bluuebunny/crossref_metadata_2025 huggingface dataset:
AISI 440B martenzitik paslanmaz çeliğinin aşınma ve korozyon dayanımına östenitleme sıcaklığının etkisinin incelenmesi
Authors: EYİCİ Gökhan , SAKLAKOĞLU Nurşen , ÇİMEN Onur
Published: June 2023

Martenzitik paslanmaz çelikler iyi mekanik özellikleri ve orta derecede korozyon dayanımları ile diğer paslanmaz çeliklerden ayrılmaktadırlar. Belirli uygulamalarda üstün özelliklere duyulan ihtiyaç, bu çeliklerin performansının iyileştirilmesi konusunda geniş araştırmalara yol açmıştır. Bunun için ısıl işlem parametrelerinin doğru belirlenmesi önerilmektedir. Bu çalışmada AISI 440B martenzitik paslanmaz çeliğin östenitleme sıcaklığının aşınma ve korozyon dayanımına önemli ölçüde etkilediğini ortaya konmuştur. Östenitleme sıcaklığı arttıkça Cr23C6 karbürleri çözünmekte ve östenit matriste C ve Cr zenginleşmesi meydana gelmektedir. Cr zenginleşmesi korozyon dayanımını iyileştirirken, C zenginleşmesi malzeme sertliğini artırmaktadır. Ancak yüksek östenitleme sıcaklıklarında, Mf ‘in düşmesi sebebiyle kalıntı östenit miktarı artmaktadır. Aynı zamanda östenit tane irileşmesi de meydana geldiğinden, sertlikte önemli derecede azalma meydana gelmektedir. Öte yandan yüksek karbon içeriği sebebiyle martenzit fazın kristal kafesinde çarpılmalar meydana gelmekte olup, bu da koruyucu oksit filmin kararlılığını olumsuz etkileyerek korozyon dayanımını düşürmektedir. Bu çalışmada, en iyi aşınma ve korozyon dayanımı elde etmek için en uygun östenitleme sıcaklığı 1080°C olarak tespit edilmiştir.
ATENÇÃO PRIMÁRIA À SAÚDE COMO COORDENADORA DO CUIDADO NO ATENDIMENTO PRÉ-NATAL DE ALTO RISCO PARA TOXOPLASMOSE GESTACIONAL: RELATO DE CASO
Authors: Hirsch Suzana Liotto , Januskevicius Jessica de Andrade , Sgorla Felipe , Lopes Anália Rosário
Published: June 2023

Introdução: a toxoplasmose é considerada uma enfermidade com grande impacto no contexto da saúde pública, especialmente quanto à infecção primária durante a gestação e o risco de transmissão congênita. A Atenção Primária à Saúde (APS) é considerada a porta de entrada aos serviços de saúde e também a coordenadora do cuidado. Objetivo: este trabalho visa relatar um caso de toxoplasmose gestacional e a importância da APS como coordenadora do cuidado no pré-natal de alto risco. Relato do caso: trata-se de uma quartigesta, 27 anos de idade, de cor parda, atualmente desempregada e residente em área de vulnerabilidade sociodemográfica. Iniciou seu pré-natal tardiamente, sendo realizado seu primeiro atendimento com idade gestacional de 17 semanas e 5 dias. Esse caso foi observado e acompanhado durante o período do internato médico em APS I que ocorre no nono e décimo período do curso de medicina de uma universidade federal localizada em município de médio porte. Resultados: esta experiência possibilitou o aprendizado sobre o tratamento e protocolo da toxoplasmose gestacional na APS, a articulação com a atenção especializada e funcionamento da rede. Considerações finais: a toxoplasmose gestacional e consequente transmissão transplacentária, permanece no cenário epidemiológico como uma das doenças que impactam na saúde fetal e neonatal com graves consequências para o indivíduo na vida adulta, e a APS desempenha papel primordial quanto a elaboração de medidas preventivas, no planejamento reprodutivo, na captação precoce da gestante para o início do pré-natal e como a principal coordenadora do cuidado nos casos diagnosticados de toxoplasmose gestacional.
DRIMYS (CATAIA, CANELO, QUIEBRA-MUELAS): UMA REVISÃO LITERÁRIA SOBRE SUA FITOQUÍMICA, ATIVIDADES BIOLÓGICAS, FARMACOLÓGICAS E TOXICOLÓGICAS
Authors: Oshiro Mariana Cardoso , De Souza Ivone Antônia
Published: June 2023

Drimys é um dos gêneros mais conhecidos da família botânica Winteraceae. As espécies que compõe este gênero têm sido amplamente utilizadas na medicina popular latino americana para o tratamento de malária, dores gástricas, dor de dente, anemia, entre outros. Além do mais, em algumas localidades, as folhas secas e as bagas dos frutos são utilizadas na culinária como condimento pois possuem sabor apimentado. O objetivo deste trabalho foi realizar uma revisão sistemática sobre a fitoquímica, atividades biológicas, farmacológicas e toxicologicas das espécies do gênero Drimys. Para isso, foram realizadas buscas em diferentes plataformas, no período de 1987 e 2022, utilizando-se a palavra “Drimys”, indicativa do gênero botânico, acompanhado dos descritores: “Winteraceae”, "pharmacology”, “neoplasm”, “inflammation”, “insecticides”, “clinical trial”, “pain”, “food”, “ulcer”, “malaria” e “toxicity”. Incluiu-se trabalhos sobre o perfil fitoquímico, atividades biológicas e potencial farmacológico. Foram selecionados 77 artigos científicos sobre as espécies D. winteri, D. brasiliensis, D. angustifolia, D. granadensis e D. piperita com informações de estudos in vivo e in vitro que possibilitam o conhecimento medicinal, a conservação e o uso sustentável destas espécies.
O PRÉ NATAL PSICOLÓGICO COMO INTERVENÇÃO PREVENTIVA NO PERÍODO GRAVÍDICO PUERPERAL: UMA REVISÃO INTEGRATIVA DA LITERATURA
Authors: Araújo Natiely Dias Sousa , Leite Bruna de Melo Oliveira
Published: June 2023

Ser mãe é um marco do desenvolvimento psicológico da mulher. Desse modo, a partir da confirmação da gravidez, há a necessidade de uma reestruturação e reajustamento de sua vida, com o intuito de tornar a experiência mais segura para mãe e filho. Sendo assim, a presente pesquisa tem como finalidade compreender os impactos emocionais no período gravídico puerperal, bem como investigar os efeitos do pré-natal psicológico na redução de possíveis psicopatologias que afetam mulheres no período reprodutivo. Em relação a metodologia, trata-se de uma Revisão Integrativa de literatura, sendo utilizadas as plataformas Biblioteca Virtual em Saúde (BVS), Scielo, Capes Periódicos (CAPES) e Periódicos e Eletrônicos em Psicologia (PePSIC), aos descritores foram: Gestação; Puerpério; Acompanhamento psicológico, Pre natal Psicológico. Como resultado, houve a síntese dos artigos com a realização de um quadro incluindo as seguintes informações: autor; ano da publicação; título; metodologia; resultados e conclusão, tais artigos foram organizados por números de forma crescente. Conclui-se, que o pré-natal psicológico é indispensável, pois têm como objetivo principal buscar formas de melhorar o momento do parto e a experiência dessa nova fase, por meio da oferta de programas parentais que incluam ações educativas e aspectos psicodinâmicos.
Legal Regulation of Employment in a Digital Society
Authors: Filyushchenko Lyudmila Ivanovna
Published: June 2023

The subject of this study is the legal norms that mediate the procedures for the selection of personnel and the employment of employees. The purpose of the study is to analyze the norms of labor legislation regulating employment relations in a digital society, and the practice of their application. General and private scientific methods were used (formal dogmatic, comparative legal methods of research, interpretation, modeling). The positive role of digital platforms in the employment of citizens was noted. However, the development of digital technologies displaces people from the sphere of employment, to which the legislation is still weakly responding. Particular attention is paid to employment issues that have not been resolved in legislation, which may lead to a deterioration of the situation of citizens. The transformation of labor functions is taking place, which excludes human participation in part of operations and makes it necessary to consolidate in legislation the obligation of employees to improve their qualifications. The content of the concept of "business qualities" of an employee is expanding, including digital competencies, including the ability to interact with artificial intelligence. It is desirable to reflect the definition of the concept in legislation and take it into account when posting information about vacancies on digital platforms. The conclusion is made about the inadmissibility of making a decision on employment (refusal of admission) by artificial intelligence on the basis of data collected without the consent of the applicant. The legislation in the field of employment is not quite ready to respond to the changes taking place in connection with digitalization. The proposed solutions may be the subject of discussion and useful for the legislator.
Features of persons with leadership status in the criminal environment
Authors: Novozhilov Sergei Sergeevich
Published: June 2023

The article highlights the main problems associated with the definition of persons with leadership status in the criminal environment, the categories of persons are considered: "thief in law", "poser", "looker" and their place in the criminal hierarchy. The position of persons who are the leaders of organized criminal communities (OPS), who do not have the specified criminal statuses, but occupy the highest position in the criminal hierarchy of the OPS created by them, is disclosed. The article also considers the position in the criminal hierarchy of "thieves in law", deprived by the decision of the thieves' meeting of status leadership (uncrowned), "thieves in law" retired (proshlyakov). The author raises the question of the ability of persons of this category to occupy the highest position in the criminal hierarchy (to be subjects of crimes provided for in Part 4 of Article 210 and Article 210.1 of the Criminal Code of the Russian Federation).   In the course of the analysis, the author comes to the conclusion that the criminal hierarchy on the outside is not identical to the prison criminal hierarchy (penitentiary), and a person who occupies a sufficiently high criminal status in the prison hierarchy, after being released and joining a criminal community (criminal organization), may not occupy a leading position there. The author also gives arguments that such persons as "poser" and "looker" occupy the highest position in the criminal hierarchy only if they are the leaders of OPS and EOPS, having a multi-level hierarchy in their structure with the presence of a higher position in it, in all other cases, according to the author, persons of this category do not occupy the highest, and the "high" position and subjects of Part 4 of Article 210 and Article 210.1 of the Criminal Code of the Russian Federation are not.
Guardians of Hearth in the Russian and Chinese mythological traditions
Authors: Popova Anastasiia , Serebryakova Anastasiia Igorevna
Published: June 2023

One of the most frequently encountered characters in the mythology of various cultures are household spirits, deities-guardians of the hearth, who have lived side by side with humans since ancient times. In this article, on the basis of Russian and Chinese sources, the authors conduct a comparative analysis of the images of the patrons of the household in such aspects as the names given to them by the bearers of culture, versions of origin, appearance, marital status, functions that these deities performed, rituals of worship. The subject of the research is the images of the Domovoy and God of the hearth of Zao-wang in Russian and Chinese cultures. The aim of the work is to find similarities and differences about Domovoy and Zao-wang, to comprehend the interaction of a person with the domestic spirit in Russia and China, which is relevant in the light of the strengthening of relationship between the two countries and contributes to a better understanding of both Chinese and Russian culture. The novelty lies in the absence of such a comparative study in Russian science. As a result of the work, it was revealed that the characters of the keeper of the hearth in the Russian and Chinese traditions have both similarities and differences. Similar features of home spirits are due to global cultural processes, while their differences are determined by worldview and other features of the regions.
Relaciones humanos-coyotes en la provincia de Cartago, Costa Rica
Authors: Barboza-Arias Luis
Published: June 2023

En este ensayo indago las relaciones entre humanos y coyotes en la provincia de Cartago, en Costa Rica. Mi punto de partida es el incremento en la cantidad de avistamientos de individuos de esa especie en los espacios urbanos y semiurbanos, un fenómeno que tiene lugar desde el período del confinamiento social (primer semestre de 2020) provocado por la pandemia de COVID-19. En la construcción del caso empírico incorporo mi experiencia de trabajo de campo con la comunidad rural de San Gerardo de Oreamuno (zona norte de Cartago). En esa localidad, analizo la conformación de un territorio de (co)existencia a partir de lo que llamo «ecologías de proximidad». El conjunto de estas reflexiones explora las formas situadas en que la presencia-coyote crea posibilidades para organizar nuevos relatos sobre la (co)habitabilidad multiespecie, desvelando el surgimiento de modos particulares de relacionamiento que tensionan las narrativas antropocéntricas de progreso, desarrollo y sostenibilidad que imperan en la actualidad.
Riscos Potenciais à Saúde Humana e Ambiental com o uso do Mercúrio na Atividade de Garimpo Artesanal de Ouro no Alto Rio Madeira, Amazônia Ocidental
Authors: Monte Junior Roberto Pinto , Bastos Wanderley Rodrigues , Coutinho Isabela Esteves Cury , Sousa Filho Izidro Ferreira de
Published: June 2023

Objetivo: Apresentar resultados recentes sobre a existência de mercúrio nos compartimentos no metabolismo humano, provocados em razão da exploração de ouro na área de proteção ambiental do Rio Madeira, e registrar as mudanças na legislação referente a atividade de garimpo de ouro. Revisão bibliográfica: O alto rio Madeira, especialmente na Área de Proteção Ambiental (APA), tem sido impactado em decorrência das atividades relacionadas ao exercício do garimpo de ouro artesanal, desmatamento e queimadas, esses para extração de madeira, agropecuária e projetos hidrelétricos. Todas essas atividades acabam contribuindo para a liberação e ciclagem de mercúrio (Hg) no ecossistema amazônico e, consequentemente, colocando em risco de exposição ao metilmercúrio (MeHg) a população tradicional ribeirinha. Considerações finais: Do ponto de vista da exposição humana ao MeHg deve-se adotar os procedimentos de monitoramento promovidos pela área de saúde, especialmente às comunidades ribeirinhas mais isoladas que poderia estar conectado ao programa de Saúde da Família.
A FANCA mutation carrier with enhanced toxicity to cancer directed treatment - A case report and review of literature
Authors: Vallathol Dilip Harindran , Vijayagopal K. S. , Sajeevan K. V.
Published: June 2023

Chemotherapy and radiotherapy are backbones of cancer treatment. Genome instability syndromes are rare but an essential factor to be identified early in the treatment of malignancies. It can lead to the occurrence of multiple malignancies and impede treatment due to undue hypersensitivity, leading to extreme and often fatal toxicities. We, hereby, report a case of a middle-aged lady who was diagnosed with a carcinoma of the head and neck and planned for treatment with neoadjuvant chemotherapy followed by surgery or chemoradiation. However, she developed severe toxicity to all forms of treatment for cancer. Her gene-based panel screening test revealed a Fanconi anaemia, complementation group A (FANCA) gene abnormality which is associated with an autosomal recessive mode of inheritance. This case outlines the importance of considering the possibility and a high index of suspicion of a hereditary basis in cases of relatively early-onset malignancy before defining an oncological treatment strategy. The paucity of data except for case reports limits evidence-based management in such cases and requires a collective effort for treatment.
A study of NSC listed companies in India: capital structure and financial performance
Authors: Negi Manoj Singh , Sethi Amanjeet Singh
Published: June 2023

A decision that can affect a firm performance is the selection of its capital structure. To maximize a firms’ profit or to check the ability of a firm in gung-ho situations, capital structure decisions play a very important role. The expectations of the shareholder towards the firms performance are closely correlated with its capital structure decisions. Capital structure is a technique of a firm to finance its assets and for this, company uses the mixture of equity and debt. In this study, the researchers investigated the association between capital structure and financial performance of the NSC listed companies from 2017-2018 to 2021-2022. DR is negatively correlated with EPS and ROE but shows significant relationship with GP and NP which means there is a positive correlation with financial performance. In the same way DER is positively correlated with all the financial performance measures i.e. GP, NP and EPS except ROE. The R square value of GP, NP, ESP and ROE ratios represents 25.5%, 35.1%, 32.4% and 73.9% experimental deviation in the financial performance elucidated by the variations in two independent variables i.e. DR and DER ratio.
Knowledge Management and Organizational Performance - Employee Perception: A Research on Commercial Banks in Rangamati
Authors: Farha Sultana
Published: June 2023

Competitions are escalating day by day forcing businesses to use knowledge management to increase organizational effectiveness. To collect primary data, the study used a survey approach with a questionnaire. The study's target populations were the staff members of a few particular banks in Rangamati, Bangladesh. Using the multiple regressions approach, two hypotheses were created and evaluated. The study's results show that knowledge management has a positive effect on organizational performance. According to the study, knowledge management significantly affects organizational performance. In the study, a substantial positive relationship between knowledge management drivers and knowledge management performance was found. It is advised that banks and other companies use knowledge management to successfully accomplish corporate goals and make sure that staff members are welltrained and developed to acquire the necessary information to successfully handle modern issues.
Acute Kidney Injury Following Caesarean Section: A Case Report
Authors:   Department of Obstetrics & Gynaecology, Mildura Base Public Hospital, Australia, K Kathawadia , A Aboda ,   Department of Obstetrics & Gynaecology, Mildura Base Public Hospital, Australia, N Khanal ,   Department of Obstetrics & Gynaecology, Mildura Base Public Hospital, Australia, B McCully ,   Department of Obstetrics & Gynaecology, Mildura Base Public Hospital, Australia
Published: June 2023

Acute Kidney Injury (AKI) is an infrequent pregnancy complication, often associated with Nonsteroidal Anti-Inflammatory Analgesics (NSAIDs) during the postpartum period. In this case study, a multiparous, 27-year-old woman presented to the Emergency department on day six after an uncomplicated Caesarean section with severe lower back pain. She was diagnosed with AKI and was admitted for management under a multidisciplinary team. Following appropriate treatment, she was discharged with complete recovery. Managing AKI postpartum requires meticulous and collaborative intervention to prevent potential long-term complications.
5,6-Fused Heterocycle Cholate Derivatives as Spore Germination Inhibitors of Clostridioides difficile
Authors: Sharma Shiv , Phan Jacqueline , Abel-Santos Ernesto , Firestine Steven
Published: June 2023

Clostridioides difficile infection (CDI) is an anaerobic bacterium that is responsible for most antibiotic-associated cases of diarrhea. CDI begins with the ingestion of an environmentally stable spore that germinates within the GI tract under specific conditions. We have shown that the bile salt analog N-phenyl-cholan-24-amide (1) can inhibit spore germination and prevent CDI in animal models of infection. Unfortunately, 1, was stable in the gut of antibiotic-treated animals but was rapidly degraded by gastrointestinal micoflora in the normal gut preventing its use to prevent CDI. We hypothesized that the source of the instability was the amide group. To explore this hypothesis, we removed the amide by either converting it to an amine or to 5,6-fused heterocycles. We found that reduction of the amide to an amine resulted in a significant loss of activity, but conversion to benzimidazole (6a), benzothiazole (6b), or benzoxazole (6c) gave compounds with good antigermination activity. Exploration of other sterane groups such as chenodeoxycholate and deoxycholate gave active compounds only for the benzimidazole series. Examination of 6b showed that it was stable for 24 hours in the presence of feces taken from healthy mice validating the hypothesis that an amide bioisostere would increase the stability of the compound. Mice treated with 6a and 6b also showed no signs of toxicity up to 300 mg/kg daily for 7 days. Each compound was tested for its ability to prevent CDI in a murine model. Compound 6b but not 6a was able to prevent CDI when given at a dose of 50 mg/kg.
Critical Assessment of pH-Dependent Lipophilic Profiles of Small Molecules for Drug Design: Which One Should We Use and In Which Cases?
Authors: Bertsch Aguilar Esteban , Suñer Sánchez Sebastián , Pinheiro Silvana , Zamora Ramírez William J.
Published: June 2023

Lipophilicity is a physicochemical property with wide relevance in drug design and also applied in areas such as food chemistry, environmental chemistry, and computational biology. This descriptor strongly influences the absorption, distribution, permeability, bioaccumulation, protein-binding, and biological activity of bioorganic compounds. Lipophilicity is commonly expressed as the n-octanol/water partition coefficient (PN) for neutral molecules, whereas for molecules with ionizable groups, the distribution coefficient (D) at a given pH is used. The logDpH is usually predicted using a pH correction over the logPN using the pKa of ionizable molecules, while often ignoring the ionic partition (PI) because of the challenge of predicting the partitioning of the charged species. In this work, we studied the impact of PI on the prediction of lipophilicity of small drug-like molecules by modeling 225 logDpH of a set of experimental values using both the formalism that takes into account a pH correction (see Eq. 1) and the one considering the partition of ionic species (see Eq. 2). Our findings show that a better calculation is obtained by considering the ionic partition while ignoring its contribution can lead to inadequate computational predictions. In this context, we developed machine learning algorithms to determine in which cases the PI should be considered. The results indicate that small, compact, and hydrophobic molecules with a higher likelihood of being in their ionic state at specific pH values, were better modeled using Eq. 2. Finally, we validated our findings using a test and external set where the logistic regressions, random forest classifications, and support vector machine models predicted the better formalism to determine the logDpH for each molecule with high accuracies, sensitivities, and specificities.
Teaching biologics formulation using molecular modeling and simulations
Authors: Phillips Andrew , Srinivas Anusha , Prentoska Ilina Prentoska , O'Dea Margaret , Kustrup Matthew , Hurley Sarah , Bruno Savannah , Nguyen Vy , Lai Pin-Kuang
Published: June 2023

Teaching chemistry and chemical engineering students about biologics formulation remains challenging despite its increasing importance in pharmaceutical development. Monoclonal antibodies, commonly called mAbs, are the most popular biologics. They have been developed into drugs to treat various diseases in the past decades. Multiple challenges exist for designing proper formulations to stabilize mAbs, such as preventing aggregation and mitigating viscosity. Molecular modeling and simulations can improve pharmaceutical products by examining the interactions between mAbs and other compounds, such as excipients. To introduce students to biopharmaceuticals, eight chemical engineering students at the Stevens Institute of Technology participated in a semester-long course to learn the challenges of pharmaceutical development and different computational skills to study biologics formulation. The students started with a limited background in this field. Throughout one semester, they were introduced to various literature and software tools for modeling antibodies and studying their interactions with excipients. Positive learning outcomes were achieved through pre- and post-course assessments. This paper aims to develop a course structure to be replicated at other universities and institutions to teach biopharmaceutical development to students.
Targeting G-quadruplex in SARS-CoV-2 RNA Genome with Tetraphenylethene Derivatives for Antiviral Therapy
Authors: Gupta Payal , Khadake Rushikesh , Mirgane Harshad , Bhosale Sheshnath , Gupta Dharmender , Vrati Sudhanshu , Rode Ambadas
Published: June 2023

Targeting genomic RNA conformations that are crucial for SARS-CoV-2 replication is a promising antiviral strategy. Herein we have developed tetraphenylethene (TPE) derivatives to target RNA G-quadruplexes (RGQs) present in the SARS-CoV-2 nucleocapsid gene ORF. Our EMSA, fluorescence and CD data suggests the binding of two TPE derivatives i.e., TPE−MePy and TPE-AllylPy, with RGQ derived from SARS-CoV-2 nucleocapsid gene. In addition, in vitro luciferase assay demonstrated suppression in translation efficiency by 3.86-fold and 2.89-fold in presence of TPE-MePy and TPE-AllylPy, respectively. Subsequently, the cytotoxicity and immunofluorescence-based antiviral assay in VeroE6 cells indicated 82% inhibition in SARS-CoV-2 nucleocapsid gene expression without any effect on cell viability. These results highlight the promising use of TPE derivatives as an antiviral drug to alter the crucial genes expression in SARS-CoV-2 as well as other viruses.
A chemically self-charging flexible aqueous Zinc battery using a covalent organic framework cathode
Authors: Liu Qi , Chen Xiaojuan , Ma Yanwei , Lu Yiwen , Zhang Huimin , Yang Baozhu
Published: June 2023

The development of novel high performance organic cathode materials is the focus of research in aqueous Zn-organic batteries. Covalent organic framework (COF) is a new type of crystalline porous polymer with the advantages of large capacity, flexible structural design and low solubility in electrolyte. It is considered as a promising cathode material for zinc battery. In this study, a novel nitrogen-heterocyclic covalent organic framework COF material (HTAQ-COF) with abundant redox active sites of C═N and C═O was designed and synthesized, which was successfully applied to the cathode of aqueous Zn battery. The constructed HTAQ-COF cathode exhibits a high discharge specific capacity of 305 mA h g-1 at 0.04 A g-1 with excellent cycle life and high rate-performance, and a high energy density of 135 Wh kg-1. In addition, the fabricated flexible aqueous Zn//HTAQ-COF batteries also exhibited excellent long-cycle stability (about 87% capacity retention after 1000 cycles at 2.0 A g-1). At the same time, the flexible aqueous Zinc battery can be effectively charged by harvesting pervasive energy from the ambient air. After air-charging for 30 h, the discharged flexible Zn//HTAQ-COF battery can be self-charged to 1.2 V around without any external power supply, deliver a considerable discharge capacity of 279 mA h g-1, display a high-rate performance and the higher chemically self-charging stability. More importantly, this air-rechargeable flexible Zn//HTAQ-COF batteries are compatible with different chemical or/and galvanostatic charging hybrid modes. This work provides a new way to develop energy storage systems that are not limited by the power supply environment.
Scalable air-tolerant μL-volume synthesis of thick poly(SPMA) brushes using SI-ARGET-ATRP
Authors: Veldscholte Lars , de Beer Sissi
Published: June 2023

We present a straightforward procedure for preparing thick (up to 300 nm) poly(3-sulfopropyl methacrylate) brushes using SI-ARGET-ATRP by conducting the reaction in a fluid film between the substrate and a coverslip. This method is advantageous in a number of ways: it does not require deoxygenation of the reaction solution, and the monomer conversion is much higher than usual since only a minimal amount of solution (microliters) is used, resulting in a tremendous reduction (~50x) of wasted reagents. Moreover, this method is particularly suited for grafting brushes to large substrates.
Substrate-selective catalysis enabled synthesis of azaphilone natural products
Authors: Wang Ye , Torma Katherine , Pyser Joshua , Zimmerman Paul , Narayan Alison
Published: June 2023

Achieving substrate-selectivity is a central element of nature’s approach to synthesis; relying on the ability of a catalyst to discriminate, based on small structural changes, which molecules will move forward in a synthesis. This approach can be challenging to duplicate in the laboratory, but can be powerful when realized. In this work, substrate-selective catalysis is leveraged to discriminate between two intermediates that exist in equilibrium, subsequently directing the final cyclization to arrive at either the linear or angular tricyclic core common to subsets of azaphilone natural products. By using a flavin-dependent monooxygenase (FDMO) in sequence with an acyl transferase (AT), the conversion of several orcinaldehyde substrates directly to the corresponding linear tricyclic azaphilones in a single reaction vessel was achieved. Furthermore, mechanistic studies support that a substrate equilibrium together with enzyme substrate-selectivity play an import role in the selectivity of the final cyclization step. A panel of azaphilone natural products and derivatives thereof were synthesized using this strategy.
Solution of the Inverse Problem Describing Slow Thermal Convection in a Rotating Layer
Authors:   Institute of Computational Modeling SB RAS, Andreev V. K. , Latonova L. I.
Published: June 2023

The linear inverse initial-boundary value problem arising when modeling the rotational motion of a viscous heat-conducting liquid in a flat layer is solved. It is shown that the problem has two different integral identities. Based on these identities, a priori estimates of the solution in a uniform metric are obtained and its uniqueness is proved. The conditions for the input data are also determined, under which this solution goes to the stationary mode with increasing time according to the exponential law. In the final part, the existence of a unique classical solution of the inverse problem is proved. To do this, differentiating the problem by a spatial variable, we come to a direct non-classical problem with two integral conditions instead of the usual boundary conditions. The new problem is solved by the method of separation of variables, which makes it possible to find a solution in the form of rapidly converging series on a special basis.
Pengelolaan Sampah Anorganik Melalui Bank Sampah Terhadap Peningkatan Kesejahteraan Desa Plandaan Kecamatan Plandaan
Authors: Hadi Sucipto  , Farikha Setiadi
Published: June 2023

Plandaan Village is experiencing an emergency and the absence of a Garbage Disposal Site (TPS) is trying to overcome this condition. Garbage is a very important problem, because it has an impact on the environment so it needs attention from all elements, both from the Village Government and the community. This community service activity aims to optimize the management of inorganic waste through the Garbage Bank. This community service activity was carried out intensively for 1 month February 2023 with a schedule that had been agreed upon between the writing team and the fostered partners and there were developments in Plandaan village. From the results of intensive activities that have been carried out, satisfactory results were obtained. Foster partners are able to follow up on cooperation with the Indonesian Jombang Garbage Bank. From the results of the community service activities that have been carried out, it is hoped that this program can be continued by the local village government so that the fostered partners will develop further.

Keywords: Garbage, Garbage Bank, Waste Management
Pengembangan Digital Marketing Untuk Produk “UMKM Bilqis Fresh” Di Desa Karangdagangan
Authors: Lilik  , Sinta A Paramita
Published: June 2023

Karangdatangan Village has a lot of potential for Micro, Small and Medium Enterprises, especially in Dusun Doro there is one of the drivers for MSME products for lemon bilqis fresh drink, but the marketing potential for this product can be said to be less than optimal. This community service activity in Karangdatangan Village, especially in Dusun Doro, aims to optimize the marketing of lemon drink products through digital marketing practices so that they become products that have economic value. This PKM activity was carried out intensively for 1 month in February 2023 with a schedule agreed between the writing team and the fostered partners. From the results of intensive socialization activities and digital marketing practices that have been carried out, satisfactory results can be obtained. Foster partners can be said to be able to increase sales turnover and expand market segmentation through online marketing via shopee, tiktok, and Instagram. Partners also have their own NIB and PIRT and have their own product logo. From the results of the activities that have been carried out, it is hoped that this program can be continued by the local Village Government so that the fostered partners will develop further.

Keywords: Strategy, development, MSMEs, SWOT.
Justice, at what cost? Exploring the Lived Experiences of Female Crown Prosecutors Working with Sexual Violence Trauma in New Zealand’s Criminal Law
Authors:   , Te Miha Taine
Published: June 2023

The criminal justice system (CJS) is undeniably a trauma-permeated environment as it functions to oversee the pursuit of justice in criminal cases that capture the darkest sides of humanity. However, little attention has been paid to the impacts of this trauma exposure on legal professionals. In New Zealand (NZ), Crown prosecutors (CPs) play a unique role in the CJS, working predominantly with serious violence and sexual violence offences. This role therefore comes with distinct responsibilities and stressors, as well as continuous occupational exposure to traumatic material. However, CPs have been largely neglected from vicarious trauma (VT) research. Female CPs who work predominantly with sexual violence trauma are arguably at an increased risk of developing adverse psychological consequences, as preliminary empirical evidence has indicated that sexual violence trauma has a particularly profound impact on legal professionals, and that female professionals may have a greater susceptibility to the development of VT than males; yet no research to date has focused on female CPs. The current study seeks to qualitatively explore the lived experiences of six female CPs working with sexual trauma in the NZ CJS. Data was analyzed using Interpretative Phenomenological Analysis. Three themes were developed from the data: Navigating the Emotional and Legal Aspects of the Role Without a Compass, The Added Impacts of Working with Sexual Trauma, and Factors Influencing Wellbeing and Help Seeking. These themes highlighted that female CPs experience significant psychological impacts due to role-specific occupational stressors and exposure to traumatic material. Working with sexual trauma had an added impact for female CPs and was found to exacerbate the existing difficulties and consequences of working with traumatic material more broadly. Further a range of individual, professional and organizational factors functioned to either alleviate or exacerbate these stressors and impacts, with the most salient exacerbator being the lack of effective organizational support. These findings contribute to the small amount of extant research on legal professionals’ wellbeing. Legal policy and practice must recognise the specific impacts of working in the criminal law and appropriately respond to this. Effective policy and practice that addresses the unique experiences of female CPs who work with sexual trauma is urgently required, to protect their psychological wellbeing from the gendered and occupational risks they experience in the CP role.
O DISCURSO DE MAIS PRÁTICA PARA MELHOR FORMAR O PROFESSOR
Authors: Da Conceição Giselle , Borges Veronica
Published: June 2023

Este artigo tem a pretensão de discutir como a prática tem sido significada, no cenário brasileiro, em meio a disputas no campo da formação de professores. Adotamos como estratégia teórico-prática a perspectiva discursiva a partir da Teoria do Discurso de Ernesto Laclau e Chantal Mouffe. O foco está na discursividade dos Pareceres e das Resoluções das três últimas Diretrizes Curriculares Nacionais brasileiras voltadas para a Formação de Professores da Educação Básica em nível superior dos anos de 2002, de 2015 e de 2019. Argumentamos sobre os pontos nodais discursivos que têm sustentado a manutenção do discurso de mais prática para melhor formar o professor em três políticas curriculares elaboradas e promulgadas durante governos de tendências político-partidárias distintas. São eles: cursos de licenciatura com identidade própria; formação em nível superior para todos os professores; aproximar as Instituições de Ensino Superior e os Sistemas de Ensino da Educação Básica; e associação adequada entre teoria e prática. As considerações finais ressaltam que os textos políticos que compuseram o corpus de análise foram pensados como parte de um meio social que é todo ele político e, portanto, foram considerados como resultantes da grande arena de disputas que é o social.  A aposta em investigar tais disputas implica criar uma gramática própria com a pretensão de discutir as relações entre discurso e produção de discursos de maneira não dicotômica e não essencialista, considerando o social não como um todo que está fragmentado, mas como uma pluralidade de elementos discursivos que se constituem na ação política.
EDUCAÇÃO ESCOLAR QUILOMBOLA E OS QUILOMBOS: O PROTAGONISMO DOS MOVIMENTOS SOCIAIS QUILOMBOLAS
Authors: Cruz Queziane Martins da , Ramos dos Santos Arlete
Published: June 2023

Neste trabalho investigou-se o atual cenário da Educação Escolar Quilombola (EEQ) no contexto da Educação do Campo. Em seguida, discutimos a importância e atualidade de pautar a formação de professores para a EEQ à luz das mais recentes normatizações instituídas. Discorremos também sobre as concepções e perspectivas teóricas de referência, com o intuito de compreender a materialidade das Políticas Públicas de Educação Ambiental articulada à Pedagogia Histórico-Crítica nas escolas quilombolas do município de Bom Jesus da Lapa. Elencamos às contradições existentes com a implantação da Base Nacional Comum Curricular (BNCC) e interlocuções dos programas do Plano de Ações Articuladas (PAR).   Optamos pela metodologia do Materialismo Histórico dialético (MHD)e suas categorias foram empregados como referenciais de análise. Os procedimentos de pesquisa foram organizados em análise documental, pesquisa bibliográfica, questionários e entrevistas. A partir do desenvolvimento e análise de investigação verificamos os contextos e perspectivas de professores atuantes na Educação Quilombola campesina, nas escolas do Ensino Fundamental. Concluímos que no referido município ocorre um movimento diferenciado para fortalecer as especificidades da EEQ e respeitar a diversidade do povo campesino quilombola.
O TRANSPORTE ESCOLAR NAS RODAS DE CONVERSA DO FOPINECAF: DESAFIOS DE ACESSO DE ESTUDANTES ÀS ESCOLAS DO CAMPO
Authors: Dos Santos Prata Bruna , De Souza e Souza Érica , Maria Leite Nogueira Eulina
Published: June 2023

O artigo objetiva apresentar os desafios de acesso de estudantes às escolas do campo em relação ao transporte escolar do município de Parintins/AM. Trata-se de um estudo desenvolvido com apoio da pesquisa bibliográfica, observação participante e rodas de conversa do Fórum Parintinense de Educação do Campo, das Florestas e das águas Paulo Freire (FOPINECAF), realizadas entre 2017 a 2019, cuja metodologia baseia-se na escuta e diálogo com estudantes, pais, professores/as e trabalhadores/as do campo sobre realidade da Educação do Campo em Parintins. Os resultados evidenciam que em Parintins, o transporte escolar é predominante fluvial, tem interferência da dinâmica e ciclo das águas, são os processos do fenômeno natural que influencia o deslocamento dos estudantes e, embora este seja uma política importante para o acesso e permanência de estudantes de escolas do campo, há fragilidades na execução e acompanhamento dos serviços por parte da Secretária Municipal de Educação (SEME/PIN), no que se refere as condições precárias das embarcações, segurança e atendimento.
A DESINFORMAÇÃO E OS DISCURSOS AUTORITÁRIOS: A DEMOCRACIA AMEAÇADA E O DESAFIO À EDUCAÇÃO
Authors: Grutzamann Lidiane , Schilling Flávia
Published: June 2023

O texto propõe uma reflexão sobre a desinformação enquanto pressuposto de veiculação de discursos autoritários com alto poder de sedução das novas gerações hiper conectadas. Hannah Arendt (2016a, 2016b,1989) analisou a comunicação política no nazismo e verificou a presença de mentiras, entre outras estratégias de manipulação em prol de um projeto autoritário. O exercício demonstrou que a análise das técnicas de comunicação política mostra-se eficiente na identificação e prevenção a ascensão de novos autocratas. No discurso “Aspectos do novo radicalismo de direita”, proferido aos estudantes da Universidade de Viena, Adorno (2020) apresenta a propaganda como um mecanismo eficaz de transformação de mentiras em verdades, explica seu funcionamento e os principais truques de manipulação amplamente utilizados pelos movimentos extremistas antidemocráticos. É de extrema importância a divulgação destes indicadores diante do início da digitalização da política, conforme nos atualiza a antropóloga Cesarino (2019, 2020 e 2021). A mesma nebulosidade que impede a diferenciação da verdade e da mentira nos novos espaços de comunicação política disfarça o discurso com potencial autoritário e se configura como risco à democracia e um grande desafio à educação das novas gerações. No sentido de contribuir com a reflexão, criamos uma tabela comparativa das principais técnicas de manipulação discursiva presentes no extremismo da década de 30 e a evolução destas estratégias em tempos de cibernética. Este recurso pretende servir de subsídio informativo para criação de estratégias didáticas para prevenção de novos extremismos e fortalecimento dos processos democráticos.
O TRABALHO EDUCATIVO COM PROJETOS NA EDUCAÇÃO DO CAMPO
Authors: Carvalho Wirla Risany Lima , Barroso Rodrigues Disnah , Almeida Melo Keylla Rejane
Published: June 2023

A partir da luta dos movimentos sociais do campo, foram idealizadas leis e políticas públicas destinadas às populações camponesas, como a Educação do Campo, assegurando a esses sujeitos suas especificidades e necessidades. Essas iniciativas no Brasil datam de menos de três décadas. Faz-se necessário um processo de (re)afirmação dessas políticas e da valorização permanente do campo, sendo a educação uma condição humana fundamental nesse processo. Não qualquer tipo de educação, mas aquela pensada pelo/para/com os próprios camponeses, com viés crítico. O objetivo deste artigo é discutir o trabalho educativo com projetos para a Educação do Campo, fundamentado nos estudos produzidos sobre a Educação do Campo, suas bases legais, a Pedagogia Histórico-Crítica e a Pedagogia da Alternância. Especificamente, apresenta-se uma proposta pedagógica de trabalho educativo com projetos para a Educação do Campo. O referencial teórico teve como base os estudos de Caldart (2019), Saviani (1983; 2016) e Vasconcellos (2014a e 2014b), entre outros. Esta proposição atingiu sua intencionalidade de relação teórico-prática com a proposta pedagógica de trabalho educativo com projetos para a Educação do Campo, focalizando nos aspectos primordiais dos modos de ser e viver no/do campo. Mostrou-se proveitosa oportunidade de criar uma proposta a ser aplicada nas escolas do campo, envolvendo os/as professores/as, os/as alunos/as, as famílias e a comunidade, para fortalecer o campo enquanto espaço de vida e de trabalho de sujeitos sociais. Espera-se ampliar os espaços de discussão, renovação de ideias e materialização dos princípios, conceitos e práticas da Educação do Campo, sobretudo, uma valorização da identidade campesina.
Comparison of Effective Mentoring Frameworks for Transitional-Aged Youth in Educational Settings
Authors:   , Fitz Lawrence
Published: June 2023

Every child deserves the opportunity to succeed. Mentoring and mentoring programs are believed to be an important community and educational initiative. It is incumbent upon educators to prepare and equip young people to meet the challenges of adulthood and achieve their full potential. The purpose of this study was to determine the program inputs that contribute to transitional-aged youth mentees’ outcomes from mentoring. Strategies from formal, informal, and natural mentoring frameworks were considered. Mentoring programs’ impact on resilience was also assessed. A qualitative comparative document analysis, grounded in the principles of mentoring frameworks, was utilized to determine strategies of mentoring programs’ effectiveness. The researcher identified secondary resources to gather information on mentoring frameworks for youth. Data analysis and results from peer reviewed articles on mentoring frameworks were presented. Dissertations with research foci on the efficacy of mentoring programs were analyzed and compared. The research sought to answer, in general, why effective mentoring frameworks are needed in transitional-aged youth’s educational settings. The coding exercises and creation of the codebook were achieved through utilization of Nvivo, a computerized qualitative coding software program, as well as memo entries and handwritten notes. Emergent themes and subcodes of 1) Elements of Mentoring Relationships; 2) Types of Youth; 3) Mentor Type; 4) Mentoring & Intervention Strategies; 5) Mentoring Impact & Outcomes for Mentees; 6) Mentoring Frameworks; and, 7) Mentor Selection Characteristics resulted from the thematic content analysis. Specific characteristics that emerged were 1) Mentor Selection; 2) Elements of Mentoring Relationships; 3) Relationship Quality; and, 4) Relationship Intensity. The research revealed that there are specific strategies of formal, informal, and natural mentoring frameworks used to support youth in education settings. These empirically-supported strategies are parental involvement and mentor training. A conceptual framework that looks at the best practices of mentoring efficacy for transitional-aged youth, designed as a result of this study, will have the greatest and most favorable impact on transitional-aged youth mentees’ needs. Its attributes of attachment theory are supported by lasting psychological connectedness between human beings and their related attachment behaviors/transactions.
ANALISIS STRATEGI PEMASARAN DIGITAL DALAM UPAYA PENINGKATAN OMSET PENJUALAN
Authors: Tyasari Hesti Suryaning , Patrikha Finisica Dwijayati
Published: June 2023

Geprek Bensu merupakan bisnis waralaba yang menawarkan makanan kekinian berupa olahan ayam dengan aneka toping sambal kekinian yang dimiliki salah satu Presenter tanah air yakni Ruben Onsu. Geprek Bensu mulai dikenal masyarakat luas mulai pada awal tahun 2017, hal ini tak luput dengan strategi pemasaran yang dipakai pemilik dengan menggunakan promosi digital. Dengan adanya branding yang kuat maka brand dapat di kenal oleh masyarakat dengan sangat cepat. Adapun Tujuan dari penelitian ini yakni  untuk menganalisis strategi pemasaran digital yang digunakan Geprek Bensu di kota Surabaya dalam upaya peningkatan omset penjualan Geprek Bensu. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan sampel manajer dan karyawan dari geprek bensu pada area kota surabaya. Adapun teknik pengambilan sampel menggunakan metode observasi dan wawancara yang di kirimkan secara online.  Dari hasil penelitian dapat di simpulkan bahwa geprek bensu melakukan promosi pada platfrom digital ojek online yang cukup berhasil karena besar diskon yang membuat konsumen pecinta pedas lebih tertarik untuk membawa pulang pesanannya.