bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-Term Patient-Reported Outcomes in Internationally Adopted Children with Cleft Lip and Palate
Authors: Salinero Lauren K. , Ahluwalia Vinayak S. , Barrero Carlos E. , Wagner Connor S. , Pontell Matthew E. , Magee Leanne , Low David W. , Jackson Oksana A. , Napoli Joseph A. , Bartlett Scott P. , Swanson Jordan , Taylor Jesse A.
Published: August 2023

Objective

To compare patient-reported outcomes (PROs) in internationally adopted patients with cleft lip and palate to those in non-adopted peers.

Design

Cross-sectional study.

Setting

Multidisciplinary cleft team at tertiary care hospital.

Patients

Patients aged ≥ 8 with cleft lip and palate attending routine cleft team evaluations September 2021 - September 2022.

Main Outcome Measure

CLEFT-Q PRO scores.

Results

Sixty-four internationally adopted patients and 113 non-adopted patients with a mean age of 13 years were included. Compared to non-adopted peers, adopted patients demonstrated worse satisfaction with face appearance (mean 59 vs. 66, p = .044), speech function (mean 69 vs. 78, p = .005), and speech distress (mean 80 vs. 84, p = .032). No significant differences were observed on the nose, nostrils, teeth, lips, lip scar, jaws, psychological function, or social function scales ( p > .05). Objective clinical evaluation corroborated these findings, with adopted patients demonstrating worse Pittsburgh Weighted Speech scores (mean 3.0 vs 1.9, p = .027) and greater incidence of articulation errors (64% vs 46%, p = .021). No significant differences were observed in rates of mood, anxiety, or behavior concerns identified on psychosocial assessment ( p = .764). Among adopted patients, undergoing palatoplasty prior to adoption was associated with worse satisfaction with speech, appearance, school, and social function ( p < .05).

Conclusions

Patient-reported outcomes among internationally adopted adolescents and young adults with cleft lip and palate show slightly lower satisfaction with facial appearance and speech but otherwise demonstrate similar results to non-adopted peers on most appearance and psychosocial measures. PRO data correlated well with objective speech assessment and did not portend worse psychosocial function.
Sino-US Green Finance Cooperation (2016–2022)—An Empirical Analysis Based on Texts
Authors: Wang Wenjing , He Taiyi , Lin Jingcheng , Zhao Haoxiang , Qin Zezheng , Dai Kunhao
Published: August 2023

Green finance cooperation is an organic component of international cooperation among the globalization, but few studies focused on the status of green finance cooperation. Previous studies have confirmed the value of green finance cooperation within countries for green development, laying the foundation for initiating discussions on green finance cooperation between countries. This paper uses quantitative methods such as word frequency statistical analysis, visualization cloud map, and semantic network analysis to analyze the development process of Sino-US green finance cooperation on the basis of selected green finance cooperation texts. The results show that multi-dimensional parties in Sino-US green finance cooperation play a role in promoting the cooperation process and resolving differences in cooperation cognition. Secondly, the auxiliary elements of Sino-US green finance cooperation have achieved value mobilization and effective integration. Thirdly, the development effect of Sino-US green finance cooperation has a relatively sensitive response to external shocks represented by political factors.
Outcomes of 4-factor Prothrombin Complex Concentrate in Patients With Liver Disease and Nonvitamin K Antagonist-Related Coagulopathy: A Retrospective Study
Authors: Dodhiawala Paarth B. , Pribyl Kyle , Larson Jared , Vakayil Victor , Chandrashekar Malavika , Lord Amanda , Welbig Julie , Zantek Nicole D. , Martin David , Harmon James V.
Published: August 2023

The administration of 4-factor prothrombin complex concentrate (4F-PCC) has expanded beyond its Food and Drug Administration (FDA)-approved indication for the emergent reversal of vitamin K antagonists (VKAs). Therefore, this study aimed to evaluate the risks and benefits associated with the expanded use of 4F-PCC. We conducted a single-center retrospective review of 4F-PCC administrations at our university hospital. Of the 159 patients who received 4F-PCC, 76% (n = 121) and 24% (n = 38) received it for the FDA-approved indication in the vitamin K-related coagulopathy (VKA) group and for expanded use in the nonvitamin K-related coagulopathy (nVKA) group, respectively. The expanded use of 4F-PCC was associated with a less robust reduction in the international normalized ratio (INR) (INR of −0.7 ± 1.3 vs INR of −1.6 ± 1.8, P = .002), and fewer patients in the nVKA group achieved a postadministration INR of less than1.5 (11% vs 79%, P = .001) than those in the VKA group. Furthermore, the 30-day mortality rate was significantly higher in the nVKA cohort than in the VKA cohort (42% vs 20%, P = .04). Notably, based on our data, underlying differences in the patient’s comorbidities, particularly advanced liver disease, may have contributed to the observed outcome variations, including mortality rate. Therefore, factors, including comorbidities and the underlying etiology of coagulopathy, should be considered when deciding on the expanded use of 4F-PCC. Further research is needed to better understand the potential risks and benefits of 4F-PCC in expanded use scenarios, and the clinical decision to use 4F-PCC outside its FDA-approved indication should be made carefully, considering this information.
Information and communication technologies in physical education: Exploring the association between role modeling and digital literacy
Authors: Wohlfart Olivia , Mödinger Moritz , Wagner Ingo
Published: August 2023

Teacher educators should serve as role models in terms of information and communication technologies (ICTs) use to promote digital literacy of future teachers. To analyze the association between role modeling by teacher educators and preservice teachers’ digital literacy and ICT integration intention in their classrooms, 185 physical education (PE) preservice teachers in the German federal state of Baden-Württemberg completed an online questionnaire of self-assessed technological, pedagogical, and content knowledge (TPACK) and ICT integration. The results of regression models revealed a positive association between content knowledge and pedagogical knowledge (PK) and overall intent to integrate ICT into teaching. The results further indicated that the impact of role modeling on preservice teachers varies depending on the chosen ICT. In this paper, we discuss the implications of these findings for higher education in general and for PE in particular.
Comparing Lookback Periods to Ascertain Alzheimer’s Disease and Related Dementias
Authors: Kunicki Zachary J. , Bayer Thomas , Jiang Lan , Bozzay Melanie L. , Quinn McKenzie J. , De Vito Alyssa N. , Emrani Sheina , Erqou Sebhat , McGeary John E. , Zullo Andrew R. , Duprey Matthew S. , Singh Mriganka , Primack Jennifer M. , Kelso Catherine M. , Wu Wen-Chih , Rudolph James L.
Published: August 2023

Claims data are a valuable resource for studying Alzheimer’s disease and related dementias (ADRD). Alzheimer’s disease and related dementias is often identified using a list of claims codes and a fixed lookback period of 3 years of data. However, a 1-year lookback or an approach using all-available lookback data could be beneficial based on different research questions. Thus, the purpose of this study was to compare 1-year and all-available lookback approaches to ascertaining ADRD compared to the standard 3-year approach. Using a cohort of Veterans hospitalized for heart failure (N = 373, 897), our results suggested high agreement (93% or greater) between the lookback periods. The 1-year lookback period had lower sensitivity (60%) and underestimated the prevalence of ADRD. These results suggest that 1-year and all-available lookback periods are viable approaches when using claims data.
Unity or Estrangement Under Crises? Perceived Resource Scarcity Moderates the Effect of a Common Threat on Intergroup Cooperation
Authors: Miao Xiaoyan , Liu Li , Dang Jianning , Wei Cong , Huang Lingling , Liu Zhen
Published: August 2023

Human history and recent empirical studies have documented many cases of human unity or estrangement during global crises. This reflects that a common threat may not always promote intergroup cooperation. An intriguing question arises: What determines the effect of a common threat on intergroup cooperation? In response, we proposed and tested the moderating role of perceived resource scarcity in the effect of a common threat on intergroup cooperation. We found that when perceived resource scarcity was low, common threats posed by pandemics (Studies 1 and 2) and earthquakes (Study 3) promoted intergroup cooperation in controlling outbreaks, building public medical systems, and reducing public resource depletion. However, the effect attenuated when perceived resource scarcity was high. The findings broaden our understanding of common threats and provide avenues to enhance intergroup cooperation in the face of interminable global crises.
“In Spite of the Storm, I Saw Bright Spots”: School Counselors Experiences During COVID-19
Authors: Goodman-Scott Emily , Perez Betsy M.
Published: August 2023

In spring 2022, we conducted a phenomenological investigation on the lived experiences of 12 U.S. school counselors during the COVID-19 global pandemic, triangulating individual interviews and participant drawings to gain a rich, thick, comprehensive account. We found that school counselors perceived their experiences during the pandemic as multifaceted and complex, composed of intertwining initial and ongoing challenges and growth or positives that emerged in the face of crisis and loss. Participants reported these findings across multiple areas of their lives: personal, professional, and at the K–12 educational/societal level. We discuss results within the lens of shared trauma and posttraumatic growth, providing implications for school counselors as they work within the current “new normal” and reverberating impacts of a global pandemic.
Transformational Leadership and Project Success: The Moderating Effect of Top Management Support
Authors: Fareed Muhammad Zeeshan , Su Qin , Abbas Naqvi Najam , Batool Rida , Aslam Muhammad Umer
Published: August 2023

Great attention has been paid to the projects’ success, which is the core of project management. It is not surprising that much research is being done in this area, as several factors contribute to the project’s success. However, the moderating effect of top management support (TMS) on the relationship between transformational leadership (TL) and project success (PS) has not been investigated before. This study aims to examine whether the relationship between a project manager’s transformational leadership and project success is moderated by top management support. This study uses a post-positivism philosophical objective to investigate the theoretical model. A cross-sectional time-lagged survey design was used to collect quantitative data. Data was collected using a structured questionnaire from 273 team members, project managers, and stakeholders working in Pakistan’s public sector. The factor and hierarchical regression analysis were used for analysis. Our results showed that TL and TMS significantly impacted project success. Moreover, we found that TMS moderates the relationship between TL and PS.
The Impact of Gender-affirming Surgeries on Suicide-related Outcomes: A Systematic Review
Authors: Marques Inês Rafael , Cagigal César Augusto Mendes , Ezzeddine Reem , Rema João Paulo Alvim Gonçalves Pinto , Cruz Filipa Andreia Lemos Novais Oliveira
Published: August 2023

Aims:

Being transgender has been linked to poor mental health indicators, especially those related to suicide. We aimed to review the impact of gender-affirming surgeries (GAS) on suicidal behavior in the transgender population.

Method:

An advanced search was conducted on PubMed until February 28, 2022, and a total of 11 studies were considered eligible. Data were extracted on the size of sample population, control group, type of procedure, means of assessment, duration of time between surgery and assessment, and suicide-related outcomes. The considered outcomes were suicidal ideation, suicide attempts, and death by suicide.

Results:

Five studies compared the same patients pre- and post-GAS, while six studies compared patients who underwent GAS with a group who did not. Overall, suicide-related outcomes were found to be less frequent in patients after GAS when compared to those same patients’ pre-GAS indicators. The two studies that used either the general population or matched age and sex controls found a much higher prevalence of suicide-related outcomes, specifically suicide attempts and death by suicide, in post-GAS patients than in control groups. However, the studies that compared the treatment groups with either patients in an earlier phase of the transition or those who desired but had not yet undergone surgery showed lower post-GAS suicide-related outcomes, including suicidal ideation and suicide attempts.

Conclusions:

Suicidal ideation was generally found to decrease post-GAS; results regarding suicide attempts were inconsistent, and there was insufficient data to draw any conclusion about the effects of GAS on death by suicide.
Cleistocalyx nervosum var. paniala Extract: Anti-acne, Anti-oxidant, Anti-inflammatory Activities and Safety for Cosmeceutical Applications
Authors:   Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand, Khammitham Tharadon , Leelapornpisid Pimporn ,   Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand,   Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand, Chansakaow Sunee ,   Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand, Leelapornpisid Warat ,   Department of Restorative Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand, Poomanee Worrapan ,   Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand,   Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand
Published: August 2023

This research aimed to investigate the biological activities and safety of extracts from Cleistocalyx nervosum var. paniala for anti-acne cosmeceutical and to determine total phenolic, flavonoid and anthocyanin contents and HPLC fingerprint. The extracts named as whole fruit extract (WF) and seed extract (SE), were macerated with 95% ethanol. Antibacterial effects against Cutibacterium acnes and Staphylococcus aureus were evaluated using agar diffusion, broth microdilution and time-kill kinetic assays. The results revealed that SE presented stronger antibacterial activities against C. acnes and S. aureus with inhibition zone of 22.74 ± 0.52 and 12.67 ± 0.15 mm, respectively. However, the MIC and MBC values were with 6.25 and 3.12 mg/ml for C. acnes and S. aureus, respectively, with a kill time of 2 and 4 h, respectively. SE showed higher phenolic and flavonoid contents compared with WF. In contrast, WF revealed higher anthocyanin content. According to HPLC analysis, ellagic acid was used as a marker. Additionally, anti-oxidant activity of the extracts was investigated by DPPH assay and inhibition on nitric oxide radicals. SE showed better activities with IC50 of 7.51 ± 0.40 and 25.47 ± 1.09 µg/ml, respectively. Therefore, SE was selected for testing with nitric oxide radical producing on RAW 264.7 cell lines which presented 22.99% inhibition. Moreover, SE showed no irritation on Hen's Egg Test Chorioallantoic Membrane. To conclude, SE from C. nervosum exerted stronger biological activities than WF. It also demonstrated a good potential concerning antibacterial on acne-related microorganisms, anti-oxidants, and anti-inflammatory activities. Therefore, it could be a promising bio-active compound to further develop into anti-acne cosmeceutical products. Keywords: Cleistocalyx nervosum, Acne vulgaris, Cutibacterium acnes, Anti-inflammatory activity
Risk factors for post-traumatic stress disorder among young and middle-aged cancer patients in the intensive care unit: A case-control study
Authors: Chen Lei , Wang Guo-Zhou , Chi Yuan-Yuan , Zhao Jing
Published: August 2023

Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.
Analysis of prognostic factors in patients with emergency sepsis
Authors: Ning Xian-Li , Shao Min
Published: August 2023

Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.
Clinicopathological study of malignant peripheral nerve sheath tumors in the head and neck: Case reports and review of literature
Authors: Li Long , Ma Xiao-Kun , Gao Yan , Wang Dian-Can , Dong Rong-Fang , Yan Jing , Zhang Ran
Published: August 2023

Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.
Parathyroid carcinoma: Three case reports
Authors: Shi Ce , Lu Ning , Yong Yan-Jie , Chu Hai-Di , Xia Ai-Jun
Published: August 2023

Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.
Median neuropathy after multiple punctures of the forearm for catheterization: A case report
Authors: Suzuki Tomoaki , Matsui Yuichiro , Momma Daisuke , Endo Takeshi , Iwasaki Norimasa
Published: August 2023

Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.
Novel COL4A3 synonymous mutation causes Alport syndrome coexistent with immunoglobulin A nephropathy in a woman: A case report
Authors: Chen Yu-Ting , Jiang Wen-Ze , Lu Ke-Da
Published: August 2023

Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.
Single omental metastasis of renal cell carcinoma after radical nephrectomy: A case report
Authors: Chung Jae-Wook , Kang Jun-Koo , Lee Eun Hye , Chun So Young , Ha Yun-Sok , Lee Jun Nyung , Kim Tae-Hwan , Kwon Tae Gyun , Yoon Ghil Suk
Published: August 2023

Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.
Synthesis of New Organotin(IV) N-methyl-N-benzyl Dithiocarbamate Compounds and Cytotoxicity assessment on Human Lung Carcinoma Cell Line (A549)
Authors: Abd Aziz Nurul Amalina , Jamaludin Nur Atiyah Nadhrah , Awang Normah , Kamaludin Nurul Farahana , Chan Kok Meng , Anuar Nur Najmi Mohamad
Published: August 2023

Using the In-situ method, the successful synthesis of dibutyltin(IV) N-methyl-N-benzyldithiocarbamate (Compound 1) and tricyclohexyltin(IV) N-methyl-N-benzyldithiocarbamate (Compound 2) was achieved. Both compounds were characterized by the CHNS elemental analysis, FTIR, NMR spectroscopies and X-ray crystallography study. The experimental CHNS values demonstrated good congruence with the CHNS’s theoretical values of the suggested formula structures. The key infrared absorbance peaks, νC—N) and νC—N), which were found between 1475–1481 cm–1 and 971–975 cm–1, respectively. The 13C chemical shift of carbon in the NCS2 group was observed in the range of 200.66–202.32 ppm. The crystal structure of Compound 1 shows the anisobidentate’s coordination mode between the central metal of the Sn atom and the dithiocarbamate ligands. Compound 1 and Compound 2 have shown great toxicity effects against carcinoma cells in the human lung (A549) with lower IC50 values of 0.80 µM and 2.77 µM, respectively.
Organic Geochemical Investigation of Crude oils from the Al Bayda Platform Area (Samah formation), Central Part of the Sirte Basin, Northern Libya
Authors: M. Faraj Musbah Abduljalil , M. Buna Musbah Ahmed , Asmeedah Garnasah Ahmed , Lamma Osama Asanousi , Saheed Ramadan Musbah
Published: August 2023

In this paper, the geochemical studies of API gravity, content of asphaltenes and gross compositions were performed on samples from two crude oils collected in the Al Bayda Platform Area (Samah formation), central part of the Sirte Basin. The results showed that the fraction of saturates is the dominant fraction in oils in comparison to aromatics and NSO components, with high API gravity and low content of asphaltenes which indicates that the oils are mature, generated from marine organic sources and that they can be classified as light crude oils. The aim of this study is to provide evidence about precursor of organic material, depositional environment, and maturity of the studied oils. Saturated hydrocarbons were analyzed by gas chromatography – mass spectrometry and gas chromatography – mass spectrometry – mass spectrometry technique. Results indicates that the oil samples are originating from high marine organic matter phytoplankton and algae, with few terrestrial inputs, reflecting that oils can be sourced from siliciclastic, possibly marine shales deposited in a clay-rich marine, deposited under intermediate conditions with high maturity. All results showed that the oil samples are similar in their characteristics, likely due to the migration pathways in the same region.
Role of Alizarin red-S-NaLS-Ascorbic acid System in Solar Photogalvanic Performance and Storage
Authors: Ram Birama , Lalita Jai , Genwa K.R.
Published: August 2023

The aim of research work was to convert and store the photogalvanic energy by alizarin red-s - NaLS - ascorbic acid. The photogalvanic cells are based on photoelectrochemical nature. This study is better over reductant system i.e., ascorbic acid. The obtained results are comparatively better for sustainable application. M/5000 solution of alizarin red-S, M/1000 solution of NaLS and M/1000 solution of ascorbic acid were used for experimental observation. The fill factor (FF) and conversion efficiency (CE) were calculated for alizarin red-S - NaLS - ascorbic acid system and results were 0.2731 and 1.8970 %, respectively. The electrical outcome was relevant to power, open- circuit voltage, and short circuit current for alizarin red-S - NaLS - ascorbic acid system in solar photogalvanic performance and storage. These results are 197.29 µW, 1075 mV, 672 µA, respectively. The photo-excitation of alizarin red-S molecules was studied in solar performance and storage for photoelectrochemical process.
Elevated Polyurethane Coated Polybenzoxaine Intercalated ZrO2 Nanocomposites: A New Frontier for Protective Coatings in Various Disciplines
Authors: Nataraj Valarmathi , Mani Sivaraju , Palaniyappan Mohanambal
Published: August 2023

The suggested polybenzoxine@ZrO2 nanocomposite surfaces' excellent anticorrosive feature opens in novel avenues for the creation of high action non-corrosive coatings for variety of sectors. The conclusion of mild steel was decreased as a consequence of the accumulation of PBz-wrapped ZrO2 nanoparticles to the PU coating because they prevented charge transfer at the metal/electrolyte interface. TGA proves that the copolymer matrix's thermodynamic endurance has risen as a result of the ZrO2 NP addition. EIS findings demonstrated coated PU/PBz@ZrO2 nanoparticles' exceptional corrosion prevention ability. According to the results of the TEM/EDX analysis, the corrosion products that form at the metal electrolyte interface function as an inactive coating that slows down the breakdown of metals. Because ZrO2 and PBz work together in harmony, adding polybenzoxazine enhanced ZrO2 nanoparticles to the polyurethane film strengthens its barrier and mechanical features.
Synthesis, Characterization and Antimicrobial Evaluation of Amino acid Derivatives of 1,3,4-Oxadiazole
Authors: Vaishnav Yudhishthir , Rajpurohit Sangeeta , Vyas Kamalkant
Published: August 2023

Several novel 1,3,4-oxadiazole compounds were synthesized for this investigation. NMR and IR spectrum analysis as well as carbon, hydrogen, and nitrogen studies were used to characterize these novel synthesized compounds. Antibacterial and antifungal tests were conducted on all of the newly synthesized compounds. Staphylococcus aureus and Bacillus subtilis, both Gram +ve bacteria, and Escherichia coli and Pseudomonas aureginosa, both Gram -ve bacteria, were utilised in antibacterial studies. Aspergillus niger and Candida albicans were used to test the efficacy of antifungal treatments. Ciprofloxacin and fluconazole were utilized as reference medications in antibacterial and antifungal research, respectively. The inhibitory effects ranged from mild to strong across all of the substances. The results of the screenings showed that several of the compounds had stronger antibacterial and antifungal properties than the standard medicines.
Impedance Analysis on Interaction Between Ofloxacin and Supported Bilayer Lipid Membrane(BLM)
Authors: Poornima K. , Sankar A. , Rameshkumar S. , Periasamy M.
Published: August 2023

Using the EIS method (Electrochemical Impedance Spectroscopy), the interaction of the BLM (lipid bilayer membrane) system with Ofloxacin in NaCl bath solutions was studied. The BLM system shows electrical properties and stability, which mainly depend on the concentration of the sodium chloride bath solution. The stability of the BLM system increased due to the increase in the concentration of NaCl. On the surface of BLM, a fixing impact has been created due to the cations. The Ofloxacin atoms get divided into the BLM stage and display the fluidization impact. The resistance of the membrane decreases with the concentration of Ofloxacin. To identify Ofloxacin in the arrangement, an impedimetric sensor was created. The level of Ofloxacin detected mainly depends on the sodium chloride concentration present in the bath solution.
The Oxidative Transformation of Substituted Mandelic acids by Ethylenediammonium Dichromate in AcOH-H2 O medium: (A Kinetic Study)
Authors: Kharetiya Priyanka , Panday Dinesh
Published: August 2023

The oxidation of Mandelic Acids to the corresponding oxoacids with ethylenediammonium dichromate (EDDC) in aqueous acetic acid has been studied. The reaction is first order with respect to [EDDC] and less than two order observed for Mandelic acids and [H+]. The oxidation of α-deuteriomandelic acid shows the presence of a primary kinetic isotope effect (kH/kD = 6.01 at 298K). The reaction has been found to be catalyzed by [H+] ions. The various thermodynamic parameters for the oxidation have been reported and discussed along with the validity of the isokinetic relationship. With a negative reaction constant (ρ), the reaction displayed a strong correlation with the Hammett σ values. All of the chosen Mandelic acids are oxidised by the same process, according to the Exner plot.
Sunlight Induced Photogalvanics for Conversion and Storage of Solar Energy: Coomassie Brilliant Blue-Isopropyl Alcohol-Sodium Lauryl Sulphate System
Authors: Sharma Pratibha , Rathore Jayshree
Published: August 2023

Research plan was proposed for systematic observation with scientific way in the solar cell field of photogalvanics. It was analysis of experimental work under the solar energy output. The study of photogalvanic was done for solar energy conversion and storage by using of dye as Coomassie Brilliant Blue CBB), reductant as Isopropyl alcohol (IA), and surfactant as Sodium Lauryl Sulphate (SLS). For this purpose, a specially designed H shaped photogalvanic system was used under investigation for innovative results. Different scientific instruments were used for methodology set up i.e., pH meter (digital), microammeter, and 200 Wt. W bulb (As light source), multi-meter, two electrodes (one was calomel and another was Pt), carbon pot 450 k, resistance key. Findings: The photogalvanic cells were studied using different parameters via photo potential, photocurrent, conversion efficiency, fill factor and cell performance. The above values are as follows: 533.0 mV, 201.0 uA, 0.8796 %, 0.3066 and 114.0 minutes. These cells were studied for the good results in solar energy field. Novelty: The observed results are very good over previously obtained results with respect to Coomassie brilliant blue, reductant as Isopropyl alcohol, and surfactant as sodium lauryl sulphate system.
"When I Think of It I Awfully Dread It": Conceptualizing Childbirth Pain in Early America
Authors: Doyle Nora
Published: August 2023

summary: The emergence of obstetric anesthesia in the second half of the nineteenth century was preceded by a transformation in the medical conceptualization of women's pain. In the eighteenth and early nineteenth centuries, physicians described pain in physiological terms as natural and unproblematic, but in the second half of the nineteenth century they adopted a newly emotional language that emphasized women's subjective experiences of suffering. Middle-class and elite white women shaped this transition by insisting that their physical and emotional anguish was extreme. Women's attitudes, combined with a growing perception that sensibility to pain was a marker of "civilization," pushed physicians to view suffering as real and problematic. As they began to depict pain relief as an urgent medical concern, physicians envisioned refined white women as the primary beneficiaries of their new technology; this perspective paved the way for the increasingly routine use of anesthesia for middle-class and elite white women.
Vaccination, Dispossession, and the Indigenous Interior
Authors: Archer Seth
Published: August 2023

summary: This article explores a poorly understood smallpox vaccination campaign targeting Native Americans in the 1830s. While previous scholars have addressed the motivations of U.S. officials in launching the campaign, the author focuses on Indigenous people's interest in disease prevention and their reception of American physicians and vaccine technology across a broad swath of North America. Resistance to vaccination was not uncommon among Native people, yet many were open to the new form of preventive medicine, including some who sought it out and others who demanded it from the government. Departing from a scholarly consensus, the author argues, first, that the federal vaccination program should be viewed as a successful public health intervention in Indian Country and, second, that this success owed to Indigenous nations' desire for protection against a singularly destructive pathogen.
We Need Diverse Fanfiction Studies: On Shipping Fanfiction and CYA Literature
Authors: Kidd Kenneth
Published: August 2023

Abstract: While often celebrated as a space for diverse representation and engagement, fanfiction, including fanfiction based on children’s and young adult narrative, is not necessarily progressive and tends to reflect the representational politics of mainstream media and publishing. Fanfiction generally favors and develops around high-profile book and media franchises and repeats as much as challenges their ideological tendencies. Meanwhile, fan material about lesser-known titles remains largely unstudied despite a wealth of data on fanfiction sites and platforms such as Archive of Our Own (AO3) and Fanfiction.net. This article argues that fanfiction studies, like children’s literature studies and children’s literature itself, needs to become more diverse in its topics, its methods, and its ethical commitments. It recommends structural and comparative approaches to children’s literature-based fanfiction, including the study of its dynamics of canonization and circulation, which both resemble and diverge from those of source texts or “canon.” One model discussed is Emer O’Sullivan’s Comparative Children’s Literature, which might be adapted to comparative fanfiction work. The article also attends to the various feedback loops between canon and its fanfiction, underscoring, for instance, how some fanfiction has been legitimized as literature even as some novels about fanfiction have inspired fanfiction, in turn.
Migration and Empathy
Authors: Cheng Vincent J.
Published: August 2023

ABSTRACT: This essay is a meditation on the contemporary migration and refugee crisis, the history of Irish emigration, and Joyce's awareness and treatment of such issues. It begins by discussing the official definitiions and political impacts of the terms "migrant" and "refugee," followed by an investigation of the risks and often tragic consequences of attempts to "migrate" to a better life (both nowadays and in the past). The second half of the essay explores how Joyce's texts treat such issues and their relationship to the politics and complexities of our contemporary moment—leading to an argument about the need for identificatory empathy or what I call "reverse parallax."
Long-Term Struggles for Land and Related Services: Egalitarian Local Authority in the Eastern Cape’s Border-Kei Region from the Mid-1980s to 2010.
Authors: Wotshela Luvuyo
Published: August 2023

ABSTRACT: For many within Bantustans during the epoch of late apartheid, the struggle for egalitarian local authority, and provision of services, innately linked to those for residential and other land needs. Such occurrences were particularly evident in the Ciskei, which largely emerged as a receptacle for countless relocated African families, and whose land and amenities was controlled, and then dispensed through state-created tribal authorities. Those contrived power brokers served at the base of government hierarchy but were equally influential in linking services to loyalists of the Bantustan system whilst fostering its social and political patronage networks. Naturally, the system impelled reaction and contestation in the form of robust civic movements from those the Bantustan policy sought to incorporate by early 1980s. Equally, such civic movements widened by the late 1980s to include even those already within the Ciskei Bantustan, but initially alienated from land and services allotted by tribal authorities. By then this movement had become key to rural and urban representative voices and was no longer restricted to the Ciskei. It marked a Border-Kei region of the current Eastern Cape Province, which from the early 1990s coalesced around the Ciskei, the western parts of the Transkei and the enfolded former white farming districts with their towns. How then did the calibrated local authority system after 1994 typify various formations of this area against persistent land demands and services, as well as reorganising chiefly authorities (now referred to as traditional authority)? To what extent did governance and distribution of services continue being routed for benefaction? This paper provides an historical outline of the campaign for egalitarian local authority, and ultimately shows the early complexities of an integrated municipality in 2000 in that hitherto segregated Border-Kei region of South Africa’s Eastern Cape.
Perceptions of death and memory transmission among residents of Hiroshima and Nagasaki, Japan: A qualitative study
Authors: Richardson Monte-Angel , Parmer Carly
Published: August 2023

The understanding and materialization of grief and loss in a community are contingent upon cultural norms, historical processes, and dominant political narratives. The processes of public mourning create a localized memory of the deceased which contributes to a collective narrative formation around loss. When death is made public, politicized, or collectively grieved, there exists great momentum for enacting policy change through restorative justice practices. This momentum for resistance is amplified when collective grieving takes place following political or mass deaths. The present study aims to develop a holistic understanding of mourning and memorialization practices as they are locally enacted in Hiroshima and Nagasaki, Japan. These two cities were chosen based on their shared history of mass violence and their diverging cultural customs of mourning. Twelve qualitative interviews were conducted with residents of both cities. The purpose of the interviews was to gain insight to how Hiroshima and Nagasaki residents make meaning out of loss and public memorialization. Narrative interviews based on the Miyabayashi Grief Measurement (MG) allowed participants to explain and reflect on the links between their public and individual mourning practices. Themes identified in the interviews include (1) a routine and automatic engagement with grief rituals specific to Japanese culture; (2) connection and gratitude towards ancestors; (3) methods of engaging with memorial sites to transmit personal memories of the deceased; (4) a sense of duty in passing on the first-hand accounts of survivors of the atomic bombing; (5) recalling memories of the deceased when making decisions; and, (6) transmitting memories of loss in a way that is celebratory and joyous. These results ask us to look past simplified depictions of cultural grief and consider the individual elements that may impact a person’s remembrance and memory transmission within societies.
Mortality after emergency unit fluid bolus in febrile Ugandan children
Authors: Rice Brian , Hawkins Jessica , Nakato Serena , Kamara Nicholas ,   on behalf of Global Emergency Care Investigator Group
Published: August 2023

Objectives

Pediatric fluid resuscitation in sub-Saharan Africa has traditionally occurred in inpatients. The landmark Fluid Expansion as Supportive Therapy (FEAST) trial showed fluid boluses for febrile children in this inpatient setting increased mortality. As emergency care expands in sub-Saharan Africa, fluid resuscitation increasingly occurs in the emergency unit. The objective of this study was to determine the mortality impact of emergency unit fluid resuscitation on febrile pediatric patients in Uganda.

Methods

This retrospective cohort study used data from 2012–2019 from a single emergency unit in rural Western Uganda to compare three-day mortality for febrile patients that did and did not receive fluids in the emergency unit. Propensity score matching was used to create matched cohorts. Crude and multivariable logistic regression analysis (using both complete case analysis and multiple imputation) were performed on matched and unmatched cohorts. Sensitivity analysis was done separately for patients meeting FEAST inclusion and exclusion criteria.

Results

The analysis included 3087 febrile patients aged 2 months to 12 years with 1,526 patients receiving fluids and 1,561 not receiving fluids. The matched cohorts each had 1,180 patients. Overall mortality was 4.0%. No significant mortality benefit or harm was shown in the crude unmatched (Odds Ratio [95% Confidence Interval] = 0.88 [0.61–1.26] or crude matched (1.00 [0.66–1.50]) cohorts. Adjusted cohort analysis (including both complete case analysis and multiple imputation) and sensitivity analysis of patients meeting FEAST inclusion and exclusion criteria all also failed to show benefit or harm. Post-hoc power calculations showed the study was powered to detect the absolute harm seen in FEAST but not the relative risk increase.

Conclusions

This study’s primary finding is that fluid resuscitation in the emergency unit did not significantly increase or decrease three-day mortality for febrile children in Uganda. Universally aggressive or fluid-sparing emergency unit protocols are unlikely to be best practices, and choices about fluid resuscitation should be individualized.