bluuebunny/crossref_metadata_2025 huggingface dataset:
Determinantes del rendimiento académico de la educación media en Ecuador
Authors: Villarruel-Meythaler Ramiro Efraín , Tapia-Morales Karen Irene , Cárdenas-García Joselyn Katherine
Published: June 2023

En este artículo se analizan los determinantes demográficos, fisiológicos, socioeconómicos, culturales, académicos y psicológicos que inciden en el rendimiento académico de los estudiantes que rindieron el examen Ser Bachiller en el periodo lectivo 2016-2017. Además, se describe el origen, evolución y aplicación de los exámenes psicométricos a nivel nacional e internacional. Para observar el efecto que tienen los mencionados factores en el rendimiento académico, se construye un modelo econométrico de regresión logística que muestra la magnitud y la relación de las principales variables que determinan el rendimiento académico de los estudiantes de Educación Media en Ecuador. En este sentido, se observa que los factores que más inciden en el rendimiento académico de los estudiantes de Educación Media son el costo de la preparación propedéutica previo a rendir el examen Ser Bachiller (11,42% mayor) y la manifestación, por parte del estudiante, de tener una percepción de control interno y responsabilidad personal (10,61% mayor).
Innovación abierta como acelerador de competitividad y resultados empresariales, un estudio bibliométrico
Authors: Morales Ricardo Ernesto , Álvarez Aros Erick L.
Published: June 2023

La competitividad empresarial representa una propuesta de valor  única para el mercado, esto se debe al conjunto de esfuerzos internos, materializados por medio  de recursos, y potencial humano, estando alineados a la estrategia organizacional,  pero esta dinámica no debe ser desligada de los factores del entorno. Por ello el propósito del estudio fue analizar a la innovación abierta y la competitividad  y los recursos empresariales a través de la investigación bibliométrica. Los resultados muestran que el modelo abierto catapulta  los motores de competitividad, así como la estrategia y ventaja competitiva, además evidencian que es una vía proba para la consecución de réditos producto de la innovación,  también que el paradigma a transcendiendo barreras culturales, sociales o económicas,   siendo estudiada desde distintas perspectivas, ampliando la idea seminal con nuevos enfoques,  emergiendo como una propuesta desde la académica,  como herramientas novedosas, a la gestión empresarial, palpándose que la innovación abierta  se ha estudiado predominantemente en países desarrollados, generando  teorías que influyen en los países en desarrollo.
La Economía Circular como eje de desarrollo de los países latinoamericanos
Authors: Da Costa Clayson Cosme
Published: June 2023

El presente artículo tiene como objetivo principal analizar si en la actualidad la Economía Circular puede convertirse en el eje sobre el que pivote el crecimiento económico sostenible de las economías de una región como América Latina y el Caribe. Se parte de la definición de Economía Circular y, con posterioridad, se analiza si los rasgos básicos de ella se cumplen en el conjunto de economías latinoamericanas, analizando algunos casos concretos. Asimismo, se plantean los problemas y retos pendientes de las economías de América Latina y el Caribe en relación con la circularidad y, por último, se extraen conclusiones y se esbozan unas futuras líneas de investigación que puedan resultar de interés a nivel académico y práctico.
La paradoja chavista: modelo de desarrollo, Estado y acción política
Authors: Valdez-Sarabia Magaly
Published: June 2023

Este artículo analiza la correlación entre el modelo de desarrollo y la acción política chavista. Se trata de un aporte al estado de la cuestión en el campo de la economía política que vincula la redistribución de recursos con estrategias políticas de “democratización del petróleo”, propias del Estado benefactor. Se concluye que, en los últimos 20 años, ha surgido la siguiente paradoja: mientras el proyecto bolivariano se financia del extractivismo, emplea políticas compensatorias que, lejos de atender las fallas estructurales de la economía rentista, agudizan la crisis y preparan el terreno para la relación entre actores.
Presentación
Authors: Mendieta Rodrigo
Published: June 2023

Presentacion
Importancia de la participación en el diseño de políticas públicas de rehabilitación social en Ecuador
Authors: Iturralde Durán Carlos Antonio
Published: June 2023

La crisis carcelaria ecuatoriana evidenció la inefectividad de las políticas penitenciarias que permitieron el traspaso progresivo del control de las cárceles hacia grupos delictivos, derivando en la intensificación de la violación de derechos humanos y conllevando a masacres y otros tipos de violencia que, superando los muros de la prisión, se desbordaron hacia la sociedad. Tanto las normativas ecuatorianas e internacionales como los marcos teórico-conceptuales, proponen la inclusión de presos a nivel de representación de control ciudadano como mecanismo de ejercicio de derechos y mejora de intervenciones públicas. El objetivo de este artículo es reflexionar sobre la importancia de crear procesos participativos efectivos en el diseño de políticas públicas relacionadas al sistema de rehabilitación social que incluya la voz de los presos, existiendo resultados en países latinoamericanos como Colombia y Uruguay, siendo la reglamentación de la participación un elemento relevante para evitar la corrupción del sistema.
A BOA-FÉ OBJETIVA COMO CRITÉRIO A PRIORI DE JUSTIÇA E A BOA-FÉ SUBJETIVA COMO CRITÉRIO A POSTERIORI DA JUSTIÇA: O CONCEITO DE JUSTIÇA COMO FUNDAMENTO DA AÇÃO HUMANA
Authors: Scremin Neto Ferdinando , Pagani Lucas Augusto Gaioski , Castilho Ricardo
Published: June 2023

A boa-fé é cláusula geral de direito privado cujos contornos objetivos e subjetivos impactam a interpretação dos negócios jurídicos quanto aos efeitos e consequências esperadas dos comportamentos das partes, a fim de extrair não apenas o correto sentido e alcance das cláusulas contratuais, como também conformar as consequências jurídicas decorrentes de eventual inadimplemento das obrigações assumidas pelas partes. Neste contexto a boa-fé objetiva traduz elemento a priori de análise das justas expectativas de comportamentos adequados perseguidos pelas partes, e a boa-fé subjetiva encontra seu fundamento de existência a posteriori, a partir do conceito de justiça como fundamento da ação humana.
Development of Non Hosted Custom Domain Websites As a Learning Medium to Improve Learning Outcomes
Authors: Rufii
Published: June 2023

Learning media plays an important role in the learning process, especially in concrete courses. The use of easy, dynamic and interesting media can have an effect on students to learn compared to boring conventional learning media so that it is necessary to develop new media that can overcome these problems. The purpose of this study is to determine the feasibility and effectiveness of learning media in the form of non-hosted custom domain websites to improve learning outcomes. This research uses a research and development method with a 5-stage ADDIE development model. In the results of the feasibility test, media experts obtained a score with a percentage of 81.33% with a very decent category, while material experts obtained a score with a percentage of 89.33% with a very decent category. The results of the trial on 25 graduate students obtained a percentage of 92% with a very decent category. The increase in learning outcomes above KKM 75 after using non-hosted custom websites reached 84% from the previous 20% so that it can be concluded that the use of non-hosted custom domain websites on learning media can improve learning outcomes. The new findings in this study are in the form of the use of websites that are usually used paid for education, now it is easier and cheaper to use non-hosted websites that are custom domains using the teacher's own name, so that the use of the teacher's name can increase credibility in the world of education, especially in cyberspace. Keywords: Learning Media, Non hosted Website, Improve Learning Outcome
New records of spiders and harvestmen (Arachnida: Aranei, Opiliones) from Khingansky State Nature Reserve and adjacent territories, Amurskaya oblast, Russia
Authors:   Institute of Systematics and Ecology of Animals, Russian Academy of Science, Siberian Branch,Novosibirsk, Russia, Trilikauskas L.A. ,   Tigireksky State Nature Reserve, Nikitina str. 111, Barnaul, 656049, Russia, Sergeev M.E. ,   Federal Scientific Center of East Asia Terrestrial Biodiversity, Far Eastern Branch, Russian Academy of Sciences, Vladivostok, 690022, Russia
Published: June 2023

An annotated list of spiders (65 species from 48 genera in 17 families) and harvestmen (five species from 5 genera in two families) of the Khingansky Reserve and adjacent territories is given. Two spider species (Cyclosa ginnaga and Diaea gyoja) are new for the fauna of Russia. Twenty six species of spiders and four species of harvestmen are new for the fauna of the Amurskaya Oblast. Thirty seven species of spiders and all harvestmen were recorded from Khingansky Reserve for the first time.
First record of the genus Fillus Navás, 1919 (Neuroptera: Ascalaphidae) from Venezuela
Authors:   Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far East Branch of the Russian Academy of Sciences, Vladivostok, 690022, Russia, Makarkin V.N. , Lastukhin A.A. ,   Chuvash National Academy of Sciences and Arts, 15 Lenin Ave., Cheboksary, Chuvash Republic, 428000, Russia
Published: June 2023

The genus Fillus Navás, 1919 (Ascalaphidae: Ascalaphinae) is recorded for the first time from Venezuela based on a female. This is the northern-most locality of the genus. It is preliminarily assigned to the Brazilian species F. amazonicus Machado et Rafael, 2011.
Caprine Myostatin Gene Polymorphism in Domestic and Wild Goat Breeds in Duhok Province/Kurdistan Region of Iraq Using PCR-RFLP and SNP Markers
Authors: Abbas Awat M. , Jubrael Jaladet M. , Mohammed Ahmed B.
Published: June 2023

In Iraq generally and Kurdistan region specifically, goats are an important resource for meat and milk production. It is well known that Myostatin genes (MSTN) have the essential role in growth and development due to its crucial involvement in muscle growth. The goal of this research was to reveal the polymorphism of MSTN gene in different Capra hircus breeds (native, Shami, Meriz and Kamori goat) and in wild mountain goat (Capra aegagrus) via PCR-RFLP technique and direct seqencing The MSTN (exon 1) polymorphisms were investigated in all breeds, MSTN-Dra I/RFLP revealed three genotypes AA and BB were homozygous and AB was heterozygous. The calculated genotype frequencies were 0.270, 0.368 and 0.362 for AA, BB and AB genotype respectively. The allelic frequency was 0.451 for the A allele and 0.549 for the B allele. The average of the observed heterozygosity was 0.362 and the observed homozygosity was 0.638. The sequence data of MSTN gene of Native and Shami goats revealed 31 SNPs in nonfunctional region. In addition, in exon region there was 1 SNPs in both breed samples which did not change amino acid sequence and its silence mutation.
       In conclusion, the result of PCR-RFLP and SNP experiments obtained in this investigation were evaluated as very useful in genotype analysis of local goat breeds/populations. Thus, DNA polymorphisms in the Myostatin gene could be used as reliable genetic marker in breeding programs in this region.
The role of the private sector in the development of education: trends and challenges
Authors: Лолохоева И.А.
Published: June 2023

В настоящее время частное образование становится все более востребованным в России. Частные вузы предлагают не только традиционные образовательные программы, но и современные инновационные форматы обучения, включая онлайн-курсы и дистанционное обучение. Однако, отрасль частного образования сталкивается с рядом вызовов, которые могут затруднять ее развитие. Частный сектор в России в последние годы стал активнее участвовать в развитии образования. Крупные корпорации, такие как "Газпром", "Роснефть", "Сбербанк" и другие, создали собственные фонды, которые финансируют образовательные проекты в различных регионах страны. Цель данной статьи - рассмотреть роль частного сектора в развитии образования в России, проанализировать тенденции развития частного образования, описать проблемы, с которыми сталкиваются частные вузы, а также предложить возможные пути решения данных проблем. Для достижения этой цели были проведены анализ литературных источников, а также исследования и опыт частных вузов в России. Результаты исследования позволяют сделать выводы о роли частного образования в развитии образования в целом, о тенденциях развития отрасли, а также о вызовах и проблемах, которые могут затруднять ее развитие.

Currently, private education is becoming more and more in demand in Russia. Private universities offer not only traditional educational programs, but also modern innovative learning formats, including online courses and distance learning. However, the private education industry faces a number of challenges that may hinder its development. The private sector in Russia has become more actively involved in the development of education in recent years. Large corporations such as Gazprom, Rosneft, Sberbank and others have created their own funds that finance educational projects in various regions of the country. The purpose of this article is to consider the role of the private sector in the development of education in Russia, to analyze the trends in the development of private education, to describe the problems faced by private universities, as well as to suggest possible solutions to these problems. To achieve this goal, an analysis of literary sources, as well as research and experience of private universities in Russia were carried out. The results of the study allow us to draw conclusions about the role of private education in the development of education in general, about the trends in the development of the industry, as well as about the challenges and problems that may hinder its development.
Analysis of the main provisions of the modeling method for use in the process of developing a professionogram of a modern physical education teacher
Authors: Деминская Л.А.
Published: June 2023

При разработке профессиограммы современного учителя физической культуры необходимо использование метода моделирования, изучение структуры, задач и содержания модели профессиональной подготовки как совокупности функциональных педагогических проектов. Данная научная статья посвящена анализу основных положений метода моделирования с целью применения его в процессе разработки профессиограммы для современного учителя физической культуры. В работе рассматриваются различные подходы к моделированию и описывается применение моделирования в педагогической практике. Далее, в статье освещаются особенности разработки профессиограммы и описываются основные составляющие модели современного учителя физической культуры. В заключении, автор подводит итоги и делает выводы о применимости метода моделирования при создании профессиограммы для учителей физической культуры. Работа является актуальной и практически значимой для специалистов, занимающихся разработкой учебных программ и методик в области физического воспитания и спорта.

When developing a professionogram of a modern physical education teacher, it is necessary to use the modeling method, study the structure, tasks and content of the professional training model as a set of functional pedagogical projects. This scientific article is devoted to the analysis of the main provisions of the modeling method in order to apply it in the process of developing a professionogram for a modern physical education teacher. The paper discusses various approaches to modeling and describes the application of modeling in pedagogical practice. Further, the article highlights the features of the development of a professionogram and describes the main components of the model of a modern physical education teacher. In conclusion, the author summarizes and draws conclusions about the applicability of the modeling method when creating a professionogram for physical education teachers. The work is relevant and practically significant for specialists involved in the development of curricula and methods in the field of physical education and sports.
Forming of moral feelings in older preschool children in conditions of poly-artistic activity
Authors: Цзюнь Л.
Published: June 2023

Обсуждение проблемы нравственного воспитания сподвигло нас на рассмотрение такого аспекта, как формирование нравственных чувств у детей старшего дошкольного возраста. В данной статье были рассмотрены понятия нравственности с разных точек зрения, а также проанализировать суть нравственного воспитания с опорой на нормативно-правовую базу. Ссылаясь на теорию нравственного развития Л. Кольберга, мы определили важные составляющие своей работы и разработали этапы организации образовательного процесса, включающие рассмотрение содержания деятельности и методов ведения процесса формирования нравственных чувств. В процессе рассмотрения темы мы определили, что активизация различных видов творческой деятельности, основанных на природной полихудожественности дошкольника, способна достигнуть цели нравственного воспитания. Потому область, служащая главным полем развития нравственных чувств, мы определили именно полихудожественную деятельность. Формирование нравственных чувств осуществляется поэтапно во взаимодействии дошкольной организации и семьи, и показателем сформированности нравственных чувств будет служить практически-деятельностная направленность ребёнка на трансляцию нравственных ценностей. В конце статьи мы перечислили условия, влияющие на развитие нравственных чувств и обобщена проведённая исследовательская работа по данной теме.

The discussion of the problem of moral education prompted us to consider such an aspect as the formation of moral feelings in older preschool children. In this article, the concepts of morality were considered from different points of view, as well as to analyze the essence of moral education based on the regulatory framework. Referring to the theory of moral development L. We identified the important components of our work and developed the stages of the organization of the educational process, including consideration of the content of activities and methods of conducting the process of forming moral feelings. In the process of considering the topic, we determined that the activation of various types of creative activity based on the natural poly-art of a preschooler is able to achieve the goal of moral education. Therefore, the area that serves as the main field for the development of moral feelings, we have defined precisely poly-artistic activity. The formation of moral feelings is carried out in stages in the interaction of the preschool organization and the family, and the indicator of the formation of moral feelings will be the practical-activity orientation of the child to the translation of moral values. At the end of the article, we listed the conditions affecting the development of moral feelings and summarized the research work on this topic.
Photonic Enhancement in Photoluminescent Metal Halide Perovskite–Photonic Crystal Bead Hybrids
Authors: Lapointe Victoria , Imperiale Christian , Chengadu Sollavi , Pomilio Cristina , Ganesh Meera , Kéna-Cohen Stéphane , Majewski Marek
Published: June 2023

The integration of photonic materials with semiconductor nanocrystals by correlating the photonic stopband and the photoluminescence maximum is expected to afford hybrid materials with enhanced optoelectronic properties. Here, we report two photonic crystal–perovskite nanocrystal microbead hybrids synthesized through simple vacuum drying techniques. Photonic polystyrene microbeads combined with metal halide perovskite (CsPbBr3 and CsPbBr1.5Cl1.5) nanocrystals yield hybrids with photoluminescence matching that of the parent nanocrystals and increased photoluminescence quantum yields. Time-resolved photoluminescence spectroscopy quantifies the radiative enhancement afforded by the photonic environment of the microbeads. These nanocrystal–microbead hybrids also demonstrate markedly better resistance to degradation in water over 30 days of immersion compared to their colloidal counterparts.
Boundary Conditions for Promotion versus Poisoning in Copper-Gallium-based CO2–to–Methanol Hydrogenation Catalysts
Authors: Alfke Jan L. , Tejeda-Serrano Maria , Gani Terry Z. H. , Rochlitz Lukas , Zhang Seraphine B. X. Y. , Lin Lin , Copéret Christophe , Safonova Olga V.
Published: June 2023

To establish descriptors for the activity of Cu-Ga-based CO2-to-methanol hydrogenation catalysts, we prepared via co-grafting followed by a reduction in hydrogen, a series of materials containing 3-6 nm Cu1-xGax alloyed nanoparticles with variable xGa. They display a volcano-type activity behavior, where methanol formation is promoted for xGa < 0.13, while above poisoning effects are observed. In catalysts that are prepared via different methods and differ in the degree of Ga reduction, only the fraction of Ga0 in the formed Cu-Ga alloy matters for the catalytic activity. We were therefore able to establish that the concentration of Ga0 in the Cu-Ga alloyed precatalyst is the main descriptor of methanol formation activity.
Electric Field Susceptibility of Chlorophyll c and its Effect on the Excitation Energy Ladder in the Major Light-Harvesting Complex of Diatoms
Authors: Maity Sayan , Daskalakis Vangelis , Kleinekathöfer Ulrich
Published: June 2023

Diatoms are one of the most abundant photosynthetic organisms on earth and contribute largely to the atmospheric oxygen production. They contain fucoxanthin and chlorophyll-a/c binding proteins (FCPs) as light-harvesting complexes with a remarkable adaptation to the fluctuating light on ocean surfaces. To understand the basis of the photosynthetic process in diatoms, the excitation energy funneling within FCPs needs to be probed. A state-of-the-art multiscale analysis within a quantum mechanics/molecular mechanics framework has been employed. To this end, the chlorophyll (Chl) excitation energies within the FCP complex from the diatom Phaeodactylum tricornutum have been determined. The Chl-c excitation energies were found to be significantly lower than those in organic solvents. This finding challenges the general belief that the excitation energy of Chl-c is higher than that of Chl-a in FCP proteins and reveals that Chl-c molecules are much more sensitive to electric fields within protein scaffolds than Chl-a pigments. A direct connection to experiment is obtained by analysis of the linear absorption spectrum of FCP.
Cancer alertness as a basis for timely diagnosis and effectiveness of therapy: A review
Authors: Volkova Anastasiya S. , Belysheva Tatiana S. , Mikhaylova Svetlana N. , Ryabukhina Yulia E. , Zeynalova Pervin A.
Published: June 2023

Early diagnosis of malignant neoplasms in children is an important and relevant task. Despite the growth of actively diagnosed malignant neoplasms, the proportion of cases of the disease at stage III or IV remains high. In the structure of pediatric mortality, malignant neoplasms occupy a significant fraction, which marks the need for a thorough diagnostic search and, in turn, early detection of cancer. For patients who have completed treatment for a malignant neoplasm, active observation regarding the occurrence of a relapse or the appearance of second tumors remains relevant. Detection of malignant neoplasms in the early stages is possible with an appropriate level of cancer alertness, a multidisciplinary approach to the diagnosis and treatment of this rare group of diseases.
Maternal-fetal attachment as a natural phenomenon of pregnancy and maternity development: A review
Authors: Kelmanson Igor A.
Published: June 2023

Pregnancy is the most important stage in the formation of motherhood, maternal programming. An integral component of this process is maternal-fetal attachment, which can be defined as the bonds between a woman and a fetus that depend on the cognitive and emotional abilities to perceive another human being and include thoughts, behavior, emotions and relationships. The formation of maternal-fetal attachment is presumably due to the high plasticity of the brain of a pregnant woman, which results in significant structural and functional changes in its individual structures. The study of maternal-fetal attachment is possible using standardized questionnaires, one of which is the Maternal Antenatal Attachment Scale. The paper provides the Russian version of this questionnaire and its reference values. Maternal-fetal attachment depends on the personality characteristics of the woman and, to a lesser extent, on socio-demographic factors, and its characteristics have a prognostic value for the psychological and somatic health of the mother and child. Assessment of maternal-fetal attachment and its optimization should be considered as an integral component of medical and psychological support for pregnant women.
Incidence of the new coronavirus infection in children based on outpatient data in Voronezh
Authors: Cherkasova Olga A. , Moshurova Larisa V.
Published: June 2023

Background. The article analyzes the COVID-19 incidence in children managed in the pediatric outpatient department of the Voronezh City Outpatient Clinic №1, summarizes and systematizes the data on the spread of SARS-CoV-2 in children.
Aim. To study the COVID-19 incidence in the children of the pediatric outpatient department №2 of the Voronezh City Outpatient Clinic №1 by age group and gender for 20202022.
Materials and methods. A retrospective epidemiological analysis was carried out at of the pediatric outpatient department №2 of the Voronezh City Outpatient Clinic №1. The incidence of COVID-19 in children in 20202022 was studied on the basis of information from the register of infectious diseases (form 060/y). The study included all laboratory-confirmed cases of COVID-19 infection in children registered in the Voronezh City Outpatient Clinic №1 for 20202022. Patients were divided into groups by age and gender to study the features of the course of the new coronavirus infection.
Results. There were no gender differences in the structure of COVID-19 incidence in 20202022, according to the data of the pediatric outpatient department №2 of the Voronezh City Outpatient Clinic №1. COVID-19 was reported in all age groups; the lowest rate was in newborns (0.3%), the highest in children 1014 years old (25.7%).
Conclusion. Six completed epidemic waves were observed in the study period, corresponding to all-Russian statistical data. There were no deaths reported in healthcare organizations for the study period.
Key issues in selecting an antibacterial drug for the treatment of acute respiratory infections in children: A review
Authors: Zaytseva Svetlana V. , Lokshina Evelina E. , Zaytseva Olga V.
Published: June 2023

Аcute respiratory diseases in children remain an urgent problem in pediatric practice. Most respiratory infections are due to viruses, but some may be due to bacterial pathogens or associations. During the pandemic of a coronavirus infection the number of unjustified prescriptions of antibiotics increased, which significantly complicated the situation with drug resistance of microorganisms and changed the strategy for choosing a starting antibacterial drug in children. Under the current circumstances, timely diagnosis of bacterial inflammation and the adequate choice of drug are the key issues in the practice of a pediatrician. On an outpatient basis it is important for a pediatrician to determine the indications timely and empirically prescribe an effective antibacterial drug. In Russia, in recent years, Federal Clinical Guidelines for various nosologies have been approved, defining indications for systemic antibiotic therapy. According to clinical guidelines, amoxicillin is the first-line antibiotic for most bacterial acute respiratory infections. In addition, there are cohorts of children who are expected to have risk factor as drug-resistant organisms and these children are eligible for protected amoxicillin as a first-line medication. The indications for prescribing macrolides and third-generation oral cephalosporins have fundamentally changed. The article presents the defining indications for systemic antibiotic therapy and the features of the choice of the starting antibacterial drug in children with acute respiratory infections.
Missense variant interaction scanning reveals a critical role of the FERM domain for tumor suppressor protein NF2 conformation and function
Authors: Moesslacher Christina S , Auernig Elisabeth , Woodsmith Jonathan , Feichtner Andreas , Jany-Luig Evelyne , Jehle Stefanie , Worseck Josephine M , Heine Christian L , Stefan Eduard , Stelzl Ulrich
Published: June 2023

NF2 (moesin–ezrin–radixin-like [MERLIN] tumor suppressor) is frequently inactivated in cancer, where its NF2 tumor suppressor functionality is tightly coupled to protein conformation. How NF2 conformation is regulated and how NF2 conformation influences tumor suppressor activity is a largely open question. Here, we systematically characterized three NF2 conformation-dependent protein interactions utilizing deep mutational scanning interaction perturbation analyses. We identified two regions in NF2 with clustered mutations which affected conformation-dependent protein interactions. NF2 variants in the F2–F3 subdomain and the α3H helix region substantially modulated NF2 conformation and homomerization. Mutations in the F2–F3 subdomain altered proliferation in three cell lines and matched patterns of disease mutations in NF2 related-schwannomatosis. This study highlights the power of systematic mutational interaction perturbation analysis to identify missense variants impacting NF2 conformation and provides insight into NF2 tumor suppressor function.
Transformasi UMKM Melalui Strategi Digitalisasi Marketing Guna Meningkatkan Ekonomi Kreativ Desa Sengon Kabupaten Jombang
Authors: Rachyu Purbowati  , Bagas Maulana Pasha Aditya Prada
Published: June 2023

The SRI IBU herbal medicine MSME located in RT32/RW02, Sengon Village, Sengon Krajan, Jombang has a fairly good background in business activities. This product is marketed in liquid form and lasts only one week, so the marketing process must be immediate and a matter that requires attention. In addition, the herbal medicine production business is still managed traditionally without good business management and business planning. Even though it is done traditionally, its production has expanded to sub-districts and cities. However, the distribution permit for the product and its quality have not been tested, so this herbal medicine can only be marketed through private orders. So far there has been no real effort to fulfill the wishes of the local people in the target locations. Even though it requires direct information about how to utilize this based herbal medicine, community service is carried out through Digital Marketing education (socialization) and SRI IBU herbal medicine development training. The purpose of this activity is to provide knowledge and efforts to improve products and their marketing. The processing of various medicinal plants into herbal medicine provides an opportunity for added value so that it is possible to have an economic impact if it is marketed seriously by the target community.

 

Keywords: Digital Marketing, MSMEs, Sengon.
MEAT PRODUCTIVITY OF YOUNG ROMANOV SHEEP AND CROSSBREEDS (¼ ROMANOV × ¾ ILE DE FRANCE)
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, DVALISHVILI V.G.
Published: June 2023

The study of the slaughter indicators of Romanov rams and crossbred sheep (¼ Romanov × ¾ Ile de France) showed that the crossbreeds signifi cantly surpass Romanov peers in all slaughter indicators.
MORPHOLOGICAL COMPOSITION AND TISSUE RATIO IN THE CARCASS OF ROMANOV BREED SHEEP AND ITS CROSSBREEDS WITH THE EDILBAEV BREED
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, KOSILOV V.I.
Published: June 2023

The article presents the results of crossing Romanov sheep with Edilbaev sheep in the production of young mutton. It was found that due to the eff ect of crossing, the crossbreeds of the fi rst generation (½ Romanovskaya × ½ edilbai) and the second generation (¼ Romanovskaya × ¾ edilbai) were distinguished by a higher yield of the edible part of the carcass, the meat content coeffi cient, the yield of carcass pulp per 1 kg of pre-slaughter live weight, a better ratio of edible and inedible parts and a muscle-fat ratio in compared with purebred youngsters of the Romanov breed.
Hadis Terbitnya Bintang Ṡurayyā Dalam Musnad Imam Ahmad Bin Hanbal (Studi Sanad Dan Matan Hadis)
Authors: Hurairah Abi
Published: June 2023

Berawal dari wabah virus Covid-19 yang tak kunjung sirna, menjadikan sebagianbesar pihak merasakan penderitaan. Hingga wajar jika semua golongan sangatberharap wabah ini segera hilang. Sebagaimana kehebohan berita yang beredarmelalui akun twitter milik salah seorang warga yang beragumen bahwa wabah covid19 ini akan segera berakhir apabila telah terbit sebuah bintang di waktu pagi. Haltersebut berlandaskan keterangan dari hadis Nabi صلى الله عليه وسلم dalam riwayat Imam Ahmad binHanbal yang menyatakan hal demikian. Namun pada kenyataannya hingga saat iniwabah Covid-19 itu masih ada. Adanya kejadian tersebut dikhawatirkan menimbulkandugaan di kalangan masyarakat bahwa tidak semua ucapan nabi benar (bohong).dengan hal ini maka peneliti memfokuskan dua rumusan masalah. Pertama,bagaimana kualitas sanad dan matan hadis tentang terbitnya bintang Ṡurayya sebagaitanda berakhirnya wabah, kedua Bagaimana kandungan isi hadis tersebut. Penelitianini menggunakan metode takhrij wa dirāsah al-asanid pada sanad, sedangkan padamatan menggunakan metode Syarhu al-Hadīṡ. Adapun pendekatan yang digunakanadalah historis dengan jenis penelitian library reseach. Adapun metode pengumpulandata yang digunakan adalah takhrij, iʻtibar dan Syarhu al-ḥadīṡ. Hasil dari penelitianini menyimpulkan bahwa hadis tentang terbitnya bintang Ṡurayya dalam musnadImam Ahmad tergolong Ḥasan Garib. Jika dilihat sanadnya, hadis ini tergolongmuttaṣil. Namun secara kualitas, hadis ini dinilai ḥasan karena ada perawi yangkredibilitasnya tidak memenuhi syarat hadis ṣaḥīḥ yakni ʻIsl bin Sufyān al-Tamīmī alYarbūʻī, beliau dinilai ḍaʻīf. Karena hanya bersumber dari sahabat Abū Hurairah dankemudian hanya berporos kepada Imam Ahmad bin Hanbal, maka hadis ini dinilaigarīb dan termasuk garīb mutlaq. Sedangkan matannya tidak Ṣaḥīḥ karena tidakmencukupi kriteria ke-ṣaḥīḥ-an matan. kekurangan tersebut, yakni bertentangandengan dalil Al-Qur’an dan akal sehat. Adapun isi kandungan hadis ini adalahpenjelasan atau informasi Nabi صلى الله عليه وسلم terkait waktu hilangnya hama yang ditandai denganterbitnya bintang (Ṡurayyā) pada waktu pagi. Namun yang harus digaris bahawahiadalah kata al-ʻĀhatu di sini bukan wabah Covid-19 (corona) atau wabah padaumumnya, melainkan perselisihan dan sengketa di antara orang-orang arab pada masaitu terhadap jual beli buah-buahan yang cacat atau rusak karena belum waktunyauntuk di panen. Oleh Nabi kemudian melarang kegiatan tersebut dan menjadikanterbitnya bintang Ṡurayya sebagai tolak ukur diperbolehkannya kembali jual beli. Haltersebut dikarenakan pada saat bintang Ṡurayya terbit, menurut kebiasaan di tanahhijaz merupakan awal musim panen tiba yang pada akhirnya menjadikan perselisihanjual beli tersebut terhindarkan (hilang/diangkat).
Meneropong Upaya Qur’anisasi Masyarakat Kampung di Ujung Timur Pulau Jawa (Studi Living Qur’an)
Authors: Lestari Puput
Published: June 2023

Artikel ini merupakan sebuah observasi yang penulis lakukan ketika berada diBanyuwangi. Banyuwangi yang dalam sejarah merupakan kota yang dulunyamayoritas beragama Hindu, sekarang kota tersebut berubah menjadi kota mayoritasmuslim dan religius. Penelitian ini menitikberatkan pada pengamatan terhadapkebiasaan membaca Alquran di lingkungan masyarakat salah satu kampung diBanyuwangi. Beberapa pengamatan dilakukan di bulan Ramadan, dan beberapadilakukan di luar bulan Ramadan. Kemudian dalam mengambil data, penulis melakukan wawancara kepada salah satu guru ngaji setempat dan beberapa daripengamatan yang dilakukan oleh penulis ketika ikut berpartisipasi dalam beberapakegiatan tersebut. Dari hasil penelitian dan observasi yang dilakukan penulis,ternyata ada sisi yang menarik yang menampilkan kesalehan warga kampungtersebut. Di antaranya, aplikasi pengamalan nilai-nilai Alquran melalui pembacaanAlquran yang beragam bentuk dan dianggap sebagai jantung dalam menunaikanibadah. Bentuk pembacaan Alquran yang beragam itu dimulai dari kegiatanmembaca Alquran di bulan Ramadan yang dipadukan dengan tradisi budaya lokalsetempat, dan beberapa majelis-majelis sima’an Alquran yang didirikan secarakolektif yang memiliki nuansa yang unik dan khas.
Application of compost tea, co-inoculation and inorganic fertilization on Swiss chard plants
Authors: Rodríguez-de la Garza José Antonio , Guerra-Guerra Claudia Nayeli , Trejo-Téllez Libia Iris , Alvarado-Camarillo Daniela , González-Méndez Laura María , Méndez-López Alonso , Martínez-Amador Silvia Yudith
Published: June 2023

Swiss chard is a horticultural crop with a highly nutritious value. These crops’ production required nutrients, which can be provided through mineral nutrient solutions or biofertilizers. Biofertilizers are products that contain beneficial microorganisms that improve soil quality and that promote plant growth. Additionally, these microorganisms carry out nitrogen fixation and phosphate solubilization. The present work assessed the application of compost tea, co-inoculation (Azospirillum and Glomus), and inorganic fertilizer over the growth (roots, stem, and leaves) and nutrient content in Swiss chard (Beta vulgaris var. Forhook Giant) plants. The present work was carried out in a greenhouse using a randomized complete block design. Swiss chard plants treated with compost tea + inorganic fertilization (CTIF) accumulated more root and stem dry weight (4.06 and 8.10 g respectively), and, on the other hand, the leaf dry weight increased under three treatments: inorganic fertilization (IF), compost tea + co-inoculation (CTCi) and CTIF (12.5, 9.22 and 10.5 g respectively). Leaf area was greater in the IF and CTIF treatments. In Control (C) P and Mg content were higher; CTCi treatment increased the N, K, and Mn content; the co-inoculation (Ci) treatment increased Cu content as well as CTIF treatment increased the Ca, Fe, Zn, and B contents and in a lesser extent also the P, Mg, Cu, and Mn contents. The biomass partitioning coef ficient indicates that in six samples (from a total of seven samples), most of the photosynthates (PS) were used by the plants to form new leaves or to increase the size of the leaves. If an alternative method of fertilization is desired, it is recommended that a combination of biofertilizer and inorganic fertilization should be used, such as, the combination of compost tea and mineral solution that increased the production and the concentration of nutrients in the Swiss chard crop.
Estructura poblacional y fenología de cuachalalate (Amphipterygium adstringens) desarrollado sobre litosol degradado en la costa de Oaxaca
Authors: Ortega-Baranda Verónica , De la Cruz-Salinas Deysi Lizeth , Romero-Manzanares Angélica , Sánchez-Bernal Edgar Iván
Published: June 2023

Amphypterigium adstringens “cuachalalate” crece en los suelos degradados de la selva baja de la costa de Oaxaca. Dos objetivos fueron llevados a cabo: 1. En cuachalalate: obtener la estructura poblacional vertical y horizontal, identificar el patrón de dispersión de los individuos y observar el periodo de las fases fenológicas. 2. En el suelo: determinar las características físicas y químicas del litosol degradado de San Pedro Mixtepec, Oaxaca, donde crece el cuachalalate. En sitios de 1000 m2 fueron registrados todos los individuos de cuachalalate. Éstos fueron clasificados por etapas de crecimiento (brinzal, latizal, fustal). Para analizar la jerarquía de tamaños de las poblaciones de cuachalalate se analizó la estructura horizontal y vertical. La dispersión espacial de las poblaciones fue estimada con el índice de Morisita. En los fustales se registraron los eventos fenológicos: foliación, floración femenina y masculina, fructificación y defoliación, durante un año (época lluviosa de 2017 a época seca de 2018). La estructura vertical de las poblaciones de cuachalalate presentó dos estratos: inferior (2.0 a 9.5 m) y superior (10.0 a 16.0 m); la estructura horizontal mostró que brinzales y latizales tienen diámetros < 2.5 cm y fustales de 5 a 10 cm. La distribución espacial de las poblaciones es agregada. La floración ocurrió durante la época lluviosa, la fructificación durante la época lluviosa a la seca del siguiente año, la foliación de la época seca a la lluviosa del mismo año, la defoliación de la época lluviosa a la seca del siguiente año. Los litosol degradados tienden a ser erosionados por escurrimiento, son impermeables e hidrófobos. Los suelos de piedemonte poseen características físicas y químicas que destacan procesos incipientes de acumulación, lo que anticipa transición hacia regosol éutrico, suelo favorable para la persistencia de la selva baja caducifolia.
Quelites usados en alimentación avícola
Authors: Camacho-Escobar Marco Antonio , Jerez-Salas Martha Patrícia , López-Garrido Serafín Jacobo , Galicia-Jiménez Mónica Marcela , Ávila-Serrano Narciso Ysac , Sánchez-Bernal Edgar Iván
Published: June 2023

En la avicultura tradicional el consumo de plantas frescas es parte importante de la alimentación y componente fundamental de la técnica indígena de crianza avícola. Por ello, el objetivo es conocer los estudios que han incluido algún quelite para la alimentación de aves domésticas. Quelite es un término usado para denominar a las plantas tiernas comestibles los cuales son aprovechados como planta entera, rebrotes, ramas, hojas, peciolos, tallos o flores. En la presente revisión se considerarán los quelites Amaranto (Amarantus sp.), Chepil (Crotalaria longirostrada), Epazote (Dysphania ambrosioides), Hierba mora (Solanum americanum), Hierba santa (Piper autitum), Guaje (Leucaena leucocephala), Huazontle (Chenopodium berlandieri subesp. nuttalliae) y Verdolaga (Portuca olerecea). Se presentan características nutricionales y nutracéuticas de dichos quelites. En pruebas de producción de huevo y carne, tanto en gallinas como en guajolotes nativos, se presentan los principales resultados de dichos estudios. El uso de quelites en la avicultura ha comenzado a probarse con la finalidad de reducir los costos de producción, sin afectar las variables productivas ni la calidad de huevo o carne. A pesar que se ha reportado información contradictoria, existe suficiente evidencia para continuar esta línea de estudio. Está probado que los quelites tienen diferentes propiedades nutricionales y nutracéuticas, las cuales se pretenden aprovechar en favor de los productores y los consumidores; sin embargo, falta mucha investigación al respecto.
Green Concept of Kulon Progo Airport Development Using UMI Simulation
Authors: Mulyani Sri , Rianto Rianto , Adiputra Bangga Dirgantara
Published: June 2023

High energy consumption on the airport becomes a very crucial issue nowadays. Uninterruptable energy supply is required to support airline’s activity and keep the passenger convenience. Regarding the mentioned problem, there is a need to enhance the current plan of the airport with green airport concept. Green airport concept also known as eco-airport is an airport that adopted green and sustainable ecosystem concept to integrate community and environment that lead to reduction of energy consumption. The blueprint of Kulon Progo airport with green concept located in D.I. Yogyakarta, Indonesia has been made and the construction will be start in the mid of 2016. The airport has a FAR of 0.16 with 637 hectares land area. This study is simulating the plan to assess the energy consumption and CO2 emission in each part of the building in Kulon Progo Airport by using Urban Modeling Interface  simulator. From the results, it can be seen that the passenger terminal building is responsible for the highest share with 1,351,861.01 Kwh while second floor of ATC building has the highest CO2 emission 2,679.77 kgCO2/m
Review of three historical collections of fossils of Cenozoic vertebrates from the province of Leon (Spain
Authors: Fidalgo-Casares Darío , Fernández-Martínez Esperanza , Celis Sánchez Jesús
Published: June 2023

This work aims to document three historical paleontological collections of Cenozoic vertebrate fossils from the Leon province. Specifically, those published by Gómez de Salazar (1850), Gago Rabanal (1910) and Royo y Gómez (1930). After decades of being lost, the first two have been found in two different institutions of the city of León. A provisional intervention on the specimens of these collections has been carried out, including cleaning and consolidation, as well as a preliminary anatomical and taxonomic determination, and a proper cataloguing that contains all the available information. The third collection is housed in the Museo Geominero with replicas in the Museo Nacional de Ciencias Naturales (Madrid). The review of these specimens has provided data on the occurrence of new or rare taxa and fossil elements of the fossil record of Neogene vertebrates in the province of Leon, and has extended the knowledge of previous palaeontological work in the area of study. These results imply the revaluation and care of material with scientific and historical value, that should be housed in institutions where they can be adequately keeped. Este trabajo tiene por objetivo documentar tres colecciones paleontológicas históricas de fósiles de vertebrados del Cenozoico de León. En concreto las publicadas por Gómez de Salazar (1850), Gago Rabanal (1910) y Royo y Gómez (1930). Las dos primeras han sido halladas, tras décadas de estar perdidas, en sendas instituciones de la ciudad de León. Sobre estas colecciones se ha realizado la intervención provisional de las piezas que incluye limpieza y consolidación, así como una determinación anatómica y taxonómica preliminar, y una correcta catalogación que contiene toda la información disponible. La tercera colección se encuentra depositada en el Museo Geominero con réplicas en el Museo Nacional de Ciencias Naturales (Madrid). La revisión de estos ejemplares ha aportado datos sobre la presencia de taxones y elementos fósiles nuevos o escasos para el registro fósil de vertebrados del Neógeno de la provincia de León y ha ampliado el conocimiento de los trabajos paleontológicos previos en el área de estudio. Estos resultados suponen la revalorización y cuidado de materiales con valor científico e histórico, los cuales deberían ser depositados en instituciones donde puedan ser adecuadamente custodiados