bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategic Planning in Decision Making Against the Information Perspective
Authors: Hadijaya Yusuf , Abdillah Fazli , Sembiring Fima Muhazri , Muliyani Sri
Published: December 2022

The development of science and information technology has changed the perspective and lifestyle of the Indonesian people in carrying out their activities. The existence and role of information technology has brought a new era of development in all fields, but these developments have not been matched by an increase in human resources that determine the success of the institution's goals. Information is any form of communication that adds understanding and knowledge, which is useful for the recipient of the information. Information is like blood that flows in the body of an organization. The source of information is data, namely facts that describe real events and real entities. Data is a raw form that cannot tell much, so it needs to be processed further. Data is processed through a model to produce information. Strategic planning is a process carried out by an organization to determine strategy or direction, and make decisions to allocate its resources to achieve the strategy. The term strategic planning was originally known among the military, in this case it implies planning operations to the opponent's area by taking into account all the possibilities, advantages and disadvantages and taking into account the real conditions they have and the existing environmental conditions by trying to take into account the opponent's strengths so that the military operation is carried out. worked out well.
The Improving Beginning Reading Skills Using Structural Analytic Synthetic (SAS) Methods in Elementary Schools
Authors: Rahmi Suci Ika , Kusuma Yanti Yandri , Aprinawati Iis
Published: December 2022

This study aims to determine the improvement of students' initial reading skills on the theme of me through the Synthetic Structural Analytical Method (SAS) in grade 1 of the State Elementary School 001 Pulau. This research is a classroom action research. The subjects of this research are teachers and students. Meanwhile, the object of this research is the Structural Analytical Synthetic (SAS) method and the students' initial reading skills. This research was carried out in 2 cycles, each cycle was carried out in 2 meetings. Data collection techniques used in this study were observation, tests and documentation. Based on the results of the study that before the action 2 students or 10% were in the complete category and 17 students or 89% were in the incomplete category. Then corrective action was taken using the Structural Analytic Synthetic (SAS) method. In the first cycle of students' initial reading skills there was an increase, 4 students or 22% were in the complete category and 14 students or 77% were in the incomplete category. In cycle II, the students' initial reading skills increased again to 16 students or 88% were in the complete category and only 2 students or 11% were in the incomplete category. Thus, it can be concluded that the Structural Analytical Synthetic (SAS) method can improve students' initial reading skills on the theme of me in grade 1 of the State Elementary School 001 Pulau.

Keywords: Beginn
Modification of Wooden Ball Bullets to Improve the Skillful Motion of Bullet Repellent Games Against Elementary School Students
Authors: Nia Thesya Alda , Munir Ali , Suhartini Bernadeta
Published: December 2022

The modification of wooden ball bullets is a model invention with a combination of woodball sports games with bullet repulsion, this is in line with the conditions both in terms of anthropometry and physical conditions in elementary school students which is certainly less effective when using iron balls, because the learning system in elementary school students is only limited to introducing the game. The purpose of this study is that the modification of the wooden ball bullet model can be implemented for students, especially elementary schools, so that students will feel more happy and happy because the learning is very creative and relatively not monotonous and can minimize the allocation of time and the lack of existing infrastructure. In this study, the researchers used the Class Action Research method with class V student sample data consisting of 22 students. The instruments in this study used observation data collection techniques and bullet repellent skilled motion tests. From the study, it was found that there was an increase in pre-cycle to cycle I with learning completion of (54.53%) and continued in cycle II with learning completion results of (86.38%). Of course, it can be concluded that using a modified model of wooden ball bullets is very useful for the community, especially educators, in an effort to improve the movement of game skills in athletics in the bullet repulsion number.
Lack of Parental Attention to Early Childhood Behavior in the Village of Timbang Lawan
Authors: Harahap Ade Chita Putri , Dewi Apriana , Sipahutar Siti Komariah , Nafisha Jihanda , Daulay Maruba Alianna
Published: December 2022

Parental parenting is very important for child development, especially early childhood. Early childhood is a very sensitive time, because parents must be able to provide positive things to help children’s psychological and mental growth as well as the community in Timbang Lawan Bahorok Village. In the implementation of the study we used the interview method as an instrumental tool. During a visit to the village of Timbang Lawan Bahorok we found that many parents ignored the impotance of parenting and support involving children. We also see a lack of parental readness in educating. They think that the role of parents is an easy thing, which is only limited to feeding, sending and caring, but basically parents are the main key to the child’s psychic and emotional development. As parent’s, they should pay more attention, understand and get closer to the child. If the parenting style given by the parents is good, the child will bring out a good attitude and have good character.
Technological Knowledge (TK) of Elementary School Teacher Education Program Students in Elementary Science Learning
Authors: Trivena Trivena , Hakpantria Hakpantria , Lolotandung Reni
Published: December 2022

Teaching is a component of the success of education. Technological knowledge (TK) or technological knowledge, which is one of the frameworks of technological pedagogical content knowledge (TPACK), is knowledge that students possess in order to be able to transmit or impart content to facilitate understanding for students. The aim of this study was to identify the kindergarten students of prospective primary school teachers in elementary science learning. This study uses a descriptive type of research with a quantitative approach. The research population are the students of the UKI Toraja Elementary School Teacher Education Class of 2019. While the research sample consists of students who have taken the courses Introduction to School Fields, Science Learning Development, and Computer Applications, there are no less than 72 respondents. The instrument used is an instrument developed from the research of Akyuz, Desstya, and Mishra, tested for validity and reliability and specially designed for the elementary school level. Data processing is done using the Microsoft Excel application, where the collected data is then searched for the average score per indicator and category. The results of the study showed that the average overall TK of the primary school teacher candidates in elementary science instruction was 7,3. From these results, it can be concluded that the kindergarten teacher candidates for primary school are classified as "high" in science lessons.
The Influence of Online Games on Junior High School Students in North Sumatera Province
Authors: Amanda Gilang Surya , Risma Ade , Amalia Muhayni , Siregar Muhammad Fathlinnas , Daulay Annisa Arrumaisyah
Published: December 2022

This study discusses the effect of online games on junior high school students in Tanjung Morawa sub-district, Deli Serdang district. The influence of online games can cause physical, mental and mental damage to junior high school students in general. In addition, changes in the behavior of students who are addicted to online games are not felt, but can be felt by people in the environment, especially parents. Children's social personality can be felt by people in the environment, especially parents. This study used qualitative research, the object of research was students aged 14-16 years in junior high school in Bandar Labuhan Village, Tanjung Morawa District, Deli Serdang Regency. This data is interviewed and the reality at school. The analysis includes research results and conclusions. This research proves that online game addiction can affect the personality of junior high school students, namely aggressive traits and attitudes, competition between friends, disputes/quarrels between friends, cooperative attitude, egotistical, he will focus on the game and not think about the environment around him.
Do Intestinal Microbiota and Thyroid Travel in Tandem?
Authors:   Section of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy, E-mail: giuseppe. merra@uniroma2.it (GM)., Merra Giuseppe , Capacci Annunziata ,   Department of Medical and Surgical Sciences, Agostino Gemelli General Hospital Foundation-IRCCS, Rome, Italy, E-mail: nunziacapacci@gmail.com., De Lorenzo Antonino ,   Section of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy, E-mail: giuseppe. merra@uniroma2.it (GM)., Di Renzo Laura ,   Section of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy, E-mail: giuseppe. merra@uniroma2.it (GM)., Gualtieri Paola ,   Section of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy, E-mail: giuseppe. merra@uniroma2.it (GM)., Dri Maria ,   Section of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy, E-mail: giuseppe. merra@uniroma2.it (GM)., Frank Giulia ,   School of Specialization in Food Science, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy., Marchetti Marco ,   School of Specialization in Food Science, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Published: December 2022

The gut microbiota exerts some pivotal metabolic functions in digestion and absorption of nutrients [1], detoxification and synthesis of vitamins [2]. Furthermore, it is essential in correct development of lymphoid tissue associated with intestine (GALT) [3], the largest component of the lymphoid system, which contains over 70% of the total immune system.
Pendant Drop Tensiometer: A Valuable Tool for the Characterization of the Foaming Properties and the Interfacial Behavior of Protein Solutions.
Authors:   Montpellier University, UMR IATE, Place E. Bataillon, 34095 Montpellier Cedex 5, France., LAJNAF Roua , ATTIA Hamadi ,   Alimentary Analysis Unit, National Engineering School of Sfax, BPW 3038, Sfax, Tunisia., Ali AYADI Mohamed ,   Alimentary Analysis Unit, National Engineering School of Sfax, BPW 3038, Sfax, Tunisia.
Published: December 2022

Pendant drop tensiometry was usually used to determine the surface elasticity and different kinetic parameters from a modified dynamic surface tension measurement in order to characterize milk protein adsorption behavior to the air/water interface.
Biotechnological applications of Clostridium thermocellum and Bacillus coagulans
Authors:   Department of Biotechnology, Faculty of Life Sciences & Informatics, Balochistan University of Information Technology, Engineering and Management Sciences (BUITEMS), Takatu Campus, Airport Road, Quetta, Balochistan, Pakistan., Tabassum Khan Nida
Published: December 2022

Clostridium thermocellum and Bacillus coagulans both bacteria hold commercial biotechnological importance because of their capability to produce numerous industrial products such as Clostridium thermocellum due to its cellulose fermenting capability are used either as pure or as co–cultures to produce alternative sustainable energy sources such as biofuels including bioethanol, biogas, organic acid, acetic acid derivatives.
Depressed Women and Household Food Security Status
Authors:   National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Mirzadehahari Zahra , Khorramrouz Fatemeh ,   Department of Nutrition, School of Medicine, Mashhad University of medical Sciences, Mashhad, Iran., Gohari Morteza ,   Department of Nutrition, School of Medicine, Mashhad University of medical Sciences, Mashhad, Iran., Amin Senobari Mohammad ,   Department of Nutrition, School of Medicine, Mashhad University of medical Sciences, Mashhad, Iran., Sotoudeh Gity ,   Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran., Khosravi Maryam ,   Department of Nutrition, School of Medicine, Mashhad University of medical Sciences, Mashhad, Iran. International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Published: December 2022

Introduction: Household food insecurity (HFI) has become a major public health concern throughout the world. In addition, depression, as one of the main causes of disability, affects 350 million people worldwide. Given that both problems have a high prevalence, we investigated the relationship between depression and household food insecurity in this study.
Volume and Perfusion Index Evaluation by 3D SPECT Image Processing in Lung Embolism
Authors:   Assoc. Prof. in the Department of Radiology, Medical Physics Unit, National and Kapodistrian University of Athens, Athens, Greece. Phone: +302109840954, Lyra Georgosopoulou Maria ,   email mlyra@med.uoa.gr., Gavrilelli Maria ,   Med Phys. Medical Imaging Centre “Iatriki Apeikonisi” Athens, Greece., Lyra Vasiliki ,   Dept. of Nuclear Medicine, General University Hospital of Larissa, Larissa, Thessaly, Greece., Kokona Georgiana ,   Med Phys. in Cyprus Ministry of Health, Medical &Public Health Services, General Hospital of Nicosia, Nicosia, Cyprus., Skouroliakou Katerina ,   Prof. Department of Physics, University of West Attica (UNIWA).
Published: December 2022

Lung status during pulmonary embolism and patient follow-up, should be evaluated and the accurate estimation of lungs volume is important; By 3-dimensional (3D) medical imaging data and diagnosis of patient embolism become much more reliable.
Crosstalk between Autism Spectrum Disorder and Epilepsy: An insight into the Experimental Models
Authors:   PhD student, Department of Pharmacology, Post Graduate Institute of Medical Education & Research (PGIMER), 4th Floor, Research Block B, Chandigarh, India- 160012., Sandhu Arushi , Rawat Kajal ,   PhD student, Department of Pharmacology, Post Graduate Institute of Medical Education & Research (PGIMER), 4th Floor, Research Block B, Chandigarh, India- 160012., Gautam Vipasha ,   PhD student, Department of Pharmacology, Post Graduate Institute of Medical Education & Research (PGIMER), 4th Floor, Research Block B, Chandigarh, India- 160012., Saha Lekha ,   Professor, Department of Pharmacology, Post Graduate Institute of Medical Education & Research (PGIMER), 4th Floor, Research Block B, Chandigarh, India- 160012.
Published: December 2022

The co-existence of autism spectrum disorder (ASD) and epilepsy is very much prevalent in certain neurodevelopment disorders and their association could be best understood by examining shared phenotypes, pathophysiological mechanisms and risk factors involved.
Van Der Woude Syndrome with Ectodermal Dysplasia- Case Report
Authors: MG Devi , GVMG Manoharan , KB Lakshmi
Published: December 2022

Congenital lip pits of the lower lip are rare developmental malformation with high penetrance, variable expressivity, and autosomal dominance. The cardinal signs in Van der Woude syndrome are congenital lower lip pits, cleft lip with or without cleft palate, and isolated cleft palate. Hypodontia is a cardinal feature that is associated with this syndrome. Ectodermal Dysplasia (ED) is a rare group of inherited disorders manifested with a defect in hair, skin, teeth, and eccrine glands. In ED there are defects in the development of tissues derived from primary embryonic ectodermal derivatives. Dry skin and sparse hair are common features seen in these patients. Partial or complete absence of teeth is reported in ectodermal dysplasia. This is a case report of an 18-year-old male with combined features of Van der Woude Syndrome (VWS) and Hypohidrotic Ectodermal Dysplasia (HED). The patient was surgically managed for the cleft lip at an early age.
Teka-Teki Silang dan Video Animasi Meningkatkan Pengetahuan Gizi Seimbang pada Anak Usia Sekolah
Authors: Putri Andita Arifianita , Wahyuningsih Utami , Sofianita Nur Intania , Fatmawati Iin
Published: December 2022

Nutritional problems in school-age children can occur because of less knowledge. School-age period is the right time for provide nutrition education. Nutrition education needs the interesting and fun media to make it easier to understand, such as crossword puzzles and animation videos. This study aims is to determine the influence of nutrition education with crossword puzzles and animation videos on balanced nutrition knowledge in school-age children. The methods that used is a quasi-experimental with a pretest and posttest group design. The 54 students aged 10 to 12 from fifth graders were selected by stratified random sampling and divided into two media groups. The statistical tests utilized are the independent and paired sample t-tests. The majority of responders were male (63%) and 11 years old (79.6%). The results showed that there were differences in the influence of nutrition education before and after being given crossword puzzles (p = 0.003) and animation video (p = 0.000) on balanced nutrition knowledge. The results also showed that there was no difference in the effectiveness of nutrition education between crossword puzzles and animated videos on balanced nutrition knowledge (p = 0.987). Crossword puzzles and animation videos have an impact for given balanced nutrition education on school-aged children. Animation videos is more effective in increasing balanced nutrition knowledge on school-age children compared to crossword puzzles. It is recommended that the government and schools implement nutrition education initiatives using engaging and entertaining media, such as animation videos.
Okul Müdürlerinin Hizmetkâr Liderlik Davranışları ile Çatışma Yönetme Stilleri Arasındaki İlişki
Authors: Bilgivar Orkun Osman , Topal Mustafa Reşit
Published: December 2022

Bu araştırmada okul müdürlerinin hizmetkâr liderlik davranışları ile çatışma yönetme stilleri arasındaki ilişki öğretmen görüşlerine göre incelenmiştir. Çalışmada nicel araştırma yöntemlerinden “ilişkisel tarama modeli” kullanılmıştır. Araştırmanın evreni, 2021-2022 öğretim yılında İstanbul ilinde resmî ve özel okullarda çalışan; kolayda örneklem ile ulaşılan 1628 öğretmenden oluşmaktadır. Verilerin toplanmasında “Kişisel Bilgi Formu”, Kılıç & Aydın (2016) tarafından Türkçeye uyarlanan “Hizmetkâr Liderlik Ölçeği” ve Rahim (1983) tarafından geliştirilmiş olan ve Gümüşeli (1994) tarafından Türkçeye uyarlanan “Çatışma Yönetim Stilleri Ölçeği” kullanılmıştır. Bulgular için “t-testi, ANOVA, korelâsyon ve regresyon analizi” uygulanmıştır. Araştırma neticesinde, okul müdürlerinin hizmetkâr liderlik davranışları “çok yüksek” düzeyde bulunmuştur. Okul müdürlerinin çatışma yönetiminde ise en fazla “Tümleştirme” stilini ve sırasıyla “Uzlaşma, Ödün Verme, Kaçınma Ve Hükmetme” stillerini tercih ettikleri sonucuna ulaşılmıştır. Okul müdürlerinin hizmetkâr liderlik davranışları ile “tümleştirme” stili arasında pozitif yönlü yüksek düzeyde ilişki, “uzlaşma ve ödün verme” stilleriyle pozitif yönlü orta düzeyde ilişki ve “kaçınma” stiliyle pozitif yönlü düşük düzeyde ilişki olduğu sonucuna ulaşılmıştır. “Hükmetme” stiliyle negatif yönlü düşük düzeyde ilişki olduğu bulunmuştur. Okul müdürlerinin hizmetkâr liderlik davranışlarının çatışma yönetiminde “tümleştirme, uzlaşma, ödün verme ve kaçınma” stillerini pozitif yönde anlamlı yordadığı sonucuna ulaşılmıştır. “Hükmetme” stilini ise negatif yönde anlamlı yordadığı bulunmuştur.
Rehberlik Araştırma Merkezlerinde Eğitsel Değerlendirme Yapan Personelin Çoklu Yetersizliği Olan Bireyleri Değerlendirme Süreçlerine İlişkin Görüşleri
Authors: ÇAY Evgin , SİVRİKAYA Tuğba , ELDENİZ ÇETİN Müzeyyen
Published: December 2022

Bu araştırmada, Rehberlik ve Araştırma Merkezlerinde (RAM) eğitsel değerlendirme yapan personelin çoklu yetersizliğe (ÇY) sahip bireyleri değerlendirme sürecine ilişkin görüşlerinin belirlenmesi amaçlanmıştır. Araştırmaya, dördü kadın, beşi erkek olmak üzere toplam dokuz rehberlik araştırma merkezi çalışanı katılmıştır. Araştırma nitel araştırma desenine göre kurgulanmış olup araştırmada yarı yapılandırılmış görüşme tekniği ile veriler toplanmıştır. Görüşmeler 7-17 dk arasında sürmüştür. Yapılan görüşmelerden elde edilen veriler betimsel analiz tekniği ile çözümlenmiştir. Araştırma sonucunda ÇY sahip bireylerin rehberlik araştırma merkezlerine bireysel olarak ve okulların yönlendirmesiyle başvurduklarını, RAM’ın fiziki yapısından kaynaklı güçlükler yaşadıklarını, eğitsel değerlendirme yaparken mevcut ölçme araçlarını kullandıklarını ifade etmişlerdir. RAM’da çalışan personel, ÇY olan çocukları eğitim ortamına yerleştirmede veliyi ikna konusunda problem yaşadıklarını, yerleştirme yaparken; yerleştirilecek okulun uzaklığı, öğrenci servisi, sınıfların fiziki yapılarının ve imkânlarının göz önüne alındığına yönelik görüş bildirmişlerdir. Çocuğun engel durumuna ve veli isteğine göre, çocuğun ilerleme durumuna göre destek eğitim sağlandığını, değerlendirirken ailelerin onayının alındığını ve aile katılımı için ailelerin bilgilendirildiğini bildirmişlerdir. Eğitsel değerlendirme ve yerleştirme sürecinde özel eğitim öğretmenleri, rehber öğretmen, aile, okul idarecileri ve psikolojik danışmanın yer aldığını ifade etmişlerdir. Eğitsel değerlendirme ve yerleştirme süreçlerinin iyileştirilmesi için önerilere yer verilmiştir.
Investigation of Teacher's Role and Task on the Basis of Social Emotional Learning in After-School Coding Courses
Authors: GÖRHAN Meryem Fulya , ALTUN Arif
Published: December 2022

After-school courses include programs in which students participate voluntarily according to their wishes and interests. In after-school coding course, which is one of these programs, block-based coding tools are studied and practiced in small groups in general. These courses have many positive effects, such as increasing the students' school performance and supporting their positive attitudes. In addition, social emotional learning, which covers the features desired by today's business world, can be supported by these courses. In literature, there are studies on the role and tasks of the teacher in formal education; however, there are no studies on determining the roles and tasks of the teacher in after-school courses. This study aims to examine the role and tasks of the teacher in the coding courses after school based on social emotional learning. For this purpose, one-on-one and focus group interviews were conducted with seven teachers who gave after-school coding courses. Content and frame analysis were performed on the obtained data, and three themes emerged: peer relations, self-regulation, and task consciousness. As a result of the study, it was seen that teachers fulfill the roles of observer, communicator, manager, counselor, organizer, and supporter.
Bilginin Düzenlenmesinde Kataloglama Etiği: İlkeler ve Sorunlar
Authors: BEYGİRCİ Burak
Published: December 2022

Kataloglama, genellikle bu konuda eğitim almış kütüphaneciler tarafından koleksiyon içerisindeki bilgi kaynaklarının bibliyografik niteleme alanlarının tanımlanması, konu başlıklarının verilmesi ve bu başlıklara yönelik sınıflama numaralarının oluşturulması şeklinde organizasyonunun yapılmasıdır. Bu organizasyona yönelik işlemlerin yürütülmesi de her meslek ve iş grubunda olduğu gibi birtakım etik ilkeler dahilinde yapılmalıdır. Kataloglama etiği, kütüphanecilik etiğinin ayrı bir alt disiplinini oluşturmaktadır. Ayrıca kataloglama etiği, kullanıcıların bilgi gereksinimlerine hizmet etme ve bilgi kaynaklarına erişim sağlama temel değerlerine dayanmaktadır. Bu çalışmada; kataloglama etiği kavramının bilimsel bakış açısı ile ele alınması amaçlanmıştır. Çalışmanın amacı doğrultusunda, kataloglama etik ilkelerinin neler olduğu ve kataloglama işlemlerinde katalogcuların nasıl davranması gerektiği belirtilmiştir. Diğer yandan kataloglama uygulamalarından örnekler verilerek etik ilkelerin uygulanmasında karşılaşılabilecek zorluklar ortaya konmuştur. Betimleme yönteminin kullanıldığı araştırmada, etik, mesleki etik ve kütüphanecilik etiği kavramları tanımlanmış, kataloglama etik ilkelerinin literatürde nasıl ele alındığı karşılaştırmalı olarak sunulmuş ve katalogcuların nelere dikkat etmesi gerektiği üzerinde durulmuştur. Çalışmanın amacına uygun olarak Ulusal Toplu Katalog (TO-KAT) üzerinden çeşitli katalog kayıtları incelenmiştir. Yapılan incelemelere göre aynı esere ilişkin katalog kayıtlarında özellikle farklı ve tutarsız konu başlıklarının kullanımı, farklı sınıflama numarasının verilmesi ve aynı kütüphane tarafından aynı esere ilişkin farklı katalog kayıtlarının oluşturulması gibi bulgular elde edilmiştir. Kataloglama etiği ve RDA kataloglama standartlarının ilişkisini temel alan ve literatüre dayalı yapılan bu çalışmada, elde edilen bilgiler doğrultusunda kataloglamada etik ihlallerden kaçınmak için önerilerde bulunulmuştur. Uluslararası literatürde kataloglamada ve sınıflamada etik yaklaşım konusunda pek çok çalışma bulunmaktadır. Fakat yerel literatür incelendiğinde kataloglama ve sınıflamada mesleki etik özelinde sınırlı sayıda çalışma olduğu tespit edilmiştir. Bu açıdan yapılan araştırma, özgün ve yerel literatürde konuyu tartışması açısından özgün bir çalışmadır.
CONHECIMENTO REVELADO NA ESCRITA REFLEXIVA DE FUTUROS PROFESSORES DE MATEMÁTICA DECORRENTE DE PLANEJAMENTOS DE AULAS EM UMA DISCIPLINA DE PRÁTICA DE ENSINO
Authors: Lima Rodrigues André , Rodrigo Teixeira Bruno
Published: December 2022

Neste artigo, tem-se por objetivo identificar subdomínios do Conhecimento especializado do Professor de Matemática relevados na escrita reflexiva de futuros professores, decorrente de planejamentos de aulas em uma disciplina de Prática e Metodologia do Ensino de Matemática, e evidenciar componentes desse contexto formativo que, possivelmente, colaboraram para a mobilização de tais conhecimentos. A fim de atingi-lo, foram analisadas escritas reflexivas a respeito das aulas destinadas a estudo e elaboração de planos de aula de três estudantes do quarto ano da Licenciatura em Matemática da Universidade Estadual de Londrina no ano letivo de 2019. Como resultados, evidenciaram-se mobilizações de subdomínios do Conhecimento especializado do Professor de Matemática e componentes do contexto formativo que possivelmente foram potenciais para isso, como a antecipação de possíveis dúvidas, erros e resoluções de alunos, estudo do conteúdo em livros didáticos, discussões com colegas de turma e com o formador. Além disso, os resultados obtidos revelam potencialidades da utilização da escrita reflexiva por parte de futuros professores de Matemática e da dinâmica de condução da disciplina para propiciar um ambiente oportuno à mobilização de conhecimentos profissionais docentes e ao seu desenvolvimento profissional. Tais resultados também podem orientar professores formadores em suas práticas e evidenciam a necessidade de valorização do conhecimento profissional docente, que é especializado e construído a partir de uma formação que assim o considere.
COMPREENSÕES DE PROFESSORAS SOBRE AS ESTRUTURAS ADITIVAS: IMPLICAÇÕES DO PNAIC PARA A FORMAÇÃO PROFISSIONAL
Authors: Giombelli Cirlei , Helena Cordeiro Maria
Published: December 2022

Neste artigo, apresentamos uma síntese de uma pesquisa desenvolvida no curso de mestrado em educação, com o objetivo de verificar se (e em que sentido) a formação do PNAIC contribuiu para aprimorar a compreensão das professoras sobre o processo de elaboração dos conceitos matemáticos realizado pelas crianças do ciclo de alfabetização do Ensino Fundamental assim como a qualidade da intervenção pedagógica das professoras. A pesquisa teve como aporte teórico a teoria dos campos conceituais de Gérard Vergnaud. Colaboraram na investigação 32 professoras que lecionavam no ciclo de alfabetização da rede municipal de uma cidade do oeste de Santa Catarina, metade das quais tinham participado das formações do PNAIC na área de matemática. As professoras foram organizadas em duplas para responderem a um instrumento composto por sete problemas de estruturas aditivas, de transformação, composição e comparação, respondidos por crianças no início do processo de escolarização. Além disso, responderam individualmente a um questionário para identificação de seu perfil sócio demográfico e profissional. As respostas das professoras foram analisadas em dois eixos: 1) compreensão dos aspectos conceituais dos problemas apresentados e 2) compreensões subjacentes às intervenções pedagógicas propostas por elas. Os resultados sugerem que a formação do PNAIC parece ter contribuído para uma maior consciência da necessidade de intervenção diante de possíveis erros e da necessidade de utilizar diferentes formas de representação, mas não foi suficiente para provocar significativos avanços conceituais no que se refere às estruturas matemáticas.
GEOMETRIA E PENSAMENTO GEOMÉTRICO NA FORMAÇÃO INICIAL DE PROFESSORES QUE ENSINAM MATEMÁTICA: O QUE REVELAM PESQUISAS BRASILEIRAS ENTRE 2009 E 2020
Authors: Caroline Cybulski Fernanda , de Costa Trindade Cyrino Márcia Cristina
Published: December 2022

"Este artigo tem por objetivo discutir abordagens a respeito do ensino de geometria na formação inicial de professores que ensinam matemática (PEM), assim como caracterizações de pensamento geométrico e principais aportes teóricos, presentes em teses e dissertações brasileiras publicadas entre 2009 e 2020. Para a constituição do corpus de análise foi realizado um mapeamento de dissertações e teses oriundas de Programas de Pós-graduação brasileiros Stricto Sensu, das Áreas de Educação e Ensino, na plataforma digital do Catálogo de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior e no catálogo da Biblioteca Digital Brasileira de Teses e Dissertações, totalizando 18 trabalhos. Observa-se que representações de figuras geométricas, como desenhos, construções em softwares e material manipulável, são frequentemente utilizadas para abordar geometria na formação inicial de PEM. Tais representações são exploradas para: identificar conceitos ou propriedades de forma perceptiva; resolver situações-problema; verificar ou estudar propriedades geométricas, provas e demonstrações. Nos últimos anos há uma crescente busca de discussões e caracterizações para pensamento geométrico, embora ainda sejam incipientes. Raymond Duval e Pierre van Hiele foram privilegiados como autores de referência nos trabalhos analisados. O ensino de geometria e o pensamento geométrico na formação inicial de PEM são temas ainda pouco investigados em dissertações e teses brasileiras. Discutir abordagens visuais articuladas com caraterizações de pensamento geométrico pode ser um campo fértil para o trabalho com a geometria na formação inicial de PEM"
"ALFABETIZACÃO E LETRAMENTO MATEMÁTICO: FALANDO DA MATEMACIA"
Authors: Marques Gomes Josiane , dos Santos Bernardi Lucí
Published: December 2022

"O artigo busca suscitar reflexões sobre a Matemática, a Alfabetização Matemática e Letramento Matemático, com foco no conceito de Matemacia, ressaltando os motivos para aprender e ensinar matemática. O aporte teórico tem ancora na Educação Matemática Crítica, que coloca em tela as discussões relativas à matemática e ao seu papel na sociedade, pensando a formação de indivíduos críticos e promotores de seu conhecimento, construindo uma cultura baseada no respeito e na diversidade, nos direitos humanos e na liberdade de expressão. A abordagem metodológica adotada caracteriza-se como uma pesquisa bibliográfica, com base em autores como Ubiratan D’Ambrósio, Ole Skovsmose, Magda Soares e Ocsana Danyluk. Salientamos que o processo de alfabetização matemática de um indivíduo pode levá-lo ao empoderamento na medida em que ele reorganiza sua visão sobre a sociedade e assume um papel ativo nas decisões sociais. De forma simultânea à alfabetização, precisamos desenvolver práticas de letramento que permitam efetivamente esse indivíduo ingressar no mundo letrado. Alfabetização e letramento são processos interdependentes e indissociáveis. Destacamos o conceito de Matemacia, que representa uma forma de letramento matemático, que provê o suporte matemático e lógico para o exercício de uma cidadania crítica, para que os indivíduos consigam participar de sua sociedade, usando seus conhecimentos matemáticos, permitindo que eles se posicionem de forma consciente em busca de uma sociedade justa e ética."
"ENTREVISTA: JHONY ALEXANDER VILLA-OCHOA Y SU ITINERARIO EN LA INVESTIGACIÓN DE MODELOS MATEMÁTICOS"
Authors: Souza de Alencar Edvonete , Meireles dos Santos Campeiro Flaviane
Published: December 2022

Não se aplica
Drug allergy evaluation in children with suspected mild antibiotic allergy
Authors: Kitsos Nikolaos , Cassimos Dimitrios , Trypsianis Grigorios , Xinias Ioannis , Roilides Emmanouil , Grivea Ioanna , Mantadakis Elpis , Mavroudi Antigoni
Published: December 2022

Background

Adverse antibiotic reactions caused by an immunological mechanism are known as allergic reactions. The percentage of reported antibiotic allergies is likely to differ from the one validated after a drug provocation test (DPT) with the culprit antibiotic. This study aimed to compare the percentage of children who were thought to be allergic to a certain antibiotic with those who have a true allergy, as confirmed by DPTs. We also validated Skin Prick Tests (SPTs) and Intradermal Tests (IDTs) by assessing their sensitivity and specificity, in diagnosing antibiotic allergies using DPT as the gold standard. Furthermore, we investigated epidemiological risk factors such as personal and family history of atopic disease and eosinophilia.

Methods

Children with a history of possible allergic reaction to an antibiotic underwent a diagnostic procedure that included: (1) Eosinophil blood count, (2) SPTs, (3) IDTs and (4) DPTs. The parameters were compared with Pearson's Chi-Square and Fisher's Exact Test. Several risk factors that were found significant in univariate analysis, such as personal and family history of atopic disease, and positive SPTs and IDTs were examined with multiple logistic regression analysis to see if they were related to a higher risk for a positive DPT.

Results

Semi-synthetic penicillin was the most common group of antibiotics thought to cause allergic reactions in this study. Overall, 123 children with a personal history of an adverse reaction to a certain antibiotic, were evaluated. In 87.8% of the cases, the symptoms had occurred several hours after administration of the culprit antibiotic. Both SPTs and IDTs had low sensitivity but high specificity. Moreover, they had a high positive predictive value (PPV). In contrast, eosinophilia was not recognized as a risk factor. Seventeen patients (13.8%) had a true antibiotic allergy, as confirmed by a positive DPT. A positive IDT was a strong predictor of a positive DPT, along with a positive personal and family history of atopy.

Conclusion

SPTs and IDTs are very reliable in confirming antibiotic allergy when found positive. A negative result of a SPT highly predicts a negative DPT. A positive IDT and a positive personal and family history of atopy were recognized as significant risk factors for antibiotic allergy.
Flavokawain A alleviates the progression of mouse osteoarthritis: An in vitro and in vivo study
Authors: Jing Shaoze , Wan Junlai , Wang Tianqi , He Zhiyi , Ding Qing , Sheng Gaohong , Wang Shanxi , Zhao Hongqi , Zhu Ziqing , Wu Hua , Li Wenkai
Published: December 2022

Osteoarthritis (OA) is one of the most prevalent chronic degenerative joint diseases affecting adults in their middle or later years. It is characterized by symptoms such as joint pain, difficulty in movement, disability, and even loss of motion. Moreover, the onset and progression of inflammation are directly associated with OA. In this research, we evaluated the impact of Flavokawain A (FKA) on osteoarthritis. In-vitro effects of FKA on murine chondrocytes have been examined using cell counting kit-8 (CCK-8), safranin o staining, western blot, immunofluorescence staining, senescence β-galactosidase staining, flow cytometry analysis, and mRFP-GFP-LC3 adenovirus infection. An in-vivo model of destabilization of the medial meniscus (DMM) was employed to investigate FKA’s effect on OA mouse. An analysis of bioinformatics was performed on FKA and its potential role in OA. It was observed that FKA blocked interleukin (IL)-1β-induced expression of inflammatory factors, i.e., cyclooxygenase-2 (COX2) and inducible nitric oxide synthase (iNOS) in chondrocytes. In addition, FKA also downregulated the catabolic enzyme expression, i.e., aggrecanase-2 (ADAMTS5) and matrix metalloproteinases (MMPs), and helped in the upregulation of the anabolic protein expression, i.e., type II collagen (Col2), Aggrecan, and sry-box transcription factor 9 (SOX9). Moreover, FKA ameliorated IL-1β-triggered autophagy in chondrocytes, and it was observed that the FKA causes anti-inflammatory effects by the mitogen-activated protein kinase (MAPK) and phosphoinositide-3-kinase/Akt/mammalian target of rapamycin (PI3K/AKT/mTOR) signaling pathways inhibition. The results of immunohistochemical analysis and microcomputed tomography from the in vivo OA mouse model confirmed the therapeutic effect of FKA. Finally, we assessed the anti-arthritic impacts of FKA by conducting in vivo and in vitro analyses. We concluded that FKA can be employed as a useful therapeutic agent for OA therapy, but the findings require needs further clinical investigation.
YH29407 with anti-PD-1 ameliorates anti-tumor effects via increased T cell functionality and antigen presenting machinery in the tumor microenvironment
Authors: Kim Dong Kwon , Synn Chun-Bong , Yang Seung Min , Kang Seongsan , Baek Sujeong , Oh Se-Woong , Lee Gyu-Jin , Kang Ho-Woong , Lee Young-Sung , Park Jong Suk , Kim Jae Hwan , Byeon Youngseon , Kim Young Seob , Lee Doo Jae , Kim Hyun-Woo , Park June Dong , Lee Sung Sook , Lee Ji Yun , Lee Jii Bum , Kim Chang Gon , Hong Min Hee , Lim Sun Min , Kim Hey Ryun , Pyo Kyoung-Ho , Cho Byoung Chul
Published: December 2022

Among cancer cells, indoleamine 2, 3-dioxygenase1 (IDO1) activity has been implicated in improving the proliferation and growth of cancer cells and suppressing immune cell activity. IDO1 is also responsible for the catabolism of tryptophan to kynurenine. Depletion of tryptophan and an increase in kynurenine exert important immunosuppressive functions by activating regulatory T cells and suppressing CD8+ T and natural killer (NK) cells. In this study, we compared the anti-tumor effects of YH29407, the best-in-class IDO1 inhibitor with improved pharmacodynamics and pharmacokinetics, with first and second-generation IDO1 inhibitors (epacadostat and BMS-986205, respectively). YH29407 treatment alone and anti-PD-1 (aPD-1) combination treatment induced significant tumor suppression compared with competing drugs. In particular, combination treatment showed the best anti-tumor effects, with most tumors reduced and complete responses. Our observations suggest that improved anti-tumor effects were caused by an increase in T cell infiltration and activity after YH29407 treatment. Notably, an immune depletion assay confirmed that YH29407 is closely related to CD8+ T cells. RNA-seq results showed that treatment with YH29407 increased the expression of genes involved in T cell function and antigen presentation in tumors expressing ZAP70, LCK, NFATC2, B2M, and MYD88 genes. Our results suggest that an IDO1 inhibitor, YH29407, has enhanced PK/PD compared to previous IDO1 inhibitors by causing a change in the population of CD8+ T cells including infiltrating T cells into the tumor. Ultimately, YH29407 overcame the limitations of the competing drugs and displayed potential as an immunotherapy strategy in combination with aPD-1.
Musical folklore as a tool for social-ecological change in the Colombian Caribbean
Authors: López-Angarita Juliana , Restrepo María del Pilar , Guzmán Katherine , Escobar Dairo
Published: December 2022

Large herbivorous fishes, such as parrotfishes, play a critical role in coral reef ecosystems by limiting the coverage of macroalgae. Yet, in the Colombian Caribbean, parrotfishes are being increasingly targeted for human consumption as the demand for fish increases with tourist numbers. The Colombian Caribbean is dominated by Afro-descendant communities, and music is a deeply rooted form of expression and communication. ‘Champeta’, the local music folklore, is heard at all times of day and danced continuously in the islands off the coast of Cartagena. We conducted a survey of local tourist and fisheries stakeholders to characterise the parrotfish fishery, and designed a contextualised awareness-raising campaign of the ecological role of parrotfish and the need for management in the Islands of the Corales del Rosario and San Bernardo National Park. In doing so, we test if Champeta could be used as a mechanism for social-ecological change in Caribbean coastal communities in the context of coral reef conservation. Locals were engaged in every aspect of the campaign, especially with the song, as the campaign was a process rooted in their culture, interests and idiosyncrasies. Surveys of restaurants illustrated the size of the fishery and the extent of misinformation surrounding the consumption of parrotfish by tourists. We found that both locals and tourists held misconceptions about the ecological role of parrotfish and were supportive of efforts to protect them.
Emerging MRI techniques for molecular and functional phenotyping of the diseased heart
Authors: Cheng Hai-Ling Margaret
Published: December 2022

Recent advances in cardiac MRI (CMR) capabilities have truly transformed its potential for deep phenotyping of the diseased heart. Long known for its unparalleled soft tissue contrast and excellent depiction of three-dimensional (3D) structure, CMR now boasts a range of unique capabilities for probing disease at the tissue and molecular level. We can look beyond coronary vessel blockages and detect vessel disease not visible on a structural level. We can assess if early fibrotic tissue is being laid down in between viable cardiac muscle cells. We can measure deformation of the heart wall to determine early presentation of stiffening. We can even assess how cardiomyocytes are utilizing energy, where abnormalities are often precursors to overt structural and functional deficits. Finally, with artificial intelligence gaining traction due to the high computing power available today, deep learning has proven itself a viable contender with traditional acceleration techniques for real-time CMR. In this review, we will survey five key emerging MRI techniques that have the potential to transform the CMR clinic and permit early detection and intervention. The emerging areas are: (1) imaging microvascular dysfunction, (2) imaging fibrosis, (3) imaging strain, (4) imaging early metabolic changes, and (5) deep learning for acceleration. Through a concerted effort to develop and translate these areas into the CMR clinic, we are committing ourselves to actualizing early diagnostics for the most intractable heart disease phenotypes.
Arachidonic acid is associated with dyslipidemia and cholesterol-related lipoprotein metabolism signatures
Authors: Li Fan , Wang Yu , Yu Huahui , Gao Xiaoqian , Li Linyi , Sun Haili , Qin Yanwen
Published: December 2022

Introduction

Abnormal lipoprotein metabolism is associated with a variety of diseases, cardiovascular disease in particular. Free fatty acids (FAs) and triglycerides (TGs) are the principal lipid species in adipocytes and are the major components of lipoproteins. However, in routine clinical laboratory testing, only the total plasma concentrations of FAs and TGs are typically measured.

Methods

We collected 965 individuals with hyperlipidemia plasma and clinical characteristics; high-throughput metabolomics permits the accurate qualitative and quantitative assessment of a variety of specific FAs and TGs and their association with lipoproteins; through regression analysis, the correlation between multiple metabolites and routine measured lipid parameters was found. Mice were fed a diet containing AA, and the concentrations of TC and TG in the plasma of mice were detected by enzyme method, western blot and qRT-PCR detected the protein and mRNA levels of cholesterol synthesis and metabolism in mice.

Result

Using LC-MS/MS identified eight free FA and 27 TG species in plasma samples, the plasma concentrations of free arachidonic acid (AA) and AA-enriched TG species were significantly associated with the plasma low-density lipoprotein-cholesterol, apolipoprotein B (ApoB), and total cholesterol (TC) concentrations after adjustment for age, sex, the use of lipid-lowering therapy, and body mass index. AA-rich diet significantly increased the plasma concentrations of TC and ApoB and the liver expression of ApoB protein and reduced the protein expression of ATP binding cassette subfamily G members 5 and 8 in mice.

Discussion

In this study, it was clarified that the plasma concentrations of free AA- and AA-enriched TG species were significantly associated with the plasma low-density lipoprotein-cholesterol, ApoB, and TC concentrations in individuals with hyperlipidemia, and it was verified that AA could increase the plasma TC level in mice. Taken together, these findings suggest a potential role of AA in the regulation of plasma cholesterol and lipoprotein concentrations.
Exploring the use of topological data analysis to automatically detect data quality faults
Authors: Tudoreanu M. Eduard
Published: December 2022

Data quality problems may occur in various forms in structured and semi-structured data sources. This paper details an unsupervised method of analyzing data quality that is agnostic to the semantics of the data, the format of the encoding, or the internal structure of the dataset. A distance function is used to transform each record of a dataset into an n-dimensional vector of real numbers, which effectively transforms the original data into a high-dimensional point cloud. The shape of the point cloud is then efficiently examined via topological data analysis to find high-dimensional anomalies that may signal quality issues. The specific quality faults examined in this paper are the detection of records that, while not exactly the same, refer to the same entity. Our algorithm, based on topological data analysis, provides similar accuracy for both higher and lower quality data and performs better than a baseline approach for data with poor quality.