bluuebunny/crossref_metadata_2025 huggingface dataset:
A study on the influence of the formulation factors on in vitro release of ketoprofen from sustained release tablets
Authors:   Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania, Cimpoaie Larisa , Rus Luca Liviu ,   Preclinical Department, Faculty of Medicine, “Lucian Blaga” University, Sibiu, Romania, Iovanov Rareș Iuliu ,   Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
Published: May 2021

Objectives. The aim of this study was to investigate the influence of formulation factors on in vitro release of ketoprofen from sustained release inert matrix tablets. Materials and methods. Laboratory scale, Ketoprofen sustained release inert matrix tablets were manufactured using Kollidon® SR as matrix formator, by direct tableting of powder blends. The influence of the formulation factors (X1 – matrix formator excipient and X2 – diluent type) on in vitro release of ketoprofen from sustained release tablets was studied by using a full factorial 23 experimental plan. Outcomes. Pharmacotechnical characterization of manufactured laboratory scale batches was performed and all 12 batches fulfilled European Pharmacopeia requests. In vitro release showed a sustained release profile in all cases. Variance analysis (ANOVA) showed a good correlation between experimental conditions and answers. In vitro release testing was performed in phosphate buffer pH = 7.4. Percentage release was determined spectrophotometrically at 258 nm. A decrease in the rate of in vitro release was registered, up to 4 h and 6 h when lactose DC and mannitol DC were used as diluents, respectively. Isomalt DC has increased the rate of in vitro release up to 6 h. Conclusions. In vitro release data, corresponding to formulation N1 shoed a good fitting with Weitbull, Korshmeyer-Peppas and Higuchi models while in vitro release data corresponding to formulation N8 presented a good fitting with Weitbull and Korsmeyer-Peppas. In case of formulations N1 and N8 a non-Fickian diff usion mechanism seems to be involved in drug release from the matrix tablets.
TRUE ILEAL AVAILABILITY OF AMINO ACIDS IN CEREAL GRAINS FOR ADJUSTING PIGLETS RATIONS
Authors:   All-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals ‒branch of the Federal Scientific Center for Animal Husbandry ‒ VIZh named after academician L.K. Ernst, NIYAZOV N.S.-A. , PYANKOVA E.V. ,   All-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals ‒branch of the Federal Scientific Center for Animal Husbandry ‒ VIZh named after academician L.K. Ernst
Published: May 2021

The faecal and true ilealavailability (IIDs)of amino acids from wheat, barley, triticale, and maize was studied by applying a T-shaped cannula in the lower ileum. When calculating the amino acid score of cereals, it was found that the first limiting acid is ‒ lysine, the second threonine, the third ‒methionine+cystine (for wheat, barley and corn) and for triticale ‒ isoleucine and valine. The obtained estimates of the amino acids of feed components should be used in the development of complete feed for pigs.
From demand economy to economy of supply?
Authors: Kapkanschikova Svetlana , Kapkanschikov Sergey
Published: May 2021

In this article the authors question the effectiveness of Russia’s government policy aimed at transition from demand economy to economy of supply. The authors argue that Russian financial policymakers incorrectly treat cyclical budget deficit as structural. Such approach creates an additional barrier to an aggregate demand growth in Russia’s economy, which still remains in recession. Revival of financial policymakers’ trend to excessive accumulation in the National Welfare Fund, post-election cuts in budget social spending and infrastructure investment together with extremely high interest rates pose a considerable threat to the national security. Revealing the effect of restrictive fiscal and monetary policies on deepening the recession, the authors identify the growth dilemma for Russia’s economy — either an inevitable halt or a radical shift to a new quality.
Dependence of Solar Wind Proton Temperature on the Polarization Properties of Alfvénic Fluctuations at Ion-kinetic Scales
Authors: Woodham L. D. , Wicks R. T. , Verscharen D. , TenBarge J. M. , Howes G. G.
Published: May 2021

We use fluctuating magnetic helicity to investigate the polarization properties of Alfvénic fluctuations at ion-kinetic scales in the solar wind as a function of β

p
, the ratio of proton thermal pressure to magnetic pressure, and θ

vB
, the angle between the proton flow and local mean magnetic field,
B

0. Using almost 15 yr of Wind observations, we separate the contributions to helicity from fluctuations with wavevectors,
k
, quasi-parallel and oblique to
B

0, finding that the helicity of Alfvénic fluctuations is consistent with predictions from linear Vlasov theory. This result suggests that the nonlinear turbulent fluctuations at these scales share at least some polarization properties with Alfvén waves. We also investigate the dependence of proton temperature in the β

p
–θ

vB
plane to probe for possible signatures of turbulent dissipation, finding that it correlates with θ

vB
. The proton temperature parallel to
B

0 is higher in the parameter space where we measure the helicity of right-handed Alfvénic fluctuations, and the temperature perpendicular to
B

0 is higher where we measure left-handed fluctuations. This finding is inconsistent with the general assumption that by sampling different θ

vB
in the solar wind we can analyze the dependence of the turbulence distribution on θ

kB
, the angle between
k
and
B

0. After ruling out both instrumental and expansion effects, we conclude that our results provide new evidence for the importance of local kinetic processes that depend on θ

vB
in determining proton temperature in the solar wind.
The HETDEX Survey: The Lyα Escape Fraction from 3D-HST Emission-Line Galaxies at z ∼ 2
Authors: Weiss Laurel H. , Bowman William P. , Ciardullo Robin , Zeimann Gregory R. , Gronwall Caryl , Mentuch Cooper Erin , Gebhardt Karl , Hill Gary J. , Blanc Guillermo A. , Farrow Daniel J. , Finkelstein Steven L. , Gawiser Eric , Janowiecki Steven , Jogee Shardha , Schneider Donald P. , Wisotzki Lutz
Published: May 2021

In this work, we measure the Lyα escape fraction of 935 [O iii]-emitting galaxies between 1.9 < z < 2.35 by comparing stacked spectra from the Hubble Space Telescope/WFC3's near-IR grism to corresponding stacks from the Hobby–Eberly Telescope Dark Energy Experiment’s Internal Data Release 2. By measuring the stacks’ Hβ to Lyα ratios, we determine the Lyα escape fraction as a function of stellar mass, star-formation rate, internal reddening, size, and [O iii]/Hβ ratio. We show that the escape fraction of Lyα correlates with a number of parameters, such as galaxy size, star-formation rate, and nebular excitation. However, we also demonstrate that most of these relations are indirect, and that the primary variables controlling the escape of Lyα are likely to be stellar mass and internal extinction. Overall, the escape of Lyα declines from ≳16% in galaxies with

to ≲1% for systems with

, with the sample’s mean escape fraction being

.
Resolving the Hot Dust Disk of ESO323-G77
Authors: Leftley James H. , Tristram Konrad R. W. , Hönig Sebastian F. , Asmus Daniel , Kishimoto Makoto , Gandhi Poshak
Published: May 2021

Infrared interferometry has led to a paradigm shift in our understanding of the dusty structure in the central parsecs of active galactic nuclei (AGNs). The dust is now thought to comprise a hot (∼1000 K) equatorial disk, some of which is blown into a cooler (∼300 K) polar dusty wind by radiation pressure. In this paper, we utilize the new near-IR interferometer GRAVITY on the Very Large Telescope Interferometer (VLTI) to study a Type 1.2 AGNs hosted in the nearby Seyfert galaxy ESO 323-G77. By modeling the squared visibility and closure phase, we find that the hot dust is equatorially extended, consistent with the idea of a disk, and shows signs of asymmetry in the same direction. Furthermore, the data is fully consistent with the hot dust size determined by K-band reverberation mapping as well as the predicted size from a CAT3D-WIND model created in previous work using the spectral energy distribution of ESO 323-G77 and observations in the mid-IR from VLTI/MID-infrared Interferometric instrument).
X-Ray AGB Stars in the 4XMM-DR9 Catalog: Further Evidence for Companions
Authors: Ortiz R. , Guerrero M. A.
Published: May 2021

Single AGB stars are not normally expected to be X-ray emitters due to the lack of a corona capable of powering a hot plasma. Therefore, the detection of X-ray emission in AGB stars by the ROSAT, Chandra, and XMM-Newton observatories has been interpreted as evidence for binarity. The number of X-ray-emitting AGB stars is, however, very small, and statistically sound conclusions shall be considered tentative. In this paper we aim at increasing the number of X-ray-emitting AGB stars and at providing a consistent analysis of their X-ray emission to be compared to their UV and optical properties. The XMM-Newton 4XMM-DR9 catalog has been searched for X-ray counterparts of various types of AGB stars: nearby (i.e., listed in Hipparcos), mass-losing, and S- and C-types. Seventeen X-ray counterparts of AGB stars have been found in the 4XMM-DR9. Nine of them have pointed XMM-Newton observations, whereas eight are genuine serendipitous discoveries. Together with the AGB stars detected by ROSAT, this increases the number of X-ray AGB stars to 26. Most of their X-ray spectra can be fit by the emission from an optically thin single-temperature thermal plasma with temperatures typically larger than 107 K. There is no obvious correlation between the X-ray and bolometric luminosity of these stars, but the X-ray luminosity generally increases with the amount of far-UV excess. The high temperature of some X-ray-emitting plasma in AGB stars and the correlation of their X-ray luminosity with the far-UV emission supports the origin of this X-ray emission from accretion disks around unseen companions.
Potential Bone Regenerative Effects of DFDBA, Simvastatin and Platelet Rich Fibrin, Radiographically and Histologically of Intra-Bony Periodontal Defects in White New Zealand Rabbits
Authors: El-dien Asma M. Sarag , Fathy Shereen , El-din Yasmine Alaa
Published: May 2021

AIM: This study aimed to evaluate and to compare the regenerative power of simvastatin, Demineralized Freeze-Dried Bone Allograft (DFDBA) allograft, platelets rich Fibrin (PRF), and a combination of these materials radiographically and histologically in the intra-bony periodontal defects in white New Zealand rabbits. MATERIALS AND METHODS: This study was conducted on 54 defects in 27 adult male rabbits (n = 27) which were divided into three groups according to the follow-up preplanned scheduled for 1, 2, and 3 weeks. The selected materials were induced as following: A=DFDBA, B=Simvastatin, C= PRF, D=A+C, E=B+C, and F=negative (control group). The intra-bony periodontal defects were induced as the form of one osseous wall defect of 10 mm height, 4 mm depth between the first and the second molars. Then, samples were prepared for histological evaluation. Radiographic assessment was done using computed tomography radiography which was carried at different time intervals as the following baseline, 1, 2, and 3 weeks later. Statistical analysis was performed using ANOVA. RESULTS: After evaluating the results, macroanatomy, radiographically, and histologically, it is thus confirmed that DFDBA allograft combined with PRF create the best bone regenerative results, followed by DFDBA, Simvastatin, simvastatin+ PRF, control group, and finally PRF. CONCLUSION: All of the materials examined in this study showed different percentage in terms of bone density and bone regenerative effects. However, the best results for bone density of the DFDBA + PRF group were recorded after 3 weeks. Thus, the study concludes that a combination of DFDBA + PRF reflects the best properties of both materials in terms of bone density results of the defect. Such results are particularly significant for the selection of bone regeneration materials, and generally, for periodontal regeneration.
Knowledge and Attitude of Medical Students at the Universitas Sumatera Utara toward Lifestyle that Contributes to Type 2 Diabetes
Authors: Raphaella Raphaella , Sari Mutiara Indah
Published: May 2021

BACKGROUND: Diabetes mellitus is a chronic metabolic disease with an increased blood glucose level. Lifestyle in the form of wrong diet and low or inadequate physical activity affect to type 2 diabetes.
AIM: The purpose of this study was to determine the level of knowledge and attitude of medical students at the Universitas Sumatera Utara regarding diet and physical activity that contribute to type 2 diabetes.
METHODS: Class 2017 medical students at the Universitas Sumatera Utara who met the inclusion and exclusion criteria were asked to participate as respondents in this cross-sectional study. Respondents were asked to answer online-based questionnaires containing 14 knowledge questions and 14 attitude statements about lifestyle towards type 2 diabetes. Knowledge scores equal to above 11 were categorized as good knowledge, and attitude scores equal to above 42 were categorized as good attitude. The data were presented as frequencies and percentage proportions using SPSS program version 22.
RESULTS: Out of 255 class 2017 medical students, 72 students were respondents in this study. The results showed that the level of knowledge and attitude of medical students regarding diet that plays a role in type 2 diabetes in the good, moderate, and poor categories were 94.4%, 4.2%, 1.4% and 58.3%, 41.7%, 0%, respectively. The level of knowledge and attitude regarding physical activity that plays a role in type 2 diabetes in the good, moderate, and poor categories were 97.2%, 1.4%, 1.4% and 33.3%, 66.7%, 0%, respectively.
Conclusions: In this study, it was shown that the knowledge and attitude of medical students at the Universitas Sumatera Utara towards eating pattern that contributes in type 2 diabetes were in line, namely the percentage of good categories was the highest percentage for each knowledge and attitude, but different results were found on the level of knowledge and attitude for physical activity.
The Impact of Tourism on the Quality of Life of Communities in Tourist Destination Areas: A Systematic Review
Authors: Nopiyani Ni Made Sri , Wirawan I Md Ady
Published: May 2021

BACKGROUND: Tourism development can have a positive or negative impact on the lives of local communities.
AIM: This systematic review aims to determine the impact of tourism on the quality of life (QoL) of people in tourist destination areas.
METHODS: The search was conducted on the Science Direct database, Taylor Francis, EBSCO Host, Wiley Online Library, and Google Scholar. The keywords used were “residents’ QoL” AND impacts of tourism. Inclusion criteria were articles that focus on the QoL of people in tourist destination areas, published from 2015 to 2019 in peer-reviewed journals, in English. Articles were excluded if they were qualitative studies, literature reviews, and if full papers were unavailable. The review was conducted on 18 articles selected from 673 articles obtained in the initial search.
RESULTS: Tourism has an impact on the QoL of local communities. In general, the domains that are perceived as being positively affected are the improvement of the economy, employment opportunities, community pride, cultural exchanges, and increased facilities availability. Meanwhile, the domains that are negatively affected in most of the studies are health, safety, quality of the physical environment, cost of living, accessibility to public facilities, and social relations. Apart from that, there is also dissatisfaction with the types of jobs available and the low level of community involvement in tourism development.
CONCLUSIONS: Tourism can have both positive and negative impacts on the QoL of local communities. Efforts to minimize the negative impacts of tourism should be undertaken to improve community support for tourism development.
Small Axe and the big tree of 2020
Authors: Naidoo Roshi
Published: May 2021

This article reflects on Steve McQueen's Small Axe series, exploring its importance in placing black narratives at the centre of history and on prime time television. It locates it within the context of a longer history of struggles over black representation and misrepresentation in
mainstream British media. Naidoo draws on her own experiences to discuss the very slow progress towards diversity in the cultural life of Britain. She pays tribute to pioneers who campaigned for a more representative media in Britain. What made these films especially important was the space
given to pleasure, presence and collective joy.
The legacies of British slave ownership Catherine Hall talks to Ruth
Authors: Hall Catherine , Ramsden-Karelse Ruth
Published: May 2021

The Legacies of British Slave Ownership project has explored the significance of slavery to Britain's history, including in the wealth it generated for industrialisation. Such research is crucial for understanding the present, given that disavowal of these legacies has been central
to white British thinking. Its mapping of compensation awarded after abolition showed the widespread incidence of slave ownership across the whole of the UK. A further legacy has been the way ideas on race developed by white plantation owners still inform contemporary thinking. An important
first step towards reparation is understanding and knowing what happened, and breaking the patterns of denial.
Can a re-animated New Deal see off Trump Republicanism?
Authors: Seaton Matt
Published: May 2021

Because of the quirks of the US constitution, Democrats find it difficult to assemble an electoral coalition capable of delivering working majorities in both chambers of Congress and a Democrat president. In the 2020 elections, Biden's electoral college victory was secured by 44,000
votes, distributed in three states. Republicans currently hold 59 state chambers to the Democrats' 39, and they will use this to further gerrymander boundaries and suppress votes. Trump took Reagan's Republican strategy - small government, populism and mobilising conservatives - to a logical
conclusion by seeking to wreck government as a deliberate strategy and mobilising right-wing extremists to support his rule. Repairing Americans' faith in government is a long term task . However, Biden's continuing allegiance to the ideas of the New Deal, and the recognition the party must
now give to its grassroots activists, particularly in black communities, may help to energise the Democrat coalition.
Is Macron the persuader reaching the end of the road?
Authors: Myant Chris
Published: May 2021

For Emmanuel Macron it is natural that a French President should have the powers of an English Tudor monarch. He also believes in a version of neoliberalism in which the state is rolled back when it comes to protections for workers, welfare support and regulating the economy, but not
in its role in determining everything. Macron was a key Hollande advisor at the time of his U-turn to neoliberalism, and he has been named 'the Great Manipulator'. As French citizens have become increasingly disenchanted with his performance, Macron's political machine, Le République
En Marche!, has crumbled. The signs are that he will now tack further to the populist right.
Mutualism, massive and the city to come: Jungle Pirate Radio in 1990s London
Authors: Cordell Tom , James Malcolm
Published: May 2021

1990s Britain was under Thatcherite continuity rule. But radio waves were appearing that carried fragments of the future: weekend broadcasts of a new kind of music - Jungle - were being illegally beamed across the city from the rooftops of tower blocks, appropriating them as the locus
of an alternative cultural infrastructure. Pirate stations used newly emerging technologies to spread subversive sounds from the margins and to challenge dominant cultures.
Perdre des atomes
Authors: Chouinard Isabelle
Published: May 2021

Dans les fragments éthiques, Démocrite présente la vieillesse comme un âge où la modération se manifeste plus facilement que dans la jeunesse (68B294 DK). Le fait qu’il décrive aussi la vieillesse comme une « mutilation intégrale (πήρωσις ὁλόκληρος) » (68B296 DK) laisse croire que sa théorie atomiste a pu servir à rendre compte du phénomène. Comprise comme une perte d’atomes dans toutes les parties du corps, la πήρωσις entraîne avec elle des fuites d’atomes psychiques qui peuvent avoir un effet sur le tempérament des vieillards. Si cette hypothèse est juste, elle s’ajoute au nombre des liens possibles entre la théorie atomiste et les pensées morales de Démocrite.
La sélection des idées incrémentales et radicales : Les enseignements d’une étude de cas
Authors: Ininou Yassine , Loilier Thomas
Published: May 2021

Cet article examine la façon dont les idées émises par les salariés d’une entreprise industrielle sont sélectionnées. Son objectif est d’apporter une compréhension fine et renouvelée de la dimension processuelle de cette étape clé du management de l’innovation et de la créativité. Pour atteindre cet objectif, il explore le processus de décision à l’œuvre au sein de l’entreprise Bosch MoP, en combinant entretiens qualitatifs (auprès de 38 acteurs du processus) et analyse des interactions argumentatives échangées au cours de 4 réunions de délibération du comité d’innovation en charge de la sélection. Les résultats montrent tout d’abord que le processus de sélection des idées diffère dans ses composants, son périmètre organisationnel et ses trajectoires selon que l’on traite des idées incrémentales ou radicales. Ces deux types d’idées font de plus l’objet d’argumentations spécifiques lors les comités d’innovation en charge de décider de leur acceptation ou de leur rejet. Les résultats montrent également que la sélection est bien un processus séquencé, modulable (selon le type d’idées émises) et mixte, où des approches logico-mathématiques et sociales viennent se compléter. Code JEL : O31
Chapitre IV
Authors: Swift Jonathan
Published: May 2021

Description de la capitale de Lilliput, nommée Mildendo, et du palais de l’empereur. Conversation entre l’auteur et un des premiers secrétaires sur les affaires de l’Empire. L’auteur s’offre à servir l’empereur contre ses ennemis.
Chapitre IV
Authors: Swift Jonathan
Published: May 2021

Description du pays. Projet pour la correction des cartes géographiques. Ce que c’était que le palais du roi et la capitale. Manière dont l’auteur voyageait. Description d’un des principaux temples de la capitale.
Chapitre II
Authors: Swift Jonathan
Published: May 2021

Description des Laputiens. Quelles sortes de sciences sont en vogue chez eux. Idée abrégée du roi et de sa cour. Manière dont l’auteur y est reçu. Craintes et inquiétudes auxquelles les habitants sont sujets. Description des femmes.
Chapitre III
Authors: Swift Jonathan
Published: May 2021

Phénomène expliqué par le secours de la philosophie et de l’astronomie moderne. Habileté des Laputiens dans la dernière de ces deux sciences. Méthode du roi pour réprimer les soulèvements.
Chapitre VI
Authors: Swift Jonathan
Published: May 2021

Continuation du même sujet. L’auteur propose quelques nouvelles inventions qui sont reçues avec de grands applaudissements.
Chapitre VIII
Authors: Swift Jonathan
Published: May 2021

Détail curieux touchant la ville de Glubbdubdrib. Quelques corrections de l’histoire ancienne et moderne.
Chapitre XI
Authors: Swift Jonathan
Published: May 2021

L’auteur quitte Luggnagg et va au Japon d’où il se rend sur un vaisseau hollandais à Amsterdam et d’Amsterdam en Angleterre.
Chapitre VI
Authors: Swift Jonathan
Published: May 2021

Suite du discours de l’auteur sur l’état de son pays, si bien gouverné par une reine qu’on peut s’y passer de premier ministre. Portrait d’un pareil ministre.
Chapitre XII
Authors: Swift Jonathan
Published: May 2021

Véracité de l’auteur. Dessein qu’il s’est proposé en publiant cet ouvrage. Il censure ces voyageurs qui n’ont pas un respect inviolable pour la vérité. L’auteur réfute l’accusation qu’on pourrait peut-être lui faire d’avoir eu quelques vues sinistres en écrivant. Réponse à une objection. Méthode de faire des colonies. Éloge de son pays. Il prouve que l’Angleterre a de justes droits sur les pays dont il a fait la description. Difficulté qu’il y aurait à s’en rendre maître. L’auteur prend congé du lecteur, déclare de quelle manière il prétend passer le reste de sa vie, donne un bon avis et finit.
MACHINE-ASSISTED DIAGNOSIS OF CHD BASED ON VARIANT LOGIC THEORY AND MACHINE LEARNING MODELS
Authors: Yao Ruping , Pan Jiahua , Sun Jing , Sun Ke , Wang Weilian
Published: May 2021

Cardiac auscultation is a basic means of initial diagnosis of congenital heart disease (CHD). It is significant to analyze Phonocardiogram (PCG) by using signal processing and machine learning techniques for the purpose of machine-assisted diagnosis of CHD. A novel method of machine-assisted diagnosis of CHD was proposed in this paper. First, the duration of the hidden Markov model (DHMM) was applied to locate and segment PCG into each cardiac cycle. Then, the envelope of the PCG was extracted by using Viola integral. After that, the variant logic theory was applied to extract the features and convert the envelope data of the heart sound signal into visual analysis measurement data. Finally, the classifier of the support vector machine (SVM) was used to classify the normal and abnormal heart sounds. There were 1000 cases used in this study. It was divided into a training set of 600 cases, a test set of 200 cases, and validation set of 200 cases. An accuracy of 0.965, a specificity of 0.898, and a sensitivity of 0.937 were achieved using the novel signal processing techniques. The results showed that DHMM and variant logic theory models were suitable for heart sound classification.
What's on the Docket?
Authors: Schneider Jennifer
Published: May 2021

This chapter describes the design and development of a self-paced, online instructional unit that was designed to provide just-in-time support for students enrolled in legal-studies-related courses (interpreted to include justice studies, criminal justice, and business law coursework). The instructional unit provides an orientation to legal terminology, legal research, and legal writing. The instructional unit also serves as an optional, web-accessible, self-paced orientation. Universal design for learning principles guided the design of the instructional unit as well as all supporting materials and exercises. The chapter presents an overview of how universal design for learning informed and influenced the design and development of the instructional unit. Findings from an associated mixed-methods research study are also shared.
Performance Estimation of Frequency Regulation for a Micro-Grid Power System Using PSO-PID Controller
Authors: Boopathi D. , Saravanan S. , Jagatheesan K. , Anand B.
Published: May 2021

This paper proposes the particle swarm optimization (PSO) technique-based proportional integral derivative (PID) controller suggested for frequency regulation of a micro grid (MG) system. MG system integrates with thermal power generating units, renewable energy sources (RES) like photovoltaic (PV), wind energy generators (WTG), and Energy storage systems (ESS) such as fuel cell (FC) and battery energy storage system (BESS). Indentifying the supremacy of proposed technique-based controller and supremacy is examined with three objective functions (integral absolute error [IAE], integral time absolute error [ITAE], and integral squared error [ISE]). The results of the system are compared with conventional PID controller results. From the comparison, it is clearly evident that PSO-PID controller gives better performance over conventional methods in terms of various time domain specific parameters such as settling time, peak overshoot, and undershoot. In both methods, ITAE objective function used controller produce more effective response in MG under sudden load demand situation.
Structural Mining for Link Prediction Using Various Machine Learning Algorithms
Authors: Behera Ranjan Kumar , Sahoo Kshira Sagar , Naik Debadatt , Rath Santanu Kumar , Sahoo Bibhudatta
Published: May 2021

Link prediction is an emerging research problem in social network analysis, where future possible links are predicted based on the structural or the content information associated with the network. In this paper, various machine learning (ML) techniques have been utilized for predicting the future possible links based on the features extracted from the topological structure. Moreover, feature sets have been prepared by measuring different similarity metrics between all pair of nodes between which no link exists. For predicting the future possible links various supervised ML algorithms like K-NN, MLP, bagging, SVM, decision tree have been implemented. The feature set for each instance in the dataset has been prepared by measuring the similarity index between the non-existence links. The model has been trained to identify the new links which are likely to appear in the future but currently do not exist in the network. Further, the proposed model is validated through various performance metrics.
Prevalence and Predictors of Burnout in Athletic Training Students: A Comparison of Undergraduate and Graduate Students
Authors: Vineyard Ashlyne Paige , Gallucci Andrew , Adair Kathleen , Oglesby Leslie , White Kristina , Wynveen Christopher
Published: May 2021

Context

Burnout is a psychological syndrome consisting of increased emotional exhaustion (EE), depersonalization (DP), and decreased personal accomplishment (PA). To date, examinations of burnout among athletic training students (ATS) is limited.

Objective

To determine prevalence and antecedents of burnout among ATS.

Design

Cross-sectional study.

Setting

Web-based survey.

Patients or Other Participants

Students enrolled in athletic training programs (ATP).

Intervention(s)

A survey assessed demographics, stressors, and burnout measured by the Maslach Burnout Inventory–Human Services Survey.

Main Outcome Measure(s)

Multiple regression analyses were used to determine relationships between variables.

Results

A total of 725 students participated. Most respondents were undergraduates (n = 582, 80%), female (n = 518, 71%), Caucasian (n = 564, 78%), and single (n = 422, 58%). Mean burnout scores for EE, DP, and PA were 33 ± 10, 17 ± 4.5, and 39 ± 5.8, respectively. Survey responses showed that 70.8% of undergraduate and 62.9% of graduate students reported high EE. All the students (100%) in both samples reported high DP. Undergraduates pursuing internships or residencies (b = −7.69, P < .001) and who were currently enrolled in non–Division I institutions (b = −2.90, P < .01) had decreased EE. Increased stress revealed increased EE (overall stress: b = 3.11, P < .001; social stress: b = 1.32, P < .05; class stress: b = 1.45, P < .05). Increases in clinical hours also related to increased EE (b = 1.49, P < .001). Those pursuing internships or residencies (b = −2.10, P < .05) and who were female (b = −2.10, P < .05) reported decreased DP. Being married (b = 2.87, P < .01), increased clinical hours (b = 0.77, P < .001), and social stress (b = 0.59, P < .05) resulted in increased DP. Increased PA was seen in students intending to pursue graduate education (b = 1.76, P < .05) and female students (b = 1.17, P < .05). Graduate students' stress levels revealed increased EE (b = 6.57, P < .01) and DP (b = 0.98, P < .05).

Conclusions

Differences exist between undergraduate and graduate burnout scores and associated predictors. Further research is needed to identify student responses to burnout.
The anatomy of COVID-19 comorbidity networks among hospitalized Korean patients
Authors: Shin Eun Kyong , Choi Hyo Young , Hayes Neil
Published: May 2021

OBJECTIVES: We aimed to examine how comorbidities were associated with outcomes (illness severity or death) among hospitalized patients with coronavirus disease 2019 (COVID-19).METHODS: Data were provided by the National Medical Center of the Korea Disease Control and Prevention Agency. These data included the clinical and epidemiological information of all patients hospitalized with COVID-19 who were discharged on or before April 30, 2020 in Korea. We conducted comorbidity network and multinomial logistic regression analyses to identify risk factors associated with COVID-19 disease severity and mortality. The outcome variable was the clinical severity score (CSS), categorized as mild (oxygen treatment not needed), severe (oxygen treatment needed), or death.RESULTS: In total, 5,771 patients were included. In the fully adjusted model, chronic kidney disease (CKD) (odds ratio [OR], 2.58; 95% confidence interval [CI], 1.19 to 5.61) and chronic obstructive pulmonary disease (COPD) (OR, 3.19; 95% CI, 1.35 to 7.52) were significantly associated with disease severity. CKD (OR, 5.35; 95% CI, 2.00 to 14.31), heart failure (HF) (OR, 3.15; 95% CI, 1.22 to 8.15), malignancy (OR, 3.38; 95% CI, 1.59 to 7.17), dementia (OR, 2.62; 95% CI, 1.45 to 4.72), and diabetes mellitus (OR, 2.26; 95% CI, 1.46 to 3.49) were associated with an increased risk of death. Asthma and hypertension showed statistically insignificant associations with an increased risk of death.CONCLUSIONS: Underlying diseases contribute differently to the severity of COVID-19. To efficiently allocate limited medical resources, underlying comorbidities should be closely monitored, particularly CKD, COPD, and HF.
Histoplasmosis of the Central Nervous System: A Case Series between 1990 and 2019 in French Guiana
Authors: Epelboin Loïc , Dione Aïda , Serris Alexandra , Blanchet Denis , Bidaud Bastien , Walter Gaëlle , Abboud Philippe , Mosnier Emilie , Gaillet Mélanie , Michaud Céline , Couppié Pierre , Demar Magalie , Nacher Mathieu , Djossou Félix , Adenis Antoine
Published: May 2021

Disseminated histoplasmosis is the most frequent acquired immunodeficiency syndrome–defining illness in French Guiana. Paradoxically, central nervous system (CNS) involvement has been scarcely described. We aimed to identify CNS histoplasmosis in our territory. We conducted an observational, multicentric, descriptive, and retrospective study including patients with proven or probable CNS histoplasmosis according to the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MGS). The study population consisted of patients admitted in one of the hospitals of French Guiana between January 1, 1990 and December 31, 2019. During the study period, 390 cases of HIV-associated histoplasmosis were recorded, in which six of them had CNS infections with Histoplasma capsulatum. The male to female sex ratio was 0.25, and the median age at diagnosis was 37.5 years. The median CD4 count was 42 cells/mm3 ([IQR: 29–60]). All patients had disseminated histoplasmosis. Usual signs of meningitis were observed in three patients and focal signs in four patients. One patient had no neurological signs. The median time between the first cerebral symptoms and diagnosis was 22.4 days (IQR 9.5–36.2). Two patients died within a month after diagnosis. In conclusion, few proven CNS localizations of histoplasmosis were observed on 30-year study in French Guiana. This low proportion suggests that the documentation of CNS involvement is often not ascertained for lack of awareness of this particular presentation, and for lack of rapid and sensitive diagnostic tools.
Phytochemical studies of Melilotus officinalis
Authors: A. Sisay M. , Mammo W. , E. Yaya E.
Published: May 2021

GC-MS analysis of the n-hexane extract of Melilotus officinalis seeds revealed twelve compounds with a combined area percentage of 98.33% predominantly, (9Z,12Z)-octadecadienoic acid (20.22%, 366 ppm), 14-methylpentadecanoic acid (19.52%, 353 ppm) and (9E)-octadecenoic acid (15.94%, 289 ppm). Two compounds, namely, cis-coumaric acid-2-O-β-D-glucopyranoside (cis-melilotoside, 1) and 1,2-benzopyrone (coumarin, 2), were isolated from the MeOH extract of the seeds of M. officinalis. The structures of isolated compounds were determined by spectroscopic techniques such as NMR, UV-Vis, and FTIR. The MeOH extract of M. Officinalis was also tested for its antioxidant activity using DPPH assay. The extract showed 29.87% DPPH inhibition at concentration of 100 μg/mL.

                   

KEY WORDS: Melilotus officinalis, Fatty acid methyl esters, Esterification, GC-MS, DPPH radical scavenging assay, Antioxidant activity

 

Bull. Chem. Soc. Ethiop. 2021, 35(1), 141-150.

DOI: https://dx.doi.org/10.4314/bcse.v35i1.12
Cognitive profile in anti-NMDAR encephalitis: Neuropsychological evaluation, rehabilitation, and evolution. A case report
Authors: Montoro-Membila Nuria , Gómez-Camello Angel , Villegas-Rodríguez Inmaculada , Triviño-Mosquera Mónica
Published: May 2021

Encephalitis associated with antibodies against the N-methyl-D-aspartate receptor (i.e., anti-NMDAR encephalitis) is an immune-mediated disorder mainly affecting girls and young women with ovarian teratoma. The clinical picture of the disease progresses from headaches and seizures, psychopathological symptoms (i.e., anxiety, psychosis, or hyperreligiosity), and neuropsychological deficits (i.e., memory, attention, and language disintegration) into a state of agitation, catatonia, dysautonomia (i.e., abnormal movements due to inappropriate muscular activity) and facial dyskinesia. Reports of the neuropsychological profile and evolution, as well as the neuropsychological rehabilitation in anti-NMDAR encephalitis in the literature are scarce. We present the case of a 21-year-old woman diagnosed with anti-NMDAR encephalitis and we describe the different neuropsychological evaluation tests performed before and after neuropsychological rehabilitation during the acute period. A profile of fronto-subcortical neuropsychological damage was observed, with executive functions and emotional regulation affected.
Impact of Coronavirus Lockdown among the Seventh - day Adventist Community Members in Masvingo Urban, Zimbabwe
Authors: Manungo Rodgers , Rukuni Tinashe
Published: May 2021

This study sought to establish the financial, spiritual and social impact of the Coronavirus lockdown among the Seventh-day Adventist community members in Masvingo Urban, Zimbabwe. The study focused on how the households, the informally employed parents and students perceived their financial, spiritual and social status during the lockdown, especially pertaining to the positives and negatives that might have emanated from the period. The study employed the participant oriented interpretive phenomenological approach, which allowed the respondents to share their lived experiences during the period. The four SDA districts in Masvingo have about 4000 members who were all given a chance to participate in the study. From these, 35 members who comprised 20 males and 15 females of between 16 and above 55 years, from the parent and student categories returned the questionnaire within the stipulated two week period directly to the researchers and via their pastors. Collected data was coded according to the financial, spiritual, and social experiences, which were further divided into subthemes. Key findings revealed that members of the church, who were involved in the formal and informal sectors of the economy, were financially affected during the lockdown. Some members were spiritually affected, due to boredom; hence some broke the Sabbath regulations. Some found the alternative radio, television and online Christian programs spiritually uplifting, though. Socially, members were affected by the inter-provincial, inter-district and national border restrictions imposed at the time. Evidently, some members took the time to bond with their immediate family. The study recommends that there be plans in place to address the financial and physical needs of the members on the part of the government and the private sector, including the church during lockdowns; such plans should also include effective distribution methods of these resources to the households. Further, the church needs to introduce more radio and television programs.
EFFECT OF DIETARY METHIONINE ON GROWTH AND UTILIZATION OF CLARIAS GARIEPENIUS FINGERLINGS
Authors:   Department of Fisheries, University of Benin, Benin-City, Nigeria., Aliu BS , Omenogor SO ,   Department of Fisheries, University of Benin, Benin-City, Nigeria.
Published: May 2021

The growth response and feed utilization of Clarias gariepinus fed with diet containing different level of dietary synthetic methionine was investigated to determine the effect of diet on their growth rate and its utilization by fish. (108) fingerlings of Calrias gariepinus (2.1+0.5g) obtained from a private fish farm in Benin City were stocked in eighteen (18) 25L plastic tank. 6 diet (40%) crude protein consisting of a control (0% methionine supplementation) and five DIT other diet (3.2%, 4.23%, 7.30%, 8.70% and 9.79% synthetic methionine supplementation) were compounded and fed to the fish till satiation. Each diet was fed to the fish twice daily (9.00hrs and 17.00hrs). Data on the weight gain and feed consumed were taken on weekly basis. There was no significant difference in term of relative weight gain (RWG), specific growth rate (SGR), total weight gain (TWG) and weekly weight gain (WWG). The control with (0% methionine) showed a higher weight gain with diet 5 (8.76% methionine) having a lower weight gain. However, the feed intake (FI) was significantly different (P<0.005) with the control midway the highest feed intake but diet 2 (4.25%) with a step downward showed lowest feed intake. The protein efficiency ratio (per) value were significantly different with diet 1 having the highest value which was different from all other which with diet 4 having a lowest per. In terms of survival there was significant difference (P<0.05) with diet 3(0% methionine). Supplementation has the highest and a reduced survival at diet 2 synthetic methionine. In this study synthetic methionine had not been sufficiently utilized by Clarias gariepinus fingerling since the control did perform better than those supplemented with various level of methionine.
Impact of Environmental Design in Interception of Crime
Authors:   Student, Amity School of Architecture and Planning, Amity University Chhattisgarh, Goyal Nancy
Published: May 2021

Crime has become one among the most important issues in cities round the world. This issue has given rise to varied issues in terms of worry of crime and has become a significant disturbance for residents in urban areas. Crimes like devastation, terrorism, burglary, shoplifting, employee theft, assault, and espionage endanger lives and threaten the built environment. This has subsequently led to the need for crime prevention action to be taken. Architectural and urban designs that take into account safety from crime, and security against criminal damage or terrorism is what termed as security designs, which mainly focuses on the specific element of security and crime prevention that relates to the physical opportunity for victimization, damage and harm. By improving environmental design, it can be prevented to some extent. This paper includes the outline of ways like, crime prevention through environmental design (CPTED), defensible space, and building security. This paper also includes about the creating of safe cities, safe work environments, and safe places to live and play. The main aim of this paper is to know how the crime prevention methods could be linked more closely to developments in architecture and design. This approach to a security design recognizes the intended use of space in building and is totally different from traditional security practice, which focuses on denying access to a crime target with barrier techniques.
The Colour Perception – In an Indoor & Outdoor Architectural Environment
Authors:   Student 10th Semester, Amity School of Architecture and Planning, Amity University Chhattisgarh, Lahoti Radhika
Published: May 2021

Colour is considered an integral element for an indoor and outdoor environment. It is an essential element of our environmental experience and visual perception. It is often connected to, stimulated by, light in the natural or human design environment and accompanies us in different visible ways. They are the substance of how we experience the surroundings, as humans are the centre of concern in designing the architectural environment. It affects individuals differently based upon their age, gender, culture and other biological factors. Colour is a universal visual language appreciated by all. The aim is to utilise colour as an expressive component to emphasise the building character and create unity and harmony.
Formation of Reproductive Behavior of Student Youth in the Process of Studying the Humanities
Authors:   Doctor of Philosophy in Pedagogical Sciences (PhD), Senior Lecturer, Department of “Methods of teaching languages” Regional Center for Retraining and Advanced Training of Public  Education Staff of Surkhandarya region, Kenjaboeva Nigora Mamayusufovna
Published: May 2021

This article addresses issues scientific analysis of state policy on the education of the reproductive culture of youth, the practical state of the development of the reproductive culture of students, scientific and pedagogical conditions for the development of the reproductive culture of students, information about the organization and conduct of the development of the reproductive culture of students.
Knowledge as a Source of Innovation for Entrepreneurial Firms
Authors:   Universiti Teknologi Brunei, Janaji Siti Aisah
Published: May 2021

Knowledge is perceived as critical sources to non-technological and technological entrepreneurial firms in commercializing products and services. Knowledge-based view highlights that the diverse knowledge bases within firms reflect the firms’ performance. Gradually, the access to external and internal sources of knowledge can be transformed into stocks of knowledge thus, is embedded in such as organizational routines. Albeit the fact that entrepreneurial firms may have lack of financial capital, the exploration and exploitation of new and existing knowledge will enable firms to create value, and subsequently obtain competitive advantage as they grow. This paper will review how entrepreneurial firms can utilize knowledge for innovation.