bluuebunny/crossref_metadata_2025 huggingface dataset:
A Photothermal-Response Oxygen Release Platform Based on Hydrogel for Accelerating Wound Healing
Authors: Jin Lin , Li Chunyang , He Xiaojun , Li Qingfeng , Lv Mingzhi , Shen Jianliang , He Deyan
Published: July 2022

During wound healing, oxygen availability and anti-inflammatory microenvironment play an important role in the formation of new tissue. However, whether to provide continuous and controllable oxygen around the injured tissue while inhibiting inflammation, and realize the synergistic effect of oxygen supply and anti-inflammation, is still a major problem affecting the regeneration and repair of wound tissue. Inspired by skin wound pathology and the inflammatory microenvironment, a photothermal response-assisted strategy has been developed in this work. We prepared composite hydrogel system of PDA-HA (polydopamine-hyaluronic acid) hydrogel-loaded CaO2-ICG@LA@MnO2 (calcium peroxide-indocyanine green @ lauric acid @ manganese dioxide) nanoparticles, which showed excellent photothermal performance under near-infrared (NIR) irradiation, and realized the on-off release of oxygen and reactive oxygen species (ROS). Controlled and sustained oxygen release can promote the regeneration and repair of damaged tissue, and the generated ROS can effectively inhibit the outbreak of inflammation at the initial stage of wound healing. We believe that the system we have obtained can be used as a new approach for treating chronic wound healing.
MRSA Panophthalmitis in a Brittle Diabetic: a Histopathologic Review
Authors: Flynn Erin , Lesche Stephen , Barak Stephanie , Ittoop Sabita , Mansour Tamer , Wroblewski Keith J.
Published: July 2022

A 30-year-old male presented with bilateral eye swelling and methicillin resistant staph aureous(MRSA) bacteremia from an outside hospital. His past medical history included poorly controlled type 1 diabetes mellitus, end stage renal disease on dialysis, heart failure with reduced ejection fraction, and bilateral below the knee amputations. With worsening bilateral periorbital swelling as well as concern for intracranial involvement/spread and for scleral melt on the left eye, the patient was taken for left eye enucleation with wound drainage/antibiotic irrigation. The entire globe was represented in the slide and it shows extensive intra-ocular, scleral and episcleral acute inflammation with multifocal abscess formation. MRSA orbital cellulitis is an aggressive disease and generally caused by external trauma or injury that seeds the gram-positive organism posterior to the orbital septum, although it can also be caused endogenously through systemic infection. Bilateral blindness from community-associated MRSA orbital cellulitis has also been seen in the literature. We present a histopathologic review of a case of MRSA panophthalmitis.
The effect of ZnO nanoparticles functionalized with glutamine and conjugated with thiosemicarbazide on triggering of apoptosis adenocarcinoma gastric (AGS) cell line
Authors: Beigi Sadaf , Salehzadeh Ali , Habibollahi Hadi , Shandiz Seyed Ataollah Sadat , Safa Fariba
Published: July 2022

Purpose
Gastric carcinoma is the fourth most common malignancy worldwide and remains the second cause of death of all malignancies worldwide. Today, despite advances in treatment, cancer is still the second leading cause of death worldwide. In the meantime, nanotechnology has helped to achieve fast and effective treatment. Today, Thiosemicarbazones has emerged as a new wave of drugs in recent years. Since these compounds alone have not been very successful in treating cancer, combining them with different nanoparticles has significantly increased the chances of success.
Methods
In this study, first Zinc Oxide (ZnO) nanoparticles were synthesized and then functionalized by glutamine (Gln) and finally conjugated to Thiosemicarbazide (ZnO@Gln-TSC) by co-precipitation method. Physicochemical method including FTIR, DLS, XRD, EDS-map, Zeta-potential, field emission scanning electron microscopy (FESEM) and imaging electron microscopy (TEM) techniques were used to investigate the synthesis of ZnO@Gln-TSC nanoparticles. The toxicity effects of ZnO@Gln-TSC nanoparticles and Oxaliplatin drug at different concentrations were investigated by MTT assay on adenocarcinoma gastric (AGS) cell line and normal cell line (HEK293). Apoptosis (programmed cell death) was also evaluated by Flow cytometry (Annexin V/ PI kit), cell cycle analysis and Hoechst staining.
Results
The synthesis of ZnO@Gln-TSC nanoparticles (NPs) was confirmed by chemical confirmation tests. The size of synthesized NPs was reported in the range of 40 to 70 nm. Also, a number of -31.7 mV in the Zeta-potential test indicated the stability of the produced nanoparticle. EDS analysis showed the elements of final NPs. DLS analysis showed the size of the hydrated NP at 374 nm. MTT test showed that the IC50 of NPs was 9.8 µg/ml and Oxaliplatin drug 65.7 µg/ml for cancer cells in comparison the IC50 of 150 µg/ml for normal cells. Hoechst staining confirmed that the NPs can induce apoptosis and cell death in cancer cell line. Flow cytometry analysis showed apoptosis induction among NPs treated cells than controls with the frequency of 55.5% and 9.48% for the early and late apoptosis, respectively.
Conclusion
This study revealed the promising anticancer potential of NPs to be used for gastric cancer treatment after further characterization using in-vitro and in-vivo assays.
Mahonia alkaloids (MA) ameliorate depression induced gap junction dysfunction by miR-205/Cx43 axis
Authors: He Junhui , Li Dongmei , Wei Jie , Wang Sheng , Chu Shifeng , Zhang Zhao , He Fei , Wei Dongmei , Li Yi , Xie Jiaxiu , Wei Guining , Chen Naihong
Published: July 2022

Depression has become an important disease threatening human health. In recent years, the efficacy of Traditional Chinese Medicine (TCM) in treating the disease has become increasingly prominent, so it is meaningful to find new antidepressant TCM. Mahonia fortune (Lindl.) Fedde is a primary drug in traditional formulas for the treatment of depression, however, the exact mechanism of its action is unclear. This study aimed to research the effect of MA on the improvement of gap junction function in depression via the miR-205/Cx43 pathway. The antidepressant effects of MA were observed by a rat model of reserpine-induced depression and a model of corticosterone (CORT)-induced astrocytes. The concentrations of neurotransmitters were measured by ELISA, the expression of Connexin 43 (Cx43) protein was measured by Immunohistochemistry, the expression of Cx43, BDNF, CREB proteins were measured by western-blot, the pathological changes of prefrontal cortex were observed by hematoxylin-eosin (H&E) staining. The binding of miR-205 and Cx43 was verified with a Luciferase reporter gene. Gap junction dysfunction detected by fluorescent yellow staining. The results confirmed that MA remarkably decreased miR-205 expression and increased Cx43, BDNF, CREB expression in depression rat and CORT-induced astrocytes. In addition, after overexpression of miR-205 in vitro, MA significantly increased Cx43, BDNF and CREB expression in CORT-induced astrocytes. Thus, MA may target Cx43 through miR-205 to regulate CREB/BDNF signaling pathway to improve depressive behavior.
Discovery and Significance of Green and Selenium-Rich of Upland Rice in Xinfeng County, Jiangxi Province,China
Authors: WANG Yun , Lan yang , zou Yong-jun , qiu su-yan
Published: July 2022

Elemental selenium deficiency is considered as a global problem about the health of human that can be alleviated by daily selenium supplementation from selenium-rich foods. In order to discover some green selenium-enriched agricultural products, several samples including surface soil, upland rice and root soil collected from the camellia interplanting upland rice in Xinfeng County, Jiangxi Province were tested, analyzed for selenium and heavy metals elements, and evaluated their quality. The results show that the surface soil is strongly acidic in this area, the average selenium content grade is moderate, and the soil environmental geochemistry grade is clean. For the upland rice, it is found that the root-soil system is strong acid, the average selenium content grade is selenium-rich, and the soil environmental geochemistry grade is clean. Additionally, the vertical profile of the soil reveals that Cd, Hg, Cr, and organic matter exhibit an obvious enrichment trend on the surface, and the content of Se is positively correlated with the content of Cd, As, Hg, Cr, and organic matter respectively, while is negative with the content of Ni, Cu, Zn, Pb and pH respectively, which indicates that the upland rice is at risk of heavy metal pollution. Nervertheless, the upland rice grown in this area is green and selenium-rich, which suggests a good ability to repair the soil contaminated by Hg and Cd heavy metals through the upland rice.
Extremely reduced supergroup F Wolbachia: transition to obligate insect symbionts
Authors: Mahmood Sazzad , Nováková Eva , Martinů Jana , Sychra Oldřich , Hypša Václav
Published: July 2022

Background
Wolbachia belong to highly abundant bacteria which are frequently found in invertebrate microbiomes and manifest by a broad spectrum of lifestyles from parasitism to mutualism. Wolbachia Supergroup F is a particularly interesting group as it gave rise to symbionts of both arthropods and nematodes, and some of its members are obligate mutualists. Investigations on evolutionary transitions among the different symbiotic stages have been hampered by a lack of the known diversity and genomic data for the supergroup F members.
Results
Based on amplicon screening, short and long read WGS approaches, and laser confocal microscopy, we characterize five new supergroup F Wolbachia strains from four chewing lice species. These strains reached different evolutionary stages and represent two remarkably different types of symbiont genomes. Three of the genomes resemble other known members of Wolbachia F supergroup, while other two show typical signs of ongoing gene inactivation and removal (genome size, coding density, low number of pseudogenes). Particularly, wMeur1, a symbiont fixed in microbiomes of Menacanthus eurysternus across four continents, possesses a highly reduced genome of 733,850 bp. The horizontally acquired capacity for pantothenate synthesis and localization in specialized bacteriocytes suggest its obligate nutritional role.
Conclusions
The genome of wMeur1 strain, from the M. eurysternus micobiome, represents the smallest currently known Wolbachia genome and the first example of Wolbachia which has completed genomic streamlining as known from the gammaproteobacterial obligate symbionts. This points out that despite the large amount and great diversity of the known Wolbachia strains, evolutionary potential of these bacteria still remains underexplored. The diversity of the four chewing lice microbiomes indicates that this vast parasitic group may provide suitable models for further investigations.
Complete mitochondrial genomes and updated divergence time of the two freshwater clupeids endemic to Lake Tanganyika (Africa) suggest intralacustrine speciation
Authors: Milec Leona J.M. , Vanhove Maarten P.M. , Bukinga Fidel Muterezi , Keyzer Els L.R. , Kapepula Vercus Lumami , Mulungula Pascal Masilya , Mulimbwa N’Sibula , Wagner Catherine E. , Raeymaekers Joost A.M.
Published: July 2022

BackgroundThe hydro-geological history of Lake Tanganyika paints a complex image of several colonization and adaptive radiation events. The initial basin was formed around 9-12 million years ago (MYA) from the predecessor of the Malagarasi–Congo River and only 5-6 MYA, its sub-basins fused to produce the clear, deep waters of today. Next to the well-known radiations of cichlid fishes, the lake also harbours a modest clade of only two clupeid species, Stolothrissa tanganicae and Limnothrissa miodon. They are members of Pellonulini, a tribe of clupeid fishes that mostly occur in freshwater and that colonized West- and Central-Africa during a period of high sea levels during the Cenozoic. There is no consensus on the phylogenetic relationships between members of Pellonulini and the timing of the colonization of Lake Tanganyika by clupeids. ResultsWe use short-read next generation sequencing of 10X Chromium libraries to sequence and assemble the full mitochondrial genomes of S. tanganicae and L. miodon. We then use Maximum Likelihood and Bayesian methods to place them into the phylogeny of Pellonulini and other clupeiforms, taking advantage of all available full mitochondrial clupeiform genomes. We identify Potamothrissa obtusirostris as the closest living relative of the Tanganyika sardines and establish paraphyly for Microthrissa. Our results indicate a relatively recent divergence of the Tanganyika sardines around 4.07 MYA [95% CI: 1.66-7.06], and from P. obtusirostris around 11.88 MYA [95% CI: 6.09-17.27]. ConclusionsThese young estimates imply that the ancestor of the Tanganyika sardines diverged from a riverine ancestor and entered the proto-lake Tanganyika around the time of its formation from the Malagarasi–Congo river, and diverged into the two extant species at the onset of deep clearwater conditions. Our results prompt a more thorough examination of the relationships within Pellonulini, and the new mitochondrial genomes provide an important resource for the future study of this tribe, e.g. as a reference for species identification, genetic diversity, and macroevolutionary studies.
Translanguaging Pedagogy in Tutor’s Oral Corrective Feedback on Chinese EFL Learners’ Argumentative Writing
Authors: Wang Yibei , Li Danli
Published: July 2022

Translanguaging pedagogy has widely attracted interests from studies of second or foreign language teaching. Corrective feedback has long been recognized for its value on improving second language learning outcomes. However, limited attention has been given to the potential influence of translanguaging in the process of corrective feedback on learners’ second language writing performance, especially the influence of oral corrective feedback. This paper aims at exploring the effects of translanguaging in tutors’ oral corrective feedback (OCF) on Chinese EFL learners’ argumentative writing in six-week writing tutorials. 12 first-year Chinese college students and a Chinese tutor of English participated in the study at a university in Central China. The findings showed positive effects of translanguaging in OCF on Chinese EFL students’ argumentative writing performance. It attempts to make some contributions to EFL writing instruction. Teachers can alter their monolingual medium of English only to adapt to students’ needs, focus on students’ language practices, and create a language education ecological environment through translanguaging pedagogy.
Predictable Timing Behavior of Gracefully Degrading Automotive Systems
Authors: Weiss Philipp , Steinhorst Sebastian
Published: July 2022

Fail-operational behavior of safety-critical software for autonomous driving is essential as there is no driver available as a backup solution.In a failure scenario, safety-critical tasks can be restarted on other available hardware resources.Here, graceful degradation can be used as a cost-efficient solution where hardware resources are redistributed from non-critical to safety-critical tasks at run-time.We allow non-critical tasks to actively use resources that are reserved as a backup for critical tasks, which would be otherwise unused and which are only required in a failure scenario.However, in such a scenario, it is of paramount importance to achieve a predictable timing behavior of safety-critical applications to allow a safe operation. Here, it has to be ensured that even after the restart of safety-critical tasks a guarantee on execution times can be given.
In this paper, we propose a graceful degradation approach using composable scheduling.We use our approach to present, for the first time, a performance analysis which is able to analyze timing constraints of fail-operational distributed applications using graceful degradation.Our method can verify that even during a critical ECU failure, there is always a backup solution available which adheres to end-to-end timing constraints.Furthermore, we present a dynamic decentralized mapping procedure which performs constraint solving at run-time using our analytical approach combined with a backtracking algorithm.
We evaluate our approach by comparing mapping success rates to state-of-the-art approaches such as active redundancy and an approach based on resource availability. In our experimental setup our graceful degradation approach can fit about double the number of critical applications on the same architecture compared to an active redundancy approach.
Combined, our approaches enable, for the first time, a dynamic and fail-operational behavior of gracefully degrading automotive systems with cost-efficient backup solutions for safety-critical applications.
Predictive values of the modified Mallampati test, upper lip bite test, thyromental distance and ratio of height to thyromental distance to predict difficult laryngoscopy in pediatric elective surgical patients 5-12 years old at selected Addis Ababa governmental hospitals, Ethiopia: A multicenter cross-sectional study.
Authors: Sitot Mulualem , Amare Wubayehu , Aregawi Adugna
Published: July 2022

Background: Maintaining patent airways is vital in pediatric anesthetic management. Failure to manage and anticipate difficult laryngoscopy preoperatively is the leading cause of morbidity and mortality. Data on the predictive values of screening parameters in predicting difficult laryngoscopy (DL) are limited in children. Therefore, this study aimed to assess the predictive value of the modified Mallampati test (MMT), upper lip bite test (ULBT), thyromental distance (TMD), and ratio of height to thyromental distance (RHTMD) in predicting DL in children aged 5-12 years at selected Addis Ababa governmental hospitals in Ethiopia.Methods: A multicenter cross-sectional study was conducted on 141 elective pediatric surgical patients aged 5 to 12 years selected using a systematic random sampling technique from December 1, 2021, to April 30, 2022. Data were collected using structured questionnaires. The collected data were entered and analysed by SPSS version 26. Fisher’s exact test and receiver operating characteristic curve analysis were used to compare the accuracy of MMC, ULBT, TMD, and RHTMD against difficult laryngoscopy. A P value <0.05 was considered statistically significant.Results: The magnitude of difficult laryngoscopy was 15.6%. MMT has the highest sensitivity (86.4%), specificity (91.6%), and negative predictive value (NPV) (97.3%) compared to other tests. The ULBT also has a high sensitivity (72.7%), specificity (84%), and NPV (94.3%) with comparable diagnostic accuracy (90.8%) with the MMT (P<0.05). The sensitivity, specificity, positive predictive value (PPV), NPV, and accuracy of TMD were 63.6%, 95.8%, 73.7%, 93.4%, and 82.2%, respectively. The RHTMD has the lowest specificity (63.6%), PPV (22.5%), NPV (91.4%), and accuracy (56.7%) in predicting difficult laryngoscopy.Conclusion: The MMT and ULBT are good screening tests, followed by the TMD in predicting DL, while the RHTMD was the least accurate predictor. Because no single test has 100% predictive value, a combination of screening tests is advised in pediatrics for predicting difficult laryngoscopy.
Adenylate cyclase A amplification and functional diversification during Polyspondylium pallidum development
Authors: Kawabe Yoshinori , Schaap Pauline
Published: July 2022

Background: In Dictyostelium discoideum (Ddis) adenylate cyclase A (ACA) critically generates the cAMP oscillations that coordinate aggregation and morphogenesis. Unlike group 4 species like Ddis, other groups do not use cAMP to aggregate. However, deletion of cAMP receptors (cARs) or extracellular phosphodiesterase (PdsA) in Polyspondylium pallidum (Ppal, group 2) blocks fruiting body formation, suggesting that cAMP oscillations ancestrally control post-aggregative morphogenesis. In group 2, the acaA gene underwent several duplications. We deleted the three Ppal aca genes to identify roles for either gene and tested whether Ppal shows transient cAMP-induced cAMP accumulation, which underpins oscillatory cAMP signalling. Results: Unlike Ddis, pre-aggregative Ppal cells did not produce a pulse of cAMP upon stimulation with the cAR agonist 2'H-cAMP but acquired this ability after aggregation. Deletion of Ppal aca1, aca2 and aca3 yielded different phenotypes. aca1ˉ cells showed relatively thin stalks, aca2ˉ showed delayed secondary sorogen formation and aca3ˉ formed less aggregation centers. The aca1ˉaca2ˉ and aca1ˉaca3ˉ mutants combined individual defects, while aca2ˉaca3ˉ and aca1ˉaca3ˉaca2ˉ additionally showed >24 h delay in aggregation, with only few aggregates with fragmenting streams being formed. The fragments developed into small fruiting bodies with stalk and spore cells. Aggregation was restored in aca2ˉaca3ˉ and aca1ˉaca3ˉaca2ˉ by 2.5 mM 8Br-cAMP, a membrane-permeant activator of cAMP-dependent protein kinase (PKA). Like Ddis, Ppal sorogens also express the adenylate cyclases ACR and ACG. We found that prior to aggregation, Ddis acaˉ/ACG cells produced a pulse of cAMP upon stimulation with 2'H-cAMP, indicating that cAMP oscillations may not be dependent on ACA alone.Conclusions: The three Ppal replicates of acaA perform different roles in stalk morphogenesis, secondary branch formation and aggregation in Ppal, but act together to enable development by activating PKA. While even an aca1ˉaca3ˉaca2ˉ mutant still forms (some) fruiting bodies, suggesting little need for ACA-induced cAMP oscillations in this process, we found that ACG also mediated transient cAMP-induced cAMP accumulation. It therefore remains likely that post-aggregative Ppal morphogenesis is organized by cAMP oscillations, favouring a previously proposed model where cAR-regulated cAMP hydrolysis rather its synthesis dominates oscillatory behaviour.
WITHDRAWN: Physicochemical processes of steam reforming in small spaces
Authors: Chen Junjie
Published: July 2022

The steam reforming of hydrocarbon or alcohol fuels has attracted increasing interest in the context of the production of hydrogen. However, there is a lack of a clear concept of the critical role that energy considerations play in an accurate explanation of steam reforming in small spaces. This study relates to the physicochemical processes for producing hydrogen by the catalytic endothermic reaction of methanol with steam in a thermally integrated microchannel reforming reactor. Computational fluid dynamics simulations are conducted to better understand the consumption, generation, and exchange of thermal energy between endothermic and exothermic processes in the reactor. The effects of design factors on heat transport characteristics and reactor performance are investigated. The results indicate that uneven flows can lead to incomplete utilization or local zones of varying reaction rate and heat transfer. Poor distribution of the fluids can lead to local hot spots which can decrease the reaction selectivity, reduce catalyst life, or lead to side reactions which may lead to dangerous uncontrollable side reactions. In addition to losses in selectivity and decreased product yield, poor thermal management can decrease the life of a catalyst and further reduce the efficiency of a reactor. Since the thermally coupled reactions are so closely coupled, neither reaction can run at a significantly different reaction rate at any point along the channel length. Each reaction will exhibit a peak in reaction rate at nearly the same position within the reactor with slower reaction rates before and after this peak, which leads to the need for a long reactor channel to ensure complete conversion. Unfortunately, the exothermic reaction is difficult to control with convenient combustion catalysts and fuels, and most of the combustion occurs near the fuel inlet. This uneven combustion results in uneven heat transfer to the endothermic reaction and poor overall reactor performance. Thermally matching the reactions is still further complicated by the inherent temperature gradients that are present along the flow length of the reaction channel. Any solution directed to resolving this thermal matching problem in a parallel flow configuration will add significant complexity or mass to the system.
WITHDRAWN: Mechanistic insights into the combustion of gas mixtures in small spaces
Authors: Chen Junjie
Published: July 2022

While flame propagation of gas mixtures in small spaces is feasible, the interplay of kinetics and transport in flame stability and combustion characteristics is poorly understood. This study relates to the mechanistic insights into the combustion of gas mixtures in small spaces. Flame propagation in microchannels is modeled using two-dimensional simulations with detailed multicomponent transport, gas-phase chemistry, heat loss through the wall, radical recombination at walls, and possible temperature discontinuity at the wall due to lack of thermal accommodation. Simulations are performed to gain insights into the performance of a millimeter-scale continuous flow reactor. A dimensionless number analysis is performed to better understand the heat transfer characteristics of the millimeter-scale continuous flow reactor. The factors affecting combustion characteristics and flame stability are determined for the millimeter-scale continuous flow reactor. The results indicate that combustion in small spaces can offer many advantages. The wall thermal conductivity is vital in determining the flame stability of the reactor. Further improvement in flame stability can be achieved by using anisotropic walls. When the catalytic rate increases to such an extent that the reactants cannot be transferred to the catalytic surface fast enough to keep up with the catalytic reaction rate, the reaction shifts to mass transfer control, and the catalytic reaction rate levels off regardless of further temperature increases. Increasing the rate of mass transfer of reactants to the catalytic surfaces would result in increased pressure drop and consequently a substantial loss of energy. Catalytically-supported, thermal combustion surmounts the mass transfer limitation. Catalytically-supported thermal combustion is achieved by contacting at least a portion of the carbonaceous fuel intimately admixed with air with a solid oxidation catalyst having an operating temperature substantially above the instantaneous auto-ignition temperature of the fuel-air admixture. Combustion is no longer limited by mass transfer as in the case of conventional catalytic combustion, and at the specified operating temperatures the reaction rate is substantially increased beyond the mass transfer limitation.
Speech Quefrency Transform (SQT)
Authors: Hasanain Ahmad Zuhair , Kepuska Veton Z , Silaghi Marius Calin , Kostanic Ivica N
Published: July 2022

The fundamental frequency feature is crucial for Automatic Speech Recognition because its patterns convey a para-language and its tuning normalizes other speech features. Human speech is multidimensional because it is minimally represented by three variables: the intonation (or pitch), the formants (or timbre), and the speech resolution (or depth). These variables represent the hidden states of the local glottal variation, the vocal tract response, and the frequency scale, respectively. Computing them one by one is not as efficient as computing them together, so this article introduces a new speech feature extraction approach. The article is introductory; it focuses on the basic concepts of our new approach and does not elaborate on all applications. It demonstrates that the unit of a cepstral value, which is a spectral value of spectrums, is a unit of acceleration since its discrete variable, the quefrency, can be expressed in Hertz-per-microsecond. The article shows how to produce refined voice analysis from robust estimates and how to reconstruct speech signals from feature spaces. And it concludes that the pitch track of the new approach is as good as two open-source pitch extractors. Combining multiple processes, attenuating background noises, and enabling distant-speech recognition, we introduce the Speech Quefrency Transform (SQT) approach as well as multiple quefrency scales. SQT is a set of frequency transforms whose spectral leakages are controlled per a frequency-modulation model. SQT captures the stationarity of time series onto a hyperspace that resembles the cepstrogram when it is reduced for pitch track extraction.
Psychometric properties of Persian version of Depression Literacy (D-Lit) questionnaire among general population
Authors: Tehrani Hadi , Nejatian Mahbobeh , Moshki Mahdi , Jafari Alireza
Published: July 2022

Background
The prevalence of depression in society is increasing and there is a need for a suitable tool to assess the health literacy of people in this field. This study was conducted to evaluate the psychometric of the Iranian version of the depression literacy (D-Lit) questionnaire.
Methods
This cross-sectional study was conducted on 845 participants with a proportional stratified sampling method. First, the translation and cultural adaptation of questionnaire was performed. Then, the validity of D-Lit was assessed by face validity, content validity, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA). The reliability of D-Lit was assessed by the Cronbach’s alpha coefficient and McDonald omega coefficient.
Results
Based on the results of EFA, 5 factors emerged with eigenvalues of greater than 1, which accounted for 56.30% of the variance. Based on the results of CFA, one question was deleted and the results of goodness fit indexes confirmed the model. Cronbach’s alpha coefficient and McDonald omega coefficient for D-Lit questionnaire were 0.890 and 0.891, respectively. Finally, D-Lit questionnaire with 21 questions and 5 subscales of Knowledge of the psychological symptoms (5 items), Knowledge about the effectiveness of available treatment methods (4 items), Knowledge about cognitive-behavioral symptoms (6 items), Knowledge about taking medications and their side effects (4 items), and Knowledge of the severity of the disease (2 items) were confirmed.
Conclusion
The results of this psychometric evaluation confirmed the Persian version of D-Lit questionnaire with 21 questions and 5 subscales is an appropriate tool for measuring people's literacy about depression.
Corporate social responsibility—A swap like role between a firm and its social stakeholders
Authors: Liu Mei , Ma Qing-Ping
Published: July 2022

We propose that 1) social stakeholders’ feelings of fairness and justice need to be satisfied, and they control social resources which firms need for profitable business operations; and 2) corporate social responsibility (CSR) practices from firms represent a swap-like tool in risk management to obtain stable supply of social resources from social stakeholders. To test these proposals, we use a sample of 20,275 deals by 2,488 firms from 48 home countries investing into 121 host countries. We find that high CSR performance significantly attenuates increases in shareholder value following foreign direct investment (FDI) announcements that cause positive abnormal returns, and significantly mitigates decreases in shareholder value following FDI announcements that cause negative abnormal returns. These results support our proposal that CSR acts like a swap.JEL Classification: F21, F23, M14, G14, G32.
Mutagenic and/or carcinogenic compounds in meat and meat products: Heterocyclic aromatic amines perspective
Authors: Oz E. , Oz F.
Published: July 2022

Meat and meat products, which have a very important place in terms of nutrition, can endanger human health if they are not properly prepared and preserved. Meat and meat products except for products such as sushi, which are deliberately consumed raw, are generally consumed immediately after cooking. Cooking done properly gives meat and meat products their unique taste and aroma, increases their digestibility and makes them microbiologically safe. However, some harmful food toxicants can occur during the cooking process. Heterocyclic aromatic amines can be formed during cooking of the proteinaceous foods such as meat and meat products. Epidemiological studies have proved that heterocyclic aromatic amines are mutagenic and/or carcinogenic compounds. Therefore, having sufficient knowledge about heterocyclic aromatic amines will help to reduce the health risk posed by these com  pounds. In this context, in the present study, basic information about heterocyclic aromatic amines that can be formed during the heat treatment of meat and meat products was reviewed.
Raman spectroscopic techniques for meat analysis: A review
Authors: Pchelkina V. A. , Chernukha I. M. , Fedulova L. V. , Ilyin N. A.
Published: July 2022

Raman spectroscopy (vibrational spectroscopy) proved to be an effective analytical approach in the field of geology, semiconductors, materials and polymers. Over the past decade, Raman spectroscopy has attracted the attention of researchers as a non-destructive, highly sensitive, fast and eco-friendly method and has demonstrated the unique capabilities of food analysis. The use of Raman spectroscopic methods (RSMs) to assess the quality of meat and finished products is rapidly expanding. From the analysis of one sample, you can get a large amount of information about the structure of proteins, the composition of fatty acids, organoleptic parameters, autolysis and spoilage indicators, authentication of raw materials, technological properties. An important advantage of the method is the comparability of the results obtained with the data of traditional analytical methods. Traditional methods of determining the quality of meat are often time-consuming, expensive and lead to irreversible damage to a sample. It is difficult to use them in production conditions directly on the meat processing lines. Technological advances have made it possible to develop portable Raman spectroscopes to use directly in production. The article presents the basic principles of Raman spectroscopy, system  atizes the results of the use of RSMs for the analysis of meat quality from different types of slaughter animals and provides tools for analyzing the data of the obtained spectra. Raman spectra have many dependent variables, so chemometric assays are used to work with them. Literature analysis has shown that currently there is no unified database of meat spectra in the world, standardized protocols for conducting research and processing the obtained results. In Russia, the use of RSMs is a new,
Al-Ta'āzur bayna Taʿlīm Mahārat al-Qirā'ah ladá Ṭullāb Madrasah Bayt al-Hudá al-Ibtidā'īyah wa-Taʿlīm Qirā'ah wa-Kitābah al-Qur'ān al-Karīm
Authors: Zuhrudin Achmad , Muna Erlita Zulfa Nailal
Published: July 2022

One of Baitul Huda Madrasah Ibtidaiyah (elementary school) missions was to instill the habit of Qur'an reading. Thus, daily Qur'an reading activities were implemented in the school. Students who have not been able to read the Qur'an or are older than 12 years old must join the Qur'an reading - writing (BTQ) activity which uses Yanbua method. The purpose of this research is to characterize fifth-grade students' Arabic reading abilities acquired in conjunction with BTQ activities at Baitul Huda elementary school. It was expected that students who followed Yanbua method would improve their Arabic reading abilities, especially reading aloud skill. This research shows that Baitul Huda elementary school employed online and face-to-face Arabic learning methods since the COVID-19 epidemic. In addition, while the fifth graders have an excellent Arabic reading capacity, a few students read Arabic texts with a bit of stutter. Finally, the results of reading skills tests that correlate with BTQ learning indicated that 89.2 percent of students passed and 10.8 percent did not meet the minimal score, indicating that the proportion of BTQ learning positively affects students' Arabic reading ability.
Approaches of Attack Surface Estimation and Web Browser Fuzzing
Authors:   The Academy of the Federal Guard Service of the Russian Federation, Kozachok Alexander , Nikolaev Dmitry ,   The Academy of the Federal Guard Service of the Russian Federation, Erokhina Natalya ,   The Academy of the Federal Guard Service of the Russian Federation
Published: July 2022

Abstract Purpose of the work is to develop of an approach to determining the attack surface based on the analysis of the difference in code coverage and its application to the analysis of web browsers. Research method is to use an instrumentation compiler to analyze code coverage depending on the input data. The proposed approach makes it possible to evaluate the relationship between the input data processed by the analyzed application and the program code by calculating the coverage difference and excluding from the analysis the modules called regardless of the input data. Results of the research: the existing general approaches to software fuzzing, and the features of approaches to fuzzing web browsers, are considered. In general, software fuzzing is performed using one of three methods: blackbox, gray-box, and white-box. The basic criterion for distinguishing these methods is the completeness of information about the source code of the software under test. Web browser fuzzing can be divided into static and dynamic. Approaches to fuzzing complex software can be divided into two groups: analysis of a monolithic application, fuzzing of individual application modules (library interfaces). The difference between these groups is determined by the completeness of the involvement of the functional components of the software under study in the testing process. Each of the levels has its own advantages and disadvantages. Often these shortcomings can be compensated by a combination of fuzzing different fuzzing targets. To correctly determine fuzzing targets, it is necessary to identify the attack surface of the software under study. The authors proposed an approach to assessing the attack surface by calculating the coverage difference; it allows excluding from the analysis modules that are called regardless of the input data. Scientific and practical significance: the results of the article consist in the development of a new approach to determining the attack surface based on the analysis of the difference in coverage of the code of the analyzed application, depending on the data supplied to the input, and allowing to exclude modules from the analysis that are called regardless of the input data.
Mulheres e Suas Percepções Sobre as Suas Experiências no Parto: Violência ou Cuidado?
Authors: Brito Hellen Assompção de , Silva Thiago Augusto Soares Monteiro da , Gomes Elisângela do Nascimento Fernandes , Godinho Jannaina Sther Leite , Souza Alessandra da Silva , Silva Geisa Sereno Velloso da
Published: July 2022

O presente estudo tem como objetivos: Analisar a assistência prestada as mulheres no período parturitivo; identificar o tipo de assistência prestada a mulher no período parturitivo. Avaliar o grau de conhecimento das mulheres acerca da violência obstétrica e seus direitos no período parturitivo. Trata-se de um descritivo qualitativo foi realizado em um setor de ginecologia e obstetrícia de um hospital universitário. Utilizou-se um instrumento, composto por perguntas abertas e fechadas enviadas através do formulário do Google Forms. As participantes da pesquisa foram mulheres com idade de 21 a 49 anos que já vivenciaram o gestar e o partejar. Os dados coletados foram organizados e procedeu-se a análise de conteúdo. Foram entrevistadas 12 mulheres, sendo 42% com idade entre 40-49 anos, 50% casadas, 57% se autodeclaram brancas e 50% com ensino superior completo. 75% referem ter conhecimento da temática, porém após análise dos relatos a maioria delas reportaram episódios de violência, tais como: episiotomia não consentida, manobra de kristeller, violência verbal por parte dos profissionais, entre outros. Assim, concui-se que apesar de relatarem serem possuidoras de conhecimento 74% delas foram sim vítimas de um ou mais tipos de violência. Identifica-se a necessidade de mais estudos sobre a temática.
Palavras-Chave: Violência Obstétrica; Violência; Trabalho de Parto.
universo das universitárias versus conhecimento sobre o contraceptivo oral: Uma reflexão para a enfermagem.
Authors: Groetares Rebecah Ariela , Silva Thiago Augusto Soares Monteiro da , Gomes Elisângela do Nascimento Fernandes , Souza Alessandra da Silva , Silva Jannaína Sther Leite Godinho da , Silva Geísa Sereno Veloso da
Published: July 2022

O contraceptivo hormonal oral é um dos métodos mais utilizados atualmente. Entretanto, ainda existem dúvidas por parte das usuárias quanto aos efeitos adversos, contraindicações e atitudes a serem tomadas durante a utilização das pílulas. Desta forma surge a inquietação se estas dúvidas também são frequentes em universitárias. Objetivo: Avaliar o conhecimento das universitárias quanto às atitudes a serem tomadas na quebra de rotina durante o uso do contraceptivo oral; Discutir qual a atuação da enfermagem na vivencia das participantes durante o processo de escolha do contraceptivo e orientações. Método: Trata-se de uma pesquisa quanti-qualitativa de cunho descritivo exploratório, constituído por um questionário com universitárias mulheres, maiores de dezoito anos e em idade fértil. O trabalho foi submetido ao Comitê de ética e Pesquisa da Universidade de Vassouras, sendo o mesmo aprovado com o parecer nº4.743.606. Os dados foram tabulados em uma planilha do Excel e foi procedida análise estatística descritiva. Resultados: Apesar de 68% das mulheres entrevistadas afirmarem saber quais atitudes tomar quando houver falha no uso do método, mostraram comportamento equivocado, diminuindo a eficacia do contraceptivo. Conclusão: O estudo mostrou-se relevante ao constatar a falta de conhecimento das universitárias, havendo a necessidade de traçar estratégias que enfatizem a maneira correta de utilizar o contraceptivo hormonal oral.
Palavras-Chave: Assistência de Enfermagem; Anticoncepcionais Orais; Orientação.
impactos da trajetória acadêmica na saúde mental dos graduandos
Authors: Nunes Luana Ferreira de Oliveira Marques , Silva Thiago Augusto Soares Monteiro da , Silva Eliara Adelino da , Souza Alessandra da Silva , Ricci Adiel Queiroz , Alves Manoela
Published: July 2022

A trajetória acadêmica é marcada por alterações pessoais e profissionais. Dentre elas, pode-se observar impactos que corroboram para que consequências à saúde mental dos acadêmicos sejam desenvolvidas. Assim, o presente estudo tem como objetivo identificar os efeitos que a vida acadêmica pode provocar na saúde mental do graduando. A pesquisa trata-se de uma revisão de literatura narrativa e utilizou como base de dados as plataformas Scielo (Scientific Eletronic Library Online), LILACS (Literatura Latino-Americana e do Caribe em Ciências em Saúde), MEDLINE, Google Acadêmico e Revista Pró-UniverSus, através do critério de inclusão e exclusão, resultando em 16 artigos selecionados e 325 excluídos. Os resultados demonstraram que a graduação traz impactos mentais devido à transição da infância para a vida adulta, pelas responsabilidades e cobranças que são geradas diariamente no ensino superior e na nova rotina, o que ocasiona um desequilíbrio psicológico ao estudante e propicia o desenvolvimento de transtornos mentais ou psicossomáticos. Conclui-se que as instituições de ensino podem atuar como fatores estressores que provocam o desequilíbrio psíquico; em contrapartida, podem também proporcionar meios a partir dos quais o equilíbrio mental, social e físico seja reestabelecido.  
Palavras-chave: Saúde Mental; Vida Acadêmica; Transtornos Mentais.
dificuldades no cotidiano da família e da enfermagem para o combate da obesidade infantil
Authors: Ribeiro Priscila Aparecida de Souza , Souza Alessandra da Silva , Godinho Jannaina Sther Leite Godinho , Silva Geisa Sereno Velloso da , Gomes Elisangela do Nascimento Fernandes , Silva Eliara Adelino da
Published: July 2022

Este estudo tem como objetivo identificar as dificuldades do cotidiano familiar na obesidade infantil e as ações desenvolvidas pelos enfermeiros na atenção primária com a família de crianças com obesidade infantil. Metodologia: Trata-se de uma revisão bibliográfica de cunho qualitativo. Para elaboração deste estudo, os artigos foram consultados na Biblioteca Virtual de Saúde (BVS), através da base de dados LILACS e BDENF, utilizando os seguintes descritores: enfermagem AND família AND obesidade infantil AND. Na base LILACS foram encontrados 8 artigos, mas serão utilizados apenas 4 que atendem o critério de inclusão. Na base dados da BDENF foram encontrados 49 artigos, contudo, após a aplicação dos critérios de inclusão foram separados 3 artigos, mais utilizado apenas 1 artigo devido os outros 2 serem equivalentes do LILACS e como critérios de exclusão, os textos incompletos e em língua estrangeira, textos que não abordassem a temática estabelecida e com recorte temporal inferior a 2017. Resultados: As dificuldades do cotidiano familiar na obesidade infantil e ações desenvolvidas pelos enfermeiros na atenção primária com a família de crianças com obesidade infantil. Conclusão: O estudo buscou relatar os índices de aumento da obesidade infantil e todas as estratégias que devem ser tomadas, a fim de que todos os envolvidos no processo estejam aptos e preparados para o tratamento.
Palavras-Chave: Enfermagem; Família; Obesidade Infantil.
Contribuições da liderança coaching para enfermeiros: um estudo reflexivo
Authors: Ribeiro Wanderson Alves , Santos Larissa Christiny Amorim dos , Medeiros Uesclei Pinto de , Alves Ana Lúcia Naves , Neves Keila do Carmo , Fassarella Bruna Porath Azevedo , Filho Fernando Salgado
Published: July 2022

A liderança é reconhecida como competência gerencial imprescindível ao trabalho de diversos profissionais, entre eles o enfermeiro. Dentre os inúmeros modelos de liderança, cabe destacar a Liderança Coaching, baseada no processo coaching, que compreende um novo direcionamento das organizações de saúde, inovador entre enfermeiros. Com base no exposto, o artigo tem como objetivo refletir sobre as contribuições da liderança Coaching para enfermeiros no âmbito assistencial. Trata-se de um estudo descritivo, qualitativo do tipo análise reflexiva, elaborado a partir de revisão da literatura. A revisão foi realizada de forma não sistemática, com busca aleatória do material nas bases de dados da biblioteca virtual de saúde e no Google Acadêmico. Assim, foram identificadas 28 publicações com potencial para fundamentar este manuscrito. Após a avaliação dos títulos e resumos, 13 artigos foram considerados para leitura na íntegra e, contemplando os critérios de inclusão, puderam subsidiar a esta reflexão. No contexto da enfermagem, os estudos trazem consigo uma metodologia inovadora que propõe uma avaliação correlacional da percepção da liderança entre líderes e liderados. Conclui-se que foi possível refletir e conhecer mais sobre coaching, bem como sua inserção na enfermagem. A prática de coaching é recente e se mostra essencial para o desenvolvimento da habilidade de liderar. A técnica de coaching auxilia no intuito de aperfeiçoar a atuação profissional do enfermeiro aliado ao processo de desenvolvimento da pessoa e de sua vida pessoal.
Palavras-chave: Enfermeiras e Enfermeiros; Coaching; Liderança.