bluuebunny/crossref_metadata_2025 huggingface dataset:
Pratiques numériques, perception de la violence en ligne et victimation chez les étudiants
Authors: Berthaud Julien , Blaya Catherine
Published: December 2021

La recherche en éducation sur la violence entre pairs au moyen des technologies d’information et de communication, ou cyberviolence, se développe depuis plus d’une décennie à l’étranger, et plus récemment en France. Le public étudiant demeure peu étudié malgré une continuité du risque apparente. Cet article2 s’attache à évaluer l’ampleur de la victimation3 en ligne chez des étudiants français en lien avec leur utilisation des technologies et leur propre opinion sur ces thématiques. Les résultats tendent à confirmer le risque chez les étudiants d’être concernés par la cyberviolence notamment au regard de leurs pratiques numériques. Par ailleurs, des écarts de représentation entre conceptualisations scientifiques et perception des sujets enquêtés ressortent et entrent en résonnance avec les débats sémantiques et méthodologiques indissociables de cet objet de recherche.
Définir les rituels à l’école maternelle : un paradoxe institutionnel, pédagogique et scientifique
Authors: Briquet-Duhazé Sophie
Published: December 2021

Le terme « rituels » désigne les règles, les habitudes qui organisent la vie de la classe. Ils sont répétés quotidiennement avec un objectif général qui est celui de la conquête de l’autonomie. Ces rituels sont établis en fonction de plusieurs paramètres : l’espace et le temps, des compétences et des objectifs précis, un matériel à manipuler. Leur répétition s’appuie sur des activités, des mises en situation variées et évolutives où chaque élève contribue à la construction du groupe. Nous nous proposons de questionner ici le paradoxe qui existe entre l’usage massif de ce terme à l’école maternelle et sa quasi-inexistence dans la documentation qu’elle soit officielle, pédagogique ou scientifique.
Les rituels dans la classe de Claire : d’une pédagogie inspirée de TEACCH à celle inspirée du Floor Time : quels changements ?
Authors: Odier-Guedj Delphine
Published: December 2021

Dans ce texte, j’aborderai le rituel comme « un mouvement corporel avec un début, une fin et une direction précise. Il assigne ainsi une position déterminée aux participants. Les mouvements du corps pendant le rituel provoquent des émotions qui sont par la suite, à l’origine d’une modification de ce rituel » (Wulf, 2003). L’objet de cet article est de questionner la double orientation « créer une stabilité » et « la mettre en mouvement » au travers de l’expérience d’une enseignante en classe spécialisée accueillant des élèves ayant un Trouble Envahissant du Développement (TED)2, accompagnée au long cours lors d’un de mes projets de recherche. Son changement de perspective d’enseignement, lorsqu’elle a quitté une pratique inspirée de l’approche TEACCH3 pour introduire du Floor Time dans sa pédagogie souligne, à plusieurs titres, un glissement de sens à propos des rituels. Après avoir brièvement présenté ce que sont les troubles envahissants du développement et les deux approches utilisées successivement par Claire, je développerai trois aspects liés à ces rituels : la mise en contrainte du corps de l’enfant, l’appropriation d’une temporalité interne, le cadre de l’apprentissage.
Les rituels : des espaces de marge pour construire sa place
Authors: Hatchuel Françoise
Published: December 2021

L’article distingue les rituels dits « de passage » des rituels d’interaction et des rituels religieux, tout en soulignant leurs points communs : efficacité performative permettant le lien et le passage (vers un nouveau statut, une nouvelle situation, un monde surnaturel) et espaces de marge qui les distinguent des procédures desubjectivantes. Après avoir repéré quelques travaux sur les rituels scolaires, l’auteure se centre, d’une part, sur les rituels d’interaction dans l’apprentissage, d’autre part sur les rituels de passage à l’âge adulte qui garantissent au jeune qu’il a une place dans la société adulte tout en lui offrant une protection pour vivre les émotions qui lui permettront d’occuper cette place. En lien avec la théorisation de la psychanalyste Piera Aulagnier, l’ensemble la conduit à proposer le terme d’« anthropologisation » pour définir le processus qui conduit l’enfant à prendre place dans la société des humains sans forcément savoir quelle fonction il y occupera (processus de socialisation).
Le sens des rites scolaires
Authors: Jeffrey Denis
Published: December 2021

Dans le cadre scolaire, nous nous intéressons aux rituels par lesquels les enseignants et les élèves se mettent en scène. En fait, un nombre impressionnant de rites, plus ou moins élaborés, plus ou moins codés, plus ou moins maîtrisés, rythment et ordonnancent la vie scolaire des élèves et des enseignants. La pédagogie, depuis ses débuts, ne vise-t-elle pas à entretenir et à maintenir un certain ordre scolaire en fixant les comportements des élèves et des enseignants. Un enfant devient élève, en fait, en adoptant les comportements très ritualisés qui le font élève. On reconnaît aussi un enseignant aux rites qui le font enseignant. C’est dire qu’il y a des gestes, des savoir-être, des savoir-faire, une langue, un style vestimentaire, en fait, une composition de soi, qui révèle un individu comme enseignant ou comme élève. Dans cet article nous nous intéressons à ces rituels qui créent des identités.
A Panel Regression Analysis to Determine Returns on Assets of Banks in Ghana
Authors: Quaicoe M.T. , Twenefour F.B.K. , Addor J.A. , Baah E.M.
Published: December 2021

This article aimed at examining the determinants of the returns on assets of banks using a panel regression analysis. The explanatory variables considered in the regression model were Capital Adequacy, Assets Quality, Management Quality and Liquidity Ratio. The effects of the explanatory variables on the returns on assets were explored by fitting a panel multiple regression model to the data. The results of the study show that the observed returns across the banks do not change over time, thus indicating that the series is stationary. There is evidence of significant differences across the banks considered for the study, hence the use of Random effects model. All the explanatory variables considered in the study including the intercept were found to have significant effects statistically on the returns on assets across the banks. About 73% of the variations in the returns on assets across the banks can be accounted for by the independent variables.
Efficacy of Seaweed Extract on Chilli Leaf Curl Virus
Authors: Sugandhika M.G.G. , Pakeerathan K. , Fernando W.M.K.
Published: December 2021

The important cash crop of Chilli’s (Capsicum annum L) production and yield is hampered by Chilli Leaf Curl Virus Disease (CLCVD) in Sri Lanka. To manage CLCVD several insecticides were promised against the vectors of CLCV. Indiscriminate use of insecticides created unwanted human health hazards. The current trends in plant pathology intend to boost the immunity of the host to increase the resistance against pathogens. Therefore, this study was conducted to investigate the efficacy of Sea-Weed Extract (SWE) to manage CLCVD. The chilli variety Vijaya was selected for this experiment with five treatments and a non-treated control, which were arranged in RBCD. Data on growth parameters, yield, aphid severity, and CLCV disease severity Index (DSI) were measured and subjected to ANOVA in SAS and Tukey's HSD multiple comparison test was used to identify the best treatment combination at P <0.05. The results showed that first application of Sea-Weed Extract (SEW) at 15 days after planting with subsequent application of SWE at 15 days interval + application of insecticides at 10-15 days interval (T4) significantly lowered the CLCV DSI of 40.24%, less aphid severity index of 5.16% with the highest chilli yield of 436.8 kg/ha. The investigation concluded that SWE induces plant immunity but no effect on vector control. Therefore, SWE with recommended insecticides is better to increase the immunity of plants for the effective management of CLCVD.
Growth and Yield Response of Chilli (Capsicum annum L) for the Combined Organic and Inorganic Fertilizer Application
Authors: Ruhunuge I.J.A. , Wijeratne A.W. , Wimalasiri E.M.
Published: December 2021

It is well known that the overuse of inorganic fertilizers has catastrophic impacts on forms of life and the environment. In chemical fertilizers, Nitrogen is one of the main elements that has a high leaching potency which leads to pollute both surface and groundwater resources. This study was carried out to identify the best organic and inorganic fertilizer combination that gives the highest yield in MI-Green. The treatments are 3 kg/pot cow dung (control 1), (T1), 2 kg/pot cow dung (control 2) (T2), 2 kg/pot cow dung + foliar urea spray (T3), 2 kg/pot cow dung + urea soil application (T4), 3 kg/pot cow dung+ foliar spray (T5) and 3 kg/pot cow dung + Urea soil application (T6). Results disclosed a significant effect (p<0.05) on growth and yield in T5. Hence, it can be concluded that 3kg/pot cow dung+ foliar spray combination can be used to improve the growth and yield of MI-Green chilli.
Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences
Authors: Tarsalainen Alina , Maman Yaakov , Meng Fei-Long , Kyläniemi Minna K , Soikkeli Anni , Budzyńska Paulina , McDonald Jessica J , Šenigl Filip , Alt Frederic W , Schatz David G , Alinikula Jukka
Published: December 2021

Somatic hypermutation (SHM) drives the genetic diversity of Ig genes in activated B cells and supports the generation of Abs with increased affinity for Ag. SHM is targeted to Ig genes by their enhancers (diversification activators [DIVACs]), but how the enhancers mediate this activity is unknown. We show using chicken DT40 B cells that highly active DIVACs increase the phosphorylation of RNA polymerase II (Pol II) and Pol II occupancy in the mutating gene with little or no accompanying increase in elongation-competent Pol II or production of full-length transcripts, indicating accumulation of stalled Pol II. DIVAC has similar effect also in human Ramos Burkitt lymphoma cells. The DIVAC-induced stalling is weakly associated with an increase in the detection of ssDNA bubbles in the mutating target gene. We did not find evidence for antisense transcription, or that DIVAC functions by altering levels of H3K27ac or the histone variant H3.3 in the mutating gene. These findings argue for a connection between Pol II stalling and cis-acting targeting elements in the context of SHM and thus define a mechanistic basis for locus-specific targeting of SHM in the genome. Our results suggest that DIVAC elements render the target gene a suitable platform for AID-mediated mutation without a requirement for increasing transcriptional output.
Nurses’ Caring Behavior Based on Personality in Indonesia: A Pilot Study for Better-Humanized Healthcare Services
Authors: Handayani Euis Trisnawati , Kuntarti Kuntarti
Published: December 2021

Background

Caring behavior is influenced by psychological factors, including the characteristics of personality. However, psychological test results for nurses’ recruitment are not optimal for nursing resource development. This study aimed to determine the relationship between personality characteristics and nurses’ caring behavior in hospitals.

Design and methods

A cross-sectional design was adopted involving 153 nurses of a private hospital in Jakarta selected by convenience sampling technique. Data were also collected from the Caring Behavior Inventory (CBI-24) and Myers-Briggs Type Indicators (MBTI) test results. Statistical analysis using the oneway ANOVA to identify differences in nurses’ CBI scores based on MBTI personality.

Results

The results study indicate that most of the nurses were traditionalists (75.16%), and the average CBI score (85.43±5.94) was equivalent to 85%, which means that nurses’ caring behavior was good. There were differences in the scores of caring behaviors among personality characteristics; however, these differences were not statistically significant (p=0.320; α=0.05). Furthermore, the post hoc test analysis showed that the conceptualizer nurses had the highest caring behavior score, while the experiencers had the lowest.

Conclusions

Personality characteristics, as measured by MBTI, are not related to the caring behavior of nurses. One possible reason for this result is that the MBTI does not specifically measure caring personality. Psychological tests on personality characteristics are used in career development and nurse placement. This study recommends that human resource management in healthcare use more specific tools to measure caring personality and psychological tests in healthcare staff recruitment for betterhumanized healthcare services.
The Effect of a Smartphone-Based Perioperative Nursing Intervention: Prayer, Education, Exercise Therapy, Hypnosis, and Music toward Pain, Anxiety, and Early Mobilization on Cardiac Surgery
Authors: Awaludin Sidik , Nurachmah Elly , Soetisna Tri Wisesa , Umar Jahja
Published: December 2021

Background

Cardiac surgery can elicit both physical and psychological responses. Prayer, exercise therapy, education, hypnosis, and music are expected to be able to overcome pain, anxiety, and immobilization in the cardiac surgery. This study was to create a smartphone-based peri-operative nursing intervention model that was able to reduce pain, anxiety, and increase early mobilization cardiac surgery patients.

Design and methods

This study consisted of three stages. The first stage was research and development, the second was true experimental design, and the third was cross sectional design. The samples size was 86 respondents. The intervention models for the treatment group comprised of a smartphone-based therapy of prayer, education, exercise, hypnosis, and music. The control group was given standard hospital intervention according to the clinical pathway.

Results

The majority of respondents were adults, male, high school graduate in the treatment group and bachelor graduate in the control group, CABG type of surgery, and having pain history. The intervention had a significant effect on reducing pain scale and anxiety level as well as increasing early mobilization (p<0.05). The intervention had a direct effect on pain and anxiety, but it had no direct effect on early mobilization. However, it gave indirect effect on early mobilization that was mediated by anxiety.

Conclusions

The models can be used by nurses to reduce pain, anxiety and to increase early mobilization on cardiac surgery patients.
Fathers’ Role in Sustainability of Exclusive Breastfeeding Practice in Post-Cesarean-Section Mothers
Authors: Budiati Tri , Setyowati S. , Adjie Seno , Gunawijaya Jajang
Published: December 2021

Background

The success of breastfeeding among post-cesarean- section mothers requires strong willingness and commitment, self-confidence, support from various professionals, and internal support (especially from their husband) and the belief and value of their family. Exclusive breastfeeding remains low in some cities such as in West Java, especially in post-cesarean-section mothers, who are influenced by certain factors. The purpose of this study is to identify husbands’ role and their support for post-cesarean-section mothers in exclusive breastfeeding.

Design and Methods

This study used a qualitative phenomenological approach. with a combination of different data collection techniques: focus group discussion and in-depth interviews. Twelve husbands of post-cesarean-section mothers participated in this study. Data were analyzed by thematic content analysis.

Results

Four themes were identified namely knowledge about exclusive breastfeeding, the role of the father during breastfeeding, the experience of the husband and the family in supporting breastfeeding, and Women's lack of knowledge, inconvenience due to pain as the most impending factors of exclusive breastfeeding.

Conclusion

Most fathers seem eager to be involved and assist their partners to give breastfeeding to their baby. Furthermore, adequate support from family members, health care professionals, and employers can enable fathers to encourage and help their partners initiate and maintain exclusive breastfeeding. Fathers’ emotional, practical, and physical supports are also important factors that promote successful breastfeeding and enrich the experience of mothers.
Chemical constituents and biological activities of essential oils of Amomum genus (Zingiberaceae)
Authors: Van Hong Thien
Published: December 2021

Amomum Roxb. includes the aromatic and medicinal plants native to tropical and subtropical Asia belonging to the family Zingiberaceae. Members of Amomum genus have been used for a long time in traditional medicine for the treatment of throat trouble, congestion of lungs, inflammation of eyelids, and digestive disorders, etc. Amomum essential oils have been studied for their chemical profiles in which limonene, allo-aromadendrene, 1,8-cineole, camphor, farnesyl acetate, α-pinene, β-pinene, caryophyllene, camphene, D-camphor, santolina triene, methyl chavicol, bornyl acetate, β-elemene, δ-3-carene, etc. were the major compounds. Furthermore, the oils extracted from Amomum plants have been reported to possess antimicrobial, antioxidant, insecticidal, larvicidal, cytotoxic, anti-scabies, and anti-inflammatory activities. This review focuses on the chemical constituents and biological activities of the essential oils isolated from the different plant parts of Amomum plants. The objective of the present review is to highlight therapeutic potentials and provide evidence for future medicinal applications of these species of genus Amomum.
An in vitro and in silico study of anti-dermatophytic activity of gossypol from fruits of Thespesia populnea (L.) Sol. ex Correa
Authors: Anuthara R , Midhun Sebastian Jose , Mathew Jyothis
Published: December 2021

Objective:

To isolate, purify, and characterize gossypol from the fruits of Thespesia populnea (L) Sol. ex Correa, test its anti- dermatophytic activity, identify its targets on the dermatophyte, and confirm the binding of gossypol with the fungal target by molecular docking study.

Methods:

Gossypol from Thespesia populnea was characterized by high performance liquid chromatography, liquid chromatograph- mass spectrometry, Fourier transform infrared spectroscopy, and nuclear magnetic resonance. The anti-dermatophytic activity of gossypol was tested against four different dermatophytes, viz. Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis, and Microsporum gypseum. Trichophyton mentagrophytes was selected for further studies. The inhibitory mode of action of gossypol on Trichophyton mentagrophytes was determined by analyzing the modulation of gene expression in various pathways of the dermatophyte.

Results:

Gossypol inhibited all the dermatophytes. The minimum inhibitory concentrations were 12.5 μg/mL for Trichophyton mentagrophytes and Microsporum canis and 25 μg/mL for Trichophyton rubrum and Microsporum gypseum. The minimum fungicidal concentrations were 50 μg/mL for Trichophyton mentagrophytes, 100 μg/mL for Microsporum canis and Trichophyton rubrum, and 200 μg/mL for Microsporum gypseum. Gossypol inhibited the mRNA expression of metalloprotease (MEP4) and isocitrate lyase (ICL). The binding of gossypol with the enzymes was confirmed by molecular docking studies. The best docking poses were found and the low binding energies were recorded with the two target enzymes.

Conclusions:

Gossypol is a potential antifungal agent and can be further explored as an anti-dermatophytic drug.
Ethyl acetate extract of Smilax glabra Roxb roots and its major active compound astilbin promote osteoblastogenesis in vitro by upregulating bone cell differentiation- associated genes
Authors: Nguyen Huyen T.T. , Nguyen Minh T.H. , Nguyen Thu X. , Pham Quan M. , Nguyen Ha X. , Nguyen Phuong T.M.
Published: December 2021

Objective:

To investigate the osteoblastogenic activity of the ethyl acetate (EtOAc) extract of Smilax glabra Roxb roots and its major active compound astilbin.

Methods:

Astilbin was isolated from EtOAc extract using silica gel chromatography combined with fraction crystallization. Chemical structure of astilbin was determined by analysis of the spectroscopic data in comparison with the literature. MTT method was used to detect the toxicity. Alkaline phosphatase (ALP) activity was determined by the spectrophotometric method at 405 nm using p-nitrophenyl phosphate as a substrate. Calcium deposition was stained with alizarin red-S, distained with cetylpyridium chloride, and quantified at 562 nm. In silico model for astilbin-ALP interaction was analyzed using AutoDock 4.2.6. The changes in expression of osteoblast differentiation related genes were determined using quantitative real-time PCR.

Results:

Both the EtOAc extract and astilbin had no toxicity toward osteoblast MC3T3-E1 cells at 5.0, 10, 25, and 50 μg/mL. At 25 μg/ mL, they enhanced ALP activity and mineralization of osteoblasts up to 30% and 55% for the EtOAc extract and 22% and 41% for astilbin, respectively. Molecular docking analysis of astilbin-ALP interaction revealed Arg167, Asp320, His324, and His437 were key residues participating in hydrophobic interaction; meanwhile, His434 and Thr436 residues were involved in hydrogen bond formation in the active site of human tissue-nonspecific ALP. Moreover, the expression level of genes opn, col1, osx, and runx2 were up-regulated in astilbin treated samples with the fold changes as 2.2; 3.7; 4.1; 2.3, respectively at 10 μg/mL (P<0.05).

Conclusions:

The EtOAc extract and its major compound astilbin exhibit osteoblastogenic activity by up-regulating important markers for bone cell differentiation. It could be a new and promising osteogenic agent with dual actions for therapeutic applications.
Body composition changes following chemotherapy for testicular germ cell tumor: obesity is the long-term problem
Authors: Takai Yuki , Naito Sei , Kanno Hidenori , Yamagishi Atsushi , Yagi Mayu , Sakurai Toshihiko , Nishida Hayato , Yamanobe Takuya , Kato Tomoyuki , Tsuchiya Norihiko
Published: December 2021

Metabolic syndrome is a long-term complication of systemic chemotherapy for testicular germ cell tumor (TGCT). It is believed to be caused by secondary hypogonadism or toxic medicines because of orchidectomy followed by systemic chemotherapy. In this study, changes in the body composition of patients over time were quantitatively analyzed up to 24 months after chemotherapy. This study retrospectively analyzed 44 patients with TGCT who underwent chemotherapy at our institution from January 2008 to December 2016. Subcutaneous and visceral fat areas and psoas and skeletal muscle areas were measured by computed tomography before and immediately after chemotherapy as well as 3 months, 6 months, 12 months, and 24 months after chemotherapy. The subcutaneous and visceral fat indices and psoas and skeletal muscle indices were calculated as each area divided by body height squared. The total fat area had already significantly increased 3 months after the initiation of chemotherapy (P = 0.004). However, it did not return to prechemotherapeutic levels even at 24 months after chemotherapy. The skeletal muscle area was significantly decreased at the end of chemotherapy (P < 0.001); however, the value returned to baseline within 12 months. In multivariable analysis, the prechemotherapeutic skeletal muscle index and number of chemotherapy cycles were independently associated with the reduction of skeletal muscle at the end of chemotherapy (P = 0.001 and P = 0.027, respectively). In patients with TGCT, skeletal muscle mass decreased during chemotherapy and recovered within 12 months, whereas fat mass progressively increased from the initiation of chemotherapy until 24 months after chemotherapy.
The Pattern and Factors Associated with COVID-19 Infection among Rheumatology Patients
Authors: Alfaris Huda , Alfaris Eiad , AlEnzi Fahidah , Irfan Farhana , El Kibbi Lina , Alrayes Hanan
Published: December 2021

Objectives:

The global coronavirus pandemic has led to a considerable concern among rheumatologists regarding the possible higher risk of infection and complications among their patients. The severity and outcome of coronavirus disease 2019 (COVID-19) infection among patients with rheumatic disease (RD) need to be studied to help guide physicians choose the best approach for different categories of patients. Therefore, we aimed to estimate the rate of COVID-19 infection among RD patients and to evaluate the risk factors and outcomes.

Methodology:

This study was a cross-sectional questionnaire-based study. A convenience and nonprobability sample of RD patients filled out the study questionnaire from October to November 2020. They were invited digitally through SurveyMonkey and were recruited from social support group sites of the Saudi Society of Rheumatology and the Charitable Association for Rheumatic Diseases. The Chi-square test, Mann–Whitney test, and Fisher's exact test were used as appropriate. Continuous data are expressed as the mean and standard deviation. A P < 0.05 was considered as statistically significant.

Results:

The study participants were composed of 530 RD patients. The ages of the participants ranged from 14 to 80 years, and women outnumbered men with a ratio 4.4:1 (329 female and 96 male patients). The rate of COVID-19 infection among the study population was 13.7% (n = 71). Previous comorbidities (liver disease and heart failure) were associated with higher risk of COVID-19 infection (P < 0.01 and 0.012) and worse outcome (P < 0.005).

Conclusion:

This study indicates a relatively high rate of COVID-19 infection among RD patients. Having comorbidities posed a significantly greater risk for contracting COVID-19 infection and developing worse outcomes. Therefore, close monitoring of patients with comorbidities such as liver and cardiovascular diseases is warranted.
A Cross-sectional Assessment of the Knowledge about Rheumatoid Arthritis among University Students in Saudi Arabia
Authors: Alenzi Fahidah , Al-Sheikh Haifa , Alaraj Khozama , Saeed Taeef , Alfedeah Raghad , Al-Anazi Reem , Alfawari Nawal
Published: December 2021

Background:

Rheumatoid arthritis (RA) is a chronic multisystem autoimmune inflammatory disorder characterized by inflammatory joint and extra-articular organ involvement including lung, eye, and heart that can lead to physical dysfunction and impaired quality of life.

Aim:

The aim of the study is to estimate the level of knowledge about RA and determine attitudes among university students and staff of Riyadh and to assess the limitations of this knowledge.

Materials and Methods:

A cross-sectional study was conducted at universities of Riyadh in Saudi Arabia. The study used a close-ended, interviewer-based questionnaire and includes 500 respondents from health and nonhealth college students and administrative staff.

Results and Discussion:

There were 404 (80.8%) females and 96 (19.2%) males and 65.5% were in the common age group of 18–24 years. The highest number of the participants (234, 48.6%) was from Princess Nourah University, and 53% of the participants were from nonhealth science colleges. 51.4% of the participants had a family member working or studying in a health-related field, and the level of knowledge of these participants about RA was 81 (31.5%). The age group that had poor knowledge of RA was between 31 and 40 years (including 83.3% of the participants). The participants from Princess Nourah Bint Abdulrahman University had good knowledge (31.7%) compared to participants from other universities. Finally, among gender groups, females had a better level of knowledge about RA (30.2%) compared to (69.8%) of males.

Conclusion:

Our study found that the level of awareness about RA in Riyadh is slightly lower than that observed in previous studies conducted in Saudi Arabia. This could be due to a lack of educational programs and awareness campaigns.
Advancing Nursing Practice in India
Authors: Kumar Rajesh , Rodney Tamar W.
Published: December 2021

Nurses, as key health personnel in the health-care industry, play a vital role in the delivery of care. Nurses work with different populations in varied settings to coordinate care aimed at the prevention of disease, promotion of health and care of sick and dying. With the impending rise in demand for quality care, skilled and specialised role of nurses is paramount to ensure high quality. The creation of advanced nursing roles and specialisation in nursing made the nurses independent and more autonomous in their roles. Advanced roles contributed a service model and best fit to the ever-changing demands of patients. At present, nurses participate in clinical research, decision-making and demonstrate clinical leadership skills to improve the safety and quality of care. Dynamic changes in the health-care industry and consumer awareness are other driving forces that influence the need for nurses to be highly competent and skilled to fulfil their responsibilities. This article briefly describes the nursing transformation in the United States and the different nursing programmes offered in India.
Using Interim Positron Emission Tomography as a Predictor for Relapse-Free Survival in Hodgkin Lymphoma
Authors: Liu Hung-Lin , Wang Ming-Chung , Kuo Chin-Yuan , Ma Ming-Chun , Liao Chun-Kai
Published: December 2021

Background:

Since the emergence of 18F-fluoro-2-deoxyglucose positron emission tomography (PET), PET has been widely implemented for the initial staging and evaluation of treatment response of classical Hodgkin lymphoma (cHL). Interim PET after two cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) has been proven to be a reliable tool to predict clinical outcomes in patients with cHL, and response-adapted therapies based on interim PET results have become the standard method of treatment. The aim of this study was to report our experience of using interim PET in our institution and determine whether it is a predictive marker for cHL. In addition, we also analyze associations between other patient characteristics and interim PET results at initial diagnosis.

Materials and Methods:

This retrospective study enrolled patients verified to have newly diagnosed cHL and who received ABVD as frontline treatment between 2008 and 2019 in our hospital. Interim PET was arranged after 2-3 cycles of ABVD, and we used Deauville 5-point score to evaluate the response. Subgroup analysis was performed to assess correlations between interim PET and patient characteristics.

Results:

Sixty patients underwent interim PET examinations. The age ranged from 14 to 74 years with a medium follow-up of 18.3 months (range: 4–113 months). The patients who had negative interim PET results (n = 36, 60%) had significantly longer relapse-free survival than those with positive results (P < 0.001). Patients with bulky disease, B-symptoms, or neutrophil to lymphocyte ratio (NLR) >6 were more likely to have positive interim PET-computed tomography results (P < 0.001, 0.023, and 0.037, respectively).

Conclusion:

Interim PET plays an important role in predicting relapse free survival for patients with Hodgkin lymphoma at our institution. A high NLR was correlated with interim PET results in this study.
Light Chain Myeloma Presenting as Chronic Diarrhea
Authors: Abdulla Mansoor C.
Published: December 2021

Light chain myeloma represents one-fifth of all cases of myeloma and light chain amyloidosis is associated with 10% of cases of myeloma. Multiple myeloma is a plasma cell disorder with diverse presentations. Here, we present a 72-year-old male with light chain myeloma with colorectal amyloidosis. Chronic diarrhea secondary to isolated colorectal amyloidosis as an initial presentation of multiple myeloma is extremely rare. Early diagnosis is important for timely therapeutic interventions which can improve the treatment outcome in this otherwise uniformly fatal disease.
Aldosterone-producing Adrenocortical carcinoma with unusual initial presentations
Authors: Chen Jen-Chieh , Wei Tzu-Chun , Pan Chin-Chen , Chang Yen-Hwa , Huang William J.
Published: December 2021

Aldosterone-producing adrenocortical carcinoma (APAC) is extremely rare. It is not only the rarest functional adrenocortical carcinoma (ACC) but also the most infrequent cause of primary hyperaldosteronism (PH). Furthermore, if hypertension and hypokalemia present in a patient with ACC, they are more likely secondary to overproduction of glucocorticoid, rather than PH. To our knowledge, APAC has not yet been reported in Taiwan with detailed clinical manifestations. We present a patient diagnosed with APAC due to an unusual initial presentation, predominantly right-sided varicocele, treated successfully by en bloc resection, being disease-free for 10 months. Due to the rarity and unfavorable outcomes of APAC, we report the patient's clinical course, treatment, and follow-up outcomes.
Infliximab (an antitumor necrosis factor) induced lupus in a patient with inflammatory bowel disease
Authors: Alsubiaee Khaled M. , Alharbi Nawal T. , Almutairi Nawaf H.
Published: December 2021

Infliximab is a monoclonal antibody that works by inhibiting the proinflammatory cytokine and tumor necrosis factor-alpha. Systemic lupus erythematosus is an autoimmune disease that affects multiple organs, and its pathogenesis involves abnormal immune complexes, environment factors, and genetics. Several reports have documented a controversy regarding infliximab-induced lupus disease. This paper reports on infliximab-induced lupus in an 18-year-old Saudi female having short stature, hypogonadism, and Crohn's disease with ileocolonic fistula. The patient developed reactive arthritis, and serology showed positive anti-double strand DNA and antihistone antibodies after infliximab administration, suggesting drug-induced lupus. More cohort studies are recommended to monitor the presentation and reversibility of infliximab-induced lupus disease.
Barriers to physical activity during pregnancy among Saudi population on the Western region
Authors: Al-Ziyadi Shatha Hallal , Almashyakhi Safa Khalaf , AlEssa Huda Abdullah , Turkistani Ola Abdullah , Al-Harthi Rahaf Sifran
Published: December 2021

Background:

Physical inactivity and sedentary lifestyles among pregnant women have shown significant health risks that threaten the life of the mother and the child.

Aim:

This study aimed to assess the prevalence and barriers to regular physical activity (PA) during pregnancy among Saudi women in the western region.

Materials and Methods:

A cross-sectional study was done with 463 pregnant women using the Pregnant Physical Activity Questionnaire. A standardized questionnaire was used to collect the demographic details and information about the PA before and during pregnancy, work-related barriers, pregnancy-related barriers, and other barriers.

Results:

Only 22.9% of the participants engaged in PA during pregnancy, and not having enough time and intense exhaustion from work were the most common work-related reasons for not exercising during pregnancy. The most reported barriers to PA related to pregnancy were fear of injuring the fetus, feeling sick in the morning, muscle and joint pain, feeling exhausted after exercise, and lack of motivation. Younger pregnant women (<20 years of age) and those who participated in a certain form of PA before pregnancy were comparatively more engaged in PA during pregnancy (P < 0.05).

Conclusion:

The PA during pregnancy, as reported by the participants, was poor and the most commonly reported barrier to do PA among pregnant women was fear of injuring the fetus. Pregnant women should receive appropriate prenatal advice on the benefits of PA, and they should be made aware of the significance of PA in the promotion of healthy lifestyle practices.
Cauchy’s surface area formula in the Heisenberg groups
Authors: Huang Yen-Chang
Published: December 2021

We show an analogue of Cauchy's surface area formula for the Heisenberg groups

\mathbb{H}_n

for

n\geq 1

, which states that the p-area of any compact hypersurface

\Sigma

in

\mathbb{H}_n

with its p-normal vector defined almost everywhere on

\Sigma

is the average of its projected p-areas onto the orthogonal complements of all p-normal vectors of the Pansu spheres (up to a constant). The formula provides a geometric interpretation of the p-areas defined by Cheng–Hwang–Malchiodi–Yang in

\mathbb{H}_1

and Cheng–Hwang– Yang in

\mathbb{H}_n

for

n\geq 2

. We also characterize the projected areas for rotationally symmetric domains in

\mathbb{H}_n

; namely, for any rotationally symmetric domain with boundary in

\mathbb{H}_n

, its projected p-area onto the orthogonal complement of any normal vector of the Pansu spheres is a constant, independent of the choice of the projected directions.
Liberation and exile: The fate of civilians during the Russo-Turkish War of 1877–1878 in Bulgarian and Turkish historiography
Authors: Popek Krzysztof
Published: December 2021

The Russo-Turkish War of 1877–1878 is traditionally called as the “Liberation War” by the Bulgarians. The conflict led to gaining freedom from the “Turkish Yoke” and started creation process of the modern Bulgarian state. The Turkish perspective on these events is significantly different. The War of 1877–1878 is remembered through the lens of the tragic experience of refugees (muhajirs) and the suffering of the Muslim civilians linked to the pogroms, emigration and exile. The paper will focus on the depiction of the fate of civilians during the conflict in contemporary Bulgarian and Turkish historiography, in which the topic is marked not only by the reliability of historical research, but also by the presence of stereotypes (as is the whole history of the 19th-century Christian-Muslim relations in Bulgaria).
Hayvan Çiftliklerinde Çalışan Sığınmacılar: Ankara Polatlı Örneği
Authors: MİLLET Sümeyye
Published: December 2021

Sığınmacı veya göçmen gruplar üzerinde yapılan araştırmalar yalnızca kimlik ve ait hissetme gibi tek boyut üzerinden değil manevi kültürün ögeleri de değerlendirildiğinde daha anlaşılabilirdir. Bu çalışmada, göç literatüründe ve ilgili yazında oldukça bahsedilen fakat hiç çalışılmamış bir alan olarak Ankara’daki hayvan çiftliklerinde hayvan bakıcısı olarak çalışan sığınmacıların sosyal ve kültürel uyumları, maddi ve manevi kültür ögeleri ile birlikte ele alınmıştır. Öncelikle mevcut alan ortaya çıkarılmış ve sonrasında bu alan üzerinde görülen sosyal ve kültürel olanlar kodlar aracılığı ve sosyolojik perspektif ile anlaşılmaya çalışılmıştır. Sonuçlar, sosyal uyum anlamında karşılaşmanın henüz gerçekleşmediğini fakat sığınmacılar için karşılaşmanın arzu edilen bir şey olduğunu, marjinalleşmenin veya ayrışmanın olmadığını ortaya koymuştur. Kültürel uyum için ise karşılaşma henüz gerçekleşmediğinden keskinleşen ve radikalleşen kimliklerin olmayışı etno-merkeziyetçiliği ölçmek yerine araştırmanın seyrini betimsel olanı algılamaya itmiştir. Bulgular hem sınıfsal anlamda, hem göç anlamında, hem de kırsal alanda bulunma anlamında ve bunlara ek olarak yaşam koşullarının zorluğu bağlamında değerlendirilmiştir. Hayvan bakıcılarını dezavantajın dezavantajlılığını yaşadıkları alt kültür grupları olarak değerlendirmeye yol açmıştır. Mekan ilişkileri ve mekanın toplumsal yaşamı yeniden inşa sürecini yarattığı düşünülerek bu alanların kontrol altında tutulmasının gerekliliği de ortaya çıkarılmıştır.
Implementing Geriatric Frailty Screening in Acute Care
Authors:   , Longley Christine
Published: December 2021

Practice Problem: Frailty is a syndrome of age-related physiologic decline characterized by an increased burden of symptoms and higher susceptibility to adverse health, including higher functional decline rates, pressure ulcers, falls, and delirium. In the general medicine unit of this project, geriatric patients were not screened for frailty. PICOT: The PICOT question that guided this project was: In hospitalized patients 65-years-of-age and older (P), how does implementing a geriatric frailty screening tool (I), compared to standard assessments (C), influence frailty identification and personalized plans of care (O) over eight weeks (T)? Evidence: Literature supports screening for frailty in the hospitalized geriatric population. Intervention: For eight weeks, a group of four RN clinicians piloted the CFS and collected data on patient appropriateness for screening, completion of screening, CFS scores, and influence of CFS scoring on personalized patient care plans. Outcome: Statistical analysis results suggest that completing the CFS and adjusting the individualized plan of care were related to one another. Conclusion: Applying best practices to identify frailty during hospitalization demonstrated a measurable influence on health promotion in acutely ill geriatric patients.
Clasificación del llanto en neonatos utilizando una red neuronal artificial con parámetros acústicos cuantitativos
Authors: Benitez Labori Guillermo Javier , Escobedo Beceiro Daniel Isac
Published: December 2021

La Neonatología define un neonato al recién nacido (RN) desde el momento del nacimiento hasta completar veinte y ocho días después del parto. Esta contribución centra su atención en el campo de las Redes Neuronales Artificiales (RNA), y específicamente supervisadas. Busca que, a través de estas redes, se pueda discriminar entre un RN sano y uno patológico a partir de su llanto en el período neonatal, siendo su objetivo implementar una RNA supervisada Back-Propagation (BP) para clasificar el llanto en neonatos con Hipoxia a partir de parámetros acústicos. Para su elaboración se concibió una metodología basada en los métodos teóricos que integró, entre otros, el método análisis-síntesis para analizar disímiles propiedades que engloban la dinámica de las RNA. Como resultado se obtuvo el clasificador de llanto (normal-patológico) implementado con RNA. Con este resultado obtenido se comprueba las potencialidades de las RNA y su uso práctico en diferentes áreas del conocimiento.
Improved Security Bound of (E/D)WCDM
Authors: Datta Nilanjan , Dutta Avijit , Dutta Kushankur
Published: December 2021

In CRYPTO’16, Cogliati and Seurin proposed a block cipher based nonce based MAC, called Encrypted Wegman-Carter with Davies-Meyer (EWCDM), that gives 2n/3 bit MAC security in the nonce respecting setting and n/2 bit security in the nonce misuse setting, where n is the block size of the underlying block cipher. However, this construction requires two independent block cipher keys. In CRYPTO’18, Datta et al. came up with a single-keyed block cipher based nonce based MAC, called Decrypted Wegman-Carter with Davies-Meyer (DWCDM), that also provides 2n/3 bit MAC security in the nonce respecting setting and n/2 bit security in the nonce misuse setting. However, the drawback of DWCDM is that it takes only 2n/3 bit nonce. In fact, authors have shown that DWCDM cannot achieve beyond the birthday bound security with n bit nonces. In this paper, we prove that DWCDM with 3n/4 bit nonces provides MAC security up to O(23n/4) MAC queries against all nonce respecting adversaries. We also improve the MAC bound of EWCDM from 2n/3 bit to 3n/4 bit. The backbone of these two results is a refined treatment of extended mirror theory that systematically estimates the number of solutions to a system of bivariate affine equations and non-equations, which we apply on the security proofs of the constructions to achieve 3n/4 bit security.
Relação da qualidade de vida, índice de massa corporal e força muscular em idosos
Authors: Souza Adriano Almeida , Caires Sabrina da Silva , Munaro Hector Luiz Rodrigues , Almeida Cláudio Bispo de , Casotti Cezar Augusto
Published: December 2021

Durante o processo de envelhecimento humano acontecem mudanças que podem interferir na qualidade de vida das pessoas. Algumas destas alterações podem ser identificadas pelo índice de massa corporal e pela força de preensão manual, e podem estar relacionadas à qualidade de vida. Neste sentido, objetivou-se discriminar, através de curvas de sensibilidade e especificidade, os pontos de corte do índice de massa corporal e da força de preensão manual como preditores de qualidade de vida em idosos residentes na zona urbana de um município de pequeno porte. Estudo epidemiológico e transversal, aprovado pelo Comitê de Ética em Pesquisa da Universidade Estadual do Sudoeste da Bahia. Os dados foram analisados por receiver-operating characteristic curves no Statistical Package for Social Sciences, e pontos de corte discriminados pelo método de Youden. Os dados sobre qualidade de vida foram coletados por meio de questionário, o índice de massa corporal por medidas antropométricas, e a força de preensão manual foi avaliada por um dinamômetro. Identificou-se 264 idosos, estes com médias de idade e de força de preensão manual de 71,85 anos (DP±7.73) e 9,99 kgf (DP±13,01), respectivamente. Os pontos de cortes preditores do desfecho, para homens e mulheres, foram <22,8 kg/m² (IC: 95%= 0,37- 0,72) para o índice de massa corporal, e <13 kgf 0,379 (IC: 95%=0,32- 0,43) para força de preensão manual. Conclui-se que os pontos de corte possuem boa capacidade para predizer elevada qualidade de vida para os idosos avaliados, entre os quais o índice de massa corporal teve maior capacidade preditiva.
Mapa digital de jogos tradicionais no Rio Grande do Sul:um olhar interativo e pedagógico
Authors: Barasuol Eduardo , Marin Elizara Carolina
Published: December 2021

O Rio Grande do Sul (RS) compõe-se por diferentes grupos sociais e modos de vida que, no processo histórico, desenvolveram, criaram e recriaram diversas manifestações culturais, dentre elas, os jogos tradicionais (JTs). Como parte do patrimônio de um povo, os jogos tradicionais merecem ser tematizados, apropriados, divulgados e nutridos por todos os indivíduos. A partir desses pressupostos, esta pesquisa objetivou (1) realizar um levantamento de jogos tradicionais no Rio Grande do Sul e (2) construir um mapa digital interativo e pedagógico que possibilite visibilizá-los por meio das Tecnologias de Informação e Comunicação (TICs). A partir do levantamento bibliográfico nas bases de indexação Lilacs, Periódicos da Capes e Google Busca, identificamos a existência de inúmeros jogos tradicionais desenvolvidos nas diversas regiões do RS, bem como estudos significativos sobre a temática, derivados especialmente de grupos de pesquisas das universidades públicas, e produções e registros de eventos, em geral de centros culturais. A consecução do mapa digital interativo e pedagógico evidencia a diversidade lúdica e cultural dos JTs. Ademais, permite aos usuários visualizarem os locais do RS onde os jogos são preponderantemente vivenciados, os modos de praticar e as fontes bibliográficas que embasaram as informações de cada jogo. O mapa digital de jogos tradicionais de caráter interativo e pedagógico apresenta-se como uma ferramenta digital à Educação Física e áreas afins, como fonte para o ensino e a pesquisa, com acesso livre e gratuito. Possibilita, ainda, que professores, alunos e usuários sejam partícipes do processo de construção e qualificação, agregando jogos e informações.