bluuebunny/crossref_metadata_2025 huggingface dataset:
Human Papillomavirus Infection in Penile Pathologies (Systematic Literature Review)
Authors: Гаптулбарова Ксения Андреевна , Ибрагимова Марина Константиновна , Литвяков Николай Васильевич
Published: November 2023

Введение. Этиология рака полового члена (РПЧ) является многофакторной, в частности, интересным вопросом является ассоциация инфицирования вирусом папилломы человека (ВПЧ) с риском развития рака полового члена. Имеющиеся в литературе результаты по выявлению ВПЧ при новообразованиях полового члена очень противоречивы по сравнению с аналогичными при других ВПЧ-ассоциированных онкопатологиях.
Цель исследования. Систематизация имеющихся мировых литературных данных относительно связи наличия ВПЧ-инфекции с риском возникновения рака полового члена.
Материалы и методы. Поиск проводился с помощью баз данных Pubmed, NCBI и поискового сервиса Google scholar. В результате литературного поиска первично было получено 205 статей по изучаемой тематике, опубликованных с 1991 по 2020 гг. В окончательный анализ вошли 9 исследований, соответствующие абсолютно всем заданным параметрам.
Результаты. Показано, что ВПЧ определяется почти в равной степени как при доброкачественных образованиях и предраковых поражениях полового члена, так и среди образцов нормальной ткани полового члена (контрольных групп). В то время как имеется значительное отличие в количестве ВПЧ-положительных пациентов среди больных с диагнозом рак полового члена и контрольной группой, OR = 142,6. Также определено, что самыми распространёнными генотипами ВПЧ высокого канцерогенного риска (ВКР) оказались 16 и 18.
Заключение. Результаты систематического обзора подтвердили высокую степень риска возникновения РПЧ при наличии ВПЧ инфекции, а также высокий уровень инфицированности ВПЧ при РПЧ (62,0 %).
Semi-Quantitative Analysis of Mirna-21 in Saliva and Blood Plasma as a Non-Invasive Method for Diagnosing Colorectal Cancer, Lung Cancer and Glial Tumors
Authors: Киселева Елена Владимировна , Нефедьев Федор Сергеевич , Захаренко Александр Анатольевич , Зарайский Михаил Игоревич , Селиверстов Роман Юрьевич
Published: November 2023

Малые некодирующие белок РНК (микроРНК), включая микроРНК-21, в последние годы являются предметом изучения как потенциальные малоинвазивные ранние онкомаркеры.
Цель. Оценить уровни экспрессии микроРНК-21 в слюне и плазме крови как метода диагностики колоректального рака (КРР), рака легкого (РЛ) и глиальных церебральных опухолей (ГЦО).
Материалы и методы. Уровни экспрессии микроРНК-21 в плазме крови (ПМР-21) и слюне (СМР-21) пациентов с КРР (n = 65), РЛ (n = 14), ГЦО (n = 21) и 66 здоровых добровольцев (КГ) измерены методом полимеразной цепной реакции обратной транскрипции (ОТ-ПЦР) и выражены в условных единицах (УЕ). Для выявления предикторов КРР, РЛ, ГЦО применяли однофакторный анализ. Для формирования рисковых классов наличия онкологического процесса использовали логистическую регрессию.
Результаты. СМР-21 (УЕ) при КРР (9,67 ± 18,52), ГЦО (2,51 ± 2,39), РЛ (12,27 ± 14,78) и КГ (1,30 ± 2,45) и ПМР-21 (УЕ) при КРР (3,71 ± 7,38), ГЦО (2,17 ± 2,05), РЛ (8,69 ± 6,76) и КГ (0,84 ± 0,64) статистически значимо (р < 0,001) отличались между собой. СМР-21, но не ПМР-21, при КРР с небольшой глубиной инвазии опухоли (T in situ, T2) был выше, чем при Т4 (р = 0,004; р = 0,042). Этого не наблюдалось у больных с РЛ (СМР-21: р = 0,36; ПМР-21: р = 0,6). Предикторами наличия КРР были возраст > 61 года, СМР-21 ≥ 2,0 УЕ или ПМР-21 ≥ 1,6 УЕ (чувствительность и специфичность — 52 % и 89 %, 61 % и 83 % соответственно). Предикторами для РЛ были: возраст ≥ 54 лет, ПМР-21 ≥ 3,5 УЕ или СМР-21 ≥ 2,5 УЕ (чувствительность и специфичность — 78 % и 64 %, 100 % и 86 % соответственно). У больных ГЦО предикторами были: ПМР-21 ≥ 1,5 УЕ или СМР-21 ≥ 1,6 УЕ (чувствительность и специфичность — 57 % и 71 %, 88 % и 77 % соответственно). Регрессионный анализ прогнозирования наличия онкологического процесса на основе СМР-21 хорошо показал себя при КРР (AuROC = 0,79), в отличии от РЛ (AuROC = 0,70) и ГЦО (AuROC = 0,55).
Заключение. СМР-21 является перспективным для диагностики онкологических заболеваний и может быть применен как новый неинвазивный тест при КРР, включая ранние его стадии, и при солидных опухолях других локализаций.
Pembuatan Peta Sebaran Destinasi Wisata di Desa Wisata Angsana, Desa Setu, kecamatan Jasinga.
Authors: Hermawan Helmi Yardi , Viotano Eric , Zalukhu Kristoforus Samorudu , Setiawan Budi
Published: November 2023

Desa Setu, Kecamatan Jasinga mempunyai program kerja jangka panjang. dimanaprogram ini bertujuan untuk mengembangkan Desa Wisata yang ada di Kecamatan Jasingadengan nama Desa Wisata Angsana. Sebelum melaksanakan program kerja, mahasiswa dalamkegiatan pengabdian kepada masyarakat (Pkm) yang berjumlah 22 orang dibagi menjadi 5program studi di beberapa titik. Pertemuan dengan Pengurus Dewi Angsana beserta Bu Kadespada Tanggal 5 Juli 2023 mengenai perencanaan proker dalam kegiatan pengabdian kepadamasyarakat (Pkm) dari tiap prodi yang akan dilaksanakan kick off tgl 11 Juli 2023. Dari prodiperencanaan wilayah kota sendiri akan membuat sebuah peta denah lokasi desa wisataAngsana dengan tahapan awal melakukan sosialisasi kepada masyarakat untuk mendapatkaninformasi,melakukan survei terhadap lokasi wisata untuk mengetahui titik-titik wisata danmelakukan pemetaan, yang bertujuan untuk mempermudah pariwisata untuk mengetahui lokasidesa wisata Angsana itu sendiri. Dikarenakan desa wisata Angsana ini masih tergolong desawisata perintis maka dari itu masih diperlukan suatu ranah perkenalan seperti memberi tahulokasi desa wisata ini agar dapat membantu menemukan arah jalan atau aksesibel yang mudahuntuk menuju lokasi desa wisata angsana yang berada di desa Setu. Kemudian programselanjutnya dari perencanaan wilayah dan kota akan membuat peta sebaran wisata pada desawisata Angsana agar memberi tahu keunggulan serta membantu para turis atau wisatawanmenemukan lokasi wisata yang tersebar pada desa wisata angsana itu sendiri.
Pelatihan Pembuatan Toko Online melalui Aplikasi Shopee sebagai Solusi Pemasaran Digital di Desa Cikidangbayabang
Authors: Putro Bramantiyo Eko , Nazilah Siti , Ramadhan Fikri Miftah
Published: November 2023

Kriteria Usaha Mikro Kecil dan Menengah (UMKM) dibagi bedasarkan pendapatan yang diperoleh.Pemasaran digital dapat meningkatkan pendapatan suatu usaha melalui berbagai aplikasi salah satunya adalah Shopee. Perekonomian desa Cikidangbayabang cukup berkembang, terbukti dengan banyaknya industri kecil. UMKM desa Cikidangbayabang memiliki permasalahan pemasaran produk karena masih dilakukan secara konvensional sedangkan pemahaman mengenai penggunaan teknologi marketplace masih rendah. Program pengabdian masyarakat berupa pelatihan pembuatan toko online dirasa diperlukan. Pelatihan ini bertujuan meningkatkan pemahaman dan kemampuan dalam melakukan pemasaran digitalmelalui marketplace. Berdasarkan hasil pelaksanaan program diperoleh peningkatan kemampuan dan pemahaman para peserta pelatihan. Hal tersebut dapat dilihat dari mekanisme evaluasi pre test dan post testyang dilakukan dimana kesemua pertanyaan mengalami peningkatan persentase jawaban benar.

The criteria for Micro, Small and Medium Enterprises (MSMEs) are divided based on the income earned. Digital marketing can increase a business's income through various applications, one of which is Shopee. The economy of Cikidangbayabang village is quite developed, as evidenced by the many small industries. MSMEs in Cikidangbayabang village have product marketing problems because they are still carried out conventionally while understanding the use of marketplace technology is still low. A community service program in the form of training to create an online shop is deemed necessary. This training aims to increase understanding and ability in conducting digital marketing through the marketplace. Based on the results of program implementation, an increase in the abilities and understanding of the training participants was obtained. This can be seen from the pre-test and post-test evaluation mechanisms that were carried out where all questions experienced an increase in the percentage of correct answers.
Workshop Pembinaan Keterampilan Anak melalui Sablon Kaos di Lembaga Pemasyarakatan Kelas IIA Anak Pria Tangerang
Authors: Gusnita Chazizah
Published: November 2023

Anak sebagai sumber daya manusia dan merupakan generasi penerus bangsa selayaknya mendapatkan perhatian khusus dari pemerintah, dalam rangka pemenuhan pendidikan untukmewujudkan sumber daya manusia yang berkualitas dan berkarakter. Berkaitan dengan pemenuhan hak mendapatkan pendidikan dan pembinaan anak, diperlukan sarana dan prasarana hukum yang mengantisipasi segala permasalahan yang timbul. Setiap anak mempunyai potensi masing-masing dalam mengembangkan diri. Baik di lingkungan keluarga, sekolah, maupun saat menjadi warga binaan di lapas. Seorang anak yang menjadi warga binaan harus diberikan keterampilan sebagai perbekalan diri ketika ia selesai menjalankan masa hukumannya. Bisa jadi anak itu sendiri sudah menjadi dewasa ketika seelesai menjalankan hukuman. Setiap peyimpangan yang dilakukan masingmasing anak di lapas tentunya berbeda satu sama lain. Jika ada anak yang terkait kasus narkoba, bisa saja anak tersebut memiliki  kemampuan menulis, melukis atau lainnya. Tujuan dari pembinaan yang dilakukan adalah agar narapidana tidak mengulangi lagi perbuatannya dan bisa menemukan kembali kepercayaan dirinya serta dapat diterima menjadi bagian dari anggota masyarakat, begitu juga dengan narapidana anak yang masih memiliki masa depan yang panjang dan sebagai penerus citacitabangsa.

 

Children, as a human resource and the nation's successor generation, should be given special attention by the government in order to complete their education and realise their quality and character human resources. Legal means are required to anticipate any challenges that may occur in the achievement of the right to education and the raising of children. Every youngster has the capacity for self-development. Whether in a family neighbourhood, a school, or as a civilian, a youngster who becomes a civil citizen must be taught self-sufficiency skills after completing his period of jail. It's possible that the youngster was already an adult when he was condemned. Every mistake that each youngster has made in the past is unique to them. If a child is involved in a drug case, he may have writing, sketching, or other talents. The goal of the construction is toensure that the prisoner does not repeat his actions and that he can reclaim his confidence and be recognised as a member of the community, as well as with the juvenile prisoner, who still has a bright future and is a successor to the nation's beliefs.
Hubugan Antara Stres dan Komunikasi Interpersonal Dengan Kecanduan Media Sosial Pada Mahasiswa Angkatan 2021 Universitas Darma Persada Jakarta
Authors: Daffa Badruzzaman  , Tatiyani
Published: November 2023

Banyak selkali hal yang ditawarkan delngan kelmajuan telknologi belrbasis intelrnelt ini melmilikidampak positif, hal ini tidak dapat dipungkiri bahwa ada dampak nelgatif dari adanya intelrnelt.Karelna melmiliki manfaat yang dapat dirasakan selcara langsung, melmbuat pelngguna meldia sosialsulit untuk mellelpaskan atau bahkan melngurangi intelnsitas untuk melnggunakan meldia sosial,selhingga lupa banyak waktu yang dihabiskan karelna telrlalu asik melnggunakan meldia sosial.Tujuan dari penelitian ini adalah untuk mengetahui ada hubungan antara stres dan komunikasiinterpsesonal dengan kecanduan media sosial pada mahasiswa angkatan 2021 Universitas DarmaPersada Jakarta. Penelitian ini merupakan penelitian kuantitatif. Populasi dari jumlah siswaterdaftar sebanyak 150 mahasiswa laki-laki dan perempuan dengan sampel berjumlah 108mahasiswa laki-laki dan perempuan. Pengumpulan data menggunakan skala likert danpengambilan sampel menggunakan simple random sampling. Hasil penelitian menunjukkan bahwaterdapat hubungan dengan arah positif yang signifikan antara Stres dengan Kecanduan MediaSosial sebesar r = 0,047 dengan p = 0,000 dan terdapat hubungan dengan arah positif yangsignifikan antara Komunikasi Interpersonal dengan Kecanduan Media Sosial sebesar r = 0,175dengan p = 0,000 . Selanjutnya, hasil analisis data dengan multivariate correlation menggunakanSPSS 25.0 for windows diperoleh koefisien determinasi R square sebesar 0,53 dan berdasarkanregresi korelasi multivariat diperoleh nilai koefisien korelasi R = 0,229 dan p = 0,000 yang berartiterdapat hubungan antara stres dan komunikasi interpersonal dengan kecanduan media sosial padamahasiswa angkatan 2021 Universitas Darma Persada Jakarta.
મહિસાગર જિલ્લાનું પુરાતાત્વિક સ્થળ: કલેશ્વરી
Authors: નિનામા ડૉ. વિજયકુમાર તેજાભાઈ
Published: November 2023

ગુજરાતમાં ઘણી બઘી જગ્યાઓએ પુરાતાત્વિક સ્થળો આવેલા છે, જે આપણા સમૃદ્ધ વારસાને ઉજાગર કરે છે. ગુજરાતના મહિસાગર જિલ્લાના ખાનપુર તાલુકાના લવાણા ગામમાં કલેશ્વરી નામનું પુરાતાત્વિક સ્થળ આવેલું છે. આ પુરાતાત્વિક સ્થળ કલેશ્વરીનું નામ અહીં આવેલા કલેશ્વરી માતાના મંદિરના નામ પરથી પડ્યું છે. આ સ્થળ ‘કલેશ્વરી નાળ’ અને ‘કલેશ્વરી જંગલ’ તરીકે પણ ઓળખાય છે. આ સ્થળ પરથી પ્રાપ્ત થયેલા સ્મારકોને લીધે ગુજરાત સરકારના પુરાતત્વ ખાતાએ આ સ્થળને ઇ.સ. ૧૯૬૫થી રાજ્ય રક્ષિત સ્મારક સમુહ તરીકે જાહેર કરેલું છે. ગુજરાત સરકારે આ સ્મારક સમુહના વિકાસ માટે રૂ./- ૩૯.૧૨ લાખની અને મહિસાગર જિલ્લા વિકાસ સમિતીએ આ સ્થળનો ‘જિલ્લા પ્રવાસન સ્થળ’માં સમાવેશ કરેલો છે. આ શોધપત્રમાં આ સ્થળ સાથે સાથે જોડાયેલી દંતકથાઓ તેમજ આ સ્મારક સમુહમાં આવેલા સ્મારકો વિશે માહિતી આપવામાં આવેલી છે.
LIBRARY AS A HUB: CHANGING ROLE AND FUNCTIONS OF ARCHITECTURAL LIBRARY
Authors: Mandalia Shishir H. , Vyas Dr. Priyanki , Rana Jaypalsinh
Published: November 2023

The importance of learning is rising in the sphere of knowledge. The beginning of human learning occurs at birth. In the past, books served as the main educational, administrative, and industrial resource. A library is a location that has a sizable book collection. It can therefore be used as a main source of education. But as time goes on, the use of libraries declines due to the development of computers and the internet. Customers only need to perform one search on the internet to find the information they want. Furthermore, geographical distance is removed. It was not necessary for the person to go somewhere in order to get information. This puts the survival of libraries in jeopardy. The goal of the current research is to increase library utilization through the addition of additional resources. I explain how to turn a conventional library into an educational center. A learning hub is an advanced technology learning environment with physical and virtual components that offers formal and informal learning opportunities for students to interact with instructors, classmates, and other subject matter experts. The purpose of redefining and refocusing traditional library responsibilities is to support the expansion of knowledge via research. Ten libraries from architectural colleges provided data for the project, and when the data was analyzed, none of the libraries had redesigned their physical spaces to become hubs for learning.
WOMEN WORK PARTICIPATION IN DOKRA: A CASE STUDY FROM BIKNA, BANKURA, WEST BENGAL
Authors: Sarkar Dr. Sibnath
Published: November 2023

The relationship among women, art, and society is a valuable framework for exploring the changing social circumstances of Indian women artisans. The cultural legacy of women artists and their visual art practices are now being accepted as an intellectual contribution in the world of art. The recognition in the global arena motivates rural women to continue forward. Involving in traditional crafting process is very much beneficial for the socio-economic and holistic development of the women and society as a whole. Present study deals with the women work participation in dokra handicraft at Bikna village of Bankura district, West Bengal, India.
GENDER DISPARITY IN LABOUR FORCE AND WORKFORCE PARTICIPATION- A CASE STUDY OF GANDHIDHAM CITY
Authors: Maheshwari Dr. Jagdish
Published: November 2023

According to UNICEF “Worldwide, nearly 1 in 4 girls between the ages of 15 and 19 are neither employed nor in education or training – compared to 1 in 10 boys.”Based on this, it can be said that gender inequality is also found in Labour force and Workforce participation globally. Gandhidham is the main trading centre of Kachchh and is one of the important contributor of the economic development of Kachchh. Therefore, Gandhidham has been selected as a research area in this study. This study seeks to quantify gender inequality in Labour force and Workforce participation of Gandhidham City.
direito ao esquecimento como preceito fundamental para o direito de personalidade e a prevenção de um dano eterno
Authors: Guimarães João Alexandre Silva Alves
Published: November 2023

O Direito ao Esquecimento surge nos Estados Unidos da América (EUA) dentro do direito penal como a possibilidade das pessoas ter defesa em relação a sua imagem e a sua honra. Com a evolução da tecnologia, e principalmente, dos meios de comunicação, o direito ao esquecimento hoje é reconhecido na Europa para a defesa do usuário da internet frente a necessidade da superexposição das redes sociais. Mesmo o Supremo Tribunal Federal tendo julgamento o direito ao esquecimento como incompatível com a Constituição, o Superior Tribunal de Justiça já reconheceu o esquecimento para a defesa dos direitos de personalidade das pessoas frente aos meios de comunicação e aos motores de busca, seguindo o que já foi decidido nos EUA e na Europa. Com isso, existe uma necessidade de reconhecimento no Brasil do Direito ao Esquecimento para que as pessoas possam ter um meio de defesa da sua imagem, da sua honra e da sua privacidade frente a evolução tecnológica, principalmente dos motores de busca e rede social, além dos meios de comunicação tradicionais quando noticiam informações que não são verídicas em sua totalidade.
Betatron Acceleration of Suprathermal Electrons within a Small-scale Flux Rope in the Solar Wind
Authors: Meng Weiduo , Guo Jianpeng , Lin Haibo , Fu Huishan , Zhou Meng , Zhao Dan , Chen Yan , He Linxia , Wang Xianghan , Wang Zelin
Published: November 2023

A growing body of evidence from observations, theories, and simulations indicates that particles can be effectively accelerated in solar wind regions filled with dynamic small-scale flux ropes (FRs). The main acceleration mechanisms identified in simulations include parallel electric field acceleration, first-order Fermi acceleration, and generalized betatron acceleration in contracting or merging small-scale FRs. However, direct identification of these acceleration mechanisms from in situ measurements remains a challenge. Here we present a distinct event of local betatron acceleration within a contracting small-scale FR in the solar wind, due to a local compression. In this event, the lower-energy halo electrons were effectively accelerated through the betatron mechanism, whereas the higher-energy suprathermal electrons predominated by the superhalo component were almost not energized. The halo electron energization processes via the betatron mechanism are reproduced using an analytical model. Further examination of small-scale FRs in the vicinity of the heliospheric current sheet over the period 1995–2020 indicates that in situ signatures of the betatron acceleration process are essentially elusive.
Spatial Extent of Molecular Gas, Dust, and Stars in Massive Galaxies at z ∼ 2.2–2.5 Determined with ALMA and JWST
Authors: Tadaki Ken-ichi , Kodama Tadayuki , Koyama Yusei , Suzuki Tomoko L. , Mitsuhashi Ikki , Ikeda Ryota
Published: November 2023

We present the results of 0.″6-resolution observations of CO J = 3 − 2 line emission in 10 massive star-forming galaxies at z ∼ 2.2–2.5 with the Atacama Large Millimeter/submillimeter Array (ALMA). We compare the spatial extent of molecular gas with those of dust and stars, traced by the 870 and 4.4 μm continuum emissions, respectively. The average effective radius of the CO emission is 1.75 ± 0.34 kpc, which is about 60% larger than that of the 870 μm emission and is comparable with that of the 4.4 μm emission. Utilizing the best-fit parametric models, we derive the radial gradients of the specific star formation rate (sSFR), gas depletion timescale, and gas-mass fraction within the observed galaxies. We find a more intense star formation activity with a higher sSFR and a shorter depletion timescale in the inner region than in the outer region. The central starburst may be the primary process for massive galaxies to build up a core. Furthermore, the gas-mass fraction is high, independent of the galactocentric radius in the observed galaxies, suggesting that the galaxies have not begun to quench star formation. Given the shorter gas depletion timescale in the center compared to the outer region, quenching is expected to occur in the center first and then propagate outward. We may be witnessing the observed galaxies in the formation phase of a core prior to the forthcoming phase of star formation propagating outward.
Phytochemical compounds and pharmacological activities of Ipomoea batatas L.: An updated review
Authors: Suhendy Hendy , Fidrianny Irda , Insanu Muhamad
Published: November 2023

This article provides an overview of Ipomoea batatas L., the Ipomoea genus. The review covers traditional uses, nutritional value, phytochemical compounds, pharmacological activities, and toxicity studies. Data were collected from scientific databases and search engines. Sweet potatoes are used in various countries for traditional uses such as dietary fiber sources, treating allergies, and providing energy in diabetes mellitus treatment. The primary phytochemical compounds in Ipomoea batatas are phenolic compounds, flavonoids, anthocyanins, and carotenoids. Sweet potato contains several nutritional constituents: vitamin C, protein, fiber, carbohydrates, β-carotene, and minerals. Sweet potato exhibits various pharmacological activities, such as antioxidant, aphrodisiac, anticancer, and anti-inflammatory. The types of phytochemical compounds in each part of the plant are different. Each pharmacological activity and mechanism of action depends on the phytochemical compounds, part and variety of the plant, and extraction solvent. However, further study is required to investigate the chronic toxicity of Ipomoea batatas.
Confidence intervals for the difference between coefficients of variation of zero-inflated gamma distributions
Authors: Guo Hongping , Qian Yuhang , Zhu Yiran , Dai Xinming , Wang Xiao
Published: November 2023

The problem of constructing confidence intervals (CIs) for the difference between coefficients of variation of two zero-inflated gamma distributions was considered. As gamma distribution does not have closed form maximum likelihood estimators, the parameters of gamma distribution have to be estimated numerically. To this end, we proposed here four different generalized confidence intervals (GCIs) based on fiducial inference, Box-Cox transformation, parametric bootstrap and the method of variance of estimates recovery (MOVER). Performances of the four GCIs were evaluated and compared via extensive simulation. The simulation results showed that all four methods returned satisfactory results according to coverage probabilities, even for the setting of small sample sizes.
Xylem Vessels Traits of Oil Palm Roots Influenced by Root Diameter and Soil Hydrological Regime
Authors: Amanatun Nisa  , Triadiati Triadiati , Sulistijorini Sulistijorini , Kotowska Martyna M
Published: November 2023

Oil palm has been widely studied regarding growth and development, water use, productivity, and other economically relevant functions. However, not much is known about the hydraulic conductivity of oil palm root systems and how xylem vessels perform their function to transport water from roots to shoots so far. This information is needed to describe oil palm strategies to maintain water status, especially in oil palms that grow under various soil hydrological regimes. To investigate the root hydraulic performance, we measured mean xylem vessel diameter (D), vessel density (VD), vessel lumen area (Alumen), and potential hydraulic conductivity (Kp) for oil palm root samples in seasonally flooded riparian and well-drained sites at Harapan Jambi Forest. The result showed that D, Alumen, and Kp increased with increasing root diameter at both plantation types. On the contrary, VD significantly decreased with increasing root diameter. Potential hydraulic conductivity (Kp) in riparian sites was smaller than in well-drained sites and significantly different in root diameter >2-5 and >5-10 mm and related to both plantation types. The low potential hydraulic conductivity of root xylem vessels and the narrowing of xylem vessel lumen that occurs in oil palm roots in the seasonally flooded riparian sites were presumed as adaptation mechanisms to maintain water supply from the roots to the shoot in oil palm plants in these sites.
Biomineralization Biotechnology Utilizing Lysinibacillus sphaericus to Improve Mechanical Properties of Mortar
Authors: Syarif Ridwan , Chaerun Siti Khodijah , Wattimena Ridho Kresna
Published: November 2023

Biomineralization has notably enhanced the qualities of cement-based materials, particularly through bacterial-facilitated calcite precipitation via calcium lactate oxidation. However, existing research mainly targets self-healing aspects, with little focus on bio-based mortar properties. Consequently, this study provides a comprehensive examination of the enhancements in dry density, ultrasonic pulse velocity (UPV), and flexural strength, achieved through the application of a novel indigenous bacterial strain (Lysinibacillus sphaericus strain SKC/VA-1) from Indonesia, coupled with the incorporation of calcium lactate pentahydrate as an additive. A total of six mortar samples were prepared to investigate the influence of bacteria on the properties of mortar through biomineralization. The samples included plain mortar (M), mortar mixed with calcium lactate pentahydrate (ML), mortar mixed with a 10% v/v bacterial inoculum (MB1), mortar mixed with calcium lactate pentahydrate and a 10% v/v bacterial inoculum (MLB1), mortar mixed with a 20% v/v bacterial inoculum (MB2), and mortar mixed with calcium lactate pentahydrate and a 20% v/v bacterial inoculum (MLB2). The employment of a distinct bacterial strain for oxidizing calcium lactate represents an innovative aspect of the current study. The presence of organic calcium was found to have no adverse effects on the mortar matrix. Optimal inoculum concentrations of bacteria (10% v/v), in conjunction with calcium lactate pentahydrate, yielded superior mechanical properties. Mineralogical characterization via X-ray diffraction and microstructural analysis through scanning electron microscopy substantiated the incidence of calcite precipitation, which facilitated pore infilling and consequently augmented both the ultrasonic pulse velocity and the flexural strength of the mortar.
The Genetic Variability of Indonesian Local Foxtail Millet Accession Based on Agro-morphological Traits and Early Salinity Tolerance Evaluation Utilizing SiDREB2-based SNAP Marker
Authors: Ratnawati Sri , Jannah Rika Miftakhul , Dewi Yuli Irvana , Rizqullah Ramadaniarto , Suwarno Willy Bayuardi , Ardie Sintho Wahyuning
Published: November 2023

Foxtail millet (Setaria italica L. Beauv.) is a grain-producing crop with high nutritional benefits and adaptability to broad environmental conditions. Indonesian local foxtail millet accessions are valuable genetic resources for crop improvement of the species. This study aims to assess the biodiversity of Indonesian local foxtail millet accessions and estimate their salinity tolerance level utilizing the SiDREB2-based SNAP marker and early evaluation at the seedling stage. Our results showed that eight Indonesian local foxtail millet accessions, namely Toraja, Mauliru-2, Hambapraing, NTB-1, ICERI-5, ICERI-6, Botok-4, and Botok-10, had high variability based on agro-morphological traits. The Hambapraing and Mauliru-2 were the potential accessions with high yield estimates (2.33 ton.ha-1 and 1.93 ton.ha-1) and early harvest time (<110 DAT). ICERI-6 was indicated as a salinity-tolerant genotype based on the SiDREB2-based marker and early salinity evaluation at the seedling stage, while Toraja, Mauliru-2, NTB-1, and Botok-4 were categorized as sensitive genotypes. Germplasm variability and the estimated salinity tolerance level of Indonesian local foxtail millet accessions presented in this study serve as essential information in the foxtail millet breeding for high productivity, early harvest time, and salinity tolerant variety.
Malaria endemicity: A survey of antimalarial herbal products in Ijebu Ode, Nigeria
Authors: Opasola Afolabi , Otto Edet , Ogunyemi Kayode , Salami John
Published: November 2023

Empirical evidence has shown that approximately 80% of the global population uses herbal medicines as primary care, especially in developing nations, particularly Nigeria. Despite this, an estimated 95% of global cases of malaria occur in Africa, with Nigeria accounting for approximately 27%. Therefore, the current study investigated the prevalence of antimalarial herbal medicinal products in Ijebu-Ode for the fight against malaria endemicity. It explored their regulatory registration and active plant components, considering the documented evidence of their use for treating malaria. A cross-sectional study was adopted in the collection of empirical data and analyzed in SPSS (version 23.0), while spatial data were analyzed in ARC-GIS, and the results were graphically presented using pictorial variables. The results revealed the availability of approximately 18 different antimalarial herbal products, of which 72.2% were registered with regulatory agencies. Similarly, the herbal products were shown to contain more than one plant species as their active component (Azadirachta indica (83.3%), Nauclea latifolia (55.6%), and Enantia chlorantia (44.4%), which may be responsible for multiple indications (typhoid (83.3%), yellow fever (38.9%), and cold (33.3%). The results of this study provide valuable insights for developing evidence-based policies to standardize and regulate herbal remedies, particularly for combating malaria and other endemic conditions. These findings have implications for public health and the development of effective strategies to address the challenges posed by malaria in Nigeria and other similar regions.
Advances in the synthesis, characterizations and applications of barium titanate. A review
Authors: Lariski Fatima Musa , Zangina Tasiu , Ndikilar Chifu E. , Mohammed J.
Published: November 2023

Barium titanate (BaTiO3) is a compound that has a structure called perovskite. Synthesis of BaTiO3 can be done by employing separate methods. BaTiO3 has four polymorphs which are cubic, tetragonal, orthorhombic and rhombohedral, depending on the temperature, it has a tetragonal structure at ambient temperature. This paper aims to review different synthesis methods of BaTiO3, these techniques can be used in the process of making ceramics as a molding material and also as an intermediate between thin films of metal oxides in various applications. The characterization techniques mostly used in determining the lattice constant, crystal structure functional group, morphology, elemental compositions and electrical properties, of the nanomaterial, including the various applications of BaTiO3 which includes modern electronic appliances and electrical power systems, the Multilayer Ceramic Capacitors (MLCs), biological, and microwave absorption, due to their piezoelectric and dielectric properties are reviewed.
Levels of heavy metals in water and Nile tilapia fish (Oreochromis niloticus) of Eleyele Lake in Ibadan, Nigeria
Authors: Hammed Abdulazeez M. , Akinterinwa Ayodele , Yussuf Hammed A. , Sanusi Kabir A.
Published: November 2023

Surface waters are susceptible to hazardous pollution which may migrate with devastating health challenges through the food chain to humans. This study evaluates the levels of heavy metals in water and Nile tilapia of Lake Eleyele. The physicochemical properties of water samples were determined using standardized methods, while heavy metals in both water and fish samples were determined using atomic absorption spectrophotometer (AAS). Water pH, electrical conductivity, total dissolved solids, total suspended solids, and dissolved oxygen were within WHO and USEPA limits for potable water. Cu (0.028 – 0.112 mgL-1), Pb (0.002 – 0.009 mgL-1), and Zn (1.46 – 3.79 mgL-1) were below the maximum permissible limits by both WHO and USEPA, while cadmium, chromium, and nickel were not detected in the water samples. Cu (2.56 -3.54 mg/kg), Zn (22.93 – 32.13 mg/kg), and Ni (0.39 – 0.48 mg/kg), are within acceptable levels, while Cd and Cr were also not detected in the fish samples. However, Pb (1.71 – 2.30 mg/kg) was higher in the fish samples than the threshold limit (0.3 mg/kg) by FAO and WHO. In accordance, Pb with bioconcentration factor (BCF: 402) was more highly bio-accumulated in the fishes than Cu (BCF: 54.4) and Ni (BCF: 10.97). The results recommend the river water for utility purposes but raised concerns about the consumption of Nile tilapia fishes in the lake.
Effect of feeding diets containing levels of ginger (Zingiber officinale) on digestibility and nitrogen balance of red Sokoto bucks
Authors: Ibrahim U.M. , Abdu S.B. , Musa A. , Saleh I.
Published: November 2023

The apparent digestibility and nitrogen balance of nutrients in isocaloric and isonitrogenous diets containing 0, 250, 500 and 750 g ginger inclusion levels was studied in a 14-day trial involving twenty (20) red Sokoto bucks (RSB) weighing on the average 17.86 kg. The treatments were replicated five times in a completely randomized design. The animals were individually fed at 4% of their body weight for both the concentrate (1.5% as supplement) and Digitaria smutsii hay (2.5% as basal diet). The trial consisted of 7-day adjustment period followed by a 7-day total collection of faeces and urine. Nutrient digestibility, faecal and urine outputs were recorded. Results indicated a similar dry matter intake across the treatments. Crude protein and crude fiber intakes were significantly (P<0.05) affected by ginger inclusion levels with higher values recorded in the group fed 250 g. Dry matter digestibility significantly (P<0.05) increased with increase in ginger levels. Nitrogen retention was significantly (P<0.05) higher in bucks fed with 750 g ginger. It was therefore concluded that, varying inclusion levels of ginger improved nutrient digestibility and nitrogen retention of RSB. RSB can be fed up to 750 g/100 kg diet ginger.
Effect of methanol root extract of Pausinystalia yohimbe on epididymal sperm cells of Wistar albino rats
Authors: Ojatula Adekunle Orimisan , Aturu Oluwadamilola Tubosun
Published: November 2023

The epididymis is essential for spermatozoa maturation, including the acquisition of progressive motility and fertilizing ability. Without a safe dose regimen treating several related reproductive disorders, the root of P. yohimbe remains one of the many herbs commonly used by traditional herbal medicine practitioners in achieving such roles. The purpose of this study was to examine the effect of herbal extract on sperm parameters and histoarchitexture of epididymal sperm cells in rats. Twenty-five Wistar rats were randomly assigned to one of four treatment groups and one control group. For 28 days, the control group received only 10 mL/kg distilled water, while the treatment groups received 25, 50, 100, and 200 mg/kg b.w of P. yohimbe methanol root extract via oral cannula. On day 29, all animals were anesthetized, and their caudal epididymis was isolated and histologically processed. P. yohimbe root extract increased sperm count and motility, with normal histological indices of the epididymises examined relaying immune-protected sperm cells in normal spermatogenetic sequential maturation and viability, without lesion or architectural degeneration, and was comparable to, but not different from, the control. The current study supports the safety profile of P. yohimbe herbal preparation in doses administered to male Wistar rats, and that it could be used to justify human circumstances, potentially improving human health. However, future research on this plant may attempt to look at higher doses under similar conditions, providing a foundation for further screening and research.
Impact assessment of abattoir wastewater on growth and yield of Solanum lycopersicum L (Tomato)
Authors: Mohammed Jibril Sani , Murtala Mansur Musa , Abdulrahman Yahaya Sadiq , Suraj Abdulmalik , Sunday Eghobor , Abubakar Usman , Mayaki Bashir Mohammed , Limangba Idirisu Jibril , Him Madu Abdulkarim
Published: November 2023

The aim of this research was to determine the effect of abattoir wastewater on the growth and yield of tomato plants. The Physicochemical properties of the wastewater such as colour, odour, PH, Total Dissolved Solid (TDS), temperature, Dissolved Oxygen (DO), Biological Oxygen Demand (BOD) and heavy metals were determined using standard analytical procedure. It was found that most of the physicochemical parameters were within the permissible limit stipulated by the World Health Organization (WHO, 1996). A pot experiment was conducted in the botanical garden of the Federal University Dutse. Tomato seeds obtained from JASCO were sown and transplanted into experimental pots with each of the pots watered with different concentrations of Dutse abattoir wastewater. The abattoir wastewater was prepared in the following concentrations (0ml of DAWW +23kg of soil =0%), (200ml of DAWW +23kg of soil =25%), (400ml of DAWW +23kg of soil =50%), (600ml of DAWW +23kg of soil =75%) and (800ml of DAWW +23kg of soil =100%) while distilled water was used as control, the experiment were carried out in complete randomized design with three replications. Statistical analysis using ANOVA revealed that the plant height, number of leaves, flowers and fruits differed significantly (p<0.05) compared to control. It was found that the growth and yield were concentrations dependent in all the weeks after transplanting. Highest growth and yield were observed in tomato plants treated with 800ml (100%) of abattoir wastewater. Abattoir wastewater from Dutse can be utilized for irrigation at best concentration of 100%.
Automatic plagiarism detection using fuzzy-logic
Authors: Sobowale Adedayo , Esan Adebimpe , Tomilayo Adebiyi , Jooda Bunmi , Bolajoko Adekemi
Published: November 2023

Plagiarism occurs when a researcher copies fellow researcher’s work verbatim without acknowledging the author. This work developed an automatic plagiarism detector using fuzzy logic. The system developed was tested with 4 different text documents and evaluated using portability, efficiency, functionality, ease of use and accuracy metrics. Results show that the developed plagiarism detector is very easy to use with high functionality and accuracy as well as moderate efficiency and portability based on user’s assessment. However, future work can increase the data size for model training and consider machine learning techniques to improve accuracy.
Development and validation of reverse - phase HPLC method for detection of tetracycline residue in fresh milk samples
Authors: Ali Shemau Kabir , Salihu Suleiman , Olaleye Abdul Ademola
Published: November 2023

Dairy products are highly required by humans for growth, development and repairs as they are good sources of essential nutrients. Indiscriminate administration of veterinary drugs for prophylactic and therapeutic purposes could lead to the presence of their residues in dairy products such as milk. Reversed-phase high performance liquid chromatographic method with UV detection was developed and validated for detection of tetracycline in milk from five different samples. Mobile phase consisting of a mixture of deionized water, acetonitrile, monobasic potassium and acetic acid was delivered at a flow rate of 1.0 mL/min. The column used was Agilent ZORBAX ODS 4.6 X 150 mm 5μm.. The eluent was monitored by UV detection at 220 nm. Analysis was performed at 35oC and the total run time was 20 minutes. Analytical parameters such as linearity, accuracy, precision and limit of detection were determined by validation procedure and found to be satisfactory. Calibration curve was linear over the concentration range of 0.01- 0.5 mg/mL with an R2 of 0.9978. The limits of detection and limit of quantification were found to be 0.00023 mg/mL and 0.00110 mg/mL, respectively. The % RSD is found to be 3.62, 0.23 and 0.44 for 0.01, 0.1 and 0.5 mg/mL concentration with percentage recovery of 78.7 – 98.6 %. Generally, the developed method was found to be simple, rapid, precise and accurate for quality control of tetracycline in fresh milk samples.
Prevalence, molecular characterization and risk factors of vancomycin-resistant enterococci: evidence from patients admitted in University of Benin Teaching Hospital, Benin City Nigeria
Authors: Beshiru Abeni , Uwhuba Kate Enoh
Published: November 2023

The aim of this study was to determine the prevalence, antimicrobial susceptibility patterns and associated risk factors of vancomycin-resistant enterococci among patients upon admission. One hundred and seventeen samples from newly admitted patients at University of Benin Teaching Hospital were screened. Ten (8.55%) samples were positive for vancomycin resistant enterococci (VRE) isolates based on chromogenic and molecular screenings. The speciation prevalence revealed that 8/10 (80%) was E. faecalis while 2/10 (20%) was E. faecium. The prevalence based on recent histories of antibiotics usage showed that 8/74 (10.8%) of the patients with histories of antibiotics usage in the last six months appeared positive while 2/43 (4.7%) appeared positive from patients with no histories of antibiotics usage in the last six months. The prevalence based on sample types was 4/31 (12.9%) in stool samples, 2/24(8.3%) in wound swabs and 4/49 (8.2%) in urine samples. Most of the isolates 6/10 (60%) showed the presence of van A gene. The VRE isolates showed total resistance towards vancomycin and ampicillin. The MAR index of the isolates tested in this study ranged from 0.33 – 0.78. The prevalence of virulence factor formation as observed was gelatinase activity 6/10(60%), biofilm formation 8/10 (80%), β-hemolytic activity 7/10 (70%), and DNase activity 3/10 (30%). This study demonstrated the presence of VRE in healthcare settings, which is a great threat to public health. Therefore, the development of proper surveillance policies and antimicrobial sensitization programmes to monitor the use of antibiotics is advised with a view to curtailing its spread.
In vitro assessment of the efficacy of three essential oils of aromatic plants against Magnaporthe oryzae B.C. Couch, a rice blast pathogen in Burkina Faso
Authors: Ouattara Souleymane , Sanane Inoussa , Sérémé Abdoulaye , Kassankogno Abalo Itolou , Sirima Adama , Zougrana Sylvain , Koïta Kadidia , Sawadogo Mahamadou
Published: November 2023

Blast, caused by Magnaporthe oryzae B.C.Couch, is the main fungal disease in the rice fields in Burkina Faso. Three pure essential oils at different concentrations of Cymbopogon schoenanthus, Ocimum americanum and Lippia multiflora, and four of their combinations were tested in vitro to evaluate their inhibition properties on mycelial growth, sporulation, and spore germination of M. oryzae. The contact method and the fumigation method were used for the different tests at doses of 0.05 μl/ml, 0.1 μl/ml, 0.3 μl/ml, 0.6 μl/ml, 0.9 μl/ml, 1.2 μl/ml, 1.5 μl/ml, 1.8 μl/ml, 2.1 μl/ml and 2.4 μl/ml. Two chemical fungicides, mancozeb and azoxystrobin and an absolute control were used in the trials. The results showed that the pure essential oil of L. multiflora and its combination with that of C. schoenanthus presented the most effective minimum doses of inhibition in the contact and fumigation method. These doses ranged from 0.1 μl/ml to 0.3 μl/ml for 100% inhibition of radial growth, sporulation, and spore germination of Magnaporthe oryzae. Mancozeb inhibited 100% of all parameters evaluated, while azoxystrobin was ineffective. The essential oil of L. multiflora and its combination with that of C. schoenanthus can be tested in a real environment to control rice blast.
Cytochrome P450 2B6 6 distribution among patients living with HIV in Burkina Faso
Authors: Karfo Raoul , Soudre Fabienne Marie , Kiba Alice , Kouraogo Arnaud , Kabre Elie , Sakande Jean
Published: November 2023

The function of cytochrome P450 (CYP) enzymes, one of the major catalysts in drug metabolism, is significantly influenced by genetic polymorphisms leading to substantial inter-individual variability in drug response and/ or adverse reactions activity. The aim of this study was to determine the frequency of the CYP2B6 516G>T allele in patients living with HIV receiving treatment at the Medical Center of Camp General Aboubacar Sangoule Lamizana for whom the treatment was changed after the initiation of treatment because of the appearance of side effects. 155 HIV-positive patients were enrolled. Genomic Deoxyribonucleic acid (DNA) extraction from blood was performed using the GenJET® Genomic DNA according to the manufacturer’s instructions. Genotyping for the cytochrome P450 variant alleles was performed using predesigned primers. The amplification was carried out by Polymerase Chain Reaction (PCR), while the differentiation between the alleles was carried out after digestion with restriction enzymes by electrophoresis. The results obtained showed. Among these patients, 61 changed treatments during their follow-up. The majority of the 61 patients, 32 patients, received an initial treatment regimen based on the AZT (3'-Azido-3'-Deoxythymidine)/3TC (Lamivudine)/ NVP(Nevirapine) combination, followed by 18 patients for the TDF (tenofovir)/3TC (lamivudine)/ EFV(Efavirenz) regimens. Currently, the majority of patients, 48 patients, have benefited from a therapeutic regimen based on the TDF (tenofovir)/3TC (lamivudine) /DTG(Dolutegravir) combination, followed by 11 patients for the TDF (tenofovir)/3TC (lamivudine)/EFV(Efavirenz) regimens. The distribution of the major allele CYP2B6*T was 68%, and the minor CYP2B6*G allele was 32%. Heterozygote (GT genotype) and Homozygous mutants (TT genotype) and Heterozygote were 31% and 52,5%. Studies could be continued to set up cytochrome mutation detection kits to anticipate the onset of side effects and adapt treatments.