bluuebunny/crossref_metadata_2025 huggingface dataset:
A Critical Review of Recent Development in Li-Ion Battery Cooling Using Advance Phase Change Materials
Authors: Thakur Amrit Kumar , Sathyamurthy Ravishankar , Saidur R , Pandey A. K. , Sharshir Swellam W. , S Christopher
Published: December 2021

Electric vehicles (EVs) can significantly reduce the greenhouse gas emissions, compared to traditional fuel vehicles and also effectively reduced the severe increasing pollution from transportation sector. EVs technology are the alternative of petrol/diesel vehicles, however performance of the power batteries in the major concerns. Li-ion battery (LiBs) are very sensitive to the temperature, which drastically affect the lifespan, thermal performance and safety. Battery thermal management (BTMSs) in thus an essential and it can considerably decrease the adversative effect of high battery cells temperature. In this regard, this work presents a detailed review of BTMSs using phase change materials (PCMs), including metal-foam based PCM, nano-particles dispersed PCM and fin insertion in PCM. It is found that the PCM through utilization of nano-particles possesses excellent thermal properties for effective heat dissipation of the battery pack and highly advantageous. In future, advanced BTMS for fast-charging EVs working at high temperature, hydride BTMS through utilization of heat pipes with forced air cooling and nano-particles will be advantageous. The tactic presented for battery cooling herein can be utilized by the EV industry in fast-charging based vehicle conditions.
Photoassisted Electrodeposition of Cuprous Oxide Thin Films
Authors: Mairhofer Katharina , Kipper-Pires Bettina , Leitner Gerhard , Fafilek Guenter
Published: December 2021

Well-defined cuprous oxide (Cu2O) thin films can be electrodeposited from an electrolyte containing copper (II) sulfate, lactic acid and sodium hydroxide. As Cu2O is a p-type semiconductor, it is possible to accelerate the process through illumination with light of sufficient energy (>2.1eV). Cyclic voltammetry and transient potentiostatic measurements were performed in a three-electrode setup with copper metalized wafers as a working electrode. Illumination was performed through the electrolyte, therefore absorption of light by the electrolyte had to be taken into consideration. Potentiostatic measurements with a blue LED as a light source have shown an tenfold increase in layer thickness in comparison to depositions without additional illumination. The deposited films were investigated with SEM analysis.
Influence of Different Solutions on Corrosion Materials Based on Fe-Mg
Authors: Sedlarikova Marie , Zatloukal Miroslav , Hrabovský Jan , Čudek Pavel
Published: December 2021

This work deals with a current topic, which are biodegradable sintered Fe-based materials and their corrosion. These materials may be suitable for applications where gradual decomposition is required. An important parameter is not only the mechanical properties so that the material can withstand the load, but above all the corrosion properties and the degradation process. In this work, sintered materials based on Fe-Mg are tested. The introductory part is an introduction to the corrosion processes of the basic components of the tested systems, i.e. Fe. The practical part is focused on the preparation of samples based on Fe with the doping element Mg.
Determining the Electrical Capacity of Lithium BEV and PHEV Battery in Situ
Authors: Maule Petr , Vanek Jiri , Jandová Kristýna
Published: December 2021

The work deals with the quality of batteries in electric vehicles manufactured today’s and the determination of warranty conditions and guarantees for built-in lithium batteries. However, the design, testing, prototyping and creation of new vehicles is not without errors, as the experience of some manufacturers, including the more inexperienced Mercedes, shows now. On a tested sample of the Mercedes E350e PHEV, a capacity loss of more than 30% from the original nominal value was measured after 18 months of vehicle operation, well above the manufacturer's expectations and declarations.
Estimation of Depth of Discharge of Li-ion Battery Using Neural Network
Authors: Cipin Radoslav , Toman Marek , Prochazka Petr , Pazdera Ivo
Published: December 2021

This paper deals with the estimation of depth of discharge for Li-ion batteries. Estimation is based on the knowledge of discharging curves measured for discrete values of loading currents. The estimator of the depth of discharge is a form of feedforward neural network which is trained with the measured data of discharge curves. Accuracy of estimation of the depth of discharge is shown for arbitrary generated and measured loading characteristics, where the depth of discharge is estimated by the designed neural network and measured by using the Coulomb counting method.
Numerical Modeling of Cyclic Voltametry
Authors: Vyroubal Petr , Mačák Martin
Published: December 2021

This paper deals with a new approach to numerical modeling of cyclic voltammetry using the CFD solver FLUENT. The standard use of this solver is in the field of flow and heat transfer calculations, however, it is possible to model electrochemical reactions and it also includes basic models for calculations related to batteries, such as charging and discharging processes, temperature fields, etc. Thanks to the possibility of scripting, however, it is possible to extend these tasks to a much more complex level.
Numerical Investigation of Cathode Structure Influence on Electrochemical Behavior of Lithium-Sulfur Battery
Authors: Mačák Martin , Jasso Kamil , Vyroubal Petr , Kazda Tomáš , Cudek Pavel
Published: December 2021

Nowadays, Lithium-Sulfur batteries are often considered as the next generation technology for energy storage systems. This article investigates the influence of the size of sulfur clusters present in the cathode on the battery overall electrochemical behavior. The properties of the cathode are studied by cyclic voltammetry simulations using a custom numerical model implemented into Ansys Fluent. The simulation is supplemented by experimental cyclic voltammetry measurements and images from a scanning electron microscope.
Epoxy Casting Systems with Harmless Hardeners for Outdoor Applications
Authors: Horak Ludek , Kazelle Jiri , Safl Pavel
Published: December 2021

Presented thesis is focused on studying of electro-insulating casting systems based on epoxy resin. The aim of the article is to acquaint the reader with the development of this systems – epoxy resin with hardeners that comply with REACH authorization. The temperature and frequency dependence of complex permittivity, complex electric modulus, loss factor and inner and surface resistivity of the given samples are investigated.
Novel Spherical Fuzzy MARCOS Method for Assessment of Drone‐Based City Logistics Concepts
Authors: Kovač Milovan , Tadić Snežana , Krstić Mladen , Bouraima Mouhamed Bayane
Published: December 2021

Technological innovations from the last few years, in the combination with city logistics (CL) initiatives, make the definition of novel, complex, sustainable CL solutions possible. Unmanned aerial vehicles (drones) as a technology attracted lots of attention in the literature. Various researches focused on different drone‐based delivery approaches, but there are only a few articles dealing with drones as the elements of complex CL concepts. The goal of this paper is to evaluate different drone‐based CL concepts. Based on the existing ideas of drone application in delivery, the main group of CL concepts and their variants are defined, which represents the main contribution of the article. The evaluation and ranking of concepts are performed from the aspect of all CL stakeholders and the defined set of criteria by applying measurement of alternatives and ranking according to compromise solution (MARCOS) multicriteria decision‐making (MCDM) method in spherical fuzzy environment, which represents another contribution of the article. The results indicate that the potentially best CL concept, with the final score of 0.408, is the one that refers to the transformation of the logistics system into a two‐echelon system with the implementation of micro‐consolidation centers (MCCs), in which the delivery of goods to MCCs is realized with rail transportation mode and the last delivery phase with drones. It is followed by the concepts that imply MCCs, and rail transportation in the function of mobile depots for drone launching and MCCs and ground delivery vehicles (GDVs), with the final scores of 0.395 and 0.390, respectively.
Predicting the Direction Movement of Financial Time Series Using Artificial Neural Network and Support Vector Machine
Authors: Ali Muhammad , Khan Dost Muhammad , Aamir Muhammad , Ali Amjad , Ahmad Zubair
Published: December 2021

Prediction of financial time series such as stock and stock indexes has remained the main focus of researchers because of its composite nature and instability in almost all of the developing and advanced countries. The main objective of this research work is to predict the direction movement of the daily stock prices index using the artificial neural network (ANN) and support vector machine (SVM). The datasets utilized in this study are the KSE‐100 index of the Pakistan stock exchange, Korea composite stock price index (KOSPI), Nikkei 225 index of the Tokyo stock exchange, and Shenzhen stock exchange (SZSE) composite index for the last ten years that is from 2011 to 2020. To build the architect of a single layer ANN and SVM model with linear, radial basis function (RBF), and polynomial kernels, different technical indicators derived from the daily stock trading, such as closing, opening, daily high, and daily low prices and used as input layers. Since both the ANN and SVM models were used as classifiers; therefore, accuracy and F‐score were used as performance metrics calculated from the confusion matrix. It can be concluded from the results that ANN performs better than SVM model in terms of accuracy and F‐score to predict the direction movement of the KSE‐100 index, KOSPI index, Nikkei 225 index, and SZSE composite index daily closing price movement.
Comparison of the Postoperative Effects of Local Antibiotic versus Systemic Antibiotic with the Use of Platelet‐Rich Fibrin on Impacted Mandibular Third Molar Surgery: A Randomized Split‐Mouth Study
Authors: Donmezer Ceren Melahat , Bilginaylar Kani
Published: December 2021

The surgery of the impacted mandibular third molar is the most frequent procedure in dentistry. The prescription of systemic antibiotics after the third molar extraction is widespread among dentists, but this is still argumentative. This study is aimed at evaluating the postoperative effects of local antibiotic mixed with platelet‐rich fibrin (PRF) and a postoperative systemic antibiotic prescribed for mandibular third molar surgery. The study included 75 patients divided into a control and 4 test groups (n = 15). In the control group, only PRF was placed into the extracted socket, and no antibiotic was prescribed. In the first and third groups, PRF was applied to the socket; penicillin and clindamycin were prescribed as oral medications, respectively. In the second and fourth groups, only PRF combined with penicillin and clindamycin was applied into the socket, respectively. The outcome variables were pain, swelling, analgesic intake, and trismus. These variables were also assessed based on the first, second, third, and seventh days following the operation. Unpaired Student’s t‐test and Mann–Whitney U test were used for analysis. There were significant differences in the total VAS pain scores between the control and group 3 (p < 0.05), groups 1 and 2 (p < 0.01), and group 4 (p < 0.001) in ascending order. For analgesic intake, there was no significant difference for group 1 (p > 0.05). However, there were statistical differences between the control group and groups 2 and 3 (p < 0.01) and group 4 (p < 0.001). Trismus and swelling did not differ among the groups (p > 0.05). This study showed that the effects of local and systemic antibiotics with the use of PRF reduced postoperative outcomes. Moreover, local antibiotics with PRF may be a viable method to avoid the possible side effects of systemic antibiotics.
Analysis of the Effect of Cluster Nursing in Postoperative Hypertensive Cerebral Hemorrhage
Authors: Zheng Pingxia , Wang Jia , Ma Yan , Xu Jingjing , Zhu Qianping
Published: December 2021

Hypertensive intracerebral hemorrhage is a common condition in clinic. Due to the improvement of minimally invasive technology, its therapeutic effect is good, but there are still postoperative complications. The corresponding routine nursing intervention is not effective in the rehabilitation of postoperative patients with hypertensive intracerebral hemorrhage. In this paper, cluster nursing was applied to the treatment of postoperative patients with hypertensive intracerebral hemorrhage. For this purpose, a retrospective study or experiment was conducted on 150 patients with hypertensive intracerebral hemorrhage in the hospital specifically from January 2019 to December 2020. According to the nursing strategy, patients were divided into experimental (n = 75) and control groups (n = 75), respectively. The control group adopted routine nursing mode, whereas the experimental group adopted cluster nursing mode. The treatment compliance of patients in the experimental group was 86.67%, while that in the control group was 73.33% (

P

 < 0.05). The total incidence of postoperative complications in the experimental group was 3.2%, which was lower than 25% in the control group (

P

 < 0.05). The motor function score of the experimental group was better than that of the control group (

P

 < 0.05). The application of cluster nursing in postoperative patients with hypertensive intracerebral hemorrhage is feasible, and its nursing effect is significant, which can not only reduce the incidence of postoperative complications but also improve patients’ compliance and quality of life. It has good application value.
Numerical Analysis of
Cu
+

Al

2

O

3

/

H

2

O

Hybrid Nanofluid of Streamwise and Cross Flow with Thermal Radiation Effect: Duality and Stability
Authors: Dero Sumera , Lund Liaquat Ali , Shah Zahir , Bonyah Ebenezer , Deebani Wejdan
Published: December 2021

The motion of water conveying copper and aluminum nanoparticles on a heated moving sheet when thermal radiation and stretching/shrinking surface is significant and is investigated in this study to announce the increasing effects of volume fractions, thermal radiation, and moving parameters on this transport phenomenon. Furthermore, the flow of a

Cu
−

Al

2

O

3

/water hybrid nanofluid across a heated moving sheet has been studied in both cross and streamwise directions. Thermal radiation effect is also considered, as this effect along with cross flow has not yet been investigated for the hybrid nanofluid in the published literature. Two distinct types of nanoparticles, namely,

Al

2

O

3

(alumina) and

Cu

(copper), have been used to prepare hybrid nanofluid where water is considered as a base fluid. The system of nonlinear partial differential equations (PDEs) has been transferred to ordinary differential equations (ODEs) by compatible transformations before solving them by employing the III-stage Lobatto-IIIa method in bvp4c solver in MATLAB 2017 software. Temporal stability analysis has been carried out in order to verify stable branch between two branches by obtaining the smallest eigenvalue values. The branches obtained are addressed in depth against every applied parameter using figures and tables. The results show that there are three ranges of branches, no solution exists when

λ
>

λ

c

, dual branches exist when

0.23
≤
λ
≤

λ

c

, and a single solution exists when

λ
>
0.23

. Moreover, thermal layer thickness declines initially and then enhances in the upper and lower solutions for the higher values of the thermal radiation parameter.
Prevalence and Risk Factors of Bovine and Ovine Lungworm Infection at Durame District, Southern Ethiopia
Authors: Fesseha Haben , Mathewos Mesfin
Published: December 2021

Background. Lungworms are parasitic nematodes of the order Strongylidae that infect the lungs of cattle and sheep and cause bronchitis or pneumonia. Methods. An abattoir-based cross-sectional study was conducted from November 2018 to April 2019 to determine the comparative prevalence and the possible risk factors of lungworm infection in sheep and cattle of Durame district of Kembata Tembaro zone. For this purpose, a total of 410 animals (209 sheep and 201 cattle) were randomly selected and examined for the presence of different lungworm species using the modified Baermann technique and postmortem examination. The sensitivity and specificity of fecal sample test considering necropsy as reference/gold standard was conducted. Results. Accordingly, the overall prevalence of lungworm infection in sheep and cattle was 24.39%. Dictyocaulus filaria and D. viviparous were the only species of lungworm identified in sheep and cattle with a respective prevalence of 44.02% and 3.98%. Putative risk factors such as species and poor body condition have a significant association (

p
<
0.05

) with the occurrence of lungworms in sheep and cattle. The lungworm infection was higher in the young age group (25.30%) and poor body conditioned (32.14%) animals. Season-wise prevalence revealed that a higher lungworm infection was recorded during autumn (32.14%) as compared to winter (22.81%) and spring (16.2%). Most of the sheep and cattle in the current study were heavily (45.0%) and moderately (39.0%) infected with lungworms whereas the rest 16.0% were infected with a low degree of lungworm infection. The specificity, sensitivity, PPV, and NPV of the modified Baermann technique against the gold standard test were 89.4%, 42%, 56.0%, and 82.7%, respectively. Conclusion. The study revealed that lungworm infection is prevalent in sheep and cattle of the study area and that was commonly occurs during autumn and affects poorly conditioned sheep and cattle. Thus, routine and strategic deworming for the control and prevention of lungworms in domestic animals should be recommended to overwhelm the prevalence of lungworm infection.
Application of Magnetic Resonance Imaging of Patients with Concussion in Clinical Emergency
Authors: Fang Peng , Lin Dezhao , Xu Ka , Ying Shangyan
Published: December 2021

Concussion syndrome is a common disease in neurosurgery, and its incidence ranks first among all traumatic brain injuries. Cognitive dysfunction is one of the most common functional impairments in concussion syndrome. Neuroimaging and content assessments on concussion patients and healthy control subjects are used in this study, which uses MRI technology to evaluate brain pictures of concussion patients. Moreover, this paper separately evaluates the scores of the concussion syndrome group and the healthy control group in multiple functional aspects and performs independent sample

t

-test after statistics of the two scores. In addition, this paper uses resting-state fMRI to study the changes in the functional connectivity of the medial prefrontal lobe in patients with PCS, which has certain significance in revealing cognitive dysfunction after concussion and has a certain effect on improving the clinical emergency diagnosis and treatment of concussion.
Study of Keyword Extraction Techniques for Electric Double‐Layer Capacitor Domain Using Text Similarity Indexes: An Experimental Analysis
Authors: Miah M. Saef Ullah , Sulaiman Junaida , Sarwar Talha Bin , Zamli Kamal Z. , Jose Rajan
Published: December 2021

Keywords perform a significant role in selecting various topic‐related documents quite easily. Topics or keywords assigned by humans or experts provide accurate information. However, this practice is quite expensive in terms of resources and time management. Hence, it is more satisfying to utilize automated keyword extraction techniques. Nevertheless, before beginning the automated process, it is necessary to check and confirm how similar expert‐provided and algorithm‐generated keywords are. This paper presents an experimental analysis of similarity scores of keywords generated by different supervised and unsupervised automated keyword extraction algorithms with expert‐provided keywords from the electric double layer capacitor (EDLC) domain. The paper also analyses which texts provide better keywords such as positive sentences or all sentences of the document. From the unsupervised algorithms, YAKE, TopicRank, MultipartiteRank, and KPMiner are employed for keyword extraction. From the supervised algorithms, KEA and WINGNUS are employed for keyword extraction. To assess the similarity of the extracted keywords with expert‐provided keywords, Jaccard, Cosine, and Cosine with word vector similarity indexes are employed in this study. The experiment shows that the MultipartiteRank keyword extraction technique measured with cosine with word vector similarity index produces the best result with 92% similarity with expert‐provided keywords. This study can help the NLP researchers working with the EDLC domain or recommender systems to select more suitable keyword extraction and similarity index calculation techniques.
Application of Mesoscale Simulation to Explore the pH Response of Eudragit S100 Used as the Novel Colon-Targeted Powder of Pulsatilla Saponin D
Authors: Gong Mingcheng , Chen Zhenhua , Zhou Liangliang , Gao Feng , Cheng Jianxin , Zou Wanqing
Published: December 2021

As a pH-sensitive nanomaterial, Eudragit S100 has good colon targeting. However, little research has been carried out on its mesoscopic scale. In this paper, the self-assembly behavior of Pulsatilla saponins D (PSD) and Eudragit S100, as well as the loading and release mechanism of PSD, was investigated via computer simulations. The effects of the self-assembly characteristics of PSD and Eudragit S100 in the dry powder state on the drug-carrier ratio were explored by the coarse-grained molecular dynamics (CGMD) method. According to the pH-responsive feature of Eudragit S100, the drug protection under gastric pH conditions and release in colonic pH conditions were simulated through the dissipative particle dynamics (DPD) method, which has provided insights into the microscopic morphological changes in the pH-sensitive drug delivery systems.
Analysis of Internet Marketing Forecast Model Based on Parallel K-Means Algorithm
Authors: Chen Xiaolei , Ge Sikun
Published: December 2021

Based on the parallel K-means algorithm, this article conducts in-depth research on the related issues of marketing node detection under the Internet, including designing a new Internet marketing node detector and a location summary network based on FCN (Full Convolutional Network) to input the preprocessing of the node and verify its performance under the data sets. At the same time, to solve the problem of insufficient data sets of Internet marketing nodes, the Internet data sets are artificially generated and used for detector training. First, the multiclass K-means algorithm is changed to two categories suitable for Internet marketing node detection: marketing nodes and background categories. Secondly, the weights in the K-means algorithm are mostly only applicable to target detection tasks. Therefore, when processing Internet marketing node detection tasks, the K-means algorithm is used to regress the training set and calculate 5 weights. During the simulation experiment, the weight calculation formula is used to calculate the weight of the feature term. The basic idea is that if a feature word appears more often in this document but less frequently in other nodes, the word will be assigned higher. At the same time, this article focuses on k. Some shortcomings of the mean clustering algorithm have been specifically improved. By standardizing the data participating in the clustering, the data participating in the clustering is transformed from an irregular distribution to a cluster-like distribution, thereby facilitating the clustering process. The density is introduced to determine the initial center of the cluster, and the purity metric is introduced to determine the appropriate density radius of the cluster center, to achieve the most effective reduction of the support vector machine training samples.
Acute Whole‐Body Vibration Exercise Promotes Favorable Handgrip Neuromuscular Modifications in Rheumatoid Arthritis: A Cross‐Over Randomized Clinical
Authors: Coelho-Oliveira Ana Carolina , Lacerda Ana Cristina Rodrigues , de Souza Ana Lúcia Cristino , Santos Luciana Martins de Mello , da Fonseca Sueli Ferreira , dos Santos Jousielle Márcia , Ribeiro Vanessa Gonçalves César , Leite Hércules Ribeiro , Figueiredo Pedro Henrique Scheidt , Fernandes José Sebastião Cunha , Martins Fábio , Filho Renato Guilherme Trede , Bernardo-Filho Mario , da Cunha de Sá-Caputo Danúbia , Sartorio Alessandro , Cochrane Darryl , Lima Vanessa Pereira , Costa Henrique Silveira , Mendonça Vanessa Amaral , Taiar Redha
Published: December 2021

Objective. Rheumatoid arthritis (RA) causes progressive changes in the musculoskeletal system compromising neuromuscular control especially in the hands. Whole‐body vibration (WBV) could be an alternative for the rehabilitation in this population. This study investigated the immediate effect of WBV while in the modified push‐up position on neural ratio (NR) in a single session during handgrip strength (HS) in women with stable RA. Methods. Twenty‐one women with RA (diagnosis of disease: ±8 years, erythrocyte sedimentation rate: ±24.8, age: 54± 11 years, BMI: 28 ± 4 kg·m-2) received three experimental interventions for five minutes in a randomized and balanced cross‐over order: (1) control—seated with hands at rest, (2) sham—push‐up position with hands on the vibration platform that remained disconnected, and (3) vibration—push‐up position with hands on the vibration platform turned on (45 Hz, 2 mm, 159.73 m·s-2). At the baseline and immediately after the three experimental interventions, the HS, the electromyographic records (EMGrms), and range of motion (ROM) of the dominant hand were measured. The NR, i.e., the ratio between EMGrms of the flexor digitorum superficialis (FDS) muscle and HS, was also determined. The lower NR represented the greater neuromuscular efficiency (NE). Results. The NR was similar at baseline in the three experimental interventions. Despite the nonsignificance of within‐interventions (p = 0.0611) and interaction effect (p = 0.1907), WBV exercise reduced the NR compared with the sham and control (p = 0.0003, F = 8.86, η2 = 0.85, power = 1.00). Conclusion. Acute WBV exercise under the hands promotes neuromuscular modifications during the handgrip of women with stable RA. Thus, acute WBV exercise may be used as a preparatory exercise for the rehabilitation of the hands in this population. This trial is registered with trial registration 2.544.850 (ReBEC‐RBR‐2n932c).
Analysis on Evolutionary Stability Strategies of Carbon Emission of Logistics Enterprises Based on Carbon Tax
Authors: Wu Xiaoping , Liu Peng , Wei Qi
Published: December 2021

In view of the problem of high carbon emissions of logistics enterprises, the government’s carbon tax policy, consumers’ willingness to purchase low-carbon services, and the carbon emission reduction behavior of logistics enterprises, the evolutionary game model between the government, consumers, and logistics enterprises is established by using the theory and method of evolutionary game, and the evolutionary stabilization strategies of the three parties under different parameters are analyzed. The research results show the following. (1) When setting the carbon tax rate, the government can ignore the impact on consumers and give more consideration to the influencing factors of logistics enterprises, which is conducive to the formulation of carbon emission reduction policies for logistics enterprises. (2) When the government sets a lower carbon tax rate, it can not only promote the carbon emission reduction of logistics enterprises but also be conducive to government supervision. (3) The evolution direction of the government’s final decision will not change due to the size of Y and Z. The government’s final decision is to adopt a regulatory strategy. The study provides theoretical guidance for the government to formulate carbon tax policies, guides consumers to purchase low-carbon services, and promotes carbon emission reduction in logistics enterprises.
Mortality Risk within 14 Days after Coronavirus Disease 2019 Diagnosis in Dementia Patients: A Nationwide Analysis
Authors: Kim Yi-Jun , Jee Yongho , Park Sholhui , Ha Eun-Hee , Jo Inho , Lee Hyang Woon , Song Myung Seon
Published: December 2021

Introduction: The study evaluated the increased mortality risk within 14 days of coronavirus disease 2019 (COVID-19) diagnosis in dementia patients. Methods: This retrospective study was conducted from February to April 2020 using the COVID-19 patients’ database from the Korea Disease Control and Prevention Agency. The risk factors for early death within 14 days were determined using generalized logistic regression performed in a stepwise manner. Dementia patients diagnosed with COVID-19 were used for the study. The propensity score-matched cohort was included as controls. The differences in mortality within 14 days after COVID-19 diagnosis between the dementia patients and controls were evaluated. Results: We enrolled 5,349 COVID-19 patients from the database; 224 had dementia as comorbidity. The mortality rate within 14 days after COVID-19 diagnosis in dementia patients and the controls was 23.7% versus 1.7%, respectively, before propensity score matching (PSM) (p < 0.001), and 23.7% versus 9.2% after PSM (p < 0.001). The hazard ratio (HR) for mortality within 14 days in COVID-19 patients with dementia was significant even after PSM (HR 5.104, 95% confidence interval 2.889–5.673, p < 0.001). The survival curve of dementia patients was steeply inclined within 14 days after COVID-19 diagnosis, resulting in 70.7% of all deaths in dementia patients. Conclusions: COVID-19 patients with dementia had a higher risk of early death within 14 days. Thus, prompt intervention is necessary for dementia patients after COVID-19 diagnosis.
A low power comparator utilizing MTSCStack, DTTS, and bulk-driven techniques
Authors: Mustaffa Mohd Tafir
Published: December 2021

Comparator is one of the main blocks that play a vital task in the performance of analog to digital converters (ADC) in all modern technology devices. High-speed devices with low voltage and low power are considered essential for industrial applications. The design of a low-power comparator with high speed is required to accomplish the requirements mostly in electronic devices that are necessary for high-speed ADCs. However, a high-speed device that leads the scaling down of CMOS process technology will consume more power. Thus, power reduction techniques such as multi-threshold super cut-off stack (MTSCStack), dual-threshold transistor stacking (DTTS), a bulk-driven, and a bulk-driven differential pair were studied in this work. This study aims to find and build the combination of these techniques to produce a comparator that can operate in low power without compromising existing performance using the 0.13-µm CMOS process. A comparator with a combination of MTSCStack, DTTS, and NMOS bulk-driven differential pair shows the most promising result of 6.29 µW for static power, 17.15 µW for dynamic power, and 23.44 µW for total power.
Curcumin as an Anti-Proliferative Agent in Breast Cancer through RASSF1A, Bax, and Caspase-3 Protein
Authors: Rahma Nunung Ainur , Harliansyah  , Suyatna Fransiscus D. , Kanoko Mpu , Rustamadji Primariadewi , Prihartono Joedo , Bustami Arleni , Haryono Samuel Johny , Hernowo Bethy Suryawati
Published: December 2021

Introduction: Curcumin is a polyphenol that has pharmacological activity that can inhibit tumor cell growth and induce apoptosis through various mechanisms. However, the specific mechanism of curcumin cytotoxicity remains controversial because of many anti- and pro-apoptotic signaling pathways in various cell types. This study aims to examine the relationship among curcumin on RASSF1A, Bax protein levels, and caspase-3 activity in supporting the apoptotic mechanism in CSA03 breast cancer cells. Method: Curcumin administration to cancer cells is based on differences in dosage with 24-hour incubation. Cytotoxicity after curcumin administration was determined using MTS. RASSF1A and Bax protein levels were tested through ELISA. Caspase-3 activity was used to determine apoptosis and was tested using flow cytometry. Results: The results indicated that curcumin had a cytotoxicity effect of 40.85 µg/mL. At concentrations of 40 µg/mL and 50 µg/mL, curcumin increases levels of protein RASSF1A (∆ = 26.53% and 47.35%, respectively), Bax (∆ = 48.79% and 386.15%), and caspase-3 (∆ = 1,678.51% and 1,871.889%) significantly. Conclusions: Curcumin exhibits anti-proliferative activity and apoptotic (Caspase-3) effects through activation of RASSF1A and Bax.
A fenda do gozo: uma leitura de O Caderno Rosa de Lori Lamby (1990), de Hilda Hilst, através da obra Le Plaisir du texte (1973), de Roland Barthes
Authors: Miotto Flávia Herédia
Published: December 2021

O artigo em questão se propõe a analisar O caderno rosa de Lori Lamby (1990), de Hilda Hilst, sob a luz das noções barthesianas presentes na obra O prazer do texto (1973). Mais especificamente, trabalharemos a noção de jouissance (gozo), a fim de verificar a hipótese de que a obra hilstiana se caracterizaria no que Barthes chamou de texte de jouissance (texto de gozo). A porosidade entre os seminários de Lacan e Barthes nos anos 1970 convoca-nos a nos debruçarmos sobre o conceito de gozo para Lacan e também sobre os seus primeiros contornos na obra freudiana. Finalmente, refletiremos sobre como o gozo se configura no texto de Hilst, de modo a questionar de que forma a linguagem erótica/pornográfica de que se utiliza corrobora para a potência da transgressão que visa inaugurar com a obra em questão. A proposta será arregimentada com os pressupostos teóricos de Sigmund Freud, Jacques Lacan, Georges Bataille, Eliane Robert Moraes, Alcir Pécora, Lúcia Castello Branco, entre outros. A pesquisa pretende-se, portanto, como uma contribuição aos estudos hilstianos e barthesianos no Brasil e na América Latina, revisitando suas obras e suscitando novas (e plurais) leituras acerca desses autores.
Autoria em regeneração: Barthes e o potencial da linguagem
Authors: Messias Carolina Augusto
Published: December 2021

Este artigo pretende investigar uma ética do “autorar” em Barthes, revisitando a questão da autoria através da narrativa do que se faz com a linguagem, para além de ler e escrever. O texto busca ler um Barthes autor como referência fundamental para pensar a regeneração do papel do autor na contemporaneidade. Nesse sentido, focam-se alguns fazeres narrados por Barthes como pesquisador, professor e escritor em suas produções textuais, para refletir sobre o potencial da linguagem em sua ética autoral.
O discursar intelectual em questão em A câmara clara
Authors: Oliveira Priscila Pesce Lopes de , Bylaardt Cid Ottoni
Published: December 2021

Este artigo examina relações de A câmara clara com diferentes tipos de saber e os parâmetros discursivos que os constituem, buscando no livro respostas barthesianas à questão de escrita “Como orientar as escolhas (de tema, de abordagem, de interlocutores, de referências, de gênero textual, de linguagem)?” Discute também a dimensão epistemológica e ética da adoção de uma pertença intermitente, preocupada com os valores efetivados nas escolhas de linguagem constituintes da atividade intelectual. Este texto propõe, sobretudo, mostrar que as inquietações de Barthes quanto à prática crítica e a alguns de seus parâmetros e pressupostos florescem em discussões epistemológicas, propostas teóricas e aspectos composicionais não ortodoxos, e demonstrar como elas afirmam, refutam e desviam traços e elementos modelares de discursividades ligadas ao Saber consagrado.
Uma arqueologia da impostura
Authors: Barbosa Marlon Augusto
Published: December 2021

O objetivo deste ensaio é mapear alguns territórios da crítica literária francesa e mostrar que, muitas vezes, esses territórios se transformam em verdadeiros campos de batalha. Reconstruir o conflito entre Roland Barthes e Raymond Picard, por exemplo, ajuda-nos a pensar que a crítica traz à tona uma certa resistência, entendida aqui a partir de uma dupla significação: como ato de resistir e como ato de reagir. Por um lado, o discurso crítico que deseja preservar uma continuidade a ser estabelecida entre as obras e os seus comentários e, por outro, uma tentativa de se refletir sobre a continuidade entre obra e comentário.
Barthes y el contrato: sexo, amistad, amor
Authors: Soto Luís G.
Published: December 2021

El filósofo francés Roland Barthes (1915-1980) propone el contrato como modo de regulación de las relaciones personales. Al especificar la forma y el contenido de cada relación, Barthes pretende evitar dos posiciones opuestas y extremas que distorsionan el intercambio: el egoísta, que toma y no da; el santo, que da y no pide. Ambas figuras bloquean o frustran la igualdad y la reciprocidad por las que se debe regir la interacción en las relaciones personales. Ahora bien, ¿de qué contrato o contratos se trata? y ¿cuáles serían sus características? En este trabajo, intentaremos responder a estas preguntas examinando tres tipos de relaciones, el sexo, la amistad y el amor, tal como aparecen en los escritos de Barthes. Contemplaremos estas cuestiones desde el punto de vista de la filosofía moral y pondremos el foco en los aspectos éticos y políticos.
Roland Barthes, adorável: disseminações de uma voz de autor
Authors: Carneiro Maria Clara da Silva Ramos , Nascimento Lauren Silva
Published: December 2021

Em seus cursos e textos, Roland Barthes descortinava a “cena da escritura”: a partir de uma seleção de textos apresentava a forma como determinadas figuras, palavras e vocabulários se atualizavam a cada texto, a cada contexto. Conhecido como o crítico que matou o Autor, Barthes também se inscreve como personagem de uma narrativa intelectual fascinante: nos últimos anos de vida, seu luto público pela morte da mãe e a disseminação de elementos de si em textos e aulas reverberaram como a escrita de um romance real, um romance perdido ou escondido que se confunde com seu pensamento crítico da literatura.
Barthes, Loyola, corpo
Authors: Samudio Jonas Miguel Pires , Pinto Carlos Rafael
Published: December 2021

Neste artigo, propomos investigar textos de Roland Barthes e de Inácio Loyola, sublinhando o significante corpo. Para isso, recorreremos a: Sade, Fourier Loyola (2005b), Fragmentos de um discurso amoroso (1989), Incidentes (1988), dentre outros textos, de Roland Barthes; Autobiografia (2005), Exercícios Espirituais (2009) e Diário espiritual (2007), de Inácio de Loyola; bem como a outros autores (BLANCHOT, 2010; CALVET, 1993; LIBANIO, 2010). Com nossa investigação, chegamos à compreensão de “corpo apaixonado”, entendido como o corpo da escritura afetado pelo corpo daquele que escreve, conforme dois biografemas destacados: a fratura e a interrupção.
Do sonho de Barthes ao impossível de ensinar
Authors: Almeida Antonio Alberto Peixoto de
Published: December 2021

Este trabalho tem como objetivo investigar a questão do ensino, em Lacan e Barthes, tomando como mote a ideia do enigma que envolve o sonho como um paradigma de experiência de linguagem. Para tanto, visa-se aí apontar como, desde a questão do impossível, é possível produzir algo em relação a isso, a partir da aproximação da noção de discurso analítico de Lacan com os escritos de Barthes sobre o tema. Para o estudo de Barthes, utiliza-se o conteúdo disponível de forma ampla, tanto os livros, quanto os cursos, tal como o material produzido pelos seus alunos e leitores, privilegiando o material que está mais acessível aos pesquisadores de Barthes no Brasil.
Babel, dispersão, inacabamento: a escrita de bordejar e o texto de fruição, uma escala de confluências entre Osman Lins e Roland Barthes
Authors: Rezende Luciana Barreto Machado
Published: December 2021

Em sua consciência acerca do ofício literário, as formulações ficcionais, as indagações filosóficas e as inovações estéticas adotadas pelo escritor pernambucano Osman Lins ao longo de toda sua obra, em especial no romance Avalovara (1973), coincidem com as proposições de Roland Barthes relativas ao “texto de fruição” – a provocar desestabilidade, desconforto, estado de perda e vacilação quanto às bases históricas, culturais e psicológicas do leitor. A assumida crise por parte do escritor e do leitor na relação com a linguagem e a representação é ilustrada neste artigo por meio do mito de Babel e os signos de infortúnio e incomunicabilidade que caracterizam a personagem alemã Roos em seu desencontro linguístico com o protagonista Abel da obra osmaniana. Edificada sob o propósito de alcançar o céu, a Torre de Babel é associada a desentendimento, desordem, dispersão, resultando em desventura, malogro e ruína. Ao lado de Roland Barthes, reflexões de Zumthor e Benjamin se fazem importantes para compreender a noção de inacabamento, confirmando como a linguagem se mostra falha e insuficiente. A partir do registro barthesiano de gozo e fruição, sublinhamos no romance em questão o tensionamento narrativo a partir de elipses sintáticas, esgarçamento textual, embaralhamento de fonemas e fusionamento de vocábulos.
Temporal Trends in Characteristics and Outcomes Associated With In‐Hospital Cardiac Arrest: A 20‐Year Analysis (1999–2018)
Authors: Wu Lingling , Narasimhan Bharat , Bhatia Kirtipal , Ho Kam S. , Krittanawong Chayakrit , Aronow Wilbert S. , Lam Patrick , Virani Salim S. , Pamboukian Salpy V.
Published: December 2021

Background

Despite advances in resuscitation medicine, the burden of in‐hospital cardiac arrest (IHCA) remains substantial. The impact of these advances and changes in resuscitation guidelines on IHCA survival remains poorly defined. To better characterize evolving patient characteristics and temporal trends in the nature and outcomes of IHCA, we undertook a 20‐year analysis of a national database.

Methods and Results

We analyzed the National Inpatient Sample (1999–2018) using
International Classification of Diseases
,
Ninth Revision
and
Tenth Revision, Clinical Modification
(
ICD‐9‐CM
and
ICD‐10‐CM
) codes to identify all adult patients suffering IHCA. Subgroup analysis was performed based on the type of cardiac arrest (ie, ventricular tachycardia/ventricular fibrillation or pulseless electrical activity‐asystole). An age‐ and sex‐adjusted model and a multivariable risk‐adjusted model were used to adjust for potential confounders. Over the 20‐year study period, a steady increase in rates of IHCA was observed, predominantly driven by pulseless electrical activity‐asystole arrest. Overall, survival rates increased by over 10% after adjusting for risk factors. In recent years (2014–2018), a similar trend toward improved survival is noted, though this only achieved statistical significance in the pulseless electrical activity‐asystole cohort.

Conclusions

Though the ideal quality metric in IHCA is meaningful neurological recovery, survival is the first step toward this. As overall IHCA rates rise, overall survival rates are improving in tandem. However, in more recent years, these improvements have plateaued, especially in the realm of ventricular tachycardia/ventricular fibrillation‐related survival. Future work is needed to better identify characteristics of IHCA nonsurvivors to improve resource allocation and health care policy in this area.
Aortic Stiffness, Pulse Pressure, and Cerebral Pulsatility Progress Despite Best Medical Management: The OXVASC Cohort
Authors: Webb Alastair J.S. , Lawson Amy , Wartolowska Karolina , Mazzucco Sara , Rothwell Peter M. ,   on behalf of the OXVASC Study Cohort
Published: December 2021

Background:

Increased cerebral arterial pulsatility is associated with cerebral small vessel disease, recurrent stroke, and dementia despite the best medical treatment. However, no study has identified the rates and determinants of progression of arterial stiffness and pulsatility.

Methods:

In consecutive patients within 6 weeks of transient ischemic attack or nondisabling stroke (OXVASC [Oxford Vascular Study]), arterial stiffness (pulse wave velocity [PWV]) and aortic systolic, aortic diastolic, and aortic pulse pressures (aoPP) were measured by applanation tonometry (Sphygmocor), while middle cerebral artery (MCA) peak (MCA-PSV) and trough (MCA-EDV) flow velocity and Gosling pulsatility index (PI; MCA-PI) were measured by transcranial ultrasound (transcranial Doppler, DWL Doppler Box). Repeat assessments were performed at the 5-year follow-up visit after intensive medical treatment and agreement determined by intraclass correlation coefficients. Rates of progression and their determinants, stratified by age and sex, were determined by mixed-effects linear models, adjusted for age, sex, and cardiovascular risk factors.

Results:

In 188 surviving, eligible patients with repeat assessments after a median of 5.8 years. PWV, aoPP, and MCA-PI were highly reproducible (intraclass correlation coefficients, 0.71, 0.59, and 0.65, respectively), with progression of PWV (2.4%;
P
<0.0001) and aoPP (3.5%;
P
<0.0001) but not significantly for MCA-PI overall (0.93;
P
=0.22). However, PWV increased at a faster rate with increasing age (0.009 m/s per y/y;
P
<0.0001), while aoPP and MCA-PI increased significantly above the age of 55 years (aoPP,
P
<0.0001; MCA-PI,
P
=0.009). Higher aortic systolic blood pressure and diastolic blood pressure predicted a greater rate of progression of PWV and aoPP, but not MCA-PI, although current MCA-PI was particularly strongly associated with concurrent aoPP (
P
<0.001).

Conclusions:

Arterial pulsatility and aortic stiffness progressed significantly after 55 years of age despite the best medical treatment. Progression of stiffness and aoPP was determined by high blood pressure, but MCA-PI predominantly reflected current aoPP. Treatments targetting cerebral pulsatility may need to principally target aortic stiffness and pulse pressure to have the potential to prevent cerebral small vessel disease.
At the Margins of the State
Authors: Sahoo Sarbeswar
Published: December 2021

How is Pentecostalism changing the notions and experiences of citizenship at the margins of the state? Addressing this question, the paper argues that in the context of south Rajasthan, the Pentecostal church has played a vital role in combining the values of both pedagogical and governmental paradigms of citizenship not just to fill in the absence of the state but also to create an alternative model of citizenship that goes beyond the mere political rights. This alternative model of ‘Christian citizenship’ has effectively combined development with Pentecostal moral values. Furthermore, the Pentecostal church, by acting as a pedagogical agent, by organising active social ministries, and by developing ethical subjectivities among the Bhils, has engendered new notions of agency, autonomy and citizenship at the margins of the state.