bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of Cuticular And Web Lipids of The Spider Argiope Bruennichi
Authors: GERBAULET MORITZ , MÖLLERKE ANTON , WEISS KATHARINA , CHINTA SATYA , SCHNEIDER JUTTA M. , Schulz Stefan
Published: September 2021

Emerging evidence shows that the cuticular and silk lipids of spiders are structurally more diverse than those of insects, although only a relatively low number of species have been investigated so far. As in insects, such lipids might play a role as signals in various context. The wasp spider Argiope bruennichi has probably the best investigated chemical communication system within spiders, including the known structure of the female sex pheromone. Recently we showed that kin-recognition in A. bruennichi is mediated through the cuticular compounds consisting of hydrocarbons and to a much larger proportion of wax esters. By use of MS and various derivatization methods these esters were identified here to be esters of 2,4-di­methyl­alkanoates with varying chain length and 1-alkanols, such as tetradecyl 2,4‑di­methyl­hepta­decanoate. A representative enantioselectively synthesis to this compound was performed which proved the identifications and allowed to postulate the natural enantiomer to have (2R,4R)-configuration. Cuticular profiles of the silk and cuticula of females were similar, while male cuticular profiles differed quantitatively from those of females. In addition, minor female specific 4-methylalkyl esters were detected.
Development of a Quantitative Method to Evaluate Pedicle Screw Loosening After Spinal Instrumentation Using Digital Tomosynthesis
Authors: Mataki Kentaro , Hara Yuki , Okano Eriko , Nagashima Katsuya , Noguchi Hiroshi , Shibao Yosuke , Miura Kousei , Takahashi Hiroshi , Funayama Toru , Koda Masao , Yamazaki Masashi
Published: September 2021

BackgroundIn general, the diagnosis of pedicle screw (PS) loosening is evaluated qualitatively based on the presence of a radiolucent area around the implant wider than 1 mm on plain radiographs and computed tomography (CT). Digital tomosynthesis is a novel imaging technology that can acquire reconstructed tomographic images of patients in different postures with relatively low radiation. In this study, PS loosening is evaluated quantitatively by measuring the PS displacement angle in the vertebrae using digital tomosynthesis. MethodsWe evaluated 41 patients who underwent posterior spinal fusion surgery using PS. The 72 pedicle screws at the cranial end of the fused segments were evaluated. The patients were divided in two groups, one with PS loosening (7 patients, 12 screws) and the other without PS loosening (34 patients, 60 screws), based on conventional CT findings. All patients underwent tomosynthesis in two different postures during a single CT session. ResultsThe displacement angles of the PS in patients in a lying position and in a standing position were measured using selected slices of the same cross-sectional view from digital tomosynthesis. The displacement angle was significantly greater in the PS loosening group (5.7°) than in the group without PS loosening (0.6°) (p＜0.01). Based on the ROC analysis, the optimal cut-off value of the PS displacement angle for identification of loosened screws was 1.7° with a sensitivity of 100% and specificity of 93% (AUC=0.98). ConclusionsThis new method using digital tomosynthesis has the potential to aid diagnosis of PS loosening quantitatively and more accurately than conventional evaluations.
Interactive Effects of Meteorological Factors and Particulate Pollutants on Childhood Asthma: A Time Series Analysis in Shanghai, China
Authors: Hu Yi , Wu Dan , Hu Yabin , Li Shenghui , Liu Shijian , Tan Jianguo , Yin Yong , Yan Chonghuai , Wang Xiaolei , Lu Hui , Yu Guangjun , Tong Shilu
Published: September 2021

Background: Previous studies have revealed that meteorological factors or ambient air pollutants were associated with childhood asthma, but their interactive effects are scarcely known. Methods: In order to investigate the potential interactions between meteorological factors and air pollutants on childhood asthma, we obtained daily data on meteorological factors (mean temperature, mean relative humidity, and mean air pressure), air particulate matter (PM) with diameter < 2.5 µm (PM2.5) and < 10 µm (PM10), and outpatient visits for childhood asthma during 2007-2017 in Shanghai, China. Independent effects of meteorological factors and PM on childhood asthma were estimated using distributed lag non-linear model (DLNM), and then relative excess risk due to interaction (RERI) was calculated to assess their potential interactions. Results: A total of 976, 350 outpatient visits for childhood asthma were included in this study. Significant lagged and non-linear effects of meteorological factors and PM exposure on childhood asthma were observed in DLNM analyses. Further, in interaction analysis, we found statistically significant antagonistic interaction between mean temperature and PM (RERI: -0.14, 95%CI: -0.15, -0.12 for PM2.5; RERI: -0.09, 95%CI: -0.10, -0.08 for PM10) and synergistic interaction between mean air pressure and PM (RERI: 0.16, 95%CI: 0.14, 0.18 for PM2.5; RERI: 0.17, 95%CI: 0.15, 0.19 for PM10) on childhood asthma. Subgroup analyses by sex and age as well as sensitivity analyses of alternative degree of freedoms for calendar time, meteorological factors and PM are performed and confirmed the robustness of our results. Conclusion: Our findings provide supporting evidence that meteorological factors and PM might interactively affect childhood asthma, including antagonistic interaction between temperature and PM and synergistic interaction between air pressure and PM.
Critical Time Intervention to Facilitate Exiting Sex Work: Lessons Learned From a Fidelity Assessment
Authors: Perri Melissa , Shareck Martine , Buhariwala Pearl , Hassan Maha , O’Campo Patricia
Published: August 2021

IntroductionIndividuals who engage with sex work face barriers to maintaining overall health and well-being such as criminalization, stigmatization, and violence. An emerging approach to facilitating exiting sex work for individuals is through programs applying the Critical Time Intervention (CTI) model. CTI represents a time-limited practice that supports vulnerable individuals during periods of transition. The objectives of this study were to apply an existing CTI fidelity assessment to the sex work exiting program Exit Doors Here (EDH) to (1) report on the program’s fidelity and (2) discuss the effectiveness of CTI for supporting these groups. MethodsTo determine the applicability to the EDH of an existing fidelity assessment tool, we consulted with program staff through in person meetings. Staff highlighted areas for adaptation. We adapted the tool based on this feedback and used it to assess program fidelity by analyzing data from 8 participants’ CTI notes. Fidelity ratings were computed and interpreted according to established guidelines. ResultsConsultations with program staff resulted in adaptations to seven items out of the 12 comprising the fidelity assessment tool. The majority of adaptations surrounded the time-limited nature of CTI and unique needs of the program participants. In regards to the fidelity assessment using the adapted tool, half of the items were ideally implemented, one was well implemented, one was fairly implemented and two were respectively found to be poorly implemented and not implemented at all. Conclusions Difficulties in implementing selected program components with high fidelity can be attributed to specificities of the target population and to contextual factors, which are hard to control from a staff and program standpoint. This assessment reiterates the importance of considering such factors when developing and implementing programs aimed at improving the health and well-being of marginalized women such as those who engage in sex work.
Elevated gamma-glutamyl transferase has a non-linear association with incident non-alcoholic fatty liver disease in the non-obese Chinese population: a secondary retrospective study
Authors: Wu Liling , Zhang Man , Hu Haofei , Wan Qijun
Published: August 2021

Background

Effective and applicable predictors of non-alcoholic fatty liver disease (NAFLD) are needed for the non-obese Chinese population. We investigated whether serum gamma-glutamyl transferase (GGT) was associated with incident NAFLD in the non-obese Chinese population.
Methods

This was a retrospective cohort study that enrolled a total of 33153 initially NAFLD-free individuals who underwent a health examination in Wenzhou Medical Center of Wenzhou People’s Hospital from January 2010 to December 2014. We determined the relationship between GGT at enrollment and incident NAFLD during follow-up in 11906 persons. The relationship between GGT levels and incident NAFLD was analyzed using Cox regression and generalized additive models after adjustment for demographic and clinical variables. In addition, we also performed a subgroup analysis, which was explored by Cox proportional hazard models. It was stated that the data had been downloaded from the DATADRYAD website.
Result

Multivariable Cox regression models were used to estimate the hazard ratio (HR) for GGT with incident NAFLD after adjusted demographic and clinical variables. (HR, 1.010; 95% CI, 1.007–1.012; P < 0.001). The incident NAFLD in the highest quartile of GGT levels was 3.653 times as high (95% confidence interval, 2.915 to 4.579) as that in the lowest quartile. A non-linear relationship was firstly detected between GGT and incidence of NAFLD, which had an inflection point of GGT was 26U/L. The effect sizes and the confidence intervals on the left and right sides of the inflection point were 1.104(1.089–1.120)and 1.001༈0.999–1.004༉, respectively. In subgroup analyses, the hazard ratio for incident NAFLD remained consistent across subgroups.
Conclusion

In conclusion, the GGT level in the non-obese Chinese population was statistically significantly associated with incident NAFLD. The relationship between GGT level and incident NAFLD is non-linear. When GGT level is less than 26 U/L, GGT was strong positively with incident NAFLD.
Defining the Sensitivity Landscape of 74,389 EGFR Variants to Tyrosine Kinase Inhibitors
Authors: An Lei , Chen Shuqing , Wu Guangyao , Liu Chang , Wang Zhenxing , Wang Chunli , Shi Zeyuan , Niu Chenguang , Li Xiaodong , Tang Wenxue , Xu Hongen , Wang Yueqiang
Published: September 2021

Background: Tyrosine kinase inhibitors (TKIs) therapy is a standard treatment for patients with advanced non-small-cell lung carcinoma (NSCLC) when activating epidermal growth factor receptor (EGFR) mutations are detected. However, except for the well-studied EGFR mutations, most EGFR mutations lack treatment regimens. Methods: We constructed two EGFR variant libraries containing substitutions, deletions, or insertions using the saturation mutagenesis method. All the variants were located in the EGFR mutation hotspot (exons 18–21). The sensitivity of these variants to afatinib, erlotinib, gefitinib, icotinib, and osimertinib was systematically studied by determining their enrichment in massively parallel cytotoxicity assays using an endogenous EGFR-depleted cell line, PC9.Results: A total of 3,914 and 70,475 variants were detected in the constructed EGFR Substitution-Deletion (Sub-Del) and exon 20 Insertion (Ins) libraries, accounting for 99.3% and 55.8% of the designed variants, respectively. Of the 3,914 Sub-Del variants, 813 were highly enriched in the reversible TKI (erlotinib, gefitinib, icotinib) cytotoxicity assays and 51 were enriched in the irreversible TKI (afatinib, osimertinib) cytotoxicity assays. For the 70,475 Ins variants, insertions at amino acid positions 770–774 were highly enriched in all the five TKI cytotoxicity assays. Moreover, the top 5% of the enriched insertion variants included a glycine or serine insertion at high frequency. Conclusions: We present a comprehensive reference for the sensitivity of EGFR variants to five commonly used TKIs. The approach used here should be applicable to other genes and targeted drugs.
Fired Heater Simulation, Modelling and Optimization
Authors: brakat Taj Alasfia M , Hassan Mahmoud Adam
Published: September 2021

In this study a dynamic model Simulation was carried out using ASPEN HYSY for industrial refinery fired heater, PID controller was applied to control the flue gas exit temperature. the simulation shows perfect agreement with the datasheet of the furnace. It was found that Increasing the number of the tube rows in convection bank from 2 to 3 allows us to recover approximately 5% of the overall efficiency, hence the duty furnace has increased from 65.9MW to 68.1MW and the fuel flow in like manner has increased from 5597kg/h to 5807kg/h moreover Adding more rows has a reverse return as we start to notice increase on the flue gas temperature. Furthermore, sensitivity analysis was conducted with HYSYS to determine one of the most important parameters that affect the performance of the heater based on the data generated from the simulation. MATLAB code was generated for efficiency calculation and for parameter manipulation, the code was designed to be flexible as possible, user will just need to replace the nominal fuel and air characteristics. for gaining optimum furnace operation the heat transfer inside the furnace was studied, and the results were compared with previous research involving furnace analysis to validate models, the heat transfer coefficient is determined by analysis of conductive heat transfer through the boundary layer. well-stirred model was used for mathematical model calculations and for optimization of furnace operation, the models were validated with ASPEN Exchanger Design and Rating(EDR) alongside ASPEN HYSYS
Comparative Transcriptome Analysis of Storage Root Reveals Regulatory Mechanisms of Lignin Biosynthesis During Root Development in Two Sweetpotato Cultivars
Authors: Hou Fuyun , Qin Zhen , Du Taifeng , Zhou Yuanyuan , Li Aixian , Dong Shunxu , Ma Daifu , Zhang Liming , Li Zongyun , Wang Qingmei
Published: September 2021

BackgroundSweetpotato(Ipomoea batatas (L.) Lam.) is one of the most important crops with high storage roots yield. Lignin affects the storage root formation. However, the molecular mechanisms of lignin biosynthesis in storage roots development have been lacking.ResultsTo reveal the molecular mechanism of lignin biosynthesis and identify new homologous genes in lignin biosynthesis during storage root development, the storage root (SR) at three different stages (D1, D2 and D3) in the two cultivars (Jishu25 and Jishu29) was investigated with full-length and second-generation transcriptome. A total of 52,137 transcripts and 21,148 unigenes were obtained after corrected with Hiseq2500 sequencing. Through the comparative analysis, 9577 unigenes were found to be differently expressed in the different stage in two cultivars. Among of them, 91 unigenes enriched in the phenylpropanoid biosynthesis, and 201 unigenes in hormone signal transduction pathway with KEGG analysis. Weighted gene co-expression network analysis of differentially expressed unigenes showed that lignin biosynthesis genes might be co-expressed with transcription factors such as AP2/ERF and MYB at the transcription level, and regulated by phytohormones auxin and GA3.Conclusions﻿Taken together, our findings will throw light on molecular regulatory mechanism of lignin biosynthesis involved in storage root development.
Induction of Internal Circadian Desynchrony by Misaligning Zeitgebers
Authors: Heyde Isabel , Oster Henrik
Published: September 2021

24-hour rhythms in physiology and behaviour are orchestrated by an endogenous circadian clock system. In mammals, these clocks are hierarchically organized with a master pacemaker residing in the hypothalamic suprachiasmatic nucleus (SCN). External time signal – so-called zeitgebers – align internal with geophysical time. During shift work, zeitgeber input conflicting with internal time induces circadian desynchrony which, in turn, promotes metabolic and psychiatric disorders. However, little is known about how internal desynchrony is expressed at the molecular level under chronodisruptive environmental conditions. We here investigated the effects of zeitgeber misalignment on circadian molecular organisation by combining 28-hour light-dark (LD-28) cycles with either 24-hour (FF-24) or 28-hour feeding-fasting (FF-28) regimes in mice. We found that FF cycles showed strong effects on peripheral clocks, while having little effect on centrally coordinated activity rhythms. Systemic, i.e., across-tissue internal circadian desynchrony was induced within four days in LD-28/FF-24, while phase coherence between tissue clocks was largely maintained under LD-28/FF-28 conditions. In contrast, temporal coordination of clock gene activity across tissues was reduced under LD-28/FF-28 conditions compared to LD-28/FF-24. These results indicate that timed food intake may improve internal synchrony under disruptive zeitgeber conditions but may, at the same time, weaken clock function at the tissue level.
Structural, Magnetic Properties and Hyperthermia Efficiency of MF/CuAl2O4 Multiferroic Nanocomposite
Authors: Roumaih Roumaih , Abd-elrahem Ismail , Hussein Shaban I.
Published: September 2021

The multiferroic MF/CuAl2O4 (MF= CoFe2O4, NiFe2O4, MgFe2O4, and ZnFe2O4) was prepared using two stages of the sol-gel method. X-ray Diffraction (XRD), the Fourier transforms infrared absorption (FT-IR) and High-resolution Transmission Electron Microscope (HR-TEM) were used to examine the structure of all samples. From the XRD patterns, two standards of cubic spinels structure (CuAl2O4 + MF) were observed. The analysis of FTIR spectra confirmed the formation of the chemical and molecular structure changes in the MF/CuAl2O4. HR-TEM images showed a uniform particle distribution with a nanoscale of all samples. The magnetic properties were studied from the hysteresis loops using a vibrating sample magnetometer (VSM) and the magnetization M (T) by the Faraday balance method. All samples exhibited typical ferrimagnetic behavior, except for ZnF/CuAl recorded superparamagnetic. Curie temperature (TC) for all nanocomposites obtained from M(T) protocols, which is lower than the standard value of MF nanoferrites. The heating efficiency of all samples was investigated by measuring the Specific Absorption Rate (SAR) parameter. The SAR of NiF/CuAl showed a maximum value as well as saturation magnetization (Ms) and lowest coercivity (Hc) value.
Viridibacillus Soli sp.nov., Isolated from Forest Soil in Ailaoshan National Nature ReserveViridibacillus Soli sp.nov., Isolated from Forest soil in Ailaoshan National Nature Reserve
Authors: Xu Yan , Zhao Jiang-Yuan , Geng Yu , Yuan Hui-Ren , Li Le-Le , Wen Meng-Liang , Li Ming-Gang , Tang Shu-Kun
Published: September 2021

A Gram-staining positive, rod-shaped, and subterminal endospore-forming bacterium, designated strain YIM B01967T, was isolated from a forest soil sample collected in Ailaoshan National Nature Reserve, Yuxi City, Xinpin county, Yunnan province, China. Strain YIM B01967T showed the highest 16S rRNA gene sequence similarity with Viridibacillus arvi (99.1%) and Viridibacillus arenosi (98.9%). Based on the phylogenetic and 16S rRNA gene sequence results, strain YIM B01967T was affiliated to the genus Viridibacillus. The growth of YIM B01967T was observed at 15–35°C (optimum, 28°C), pH 7.0–9.0 (optimum, pH 7.5) and in the presence of 0–2% (w/v) NaCl (optimum in 2% NaCl). The cell-wall sugars include ribose, glucose, arabinose, galactose, and mannose. The quinone system consisted of the major compound MK-8 and moderate amounts of MK-7. The major fatty acids (> 10%) were iso-C15:0, anteiso-C15:0, C16:1 ω10c. The major polar lipids profile included DPG, PME. The cell wall peptidoglycan was most likely of the type A4α with an L-Lys–D-Asp interpeptide bridge. The genomic DNA G + C content of strain YIM B01967T was 36.3 mol%. The ANI and dDDH values between strain YIM B01967T and the two reference strains Viridibacillus arvi DSM 16317T and Viridibacillus arenosi DSM 16319T are 61.0% and 32.1%, 60.0% and 33.1% based on the draft genome sequence. The results support the conclusion that strain YIM B01967T represents a novel species of the genus Viridibacillus, the for which the name Viridibacillus soli sp. Nov., is proposed.The type strain is YIM B01967T (= KCTC 43249T = CGMCC 1.18436T).
Efficient Electromagnetic Transducers For Spin-Wave Devices
Authors: Connelly David , Csaba Gyorgy , Aquino Hadrian Renaldo O. , Bernstein Gary H. , Orlov Alexei , Porod Wolfgang , Chisum Jonathan
Published: September 2021

This paper presents a system-level efficiency analysis, a rapid design methodology, and a numerical demonstration of efficient sub-micron, spin-wave transducers in a microwave system. Applications such as Boolean spintronics, analog spin-wave-computing, and magnetic microwave circuits are expected to benefit from this analysis and design approach. These applications have the potential to provide a low-power, magnetic paradigm alternative to modern electronic systems, but they have been stymied by a limited understanding of the microwave, system-level design for spin-wave circuits. This paper proposes an end-to-end microwave/spin-wave system model that permits the use of classical microwave network analysis and matching theory towards analyzing and designing efficient transduction systems. This paper further compares magnetostatic-wave transducer theory to electromagnetic simulations and finds close agreement, indicating that the theory, despite simplifying assumptions, is useful for rapid yet accurate transducer design. It further suggests that the theory, when modified to include the exchange interaction, will also be useful to rapidly and accurately design transducers launching magnons at exchange wavelengths. Comparisons are made between microstrip and co-planar waveguide lines, which are expedient, narrowband, and low-efficiency transducers, and grating and meander lines that are capable of high-efficiency and wideband performance. The paper concludes that efficient microwave-to-spin-wave transducers are possible and presents a meander transducer design on YIG capable of launching λ=500nm spin waves with an efficiency of -4.45 dB and a 3 dB-bandwidth of 134 MHz.
Identification and Mitigation of High-Risk Pregnancy with the Community Maternal Danger Score Mobile Application in Gboko, Nigeria
Authors: Bola Rajan , Ujoh Fanan , Lett Ronald
Published: August 2021

Introduction Nigeria constitutes 1% of the world’s population yet accounts for 10% of global maternal mortality. Risk analyses within rural regions of Nigeria are not routinely conducted, yet could help inform access to skilled birth care. The objectives of this study were to assess the proportion of women at risk for mortality or morbidity in Benue State, Nigeria by analysing data collected during routine antenatal visits and through the Community Maternal Danger Score (CMDS), a validated risk-analysis tool. Methods Two cohorts, comprised of pregnant women presenting to primary healthcare centres within Gboko, Benue State between 2015-2017 and 2020-2021, were included in this study. The 2015-2017 cohort had their risk assessed retrospectively through analysis of routinely collected data. Identification of risk was based on their age, parity, and disease status (HIV and diabetes). The 2020-2021 cohort had their risk assessed prospectively using the CMDS. Results Routinely collected data from 2015-2017 demonstrated that up to 14.9% of women in Gboko were at risk for mortality or morbidity. The CMDS reported that up to 21.5% of women were at a similar level of risk; a significant difference of 6.6% (p=0.006). The CMDS was more efficient in obtaining and assessing this data, and the identification was available in real-time for midwives and pregnant women. Conclusion Routine data collected in Gboko identifies a high proportion of pregnant women at risk for mortality or morbidity. The CMDS is an evidence-based risk analysis tool that expands on this assessment by also estimating individual and community-level risk, which allows for more efficient mitigation and prevention strategies of maternal mortality.
Multiband Slotted Planar Inverted-F Antenna using Reactive Impedence Surface for Wireless Applicatios
Authors: Jadhav Tejaswi Mahaling J
Published: August 2021

This research work presents a low profile slotted planar invertedF antenna (PIFA) on a reactive impedance surface (RIS) for multiband. The quad-band frequency antenna for 2.4 GHz (WLAN), 4.2 GHz (C-band satellite downlink), 7.1 GHz (C-band satellite uplink), and 9 GHz (X-band )for wireless applications. The structure of the proposed PIFA has a compacted patch size of 23.33 mm × 2.66 mm × 1 mm placed on a dielectric substrate flame retardant 4(FR4) material, along with tangent loss = 0.02. The proposed antenna used two dielectric substrates whose heights are h1 = 1.59 mm and h2 = 1 mm . The rectangular slot is added in a radiating patch of the PIFA for multiband operations. The proposed antenna improves the parameters such as reduction scale, efficiency, narrow bandwidth, and gain enhancement. The slotted PIFA shows a quad-band with an S11 <-10 dB bandwidth of approximately 15.83% (2.24-2.62 GHz), 11.19% (3.93-4.4GHz), 12.67% (6.90-7.80GHz) and 10.55% (8.29-9.24GHz) under measurement. The proposed antenna design is excited by 50Ω microstrip line feed. The antenna exhibits radiation pattern, gain, and impedance matching across their operating bandwidths to demonstrate the benefits of multiple PIFA.
Optical Theodolite Based Rationality Check of Measurement Data From Pulse Radar
Authors: Hu Shaolin , Jiang Wenqiaqng , Liang Jiahui , Li Jian
Published: September 2021

Theodolite and radar are important measurement and control devices in aviation, aerospace and other fields. In order to make sure the tracking measurement and navigation control of aircraft and spacecraft safely, this paper creatively proposes a novel method to check the rationality of the three-dimensional measurement data (distance, azimuth and pitch angle) of the pulse radar by using the two-dimensional measurement data (azimuth and pitch angle) of the optical theodolite. Specifically, three different rationality checking functions are constructed for the three different cases of unreliable ranging channel, unreliable angle measuring channel and unreliable ranging and angle measuring channels, and are used for the rationality checking of radar data in the above three cases respectively. Simulation results show that the correct rate is more than 95% as long as the data measured by optical theodolite are reliable.
Corona - eine Krise für die Kooperation?
Authors: Langner Anke , Milker Clemens
Published: September 2021

Der Artikel greift vor dem Hintergrund der Theorieperspektive der Synthetischen Humanwissenschaften auf, wie sich Kooperationsbeziehungen von Schüler*innen und Lehrpersonen in ihrer Intensität wie Funktionalität durch die pandemiebedingt plötzlich und signifikant auftretenden Änderungen des Alltags der Institution Schule verändern. Dies wird hinsichtlich der Auswirkungen auf individuelle Entwicklung und Entwicklungspotentiale von Schüler*innen gespiegelt, um daran anknüpfend Ableitungen für Bildungsprozesse zu ziehen. Einzelne Ausschnitte aus explorativ geführten Interviews erweitern den theoretischen Bezugsrahmen durch Aussagen von Praktiker*innen hinsichtlich einer schulischen und professionstheoretischen Perspektive.
 
Abstract
The article discuses theoretically how cooperation among students and teachers changed in its intensity and functionality for learning during the significant changes of the institution school due to the Corona-pandemic restrictions. Those changes are to be analysed in their influence on individual development and potentials. Selected explorative interviews with teachers and parents about their perception on the crisis and its caused changes may add a practical perspective from school to the pedagogical theory.
Applicability of photoelectrical solar units inside domical structures in northern conditions
Authors: Mestnikov N. P. , Vasilyev P. F. , Davydov G. I. , Khoyutanov A. M. , Alzakkar A. M.-N.
Published: September 2021

The possibility of installing photoelectrical solar units inside domical structures with the maintenance of their power generation level was investigated; an optimal distance between a photoelectrical solar unit and the transparent walls of the respective domical structure was determined. The experiments were carried out at the North-Eastern Federal University in the central part of the Republic of Sakha (Yakutia) by determining reduction in the electrical energy efficiency of photoelectrical solar units when changing their location. An optimal distance for installing such units within transparent domical structures was found based on graphical interpretations and gradients. The authors obtained reference parameters for light flux reduction, the generation power of a photoelectrical solar unit when changing the operation medium, and the optimal distance of a photoelectrical solar unit inside a domical structure for reducing the surface contamination of the unit. It was found that, when photoelectrical solar units are operated within a transparent domical structure, the power generation falls by 25.61% as compared to actual results in open space. It was found that an increase in the distance between the transparent walls of the domical structure and the unit led to a decrease in the power generation by ~23.01% and the light flux power by 5.224% at 1.5 m. This method of installing photoelectrical solar units can be used in the construction and designing of smart home systems and autonomous power generation facilities in northern regions of Russia.
Validation and optimization of a new instrument for measuring the performances of ultrafiltration membranes
Authors: Guo Linyuan , Rong Yan , Dai Qiang , Li Jingmiao , Feng Shichun , Jin Dong
Published: September 2021

In this study, we introduce the current situation of the membrane inspection industry. We have developed a new integrated rapid membrane inspection machine (MIM) to test the performances of nanofiltration or ultrafiltration membranes by measuring the silt density index (SDI) value (i.e., the key performance indicator) of the water filtered. This study optimizes many key conditions include temperature, pH value and pressures, then establishes a new SDI detection method of ultrafiltration membranes by using MIM. We set the temperature of the test liquid to 25 °C, pH in the range of 7–8, and pressure to approximately 0.10 MPa. The results reflect that MIM can be used to effectively determine the SDI of ultrafiltration membranes using the new method and the results of the method validation are satisfactory.
Świętożyzna – presumed wife of Świętopełk I
Authors: Latoszek Paweł
Published: August 2021

One of the most secretive persons in early medieval Slavia is Świętożyzna. Because her name appears in the Gospel Book of Cividale beside the name of the Moravian prince, she is considered to be his wife. She is also identified with anonymous bohemian princes, whose wedding conduct was attacked by Franks in 872. The Author of this paper tries to connect references of Świętożyzna and find approximate place of her origin including political contacts between Great Moravia and Bohemia in the second half of IXth century.
The operation of the Cardinal Stefan Wyszyński University (Warsaw) archive based on its reports from 2003 to 2015
Authors: Poletyło Roman
Published: August 2021

The 15th anniversary of the establishment of the Cardinal Stefan Wyszyński University (UKSW) archive is a good moment to reflect on its operation. Its annual reports enable us to recognize the scale and quality of the archive’s operation. Reports prepared between 2003 and 2015 for various purposes and authorities show how the archive has fulfilled its basic duties.

The quality of UKSW’s archive is monitored by the State Archive in Warsaw.As ainter-faculty unit of UKSW, the archive also comes under the authority of one of the University’s deputy vice-chancellors.The archive mainly reports to these principal bodies on an annual basis.The archive holds the records of the Warsaw Theological Academy which was later transformed into UKSW.
Marriage ceremonies in medieval Poland
Authors: Wojciechowska Beata
Published: August 2021

Marriage was an important milestone in the lives of two people who decided to establish a family and enter into new family and neighborhood arrangements. In the Middle Ages, wedding ceremonies in Poland took on a time-honored ritual form, in which local traditions merged with the more recent Christian influences. Matrimony was recognized as a sacrament which symbolically emphasized the importance of events and was promised to provide future happiness for the newlyweds. The wedding ceremony was preceded by three public announcements in church. It was stipulated that the ceremony be held in church, in the presence of witnesses. Its main elements included the spousal handshake, the exchange of gifts in the form of wreaths, wedding rings or other gifts, and the utterance of the wedding formula: I take thee as my husband/wife.
Cidadania e Deficiência
Authors: Baia Marcelo Santos
Published: August 2021

A história da deficiência no mundo passa por episódios de discriminação e pela busca deste grupo pelos mesmos direitos que as outras pessoas que não possuem qualquer deficiência ou dificuldade. Por meio de vários diplomas legais específicos de seus países, como a constituição e de tratados entre países, como a Convenção sobre os Direitos das Pessoas com Deficiência, os deficientes foram sendo amparados legalmente, chegando ao ponto da discriminação contra um deficiente ser considerado crime. Contudo, além da questão da discriminação, os deficientes acabam não tendo seus direitos constitucionais respeitados devido à falta de acessibilidade, de acesso à Educação e conseqüentemente a uma vida mais digna. Este artigo tem por objetivo geral apresentar a relação existente entre a cidadania e deficiência. Para isso ambos os termos serão não apenas conceituados, mas apresentadas estatísticas referentes á deficiência em Portugal. Por fim será discutido como a cidadania é o meio de inclusão dos deficientes em Portugal. Para alcançar tais objetivos utilizou-se como metodologia científica a revisão de literatura de artigos científicos, dissertações, livros, além de documentos oficiais relacionados ao tema, ou seja, a deficiência e a cidadania.
TDAH em adultos e suas implicações em âmbito acadêmico
Authors: Silva Michely Aparecida , Laport Tamires
Published: August 2021

O Transtorno de Déficit de Atenção e Hiperatividade (TDAH) é um transtorno do neurodesenvolvimento que surge normalmente na infância, se estendendo até a vida adulta, podendo afetar questões de origem socioafetiva, acadêmica e profissional, além de ser um dos principais focos de estudo atualmente, tanto na área da saúde como da educação. Diante disso, o objetivo deste trabalho é discutir sobre a atuação do docente em âmbito acadêmico diante de alunos que apresentem características peculiares ao TDAH. O que se busca aqui é analisar a invisibilidade marcante na educação referente ao TDAH de jovens e adultos. Já que, atualmente, situações de alunos com dificuldades de aprendizagem e baixo rendimento acadêmico têm sido identificados com maior frequência. Além disso, o diagnóstico do TDAH é mais recorrente na infância, o que faz com que seu reconhecimento entre jovens e adultos não seja muito discutido. Trata-se, portanto, de uma revisão bibliográfica, tendo como fontes: artigos científicos, livros, trabalhos acadêmicos e periódicos on-line, com o intuito de investigar propostas de diferentes autores e com aproximação ao tema abordado, para a complementação de ideias e concepções.
Withdrawal Notice: Colchicine May Induce Isolated and Reversible Oculomotor
Neuropathy
Authors: Gorgone Gaetano , Plastino Massimiliano , Vaccaro Antonio , Fava Antonietta , Bosco Domenico
Published: September 2021

The article has been withdrawn at the request of the editor of the journal Current Reviews in Clinical and Experimental Pharmacology
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THE EFFECT OF GLUT4 EXPRESSION IN HIPPOCAMPAL NEURONS TO SPATIAL MEMORY OF DIABETES-INDUCED RATTUS NOVERGICUS
Authors: Syafii Harahap Herpan , Padauleng Novrita , Vidya Lestari Rizka , Nurhidayati Nurhidayati , Agung Ayu Niti Wedayani Anak , Suwita Sari Putu , Haq Muliyana Hifdzil , Putu Proudy Laksmana Ngakan , Raudatin Sahly Aliza
Published: August 2021

Background: Identification of appropriate biomarker involved in the pathophysiology of diabetes-associated cognitive decline in animal model is necessary. Glucose transporter 4 (GLUT4) is the component of insulin-dependent neuronal signaling pathway needed for maintaining cognitive function. It is highly expressed in hippocampal neurons. Objective: To investigate the effect of GLUT4 expression in hippocampal neurons on the spatial memory of diabetes-induced Rattus novergicus. Methods: This experimental study used 24 male Rattus novergicus divided into control groups terminated on day-0 (C0), 14 (C1) and 28 (C2) and diabetic groups terminated on day-0 (D0), 14 (D1) and 28 (D2). Diabetes was induced using streptozotocin injections intraperitoneally. Spatial memory (travel time) of rats was assessed on day-14 and 28. Brain tissue sampling was performed for assessment of GLUT4 expression using immunohistochemical methods. Significant differences in means of GLUT4 expression and travel time between groups on day-0, 14 and 28 as well as correlation between means of GLUT4 expression and travel time in D1 and D2 were analyzed statistically. Results: The mean of GLUT4 expression in diabetic group was significantly higher compared to control on day-14, but not on day-0 and 28. The immunohistochemical examination confirmed this results. There were no significant differences in mean of travel time between control and diabetic groups on day-14 and 28. There were no significant correlation between means of GLUT4 expression and travel time in diabetic groups on day-14 and 28. Conclusion: The GLUT4 expression of hippocampal neurons did not significantly affect spatial memory of diabetes-induced Rattus novergicus.
INDUSTRIAL REVOLUTION 4.0 IN NEUROREHABILITATION: THE IMPLEMENTATION OF VIRTUAL REALITY FOR NEUROLOGICAL DISORDERS
Authors: Eka Widyadharma I Putu , Prathama Limalvin Nicholas , Pramana Dharmatika I Made , G Gayathridayawasi , Ayu Sri Indrayani Ida , Nugraha Boya
Published: August 2021

Industrial revolution 4.0 has changed the health industry. Medical treatments derived from the latest technologies are expected to improve health and economic status. The rapid development of technology has influenced the learning and clinical practice of medicine. Virtual Reality (VR) is one of the latest technologies that is currently being implemented as a treatment for neurological disorders. This article seeks to give an overview of the development of VR implementation in neurorehabilitation. The data source of this article is research and studies published in NCBI, PubMed, Cochrane, and other relevant online databases. From this article, it is found that VR can be used as a pain reliever and motor function rehabilitation for patients with balance and gait deficits. VR is used to distract patients’ attention to pain for a short time period. VR also improves motor function recovery in stroke patients. Cybersickness is usually reported as a side effect of using VR and it depends on each individual. The implementation of VR for patients with neurological disorders has showed advantages in reducing pain and improving motor function but still need further research about applicability and authorization of virtual reality in the world of medicine.
Pandemics 2020 –COVID 19 Silent Hypoxia and Polysubstance Use: A Unique Case Report
Authors:   Naval Medical Center Portsmouth, Portsmouth, Virginia, Owens Michael D. , Halliday Megan ,   Naval Medical Center Portsmouth, Portsmouth, Virginia
Published: September 2021

The coronavirus (COVID-19) pandemic continues to bring challenges in identification and management of which the “happy hypoxic” or silent hypoxia presentation has been found to present its own unique challenge. A 67-year-old African American COVID-19 positive female presents to the emergency department (ED) with a chief complaint of decreased oral intake and responsiveness, oriented and stable, with oxygen saturations found to drop as low as 47%. The patient was successfully managed with supplemental oxygen and determined to be a “happy hypoxic” with recent polysubstance abuse. Silent hypoxia or the “happy hypoxic” patient is another unique phenomenon associated with the variable presentations of COVID-19. Multiple etiologies and pathophysiologic explanations exist to explain this stable patient whom would otherwise be expected to require aggressive management with a poor prognosis. An alternative diagnosis should be explored for those silent hypoxic patients with symptoms.
Comparative analysis of the physicochemical composition of pea cultivars
Authors: Guindon María Fernanda , Aguero María Gabriela , Gatti Ileana , Cointry Enrique
Published: September 2021

Peas are an inexpensive nutrient source. Basic information about variation in physicochemical composition is required to manage breeding programs and postharvest operations effectively. Different properties were measured in seeds from 16 promising pea genotypes to study variability between lines, degree of genetic parameters, and associations among different traits. Seed weight and diameter, pH, and titratable acidity showed the highest values for broad-sense heritability and the most negligible differences between the phenotypic and genetic coefficient of variation, indicating that these traits’ variability was predominately due to genotypic differences. Genotypes had a wide-range profile that could be related to morphological and physiological properties. Yellow varieties showed superior values for weight and sizes (27.84 g; 0.57 cm) and small changes in diameter after hydration (48.35 %), while wrinkled varieties showed inferior moisture content (9.54 %), higher hydration capacity (1,314.66 g H2O/kg seeds), and protein content (28.88 %). Cuarentina and B315 were the more resistant and firmer materials; B315 also had the highest water hydration capacity, which would be appropriate for canning. Polyacrylamide gels demonstrated differences in protein composition; Gypsi contained more legumin (47.27 %) than the other genotypes, which is more beneficial nutritionally, and contained less convicilin (7.06 %), making it suitable for the food industry. Using accelerated aging, we studied color changes due to storage and established that the Viper line was highly tolerant to it. We could identify lines that may be exploited by industry or quality breeding programs.
The Effect of Telehealth on Hospital Services Use: Systematic Review and Meta-analysis
Authors: Peters Guido M , Kooij Laura , Lenferink Anke , van Harten Wim H , Doggen Carine J M
Published: September 2021

Background

Telehealth interventions, that is, health care provided over a distance using information and communication technology, are suggested as a solution to rising health care costs by reducing hospital service use. However, the extent to which this is possible is unclear.

Objective

The aim of this study is to evaluate the effect of telehealth on the use of hospital services, that is, (duration of) hospitalizations, and to compare the effects between telehealth types and health conditions.

Methods

We searched PubMed, Scopus, and the Cochrane Library from inception until April 2019. Peer-reviewed randomized controlled trials (RCTs) reporting the effect of telehealth interventions on hospital service use compared with usual care were included. Risk of bias was assessed using the Cochrane Risk of Bias 2 tool and quality of evidence according to the Grading of Recommendations Assessment, Development and Evaluation guidelines.

Results

We included 127 RCTs in the meta-analysis. Of these RCTs, 82.7% (105/127) had a low risk of bias or some concerns overall. High-quality evidence shows that telehealth reduces the risk of all-cause or condition-related hospitalization by 18 (95% CI 0-30) and 37 (95% CI 20-60) per 1000 patients, respectively. We found high-quality evidence that telehealth leads to reductions in the mean all-cause and condition-related hospitalizations, with 50 and 110 fewer hospitalizations per 1000 patients, respectively. Overall, the all-cause hospital days decreased by 1.07 (95% CI −1.76 to −0.39) days per patient. For hospitalized patients, the mean hospital stay for condition-related hospitalizations decreased by 0.89 (95% CI −1.42 to −0.36) days. The effects were similar between telehealth types and health conditions. A trend was observed for studies with longer follow-up periods yielding larger effects.

Conclusions

Small to moderate reductions in hospital service use can be achieved using telehealth. It should be noted that, despite the large number of included studies, uncertainties around the magnitude of effects remain, and not all effects are statistically significant.
US Physicians’ and Nurses’ Motivations, Barriers, and Recommendations for Correcting Health Misinformation on Social Media: Qualitative Interview Study
Authors: Bautista John Robert , Zhang Yan , Gwizdka Jacek
Published: September 2021

Background

Health misinformation is a public health concern. Various stakeholders have called on health care professionals, such as nurses and physicians, to be more proactive in correcting health misinformation on social media.

Objective

This study aims to identify US physicians’ and nurses’ motivations for correcting health misinformation on social media, the barriers they face in doing so, and their recommendations for overcoming such barriers.

Methods

In-depth interviews were conducted with 30 participants, which comprised 15 (50%) registered nurses and 15 (50%) physicians. Qualitative data were analyzed by using thematic analysis.

Results

Participants were personally (eg, personal choice) and professionally (eg, to fulfill the responsibility of a health care professional) motivated to correct health misinformation on social media. However, they also faced intrapersonal (eg, a lack of positive outcomes and time), interpersonal (eg, harassment and bullying), and institutional (eg, a lack of institutional support and social media training) barriers to correcting health misinformation on social media. To overcome these barriers, participants recommended that health care professionals should receive misinformation and social media training, including building their social media presence.

Conclusions

US physicians and nurses are willing to correct health misinformation on social media despite several barriers. Nonetheless, this study provides recommendations that can be used to overcome such barriers. Overall, the findings can be used by health authorities and organizations to guide policies and activities aimed at encouraging more health care professionals to be present on social media to counteract health misinformation.