bluuebunny/crossref_metadata_2025 huggingface dataset:
Modified creatinine index and risk for long-term infection-related mortality in hemodialysis patients: ten-year outcomes of the Q-Cohort Study
Authors: Arase Hokuto , Yamada Shunsuke , Hiyamuta Hiroto , Taniguchi Masatomo , Tokumoto Masanori , Tsuruya Kazuhiko , Nakano Toshiaki , Kitazono Takanari
Published: January 2020

Modified creatinine (Cr) index, calculated by age, sex, pre-dialysis serum Cr concentration, and Kt/V for urea, is an indicator of skeletal muscle mass in hemodialysis (HD) patients. It remains unknown whether the modified Cr index predicts infection-related mortality in this population. We investigated the association between the modified Cr index and infection-related mortality. A total of 3046 patients registered in the Q-Cohort Study, a multicenter, observational study of HD patients, were analyzed. Associations between sex-specific quartiles (Q1–Q4) of the modified Cr index and the risk for infection-related mortality were analyzed by Cox proportional hazard model. During a median follow-up of 8.8 years, 387 patients died of infection. The estimated risk for infection-related mortality was significantly higher in the lower quartiles (Q1, Q2, and Q3) than in the highest quartile (Q4) as the reference group (hazard ratios and 95% confidence intervals [CI]: Q1, 2.89 [1.70–5.06], Q2, 2.76 [1.72–4.62], and Q3, 1.79 [1.12–2.99]). The hazard ratio (95% CI) for a 1 mg/kg/day decrease in the modified Cr index was 1.18 (1.09–1.27, P < 0.01) for infection-related mortality. In conclusion, a lower modified Cr index is associated with an increased risk for long-term infection-related mortality in the HD population.
Genetic interaction screen for severe neurodevelopmental disorders reveals a functional link between Ube3a and Mef2 in Drosophila melanogaster
Authors: Straub Jonas , Gregor Anne , Sauerer Tatjana , Fliedner Anna , Distel Laila , Suchy Christine , Ekici Arif B. , Ferrazzi Fulvia , Zweier Christiane
Published: January 2020

Neurodevelopmental disorders (NDDs) are clinically and genetically extremely heterogeneous with shared phenotypes often associated with genes from the same networks. Mutations in TCF4, MEF2C, UBE3A, ZEB2 or ATRX cause phenotypically overlapping, syndromic forms of NDDs with severe intellectual disability, epilepsy and microcephaly. To characterize potential functional links between these genes/proteins, we screened for genetic interactions in Drosophila melanogaster. We induced ubiquitous or tissue specific knockdown or overexpression of each single orthologous gene (Da, Mef2, Ube3a, Zfh1, XNP) and in pairwise combinations. Subsequently, we assessed parameters such as lethality, wing and eye morphology, neuromuscular junction morphology, bang sensitivity and climbing behaviour in comparison between single and pairwise dosage manipulations. We found most stringent evidence for genetic interaction between Ube3a and Mef2 as simultaneous dosage manipulation in different tissues including glia, wing and eye resulted in multiple phenotype modifications. We subsequently found evidence for physical interaction between UBE3A and MEF2C also in human cells. Systematic pairwise assessment of the Drosophila orthologues of five genes implicated in clinically overlapping, severe NDDs and subsequent confirmation in a human cell line revealed interactions between UBE3A/Ube3a and MEF2C/Mef2, thus contributing to the characterization of the underlying molecular commonalities.
Nitrogen Fertilization Restructured Spatial Patterns of Soil Organic Carbon and Total Nitrogen in Switchgrass and Gamagrass Croplands in Tennessee USA
Authors: Li Jianwei , Jian Siyang , Lane Chad S. , Guo Chunlan , Lu YueHan , Deng Qi , Mayes Melanie A. , Dzantor Kudjo E. , Hui Dafeng
Published: January 2020

Nitrogen (N) fertilizers can potentially alter spatial distribution of soil organic carbon (SOC) and total nitrogen (TN)  concentrations in croplands such as switchgrass (SG: Panicum virgatum L.) and gamagrass (GG: Tripsacum dactyloides L.), but it remains unclear whether these effects are the same between crops and under different rates of fertilization. 13C and 15N are  two important proxy measures of soil biogeochemistry, but they were rarely examined as to their spatial distributions in soil. Based on a three-year long fertilization experiment in Middle Tennessee, USA, the top mineral horizon soils (0–15 cm) were collected using a spatially explicit design within two 15-m2 plots under three fertilization treatments in SG and GG croplands. A total of 288 samples were collected based on 12 plots and 24 samples in each plot. The fertilization treatments were no N input (NN), low N input (LN: 84 kg N ha−1 in urea) and high N input (HN: 168 kg N ha−1 in urea). The SOC, TN, SOC/TN (C: N), δ13C and δ15N were quantified and their within-plot variations and spatial distributions were achieved via descriptive and geostatistical methods. Results showed that SG generally displayed 10~120% higher plot-level variations in all variables than GG, and the plot-level variations were 20~77% higher in NN plots than LN and HN plots in SG but they were comparable in unfertilized and fertilized plots in GG. Relative to NN, LN and HN showed more significant surface trends and spatial structures in SOC and TN in both croplands, and the fertilization effect appeared more pronounced in SG. Spatial patterns in C: N, δ13C and δ15N were comparable among different fertilization treatments in both croplands. The descending within-plot variations were also identified among variables (SOC > TN > δ15N > C: N > δ13C). This study demonstrated that N fertilizations generally reduced the plot-level variance and simultaneously re-established spatial structures of SOC and TN in bioenergy croplands, which little varied with fertilization rate but was more responsive in switchgrass cropland.
Agro-Climato-Edaphic Zonation of Nigeria for a Cassava Cultivar using GIS-Based Analysis of Data from 1961 to 2017
Authors: Akinwumiju Akinola S. , Adelodun Adedeji A. , Orimoogunje Oluwagbenga I.
Published: January 2020

To investigate the optimal cultivation conditions for cassava cultivar (TMS98/0505) in Nigeria, we employed agro-ecological zoning to delineate the cultivated lands. Using GIS-based multi-criteria analysis, we researched the influence of some meteorological and soil parameters on the clone cultivation. From the multiple-parameter climato-edaphic zoning map, an average yield of 26 t ha−1 was estimated. The dry Rainforest and southern Guinea Savanna account for 80% of the favorable zones. However, with irrigation, the cultivar would yield optimally in the northern marginal zones. Further, the significant climatic parameters are sunshine hour (t = 3.292, α = 0.0064) and rainfall (t = 2.100, α = 0.0575). Thus, the potentials of a location for cassava cultivation in Nigeria largely depend on the soil conditions, sunshine hour, and rainfall. Generally, the cassava yield correlates strongly (+0.88) with the suitability map. Considering future climate variability based on the annual rainfall data, we projected an average annual rainfall range of 565–3,193 mm between 2070 and 2099. Likewise, the projected range of daily temperature for 2046–2100 is 24.57–31.94 °C. Consequently, with currently allotted farmlands, Nigeria can double her current cassava production through soil fertility enhancement and irrigation.
No ontogenetic shift in the realised trophic niche but in Batesian mimicry in an ant-eating spider
Authors: Pekár S. , Petráková Dušátková L. , Haddad C. R.
Published: January 2020

In predators an ontogenetic trophic shift includes change from small to large prey of several different taxa. In myrmecophagous predators that are also mimics of ants, the ontogenetic trophic shift should be accompanied by a parallel mimetic change. Our aim was to test whether ant-eating jumping spider,Mexcala elegans, is myrmecomorphic throughout their ontogenetic development, and whether there is an ontogenetic shift in realised trophic niche and their mimetic models. We performed field observations on the association ofMexcalawith ant species and investigated the natural prey of the ontogenetic classes by means of molecular methods. Then we measured the mimetic similarity of ontogenetic morphs to putative mimetic models. We foundMexcalais an inaccurate mimic of ants both in the juvenile and adult stages. During ontogenesis it shifts mimetic models. The mimetic similarity was rather superficial, so an average bird predator should distinguish spiders from ants based on colouration. The realised trophic niche was narrow, composed mainly of ants of different species. There was no significant difference in the prey composition between ontogenetic stages. Females were more stenophagous than juveniles. We conclude thatMexcalais an ant-eating specialist that reduces its prey spectrum and shifts ant models during ontogenesis.
Machine Learning and Network Analyses Reveal Disease Subtypes of Pancreatic Cancer and their Molecular Characteristics
Authors: Sinkala Musalula , Mulder Nicola , Martin Darren
Published: January 2020

Given that the biological processes governing the oncogenesis of pancreatic cancers could present useful therapeutic targets, there is a pressing need to molecularly distinguish between different clinically relevant pancreatic cancer subtypes. To address this challenge, we used targeted proteomics and other molecular data compiled by The Cancer Genome Atlas to reveal that pancreatic tumours can be broadly segregated into two distinct subtypes. Besides being associated with substantially different clinical outcomes, tumours belonging to each of these subtypes also display notable differences in diverse signalling pathways and biological processes. At the proteome level, we show that tumours belonging to the less severe subtype are characterised by aberrant mTOR signalling, whereas those belonging to the more severe subtype are characterised by disruptions in SMAD and cell cycle-related processes. We use machine learning algorithms to define sets of proteins, mRNAs, miRNAs and DNA methylation patterns that could serve as biomarkers to accurately differentiate between the two pancreatic cancer subtypes. Lastly, we confirm the biological relevance of the identified biomarkers by showing that these can be used together with pattern-recognition algorithms to accurately infer the drug sensitivity of pancreatic cancer cell lines. Our study shows that integrative profiling of multiple data types enables a biological and clinical representation of pancreatic cancer that is comprehensive enough to provide a foundation for future therapeutic strategies.
Annexin A8 regulates Wnt signaling to maintain the phenotypic plasticity of retinal pigment epithelial cells
Authors: Lueck Katharina , Carr Amanda-Jayne F. , Yu Lu , Greenwood John , Moss Stephen E.
Published: January 2020

Wnt signalling mediates complex cell-cellinteractions during development and proliferation. Annexin A8 (AnxA8), a calcium-dependent phospholipid-binding protein, and canonical Wnt signalling mechanisms have both been implicated in retinal pigment epithelial (RPE) cell differentiation. The aim here was to examine the possibility of cross-talk between AnxA8 and Wnt signalling, as both are down-regulated upon fenretinide (FR)-mediated RPE transdifferentiation. AnxA8 suppression in RPE cells via siRNA or administration of FR induced neuronal-like cell transdifferentiation and reduced expression of Wnt-related genes, as measured by real-time PCR and western blotting. AnxA8 gene expression, on the other hand, remained unaltered upon manipulating Wnt signalling, suggesting Wnt-related genes to be downstream effectors of AnxA8. Co-immunoprecipitation revealed an interaction between AnxA8 and β-catenin, which was reduced in the presence of activated TGF-β1. TGF-β1 signalling also reversed the AnxA8 loss-induced cell morphology changes, and induced β-catenin translocation and GSK-3β phosphorylation in the absence of AnxA8. Ectopic over-expression of AnxA8 led to an increase in active β-catenin and GSK-3β phosphorylation. These data demonstrate an important role for AnxA8 as a regulator of Wnt signalling and a determinant of RPE phenotype, with implications for regenerative medicine approaches that utilise stem cell-derived RPE cells to treat conditions such as age-related macular degeneration.
Serum gamma-glutamyltransferase activity and Parkinson’s disease risk in men and women
Authors: Yoo Dallah , Kim Ryul , Jung Yu Jin , Han Kyungdo , Shin Cheol Min , Lee Jee-Young
Published: January 2020

We evaluated serum gamma-glutamyltransferase (GGT) and the risk of Parkinson’s disease (PD). Using data from the National Health Insurance Service (NHIS) database, we constructed a cohort consisting of individuals aged above 40 years who underwent a health check-up in 2009. After excluding individuals with heavy alcohol consumption, hepatobiliary and pancreatic disorders, and a previous history of PD, each quartile group of baseline serum GGT levels was monitored for the development of PD for 7 years. Adjusted hazard ratios (HRs) for PD were estimated by Cox proportional hazard models adjusting for potential confounding variables. We additionally analyzed the possible interaction between GGT and obesity or metabolic syndrome. Among the 6,098,405 individuals who were included, PD developed in 20,895 individuals during the follow-up (0.34%, 9,512 men and 11,383 women). The top quartile of serum GGT (geometric means, 90.44 IU/L in men and 41.86 IU/L in women) was associated with a lower risk in men (adjusted HR = 0.72 (95% CI: 0.67–0.76)) and a higher risk in women (adjusted HR = 1.30 (95% CI: 1.23–1.37)) using the lower GGT quartiles as a reference. Obesity and metabolic syndrome increased PD risk in both sexes, and there was only a subadditive interaction between serum GGT and obesity in women.
Topographic Analysis of the Isthmus in Mesiobuccal and Mesial Roots of First Molars in a South Korean Population
Authors: Kang Sumi , Yu Hui-Wen , Shin Yooseok , Karabucak Bekir , Kim Sunil , Kim Euiseong
Published: January 2020

The purpose of this study was to evaluate the incidence and microscopic anatomy of the isthmus to provide more precise anatomical information about the mesiobuccal (MB) roots of the maxillary first molars and the mesial (M) roots of the mandibular first molars. Twenty-eight maxillary and 31 mandibular first molars were embedded, sectioned, stained, and observed at 30× magnification to evaluate the incidence and microscopic anatomy of the isthmus. The incidence of an isthmus 3 mm from the apex was 89.3% and 100% in the MB roots of the maxillary first molars and in the M roots of the mandibular first molars, respectively. The mean dentin thickness between the isthmus and the distal root surface was <1 mm at a distance of 3 mm from the apex in both types of roots. In this study, whenever two main canals were located in the MB roots of the maxillary first molars and in the M roots of the mandibular first molars, the likelihood of the presence of an isthmus increased. Therefore, clinicians should be aware of the thinnest dimensions in the distal surface of the MB roots of the maxillary first molars and the M roots of the mandibular first molars during nonsurgical and surgical root canal treatment.
Publisher Correction: Aggregation of poorly crystalline and amorphous components of infectious urinary stones is mediated by bacterial lipopolysaccharide
Authors: Prywer Jolanta , Torzewska Agnieszka
Published: January 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Author Correction: Real-world evidence and clinical observations of the treatment of advanced non-small cell lung cancer with PD-1/PD-L1 inhibitors
Authors: Song Peng , Zhang Jingcheng , Shang Congcong , Zhang Li
Published: January 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Author Correction: Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver
Authors: Beheshti Afshin , Chakravarty Kaushik , Fogle Homer , Fazelinia Hossein , Silveira Willian A. da , Boyko Valery , Polo San-Huei Lai , Saravia-Butler Amanda M. , Hardiman Gary , Taylor Deanne , Galazka Jonathan M. , Costes Sylvain V.
Published: January 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Analysis of multi-electron, multi-step homogeneous catalysis by rotating disc electrode voltammetry: theory, application, and obstacles
Authors: Lee Katherine J. , Gruninger Cole T. , Lodaya Kunal M. , Qadeer Saad , Griffith Boyce E. , Dempsey Jillian L.
Published: January 2020

This paper explores the utility and limitations of RDE techniques for mechanistic and kinetic analysis of homogeneous molecular catalysts that mediate multi-electron, multi-substrate redox transformations.
Sensitivity of a classic DNAzyme for Pb2+ modulated by cations, anions and buffers
Authors: Ren Wei , Huang Po-Jung Jimmy , He Meilin , Lyu Mingsheng , Wang Changhai , Wang Shujun , Liu Juewen
Published: January 2020

Both cations and anions in salt strongly affect the activity of a classic Pb2+ specific DNAzyme, which in turn can affect the sensitivity of related biosensors.
Imaging endogenous HClO in atherosclerosis using a novel fast-response fluorescence probe
Authors: Wang Beibei , Zhang Feng , Wang Shukun , Yang Ruijin , Chen Chonghao , Zhao Wei
Published: January 2020

A novel probe S-ClO was developed, which could selectively sense HClO as well as monitor HClO-induced arterial vessel inflammation.
Aggregation induced emission (AIE) active 4-amino-1,8-naphthalimide-Tröger's base for the selective sensing of chemical explosives in competitive aqueous media
Authors: Delente Jason M. , Umadevi Deivasigamani , Shanmugaraju Sankarasekaran , Kotova Oxana , Watson Graeme W. , Gunnlaugsson Thorfinnur
Published: January 2020

The 4-amino-1,8-naphthalimide Tröger's base based AIE-active supramolecular scaffold was synthesized and employed as a highly selective and sensitive fluorescent sensor for nitroaromatic explosives sensing in competitive aqueous media.
Niacin-ligated platinum(iv)–ruthenium(ii) chimeric complexes synergistically suppress tumor metastasis and growth with potentially reduced toxicityin vivo
Authors: Shu Liwei , Ren Lulu , Wang Yuchen , Fang Tao , Ye Zhijian , Han Weidong , Chen Chao , Wang Hangxiang
Published: January 2020

The chimeric Pt(iv)–Ru(ii) complex was designed to simultaneously release cytotoxic cisplatin and an antimetastatic Ru(ii)–arene compound, thereby producing potent anticancer activity with high drug tolerability in animals.
Flash nanoprecipitation of ultra-small semiconducting polymer dots with size tunability
Authors: He Yuezhen , Fan Xinyue , Sun Jian , Liu Rui , Fan Zhen , Zhang Zhijie , Chang Xin , Wang Baojuan , Gao Feng , Wang Lun
Published: January 2020

Schematic illustration of Pdots produced by FNP.
Hydrothermal synthesis of ZnO nanostructures with controllable morphology change
Authors: Gerbreders Vjaceslavs , Krasovska Marina , Sledevskis Eriks , Gerbreders Andrejs , Mihailova Irena , Tamanis Edmunds , Ogurcovs Andrejs
Published: January 2020

Optimal synthesis parameters for hydrothermal growth of nine ZnO nanostructure morphologies as a durable, homogeneous coating have been determined.
Controllable growth of transition metal dichalcogenide multilayer flakes with kirigami structures
Authors: Wang Xiangzhuo , Yang Huixia , Zheng Jingchuan , Li Yongkai , Peng Xianglin , Qiao Lu , Wang Zhiwei , Wang Qinsheng , Han Junfeng , Xiao Wende
Published: January 2020

2D TMDCs with triangular-shaped and hexagonal-shaped kirigami structures are grown on amorphous SiO2 substrates by chemical vapor deposition (CVD).
New 1D diorganotin(iv) dithiolate coordination polymers: crystallographic, computational, Hirshfeld surface and thermal analyses
Authors: Singh Pooja , Singh Amita , Singh Ayushi , Singh Ashish Kumar , Kociok-Köhn Gabriele , Alowais Ahmad , Abduh Naaser A. Y. , Muddassir Mohd. , Kumar Abhinav
Published: January 2020

Three new 1D coordination polymers of diorganotin(iv) dithiolates synthesized and the nature of their weak interactions addressed using computational techniques.
Lithium migration pathways at the composite interface of LiBH4and two-dimensional MoS2enabling superior ionic conductivity at room temperature
Authors: Liu Zhixiang , Xiang Mengyuan , Zhang Yao , Shao Huaiyu , Zhu Yunfeng , Guo Xinli , Li Liquan , Wang Hui , Liu Wanqiang
Published: January 2020

A novel interface with high Li-ion conductivity has been formulated and the results have been verified by DFT calculations.
Influence of the interfacial interaction strength on the viscoelasticity of hard–soft block copolymer based nanocomposites: a molecular dynamics simulation study
Authors: Zhao Ruiqi , Wang Yu , Gong Xinglong
Published: January 2020

The evolution of the polymer–nanofiller interface and hard domains during deformation was characterized by molecular dynamics simulations.
First-principles comparative study of perfect and defective CsPbX3 (X = Br, I) crystals
Authors: Evarestov R. A. , Kotomin E. A. , Senocrate A. , Kremer R. K. , Maier J.
Published: January 2020

This paper presents first principles Density Functional Theory hybrid functional calculations of the atomic and electronic structure of perfect CsPbI3, CsPbBr3 and CsPbCl3 crystals, as well as defective CsPbI3 and CsPbBr3 crystals.
Nonvolatile ferroelectric field effect transistor based on a vanadium dioxide nanowire with large on- and off-field resistance switching
Authors: Zhang Yanqing , Xiong Weiming , Chen Weijin , Luo Xin , Zhang Xiaoyue , Zheng Yue
Published: January 2020

We fabricate a ferroelectric field effect transistor (FeFET) based on a semiconducting vanadium dioxide (VO2) nanowire (NW), and we investigate its electron transport characteristics modulated by the ferroelectric effects.
Computer simulation study of fluorocarbon phosphate surfactant based aqueous reverse micelle in supercritical CO2: roles of surfactant functional groups, ionic strength, and phase changes in CO2
Authors: Shim Youngseon
Published: January 2020

Structural and dynamic properties of an aqueous micelle organized from fluorocarbon phosphate surfactant molecules in supercritical carbon dioxide are investigated via molecular dynamics computer simulations.
On the development of a gold-standard potential energy surface for the OH− + CH3I reaction
Authors: Tasi Domonkos A. , Győri Tibor , Czakó Gábor
Published: January 2020

We develop the first accurate full-dimensional ab initio PES for the OH− + CH3I SN2 and proton-transfer reactions treating the failure of CCSD(T) at certain geometries.
One-step synthesis of a robust and anti-oil-fouling biomimetic cactus-like hierarchical architecture for highly efficient oil/water separation
Authors: Zhu Lei , Li Hui , Yin Yingying , Cui Zhaozhen , Ma Chao , Li Xiaofang , Xue Qingzhong
Published: January 2020

It is of great significance to develop novel superhydrophilic/underwater superoleophobic materials using a facile and simple method for efficiently separating oily wastewater.
Catalyst-free selective N-formylation and N-methylation of amines using CO2 as a sustainable C1 source
Authors: Zou Qizhuang , Long Guangcai , Zhao Tianxiang , Hu Xingbang
Published: January 2020

We herein describe catalyst-free selective N-formylation and N-methylation of amines using CO2 as a sustainable C1 source.
Borate chemistry inspired by cell walls converts soy protein into high-strength, antibacterial, flame-retardant adhesive
Authors: Gu Weidong , Li Feng , Liu Xiaorong , Gao Qiang , Gong Shanshan , Li Jianzhang , Shi Sheldon Q.
Published: January 2020

Borate chemically cross-linked soy protein to prepare high-strength, antibacterial, flame-retardant bio-adhesive.
Construction of 3D native elemental maps for large biological specimens using LA-ICP-MS coupled with X-ray tomography
Authors: Marillo-Sialer Estephany , Black Jay R. , Paul Bence , Kysenius Kai , Crouch Peter J. , Hergt Janet M. , Woodhead Jon D. , Hare Dominic J.
Published: January 2020

Integration of quantitative elemental distributions with structural information, allowing novel insights into how tissue development is associated with a dynamic chemical environment.
Microfluidic screening system based on boron-doped diamond electrodes and dielectrophoretic sorting for directed evolution of NAD(P)-dependent oxidoreductases
Authors: Goto Haruna , Kanai Yuki , Yotsui Arisa , Shimokihara Shota , Shitara Shunya , Oyobiki Ryo , Fujiwara Kei , Watanabe Takeshi , Einaga Yasuaki , Matsumoto Yoshinori , Miki Norihisa , Doi Nobuhide
Published: January 2020

We developed μTAS for screening of NAD(P)-dependent oxidoreductases whose activity can be detected with boron-doped diamond electrodes and whose genes can be recovered by dielectrophoretic sorting of nanoliter-size droplets.
Fabrication of dual catalytic microcapsules by mesoporous graphitic carbon nitride (mpg-C3N4) nanoparticle–enzyme conjugate stabilized emulsions
Authors: Varshney Rohit , Kumar Sushil , Ghosh Kaushik , Patra Debabrata
Published: January 2020

Dual catalytic microcapsules (MCs) were fabricated by simultaneous self-assembly and cross-linking of mpg-C3N4 nanoparticles (NPs) and lipase conjugates at oil–water interface.
Fabrication of a novel Ni3N/Ni4N heterojunction as a non-noble metal co-catalyst to boost the H2 evolution efficiency of Zn0.5Cd0.5S
Authors: Jin Zhanbin , Wei Tingting , Li Fengyan , Zhang Qiu , Xu Lin
Published: January 2020

NixN/Zn0.5Cd0.5S composites displayed better photocatalytic hydrogen production from water in comparison with pristine Zn0.5Cd0.5S (ZCS), as well as Pt/ZCS and Ni3N/ZCS.
An in situ rewritable electrically-erasable photo-memory device for terahertz waves
Authors: Xiong Luyao , Liu Bin , Liu Dandan , Lv Longfeng , Hou Yanbing , Shen Jingling , Zhang Bo
Published: January 2020

A terahertz read-only in situ electrically-erasable rewritable photo-memory device based on a perovskite:Ag (perovskite with Ag nanoparticles added)/SnO2/PEDOT:PSS hetero-junction structure is reported.
Controllable and robust dual-emissive quantum dot nanohybrids as inner filter-based ratiometric probes for visualizable melamine detection
Authors: Wang Jing , Liu Xinyue , Huang Liang , Jin Jiening , Jiang Chenxing , Li Daquan , Wen Huimin , Hu Jun
Published: January 2020

A reliable ratiometric nanoprobe with two reversible fluorescent signal changes has been constructed for high-sensitivity visual melamine quantification.
Orientational DNA binding and directed transport on nanomaterial heterojunctions
Authors: Deng Ye , Wang Fuxin , Liu Yang , Yang Yanmei , Qu Yuanyuan , Zhao Mingwen , Mu Yuguang , Li Weifeng
Published: January 2020

Directional DNA transporting is realized by formation of in-plane nanomaterial heterojunction where the DNA maintains a stable helix structure. This phenomenon could guide the future studies of design of functional nano-heterojunctions for biomedical applications.
Enhanced activity of vancomycin by encapsulation in hybrid magnetic nanoparticles conjugated to a cell-penetrating peptide
Authors: Zhang Wenjie , Taheri-Ledari Reza , Hajizadeh Zoleikha , Zolfaghari Ehsan , Ahghari Mohammad Reza , Maleki Ali , Hamblin Michael R. , Tian Ye
Published: January 2020

We describe a novel antibiotic delivery system based on magnetic nanoparticles (NPs) conjugated to a cell-penetrating peptide (CPP).
From metal–organic frameworks to porous carbon materials: recent progress and prospects from energy and environmental perspectives
Authors: Wang Jing , Wang Yuelin , Hu Hongbo , Yang Qipeng , Cai Jinjun
Published: January 2020

Transforming MOFs into metal-free carbons is bringing the novel potential for MOFs to achieve industrialization owing to their with highly crystalline porous structures, showing great potential on the energy storage and environmental applications.
Multifunctional tryptophan-based fluorescent polymeric probes for sensing, bioimaging and removal of Cu2+ and Hg2+ ions
Authors: Choudhury Neha , Ruidas Bhuban , Saha Biswajit , Srikanth Kambalapalli , Das Mukhopadhyay Chitrangada , De Priyadarsi
Published: January 2020

Fluorescent polymeric probes were synthesized by amalgamating tryptophan and pyridine side-chain moieties through an imine bond with the aim of selectively sense and remove both Cu2+ and Hg2+ ions from aqueous media.
Degradation of a series of fluorinated acrylates and methacrylates initiated by OH radicals at different temperatures
Authors: García P. Lugo , Rivela C. B. , Gibilisco R. G. , Salgado S. , Wiesen P. , Teruel M. A. , Blanco M. B.
Published: January 2020

Rate coefficients for the gas-phase reactions of OH radicals with a series of fluorinated acrylates and methacrylates have been measured for the first time as a function of temperature in the range 290–308 K.
Recent developments in the synthesis of regioregular thiophene-based conjugated polymers for electronic and optoelectronic applications using nickel and palladium-based catalytic systems
Authors: Amna Bibi , Siddiqi Humaira Masood , Hassan Abbas , Ozturk Turan
Published: January 2020

Thiophene-based conjugated polymers are important conjugated polymers due to their exceptional optical and conductive properties, over the past few decades many researchers have designed novel strategies to reach more efficient materials for electronic applications.
Synthesis of a GaOOH/ZnBiTaO5heterojunction photocatalyst with enhanced photocatalytic performance toward enrofloxacin
Authors: Huang Panqi , Luan Jingfei
Published: January 2020

A GaOOH/ZnBiTaO5heterojunction photocatalyst was synthesized innovatively and characterized by XRD, SEM-EDS, XPS, FT-IR, PL and UV-Vis DRS to analyse the structural and morphological properties of the GaOOH/ZnBiTaO5heterojunction photocatalyst.
Understanding the correlation between structure and dynamics of clocortolone pivalate by solid state NMR measurement
Authors: Dey Krishna Kishor , Gayen Shovanlal , Ghosh Manasi
Published: January 2020

Structural characteristics of clocortolone pivalate are unique in the topical corticosteroid field having high penetration power through the stratum corneum of skin as well as low corticosteroid-related adverse effects.
Graphene oxide–iridium nanocatalyst for the transformation of benzylic alcohols into carbonyl compounds
Authors: Chen Tsun-Ren , Lin Yi-Sheng , Wang Yu-Xiang , Lee Wen-Jen , Chen Kelvin H.-C. , Chen Jhy-Der
Published: January 2020

Graphene oxide–iridium nanostructure act as a robust catalyst exhibiting high activity and reliability for the selective transformation of benzylic alcohols into aromatic aldehydes or ketones.
Synthesis and model simulation of the hexagonal to circular transition of perovskite cesium lead halide nanosheets by rapidly changing the temperature
Authors: Lin Zhong-Hai , Gao Fei , Chen Hong , Lei Jia-Yi , Yang Zhi , Cai Jun-Wei , Wang Ping-Jian , Wang Ming-Qiang
Published: January 2020

Lead halide perovskites have emerged as promising optoelectronic materials due to their excellent efficiencies in photovoltaic and light-emitting applications.
Design, synthesis and in vitro biological evaluation of isoxazol-4-carboxa piperidyl derivatives as new anti-influenza A agents targeting virus nucleoprotein
Authors: Pei Shuchen , Xia Shihao , Yang Fating , Chen Junlin , Wang Mengdie , Sun Wanlin , Li Ziqiang , Yuan Kangyao , Chen Jun
Published: January 2020

The work demonstrates the synthesis and biological evaluation of a new series of isoxazol-4-carboxa piperidyl derivatives.
PLGA nanoparticle preparations by emulsification and nanoprecipitation techniques: effects of formulation parameters
Authors: Hernández-Giottonini Karol Yesenia , Rodríguez-Córdova Rosalva Josefina , Gutiérrez-Valenzuela Cindy Alejandra , Peñuñuri-Miranda Omar , Zavala-Rivera Paul , Guerrero-Germán Patricia , Lucero-Acuña Armando
Published: January 2020

This study presents the influence of the primary formulation parameters on the formation of poly-dl-lactic-co-glycolic nanoparticles by the emulsification-solvent evaporation, and the nanoprecipitation techniques.
Efficiently self-healing boronic ester crystals
Authors: Commins Patrick , Al-Handawi Marieh B. , Karothu Durga Prasad , Raj Gijo , Naumov Panče
Published: January 2020

Organic crystal is described that can be bent plastically and twisted elastically, and can self-heal to 67%, an efficiency that is an order-of-magnitude higher compared to the only previously reported example.
Suppression of hydroxylation on the surface of colloidal quantum dots to enhance the open-circuit voltage of photovoltaics
Authors: Song Jung Hoon , Kim Taewan , Park Taiho , Jeong Sohee
Published: January 2020

Suppression of hydroxylation on quantum dot surfaces demonstrated a solar cell efficiency of 11.6% with the synthesis cost down up to 59.3%.
Photocatalytic hydrogen evolution on a high-entropy oxide
Authors: Edalati Parisa , Wang Qing , Razavi-Khosroshahi Hadi , Fuji Masayoshi , Ishihara Tatsumi , Edalati Kaveh
Published: January 2020

A two-phase high-entropy oxide with orange color and good light absorbance is introduced as a photocatalyst for hydrogen production.
Ultra-highly conductive hollow channels guided by a bamboo bio-template for electric and electrochemical devices
Authors: Pandoli Omar G. , Neto Reginaldo J. G. , Oliveira Natália R. , Fingolo Ana C. , Corrêa Cátia C. , Ghavami Khosrow , Strauss Mathias , Santhiago Murilo
Published: January 2020

Bamboo-based devices! A new method to fabricate silver conductive coatings into the inner walls of bamboo vascular bundles is disclosed. The hollow conductive microchannels enabled the development of new electrical and electrochemical devices.
pH-Responsive metal–organic framework encapsulated gold nanoclusters with modulated release to enhance photodynamic therapy/chemotherapy in breast cancer
Authors: Zhang Luyun , Gao Yang , Sun Sijia , Li Zihou , Wu Aiguo , Zeng Leyong
Published: January 2020

AuNCs@MOF-DOX nanocomposites as pH-responsive bi-functional nanoprobes for enhanced synergistic PDT/chemotherapy by the structural collapse of ZIF-8 in acidic medium.
Utilizing Diels–Alder “click” chemistry to functionalize the organic–organic interface of semiconducting polymers
Authors: Burmeister David , Ahrens Lukas , Opitz Andreas , Ligorio Giovanni , Hermerschmidt Felix , Jänsch Daniel , Freudenberg Jan , Bunz Uwe H. F. , Müllen Klaus , List-Kratochvil Emil J. W.
Published: January 2020

An all-solution-based modular functionalization of a cross-linked polymer semiconductor interface is presented. The thus covalently introduced moieties can be utilised for tailor-made organic–organic interfaces in organic optoelectronic devices.
Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR
Authors: Wang Fei , Wang Chunxi , Liu Yaping , Lan Wenxian , Han Hao , Wang Renxiao , Huang Shaohua , Cao Chunyang
Published: January 2020

Colchicine specifically interacts with oncogene RET G-quadruplex DNA, which advances the design of G4-interacting small molecules to treat RET-related cancers.
Photothermal conversion assisted photocatalytic hydrogen evolution from amorphous carbon nitrogen nanosheets with nitrogen vacancies
Authors: Yan Bo , Du Chun , Lin Zhaoyong , Yang Guowei
Published: January 2020

Photothermal conversion can accelerate the drift velocity of photo-induced carriers, and increase the carrier concentration. It suggests that photothermal conversion can greatly promotes photocatalytic hydrogen production.
Correction: Solution growth and thermal treatment of crystals lead to two new forms of 2-((2,6-dimethylphenyl)amino)benzoic acid
Authors: Hu Rong , Zhoujin Yunping , Liu Meng , Zhang Mingtao , Parkin Sean , Zhou Panpan , Wang Jianzhi , Yu Faquan , Long Sihui
Published: January 2020

Correction for ‘Solution growth and thermal treatment of crystals lead to two new forms of 2-((2,6-dimethylphenyl)amino)benzoic acid’ by Rong Hu et al., RSC Adv., 2018, 8, 15459–15470.
Correction: Solventless thermal crosslinked polymer protective layer for high stable lithium metal batteries
Authors: Kim Hyunjin , Kim Youn Sang , Yoo Jeeyoung
Published: January 2020

Correction for ‘Solventless thermal crosslinked polymer protective layer for high stable lithium metal batteries’ by Hyunjin Kim et al., Sustainable Energy Fuels, 2020, DOI: 10.1039/c9se01046g.
MiR-128 promotes osteogenic differentiation of bone marrow mesenchymal stem cells in rat by targeting DKK2
Authors: Wang Can , Qiao Xianghe , Zhang Zhuang , Li Chunjie
Published: January 2020

Bone loss caused by inflammatory disease, such as peri-implantitis, poses a great challenge to clinicians for restoration. Emerging evidence indicates that microRNAs (miRNAs) are indispensable regulators of bone growth, development, and formation. In the present study, we found that microRNA-128 (miR-128) was differentially up-regulated during the osteogenic differentiation of rat bone marrow stem cells (rBMSCs). Overexpression of miR-128 promoted osteogenic differentiation of rBMSCs by up-regulating alkaline phosphatase (ALP), matrix mineralization, mRNA, and protein levels of osteogenic makers (e.g. RUNX2, BMP-2, and COLIA1), whereas inhibition of miR-128 suppressed osteoblastic differentiation in vitro. Mechanistically, miR-128 directly and functionally targeted Dickkopf2 (DKK2), which is a Wnt signaling pathway antagonist, and enhanced Wnt/β-catenin signaling activity. Furthermore, the positive effect of miR-128 on osteogenic differentiation was apparently abrogated by DKK2 overexpression. Collectively, these results indicate that miR-128 promotes osteogenic differentiation of rBMSCs by targeting DKK2, which may provide a promising approach to the treatment of peri-implantitis.
Conceptualizing Participation and Communication Disorder in Dementia Research
Authors: Davies Katharine
Published: January 2020

Purpose

The overarching aim of this article is to explore the relating concepts of participation and communication in dementia care research and to propose future avenues of research within the field of communication disorders. Individuals with dementia comprise speech-language pathologists' largest clinical population. In the context of a growing international movement toward ending discrimination and increasing social participation of persons with dementia, understanding how communication disability and participation interact warrants attention in this field. Previous literature has yet to explore links between communication disability and social citizenship in dementia care.

Method

This is a viewpoint article. A search was performed on three literature databases, followed by a snowball technique, in order to identify relevant literature on social citizenship.

Results

Integrating a social citizenship–based understanding of participation in dementia would provide a framework for communication disorders researchers to examine systematic communicatively disabling conditions in communities and societies.

Conclusions

It is highlighted that a deeper understanding is needed of how stigmatization of both communication disability and dementia might interact to prevent the active participation of individuals with dementia.
Pathophysiology, Differential Diagnosis, and Management of Persistent Postural-Perceptual Dizziness: A Review
Authors: Holmberg Janene M.
Published: January 2020

Purpose

The purpose of this article is to review the advancing understanding, differential diagnosis, and integral role of vestibular rehabilitation (VR) in the relatively new but very common diagnosis, persistent postural-perceptual dizziness (PPPD). PPPD is a functional vestibular disorder characterized by chronic and persistent nonspinning dizziness, visual/motion hypersensitivities, and perceived unsteadiness that is often triggered from a definable peripheral vestibular disorder. PPPD is being found to be more common than many well-known peripheral vestibular disorders such as Ménière's disease or bilateral vestibular hypofunction. Early and correct identification of PPPD, including appropriately prescribed VR, is being found essential not only to promote optimal recovery but also to prevent more refractory engrained PPPD.

Conclusion

PPPD management is steadily advancing, and treating clinicians are now able to access internationally sanctioned diagnostic criteria, World Health Organization
International Classification of Diseases
,
11th Revision
(WHO, 2018) classification, and advancing treatment protocols. Treatment protocols integrate not only medications and cognitive behavioral therapy but also the crucial role of VR, including education, visual/optokinetic motion desensitization, graded habitation, balance retraining, and integrated relaxation/mindfulness.
Wave heating of the solar atmosphere without shocks
Authors: Wójcik D. , Kuźma B. , Murawski K. , Musielak Z. E.
Published: January 2020

Context. We investigate the wave heating problem of a solar quiet region and present its plausible solution without involving shock formation.

Aims. We aim to use numerical simulations to study wave propagation and dissipation in the partially ionized solar atmosphere, whose model includes both neutrals and ions.

Methods. We used a 2.5D two-fluid model of the solar atmosphere to study the wave generation and propagation. The source of these waves is the solar convection located beneath the photosphere.

Results. The energy carried by the waves is dissipated through ion-neutral collisions, which replace shocks used in some previous studies as the main source of local heating in quiet regions.

Conclusions. We show that the resulting wave dissipation is sufficient to balance radiative and thermal energy losses, and to sustain a quasi-stationary atmosphere whose averaged temperature profile agrees well with the observationally based semi-empirical model of Avrett & Loeser (2008, ApJS, 175, 229).
Algorithms of approximate dynamic programming for hydro scheduling
Authors: Parvez Iram , Shen Jianjian
Published: January 2020

In hydro scheduling, unit commitment is a complex sub-problem. This paper proposes a new approximate dynamic programming technique to solve unit commitment. A new method called Least Square Policy Iteration (LSPI) algorithm is introduced which is efficient and faster in convergence. This algorithm takes the properties of widely used algorithm least square temporal difference (LSTD), enhance it further and make it useful for optimization problems. First value function is to find a fixed policy by using least square temporal difference Q (LSTDQ) algorithm which is similar to LSTD, then LSPI is introduced for making the policy iteration algorithm by using the results of LSTDQ. It combines the data efficiency of LSTDQ and policy-search efficiency of policy iteration.
Evaluation of Unconventional Water Resources Based on Knowledge Granularity
Authors: WU Xin , Wen Qingbo , HU Liming , Liu Mingyang
Published: January 2020

Water resources are important natural resources and play a key role in economic development and social life. China is one of the countries with the most serious water shortage in the world. In the next few decades, the contradiction between supply and demand of water resources will always plague China. Increasing the use of unconventional water resources to mitigate the water crisis is necessary way to achieve a sustainable development. There has been no effective standard yet in China to evaluate the exploitation level and potential of unconventional water resources. This study describes the current status of the exploitation and aims at establishing an evaluation system incorporating the three relevant factors, namely, driving, restrictive, and risk factors respectively, and provides a theoretical basis for the management of unconventional water resources in China. In order to mine the relationship between data and evaluation indexes, the rough set theory is adopted to determine the weight and objectively reflect the importance of each evaluation index. On the basis of the evaluation system, relevant data from 2006 to 2017 in Beijing were selected, and the results show that the urgency of unconventional water resources development in Beijing was generally on the rise with a small fluctuation range.
Influence of irrigation mode on winter wheat production and moisture changes of wheat fields under extreme rainfall patterns
Authors: Li Xiaoshuang , Song Ni , Shen Xiaojun , Sun Jingsheng , Dang Hongkai
Published: January 2020

This work studied the effect of irrigation measures on water changes and crop growth in wheat fields during extreme drought years with rainfall of only 47.7 mm during the wheat growth period. Field investigation was carried out in the low plains of Hebei Province. In the experiment, six water-saving wheat varieties were used, and five irrigation levels (0 mm, 75 mm, 150 mm, 225 mm and 300 mm designated as T0, T1, T2, T3 and T4, respectively) were set in the spring. Results showed that wheat yield ranged from 70.5 kg/hm2 to 7053.0 kg/hm2. With the increase in irrigation times, yield level gradually increased and was highest under the T4 treatment. The effect of irrigation mode on panicle number was different from that on yield. The T0 treatment group had the smallest panicle number, whereas the other treatment groups showed slight differences and no discernible trend. The range of 1000-grain weight of different varieties of wheat was 33.36–46.68 g. Except for the T0 treatment, all other treatments increased with the increase in irrigation times. The difference between panicle and grain number was irregular and related to varieties. When population difference was large, yield was related to population size. When the population difference was small, yield was correlated with 1000-grain weight. From the perspective of soil water changes, in the late growth stage, the water content of deep soil under T0 and T4 treatments was higher, whereas that under T1 and T2 treatments was lower. This result indicated that T1 and T2 irrigation modes were conducive for the full utilisation of water in deep soil and were efficient water use modes. T1 and T2 were water saving irrigation models in this study. These conclusions can provide a theoretical basis for guiding the selection of irrigation patterns for wheat cultivation during spring.
Strategies for Prevention and Control of Water Pollution in Villagers’ Livestock and Poultry Breeding Industry under the Rural Revitalization Strategy
Authors: Deng Dexiang , Wen Yan , Zhou Xi
Published: January 2020

The diversified development of villagers’ livestock and poultry breeding models according to local conditions is one of the important paths for rural revitalization. Design different operation modes of livestock and poultry breeding and corresponding prevention and control of water pollution measures, establish a coordinated mechanism for villagers’ breeding and its water pollution prevention, and develop strategies for villagers’ breeding prevention and control of water pollution such as setting up harmless treatment station of dead livestock and poultry in order to achieve the goal of win-win cooperation between villagers’ interests, people’s needs and rural ecological environment.