bluuebunny/crossref_metadata_2025 huggingface dataset:
The Militarization of Russian foreign and security policy and its possible impact on global security
Authors: Kaszuba Malina
Published: February 2020

The transformation of the Russian foreign and security policy based on a more courageous use of military potential is a fact. Over the past several years, Russia has moved from articulating its interests to their enforcement with the use of military force. This article focuses on analyzing this process and identifying its potential consequences for global security. The conclusions drawn by the author, based on the conducted research, allow to state that the armed forces are and will be an important instrument of the Russian foreign and security policy. This does not mean, however, that the Russian Federation will strive for an armed conflict posing a threat to international security.
SYNTHETIC MEASUREMENT USED AS ASSESSMENT OF SPATIAL DISPARITIES OF THE NATURAL ENVIRONMENT
Authors: Przybytniowski Jarosław Wenancjusz , Dziekański Paweł
Published: February 2020

One of important factors of attractiveness of a region is its natural environment, namely a set of natural elements which are of interest to a tourist. In terms of economy, it is a source of raw materials and energy, it ensures geographical space, business opportunities and a place to live and relax. The aim of the research included in this article is to indicate the possibility of using synthetic measurement to recognize spatial disparities of the natural environment on the basis of selected diagnostic features of 102 municipalities of the Świętokrzyskie Voivodeship. The data presented in this article refer to 2009, 2012 and 2015 and come from the Local Data Bank. The following variables were selected: the total use of household water per one inhabitant, the distribution network per 100 km2 - water pipe system, the distribution network per 100 km2 – sewage system, woodland area, areas protected by law, protected monuments. The elements indicated refer to entities which function and operate in a territorial unit. The methods presented enable us to identify areas of human life (or human impact on the environment) of higher/lower efficiency (which depends on the level of synthetic measure) and, then, programme their support from public funds within the framework of the regional policy.
MICROBIAL CONTROL IN WHITE CACTUS PEAR WITH BIOPOLYMERIC COATING OF CHITOSAN, CANDELILLA WAX AND THYME ESSENTIAL OIL
Authors: Valle-Ortiz Daniel J. , Gómez-Cruz Adalberto , Hernández-Fuentes Alma D. , Valle-Guadarrama Salvador
Published: February 2020

White cactus pear (Opuntia albicarpa L.) undergoes decay by pathogens in postharvest, which limits its shelf life. The objective of this study was to evaluate coatings based on chitosan (Q), candelilla (Euphorbia antisyphilitica Zucc.) wax (Cw) and thyme (Thymus vulgaris L.) essential oil (Eo) to reduce microbial development on the cactus pear and increase shelf life. Emulsions based on Q, Eo, and Q+Eo were applied on freshly harvested cactus pear fruits, which were stored for 18 days at 22 ºC. Treatments with Q also incorporated Cw. Controls were uncoated fruits (Ct). Microbial inhibition was assessed through bacterial counting in culture plate, in addition to the appearance of the fruit on a visual scale 1 to 5, where 1 corresponded to appalling and 5 to excellent. Fruits with the Q+Eo treatment had an appearance close to 4 at the end of the storage, followed by those with Q, Eo, and T, which obtained a score of 1. The lowest weight loss occurred when Cw was used. With a coating of Q (2 %), Eo (2000 ppm) and Cw (5 %) microbial growth was reduced by 98.4 %, allowing a shelf life of at least 18 days at 22 ºC, with good appearance and low weight loss in fruits.
LA SOLUCIÓN NUTRITIVA MODIFICA EL CRECIMIENTO DE DOS ESPECIES DE ORQUÍDEAS
Authors: Jiménez-Peña Nadia , Sandoval-Villa Manuel , Volke-Haller Víctor H. , Pedraza-Santos Martha , Colinas-León Ma. Teresa
Published: February 2020

Las orquídeas (Orchidaceae) se desarrollan en una gran variedad de condiciones ambientales, por lo que tienen requerimientos específicos de nutrición. En la nutrición de orquídeas existe desconocimiento de los efectos de los fertilizantes y de su uso a lo largo del ciclo de estas plantas. El objetivo de esta investigación fue estudiar el efecto de tres soluciones nutritivas sobre el desarrollo y crecimiento de Laelia autumnalis y Paphiopedilum insigne. El experimento se realizó en un periodo de 27 meses en condiciones de invernadero. Las variables evaluadas fueron número de hojas, área foliar, peso fresco y seco total de la planta, de raíz y de hoja, y lecturas SPAD en hojas maduras; además, en L. autumnalis se evaluó el número de pseudobulbos, grosor y largo de pseudobulbos, así como el peso fresco y seco de éstos. Se encontró que en L. autumnalis la solución de Steiner incrementó el número de hojas (100 %), pseudobulbos (133 %), área foliar (80 %), peso fresco total (78 %) y peso seco total (125 %), en comparación con las plantas tratadas sólo con agua (testigo). En P. insigne la solución Hoagland-Arnon mejoró el crecimiento vegetativo, incrementó el número de hojas (65 %), área foliar (83 %), lecturas SPAD (79 %), peso fresco total (33 %) y peso seco total (27 %), en comparación con las plantas testigo. Los resultados demuestran que las soluciones nutritivas influyen positivamente en el crecimiento de las dos especies de orquídeas y que cada especie tiene requerimientos nutrimentales particulares; asimismo, los resultados podrían ser de utilidad en programas de conservación y aprovechamiento de estas especies.
Green Life Style Sebagai Mediator Ecoliteracy dan Green Product Knowledge Terhadap Keputusan Pembelian Konsumen di Kota Ambon
Authors: Saleky Saul Ronald Jacob , Souisa Wendy
Published: February 2020

To meet the needs and desires, consumers make decisions on the purchase of certain products. In making decisions, consumers are affected and consider many factors. This study aims to examine and analyze the effect of ecoliteracy and green product knowledge to the green lifestyle and purchasing decisions, either directly or indirectly. These results indicate that all independent variables have an effect on the dependent variable. Eco-literacy and green product knowledge have a direct influence on the green lifestyle and purchasing decisions. Furthermore, green lifestyle has a direct influence on consumer purchasing decisions in Ambon City. Similarly eco-literacy and green product knowledge has no direct influence on purchasing decisions through a green lifestyle. These results indicate that the directly effect of eco-literacy and green product knowledge was greater than the indirectly effect of through a green lifestyle. This means that the consumer's decision to buy a green product is more influenced by eco-literacy and green product knowledge than green lifestyle. Therefore, in order to encourage consumers more broadly to make purchases of green product, it would be better and easier for marketers and or manufacturers to enhance the eco-literacy and green product knowledge of the consumer.
Financial and Economic Analysis Irrigation Area Development Bajayu – Serdang Bedagai
Authors: Nasution Mahliza , Rahmad Dedi , Rusyanto Rusyanto
Published: February 2020

Serdang Bedagai is one of the rice granaries in North Sumatera Province, but its agricultural potential has not been well managed due to lack of water for irrigation, especially in the dry season.With bajayu weir construction, is expected to improve water demand forclean water and irrigation for agricultural processes can be developed and managed bygood.The cost of construction of the dam construction is very large, so it needs to be reviewed if the benefits and income generated are proportional to the costs and losses incurred.The final goal of this research is to conduct financial and economic analysis in the construction of bajayu weir.This study uses financial and economic analysis using Net Present Value (NPV), Internal Rate of Return (IRR), Benefit cost Ratio (BCR) indicators and also analyzes sensitivity due to cost changes.Optimal handling is estimated after 10 years, so within that time the benefit increases linearly until the 13th year and will remain from year 13 to the next.From the calculation of finance development of bajau irrigation area obtained NPV = Rp.1.778.603.070.507,62-, IRR = 27%, BCR = 4.6.And from the economic calculation of the area of irrigation bajayu obtained NPV = Rp.1.235.038.404.979,95-, IRR = 32% BCR = 6.92.And calculation of sensitivity analysis has also been done to change of cost and benefit equal to ± 5% and ± 10% for financial and economic analysis indicate that project plan still very feasible.
Analisis Rangkaian Full Wave Rectifier dengan Filter Kapasitor, Pembagi Tegangan, Buffer dan Penguat Differensial pada Sensor Arus
Authors: Giyantara Andhika , Mudeng Vicky , Ramadhani Rizky , Wulandari Rizky
Published: February 2020

Abstrak

Penelitian ini menyajikan perancangan dan analisis sebuah sensor arus yang terdiri dari rangkaian penyearah gelombang penuh dengan filter kapasitor, pembagi tegangan, buffer, dan penguat diferensial. Metode yang digunakan untuk mengukur nilai arus pada sensor adalah dengan menetapkan salah satu resistor pada rangkaian pembagi tegangan sebagai resistor referensi (Rs). Metode ini didasarkan pada hukum Ohm dalam menentukan nilai arus yang melalui suatu jalur. Hasil percobaan yang dilakukan telah membuktikan teori yang disajikan.

Kata Kunci: metode resistif, pengukuran arus, rangkaian sensor arus.
Dietary quercetin supplementation does not increase maximal oxygen uptake and physical work capacity
Authors: Freese E.C. , Cureton Kirk
Published: February 2020

Aim: Th e purpose of our study was to use a time-series design to investigate the eff ect of dietary quercetin supplementation on peak oxygen uptake (VO2peak) and physical work capacity. Methods and organization of the study: Nine recreationally-active men and women completed a treadmill-running graded exercise test (GXT) weekly (excepting wk 8) for 14 weeks. During the fi rst 3 and last 3 weeks, no quercetin supplementation was administered. During weeks 4-11, subjects ingested four soft Q-chews (Nutravail Technologies) per day containing quercetin (1 g/d), vitamin C, vitamin B3 and folic acid. A control group of 5 men were also tested during the fi rst and last week. Research results: VO2peak and test time remained stable throughout the 14 weeks at approximately 3.5±1.1 L/min and 6±1.6 min. Using a one-way repeated measures ANOVA, there was no signifi cant diff erence among means (P > 0.05) for either measure. Th ere was no trend for individual or mean values to increase above baseline during the treatment period. No changes occurred in the control group. Conclusions: We conclude that dietary quercetin supplementation with 1 g/d for 8 wk in non-endurance-trained men and women does not increase VO2peak or physical work capacity. Keywords: exercise, fl avonoids, muscle oxidative capacity, oxygen consumption
Smart SDN Management of Fog Services
Authors: Frohlich Piotr , Gelenbe Erol , Nowak Mateusz P.
Published: February 2020

We present a smart Service Manager whose role is

to direct user requests (such as those coming from IoT devices)

at the edge towards appropriate servers where the services they

request can be satisfied, when services can be housed at different

Fog locations, and the system is subject to variations in workload.

The approach we propose is based on using an SDN controller as

a decision element, and to incorporate measurement data based

machine learning that uses Reinforcement Learning to make the

best choices. The system we have developed is illustrated with

experimental results on a test-bed in the presence of time-varying

loads at the servers. The experiments confirm the ability of the

system to adapt to significant changes in system load so as to

preserve the QoS perceived by end users.
About the condition of the soils and vegetation of urbanized territories of Ufa city
Authors: Churagulova Z. S. , Sultanova R. R. , Mingazheva A. M.
Published: February 2020

Purpose. Study of the soil, soil cover and vegetation of the forest park of the city of Ufa. Methods. Soil studies were carried out at a scale of 1: 2000 on a cartographic basis with contours, using standard techniques. Analytical work was performed using the methodological guidelines and GOSTs adopted in soil science and forest science in the Republican Forest Soil and Chemical Laboratory of the MLH RB. Results. Forest coverage of the forest park is 84%. The average age of the park's plantations is 54 years old. This plantings IV-VII age classes. 20% - ripe and overmature stands. The average bonitet of the forest park is 11.7. Average fullness - 0.8. The main soil cover of the park is gray, dark gray, typical structurally differentiated, dark brown-brown, typical texturally differentiated, typical lithozems. In the upper soil layer, the coefficient of structure is 5.2, in the underlying - 4.3. Recreational load of the soil leads to a sharp deterioration of their structure. Conclusion. The limiting factors limiting the state of stands are the shortened thickness of the humus horizon, the heavy particle size distribution, the neutral and weakly alkaline reaction of the soil environment. Plantings are adversely affected by anthropogenic factors, infection by diseases and pests. Reconstruction of growing, placement of new tree species, shrubs and bushes, including introducents, is recommended considering the soil conditions. The data of agrochemical parameters will allow to create optimal nutrition conditions for the formation of various compositions of trees and shrubs.
Assessment of phytopathological state of woody plants by ultrasound diagnostics
Authors: Korotkov O. I. , Gerasimchuk V. N. , Belyakov V. A. , Gavrilenko Y. A. , Gardt D. S. , Kanaeva S. A. , Kutaytsev G. V. , Logachev I. O.
Published: February 2020

The state of the wood trunk tissue of trees Cupressus sempervirens 'Stricta', Morus nigra L., Magnólia grandiflóra L., Carpinus orientalis Mill., growing in the Park of the Educational center "Sirius" (Sochi) was determined with the use of complex acoustic ultrasound tomography ARBOTOM® ABT05-S. It was revealed that these species were characterized by a significant differentiation in the degree of damage to bracket fungi. Low level of phytopathogenic damage was observed in Carpinus orientalis . The trunk wood of Morus nigra was characterized by the highest rates of phytopathogenic damage. The negative impact of bracket fungi is one of the most significant factors that reduce vital functions and reduce the life of many species of woody plants. Phytopathogenic damage to wood and trunk rot formation and voids have an impact on the growth and development of plants, reducing their life time, and can lead to death and fall of a tree, which within the urban environment is a potential danger to people.
Content of essential elements in fig fruits of foreign selection cultivars
Authors: Dunaevskaya E. V. , Shishkina E. L.
Published: February 2020

Objective. Fruits of figs from the collection of the Nikitsky Botanical Gardens: Figue Grise, Randino and Fig Blanche were studied for use as raw material for health products. Methods. The content of elements was determined using AAS “Kvant 2MT” in the emission mode (K) and in the absorption mode (Ca, Mg, Fe, Mn, Cu, Zn). Results. The content of seven essential elements in the fruits of two generations (yields) was studied for the first time. It was revealed that the fruits of the studied fig cultivars contain high quantities of potassium, calcium and magnesium, and satisfactory quantity of ferrum. In the first generation of fruits, the ferrum content is higher by 72-73%, potassium by 4.5-18.4%, than in the second generation of fruits. The fruits of the second generation accumulate more calcium (by 28-31%), magnesium (by 11.6-26.8%), zinc (by 9.9-23.3%) and manganese (by 5.2-17.7 %). Conclusion. The cultivar of early maturity Fig Blanche, in which the fruits of two generations are characterized by the maximum of three cultivars of potassium (15970 mg / kg in the I-st generation, 13020 mg / kg - in the II-nd generation), magnesium (2520 mg / kg and 2810 mg / kg), ferrum (15.54 mg / kg and 9.05 mg / kg), zinc (1.51 mg / kg and 1.69 mg / kg), cuprum (2.24 mg / kg and 1.93 mg / kg) and manganese (2.38 mg / kg and 2.51 mg / kg) content.
A Statistics–Respecting Bijection Between Permutation Matrices and Descending Plane Partitions Without Special Parts
Authors: Fulmek Markus
Published: February 2020

We present a bijection between permutation matrices and descending plane partitions without special parts, which respects two of the statistics considered by Mills, Robbins and Rumsey, and an additional statistic  considered by Behrend, Di Francesco and Zinn–Justin.
Juglone Attenuates Sepsis-Induced Acute Lung Injury via Suppression of the TLR4/Nf-κb Pathway
Authors: Nan Qiu , Xinmei Xu , Yingying He , Chengfen Fan
Published: February 2020

Sepsis, with high mortality, induces deleterious organ dysfunction and acute lung injury. Natural compounds show protective effect against sepsis-induced acute lung injury. Juglone, a natural naphthoquinone, demonstrates pharmacological actions as a pro-apoptotic substrate in tumor treatment and anti-inflammation substrate in organ injury. In this study, the influence of juglone on sepsis-induced acute lung injury was investigated. First, a septic mice model was established via cecal ligation and puncture, and then verified via histopathological analysis of lung tissues, the wet/dry mass ratio and myeloperoxidase activity was determined. Cecal ligation and puncture could induce acute lung injury in septic mice, as demonstrated by alveolar damage and increase of wet/dry mass ratio and myeloperoxidase activity. However, intragastric administration juglone attenuated cecal ligation and puncture-induced acute lung injury. Secondly, cecal ligation and puncture-induced increase of inflammatory cells in bronchoalveolar lavage fluid was also alleviated by the administration of juglone. Similarly, the protective effect of juglone against cecal ligation and puncture-induced acute lung injury was accompanied by a reduction of pro-inflammatory factor secretion in bronchoalveolar lavage fluid and lung tissues. Cecal ligation and puncture could activate toll-like receptor 4/nuclear factor-kappa B signaling pathway, and administration of juglone suppressed toll-like receptor 4/nuclear factor-kappa B activation. In conclusion, juglone attenuated cecal ligation and puncture-induced lung damage and inflammatory response through inactivation of toll-like receptor 4/nuclear factor-kappa B, suggesting a potential therapeutic strategy in the treatment of sepsis-induced acute lung injury.
Current possibilities for studying of Wilson's disease ultrasound manifestations in children
Authors: Dykan Iryna , Tarasyuk Borys , Lukyanova Iryna , Korobko Victor , Soloduschenko V. , Andruschenko Iryna
Published: February 2020

36 cases of Wilson's disease were examined: 24 boys and 12 girls; 4 – with manifestations of acute liver failure. Control group consist of 19 children. Ultrasound examination of abdominal organs was performed. The structure of the liver was evaluated by the ASQ program, and liver stiffness – by elastography. A variety of ultrasound manifestations were determined: hepatomegaly, increased echogenicity of the parenchyma, presence of small focal formations, seal of the liver capsule and ascites (in acute cases). Parenchyma stiffness was 7.5-8.9 kPa (F1-F2 fibrosis). ASQ showed uniform staining of the liver parenchyma
Ileo-ileal intussusception secondary to an inflammatory fibroid polyp, a case report and a literature review.
Authors: Medina Velasco A , de la Plaza Llamas R , Arteaga Peralta V , López Marcano AJ , González Sierra B , Díaz Candelas DA , Sastre Borregón B , Latorre Fragua R , Ramia Ángel JM
Published: February 2020

Introducción: la intususcepción es el deslizamiento de un segmento de tracto gastrointestinal hacia otro distalmente adyacente, pudiendo alterar el tránsito gastrointestinal y su vascularización. Es más frecuente en niños y raro en adultos (5-16%), representando en estos últimos 1-5% de los casos de obstrucción intestinal. Una rara causa de esta es el pólipo fibroide inflamatorio (PFI). Presentamos un caso y revisamos la literatura.

Material y Métodos: se trata de un caso de intususcepción íleo-ileal causada por un PFI en una mujer de 26 años y realizamos una búsqueda en la literatura (actualizada el 9 de febrero de 2018). Como criterios de inclusión se seleccionaron aquellos pacientes con cuadros de intususcepción de intestino delgado por PFI. Se excluyeron los casos en otras localizaciones.

Resultados: la mediana de edad fue de 45 años con un rango intercuartilítico (RI) de 35-58 años, siendo más frecuente en mujeres (55%). La localización más frecuente de los PFI el íleon. La duración de los síntomas hasta la valoración hospitalaria tuvo una mediana de diez días (RI 3-45 días), presentando una masa palpable abdominal en 22 casos (22%). La tomografía computarizada fue la prueba más utilizada en el diagnóstico. En el tratamiento quirúrgico, la técnica más realizada fue la resección y anastomosis de intestino delgado por laparotomía. La mediana del tamaño del PFI fue de 3,5 cm (RI 3-5 cm).

Discusión y conclusiones: la intususcepción causada por PFI en intestino delgado ha sido descrita en 99 ocasiones en la literatura revisada, considerándose un hallazgo excepcional.
The future of education in surgery. How are new technologies and social media contributing to the education of medical students and surgical residents?
Authors: Blanco Colino R
Published: February 2020

Las nuevas tecnologías y las redes sociales hoy en día forman parte de la formación médica en diversos ámbitos. Los cambios que veremos en la cirugía y el cambio generacional de los futuros cirujanos influirán en la manera en que la revolución tecnológica forme parte de la cirugía. En este artículo se revisan las nuevas condiciones de futuro que se afrontarán desde el mundo quirúrgico, la generación que será la base de dichos cambios, y las contribuciones, limitaciones y beneficios que las nuevas tecnologías pueden aportar.
Effects of Smoking and Lipid Profile of the Patient on the Onset and Maintenance of Periodontal Disease
Authors: Ciavoi Gabriela , Tirb Alina , Bechir Edwin Sever , Bechir Farah , Suciu Ilinca
Published: February 2020

The purpose of our study is to determine the correlation between the effects of smoking, triglycerides and cholesterol (total, HDL, LDL) and periodontal disease. 90 patients, smokers diagnosed with periodontal disease and 30 nonsmoker patients (control group), in the age of 30-60 years, were studied. Patients were divided into 4 groups, each of 30 patients as follows: group I - smokers up to 10 cigarettes a day, group II-smokers between 10-20 cigarettes a day, group III-over 20 cigarettes a day, group IV- control group, nonsmokers. The values of the Silness-Loe dental plaque index (DPI), the gingival bleeding index (GI), the Periodontal Disease Index (PDI) -Ramfjord were noted in both the examined and control groups. The values of total cholesterol and HDL cholesterol showed statistically significant difference between the mean values �in the examined groups, while mean values �of HDL cholesterol in the second and third examined subgroups and control group were in higher range than the normal one. We concluded also that there is a relationship between smoking, the number of cigarettes smoked and the periodontal disease.
Facile Recoverable, Reusable and Efficient Heterogeneous Photocatalyst. Preparation and characterization of V2O5 added TiO2 polymer NCs
Authors: Muthupoongodi S. , Mitu Liviu , Linda T. , Shajan X. Sahaya , Balakumar S.
Published: February 2020

TiO2 and V2O5 added polymer nanocomposites (NCs) were prepared by solution cast method and characterized by UV-Vis-DRS spectroscopy, powder X-ray diffraction, FTIR and SEM analysis. These characterization studies were employed to investigate the structure, optical property, phase formation and morphology of the prepared polymer NCs. The photocatalytic activities of the NCs were studied by observing the degradation of model dyes congo red (CR) and rhodamine B (RhB) under 365 nm of UV-light irradiation. In addition the recyclability and reusability of the catalyst were also examined. The results showed that nearly 95 % congo red and rhodamine B had undergone degradation in 160 and 80 mins of reaction time respectively. The catalyst shows better recyclability and can be reused for at least 6 times. In particular V2O5 added polymer NCs shows better catalytic activity towards the degradation of organic dyes. In the photodegradation process the photo-induced holes were considered to be the dominant active species. The reported catalytic system is found to be a simple, reusable and effective model for the degradation of dye polluted effluent water.
Enhancing Education for Smoking Preventing and Smoking Cessation in Medical Personnel. A measure for a better health
Authors: Ianosi Edith Simona , Dantes Elena , Csipor Alpar , Szathmary Mioara , Socaci Adriana , Rusu Elena , Nemes Roxana Maria
Published: February 2020

Our work presents the smoking-related attitude, the methods for the development knowledge and antismoking commitment among health-care workers. We analyzed a 20 items questionnaire in 209 healthcare employees (specialists physicians, interns, medical assistants/nurses). Smoking is widespread among health professionals 34.7% comparing with the country average (28%). In the last 10 years smoking has declined in physicians -27.1% but remains constant in assistants 43.3% and nurses 46.3% (comparison with a previous study). Smoking is lower in young physicians and pulmonologists (by information achieved along courses and traineeships in Pulmonology Discipline). Smoking is predominant in males 55% vs 27.7% in females. Medical personnel�s knowledge about the harmful effects of smoking is still insufficient. 32% of smokers do not consider that smoking affects the health entourage. 20% report smoking in the hospitals. The methods used for providing antismoking activities in medical personnel were complexes: thematic conferences for physicians/nurses (6 in the last 4 years), 2 workshops for practical implementation the antismoking techniques, curricular courses (4 h/semester for the fifth-grade medical-students and third-grade assistants, 6 hours optional courses for all students) and by promoting the antismoking policy in our universities and pulmonology clinics. Medical personnel are a target group in the anti-smoking activity (like health promoters) considering the great potential for further education for large groups of patients.
Comparative Study of Drug Interactions in Benzodiazepine Associated Deaths
Authors: Chitescu Carmen Lidia , Lisa Elena Lacramioara , Fulga Iuliu , Paltenea Elpida , Moraru Monica , Georgescu Costinela Valerica , Vasile Ionut Claudiu
Published: February 2020

Due to their widespread use and availability, benzodiazepines are one of the most common classes of drug associated with both unintentional and suicidal drug deaths. The presented work, conducted at the Legal Medicine Service of Galati aims to expound the role of pharmaco-toxicological interactions between benzodiazepines and other psychoactive substances in drug related deaths. A retrospective analysis of 13 cases of fatal substances overdose was done. Parent drugs and metabolites detection and quantification in postmortem specimens were performed by HPLC-DAD, as part of a full forensic autopsy. The substance interactions were investigated and interpreted in the context of the available medical history. The study results emphases the acute toxicity of a given drug /alcohol combination.
The Learning Curve in Arthroscopic ACL Reconstruction. The impact on the Surgical Time and Postoperative Clinical Results
Authors: Negru Teodor , Mogos Stefan , Stoica Ioan Cristian
Published: February 2020

Rupture of the anterior cruciate ligament (ACL) is a common injury. The objective of the current study was to evaluate if the learning curve has an impact on surgical time and postoperative clinical outcomes after anatomic single-bundle anterior cruciate ligament reconstruction (ACLR) using an outside-in tunnel drilling hamstrings technique. The learning curve has a positive impact on surgical time but has no influence on postoperative clinical outcomes at short time follow-up.
Experimental Measurements in the Acquisition of Biosignals from a Neuronal Cell Culture for an Exoprosthesis Command
Authors: Moldovan Carmen , Dobrescu Lidia , Ristoiu Violeta , Firtat Bogdan , Dinulescu Silviu , Brasoveanu Costin , Ion Marian , Dobrescu Dragos , Gheorghe Roxana , Pascalau Ana Maria , Pogarasteanu Mark , Coculescu bogdan Ioan , Oproiu Ana Maria
Published: February 2020

This article presents experimental measurements performed in order to connect a neuronal cell culture to an exoprosthesis. The experiments focused on the biosignals� acquisition from the cell culture. A special gold-plated glass plate device was realized and several constructive variants were analyzed. A Olympus microscope with fluorescence and photo system was used. The acquisition of bio signals from the neuron culture is realized and described in the paper. The measurements were made in the sterile environment within the laboratory of Institute of Cellular Biology and Pathology. The measurements have been made for the pair of electrodes 1-1 at the edge of the glass plate.
Design, Synthesis and Molecular Docking of some Oxazolidinone Compounds
Authors: Pintilie Lucia , Stefaniu Amalia , Nicu Alina Ioana , Negut Catalina , Tanase Constantin , Caproiu Miron Teodor
Published: February 2020

A series of oxazolidinone compounds have been obtained and characterized by physico-chemical methods and antimicrobial activity against Staphylococcus Aureus ATCC 6538. For the synthesized compounds have been performed calculations of characteristics and molecular properties, using Spartan 14 Software from Wavefunction, Inc. Irvine, CA. and molecular docking studies using CLC Drug Discovery Workbench 2.4 software, to identify and visualize the most likely interaction ligand (oxazolidinone derivatives) with the receptor protein.
Biodegradability and Adaptability Studies of Geothermal Wastewater in a Biological Treatment Plant
Authors: Popescu Luisa Roxana , Dinu Cristina
Published: February 2020

The purpose of this study was to identify the optimal conditions for the operation of biological treatment plant by carrying out biodegradability tests for geothermal wastewaters with high salt content. The biodegradation tests for geothermal wastewaters were carried out in a discontinuous flow bioreactor. The phases of the biodegradation process were: adaptation of the biological sludge, control of the biological treatment process, experiments in the laboratory bioreactors (BATCH). The results of the biodegradability tests revealed that geothermal waters with high salt content influence the treatment process. The dilution of these waters with domestic water up to chlorine concentrations below 800 mg L-1, makes the purification process to have a good biodegradation yields for CCO-Cr (about 75%) and CBO-5 (about 72%). If these geothermal wastewaters are not diluted to concentrations lower than 800 mg L-1, the biological sludge after 6 days is mineralized, which makes the use of biological treatment plant to be impossible.
The Variation in Cholesterol and Triglycerides Levels and the Risk for Stroke in First Degree Relatives of Stroke Patients
Authors: Grosu Cristina , Mastaleru Alexandra , Costan Victor Vlad , Nita Otilia , Leon Constantin Maria Magdalena
Published: February 2020

Cerebrovascular diseases have become a leading cause of mortality and major invalidity throughout the world in the last years. The levels of cholesterol and triglycerides are among the modifiable risk factors for stroke. The intima media thickness (IMT) is a very good marker for subclinical atherosclerosis and also for predicting future cardio- and cerebrovascular events. The aim of this study was to determine correlations between the lipid profile and the value of the intima media thickness as a risk factor for stroke in first degree relatives of stroke patients. We evaluated a total of 176 subjects, selected by well defined criteria, divided into three groups: stroke patients, first degree relatives of stroke patients and a healthy control group. We measured weight, height and body mass index, the levels of cholesterol and triglycerides, and IMT by cervical ultrasound mode B, at the common carotid artery (CCA) and internal carotid artery (ICA) bilaterally. The mean values of lipids were in the normal range. However, in the stroke group, both cholesterol and triglyceride levels were increased compared to the other groups. The triglycerides level positively correlated with IMT in the CCA in both control and stroke patients, but this was not the case for cholesterol levels. Also, the increase in IMT in stroke patients correlated with an increase in IMT of their relatives. Further research is needed in order to elaborate a screening algorithm for primary prevention of stroke in first degree relatives of stroke patients.
Coenzime Q10. Comparative Study Active Substance versus Pharmaceuticals Products
Authors: Buciuman Cristina , Marian Eleonora , Tita Bogdan , Jurca Tunde , Chis Adriana , Vicas Laura
Published: February 2020

Coenzyme Q10 is a molecule which shows promising properties in the prevention and treatment of different disorders. It is mostly found in dietary supplements together with different excipients and other lipophilic vitamins that can influence the release profile of the active substance. This influence is due to the possible interaction of the active substance with the excipients present in the drug composition. In this regard, this paper presents a comparative study between coenzyme Q10 - active substance and three of the corresponding pharmaceutical products: P1, P2 and P3. The four compounds were characterized simultaneously by thermal analysis, FT-IR spectroscopy and X-ray powder diffraction patterns.
Bulk Liquid Membranes for Separation and Recovery of Pharmaceutical Products
Authors: Serban Ecaterina Anca , Diaconu Ioana , Ruse Elena , Batrinescu Gheorghe , Nechifor Gheorghe , Lazar Mihai Nita
Published: February 2020

In this present paper the behavior of two important pharmaceutical compounds, namely: nicotinic acid (vitamin PP/B3) and para-aminobenzoic acid (vitamin B10) to the transport through a liquid membrane of chloroform containing Aliquat 336 have been studied. The influence of operational parameters such as: solute concentration in the feed phase, stripping agent concentration in the stripping phase, transport time was monitored. The assessment of the obtained results allowed establishing of optimal transport conditions as well as identification of a kinetic transport model for nicotinic acid corresponding to consecutive irreversible 1st order reactions. The maximum transport efficiency was 96% and it was obtained at a concentration of 10-4 mol/L nicotinic acid in the feed phase and a concentration of 1 mol/L sodium hydroxide in the stripping phase. The transport time necessary to achieve this efficiency was 6 h. The results obtained led to important conclusions regarding the possibility of separating these two compounds. Analytical control of the process was done spectrophotometrically. The maximum absorbance was obtained at their characteristic wavelengths, namely 262 nm for nicotinic acid and respectively 267 nm for para-aminobenzoic acid.
The Treatment of Aluminium Pigments with Inorganic Polymers for Environment-Friendly Applications
Authors: Dragnea Draga , Gudovan Dragos , Zaharia Elena , Bildea Costin Sorin
Published: February 2020

Aluminium pigments are used in industrial and decorative coatings, automotive industry and printing inks. The encapsulation of aluminium pigments is used because the industry wants to avoid the organic solvents, for environmental reasons, by shifting towards water-borne systems. However, aluminium pigments easily react with water and a large amount of hydrogen is released leading to degradation of optical properties. This work presents experimental results concerning the encapsulation of aluminium pigments in silica matrices, by a sol-gel method using TEOS as precursor and ethylendiamine or ammonia as catalysts for the hydrolysis and condensation reactions. The samples of encapsulated pigments were characterized by gas stability tests: a boiling method and a gassing method.
Kinetics of 1-dodecanethiol Desulfurization by Reactive Adsorbtion on MgO/dolomite
Authors: Ion Constantin Sorin , Bombos Mihaela , Doukeh Rami , Vasilievici Gabriel , Matei Vasile
Published: February 2020

Desulfurisation of 1-dodecanethiol was performed by adsorption process on MgO adsorbent. The adsorbant was characterized by determining the adsorption isotherms, specific surface area, pore volume and average pore diameter. Adsorption experiments were performed in continuous system at 300-450�C, 5 atm and volume hourly space velocities of 1�2 h-1. Conversion of 1-dodecanetol increases with increasing temperature and decreasing volume hourly space velocities. It was identified the stage determinant of the process and a kinetic study of the desulfurization process was developed by reactive adsorption of 1-dodecanethiol on a magnesium oxide adsorbent.
Electrical Characterization of Titanium Dioxide Nanotubes Using Dielectric and Electrochemical Impedance Spectroscopy
Authors: Manescu (Paltanea) Veronica , Paltanea Gheorghe , Nemoianu Iosif Vasile , Popovici Dorina , Ciuceanu Radu Mircea
Published: February 2020

The paper is devoted to the electrochemical anodizing method for TiO2 nanotube layers generation on titanium surface. It is commonly accepted that parameters like anodizing time, electrical voltage and the actual type of electrolyte are important factors in what concerns the TiO2 nanotube diameters and their surface density. The present study considers self-organized titanium nanotubes resulted from an aqueous solution of 49.5 wt% H2O, 49.5 wt% glycerol, 1 wt% HF used as the electrolyte. The actual anodizing duration was 8 hours at an applied voltage of 25 V. Through the technique of scanning electron microscopy, it is shown that the resulted tubular nanostructure is one-dimensional having an approximate inner and outer diameters of 90 nm and 110 nm, respectively. From an electrical point of view, the analysed materials properties were determined using electrochemical and dielectric impedance spectroscopy tests.
The Role of Osteosynthesys Materials in the Etiopathology of Bone Malignant Tumors and Reconstruction Possibilities. Case report
Authors: Calin Cezar Ionut , Drignei Marinel , Ganatsios Stergios , Jovenet Eric , Dinache George , Savulescu Florin , Ferechide Dumitru
Published: February 2020

The use of osteosynthesis materials in orthopedics is fundamental in the surgical management of patients presenting with various pathologies of the locomotor system, in most cases trauma, but also malign and benign tumors. The risk that these materials could have in inducing malignant transformation of benign tumors or in the onset of primary malignant tumors, was rarely studied. On the one hand, primary malignant tumors of the locomotor system are much less frequent than other kind of neoplasms (for example Ewing sarcoma has an incidence of 1-3 cases / 1.000.000 people / year, ostosarcoma has an incidence of 2 cases / 1.000.000 people / year). On the other hand, usually there is a time window of several years, different from one case to another, from the moment of action of the etiopathogenic factor to the moment of revealing the presence of a neoplastic disease. Based on our clinical practice on a few clinical cases, we intend to study more thoroughly the etiology of primary bone malignant tumors in general and the role of the osteosynthesys materials in this matter especially.
The Efficiency and Degree of Penetrability of Frequent Washing Solutions Used in Endodontal Treatment
Authors: Iliescu Alexandru Andrei , Melian Anca , Dan-Cristian Ionel , Stefanescu Cristina , Anton Diana Maria , Popa Gabriela , Salceanu Mihaela , Iordache Cristina , Manole Marius
Published: February 2020

The new directions of contemporary endodontics to the evolution of treatment techniques are: CTCB, digital radiography, operating microscope, apex locators, titanium nickel rotation tools and rotating systems that allow them to be used, special endodontic irrigation means, use of ultrasonic means, laser applications. The success rate of nowadays endodontic treatments based on the principles accepted and adopted so far should be rather high. However, there are studies that indicate a fairly low percentage of fully successful endodontic treatments. The main causes for which these data are recorded are various, some are strictly the dentist�s technique and some are related to the patient�s field. Obviously, there is a contradiction between what can be achieved and the final result. The study includes a batch of 52 teeth pluriradicular as well as monoradiculars considered irrecoverable and extracted due to clinical situations requiring this method of treatment. Anatomy of dental canals is an important factor to be considered in the irrigation efficiency of the apical region; the degree of permeability of dentinal canals in this area is poor due to very small diameters, cumulative factors can lead for sure to a failure of endodontic treatment. In the coronal and media regions of the channels, the effectiveness of the lavage solutions used could be assessed. These very good results were in accordance with the studies performed and presented.
Optimised Pu-erh Tea Infusion by Experimental Design and Response Surface Methodology
Authors: Isopescu Raluca Daniela , Josceanu Ana Maria , Minca Iulian Ilie , Isopencu Gabriela
Published: February 2020

Apart from the green and black tea consumption, post-fermented Pu-erh specialties are increasingly present even on emerging markets as the one in Romania. Despite simplicity, infusion preparation should be conducted so that polyphenols content reaches its peak, and toxic elements (heavy metals, nitrates) are eliminated or limited to their maximum admitted levels for foodstuff. The study was carried out based on a central composite design, infusion composition being used for proposing regression models representing the response surface generated by the measured parameters as function of working conditions. The analyzed factors were contact time, temperature, and stirring rate. Multi-objective optimization signaled series of operational parameters values yielding maximum polyphenols, at minimum cadmium and nitrate contents in Pu-erh tea infusions. Typically, infusions prepared at 82 - 83�C, using 6 min contact time, and 170 rpm contain 8.9 % polyphenols, while cadmium reaches 3.98 mg/mL, and nitrate 0.35 mg/mL.
Renal Impairment in Young Patients with Unilateral Ureteral Lithiasis Obstruction: What Factors can be Responsible?
Authors: Pricop Catalin , Vacaroiu Ileana Adela , Radulescu Daniela , Andone Daniel , Puia Dragos
Published: February 2020

In the literature, occurrence of acute kidney injury (AKI) in young patients with unilateral ureteral lithiasic obstruction and without previous renal impairment is not very often reported, and the underlined pathophysiological mechanisms are poorly known; according to some studies, it is a false kidney failure, the increase in serum creatinine being due to absorbtion of obstructed urine in the affected kidney. We have conducted a retro and prospective study in order to identify the possible risk factors that can cause renal function impairment in young patients (18-40 years) with unilateral ureteral lithiasis obstruction and a normal contralateral kidney. Results. From 402 patients included in the study, 20.64% (83 cases) presented with serum creatinine ] 1.3 mg/dL. In patients with renal impairment, prevalence of male gender and history of NSAIDS use before admission were significantly higher than in non-AKI group. Serum urea/creatinine ratio, and estimated glomerular filtration rate (MDRD formula) were significantly higher, and respectively lower in AKI group. We found no significant differences between the two groups regarding age, prevalence of urinary tract infection after relief of obstruction, C-reactive protein value, and the duration of hospitalization. Conclusions. AKI in young patients with unilateral ureteral lithiasis obstruction and normal contralateral kidney is not quite a rare finding in our region. NSAIDs use can influence development of AKI, and should be used cautiously even in young patients with renal colic. In our opinion, the presence of AKI in patients with unilateral hydronephrosis demands urgent endourological intervention. Choosing conservative therapy in these patients, especially treatment with NSAIDS may aggravate the renal dysfunction.
Oxymercuration-demercuration of(�)-(1alfa,3 alfa,3a beta,6a beta)-1,2,3,3a,4,6a-hexahydro-1,3-pentalenedimethanol Dibenzoate
Authors: Tanase Constantin I. , Draghici Constantin , Pintilie Lucia , Negut Catalina
Published: February 2020

Oxymercuration of (�)-(1a,3a,3ab,6ab)-1,2,3,3a,4,6a-hexahydro-1,3-pentalenedimethanol dibenzoate 1 was performed with mercuric tetrafluoroborate alone, in the presence of tetrafluoroboric acid and with tetrafluoroboric acid + sodium acetate and demercuration with sodium borohydride in 3N NaOH. The hydration of the alkene was selective toward the symmetric alcohol at short time, but at prolonged time, the symmetric and un-symmetric alcohols were obtained in a near 1:1 ratio. Anyway, the oxymercuration-demercuration of alkene 1 is a slow hydration reaction.
Relationships Between Microstructure, Roughness Parameters and Ultrasonic Cavitation Erosion Behaviour of Nodular Cast Iron, EN-GJS-400-15
Authors: Mitelea Ion , Bena Traian , Bordeasu Ilare , Craciunescu Corneliu Marius
Published: February 2020

The main objective of this paper is to investigate the influence of microstructure on the degradation of nodular casting by cavitation erosion and the correlation of the surface wear parameters with the sizes that characterize the resistance opposite to the cavitation phenomenon. The cavitation tests were conducted on a vibrator with piezoceramic crystals, respecting the ASTM G32-2010 standard. Microstructural investigations on eroded surfaces were performed on the optical microscope and the scanning electron microscope, and the roughness measurements with the Mitutoyo apparatus. The obtained results have demonstrated the existence of a good correlation between the resistance to cavitation erosion and the roughness parameters Ra, Rz and Rt.
Correlations Between Inflammatory Biomarkers and Activity in Inflammatory Bowel Diseases
Authors: Mihai Catalina , Cijevschi Prelipcean Cristina , Dranga Mihaela , Gavrilescu Otilia , Cardoneanu Anca , Lacatusu Cristina , Mihai Bogdan Mircea
Published: February 2020

There is an increasing interest in non-invasive methods to assess gut inflammation. The data regarding the correlations between inflammatory markers and activity of inflammatory bowel disease (IBD) are still controversial. In the last years faecal calprotectin became the most widely used biomarker in diagnosis and monitoring the IBD activity. We prospectively studied the correlation between the serological inflammatory markers (platelets, erythrocyte sedimentation rate - ESR, fibrinogen, C Reactive Protein -CRP, ferritin, albumin), faecal calprotectin and severity of IBD in a tertiary referral centre in North-East Romania. Our study demonstrated that is a good correlation between serologic inflammatory markers (platelets, fibrinogen and ferritin, not ESR and albumin) and severity of IBD. CRP is a good marker in Crohn�s disease (CD) but not in ulcerative colitis (UC). Faecal calprotectin (FC) is the best inflammatory biomarker which correlates with activity both in UC and CD. Inflammatory biomarkers, especially FC are an important tool to evaluate patients with IBD.