bluuebunny/crossref_metadata_2025 huggingface dataset:
NILAI KEPEMIMPINAN DALAM SALAT BERJAMAAH (TinjauanPendidikan Islam)
Authors: Imran Ali , HM M. Amir
Published: August 2022

This paper discusses the values of leadership in congregational prayers according to a review of Islamic education. Aims to reveal the meaning of congregational prayer and describe the values of leadership in the implementation of congregational prayer from the perspective of Islamic education. This research is included in the type of library research. The data collection method is carried out by conducting searches through relevant journal articles and books. The results of the study indicate that congregational prayer is a prayer that is performed in a congregational manner, which is jointly led by a faith. In congregational prayers there are two shields that the leader in front is called the imam, while the second shield is those who follow him called the makmum. Of course, what is being done is a worship activity that is carried out in two parts, namely faith and belief and both doing what is called congregational prayer.Among the leadership values that are reflected in congregational prayers include: The leader is always in front, the leader has a qualified capacity, and also motivates his congregation to always do good and spread many benefits to others.
Aligning the Outputs of the Department of PE and Sports Science with the Needs of Omani Labor Market for Specialists in Sports Management in Light of Oman Vision 2040
Authors: Al Qaidi Abdullah , Al Busafi Majid , Al-Kalbani Qusai , Al Maamari Al Mutaz , Al Jahwari Tariq , Al Hadabi Hilal , Ambo-Ali Nusaiba , Al-Habsi Khalsa , Al-Harrasi Arwa
Published: August 2022

This study aims to align the outputs of the Department of Physical Education (PE) and Sports Science with the needs of the Omani labor market for specialists in sports management in light of Oman vision 2040 (in the areas of education and economics), by identifying the extent to which the labor market needs to create programs specialized in sports management in the Department of Physical Education and Sports Sciences. The study used the descriptive approach using a questionnaire. The size of the research sample was 211 respondents from institutions related to the field of physical education and sports science, and who are benefiting from the outcomes of sports management. The results of the study indicated that: there is an urgent need to introduce the Sports Management major to be offered in the Department of Physical Education and Sports Science; administrative tasks in sports institutions reflect the need to have specialists in sports management. The research team recommended that the Department of PE and Sports Science should be informed on the experiences of similar departments at other higher education institutions that have introduced such programs. Furthermore, the study recommended the formation of a joint committee between the Department and the concerned institutions to discuss the needs of the labor market, to review the Department's policies towards introducing the specialty of sports management, and to consider the possibility of adapting the study plan for partnership with colleges related to sports management to offer majors serving students specializing in sports management.
ВІДОБРАЖЕННЯ ЗБРОЙНИХ СИЛ УКРАЇНИ ТА ПРИКОРДОННИХ ПРАВООХОРОННИХ ОРГАНІВ СПЕЦІАЛЬНОГО ПРИЗНАЧЕННЯ В СУЧАСНІЙ НУМІЗМАТИЦІ
Authors: Кривцов Артем , Кривцов Олег , Царенко Олена
Published: August 2022

Дана робота присвячена пам’ятним монетам Національного банку України із серій «Збройні Сили України» і «Пам'ятки архітектури України»: «Державна прикордонна служба України», «Десантно-штурмові війська Збройних Сил України», «Збройні Сили України», «Сухопутні війська Збройних Сил України» та «Гарнізонний храм святих апостолів Петра і Павла (м. Львів)». Досліджено геральдичні знаки, які відображені на монетах та історичні етапи становлення Державної прикордонної служби України та окремих родів військ і сил Збройних Сил України.
ВРАЖАЮЧІ ФАКТОРИ РАДІОАКТИВНОГО І ХІМІЧНОГО ЗАБРУДНЕННЯ АТМОСФЕРИ. АНАЛІЗ ІСНУЮЧИХ МЕТОДІВ ЗАХИСТУ НАСЕЛЕННЯ
Authors: Фаррахов Олександр , Лисиченко Олександра
Published: August 2022

В статті розглядаються вражаючі фактори радіоактивного забруднення атмосфери і обставини, що викликають їх появу, проаналізовано вражаючі фактори хімічного забруднення атмосфери і причини їх виникнення, а також систематизовано відомості про існуючі методи та способи захисту військ і населення від вражаючих факторів радіоактивного та хімічного забруднення атмосфери і оцінено ефективність їх застосування.
АКТУАЛІЗАЦІЯ ЕКЗИСТЕНЦІАЛЬНОГО АСПЕКТУ ПРОФЕСІЙНОЇ ІДЕНТИЧНОСТІ ЯК ЧИННИК ВИХОВАННЯ ОСОБИСТОСТІ МАЙБУТНІХ ЛІКАРІВ В УМОВАХ ВОЄННОГО СТАНУ В УКРАЇНІ
Authors: Касьянова Олена , Разумна Алла
Published: August 2022

Визначено психологічну особливість професійної ідентичності майбутнього лікаря в умовах воєнного стану, обґрунтовується здійснення особистісних виборів соціально-екзистенціального, професійно-екзистенціального та екзистенціально-вітального в професійній самоідентифікації в умовах воєнного стану. Окреслені суб’єктивні умови особистісно зрілого вибору: суб’єктність, усвідомленість, осмисленість, рефлективність. Диференціюється чотири можливих варіанти відповідних особистісних виборів: соціально-професійно-вітально ризикований, соціально-професійно ризикований і вітально безпечний і соціально і вітально безпечний позапрофесійний вибір. Окреслено важливі умови здійснення виховання особистості фахівця в умовах воєнного стану: забезпечення прийняття усвідомленого, осмисленого, суб’єктного, рефлексивного рішення щодо професійної самоідентифікації з його безпосереднім втіленням у особистісно-професійне буття майбутнього лікаря. Важливими умовами здійснення виховання особистості фахівця в умовах воєнного стану, що здатен до виконання професійних функцій в ризикованих умовах цього стану, є забезпечення прийняття усвідомленого, осмисленого, суб’єктного, рефлексивного рішення щодо професійної самоідентифікації з її безпосереднім втіленням у особистісно-професійне буття майбутнього лікаря.
КОНКУРЕНТОСПРОМОЖНІСТЬ ОСОБИСТОСТІ VS КОНКУРЕНТОСПРОМОЖНІСТЬ ФАХІВЦЯ
Authors: Орап Марина , Вовк Валентина
Published: August 2022

Стаття присвячена викладу результатів теоретичного осмислення змістового наповнення дефініцій «конкурентоспроможність особистості» та «конкурентоспроможність фахівця» у філософських, економічних та психологічних дослідженнях. З’ясовано, що передумовами соціально-психологічного вивчення конкурентоспроможності індивіда стали дослідження у соціально-економічній парадигмі в аспекті конкурентоздатності підприємств, продукції, вивченні конкурентних переваг. У такому ракурсі поняття «конкуренція» перебуває в одному семантичному полі з поняттями «змагання», «боротьба», «переваги». Відтак, психологічні дослідження конкурентної позиції фахівця виокремлювали ті характеристики, які забезпечують спеціалісту конкурентні переваги на ринку праці. Дослідження новітньої галузі науки – поведінкової економіки – змінили акценти у вивченні даного питання. Якщо конкурентність у класичній економіці розглядалась як цінність товару чи послуги на ринку, то конкурентність фахівця акцентує його цінність як професіонала. Таким чином спостерігається зміщення парадигми вивчення конкурентоспроможності – із акцентування змагальності та протиставлення концепту «партнерство», на формування, вияв і презентацію власних конкурентних переваг як висококваліфікованого і компетентного спеціаліста. Відтак, сучасні психологічні дослідження розглядають конкурентоздатність людини як результат оволодіння нею певними необхідними компетентностями та здатністю до презентації цих компетентностей на ринку праці. Логіка психологічних досліджень призвела до вивчення конкурентоспроможності як характеристики особистості, яка розглядається ,у найбільш загальному вигляді як системна характеристика, яка забезпечує швидку адаптацію до навколишнього середовища, здатність генерувати нові, оригінальні ідеї, аргументувати їх важливість для соціального, професійного та особистого розвитку і створювати умови для ефективного втілення цих ідей, формує потребу особистості в досягненні успіху, розкриття особистісного потенціалу. Здійснений теоретичний аналіз дав змогу зробити висновки про те, що поняття «конкурентоспроможність фахівця» з необхідністю враховує характеристики його як особистості у поєднанні їх професійними компетенціями, що має влив на успішність виконання професійних завдань та акцентує увагу на унікальності власних професійних компетенцій в обраній діяльності. У сучасних суспільних реаліях конкурентоспроможний фахівець – це особистість, котра має, чітко усвідомлює та вміє презентувати свої конкурентні переваги (як особистісні, так і професійні) на ринку праці, у повсякденному та професійному житті.
МОЖЛИВОСТІ «WORKSHOP», ЯК МЕТОДУ УДОСКОНАЛЕННЯ ВМІНЬ І НАВИЧОК З ДИТЯЧОЇ ТЕРАПЕВТИЧНОЇ СТОМАТОЛОГІЇ
Authors: Савичук Олександр , Зайцева Євгенія , Шаповалова Ганна
Published: August 2022

Викладання дисципліни «Дитяча терапевтична стоматологія» потребує комплексного підходу з застосуванням сучасних методів засвоєння матеріалу [1-4]. “Workshop” є одним з таких сучасних методів навчання [5]. Опановуючи методи пломбування каріозних порожнин (КП) при роботі з дітьми ми прагнемо розкрити можливості існуючих методів пломбування каріозних порожнин з використанням різних матеріалів, як одного з найважливіших етапів оперативного лікування карієсу [6-7]. Метою “Workshop” є удосконалити навички студента володіння різними техніками пломбування каріозних порожнин та уміння обирати найбільш адекватну з них на практиці з урахуванням топографії каріозної порожнини (І-V кл за Блеком) та в залежності від анатомічної групи зубів, використовуючи весь арсенал стоматологічних інструментів [8-10].
الحماية الجنائية للنتاج الذهني التقني - الاختراع انموذجا
Authors: الشكري عادل يوسف , آلبو صيبع زينب محمد
Published: August 2022

إن توفير الحماية لهذا النوع من الحقوق يعود إلى فكرة حماية شخصية صاحب النتاج الذهني والخلق الفكري من الاعتداء عليها, ولذلك عنيت جل التشريعات بتنظيمها وتوفير الحماية لها, ولم يقتصر ذلك على النطاق الوطني فحسب بل تعداه إلى تنظيم اتفاقيات دولية متخصصه في هذا الشأن.وتبرز اهمية توفير الحماية للنتاج الذهني بأنه سينعكس على حماية الانتاج الصناعي, لأن النهضة الصناعية التي شهدتها الدول، كانت وليدة الآلة التي هي نتاج الذهن والفكر الانساني, فضلاً عن ذلك فأن حماية الابداع الذهني يؤدي الى توفير بيئة آمنه، ما يشجع ذلك على ولادة صناعات جديدة لم تكن معروفة سابقاً.وانطلاقاً مما تقدم تتبلور مشكلتنا البحثية وذلك في الاجابة على السؤال المحوري التالي: هل وفرَّ المشرع العراقي حماية جنائية للنتاج الذهني المتمثل بالاختراع؟ وإذا كان كذلك ما مدى نجاعة التنظيم التشريعي العراقي في توفير حماية فعّالة له؟.ولغرض الوصول الى الغاية المبتغاة من الدراسة فأننا سنتخذ من المنهج الاستقرائي التحليلي منحى لدراستنا، وفي ضوء ما اتخذناه من منهج سنقسم هذه الدراسة الى مبحثين: تسبقهما مقدمة، وتعقبهما خاتمة, وسنعقد المبحث الأول، للتعريف بالاختراع قانوناً، ونخصص المبحث الثاني، لدراسة التنظيم التشريعي لحماية الاختراع جنائياً.
ميناء مبارك بين القواعد القانونية الدولية والوطنية
Authors: الشكراوي علي هادي , مهنا باسل محسن
Published: August 2022

لا يوجدhttps://dx.doi.org/10.36322/jksc/0105201CrossRef submission ID: 1460301916
الاتساق المعجمي في سورة البلد
Authors: العلاق جليلة صالح
Published: August 2022

لا يوجدhttps://dx.doi.org/10.36322/jksc/0105207CrossRef submission ID: 1461062485
الجهود اللغوية للشيخ الشبيبي في المجامع العلمية
Authors: العبيدي اسيل سامي
Published: August 2022

لا يوجدhttps://dx.doi.org/10.36322/jksc/0105205CrossRef submission ID: 1460844456
Precautionary measures for infectious diseases in the light of Islamic Shariah (An Analytical study)
Authors: Aziz Dr. Asma , U dduja Kashaf , Naz Shama
Published: August 2022

Islam is not only a religion of religious adulation but also provides a complete and sufficient knowledge on all stages of human life. It has provided us complete knowledge on maintenance of human’s health and purifications. Furthermore, it has guided us to abstain from all the harmful things which causes damage to human’s life. Among all the sicknesses, infectious diseases cause the most hazardous effect on mankind all around the world. In recent COVID-19 pandemic situation, World Health Organization (WHO) has specified the precautionary measures to ensure the safety of human health.  According to the guidelines instructed by World Health Organization, Government and health specialists around the world take some initiatives to control the extent of infectious virus. It is considered to be the most contagious when people are most symptomatic. In general, there are few or no treatment options for viral diseases. There are some precautions to be taken to overcome the pandemic. These steps include; frequently cleaning of hands with soap or alcohol based sanitizer, covering nose and mouth when coughing or sneezing, keeping distance from persons with cold and flu. Islam is a complete code of life for mankind. It strongly emphasis on the precautions and cleanliness. Hence in present-day condition the guidelines provided by health organizations are already mentioned in Islamic Shariah and was followed by ?a??bahs and Islamic authorities. No doubt we must consider Islamic teachings for the betterment of society. Firstly, as a Muslim it is important to seek Allah’s protection and being a responsible citizen, it is obligatory to act upon the precautions specified by the health specialists and strictly follow the rules indicated by Government. In this article, the traditions and teachings of Holy Prophet SAW regarding the health, cleanliness and religious rituals  are discussed along with the safety measurements provided by WHO which includes cleanliness, better healthy food, quarantine, and social distancing etc. will be discussed thoroughly.
COMPARISON OF TEACHING TURKISH AS A FOREIGN LANGUAGE IN EUROPE AND TURKEY
Authors: KURT Özlem , AYTAŞ Gıyasttin
Published: August 2022

Knowing and getting to know a language has usually maintained its importance as a primarynecessity during history. It is considered thatlearning Turkish as a foreign language appears as a result of an obligationora necessity. Teaching TFL, which commenced in Venice with the purpose of educating translators who can speak Turkish, in the course ofthe developing process is accomplished in a more systematic and academic structure. Besides the teachings executed outside of Turkey, the number of academic institutions related to teaching Turkish as a foreign language has additionally improved in Turkey. To expose how these teaching processes are carried out, it becomes evaluated how the teaching process of Turkish as a foreign language was accomplished in Europe and Turkey, based on the sample of the Turkish Departmentat Ghent University and Gazi University Tömer. The datas obtained by the document review method were subjected to content analysis. Relating to the teaching-learning content the textbook which is used in the Turkish department at Gent University is more focused on the audio-linguistic method andGazi University Tömer’s textbook is more focused on the communicative method. As a result of the evaluations, it isnoticed that text selection and use these resources are based on special requirements and needs. Key Words: Ghent University, Gazi University, Teaching Turkish as a foreign language.
IN-VITRO EFFECTS OF HESPERIDIN ON HUMAN ERYTHROCYTES SICKLING WITH MODIFICATIONS OF FUNCTIONAL CHEMISTRY
Authors: Nwankwo H. C. , Uraku A. J. , Uraku O. H. , Koroma B. M.
Published: August 2022

Sickle cell disease (SCD) is still one of the highest leading inbred hemoglobinopathy amid Africans. The In-vitro effects of hesperidin on sickling human erythrocytes with functional chemistry of human sickle erythrocytes were investigated by standard methods.The induction of sickle cell in erythrocytes was done using 2%sodium metabisulphite at 3 hours optimally. The prevention and curative approaches (PA and CA) were adopted in comparison of human erythrocytesfrom AA-genotype. The erythrocytes were grouped into 3; AA–hesperidin treated (AA××), AA–hesperidin treated (AA×) and sickle cell serving as negative control (NC). The results showed 83% and 86% antisickling potency of hesperidin for prevention and curative approaches respectively. The results of functional chemistry analysis showed that hesperidin modifies the functional groups in favor of its antisickling effects judging from the FTIR observed bends and shifts. From GC-MS and LC-MS analyses, it was practical that hesperidin treatment favors the productions of fatty acid alkyl monoesters (FAMEs) with concomitant shutting down-effects on selenocompound metabolism. Pathway enrichment and topology analyses revealed non-specifically activation of fatty acid biosynthesis, linoleic acid metabolism and steroid hormone biosynthesis pathways upon hesperidin treatment. Thus, sickling-suppressive effects of hesperidin could potentially be associated with modulation of oxygenated and deoxygenated haemglobinthroughpossible modification of human sickle erythrocyte’s functional chemistry.
2SLGBTQIA+- Sexuality in Changing Canadian Lutheran Contexts and Identities
Authors: Kuhnert Karen
Published: August 2022

With attention to diverse history, theology, experiences and concerns, this article uses Lutheran contexts and identities to construct a frame for the eventual telling of untold 2SLGBTQIA+ stories. This paper provides accessible structural elements (narratives, time-markers, web-links, videos and image files from reputable sources in Canadian and Lutheran history and theology so readers interested in life-giving quests of belonging can more easily and accurately engage in the ongoing work of reformation from the position of unity in the Gospel that sets people free.
Fraturas e Luxações
Authors: Giordano Vincenzo , Giordano Carolina , Serrão de Souza Felipe , Giordano Marcos , Esteves Pires Robinson
Published: August 2022

Fraturas e luxações são urgências músculo-esqueléticas traumáticas que afetam o bem-estar do indivíduo que as sofre. Apresentam sintomas comuns, que compreendem dor de moderada e grande intensidade, deformidade e aumento de volume no local da lesão, muitas vezes com redução ou perda completa da função do segmento. Neste artigo, os autores abordam estas lesões, descrevendo métodos diagnósticos e tratamento.
Impact of IL-10-1082A\G promoter gene polymorphism and production in lung cancer patients
Authors: Nomi Aqeel Wadi , Darweesh Mayyada F.
Published: August 2022

Lung cancer a deadliest  malignant disease , Cytokines play a critical role in regulating host immune response toward cancer and determining the overall fate of tumorigenesis. So this study aimed to investigate the impact gene variation of IL-10 promotor region on production of IL-10 cytokine and their effect on lung cancer outcome.  The aim of this study is the detection of IL-10-1082A\G polymorphism and IL-10 serum level with it correlation to progression of disease. A Case-control study was performed to 150  Lung cancer patients patients 54 females and 96 males and matched with age and gender attending to Middle Euphrates Cancer Center in AL-Najaf province with group of 60 healthy individual as control. Blood sample was collected from all patients and control. IL-10 level were measured by enzyme-linked immunosorbent assay (ELISA). Single nucleotide polymorphism detected by ARMS-PCR technique. The result shown that  IL-10-1082 G/A significantly (P<0.05) high frequencies of homozygous GG, and G allele carrier in lung cancer patients, in contrast homozygous AA  and AG genotype and A allele appear at low frequency with patients. The data showed that genetic variants of the IL-10 affect the IL-10 production and associated with the progression of disease.
Determinants of multidrug-resistant tuberculosis in patients attending tertiary care teaching hospital, Vijayapur
Authors: Hugar Leela , Chhabra Deeksha , Patil Jyoti .S.
Published: August 2022

Background: Multidrug-Resistant Tuberculosis (MDR-TB) has a more rapid course with poor treatment outcomes. Its treatment requires complex multiple 2nd line drug regimens which are longer, more expensive and more toxic Objectives: to identify factors associated with multidrug-resistant tuberculosis in order to identify high risk population who would develop MDR-TB and to suggest possible measures to be taken to reduce MDR-TB incidences in this region. Methods: A structured questionnaire in the vernacular language was used to collect information from study participants and was interviewed privately, and their names were not written on the questionnaire to ensure confidentiality. . Quantitative data were expressed as mean and standard deviation; the qualitative data were expressed as percentages and proportions Results: correlation of HIV positivity was observed in 9(15.3 %) patients. 14(23.7%) patients lived with TB patients earlier. Other diseases (including HIV) were present in 20(33.9%) patients. Excluding HIV, 6 had Diabetes Mellitus, 4 were chronic alcoholics and 1 had psychiatric illness. 12(20.3%) had a history of smoking. The previous TB treatment history of patients undergoing retreatment included site of TB infection being pulmonary in 41(69.5%) and only 2(3.4%) had extrapulmonary TB.27 (62.8%) patients were smear positive during first anti –TB treatment.
Relationship of Body Image Concerns with some Gynecological Diseases and Chronic Fatigue Syndrome: A Review
Authors: Ojha Ankita , Kumar Dhananjay
Published: August 2022

The present paper was intended to examine the relationship among gynaecological diseases (Polycystic Ovarian Syndrome (PCOS), Endometriosis), Chronic Fatigue Syndrome, and Fibromyalgia with body dissatisfaction. A review of papers published between 2003 and 2021 as found by Google Scholar, PubMed, academia, and publish or perish.The review included studies conducted on women’s samples of reproductive age group at various developmental stages.Results indicated a relationship between body dissatisfaction and chronic fatigue syndrome. Women with PCOS reported greater body dissatisfaction, higher body uneasiness, and body image distress. Endometriosis is related to body image. Endometriosis and PCOS are also found to be related to chronic fatigue syndrome. Findings indicated the psychosomatic origins of these physical conditions as the source or antecedent factors for biologically vulnerable subjects and were explained in this framework. This body of knowledge will add to the area. Different psychological counsellors and therapeutic practitioners will utilise this knowledge to deal with such problems during sessions in clinical and hospital settings.
A EXPERIÊNCIA COM O CORPO MOTRIZ: criação e poética em dança contemporânea
Authors: Silva Kleber Rodrigo Lourenço
Published: August 2022

Este artigo é a reelaboração de um capítulo da minha dissertação de mestrado, intitulada Da dança armorial ao corpo motriz: em busca do corpo brincante, apresentada em 2015 na Universidade Estadual Paulista (Unesp). Busco refletir sobre uma experiência de pesquisa em dança contemporânea: a criação do espetáculo Negro de estimação (2007), compartilhando aspectos do seu processo criativo que caracterizam a investigação por uma poética em dança, bem como relatos da trajetória da obra, que esteve em cartaz por treze anos. Esses apontamentos provocam reflexões sobre escrita em dança, performance e historicidade nas artes. O espetáculo aborda as linguagens do teatro e da dança, criando uma dramaturgia singular, que expõe as tensões vividas pelo sujeito negro em sociedade e os seus descentramentos. Nesse contexto de pesquisa, articularam-se também pensamentos sobre as matrizes e motrizes culturais nas artes negras performativas, dando origem à terminologia “corpo motriz” – método de investigação corporal no espetáculo. Quer-se, aqui, gerar reflexões sobre a linguagem em dança e seus modos de produção no panorama atual da cena brasileira.
PPP2R1A neurodevelopmental disorder is associated with congenital heart defects
Authors: Baker Elizabeth K. , Solivio Beulah , Pode‐Shakked Ben , Cross Laura Ann , Sullivan Bonnie , Raas‐Rothschild Annick , Chorin Odelia , Barel Ortal , Bar‐Yosef Omer , Husami Ammar , Hopkin Robert J. , Prada Carlos E. , Stottmann Rolf W. , Weaver Kathryn Nicole
Published: August 2022

Protein phosphatase 2A (PP2A) is a heterotrimeric serine/threonine phosphatase that regulates numerous biological processes. PPP2R1A encodes the scaffolding “Aα” subunit of PP2A. To date, nearly 40 patients have been previously reported with 19 different pathogenic PPP2R1A variants, with phenotypes including intellectual disability, developmental delay, epilepsy, infant agenesis/dysgenesis of the corpus callosum, and dysmorphic features. Apart from a single case, severe congenital heart defects (CHD) have not been described. We report four new unrelated individuals with pathogenic heterozygous PPP2R1A variants and CHD and model the crystal structure of several variants to investigate mechanisms of phenotype disparity. Individuals 1 and 2 have a previously described variant (c.548G>A, p.R183Q) and similar phenotypes with severe ventriculomegaly, agenesis/dysgenesis of the corpus callosum, and severe CHD. Individual 3 also has a recurrent variant (c.544C>T, p.R182W) and presented with agenesis of corpus callosum, ventriculomegaly, mild pulmonic stenosis, and small patent foramen ovale. Individual 4 has a novel variant (c.536C>A, p.P179H), ventriculomegaly, and atrial septal defect. To conclude, we propose expansion of the phenotype of PPP2R1A neurodevelopmental disorder to include CHD. Further, the R183Q variant has now been described in three individuals, all with severe neurologic abnormalities, severe CHD, and early death suggesting that this variant may be particularly deleterious.
A novel Fe3O4@TCH@Ni(II) nanoparticle: An efficient magnetically retrievable nanocatalyst for C–C and C–heteroatom bond formation reaction
Authors: Karkon Elahe Gholamiyan , Mostafavi Hossein
Published: August 2022

Layered Ni(II) complex on magnetic nanoparticle as heterogeneous, efficient, novel, green, and reusable catalyst was used to cross‐coupling reaction, including carbon–carbon, carbon–nitrogen, and carbon–oxygen formations. The covalent functionalization of organic ligand, thiocarbohydrazide (TCH), on the surface of magnetic nanoparticle (Fe3O4) was determined that leading to an exceptional adsorptive ability for supporting Ni(II). The magnetic nano‐composite was characterized and investigated by using Fourier‐transform infrared spectroscopy (FT‐IR), thermogravimetric analysis (TGA), energy dispersive X‐ray (EDX), X‐ray diffraction (XRD), scanning electron microscope (SEM), inductively coupled plasma–optical emission spectrometry (ICP‐OES), transmission electron microscopy (TEM), and Brunauer–Emmett–Teller (BET). Also, three cross‐coupling reactions in the presence of Fe3O4@TCH@Ni(II) were optimized in terms of temperature, amount of catalyst, solvent, and time.
Pervaporative desalination of high salinity water using chitosan‐based thin film composite membranes
Authors: Li Zhelun , Baig Absar , Shahidi Kazem , Hudson Alexander , Roth Leah , Hatahet Mason , Wang Xuezhen
Published: August 2022

Pervaporation is regarded as one of the most promising technologies for desalination due to its extremely low energy consumption and ability to process high salinity solutions. As an easily accessible natural material with various advantages, chitosan is a promising material for pervaporative desalination. However, the research in this regard is scarce, and all existing works only focus on the desalination of NaCl solutions. Since chitosan has the potential to chelate with various ions, its desalination performance for different salt solutions might vary. In this study, we applied chitosan‐based membranes to pervaporative desalination for various salt solutions. The effects that feed salts, feed concentration, and temperatures had on their performance were comprehensively investigated. Moreover, two types of chitosan (Chitosan‐K and Chitosan‐D) were utilized to investigate the impact of chitosan types and confirm the universality of the conclusion. It was found that the feed salts significantly impact the desalination performance of chitosan membrane depending on their chelation level with chitosan polymers, and the cations (rather than anions) of the salts have a more significant effect. The salt rejection was almost complete at all tested conditions, demonstrating chitosan to be a promising material for pervaporative desalination.
Preparation and properties of modified graphene oxide / polyacrylamide composite nanoparticle gel system
Authors: Chen Yang , Li Xin , Zheng Shuang , Tian Yuqin , Zhu Rongjiao , Feng Xia , Liu Cunhui , Zhang Yichen
Published: August 2022

Graphene oxide (GO) itself has a high viscous force on water and is very hydrophilic. To improve its hydrophobicity, adsorption performance, surface activity and stability, GO is needed to be modified for petroleum drive regulation applications. Therefore, GO was functionally modified with octadecylamine, and their structures were characterized by FT‐IR, X‐ray photoelectron spectroscopy (XPS), TGA, and SEM. Furthermore, the effective modification of long chain alkyl amine was verified. Then, the composite nanoparticle gel system was prepared by the interaction of modified graphene oxide (X‐GO) with polyacrylamide (HPAM) via chemical or physical forces. The optimal preparation conditions were determined by the response surface method (RSM). Under the optimal preparation conditions, the blocking rate can reach 95.27%. Turbiscan Lab stability omnipotent stability analysis and viscoelasticity testing showed that the composite gel system had good stability and viscoelasticity. The particle size result showed that the composite system was a nano system. In addition, the X‐GO/HPAM composite nanoparticle gel system also showed good temperature resistance, salt resistance, and shear resistance in performance tests. Finally, the result of the core‐blocking rate and breakthrough pressure test showed that it had good blocking performance, with a blocking rate of more than 95%.
Phenotype‐informed polygenic risk scores are associated with worse outcome in individuals at risk of Alzheimer's disease
Authors: Nordengen Kaja , Pålhaugen Lene , Bettella Francesco , Bahrami Shahram , Selnes Per , Jarholm Jonas , Athanasiu Lavinia , Shadrin Alexey , Andreassen Ole A. , Fladby Tormod
Published: August 2022

Introduction

Patients with predementia Alzheimer's disease (AD) and at‐risk subjects are targets for promising disease‐modifying treatments, and improved polygenic risk scores (PRSs) could improve early‐stage case selection.

Methods

Phenotype‐informed PRSs were developed by selecting AD‐associated variants conditional on relevant inflammatory or cardiovascular traits. The primary outcome was longitudinal changes in measures of AD pathology, namely development of pathological amyloid deposition, medial temporal lobe atrophy, and cognitive decline in a prospective cohort study including 394 adults without AD dementia.

Results

High‐risk groups defined by phenotype‐informed AD PRSs had significantly steeper volume decline in medial temporal cortices, and the high‐risk group defined by the cardiovascular‐informed AD PRS had significantly increased hazard ratio of pathological amyloid deposition, compared to low‐risk groups.

Discussion

AD PRSs informed by inflammatory disorders or cardiovascular risk factors and diseases are associated with development of AD pathology markers and may improve identification of subjects at risk for progression of AD.
On‐site forensic analysis of colored seized materials: Detection of brown heroin and MDMA‐tablets by a portable NIR spectrometer
Authors: Kranenburg Ruben F. , Ramaker Henk‐Jan , van Asten Arian C.
Published: August 2022

The increasing workload for forensic laboratories and the expanding complexity of the drug market necessitates efficient approaches to detect drugs of abuse. Identification directly at the scene of crime enables investigative forces to make rapid decisions. Additionally, on‐site identification of the material also leads to considerable efficiency and cost benefits. As such, paperwork, transportation, and time‐consuming analysis in a laboratory may be avoided. Near‐infrared (NIR) spectroscopy is an analysis technique suitable for rapid drug testing using portable equipment. A possible limitation of spectroscopic analysis concerns the complexity of seized materials. NIR measurements represent composite spectra for mixtures and diagnostic spectral features can be obscured by excipients such as colorants. Herein, a NIR‐based (1300–2600 nm) detection of heroin and MDMA in colored casework (i.e., brown powders and ecstasy tablets) using a portable analyzer is presented. The application includes a multistage data analysis model based on the net analyte signal (NAS) approach. This identification model was specifically designed for mixture analysis and requires a limited set of pure reference spectra only. Consequently, model calibration efforts are reduced to a minimum. A total of 549 forensic samples was tested comprising brown heroine samples and a variety of colored tablets with different active ingredients. This investigation led to a >99% true negative and >93% true positive rate for heroin and MDMA. These results show that accurate on‐site detection in colored casework is possible using NIR spectroscopy combined with an efficient data analysis model. These findings may eventually help in the transition of routine forensic laboratories from laboratory‐based techniques to portable equipment operated on scene.
Temporal stability of the hemodynamic response function across the majority of human cerebral cortex
Authors: Taylor Amanda J. , Kim Jung Hwan , Ress David
Published: August 2022

The hemodynamic response function (HRF) measured with functional magnetic resonance imaging is generated by vascular and metabolic responses evoked by brief (<4 s) stimuli. It is known that the human HRF varies across cortex, between subjects, with stimulus paradigms, and even between different measurements in the same cortical location. However, our results demonstrate that strong HRFs are remarkably repeatable across sessions separated by time intervals up to 3 months. In this study, a multisensory stimulus was used to activate and measure the HRF across the majority of cortex (>70%, with lesser reliability observed in some areas of prefrontal cortex). HRFs were measured with high spatial resolution (2‐mm voxels) in central gray matter to minimize variations caused by partial‐volume effects. HRF amplitudes and temporal dynamics were highly repeatable across four sessions in 20 subjects. Positive and negative HRFs were consistently observed across sessions and subjects. Negative HRFs were generally weaker and, thus, more variable than positive HRFs. Statistical measurements showed that across‐session variability is highly correlated to the variability across events within a session; these measurements also indicated a normal distribution of variability across cortex. The overall repeatability of the HRFs over long time scales generally supports the long‐term use of event‐related functional magnetic resonance imaging protocols.
Using technology‐mediated inquiry to help young learners reimagine the visible world through simple particle models
Authors: Samarapungavan Ala , Bryan Lynn A. , Staudt Carolyn , Sapkota Bima , Will Pinto Hector E. , Broadhead Jamie M. , Kimball Nathan
Published: August 2022

This research explored kindergarten students' learning of simple particle models to explain the properties and behavior of matter in the solid, liquid, and gas states and during phase transitions (evaporation, melting, freezing, and condensation). Science instruction for young learners tends to focus on the concrete and directly observable. This focus on the here and now of experience can foreclose opportunities for young learners to explain their world in terms of the mechanisms posited by modern science. The current research examined how kindergarten children's models of matter develop as they engage with technology‐mediated, model‐based inquiry lessons. Data were collected from two intervention groups who engaged in a series of modeling lessons with the aid of digital tools for visualizing and explaining particle behavior across varied material phenomena. The two intervention groups engaged in a common set of modeling activities but differed in the use of one digital tool. Intervention students were interviewed in the week before the beginning of the intervention and the week following the completion of the intervention to assess the development of their models of matter. To provide a baseline for comparison, we assessed a third group of kindergarten children who did not receive any instruction on matter in the same time frame as the intervention students. Data were coded using cognitive science techniques of verbal protocol analysis. Repeated measures ANOVAs were conducted to explore changes across the pre‐ and post‐intervention interviews. We found that children from both intervention groups showed significant gains in the use of particle models to explain material phenomena, while the comparison group showed only small gains in the use of particle models.
Experimental investigation of CMT discontinuous wire arc additive manufacturing of Inconel 625
Authors: Votruba Vojtěch , Diviš Ivan , Pilsová Lucie , Zeman Pavel , Beránek Libor , Horváth Jakub , Smolík Jan
Published: August 2022

Additive manufacturing (AM) is a progressive technology which holds promise for manufacturing of heat resistant super alloys. One of the most productive methods is wire arc additive manufacturing (WAAM). In this article, an alternative WAAM strategy is investigated. Experimental clads and material tests were performed to evaluate the material properties obtained through a cold metal transfer (CMT) discontinuous WAAM of Inconel 625 alloy. Using the modern terminology of Fronius Gmbh this method is called CMT cycle step. The difference is that it is automatically controlled by the welding source. CMT discontinuous WAAM has lower productivity and a higher consumption of shielding gas. However, it excels in low heat input and precise material cladding in comparison with a standard CMT continuous WAAM. It enables fabrication of finer details even on thin-walled components or in sections with problematic heat dissipation. Samples manufactured using this strategy were also compared with samples manufactured through a standard CMT continuous WAAM. Two sets of manufactured samples were thus tested. The following material tests were performed: (i) metallographic analysis, (ii) x-ray tomography, (iii) SEM analysis, (iv) hardness, (v) tensile strength (20 °C, 650 °C) and (vi) pin-on-disc (20 °C, 650 °C). The results show that the CMT discontinuous WAAM led to improved material properties in the Inconel 625 samples. Ultimate tensile strength improved by 15% at 20 °C and by 4% at 650 °C. Wear resistance at 650 °C was about two times higher. This paper concludes that the CMT discontinuous WAAM for Inconel 625 is definitely suitable for manufacturing of complex shapes, fine details and thin-walled components.
Controls and performance: assessing the mediating role of creativity and collegiality
Authors: Su Sophia , Baird Kevin , Tung Amy
Published: August 2022

This study examines the mediating role of two types of employee related behaviour, creativity and collegiality, in the association between the use of Snell’s (1992) three control types (i.e. input, behaviour, and output) with individual employee job performance and organisational performance. An online survey questionnaire was used to collect data, with 203 responses received from Australian lower-level managers. The findings reveal that while output controls influence both individual employee job performance and organisational performance directly, creativity and collegiality play significant roles in mediating the associations between input and behaviour controls with both individual employee job performance and organisational performance. Overall, the findings contribute to the MCS literature by providing an empirical insight into how the use of different types of controls can enhance specific aspects of performance, i.e. individual employee job performance, and organisational financial and non-financial performance, via employee related behaviour (creativity and collegiality). Such findings have important implications for practice.
The description, distribution and habitat of wild banana species in northern Viet Nam
Authors: Vu Tuong Dang , Vu Dang Toan , Janssens Steven B. , De Langhe Edmond , Le Loan Thi , Kallow Simon , Mertens Arne , Vu Thi Thu Hien , Nguyen Thanh Tuan
Published: August 2022

Northern Viet Nam displays a remarkable diversity of wild bananas (Musa L.), including the species from which the majority of cultivated bananas derive. The taxonomy and exact distribution of these wild bananas are however not well known, limiting their conservation and use. In the present study, we describe the morphology, ecology, and phytogeography of the 6 Musa species that were collected between 2016 and 2019 in northern Viet Nam: Musa acuminata Colla, M. balbisiana Colla, M. itinerans Cheesman, M. haekkinenii N.S.Ly & Haev, M. lutea R.V.Valmayor, L.D.Danh and Hakkinen and M. paracoccinea A.Z.Liu and D.Z.Li:. Of these, M. itinerans was the species with the most widespread distribution range, occurring as large mats in various habitats between 136 and 1331 m, whereas M. acuminata was found between 136 and 989 m and M. balbisiana was between 108 and 981 m. Furthermore, M. lutea, M. paracoccinea and M. haekkinenii were distributed in open areas with low competition for light, between 80 and 800 m. These latter three species have the potential to become ornamental plants, being characterized by bright and colourful upright inflorescences. The data presented here will help in providing a valuable contribution to the conservation and use of the wild bananas in northern Viet Nam.
Functionalized SnO2 nanoparticles with gallic acid via green chemical approach for enhanced photocatalytic degradation of citalopram: synthesis, characterization and application to pharmaceutical wastewater treatment
Authors: Nazim Veronia S. , El-Sayed Ghada M. , Amer Sawsan M. , Nadim Ahmed H.
Published: August 2022

Eco-friendly stannic oxide nanoparticles functionalized with gallic acid (SnO2/GA NP) were synthesized and employed as a novel photocatalyst for the degradation of citalopram, a commonly prescribed antidepressant drug. SnO2/GA NP were characterized using high-resolution transmission electron microscopy, Fourier transform infrared spectroscopy, Brunauer–Emmett–Teller measurements and X-ray diffraction. A validated RP-HPLC assay was developed to monitor citalopram concentration in the presence of its degradation products. Full factorial design (24) was conducted to investigate the effect of irradiation time, pH, SnO2/GA NP loading and initial citalopram concentration on the efficiency of the photodegradation process. Citalopram initial concentration was found to be the most significant parameter followed by irradiation time and pH, respectively. At optimum conditions, 88.43 ± 0.7% degradation of citalopram (25.00 µg/mL) was obtained in 1 h using UV light (1.01 mW/cm2). Citalopram kinetics of degradation followed pseudo-first order rate with Kobs and t0.5 of − 0.037 min−1 and 18.73 min, respectively. The optimized protocol was successfully applied for treatment of water samples collected during different cleaning validation cycles of citalopram production lines. The reusability of SnO2/GA NP was studied for 3 cycles without significant loss in activity. This approach would provide a green and economic alternative for pharmaceutical wastewater treatment of organic pollutants.

Graphical abstract
On Processing Potato 3: Survey of Performances, Productivity and Losses in the Supply Chain
Authors: Haverkort A. J. , Linnemann A. R. , Struik P. C. , Wiskerke J. S. C.
Published: August 2022

Potato has strong links between the actors as varieties bred by breeders, crop management of growers and site location of processors strongly influence the yield and quality of the finished products. Here, the actors (breeders, growers, processors, retailers and users) in the value chain are recognized, and their information and material flows identified. The influence of genotype, environment and crop management and the efficient use of resources during the production of raw material, tubers harvested for processing purposes, are delineated. It is shown that climate change affects performance and that consumers looking for quality and new products are hardly interested in the primary processes, nor are breeders and processors showing interest in consumer concerns. Crop performance is dependent on yield and quality (dry matter, sugars, tuber size and desired and undesired constituents). Factory performance relies on recovery, reuse of rejects and avoidance of wastes. Heatmaps drawn of classes of productivity and losses and their attributes reveal where gains are to be made on fields, farms and factories to improve efficiencies, reduce the impact on the environment, and opportunities for decarbonisation.
Evolving fuzzy neural classifier that integrates uncertainty from human-expert feedback
Authors: de Campos Souza Paulo Vitor , Lughofer Edwin
Published: August 2022

Evolving fuzzy neural networks are models capable of solving complex problems in a wide variety of contexts. In general, the quality of the data evaluated by a model has a direct impact on the quality of the results. Some procedures can generate uncertainty during data collection, which can be identified by experts to choose more suitable forms of model training. This paper proposes the integration of expert input on labeling uncertainty into evolving fuzzy neural classifiers (EFNC) in an approach called EFNC-U. Uncertainty is considered in class label input provided by experts, who may not be entirely confident in their labeling or who may have limited experience with the application scenario for which the data is processed. Further, we aimed to create highly interpretable fuzzy classification rules to gain a better understanding of the process and thus to enable the user to elicit new knowledge from the model. To prove our technique, we performed binary pattern classification tests within two application scenarios, cyber invasion and fraud detection in auctions. By explicitly considering class label uncertainty in the update process of the EFNC-U, improved accuracy trend lines were achieved compared to fully (and blindly) updating the classifiers with uncertain data. Integration of (simulated) labeling uncertainty smaller than 20% led to similar accuracy trends as using the original streams (unaffected by uncertainty). This demonstrates the robustness of our approach up to this uncertainty level. Finally, interpretable rules were elicited for a particular application (auction fraud identification) with reduced (and thus readable) antecedent lengths and with certainty values in the consequent class labels. Additionally, an average expected uncertainty of the rules were elicited based on the uncertainty levels in those samples which formed the corresponding rules.