bluuebunny/crossref_metadata_2025 huggingface dataset:
A Modified Range Migration Algorithm for FMCW SAR Signal Processing
Authors: Yake Li , Young Siu O’
Published: November 2019

The range migration algorithm (RMA) is an accurate imaging method for processing synthetic aperture radar (SAR) signals. However, this algorithm requires a big amount of computation when performing Stolt mapping. In high squint and wide beamwidth imaging, this operation also requires big memory size to store the result spectrum after Stolt mapping because the spectrum will be significantly expanded. A modified Stolt mapping that does not expand the signal spectrum while still maintains the processing accuracy is proposed in this paper to improve the efficiency of the RMA when processing frequency modulated continuous wave (FMCW) SAR signals. The modified RMA has roughly the same computational load and required memory size as the range Doppler algorithm (RDA) when processing FMCW SAR data. In extreme cases when the original spectrum is significantly modified by the Stolt mapping, the modified RMA achieves better focusing quality than the traditional RMA. Simulation and real data are used to verify the performance of the proposed RMA.
NATIONAL SELF-CONSCIOUSNESS OF STUDENTS IN HIGHER EDUCATIONAL STUDIES IN THE REPUBLIC OF TATARSTAN BY MEANS OF HUMANITARIAN DISCIPLINES
Authors: F. Dulmukhametova Gulnara , Sattarova Adelia , R. Fakhrutdinov Rail , R. Khairutdinov Ramil
Published: November 2019

Purpose: The article describes the view of the author to the actualization of national consciousness of students by means of humanitarian disciplines. The processes of globalization and integration of Tatarstan Republic into the world space exacerbate the problem of preserving the uniqueness and identity, national cultures in the conditions of cultural diversity.

Methodology: To solve the problems, we used the following research methods: theoretical (study and analysis of philosophical, psychological, ethnological, sociological, pedagogical, cultural, linguistic, methodological and other literature on the research topic); empirical (pedagogical observation, group and individual conversations, oral and written surveys, testing, questioning, pedagogical experiment); mathematical methods (registration of obtained data, method of mathematical processing of experimental research results).

Result: The analysis of the research showed that developed national self-consciousness promotes spiritual development and self-development of the individual. National self-consciousness is the recognition of belonging to a certain national community, along with a positive assessment of representatives of other national cultures, the individual's representation of language, culture, typical features of the community, the common historical past, religion, territory, and statehood.

Applications: This research can be used for the universities, teachers, and students.

Novelty/Originality: In this research, the model of National Self-Consciousness of Students in Higher Educational Studies in the Republic of Tatarstan by Means of Humanitarian Disciplines is presented in a comprehensive and complete manner.
BLENDED LEARNING IN UNIVERSITY EDUCATION
Authors: Abrosimova Galina , Kondrateva Irina , Voronina Ekaterina , Plotnikova Nailya
Published: November 2019

Purpose of the study: The article brings forward the definition, based on the analysis of both domestic and foreign scientists’ views; structure components of blended learning with account taken of university-specific character.

Methodology: Blended learning process is presented as a model consisting of 9 successive stages, each of them represents a logical sequence of measures ensuring the dynamics of system development.

Results: The developed by the author model result in the recommendation to proceed to “blended learning” which is conceptually based on the constructive potential of a teacher, on searching ways of its building on the basis of communicative, person-centered and interactive approaches, increasing organizational changeability of the educational environment.

Applications of this study: This research can be used for the universities, teachers, and students.

Novelty/Originality of this study: In this research, the model of the Blended Learning in University Education is presented in a comprehensive and complete manner.
RUSSIA IN THE FOCUS OF THE EXISTENCE AND THE DUE
Authors: Olegovna Khazieva Nataliia , Khatypovich Khaziev Aklim , Vladimirovna Klyushina Elena , Nikolaevich Stepanenko German , Faritovna Stepanenko Ravya
Published: November 2019

Purpose: In the center of work is the philosophy of history of Russia for the last hundred years of its existence through a prism real and due. Proceeding from a recognized thesis that it is natural to eat development of society - historical process authors focused the attention on modeling social development.

Methodology: Methods of our analysis of the Soviet and Post-Soviet society will be based on documents of a political character, and, first of all, on the attestations of eyewitnesses reflecting daily occurrence language as in it the life of the person and society affects more adequately.

Result: In the early nineties the last century the project of Post-Soviet Russia as a synonym of "the highway of a human civilization" began to be embodied. However, over time and it appeared under criticism fire as did not consider the identity of Russia. There was a requirement of the embodiment new due where the dialectics of the general, special and single is the leader.

Applications: This research can be used for the universities, teachers, and students.

Novelty/Originality: In this research, the model of Russia in the Focus of the Existence and the DUE is presented in a comprehensive and complete manner.
Some Considerations and a Benchmark Related to the CNF Property of the Koczy-Hirota Fuzzy Rule Interpolation
Authors: Alzubi Maen , Kovacs Szilveszter
Published: November 2019

The goal of this paper is twofold. Once to highlight some basic problematic properties of the KH Fuzzy Rule Interpolation through examples, secondly to set up a brief Benchmark set of Examples, which is suitable for testing other Fuzzy Rule Interpolation (FRI) methods against these ill conditions. Fuzzy Rule Interpolation methods were originally proposed to handle the situation of missing fuzzy rules (sparse rule-bases) and to reduce the decision complexity. Fuzzy Rule Interpolation is an important technique for implementing inference with sparse fuzzy rule-bases. Even if a given observation has no overlap with the antecedent of any rule from the rule-base, FRI may still conclude a conclusion. The first FRI method was the Koczy and Hirota proposed "Linear Interpolation", which was later renamed to "KH Fuzzy Interpolation" by the followers. There are several conditions and criteria have been suggested for unifying the common requirements an FRI methods have to satisfy. One of the most common one is the demand for a convex and normal fuzzy (CNF) conclusion, if all the rule antecedents and consequents are CNF sets. The KH FRI is the one, which cannot fulfill this condition. This paper is focusing on the conditions, where the KH FRI fails the demand for the CNF conclusion. By setting up some CNF rule examples, the paper also defines a Benchmark, in which other FRI methods can be tested if they can produce CNF conclusion where the KH FRI fails.
Development of PSO for tracking Maximum Power Point of Photovoltaic Systems
Authors: Pham Cong Thanh , Nhu Khai Hoan , Dong Van Huong , Le Thi Huong , Hoang Thi Thom
Published: November 2019

For a photovoltaic system, the relationship of the output voltage and power is usually non-linear, so it is essential to equip a MPPT controller in PV systems. Furthermore, the hotspot problem is a common phenomenon, resulting from the PV system operating under PSC. Partial shading not only damages the PV cells, but also makes it difficult to find the global MPP in the characteristic curves of P-V. The paper proposes a novel version of PSO, namely PPSO in order to detect the global peak among the multiple peaks, known as the true maximum energy from PV panel. For this, the PPSO algorithm makes the velocity of each particle be perturbed once the particles are struck into a local minima state in order to find the best optimum solution in the MPPT problem. The perturbation in the velocity vector of each particle not only helps them tracking the MPP accurately under the changing environmental conditions, such as large fluctuations of insolation and temperature like PSC; but also removes the steady-state oscillation. The proposed approach has been tested on a MPPT system, which controls a dc-dc boost converter connected in series with a resistive load. Moreover, the obtained results are compared to those obtained without any MPPT controller to prove the efficiency of the suggested method. In addition, this novel version gives the highest accuracy of tracking the optimum power in the least iteration number as compared to the conventional PSO.
Relationship between Ottoman and Albanian Culture as an Intercultural Example of Interaction
Authors: Özkul Osman , Zullufi Nazim
Published: November 2019

Islam and Ottoman cultures have had a significant impact on the Albanian culture from the 15th century to the present. Islam has also been a shield that protects Albanian culture from Slavic and Greek assimilations. Therefore, the Islamic culture has had a very strong influence on the components that formed Albanians' social structure. It is possible to see the effects of Islamic culture on Albanians' life styles, family cultures, death and marriage rituals, economic lives, legal relations and all mentality structures and the system of values ​​that constitute the society. It was not difficult to adapt to the Albanian culture especially for the Ottoman interpretation of Islam because these two cultures have been built similarly on the old Mediterranean cultural basin. It is possible to find many common values ​​between the two cultures. For example, the values ​​including tolerance, indulgence, freedom, and, most importantly, being against discrimination are the elements that made these two cultures closer and united to each other. It is sufficient to look at the history in order to understand how tolerant Albanians are about religion. They have been able to live together with three different religions in high tolerance for centuries. The level of tolerance is such that there are individuals of different religions in a tribe or even in a family. The Islamized Albanians can also maintain their traditions, customs and authentic lifestyles along with the Islamic culture.
Mixgenetic concept of of oil and gas fields formation in basement and sedimentary cover on the shelf of South Vietnam
Authors: Utoplennikov Vladimir K. , Drabkina Anastasia D.
Published: November 2019

According to the geodynamic model of oil and gas formation, the most favorable conditions for the oil and gas fields are formed in the mobile zones of the earth’s crust, especially in areas of active continental margins, characterized by high seismicity, the presence of deep faults, the development of subduction and riftogenic processes. Therefore, it is logical that most of the world’s oil and gas deposits are concentrated in rifts or in the vicinity of paleo- and modern subduction zones.
The study of the unique oil deposits in the granite basement of the White Tiger field, using data from other fields in the world, allows concluding that the formation of oil deposits in the basement can occur not only due to the resources of adjacent oil and gas deposits.
Taking into account modern geodynamic ideas, in the context of the Earth’s internal geospheres, at least three oil generation zones can be distinguished: mantle-asthenospheric abiogenic synthesis; subduction-dissipative biomineral synthesis; stratospheric-biogenic synthesis.
Obviously, all these three zones, as a single open system for the generation of hydrocarbons, will be interconnected only in conditions of deep faults, active continental margins and other parts of the Earth’s crust. This suggests that there are deep generation zones, which are currently fueling the developed fields.
Replenishment of oil deposits from the position of a new concept of oil and gas formation
Authors: Muslimov Renat Kh. , Plotnikova Irina N.
Published: November 2019

The article is devoted to the problem of replenishing of oil reserves and considers it (the problem) in the aspect of deep degassing of the Earth. Based on an analysis of the results of a long-term study of the Precambrian crystalline basement in the territory of Tatarstan and adjacent areas, a number of new criteria are formulated that allow us to identify the processes of deep degassing of the Earth within the studied region.
The article provides a brief overview of current views on the problem of replenishing oil reserves, considers options for possible sources and the mechanism of replenishment of hydrocarbons in the developed deposits. The arguments in favor of the modern process of deep degassing within the South Tatar arch and adjacent territories are examined, which are unequivocally confirmed by: the dynamics of the hydrochemical parameters of the deep waters of the crystalline basement obtained in the monitoring mode at five deep wells; uneven heat flux and its anomalies, recorded according to many years of research under the guidance of N.N. Khristoforova. The degassing processes are also confirmed by the dynamics of gas saturation of decompressed zones of the crystalline basement recorded in well 20009-Novoelkhovskaya, the dynamics of gas saturation of oil of the sedimentary cover and the composition of the gas dissolved in it, identified by oil studies in piezometric wells located in different areas of the Romashkinskoye field; the seismicity of the territory of Tatarstan, as well as its neotectonic activity. As criteria proving the existence of a process of replenishing the reserves of the developed oil fields of the South Tatar Arch, the features of the deep structure of the earth’s crust according to seismic data, as well as the results of geochemical studies of oils are considered.
China en el siglo XXI, el despertar de un gigante
Authors: Chen Lan
Published: November 2019

El libro China en el Siglo XXI, el Despertar de un Gigante cuyo autor es el Dr. Sergio Rodríguez Gelfenstein, explora la lógica del sistema político y la actuación de los chinos a través del análisis de su historia y pensamiento filosófico. Con la utilización de referentes teóricos del propio gigante asiático, el autor llega a la conclusión de que la República Popular China ha desarrollado un exitoso experimento propio tanto en los asuntos internos como externos, sustentado en peculiaridades generadas a lo largo de su transcurrir milenario, el cual se ha ido adaptando a las características y las condiciones de la modernidad.
Acute Cellular Rejection in Paediatric Liver Transplants: Does a Living Donor Ameliorate the Risk of Rejection in Our Patients? A Retrospective Review at Wits Donald Gordon Medical Centre, South Africa
Authors: Strong Jessica Katharine , Gaylard Petra , Maher Heather , Botha Jean
Published: November 2019

Background: Despite the enlarging pool of paediatric liver transplants (LT), there is a paucity of data-detailing risk factors for acute cellular rejection (ACR).

Objective: To identify risk factors associated with ACR.

Method: We reviewed the data of 98 paediatric patients at Wits Donald Gordon Medical Centre who underwent LT between 2015 and 2018, and subsequent histologically determined ACR.

Results: Of the 98 patients who received a LT, 52% of donors were deceased donors and 48% were living donors. Twenty-two per cent of the patients were diagnosed with ACR during the first 90 days post LT. Sixty-eight per cent of living donor liver transplants were in the shortest (less than 2.5 h) cold ischaemic time (CIT) tertile, while 0% of deceased donor organs were transplanted prior to 2.5 h. We identified decreased CIT and living donor status as factors, both closely related to each other and associated with a decreased risk of ACR.

Conclusion: CIT is associated with a decreased risk of ACR. Living donor LT is associated with a decreased CIT and as a result a less inflammatory milieu in the early post LT period. Further research should be conducted, with particular reference to a decreased risk of ACR in living donor paediatric LT, in order to better inform immunosuppressive therapeutic regimens.
Murder in the Cathedral: Antibodies and the Limits of Transplantation
Authors: Davies Malcolm
Published: November 2019

Although transplantation is the optimal therapy for end-stage renal disease, long-term survival of kidney allografts remains elusive. Antibody-mediated rejection has been implicated as a major factor in late period graft loss. The refractory nature of late period antibody-mediated rejection is the evidence of an important immunological process with implications for other solid organ transplants and for other diseases. This review details advances in the understanding of late period antibody-mediated rejection in the context of local experience.
Christ’s Supremacy: Colossians 1:15-20 and Its Implication in Education
Authors: Han Chandra
Published: November 2019

Supremacy of Christ in Col. 1:15-20 is essential to Christian faith. Many attempts have been made to examine this passage and mostly from the theological point of view. The aim of this article is to reexamine this passage and propose an analysis from the perspective of Christian education (with the implications) by firstly exegeting the passage in Colossian’s context. The exegesis begins with providing the translation form the Greek text, proposing the structure followed by demonstrating the critical issue in each section of the structure, and finally summarizing the principles. The next step is to demonstrate the analysis from the perspective of Christian education on every section in the structure, followed by the significance of this passage in Christian education.
Reflexões acerca do panorama de consumo de álcool e/ou outras drogas entre estudantes universitários
Authors: Gonçalves Jamila Souza , Leite Fava Silvana Maria Coelho , Alves Andrea Cristina , Dázio Eliza Maria Resende
Published: November 2019

Objetivo: Refletir acerca do panorama de consumo de álcool e/ou outras drogas entre estudantes universitários e suas implicações na vida acadêmica e pessoal desses estudantes. Método: Trata-se de uma reflexão teórica, construída com base na leitura de estudos científicos atuais que atendem à seguinte questão norteadora: Qual o panorama de consumo de álcool e/ou outras drogas entre estudantes universitários? Os artigos analisados levaram à concretização da seguinte categoria: “Panorama de consumo de álcool e/ou outras drogas entre estudantes universitários. Resultados: Verificou-se que o álcool foi a droga de maior consumo entre os estudantes. Embora exista uma preocupação entre os pesquisadores em relação ao uso de álcool e/ou outras drogas entre

universitários ficou evidente que o início do consumo dessas substâncias entre universitários não se encontra, necessariamente, vinculado ao ingresso na universidade. Conclusão: Constatou-se o uso cada vez mais excessivo de substâncias psicoativas entre os jovens universitários, sendo preciso que a universidade cumpra seu papel, criando políticas efetivas para o enfrentamento das questões referentes ao uso de álcool e/ou outras drogas, com vistas às ações de prevenção e de tratamento, que contemplem as reais necessidades dos jovens universitários, sem nenhum tipo de discriminação.
Quedas entre crianças e adolescentes internados em hospitais: revisão integrativa de literatura
Authors: Vieira Gisele Lacerda Chaves , Campos Isa Maria Lima , Fernandes Bárbara Sgarbi Morgan , Ladeira Anne Gadelha , Pimenta Emmanuelle Ferreira
Published: November 2019

Objetivo: investigar as taxas, as características, os fatores associados e as medidas preventivas relacionadas às quedas entre crianças e adolescentes em hospitais. Método: revisão integrativa de literatura realizada nas bases Scientific Electronic Library Online, Biblioteca Virtual em Saúde, National Library of Medicine e Google Scholar. Resultados: dez estudos atenderam aos critérios estabelecidos. As taxas variaram de 0.6 a 1.7 quedas por 1000 pacientes/dia. Grande parte das quedas ocorrem entre crianças do sexo masculino; com idade inferior a 9 anos. A maioria desses incidentes ocorrem na presença de um adulto. São fatores de risco para a ocorrência de quedas: idade da criança (p
Empatia em saúde: revisão integrativa
Authors: Mufato Leandro Felipe , Gaíva Maria Aparecida Munhoz
Published: November 2019

Objetivo: Analisar as publicações de pesquisas disponíveis na literatura sobre empatia no cuidado em saúde. Método: Revisão integrativa com busca de estudos primários realizada nas bases de dados LILACS, PSYCINFO, WEB OF SCIENCE, BDENF, MEDLINE e CINAHL, sem restrição de período e idioma. Resultado: A análise de 33 estudos primários mostra publicações de 1968 a 2016, originárias de diferentes regiões do mundo. Há predomínio da abordagem quantitativa com o uso de diferentes escalas psicométricas autoaplicáveis para mensurar os níveis de empatia de profissionais da saúde, estudantes ou pacientes. Há diversidade nas populações pesquisadas, locais de estudo e falta consenso entre os autores sobre como a empatia se desenvolve, perpassando explicações pelos campos da cognição, emoção e atividade neuromotora. Conclusão: O debate sobre a empatia está em pleno desenvolvimento, especialmente, quando se observam as diferentes explicações para sua ocorrência. A empatia é um forte constructo capaz de contribuir para pesquisas sobre a relação profissional-paciente.
Esperança de famílias que convivem com comportamento aditivo por tempo prolongado
Authors: Elvira Indianatha De Kássia Santana , Dos Reis Lúcia Margarete , Gavioli Aroldo , Marcon Sonia Silva , De Oliveira Magda Lúcia Félix
Published: November 2019

Objetivo: Identificar a esperança de famílias que convivem por tempo prolongado com o comportamento aditivo de um de seus membros. Métodos: Estudo transversal com familiares de 29 indivíduos internados com trauma físico associado à intoxicação por drogas de abuso, considerados eventos sentinela em um programa de vigilância epidemiológica das repercussões do uso de drogas em famílias. Foram utilizados um roteiro semiestruturado de entrevista e a Escala de Hopefulness–hopelessness. O teste de MannWhitney foi empregado para se verificar associações estatísticas. Resultados: Os usuários tinham, em média, idade de 40,1 anos e tempo médio de uso de drogas de 20,8 anos. O escore médio de esperança dos familiares foi de 28,81(± 2,83). A idade, o tempo de uso e o poliuso de drogas pelos usuários foram estatisticamente associados aos menores níveis de esperança, enquanto a prática religiosa, pelos familiares, foi estatisticamente associada a maiores níveis de esperança. Conclusão: Observou-se um escore médio de esperança baixo, indicando a necessidade de intervenção sobre esse sentimento nas famílias estudadas.
THE INFLUENCE OF COMPLEX THERAPY ON THE INFLAMMATORY MARKERS OF PATIENTS WITH SECONDARY OSTEOARTHRITIS
Authors: Starodubtseva I. A.
Published: November 2019

The aim of the study is to evaluate the efficacy of complex therapy of secondary osteoarthritis in patients with rheumatoid arthritis with the use of inhibitor of interleukin-1, including the dynamics of inflammatory markers.

Materials and methods: 248 patients with secondary osteoarthritis in rheumatoid arthritis were involved in the trial. The participants were divided into 4 groups: patients of group I took inhibitor of interleukin-1 (diacerein) in combination with laser therapy and methotrexate; inhibitor of interleukin-1 in complex with methotrexate took patients from group II; group 3 — laser therapy + methotrexate and patients of group IV took only methotrexate. The efficacy of therapy we estimated in 6 months.

Results: The constructed model surfaces indicated the decreased levels of IL-1, COMP and DAS 28 in group 1 till 6,68±0,37 pg/ml (p<0,001), 16,92±0,8 ng/ml х 10² (p<0,001) и 2,06±1,19 (p<0,05) accordingly in comparison with groups III and IV. Also the model surfaces revealed the interdependency of all these indicators. The control group (IV) reacted to the treatment by decreasing the indicators as well. However, the dynamics of the changes was significantly less. In patients of groups I and II the levels of ESR and CRP decreased to 13,95±0,52* (*p<0,001) and 10,97±0,43* (*p<0,001); 16,53±0,63* (*p<0,001) and 12,81±0,77* (*p<0,001) accordingly.

Conclusions: In comparison analysis we noted statistical significant advantages (p<0,01) of the use of diacerein with methotrexate regarding the dynamic of IL-1 and COMP, ESR, CRP in patient’s serum, which is accompanied by the reduction of basic disease activity on DAS 28.
Relationship between empathy dimension and customer satisfaction in the insurance industry in Kenya
Authors: Chege Catherine Njoki , Wanjau Kenneth , Nkirina Severina
Published: November 2019

The Insurance industry is essential to the economic course of every nation attaining sustainable growth and prosperity. However, the industry continues to experience a marginal growth of 2.5% compared to the global real term growth of 4%. This study analyzed the relationship between employee empathy and customer satisfaction in the Kenyan insurance industry. The study was guided by the causal research design. The study applied the linear mixed-effect models of structural equation modeling (SEM) considering the multi-level structure of the data collected. The study concluded that a client who perceives empathy from his/ her insurer’s employees is bound to have higher satisfaction than a customer who does not perceive empathy from their insurer. Employee empathy however, does not significantly affect the variations of customer satisfaction between the insurance companies.
IoT Privacy Preservation Using Blockchain
Authors: Patel Chintan
Published: November 2019

Internet of things security will be a big challenge for the enterprises working behind the build-up of the internet of things, and it’s application. With IoT, another buzzword is blockchain-based cryptocurrency bitcoin. Blockchain technology has proven itself as one of the most secured existing technology. In this paper, we have discussed the signiﬁcant challenges that will come up in identity management due to the heterogeneity of devices. We have proposed a solution for privacy preservation using secure identity management and possible communication methodology by using public key-based cryptography used in the blockchain. We have taken the ecosystem of smart home management and smart health management. At last, we have concluded with the discussion of futuristic applications of blockchain in other applications of the internet of things.
PI3K in Stemness Regulation: From Development to Cancer
Authors: Madsen Ralitsa
Published: November 2019

The PI3K/AKT pathway is a key target in oncology where most efforts are focussed on phenotypes such as cell proliferation and survival. Comparatively little attention has been paid to PI3K in stemness regulation, despite the emerging link between acquisition of stem cell-like features and therapeutic failure in cancer. The aim of this review is to summarise current known and unknowns of PI3K-dependent stemness regulation, by integrating knowledge from the fields of developmental, signalling and cancer biology. Particular attention is given to the role of the PI3K pathway in pluripotent stem cells (PSCs) and the emerging parallels to dedifferentiated cancer cells with stem cell-like features. Compelling evidence suggests that PI3K/AKT signalling forms part of a ‘core molecular stemness programme’ in both mouse and human PSCs. In cancer, the oncogenic PIK3CAH1047R variant causes constitutive activation of the PI3K pathway and has recently been linked to increased stemness in a dose-dependent manner, similar to observations in mouse PSCs with heterozygous versus homozygous Pten loss. There is also evidence that the stemness phenotype may become ‘locked’ and thus independent of the original PI3K activation, posing limitations for the success of PI3K monotherapy in cancer.Ongoing therapeutic developments for PI3K-associated cancers may therefore benefit from a better understanding of the pathway’s two-layered and highly context-dependent regulation of cell growth versus stemness.
Ulmus Parvifolia Accelerate Skin Wound Healing by Regulating the Expression of MMPs and TGF-β
Authors: Kang Min Cheol , Yumnam Silvia , Park Woo Sung , So Hae Min , Kim Ki Hyun , Shin Meong Cheol , Ahn Mi-Jeong , Kim Sun Yeou
Published: November 2019

Ulmus species have been widely used in Korean folk medicine because of their anti-inflammatory and antimicrobial properties. We intended to investigate the wound healing effect of the powder of Ulmus parvifolia (UP) root bark in a mouse wound healing model. We also determined the mechanisms of effects of Ulmus parvifolia (UP) in skin and skin wound healing effect using keratinocyte model. in vivo experiments showed that the wound lesions in the mice decreased by U. parvifolia with 200 mesh size of root bark powder and significantly reduced by treatment with UP, compared with those treated with U. macrocarpa (UM). Results from in vitro experiments also revealed that UP extract promoted the migration of human skin keratinocytes. UP powder treatment upregulated the expression of the matrix metalloproteinase-2 and -9 protein and significantly increased transforming growth factor (TGF)-β levels. We confirmed that topical administration of the bark powder of exerted a significant effect on skin wound healing by upregulating the expression of MMP and transforming growth factor-β. TGF-β In, Our study suggests that U. parvifolia may be a potential candidate for skin wound healing including epidermal skin rejuvernation.
Geo-Mapping of Areas Vulnerable to Ala-River Basin Flood Disaster Risk in Akure, Ondo State, Nigeria
Authors: Bakare Gani Olalekan , Omosulu Samuel Bamikole , Famutimi John Taiwo
Published: November 2019

Flood is identified as one of the major disasters in the world; it destroys both human and properties across the world, where lives are lost, properties, public infrastructure, farmlands and agricultural produce with farm crops carted away as a result of flood disaster. Studies revealed that the flood in itself is not the danger, but the level of human vulnerability to flooding disaster risk, which enhances its destructive capabilities. However, based on the challenges poses by flood disaster risk, this research identifies Ala river in Akure as a potential cause of flood, considering its location and other human activities around the river. Therefore, the research used Ala-river a case study to identify and mapped out areas susceptible to flood disaster risk. The research made use of both literature review and conducted goe-data gathering with the application GIS-computer database to retrieve georeferencing relevant data from the fieldwork in the study area of Ala-river basin to mapped out locations vulnerable to achieve the research aim. The research adopted a Geo-mapping of the vulnerable area to Ala-River basin using arc-GIS tool in combination with other software such as IKONAS and OLI (Operation Land Imager) for the production of the study area imagery, ER-ITERIM was used for the collection of rainfall data and FAO was applied for digital soil mapping. These applications produced; the land use/land cover map, digital elevation map, buffer map using 30 meters setback, annual rainfall map, soil types map, vulnerability map and soil textural table for the study area. Analysis of the produced and generated maps shows 316 buildings vulnerability to flood disaster risk; the soil texture and types, and alternative use to which the soil types can be useful. The research recommends that demolition of the identified 316 buildings prone to flood disaster and compliance of building construction to 30 meters setback by developers. Others are the conversion of the future land setback for urban agricultural purposes and preservation of water retention areas for agricultural activities during the dry season among others. The study concludes that relevant government agencies in the State and in particular in Akure South Local Government should ensure prompt compliance and implementation of the recommendations to avoid potential flood disaster risks.
Catalytic Combustion of Dimethyl Disulfide on Bimetallic Supported Catalysts Prepared by the Wet-Impregnation Method
Authors: Gao Junan , Gao Song , Wei Jun , Zhao Hong , Zhang Jie
Published: November 2019

In this paper, the catalytic combustion of DMDS (dimethyl disulfide, CH3SSCH3) over bimetallic supported catalysts were investigated. It was confirmed that Cu/γ-Al2O3-CeO2 showed best catalytic performance among the five single-metal catalysts. Furthermore, six different metals were separately added into Cu/γ-Al2O3-CeO2 to investigate the promoting effect. The experiments revealed Pt as the most effective promoter and the the best catalytic performance was achieved as the adding amount of 0.3 wt%. The characterization results indicated that high activity and resistance to sulfur poisoning of Cu-Pt/γ-Al2O3-CeO2 could be attributed to the synergistic effect between Cu and Pt.
Curcumin Derivative C212 Inhibits Hsp90 and Eliminates Both Quiescent and Growing Leukemia Cells
Authors: Liu Bi , Shen Yunzhu , Huang Huafang , Della Croce Kimiko , Wu Min , Fan Yingjuan , Liu Yang , Xu Jianhua , Yao Guang
Published: November 2019

Relapsed leukemia following initial therapeutic response and remission is difficult to treat and causes high patient mortality. Leukemia relapse is due to residual quiescent leukemia cells that escape conventional therapies and later reemerge. Eliminating not only growing but quiescent leukemia cells is critical to effectively treating leukemia and preventing its recurrence. Such therapeutic agents, however, are lacking in the clinic. Here we report that a 4-arylmethyl derivative of the natural anticancer compound curcumin demonstrates a dual effect in eliminating both growing and quiescent leukemia cells. This curcumin derivative, C212, on the one hand, inhibits growing leukemia cells at a higher efficacy than curcumin by inducing apoptosis and cell cycle arrest; it, on the other hand, kills quiescent leukemia cells that are resistant to conventional chemotherapy drugs. Furthermore, C212 drives leukemia cells into and kills them at deep quiescence, avoiding the potential risk associated with awaking therapy-resistant subpopulation of quiescent leukemia cells. Lastly, we show that C212 induces apoptosis and drives cells into deep dormancy at least partially by binding to and inhibiting Hsp90, leading to client protein degradation and protein aggregation. Further elucidating the molecular mechanisms underlying the dual function of C212 in eliminating both growing and quiescent leukemia cells will aid the development of novel therapies against leukemia relapse.
Potency of Cockroaches (Periplaneta americana and Blattella germanica) as Vector of Salmonellosis on Ships in Baubau Port
Authors: Supryatno Adi , Murtini Sri , Hadi Upik Kesumawati
Published: November 2019

ABSTRACT Cockroaches are insects that act as mechanical vectors of pathogenic agents to humans such as Salmonella sp. The aim of this study was to identify the presence of Salmonella sp. in cockroach bodies on cargo and passenger ships. This research was conducted at Baubau Port from October to December 2017. A total of 24 ships were examined consisting of 12 passenger ships and 12 cargo ships. Cockroaches were collected from rooms inside each ship namely galley, bridge, deck and bathroom. A total of 3 196 cockroaches caught consisting of Periplaneta americana (69.50%), Blattella germanica (29.60%), Periplaneta brunnea (0.66%), Pseudophorapsis sp. (0.03%), Pycnoscelus surinamensis (0.03%), Periplaneta australasiae (0.03%), and Neuphoeta cinerea (0.03%). The presence of Salmonella sp. were examined for cockroach species with a large number of population, namely Periplaneta americana and Blattella germanica. A total of 95.3% of the 42 cockroaches examined in the laboratory contained Salmonella sp.. Based on this research it can be concluded that the cockroaches collected from the ships leaning at Baubau Port can serve as a vector of salmonellosis for both ship crew and passengers. Keywords: Cockroaches, Ships, Salmonella sp, Salmonellosis
Bats Oxidative Stress Defense
Authors: Hanadhita Desrayni , Satyaningtijas Aryani Sismin , Agungpriyono Srihadi
Published: November 2019

Antioxidants and free radicals have long been known to be the main factors in the occurrence of degenerative diseases. Various studies related to antioxidants and free radicals which have implications for oxidative stress have increased in the last decade. Knowledge of stress oxidative physiology in various animals help in understanding the pathophysiology of diseases associated with oxidative stress. Bats are claimed to be the best known animals in term of survival compared to other mammals. Bats are reported to produce low reactive oxygen species (ROS) but high endogenous antioxidants that can prevent oxidative stress. Bats high defense against oxidative stress has implications for their extreme longevity, the role as a reservoir of viruses, and the potential as experimental animals.
The Anatomy of Asian Palm Civet (Paradoxurus hermaphroditus) Brain in Timor Island
Authors: Amalo Filphin Adolfin , Selan Yulfia Nellymalik , Widi Antin Yeftanti Nugrahening , Rimu Andry Ndula
Published: November 2019

Asian palm civet (Paradoxurus hermaphroditus) is native to some Asian regions, include Indonesia. Despite its wide spreading in those areas, study in regards to its anatomy is very few. This study is aimed to unveil the anatomy of Asian plam civet brain in Timor island. This study was performed in three Asian palm civets. The palm civets were anesthesized and humanely euthanazied using perfusion technique, and macroscopically observed for their brains anatomy.  Results showed Asian palm civet consisted of three main parts which were cerebrum, cerebellum, and brain stem. Compared to brain of dog, sulci and gyri of the Asian palm civet is simpler, with paraflocculus lobes were merely located in dorsal and ventral parts of the brain. However, the vermis was more similar to dogs, and more developed compare to Reusettussp (Javanese codot). This suggests that the anatomical difference is a result of the different behavior, which are nocturnal animal and live on trees.
Composite and diachronous stratigraphic surfaces in low-gradient, transitional settings: The J-3 “unconformity” and the Curtis Formation, east-central Utah, U.S.A.
Authors: Zuchuat Valentin , Midtkandal Ivar , Poyatos-Moré Miquel , Da Costa Sigrid , Brooks Hannah Louise , Halvorsen Kristine , Cote Nathan , Sundal Anja , Braathen Alvar
Published: November 2019

Unconformities, by definition, correspond to erosional or nondepositional surfaces, which separate older strata below, from younger rocks above, encapsulating significant time gaps. However, recent studies have highlighted the composite nature of some unconformities, as well as their heterochronous and diachronous character, which challenge the use of such a definition in a four-dimensional dynamic environment. The J-3 Unconformity, separating the Middle Jurassic Entrada Sandstone from the Upper Jurassic Curtis Formation (and laterally equivalent units) in east-central Utah (USA), is laterally variable, generated by either erosion-related processes such as eolian deflation, and water-induced erosion, or by deformational processes. The J-3 Unconformity is a composite surface, formed by numerous processes that interacted and overlapped spatially and temporally. This study therefore demonstrates the heterochronous, diachronous, and non-unique nature of this surface interpreted as unconformity, where one process can be represented by varying expressions in the stratigraphic record, and conversely many processes may result in the same stratigraphic expression.
Experimental Study of Flooding both Low Salinity Water and Foam in Sandstone Reservoirs Bearing Heavy Crude Oil
Authors: Al-Saedi Hasan Naeem , Al-Jaberi Soura Kassim , Al-Bazzaz Waleed , Flori Ralph Emil
Published: November 2019

Many studies have been performed to increase oil recovery by using low salinity (LS) water flooding in the tertiary recovery mode due to its impact in altering the rock wettability towards being more water-wet, resulting in improved oil recovery. Foam was also utilized to enhance oil recovery due to its ability to increase residual oil mobility and sweep efficiency. In this study, we combine both LS water and foam to utilize the benefits of both EOR techniques.

To evaluate the combination EOR techniques, Berea sandstone cores were allotted for core-flooding experiments. The core-flooding results showed that an increased heavy oil recovery was obtained by injecting foam and lowering water salinity. The contact angle measurements agreed with the core-flooding observations.
Complete genome sequences of Streptomyces spp. isolated from disease-suppressive soils
Authors: Heinsch Stephen C , Hsu Suzie , Otto-Hanson Lindsey , Kinkel Linda , Smanski Michael
Published: November 2019

Bacteria within the genus Streptomyces remain a major source of new natural product discovery and as soil inoculants in agriculture where they promote plant growth and protect from disease. Recently, Streptomyces spp. have been implicated as important members of naturally disease-suppressive soils. To shine more light on the ecology and evolution of disease-suppressive microbial communities, we have sequenced the genome of three Streptomyces strains isolated from disease-suppressive soils and compared them to previously sequenced isolates. Strains selected for sequencing had previously showed strong phenotypes in competition or signaling assays. Results Here we present the de novo sequencing of three strains of the genus Streptomyces isolated from disease-suppressive soils to produce high-quality complete genomes. Streptomyces sp. GS93-23, Streptomyces sp. 3211-3, and Streptomyces sp. S3-4 were found to have linear chromosomes of 8.24 Mb, 8.23 Mb, and greater than 7.5 Mb, respectively. In addition, two of the strains were found to have large, linear plasmids. Each strain harbors between 26 and 38 natural product biosynthetic gene clusters, on par with previously sequenced Streptomyces spp.. We compared these newly-sequenced genomes with those of previously sequenced organisms. We see substantial natural product biosynthetic diversity between closely related strains, with the gain/loss of episomal DNA elements being a primary driver of genome evolution. Conclusions Long read sequencing data facilitates large contig assembly for high-GC Streptomyces genomes. While the sample number is too small for a definitive conclusion, we do not see evidence that disease suppressive soil isolates are particularly privileged in terms of numbers of BGCs. The strong sequence similarity between GS93-23 and previously isolated Streptomyces lydicus suggests that species recruitment may contribute to the evolution of disease-suppressive microbial communities.
A MYB-related Transcription Factor from Sheepgrass, LcMYB2, Promotes Seed Germination and Root Growth under Drought Stress
Authors: Zhao Pincang , Hou Shenglin , guo xiufang , Jia Junting , Yang Weiguang , Liu Zhujiang , Chen Shuangyan , Li Xiaoxia , Qi Dongmei , Liu Gongshe , Cheng Liqin
Published: November 2019

Background Drought is one of the most serious factors limiting plant growth and production. Sheepgrass can adapt well to various adverse conditions, including drought. However, during germination, sheepgrass young seedlings are sensitive to these adverse conditions. Therefore, the adaptability of seedlings is very important for plant survival, especially in plants that inhabit grasslands or the construction of artificial grassland. Results In this study, we found a sheepgrass MYB-related transcription factor, LcMYB2 that is up-regulated by drought stress and returns to a basal level after rewatering. The expression of LcMYB2 was mainly induced by osmotic stress and was localized to the nucleus. Furthermore, we demonstrate that LcMYB2 promoted seed germination and root growth under drought and ABA treatments. Additionally, we confirmed that LcMYB2 can regulate LcDREB2 expression in sheepgrass by binding to its promoter, and it activates the expression of the osmotic stress marker genes AtDREB2A, AtLEA14 and AtP5CS1 by directly binding to their promoters in transgenic Arabidopsis. Conclusions Based on these results, we propose that LcMYB2 improves plant drought stress tolerance by increasing the accumulation of osmoprotectants and promoting root growth. Therefore, LcMYB2 plays pivotal roles in plant responses to drought stress and is an important candidate for genetic manipulation to create drought-resistant crops, especially during seed germination.
Understanding the Healthcare Experiences and Needs of African Immigrants in the United States: A Scoping Review
Authors: Omenka Ogbonnaya Isaac , Watson Dennis P. , Hendrie Hugh C.
Published: November 2019

Background: Africans immigrants in the United States are the least-studied immigrant group, despite the research and policy efforts to address health disparities within immigrant communities. Although their healthcare experiences and needs are unique, they are often included in the “black” category, along with other phenotypically-similar groups. This process makes utilizing research data to make critical healthcare decisions specifically targeting African immigrants, difficult. The purpose of this Scoping Review was to examine extant information about African immigrant health in the U.S., in order to develop lines of inquiry using the identified knowledge-gaps. Methods: Literature published in the English language between 1980 and 2016 were reviewed in five stages: (1) identification of the question and (b) relevant studies, (c) screening, (d) data extraction and synthesis, and (e) results. Databases used included EBSCO, ProQuest, PubMed, and Google Scholar (hand-search). The articles were reviewed according to title and abstract, and studies deemed relevant were reviewed as full-text articles. Data was extracted from the selected articles using the inductive approach, which was based on the comprehensive reading and interpretive analysis of the organically emerging themes. Finally, the results from the selected articles were presented in a narrative format. Results: Culture, religion, and spirituality were identified as intertwined key contributors to the healthcare experiences of African immigrants. In addition, lack of culturally-competent healthcare, distrust, and complexity, of the U.S. health system, and the exorbitant cost of care, were identified as major healthcare access barriers. Conclusion: Knowledge about African immigrant health in the U.S. is scarce, with available literature mainly focusing on databases, which make it difficult to identify African immigrants. To our knowledge, this is the first Scoping Review pertaining to the healthcare experiences and needs of African immigrants in the U.S.