bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables 1-5 from Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010
Authors: Ertl Hildegund C.J. , Zaia John , Rosenberg Steven A. , June Carl H. , Dotti Gianpietro , Kahn Jeffrey , Cooper Laurence J.N. , Corrigan-Curay Jacqueline , Strome Scott E.
Published: March 2023

Supplementary Tables 1-5 from Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010
Supplementary Methods and Materials from Prohibitin Attenuates Colitis-Associated Tumorigenesis in Mice by Modulating p53 and STAT3 Apoptotic Responses
Authors: Kathiria Arwa S. , Neumann William L. , Rhees Jennifer , Hotchkiss Erin , Cheng Yulan , Genta Robert M. , Meltzer Stephen J. , Souza Rhonda F. , Theiss Arianne L.
Published: March 2023

PDF file - 70K
Supplementary Figures 1-5, Tables 1-2 from Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells
Authors: Zhou Yunfei , Tozzi Federico , Chen Jinyu , Fan Fan , Xia Ling , Wang Jinrong , Gao Guang , Zhang Aijun , Xia Xuefeng , Brasher Heather , Widger William , Ellis Lee M. , Weihua Zhang
Published: March 2023

PDF file - 113K
Supplementary Movie 4 from In Vivo Imaging of Drug-Induced Mitochondrial Outer Membrane Permeabilization at Single-Cell Resolution
Authors: Earley Sarah , Vinegoni Claudio , Dunham Joshua , Gorbatov Rostic , Feruglio Paolo Fumene , Weissleder Ralph
Published: March 2023

AVI file, 353KB, Time lapse image sequence of PANC-1 pancreatic cancer cells treated with TRAIL, showing the fluorescent IMS-RP MOMP reporter. The cell with the asterisk undergoes MOMP during this image sequence. (The asterisk is offset because the cell moves during the sequence.)
Supplementary Figure 2 from CXCR6 Upregulation Contributes to a Proinflammatory Tumor Microenvironment That Drives Metastasis and Poor Patient Outcomes in Hepatocellular Carcinoma
Authors: Gao Qiang , Zhao Ying-Jun , Wang Xiao-Ying , Qiu Shuang-Jian , Shi Ying-Hong , Sun Jian , Yi Yong , Shi Jie-Yi , Shi Guo-Ming , Ding Zhen-Bin , Xiao Yong-Sheng , Zhao Zhong-Hua , Zhou Jian , He Xiang-Huo , Fan Jia
Published: March 2023

PDF file - 656K, CXCL16 expression in HCC and its relationship with clinical outcome
Supplementary Movie 2 from In Vivo Imaging of Drug-Induced Mitochondrial Outer Membrane Permeabilization at Single-Cell Resolution
Authors: Earley Sarah , Vinegoni Claudio , Dunham Joshua , Gorbatov Rostic , Feruglio Paolo Fumene , Weissleder Ralph
Published: March 2023

AVI file, 169KB, Time lapse image sequence of MDA-MB-231 breast cancer cells treated with ABT-263, showing the fluorescent IMS-RP MOMP reporter. The cell with the asterisk undergoes MOMP during this image sequence.
Supplementary Figure 7 from MLK3 Regulates Paxillin Phosphorylation in Chemokine-Mediated Breast Cancer Cell Migration and Invasion to Drive Metastasis
Authors: Chen Jian , Gallo Kathleen A.
Published: March 2023

PDF file - 38K, S178 phosphorylation of paxillin in human mammary epithelial and breast cancer cell lines
Supplementary Figure 6 from Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response
Authors: Mittendorf Elizabeth A. , Alatrash Gheath , Qiao Na , Wu Yun , Sukhumalchandra Pariya , St. John Lisa S. , Philips Anne V. , Xiao Haile , Zhang Mao , Ruisaard Kathryn , Clise-Dwyer Karen , Lu Sijie , Molldrem Jeffrey J.
Published: March 2023

PDF file - 82K, Results showing the ability of neutrophil elastase to cleave recombinant cyclin E
Supplementary Figure 3 from Global Quantitative Phosphoproteome Analysis of Human Tumor Xenografts Treated with a CD44 Antagonist
Authors: Weigand Stefan , Herting Frank , Maisel Daniela , Nopora Adam , Voss Edgar , Schaab Christoph , Klammer Martin , Tebbe Andreas
Published: March 2023

PDF file - 336K, No modulation of signaling in PL45 xenografts after RG7356 treatment
Supplementary Table 3, Figure 3 from An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis
Authors: Huang Xiumei , Dong Ying , Bey Erik A. , Kilgore Jessica A. , Bair Joseph S. , Li Long-Shan , Patel Malina , Parkinson Elizabeth I. , Wang Yiguang , Williams Noelle S. , Gao Jinming , Hergenrother Paul J. , Boothman David A.
Published: March 2023

PDF file - 668K, LD50 values for DNQ versus �-lap in various cancer cell types. Supplemental Figure 3. NQO1-dependent oxygen consumption rates (OCRs) in NSCLC cells after various doses of DNQ.
Supplementary Table 4 from Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
Authors: Lee Sangjun , Stewart Sheila , Nagtegaal Iris , Luo Jingqin , Wu Yun , Colditz Graham , Medina Dan , Allred D. Craig
Published: March 2023

PDF file - 58K, Growth and Progression of MIND Xenografts of DCIS.COM, hDCIS.01 and SUM225 transduced with shRNAi against candidate DCIS suppressor genes
Supplementary Figures 1-6 from Combined EGFR/MET or EGFR/HSP90 Inhibition Is Effective in the Treatment of Lung Cancers Codriven by Mutant EGFR Containing T790M and MET
Authors: Xu Lu , Kikuchi Eiki , Xu Chunxiao , Ebi Hiromichi , Ercan Dalia , Cheng Katherine A. , Padera Robert , Engelman Jeffrey A. , Jänne Pasi A. , Shapiro Geoffrey I. , Shimamura Takeshi , Wong Kwok-Kin
Published: March 2023

PDF file - 1.4MB, Supplemental Figure 1. MET is inducible in MET, TD/MET, and TL/MET models Supplemental Figure 2. Quantification of hMET expression in mouse models Supplemental Figure 3. Comparison of the tumor counts in mutant EGFR lung tumors with or without expression of hMET. Supplemental Figure 4. Representative MRI images prior to and after treatment in TL and TL/MET mice. Supplemental Figure 5. Xenografts of HCC827GR6 cells ectopically expressing EGFR E746_A750del/T790M are sensitive to the combination of WZ4002 and 17-DMAG. Supplemental Figure 6. The WZ4002/crizotinib or WZ4002/17-DMAG combinations suppress phosphorylation of EGFR, Akt, and Erk in TD and TD/MET to a greater extent than individual treatments
Supplementary Figure 8 from TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
Authors: Duvvuri Umamaheswar , Shiwarski Daniel J. , Xiao Dong , Bertrand Carol , Huang Xin , Edinger Robert S. , Rock Jason R. , Harfe Brian D. , Henson Brian J. , Kunzelmann Karl , Schreiber Rainer , Seethala Raja S. , Egloff Ann Marie , Chen Xing , Lui Vivian W. , Grandis Jennifer R. , Gollin Susanne M.
Published: March 2023

PDF file - 109K, TMEM16A inhibition with T16A-inh01 (A01) alone or in combination with the MEK/ERK inhibitor UO126 leads to decreased tumor cell viability in vitro. UM-SCC1 and T24 cells were treated with increasing concentrations of A01. A dose dependent reduction in cell viability was observed (A, B *P<0.05, **P<0.01, ***P<0.001). Additionally, treatment of SCC1 and T24 cells with TMEM16A shRNA led to a decrease in cell viability that in combination with inhibition of ERK1/2 had an additive effect (C, D; mean � SEM; n=4, *P<0.05, **P<0.01). The chemical structure of AO1 is shown in panel E.
Supplementary Figure 6 from TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
Authors: Duvvuri Umamaheswar , Shiwarski Daniel J. , Xiao Dong , Bertrand Carol , Huang Xin , Edinger Robert S. , Rock Jason R. , Harfe Brian D. , Henson Brian J. , Kunzelmann Karl , Schreiber Rainer , Seethala Raja S. , Egloff Ann Marie , Chen Xing , Lui Vivian W. , Grandis Jennifer R. , Gollin Susanne M.
Published: March 2023

PDF file - 101K, Cyclin D1 expression is reduced in the proliferating tissues derived from Tmem16a -/- mice when compared to wild-type littermates. Tissues harvested from Tmem16a -/- and wild-type mice were subjected to immunohistochemical staining for cyclin-D1. The proliferating mesoderm demonstrated intense nuclear staining of cyclin-D1 in wild-type mice, but not in knock-out littermates (A). Levels of cyclinD1 mRNA are correlated with TMEM16A expression in tissues derived from TMEM16A (-/-), (+/-) and (+/+) mice (B). TMEM16A overexpression did not induce activation of ERK5, another MAPK that can contribute to proliferation (C).
Supplementary Figure 2 from A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
Authors: Kulbe Hagen , Chakravarty Probir , Leinster D. Andrew , Charles Kellie A. , Kwong Joseph , Thompson Richard G. , Coward Jermaine I. , Schioppa Tiziana , Robinson Stephen C. , Gallagher William M. , Galletta Laura , Salako Michael A. , Smyth John F. , Hagemann Thorsten , Brennan Donal J. , Bowtell David D. , Balkwill Frances R.
Published: March 2023

PDF file - 279K
Supplementary Table 1 from A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
Authors: Waaler Jo , Machon Ondrej , Tumova Lucie , Dinh Huyen , Korinek Vladimir , Wilson Steven Ray , Paulsen Jan Erik , Pedersen Nina Marie , Eide Tor J. , Machonova Olga , Gradl Dietmar , Voronkov Andrey , von Kries Jens Peter , Krauss Stefan
Published: March 2023

XLS file - 574K, The table shows the results from an Illumina expression analysis that examined mRNA from SW480 CRC cells exposed to JW55 for 72 hours.
Supplementary Table 2 from Mammalian Sterile 20–like Kinase 1 Suppresses Lymphoma Development by Promoting Faithful Chromosome Segregation
Authors: Kim Tae-Shin , Lee Da-Hye , Kim Sang Kyum , Shin So Youn , Seo Eul-Ju , Lim Dae-Sik
Published: March 2023

PDF file - 19K, Characteristics of moribund p53-/-Mst1+/+ and p53-/-Mst1-/- mice
Supplementary Figure 3 from RANK Induces Epithelial–Mesenchymal Transition and Stemness in Human Mammary Epithelial Cells and Promotes Tumorigenesis and Metastasis
Authors: Palafox Marta , Ferrer Irene , Pellegrini Pasquale , Vila Sergi , Hernandez-Ortega Sara , Urruticoechea Ander , Climent Fina , Soler Maria Teresa , Muñoz Purificación , Viñals Francesc , Tometsko Mark , Branstetter Dan , Dougall William C. , González-Suárez Eva
Published: March 2023

PDF file - 72K, RANK overexpression induces mammary stem markers
Supplementary Figure 3 from Platelets and P-Selectin Control Tumor Cell Metastasis in an Organ-Specific Manner and Independently of NK Cells
Authors: Coupland Lucy A. , Chong Beng H. , Parish Christopher R.
Published: March 2023

PDF file, 320K, Tissue factor expression in B16F1 melanoma and 4T1.2 breast cancer cell lines.
Supplementary Figure 6 from Stromal Progenitor Cells from Endogenous Adipose Tissue Contribute to Pericytes and Adipocytes That Populate the Tumor Microenvironment
Authors: Zhang Yan , Daquinag Alexes C. , Amaya-Manzanares Felipe , Sirin Olga , Tseng Chieh , Kolonin Mikhail G.
Published: March 2023

PDF file - 2.4MB, ASC as perivascular cells in WAT and tumors
Supplementary Figure 1 from Frequent PVT1 Rearrangement and Novel Chimeric Genes PVT1-NBEA and PVT1-WWOX Occur in Multiple Myeloma with 8q24 Abnormality
Authors: Nagoshi Hisao , Taki Tomohiko , Hanamura Ichiro , Nitta Masakazu , Otsuki Takemi , Nishida Kazuhiro , Okuda Keiko , Sakamoto Natsumi , Kobayashi Satoru , Yamamoto-Sugitani Mio , Tsutsumi Yasuhiko , Kobayashi Tsutomu , Matsumoto Yosuke , Horiike Shigeo , Kuroda Junya , Taniwaki Masafumi
Published: March 2023

PDF file - 160K, FISH findings for interphase nuclei
Supplementary Table 2 from Stress-Regulated Transcription Factor ATF4 Promotes Neoplastic Transformation by Suppressing Expression of the INK4a/ARF Cell Senescence Factors
Authors: Horiguchi Michiko , Koyanagi Satoru , Okamoto Akinori , Suzuki Satoshi O. , Matsunaga Naoya , Ohdo Shigehiro
Published: March 2023

PDF file - 163K
supplementary Figure Legends 1-2 from NFAT1 Supports Tumor-induced Anergy of CD4+ T Cells
Authors: Abe Brian T. , Shin Daniel S. , Mocholi Enric , Macian Fernando
Published: March 2023

PDF file - 90K
Supplementary Tables 1-4, Figure 1 from The ABL Switch Control Inhibitor DCC-2036 Is Active against the Chronic Myeloid Leukemia Mutant BCR-ABLT315I and Exhibits a Narrow Resistance Profile
Authors: Eide Christopher A. , Adrian Lauren T. , Tyner Jeffrey W. , Mac Partlin Mary , Anderson David J. , Wise Scott C. , Smith Bryan D. , Petillo Peter A. , Flynn Daniel L. , Deininger Michael W.N. , O'Hare Thomas , Druker Brian J.
Published: March 2023

Supplementary Tables 1-4, Figure 1 from The ABL Switch Control Inhibitor DCC-2036 Is Active against the Chronic Myeloid Leukemia Mutant BCR-ABLT315I and Exhibits a Narrow Resistance Profile
Supplementary Figures 1-3 from Novel Transcriptional Targets of the SRY-HMG Box Transcription Factor SOX4 Link Its Expression to the Development of Small Cell Lung Cancer
Authors: Castillo Sandra D. , Matheu Ander , Mariani Niccolo , Carretero Julian , Lopez-Rios Fernando , Lovell-Badge Robin , Sanchez-Cespedes Montse
Published: March 2023

PDF file - 515K
Supplementary Figure Legends 1-8, Table Legends 1-3 from Novel Transcriptional Targets of the SRY-HMG Box Transcription Factor SOX4 Link Its Expression to the Development of Small Cell Lung Cancer
Authors: Castillo Sandra D. , Matheu Ander , Mariani Niccolo , Carretero Julian , Lopez-Rios Fernando , Lovell-Badge Robin , Sanchez-Cespedes Montse
Published: March 2023

PDF file - 78K
Supplementary Table 1 from High-Throughput RNAi Screening Reveals Novel Regulators of Telomerase
Authors: Cerone Maria Antonietta , Burgess Darren J , Naceur-Lombardelli Cristina , Lord Christopher J. , Ashworth Alan
Published: March 2023

Supplementary Table 1 from High-Throughput RNAi Screening Reveals Novel Regulators of Telomerase
Supplementary Table 2 from Candidate Pathways for Promoting Differentiation or Quiescence of Oligodendrocyte Progenitor-like Cells in Glioma
Authors: Dougherty Joseph D. , Fomchenko Elena I. , Akuffo Afua A. , Schmidt Eric , Helmy Karim Y. , Bazzoli Elena , Brennan Cameron W. , Holland Eric C. , Milosevic Ana
Published: March 2023

XLS file - 3.4MB, Lists of cell-type specific and enriched messages for all four human tumor classes. Four worksheets contain those genes specific to, or highly enriched in one of the four glioma classes (Specificity index p value <.05). The fifth worksheet has all data for all genes. SI: Specificity index. pSI: Specificity Index p-Value
Supplementary Figure 3 from Expression of P2X7 Receptor Increases In Vivo Tumor Growth
Authors: Adinolfi Elena , Raffaghello Lizzia , Giuliani Anna Lisa , Cavazzini Luigi , Capece Marina , Chiozzi Paola , Bianchi Giovanna , Kroemer Guido , Pistoia Vito , Di Virgilio Francesco
Published: March 2023

PDF file, 56KB, Fig. S3. Effect of P2X7 inhibition on B16 melanoma growth. Panel A, comparison of basal P2X7 expression in HEK293-mock, CT26wt and B16 tumor cell lines. Cell protein was extracted, run on SDS PAGE, blotted and stained with a cross-reactive human and mouse P2X7-selective polyclonal Ab. Panel B, size of B16 tumor masses injected with 300 nM AZ10606120 in 100 μl of sterile water, or just sterile water, and excised at d 15 (n=7); * p <0.05 versus control B16.
Supplementary Table 1 from Candidate Pathways for Promoting Differentiation or Quiescence of Oligodendrocyte Progenitor-like Cells in Glioma
Authors: Dougherty Joseph D. , Fomchenko Elena I. , Akuffo Afua A. , Schmidt Eric , Helmy Karim Y. , Bazzoli Elena , Brennan Cameron W. , Holland Eric C. , Milosevic Ana
Published: March 2023

XLS file - 6.3MB, Lists of cell-type specific and enriched messages for all four cell types. Four worksheets contain those genes specific to, or highly enriched in one of the four cell types (Specificity index p value <.05). The fifth worksheet has all data for all genes. SI: Specificity index. pSI: Specificity Index p-Value
Supplementary Figure 2 from Expression of P2X7 Receptor Increases In Vivo Tumor Growth
Authors: Adinolfi Elena , Raffaghello Lizzia , Giuliani Anna Lisa , Cavazzini Luigi , Capece Marina , Chiozzi Paola , Bianchi Giovanna , Kroemer Guido , Pistoia Vito , Di Virgilio Francesco
Published: March 2023

PDF file, 88KB, Fig. S2. Effect of P2X7 expression on the growth of CT26 colon carcinoma. Panel A, detection of mP2X7 by semiquantitative PCR and Western blot in CT26-wt cells and in three stably transfected clones (CT26-mP2X7c1, c2, and c3). G3PDH and actin are shown as housekeeping control gene and protein, respectively. Panel B, representative sizes of tumor masses excised at d 15 post-inoculum. Panel C, average � SE volumes of excised tumor masses; green, CT26wt (n=10); black, CT26-mP2X7c1( n=10) ; red, CT26-mP2X7c2 (n=10); blue, CT26-mP2X7c3 (n=10). * p <0.05 versus CT26-wt.
Supplementary Figure 4 from Candidate Pathways for Promoting Differentiation or Quiescence of Oligodendrocyte Progenitor-like Cells in Glioma
Authors: Dougherty Joseph D. , Fomchenko Elena I. , Akuffo Afua A. , Schmidt Eric , Helmy Karim Y. , Bazzoli Elena , Brennan Cameron W. , Holland Eric C. , Milosevic Ana
Published: March 2023

PDF file - 111K, Human Proneural tumors are relatively enriched in OPC genes. Expression profiles of 202 gliomas from TCGARN were analyzed, grouped into the four subclasses (2) A: Using gene symbol to map human and mouse homologues, highly significant enrichment of OPC genes in the human 'proneural' specific gene lists was identified (Chi-square p < 5E-31), but not in the other human glioma gene lists. Percent of tumor subclass specific gene lists overlapping with OPC specific genes. **** p<1E-32, + p<.06, Chi-square. All gene lists used pSI<.01 as a cut-off. B: Hierarchical clustering with just OPC genes is sufficient to distinguish most proneural tumors from other tumor subtypes. C: Expression level of average of OPC genes is higher in 'proneural' tumors though they are present at detectable levels in all subtypes. *p<.003, **p<.003, ***p<1E-7, ANOVA with Tukey Post Hocs.
Supplementary Figure 6 from Histone Deacetylase Inhibitors Influence Chemotherapy Transport by Modulating Expression and Trafficking of a Common Polymorphic Variant of the ABCG2 Efflux Transporter
Authors: Basseville Agnes , Tamaki Akina , Ierano Caterina , Trostel Shana , Ward Yvona , Robey Robert W. , Hegde Ramanujan S. , Bates Susan E.
Published: March 2023

PDF file - 26K, Chaperone expression after HDI treatment
Supplementary Figure 5 from Histone Deacetylase Inhibitors Influence Chemotherapy Transport by Modulating Expression and Trafficking of a Common Polymorphic Variant of the ABCG2 Efflux Transporter
Authors: Basseville Agnes , Tamaki Akina , Ierano Caterina , Trostel Shana , Ward Yvona , Robey Robert W. , Hegde Ramanujan S. , Bates Susan E.
Published: March 2023

PDF file - 29K, Impact of CHX and actinomycin D on HDI-induced ABCG2 surface overexpression
Supplementary Figure 1 from Histone Deacetylase Inhibitors Influence Chemotherapy Transport by Modulating Expression and Trafficking of a Common Polymorphic Variant of the ABCG2 Efflux Transporter
Authors: Basseville Agnes , Tamaki Akina , Ierano Caterina , Trostel Shana , Ward Yvona , Robey Robert W. , Hegde Ramanujan S. , Bates Susan E.
Published: March 2023

PDF file - 47K, Effect of inhibition of autophagy on ABCG2 expression
Supplementary Table 2 from 53BP1 Is a Haploinsufficient Tumor Suppressor and Protects Cells from Radiation Response in Glioma
Authors: Squatrito Massimo , Vanoli Fabio , Schultz Nikolaus , Jasin Maria , Holland Eric C.
Published: March 2023

XLS file - 66K, Co-occurrence of TP53BP1 and TP53 alterations in the TCGA dataset for GBM
Supplementary Figure 3 from 53BP1 Is a Haploinsufficient Tumor Suppressor and Protects Cells from Radiation Response in Glioma
Authors: Squatrito Massimo , Vanoli Fabio , Schultz Nikolaus , Jasin Maria , Holland Eric C.
Published: March 2023

PDF file - 22K, 53BP1 silencing does not increase TMZ sensitivity in T98G cells
Supplementary Figure 4 from Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
Authors: Nagahashi Masayuki , Ramachandran Subramaniam , Kim Eugene Y. , Allegood Jeremy C. , Rashid Omar M. , Yamada Akimitsu , Zhao Renping , Milstien Sheldon , Zhou Huiping , Spiegel Sarah , Takabe Kazuaki
Published: March 2023

PDF file - 7.4MB, SK1-I reduces recruitment of macrophages to peritumoral regions. Immunofluorescent staining of macrophages in the peritumoral region with F4/80. LYVE-1+ staining revealed only very little co-staining with F4/80.
Supplementary Table 5 from Biomarkers of HPV in Head and Neck Squamous Cell Carcinoma
Authors: Liang Caihua , Marsit Carmen J. , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Haddad Robert I. , Clark John R. , Wein Richard O. , Grillone Gregory A. , Houseman E. Andres , Halec Gordana , Waterboer Tim , Pawlita Michael , Krane Jeffrey F. , Kelsey Karl T.
Published: March 2023

PDF file - 65K, The association between selected markers and overall survival of HNSSC patients with and without adjustment for tumor stages, Eastern Massachusetts, 1999-2003
Supplementary Figure 1 from Distinctive Features of the Differentiated Phenotype and Infiltration of Tumor-Reactive Lymphocytes in Clear Cell Renal Cell Carcinoma
Authors: Wang Qiong J. , Hanada Ken-ichi , Robbins Paul F. , Li Yong F. , Yang James C.
Published: March 2023

PDF file - 30K, Correlation between CD70 expression (Mean fluorescence intensity; MFI) and RCC T cell phenotype. T cells from renal tumors were labeled the same as shown in Figure 1, and Lin 1- cells from renal tumors were labeled the same as shown in Figure 2. R=0.3; P=0.08
Supplementary Figures 1-3 from Tpx2 Controls Spindle Integrity, Genome Stability, and Tumor Development
Authors: Aguirre-Portolés Cristina , Bird Alexander W. , Hyman Anthony , Cañamero Marta , Pérez de Castro Ignacio , Malumbres Marcos
Published: March 2023

PDF file - 224K, Supplemental data includes three figures with a detailed description of the cell cycle characteristics of Tpx2(+/-) cells, quantification of tubulin staining in Tpx2-null embryonic cells and levels of Tpx2 mRNA levels in different tissues from Tpx2(+/-) mice.
Supplementary Table 1 from Temporal Molecular and Biological Assessment of an Erlotinib-Resistant Lung Adenocarcinoma Model Reveals Markers of Tumor Progression and Treatment Response
Authors: Weaver Zoë , Difilippantonio Simone , Carretero Julian , Martin Philip L. , El Meskini Rajaa , Iacovelli Anthony J. , Gumprecht Michelle , Kulaga Alan , Guerin Theresa , Schlomer Jerome , Baran Maureen , Kozlov Serguei , McCann Thomas , Mena Salvador , Al-Shahrour Fatima , Alexander Danny , Wong Kwok-Kin , Van Dyke Terry
Published: March 2023

PDF file - 91K, Number of altered biochemicals and directional changes in the tumor induction experiment
Supplementary Figure 3 from Cathepsin B Inhibition Limits Bone Metastasis in Breast Cancer
Authors: Withana Nimali P. , Blum Galia , Sameni Mansoureh , Slaney Clare , Anbalagan Arulselvi , Olive Mary B. , Bidwell Bradley N. , Edgington Laura , Wang Ling , Moin Kamiar , Sloane Bonnie F. , Anderson Robin L. , Bogyo Matthew S. , Parker Belinda S.
Published: March 2023

PDF file - 2.5MB
Supplementary Table 1 from An Insertion/Deletion Polymorphism within RERT-lncRNA Modulates Hepatocellular Carcinoma Risk
Authors: Zhu Zhansheng , Gao Xueren , He Yan , Zhao Hua , Yu Qiang , Jiang Deke , Zhang Pingzhao , Ma Xiaopin , Huang Huixing , Dong Dong , Wan Jiao , Gu Zhenyong , Jiang Xinghong , Yu Long , Gao Yuzhen
Published: March 2023

PDF file - 46K, Primers sequences used in this study
Supplementary Figure 3 from Coxsackievirus B3 Is an Oncolytic Virus with Immunostimulatory Properties That Is Active against Lung Adenocarcinoma
Authors: Miyamoto Shohei , Inoue Hiroyuki , Nakamura Takafumi , Yamada Meiko , Sakamoto Chika , Urata Yasuo , Okazaki Toshihiko , Marumoto Tomotoshi , Takahashi Atsushi , Takayama Koichi , Nakanishi Yoichi , Shimizu Hiroyuki , Tani Kenzaburo
Published: March 2023

PDF file - 96K, Remarkable CVB3 induced suppression of H1299 human tumor growth in mice.
Supplementary Table 4 from Oncolytic Immunotherapy of Advanced Solid Tumors with a CD40L-Expressing Replicating Adenovirus: Assessment of Safety and Immunologic Responses in Patients
Authors: Pesonen Sari , Diaconu Iulia , Kangasniemi Lotta , Ranki Tuuli , Kanerva Anna , Pesonen Saila K. , Gerdemann Ulrike , Leen Ann M. , Kairemo Kalevi , Oksanen Minna , Haavisto Elina , Holm Sirkka-Liisa , Karioja-Kallio Aila , Kauppinen Satu , Partanen Kaarina P. L. , Laasonen Leena , Joensuu Tima , Alanko Tuomo , Cerullo Vincenzo , Hemminki Akseli
Published: March 2023

PDF file - 69K, Description of historical controls (Pesonen et al. Gene Ther 2010;17:892-904) treated with unarmed oncolytic adenovirus Ad5/3-cox2L-D24.
Supplementary Tables 1-11 from Integrative Genomic Analyses of Sporadic Clear Cell Renal Cell Carcinoma Define Disease Subtypes and Potential New Therapeutic Targets
Authors: Dondeti Vijay R. , Wubbenhorst Bradley , Lal Priti , Gordan John D. , D'Andrea Kurt , Attiyeh Edward F. , Simon M. Celeste , Nathanson Katherine L.
Published: March 2023

PDF file - 130K
Supplementary Figures 1-3 from IL-10 Directly Activates and Expands Tumor-Resident CD8+ T Cells without De Novo Infiltration from Secondary Lymphoid Organs
Authors: Emmerich Jan , Mumm John B. , Chan Ivan H. , LaFace Drake , Truong Hoa , McClanahan Terrill , Gorman Daniel M. , Oft Martin
Published: March 2023

PDF file - 206K, Suppl. Figure 1. PEG-IL-10 increases intratumoral CD8 T cells and induces CD8 T cell dependent tumor rejection. Suppl. Figure 2. Anti-tumor efficacy is abolished in IL-10R-/- mice. Suppl Figure 3. FTY720 treatment neither impairs IL-10 induced activation of tumor-resident CD8+ T cells nor rejection of CT26 tumors
Supplementary Figure Legends 1-4 from Critical Function for Nuclear Envelope Protein TMEM209 in Human Pulmonary Carcinogenesis
Authors: Fujitomo Takashi , Daigo Yataro , Matsuda Koichi , Ueda Koji , Nakamura Yusuke
Published: March 2023

PDF file - 72K
Supplementary Figure 4 from IKK-ϵ Coordinates Invasion and Metastasis of Ovarian Cancer
Authors: Hsu Sarah , Kim Marianne , Hernandez Lidia , Grajales Valentina , Noonan Anne , Anver Miriam , Davidson Ben , Annunziata Christina M.
Published: March 2023

PDF file - 1.8MB
Supplementary Figure 3 from IKK-ϵ Coordinates Invasion and Metastasis of Ovarian Cancer
Authors: Hsu Sarah , Kim Marianne , Hernandez Lidia , Grajales Valentina , Noonan Anne , Anver Miriam , Davidson Ben , Annunziata Christina M.
Published: March 2023

PDF file - 233K, Viability and invasion of additional ovarian cancer cell lines
Supplementary Figure 4 from Dysfunction of Nucleus Accumbens-1 Activates Cellular Senescence and Inhibits Tumor Cell Proliferation and Oncogenesis
Authors: Zhang Yi , Cheng Yan , Ren Xingcong , Hori Tsukasa , Huber-Keener Kathryn J. , Zhang Li , Yap Kai Lee , Liu David , Shantz Lisa , Qin Zheng-Hong , Zhang Suping , Wang Jianrong , Wang Hong-Gang , Shih Ie-Ming , Yang Jin-Ming
Published: March 2023

PDF file - 83K, Expression of p15, p16 and p18 in NAC1-activated or -inactivated tumor cells with or without irradiation treatment
Supplementary Methods from CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells
Authors: De Falco Valentina , Tamburrino Anna , Ventre Simona , Castellone Maria Domenica , Malek Mouhannad , Manié Serge N. , Santoro Massimo
Published: March 2023

PDF file - 117K
Supplementary Figure 8 from LIGHT Delivery to Tumors by Mesenchymal Stem Cells Mobilizes an Effective Antitumor Immune Response
Authors: Zou Weibin , Zheng Huilin , He Tong-Chuan , Chang Jinjia , Fu Yang-Xin , Fan Weimin
Published: March 2023

PDF file - 1.5MB, Matrigel plugs migration assay in prophylactic setting
Supplementary Table 2 from Chromogranin A Regulates Tumor Self-Seeding and Dissemination
Authors: Dondossola Eleonora , Crippa Luca , Colombo Barbara , Ferrero Elisabetta , Corti Angelo
Published: March 2023

PDF file - 440K
Supplementary Figure 5 from Chromogranin A Regulates Tumor Self-Seeding and Dissemination
Authors: Dondossola Eleonora , Crippa Luca , Colombo Barbara , Ferrero Elisabetta , Corti Angelo
Published: March 2023

PDF file - 71K
Supplementary Figure 2 from Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Authors: Verbrugge Inge , Hagekyriakou Jim , Sharp Leslie L. , Galli Mara , West Alison , McLaughlin Nicole M. , Duret Hélène , Yagita Hideo , Johnstone Ricky W. , Smyth Mark J. , Haynes Nicole M.
Published: March 2023

PDF file - 233K, Analysis of the combined therapeutic effects of radiotherapy and alpha-CD137/alpha-CD40 therapy in established 4T1.2 tumors
Supplementary Figure 1 from Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Authors: Verbrugge Inge , Hagekyriakou Jim , Sharp Leslie L. , Galli Mara , West Alison , McLaughlin Nicole M. , Duret Hélène , Yagita Hideo , Johnstone Ricky W. , Smyth Mark J. , Haynes Nicole M.
Published: March 2023

PDF file - 208K, Dose-finding experiments comparing the relative sensitivity of established 4T1.2 (A) and AT-3 (B) tumors to ionizing radiation
Supplementary Table 2 from Concordant Release of Glycolysis Proteins into the Plasma Preceding a Diagnosis of ER+ Breast Cancer
Authors: Amon Lynn M. , Pitteri Sharon J. , Li Christopher I. , McIntosh Martin , Ladd Jon J. , Disis Mary , Porter Peggy , Wong Chee Hong , Zhang Qing , Lampe Paul , Prentice Ross L. , Hanash Samir M.
Published: March 2023

PDF file - 52K
Supplementary Figure 1 from AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family
Authors: Gavine Paul R. , Mooney Lorraine , Kilgour Elaine , Thomas Andrew P. , Al-Kadhimi Katherine , Beck Sarah , Rooney Claire , Coleman Tanya , Baker Dawn , Mellor Martine J. , Brooks A. Nigel , Klinowska Teresa
Published: March 2023

PDF file - 68K
Supplementary Methods, Legends for Figures 1-4, Tables 1-5 from Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Authors: Tang Xiaohu , Lucas Joseph E. , Chen Julia Ling-Yu , LaMonte Gregory , Wu Jianli , Wang Michael Changsheng , Koumenis Constantinos , Chi Jen-Tsan
Published: March 2023

PDf file - 74K
Supplementary Figure 4 from Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells
Authors: Surget Sylvanie , Chiron David , Gomez-Bougie Patricia , Descamps Géraldine , Ménoret Emmanuelle , Bataille Régis , Moreau Philippe , Le Gouill Steven , Amiot Martine , Pellat-Deceunynck Catherine
Published: March 2023

PDF file - 137K, Nutlin3a increased DR5 expression via p53
Supplementary Figure 3 from Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells
Authors: Surget Sylvanie , Chiron David , Gomez-Bougie Patricia , Descamps Géraldine , Ménoret Emmanuelle , Bataille Régis , Moreau Philippe , Le Gouill Steven , Amiot Martine , Pellat-Deceunynck Catherine
Published: March 2023

PDF file - 49K, Nutlin-3a did not increase activation or recruitment of caspase 8 within DR4 DISC
Supplementary Figure 1 from Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
Authors: Carothers Adelaide M. , Rizvi Hira , Hasson Rian M. , Heit Yvonne I. , Davids Jennifer S. , Bertagnolli Monica M. , Cho Nancy L.
Published: March 2023

PDF file - 5.4MB, Examples of matching normal adjacent fascia. Sections from different patients are shown that stained negatively for MSC markers, CD90 (Left) and CD73 (Right), at 20X and 10X original magnifications.
Supplementary Methods and Figure Legend from Ikk4a/Arf Inactivation with Activation of the NF-κB/IL-6 Pathway Is Sufficient to Drive the Development and Growth of Angiosarcoma
Authors: Yang Jinming , Kantrow Sara , Sai Jiqing , Hawkins Oriana E. , Boothby Mark , Ayers Gregory D. , Young Eric D. , Demicco Elizabeth G. , Lazar Alexander J. , Lev Dina , Richmond Ann
Published: March 2023

PDF file, 154K.
Supplementary Figures 1 - 7, Table 1 from Ikk4a/Arf Inactivation with Activation of the NF-κB/IL-6 Pathway Is Sufficient to Drive the Development and Growth of Angiosarcoma
Authors: Yang Jinming , Kantrow Sara , Sai Jiqing , Hawkins Oriana E. , Boothby Mark , Ayers Gregory D. , Young Eric D. , Demicco Elizabeth G. , Lazar Alexander J. , Lev Dina , Richmond Ann
Published: March 2023

PDF file, 308K, Supplemental Figure S1. Tumoral IL-6 promotes angiosarcoma growth. Supplemental Figure S2. IL-6 triggers Stat3 signal pathway and impacts tumor immunity. Supplemental Figure S3. Immune cell migration is Ikkβ dependent and IL-6 independent. Supplemental Figure S4. Deletion of Ikk in myeloid cells impairs myeloid migration in response to tumor in vivo. Supplemental Figure S5. Systemic targeting of Ikkβ/Stat3/IL-6 in vivo. Supplemental Figure S7. Tumor induced myeloid cell chemoattraction assay in vivo. Supplemental Table S1. Myeloid IKKβ impacts angiosarcoma incidence and latency. Supplemental Table S2. Alignment of κB sequence from murine gp130, JAK2 and IL-6 promoters.
Supplementary Video 3 from RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization
Authors: Lee Seunghyung , Wurtzel Jeremy G. T. , Singhal Sharad S. , Awasthi Sanjay , Goldfinger Lawrence E.
Published: March 2023

MOV file - 948K, 3D muCT reconstruction of the vasculature in a LLC tumor derived in a wild type mouse
Supplementary Video 1 from RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization
Authors: Lee Seunghyung , Wurtzel Jeremy G. T. , Singhal Sharad S. , Awasthi Sanjay , Goldfinger Lawrence E.
Published: March 2023

MOV file - 983K, 3D muCT reconstruction of the vasculature in a B16F10 tumor derived in a wild type mouse
Supplementary Figure Legends 1-5, Video Legends 1-4 from RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization
Authors: Lee Seunghyung , Wurtzel Jeremy G. T. , Singhal Sharad S. , Awasthi Sanjay , Goldfinger Lawrence E.
Published: March 2023

Supplementary Figure Legends 1-5, Video Legends 1-4 from RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization
Supplementary Figure 4 from RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization
Authors: Lee Seunghyung , Wurtzel Jeremy G. T. , Singhal Sharad S. , Awasthi Sanjay , Goldfinger Lawrence E.
Published: March 2023

PDF file - 32K, Vascular volumes in tumors derived from the knockdown cells in RLIP76-/- or WT mice
Supplementary Figure 6 from Increased Survival of Glioblastoma Patients Who Respond to Antiangiogenic Therapy with Elevated Blood Perfusion
Authors: Sorensen A. Gregory , Emblem Kyrre E. , Polaskova Pavlina , Jennings Dominique , Kim Heisoog , Ancukiewicz Marek , Wang Meiyun , Wen Patrick Y. , Ivy Percy , Batchelor Tracy T. , Jain Rakesh K.
Published: March 2023

PDF file - 680K, Figure S6: Reproducibility Analysis. Bland-Altman plots showing (A) the test-retest variability of measurement of microvessel flow (Pearson correlation; �=1.00) and (B) the variability of flow measurement between the day -5 scan and the day -1 scan (two baselines) (�=0.93).
Supplementary Figure 1 from Caveolin-1 Increases Aerobic Glycolysis in Colorectal Cancers by Stimulating HMGA1-Mediated GLUT3 Transcription
Authors: Ha Tae-Kyu , Her Nam-Gu , Lee Min-Goo , Ryu Byung-Kyu , Lee Jin-Hee , Han Jikhyon , Jeong Seong-In , Kang Min-Ju , Kim Nam-Hoon , Kim Hyo-Jong , Chi Sung-Gil
Published: March 2023

PDF file- 92K, Expression and function of CAV1 in colorectal cancers
Supplementary Figure Legends 1-5 from Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments
Authors: Liu Wei , Glunde Kristine , Bhujwalla Zaver M. , Raman Venu , Sharma Anit , Phang James M.
Published: March 2023

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Supplementary Figure 4 from Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments
Authors: Liu Wei , Glunde Kristine , Bhujwalla Zaver M. , Raman Venu , Sharma Anit , Phang James M.
Published: March 2023

PDF file - 77K, Western blot confirms the knockdown of POX by siRNA in HT29 cells
Supplementary Figures 1-6, Table 1 from p53 Inhibits Angiogenesis by Inducing the Production of Arresten
Authors: Assadian Sarah , El-Assaad Wissal , Wang Xue Q.D. , Gannon Phillipe O. , Barrès Véronique , Latour Mathieu , Mes-Masson Anne-Marie , Saad Fred , Sado Yoshikazu , Dostie Josée , Teodoro Jose G.
Published: March 2023

PDF file - 465K
Supplementary Figure 5 from An NMR Metabolomics Approach for the Diagnosis of Leptomeningeal Carcinomatosis
Authors: Cho Hye Rim , Wen He , Ryu Young Jin , An Yong Jin , Kim Hyo Cheol , Moon Woo Kyung , Han Moon Hee , Park Sunghyouk , Choi Seung Hong
Published: March 2023

PDF file - 121K, Correlation between the NMR spectral markers and the thickness of the LC infiltration in the 7 day-LC animals
Supplementary Data 4 from An NMR Metabolomics Approach for the Diagnosis of Leptomeningeal Carcinomatosis
Authors: Cho Hye Rim , Wen He , Ryu Young Jin , An Yong Jin , Kim Hyo Cheol , Moon Woo Kyung , Han Moon Hee , Park Sunghyouk , Choi Seung Hong
Published: March 2023

PDF file - 66K, The absolute concentration of the marker metabolites at each experimental time points
Supplementary Figure 5 from Acyclic Retinoid Targets Platelet-Derived Growth Factor Signaling in the Prevention of Hepatic Fibrosis and Hepatocellular Carcinoma Development
Authors: Okada Hikari , Honda Masao , Campbell Jean S. , Sakai Yoshio , Yamashita Taro , Takebuchi Yuuki , Hada Kazuhiro , Shirasaki Takayoshi , Takabatake Riuta , Nakamura Mikiko , Sunagozaka Hajime , Tanaka Takuji , Fausto Nelson , Kaneko Shuichi
Published: March 2023

PDF file - 2MB, The core gene network consisting 41 representative growth factors, receptors (PDGFR and TGFI3R etc) and transcriptional factors. Sp1 and Ap1 could be the "hub", key regulators in the network.
Supplementary Methods from ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
Authors: Clegg Nicola J. , Wongvipat John , Joseph James D. , Tran Chris , Ouk Samedy , Dilhas Anna , Chen Yu , Grillot Kate , Bischoff Eric D. , Cai Ling , Aparicio Anna , Dorow Steven , Arora Vivek , Shao Gang , Qian Jing , Zhao Hong , Yang Guangbin , Cao Chunyan , Sensintaffar John , Wasielewska Teresa , Herbert Mark R. , Bonnefous Celine , Darimont Beatrice , Scher Howard I. , Smith-Jones Peter , Klang Mark , Smith Nicholas D. , De Stanchina Elisa , Wu Nian , Ouerfelli Ouathek , Rix Peter J. , Heyman Richard A. , Jung Michael E. , Sawyers Charles L. , Hager Jeffrey H.
Published: March 2023

PDF file - 181K
Supplementary Figure 3 from ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
Authors: Clegg Nicola J. , Wongvipat John , Joseph James D. , Tran Chris , Ouk Samedy , Dilhas Anna , Chen Yu , Grillot Kate , Bischoff Eric D. , Cai Ling , Aparicio Anna , Dorow Steven , Arora Vivek , Shao Gang , Qian Jing , Zhao Hong , Yang Guangbin , Cao Chunyan , Sensintaffar John , Wasielewska Teresa , Herbert Mark R. , Bonnefous Celine , Darimont Beatrice , Scher Howard I. , Smith-Jones Peter , Klang Mark , Smith Nicholas D. , De Stanchina Elisa , Wu Nian , Ouerfelli Ouathek , Rix Peter J. , Heyman Richard A. , Jung Michael E. , Sawyers Charles L. , Hager Jeffrey H.
Published: March 2023

PDF file- 366K
Supplementary Figures 1-6, Methods from Defective NF-κB Signaling in Metastatic Head and Neck Cancer Cells Leads to Enhanced Apoptosis by Double-Stranded RNA
Authors: Umemura Naoki , Zhu Jianzhong , Mburu Yvonne K. , Forero Adriana , Hsieh Paishiun N. , Muthuswamy Ravikumar , Kalinski Pawel , Ferris Robert L. , Sarkar Saumendra N.
Published: March 2023

PDF file - 520K
Supplementary Figure 1 from ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
Authors: Clegg Nicola J. , Wongvipat John , Joseph James D. , Tran Chris , Ouk Samedy , Dilhas Anna , Chen Yu , Grillot Kate , Bischoff Eric D. , Cai Ling , Aparicio Anna , Dorow Steven , Arora Vivek , Shao Gang , Qian Jing , Zhao Hong , Yang Guangbin , Cao Chunyan , Sensintaffar John , Wasielewska Teresa , Herbert Mark R. , Bonnefous Celine , Darimont Beatrice , Scher Howard I. , Smith-Jones Peter , Klang Mark , Smith Nicholas D. , De Stanchina Elisa , Wu Nian , Ouerfelli Ouathek , Rix Peter J. , Heyman Richard A. , Jung Michael E. , Sawyers Charles L. , Hager Jeffrey H.
Published: March 2023

PDF file - 312K
Supplementary Table 1 from The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
Authors: De Bacco Francesca , Casanova Elena , Medico Enzo , Pellegatta Serena , Orzan Francesca , Albano Raffaella , Luraghi Paolo , Reato Gigliola , D'Ambrosio Antonio , Porrati Paola , Patanè Monica , Maderna Emanuela , Pollo Bianca , Comoglio Paolo M. , Finocchiaro Gaetano , Boccaccio Carla
Published: March 2023

XLS file - 12K, Mutations of PTEN, TP53, and NF1 genes in glioblastoma neurospheres
Supplementary Table 3 from Leptin and Soluble Leptin Receptor in Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition Cohort
Authors: Aleksandrova Krasimira , Boeing Heiner , Jenab Mazda , Bueno-de-Mesquita H. Bas , Jansen Eugene , van Duijnhoven Fränzel J. B. , Rinaldi Sabina , Fedirko Veronika , Romieu Isabelle , Riboli Elio , Gunter Marc J. , Westphal Sabine , Overvad Kim , Tjønneland Anne , Halkjær Jytte , Racine Antoine , Boutron-Ruault Marie-Christine , Clavel-Chapelon Françoise , Kaaks Rudolf , Lukanova Annekatrin , Trichopoulou Antonia , Lagiou Pagona , Trichopoulos Dimitrios , Mattiello Amalia , Pala Valeria , Palli Domenico , Tumino Rosario , Vineis Paolo , Buckland Genevieve , Sánchez María-José , Amiano Pilar , Huerta José María , Barricarte Aurelio , Menéndez Virginia , Peeters Petra H. , Söderberg Stefan , Palmqvist Richard , Allen Naomi E. , Crowe Francesca L. , Khaw Kay-Tee , Wareham Nickolas , Pischon Tobias
Published: March 2023

PDF file - 127K, Relative risks (RR-s)* and 95% confidence intervals (CI-s) of colorectal cancer associated with a doubling in leptin and sOB-R concentrations, by subgroups, the European Prospective Investigation into Cancer and Nutrition (EPIC), 1992-2003
Supplementary Table 2 from Leptin and Soluble Leptin Receptor in Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition Cohort
Authors: Aleksandrova Krasimira , Boeing Heiner , Jenab Mazda , Bueno-de-Mesquita H. Bas , Jansen Eugene , van Duijnhoven Fränzel J. B. , Rinaldi Sabina , Fedirko Veronika , Romieu Isabelle , Riboli Elio , Gunter Marc J. , Westphal Sabine , Overvad Kim , Tjønneland Anne , Halkjær Jytte , Racine Antoine , Boutron-Ruault Marie-Christine , Clavel-Chapelon Françoise , Kaaks Rudolf , Lukanova Annekatrin , Trichopoulou Antonia , Lagiou Pagona , Trichopoulos Dimitrios , Mattiello Amalia , Pala Valeria , Palli Domenico , Tumino Rosario , Vineis Paolo , Buckland Genevieve , Sánchez María-José , Amiano Pilar , Huerta José María , Barricarte Aurelio , Menéndez Virginia , Peeters Petra H. , Söderberg Stefan , Palmqvist Richard , Allen Naomi E. , Crowe Francesca L. , Khaw Kay-Tee , Wareham Nickolas , Pischon Tobias
Published: March 2023

PDF file - 80K, Relative risks (RR-s) and 95% confidence intervals (CI-s) of colon, rectal and colorectal cancer according to quintiles of free leptin index (FLI), the European Prospective Investigation into Cancer and Nutrition (EPIC), 1992-2003
Supplementary Table 1 from BCL2 Suppresses PARP1 Function and Nonapoptotic Cell Death
Authors: Dutta Chaitali , Day Tovah , Kopp Nadja , van Bodegom Diederik , Davids Matthew S. , Ryan Jeremy , Bird Liat , Kommajosyula Naveen , Weigert Oliver , Yoda Akinori , Fung Hua , Brown Jennifer R. , Shapiro Geoffrey I. , Letai Anthony , Weinstock David M.
Published: March 2023

PDF file - 19K, Peptides recovered from immunprecipitation of BCL2 from the chromatin fraction of irradiated cells that matched PARP1 with at least 99% confidence
Supplementary Table 3 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Authors: Hilvo Mika , Denkert Carsten , Lehtinen Laura , Müller Berit , Brockmöller Scarlet , Seppänen-Laakso Tuulikki , Budczies Jan , Bucher Elmar , Yetukuri Laxman , Castillo Sandra , Berg Emilia , Nygren Heli , Sysi-Aho Marko , Griffin Julian L. , Fiehn Oliver , Loibl Sibylle , Richter-Ehrenstein Christiane , Radke Cornelia , Hyötyläinen Tuulia , Kallioniemi Olli , Iljin Kristiina , Orešič Matej
Published: March 2023

Supplementary Table 3 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Supplementary Table 1 from FGFR2 Isoforms Support Epithelial–Stromal Interactions in Thyroid Cancer Progression
Authors: Guo Miao , Liu Wei , Serra Stefano , Asa Sylvia L. , Ezzat Shereen
Published: March 2023

PDF file - 368K
Supplementary Figure Legends 1-4 from The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth
Authors: Luo Zhongguang , Yu Guangyang , Lee Hyuk Woo , Li Lihui , Wang Lingyan , Yang Dongqin , Pan Yongfu , Ding Chan , Qian Jing , Wu Lijun , Chu Yiwei , Yi Jing , Wang Xiangdong , Sun Yi , Jeong Lak Shin , Liu Jie , Jia Lijun
Published: March 2023

PDF file - 94K
Supplementary Figures 1-7 from Deficiency in Mammalian Histone H2B Ubiquitin Ligase Bre1 (Rnf20/Rnf40) Leads to Replication Stress and Chromosomal Instability
Authors: Chernikova Sophia B. , Razorenova Olga V. , Higgins John P. , Sishc Brock J. , Nicolau Monica , Dorth Jennifer A. , Chernikova Diana A. , Kwok Shirley , Brooks James D. , Bailey Susan M. , Game John C. , Brown J. Martin
Published: March 2023

PDF file - 591K
Supplementary Figure 6 from SIRT1 Pathway Dysregulation in the Smoke-Exposed Airway Epithelium and Lung Tumor Tissue
Authors: Beane Jennifer , Cheng Luis , Soldi Raffaella , Zhang Xiaohui , Liu Gang , Anderlind Christina , Lenburg Marc E. , Spira Avrum , Bild Andrea H.
Published: March 2023

PDF file, 38K, SIRT1 copy number changes in the Cancer Cell Line Encyclopedia (CCLE) dataset. The dataset consists of both gene expression (measured by Affymetrix HGU133 Plus 2.0 microarrays) and DNA copy number data (measured by Affymetrix SNP 6.0 microarrays) across 991 cancer cell lines. A. Across the 174 lung cancer cell lines, copy number values for SIRT1 in the CCLE dataset are in the insignificant range (dark gray, from -1 to 1), indicating that there is not a loss or amplification of the SIRT1 locus in lung tumors; in contrast, the values for MYC, range from -1 to 3 (light gray). B. SIRT1 and C. MYC pathway activation were predicted across the cancer cell lines using the SIRT1 signature and a MYC signature derived in human mammary epithelial cells (17). There is a significant Pearson correlation between MYC pathway activation and MYC copy number (r=0.51, p<<0.001) but not between SIRT1 pathway activation and SIRT1 copy number (r=0.14, p=0.07), suggesting that decreases in SIRT1 pathway activation are not due to copy loss at the locus. The results are derived by performing RMA as described in the manuscript using the ENTREZ Gene CDF file on each of the 14 batches of CCLE CEL files. Pathway predictions were made using either the SIRT1 or MYC signature across each batch of the CCLE dataset, the predictions from each batch were combined, and lung cancer cell lines were separated out for the analyses in B and C.
Supplementary Figure Legends from Plastin3 Is a Novel Marker for Circulating Tumor Cells Undergoing the Epithelial–Mesenchymal Transition and Is Associated with Colorectal Cancer Prognosis
Authors: Yokobori Takehiko , Iinuma Hisae , Shimamura Teppei , Imoto Seiya , Sugimachi Keishi , Ishii Hideshi , Iwatsuki Masaaki , Ota Daisuke , Ohkuma Masahisa , Iwaya Takeshi , Nishida Naohiro , Kogo Ryunosuke , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Toh Hiroyuki , Sato Tetsuya , Barnard Graham F. , Fukagawa Takeo , Yamamoto Seiichiro , Nakanishi Hayao , Sasaki Shin , Miyano Satoru , Watanabe Toshiaki , Kuwano Hiroyuki , Mimori Koshi , Pantel Klaus , Mori Masaki
Published: March 2023

Supplementary Figure Legends PDF file - 49K, Legend for Supplementary Figures S1-S9
Supplementary Figure Legends 1-2 from Natural Product Triptolide Mediates Cancer Cell Death by Triggering CDK7-Dependent Degradation of RNA Polymerase II
Authors: Manzo Stefano Giustino , Zhou Zhao-Li , Wang Ying-Qing , Marinello Jessica , He Jin-Xue , Li Yuan-Chao , Ding Jian , Capranico Giovanni , Miao Ze-Hong
Published: March 2023

PDF file - 63K