bluuebunny/crossref_metadata_2025 huggingface dataset:
Digitalisierung der Engineering Prozesse durch System Lifecycle Management (SysLM)
Authors: Eigner Martin
Published: September 2021

Dieser Beitrag erläutert die Umsetzung der Digitalisierung speziell im Anwendungsgebiet des Engineering. Dabei wird die Digitalisierung, sowohl des eigentlichen Produktes als auch der im Rahmen von Service-orientierten Geschäftsmodellen entwickelten Dienstleistung, vorgestellt. Ein weiterer wesentlicher Punkt der Digitalisierung sind die horizontale und vertikale Integration der technischen und administrativen Arbeitsprozesse entlang des Produktlebenszyklus. Bei den vertikalen Integrationen handelt es ich um die Integrationen der Autorensysteme entlang den Lebenszyklusphasen Anforderungsmanagement, Systemarchitektur, CAD in Mechanik, Elektronik, Softwareentwicklung, Simulation, Test, Prozessplanung und Digitale Fabrik. Bei der horizontalen Integration stehen die administrativen Funktionen wie Freigabe-, Änderungs- und Konfigurationsmanagement über den gesamten Produklebenszyklus und die technische Integration der in den einzelnen Produktlebenszyklus-Phasen erzeugten Informationen im Vordergrund. Hier ist vor allem die Verteilung und Orchestrierung der Funktionen zwischen SysLM, MES und PPS relevant.
Una aproximación a la situación de las mujeres en el Irán contemporáneo: perspectivas locales y globales
Authors: Gutiérrez Luna Alejandra , Fuentes Arzate Iraís
Published: September 2021

El objetivo de este artículo es destacar algunos de los factores que influyen en la situación actual de las mujeres en Irán. Se sostiene que su posición en la sociedad puede ser entendida a partir de la influencia de factores locales y globales. Los locales son la ley de la familia, las características del sistema político iraní y las condiciones educativas y laborales. Respecto a los factores globales, se hace énfasis en las agendas de los organismos internacionales, las sanciones económicas impuestas por el gobierno estadounidense y los movimientos feministas transnacionales.
De la revolución de Rojava a la construcción de la Federación Democrática del Norte y Este de Siria.
Authors: Hernández Rodrigo Rubén
Published: September 2021

El 19 de julio del 2012 comenzó en Rojava, región kurda en el norte de Siria, un proceso revolucionario mediante el cual se puso en práctica un proyecto político llamado Confederalismo Democrático. Los pueblos de la región, frente a la guerra entre el régimen de Bashar al-Asad y el Ejército Libre Sirio, optaron por la construcción de una tercera vía para la solución del conflicto: el ejercicio político de base por parte de la población civil. A partir de su organización en comunas han comenzado a satisfacer el conjunto de sus necesidades sociales y a generar una forma de convivencia con base en el respeto a la diversidad. En el presente ensayo propongo una periodización de esta práctica autonómica a partir de las transformaciones en su organización político-administrativa, que ha permitido su crecimiento territorial y su fortalecimiento en términos políticos, y que ha llevado a la conformación de la Federación Democrática del Norte y Este de Siria.
La mujer en Libia. Un antes y después de la Revolución de 2011 (2005-2015)
Authors: Jiménez Moreno Jorge Ángel
Published: September 2021

La participación de la mujer libia en la Revolución de 2011 fue sin duda manifestación de si mismas como agentes de cambio. Sin embargo, una vez terminada la Revolución libia, su situación entró en crisis hasta encontrarse en las condiciones precarias actuales. A diferencia del régimen gadafista, en donde la mujer libia alcanzó proezas muy sustanciales, su condición en el período post gadafi ha observado un retroceso de enorme envergadura, materializado en la nula agencia y poca -e incluso inexistente- voz política en los asuntos nacionales. Además, la inestabilidad provocada por las tensiones entre las facciones existentes en Libia y aunado a ello, con el restallido del conflicto en 2014, la posición de la mujer se ha deteriorado crecidamente. El presente artículo tiene como objetivo comparar la situación de la mujer libia entre ambos períodos, de modo que se busca subrayar las implicaciones que el conflicto ha tenido para con la mujer y su situación en el nuevo Estado de Libia.
Relaciones especulares entre Marruecos y América Latina: de la generación Beat a la diplomacia cultural
Authors: ROJO FLORES SANDRA
Published: September 2021

En el presente artículo se considera que Marruecos y América Latina han fortalecido sus lazos y comunicación gracias a las plataformas virtuales, lo que contribuye a establecer una relación Sur-Sur que se venía gestando desde hace tiempo. Se dan algunos ejemplos de las relaciones entre estas dos geografías, haciendo alusión a algunos momentos y situaciones como los “años de plomo” marroquíes; la imagen de Marruecos como objeto de estudio heredado de la literatura antropológica; el paralelismo de Marruecos y México en la mirada de la generación beat y los recientes proyectos e iniciativas que desplazan el sujeto-objeto hacia el sujeto-sujeto.
Discursos hegemónicos y decolonialidad sobre el dîn en el islam
Authors: García Linares Ruth Jatziri
Published: September 2021

Reseña del libro: Genealogía del monoteísmo. La religión como dispositivo colonial, de Abdennur Prado, México: Akal 2018.
Enactivism and Correctional Science: An Analysis of Forensic Treatment of Agency in a Neoliberal Climate
Authors:   , O'Neill Samuel
Published: September 2021

In correctional practice, as primarily informed and driven by the Risk-Need-Responsivity (RNR) practice framework of Bonta and Andrews (2017), theoretical explanations of agency bear significance in their representation and consequent treatment of ‘criminal’ agents. Due to a state of ‘theoretical illiteracy’ however, this domain remains largely divorced from the insights offered by current affective science (Ward, 2019). The purpose of this paper is to outline key principles offered within an ‘enactive’ paradigm; a contemporary strand of cognitive science that depicts cognition as embodied, embedded and enactive, ultimately submitting a relational cognitive-affective agency, constituted of habits of bodies and minds (Maise & Hanna, 2019; Ward, Silverman & Villalobos, 2017). Enactivism offers various elements that contrast with traditional internal ‘cognitivist models’ of agency, which inform mainstream correctional practice; these include the active, affective and social nature of cognition, which as is illustrated, lends emphasis to the impact of prevalent ideologies, through institutions, upon agents (Maise & Hanna, 2019). In this project I outline current correctional treatment of agency, as it stands in contrast to insights offered by enactive accounts, and as embedded in a broader neoliberal context. Therefore I provide some critical examination of the relationship between psychological theory and neoliberal ideology, specifically focusing on principles of individualism and self-governance it is purported to cultivate. In conclusion I maintain that the RNR provides a thin representation of agency that is driven by an internal and limited perspective of functioning that precludes aspects essential to the personhood of agents including its active, affective and phenomenological nature. As embedded in a neoliberal context, I argue that this significantly limits rehabilitative practice, and reifies an abstraction of mindedness from material and social contexts. A pluralistic approach to rehabilitation is therefore necessary, including the enactive and related perspectives expounded in this piece, in order to provide explanation and therefore practice beyond entrenched normative assumptions of agency and human function.
Use of FISH technique in the diagnosis of chromosomal syndromes
Authors: Iqbal M. A. , Ulmer C. , Sakati N.
Published: September 2021

Major chromosome abnormalities are present in 0.65% of all neonates. Fluorescent in situ hybridization [FISH]is useful in diagnosing microdeletion syndromes that would otherwise be difficult to diagnose using standard cytogenetics. In this study, we used FISH analysis in the laboratory diagnosis of 4 patients with Prader-Willi Syndrome [del[15][q11.2q12], 4 patients with Di George syndrome [del[22][q11.2q11.23] and 4 patients with Williams syndrome [del[7][q11.23q11.23]. High-resolution chromosome analysis in all these patients was either normal or inconclusive but all the syndromes were confirmed using FISH. We recommend cytogenetic analysis should always be supplemented with FISH to diagnose all cases suspected of a microdeletion syndrome
Geographic distribution of cystic fibrosis transmembrane regulator gene mutations in Saudi Arabia
Authors: Banjar H.
Published: September 2021

A descriptive study was undertaken to characterize cystic fibrosis transmembrane regulator [CFTR] gene mutations in the Saudi Arabian cystic fibrosis [CF] population in relation to their clinical picture, demographic features and ethnic origin. From October 1992 to September 1997, 70 patients [46 families]diagnosed with CF were screened for CFTR mutations. A total of 12 mutations were identified in 34 families [70% of the CF alleles in the study group]. Most of the families were native Saudis, and in 88% of the families the parents were in consanguineous marriages. The most common Saudi mutations were 1548delG and I1234V. There was no significant difference in the clinical picture between patients of different ethnic origins with the same CFTR mutation
Diabetes mellitus, hypertension and obesity-common multifactorial disorders in Saudis
Authors: Warsy A. S. , El Hazmi M. A.
Published: September 2021

Diabetes mellitus, hypertension and obesity are among the multifactorial disorders that occur at a higher prevalence in older age groups. Their prevalence is affected by both genetic and environmental factors. We investigated the distribution of diabetes mellitus, hypertension and obesity in Saudi males and females by conducting a household screening survey during the period 1992-1996 of the adult population [>14 years] in five different areas of Saudi Arabia. Height, weight, age and other essential details were recorded and diastolic and systolic blood pressures measured. Glucose levels were measured in blood taken after fasting and 2 hours after a glucose load. The data were used to classify the individuals as diabetic, glucose intolerant and normal, using WHO criteria. The individuals were further classified as type 1 diabetes mellitus and type 2 diabetes mellitus. The overall prevalence of diabetes mellitus was 9.7% and 7.0%, obesity 13.05% and 20.26%, overweight 27.23% and 25.20%, and hypertension 5.39% and 3.65% in the adult male and female populations respectively. A significant increase was observed in the prevalence of diabetes, obesity and hypertension with age in both males and females. In addition, the prevalence of obesity and overweight was significantly higher in the individuals with diabetes mellitus
DECENTRALIZED ELECTRONIC VOTING USING SMART CONTRACTS (DEV-SC)
Authors: Waheed Urooj
Published: September 2021

For a citizen, voting is the fundamental tool to bring change in the country for good governance, through electing suitable candidates or a party to give them the power to govern. There are many forms of elections be it in the democratic or monarch systems. Each way, the vote has the power to elect the next people’s representatives. For a long time, paper-based voting was the only system being used globally for years; after the dot-com bubble, many countries emerged with electronic voting. But the problems such as security, transparency, and integrity of elections and the voting process are still under question. The issue with paper-based voting was accessibility, voter turns around and tallies, electronic voting has its own advantages and disadvantages such as a single point of failure, trustful systems, and loopholes to forge the electronic voting systems to alter the outcomes. To solve the problems related to the electronic voting process security, integrity, and transparency, an advanced approach is required to adopt. With the advancement of technologies, 4th industry revolution technologies give us Blockchain, Distributed Ledger and Smart Contract types of technologies which may be beneficial to solve the current problems in electronic voting systems. In this paper, we proposed a research-based case study to implement Decentralized Electronic Voting using Smart Contracts (DEV-SC) to solve security, transparency, and integrity-related problems available in the electronic voting process. This will ensure and enhance the voting process easily, trustable, and verifiable.
Implications of Social Media Addiction on Academic Performance among Generation Z Student-athletes during COVID-19 Lockdown
Authors: Wan Pa Wan Ahmad Munsif , Mahmud Muhammad Sofwan , Zainal Mohd Syazwan
Published: September 2021

With the rapid advancement of internet technology, the increasing prevalence of smartphone ownership at a young age, the uncertainty surrounding the end of the COVID-19 pandemic, and the effect of social media addiction on academic performance among students, social media use will continue to be a major point of contention. However, student-athletes are a distinct group of students who should not be overlooked due to their concurrent commitments to studying, training, and competing. As such, this study sought to investigate the effect of social media addiction on academic performance among Generation Z student-athletes during Malaysia's COVID-19 lockdown. The research design used in this study was a quantitative cross-sectional survey. This study surveyed 91 respondents and utilized the Social Media Addiction Questionnaire (SMAQ) and Grade Point Average (GPA). The findings indicated that Facebook was the preferred social media platform over Instagram, Twitter, and YouTube, and that more than half of the participants were social media addicts. The researchers concluded that social media addiction had a significant impact on academic performance, accounting for 57.6 percent of the variance. These findings imply that excessive social media use, leading to addiction, has a significant negative effect on academic performance. Solutions are desperately needed, such as turning off notifications, silencing the phone, engaging in home workouts, reconnecting with family, or taking up new hobbies.
PERAN MANAJERIAL KEPALA SEKOLAH DALAM PENINGKATAN MUTU SDN MUKIRAN 04 KECAMATAN KALIWUNGU KABUPATEN SEMARANG
Authors: Dewi Lestari Dewi Lestari , Murniati Ngurah Ayu Nyoman
Published: September 2021

Fokus dari penelitian ini adalah peran manajerial kepala sekolah dalam peningkatan mutu SDN Mukiran 04 Kecamatan Kaliwungu, Kabupaten Semarang. Dari hasil penelitian di lapangan dan analisis, dapat ditarik simpulan sebagai berikut:Kepala Sekolah, sebagai pimpinan dan manajer berhasil menyerasikan kultural dan sistemik secara berimbang saling mengisi dan saling menguatkan dalam penyelenggaraan sekolah. Keberhasilan tersebut selaras dengan peran manajerial Kepala Sekolah yang mencakup peran kepemimpinan yang terdiri dari lima tugas utama, yakni (1) Planning (perencanaan), (2) organizing (pengorganisasian), (3) commanding (perintah), (4) coordinating (pengkoordinasian), dan (5) controlling (pengawasan) menentukan mutu proses dan hasi kegiatan belajar dan mengajar di sekolah. Serta fungsi Kepala Sekolah sebagai manajer penyelenggaraan lembaga pendidikan yang mengelola rangkaian kegiatan yang terpadu dalam kegiatan-kegiatan penyelenggaraan sekolah per hari demi hari secara konsisten dan berkelanjutan yang mencakup enam (6) peran-fungsi manajerial, yakni (1) fungsi perencanaan, (2) fungsi pengorganisasian, (3) fungsi pengarahan, (4) fungsi pengkoordinasian, (5) Fungsi komunikasi, dan (6) fungsi pengawasan.Studi kasus (best practice) dari SDN Mukiran 04 Kaliwungu ini dapat menjadi cermin dan sumber belajar berharga bagi pihak sekolah umumnya, dan para kepala sekolah bahwa satu sekolah (pendidikan) sekalipun berada di perdesaan dalam situasi dukungan finansial dan sarana-prasarana yang minimum, tetap dapat diselenggarakan dengan baik dan bahkan tetap bisa berprestasi, sepanjang ada kemauan dan komitmen untuk berubah lebih baik.
Komparasi Algoritma Random Forest dan Decision Tree untuk Memprediksi Keberhasilan Immunotheraphy
Authors: Pamuji Fandi Yulian , Ramadhan Viry Puspaning
Published: September 2021

Menjaga kesehatan merupakan tugas pada diri kita sendiri sebagai manusia, dengan tubuh yang sehat kita dapat melakukan aktifitas dan produktifitas kita sehari-hari. Kesehatan adalah keadaan seimbang yang dinamis, dipengaruhi faktor genetik, lingkungan dan pola hidup sehari-hari seperti makan, minum, kerja, dan istirahat. Immunotherapy merupakan metode pengobatan untuk mengobati penyakit kanker kulit yang dimana metode ini meningkatkan sistem kekebalan tubuh untuk mengatasi penyakit kutil. Immunotherapy merupakan pengobatan efektif untuk penyakit kutil. Metode ini memiliki respon yang lebih baik membutuhkan lebih sedikit sesi, dan mampu mengobati kutil yang sudah lama. Berdasarkan hasil pengujian metode Random Forest dan Decision Tree terhadap prediksi keberhasilan pengobatan imunoterapi untuk penyakit kutil menggunakan bahasa Python, maka dapat diambil kesimpulan bahwa hasil pengujian metode Decision Tree masih terdapat prediksi yang tidak tepat dengan tingkat akurasi 84,4 % kemudian metode Random Forest prediksinya tepat dengan tingkat akurasi 85,5 %. Hasil pengujian tersebut menunjukkan bahwa metode Random Forest merupakan metode yang lebih unggul dibandingkan dengan metode Decision Tree.
Analisis Kebiasaan Berolahraga di Masa Covid-19 Menggunakan Kerangka Kerja Gamifikasi Octalysis
Authors: Maukar Anastasia L , Marisa Fitri , Vitianingsih Anik Vega , Puspitarini Erri Wahyu , Sonalitha Elta , Agustina Rini
Published: September 2021

Saat ini seluruh penduduk dunia berjuang melawan wabah covid-19. Cara yang efektif melawan covid adalah melawannya dengan meningkatkan imut tubuh. Salah satu cara meningkatkan imun tubuh adalah menjaga hidup sehat dengan kebiasaan berolahraga. Namun faktanya sebagian besar orang cenderung enggan berolahraga dengan berbagai alasan. Maka penelitian ini menganalisis bagaimana motivasi masyarakat dalam berolahraga selama pandemic Covid-19 dengan analisis core drive Octalysis sehingga dapat digali lebih jauh doronga-dorongan apa saja yang mungkin lemah dan yang kuat sehingga bisa dijadikan referensi bagi pihak-pihak yang berkepentingan untuk menyelenggarakan kegiatan olahraga yang lebih diminati. Hasil analisis menunjukkan bahwa kecenderungan masyarakat berolahraga semasa pandemic Covid-19 adalah termotivasi ingin menjaga kesehatan diri sendiri dan menginspirasi orang lain untuk hidup sehat. Sedangkan suasana kompetisi maupun kerjasama dalam olah raga tidak terlalu dibutuhkan karena masyarakat tidak terlalu termotivasi dari dua hal tersebut.
DISTORTIONS IN A PERSON'S BODY PERCEPTION AFTER PERFORMING DYNAMIC TASKS IN VIRTUAL REALITY
Authors:   Ryazan State Medical University, Yakovleva Natal'ya V. , Varlamov Andrei V. ,   Ryazan State Medical University
Published: September 2021

The article presents a study in the peculiarities of a person’s perception of the size of his own bodydistortion after a short-term immersion in a virtual environment and performing mobile purposeful tasks in it on behalf of a virtual character. The characteristic distortions in the perception of the sizes of the body parts most involved in the virtual activity in the direction of their increase were revealed. Thus, the study participants demonstrated characteristic statistically significant distortions in the perception of such parameters as neck length, shoulder length, hand length, body length, elbow joint width and head width. Distortions in the perception of the size of the upper half of the body (above the waist) correspond to those parts of the subjects’ bodies, the movement of which in space during the performance of the intra-environment task had the greatest functional significance. Immersion in virtual reality, mediated by a VR headset, leads to the formation of a specialvirtual environment perception in the recipient’s psyche. In this case, the perception of oneself also turns out to be tied to the perception of the controlled virtual character. Due to the uncertainty of its size and the blurring of the visual outlines, the image of one’s own body temporarily merges with the operatively formed image of the character, as a result of which an instrumental interiorization of its dimensions occurs. Thus, it is clearly demonstrated that the perception of the person’s body during the immersion in a virtual environment is connected to the nature of the performed movements.
THE RELATIONSHIP OF TRUST WITH INDICATORS OF CIVIC POSITION
Authors:   Russian State University for the Humanities, Akimova Margarita K. , Persiyantseva Svetlana V. ,   Russian State University for the Humanities,   Psychological Institute of Russian Academy of Education
Published: September 2021

The results of an empirical study of the relationship between citizenship and trust on a sample of students from three universities (N = 252) are presented in the article. A trusting relationship is based on goodwill, honesty and on the desire to understand, accept another person with all his individual characteristics. The civic position in the work is considered as the social civic activity of the individual, proceeding under the influence of the socio-cultural environment. This is a moral position that encourages a person to feel like a part of civil society, expressed in the presence of a person’s system of socially significant moral guidelines that determine his sense of duty and responsibility to society, his willingness to actively defend his rights and interests and therefore act for the benefit of the people, society. The concepts of “adoption of standards” and “civic identity” are revealed. Diagnostics, in the presented study, was carried out using the Questionnaire of Confidence Relationships, the Questionnaire of Civil Identity (two scales: attitude to the norms of civil society, active civic position); projective methodology “Civic identity” (the methodology studies the significant values of civil society on seven scales). It was found that the educational and regional characteristics of the studied groups of students have an impact on the level of trust and civic characteristics of Russian student youth.
Comparative analysis of matching pursuit algorithms for Kirchhoff migration on compressed data
Authors: Fajardo Carlos A. , Sánchez Fabián , Ramirez Ana B.
Published: September 2021

Currently, the amount of recorded data in a seismic survey is in the order of hundreds of Terabytes. The processing of such amount of data implies significant computational challenges. One of them is the I/O bottleneck between the main memory and the node memory. This bottleneck results from the fact that the disk memory access speed is thousands-fold slower than the processing speed of the co-processors (eg. GPUs). We propose a special Kirchhoff migration that develops the migration process over compressed data. The seismic data is compressed by using three well-known Matching Pursuit algorithms. Our approach seeks to reduce the number of memory accesses to the disk required by the Kirchhoff operator and to add more mathematical operations to the traditional Kirchhoff migration. Thus, we change slow operations (memory access) for fast operations (math operations). Experimental results show that the proposed method preserves, to a large extent, the seismic attributes of the image for a compression ratio up to 20:1.
Computational study of particle distribution development in a cold-flow laboratory scale downer reactor
Authors: López-Montoya Tatiana , Bustamante Carlos Andrés , Nieto-Londoño Cesar , Gómez-Velásquez Natalia
Published: September 2021

The use of downer reactors (gas-solid co-current downward flow) in the Fluid Catalytic cracking (FCC) process for the upgrading of heavy crude oil into more valuable products has gradually become more common in the last decades. This kind of reactor is characterized by having homogeneous axial and radial flow structures, no back mixing, and shorter residence times as compared with the riser reactor type. Although downer reactors were introduced a long time ago, available information in literature about the multiphase hydrodynamic behavior at FCC industrial scale is scarce. Therefore, it is necessary to conduct experimental and computational studies to enhance the understanding of the hydrodynamics of two-phase co-current downward flow. The Computational Fluids Dynamics (CFD) software, Ansys Fluent, is used to study two-dimensional gas (air) and solid (catalyst particle) flow in a downer section of a cold-flow circulation fluidized bed (CFB) system at a laboratory scale. The implemented computational model is validated by comparing numerical results for solid velocity and volume fraction with measurements carried out on a CFB system using a fiber-optic probe laser velocimeter. According to numerical results obtained for different gas velocity and solid flux, flow development cannot only be estimated by considering solid axial velocity changes along the reactor; it is also necessary to take into account solid volume fraction axial variations as radial profiles can change even when velocity profiles are developed.
Mass balance of Neogene sediments in the Colombia basin relationship with the evolution of the Magdalena and Cauca River basins
Authors: López- Ramos Eduardo , Rincon Martinez Daniel , Moreno Gómez Nestor , Gómez Gutierrez Pedro D.
Published: September 2021

The Colombia basin contains large volumes of sediment accumulated during the last 17 My. The use of isochore maps, exploratory wells, micropaleontological and geochronological dates has enabled us to estimate the volumes of sediment and accumulation rates in this basin. The analysis of source of sediments and exhumation data from the Northern Andes of South America led to the definition of areas and thicknesses of material eroded during the Neogene - Quaternary, to obtain volumes or material eroded from the continent that can be correlated with sediment volumes accumulated in the Colombia Basin. The analyzed sediment volumes suggest that during the last 17 My ~72.06x1015 Tons accumulated in the Colombia Basin, while ~ 7.16x1013 Tons accumulated in the continental catchment areas. The sedimentation in the Colombian Basin has occurred at variable rates, with values ranging from 55 MTons/My to 295 MTons/My, with a peak of 803 MTons/My in the early Pleistocene (between 2.4 and 2.2 Ma). The evaluation between the total volumes of sediment accumulated in the offshore and onshore, suggests that in the continental part of the basin less than 4% of the total volume of eroded sediment is trapped and, therefore, the behavior of the accumulation rates calculated in the offshore directly reflect the relief evolution of South America’s Northern Andes. It seems, at large, that the lithospheric convergence rates and subduction angle (South America vs Nazca and Meso Atlantic opening) have controlled the regional exhumation of the Northern Andes, with the exception of the Pleistocene high sedimentation event, which seems to coincide with local events such as the collision of the Panama Arch against Western Antioquia. It may be concluded that thanks to this collision, drainage systems such as those of the Magdalena and Cauca rivers were modified, which resulted in the formation of the Magdalena Submarine Fan.
Prinsip-Prinsip Perjanjian Muamalat dalam Hukum Perbankan Syariah di Indonesia
Authors: Faisal Faisal
Published: September 2021

According to the practice of Islamic banking principles, a bank should have muamalat agreement including the principle of deposit or deposits (depository/al-wadi'ah), the principle of profit sharing (profit-sharing), purchase (sale and purchase), leases (operational and financial lease lease), and services (fee-based services). Legal agreement adheres to several principles, including the principle of the freedom of an agreement (the sense of autonomy), the principle of adjustments will, and the principle of trust. In addition, there is also the principle of binding force, the principle of legal equality, the principle of balance, the principle of legal certainty, moral principles, merit principle, and the principle of habit.
Lelang Jabatan dalam Sistem Hukum di Indonesia
Authors: Sari Elidar
Published: September 2021

The case of official positional auction under Indonesia legal system is not yet determined hence on this case, the civil servant regulation is adopted as a reference on goverment organization. Therefore, the government body or state officials may consider any policy in order to fullfil the public demand. Indonesian officials have right to act based on Fress Ermessen’s principle which can provides the freedom for authorized party to make decision as long as it is still on the track and does not overreach legal procedure. Consequently, the official positional auction is considered as a policy that belong to all state officials as long as it does not againts the law.
Tipologi Korupsi Serta Penanganan yang Berkepastian Hukum dan Keadilan
Authors: Yusrizal Yusrizal
Published: September 2021

The concept of state law (rechtstaat) relating to corruption cases has to be conducted by implementing law enforcement, law certainty, and justice. Any kind of policy in relation to corruption eradication has to be done based on the application of legislation. The rule of legal officers in eradicating corruption is highly influenced by the integrity of morality and personal ethics (the maturnity of spiritual intelligence) by having good understanding on corruption eradication which is very significant in making a decision in relation to corruptor.
Pengaturan Perlindungan Hukum Terhadap Pengguna Jasa Transportasi di Darat atas Kehilangan dan Kerusakan Barang Kiriman
Authors: Fatahillah Fatahillah
Published: September 2021

Under the provisions of law number 22 of 2009 on traffic and road transport in article 193 states the responsibility of transport companies losses. Article 193 mentions the liability rules on compensation of corporate transportation. In the implementation of the transport was not immune from problems, such as broken, lost and late to the purpose it is due to the negligence of the transport or due to circumstances unforeseen for goods shipped to the detriment of the shipper, or may be carrying less attention to security and safety in the transport goods. In the case of dispute resolution to be taken as a result of damage and loss of goods to get right back to efforts to produce a consensus agreement between the parties. The completion of the deliberation will usually produce an agreement with the results of each of the parties mutually beneficial in order to maintain the good name of company transport services and service users are not unduly disadvantaged.
Dwilogi Interpretasi dalam Dominasi Pembagian Harta Ber-sama: Telaah atas Putusan Mahkamah Syar’iyah Lhoksukon Nomor 168/pdt.g/2014/ms-lsk
Authors: Aksa Fauzah Nur , Maulia Muhammad Ikbal
Published: September 2021

Studi ini hendak menjawab sebuah pertanyaan mengapa terdapat problem yuridis, sosiolo-gis dan bahkan epistemologis dalam polemik harta bersama pasca perceraian? Polemik tersebut dipecah dalam putusan Mahkamah Syar’iyah Nomor 168/Pdt.G/2014/MS-Lsk. Un-tuk menjawabnya, secara kualitatif, studi ini memanfaatkan pendekatan yuridis normatif yang disandarkan pada norma perundang-undangan. Dua model interpretasi ditampilkan sebagai objek formal, sekaligus juga objek material yang dioperasikan dalam rangka mela-hirkan putusan tersebut. Teori Ronald Dworkin dan Abi Ishaq asy-Syatibi juga dimanfaatkan untuk memperlihatkan titik-temu antara dua model interpretasi tersebut. Implikasi studi ini adalah bahwa dalam putusan Mahkamah Syar’iyah Nomor 168/Pdt.G/2014/MS-Lsk terdapat semacam dimensi epistemologis yang berpijak pada paradigm subtantif, yakni paradigma yang berpijak tidak hanya pada norma yuridis, tetapi juga kemaslahatan yang merupakan orientasi dari norma itu sendiri.
Editorial
Authors: Reusam Editorial
Published: September 2021

editorial
Analisis Yuridis Bahaya Narkotika bagi Kesehatan Masa Depan Generasi Muda
Authors: N Nasrianti , M Muhibbuddin
Published: September 2021

Abuse of Narcotics among the younger generation which can damage health and destroy the future of the younger generation and also the continuation of the future of the State then in legal considerations the birth of Law of the Republic of Indonesia Number 35 of 2009 concerning Narcotics is, to create a prosperous, just and prosperous Indonesian society that is evenly material and spiritual based on Pancasila and the 1945 Constitution of the Republic of Indonesia, the quality of Indonesia's human resources as one of the assets for national development needs to be continuously maintained and improved, including the degree of health; Therefore, to improve the health status of Indonesian human resources in the context of realizing the welfare of the people, it is necessary to make efforts to improve in the field of treatment and health services, among others by seeking the availability of certain types of Narcotics which are urgently needed as drugs and to prevent and eradicate the dangers of abuse and illicit Narcotics trafficking and Narcotics Precursor. The method used in this research is a qualitative normative juridical research method, namely a research method that refers to the legal norms contained in legislation. The conclusion of Articles 18 and 19 of Law of the Republic of Indonesia Number 36 of 2009 concerning Health, states that the Government is responsible for empowering and encouraging the active role of the community in all forms of health efforts, and the Government is responsible for the availability of all forms of quality, safe health efforts.  efficient, and affordable.
Urgensi Persetujuan Anak sebagai Syarat Poligami (Perspektif Undang-Undang Perkawinan dan Hak Asasi Manusia
Authors: Rasyid Muhammad , Arianti Mega
Published: September 2021

The concept of state law (rechtstaat) relating to corruption case has to be conducted by implementing law enforcement, law certainty, and justice.  Any kind of policy in relation with corruption eradication has tobe done based on the application of legislation.  The rule of legal officers  in eradicating corruption is highly influenced by integrity of morality and personal ethic (the maturnity of spiritual intelligence) by having good understanding on corruption eradication which is very significance in making decision in relation with corruptor.
KAJIAN HUKUM TERHADAP PENGELOLAAN ASET DAERAH
Authors: Basri Hasan
Published: September 2021

Regional property (BMD) can be obtained from apbd or other legitimate acquisitions and become regional wealth. State wealth in ministries / institutions / local governments become the authority and responsibility of ministries / institutions / local governments. But in the course of regional asset management sometimes also poses problems. Whereas well-managed regional assets will have a strategic role in supporting regional budget revenues. Bmd utilization applies to BMD located in the user of the goods, as well as who manages the goods. The existence of provisions, ensuring the process of utilization of BMD can run in an orderly, directed, fair, accountable, to realize efficient, effective, and optimal bmd management therefore regional asset management needs to be established and implementation based on the provisions of applicable laws and regulations. There should be a new mindset in the management of state assets so that not only just to record also list its fair value in the government financial report (LKPP), there should also be new thinking on how to optimize the management of state assets to be more optimal. The purpose of this writing is to review from the legal aspects regarding the management of regional assets. The research method used in this writing is done with literature studies. The approach used in this study is the approach of legislation and conceptual approach. The data source in this paper uses secondary legal material in the form of all publications about which are not official documents.
Healthcare in the smartphone: the situation in Russia
Authors:   «K-SkAI», Gusev A.V. ,   Moscow, Russia, Ivshin A.A. ,   Petrozavodsk State University, Russia, Vladzymyrskyy A.V. ,   State Budget-Funded Health Care Institution of the City of Moscow «Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department»
Published: September 2021

The purpose of the study was to analyze the popularity of mobile applications for health care in Russia. Material and methods. The app stores «App Store» of Apple and «Google Play Store» of Google were studied for comparative analysis. In case of The App Store we analyzed the categories «Medicine and Health and Fitness», in the Google Play Store – the categories «Medicine», «Motherhood and Childhood» and «Health and Fitness». The total amount of applications was 231. The reviewed applications were grouped into several groups and ranked in descending order of popularity. Results. The most popular applications by the number of downloads were applications from the group «Fitness and healthy lifestyle»: by individual positions – more than 1,2 billion. installations. On the second place was the group «Women's Health» with more than 285 million installations. The highest ratings of applications in the context of groups were received by services related to pregnancy control, evaluation of fetal and child development, as well as services for determining the symptoms of diseases. Conclusions. Thus, the most popular content for health care is the analysis of physical activity, regular diagnostics of the state of the body, monitoring of women's health indicators and monitoring the course of pregnancy, children's health.
Broccoli consumption attenuates inflammation and modulates gut microbiome composition and gut integrity-related factors in mice fed with a high-fat high-cholesterol diet
Authors: Zandani Gil , Anavi-Cohen Sarit , Sela Noa , Nyska Abraham , Madar Zecharia
Published: September 2021

Background: Nonalcoholic fatty-liver disease (NAFLD) is a global health problem associated with gut dysbiosis and intestinal permeability. Broccoli is a natural source of bioactive phytochemicals, characterized by health-promoting properties.

Objective: This study evaluated the effect of broccoli florets and stalks on liver fat accumulation, inflammation, gut microbiome, and intestinal barrier integrity.

Design: Male C57BL/6J mice (n = 32, 8-week-old) were fed with a high-fat high-cholesterol diet (HFCD) with/without 15% broccoli (florets or stalks) for 7 weeks. Liver damage was evaluated by changes in glucose response and histological and biochemical parameters. Protein and gene expressions related to liver inflammation were examined. The effect of broccoli on microbiota population together with genes related to barrier integrity in the gut was investigated.

Results: Dietary broccoli improved the glycemic response assessed by oral glucose tolerance test (OGTT). Histological evaluation showed no change in hepatic steatosis. Broccoli consumption also attenuated inflammation as revealed by lower inducible nitric oxide synthase (iNOS) and serum amyloid A1 (SAA1) expression levels in broccoli-supplemented groups. Gut microbiota analysis demonstrated elevated Acidifaciens and reduced Mucispirillum schaedleri abundance in the stalks group, whereas Proteobacteria strains abundance was increased in the florets group. Gut integrity remained unchanged.

Conclusion: Broccoli supplementation improves glucose tolerance, attenuates liver inflammation, and alters microbial composition, but does not affect gut integrity. This research provides new evidence on the effects of dietary broccoli under HFCD.
Diophantine approximation with the constant right-hand side of inequalities on short intervals
Authors: Bernik V. I. , Vasilyev D. V. , Zasimovich E. V.
Published: September 2021

In the metric theory of Diophantine approximations, one of the main problems leading to exact characteristics in the classifications of Mahler and Koksma is to estimate the Lebesgue measure of the points x ∈ B ⊂ I from the interval I such as the inequality | P (x) | < Q-w, w > n, Q >1 for the polynomials P(x) ∈ Z[x], deg P ≤ n, H(P) ≤Q is satisfied. The methods of obtaining estimates are different at different intervals of w change. In this article, at w > n +1 we get the estimate µ B< c1(n) Q – (w-1/n). The best estimate to date was c2(n) Q –(w- n/n).
Sorption of peptides and amino acids by ion exchangers
Authors: Kuvaeva Z. I. , Karankevich E. G.
Published: September 2021

Sorbtion of dipeptides leucylisoleucine, threonylthreonine and their monomeric amino acids leucine and threonine by anionite AV-17 and cationite KU-2-8 in a wide range of equilibrium concentrations has been studied. It was shown that the presence of hydrophilic OH-groups in the threonine molecule promotes superequivalent sorbtion of threonine on the cation exchanger. The presence of an OH-groups in the side chein of the dipeptide practically does not affect the sorbtion an KU-2-8. Sorbtion of dipeptides on AV-17-8 is higher in comparison with their monomeric amino acids.
Synthesis of S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole
Authors: Lopatik D. V. , Kuvaeva Z. I. , Naidenov V. E. , Bondareva O. M. , Tychinskaya L. Yu.
Published: September 2021

Condensed indole derivatives of the 1,2,4-triazino[5,6-b]indole group show high biological activity and are of interest for the development of pharmaceuticals that have antihypoxic and antisurditant effects. By S-aminoalkylation reactions on a thione group, S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole-3-thione that were subject to hydrobromination in order to obtain the form of hydrobromides were synthesized, isolated and characterized.
Features of the synthesis of highly dispersed alumophosphates AlPO4·nH2O
Authors: Eshchenko L. S. , Paniatouski A. V.
Published: September 2021

Aluminum orthophosphate of the composition AlPO4·2H2O with a monoclinic structure identical to the structure of the natural mineral metavariscite was obtained by condensation method during hydrothermal treatment of alumophosphate solutions with a concentration (g/l) of Al2O3 90 – 115, P2O5 340 – 440 in the temperature range 95–99 °C. For the first time, the role of aging of the alumophosphate system in shortening of the induction period, simultaneous nucleation of primary particles in the entire volume of the solution and the formation of a pasty product with a predominant particle size of 1–10 μm, in contrast to 30–50 μm, characteristic of a fine-crystalline product obtained without aging of the solution, is established. It is shown that pasty AlPO4·2H2O, in comparison with fine-crystalline, is hardly soluble in HCl even under prolonged heating. The influence of P2O5 content in the alumophosphate solution, the conditions of its aging and the duration of hydrothermal treatment on the particle size distribution for synthesized aluminum orthophosphates have been established. Anhydrous alumophosphate obtained by dehydration of pasty AlPO4·2H2O in the temperature range of 150–200 °C with subsequent heat treatment at 900 °C is readily soluble in acids, and the predominant particle size is 5–13 μm.
Preparation of the heat-resistant superhydrophobic coating with a nanostructured finish layer based on a suspension of silicon dioxide in a fluorinated film-former and its properties
Authors: Koshevar V. D. , Shkadretsova V. G. , Pismenskaya A. S.
Published: September 2021

The processes of obtaining compositions based on organosilicon resin for a heat-resistant coating of accelerated drying, as well as its hydrophobization by creating an isotropic nano-microstructure on the surface, are studied. It is shown that the chemical nature, the content of the ingredients and the thickness of the coatings have the greatest influence on the physicochemical properties of heat-resistant coatings. The methods of obtaining a composition for heat-resistant coatings using a dissolver and a bead mill in various modes of operation were studied, which allowed us to develop a technological process for manufacturing heat-resistant paint and varnish material. The composition and technology of obtaining a final hydrophobic layer based on a suspension of aerosil HDK 12H and carbon nanoparticles in a fluorine-containing varnish LF 32LN was developed in order to obtain a complex heat-resistant, superhydrophobic and anticorrosive coating for the protection of metal products and its properties were investigated.
Chemical modification of different compounds with nitrogen-containing heterocycles
Authors: Akishina E. A. , Dikusar Е. А.
Published: September 2021

Heterocyclic compounds have an extremely important practical application, since many heterocycles are the basis of the most valuable medicinal substances, both natural (vitamins, enzymes, alkaloids, etc.) and synthetic biologically active compounds. The work mainly considers the most relevant directions for various purposes drugs search by modifying known bioactive natural, organoelement and framework compounds with 1,2-azole, oxazole, oxadiazole, thiazole, triazole, pyridine, pyrimidine heterocycles over the past 10 years. Chemical modification makes it possible to increase the water solubility of the compounds, which is important when choosing the pathways for the most rational drug introduction into the body, to reduce the toxicity of the corresponding substances, to increase the breadth of the therapeutic action, and also to give new valuable medicinal properties, thus significantly expanding their application in medicine and agriculture.
Energy metabolism and redox status of the glutathione system in experimental brain ischemia and its correction by metabolic neuroprotectors
Authors: Titko O. V. , Lukiyenko E. P. , Raduta E. F. , Semenovich D. S. , Vasilevich A. A. , Poleshuk A. I. , Moiseenok А. G. , Kanunnikova N. P.
Published: September 2021

The changes in the parameters of oxidative stress, energy metabolism, and redox potential of the glutathione system in the rat brain following cerebral ischemia were studied. To correct metabolic disorders, the pantothenic acid derivatives were used in combination with precursors of glutathione biosynthesis and selenium substances.Cerebral ischemia was modeled by ligating the both common carotid arteries in rats for 2 h. Drugs were administered i.p. in the following doses: panthenol – 400 mg/kg, N-acetylcysteine – 150, nanoselen – 1 mg/kg, three times: 1 h before ligation of the carotid arteries, at the time of ligation and 1 hour after ligation. We showed that the development of oxidative stress caused by ischemia is accompanied by the changes in the parameters of energy metabolism and the pentose phosphate pathway in the cerebral hemispheres. Simultaneously, there are a decrease in the GSH level, an increase in the GSSG content, a decrease in the GSH/GSSG ratio, and the activation of enzymes of redox transformations of glutathione.The redox potential of the glutathione system decreases and shifts towards oxidation, while the level of S-glutathionylated proteins increases. Thus, the value of the GSH/GSSG ratio and the protein glutathionylation intensity are the sensitive indicators of the redox potential in the brain tissue and can be used as markers of the extent of changes in the redox balance. The panthenol injection to animals leads to a decrease in the content of free radical oxidation products, violations of oxidative phosphorylation and restoration of thiol-disulfide balance in the brain. When panthenol is administered together with N-acetylcysteine and nanoselen, the corrective effect of panthenol is enhanced.