bluuebunny/crossref_metadata_2025 huggingface dataset:
Theoretical study on the interactions of halogen‐bonds and pnicogen‐bonds in phosphine derivatives with Br2, BrCl, and BrF
Authors: Jiao Yinchun , Liu Yi , Zhao Wenjing , Wang Zhaoxu , Ding Xunlei , Liu Hexiu , Lu Tian
Published: July 2017

The MP2 ab initio quantum chemistry methods were utilized to study the halogen‐bond and pnicogen‐bond system formed between PH2X (X = Br, CH3, OH, CN, NO2, CF3) and BrY (Y = Br, Cl, F). Calculated results show that all substituent can form halogen‐bond complexes while part substituent can form pnicogen‐bond complexes. Traditional, chlorine‐shared and ion‐pair halogen‐bonds complexes have been found with the different substituent X and Y. The halogen‐bonds are stronger than the related pnicogen‐bonds. For halogen‐bonds, strongly electronegative substituents which are connected to the Lewis acid can strengthen the bonds and significantly influenced the structures and properties of the compounds. In contrast, the substituents which connected to the Lewis bases can produce opposite effects. The interaction energies of halogen‐bonds are 2.56 to 32.06 kcal·mol−1; The strongest halogen‐bond was found in the complex of PH2OH•••BrF. The interaction energies of pnicogen‐bonds are in the range 1.20 to 2.28 kcal·mol−1; the strongest pnicogen‐bond was found in PH2Br•••Br2 complex. The charge transfer of lp(P) σ*(BrY), lp(F) σ*(BrP), and lp(Br) σ*(XP) play important roles in the formation of the halogen‐bonds and pnicogen‐bonds, which lead to polarization of the monomers. The polarization caused by the halogen‐bond is more obvious than that by the pnicogen‐bond, resulting in that some halogen‐bonds having little covalent character. The symmetry adapted perturbation theory (SAPT) energy decomposition analysis showes that the halogen‐bond and pnicogen‐bond interactions are predominantly electrostatic and dispersion, respectively.
Inhibition of Protein Synthesis with Highly Soluble Caged Compounds
Authors: Marter Kathrin , Wetzel Janina , Eichhorst Jenny , Eremina Nadja , Leboulle Gérard , Barth Andreas , Wiesner Burkhard , Eisenhardt Dorothea
Published: July 2017

To target protein synthesis in defined areas, e. g. neuropiles of small brains or subcellular structures, locally restricted inhibition of protein synthesis is needed and can be realized by caged compounds of protein synthesis inhibitors (PSI). Since organic solvents interfere with protein synthesis themselves, the use of water‐soluble caged PSIs is a prerequisite in studies on protein synthesis. Such compounds are sparsely available. We developed and characterized efficient highly soluble caged compounds of the PSIs anisomycin and emetine masking their biological activity with a {8‐[bis(carboxymethyl)aminomethyl]‐6‐bromo‐7‐hydroxycoumarin‐4‐yl}methoxycarbonyl (BBHCMOC) derivative. The absorption spectra of the resulting BBHCMOC‐caged anisomycin and BBHCMOC‐caged emetine show long‐wavelength maxima and the extinction coefficients are high, allowing uncaging under non‐damaging light conditions. When uncaged, these caged PSIs reliably inhibit protein synthesis in an in vitro translation system and in cell culture. Taken the whole spectrum of properties into account, our BBHCMOC‐caged PSIs are highly qualified for in vivo studies.
Disentangling the effects of predation and oceanographic fluctuations in the mortality of two allopatric seabird populations
Authors: Matović Nikola , Cadiou Bernard , Oro Daniel , Sanz‐Aguilar Ana
Published: July 2017

Life‐history traits of migratory seabirds are influenced by changing conditions at breeding and wintering grounds. Climatic conditions and predation are known to impact populations’ survival rates, but few studies examine their effect simultaneously. We used multievent capture–recapture models to assess mortality due to environmental conditions and predation in breeding European storm petrels (Hydrobates pelagicus) in two allopatric colonies (Mediterranean and Atlantic). Predatory mortality at the colonies showed annual variation, being around 0.05 in certain years. Mortality at sea differed between the two oceanic basins, and was lower in the Mediterranean colony [0.11, 95% CI (0.09, 0.14)] when compared to the Atlantic colony [0.18, 95% CI (0.15, 0.22)]. The Western Mediterranean Oscillation index (WeMOi) explained 57% of the temporal variability in mortality of Mediterranean breeders. In comparison, 43% of the temporal variability in mortality of Atlantic breeders was explained by the winter St Helena index (wHIX) and El Niño‐Southern Oscillation index (wENSO). Our results suggest that Mediterranean breeders remain in this basin for wintering where they may face lower migratory costs and more favourable environmental conditions. In contrast, Atlantic breeders’ mortality may be due to higher cost of migration, changing upwelling conditions in the Benguela current and heavy storms over their migratory route during La Niña events. This study underlines the importance of modelling separately different causes of mortality when testing the effects of climatic covariates.
Differential Scanning Calorimetry (DSC) and Thermodynamic Prediction of Liquid Fraction vs Temperature for Two High-Performance Alloys for Semi-Solid Processing (Al-Si-Cu-Mg (319s) and Al-Cu-Ag (201))
Authors: Zhang Duyao , Atkinson Helen V. , Dong Hongbiao , Zhu Qiang
Published: July 2017

There is a need to extend the application of semi-solid processing (SSP) to higher performance alloys such as 319s (Al-Si-Cu-Mg) and 201 (Al-Cu-Ag). The melting of these two alloys was investigated using differential scanning calorimetry (DSC) and thermodynamic prediction. The alloys had been processed by magneto-hydrodynamic (MHD) stirring before receipt to produce a microstructure suitable for SSP. The DSC results for the as-received MHD material were compared with those for material which has been taken through a complete DSC cycle and then reheated for a second DSC run. The effects of microsegregation were then analyzed. A higher liquid fraction for a particular temperature is found in the second DSC run than the first. Microstructural observations suggest this is because the intermetallics which form during the first cooling cycle tend to co-located. Quaternary and ternary reactions then occur during the second DSC heat and the co-location leads to enhanced peaks. The calculated liquid fraction is lower with 10 K/min DSC heating rate comparing with 3 K/min at a given temperature. The DSC scan rate must therefore be carefully considered if it is to be used to identify temperature parameters or the suitability of alloys for SSP. In addition, the starting material for DSC must represent the starting material for the SSP. With thermodynamic prediction, the equilibrium condition will provide better guidance for the thixoforming of MHD stirred starting material than the Scheil condition. The Scheil mode approximates more closely with a strongly microsegregated state.
Phospholipid Profiles of Oleaginous Pressed Cakes Using NMR and Gas Chromatography
Authors: Cansell Maud , Bardeau Tiphaine , Morvan Estelle , Grélard Axelle , Buré Corinne , Subra‐Paternault Pascale
Published: July 2017

Camelina, flaxseed, hemp, sesame, and walnut cakes were analyzed for their phospholipid (PL) content and composition using 31P and 1H nuclear magnetic resonance and gas chromatography. The data evidenced variations between the sources in terms of (1) total lipid content and PL concentration, camelina cake being the richest source of PLs, (2) PL composition, phosphatidylcholine being the most abundant phospholipid in sesame and hemp cakes, whereas phosphatidylinositol represented about 25% of the total PLs in most cakes, and (3) fatty acid composition of the PLs, camelina cake being the richest source of omega 3 polyunsaturated fatty acids. These data may be useful to diversify the PL sources available and to provide PL fractions with specific nutritional or functional properties.
Enzymatic Production of Highly Unsaturated Monoacyglycerols and Diacylglycerols and Their Emulsifying Effects on the Storage Stability of a Palm Oil Based Shortening System
Authors: Zhang Zhen , Ma Xiang , Huang Huihua , Li Guanghui , Wang Yong
Published: July 2017

MDs [monoacylglycerols (MAGs) and diacylglycerols (DAGs) mixture] are widely‐used emulsifiers in specialty fats industrial production. An enzymatic production of highly unsaturated MDs (HUSMDs) and its effects on the storage stability of a palm oil‐based shortening system are reported. Oleic acid and corn oil were used to produce HUSMDs in a bubble column reactor (BCR) system in the presence of Novozyme 435. Under the optimized reaction conditions, the content of HUSMDs in the products was above 82 wt% with 46.67 wt% of MAGs and 35.56 wt% DAGs, respectively. Moreover, in the subsequent evaluation of MDs’ effects on the storage stabilities of a palm oil‐based shortening system (IEPO), HUSMDs proved to be a potent emulsifier with decent aeration properties and a possible alternative to saturated MAGs and DAGs (SMDs) made from fully hydrogenated high erucic acid colza oil. Compared with SMDs, HUSMDs decreased the crystallization rate significantly. The microstructure of them shows improved stability of β′ crystals, and no obvious aggregation of crystals was recorded in IEPO with HUSMDs, which also demonstrated the most stable hardness.
BEEF CATTLE RETAINED OWNERSHIP AND PROFITABILITY IN TENNESSEE
Authors: TANG MINFENG , LEWIS KAREN E. , LAMBERT DAYTON M. , GRIFFITH ANDREW P. , BOYER CHRISTOPHER N.
Published: July 2017

The effect of animal characteristics and placement decisions on retained ownership profitability of Tennessee cattle from 2005 to 2015 was determined using a mixed model regression. Ex post simulation analysis examined retained ownership profitability by placement season under different animal characteristic and corn price scenarios. Regression results indicate that placement weight, placement season, days on feed, animal health, and animal sex affect retained ownership profitability. Simulation results indicate that winter placement of cattle in feedlots had the highest expected retained ownership profits. Results provide risk-averse producers information regarding the profitability of retained ownership.
Rescue extracorporeal membrane oxygenation therapy in methamphetamine toxicity
Authors: Morrison Laura K. , Kromm J , Gaudet J , Zuege D , Button B , Warshawski F , Lucyk SN
Published: July 2017

Complications related to methamphetamine use and abuse are common presentations seen in the emergency department. Standard management focuses on addressing the central nervous system and cardiovascular effects with the use of sedation and hemodynamic support. We describe a case report of a patient with methamphetamine toxicity and subsequent severe cardiomyopathy refractory to conventional management that responded to cardiovascular support with extracorporeal membrane oxygenation therapy (ECMO). A 22-year-old female was admitted in severe cardiogenic shock following intravenous administration of methamphetamine and oral fentanyl use. Despite aggressive treatment with benzodiazepines, intravenous fluids, vasopressors, vasodilators, antibiotics and inotropes, the patient’s clinical status deteriorated, and she suffered a cardiac arrest. The patient was successfully resuscitated, and following the return of spontaneous circulation, ECMO was initiated. After 82 hours the patient was successfully weaned from ECMO with the recovery of her left ventricular function and no neurologic sequelae. The patient developed leg ischemia requiring embolectomy and open repair as a complication of ECMO cannulation. In our case, ECMO was used successfully in treating severe cardiac dysfunction from acute methamphetamine-induced cardiomyopathy and was used as a bridge to recovery. The complications seen in this patient emphasize the potential risks associated with this intervention and highlight the need for careful patient selection.
The Ongoing Syrian Arab Republic Health Care Crisis
Authors: Phillips Steven J.
Published: July 2017

Prior to the Syrian civil war, access and delivery of health care and health care information over the past 4 decades had steadily improved. The life expectancy of the average Syrian in 2012 was 75.7 years, compared to 56 years in 1970. As a result of the civil war, this trend has reversed, with the life expectancy reduced by 20 years from the 2012 level. The Syrian government and its allies have specifically targeted the health care infrastructure not under government control. (Disaster Med Public Health Preparedness. 2018;12:23–25)
Cultural Continuity and Social Resistance: The Chronology of Megalithic Funerary Practices in Southern Iberia
Authors: Aranda Jiménez Gonzalo , Lozano Medina Águeda , Díaz-Zorita Bonilla Marta , Sánchez Romero Margarita , Escudero Carrillo Javier
Published: July 2017

Inspired by the biographical approach to the study of material culture, a radiocarbon dating programme was undertaken to explore the chronology and temporality of the megalithic monuments in south-eastern Iberia. Instead of one or two dates per tomb, the normal way of approaching this complex issue, we carried out a complete radiocarbon dating series of single tombs based on human remains. We focused our attention on four tholos-type tombs in the cemetery of El Barranquete (Almería, Spain). According to the new radiocarbon series modelled in a Bayesian framework, four main conclusions can be drawn: that the cemetery shows a very long period of funerary activity, which began in the late fourth millennium and ended in the last centuries of the second millennium calbc; that continuity of ritual practices attained an unexpected importance during the Bronze Age; that interments, which fall into cultural periods that would be unthinkable if only the typological properties of the grave goods were considered, occurred; and that each tomb had a complex and very different biography.
Variable Case Detection and Many Unreported Cases of Surgical-Site Infection Following Colon Surgery and Abdominal Hysterectomy in a Statewide Validation
Authors: Calderwood Michael S. , Huang Susan S. , Keller Vicki , Bruce Christina B. , Kazerouni N. Neely , Janssen Lynn
Published: July 2017

OBJECTIVE

To assess hospital surgical-site infection (SSI) identification and reporting following colon surgery and abdominal hysterectomy via a statewide external validation

METHODS

Infection preventionists (IPs) from the California Department of Public Health (CDPH) performed on-site SSI validation for surgical procedures performed in hospitals that voluntarily participated. Validation involved chart review of SSI cases previously reported by hospitals plus review of patient records flagged for review by claims codes suggestive of SSI. We assessed the sensitivity of traditional surveillance and the added benefit of claims-based surveillance. We also evaluated the positive predictive value of claims-based surveillance (ie, workload efficiency).

RESULTS

Upon validation review, CDPH IPs identified 239 SSIs following colon surgery at 42 hospitals and 76 SSIs following abdominal hysterectomy at 34 hospitals. For colon surgery, traditional surveillance had a sensitivity of 50% (47% for deep incisional or organ/space [DI/OS] SSI), compared to 84% (88% for DI/OS SSI) for claims-based surveillance. For abdominal hysterectomy, traditional surveillance had a sensitivity of 68% (67% for DI/OS SSI) compared to 74% (78% for DI/OS SSI) for claims-based surveillance. Claims-based surveillance was also efficient, with 1 SSI identified for every 2 patients flagged for review who had undergone abdominal hysterectomy and for every 2.6 patients flagged for review who had undergone colon surgery. Overall, CDPH identified previously unreported SSIs in 74% of validation hospitals performing colon surgery and 35% of validation hospitals performing abdominal hysterectomy.

CONCLUSIONS

Claims-based surveillance is a standardized approach that hospitals can use to augment traditional surveillance methods and health departments can use for external validation.

Infect Control Hosp Epidemiol 2017;38:1091–1097
Antibiotic Overuse is a Major Risk Factor for Clostridium difficile Infection in Surgical Patients
Authors: Bernatz James T. , Safdar Nasia , Hetzel Scott , Anderson Paul A.
Published: July 2017

Clostridium difficile infection (CDI) is associated with increased cost, morbidity, and mortality in postoperative patients. Variable rates of postoperative CDI are reported among 4 surgical specialties during the 30-month study period. Risk factors for CDI include antibiotic use, increased ASA score, and increased admissions in the past year.

Infect Control Hosp Epidemiol 2017;38:1254–1257
FROM SUZHOU TO SHANGHAI: A TALE OF TWO SYSTEMS
Authors: Marmé Michael
Published: July 2017

Scholars have long assumed that the opening of Shanghai as a treaty port in 1843, followed by the disruption caused by the Taiping Rebellion, led to an abrupt restructuring of China's internal organization and a fundamental change in its relation to the outside world. Looking at developments at Suzhou and Shanghai over the long nineteenth century in parallel, this study argues that this was in fact a far later and much more gradual process than we have heretofore appreciated, the decisive breaks occurring at least a half-century later than usually assumed.
Crassicauda boopis in a fin whale (Balaenoptera physalus) ship-struck in the eastern North Atlantic Ocean
Authors: LEMPEREUR LAETITIA , DELOBELLE MORGAN , DOOM MARJAN , HAELTERS JAN , LEVY ETIENNE , LOSSON BERTRAND , JAUNIAUX THIERRY
Published: July 2017

On 9 November 2015, a juvenile male fin whale of 11·60 m length was observed on the bulb of a merchant vessel in the Channel Terneuzen – Ghent (The Netherlands – Belgium). A severe parasitosis was present in the right heart ventricle and caudal caval vein. Parasites were identified as Crassicauda boopis based on macroscopic and microscopic observations. The sequence of the 18S rRNA gene obtained from the parasite samples was 100% similar to the sequence of the 18S rRNA gene from Crassicauda magna available on GenBank. While adults of C. boopis and C. magna are morphologically distinct and found at different locations in the body, the molecular analysis of the 18S rRNA gene seems insufficient for reliable species identification. Although numerous C. boopis were found, the cause of death was identified as due to the collision with the ship, as suggested by the presence of a large haematoma, and the absence of evidence of renal failure. The young age of this whale and the absence of severe chronic reaction may suggest that the infestation was not yet at an advanced chronic stage.
Are You Working Vigorously? Adaptation and Validation of the Thai Version of Shirom-Melamed Vigor Scale
Authors: Boonyasiriwat Watcharaporn , Srisuwannatat Paradee , Puttaravuttiporn Vipavee
Published: July 2017

Supporting the application of positive psychology in the workplace, the Shirom Melamed Vigor Scale (SMVS), which assesses vigorous feelings at work, was adapted to the Thai context. The Thai SMVS contains 14 items as in the original scale and was validated using a sample of 585 employed participants in Thailand. Results of a confirmatory factor analysis are consistent with the conceptual model of vigour as consisting of physical strength, cognitive liveliness, and emotional energy, with a suggestion that a 13-item scale can also be used. As expected, vigour has been found to be conceptually distinct from some similar constructs, and independent from job burnout. Vigour also showed unique predictive effects on employees’ health. These results support the previously-proposed conceptual framework of vigour and indicate crucial roles of positive emotion in the work setting. In concordance with a positive organisational psychology approach, applications of the Thai vigor scale are discussed with respect to its potential for enhancing employees’ wellbeing and productivity.
Vitamin D deficiency, oxidative stress and antioxidant status: only weak association seen in the absence of advanced age, obesity or pre-existing disease
Authors: Wang Erica W. , Siu Parco M. , Pang Marco Y. , Woo Jean , Collins Andrew R. , Benzie Iris F. F.
Published: July 2017

Vitamin D deficiency (plasma 25-hydroxycholecalciferol (25(OH)D)<50 nmol/l) is highly prevalent, increases risk of non-communicable diseases (NCD) and associates with increased oxidative stress in obese subjects, the elderly and patients suffering from NCD. If confirmed as an independent driver of oxidative stress, nutritional and other public health strategies to improve vitamin D status would be strongly supported. We investigated vitamin D/oxidative stress links without the confounding effects of advanced age, obesity, smoking or pre-existing disease. Plasma 25(OH)D and biomarkers of oxidative stress and antioxidant status (plasma allantoin, oxidised LDL, ferric reducing antioxidant power (FRAP), ascorbic acid, urine 8-oxo-7,8-dihydro-2'-deoxyguanosine) were measured in fasting samples from 196 consenting, healthy adults aged 18–26 years. Correlation between 25(OH)D and each biomarker as well as biomarker differences across 25(OH)D quartiles and groups (<25/25–49/≥50 nmol/l) were investigated. Median 25(OH)D was 40 nmol/l; >70 % of participants were vitamin D deficient. No significant correlations and no biomarker differences across 25(OH)D quartiles or groups were seen except for total antioxidant status. A weak direct association (r0·252,P<0·05) was observed between 25(OH)D and FRAP, and those in the lowest 25(OH)D quartile and group had significantly lower FRAP values. Results did not reveal a clear link between vitamin D status and oxidative stress biomarkers in the absence of advanced age, obesity and disease, though some evidence of depleted antioxidant status in those with vitamin D deficiency was seen. Poor antioxidant status may pre-date increased oxidative stress. Study of effects of correction of deficiency on antioxidant status and oxidative stress in vitamin D-deficient but otherwise healthy subjects is needed.
Larval species composition and genetic structures ofCarposina sasakii,Grapholita dimorpha, andGrapholita molestafrom Korea
Authors: Kwon D.H. , Kwon H.K. , Kim D.H. , Yang C.Y.
Published: July 2017

Rapid determination of the larval species composition and understanding of their genetic structure is important to establish the appropriate management system for multiple species infesting in fruits. We established accurate and rapid diagnostic methods based on multiplex polymerase chain reaction (PCR) diagnostic techniques to discriminate the three major lepidopteran species in orchard,Carposina sasakii,Grapholita dimorpha, andGrapholita molesta. Each species was identified by amplifying species-specific PCR products (375 bp forC. sasakii, 125 and 234 bp forG. dimorpha, and 125 bp forG. molesta). Based on species composition analysis from six types of infested fruits,G. dimorphaconstituted the highest proportion (47.8%), followed by 35.2 and 13.5% forG. molestaandC. sasakii, respectively. Interestingly, high prevalence was found inG. dimorphaandG. molestafor plum and peach, respectively. Based on genetic diversity analysis, the three insect species exhibited moderate or high haplotype diversity and low nucleotide diversity, ranging from 0.319 to 0.699 and 0.0006 to 0.0045, respectively. Demographic expansion was not detected according to either a neutrality test or mismatch distribution analysis. Moreover, no significant genetic structure corresponding to province, host plant, fruit type, or collection period was observed. These results suggest that the population of each species would have high dispersal ability following fruit-generating periods via intrinsic host adaptation ability regardless of the spatial and temporal conditions. Determination of larval composition on fruit is valuable for establishing appropriate management systems that take the species into consideration; additionally, population genetic approaches can be utilized to understand the effects of environmental factors (province, host fruit, fruit type, etc.) on population structures.
Eustachian tube dysfunction leading to middle-ear pathology in patients on chronic mechanical ventilation
Authors: Ilan O , Marcus E-L , Cohen Y , Farkash T , Levy R , Sasson A , Adelman C
Published: July 2017

Objective:

This study aimed to investigate the prevalence of and risk factors for Eustachian tube dysfunction leading to middle-ear pathology in patients on chronic mechanical ventilation via tracheostomy tube.

Methods:

A total of 40 patients on chronic ventilation were included in a prospective cohort study. Middle-ear status was determined by tympanometry. Tympanograms were categorised as types A, B or C; types B and C were defined as middle-ear pathology.

Results:

In all, 57 ears of 40 patients were examined. Disease was found in at least 1 ear in 26 out of 40 patients. Middle-ear pathology was found in 25 out of 34 patients who were tube fed (via nasogastric tube or percutaneous endoscopic gastrostomy)vs1 patient out of the 6 fed orally (p= 0.014), and in 23 out of 31 with conscious or cognitive impairmentvs3 out of 9 cognitively intact patients (p= 0.044).

Conclusion:

Middle-ear pathology is common in patients on chronic mechanical ventilation via tracheostomy tube. The highest prevalence was in those with impaired consciousness or cognition, and oral feeding appeared protective.
Three-dimensional magnetohydrodynamic equilibria with continuous magnetic fields
Authors: Hudson S. R. , Kraus B. F.
Published: July 2017

A brief critique is presented of some different classes of magnetohydrodynamic equilibrium solutions based on their continuity properties and whether the magnetic field is integrable or not. A generalized energy functional is introduced that is comprised of alternating ideal regions, with nested flux surfaces with an irrational rotational transform, and Taylor-relaxed regions, possibly with magnetic islands and chaos. The equilibrium states have globally continuous magnetic fields, and may be constructed for arbitrary three-dimensional plasma boundaries and appropriately prescribed pressure and rotational-transform profiles.
Contribution of scaling up nutrition Academic Platforms to nutrition capacity strengthening in Africa: local efforts, continental prospects and challenges
Authors: Laar Amos K. , Aryeetey Richmond N. O. , Annan Reginald , Aryee Paul A. , Amagloh Francis K. , Akparibo Robert , Laar Matilda E. , Amuna Paul , Zotor Francis B.
Published: July 2017

Addressing contemporary nutrition problems often requires application of knowledge from multiple disciplines. The scaling up nutrition (SUN) movement harnesses multiple sectors for effective global and in-country planning and implementation. Although the role of knowledge networks (academia and research institutions) is recognised, the how of engaging knowledge networks in the current SUN architecture is only now becoming apparent. For relevant sectors to play their roles effectively, observed capacity gaps, particularly in developing country settings, need to be addressed. The present paper presents the work being undertaken by the Ghana SUN Academic Platform (AP), a local knowledge network, towards strengthening nutrition capacity in Ghana. The AP presently provides technical support, evidence and capacity towards scaling up effective nutrition interventions in Ghana and beyond. The data presented draws heavily on the observations and collective experiences of the authors in practice, complemented by a review of relevant literature. The ultimate goal of the AP is to build capacity of professionals from nutrition and cognate sectors (including planning, agriculture, health, economics, research and academia). This is an essential ingredient for effective and durable SUN efforts. The paper recognises that both disciplinary and interdisciplinary capacity is required for effective SUN efforts in Africa, and offers an approach that utilises cross-sector/inter-professional, peer-learning and experiential learning initiatives.
Architectural Hybridity in Iberian Southeast Asia, 1580–1640
Authors: Luengo Pedro
Published: July 2017

The Union of the Iberian Crowns (1580–1640) promoted a wider cultural exchange between Portuguese and Spanish Asian settlements in Asia. This paper identifies the remarkable circulation of artisans and patrons and the development of new building techniques during this period, which allowed for a shared cultural dialogue that may be best described as forms ofmestizage. So, it tries to address the mobility of patrons and architects, which helps explain the diffusion of techniques and models. The first case shows how cultural dialogue promoted new techniques from local traditions and materials, which were later used in neighbouring settlements. The second demonstrates the role these mixed solutions played in the creation of the image of apurestate, in the form of public palaces, amestizosociety, mainly in urban houses, and a local cultural resistance, keeping traditional housing forms in the native quarters. Thanks to this approach, the currently preserved built heritage can be seen not only as a European cultural transfer but also as the result of a fruitful global dialogue.
Imperial Perceptions and Circulation in the Portuguese Atlantic World (1620s–1660s)
Authors: da Cruz Miguel Dantas
Published: July 2017

Among the more emphasised aspects of the Atlantic history are the mobility of ideas and goods but also the endless movement of peoples that linked the margins of the ocean and gave the Atlantic basin an indisputable cohesion. Within the theoretical framework of the subfield of Atlantic history, this study addresses the way the imperial perceptions shaped the migratory patterns of the Portuguese Atlantic, notably the transoceanic behaviour of the men who volunteered to defend its scattered territories. During a particularly difficult period in the mid-seventeenth century, the hierarchical ambiguities of Portuguese empire and its religiously charged military thought, in conjunction with the prevalent political culture of service, promoted a constant back and forth across the ocean that revealed the conceptual unity of the Portuguese Atlantic world. For these men, for a while, there were no alluring centres and unappealing peripheries; the Atlantic was conceived of as a wide circulation space essentially free from mental or emotional prejudices.
PARTIAL LIABILITY
Authors: Kaiserman Alex
Published: July 2017

In most cases, liability in tort law isall-or-nothing—a defendant is either fully liable or not at all liable for a claimant's loss. By contrast, this paper defends a causal theory ofpartialliability. I argue that a defendant should be held liable for a claimant's loss only to the degree to which the defendant's wrongdoing contributed to the causing of the loss. I ground this principle in a conception of tort law as a system of corrective justice and use it to critically evaluate different mechanisms for “limiting” liability for consequences of wrongdoing and for “apportioning” liability between multiple wrongdoers.
Studying texts in a second language: The importance of test type
Authors: VANDER BEKEN HELEEN , BRYSBAERT MARC
Published: July 2017

Little is known about the extent to which information encoding and retrieval differ between materials studied in first and second language (L1 and L2). In this study we compared memory for short, expository texts in L1 and L2, tested with a free recall test and a true/false judgement test. Our results show that students performed at the same level on the recognition test in both languages but not on the free recall test, with much lower performance in L2 than in L1, defined here as the dominant language. The L2 recall cost suggests that students’ performance may be underestimated if they are exclusively tested with essay-type exams in L2.
Is food store type associated with the consumption of ultra-processed food and drink products in Brazil?
Authors: Machado Priscila Pereira , Claro Rafael Moreira , Martins Ana Paula Bortoletto , Costa Janaína Calu , Levy Renata Bertazzi
Published: July 2017

Objective

To analyse the association between food store type and the consumption of ultra-processed products in Brazil.

Design

Data from the 2008–2009 Household Budget Survey involving a probabilistic sample of 55 970 Brazilian households. Food stores were grouped into nine categories. Foods and drinks were grouped according to characteristics of food processing. The contribution of each food store type to the total energy acquired from each food processing group, and according to quintiles of consumption of ultra-processed products, was estimated. Exploratory factor analysis was conducted to identify a pattern of food store usage. Linear regression models were performed to estimate the relationship between the purchase pattern and the consumption of ultra-processed products.

Results

In line with their larger market share, supermarkets accounted for 59 % of total energy and participated most in acquisition for three food groups, with emphasis on ultra-processed products (60·4 % of energy). The participation of supermarkets in total purchase tended to increase in populations with higher consumption of ultra-processed products, while the participation of small markets and small producers tended to decrease. The purchase pattern characterized by use of traditional retail (street fairs and vendors, small markets, small farmers, butcheries) was associated with a smaller consumption of ultra-processed products.

Conclusions

Food policies and interventions aiming to reduce the consumption of ultra-processed products should consider the influence of supermarkets on the consumption of these products. A purchase pattern based on traditional retail constitutes an important tool for promoting healthy eating in Brazil.
Perigraft hygroma – a rare cause of post-EVAR aneurysm growth
Authors: Strouther Nicholas , Oshin Olufemi , Fisher Robert , McWilliams Richard , Torella Francesco
Published: July 2017

Abstract. Development of perigraft hygromas following repair of abdominal aortic aneurysms is extremely rare. A case is presented of a patient who was found to have a large hygroma despite two re-interventions on a previous EVAR.
Hexagonal boron nitride nanomechanical resonators with spatially visualized motion
Authors: Zheng Xu-Qian , Lee Jaesung , Feng Philip X.-L.
Published: July 2017

Atomic layers of hexagonal boron nitride (h-BN) crystal are excellent candidates for structural materials as enabling ultrathin, two-dimensional (2D) nanoelectromechanical systems (NEMS) due to the outstanding mechanical properties and very wide bandgap (5.9 eV) of h-BN. In this work, we report the experimental demonstration of h-BN 2D nanomechanical resonators vibrating at high and very high frequencies (from ~5 to ~70 MHz), and investigations of the elastic properties of h-BN by measuring the multimode resonant behavior of these devices. First, we demonstrate a dry-transferred doubly clamped h-BN membrane with ~6.7 nm thickness, the thinnest h-BN resonator known to date. In addition, we fabricate circular drumhead h-BN resonators with thicknesses ranging from ~9 to 292 nm, from which we measure up to eight resonance modes in the range of ~18 to 35 MHz. Combining measurements and modeling of the rich multimode resonances, we resolve h-BN’s elastic behavior, including the transition from membrane to disk regime, with built-in tension ranging from 0.02 to 2 N m−1. The Young’s modulus of h-BN is determined to be EY≈392 GPa from the measured resonances. The ultrasensitive measurements further reveal subtle structural characteristics and mechanical properties of the suspended h-BN diaphragms, including anisotropic built-in tension and bulging, thus suggesting guidelines on how these effects can be exploited for engineering multimode resonant functions in 2D NEMS transducers.
Dynamically induced robust phonon transport and chiral cooling in an optomechanical system
Authors: Kim Seunghwi , Xu Xunnong , Taylor Jacob M. , Bahl Gaurav
Published: July 2017

The transport of sound and heat, in the form of phonons, can be limited by disorder-induced scattering. In electronic and optical settings the introduction of chiral transport, in which carrier propagation exhibits parity asymmetry, can remove elastic backscattering and provides robustness against disorder. However, suppression of disorder-induced scattering has never been demonstrated in non-topological phononic systems. Here we experimentally demonstrate a path for achieving robust phonon transport in the presence of material disorder, by explicitly inducing chirality through parity-selective optomechanical coupling. We show that asymmetric optical pumping of a symmetric resonator enables a dramatic chiral cooling of clockwise and counterclockwise phonons, while simultaneously suppressing the hidden action of disorder. Surprisingly, this passive mechanism is also accompanied by a chiral reduction in heat load leading to optical cooling of the mechanics without added damping, an effect that has no optical analog. This technique can potentially improve upon the fundamental thermal limits of resonant mechanical sensors, which cannot be attained through sideband cooling.
Light-absorbing organic carbon from prescribed and laboratory biomass burning and gasoline vehicle emissions
Authors: Xie Mingjie , Hays Michael D. , Holder Amara L.
Published: July 2017

Light-absorbing organic carbon (OC), also termed brown carbon (BrC), from laboratory-based biomass burning (BB) has been studied intensively to understand the contribution of BB to radiative forcing. However, relatively few measurements have been conducted on field-based BB and even fewer measurements have examined BrC from anthropogenic combustion sources like motor vehicle emissions. In this work, the light absorption of methanol-extractable OC from prescribed and laboratory BB and gasoline vehicle emissions was examined using spectrophotometry. The light absorption of methanol extracts showed a strong wavelength dependence for both BB and gasoline vehicle emissions. The mass absorption coefficients at 365 nm (MAC365, m2 g−1C) – used as a measurement proxy for BrC – were significantly correlated (p < 0.05) to the elemental carbon (EC)/OC ratios when examined by each BB fuel type. No significant correlation was observed when pooling fuels, indicating that both burn conditions and fuel types may impact BB BrC characteristics. The average MAC365 of gasoline vehicle emission samples is 0.62 ± 0.76 m2 g−1C, which is similar in magnitude to the BB samples (1.27 ± 0.76 m2 g−1C). These results suggest that in addition to BB, gasoline vehicle emissions may also be an important BrC source in urban areas.
Direct transfer of classical non-separable states into hybrid entangled two photon states
Authors: Jabir M. V. , Apurv Chaitanya N. , Mathew Manoj , Samanta G. K.
Published: July 2017

Hybrid entangled states, having entanglement between different degrees-of-freedom (DoF) of a particle pair, are of great interest for quantum information science and communication protocols. Among different DoFs, the hybrid entangled states encoded with polarization and orbital angular momentum (OAM) allow the generation of qubit-qudit entangled states, macroscopic entanglement with very high quanta of OAM and improvement in angular resolution in remote sensing. Till date, such hybrid entangled states are generated by using a high-fidelity polarization entangled states and subsequent imprinting of chosen amount of OAM using suitable mode converters such as spatial light modulator in complicated experimental schemes. Given that the entangled sources have feeble number of photons, loss of photons during imprinting of OAM using diffractive optical elements limits the use of such hybrid states for practical applications. Here we report, on a simple generic experimental scheme to generate hybrid entangled states in polarization and OAM through direct transfer of classical non-separable states of the pump beam in parametric down conversion process. As a proof of principle, using local non-separable pump states of OAM mode l = 3, we have produced quantum hybrid entangled states with entanglement witness parameter of ~1.25 ± 0.03 violating by 8 standard deviation.
Schematic eye-gaze cues influence infants’ object encoding dependent on their contrast polarity
Authors: Michel Christine , Pauen Sabina , Hoehl Stefanie
Published: July 2017

We examined infants’ sensitivity to eye-gaze direction and its influence on object processing in 4-month-old infants by manipulating low-level properties of gaze cues. Infants were presented with two kinds of stimuli that either did or did not cue novel objects. The movement of a schematic image of two eyes (two black circles each moving on a white oval background) led to an enhanced processing of the cued object. A cue with reversed polarity (two white circles each moving on a black oval background) elicited distinctly weaker effects. Results highlight infants’ specific sensitivity to isolated eye gaze which furthermore facilitates object encoding. It is suggested that this sensitivity relies on the typical perceptual pattern of eyes, the black pupil on a white sclera.
Cell Dispersal Influences Tumor Heterogeneity and Introduces a Bias in NGS Data Interpretation
Authors: Pongor Lőrinc , Harami-Papp Hajnalka , Méhes Előd , Czirók András , Győrffy Balázs
Published: July 2017

Short and long distance cell dispersal can have a marked effect on tumor structure, high cellular motility could lead to faster cell mixing and lower observable intratumor heterogeneity. Here we evaluated a model for cell mixing that investigates how short-range dispersal and cell turnover will account for mutational proportions. We show that cancer cells can penetrate neighboring and distinct areas in a matter of days. In next generation sequencing runs, higher proportions of a given cell line generated frequencies with higher precision, while mixtures with lower amounts of each cell line had lower precision manifesting in higher standard deviations. When multiple cell lines were co-cultured, cellular movement altered observed mutation frequency by up to 18.5%. We propose that some of the shared mutations detected at low allele frequencies represent highly motile clones that appear in multiple regions of a tumor owing to dispersion throughout the tumor. In brief, cell movement will lead to a significant technical (sampling) bias when using next generation sequencing to determine clonal composition. A possible solution to this drawback would be to radically decrease detection thresholds and increase coverage in NGS analyses.
Stable isotopes of carbon and nitrogen help to predict the belowground communities at a regional scale
Authors: Wang Bing , Wu Ying , Chen Dima
Published: July 2017

At the regional scale, although environmental factors are known to shape the distributions of belowground communities in terrestrial ecosystems, these environmental factors account for relatively low percentages of the variation in belowground communities. More of this variation might be explained by considering ecosystem stable isotopic values, which can provide insight into environmental conditions. Here, we investigated ecosystem (plant and soil) δ13C and δ15N values and belowground communities (microbes and nematodes) as well as environmental factors (climates, soils, and plants) across the Mongolian Plateau. The regression analyses showed that plant isotopic values were more closely associated with belowground communities than soil isotopic values, while ecosystem δ13C values were more closely associated with the belowground communities than ecosystem δ15N values. We also found isotopic values were more closely associated with nematode communities than microbial communities. Variation partioning analyses indicated that environmental variables together explained 16–45% of total variation in belowground communities. After isotopic variables were added as predictors to the variation partition analyses, the explanation of the variance was improved by14–24% for microbial communities and was improved by 23–44% for nematode communities. These findings indicate that isotopic values could be used to predict the properties of belowground communities at a regional scale.
Huaier extract restrains the proliferative potential of endocrine-resistant breast cancer cells through increased ATM by suppressing miR-203
Authors: Gao Sumei , Li Xiaoyan , Ding Xia , Jiang Liyu , Yang Qifeng
Published: July 2017

Endocrine therapy is one of the main treatments for breast cancer patients in the early stages. Tamoxifen and fulvestrant are the major drugs of endocrine therapy for breast cancer patients. However, acquired drug resistance often caused treatment failure and relapse for patients, which is a major clinical problem. We investigated whether Huaier extract had effects on endocrine-resistant breast cancer cells. In our study, we aimed to demonstrate the inhibitory effects of Huaier extract on tamoxifen-resistant cells (M7-TR) and fulvestrant-resistant cells (M7-FR). Using MTT and clone formation assays, we found that Huaier extract could inhibit the proliferation in M7-TR and M7-FR cells. Flow cytometry and western blotting illustrated that Huaier extract could induce G0/G1 arrest in both endocrine-resistant breast cancer cells. Mechanistically, we present that Huaier extract significantly increased ataxia telangiectasia mutation (ATM) via down-regulation of miR-203. Huaier extract also had the inhibitory effects on tumour growth in vivo in a xenograft mouse model. These results demonstrated that Huaier extract could inhibit the proliferation of M7-TR and M7-FR cells by increasing ATM via suppression of miR-203.
Shape dependent cytotoxicity of PLGA-PEG nanoparticles on human cells
Authors: Zhang Bokai , Sai Lung Ping , Zhao Saisai , Chu Zhiqin , Chrzanowski Wojciech , Li Quan
Published: July 2017

We investigated the influence of nanoparticles’ shape on the physiological responses of cells, when they were fed with spherical and needle-shaped PLGA-PEG nanoparticles (the volume of the nanoparticles had been chosen as the fixed parameter). We found that both types of NPs entered cells via endocytosis and upon internalization they stayed in membrane bounded vesicles. Needle-shaped, but not the spherical-shaped NPs were found to induce significant cytotoxicity in the cell lines tested. Our study evidenced that the cytotoxicity of needle-shaped NPs was induced through the lysosome disruption. Lysosome damage activated the signaling pathways for cell apoptosis, and eventually caused DNA fragmentation and cell death. The present work showed that physiological response of the cells can be very different when the shape of the fed nanoparticles changed from spherical to needle-like. The finding suggests that the toxicity of nanomaterials also depends on their shape.
Continuous flow production of concentrated hyperpolarized xenon gas from a dilute xenon gas mixture by buffer gas condensation
Authors: Imai Hirohiko , Yoshimura Hironobu , Kimura Atsuomi , Fujiwara Hideaki
Published: July 2017

We present a new method for the continuous flow production of concentrated hyperpolarized xenon-129 (HP 129Xe) gas from a dilute xenon (Xe) gas mixture with high nuclear spin polarization. A low vapor pressure (i.e., high boiling-point) gas was introduced as an alternative to molecular nitrogen (N2), which is the conventional quenching gas for generating HP 129Xe via Rb-Xe spin-exchange optical-pumping (SEOP). In contrast to the generally used method of extraction by freezing Xe after the SEOP process, the quenching gas separated as a liquid at moderately low temperature so that Xe was maintained in its gaseous state, allowing the continuous delivery of highly polarized concentrated Xe gas. We selected isobutene as the candidate quenching gas and our method was demonstrated experimentally while comparing its performance with N2. Isobutene could be liquefied and removed from the Xe gas mixture using a cold trap, and the concentrated HP 129Xe gas exhibited a significantly enhanced nuclear magnetic resonance (NMR) signal. Although the system requires further optimization depending on the intended purpose, our approach presented here could provide a simple means for performing NMR or magnetic resonance imaging (MRI) measurements continuously using HP 129Xe with improved sensitivity.