bluuebunny/crossref_metadata_2025 huggingface dataset:
Does Digitalization Lead to Better Transparency: Bibliometric Approach
Authors: Kostetskyi Pavlo
Published: November 2021

In recent years, digitalization has been an important factor in developing political, economic, social, and cultural relations. The rapid growth of digital technologies in global and national contexts leads to significant quantitative and qualitative changes in the economic development of countries. Digitalization leads to better transparency and is also related to new damages to the national economy. Thus, this research deals with the identification of interconnectedness between digitalization and transparency. Fulfillment of this task is realized with the VOSviewer bibliometric tool based on the analysis of 320 Scopus articles on “transparency” and “digitalization” in 1999-2021. Analysis of the dynamic of publications on transparency and digitalization allows concluding that there were only several publications a year in 1999-2009. In 2010-2018 the number of relevant publications demonstrated considerable growth, while in 2019-2021, there was a boost of scientific interest to the cohesion between transparency and digitalization. The bibliometric analysis allows pointing out that there is a strong relationship between transparency and digitalization. Basically, under network analysis, six clusters of research were identified, which focused on the implementation of digital technologies in business, logistics, public governance, the financial sphere, information management, and personal privacy. Moreover, considering visualization results, it might be concluded that more recent publications on transparency and digitalization are focused on the research of blockchain technologies, supply technologies, and artificial intelligence. The density visualization showed that the most relevant keywords in publications on transparency and digitalization are digitalization, blockchain, and industry 4.0. These bibliometric results might create a theoretical background on clarification of scale up to which development of digital sphere does not damage national security.
Towards Organizational Development In Digital Organizational Twin
Authors: Skrynnyk Olena
Published: November 2021

Sustained continuous monitoring and replication of organizational development in digital organizational twins is of particular importance for labour-intensive enterprises and also those in which reciprocal relations between social, corporate, normative and performative aspects assume the leading role. The main purpose of the research is the developing of a digital representation of organizational processes, which focuses on the performance, working activities, organizational issues, behaviour and interactions between of the organizational members. Consequently, the objectives of research include the monitoring of current research state, concept and design of a digital twin. The implementation of digital organizational twin should improve considering timely optimization of proactive and reactive organizational development measures in the company in relation to the core variables of the 7S model. The created digital twin should map the dynamics of organizational development, as well as concomitant and deviating processes. Systematization literary sources and approaches for the digital replication of organizational development issues indicates the lack of publications on research and diffuse distribution of scientific interest. The initial design of organizational development in the digital twin is based on four main objects and limited to a certain number of investigated parameters. This paper compare the conventional and digitalized organizational development process, explain the data flow in digital organizational twin, the design of organizational development in the digital organizational twin, provide an overview of the individual facets of organizational development, list the parameterization models and exemplarily illustrate the visualization of selected parameters. The results of the research can be useful for the expansion of the tension bridge between organisational development and technologies and the development of new potentials for the study of socio-technical effects in companies. This can be extended to include the other facets of business management and supplemented by the connection of other technological resources.
The Theory Of International Tax Competition: Comparative Analysis
Authors: Tiutinyk Inna , Mazurenko Oleksiy
Published: November 2021

The country’s ability to compete for financial and investment resources in the international arena depends on a number of factors that determine the favorable business environment, the level of protection of citizens’ rights, and the material well-being of the population. One of the indicators of the quality of the economic environment in the country is the level of tax competitiveness, as an integrated indicator that summarizes the indicators of the effectiveness of the tax system and the quality of tax policy. The article summarizes the arguments and counterarguments within the scientific discussion on the generalization of the main theories of formation and development of tax competitiveness of the country. The main purpose of the article is a comparative analysis of theories of tax competitiveness, determining the nature of the impact of tax competitiveness on indicators of economic and social development of the country. The methodological tools of the study are analytical and comparative methods, methods of generalization and synthesis. The object of research is the theory of the formation of tax competitiveness of the country. Based on the results of the analysis, a conclusion about the dual nature of the impact of tax competition on the country’s development indicators is made. Thus, tax competition reduces the level of taxation in countries, which negatively affects the amount of tax revenues and reduces the country’s potential to finance socio-economic development programs, stimulates the growth of labor migration and relocation of tax bases in jurisdictions with more attractive tax conditions. On the other hand, tax competition stimulates economic growth in the leading countries by increasing their investment attractiveness, business activity, stimulating certain sectors of the economy. The results of the study can be useful for public authorities in making decisions on identifying key vectors of public tax policy in the country.
Book review on Jody C. Baumgartner and Peter L. Francia (2020). Conventional Wisdom and American Elections: Exploding Myths, Exploring Misconceptions (Fourth Edition)
Authors: Gentle Paul
Published: November 2021

Eleven common topics are discussed in this book by the authors. Very detailed research is reviewed. This helps the read understand that some topics have some degree of consensus among professors of American political science. Furthermore, those topics that do not have a firm consensus of opinion are described, so that the reader can see where more research is needed and is indeed happening. This book is good for general readership as well as for undergraduate and graduate courses.
Corporate Governance And Its Effect On Professional Performance In Palestinian Private Universities, In Light Of Quality, Accreditation, And Classification Requirements
Authors: Buhaisi Dr. Issam , Al Damagh Dr. Zyad
Published: November 2021

Corporate governance has become a subject of heightened importance and attention in government policy circles, academia, and the popular press throughout all over the world. The purpose of the study is to examine the actual status of corporate governance principles in Palestinian private universities at Gaza Strip Governorates, in order to propose a framework of governance for these universities, in light of quality, accreditation and classification requirements for Palestinian universities issued by Palestinian Ministry of Higher Education. In Gaza Strip Governorates there are four private universities, the study covers all these four universities. To achieve the study objectives, the descriptive analytical approach was implemented. The study population includes all the 458, stockholders, academic and administrative fixed contract employees at the four private universities in Gaza Strip. the sample was a random sample of 200 employees (44% of the population). A special questionnaire was prepared and distributed for the sample, 182 completed and correct questionnaire copies were collected (91% of total sample). Data was collected using Statistical Package for the Social Sciences SPSS program. The main finding of the study demonstrates that there is a significant relationship between private universities performance and the application of corporate governance principles, quality and accreditation requirements and classification requirements of Ministry of Higher Education (MOHE), and applied corporate governance framework, and there is a middle level of adequacy of corporate governance principles adequacy at private universities in Gaza Governorates. These findings reflect the actual situation of all Palestinian private universities. Based on the study results, the researchers recommend to build national standards for university governance, aiming to accelerate the issuance of a guide to the governance of private universities. Also, promoting cultural and knowledge awareness regarding the governance of private universities. These recommendations will help Palestinian private universities to achieve higher performance quality in both academic and managerial aspects, this will improve the outcomes of these universities and will be reflected in the capabilities of their graduate students.
Competitiveness or complementarity: Analysis of agricultural trade between China and Brazil
Authors: Zhang Fenghe
Published: November 2021

The competitiveness and complementarity of trade reflect the advantages and disadvantages of exports and future trade trends. After China joined the WTO, the import and export volume of agricultural products has increased significantly, but the import volume and import growth rate have greatly exceeded the export volume and export growth rate. China is the world’s largest importer of agricultural products, and Brazil has become the world’s largest exporter of agricultural products. As a country with the largest increase in agricultural exports, China and Brazil have close agricultural trade exchanges. China has become Brazil’s largest importer of agricultural products for four consecutive years. In addition, both China and Brazil are BRIC countries; therefore, the establishment of a cooperation mechanism is more conducive to the development of agricultural trade. This study uses quantitative research methods to investigate the agricultural trade between China and Brazil by calculating the revealed comparative advantage index, trade complementarity index, and trade intensity index. The study found that due to the different endowments of agricultural resources and the significant differences in agricultural structure, China and Brazil’s agricultural trade competitiveness is weak and they are highly complementary. The main agricultural products exported by China are labor-intensive processed products (pulp and waste paper, textile fibers, vegetables and fruits), and the main agricultural products exported by Brazil are land-intensive products (oilseeds and oily fruits, vegetable oils, raw hides and furs). Complementary advantages in agricultural trade were analyzed. In the future, the two countries have huge potential for cooperation and development.
Alternanthera philoxeroides (Mart.) Griseb. (Amaranthaceae) en Navarra.
Authors: Peralta de Andrés Javier
Published: November 2021

Se aporta la primera cita de la especie exótica invasora Alternanthera philoxeroides en Navarra, planta con un alto potencial invasor. En la Península Ibérica se había observado con anterioridad en Galicia (A Coruña, en el año 2015), Cataluña (Barcelona, 2017) y Andalucía (Sevilla, 2021). Dado su potencial expansivo y difícil erradicación una vez extendida, convendría evaluar su distribución en Navarra para establecer medidas de control.
Response of climate change impact on streamflow: the case of the Upper Awash sub-basin, Ethiopia
Authors: Abdulahi Salih Duri , Abate Brook , Harka Arus Edo , Husen Sead Burhan
Published: November 2021

This paper discusses the response of climate change impact on future streamflow availability in Upper Awash River basin, Ethiopia. The change of climate was built using the CORDEX, RCM daily precipitation, maximum and minimum temperature under RCP4.5 and 8.5 scenarios. The climate model was examined in the historical period 1996–2015 for its ability to capture observed precipitation and temperature. Bias correction was performed on RCM temperature and precipitation to minimize the uncertainties that may occur from climate model projection. After the successful calibration and validation of the HBV hydrological model, streamflow was simulated for the periods of 2021–2040 and 2041–2060 and compared to streamflow of the baseline period 1996–2015 to investigate the changes. The results suggested that overall, following the precipitation increment, streamflow is expected to increase under both RCPs. The average monthly changes of streamflow are expected to increase by 40.1 and 29.4% under RCP4.5 and 16.9 and 18.5% under RCP8.5 scenarios for 2021–2040 and 2041–2060, respectively. Annual streamflow would increase by 28.5 and 23.95% under RCP4.5 and 8.5, respectively. The results of this work can help and inform the water resources planner and designer to frame an appropriate plan and management for the effective use of water in the future.
Identifying the spatio-temporal variations of Ulva prolifera disasters in all life cycle
Authors: Zhang Baowei , Guo Jianzhong , Li Ziwei , Cheng Yi , Zhao Yao , Boota Muhammad Waseem , Zhang Yaonan , Feng Liqiang
Published: November 2021

Since 2007, Ulva prolifera disasters have occurred every year in the South Yellow Sea of China, the largest green tide disaster in the world. The inter-annual differences make monitoring and early warning for such disasters difficult. This study used remote sensing data (2015–2019) to determine its spatio-temporal variations in all life cycles. The results showed a lay effect between the NDVI-mean and the coverage area of U. prolifera. The spatio-temporal distribution of U. prolifera showed stages and regional differences. From late April to early May, U. prolifera first emerged near the Subei Shoal. After development in the middle of the Yellow Sea, U. prolifera broke out in the eastern sea area of Shandong and Jiangsu, declined in the Shandong sea area, and disappeared near Qingdao. The cycle lasted for approximately 90 days. The sea surface temperature was the necessary condition for the disaster, and the sea wind field was the main driving force for its horizontal drift. This study overcomes the poor timing and continuity of remote sensing data in the monitoring of U. prolifera. It provides a theoretical reference for forecasting the outbreak period of U. prolifera and can aid policy-makers to avert such disasters in advance.
Treatment of poultry slaughterhouse wastewater using electrocoagulation: a review
Authors: Ngobeni Philadelphia Vutivi , Basitere Moses , Thole Andile
Published: November 2021

Poultry slaughterhouses are generally large consumers of fresh water, which is exhausted as wastewater characterized by a high concentration of biological oxygen demand (BOD), chemical oxygen demand COD, and fats, oil, and grease (FOG). Cost-effective methods are required for the treatment of poultry slaughterhouse wastewater, with the aim of attaining a high quality effluent that can be reused in industrial processes to promote sustainability. As compared to conventional treatment methods, electrocoagulation is an efficient and low-cost system. Electrocoagulation is environmentally friendly, treating wastewater without the need of chemicals, thus limiting secondary pollution. The metal anodes initiate electrochemical reactions for coagulation and flocculation. Its distinct advantages include compact installation and simple operation. This paper offers a comprehensive review of recent literature that has been dedicated to utilizing electrocoagulation for poultry slaughterhouse wastewater treatment. This paper also examines aspects such as theory, potential applications, current applications, as well as economical assessment of the technique.
Performance evaluation and substrate removal kinetics in a thermophilic anaerobic moving bed biofilm reactor for starch degradation
Authors: Shahzad H. M. A. , Khan S. J. , Habib Z.
Published: November 2021

A laboratory-scale anaerobic moving bed biofilm reactor (AnMBBR) was installed and operated at various hydraulic retention times (HRTs) of 20 to 1.5 d with surface area loading rate (SALR) of 0.86 to 11.43 gCOD/m2/d. Synthetic starch containing desizing wastewater with chemical oxygen demand (COD) of 12.75 g/L was prepared and fed into the reactor. Monod, modified Stover-Kincannon, Grau second-order and First-order substrate removal models were used to evaluate the results of AnMBBR. COD removal efficiency of bioreactor was dwindled by increasing the SALR or reducing the HRT. Decay coefficient (Kd) and yield coefficient (Y) for the Monod model were 0.027 1/d and 1.01 mgVSS/mgCOD, respectively. Maximum substrate utilization rate (Umax) and kinetic constant (Kb) for the Modified Stover-Kincannon model were estimated as 12.57 and 15.22 g/L/d, respectively. The constants (a and b) for the Grau second-order model were found to be 1.09 and 1.31 whilst kinetic coefficient for the Second-order model and First-order substrate removal model were 1.62 and 1.55 1/d, respectively. Modified Stover-Kincannon model and Grau second-order model were found to be the best fit for experimental data with R2 value of 0.99. The findings suggest that these models can be applied to predict the behaviour of AnMBBRs on various scales.
A Comprehensive Review on Medicinal Herbs and Novel Formulations for
the Prevention of Alzheimer’s Disease
Authors: Kaur Sarabjit , Singh Balbir , Singh Hasandeep , Singh Brahmjot , Kumar Navkaran , Rajput Ankita , Sidhu Disha , Kaur Amandeep , Arora Saroj
Published: November 2021

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases reported
in the aging population across the globe. About 46.8 million people are reported to have dementia,
and AD is mainly responsible for dementia in aged people. Alzheimer's disease (AD) is thought
to occur due to the accumulation of β-amyloid (Aβ) in the neocortex portion of the brain, nitric
oxide mediated dysfunctioning of blood-brain barrier, reduced activity of serine racemase enzyme,
cell cycle disturbances, damage of N-methyl-D-aspartate (NMDA) receptors and glutamatergic neurotransmission.
Modern treatment methods target the pathways responsible for the disease. To
date, solely symptomatic treatments exist for this disease, all making an attempt to counterbalance
the neurotransmitter disturbance. Treatments able to prevent or at least effectively modifying the
course of AD, referred to as ‘disease-modifying’ drugs, are still under extensive research. Effective
treatments entail a better indulgence of the herbal bioactives by novel drug delivery systems. The
herbal bioactive administered by novel drug delivery systems have proved beneficial in treating
this disease. This review provides detailed information about the role of medicinal plants and their
formulations in treating Alzheimer’s disease which will be highly beneficial for the researchers
working in this area.
Discovery of Novel Antimalarial Drugs Based on Thiosemicarbazone Derivatives: An In Silico Approach
Authors: Anant Arjun , Kaur Kamalpreet , Asati Vivek
Published: November 2021

Background:

Thiosemicarbazones belong to the group of semicarbazides, which contains a sulfur atom instead of an oxygen atom. Several studies have shown that they are effective against extracellular protozoans like Trichomonas vaginalis, Plasmodium falciparum, Trypanosoma cruzi, and other parasites.

Objective:

The current research involves pharmacophore model design, 3-D-QSAR, virtual screening, and docking studies, all of which are evaluated using various parameters.

Methods:

The present study was performed by Schrodinger software. A total of 40 ligands were selected for the development of 3D QSAR models. To predict the pIC50 values in 3D-QSAR analysis, the entire dataset was divided into two sets, training, and test sets, in a 7:3 ratio. The selected pharmacophore hypothesis has been used for the virtual screening study.

Results:

DHHRR_1 emerged as the best pharmacophore model with a survival score of 5.80. The 3D QSAR study showed a significant model with R2 = 0.91 and Q2 = 0.73. The series top-scoring compound 7e had a docking score of -10.44 and showed interactions with the amino acids, ARG-265, PHE-227, and LEU-531, required for activity. The developed pharmacophore model had been used for the screening of ZINC compounds, where ZINC26244107, ZINC13469100, ZINC01290725, and ZINC01350173 showed the best XP docking scores (-11.60, -11.27, -11.35, -10.52, respectively) while binding important amino acids ARG265, HIE185 and LEU 531 against plasmodium falciparum, PDB ID:5TBO. The docking study was further evaluated by taking standard drug chloroquine, showing similar binding interactions as shown by other compounds. The ADME studies showed the drug-likeness properties of the compounds.

Conclusion:

The results of the present study may be helpful for the future development of antimalarial compounds against Plasmodium falciparum.
Effect of cinnamon on blood sugar and anthropometric measurement in type two diabetes patients
Authors: Moyasser Sadiq Alaa , Salman Abid Najah , Hussein Jasim Ola , Mohammed Ali Besmah Mohammed Ali
Published: November 2021

There is some emerging evidence that suggests certain supplements help lower blood sugar levels. One of these is cinnamon, which exhibits characteristics that mimic insulin, such as the activity of biologically active substances to activate insulin receptor kinase, increasing glucose uptake, autophosphorylation of the insulin receptor, and glycogen synthase activity. To assess the effect of the cinnamon substance on lowering fasting blood sugar, modifying body weight, body mass index (B.M.I.), and waist circumference in type two diabetics. A randomized controlled intervention clinical trial. The study was conducted on 60 patients with type II diabetes mellitus; the study followed both gender patients for four weeks. The contributors were allocated randomly into a group that receives 2 g/d cinnamon substance (intervention group), and a group without cinnamon substance is given (control group). Fasting plasma glucose (F.P.G.) and anthropometrics measurement at the beginning (beforehand cinnamon supplementation and 4week at the end of the study duration). After 4 weeks of cinnamon taken, serum F.P.G. levels significantly improved (P≤0.0001). Anthropometric measurements (weight, height, B.M.I.) were reduced significantly (change mean ≤ P=0.001) for all. The Present study disclosed that supplementation of 2 gm cinnamon improves F.P.G. and has a good role in anthropometric indices (weight, waist circumference, B.M.I.).
A Transdiagnostic, Emotion Regulation App (Eda) for Children: Design, Development, and Lessons Learned
Authors: Moltrecht Bettina , Patalay Praveetha , Bear Holly Alice , Deighton Jessica , Edbrooke-Childs Julian
Published: November 2021

Background

Digital interventions, including mobile apps, represent a promising means of providing effective mental health support to children and young people. Despite the increased availability of mental health apps, there is a significant gap for this age group, especially for children (aged 10-12 years). Research investigating the effectiveness and development process of child mental health apps is limited, and the field faces persistent issues in relation to low user uptake and engagement, which is assumed to be a result of limited user involvement in the design process.

Objective

This study aims to present the development and design process of a new mental health app for children that targets their emotion regulation abilities. We describe the creation of a new interdisciplinary development framework to guide the design process and explain how each activity informed different app features.

Methods

The first 2 stages of the framework used a variety of methods, including weekly classroom observations over a 6-month period (20 in total); public engagement events with the target group (N=21); synthesis of the existing evidence as part of a meta-analysis; a series of co-design and participatory workshops with young users (N=33), clinicians (N=7), researchers (N=12), app developers (N=1), and designers (N=2); and finally, testing of the first high-tech prototype (N=15).

Results

For the interdisciplinary framework, we drew on methods derived from the Medical Research Council framework for complex interventions, the patient–clinician framework, and the Druin cooperative inquiry. The classroom observations, public engagement events, and synthesis of the existing evidence informed the first key pillars of the app and wireframes. Subsequently, a series of workshops shaped and reshaped the content and app features, including games, psychoeducational films, and practice modules. On the basis of the prototype testing sessions, we made further adjustments to improve the app.

Conclusions

Although mobile apps could be highly suitable to support children’s mental health on a wider scale, there is little guidance on how these interventions could be designed and developed. The involvement of young users across different design activities is very valuable. We hope that our interdisciplinary framework and description of the used methods will be helpful to others who are hoping to develop mental health apps for children and young people.
Fitness Tracker Information and Privacy Management: Empirical Study (Preprint)
Authors: Abdelhamid Mohamed
Published: November 2021

BACKGROUND

Fitness trackers allow users to collect, manage, track, and monitor fitness-related activities, such as distance walked, calorie intake, sleep quality, and heart rate. Fitness trackers have become increasingly popular in the past decade. One in five Americans use a device or an app to track their fitness-related activities. These devices generate massive and important data that could help physicians make better assessments of their patients’ health if shared with health providers. This ultimately could lead to better health outcomes and perhaps even lower costs for patients. However, sharing personal fitness information with health care providers has drawbacks, mainly related to the risk of privacy loss and information misuse.

OBJECTIVE

This study investigates the influence of granting users granular privacy control on their willingness to share fitness information.

METHODS

The study used 270 valid responses collected from Mtrurkers through Amazon Mechanical Turk (MTurk). Participants were randomly assigned to one of two groups. The conceptual model was tested using structural equation modeling (SEM). The dependent variable was the intention to share fitness information. The independent variables were perceived risk, perceived benefits, and trust in the system.

RESULTS

SEM explained about 60% of the variance in the dependent variable. Three of the four hypotheses were supported. Perceived risk and trust in the system had a significant relationship with the dependent variable, while trust in the system was not significant.

CONCLUSIONS

The findings show that people are willing to share their fitness information if they have granular privacy control. This study has practical and theoretical implications. It integrates communication privacy management (CPM) theory with the privacy calculus model.
Discovery of Arthritis in Psoriasis Patients for Early Rheumatological Referral (DAPPER): Protocol for a Longitudinal Observational Study (Preprint)
Authors: van Hal Tamara W , Van den Reek Juul MPA , Groenewoud Hans MM , Pasch Marcel C , Van den Hoogen Frank HJ , Wenink Mark H , De Jong Elke MGJ
Published: November 2021

BACKGROUND

One in three patients with psoriasis will develop psoriatic arthritis (PsA). If left untreated, this can lead to pain, impaired function, and irreversible joint damage. Timely recognition and referral to a rheumatologist are therefore key. However, current methods used to screen patients with psoriasis for those who might benefit from referral to a rheumatologist are not performing well enough.

OBJECTIVE

The Discovery of Arthritis in Psoriasis Patients for Early Rheumatological Referral (DAPPER) study is designed to determine the prevalence of PsA in a psoriasis population and to find parameters that can be used to develop a new or enhance an existing instrument for a rheumatological referral.

METHODS

DAPPER is a longitudinal observational study with a 1-year follow-up. Patients with psoriasis (N=300) who are treated at an outpatient dermatological clinic will be screened extensively for signs and symptoms of PsA by a trained rheumatologist. If there is clinical suspicion of PsA and the patient is not yet treated by a rheumatologist, referral to the Department of Rheumatology will follow for confirmation of the diagnosis and further care. After 1 year, data on changes in quality of life and PsA and psoriasis disease activity will be collected from the referred patients. The screening visit will be used to gather demographical and medical data, which can later be used to develop the aforementioned screening instrument.

RESULTS

Inclusion started in June 2019 and finished in June 2021. Follow-up with newly discovered patients with PsA is ongoing.

CONCLUSIONS

The DAPPER study is specifically designed to improve the detection of existing PsA in a dermatologic outpatient setting. Although internal validity will be tested, external validity will have to be checked using a second validation cohort. To predict the development of PsA in the future, longitudinal/prospective data collection is required and will be performed in a follow-up study (DAPPER-i).

CLINICALTRIAL

Dutch Trial Register NTR7604; https://www.trialregister.nl/trial/7397

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/31647
A Case Management Program at Home to Reduce Fall Risk in Older Adults (the MAGIC Study): Protocol for a Single-Blind Randomized Controlled Trial (Preprint)
Authors: Alberto Silsam Napolitano , Ansai Juliana Hotta , Janducci Ana Luísa , Florido João Vitor Businaro , Novaes Areta Dames Cachapuz , Caetano Maria Joana Duarte , Rossi Paulo Giusti , Tavares Larissa Riani Costa , Lord Stephen Ronald , Gramani-Say Karina
Published: November 2021

BACKGROUND

Individual case management programs may be particularly effective in reducing fall risk as they can better identify barriers and facilitators to health recommendations.

OBJECTIVE

This paper describes the protocol for a single-blind, parallel-group randomized controlled trial that aims to investigate the effectiveness and cost-effectiveness of a home-based multifactorial program targeting fall risk factors among people aged 60 years and over who have fallen at least twice in the past 12 months (the MAGIC trial).

METHODS

Older people with a history of at least 2 falls in the last year will be divided into 2 groups. The intervention group will receive case management at home for reducing the risk of falls, including a multidimensional assessment, explanation of fall risk factors, and elaboration and monitoring of an individualized intervention plan based on the identified fall risk factors, personal preferences, and available resources. The control group will be monitored once a month. Assessments (clinical data, fall risk awareness, physical and mental factors, safety at home, feet and shoes, and risk and rate of falls) will be carried out at baseline, after 16 weeks of the intervention, and at the posttrial 6-week and 1-year follow-up. After 16 weeks of the intervention, satisfaction and adherence to the intervention will also be assessed. Economic health will be evaluated for the period up to the posttrial 1-year follow-up.

RESULTS

Data collection started in April 2021, and we expected to end recruitment in December 2021. This case management program will address multifactorial assessments using validated tools and the implementation of individualized intervention plans focused on reducing fall risk factors.

CONCLUSIONS

This trial may provide reliable and valuable information about the effectiveness of case management for increasing fall risk awareness and reducing fall risk in older people.

CLINICALTRIAL

Brazilian Clinical Trials Registry (ReBec) RBR-3t85fd; https://ensaiosclinicos.gov.br/rg/RBR-3t85fd

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/34796
Association of Polypharmacy with Kidney Disease Progression in Adults with CKD
Authors: Kimura Hiroshi , Tanaka Kenichi , Saito Hirotaka , Iwasaki Tsuyoshi , Oda Akira , Watanabe Shuhei , Kanno Makoto , Shimabukuro Michio , Asahi Koichi , Watanabe Tsuyoshi , Kazama Junichiro James
Published: November 2021

Background and objective

Polypharmacy is common in patients with CKD and reportedly associated with adverse outcomes. However, its effect on kidney outcomes among patients with CKD has not been adequately elucidated. Hence, this investigation was aimed at exploring the association between polypharmacy and kidney failure requiring KRT.

Design, setting, participants, and measurements

We retrospectively examined 1117 participants (median age, 66 years; 56% male; median eGFR, 48 ml/min per 1.73 m2) enrolled in the Fukushima CKD Cohort Study to investigate the association between the number of prescribed medications and adverse outcomes such as kidney failure, all-cause mortality, and cardiovascular events in Japanese patients with nondialysis-dependent CKD. Polypharmacy and hyperpolypharmacy were defined as the regular use of 5–9 and ≥10 medications per day, respectively.

Results

The median number of medications was eight; the prevalence of polypharmacy and hyperpolypharmacy was each 38%. During the observation period (median, 4.8 years), 120 developed kidney failure, 153 developed cardiovascular events, and 109 died. Compared with the use of fewer than five medications, adjusted hazard ratios (95% confidence intervals) associated with polypharmacy and hyperpolypharmacy were 2.28 (1.00 to 5.21) and 2.83 (1.21 to 6.66) for kidney failure, 1.60 (0.85 to 3.04) and 3.02 (1.59 to 5.74) for cardiovascular events, and 1.25 (0.62 to 2.53) and 2.80 (1.41 to 5.54) for all-cause mortality.

Conclusions

The use of a high number of medications was associated with a high risk of kidney failure, cardiovascular events, and all-cause mortality in Japanese patients with nondialysis-dependent CKD under nephrology care.
Noninvasive Diagnosis of PLA2R-Associated Membranous Nephropathy
Authors: Bobart Shane A. , Han Heedeok , Tehranian Shahrzad , De Vriese An S. , Roman Juan Carlos Leon , Sethi Sanjeev , Zand Ladan , Andrades Gomez Cristina , Giesen Callen D. , Soler Maria Jose , Bomback Andrew S. , Fervenza Fernando C.
Published: November 2021

Background and objectives

Kidney biopsy is the current gold standard to diagnose membranous nephropathy. Approximately 70%–80% of patients with primary membranous nephropathy have circulating anti-phospholipase A2 receptor antibodies. We previously demonstrated that in proteinuric patients with preserved eGFR and absence of associated conditions (e.g., autoimmunity, malignancy, infection, drugs, and paraproteinemia), a positive anti-phospholipase A2 receptor antibody test by ELISA and immunofluorescence assay confirms the diagnosis of membranous nephropathy noninvasively. These data have not been externally validated.

Design, setting, participants, & measurements

The clinical and pathologic characteristics of patients with a positive anti-phospholipase A2 receptor antibody test at the Mayo Clinic, the University Hospital Vall D’Hebron (Barcelona), and the Columbia University Medical Center (New York) were retrospectively reviewed. Biopsy findings and presence or absence of a potential associated condition were assessed.

Results

From a total of 276 patients with positive anti-phospholipase A2 receptor serology, previously reported patients (n=33), kidney transplant recipients (n=9), pediatric patients (n=2), and patients without kidney biopsy (n=69) were excluded. Among the 163 remaining patients, associated conditions were identified in 47 patients, and 15 patients had diabetes mellitus. All 101 patients of the final cohort had a primary diagnosis of membranous nephropathy on kidney biopsy. In the 79 patients with eGFR≥60 ml/min per 1.73 m2, none of the biopsy findings altered diagnosis or management. Among the 22 patients with decreased eGFR, additional findings included superimposed acute interstitial nephritis (n=1).

Conclusions

In patients with preserved eGFR and absence of associated conditions or diabetes, a positive anti-phospholipase A2 receptor test by either ELISA >20 RU/ml or a positive immunofluorescence assay confirms the diagnosis of membranous nephropathy, precluding the requirement for a kidney biopsy.
Psychological Rehabilitation on a Patient with Breast and Arm Amputation: A Case Report
Authors: Castelli Isabela
Published: November 2021

We define amputation as a removal of totally or partial part of an organ. Amputations can be caused by chronic diseases as cancer, infection and diabetes, or by a traumatic accident. Where, we discuss the differences between the two types of amputation. This paper is a case report on an amputee patient, the consequences in short e long term. We suggest possible interventions for psychological professionals and multidisciplinary healthcare team. Also, we discuss the lack of academic production about traumatic amputations.
Discharges against medical advice and 30-day healthcare costs: an analysis of commercially insured adults
Authors: Onukwugha Eberechukwu , Gandhi Aakash Bipin , Alfandre David
Published: November 2021

Aim:Prior literature detailing the consequences of a discharge against medical advice (DAMA) has not focused on costs. We examine costs following a DAMA.Materials & methods:This retrospective cohort study utilized the IQVIA PharMetrics®Plus database to identify adults hospitalized during 2007–2015. We compared 30-day postdischarge healthcare costs between matched DAMA and routinely discharged groups.Results:Thirty-day healthcare costs for the DAMA group were US$1078 (95% CI: US$434–1730) higher, driven by inpatient readmissions (US$979; 95% CI: US$415–1543) and emergency department visits (US$79; 95% CI: US$56–102). Costs due to prescription drug fills were lower in the DAMA group.Conclusion:A DAMA was associated with higher 30-day postdischarge healthcare costs compared with routine discharges.
ОПЫТ ПРИМЕНЕНИЯ ОТЕЧЕСТВЕННОЙ ЭЛЕМЕНТНОЙ БАЗЫ ПРИ ПРОЕКТИРОВАНИИ АВАРИЙНО-СПАСАТЕЛЬНОЙ АППАРАТУРЫ
Authors: Епифанов М.А.
Published: November 2021

Рассмотрены основные характеристики аварийно-спасательной аппаратуры, ее КПА и пеленгаторов, варианты реализации на отечественных ЭРИ и возникающие при этом проблемы. Даны варианты решения, включая предложения в технические стандарты и спецификации КОСПАС-САРСАТ для представления в секретариат.
ПРОЕКТИРОВАНИЕ СЕМЕЙСТВА МИКРОКОНТРОЛЛЕРОВ ДЛЯ ПРИМЕНЕНИЯ В СИСТЕМАХ ИДЕНТИФИКАЦИИ, ХРАНЕНИЯ И АУТЕНТИФИКАЦИИ В ГОСУДАРСТВЕННОМ И КОММЕРЧЕСКОМ СЕКТОРЕ
Authors: Лебедев А.В.
Published: November 2021

В докладе производится попытка обоснования разработки единой микропроцессорной платформы для применения в системах идентификации, хранения и аутентификации в государственном и коммерческом секторе.
Indagaciones en torno al significado del oro en la cultura mapuche
Authors: Payàs Gertrudis , Villena Belén
Published: November 2021

This paper is part of an interdisciplinary project of which one of the objectives is the identification of gold extracting sites south of the city of Concepción. It develops the hypothesis, put forward by archaeological studies, of possible gold mining by the Incas or even earlier, as opposed to an historiographical theory which claims that the Incas did not cross the Biobio river. Against this background, and considering that in the sixteenth century mapudungun was spoken in a much larger area than the one covered by our project, i.e. Araucania, we inquire on the conspicuous presence of the word milla (gold) in Mapudungun, and the extent of its significance in mapuche society, a society that, according to records, does not seem to have given gold the symbolic and material importance it had in Andean cultures. We undertake a review of the state of the question and systematize linguistic data provided by the lexicons and other texts, in an attempt to resolve, as much as possible, the uncertainties surrounding the word milla and the cultural significance of gold in mapuche society.
Rafael Leoz y los diálogos transnacionales proporcionados por las Bienales de São Paulo
Authors: Lima Angélica , Victal Jane
Published: November 2021

El artículo discute la importancia de las Bienales de São Paulo como espacio de difusión de ideas e intercambios transnacionales en el área de la arquitectura y el urbanismo en las décadas de 1960 y 1970. Se empieza por abordar el carácter político y sociocultural de estos eventos desde sus inicios, cuando el campo de la arquitectura aún participaba como categoría en la Bienal de Arte de São Paulo. Desde estas consideraciones, se recorre la trayectoria del arquitecto español Rafael Leoz, quien, después de participar en la Exposición Internacional de Arquitectura de la sexta edición del festival, aún con pocos años alcanzó notoriedad en Brasil y América Latina, comienzo de una carrera de reconocimiento internacional. Sus investigaciones sobre la racionalización de la construcción, basada en conceptos geométricos modulares como fundamento para la solución de los problemas emergentes de la vivienda social, fueron reconocidas y difundidas entre algunos arquitectos y círculos académicos. El presente trabajo utiliza la síntesis bibliográfica, el análisis de documentación primaria de la Fundação Bienal y las fuentes periodísticas del período.
Editorial 47
Authors: Zamora Mora Centli
Published: November 2021

Con su número 47 Revista Bitácora quiere reafirmar su vocación natural y refundar su búsqueda para ofrecer a la comunidad arquitectónica los mejores contenidos, en tiempos de cambios constantes y a veces profundos. Esta edición se distingue por la variedad de enfoques y temas que ofrece a sus lectores la posibilidad de entretejer y relacionar diálogos diversos, todos concurrentes en la arquitectura o que parten de ella hacia múltiples materias. En una conversación con Nikola Jankovic, fundador de Editions B2, se expone una aproximación a la su labor editorial.A continuación, a través del análisis de la exposición Víctimas: Una obra de John Hejduk en el museo Leopoldo Rother de Bogotá, Colombia. Posteriormente, Alejandra Aguilar presenta una aproximación al pensamiento arquitectónico del filósofo alemán Peter Sloterdijk. Desde un análisis histórico, Tesoros invisibles plantea una relación directa entre la conquista de América y el surgimiento de la arquitectura como diciplina.

Nuestra sección de investigación abre con un artículo que presenta información inédita: La otra casa para Diego y Frida y el misterio de Eileen Gray en México aborda una construcción, ahora inexistente, que fue habitada por la icónica pareja del arte mexicano y proyectada por el arquitecto Xavier García Lascurain. En La identidad del paisaje urbano, Sergio García-Doménech establece una relación directa entre arquitectura, arte, espacio público y sociedad. Mediante la presentación del caso del Pettit Museu se reivindica la obra y figura de Antonio Bonet, arquitecto catalán involucrado en diversos movimientos arquitectónicos y urbanísticos del siglo XX. También en el siglo XX, presentamos una investigación en torno a la fábrica de neumáticos FATE en la capital de Argentina. Finalmente, Angélica Lima y Jane Victal rescatan la figura del arquitecto español Rafael Leoz y de su participación en las bienales de São Paulo durante los años 60 y 70.
Entre Lima y México. Palabras para Ricardo Melgar, In memoriam
Authors: Candia José Miguel
Published: November 2021

¿Qué vectores determinan nuestra vida de relación? ¿El azar, una voluntad ajena o los caprichos de la suerte? Quizá todo eso y otros factores que escapan al pretendido rigor de las agendas. Lo cierto es que a principios de 1976, buena parte de la izquierda sudamericana enfrentaba una opción extrema: abandonar el país de origen en las condiciones que se pudiera y salvar la vida o afrontar en la clandestinidad el avance de las fuerzas represivas. Las condiciones políticas de Argentina, Uruguay, Chile, Bolivia, Paraguay y Brasil eran de horror. Con matices, la situación de Perú, bajo el mandato del general Morales Bermúdez, mostraba un panorama menos degradado pero que se fue descomponiendo poco después de nuestra llegada a Lima. De esa forma y en condiciones precarias, un grupo de exiliados argentinos nos instalamos en Perú. No parecía tan grave lo que habíamos decidido; con cierta ingenuidad y buen ánimo, esperábamos que en un par de años la dictadura argentina se derrumbara. Lo que seguía era un retorno triunfal a Buenos Aires en cuatro horas de vuelo. Poca cosa, si se piensa en una época cargada de épica militante y horizontes maximalistas.
Face Mask Detection System
Authors: Sonwane Prof. A. T.
Published: November 2021

Abstract: There are many solutions to prevent the spread of the COVID-19 virus and one of the most effective solutions is wearing a face mask. Almost everyone is wearing face masks at all times in public places during the coronavirus pandemic. Coronavirus disease 2019 has affected the world seriously. One major protection method for people is to wear masks in public areas. The risk of transmission is highest in public places. However, there are only a few research studies about face mask detection based on image analysis. This paper aims to present a review of various methods and algorithms used for human recognition with a face mask. The proposed system to classify face mask detection using COVID-19 precaution both in images and videos using convolution neural network, TensorFlow and OpenCV to detect face masks on people. This system has various applications at public places, schools, etc. where people need to be detected with the presence of a face mask and recognize them and help society. Keywords: COVID-19, Tensorflow, OpenCV, Face Mask, Image Processing, Computer Vision
Emergent Replica Conformal Symmetry in Non-Hermitian SYK2Chains
Authors: Zhang Pengfei , Jian Shao-Kai , Liu Chunxiao , Chen Xiao
Published: November 2021

Recently, the steady states of non-unitary free fermion dynamics are found to exhibit novel critical phases with power-law squared correlations and a logarithmic subsystem entanglement. In this work, we theoretically understand the underlying physics by constructing solvable static/Brownian quadratic Sachdev-Ye-Kitaev chains with non-Hermitian dynamics. We find the action of the replicated system generally shows (one or infinite copies of)O(2)×O(2)symmetries, which is broken toO(2)by the saddle-point solution. This leads to an emergent conformal field theory of the Goldstone modes. We derive the effective action and obtain the universal critical behaviors of squared correlators. Furthermore, the entanglement entropy of a subsystemAwith lengthLAcorresponds to the energy of the half-vortex pairS∼ρslog⁡LA, whereρsis the total stiffness of the Goldstone modes. We also discuss special limits with more than one branch of Goldstone modes and comment on interaction effects.