bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from Paclitaxel-Dependent Cell Lines Reveal a Novel Drug Activity
Authors: Ganguly Anutosh , Yang Hailing , Cabral Fernando
Published: April 2023

Supplementary Figure 1 from Paclitaxel-Dependent Cell Lines Reveal a Novel Drug Activity
Supplementary Figure 2 from miR-192/miR-215 Influence 5-Fluorouracil Resistance through Cell Cycle-Mediated Mechanisms Complementary to Its Post-transcriptional Thymidilate Synthase Regulation
Authors: Boni Valentina , Bitarte Nerea , Cristobal Ion , Zarate Ruth , Rodriguez Javier , Maiello Evaristo , Garcia-Foncillas Jesus , Bandres Eva
Published: April 2023

Supplementary Figure 2 from miR-192/miR-215 Influence 5-Fluorouracil Resistance through Cell Cycle-Mediated Mechanisms Complementary to Its Post-transcriptional Thymidilate Synthase Regulation
Supplementary Figure 4 from Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition
Authors: Breuleux Madlaina , Klopfenstein Matthieu , Stephan Christine , Doughty Cheryl A. , Barys Louise , Maira Saveur-Michel , Kwiatkowski David , Lane Heidi A.
Published: April 2023

Supplementary Figure 4 from Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition
Supplementary Figure 3 from Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis
Authors: Chen Ying , Hao Hua , He Songqing , Cai Lei , Li Yongsheng , Hu Shunze , Ye Duyun , Hoidal John , Wu Ping , Chen Xiaoping
Published: April 2023

Supplementary Figure 3 from Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis
Supplementary Table from AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
Authors: Zabludoff Sonya D. , Deng Chun , Grondine Michael R. , Sheehy Adam M. , Ashwell Susan , Caleb Benjamin L. , Green Stephen , Haye Heather R. , Horn Candice L. , Janetka James W. , Liu Dongfang , Mouchet Elizabeth , Ready Shannon , Rosenthal Judith L. , Queva Christophe , Schwartz Gary K. , Taylor Karen J. , Tse Archie N. , Walker Graeme E. , White Anne M.
Published: April 2023

Supplementary Table from AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
Supplementary Fig. S2 from Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells
Authors: Weisberg Ellen , Wright Renee D. , McMillin Douglas W. , Mitsiades Constantine , Ray Arghya , Barrett Rosemary , Adamia Sophia , Stone Richard , Galinsky Ilene , Kung Andrew L. , Griffin James D.
Published: April 2023

Supplementary Fig. S2 from Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells
Supplementary Fig. S1 from Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells
Authors: Weisberg Ellen , Wright Renee D. , McMillin Douglas W. , Mitsiades Constantine , Ray Arghya , Barrett Rosemary , Adamia Sophia , Stone Richard , Galinsky Ilene , Kung Andrew L. , Griffin James D.
Published: April 2023

Supplementary Fig. S1 from Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells
Supplementary Fig. S6 from Dual silencing of insulin-like growth factor-I receptor and epidermal growth factor receptor in colorectal cancer cells is associated with decreased proliferation and enhanced apoptosis
Authors: Kaulfuβ Silke , Burfeind Peter , Gaedcke Jochen , Scharf Jens-Gerd
Published: April 2023

Supplementary Fig. S6 from Dual silencing of insulin-like growth factor-I receptor and epidermal growth factor receptor in colorectal cancer cells is associated with decreased proliferation and enhanced apoptosis
Supplementary Fig. S1 from Dual silencing of insulin-like growth factor-I receptor and epidermal growth factor receptor in colorectal cancer cells is associated with decreased proliferation and enhanced apoptosis
Authors: Kaulfuβ Silke , Burfeind Peter , Gaedcke Jochen , Scharf Jens-Gerd
Published: April 2023

Supplementary Fig. S1 from Dual silencing of insulin-like growth factor-I receptor and epidermal growth factor receptor in colorectal cancer cells is associated with decreased proliferation and enhanced apoptosis
Supplementary Figure 5 from Identification of LIV1, a Putative Zinc Transporter Gene Responsible for HDACi-Induced Apoptosis, Using a Functional Gene Screen Approach
Authors: Ma Xiaoli , Ma Quanfu , Liu Jia , Tian Yuan , Wang Beibei , Taylor Kathryn M. , Wu Peng , Wang Daowen , Xu Gang , Meng Li , Wang Shixuan , Ma Ding , Zhou Jianfeng
Published: April 2023

Supplementary Figure 5 from Identification of LIV1, a Putative Zinc Transporter Gene Responsible for HDACi-Induced Apoptosis, Using a Functional Gene Screen Approach
Supplementary Table S2 from Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters
Authors: Okabe Mitsunori , Szakács Gergely , Reimers Mark A. , Suzuki Toshihiro , Hall Matthew D. , Abe Takaaki , Weinstein John N. , Gottesman Michael M.
Published: April 2023

Supplementary Table S2 from Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters
Supplementary Data from The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors
Authors: Jain Lokesh , Vargo Craig A. , Danesi Romano , Sissung Tristan M. , Price Douglas K. , Venzon David , Venitz Jürgen , Figg William D.
Published: April 2023

Supplementary Data from The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors
Supplementary Table 1 from Reprogramming Murine Telomerase Rapidly Inhibits the Growth of Mouse Cancer Cells In vitro and In vivo
Authors: Xu Tong , Xu Yucheng , Liao Chun-Peng , Lau Roy , Goldkorn Amir
Published: April 2023

Supplementary Table 1 from Reprogramming Murine Telomerase Rapidly Inhibits the Growth of Mouse Cancer Cells In vitro and In vivo
Adobe PDF - MCT-06-0552--Suppl_Table_S1.pdf from Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial
Authors: Thomas Huw D. , Calabrese Christopher R. , Batey Michael A. , Canan Stacie , Hostomsky Zdenek , Kyle Suzanne , Maegley Karen A. , Newell David R. , Skalitzky Donald , Wang Lan-Zhen , Webber Stephen E. , Curtin Nicola J.
Published: April 2023

Adobe PDF - MCT-06-0552--Suppl_Table_S1.pdf from Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial
Supplementary Material from A two-tiered physiologically based model for dually labeled single-chain Fv-Fc antibody fragments
Authors: Ferl Gregory Z. , Kenanova Vania , Wu Anna M. , DiStefano Joseph J.
Published: April 2023

Supplementary Material from A two-tiered physiologically based model for dually labeled single-chain Fv-Fc antibody fragments
Design and fabrication of an IoT-based smart electrical meter for residential energy management
Authors: Ba Nguyen Thanh , Cao Nguyen Tri
Published: April 2023

Transparency in electricity measurement and efficient use of electricity are issues of concern to households. Electricity customers want to have confidence in their utility company's electricity meters installed at their houses. This study designs and constructs an internet of things (IoT)-based smart electric meter to measure electricity and remotely control domestic appliances. This device can monitor, calculate electricity bills and remotely control the appliances via the internet; electrical quantities are displayed in real-time on the Blynk app, liquid crystal display (LCD) screen and Google Sheet. The device is also capable of emailing the electricity user. The proposed system is designed and developed based on ESP32, a LCD, a PZEM 004T, four relays and a DC source. The results show that the device works stably and the device’s error is less than 5%. This research makes it possible for users to conveniently monitor their power consumption while enhancing their energy-saving awareness.
Stability analysis of smart grid management system on campus building
Authors: Maizana Dina , Rezky Ahmad , Muthia Putri Syarifah , Satria Habib , Mungkin Moranain
Published: April 2023

Medan Area University is one of the private universities in North Sumatra that is also involved in the development of renewable energy technology. This technological development has initiated the University's efforts to develop an electrical system by developing a smart grid system in order to reduce the University's operational costs. However, in its realization, it has its own challenges, such as power flow stability and transient stability. Both problems can be analyzed using ETAP 12.6 software. In one of the cases analyzed, the smart grid system can reduce the use of the active power of the transformer by 11 kW and a current of 19.7 Amp. Meanwhile, in the Indonesian State Electricity Company (PLN) off condition, the smart grid system has not been able to supply the load because the availability of renewable energy sources is not sufficient for the load requirement. As well as the results of the voltage and frequency analysis, the highest voltage is 376.4 Volts, the lowest is 375.9 Volts, which is still in the stable category of 380 Volt voltage deviation because it is not +5% and -10%, and the overall frequency of the cases discussed is consistent stable at nominal 50 Hz.
Speed control of brushless DCmotors using (conventional, heuristic, and intelligent) methods-based PID controllers
Authors: Kammel Shary Diyah , Jaber Nekad Habeeb , Abdulelah Alawan Mazin
Published: April 2023

One of the most often utilized types of direct current (DC) motors in both the industrial and automotive sectors are brushless DC motors (BLDC). This research presents a comparative analysis on brushless DC motor speed management. A mathematical model of the BLDC motor is developed using MATLAB/Simulink, and its speed is tested using three alternative controller types. The first controller is a traditional proportional integral derivative (PID) controller for BLDC motor speed control. The second controller used the particle swarm optimization (PSO) approach with PID which give the best response for BLDC motor speed. The PID controller in the third method based on neural network also give best reaction on motor speed. Finally, comparison made in speed and torque profiles by using sudden changes in speed and load torque under the three proposed methods. The results show when using first controller the speed rise to 1,526 r.p.m and drop to 1,400 r.p.m at the test conditions. These oscillations will disappear when using the second and third controller.
A review of solar drying technology for agricultural produce
Authors: Rizalman Mohd Khairulanwar , Moung Ervin Gubin , Dargham Jamal Ahmad , Jamain Zuhair , Yaakub Nurul’azah Mohd , Farzamnia Ali
Published: April 2023

Agriculture contributes to large export earnings for many countries and provides food all over the world. However, most agricultural products need some post-harvest processing, such as drying, to extend their shelf life while still maintaining their respective nutrient quality. One popular post-harvest processing method is drying using solar energy. It is a type of renewable energy that is abundant and free. Conventional dryers use grid electricity and can be expensive to operate. Consequently, there is a growing need for cost-effective solar-powered agricultural dryers that is reasonable for smaller-scale farmers. Although current solar dryers are still not on par with modern electricity-powered dryers, solar dryers have lower running costs and are sustainable and able to generate electricity. They can also be used practically anywhere with abundant solar energy. As numerous solar drying technologies have been proposed over the past decade, it is necessary to assess the current state of solar drying technology in the agricultural sector to identify current advancements and potential research gaps. In this paper, a review of existing solar dryers mechanism and the state of the art of solar drying technology research for agricultural products is presented.
Optimal sliding mode controller for lower limb rehabilitation exoskeleton in constrained environments
Authors: A. Faraj Mohammad , Maalej Boutheina , Derbel Nabil
Published: April 2023

In this article, a lower limb exoskeleton (LLE) under contacting constrained motion has been modelled using augmented Lagrange equations which include Lagrange multiplier and Jacobian vectors. A sliding mode Controller optimized by the grey Wolf optimization algorithm has been used for controlling (LLE) in the case of constrained motion with uncertainties and outside perturbation. The grey wolf optimization algorithm has been used as an optimization algorithm for finding the optimal controllers’ parameters in order to improve the performance of the system. The stability analysis of the closed-loop system has been performed using Lyapunov theory of stability. To validate the effectiveness of the proposed controller structure grey wolf optimization algorithm controller (GW-SMC), a series of comparative simulations have been carried out with other types of recently existing sliding mode control (SMC). The results of numerical simulations indicate the superiority of the sliding mode optimized by the GW-SMC over other types of recently existing controller in terms of tracking errors and robustness towards uncertainties and external disturbances.
Sustainable framework for a geostationary satellite control earth station system using parallel configuration
Authors: Rahman Nur Shazana Abdul , Rahim Nadirah Abdul
Published: April 2023

Earth station system plays an important role to ensure that a satellite communication system runs efficiently. Redundancies of the subsystems and regular maintenance planning can improve the earth station system. Organising system affordability can be challenging as more redundancies would acquire more maintenance. Thus, a sustainable framework that considers an earth station system's reliability, cost, and maintainability was modelled. 2-parallel, 3-parallel, and 4-parallel earth station system configurations were studied with five mean time between failures (MTBF). The results showed that an earth station that was configured with 2-parallel configuration provided an optimum reliability system performance though both 3-parallel and 4-parallel configuration provided higher reliability. Moreover, the 2-parallel configuration was also cheaper in terms of operational cost if compared to the 3-parallel and the 4-parallel configurations. Hence, this sustainable framework comprising the reliability and operational cost elements were modelled based on the 2-parallel configuration with the proposed maintenance activities. Moreover, the computed root mean square (RMS) values for both new reliability and new operational cost models yielded smallest values of 20.84% and 22.82% respectively. Thus, these RMS values for both reliability and operational cost models based on 2-parallel configuration are suitable to be applied in the earth station system design.
Efficient reconfigurable architecture to enhance medical image security
Authors: Marakumbi Prakash , Bhairannawar Satish
Published: April 2023

Medical images are one of the most critical and sensitive types of data in information systems. For the secure storage and transfer of medical images, confidentiality is the most important aspect. This paper presents efficient embedding technique to enhance medical image security. The Gaussian filters are used as preprocessing to remove high frequency components and then applied to cumulative distribution function (CDF) 5/3 wavelet to obtain LL band features. Similarly, the LL band features of cover image are obtained. The alpha bending technique combines both the LL band features of cover and secret image to form first level of encryption and now with other high frequency bands of LH, HL and HH applied to Inverse CDF 5/3 obtains an encrypted image which is then transferred along with key obtained through other bands of LH, HL and HH. The key generated acts as additional level of security and similarly, at the receiver the opposite operations are performed to obtain the original secrete image. The performance is measured in terms of Peak signal-to-noise ratio (PSNR) and is compared with existing techniques to validate the results. Further, the entire architecture is synthesized on spartan 6 field-programmable gate array (FPGA) board to compare the hardware utilizations.
A new method based on swarm intelligence with encrypted data in wireless sensor networks
Authors: Altmemi Dhuha Kh. , Yaseen Basim Sahar
Published: April 2023

Wireless sensor networks (WSNs) technology is one of the most essential Internet of things technologies. It is utilized efficiently in a variety of real-world applications, including healthcare, environmental monitoring, tracking, etc. WSNs are composed of sensor nodes with restricted resources. However, the communication between WSN components is not secure. Therefore, it is necessary to build efficient and lightweight cryptographic algorithms to secure shared data. Our paper comprises proposes a secure protocol called grasshopper optimization algorithm routing protocol (GOARP) with a lightweight encryption method in each sensor called rivest cipher 5 (RC5) to enhance network efficiency and simulation in terms of power consumption, required memory space, and computational time. Subsequently, the network lifetime result achieved in the proposed method is about (70%) more than in GOA elliptic curve cryptographic and Diffie Hellman (GOA-ECCDH).
University of Kufa unified laboratories management system using computer application
Authors: Hadi Faris Sattar , Farawn Ali Al , Alhilali Ahmed Hazim
Published: April 2023

The laboratory organization is essential in the university to maximize system convenience, accuracy, appropriateness, and sustainability. The laboratory data system is an information supplier that aids in arranging data sources and decision-making processes. In this work, unified laboratories management system (ULMS) was presented in the educational field for managing and scheduling lab equipment information. There are two steps in the research process: the first is to examine the old approach for organizing and scheduling laboratory equipment and suggest a better one. The approach adopted in this system is the first come, first served rule governs task priority (FCFS). The second step is creating a computerized system for scheduling and managing laboratory equipment. For programming, C# and structured query language (SQL) are used. This system's design included user and administrative integration (manager, technicians, and researchers). An information application system plan was created because of this research to manage the scheduling information for lab equipment. As a result, it can help the management of the laboratory describe all operational tasks in a way that is considerably simpler and produces outcomes more quickly and accurately.
An intelligent road accident reduction system using device-to-device communication
Authors: Jabid Taskeed , Rizvy Nazmul Hasan , Mow Fateza Tuj Zohora , Shosy Tanjina Zaman , Ali Md. Sawkat , Islam Maheen , Hassan Samia Binta , Hasan Mahamudul
Published: April 2023

Every year thousands of people are dying due to road accidents and most of the accidents are occurring in urban areas and highways. As the number of vehicles is increasing day by day, the probability of the occurrence of the accident is also increasing. A system has been introduced in this paper that can reduce road accidents by sending an alert to drivers via smartphones. For this purpose, an android-based application has been developed. To reduce the accident, every driver of the car must have the application. Firstly, the location of the vehicle will be collected from the driver’s smartphone, then the data will be sent to the server through the application. An algorithm has been also developed using Haversine Formula which calculates the distance among the vehicles. A total of five cases have been implemented according to the dataset and compared for the performance evaluation. An extensive experimental study and comparison have been performed with the other methods where a complete performance is focused that can be claimed to reduce road accidents via the device-to-device communication process.
Effective resource virtualization for dynamic IoT devices in road network
Authors: P. Padmanabhan , K. Sampath Kumar , A. John
Published: April 2023

Internet of things (IoT), which is considerably innovating and generating a large volume of processes in every field worldwide, is one of the recent and next disruptive technologies. As a result, IoT devices and others are increasing network connections in the relevant field. It is essential to maximize and process these kinds of resources. The effective usage of resources is one of the most important and very difficult to manage the resource in the dynamic environments. Many studies are performed in the effective usage of resource in the static and dynamic environments. However, the dynamic environments have still different issues and have to solve different dynamic networking issues. In this work, present a mechanism for managing different connecting devices in the dynamic environments. Especially this system is concentrating on road network device management in dynamic environments. The proposed system called dynamic road sensing (DyRSen) connectivity is support to different continuous connectivity. The DyRSen provides: i) continuous connectivity using available resources and provide virtual environment for computing, ii) temporary data storage in dynamic environment for effective resource sharing, and iii) reduce the energy utilization and network overhead and the effective resource management is compared to the other works.
Collaborative desing in web aplication development to improve tuberculosis diagnostic
Authors: Juan Freyre Medrano , Carolina Calixto Palacios , Patricia Condori Obregon , Carlos Palomino Vidal
Published: April 2023

In Peruvian Tuberculosis Reference Laboratory of the Regional Health Directorate of Callao, issues related to the diagnostic process where identified, because of the slowly generations of patients result. This research develops a web application to solve these issues using a participatory design. Qualitative data were recollected through interviews and focus groups in 45 medical centers belong to the regional health directorate (DIRESA) from Callao. These data were used to define the correct design and develop the required processes in the web application. Quantitative data were recollected either, to measure the efficiency of the new diagnostic process using the web application. The results show that with the use of the web application 120 hours were reduce from the monthly validation results and avoid the generation of 8,700 duplicate information, with these results the diagnostic process was improve. The research also confirms that the design and use of technological tools in a collaborative environment improve the process efficiency.
Facial recognition for partially occluded faces
Authors: Naser Omer Abdulhaleem , Ahmad Sharifah Mumtazah Syed , Samsudin Khairulmizam , Hanafi Marsyita , Shafie Siti Mariam Binti , Zarina Nor Zamri
Published: April 2023

Facial recognition is a highly developed method of determining a person's identity just by looking at an image of their face, and it has been used in a wide range of contexts. However, facial recognition models of previous researchers typically have trouble identifying faces behind masks, glasses, or other obstructions. Therefore, this paper aims to efficiently recognise faces obscured with masks and glasses. This research therefore proposes a method to solve the issue of partially obscured faces in facial recognition. The collected datasets for this study include CelebA, MFR2, WiderFace, LFW, and MegaFace Challenge datasets; all of these contain photos of occluded faces. This paper analyses masked facial images using multi-task cascaded convolutional neural networks (MTCNN). FaceNet adds more embeddings and verifications to face recognition. Support vector classification (SVC) labels the datasets to produce a reliable prediction probability. This study achieved around 99.50% accuracy for the training set and 95% for the testing set. This model recognizes partially obscured digital camera faces using the same datasets. We compare our results to comparable dataset studies to show how our method is more effective and accurate.
Modeling and automatic generation of data warehouse using model-driven transformation in business intelligence process
Authors: Esbai Redouane , Hakkou Soufiane , Habri Mohamed Achraf
Published: April 2023

The work presented in this paper focuses on the modeling and implementation of business intelligence processes, specifically how to apply model-driven architecture (MDA) throughout the entire development process of a data warehouse to automatically generate the multidimensional schema. As a result, this work specifies different rules for automating the process of obtaining an online analytical processing (OLAP) cube and implementing it using a collection of metamodels and automatic transformations. The data warehouse relational and OLAP cube models are then created using a model transformation from the conceptual model (class diagram). Finally, the XML file and SQL code are generated for creating the OLAP cubes and relational data warehouse, respectively. Using transformation languages like query-view-transformation (QVT) and Acceleo, all model transformations are performed.
Zebrafish ELL-associated factors Eaf1/2 modulate erythropoiesis via regulating gata1a expression and WNT signaling to facilitate hypoxia tolerance
Authors: Liu WenYe , Lin ShuHui , Li LingYa , Tai ZhiPeng , Liu Jing-Xia
Published: April 2023

EAF1 and EAF2, the eleven-nineteen lysine-rich leukemia (ELL)-associated factors which can assemble to the super elongation complex (AFF1/4, AF9/ENL, ELL, and P-TEFb), are reported to participate in RNA polymerase II to actively regulate a variety of biological processes, including leukemia and embryogenesis, but whether and how EAF1/2 function in hematopoietic system related hypoxia tolerance during embryogenesis remains unclear. Here, we unveiled that deletion of EAF1/2 (eaf1−/− and eaf2−/−) caused reduction in hypoxia tolerance in zebrafish, leading to reduced erythropoiesis during hematopoietic processes. Meanwhile, eaf1−/− and eaf2−/− mutants showed significant reduction in the expression of key transcriptional regulators scl, lmo2, and gata1a in erythropoiesis at both 24 h post fertilization (hpf) and 72 hpf, with gata1a downregulated while scl and lmo2 upregulated at 14 hpf. Mechanistically, eaf1−/− and eaf2−/− mutants exhibited significant changes in the expression of epigenetic modified histones, with a significant increase in the binding enrichment of modified histone H3K27me3 in gata1a promoter rather than scl and lmo2 promoters. Additionally, eaf1−/− and eaf2−/− mutants exhibited a dynamic expression of canonical WNT/β-catenin signaling during erythropoiesis, with significant reduction in p-β-Catenin level and in the binding enrichment of both scl and lmo2 promoters with the WNT transcriptional factor TCF4 at 24 hpf. These findings demonstrate an important role of Eaf1/2 in erythropoiesis in zebrafish and may have shed some light on regeneration medicine for anemia and related diseases and on molecular basis for fish economic or productive traits, such as growth, disease resistance, hypoxia tolerance, and so on.
EVALUATION OF THE INFLUENCE OF THE USE OF BIOLOGICAL PREPARATIONS DURING THE VEGETATION PERIOD ON THE MICROBIOME OF SPRING WHEAT SEEDS
Authors: Diabankana Roderik Zhil' Klare , Safin Radik
Published: April 2023

An assessment is made of the effect of spraying plants with biological products on the total microbiome of seeds of a new crop. The studies were carried out on three varieties of spring wheat of domestic breeding - Yoldyz, Burlak and Ulyanovsk-105. Preparations based on strains of endophytic bacteria isolated from seeds of spring wheat (Bacillus mojavensis PS17, Bacillus velezensis KS25) and spring barley (Bacillus velezensis KS31, Bacillus subtilis KS38) were used as biological preparations. The treatment of spring wheat crops was carried out in the phase of entry into the tube using the biological product consumption rate of 1.0 l/ha. The impact of treatments on the fungal and bacterial microbiome was assessed using quantitative PCR methods with the determination of the total (total) DNA of microorganisms per unit weight of seeds. In most cases, the use of treatment with endophytic bacteria reduces the amount of total micromycete DNA on seeds. Among the studied isolates, the Bacillus subtilis KS-38 strain was especially distinguished, which provided a significant (7.7-11.1 times) decrease in this indicator in all varieties. Bacillus mojavensis PS-17 had a significant effect (a decrease of almost 47 times) on the Ulyanovska 105 variety, and Bacillus velezensis KS-31 on the Burlak variety. On varieties Yoldyz and Ulyanovska 105, the most significant decrease in the total DNA of micromycetes was noted for endophytes obtained from spring wheat seeds (Bacillus mojavensis PS-17, Bacillus velezensis KS-25), and on variety Burlak, endophytes from spring barley seeds (Bacillus velezensis KS-31 and Bacillus subtilis KS-38). The decrease in the total DNA of micromycetes in the experiments was due to the use of the studied biological products and, to a lesser extent, varietal characteristics. For the bacterial microbiome, there were strong differences between varieties. A significant increase in the total DNA of bacteria in all studied varieties was in Bacillus mojavensis PS-17 and Bacillus velezensis KS-31. The variety (29.9%) made the greatest contribution to the variability in the content of total bacterial DNA in seeds, and the contribution of biological preparations was lower (25.5%). In the experiments, no correlation was found between the indicators of the total DNA of micromycetes and bacteria in spring wheat seeds.
INCREASE IN THE YIELD OF PLANTING MATERIAL WHEN USING THE METHOD OF LIGNIFIED CUTTINGS OF GRAPES
Authors: Abramov Aleksandr , Abramova Galina , Ismail Shaimaa Helmi , Shalamova Anna
Published: April 2023

When growing high-quality grape seedlings, an effective organization of production is required, aimed at the intensification and development of the industry. Rooting grapes with lignified cuttings is one of the most effective and economical methods of reproduction. The article presents the results of three-year studies (2019-2021) to study the effect of biologically active substances on the rootability of lignified grape cuttings. The object of the study is the Victoria grape variety obtained by crossing Vitis amurensis and Vitis vinifera with the Save Vilar 12-304 variety in VNIIVIV im. Yakov Ivanovich Potapenko. The variety under study is a table variety with an early ripening period, characterized by increased resistance to powdery mildew, oidium and gray rot. Withstands low negative temperatures up to -26 ... - 27ºC, with a period from budding to removable ripeness of 115-120 days. During the experiment, records were made about the growth of callus, rooting and output of standard seedlings. When studying the effect of biologically active substances on lignified cuttings, they were treated with salicylic and β-indolyl butyric acids at concentrations of 2000 and 3000 mg/l. As a result of the conducted studies, it was found that the highest percentage of rooting was obtained in the variant using salicylic acid at a concentration of 2000 mg/l and reached 84.5% on average over three years. The same version of the experiment showed the maximum yield of standard seedlings - up to 76.3% on average for three years.
High energy solutions of general Kirchhoff type equations without the Ambrosetti-Rabinowitz type condition
Authors: Zhang Jian , Liu Huize , Zuo Jiabin
Published: April 2023

In this article, we study the following general Kirchhoff type equation:

−
M

∫

R

3

∣

∇

u

∣

2

d
x

Δ
u
+
u
=
a

(

x

)

f

(

u

)

in

R

3

,

-M\left(\mathop{\int }\limits_{{{\mathbb{R}}}^{3}}| \nabla u{| }^{2}{\rm{d}}x\right)\Delta u+u=a\left(x)f\left(u)\hspace{1em}{\rm{in}}\hspace{0.33em}{{\mathbb{R}}}^{3},

where

inf

R

+

M
>
0

{\inf }_{{{\mathbb{R}}}^{+}}M\gt 0

and

f

f

is a superlinear subcritical term. By using the Pohozǎev manifold, we obtain the existence of high energy solutions of the aforementioned equation without the well-known Ambrosetti-Rabinowitz type condition.
Transient particle tracking microrheology of plasma coagulation via the intrinsic pathway
Authors: Mao Yating , Tan Mingyang , Kohs Tia C. L. , Sylman Joanna L. , Ngo Anh T. P. , Puy Cristina , McCarty Owen J. T. , Walker Travis W.
Published: April 2023

The maintenance of hemostasis to ensure vascular integrity is dependent upon the rapid conversion of zymogen species of the coagulation cascade to their enzymatically active forms. This process culminates in the generation of the serine protease thrombin and polymerization of fibrin to prevent vascular leak at sites of endothelial cell injury or loss of cellular junctions. Thrombin generation can be initiated by the extrinsic pathway of coagulation through exposure of blood to tissue factor at sites of vascular damage, or alternatively by the coagulation factor (F) XII activated by foreign surfaces with negative charges, such as glass, through the contact activation pathway. Here, we used transient particle tracking microrheology to investigate the mechanical properties of fibrin in response to thrombin generation downstream of both coagulation pathways. We found that the structural heterogeneity of fibrin formation was dependent on the reaction kinetics of thrombin generation. Pharmacological inhibition of FXII activity prolonged the time to form fibrin and increased the degree of heterogeneity of fibrin, resulting in fibrin clots with reduced mechanical properties. Taken together, this study demonstrates a dependency of the physical biology of fibrin formation on activation of the contact pathway of coagulation.
The associative system of early-learned Hebrew verbs and body parts: a comparative study with American English
Authors: Maouene Josita , Sethuraman Nitya , Uziel-Karl Sigal , Hidaka Shohei
Published: April 2023

This paper compares the associative system of early-learned verbs and body parts in Hebrew with previously published data on American English (Maouene, Josita, Shohei Hidaka & Linda B. Smith. 2008. Body parts and early-learned verbs. Cognitive Science 32(7). 1200–1216). Following the methodology of the former study, 51 Hebrew-speaking college students gave the first body part that came to mind for each of 103 early-learned Hebrew verbs, 81 of which were translational equivalents. Rate of convergence and divergence and underlying patterns were used to make inferences about the constraints at work. Overall convergence (92.3% of the Hebrew data and 93.7% of the English data) reveal similar entropy levels, comparable semantic field shapes of verbs organized by body parts and similar general cluster patterns of verbs by body parts. Most divergence lies in the infrequent responses (offered fewer than 1% of the time) which arise around body parts that are internal, very detailed, very general categorically, used in figurative language, uniquely provided and tend to be subject to cultural taboos. This is a new contribution, as previous work has not quantified the relative proportion of convergent to divergent associations. We discuss how these findings support neural and developmental continuity and stability in the verbal system with respect to the categorization of verbs by body parts cross-culturally.
Power flow control and power oscillation damping in a 2-machine system using SSSC during faults
Authors: Sharma Kartikey , Nimje Akhilesh A. , Godwal Shanker D.
Published: April 2023

With the rapidly growing population, energy demand is increasing. The power supply to consumers must be free from distortions. By injecting voltage in quadrature with line current and varying the magnitude, the SSSC offers series compensation to the line. The injected voltage, which offers the effect of inserting an inductive or else capacitive reactance in series with the transmission line, is in quadrature with the line current. Using MATLAB/Simulink software, a phasor model of a 2-machine device with SSSC integration and POD as a subsidiary controller is simulated in this paper to evaluate efficient power flow regulation. The simulation has been used to study the time domain behavior of SSSC under normal and faulty conditions. The SSSC is implemented for correcting the voltage and analyzing power responses during a low voltage fault in the power system, whereas in normal conditions, the power system’s voltage stability for maintaining steady acceptable voltages at every bus is analyzed. It has been revealed that POD controller assists SSSC by supplying the reference voltage signal to damp out the low frequency power oscillations. The objective of this study is to reduce the crest outreach and clearing time during the fault thus improving the transient stability.
Can You Have Your Corporate Wokeism and Eat it too?
Authors: Weisman Dennis L.
Published: April 2023

Corporate wokeism may be sustainable in an imperfectly competitive market when the higher costs driven by the inefficiency in employing labor inputs are offset by the increase in positive-margin sales generated from being “woke.” This is the mechanism by which woke corporations are potentially rewarded rather than punished by the competitive process in the new market economy.
New semi-empirical systematic of (p,n) reaction cross section at 7.5 MeV
Authors: Lyes Omeir , Amrani Naima
Published: April 2023

It is advised to use a new formula to calculate the (p, n) reaction cross section at 7.5 MeV. We propose six new parameters for the formula proposed by Broeders, C. and Konobeyev, A.Y. (2008. Systematics of (p,n) reaction crosssection. Radiochim. Acta 96: 387–397) to fit experimental data. It should be noted that our systematics is only applicable to isotopes with a ratio of 7.5 MeV to the reaction threshold above 1.3 (7.5/E

th
 > 1.3). This is based on analytical calculations generated from the semi-empirical mass formula, the evaporation model, and the pre-equilibrium exciton model. We were able to find new parameters for the Broders et al. formula through this inquiry that guarantee a good fit with the revised experimental data (EXFOR2022) and provide a minimum value for the statistical parameters ∑ and χ
2.
Well-posedness for bilevel vector equilibrium problems with variable domination structures
Authors: Xu Yu-ping , Wang San-hua , Li Qiu-ying , Lu Bing-yi
Published: April 2023

In this article, well-posedness for two types of bilevel vector equilibrium problems with variable domination structures are introduced and studied. With the help of cosmically upper continuity or Hausdorff upper semi-continuity for variable domination structures, sufficient and necessary conditions are given for such problems to be Levitin-Polyak (LP) well-posed and LP well-posedness in the generalized sense. As variable domination structure is a valid generalization of fixed one, the main results obtained in this article extend and develop some recent works in the literature.
IRF6andFGF1polymorphisms in non-syndromic cleft lip with or without cleft palate in the Polish population
Authors: Zawiślak Alicja , Woźniak Krzysztof , Kawala Beata , Gupta Satish , Znamirowska-Bajowska Anna , Janiszewska-Olszowska Joanna , Lubiński Jan , Calvo-Guirado José Luis , Grocholewicz Katarzyna , Jakubowska Anna
Published: April 2023

Non-syndromic cleft lip with or without cleft palate (NSCL/P) is the most common developmental defect that significantly affects the morphology and function of the stomatognathic system in children. The etiology of these birth defects is multifactorial, and single nucleotide polymorphisms (SNPs) inIRF6andFGF1have been associated with NSCL/P. This study aimed to evaluate whether SNPs inIRF6, namely rs2013162, rs642961, rs2235373, and rs34010 inFGF1, are associated with NSCL/P occurrence in the Polish population. The study included 627 participants: 209 children with NSCL/P and 418 healthy controls. DNA was isolated from saliva in the study group and from umbilical cord blood in controls. Genotyping of polymorphisms was performed using quantitative PCR. There was no statistically significant association ofIRF6gene variants with NSCL/P occurrence, although for rs2013162, AA genotype, odds ratio (OR) = 1.16 and for AC genotype, OR = 0.83; for rs642961, AA genotype, OR = 0.84 and for AG genotype, OR = 1.41; and for rs2235373, AA genotype, OR = 0.79 and for AG, OR = 0.85. In the instance of rs34010 polymorphism inFGF1, the presence of the AA genotype was statistically significant in reducing the risk of NSCL/P (OR = 0.31,p= 0.001). Genetic variation inFGF1is an important risk marker of NSCL/P in the Polish population, which cannot be stated for the polymorphisms in theIRF6gene.
Topological Properties of Jordan Intuitionistic Fuzzy Normed Spaces
Authors: Khan Vakeel A. , Tuba Umme
Published: April 2023

The article delves into the task of formulation of meticulous sequence spaces whose elements’ convergence is a generalized version of the Cauchy convergence in the setting of intuitionistic fuzzy norm. The task of attaining a finite limit is attained via an infinite matrix operator, namely, Jordan totient operator. We discuss some topological and algebraic properties and establish some inclusion relations between the spaces.
Yamabe Solitons and τ-Quasi Yamabe Gradient Solitons on Riemannian Manifolds Admitting Concurrent-Recurrent Vector Fields
Authors: Naik Devaraja Mallesha , Fasihi-Ramandi Ghodratallah , Kumara H. Aruna , Venkatesha Venkatesha
Published: April 2023

We consider a Riemannian manifold (M,g) admitting a concurrent-recurrent vector field for which the metric g is a Yamabe soliton or a τ-quasi Yamabe gradient soliton. We show that if the metric of a Riemannian three-manifold (M, g) admitting a concurrent-recurrent vector field is a Yamabe soliton, then M is of constant negative curvature –α
2. In this case, we see that the potential vector field is Killing. Next, we show that if the metric of a Riemannian manifold M admitting concurrent-recurrent vector field is a non-trivial r-quasi Yamabe gradient soliton with potential function f, then M has constant scalar curvature and is equal to –n(n – 1)α
2. Finally, an illustrative example is presented.
A deep neural network for general scattering matrix
Authors: Jing Yongxin , Chu Hongchen , Huang Bo , Luo Jie , Wang Wei , Lai Yun
Published: April 2023

The scattering matrix is the mathematical representation of the scattering characteristics of any scatterer. Nevertheless, except for scatterers with high symmetry like spheres or cylinders, the scattering matrix does not have any analytical forms and thus can only be calculated numerically, which requires heavy computation. Here, we have developed a well-trained deep neural network (DNN) that can calculate the scattering matrix of scatterers without symmetry at a speed thousands of times faster than that of finite element solvers. Interestingly, the scattering matrix obtained from the DNN inherently satisfies the fundamental physical principles, including energy conservation, time reversal and reciprocity. Moreover, inverse design based on the DNN is made possible by applying the gradient descent algorithm. Finally, we demonstrate an application of the DNN, which is to design scatterers with desired scattering properties under special conditions. Our work proposes a convenient solution of deep learning for scattering problems.
Engineered nanoflowers, nanotrees, nanostars, nanodendrites, and nanoleaves for biomedical applications
Authors: Khakbiz Mehrdad , Shakibania Sara , Ghazanfari Lida , Zhao Shan , Tavakoli Milad , Chen Zi
Published: April 2023

The development of architectured nanomaterials has been booming in recent years in part due to their expanded applications in the biomedical field, such as biosensing, bioimaging, drug delivery, and cancer therapeutics. Nanomaterials exhibit a wide variety of shapes depending on both the intrinsic properties of the materials and the synthesis procedures. Typically, the large surface areas of nanomaterials improve the rate of mass transfer in biological reactions. They also have high self-ordering and assembly behaviors, which make them great candidates for various biomedical applications. Some nanomaterials have a high conversion rate in transforming the energy of photons into heat or fluorescence, thus showing promise in cancer treatment (such as hyperthermia) and bioimaging. The nanometric dimension makes them suitable for passing through the biological barriers or interacting with the natural molecules (such as DNA, protein). Nanoflowers, nanotrees, nanostars, and nanodendrites are examples of nano-sized structures, which exhibit unique geometry-dependent properties. Here we reviewed the fabrication methods, features, properties, and biomedical applications of four nano-structured materials including nanoflowers, nanotrees, nanostars, nanodendrites, and nanoleaves. We further provided our perspectives on employing these novel nanostructures as advanced functional materials for a broad spectrum of applications.
Middle cerebral artery dynamic cerebral autoregulation is impaired by infarctions in the anterior but not the posterior cerebral artery territory in patients with mild strokes
Authors: Bolognese Manuel , Karwacki Grzegorz , Österreich Mareike , Müller Martin , Lakatos Lehel
Published: April 2023

Objective

The aim of this study was to ascertain whether dynamic cerebral autoregulation (CA) in the middle cerebral artery (MCA) is disturbed by cerebral infarctions outside the MCA territory.

Methods

We estimated transfer function parameters gain and phase from simultaneous recordings of spontaneous oscillation in blood pressure and MCA cerebral blood flow velocity in 10 consecutive patients with isolated anterior cerebral artery (ACA) infarctions and in 22 consecutive patients with isolated posterior cerebral artery (PCA) infarctions. All ACA infarctions were in the motor, premotor, or supplementary motor cortex areas and presented with pronounced leg hemiparesis. Twenty-eight age- and sex-matched healthy subjects served as controls.

Results

Compared to controls, phase was significantly reduced in the MCA ipsilateral to the lesion site and in the contralateral MCA (unaffected hemisphere) in the very low (0.02–0.07 Hz) and low (0.07–0.15 Hz) frequency ranges in the ACA infarctions but not in the PCA infarctions. Gain was reduced only in the very low frequency range in the MCA contralateral to the ACA lesion site. Systemic factors were unrelated to phase and gain results.

Conclusion

Bilateral impairment of MCA dynamic CA in patients with a unilateral ACA infarction is frequent.