bluuebunny/crossref_metadata_2025 huggingface dataset:
Low plasma adiponectin in risk of type 2 diabetes: observational analysis and one- and two-sample Mendelian randomization analyses in 756,219 individuals
Authors: Nielsen Maria B. , Çolak Yunus , Benn Marianne , Nordestgaard Børge G.
Published: August 2021

We tested the hypothesis
that low plasma adiponectin is observationally and genetic, causally associated
with increased risk of type 2 diabetes. Observational analyses are prone to
confounding and reverse causation, while genetic Mendelian randomization analyses
are much less influenced by these biases. We examined 30,045 Copenhagen individuals observationally (1,751 type 2 diabetes;
plasma adiponectin), 96,903 Copenhagen individuals using one-sample
Mendelian randomization (5,012 type 2 diabetes; five
genetic variants),
and 659,316 Europeans (ADIPOGen, GERA, DIAGRAM, UK
Biobank) using two-sample Mendelian randomization (62,892 type 2 diabetes; ten
genetic variants). Observationally,
and compared to individuals with median plasma adiponectin of 28.9µg/mL(4th
quartile), multivariable adjusted hazard ratios for type 2 diabetes were
1.42(95% CI:1.18-1.72) for 19.2µg/mL(3rd quartile), 2.21(1.84-2.66) for
13.9µg/mL(2nd quartile), and 4.05(3.38-4.86) for 9.2µg/mL(1st quartile).
Corresponding cumulative incidences for type 2 diabetes at age 70 were 3%, 7%, 11%, and
20%, respectively. A 1µg/mL lower
plasma adiponectin conferred a hazard
ratio for type 2 diabetes of 1.07(1.06-1.09), while genetic, causal
risk ratios per 1 unit log-transformed lower plasma adiponectin were
1.13(0.83-1.53) in one-sample
Mendelian randomization and 1.26(1.01-1.57) in two-sample Mendelian
randomization. In conclusion, low plasma
adiponectin is associated with increased risk of type 2 diabetes, an
association that could represent a causal relationship.
ON THE NATURE OF RELATIONSHIPS FOR RECONCILIATION AND THE DESIRABILITY OF THEIR REGULATION IN CIVIL PROCEDURAL CODES
Authors: KAZIKHANOVA S.S.
Published: August 2021

The article analyzes the changes made to the Civil Procedure Code of the Russian Federation, the Arbitration Procedure Code of the Russian Federation and the Administrative Code of the Russian Federation by the Federal Law of 26 July 2019 No. 197-FZ, related to the regulation of conciliation procedures. The question is raised as to whether the civil procedural codes should regulate relations on reconciliation and to what extent. Agreement is expressed with those authors who believe that, by their nature, the relations that develop in conciliation procedures between its participants (including in cases where the conciliation procedure is directed by a judge) are not procedural and are not part of the subject of civil procedural law. The non-procedural nature of the relationship between the judicial conciliator and the court in the procedure of judicial conciliation under the Civil Procedure Code of the Russian Federation, the Arbitration Procedure Code of the Russian Federation and the Administrative code of the Russian Federation is substantiated. It is concluded that due to the qualitatively different nature of reconciliation relations from civil procedural relations, as well as their lack of connection with the resolution of a civil case in a certain system of guarantees (civil procedural form), there is no place for articles on individual conciliation procedures among procedural norms. In this regard, it is proposed to either exclude them, or, as an option, transfer them to the appendix to the Civil Procedure Code of the Russian Federation, the Arbitration Procedure Code of the Russian Federation, the Administrative code of the Russian Federation (just as in the Civil Procedure Code of 1964 there was an appendix, in particular, about the arbitration court).
ALIMONY CLAIMS ACTUAL CAREGIVERS OF THE CHILD: PROCEDURAL FEATURES COURT PERMISSION
Authors: KOMISSAROVA E.G. , KRASNOVA T.V.
Published: August 2021

This article is devoted to theoretical research problems of interaction and correlation material-legal and procedural components in the structure of such a phenomenon as the actual upbringing of a child and the legal consequences that it entails. The “semilegal” regime of this type of relationship, associated with the legislative non-obviousness of their subjects, as well as the criteria for the occurrence of legal consequences of such education, introduces significant features to procedural relations. The authors make one of the few scientific attempts to investigate these features. The subject of theoretical analysis involves essential signs of relationships for the actual upbringing of a child and tools judicial knowledge of this category of cases: logic for the purpose of establishing the content reliability of the studied post-facts, reception reconstruction of past events in the relations of the disputing parties; judicial interpretation, judicial discretion, analogy of the law. In conclusion, the idea is put forward that the problem of proper child-rearing should not be covered by the problem of evaluative concepts. This problem is more of a methodological one, and its effective resolution should start not so much from a protective cross-section of the topic of childhood, where there is room for parental delinquency and the destructive notion of “inappropriate child-rearing” with its extreme cases of infringement of children’s rights and interests, but from a positive-regulative aspect.
Sistem Loker Penitipan Barang Berbasis Mikrokontroler
Authors: Pratama Geri Satria , Elfizon Elfizon
Published: August 2021

Meningkatnya peminat dalam berbelanja di swalayan membuat swalayan harus menyediakan tempat yang aman bagi pembeli untuk barang bawaannya. Dalam hal ini swalayan menyediakan tempat penitipan barang berupa loker dengan keamanan kunci dan sistem yang masih manual. Karena itu masih memakan waktu yang cukup lama dalam mendapatkan kunci loker, bahkan setelah mendapatkan kunci loker kita harus mencari alamat loker berdasarkan kunci tersebut. Tulisan ini bertujuan untuk membuat sistem suatu loker penitipan barang dengan mengunakan RFID sebagai kunci loker untuk mempermudah seseorang dalam menitip barang maupun mencari loker yang kosong. Dan LCD sebagai perintah maupun pemberi informasi loker terbuka secara otomatis. Hasil dari sistem loker penitipan barang sistem microcontroller sudah diuji dan berhasil sesuai perancangan sebelumnya. RFID, LCD dan Relay bekerja dengan baik.
Alat Pendeteksi Kebakaran Menggunakan SMS
Authors: Sari Sindi Permata , Candra Oriza , Asmi Jhefri
Published: August 2021

Lately, there are frequent fires caused by human factors. Because we cannot predict the process of fire in advance. And the delay in knowing the occurrence of a fire is very fatal to the safety of human life and property. With advances in technology, we can overcome fires by making early fire detection devices. With the presence of temperature and smoke detectors, we can detect fires as early as possible and be delivered quickly via alarms and SMS gateways. The main component of this fire detector is the Arduino Uno. This Arduino uno acts as the brain of the fire detection device. This tool works based on the detection of the temperature condition by the DHT11 temperature sensor, which is when the temperature is above normal, an alert notification will be sent via the SMS gateway and so will the MQ2 smoke and the buzzer will sound as a warning alarm.
Sistem MPPT Pengisian Baterai dengan Solar Cell untuk Mobil Listrik
Authors: Septiyan Chris , Taali Taali
Published: August 2021

Solar panel merupakan sumber energi terbaru yang efisien dan ramah lingkungan. Prinsip kerja solar cell yaitu melewati efek fotolistrik dimana bahan-bahan tertentu menciptakan aliran listrik pada cahaya matahari dan menghasilkan arus searah (DC). Sistem pengisian baterai solar cell dengan memanfaatkan cahaya matahari, Watt Peak (WP) adalah satuan yang menyatakan daya produksi tertinggi yang dapat dihasilkan oleh panel surya per satuan waktu. Satuan ukuran panel surya ini didapat dari jumlah produksi daya yang didapat ketika matahari bersinar dengan tingkat radiasi tertinggi. Penyinaran matahari tidak selalu stabil dalam satu hari, matahari mengalami puncak hanya 3 – 5 jam/hari tergantung lokasi. Waktu ideal panel surya menghasilkan daya terbaik (Pmax), yang ditunjukan dalam Wp. Sedangkan untuk menghasilkan daya yang maksimum dibutuhkan pengontrolan tracker panel surya diantara nya maximum power point tracker (MPPT). Dengan menggunakan pengontrolan tracker panel surya yaitu maximum power point tracker (MPPT) maka daya keluaran panel surya akan semakin maksimum.
Sistem Kendali dan Monitoring Boost Converter Berbasis GUI (graphical user interface) Matlab Menggunakan Arduino
Authors: Alfaris Aswaldi , Yuhendri Muldi
Published: August 2021

Artikel ini membahas tentang perancangan sebuah rangkaian converter DC-DC tipe Boost Converter(Penaik tegangan). Rangkaian ini menggunakan GUI (Graphical User Interface) sebagai monitoring. Untuk menaikkan tegangan Boost Converter dilakukan dengan mengatur PWM (Pulsa Width Modulation) menggunakan potensio. Arduino sebagai kontroler penerima respon dari pembacaan sensor. Untuk mengatur besar kecilnya PWM digunakan komponen switching berupa mosfet. Gate drive digunakan sebagai penguat sinyal dan pengaman antara rangkain kontrol dan rangkaian utama. Tegangan masukkan konverter ini adalah 12VDC dengan tegangan keluaran variabel 12VDC-24VDC. Pada rangkaian ini GUI berhasil ditambahkan untuk menampilkan beberapa data dari pembacaan sensor tegangan(Volt) dan sensor arus(Ampere). Hasil dari pembacaan sensor berupa nilai dan grafik ditampilkan pada PC menggunakan software Graphical User Interface (GUI) Matlab.
Sistem Pemesanan Drive Thru Menggunakan Lcd Touchscreen Berbasis Mikrokontroler
Authors: Nur Fatihah Utari , Hastuti Hastuti
Published: August 2021

Pada saat ini belum banyak perusahaan makanan menggunakan proses pemesanan melalui sistem drive thru. Dengan menggunakan sistem drive thru ini maka suatu restoran dapat meningkatkan hasil penjualannya karena lebih memudahkan konsumen dalam memesan makanan. Tugas akhir ini bertujuan untuk membuat dan menguji sistem pemesanan drive thru di restoran menggunakan LCD touchscreen berbasis mikrokontroler. Metode yang digunakan adalah dengan cara merancang, membuat, dan melakukan pengujian hardware dan software untuk bisa diterapkan dalam sistem pemesanan drive thru. Sistem pemesanan drive thru ini menggunakan LCD touchscreen sebagai alat memesan menu pada pemesanan dan juga sebagai tampilan menu yang telah dipesan pada layar koki. Bluetooth HC-05 sebagai penghubung antara pemesanan dengan koki. Untuk pusat kontrol dari sistem pemesanan menggunakan mikrokontroler arduino mega 2560. Hasil dari sistem pemesanan drive thru ini adalah dapat memesan makanan menggunakan LCD touchscreen pada pemesanan dan juga dapat menampilkan pesanan di LCD  koki.
Rancang Bangun Kontrol Pintu Air Dan Monitoring Ketinggian Air Sungai Berbasis Internet of Things (IoT)
Authors: Mahendra Gilang , Sukardi Sukardi
Published: August 2021

Alat pada tugas akhir ini disuplai dengan tegangan 5 VDC digunakan untuk mensuplay tegangan NodeMCU, motor servo dan sensor ultrasonik. NodeMCU digunakan sebagai pusat proses data yang digunakan pada tugas akhir ini, motor servo digunakan untuk membuka dan menutup pintu air. Pada saat supply di hidupkan sensor ultrasonik akan membaca ketinggian air, jika mencapai pada tinggi tertentu maka mikrokontroler NodeMCU akan mengirim status ketinggian serta siaga 1 atau 4 pada  aplikasi android. Pada saat supply di hidupkan sensor ultrasonik akan membaca ketinggian air, jika mencapai pada tinggi tertentu maka mikrokontroler NodeMCU akan mengirim status ketinggian serta siaga 1 atau 4 pada  aplikasi android. Saya membagi menjadi dua kondisi pada penampungan pertama yaitu ketika ketinggian air mencapai 12 cm, motor servo akan membuka 45 dan pintu terbuka setengah serta mengirimkan status Siaga 4 dan kemudian jika air sudah mencapai ambang batas yaitu ketinggian 17 cm motor servo akan membuka pintu 90atau seluruhnya maka air akan mengalir ke penampungan selanjutnya dan mengirimkan notifikasi pada Telegram yaitu Siaga 3.
Penerapan Metode Invers Kinematic pada Rancangan Pergerakan Kaki Robot Humanoid
Authors: Widia Fuji , Risfendra Risfendra
Published: August 2021

Robot humanoid merupakan robot yang memiliki struktur kerangka seperti manusia, memiliki kepala, tangan dan kaki yang dirancang semirip mungkin dengan manusia. Untuk itu, robot ini juga dibuat mampu melakukan pergerakan atau melakukan kegiatan seperti manusia. Robot humanoid merupakan penelitian yang cukup kompleks, banyak metode yang telah diterapkan pada robot humanoid. Salah satunya yaitu metode invers kinematic pada pergerakan kaki robot, invers kinematic dapat menbantu dalam pemodelan gerakan robot sesuai dengan yang dibutuhkan. Dimana invers kinematic merupakan metode analisa untuk menentukan besar sudut pada setiap joint dengan tujuan dan end-effector sudah diketahui. Untuk menerapkan metode ini terdapat ketentuan-ketentuan yang berlaku yang harus diikuti untuk membentu keberhasilan penerapan metode ini pada pergerakan kaki robot humanoid. Analisa ini dibuat berdasarkan pola susunan aktuator pada robot, serta panjang antar joint dan panjang keseluruhannya pada kaki robot humanoid, juga menentukan arah putaran setiap joint pada sudut-sudut yang telah dirancang. Robot ini menggunakan dynamixel servo sebagai aktuator dengan pemasangan kerangkan mengikuti pola susunan Robotis Bioloid tipe A dan OpenCM-9.04 sebagai controller. Dari hasil pengujian robot dapat bergerak sesuai rancangan pergerakan dan ketentuan arah putaran servo yang telah dirancang, dengan menghasilkan tiga tahapan gerakan yang diinisialisasikan dengan tegak, melangkah dan maju. Titik koordinat pada kaki kanan dengan posisi tegak (0.0, 0.0, 0.0), melangkah (20.0, 10.0, 20.0), maju (20.0, 10.0, 20.0), sedangkan pada kaki kiri posisi tegak (0.0, 0.0, 0.0), melangkah (30.0, 15.0, 20.0) dan maju (30.0, 15.0, 20.0).
Perancangan Vending Machine Menggunakan Uang Kertas Berbasis Arduino
Authors: Alkausar Vicky Mora , Husnaini Irma
Published: August 2021

Pesatnya perkembangan teknologi pada saat ini sangat memudahkan perekonomian masyarakat khususnya dalam hal jual-beli. Kemudahan dalam melakukan jual-beli salah satu kunci untuk meningkatkan efektifitas dalam meningkatkan pendapatan bagi masyarakat.  Vending  machine  adalah salah satu alat yang dibutuhkan untuk membantu memudahkan perekonomian bagi masyarakat dalam hal jual-beli. Tulisan ini bertujuan merancang sebuah vending  machine yang bekerja berdasarkan pendeteksian uang yang dimasukkan . Alat ini menggunakan TCS 3200-DB sebagai sensor untuk mendeteksi uang dan menggunakan arduino sebagai pusat kontrol serta pemroses data. Pada saat uang sudah terbaca oleh sensor TCS 3200-DB, maka LCD akan menampilkan nominal uang yang masuk. Setelah jumlah uang mencapai total Rp. 5000,- maka servo akan aktif dengan membuka katup besi yang di rancang khusus untuk mengeluarkan minuman yang sudah di pilih. Hasil pengujian  alat  Vending  Machine   ini   menujukkan bahwa alat ini sudah bekerja sesuai dengan rancangan yang diinginkan, dimana alat bekerja dengan baik dan mampu mengenali uang kertas Rp. 1000, 2000 dan 5000,- dengan tingkat keberhasilan 86.6%.
Implementasi MPPT Panel Surya Berbasis Algoritma Perturbasi & Observasi (PO) Menggunakan Arduino
Authors: Masrepol Haris , Yuhendri Muldi
Published: August 2021

Solar panels are a renewable energy power plant that uses sunlight as its main energy source. The power generated by solar panels are determined by the size of the solar panels, solar radiation and temperature. The power of the solar panels is also determined by the output voltage of the solar panels. To get the maximum output power at any time, it is necessary to adjust the output voltage of the solar panel. This study proposes controlling the maximum output power of solar panels, also known as maximum power point tracking (MPPT) by adjusting the output voltage of the solar panels using a buck converter. The buck converter output voltage regulation at the maximum power point of the solar panel is designed with the Perturbation and Observation (PO) algorithm which is implemented using an Arduino Mega 2560. This MPPT control system is applied to 4x50 Watt-Peak (WP) solar panels which are connected in parallel. The experimental results show that the proposed MPPT control system with the PO algorithm has worked well as expected. This can be seen from the output power generated by the solar panels already around the maximum power point at any change in solar radiation and temperature.
Parâmetros para determinar o comprimento dos dentes anteriores superiores em pacientes edêntulos
Authors: Floriani Franciele , Sabatini Gabriela Panca , Oliveira Tarla , Badaró Mauricio , Philippi Analucia Gebler , Mezzomo Luis André
Published: August 2021

This article describes the main aspects that must be observed during the determination of the length of the upper anterior teeth.
Como realizar a análise tridimensional das vias aéreas superiores em pacientes ortodônticos?
Authors: Barreto Luísa Schubach da Costa , das Neves Bruno Moreira , Quintão Cátia Cardoso Abdo , Miguel José Augusto Mendes
Published: August 2021

The upper airways (UA) are influenced by the growth and development of the craniofacial complex and any alteration in the maxillary bones during orthodontic treatment can narrow or increase the size of the pharyngeal spaces. The three-dimensional analysis of the volume and the minimum axial area of the respective sub-spaces is beneficial for case planning as it allows the identification of possible physical barriers that compromise the air passage and the respiratory flow, besides being an auxiliary diagnostic method for disorders related to this function. The request for cone-beam computed tomography (CBCT) is necessary for the correct digital evaluation with the appropriate protocols for the acquisition and reconstruction of the image exams, calibration of the methodology, and standardization of their analysis. The objective of this work is to demystify the specific step-by-step analysis in the Dolphin Imaging® software and to describe the technical and anatomical factors for delimiting the spaces corresponding to the UA. To illustrate this protocol, CBCT of a patient with Angle Class II malocclusion, first division were analyzed before the installation (T1) of a mandibular thruster (fixed cemented Herbst appliance with dental anchorage) and after 12 months of treatment (T2). From the measurement of the spaces corresponding to VAS, comparing the two treatment times, it was possible to analyze the changes in the pharyngeal space after the use of mandibular thruster and to highlight the importance of the three-dimensional assessment of the air dimension for individualized orthodontic planning.
Electric Energy Potential from Pineapples and Potatoes
Authors: Syahirah Atikah Nur , Cahyati Riska
Published: August 2021

Basically, the voltage can be obtained from various sources, including fruit. Fruit is often used as food, drink and a source of vitamins for the body's defense system. It turns out that it has the ability to generate electricity, especially for fruit that has a high acidity level. The acidity in some types of fruit is able to generate electricity because it is electrolyte. Fruits which contain mineral acids in the form of hydrochloric acid and citric acid, are strong electrolytes that break down completely into ions in a water solution. Besides having acid, fruits also contain a lot of water, so that when two different metals are immersed, the fruit solution will create a potential difference between the metal and water so that there is an electrode potential that can generate electric current as well. The purpose of making a rough draft of this practicum is to prove the existence of electrical energy in pineapples and potatoes. In this experiment, it has been proven that pineapples and potatoes can produce an electric current, indicated by the presence of a voltage when measured by a voltmeter.
Innovative development of transport sphere: economic, marketing, educational aspects
Authors: Stovba Tetyana , Zhuk Tetiana , Tsercovna Alona , Slatvinska Valeria
Published: August 2021

The purpose of the research is to study the components and problems inhibiting the development of the interrelationship of economic, marketing, educational aspects in the innovative development of the transport sector. The methodological base is as follows: methods of sociological analysis and conducting surveys on the “Typeform” platform, methods of bibliometric and patent analysis, which are based on search platforms Web of Science and Derwent Innovation. 1000 economists, marketing experts, teachers, and students took part in the survey (Ukraine). It has been determined that the economic aspects consist of the creation and development of a full-fledged international transport and logistics center; a network formation of transportation and logistics hubs; development of multimodal transportation, introduction of modern information and control systems, renewal of the vehicle fleet, incentives towards creation of large local freight forwarders. The problematic issues of the sector have been outlined. It has been found out that the principal directions of innovative development are integration of machine-building and information technologies into transportation tools and infrastructure, etc.
The Issues and Challenges Faced by Malay Cuisine in the Foreign Market
Authors: Abdullah Rahman , Arifin Aniza , Samsudin Azlina , Bachok Sabaianah , Zahari Harnizam
Published: August 2021

The traditional food of a culture in a society is continuously inherited from the old generation to the new generation. The traditional element is an in-depth understanding of the function of each material, techniques of preparation, and the practice in our daily cooking. This understanding in the form of preparation, meal preparation, tips, use of certain equipment, and raw materials are mysteries difficult to be unravelled. The Malay cultural heritage food is an integral asset among Malaysians in general and the Malay race in particular. Malay cuisine is one of the special and unique blended of many traditions from around the region. However, when Malay culture and cuisine are introduced to other countries, they faced certain hurdles and challenges. This study investigates the issues and challenges faced by Malay cuisine in the foreign market. The points in question are, 1) Why are Malay cuisine difficult to be exported to other countries 2) Why Malay cuisine is less popular than cuisines from other countries? 3) What are the factors that make foods from a country of origin can be successfully exported? These issues and challenges will be parsed and discussed based on the existing written collection. Recommendations will be made on the mechanisms that enable the success of Malay cuisine food to be commercialized abroad, as well as future research examining the success factors of traditional food exported abroad.
Attitudes Analyses of Mobility Disorders Adolescentsâ€™ Parents in Regards of Improvement Social and Household Skills
Authors: Ghazaryan Tatevik
Published: August 2021

The purpose of this study is to analyse the attitudes of parents of adolescents with mobility disorders regarding the need to improve their children's social and household skills.
The methodology of data collection, processing and analysis of the research is based on the approach of quantitative methods, which allows combining the collection of quantitative data, using quantitative methods, later having the opportunity to conclude the data obtained through certain numerical patterns. The specially designed questionnaire was administered to 125 parents of adolescents with mobility disorders.
The survey showed that the vast majority of parents consider their children's independent life as a priority. The need to teach their children social and household skills such as shopping, cooking, cleaning kitchen utensils and the area, helping with household chores is also mentioned as quite important.
At the same time, the insufficient awareness of parents about the idea of living an independent life, the inconsistency of adolescents' ability to carry out household activities, the inconsistency between their subjective perceptions, as well as the overprotection possibility of one of the traditional Armenian cultural features should be mentioned too.
Factors Affecting the Efficacy of Aphasia Rehabilitation
Authors: Paylozyan Zhanna
Published: August 2021

This paper aims to test the influence of premorbid verbal intelligence on the nature of aphasia and spontaneous speech recovery and to study the role of a micro-social environment on the effectiveness of speech rehabilitation.
The quantitative and qualitative methods of analyses as well as special parameters to determine characteristics of the communicative-speech environment and the degree of its influence on the process of speech recovery were selected.
A total of 65 patients with aphasia have been selected to study the effect of multilingualism on the efficacy of speech therapy. Family members of 150 patients with aphasia were interviewed to find out the micro-social environment effects on the process of aphasia rehabilitation and to inquire about a correlation between the degrees of involvement of the patient's environment in the process of speech therapy.
The factor of multilingualism and factor of the communicative-speech environment are interrelated with each other and the choice and appropriate use of language by the patients with aphasia need to be controlled from the outside.
The Analyses of Possible Indicators of Children With Autism Spectrum Disorders Early Diagnosis
Authors: Kharatyan Kristina
Published: August 2021

Nowadays autism spectrum disorders (ASD) are on the list of most frequent childish disorders. It is characterized by communicational, behavioural, and emotional difficulties, unique manifestations of cognitive processes, lack of communicational initiative. ASD is a developmental disorder that occurs in early childhood, persists into adulthood, and affects three areas of development: communication, social partnership, and behavior.
So, when the means of communication are incomplete or absent, the normal course of the child's development is being disrupted, social adaptation becomes impossible. For the effective organization of speech therapy intervention of children, it is necessary to start child`s rehabilitation work as   possible of the child's development:
The author's long time professional experience (15 years) in working with these children indicates that one of the keys to the best effectiveness of communication and speech development is early intervention, which can be organized only after the early detection and diagnosis of children with ASD.
One of the prerequisites for early diagnosis is to ensure the continuity of the awareness process among parents, which is the main goal of our article.
Parents Experience in Giving Sex Education to Adolescents in North Kuta
Authors: Sanjiwani Ida Arimurti , Pramitaresthi I Gusti Ayu
Published: August 2021

Sexual education is an important think that parents can do to prevent free sex and it effects in adolescent. It is possible because family is the first place of education, but it appears to be inadequately practiced in Indonesia. This study aims to determine parent experience to provide sexual education in adolescents. We used a phenomenology interpretative approach in this study. We collected the data through in-depth interviews with ten parents. We found five themes: (1) good perception about sexual education, (2) sexual education delivered assisted by social media, (3) the topic is free sex, (4) difficult to start because of taboo and shame, (5) need support from health worker. The study reveals that sexual education is limited and need to be increased. It is essential that Indonesian parents become better informed and skilled, so that they may be involved in the sexual education of adolescent start from their family.

Index Terms— sexual education, adolescent, parents experience
Faktor-Faktor yang Memengaruhi Kompetensi Penyuluh Narkoba dalam Penyuluhan Digital
Authors: Rizal Afib , Fatchiya Anna , Sadono Dwi
Published: August 2021

Utilization of digital media for an extension is a solution the improvement of the competence of Anti-Narcotics extension agents. This study aims to analyze the influence of the individual characteristics of the extension agents, patterns of digital media use, institutional support, and characteristics of innovation on the competence of Anti-Narcotics extension agents. This research was conducted in October 2020 - January 2021 through a census of 170 (98%) functional officers of Anti-Narcotics extension agents throughout Indonesia who have worked for approximately two years. The research instruments were questions, statements (telephone and message), and interviews which were conducted using the digital application Google Form and WhatsApp. Data were processed using Partial Least Square. The results showed that the use of digital media by extension agents consisting of patterns of digital media use, characteristics of innovation, institutional support, and competence of Anti-Narcotics extension agents in the field of information and communication technology were in the Medium category. The competence of Anti-Narcotics extension agents in the use of digital media  was in the medium category. This competence is influenced by factors of digital media utilization patterns, innovation characteristics, and institutional support.
Implementasi Penyuluhan Hortikultura Berkelanjutan di Provinsi D.I. Yogyakarta
Authors: Euriga Epsi , Amanah Siti , Fatchiya Anna , Asngari Pang S
Published: August 2021

Sesuai amanah Undang-Undang No.16 Tahun 2006 tentang Sistem Penyuluhan Pertanian, Perikanan dan Kehutanan, implementasi penyuluhan mulai memfokuskan pada aspek keberlanjutan yaitu meningkatkan kesadaran dalam pelestarian fungsi lingkungan hidup. Hortikultura berkelanjutan merupakan salah satu inovasi dalam melaksanakan pertanian tanpa merusak lingkungan. Adopsi hortikultura berkelanjutan belum sepenuhnya dilaksanakan oleh petani hortikultura di Provinsi Daerah Istimewa Yogyakarta (DIY) meskipun telah dilaksanakan penyuluhan. Penelitian sebelumnya menyebutkan bahwa salah satu faktor yang mempengaruhi suatu adopsi adalah penyuluhan. Penelitian ini bertujuan untuk menganalisis efisiensi implementasi penyuluhan hortikultura berkelanjutan di Provinsi DIY. Survey dilakukan pada 350 petani hortikultura di Kabupaten Sleman, Kulonprogo dan Bantul, Provinsi DIY. Hasil survey menunjukkan bahwa efisiensi implementasi penyuluhan di DIY berada dalam kategori tinggi, yaitu: materi penyuluhan, metode penyuluhan dan kompetensi penyuluh pada kategori tinggi, sedangkan keterlibatan petani pada kategori sedang. Materi penyuluhan perlu diperkuat dalam hal penggunaan mulsa dan pemasaran dengan mempertimbangkan aspek kelayakan lingkungan dan ekonomi. Metode penyuluhan ditingkatkan dengan pelatihan (training) dan sekolah lapang. Penyuluh harus berkompetensi mengajak petani agar mengurangi penggunaan bahan kimia dalam memberantas hama dan gulma. Untuk meningkatkan partisipasi petani penyuluh harus meningkatkan frekuensi pertemuan dengan petani.
The visionary who transformed private health care in India
Authors: Vaishya Raju
Published: August 2021

Dr. Prathap Chandra Reddy is the Founder-Chairman of the Apollo Hospitals Group (AHG) and is considered a living legend and architect of modern private health care in India. In 1983, Dr. Reddy started the first professionally run private hospital – Apollo Hospitals in Madras (now Chennai). Since then, the AHG has expanded to over 73 hospitals across the country. The state-of-the-art facilities have made advanced health-care services accessible and affordable to all in need. AHG has a presence in primary care, secondary care, tertiary care, quarterly care, health IT, tele-health (tele-consults, tele-pathology, tele-cardiology, and tele-radiology), eICU pharmacy retailing, project consultancy, research, and academics. He catalyzed a “reverse brain drain” by inspiring hundreds of Non-Resident Indian Doctors to come back to India, by creating opportunities and providing them with a world class medical ecosystem. Dr. Reddy’s contributions are widely recognized by patients, doctors, the health-care fraternity across the world, the community at large, and by the Government of India.
Optimizing international neurosurgical outreach missions: 15-year appraisal of operative skill transfer in Lima, Peru
Authors: Jandial Rahul , Narang Pranay , Brun Jorge Daniel , Levy Michael L.
Published: August 2021

Background:

While several medical outreach models have been designed and executed to alleviate the unmet need for international neurosurgical care, disparate strategies have evolved. There is a need to determine the optimal pediatric neurosurgical outreach model through which resources are efficiently utilized while imparting the largest possible impact on global health. This study evaluates the efficacy of an international pediatric neurosurgery outreach model at transferring operative skill in a sustainable and scalable manner in Lima, Peru over a 15-year duration.

Methods:

Three 1-week neurosurgical missions were carried out (2004–2006) in Lima, Peru to teach neuroendoscopic techniques and to provide equipment to host neurosurgeons, equipping the hosts to provide care to indigent citizens beyond the duration of the missions. Follow-up data were obtained over a 15 year span, with collaboration maintained over email, two in-person visits, and video-conferencing services.

Results:

Since the outreach missions in 2004–2006, the host neurosurgeons demonstrated sustainability of the neuroendoscopic instruction by independently performing neuroendoscopic operations on a growing caseload: at baseline, 0 cases were performed in 2003, but since 2012 and onwards, 40–45 cases have been performed annually. Scalability is illustrated by the fact that the institution established a rigorous neuroendoscopy training program to independently pass on the techniques to resident physicians.

Conclusion:

The described international pediatric neurosurgical outreach model, centered around teaching operative technique as opposed to solely providing care to citizens, allowed operative skill to be sustainably transferred to surgeons in Lima, Peru. Having served the neuroendoscopic needs of hundreds of citizens, the strategic design is replicable and should be mirrored by future medical endeavors seeking to substantially impact the deficit in global surgical care.
ANALYSIS OF THE DIGITAL ECONOMY AND SOCIETY INDEX (DESI) THROUGH A CLUSTER ANALYSIS
Authors: SEVGİ Hüseyin
Published: August 2021

OBJECTIVE: This study has two main goals. The first one aims to determine how the European Union countries are clustered according to The Digital Economy and Society Index (DESI) 2020 data. The second one aims to determine whether there is a similarity between the DESI cluster of the European Union countries and the social welfare regime classification. METHODS: In the research, the cluster method was used in accordance with DESI 2020 data. RESULTS: Technological and digital investments and initiatives of countries have clustered the European Union countries in 4 different groups. The countries clustered according to DESI data are shaped for investments and spending for digitalization within the scope of sub-dimensions of DESI. In this context, the welfare regimes applied by the countries affect the spending for digitalization. CONCLUSIONS: According to The Digital Economy and Society Index (DESI) 2020 data has proved that there is a similarity between the classification of the European Union countries according to their welfare regimes and digitalization.
ÖZÜMSEME KAPASİTESİNİN İŞLETME PERFORMANSI ÜZERİNE ETKİSİ: KOBİ’LERDE BİR ARAŞTIRMA
Authors: KAPLAN Mehmet
Published: August 2021

Özümseme kapasitesi işletmelerin yeni bir bilginin değerinin farkına varabilmesi, onu özümseyip işletme amaçlarına yönlendirebilmesini ifade etmektedir. İşletmelerin yeni bilgiyi kavramasını, özümsemesini ve kullanmasını sağlayan özümseme kapasitesi işletmenin performansı üzerinde etkili bir unsur olarak değerlendirilmektedir. Bu noktada bu çalışmada “işletmelerin özümseme kapasitelerinin işletme performansı üzerinde etkisi var mıdır?” temel araştırma sorusuna yanıt aranmaktadır. Çalışma, Isparta-Burdur Bölgesi KOBİ’lerinde gerçekleştirilmiştir. İlgili KOBİ’lerde yönetici düzeyinde çalışan 218 kişiye ulaşılmıştır. İlgili kişilere yönelik anket tekniği kullanılmıştır. Yazında bu yöndeki çalışmalar daha çok büyük işletmelerde gerçekleştirilmiş dolayısıyla üretilen sonuçlar ve öneriler de bu yönde değer bulmuştur. Ancak bu çalışma KOBİ’lerde gerçekleşmesi dolayısıyla yazına özgün bir değer katabilir ve pratik uygulamaya yönelik yararlı fikriler sunacağı düşünülmektedir.
Elevated glucose increases genomic instability by inhibiting nucleotide excision repair
Authors: Ciminera Alexandra K , Shuck Sarah C , Termini John
Published: August 2021

We investigated potential mechanisms by which elevated glucose may promote genomic instability. Gene expression studies, protein measurements, mass spectroscopic analyses, and functional assays revealed that elevated glucose inhibited the nucleotide excision repair (NER) pathway, promoted DNA strand breaks, and increased levels of the DNA glycation adduct N2-(1-carboxyethyl)-2ʹ-deoxyguanosine (CEdG). Glycation stress in NER-competent cells yielded single-strand breaks accompanied by ATR activation, γH2AX induction, and enhanced non-homologous end-joining and homology-directed repair. In NER-deficient cells, glycation stress activated ATM/ATR/H2AX, consistent with double-strand break formation. Elevated glucose inhibited DNA repair by attenuating hypoxia-inducible factor-1α–mediated transcription of NER genes via enhanced 2-ketoglutarate–dependent prolyl hydroxylase (PHD) activity. PHD inhibition enhanced transcription of NER genes and facilitated CEdG repair. These results are consistent with a role for hyperglycemia in promoting genomic instability as a potential mechanism for increasing cancer risk in metabolic disease. Because of the pleiotropic functions of many NER genes beyond DNA repair, these results may have broader implications for cellular pathophysiology.
Application Strategy of Mechatronics in Mechanical Design and Manufacturing
Authors: Lin Zhe , Fang Rongqing
Published: August 2021

Industry is an pillar sector for our country's social and economic development. The development of industry is closely related to our country's economic development and social construction. The application of mechatronics in mechanical design and manufacturing can not only improve the level of mechanical design and manufacturing as well as production efficiency, but also can contribute to the further development of the mechanical design and manufacturing industry. The author investigated and analyzed advantages of the mechatronics’s application in mechanical design and manufacturing, and put forward an effective strategy of applying mechatronics in mechanical design and manufacturing, hoping to help strengthen the comprehensive strength of the mechanical design and manufacturing industry.
Overview on the Blockchain-Based Supply Chain Systematics and Their Scalability Tools
Authors: Hellani Houssein , Sliman Layth , Samhat Abed Ellatif , Exposito Ernesto
Published: August 2021

Modern IT technologies shaped the shift in economic models with many advantages on cost, optimization, and time to market. This economic shift has increased the need for transparency and traceability in supply chain platforms to achieve trust among partners. Distributed ledger technology (DLT) is proposed to enable supply chains systems with trust requirements. In this paper, we investigate the existing DLT-based supply chain projects to show their technical part and limitations and extract the tools and techniques used to avoid the DLT scalability issue. We then set the requirements for a typical DLT-based supply chain in this context. The analyses are based on the scalability metrics such as computing, data storage, and transaction fees that fit the typical supply chain system. This paper highlights the effects of Blockchain techniques on scalability and their incorporation in supply chains systems. It also presents other existing solutions that can be applied to the supply chain. The investigation shows the necessity of having such tools in supply chains and developing them to achieve an efficient and scalable system. The paper calls for further scalability enhancements throughout introducing new tools and/or reutilize the current ones. Doi: 10.28991/esj-2021-SP1-04 Full Text: PDF
The effect of cigarette smoking on serum levels of regulatory cytokines and molecules involved in atherogenesis during systemic treatment of psoriasis – results of a preliminary study
Authors: Zdanowska Natalia , Owczarczyk-Saczonek Agnieszka B. , Czerwińska Joanna , Nowakowski Jacek J. , Kozera-Żywczyk Anna , Owczarek Witold , Zdanowski Wojciech T. , Swacha Zbigniew , Placek Waldemar
Published: August 2021

Introduction:
Among the diseases associated with psoriasis linked to smoking are primarily cardiovascular diseases (including atherosclerosis) and metabolic syndrome. In addition, cigarette smoking also affects the effectiveness of systemic treatment of psoriasis.

Aim:
Assessment of the effect of cigarette smoking on biomarkers of atherosclerosis in patients with psoriasis treated with methotrexate and adalimumab.

Material and methods:
The serum levels of vascular cell adhesion molecule 1 (VCAM-1), E-selectin, oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibodies, IL-10, IL-35, TGFß1, were assessed in 34 patients with psoriasis (15 smokers and 19 non-smokers), and 8 healthy, non-smoking volunteers.

Results and discussion:
Smoking patients had significantly higher body mass index, lower high density lipoprotein (HDL), higher risk of 10-year fatal cardiovascular disease, higher IL-10 levels and lower IL-35 levels at baseline compared to healthy, non-smoking volunteers. We observed decreases in IL-10, VCAM-1, E-selectin, and oxLDL levels during 12 weeks of methotrexate treatment and, a decrease in IL-35 during adalimumab treatment, based on enzyme-linked immunosorbent assays.

Conclusions:
Our results indicate the need for a holistic approach to psoriasis treatment that includes lifestyle modifications like smoking cessation to slow the development of atherosclerosis and increase the possibility of improving skin lesions.
Pengaruh Komposisi Ekstrak Mengkudu (Morinda citrifilia L.) Sebagai Antibakteri Pada Shampo Herbal Berbasis Methyl Ester Sulfonat (MES)
Authors: Dara Syafira , Suryati Suryati , Meriatna Meriatna , ZA Nasrul
Published: August 2021

Shampoo is a preparation that contains surfactants in a suitable form and is useful for removing dirt and grease attached to the hair and scalp so as not to harm the hair and scalp. In this study the ingredients used were noni fruit extracts and surfactants using Methyl Ester Sulfonate (MES). The purpose of this study was to analyze the effect of time when making herbal shampoo, the effect of adding noni fruit extract to the quality of shampoo. To obtain the noni fruit extract maceration process is used by using distilled water. Noni ripe fruit is cut and then blended and then added 2 liters of aquadest, evaporated in a rotary evaporator. The processing of herbal shampoo is done by the influence of the volume of noni fruit extract and time by comparison: 5 ml: (1,2,3,4) minutes, 10 ml: (1,2,3,4) minutes, 15 ml: (1, 2,3,4) minutes, 20 ml (1,2,3,4) minutes. Tests carried out pH testing, foam stability test (%), foam height test (cm), viscosity (cps) and anti-bacterial test (colony, cm2). Based on the research results obtained high foam with 88 mm, foam stability 92.04%, Viscosity 2.31, antibacterial 31.7 colonies / cm2, and pH 4.2. The research results are expected to meet Indonesian National Standards.
Studi akurasi model pembakaran pada terhadap prediksi temperatur pada nyala metana tak pracampur menggunakan CFD
Authors: Tobing Rido Lumban , Wusnah Wusnah , Sylvia Novi , Azhari Azhari , ZA Nasrul
Published: August 2021

Tidak dapat dipungkiri bahwa pembakaran telah mendorong kamajuan dunia ekonomi dan masyarakat sejak manusia menggunakan api. Selain memberikan manfaat bagi manusia, pembakaran juga menghasilkan kerugian dalam hal emisi gas yang dapat merusak lingkungan.Berbagai upaya telah dilakukan untuk meningkatkan efisiensi pembakaran. Computational Fluid Dynamics( CFD) memainkan peranan penting dan digunakan sebagai alat standar di sebagian besar perusahaan dan industri konsultan. Penelitian ini bertujuan untuk menyelidiki kinerja model pembakaran untuk memprediksi temperatur pada nyala metana menggunakan metode Computational Fluid Dynamics (CFD) dengan beberapa model pembakaran yang tersedia pada Ansys Fluent 2020 R1 yaitu Eddy Dissipation Concept dan Non Premixed Combustion. Hasil dari penelitian ini membuktikan bahwa model pembakaran Eddy Dissipation Concept merupakan model yang terbaik dibandingkan dengan model Non Premixed Combustion.secara kualitatif temperatur model Eddy dissipation Concept yang mendekati nilai data eksperimen, dimana suhu yang dicapai model Eddy dissipation Concept mencapai 1840 K pada posisi sekitar 700 mm atau 0.7 m. Secara kuantitatif model Non premixed Combustion tren grafiknya mengikuti data eksperimen namun puncak tertingginya hanya mencapai 1452 K pada posisi sekitar 540 atau 0.54 m di atas nozzle, sedangkan data eksperimen suhunya mencapai 1816 K pada posisi sekitar 560 mm atau 0.56 m.peneliti berharap hasil dari penelitian ini dapat menjadi masukan kedepannya dalam mensimulasikan pembakaran nyala tak pracampur pada metode Computational Fluid Dynamics (CFD).
PEMANFAATAN MINYAK NILAM ACEH UTARA SEBAGAI FIXATIF AGENT DALAM PEMBUATAN PENGHARUM RUANGAN BERBASIS CAIR
Authors: Sitanggang Evi Dahliani , Jalaluddin Jalaluddin , Ginting Zainuddin
Published: August 2021

Tanaman nilam (Pogostemon cablin Benth) merupakan salah satu tanaman penghasil minyak atsiri yang cukup penting sebagai komoditi ekspor Indonesia. Industri minyak nilam Aceh, yaitu di wilayah Lhokseumawe-Aceh Utara mulai berkembang sejak tahun 1996, dan diketahui nilam Aceh Utara merupakan varietas tanaman nilam terbaik kedua di dunia dengan kandungan patchouli alcohol 34,46 %. Tujuan penelitian adalah untuk mendapatkan hasil pengaruh minyak nilam terhadap produk pengharum ruangan dan untuk mendapatkan formulasi yang menghasilkan tingkat keharuman yang lebih kuat dan tahan lama. Adapun bahan yang digunakan dalam penelitian ini adalah minyak nilam Aceh Utara, Etanol 76 %, Bibit pewangi, dan Propilen glikol, kemudian dilakukan pencampuran bahan-bahan dengan cara dihomogenisasikan manual selama 1-2 menit. Hasil penelitian menunjukan dalam uji organoleptik formulasi pengharum ruangan dalam minyak nilam pada volume 0,15 ml, 0,25 ml dan 0,4 ml didapat hasil yang terbaik pada volume minyak nilam 0,25 ml. Hasil pengharum ruangan yang didapatkan sangat wangi dan beraroma khas kopi dan wangi nilam yang lembut. Volume 0,25 ml digunakan untuk sebagai pengujian di variabel terikat. Dari hasil analisis statistik menunjukkan bahwa pengharum ruangan yang banyak disukai panelis ada pada pengharum ocean fresh dan terdapat formulasi pertama dan ke enamlah yang dianggap paling harum dengan perbandingan zat pewangi (kopi): pelarut sebanyak 3 ml:2 ml. Dalam Uji ketahanan Wangi hasil menunjukan pada formulasi keempat yaitu formulasi perbandingan zat pewangi 4 ml dan pelarut 2 ml yang dipengaruhi oleh bobot/berapa panjangnya sisa zat cair. Dalam uji penyerapan zat cair hasil menunjukan yang lebih cepat menguap dan habis ada pada formulasi ketiga yaitu zat pewangi (kopi): pelarut sebanyak 3 ml:3 ml. Hasil penguapan zat cair menunjukan total terbesar persen penguapan dihasilkan pada ruangan yang diberi kipas angin.