bluuebunny/crossref_metadata_2025 huggingface dataset:
Screening for antifolate and artemisinin resistance in Plasmodium falciparum dried-blood spots from three hospitals of Eritrea
Authors: Mukhongo Harriet Natabona , Kinyua Johnson Kang'ethe , Weldemichael Yishak Gebrekidan , Kasili Remmy Wekesa
Published: June 2024

Background Antimalarial drug resistance is a major challenge hampering malaria control and elimination. About three-quarters of Eritrea’s population resides in the malaria-endemic western lowlands of the country. Plasmodium falciparum, the leading causative parasite species, has developed resistance to basically all antimalarials. Continued surveillance of drug resistance using genetic markers provides important molecular data for treatment policies which complements clinical studies, and strengthens control efforts. This study sought to genotype point mutations associated with P. falciparum resistance to sulfadoxine-pyrimethamine and artemisinin, in dried-blood spots from three hospitals in the western lowlands of Eritrea. Methods Dried-blood spot samples were collected from patients visiting Adi Quala, Keren and Gash Barka Hospitals, between July and October, 2014. The patients were followed up after treatment with first line artesunate-amodiaquine, and dried-blood spots were collected on day three after treatment. Nested polymerase chain reaction and Sanger sequencing techniques were employed to genotype point mutations in the Pfdhfr (PF3D7_0417200), Pfdhps (PF3D7_0810800) and PfK13 (PF3D7_1343700) partial gene regions. Results Sequence data analyses of PCR-positive isolates found wild-type artemisinin haplotypes associated with resistance (Y493Y, R539R, I543I) in three isolates, whereas four mutant antifolate haplotypes associated with resistance were observed in six isolates. These included the triple-mutant Pfdhfr (S108N, C59R, N51I) haplotype, the double-mutant Pfdhfr (N51I, S108N) haplotype, the single-mutant Pfdhfr (K540E) haplotype, and the mixed-mutant Pfdhfr-Pfdhps (S108N, N51I + K540E) haplotype. Other findings observed were, a rare non-synonymous Pfdhfr V45A mutation in four isolates, and a synonymous Pfdhps R449R in one isolate. Conclusions The mutant antifolate haplotypes observed indicate a likely existence of full SP resistance. Further studies can be carried out to estimate the prevalence of SP resistance. The wild-type artemisinin haplotypes observed suggest artemisinin is still an effective treatment. Continuous monitoring of point mutations associated with delayed parasite clearance in ART clinical studies is recommended.
Development and evaluation of parallel simulated annealing algorithm for reactor core optimization problems
Authors: Mikouchi-Lopez Jake , Delipei Gregory , Hou Jason
Published: June 2024

Background The optimization of core loading patterns in nuclear reactors is one of the most studied optimization problems in nuclear engineering due to the enormous economical and safety benefits. Various algorithms such as Genetic Algorithms (GA), Simulated Annealing (SA), and Parallel Simulated Annealing (PSA) have been used in the past for such problems. Methods In this work, a PSA algorithm was developed and integrated into the Modularly Implemented Design Assistance Suite (MIDAS), a framework developed at North Carolina State University to solve nuclear engineering problems. The effectiveness of PSA was compared against the GA and SA algorithms available in MIDAS for a Pressurized Water Reactor first cycle core loading pattern optimization problem. Results PSA consistently generates more optimal solutions than SA and GA by having the higher average fitness, and showing less variance in its performance and thus being more robust. This provides confidence in the PSA implementation within MIDAS. The obtained loading pattern positions high reactive fuel in peripheral locations and low reactive fuel towards the centers in a strategy resembling both Out-In-Checkboard and L3P loading pattern approaches. Conclusions Future studies will involve applying the PSA algorithm to other optimization studies in larger combinatorial spaces, such as in multi-cycle optimization problems.
Acoustic correlates of primary word stress in Estonian
Authors: Sahkai Heete , Mihkla Meelis
Published: June 2024

This study investigates the acoustic correlates of primary word stress in Estonian. The results contribute to several open questions concerning the acoustic correlates of word stress: Does fixed word stress have acoustic correlates? Can duration be the primary acoustic correlate of word stress in a language with contrastive segment length? Is F0 an exclusive correlate of phrase stress or does it also correlate with word stress? The study finds that despite being fixed, Estonian word stress significantly correlates with acoustic features. The primary correlate is F0, followed by vowel quality, overall intensity, duration and spectral tilt. The results support the functional load hypothesis which predicts that duration is not the primary acoustic correlate of word stress in languages with contrastive segment length. The results do not support the assumption that F0 exclusively correlates with phrasal stress and intonational pitch accents.

Kokkuvõte. Heete Sahkai, Meelis Mihkla: Eesti keele primaarse sõnarõhu akustilised korrelaadid. Artiklis tutvustatakse uurimust, mille eesmärk oli tuvastada eesti keele primaarse sõnarõhu akustilised korrelaadid sõltumatult vältest ja lauserõhust. Uurimuse tulemused täiendavad arutelu mitme lahtise küsimuse üle sõnarõhu akustiliste korrelaatide valdkonnas: kas ka fikseeritud sõnarõhul on akustilised korrelaadid? kas kestus saab olla sõnarõhu primaarne korrelaat keeles, kus on kontrastiivne häälikupikkus? kas põhitoon korreleerub ainult lauserõhu või ka sõnarõhuga? Uurimuses leitakse, et kuigi eesti keeles on fikseeritud esisilbirõhk, korreleerub see oluliselt akustiliste tunnustega. Sõnarõhu tugevaim korrelaat on põhitoon, millele järgnevad vokaalikvaliteet, üldintensiivsus, kestus ja spektri kalle. Tulemused toetavad funktsionaalse koormuse hüpoteesi, mille kohaselt kestus ei ole peamine sõnarõhu korrelaat kontrastiivse häälikupikkusega keeltes. Tulemused ei toeta aga eeldust, et põhitoon korreleerub ainult lauserõhu ja tooniaktsentidega.
Św. Jan Ewangelista oraz Madonna Bolesna w zbiorach Muzeum Okręgowego w Toruniu. Rozpoznanie obiektów oraz uwagi o proweniencji
Authors: Rydelska Lena
Published: June 2024

W artykule omówiono problematykę proweniencyjną oraz zagadnienie autentyczności rzeźb przedstawiających św. Jana Ewangelistę oraz Madonnę Bolesną ze zbiorów Muzeum Okręgowego w Toruniu. Badania przeprowadzono w latach 2021–2023. W pierwszej części artykułu został zweryfikowany stan badań, pozwalający na wyłonienie kilku najważniejszych zagadnień problemowych. W tekście umieszczono analizę formalną obiektów, a także ich przemian konserwatorskich na podstawie badań in situ, dokumentacji konserwatorskich i zdjęć archiwalnych, popartych analizą badań, m.in. zdjęć wykonanych w świetle wzbudzanym światłem ultrafioletowym i podczerwonym, oraz badaniem składu pierwiastkowego polichromii. Przeprowadzone badania pozwoliły na podważenie tezy o pochodzeniu obiektów z kościoła pw. Przemienienia Pańskiego w Iławie. Ponadto po przeprowadzeniu analizy formalnej rzeźby te wydają się od siebie zasadniczo odmienne.
El arte como resistencia a lo inaudito: sobre fragmentos de Doris Salcedo y duelos de Clemencia Echeverri
Authors: Acosta López María del Rosario
Published: June 2024

Lo que sigue es una versión ampliada y trabajada del texto que leí como ocasión de la Cátedra Anual Ernesto Restrepo Tirado, organizada por el Museo Nacional de Colombia en noviembre de 2018, y dedicada a la inauguración de Fragmentos, el contramonumento diseñado por la artista Doris Salcedo como el primero de los tres monumentos pactados en La Habana como parte del Acuerdo de Paz entre la guerrilla de las farc (Fuerzas Armadas Revolucionarias de Colombia) y el gobierno de Colombia.1 En el artículo 3.1.7 del acuerdo se estipula la construcción de tres monumentos, uno en Colombia, otro en Nueva York (Estados Unidos) en la sede de las Naciones Unidas y otro en Cuba, que serán elaborados con las armas entregadas por las farc en ceremonia vigilada por las Naciones Unidas en junio de 2017 al gobierno nacional.2 En el transcurso del texto explicaré con detalle las decisiones que atravesaron el proceso artístico de Salcedo y las implicaciones tanto estéticas como políticas que se derivan de su decisión de fundir las armas para la construcción del monumento. Antes de continuar, sin embargo, me gustaría hacer una serie de aclaraciones que se refieren específicamente al momento histórico y coyuntural en el que este texto fue escrito y presentado por primera vez.
Mapping Ethnomathematical Research Directions and Trends in the Scopus Database: A Bibliometric Analysis
Authors: Turmuzi Muhammad , Suharta I Gusti Putu , Astawa I Wayan Puja , Suparta I Nengah
Published: June 2024

Although research on ethnomathematics has been widely carried out, there is still little empirical evidence reporting the mapping and trends of ethnomathematical research in Scopus-indexed journals. The purpose of writing this article is to map trends in ethnomathematical research in Scopus-indexed journals in the range from 1986 to 2022. The fundamental tenet of ethnomathematics is to study, appreciate, and exclusively take into account the application of mathematics by ethnic groups. In other words, in understanding mathematics to look attractive, it is necessary to make a connection between everyday life and the realm of abstract mathematics. Scopus is a resource for further research, identifying scientific uniqueness and gaps. This study uses bibliometric analysis methods using VOSviewer, article searches using Publish or Perish (version 8), and SEforRA applications. Bibliometric research provides a reliable and impartial way to gauge the contribution of an article to knowledge advancement and is a tool that is often used to analyze trends and performance on certain subjects. These findings reveal an increasing trend in ethnomathematical research and identify some topics or keywords that could form the basis for additional studies. In conclusion, for future studies, bibliometric analysis will provide information and knowledge about the evolution of ethnomathematical research.
Double plating is a suitable option for periprosthetic distal femur fracture compared to single plate fixation and distal femoral arthroplasty
Authors: Kriechling Philipp , Bowley Abigail L. W. , Ross Lauren A. , Moran Matthew , Scott Chloe E. H.
Published: June 2024

Aims

The purpose of this study was to compare reoperation and revision rates of double plating (DP), single plating using a lateral locking plate (SP), or distal femoral arthroplasty (DFA) for the treatment of periprosthetic distal femur fractures (PDFFs).

Methods

All patients with PDFF primarily treated with DP, SP, or DFA between 2008 and 2022 at a university teaching hospital were included in this retrospective cohort study. The primary outcome was revision surgery for failure following DP, SP, or DFA. Secondary outcome measures included any reoperation, length of hospital stay, and mortality. All basic demographic and relevant implant and injury details were collected. Radiological analysis included fracture classification and evaluation of metaphyseal and medial comminution.

Results

A total of 111 PDFFs (111 patients, median age 82 years (interquartile range (IQR) 75 to 88), 86% female) with 32 (29%) Su classification 1, 37 (34%) Su 2, and 40 (37%) Su 3 fractures were included. The median follow-up was 2.5 years (IQR 1.2 to 5.0). DP, SP, and DFA were used in 15, 66, and 30 patients, respectively. Compared to SP, patients treated with DP were more likely to have metaphyseal comminution (47% vs 14%; p = 0.009), to be low fractures (47% vs 11%; p = 0.009), and to be anatomically reduced (100% vs 71%; p = 0.030). Patients selected for DFA displayed comparable amounts of medial/metaphyseal comminution as those who underwent DP. At a minimum follow-up of two years, revision surgery for failure was performed in 11 (9.9%) cases at a median of five months (IQR 2 to 9): 0 DP patients (0%), 9 SP (14%), and 2 DFA (6.7%) (p = 0.249).

Conclusion

Using a strategy of DP fixation in fractures, where the fracture was low but there was enough distal bone to accommodate locking screws, and where there is metaphyseal comminution, resulted in equivalent survival free from revision or reoperation compared to DFA and SP fixation.

Cite this article: Bone Jt Open 2024;5(6):489–498.
Gender assignment is local: On the relation between grammatical gender and inalienable possession
Authors: Adamson Luke James
Published: June 2024

Abstract: The grammatical gender of a noun can be sensitive to a number of different factors, including the noun’s lexical semantics, nominalizing morphology, or arbitrary requirements imposed by particular roots (e.g. Corbett 1991, Kramer 2020), though the limits on possible factors are not currently understood, with some work proposing that a noun’s gender can even be valued ‘at a distance’ via agreement with other nominals. The current study explores the understudied phenomenon of gender-possession interactions (Evans 1994), investigating whether being possessed, or being possessable, can have an impact on which gender a noun is assigned. Evidence is provided from four unrelated languages supporting the existence of such interactions. Strikingly, however, these interactions are restricted to inalienable possession; no such interactions have been identified for alienable possession. I propose that this falls out from a general gender locality hypothesis (GLH), which restricts the domain of gender assignment within a phrase n P. The GLH captures the gender asymmetry between ‘local’, inalienable possessors introduced within n P and ‘nonlocal’, alienable possessors introduced outside of n P, for example, in a phrase PossP (Alexiadou 2003, Myler 2016). The GLH also makes further predictions for other features with respect to what may or may not factor into gender assignment, severely restricting or outright prohibiting gender-assignment effects from number, definiteness, and case. Broadly, the work expands our understanding of which types of elements can be relevant to gender assignment and sheds light on underexplored gender-, possession-, and agreement-related phenomena.
Geographical, sex, and socioeconomic differences in non-communicable disease indicators: A cross-sectional survey in Eastern Uganda
Authors: Kibria Gulam Muhammed Al , Meghani Ankita , Ssemagabo Charles , Wosu Adaeze , Nareeba Tryphena , Gyezaho Collins , Galiwango Edward , Nanyonga Judith Kaija , Pariyo George W. , Kajungu Dan , Rutebemberwa Elizeus , Gibson Dustin G.
Published: June 2024

The prevalence of non-communicable diseases (NCDs) is increasing in many low- and middle-income countries (LMICs). This study examined differences in the burden of NCDs and their risk factors according to geographic, sex, and sociodemographic characteristics in a rural and peri-urban community in Eastern Uganda. We compared the prevalence by sex, location, wealth, and education. Unadjusted and adjusted prevalence ratios (PR) were reported. Indicators related to tobacco use, alcohol use, salt consumption, fruit/vegetable consumption, physical activity, body weight, and blood pressure were assessed. Among 3220 people (53.3% males, mean age: 35.3 years), the prevalence of NCD burden differed by sex. Men had significantly higher tobacco (e.g., current smoking: 7.6% vs. 0.7%, adjusted PR (APR): 12.8, 95% CI: 7.4–22.3), alcohol use (e.g., current drinker: 11.1% vs. 4.6%, APR: 13.4, 95% CI: 7.9–22.7), and eat processed food high in salt (13.4% vs. 7.1, APR: 1.8, 95% CI: 1.8, 95% CI: 1.4–2.4) than women; however, the prevalence of overweight (23.1% vs 30.7%, APR: 0.7, 95% CI: 0.6–0.9) and obesity (4.1% vs 14.7%, APR: 0.3, 95% CI: 0.2–0.3) was lower among men than women. Comparing locations, peri-urban residents had a higher prevalence of current alcohol drinking, heavy episodic drinking, always/often adding salt while cooking, always eating processed foods high in salt, poor physical activity, obesity, prehypertension, and hypertension than rural residents (p<0.5). When comparing respondents by wealth and education, we found people who have higher wealth or education had a higher prevalence of always/often adding salt while cooking, poor physical activity, and obesity. Although the findings were inconsistent, we observed significant sociodemographic and socioeconomic differences in the burden of many NCDs, including differences in the distributions of behavioral risk factors. Considering the high burden of many risk factors, we recommend appropriate prevention programs and policies to reduce these risk factors’ burden and future negative consequences.
Intimacy and sexual functioning after cancer: The intersection with psychological flexibility
Authors: Proctor Cecile J. , Reiman Anthony J. , Brunelle Caroline , Best Lisa A.
Published: June 2024

Cancer significantly impacts overall satisfaction with life (SWL). Psychological flexibility (PF) involves adapting to situational demands, balancing life demands, and committing to value-aligned behaviours, which can help survivors manage cancer-related distress. Given the lack of research examining how PF affects relationship and sexual satisfaction, our purpose was to elucidate the relationship between variables associated with partner intimacy, pillars of PF, and variables related to psychological wellness. We explored relationships between SWL and the pillars of PF (Valued Action, Behavioural Awareness, Openness to Experience) as mediating factors in the association between relationship and sexual satisfaction and SWL. Participants (113 male, 106 female) completed questionnaires measuring sexual function, intimacy, relationship and sexual satisfaction, PF, SWL, anxiety, and depression. Results indicated an equal percentage (57.5%) of males and females reported sexual dysfunction; however, varied patterns of relationships emerged between the sexes. There were significant relationships between SWL and relationship and sexual satisfaction. The mediation analyses showed that valued action and openness to experience partially mediated the relationship between relationship satisfaction and SWL. Interestingly, Valued Action was the only pillar of PF that emerged as a partial mediator between sexual satisfaction and SWL. Thus, value-aligned behaviours may be a key focus for intervention in cancer survivors.
Antihypertensive use insights and experiences among hypertensive patients at Korle-Bu teaching hospital
Authors: Oti-Boadi Ezekiel , Osei Evans Appiah , Asare Benedicta , Ampong Sarah , Asiedu Priscilla Ofosuhemaa , Hakami Fateimah A. , Akurugu Paul
Published: June 2024

Background

Across the globe, a vast number of people, amounting to 1.28 billion adults aged 30–79 years, suffer from hypertension. Two-thirds of them reside in low- and middle-income countries, and a significant 46% of these adults with hypertension are unaware of their condition. Hence the study aims to determine the Antihypertensive use insights and experiences among hypertensive patients at Korle-Bu Teaching Hospital.

Methods

A qualitative exploratory design was employed to recruit thirty 30 hypertensive patients from both male and female medical wards as well as the hypertensive clinic at the OPD of Korle Bu Teaching Hospital. The patients were selected using a purposive sampling technique, following which they were involved in face-face in-depth interviews which were audiotaped. Recorded data was then transcribed and analyzed with content analysis.

Findings

The analysis of the data resulted in three (3) main themes and 10 sub-themes. The study uncovered a general lack of knowledge about antihypertensive medications. This limited understanding resulted in a negative attitude among most patients toward the use of prescribed antihypertensive drugs. When it came to their experiences with antihypertensive medications, patients shared a wide range of experiences.

Conclusion

It was concluded that there is a need to improve the knowledge and attitude of patients as these play pivotal roles in determining adherence levels. Thus, interventions such as the organization of educational programs and awareness creation is recommended to improve adherence level and in turn, decrease the prevalence of hypertensive complications associated with poor management.
The impact of macroeconomic policy uncertainty on micro-enterprise investment efficiency—Empirical evidence from China
Authors: Zhou Bing , Liang Bo , Bie Licheng
Published: June 2024

The impact of macroeconomic policy uncertainty (EPU) on micro-level entities has garnered increasing attention in economic circles. This study examines the influence of EPU on the efficiency of investments made by China’s A-share listed companies between 2016 and 2021. Using a panel fixed effect model for analysis, the research reveals that EPU has a notable adverse effect on the investment efficiency of enterprises. Furthermore, it suggests that advancements in digital finance, strong ESG performance, and enhanced entrepreneurial confidence can mitigate this negative impact effectively. The study also highlights that enterprises with lower valuation, shareholder control, limited audit reputation, and no bank connections are more vulnerable to the impact of EPU on investment efficiency compared to those with higher valuation, manager control, strong audit reputation, and bank connections. Consequently, future efforts should be directed towards enhancing the stability and relevance of economic policies, promoting digital finance, and enhancing corporate governance structures.
Investigating the causal effects of COVID-19 vaccination on the adoption of protective behaviors in Japan: Insights from a fuzzy regression discontinuity design
Authors: Chen Fengming , Nakanishi Hayato , Sekizawa Yoichi , Ochi Sae , So Mirai
Published: June 2024

Background

During the COVID-19 pandemic, concerns emerged that vaccinated individuals might engage less in infection-preventive behaviors, potentially contributing to virus transmission. This study evaluates the causal effects of COVID-19 vaccination on such behaviors within Japan, highlighting the significance of understanding behavioral dynamics in public health strategies.

Methods

Utilizing Japan’s age-based vaccination priority for those born before April 1, 1957, this research employs a regression discontinuity design (RDD) to assess the vaccination’s impact. Data from the fourth round of a longitudinal online survey, conducted from July 20 to 27, 2021, served as the basis for analyzing 14 infection-protective behaviors, including mask usage, handwashing, and avoiding crowds.

Results

A total of 12067 participants completed the survey. The analyzed sample size varied by outcome variable, ranging from 1499 to 5233. The analysis revealed no significant differences in the 14 behaviors examined among fully vaccinated, partially vaccinated, and unvaccinated individuals. This consistency across groups suggests that vaccination status did not significantly alter engagement in protective behaviors during the observation period.

Conclusions

Empirical findings highlight the complexity of behavioral responses following vaccination, indicating that such responses may be influenced by various factors, rather than by vaccination status alone. Additionally, this result underscores the importance of crafting public health policies that account for the intricate interplay between vaccination and behavior. This study contributes to the broader discourse on managing responses to the pandemic and tailoring interventions to sustain or enhance protective health behaviors amid vaccination rollouts.
Witches in Swamps, Sirens at Sea, and Leviathans of the Deep: Feminist Figures that Haunt our Social Media Worlds
Authors: Wiens Brianna I. , MacDonald Shana
Published: June 2024

This article considers the resurgence of the monstrous feminine in digital culture, focusing on the memetic manifestation of witches, sirens, and leviathans. We trace the histories of these figures in the digital present, dwelling with their legacies to map and document the feminist resistance that has emerged in response to the neoliberal, misogynist culture of digital space that seeks to stamp out transgression. These media ecologies of the internet thrive on the networked misogyny, white supremacy, and polarization of their systems, brought in by the tech bros who coded them. From within these conditions, we illustrate how digital witches, sirens, and leviathans fight back, offering resistance that transcends digital bounds. In the face of the misogyny of digital culture at large, we argue that each of these figures linger, haunting as they embody, ground, and serve anti-capitalist feminist resistance.
Arising from the Underground
Authors: Cortés Efrén Cruz , Haughwout Margaretha , Huber Sandra , Mengist Nat
Published: June 2024

The constant drive towards “progress,” a requirement for Western modernity, has left an ever-growing catastrophe in its wake. When we realize that capitalist development will not solve our problems, we face a new promise—that of darkness, ancestors, and ruins. Here, we make connections between speculative histories, witchcraft, and the underground. We go beneath, into the roots of hidden forests, into the swamps, the night. We are a multiplicity, a coven, an ever-expanding network as wide as the dead. Gathered around the witch, we draw together multiple subjects to find camaraderie in the margins of colonization. We enter the web that binds us: signs emerge as guideposts, turning to ciphers and sigils, prophecies of incredible beings—plant allies, future guardians, survivors, and algorithms that revolt. Horizon. Revolution. Sprout. Dawn.
Coca Cola Starlight y Coca Cola Byte u 8-bit: perplejidades por unos sabores oscuros
Authors: Centocchi Claudio
Published: June 2024

Desde 2022, Coca Cola ha lanzado sabores de gaseosas de edición limitada: la primera variante, Starlight, sabe a espacio exterior y la segunda, Byte u 8-bit, a píxeles. La sinestesia desafía a realizar formulaciones que excedan si gusta o disgusta la bebida, impulsa un debate lúdico en las plataformas mediáticas acerca del sabor del espacio, los píxeles.
Este artículo analiza, mediante un herramental semiótico, una muestra de videos de youtubers que toman contacto con estas gaseosas, sin ignorar los comentarios inmediatos de la audiencia. Los comportamientos interpretativos de los exploradores indican el fracaso comunicacional de la movida.
Pesquisa artística em literatura digital: um olhar ex-cêntrico
Authors: Catrópa Andréa
Published: June 2024

Este artigo parte de um olhar prismático, forjado a partir da pesquisa artística, para propor algumas reflexões acerca da literatura digital. O termo define um campo majoritariamente experimental, mesmo com os esforços de sistematização impulsionados pela Electronic Literature Organization (ELO), instituição nascida nos Estados Unidos ao fim da década de 1990 e cujo papel, nos últimos anos, tem sido também o de promover um diálogo com países que não sejam anglófonos. Defendemos que uma perspectiva formada pela pesquisa artística epor um ângulo ”fora do centro” possa, apesar das aparentes dificuldades, mostrar-se adequado para abarcar as incertezas, as mutações e os hibridismos da literatura digital, em busca de pontos de fuga à captura integral de suas criações pela lógica do capitalismo artista.
Do Observatório algo se avista: a literatura digital brasileira participa de uma estética da desprogramação
Authors: Salazar Salgado Luciana
Published: June 2024

Este artigo apresenta o percurso de criação e implantação do Observatório da Literatura Digital Brasileira, um projeto desenvolvido na Universidade Federal de São Carlos no âmbito do Programa de Pós-graduação de Estudos de Literatura, na linha de pesquisa Literatura, linguagens e meios. Tão importante quanto o próprio Observatório, que é pioneiro na compilação da produção brasileira, o processo que permitiu sua implantação parece especialmente interessante para a discussão que nos leva ao que entendemos ser um elemento central da literatura digital brasileira, a saber, o que referimos por “uma estética da desprogramação”, na qual questões técnicas e éticas estão fortemente implicadas.
Anfipoemas e Contrapoemas, de Wlademir Dias-Pino e Regina Pouchain: Séries de Poesia Digital Situada no Brasil
Authors: Carvalho Pereira Vinícius
Published: June 2024

O presente artigo apresenta as séries de poesia visual Anfipoemas e Contrapoemas, elaboradas por Wlademir Dias-Pino e Regina Pouchain de 1995 a 2008, a fim de compreendê-las no campo da literatura digital brasileira. Inicialmente, procedemos a uma descrição das duas séries, em seus elementos verbais, visuais e seriais, bem como suas conexões com outros trabalhos de ambos os artistas. Na sequência, discutimos os anfipoemas e contrapoemas como literatura digital, na medida em que são atravessados pela mídia computacional em termos tanto da produção (por meio do software editor de imagens Adobe Photoshop) quanto da recepção (seja como instalações artísticas mediadas por projetores multimídia, seja em blogs que arquivam parte das séries poéticas). Nesse processo, consideramos ainda a importância de adotar uma concepção de literatura digital situada no Brasil, país na periferia do tecnocapitalismo, a fim de melhor compreender os contextos de produção e recepção dos anfipoemas e contrapoemas.
Effectiveness of Bile Acid Sequestrants in Microscopic Colitis and Utility of Bile Acid Testing: A Systematic Review and Meta-analysis
Authors: Tome June , Tariq Raseen , Chelf Cynthia J. , Khanna Sahil , Pardi Darrell S.
Published: June 2024

INTRODUCTION:

Bile acid sequestrants (BAS) are an option for microscopic colitis (MC) refractory or intolerant to budesonide. There are inconsistent data on the prevalence of bile acid malabsorption (BAM) and utility of bile acid testing in MC. The aim of this systematic review and meta-analysis was to evaluate these outcomes.

METHODS:

A systematic search of randomized control trials and observational studies of adults with MC treated with BAS was conducted using MEDLINE, Embase, Cochrane, and Scopus from inception to January 22, 2024. Data were extracted on (i) prevalence of BAM, (ii) clinical response and adverse events, and (iii) recurrence after BAS discontinuation. Data were pooled using random-effects models to determine weighted pooled estimates and 95% confidence intervals (CIs).

RESULTS:

We included 23 studies (1 randomized control trial, 22 observational), with 1,011 patients with MC assessed for BAM and 771 treated with BAS. The pooled prevalence of BAM was 34% (95% CI 0.26–0.42, I
2 = 81%). The pooled response rate with BAS induction for all patients with MC, irrespective of BAM, was 62% (95% CI 0.55–0.70, I
2 = 71%). There was a higher pooled response rate in patients with BAM compared with those without BAM (P < 0.0001). The pooled rate of BAS-related adverse effects was 9% (95% CI 0.05–0.14, I
2 = 58%).

DISCUSSION:

One-third of patients with MC had BAM, and almost two-thirds of all patients responded to BAS with limited side effects. Patients with MC and BAM were more likely to respond to therapy, supporting the value of bile acid testing.
A TERRITORIALIZAÇÃO DE POLÍTICAS CULTURAIS: UMA ANÁLISE DO PLANEJAMENTO ESTRATÉGICO DO RIO DE JANEIRO PARA O PERÍODO DE 2021 - 2024
Authors: Guimarães Bruno Costa
Published: June 2024

O Plano Estratégico 2021-2024 da cidade do Rio de Janeiro pode ser definido como um conjunto de ações concretas, demarcadas por metas, para pensar a cidade no prazo do mandato em vigência. Com relação às políticas culturais, o plano tinha como meta territorializar o fomento para as zonas norte e oeste, áreas periféricas da cidade. O artigo tem como objetivo discutir como o conceito de território influenciou a implementação das políticas culturais na capital do estado fluminense dentro de seu plano estratégico. Como metodologia, foi realizada uma discussão teórica acerca da relação entre a Geografia e políticas públicas, seguida de uma análise da divisão territorial do Rio de Janeiro dentro do planejamento estratégico para políticas culturais e, por fim, uma leitura crítica da primeira edição do programa de fomento à cultura carioca (FOCA). Como resultado, constatou-se que o programa de fato possui um olhar direcionado para as zonas periféricas, mas que as diferenças internas da zona oeste e o baixo valor da linha territorial do programa urgem a necessidade de um olhar geográfico mais atento aos territórios de planejamento da cidade.
CONTEXTO LITOESTRATIGRÁFICO E CONSIDERACÕES SOBRE A FORMAÇÃO DO JAZIGO FOSSILÍFERO DO MUNICÍPIO DE CRUZEIRO DO OESTE-PR
Authors: Fortes Edison , Lima Rosana Natieli de , Marques Américo José , Volkmer Susana , Roque Daniela Cristina , Mazzoni Vitor Bassi
Published: June 2024

Esse trabalho teve por objetivo a descrição estratigráfica do jazigo fossilífero e a interpretação das condições de deposição, bem como das relações litofaciológicas da sequência sedimentar da Formação Rio Paraná, com destaque para o sítio paleontológico do Município de Cruzeiro do Oeste, no Estado do Paraná. O afloramento estudado é representado por uma sequência rítmica de estratos centimétricos, composto predominantemente por areia fina, formando uma sequência de pelo menos três estratos, intercalados por níveis argilosos milimétricos com hematita, ricos em fósseis de pterossauros. A disposição caótica destes elementos, junto ao topo de cada estrato, indica para a interpretação de uma deposição em condições de transbordamento de águas, com escoamento superficial efêmero distal, e no qual denominamos de Litofácies de Planície de Transbordamento. Essa litofácie grada de forma transicional em direção ao topo para sequência arenosa fina, com estruturas sedimentares tênues, associadas a marcas de ondas na parte basal da camada. Essa sequência foi interpretada como Litofácies de Lençóis de Areia, depositadas inicialmente em condições de maior umidade do substrato e gradando para condições mais secas em direção ao topo.
Recessões gengivais na vestibular de incisivos inferiores: uma lesão com etiopatogenia própria!
Authors: Consolaro Alberto , Cardoso Maurício
Published: June 2024

Introdução: Na região vestibular dos incisivos inferiores, forças ativas decorrentes de contenções ortodônticas se somam às geradas pela interferência oclusal induzida pela movimentação indesejada. Objetivo: Discorrer, teoricamente, sobre as alterações decorrentes, para caracterizar um quadro bem específico dessa região. Métodos: Para tal, usou-se de observações microscópicas de dentes movimentados experimentalmente, associando-as à experiência de casos clínicos que ofereciam dificuldades de diagnóstico clínico e tratamento. Resultados: As recessões podem ser classificadas como lesões periodontais: 1) reversíveis, 2) ainda reversíveis e 3) irreversíveis. Conclusão: As recessões na área vestibular de incisivos inferiores fazem parte da lesão de Trauma Oclusal, que se apresenta de forma muito específica na vestibular dos incisivos inferiores, inclusive quanto às suas causas e mecanismos.
Status Kualitas Perairan Bagian Hulu dan Hilir Sub DAS Gung Sungai Babon Semarang
Authors: Ulfitasari Nia , Purnomo Pujiono Wahyu , Ain Churun
Published: June 2024

Sub DAS Gung merupakan salah satu dari bagian DAS Babon yang memiliki peran yang sangat penting bagi wilayah sekitar hulu Sub DAS yaitu pada Provinsi Jawa Tengah, khususnya wilayah Semarang dan sekitarnya. Selain menerima limbah pertanian dan limbah rumah tangga juga menerima limbah industri besar. Studi mengenai analisis kualitas air merupakan salah satu sarana penting untuk mengetahui kualitas air suatu perairan. Banyak sungai yang mengalami pencemaran saat ini, diantaranya pencemaran karena limbah industri, limbah pertanian, limbah peternakan maupun limbah rumah tangga. Tujuan penelitian ini untuk mengetahui status beban pencemaran dan nilai Indeks Pencemaran (IP) pada bagian Sub Daerah Aliran Sungai (DAS) Gung bagian hulu dan hilir Sungai Babon pada tahun 2021 dan tahun 2022. Penelitian dilakukan di Sungai Babon bagian hulu terdapat di kelurahan Susukan dan hilir di kelurahan Kalikayen, kecamatan Ungaran Timur, Kabupaten Semarang pada musim hujan dan kemarau, tahun 2021 dan 2022. Penelitian ini dilakukan dengan cara mengambil sampel air di bagian hulu dan hilir Sub DAS Babon, Semarang. Setiap sampel akan diamati parameter fisika dan kimia. Komponen Fisika diantaranya TSS, debit dan temperatur. Parameter Kimia yaitu BOD, COD, DO dan pH. Hasil yang didapatkan Beban pencemaran pada tahun 2021 dan 2022 di musim kemarau memiliki nilai beban pencemaran tertinggi pada COD di bagian hilir, Pada tahun 2021 dan 2022 beban pencemaran di musim penghujan memiliki nilai beban pencemaran tertinggi pada COD di bagian hulu. Serta nilai status Indeks Pencemaran (IP) rata rata pada musim penghujan dan musim kemarau ditahun 2021 dan 2022 adalah tergolong tercemar ringan.
WEITER WISSEN. Mit uns! Mit der Kampagne WEITER WISSEN machen wissenschaftliche Bibliotheken ihre Leistungen für eine offene Wissenschaft und Forschung sichtbar
Authors: Bäßler Kristin
Published: June 2024

Wissenschaftliche Bibliotheken im 21. Jahrhundert sind von zentraler Bedeutung für Bildung und Forschung. Sie dienen als Informationsinfrastrukturdienstleister und bieten ein breites Spektrum an Wissensressourcen. 15 große wissenschaftliche Bibliotheken haben sich zusammengetan und gemeinsam mit dem Deutschen Bibliotheksverband die Kommunikationskampagne WEITER WISSEN konzipiert und entwickelt. Das Ziel der Kampagne ist es, die gesellschaftliche Relevanz wissenschaftlicher Bibliotheken, ihre Aufgaben und Funktionen sichtbar zu machen.

Der Beitrag gibt einen Einblick in die Ziele und die Umsetzung der Kampagne WEITER WISSEN und zeigt, wie die wissenschaftlichen Bibliotheken die Kampagne für ihre eigene Öffentlichkeitsarbeit nutzen können. Zugleich zeigt der Artikel anhand des Themas „Forschungsdatengesetz“, wie Bibliotheken und Verbände mit Stellungnahmen und Austauschformaten ihre Interessen gegenüber der Politik vertreten.
Study of weighted elliptic composition operators on the unit ball of ℂ
N
Authors: Oger Lucas
Published: June 2024

We study the general properties, point spectrum and spectrum of a weighted composition operator

W

m
,
φ

{W}_{m,\varphi }

with elliptic symbol

φ

\varphi

on the unit ball

B

N

{{\mathbb{B}}}_{N}

of

C

N

{{\mathbb{C}}}^{N}

, and general weight

m
∈
Hol

(

B

N

)

m\in {\rm{Hol}}\left({{\mathbb{B}}}_{N})

. We give a complete description of the spectra in the majority of cases, and we provide inclusions in general.
Homology of configuration spaces of surfaces modulo an odd prime
Authors: Bianchi Andrea , Stavrou Andreas
Published: June 2024

For a compact orientable surface

Σ

g
,
1

\Sigma_{g,1}

of genus 𝑔 with one boundary component and for an odd prime number 𝑝, we study the homology of the unordered configuration spaces

C
∙

(

Σ

g
,
1

)

:
=

∐

n
≥
0

C
n

(

Σ

g
,
1

)

C_{\bullet}(\Sigma_{g,1}):=\coprod_{n\geq 0}C_{n}(\Sigma_{g,1})

with coefficients in

F
p

\mathbb{F}_{p}

.
We describe

H
∗

⁢

(

C
∙

⁢

(

Σ

g
,
1

)

;

F
p

)

H_{*}(C_{\bullet}(\Sigma_{g,1});\mathbb{F}_{p})

as a bigraded module over the Pontryagin ring

H
∗

⁢

(

C
∙

⁢

(
D
)

;

F
p

)

H_{*}(C_{\bullet}(D);\mathbb{F}_{p})

, where 𝐷 is a disc, and compute in particular the bigraded dimension over

F
p

\mathbb{F}_{p}

.
We also consider the action of the mapping class group

Γ

g
,
1

\Gamma_{g,1}

and prove that the mod-𝑝 Johnson kernel

K

g
,
1

⁢

(
p
)

⊆

Γ

g
,
1

\mathcal{K}_{g,1}(p)\subseteq\Gamma_{g,1}

is the kernel of the action on

H
∗

⁢

(

C
∙

⁢

(

Σ

g
,
1

;

F
p

)

)

H_{*}(C_{\bullet}(\Sigma_{g,1};\mathbb{F}_{p}))

.
Philosophie, Theorie, Leben
Authors: Hampe Michael
Published: June 2024

Contemplative and explanatory theories are distinguished. The corpus of European philosophy includes many sorts of texts. Only a few have explanatory value. Some are contemplative. But there are also therapeutic and sceptical texts. It was an old ideal of philosophy to lead a theoretical life. What could that mean? What does “life” mean in this context? We cannot choose forms of life, because all choices and preferences come up in life. Nevertheless a theoretical life is possible. What kind of life is it – one spent in contemplation, in explanation, or a sceptical one?
Ohne Heimat
Authors: Tränkle Sebastian
Published: June 2024

This essay reconstructs the relationship between critique and theory constitutive for Critical Theory. Based on Max Horkheimer’s 1937 program, the first part shows that “critical behaviour” must, on the one hand, seek proximity to social practice. On the other hand, such behaviour is dependent on the distance from its object that all “theoretical work” entails. Since the inception of a genuinely critical theory in the early works of Karl Marx, the proximity to practice goes hand in hand with the demand to work towards its change, implying a proximity to political movements. The second part shows that, for historical reasons, Horkheimer’s program distances itself from such movements. The third part interprets this dialectical attitude towards social practice as conditioning the peculiar – ideology-critical – capacity of Critical Theory. In conclusion, the fourth part problematises two current tendencies towards dissolving said dialectics: a return to what Horkheimer calls traditional theory on the one hand, and the abandonment of the demanding social-theoretical program in favour of political positioning on the other.
Mechanochemical synthesis of a red luminescent coordination polymer from a polydentate quinoline ligand with large conjugation
Authors: Jia Xueli , Kong Fan
Published: June 2024

A red luminescent coordination polymer has been prepared from a polydentate 8-hydroxyquinoline ligand via mechanochemical synthesis. The obtained coordination polymer is micro/nano spherical and can suspend stably in organic solvents after ultrasonic treatment. Due to the large conjugation of the ligand with a strong polar s-triazine core, the coordination polymer shows a largely red-shifted emission relative to the ligand. The photoluminescence peak of the coordination polymer in organic solvent is at 613 nm, while a largely red-shifted photoluminescence peak at 675 nm and a shoulder peak at 770 nm are found in the photoluminescence spectrum of the coordination polymer in solid due to the strong interchain interaction.
Symptomatic Comedy. On Alenka Zupančič’s The Odd One In and Happiness
Authors: Huzarski Maciej
Published: June 2024

The article investigates a possible omission within Alenka Zupančič conceptualization of comedy as presented in her 2008 book The Odd One In: – on Comedy. The lack which this work will reveal lies in Slovenian philosopher’s neglect of the conditions of possibility of experiencing comedy, which – we claim – hinges upon happiness, a state forged and conditioned by a particular relation with the “other” (the primal object in psychoanalytical meaning). In order to execute such investigation, the methodological tool, rooted in both the theories of comedy and psychoanalysis, will be introduced: the navel of thought. This notion will make use of the reasoning of Sigmund Freud and posit the existence of a symptomatic point within any theory of comedy, that is a point at which a certain incongruence of the theory plays out. It is only when we are equipped with the theoretical tool of the navel of the thought will we proceed to find such a point within Alenka Zupančič book.
La Competencia Ecociudadana del Alumnado de Primaria frente la Pérdida de Biodiversidad
Authors: Rammou Chadia , Martín-Ferrer Laura , Amat Arnau
Published: June 2024

El presente estudio quiere profundizar en el posicionamiento ético y político que constituyen las dimensiones propias de la ecociudadanía defendida por Sauvé del alumnado de primaria frente la pérdida de la biodiversidad que es uno de los retos que la humanidad tendrá que afrontar en los próximos años. Los datos se recopilaron a través de grupos de discusión con alumnado de primaria que participaban en un proyecto educativo sobre la fauna de los patios. Los resultados han permitido comprender el posicionamiento ético delante de la problemática caracterizando las expresiones emocionales manifestadas por el alumnado y por otra parte comprender su posicionamiento político a través de las propuestas de acciones para mejorar la biodiversidad a nivel global y local. El alumnado, vive con tristeza y rabia la pérdida de biodiversidad al percibir el ser humano como principal causante y a la vez como afectado de esta perdida. En paralelo, a lo largo del proyecto educativo vemos un cambio en el tipo de acciones propuestas para la mejora de la biodiversidad sugiriendo más aportaciones colectivas
Recognising, Naming, and Resisting Racialisation and Ethnicisation in Swedish Compulsory Schools
Authors: Lozic Vanja
Published: June 2024

Swedish schools and teachers are responsible for implementing measures that promote social justice. Based on qualitative data from observations, interviews, and student reflections and perspectives on intersectionality, the study critically analyses how students and school staff partake in ethnicised and racialised oppression of Swedish compulsory school students. The interplay between different bodies in school contexts and children’s responsive capacities to resisting oppression is of particular interest. The findings indicate that the oppression and control of body space based on ethnicity and race are often intertwined with various power structures, such as social and economic background, age, religion, and masculinity. Moreover, the majority’s silence plays a crucial role in perpetuating oppression. However, students who experience oppression have the ability to resist the coercive power of their peers and adults. The article proposes that students and school staff should enhance their ability to recognise and identify oppressive power dynamics within their local contexts. By developing these competencies, individuals can reflect on their role in perpetuating oppression, performatively open new possibilities, and learn how to take transformative action and enhance social justice
Atención a Mujeres Mayores Víctimas de Violencia de Género en Centros de Información a Mujeres
Authors: Mosteiro M.ª  Josefa , Barrreiro Felicidad , García Antelo Beatriz , Zamora Elisa Teresa
Published: June 2024

La violencia de género en mujeres mayores de 65 años es un fenómeno invisible y oculto con graves consecuencias para las que sufren este tipo de violencia en silencio, de ahí la necesidad de visibilizar las actuaciones que se están llevando a cabo a nivel institucional para poder dar respuesta a este grave problema social. En este trabajo se lleva a cabo un análisis de la atención prestada a mujeres mayores de 65 años en los servicios de apoyo a las víctimas de violencia de género. Se realizó una investigación de carácter cualitativo, mediante un diseño de estudio de casos, en el que participaron ocho mujeres profesionales que trabajan en Centros de Información a Mujeres de Galicia. A través del uso de la entrevista como técnica de recogida de información se indagó en las medidas específicas de actuación, el proceso de intervención, las barreras y la disponibilidad de protocolos específicos. Los resultados obtenidos ponen en evidencia la necesidad de adaptar los recursos existentes a las características particulares de las mujeres mayores víctimas de violencia de género y de llevar a cabo actuaciones de prevención, formación y sensibilización destinadas expresamente para ellas.