bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Softeners Applications on Moisture Management Properties of Polyester/Cotton Blended Sandwich Weft-Knitted Fabric Structure
Authors: Siddique Amna , Hassan Tufail , Abid Sharjeel , Ashraf Munir , Hussain Azmat , Shafiq Faizan , Khan Muhammad Qamar , Kim Ick Soo
Published: May 2021

Prolonged drying times of terry fabrics is a problem as they can not be re-used until completely dry. To resolve this issue, we have designed a sandwich polyester in the mid-layer with low moisture content that could reduce the drying time with excellent wicking properties. These fabrics are widely used as activewear and sportswear. The effect of different softeners on the moisture management properties of weft-knitted terry fabrics’ for various applications has also been studied. Terry knitted fabrics were prepared using a circular knitting machine. Six different softeners were applied with three different concentrations, i.e., 10 g/L, 15 g/L, and 20 g/L, on the fabric using the pad-dry-cure method. Moisture management tests and rubbing fastness tests were performed to analyze the applied softener’s effect on the fabric comfort and moisture management performance. Results revealed that softener type (i.e., cationic, anionic, and non-ionic) and concentration levels considerably affect the moisture management capability of terry knitted fabrics.
Effect of Thicknesses of Liquid Crystal Layers on Shift of Resonance Frequencies of Metamaterials
Authors: Chiang Wei-Fan , Lin Shih-Xuan , Lee Yong-Xuan , Shih Yu-Han , Liu Jih-Hsin , Silalahi Harry-Miyosi , Lee Chia-Rong , Huang Chia-Yi
Published: May 2021

A liquid crystal (LC) layer that is too thick exhibits a small terahertz birefringence due to the limited long-range force of the alignment layers that exert on it. An LC layer that is too thin has a small terahertz birefringence due to its invisibility to incident terahertz waves. Therefore, an LC layer may have a large terahertz birefringence at a specific thickness. It is well known that the birefringence of an LC layer dominates the shift of the resonance frequency of the metamaterial imbedded into the LC layer. As a result, this work studies the effect of the thicknesses of LC layers on the shift of the resonance frequencies of metamaterials. LC layers with various thicknesses ranging from 310 µm to 1487 µm are deposited on terahertz metamaterials, and each of the layers is aligned by two polyimide layers that are rubbed in a direction. The terahertz metamaterials have a maximum frequency shifting range of 21 GHz as 710 µm thick LC layers with mutually orthogonal rubbing directions are deposited on them. The maximum frequency shifting range arises from the competition between the long-range force of the polyimide layers and the interaction between the LC layers and their incident terahertz waves.
Effect of Ion Energy on the Microstructure and Properties of Titanium Nitride Thin Films Deposited by High Power Pulsed Magnetron Sputtering
Authors: Ma Donglin , Deng Qiaoyuan , Liu Huaiyuan , Leng Yongxiang
Published: May 2021

Titanium nitride (Ti-N) thin films are electrically and thermally conductive and have high hardness and corrosion resistance. Dense and defect-free Ti-N thin films have been widely used in the surface modification of cutting tools, wear resistance components, medical implantation devices, and microelectronics. In this study, Ti-N thin films were deposited by high power pulsed magnetron sputtering (HPPMS) and their plasma characteristics were analyzed. The ion energy of Ti species was varied by adjusting the substrate bias voltage, and its effect on the microstructure, residual stress, and adhesion of the thin films were studied. The results show that after the introduction of nitrogen gas, a Ti-N compound layer was formed on the surface of the Ti target, which resulted in an increase in the Ti target discharge peak power. In addition, the total flux of the Ti species decreased, and the ratio of the Ti ions increased. The Ti-N thin film deposited by HPPMS was dense and defect-free. When the energy of the Ti ions was increased, the grain size and surface roughness of the Ti-N film decreased, the residual stress increased, and the adhesion strength of the Ti-N thin film decreased.
Synthesis of Highly Luminescent InP/ZnS Quantum Dots with Suppressed Thermal Quenching
Authors: Lian Linyuan , Li Youyou , Zhang Daoli , Zhang Jianbing
Published: May 2021

InP quantum dots (QDs) are promising down-conversion phosphors for white light LEDs. However, the mainstream InP QDs synthesis uses expensive phosphorus source. Here, economic, in situ-generated PH3 is used to synthesize InP QDs and a two-step coating of ZnS shells is developed to prepare highly luminescent InP/ZnS/ZnS QDs. The QDs show a photoluminescence quantum yield as high as 78.5%. The emission can be tuned by adjusting the halide precursor and yellow emissive InP/ZnS/ZnS QDs are prepared by judiciously controlling the synthetic conditions. The yellow QDs show suppressed thermal quenching and retain >90% room temperature PL intensity at 150 °C for the growth solution. Additionally, the PL spectrum matches with the eye sensitivity function, resulting in efficient InP QD white light LEDs.
Guiding Stem Cell Differentiation and Proliferation Activities Based on Nanometer-Thick Functionalized Poly-p-xylylene Coatings
Authors: Wu Chih-Yu , Chiang Yu-Chih , Christy Jane , Huang Abel Po-Hao , Chang Nai-Yun , Wenny  , Chiu Yu-Chih , Yang Yen-Ching , Chen Po-Chun , Wang Peng-Yuan , Chen Hsien-Yeh
Published: May 2021

Modifications of biomaterials based on the combination of physical, chemical, and biological cues for manipulating stem cell growth are needed for modern regenerative medicine. The exploitation of these sophisticated modifications remains a challenge, including substrate limitation, biocompatibility, and versatile and general cues for stem cell activities. In this report, a vapor-phase coating technique based on the functionalization of poly-p-xylylene (PPX) was used to generate a surface modification for use with stem cells in culture. The coating provided the ability for covalent conjugation that immobilized bone morphogenetic protein 2 (BMP-2) and fibroblast growth factor 2 (FGF-2), and the modified coating surfaces enabled direct stem cell differentiation and controlled proliferation because of the specific activities. The ligations were realized between the growth factors and the maleimide-modified surface, and the conjugation reactions proceeded with high specificity and rapid kinetics under mild conditions. The conjugation densities were approximately 140 ng·cm−2 for BMP-2 and 155 ng·cm−2 for FGF-2. Guiding the activities of the human adipose-derived stem cells (hADSCs) was achieved by modifying surfaces to promote the hADSC differentiation capacity and proliferation rate. The reported coating system demonstrated biocompatibility, substrate-independent conformity, and stability, and it could provide an effective and versatile interface platform for further use in biomedical applications.
Research on Thermal Stability and Properties of Ca3ZrSi2O9 as Potential T/EBC Materials
Authors: Pan Yangyang , Liang Bo , Niu Yaran , Han Dijuan , Liu Dongdong , Zheng Xuebin
Published: May 2021

In this study, a new coating material for thermal barrier coating (TBC) or environment barrier coating (EBC) application, Ca3ZrSi2O9 (CZSO), was synthesized and prepared by atmospheric plasma spray (APS) technology. The evolution of the phases and microstructures of the coatings with different thermal-aged were characterized by XRD, XRF, EDS and SEM, respectively. The thermal stability was measured by TG-DTA and DSC. The mechanical and thermal properties, including Vickers hardness (HV), fracture toughness (KIC), thermal conductivity (κ) and coefficient of thermal expansion (CTE) were focused on. It was found that the as-sprayed CZSO coating contained amorphous phase. Crystalline transformation happened at 900–960 °C and no mass changes took place from room temperature (RT) to 1300 °C. The phenomena of microcrack self-healing and composition uniformity were observed during thermal aging. The κ of coating was very low at about 0.57–0.80 W·m−1·K−1 in 200–1200 °C. The combined properties indicated that the CZSO coating might be a potential T/EBC material.
The Investigation of Indium-Free Amorphous Zn-Al-Sn-O Thin Film Transistor Prepared by Magnetron Sputtering
Authors: Zhang Mingyu , Lu Kuankuan , Xu Zhuohui , Ning Honglong , Zhang Xiaochen , Chen Junlong , Yang Zhao , Zeng Xuan , Yao Rihui , Peng Junbiao
Published: May 2021

The indium-free amorphous oxide semiconductor thin film transistor (AOS-TFT) with aluminum (Al) electrodes shows broad application prospects in new-generation display technologies, such as ultra-high definition large-screen display, OLED display and 3D display. In this work, the thin film transistor (TFT) with a zinc-aluminum-tin-oxide (ZATO) semiconductor as the active layer and an Al electrodes as the source and drain (S/D) was investigated. The optical, electrical and semiconductive properties of the ZATO films were evaluated by atomic force microscopy (AFM), ultraviolet–visible spectrophotometry and microwave photoconductivity decay (μ-PCD), respectively. The result shows that the film is smooth and transparent and has low localized states and defects at a moderate oxygen concentration (~5%) and a low sputtering gas pressure (~3 mTorr). After the analysis of the transfer and output characteristics, it can be concluded that the device exhibits an optimal performance at the 623 K annealing temperature with an Ion/Ioff ratio of 5.5 × 107, an SS value of 0.15 V/decade and a saturation mobility (μsat) of 3.73 cm2·V−1·s−1. The ZATO TFT at the 623 K annealing has a −8.01 V negative shift under the −20 V NBS and a 2.66 V positive shift under the 20 V PBS.
Pseudo-Planar Organic Heterojunctions by Sequential Printing of Quasi-Miscible Inks
Authors: Gereanu Ana-Gianina , Sartorio Camillo , Bonasera Aurelio , Giuliano Giuliana , Cataldo Sebastiano , Scopelliti Michelangelo , Arrabito Giuseppe , Pignataro Bruno
Published: May 2021

This work deals with the interfacial mixing mechanism of picoliter (pL)-scale droplets produced by sequential inkjet printing of organic-based inks onto ITO/PET surfaces at a moderately high Weber number (~101). Differently from solution dispensing processes at a high Bond number such as spin coating, the deposition by inkjet printing is strictly controlled by droplet velocity, ink viscosity, and surface tension. In particular, this study considers the interfacial mixing of droplets containing the most investigated donor/acceptor couple for organic solar cells, i.e., poly(3-hexylthiophene) (P3HT) and (6,6)-phenyl-C61-butyric acid methyl ester (PCBM), showing how low-viscosity and low-surface energy inks can be leveraged for the fabrication of an interface suitable for a pseudo-planar heterojunction (pseudo-PHJ) organic solar cell (OSC) that is a convenient alternative to a bulk heterojunction (BHJ) OSC. The resulting thin-film morphology and molecular organization at the P3HT/PCBM interface are investigated, highlighting the roles of dissolution-driven molecular recirculation. This report represents a first step toward the sequential inkjet printing fabrication of pseudo-PHJ OSCs at low consumption of solvents/chemicals.
Halo Blight of Mungbean in Australia
Authors: Abdullah Araz Sedqi , Douglas Col
Published: May 2021

Halo blight, one of the major diseases of mungbean, is caused by the bacterium Pseudomonas savastanoi pv. phaseolicola. The pathogen infects the foliar parts of the plant, causing water-soaked spots that eventually develop surrounding yellow margins. The disease is particularly destructive under moderate temperature and high humidity, especially when it occurs during late vegetative through to early reproductive stage. In such conditions, severely infected crops could experience a yield loss up to 70%. Halo blight can be widespread on mungbeans grown in Southern Queensland and Northern New South Wales. However, due to its seedborne and cryptic nature of transmission, the disease is likely to be under-reported. This report addresses major aspects of halo blight symptomology, pathology and epidemiology.
Chemical Composition of Apples Cultivated in Norway
Authors: Wicklund Trude , Guyot Sylvain , Le Quéré Jean-Michel
Published: May 2021

The composition of apples varies with both cultivar and horticultural practice. Knowledge about the chemical composition of different cultivars in particular sugars, organic acids, nitrogen compounds and polyphenols is essential, since they are directly related to the progress of fermentation monitoring and the organoleptic qualities of produced ciders. Fifteen apple cultivars grown in two locations in Norway were investigated for their chemical composition, including polyphenol profiles. The nitrogen content varied from 43.2 to 171.4 mg N/L between the cultivars, and the sum of free amino acids varied from 42.4 to 924.5 mg/kg. Asparagine, aspartic acid and glutamic acid were the dominating amino acids. Flavanols, consisting of catechins and procyanidins, were the dominating polyphenols, followed by hydroxycinnamic acids. The cultivar Bramley Seedling was highest in the sum of polyphenols by HPLC (1838 mg/L) and relatively low in nitrogen content (75 mg N/L). Summerred was lowest in the sum of polyphenols (87 mg/L) and highest in nitrogen (171.4 mg N/L). Sugar content, measured as density in the juice, varied between 1034 and 1060 g/L. Using cider categorization of apples, ’Bramley Seedling’ would be defined as sharp, while the others are sweet cultivars.
Synthesis, Thermal and Optical Characterizations of New Lateral Organic Systems
Authors: Al-Mutabagani Laila Ahmed. , Alshabanah Latifah A. , Gomha Sobhi M. , Ahmed Hoda A.
Published: May 2021

New laterally OCH3-substituted optical organic Schiff base/ester series, namely 4-(4-(hexyloxyphenyl)iminomethyl)-3-methoxyphenyl 4-alkoxybenzoates, were prepared and characterized with different thermal, mesomorphic, and photoactive techniques. The prepared group constitutes five homologues that differ from each other in the number of carbons in the terminal alkoxy chain (n), which varies between n = 6, 8, 10, 12, and 16 carbons. The laterally protruded methoxy group is attached to the central benzene ring that makes an angle of 120° with the molecular long axis. Molecular structures of all newly prepared homologues were fully elucidated via FT-IR, 1H and 13C NMR spectroscopy. Mesomorphic transitions were determined via differential scanning calorimetry (DSC) and the phases identified by polarized optical microscopy (POM). Independent of the length of the terminal alkoxy chain attached to phenyl ester ring, only a monomorphic nematic (N) phase was observed for all the synthesized compounds. A comparative study was made between the present lateral methoxy-substituted homologues and their corresponding laterally-neat analogues. The results revealed that, depending on the length of the alkoxy chain and the presence or absence of the lateral methoxy group, different mesophases with different thermal stability and temperature ranges were observed. Finally, UV-vis spectra showed that the present nematogenic series possess photoactive properties that are of importance for many applications.
Experimental Evaluation of Cement Mortars with End-of-Life Tyres Exposed to Different Surface Treatments
Authors: García Eduardo , Villa Bárbara , Pradena Mauricio , Urbano Bruno , Campos-Requena Víctor H. , Medina Carlos , Flores Paulo
Published: May 2021

An end-of-Life Tyre (ELT) is a type of waste that can generate negative social and environmental impacts due to its disposal. Considering that rubber can improve concrete properties and the massive use of concrete as construction material, the addition of ELT rubber in concrete mixes is attractive. However, concrete mechanical properties are negatively affected due to the rubber-cementitious matrix interaction. Although rubber treatments have been developed to minimise the negative effects, the geo-dependency of the mix makes necessary to find cost-effective and practical solutions that will allow a real use of the ELT waste. Therefore, the objective of the present study is to characterise the properties of cement mortars with the addition of ELT rubber under three surface treatments: hydration, oxidation-sulphonation, and hydrogen peroxide. The results show that hydration is the most favourable treatment from a technical, practical, and economical point of view. In fact, with this treatment, it is possible to add up to 5% ELT rubber, with respect to the aggregate weight, and still exceed the design strength without adding more cement or additives as other investigations. The use of Portland Pozzolana Cement, with local fly ash waste, contributes as well to the promissory results obtained.
Investigation of the Wear Behavior of Surface Welding AZ91 and AZ91+Gd Alloys under Variable Loading Conditions
Authors: Chen Qingqiang , Yu Yalei , Sun Jie , Jing Cainian , Zhao Yanhua , Wang Jia
Published: May 2021

Adding rare earth elements to magnesium alloys is an effective way to improve their wear resistance. However, the effect achieved is closely related to the friction condition. In this paper, two different types of welding wires, AZ91 magnesium alloy and AZ91 + gadolinium (Gd), were used for surface welding. Dry sliding friction and wear experiments were performed on the surfacing alloys using the pin-on-disc test. The effects of Gd addition on the wear resistance and wear mechanism of the alloy were systematically studied under low to high loads. The results show that as the load increases, the friction coefficient of the surfacing AZ91 alloy gradually decreases as the wear rate increases. A mild–severe wear transition occurred at 100 N. The addition of Gd only slightly increased the wear rate under a load of 15 N. The wear rate was significantly decreased with loads in the range of 30 to 100 N and mild–severe wear transition was avoided. The influence of both Gd addition and load on the wear mechanism were considered. The overall wear resistance of the surfacing magnesium alloy was determined.
Enhanced Electrostrictive Coefficient and Suppressive Hysteresis in Lead-Free Ba(1−x)SrxTiO3 Piezoelectric Ceramics with High Strain
Authors: Song Mu , Sun Xiaoyuan , Li Qiong , Qian Hao , Liu Yunfei , Lyu Yinong
Published: May 2021

Lead-free piezoelectric ceramics with both low hysteresis and superior electrostrictive coefficient features are crucial toward providing desired performance for intelligent electrical devices, especially in high-precision displacement actuators. In this work, we propose a novel scenario, which is to design the phase transition around ambient temperature to enhance electrostrictive effect and inhibit hysteresis. In other words, the dense ceramics with cubic phases (C) and tetragonal phases (T) coexisting at RT (room temperature) were designed. According to this scenario, the Ba(1−x)SrxTiO3 (abbreviated as BT-100xST) ceramics were fabricated by the conventional solid-state reaction method. The relaxor behavior, ferroelectric properties, crystal structure and microstructure of BT-100xST ceramics have been investigated in detail. As a result, the BT-100xST ceramics with x = 0.20–0.40 present relaxor behavior which was indicated by dielectric constant as a function of temperature and (polarization–electric field) P–E hysteresis loops. The BT-30ST ceramics exhibit enhanced electrostrictive coefficient Q33 (>0.034 m4/C2), and the electrostrictive strain and low hysteresis achieves 0.11% and 2%, respectively. The BT-100xST ceramics are considered as a prospective option for application in displacement actuators with high sensitivity and high precision.
Study on Microstructure and Properties of 12Ag–Cu–Zn–Sn Cadmium-Free Filler Metals with Trace In Addition
Authors: Wu Jie , Xue Songbai , Yao Zhen , Long Weimin
Published: May 2021

The effect of different In contents on the melting characteristics, mechanical properties, and microstructure of 12Ag–Cu–Zn–Sn filler metal was investigated in this paper, and flame brazing of 304 stainless steel and copper plates was done using the 12Ag–Cu–Zn–Sn–xIn filler metal. The results indicate that adding appropriate amount of In can evidently decrease the solidus and liquidus temperatures and improve the wettability of the low silver based filler metals. In addition, the shear strength of 304 stainless steel and copper plates joint brazed by 12Ag–Cu–Zn–Sn–1In are satisfactory due to the solution strength effect, and scanning electron microscopy examination of the braze-zone revealed that more relatively sound joints were obtained when brazing was done with 12Ag–Cu–Zn–Sn–xIn filler metal than with Indium free one; its performance is comparable to that of the joint brazed with the 20Ag–Cu–Zn–Sn filler metal, having a remarkable silver-saving effect.
Advancing Amphibian Conservation through Citizen Science in Urban Municipalities
Authors: Lee Tracy S. , Kahal Nicole L. , Kinas Holly L. , Randall Lea A. , Baker Tyne M. , Carney Vanessa A. , Kendell Kris , Sanderson Ken , Duke Danah
Published: May 2021

As cities adopt mandates to protect, maintain and restore urban biodiversity, the need for urban ecology studies grows. Species-specific information on the effects of urbanization is often a limiting factor in designing and implementing effective biodiversity strategies. In suburban and exurban areas, amphibians play an important social-ecological role between people and their environment and contribute to ecosystem health. Amphibians are vulnerable to threats and imbalances in the aquatic and terrestrial environment due to a biphasic lifestyle, making them excellent indicators of local environmental health. We developed a citizen science program to systematically monitor amphibians in a large city in Alberta, Canada, where 90% of pre-settlement wetlands have been removed and human activities continue to degrade, alter, and/or fragment remaining amphibian habitats. We demonstrate successes and challenges of using publicly collected data in biodiversity monitoring. Through amphibian monitoring, we show how a citizen science program improved ecological knowledge, engaged the public in urban biodiversity monitoring and improved urban design and planning for biodiversity. We outline lessons learned to inform citizen science program design, including the importance of early engagement of decision makers, quality control assessment, assessing tensions in program design for data and public engagement goals, and incorporating conservation messaging into programming.
Linking Habitat and Associated Abiotic Conditions to Predict Fish Hotspots Distribution Areas within La Paz Bay: Evaluating Marine Conservation Areas
Authors: Urcádiz-Cázares Francisco Javier , Cruz-Escalona Víctor Hugo , Peterson Mark S. , Aguilar-Medrano Rosalía , Marín-Enríquez Emigdio , González-Peláez Sergio Scarry , Del Pino-Machado Arturo , Enríquez-García Arturo Bell , Borges-Souza José Manuel , Ortega-Rubio Alfredo
Published: May 2021

Hotspots are priority marine or terrestrial areas with high biodiversity where delineation is essential for conservation, but equally important is their linkage to the environmental policies of the overall region. In this study, fish diversity presences were linked to abiotic conditions and different habitat types to reveal multi-species and hotspots models predicted by ecological niche modelling methods within the Bay of La Paz, Mexico (south of Gulf of California). The abiotically suitable areas for 217 fish species were identified based on historical (1975–2020) presence data sets and a set of environmental layers related to distances from mangroves and rocky shores habitats, marine substrate, and bottom geomorphology conditions. Hotspot model distribution was delineated from a multi-species model identifying areas with ≥60 species per hectare and was compared to the marine conservation areas such Balandra Protected Natural Area (BPNA), illustrating how these models can be applied to improve the local regulatory framework. The results indicate that (1) there is a need for the BPNA to be enlarged to capture more of the delineated hotspot areas, and thus an update to the management plan will be required, (2) new conservation areas either adjacent or outside of the established BPNA should be established, or (3) Ramsar sites or other priority areas should be subject to legal recognition and a management plan decreed so that these vital habitats and fish diversity can be better protected.
Automated Assessment of Thoracic-Abdominal Asynchrony in Patients with Morquio Syndrome
Authors: Ratnagiri Madhavi V. , Zhu Yan , Rahman Tariq , Theroux Mary , Tomatsu Shunji , Shaffer Thomas H.
Published: May 2021

Morquio syndrome is a rare disease caused by a disorder in the storage of mucopolysaccharides that affects multiple organs, including musculoskeletal, respiratory, cardiovascular, and digestive systems. Respiratory failure is one of the leading causes of mortality in Morquio patients; thus, respiratory function testing is vital to the management of the disease. An automated respiratory assessment methodology using the pneuRIP device and a machine-learning algorithm was developed. pneuRIP is a noninvasive approach that uses differences between thoracic and abdominal movements (thoracic-abdominal asynchrony) during respiration to assess respiratory status. The technique was evaluated on 17 patients with Morquio (9 females and 8 males) between the ages of 2 and 57 years. The results of the automated technique agreed with the clinical assessment in 16 out of the 17 patients. It was found that the inverse cumulative percentage representation of the time delay between the thorax and abdomen was the most critical variable for accurate evaluation. It was demonstrated that the technique could be successfully used on patients with Morquio who have difficulty breathing with 100% compliance. This technique is highly accurate, portable, noninvasive, and easy to administer, making it suitable for a variety of settings, such as outpatient clinics, at home, and emergency rooms.
Past, Present, and Future of Blood Biomarkers for the Diagnosis of Acute Myocardial Infarction—Promises and Challenges
Authors: Tilea Ioan , Varga Andreea , Serban Razvan Constantin
Published: May 2021

Despite important advancements in acute myocardial infarction (AMI) management, it continues to represent a leading cause of mortality worldwide. Fast and reliable AMI diagnosis can significantly reduce mortality in this high-risk population. Diagnosis of AMI has relied on biomarker evaluation for more than 50 years. The upturn of high-sensitivity cardiac troponin testing provided extremely sensitive means to detect cardiac myocyte necrosis, but this increased sensitivity came at the cost of a decrease in diagnostic specificity. In addition, although cardiac troponins increase relatively early after the onset of AMI, they still leave a time gap between the onset of myocardial ischemia and our ability to detect it, thus precluding very early management of AMI. Newer biomarkers detected in processes such as inflammation, neurohormonal activation, or myocardial stress occur much earlier than myocyte necrosis and the diagnostic rise of cardiac troponins, allowing us to expand biomarker research in these areas. Increased understanding of the complex AMI pathophysiology has spurred the search of new biomarkers that could overcome these shortcomings, whereas multi-omic and multi-biomarker approaches promise to be game changers in AMI biomarker assessment. In this review, we discuss the evolution, current application, and emerging blood biomarkers for the diagnosis of AMI; we address their advantages and promises to improve patient care, as well as their challenges, limitations, and technical and diagnostic pitfalls. Questions that remain to be answered and hotspots for future research are also emphasized.
Sudden Death without a Clear Cause after Comprehensive Investigation: An Example of Forensic Approach to Atypical/Uncertain Findings
Authors: Grassi Simone , Vidal Mònica Coll , Campuzano Oscar , Arena Vincenzo , Alfonsetti Alessandro , Rossi Sabina Strano , Scarnicci Francesca , Iglesias Anna , Brugada Ramon , Oliva Antonio
Published: May 2021

Sudden death (SD) is defined as the unexpected natural death occurred within an hour after the onset of symptoms or from the last moment the subject has been seen in a healthy condition. Brugada syndrome (BrS) is one of the most remarkable cardiac causes of SD among young people. We report the case of a 20-year-old man who suddenly died after reportedly having smoked cannabis. Autopsy, toxicology, and genetic testing were performed. Autopsy found a long and thick myocardial bridging (MB) at 2 cm from the beginning of the left anterior descending coronary artery. Furthermore, at the histopathological examination, fibrosis and disarray in myocardial area above the MB, fatty tissue in the right ventricle and fibrosis of the sino-atrial node area were found. Toxicology testing was inconclusive, while genetic testing found a rare missense variant of the TTN gene, classified as likely benign, and a variant of unknown significance in the SLMAP gene (a gene that can be associated with BrS). Hence, despite several atypical features were found, no inference on the cause of the death could be made under current evidence.
Understanding False Negative in Prenatal Testing
Authors: Evans Mark I. , Chen Ming , Britt David W.
Published: May 2021

A false negative can happen in many kinds of medical tests, regardless of whether they are screening or diagnostic in nature. However, it inevitably poses serious concerns especially in a prenatal setting because its sequelae can mark the birth of an affected child beyond expectation. False negatives are not a new thing because of emerging new tests in the field of reproductive, especially prenatal, genetics but has occurred throughout the evolution of prenatal screening and diagnosis programs. In this paper we aim to discuss the basic differences between screening and diagnosis, the trade-offs and the choices, and also shed light on the crucial points clinicians need to know and be aware of so that a quality service can be provided in a coherent and sensible way to patients so that vital issues related to a false negative result can be appropriately comprehended by all parties.
Short-Term CPAP Improves Biventricular Function in Patients with Moderate-Severe OSA and Cardiometabolic Comorbidities
Authors: Zota Ioana Mădălina , Sascău Radu Andy , Stătescu Cristian , Tinică Grigore , Leon Constantin Maria Magdalena , Roca Mihai , Boișteanu Daniela , Anghel Larisa , Mitu Ovidiu , Mitu Florin
Published: May 2021

Obstructive sleep apnea (OSA) is the most common form of sleep-disordered breathing, exhibiting an increasing prevalence and several cardiovascular complications. Continuous positive airway pressure (CPAP) is the gold-standard treatment for moderate-severe OSA, but it is associated with poor patient adherence. We performed a prospective study that included 57 patients with newly diagnosed moderate-severe OSA, prior to CPAP initiation. The objective of our study was to assess the impact of short-term CPAP on ventricular function in patients with moderate-severe OSA and cardiometabolic comorbidities. The patients underwent a clinical exam, ambulatory blood pressure monitoring and comprehensive echocardiographic assessment at baseline and after 8 weeks of CPAP. Hypertension, obesity and diabetes were highly prevalent among patients with moderate-severe OSA. Baseline echocardiographic parameters did not significantly differ between patients with moderate and severe OSA. Short-term CPAP improved left ventricular global longitudinal strain (LV-GLS), isovolumetric relaxation time, transmitral E wave amplitude, transmitral E/A ratio, right ventricular (RV) diameter, RV wall thickness, RV systolic excursion velocity (RV S‘) and tricuspid annular plane systolic excursion (TAPSE). Short-term CPAP improves biventricular function, especially the LV-GLS, which is a more sensitive marker of CPAP-induced changes in LV systolic function, compared to LVEF. All these benefits are dependent on CPAP adherence.
Serological and Molecular Evidence of Patients Infected with Anaplasma phagocytophilum in Mexico
Authors: Sosa-Gutierrez Carolina Guadalupe , Cervantes-Castillo Maria Almudena , Laguna-Gonzalez Ramon , Lopez-Echeverria Laura Yareli , Ojeda-Ramírez Deyanira , Oyervides Mayra
Published: May 2021

Human granulocytic Anaplasmosis (HGA), is a tick-borne infectious disease transmitted by ticks, resulting in acute feverish episodes. The etiological agent is the bacteria Anaplasma phagocytophilum; which is spread by ticks of the genus Ixodes spp. to complete its life cycle. In Mexico, there is only one case report. The primary challenge is understanding how other bacteria affect or overlap with the clinical manifestation of the disease. Sample collection occurred over the period September 2017 through October 2019. Blood samples from human subjects were obtained immediately after they signed consent forms. We analyzed for the presence for A. phagocytophilum by serological (IFA IgG two times) and PCR targeting 16SrRNA and groEL genes, followed by DNA sequencing. All patients with a history of travel abroad were dismissed for this project. In total, 1924 patients participated and of these, 1014 samples across the country were analyzed. Of these, 85 (8.38%) had IFA results that ranged from 1:384 to 1:896. Of the positive samples, 7.10% were used for PCR. Significant clinical manifestations included: dizziness, nausea, petechial, epistaxis, enlarged liver and/or spleen and thrombocytopenia. Hospitalization of at least 1.5 days was necessary for 3.2% of patients. None of the cases analyzed were lethal. This is the first clinical manifestations along with serological test results and molecular analysis confirmed the presence of A. phagocytophilum resulting in HGA in patients from Mexico. Health institutions and medical practitioners in general should include diagnostic testing for HGA among high risk populations and should recognize it as a vector-borne emerging infectious disease in Mexico.
A Compression-Based Method for Detecting Anomalies in Textual Data
Authors: de la Torre-Abaitua Gonzalo , Lago-Fernández Luis Fernando , Arroyo David
Published: May 2021

Nowadays, information and communications technology systems are fundamental assets of our social and economical model, and thus they should be properly protected against the malicious activity of cybercriminals. Defence mechanisms are generally articulated around tools that trace and store information in several ways, the simplest one being the generation of plain text files coined as security logs. Such log files are usually inspected, in a semi-automatic way, by security analysts to detect events that may affect system integrity, confidentiality and availability. On this basis, we propose a parameter-free method to detect security incidents from structured text regardless its nature. We use the Normalized Compression Distance to obtain a set of features that can be used by a Support Vector Machine to classify events from a heterogeneous cybersecurity environment. In particular, we explore and validate the application of our method in four different cybersecurity domains: HTTP anomaly identification, spam detection, Domain Generation Algorithms tracking and sentiment analysis. The results obtained show the validity and flexibility of our approach in different security scenarios with a low configuration burden.
3E-Net: Entropy-Based Elastic Ensemble of Deep Convolutional Neural Networks for Grading of Invasive Breast Carcinoma Histopathological Microscopic Images
Authors: Senousy Zakaria , Abdelsamea Mohammed M. , Mohamed Mona Mostafa , Gaber Mohamed Medhat
Published: May 2021

Automated grading systems using deep convolution neural networks (DCNNs) have proven their capability and potential to distinguish between different breast cancer grades using digitized histopathological images. In digital breast pathology, it is vital to measure how confident a DCNN is in grading using a machine-confidence metric, especially with the presence of major computer vision challenging problems such as the high visual variability of the images. Such a quantitative metric can be employed not only to improve the robustness of automated systems, but also to assist medical professionals in identifying complex cases. In this paper, we propose Entropy-based Elastic Ensemble of DCNN models (3E-Net) for grading invasive breast carcinoma microscopy images which provides an initial stage of explainability (using an uncertainty-aware mechanism adopting entropy). Our proposed model has been designed in a way to (1) exclude images that are less sensitive and highly uncertain to our ensemble model and (2) dynamically grade the non-excluded images using the certain models in the ensemble architecture. We evaluated two variations of 3E-Net on an invasive breast carcinoma dataset and we achieved grading accuracy of 96.15% and 99.50%.
Entanglement and Photon Anti-Bunching in Coupled Non-Degenerate Parametric Oscillators
Authors: Inui Yoshitaka , Yamamoto Yoshihisa
Published: May 2021

We analytically and numerically show that the Hillery-Zubairy’s entanglement criterion is satisfied both below and above the threshold of coupled non-degenerate optical parametric oscillators (NOPOs) with strong nonlinear gain saturation and dissipative linear coupling. We investigated two cases: for large pump mode dissipation, below-threshold entanglement is possible only when the parametric interaction has an enough detuning among the signal, idler, and pump photon modes. On the other hand, for a large dissipative coupling, below-threshold entanglement is possible even when there is no detuning in the parametric interaction. In both cases, a non-Gaussian state entanglement criterion is satisfied even at the threshold. Recent progress in nano-photonic devices might make it possible to experimentally demonstrate this phase transition in a coherent XY machine with quantum correlations.
Metal Organic Vapor Phase Epitaxy of Thick N-Polar InGaN Films
Authors: Hatui Nirupam , Krishna Athith , Pasayat Shubhra S. , Keller Stacia , Mishra Umesh K.
Published: May 2021

Hillock-free thick InGaN layers were grown on N-polar GaN on sapphire by metal organic vapor phase epitaxy using a digital growth scheme and H2 as surfactant. Introducing Mg to act as an additional surfactant and optimizing the H2 pulse time, In compositions up to 17% were obtained in 100 nm thick epilayers. Although Mg adversely affected the In incorporation, it enabled maintenance of a good surface morphology while decreasing the InGaN growth temperature, resulting in a net increase in In composition. The parameter space of growth temperature and Mg precursor flow to obtain hillock-free epilayers was mapped out.
A Fully Integrated AC-DC Converter in 1 V CMOS for Electrostatic Vibration Energy Transducer with an Open Circuit Voltage of 10 V
Authors: Ishida Yosuke , Tanzawa Toru
Published: May 2021

This paper proposes an AC-DC converter for electrostatic vibration energy harvesting. The converter is composed of a CMOS full bridge rectifier and a CMOS shunt regulator. Even with 1 V CMOS, the open circuit voltage of the energy transducer can be as high as 10 V and beyond. Bandgap reference (BGR) inputs a regulated voltage, which is controlled by the output voltage of the BGR. Built-in power-on reset is introduced, which can minimize the silicon area and power to function normally found upon start-up. The AC-DC converter was fabricated with a 65 nm low-Vt 1 V CMOS with 0.081 mm2. 1 V regulation was measured successfully at 20–70 °C with a power conversion efficiency of 43%.
A Simple WiFi Harvester with a Switching-Based Power Management Scheme to Collect Energy from Ordinary Routers
Authors: Angulo Fernando , Navarro Loraine , Quintero M. Christian G. Quintero , Pardo Mauricio
Published: May 2021

This paper shows the design process of a simplified harvesting circuit for WiFi at the 2.4 GHz frequency band based on the analysis of the environment available signals. Those signals and their power level define an antenna design to maximize captured energy and select the proper number of stages for a voltage multiplier so that an impedance matching network is no longer required. With this, it is possible to maintain the harvester architecture simple without sacrificing performance. The use of supercapacitors is preferred over batteries due to their high-power capacity, the ability to deliver high peak currents, long-life cycle size, and low cost. Hence, supercapacitor availability allows to devise a novel switching scheme that employs two units that favor energy use and speed up the recharging process. The built harvester exhibits a power conversion efficiency greater than 50% under an incident signal of 0 dBm in the rectenna. The tests are carried out in an academic environment using a multi SSID router, collecting 494 mJ without requiring special modifications in the router used as an energy source.
FFMCP: Feed-Forward Multi-Clustering Protocol Using Fuzzy Logic for Wireless Sensor Networks (WSNs)
Authors: Mishra Pankaj Kumar , Verma Shashi Kant
Published: May 2021

The restriction on the battery life of sensors is a bottleneck for wireless sensor networks (WSNs). This paper proposes a new feed-forward multi-clustering protocol (FFMCP) to boost the network lifetime. The utilization of fuzzy logic helps to overcome the uncertainties in the value of input parameters. The proposed protocol selects the most suitable cluster heads (CHs) using the multi-clustering method. A multi-clustering technique is defined utilizing the node’s information of the previous round and a fuzzy inference system to decide the CHs. The sensor nodes spend energy due to non-uniform CH distribution and long-distance data transmission by member nodes. The main focus of the proposed protocol is to reduce the member node distance. Our proposal distributes CH nodes uniformly using unequal clustering. The simulation outcome reveals that the proposed algorithm(FFMCP) has better performance in terms of tenth node death (TND), half node death (HND), remaining energy after 800 rounds (E_800), and average energy spent per round (AVG_PR) as compared to standard clustering schemes in the past.
Exploring Pattern of Green Spaces (GSs) and Their Impact on Climatic Change Mitigation and Adaptation Strategies: Evidence from a Saudi Arabian City
Authors: Maghrabi Ahmad , Alyamani Abdulelah , Addas Abdullah
Published: May 2021

Green spaces (GSs) are significant, nature-based solutions to climate change and have immense potential to reduce vulnerability to heat waves while enhancing the resilience of urban areas in the light of climate change. However, in the Saudi context, the availability of GSs across cities and their perceived role in climate change mitigations and adaptation strategies remain unexplored. This study aimed to examine the per capita availability of GSs in the Jeddah megacity in Saudi Arabia, and their role in climate change mitigation and adaptation strategies. This study assessed the per capita availability of GS in Jeddah city using GIS techniques, and a questionnaire survey (online and an onsite) was conducted to assess the GSs users’ perception of the role of GSs on climate change mitigation and adaptation strategies. Non-parametric tests were also used to find differences in roles based on socio-demographic attributes. The findings of the study revealed that: (i) the per capita availability of GS in Jeddah is relatively low in comparison to international organization recommendations (such as World Health Organization and European Union). As per the survey result, it was reported that GSs play crucial role for climate change mitigation such as temperature regulation, reduction in heat stress, enhancement outdoor thermal comfort, and the maintenance of air quality. More than 85% of the total respondents agreed with the very high importance of GSs for climate change mitigation. More than 80% of respondents in the city highly agreed with climate change adaptation strategies such as the enhancement of accessibility to GSs, ecosystem-based protection of GSs, and the improvement of per capita availability of GSs. The findings of the study will be very helpful to planners and policymakers in implementing nature-based solutions to reduce vulnerability to climate change in Jeddah city, and particularly other cities in a desert environment.
Influence of Climate Change on Tree Growth and Forest Ecosystems: More Than Just Temperature
Authors: Blanco Juan A. , González de Andrés Ester , Lo Yueh-Hsin
Published: May 2021

Recent research has shown that climate change is already altering tree species ranges, mortality and growth rates [...]
Spatial Distribution and Structural Characteristics for Haloxylon ammodendron Plantation on the Southwestern Edge of the Gurbantünggüt Desert
Authors: Song Chunwu , Li Congjuan , Halik Ümüt , Xu Xinwen , Lei Jiaqiang , Zhou Zhibin , Fan Jinglong
Published: May 2021

Haloxylon ammodendron (C.A.Mey.) Bge. is crucially important for stabilizing sand dunes in the desert area of the Junggar Basin and has thus been widely planted in the oasis–desert ecotone for windbreak and sand fixation purposes since the 1980s. The spatial distribution and structural characteristics of Haloxylon ammodendron plantations of three different ages—planted in 1983 (36a), 1997 (22a), and 2004 (15a)—on the southwestern edge of the Gurbantünggüt Desert were studied. The results showed that the spatial distribution patterns for the different stages of growth showed a trend of cluster that was random during the transformation from seedlings to juvenile and mature trees. Forest density for the 15a, 22a, and 36a plantations was, respectively, 1110, 1189, and 1933 plants ha−1; the base stem diameter for the main forest layer was 5.85, 8.77, and 6.17 cm, respectively, and the tree height was concentrated in the range of 1.5–3.0 m, 2.0–3.5 m, and 1.5–2.5 m. In the regeneration layers, the proportion of seedlings was the largest in all three stand ages, followed by juvenile trees, and mature trees only appeared in the 22a plantation. The proportion of deadwood in the 36a forest was the highest, and there were no mature trees in the regeneration layer. These results indicate that the three Haloxylon ammodendron plantation stages were in the period of rising at 15a, stable and degenerate with increasing age at 22a, and at 36a the regeneration ability was very weak and presented degradation due to species competition for soil moisture, because of too many seedlings and mature plants. In this case, measures such as thinning could be taken to prevent rapid degradation and to accelerate regeneration when the stand age exceeds 20 years. Considering the sand fixation effect, the pressure of competition for water resources, and forest capacity for renewal and sustainability, the most suitable forest density in the Haloxylon ammodendron plantation would be 8.5–9 m2 per plant.
Calibration of Electrical Resistance to Moisture Content for Beech Laminated Veneer Lumber “BauBuche S” and “BauBuche Q”
Authors: Grönquist Philippe , Weibel Gianna , Leyder Claude , Frangi Andrea
Published: May 2021

Electrical resistance measurements are often employed for the purpose of nondestructive long-term monitoring of wood moisture content (MC) in timber structures. As a structural material for high-performance load-bearing applications in such structures, beech laminated veneer lumber (LVL) enjoys a growing popularity. However, due to the processing of beech LVL affecting physical properties, calibration curves for bulk beech wood cannot be used. In this study, resistance was measured on 160 beech LVL samples equilibrated in four different relative humidity (RH) climates. The results show a difference not only between the beech LVL products “BauBuche S” and “BauBuche Q”, but also between measurements at two different depths. For each data set, parameters for calibration models using two and using three model parameters were determined by regression analysis to MC determined by the gravimetric method.