bluuebunny/crossref_metadata_2025 huggingface dataset:
New variety of winter garlic Ashlan for the north of the European part of Russia
Authors: Motov V.M. , Motova M.V. , Seredin T.M. , Bardovskaya A.I.
Published: May 2024

The article presents the results of the work of the laboratory of vegetable crops “Federal Agrarian Research Center of the North-East named after N.V. Rudnitsky” and the breeding nursery of LLC Research and Production Company “Agrosemtoms” on the study of winter garlic new variety Ashlan, which was created for 7 years and zoned in the VolgaVyatka region. It was created for cultivation and use in the domestic market. It is adapted to mechanized planting, with large bulbs and a small number of large cloves, winter-hardy. Garlic is a local crop and its morphobiological features may change depending on the growing conditions, so it is advisable to take into production plastic, local variety Ashlan.
Hemp (cannabis sativa l.) Is an effective carbon-depositing crop
Authors: Ismagilov R.R. , Rusakov I.A.
Published: May 2024

The article presents the results of a quantitative assessment of carbon deposition by sowing hemp (Cannabis sativa L.). Field studies were conducted in Khabibrakhmanov Peasant Farm Enterprise (Republic of Bashkortostan), the carbon content in plant biomass was determined by the CN 802 analyzer. It was found that cannabis crops form 7.87 t/ha aboveground biomass at the end of the growing season, including stems – 6.40 t/ha (81.3% of the aboveground mass), inflorescences – 0.77 t/ha (9.8% of the aboveground mass), seeds - 0.70 t/ha (8.9% of the aboveground mass), and roots - 1.02 t/ha. Of the total biomass, 8.19 t/ha is preserved. Sowing captures a relatively large amount of carbon dioxide from the atmosphere (14.78 t/ha) and, accordingly, carbon (4.03 t/ha). The effectiveness of cannabis in terms of decarbonization mainly consists in the conservation of a significant amount of accumulated carbon (91%) for a long time into long-term products and into the soil. The cultivation of hemp in carbon farms is recommended to reduce the carbon footprint and sell carbon units.
Use of microcapsules of biologically active substances of callus culture of wild and cultivated plants for the production of functional foods
Authors: Kharapaev M.N. , Tikhonov S.L. , Tikhonova N.V.
Published: May 2024

This study is focused on developing an innovation instant porridge incorporated with micro-encapsulated Ocimum basilicum and Eleutherococcus senticosus callus cultures and ascorbic acid. It will be one of the best choices for population as a healthy snack in order to enhance the consumer reachability. Ocimum basilicum and Eleutherococcus senticosus callus cultures and ascorbic acid are microencapsulated using the fluidized-bed method. The optimal parameters for extract drying and microencapsulation were determined: temperature 90℃, aspiration 100 ± 0.8 m3/h, solution supply rate to the installation 8 ± 0.3 ml/min, concentration of protective coating and particles 1:4, droplet size 5-10 µm, duration of microencapsulation is 20 minutes. Recipe for innovative instant porridge (net weight, kg): oat flakes 73.0; semi-finished cheese meat product 27.0; table salt 1.2, chicken flavoring 1.2; microencapsulated ascorbic acid and callus cultures: 0.5; ascorbic acid 0.2; callus culture 0.2; protective coating 0.1; product yield 102.29.
Assessment of the phytotoxicity of petroleum-polluted black soil in relation to agricultural and wild species of phytoremediator plants
Authors: Grigoriadi A.S. , Fedyaev V.V. , Sotnikova Yu.M. , Yamaleeva A.A. , Farkhutdinov R.G.
Published: May 2024

The effect of petroleum pollution on soil was assessed for its impact on the adaptation properties of 12 agricultural and 5 wild plant species. The influence of petroleum on seed germination was determined at concentrations of 1%, 3%, 4%, 6%, and 8% in the soil. Wild plants exhibited lower germination rates compared to cultivated species. For most cultivated plants, a 1% concentration of petroleum did not inhibit seed germination, but germination decreased to 60-80% of the control under concentrations of 2% and 4%. In soil containing 6% petroleum, peas, clover, alfalfa, and sunflower exhibited germination rates of more than 50%, while alfalfa and sunflower germinated only at an 8% concentration. The assessment of soil phytotoxicity revealed that sunflower plants are the most resistant to petroleum pollution. A comparison of resistance to soil petroleum pollution among four sunflower varieties showed that the ’Bombardir’ cultivar exhibited the best growth parameters.
Assessment of aboveground biomass and carbon accumulation in natural cenoses on the terraces of the northern slope of Khoysko‐the
Makazhoy (Cheberloy) basin
Authors: Iriskhanova Z.I. , Bekmurzayeva R.H.
Published: May 2024

Carbon exists as carbon dioxide in the atmosphere and makes up about 0.04% of the atmosphere. In the recent past, it has attracted a lot of attention as a greenhouse gas because it can influence the climate model of the world. Anthropogenic activities such as industrialization, deforestation, forest degradation and the burning of fossil fuels have caused an increase in atmospheric carbon levels and disrupted the global carbon cycle. The Climate Change Expert Group has identified five carbon pools of the terrestrial ecosystem that include biomass, namely aboveground biomass, underground biomass, debris, woody debris and soil organic matter. Among all carbon pools, aboveground biomass constitutes the major part of the carbon pool.
Protection of the mainline territories of the Mountainous Crimea from technogenic physical factors
Authors: Gutnik Sergey A. , Osadchaya Lilia I.
Published: May 2024

The structure of highways, their categories and features of laying, the scheme of high-voltage power lines in the Mountainous Crimea are considered. The assessment of the degree of isolation of forest areas, including specially protected natural areas, is given. The results of the study of the parameters of physical factors in the mainline territories – noise, lighting, electromagnetic field - are presented. The natural conditions and species composition of the animals of the Mountainous Crimea, the influence of the isolation of their habitats are analyzed. Recommendations are given on optimizing safe migration routes for animals across roads in the southwestern part of Crimea, considering the terrain.
The platform ecosystem of the regional agro-industrial complex: The concept of structure and approaches to assessment
Authors: Kivarina Mariya , Yurina Nataliya
Published: May 2024

The modern agro-industrial complex and its branches, in order to fulfill the conditions of the economic and innovative development of the country, must represent high-tech areas of economic activity. Digitalization – the widespread use of information technology – plays a primary role in this process. For agriculture, this direction can be implemented by creating a unified computerized system of the industry, namely, a platform ecosystem of the digital agro-industrial complex. Within the framework of this article, the concepts of the platform economy are considered, the degree of use of digital platforms in organizations by type of economic activity is studied. A comparative analysis of Russian digital platforms used in agriculture has been performed. The concept of the structure of the platform ecosystem of the digital agro-industrial complex, involving the introduction of a regional digital platform, is presented. An algorithm and a methodological approach to assessing the effectiveness of the implementation and functioning of the digital platform of the regional agro-industrial sector are presented.
Systematic approach to providing intelligent decision support whilst digital transformation of management processes in agro-industrial complex
Authors: Bolodurina Irina , Rakhmatullin Rustam , Speshilov Evgenij
Published: May 2024

Modern economic conditions, characterized by digitalization processes and the influence of geopolitical factors contributing to the development of domestic information technologies have made the issue of providing support for management decision-making by specialized systems important. In this regard, the purpose of the study is to analyze the logistics of information flows and identify problems associated with the digital transformation of management processes in the agro-industrial complex (AIC). A systematic approach was chosen as the main method. The logical analysis and synthesis were used as well. Based on the identified movements and interrelations of information flows, and limiting factors for its effective use, an automated information and analytical decision support system (AIASDSS) is proposed in the context of a unified digital platform. Its components are described and principles of operation are formulated. In the focus is the creation of an information platform module oriented mainly on agricultural producers who occupy a central place in the agro-industrial complex. It is noted that work is underway to ensure the intellectualization of decision-making processes in agricultural organizations through the use of mathematical, statistical and information tools. Particular solutions are given. The research materials are addressed to authorities and can be used in managing agricultural production.
Finger-jointed wood compressed parallel to the grain: Experiment and modelling
Authors: Gavrilov Timmo , Kolesnikov Gennady
Published: May 2024

Compression tests of pine specimens of two types with initial dimensions of 40x40x80 mm and 40x40x80 mm with finger-joints are considered. Tests on similar specimens without finger-joints are also analyses for comparison. The experiments showed that the finger-joint in the investigated specimens reduced the peak load on the specimen as well as the load in the post-peak stage of plastic deformation. A methodology for modelling the load-displacement relationship taking into account the plastic deformation of wood with a finger-joint in the post-peak stage is proposed. The modelling results do not contradict the experimental data. The basic equation of the proposed mathematical model can be used in further studies to analyse the energy characteristics of the deformation process of wooden elements of building structures.
Asymptotic behavior of null controllability cost for parabolic equations with vanishing diffusivity under Robin and Neumann boundary conditions
Authors: Et-tahri Fouad , Barcena-Petisco Jon Asier , Boutaayamou Idriss , Maniar Lahcen
Published: May 2024

In this paper we study the null controllability cost of a transport-diffusion system under Robin boundary conditions with distributed control and in which the transport coefficient is a gradient field. First, we provide some conditions on transport coefficient and boundary potential to show that the control cost decays exponentially when the viscosity vanishes and the control time is sufficiently large. On the other hand, if the range of the control region by the transport flow does not cover that of Ω, we prove that the control cost explodes exponentially for the Neumann boundary conditions case with vanishing viscosity and all control time.
Investigation of perovskite layer growth from solution on textured substrates
Authors: Riesebeck Florian , Mathies Florian , Yoo Danbi , Trofimov Sergei , Unger Eva , Becker Christiane
Published: May 2024

Surface textures are indispensable to minimize optical losses in perovskite-based solar cells. However, the solution-processing of perovskite layers is often not compatible with textured substrates, and little is known about the film growth thereon. This study aims to elucidate the growth process of perovskite layers from solution on textured substrates and to identify the texture features ensuring compatibility with perovskite solution-processing. Using nanoimprint-lithography we prepared three different periodically as well as randomly textured glass substrates for spin-coated perovskite solar cells, of which one was duplicated from a commercially available texture. During the perovskite crystallization process, a time-resolved in situ photoluminescence measurement was conducted. The photoluminescence signal was not found to substantially alter using textured substrates with texture heights around 500 nm. Optical absorptance spectroscopy and scanning electron microscopic imaging were applied to investigate the growth, crystal structure, and optical properties of solution-processed perovskite on top of different textures. We find that periodic textures with height around 500 nm enable homogeneous solution-processed perovskite layers with optimized optical performance. In contrast, texture heights of several micrometers lead to macroscopic holes in the perovskite film. The results of this study will help to find optimum optical textures for high-efficiency perovskite single-junction and perovskite-silicon tandem solar cells.
Wavefield separation using the f–ξ domain for vertical seismic profiling data
Authors: Liu Baotong , Liu Qiyuan , Jiang Yingshuang , Liu Donglin , Kang Xuefu
Published: May 2024

Wavefield separation is an essential and critical step in data processing of vertical seismic profiles (VSPs). The τ–p transform is one of the effective approaches for separating the VSP wavefield. To further improve the efficiency of the τ–p transform, we developed an f–ξ domain τ–p transform based on the high-resolution Radon transform. The introduction of a new variable ξ removes the frequency dependence of the transform operator. As a result, the transform operator needs to be computed only once for all frequency components, which significantly improves the computational efficiency without decreasing accuracy. Furthermore, because the events of upgoing and downgoing waves are distributed in the vicinity of straight lines with different slopes through the origin in the f–ξ domain, we can easily define a filter to separate the upgoing and downgoing waves. Model tests showed that the wavefields are well separated and that the new method is a factor of ~3 faster than its counterpart in the τ–p domain. The field data example further demonstrates the effectiveness and feasibility of the approach.
A study on the blended teaching practice model for EAP in the Guangdong-Hong Kong-Macao Greater Bay Area
Authors: Wang Xiteng , Liang Qilan
Published: May 2024

With the talents collaborative development in Guangdong-Hong Kong-Macao Greater Bay Area, English for Academic Purposes (EAP) provides support for the cultivation of internationalized talents and international academic exchanges and cooperation, while the in-depth integration of education and information technology also promotes resource integration in various regions and besides, accelerates the integrated development of higher education in the greater Bay Area. Based on the semantic wave theory, the paper discusses the integration of online and offline teaching of EAP from the perspective of cumulative learning. The paper points out that the online and offline teaching should work together to promote the semantic wave, namely, the cycle transition of the semantic gravity and semantic density in order to ensure the cumulative construction of knowledge, hoping to bring enlightenment to the integrated development of higher education in the Greater Bay Area.
Research on the training of family education mentors in China
Authors: Li Guangyan , Wen Tian , Zhang Lu
Published: May 2024

At present, the cultivation of family education mentors is facing both opportunities and challenges, as a unified national standard for the cultivation of family education mentors has not yet been established; The theoretical system construction and talent cultivation of family education are not yet mature; The qualifications of relevant training institutions for family education instructors vary in quality; The widespread recognition of family education as a mentor in the professional society urgently needs to be improved. In the future, the cultivation of family education mentors should start from the following directions: to develop a unified outline and training plan for family education mentors; Accelerate the construction of the theoretical system and talent cultivation of family education disciplines; Establish a qualification evaluation and evaluation system for family education mentors and training institutions as soon as possible; Scientific promotion to enhance the professional identity of family education mentors.
The impact of artificial intelligence technology on the management of front-line employees in manufacturing enterprises: The proposal of a theoretical model
Authors: Chen Chunyan , Chao Yufang , Zhang Xiuhua
Published: May 2024

Artificial intelligence technology has greatly changed production process equipment and technological systems. The changes in production technology systems and environments will inevitably affect people's psychological behavior, thereby affecting employee performance. This article found that artificial intelligence technology has the effects of interpersonal isolation, skill deprivation, innovation opportunity deprivation, and sense of achievement deprivation on frontline employees in manufacturing enterprises, leading to a sense of powerlessness and fatigue among frontline employees, resulting in a decrease in employee satisfaction, an increase in turnover rate, and an increase in insecurity. To address the impact of artificial intelligence technology on frontline employees, traditional human resource management models should be changed, employee care should be strengthened, team activities should be emphasized, life situations should be created, and diverse skills should be developed.
Neuroprotective effects of polysaccharide of Schisandrae Chinensis Fructus in aging mice
Authors: Luo Xiaofeng , Li Jing , Lu Xi , Sun Xin , Li Chunying
Published: May 2024

This study aimed to investigate the effects of Schisandra Chinensis Fructus polysaccharide (SCP) on learning and memory, hippocampal antioxidant activity and Keap1/Nrf2 signal transduction pathway in an aging mouse model. The step-down test was used to observe learning and memory. Biochemical analysis was used to detect Superoxide dismutase (SOD) and malondialdehyde (MDA) levels. Nrf2, HO-1, and Keap1 gene expression in the hippocampus were measured by quantitative real-time polymerase chain reaction (qRT-PCR). SCP can improve the learning and memory ability (P<0.05), increase hippocampal SOD activity, decrease MDA levels, up-regulate Nrf2 and HO-1 gene expressions, down-regulate Keap1 gene expression (P<0.05). Our findings suggest that SCP can improve brain damage in D-galactose-induced aging mice, improve antioxidant enzyme activity, reduce lipid peroxidation, and has obvious anti-aging effects. Its anti-aging activity may be related to activating the Keap1/Nrf2 signal transduction pathway in the hippocampus.
Intelligent enhancement of ancient Chinese murals based on multi-scale parallel structure
Authors: Ge Yuxin
Published: May 2024

Ancient mural artwork preserves the historical background and cultural customs of that time through intricate details and bright colors. However, after the natural environment and man-made damage, these works of art are damaged in color, texture and content and lose their quality. In order to identify and enhance murals with large areas of color damage, we propose a multi-scale parallel GAN and parallel Unet structure, which can extract features from multiple scales or images to adapt to the changing scale of the target and provide a more diverse set of features. This structure can reduce the risk of overfitting the training data by learning more general features. The verification results of indicators such as PSNR on the ancient mural data set show that the method has a certain performance improvement effect.
Exploration of enlightenment experiments for green chemical engineering talents in China higher education - taking Sichuan University as an example
Authors: Yao Shun , Cao Yu , Tang Shengwei
Published: May 2024

How to lead green industry education and promote the development of sustainable society is an urgent issue to be explored. In order to effectively promote the recognition and disciplinary enlightenment of green chemical engineering among involved freshmen in Sichuan University, we designed a set of modular experiments using green solvents and zebrafish as carriers for observation and practice, which emphasized the importance and necessity of green engineering technology, as well as the significance of biomedicine for human health. Its implementation not only helps guide students to establish correct concepts of related specialty and industry, but also effectively stimulates their interest in learning and researching. Through continuous improvement, it is expected to be promoted as a public open experiment in wider range.
“Art world” of yunnan theravada buddhist murals from the perspective of art sociology: A case study based on murals in Jingzhen buddhist temple
Authors: Zhang Qiuying
Published: May 2024

From the perspective of art sociology, this article adopts the research paradigm of “art world” and “cultural production” to carry out a case study on murals in Jingzhen Buddhist Temple in Xishuangbanna and explore the “production” and “autoproduction” process of Theravada Buddhist murals, thereby concluding that the “production” of Theravada Buddhist murals is not the achievement of individual painter, but proves to be co-generated by the “art world”, namely the cooperative network composed of members of the Buddhist Temple Affairs Management Committee, the village group, believers, and painter, under the regulations and influence of various realistic social factors; while due to the publicity and sanctity of Theravada Buddhist murals as well as the particularity of its audience, the relevant “autoproduction” has facilitated the continuous sound interaction between the “production” and “autoproduction” of Theravada Buddhist murals.
Research on juvenile protection based on child sexual assault prevention and crisis intervention
Authors: Zhang Bowen , Yang Zeyu , Mao Jinru , Zhang Hui
Published: May 2024

The protection of minors based on the prevention of child sexual assault and crisis intervention is worthy of research and attention. Based on reviewing the existing literature, the necessity of strengthening the interdisciplinary research of related issues is expounded. It discusses the feasibility of strengthening the interdisciplinary research from the research ideas, contents and methods. It is concluded that “to strengthen based on child sexual assault prevention and crisis intervention of the protection of minors research to realistic innovation” the basic conclusion, put forward “Suggestions to concrete, measures to be effective, this is to ensure that the research work to achieve the expected priority” point of view.
On diagonally structured scheme for nonlinear least squares and data-fitting problems
Authors: Yahaya Mahmoud Muhammad , Kumam Poom , Chaipunya Parin , Awwal Aliyu Muhammed , Wang Lin
Published: May 2024

Recently, structured nonlinear least-squares (NLS) based algorithms gained considerable emphasis from researchers; this attention may result from increasingly applicable areas of these algorithms in different science and engineering domains. In this article, we coined a new efficient structured-based NLS algorithm. We developed a diagonal Hessian-based formulation for solving NLS problems. We derived the quasi-Newton update based on a diagonal matrix scheme subject to a modified structured secant condition. Also, we show that the algorithm’s search direction satisfies a sufficient descent condition under some standard assumptions. Subsequently, we also prove the global convergence of the algorithm and then eventually show its linear convergence rate for strongly convex functions. Furthermore, to show case the proposed algorithm’s performance, we experimented numerically by comparing it with other approaches on some benchmark test functions available in the literature. Finally, the introduced scheme is applied to solve some data-fitting problems
Psychosoziale Versorgungsanforderungen und mögliche Implikationen auf
die Rolle der Psychiatrischen Pflege – Entwicklung eines exemplarischen
Zukunftsszenarios
Authors: Scheydt Stefan
Published: May 2024

Im Fokus der vorliegenden Arbeit steht die Entwicklung eines möglichen
Zukunftsszenarios für die psychiatrische Pflege in Deutschland. Aufbauend auf
den identifizierten Trends der psychosozialen Versorgung wurden bedeutende
Implikationen für die Ausgestaltung einer zukunftsfähigen psychiatrischen Pflege
herausgearbeitet und diskutiert. Das herausgearbeitete Modell beschreibt eine
psychiatrische Pflege, die auf „erweitertem“ Niveau gemeindenah und in einer
multiprofessionellen Umgebung in der Lebenswelt der Betroffenen und ihrer
Angehörigen stattfindet. Sie bindet digitale Elemente der psychosozialen
Gesundheitsversorgung mit ein, während unter anderem personenzentrierte und
diversitäts- sowie traumainformierte Ansätze praktiziert werden. Auch wenn hier
eine psychiatrische Pflege beschrieben wird, die den zu erwartenden Trends und
Entwicklungen der psychosozialen Versorgung gerecht werden könnte, ist eine
kritische Diskussion und eine reflektierte Konsentierung dieser Ideen in einem
interdisziplinären Gremium erforderlich.
Cannabisarzneimittel in der Behandlung psychischer Störungen –
Befunde aus der Cannabis-Begleiterhebung des Bundesinstituts für Arzneimittel
und Medizinprodukte
Authors: Wülfing Felix , Schmidt-Wolf Gabriele , Cremer-Schaeffer Peter , Priebe Kathlen , Schoofs Nikola
Published: May 2024

Hintergrund Seit 2017 können in Deutschland Cannabisarzneimittel zu Lasten
der Krankenkassen verordnet werden.

Methode Ärztinnen und Ärzte waren zur Teilnahme an einer Begleiterhebung
des Bundesinstituts für Arzneimittel und Medizinprodukte (BfArM) verpflichtet.
Diese Arbeit wertet 16 809 Datensätze aus, die zwischen dem 30.03.2017 und dem
31.12.2021 eingingen.

Resultate Die Begleiterhebung erfasste 5582 Fälle mit psychiatrischer
Diagnose. Über die Hälfte der Behandlungen erfolgte mit Dronabinol. 80% der
Behandlungen erfolgten wegen somatoformer Störungen. Schmerz war auch bei den
meisten der Fälle mit anderer psychischer Erkrankung das Zielsymptom. Für alle
Diagnosen schätzten die Ärztinnen und Ärzte in mind. 75% der Fälle die Symptome
als gebessert ein.

Diskussion Die meisten Behandlungen mit Cannabisarzneimitteln bei
psychischen Störungen erfolgten wegen Schmerzen. Die Evidenz aus randomisierten
klinischen Studien für psychiatrische Indikationen ist gering.
Aktuelle Ambulantisierungspotenziale in der Urologie - was bedeutet das IGES Gutachten auf Echtdaten angewendet
Authors: Liedke Lisa , Merseburger Axel S. , Piest Lena , Wille Carsten , Häckl Dennis , Bettin Simon , Elsner Christian
Published: May 2024

Hintergrund Die über das IGES-Gutachten angestoßene Krankenhausreform betont vor allen Dingen auch den Aspekt der Ambulantisierung. Die aktuellen IGES-Vorgaben gehen dabei weiter, als dies bisher der Fall war. Eine Übersetzung dieses theoretischen Potentials in eine praktische Anwendung ist für die Urologie nur sehr vereinzelt vorhanden. Diese Arbeit soll daher an Echtdaten der Urologie das theoretisch berechnete Potential in die Praxis spiegeln.

Materialien und Methoden Aus den §21-Daten des Jahres 2022 der Klinik für Urologie des Universitätsklinikums Schleswig-Holsteins wurde unter der Algorithmus des „Krankenhaus-Struktur-Navigators“ der DKTIG mit Fokus auf die AOP-Katalog Erweiterung angewendet. Es wurden die vom IGES vorgegebenen Ein- und Ausschlusskriterien sowie eine Eingrenzung der Verweildauer auf zwei Tage und eine Mindestfallzahl von 30 Fällen pro Jahr vorgenommen. Nachdem hierbei ein nur sehr geringes Potential von Ziel-DRGs resultiert, wurden die Kriterien weiter modifiziert. Mit diesem Schema fand schließlich eine Plausibilisierung einer ambulanten Behandlungsfähigkeit identifizierter Fälle statt.

Ergebnisse Nachdem sich nach Anwendung der Ein- und Ausschlusskriterien nur eine zutreffende DRG (L18B) ergab, konnten mit den erweiterten Kriterien acht DRGs identifiziert werden. Durch die so ermittelten Fallpauschalen konnten drei geeignete OPS-Codes identifiziert werden:

1. Ureterorenoskopische Entfernung von Steinen aus der Niere mit Lithotripsie (5–550.31)

2. Transurethrale Resektion eines Harnblasentumors, nicht fluoreszenzgestützt (5–573.40)

3. Bougierung eines Ureters, transurethral (5–560.2)

Schlussfolgerung Mit dem momentan durch das IGES definierten Set an Kriterien ist für die Urologie kein großes ambulantes Potential erzielbar. Allerdings haben sich bei der Kriterienerweiterung Themenfelder ergeben, die mit einer Ausweitung der Kriterien gut umsetzbar wären und aktuell systematisch eher im Bereich stationsersetzende Maßnahmen oder Hybrid-DRGs zu sehen sind. Neben einer Klärung der grundsätzlichen ambulanten Umsetzbarkeit der Methoden im Einzelfall ergeben sich hier aber gerade bei multimorbiden Populationen Einschränkungen. Bei der Erweiterung des Kataloges muss daher vom Gesetzgeber dem höheren Risiko und Überwachungsaufwand der Patienten Rechnung getragen werden.
Population Pharmacokinetic of the Diterpenes ent-Polyalthic Acid and Dihydro-ent-Agathic Acid from Copaifera Duckei Oil Resin in Rats
Authors: Aguila Fábio Alves , Bastos Jairo Kenupp , Veneziani Rodrigo C. S. , Nardotto Glauco Henrique Balthazar , Oliveira Larissa Costa , Rocha Adriana , Lanchote Vera Lucia , Ambrósio Sérgio Ricardo
Published: May 2024

Copaifera duckei oleoresin is a plant product extensively used by the Brazilian population for multiple purposes, such as medicinal and cosmetic. Despite its ethnopharmacological relevance, there is no pharmacokinetic data on this important medicinal plant. Due to this, we determined the pharmacokinetic profile of the major nonvolatile compounds of C. duckei oleoresin. The diterpenes ent-polyalthic acid and dihydro-ent-agathic acid correspond to approximately 40% of the total oleoresin. Quantification was performed using LC-MS/MS, and the validated analytical method showed to be precise, accurate, robust, reliable, and linear between 0.57 and 114.74 µg/mL plasma and 0.09 to 18.85 µg/mL plasma, respectively, for ent-polyalthic acid and dihydro-ent-agathic acid, making it suitable for application in preclinical pharmacokinetic studies. Wistar rats received a single 200 mg/kg oral dose (gavage) of C. duckei oleoresin, and blood was collected from their caudal vein through 48 h.
Population pharmacokinetics analysis of ent-polyalthic and dihydro-ent-agathic acids in rats was evaluated using nonlinear mixed-effects modeling conducted in NONMEN software. The pharmacokinetic parameters of ent-polyalthic acid were absorption constant rate = 0.47 h−1, central and peripheral apparent volume of distribution = 0.04 L and 2.48 L, respectively, apparent clearance = 0.15 L/h, and elimination half-life = 11.60 h. For dihydro-ent-agathic acid, absorption constant rate = 0.28 h−1, central and peripheral apparent volume of distribution = 0.01 L and 0.18 L, respectively, apparent clearance = 0.04 L/h, and elimination half-life = 3.49 h. The apparent clearance, central apparent volume of distribution, and peripheral apparent volume of distribution of ent-polyalthic acid were approximately 3.75, 4.00-, and 13.78-folds higher than those of dihydro-ent-agathic.
Sleep Quality among Older Adults in Brazil during the Coronavirus Disease 2019 Pandemic: The Role of Physical Activity
Authors: Bratifische Sandra Aparecida , Cunha Diogo T. , Esteves Andrea Maculano , Corona Ligiana P.
Published: May 2024

Objectives To assess sleep quality and sleepiness among older adults after social distancing during the coronavirus disease 2019 (COVID-19) pandemic and its association with physical activity.

Materials and Methods The present cross-sectional study included a sample of 290 Brazilians aged ≥ 60 years. Subjective sleep quality and sleepiness were assessed using the Mini-Sleep Questionnaire (MSQ) and the Epworth Sleepiness Scale (ESS).

Results Of the 290 participants, 29.7% reported worsening sleep quality during the pandemic, with a mean ± standard deviation (SD) MSQ score of 31.6 ± 8.8. Worsening of the perceived sleep quality during the pandemic and previous COVID-19 diagnoses were associated with higher MSQ scores (p < 0.001 and p = 0.013 respectively). Physical inactivity was not associated with sleep quality but was associated with sleepiness (p = 0.030).

Conclusion It is important to develop strategies that encourage physical activity, among other modifiable health factors, to help improve sleepiness among older adults.
Factors Associated with Poor Sleep Quality in Postpartum Women: A Crossectional Study
Authors: Motta Ana Júlia Pereira , Lucchese Roselma , Leão Graciele Cristina Silva , Rosa Dayane Eusenia , Gonçalves Vilmar De Assis , Mendonça Revora Silverio
Published: May 2024

Objective This study aimed to analyze the factors associated with poor sleep quality in women in the postpartum period who were assisted in a municipality in central Brazil.

Material and Methods This is a cross-sectional study (n = 400) conducted virtually from 2020 to 2021. Sociodemographic and clinical characteristics, self-perceived sleep, and the Pittsburgh Sleep Quality Index (PSQI) were assessed.

Results It was identified that 82% of postpartum women were between 18 and 35-years-old and had an average monthly household income of R$2,339.27 ± 1,812.95. It was also found that 33.50% (95% CI: 28.7–38.0) had sleep disorders (PSQI >10); 70.25% (95%CI 65.8–74.8) had poor sleep quality (PSQI >5); 57.4% (95% CI: 52.0–63.1) had inadequate sleep on weekdays/workdays; and 64.1% (95% CI 59.3–69.2) had unsuitable sleep on weekends/days off. It was found that the factors associated with sleep disturbance were: age between <18 years and >35 years (p = 0.048); difficulty to think clearly (p = 0.043); frequent sadness (p = 0.046); poor sleep quality; low income (p = 0.030); difficulty to think clearly (p = 0.013); and loss of interest in things (p = 0.030). As for sleep on weekdays, the associated factors were: marital status without a partner (p = 0.008); and being a victim of physical violence (p = 0.003). Finally, for sleep on weekends/off: nonwhite skin-color (p = 0.039); and having postpartum depression (p = 0.029).

Conclusion The findings of the present study call attention to the impacts of changes in women's bodies, behavior, and interpersonal relationships caused by the arrival of a newborn. We also highlight the need for a multidisciplinary and comprehensive medical approach in this period.
Left Ventricular Reconstruction after Dor—Sailing Close to the Wind?
Authors: Großmann Clara , Krasivskyi Ihor , Djordjevic Ilija , Mader Navid , Wahlers Thorsten , Eghbalzadeh Kaveh
Published: May 2024

Postinfarction left ventricular aneurysm (LVA) still remains a complication after myocardial infarction with a poor prognosis. Its incidence has decreased due to improved treatment, however, it may have experienced a renaissance due to the coronavirus disease 2019 pandemic. In this retrospective, single-center cohort study, we analyzed n = 17 patients who underwent left ventricular reconstruction after Dor. The results show a mean intensive care unit stay of 8 ± 16 days and a 30-day mortality rate of 6%. Mean postoperative ejection fraction was 44 ± 8% indicating an increase in all but three cases. This suggests that patients with an LVA can be successfully treated, and it is safe when performed by experienced surgeons. Therefore, they should still be considered for surgery early on.
An inverse source problem for the Schrödinger equation with variable coefficients by data on flat subboundary
Authors: Gölgeleyen Fikret , Gölgeleyen İsmet , Yamamoto Masahiro
Published: May 2024

We consider an inverse source problem for the Schrödinger equation with variable coefficients. We prove the uniqueness of solution of the problem by data on a flat subboundary over time interval, under a certain condition of the coefficients of the principal terms. We first reduce the inverse problem to a Cauchy problem for a system of integro-differential equations by using Fourier transform. Next, we establish a pointwise Carleman type inequality which is the key tool in the proof of our main result.
A high-robustness radial intensity-orientated mode decomposition with reliable noise elimination
Authors: Wang Jianshuai , Pei Li , Xu Lin , Hu Kaihua , Li Zhiqi , Gao Han
Published: May 2024

Mode decomposition (MD) provides profound evidence to reveal the internal modal transmission mechanism. However, the indelible noise has always been the main stubborn hindrance in practical MD. In the complex superposition case with a large number of modes, the traditional MD is not capable enough to distinguish the real modal intensity and the annoying noise, sustaining an unacceptable accuracy and fluctuation. This paper proposes a radial intensity-orientated MD (RIO-MD) method with reliable noise elimination. Our approach focuses on the inherent modal radial features in Polar coordinates, getting rid of the traditional two-dimensional image processing in Cartesian ones. The RIO-MD introduces the inherent radial intensity relationship into MD for better extracting mode coefficients. Based on the expectable real radial modal intensity, the RIO-MD enables to recognize and extraction of the three kinds of stubborn noise, including interference pattern noise, device noise, and random noise. The RIO-MD works well in mode decomposition case. The values of correlation coefficients (C) between the experimental and reconstructed image are higher than 93%. The mean square error (MSE) is lower than 3 × 10−3. Both the C and MSE keep stable, with the standard deviation 30 times lower than the other widely used methods, demonstrating the high-robustness of the RIO-MD. Due to the reliable noise recognition, the RIO-MD shows great possibility in mode number expansion.
Acetonitrile real gas phase behavior from quasi-ideal gas to nanodroplets: A microscopical view
Authors: Martínez José M. , Hernández-Cobos Jorge , Pappalardo Rafael R. , Sánchez Marcos Enrique
Published: May 2024

We have applied a recently developed general purpose acetonitrile force field based on first-principles calculations to simulate acetonitrile in the gas phase at different temperatures and densities. These conditions range from nearly ideal to real gas phase behavior and condensation. The molecular dynamics simulation results agree fairly well with the experimental studies available in the literature on the gas samples. The structural analysis of aggregates and their associated interaction energies is examined and related to the early model proposed on molecular association and equilibrium determining the non-ideal behavior. The formation of dimers is mainly responsible for the non-ideal behavior of the gas at very low density, confirming suggested models based on previous experimental studies. However, when the density of the sample rises, the level of aggregation increases and the simple concept of dimerization does not hold anymore. The real behavior adopted by the gas is related to the distribution of molecular structures observed. The macroscopical view of a real gas as a generic interparticle interaction system without a defined form may then be rationalized on the basis of a defined molecular association originated by a distribution of aggregates at the low density regime. The sample with the highest density (∼1.4 × 103 mol m−3) at the lowest temperature exhibits a massive aggregation where most of the acetonitrile (ACN) molecules in the simulation box form a big cluster. Its radial distribution function is similar to that of the liquid ACN. This strongly inhomogeneous distribution in the box can be considered a condensation in the gas phase under specific density-T conditions. This formation opens the door to the potential tuning of its solvent properties as a function of its size in these nanodroplets that in turn are controlled by the density–T conditions.
Time-resolved laser-induced fluorescence spectroscopy using CW diode laser for diagnostics of argon-ion velocity distribution near AC-biased electrode
Authors: Takahashi Ryosuke , Kito Seiya , Eriguchi Koji , Urabe Keiichiro
Published: May 2024

Controlling the ion velocity in an ion sheath by applying an alternating current (AC) voltage to an electrode and/or a substrate is critical in plasma material processes. To externally control the velocity distribution of incident ions on a substrate, the application of tailored-waveform AC voltages instead of sinusoidal voltages has garnered interest in recent years. In this study, to investigate temporal changes in ion-velocity distributions, we developed a time-resolved laser-induced fluorescence spectroscopy (LIF) system using a continuous-wave diode laser as an excitation-laser source. A time-resolved LIF system entails the capture of temporally continuous and spectrally discrete LIF spectra during an AC voltage cycle. By measuring temporal changes in the LIF signal intensity at various excitation-laser wavelengths, the argon-ion velocity distribution near the electrode following the AC voltage can be characterized. The results of applying sinusoidal, triangular, and rectangular bias waveforms indicate that the LIF measurement scheme proposed herein can be used to investigate the dynamic behavior of ion-velocity distributions controlled by tailored-waveform AC voltages.
Gas state equation and flow mechanism of gas–liquid two-phase flow in airlift pump system
Authors: Du Yanlian , Zhu Jingyu , Han Xuanhe , Fu Mengdi , Li Meng , Shen Yijun
Published: May 2024

Airlift pumps (ALPs) have a simple structure and significant application potential. However, previous studies on ALPs have generally assumed that the gas density remains constant. In this paper, the gas state equation (GSE) for ALP is established based on the van der Waals formula, which explicitly considers the density of gas. An electrical resistance tomography system is used to collect the gas void fractions at different heights under different gas flow rates, and an empirical formula for the gas void fraction is established. To verify the effectiveness of the proposed model, high-precision pressure sensors and a high-speed camera are used alongside an electrical resistance tomography system to determine the realistic ALP flow parameters. The results of 409 sets of experiments show that: (1) the gas in ALP cannot be regarded as ideal gas, because the ideal GSE cannot distinguish between different gas flow rates; (2) the state change of gas in ALP is a quasi-equilibrium process, whereby the GSE of ALP can be obtained from the pressures under several locations; (3) the axial pressures predicted by the proposed GSE for ALP are in good agreement with experimental data; and (4) a single parameter of the GSE uniquely determines the state process. The proposed model and the experimental data provide a new methodology and comprehensive references for studying the working mechanism and efficiency of ALPs.
Study on the aerodynamic characteristics and ventilation effects of ultra-high-speed elevator car-counterweight system under the influence of multiple parameters
Authors: Zeng Xiangrui , He Qin , Zhang Ruijun , Cong Dongsheng , Wang Dianqiang
Published: May 2024

When the ultra-high-speed elevator car-counterweight system runs opposite each other, significant piston effects are caused, seriously affecting the elevator operation's stability. In order to explore the aerodynamic characteristics of the whole operation process of a car-counterweight system under multi-parameters, this study first establishes a three-dimensional transient model of the car-counterweight system and a multi-region dynamic layering numerical simulation method based on this model is proposed. Then, the actual elevator experiment validates the correctness of the model and the method. Finally, the influence rules of key parameters on the car's aerodynamic characteristics and ventilation effect are analyzed, and the car's aerodynamic characteristics at intersection time are analyzed emphatically. The results show that with the increase in the blocking ratio, the pressure drag and viscous drag have similar change trends at each stage, but the influence of pressure drag is more significant. The air displacement ratio increases by 34.1%, 75.8%, and 117.3%, respectively. With the increase in the hoistway height, the air displacement ratio decreases by 0.9%, 2.4%, and 2.9%, respectively. The spacing significantly affects the car's aerodynamic characteristics at the intersection time. The drag peak increases by 6.8%, 13.6%, and 20.5% and the lift peak by 21.2%, 47.8%, and 82.5%, respectively.
A novel Fourier neural operator framework for classification of multi-sized images: Application to three dimensional digital porous media
Authors: Kashefi Ali , Mukerji Tapan
Published: May 2024

Fourier neural operators (FNOs) are invariant with respect to the size of input images, and thus images with any size can be fed into FNO-based frameworks without any modification of network architectures, in contrast to traditional convolutional neural networks. Leveraging the advantage of FNOs, we propose a novel deep-learning framework for classifying images with varying sizes. Particularly, we simultaneously train the proposed network on multi-sized images. As a practical application, we consider the problem of predicting the label (e.g., permeability) of three-dimensional digital porous media. To construct the framework, an intuitive approach is to connect FNO layers to a classifier using adaptive max pooling. First, we show that this approach is only effective for porous media with fixed sizes, whereas it fails for porous media of varying sizes. To overcome this limitation, we introduce our approach: instead of using adaptive max pooling, we use static max pooling with the size of channel width of FNO layers. Since the channel width of the FNO layers is independent of the input image size, the introduced framework can handle multi-sized images during training. We show the effectiveness of the introduced framework and compare its performance with the intuitive approach through the example of the classification of three-dimensional digital porous media of varying sizes.
Modification of transition pathways in polarized resonance Raman spectroscopy for carbon nanotubes by highly confined near-field light
Authors: Fujita Yuto , Hayazawa Norihiko , Balois-Oguchi Maria Vanessa , Tanaka Takuo , Shimizu Tomoko K.
Published: May 2024

We observed a modification of transition pathways in polarized resonance Raman spectroscopy during tip-enhanced Raman spectroscopy (TERS) analysis of metallic carbon nanotubes (CNTs). At a spatial resolution reaching up to the sub-nanometer regime, the signal intensity of the typical D-band is observed to be even higher than the intensity of the G-band all over the probed CNTs in TERS imaging. The measured D-band is attributed to the non-vertical transitions of electrons in k-space that are facilitated by highly confined near-field light at the tip–sample junction of our scanning tunneling microscope based TERS system. The D-band signal was observed even when the CNTs were excited by light polarized perpendicular to the tube axis that corresponds to electronic excitations between different cutting line numbers of a CNT. By combining the electron pathways brought about by both the near-field light and its polarization, we found a unique optical transition of electrons of CNTs in near-field Raman spectroscopy.