bluuebunny/crossref_metadata_2025 huggingface dataset:
New Exponential Ratio Estimator in Ranked Set Sampling
Authors: Khalid Rather , KOÇYİĞİT Eda Gizem , ÜNAL Ceren
Published: June 2022

In this study, we adapted the families of estimators from Ünal and Kadilar (2021)  using the exponential function for the population mean in case of non-response for simple random sampling for the estimation of the mean of the population with the RSS (ranked set sampling) method. The equations for the MSE and the bias of the adapted estimators are obtained for RSS and it in theory shows that the proposed estimator is additional efficient than the present RSS mean estimators in the literature. In addition, we support these theoretical results with real COVID-19 real data and conjointly the simulation studies with different distributions and parameters. As a result of the study, it was observed that the efficiency of the proposed estimator was better than the other estimators.
A New Flexible Probability Model: Theory, Estimation and Modeling Bimodal Left Skewed Data
Authors: Aboraya Mohamed , Ali M. Masoom , M. Yousof Haitham , Mohamed Mohamed Ibrahim
Published: June 2022

In this work, we introduced a new three-parameter Nadarajah-Haghighi model. We derived explicit expressions for some of it statistical properties. The Farlie Gumbel Morgenstern, modified Farlie Gumbel Morgenstern, Clayton, Renyi and Ali-Mikhail-Haq copulas are used for deriving some bivariate type extensions. We consider maximum likelihood, Cramér-von-Mises, ordinary least squares, whighted least squares, Anderson Darling, right tail Anderson Darling and left tail Anderson Darling estimation procedures to estimate the unknown model parameters. Simulation study for comparing estimation methods is performed. An application for comparing methods as also presented. The maximum likelihood estimation method is the best method. However, the other methods performed well. Another application for comparing the competitive models is investigated.
Spatial-temporal factors affecting monthly rainfall in some Central Asian countries assuming a Weibull regression model
Authors: Barili Emerson , Achcar Jorge Alberto , Oliveira Ricardo Puziol de
Published: June 2022

Climate change has been observed worldwide in the last years. Among the different effects of climate change, rain precipitation is one of the effects that most challenge the population of all countries in the world. The main goal of this study is to introduce a data analysis of monthly rainfall data related to five countries in Central Asia (Kazakhstan, Kyrgyzstan, Tadjikistan, Turkmenistan and Uzbekistan) for a long period of time to discover the behavior of rain precipitation in these countries in the last decades and possible link with climate change. Since climate data are positive real values, Weibull regression models are used in the data analysis in presence of some spatial factors  as latitude and longitude of the climate stations in each country, temporal factors (linear year effects), altitude of the climate station and categorical factors (countries).The obtained results show that some factors have different effects in the monthly rainfall of the assumed countries during the follow-up assumed period, possibly linked to the climate change observed in the last decades worldwide.
Ecos del trauma en la banda sonora cinematográfica. La música y el melodrama cinematográfico griego de los sesenta
Authors: Poulakis Nick
Published: June 2022

Grandes crisis traumáticas, como la Catástrofe de Asia Menor (1922) y el desarraigo forzoso de más de 1,5 millones de griegos de sus países de origen al continente griego por parte de los turcos, se han mostrado en numerosas películas populares del llamado “Cine Griego Antiguo” de los años sesenta. Como parte de esa realidad se encuentra Klak Film, una productora de películas de serie B especializada en melodramas de culto de bajo presupuesto, protagonizados por Nikos Xanthopoulos –un actor muy querido y cantante famoso–, algunos de los cuales hacen referencia al desastre mencionado. Estas películas reproducen la percepción griega popularizada de la controversia cultural entre Oriente y Occidente al formar una imagen musical y fílmica épica construida sobre generalizaciones conceptuales y representaciones ingenuas del pasado a través de la memoria popular/nacional de traumas colectivos. El artículo presenta la producción de Klak Film La Odisea de un Hombre Desarraigado con un enfoque particular en su música como un ejemplo de nostalgia nacionalista que se hace ecos de episodios traumáticos anteriores, pero también de las ansiedades e inconvenientes del presente.
Detalles del artículo
“Utopias brasilienses” en la música vocal preexistente del documental Brasília: contradições de uma cidade nova
Authors: Céspedes Gómez Ivette
Published: June 2022

El documental Brasília, contradições de uma cidade nova (1967), del cinema novista Joaquim Pedro de Andrade, fue uno de los materiales que emprendió la cartografía poética y crítica de la recién inaugurada capital de Brasil. Se pretende demostrar cómo el realizador reforzó el cuestionamiento a las “utopías brasilienses” valiéndose de la música preexistente. Para ello, se analiza la música vocal preexistente a partir de tres ejes principales: la monumentalidad de Invocação à patria de Heitor Villa-Lobos como irónica exageración de la “alegoría a la patria”; la desilusión avisada en el cantar amateur de A banda de Chico Buarque y la propuesta de una “utopía de la resistencia” en la interpretación Viramundo de Maria Bethânia. Las músicas preexistentes completan el gesto crítico a la utopía modernista brasiliense que falsificó la vida real de esta ciudad escindida entre el “plano piloto” y las “ciudades satélites”.
Elaboración de suites de música cinematográfica en concierto. Musimagen y su comisión permanente
Authors: Román Alejandro
Published: June 2022

Desde hace años los conciertos de música de cine son cada vez más habituales, programándose partituras, tanto de películas, como de series de televisión o videojuegos. Los clásicos “conciertos de bandas sonoras” de los auditorios de música se amplían a festivales y congresos de música de cine, cada vez más numerosos. Para ello es preciso reconvertir las partituras empleadas en las grabaciones en obras destinadas al concierto. Musimagen, a través de su comisión permanente, elabora anualmente suites de la música de sus socios, contando en la actualidad con un catálogo de sesenta bandas sonoras. Todo ello necesita de un proceso de selección, reorquestación y edición y preparación de particellas que haga posible su puesta a disposición de las orquestas. El catálogo publicado cuenta tanto con suites para orquesta como para banda sinfónica, así como “suites históricas”. Se presentan aquí los criterios para su elaboración, así como los canales para su difusión.
Detalles del artículo
Estruendo y pesadilla en la miniserie DEVS
Authors: Malmierca Hernández Ana , Martínez Martínez Yolanda
Published: June 2022

El material sonoro creado para la miniserie DEVS es un ejemplo singular, dentro de la extraordinaria profusión del formato al que estamos asistiendo recientemente. En DEVS el relato audiovisual cabalga sobre elementos visuales y musicales particulares, que tejen una atmósfera densa y perturbadora. La introducción de chirridos metálicos (avanzamos sobre raíles), como de una pesada y antigua máquina sin engrasar refuerza la idea de predestinación, mientras que el estruendo de unos altavoces al máximo de su volumen se utiliza para generar un entorno de zozobra y pesadilla que envuelve a los personajes. El uso de la música religiosa junto con acordes superpuestos de saxofón resalta la fascinación por la ciencia y a la vez alerta ante el fanatismo sectario y amenazante de los trabajadores de DEVS.
Ruptura narrativa y discurso musical en Rick y Morty. Una aproximación a la música en la animación para adultos
Authors: Matas de Íscar Irene , Pérez Borrajo Aarón
Published: June 2022

Rick y Morty es una serie de animación para adultos emitida por primera vez en Adult Swim en 2013. La trama se centra en las aventuras de un científico, Rick Sanchez, quien viaja por el tiempo y el espacio acompañado de su nieto Morty. Su originalidad radica en los continuos juegos narrativos basados en teorías filosóficas y científicas a las que los protagonistas aluden constantemente, mezclándolas con elementos de la cultura pop. En este artículo partimos de la siguiente pregunta: ¿Cómo afectan las novedades impuestas en el desarrollo de la historia al discurso musical? Tras una contextualización histórica de la serie de animación, realizamos un análisis de la música preexistente del que se extraen dos conclusiones principales: su inclusión en la trama es fundamental para la evolución narrativa, y la canción preexistente se utiliza como leitmotiv. En este sentido, Rick y Morty aporta nuevas visiones para la creación de series de animación, estableciéndose como un referente dentro de la actual edad de oro de la ficción seriada.
Música y cine en tiempos de pandemia: la reutilización de músicas en La voz humana (2020) de Pedro Almodóvar
Authors: Jiménez Arévalo Alberto
Published: June 2022

La industria del cine es uno de los sectores audiovisuales más afectados por los efectos del coronavirus. La pandemia ha cerrado las salas de cine, ha suspendido estrenos y ha paralizado rodajes. En este artículo nuestro objetivo es entender la repercusión de la pandemia en los productos cinematográficos poniendo el foco de atención en su música. En estos tiempos excepcionales que vivimos, el cineasta Pedro Almodóvar rueda y estrena La voz humana (2020), cortometraje que adapta libremente el monólogo homónimo de Jean Cocteau (1930), con el que ha apostado por mantener el modelo tradicional de consumo de cine en las salas de proyección a precio reducido. Analizaremos la música del compositor Alberto Iglesias para La voz humana para entender cómo se reciclan varios temas musicales preexistentes de los filmes Hable con ella (2002), Los abrazos rotos (2009) y La piel que habito (2011). Por último, hemos establecido los diálogos intertextuales que se entablan en la música como consecuencia de su “recontextualización” en el nuevo cortometraje en el marco de la pandemia.
Marcos Ramos, M. (Coord.) (2021). Joyas escogidas. Pequeñas (pero grandes) películas en español y en portugués. Madrid: Dykinson, 168 pp. ISBN: 978-84-1377-933-1
Authors: Benito Blanco Javier
Published: June 2022

Reseña de libro
Uma revisão sistemática sobre as abordagens e métodos utilizados no zoneamento ecológico-econômico no Brasil
Authors: Arantes Leticia Tondato , Silva Darllan Collins da Cunha e , Lourenço Roberto Wagner
Published: June 2022

O zoneamento ecológico-econômico é caracterizado como um instrumento estratégico para o desenvolvimento de sistemas de planejamento e gestão de espaços territoriais, possibilitando o desenvolvimento em bases sustentáveis. O objetivo deste estudo foi identificar os métodos utilizados para a elaboração de um zoneamento ecológico-econômico e o atual estado de investigação científica no Brasil, por meio de uma revisão bibliométrica sistemática. Durante a pesquisa foi estabelecida a palavra-chave denominada “zoneamento ecológico-econômico” para realizar o processo de busca, obtendo-se um conjunto de 13 artigos. Com base nos resultados, foi possível constatar que são vários os parâmetros e zonas de manejo utilizadas para a elaboração do ZEE, variando em função de aspectos como as características da área, normas e diretrizes regionais e o objetivo do gestor. Por fim, nota-se que pesquisas acerca desse tema ainda são incipientes, indicando um campo de conhecimento com muitas oportunidades e desafios.
O núcleo de estudos sobre gênero de um Instituto Federal do Rio Grande do Sul: um espaço de resistência na Educação Profissional e Tecnológica
Authors: Fioravanti Tábata Dos Santos , Brancher Vantoir Roberto
Published: June 2022

O objetivo deste artigo é apresentar um estudo sobre os núcleos de estudo sobre gênero de um Instituto Federal do Rio Grande do Sul, pesquisar suas ações e acolhidas e identificar desafios e potencialidades para a existência desses núcleos. Trata-se de uma pesquisa qualitativa, com a coleta de dados realizada por entrevistas semiestruturadas. As discussões foram produzidas à luz da análise de conteúdo. Os resultados apontam que o Núcleo mais antigo é de 2016. As entrevistadas demonstram desconhecer o ato de criação do núcleo, porém isso não impede que as ações dos núcleos ocorram. As atuações dos núcleos condizem com o objetivo de formação humana e integral dos Institutos Federais. Os desafios apontados são referentes à ausência de sala e de orçamento, porém o núcleo foi exaltado como espaço de acolhida e segurança. As importâncias do núcleo destacadas ressaltam que esses espaços devem ser fortalecidos pelas gestões e comunidade geral.
Exigência dietética de fósforo na alimentação por fases da tilápia do Nilo
Authors: Quintero-Pinto Luis Gabriel , Pezzato Luiz Edivaldo , Pardo-Gamboa Blanca Stela , Padilha Pedro De Magalhães , Araujo Daniel De Magalhães
Published: June 2022

O fósforo possui diversas funções biológicas, estando relacionado desde a formação óssea até o fluxo de energia, assim como possui relação direta com as questões ambientais, já que nitrogênio e fósforo são os principais responsáveis pela eutrofização de efluentes da aquicultura. Dietas que atendam às exigências nutricionais para cada fase de vida dos peixes podem contribuir para a melhoria do desempenho zootécnico e para o meio ambiente. Os estudos foram realizados para determinar as exigências de fósforo disponível para tilápias do Nilo em três faixas de peso (Fase I: 16 g – 100 g; Fase II: 38 g – 250 g e Fase III: 155 g – 350 g). Para isto, rações isonutricionais foram formuladas com cinco níveis crescentes de fósforo disponível para cada ensaio independente. Os peixes foram criados em sistemas de recirculação (tanques com 90 L, 250 L e 250 L) com filtragem físico-biológica durante 60 dias para determinar desempenho zootécnico, parâmetros fisiológicos e mineralização corporal. As exigências nutricionais de fósforo disponível para os peixes de 16 g – 100 g, 38 g – 250 g e 155 g – 350 g foram: 0,76%; 0,50% e 0,45% para o máximo desempenho zootécnico; 0,42%; 0,33% e 0,31% para o equilíbrio orgânico e 0,78%; 0,77% e 0,71% para máxima mineralização óssea. Baixos níveis de fósforo nas rações resultaram em sinais de deficiência. Dietas contendo níveis adequados de fósforo para maximizar o crescimento dos peixes também permitem que eles mantenham os parâmetros metabólicos e fisiológicos em padrões de referência para peixes saudáveis. Recomenda-se a oferta de rações com 0,76%; 0,50% e 0,45% de fósforo disponível kg-1 ração, respectivamente, para peixes de 16 g – 100 g; 38 g – 250 g e 155 g – 350 g.
A method for non-destructive testing of the strength of a silica optical fiber
Authors:   FSBEI HE", Andreev V.A. ,   Povolzhskiy State University of Telecommunications and Informatics", Bourdine A.V. ,   FSBEI HE"Povolzhskiy State University of Telecommunications and Informatics",   S.I. Vavilov State Optical Institute, Burdin V.A. ,   FSBEI HE"Povolzhskiy State University of Telecommunications and Informatics", Dashkov M.V. ,   FSBEI HE"Povolzhskiy State University of Telecommunications and Informatics"
Published: June 2022

The paper proposes a method for non-destructive testing of the strength of an optical fiber based on estimates of the energy of nonlinear acoustic emission, based on the use of the tested optical fiber as an acoustic sensor. Models of the processes on which the method is based are presented. Results of experimental studies are presented. Data obtained from testing samples of the optical cables and optical fibers by the proposed method are compared with measurement results for the same samples obtained by the known 2-point method. The error in the estimates of the relative strength of the tested samples of optical fibers is found not to exceed 3.0 %. The results obtained allow us to suggest that the models used are correct and the proposed method shows promise for non-destructive testing of the strength of optical fibers, with the further development of the considered approach showing prospects for the application for non-destructive testing of the strength of optical fibers in a cable, including in-service cables.
Molecular Detection of Dipylidium caninum in Isolated Fleas of Dogs in Meshkinshahr County, Northwest of Iran
Authors: Azarm Amrollah , Dalimi Abdolhossein , Pirestani Majid , Mohammadiha Anita
Published: June 2022

Background: Fleas (Insecta: Siphonaptera) are considered as highly specialized bloodsucking on mammals such as humans, livestock, dog, cat, rabbit, squirrels, rats, and mice. The desire for blood feeding from warm-blooded animals has led to becoming an intermediate host for some tapeworms like Dipylidium. The aim of this study was to detect D. caninum larval infection in fleas of dogs living in Meshkinshahr County, northwest of Iran.
Methods: Fleas were collected from 42 dogs using brushing the hair in Meshkinshahr for one year (2014-2015). After the morphological study, fleas were preserved in 90% ethanol for molecular identification. After DNA extraction, the 28S ribosomal RNA gene (~670 bp) of D. caninum was amplified using specific primers. Finally, the PCR products were sequenced.
Results: Overs, 974 fleas were collected from the dogs. In the morphological study, three species Ctenocephalides canis, Ct. felis, and Pulex irritans were identified. PCR and sequence analysis results showed that 4 isolates Ct. Canis were infected with D. caninum. Also, no positive specimens were isolated from the other two species.
Conclusion: Ct. canis is reported as the most important species of fleas in transferring D. caninum in that region.
Isolation and Identification of Free Living Amoeba from Patients and Contact Lens Users in Iran
Authors: Jalilehvand Masoomeh , Hajialilo Elham , Ghiasi Yasaman , Rostamian Saba , Taherkhani Fatemeh , Kazemi Fatemeh , Hashemipour Sima , Badri Milad , Bijani Behzad , Javadi Amir , Saraei Mehrzad , Hajian Sepideh , Heydarian Peyman , Golezari Ali Sarbazi
Published: June 2022

Background: Free-living amoebae (FLA) such as Acanthamoeba spp., are considered as opportunistic and pathogenic protozoans.  Acanthamoeba granulomatous encephalitis (AGE) is a serious threat for immunodeficient patients and Acanthamoeba keratitis (AK) for contact lens users. We aimed to identify the presence of free living amoebae in nasal swabs of patients and contact lens users in Qazvin, Iran.
Methods: During 2019, 251 nasal and oral swabs (including the pharynx and mouth) were collected from patients with diabetes, AIDS and those under periodic dialysis in Qazvin, Iran. In addition, 27 soft contact lenses were collected from the participants. Following DNA extraction, PCR and sequencing were conducted to identify the genotypes of the amoeba. Phylogenetic analysis of the identified sequences was performed using MEGA 7 software.
Results: A strain of Acanthamoeba belonging to the T3 genotype was isolated from hemodialysis patients. Two specimens of Acanthamoeba with T3 genotype were isolated from keratitis patients.
Conclusion: The clinicians should pay attention to the possible complication of this organism because this amoeba is potentially pathogenic for immunocompromised patients. Since the amoeba is present in environmental resources, the use of contact lenses should be accompanied by considering proper hygiene.
Nanoincorporation of Plumbagin in Micelles Increase Its In Vivo Anti-Plasmodial Properties
Authors: Rashidzadeh Hamid , Zamani Payam , Amiri Mahdi , Hassanzadeh Seyed Mehdi , Ramazani Ali
Published: June 2022

Background: The application of plumbagin (PLN), with a wide use in pharmaceutical science, is limited due to its low water solubility and poor bioavailability. Micelles can encapsulate hydrophobic drugs due to their hydrophobic core. The aim of this study was to develop and characterize a polymeric micelle formulation of PLN and evaluate its in vivo anti-plasmodial property.
Methods: The study was conducted at Zanjan University of Medical Sciences, Zanjan, Iran in 2018. The triblock copolymeric micelles of PLN was prepared by e-caprolactone ring-opening polymerization, by PEG as the macroinitiator and using Sn(Oct)2 for its catalytic properties . The synthesized nanoparticles were characterized by 1H NMR, FTIR, GPC, AFM, and DLS. The encapsulation efficiency, drug loading capacity, and drug release were measured by UV-Vis at 520 nm. Also in vivo anti-plasmodial potential of fabricated drug loaded micelle was investigated using the 4-day suppressive test against Plasmodium berghei infection in mice.
Results: The nanoparticles average diameter was obtained less than 80 nm. The loading capacity and encapsulation efficiencies were 18.9±1.3% and 81±0.78%, respectively. In vitro, PLN release studies showed a sustained-release pattern until 7 days in PLN-loaded micelles (M-PLN) and drug release rate in acidic condition was higher than neutral condition. In vivo, anti-plasmodial results against P. berghei displayed an 8-fold increase in anti-plasmodial activity of M-PLN when compared to free PLN at the tested dosage level on the 7th day.
Conclusion: Based on these results, PCL–PEG–PCL micelles have a great potential to be the carrier for PLN for the malaria targeting.
Evaluation of the Protoscolicidal Effectiveness of Hypertonic Saline, Silver Nitrate, Ethanol, Using Sponge Pad Method and In-jecting into Fertile Hydatid Cysts
Authors: Fakharzadeh Jahromi Kereshmeh , Rafiei Abdollah , Rahdar Mahmoud , Bahreini Amin
Published: June 2022

Background: We aimed to evaluate currently protoscolices agents by using two methods including injection and impregnated sponges with protoscolices agents.
Methods: Hypertonic saline 20%, silver nitrate 0.5% and Ethanol 96% were injected into sheep hydatid cysts. Then, after different exposure times (5, 10, and 15 min), the protoscolices were aspirated from the cyst and viability of the protoscolices were evaluated microscopically using vital staining. In the second part, the live protoscolices were sprayed on the soaked sponge with the mentioned protoscolicidal agents. After different exposure times live protoscolices were counted microscopically. One-way ANOVA and Tukey tests were used for showing difference significant between studied groups.
Results: Cyst injection method showed that ethanol, Nacl and AgNo3 have 80%, 60% and 6% protoscolocidal efficacy, respectively (P<0.05). In sponge method the most and fastest protoscolocidal efficacy were observed in all used protoscolicidal agents.
Conclusion: Ethanol and NaCl and AgNo3 with sponge method is more effective than the injection of protoscolices agents in the cyst.
Evaluation of Echinococcosis Pre-Diagnosis Patients Admitted to the National Parasitology Reference Laboratory of Turkey from 2014-2019
Authors: Yücesan Banuçiçek , Babür Cahit , Kılıç Selçuk , Dikmen Asiye Uğraş
Published: June 2022

Background: Echinococcosis is a common parasite with zoonotic character created by a small cestode, Echinococcus spp., and is an important public health problem in Turkey as well as all over the world. We aimed to investigate antibodies in serum samples of suspected Echinococcosis patients sent to the National Parasitology Reference Laboratories of the General Directorate of Public Health.
Methods: Serum samples of 2390 patients sent to our laboratory between January 1, 2014 and May 01, 2019, evaluated by ELISA, Indirect Hemagglutination Test (IHA) and Western Blot (WB) methods are presented. Our laboratory is the national reference laboratory. All kinds of tests requested from suspected patients can be performed
Results: Overall, 1199 (50.2%) of 2390 serum samples were female and 1191 (49.8%) were male. It was observed that 178 (14.9%) of men and 210 (17.5%) of women were seropositive. There was no statistical difference between the sexes in terms of seropositivity. Of all samples, 1941 (81.2%) were negative, 388 (16.2%) were positive, and 61 (2.6%) were borderline. Results determined as borderline are considered suspicious and a recommendation is made to repeat the test after 15 days. A statistical difference was found in the distribution of seropositivity by years. While seropositivity was lowest in 2014, it was found to be highest in 2018 and 2019.
Conclusion: Despite all the precautions taken, it is seen that echinococcosis still continues to exist in Turkey as a zoonotic disease. Hence, CE has been involved in Turkey Zoonotic Diseases Action Plan (2019-2023) and decided to carry out studies for the protection and prevention of the disease.
Estimation of Injuries in a Population-based Study by Stratified Cluster Sampling and Network Scale-up Methods
Authors: Sehat Zahra , Fakharian Esmaeil , Sehat Mojtaba , Omidi Abdollah
Published: June 2022

Introduction: Today, one of the most important causes of morbidity and mortality among people all across the world is Injury. Injuries pose an important challenge for the health system and account for 28% of the deaths per day in Iran. Iran is in the 5th place for road traffic death rates globally.
Objective: This was a cross sectional study aimed to estimate annual incidence rates of injury in individuals above 15 in Kashan, Iran.
Methods: In this population-based cross-sectional study, people above 15 years in households residing in Kashan during 2018-2019 were studied The sample had a twofold design, Stratified Cluster Sampling method and network Scale-up method. Data analysis was performed using SPSS 22 (Chi-square and T-test and Logistic regression analysis) and Stata 14 software.
Results: This study describes the study setting, sampling, data collection and management, quality control and assurance, and the statistical analysis. In this study, the annual incidence rate from all kinds of trauma was estimated at 70.61(62.60-78.70) per 1000 person-years, and the death caused by injury was 4.63(34.32-56.12) per 1000 person-years. In addition, in network scale-up method incidence rate of all kinds of trauma was 57.1 and the death caused by trauma was 3.47 per 1000 person-years.
Conclusion: population-based studies were used to evaluate injuries and outcomes of trauma, so that managers realize where attention is needed regarding preventive programs in this city. Using indirect sampling techniques can be cost-effective and time-consuming, and can provide us with the information urgently needed.
Application of Mechanical Chest Compression Devices during Emergency Helicopter Flights
Authors: Esmaeilzadeh Mohammad Hossein , Moslehi Shandiz
Published: June 2022

The Article Abstract is not available.
Comparative analysis of allele frequencies for DNA polymorphisms associated with disease and economically important traits in the genomes of Russian and foreign cattle breeds
Authors: Igoshin A. V. , Romashov G. A. , Chernyaeva E. N. , Elatkin N. P. , Yudin N. S. , Larkin D. M.
Published: June 2022

The genetic makeup of a breed including its genetic differences from other breeds determines its appearance and characteristics, including economically important traits and resistance to pathologies. To date, many loci controlling significant phenotypes have been identified, which is successfully used in the world practice of marker-assisted selection to improve breed properties. The aim of this study was a comparative analysis of frequencies for known causative nucleotide substitutions, insertions and deletions associated with disease and economically important traits in Russian and foreign cattle breeds. As a result, we identified frequencies of these DNA polymorphisms in the populations of Russian cattle breeds, compared them with those of foreign populations of the same breed, as well as other foreign breeds. Our results indicate similarities in frequencies for most of such alleles within breeds (populations of Russian and foreign breeding), as well as the relationship between the causative allele prevalence and the presence of phenotypic traits under the effect. We also found an excess of some undesirable alleles in the Russian cattle populations, which should be paid attention to when designing breeding programs. We found that the alleles increasing fertility in the Hereford breed have a higher frequency in the Russian Hereford population compared to the foreign counterpart. Interestingly, unlike for the European breeds, for Asian Turano-Mongolian Wagyu and Yakut cattle, there was a less clear link between phenotypic traits and frequencies of known causative alleles. Our work points to specific genetic variants that could be used to improve and/or maintain the performance of certain cattle breeds bred in the Russian Federation.
An experimental study of the effects of SNPs in the TATA boxes of the GRIN1, ASCL3 and NOS1 genes on interactions with the TATA-binding protein
Authors: Sharypova E. B. , Drachkova I. A. , Chadaeva I. V. , Ponomarenko M. P. , Savinkova L. K.
Published: June 2022

The GRIN1, ASCL3, and NOS1 genes are associated with various phenotypes of neuropsychiatric disorders. For instance, these genes contribute to the development of schizophrenia, Alzheimer’s and Parkinson’s diseases, and epilepsy. These genes are also associated with various cancers. For example, ASCL3 is overexpressed in breast cancer, and NOS1, in ovarian cancer cell lines. Based on our findings and literature data, we had previously obtained results suggesting that the single-nucleotide polymorphisms (SNPs) that disrupt erythropoiesis are highly likely to be associated with cognitive and neuropsychiatric disorders in humans. In the present work, using SNP_TATA_Z-tester, we investigated the influence of unannotated SNPs in the TATA boxes of the promoters of the GRIN1, ASCL3, and NOS1 genes (which are involved in neuropsychiatric disorders and cancers) on the interaction of the TATA boxes with the TATA-binding protein (TBP). Double-stranded oligodeoxyribonucleotides identical to the TATA-containing promoter regions of the GRIN1, ASCL3, and NOS1 genes (reference and minor alleles) and recombinant human TBP were employed to study in vitro (by an electrophoretic mobility shift assay) kinetic characteristics of the formation of TBP–TATA complexes and their affinity. It was found, for example, that allele A of rs1402667001 in the GRIN1 promoter increases TBP–TATA affinity 1.4-fold, whereas allele C in the TATA box of the ASCL3 promoter decreases the affinity 1.4-fold. The lifetime of the complexes in both cases decreased by ~20 % due to changes in the rates of association and dissociation of the complexes (ka and kd, respectively). Our experimental results are consistent with the literature showing GRIN1 underexpression in schizophrenic disorders as well as an increased risk of cervical, bladder, and kidney cancers and lymphoma during ASCL3 underexpression. The effect of allele A of the –27G>A SNP (rs1195040887) in the NOS1 promoter is suggestive of an increased risk of ischemic damage to the brain in carriers. A comparison of experimental TBP–TATA affinity values (KD) of wild-type and minor alleles with predicted ones showed that the data correlate well (linear correlation coefficient r = 0.94, p < 0.01).
Forecast for the zone of viticulture in European Russia under climate change
Authors: Novikova L. Yu. , Ozerski P. V.
Published: June 2022

Climate warming has turned out to be a significant factor in viticulture and winemaking in all grape-growing areas of the world. Many countries consider the advance of viticulture to the north and to mountainous areas as a possible way to adapt to warming. The factors limiting the zone of viticulture in Russia have been identified by Soviet scientist F.F. Davitaya in 1948, and they are still relevant. They are the sum of active temperatures above 10 °C (ΣT10 > 2500 °C), mean of absolute minimum temperatures (Tmin > –35 °C), length of the frost-free period (Lff < 150 days), and hydrothermal coefficient (0.5 < HTC < 2.5). The values of these limiting factors in the present-day zone of commercial viticulture (ZCV) correspond to the ranges defined by F.F. Davitaya, with the exception of Tmin, which in the modern ZCV in European Russia is above –26 °C everywhere. The objective of this work was to assess the possibility of moving the boundaries of the ZCV to the north under the existing and predicted climate conditions in European Russia. The 1980–2019 daily data from 150 weather stations of the Federal Service for Hydrometeorology and Environmental Monitoring were used to calculate mean long-term values, trends and forecasts for 2050 for the ZCV limiting factors and locate the points lying in the range acceptable for viticulture. The QGIS program was applied to plot the points on the European Russia map and mark the terminal latitude. Versions with Tmin > –26 °C and Tmin > –35 °C were considered. On average for European Russia, in 1980–2019, there was an increase in ΣT10, Tmin, and Lff and a decrease in HTC. However, in the same period, Tmin showed a tendency toward decreasing at a number of points at latitudes lower than 55° N. The increase in heat supply during the growing season in European Russia implies a possibility of expanding the ZCV northward, beyond the present-day terminal latitude of 46.6° N, to 51.8° N under the existing conditions, and up to 60.7° N by 2050. In addition, even under the current conditions viticulture is possible in the area of Kaliningrad (54° N, 20° E). Using extra protective measures in winters not colder than –35 °C would make it possible to grow grapes at up to 53.3° N under the current conditions and at up to 60.7° N under the prognosticated ones. At the same time, a possible decrease in the minimum winter temperature at the south of European Russia will require additional protective measures in winter, while an increase in the aridity of the climate on the northwest coast of the Caspian Sea will reduce the area under non-irrigated vineyards.
Analysis of the low density lipoprotein receptor gene (LDLR) mutation spectrum in Russian familial hypercholesterolemia
Authors: Vasilyev V. B. , Zakharova F. M. , Bogoslovskaya T. Yu. , Mandelshtam M. Yu.
Published: June 2022

Familial hypercholesterolemia (FH) is a very common human hereditary disease in Russia and in the whole world with most of mutations localized in the gene coding for the low density lipoprotein receptor (LDLR). The object of this review is to systematize the knowledge about LDLR mutations in Russia. With this aim we analyzed all available literature on the subject and tabulated the data. More than 1/3 (80 out of 203, i. e. 39.4 %) of all mutations reported from Russia were not described in other populations. To date, most LDLR gene mutations have been characterized in large cities: Moscow (130 entries), Saint Petersburg (50 entries), Novosibirsk (34 mutations) and Petrozavodsk (19 mutations). Other regions are poorly studied. The majority of pathogenic mutations (142 out of 203 reported here or 70 %) were revealed in single pedigrees; 61 variants of mutations were described in two or more genealogies; only 5 mutations were found in 10 or more families. As everywhere, missense mutations prevail among all types of nucleotide substitutions in LDLR, but the highest national specificity is imparted by frameshift mutations: out of 27 variants reported, 19 (or 70 %) are specific for Russia. The most abundant in mutations are exons 4 and 9 of the gene due to their largest size and higher occurrence of mutations in them. Poland, the Czech Republic, Italy and the Netherlands share the highest number of mutations with the Russian population. Target sequencing significantly accelerates the characterization of mutation spectra in FH, but due to the absence of systematic investigations in the regions, one may suggest that most of LDLR mutations in the Russian population have not been described yet.
​Morphophenological Characters and Productivity of Pigeon Pea [Cajanus cajan (L.) Millsp.] as Influenced by Crop Geometry and Plant Growth Regulators
Authors: Pawar S.U. , Narkhede W.N. , Garud H.S. , Asewar B.V.
Published: June 2022

Background: Intensive cultivation with suitable crop geometry for optimum utilization of resources is one of the possible ways for increasing productivity of pigeonpea. Plant growth regulators have the capacity to stimulate and inhibit physiological processes, which directly or indirectly might affect crop yield and quality. This investigation was planned to study the influence of crop geometry and foliar application of plant growth regulators on production potential of pigeonpea. Methods: The field experiment was conducted at experimental farm of Agronomy Department, V.N.M.K.V., Parbhani, during kharif season of 2018 and 2019. The experiment was laid out in split plot design with four main plot treatments and five sub plot treatments. The main plot treatments comprised of four crop geometries while thesub plot treatments were five treatments on foliar application of plant growth regulatorsalongwith control. Result: Various crop geometries shown remarkable effect on growth and developement of pigeonpea. The crop geometry of 60-120 cm × 20 cm and 90 cm × 20 cm recorded maximum plant height of pigeonpea as compared to other wider crop geometries. While in case of all the other growth attributes viz. number of functional leaves plant-1, leaf area, number of branches plant-1 and dry matter accumulation plant-1 crop geometry of 120 cm × 20 cm and 75-150 cm × 20 cm were found superior as compared to other treatments and were at par with each other. The yield per hectare was increased at closer crop geometry 60-120 cm × 20 cm as the lower per plant yield was compensated by higher plant population. The crop geometry 60-120 cm × 20 cm produced significantly higher seed yield (1661, 1982 and 1821 kg ha-1 during 2018, 2019 and pooled mean respectively) over crop geometry of 120 cm × 20 cm and crop geometry 75-150 cm × 20 cm, but it was found at par with crop geometry 90 cm × 20 cm. Among the foliar application of plant growth regulators, growth characters viz., plant height, number of functional leaves, leaf area, number of branches and dry matter accumulation plant-1 as well as chlorophyll content were enhanced with the foliar application of Brassinosteroids @ 0.1 ppm and application of NAA @ 40 ppm during both the years of study. Foliar application of Brassinosteroids @ 0.1 ppm also recorded early flower initiation and significantly highest seed yield (1742, 2018 and 1880 kg ha-1 during 2018, 2019 and in pooled data, respectively), while it was at par with foliar application of NAA @ 40 ppm.
Countering master narratives with narratives of persistence: A liberation perspective in career counseling
Authors: Sensoy-Briddick Hande , Briddick William C.
Published: June 2022

As of 2019, the global youth population between the ages of 15 and 24 was 1.2 billion and growing (UNDESA, 2019). A sizable number of youth face discrimination and marginalization daily, often based on their social identities and related interlocking systems of power and oppression (Brewster & Molina, 2021). Minoritized youth, particularly, find themselves trapped in culturally manufactured master narratives that serve to reproduce the very systems of privilege that exist in their country (Liu, 2017). Considering these master narratives can be a significant step in our work with marginalized youth. Building on the contributions of leading scholars in career counselling, as well as other historically influential scholars in fields such as philosophy, education, and literature, we propose using narrative counselling and its related concepts to dismantle master narratives. In doing so, open spaces can emerge for alternative stories for the hopes, dreams, and futures of marginalized youth.

Keywords: Career; Master Narratives; Narrative Career Counselling
Belem Clark de Lara, “De la ecdótica a la hermenéutica. ‘Plato del día’ de Manuel Gutiérrez Nájera”, en (an)ecdótica, vol. 3, núm. 1 (2019), pp. 9-32.
Authors:   Instituto de Estudios Superiores de la Ciudad de México “Rosario Castellanos”, Ortega Itzel Patricia
Published: June 2022

Interesante reseña a un artículo de Belem Clark, publicado en la revista (an)ecdótica en su vol. 3, núm. 1 (2019).
Pediatric sudden sensorineural hearing loss: etiology, prognostic factors and treatment
Authors: AYSEL Abdulhalim , DALĞIÇ Abdullah , MÜDERRİS Togay , YILMAZ Fatih , ATSAL Görkem , BOYACIOĞLU Hayal , ÖZDEMİR ŞİMŞEK Özgür , ALTAŞ Enver
Published: June 2022

Aim: Sudden sensorineural hearing loss (SSNHL) may have a negative impact on the language and psychological development of children, especially if it is not diagnosed early and treated promptly. This study were aimed to determine and compare the etiological factors, treatment outcomes and prognostic factors in the pediatric patients who were followed up with the diagnosis of SSNHL.
Materials and Methods: The files of 28 children were analyzed retrospectively. In pure tone audiometry, the average of pure tone thresholds of 500 Hz, 1000 Hz, 2000 Hz and 4000 Hz were accepted as pure tone averages (PTAV). Patients' recovery status was determined according to Siegel criteria. Audiometric curve types were evaluated as ascending, descending, and flat.
Results: The ages of patients with SSNHL was mean ± SD 14.89 ± 3.24 (min-max: 7 and 18). The pre-treatment PTAV was mean ± SD 55.27 ± 12.39 dB HL (min-max: 38.5 and 85.25 dB HL) and the PTAV after treatment was mean ± SD 23.13 ± 18.22 dB HL (min-max: 5 and 72.5 dB HL). Audiometric curve types were detected as descending curve (n: 11, 39.2%), ascending curve (n: 5, 17.9%), flat curve (n: 12, 44.9%). Eighteen (64.3%) patients had complete recovery, 8 (28.6%) patients had partial recovery, and 2 (7.1%) patients had no recovery after the treatment.
Conclusion: The response to treatment was found to be high. Descending audiometric curve type was found as a positive prognostic factor. Although the presence of tinnitus was a better prognostic factor than the presence of vertigo.
Continuum histórico e normatizações em acervos de arte e datasets
Authors: Moreschi Bruno , Jurno Amanda , Beiguelman Giselle
Published: June 2022

Este artigo apresenta um conjunto de experimentos no campo da História da Arte com tecnologias de Inteligência Artificial (visão computacional) realizados no âmbito do demonumenta, um projeto de pesquisa e extensão universitária que busca tensionar crítica e criativamente políticas públicas de memória. A partir do entendimento de que datasets (conjuntos de dados organizados) e acervos artísticos são práticas análogas, questionamos como trabalhar nesta intersecção para subverter os pressupostos normativos que caracterizam a organização de coleções de arte, bancos de dados e os discursos que suas ferramentas enunciam. Acreditamos que parte desta resposta está na ativação crítica de acervos públicos para reformular o modo como hoje treinamos as máquinas. Para tanto, elaboramos um dataset, com base nas obras do Museu Paulista da Universidade de São Paulo (USP) disponíveis no seu GLAM (Galleries, Libraries, Archives & Museums) nos projetos Wiki. A sistematização desse dataset foi a base para a realização de cinco experimentos analíticos com algoritmos de Inteligência Artificial. São eles: Naturezas Numéricas, Paisagens Possíveis, Arqueologia das Cores, Álbum Afirmativo e Ignorância Animada. Tais experimentos evidenciam o continuum colonialista que elabora a narrativa histórica a partir de parâmetros e padrões visuais normatizantes.
A mucoadhesive gingival patch with Epigallocatechin-3-gallate green tea (Camellia sinensis) as an alternative adjunct therapy for periodontal disease: A narrative review
Authors: Ramadhani Yeka , Rahmasari Riski Rahayu Putri , Prajnasari Kinanti Nasywa , Alhakim Moh. Malik , Aljunaid Mohammed , Al-Sharani Hesham Mohammed , Tantiana T. , Juliastuti Wisnu Setyari , Ridwan Rini Devijanti , Diyatri Indeswati
Published: June 2022

Background: Periodontitis is a progressive destructive periodontal disease. The prevalence of periodontal disease in Indonesia reaches 74.1% and mostly occurs in the productive age group. Most of the periodontopathogenic bacteria are gram-negative bacteria and have endotoxin in the form of lipopolysaccharide (LPS), which can penetrate the periodontal tissue and induce an inflammatory response. In inflammatory conditions, osteoclastic activity is higher than osteoblastic activity, which causes bone destruction. This results in an imbalance between osteoclast-induced bone resorption and osteoblast-induced bone formation. The current preferred treatment for periodontitis is scaling root planning (SRP), but this therapy cannot repair the damaged periodontal tissue caused by periodontitis. Purpose: To describe the possibility of using a mucoadhesive gingival patch with Epigallocatechin-3-gallate (EGCG) green tea (Camellia sinensis) as alternative adjunct therapy for periodontal disease. Review: EGCG is the main component of green tea catechins, which have antitumor, antioxidant, anti-inflammatory, anti-fibrotic, and pro-osteogenic effects. However, the weaknesses so far regarding the use of EGCG as an alternative treatment is its low oral bioavailability and the concentration of EGCG absorbed by the body decreasing when accompanied by food. EGCG can be used with a mucoadhesive gingival patch to optimise bioavailability and absorption and increase local concentration and sustained release of EGCG. EGCG encourages bone development and braces mesenchymal stem cells (MSCs) differentiation for osteoblast by enhancing the expression of bone morphogenic protein 2 (BMP2). EGCG also has been proven to increase the expression of RUNX2 and ALP activity that induces osteoblast differentiation and bone mineralisation. Conclusion: A mucoadhesive gingival patch containing EGCG Green Tea (C. sinensis) may potentially induce osteoblastic activity as an adjunct therapy to repair the periodontal tissue damage due to periodontal disease.
Anemia prevention behavior in female adolescents and related factors based on Theory of Planned Behavior: A cross-sectional study
Authors: Puspitasari Halfie Zaqiyah Gusti , Armini Ni Ketut Alit , Pradanie Retnayu , Triharini Mira
Published: June 2022

Introduction: Female adolescent is a group prone to iron deficiency anemia due to various factors such as having monthly menstruation and poor diet. Therefore, anemia prevention behavior needs to be done from an early age to avoid prolonged health problems. The purpose of this study was to analyze the factors that correlated with anemia prevention behavior in female adolescents based on the Theory of Planned Behavior.

Methods: This study used a descriptive correlational design with a cross-sectional approach. The population of this study is female adolescents in Madiun City. Purposive sampling was used to obtain 105 respondents. The instrument used was a questionnaire to measure the variables attitude, subjective norm, perceived behavioral control, intention, and anemia prevention behavior. Data analysis was performed using the Spearman Rho Test with a level of significance ≤ 0.05.

Results: There is a relationship between attitudes (p = 0.003; r = 0.292), subjective norms (p = 0.006; r = 0.266), and perceived behavioral control (p= 0.002; r = 0.299) with the intention to prevent anemia and also perceived behavioral control (p = 0.003; r = 0.292) and intention (p = 0.000; r =0.392) with anemia prevention behavior.

Conclusions:
Better attitude, subjective norm, perceived behavioral control, and intention possessed by a female adolescent will make better anemia prevention behavior too. Therefore, support from various parties is needed to intensify the promotion of anemia prevention, education on early detection of anemia, especially for female adolescents, and further research to determine effective health promotion methods.