bluuebunny/crossref_metadata_2025 huggingface dataset:
Revisão Bibliográfica sobre a produção de modelos multissensoriais de Astronomia para o ensino inclusivo de pessoas com deficiência visual
Authors: De Araujo Freire Vagner Diego , Carvalho Tassiana
Published: November 2024

Este trabalho procura compreender como a literatura na área de ensino de astronomia tem abordado a questão da inclusão. O objetivo foi realizar uma revisão bibliográfica de trabalhos que produziram ou utilizaram materiais didáticos multissensoriais voltados à inclusão de discentes com deficiência visual, publicados entre 2002 e 2024. Como perspectiva teórica, adotam-se as perspectivas de Vigotski e Camargo, com relação a compreensão sobre a pessoa com deficiências e os processos de ensino e de aprendizagem. Selecionou-se 35 trabalhos, os quais foram sintetizados e categorizados. Constatou-se uma predominância de modelos da Terra, do Sol e da Lua, bem como os tópicos de astronomia que mais apareceram foram: modelos celestes, Sistema Solar e o sistema Sol-Terra-Lua. Possivelmente, a escolha dos temas foi influenciada pelos documentos curriculares. Embora o número de publicações tenha crescido, notou-se que faltavam modelos sobre outros objetos do Sistema Solar, e para a abordagem de conceitos mais complexos, como estrelas e universo. Noções de tridimensionalidade e proporcionalidade nem sempre foram consideradas, o que pode levar ao desenvolvimento de concepções equivocadas. Os resultados também indicam que além de ampliar temáticas, é importante desenvolver mais aplicações desses modelos, bem como realizar pesquisas sobre seu potencial para a aprendizagem de conceitos.
Palavras-Chave: Ensino de Astronomia Inclusivo, Deficiência Visual, Materiais Didáticos Multissensoriais, Revisão Bibliográfica.
To the Density and Distribution of Heterochromatin in Differentiating, Maturing and Apoptotic Cells Represented by Granulocytic, Lymphocytic and Erythrocytic Precursors
Authors: Smetana Karel , Klamová H. , Jirásková I. , Hrkal Z.
Published: November 2024

The present study was undertaken to provide more information on the density and distribution of heterochromatin in early and advanced stages of the granulocytic, lymphocytic and erythroid development. Heterochromatin was visualized using a simple cytochemical method for the demonstration of DNA followed by computer-assisted densitometry of the digitized images. The largest heterochromatin density in early proliferating stages of all studied blood cell lineages was noted in the perinucleolar region and centrally located chromocentres. In contrast, the heterochromatin density at the nuclear membrane was significantly lower. In advanced nonproliferating stages or apoptotic cells the heterochromatin density increased and was similar in all nuclear regions, i.e. in the perinucleolar regions, chromocentres, and at the nuclear membrane. Thus, such observations indicated that the heterochromatin condensation in the perinucleolar region and chromocentres, i.e. in “gene-rich nuclear regions”, of differentiating and maturing progenitors of blood cells preceded that at the nuclear periphery.
Femoral Bone Microstructure in 1-Month-Old Non-transgenic versus Transgenic Rabbits with the WAP-hFVIII Gene Construct
Authors: Martiniaková Monika , Omelka R. , Grosskopf B. , Smoláriková V. , Bauerová M. , Chrenek P.
Published: November 2024

Differences in microscopic structure of the femur between 1-month-old transgenic rabbits carrying the hFVIII gene and non-transgenic rabbits were investigated. Bone microstructure was evaluated from the point of view of qualitative and quantitative histological characteristics. We identified fibrolamellar bone tissue only in the transgenic animals. Measured values for area, perimeter of the Haversian canals and minimum diameter of the primary osteons’ vascular canals were higher in 1-month-old transgenic individuals (P < 0.05; P < 0.001). We also observed lower concentrations of Ca, P, K, solids, and total mineral content in femora of transgenic rabbits. A statistically significant difference was observed for the concentration of Ca (P < 0.05). Our results indicate evident changes in both qualitative and quantitative histological characteristics of the femur, which result especially in better blood supply and slightly reduced mineralization process in 1-month-old transgenic rabbits.
Differences in Expression of Cholesterol 7α-Hydroxylase between PHHC and Wistar Rats
Authors: Hubáček Jaroslav A. , Bobková D. , Bohuslavová R. , Poledne R.
Published: November 2024

PHHC rats represent a suitable experimental model of polygenic hypercholesterolemia. It has been found that its metabolic defect is not related to alimentary cholesterol absorption and LDL clearance. We have tested possible changes in cholesterol clearance from the liver to bile acids by analysis of the expression of the cholesterol 7α-hydroxylase (cyp7A1) gene in PHHC (N = 20) and Wistar (controls) (N = 19) male rats. The animals were fed standard laboratory diet (CD) or control diet containing 5% fat and 2% cholesterol (HCD) for two weeks. SSCP and RT-PCR were used for mutation analysis and study of gene expression, respectively. Although the basal cholesterolemia in PHHC was similar to controls (1.80 ± 0.48 and 1.52 ± 0.39 mmol/l, respectively), it rose in rats fed on HCD to 9.81 ± 1.65 mmol/l in PHHC rats and only to 2.19 ± 0.41 mmol/l in controls. Similarly to the basal cholesterol concentration, the gene expression of cyp7A1 in the liver of rats on CD was the same in both compared groups on the control diet. In controls on HCD, cyp7A1 gene expression increased almost 4-fold immediately on the first day and achieved up to ~ 20-multiple basal expression in the end of the feeding period. Compared to the controls, after switching to HCD the cyp7A1 gene expression in PHHC rats did not change dramatically. These results suggest that the cyp7A1 gene plays an important role in development of hypercholesterolemia in PHHC rats.
O NARRADOR NA TRANSPOSIÇÃO INTERMIDIÁTICA DE MEMÓRIAS PÓSTUMAS
Authors: Gomes Marques Márcia , Alves Gedy Brum Weis
Published: November 2024

Este artigo aborda o aproveitamento de obras anteriores como um traço característico da produção cultural contemporânea, com o estudo de caso da adaptação de Memórias Póstumas de Brás Cubas (1881), de Machado de Assis, para o filme Memórias Póstumas (2001), de André Klotzel. Verifica-se que o texto derivado atualiza elementos estilísticos do texto-fonte, explicitando seu projeto comunicativo a partir da seleção dos aspectos que retoma em seu arranjo composicional. Observa-se como a focalização, o ponto de vista e a autoconsciência do narrador, aspectos de prestígio da obra machadiana, são repropostos no filme a partir da corporificação do narrador delegado, o “defunto autor”, que conta e mostra suas memórias.
A ATRIBULADA ADAPTAÇÃO DO LIVRO DUNE PARA FILME, POR DAVID LYNCH
Authors: S. Branco Luís Carlos S.
Published: November 2024

Dune é uma obra de Ficção Científica portentosa. Para além da densidade material (tem cerca de seiscentas páginas), é uma obra literária de grande escopo, onde perpassam várias problemáticas, ainda hoje, contemporâneas. Além disso, o autor concebeu toda uma geografia e cosmologia de raiz. Parece muito cinematográfica, e é-o, mas isso não quer dizer que seja de fácil adaptação cinematográfica. Pelo contrário, é uma obra quase impossível de transpor para a linguagem cinemática. Vários autores tentaram e falharam clamorosamente. A mais célebre dessas tentativas foi a encetada por David Lynch, em 1984, e é sobre ela que, aqui, me debruçarei. Começarei por descrever algumas caraterísticas do livro e traçarei, muito brevemente, a cronologia das várias tentativas goradas de adaptação para filme. Darei, depois, conta de todo o processo vivido por Lynch e pela sua equipa, desde a escrita do guião até às filmagens e posterior receção de público e da crítica. Analisarei, com especial cuidado, as diferenças e similitudes entre a obra literária e o filme, e tentarei explicar as razões que levaram a que esta adaptação falhasse, analisando criticamente todas essas vicissitudes.
MAIS HUMANO QUE O HUMANO: DE PHILIP K. DICK A SPIKE JONZE — CONSTRUÇÃO DE PERSONAGENS E FOCALIZAÇÃO
Authors: Miranda Allana Dilene de Araújo de , Mousinho Luiz Antonio , Falcão Thiago Pereira
Published: November 2024

Este artigo se dedica à análise das personagens nos textos Do androids dream of electric sheep?, de Philip K. Dick, Blade Runner (Ridley Scott, 1992) e Her (Spike Jonze, 2013). Atentando inicialmente às estratégias de construção de personagens utilizadas, o trabalho aponta as várias semelhanças entre seus objetos, bem como as expressivas divergências. Inicialmente, o artigo tece considerações sobre as personagens ficcionais, com base nos ensaios de Antonio Candido e Anatol Rosenfeld (2005). Em seguida, aborda a focalização como ferramenta de construção de personagens nas três obras. Ao fim do trabalho, é possível perceber mudanças na representação das inteligências artificiais — vistas primeiramente como antagonistas que buscam atingir um patamar igualitário ao dos seres humanos, deixam de almejar materialidade física para chegar a outra forma de existência.
“O MODELO COPIA O REAL, SEM DETURPAR”: A MAQUETE NA ADAPTAÇÃO CINEMATOGRÁFICA CARLOS DE OLIVEIRA – SOBRE O LADO ESQUERDO (2007), DE MARGARIDA GIL
Authors: Pereira Patrícia Resende
Published: November 2024

O propósito do artigo é investigar a maneira como a maquete, um dos objetos criados pela família de Finisterra: paisagem e povoamento (1978), livro do autor português Carlos de Oliveira, ganha outra significação na adaptação para os cinemas das obras do poeta homenageado em Carlos de Oliveira – Sobre o lado esquerdo, de 2007. Dirigido por Margarida Gil, a partir do roteiro escrito por ela, em parceira com Manuel Gusmão, ensaísta e também poeta, nota-se que a maquete, produzida pelo adulto na narrativa, na transposição para as telas é mencionada em cenas concentradas na reflexão da escrita por parte de Carlos de Oliveira, bem como de aspectos biográficos. Há, então, certo deslocamento quanto ao emprego do objeto no livro e no cinema, condição a ser investigada no artigo.
DO COLONIAL AO CORPORAL: CONFIGURAÇÕES DO GÊNERO HORROR EM O ENIGMA DO OUTRO MUNDO
Authors: Meireles da Silva Alexander
Published: November 2024

Este artigo propõe a análise da noveleta “Who Goes There?” [“O enigma do outro mundo”] (1938), de John W. Campbell Jr. e a adaptação cinematográfica The Thing [O enigma do outro mundo] (1982), dirigido por John Carpenter e com roteiro de Bill Lancaster, através das lentes do horror colonial e do horror corporal. Como será demonstrado, o texto de 1938 e sua versão para o Cinema de 1982 têm como pontos em comum o fato de se alinharem às ansiedades dos anos de 1930 e 1980 ligados ao corpo e as possíveis ameaças contra a sua integridade. Em nossa leitura, o horror é uma forma cultural fóbica, no sentido de que ele visa produzir uma reação específica – medo e repugnância – baseada nos medos e ansiedades de momentos históricos específicos, que assumem disfarces metafóricos diversos. De fato, o estudo das duas obras evidencia que a noveleta de Campbell, no qual o temor da contaminação se mostra dominante, está alinhada com o discurso vigente na América do período entre guerras, marcado por atitudes e políticas xenofóbicas e racistas. Da mesma forma, o filme dos anos 80 captura os debates elencados pela contra-cultura e movimentos civis relacionados à discussão de construções sociais normativas do corpo.
MERLIN E MORGANA: MAGIA BRANCA E MAGIA NEGRA NA TELINHA E NA TELONA
Authors: Breton Justine
Published: November 2024

A lenda do Rei Artur, amplamente construída sobre uma lógica dual e maniqueísta, opõe duas figuras de bruxos que contribuem para a renovação constante da narração: Merlin, o mago conselheiro dos soberanos, e a fada Morgana, bruxa maléfica e ávida por poder. Embora ancorada na tradição literária medieval, essa repartição de gênero das personagens entre o Bem e o Mal constitui uma criação do século XX, largamente desenvolvida pelo cinema e pela televisão. Este artigo propõe um olhar diacrônico sobre a construção deste casal antitético, estudando a evolução dessas duas figuras essenciais da lenda arturiana e suas relações, desde sua aparição no século XII, em obras francesas e inglesas, até as maiores produções cinematográficas e televisivas da cultura popular: Os cavaleiros da távola redonda (1953), A Espada era Lei (1963), Excalibur (1981), mas também as séries televisivas Kaamelott, Merlin e Camelot.
O insólito ficcional da tela aos livros, dos livros à tela: adaptações, recriações, traduções, menções
Authors: Anselmi Matangrano Bruno , Zó Ramiro Esteban
Published: November 2024

Apresentação à edição “O insólito ficcional da tela aos livros, dos livros à tela: adaptações, recriações, traduções, menções”
EPISTEMOLOGICAL PERSPECTIVE AND DISCURSIVE CONSTRUCTION IN QUALITATIVE RESEARCH: CRYSTALLIZATION OF DATA
Authors: Peixoto Rafaela Araújo Jordão Rigaud
Published: November 2024

This paper aims at discussing some aspects related to the epistemological perspective of qualitative research, as well as the discursive construction process during this type of research. To this end, this paper discusses: (i) the relationship of participants with the researcher in the context of the research, including the due ethical positioning; (ii) the context of data generation; (iii) the profile of respondents and the research situation; and (iv) the visual map of the main topics reported in the interviews. In this sense, it is argued how principles of qualitative research are developed among the several variables present at the time of data generation, especially in relation to intercultural imbrications. It is hoped that the discussions addressed in this paper may contribute to increasing awareness on the relevance of considering the crystallization of data (qualitative aspects) when dealing with investigations involving human beings; and can be used as input for students to envision a comprehensive scope of the qualitative research planning.
VÍTIMAS E ABUSADORES: A CONSTRUÇÃO DO DISCURSO DO MOVIMENTO “ESCOLA SEM PARTIDO” SOBRE A RELAÇÃO PROFESSOR/ALUNO
Authors: De Souza Talita Maria
Published: November 2024

Este artigo tem por objetivo analisar o discurso do movimento conservador brasileiro  Escola Sem Partido (ESP), a partir de trechos de alguns dos textos organizados em seu portal online oficial, estudado entre os anos de 2019 e 2022. Nosso objetivo com a escolha das sequências discursivas retiradas do site foi mostrar como a construção dos sentidos da palavra “professor” foi feita. Para essa análise, utilizamos o instrumental teórico da Análise de Discurso Materialista (AD), buscando explicitar a produção discursiva do movimento e tentando desconstruir os efeitos de evidência por eles formulados. A leitura aqui apresentada mostrou como os sentidos mobilizados pelo movimento rompe rotinas de memória até então existentes e tenta sedimentar no imaginário coletivo novos sentidos para “professor” e “ensino”, usando para isso uma aproximação entre o trabalho docente e o abuso sexual.
O GÊNERO DISCURSIVO TEXTUAL MAPA: UM OLHAR LINGUAGEIRO SOBRE A CARTOGRAFIA ESCOLAR
Authors: Lima Jean Cássio , Ribeiro Luiz Antônio
Published: November 2024

Já há algum tempo vem se ampliando o debate a respeito de notícias falsas e discursos tendenciosos sendo veiculados nas mídias. Essa é uma discussão que passa pelo entendimento dos gêneros discursivos e dos gêneros textuais ao se considerar seu caráter enunciativo e sociodiscursivo. Acontece que muitas vezes os mapas aparecem como parte dos textos com notícias falsas ou tendenciosas, podendo eles mesmos ser os veiculadores dessas notícias. Mas, por serem erroneamente considerados textos puramente técnicos, passam pelo leitor de forma menos crítica do que o texto escrito. Diante disso, esse trabalho tem por objetivo discutir os mapas como gêneros discursivos e textuais. Para isso, foram analisados dois mapas em livros didáticos de Ensino Médio em circulação por escolas públicas brasileiras. Como resultado discute-se a necessidade de um letramento cartográfico nas escolas, a partir das reflexões da Cartografia Escolar, como meio de tornar a sociedade mais crítica na leitura de textos do gênero mapa.
ECOS DA SUBMISSÃO:A NARRATIVA DA OPRESSÃO DA MULHER NOS CONTOS DE MOACYR SCLIAR EM “AI, MÃEZINHA QUERIDA” E “HISTÓRIA PORTO-ALEGRENSE”
Authors: Quevedo Oppelt Camila , Avila Neto de Farias Ariane
Published: November 2024

A história das mulheres é marcada por sua subjugação e marginalização; diante do homem, senhor do espaço público, o feminino é relegado exclusivamente às atividades reservadas ao local privado - cumprindo os papéis de esposa e mãe. À vista do local a elas designado, a impossibilidade de questionamentos acerca das escolhas masculinas, foi o único caminho viável. Nesse sentido, o presente artigo visa analisar a construção das personagens-narradoras dos contos “Ai, mãezinha querida” e “História porto-alegrense”, publicados na obra O anão do televisor (1979), de Moacyr Scliar. Objetiva-se, com isso, demonstrar que as personagens de Scliar aqui analisadas são sujeitos silenciados frente aos valores de uma sociedade calcada nos princípios do patriarcado, em valores que privilegiam o masculino, de maneira que lhes é negada uma real escolha sobre o seu próprio destino, sua própria história, estando essa sempre amarrado ao do homem. Para tanto, a discussão partirá das contribuições teóricas de Simone de Beauvoir (2009), Teresa de Lauretis (1990) e Rita Schmidt (2012).
TEXTOS EN FUNCIÓN CRÍTICA
Authors: Croce Marcela
Published: November 2024

Presentación
Território e territorialidade quilombola: uma análise socioetnocultural da produção de alimentos e das festas, folias e rezas
Authors: Santos Hélio Rodrigues dos , Ferreira Ana Tereza Ramos de Jesus , Moreira Geraldo Eustáquio
Published: November 2024

A pesquisa buscou abordar as práticas socioetnoculturais e a centralidade do território e territorialidade para a constituição da identidade quilombola na Comunidade Quilombola Kalunga Ema, no estado de Goiás. No intuito de atingir tal objetivo, nos propusemos a discutir o conceito de território para a constituição da identidade quilombola e, ainda, compreender as práticas socioetnoculturais quilombolas em relação à produção de farinha, de secagem de carne e das festas religiosas. O estudo é de cunho qualitativo e exploratório; os instrumentos metodológicos foram a pesquisa bibliográfica e a documental; a observação participante; o registro fotográfico e conversas informais.  As informações coletadas foram interpretadas observando a metodologia da Teoria da Psicologia Histórico-Cultural. Os achados na investigação demonstraram que a Comunidade Quilombola Kalunga Ema ainda utiliza conhecimentos seculares na produção de farinha, na secagem de carne e das festas religiosas. Tais considerações ratificam a importância deste estudo, pois este conhecimento, até então transmitido de geração para geração de maneira oral, também precisa ser preservado como escrita. Desta forma contribuímos para a preservação de nossa cultura, que em muitos aspectos foi extremante negligenciada no trato do conhecimento da população negra e indígena.
Trajetória de vida e identidade para duas mulheres negras, mãe e filha, do Quilombo Manoel do Rego, Canguçu/RS
Authors: Spolle Marcus Vinicius , Soares Nara Beatriz Matias
Published: November 2024

Esse artigo busca fazer uma conexão com minha dissertação que está em desenvolvimento, onde a linha de pesquisa são os quilombolas, mais precisamente adota uma perspectiva geracional onde os sujeitos são pais e filhos. Aqui fiz um recorte para mulheres, visto ser um estudo de gênero. Assim sendo, metodologicamente é uma pesquisa qualitativa, com entrevistas semiestruturadas com duas mulheres do Quilombo Manoel do Rego com o intuito de saber suas trajetórias de vida e como elas vêem suas identidades.
On the Russian BRICS Chairmanship Agenda
Authors:   Institute of Europe, Russian Academy of Sciences, Roginko Sergey
Published: November 2024

The paper examines the feasibility of including issues of countering the EU initiative to introduce a transboundary carbon tax (CBAM) into the agenda of the Russian BRICS presidency in 2024. The economic and geopolitical risks of BRICS countries and the Global South in connection with introduction of this initiative are analyzed. Forecasts are given for financial losses for the export industries of these countries within the framework of CBAM in the coming years and for the period up to 2040. An analysis is carried out of the positions on this issue of individual BRICS countries, BRICS as an organization, the BASIC group, as well as Turkey, African countries, as well as countermeasures, adopted by them at the level of the WTO and global climate negotiations within the framework of the UNFCCC and the Paris Agreement. Recommendations are given on specific steps necessary to intensify BRICS activities in this direction during the Russian BRICS Chairmanship in 2024.
Parliament election in Belarus as an element of constitutional reform
Authors:   Institute of Europe, Russian Academy of Sciences, Mezhevich Nikolai , Shimov Vsevolod ,   Institute of Europe, Russian Academy of Sciences
Published: November 2024

On February 25, 2024, a single voting day took place in Belarus, during which new members of the House of Representatives of the National Assembly, as well as deputies of local councils, were elected. The campaign should be considered in the context of constitutional reform in Belarus, as well as a preparatory stage for political transition, which can happen within 10 years. The authors analyze changes in the party-political system of the Republic of Belarus, the international aspect of elections and reaction of external players in the West and the East.
Presidential Elections in Finland 2024
Authors:   Institute of Europe, Russian Academy of Sciences, Plevako Natalia
Published: November 2024

The article analyzes the course and results of the presidential elections in Finland in January- February 2024. The results of voting for candidates from the country's largest political forces, the reasons for their successes and failures are presented. The main attention is paid to the participants of the second round: A. Stubb and P. Haavisto. The author comes to the conclusion that the presidential elections revealed a consolidated approach of various political forces to the problems of foreign policy and security.
Clusters of successes and problems: results of the European cluster conference
Authors:   Institute of Europe, Russian Academy of Sciences, Kotov Alexander
Published: November 2024

The annual European cluster conference took place in Brussels on May 7-8, 2024. It was organized by the European Commission in cooperation with the Belgian Presidency of the Council of the EU and support of the European Platform for Cluster Cooperation. The main attention was paid to the role of clusters in ensuring the Single Internal Market and increasing the competitiveness of the EU. A special feature of the conference was a debate on the practical role of clusters in developing the economic and political space of the EU in the next five-year political and economic cycle. The author analyzes main ideas of the conference and shows that in development of management priorities of the European Commission for 2024-2029 cluster policy will play a significant role in promoting industrial development priorities in the EU.
On results of Xi Jinping's visit to Serbia in the context of "shuttle diplomacy"
Authors:   Institute of Europe, Russian Academy of Sciences, Entina Ekaterina
Published: November 2024

In early May, the Chinese leader visited Europe. Meetings were held with E. Macron, V. Orban and A. Vucic. Xi Jinping managed to present to each of his interlocutors a mutually beneficial political format of the meeting. Visits laid the foundation for expanding the presence of Chinese production facilities and capital in Europe, despite the policy of decoupling with China, conducted by both the United States and the EU. A special feature of the tour was the meeting with the Serbian leader. The scale of cooperation achieved in recent years and the signed agreements indicate that the PRC no longer plays a complementary role for Serbia. Beijing has become an independent, systemic factor in Serbia's domestic and international development strategy.
Change of First ministers in Scotland and Wales – a new crisis of power in a country
Authors:   Institute of Europe, Russian Academy of Sciences, Okhoshin Oleg
Published: November 2024

In May 2024, J. Swinney became First Minister of the devolved government in Scotland after H. Yousaf had resigned due to the prospect of a vote of no confidence, which was being prepared by opposition parties in Holyrood. The reason for parliamentary confrontation was the breaking of coalition agreement between the ruling Scottish National Party (SNP) and the Greens by H. Yousaf. In the same month, Plaid Cymru had caused a political crisis in Wales by breaking partnership agreement with the Labor government. It was due to the scandals that discredited the First Minister of Wales and the leader of Welsh Labour W. Gething. The crisis of power in Scotland and Wales shows how fragile cross-party consensus can be due to misaligned regional establishment interests. The unstable political situation in the Celtic regions may affect the balance of political forces there in the general election on July 4, 2024.
Foreign policy consensus against the backdrop of the UK election campaign
Authors:   Institute of Europe, Russian Academy of Sciences, Godovanyuk K.
Published: November 2024

On July 4, a general election is due to take place in Britain, in which the Labour party will predictably sweep the board. In the election campaign of leading political forces issues on the international agenda fade into the background, which reflects the interests of electorate. A change in the ruling cabinet will hardly be a U-turn from the current foreign policy. The strategic guidelines as set by the Conservatives during their 14 years in power are likely to persist including the building of a new model of relations with the EU, protracted confrontation with Russia, special role in European security, but also an ambivalent policy towards China with minor variations.
The change of prime ministers in the Republic of Ireland is an indicator of the government crisis
Authors:   Institute of Europe, Russian Academy of Sciences, Okhoshin Oleg
Published: November 2024

On March 20, 2024, the Prime Minister of the Republic of Ireland L. Varadkar resigned amid the failure of constitutional referendums to change the legal language of marriage and family responsibilities. On March 24, 2024, the ruling Fine Gael party elected 37-year-old S. Harris as its new leader, who will become the youngest head of government. The change of prime ministers indicates a growing crisis in the political course of the coalition government. In these conditions, the opposition party Sinn Féin despite having supported the referendums has a greater chance of becoming the favorite in the 2025 general elections if it builds its election campaign correctly.
Requiem or Ode to Joy: on the economic future of the EU in 2024-2029
Authors:   Institute of Europe, Russian Academy of Sciences, Kotov Alexander , Vasilchenko Alexander ,   Institute of Europe, Russian Academy of Sciences
Published: November 2024

The next institutional cycle of the EU begins in a period of unprecedented uncertainty in global economy with a number of large-scale and intertwined problems of the European economic space. The authors consider possible economic and political directions in the activities of the new composition of the European Commission and prospects of adapting the EU standard to the rapidly changing geoeconomic environment. The article analyzes position of European countries in KOF globalization index. The authors assess key positive and negative factors of investment attractiveness of the Union. Main future measures in economic policy will be associated with activation of investment policy, introduction of special instruments to support companies in their upgrading of the green course policy, and reduction of internal barriers in the Single market. Significant risks along this path are associated with the political sphere whose actors may not cope with coordination of various bureaucratic interests.
Elections in Saxony and Thuringia: A Test of Stability of Germany's Party-Political System
Authors:   Institute of Europe, Russian Academy of Sciences, Belov Vladislav
Published: November 2024

On September 1, 2024, elections were held to the state parliaments (Landtage) in two Eastern German states: Saxony and Thuringia. As expected, the “protest” parties "Alternative for Germany" (AfD) and "Sahra Wagenknecht Alliance for Reason and Justice" achieved significant results. Meanwhile, the parties that make up the federal government received historically low support. The author analyzes implications of these outcomes for the party-political system of the Federal Republic of Germany and assesses prospects of governments’ configurations in Saxony and Thuringia.
Evaluación participativa de la sustentabilidad en unidades productivas campesinas de Tinjacá, Colombia
Authors: Pérez-Alarcón Cristian Alejandro , Rodríguez-Robles Ulises , Reyes-Ardila Wendy Lorena , González-Santos Wilson , Rosales-Adame Jesús Juan , Fontalvo-Buelvas Juan Camilo
Published: November 2024

Agriculture practiced at a family scale is a key production strategy for reproducing agroecological practices and ensuring food security and sovereignty. Often, small-scale production systems have notable strengths that deserve to be replicated but may also present multidimensional shortcomings that threaten their sustainability. In this context, the objective of this study was to evaluate, through a participatory approach, the sustainability of Small Farmers’ Production Units (SFPU) of Tinjacá (Boyacá), in central Colombia. The methodological strategy of the study was guided by the MESMIS Program (Spanish acronym for Indicator-based Sustainability Assessment Framework). The main results showed that the SFPUs in the municipality of Tinjacá have medium sustainability (ÍGS=3.1) with the highest rated environmental dimension (3.4) compared to the social (3.0) and economic (3.0) dimensions. In general, technical recommendations focus on building schools in small-scale farming communities, redesigning land parcels, and adopting agroecological practices. Collaborative efforts facilitated the collective development of viable technical solutions aimed at enhancing farm sustainability and improving the quality of life of farming families.
РУКОПИСНЫЙ ЦИКЛ РАННЕСТАРООБРЯДЧЕСКИХ СОЧИНЕНИЙ ИНОКА АВРААМИЯ И ДЬЯКОНА ФЕДОРА: НЕКОТОРЫЕ ВОПРОСЫ ПРОИСХОЖДЕНИЯ, СОСТАВА, БЫТОВАНИЯ И МЕСТА В ПОЛЕМИКЕ
Authors: Л.Д. ДЕМИДОВА
Published: November 2024

Статья посвящена выявленному в рукописях XVII-XIX вв. устойчивому циклу из пяти сочинений раннестарообрядческих авторов - инока Авраамия и дьякона Федора. Хотя сочинения цикла достаточно хорошо знакомы исследователям, ранее признавалась связь только между отдельными его частями, принадлежащими тому либо другому полемисту. В работе показано, что эта связь не ограничивается фактом принадлежности авторов к числу идейных основателей старообрядческого движения. Все сочинения связаны как тематически, так и текстуально, а главным связующим звеном между ними является Челобитная инока Авраамия (1670 г.), остальные произведения дополняют и иллюстрируют ее основные идеи. На основании изучения рукописей цикла и идейного содержания текстов сделан вывод о раннем (конца XVII в.) его происхождении: предположительно он появился в московской старообрядческой общине через некоторое время после казни инока Авраамия (1672 г.).

The task of studying both individual works belonging to the founders of the Old Believer movement, and the totality of the heritage of each of them, still remains relevant. The manuscript surroundings of specific polemical works, as well as the origin and evolution of the collections in which they have survived until nowadays, make it possible to understand better the origin of the author’s text, and in some cases, to trace the stages and methods of work of the Old Believer ideologists. Preliminary results of the search and work on the systematization of the copies of one of the fundamental works for the Old Believer tradition - the Petition of the monk Avraamii (d. 1672) - allow us to state quite definitely that in a number of cases the manuscript surroundings of the Petition has a stable character, repeating from copy to copy. One of the versions of such surroundings is a sequence of five works by the monk Avraamii and his associate and co-author deacon Fyodor. In addition to the general handwritten history (at least 10 manuscripts are known), the sequence of five works has a well-defined logic of construction. Previously, the thematic connection was noted only in relation to its individual parts belonging to one or another polemist. However, a comparative analysis shows that all five works of the sequence are connected and complement each other, while the Petition of Avraamii is the central, organizing text. The existence of the five-part manuscript sequence by the end of the 17th - early 18th century is confirmed by the dating of the earliest manuscripts containing it. However, the monk Avraamii himself could hardly have been its author. Most likely, the closest associates of the monk could have compiled the sequence, and this happened not before the completion of work on the Petition, or even after his death, in the 70-90s of 17th century.
A Man of an Epoch in Domestic Science: To the 100th Anniversary of Academician Platon Kostyuk
Authors:   O.O. Bohomoletz Institute of Physiology, NAS of Ukraine, Sagach V.F. , Tkachenko M.M. ,   O.O. Bohomoletz Institute of Physiology, NAS of Ukraine
Published: November 2024

This article highlights the life and contributions of Academician Platon Kostyuk, a prominent figure in neurophysiology, celebrating his groundbreaking work in cellular and molecular physiology.
The Role of TRPV1 and Glutamate Receptors in the Synaptic Activity of Lamina X Neurons of the Rat Spinal Cord
Authors:   Bogomoletz Institute of Physiology of NAS of Ukraine, Kyiv, Ukraine, Koroid K.V. , Blashchak I.O. ,   Bogomoletz Institute of Physiology of NAS of Ukraine, Kyiv, Ukraine, Romanenko S.V. ,   Bogomoletz Institute of Physiology of NAS of Ukraine, Kyiv, Ukraine
Published: November 2024

This study is aimed at understanding the mechanisms of nociceptive signaling in lamina X of the spinal cord, which are involved in the regulation of pain sensations. First, tetrodotoxin, which blocks action potentials, was applied to the system, which made it possible to isolate miniature synaptic activity (mEPSCs). After that, they added pidal, an agonist of TRPV1 receptors, which caused a significant increase in the frequency and amplitude of mEPSCs. Against the background of tetrodotoxin, the effect of capsaicin was biphasic: at first, the frequency of events increased sharply, after which it gradually decreased, but the amplitude increased. A control, without tetrodotoxin, application of capsaicin also caused an increase in synaptic activity, but this effect was not biphasic. Additional blockade of NMDA receptors (AP-5) partially reduced capsaicin-induced activity, while an AMPA receptor blocker (CNQX) almost completely abolished it, suggesting a critical role of glutamate receptors in maintaining this activity. The obtained results emphasize the importance of TRPV1 receptors in central sensitization and the possibility of its regulation, which opens new ways of modulation of chronic pain.
ntensity of Nitroso-Oxidative Processes in the Oral Fluid in Children With a Combination of Latent Iron and Mild Iodine Deficiency
Authors:   Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Zaiats O.V. , Voronych-Semchenko N.M. ,   Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Kryvenkyi Т.R. ,   Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine
Published: November 2024

Proper supply of bioelements that participate in physiological processes is especially important in childhood, because it significantly affects for the formation of the hormonal profile. The prevalence of dental pathology among schoolchildren reflects the priority of early diagnosis and thorough prevention of pathological processes. In order to find out the risks of dental health disorders, the intensity of nitroso-oxidative processes in the oral fluid of children (boys and girls aged 6-11 and young men and girls aged 12-18) with combined latent iron and mild iodine deficiency was studied and in conditions of sufficient supply of trace elements (control group). As a result of the study, the activation of the peroxidation processes of proteins (the level of products of oxidative modification of proteins increases by 87.3% - 3.3 times) and lipids (the content of diene conjugates increases by 62.7% - 12.4 times) in case of imbalance of antioxidant protection of oral fluid (inhibition of SOD by 20.4-30.7%, activation of glutathione peroxidase by 92.0-93.3%) compared to data in healthy teenagers. The development of iron and iodine deficiency is accompanied by an 8.3-fold increase in NO2 - content, a 3.3-fold increase in the amount of NO2 - and NO3 - in the oral fluid of boys, and a 2.5-11.4-fold increase in the concentration of peroxynitrite in all schoolchildren compared to controls. An increase in H2S content in the oral fluid was also found in girls (by 25.6% compared to the values of the control group). The level of oxidative processes is higher in younger schoolchildren (ages 6-11). With age, the intensity of oxidative stress decreases, but changes in the NO metabolism system increase, especially for girls (cytotoxic peroxynitrite and H2S accumulate in the oral fluid). Therefore, it is possible to assert a high probability of the development of nitroso-oxidative stress in the conditions of a combination of iron and iodine deficiency already at the stage of preclinical changes, which can increase the risks of developing dental pathology.
Energy Metabolism in the Liver of Rats With Rotenone-Induced Parkinsonian Syndrome Under the Influence of Methanindiazenone
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Shtanova L.Ya. , Veselsky S.P. ,   Taras Shevchenko National University of Kyiv, Ukraine, Yanchuk P.I. ,   Taras Shevchenko National University of Kyiv, Ukraine, Tsymbalyuk O.V. ,   Taras Shevchenko National University of Kyiv, Ukraine, Moskvina V.S. ,   Bogomolets National Medical University, Kyiv, Ukraine, Shablykina O.V. ,   Taras Shevchenko National University of Kyiv, Ukraine, Reshetnik E.M. ,   Taras Shevchenko National University of Kyiv, Ukraine, Kravchenko O.V. ,   Bogomolets National Medical University, Kyiv, Ukraine, Khilya V.P. ,   Taras Shevchenko National University of Kyiv, Ukraine
Published: November 2024

Parkinson’s disease (PD) is symptomatically characterized by motor disorders in the human body, which are associated with the degeneration of dopamine neurons in the substantia nigra of the midbrain. It is widely recognized that mitochondrial dysfunction occurs in dopaminergic neurons, leading to their death and the development of this pathology. Recently, benzodiazepine derivatives have been found to have a neuroprotective effect against damage of dopaminergic neurons in an experimental model of Рarkinsonian syndrome (PS). The aim of this study was to investigate the effect of a novel molecule, named methanіdiazenone, on energy metabolism in the liver of rats induced by rotenone. To achieve the set goal, the concentration of ATP, ADP, AMP, hypoxanthine аnd xanthine were determined in the bile samples of rats with PS by the method of thin-layer chromatography. The obtained data indicate that under the influence of rotenone compared to the control values the content of ATP in bile decreased by 40%, while the levels of AMP, xanthine and hypoxanthine, on the contrary, increased by 87,5%, 55,6%, and 25%, respectively. Our findings suggested that the ratio of AMP/ATP, which is an important indicator of the functional state of mitochondria, under the influence of rotenone increased by 200% compared to the control. Metanindiazenone in a dose of 1,0 and 2,0 mg/kg normalized all studied parameters of purine metabolism. The presented results show that methanindiazenone significantly improves purine metabolism in the liver of rats with PS induced by rotenone, indicating the normalization of mitochondrial function in hepatocytes. Thus, methanindiazenone may be recommended for clinical trials regarding its use in combination with other drugs to treat Parkinson’s disease and possibly other neurodegenerative diseases, in which mitochondrial dysfunction occurs.
Supporting the Well-Being of Children and Youth With Special Health Care Needs: NASEM Proceedings
Authors: Rosenberg Abby R. , Pickles Diane M. , Harris Debbi Simmons , Lannon Carole M. , Houtrow Amy , Boat Thomas , Ramsey Bonnie
Published: November 2024

Children and youth with special health care needs (CYSHCN) are living longer than ever. These advances come with a price: Patients, families, communities, and systems must absorb the challenges of chronic caregiving, including protracted stress and poor mental health. In 2023, the National Academies of Science, Engineering, and Medicine convened thought-leaders for conversations about supporting the emotional well-being of CYSHCN and their families. Invited panelists included 2 parents and 3 academic pediatricians. Parents suggested opportunities for clinicians and systems to better support CYSHCN. Clinicians described work focused on: Individual patient- and family-level resilience: Defined as a process of harnessing resources to sustain well-being in the face of stress, resilience is learnable. Programs that teach people to identify and bolster “resilience resources” show promise in improving child and caregiver mental health;Clinician- and practice-level provision of care: Individual-level interventions are only effective if clinicians know when and how to deliver them. Hence, the American Board of Pediatrics created and demonstrated the success of a “roadmap” to support routine screening for and discussion of social and emotional health needs; andSystems-level barriers: Even with patient-level programs and clinician-practice guidance, unmet social and mental health needs persist.

Accessing and coordinating services is difficult, may not be covered by insurance, and historically marginalized populations are the least likely to benefit. Together, the panel underscored a critical fact: We cannot optimize child and family well-being without focusing on patients, caregivers, clinicians, and systems.
Karaciğer Sirozunda Yorgunluk, Kas Kuvveti ve Kas Oksijenasyonu İlişkisi
Authors: Taşkın Gürel Bilge , Saglam Melda , Polat Özer Yasemin , Okyar Baş Arzu , Keskin Onur , Doğrul Ahmet Bülent , Cankurtaran Mustafa , Vardar Yaglı Naciye
Published: November 2024

Amaç: Çalışmamızın amacı; karaciğer sirozu olan hastalarda yorgunluk şiddeti, kas kuvveti ve kas oksijenasyonu arasındaki ilişkinin incelenmesidir.
Yöntem: En az bir senedir karaciğer sirozu tanısı ile takip edilen 35-75 yaş aralığındaki hastalar çalışmaya dahil edildi. Katılımcıların Model for End-Stage Liver Disease (MELD) ve Child-Pugh-Turcotte (CPT) skorları hesaplandı. Olguların yorgunluk düzeyleri Yorgunluk Şiddet Ölçeği ile değerlendirildi. M. Quadriceps kas kuvveti dijital el dinamometresi ile ölçüldü. Kas oksijenasyonu, Yakın Kızılötesi Spektroskopisi modeli kullanılarak değerlendirildi. Olguların istirahatte m. vastus medialis kasına sabitlenen monitör kas oksijenasyonu ölçümü için kullanıldı.
Bulgular: Çalışmamıza 25 karaciğer sirozu hastası (12 K, 13 E) dahil edildi. Olguların MELD ve CPT skorları ile yorgunluk şiddeti, kas kuvveti ve oksijenasyonu arasında bir ilişki yoktu (p>0,05). Karaciğer sirozu hastalarının yorgunluk şiddetleri ile m. quadriceps kuvveti ve kas oksijenasyonu arasında negatif yönde orta düzeyde ilişki bulundu (r=-0,429, p= 0,032; r=-0,468, p=0,018).
Sonuç: Karaciğer sirozu hastalarında hissedilen yorgunluk şiddeti, kas kuvveti ve kas oksijenasyonu ile ilişkilidir. Çalışmamızın sonuçlarına göre, daha yüksek kas kuvveti ve kas oksijenasyonu, daha düşük şiddetli yorgunluğa işaret etmektedir. Çalışmamız, kronik karaciğer hastalarının egzersiz kapasite ve kas kuvvetinin artırılması, fiziksel aktivite seviyelerinin geliştirilmesi ve yaşam kalitesine olumlu etkiler sağlayacak fizyoterapi ve rehabilitasyon programlarının planlanmasına katkı sağlayacaktır.
Metaphorical perceptions of university students experiencing Kahramanmaraş Pazarcık and Elbistan earthquakes on the concept of 'earthquake': case of physiotherapy and rehabilitation department
Authors: Kocamaz Deniz , Yılmaz Ramazan Cihad , Dinler Elif , Büyükturan Öznur , Yakut Yavuz
Published: November 2024

Purpose: This study was carried out to determine the metaphorical perceptions of the earthquake of Physiotherapy and Rehabilitation students who experienced the Kahramanmaraş, Pazarcık and Elbistan earthquakes.
Methods: In the study, phenomenology research design based on qualitative research approach was used. The participants of the research consist of 120 students who experienced the February 6
Kahramanmaraş Pazarcık-Elbistan earthquakes, studying at Hasan Kalyoncu University Physiotherapy and Rehabilitation Department in the 2022-2023 academic
Results: The students reproduced a total of 51 metaphors. As a result of the analysis of these metaphors, 9 categories were determined. It is seen that a large number of metaphors have been produced in this study about ‘doomsday’, ‘death’, ‘helplessness’ and ‘disaster’. The most metaphors were produced in the categories of ’End of life’ (f:31), ‘Natural event’ (f:20), ‘Despair-related’ (f:18) and ‘State of Health’ (f: 16).
Conclusion: It is seen from the metaphors that Kahramanmaraş Pazarcik and Elbistan earthquakes have more negative effects on the minds of Physiotherapy and Rehabilitation students. Since the impact of the earthquake will continue for some time on the educational life and psychosocial state of the students, it is important to establish a professional team and their supporting. Putting a course in the curriculum specifically in the ‘earthquake’ plan and in the ‘disaster’ plan in general may contribute to their being able to get through this process with less impact.
Blood parameter examination in mountain quails (Oreortyx pictus Douglas, 1829) at the end of the breeding season
Authors: Gál János , Szabó Bernadett , Csatári Dóra , Marosán Miklós , Sós Endre , Sós-Koroknai Viktória , Hoitsy Márton , Papp Antal , Nógrádi Anna Linda , Tóth Tamás , Ziszisz Árisz , Vincze Zoltán , Mándoki Míra , Vajdovich Péter
Published: November 2024

In this publication various serum biochemistry and haematology parameters were determined from blood samples obtained from captive adult individuals of an exotic quail species, the mountain quail (Oreortyx pictus, Douglas, 1829). Venipuncture was performed in the second half of the breeding season from six roosters (males) and seven hens (females). During the examination, in addition to the haematological elements, basic parameters of serum enzyme levels, the products of protein metabolism, uric acid and the most important ions were monitored. The results are presented as a reference in future diagnostic tests for certain diseases. The blood parameters of the bird species examined in this study have not yet been published earlier.