bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of naringin on the electrophysiology of mouse ventricular myocytes and its anti-arrhythmic effect
Authors: Li Shihan , Ma Guolan , Zhang Shuangling , Cao Zhenzhen , Zhang Peihua
Published: November 2022

Naringin is a flavonoid extracted from citrus plants which have a
variety of biological activities. Studies have shown that eating more
food rich in flavonoids can reduce the incidence of cardiac arrhythmia.
Naringin has been reported to have beneficial cardiovascular effects but
its electrophysiological mechanism against arrhythmia has not been
elucidated. Here, we used the whole-cell patch-clamp technique and
BL-420F biological signal acquisition and analysis system to record the
APs, ionic currents, and Electrocardiogram (ECG). At the cellular level,
naringin prolonged the APD of ventricular myocytes and decreased the
Vmax of APs. Naringin inhibited L-type calcium current (ICa.L), peak
sodium current (INa.P), delayed rectifier potassium current (IK),
transient outward potassium current (Ito), and ATX II enhanced late
sodium current (INa.L) in a concentration-dependent manner. Moreover,
naringin reduced CaCl2-induced DADs and ATX II-induced APD prolongation
and EADs. At the organ level, naringin reduced the incidence of VT and
VF induced by ATX II and prolonged the onset time of both in mouse
hearts. For the first time, the electrophysiological method was applied
to elucidate that naringin may be a multi-channel blocker with
antiarrhythmic effects.
Corollary discharge function in healthy controls: new evidence about self-speech and external speech processing.
Authors: Sierra Rosa María Beño Ruiz de la , Arjona Antonio , Estevez Sabela Fondevila , Fernández-Linsenbarth Inés , Diez Alvaro , Molina Vicente
Published: November 2022

As we speak, corollary discharge mechanisms suppress the auditory
cortical response to the sensory perception of the self-generated voice
in healthy subjects. This suppression has been associated with the
attenuation of the auditory N1 component. To analyze this corollary
discharge phenomenon (agency and ownership), we registered the
Event-Related Potentials (ERPs) of thirty-five healthy subjects. The N1
and P2 components were elicited by spoken vowels (talk condition;
agency), by played-back vowels recorded with their own voice
(listen-self condition; ownership), and by played-back vowels recorded
with an external voice (listen-other condition). The N1 amplitude
elicited by the talk condition was smaller compared to the listen-self
and listen-other conditions. There were no amplitude differences in N1
between listen-self and listen-other conditions. The P2 component did
not show differences between conditions. Additionally, a peak latency
analysis of N1 and P2 components between the three conditions showed no
differences. These findings corroborate previous results showing that
the corollary discharge mechanisms dampen sensory responses to
self-generated speech (agency experience), and also provide new
neurophysiological evidence about the similarities in the processing of
played-back vowels with our own voice (ownership experience) and with an
external voice.
Why I left and why I want to leave; A Phenomenological Perspective of Asian Employees Turnover
Authors: Kazi Metab Abbass , Anwer Naveed , Lakho Jahngeer , Kazi Abbass
Published: November 2022

The current research was conducted to explore the possible causes of actual employee turnover and turnover intentions. Using Post positivism research philosophy, phenomenological qualitative research method was used to explore the phenomena. Semi-structured interviews of 21 bank employees (selected using purposive sampling) were conducted which were analyzed using NVivo 12. The research findings suggest many uniques themes in order to overcome the problem of employee turnover, especially for banks. The themes which were developed consisted of five significant themes such as the bank appraisals and reward system was identified as biased and based more on favoritism, employee feel that their actual performance is not evaluated properly and sincerely. The other factor concluded by the research findings is that the employees are dissatisfied with the salary and benefits, as they felt that there should a consistent effort to identify employee personal needs which should be customized accordingly in their compensation plans as well. The very essential factor recognized in the research finding was the upward and downward communication gaps with the employees. Such perceptions generated related issues as the employees felt that branches are much deprived to have a direct communication channel with the top team heads. The other very essential factor discovered after the investigation of the phenomena of turnover is lack of career growth. Lastly, another important cause of employee turnover was the transfers, which took place without the consent of the employee. Employees felt demotivated due to such transfers and changes in their work locations. Recommendations and future research directions have been at the end of the research
percepção docente sobre o material didático digital em plataforma de educação on-line
Authors: Oliveira Cardoso Gilson , Martins Giraffa Lucia Maria
Published: November 2022

Este artigo apresenta os resultados de uma pesquisa embasada por uma abordagem fenomenológica, desenvolvida por meio de abordagem qualitativa/exploratória e apoiada em um estudo de caso em escola confessional de Educação Básica da cidade de Porto Alegre, onde investigamos as restrições e dificuldades percebidas pelos professores que utilizam material didático digital, quanto à sua integração em uma plataforma on-line, a fim de que esta seja considerada por eles fonte primária (preferencial) para a organização do processo de ensinar. Os dados foram observados a partir da análise textual discursiva (ATD) proposta por Moraes e Galiazzi. As reflexões produzidas nos fizeram compreender que as restrições e dificuldades percebidas pelos professores da escola estão relacionadas aos aspectos da estruturação dos recursos da plataforma e sua organização, os quais impactam na organização metodológica dos docentes. Outro aspecto emergente diz respeito à formação continuada dos professores, referindo-se às funcionalidades e atualizações da plataforma e à integração de materiais oriundos de outras fontes digitaisque sejam dos professores ou sugestões dos estudantes.
Developing the Sustainable Bond Market in ASEAN+3: Challenges and Opportunities
Authors:   Asian Development Bank, Puongsopol Kosintr , Tian Shu ,   Asian Development Bank, Yamadera Satoru ,   Asian Development Bank
Published: November 2022

This brief highlights the potential for developing sustainable bond markets in the ASEAN+3 region and suggests ways forward. It notes that renewable energy and energy efficiency are seen as promising sectors for the development of green bonds. It suggests how policymakers and development partners can help expand the issuer base and increase local demand for sustainable bonds, increase project bankability, and create an enabling ecosystem.
The effectiveness of PCR-RT method for etiological diagnosis of atypical forms of whooping cough
Authors: Medkova A. Yu. , Syomin E. G. , Sinyashina L. N. , Babachenko I. V. , Karataev G. I.
Published: November 2022

The aim of the study was to evaluate the effectiveness of the PCR-RТ method using the PCR-RТ-IS test system for the etiological diagnosis of whooping cough in the examination of patients with infectious respiratory pathology with prolonged cough and in contact persons. 113 children aged from 1 month to 17 years, 11 months and 29 days, and 146 contact family members were examined. Regardless of the initial diagnosis, all children were examined for whooping cough by bacteriological, molecular genetic and serological methods. For molecular genetic diagnostics a commercial kit and PCR-RT-IS test-system developed at the Gamaleya Research Center were used. The contact persons were examined by the bacteriological method and using the PCR-RT-IS test-system. During the initial examination the diagnoses «Acute respiratory viral infectious», «Acute rhinopharyngitis», «Acute laryngotracheitis», «Acute bronchitis», «Pneumonia» were established. The severity of cough in contact persons was different – from a typical spastic «whooping cough» to complete absence of cough. By using the PCR-RT-IS test-system we developed, the DNA of pertussis pathogen was detected in groups of patients with «Acute rhinopharyngitis» in 34.4% of cases, «Acute laryngotracheitis» – in 64.3%, «Acute bronchitis» – in 69%, with a diagnosis of «Pneumonia» – in 33.3% of cases. In a number of cases combined course of whooping cough with respiratory infections (respiratory syncytial virus, rhinovirus and others) was detected. In the examined contact persons the causative agent of pertussis was detected using the PCR-RT-IS test-system in 51,4% of cases.
Autochthonous visceral leishmaniasis in the Russian Federation and the role of polymerase chain reaction as an alternative diagnostic method
Authors: Lebedeva T. M. , Chuelov S. B. , Sayfullin М. А. , Rossina A. L. , Zvereva N. N. , Pylaeva E. Y. , Volkova G. I. , Ivanova Yu. N. , Kryukova L. V. , Litsev A. A. , Karan L. S.
Published: November 2022

The aim of the work is to summarize the available literature data on cases of visceral leishmaniasis in children registered in the Russian Federation, as well as to describe our own clinical observation of autochthonous visceral leishmaniasis in a 9-year-old child, in the diagnosis of which the polymerase chain reaction (PCR) method was used.

Materials and methods: a review of domestic and foreign literature over the past 20 years, including Internet resources, was carried out. We observed a 9-year-old child hospitalized in the Russian Children's Clinical Hospital. Leishmania DNA was determined in blood serum by PCR using the Amplisens – Leishmania-Fl reagent kit.

Results. It was established that the infection of the patient observed by us occurred on the territory of the Russian Federation in the Crimea. The diagnosis of leishmaniasis was confirmed by morphological examination of the bone marrow and the detection of pathogen DNA in the blood serum by PCR.

Conclusion. On the territory of the Russian Federation there are foci of autochthonous visceral leishmaniasis in the Crimea and the North Caucasus. Polymerase chain reaction is an alternative to bone marrow aspirate microscopy for the diagnosis of visceral leishmaniasis.
The epidemiological situation of coronavirus infection (COVID-19) in the Republic of Dagestan and measures to reduce it
Authors: Ulukhanova L. U. , Karnaeva N. S. , Dzhabrailova M. E. , Agaeva S. G. , Gadzhimirzaeva A. G.
Published: November 2022

The article shows the epidemiological situation of the coronavirus infection COVID-19 (SARS-CoV2) in the Republic of Dagestan for the period 2020-2022, according to the «Republican Center for Infectious Diseases and AIDS» of Makhachkala, Dagestan. Results. The epidemiological situation of the new coronavirus infection in the Republic of Dagestan (RD) remains unfavorable. In 2020, since the beginning of the pandemic, the «Wuhan» strain has been circulating, and since September 2020, the active circulation of the British «alpha» strain has begun. A new wave in 2021 with the highest incidence was recorded from June to September – associated with the inclusion of the Indian «delta» strain SARS-CoV-2 in the epidemic process. Strains of «omicron» that exist today are BA.1 and BA.2 may lead to hospitalization. They are still dangerous for residential people and patients with risk factors. Conclusion. Among the adult population, the largest number of cases of the disease was registered 90.7%. Three main age risk groups have been identified: the adult population from 50 to 64 years; from 65 years and older and from 40 to 49 years. The analysis of mortality by age groups also revealed the main risk groups: persons aged 50-59 years (15.12%); 60-64 years (23%) and over 65 years (55.6%). On 04.07.2022 1,557,661 people were vaccinated with the Gum-COVID-Vac, EpiVacCorona, KoviVak and Sputnik Light vaccine, including 1,377,645 people who completed vaccination.
Clinical and etiological characteristics of mixed infections in children in the Izhevsk hospital
Authors: Britkova T. A. , Panteleev K. E. , Pazinenko O. A.
Published: November 2022

Aim: to study the structure, features of the findings and treatment of mixed infections in children at the present stage.

Materials and methods. 85 case histories of children aged 5 months to 17 years and 10 months were examined, the final diagnosis of which included 2 or more infections on the basis of the children's infectious diseases department City Clinical Hospital № 7 of Izhevsk. Children with acute infectious pathology (acute intestinal infections, acute respiratory infections, herpes infections) are hospitalized in this hospital. Diagnostic methods: polymerase chain reaction, ELISA, bacteriological.

Results. Mixed infections are equally common in both boys and girls, while there is a predominance of mixed infections in young children (up to 1 year and from 1 year to 3 years) 62.4%. The structure of infectious morbidity is consistently dominated by acute enteric infection – 83.5% cases and acute respiratory infections – 53.0% cases. The progression of SARS-CoV-2-associated and herpes-associated mixed infections is characterized by a pronounced polymorphism of clinical manifestations. The etiological factor for each nosology was deciphered only in 17.7%; in 43.5% of cases, only one etiological factor was verified in the laboratory; in 38.8% of cases, no etiological factor was confirmed in the laboratory.
Features of the course of COVID-19 in combination with respiratory mycoplasmosis in children
Authors: Dracheva N. A. , Mazankova L. N. , Samitova E. R. , Osmanov I. M. , Klimova O. I. , Demina O. I.
Published: November 2022

During the COVID-19 pandemic, the combination of infections caused by SARS-Cov-2 and M. rheimopiae is the subject of increased attention of clinicians. This article presents an observation of 37 children with COVID-19 in combination with respiratory mycoplasmosis (RM), the purpose of which was to identify the features of the course of combined infections compared with monoinfections. According to the results of the study, the similarity of the clinical picture of upper and lower respiratory tract lesions in the groups of combined infections and monoinfection COVID-19 was reliably established, which requires updating the examination and treatment plan in the study cohort of children.
The centenary jubilee of the discovery of prehistoric striped flint mines in Krzemionki
Authors: Przychodni Andrzej , Jedynak Artur
Published: November 2022

Undoubtedly, the exploitation field in Krzemionki, situated within the properties of the present villages of Sudół, Stoki Stare and Ruda Kościelna, constitutes a unique relic – the monument of prehistory whose preservation in as good state as possible accompanied with skilful facilitating it to the public is going to be the subject of our concern throughout the upcoming century. From one hand, one could be surprised that the monument did not become a symbol equally recognizable to the Biskupin fortified town. On the other, it should be admitted with delight that the whole range of activities completed regarding the monument have not caused any significant alterations to the object as specified. They might possibly occur along with vaster popularization and commercialization of Krzemionki mines. Of course, some interference took place here indeed. However, luckily their scale have not caused loss which we could reckon as considerable, taking into account the number of intact mining shafts or post-mining landscape, visible until today at substantial stretch of the field. It seems that in the case of this archaeological monument a successful compromise was obtained. It merges a strive for retaining as little changed state as possible, getting knowledge in the course of research and finally the need for the knowledge and the object as it is to be presented. If we manage to keep the situation like that it will be possible to claim that intergenerational actions of various environments in the service of Krzemionki monument led to proper effects.
Tinbergen on the Theory and Policy of Economic Development
Authors: Boianovsky Mauro
Published: November 2022

As part of a book symposium on Erwin Dekker's Jan Tinbergen (1903–1994) and the Rise of Economic Expertise (2021), Mauro Boianovsky reflects on Tinbergen's 'uniqueness' among development economists in the post-war era.
Асимптотична поведінка розв'язків лінійних диференціальних рівнянь загального вигляду збурених за допомогою вінерівського процесу
Authors: Десницький О. М. , Млавець Ю. Ю. , Орловський І. В. , Тимошенко О. А.
Published: November 2022

У роботі доведено граничну теорему про асимптотичну поведінку розв'язків лінійних стохастичних диференціальних рівняння. Рівняння цього типу є узагальненням багатьох моделей, що широко використовуються у задачах фінансової математики. Доведення базується на застосуванні техніки розробленої в роботах Й. І. Гіхмана та А. В. Скорохода для автономних стохастичних диференціальних рівнянь. Знайдено умови, за яких асимптотична поведінка розв'язку лінійного стохастичного диференціального рівняння визначається невипадковою функцією. Наведено приклади симуляцій за допомогою метода Ейлера-Маруями.
TELAAH FILOSOFIS ATAS ARSITEKTUR DIGITAL Kasus Studi Arsitektur Digital Neo-Nusantara di Ibu Kota Negara (IKN)
Authors: Soesilo Rudyanto
Published: November 2022

All aspects of life cannot escape the development of the times with the last phenomenon being the influence of the development of the digital world which is called the process of "digitalization". Architecture as one aspect of life certainly does not escape undergoing this digitilization process. Aim this paper discusses the process of digitalizing architecture using a philosophical point of view. The research was conducted using Desk research, from data and existing literature. The data is then filtered according to its interrelationships, validity and adjusted to its needs. Then a predictive analysis was carried out to get a (hypothetical) conception of digital architecture digital architecture in IKN Nusantara. The results of this discussion are understanding of the application of the digital ontological paradigm into the architectural process carried out at IKN Nusantara as a study case and in the context of the creative economy, which is the future of the Indonesian Economy,  is very appropriate to develop a Neo-vernacular Digital Architecture in Indonesia which is hereinafter referred to as Neo-Nusantara Architecture.
Assessment of Medication Adherence among Diabetic and Hypertensive Patients Visiting an Urban Health Centre Affiliated with a Tertiary Care Hospital during Lockdown Imposed due to COVID-19 Pandemic
Authors:   Public Health Nursing Officer, Department of Community Medicine, VMMC & Safdarjung Hospital, New Delhi, India, Mishra Alka
Published: November 2022

Introduction: COVID-19 is a major health crisis, which led to a nationwide lockdown. The combined effect of the COVID-19 pandemic and lockdown impacted patients suffering from non-communicable diseases. Aims: To assess medication compliance among diabetic and hypertensive patients during lockdown due to COVID-19 and to find out the association between factors affecting compliance during lockdown due to COVID-19. Method: All patients registered at an urban health training centre for treatment of diabetes, hypertension or both. The study was a facility-based cross-sectional study, done at an Urban Health Training Centre (UHTC), affiliated with VMMC & Safdarjung Hospital, New Delhi. 145 patients were taking treatment for diabetes mellitus, hypertension, or both for six months or more, at UHTC before the commencement of lockdown. Data were collected using a structured questionnaire. Patients were contacted telephonically. Data were analysed for frequency and percentage, and the relationship was assessed using chi-square test/ Fisher’s exact test. Results: Majority of participants were male (51%) and had BMI in the range of normal to overweight (44% and 43.1% respectively). Loss of job was reported by 73% of participants and majority of participants were earning INR 6001 to 10000 before lockdown. The main reason for noncompliance was financial. Sex, migration, and source of medication were significantly related to medication compliance. Conclusions: Though most patients were compliant, the main reason for non-compliance was financial and related to migration.
Management and Treatment of Gastritis (War’m-e-Meda) with Herbal Remedies: An Overview
Authors:   PG Scholar, Department of Tahaffuzi Wa Samaji Tib, Faculty of Unani Medicine, AMU, Aligarh, Uttar Pradesh, India, Mazhar Syeda Ayeman
Published: November 2022

Stomach complaints are still a common health problem. Among them, gastritis affects 25-33% of the total population of India, of which most of them belong to the age group of 15-50 years. There are two types of gastritis - acute and chronic. Acute gastritis is a mucosal inflammatory process that may be asymptomatic. Chronic gastritis is one of the most common serious epidemic infections, e.g. peptic ulcer or gastric ulcer. In the Unani system of medicine, gastritis is also known by many names: Hurqat-e-Meda, Sozish-e-Meda, Warm-e-Meda, and Ilttehab-e-Meda. Gastritis is most commonly caused due to metabolic stress, drug intake, and corrosive injuries. Other factors such as tobacco consumption, psychosocial stress, and nutritional factors also play an important role in its occurrence. We will discuss in detail the efficacy of some Unani herbal drugs in acute and chronic gastritis.
Unani Concept of Fasd (Venesection): A Review
Authors:   PG Scholar, Department of Tahaffuzi Wa Samaji Tib, Faculty of Unani Medicine, AMU, Aligarh, Uttar Pradesh, India, Mazhar Syeda Ayeman
Published: November 2022

Unani medicine is an assortment of opinions, views, and concepts of the Greek and Arab scholars and is often termed as Greco-Arabmedicine. It is a traditional method of treatment, established on the concepts of renowned physician-philosopher Buqrat (Hippocrates) followed by Avicenna, Rhazes, Averroes and so on. Four modalities of treatment are described, of which Ilāj bit Tadbīr (regimental therapy) is one among them. Ilāj bit Tadbīr comprises different types of regimes for the accomplishment of health and disease-free life. Taleeq, Dalk, Fasd, Hijamah, Hamman etc. are various common regimes practised all over the world predominantly in the Middle East. Ilāj bit Tadbīrencompasses regimes that try to correct this disruption and help the body to restore itself. According to the Unani philosophy, every individual has a distinctive humoral constitution; health is attained when there is balance in the humors, and any imbalance leads to a disease condition. Faşd (venesection) is a part of Ilāj bit Tadbīr which involves blood-letting by placing an incision in specified veins. It is mentioned as a minor procedure meant for excretion of morbid matter which has both preventive and therapeutic benefits. Faşd has manifold benefits including istifrāgh (excretion) of wastes, removal of imtila (plethora), and reduction in viscosity of blood. Hence, if carried out according to guidelines, it serves as an effective treatment modality in many local and systemic disorders. The present paper aims at reviewing the literature to intricately discuss Fasd with special mention to Unani medicine.
Fuzzification of Intelligence Quotient (IQ) for the Determination of Individual Temperament (Mizaj-e-Shakhsi)
Authors:   Assistant Professor, Department of Tashreeh wa Munafeul aza, Ajmal Khan Tibbia College, AMU, Aligarh, Aijaz Aisha
Published: November 2022

Introduction: Temperament assessment is the key point on which whole of the Unani therapeutics depends. The various methods mentioned in classical Unani manuscripts are observation based liable to mistakes. Therefore, there is a need of searching some scientific methods of temperament assessment not the mere subjective parameters and that can be employed universally. Keeping this aim in mind this work was done in the department of Tashreeh wa Munafeul Aza, AKTC, AMU. Method: The author has submitted a thesis in which the IQ was established as a tool for assessment of individual temperament using Boolean logic. Then taking those data, fuzzy logic was applied and fuzzification of IQ levels was done. The results thus obtained were compared. Result: The assessment of individual temperament using Boolean Logic applied to IQ levels the individuals can be identified as Hot and Cold temperament persons. While applying fuzzy logic the subjects were identified as haar, baarid anf motadil temperament with specifications of degrees of temperaments. Conclusion: Fuzzification is the better method of assessment of individual temperament.
A Study to Assess the Impact of Modified Early Ambulation on Functional Activity among Patients after Abdominal Surgery in a Selected Hospital of Kashmir
Authors:   Nursing Officer, SKIMS Soura, Srinagar, Jammu & Kashmir, India, Jahan Mustaqeem
Published: November 2022

Background: Lack of early ambulation after abdominal surgery is the main cause of morbidity and mortality in India and all over the world. Many types of research have been done to prove that early ambulation improves postoperative recovery, reduces the incidence of postoperative complications and promotes early discharge. Modified early ambulation is a non-pharmacological method of postoperative management and has the advantage of being cost-effective, easy to provide, and safe. Methodology: A quasi-experimental post-test-only control group design was adopted for the study. The study was carried out on 50 abdominal surgery patients (25 in the experimental group and 25 in the control group) who were admitted to the surgical wards of the Sher-i-Kashmir Institute of Medical Sciences, Soura Kashmir. Results: The findings of the study revealed that there was a significant (p=0.05) increase in scores of functional activity of patients in the experimental group than in the control group. At 40 hours, 64 hours and 88 hours, the (Mean ± SD) functional activity scores of experimental group were (5.76 ± 1.508, 2.12 ± 0.927, 8.16 ± 0.624) and control group (5.80 ± 2.121, 8.80 ± 0.500 and 8.16 ± 1.248) with the p-value of 0.00, 0.00 and 0.0213 respectively. There was statistically no significant association between functional activity among patients after abdominal surgery in control group with any of the demographic and clinical variables i.e., age (p = 0.065), Gender (p = 0.132), Pre hospitalization levels of activity (p = 0.588), Previous abdominal surgery (p = 0.692), Previous knowledge about postoperative ambulation (p = 0.692) and Comorbidity (p = 0.238). Conclusion: Based on the present study it can be concluded that the modified early ambulation intervention in the study group had a significant effect on the functional activity of study subjects.
The Efficacy of Yoga Practice during Pregnancy on Postnatal Depression & Quality of Life
Authors:   Associate Professor, Division of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana (SVYASA) deemed to be University, Bengaluru, India, Maharana Satyapriya
Published: November 2022

Background:The postpartum period is a very special phase in the life of a woman and her newborn.There was high prevalence of depression during postnatal phase. Previous studies proposed that yoga practice has found health benefited effects in pregnancy & postnatal phase. Aim:To study the effect of yoga practice during pregnancy on postnatal depression & quality of life. Methodology: A cross-section study on sixty-eight pregnant women with mean age ranging from 20 to 35 years with mean age of (29.66 ± 3.57) were enrolled in this study. They were divided into groups (yoga n=37) & control (31). Subjects with known case of Pregnancy complications, labor complications, psychiatric illness & medical illness were excluded from the study. The subjects of yoga group were attended four month of yoga practice consist of asana, pranayama, & relaxation techniques thrice in week for one hour per session per day during their pregnancy. And the subjects of control group followed their daily routine with walking for one hour. Quality of life & EPDS were assessed. The assessments were carried out after 10th week of postnatal period. Mann-Whitney test was used to assess between group differences. Result: Quality of life measured by QOL more in yoga group: Physical Health (P<0.001), Psychological health (P<0.003), Social relationship (P<0.001), Environmental health (P<0.016) than control group. Postnatal depression as measured by EPDS less in yoga than control (P<0.001) with significant difference between groups. In yoga group, Out of 37 participants ten pregnant women (27 %) have score 10 & above (EPDS) score suggesting clinically depression, where as in control group, out of 31 participants fifteen pregnant (48%) women have score more than ten & above (EPDS). Conclusion: Practice of yoga during pregnancy may help in reducing postnatal depression & improves quality of life in postnatal period.
Clinical Management of Accidental Python Bite
Authors:   MD, DTM & HM Aviation Medicine, Medical Director, Bangkok, Thailand, Premmanisakul Sumait
Published: November 2022

We present here a case report regarding a patient, who sustained a severe hand injury following an accidental python bite. Python-bite injuries are rare and there are no definite guidelines in the literature regarding the management of python-bite injuries. This report details our experience in clinically managing this case, one of the few in the literature. On March 18, 2022, a 20-year male was accidentally bitten by a reticulated python while trying to rescue the snake from the middle of a road. The python was 3.5 meters in length. The bite was on the right knuckle area of the right hand. There was strong bleeding that slowed down after a few minutes. An hour later, the patient could reach the nearby hospital where the wound was thoroughly cleaned with soap and water and antiseptics were given. Broad-spectrum antibiotics were given along with TT and pain killers. Wounds were left open but thorough wound cleaning with betadine was done at the site of teeth marks. Wound cleaning and sterile dressings were applied daily. Despite this, after 3 days there was swelling of the hand as infection had set in. More antiseptics were added IM and topically. After 5 days, there was mild relief in swelling and infection. The patient was fine after a follow-up of 2 weeks with mild swelling.
Agranulocytosis - A Rare Side Effect of Standard Dose Ceftriaxone Therapy
Authors:   MD Pathology, Excel Diagnostics, Lucknow, Uttar Pradesh, India, Singh Priya
Published: November 2022

In the current era of medical science, agranulocytosis is rarely found. Chemotherapeutic agents and various non-chemotherapeutic drugs commonly cause agranulocytosis. Agranulocytosis can occur any time during the therapy in hospital, and patients may remain symptomless. So, we should do regular cell count to reach the diagnosis in such cases. An appropriate antibiotic or drug-change, investigations to rule out sepsis and granulocyte colony-stimulating factor (G-CSF) injection can be given as the management part. The patient should be monitored daily and observed till the normalization of neutrophil counts. Here, we report a case of ceftriaxone-mediated agranulocytosis, which was completely reversible after withdrawing the antibiotic.
Interactive Large-group Newborn Health Learning Experiences among Students of Homeopathy
Authors:   MD, Associate Professor, Department of Paediatrics, Maulana Azad Medical Sciences, New Delhi, India, Dabas Aashima
Published: November 2022

Background: Flipped classroom is an interactive teaching-learning method which has reported good acceptability in medical education. The effectiveness of this technique in teaching a non-mainstream subject is less explored. Objective: This study was planned to assess the understanding among the homoeopathic students of a clinical subject taught via flipped class methodology. Method: The flipped classroom approach was used for conducting online teaching sessions in paediatrics for the undergraduate students of homoeopathy. The students were provided with lecture material and learning aids before each of the two sessions on newborn health. Two separate online sessions were conducted in flipped class style. Students were asked to respond to a post-test questionnaire for knowledge assessment and a feedback questionnaire regarding learning satisfaction. A five-point Likert scale was used to assess the satisfaction experiences. Results: A total of 64 responses were received after both classes where the mean (SD) knowledge score was 6.3 (1.2). Majority (79.6%) did not find the preparation for the lecture to be difficult and 63 (98.4%) agreed that this lecture style is helpful for learning. 53 (82.8%) participants agreed that it is useful for the preparation of examinations. Majority (90.6%) rated the satisfaction after the class as 4 or 5. Few topics were suggested for further learning by the students after the class. Conclusion: Flipped classroom was used as a novel approach for teaching a clinical subject to the students of homoeopathy. High student satisfaction in terms of learning motivation and usefulness in preparation for examinations was recorded.
Dehiscence of Uterine Hysteroraphy After Caesarian Section Associated with Secondary Anemia, Subaponevrotic Hematoma or Dehiscence of Skin Wound
Authors: Ana-Maria Brezeanu , Dragos-Marian Brezeanu , Vlad-Iustin Tica
Published: November 2022

Introduction: The incidence of cesarean section has increased significantly in recent years. The study is retrospective and observational, over a period of 5 years (From April 2017 to April 2022). The present paper aims to show the correlation between the dehiscence of the hysteroraphic tranche, with anemia, the postoperative hematoma or the dehiscence of the skin wound in the postoperative period.

Working method: This study was performed on a group of 5562 patients who gave birth by caesarean section, and found 4 patients who met the inclusion criteria. The inclusion criteria were secondary anemia, subaponevrotic haematoma or cutaneous wound dehiscence, associated with uterine dehiscence, followed by hysterectomy.

Results: Patients with uterine wound dehiscence had subaponevrotic hematoma in all cases (100%) and only one patient had an association between a supraaponevrotic hematoma and a subaponevrotic hematoma (11%).

From the perspective of cutaneous wound dehiscence, of the nine patients included in the study, only one patient (11%) presented wound dehiscence after hysterectomy. This patient did not need suturing of the wound, being treated conservatively.

Conclusions: Out of the studied group of 5562 patients, 16 patients developed subaponevrotic haematomas, 4 of them developing uterine histeroraphy dehiscence and requiring a hysterectomy, with an incidence of 25%.
Aspects of Epidemiology and Treatment of Supracondylar Fractures of the Humerus in Children in South-Eastern Romania
Authors: Alexandru Valcu , Iulian Manac , Bogdan Obada
Published: November 2022

Supracondylar fractures are frequently encountered in childre and have a high prevalence of associated complications. Supracondylar fractures, due to their frequency, aspect and the serious health problems that can result, require a rapid and precise intervention, based on a well-defined evaluation methodology

In this paper, we assess the epidemiology and the management of supracondylar fractures treated within the Surgery and Pediatric Orthopedics Clinic of the Emergency County Hospital of Constanta.

We conducted a retrospective study on 222 pediatric patients with supracondylar fractures of the humerus during between 2019 and 2021 treated in County Clinical Emergency Hospital of Constanta. The data was collected from the medical records of the patients recorded on the Clinic of Pediatric Surgery and Pediatric Orthopedics.

We obtained a higher percentage of males with fractures (60%). Falling from the same level was the main cause of fracture, followed at close distance by fall from different level, other causes, among which car accidents being observed less in our study.
Architectural Features of Cities and Towns during the Period of Lithuania’s Reconstruction in 1918–1925
Authors: Tranavičiūtė Brigita , Petrulis Vaidas , Laurinaitis Paulius Tautvydas , Pakštalis Arvydas
Published: November 2022

The purpose of this research is to disclose the architectural features of cities and towns during the period of Lithuania’s reconstruction in 1918–1925. Therefore, the features are analysed according to three criteria – the functional needs of a newly founded state, its technical capacities and stylistic preferences – by granting an acceptable stylistic shape to buildings. The results of this will help to identify the state’s functional needs in consideration of losses caused by WWI to a country that could not be reconstructed in full from the then state budget; thus, from the very beginning the focus was on reconstruction of public buildings and residential houses, out of necessity.
The acoustic communication of the Eurasian Green Woodpecker (Picus viridis)
Authors: Turner Kyle , Gorman Gerard , Alder Danny
Published: November 2022

Woodpeckers, having a fairly well-defined range of acoustic signals, offer a valuable opportunity to link acoustic repertoires to behavioural observations. Instrumental and vocal sounds from more than 70 individual Eurasian Green Woodpeckers were analysed using 305 sound recordings. Eighteen separate acoustic signals are described, together with field observations of associated behaviour. Sixteen are illustrated by clear spectrograms supporting the phonetic descriptions. With one exception, calls consisted of repeated elements, with the first element often containing varying degrees of emphasis. Variation within call types, especially the advertising call, differentiated individuals and their motivation and did not appear to be regionally significant. Instrumental signals, while soft and easily overlooked, constituted an important intimate communication between breeding pairs.
Effects of local climate on nest cavity characteristics of a North African endemic woodpecker
Authors: Badis Mehdi , Hamdi Nabil
Published: November 2022

Levaillant’s Woodpecker Picus vaillantii is a primary cavity nester, endemic to the forests of northern Africa, including the cedar forest in Aurès Mountains. This species, similar to all woodpeckers, is important for the integrity of ecosystems, especially as it provides nesting cavities and contributes to the availability of habitats for several secondary cavity nesters that cannot excavate their hollows. This work aim to characterise the Levaillant’s Woodpecker’s nest cavities and to test the effect of local climatic conditions on the size and orientation of these cavities. Surveys were carried out in the breeding seasons of 2018 and 2019 using the point count method to search for the nests. Based on nest measurements conducted on a total of 52 available nest cavities, our results reveal that entrances are dominated by round shapes (94.2%) as compared to oval shapes. The mean height and width values of the cavity entrances were found to be 7.26 ± 1.51 centimetres and 7.11 ± 1.44 centimetres. The depth of the internal chamber and its width were estimated to be 35.42 ± 7.82 centimetres and 17.95 ± 4.01 centimetres, respectively. Unlike the average values of the volumes of the internal chamber, those relating to the entrance area and orientation vary significantly according to altitude and climatic conditions. Indeed, when climbing towards the summits, the cavities widen and turn to the west-southwest. This behaviour of the Levaillant’s Woodpecker seems to help it to benefit from maximum sunshine at high altitudes and to avoid predators and competitors more abundant at medium or low altitudes.
Effects of climate variables on the White Stork (Ciconia ciconia L.) productivity in a long term study
Authors: Gyalus Adrienn , Lovászi Péter , Végvári Zsolt , Csörgő Tibor
Published: November 2022

We analysed the effects of weather and climatic patterns on the productivity of the White Stork in Hungary between 1958 and 2017, using i) linear mixed effect models (LMM), ii) LMM-s extended by a single random effect variable or a nested combination; iii) LMM-s extended by a single fixed effect variable and iv) using an additive model of the selected variables. As a preselection, the following climatic variables were identified with substantial support: March mean temperature, March precipitation, April mean temperature, June mean temperature, June precipitation (negative), July mean temperature. The slight increase of the mean number of fledged chicks over 59 years could be the result of the increasing mean temperature, but in itself it might not be strong enough to prove that climate change will overall benefit White Stork productivity. Higher temperature and precipitation values are favourable, probably because of the higher biomass, providing more prey, but high precipitation is unfavourable until the thermoregulation of chicks is not developed. Decreasing amounts of precipitation may cause loss of wetlands as suitable feeding sites. Extreme weather is important to complement the picture given by climate change.
Ecology and “bird-habitat” relationship in the cedar forest of Aurès mountain (Eastern Algeria)
Authors: Moussouni Abdenour , Boubaker Zoubir , Chaffai Amin
Published: November 2022

This work aims to compile the birds breeding in the cedar forest of Aurès and to study the “Bird – Habitat” relationships. The data was collected using the progressive frequency sampling method that served as the basis for the diagnosis build on an analytical approach designed around three tools (mutual information, ecological profiles, modelling). Information theory tools allowed us to identify the indicator values of species as well as the most important descriptors. Habitat modelling has been prepared for species with a high indicator value. The logistic models are shown to be well adapted to the nature of the ornithological data. They related the occurrences of the species with the dendro-ecological descriptors. The 70 surveys carried out enabled us to identify 32 bird species. The ecological analysis revealed the most active descriptors and the species with high indicator value. The best-fitting models are those of Short-toed Treecreeper with positive effect of dead wood, density of trees and variability of distances between trees, and European Robin with negative effect of anthropization and general coverage, and positive effect of crown parametres. We conclude that promoting forest structural complexity by diversifying management regimes will be key to maintain avian biodiversity in cedar forests.
Optimization of Technology for the Use of Spinning Waste in Yarn Production
Authors: Kadnikova Olga , Nurmukhambetova Botagoz , Kozhabergenova Kalamkul , Omarbekova Marzhan , Sarbassova Gulmira
Published: November 2022

The paper considers issues related to the development of technology for the use of spinning waste in the production of cotton yarn. The process of forming a column of cotton fibers with included waste in an improved feeder-hopper of a loosening-scutching unit designed for cleaning from foreign impurities and dust is theoretically analysed. The optimal design parameters of an improved hopper-feeder with perforated walls have been determined depending on the performance of the loosening-scutchingunit. The approximate distribution of the concentration of foreign impurities and dust is determined depending on the technological and design features of the improved hopper-feeder with perforated walls. The optimal technological parameters of the post-treatment of the formed fibrous layer of cotton after the hopper-feeder have been determined.
MECHANISM OF COMPETITIVENESS MANAGEMENT IN THE PUBLIC HEALTHCARE: A PRACTICAL ASPECT
Authors: SHPAK Nestor , SOROCHAK Oleg , GVOZD Maryana , HORBAL Natalia , MYKHALYUNO Yuriy , SROKA Włodzimierz
Published: November 2022

Healthcare is a key element of the state's national security. The effectiveness of the healthcare industry functioning is a relevant object of research today, especially after the outbreak of the COVID-19 pandemic, during which this sector globally demonstrated its potential and problems. It necessitates a comprehensive assessment of the competitiveness of the healthcare industry and institutions as an important component of their effective management. The objects of the research are public healthcare and institutions as service organizations. The purpose is to develop a scientific-methodical approach to managing the competitiveness in the country’s healthcare industry. That is, the research is aimed at developing a market-oriented competitiveness management mechanism for public healthcare institutions. The construction of the mechanism is based on the analysis of statistical data on Ukrainian healthcare institutions according to indicators based on the "7P" marketing concept. Clustering methods, an integral indicator of competitiveness, and multidimensional methods of taxonomic analysis were also used for assessing the level of competitiveness of healthcare institutions and the comparative effectiveness of alternative measures to increase it.
Matriz curricular dos cursos de odontologia após instituição das DCN
Authors: Oliveira Alves Jesse
Published: November 2022

As Diretrizes Curriculares Nacionais (DCN) são orientações que necessitam ser adotadas por todas as instituições de ensino superior para formulação dos currículos, superando os limites acadêmicos e ofertando melhores serviços de saúde para sociedade. Historicamente, a Odontologia brasileira é marcada por diversas transformações. As DCN foram implantadas para o curso de Odontologia em 2002, iniciando a busca por uma nova organização pedagógica na qual não houvesse fragmentação de conteúdos, apresentando como uma das principais mudanças no currículo a integração das atividades acadêmicas aos serviços do SUS. Objetivo: Nesse contexto, o presente estudo, que apresenta uma abordagem exploratória comparativa e qualitativa, objetiva analisar criticamente as matrizes curriculares dos cursos de Odontologia de duas Instituições de Ensino Superior (IES), adotando como referência as DCN. Materiais e métodos: A metodologia utilizada consistiu em uma análise documental comparativa entre as matrizes curriculares dos cursos de Odontologia de duas Instituições de Ensino Superior do município de Feira de Santana- Bahia, sendo uma Estadual e uma particular, tomando como referencial uma adaptação do modelo proposto por Pessoa e Noro. Resultados: As matrizes curriculares da UEFS e da UNEF apresentam características distintas no que tange ao conteúdo curricular, organização e distribuição da carga horária, porém, as matrizes de ambas instituições cumprem com as determinações das DCN, respeitando a distribuição das disciplinas em eixos e a carga horária total. Conclusões: A implementação das DCN permitiu obter uma maior padronização entre os cursos de Odontologia das diferentes IES do Brasil, garantindo o egresso de cirurgiões-dentistas com formação de qualidade.