bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of White Potatoes on Subjective Appetite, Food Intake, and Glycemic Response in Healthy Older Adults
Authors: Bellissimo Nick , Almalraj Robena , Lee Jenn , Brett Neil R. , O. Totosy de Zepetnek Julia , Proteau Sarah , Rousseau Dérick
Published: August 2024

The objective of this study was to determine the effect of white potato cooking methods on subjective appetite, short-term food intake (FI), and glycemic response in healthy older adults. Using a within-subject, repeated-measures design, 20 participants (age: 70.4 ± 0.6 y) completed, in random order, five treatment conditions: three potato treatments (baked potatoes, mashed potatoes, and French fries), an isocaloric control treatment (white bread), or a fasting condition (meal skipping). Subjective appetite and glycemic response were measured for 120 min using visual analogue scales and capillary blood samples, respectively. Lunch FI was measured with an ad libitum pizza meal at 120 min. Change from baseline subjective appetite (p < 0.001) and lunch FI (p < 0.001) were lower after all test treatments compared with meal skipping (p < 0.001), but did not differ among test treatments. Cumulative FI (test treatment + lunch FI) did not differ among treatment conditions. Blood glucose concentrations were higher after all test treatments compared with meal skipping (p < 0.001), but were not different from each other. In healthy older adults, white potatoes suppressed subjective appetite and lunch FI compared with meal skipping, suggesting white potatoes do not bypass regulatory control mechanisms of FI. 
Phylogeny of Weinmannia (Cunoniaceae) reveals the Contribution of the Southern Extratropics to Tropical Andean Biodiversity.
Authors: Segovia Ricardo
Published: August 2024

The Andes are a relatively young mountain range with an impressive concentration of biodiversity. The biogeographic processes contributing to the hyperdiversity of the tropical Andes are still being unraveled. Novel mid- to high-elevation climates may have served as a biological corridor for the immigration of temperate-adapted lineages to lower latitudes, contributing unknown levels of diversity to this region. We tested the hypothesis that the genus Weinmannia corresponds to a lineage of extratropical origin that recently reached and then diversified extensively in tropical Andes. Using a 2bRAD seq approach to generate a time-calibrated phylogenetic tree for the genus, we found that the earliest diverging clades represent southern extratropical species, and a tendency for younger clades to be distributed towards northern latitudes. These results suggest a dispersal route for Weinmannia from the southern extratropics to the tropical Andes. As remnants of these lineages of southern origin converge with those that originated in other tropical and extratropical centers of diversification, we provide insights into the multisource origins of hyperdiversity in the modern montane forests of the tropical Andes.
Factors Associated with Duration and Exclusivity of Breastfeeding and Its Impact on The Prevention of Respiratory Diseases During Infancy
Authors: Orbea-Pichucho Carla , Dutan-Yupangui Luis , Chuquilla-Galárraga Andrea , Gálvez-Peralta Marcela , Andrés Tinoco-Serrano
Published: August 2024

Upper respiratory infections are the leading cause of infant morbidity and mortality in our environment. The National Health Organization recommends that all infants should be exclusively breastfed for the first six months of life. The aim of our work is to know the pattern of breastfeeding in our environment and its influence on the incidence of acute respiratory infections in infants in the first months of life. A representative sample of 2793 children under 6 months of age from the National Health and Nutrition Survey 2018 (ENSANUT) was used. A binary logistic linear regression model was used where Odds Ratio (OR) with their 95% confidence intervals (95% CI) were estimated for each of the independent variables. Our results show that those children who were exclusively breastfed showed a greater protective factor against acute respiratory infections compared to those children who were not exclusively breastfed. That is, our results show that exclusive breastfeeding during the first six months of life increased 2-fold (OR= 2.01; CI=1.91-2.17) the probability of not suffering from respiratory diseases. This result is statistically significant (p<0.05). It was also shown that those infants who received breast milk earlier from the time of birth have greater protection or developed greater immunity to upper respiratory tract infections (OR= 1.65; CI=1.41-1.94). Other significant protective factors are mother's age, mother's educational level and mother's area of residence. Breastfeeding is a protective factor against infections affecting the upper respiratory tract during the first 6 months of life. Therefore, our results coincide with several investigations that establish the potent immunomodulatory value of milk, which provides the infant with nutrients, precursors, probiotics, antimicrobial factors and anti-inflammatory agents, necessary for immune maturation and therefore reducing the incidence and severity of infectious diseases, and consequently infant morbidity and mortality.
The Basel Convention and Ship Decommissioning in the Economically Disadvantaged Nations: Bangladeshi Perspective
Authors:   Department of Law, North South University, Bangladesh. Email: ishtiaque.ahmed@northsouth.edu, Ahmed Ishtiaque
Published: August 2024

Bangladesh, the largest producer of steel from decommissioned ships, is the most dominant player in the global shipbreaking industry. However, managing hazardous waste generated from ship disposal remains a significant concern for the local and international communities. Bangladesh ratified both the relevant international treaties namely the Hong Kong Convention and the Basel Convention and incorporated their provisions in its domestic system. However, the country's waste management practices particularly at the downstream level are hindered by insufficient enforcement of the national waste policy, fragmented responsibilities for waste operators, generators, and transporters, and lack of technical guidelines and procedures. Using a comparative research methodology and a multimodal decision-making model namely the Analytical Hierarchy Process, this article attempts to single out laws and policies that need to be addressed by Bangladesh to fulfill its mandates under international laws, particularly the Basel Convention and effectively contribute to the sustainability in the global shipbreaking industry.
Integrated Management of the Mediterranean Fruit Fly (Ceratitis capitata) on Citrus in the Konispol, Albania
Authors:   Department of Plant Protection, Agricultural University of Tirana, Tirana, Albania.  Email: shahinishpend.212@gmail.com, Shahini Shpend , Skura Eugen ,   Department of Environment, Agricultural University of Tirana, Tirana, Albania.  Email: Eugen.Skura@outlook.com, Huqi Aris ,   Department of Plant Protection, Agricultural University of Tirana, Tirana, Albania.  Email: huqi_aris@outlook.com, Shahini Ermir ,   Department of Economics, Aleksander Moisiu University of Durres, Durres, Albania.  Email: ermir.sha.hini@hotmail.com, Ramadhi Adnan ,   Department of Plant Protection, Agricultural University of Tirana, Tirana, Albania.  Email: adnanram_16@hotmail.com, Sallaku Fatbardh ,   Department of Environment, Agricultural University of Tirana, Tirana, Albania.  Email: fa.sallaku_23@outlook.com
Published: August 2024

The Mediterranean fruit fly (Ceratitis capitata) is the main pest of citrus fruits, which can also infect other economically priority fruit plant species in an integrated global environment. Numerous populations of this insect contribute to the spread of fungi and microbes that cause secondary damage, such as fruit rot. Infestation of citrus orchards can lead to significant annual losses in crop size and quality. As a quarantine pest with high reproductive potential and spreading ability, the Mediterranean fruit fly is difficult to control and poses a serious threat to Albanian citrus exports due to concerns about infection or insecticide residues. The purpose of this study was to investigate the current state of integrated management of the Mediterranean fruit fly on citrus plants in the Konispol region, using innovative approaches. As part of this objective, the dynamics of the Mediterranean fruit fly population were studied using Trimedlure bait traps. The potential of organic integrated agricultural fruit production in the aspect of pest control was analysed. Integrated pest control programmes were described in detail, including a range of modern, safe population control methods and positioned as innovative, effective strategies for controlling the Mediterranean fruit fly. The study analysed the potential of modern tools and technologies for pest control. The areas of minimising the share of chemical protective equipment in the agricultural management system were outlined. As a result of the experiment, the effectiveness of the technique of mass trapping of pests was established. Comparative analysis of monitoring results at different farm plots was carried out. Based on the obtained data, the potential of management and technological measures to minimise the load on citrus plantations, combining the principles of environmental safety and economic feasibility, with the introduction of the latest systems for controlling and monitoring pest populations, was analysed.
Identifikasi Jenis Udang Hasil Tangkapan Nelayan di Kawasan Pesisir Kuala Langsa Provinsi Aceh
Authors: Tasya Jihan Nabila , Annisa Malika Nurul , Situmorang Praecety Bella , Muthmainnah Dwi
Published: August 2024

Kuala Langsa adalah sebuah Gampong yang terletak di Kecamatan Langsa Barat Kota Langsa, Provinsi Aceh, Indonesia. Potensi sumber daya alam  pesisir Desa Kuala Langsa sangat luas baik dari potensi  wisata, perikanan maupun sumber daya komersial. Terletak di kawasan padat penduduk, Kuala Kota Langsa tidak hanya terletak  di pinggiran kota, tetapi juga memiliki topografi yang unik sehingga menjadikannya ekosistem yang berpotensi memiliki karakteristik unik. Nelayan di Kuala Langsa tidak hanya menangkap ikan, tetapi juga berbagai jenis udang (kepiting) dan krustasea (cangkang keras), antara lain udang, rajungan, lobster, rajungan, remis dan kerabatnya. Sebagian besar spesies hidup di laut, namun banyak juga yang hidup di air tawar, dan ada pula yang hidup di darat pada tempat lembab. Tujuan penelitian ini adalah untuk mengidentifikasi jenis udang yang ditangkap  nelayan di Kuala Langsa, Aceh. Metode penelitian yang diterapkan  menggunakan metode purposive sampling dengan pengambilan sampel berupa wawancara langsung dan foto dari kamera telepon genggam. Dalam penelitian ini, 8 spesies dari 3 famili udang ditemukan di Kuala Langsa, provinsi Aceh. Di mana, jenis udang dari famili Penaeidae memiliki jumlah spesies dan spesimen terbanyak, sedangkan famili Gonodactylidae dan  Palaemonidae masing-masing hanya memiliki satu spesies.
Kajian Literatur: Penggunaan Teknologi Pembelajaran untuk Pengajaran Bioteknologi
Authors: Najira Najira , Riandi Riandi , Surtikanti Hertien Koosbandiah
Published: August 2024

Pada abad ke-21 ini, semua manusia akan menghadapi banyak tantangan global sehingga perlu mempersiapkan diri agar memiliki sejumlah keterampilan, pengajaran biologi tidak berubah secara substansial sejak tahun 1980an, meskipun ilmu pengetahuan telah berubah dengan pesat dimana isu pengajaran bioteknologi yang efektif masih harus diberikan. Tujuan review ini untuk mengetahui teknologi Pendidikan yang telah digunakan pada pembelajaran bioteknologi dengan metode penelitian berupa PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) yang merupakan pengkutipan pada artikel terindeks scopus yang terbit pada tahun 2017-2023 guna untuk mendata teknologi Pendidikan yang telah digunakan untuk pengajaran bioteknologi. Dalam Literature review ini terdapat 45% penggunaan secara digital, dan 11% menggunakan analog yang dimana menunjukan adanya kemajuan dalam pengajaran bioteknologi yang menggunakan media digital sebagai alat untuk mendukung proses belajar mengajar. Penggunaan teknologi pengajaran untuk belajar bioteknologi menunjukkan adanya kualitas yang sangat mempengaruhi hasil belajar siswa. Multimedia dalam website atau aplikasi pembelajaran interaktif yang menggunakan unsur gambar (visual) dan unsur suara pengiring (audio). Unsur-unsur di atas kemungkinan besar akan mempengaruhi penguasaan konsep siswa secara signifikan di kelas eksperimen dengan kehadiran animasi dalam media juga meningkatkan pemahaman konsep dan meningkatkan pembelajaran.
Inventarisasi Tanaman Pangan di Kawasan Pesisir Watu Ulo, Jember, Jawa Timur
Authors: Hariani Sulifah Aprilya , Pujiastuti Pujiastuti , Putri Frintiana Dyane
Published: August 2024

Penelitian ini bertujuan untuk menginvetarisasi tanaman pangan yang dimanfaatkan oleh masyarakat lokal di sekitar wilayah pesisir Watu Ulo, yang mencakup aspek jenis tanaman, cara pemanfaatan, dan metode pengolahan. Penelitian deskriptif eksploratif ini dilaksanakan pada Februari 2023 di sekitar wilayah pesisir Watu Ulo yang meliputi Dusun Watu Ulo dan Curah Rejo. Penelitian ini menggunakan teknik purposive snowball sampling dengan tahapan seleksi responden berdasarkan kriteria tertentu, wawancara semi-terstruktur, dokumentasi tanaman, dan inventarisasi tanaman. Data yang telah terkumpul selanjutnya dianalisis secara deskriptif untuk menentukan persentase, rata-rata, dan analisis use value. Temuan penelitian menunjukkan bahwa masyarakat setempat memanfaatkan 31 jenis tanaman dari 18 famili sebagai tanaman pangan. Pemanfaatan tanaman pangan mencakup fungsi sebagai makanan pokok (3%), makanan tambahan (14%), sayur-sayuran (9%), buah-buahan (9%), bahan minuman (30%), rempah-rempah (16%), dan bumbu masak (19%). Sebagian besar tanaman pangan berasal dari famili zingiberaceae. Bagian tanaman yang paling banyak dimanfaatkan adalah buah (35%). Hasil penelitian ini dapat digunakan sebagai sumber informasi tanaman pangan yang dimanfaatkan oleh masyarakat di kawasan pesisir Watu Ulo.
Implementasi Guided Inquiry dengan LKPD Saintifik untuk Meningkatkan Keterampilan Berpikir Kritis Peserta Didik
Authors: Zuhra Siti , Ulhaq Riza
Published: August 2024

Keterampilan berpikir kritis harus dibekali sedini mungkin agar peserta didik dapat menyelesaikan masalah secara cepat, tepat, dan logis hingga mampu menyelesaikan masalah secara holistik. Pembelajaran guided inquiry dengan LKPD saintifik merupakan kombinasi strategi pembelajaran dalam upaya meningkatkan keterampilan berpikir kritis. Penelitian ini dilaksanakan di MAN 1 Pidie pada materi struktur dan fungsi jaringan tumbuhan semester ganjil tahun ajaran 2021/2022. Penelitian dilaksanakan pada kelas eksperimen dengan pembelajaran guide inquiry dipadu LKPD saintifik dan kelas kontrol dengan pembelajaran konvensional. Sampel penelitian dipilih secara acak berjumlah 90 peserta didik. Instrumen penelitian menggunakan 10 soal uraian keterampilan berpikir kritis. Data keterampilan berpikir kritis dianalisis dengan menghitung rata-rata serta uji independent sample t-test. Hasil analisis uji beda rata-rata diperoleh thitung > ttabel (4.78>1.99), yang menunjukkan bahwa pembelajaran guided inquiry dengan LKPD saintifik dapat meningkatkan keterampilan berpikir kritis peserta didik. Peserta didik menjadi lebih kreatif dengan logika berpikir yang kritis, logis dan mendalam berdasarkan konsep sains, meliputi indikator: memberi penjelasan sederhana, membangun keterampilan dasar, menyimpulkan, dan memberi penjelasan lebih lanjut. Hanya pada indikator mengatur strategi dan taktik yang belum menunjukkan hasil yang baik, sehingga diperlukan latihan berkelanjutan.
Variasi Genetik Prion Protein Gene pada Kucing Domestik (Felis catus) Menggunakan Metode RFLP In Silico
Authors: Pinta Sari Rahma , Pratama Chelsylia Dara , Fatiha Fathma Dwi , Muharani Silvia , Achyar Afifatul
Published: August 2024

FSE adalah penyakit neurodegeneratif yang disebabkan oleh prion yang mempengaruhi semua keluarga kucing. Penelitian ini bertujuan untuk mengidentifikasi variasi genetik  dalam prion protein gene pada kucing domestik (Felis catus) menggunakan RFLP In silico. Penelitian ini merupakan penelitian deskriptif yang menyajikan karakteristik dari sampel yang diuji. Sampel yang digunakan yaitu sekuen prion protein gene dalam format fasta dari NCBI, dengan nomor identitas NCBI Popset 2445476754. Skrining enzim restriksi dilakukan menggunakan situs insilico.ehu.es. Metode RFLP in silico ini dilakukan menggunakan tools pada situs benchling.com dengan enzim restriksi yang diperoleh selama tahap skrining. Data yang telah didapatkan dianalisis secara deskriptif. Enzim restriksi yang digunakan yaitu enzim HhaI dengan sisi pemotongan pada basa G_CG'C dan enzim DpnI dengan sisi pemotongan pada GA'TC. Hasil restriksi dengan enzim HhaI pada 25 isolat prion protein gene Felis catus menghasilkan 4 variasi alel yaitu alel A1 (frekuensi alel 0,08), alel A2 (frekuensi alel 0,16), alel A3 (frekuensi alel 0,68) dan alel A4 (frekuensi alel 0,08). Restriksi yang dilakukan oleh enzim DpnI menghasilkan 2 alel yaitu alel B1(frekensi alel 0,84) dan alel B2 (frekuensi alel 0,16). Hasil penelitian ini dapat digunakan sebagai rujukan awal penelitian tentang gen Prion kucing domestik pada tahap yang lebih kompleks seperti bioinformatika, maupun pada tahap kerja laboratorium.
DETEKSI DAN IDENTIFIKASI KAPANG PADA PROSES BIODETERIORASI BATUAN CANDI PAWON
Authors: Nur Indahsari Putri , Octavia Bernadetta , Cahyandaru Nahar
Published: August 2024

This research attempts to know diversity of the moulds found in the biodeterioration process of Pawon Temple stone and identifying the type of damage caused by the moulds in the biodeterioration process of Pawon Temple stone. Survey sampling of Pawon Temple rocks based on the conditions: damp, weathered, cracked, and there is a yellowish-white crust. Sampling is done by swab technique using sterile cotton bud and scraping technique using scalpel. Identification of macroscopic and microscopic mold with profile matching method based on the book Pengenalan Kapang Tropik Umum, Descriptions of Medical Fungi, Identification of Pathogenic Fungi. The identification finds six genus are Penicillium (13%), Paecilomyces (59.4%), Mucor (15.9%), Stachybotrys (2.8%), Aspergillus (4.3%) and Cladosporium (2.8%). The genus of kalag in Pawon Temple is based on the search of libraries and journals potentially as agents of color formation, exfoliation of rocks and formation of postules and alevol.
REKONSTRUKSI MATERIAL PEMBANGUNAN BENTENG-BENTENG NUSANTARA
Authors: Swastikawati Ari , Agung Haldoko Leliek , Dwi Hanggoro Pramudianto , Gunawan Arif
Published: August 2024

Benteng Keraton Buton dan benteng Indrapatra termasuk benteng tradisional yang dapat mewakili beberapa benteng nusantara di Indonesia, dimana kontruksinya menggunakan pengetahuan dan teknologi tradisional berdasarkan tradisi masyarakat setempat kala itu. Terkait jenis material batuan dan komposisi bahan perekatpun menjadi menarik untuk dikaji agar dapat dibuktikan secara ilmiah. Tujuan kajian ini untuk mengetahui jenis batuan, komposisi mineral spesi/mortar, metode pembuatan spesi/mortar tradisional dan sifat fisik-mekanik spesi/mortar tiruan Benteng Indrapatra dan Keraton Buton. 
Metode penelitian dalam kajian ini adalah survai dan eksprimen didasarkan pada hasil analisis laboratorium komposisi mortar asli dan baru dari Benteng Keraton Buton dan Benteng Indrapata. 
Berdasarkan hasil survai dan analisis laboratorium diketahui bahwa Jenis batuan penyusun Benteng Keraton Buton berupa batu gamping non klastik, klastik dan kristalin, sedangkan Benteng Indrapatra berupa batu gamping klastik, batu gamping non klastik, batu andesit dan koral/terumbu. Perbandingan binder dan agregat mortar asli Benteng bervariasi, mulai dari 1:1, 1:2, 1:3, 1: 4 dan 2:3. Adapun Jenis mortar asli baik dari Benteng merupakan mortar kapur yang sangat didominasi oleh kehadiran kalsium karbonat (CaCO3) dengan persentasi kehadiran di atas 84%. Proses yang menentukan keberhasilan dalam proses pembuatan mortar kapur adalah proses pembakaran batu gamping dan proses perendaman kapur tohor.
Berdasarkan hasil tersebut sebaiknya mortar kapur diterapkan untuk perbaikan dalam rangka menjaga dan memelihara bahan cagar budaya, namun untuk kegiatan yang bersifat perkuatan struktur diperlukan bahan aditif untuk mempercepat proses pengeringan dan meningkatkan kekuatan mortar.
PENDOKUMENTASIAN NILAI RELIEF CANDI BOROBUDUR DALAM SENI TARI MELALUI FILM DOKUMENTER
Authors: Kasatriyanto Bambang , Sularsih Sri
Published: August 2024

Pendokumentasian Cagar Budaya terdapat berbagai metode yang dapat dilakukan antara lain sketsa, hand survey, fotografi, audio visual, fotogametri, 3D laser scanner, SIG (Sistem Informasi Geografis) dan GPS (Global Positioning System). Salah satu metode dokumentasi yang bisa dilihat dan didengar adalah pendokumentasian audio visual. Salah satu bentuk pendokumentasian audio visual yang mampu memberikan penjelasan lebih dalam dan mudah dipahami oleh masyarakat adalah film dokumenter.
Film dokumenter cagar budaya amatlah penting dalam upaya pelestarian Cagar Budaya. Informasi dan dokumentasi diperlukan sebagai sarana pengetahuan dan pemahaman tentang suatu arti dan nilai-nilai dari keberadaan suatu objek Cagar Budaya. Candi Borobudur merupakan salah satu Cagar Budaya yang memiliki nilai pesan moral yang tergambarkan dalam relief-relief candi. Jumlah keseluruhan relief terdapat 1.460 panil relief cerita yang tersusun dalam 11 deretan yang mengitari struktur candi, dan 1.212 panil relief dekoratif. Relief cerita di Candi Borobudur terbagi dalam beberapa bagian yaitu Relief Karmawibhangga, Relief Lalitavistara, Relief Jataka-Avadana, dan Relief Gandavyuha.
Rumusan masalah dalam artikel ini adalah bagaimana perancangan film dokumenter dalam hal ini Relief Candi Borobudur yang diaktualiasikan dalam seni tari dan nilai-nilai apa saja yang mampu disajikan dalam film documenter. Dari hasil penelaahan menunjukkan bahwa perancangan film dokumenter Menarikan Borobudur telah berhasil dilaksanakan menggunakan model cyclic strategy dengan menggunakan tahapan produksi film yaitu pra produksi, produksi, pasca produksi dan pengujian. Film dokumenter Menarikan Borobudur memenuhi kriteria sebagai salah satu metode Pendokumentasian Cagar Budaya dimana mendokumentasikan relief Jataka-Avadana Candi Borobudur dan mampu menunjukkan nilai-nilai yang terkandung di dalamnya yaitu nilai edukatif, inspiratif, rekreatif, dan regenerasi.
PERSPEKTIF ECO-SPIRITUAL DALAM PASAR JAWA KUNO
Authors: Widhianningrum Purweni , Eko Ganis Sukoharsono  , Roekhudin  , Yeney Widya Prihatiningtias
Published: August 2024

Penelitian ini bertujuan untuk mengeksplorasikan pentingnya nilai-nilai spiritual ketika bersentuhan dengan aspek ekologi, khususnya pada konteks pasar Jawa kuno. Penelitian ini merupakan jenis penelitian deskriptif-kualitatif dengan menggunakan penelaahan berbagai sumber tertulis (kepustakaan) sebagai bahan kajian analisa data. Hasil penelitian menunjukkan bahwa mekanisme pasar pada periode Jawa kuno selalu menekankan pentingnya proses keberlanjutan ekologis dengan aspek spiritual sebagai pendorongnya. Kebersamaan hidup dengan alam menjadikan masyarakat Jawa kuno memiliki pengetahuan luas tentang kesatuan relasi spiritual antara manusia (mikrokosmos) dengan alam (makrokosmos) atau dikenal dengan istilah eco-spiritual. Penghayatan terhadap kekuatan relasi eco-spiritual tersebut menjadi dasar masyarakat menjalankan aktivitas di pasar, sebagaimana terekam dalam relief karmavibhangga candi Borobudur. Relief karmavibhangga merepresentasikan ajaran Buddha tentang karma yang terkait dengan proses sebab akibat dari perbuatan manusia. Ajaran karma inilah yang kemudian menjadi nilai-nilai pendorong kesadaran eco-spiritual masyarakat Jawa kuno bersikap bijaksana mengelola beragam sumber daya alam secara wajar, tanpa menghancurkan ekosistem. Bagi mereka, alam memiliki unsur yang bernilai spiritual daripada sekedar realitas fisik yang bersifat material semata.
SIGNIFIKANSI JALUR SIRKULASI TERHADAP TRANSMISI NARASI CANDI BOROBUDUR
Authors: Kurniawan Jordi , Oktarina Freta
Published: August 2024

Candi Borobudur dicanangkan menjadi salah satu Destinasi Wisata Super Prioritas (DWSP) yang berbasis pendekatan storynomics tourism, yaitu pariwisata yang mengangkat narasi dan konten. Candi Borobudur mengandung narasinya tersendiri, akan tetapi perlahan narasi tersebut tidak tersampaikan kepada pengunjung akibat pengaturan sirkulasi yang tidak sesuai. Penelitian ini merupakan penelitian arsitektur dilakukan untuk mengidentifikasi dan menganalisis jalur sirkulasi yang ada di Candi Borobudur kemudian memahami signifikansi jalur sirkulasi terhadap transmisi narasi Candi Borobudur. Penelitian menggunakan metode analisis deskriptif secara arsitektural pada jalur sirkulasi dan metode sejarah melalui studi pustaka. Sumber data berasal dari hasil observasi lapangan dan pustaka sejarah atau historiografi. Dari hasil identifikasi dan analisis yang dilakukan pada jalur sirkulasi, kemudian dikaitkan dengan perannya dalam mentransmisikan narasi Candi Borobudur. Temuan penelitian yang diperoleh berupa Candi Borobudur menyimpan narasi dalam bentuk perjalanan transformasi ruang arsitektural yang mewakili tataran atau tahapan menuju pencerahan dan panel-panel relief naratif yang tersedia mengajarkan tentang sifat-sifat kesempurnaan. Pengaturan jalur sirkulasi pengunjung yang sesuai konteks Borobudur berperan signifikan dalam keberhasilan transmisi narasi Candi Borobudur.
KONSERVASI ARTEFAK MATA UANG CINA BERBAHAN PERUNGGU DARI DESA KEPATIHAN, TULANGAN, SIDOARJO DENGAN MENGGUNAKAN BAHAN KONSERVAN JERUK NIPIS DAN ALKALI GLISEROL
Authors: Malino Gabriela Virginia , Erwin Mansyur Ugu Saraka  , Khadijah Thahir Muda  , Ira Fatmawati
Published: August 2024

Penelitian ini berfokus untuk mengetahui efektivitas penggunaan bahan konservan pada artefak koin berbahan perunggu yang merupakan hasil kegiatan peninjauan di Desa Kepatihan, Tulangan, Sidoarjo yang dilakukan oleh Balai Pelestarian Kebudayaan Wilayah XI Jawa Timur Tahun 2008 dan saat ini tersimpan di Laboratorium Balai Pelestarian Kebudayaan Wilayah XI. Dalam penelitian ini, bahan konservan yang digunakan adalah jeruk nipis dan alkali gliserol. Metode yang digunakan terbagi menjadi dua, yaitu penggosokan dan perendaman. Pembersihan menggunakan jeruk nipis untuk menghilangkan korosi dilakukan melalui penggosokan dan perendaman, sedangkan pembersihan menggunakan alkali gliserol dilakukan melalui perendaman yang dilakukan dua kali selama 5 menit. Hasil penelitian menunjukkan bahwa penggunaan jeruk nipis lebih efektif daripada penggunaan alkali gliserol dengan metode penggosokan. Hal ini disebabkan oleh kontak langsung antara metode penggosokan dengan artefak serta kandungan asam yang terkandung dalam jeruk nipis.
TURKISH EXAMPLE OF PRIORITIZATION AND RESTRICTION DECISIONS IN MEDICINE ACCESS: EVALUATION BASED ON TWO INNOVATIVE DRUGS
Authors: Vural Elif Hilal , Kılıc Ensar Korkut , Atikeler Enver Kağan , Gümüşel Bülent
Published: August 2024

Objective: Drug licensing, price, and reimbursement are essential for medical access. This study examines US, EU, and Turkish reimbursement for innovative medicines and evaluates Türkiye's recent licensing and reimbursement decisions.
Material and Method: Nivolumab, an anticancer medicine, and Evolocumab, a hyperlipidemia treatment, were studied. Web-based searches of FDA, EMA, and TİTCK offical websites revealed authorized indications and approval dates for chosen medications.
Result and Discussion: Nivolumab has been authorized for 11 indications by the FDA and 10 by the EMA, although it is only approved for 8 in Türkiye. Evolocumab has been authorized for three indications by the FDA, three by the EMA, and two in Türkiye. Nivolumab was approved in Türkiye an average of 24.0 months after the FDA and 20.4 months after the EMA. In Türkiye, the indications for this medicine were reimbursed 27.6 and 25.2 months later, respectively. The FDA and EMA authorized the indications for evolocumab in Türkiye 10 months and 13.2 months later, respectively. The FDA and EMA authorized evolocumab's single reimbursement indication in Türkiye after 72.0 and 74.4 months, respectively. Our investigation found that some patient groups were given priority by limiting pharmaceuticals with high budget expectations, and these prioritizing decisions were made to secure patients' access to therapy.
PENYELESAIAN SENGKETA DAN AKIBAT HUKUM HAK GUNA USAHA UNTUK PERKEBUNAN
Authors: Yunantha Rachmat , Gultom Elfrida Ratnawati
Published: August 2024

Hak Guna Usaha is the right to cultivate land directly controlled by the State, within a certain period of time, for agricultural, fishery or livestock enterprises. Business Use Rights can be owned by Indonesian citizens and legal entities that have been established in Indonesia according to Indonesian law and are domiciled in Indonesia. This research is normative juridical research. The type of approach in the writing method, the author uses a statutory approach, comparative approach, historical approach and conceptual approach. The data obtained in this study were analysed using a qualitative method, namely a data analysis method that classifies and selects the data obtained. The results of the analysis are presented descriptively so that a descriptive-qualitative description of the research results is obtained and described in the form of sentences which are then organized and systematic. For example, the case of the Constitutional Court Decision Number 859/Pid.Sus/2017/PN.Kpn. that the defendant Ari Ismanto Bin Tukirin in January 2016 to October 2017 took place on PTPN XII Kebun Pancursari Afdeling Sumberkerto/Sumbermanggis (SK/SM) Sumbermanggis Hamlet, Tegalrejo Village, Sumbermanjing Wetan District, Malang Regency. Dispute settlement between PT Perkebunan Nusantara XII and Tegalrejo Village community by conducting 2 (two) efforts, namely through litigation and non-litigation. The legal consequences after the dispute between PT Perkebunan Nusantara XII and Tegalrejo Village community is that the panel of judges with several considerations determined that the actions committed by one of Tegalrejo Village residents as the defendant was declared to have violated the law.Keywords: Cultivation Rights, Plantation, Dispute Resolution.
URGENSI TENTANG PERATURAN SURROGACY (SEWA RAHIM) DI INDONESIA
Authors: Arifin Husnul , Gultom Elfrida Ratnawati
Published: August 2024

A wife who has experienced uterine cancer which resulted in her uterus being removed so that it is no longer possible to have genetic children from the ovum and sperm of a legitimate married couple, while children are one of the gifts that give happiness to married couples, through the In Vitro Fertilization (IVF) Program generally used by married couples who find it difficult to have children, namely the wife has difficulty getting pregnant so she cannot raise the fetus in her own womb, surrogacy has not yet been legalized by regulation, this research uses a legal approach and supporting books which is what this paper aims to do. provides a solution for married couples who do not have a uterus to have children through surrogacy.
ANALISIS FAKTOR SOSIAL EKONOMI YANG MEMPENGARUHI KEPUTUSAN IBU TIDAK MEMBERIKAN ASI EKSKLUSIF
Authors: Utami Utami , Yulita Hendra , Noorma Nilam , Rofiqoh Rofiqoh , Anwar Seniwaty
Published: August 2024

Based on an initial survey, the number of mothers who do not provide exclusive breastfeeding increases every year, so there are various factors that influence the lack of optimality in exclusive breastfeeding. The purpose of the study was to determine the relationship between socioeconomic factors that influence mothers' decisions not to provide exclusive breastfeeding. This type of research uses quantitative with a cross sectional approach. The research was conducted in June 2022 using consecutive sampling. The sample amounted to 109 people. The results showed that there was a relationship between education level (p value: 0.006), working status (p value: 0.001) on exclusive breastfeeding. It is recommended for health workers, especially those who provide treatment to mothers and children, it is hoped that the results of this study can be used as discussion or reference material related to improving the performance of health services in a place or area of coverage of their work area. Keywords: Exclusive breastfeeding, work, education
HUBUNGAN ANTARA BEBAN KERJA DAN STRES KERJA DENGAN KUALITAS TIDUR PERAWAT INSTALASI GAWAT DARURAT
Authors: Situmeang Lamria , Kadir Abd , Saputra M. Khalid Fredy , Yulis Rahma , Werdini Yoessy Etna
Published: August 2024

Poor sleep quality is a condition where, when someone is sleeping, they feel the desire to wake up from sleep as soon as possible. Workload and work stress have an important effect on sleep quality in nurses. The purpose of the study was to determine the relationship between workload and work stress with the quality of sleep of emergency department nurses. The type of research is quantitative with a cross sectional design. The research was conducted at PKU Muhammadiyah Gombong Hospital in July 2022. The research sample was nurses in the Emergency Department of PKU Muhammadiyah Gombong Hospital, totaling 41 with the sampling technique using total sampling. The research instrument used a research questionnaire. Data analysis was done univariate and bivariate. The results showed there was a relationship between workload (p value: 0.002) and work stress (p value: 0.000) with sleep quality in nurses.  It is recommended for nurses to make the best use of rest time before work, such as doing sleep hygiene by limiting food and drinks before bed, starting to sleep and waking up at the same time, limiting napping hours, creating special rituals before bed, creating a comfortable sleeping environment, and exercising regularly in the morning or afternoon.
ANALISIS FAKTOR SOSIAL EKONOMI DAN LINGKUNGAN TERHADAP KEJADIAN TUBERKULOSIS
Authors: Santoso Raden Bagus Edy , Djafar Tanwir , Sulistiyani Sulistiyani , Pangaribuan Resmi , Lellu Amos
Published: August 2024

Tuberculosis (TB) according to the World Heallth Orgalnizaltion (WHO) as the second deadly disease in the world in 2021 after Covid-19, and became the 13th (thirteen) as the main cause of death worldwide. Indonesia is ranked third in the world with the highest burden of TB cases after India and China. The trend of tuberculosis case finding rates for all types per 100,000 population in Lampung Province during 2016-2020 tends to increase. The purpose of the study was to determine the relationship of socioeconomic and environmental factors to the incidence of tuberculosis. The type of research was quantitative with a case control approach. The research was conducted in September-October 2023 at UPTD Puskesmas Tanjung Agung. The sample amounted to 58 respondents (29 case groups and 29 control groups). The sampling technique used purposive sampling. The research instrument consisted of a questionnaire sheet. The results showed that there was a relationship between economic status (p value: 0.009) and home hygiene (p value: 0.001). It is recommended that the Health Office carry out early detection of pulmonary tuberculosis problems routinely, in addition to carrying out preventive, promotive efforts in preventing pulmonary tuberculosis. The government, in this case the UPTD Puskesmas Tanjung Agung, conducts counseling about pulmonary tuberculosis and the dangers of smoking. The government also tries to implement programs to improve the economic status of the community as a priority or program.
Human umbilical cord-derived mesenchymal stromal cells for the treatment of steroid refractory grades III-IV acute graft-versus-host disease with long-term follow-up
Authors: Niu Jing-wen , Li Yuhang , Xu Chen , Sheng Hongxia , Tian Chong , Ning Hongmei , Hu Jiangwei , Chen Jianlin , Li Botao , Wang Jun , Lou Xiao , Liu Na , Su Yongfeng , Sun Yao , Qiao Zhuoqing , Wang Lei , Zhang Yu , Lan Sanchun , Xie Jing , Ren Jing , Peng Bo , Wang Shenyu , Shi Yanping , Zhao Long , Zhang Yijian , Chen Hu , Zhang Bin , Hu Liangding
Published: August 2024

Introduction

Mesenchymal stromal cells (MSCs) have been extensively studied as a potential treatment for steroid refractory acute graft-versus-host disease (aGVHD). However, the majority of clinical trials have focused on bone marrow-derived MSCs.

Methods

In this study, we report the outcomes of 86 patients with grade III-IV (82.6% grade IV) steroid refractory aGVHD who were treated with human umbilical cord-derived mesenchymal stromal cells (UC-MSCs). The patient cohort included 17 children and 69 adults. All patients received intravenous infusions of UC-MSCs at a dose of 1 × 106 cells per kg body weight, with a median of 4 infusions (ranging from 1 to 16).

Results

The median time between the onset of aGVHD and the first infusion of UC-MSCs was 7 days (ranging from 3 to 88 days). At day 28, the overall response (OR) rate was 52.3%. Specifically, 24 patients (27.9%) achieved complete remission, while 21 (24.4%) exhibited partial remission. The estimated survival probability at 100 days was 43.7%. Following a median follow-up of 108 months (ranging from 61 to 159 months), the survival rate was approximately 11.6% (10/86). Patients who developed acute lower GI tract and liver GVHD exhibited poorer OR rates at day 28 compared to those with only acute lower GI tract GVHD (22.2% vs. 58.8%; p= 0.049). No patient experienced serious adverse events.

Discussion

These finding suggest that UC-MSCs are safe and effective in both children and adults with steroid refractory aGVHD. UC-MSCs could be considered as a feasible treatment option for this challenging conditon. (NCT01754454).
Transforming Philippines Events: Strategic Planning, Marketing, and Sustainability for Dynamic MICE and Beyond (2019-2023)
Authors: Galapate Wendell L , Inducil Joemar , Animas Melbert
Published: August 2024

In an ever-evolving landscape of worldwide company as well as tourism, the Conferences, Motivations, Conferences, as well as Exhibitions (MICE) sector has become an essential chauffeur of financial growth, expertise exchange, and also cultural enrichment. This term paper explores the transformative trip taken on by the Philippines' events market from 2019 to 2023, concentrating on the tactical planning, marketing strategies, as well as sustainability efforts that have formed its trajectory. The Philippines, renowned for its natural elegance as well as warm friendliness, provides a fascinating background for MICE activities, which have actually progressively come to be critical in harnessing the country's potential on the international phase. This study utilizes a thorough strategy, combining qualitative as well as measurable study methods. Our objective is to not only give an alternative summary however also to uncover nuances that inform the methods reviewed. By outlining our research procedures, from data collection to analysis, we enhance the paper's trustworthiness and also transparency.
Taking into account the above, this research paper finishes in a clear thesis statement that envelops its core focus and purpose: to shed light on the transformative journey of the Philippines' occasions market, highlighting its calculated evolution, marketing characteristics, and sustainability efforts within the world of MICE activities. Subsequently, the paper concludes this introduction with a rundown that sneak peeks the future areas, serving as a roadmap for viewers as they navigate through the details of the Philippines' trip in redefining its events landscape.
Strategy to Increase the Digitalization Capacity of Homestay Managers in Pandanrejo Tourism Village, Indonesia
Authors: Gusti Agung I Gusti Agung Wahyu Adrian , Edwin Adriansyah  , Brantas  , Jatmiko Edy Waluyo
Published: August 2024

This research aims to describe community problems in Pandanrejo Tourism Village in managing homestays and implementing community empowerment that can be carried out in development in the village. The data sources for this research are primary data and secondary data. Primary data from this research consists of interviews and observations, while secondary data comes from literature and electronic media studies. This research uses several data collection tools, including interview guides, checklists, and sound, image, or video recording equipment. Data analysis in this research uses an interactive model by Miles and Huberman along with data paraphrasing techniques by carrying out interactive qualitative data analysis activities that continue continuously until completion, until the data is saturated. The activities of this analysis model consist of data reduction, data presentation, drawing conclusions, and verification. The results of the analysis that has been carried out show that the digital literacy level of homestay managers is 75%, they have basic knowledge about the use of hardware and software, 90% of homestay managers have internet access with adequate speed, and 40% face limited financial resources to invest in equipment. Analysing this provides a clear picture of the challenges and the steps that can be taken to overcome these problems. Based on the data that has been analysed, it can be concluded that efforts to increase digital literacy, website development, online marketing strategies, and internet accessibility are important keys to strengthening the digitalization of homestay managers.
Pandanrejo Tourism Village Digital Branding Identity Analysis
Authors: Dendy Sundayana  , Linandar Tanuwijaya  , Mohamad Ridwan  , Darmawan Sundayana  , Odang Rusmana
Published: August 2024

Tourism is one of the factors affected by the COVID-19 pandemic, but after the COVID-19 pandemic, tourism began to rise. There was the phenomenon of "Revenge Tourism," or revenge tourism, which increased interest in travelling after the COVID-19 pandemic. There is also an alternative trend in the form of tourist villages, which are increasingly growing. Pandanrejo Tourism Village is one of the tourist villages in Indonesia and has various attractions and tourism products that are attractive to tourists. The aim of this research is to determine how the digital branding of a tourist village can be right on target according to the target market they determine and what the condition of the village's digital branding identity is. This must be supported by the use of strong branding, both digital and conventional. However, for branding the Pandanrejo Tourism Village, there are still several things that can be maximised so that digital communication through digital branding includes concepts and visual designs carried out in tourism products so that it can maximise the target market and positioning of the Pandanrejo Tourism Village. This research approach uses a qualitative research approach with several key sources to be used as primary data for analysis and involves many stakeholders, such as tourist village managers, community leaders, village officials, and visitors who came to this village. The findings in this research are the condition of the digital branding of the Pandanrejo tourist village and the implications for the information conveyed to visitors.
Kazak Türkçesinde Renklerin Bitki Adlandırmalarında Kullanımı
Authors: Akduruş Turgay
Published: August 2024

Bitki adları, tıpkı diğer kavram adları gibi zorunluluktan doğmuştur. Tüm toplumlarda insanlar bitkileri adlandırırken onları diğer bitkilerle karıştırmamak, diğerlerinden ayırt edebilmek için onların her birine özel bir isim vermiştir. Kazakistan’da floranın çeşitliliği bitki adlandırmalarındaki zenginliği sağlarken bu bitkilerin isimlendirilmesinde renk adları kavram alan adlarının başında yer alır. Renk adları yönünden zengin ve işlevsel bir dil olan Kazak Türkçesinde bitki adlarının önemli bir kısmı aḳ jelimsabaḳ “bir karanfil türü”, börte juwsan “tüylü ve yerde uzanan bir bitki türü”, ḳızıl baldırlar “bir tür su yosunu” vb. bu anlayış doğrultusunda oluşmuştur. Renklerin bitki adları ile kullanımı esnasında Kazak dünya görüşünün renklere yüklediği anlam açıkça belirir. Kazak dilindeki bitki adlarının ak, kara, kızıl, sarı ve ala gibi renklerle daha yoğun; küreñ, ‘kızıl kahverengi’, şubar ‘alacalı renk’, şegir ‘sarımtırak’ gibi renklerle ise daha az kullanıldığı görülür. Renklerin bitkileri adlandırma esnasında onların tasvir edici özelliğinden yararlanılır. Kazak Türkçesinde renklerin çok sayıda bitki adlandırmasında görev aldığını gösteren bu çalışma renk adları araştırmalarına katkı sağlamak için hazırlanmıştır. Çalışmaya kaynaklık eden dil malzemeleri Kazak dilinin en kapsamlı söz varlığı durumundaki 16 ciltlik Kazak Ädebi Tilinin Sözdigi adlı eserin taranması yoluyla elde edilmiş ve veriler sonrasında eş zamanlı dil bilim yöntemiyle incelenmiştir.
Anahtar Kelimeler: Renk Adları, Bitki Adları, Kazak Türkçesinde Renk Adları, Kazak Türkçesinde Bitki Adları, Renkler ve Bitkiler.
Batı Grubu Ağızlarının Bir Bölümünde Kullanılan {-DXnAk} Zarf-Fiil Eki ve İşlevleri
Authors: Gökçe Hüseyin
Published: August 2024

Zarf-fiiller, asıl fiilde meydana gelen eylemin zamanını, sebebini, durumunu ve tarzını bildiren dilbilgisel yapılardır. Türkçe, zarf-fiil ekleri yönünden zengin bir dildir ve bu durum, Türkçenin ifade zenginliğini gösterir. Türkçede zarf-fiil ekleri ile birçok yargı, tek bir cümle ile ifade edilebilir. Zarf-fiil ekleri, basit ve birleşik yapılı olmak üzere iki şekilde incelenir. Basit yapılı zarf-fiiller, Türkçenin ilk devirlerinden itibaren kullanılırken birleşik yapılı zarf-fiiller, tarihsel süreç içerisinde zamanla meydana gelir. Bu şekilde oluşan birleşik zarf-fiil yapıları, Türkiye Türkçesinde de kullanılır. Birleşik zarf-fiiller, Türkiye Türkçesine kıyasla Türkiye Türkçesi ağızlarında çok daha fazladır. Ağızlar, Türkiye Türkçesinde kullanılmayan birçok birleşik zarf-fiili bünyesinde barındırır. Söz konusu birleşik zarf-fiillerden biri de Balıkesir, Çanakkale, Manisa, Bursa, Kütahya ve Uşak ağızlarında tespit edilen {-DXnAk} zarf-fiil ekidir. Bu çalışma, {-DXnAk} zarf-fiil ekinin bu ağızlardaki kullanımına odaklanmıştır. Çalışmada öncelikle {-DXnAk} zarf-fiil ekinin yapısı hakkında bazı açıklamalar yapılmış, ardından bu ekin söz konusu ağızlarda hangi işlevlerle kullanıldığına değinilmiştir. Yapılan inceleme sonucunda {-DXnAk} zarf-fiil ekinin ilgili ağızlarda zamandaşlık, zamanda sonralık, zamanda öncelik, şart ve sebep bildirme işlevleri ile kullanıldığı görülmüştür.