bluuebunny/crossref_metadata_2025 huggingface dataset:
DİJİTALLEŞME VE KURUMSAL DİJİTAL SORUMLULUK KAVRAMI: GÜNCEL ÖRNEKLERE YÖNELİK BİR İNCELEME
Authors: ACAR Safa
Published: February 2024

Dijitalleşme hayatın her alanında kendini göstermeye devam etmektedir. Özellikle şirketlerin yaptıkları uygulamalar, dijitalleşmenin etkisindedir. Şirketlerin birçok problemini çözüme kavuşturacak fırsatları barındıran dijitalleşme acaba her zaman şirketlere fırsatlar mı sunmaktadır? İşte bu sorunun cevabı bütün dijitalleşme serüvenine çıkan şirketlerin merak ettiği en önemli konulardan birisini oluşturmaktadır. Şirketlerin dijitalleşme sürecinde karşılarına fırsatlar çıktığı kadar tehditler de çıkabilmektedir. Kurumsal dijital sorumluluk, şirketlerin dijitalleşme sürecinde ortaya çıkan kayıpların önüne geçmek amacıyla uygulanması önerilen bir dizi süreçtir. Bu bilgiler doğrultusunda çalışmanın amacı, kurumsal dijital sorumluluk olarak ifade edilen ve dijitalleşmenin meydana getirdiği kayıpları telafi etmek amacıyla uygulanması önerilen yönetim sisteminin hangi noktada olduğunu tespit etmektir. Bu amaç doğrultusunda nitel araştırma desenine sahip bir araştırma gerçekleştirilmiştir. Elde edilen bulgulara göre kurumsal dijital sorumluluk kavramı halen yeni bir kavram olup gelişme aşamasındadır. Uygulama yönüyle kurumsal dijital sorumluluk kavramı incelendiğinde ise çoğu firmanın bu yönde bir çalışmasının olmadığı ancak bazı küresel firmaların bu konuda çeşitli ilke vb. uygulamalar geliştirdiği belirlenmiştir.
Using Subsize Impact Bend Specimens for Estimation of Irradiation and Re-Irradiation Embrittlement of VVER RPV Steels
Authors: Nikolaev Yu. A. , Nikolaeva A. V.
Published: February 2024

Results of impact bend tests of subsize Charpy V-notch-type (CVN) specimens are used in Russia for monitoring both re-irradiation embrittlement of the first generation of VVER-440 (including VVER-440∕179 and VVER-440∕230, i.e., projects B-179 and B-230) reactor pressure vessel (RPV) steels and irradiation embrittlement of VVER-440∕213 RPV steels. For the first generation of VVER-440 RPVs, no surveillance program was foreseen and only subsize specimens (5 by 5 by 27.5 mm and 3 by 4 by 27 mm) can be manufactured from samples taken from the inner surface of the RPV for radiation embrittlement monitoring. For VVER-440∕213 RPVs, 80 % of the surveillance specimens are irradiated with a lead factor greater than 20. Only four specimens of base metal and four specimen halves of weld seam material are irradiated with a lead factor less than 3. Taking into account that full-size (10 by 10 by 55 mm) CVN specimens were used in surveillance programs, using subsize specimens enables to solve the flux effect problem for VVER-440∕213 RPV beltline materials and ensure representativity of surveillance programs. Application of subsize specimens for the estimation of radiation embrittlement requires developing a correlation between transition temperature values evaluated using test results of standard (full-size) and subsize CVN specimens. Such a correlation is discussed.
Fracture Toughness Evaluation of Eurofer97 by Testing Small Specimens
Authors: Serrano Marta , Fernández Pilar , Lapeña Jesús
Published: February 2024

Eurofer'97 is the structural reference material that will be tested in the ITER modules. Its metallurgical properties have been well characterized during the last years. However, more investigations related to the fracture toughness of this material are needed to assess its integrity because this property is one of the most important to design structural components. In the case of structural materials for fusion reactors, the small specimen test technology is being actively developed to investigate the fracture toughness among other mechanical properties. The use of small specimens is due to the small available irradiation volume of the International Fusion Materials Irradiation Facility (IFMIF) and also due to the high fluence expected in the fusion reactor. The aim of this paper is to determine the fracture toughness of the Eurofer'97 steel by testing small specimens of different geometry in the ductile-to-brittle transition region with the application of the Master Curve methodology. The tests and data analysis have been performed following the Master Curve approach included in the ASTM Standard E1921-05, “Standard Test Method for Determination of Reference Temperature, T0, for Ferritic Steels in the Transition Range.” Specimen size effects and comparison of the fracture toughness results with available data in the literature are also discussed.
Clinical empathy and patients’ rights in geriatric care: analysis of the perception of physicians and elderly patients
Authors: Albuquerque Aline , Melgaço Nelma , Cunha Isis
Published: February 2024

The research object of this study is to analyze articulations between clinical empathy and patients’ rights and to propose a set of supporting foundations to build a theoretical basis for the formulation of an aspect of Clinical Bioethics, based on clinical empathy and patients’ rights. The research was carried out involving 5 geriatricians and 4 elderly patients. Geriatric care is permeated by a series of challenges related to the biopsychosocial process of aging, which causes cognitive, emotional, and physical vulnerabilities in elderly patients, which is combined with problematic issues concerning ageism. Thus, elderly patients, in addition to the weaknesses experienced by patients in general, have specificities that make them fear placing themselves in an equal relationship with the physician, by asking questions, inquiring about risks, and bringing their perspective into the decision-making process.
FABP4 and Metabolite Profile in Lipopolysaccharide-Induced Mice Model Treated with Moringa oleifera Ethanol Leaf Extract
Authors: Hanifah Cenia P. , Sulistiyorini Ifa , Sumirat Vanessa A. , Anggraeni Neni , Putri Mirasari , Ghozali Mohammad , Syamsunarno Mas Rizky A.A
Published: February 2024

Sepsis, a life-threatening organ dysfunction resulting from a dysregulated host response to infection, induces changes in blood cells and metabolic alterations. Fatty acid binding protein 4 (FABP4), a lipid chaperone predominantly expressed in adipose tissue, is modulated in sepsis and may contribute to metabolic and immunologic changes. Moringa oleifera (M. oleifera) leaf extract (MOLE) is known to modulate immune system activity, but its potential for treating acute inflammatory conditions like sepsis remains unclear. This study investigates the ability of MOLE to modulate metabolite and hematological profiles in lipopolysaccharide (LPS)-induced sepsis in mice. Thirty-five male Swiss Webster mice (Mus musculus) were divided into five groups, including healthy control pre-treated with 0.5% carboxymethyl cellulose (CMC), an LPS-induced negative control, an LPS-induced positive control treated with dexamethasone (DMX) 7mg/KgBW/day and two MOLE treatment groups with doses of 5.6 and 11.2 mg/20 gBW. Mice received MOLE pre-treatment for three days before LPS induction. Three hours post-LPS injection, the LPS-induced group exhibited leukopenia (1.4 [0.9-2.5] x109 cells/L) and a 68.3% increase in triglyceride levels. However, the MOLE-treated group showed improved erythrocyte levels compared to the positive control group; [(9.9(9.3-10.0) x1012 cell/L) vs (7.7(7.0-9.0) x1012 cells/L), p<0.05]. The study suggests that MOLE administration may positively impact sepsis conditions, particularly by enhancing RBC levels. Further research with an extended observation period is recommended to address limitations in metabolite level assessment.
Stopień opanowania narzędnika i biernika liczby pojedynczej i mnogiej a transfer językowy wśród studentów z Ukrainy i Białorusi na początkowych poziomach zaawansowania
Authors: Myśliwiec Iwona
Published: February 2024

Niniejszy artykuł jest częścią badań prowadzonych wśród studentów z Ukrainy i Białorusi studiujących w Polsce. Badania te przeprowadzono z wykorzystaniem autorskiego testu sprawdzającego efekt opanowania dwóch przypadków – narzędnika i biernika liczby pojedynczej i mnogiej oraz przyswojenia umiejętności rozpoznania form tych przypadków, a w dalszym procesie – posługiwania się nimi w kontekście interferencji językowej wśród osób, dla których język słowiański (ukraiński, rosyjski, białoruski) jest językiem pierwszym. Celem artykułu jest przedstawienie, analiza i omówienie części zamkniętej testów przeprowadzonych wśród uczestników kursu języka polskiego prowadzonych na różnych poziomach zaawansowania. Badanie wykazało istnienie interferencji na każdym z poziomów, z dużą częstotliwością ich występowania. Analiza ankiet dowodzi braku zadowalającego efektu w opanowaniu zagadnień gramatycznych, czego jednym z podłoży może być brak świadomości językowej uczących się.
Sarcoidosis of the Skin as an Interdisciplinary Problem
Authors: Samtsov Alexey V. , Kryukov Evgeniy V.
Published: February 2024

Sarcoidosis is a disease of unknown etiology characterized by the formation of epithelioid cell granulomas in several organs or tissues without caseous necrosis (fibrinoid necrosis may occur). With sarcoidosis, almost all organs and tissues can be affected, which determines the interdisciplinary nature of the problem. Skin sarcoidosis is one of the most common manifestations of systemic sarcoidosis. At the same time, the role of dermatologists in the diagnosis of sarcoidosis is exceptionally large, since skin lesions are often the key to the discovery of systemic sarcoidosis, which allows internists to purposefully and timely diagnose and treat lesions of internal organs. Skin rashes in patients with sarcoidosis may occur secondarily against the background of specific lesions of the lungs, intrathoracic nodes and other internal organs, however, skin sarcoidosis may also develop primarily. All forms of skin sarcoidosis may be the only manifestation of the disease, and it is impossible to distinguish clinically and histologically between skin changes in systemic sarcoidosis and skin lesions alone. Treatment of skin sarcoidosis often presents great difficulties and includes, depending on the prevalence and activity of the process, local (corticosteroids, tacrolimus) and systemic therapy (immunomodulators, immunosuppressors, TNF inhibitors).
Ectopic ACTH Syndrome: Possibilities of Modern Diagnostics
Authors: Grineva Elena N. , Tsoy Uliana A. , Ryzhkova Daria  V.
Published: February 2024

The ectopic ACTH syndrome (EAS) is a constellation of clinical signs and symptoms caused by chronic excess production of cortisol by the adrenal glands due to stimulation by adrenocorticotropic hormone (ACTH) of extrapituitary origin. EAS is a rare pathology, it accounts for approximately 20% of all cases of ACTH-dependent hypercortisolism and up to 10% of all causes of endogenous autonomic cortisol production, however, it is often associated with severe hypercortisolism and is a life-threatening condition. The sources of ectopic secretion of ACTH are neuroendocrine tumors (NET), which differ in histological type, malignant potential, clinical course, and also have different, often difficult to detect localization. Early identification of ACTH -producing NET reduces the risk of death of the patient both from severe hypercortisolism and the tumor itself. The paper describes the features of the course of EAS, the possibilities of its diagnosis, and presents an algorithm for EAS diagnosis, created on the basis of the latest achievements of Russian and world medicine.
BORN GLOBALS: UN ACERCAMIENTO A LA OPORTUNIDAD DE EMPRENDIMIENTO
Authors: Garcés Bautista José Luis , Estelles-Miguel Sofía , Peris-Ortiz Marta , Valero Cordoba Gladys Mireya
Published: February 2024

La escasa información sobre empresas globales de la región, impide el aprovechamiento de los tratados mencionados. Durante el presente estudio se ha evidenciado que existen casos específicos sobre este tipo de empresas a nivel internacional, las cuales se convierten en una gran oportunidad para el emprendimiento, de modo que fomentan la productividad a todos los niveles, en sectores claves para la economía del país. El objetivo del presente artículo es realizar un estudio del estado del arte de las empresas nacidas globales o “Born Globals”, y al mismo tiempo analizar los casos existentes a nivel nacional e internacional. Para dicho estudio se ha realizado un profundo análisis bibliográfico del tema, para a continuación extraer las fuentes más importantes del mismo. Luego se analizan los resultados y se obtienen conclusiones y líneas de futuro para el presente trabajo. Este trabajo forma parte de un estudio más profundo con el que se va a realizar una tesis en emprendimiento.
PROGRAMAS RELACIONADOS CON NEGOCIOS INTERNACIONALES Y EN EL EXTERIOR
Authors: Rincón-Báez William Umar , Becerra Plaza Gisèle Eugenia , Arias-Velandia Nicolas
Published: February 2024

Para el duodécimo boletín del Observatorio de Ciencias Administrativas de ASCOLFA, se presentan los datos de los programas relacionados con negocios internacionales y exterior del área de conocimiento (AC) de Economía, Administración, Contaduría y afines. Se estudian sus características y sus resultados en las pruebas de estado, en las bases de datos del Sistema Nacional de Información de la Educación Superior (SNIES) y en las competencias genéricas en FTP-ICFES1.
EMPRENDIMIENTO JUVENIL SOCIAL EN EL SECTOR TEXTIL MYPYMES AMB 2020 EN TIEMPOS DE COVID 19
Authors: Espitia González Sandra Marcela
Published: February 2024

El sector industrial del corredor textil de confección ha presentado una dinámica significativa en los últimos años tanto en el contexto de Colombia como en el mundo. Sin embargo, presenta algunas debilidades en aspectos financieros, administrativos y tecnológicos, lo cual requiere una especial atención en la cadena de valor, de manera que logre fortalecer la productividad y posicionamiento en el mercado nacional e internacional con productos innovadores acordes a las nuevas tendencias de moda. Es por ello, que esta investigación pretende realizar el emprendimiento juvenil sociales en el sector textil Bucaramanga, con el fin de fortalecer los indicadores de competitividad de esta industria y así mismo los lazos de integración comercial entre los dos países, coadyuvando a las madres cabezas de hogar quienes son principalmente las que conforman el tejido empresarial de este. Este estudio es tipo cuantitativo, correlacional mediante la aplicación de una encuesta estructurada, la cual será validada bajo la técnica de alfa de Cronbach. La población objeto de estudio para esta investigación será Mí pymes pertenecientes al sector enunciado ubicadas en el municipio de Bucaramanga – Colombia.
ANÁLISIS DE LOS PROGRAMAS Y POLÍTICAS QUE OFRECEN LAS INSTITUCIONES FINANCIERAS EN EL FORTALECIMIENTO DE LAS EMPRESAS DE TURISMO EN LOS DEPARTAMENTOS DE CAQUETÁ Y QUINDÍO PARA LA INNOVACIÓN
Authors: Giraldo Correa María Patricia , Beltrán Chica John Jairo
Published: February 2024

El presente documento es el resultado de un proceso investigativo desarrollado en los departamentos de Caquetá y Quindío, que evaluó el impacto de las entidades financieras en la competitividad sistémica del sector turismo. Para lograrlo, se parte del enfoque sistémico de la competitividad, a través del análisis de los aspectos y características del sector turismo, así como de su relación con las entidades financieras. Luego, se identifican los factores socioeconómicos que dinamizan los procesos de gerencia, innovación y tecnología adoptados por las empresas de turismo en ambos departamentos. Este estudio se realizó a partir de un trabajo aplicado de carácter exploratorio-descriptivo, que, basado en los principios de la teoría económica y administrativa, permitió diseñar y aplicar una herramienta metodológica para identificar las características del portafolio de servicios de las entidades financieras y los factores que midieron su  impacto y participación en el desarrollo de la competitividad sistémica de las empresas turísticas (alojamientos, servicios, transporte y restaurantes). Finalmente, se formulan reflexiones y propuestas orientadas a las entidades financieras, las empresas turísticas y los organismos gubernamentales, para que diseñen políticas y lineamientos que impulsen el fortalecimiento y la competitividad de esta actividad económica en las regiones; estableciendo la contribución de este tipo de investigaciones para ampliar la frontera de conocimiento y para resaltar papel de las entidades públicas y privadas en la consolidación del territorio.
COMPETENCIAS DIDACTICAS EN LA FORMACIÓN DEL MANAGEMENT EMPRENDEDOR: UN PROCESO DE APRENDIZAJE EN INSTITUCIONES DE EDUCACION SUPERIOR
Authors: Mosquera Carrascal Adriana , Peñaranda Peñaranda Marta Milena , Bayona Trillos Ramón Armando
Published: February 2024

El proceso de aprendizaje del management emprendedor requiere competencias didácticas específicas que le permitirán desarrollarse como empresario. El objetivo consistió en determinar las competencias didácticas presentes en los profesores universitarios para formar el management emprendedor. Se utilizó el método de enfoque cuantitativo y el tipo de investigación descriptiva, no experimental de diseño transeccional, mediante lo cual se obtuvo información de 219 profesores de 4 universidades que tienen presencia a nivel nacional. Dentro de los resultados se evidencia como fortaleza la motivación otorgada por sus profesores. Se concluyó que las competencias didácticas están relacionadas con el ser del management emprendedor.
IMPACTO DE LAS PRÁCTICAS DE GESTIÓN HUMANA EN LA EFICIENCIA ORGANIZACIONAL DE PEQUEÑAS Y MEDIANAS EMPRESAS: REVISIÓN DE LITERATURA
Authors: Taborda Morales Yarmin Lorena , Soto Jáuregui Cristian , Yela Ruíz Valentina
Published: February 2024

El objetivo de este proceso es evidenciar la producción académica que se ha desarrollado, en los últimos años, con miras a identificar, reconocer y evaluar el impacto de las prácticas de gestión humana en la eficiencia organizacional en pequeñas y medianas empresas. La búsqueda fue elaborada siguiendo criterios como: tipo de bases de datos, tipo de texto, años de publicación, descriptores, entre otros; con base en ello, se presenta a manera de conclusión, resultados que indican que las prácticas de gestión humana van en diversas direcciones y que estas impactan, de manera positiva, la eficiencia organizacional en coherencia con una definida, pertinente y estructurada planeación estratégica, es decir, solo cuando logra estar articulada con cada uno de los elementos claves del negocio sin poner en desbarajuste por el hacer, el ser y estar de las personas en las empresas. Sin embargo, de acuerdo con la revisión no se ha llegado articulación general que permita dilucidar el impacto de estas prácticas en las pequeñas y medianas empresas, dado que las múltiples investigaciones abordan de manera conceptual la relación entre la eficiencia organizacional y la aplicación de prácticas, pero no existen procesos metodológicos que garanticen ello.
Ultrafast Spectroscopy at the Central Laser Facility
Authors: Donaldson Paul M. , Sazanovich Igor V. , Malakar Partha , Maiti Sourav , Towrie Mike , Greetham Gregory M.
Published: February 2024

In this article, we will examine ultrafast spectroscopy techniques and applications, covering time-resolved infrared (TR-IR) spectroscopy, time resolved visible (TA) spectroscopy, two-dimensional infrared (2D-IR) spectroscopy, Kerr-gated Raman spectroscopy, time-resolved Raman and surface sum-frequency generation (SSFG) spectroscopy. In addition to introducing each technique, we will cover some basics, such as what kinds of lasers are used and discuss how these techniques are applied to study a diversity of chemical problems such as photocatalysis, photochemistry, electrocatalysis, battery electrode characterisation, zeolite characterisation and protein structural dynamics.
Geopolitical determinants of the constitutional position of the President of Ukraine as a guarantor of sovereignty and territorial integrity of the state
Authors: Olechno Artur
Published: February 2024

The author, based on the legal-dogmatic method and the analysis of the constitutional practice, presents the amendments I of the Constitution and legislation of Ukraine from the point of view of the constitutional position of the President as the guarantor of state security. Author, based on it, proposes a new periodization of the last several decades of Ukrainian constitutionalism.
The Institution of Contractual Probation in the Penal Code of the Kingdom of Sweden – Introductory Remarks
Authors: Wróbel Aleksander
Published: February 2024

This study aims at analyzing an institution regulated in the Penal Code of the Kingdom of Sweden designated as contractual probation. This is a solution introduced into the criminal law of Sweden in 1988 and was intended to be, on the one hand, an alternative to a punishment of imprisonment, and, on the other hand, it is designed to fill the gap left by the removing from the criminal law of Sweden the protective measure in the form of therapy – outpatient treatment. The focal part of the solution is the nature of the crime committed, the specific health condition of the offender requiring treatment and the fact that this health condition of the offender is directly related to the commission of the crime, as well as the expression of the offender’s willingness to be treated in accordance with a treatment plan. This article is the first in a series of works aiming to present the solutions in force in the Kingdom of Sweden. Further articles will concern the juxtaposition of Polish solutions with Swedish ones in order to build a model that will be a response to the difficulties plaguing the Polish system.
The essence and purpose of per-form (per procura) vote for people with disabilities
Authors: Rogacka-Łukasik Anna
Published: February 2024

The aim of this publication is to present the essence of the institution of vote per procura as an alternative method of voting for people with disabilities. A circle of voters has been presented, to which a disabled voter can give the right to cast a vote, as well as the qualifications that must be met by a candidate for a disabled voter’s representative. A quite strongly formalized procedure for granting the power of attorney to vote and drawing up an act of such power of attorney has been presented. While positively assessing the voting institution as per procura, at the end it was stated that this type of voting is still an “unresolved constitutional problem” and is often criticized.
Directions and instruments of informatization of the civil proceedings from a perspective of implementation of the procedural principles
Authors: Trachta Aleksandra
Published: February 2024

The aim of the article is to analyze the directions and tools of computerization of civil proceedings and their impact on the implementation of the main procedural principles. The issue of computerization of the judiciary has a multifaceted nature. It results from the combination of traditionally understood procedural institutions with concepts of a technical nature. The development of the computerization process basically occurs in two directions: complexity and hybridity (optionality). Currently, it is at an advanced level, although the process still requires emendations and optimization. The computerization of civil proceedings supports the implementation of main procedural principles in the traditional formula. A wide range of IT instruments and procedural institutions contribute to more complete implementation of them in the process.
PROMISING DEVELOPMENTS AND SCIENTIFIC TECHNOLOGICAL ACHIEVEMENTS IN GEOLOGICAL EXPLORATION IN THE MIDDLE EAST REGION
Authors: Yusifov T.Yu. , Anasova V.G. , Khazipov I.N.
Published: February 2024

Technological and economic trends in the development of the oil and gas industry form promising directions for the development of geological research, oil and gas fields development and hydrocarbons production. Currently, in the world oil and gas production practice, there is a tendency to increase the share of involvement in the hard-to-reach and hard-to-recover reserves development, which results in the cost of geological exploration increasing. It is important to minimize these costs by improving existing and developing new technological solutions. Increasing the efficiency and knowledge intensity of new technologies being introduced is the most promising strategy for exploration activities, oil and gas fields development and exploitation.The current conditions for the exit of most foreign companies from the Russian sector of the oil and gas industry, including the search for potential oil locations, require the development or maintenance at the proper level of own innovative and knowledge-intensive solutions that ensure the further systematic development of the geological exploration sector. A potential vector in this direction could be technology transfer from foreign countries, including most of the Middle East and North Africa countries. The innovative activities of up stream in these countries (including in terms of geological exploration) determine the trends in the development of international geological exploration technologies, as well as potential foreign companies for the systematic institutionalization of mutually beneficial relations between Russian and foreign oil businesses.Saudi Arabia, Israel and Iraq companies develop promising innovative solutions for the oil and gas industry exploration sector, including attracting foreign technologies to their market. Saudi Arabian companies are the most active companies with a significant increase in the number of innovative technologies. The main focus of the innovative solutions developed by these companies for the geological exploration sector is: improving methods of laboratory and geophysical research, improving the quality of seismic exploration, as well as introducing mathematical modeling modern trends in geological exploration.
METHOD FOR FORECASTING INCREASE IN LIQUID PRODUCTION FOR OPTIMIZE SELECTION OF CANDIDATES FOR HYDRAULIC FRACTURING
Authors: Polezhaev V.O. , Ramazanov R.R. , Yapparov I.I. , Zhdanov L.M. , Oleinikov V.S. , Mingazov A.F.
Published: February 2024

Over the past 20 years, the structure of reserves of Russian oil fields has undergone significant changes: with a general increase in reserves, there has been a significant increase in the share of hard to recover reserves (HTR). In the HTR structure of the Russian Federation, low-permeability and heterogeneous reservoirs are identified as the main subgroup (64 %), in 2022, approximately 30 % of all Russian oil was produced from HTR (166 from 535 million tons). In such reservoirs, to maintain and ensure high levels of oil recovery, a workovers such as hydraulic fracturing (HF) is used.Petroleum production companies have various technical and infrastructal capabilities for the selection of candidate wells for workover. Some oil companies use the support of design institutes and service companies that mining andhave specialized geological software products for monitoring and selection of workovers, others make do with the knowledge and skills of selecting their own specialists. However, due to the development of residual recoverable reserves and the unprofitability of the workover every year to select candidate wells, it is becoming increasingly difficult to select candidate wells. Working out the entire well stock and selection candidate wells using standard techniques takes a huge amount of time for a specialist. The article proposes a solution to the topical issue of optimizing the selection of candidate wells for hydraulic fracturing by predicting the dynamics of production wells based on historical data for various geological conditions. The developed method for forecasting the flow rate of liquid and oil on the basis of the rate of change in reservoir pressure and water cut of the well allows you to predict the flow rate for two years ahead, monthly estimates the possible increase from hydraulic fracturing and allows you to determine the optimal time for repeated or primary hydraulic fracturing at the well. This approach sharply narrows the number of potential candidates from a coupe of hundred to two to three dozen potential candidates.
Book Review: Linguistics for Legal Interpretation Terrence R Carney (UJ Press Auckland Park 2023)
Authors: Laubscher Michael
Published: February 2024

This contribution provides a review of the publication: “Linguistics for Legal interpretation” written by Prof TR Carney
The Effect of Knee Tuck Jump and Jump-To-Box Plyometric Training on Female Students’ Leg Muscle Strength and Flexibility in Volleyball Extracurricular Activity
Authors: Rismayanthi Cerika , Salam Nur Alfitra , Alim Abdul , Miftachurochmah Yulvia
Published: February 2024

Study purpose. This study aimed to investigate the effects of Knee Tuck Jump or Jump to Box plyometric training and to determine their effectiveness in increasing leg muscle strength and flexibility in female students participating in volleyball extracurriculars.
Materials and methods. This study used a quasi-experimental design. Twenty-four female students were randomly selected as samples and then divided into two categories: 12 students receiving Knee Tuck Jump training (age: 17.08±0.51) and 12 students receiving Jump to Box training (age: 17.00±0.60). All participants performed the initial and final tests using the Vertical Jump and sit-and-reach tests. To analyze the data, the t-test was used to determine the differences in variables between the pretest and posttest in the experimental group.
Results. In the Knee Tuck Jump group, a significant improvement in VJ (P=0.000) and sit-&-reach tests (P=0.000) was observed. In addition, Knee Tuck Jump was considered to be more effective in increasing the students’ flexibility, because the t value of sit-&-reach test (14.075) was higher than that of VJ (13.811).
Similarly, the Jump to Box group also showed a significant improvement in VJ (P=0.000) and sit-&-reach (P=0.000) tests. However, Jump to Box was deemed to be more effective in increasing the students’ leg muscle strength, as the t value of VJ (26.086) was higher than that of sit-&-reach test (9.594).
Conclusions. Based on the research findings, it can be concluded that plyometric exercises, specifically KTJ and JB, have a significant and positive impact on the lower limb muscle strength and flexibility in female students participating in volleyball extracurricular activities. Despite both demonstrating significant positive effects, KTJ training is more effective in improving flexibility compared to JB, while JB is more effective in enhancing lower limb muscle strength compared to KTJ.
Phytochemical Compounds in Sea Cucumber Have the Potential to Reduce Oxidative Stress and Inflammation Due to Exercise: Systematic Review
Authors: Ayubi Novadri , Padmasari Dyah Fitria , Komaini Anton , Syafawi Atika , Ardha Muchamad Arif Al , Dafun Procopio B. , Ming Jiang Wen , Lesmana Heru Syarli , Putri Dhea Regita Sastika
Published: February 2024

Study purpose. This study aims to analyze and highlight the potential of Sea Cucumber in reducing oxidative stress and inflammation caused by exercise.
Materials and methods. The study is a type of systematic review research using searches from various journal databases such as Science Direct, Pubmed and Web of Science. The inclusion criteria in this study were journals published in the last 5 years which discussed sea cucumber, oxidative stress, inflammation and exercise. Furthermore, the exclusion criteria in this research are journals that are not reputable or are not indexed by Scopus and Web of Science. A total of 1038 articles from the Science Direct, Pubmed and Web of Science databases were identified. A total of 8 articles that met the inclusion criteria were selected and analyzed for this systematic review. For standard operations, this study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) assessment.
Results. The results of this systematic review research report that the strong phenolic content found in Sea Cucumber has anti-oxidant properties which may reduce oxidative stress. Furthermore, the anti-inflammatory properties of sea cucumbers have the potential to reduce uncontrolled inflammation caused by intense exercise.
Conclusions. The phenolic content in sea cucumbers has strong anti-oxidant properties in reducing oxidative stress. In addition, the anti-inflammatory properties of sea cucumbers may reduce uncontrolled inflammation caused by exercise. In this case, sea cucumbers have an anti-inflammatory effect by suppressing the secretion of pro-inflammatory cytokines. Through this systematic review, we recommend that future studies should perform clinical trials on the potential effects of sea cucumber on oxidative stress biomarkers and inflammatory biomarkers after exercise.
Social Media Political Information Use and Political Participation of the Net Generation
Authors: Tan Jue Jun
Published: February 2024

Given the pervasiveness of social media in our contemporary communication environment, this paper explored the aptitude of social media use for political information in empowering the wired youth with more diverse political information which is deemed as key precursor of political participation. To be more specific, this paper examined how the utilisation of political information on social media predicts political knowledge, political efficacy, and different modes of political participation (offline, online, and cyber) of the Net Generation. There were 379 Malaysian students aged between 18 and 24, who depend extensively on social media platforms as their primary reservoir of political news and information took part in a self-administered online survey questionnaire. Among the key findings of the current study are: (i) political informational use of social media predicts political efficacy but not political knowledge; (ii) political informational use of social media predicts offline, online, and cyber political participation via political efficacy; (iii) political knowledge does not predict political participation; meanwhile (iv) political efficacy predicts political participation. All in all, political informational use of social media holds the most potent positive effect on political efficacy.
Model Tarikan Metafora Visual Ketakutan bagi Meningkatkan Perhatian kepada Pesanan Khidmat Awam
Authors: Ahmad Zul Imran , Mohamad Salleh Mohd Azul , Mustaffa Normah
Published: February 2024

Peranan Pesanan Khidmat Awam (PSA) dalam menarik perhatian masyarakat kepada mesej kesedaran semakin mencabar berikutan perkembangan teknologi visual yang telah meningkatkan citarasa penonton. Demi memaksimumkan perhatian dan perubahan sikap, ancaman ketakutan biasa digunakan sebagai retorik visual (RV) dalam pelbagai kempen tempatan terutamanya yang melibatkan kesihatan. Namun begitu, implementasi pujukan ketakutan yang kurang disandarkan kepada kajian empirikal sering kali gagal menarik perhatian, malah mencetuskan tindak balas defensif penonton. RV ketakutan gagal disebabkan kekurangan model persuasif ketakutan yang khusus untuk berdiplomasi dengan pengetahuan dan pengalaman penonton. Kelemahan ini dilihat lebih jelas daripada penonton sasaran yang turut memiliki kecenderungan tertentu seperti ketagihan permainan video dalam kes kelaziman permainan bermasalah (Problematic Gaming – PG) di Malaysia. Timbul persoalan mengenai apakah pendekatan RV ketakutan yang lebih sesuai bagi tarikan perhatian dan kurang risiko penolakan. Justeru, strategi tarikan PSA sedia ada memerlukan konsep yang lebih peka kognitif dan afektif penonton. Sehubungan dengan itu, matlamat kertas ini adalah untuk membincangkan dan mencadangkan konsep Metafora Visual Ketakutan (FVM) sebagai RV PSA yang baharu. Pemilihan konstruk rangsangan MV terbaik daripada tipologi Teori Metafora Bergambar (TMB), Teori Retorik Visual (TRV), atau Konsep Struktur Visual (KSV) yang sudah terbukti berkesan dalam periklanan komersial boleh digabungkan dengan komponen ancaman daripada model pujukan ketakutan Extended Parallel Process Model (EPPM) bagi meningkatkan potensi tarikan perhatian. Secara teoretikal, FVM menarik perhatian penonton menerusi daya tarikan kognitif dan afektif yang jauh lebih baik daripada MV mahupun RV biasa. Kesimpulan daripada kajian ini dijangka dapat menyumbangkan sebuah konsep yang boleh diuji dan disahkan secara empirikal.
Buenas Prácticas de Manufactura de carnicerías y frecuencia de Escherichia coli productor de toxina Shiga y Salmonella spp. en carne molida de carnicerías de Asunción, Paraguay
Authors: Weiler Natalie , Orrego María , Álvarez Mercedes , Ortiz Flavia , Martínez Jazmín , Dure Felicita , Florentin Melisa , Piris Laura , Pérez José , Domínguez Myrna , Lacarruba Carla , Leotta Gerardo
Published: February 2024

La inocuidad de la carne comercializada debe estar garantizada en la cadena de producción, para evitar enfermedades transmitidas por alimentos (ETA). Escherichia coli productor de toxina Shiga (STEC) y Salmonella spp. pueden encontrarse en el tracto gastrointestinal de los bovinos y contaminar la carne de consumo humano, pudiendo causar enfermedades en el hombre. Este trabajo tuvo como objetivo evaluar las condiciones higiénico-sanitarias de 52 carnicerías localizadas en Asunción y detectar la frecuencia de STEC y Salmonella spp. en muestras de carne molida. Las condiciones higiénico-sanitarias se evaluaron mediante la estimación del riesgo, utilizando una escala de clasificación por categorías. La detección de STEC y Salmonella spp. se realizó por PCR en tiempo real. En la evaluación inicial, se clasificaron a 33% de las carnicerías como de alto y moderado riesgo. Se detectó STEC no-O157 en un 50% (130/258) de las muestras y Salmonella spp. en un 11% (29/258). Se realizaron acciones de mejora. En la etapa post-intervención, no se detectaron carnicerías de alto riesgo. En el muestreo de seguimiento se detectó un 29% (66/237) de muestras positivas para STEC no-O157 y 7% (16 /237) para Salmonella spp. Este estudio permitió realizar recomendaciones específicas y detalladas a cada carnicería, lo que tuvo un efecto significativo en la mejora de sus condiciones. Esta situación resalta la importancia de continuar fortaleciendo la vigilancia multisectorial y multidisciplinaria. Es imperativo que los establecimientos que se dedican al rubro, implementen las Buenas Prácticas de Manufactura (BPM) como una medida para reducir los riesgos asociados.
Letter to a Young Scientist
Authors: Kress Stephen W.
Published: February 2024

No abstract available.
Identification of protein components of the transformation system in the cell line of immortalized human keratinocytes HaCaT exposed to surfactants
Authors: Shkrigunov T.S. , Vavilov N.E. , Samenkova N.F. , Kisrieva Yu.S. , Rusanov A.L. , Romashin D.D. , Karuzina I.I. , Lisitsa A.V. , Petushkova N.A.
Published: February 2024

Using the method of shotgun mass spectrometry, we have evaluated changes in the proteomic profile of HaCat cells in response to the treatment with sodium dodecyl sulfate (anionic surfactant) and Triton-X100 (non-ionic surfactant) in two concentrations (12.5 µg/mL and 25.0 µg/mL). The study revealed induction of orphan CYP2S1 (biotransformation phase I) in response to Triton-X100. We have identified proteins of II (glutathione-S-transferases, GSTs) and III (solute carrier proteins, SLCs) biotransformation phases, as well as antioxidant proteins (peroxiredoxins, PRDXs; catalase, CAT; thioredoxin, TXN). Thus, proteins of all three xenobiotic detoxification phases were detected. The presented results suggest a new prospect of using HaCaT keratinocytes as a model of human epidermis for studying the metabolism of drugs/toxicants in human skin in vitro.
Abstract Machines in J. G. Ballard’s "High-rise"
Authors: Tuğlu Atamer Begüm
Published: February 2024

This article sets out to explore how J. G. Ballard’s High-Rise (1975) can be read through Deleuze and Guattari’s concepts of rhizome, abstract machines and schizophrenia. The social structure of the Seventies in England, High-Rise as a building and High Rise as a novel are connected to one another to portray a rhizome that manifests a dystopian answer to the inquiry of human nature. High-Rise can be studied as an abstract machine since it is a machine of fiction through which the readers question the meaning of humanity. High-Rise, the building, is also an abstract machine in itself since it operates as a means to reveal the constant process of becoming under late capitalism. Therefore, this article aims to reveal the Deleuze-Guattarian dynamics in High-Rise in relation to High-Rise, the building, by focusing on the social elements that expose the schizophrenic aspects of late capitalism.
Antenatal care at rivers state university teaching hospital, southern Nigeria: who and when?
Authors: Nonye-Enyidah Esther Ijeoma , O. A. Altraide Basil , I. Jumbo Awopola , Enyidah Nonyenim Solomon , Terhemen Kasso
Published: February 2024

Background: Antenatal care prepares pregnant women physically and psychologically for birth and parenthood. It also prevents, detects and manages health problems affecting mothers and their babies. Objectives were to identify and characterise those attending antenatal care at RSUTH and when they register for antenatal care.
Methods: A retrospective study conducted from 1st January, 2015-31st December, 2020 at ANC of RSUTH. Records of 9990 pregnant women who booked for antenatal care were retrieved and reviewed. Socio-demographic characteristics and gestational age at booking were studied. Data was analyzed using SPSS version 23.0. P value <0.05 was statistically significant.
Results: During the study period, 9990 pregnant women booked for antenatal care. Most (23.3%) registered in 2016. Mean age at booking was 31.4±4.7 years. Highest age group (62.4%) was 30-39 years. Modal parity was para 0 and majority (37.5%) were para 2-4. Mean gestational age at booking was 20.5±7.5 weeks. More than 70% had tertiary education and 67.9% were traders and civil servants. More than 97% were married and 58.3% registered in their second trimester. When gestational age at booking was compared with the various socio-demographic parameters, those with the differences statistically significant and associated with late booking were educational level, age, parity, occupation and employment status.
Conclusions: Most women at booking were in their thirties, second trimester, married, multiparous, working class and had tertiary level of education. Most socio-demographic parameters showed statistically significant differences when compared with the gestational age at booking.
Evaluating the toxicity of capecitabine-cisplatin versus gemcitabine-cisplatin regimens for palliative chemotherapy in advanced biliary tract carcinoma
Authors: Hasan Tariq , Rahid Sarwar S. M. , Sarkar Fatema , Jahan Ishrat , Mostari M. Shabnam
Published: February 2024

Background: Advanced biliary tract carcinoma is a malignancy associated with poor prognosis and limited treatment options. This study aimed to compare the treatment effects in terms of toxicities of Capecitabine-Cisplatin and Gemcitabine-Cisplatin regimens as palliative chemotherapy for ABTC in Bangladesh.
Methods: This quasi-experimental study was conducted at the Department of Oncology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, involving 78 patients with histopathologically confirmed ABTC (AJCC Stage IV). Participants were divided into two groups: Arm-A received Capecitabine-Cisplatin, and Arm-B received Gemcitabine-Cisplatin. Treatment response, hematological and non-hematological toxicities were assessed and compared between the two groups.
Results: No significant differences in baseline demographic and clinical characteristics were observed between the two groups. Arm-A demonstrated a higher rate of partial response in the final assessment (51.28% vs. 41.03%, p=0.029). Acute hematological toxicities were more frequent in Arm-B, with a higher incidence of Grade 2 and 3 anemia, neutropenia, and leukopenia (p<0.05). Non-hematological toxicities were comparable, except for Hand-Foot Syndrome, which was significantly higher in Arm-A (p=0.03).
Conclusions: The Capecitabine-Cisplatin regimen exhibited a different toxicity profile compared to the Gemcitabine-Cisplatin regimen for palliative chemotherapy in advanced biliary tract carcinoma. While both regimens were generally well-tolerated, the Capecitabine-Cisplatin regimen demonstrated lower incidences of hematological toxicities. These findings emphasize the importance of considering toxicity profiles when selecting treatment options for patients with advanced biliary tract carcinoma.
Study of epidemiology and management of liver abscess in Jammu region
Authors: Iqbal Gulshan Javaid , Faisal Manzoor Shahzada
Published: February 2024

Background: Liver abscess is a common medical condition with different causes and variable morbidity and mortality in different parts of the world, this study has looked into epidemiology, pattern of disease gender and age of affected patients and associated factors.
Methods: This prospective study was conducted at a government medical college over a period of one year from August 2022 up to July 2023. Data of patients managed at our centre was collected, analysed and interpreted on MS Excel.
Results: The majority of affected patients were male (77.5%). 30 to 40 years age group was the most commonly affected, most of the patients presented with complaints of pain abdomen (85%). Amoebic abscess was present in 71.25% of patients. The right lobe of the liver was involved most commonly (67.5%). Conservative management was successful in 56.25% of patients. Alcohol intake was present in 43.75% of patients, complications were pleural effusion, portal vein thrombosis, necrotizing colitis and gastrointestinal bleeding.
Conclusions: In the present era of modern medical science, diagnosis of liver abscesses has become easy through radiological and serological tests, and treatment modalities from minimally invasive to conservative have proved successful in the treatment of liver abscesses. Antibiotics remain the primary course of treatment for both amoebic liver abscess (ALA) and pyogenic liver abscess (PLA), unless there is persistent fever, a substantial abscess cavity, or complications that require surgical intervention. However, challenges persist in combating antibiotic resistance, stemming from incomplete and over-the-counter misuse of available medications. Special concerns include associated comorbidities, delayed medical consultation, and treatment-seeking behavior, as well as the misuse of unhealthy substances or alcohol.
Prevalence of diabetes distress and its psychosocial determinants among Indian population with type II diabetes
Authors: Purushottaman Suraj , Joshi Ameya , Dalal Dhaval , Fahaad Mohd , Rao Namrata , Gore Shivanjali , Vijay Ria
Published: February 2024

Background: Diabetes distress (DD) refers to the negative emotional or affective experience resulting from the challenge of living with the demands of diabetes, regardless of the type of diabetes. In addition to the chronic treatment of diabetes, patients with type 2 diabetes mellitus (T2DM) often experience psychosocial difficulties which can go unnoticed. Hence, it is necessary to identify DD at an early stage to prevent its effect on the patients’ long-term self-care and management plan. This study was conducted to assess the prevalence of DD and its psychosocial determinants among T2DM at a tertiary care centre.
Methods: This was a cross sectional, observational study which included patients of either gender, who were between 18-65 years of age with T2DM for more than 3 months to 12 years. DD was assessed using the diabetes distress scale (DDS17) scale. In addition, association between the level of DD with the sociodemographic and clinical characteristics of the patients was assessed.
Results: The prevalence of DD in type II diabetic patients in suburban population was found to be 17.69%. The psychosocial determinants which influence DD were found to be age, treatment modality, hypothyroidism, hypertension, and smoking.
Conclusions: This study signifies the importance of identifying DD by the primary care physician which often remain unrecognized in clinical practice and to implement the interventions at early stages to improve the quality of life of diabetic patients.