bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation and evaluation of a pre-assessment telephone triage system in an outpatient photopheresis service
Authors: Rushton Cherie , Robertson Leeah , Taylor Tracie , Taylor Peter , Alfred Arun
Published: April 2017

The prompt assessment of patients as fit for photopheresis is imperative to ensure delivery of a safe and efficient service. Before January 2015 the photopheresis unit was reliant on patients contacting the department directly to cancel their appointment if they were unwell or were suffering from any pre-defined exclusion criteria. Methods to reduce the number of cancellations and patients arriving unwell were therefore examined. The authors combined aspects of patient pre-assessment with telephone triage to develop a system that could provide better care and improve the use of resources within the department. The pre-assessment telephone triage system successfully reduced cancellations and increased patient awareness of conditions that would prevent delivery of photopheresis treatment. Subsequently the quality improvement initiative established that the pre-assessment telephone triage system saved the photopheresis unit over £33 000 over a 12-month period.
Student nurse mentoring: an evaluative study of the mentor's perspective
Authors: Rylance Rebecca , Barrett Julie , Sixsmith Pam , Ward Donna
Published: April 2017

An evaluative study aimed to capture the ‘mentor voice’ and provide an insight into the mentoring role from the perspective of the nurse mentor. Participants from each of the four fields of nursing practice were asked to comment on the satisfying and frustrating aspects of their mentoring role. The narrative data gleaned from the evaluation were qualitatively analysed and subsequently organised into key themes around the student–mentor relationship and the clinical environment. Given that the landscape of nurse education is set to change, in terms of new standards from the professional bodies and the political drivers, not to mention the changing profile of the student nurse, it is hoped that the findings may help to shape the relationship between the mentor, the student and the higher education institution.
Critical care nurses' knowledge and practice of delirium assessment
Authors: Rowley-Conwy Gabby
Published: April 2017

Aims:

The aim of this study was to examine perceived barriers to assessment of delirium for critical care nurses, and the impact of education on their knowledge and practice.

Background:

Delirium is a significant problem in critical care, leading to increased morbidity and mortality. Many authors have found variations in assessment by critical care nurses, but there has been limited analysis of the reasons for this. Education on the topic improves knowledge and practice, but the best approach has not been examined.

Design:

A questionnaire survey design.

Methods:

A self-reported questionnaire was distributed to critical care nurses (n=31) at a district general hospital. Data were analysed with descriptive statistics.

Results:

Knowledge and practice were variable, but correlation was seen between nursing band and years of experience with better scores. Any type of education led to significantly improved scores. Several barriers to assessment were found, with the most common being lack of knowledge and difficulty in assessing intubated patients.

Conclusion:

It is essential to improve practice in delirium assessment and management. Education is vital to improve the knowledge and practice of critical care nurses regarding delirium.
Meeting the healthcare needs of adults on the autism spectrum
Authors: Barber Christopher
Published: April 2017

People with Asperger's syndrome/high functioning autism (AS/HFA) are just as likely to experience the full range of health conditions and needs as ‘neurotypicals’, people who do not have AS/HFA. However, many people with AS/HFA fall between the cracks of health service design and provision as they do not receive support from learning disabilities or mental health services. This article highlights the need for a comprehensive review of healthcare provision, led by people on the autism spectrum.
The State of Care report: patient safety in NHS acute hospitals
Authors: Tingle John
Published: April 2017

John Tingle, Reader in Health Law at Nottingham Trent University, discusses the Care Quality Commission's recently published report on the quality of hospital care in England
Demystifying research: it's for everyone
Authors: Foster Sam
Published: April 2017

Sam Foster, Chief Nurse at Heart of England NHS Foundation Trust, explains how practical guidance is now available to help all nurses—including those starting their careers on the frontline—to contribute to research
HPV: why it's time to start vaccinating boys
Authors: Peate Ian
Published: April 2017

Is only immunising half the country against HPV a mistake? Ian Peate argues for male vaccinations too
Allergic rhinitis: waving goodbye to the allergic salute
Authors: Greener Mark
Published: April 2017

Mark Greener unpicks the more-than-minor irritant behind everything from itchy noses to ruined sleep
Enhancing care for patients with sciatica: A case report
Authors: Thompson Alexander
Published: April 2017

This article uses a case study to provide an example of how an advanced practice physiotherapist uses prescribing skills to improve the pathway and experience of patients with sciatica. The process of examination, reasoning and diagnosis is described. Management strategies are discussed, including the use of neuropathic pain medication for sciatica. The evidence for this management approach is analysed. The legal and ethical considerations regarding non-medical and specifically physiotherapy prescribing are also addressed. The use of prescribing by the advanced practice physiotherapist following accurate diagnosis allowed the patient to gain access to appropriate medication, facilitating a seamless pathway, supporting rehabilitation and resulting in resolution of the condition. This case report demonstrates that an advanced practice physiotherapist with the ability to independently prescribe leads to an improved seamless pathway for patients.
The treatment of metastatic prostate cancer
Authors: Meade Elizabeth
Published: April 2017

Prostate cancer is the second most common cancer in men worldwide. The incidence of prostate cancer is increasing with an ageing population. Since the introduction of prostate-specific antigen testing in Western countries, prostate cancers are now being diagnosed earlier. The treatment of metastatic prostate cancer has progressed dramatically in the past decade and includes advances in chemotherapy, androgen receptor-targeted agents, immunotherapy, radiopharmaceuticals and bone-targeted agents. These new treatments bring a new range of side effects, which must be managed promptly and effectively. An understanding of potential treatment toxicities and their management is essential for nursing staff in order to provide a high standard of care for men with prostate cancer.
Dressings optimisation strategy: Meeting the needs of the patient and the population
Authors: Kilborn Caitlin , Hopkins Alison
Published: April 2017

A managed procurement-based system for the delivery of wound care dressings provides clinical, financial and systemic benefits to the local healthcare economy while meeting the needs of individual patients and supporting informed clinical autonomy. The need for a system and budget that are responsive to local population and service changes, and the potential burden on community nurses to transport dressings can create a challenge. The authors argue that despite these limitations, the benefits are such that questioning current processes by delivering a managed procurement solution is an asset to patients, clinicians and the local health-care economy.
A foot on the ladder
Authors: Lepkowska Dorothy
Published: April 2017

Dorothy Lepkowska explains how a new programme is helping year 6 pupils to develop confidence when it comes to making the move to secondary school.
Mentoring in Sports for the Development of the Successful High School Coach
Authors: Swanson Joel , Deutsch Joe
Published: April 2017

This study involves the surveying of current high school coaches in the state of North Dakota who are certified by the National Federation of High Schools through the completion of the required courses, including “The Fundamentals of Coaching”, “Concussion Diagnosis and Prevention”, as well as CPR, First Aid and AED certification in a current, active status. The participant coaches (n=113), were sent a survey through email using the Qualtrics Survey Program.  This survey contained documentation of demographic information, coaching history, opinions regarding issues in coaching and how they are/can be addressed.  This survey also discussed influences in the coaches life and how they have shaped their coaching careers.  Coaching education and mentoring suggestions are also offered by the subjects as ways to improve the coaching job field as well as struggles they see mentoring bringing if a program were to be introduced.Results indicated that the majority of coaches would be open to mentoring programs in their school.  This includes communication sessions, coaching education, sport specific coaching development, and time for personal interaction with other coaches aimed at creating relationships and discussing professional successes, coaching issues, and questions they have.  Results also show a trend happening.  There is a shortage of coaches with 11-20 years of experience and a large number of head coaches that have less than five years of experience.  This trend is hinting to coaches leaving the profession after ten years, with not a lot of experienced people left to take over.  Young coaches lead to a large learning curve, immaturity with dealing with certain situations, and lack the experience of actually teaching the game itself.
Open Science: Das neue Gold von Wissenschaft sind Forschungsdaten
Authors: Siegfried Doreen
Published: April 2017

Forschungsdaten sind aktuell das zentrale Thema in der bundesdeutschen Wissenschaftspolitik zum Thema digitaler Wandel. Der Rat für Informationsinfrastrukturen (RfII) beispielsweise fordert niedrigschwellige Services für Wissenschaftler, vernetzte Infrastrukturen für Forschungsdaten sowie Forschung zu den sich wandelnden Realitäten im Wissenschaftssystem. Während andernorts noch an weiteren Stellungnahmen und Empfehlungen gearbeitet wird, befasst sich das ZBW-Leibniz-Informationszentrum Wirtschaft bereits jetzt ganz konkret mit der Umsetzung von Forschungsdaten-Projekten.
Convergence of the Rothe Method Applied to Operator DAEs Arising in Elastodynamics
Authors: Altmann Robert
Published: April 2017

The dynamics of elastic media, constrained by Dirichlet boundary conditions, can be modeled as an operator DAE of semi-explicit structure. These models include flexible multibody systems as well as applications with boundary control. In order to use adaptive methods in space, we analyze the properties of the Rothe method concerning stability and convergence for this kind of systems. We consider a regularization of the operator DAE and prove the weak convergence of the implicit Euler scheme. Furthermore, we consider perturbations in the semi-discrete systems which correspond to additional errors such as spatial discretization errors.
The study of structural, elastic, electronic and optical properties of CsYx I(1 − x)(Y = F, Cl, Br) using density functional theory
Authors: Mian Shabeer Ahmad , Muzammil Muhammad , Rahman Gul , Ahmed Ejaz
Published: April 2017

The structural, electronic, elastic and optical properties of CsYx I(1 − x)(Y = F, Cl, Br) are investigated using full potential linearized augmented plane wave (FP-LAPW) method within the generalized gradient approximation (GGA). The ground state properties such as lattice constant (ao) and bulk modulus (K) have been calculated. The mechanical properties including Poisson’s ratio (σ), Young’s modulus (E), anisotropy factor (A) and shear modulus (G) were also calculated. The results of these calculations are comparable with the reported experimental and theoretical values. The ductility of CsYx I(1 − x) was analyzed using Pugh’s rule (B/G ratio) and Cauchy’s pressure (C12−C44). Our results revealed that CsF is the most ductile among the CsYxI(1 − x)(Y = F, Cl, Br) compounds. The incremental addition of lighter halogens (Yx) slightly weakens the strength of ionic bond in CsYxI(1 − x). Moreover, the optical transitions were found to be direct for binary and ternary CsYxI(1 − x). We hope that this study will be helpful in designing binary and ternary Cs halides for optoelectronic applications.
Production, separation and target preparation of 171Tm and 147Pm for neutron cross section measurements
Authors: Heinitz Stephan , Maugeri Emilio A. , Schumann Dorothea , Dressler Rugard , Kivel Niko , Guerrero Carlos , Köster Ullrich , Tessler Moshe , Paul Michael , Halfon Shlomi
Published: April 2017

The knowledge of the neutron capture cross sections of s-process branching point isotopes represents a basic requirement for the understanding of star evolution. Since such branching point isotopes are by definition radioactive, the measurement of their cross sections from thermal to stellar energies becomes a challenging task. Considerable amounts of material have to be produced, representing a significant radioactive hazard. We report here on the production and separation of 3.5 mg 171Tm from 240 mg 170Er2O3 and 72 μg 147Pm from 100 mg 146Nd2O3 irradiated at the ILL high flux reactor. Thin targets were prepared with high chemical and radioisotopic purity suitable for neutron capture measurements at n_TOF CERN and the SARAF-LiLiT facility.
Sebastian Sunday Grève and Jakub Mácha, eds. Wittgenstein and the Creativity of Language
Authors: Fox Craig
Published: April 2017

Basingstoke: Palgrave Macmillan, 2016. 314pp. $99 Hardcover. ISBN 978-1-137-47253-3Reviewed by Craig Fox, California University of Pennsylvania.
Microglial TNFα Induces COX2 and PGI2 Synthase Expression in Spinal Endothelial Cells during Neuropathic Pain
Authors: Kanda Hirosato , Kobayashi Kimiko , Yamanaka Hiroki , Okubo Masamichi , Noguchi Koichi
Published: April 2017

Prostaglandins (PGs) are typical lipid mediators that play a role in homeostasis and disease. They are synthesized from arachidonic acid by cyclooxygenase 1 (COX1) and COX2. Although COX2 has been reported to be upregulated in the spinal cord after nerve injury, its expression and functional roles in neuropathic pain remain unclear. In this study, we investigated the expression of Cox2, PGI2 synthase (Pgis), and prostaglandin I2 receptor (IP receptor) mRNA in the rat spinal cord after spared nerve injury (SNI). Levels of Cox2 and Pgis mRNA increased in endothelial cells from 24 to 48 h after nerve injury. IP receptor mRNA was constitutively expressed in dorsal horn neurons. A COX2 inhibitor and IP receptor antagonists attenuated pain behavior in the early phase of neuropathic pain. Furthermore, we examined the relationship between COX2 and tumor necrosis factor-α (TNFα) in the spinal cord of a rat SNI model. Levels of TNFα mRNA transiently increased in the spinal microglia 24 h after SNI. The TNF receptors Tnfr1 and Tnfr2 mRNA were colocalized with COX2. Intrathecal injection of TNFα induced Cox2 and Pgis mRNA expression in endothelial cells. These results revealed that microglia-derived TNFα induced COX2 and PGIS expression in spinal endothelial cells and that endothelial PGI2 played a critical role in neuropathic pain via neuronal IP receptor. These findings further suggest that the glia–endothelial cell interaction of the neurovascular unit via transient TNFα is involved in the generation of neuropathic pain.
Local and Long-Range Circuit Connections to Hilar Mossy Cells in the Dentate Gyrus
Authors: Sun Yanjun , Grieco Steven F. , Holmes Todd C. , Xu Xiangmin
Published: April 2017

Hilar mossy cells are the prominent glutamatergic cell type in the dentate hilus of the dentate gyrus (DG); they have been proposed to have critical roles in the DG network. To better understand how mossy cells contribute to DG function, we have applied new viral genetic and functional circuit mapping approaches to quantitatively map and compare local and long-range circuit connections of mossy cells and dentate granule cells in the mouse. The great majority of inputs to mossy cells consist of two parallel inputs from within the DG: an excitatory input pathway from dentate granule cells and an inhibitory input pathway from local DG inhibitory neurons. Mossy cells also receive a moderate degree of excitatory and inhibitory CA3 input from proximal CA3 subfields. Long range inputs to mossy cells are numerically sparse, and they are only identified readily from the medial septum and the septofimbrial nucleus. In comparison, dentate granule cells receive most of their inputs from the entorhinal cortex. The granule cells receive significant synaptic inputs from the hilus and the medial septum, and they also receive direct inputs from both distal and proximal CA3 subfields, which has been underdescribed in the existing literature. Our slice-based physiological mapping studies further supported the identified circuit connections of mossy cells and granule cells. Together, our data suggest that hilar mossy cells are major local circuit integrators and they exert modulation of the activity of dentate granule cells as well as the CA3 region through “back-projection” pathways.
Posterior Parietal Cortex Guides Visual Decisions in Rats
Authors: Licata Angela M. , Kaufman Matthew T. , Raposo David , Ryan Michael B. , Sheppard John P. , Churchland Anne K.
Published: April 2017

Neurons in putative decision-making structures can reflect both sensory and decision signals, making their causal role in decisions unclear. Here, we tested whether rat posterior parietal cortex (PPC) is causal for processing visual sensory signals or instead for accumulating evidence for decision alternatives. We disrupted PPC activity optogenetically during decision making and compared effects on decisions guided by auditory versus visual evidence. Deficits were largely restricted to visual decisions. To further test for visual dominance in PPC, we evaluated electrophysiological responses after individual sensory events and observed much larger response modulation after visual stimuli than auditory stimuli. Finally, we measured trial-to-trial spike count variability during stimulus presentation and decision formation. Variability decreased sharply, suggesting that the network is stabilized by inputs, unlike what would be expected if sensory signals were locally accumulated. Our findings suggest that PPC plays a causal role in processing visual signals that are accumulated elsewhere.

SIGNIFICANCE STATEMENTDefining the neural circuits that support decision making bridges a gap between our understanding of simple sensorimotor reflexes and our understanding of truly complex behavior. However, identifying brain areas that play a causal role in decision making has proved challenging. We tested the causal role of a candidate component of decision circuits, the rat posterior parietal cortex (PPC). Our interpretation of the data benefited from our use of animals trained to make decisions guided by either visual or auditory evidence. Our results suggest that PPC plays a causal role specifically in visual decision making and may support sensory aspects of the decision, such as interpreting the visual signals so that evidence for a decision can be accumulated elsewhere.
Sen1 has unique structural features grafted on the architecture of the Upf1‐like helicase family
Authors: Leonaitė Bronislava , Han Zhong , Basquin Jérôme , Bonneau Fabien , Libri Domenico , Porrua Odil , Conti Elena
Published: April 2017

The superfamily 1B (SF1B) helicase Sen1 is an essential protein that plays a key role in the termination of non‐coding transcription in yeast. Here, we identified the ~90 kDa helicase core of Saccharomyces cerevisiae Sen1 as sufficient for transcription termination in vitro and determined the corresponding structure at 1.8 Å resolution. In addition to the catalytic and auxiliary subdomains characteristic of the SF1B family, Sen1 has a distinct and evolutionarily conserved structural feature that “braces” the helicase core. Comparative structural analyses indicate that the “brace” is essential in shaping a favorable conformation for RNA binding and unwinding. We also show that subdomain 1C (the “prong”) is an essential element for 5′‐3′ unwinding and for Sen1‐mediated transcription termination in vitro. Finally, yeast Sen1 mutant proteins mimicking the disease forms of the human orthologue, senataxin, show lower capacity of RNA unwinding and impairment of transcription termination in vitro. The combined biochemical and structural data thus provide a molecular model for the specificity of Sen1 in transcription termination and more generally for the unwinding mechanism of 5′‐3′ helicases.
The MYC mRNA 3′‐UTR couples RNA polymerase II function to glutamine and ribonucleotide levels
Authors: Dejure Francesca R , Royla Nadine , Herold Steffi , Kalb Jacqueline , Walz Susanne , Ade Carsten P , Mastrobuoni Guido , Vanselow Jens T , Schlosser Andreas , Wolf Elmar , Kempa Stefan , Eilers Martin
Published: April 2017

Deregulated expression of MYC enhances glutamine utilization and renders cell survival dependent on glutamine, inducing “glutamine addiction”. Surprisingly, colon cancer cells that express high levels of MYC due to WNT pathway mutations are not glutamine‐addicted but undergo a reversible cell cycle arrest upon glutamine deprivation. We show here that glutamine deprivation suppresses translation of endogenous MYC via the 3′‐UTR of the MYC mRNA, enabling escape from apoptosis. This regulation is mediated by glutamine‐dependent changes in adenosine‐nucleotide levels. Glutamine deprivation causes a global reduction in promoter association of RNA polymerase II (RNAPII) and slows transcriptional elongation. While activation of MYC restores binding of MYC and RNAPII function on most promoters, restoration of elongation is imperfect and activation of MYC in the absence of glutamine causes stalling of RNAPII on multiple genes, correlating with R‐loop formation. Stalling of RNAPII and R‐loop formation can cause DNA damage, arguing that the MYC 3′‐UTR is critical for maintaining genome stability when ribonucleotide levels are low.
Time-lapse imaging of cleavage divisions in embryo quality assessment
Authors: Milewski Robert , Ajduk Anna
Published: April 2017

In vitrofertilization (IVF) is one of the most important procedures for treating infertility. As several embryos are usually produced in a single IVF cycle, it is crucial to select only the most viable ones for transfer to the patient. Morphokinetics, i.e. analysis of the dynamics of cleavage divisions and processes such as compaction and cavitation, has provided both biologists and clinicians with a new set of data regarding embryonic behaviour during preimplantation development and its association with embryo quality. In the current review, we focus on biological significance of morphokinetic parameters and show how they can be used to predict a reproductive outcome. We also explain the statistics behind the predictive algorithms and discuss the future perspectives of morphokinetics.
Anatomical study and variation of the anterior belly of digastric muscle: case report
Authors: Lins Carla Cabral dos Santos Accioly , Correa Diana Isabela Machado , Lima Rafaelle de Souza e , Silva Camila Caroline da , Villarouco Fernanda Maria de Oliveira , Silva Nathalia Alves da , Bezerra Aluizio Jose
Published: April 2017

The digastric muscle is one of the supra hyoid muscles that that assist in the chewing movements, usually consisting of two bellies: one anterior and other posterior, united by an intermediate tendon. This study aimed to report the presence of a previous accessory belly in digastric. The dissection was performed on a human body, adult, male, fixed and preserved in 10% formaldehyde solution, which belongs to the Anatomy Department of the equity of Federal University of Pernambuco, Recife, Brazil. During dissection of the neck in the submental region found a unilateral variation of the left digastric. The accessory belly was inserted into the digastric fossa of the contra lateral jaw, and It was thought attached to previous bellies and later by an intermediate tendon attached to the lower horn of the hyoid bone, and the length 33mm and width of 6mm.Thus, we emphasize the importance of knowledge of the diversity of morphological arrangements as a way to differentiate multiple variations, thus facilitating diagnostic and surgical procedures in the anterior neck.
Validation of New Quality Measures for Transitions Between Sites of Care
Authors: Parast Layla , Burkhart Q. , Desai Arti D. , Simon Tamara D. , Allshouse Carolyn , Britto Maria T. , Leyenaar JoAnna K. , Gidengil Courtney A. , Toomey Sara L. , Elliott Marc N. , Schneider Eric C. , Mangione-Smith Rita
Published: April 2017

BACKGROUND AND OBJECTIVE:

Assessing and improving the quality of transitions to home from the emergency department (ED) or hospital is critical for patient safety. Our objective was to validate 8 newly developed caregiver-reported measures of transition quality.

METHODS:

This prospective observational study included 1086 caregiver survey respondents whose children had an ED visit (n = 523) or hospitalization (n = 563) at Seattle Children’s Hospital in 2014. Caregivers were contacted to complete 2 surveys. The first survey included the newly developed transition quality measures and multiple validation measures including modified versions of Child Hospital Consumer Assessments of Healthcare Providers and Systems (HCAHPS) composites, assessing communication and discharge planning. The second survey (administered 30 days later) included questions about follow-up appointments and ED return visits and readmissions. Using multivariate regression, we examined associations between the newly developed transition quality measures and each validation measure.

RESULTS:

All transition quality measures were significantly associated with ≥1 validation measures. The hospital-to-home transition measure assessing whether discharge instructions were easy to understand, were useful, and contained necessary follow-up information had the largest association with the Child HCAHPS nurse–parent and doctor–parent communication composites (β = 55.6; 95% confidence interval, 43 to 68.3; and β = 48.3; 95% confidence interval, 36.3 to 60.3, respectively, scaled to reflect change associated with a 0 to 100 change in the transition measure score).

CONCLUSIONS:

Newly developed quality measures for pediatric ED- and hospital-to-home transitions were significantly and positively associated with previously validated measures of caregiver experience. These new measures may be useful for assessing and improving on the quality of ED- and hospital-to-home transitions.
PENINGKATAN DAYA TETAS TELUR DAN SINTASAN LARVA IKAN NILA (oreochromis niloticus) MELALUI MANAJEMEN KESEHATAN IKAN
Authors: Supriyadi Hambali , Komarudin Oman , Taufik Pipik , Jangkaru Zulkifli , Asih Sidi
Published: April 2017

Penelitian dilukukan dengan tujuan untuk merrgetuhui bagi peningkatan produksi benih nila melalui penerapan manajemen kesehatan ikan. Penggunaan beberapa nacarn anti jamur untuk perlukuan telur, beberapa antibiotika dan vaksin dengan berbagai dosis untuk peningkatan daya sintasan larva.
PENGARUH PROPORSI ASAM LEMAK HEWANI DAN NABATI PADA PAKAN BUATAN TERHADAP PEMATANGAN GONAD DAN PEMIJAHAN KEPITING BAKAU scylla serrata
Authors: Kasprijo Kasprijo , Yunus M Yunus M , Marzuqi Marzuqi , Sutarmat Tatam , Setyadi Irwan
Published: April 2017

Penelitian ini dilakukan dengan menggunakan hewan uji induk kepiting dengan bobot ratarata 815 g, panjang karapas rata-rata 8,5 cm dan lebar karapas rata-rata 12 cm.
PENGARUH NEOMICYN DAN GRISEOFULVIN TERHADAP INSIDENSI PENYAKIT BAKTERIAL DAN FUNGAL PADA IKAN GURAME (Osphronemmus gouramy Lac.)
Authors: Taufik Pipik , Bastiawan Dayat , Mariyono Mariyono
Published: April 2017

Percobaan untuk penanggulangan penyakit bakterial dan fungal terhadap ikan gurame (Osphronernus gortamy Lac.) dengan menggunakan neomycin dan griseofulvin telah dilakukan di laboratorium penyakit ikan Balai Penelitian Perikanan Air Tawar Sukamahdi pada bulan Juni-Desember 1995.
‘ ¡Quién fuera noche para caerle encima!’ Piropos in Chile: Sexual harassment or ?irtation?
Authors: Abarca Millán Erika
Published: April 2017

Piropos, a type of ?irtatious street talk, are a discourse practice that social movements against street harassment in Chile have condemned for their male chauvinist and sexist content. This paper analyzes the structure of piropos to see their effects in both the way piropos portray women, and the discourse piropos promote and/or maintain towards women. From a compendium (Memoria chilena, 2008), 67 piropos were selected and grouped based on the conceptual metaphor (Lakoff and Johnson, 2003) they use to represent women in society. Conceptual metaphors represented women as religious entities, food, criminals or offenders, and objects found in nature. A ?fth metaphor included under the label ‘trans?guration’ represents the objecti?cation of the one uttering the piropo in order to get closer to the receiver of this discourse practice. The methodology considered (1) power and social distance (Poynton, 1989; Kerbrat-Orecchioni, 1992) to understand the relationship between the participants of this practice, and (2) transitivity (Halliday, 2014) to understand how lexical choices of both processes and participants re?ect how human experience is expressed. The analysis revealed that the piropos analyzed use several resources to perpetuate a male chauvinist discourse that objecti?es women and considers them as inferior and, generally, powerless.
Discourse in f(r)iction. Production and reception of gender roles discourse in an audio-visual text about piropos
Authors: Canale Germán
Published: April 2017

This paper studies the constraints the audience – and also producers – ?nd when attempting to deconstruct a traditional gendered practice (piropos) in a recent ?ctional clip that depicts this practice in an unconventional way, with women as the performers. The production of the clip is analyzed using multimodal discourse analysis tools to explore how the audiovisual text (re)produces speci?c gender(ed) meanings at the interplay of several semiotic resources. The reception of the clip is analyzed with the aid of the appraisal model, to study how participants in three focus groups (female, male and mixed) interactively co-construct meanings to evaluate the clip, the producers, the narrative and even the piropos depicted. The discussion centers on three aspects evaluated by participants: the genre/purpose of the text, its open ending or the lack of an explicit moral, and the mismatch between ?ction and social reality.
‘¡Uy!, ¿quién pidió pollo?’ A qualitative analysis of the piropo practice by construction workers in Bogotá, Colombia
Authors: Ramírez-Cruz Héctor , Correa Nataly , Mancera Jennifer
Published: April 2017

This paper analyzes the discursive practice of piropos performed by construction workers and addressed to female pedestrians in Bogotá, Colombia. Following an interactional sociolinguistic approach, the paper investigates the distinctive features of the piropo practice within this group. The investigators collected 87 naturalistic interactions and 40 interviews of speakers using ethnographic techniques. The analysis includes the study of the content and the form of piropos along with body language and the general performance of the speaker and the addressee. The results show that the speakers follow the patterns of piropo interactions in the Hispanic culture, even though they use specific features for the preparatory acts, the enunciation, and the offset of piropos. The observational data suggest that the practice is grounded on machismo ideologies that trigger public deployment of masculinity. On the other hand, interview data display speakers’ perceptions of piropos as a flirtatious activity and a verbal game. The paper provides naturalistic evidence of the piropo practice in a Hispanic context and contributes to the discussion of gender roles in the public space.
Street remarks to women in five countries and four languages: Impositions of engagement and intimacy
Authors: Bailey Benjamin
Published: April 2017

In this paper I analyze the remarks men make to passing young women on the street in 134 naturally occurring encounters that were video recorded in 2013 and 2014 across ?ve countries and four languages and posted on the internet. I categorize these remarks in terms of the speech acts they contain, showing the most common acts, in descending order of frequency, to be addressing, greeting, expressing astonishment or admiration, summoning, and asking rhetorical questions. In immediate interactional terms, the great majority of the men’s actions are thus oriented to constituting what Goffman (1963) called a ‘focused interaction’, a face-to-face engagement with a common focus of attention. The very ordinariness of these acts in terms of content and surface meaning – they are not vulgar or explicitly threatening – may explain why defenders of street remarks regularly draw attention to seemingly benign referential or speech act content, e.g., ‘He was just saying “Hi”’ or ‘He was just giving her a compliment’. At another level, however, street remarks impose intimacy on passing strangers, thus ?outing the normative conventions for interaction through which we manage social and personal risk and establish trust. Women targeted by street remarks treat them as breaches by not responding to them. The very ordinariness of the language in the street remarks documented, along with the relative dif?culty of articulating the implicit social conventions that they breach, may veil their harm and indirectly contribute to the perpetuation of male domination of women in public spaces.
Language, gender and sexual identity: Poststructuralist perspectives Heiko Motschenbacher (2010) and An interdisciplinary bibliography on language, gender and sexuality (2000–2011) Heiko Motschenbacher (2012)
Authors: Acuña Ferreira A. Virginia
Published: April 2017

Language, gender and sexual identity: Poststructuralist perspectives Heiko Motschenbacher (2010) Amsterdam and Philadelphia: John Benjamins. Pp. xii + 209 ISBN: 978 90 272 1868 1 (Hb; alk. Paper) ISBN 978 90 272 8750 2 (Eb)

An interdisciplinary bibliography on language, gender and sexuality (2000–2011) Heiko Motschenbacher (2012)Amsterdam and Philadelphia: John Benjamins. Pp. vii + 294 ISBN: 978 90 272 1200 9 (Hb; alk. Paper) ISBN 978 90 272 7315 4 (Eb)
Gestão Participativa e a interface com trabalhadores do Sistema Único de Saúde: uma revisão integrativa
Authors: Gabriel Lopes Thais Rosental , Carvalho J. B. L. , Ramos N. O. F. , Câmara A. G. , Teixeira G. A.
Published: April 2017

Trata-se de uma revisão integrativa de literatura com objetivo de integrar o conhecimento produzido acerca da Gestão Participativa e a interface dos trabalhadores do SUS. Para seleção dos artigos foram consultadas três bases de dados – Scielo, LiLACS e MEDLINE  - sendo incluídos doze artigos. Os resultados mostram estudos qualitativos, todos publicados entre 2008 a 2012. Identificou-se nos artigos que a Gestão Participativa é vivenciada por trabalhadores de saúde, muito embora haja dificuldades para a mesma. Os resultados evidenciaram um maior número de estudos nas regiões sul e sudeste brasileiro. Conclui-se que a Gestão Participativa é importante para o desenvolvimento do SUS e que é possível superar desafios e fazer com que o trabalhador de saúde participe mais do processo de decisões.
VIOLÊNCIA SIMBÓLICA NA EPT – UM ESTUDO DE CASO NO CURSO TÉCNICO DE ENFERMAGEM DO INSTITUTO HUMBOLDT DE VITÓRIA/ES.
Authors: Bravo Rafaela Gomes
Published: April 2017

Trata-se de um estudo de caso, que contou com a participação de três turmas do curso técnico de enfermagem, do Instituto Humboldt, da cidade de Vitória/ES.  O trabalho se baseia no entendimento de Pierre Bourdieu, sociólogo francês, que por meio de sua teoria do habitus, afirma que a dominação sócio-econômica é majoritária e primeiramente reproduzida, pela dominação cultural. Em seus estudos voltados para a área educacional, constatou que é através da violência simbólica reproduzida no ambiente escolar, que a cultura dominante se naturaliza e se impõe como universal e superior. A partir deste entendimento, o presente trabalho teve como objetivo levantar os casos da violência simbólica no contexto pedagógico do curso técnico em enfermagem, verificar os problemas ocasionados por tal violência e identificar se os professores têm implementado ações que visem diminuir esses problemas. A pesquisa caracteriza-se como exploratória, qualitativa, se embasou em um estudo de caso, por meio de entrevistas semi-estruturadas. Após a análise fenomenológica dos dados, foi possível confirmar a hipótese levantada.
A FORMAÇÃO DOS TRABALHADORES TÉCNICOS DE SAÚDE COMO OBJETO DE ESTUDO NOS PROGRAMAS DE PÓS-GRADUAÇÃO STRICTU SENSU, NO BRASIL (2002-2016)
Authors: Costa Thais Paulo , Silva Lenina Lopes Soares
Published: April 2017

A história da Educação Profissional em Saúde, no Brasil, tem como grande marco a década de 1980, inserida nas lutas sociais com a finalidade de conquistar um maior reconhecimento para os trabalhadores de nível técnico, considerando que estes atuavam nos serviços de saúde com precária qualificação e sem reconhecimento profissional. A criação das Escolas Técnicas de Saúde pode ser considerada como uma das principais conquistas, destacando-se o seu papel social e político. Entretanto, as formações desses trabalhadores ainda encontram-se em um cenário associado à forte flexibilização e precarização das relações de trabalho que tendem a afetar as formações da subjetividade e o reconhecimento social desses profissionais. Este artigo apresenta como objetivo fazer um levantamento da produção do conhecimento sobre a Formação Técnica em Saúde nos Programas de Pós-Graduação Strictu Sensu, no Brasil, no período de 2002 a 2016, tendo como objetivo específico apresentar os procedimentos metodológicos adotados pelos autores nessas produções. A pesquisa foi desenvolvida no mês de agosto de 2016 no repositório do Portal da Coordenação e Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Os resultados apresentaram nove dissertações de mestrado: três de caráter exploratório, quatro estudos de caso, uma pesquisa documental, uma pesquisa avaliativa e uma tese que utilizou a análise documental como procedimento metodológico.
A CONCEPÇÃO DE FORMAÇÃO HUMANA NOS CURSOS DE LICENCIATURAS DO INSTITUTO FEDERAL DE EDUCAÇÃO CIÊNCIA E TECNOLOGIA DA PARAÍBA – IFPB
Authors: Lucena Francineide Fernandes
Published: April 2017

O artigo visa analisar o conceito de formação humana presente nos projetos pedagógicos dos cursos de licenciatura em química e matemática ofertados pelo Instituto Federal de Educação, Ciência e Tecnologia da Paraíba- IFPB.  Adotaremos o conceito de formação humana presente no pensamento gramsciano, o qual defende a indissociabilidade entre conhecimento histórico, práxis política e formação humana. Trata-se de estudo bibliográfico, onde foram consultados livros, artigos científicos, leis e os projetos pedagógicos dos referido cursos. Contata-se que os conceitos de formação docente e formação humana presentes nos  projetos pedagógicos  dos referidos cursos apresentam pontos de convergência com o pensamento gramsciano, ao buscarem uma formação omnilateral, privilegiando a interdisciplinaridade e a contextualização dos conhecimentos.
Kidney transplantation and bone disease: risk factors of development and diagnostics
Authors: Vetchinnikova O. N.
Published: April 2017

Bone disease is a serious and common condition in patients after kidney transplantation. The review analyzed the causes of bone disorders in the early and late postoperative period that are associated with renal transplantation: fibroblast growth factor 23, parathyroid hormone, vitamin D, immunosuppressive therapy and imbalance of mineral metabolism. It shows the most common clinical variant of the post-transplant bone disease – secondary osteoporosis, risk factors of its development and complications. It presents the diagnostic algorithm for dynamic monitoring and evaluating the effectiveness of the treatment of bone disorders
Cystatin C in the diagnostics of acute kidney injury after heart transplantation
Authors: Strokov A. G. , Poz Ya. L. , Poptsov V. N. , Shevchenko A. O. , Shmerko N. P.
Published: April 2017

Aim. To examine the assumption that significant concentrations of cystatin C in urine are the manifestation of the tubular necrosis and, respectively, the severity of kidney damage after heart transplantation (HTx).

Materials and methods. In this study we evaluated 33 heart recipients (6 women and 27 men, aged from 24 to 68 years old) who had risk factors of acute kidney injury: serum creatinine level >113 μmol/l and/or mechanical circulatory support requirement (20 patients, in 14 cases before HTx). Cystatin C concentration in serum and in urine was measured by DyaSis particle-enhanced immunoturbidimetric assay test «Cystatin C FS».

Results. Recipients were divided into two groups according to the levels of cystatinuria. In the group with the significant (more than 0.18 mg/l) urinary cystatin C concentrations the requirement of renal replacement therapy (RRT) was 2.5-fold higher, and the mean duration of RRT was more than 10-fold longer. In 2 patients with the significant cystatinuria acute kidney injury (AKI) has transformed into end-stage renal disease (ESRD).

Conclusion. Due to data obtained we may suppose that significant concentrations of cystatin C in urine are the marker of the tubular necrosis with the prolonged RRT requirement. Further studies are needed to justify this relationship.
Perioperative period in cardiac transplantation from donors with brain death due to methanol poisoning
Authors: Poptsov V. N. , Spirina E. A. , Pchelnikov V. V. , Ukhrenkov S. G. , Masyutin S. A. , Voronkov V. Yu. , Aliev E. A. , Ustin S. Yu.
Published: April 2017

The successful use of donor hearts from people died of methanol poisoning helps reducing the deficit of donor organs for patients requiring urgent cardiac transplantation [3]. We present our experience of successful cardiac transplantations from 2 donors who died due to methanol poisoning. Given the possibility of performing a cardiac transplant from this group of donors a protocol has been developed at the V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation which includes clinical, laboratory and instrumental criteria for the selection of heart donor and recipient. The possibility of delayed onset myocardial contractile dysfunction due to methanol poisoning means that a longer conditioningperiod is vital as well as compulsory clinical, laboratory and expert chocardiographic examinations of the potential donor heart.
Kidney injury and renal replacement therapy in heart transplant recipient
Authors: Poz Ya. L. , Strokov A. G. , Poptsov V. N. , Kopylova Yu. V. , Kryshin K. N.
Published: April 2017

The development of kidney injury and the characteristics of renal replacement therapy were considered in patient with dilated cardiomyopathy, who consequently underwent two heart transplantations and two kidney transplantations. Since the number of the patients needed both kidney and heart transplantation increases constantly, the multifaceted thorough research in this specific patient population is extremely important.
Cellular neuroprotection as a modern treatment approach for optic neuropathy
Authors: Borzenok S. A. , Khubetsova M. Kh. , Saburina I. N. , Gavrilova N. A. , Tonaeva Kh. D. , Ostrovskiy D. S. , Lanevskaya N. I. , Kosheleva N. V. , Zurina I. M.
Published: April 2017

Aim.To develop technology to create 3D-spheroid multipotent mesenchymal stem cells (MMSC) of limbal cadaveric human eyes, capable of safe and long-term secretion of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF).

Materials and methods.MMSC were obtained by cultivation of limbal fragments, released from cadaveric donor human eye. Cultivation was carried out in DMEM/F12 medium, supplemented with L-glutamine, penicillin, streptomycin, amphotericin B, HEPES, insulin, dexamethasone and 10 vol.% FBS under standard conditions (5% СО2, 37 °C), medium change was performed every 3 days. To determine the phenotype of the received cell culture the method of immunophenotyping by marker proteins to MMSC (CD73, CD105, CD19, CD90, CD133) was used. Stimulation of neurotrophic factor secretion was performed via a twostep procedure. 3D-cell spheroids were created with the help of agarous plates for three groups of comparison, where group I was control group, spheroids of intact 2D-culture MMSK; group II – spheroids of previously induced 2D-culture MMSC; group III – spheroids of 2D-MMSC induced on the 1st day of cultivation. Cell cultures supernatants were selected in different periods for NGF and BDNF follow-up study by ELISA procedure.

Results. Induction of 3D-spheroids of limbal MMSC promotes short-term increase of the level of BDNF and NGF, but further, the secretion of these factors significantly decreases. Induction leads to a change in the morphology of spheroids: loss of compactness and emergence of «fringed» (debris). Such changes indicate of frailty of received constructions. Spheroids from previously induced MMSC are capable of stable NTF secretion, but the level of secretion is much less as compared to the control group.

Conclusion.3D-cell culture of intact 2Dculture of limbal MMSC can be considered as cellular medication for a safe and long-term neuroprotection in optic neuropathy treatment.
Assessment Methods of Quality of Life of Living Organ Donors
Authors: Gautier S. V. , Konstantinov V. K.
Published: April 2017

The study of quality of life of living organ donors in transplantation by questionnaires has increasingly become the subject of clinical studies. However, there are no unified criteria and standard norms of quality of life. Each questionnaire has its own criteria and evaluation scale. This review presents the main general questionnaires that have been applied worldwide for the quality of life assessment of living kidney and liver donors. Special questionnaires used to refine the parameters of quality of life and their coordination with common questionnaires are considered. Optimal questionnaire to detect quality of life in modern research for living organ donors is identified.