bluuebunny/crossref_metadata_2025 huggingface dataset:
An implementation framework of blockchain-based hazardous waste transfer management system
Authors: Song Guanghan , Lu Yujie , Feng Haibo , Lin Han , Zheng Yang
Published: March 2021

The rapid increase in volume and types of hazardous waste (HW) due to China's rapid economic development makes it significant to conduct HW safety management. However, due to the information asymmetry between the regularors and regulated institutions,problems such as illegal dumping and statistical fraud are common in hazardous waste transfer (HWT) activities. Moreover, there is a severe problem of information isolated island among waste production companies, transportation companies, and treatment companies in the HW market. Promoting the monitoring and information traceability of the whole process of HWT is the main challenge for HW management. Blockchain provides an ideal solution to overcome the above challenges. This study builds a framework of the blockchain-based HWT management system, enabling government regulators to obtain relevant information in HWT and improve HW's convenience. The system is introduced in detail from the infrastructure, blockchain-service,functions and users, emphasizing six information management functions.Finally, the positive impact and various challenges encountered in implementing blockchain in HWT management were discussed. This study applies blockchain to the research field of HWT management, which expands the application of blockchain in the field of solid waste management with great theoretical and practical significance.
DFT study on the gold(I)-catalyzed cycloaddition and rearrangement reactions of allene-containing allylic silyl ether
Authors: Zhao Yamei , Huo MengDan , Zhou HongJi
Published: March 2021

The DFT calculation of the B3LYP level was carried out to explore the reaction mechanism of the synthesis of spirocyclo[4, 5]decane skeleton by gold-catalyzed allenyl compounds. The more accurate energy under the CH3CN solvent in the experiment is calculated by the single point energy of the SMD model. Computational studies have shown that the reaction consists of three main steps: intramolecular cycloaddition of the end group carbon atoms of allenyl and vinyl groups, the semipinacol rearrangement process in which the four-membered ring is reconstructed into the five-membered ring, the elimination reaction releases the catalyst and obtains the product. The calculation results show that Zheng et al. reported that the gold-catalyzed synthesis reaction can easily occur under the experimental conditions due to its low activation free energy (12.42–16.79 kcal/mol). Furthermore, it was found that the MOMO(CH2)2 substituent has higher reactivity than the corresponding reactant of the phenyl substituent.
What can the neurological manifestations of COVID-19 tell us : a meta-analysis
Authors: He Yuanyuan , Bai Xiaojie , Zhu Tiantian , Huang Jialin , Zhang Hong
Published: March 2021

Background

Covid-19 became a global pandemic in 2019. Studies have shown that coronavirus can cause neurological symptoms, but clinical studies on its neurological symptoms are limited. In this meta-analysis, we aim to gather and discuss COVID-19 various neurological symptoms of infection, and to assess the prevalence of each of the nervous system symptoms, and characterized by neurological in-depth discussions of nervous system damage mechanism, biomarkers and inspection methods, recovery and prognosis, and provide the research behind the potential target and direction.

Methods

We systematically searched all published English literature related to the neurological manifestations of COVID-19 from January 1, 2020 to November 20, 2020 in Pubmed, Embase, and Cochrane library.The keywords used were COVID-19 and terminology related to nervous system performance.All included studies were selected by two independent reviewers using EndNote and NoteExpress software, any disagreement was resolved by consensus or by a third reviewer, and the selected data was then collected for meta-analysis using a random-effects model.

Results

A total of 62 articles (n =32729) were included in the study, and the meta-analysis showed that the most common neurological manifestations of COVID-19 were altered mental status (39% ; 95% CI 0.17-0.64 ; I 2 98.59%), encephalopathy (37% ; 95% CI 0.17-0.60 ; I 2 97.36%), myalgia(31% ; 95% CI 0.25-0.38; I 2 98.79%), headache(30% ; 95% CI 0.22-0.37; I 2 99.28%), smell impairment(28% ; 95% CI 99.57% ; I 2 0.17-0.39), taste dysfunction (27% ; 95% CI 0.18 -0.38 ; I 2 99.35%), acute ischemic stroke (23% ; 95% CI 0.06-0.47 ; I 2 99.30%), alteration of consciousness(17% ; 95% CI 0.06-0.31 ; I 2 96.78%), dizziness (10% ; 95% CI 0.06-0.15; I 2 95.30%), intracerebral haemorrhage (7% ; 95% CI 0.02-0.14 ; I 2 93.64%), vision impairment(5% ; 95% CI 0.02-0.10 ; I 2 92.73%), seizure(2% ; 95% CI 0.01-0.04 ; I 2 84.67%).

Conclusions

Neurological symptoms are common and varied in Covid-19 infections, and a growing number of reports suggest that the prevalence of neurological symptoms may be increasing. In the future, the role of COVID-19 neurological symptoms in the progression of COVID-19 should be further studied, and its pathogenesis and assessment methods should be explored, so as to detect and treat early neurological complications of COVID-19 and reduce mortality.
Studies on Clarification of Coal Washery Effluent Using Polymeric Flocculants and Settling Kinetics
Authors: Pimpalkar Sarika Narayanrao , Suresh Nikkam , Singh Gurdeep
Published: March 2021

Settling tests were conducted on the washery effluent using three types of flocculants namely cationic (Telfloc-3674F), anionic (Magna-1011) and non-ionic (Nalco-83370 + ). For the study purpose coal washery effluent (having pH of 8.72) was collected from a newly commissioned plant-thickener. Tests were conducted by varying the pH of the pulp at three levels of acidic (4.0), alkaline (11.0) and the natural pH (8.72) of the as collected effluent, besides the flocculent dosages varied at four levels (2, 4, 6 and 8gpt) for each of the flocculants stated. The results of these tests, estimated in terms of initial settling rate and turbidity indicated that; among the three flocculants tested Telfloc-3674F and Magna-1011 gave best results as compared to Nalco-83370 + flocculent at a washery water pH 8.72. The effect of molecular weight of the flocculants on settling of solids in effluent has been established in terms of the kinetics with a characteristic number for each of the type of flocculants used.
Broadband Absorber Using Ultra-thin Plasmonic Metamaterials Nanostructure in the Visible and Near-Infrared Regions
Authors: Elrashidi Ali
Published: March 2021

In this work, an ultra-thin plasmonic metamaterial nanostructure absorber is simulated using finite difference time domain method in the visible and near infrared regions. A metamaterial, metal-insulator-metal, of a periodic structure of titanium-silica cap mounted on a top of a silver substrate covered by glass substrate is introduced in this paper. The glass substrate is used to enhance the absorption bandwidth by 276%, from 510 nm to 1410 nm. An almost perfect absorber, over 90% of the incident light, has been obtained for wavelengths from 440 nm to 1850 nm which produces an absorption bandwidth of 1410 nm. The square base unit cell dimensions of the silver substrate and of the cap are simulated and found as 250 nm and 200 nm consequently. The effect of using different materials for the top of the cap and for the insulator are also tested. The considered materials are titanium, nickel, silver, aluminum, and gold; however, the insulators are silica, quartz, vanadium dioxide, methyl methacrylate, and aluminium dioxide. In addition, aluminium, silver, copper, and gold are then simulated as a substrate metal. The optimum structure, which produce the maximum absorber bandwidth, 1410 nm, with a higher absorption, over 90%, is Glass-Ti-SiO2-Ag. Finally, the absorption bandwidth is calculated using different polarization angle, from 100 to 700 with a step100.
Two new Painlev´e integrable KdV–Calogero-Bogoyavlenskii-Schiff (KdV-CBS) equation and new negative-order KdV-CBS equation
Authors: Wazwaz Abdul-Majid
Published: March 2021

In this work, we develop two new (3+1)-dimensional KdV–Calogero-Bogoyavlenskii-Schiff (KdV-CBS) equation and (3+1)-dimensional negative-order KdV-CBS (nKdV-nCBS) equation. The newly developed equations pass the Painlev´e integrability test via examining the compatibility conditions for each developed model. We examine the dispersion relation and derive multiple soliton solutions for each new equation.
Clinical, Pathological and Radiologic Features of Minute Pulmonary Meningothelial-like Nodules
Authors: Wen Zhexu , Zhang Yang , Fu Fangqiu , Ma Zelin , Deng Chaoqiang , Ma Xiangyi , Hu Hong , Sun Yihua , Chen haiquan
Published: March 2021

Objectives: Reports about the radiologic features of minute pulmonary meningothelial-like nodules are sparse. This study aims to investigate the radiologic features of minute pulmonary meningothelial-like nodules. Method: From January 2016 to April 2019, 7589 patients underwent pulmonary resections at Fudan University Shanghai Cancer Center. Postoperative pathology records were reviewed retrospectively. Fifty-nine patients with minute pulmonary meningothelial-like nodule were included. The identification of minute pulmonary meningothelial-like nodules in pathology specimen included pathologically confirmed in resected nodules, and discovery in the peripheral tissue of other resected nodules incidentally. We went back and checked all the pre-operative scans of patients to analyze surgical decision and observe any change of visible minute pulmonary meningothelial-like nodule over time. Clinic, radiologic and pathological features were collected.Result: 59 patients included 10 men and 49 women, with a mean age of 57.7. 5 patients had history while 54 patients were non-smokers. 79 minute pulmonary meningothelial-like nodules was found. Of them, 36 nodules were not visible on computed tomography scan. 43 nodules were visible on computed tomography scan, with an average size of 5.3mm in 29 patients. Computed tomography appearance included pure ground-glass opacity in 36, mixed in 2 and solid nodules in 5. Nearly half of patients had a pre-operative follow-up more than 6 months (13/29, 44.8%). The median pre-operative radiologic follow-up was 4.9 months. Approximately 90% of patients underwent pulmonary surgery because of other malignant nodule on chest computed tomography scan (52/59, 88.1%). Conclusion: Most minute pulmonary meningothelial-like nodules tend to present as ground-glass opacity, especially pure ground-glass opacity. Continuous computed tomography monitoring revealed no radiologic change over time. Continuous computed tomography monitoring was necessary part of management of minute pulmonary meningothelial-like nodule.
Dynamic remodeling of presynaptic endoplasmic reticulum is coordinated through actin and microtubule crosstalk and contributes to defective stimulus-response in Spinal Muscular Atrophy
Authors: Sendtner Michael , Deng Chunchu , Moradi Mehri , Reinhard Sebastian , Doose Sören , Hennlein Luisa , Jablonka Sibylle , Sauer Markus
Published: March 2021

Background

Axonal degeneration and defects in neuromuscular neurotransmission represent a pathological hallmark in spinal muscular atrophy (SMA) and other forms of motoneuron disease. These pathological changes do not only base on altered axonal and presynaptic architecture, but also on alterations in dynamic movements of organelles and subcellular structures that are not necessarily reflected by static histopathological changes. In neurons, a highly dynamic endoplasmic reticulum (ER) network exists in the axonal and presynaptic compartment which regulates Ca2+ homeostasis and synapse maintenance. However, the mechanisms of its dynamic regulation and mechanisms of dysfunction that contribute to neurodegeneration remain elusive.

Methods

Using high resolution microscopy and life imaging of cultured motoneurons from wildtype and a mouse model of spinal muscular atrophy, we investigated the dynamics of the axonal endoplasmic reticulum and ribosome distribution and activation.

Results

These studies revealed that the dynamic remodeling of ER in axonal filopodia of cultured motoneurons depends mainly on actin cytoskeleton. In Smn -deficient motoneurons, movements of ER in filopodia seems to be more affected than in the growth cone core. In addition, ribosome assembly that happens within seconds after exposure to Brain derived neurotrophic factors (BDNF) is reduced in axon terminals of Smn -deficient motoneurons, and also the association with ER as a response to extracellular stimuli is highly disturbed.

Conclusions

These findings do not only define a novel function of presynaptic ER in dynamic regulation of local translation. They also implicate impaired dynamic movements of axonal and presynaptic ER as a contributor to the pathophysiology of SMA and possibly also other neurodegenerative diseases.
Toxicity effects of Ciprofloxacin on biochemical parameters, histological characteristics, and behaviors of Corbicula fluminea in different substrates
Authors: Guo Xiaoyu , Feng Chenghong , Bi Zhe , Islam Akhtar , Cai Yanpeng
Published: March 2021

Antibiotic toxicity and antibiotic resistance have become significant challenges to human health. However, the potential ecotoxicity of sediment-associated antibiotics remains unknown. In this study, the biochemical responses, histological changes, and behavioral responses of Corbicula fluminea (C. fluminea) exposed to sediment-associated ciprofloxacin (CIP) were systemically investigated. Special attention was paid to the influence of different substrate types. Biochemical analyses revealed that the balance of the antioxidant system was disrupted, eventually leading to oxidative damage to the gills and digestive gland with increasing CIP concentration. Severe histopathological changes appeared along with the oxidative damage. An enlargement of the tubule lumen and thinning of the epithelium in the digestive gland were observed under exposure to high CIP concentrations (0.5 and 2.5 µg/g CIP). In a behavioral assay, the siphoning of C. fluminea in the high concentration exposure groups was clearly inhibited. Moreover, from the integrated biomarker response (IBR) index, the toxicity response gradients of the digestive gland (no substrate–NOS > Sand > Sand and kaolinite clay– SKC > Sand, kaolinite clay, and organic matter–SCO) and gills (NOS > SCO > SKC > Sand) were different among substrate exposure groups. The most serious histopathological damage and highest siphoning inhibition were observed in the NOS group. The changes in the morphological structure of digestive gland cells in C. fluminea were similar in the other three substrate groups. The inhibition of the filtration rate in the higher concentration groups decreased in the order Sand > SKC > SCO.
Integrated Deep Auto-Encoder and Q-learning-based Deep Learning Scheme to detect anomalies from log data for supporting forensics in Cloud Computing
Authors: P Savaridassan , G. Maragatham
Published: March 2021

The cloud computing environment when deployed correctly is responsible for delivering scalability, cost efficiency, reliability, security and interoperability to the end users. Log analysis is considered to be an indispensable component of security regulations and framework, since these computer-generated records help the organizations, businesses and networks to respond to different kinds of risks that are possible to cloud environment in a reactive and proactive manner. In this paper, an Integrated Deep Auto-Encoder and Q-learning-based Deep Learning (IDEA-QLDL) Scheme is proposed for attaining maximum prediction accuracy during the process of exploring log data and classifying them into genuine and anomalous. It initiates the process of acceptance or denial based on the continuous investigation of behavioral patterns that are highly applicable for classification. The results of the proposed IDEA-QLDL Scheme confirmed its predominance in improving the classification accuracy, precision, recall and detection time compared to the benchmarked schemes considered for investigation.
Influence of natural discontinuities and mechanical properties on the fragmentation of marble by blasting in Central Africa
Authors: Njock Michel Constant , Meli’i Jorelle Larissa , Poufone Yvonne Koffi , Mbouombouo Ibrahim Ngapouth , Tamto Linda Well Have , Arétouyap Zakari , Manguelle-Dicoum Eliézer , Njandjock Philippe Nouck
Published: March 2021

This research focuses on the influence of natural discontinuities and mechanical properties in the fragmentation of marble by blasting. These natural discontinuities and mechanical properties are the parameters which are difficult to control and which considerably influence the fragmentation of marble after blasting. This paper aims at predicting the fragmentation of the Bidzar quarry rock, the only marble quarry in Central Africa, while improving the knowledge on it. This quarry has been facing problems of fragmentation of marble blocks for decades, which requires secondary firing and incurs enormous costs. The Kuz-Ram method was used for this study. The dip of the discontinuity planes, the compressive strength, the distance between the discontinuities and the density of the discontinuities are the operational parameters that were used to study the influence of natural discontinuities and the mechanical properties of the rocks on the fragmentation after firing. This work consists precisely in studying the pullability as a function of the dip of the discontinuity planes, then the fragmentation as a function of the powder factor, the compressive strength and the drilling mesh. The results of this study were compared with those of the other authors. Qualitative and quantitative studies were carried out in order to highlight the influence of natural discontinuities and mechanical characteristics on fragmentation. The fragmentation pattern of the Bidzar quarry was examined and compared with those obtained in other regions of the world, namely, Northern Europe, Central America, South-East Asia and West Africa. The variation in the intensity of fragmentation caused on the one hand by differences in the dips of the firing planes and their compressive strength, and on the other hand by the variation in the drilling mesh was also discussed. The prediction test was carried out with seven plans of existing discontinuities in the Bidzar quarry and at different mesh sizes in order to estimate the distribution of the fragments of marble thatcan through the crsuher after being fired. Several suggestions were put forward for the evaluation of the fragmentation. Three practical tables were created to predict the result of the shot. The specific graphs, which were proposed to analyse fragmentation in this quarry, made it possible to assess the quantity of fragments passing through the crusher after firing. Predicting fragmentation by considering the dip of the firing planes and the powder factor can effectively optimise the fragmentation of the rocks by blasting and achieve the desired result.
Assessing the relationship between public spending and economic growth through an endogenous growth model
Authors: Gnangoin Thierry Y. , Du Liangsheng
Published: March 2021

Public spending is a part of the fiscal policy and one of the government’s main tools to implement its economic policy. With government spending still on the rise in many economies, and the different economic growth levels, especially in low and middle economies, the debate on whether government spending has a positive, negative or neutral impact on economic growth is still raging nowadays. So, in this analysis, we attempt to contribute to this issue by shedding light on this relationship in the case of low, middle, and high-income countries. In so doing, we extend the previous work of Devarajan et al. (1996) and Chu et al. (2020) by considering the nonlinear relationship between disaggregated public spending and economic growth. We also pay attention to the role of public spending on environmental protection, political stability, control of corruption, and the 2008 financial crisis, on economic growth. To reach our objectives, we examine 13 high-income countries and 22 low to middle-income countries for the period 1993–2018 through four estimations techniques: the fixed-effects approach; the pooled standard errors Driscoll-Kraay (1998), the panel feasible generalized least squares, and the difference GMM with orthogonal deviations.
Rest Profoundly Protects Against Cardiac Remodeling and Benefits Repair
Authors: Martino Tami , Reitz Cristine , Alibhai Faisal , Khatua Tarak , Pyle W. Glen
Published: March 2021

Cardiovascular disease is a leading cause of morbidity and mortality worldwide1. Although rest has long been considered beneficial to patients2, remarkably there are no evidence-based experimental models determining how it benefits disease outcomes. Here, we create a novel experimental rest model in mice, whereby light-induced manipulation of the circadian system briefly extends the rest period by 4 hours each morning. We found, in two different cardiovascular disease conditions (cardiac hypertrophy, myocardial infarction), that imposing a short, extended period of rest each day persistently reduces cardiac remodeling, as compared to control mice subjected to only normal periods of rest, supporting the therapeutic benefits of rest to slow functional decompensation in heart disease. Mechanistically, rest reduces hemodynamic stress on the cardiovascular system, imposing changes on myofilament contractile function in the heart independently consistent within each disease phenotype. Molecular analyses reveal attenuation of cardiac remodeling genes, consistent with the benefits on cardiac structure and function. These same cardiac remodeling genes underlie the pathophysiology of many major human cardiovascular conditions, as demonstrated by interrogating open-source transcriptomic data, and thus patients with other conditions may also benefit from a morning rest period in a similar manner. In summary, we report that rest is a key driver of physiology, leading to the development of an entirely new field on the nature of rest, and provide a strong rationale for advancement of rest based therapy for major clinical diseases.
Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction
Authors: Fan Tianfei , Hou Yangfeng , Ge Weipeng , Fan Tianhui , Guo Wenjun , Song Xiaomin , Gao Ran , Wang Jing
Published: March 2021

Hypertension is a common chronic disease, which leads to cardiovascular and cerebrovascular diseases, and its prevalence is increasing. Cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) pathway participates in multiple cardiovascular diseases. Phosphodiesterase (PDE) 4 has been shown to regulate PKA activity via cAMP specific hydrolysis. However, whether PDE4-cAMP-PKA pathway influences hypertension remains unknown. Herein, we reveal that PDE4D (one of PDE4 isoforms) expression is upregulated in angiotensin II (Ang II)-induced hypertensive mice aortas. Furthermore, knockout of Pde4d in mouse smooth muscle cells (SMCs) attenuate Ang II-induced high BP, arterial wall media thickening, vascular fibrosis and vasocontraction. Upon further investigation, we find that Pde4d deficiency activate PKA-AMP-activated protein kinase signaling pathway to inhibit myosin phosphatase targeting subunit 1-myosin light chain phosphorylation, relieving Ang II-induced SMC contraction in vitro and in vivo. These results indicate that PDE4D may be a potential target for hypertension therapy.
Vitamins D2 and D3 have overlapping but different effects on human gene expression revealed through analysis of blood transcriptomes in a randomised double-blind placebo-controlled food-fortification trial
Authors: Durrant Louise , Bucca Giselda , Hesketh Andrew , Moller-Levet Carla , Tripkovic Laura , Wu Huihai , Hart Kathryn , Mathers John , Elliott Ruan , Lanham-New Susan , Smith Colin
Published: March 2021

For the first time we report the relative influences of vitamin D2 and vitamin D3 on genome-wide gene expression in whole blood from healthy women, representing two ethnic groups, white European and South Asian. In this randomised placebo-controlled trial, participants were given daily physiological doses (15 µg) of either vitamin D2 or D3 for 12 weeks and changes in the transcriptome were compared relative to the transcriptome at baseline. While there was some overlap in the repertoire of differentially expressed genes after supplementation with each vitamin D source, most changes were specific to either vitamin D3 or vitamin D2, suggesting that each form of the vitamin may have different effects on human physiology. Notably, following vitamin D3 supplementation, the majority of changes in gene expression reflected a down-regulation in the activity of genes, many encoding components of the innate and adaptive immune systems. These are consistent with the emerging concept that vitamin D orchestrates a shift in the immune system towards a more tolerogenic status. Moreover, gene expression associated with type 1 and type 2 interferon activity differed following supplementation with either vitamin D2 or vitamin D3, with only vitamin D3 having a stimulatory effect. Interferons play a critical role in the innate response to infection and aberrant type 1 interferon signalling has recently been implicated in severe Covid-19 disease. The observed differences in gene expression after supplementation with vitamin D2 compared with vitamin D3 warrant a more intensive investigation of the biological effects of the two forms of vitamin D on human physiology.
Determinants of Dietary Practice among Type 2 Diabetic Patients: Institution based cross-sectional study
Authors: Desta Derese Tamiru , Michael Mignote Gebre , Hailu Dejene , Zegeye Menen
Published: March 2021

Objectives

Dietary management is considered to be one of the cornerstones of diabetes care. There is a lack of data on the dietary practice of diabetic patients, which underestimates its role in the management of diabetes. Hence, this study assessed the level of dietary practices and their associated factors among Type2 diabetic patients in Hawassa city, Sidama Region, Ethiopia.
Results

Nearly forty-seven percent (46.8%) of the patients had poor knowledge about diabetes. More than half of the respondents (54.5%) were overweight and obese. The levels of dietary practice among 171 (44.2%) type 2 diabetic patients were poor. Very low monthly income [AOR = 4.87; 95% CI :(1.20-19.81], taking insulin regimen [AOR = 2.36; 95% CI :(1.13–4.91)], taking both insulin injection and oral medication [AOR = 11.26; 95% CI: (3.05–41.54)], not getting DM education in hospital [AOR = 2.72; 95% CI :( 1.08–6.85)], despondency [AOR = 3.71; 95% CI:(1.39–9.89), lack of support from family and friends about dietary plan [AOR = 5.64;95% CI (2.66,11.92)], unavailability of fruits and vegetables[AOR = 3.04;95% CI:(1.11–8.34)] were the factors significantly associated with the poor dietary practice.
Reuse of improved recycled concrete aggregates (RCA) for sustainable and environmental-friendly construction materials.
Authors: Alyaseen Ahmad Sarhan , Shah Siddharth , Solanki Ravindra , Daxini Bhavik , Alwani Yogesh K. , Alahmad Hussain
Published: March 2021

Recycled aggregates have an essential role in constructing construction activities today to save natural aggregates because of industrial development. The research aims to assess the suitability of recycled aggregates for the construction of new roads, which will help achieve road construction efficiency and help prevent environmental deterioration in the extraction and reducing pollution. In contrast with natural aggregates, recycled aggregates are of lower quality, mainly due to the cement mortar's brittle nature attached to them. The point of the study is to increase the performance of RCAs in an environmentally friendly managing RCAs. In this process, RCAs are first soaked in acetic acid solution, in which acetic acid reacts with cement attached to the surface of the RCA. This reaction weakens the attached mortar and allows separating from the RCAs by using mechanical friction later. Treated RCAs have lower water absorption and more insufficient cement mortar adhesion. These RCAs used as aggregates in new the concrete increased the compressive strength, the tensile strength, and the concrete's flexural strength by 26%, 11%, and 26% at 28 days, respectively. It is clean, safe, efficient, and a new method to be applied, so no harmful products are used, and no dangerous substances are incorporated into the RCAs that are being treated. The waste treatment solution was used as a supplementary admixture construction, increasing the concrete's strength, and decreasing its environmental effects.
Clinical and Healthcare Improvement through My Health Record usage and Education in General Practice (CHIME-GP): A study protocol for a cluster-randomised controlled trial
Authors: Bonney Andrew , Metusela Christine , Mullan Judy , Barnett Stephen , Rhee Joel , Kobel Conrad , Batterham Marijka
Published: March 2021

Background: There is international interest in whether improved primary care can lead to a more rational use of health resources and whether the use of a national digital health record system by primary health care professionals can help achieve this goal. This trial (CHIME-GP) will investigate whether a multifaceted education intervention in an Australian general practice setting on the use of a national digital health record system leads to reductions in health-service utilisation and costs.Methods: The trial will be undertaken in Australian general practices. The aim of the research is to evaluate the effectiveness of a web-based educational intervention for general practitioners, regarding use of a national digital health record system, My Health Record (MHR), and rational use of medicines, pathology and imaging. Our target is to recruit 120 general practitioners from urban and regional regions across Australia. We will use a mixed methods approach incorporating a three-arm pragmatic cluster randomised parallel trial and a prospective qualitative inquiry. The effect of the intervention in each arm will be assessed, using the other two arms as controls. The evaluation will synthesise the results embedding qualitative pre/post interviews in the quantitative results to investigate implementation of the intervention, clinical behaviour change and mechanisms such as attitudes, that may influence change. The primary outcome will be an economic analysis of the cost per 100 consultations of selected prescriptions, pathology and radiology test ordering in the six months following the intervention compared with six months prior to the intervention. Secondary outcome measures include the rates per 100 consultations of selected prescriptions, pathology and radiology test ordering six months pre and post intervention; and comparison of knowledge assessment tests pre and post intervention.Discussion: The trial will produce robust health economic analyses on the evidence on educational intervention in reducing unnecessary prescribing, pathology and imaging ordering, and in improving the use of MHR. In addition, the study will contribute to the evidence-base concerning the implementation of interventions to improve the quality of care in primary care practice.Trial registration: Australian New Zealand Clinical Trials Registry ACTRN12620000010998. Registered on 09 January 2020.http://www.ANZCTR.org.au/ACTRN12620000010998.aspx
Chiral magnetism: a geometric perspective
Authors: Hill Daniel , Slastikov Valeriy , Tchernyshyov Oleg
Published: March 2021

We discuss a geometric perspective on chiral ferromagnetism. Much like gravity becomes the effect of spacetime curvature in theory of relativity, the Dzyaloshinski-Moriya interaction arises in a Heisenberg model with nontrivial spin parallel transport. The Dzyaloshinskii-Moriya vectors serve as a background SO(3) gauge field. In 2 spatial dimensions, the model is partly solvable when an applied magnetic field matches the gauge curvature. At this special point, solutions to the Bogomolny equation are exact excited states of the model. We construct a variational ground state in the form of a skyrmion crystal and confirm its viability by Monte Carlo simulations. The geometric perspective offers insights into important problems in magnetism, e.g., conservation of spin current in the presence of chiral interactions.
Reconciling Locality and Globalization through Sense of Planet in Kiana Davenport’s the House of Many Gods
Authors:   Universitas Gadjah Mada, Indonesia., Indriyanto Kristiawan
Published: March 2021

This study positions the House of Many Gods, a novel written by Kiana Davenport as a possible area of intersection between globalization and environmental/eco-criticism. The primacy of locality within American environmental discourse hinders the acceptance of global theory under the assumption that embracing the global will lead into the erasure of the local altogether. In her book, Sense of Place and Sense of Planet (2008) Ursula K Heise asserts that what she considers as sense of place is incomplete without considering ourselves as a part of a global ecosystem, which she considers as sense of planet. The reading of the House of Many Gods contextualizes sense of place and sense of planet through the perspective of Ana, in which she complements her adherence of Native Hawai’ian epistemology of place with a broader outlook of environmental crisis. A global outlook of perceiving environmentalism also aligns with Transnational American Studies which perceives America from an internationalist perspective. The paper concludes that sense of place and sense of planet provides a possible intersectionality of conceptualizing local discourse of place within a global outlook of environmentalism.
Age, Feeling and Experience Framing a Modernist Vision in Panait Istrati’s Stavro
Authors:   Bucharest University of Economic Studies. Faculty of International Business & Economics, Radler Dana
Published: March 2021

In Stavro, the first opening piece of Kyra Kyralina (published in 1923), the narrative focuses on the actions taken and the reactions shown or concealed by three male characters in alternation, with particular emphasis on gender, age, and experience. In between traditionally built sections and ample back-storytelling, the story addresses the key learning stances adopted by the three male characters at the end of a short trip that they complete together: reserve, reclusion and (self-)reflection. How does a modernist vision frame one’s identity against age, common social norms and openly manifested repression in small urban neighbourhoods? Can one protagonist’s understanding about his sexual orientation be genuinely shared with others? In what way does Stavro’s personal experience alienate his prospects of family life in the port of Br?ila? This paper aims to decode the narrative based on modern confession, continuity versus fragmentation, sexuality and modes of memory alter(n)ation.
Gendered Parenting influence on Children’s Socialization to Gender Stereotype in Marital life
Authors:   School of Humanities, KIIT Deemed to be University, Bhubaneswar, India, Dulla Nisrutha , Priyadarshini Sugyanta
Published: March 2021

This research work draws attention towards heated debate on transfer of gender biased ideology to generations embedding from gendered parenting. Gendered parenting has the potential to be a breeding ground for fueling the belief of gender stereotyping in the minds of their offsprings. This notion of gender stereotyping has created a picture in the heads of the descendants regarding the fixed gender roles which develops gendered socialization in governing the social world from the lens of gender biasness. The objective of the study is to examine empirically the impact of gendered parenting on gendered socialization in their children’s marital life. The study adopts thirty-two-items scale devised by Brogan & Kutner (1976) and eight- items scale under Gender Role Stereotype Scale (2012) by taking into consideration a sample size of eight hundred respondents comprising of highly educated married professionals and their parents. The findings revealed that children have rightly perceived their parent’s act of gender stereotype in their childhood. Consequently, despite being highly educated, the act of gender stereotyping continues in their married life as they burgeoned under the reflection of gendered parenting. Furthermore, it is also interpreted in the analysis that the female respondents are adversely affected by the pervasive bias and prejudices of gender stereotype in professional life in comparison to the male respondents. The study makes efforts to enhance the understanding of the community of parents to limit the transmission of gendered ideology to their next generations, thereby, progressing towards egalitarian society.
Non-Verbal Signs and Secret Communication as Universal Signs of Intercultural Communication
Authors:   Buketov Karaganda University, Ulitsa Universitatskaja, 28, Karaganda, Kazakhstan, Muratova Altyn N. , Mazhitayeva Shara , Sarybayeva Bayan Zh. , Kelmaganbetova Aiman , Kulibekova Zhanar
Published: March 2021

The article is devoted to the study of the national cognitive nature, the hidden essence of non-verbal techniques. The main purpose of the study is to prove that, based on materials on nonverbal uses in language, they are used to convey a confidential, hidden message, to show that in international communication there is a change in the semantics of nonverbal actions depending on the culture and individual knowledge of each nation. Methods In human life, in parallel with verbal communication, an experiment was conducted on nonverbal techniques, sometimes used in pure form and used to convey a secret and hidden message. The article presents an analysis based on a statistical method compared with some kinemes used in a common language. In the studies on non-verbal techniques, it is noted that they perform a main function in the relations between people. In this article, in the course of analyzing the nature of nonverbal techniques, we characterized some kinemes used depending on the worldview of the Kazakh people, and concluded that their background is directly related to the mystery. Application of the study: the results, materials, and conclusions of the work can be used in the history of language, sociolinguistics, and paralinguistic studies, and allow researchers of gesture semantics to explore nonverbal techniques from a new perspective. Scientists-linguists, psychologists have created many works related to the definition of human nature, character, and the place of nonverbal techniques in the speech act. However, it was not said that auxiliary means located outside the language will be used to transmit confidential, non-public information. In this work, we stopped at the place of nonverbal methods of transmitting confidential, hidden information and analyzed the functions in confidential communication.
The audience and the star: Genre as the interface and expectation-fulfillment as the catalyst of their relationship
Authors:   Department of Media Studies and Journalism, University of Liberal Arts Bangladesh (ULAB)., Bhowmick Bikash Ch.
Published: March 2021

This article explores the relationship between a film audience and a film star. It assumes that the genre is a common ground or interface where an actor – who then becomes the star, and an audience meet together and afterward the expectations of that audience become the key player to push forward the relationship between them. In forging the relationship between two parties, the genre takes the responsibility of constructing an actor’s star-personality and of shaping the spectator’s size of a distinct kind. To substantiate the argument, the essay discusses audiences’ inscribed entity and construction of a star under the title ‘the star – a construction of the negotiations’; the dynamics of their relationship under the title ‘audience expectation and their relationship with the Star’ and finally, in conclusion, it highlights the genre’s intermediary contribution to the relationship. The author has taken the critical/theoretical approach; therefore heavily relied on existing literature and theories (e.g. psychoanalysis, star theory). Primary data has also been used in support of the arguments. Survey questionnaires and in-depth interviews have been used as methods of primary data collection.
The Cultural Expressions and Representation of National Identity- A Study of the Indian Singing Reality Television Show “Sa Re Ga Ma Pa”
Authors:   Department of Journalism and Mass Communication, Manipal University Jaipur, Rajasthan-India, Chawla Taranjeet Kaur , Sharma Shiv Shankar , Hassan Rayaz
Published: March 2021

This paper aims to understand the narrative structure of Indian singing reality television show to identify the representation of national identity. By focusing on the “Sa Re Ga Ma Pa” show format, this paper has followed the work of Vladimir Propp to examine the cultural expressions with the sequential development of the narrative plot. The convergent parallel mixed method has been using to collect quantitative and qualitative data. While using the Likert scale, the reliability of the questionnaire has been calculated and reported Cronbach’s alpha coefficient for internal consistency reliability. The quantitative data has gathered from 205 respondents and 99 episodes aired from 2017 to 2019 have analysed in qualitative data, which is followed by data analysis through IBM SPSS Statistics. By analysing the quantitative and qualitative data this paper finds that the cultural expressions reveal the notion of national identity through the representation of ‘ordinary’ people and emphasis on performances by focusing on the structured format of Indian reality television. The paper indicates the ways where the viewers of the society can connect with cultural expressions through the genre of reality television.
Prevalence of water-borne diseases in western India: dependency on the quality of potable water and personal hygiene practices
Authors: Karande Koustubh , Tandon Shalini , Vijay Ritesh , Khanna Sunali , Banerji Tuhin , Sontakke Yeshwant
Published: March 2021

Unlike urban and semi-urban settlements where the potable water is supplied through a water treatment plant and a distribution network, in rural low-income settings, the provision of the water treatment plant for all villages is not feasible for a developing country like India. The most affordable and reliable way to provide clean drinking water is treatment at the consumer end. This research is aimed to assess occurrence of water-borne diseases based on personal hygiene and quality of drinking water source. Of the households, 4,237 in 15 selected villages were surveyed for personal hygiene using a questionnaire. Water samples were collected from all major water sources in the villages and analyzed for chemical and bacteriological properties. For water and personal hygiene, quality indices were calculated, and a mathematical model was developed using multiple linear regression analysis. The regression concluded that personal hygiene has a more significant effect on the occurrence of water-borne diseases than the quality of water source in the study area. Personal hygiene is one of the health factors neglected by the people specifically in rural India. Therefore, India needs to run campaigns like Swachh Bharat Abhiyaan (Clean India Mission), which mainly aimed to reduce open defecation, to promote personal hygiene and to reduce the prevalence of water-borne diseases.
Adsorptive removal of P(V) and Cr(VI) by calcined Zn-Al-Fe ternary LDHs
Authors: Rezak Nacera , Bahmani Abdellah , Bettahar Nourredine
Published: March 2021

The present study deals with the preparation and structural and adsorbent characterization of the ternary layered double hydroxides (LDHs; ZFA-HT) with molar ratio Zn2+/Al3+/Fe3+ = 2/0.5/0.5 and its product calcined (ZFA-350) at 350 °C, which is examined for the removal of phosphate P(V) and chromate Cr(VI) from aqueous media. The as-obtained materials are characterized by X-ray diffraction (XRD), Fourier-transform infrared (FT-IR), thermogravimetric analysis-differential scanning calorimetry (TGA–DSC), scanning electron microscopy-X-ray energy dispersion (SEM-EDX) and Brunauer–Emmett–Teller (BET). Structural characterizations show that the LDHs is successfully synthesized and its calcined product is a mixed oxide. Batch sorption studies are conducted to investigate the effects of various experimental parameters such as contact time, solution pH, adsorbent amount, initial P(V) or Cr(VI) concentration and temperature. The isotherms, kinetics and thermodynamic parameters of adsorption of phosphate and chromium are studied. The adsorption processes are well described by the pseudo-second-order kinetic model than the other models examined. The adsorption isotherms data fit best to the Langmuir isotherm model instead of Freundlich and Dubinin–Radushkevich models. The maximum monolayer adsorption capacity of ZFA-350 was found to be 140.85 mg/g for P(V) and 52.63 mg/g for Cr(VI). The positive ΔH and ΔS and negative ΔG values reveal that the P(V) and Cr(VI) sorption onto ZFA-350 is endothermic, irreversible and spontaneous in nature.
Energy Transition Investments and Financing Instruments
Authors: Bahtizina N. V. , Bahtizin A. R.
Published: March 2021

International organizations representing the interests of energy-deficient developed countries are urging to solve the problem of global warming through the Energy Transition, which implies decarbonization of the world economy. The implementation of the Energy Transition requires annual investments of 3% of world GDP in energy efficiency, renewable energy, electric vehicles, etc. In 2020, despite the acceleration of dynamics, the volume of world investments was more than 5 times lower than required. The leaders in investments in clean energy are the technologically developed countries of Europe, the USA, Japan, as well as developing countries – China and Brazil, striving for technological independence. In order to expand its presence in the promising market for low carbon technologies, the EU pays special  attention  to  innovations  in  the  field  of  clean  energy,  financing  them  through  the Innovation Fund. To prevent Russia’s technological backwardness and reduce the carbon footprint of export products, it is advisable to envisage the possibility of state support for innovative projects in the field of clean energy from the Climate Fund.
Constitutional Changes and a New Stage of Russian Federalism Development
Authors: Bukhvald E. M.
Published: March 2021

The  amendments  and  additions  to  the  Constitution  of  the  Russian  Federation  of  1993, approved by popular vote, should be considered as the significant advance in the development of the legal foundations of the Russian state, including a wide range of issues, related to the Russian model of federalism and its implementation in the practice of state and municipal administration. These changes can hardly be regarded as one of the stages of the federal reform, especially since the final goals of this reform were not clearly stated earlier and even now remain very uncertain. Nevertheless, as it’s shown in the article, some of these changes can have a significant impact on the nature and mechanism of functioning of the Russian federal state, in particular, on the activities of state and municipal government bodies. The article suggests that constitutional changes and additions in 2020 can significantly strengthen the  democratic  and  social  nature  of  the  state.  At  the  same  time,  it’s  argued  that  these changes should not be given the status of “finiteness”. It is obvious that the federal reform in the country, no matter how it is regarded, has not exhausted its potential, which in the foreseeable future may give an impetus to the further development of the legal foundations of Russian federalism, including the sphere of its constitutional regulation.