bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Partisipasi Anggaran dan Gaya Kepemimpinan Terhadap Kinerja Manajerial dengan Job Relevant Information sebagai Pemoderasi
Authors: Syukri Muhammad , Surasni Ni Ketut , Furkan Lalu M.
Published: March 2020

The study aims to reveal the effect of budgetary participation and leadership style on managerial performance as well as the influence of job relevant information in strengthening the influence of budgetary participation relationships and leadership style on managerial performance. Sources of data in the study using a questionnaire distributed to 43 West Lombok Regency OPD. The results showed budget participation and leadership style involved managerial performance and the original sample value showed positive budget participation and leadership style related to the direction of managerial performance, work related information did not support job relevant information did not support improvement of leadership style on managerial performance and sample value Original shows negative.

Keywords : Budgetary Participation; Leadership Style; Job Relevant Information Managerial Performance.
Pengaruh Manajemen Laba Pada Nilai Perusahaan Dengan Agresivitas Pajak Sebagai Variabel Intervening
Authors: Wahyuni Ni Wayan Intan Saskara , Budiasih I Gusti Ayu Nyoman
Published: March 2020

This study aims to analyze and determine the effect of earnings management on company value with tax aggressiveness as an intervening variable. The theoretical implications of this research to be able to support the application of agency theory and signaling theory by conducting research on a straightforward basis. The study was conducted on mining companies listed on the Indonesia Stock Exchange in 2012-2018. This study uses quantitative data types and secondary data sources with the number of observations obtained as many as 60 observations determined using the nonprobability sampling method with a purposive sampling technique as a sample selection method. Data analysis technique used in this research is path analysis with SPSS program. Based on the results of the path analysis in this study shows that earnings management has no effect on tax aggressiveness. Tax aggressiveness has a negative effect on company value. Earnings management has a negative effect on company value. Earnings management does not affect indirectly the value of the company through tax aggressiveness.

Keywords : Earnings Management; Tax Aggressiveness; Company Value.
Retomando a educação ambiental crítica a partir dos pressupostos de Paulo Freire e Enrique Dussel
Authors: Freitas André Luis Castro de , Freitas Luciane Albernaz de Araujo
Published: March 2020

O estudo tem como objetivo constituir aproximações entre o campo da educação ambiental crítica e os pressupostos trabalhados por Freire e Dussel. A partir de um estudo descritivo crítico, resultante de uma pesquisa de abordagem qualitativa, bibliográfica, tem-se como intenção elencar a relevância no campo das relações educativas as categorias: alteridade, diálogo e dialética. Reflete-se sobre a dicotomia existente entre uma educação ambiental a qual anuncia boas práticas individuais e aquela a qual denuncia a insustentabilidade. Na segunda parte, compreende-se sobre a necessidade de que se caminhe na direção da liberdade do Outro para que se alcance a própria. Após, encaminha-se uma discussão a qual trata o respeito à vida, pela valorização da identidade cultural dos seres humanos.
Letramento matemático: um processo construído pelo narrar e pelas linguagens
Authors: Luvison Cidinéia da Costa , Silva Luzia Batista de Oliveira
Published: March 2020

O presente artigo trata-se de um recorte de uma pesquisa de doutorado defendida no ano de 2017 e que investigou sobre o processo de letramento matemático a partir de narrativas para a apropriação da linguagem e de conceitos matemáticos. Para este texto o objetivo é trazer algumas discussões sobre o letramento em aulas de matemática (Kleiman) e o uso das linguagens enquanto parte do desenvolvimento conceitual pelo aluno (Bakhtin; Ricoeur; e Vigotski). Para isso, foram selecionadas algumas narrativas orais e escritas de alunos do 3º ano do Ensino Fundamental de uma escola pública municipal do interior de São Paulo. Os resultados evidenciaram que o letramento está aliado as práticas sociais, a partir da ação planejada na sala de aula, trazendo a possibilidade do aluno comunicar, ler, narrar e transformar-se.
O trabalho com gêneros textuais em um curso de Pedagogia: uma proposta de produção editorial para o letramento profissional
Authors: Feitoza Claudia de Jesus Abreu , Moretto Milena
Published: March 2020

Em nossas experiências como professoras do ensino superior, temos observado que são muitas as dificuldades de escrita de alunos ingressantes e, inclusive, concluintes nos cursos de Pedagogia. Diante disso, neste texto, temos como objetivo discutir acerca das contribuições de uma experiência prática de formação inicial, no que diz respeito à aprendizagem de leitura e escrita de gêneros textuais que, embora não pertençam à esfera acadêmica, serão objeto de ensino dos pedagogos em atuação nos diferentes segmentos de ensino e anos em que irão atuar. Fundamentando-nos na perspectiva enunciativo-discursiva e nas considerações dos Novos Estudos do Letramento, desenvolvemos um trabalho de produção editorial que, diante de nossas análises, contribuiu para o letramento profissional dos estudantes.
Electro polymerization for (N-Terminal tetrahydrophthalamic acid) for Anti-corrosion and Biological Activity Applications
Authors: Saleh Khulood A. , Ali Mayasa I.
Published: March 2020

The present work reports the electrochemical synthesis of poly N Terminal tetrahydrophthalamic acid on stainless steel 316 (S.S), which acts as a working electrode, using an electrochemical polymerization technique. Fourier Transform Infrared Spectroscopy (FT-IR), Atomic Force Microscope (AFM) and Scanning Electron Microscope (SEM) characterized the formed polymer film. Corrosion protection tests for coated and uncoated S.S with polymer film were studied in 0.2 M hydrochloric acid (HCl) solution by using electrochemical polarization technique. Kinetic and thermodynamic activation parameters (Ea, A, Î”H*, Î”S* and Î”G*) were calculated. The biological activity of the polymeric film was determined against Gram positive (Staphylococcus aureus; Staph.aure) and negative bacteria (Escherichia coli; E.coli).In addition, the polymer film was modified with nanomaterials(ZnOnnano and Graphene).
Synthesis and Antimicrobial Studies of New [Tetrakis (1, 2, 4-Triazole / 1, 3, 4-Oxadiazole / 1, 3, 4-Thiadiazole] [Bis-(Benzene-1, 3, 5-Triyl)] Dioxymethylene Compounds
Authors: Ayyash Ahmed Neamah
Published: March 2020

Synthesis of new heterocyclic compounds containing four five-membered rings together was the main goal of this work. The new derivatives of [tetrakis (1,2,4-triazole /1,3,4-thiadiazole /1,3,4-oxadiazole][bis-(benzene-1,3,5-triyl)] dioxymethylene A7-A18 were synthesized by the reaction of [bis-(dimethyl 5-yl-isophthalate)] dioxymethylene compound A1 which was previously prepared from the reaction of 1,2-dibromomethan and dimethyl 5-hydroxyisophthalate, then treated with hydrazine hydrate to yield the corresponding acid hydrazide A2. In the next step, compound A2 was refluxed with 4-substituted isothiocyanate to give substituted thiosemicarbazides A3-A6. The treatment of the latter compounds in basic medium of 2M of NaOH afforded 1,2,4-Triazole derivatives A7-A10. Whereas the reaction of the same compounds with concentrated sulfuric acid gave 1,3,4-thiadiazoles  A11-A14. Furthermore, the new derivatives of 1,3,4-oxadiazole A15-A18 were obtained by the reaction of thiosemicarbazides and tosyl chloride in presence of pyridine. (C. H. N.) elemental analysis, FT-IR, and 1HNMR techniques were used to characterize the chemical structure of some of the new synthesized compounds which also exhibited an important biological activity.
Entrepreneurship Education and Nascent Entrepreneurship: A Qualitative Study
Authors: Games Donard , Sari Dessy Kurnia , Darlis Venny
Published: March 2020

The objective of this research is to see whether entrepreneurship education and training really help nascent entrepreneurs particularly when they try to face the real business. Formal and non-formal entrepreneurship educations are commonly offered in Indonesia nowadays as entrepreneurship has become national campaign. Qualitative approach is used in this research. Multiple case studies methods are used to discover the relationship between entrepreneurship education and the success of nascent entrepreneurs in SMEs development. We asked young entrepreneurs, who were nascent entrepreneurs in West Sumatera-a province in Indonesia. We asked them about the effectiveness of entrepreneurship training and education in determining their success as entrepreneurs. We found that education has contributed positively in terms of motivation, but less benefit in technical ability and practical aspect in business world. These young entrepreneurs define their achievement now as “small win” which can lead them to the next level of success as entrepreneurs.
LEYES DE CAMBIO CLIMÁTICO E INFORMES VOLUNTARIOS DE CARBONO EN EL CONTEXTO EUROPEO
Authors: Mateo-Márquez Antonio Jesús , González-González José María , Zamora-Ramírez Constancio
Published: March 2020

La literatura previa ha prestado poca atención a cómo influye la regulación específica de cambio climático en los informes voluntarios de carbono de las empresas, habiendo sido escasamente considerado, especialmente, el contexto europeo. Así, la novedad de este trabajo radica en la incorporación y medición de regulaciones específicas de cambio climático en el análisis de los informes voluntarios de carbono en el caso de los países europeos. Esto es importante, dada la proliferación de leyes sobre cambio climático en la Unión Europea. Basándose en la perspectiva teórica del Nuevo Institucionalismo Sociológico (NIS), este trabajo analiza datos de 1.089 compañías europeas que fueron invitadas a participar en el cuestionario Carbon Disclosure Project (CDP) 2015. Los resultados revelan que la regulación de cambio climático afecta positivamente tanto a la participación de las empresas en el cuestionario CDP, como al nivel de transparencia. Este estudio proporciona nuevos conocimientos sobre cómo las empresas utilizan la divulgación voluntaria de carbono para adaptarse a las expectativas sociales generadas por la regulación obligatoria de cambio climático en su contexto institucional.
KESENIAN TARI DOLALAK SEBAGAI BRAND KABUPATEN PURWOREJO, JAWA TENGAH
Authors: Setyawan Agus Budi
Published: March 2020

Dolalak di Kabupaten Purworejo sebagai salah satu wujud dari seni tradisi kerakyatan, kehadirannya merupakan kelangsungan kehidupan kultural yang sudah berakar secara turun-temurun yang menjadi salah satu perwujudan budaya. Seiring perkembangannya, Dolalak dijadikan sebagai ikon kesenian untuk mendukung aktivitas branding pariwisata yang dilakukan oleh kabupaten Purworejo. Penelitian ini bertujuan untuk menjawab mengapa kabupaten Purworejo memilih Dolalak sebagai ikon keseniannya; upaya apa saja yang sudah dilakukan oleh kabupaten Purworejo dalam membangun brand Dolalak; serta bagaimana strategi pencitraan yang sudah dilakukan yang meliputi strategi visual dan strategi media. Penelitian ini menggunakan paradigma kualitatif dengan pendekatan etnografi, data penelitian didapatkan melalui wawancara dan observasi. Hasil penelitian mengungkap bahwa Dolalak dipilih sebagai ikon kesenian karena asli dari Purworejo, memiliki keunikan, eksis sampai saat ini, populer dan keberadaannya diterima oleh masyarakat Purworejo. Berbagai upaya telah dilakukan untuk membangun brand Dolalak, diantaranya dengan mementaskan Dolalak secara rutin dan mengirim Dolalak untuk mengikuti berbagai festival seni budaya di kabupaten/kota lain serta mengalihwahanakan Dolalak ke dalam berbagai media komunikasi visual. Melalui aktivitas branding yang dilakukan, Dolalak semakin dikenal oleh masyarakat, menguatkan positioning Kabupaten Purworejo, serta turut berperan dalam peningkatan kunjungan wisata di Purworejo.
Local and Regional Programmes of Environmental Protection as the Instrument of Implementation of Environmental Policy
Authors: Strus Dorota
Published: March 2020

The subject of the study is the analysis of programmes of environmental protection elaborated at the regional and local level. The paper indicates the conditions accompanying the shaping of programmes of environmental protection and the valid construction in the scope of their elaboration and implementation. The important issue to which attention was paid is the significance of programmes of environmental protection as a key element of the implementation of the national environmental policy.

Raksta mērķis ir analizēt vides aizsardzības programmas, kas izstrādātas reģionālā un vietējā līmenī. Rakstā tiek uzsvērti nosacījumi, kas jāievēro, veidojot vides aizsardzības programmas un derīgas konstrukcijas to izstrādei un ieviešanai. Svarīgs jautājums, kam pievērsta uzmanība, ir vides aizsardzības programmu nozīmīgums kā galvenais elements valsts vides politikas īstenošanā.
Mediācijas piemērošanas iespējas veselības aprūpes jomā
Authors: Palkova Karina
Published: March 2020

Rakstā aplūkota mediācijas procesa piemērošana strīdos starp pacientiem un ārstniecības personām veselības aprūpes jomā. Lai izvērtētu strīdu starp pacientiem un ārstniecības personām un gūtu ātrāku un kvalitatīvāku iespējamo risinājumu, nepieciešams izvērtēt mediācijas piemērošanu strīdos veselības aprūpes jomā. Pētījuma rezultāti ļauj secināt, ka tiesību normu saturs pieļauj mediācijas piemērošanu medicīnas tiesību jomā, taču, lai mediācijas process pilnvērtīgi darbotos, nepieciešams ievērot priekšnoteikumus, kas tiks pētīti darbā.

The aim of the article is to provide some insight into an opportunity to use mediation in healthcare disputes in Latvia. Mediation is the process or form of alternative dispute resolution. Mediation is not yet popular in Latvia but in Europe the process has gained strong background. The number of applications in healthcare cases before the court are growing. It shows that there are some problems in healthcare legal system that should be improved. The article highlights the practical side of the problem to use mediation in disputes between patients and medical persons, as well as relationships and communication problems between both parties. The results of the research show that legislation allows applying mediation in healthcare disputes. Nevertheless, in order to make mediation process more popular in that particular sphere, it is necessary to comply with several conditions.
Spin–Phonon Coupling and Dynamic Zero-Field Splitting Contributions to Spin Conversion Processes in Iron(II) Complexes
Authors: Higdon Nicholas , Barth Alexandra , Kozlowski Patryk , Hadt Ryan
Published: March 2020

Magnetization dynamics of transition metal complexes manifest in properties and phenomena of fundamental and applied interest (e.g., slow magnetic relaxation in single molecule magnets (SMMs), quantum coherence in quantum bits (qubits), and intersystem crossing (ISC) rates in photophysics). While spin–phonon coupling is recognized as an important determinant of these dynamics, additional fundamental studies are required to unravel the nature of the coupling and thus leverage it in molecular engineering approaches. To this end, we describe here a combined ligand field theory and multireference ab initio model to define spin–phonon coupling terms in S = 2 transition metal complexes and demonstrate how couplings originate from both the static and dynamic properties of ground and excited states. By extending concepts to spin conversion processes, ligand field dynamics manifest in the evolution of the excited state origins of zero-field splitting (ZFS) along specific normal mode potential energy surfaces. Dynamic ZFSs provide a powerful means to independently evaluate contributions from spin-allowed and/or -forbidden excited states to spin–phonon coupling terms. Furthermore, ratios between various intramolecular coupling terms for a given mode drive spin conversion processes in transition metal complexes and can be used to analyze mechanisms of ISC. Variations in geometric structure strongly influence the relative intramolecular linear spin–phonon coupling terms and will thus define the overall spin state dynamics. While of general importance for understanding magnetization dynamics, this study links the phenomenon of spin–phonon coupling across fields of single molecule magnetism, quantum materials/qubits, and transition metal photophysics.
Nanomechanical Properties and Failure Mechanisms of Two-Dimensional Metal-Organic Framework Nanosheets
Authors: Zeng Zhixin , Flyagina Irina , Tan Jin-Chong
Published: March 2020

Nanoscale mechanical properties measurement of porous nanosheets presents many challenges. Herein we show atomic force microscope (AFM) nanoindentation to probe the nanoscale mechanical properties of a 2‑D metal‑organic framework (MOF) nanosheet material, termed CuBDC [copper 1,4‑benzenedicarboxylate]. The sample thickness was ranging from ~10 nm (tens of monolayers) up to ~400 nm (stack of multilayers). In terms of its elastic‑plastic properties, the Young’s modulus (E ~ 22.9 GPa) and yield strength (𝜎Y ~ 448 MPa) have been determined in the through-thickness direction. Moreover, we have characterized the failure mechanisms of the CuBDC nanosheets, where three failure mechanisms have been identified: interfacial sliding, fracture of framework, and delamination of multilayered nanosheets. Threshold forces and corresponding indentation depths corresponding to the failure modes have been determined. To gain insights into the failure mechanisms, we employ finite-element models with cohesive elements to simulate the interfacial debonding of a stack of 2‑D nanosheets during the indentation process. The nanomechanical AFM methodology elucidated here will be pertinent to the study of other 2‑D hybrid nanosheets and van der Waals solids.
A distração da meninada nas ruas de São Paulo no início do século XX
Authors: Mimesse Prado Eliane
Published: March 2020

As crianças e jovens que viviam na cidade paulistana nos anos iniciais do século XX tiveram seus momentos para a diversão, normalmente com grupos de amigos. Identificaram-se  brincadeiras e jogos conhecidos entre esses sujeitos. A cidade de São Paulo crescia a cada dia, com a entrada de imigrantes das mais diversas etnias. As novas fábricas atraiam a mão de obra que estava ociosa no interior do estado. O aumento no fluxo de bondes para o transporte de passageiros e de carroças de serviços nas ruas cresceu, na mesma proporção que as fábricas. As ruas tornaram-se mais movimentadas e, consequentemente, mais perigosas, começaram a ameaçar e restringir a diversão da meninada. A fonte primária para este estudo foram as notícias de um periódico em circulação chamado O Estado de S. Paulo. As referências teóricas foram compostas por Cruz (2013) quando tratou da urbanização da cidade paulistana e de Pereira (2010) que focou no desenvolvimento fabril e urbano no início do século XX; Moura (2000) abordou a questão do trabalho infantil na urbe; e Autor (2018) por estudar os abandonados e órfãos na capital paulista; entre outros. Conclui-se que, apesar da expansão da cidade e do breve trânsito nas ruas, as crianças e jovens conseguiram divertir-se e encontrarem locais para sua recreação
Archaeology in the classroom: A perspective from Kiangan, Ifugao, Philippines | Arkiyoloji sa silid-aralan: Isang pananaw mula sa Kiangan, Ifugao
Authors: Dulnuan Jennifer Humiwat , Ledesma Charmaine P.
Published: March 2020

How can archaeology enhance public knowledge of local history in a community? This paper explored this question in an elementary-level social studies class in the town of Kiangan, Ifugao, Philippines, where archaeological excavations took place between 2012 and 2017. The authors present an example of the process of integrating archaeology in the classroom. As a form of public archaeology, “archaeology education” in this project utilized archaeological and Place-Based Learning concepts to develop archaeology modules that complemented classroom learning. This paper recounts the pilot project by providing details of the process of designing and developing the modules, the assessment, and the final product.Paano mapapahusay ng arkiyoloji ang pangkalahatang kaalaman ng lokal na kasaysayan sa isang pamayanan? Sinayasat ang tanong na ito sa isang pang-elementaryang antas ng Araling Panlipunan sa bayan ng Kiangan, Ifugao, kung saan naganap ang isang arkeolojikal na paghuhukay (taon 2012-2017). Ipapakita ng mga may-akda ang isang halimbawa ng proseso sa paglakip ng arkiyoloji sa pagtuturo ng Araling Panlipunan. Bilang isang uri ng “public archaeology” o pangkalahatang arkiyoloji, ang “archaeology education” na proyektong ito ay gumamit ng mga konseptong arkeolojikal at “Place-based Learning” para mabuo ang mga arkeolojikal na modyul na makakatulong sa pagturo ng Araling Panlipunan. Isasalaysay din ng papel ang proyekto sa pamamagitan ng pagbibigay ng detalyeng proseso ng pagdidisenyo at pagkakabuo ng mga arkiyolojikal na modyul, ang mga obserbasyon, at ang pangwakas na resulta ng proyekto.
UJI DAYA HAMBAT ANTIBAKTERI AIR PERASAN DAGING BUAH NANAS (ANANAS COMOSUS (L) MERR VAR. QUEEN) TERHADAP BAKTERI PROPIONIBACTERIUM ACNES
Authors: Sarwendah Sarwendah , Yusliana Yusliana , G Laia Heronimus Candra , Daely Pieter Julius , Chiuman Linda
Published: March 2020

Abstrak: Buah nanas (Ananas comosus (L) Merr) merupakan salah satu jenis buah-buahan tropis yang banyak diminati masyarakat. Buah nanas biasa dingunakan masyarakat sebagai antibakteri, antiinflamasi, antikoagulan, dan antikanker. Tujuan dari penelitian ini untuk mengetahui uji daya hambat anti bakteri air perasan daging buah nanas (Ananas comosus (L) Merr Var.ÃÂ  Queen) terhadap bakteri Propionibacterium acnes. Penelitian ini merupakan penelitian eksperimental laboratorium dengan menggunakan metode difusi kertas cakram. Hasil dari penelitian menunjukkan bahwa air perasan daging buah nanas (Ananas comosus (L) Merr Var. Queen) pada konsentrasi 25%, 50%, 75%, 100% memiliki efektivitas sedang sebagai antibakteri dalam menghambat pertumbuhan bakteri Propionibacterium acnes, pada kontrol positif yang menggunakan klindamisin dengan rata-rata diameter zona hambat sebesar 25,8 mm memiliki pengaruh antibakteri yang sangat kuat dan untuk kontrol negatif dengan menggunakan aquades tidak menunjukkan zona hambat 0 mm pada bakteri Propionibacterium acnes.Kata kunci: Buah nanas, propionibacterium acnes, daya hambat antibakteri.Abstract: Pineapple (Ananas comosus (L) Merr) is one of the most popular fruit among people, Pineapple is used as antibacterial, anti-inlfammatory, anticoagulant and anticancer. The purpose of this study is to determine the antibacterial inhibitory test of pineapple juice (Ananas comosus (L) Merr Var. Queen) against Propionibacterium acnes. This research is a laboratory experimental using paper disc diffisuion method. The results of this study indicate that pineapple juice at concentration of 25%, 50%, 75%, 100% it has a moderately antibacterial effectiveness in inhibit the growth of Propionibacterium acnes, positive control using clindamycin with an average inhibition zone diameter of 25.8 mm has a very strong antibacterial effect and for negative control using aquades does not show 0 mm inhibition zone in Propionibacterium acnes bacteria.Keywords: Pineapple fruit, propionibacterium acnes, antibacterial inhibition.
Perbedaan Keterampilan Proses Sains Biologi Siswa Sekolah Menengah Atas Berdasarkan Tingkat Akreditas Sekolah
Authors: Safahi Luthpi , Akbar Budhi , Selvianah Anah , Astuti Yuni , Anugrah Devi
Published: March 2020

Penelitian ini bertujuan untuk mengetahui perbedaan keterampilan proses sains (KPS) Biologi siswa sekolah menengah atas akreditasi A dengan siswa sekolah menengah atas akreditasi B. Metode yang digunakan adalah deskriptif kausal kompratif. Populasi penelitian ini adalah siswa kelas XI SMA Swasta di Jakarta Barat Wilayah 1 Kecamatan Cengkareng tahun ajaran 2015/2016 yang berjumlah ±1.680 siswa. Pengambilan sampel dengan menggunakan teknik Cluster Random Sampling dan terpilih empat sekolah SMA Swasta dua Sekolah Akreditasi A (40 orang)  dan dua Sekolah Akreditasi B (40 orang). Penelitian dilakukan pada bulan Januari – Juni 2016. Instrumen penelitian  menggunakan tes objektif KPS yang terdiri dari 34 soal. Data penelitian dianalisis menggunakan Uji-t. Hasilnya menunjukkan thit (4,60) > ttabel (0,975) (1,99), Hipotesis ditolak, sehingga ada perbedaan keterampilan proses sains Biologi siswa sekolah menengah atas akreditasi A dengan siswa sekolah menengah atas akreditasi B.
A state model of negative urgency: Do momentary reports of emotional impulsivity reflect global self-report?
Authors: Feil Madison , Halvorson Max Andrew , Lengua Liliana , King Kevin Michael
Published: March 2020

In a sample of young adults (N = 222) assessed 3 times per day for 10 days, we tested whether negative emotions were associated with multiple facets of impulsivity at the state-level, and whether those associations were moderated by global self-report of negative urgency. Our findings suggest a robust within-person association between negative affect and acting on impulse. However, global self-report of negative urgency did not moderate any emotion-impulsivity association we tested.
Combining local and global evolutionary trajectories of brain-behavior equilibrium through game theory
Authors: Di Plinio Simone , Ebisch Sjoerd
Published: March 2020

The study of the evolution of brain-behavior relationships concerns understanding the causes and repercussions of cross- and within-species variability. Understanding such variability is a main objective of evolutionary and cognitive neuroscience, and it may help explaining the appearance of psychopathological phenotypes. Although the brain evolution is related to the progressive action of selection and adaptation through multiple paths (e.g., mosaic vs. concerted evolution, metabolic vs. structural and functional constraints), a coherent, integrative framework is needed to combine evolutionary paths and neuroscientific evidence. Here, we review the literature on evolutionary pressures focusing on structural-functional changes and developmental constraints. Taking advantage of progresses in neuroimaging and cognitive neuroscience, we propose a twofold model of brain evolution. Within this model, global and local trajectories imply rearrangements of neural subunits and subsystems as well as of behavioral repertoires of a species, respectively. We incorporate these two processes in a game in which the global trajectory shapes the structural-functional neural substrates (i.e., players), while the local trajectory shapes the behavioral repertoires (i.e., stochastic payoffs).
Life Satisfaction Trajectories during Adolescence and the Transition to Young Adulthood: Findings from a Longitudinal Study of Mexican-origin Youth
Authors: Willroth Emily C , Atherton Olivia E. , Robins Richard
Published: March 2020

Despite the importance of life satisfaction for health and well-being, there is a paucity of longitudinal studies tracking changes in life satisfaction in ethnic minority youth. Using a sample of 674 Mexican-origin youth, the present research examined life satisfaction trajectories from middle (age 14) to late adolescence (age 17) and from late adolescence to young adulthood (age 21). On average, life satisfaction did not change significantly from age 14 to 17, and then decreased from age 17 to 21 (d = .30), perhaps reflecting difficulties transitioning into adult roles. Drawing on ecological systems theory, we examined both proximal (i.e., family) and distal (i.e., social-contextual) environmental factors (measured via self- and parent-reports) that may account for between-person variation in life satisfaction trajectories. Youth with more positive family environments in middle adolescence (age 14) had higher mean life satisfaction from middle adolescence to young adulthood (age 21). In contrast, youth with more negative family environments and who experienced greater economic hardship and more ethnic discrimination in middle adolescence (age 14) had lower life satisfaction during this period. Many of these factors also predicted change in life satisfaction from middle (age 14) to late adolescence (age 17), but not from late adolescence to young adulthood (age 21). This research extends the current understanding of life satisfaction during a critical developmental period in an understudied population.
Kritik Sosial dalam Film Dokumenter Youtube “Najwa Shihab” (Analisis Semiotika Rolan Barthes)
Authors: Asriadi Asriadi
Published: March 2020

Penelitian ini membahas Kritik Sosial dalam sebuah Film Pendek karya Dr. Tompi yang di apload dalam akun youtube Najwa Shihab berjudul dengan Model Analisis Semiotika Roland Barthes . Hasil penelitian menunjukkan bahwa, tidak semua orang mewah makan ditempat yang mewah pula karena banyak di warung biasa bercampuan orang yang mewah dan sederhana (Tidak ada kelas). Juga menunjukkan bahwa ekspresi wajah seseorang adalah suara, memiliki dan menggambarkan makna ataupun pesan yang disampaikan dapat begitu jelas dan mudah di artikan.
Crowd Engineering – Produktentwicklung in der Community
Authors: Hertwig Michael , Barwasser Adrian , Lentes Joachim , Adam Frauke , Kalkuhl Johannes , Siee Maik
Published: March 2020

Kurzfassung

Fachkräftemangel, immer kürzere Produktlebenszyklen und der zunehmende Bedarf an kundenindividuellen Produkten führen zu steigenden Herausforderungen für Entwicklungsabteilungen produzierender Unternehmen. Die Einbindung von externen Experten aus einer Community in firmeninterne Produktentwicklungsprozesse ist ein erfolgversprechender Ansatz für die schnellere, kostengünstigere und bedarfsangepasste Entwicklung von Produkten. Mit Crowd Engineering wird die Einbindung einer Community in eine Produktentwicklung realisiert. Dieser Beitrag soll einen Einblick in den aktuellen Forschungsstand des Crowd Engineerings geben und den Nutzen für Unternehmen aufzeigen.
Handlungsmuster der Feuerwehr für das Störungsmanagement?
Authors: Gronau Norbert
Published: March 2020

Kurzfassung

Einsatzorganisationen, wie z. B. Feuerwehr oder Technisches Hilfswerk, müssen sehr schnell auf teilweise unbekannte Lagen reagieren und angemessene Hilfeleistung erbringen. Können Handlungsweisen und vorbereitende Maßnahmen dieser Organisationen auf die Störungsbeseitigung in Produktionssystemen übertragen werden? Ein Experiment in einem Cyber-Physischen Produktionssystem geht dieser Frage nach. Es zeigt sich, dass durch die Anwendung geeigneter Handlungsmuster sowohl die Dauer von Störungen als auch die Zeit für die Behebung verkürzt werden können.
Complicated Abdominal Seat Belt Injuries in Children
Authors: Sweed Yechiel , Yulevich Alon , Ciceu Gabriela , Singer-Jordan Jonathan , Apel-Sarid Liat , Loberant Norman , Arzumanov Tatyana , Sweed Yechiel , Hoffmann Yoav , Grozovsky Yuri
Published: March 2020

Background: The proper use of security accessories in cars has resulted in the reduction of morbidity and
mortality both in adults and children. Improper use of abdominal seat belt is associated in some cases with
severe abdominal injuries.
Objectives: Investigation of the treatment outcomes of children who suffered complicated abdominal seat
belt injuries between 1998 and 2013.
Methods: We present five cases of children aged 6-14 years, who suffered complicated abdominal injuries
due to improper use of the seat belt. Abdominal injuries included injuries to the liver, spleen, small bowel
(duodenum, jejunum, and ileum), colon and aorta, mesenterial bleeding, retroperitoneal bleeding, bowel
obstruction and pelvic fractures.
Results: Three children were operated on within a few hours of admission due to peritoneal irritation,
hemodynamic instability after fluid resuscitation, bowel injuries including perforation and bowel ischemia.
Two children who were hemodynamically stable, were operated on after few days. One of them had a
diagnosis of aortic injury and the other, bowel obstruction. The first child was treated in two stages: i. repair
of duodenal rupture, and ii. repair of the aortic injury by using interposition Gore-Tex graft. For the child
with bowel obstruction, segmental resection and primary anastomosis were performed. The operation and
postoperative periods for all children were uneventful, and all five children are healthy today.
Conclusion: 1) The abdominal seat belt should always be used in conjunction with the chest seat belt. 2)
An abdominal seat belt sign should always raise the possibility of complicated abdominal injuries. 3)
Gastrointestinal tract injuries are common in this setting. 4) Aortic injury is rare; however, it can easily be
missed initially. 5) Abdominal aortic trauma is associated with duodenal injuries in almost all cases.
Laparoscopic Central Gastrectomy for a Gastric Schwannoma: Case Report
Authors: Coturel Adelina E. , Coturel Adelina E. , M. Quesada Bernabé
Published: March 2020

Introduction: Schwannomas are tumors originating from any peripheral nerve that rarely arise in the
stomach.
Presentation of Case: A 77-year-old woman with nonspecific epigastric pain. EGD reveals a submucosal
bulge on the anterior wall of the gastric body. EUS showed a heterogeneous mass compatible with GIST.
We performed a laparoscopic central gastrectomy because a wedge resection wasn’t possible for the tumor
localization. Biopsy reveals it was a Schwannoma.
Discussion: Gastric Schwannomas are atypical mesenchymal gastric tumors that usually have non-specific
symptoms. Preoperative workup is made by EGD, EUS and CT but, commonly those methods couldn’t do
the differential diagnosis with GIST. Surgery is the treatment. Because it is not necessary to perform a
lymphadenectomy, the type of gastrectomy could be choosing within total, distal, wedge or atypical
resection, depending tumor size and location. There are not publications about central gastrectomy for GS.
Therefore, we decided to present this patient with a CG for GS, that showed good outcomes.
Conclusion: Central gastrectomy is an available option for Gastric Schwannomas when lateral or wedge
resection couldn’t be performed.
INSTITUTIONAL ECOSYSTEM AS A NEW PARADIGM OF NATURE MANAGEMENT DEVELOPMENT
Authors: RUBEL O. , AGHAYEV А. , KALED A ASALAM MOFTAH А. , ZHIKHAREVA A.A. , REZNICHENKO N.
Published: March 2020

Topicality. The non-institutional methodology of environmental management based on the formation of the “institutional ecosystem” has been considered and scientifically substantiated. The scientific categories that provide its methodological integrity are substantiated: “institutional dominants”, “replicates”, “institutional players”, decomposition of these concepts within the framework of modern economic-ecological and neo-institutional theory, its connection in the context of the formation the national institutional model of eco-management. A number of institutional innovations (replicates) have also been proposed, in particular the requirements for updating Annex XXX to the EU - UA Association Agreement in the context of the development of the national eco-management system.Aim and tasks. The aim of the article is to discuss the challenge to institutional development for institutional ecosystem as a new paradigm of nature management development.Research results. Institutional ecosystem - a dynamic, balanced, sustainable, self-replicating, regulated system that is "comfortable" for the entities of institutional relationships that transact with each other, is also a source of institutional ecosystem formation (role of the entity), involved in its formation , development, regulation (through the formation of institutional discourse), consumption (through the use of part of the institutional environment under its influence) and acting on principles: Institutional prediction based on the transformation of institutional dominance; -Replication (timely exit from the "comfort zone" for institutional transformations and system fertility at different hierarchical levels; Incubation - ensuring the completeness of the institutional cycle. There is an institutional ecosystem equilibrium balance between institutional rules (dominant), conditions (subdominants). However, this situation is short-lived: In the current context, institutional dominance is changing rapidly. And the institutional ecosystem has to “adjust” internal institutional conditions (subdominants) in order to obtain a state of equilibrium (institutional homeostasis).Conclusion. 1. The ecosystem, as a scientific category used in economics, is primarily characterized by internal dynamics and development under the influence of internal and external factors. 2. The ecosystem is seen as a network consisting of elements, some of which are the largest and define ecosystem health; it is defined by the relevant dominant. 3. Cooperative and mutual aid processes play an important role in the functioning of ecosystems, regardless of the status and capabilities of their participants. This approach is completely in line with the basic tenet of the non-institutional economy on the support and role of "weak links".
The Functional Tests after ACL Reconstruction with and without Meniscal Repair
Authors: Janewanitsataporn Sineenad
Published: March 2020

Objective: This study aims to compare the functional tests after anterior cruciate ligament reconstruction (ACLR) with and without meniscal repair after the rehabilitation program and before returning to sports. Material and Methods: Patients who underwent ACLR using hamstring tendon autograft during 2016-2017 were invited to participate in this study and divided into 2 groups including with and without meniscal repairs according to the surgical reports. A group of ACLR with meniscal repair required the conservative anterior cruciate ligament (ACL) rehabilitation program because the non-weight-bearing approach should be applied during the first 6 weeks. These patients were followed up clinically until the rehabilitation program finished. The functional tests were applied with the 4 single-leg hop tests, as reported in the limb symmetry index (LSI). Results: Forty-three patients were enrolled in the program. These patients were divided into 2 groups: ACLR with meniscal repair (n=20) and ACLR without meniscal repair (n=23). It was found that there was no statistically significant difference between the two groups with respect to duration for completing the rehabilitation program (p-value=0.38). Also, there was no statistically significant difference between the two groups with respect to the LSI of all 4 singleleg hop tests of duration for completing the rehabilitation program. Conclusion: The conservative ACL rehabilitation program after meniscal repair surgery did not affect the function tests in terms of duration for completing the rehabilitation program before return to sports (RTS).
Ứng xử ngang của gối cách chấn đàn hồi cốt sợi không liên kết hình khối hộp chịu chuyển vị lớn
Authors: Việt Vũ Quang , Thuyết Ngô Văn
Published: March 2020

Gối cách chấn đàn hồi cốt sợi không liên kết (gọi tắt là gối U-FREI) là một loại gối cách chấn tương đối mới đang được phát triển trên thế giới. Các nghiên cứu về gối U-FREI ở Việt Nam mới chỉ xem xét gối U-FREI chịu chuyển vị ngang với giá trị nhỏ (nhỏ hơn 1,0tr, trong đó tr là tổng chiều dày các lớp cao su trong gối U-FREI). Trong nghiên cứu này, ứng xử ngang của gối U-FREI hình khối hộp chịu đồng thời tải trọng thẳng đứng có giá trị không đổi và chuyển vị ngang vòng lặp dạng hàm điều hòa có độ lớn tăng dần đến giá trị 2,0trđược khảo sát bằng phương pháp phân tích mô hình số. Nghiên cứu chỉ ra rằng tại các chuyển vị nhỏ, độ cứng ngang của gối U-FREI giảm xuống do gối cách chấn có biến dạng cuộn, nhưng ở các chuyển vị lớn, độ cứng ngang của gối U-FREI tăng lên.

Từ khóa:

gối cách chấn; gối cách chấn đàn hồi cốt sợi không liên kết; biến dạng cuộn; ứng xử ngang; chuyển vị ngang lớn.
EVALUASI PENGGUNAAN OBAT PADA PASIEN OSTEOARTRITIS DI INSTALASI RAWAT JALAN RSUD DR. M. ASHARI PEMALANG PERIODE MARET-APRIL 2018
Authors: S Fithri Zahara , A Ebta Narasukma , N.S.H Maria Caecilia
Published: March 2020

ABSTRACT

Osteoarthritis (OA) is a degenerative joint illness characterized by cartilage destruction and

often found on older people. The drugs commonly used to treat OA symptoms is paracetamol,

nonsteroidal anti-inflammatory drugs (NSAIDs), food supplements such as glucosamine and

chondroitin. The purposes of these studies are identifying the OA patient's characteristics

(including gender and age), drug use evaluation based on the right patient, indication, and dose, as

well as the potency of drug interactions on OA patients. This research is non-experimental

research with a non-analytical descriptive design. The data was collected retrospectively with a

purposive sampling method from outpatients OA medical records in RSUD Dr. M. Ashari

Pemalang (March to April 2018 period). The results of this study indicate that patients have

suffered OA for 1-2 years (40%), generally women (72.94%) with an age range of 46-55 years

(39%). Most patients have an elementary school educational background (41%), and 43.53% of

them are overweight (BMI 25.00-29.99). All medicines prescribed for OA patient therapy have

been the right indication and patient. As many as 80.95% of the prescribed medicines had the right

dose, and 19.05% of prescription drugs case categorized as underdosing. Drug interactions

potency occurs in 30.58% of patients, with 29 cases.

Keywords: Osteoarthritis, drugs use evaluation, outpatient
PKM Ekonomi Produktif Melalui Technopreneurhip Bagi Guru di SMK Bisnis Dan Teknologi
Authors: Haryono Sugeng , Ariwibowo Prasetio , Djuhartono Tjipto
Published: March 2020

Tujuan kegiatan ini akan menambah wawasan Pendidikan Karakter Pribadi, Kewirausahaan (Technopreneurship), Menemukan Peluang Usaha, Manajemen usaha, Peningkatan keterampilan, berupa pelatihan pembuatan produk seperti kuliner, kerajinan tangan, Musik, Fashion, Desain Komunikasi Visual, Aplikasi dan Game Developer, dan keahlian lainnya bagi segenap civitas akademik khususnya guru baik secara teori maupun aplikasi/praktik secara nyata yang akan dilakukan oleh para guru sendiri maupun peserta didik nya sehingga diharapkan para guru dapat menambah penghasilan dan membuka lapangan kerja bagi diri sendiri maupun orang lain. Khalayak sasaran kegiatan yang strategis dalam kegiatan ini adalah para peserta didik dan segenap civitas akademik lainnya dalam naungan Yayasan SMKS Bisnis dan Teknologi Bekasi. Jumlah peserta pelatihan sebanyak 30-50 orang yang terdiri dari segenap civitas akademik (Guru atau karyawan sekolah) baik yang berjenis kelamin pria dan wanita yang telah ditetapkan oleh pihak pengurus Yayasan SMKS Bisnis dan Teknologi Bekasi. Selama proses pelatihan, tim pelaksana kegiatan pengabdian melakukan pemantauan kepada peserta pelatihan sekaligus melakukan wawancara terhadap materi, metode dan instruktur dalam kegiatan ini. Secara umum, peserta abdimas (guru) mengatakan pelatihan ini sangat baik dan materi yang diberikan merupakan materi yang sangat dibutuhkan dalam kegiatan berwirausaha berbasis technopreneur sedangkan instrukturnya sangat berkompeten.
Sinema-Konseling untuk Meningkatkan Ketahanan Psikologis Siswa Sekolah Menengah Kejuruan pada Era Digital
Authors: Mulawarman Mulawarman , Hariyadi Sigit , Antika Eni Rindi , Soputan Shania Dea Menany
Published: March 2020

Berbagai tekanan dalam era digital mengharuskan siswa memiliki ketahanan psikologis. Tujuan kegiatan pengabdian kepada masyarakat ini adalah untuk mengembangkan keterampilan konselor/guru BK dalam memberikan layanan kepada siswa sesuai dengan tuntutan perkembangan zaman. Strategi sinema-konseling dilatihkan kepada dua puluh konselor/guru BK Sekolah Menengah Kejuruan di Kabupaten Blora. Pelatihan ini dilaksanakan selama tiga hari yang setara dengan tiga puluh dua jam pelatihan, yaitu pada tanggal 1 sampai 3 Agustus 2019. Instrumen sinema konseling digunakan untuk mengukur keterampilan konselor/guru BK dalam mengaplikasikan strategi sinema-konseling. Hasil pelatihan menunjukkan rata-rata keterampilan konselor/guru BK dalam megaplikasikan strategi sinema-konseling mengalami peningkatan. Lebih lanjut konselor/guru BK perlu mempertajam keterampilan dalam mengembangkan pertanyaan reflektif dalam menerapkan strategi sinema-konseling di sekolah.
Sex Differences in the Phosphoproteomic Profiles of APP/PS1 Mice after Chronic Unpredictable Mild Stress
Authors: Dominguez Sky , Rodriguez Guadalupe , Fazelinia Hossein , Ding Hua , Spruce Lynn , Seeholzer Steven H. , Dong Hongxin
Published: March 2020

Approximately two-thirds of those suffering with Alzheimer’s disease (AD) are women, however, the biological mechanisms underlying this sex divergence of AD prevalence remain unknown. Previous research has shown sex-specific biochemical differences that bias female mice toward pro-AD signaling on the phosphoproteomic level via corticotropin releasing factor (CRF) receptor 1 activation after CRF overexpression. Here we aimed to determine if chronic stress would induce a similar response in AD mouse models. We stressed 4-month-old APP/PS1 mice using a chronic unpredictable mild stress (CUMS) paradigm for up to 1 month. Following CUMS and behavioral assessments, we quantified whole protein and phosphoprotein levels in the cortex of stressed and non-stressed APP/PS1 mice using mass spectrometry-based proteomics. While there were no statistically significant differences at the total protein and peptide abundance levels, we found 909 and 841 statistically significant phosphopeptides between stressed and unstressed females and males, respectively, using a false discovery rate of 5%. Of these significant phosphopeptides, only 301 were the same in males and females. These results indicate that while both males and females undergo protein phosphorylation changes following stress, the peptides that are phosphorylated differ between sexes. We then used Metacore analysis to determine which biological pathways were affected. We found that several pathways were changed differently between male and female mice including NMDA receptor trafficking, cytoskeleton organization, and tau pathology. The differing biological pathways affected between males and females in response to chronic stress may help us to better understand why women are at a higher risk of AD.
Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage
Authors: Cicognola Claudia , Satir Tugce Munise , Brinkmalm Gunnar , Matečko-Burmann Irena , Agholme Lotta , Bergström Petra , Becker Bruno , Zetterberg Henrik , Blennow Kaj , Höglund Kina
Published: March 2020

Background:

Tau aggregation in neurons and glial cells characterizes tauopathies as Alzheimer’s disease (AD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Tau proteolysis has been proposed as a trigger for tau aggregation and tau fragments have been observed in brain and cerebrospinal fluid (CSF). Our group identified a major tau cleavage at amino acid (aa) 224 in CSF; N-terminal tau fragments ending at aa 224 (N-224) were significantly increased in AD and lacked correlation to total tau (t-tau) and phosphorylated tau (p-tau) in PSP and CBD.

Objective:

Previous studies have shown cleavage from calpain proteases at sites adjacent to aa 224. Our aim was to investigate if calpain-1 or -2 could be responsible for cleavage at aa 224.

Methods:

Proteolytic activity of calpain-1, calpain-2, and brain protein extract was assessed on a custom tau peptide (aa 220–228), engineered with fluorescence resonance energy transfer (FRET) technology. Findings were confirmed with in-gel trypsination and mass spectrometry (MS) analysis of brain-derived bands with proteolytic activity on the FRET substrate. Finally, knock-down of the calpain-2 catalytic subunit gene ( CAPN2) was performed in a neuroblastoma cell line (SH-SY5Y).

Results:

Calpain-2 and brain protein extract, but not calpain-1, showed proteolytic activity on the FRET substrate. MS analysis of active gel bands revealed presence of calpain-2 subunits, but not calpain-1. Calpain-2 depletion and chemical inhibition suppressed proteolysis of the FRET substrate. CAPN2 knock-down caused a 76.4% reduction of N-224 tau in the cell-conditioned media.

Conclusions:

Further investigation of the calpain-2 pathway in the pathogenesis of tauopathies is encouraged.