bluuebunny/crossref_metadata_2025 huggingface dataset:
Manipulation of the Viewer's Consciousness Through a Movie Series as a Vivid Attribute of Mass Culture
Authors: Volokhova N. V. , Postnikov A. V.
Published: November 2023

Relevance. This article examines the multifaceted influence of a cinematic work on the real life of the viewer. It is impossible to imagine your leisure time without watching any movie or TV series today. Our research focuses on the fact that the whole cinema is not only entertainment, it has a serious impact on the human psyche. At the time of such leisure, a person acquires certain value orientations, social attitudes and interests are formed, life plans and behaviors are constructed. The purpose is to assess the degree of influence of film serials on mass consciousness in modern society. Objectives: to analyze a modern multi-part cinematic work from the point of view of the formation of moral values among the younger generation; to characterize the phenomenon of a film series as a multi-part cinematic work; to characterize the phenomenon of the film series as an element of mass culture; to assess the influence of mass culture on the viewer's consciousness; to consider the phenomenon of a television series as a means of psychological influence on the recipient, and to determine the psychological mechanisms used by the communicator. Methodology. In the process of working on the study, mainly structural-diachronic, historical-biographical, hermeneutic methods, and the method of system analysis were used. Results. The results they can be used in the course of the educational process when considering issues in various courses on anthropology, philosophy of history, philosophy of culture, etc. Conclusions. In the course of the study , the following conclusions were made: watching multi-part cinematic works gives young people an idea of certain types of human behavior in society; a multi-part cinematic work or a multi-part film, we can say that this type of spectacle became the basis for the creation of a film series, its predecessor, which is why now the series is defined through the concept of a TV movie; a television series is one of the means of psychological influence through the techniques of compensatrony, identity, adaptation and counter-adaptation.
Development Prospects of Modern Banking
Authors: Averina A. S.
Published: November 2023

Relevance. The philosophy of Industry 4.0 today dictates the complete transfer of many business areas to the online environment, which has been successfully demonstrated by transformational changes in such areas as trade, communications, finance, education, public service, etc. The digital model of the national economy built on this basis is constantly being transformed and requires monitoring of the processes taking place in the information environment. It can be noted that today the world economy has reached a certain point of no return in its development, from which it is no longer possible to turn production processes from a digital model back to a traditional or analog one. The purpose of the study was to assess current trends in the digitalization of the banking sector in the face of growing competition. Objectives: to assess the current state and level of development of banking in the current socio-political conditions; to systematically present the main technological solutions that are actively implemented in banking; to highlight the key advantages of banking; to outline the horizon of banking participation in the online space. Methodology. The methods of generalization, systematization, analogy, graphical and logical analysis, idea generation were used in the work. Results. Based on a systematic vision of digitalization processes in the banking sector over the past 20 years, an analysis of the level of development of the leader of the banking business Sberbank in the world ranking, a conclusion was made about the need for further investment in technology development. Conclusions. The article discusses the directions for the future development of banking in the domestic banking sector and draws conclusions about the further development of technologies in the context of the increasing activation of generation Z in the socio-economic life of society
Integration of the Labor Market and the Institute of Education as a Factor of Socio-Economic Development of Regions: Foreign Experience
Authors: Zhukova V. S.
Published: November 2023

Relevance. The formation of human resources, reduction of unemployment, employment of graduates of professional institutions are priority tasks of both the Russian Federation and foreign countries. Human resource potential plays one of the main roles in ensuring the welfare and economic growth of the state. A direct participant in the process of "creating" a promising specialist is a professional educational institution, where the modern educational trajectory provides for the formation of competitive personalities. Given the rapid growth rates of the economy in different regions, the real business sector needs qualified personnel, where the modern foreign labor market imposes its own requirements for skills and competencies, taking this into account, universities use tools for the effective participation of graduates in competitive market relations.The purposeis to consider foreign models of promoting the employment of graduates, to study the tools of integration of universities and enterprises in the field of employment.Objectives: to analyze the means and methods implemented by foreign countries in the process of integrating the labor market and the institute of education. To formulate the main aspects of the implementation of foreign models to promote the employment of graduates.Methodology. In this work, the following research methods were used: analysis, synthesis, generalization and logical methods of information processing.Results. The main aspects of the implementation of foreign models of facilitating the employment of graduates are formulated, an analysis of the means and methods implemented by foreign states in the process of integrating the labor market and the institution of education is carried out. In addition, methods are proposed to improve planning and coordination of actions related to labor potential in the youth labor market.Conclusions.In the framework of cooperation between universities and enterprises in the field of employment of graduates in a number of foreign countries, an insufficient number of means and methods are used. For more effective interaction between the parties, a set of measures has been presented that will help improve the situation on the youth labor market.
Transformation of the Personnel Policy of a Manufacturing Enterprise in the Corporate Governance System
Authors: Karpova E. N. , Vozniuk V. V.
Published: November 2023

Relevance. The trajectory of the organization's development in modern conditions requires managers to take an updated approach to personnel management, namely, from the perspective of human resource management. The purpose of the study is to study and analyse the implementation of personnel policy on the example of the production enterprise LLC "Hydrophob", to determine the directions of its improvement. Objectives: study of the theoretical foundations of the formation of personnel policy in the organization; evaluation of the activities of the production enterprise LLC "Hydrophob" in terms of its human resources potential; development of measures to improve the personnel policy of LLC "Hydrophob". Methodology. To solve the tasks set in the course of the study, the dialectical method of cognition of the phenomena of objective reality was used, as well as methods of analysis, synthesis, systematization of information, content analysis of data, graphical method. Results: the interrelation of the concepts of "personnel policy", "labor resources" and "labor potential" of the organization is revealed; the analysis of the effectiveness of personnel policy was carried out on the example of the production enterprise LLC "Hydrophob", which allowed to identify bottlenecks that need to be eliminated; recommendations for improving the personnel policy of the analysed organization are proposed. Conclusions. The results of the quantitative analysis of the workforce of the production enterprise LLC "Hydrophob" demonstrate a trend of growth in staffing for all groups of employees in 2022 compared to 2021, a high proportion of workers in the overall structure of the workforce. The results of a qualitative analysis of the labor resources of the analyzed enterprise allow us to conclude that there is a low proportion of young professionals in the organization; that employees have the necessary level of qualification (education); most employees have a long work experience (15-20 years) in the organization. Based on the obtained analytical results, possible directions for improving the personnel policy of the production enterprise LLC "Hydrophob" are proposed by creating a personnel reserve using internal and external sources.
Technologies as a Source of State Management of Technological Development in the Context of Digital Transformation
Authors: Obukhova A. S. , Svezhentseva K. I.
Published: November 2023

Relevance. In modern conditions, there is a significant transformation of the business sector. Technological development becomes the driving force of economic growth and the object of the country's strategic development, since technological enterprises form the basis of technological development. Currently, there are several types of entrepreneurial structures that take place in the modern economy: technological entrepreneurship; entrepreneurship of digital technologies; digital business. In modern conditions, scientific and technological progress is accelerating at a double rate, as the information space is expanding both inside and outside the country. The development of technological entrepreneurship requires a developed innovation ecosystem that creates favorable conditions for the creation of advanced technologies and technological solutions. Modern entrepreneurship is developing in various directions, based on advanced technologies and digital transformation. Despite the rapid technological growth of Russian companies, there are a number of problems hindering further development. However, in the current conditions of sanctions pressure and a complex geopolitical situation, the technology sphere on the Russian territory is waiting for big changes in terms of infrastructure and institutional issues, which determines the relevance of the scientific research presented in this paper. The purpose of the study is to substantiate the role of public administration in innovation and technological development. Objectives: to consider the mechanism of state regulation and state support for technological entrepreneurship and to analyze the current state of innovation and technological development. Methodology. The study is based on a review of the works of domestic economists, the study of the regulatory framework on the research topic and the analysis of statistical data. Results. In the course of the work, the current state of the technological development of the Russian Federation was analyzed, the key indicators of innovative and technological development were analyzed, the main problems and features of technological entrepreneurship at the present stage were characterized, the legal framework for technological development, which forms the structure and principles of the functioning of the technology market, was considered. Conclusions. Based on the results of the study, it can be concluded that in the near future the state is waiting for the development of the domestic technology market, which contributes to technological development.
Analysis of the Rational Use of Forest Resources in Sparsely Forested Regions (on the Example of the Central Black Earth Region)
Authors: Marchuk I. I. , Panyavina E. A. , Zinovieva I. S.
Published: November 2023

Relevance. The world trends in the modern forest resources use result into disasters i.e. the death and deterioration of forest resources, the degeneration of natural forests, carbon dioxide increase in the atmosphere, a decrease in timber reserves, etc. So, rational use of forest resources are vital, especially in poorly forested regions, for these forests do not have great raw material resources, they are protective, and, require a special approach in their use. The purpose is to study and to analyze the use of forest resources on the base of the example of the Central Chernozem region (CDR) as a small-bodied one. The objectives is to form the ideas and to determine the priority areas for the use of forest resources in poorly forested regions. Methodology. The official statistics reference books of the Federal State Statistics Service of the Russian Federation were used during the research process as well as Web resources materials (official sites), mass media information. Results. The rational use of forest resources in poorly forested regions are based upon the next functions ‒ preserving their environment-forming, water-protective, health protective functions So, the use of these resources are to be analyzed to determine the future criteria and rational use methods. Conclusions. The forests of poorly forested regions are different in a number of features: they are protective, they do not have exploitation functions, and they are extremely important, so their rational use is a priority. The analysis of the use of forest resources in poorly forested regions (based upon the example of the Central Black Soil Region) will further contribute much to the formation of priority areas to conserve their resources and environmental component with the particular value for the country and for the regions both.
Case-Based Serious Gaming for Complication Management in Colorectal and Pancreatic Surgery: Prospective Observational Study
Authors: Schwarzkopf Sophie-Caroline , Distler Marius , Welsch Thilo , Krause-Jüttler Grit , Weitz Jürgen , Kolbinger Fiona R
Published: November 2023

Background

The potential risk and subsequent impact of serious complications after pancreatic and colorectal surgery can be significantly reduced through early recognition, correct assessment, and timely initiation of appropriate therapy. Serious gaming (SG) is an innovative teaching method that combines play with knowledge acquisition, increased concentration, and quick decision-making and could therefore be used for clinically oriented education.

Objective

This study aims to develop a case-based SG platform for complication management in pancreatic and colorectal surgery, validate the application by comparing game courses of various professional groups in the health care sector, and test the acceptance of the developed platform in the context of clinical education by measuring levels of usability and applicability within the framework of a validity and usefulness analysis.

Methods

In this observational trial, a novel SG for management of postoperative complications was developed and prospectively validated in a cohort of 131 human caregivers with varying experience in abdominal surgery. A total of 6 realistic patient cases were implemented, representing common complications after pancreatic and colorectal surgery. Cases were developed and illustrated using anonymized images, data, and histories of postoperative patients. In the prospective section of this study, following a brief case presentation, participants were asked to triage the virtual patient, make an initial suspected diagnosis, and design a 3-step management plan, throughout which the results of selected diagnostic and therapeutic actions were presented. Participants’ proposed case management was compared to ideal case management according to clinical guidelines. Usability, applicability, validity, and acceptance of the application were assessed using the Trier Teaching Evaluation Inventory as part of a noncomparative analysis. In addition, a comparative analysis of conventional teaching and learning formats was carried out.

Results

A total of 131 cases were answered. Physicians selected more appropriate therapeutic measures than nonphysicians. In the Trier Teaching Evaluation Inventory, design, structure, relevance, timeliness, and interest promotion were predominantly rated positively. Most participants perceived the application to be superior to conventional lecture-based formats (training courses, lectures, and seminars) in terms of problem-solving skills (102/131, 77.9%), self-reflection (102/131, 77.9%), and usability and applicability (104/131, 79.4%).

Conclusions

Case-based SG has educational potential for complication management in surgery and could thereby contribute to improvements in postoperative patient care.
Use of e-Cigarettes in Cigarette Smoking Cessation: Secondary Analysis of a Randomized Controlled Trial
Authors: Santiago-Torres Margarita , Mull Kristin E , Sullivan Brianna M , Bricker Jonathan B
Published: November 2023

Background

Many adults use e-cigarettes to help them quit cigarette smoking. However, the impact of self-selected use of e-cigarettes on cigarette smoking cessation, particularly when concurrently receiving app-based behavioral interventions, remains unexplored.

Objective

This study used data from a randomized trial of 2 smartphone apps to compare 12-month cigarette smoking cessation rates between participants who used e-cigarettes on their own (ie, adopters: n=465) versus those who did not (ie, nonadopters: n=1097).

Methods

The study population included all participants who did not use e-cigarettes at baseline. “Adopters” were those who self-reported the use of e-cigarettes at either 3- or 6-month follow-ups. “Nonadopters” were those who self-reported no use of e-cigarettes at either follow-up time point. The primary cessation outcome was self-reported, complete-case, 30-day point prevalence abstinence from cigarette smoking at 12 months. Secondary outcomes were missing-as-smoking and multiple imputation analyses of the primary outcome, prolonged abstinence, and cessation of all nicotine and tobacco products at 12 months. In logistic regression models, we first examined the potential interaction between e-cigarette use and treatment arm (iCanQuit vs QuitGuide) on the primary cessation outcome. Subsequently, we compared 12-month cigarette smoking cessation rates between adopters and nonadopters separately for each app.

Results

There was suggestive evidence for an interaction between e-cigarette use and treatment arm on cessation (P=.05). In the iCanQuit arm, 12-month cigarette smoking cessation rates were significantly lower among e-cigarette adopters compared with nonadopters (41/193, 21.2% vs 184/527, 34.9%; P=.003; odds ratio 0.55, 95% CI 0.37-0.81). In contrast, in the QuitGuide arm, 12-month cigarette smoking cessation rates did not differ between adopters and nonadopters (46/246, 18.7% vs 104/522, 19.9%; P=.64; odds ratio 0.91, 95% CI 0.62-1.35).

Conclusions

The use of e-cigarettes while concurrently receiving an app-based smoking cessation intervention was associated with either a lower or an unimproved likelihood of quitting cigarette smoking compared to no use. Future behavioral treatments for cigarette smoking cessation should consider including information on the potential consequences of e-cigarette use.

Trial Registration

ClinicalTrials.gov NCT02724462; https://clinicaltrials.gov/study/NCT02724462
Detection of Urinary Misfolded Proteins for Imminent Prediction of Preeclampsia in Pregnant Women With Suspected Cases: Protocol for a Prospective Noninterventional Study (Preprint)
Authors: Tang Haiyang , Tian Yijia , Fang Jing , Yuan Xiaoying , Yao Minli , Wang Yujia , Feng Yan , Shu Jia , Ni Yan , Yu Ying , Wang Yuanhe , Liang Ping , Li Xingmin , Bai Xiaoxia
Published: November 2023

BACKGROUND

Preeclampsia (PE) is one of the most common hypertensive diseases, affecting 2%-8% of all pregnancies. The high maternal and fetal mortality rates of PE are due to a lack of early identification of affected pregnant women that would have led to closer monitoring and care. Recent data suggest that misfolded proteins might be a promising biomarker for PE prediction, which can be detected in urine samples of pregnant women according to their congophilia (aggregated) characteristic.

OBJECTIVE

The main purpose of this trial is to evaluate the value of the urine congophilia-based detection of misfolded proteins for the imminent prediction of PE in women presenting with suspected PE. The secondary objectives are to demonstrate that the presence of urine misfolded proteins correlates with PE-related maternal or neonatal adverse outcomes, and to establish an accurate PE prediction model by combining misfolded proteins with multiple indicators.

METHODS

At least 300 pregnant women with clinical suspicion of PE will be enrolled in this prospective cohort study. Participants should meet the following inclusion criteria in addition to a suspicion of PE: ≥18 years old, gestational week between 20+0 and 33+6, and single pregnancy. Consecutive urine samples will be collected, blinded, and tested for misfolded proteins and other PE-related biomarkers at enrollment and at 4 follow-up visits. Clinical assessments of PE status and related complications for all participants will be performed at regular intervals using strict diagnostic criteria. Investigators and participants will remain blinded to the results. Follow-up will be performed until 42 days postpartum. Data from medical records, including maternal and fetal outcomes, will be collected. The performance of urine misfolded proteins alone and combined with other biomarkers or clinical variables for the prediction of PE will be statistically analyzed.

RESULTS

Enrollment started in July 2023 and was still open upon manuscript submission. As of March 2024, a total of 251 eligible women have been enrolled in the study and enrollment is expected to continue until August 2024. Results analysis is scheduled to start after all participants reach the follow-up endpoint and complete clinical data are collected.

CONCLUSIONS

Upon completion of the study, we expect to derive an accurate PE prediction model, which will allow for proactive management of pregnant women with clinical suspicion of PE and possibly reduce the associated adverse pregnancy outcomes. The additional prognostic value of misfolded proteins is also expected to be confirmed.

CLINICALTRIAL

Chinese Clinical Trials Registry ChiCTR2300074878; https://www.chictr.org.cn/showproj.html?proj=202096

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/54026
Leveraging AI and Machine Learning to Develop and Evaluate a Contextualized User-Friendly Cough Audio Classifier for Detecting Respiratory Diseases: Protocol for a Diagnostic Study in Rural Tanzania (Preprint)
Authors: Isangula Kahabi Ganka , Haule Rogers John
Published: November 2023

BACKGROUND

Respiratory diseases, including active tuberculosis (TB), asthma, and chronic obstructive pulmonary disease (COPD), constitute substantial global health challenges, necessitating timely and accurate diagnosis for effective treatment and management.

OBJECTIVE

This research seeks to develop and evaluate a noninvasive user-friendly artificial intelligence (AI)–powered cough audio classifier for detecting these respiratory conditions in rural Tanzania.

METHODS

This is a nonexperimental cross-sectional research with the primary objective of collection and analysis of cough sounds from patients with active TB, asthma, and COPD in outpatient clinics to generate and evaluate a noninvasive cough audio classifier. Specialized cough sound recording devices, designed to be nonintrusive and user-friendly, will facilitate the collection of diverse cough sound samples from patients attending outpatient clinics in 20 health care facilities in the Shinyanga region. The collected cough sound data will undergo rigorous analysis, using advanced AI signal processing and machine learning techniques. By comparing acoustic features and patterns associated with TB, asthma, and COPD, a robust algorithm capable of automated disease discrimination will be generated facilitating the development of a smartphone-based cough sound classifier. The classifier will be evaluated against the calculated reference standards including clinical assessments, sputum smear, GeneXpert, chest x-ray, culture and sensitivity, spirometry and peak expiratory flow, and sensitivity and predictive values.

RESULTS

This research represents a vital step toward enhancing the diagnostic capabilities available in outpatient clinics, with the potential to revolutionize the field of respiratory disease diagnosis. Findings from the 4 phases of the study will be presented as descriptions supported by relevant images, tables, and figures. The anticipated outcome of this research is the creation of a reliable, noninvasive diagnostic cough classifier that empowers health care professionals and patients themselves to identify and differentiate these respiratory diseases based on cough sound patterns.

CONCLUSIONS

Cough sound classifiers use advanced technology for early detection and management of respiratory conditions, offering a less invasive and more efficient alternative to traditional diagnostics. This technology promises to ease public health burdens, improve patient outcomes, and enhance health care access in under-resourced areas, potentially transforming respiratory disease management globally.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/54388
Self-Management Interventions for Facilitating Life Participation for Persons with Kidney Failure
Authors: Moreels Timothy , Van de Velde Dominique , Goethals Justine , Vanden Wyngaert Karsten , De Baets Stijn , Nagler Evi , Leune Tamara , De Vriendt Patricia , Van Biesen Wim
Published: November 2023

Background

For persons with kidney failure, life participation is a critically important outcome, strongly linked to quality of life and mortality. To support patients' self-management abilities, three domains are typically emphasized: medical management, emotional management, and management of everyday life (i.e., role management). Although role management is strongly linked to life participation, there is currently limited research on interventions designed to support it. We explored existing self-management interventions that aim to support everyday life functioning, rather than only medical management.

Methods

In this systematic review and qualitative meta-synthesis, we searched MEDLINE, Embase, CINAHL, PsycINFO, Web of Science, and CENTRAL up to April 2022 for interventional studies involving self-management interventions designed, at least partly, to support management of everyday life. The guidelines by Sandelowski and Barosso were used to analyze and synthesize the results. A taxonomy of everyday self-management strategies was used to further explore intervention content. Study quality was assessed using the Cochrane Collaboration risk-of-bias tools. Evidence of effectiveness was summarized, and a meta-analysis of eligible outcomes was conducted.

Results

Of 22,667 records, 53 studies were included in the meta-synthesis. Most self-management interventions focused on medical management. Included interventions involved strategies to support eight domains: Activities of daily living, Work and school life, Meaningful occupations, Leisure activities, Mobility and travel, Interpersonal relationships, Role functioning, and Social participation. Major interventions focused on providing education, skill training, counseling, and cognitive behavioral therapy. Evidence of effectiveness was reported across a wide range of patient-reported outcomes, including (health-related) quality of life, depression, and self-efficacy. Studies were geographically concentrated and were of moderate to low quality.

Conclusions

Despite its well-recognized importance, research on interventions to improve life participation mostly consisted of pilot and feasibility studies and studies of low quality. Interventions were reported heterogeneously, limiting comparability, and were restricted to specific regions and cultures, limiting generalizability.
College Admission Prediction using Machine Learning
Authors: Narnaware Monu
Published: November 2023

Students struggle mightily to get accepted into the college of their choice. The present engineering admission process is little challenging when it comes to picking the right college based on test results and areas of interest. The candidates' ability to complete the application form accurately depends on their selection, which may differ depending on their academic performance and entrance exam results. Numerous colleges provide a variety of engineering courses. Students find it difficult to arrange and list the appropriate institutions of their choice for courses based on their performance score. The historical college cut-off data used by the college admission predictor to determine the most likely colleges.
Implementasi Pembelajaran STEM Low Cost di Sekolah Dasar untuk Mengembangkan Keterampilan Abad 21
Authors: Kumala Shifni Afida , Sa'dijah Cholis , Hadi Syamsul
Published: November 2023

Students in the 21st-century era must have many skills. There needs to be learning that supports an independent curriculum and project-based learning. Meanwhile, schools still carry out their learning activities using the lecture method, which is less meaningful and has yet to explore students' abilities fully. STEM is a skill and knowledge acquired simultaneously by students. The aims of this study are that researchers want to obtain deeper information about 1) the background of STEM-based learning at SDI Aisyiyah, 2) the implementation of STEM-based learning at SDI Aisyiyah, and 3) the skills students acquire during STEM-based learning at SDI Aisyiyah. Researchers want to obtain more in-depth information about the background of learning in the school, the application of STEM learning in the school, and the skills that can be formed from STEM-based learning. This research uses a qualitative method whose data processing uses NVivo12. Nvivo 12 is the latest version of the application for processing qualitative research data. The research findings support 21st-century learning, project learning during a pandemic, implementing an independent curriculum, providing STEM training, creating fun learning and creating a low-cost STEM culture. STEM learning is held once a week. The syntax in STEM learning at SDI Aisyiyah is as follows: 1. The teacher selects and breaks down KD/TP in learning, 2. Giving triggering questions or problems, 3. Finding solutions or problem-solving by teachers and students, 4. Product design, 5. Product presentation or presentation, 6. Product correction and evaluation, and the last is product revision. Some of the skills that can be formed from STEM learning at SDI Aisyiyah are being able to work together, being able to think complexly, having an artistic spirit, being a more communicative, more creative child, being independent, etc.
Conflito familiar e envolvimento parental: percepções de filhos adolescentes
Authors: Mosmann Clarisse Pereira , Da Costa Cristofer Batista , Schaefer Jeferson Rodrigo , Peloso Franciele Cristiane
Published: November 2023

Os conflitos familiares e o baixo envolvimento parental podem ter repercussões no desenvolvimento dos filhos. Por isso, o objetivo deste estudo foi investigar as percepções de adolescentes, membros de famílias nucleares e separadas sobre o envolvimento parental e os conflitos familiares, assim como suas possíveis repercussões em sintomas internalizantes e externalizantes. Trata-se de uma pesquisa qualitativa realizada em três escolas públicas, através de grupos focais e que envolveu dezenove adolescentes que responderam também um questionário sociodemográfico e o Youth Self-Report. Através de análises estatísticas descritivas verificou-se que parte da amostra apresentou sintomas clínicos. As conversações nos grupos focais foram submetidas à análise de conteúdo e originaram as categorias: conflitos familiares, envolvimento parental, sintomas internalizantes e sintomas externalizantes. Os resultados possibilitaram compreender como as interrelações familiares são percebidas pelos filhos e impactam sua forma de pensar, sentir e agir sugerindo a necessidade de espaços de acolhimento e escuta aos jovens.
Study of the Prophet's Prediction Hadith
Authors: Yahya Agusni
Published: November 2023

This study aims to describe the interpretation of prophetic hadiths concerning the predictions by the Prophet as a guide for the future and how the methodology of understanding hadith contributes to a correct interpretation of these statements. This study uses a qualitative approach with a literature review method. This study showed that the predictions made by Prophet Muhammad in hadiths about the state of the community are not necessarily meant to be seen as inevitable destinies but rather as events that will unfold. The negative interpretations of these predictions have led to a loss of relevance in the present era. However, by understanding the distinctive characteristics of hadiths and applying the knowledge of fiqh al-hadith, one can better comprehend the statements of Prophet Muhammad SAW.
The Meaning of the Word “Wazir” in the Qur’an: A Semantic Analysis
Authors: Nur Rochim Mohammad Rizal , Nugroho Kharis , Nirwana Andri
Published: November 2023

The purpose of this study is to explore and understand the meaning of the word "wazir" in the Quran. This study employs a library research method, which requires the researcher to conduct a thorough examination of various textual sources and literature related to the word. The approach used in this research is Toshihiko Izutsu's Quranic semantic approach. The research findings indicate that the meaning of the word "wazir" in the Quran is complex, with strong connotations related to the concepts of sin and heavy or significant accountability. Understanding the word "wazir" is crucial, as it not only reflects linguistic understanding but also has profound moral and ethical implications in Islam. Semantic analysis of the word "wazir" provides insights for a deeper understanding of the moral and ethical values embedded in the Quran, as well as how this vocabulary reflects and portrays the fundamental principles of the religion in the sacred text.
A systematic literature review on the fishermen's knowledge of integrating fishing and tourism activities
Authors: Roslan Faros Fadzira , Zainol Rosilawati , Rosni Nur Aulia
Published: November 2023

Education for the future requires everyone to consider the pillars of sustainability in carrying out their daily activities. It is crucial to note that education is an essential ingredient in achieving sustainable development. Fishermen, for example, live in poverty due to a lack of proper knowledge and learning exposure. Having greater insight into this research area would yield helpful information about the impact of education on the fishermen's community's well-being. The integration of fishing and tourism disciplines is ongoing and has produced positive results. An in-depth examination at how fishing and tourism might work together is presented here for the first time. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) publication standard has been employed as a key research design approach. Web of Science and Scopus are the two key databases used in this study. A total of eleven (11) articles are eligible for review and analysis. Three (3) themes emerged from the thematic analysis, namely, 1) fishing and tourism, 2) knowledge, and 3) rural economies. This study proposes two (2) recommendations. To begin, there is a dire need for additional qualitative research because it is the only method to deliver comprehensive and precise knowledge. Second, authors can report reviews on any study in a systematic manner when they use the PRISMA method.
Bimbingan teknis pengelolaan nomor induk berusaha (NIB) berbasis online single submittion (OSS) bagi pelaku UMKM Binaan Perkumpulan Rumah Pintar Di Kabupaten Kuningan
Authors: Purnomo  , Wahyudin Uyu , Kamil Mustofa , Kamarubiani Nike , Suryadi Ace , Faisal Najmudin Muhammad
Published: November 2023

Masih terdapat beberapa UMKM di Kabupaten Kuningan yang belum memiliki legalitas atau izin usaha, serta menimbulkan dampak menurunnya terhadap akses pasar dan pertumbuhan usahanya. Namun, penerapan Nomor Induk Berusaha (NIB) melalui Online Single Submittion (OSS) seringkali masih menjadi kendala bagi pelaku usaha, terutama pelaku UMKM yang kurang memahami proses dan persyaratan yang diperlukan. Tujuannya pengabdian pada masyarakat ini adalah memberikan solusi melalui bimbingan teknis mengenai pengelolaan dan pembuatan NIB berbasis OSS. Metode implementasi melibatkan 40 pelaku UMKM yang merupakan binaan Rumah Pintar Provinsi Jawa Barat, dengan kegiatan dilaksanakan pada Kamis, 3 Agustus 2023, di Graha Wisesa, Dinas Tenaga Kerja dan Transmigrasi Kabupaten Kuningan. Metode bimbingan teknis, melalui tahap perencanaan, pengorganisasian, pelaksanaan, dan evaluasi diterapkan untuk mengoptimalkan pemahaman mengurus NIB dan izin usaha melalui platform OSS. Hasilnya menunjukkan peningkatan pemahaman para pelaku UMKM tentang pentingnya NIB, memperluas akses pasar, dan mengurangi hambatan birokrasi. Program inimengurangi rintangan birokrasi, membuka peluang pasar yang lebih luas, serta meningkatkan kredibilitas dan potensi pertumbuhan UMKM di wilayah Kabupaten Kuningan.
Advances of natural polyphenol based anti-oxidant nanomaterials for efficient treatment of inflammatory bowel disease
Authors: Wang Liucan , Yang Yang , Xu Chao , Zhu Li , Chen Guoqing , Yang Hua , Yu Min
Published: November 2023

Excessive generation of reactive oxygen species (ROS) resulting in
oxidative stress and plays a crucial role in the progression of
inflammatory bowel disease (IBD), which may in turn serve as a potential
therapeutic target. To date, efforts on ROS scavenging systems have been
focused predominantly on metal oxide nanoenzymes and polyphenol-based
nanomaterials. Polyphenols, as a natural plant extract, have attracted
increasing interests and showed great antioxidant properties in IBD
therapy. The unique catechol groups in polyphenols allowing them to
interact with biomolecules, such as proteins and nucleic acids.
Additionally, the strong metal ion chelating ability of catechol
enriched the structure and function of nanomaterials. This
characteristic not only improves the physicochemical properties of
polyphenols based nano-carriers but also enables innovative designs of
multifunctional drug delivery systems (DDSs). To date, research on
polyphenol-based DDSs has increased, including epigallocatechin gallate
(EGCG), curcumin (CUR), resveratrol, tannic acid (TA), rosmarinic acid
(RA) and dopamine (DA). In this review, we mainly focus on the design
and application of natural polyphenol based nanomaterials in IBD,
providing a comprehensive discussion on the use of polyphenols in DDSs.
We will also discuss the potential challenges in innovative drug
delivery strategies, including their impact on the physical and chemical
properties of drug delivery systems.
Long-distance Southern Ocean environmental DNA (eDNA) transect provides insights into spatial marine biota and invasion pathways for non-native species
Authors: Nester Georgia , Suter Leonie , Kitchener John , Bunce Michael , Polanowski Andrea , Wasserman Johan , Deagle Bruce
Published: November 2023

The Southern Ocean surrounding Antarctica harbours some of the most
pristine marine environments remaining, but is increasingly vulnerable
to anthropogenic pressures, climate change, and invasion by non-native
species. Monitoring biotic responses to cumulative impacts requires
spatiotemporal baselines and ongoing monitoring - traditionally, this
has been obtained by continuous plankton recorder (CPR) surveys. Here,
we conduct a 3000 nautical mile environmental DNA (eDNA) transect from
Hobart (Australia) to Davis Station (Antarctica). We evaluate eDNA
sampling strategies for long-term open ocean biomonitoring by comparing
two water volume and filter pore size combinations: large (12 L with 20
μm) and small (2 L with 0.45 μm). Employing a broad COI metabarcoding
assay, we found the large sample/pore combination was better suited to
open-ocean monitoring, detecting more target DNA and rare or low
abundance species. Comparisons with four simultaneously conducted CPR
transects revealed that eDNA detections were more diverse than CPR, with
7 (4 unique) and 4 (1 unique) phyla detections respectively. While both
methods effectively delineated biodiversity patterns across the Southern
Ocean, eDNA enables surveys in the presence of sea-ice where CPR cannot
be conducted. Accordingly, 16 species of concern were detected along the
transect using eDNA, notably in the Antarctic region (south of 60°S).
These were largely attributed to hull biofouling, a recognized pathway
for marine introductions into Antarctica. In a warming Southern Ocean,
continued biomonitoring is vital for conserving Antarctic ecosystems. We
advocate for the long-term implementation of eDNA metabarcoding
alongside CPR surveys to facilitate ecosystem-based management of these
vulnerable environments.
Speciation due to rapid genetic divergence in coding and noncoding regions accompanied by phenotypic differences in the tabular coral Acropora
Authors: Furukawa Mao , Kitanobo Seiya , Ohki Shun , Teramoto Mariko , Hanahara Nozomi , Morita Masaya
Published: November 2023

The reef-building coral genus Acropora is essential for coral
reefs due to its role in the reef, as a habitat for other marine
organisms. The diversity of coral species might have arisen explosively,
accompanied by hybridization in response to historical climate change,
Pleistocene, with sea level changes. Here, we aimed from integrative
approaches (morphology, genetics, and reproduction) to evaluate the
speciation history of the four tabular Acropora species
(Acropora aff hyacinthus, A. cf bifurcata,
A. cf cytherea, and A. cf subulata). Here,
we show that introgression might have a minor role in specifying the
four tabular Acropora spp. Instead, rapid genetic divergence
occurred, accompanied by morphological differences and gamete
incompatibility. Furthermore, extensive morphological analyses showed
that these four species were distinguishable from morphology, and their
gamete incompatibility was sufficiently high to prevent hybridization.
Population structure and principal component analyses with the SNPs
(>60,000) indicated these four species were also
distinctive, and the ABBA-BABA test did not support introgression among
these species. In addition, many coding and noncoding RNA sequences were
in the high genetic variances among four species with high Fst loci
along the genome. Comparing these orthologs among other Acropora
species suggests that many of these genes were under positive selection,
which could be associated with their divergence at spawning time, gamete
incompatibility, and morphological differences. These results show that
the speciation of the tabular Acropora occurred without
hybridization, and divergence accompanying the genes’ rapid evolution
could be associated with specifying in the species-rich Acropora.
A Comprehensive Systematic Review of Intra-Articular Corticosteroids: Symptom and Disease Modification Osteoarthritis Effects and the Potential Impact on Healthy Joints (Part 1)
Authors: Tokawa Paula Keiko Anadão , Baccarin Raquel , Zanotto Gustavo
Published: November 2023

Background: The importance of intra-articular corticosteroid treatment
for osteoarthritis with its possible adverse effects requires a
comprehensive review. Objectives: This review answers the following
questions: 1) What evidence is available regarding the symptom-modifying
and disease-modifying changes related to a single intra-articular
corticosteroid injection for treating osteoarthritis? Moreover, 2) What
evidence suggests corticosteroids are detrimental to equine joint
health? Study design: Systematic review. Methods: A systematic search
was conducted in June/2022 in PubMed, CAB, and the Web of Science.
Inclusion criteria were applied to titles and abstracts. For each
question, further criteria were applied. The risk of bias was assessed
according to the study design. Results: We generated 6,417 titles, and
23 articles fit all inclusion criteria for single-injection
corticosteroid treatments; 21 were included regarding corticosteroid
effects on joint health. Studies were usually rated as having an unclear
risk of bias. Single-injection protocols lead to short-term
symptom-modifying osteoarthritic changes with conflicting results
regarding disease-modifying osteoarthritis. Healthy joints demonstrated
disturbances in metabolism and tissue changes, with dose-dependent
effects found in vitro. Main limitations: There is a lack of studies
regarding the topics–primarily for equine species. Conclusions:
Symptom-modifying osteoarthritic changes after a single injection are
short-term; however, a consistent disease-modifying osteoarthritis
effect is yet to be established. Joint health appears to be disturbed by
corticosteroids as their effects on normal joints show adverse changes
in tissues and metabolism.
Doenças raras: diretrizes clínicas elaboradas no contexto do Sistema Único de Saúde nos últimos 11 anos
Authors: Gomes Rosângela Maria , Guedes de Sousa Esashika Suely Nilsa , Teixeira Vida Ávila , Da Cunha Lobo Souto Maior Marta , Fontes Schluckebier Bonan Luciene
Published: November 2023

Introdução: Define-se doenças raras como aquelas que afetam até 65 pessoas em cada 100.000 indivíduos. No Brasil, aproximadamente 13 milhões de pessoas têm doenças raras (6% da população brasileira). Os Protocolos Clínicos e Diretrizes Terapêuticas são especialmente importantes para orientar o diagnóstico e o tratamento de pacientes com doenças raras. A Comissão Nacional de Incorporação de Tecnologias em Saúde (Conitec) assessora o Ministério da Saúde (MS) no desenvolvimento de Protocolos Clínicos e Diretrizes Terapêuticas. A elaboração ou atualização desses documentos é baseada em evidência científica e considera critérios de eficácia, segurança, efetividade e custo-efetividade das tecnologias recomendadas. Além de serem orientadas por diretrizes metodológicas estabelecidas pelo MS. Objetivos: Apresentar os Protocolos Clínicos e Diretrizes Terapêuticas desenvolvidos no âmbito do Ministério da Saúde nos últimos onze anos. Material e Método: Estudo qualitativo descritivo sobre o processo de elaboração e atualização de Protocolos Clínicos e Diretrizes Terapêuticas para doenças raras pela Conitec no âmbito do Sistema Único de Saúde. A coleta e análise dos dados foi realizada pelo software Excel, 2010. A análise considerou os guias elaborados ou atualizados que foram avaliados pela Conitec e publicados no período de 2012 a 2022. Resultados: O Ministério da Saúde publicou 179 Protocolos Clínicos e Diretrizes Terapêuticas até dezembro de 2022. Dentre essas, 63 (35%) são diretrizes para doenças raras, como Fibrose cística, Miastenia Gravis, Atrofia Muscular Espinhal- AME, Esclerose Lateral Amiotrófica. No período de 2012 a 2022 foram elaboradas e atualizadas 108 diretrizes para doenças raras pela Conitec. Dessas, 31 (43,6%) eram novas diretrizes clínicas e as demais eram atualizações. Em média, 9,8 diretrizes clínicas para doenças raras foram elaboradas e atualizadas por ano (desvio padrão ± 3,7). A série histórica de publicação de diretrizes clínicas sobre doenças raras revelou que o maior número de diretrizes (n=15) foi publicado em 2018 e o menor número (n=3) em 2012. As novas diretrizes foram publicadas, em sua maioria, no ano de 2019. Já entre 2016 e 2017, não houve publicação de novas diretrizes. Discussão e Conclusões: O Ministério da Saúde vem investindo na produção e atualização de Protocolos Clínicos e Diretrizes Terapêuticas com vistas à qualificação da atenção à saúde prestada às pessoas com doenças raras. A elaboração e atualização das diretrizes clínicas, a partir da melhor evidência científica disponível, contribui para a melhoria da qualidade de vida dos pacientes com doenças raras e são importante ferramenta para a gestão e regulação do uso de medicamentos e outras tecnologias de saúde.