats
Authors: Jamal Hassan , Algeelani Nasir Ahmed , Al-Sammarraie Najeeb Abbas
Published: May 2024

In the digital age, the protection of data privacy has become increasingly important. Hackers, whether internal or external to an organization, could cause significant damage by stealing sensitive data, causing financial loss, compromising the privacy of individuals, or damaging the organization's reputation. This scientific research aimed to make substantial contributions by emphasizing the importance of addressing both internal and external hacking threats to protect sensitive information. The main theme of their work revolved around building a multi-layered defense system that included technological solutions like firewalls, encryption, and intrusion detection systems. The specific goals of their design and development approach were to establish clear policies and procedures for data handling, access control, and incident response, as well as to enhance data privacy strategies to stay ahead of evolving hacking techniques. The authors also highlighted the significance of employee awareness and training programs, collaboration with cybersecurity experts, and staying up-to-date with regulatory requirements to create a robust data privacy framework.
Fingerprint based smart door lock system using Arduino and smartphone application
Authors: Sutikno Tole , Ubaidillah Moh Ainur Faqih , Arsadiando Watra , Purnama Hendril Satrian
Published: May 2024

In 2023, crime cases in Indonesia will reach 105,133. Cases of theft with aggravation dominate the majority of cases. Everyone is concerned about safety, but doors are typically opened and closed using physical keys. This is vulnerable to being tampered with with fake keys, which can lead to house break-ins and theft. In this research, we propose a fingerprint-based wireless door lock design using Arduino and a smartphone. We offer this solution as a preventive measure to reduce the high rate of theft in homes or other buildings. The devices used are Arduino UNO R3, fingerprint sensor, HC-05 Bluetooth module, buzzer, and door lock solenoid. The results of the fingerprint-based wireless door lock using Arduino and a smartphone can function well, with an average response time of 1.20 seconds. Furthermore, testing the HC-05 Bluetooth when sending signals to a smartphone shows that it can read data accurately with an average response time of 1.54 seconds.
Prognostic Value of Microvascular Resistance Reserve Measured Immediately After PCI in Stable Coronary Artery Disease
Authors: Nishi Takeshi , Murai Tadashi , Waseda Katsuhisa , Hirohata Atsushi , Yong Andy S.C. , Ng Martin K.C. , Amano Tetsuya , Barbato Emanuele , Kakuta Tsunekazu , Fearon William F.
Published: May 2024

BACKGROUND:

Microvascular resistance reserve (MRR) has been proposed as a specific metric to quantify coronary microvascular function. The long-term prognostic value of MRR measured in stable patients immediately after percutaneous coronary intervention (PCI) is unknown. This study sought to determine the prognostic value of MRR measured immediately after PCI in patients with stable coronary artery disease.

METHODS:

This study included 502 patients with stable coronary artery disease who underwent elective PCI and coronary physiological measurements, including pressure and flow estimation using a bolus thermodilution method after PCI. MRR was calculated as coronary flow reserve divided by fractional flow reserve times the ratio of mean aortic pressure at rest to that at maximal hyperemia induced by hyperemic agents. An abnormal MRR was defined as ≤2.5. Major adverse cardiac events (MACEs) were defined as a composite of all-cause mortality, any myocardial infarction, and target-vessel revascularization.

RESULTS:

During a median follow-up of 3.4 years, the cumulative MACE rate was significantly higher in the abnormal MRR group (12.5 versus 8.3 per 100 patient-years; hazard ratio 1.53 [95% CI, 1.10–2.11];
P
<0.001). A higher all-cause mortality rate primarily drove this difference. On multivariable analysis, a higher MRR value was independently associated with lower MACE and lower mortality. When comparing 4 subgroups according to MRR and the index of microcirculatory resistance, patients with both abnormal MRR and index of microcirculatory resistance (≥25) had the highest MACE rate.

CONCLUSIONS:

An abnormal MRR measured immediately after PCI in patients with stable coronary artery disease is an independent predictor of MACE, particularly all-cause mortality.
Contextual and Individual-Personal Predictors of Russians’ Adaptation in Estonia and Kyrgyzstan
Authors: Trifonova Anastasia V. , Lebedeva Nadezhda M.
Published: May 2024

Background. Acculturation strategy choice and success of adaptation to new cultural environment depend both on individual characteristics of participants of intercultural interaction and on characteristics of the context. In this regard, it is important to apply an integrated approach to study the mutual contribution of contextual and individual-personal predictors of acculturation. Objective. The study aims at identifying complex contextual and individual-personal predictors of adaptation of Russians in Estonia and Kyrgyzstan, and revealing relationship between these complex predictors, acculturation strategies, and psychological well-being of Russians in these republics. Study Participants. The sample consisted of 302 Russians in Estonia (Mage = 37.51; SD = 16.55; 52% females) and 300 Russians in Kyrgyzstan (Mage = 35.56; SD = 17.40; 64,8% females). Methods. We used scales from the MIRIPS questionnaire, instruments for measuring identities and intercultural attitudes developed in CSCR of HSE, and local identity scale by O. Droseltis and V.L. Vignoles. Results. The study revealed three complex predictors of adaptation in each country: perceived inclusiveness of context, ethnocultural identity and closeness to host country. These three complex factors in both countries were positively associated with life satisfaction, and in Estonia with self-esteem as well. Perceived inclusiveness of the context and closeness to host country negatively related to separation and positively related to integration, ethno-cultural identity positively related to separation. In Kyrgyzstan we also revealed culture-specific positive links between ethno-cultural identity and integration and between closeness to host society and assimilation. Conclusion. The study of the mutual contribution of personal and contextual characteristics to success in adaptation to new cultural environment contributes to a deeper understanding of acculturation as a complex dynamic process, the components of which are in constant interaction with each other.
University Staff Well-Being and Various Psychological Aspects of their Professional Activity
Authors: Denisova Ekaterina G. , Bovdui Diana A. , Gosteva Anastasia O.
Published: May 2024

Background. Modern rhythm of life determines the need to accelerate the overall personal productivity and forces us to face systematic strain and stress. In this regard, individual resources and subjective well-being are of particular importance as factors that can prevent burnout and social maladjustment. The problem of psychological health in educational staff is especially significant, since they affect the academic process and the well-being of students. Objective. The research aims to study psychological well-being of university staff in connection with their professional motivation, the levels of job satisfaction, and professional burnout. Study Participants. The empirical study involved 140 people aged 20 to 80, university staff, of both sexes and with different social status. Methods. The study was carried out using the Method for diagnosing the subjective well-being of a person (R.M. Shamionov, T.V. Beskova), Motivation Sources Inventory (version of E.V. Sidorenko), Professional maladaptation questionnaire (O.N. Rodina), Job Satisfaction Survey (P. Spektor), Maslach Burnout Inventory (version by N.E. Vodopyanova). Statistical methods included Shapiro — Wilk test, Spearman's rank-order correlation. Statistical analysis was carried out using the JASP 0.16 software. Results. It has been established that an increase in the levels of professional burnout components correlates with a decrease in the levels of psychological well-being, professional motivation and job satisfaction (р < 0.05). It is also shown that the correlations between professional burnout with the components of professional motivation are different in groups with different work experience in education. Conclusions. The results obtained made it possible to identify the most significant factors in professional motivation and job satisfaction that affect psychological well-being and the development of professional burnout among educators.
Turn the Mirror of Your Soul
Authors: Stock Wiebke-Marie
Published: May 2024

Plotinus treats memory not simply as a capacity of the soul, but as an essential part of the process of the soul’s ongoing self-formation. Plotinus argues that memory and forgetting affect the soul, now and in the future. Since memories define who one is and who one is going to be, the soul must learn how it can or should shape memories. I address the topic of memory-shaping in Plotinus not only as an epistemological and metaphysical topic or an ethical problem, but as a “psychological” or “psychotherapeutic” issue.
Jesus and the Samaritan Woman
Authors: Yusuf Obed L. , Chiroma Nathan H.
Published: May 2024

Over the years, youth ministry has witnessed remarkable growth, transforming from a fledgling field into a fully-fledged Christian ministry and a viable profession. This growth gave its academicians the responsibility to conduct research and steer youth ministry in a biblical direction. In line with this great yet noble responsibility, this article explores Jesus’ conversation with the Samaritan woman in John 4 as a basis for developing a biblical model for youth ministry. The model in this article is constructed on a foundation that amalgamates insights gleaned from biblical narratives and developmental psychology. By exploring the story of Jesus and the Samaritan woman, as recorded in John 4:1–42, this article argued that the biblical model for youth ministry is to introduce young people to Jesus so they can believe in him as the Messiah and be incubated in his word to help them develop personal conviction, which will inevitably transform and lead them to exhibit love-rooted, grace-enabled actions.
Microstructure Evolution and Creep Properties of AZ61 Magnesium Matrix Composites Reinforced with Bimodal-Sized SiC Particles
Authors: Li Ming , Zhao Zu-De , Xing Zhi-Hui , Yao Meng-Ling , Zhao Gao-Zhan , Du Chuan-Hang , Xiang Lin , Wang Hong-Xia
Published: May 2024

In the scope of this exploration, AZ61 magnesium matrix composites fortified with bimodal size SiC particles were synthesized using ultrasonic-assisted mixing in the semi-solid state, which exhibited optimal grain refinement and exceptional creep resistance. We examined the impact of
bimodal SiC particles on the microscopic structure and creep deformation of the resulting composites. Our findings indicated that incorporating bimodal SiC particles resulted in the refinement of the matrix grains and alteration of the morphology of the Mg17Al12 phase.
Furthermore, the micron-sized SiC particles exhibited a typical necklace-like particle distribution around the grain boundaries of the bimodal SiC particle/AZ61 composites, while the nano-sized SiC particles were mainly located around the micron-sized particles. As the volumetric percentage
of micron SiC particles increased, the quantity of nano-sized particle clusters diminished noticeably. Creep analysis at 200 °C and 50 MPa revealed that the creep life of M−6+N−1 composite was increased by 111.9% compared to the AZ61 alloy. Additionally, the M−6+N−1
combination exhibited a significantly lower steady-state creep rate compared to the matrix alloy, with a reduction of approximately 11 times. These results indicate that the bimodal SiC particle/AZ61 composites have superior creep resistance, which is a consequence of the grain refinement
and grain boundary pinning effects of SiC particles.
One Pot Synthesis of Phosphomolybdenate Based Hybrids for Efficient Oxidative Desulfurization
Authors: Su Yizhen , Sheng Jiangfeng , Tang Aiqing , Zhu Linhua
Published: May 2024

With increasing stringent standard of sulfur content in fuels, there is a growing need for high-efficiency deep desulfurization to meet ecological and environmental demands. Herein, a series of heteropolyacid catalysts with phosphomolybdic acid base melamine (MHPMo-n) were synthesized
by one-pot method and applied to oxidative desulfurization. Further, the optimum conditions for desulfurizations could be explored, which the desulfurization rate of the catalyst could reach 100% within 60 min under the conditions of m(catalyst)= 0.01 g, T = 40 °C, O/S = 3. Furthermore,
the catalyst demonstrated excellent catalytic efficiency during the five cycles. One-pot method of phosphomolybdic acid base melamine provides a new idea for the synthesis of catalysts with outstanding catalytic properties for oxidative desulfurization (ODS).
Green Synthesis, Chemical Characterization, Antioxidant, Cytotoxicity and Anticancer Effects of Vanadium Nanoparticles
Authors: Li Yi , Li Feifei , Zhao Liying
Published: May 2024

Silybum marianum is a plant with many remedial properties and may help prevent the cancer spread. Studies in this field show that this plant can reduce the growth of cancer cells. Probably, Silybum marianum will improve the effectiveness of chemotherapy. Also, the side
effects of the recent treatments may be reduced by using this plant. The Food and Drug Administration has not confirmed Silybum marianum for the cancer treatment, but it may be effective in the treatment of these cancers: prostate, breast, cervical, blood, small intestine, and skin.
Researching formulation of metallic nanoparticles by medicinal plants is the research priority of all countries. In the current experiment, we synthesize the vanadium nanoparticles by the watery extract of the Silybum marianum aerial parts. The characterization was conducted by field
emission scanning electron microscopy, transmission electron microscopy, X-ray diffraction analysis, fourier transform infrared, energy-dispersive X-ray spectroscopy, and ultraviolet–visible spectroscopy. The DPPH inhibition efficacy was assessed by the DPPH examination, while the MTT
assay was used to evaluate anti-cervical cancer (against LM-MEL-41, HT-3, Ca Ski, DoTc2 4510, SiHa, and C-33 A cells) and cytotoxicity efficacy of vanadium NPs. In XRD, the signals at 2 theta values of 25.13, 27.77, 44.94, 49.52, 66.28, and 70.57 belong to the planes of (202), (103), (401),
(205), (406), and (125) respectively. Based on the findings of FE-SEM, the NPs are formed with the morphology of spherical with an aggregation. In FT-IR, the peaks at 416 and 551 cm−1 can be assigned to V–O–V and V–O bonds. The EDS analysis confirms the vanadium
presence by the signals at 5.45 (VKβ), 4.98 (VKα), and 0.53 (VLα). The other signals below 0.5 KeV verify the appearance of carbon and oxygen in the green synthetic vanadium nanoparticles. The V nanoparticles IC50 was 126, 157, 165, 125, 132,
and 197 μg/mL against LM-MEL-41, HT-3, DoTc2 4510, C-33 A, SiHa, and Ca Ski cervical cancer cells, respectively.
Studies on the Selectivity Between O-Alkylation versus C-Alkylation of Phenol with Cyclohexene Using Nanocrystalline Beta Zeolite
Authors: Alharbi Khadijah H.
Published: May 2024

The alkylation of phenol with cyclohexene using acid catalysts results in the generation of both O-alkylated and C-alkylated products, all of which hold significant utility across diverse industries. Cyclohexyl phenyl ether is utilized as a fragrant compound in perfumery applications.
Through dehydrogenation, it transforms into diphenyl oxide (DPO), a significant chemical intermediate. In the current research nanocrystalline zeolite Beta was synthesised by vacuum-concentration coupled hydrothermal technique using tetraethyllammonium hydroxide templates and the catalytic
performance was analysed for the alkylation of phenol with cyclohexene. Various parameters like reactant mole ratio, catalyst amount and temperature were assessed for better conversion of cyclohexene and desired product selectivity. The findings demonstrate that the catalyst effectively improves
the conversion of cyclohexene while enhancing the selectivity of desired products. High efficiency of the catalyst is attributed due to its favourable structural characteristics, including its nano sized particles with open pore structure. The catalyst displayed up to ~96% conversion of cyclohexene
~55% selectivity towards the major product, cyclohexyl phenyl ether at optimal reaction conditions. Activation energy of the phenol alkylation with cyclohexene was calculated from the measured rate constant at various temperatures and was found to be 22.9 kJ/mol. There is negligible decline
in percent conversion after reusing the catalyst for up to five runs.
On some early Latin European measurements of the eccentricity of the solar orbit (1308–1314)
Authors: Nothaft C. Philipp E.
Published: May 2024

Manuscripts in Oxford and Erfurt preserve evidence of the earliest known efforts made in Latin Europe to remeasure the eccentricity and maximum equation of the Ptolemaic solar model. The present article analyses and contextualizes this evidence, while also revisiting Ernst Zinner’s hypothesis according to which the relevant observations were made by Alard of Diest ( fl.1308).
Bibliometric Mapping of Psychological Flexibility Research: Trends and Future Directions
Authors: Wider Walton , Ping Pang Nicholas Tze , Lin Jiaming , Fauzi Muhammad Ashraf , Jiang Leilei , Tanucan Jem Cloyd M.
Published: May 2024

In this article, we offer an exhaustive analysis of academic work on psychological flexibility using bibliometric techniques. We identify emerging trends in a dataset of 3535 scholarly articles from the Web of Science database. We highlight key publications, map out the field’s intellectual framework, and anticipate future research avenues through co-citation and co-word analytics. The co-citation assessment revealed five distinct clusters, while the co-word analysis showed three. Although research regarding psychological flexibility has gained recent popularity, there remains a need for more scholarly initiatives to achieve a nuanced understanding of this subject.
Certificate of Need Laws in Health Care: Past, Present, and Future
Authors: Mitchell Matthew D.
Published: May 2024

Certificate of need (CON) laws limit the supply of health care services in about two-thirds of U.S. states. The regulations require those who wish to offer new services or expand existing services to first prove to a regulator that the care is needed. While advocates for the regulation have offered several rationales for its continuance, the balance of evidence suggests that the rules protect incumbent providers from competition at the expense of patients, payors, and would-be competitors. In this article, I review the history of CON laws in health care, summarize the large literature evaluating them, and briefly sketch options for reform.

JEL Classification: I11, I18, H75
Measurement of Visitors’ Subjective and Objective Emotional Response to Congestion in Public Spaces
Authors: Mashkov Rotem , Shoval Noam
Published: May 2024

Research on the ties between congestion and visitors’ experiences in a destination has primarily used subjective methods. The current study proposes that the emotional, subjective visitor response to congestion be measured alongside the objective experience, in real time and real-world conditions. To do so, advanced tracking methods in time and space (GPS) were combined with the Experience Sampling Method (ESM), which includes self-reporting and physiological monitoring of electrodermal activity (SCL). An intra-subject experiment was designed, with all participants asked to traverse an identical path in Jerusalem’s main market, Mahane Yehuda, under two different crowding conditions. The partial concordance between subjective and objective arousal highlights the methodology’s significance for increasing our understanding of a visit’s emotional dimension in urban destinations, particularly congested public spaces. Alongside the study’s limitations, the practical application of the methodology for tourist destinations and urban settings that face congestion and overcrowding is discussed, aiming to improve the quality of the visitor experience and urban well-being.
Air–ground cooperative multi-target searching under an unknown urban environment
Authors: Huang Chaochun , Du Bin , Chen Mou
Published: May 2024

The collaboration of heterogeneous multiple robots has been shown to be capable of significantly enhancing the system redundancy, autonomy, robustness, and so on. However, realizing the collaboration with specific tasks in practice often requires the development of sophisticated mechanisms which are envisioned to exploit distinct benefits of the heterogeneous platforms. Thus, we propose a novel air–ground cooperative framework in this paper for the task of multi-target searching under an unknown urban environment. In particular, a group of unmanned aerial vehicles (UAVs) is employed to operate above the urban area to provide surveillance from a global perspective. Under the guidance of UAVs, multiple teams of unmanned ground vehicles (UGVs) are deployed to conduct the target searching missions. The UAVs’ and UGVs’ searching strategies are devised correspondingly leveraging on their own advantageous features. Finally, an ingenious integration of UAVs’ and UGVs’ searching operations is established by a notion of the upper confidence bound. Simulation results are provided to demonstrate the effectiveness of our approach.
Legal Repair: Domesticating European Legislation on Pig Welfare
Authors: Billows Sebastian , Déplaude Marc-Olivier
Published: May 2024

Our daily activities rely on a proliferating number of things that are subject to decay. As stressed in a growing body of literature, repair is critical to the smooth functioning of material infrastructure. However, this scholarship has overlooked a crucial dimension: things become fragile not only due to material degradation but also as a result of regulatory change. This article introduces the notion of “legal repair” to describe how, in the face of legal change, certain actors reassemble the material world. We elaborate on this concept through an analysis of the domestication of European Union (EU) animal welfare legislation by the French pig sector. While it was feared that stricter pig housing standards would fragilize the existing farms, pig farmers complied using technical systems that failed to significantly improve animal welfare. We analyze this domestication of EU legislation as a process of legal repair. Alongside the political work of the leaders of the pig sector, agricultural advisers also played a key role. Their work reveals the relational nature of legal repair: in the production of “local specifications” matching the demands of existing farming systems, in the negotiation of the finer points of the legislation, and in the redefinition of farming performance.
Outcomes of chemotherapy/chemoradiation vs. R2 surgical debulking vs. palliative care in nonresectable locally recurrent rectal cancer
Authors: Sorrentino Luca , Scardino Andrea , Battaglia Luigi , Vigorito Raffaella , Sabella Giovanna , Patti Filippo , Prisciandaro Michele , Daveri Elena , Gronchi Alessandro , Belli Filiberto , Guaglio Marcello
Published: May 2024

Locally recurrent rectal cancer is resected with clear margins in only 50% of cases, and these patients achieve a three-year survival rate of 50%. Outcomes and therapeutic strategies for nonresectable locally recurrent rectal cancer have been much less explored. The aim of the study was to assess the three-year progression-free survival and the three-year overall survival in locally recurrent rectal cancer patients treated by chemotherapy/chemoradiation only vs. chemotherapy/chemoradiation and R2 surgical debulking vs. palliative care. A total of 86 patients affected by nonresectable locally recurrent rectal cancer were included: three-year progression-free survival was 15.8% with chemotherapy/chemoradiation vs. 20.3% with R2 surgical debulking (Log-rank p=0.567), but both rates were higher than best palliative care (0.0%, Log-rank p=0.0004). Three-year overall survival rates were respectively 62.0%, 70.8% and 0.0% (Log-rank p<0.0001). Chemotherapy/chemoradiation (HR 0.33, p=0.028) and R2 surgical debulking with or without chemotherapy/chemoradiation (HR 0.23, p=0.005) were independent predictors of improved progression-free survival on multivariate analysis. In conclusion, both chemotherapy/chemoradiation alone and R2 surgery with or without chemotherapy/chemoradiation provide a survival benefit over palliative care in nonresectable locally recurrent rectal cancer. However, considering that pelvic debulking is burdened by a high rate of complications, and considering its negligible impact on progression-free survival and overall survival when associated to medical therapy, surgery should be avoided in this setting.
Hydrogels in biosensing and medical diagnostics
Authors: Omidian Hossein , Chowdhury Sumana Dey , Akhzarmehr Arnavaz
Published: May 2024

This article presents an in-depth examination of recent advancements in medical and biotechnological sensing technologies, focusing on the forefront of innovation in hydrogel-based sensors within the domains of biomedical engineering and regenerative medicine. It delves into cutting-edge sensing technologies that facilitate non-invasive glucose monitoring, highlights progress in the development of intelligent solutions for wound care, and discusses the application of optical and fluorescence-based sensors for real-time diagnostics within the body. Further, it reviews the latest glucose monitoring devices, alongside wearable and implantable sensors designed for the continuous monitoring of health, including the measurement of physiological strain and stress. The exploration extends to the latest in non-invasive and minimally invasive technologies for ongoing health assessment, and to imaging and visualization techniques critical for medical diagnostics and therapeutic procedures. These advancements mark a pivotal move toward more efficient, precise, and patient-focused healthcare technologies, signaling new avenues for diagnosis, monitoring, and treatment in the healthcare sector.
Flexural–torsional buckling with enforced axis of twist and related problems
Authors: Coman Ciprian D , Bassom Andrew P
Published: May 2024

The classical lateral–torsional instability of a cantilever beam with continuous elastic lateral restraint and a transverse point-load applied at the free end is discussed here through the lens of asymptotic simplifications. One of our main goals is to provide analytical approximations for the critical buckling load, as well as its dependence on various key non-dimensional groups. The first part of this study is concerned with a scenario in which a doubly symmetric beam is constrained to rotate about a fixed axis situated at an arbitrary height above the shear centroidal axis. The second part examines a beam that features a continuous elastic lateral restraint spanning its entire length. Assuming that the stiffness of the constraint, [Formula: see text] (say), is finite, the buckling equations in the second case are described by a system of two coupled fourth-order differential equations in the lateral displacement and the angle of twist. We show that as [Formula: see text], the problem discussed in the first part provides an outer solution for the aforementioned system; the relevant boundary conditions for the next-to-leading-order outer approximation are also derived using matched asymptotics. Our theoretical findings are confirmed by comparisons with direct numerical simulations of the full buckling problem.
Unpacking Single Men’s Constructions of Innocent Men and Culpable Women in a #MeToo Context
Authors: Pickens Chelsea , Braun Virginia
Published: May 2024

The #MeToo movement became an important historical moment around the globe, illuminating the pervasive spectrum of sexual harm. This, however, did not exist without significant backlash, backlash which became one of the defining features of our study with men. We individually interviewed 31 single, heterosexual men about their experiences and understandings of contemporary masculinity, singleness and heterosexuality. During this process, participants talked significantly about the #MeToo movement and women’s accounts of sexual violence, with a focus on the implications this might have for men and dating. Using a critical discursive approach, our analysis of men’s talk was patterned by three interpretive repertoires: I just don’t understand…; You can’t do anything anymore!; and She’s really only got herself to blame… Our analysis suggests that while #MeToo has succeeded in starting a conversation about sexual violence, work still needs to be done in interrupting traditional victim-blaming discourses, as exemplified though our data.
Identifying Potential Determinants of Faecal Contamination on Domestic Floors in Three Settings in Rural Kenya: A Mixed Methods Analysis
Authors: Legge Hugo , Kazungo Karisa , Muli Sharon , Elson Lynne , Mwongeli Jacinta , Halliday Katherine E , Ochwal Victoria , Oswald William , Dreibelbis Robert , Njomo Doris , Mwandawiro Charles , Fillinger Ulrike , Pullan Rachel , Kepha Stella
Published: May 2024

Observational evidence suggests that household floors may be an important domain for the transmission of enteric and parasitic infections. However, little work has been done to investigate how household floors can become contaminated with human and animal faeces. This study uses a mixed methods approach to postulate the proximal and distal determinants of household floor contamination with faeces in groups of rural villages in 3 counties in Kenya (Bungoma, Kwale and Narok). Quantitative data was collected through a household census and analysed descriptively and using mixed effects logistic regression models. Qualitative data was collected through unstructured observations of daily routines and in-depth interviews. These data were analysed thematically with case memos produced for routine activities that were hypothesised to be determinants of floor contamination. Possible proximal determinants of floor contamination included; (1) animal contact with floors; (2) child faeces disposal, and; (3) floor cleaning routines. Distal determinants are suggested to be rooted in the socioeconomic, environmental, and cultural context in which households were located and included; (1) the type and number of animals owned by households; (2) presence/absence of dedicated shelters for housing animals at night, which impacted whether sleeping or cooking areas were exposed to animals; (3) Accessibility of inside spaces to poultry and other roaming animals; (4) ownership of an improved floor; (5) ability of animals to access neighbours compounds; (6) seasonal changes in weather. These results will be of use in identifying the contexts in which faecal contamination of domestic floors may be contributing towards transmission of enteric and parasitic infections and in designing effective interventions to prevent this exposure.
Numerical prediction of mean flow and acoustic field of a supersonic impinging jet
Authors: Kourbatski Konstantine A.
Published: May 2024

The three-dimensional turbulent mean flow and acoustic field of a supersonic jet impinging on a solid plate is studied computationally using the general purpose CFD code Ansys Fluent. A pressure-based coupled solver formulation with the second order weighted central-upwind spatial discretization is applied to compute transient solutions. Cold and hot jet thermal conditions are considered. Mean flow characteristics are investigated by a steady-state modeling approach. Acoustic radiation of impingement tones is simulated using a transient time-domain formulation. The effects of turbulence in steady-state are modeled by the SST k-ω turbulence model. The Wall-Modeled Large-Eddy Simulation (WMLES) model is applied to compute transient solutions. The near-wall mesh on the impingement plate is fine enough to resolve the viscosity-affected near-wall region all the way to the laminar sublayer. Nozzle-to-plate distance is parameterized in the model for automatic re-generation of the mesh and results. Steady-state predictions of hover lift loss and mean jet velocity distributions are compared with experimental data, and favorable agreement is reported. The transient solution reproduces the mechanism of impingement tone generation by the interaction of large scale vortical structures with the impingement plate. The acoustic near-field is directly resolved by Computational Aeroacoustics (CAA) to accurately propagate impingement tone waves to near-field microphone locations. Calculated impingement tone frequencies and sound pressure levels agree with experimental values.
Jet noise of a low bypass turbofan with internal mixing and external plug
Authors: Pastouchenko Nikolai N , Ramakrishnan Kishore , Morris Steven , Paliath Umesh
Published: May 2024

Jet noise generated by turbofan engines which are designed for supersonic aircraft operation is expected to remain a challenge for the aerospace industry. For civil supersonic transport, low bypass ratio engines with internal mixing and external plugs are currently seen as promising exhaust architecture to meet aircraft mission and certification requirements. Measurements of the noise from a representative low-bypass ratio long duct mixed flow with external plug exhaust configuration were made, along with corresponding steady-RANS and LES analyses. The measured data showed excess high frequency noise across a wide range of operating conditions as compared to an equivalent single stream jet, or an equivalent uniform jet with internal plug. The absolute levels of the excess noise were relatively insensitive to forward flight, and the excess noise was most dominant when the primary and secondary streams had large velocity and temperature mismatch just upstream of the internal mixer. Preliminary indications from the LES analysis also indicated that significant pressure fluctuations, at the same frequencies which are insensitive to forward flight, develop inside the nozzle as the internal shear layer from the mixer grows and gets accelerated by the external plug. Parametric study test measurements on the fan and core operating conditions were performed, providing support for the hypothesis that the excess noise is generated as the internal shear layer, starting inside the nozzle, gets accelerated by the plug and passes through the weak shock at the nozzle exit where the flow accelerates more and turns over the external plug.
Characteristics of jet noise: A synthesis
Authors: Viswanathan K
Published: May 2024

It is a distinct privilege to produce this article to honor Professor Tam, the foremost authority on jet aeroacoustics. The fundamental characteristics of jet noise have been studied for 70 years, since the pioneering work of Lighthill in the 1950s. The acoustic analogy, with many variants, has served as the leading theory for nearly 50 years. Many leading researchers in the 1970s formulated theories to interpret the measured trends from subsonic and supersonic jets, using acoustic analogy and flow features as the framework. Quadrupoles, dipoles and monopoles were believed to constitute the sources of noise. The discovery of large-scale organized structures in free shear layers and jets sparked a different avenue of thinking about their importance for noise generation. Tam was the first to clearly demonstrate that these structures are efficient generators of noise and constitute the dominant noise sources, especially in the downstream direction. Now, two schools of thought emerged on the sources of jet noise. Experimental measurements showed that the mean flow as well as the turbulence statistics exhibit a self-similarity in the mixing layer and another similarity in the fully developed jet. Based on these observations, Tam proposed that since noise is generated by the turbulence of the jet, the noise spectra generated by fine-scale and large-scale turbulence should also exhibit self-similarity. By examining a large set of supersonic jet noise data acquired at NASA Langley, Tam offered evidence that the turbulent mixing noise of high-speed jets does consist of two independent self-similar components. In this paper, experimental evidence is compiled from an extensive database that quantifies the effect of several parameters that affect jet spectra. A new scaling method is developed and extended to noise predictions for realistic dual-stream nozzle geometries. The objectives of this paper are to serve as a synthesis of noise characteristics and to focus on application to real-world problems. Results from five different experimental measurements are examined: (1) farfield spectral characteristics; (2) azimuthal and polar correlations in the farfield; (3) correlations of jet turbulence fluctuations and farfield sound; (4) measurement of source distributions with an elliptic mirror; and (5) space-time correlation measurements in the nearfield with a cage array, and nearfield-farfield correlations. Two distinctly different trends are observed in the angular ranges of 50° – ∼120° and ∼120° – 165° for all the parameters investigated with the above five approaches. The salient observations are mutually supporting, and the cumulative weight lends credence to the proposition that there are two distinct sources of turbulent mixing noise.
University Architectures Re-Invented: Re-Conceptualizing Forced Migration, Historical Consciousness, and Coalition Building in Ukraine After the Full-Scale Russian Invasion
Authors: Vitrukh Mariia , Koro Mirka
Published: May 2024

The purpose of this article is to describe the creation of displaced universities (DUs) as spaces for coalition building, resistance, and decolonial practice that have re-invented the university architecture. This article offers a multi-perspectival and historical exploration of higher education in Ukraine before and after the full-scale invasion of Russia in Ukraine on February 24, 2022, with particular focus on the coalitions around Ukrainian DUs. DUs can be seen as one form of decolonial creations, as a unique organic coalition and intellectual community. This organic coalition includes a process of social resistance, resilience, and policy, which are being shaped by people whose lives were and still are uncertain. These people affiliated with higher education created invisible connections that re-shaped the vision and relationality of DUs. The interwoven life trajectories of forced migrants, Ukrainian academics, administrators, and students who made the decision to move to mainland Ukraine and establish (in)visible DUs while continuing their work and education in Ukrainian territories under the control of the Ukrainian government.
Nasal mucosal fibroblasts produce IL-4 to induce Th2 response
Authors: Zeng Xianhai , Li Juanjuan , Liu Jiangqi , Mo Lihua , Liu Yu , Zhang Aizhi , Yang Pingchang , Kong Hui
Published: May 2024

Th2 polarization is essential for the pathogenesis of allergic rhinitis (AR). Th2 polarization's mechanism requires further understanding. IL-4 is the primary cytokine involved in Th2 response. Fibroblasts play a role in immune regulation. This study aims to elucidate the role of nasal mucosal fibroblast-derived IL-4 in the induction of Th2 responses. Nasal mucosal tissues were obtained from surgically removed samples from patients with nasal polyps, whether with or without AR. Fibroblasts were isolated from the tissues by flow cytometry cell sorting, and analyzed by RNA sequencing (RNAseq). The data from RNAseq showed that nasal fibroblasts expressed genes of GATA3, CD80, CD83, CD86, STAT6, IL2, IL4, IL5, IL6, IL13 and costimulatory factor. The data were verified by RT-qPCR. The level of gene activity was positively correlated with those of AR-related cytokines present in nasal secretions. Nasal fibroblasts release IL-4 upon activation. Nasal fibroblasts had the ability to transform naive CD4+ T cells into Th2 cells, which can be eliminated by inhibiting IL-4 receptor or CD28 in CD4+ T cells. To sum up, nasal mucosal fibroblasts produce IL-4, which can induce Th2 cell development. The data implicate that nasal fibroblasts are involved in the pathogenesis of nasal allergy.