bluuebunny/crossref_metadata_2025 huggingface dataset:
Factors associated with the need of Parenteral Nutrition in Critically Ill patients with Enteral Nutrition Therapy
Authors: Lopez-Delgado Juan C. , Grau-Carmona Teodoro , Bordeje-Laguna M. Luisa , Portugal-Rodriguez Esther , Lorencio-Cardenas Carol , Vera-Artazcoz Paula , Macaya-Redin Laura , Martinez-Carmona Juan Francisco , Marin-Corral Judith , Flordelis-Lasierra Jose L. , Seron-Arbeloa Carlos , Alcazar-Espin Maravillas de las Nieves , Navas-Moya Elisabeth , Aldunate-Calvo Sara , Martin-Luengo Ana , Nieto-Martino Beatriz , Gonzalez-Iglesias Carlos , Montejo-Gonzalez Juan C. , Servia-Goixart Lluis
Published: August 2022

Background: Enteral nutrition (EN) is the preferred route of nutrition in the critically ill patients. However, EN is not always able to provide optimal nutrient provision and parenteral nutrition (PN) is needed. We examined factors associated with the need of PN after start of EN, together with the use and complications associated with EN.Methods: Adult patients admitted to 38 Spanish intensive care units (ICUs) between April and July 2018, who needed EN therapy were included in a prospective observational study. The characteristics of EN-treated patients and those who required PN after start EN were analyzed.Results: Of a total of 443 patients, 43 (9.7%) received PN. One-third (29.3%) of patients presented EN-related complications, which were more frequent among those needing PN (26% vs. 60%, P=0.001). No differences regarding mean energy and protein delivery were found between patients treated only with EN and those needing supplementary or total PN. Abnormalities in lipid profile, blood proteins, and inflammatory markers, such as C-Reactive Protein, were showed in those patients needing PN. Sequential Organ Failure Assessment (SOFA) on ICU admission (Hazard ratio [HR]:1.161, 95% confidence interval [CI].1.053-1.281, P=0.003) and modified Nutrition Risk in Critically Ill (mNUTRIC) score (HR:1.311, 95% CI:1.098-1.565, P=0.003) were higher among those who needed PN. In the multivariate analysis, higher SOFA score (HR:1.221, 95% CI:1.057-1.410, P=0.007) and higher triglyceride levels on ICU admission (HR:1.004, 95% CI:1.001-1.007, P=0.003) were associated with an increased risk for the need of PN, whereas higher albumin levels on ICU admission (HR:0.424, 95% CI:0.210-0.687, P=0.016) was associated with lower need of PN.Conclusion: Higher SOFA and nutrition-related laboratory parameters on ICU admission may be associated with the need of PN after starting EN therapy. This may ultimately be related with the occurrence of gastro-intestinal dysfunction, severe inflammatory response, and disease severity. Trial registration: The Evaluation of Nutritional Practices In the Critical Care Patient (ENPIC) Study was registered at ClinicalTrials.gov (NCT03634943). Retrospectively registered on 17 August 2018.
D3 lymph node dissection with versus without left colic artery preservation in single-incision laparoscopic surgery for sigmoid and rectosigmoid cancer: a propensity score-matched analysis
Authors: Hiranuma Chikashi , Ishiyama Yasuhiro , Hirano Yasumitu , Hattori Masakazu , Doden Kenji
Published: August 2022

﻿PurposeIn surgery for colorectal cancer, dissection of the lymph nodes and fatty tissue around the root of the inferior mesenteric artery is important from an oncologic point of view. However, it is debatable whether it is better to preserve or remove the left colic artery (LCA). This study aimed to compare D3 lymphadenectomy with versus without LCA preservation in single-incision laparoscopic surgery for sigmoid and rectosigmoid cancer.MethodsA total of 1138 patients underwent surgery for colorectal cancer between April 2011 and December 2018 at Fukui Prefectural Hospital. This propensity score-matched retrospective study analysed the data of 163 patients: 42 patients with LCA preservation (group A) and 129 without LCA preservation (group B). Clinical and oncological outcomes were compared between the two groups.ResultsAfter propensity score matching, the mean ASA score was slightly lower in group B than in group A. There were no significant differences between groups A and B in surgical outcomes, including the 5-year overall survival rate (80% vs 80%, hazard ratio (HR) 1.11, 95% confidence interval (CI) 0.43–2.86), 5-year disease-free survival rate (76.6% vs 80%, HR 0.82, 95% CI 0.26–2.48), and 5-year cancer-specific survival rate (90% vs 83.3%, HR 1.29, 95% CI 0.34–5.23).ConclusionThere were no significant differences in the short- and long-term outcomes of patients who underwent single-incision laparoscopic surgery with D3 lymphadenectomy with versus without LCA preservation. This suggests that LCA preservation is safe and feasible in single-incision laparoscopic surgery for sigmoid and rectosigmoid colon cancer.
Influence of decision support persons on breast cancer treatment decisions among Latinas
Authors: Morales Krystal A. , Abrahamse Paul H. , Veenstra Christine M. , Jagsi Reshma , Hawley Sarah T. , Wallner Lauren P.
Published: August 2022

Purpose:Latinx experiences within cancer treatment decision-making remain largely understudied. We examined breast cancer treatment decision-making among Latina patients and their Latinx decision support persons (DSP).Methods:Women with newly diagnosed early-stage breast cancer (2014-2015) as reported to Surveillance, Epidemiology, and End Results (SEER) registries of Georgia and Los Angeles County, were surveyed (N=2502). Respondents identified the key DSPs in their treatment decisions, who were also surveyed (N=1203). Among 1,173 dyads, we examined: (1) bivariate associations of DSP characteristics with DSP-reported engagement, (informed about decisions, involvement (extent/satisfaction), and awareness of patient preferences), (2) DSP engagement with patient-reported subjective decision quality (SDQ) and treatment deliberation using multivariable linear regression, and (3) correlation between treatment received with DSPs treatment preferences.Results:Among Latina dyads (N=292), 78%, 17%, and 5% of DSPs identified as Latinx, White, and Asian/Black/Other, respectively. The key DSP for the Latina/Latinx dyads was more often a daughter (37%), over a husband/partner (21%) when compared to all other Latina/DSP and non-Latina/DSP dyads. Latinx DSPs also reported being more informed (p=0.058), and this was positively associated with higher patient SDQ (adjusted mean difference 0.176, p=0.034). Latinx DSPs also had a higher preference for mastectomy, especially with reconstruction compared to non-Latinx DSPs (40% vs 28%, p<.001).Conclusions:There are key differences in the characteristics and decision-making experiences among Latina patients when their DSP is also Latinx. This is important for clinicians to recognize, promote their inclusion, and meet their information needs, which our findings suggest positively impacts Latina SDQ.
Using an ocean culture course to improve students’ marine life concepts and learning interest
Authors: Hsieh Fu-Pei , Chen Yun-An , Tsai Chun-Yen
Published: August 2022

This study aimed to determine the effectiveness of an ocean culture course using the TRIP learning model (Triggered situational interest-Reading-Inquiry-Presentation) in enhancing students’ marine life concepts and learning interests. The participants consisted of 67 first graders (6 years old). A quasi-experimental design was employed, and the mixed methods analysis was used in this study. The results indicated that the experimental group students’ concepts of marine life were improved with a large effect size (d = 1.4), and they outperformed their counterparts with a large effect size (f = 0.40). The students’ learning interest in marine ecological conservation concepts was improved with a medium effect size (d = 0.53), and they outperformed their counterparts with a large effect size (f = 0.54). The results revealed that using the TRIP learning model for marine education improved the teaching of the teachers who taught the experiment group. Moreover, the model enhanced the effectiveness of the students’ learning interest in understanding marine life and marine ecological conservation concepts. Finally, some suggestions for further teaching and research were provided.
Comprehensive hemocompatibility analysis on the application of Diamond-like carbon to ePTFE artificial vascular prosthesis
Authors: Goyama Takashi , Fujii Yasuhiro , Muraoka Genya , Nakatani Tatsuyuki , Ousaka Daiki , Imai Yuichi , Kuwada Noriaki , Tsuji Tatsunori , Shuku Takayuki , Uchida Haruhito A. , Nishibori Masahiro , Oozawa Susumu , Kasahara Shingo
Published: August 2022

The aim of this study was to obtain comprehensive data regarding the hemocompatibility of diamond-like carbon (DLC)-coated expanded polytetrafluoroethylene (ePTFE). DLC increased hydrophilicity of the ePTFE surface and made ePTFE fibers smoother. DLC-coated ePTFE had more albumin and fibrinogen adsorption and less platelet adhesion than uncoated ePTFE. There were scarce red cell attachments in in vitro human and in vivo animal (rat and swine) whole blood contact tests in both DLC-coated and uncoated ePTFE. DLC-coated ePTFE had a similar but marginally thicker band movement than uncoated-ePTFE with SDS-PAGE after human whole blood contact test. In addition, survival studies of aortic graft replacement in rats (1.5 mm graft) and arteriovenous shunt in goats (4 mm graft) were performed to compare the patency and clot formation between DLC-coated and uncoated ePTFE grafts. Comparable patency was observed in both animal models. However, clots were observed in the luminal surface of the patent 1.5mm DLC-coated ePTFE grafts, but not in that of uncoated ePTFE grafts. In conclusions, hemocompatibility of DLC-coated ePTFE was high and comparable to that of uncoated ePTFE. However, it failed to improve the hemocompatibility of 1.5 mm ePTFE graft probably because increased fibrinogen adsorption canceled the other beneficial effects of DLC.
A Personalized Learning Theory-based Cyber-security Training Exercise
Authors: Chowdhury Nabin , Gkioulos Vasileios
Published: August 2022

Current enterprise needs for skilled cyber- security (CS) professionals have prompted the development of diverse CS training programs and of ferings. It has been noted however that even though enterprise staff is now more aware of security threats, the number of successful attacks against companies has all but decreased over the years. Several criticisms were raised against current CS training offerings, which often made them inadequate, or unable to change participants’ behaviour and security attitude. One of the main factors CS training programs are often not very effective is the lack of engagement or motivation of participants. This is often the result of training not being tailored to the needs or preferences of participants. In our previous work, we tackled this issue by developing a personalized learning theory-based model for developing CS training frameworks. In this work, we utilize the model to develop two CS training exercises: two game-based scenarios using the CS training video game CyberCIEGE and one table-top team exercise. The exercises are later tested by involving a group of 12 students from the Norwegian Institute of Science and Technology (NTNU) Information Security master’s degree program. According to the results of the experiment and the feedback from the students, students felt more engaged during the exercises due to having been participants in their development process. This has in turn motivated them to continue using the training tools independently in their spare time. Further research is recommended to establish whether the training development model is adequate for different target groups, as well as better performing than other models when developing full-fledged training programs.
Adaptive Convolutional Neural Network-based Speckle Removal From Undersampled K-space Data
Authors: Manimala MALLAVELLI V.R. , Naidu C Dhanunjaya
Published: August 2022

This paper presents the framework for accelerating MR Imaging (MRI) by adopting Compressive Sampling/Sensing (CS) strategy. The major drawback is the extensive time involved in recovering MR Images from the limited k -space data which is often affected by various noises. Specifically speckle noise is seen to affect medical imaging modalities like ultrasound and MR scanning. This work presents the mathematical analysis for the distribution that arises due to the Speckle scattering. Further, a method has been devised to eliminate the Speckle noise to reconstruct MR images from the sub-sampled k -space (spatial frequency) data, while preserving the visual quality. The proposed sparse reconstruction method constructs on a Deep Convolutional Neural Network (DCNN) to reduce the reconstruction time. The CNN training involves the pairs of images which are generated from sub-sampled noisy spatial frequency points and the corresponding fully sampled k -space data. The performance of the proposed method has been evaluated with various sub-sampling schemes. The results show a remarkable reduction in the computation time along with high image quality for various undersampling strategies.
Correlation Between Gene Polymorphisms and Levels of Serum Matrix Metalloproteinases with Cavitary Features and Pulmonary Fibrosis of the Patient Tuberculosis Multi-Drug Resistance Using High-Resolution Computerized Tomography of the Thorax
Authors: Messah Anse Diana Valentiene , Nugroho Christian Marco Hadi , Kurnia Ryan Septa , Silaen Otto Sahat Martua , Darmiati Sawitri , Rumende Cleopas Marthin , Soemarwoto Retno Ariza , Prihartono Joedo , Asmarinah Asmarinah
Published: August 2022

Matrix metalloproteinases (MMPs) are proteins that play a role in the inflammatory andremodeling processes caused by infections, including pulmonary tuberculosis (TB), especially multidrug resistance. This studyaims to correlate the relationship between serum levels and polymorphism of MMP-1 and MMP-9 with cavitycharacteristics, such as number, diameter, wall thickness as well as distribution of fibrosis in Multidrug-Resistant (MDR)- and Drug-Sensitive (DS)-TB patients. This study used a comparative cross-sectional study design. The subjects came from outpatients at Abdoel Moelok Hospital, Lampung Indonesia had passed the ethical test. Subjects were divided into two groups, 34 subjects in the MDR-TB group and 36 subjects in the DS-TB group. The levels of MMP-1 and MMP-9 were carriedout by ELISA test, genotype of MMP-1 and MMP-9 were determined using PCR-Sequencing method. In addition, cavities and fibrosis were measured using thoracic High-Resolution Computerized Tomography (HRCT) imaging. There was significant difference in the number of cavities more than 6, 6 mm in diameter, as well as cavity thickness in MDR-TB compared to DS-TB patients. Fibrosis distribution in lung segments was also different significantly in MDR-TB compared to DS-TB. Although MMP-9 levels in the MDR-TB group were highest than in the DS-TB group, there was no statistically significant. This study showed that there was a correlation between MDR-TB and DS-TB regarding the number of cavities, cavity diameter, cavity wall thickness, and distribution of fibrosis in the affected lung segments as measured by HRCT. There was no correlation between MMP-1 (-1607G) and MMP-9 (C1562T) genotypes and MMP-1 and MMP-9 serum levels, the MMP‑1 genotype in the two study groups differed significantly and was a risk factor for five times the incidence of MDR-TB. In addition, there was a substantial difference in cavity wall thickness between the G/G MMP-1 1607 genotype and the T/T MMP-9 genotype in the two study groups.
Collusive behaviour in the automobile sector in Spain. Quantifying consumer damages
Authors: Puente Adolfo C. Fernández , Sánchez-Sánchez Nuria
Published: August 2022

On July 23, 2015, the Spanish National Markets and Competition Commission passed judgement (S/0482/13) against 20 automotive sector companies for alleged restrictive competition practices between March 2004 and August 2013. The exchange of information among the different companies would have had repercussions on the fixing of vehicle sale prices, homogenization of conditions and future commercial plans for the automobile sale and post-sale services in Spain. This paper estimates the loss suffered by consumers as a result of these collusive practices using the Before and After method. We have reconstructed the prices that would have prevailed in the absence of the collusive practice. The analysis reveals an increase of 10.16 percent. The observation of the prices and the production of automobiles during the period exhibits an anomalous behaviour with respect to GDP evolution and prices in the economy as a whole.
Novel α-Bi 2 O 3 Nanoparticles with Significant Photocatalytic Activity for Methyl Orange and Ciprofloxacin removable
Authors: Balarabe Bachir Yaou , Paria Shashikana , Tetteh George Nii Tetteh , Baraze Abdoul Razak Ibrahim , Oumarou Maman Nasser Illiassou
Published: August 2022

The grinding method was successfully used to synthesize α-Bi2O3 Nanoparticles. The structural, and optical were performed using XRD, FT-IR, UV-Vis DRS, and Raman analysis. Based on the XRD and Raman data, we believed that the as-synthesized Bismuth Trioxide was monoclinic (α-Bi2O3) with a hexagonal structure. Furthermore, the EDXRF, as well as EDX results, reveal that the synthesized material is highly pure with less quantity of impurities.Under UV light, nanoparticles of Bi2O3 have a superior photocatalytic activity for Methylene Blue and Ciprofloxacin degradation. 87% of removable for Ciprofloxacin after 100minutes and 95% after 150min for Methyl Orange. The Total Organic Carbon (TOC) removal report shows that 67.73% of ciprofloxacin was removed after 200 min and 77.86% after 280 min for MO.
Survival of epithelial ovarian cancer in Black women: a society to cell approach in the African American Cancer Epidemiology Study (AACES)
Authors: Schildkraut Joellen M. , Johnson Courtney , Dempsey Lauren F. , Qin Bo , Terry Paul , Akonde Maxwell , Peters Edward S. , Mandle Hannah , Cote Michele L. , Peres Lauren , Moorman Patricia , Schwartz Ann G. , Epstein Michael , Marks Jeffrey , Bondy Melissa , Lawson Andrew B. , Alberg Anthony J. , Bandera Elisa V.
Published: August 2022

Purpose: The five-year relative survival for epithelial ovarian cancer (EOC) is worse among Black women compared with White women. The causes for this disparity are likely multi-factorial but unclear as to date, no cohort study has focused specifically on Black EOC survivors. Here we present the African-American Cancer Epidemiology Study (AACES), the largest cohort of Black women diagnosed with EOC. Methods: Phase 1 began in 2010 as a multi-site population-based case-control study focused on risk, and phase 2 began enrolling newly diagnosed EOC cases in 2020. Phase 2 builds on existing infrastructure with the goal to increase the number of EOC cases by 50% and evaluate factors affecting survival with a society-to-cell approach. Both phases use rapid case ascertainment to identify potential participants and collect extensive survey data, biospecimens, medical record abstraction, and annual follow-up.Results: Phase 1 enrolled 592 women with EOC, with a median survival of 4.8 years as of 2021. These survival rates approximate those of Black women in SEER who survive at least 10 months past diagnosis. A high proportion of the cohort was found to have relatively low levels of household income, education, and insurance coverage. Conclusions and Implications for Cancer Survivors: AACES is well-positioned to evaluate the contribution of social determinants of health to the poor survival of Black women with EOC, advance understanding of the multi-factorial causes of the ovarian cancer survival disparity in Black women, and serve as an example of a multi-site, epidemiologic population-based study of a rare cancer in a minority population.
High-security image encryption by multiplexing phase encoding in domains of dual optical transforms
Authors: Li Zhihui , Gao Bin , Pan Xiaoou , Wang Chenxuan , Zuo Weizhuo , Ji Yu , Liu Shutian , Liu Zhengjun
Published: August 2022

A novel optical image encryption is proposed based on multiplexing of the random phase encoding after shift and rotation operations in domains of extended fractional Fourier transform (eFrFT) and Fresnel transform. The original image is subjected to eFrFT with the action of the random phase mask. The mask is shifted and rotated. The image obtained from the fractional Fourier transform is entered into Fresnel diffraction by the use of the phase mask to obtain the final encrypted image. We design that the multiplexing operation of the phase keys can reduce the storage volume of the keys. Here, the displacement amount, rotation angle and wavelength in this system can be used as additional keys to improve the security and reliability of the encryption system. Numerical experiments are conducted to verify the effectiveness and security of the algorithm. The results show that the keys are very sensitive enough for high security.
Purification of 57kDa Hyaluronidase from the venom of Conus betulinus (Linnaeus, 1758)
Authors: Sivaramakrishnan Ramachandiran , Kanchana Shankar , Arumugam Muthuvel
Published: August 2022

The enzyme hyaluronidase cleaves the substrate hyaluronic acid. In the study, hyaluronidase was isolated from the venom gland of C. betulinus and characterised using SDS-PAGE, FTIR, and HPLC. The protein content of crude venom is approximately 4mg/ml, whereas purification with Sepacryl S-100 yielded 0.04mg/ml protein with 0.463TRU/mg specific activity. The detected hyaluronidase had a molecular weight of 57kDa when compared to a standard protein marker. The presence of a peak at Rt 57.23 as hyaluronidase is revealed by HPLC analysis, and the wavelength pattern is similar to the standard bovine testicular hyaluronidase.
Relating Enrique surface with K3 and Kummer through involutions and double covers over finite automorphisms on Topological Euler–Poincaré characteristics over complex K3 with Kähler equivalence
Authors: Bhattacharjee Deep , Roy Sanjeevan Singha , Behera Ashis Kumar
Published: August 2022

A segregated approach is used through several maps and classifiers where a study has been conducted to establish a concrete relational equivalence among several hypercomplex structures over three—order categorization tables namely ‘Enrique surface classification’ and ‘Enrique-K3-Complex(K3)-Kähler-Kummer surface characteristics’ with ‘K3– Complex(K3)-Kähler-Kummer(K3)-Kummer classifiers’ taking into account several notions of algebraic topology and algebraic geometry. This paper is the continuation of the previous preprint https://doi.org/10.21203/rs.3.rs-1635957/v1. For the Enrique 7—classifiers are considered namely I, II, III, IV, V, VI, VII.
Economic Globalisation and Inclusive Green Growth in Africa: Contingencies and Policy-Relevant Thresholds of Governance
Authors: Ofori Isaac K. , Figari Francesco
Published: August 2022

This study employs macrodata for 23 African countries to examine whether good governance interacts with economic globalisation (EG) to foster inclusive green growth (IGG). First, the study finds that EG hampers IGG in Africa. Second, although unconditionally good governance promotes IGG, only government effectiveness interacts with EG to foster IGG. Across the social and environmental sustainability dimensions of IGG, however, the effects differ substantially. Notably, while the EG-governance pathways yield remarkable environmental sustainability net gains, a modest harmful effect was observed for socioeconomic sustainability. Evidence from our threshold analyses also suggests that while government effectiveness is critical for propelling EG to promote IGG, across the social and environmental perspectives of IGG, it is investments in building frameworks and structures for corruption control and the rule of law that are crucial. Our results shed new light on IGG and have several implications for Agenda 2030 and Agenda 2063.JEL Codes: F18; F4; F6; F63; F64; H1; O55; Q01; Q56
MODEL PANEL DATA DALAM MENGANALISIS DETERMINAN PADA RETURN SAHAM DI INDONESIA: STUDI KASUS JAKARTA ISLAMIC INDEX
Authors: Ardana Yudhistira
Published: August 2022

As a potential investor, you should analyze the financial performance of a company. Several methods that can be used are Economic Value Added, Market Value Added, and Cash Value Added. This study aims to analyze the factors that affect stock returns in companies listed on the Jakarta Islamic Index using the panel data model. The independent variables used in this study are EVA, MVA, and CVA. While the dependent variable is stock returns. The results showed that all the variables used in this study, namely EVA, MVA, and CVA, influenced stock returns in companies listed in JII. This is evidenced by the probability value of less than 5% (0.014374 < 0.05). These variables have a percentage in influencing stock returns of 32.91%, while the remaining 67.09% is influenced by other variables outside the model used. Meanwhile, independently, it can be concluded that EVA and CVA have no significant effect and have a negative correlation with stock returns. Meanwhile, MVA has a significant and positive correlation.
ANALISIS FAKTOR KOMUNIKASI, KONSEP DIRI, DAN LINGKUNGAN KERJA TERHADAP KEPUASAN KERJA DENGAN METODE MIX METHOD PADA KARYAWAN BANK SYARIAH INDONESIA KCP TULUNGAGUNG SUDIRMAN
Authors: Parastika Familda Anggun , Hapsari Mega Tunjung
Published: August 2022

This research is motivated by the importance of employee performance because employees are the driving force for the company's success. Aims to test and analyze the effect of communication, self-concept, and work environment on job satisfaction of employees of Bank Syariah Indonesia KCP Tulungagung Sudirman. The method used is a mix method with the type of research that combines quantitative and qualitative analysis (Sequantial Explanatory). The sample in this study were 27 employees of BSI KCP Tulungagung. Quantitative data multiple linear analysis test and hypothesis test. Qualitative data analysis using triangulation. Based on the research, partial results were obtained and communication stimulants, self-concept, and work environment had a positive effect on job satisfaction of employees of Bank Syariah Indonesia KCP Tulungagung Sudirman. To strengthen quantitative research, qualitative analysis was carried out by interviewing 6 informants whose results supported the results of quantitative data. Practical implications apart from developing research with mixed methods in human resource management, the research results can be used as recommendation materials to assess employee performance.
STRATEGI PENGELOLAAN ZIS PADA MUSIM PANDEMI COVID-19 (STUDI PADA BAZNAS SIDOARJO)
Authors: Hariyanti Sri , Rahmawati Suhaela
Published: August 2022

ZIS stands for Zakat, Infaq, and Shadaqah, for its management is officially carried out by BAZNAS or the National Amil Zakat Agency because this institution is the official and only body established by the government based on Presidential Decree No. 8 of 2001 which has the task and function of collecting and distributing zakat, infaq, and alms (ZIS) at the national level. However, at the beginning of 2020 ZIS management activities underwent a slight change due to the Covid-19 pandemic which caused social activities to be limited and the economic decline in Indonesia. Because of this in this article, we will focus on discussing how to manage ZIS strategies during the COVID-19 pandemic study season. at BAZNAS Sidoarjo. The research method used is descriptive qualitative, namely the research method used to investigate, find, describe and explain the quality or features of social influences that cannot be described, measured or described through a quantitative approach. The results of this study include making it easier for people to pay zakat/infaq and shadaqah at BAZNAS Sidoarjo using barcodes that can be paid through online payment applications such as gopay, ovo, link aja, funds, or other merchants/banks. As for the distribution, BAZNAS gave an invitation to Mustahiq to come to the BAZNAS office in stages, so as not to cause crowds and required to always implement health protocols.
Specific Changes in Hemostasis System Parameters during Extracorporeal Membrane Oxygenation in Patients with a Novel Coronavirus Infection
Authors: Zhuravel S. V. , Ivanov I. V. , Talyzin A. M. , Klychnikova E. V. , Bulanov A. Yu. , Popugaev K. A. , Vladimirov V. V. , Tazina E. V. , Petrikov S. S.
Published: August 2022

Extracorporeal membrane oxygenation (ECMO) is a method that makes it possible to compensate for critical changes caused by acute respiratory failure, with the ineffectiveness of treatment with rigid modes of artificial lung ventilation (ventilator) in patients with acute respiratory distress syndrome in intensive care units. The search for the optimal state of the hemostasis system is one of the main tasks in the treatment of critical patients in ECMO conditions.

The objective: to study changes in hemostatic parameters in patients with COVID-19 undergoing ECMO and determine the need for their correction.

Subjects and Methods. According to the inclusion and exclusion criteria, 100 patients were included in the study: 72 men and 28 women aged 26 to 75 years old, the median age made 55 years [47; 60]. VV-ECMO was performed in all observations. In 100% of cases, the cause of respiratory failure which required VV-ECMO was COVID-19-associated pneumonia.

Results. 49 episodes of hemorrhagic complications and 76 episodes of thrombotic complications were recorded from the 1st to the 7th day from the moment of ECMO initiation. We found that the chance of developing thrombosis decreased by an average of 0.3% with an increase in the activity of antithrombin-3 by 1%. A statistically significant association of thrombosis risk was also found for prothrombin and prothrombin time.

Conclusion. During the first 7 days of ECMO, patients with COVID-19 demonstrate the increase in APTT, prothrombin time and a decrease in the number of platelets, prothrombin activity, and fibrinogen concentration. The risk of thrombosis in this group of patients significantly decreases with the increasing activity of antithrombin-3 and prothrombin and increases with rising need of the higher dose of unfractionated heparin. The tactics of restrictive anticoagulant therapy when using unfractionated heparin can be taken into account as a way to reduce the risk of thrombosis and requires further research.
Levosimendan Hemodynamic Effects Depending on the Outcome of Sepsis
Authors: Tyurin I. N. , Protsenko D. N. , Kozlov I. A.
Published: August 2022

The objective: to study hemodynamic and clinical effects of levosimendan depending on the clinical outcome in patients with sepsis and impaired cardiac pumping function.

Subjects and Methods. the retrospective study involved 31 patients of 52.7 ± 2.8 years old with sepsis or septic shock which were treated with levosimendan at the dose of 0.16 [0.15‒0.17] mg/kg (0.11 [0.1‒0.12] μg × kg-1 × min-1) on days 1–4 of ICU stay. The patients were divided into the following groups: Group 1 ‒ survivors (n = 19) and Group 2 – non-survivors (n = 12). Central hemodynamics was assessed through transpulmonary thermodilution. The differences were considered statistically significant at p < 0.05.

Results. Most of the hemodynamic parameters and vasopressors and inotropes doses had no differences between the groups before levosimendan administration. There were no differences in the cardiac index (3.8 ± 0.3 vs 3.5 ± 0.3 L/min/m2; p = 0.479) between the groups following levosimendan administration, however, Group 1 demonstrated the following parameters to be lower versus Group 2: central venous pressure (7 ± 0.7 vs 11 ± 1 mm Hg; p = 0.005), blood lactate (1 [0.9‒1.8] vs 2.4 [2.2‒3.3] mmol/L; p = 0.04), norepinephrine dosages (0.2 [0.15‒0.35] and 0.5 [0.4‒0.6] ng/kg/min; p = 0.023 ), global end-diastolic volume index (693 [688‒28] vs 870 [779‒961] mL/m2; p =0,0009) and the level of NT-proBNP (1,590 [1,080‒3,160] vs 35,000 [21,400‒35,000] pg/mL; p = 0,0001). Global heart ejection fraction (23 [21‒27] vs 15 [12‒20]%; p = 0.015) and heart function index (6 [5‒8] vs 3 [ 3-4] min-1; p = 0.003) ) were higher in Group 1 versus Group 2. APACHE II >19 (AUC 0.906; p < 0.0001), SOFA > 9 (AUC 0.805; p = 0.0002); heart rate > 114 min-1 (AUC 0.755; p = 0.0095), and index of total peripheral vascular resistance < 1,700 dyn × s × cm-5 × m2 (AUC 0.806; p = 0.001) before levosimendan administration were the independent predictors of death in patients treated with levosimendan.

Conclusion: non-survivors patients with sepsis had significantly higher APACHE II and SOFA scores, higher heart rate and lower index of total peripheral vascular resistance before levosimendan infusion. In survivors levosimendan infusion at a standard dose led to a significant improvement in the heart pumping function accompanying by global heart ejection fraction and heart function index increasing and NT-proBNP decreasing. In non-survivors such favorable central hemodynamics changes did not occur, although the cardiac index increased after inodilator administration. Further studies of levosimendan efficacy in patients with sepsis of varying severity are advisable. It is necessary to specify the indications and contraindications for levosimendan administration to patients with sepsis.
Prospects for the Use of NGAL and KIM-1 for the Diagnosis of Acute Kidney Injury in Patients Receiving Antibacterial Therapy
Authors: Nikitin E. Yu. , Drozdov V. N. , Vyzhigina M. A. , Vorobieva O. A. , Astapovskiy A. A. , Khalaidzheva K. N. , Shikh E. V.
Published: August 2022

The developers of Clinical Practice Guidelines for Acute Kidney Injury titled The Initiative to Improve Global Kidney Disease Outcomes (KDIGO) point at the need of new biomarkers for diagnosis acute kidney injury (AKI).

The objective: to study and evaluate the diagnostic significance of the levels of neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) in patients with AKI in the early postoperative period when antibiotic therapy is used.

Subjects and Methods. AKI frequency was assessed in 276 patients during the early postoperative period after the antibacterial drugs had been prescribed. Serum levels of KIM-1 and NGAL, glomerular filtration rate (GFR), creatinine, protein in urine were tested before the start of antibiotic therapy, in 24–48 hours, and in patients with AKI – additionally in 72–96 hours. The normal initial renal excretory function was registered only in 36 patients (13.04%). The majority of patients (242 patients, 86.96%) were diagnosed with chronic kidney disease of various stages.

Results. NGAL and KIM-1 levels were higher in the group of patients with AKI before start of antibiotic therapy versus the group of patients with preserved renal function. However, a statistically significant increase in the level of KIM-1 and NGAL was found only in the group of patients with stages 3A and 3B of CKD versus the groups of patients with stages 1 and 2 of CKD. The second important observation is that a comorbid pathology in patients led to a high AKI incidence when antibiotic therapy was used – 35.86% (30–42%; 95%CI).

Conclusion. The relationship of NGAL and KIM-1 levels with glomerular filtration rate (GFR) and KIM-1 level with the presence of proteinuria as indicators of impaired renal filtration function suggests that NGAL and KIM-1 levels reflect the state of renal filtration function. Based on this observation, it should be accepted that NGAL and KIM-1 levels can be used as markers for the diagnosis of AKI in patients receiving antibiotic therapy. The prescription of antibiotic therapy in the postoperative period in patients with surgical pathology and renal dysfunction leads to a high AKI incidence. Elevated KIM-1 and NGAL levels in AKI during the antibiotic therapy suggests their involvement in the reparation process.
Gluon condensates and effective gluon mass
Authors: Horak Jan , Ihssen Friederike , Papavassiliou Joannis , Pawlowski Jan M. , Weber Axel , Wetterich Christof
Published: August 2022

Lattice simulations along with studies in continuum QCD indicate that non-perturbative quantum fluctuations lead to an infrared regularisation of the gluon propagator in covariant gauges in the form of an effective mass-like behaviour. In the present work we propose an analytic understanding of this phenomenon in terms of gluon condensation through a dynamical version of the Higgs mechanism, leading to the emergence of color condensates. Within the functional renormalisation group approach we compute the effective potential of covariantly constant field strengths, whose non-trivial minimum is related to the color condensates. In the physical case of an $SU(3)$ gauge group this is an octet condensate. The value of the gluon mass obtained through this procedure compares very well to lattice results and the mass gap arising from alternative dynamical scenarios.
Zjawisko a rzeczywistość – wpływ poglądów Bertranda Russella na koncepcję wielości rzeczywistości Leona Chwistka
Authors: Femiak Tomasz
Published: August 2022

W artykule omówione zostały główne publikacje Bertranda Russella z lat 1905-1921 jako stanowiące inspirację dla powstania teorii wielości rzeczywistości Leona Chwistka. W ten sposób ukazano tło historyczne, tj. wpływ podnoszonych przez Russella zagadnień na postawę badawczą Chwistka (jedna z wielu składowych sytuacji problemowej, w której teoria wielości rzeczywistości była tworzona). Artykuł zawiera także zestawienie poglądów obu filozofów oraz ocenę podobieństw i różnic między nimi.

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Zgłoszono: 28/03/2022. Zrecenzowano: 03/05/2022. Zaakceptowano do publikacji: 11/06/2022.
Rozwój teologii ekologicznej w Polsce. Od teoekologii do ekoteologii
Authors: Małek Krzysztof
Published: August 2022

W artykule zaprezentowana została ekoteologia jako jeden ze stosunkowo nowych obszarów badawczych w polskiej teologii. Celem artykułu jest wskazanie zakresu prowadzonych badań oraz dalszych możliwości ich rozwoju. W pierwszej części przedstawiono historię rozwoju dyscypliny. Druga część zawiera biblijne podstawy wskazane przez ekoteologów. W trzeciej części zaprezentowane zostały wypracowane definicje dyscypliny, w tym również zaproponowano nowe, autorskie jej określenie. W zakończeniu wskazano luki w omawianym obszarze badawczym oraz możliwości ich zapełnienia. --------------------- Zgłoszono: 06/12/2021. Zrecenzowano: 21/02/2022. Zaakceptowano do publikacji: 29/04/2022.
Pogańscy bogowie nieświadomości. Przed-filozoficzna myśl grecka a koncepcja polimorficznego umysłu w psychologii głębi
Authors: Sawicki Michał , Kowalski Arian
Published: August 2022

Niniejszy tekst podejmuje kwestię bogów i bohaterów mitów greckich, odnosząc ją do obecnej w psychologii głębi koncepcji archetypów i nieświadomości zbiorowej. Główny cel badań sprowadza się tym samym do bacznego przyjrzenia się potencjalnej korelacji pomiędzy zewnętrznymi (względem „ja”) w rozumieniu starożytnego Greka postaciami bogów i bogiń (wpływających na niego podobnie jak na bohaterów homeryckich), a wewnętrznymi przejawami nieświadomości zbiorowej, które mogą stanowić – według Carla Gustava Junga – istotę antycznych bóstw. Ponadto został poddany namysłowi problem wpływu „wewnętrznych bogów” na sposób myślenia, odczuwania i działania jednostki, wpływu zarówno pozytywnego, jak i negatywnego. Wynikająca z przeprowadzonych badań konkluzja zwraca uwagę na wartość sfery irracjonalnej – źródła pochodzenia zapomnianych, politeistycznych bogów, zamieszkujących psychikę współczesnego człowieka.

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Zgłoszono: 14/04/2022. Zrecenzowano: 11/05/2022. Zaakceptowano do publikacji: 30/05/2022.
Sprawozdanie z 21. sympozjum filozoficznego z cyklu "Filozofia dla teologów", Instytut Teologiczny im. św. abp. Józefa Bilczewskiego Archidiecezji Lwowskiej – Instytut Filozofii UKSW w Warszawie, Lwów – Warszawa, 9.04.2022 r.
Authors: Kobyliński Andrzej
Published: August 2022

9 kwietnia 2022 roku w Instytucie Teologicznym im. św. abp. Józefa Bilczewskiego Archidiecezji Lwowskiej zorganizowano 21. edycję sympozjum pt. "Filozofia dla teologów". Sympozjum zostało przygotowane we współpracy z Instytutem Filozofii Uniwersytetu Kardynała Stefana Wyszyńskiego w Warszawie. W trakcie sympozjum wygłoszono sześć referatów oraz dyskutowano nad ich treścią.
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Zgłoszono: 23/04/2022. Zrecenzowano: 13/05/2022. Zaakceptowano do publikacji: 09/06/2022.
Wavelet Transform Processing in Detecting Failures in Offshore Well Production
Authors: Esposte Coutinho Priscila , Haringer Martins da Silveira Larissa , Cataldi Marcio , Rodrigues Leta Fabiana , Orestes de Salvo Castro Antônio , Benevenuto de Campos Lima Cláudio , Brito Alves Lima Gilson
Published: August 2022

Brazil has a significant offshore oil production, which dates back to the late 1960s and is currently focused on exploring pre-salt reservoirs. The drilling technology Petrobras uses is considered a world standard: in 2020, it allowed offshore production to reach 97% of the country’s total oil production. During the process, however, unwanted events, and even operational failures may occur, which are capable of significant damage. Thus, failure detection is extremely important to prevent production losses or delays, to reduce costs and to avoid accidents. This study uses a real, public database on offshore production, and proposes using wavelet transforms to detect production failures. With the technique, we pinpointed which time intervals between measurements showed relevant variability, and then clustered the data, according to mobile averages, to shrink the record number. Using wavelet transforms, we analyzed which variables could be used as predictors of production failures and identified the temperature read by the Temperature and Pressure Transducer sensor (T-TPT) and the pressure at the Production Choke sensor (P-PCK) as possible predictor variables. We also observed the creation of a filtered series, averaged from the original data series, which maintained its variability, showing the viability of record regrouping in shorter series.
Gerenciamento de riscos em uma fábrica de móveis: um estudo de caso
Authors: Xavier Thiago Padovani
Published: August 2022

A indústria moveleira no Brasil possui pouco mais de 20 mil fábricas e, apesar de sua importância para a economia, enfrenta problemas relacionados diretamente com a baixa produtividade e diminuição da competitividade. Quando se fala em baixa produtividade e necessidade de manter o negócio, o gerenciamento de riscos e o mapeamento de processos surgem como ferramentas que podem auxiliar uma organização nestes aspectos. Existem várias técnicas de gerenciamento de riscos e estudos sobre o tema em indústrias de móveis já foram realizadas. Entretanto, as técnicas apresentam limitações que devem ser consideradas. Neste trabalho, foi realizado um estudo em uma indústria moveleira no norte do Espírito Santo que classifica os riscos de acordo com suas probabilidades e impacto e, a partir desta classificação, foi utilizado uma matriz de risco para determinar o grau dos riscos estudados e propor medidas de controle para minimizá-los. Contudo, este trabalho teve como objetivo a realização de mapeamento dos riscos em uma empresa do ramo moveleiro e propor ações em que houvesse o desenvolvimento de uma metodologia de gerenciamento de riscos utilizando o mapeamento de processos, podendo ao final, a empresa ter uma metodologia complementar as que já existem e pratica, e podendo ser aplicada e adaptada para outros setores da empresa.
A New Year, Newfangled COVID-19 Variant B.1.640.2 (IHU): What We
Know So Far?
Authors: Mukherjee Sukhes , Ray Suman Kumar
Published: August 2022

A new COVID-19 variant that no one currently wants has emerged with the start of the new
year. Omicron, which was first discovered in November of last year, was only just beginning to be
understood when another strain uncovered in France made headlines. On January 4, 2022, news of the
variant exploded on social media, but cases of what is now known as variant B.1.640.2 (IHU) were
initially discovered about two months prior. Evidence is still being gathered, but internet misinformation
regarding the latest coronavirus variety is already rampant, as it was with Omicron. The majority
of existing vaccines target SARS-spike CoV-2's protein, which the virus utilizes to enter and infect
cells. Epidemiologists and virologists worldwide are concerned about the virus' spike protein, which
plays a key role in how your body identifies and reacts to the virus. Spike proteins are produced, recognized,
and defended against by our immune system. Your body and the vaccines you have had
injected into your system have a far harder time fighting the virus when the amino acids in a protein
are altered or removed.
Do People Desire to Cycle More During the COVID-19 Pandemic? Investigating the Role of Behavioural Characteristics through a Structural Model
Authors: Rashidi Mahdi , SeyedHosseini Seyed-Mohammad , Naderan Ali
Published: August 2022

Background:

Most cycling behaviour studies have defined it using objective variables and focused on normal conditions.

Objective:

This study applies latent class analysis to a sample of 375 survey respondents in Tehran, the Capital city of Iran, exploring the variables influencing cycling behaviour during pandemic covid-19.

Methods:

We made a statistical comparison among the data obtained from the questionnaires and the statistical data of the 2016 census. A structural equation modeling (SEM) was developed.

Results:

Fourteen indicators define three latent variables. Cycling behaviour is defined by these three latent factors and three indicators. This paper goes through each of the indicators and their impact on latent variables. The findings show that latent factors have a direct impact on cycling behaviour.

Conclusion:

Structural equation modeling (SEM) is a great tool for defining cyclist behaviour analysis that shows the positive and negative influence of variables on cycling rate during a covid-19 pandemic. There are some limitations in the area of this study in developing countries discussed in the paper.
A Review on Aerosol Drug Delivery: Fundamentals, Classifications, Particle
Size Analysis and the Engagement of Nanoparticulate Systems
Authors: Mneimneh Amina Tarek , El-Maradny Hoda Ahmed
Published: August 2022

Background:

The pulmonary route of administration has shown viability and effectiveness in local and systemic delivery, as a non-invasive method, not only for active pharmaceutical ingredients but also for genes, proteins, and enzymes for pulmonary and non-pulmonary diseases.

Objectives:

Nanoparticulate systems such as liposomes, solid lipid nanoparticles, nanostructured lipid carriers, emulsions, nanosuspensions, polymeric nanoparticles, and metal-based have been investigated as delivery carriers for the lungs. Nanoparticulate drug delivery systems are known for their optimum small size and suitability for pulmonary absorption as it is well recognized that drug particles within the size range of 1–5 μm are the best for pulmonary deposition.

Results:

The advantages of these colloidal systems are generated by their small size, large surface area, and rapid absorption. These systems are characterized by ease of preparation as inhalable formulation, the ability to increase drug concentration at the site of disease, preventing and minimizing drug loss and degradation, and the possibility of cell targeting.

Conclusion:

This article provides a brief review of the features of different aerosol devices, their advantages, limitations, and methods utilized for particle size analysis with a focus on the emerging field of nanocarriers as vehicles for pulmonary delivery for various lung disorders.