bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Vitamin D Metabolism in Patients with Type 1 Diabetes Mellitus in the Setting of Cholecalciferol Treatment
Authors: Povaliaeva Alexandra , Pigarova Ekaterina , Zhukov Artem , Bogdanov Viktor , Dzeranova Larisa , Mel’nikova Olga , Pekareva Elena , Malysheva Natalya , Ioutsi Vitaliy , Nikankina Larisa , Rozhinskaya Liudmila
Published: December 2020

In this prospective controlled study, we examined 25 adults with adequately controlled (HbA1c level < 8.0%) type 1 diabetes mellitus (T1DM) and 49 conditionally healthy adults, intending to reveal the diversity of vitamin D metabolism in the setting of cholecalciferol intake at a therapeutic dose. All patients received a single dose (150,000 IU) of cholecalciferol aqueous solution orally. Laboratory assessments including serum vitamin D metabolites (25(OH)D3, 25(OH)D2, 1,25(OH)2D3, 3-epi-25(OH)D3 and 24,25(OH)2D3), free 25(OH)D, vitamin D-binding protein (DBP) and parathyroid hormone (PTH) as well as serum and urine biochemical parameters were performed before the intake and on Days 1, 3 and 7 after the administration. The studied groups had no significant differences in baseline parameters except that the patients with diabetes showed higher baseline levels of free 25(OH)D (p < 0.05). They also lacked a correlation between the measured and calculated free 25(OH)D in contrast to the patients from the control group (r = 0.41, p > 0.05 vs. r = 0.88, p < 0.05), possibly due to the glycosylation of binding proteins, which affects the affinity constant for 25(OH)D. The elevation of vitamin D levels after the administration of cholecalciferol was comparable in both groups, with slightly higher 25(OH)D3 levels observed in the diabetes group throughout the study since Day 1 (p < 0.05). Overall, our data indicate that in patients with adequately controlled T1DM 25(OH)D3 levels and the therapeutic response to cholecalciferol is similar to that in healthy individuals.
Vitamin D Supplementation Improves the Effects of the Rehabilitation Program on Balance and Pressure Distribution in Patients after Anterior Cervical Interbody Fusion-Randomized Control Trial
Authors: Skrobot Wojciech , Perzanowska Ewelina , Krasowska Katarzyna , Flis Damian J. , Dzik Katarzyna P. , Kloc Wojciech , Kaczor Jan Jacek , Antosiewicz Jędrzej
Published: December 2020

Study Design: A double-blinded, randomized controlled trial. Background: Surgery is effective in reducing pain intensity in patients with cervical disc disease. However, functional measurements demonstrated that the results have been not satisfactory enough. Thus, rehabilitation programs combined with the supplementation of vitamin D could play an essential role. Methods. The study recruited 30 patients, aged 20 to 70 years, selected for anterior cervical interbody fusion (ACIF). The patients were randomly divided into the placebo (Pl) and vitamin D (3200 IU D3/day) supplemented groups. The functional tests limits of stability (LOS), risk of falls (RFT), postural stability (PST), Romberg test, and foot pressure distribution were performed before supplementation (BS—week 0), five weeks after supplementation (AS—week 5), four weeks after surgery (BSVR—week 9), and 10 weeks after supervising rehabilitation (ASVR—week 19). Results. The concentration of 25(OH)D3 in the serum, after five weeks of supplementation, was significantly increased, while the Pl group maintained the same. The RFT was significantly reduced after five weeks of vitamin D supplementation. Moreover, a further significant decrease was observed following rehabilitation. In the Pl group, no changes in the RFT were observed. The overall postural stability index (OSI), LOS, and the outcomes of the Romberg test significantly improved in both groups; however, the effects on the OSI were more pronounced in the D3 group at the end of the rehabilitation program. Conclusions. Our data suggest that vitamin D supplementation positively affected the rehabilitation program in patients implemented four weeks after ACIF by reducing the risk of falls and improving postural stability.
The Emerging Therapeutic Landscape of ALK Inhibitors in Non-Small Cell Lung Cancer
Authors: Gristina Valerio , La Mantia Maria , Iacono Federica , Galvano Antonio , Russo Antonio , Bazan Viviana
Published: December 2020

The treatment of metastatic non-small cell lung cancer (NSCLC) has undergone a paradigm shift over the last decade. Better molecular characterization of the disease has led to the rapid improvement of personalized medicine and the prompt delivery of targeted therapies to patients with NSCLC. The discovery of the EML4-ALK fusion gene in a limited subset of patients affected by NSCLC and the subsequent clinical development of crizotinib in 2011 has been an impressive milestone in lung cancer research. Unfortunately, acquired resistances regularly develop, hence disease progression occurs. Afterward, modern tyrosine kinase inhibitors (TKIs), such as ceritinib, alectinib, brigatinib, and lorlatinib, have been approved by the Food and Drug Administration (FDA) for the management of anaplastic lymphoma kinase (ALK)-positive NSCLCs. Several compounds are currently under investigation to achieve the optimal strategy of therapy. Additionally, the results of ongoing clinical trials with novel-generation TKI will provide more evidence on the best sequence in the treatment of ALK-positive NSCLC patients. In this review, we provide a comprehensive overview of the state-of-the-art targeted therapy options in ALK-positive NSCLCs. Resistance, potential therapeutic strategies to overcome drug resistance, and future perspectives for this subset of patients are critically analyzed and summarized.
The Role of Participation in the Responsible Innovation Framework for Biofuels Projects: Can It Be Assessed?
Authors: Marques Postal Andreia , Benatti Gabriela , Palmeros Parada Mar , Asveld Lotte , Osseweijer Patrícia , Da Silveira José
Published: December 2020

The growth in biofuels’ investment brings with it concerns about the social and environmental impacts of the sector. Several tools and frameworks have been used to address these concerns, including the Responsible Research and Innovation (RRI) framework. This paper analyzes whether this framework can be applied in contexts where local culture and values shape differently the freedom of speech and engagement, such as in developing countries in which biofuel innovation projects are often implemented. A literature review focused on eight case studies of other authors was used to explore the role of “participation” as a structural element of the RRI framework and the impact of its absence where effective participation in the innovation development process is not possible. In conclusion, we highlight how this inspirational normative framework, designed to influence innovation, is misused to judge its impacts. More than that, the conclusions of such misused applications reflect more the difficulties involved in applying guidelines than the responsible character of the innovation, whose impacts are usually defined upfront materially and measurably.
Extending the Fully Bayesian Unfolding with Regularization Using a Combined Sampling Method
Authors: Baroň Petr , Kvita Jiří
Published: December 2020

Regularization extensions to the Fully Bayesian Unfolding are implemented and studied with an algorithm of combined sampling to find, in a reasonable computational time, an optimal value of the regularization strength parameter in order to obtain an unfolded result of a desired property, like smoothness. Three regularization conditions using the curvature, entropy and derivatives are applied, as a model example, to several simulated spectra of top-pair quark pairs that are produced in high energy pp collisions. The existence of a minimum of a χ2 between the unfolded and particle-level spectra is discussed, with recommendations on the checks and validity of the usage of the regularization feature in Fully Bayesian Unfolding (FBU).
An Evaluation of Symmetries in Ground Reaction Forces during Self-Paced Single- and Dual-Task Treadmill Walking in the Able-Bodied Men
Authors: Al-Juaid Rawan , Al-Amri Mohammad
Published: December 2020

Gait is a complex autonomous activity that has long been viewed as a symmetrical locomotion, even when it adapts to secondary concurrent attention-demanding tasks. This study aimed to evaluate the symmetry of the three ground reaction forces (GRFs) in able-bodied individuals during self-paced treadmill walking with and without concurrent cognitive demands. Twenty-five male participants (age: 34.00 ± 4.44 years) completed two gait assessment sessions, each of whom were familiarized with the walking trials during their first session. Both sessions involved six-minute self-paced treadmill walking under three conditions: single-task walking and walking while concurrently responding to auditory 1-back and 2-back memory tasks. The symmetry of the GRFs was estimated using a nonlinear approach. Changes in the symmetry and walking speed across conditions in both sessions were assessed using inferential statistics. Results demonstrated that the three GRFs deviated from perfect symmetry by ≥10%. Engaging working memory during walking significantly reduced the symmetry of the vertical GRF (p = 0.003), and its detrimental effects on walking speed were significantly reduced in the second session with respect to the first session (p < 0.05). The findings indicate imperfect gait symmetry in able-bodied individuals, suggesting that common perceptions of gait symmetry should be reconsidered to reflect its objective importance in clinical settings.
The Study for Longitudinal Deformation of Adjacent Shield Tunnel Due to Foundation Pit Excavation with Consideration of the Retaining Structure Deformation
Authors: Zhang Xinhai , Wei Gang , Jiang Chengwu
Published: December 2020

By selecting the ratio of the cumulative maximum deformation of the retaining structure to the excavation depth as the control parameter of the retaining structure deformation, this paper established a sidewall unloading model which can consider the deformation of the retaining structure and the spatial effect of foundation pit excavation. Meanwhile, the impact region of the sidewall was divided to calculate the distribution of additional stress caused by foundation pit excavation. On this basis, through introducing the collaborative deformation model for rotation and dislocation of a shield tunnel, this paper studied the longitudinal deformation of the adjacent shield tunnel due to foundation pit excavation. Moreover, several engineering cases were given to verify the reliability of the proposed method, and the influencing factors were analyzed. The following conclusions were obtained: the axial horizontal displacement of the shield tunnel by the side of the foundation pit was normally distributed, and the calculated value was in good agreement with the measured value; the longitudinal deformation of the shield tunnel was mainly induced by the unloading effect of the sidewall of the foundation pit, which was parallel and closed to the tunnel; the soil excavation in the vicinity of the buried depth of the tunnel would result in a significant increase in longitudinal deformation; with the increase in the retaining structure deformation of the foundation pit, the longitudinal deformation of the adjacent shield tunnel and its influence scope also increased; the longitudinal deformation of the shield tunnel decreased with the increase of clearances between the foundation pit and tunnel; and finally, the excavation of the foundation pit had a great influence on the shallowly buried shield tunnel nearby, and the effect of foundation pit excavation on the tunnel decreased with the increase of the burial depth of the shield tunnel.
Botulinum Toxin in the Treatment of Headache
Authors: Becker Werner J.
Published: December 2020

Botulinum toxin type A has been used in the treatment of chronic migraine for over a decade and has become established as a well-tolerated option for the preventive therapy of chronic migraine. Ongoing research is gradually shedding light on its mechanism of action in migraine prevention. Given that its mechanism of action is quite different from that of the new monoclonal antibodies directed against calcitonin gene-related peptide (CGRP) or its receptor, it is unlikely to be displaced to any major extent by them. Both will likely remain as important tools for patients with chronic migraine and the clinicians assisting them. New types of botulinum toxin selective for sensory pain neurons may well be discovered or produced by recombinant DNA techniques in the coming decade, and this may greatly enhance its therapeutic usefulness. This review summarizes the evolution of botulinum toxin use in headache management over the past several decades and its role in the preventive treatment of chronic migraine and other headache disorders.
Dynamical Stability and Geometrical Diagnostic of the Power Law K-Essence Dark Energy Model with Interaction
Authors: Chen Bo-Hai , Wu Ya-Bo , Xu Dong-Fang , Dong Wei , Zhang Nan
Published: December 2020

We investigate the cosmological evolution of the power law k-essence dark energy (DE) model with interaction in FRWL spacetime with the Lagrangian that contains a kinetic function F(X)=−X+X. Concretely, the cosmological evolution in this model are discussed by the autonomous dynamical system and its critical points, together with the corresponding cosmological quantities, such as Ωϕ, wϕ, cs2, and q, are calculated at each critical point. The evolutionary trajectories are drawn in order to show the dynamical process on the phases plan around the critical points. The result that we obtained indicates that there are four dynamical attractors, and all of them correspond to an accelerating expansion of universe for certain potential parameter and coupling parameter. Besides that, the geometrical diagnostic by the statefinder hierarchy S3(1) and S4(1) of this scalar field model are numerically obtained by the phase components, as an extended null diagnostic for the cosmological constant. This diagnostic shows that both the potential parameter λ and interaction parameter α play important roles in the evolution of the statefinder hierarchy.
Pengaruh Zakat, Pembiayaan Syariah Dan APBN Terhadap Pengentasan Kemiskinan Di Indonesia Dan Malaysia
Authors: Ridlo Musalim , Muthohar Ahmad Mifdlol
Published: December 2020

Tujuan penelitian ini adalah untuk menganalisis pengaruh Anggaran Pendapatan dan Belanja Negara (APBN), Pembiayaan syariah dan Zakat terhadap pengentasan Kemiskinan. Metode pengumpulan data dilakukan dengan menggunakan data sekunder yang didapatkan dari website resmi seperti www.kemenkeu.go.id, www.baznas.go.id, www.zakat.com. Kemudian data yang didapat berupa data panel di uji menggunakan regresi linear berganda melalui aplikasi statistik E-VIEWS 9 dengan mengestimasi semua variabel independen terhadap variabel dependen. Hasil penelitian menunjukkan bahwa APBN berpengaruh positif dan tidak signifikan terhadap kemiskinan, pembiayaan syariah berpengaruh negatif dan tidak signifikan dan zakat berpengaruh negatif dan signifikan terhadap kemiskinan.
Smart Microneedles for Therapy and Diagnosis
Authors: Zhang Xiaoxuan , Wang Yuetong , Chi Junjie , Zhao Yuanjin
Published: December 2020

Microneedles represent a cutting-edge and idea-inspiring technology in biomedical engineering, which have attracted increasing attention of scientific researchers and medical staffs. Over the past decades, numerous great achievements have been made. The fabrication process of microneedles has been simplified and becomes more precise, easy-to-operate, and reusable. Besides, microneedles with various features have been developed and the microneedle materials have greatly expanded. In recent years, efforts have been focused on generating smart microneedles by endowing them with intriguing functions such as adhesion ability, responsiveness, and controllable drug release. Such improvements enable the microneedles to take an important step in practical applications including household drug delivery devices, wearable biosensors, biomedical assays, cell culture, and microfluidic chip analysis. In this review, the fabrication strategies, distinctive properties, and typical applications of the smart microneedles are discussed. Recent accomplishments, remaining challenges, and future prospects are also presented.
Melhoria na eficiência energética de um armazém frigorificado através do método PDCA
Authors: Brombal Anselmo Eduardo Leme , Cansi Flaviano , Bodot Luiz Olivar Costa , Alves Rodrigo Ramos , De Lima Miguelangelo Geimba
Published: December 2020

As empresas modernas buscam o tempo todo formas eficazes de se destacar no mercado competitivo. Dessa forma, tornou-se cada vez mais importante conhecer e fazer uso das ferramentas administrativas existentes, na busca de inovação e consolidação de seus métodos para a melhoria da produtividade. O presente trabalho utilizou o método PDCA para implantar melhorias no processo de produção em de um armazém frigorífico localizado em Nova Santa Rita no Rio Grande do Sul. O tema escolhido foi relacionado a eficiência energética, um dos principais custos hoje de uma empresa deste segmento devido a necessidade em manter as câmaras deste armazém refrigeradas. Os resultados obtidos mostraram que o Ciclo PDCA pode trazer benefícios relevantes nos processos produtivos, e que, caso ocorra alguma adversidade em uma das etapas, pode-se recorrer ao uso de ferramentas complementares para garantir sua total eficácia. Concluiu-se que a gestão de todo o processo deve ser feita levando em consideração o que se tem de concreto, analisando cada etapa em suas estatísticas reais e não apenas teóricas.
Belediyelere Ait Değerli Alanların Zaman İçerisinde Gayrimenkul Odaklı Büyümeye Maruz Bırakılması Üzerine Ampirik Bir Araştırma
Authors: GÜVEN Ahmet
Published: December 2020

1980 sonrası dönemde, büyükşehirlerde hızla yaygınlaşan, ilerleyen yıllarda Anadolu’daki diğer belediyelerde de görülen gayrimenkul sektörünün hızla büyümesi başta kent merkezlerinde yeni alan talebi yaratırken, kentin çevresinde yer alan değerli alanların da zamanla kentin içine çekilmesine sebep olmuştur. Bu etki başta tarım alanlarında üretim yapan kişilerin tarımsal üretimden vazgeçmelerine, daha sonra ellerindeki arazileri arsaya çevirerek bir rant aracı haline getiren küçük bir gurubun doğmasına neden olmuştur. Bu guruplar bununla da yetinmemişler, tarıma dayalı sanayi bölgelerine göz dikerek bu alanların da imara açılması yönünde girişimlerde bulunmuşlardır. Bölgenin tarıma dayalı sanayisi ve tarım sektörü üzerinde ciddi sorunlar ortaya çıkaran bu gelişmeler, kent ekonomisinin bozulması yanında en büyük etkiyi hiç kuşkusuz o bölgede yaşayan insanlar üzerinde ortaya çıkarmıştır. Bu bölgelerde yaşayan insanlar üzerinde, tarıma dayalı faaliyet alanlarının daralması, mevcut yerleşim alanlarının arsaya dönüşerek imara açılması, başta işsizlik olmak üzere, göç, konut fiyatlarının ve kiralarının aşırı artışı, yeşil alanların hızla azalması ve tarımsal üretimin azalması gibi pek çok soruna neden olmuştur. Tokat ili özelinde düşünüldüğünde kendine ve bölgesine tarımsal açıdan yeten sayılı iller arasında yer almasına rağmen günümüzde elverişli tarım alanlarının hızla tüketildiği, tarım ve sanayi yerine konuta dayalı bir ekonomik kalkınma politikasının kente hakim olduğu görülmektedir. Özellikle Tokat Karşıya Bağlarının olduğu bölgenin 20-30 yıl içinde geçirdiği değişimin beraberinde getirdiği ekonomik, sosyal ve çevresel birçok problemin arkasında bu yatmaktadır. Bu sorular kapsamında ele alınan çalışmada öncelikle kavramsal açıdan sorunun kaynağı olan gayrimenkul odaklı büyüme ve küçük ölçekli kentlerde bu büyümenin kent ve çevre üzerine etkisine değinilecektir. Ardından bu bölgede gerçekleştirilecek bir alan araştırmasıyla sorunun kaynakları ve bölgede yaşayan insanların düşünceleri gerçekleştirilen mülakatlarla tespit edilerek analiz edilecektir.
Fortalezas e inminencias en la central de esterilización: Percepción de las enfermeras
Authors: Barreda Ayasta Lucia de Fatima , Bazán Sánchez Asunción Carmen Luz , Díaz Manchay Rosa Jeuna , Zapata Rueda Aurora Violeta , Olivos Pérez Margot
Published: December 2020

Introducción: Las enfermeras de central de esterilización, aunque no brindan un cuidado directo al paciente son las responsables de garantizar calidad en los procesos, la seguridad del paciente y la prevención de riesgos. Objetivo:  Describir la percepción que tienen las enfermeras sobre sus fortalezas e inminencias al trabajar en la central de esterilización del Hospital Regional Lambayeque, Perú. Método: Estudio cualitativo descriptivo, la muestra fueron 12 enfermeras, se usó la entrevista semiestructurada y el análisis de contenido temático. Resultados principales: Fortalezas que garantizan la seguridad del paciente: Capacitación continua, trabajo en equipo y sistema de trazabilidad; Inminencias para la prevención de riesgo: Mantenimiento preventivo, abastecimiento de recursos y salud ocupacional. Conclusión general: A pesar de las fortalezas personales e institucionales, las enfermeras reconocen la necesidad de implementar un sistema de prevención de riesgos laborales, efectivizar un mantenimiento preventivo a equipos; pues se realiza solo un mantenimiento correctivo cuando ya ocurre el problema.
Daño moral por intromisión ilegítima en el derecho al honor como consecuencia de la inclusión indebida en registros de morosos
Authors: ESPÍN ALBA Isabel
Published: December 2020

La inclusión de los datos de un deudor en los ficheros de información de solvencia patrimonial y crédito, también denominados registros de morosos, puede ocasionar un impacto extremadamente negativo en su reputación personal y profesional. En los últimos años, el Tribunal Supremo español pudo construir una doctrina sobre la indemnización por daños causados por intromisión ilegítima en el derecho al honor por inclusión indebida en registros de morosos. El objeto del presente artículo es estudiar esa doctrina jurisprudencial, destacando el problema del valor simbólico de las indemnizaciones planteadas, pues este tipo de cuantificación es disuasoria para los afectados por la inclusión indebida. En ese sentido, se analiza la función del derecho de daños en estos supuestos, avanzando alguna reflexión sobre el valor preventivo de ciertos mecanismos del Reglamento Europeo de Protección de Datos, en aras del fortalecimiento de una cultura jurídica de la prevención.
La procedencia en México de la responsabilidad civil por el incumplimiento de deberes entre cónyuges
Authors: Rodríguez Stephen Javier Urbina , Zapata Denis María Minerva
Published: December 2020

Del matrimonio derivan deberes que asumen ambos esposos al momento de contraerlo, como la fidelidad y ayuda mutua. En México, según se analiza en este estudio a través de la doctrina, normas vigentes y criterios jurisdiccionales existentes en la materia, sí procede la reparación que genera su incumplimiento pero no es reclamada ante los tribunales al mantenerse la concepción tradicional de que su inobservancia solo da lugar a sanciones como la disolución del vínculo, desconociéndose que es legalmente posible exigir una indemnización conforme a las reglas de la responsabilidad civil en general, trascendiendo la esfera moral y religiosa, para introducirse al ámbito jurídico. Así, en este estudio se pretende sentar las bases al reconocimiento en nuestro país de la procedencia de la reparación del daño causado por el incumplimiento de dichos deberes conyugales.
Parámetros de protección del Sistema Interamericano de Derechos Humanos a la movilidad humana
Authors: MARTINEZ LAZCANO Alfonso Jaime
Published: December 2020

En este artículo se analizaron diversos criterios emitidos por la Corte Interamericana de Derechos Humanos que versan sobre la migración, de manera especial aquellos que se refieren al uso de la fuerza de los encargados de la seguridad pública y al derecho de acceso a la justica de la población migrante, considerando que se ha incrementado la movilidad humana en América Latina, a consecuencia de la pobreza, la violencia, la falta de oportunidades de desarrollo, los abusos de quienes ejercen el poder público y las respuestas, que no en pocas ocasiones son: discriminación, racismo, segregación, explotación, trata de personas, homicidios, situaciones que deben abordarse bajo la perspectiva de los derechos humanos para proteger a toda persona sin distinción, sin importar la nacionalidad. El método utilizado se basó en la investigación documental de carácter deductivo e interpretativo de la jurisprudencia interamericana y su impacto en la praxis mexicana en los órganos jurisdiccionales sobre casos de migración irregular y datos estadísticos de este fenómeno social.
“Chief, I think we can make this work.” Perceptions of successes and failures in technology implementation from Canadian police leaders
Authors: Brown James , Doucet Michael
Published: December 2020

This article looks at the pressures, issues, and organizational elements that were perceived to have the greatest impact on the success or failure of technology projects, based on discussions with police leaders who have recently retired from police organizations across Canada. These discussions were technology-agnostic and focused on the human dimension of technology projects to understand what worked, what didn’t, and why, with the intent to help inform the discussion on technology acquisition for today’s police leaders.
Indígenas na Universidade: uma comunidade criativa de práticas em Design colaborativo
Authors: Cavalcante Ana Luisa Boavista Lustosa , Devergenes Natalia Maria
Published: December 2020

A colaboração é um aspecto essencial da atividade contemporânea do Design, pois atende às necessidades da Nova Economia que direciona a reconfigurações estruturais nos modos de vida, produção e consumo. Comunidades criativas são casos promissores de iniciativas locais que provocam descontinuidades sistêmicas rumo à sustentabilidade. Este artigo objetiva contextualizar duas oficinas de Design entre indígenas e não-indígenas da Universidade Estadual de Londrina a partir dos conceitos de Comunidades Criativas e Comunidades de Prática. Para tanto, foi realizada uma sistematização dos referenciais teóricos e dos registros etnográficos das oficinas em mapas mentais para comparação conceitual. A pesquisa é de natureza exploratória e descritiva, pautada na metodologia qualitativa da pesquisa social. Os resultados mostram que há uma relação entre as Comunidades Criativas e de Prática no contexto da Sustentabilidade Sociocultural; e que as oficinas realizadas são casos promissores de inovação no processo de Design.
Ensino Remoto Emergencial em um curso de Medicina
Authors: Fossa Rodolffo da Silva , Benedetti André Campos , Esteves Patricia Elisa do Couto Chipoletti , Silva Rinaldo Henrique Aguilar da
Published: December 2020

Como tem acontecido em outros cursos presenciais, as metodologias de ensino de diversos cursos de formação médica foram adaptadas em função do isolamento social imposto pela pandemia do SARS-CoV-2. Assim, muitas instituições de ensino superior passaram a adotar o Ensino Remoto Emergencial (ERE) com o intuito de não paralisar suas atividades acadêmicas. O objetivo deste trabalho foi avaliar a implantação do ERE em uma Faculdade de Ciências Médicas localizada em São José dos Campos, São Paulo, Brasil, a partir da perspectiva discente. A pesquisa é de natureza qualiquantitativa, do tipo Estudo de Caso. A análise dos resultados demonstrou a adaptação e a satisfação dos estudantes com a sequência didática adotada, que alternou metodologias assíncronas e síncronas, em especial a utilização dos vídeos gravados pelos professores. Esses resultados podem fornecer dados aos estudos que buscam investigar o impacto das tecnologias digitais na formação de alunos do ensino superior, porém devem ser considerados a partir do contexto em que foram adotados.
La interactividad de las herramientas tecnológicas en el desarrollo del pensamiento lógico en educación básica secundaria
Authors: Valbuena Bohórquez Angélica Rocio , Alvarado Ortíz Juan Jesús
Published: December 2020

El proyecto demostró la incidencia de la interactividad de las herramientas tecnológicas en el desarrollo del pensamiento lógico matemático en estudiantes de Educación Básica Secundaria grado séptimo. El objetivo era establecer la incidencia de la interactividad de herramientas tecnológicas en el desarrollo del pensamiento lógico matemático en estudiantes de educación Básica Secundaria. Con este fin la pregunta de investigación fue la siguiente: ¿Cómo la interactividad con herramientas tecnológicas promueve el pensamiento lógico matemático en los estudiantes de Educación Básica Secundaria grado séptimo de la Institución Educativa Normal Superior de Pitalito IENSP – Huila durante el periodo académico 2019-2020? Los individuos estudiados fueron 41 estudiantes entre los 11 y 13 años provenientes de estratos sociales 1 y 2 sin ninguna discapacidad o problema de aprendizaje. El tipo de investigación utilizada fue la cualitativa ya que interpreta observando y analizando la población de manera que contribuye al desarrollo de los procesos para obtener los resultados de la investigación mediante el enfoque investigación acción. Las técnicas que se utilizaron fueron: la observación con su instrumento la ficha de observación, la entrevista con su instrumento la guía de entrevista, la encuesta con su instrumento el cuestionario, las experiencias personales y la discusión en grupo.
Personalistic and Utilitarian View of Marriage According to Early Wojtyła
Authors: Wilk Rafał Kazimierz
Published: December 2020

The main goal of this paper is to present the philosophical (i.e. attained by the light of natural reason) explanation of the marital relationship according to the Polish philosopher Karol Wojtyła. In our research, our attention was focused mainly on his book Love and Responsibility; the early philosophical work of a young, 37 year old Professor of Philosophy at the Catholic University in Lublin, Poland. In his writings, Karol Wojtyła—the future Pope John Paul II—presents marriage as a monogamous, indissoluble relationship between a man and a woman, which grows out of mutual love for the purpose of procreation. Such a relationship is ruled by the „personalistic norm" which says that a person can never, under any circumstances, be a mere object of enjoyment for another person, but can only be the object (co-object) of love. Love is a self-giving for the good of one's counterpart, so Marriage as a personalistic unity persists as long as these persons are alive. Because love is fecund from its very essence, so it is fruitful from its nature. Thus, procreation belongs to the principle ends of marriage. Such an attitude—as K. Wojtyła proves—is opposed to the utilitarian point of view of man and Marriage. According to the utilitarian conception, a person can be used as a means for achieving the highest good, i.e., pleasure.
EFEKTIVITAS PENDAPATAN DAERAH KABUPATEN PACITAN DALAM PROSES PEMULIHAN PASCA BENCANA
Authors: Ningsih Devi Nur Cahaya
Published: December 2020

Flood and landslide that occurred at the end of 2017 in Pacitan Regency induced huge losses. However, with good cooperation from all levels of The Pacitan's society, the impact of the disasters could resolve in 4 months. This study aims to determine the steps taken by the government of Pacitan Regency to achieve effectiveness in realizing the original regional income of Pacitan Regency, especially for post-disaster recovery. The research method used is descriptive qualitative, through interviews with the Head of the Disaster Management Section of Pacitan Regency. The results obtained indicate The government of Pacitan Regency has policies that can secure their Original Regional Income. The Regional Original Income is always achieved well before disasters, during disasters, and after disasters. Apart from implementing policies, the effectiveness of regional income in the time of disaster recovery process in Pacitan Regency is also encouraged by the assistance funds obtained from the central government, regional governments, and the private sector. Meanwhile, involving the community with an attitude of good cooperation that is one of a characteristic of the Indonesian society could quickly restore the condition of the Pacitan Regency.
Enhanced in-plane uniformity and breakdown strength of diamond Schottky barrier diodes fabricated on heteroepitaxial substrates
Authors: Sittimart Phongsaphak , Ohmagari Shinya , Yoshitake Tsuyoshi
Published: December 2020

In this study, pseudo-vertical diamond Schottky barrier diodes (SBDs) were fabricated on heteroepitaxial substrates and a metal impurity-incorporated buffer layer to suppress killer defects was inserted. All SBDs exhibited excellent rectifying actions with suppressed leakage current. The in-plane uniformity was improved after the insertion of the buffer layer. Forward characteristics were fitted by thermionic emission theory and Tung’s model in the temperature range from 300 to 480 K. The perfection of the Schottky-diamond interface is discussed. Moreover, the SBDs exhibited a high breakdown voltage with a sudden increase in current at 375 V, which is the highest value reported for heteroepitaxial diamond. These results indicate that heteroepitaxial substrates are a promising alternative for large-area low-cost diamond electronics.
Etching-induced damage in heavily Mg-doped p-type GaN and its suppression by low-bias-power inductively coupled plasma-reactive ion etching
Authors: Kumabe Takeru , Ando Yuto , Watanabe Hirotaka , Deki Manato , Tanaka Atsushi , Nitta Shugo , Honda Yoshio , Amano Hiroshi
Published: December 2020

Inductively coupled plasma–reactive ion etching (ICP–RIE)-induced damage in heavily Mg-doped p-type GaN ([Mg] = 2 × 1019 cm−3) was investigated by low-temperature photoluminescence (PL) and depth-resolved cathodoluminescence (CL) spectroscopy. From PL measurements, we found broad yellow luminescence (YL) with a maximum at around 2.2–2.3 eV, whose origin was considered to be isolated nitrogen vacancies (V
N), only in etched samples. The depth-resolved CL spectroscopy revealed that the etching-induced YL was distributed up to the electron-beam penetration depth of around 200 nm at a high ICP–RIE bias power (P
bias). Low-bias-power (low-P
bias) ICP–RIE suppressed the YL and its depth distribution to levels similar to those of an unetched sample, and a current–voltage characteristic comparable to that of an unetched sample was obtained for a sample etched with P
bias of 2.5 W.
SENTIMENTOS DE ADOLESCENTES QUE SE SUBMETERAM AO ABORTAMENTO PROVOCADO
Authors: Rigo Deise , Marchetri  Pin Valeska , Moretti Eleonor
Published: December 2020

Este estudo possibilitou o desvelamento dos sentimentos de adolescentes que se submeteram ao abortamento provocado, dos motivos que influenciaram na sua decisão de interromper a gravidez e das formas de indução do abortamento. Isso foi possível através de estudo exploratório-descritivo de abordagem qualitativa, em que foram entrevistadas adolescentes que compareceram à emergência de um hospital geral de grande porte da região do Planalto do Rio Grande do Sul, no período de julho a outubro de 2000. Os dados foram coletados através de entrevistas e anotações de campo. Como resultados, encontraram-se os seguintes dados:1) os sentimentos encontrados foram: tristeza, depressão, desespero, alívio, liberdade, dor do pecado, pavor,medo de humilhações e vergonha; 2) os motivos que levaram ao abortamento: a idade, a família, a falta de preparo para assumir uma gestação e, posteriormente, uma criança, a instabilidade no relacionamento, as condições socioeconômicas e a desinformação sobre métodos contraceptivos; 3) os métodos utilizados para provocar o abortamento foram: chás, sondas e Cytotec (methotrexateJ. Em vista disso, recomenda-se aos profissionais da área que reflitam sobre a prática de suas atividades quanto à educação sexual e à assistência por eles prestada em âmbito hospitalar, devendo ser realizadas de novas pesquisas para que esses assuntos sejam aprofundados.
PROJETO GÊNERO E TRANSGENITALIZAÇÃO
Authors: Canella Paulo , Do Carmo Andrade-Silva Maria
Published: December 2020

São abordados os inúmeros e complexos componentes do núcleo de base do sentimento que compõe a identidade de gênero. O transexual apresenta um sentimento de infelicidade, derivado da inadequação entre a realidade psíquica e seu corpo físico, sendo os únicos disfóricos em que há indicação para a trasgenitalização. O transtorno de identidade de gênero é caracterizado segundo o Manual Diagnóstico e Estatístico de transtornos Mentais, (2002) da Associação Americana de Psiquiatria. O projeto de Pesquisa desenvolvido neste trabalho pode ser dividido em quatro etapas: Primeira Fase -avaliações físicas (funcionais, genitais, hormonais) e psicológicas (psiquiátricas e sexológicas); Segunda fase - confirmado o transexualismo, preparação para a efetivação da transgenitalização; Terceira fase -realização do tratamento cirúrgico de transexualização; Quarta Fase -acompanhamento sistemático, após o procedimento cirúrgico. Serão apresentados dois casos de pacientes do projeto Gênero e Trasgenitalização: o primeiro, do masculino para o feminino já na quarta fase, tendo cumprido com êxito as três primeiras fases; o segundo, do feminino para o masculino,o qual se encontra na terceira fase do projeto.
Rancangan Trucking Collaboration System
Authors: Armiati Sari , Choldun Muhammad Ibnu
Published: December 2020

Perusahaan logistik bergerak di bidang jasa pengiriman memiliki kegiatan pengiriman dan penerimaan barang. Biasanya memiliki divisi Departemen Logistik yang bertanggung jawab untuk menangani pengembangan bisnis logistik, manajemen proyek logistik, termasuk pemilihan vendor, membuat laporan rekapitulasi tagihan dari vendor dan mengirimkan tagihan kepada pelanggan. Dalam penelitian ini pengamatan proses bisnis dilakukan di PT XYZ yang memiliki bisnis pengiriman barang. Proses bisnis yang terjadi saat ini, para vendor yang telah terdaftar di PT XYZ akan memberikan layanan transportasi untuk barang pengiriman yang dimiliki oleh mitra PT XYZ sesuai dengan dimensi jenis, volume, ukuran dan berat barang. Butuh waktu lama bagi Departemen Logistik untuk memilih vendor baru, rekapitulasi penagihan oleh admin penagihan juga dibuat dalam format yang berbeda dan tidak ada penyimpanan data yang tepat di Departemen Logistik. Berdasarkan kebutuhan ini, diperlukan desain aplikasi sistem kolaborasi truk di perusahaan PT XYZ yang memiliki kemampuan fungsional untuk mengelola data pemilihan vendor, mengelola rekapitulasi tagihan, dan melindungi data. Desain aplikasi ini akan menjadi pedoman dalam mengimplementasikan perangkat lunak pada penelitian selanjutnya.
Technology Acceptance Model (TAM) untuk Menganalisis Penerimaan Pengguna Terhadap Penggunaan Aplikasi Belanja Online XYZ
Authors: Pibriana Desi
Published: December 2020

Perkembangan teknologi dan informasi di jaman sekarang khususnya internet mengalami perkembangan yang sangat pesat. Internet menghubungkan satu orang dengan orang lainnya, menyediakan informasi, sebagai sarana hiburan, maupun sebagai sarana komunikasi. Aplikasi belanja online XYZ merupakan suatu aplikasi dari PT. XYZ yang digunakan untuk melakukan penjualan produk secara online. Setelah survei sederhana kepada 50 orang, diketahui sebanyak 13 orang merupakan pengguna aplikasi belanja online XYZ dan memiliki pendapat yang positif. Untuk mengetahui lebih lanjut apakah pendapat dari 13 orang tersebut dapat mewakili pendapat para pengguna aplikasi belanja online XYZ secara keseluruhan, maka perlu diketahui tingkat penerimaan pengguna terhadap penggunaan aplikasi belanja online tersebut, untuk mengetahui tingkat penerimaan para pengguna, maka digunakanlah metode Technology Acceptance Model (TAM). Dalam melakukan pengumpulan data, penulis  menggunakan survey research dengan sampel 365 responden dan untuk analisis data, tools yang digunakan adalah software SPSS untuk menguji validitas dan reliabilitas instrumen variabel dan SmartPLS untuk menguji model. Hasil dari penelitian ini yaitu dari 7 hipotesis yang diajukan,ketujuh hipotesis tersebut dapat diterima dan berpengaruh positif.
OTOMATISASI PENDISTRIBUSIAN ZAKAT PADA BADAN AMIL ZAKAT NASIONAL PROV. KEP. BANGKA BELITUNG
Authors: Pradana Harrizki Arie
Published: December 2020

Baznas Prov. Kep. Bangka Belitung merupakan badan pengelola zakat yang didirikan berdasarkan undang-undang nomor 38 tahun 1999. Baznas merupakan badan yang menghimpun dan menyalurkan zakat yang diperoleh. Dalam proses penyaluran zakat, terdapat hal-hal yang dinilai masih kurang efektif antara lain pendataan penduduk yang sudah pernah mendapatkan dan yang belum pernah mendapatkan masih tumpang tindih, serta masih terjadinya kesulitan dalam pembuatan dokume yang dibutuhkan dalam proses penyaluran zakat dan infaq. Dengan adanya masalah tersebut dalam penelitian diusulkan untuk membangun sebuah sistem yang terkomputerisasi. Metode berorientasi objek dengan menggunakan Unified Modelling Language sebagai tools digunakan dalam analisis maupun perancangannya. Teknologi yang digunakan dalam pengembangan perangkat lunak sistem menggunakan Php sebagai bahasa pemrogramannya dan My SQL sebagai database. Sistem ini diharapkan dapat meningkatkan kinerja Baznas Prov. Kep. Bangka Belitung dalam hal penyaluran zakat.
Rural Entrepreneurship through Cow Based Products
Authors: Tyagi K.S. , Singh D.P. , Sharma T.C. , Gupta R.K.
Published: December 2020

Indian agriculture is typically characterized by an essential symbiosis of crop and livestock production. Cattle rearing contribute substantially to economic and nutritional security of rural households.  Lately, there has been a concern about viability of cattle husbandry at domestic household level mainly because of low milk yield and increased cost of maintaining cattle without substantial land under farming.  The  Department of Rural Studies and Sustainability at Dev  Sanskriti Vishwavidyalaya (DSVV), Haridwar has developed eleven technologies for cow urine and cow dung  based products viz. soaps, face pack, tooth powder, dhup batti, eye drops, distilled cow urine (Ark), pain–relief massage oil etc. These value added products has helped over 52 cattle owners to make cattle husbandry a profitable enterprise. Besides promotion of cow based therapies, it has provided substantial opportunities for employment of unskilled and semi-skilled youths in rural areas.  Over 50 large cow urine and dung based products production units are presently operating in various parts of the country based on the training imparted at DSVV. The paper describes value added products which can be manufactured using cow dung and urine and can help in enhancing income of cattle owners.
EFFECT OF DIFFERENT FOOT ARCH SUPPORTS ON DYNAMIC BALANCE IN NURSING PROFESSIONALS WITH FLATFOOT
Authors: Naseem Summaiya , Imran Farooqui Sumaira , Farhad Ali , Parveen Ishrat , Jabeen Tayyaba
Published: December 2020

BACKGROUND
Flat foot, depletion of medial longitudinal arch affects almost
20% of adult global population; approximately 9-14% of
schools going children are flat foot making the gender wise
prevalence of about 13% girls and 7% boys, 11.25% population
of age group between 18-25 years are diagnosed as flat
footed.

AIM
The focus of this study is to device best possible strategy for the
nurses to overcome their deformity and live as normal and
pain free professional life as possible by providing foot supports
that bring foot arches to normal or near normal position.

METHOD
The subjects were divided into two groups. Group A and
Group B. Group A was asked to wear medial wedge support
and group B was prescribed heel support for 3 weeks.

RESULTS
Result shows that both the orthosis are useful in forming the
arch of foot, improving the dynamic balance and relieving the
symptoms of flatfoot but medial wedge is found to be more
efficient as compared to heel support.
EFFECT OF NDT IN IMPROVING MOTOR DYSFUNCTION USING GMFM SCORE 66 AND 88 AS ASSESSMENT TOOLS
Authors: Farhad Ali , Shafaq Sadia , Aamir Khan Amna
Published: December 2020

ACKGROUND AND AIM
Globally, the prevalence of motor dysfunction among the
pediatric population is 2.33 per 1000 live births where NDT is an
advance treatment protocol widely used by the pediatric
physical therapist to improve Gross Motor Function. Several
measuring scales are used worldwide but GMFM score is
considered as consistent, accurate, safe, and sensitive and
gold standard. The aim of this study is to determine the
outcomes of NDT according to GMFM score 66 and 88 in
children with motor dysfunction.

STUDY DESIGN
An experimental study.
SAMPLING TECHNIQUE
Non-probability, convenience sampling technique.
SAMPLE SIZE
40 children with motor dysfunction aged between 1 to 12
years.

INTERVENTION
Group A comprises of children with CP receiving NDT protocol
for 4 months; were assessed pre and post via GMFM 66 whereas
Group B comprises of children with DS and DD receiving the
similar treatment protocols; were assessed pre and post via
GMFM 88.

RESULT
The mean ±SD of Pre GMFM 66 and 88 scores were 45.2 ±9.4
and 43.2 ±25.4 respectively whereas post values were 49.6
±11.3 and 50.7 ±25.6. NDT shows significant results in Group B
when measured on the GMFM-88 (P< 0.03)

CONCLUSION
NDT is found to be more effective treatment among the DD
and DS as compared to CP.
CORRELATION BETWEEN LOW BACK PAIN AND RECTUS ABDOMINIS MUSCLE WEAKNESS USING KENDALL’S GRADING SCALE
Authors: Khan Urooj , Kayenat Sana , Usman Khadija , Kumar Vinesh
Published: December 2020

BACKGROUND
Kendall’s approach is used to test the muscles strength and to
determine the correct alignment of the muscle fibers. The
major causes of back pain are work related problem,
mechanical stress on muscles and faulty postures, which leads
to core muscle weakness particularly rectus abdominis or may
cause DRA. Thus the study aims to identify a causal relationship
between low back pain and rectus abdominis muscle
weakness using Kendall’s grading scale.
STUDY DESIGN
Cross Sectional Study
SAMPLING TECHNIQUE
Non-probability convenience sampling technique
METHODOLOGY
142 (men 33.80% and women 66.20%) participants with low
back pain were recruited in the study. The Kendall grading
scale test the strength of muscles of the upper and lower
rectus abdominis muscles among the participants while
self-administered questionnaire was used to identify the
nature of the back pain.
RESULT
Sperman’s rho coefficient of correlation was applied to find
out the cause effective correlation between the two
variables, result shows no significant cause effective correlation
between the upper and lower back pain and lower
rectus abdominis muscles weakness (P>0.05) with r= 0.065 and
r=0.031respectively.
CONCLUSION
Although core muscle weaknesses are the source of back
pain but no significant cause effective correlation exist
between the two variables in this study.
Iniciativas contra-hegemónicas de povos indígenas no Amazonas, Brasil.
Authors: Neves Lino João de Oliveira
Published: December 2020

The article is dedicated to study of indigenous movements in the state of Amazonas in Brazil.