bluuebunny/crossref_metadata_2025 huggingface dataset:
Ecological Efficiency Evaluation and Development Trend Prediction of Marine Aquaculture Industry: A Case Study of Weihai City, China
Authors: Wu Yinuo , Zhong Changbiao , Wu Yanyi
Published: January 2025

The marine aquaculture industry holds a significant position in the development of Weihai City’s fishing industry, with its ecological efficiency having a direct impact on the sustainable progress of the regional fishing sector. Utilizing a three-stage DEA model as an unexpected output model, this study systematically assessed the ecological efficiency of Weihai City’s marine aquaculture industry. By employing kernel density estimation, we analyzed the temporal dynamic evolution of ecological efficiency within the marine aquaculture industry. The results indicate that the overall ecological efficiency of marine aquaculture in Weihai City has improved to some extent, influenced by environmental factors such as government support, urbanization level, and regional economic development level. After removing environmental and random factors, it was found that the overall ecological efficiency of the marine aquaculture industry in Weihai City shows a more stable upward trend. Furthermore, using a gray dynamic model, GM (1, 1), we predicted the trend of ecological efficiency in the marine aquaculture industry. The findings indicate that, with the progressive adoption of advanced aquaculture technologies, the ecological efficiency of Weihai City’s marine aquaculture is anticipated to continue growing in the future. However, the pace of growth has decelerated. To maximize ecological efficiency, it is imperative to optimize resource allocation, foster technological innovation, and elevate awareness regarding ecological and environmental preservation. By assessing the ecological efficiency of Weihai City’s marine aquaculture industry, this article aims to shed light on the industry’s progress, thereby promoting its high-quality and sustainable development.
Identification of Potential Therapeutic Targets Against Anthrax-Toxin-Induced Liver and Heart Damage
Authors: Wu Lihong , Chen Yanping , Yan Yongyong , Wang Haiyan , Guy Cynthia D. , Carney John , Moreno Carla L. , Quintanilla-Arteaga Anaisa , Monsivais Fernando , Zheng Zhichao , Zeng Mingtao
Published: January 2025

Anthrax represents a disease resulting from infection by toxin-secreting bacteria, Bacillus anthracis. This research aimed to identify new therapeutic targets to combat anthrax. We performed assays to assess cell viability, apoptosis, glycogen consumption, and compound uptake and release in hepatocytes and cardiomyocytes responding to anthrax toxins. Microarray analysis was carried out to identify the genes potentially involved in toxin-induced toxicity. Knockdown experiments were performed to validate the contributions of the identified genes. Our study showed that anthrax edema toxin (EdTx) and lethal toxin (LeTx) induced lethal damage in mouse liver and heart, respectively. Microarray assays showed that 218 genes were potentially involved in EdTx-mediated toxicity, and 18 genes were potentially associated with LeTx-mediated toxicity. Among these genes, the knockdown of Rgs1, Hcar2, Fosl2, Hcar2, Cxcl2, and Cxcl3 protected primary hepatocytes from EdTx-induced cytotoxicity. Plasminogen activator inhibitor 1 (PAI-1)-encoding Serpine1 constituted the most significantly upregulated gene in response to LeTx treatment in mouse liver. PAI-1 knockout mouse models had a higher tolerance to LeTx compared with wild-type counterparts, suggesting that PAI-1 is essential for LeTx-induced toxicity and might represent a therapeutic target in LeTx-induced tissue damage. These results provide potential therapeutic targets for combating anthrax-toxin-induced liver and heart damage.
Gene Expression Signatures of Porcine Bone Marrow-Derived Antigen-Presenting Cells Infected with Classical Swine Fever Virus
Authors: Coronado Liani , Wang Miaomiao , Bohórquez Jose Alejandro , Muñoz-Aguilera Adriana , Alberch Mònica , Martínez Patricia , Ruggli Nicolas , Ramayo-Caldas Yuliaxis , Ganges Llilianne
Published: January 2025

For a better understanding of classical swine fever (CSF) pathogenesis, a transcriptomic analysis was performed using porcine bone marrow (BM)-derived antigen-presenting cells (APCs) infected ex vivo with two different cDNA-derived classical swine fever virus (CSFV) strains, the low-virulence Pinar de Rio (vPdR-36U) or the lethal vPdR-H30K-5U. The transcriptomic profile of vPdR-36U- or vPdR-H30K-5U-infected versus noninfected cells revealed 946 and 2643 differentially expressed genes (DEGs), respectively. The upregulation of ISG15, CXCL-10, ADAM8, and CSF1 was found after infection with vPdR-36U, which could contribute to the generation of mild CSF forms. In contrast, cells infected with the lethal vPdR-H30K-5U overexpressed the immune checkpoint molecules PD-L1, CD276, and LAG3, which are involved in T-cell exhaustion and could be associated with adaptive immunity impairment. vPdR-H30K-5U also induced increased expression of PPBP, IL-8, IL-6, ECE1, and Rab27b, which are mediators of inflammatory responses that can be involved in cytokine storms. The TNF signaling pathway, which is related to the activation and proliferation of different subsets of immune cells, including CD4+ T cells, was notably upregulated in response to the low-pathogenicity virus. The Th17, Th1, and Th2 differentiation pathways were downregulated by the highly pathogenic virus only, supporting the role of T-cell-mediated immunity in protecting against CSFV.
A Comprehensive Review of Antiviral Therapy for Hepatitis C: The Long Journey from Interferon to Pan-Genotypic Direct-Acting Antivirals (DAAs)
Authors: Di Marco Lorenza , Cannova Simona , Ferrigno Emanuele , Landro Giuseppe , Nonni Rosario , Mantia Claudia La , Cartabellotta Fabio , Calvaruso Vincenza , Di Marco Vito
Published: January 2025

The treatment landscape for hepatitis C virus (HCV) infection has transformed over the past few decades, evolving from the limited efficacy of interferon (IFN) monotherapy to the highly successful pan-genotypic direct-acting antivirals (DAAs) used today. Initially, alpha-interferon monotherapy, introduced in the 1990s, was the standard treatment, yet it provided low sustained virological response (SVR) rates and caused significant adverse effects, limiting its utility. The development of pegylated interferon (peg-IFN) improved the pharmacokinetic profile of IFN, allowing for less frequent dosing and modestly improved response rates. When combined with ribavirin, peg-IFN achieved higher SVR rates, especially in non-genotype 1 HCV infections, but the combination also brought additional side effects, such as anemia and depression. The advent of the first-generation DAAs, such as telaprevir and boceprevir, marked a significant milestone. Combined with peg-IFN and ribavirin, these protease inhibitors boosted response rates in patients with genotype 1 HCV. However, high rates of adverse effects and drug resistance remained challenges. Second-generation DAAs, like sofosbuvir and ledipasvir, introduced IFN-free regimens with improved safety profiles and efficacy. The most recent advances are pan-genotypic DAAs, including glecaprevir-pibrentasvir and sofosbuvir-velpatasvir, which offer high SVR rates across all genotypes, shorter treatment durations, and fewer side effects. Current pan-genotypic regimens represent a cornerstone in HCV therapy, providing an accessible and effective solution globally.
Impact of Grass Carp and Crucian Carp on Submerged Macrophyte and Phosphorus Cycling in Shallow Lake Mesocosms
Authors: Chen Xin , Wu Weiju , Ao Hongyi , Hu Shenghua , Chen Huaqiang , Chen Xiaofei , Wu Chenxi
Published: January 2025

Submerged macrophytes are essential for the restoration of shallow lakes for maintaining clear-water conditions. The presence of fish can affect the nutrient cycles and the growth of submerged macrophytes in lakes. In this study, a 28-day mesocosm experiment was carried out with an herbivorous fish Ctenopharyngodon idella (CID) and an omni-benthivorous fish Carassius auratus (CAU) to investigate their effects on the growth of a submerged macrophyte Hydrilla verticillata and phosphorus (P) cycle in shallow lakes. The results showed that CID slowed down the growth of H. verticillata while CAU showed no significant effect. In overlying water, CID only increased the ammonium nitrogen (NH3-N) concentration in the later stage due to excretion, while CAU elevated particulate phosphorus (PP) levels during the experiment through disturbance. Meanwhile, the radial oxygen loss and photosynthesis of H. verticillata in CAU might promote the formation of NaOH-P and HCl-P in the sediment, respectively. Changes in the water and sediment properties caused by CID and CAU can contribute to the increase in the eutrophication risk index (ERI). Our findings suggest that CID has the potential to be an indirect biological manipulation tool, while CAU should be controlled to minimize its negative impacts on the P cycle in lakes.
Rethinking Indigenous Community-Led Water Sustainability: Decolonial and Relational Approaches in Western Canada
Authors: Datta Ranjan , Chapola Jebunnessa , Lewis Kevin
Published: January 2025

This study examines Indigenous community-led water sustainability in Western Canada through relational and decolonial lenses, addressing the interplay between traditional knowledge, environmental governance, and cultural identity. The relational and decolonial frameworks emphasize water as a living entity integral to environmental sustainability and community well-being, contrasting with extractive Western models that prioritize economic gains. Using a community-led collaborative methodology, the research engaged Elders, Knowledge-keepers, and youth in discussions and land-based activities, reinforcing intergenerational knowledge transfer. The findings showcase critical challenges to Indigenous water governance, including industrial encroachments, climate change, and colonial environmental management systems that marginalize Indigenous perspectives. These human-created challenges threaten Indigenous water quality and disrupt Indigenous sustainable governance, underlining the need for alternative, adaptive frameworks. Despite these challenges, Indigenous communities are reclaiming water sustainability through initiatives that implement traditional knowledge, cultural revitalization, and collaborative governance models. Such efforts emphasize respect, reciprocity, and stewardship, promoting long-term environmental sustainability.
Intubation amidst COVID-19: how mask protocols and communication impact SARS-CoV-2 transmission among medical staff
Authors: Thu Le Thi Anh , Nguyen Tuan , Minh Tri Nguyen , Thi The La , Thuy Dung Nguyen Thi , Nguyen Thien Minh
Published: January 2025

Objective: To describe the sequence of (Severe acute respiratory syndrome corona virus 2) infection following endotracheal intubation in Coronavirus disease 2019 patients.
Design: A retrospective case series study. This analysis focuses on cases involving hospital medical staff who contracted SARS-CoV-2 after performing endotracheal intubation on a COVID-19 patient on August 2, 2021, at Hoan My Thu Duc Hospital, a private hospital treating COVID-19 patients in Vietnam. The participants were 13 medical staff members involved in aerosol-generating procedures.
Results: The infection spread to eight healthcare workers directly involved in emergency intubation. Five were suspected of contracting SARS-CoV-2 immediately following the emergency treatment of COVID-19 patients, and three were infected via transmission from their colleagues. The improper fit of N95 masks and failure to wear them during interpersonal communication were identified as significant risk factors.
Conclusions: The research underscores the critical need for proper N95 mask fit during aerosol-generating procedures. Healthcare professionals treating COVID-19 patients must consistently use masks when communicating with colleagues, even outside of work hours, to curb the spread of SARS-CoV-2 among medical staff.
Estado Epiléptico Mioclônico: raro diagnóstico dentro dos estados de mal convulsivos, diferenças no tratamento e prognóstico em 4 casos
Authors: Souza Lorraine Alves de , Valadão Kesllin Mariane Gomes , Rahal Márcio
Published: January 2025

O Estado Epiléptico Mioclônico é um período prolongado de espasmos mioclônicos, após 30 minutos. Aqui são descritas características clínicas, registros de eletroencefalografia de quatro pacientes nesta condição. O Estado Epiléptico Mioclônico foi descrito em doenças neurodegenerativas, síndromes epilépticas generalizadas, estados metabólicos tóxicos e após lesão cerebral de anóxica. Em pacientes sem histórico de epilepsia, o Estado Epiléptico Mioclônico raramente foi relatado como relatos de casos únicos, que estavam principalmente relacionados ao medicamento. Entre 2017 e 2023, três pacientes do sexo masculino e um do sexo feminino, três com anóxia prévia e um com epilepsia prévia foram internados e tratados. A idade variou entre 39 e 84 anos. Com o tratamento com fenitoína, três pacientes pioraram ou iniciaram Estado Epiléptico Mioclônico. O agravamento da epilepsia generalizada idiopática ou a precipitação do Estado Epiléptico Mioclônico foram bem documentados na Epilepsia Generalizada. Portanto, apenas um paciente desses casos tinha Epilepsia Mioclônica Juvenil. Os pacientes melhoraram ou controlaram as convulsões e a mioclonia com a retirada da fenitoína. O prognóstico foi ruim, dois morreram, dois sobreviveram. O objetivo deste estudo é uma série de casos de 4 pacientes que relatam Estado Epiléptico Mioclônico. Três pacientes com piora clínica de mioclonia ou precipitação de Estado Epiléptico Mioclônico após uso de fenitoína para estado de mal epiléptico.
A residência pedagógica e as contribuições para a formação docente / Pedagogical residency and the contributions to teacher education
Authors: Krzyzanowski Gabriela Pereira , Lehmkuhl Olga Maria , Dos Santos Rafaela Pinheiro , Da Silva Diogo , Selli Melz Elisângela Regina , Rosa Reinert Scheila Priscila
Published: January 2025

O Programa de Residência Pedagógica (RP) é voltado para os cursos de licenciatura e contribui para a formação da prática docente dos acadêmicos. Cada núcleo procura adequar seu plano de atividades para que atenda os objetivos do programa. Neste relato apresentamos as temáticas abordadas e discutidas no núcleo de RP em matemática do Instituto Federal Catarinense (IFC) - Campus de Rio do Sul, além de algumas das ações desenvolvidas durante o Módulo II. Dentre elas, destacamos a participação de convidados, especialistas que levaram os(as) residentes a reflexões sobre algumas temáticas relevantes para a educação Matemática, como: Matética, Feiras de Matemática, Tecnologias Digitais, História da Matemática, Etnomatemática, Resolução de Problemas, Educação e Sociedade, Modelagem Matemática e Laboratório de Educação Matemática. Discorremos a respeito das vivências que aconteceram durante os encontros e as contribuições para os envolvidos no programa. Concluímos que a RP contribui com o processo de formação teórica e com a prática docente, oferecendo elementos fundamentais para a dinâmica da sala de aula ao abordar temas e recursos diversificados, além de reflexões acerca de que tipo de professor/educador os(as) residentes almejam se tornar e, acredita-se que as atividades desenvolvidas ao longo do programa moldaram a concepção epistemológica dos residentes, futuros professores.
Equidade no acesso ao rastreamento mamográfico do câncer de mama com intervenção de mamógrafo móvel no estado do Piauí
Authors: Dantas Yara Dahane de Carvalho Paixão , Silva Filho Wilson Seraime da
Published: January 2025

O câncer de mama é uma das principais causas de mortalidade feminina no mundo, sendo um grave problema de saúde pública. A detecção precoce, por meio do rastreamento mamográfico, é reconhecida como uma estratégia essencial para reduzir a mortalidade e melhorar a qualidade de vida das pacientes. No entanto, a acessibilidade a exames mamográficos é frequentemente limitada em regiões menos desenvolvidas, como o estado do Piauí. Nesse contexto, a utilização de mamógrafos móveis surge como uma solução inovadora e eficaz para superar barreiras geográficas e socioeconômicas. Dessa forma, o presente trabalho tem como objetivo analisar o impacto do uso de mamógrafos móveis no estado do Piauí na promoção da equidade no acesso ao rastreamento mamográfico, identificando suas potencialidades como ferramenta para reduzir disparidades regionais e socioeconômicas. Conclui-se que, o uso de mamógrafos móveis no Piauí é um exemplo prático de como a inovação em saúde pode transformar realidades desafiadoras e oferecer soluções acessíveis para problemas complexos. Este estudo contribui para ampliar o conhecimento sobre o impacto dessa iniciativa e aponta caminhos para futuras melhorias. Ao integrar práticas inovadoras, gestão eficiente e a perspectiva das usuárias, o programa tem o potencial de se tornar uma referência nacional no combate ao câncer de mama, reafirmando o compromisso com a saúde e o bem-estar da população feminina.
Relato de caso – caso de comunicação interatrial e forame oval patente em paciente jovem
Authors: Rodolfo Raquel Lima
Published: January 2025

O presente trabalho tem o objetivo de descrever o caso clínico de uma paciente jovem portadora de comunicação interatrial tipo ostium secundum juntamente com forame oval patente e discorrer acerca das características sobre essas duas afecções, tais como anatomia, definição, diagnóstico e abordagem terapêutica. Para realização do presente estudo foram utilizados revisão de prontuário e revisão de literatura para expor as principais informações. A comunicação interatrial representa em torno de 6 a 10% das cardiopatias congênitas, enquanto o forame oval patente é mais comum e pode ser encontrada em cerca de 30% da população. Ambas são cardiopatias congênitas passíveis de tratamento percutâneo.
Posterior disc displacement: reviewing the concept of reduction and non-reduction
Authors: Prado Gabriela Dias , Simões Hannah Barros , Nascimento Ana Carla de Souza , Dantas Janaina Araújo , Cangussu Maria Cristina Teixeira , Campos Paulo Sérgio Flores
Published: January 2025

Background: Posterior disc displacement of the temporomandibular joint (TMJ) has been described before as a rare condition. Among the types of disc displacements previously described in the literature, Posterior disc displacement imaging characteristics still need to be further studied. Clinical presentation: We hereby present two clinical cases, with a more coherent and objective classification of posterior displacement with reduction, partial reduction, and without reduction of the articular disc of the temporomandibular joint. Clinical relevance: The cases here presented our concept of reduction, partial reduction and non-reduction of the articular disc for cases of primary and true Posterior disc displacement.
El mapudungun, interculturalidad e inclusiva en el sistema educativo chileno
Authors: Tom José Manuel Salum
Published: January 2025

El mapudungun es uno de los patrimonios que define la identidad del pueblo mapuche. Su sobrevivencia a través del tiempo se debe, principalmente, a los procesos de re-etnificación ocurridos en la última década. No obstante, es necesario seguir las estrategias desarrolladas brevemente en este trabajo, con la finalidad de mantener su vigencia y revitalización en el contexto sociocultural chileno. Un programa de mantención de esta lengua indígena debe tener el debido respaldo estatal para convertirse en una lengua saludable y autosuficiente. Todo esto permitirá la continuación del modo de vida de sus usuarios, así como el reflejo fiel de su cultura dentro del mundo multicultural.
Obtenção de bio-óleos para avaliação da atividade fitotóxica
Authors: Campolina Sophia Gonçalves , Araújo Vívian Helene Diniz , Leite Brenno Santos , Santos Leandro José Dos , Leite Sibele Augusta Ferreira
Published: January 2025

O aumento na produção e consumo de café e abacate no Brasil gera uma quantidade significativa de resíduos, como a borra de café e os caroços de abacate. Esses subprodutos lignocelulósicos, muitas vezes descartados, contêm em sua estrutura moléculas com potencial para diversas aplicações, como bioherbicidas e repelentes. Este estudo investiga o uso de duas rotas na produção de bio-óleos, a extração e a liquefação, avaliando os produtos desses processos e seu potencial fitotóxico para uso como herbicidas naturais. A extração foi realizada por meio dos métodos Soxhlet e liquefação em autoclave, seguida de testes de densidade, viscosidade e germinação de sementes de pepino. Os resultados indicam que os bio-óleos extraídos apresentam propriedades promissoras para o controle sustentável de plantas daninhas, reforçando a importância das biorefinarias na valorização de resíduos agrícolas e na redução da dependência de herbicidas sintéticos.
MULTINATIONALS AND THE STATE OF CIVIL LIBERTIES AND POLITICAL RIGHTS IN ASIA
Authors: Shah Mumtaz Hussain , Tahir Shandana
Published: January 2025

This research paper analyses the possible influence of political rights and civil liberties in Asian developing host economies on the foreign direct investment (FDI) decision of the multinationals from the developed source nations. Generally, United States, European Union and Japan are considered as the primary sources of FDI. All of them locally have very high standards of political rights and civil liberties. Their societies are extremely sensitive for the respect of personal choice and freedom to express oneself. The current study tries to ascertain that whether the existence of a better set of the same principles have any effect on the investors of these countries. Utilising annual data of twenty six developing states from Asia for twenty one years, it is found through random effects panel technique that political rights significantly influence the investors’ location choice in overseas markets as a possible long-term host to their investment. However, contrary to expectations civil liberties have a negative sway, though the effect is insignificant. The conventional FDI location drivers such as market size, development level, extent of economic liberalisation continues to significantly affect multinationals.
Инновационные подходы и методы бюджетирования и их использование при построении эффективной системы мотивации персонала
Authors: Фатеева С.В. , Семенов С.Н.
Published: January 2025

Принятие решения о внедрении бюджетирования это серьезный шаг к новой модели управления компанией. Последовательность этапов, выбор методов и механизм бюджетирования для каждой компании должен быть сугубо индивидуален. Особую ценность данный тезис приобретает при построении эффективной системы мотивации. Основная роль в данном построении принадлежит ИТсистемам. В данной статье представляется обоснование основных этапов при построении системы бюджетирования во взаимосвязи с системой Key Performance Indicators. При этом отмечается, что основные подходы при построении системы бюджетирования остаются одинаковыми. Основная задача руководителя компании избрать истинный подход. Также необходимо обратить внимание на различные факторы, которые оказывают влияние на связи между системой бюджетирования и на ее основе выстроенной системы мотивации.

the decision on the implementation of budgeting is a serious step towards a new model of company management. The sequence of stages, the choice of methods and the mechanism of budgeting for each company should be purely individual. Of particular value this thesis acquires in the construction of an effective system of motivation. The main role in this construction belongs to it systems. This article presents the rationale for the main stages in the construction of the budgeting system in conjunction with the system Key Performance Indicators. It is noted that the main approaches in the construction of the budgeting system remain the same. The main task of the head of the company is to choose the true approach. It is also necessary to pay attention to the various factors that affect the relationship between the budgeting system and the motivation system built on its basis.
Система бухгалтерского учета в торговой сфере и инвентаризация готовой продукции
Authors: Исраилова З.Р. , Мациева М.Л.-А.
Published: January 2025

в данной статье рассмотрена система бухгалтерского учета в предприятиях торговой сферы. Раскрыты некоторые аспекты сущности торговой деятельности. Изучен процесс проведения инвентаризационной проверки готовой продукции в торговом предприятии и описаны схематично пути отражения результатов ее в бухгалтерском учете.

this article discusses the accounting system in the enterprises of the trade sector. Revealed some aspects of the essence of trading activities. The process of carrying out an inventory check of finished products in a commercial enterprise has been studied and schematically described are ways of reflecting its results in accounting.
Роль финансовой отчетности производственного предприятия при оценке рисков и угроз внешнеэкономической деятельности
Authors: Харитонова В.В. , Биктемирова М.Х.
Published: January 2025

Нестабильная финансовая среда, в которой все чаще находятся предприятия страны, подталкивает хозяйствующие субъекты к ведению осторожного бизнеса, считая каждый шаг до мелочей. Для этого руководство предприятия вынуждено хотя бы периодически проводить оценку рисков, находить эффективные решения проблем, а также уметь правильно прогнозировать изменения рыночной системы и внешнеэкономической деятельности. Уровень экономической безопасности является одним из ключевых показателей инвестиционной привлекательности и надежности производственного предприятия, это характеристика его жизнеспособности. Эта категория особенно важна в тех отраслях, которые считаются проблемными или переживают кризис.

The unstable financial environment in which the countrys enterprises are increasingly located pushes economic entities to conduct cautious business, counting every step to the smallest detail. To do this, the companys management is forced to at least periodically assess risks, find effective solutions to problems, and be able to correctly predict changes in the market system and foreign economic activity. The level of economic security is one of the key indicators of investment attractiveness and reliability of the production enterprise, it is a characteristic of its viability. This category is especially important in those industries that are considered problematic or experiencing a crisis.
Фразеологическая картина мира.
Authors: Алишова М.К.
Published: January 2025

Целью научной статьи является обнаружение специфики во фразеологической картине сопоставляемых языков кыргызских и английских, общих и различных, национальнокультурных особенностей, а также выявить лингвокультурологические особенности ФЕ, раскрыть специфику фразеологической картины мира в кыргызских и английских языках в эпосе Манас .

The purpose of the scientific article is to identify the specifics in the phraseological picture of the comparable languages of Kyrgyz and English, common and different, national and cultural characteristics, as well as to identify the linguoculturological features of the phraseological units, to reveal the specifics of the phraseological picture of the world in Kyrgyz and English in the epic Manas.
The possibilities of ultrasound diagnostics in assessing the structural variants of the bifurcation of the common carotid artery
Authors: Moshkin Andrey , Nikolenko Vladimir N. , Khalilov Maksud A. , Gavrushova L. V , Moshkina Lubov V. , Li Zhi
Published: January 2025

Aim - to study age–related features to identify different structural variants of the common carotid artery bifurcation using ultrasound imaging.
Materials and methods. A survey include of 1,061 volunteers (57.0±10.7 years old). The results were grouped according to age and gender, and statistically processed.
Results. 2,122 vascular complexes were studied (1,396 in women and 726 in men). There are 5 main types formed. Types A and B prevailed (up to 42% type A). Type B is up to 35% among men, 27% among women. Type B is up to 19% among women, and in men in 15% of cases. Other options were 4-7%. When dividing the participants based on gender and age, 4 groups of observation participants were formed. Type A among women in all groups was 41-43%, for men the frequency of this variant was 31-40%. For men, the highest detection of type B was noted in the first age group – 48%. Type B was determined in groups 1-3 2-4% more often among women, and in group 4 more often among men – 31%. The highest values for type D were noted in the group of men - 12% in the 4th age group, in other cases, types D and D in most cases are 4-7%.
Conclusions. As a result, the predominance of type A among women was noted. Types A and B were more often identified among all participants. Type B was often found in young men. There has been an increase in the diagnosis of type B with age. Rare variants accounted for 4-7% of cases. The study of the variable anatomy of the main arteries of the neck makes it possible to develop personalized directions in the treatment of vascular diseases and improve minimally invasive surgical interventions.
O EXERCÍCIO DA PSICOLOGIA EM INSTITUTOS FEDERAIS DE EDUCAÇÃO, CIÊNCIA E TECNOLOGIA
Authors: Petracco Milene Mabilde , Hamann Cristiano , Pizzinato Adolfo
Published: January 2025

This article discusses the role of Psychology as a strategic role in institutional performance in interface with education, having as a starting point the work carried out on one of the campuses of the Federal Institute of Scientific and Technological Education Sul-rio-grandense (IFSul). The research, carried out in an ethnographic perspective, contoured with the monitoring of the daily institutional work and group interventions with students, processes investigated from perspectives of Discourse Analysis. As a result, an analytical axis proved to be a professional and interventional challenge: “student success” as a capitalist-technical statement of the educational process. Derived from this, three others appear as strategic for the exercise of Psychology: the non-bureaucratization of work; the distribution of organizational priorities; psychological demands as associated with the exercise of citizenship. In a context of technicist co-option, Psychology proves to be fundamental for the understanding of institutional rationalities and the production of singularity, being, potentially, in partnership with other professionals and students.
O PROCESSO DE CONSTRUÇÃO DA PERMANÊNCIA DOS TRABALHADORES-ESTUDANTES
Authors: Carvalho Gisele Francisca da Silva Carvalho , Barros Leandro Eduardo Vieira , Ribeiro Mariana Sampaio , Tito Luiz Filipe de Souza
Published: January 2025

The aim of this article is to present and discuss four social markers that make up the construction of the permanence of working students enrolled in night school, technical and higher education: age, city of residence, type of employment relationship, and remuneration. From the data of a survey, two statistical techniques were used to support the analysis: the chi-square test and the correspondence analysis. The results indicated associations between variables that revealed non-linear conditioning to which student workers are submitted and that constitute the daily production of student permanence. We conclude that knowledge about these associations can support and guide the elaboration of institutional policies for permanence in its broadest sense.
Prolegómenos a una semiótica cognitiva
Authors: Morales Campos Arturo
Published: January 2025

El presente trabajo trata de ser una contribución a la semiótica cognitiva, en particular, y a las ciencias cognitivas, en general. El aporte radica en exponer una definición de semiosis que integre aspectos biológicos y, a la vez, culturales de un sujeto cognoscente (para nosotros, humano). Por lo tanto, será más pertinente llamarla “biosemiosis”. Como objetivo secundario, buscamos que la semiótica cognitiva, después de hacerse de conceptos pertinentes y propios, sea una más de las disciplinas que componen las ciencias cognitivas. En este sentido, el escrito parte de determinadas nociones de la semiótica general, obviamente, pero, además, de las neurociencias y de la biología. Hacemos, pues, una especie de amalgama inter y transdisciplinar que gira en torno de la semiosis como proceso biocognitivo complejo y material.
Líneas de recepción y crítica de la filosofía kantiana en la filosofía en lengua alemana en el siglo XXI
Authors: Leyva Martínez Gustavo
Published: January 2025

Conmemoración: Immanuel Kant 1724 – 1804
Methane-filled hollow fiber: a cost-effective pathway to compress high repetition rate ytterbium femtosecond lasers using self-phase modulation
Authors: Kumar Mayank , Guay Tristan , Ibrahim Heide , Légaré François
Published: January 2025

Hollow-core fiber (HCF) based temporal pulse compression is widely used to generate few-cycle pulses. Here, we demonstrate the strength of methane (CH4) as a nonlinear medium for HCF-based pulse compressors to achieve high average power few-cycle pulses of sub-16 fs duration with >70% transmission and up to 250 kHz repetition rate in a compact setup and present it as a cost-effective alternative to highly expensive and scarcely available noble gases.
The Preventive Health Professions and their knowledge on the REACh topic: A preliminary investigation among S.It.I. members
Authors: Dalena Annamaria , Rizzi Roberto , Surace Fabio , Campigotto Igor , Colucci Gianni , Mazzurana Mirko , Miceli Stefano , Del Bianco Flavio , Di Fant Marcella , Marzocca Piersaverio , Salerno Fabiana , Lanzilotti Carola , Cambria Roberta , Nigro Maria , Marcotrigiano Vincenzo
Published: January 2025

Chemical risk is a debated topic in the services of the Italian Prevention Departments, as it is a matter that cuts across many settings. Through a survey jointly promoted by the Task Shifting Working Group and the Healthcare Professions Council of the Italian Society of Hygiene, Preventive Medicine, and Public Health (S.It.I), this study investigates the knowledge and the application level of the REACh issue and discusses the reference regulatory setting with a view to developing and enhancing the skills of healthcare workers who, within their professional activity, deal with this transversal topic daily.
VIRTUAL TOUR PENGENALAN LINGKUNGAN KAMPUS UNIVERSITAS KRISTEN INDONESIA MALUKU
Authors: Siwalette Reynaldi , Tomasila Golda , Rahimu Ode Darmayanti
Published: January 2025

Perkembangan teknologi yang terjadi di era sekarang ini memungkinkan seseorang dapat menjelajahi suatu tempat tanpa perlu datang langsung ke tempat tersebut. Teknologi ini disebut virtual tour. Virtual tour merupakan sebuah simulasi dari suatu tempat yang terdiri atas foto maupun video. Penelitian yang dilakukan ini bertujuan untuk membangun sebuah virtual tour pada Universitas Kristen Indonesia Maluku (UKIM). Ini penting dilakukan dalam upaya memperkenalkan dan mempromosikan lingkungan kampus UKIM juga secara virtual sebagai salah satu universitas swasta di Kota Ambon. Penelitian ini menggunakan Metode Waterfall sebagai acuan dalam mengembangkan teknologi virtual tour. Pengujian sistem dilakukan dengan 2 (dua) cara yaitu: (1) Pengujian usability (kegunaan) dengan Use Questionare yang menunjukkan hasil kelayakan kegunaan sistem sebesar 82,83%, (2) Pengujian Blackbox yang menunjukkan keseluruhan fitur pada sistem telah berfungsi dengan baik.  Penelitian ini diharapkan dapat memberikan dampak positif dalam hal mempromosikan lingkungan kampus UKIM secara virtual.
RANCANGAN SISTEM PEMINJAMAN BARANG DIGITAL BERBASIS WEB
Authors: Nabilah M. Zakki , Aziz Ramadhani Abdul , Ilmy Nazzarin Ziddan , Anastasya Amanda , Butsainah Nazifah , Angelia Sebayang Fransisca
Published: January 2025

Di era digitalisasi, pergeseran sistem peminjaman dari metode manual ke digital telah menjadi solusi yang signifikan dalam meningkatkan efisiensi operasional. Jurusan Teknologi Informasi di Politeknik Negeri Samarinda (POLNES) menghadapi kebutuhan yang tinggi terkait peminjaman barang, namun sistem manual yang ada saat ini menunjukkan sejumlah keterbatasan, antara lain pencatatan yang tidak akurat, pengelolaan data yang kurang efisien, dan risiko kehilangan aset. Penelitian ini bertujuan untuk merancang dan mengimplementasikan sistem peminjaman barang berbasis web yang dapat meningkatkan efisiensi di lingkungan jurusan tersebut. Dengan memanfaatkan teknologi web modern dan pendekatan yang ramah pengguna, sistem ini diharapkan dapat memudahkan proses peminjaman. Hasil dari implementasi sistem ini diprediksi mampu meningkatkan efisiensi proses hingga 60% dibandingkan dengan metode manual yang sebelumnya digunakan
ANALISIS PENGGUNAAN BLOCKCHAIN UNTUK PENGELOLAAN DI BIDANG PENDIDIKAN
Authors: Pribadi Fitrian Harry , Andriyani Nita , Anggraeni Chica , Fajri Ashofwani Muhammad , Muftiana Miftah Adhfar
Published: January 2025

Penerapan teknologi blockchain di sektor pendidikan menawarkan solusi untuk masalah yang sering dihadapi, seperti kurangnya transparansi, pemalsuan ijazah, dan manajemen data akademik yang tidak efisien. Dengan karakteristik desentralisasi, transparansi, dan imutabilitas, blockchain dapat mengatasi tantangan dalam administrasi pendidikan, seperti verifikasi ijazah dan pengelolaan portofolio digital. Penelitian ini bertujuan untuk menganalisis potensi penerapan teknologi blockchain dalam meningkatkan kualitas dan efisiensi sistem pendidikan. Metode yang digunakan adalah studi literatur dari berbagai penelitian sebelumnya mengenai penggunaan blockchain dalam pendidikan. Hasil penelitian menunjukkan bahwa teknologi blockchain dapat mengurangi risiko pemalsuan data pendidikan, meningkatkan transparansi dalam penilaian akademik, serta memungkinkan otomatisasi proses administrasi melalui smart contracts. Studi menunjukkan keberhasilan pengembangan aplikasi berbasis blockchain untuk validasi sertifikat dan pengelolaan data akademik yang lebih transparan.  Selain itu, blockchain mampu menyediakan sistem pembayaran digital yang lebih efisien. Namun, tantangan terkait infrastruktur teknologi, biaya implementasi, dan pemahaman tentang blockchain masih menjadi hambatan utama dalam adopsinya di sektor pendidikan. Oleh karena itu, penting untuk mengembangkan sistem pendukung serta program pelatihan guna mempercepat adopsi blockchain dalam pendidikan, agar potensi penuh teknologi ini dapat terwujud
ETIKA DAN PRIVASI DALAM ERA KECERDASAN BUATAN DI RUMAH SAKIT : SYSTEMATIC LITERATURE REVIEW
Authors: Zhafran Zharif Demas , Reza Putra Prasetyo Muhammad , Andaru Abyan Muhammad , Lathif Mardi Suryanto Tri
Published: January 2025

Kemajuan teknologi kecerdasan buatan (AI) telah membawa perubahan signifikan dalam sektor kesehatan, khususnya di rumah sakit. AI memiliki potensi untuk meningkatkan kualitas pelayanan kesehatan melalui diagnosis yang lebih cepat dan akurat, serta optimalisasi pengambilan keputusan medis. Namun, penerapannya menghadapi sejumlah permasalahan terkait privasi data pasien dan etika, seperti risiko kebocoran data sensitif dan bias algoritmik yang dapat mempengaruhi keputusan medis. Penelitian ini bertujuan untuk menilai dampak penerapan AI terhadap etika dan privasi di rumah sakit. Metode yang digunakan adalah kajian literatur dengan pendekatan PRISMA, mencakup studi dari basis data seperti PubMed, Google Scholar, dan Claude.AI, dengan fokus pada artikel lima tahun terakhir (2019-2024). Hasil penelitian menunjukkan bahwa rumah sakit perlu menerapkan protokol keamanan data yang ketat, memastikan transparansi algoritma, serta melibatkan pasien untuk membangun kepercayaan publik. Dengan pendekatan yang bertanggung jawab, AI dapat dimanfaatkan untuk meningkatkan kualitas layanan kesehatan tanpa mengorbankan hak privasi dan aspek etika pasien.
ANALISIS BUKTI DIGITAL TWITTER WEB MENGGUNAKAN LIVE FORENSIC PADA KASUS CYBERBULLYING
Authors: Halimah Nur , Ami Fahmi
Published: January 2025

Perkembangan teknologi komputer yang semakin pesat tentunya memberikan berbagai dampak positif, namun perkembangan teknologi tentunya juga memiliki dampak negatif seperti tindak kejahatan pada dunia maya yang semakin meningkat. Cyberbullying merupakan salah satu jenis tindak kejahatan cyber yang hingga saat ini masih sering terjadi. Tindak kejahatan ini sering terjadi di platform media sosial Twitter, sehingga diperlukan penanganan yang lebih lanjut agar kasus kejahatan tersebut dapat diselesaikan dan pelaku dapat dimintai pertanggungjawaban atas perbuatannya. Maka dari itu penelitian ini dilakukan untuk mempermudah penyidik dalam mencari bukti tindakan cyberbullying yang nantinya akan dijadikan sebagai barang bukti digital. Dalam forensik digital, live forensic digunakan untuk mengumpulkan bukti digital dengan menerapkan metode NIST. Metode NIST SP 800-86 terdiri dari empat tahapan, yaitu collection, examination, analysis, dan reporting. Pada penelitian ini, proses live forensic dilalukan dengan menggunakan tools FTK Imager dan HxD Editor untuk mendapatkan barang bukti 100% yang berupa teks percakapan antara pelaku dan korban. Skenario kejahatan ini dirancang untuk mendapatkan bukti perundungan yang nantinya akan digunakan sebagai alat pendukung dalam pelaporan kepada pihak yang berwajib, sesuai dengan Pasal 27 Ayat (3) UU ITE
PERANCANGAN SISTEM INVENTORY MOTOR BERBASIS WEB UNTUK MANAJEMEN STOK TERDESENTRALISASI DAN OTORISASI KEUANGAN
Authors: Yuda Pratama Rangga , Galih Sulaksono Aditya
Published: January 2025

Perusahaan dengan banyak cabang membutuhkan sistem manajemen inventaris yang efisien untuk memastikan kelancaran operasional. PT. Armada TunasJaya menghadapi tantangan dalam mengelola stok secara real-time dan menerapkan otorisasi keuangan yang fleksibel. Penelitian ini bertujuan merancang sistem berbasis web untuk mendukung manajemen stok terdesentralisasi dan otoritas keuangan. Metode pengembangan menggunakan model waterfall. Hasil menunjukkan sistem ini mampu meningkatkan efisiensi pengeloaan stok dan memberikan laporan secara real-time kepada pusat tanpa menghambat fleksibilitas cabang. Penelitian ini memberikan kontribusi signifikan terhadap pengembanagn teknologi informasi di bidang manajemen inventaris
OPTIMALISASI MANAJEMEN PROSES BISNIS YOLAH AUTHENTIC FROZEN YOGURT MELALUI ANALISIS SWOT UNTUK MENINGKATKAN DAYA SAING DI ERA DIGITAL
Authors: Savina Savina , Antonius Alijoyo Franciskus , Shofiah Hilabi Shofa
Published: January 2025

Usaha Mikro Kecil dan Menengah (UMKM) di industri makanan sehat, seperti Yolah Authentic Frozen Yogurt menghadapi tantangan serius dalam mempertahankan daya saing di tengah disrupsi digital. Salah satu kendala utama adalah keterbatasan sumber daya, infrastruktur dan rendahnya literasi teknologi yang menghambat optimalisasi pemasaran digital. Akibatnya, manajemen proses bisnis Yolah menjadi kurang efektif dalam mendukung proses bisnis. Penelitian ini bertujuan merumuskan solusi strategis dan rekomendasi praktis untuk meningkatkan manajemen proses bisnis Yolah, dengan menekankan pentingnya pemasaran digital sebagai alat untuk menghadapi disrupsi dan memastikan keberlanjutan usaha di era transformasi teknologi. Metode yang digunakan adalah pendekatan SWOT dengan pengumpulan data deskriptif kualitatif melalui wawancara mendalam. Data primer diperoleh dari wawancara dengan pemangku kepentingan utama, sementara data sekunder dikumpulkan melalui studi literatur terkini. Metode ini dirancang untuk menganalisis faktor internal dan eksternal yang memengaruhi kinerja pemasaran digital Yolah. Hasil penelitian menunjukkan bahwa pemasaran digital Yolah belum dikelola secara optimal. Meskipun Yolah memiliki kualitas produk yang baik, pemanfaatan teknologi digital dalam strategi pemasaran masih terbatas. Penelitian ini merekomendasikan pengembangan strategi pemasaran digital yang lebih terarah serta peningkatan literasi teknologi digital untuk mendongkrak daya saing UMKM di era digital
PEMETAAN PENYEBARAN KASUS STUNTING DENGAN GEOGRAPHIC INFORMATION SYSTEM
Authors: Sulaeman Syams , Juardi Didi , Susilo Yuda Irawan Agung
Published: January 2025

Stunting adalah masalah kurang gizi kronis yang disebabkan oleh asupan gizi yang kurang dalama waktu yang cukup lama akibat pemberian makanan yang tidak sesuai dengan kebutuhan gizi. Stunting dapat terjadi mulai janin masih dalam kandungan dan baru Nampak saat anak berusia dua tahun. Dalam upaya menemukan daerah yang memiliki kasus penyakit stunting dapat menggunakan Geographic Information System (GIS). Pada penelitian ini data yang digunakan tahun 2020-2023 yang bersumber dari Dinas Kesehatan Kabupaten Karawang.Tujuan penelitian ini adalah pemetaan kasus stunting dari 30 kecamatan di Kabupaten Karawang.Metode yang digunakan dalam penelitian ini adalah dengan deskriptif kuantitatif untuk membantu proses penelitian dan juga menggunakan tools ArcGIS 10.8. Dari penelitian ini dihasilkan 6 kategori dengan interval kelas 264, dengan keterangan status pada setiap kategori nya mulai dari kategori 1 sangat rendah, kategori 2 rendah, kategori 3 sedang, kategori 4 siaga, kategori 5 tinggi, kategori 6 sangat tinggi. Didapatkan bahwa 16 kecamatan dengan kategori 1, 5 kecamatan dengan kategori 2, 1 kecamatan dengan kategori 3, 3 kecamatan dengan kategori 4, 2 kecamatan dengan kategori 6
RANCANG BANGUN APLIKASI SELULER YANG BERPUSAT PADA PENGGUNA UNTUK RESEP DAN BELANJA BAHAN MAKANAN
Authors: Purnomo Yunianto , Putro Endi , Sakti Lee Francka , Kastanya Lidia , Angellia Onggo Kallista , Noviana Lina
Published: January 2025

Memasak merupakan aktivitas penting yang tidak hanya memenuhi kebutuhan nutrisi tetapi juga meningkatkan kualitas hidup. Masyarakat modern sering menghadapi kesulitan dalam mencari dan membeli bahan masakan yang sesuai dengan resep secara manual, yang dapat mengurangi motivasi untuk mencoba resep baru. Meskipun aplikasi memasak berbasis teknologi semakin berkembang, mayoritas belum menyediakan fitur belanja bahan yang terintegrasi. Penelitian ini bertujuan merancang aplikasi seluler yang mengintegrasikan resep masakan dan belanja bahan berbasis Mobile Application Development Life Cycle (MADLC) untuk meningkatkan aksesibilitas resep dan kenyamanan pengguna dalam memperoleh bahan. Tahapan pengembangan mencakup: Identifikasi kebutuhan pengguna, Perancangan antarmuka awal dan struktur database, Pengembangan fitur aplikasi, Pengujian untuk memastikan fungsi fitur, Implementasi awal aplikasi. Hasil pengujian Black-box dan pengujian berbasis pengguna menunjukkan bahwa aplikasi berfungsi dengan baik sesuai dengan spesifikasi yang dirancang. Pengguna merasa puas dengan kemudahan pencarian resep, kelengkapan informasi resep, dan kelancaran proses checkout untuk belanja bahan. Meskipun demikian, beberapa saran untuk pengembangan lebih lanjut, seperti penambahan fitur personalisasi dan peningkatan antarmuka aplikasi, diusulkan untuk meningkatkan pengalaman pengguna. Aplikasi ini dapat meningkatkan efisiensi, kreativitas, dan motivasi pengguna dalam memasak, serta menjadi alat praktis yang mendukung gaya hidup