bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Sistem Akuntansi Penerimaan Kas Tunai dan Piutang Atas Jasa Service Pada Cv. Siger Elektro
Authors: Ashari Regina Salsabila , Oktaria, SE., MM Eka Travilta , SE., MM Dewi Silvia, , Alie Maria Septijantini , Febriani Erni
Published: September 2024

Sistem akuntansi merupakan organisasi dari formulir, catatan dan laporan yang dikoordinasi guna memberikan informasi keuangan yang dibutuhkan bagi pihak manajemen perusahaan untuk memudahkan pengelolaan perusahaan dan pengawasan untuk menjamin keamanan aktiva yang dimilikinya sehingga dengan adanya sistem akuntansi tersebut diharapkan berbagai kecurangan dan kesalahan dapat dicegah ataupun diminimalisir. Cv. Siger Elektro adalah perusahaan yang bergerak dibidang mekanikal elektrik khusus unit pendingin. Tujuan penelitian untuk mengetahui bagaimana prosedur penerimaan kas atas jasa service. Metode penilaian yang digunakan adalah metode kualitatif Analisis prosedur dimulai dari mencatat identitas konsumen, mencatat kelengkapan barang yang diservice, pengecekan, dan membuatkan invoice. Dokumen yang digunakan adalah dokumen invoice services. Catatan penerimaan jasa service yang digunakan adalah tanggal masuk dan nama. Hasil penelitian didasrkan pada unsur-insur penerimaan kas atas jasa service. Hasil penelitian menerangkan bahwa prosedur penerimaan kas atas jasa service secara keseluruhan cukup efektif., hal ini karena masih terdapat bagian unsur-unsur prosedur penerimaan kas atas jasa service yang belum diterapkan. Sebaiknya meningkatkan prosedur penerimaan kas atas jasa service yang telah ada sehingga dapat lebih efektif. Transaksi-transaksi perusahaan bertambah kompleks    menyebabkan dibutuhkannya informasi mengenai keadaan keuangan perusahaan. Disimpulkan bahwa peran dan fungsi penerimaan kas yang dilakukan di CV. Siger Electro baik tunai maupun piutang sudah sesuai begitu juga dengan standar operasi prosedur yang dibuat oleh CV. Siger Electro sudah sesuai dengan prosedur penerimaan kas tunai dan piutang secara teori.
PENGARUH TERAPI EYE MOVEMENT DESENSITIZATION AND REPROCESSING TERHADAP TINGKAT STRES PASIEN DIABETES MELITUS DI PUSKESMAS NAWANGSASI KABUPATEN MUSI RAWAS
Authors: Agustiana Agustiana , Marlena Feny , Nugraha Angga
Published: September 2024

Latar Belakang : Terdapat beberapa terapi psikologi yang digunakan untuk mengatrasi stres, satu diantaranya adalah terapi EMDR.Masalah penelitian adalah masih adanya pasien Diabetes Mellitus yang mengalami stres Puskesmas Nawangsasi Kabupaten Musi Rawas. Tujuan penelitian adalah diketahui pengaruh terapi Eye Movement Desensitization and Reprocessing terhadap tingkat stres pasien Diabetes Mellitus di Puskesmas Nawangsasi Kabupaten Musi Rawas. Metode Penelitian: Penelitian ini menggunakan desain penelitian pre experimental dengan penelitian yang digunakan adalah One-Group pre-post test design. Populasi sebanyak 729orang dan sampel dengan teknikpurposive samplingyaitu 10 orang. Jenis data penelitian adalah data primer dan sekunder. Analisis data pada penelitian ini menggunakan statistik uji t-test.Hasil Penelitian: Hasil penelitian ini adalah rata-rata tingkat stres pasien Diabetes Mellitus sebelum terapi Eye Movement Desensitization and Reprocessing di Puskesmas Nawangsasi Kabupaten Musi Rawas adalah 16,30.Rata-rata tingkat stres pasien Diabetes Mellitus setelah terapi Eye Movement Desensitization and Reprocessing di Puskesmas Nawangsasi Kabupaten Musi Rawas adalah 13,20.Ada pengaruh terapi Eye Movement Desensitization and Reprocessing terhadap tingkat stres pasien Diabetes Mellitus di Puskesmas Nawangsasi Kabupaten Musi Rawas hasil uji statistik didapatkan nilai p = 0,000, berarti 0,05 (α).Kesimpulan : Bagi Puskesmas Nawangsasi Kabupaten Musi Rawas agar bisa menggunakan SOP dapat menerapakan terapi Eye Movement Desensitization and Reprocessing sebagai metode alternative yang digunakan untuk mengurangi dan mengelola stres.Kata Kunci  :  Terapi Eye Movement Desensitization and Reprocessing, Tingkat Stres, Diabetes Mellitus.
HUBUNGAN KUALITAS PELAYANAN KESEHATAN DENGAN TINGKAT KEPUASAN PASIEN POST OPERASI
Authors: Udani Giri , Sunarsih Sunarsih , Sari Isma Yunita
Published: September 2024

Background: The hospital's duty as a health service institution is to provide quality health services and be responsible to the community, particularly in its coverage area. The quality of hospital services is significant in health service organizations. Increasing public awareness about health and health services encourages every health hospital to ensure that quality services are in its every service. Quality health services are health services that can meet patient expectations. To meet the expectations, the management must strive to guarantee the quality of their services. A good hospital provides quality care for patients according to standards. Implementation of the standards may improve their sense of safety, comfort, and satisfaction leading to recovery process. Purpose: This research determines the relationship between the quality of nursing services and the degree of post-operative patient satisfaction. Methodes: The research is an explanatory survey with a cross-sectional design. The study was conducted at Yukum Medical Center Hospital from March until April 2023. The sample was 100 post-operative inpatients selected using a purposive sampling technique. Data was collected using a questionnaire to measure the scale of patient satisfaction and the scale of the care service system. Result: didapatkan hasil p-value = 0,000 ɑ (0,05). Conclusion: there is a relationship between service quality and post-operative patient satisfaction.
Evaluation of the post-COVID multidisciplinary outpatient clinic at the Pulmonary Division of the Cantonal Hospital Winterthur from the patient’s perspective: a mixed-methods study
Authors: Wirz Markus , Nast Irina , Rausch Anne-Kathrin , Beyer Swantje , Hetzel Jürgen , Hofer Markus
Published: September 2024

AIMS OF THE STUDY: This prospective study, conducted with patients from the multidisciplinary post-COVID outpatient clinic at the Pulmonary Division of the Cantonal Hospital Winterthur, aimed to investigate changes in patients’ main symptoms, elements that aided in coping with the condition and satisfaction with the consulting and therapeutic interventions.
METHODS: After obtaining ethical approval, fifty patients were consecutively included in this longitudinal study, which incorporated three survey times post-consultation: t1 (0–7 days), t2 (4–8 weeks) and t3 (4–6 months). The survey comprised standardised questionnaires, including the Hospital Anxiety and Depression Scale, the Post-COVID-19 Functional Status scale and the Chalder Fatigue scale, along with study-specific questions regarding symptoms and reasons for consulting the post-COVID outpatient clinic. Additionally, ten patients were invited to participate in qualitative individual interviews at t2 and t3.
RESULTS: The study was conducted between November 2021 and February 2023. The median age of the 50 participants was 47 years (IQR: 36–55), with 66% (33/50) being female. Most participants (66% or 33/50) reported no pre-existing conditions prior to COVID-19 infection, and only six patients required hospitalisation during the acute phase of their infection. Visits to the multidisciplinary post-COVID clinic occurred approximately eight months post-infection, with referrals primarily made by primary care physicians (82% or 41/50). The majority of patients experienced persistent tiredness, exhaustion and fatigue (94% or 47/50), along with reduced physical performance (82% or 41/50), while pain or breathing difficulties were less frequently mentioned. At t1, around half of the patients were fully or partially unable to work, a proportion that reduced to around a third by t3. Symptoms generally decreased over time, with significant improvements observed between t2 and t3. However, subjectively perceived cognitive limitations worsened or were reported more frequently over time. Most patients (96% or 48/50) felt well cared for throughout their consultations. In qualitative interviews, patients highlighted the medical staff’s attentiveness and the time dedicated to consultations, which made them feel that their complaints were taken seriously and that they received appropriate information.
CONCLUSIONS: The results confirmed that the multidisciplinary post-COVID outpatient clinic met most respondents’ expectations. Patients found that the attentive interprofessional coaching was most helpful in coping with their illness. However, participants also noted long waiting times and expressed a desire for earlier admission to the clinic.
Evaluation of Image Quality and Radiation Safety at the Emergency Department for Disabled and Nondisabled Patients
Authors: Jambi Layal , Almitairi Abdulaziz , Sulieman Abdelmoneim
Published: September 2024

It is expected that diagnosable findings with high image quality are achieved for all patients in a safe environment. It is known that the emergency department presents a greater challenge for radiological technologist to perform safe radiology procedures and achieve high image quality. This study aims to evaluate the radiographic image quality and safety measures at emergency departments at the Saudi Ministry of Health hospitals in Riyadh based on the American College of Radiology guidelines. Image quality was to be evaluated using certain clinical criteria based on three parameters. Three radiologists evaluated the image, and radiological technologists completed a survey to assess the safety measures. A total of 55 procedures were investigated in the emergency department for disabled and nondisabled patients. The results showed that 31-43% of the images had high image quality and high diagnostic findings, while 5-25% of the images had poor image quality and low diagnostic values. Poor radiation safety and protection measures were reported by radiological technologists. The study recommends workshops to improve the awareness of radiation protection and promote patients’ safety culture in the emergency department.
Indoor Activity Monitoring Using Chaotic Dwarf Mongoose Optimization with Deep Learning for Elderly and Visually Impaired People
Authors: Alzahrani Jaber S. , Rizwanullah Mohammed , Osman Azza Elneil
Published: September 2024

Indoor activity monitoring systems guarantee the security and well-being of aging and visually challenged persons living in their homes. These systems employ several sensors and technologies for monitoring daily activities such as sleep patterns, movement, and medication adherence, offering appreciated perceptions of the user’s day-to-day life and overall health. The adaptability and accuracy of the deep learning (DL) approach generate human activity recognition (HAR), an essential tool for improving security, effectiveness, and personalized experiences in indoor spaces. HAR deploying DL approaches revolutionizes indoor monitoring by allowing specific detection and understanding of human movements. Deep neural networks analyze data from several sensors such as accelerometers or cameras to distinguish intricate action patterns. DL approaches automatically extract and learn discriminative features, making them appropriate for recognizing complex human actions in sensor data. However, choosing the suitable DL structure and optimizing its parameters is vital for a better solution. This article introduces Indoor Activity Monitoring using the Chaotic Dwarf Mongoose Optimization with DL (IAM-CDMODL) technique for elderly and visually impaired people. The IAM-CDMODL technique mainly intends to detect indoor activities to ensure the safety of the elderly and visually impaired people. At the initial stage, the IAM-CDMODL technique follows a bilateral filtering approach for image preprocessing. In addition, the IAM-CDMODL technique exploits the MobileNetV2 (MN-V2) model for learning complex and intrinsic patterns from the preprocessed images. Moreover, the CDMO model has been applied to the optimum choice of hyperparameters related to the MN-V2 approach. At the last stage, the deep convolutional neural network bidirectional long short-term memory method is applied to identify indoor activities. To ensure the improved detection performance of the IAM-CDMODL methodology, a wide range of simulations is executed on multiple cameras fall and UR Fall Detection datasets. The experimental validation of the IAM-CDMODL methodology portrayed a superior performance of 99.35% and 99.74% over recent models.
Systems Pharmacology, Molecular Modeling, and Molecular Dynamics Simulation Analyses Provide Insights into the Molecular Mechanism of Trianthema portulacastrum L. for the Treatment of Osteoarthritis
Authors: Alqahtani Safar M.
Published: September 2024

Osteoarthritis (OA), also referred to as degenerative joint disorder, is a common kind of arthritis that affects millions of people worldwide and is characterized by cartilage degradation in joints. Complementary alternative medicine has recently sparked interest due to the potential of bioactive phytochemicals to control molecular pathways with fewer side effects. This study utilized a network pharmacology (NP) approach to investigate the regulatory mechanisms of active constituents of Trianthema portulacastrum L. in treating OA. Active components were obtained from the indian medicinal plants, phytochemistry and therapeutics (IMPPAT) and KNApSAcK databases and the literature, while their related targets were obtained through the Swiss Target Prediction and STITCH databases. Additionally, OA-related targets were obtained from microarray datasets (GSE55235 and GSE55457) using the Gene Expression Omnibus. To annotate target proteins, the DAVID Gene Ontology database was utilized, while KEGG pathways were employed to analyze such signaling pathways in which potential targets are involved. The STRING database along with Cytoscape was utilized to establish protein–protein interaction networks, and CytoHubba’s degree centrality scoring was utilized to identify core genes. Molecular docking analysis was conducted using PyRx. The KEGG pathway and network analyses identified one gene named Jun proto-oncogene (JUN) as mainly involved in OA. Three active ingredients, namely quercetin, stigmasterol, and ecdysterone, were found to influence JUN expression and potentially act as therapeutic targets for OA. The three complexes (JUN_ecdysterone, JUN_quercetin, and JUN_stigmasterol) also revealed stable dynamics and showed no major conformational changes during the simulation time. These observations were validated in the simulation-based binding free energy analysis. The integrated NP and docking study suggested T. portulacastrum’s preventative effect on OA by targeting OA-relevant signaling pathways.
Strategies for Facilitating Social Integration of Children with Disabilities in Saudi Arabia
Authors: Medabesh Ali Mohammed , Malik Nadeem , Shafi Mohammed , Rashid Javaid
Published: September 2024

Children with disabilities face numerous challenges in society, requiring concerted efforts to facilitate their social inclusion. This study explores the experiences and perspectives of parents raising children with disabilities in Tabuk, northwestern Saudi Arabia, focusing on factors influencing social inclusion and strategies employed to promote it. Despite increasing awareness of disability rights and inclusion, children with disabilities continue to encounter barriers to social participation. Understanding the unique challenges faced by these children and their families is crucial for developing effective interventions and support systems. A total of 38 parents of children with disabilities participated in narrative interviews, providing insights into their experiences. The interviews, lasting approximately 40 min each, explored various aspects of raising a child with a disability and their integration into the community. Thematic analysis was used to identify common themes and patterns in the data. The study revealed several factors influencing the social inclusion of children with disabilities, including the sociopsychological microclimate within the family, support from relatives, engagement in community organizations, religious involvement, and the child’s attractiveness. Strategies such as organizing leisure activities, fostering sibling relationships, and active participation in community organizations were found to facilitate inclusion. Also, the study highlighted the importance of educational institutions, rehabilitation centers, and social services in promoting social integration. The findings underscore the significance of familial and community support in fostering the social inclusion of children with disabilities. Despite existing challenges, there is a growing recognition of the importance of inclusive practices and the need for collaborative efforts among families, communities, and service providers. Recommendations include enhancing support services, promoting inclusive education, and combating social stigma to create more inclusive environments for children with disabilities. By prioritizing social inclusion and adopting inclusive policies and practices, societies can ensure that all children, regardless of ability, have equal opportunities to participate fully in community life.
Employment Scenario for People with Disabilities (PWDs) in Saudi Arabia: Challenges and Opportunities
Authors: Medabesh Ali Mohammed , Malik Nadeem , Shafi Mohammed , Rashid Javaid
Published: September 2024

In the pursuit of creating an inclusive and equitable society, the Kingdom of Saudi Arabia has made significant headways to address the unique employment opportunities and challenges faced by individuals with disabilities. This paper uses descriptive research design and explores the complex landscape, examining governmental initiatives, vocational training programs, educational opportunities, and cultural attitudes that collectively shape the experiences of individuals with disabilities in the Saudi Arabian context. By focusing on the complexities of this dynamic interplay, the objective is to shed light on persistent challenges, existing strides, and the path forward toward fostering a more inclusive environment and livelihood for individuals with disabilities in Saudi Arabia.
Analisis Kepuasan Konsumen Pada Alfamart Di Kota Bima
Authors: Anshari M. Alfian , Ismunandar Ismunandar , Darmawan Imam
Published: September 2024

Abstrak: Penelitian ini bertujuan untuk menganalisis tingkat kepuasan konsumen terhadap layanan yang diberikan oleh Alfamart di Kota Bima. Metode penelitian yang digunakan adalah survei dengan menyebarkan kuesioner kepada konsumen yang berbelanja di Alfamart. Sampel penelitian ini adalah 100 responden yang dipilih secara acak. Hasil analisis menunjukkan bahwa mayoritas konsumen merasa puas dengan pelayanan yang diberikan oleh Alfamart di Kota Bima. Faktor-faktor yang paling berpengaruh terhadap kepuasan konsumen meliputi kecepatan pelayanan, keramahan karyawan, ketersediaan produk, dan kebersihan toko. Meskipun demikian, terdapat beberapa aspek yang perlu ditingkatkan, seperti ketersediaan produk yang lebih variatif dan peningkatan promosi produk. Penelitian ini memberikan kontribusi dalam memahami tingkat kepuasan konsumen terhadap layanan ritel di Kota Bima, serta memberikan rekomendasi bagi manajemen Alfamart untuk meningkatkan kualitas layanan dan mempertahankan loyalitas konsumen. Diharapkan hasil penelitian ini dapat menjadi masukan yang berharga dalam upaya meningkatkan kepuasan konsumen dan daya saing Alfamart di pasar ritel Kota Bima
CEO CHARACTERISTICS AND FINANCIAL REPORTING QUALITY IN LISTED CONSUMER GOODS COMPANIES IN NIGERIA
Authors: Okika Nkiru Philomena , Esther Oyeneye Temitope , Gbadebo Adedeji Daniel
Published: September 2024

This study investigates the connection between the CEO characteristics and the quality of financial reporting in Nigerian consumer goods companies. Data used was from the annual report of 10 consumer goods firms listed in the Nigeria Stock Exchange from 2013 to 2022. Using Ordinary least square regression, the research revealed that CEO gender and tenure have a positive and substantial effect on financial reporting quality. CEO financial expertise was found to be insignificant. The study concluded that long-tenure CEOs and female CEOs contribute to better financial reporting quality in the consumer goods industry. The study recommends among others that the board of directors of consumer goods firms in Nigeria should encourage gender diversity at the executive level through policies and initiatives that promote equal opportunities for women.
CSR INITIATIVES AND SUSTAINABILITY RESILIENCE IN NIGERIA'S OIL AND GAS INDUSTRY: A PLS-SEM APPROACH FROM LOCAL COMMUNITIES' PERSPECTIVE
Authors: Abdulsalam Tajudeen Alaburo , Tajudeen Rofiat Bolanle , Abubakar Abdulrahman , Babatunde Akeem Olamilekan
Published: September 2024

Despite its potential for economic growth and sustainable development, Nigeria faces social challenges including poverty, environmental degradation, and economic decline. In 2023, it ranked 146th out of 166 on the SDG index, with a poverty headcount of $2.15/day. Over the past two decades, Nigerian oil and gas companies have faced sustainability criticism, emphasizing the importance of CSR initiatives for triple bottom line sustainability. This study examines how the CSR initiatives of Nigerian energy companies impact the sustainability and resilience of the Niger Delta region. By using an explorative research design guided by positivism philosophy, 460 survey responses were collected from Niger Delta community members via Google Form and analyzed using PLS-SEM since the research framework of the CSR and COM-R model comprises five primary dimensions each. The study discovered that CSR initiatives have a significant impact on sustainability and resilience in the Niger Delta. This underscores that integrating socially responsible initiatives not only enhances the ethical standing of these businesses but also generates high strategic value, bolstering their sustainability and resilience. The research recommendations include reassessing CSR initiatives, increasing community engagement, and collaborating with regulatory bodies. This will foster community cohesion, adaptability, and voluntary compliance with industry standards and social norms within the community. The research's descriptive value lies in its empirical demonstration of the connection between CSR and sustainability resilience. Firms can use these findings to enhance their CSR efforts and improve sustainability and resilience in future business practices. The research acknowledges potential biases in data collection stemming from unequal online access among the members of Niger Delta communities, resulting in a partial representation of the diverse range of respondent behaviours across the continent, as various cultural, economic, and social factors can influence their survey responses.
Medienmanagement
Authors: Goetz Miriam , Wicher Jochen
Published: September 2024

This textbook covers all the areas of media management that are relevant for working in media professions. It explains the economic and business fundamentals of the media market, the history of the media, management activities, the challenges and forecasts of individual media sub-markets, marketing mechanisms, media law, entrepreneurship and new business areas in a clear and compact way. Practical cases and simple examples from everyday working life are used to explain the challenges and opportunities for media managers in an understandable way. Students and all others interested in this subject are thus given a well-founded, compact overview of all relevant topics in the field of media management.
Die Widerklage des Staates in ICSID-Schiedsverfahren
Authors: Müller Carla Elisabeth
Published: September 2024

States rarely file counterclaims in investment arbitration proceedings. Although the number of counterclaims has increased in recent years, this increase has been relatively modest. Against this backdrop, this thesis analyses whether there is an inherent obstacle to state counterclaims in ICSID arbitration proceedings. To this end, the author analyses the prerequisites of jurisdiction and close connection. She systematises the existing case law and literature according to her own criteria and develops standards for the assessment of jurisdiction and close connection. This thesis is thus both a scholarly analysis of the topic as well as a handbook on counterclaims in ICSID arbitration proceedings, filling a gap in the literature.
Das Recht auf Staatsangehörigkeit im Völkerrecht
Authors: Kämpfer Merle
Published: September 2024

Refugee movements have significantly expanded the phenomenon of statelessness. This has far-reaching effects on the legal status of individuals, ranging from entry and residence status to participation in political processes. At the same time, a right to nationality touches on the core of sovereign self-determination of states with regard to the definition of their own state association. Against this background, the work develops the extent to which a right to acquire a nationality under international law can be justified under treaty or even customary law and examines in detail the case law of international human rights bodies, in particular regional human rights courts.
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Authors: Mariñas Pequeño Santiago
Published: September 2024

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Feeding Problems, Nutrition Status and Gastrointestinal Problems of Children and Adolescents with Neurodisability in a Clinical Care Setting in Kenya
Authors: Obara Sarah , Kaindi Dasel Mulwa , Okoth Michael Wandayi , Marangu Diana
Published: September 2024

The prevalence of neurological impairment and disability in children ranges from 8 to 180 per 1,000 in low- and middle-income countries (LMICs). In Kenya, 2.2% of the population (0.9 million people) live with some form of disability. Neurodevelopmental delay, neurodisability, and malnutrition significantly contribute to the burden of disease globally and in Africa. This study aimed to assess mealtime problem behaviors, nutritional status, and gastrointestinal (GI) issues among children and adolescents with neurodevelopmental disorders (CAWND) in clinical care settings in Kenya. A cross-sectional study was conducted at Kenyatta National Hospital involving CAWND aged 3-17 from June 2021 to June 2023. The Daniel 1999 formula was used to determine the sample size. Data collection and coding were performed using the Open Data Kit. Data was analyzed using the R programming language (R Core Team, 2022). The Brief Autism Mealtime Behavior Inventory (BAMBI) tool assessed feeding problems. Descriptive statistics were used to summarize socio-demographic characteristics. Linear discriminant analysis was employed to assess differences in nutritional status indicators by neurodevelopmental diagnosis. Associations between feeding problems and GI issues in CAWND were tested, with significance set at p < 0.05. The study included 81 CAWND, comprising 40% with autism, 28% with epilepsy, 11% with cerebral palsy, and 21% with trauma. The median age was 12 years. Malnutrition was highest among children with cerebral palsy (56% stunting, 44% wasting, and 55% underweight). Regarding feeding problems, 100% of CAWND with cerebral palsy disliked sweet foods (p = 0.024). Conversely, 91% of CAWND with epilepsy were most willing to try new foods (p = 0.024), and 65% preferred crunchy foods (p = 0.011). Additionally, 75% of CAWND with autism disliked foods requiring extensive chewing (p = 0.000), and 100% of CAWND with trauma disliked foods prepared in a specificway (p = 0.039). The most common GI symptoms observed were constipation and diarrhea. CAWND experiences feeding problems and GI issues that adversely affect their nutritional status. Tailored strategies addressing the mealtime experiences, requirements, and preferences of CAWND are necessary. Interventions to improve nutritional status and manage GI problems are crucial for enhancing health and nutrition outcomes. Future research should explore the impact of feeding and GI problems on the health and nutrition of CAWND.
Virtual Screening of Antidiabetic Plant Phytochemicals for Analogues that Cause Beta Cell Regeneration
Authors: Kyalo Cynthia , Otieno Filex , Munene Samuel , Kagia Richard
Published: September 2024

Immune-mediated destruction of functional beta-cell mass is the key mechanism for the pathogenesis of type 1 diabetes mellitus. Currently, the mainstay conventional treatment for Type 1 Diabetes Mellitus is the use of exogenous insulin. These patients require lifelong insulin therapy, including daily parenteral insulin administration, by single or multiple doses. Some plant phytochemicals have been shown to cause beta cell regeneration, gradually restoring insulin production in diabetic animal models. This would shift treatment from palliative care to more of a curative approach. This study aimed to screen these phytochemicals' analogues with better potency, and pharmacokinetic and toxicological profiles. Genistein and quercetin plant phytochemicals were selected to be screened using an in-silico study design. ZINC database was used to obtain analogues, then the top 20 were selected for each, totaling 40 analogues, all of which were prepared using the software, Avogadro. Autodock vina embedded in Chimera was used for docking analysis at the epidermal growth factor receptor (erB1). Biovia Discovery studio was used to carry out ligand-enzyme interactions. SWISSADME was used for pharmacokinetic profiling and Protox for toxicological studies. Three hundred and forty-four and 365 analogues were obtained for genistein and quercetin, respectively, with similarity scores ranging from 99.6%-100%. Genistein (docking score= -6.0) had 12 analogues that were better in terms of docking scores while quercetin had 5(docking score= -6.5). Among these, ZINC000038418848 was the best analogue for genistein (-6.7) and ZINC000004731234 for quercetin (-6.8). Both genistein and quercetin did not violate Lipinski rules, had high GI absorption didn’t permeate BBB, were not P-glycoprotein substrates, and inhibited the enzymes CYP1A2, CYP2D6 and CYP3A4. LD50 for genistein and quercetin was 2500 mg/kg and 159 mg/kg respectively, indicating high toxicity for quercetin compared to genistein. Their analogues displayed similar pharmacokinetic and toxicological profiles, with few differences in docking scores, BBB permeation, synthetic accessibility, CYP enzyme inhibition, and LD50. In conclusion, 12 genistein analogues and 5 quercetin analogues had stronger binding affinity to erB1 than the parent compounds. The different ZINC compounds displayed varied pharmacokinetic and toxicological profiles, with a few having superior properties to their parent compounds.
Meninjau Kemandirian Anak Usia Dini melalui Gaya Pengasuhan Demokratis di PAUD As-Sa’adah Kota Cilegon
Authors: Haeriyah Haeriyah , Laili Mahsiani Mina , Mulyawan Galuh
Published: September 2024

This study aims to examine the influence of democratic parenting styles on the independence of early childhood in schools, highlighting the factors that support the development of such independence. The background of this research stems from the importance of independence in early childhood as a foundation for future academic and social success. Democratic parenting, characterized by open communication, children's participation in decision-making, and respect for their needs and feelings, is hypothesized to play a significant role in fostering children's independence. Using a qualitative method with in-depth interviews, the research findings indicate that children raised with democratic parenting are more capable of making their own decisions, showing initiative, and having higher responsibility in school. The discussion of this study emphasizes that in addition to parenting style, factors such as a supportive school environment, active teacher involvement, and collaboration between parents and the school also play an important role in shaping children's independence. The conclusion of this study affirms that the implementation of democratic parenting and a supportive school environment is crucial in developing early childhood independence. Recommendations are given to parents and teachers to strengthen communication and collaboration in supporting children's independence in school, to ensure their readiness in facing future educational challenges.
Condiciones laborales y perfil de salud de trabajadores informales de la feria libre del mercado de una comunidad de Chile
Authors: Chandía Reyes Verónica , León Pino José , Luengo Martínez Carolina , De la población trabajadora informal GEPTI Grupo para el estudio
Published: September 2024

Objetivo: Determinar las condiciones laborales y el perfil de salud de los trabajadores informales de una feria libre de una comunidad de Chile. Método: Estudio observacional descriptivo de corte transversal. La muestra correspondió a 69 trabajadores de la feria libre del mercado de Chillán. La recolección de datos se realizó mediante un cuestionario de antecedentes sociodemográficos, laborales y el SF-36. Resultados: El 80,8% de los que trabajaban más de 12 horas diarias eran hombres. En salud, el 42% tenía enfermedades crónicas, el 43% usaba medicamentos crónicos, y el 55% no asistía a controles de salud. En salud mental, más del 40% reportó mala vitalidad y el 25% tenía mala función social. Conclusión: Se destaca la necesidad de formalizar el empleo y abogar por programas de apoyo integral para preservar la salud de estos trabajadores que consideren perspectivas de género.
Students’ Perception on The Use of Movie Clips at Cake Application toIncrease Vocabulary
Authors: Wanda Anastania  , Syafrizal Syafrizal , J Pahamzah
Published: September 2024

This research was intended to determine students’ perceptions on the use of Cake application in learning vocabulary. Specifically, there are two objectives of the research: 1). To find students' perceptions on the use of movie clips at Cake application to increase student vocabulary, 2). The advantages and disadvantages in learning English using movie clips at Cake application. This research used qualitative descriptive method. The participant of the research is students of the tenth-grade at SMA Islam Al-Azhar 6 Cilegon. To collect the data, this study used an open-ended questionnaire. The finding concluded two items. First, students’ perceptions on the use of movie clips at Cake application to increase student vocabulary. The results showed that students had positive perception regarding the use of movie clips at Cake application to increase student’s vocabulary. From students’ point of view, students agree that the use of movie clips feature at Cake application is really helps them in learning vocabulary, because learning to use this feature will be more fun, easier to understand and suitable for beginners. Second, the advantages of the movie clips at Cake application are the material that is very easy to learn and easy to remember because the movie clip is repeated many times so that students can memorize it more easily. The disadvantage is some respondents think that this feature duration of the movie clips provided is too short, and others said that there are no disadvantages to this feature.
Peran Teknologi dalam Meningkatkan Motivasi Belajar Siswa
Authors: Khairo Nadia Tul , Hairani Esi
Published: September 2024

The purpose of this study was to find out information or analyze the role of digital technology in increasing student motivation. Digital technology is an important tool in the learning process in the era of the industrial revolution 4.0 so that in all domains it is expected to be able to apply it, including the field of education, which in fact is students who study three years in school who are the successors of the next generation who are required to be able to compete in technological developments. This study uses a qualitative method with a case study approach using purposive techniques and snowball sampling to obtain data from resource persons at the State Vocational High School 1 Simpang Kiri Subulussalam City majoring in Multimedia. Furthermore, the findings or results in research that the role of digital technology in the multimedia department is able to provide learning motivation for students to be able to create innovative and creative works so that with the application of digital technology in learners can produce productive students. However, facilities such as computers in schools are not adequate or not enough to meet computer-based education standards, which are still minimal. So, it is hoped that for the next generation the computer facilities have been fulfilled in order to create effective learning.
A Guide to Ambient Air Particulate Control for Environmental Engineers
Authors:   Universiti Malaysia Perlis, Yusuf Sara Yasina , Jamian Nor Ruwaida , Naidu M. Dewika , Mohd Paad Khairunnisa , Ramli Norazrin
Published: September 2024

Amidst Malaysia's thriving industrial sector, addressing air pollution is a pressing and imperative task that requires understanding and decisive measures. A Guide to Ambient Air Particulate Control in Environmental Engineering serves as a valuable resource, providing crucial information and powerful techniques for anyone dealing with the intricate aspects of industrial processes. This book primarily explores Malaysia's regulatory structure, providing an analysis of the complex network of regulations that govern pollution discharge. It places significant emphasis on the importance of adhering to environmental statutes. By conducting thorough and careful examination, readers are prepared to effectively navigate this complex legal terrain with assurance, comprehending their crucial role in maintaining Malaysia's air quality requirements. The core of this highly helpful resource is a vast array of techniques for controlling air pollution, presented in the form of A Guide to Ambient Air Particulate Control in Environmental Engineering. In this context, collaboration is highly valued, emphasizing the need for cooperation and the sharing of expertise across the whole sector. Engineers, managers, and leaders are encouraged to form alliances, utilizing the combined knowledge and expertise to bring about a new era of environmental sustainability. However, this work goes beyond mere theory and instead provides a practical manual for organizations that are dedicated to making a significant environmental difference. By using easily understandable language and clear review, it stimulates a fundamental change in thinking, presenting sustainability as a crucial and necessary strategy for long-term success.
ENTREPRENEURSHIP AND THE THEORY OF PLANNED BEHAVIOUR A Comparative Study of Malaysia, Pakistan and Thailand
Authors:   Universiti Malaysia Perlis, Saraih Ummi Naiemah , Soomro Bahadur Ali , Shah Naimatullah , Johari Atikah Nor
Published: September 2024

Entrepreneurship is an energetic process for the creation of a new business or venture. Today, it plays a central role in both developed and developing economies, which grapple with significant challenges, including globalisation, population explosion, social development deficits, economic competition and economic downturns. This book uncovers the realm of individuals' intentions toward entrepreneurship with the support of the Theory of Planned Behaviour (TPB), for which we have developed a comprehensive theoretical framework. In the opening chapters, we spotlight the significance of entrepreneurship in three selected developing countries: Malaysia, Pakistan and Thailand. We offer an in-depth examination of entrepreneurship education in these countries, highlighting the strategies and initiatives aimed at nurturing the entrepreneurial spirit. As previously mentioned, TPB serves as the foundational theory, focusing on three core elements: attitude toward becoming an entrepreneur, subjective norms and perceived behavioural control. Subsequently, we present several empirical findings on entrepreneurial intentions among students in these nations, utilising the TPB as our guiding framework. Finally, drawing on the insights gained from the application of TPB, we conclude this book by elucidating which factors are most predictive of entrepreneurial intentions in Malaysia, Pakistan and Thailand. This book contributes to the existing literature on entrepreneurship as well as the TPB theory, offering valuable insights to scholars and researchers from related fields seeking a deeper understanding of entrepreneurship. Moreover, this book is a valuable resource for policymakers and government agents aiming to alleviate the burden of unemployment within their respective countries. It is our hope that this work will serve as a catalyst for positive change and innovation, inspiring individuals to embark on their entrepreneurial journeys and collectively shaping a brighter future for their nations.
Temas de Guardia en Neurología
Authors: Arroyo Quiñonez Isis María , Calle Cantos Wendy Maritza , Calle León Freddy Daniel , Lara Bedón Hamilton Andrés , Torres Criollo Larry Miguel , Lojano Munzón Esteban German , Matute Alao David Sebastián , Moncayo Rodríguez Adriana Patricia , Ortega Vázquez Nataly Estefanía , Palma Intriago Fabricio Javier , Pauta Verdugo Paula Victoria , Pérez Guijarro Yaritza Jamileth , Perugachi Marcillo Kevin Robinson , Quezada Matute Eva Alexandra , Quiñonez Boconsaca Jennifer Mariuxi , Salinas Huerta María Caridad , Jaramillo Parede Gabriela Mishell , Samaniego Jara Gerald Alexander , Vega Valladarez Lisbeth Esthela , Valladolid Sangurima Jennifer Liliana
Published: September 2024

Prólogo La Neurología es una disciplina médica que abarca el estudio y tratamiento de los trastornos del sistema nervioso. Este libro busca proporcionar una guía completa y actualizada sobre diversos temas de neurología que son de vital importancia tanto en la práctica clínica como en situaciones de guardia. Cada capítulo ha sido meticulosamente preparado por estudiantes comprometidos con la excelencia académica y el avance del conocimiento médico, bajo la supervisión de sus docentes tutores. Este esfuerzo conjunto asegura que el contenido sea no solo científicamente riguroso, sino también relevante y accesible para profesionales y estudiantes de la salud. El libro se organiza en los siguientes 11 capítulos de patologías neurológicas frecuentes en la atención diaria de la práctica médica. El trabajo con la editorial REDLIC (Red Editorial Latinoamericana de Investigación Contemporánea) ha permitido que este libro sea de acceso gratuito (Open Access), lo que facilita su difusión y el acceso a información científica actualizada. Las fuentes utilizadas para la elaboración de los capítulos incluyen Uptodate, libros de neurología y artículos científicos recientes, asegurando la calidad y relevancia del contenido. Además, este libro ha pasado por varios filtros en el proceso editorial, incluyendo un riguroso proceso de revisión por pares. Esto garantiza que el contenido no solo cumple con altos estándares académicos, sino que también ha sido evaluado y validado por expertos en la materia, asegurando su precisión y pertinencia. Dirigido especialmente a profesionales de la salud y estudiantes de medicina, esperamos que este libro sea una herramienta valiosa, proporcionando información clave que pueda ser utilizada en la práctica clínica diaria y en situaciones de guardia, contribuyendo así al mejor manejo de los pacientes neurológicos. Dra. Gina Heredia
Kai Herrmann
Authors: Herrmann Kai
Published: September 2024

In preparing for this project, I grappled most on how best to approach it. My intention was to shift focus away from me and instead shed light on the bond formed with my fellow soldiers, who became akin to family during our deployment to Iraq in 2003. Before heading out, I was on the brink of completing my bachelor's degree in education with a minor in history, a subject I hold dear due to its profound impact on shaping our world. From witnessing historic milestones like the fall of the Berlin Wall to the fall of Baghdad, each moment has left a profound mark on me and has deepened my world perspective. I was keenly aware that this deployment would not merely be an observation of history, but a direct participation in it. In the absence of cell phones, I brought with me many disposable cameras to capture our journey. Selecting images for this project was a challenging task; each frame had to narrate a chapter of our story faithfully. When it came time to record my presentation, authenticity was my most important goal. I did not want to present a rehearsed script, as I feared it would negatively affect the natural flow of my emotions and memories for each picture. This was a singular opportunity, and I dove in headfirst, navigating the challenge was very difficult for me. Though the final product may not be flawless, it is from my heart, and it is my best effort to honor those who sacrificed everything. Yet there remains a painful reminder of lives lost encapsulated in several undeveloped roles of film. For nearly two decades I have struggled with the decision to develop them. Knowing they contained the final images of some loved one’s son, daughter, husband, or wife, who never returned. The thought of their smiling faces, unaware that this would be their last day on earth, is a burden I cannot bear. Perhaps one day, I will find the strength to confront those images honoring the memory of those who gave it their all.
Gerald Natalroman (Nate)
Authors: Natalroman Gerald
Published: September 2024

My vision for this project and how I imagine it to be interactive is with the help of Technology lead Dr. Khoi Nguyen, I Decided to have items three dimensional scanned that chronicle my military career and the duty Assignments. At the Age of 17, I found out that my girlfriend at the time who would eventually become my wife was pregnant with our first child. I decided to enlist into the Texas National Guard in the summer of 96 under the split option program, the first scanned item scanned which is a picture of me, my dad Juan NatalRoman who also served in the army with 23 years of service and my girlfriend/Wife Kristen and newly born daughter Viktoria covers that time in the 49th Armored Discom, Tx. National Guard. The first Item scanned first the wooden Wilkommen Sign covers my time in Germany where I deployed on a Peacekeeping mission to Kosovo, attend Special Forces Assessment and Selection. The second Item scanned covers my time at Ft. Hood, Tx which is the III Corps Phantom Warriors Coin where I deployed to Iraq for the first time and Kuwait. The Next Items that scanned are the Concrete Wall barrier and the replica Hawaiian War club covers my time stationed with the 25th Infantry Division, Schofield Barracks, Hawaii and my next two deployments to Iraq. The next item scanned is the wooden circle plaque which covers my special duty assignment as Platoon Sergeant at the Advanced Individual Training Site at Ft. Sam Houston, San Antonio Texas. The next item scanned is the mounted Bayonet that I received for my time at the General Leonard Wood Army Community Hospital at Fort Leaonard Wood Missouri and the last item scanned Is the wooden plaque with the phrase “It is what It Is” which was my mantra for most of my Military Career and covers my last duty Station at the Brooke Army Medical Center, Ft. Sam Houston, Tx. During My Time in the service, I’ve learned what it truly meant to sacrifice, being part of something that was bigger than myself. I learned what it meant to be a servant leader, putting others needs above my own and sometimes those of my family as well as the resilience of the Human Spirit, but of all the things that I most proud of is that I was able stay married to and share all of these times good, bad and or indifferent, the person who held the family together during all of the missed birthdays, holidays and Anniversaries, The love of My life Kristen E. NatalRoman.