bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of polarity-reversed endometrial epithelial organoids
Authors: Ahmad Vakil , Yeddula Sai Goutham Reddy , Telugu Bhanu P , Spencer Thomas E , Kelleher Andrew M
Published: January 2024

In brief

Polarity-reversed endometrial epithelial organoids exhibit histological and physiological characteristics resembling uterine epithelium in vivo, respond to hormones, and undergo secretory cell transformation. The ability to modify the polarity without impairing functionality, coupled with successful coculture with microbial and embryonic entities, paves the way for investigating complex interactions at the endometrial epithelial surface.

The uterine epithelium comprises a single layer of hormone-responsive polarized epithelial cells that line the lumen and form tubular glands. Endometrial epithelial organoids (EEO) can be generated from uterine epithelia and recapitulate cell composition and hormone responses in vitro. As such, the development of EEO represents a significant advance in facilitating mechanistic studies in vitro. However, a major limitation of the use of EEO cultured in basement membrane extract and other hydrogels is the inner location of the apical membrane (apical-in EEO), thereby hindering direct access to the apical surface of the epithelium to study interactions with the embryo or infectious agents such as viruses and bacteria. To address this challenge, we developed a suspension culture method to reverse the polarity of EEO. The result is an apical-out organoid that preserves a distinct apical–basolateral orientation and remains responsive to ovarian steroid hormones. Apical-out EEO were positive for the gland marker, FOXA2, and exhibited appropriate hormonal regulation of steroid hormone receptor expression. Notably, progesterone treatment resulted in secretory transformation in apical-out EEO, including a decrease in microvilli and cilia, and an increase in secretory granules. Likewise, reflective of in vivo conditions, ENPP3, a P4-regulated gene, was localized apically in steroid hormone-treated organoids. Coculture experiments with apical out EEO demonstrate the model’s utility in studying uterine epithelium interactions with bacteria (E. coli) and blastocysts. The apical out EEO model lays the foundation for developing new in vitro functional assays, particularly regarding epithelial interactions with embryos during pregnancy or other luminal constituents in a pathological or diseased state.
Prediction of withdrawal resistance of self-tapping screws in softwood structural lumber
Authors: Lee In-Hwan , Kim Keonho
Published: January 2024

The withdrawal resistance of self-tapping screws (STS) in Korean structural softwood in the vertical fiber direction was examined. Four representative softwood species were selected based on their specific gravity. Three STS fastener diameters were used for an STS penetration depth of 50 mm. The withdrawal capacity tended to increase with the specific gravity of the specimens and as the diameter of the STS increased. Primarily, the difference in strength was maximized as the STS diameter increased from 8 to 10 mm. Predictive experimental equations were proposed based on the experimental values of the relationship between the specific gravity of the structural material and the withdrawal resistance according to the diameter of the STS. The values were compared with the predicted values calculated using fastener and screw prediction equations proposed by the National Design Specification for Wood Construction (NDS) and European Standards (EN). The results calculated using the NDS prediction equations yielded a peak difference of 43% compared with the experimental withdrawal capacity, whereas the EN prediction equations yielded a difference of 0.7 to 1.14 times the experimental values. The ratios between the withdrawal capacity predicted by the proposed prediction equations and the experimental withdrawal capacity were the most similar, ranging from 0.80 to 1.15.
How Wagner Landed in a Far Away Galaxy: Examining Film from a Musical Perspective
Authors: Camillone Elise
Published: January 2024

What does music add to drama, or more specifically, movies? Without music, movies today would not be the same. When it comes to creating a film, the soundtrack is arguably just as important as videography or acting. Exploring the roots that soundtracks have in opera and investigating Wagner’s leitmotif will help discover how it influenced modern-day movie scoring. Furthermore, a deeper understanding of filmmaking can be obtained by examining the role music has to play in modern movies. The soundtracks from the original Star Wars trilogy films can be used to demonstrate the application of these things by looking deeply into how each theme is formed and how each one shapes the characters it represents as well as the story that is portrayed in a film.
Frequency of BRAF V600E/E2/D and V600K/R/M mutations in patients with malignant melanoma unresectable stage III-IIIC–IV from May to August-2021 at Unigem in Medellin
Authors: Erika Pino , Claudia Benítez , Clara Aristizábal , Laura Orozco , Olga Rincón , María Jiménez , Beatriz Aristizábal
Published: January 2024

Background: Melanoma is the most aggressive skin cancer type and is responsible for 80% of deaths from this entity. It is considered one of the tumors with the highest mutational load, with approximately 50% of cases in codon 600 of the BRAF gene. Objective: To determine the frequency of BRAF V600E/E2/D and BRAF V600K/R/M mutations in patients with malignant melanoma unresectable stage III-IIIC – IV, during the period May-2018 and August-2021, at UNIGEM, in Medellín. Methodology: Observational, retrospective study, which included 154 paraffin-embedded biopsies from patients with stage III-IIIC-IV unresectable malignant melanoma. The evaluation of the BRAF V600E/E2/D and BRAF V600K/R/M mutations was carried out through real-time PCR using the Idylla platform. Results: 154 test results for the BRAF V600 mutation were reviewed, with a total of 60 (38.9%) mutated cases, of which 56 (93.3%) correspond to the V600E/E2/D change, predominantly in minors or equal to 63 years of age. Conclusion: We found that in the population analyzed with metastatic melanoma, 38.9% of the patients presented alterations in the BRAF gene, more frequently in men, in the V600 E/E2/D codon and in the age group≤63 years.
Interfacility Transfer Outcomes Among Children With Complex Chronic Conditions: Associations Between Patient-Level and Hospital-Level Factors and Transfer Outcomes
Authors: Uthappa Diya M. , Ellett Tressa L. , Nyarko Tichelle , Rikhi Aruna , Parente Victoria M. , Ming David Y. , White Michelle J.
Published: January 2024

OBJECTIVES

Determine patient- and referring hospital-level predictors of transfer outcomes among children with 1 or more complex chronic conditions (CCCs) transferred to a large academic medical center.

METHODS

We conducted a retrospective chart review of 2063 pediatric inpatient admissions from 2017 to 2019 with at least 1 CCC defined by International Classification of Diseases, Tenth Revision codes. Charts were excluded if patients were admitted via any route other than transfer from a referring hospital's emergency department or inpatient ward. Patient-level factors were race/ethnicity, payer, and area median income. Hospital-level factors included the clinician type initiating transfer and whether the referring-hospital had an inpatient pediatric ward. Transfer outcomes were rapid response within 24 hours of admission, Pediatric Early Warning Score at admission, and hours to arrival. Regression analyses adjusted for age were used to determine association between patient- and hospital-level predictors with transfer outcomes.

RESULTS

There were no significant associations between patient-level predictors and transfer outcomes. Hospital-level adjusted analyses indicated that transfers from hospitals without inpatient pediatrics wards had lower odds of ICU admission during hospitalization (odds ratio, 0.46; 95% confidence interval, 0.22–0.97) and shorter transfer times (β-coefficient, −2.54; 95% CI, −3.60 to −1.49) versus transfers from hospitals with inpatient pediatrics wards. There were no significant associations between clinician type and transfer outcomes.

CONCLUSIONS

For pediatric patients with CCCs, patient-level predictors were not associated with clinical outcomes. Transfers from hospitals without inpatient pediatric wards were less likely to require ICU admission and had shorter interfacility transfer times compared with those from hospitals with inpatient pediatrics wards.
Enhancing Pedagogy in Islamic Studies Methodology: A Focus on Hadith Instruction
Authors: Umam Hoerul , Khadijah Ifah
Published: January 2024

This study endeavors to investigate strategies for enhancing the pedagogy of Islamic Studies methodology, rendering it more efficacious and pertinent to contemporary requisites, with particular emphasis on advancing the effectiveness of instruction and the progression of hadith studies within the domain of Islamic higher education. The overarching objective is to establish a comprehensive framework governing the methodological approach to the instruction of hadith. The methodological framework adopted in this investigation is inherently descriptive and analytical in nature. Data acquisition was undertaken through the meticulous analysis of scholarly literature, encompassing documentary research, and direct observation of hadith instruction within the precincts of Islamic higher education institutions. A scrupulous evaluation of the construct of Islamic Studies Methodology in the context of hadith pedagogy has unearthed a plethora of inadequacies that necessitate immediate rectification. This study posits a compelling argument for the imperative of reform in the domain of hadith instruction within Islamic higher education. The required initiatives for the amelioration of hadith instruction encompass: (1) A concerted amplification of the focus on the scholarly study of hadith methodology, with a view to fostering an enduring culture of erudition; (2) Augmentation of accessibility to digital resources and traditional Islamic literature; (3) The empowerment of innovation and technology as pedagogical tools to engender a more immersive and captivating learning experience; (4) Advocacy for an interdisciplinary approach to hadith instruction, affording students the opportunity to scrutinize hadith from a multiplicity of disciplinary vantage points; (5) The facilitation of an environment that encourages open discourse and a profound comprehension of the contextual underpinnings of hadith; and (6) The inculcation of the imperative of integrating both normative and historical dimensions in the teaching of hadith, to ensure a more contextualized understanding. These initiatives are anticipated to contribute to the augmentation of the efficacy of hadith instruction within Islamic higher education, providing students with a deeper comprehension of the subject matter and preserving the relevance of hadith in the contemporary milieu.
The Social Lives of Veiled Women: Exploring Religious Identity and Modern Society's Reactions
Authors: Suhendi Hendi , Wahyudi Ira
Published: January 2024

The primary objective of this study is to investigate and gain a comprehensive understanding of the social experiences of women who wear the veil in their everyday lives. The study seeks to achieve two key objectives: first, to discern the motivations driving women to wear the veil, and second, to examine the social dynamics governing their utilization of the veil in daily life. Employing a qualitative method with a phenomenological approach, data collection was carried out through interviews and observations. The findings of this study shed light on the diverse motivations that drive veiled career women to wear the veil. These motivations are rooted in various causal factors, including experiences of disturbance, societal influences, concerns, and familial issues. The overarching objective for these women is to fortify their faith and safeguard themselves against undesirable behaviors. Moreover, the study reveals that the veil holds multiple meanings for career women who wear it, such as serving as reminders, protective elements, expressions of gratitude, symbols of communication, obligations, and even challenges. The dynamics of communication among women who wear the veil, as explored in this study, encompass interactions with their immediate environment, their social circles, and communication within the workplace. These interactions elicit a spectrum of responses and reactions, ranging from rejection and alienation to serving as role models and sources of inspiration for others considering the practice of wearing the veil. This research provides valuable insights into the complex interplay of motives, meanings, and social interactions surrounding the practice of veiling among career women
Islamic Scholarship in The Malay World: The Multifaceted Contributions of Ulama
Authors: Haqqi Abdurrahman Raden Aji , Yani Achmad , Binti Hj Ahim Hjh. Rasinah , Binti Hj Dollah Hjh Sri Rahayu Nurjanah , Binti Hj Yahya Hjh. Sarinah , Binti Abdul Rahman Mariam , Binti Hj Yahya Hjh Masuriyati , Binti Hj Timbang Artini
Published: January 2024

This study explores the extensive roles and contributions of Ulama (Islamic scholars) in the Malay Archipelago, with a focus on their impact in the fields of Islamic economics, sciences, and mathematics. The research aims to illuminate how Ulama have shaped various aspects of Islamic culture, education, and intellectual thought in the region. A comprehensive literature review was conducted, examining historical texts, manuscripts, and scholarly works related to the Ulama. The study employed qualitative analytical approaches to assess the contributions of Ulama in the Malay Archipelago. Findings indicate that Ulama significantly influenced Islamic economics by aligning economic practices with Sharia principles, emphasizing justice and ethical compliance. In scientific and mathematical fields, Ulama integrated complex mathematical concepts with Islamic teachings, contributing to the advancement of these disciplines. The educational impact of Ulama, particularly through the pondok system, promoted self-reliance and entrepreneurship, while their cultural synthesis effectively combined Islamic knowledge with local traditions. The Ulama’s roles extended beyond religious instruction, encompassing broader societal, economic, and intellectual domains. Their contributions not only facilitated the spread of Islam but also respected and preserved local customs. The study underscores the Ulama’s enduring influence in shaping the educational and intellectual landscape of the Malay Archipelago.
Wittgenstein's Challenge: The Impossibility of a Private Language
Authors: Pikri Zainal
Published: January 2024

The feasibility of a private language, a concept previously entertained by philosophers like Locke and Russell, is rigorously disputed by Wittgenstein in his later works. This article critically examines Wittgenstein’s standpoint on the notion of a private language, with a specific focus on its plausibility. It meticulously investigates the five arguments proffered by Wittgenstein against the concept of a private language and evaluates the counterarguments presented by his critics. These arguments encompass the future use argument, the interpretation argument, the stage-setting argument, the use argument, and the practice argument. Through a comprehensive analysis of these arguments, Wittgenstein substantiates the intrinsic unattainability of a private language. A privately defined word lacks the fundamental attributes of language, notably an established meaning, usability, prospective applicability, practical implications, interpretability, and a coherent framework governing the roles of its constituent elements. Ultimately, it is asserted that a private language cannot exist autonomously, separate from a public language.
Haber Okuryazarlığı Eğitimi Alan Öğrencilerin Haber Algısı
Authors: Şencan İpek , Soydal İrem
Published: January 2024

Günlük yaşamda önemli bir yer tutan haber; gündemle, çevrede gerçekleşen olaylarla, farklı gelişmelerle ilgili bilgilenmeye yardımcı ve hatta alınan kararlara etki edebilme potansiyeli olan bir bilgi türü şeklinde tanımlanabilir. Dijital ortamların kullanımının ve kullanıcı etkileşiminin artmasıyla, alışılagelmiş gazetecilik bakış açısıyla yapılan haber tanımı sınırlı kalabilmektedir. Bu durum, değişen medya ortamına ve bunun etkilerine odaklanan haber okuryazarlığı eğitiminde haberin nasıl tanımlanması gerektiği sorusunu gündeme getirmektedir. Bu noktada, haber kullanıcılarının haberi nasıl algıladıkları ve nasıl tanımladıklarını anlamaya çalışmak önemlidir. Bu çalışmada, bir grup lisans öğrencisinin eleştirel düşünmeyi temel alan haber okuryazarlığı eğitimi almadan önce ve aldıktan sonraki haber algılarının değerlendirilmesi amaçlanmıştır. Yarı deneysel araştırma tasarımı kullanılarak, eğitim öncesi ve sonrasında öğrencilere öz değerlendirme testleri ile ön ve son testler uygulanmıştır. Bu testlerle öğrencilerin, haber kavramını bilme bakımından kendilerini nasıl değerlendirdikleri, haberi farklı örnekler içerisinde ayırt edip edemedikleri ve nasıl tanımladıklarından yola çıkılarak haber algıları anlaşılmaya çalışılmıştır. Sonuçta, haber kavramını bilme yönünden öğrenciler kendilerini özellikle eğitim sonrasında daha yüksek puanlarla değerlendirmişlerdir. Farklı içeriklere yönelik örnekler arasında haberi ayırt etme bakımından da öğrencilerin genelde iyi bir performans sergiledikleri ancak eğitim sonrasında yarıdan fazlasının köşe yazısı türündeki örneği de haber olarak işaretledikleri belirlenmiştir. Ayrıca, öğrencilerin eğitim sonrasındaki tanımlarında, “doğru”, “güvenilir”, “kesin”, “5N1K kuralına uygun” gibi haber niteliklerine odaklanan ifadeler kullandıkları görülmüştür. Tüm bunlardan hareketle, haber kullanıcılarının bir içeriğe haber niteliği atfederken haber okuryazarlığının temelini oluşturan eleştirel düşünme becerilerini kullanmalarının önemli olduğu söylenebilir. Bu becerilerin bireylere kazandırılabilmesi, yaşam boyu öğrenme pratiklerine uyarlanmış, zamana yayılmış ve farklı seviyelere uygun bilgi, haber gibi okuryazarlık türleri ya da eleştirel düşünmeye yönelik olarak tasarlanacak eğitimlerle mümkün hale gelebilir.
Implementing the flipped classroom model in mathematics class teaching
Authors: Orlić Sonja , Marić Mia , Petojević Aleksandar
Published: January 2024

The aim with this research was to examine how the implementation of the flipped classroom model (FCM) impacted the quality and durability of 4th grade students’ knowledge in the field of measuring and measures when compared to traditional teaching (TT). The research was conducted in Serbia on a sample of 135 students, divided into 3 groups. The 3 groups were a control group (C) which was taught mathematics content using the TT model, an experimental group 1 (E1) which was taught using the FCM, while the students in experimental group 2 (E2) were taught using the FCM – the teacher also provided them with feedback regarding their work and made recommendations for their further development. The results show that the students from the E2 group surpassed those from the C and E1 groups regarding the quality and durability of their knowledge in the field of measuring and measures. There was a statistically significant difference in the knowledge of students in this field at the lower cognitive level among all the groups, while the statistically significant difference at the higher cognitive level was seen between the C and the E2 and between the E1 and the E2 groups.
The Cross-Culture Challenges in Marketing Relationship Creation . Understanding Chinese Guanxi, Renqing, Lian, Mianzi, Xinyong, and Xinren from the Direct Experiences of Polish Managers (Beyond Hofstede’s Approach)
Authors:   Institute of Organization and Management in Industry – ORGMASZ in Warsaw, Linka Jarosław
Published: January 2024

Close relationships with all members of the market environment are now widely accepted by academics and practitioners as an excellent way of creating a sustainable, competitive advantage. However, views on exactly which activities constitute the essence of market relationships may differ significantly in various cultural contexts. The purpose of this paper is to explore the impact of Chinese culture on market relationship creation, focusing on specific guanxi networks with closely related indigenous cultural aspects, such as renqing, lian, mianzi, xinren and xinyong, in order to reveal their implications for the functioning of foreign companies in China. An emic approach was predominantly implemented in this analysis, in addition to a polemic on the commonly used assessment methods of culture impact that is based on Western evaluation and bipolar culture dimensions. The information presented is based on research carried out on thirty-eight cases of Polish companies in China that used a semi-structured interview technique with individual managers directly responsible for operations in this market. It is reinforced with a broad literature overview and many years of the author’s direct observations. In addition, some practical recommendations and further research are suggested.
The Values Underlying Teachers’ and Employers’ Expectations
Authors:   Nicolaus Copernicus University in Toruń, Chomczyńska-Rubacha Mariola , Rubacha Krzysztof ,   Nicolaus Copernicus University in Toruń
Published: January 2024

The authors present a grounded theory concerning teachers’ expectations of students and employers’ expectations of graduates. The analysis is based on empirical research while the interpretation of the results is based on critical theory. Employers’ expectations turned out to be wide-ranging and impossible for candidates. Teachers’ expectations, however, reproduced that part of employers’ expectations that can be linked to conformity, devotion, and faithfulness. In light of the authors’ interpretation, education fails to perform an emancipatory function, i.e. it fails to equip students with the critical competence necessary for active involvement in civil society. The labor market, on the other hand, is a dominating force that blocks the development of a discursive, open version of society. Graduates find themselves in a double-sided trap sprung on them, firstly, by education and later by employers.
Health of Young People as One of the Elements of the State Youth Policy in Ukraine
Authors:   Lesya Ukrainka Eastern European National University, Naidych Maryna A.
Published: January 2024

The study is prepared at the Department of International Information of Lesya Ukrainka Eastern European National University. The paper describes the healthcare system in Ukraine. The basic legal documents that relate directly to this issue are considered. The main health threats for Ukrainian youth are defined. Some of the social programs and projects related to healthy lifestyle of Ukrainian youth are examined.
Towards the Welfare State Sociology
Authors:   Adam Mickiewicz University in Poznań, Baranowski Mariusz
Published: January 2024

The undeniable fact is that various social sciences and other disciplines constitute the research perspective which relates to the practice of a multidimensional phenomenon. The welfare state is an excellent example of such notion, which in its nature unifies many theoretical and practical positions. It seems, however, that the economic and political dimensions of the welfare state (as conceptual or pro-social proposals) are disproportionately exposed both on the basis of scientific reflection and pragmatic approaches used by the institutions of the state. This tendency to think in economic and political terms, which incidentally is maintained for several decades, represents: (a) only one side of a complex nature of social welfare, and (b) a significant reductionism, leading to the elimination of sociological, cultural, educational, and psychological consequences of the functioning of the welfare state. This article is designed to reverse the trend of the dominant perception of the construct of the welfare state in economic and political terms, and replace it with the highlight of the mainly sociological dimension of this phenomenon (the welfare state sociology). However, it does not mean abandonment of the economic and political dimensions in general, as they are an integral part of the issue.
Why Do We Expect More from Politics at a Time When It Is Supposedly Able to Do Less? Comparing Interwar Crisis Economics and Post-War Welfare Politics
Authors:   Södertörn University, Sweden, Marklund Carl
Published: January 2024

Looming crisis, public discontent with privatization, and widening inequalities are factors which have historically set the electorate in favour of social democratic welfare policies. Today, however, these concerns rather appear to support new right-wing populist countermovements, even in the traditionally progressive Nordic countries. This article asks why there is not more explicit support of progressive policies, despite the presence of socio-economic factors which would normally favour such a policy shift , at least not just yet. In response to this query, the article first analyses the comparisons between the present crisis and the crisis of the 1930s with regard to alleged political inertia. It then reinterprets the contemporary political consequences of crisis by revisiting three classical social theorists who took pains at analysing the political responses to the economic crisis of the 1930s: Karl Popper, Gunnar Myrdal, and Karl Polanyi. On the basis of this revisitation of these three classics, the article argues that the combined effects of distrust in politics and the persistence of admittedly rolled-back welfare systems mutes the progressive reform potential of the present crisis.
Autoritarismo e ortodoxia econômica: Chile 1974-87
Authors: GATICA JAIME , MIZALA ALEJANDRA
Published: January 2024

RESUMO O objetivo deste artigo é avaliar o modelo econômico chileno implementado durante o regime militar entre 1974-1987. Argumenta-se que as políticas ortodoxas postas em prática durante esses anos levaram a um crescimento lento e pioraram as condições de vida da maioria da população. As principais reformas e políticas de estabilização são apresentadas em primeiro lugar. Em segundo lugar, a partir de indicadores oficiais avaliamos os resultados dessas medidas comparando-os com o desempenho econômico chileno dos anos sessenta e com os de outros países da América Latina. Por fim, na conclusão, apresentamos brevemente as principais questões que envolvem uma estratégia econômica futura.
Subtipos de Dislexia do Desenvolvimento Descritos no Português Brasileiro: Uma Revisão Integrativa
Authors: Aurich Marina Musso , Peixoto Camila Batista , Amorim Luciano da Silva , Lopes-Silva Júlia Beatriz
Published: January 2024

Resumo A heterogeneidade na dislexia do desenvolvimento pode ser compreendida por meio dos subtipos de dislexia do desenvolvimento (SDD), porém não foram encontrados estudos que avaliassem a literatura brasileira sobre SDD. A presente revisão buscou responder quais SDD foram identificados no português brasileiro. Foram incluídos estudos empíricos, em inglês ou português, que descrevessem ao menos um SDD, bem como critérios diagnósticos, com participantes brasileiros. As buscas foram realizadas nas bases Scielo, Pubmed e Google Scholar. Como resultado, foram encontrados 11 estudos referentes a seis SDD, sendo as dislexias fonológicas e de superfície as mais presentes, e foram descritas as definições, critérios de identificação e instrumentos de avaliação utilizados em cada estudo. Foi discutida a heterogeneidade de definições, critérios de identificação e instrumentos de avaliação encontrados. Destacam-se o pequeno número de relatos em comparação com a literatura internacional e a necessidade de tarefas padronizadas, validadas e sensíveis aos SDD no português brasileiro.
Evidências de Validade da Escala RASH - Relação, Autonomia, Separação e Heteronomia em uma Amostra de Brasileiros e Norte Americanos
Authors: Palhares Fernanda , Freitas Lia Beatriz de Lucca , Tudge Jonathan Richard Henry
Published: January 2024

Resumo A Escala RASH (relação, autonomia, separação e heteronomia) foi desenvolvida para investigar padrões de self em estudos transculturais. No presente estudo, foi realizada uma análise fatorial da escala RASH em amostras brasileiras e norte-americanas, com o objetivo de fornecer uma medida de quatro fatores com bons índices de ajuste. Buscou-se confirmar o padrão de self autônomo-relacionado nas duas amostras e também a relação entre o nível de escolaridade dos pais e tipos de valores que desejam para seus filhos. Coletou-se dados de 756 participantes (EUA, n = 519, Brasil, n = 237), pais ou responsáveis por alunos de 7 a 14 anos. Foram realizadas análise fatorial exploratória e confirmatória, medidas de invariância e estatísticas básicas como média, desvio padrão e correlação. Os resultados corroboram uma estrutura de quatro fatores do instrumento e os padrões autorrelatados nas duas culturas. O instrumento pode auxiliar em pesquisas transculturais sobre o desenvolvimento de valores e captar diferenças entre culturas.
Social support network, functional capacity and mental health in older adults
Authors: Rabelo Doris Firmino , Pinto Juliana Martins
Published: January 2024

Abstract This study aimed to describe the characteristics of the social networks of older adults and to assess associations between social support, functional capacity and mental health. The sample consisted of 134 community-dwelling older adults, assessed in terms of their social network through the Minimum Map of Older Adult Relationships; functional capacity for performance in activities of daily living; depressive symptoms, assessed through the Geriatric Depression Scale and; anxiety, assessed through the Beck Anxiety Inventory. Cluster analyses were performed. The social network was characterized by being informal, functioning as affective support that occurs through visits. Social support perceived as insufficient was more frequent in men, in those who were dependent regarding instrumental activities of daily living, and in those with anxiety and depressive symptoms. Reduced social support networks and lack of support were associated with limitations in functional capacity and worse mental health, sparking debate about the centrality of the family in the provision of support.
Escala de Estratégias de Enfrentamento para Pacientes Oncológicos: Desenvolvimento de uma Medida
Authors: Pereira Fillipe Rodrigues Santos , Sá Lucas Guimarães Cardoso de , Silva Mariana do Nascimento , Santos Alice Parentes da Silva
Published: January 2024

Resumo O objetivo desse estudo foi desenvolver um instrumento capaz de avaliar o enfrentamento de pacientes oncológicos. Foram construídos 112 itens que passaram por análise teórica de juízes especialistas e pré-teste com o público-alvo. Os 42 que restaram após essas etapas foram respondidos por 392 pacientes oncológicos. A análise de validade de estrutura interna foi realizada por análise fatorial exploratória. Denominada como Escala de Estratégias de Enfrentamento para Pacientes Oncológicos (E3PO), os resultados indicaram uma estrutura de 20 itens divididos em dois fatores que explicam 36,05% da variância total. Engajamento no Tratamento, 14 itens (confiabilidade composta de 0,83), avalia compromisso orientado para mudança do estressor. Reações Emocionais, seis itens (confiabilidade composta de 0,75), avalia enfrentamento baseado na expressão de sentimentos negativos advindos do estressor. A E3PO pode futuramente auxiliar na elaboração de planos terapêuticos e avaliação de intervenções comportamentais que tenham como foco o desenvolvimento ou melhoramento do enfrentamento ao câncer.
La radiación solar en extremo ultravioleta: implicaciones en la atmósfera de la Tierra
Authors: Rodríguez-Gómez Jenny Marcela
Published: January 2024

La radiación solar, específicamente la irradiancia en Extremo Ultravioleta (EUV) es importante porque influencia directamente la atmósfera de la Tierra, por ejemplo el sistema de la Ionosfera-Termosfera-Mesosfera (ITM). Las variaciones en la densidad atmosférica dependen de la irradiancia solar, el viento solar y las tormentas geomagnéticas, generando calentamiento en la atmósfera neutra. Así consecuentemente los satélites que vuelan en regiones altas experimentan un incremento en la fuerza de arrastre. Estos efectos disminuyen la vida útil de los satélites e introducen significativos errores en el seguimiento orbital. Por lo tanto medidas confiables de la irradiancia solar en extremo ultravioleta en largas escalas de tiempo observadas o/y desde modelos, son necesarias para entender su efecto en la atmósfera alta, específicamente para mejorar las predicciones de la densidad neutral en la termosfera, evitar pérdidas de los satélites debido al arrastre y evitar colisiones.
Growth, gas exchange and essential oil production of Mentha spicata L. under water deficiency1
Authors: Batista Rita de Cássia Monteiro , Carvalho Josabete Salgueiro Bezerra de , Coqueiro Danilo Rosendo , Aquino Pedro Gregório Vieira , Alves Leonardo Zacarias
Published: January 2024

ABSTRACT Drought stress is a critical factor affecting plant growth and development. Understanding the effects of drought on the physiology of medicinal plants can contribute to the implementation of better water management techniques and promote a sustainable production. This study aimed to evaluate the influence of water stress on the growth and development of Mentha spicata L. plants. A completely randomized design was used, with two water conditions: irrigated and non-irrigated. The water deficit negatively affected the dry weight of roots and shoots, with a decrease in the transpiration rate and chlorophyll content, potentially impairing the photosynthetic activity. However, the essential oil production was not affected in plants subjected to water deficiency, indicating that the essential oil production may be more resilient to drought stress in this species.
Effect of shading and growing season on the agronomic performance of jambu1
Authors: Silva Andressa de Oliveira , Barral Deiviane de Souza , Rosário Isabelle Caroline Bailosa do , Santos Lucas da Silva , Gomes Rafaelle Fazzi
Published: January 2024

ABSTRACT The jambu (Acmella oleracea) production can be influenced by the growing season and light available for metabolic processes. This study aimed to assess the agronomic and physiological performance of two jambu varieties, under different shading levels, during the winter and summer of the Brazilian Amazon. Two random block experiments were conducted, in a 2 x 4 factorial scheme, consisting of two jambu varieties (yellow and purple flower) and four shading levels (0, 30, 50 and 70 %), with four replications. Physiological, growth and yield traits were assessed. There was no significant interaction between treatments and growing seasons (Amazon winter and summer) for growth or yield traits, nor between treatments for the physiological characteristics. The cultivation without shading screen can increase the shoot dry weight of both varieties; the yellow flower variety exhibited early-onset flowering regardless of the shading screen used; the “Amazon summer” growing season increased the jambu yield by 33 %, while the 70 % shading reduced the net photosynthetic rate, consequently not favoring the vegetative development of the jambu plants. As such, it is recommended that the yellow and purple flower jambu varieties be grown without shading screen in the Amazon summer.
A PROTEÇÃO DOS DADOS SENSÍVEIS NA PESQUISA CIENTÍFICA, MIGUEL REALE E A INDIVIDUALIDADE DA PESSOA
Authors: de Carvalho José Maurício , dos Santos Vanessa Eugênia
Published: January 2024

This work considers the importance of preserving the anonymity of the research subject, protecting the data that he has publicly exposed. This is because its exposure may harm it in different situations. Therefore, it is the responsibility of the researcher to protect two sensitive data that weaken the person. The researcher's commitment is signed through the TCUD, an instrument in which it undertakes to guarantee the confidentiality of personal data obtained by researchers, ensuring the participation of the person in a free and informed manner. We try to indicate the legislation that guarantees the protection of two given people and even those of the National Health Council that takes care of this protection in scientific research. We also present the ethical reasons that support this protection.Keywords: Industrial property litigation. Precautionary procedures. Proof. Procedural means of obtaining evidence. Procedural means of preserving evidence. Procedural advertising. Decisional advertising.
Auroville, the city of Nature's Yoga: material, spiritual and sustainable architecture and urbanism
Authors: Cunha Pedro Henrique Azalim
Published: January 2024

This article aims to reflect on ongoing research that investigates cosmopolitical and spiritual practices in Auroville, an urban experience in southern India that emerged from the teachings of Sri Aurobindo (1872-1950), creator of Integral Yoga, philosopher, yogi, poet and icon of the nationalist struggle. This city adopts sustainable urban planning and architecture techniques that seek to be an example for the creation of a new human being integrated into the cosmos, living a collective life centered on the Yoga of Nature. Auroville aims to be "the city the world needs" and to inspire other cities towards sustainable practices, enabling a transformation in the world. The city center is a temple dedicated to concentration and meditation, but not linked to any religion. Ecological and spiritual practices act as guidelines for a more balanced and natural collective life, enabling an integration of material-spiritual architecture and urbanism with nature. The methodology used included in-depth interviews and participant observation during the field visit. The one-month experience in Auroville showed that, despite its many positive aspects, the contradictions inherent in such an experience are inevitable. The concentration of national and international resources, the recovery of the soil and forest, the solutions to guarantee drinking water supplies, roads, paths and infrastructure in general have changed the entire region. Spiritual tourism and commercial migration have contributed to a process of micro-regional real estate speculation. An internal conflict over the direction of the city and its surroundings, over the very integration of city-nature, is worrying Aurovillians today.
T-1 TICK FIELD SAMPLING v2
Authors: Consortium REDI-NET
Published: January 2024

This protocol describes tick field sampling.
A standard pipeline for processing short-read sequencing data from Littorina snails v2
Authors: Reeve James , Ghane Amin
Published: January 2024

This protocol explains the default pipeline we recommend for analysing short-read data for Littorina marine snails. The pipeline was designed based on our experience processing WGS data, and careful consideration of the available tools. We are presenting this protocol as a suggestion of how Littorina sequencing data can be processed, and as a template for building more specific pipelines. Our hope is that through writing this protocol we can have more consistency among projects, leading to greater transparency for collaborators and providing a template which could be used to build pipelines for other organisms.
Preservation method for long-term storage of fluorescently labeled cells for microscopy v1
Authors: Robertson Jacob , Garza Erin
Published: January 2024

This method can be used to preserve fluorescently labeled bacterial cells for long-term storage before imaging on a fluorescent microscope. Using this protocol, samples can be saved at 4°C for weeks-months while maintaining strong, easily detectable fluorescence and cell integrity.
GENERATION Z’s PERCEPTION OF JAVANESE ORAL TRADITION OF MYTH AND TABOO ORA ILOK IN JAVANESE SOCIETY
Authors:   Institut Teknologi Bisnis AAS Indonesia, Fitria Tira Nur
Published: January 2024

The various myth and taboos of ora ilok are familiar among several Javanese groups. The objective of this research is to understand generation Z’s perception of the Javanese myth and taboo ora ilok in Javanese society. This research employs the descriptive qualitative method, involving 76 respondents from various regions of Java such as Central Java, East Java, West Java, and the Special Region of Yogyakarta. The respondents were born between 1996 and 2005. Results show that the majority of respondents do not believe in the ora ilok myths. However, there is a different opinion from Generation Z. Some consider myths as a joke and treat them with scepticism, while a few still believe in these myths, viewing them as rules that must be followed, with potential repercussions for breaking them. Meanwhile, none of the respondents believes in the ora ilok taboo. Ora ilok is a Javanese term used to describe something which is not good and unethical due to its associated prohibitions. It is unwritten and serves as important rules of politeness, serving as a reminder for children, teenagers, and adults. There are values behind the word ora ilok, but the elders usually emphasize its negative consequences on the physical and mental well-being of those who violate these rules. This serves as a reminder for the Javanese to behave politely and respect the rights of others. However, there is a difference in the judgment of generation Z. Many of them no longer believe in ora ilok, while some view it as a joke and treat it with scepticism. However, these myths and taboos are gradually eroding in the new culture of this era.
COLLECTION-BASED RESEARCH ON A KAMPILAN SWORD IN JAMBI PEOPLE’S STRUGGLE MUSEUM
Authors:   Faculty of Teacher Training and Education, Universitas Jambi, Leihitu Irsyad , Hariadi Ujang ,   Regional Technical Implementation Unit (UPTD) Siginjei Museum, Jambi
Published: January 2024

This article discusses the kampilan sword in Jambi People’s Struggle Museum. Kampilan is a traditional weapon originating from the Philippines but has spread to several regions in Indonesia, including Jambi. The kampilan sword collection is often overlooked, and there is not much information regarding these objects, despite the museum’s primary function is research and communication. Therefore, we conducted a study of a collection of kampilan swords to explore information related to these objects, allowing the museum to utilize and develop them in the future. The research model was based on the material culture study, using the social life of things and object biography approaches. Results indicate that, through these two approaches, new information and narratives about kampilan swords were successfully compiled. In the future, the museum can use these narratives to create new programs, create meanings and ideas related to struggle, and serve as the first step towards further research.
Spectrophotometric Assay of Prothipendyl through the Determination of Its Sulfoxide
Authors:   Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland, Mozgova Olena , Blazheyevskiy Mykola ,   Department of General Chemistry, National University of Pharmacy, Kharkiv, Ukraine, Kryskiw Liubomyr ,   Department of Pharmaceutical Chemistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Kucher Tetyana ,   Department of Pharmaceutical Chemistry, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Moroz Valeriy ,   Department of General Chemistry, National University of Pharmacy, Kharkiv, Ukraine
Published: January 2024

A new difference spectrophotometric method for the analysis of prothipendyl hydrochloride in commercial pharmaceutical preparations has been proposed. The method includes oxidation of an aliquot of the drug solution with potassium caroate to form the corresponding sulfoxide (ε278 = (13.69 ±0.01)×103 L mol/cm) and subsequent measurement of the optical density of the solution at 278 nm compared to that of the unoxidized drug solution of equal concentration. The graph of Beer's law for prothipendyl hydrochloride shows that the ΔA values measured at the corresponding wavelength are proportional to the concentration of the drug in the concentration range of 3.2-60 µg/mL. The characteristics of the curve calibration curve of the linear regression equation were as follows: ΔА = (0.0342±0.0006)C + (0.0501±0.025) (where C in μg/mL). The resulting difference in absorbance is independent of the presence of excipients and degradation products in the formulation. A new spectrophotometric technique has been developed and the possibility of quantitative determination of prothipendyl hydrochloride monohydrate in Dominal® tablets of 40 mg has been demonstrated. RSD =1.4% (δ= – 0.42%).
FEATURES OF THE LIPID PROFILE AND ADIPOSE TISSUE IN PATIENTS WITH CAROTID ARTERY STENOSIS ON THE BACKGROUND OF CORONARY ARTERY DISEASE
Authors: Tsygankov Denis A. , Polikutina Olga M.
Published: January 2024

Highlights

Intra-abdominal adipose tissue thickness (IAAT) was statistically significantly greater in patients with hypertriglyceridemia compared to patients with normal triglyceride levels. Linear regression analysis confirmed the following findings: the greater the thickness of IAAT and preperitoneal fat thickness (PFT), the higher the levels of triglycerides and very-low-density lipoproteins.

Abstract

Aim. To assess the lipid profile and distribution of adipose tissue (based on ultrasound parameters) and their role in the development of carotid artery stenosis in patients with coronary heart disease (CHD).

Methods. Ultrasound parameters of adipose tissue in 125 patients, diagnosed with coronary heart disease (CHD), were studied. The average age of the patients was 68 (61.0; 74.0) years old. The sample was represented predominantly by males (58.4%).

Results. It was determined that in patients who did not reach the target levels of triglycerides (TG), the thickness of the IAAT is 15 mm more than in patients with the adequate level of this indicator (p = 0.031). Subcutaneous adipose tissue (SAT) values also exceeded the values ​​in individuals with low HDL levels (p = 0.050), in contrast to patients with normal HDL. Linear regression analysis (after adjusting for gender and age) showed that the increase in IAAT thickness was associated with the increase in TG (b = 0.002, p = 0.028) and VLDL (b = 0.001, p = 0.023). It was also found that only 43.4% of the examined individuals received lipid-lowering therapy, and 17.3% received an adequate dose of statins (reached the target LDL values).

Conclusion. No statistically significant patterns were found between the achievement of lipid targets and the presence of carotid stenosis. An extremely low percentage of patients taking adequate lipid-lowering therapy (17.3%) was determined, and the proportion of the people with carotid stenosis who reached the target levels of total cholesterol was 58.4%, TG – 79.3%, HDL – 31.7%, LDL – 12.2%. The thickness of the IAAT is statistically significantly higher in individuals with hypertriglyceridemia, in contrast to patients with normal TG levels. The tendencies towards statistical significance of PFT indicators in individuals with hypertriglyceridemia, minimum and maximum SAT values, depending on the level of HDL, were determined. Linear regression analysis confirmed the data obtained: the higher the thickness of IAAT and PFT, the higher the levels of TG and VLDL.