bluuebunny/crossref_metadata_2025 huggingface dataset:
Sociologia ambiental e ensino de sociologia: uma análise dos livros didáticos de sociologia para o ensino médio.
Authors:   , Josinaldo Soares Silva Antonio
Published: July 2023

Esta dissertação analisa os livros didáticos de Sociologia aprovados pelo Programa Nacional do Livro Didático (PNLD/2018), a partir da sociologia ambiental e de suas grandes tendências teóricas. A pesquisa justifica-se pela identificação de lacunas de estudos nessa temática e pela relevância em investigar como as questões ambientais se apresentam dentro desse material didático, legitimado e proposto para as escolas públicas e considerado um dos principais recursos de auxílio ao professor no desenvolvimento das mediações pedagógicas. Nessa perspectiva, este estudo se norteou a partir da seguinte questão: qual o lugar e o tratamento conferido à sociologia ambiental e seus aportes teóricos nos livros didáticos de Sociologia? Dentro desta questão, constituiu-se o principal objetivo do trabalho: identificar a sociologia ambiental nos livros didáticos de Sociologia aprovados pelo PNLD/2018 e descrever seu arcabouço teórico. A pesquisa se caracteriza como uma análise documental exploratória, com uma abordagem de natureza qualitativa e centrada na técnica de análise de conteúdo de Bardin (2009) via categorização. Para tanto, a sociologia ambiental compõe uma das categorias de análises, juntando-se a ela as suas perspectivas teóricas mais promissoras para o entendimento da relação sociedade-natureza e as origens das problemáticas socioambientais: conflitos ambientais, sociedade de risco, modernização ecológica e desenvolvimento sustentável. A pesquisa identificou certo esforço dos livros didáticos analisados, no sentido de abordar esse novo campo científico e as questões ambientais, mas de forma incipiente e com lacunas. Não há consenso entre as obras didáticas em relação ao conteúdo da sociologia ambiental que deve compor os seus programas de ensino, até mesmo a presença dessa disciplina não é certa, uma vez que nem todos os livros trazem de forma explícita os conteúdos pertencentes a esse campo. Por sua vez, compreende-se que as limitações observadas podem estar relacionadas à juventude dessa sociologia específica, a qual se encontra em processo de solidificação e expansão.
Implementasi Model Problem Based Learning Berbantuan Poster Matematika dalam Menyelesaikan Masalah Kaidah Pencacahan
Authors: Murtalib Murtalib , Mikrayanti Mikrayanti
Published: July 2023

Tujuan dari penelitian ini mendeskripsikan penerapan model Problem Based Learning Berbantuan poster dalam menyelesaikan masalah permutasi yang ditinjau dari aspek pengelolaan pembelajaran oleh guru, aktivitas siswa, ketuntasan belajar dan respon siswa. Subjek penelitian ini adalah siswa SMA Negeri 2 Bolo kelas XII semester ganjil. Penelitian ini merupakan penelitian deskriptif. Rancangan penelitian yang digunakan adalah One shoot case studi yaitu rancangan yang hanya memberikan perlakuan tertentu kepada sekelompok subjek tampa adanya kelompok kontrol dan tes awal, hanya melakukan tes setelah perlakuan. Instrumen pengumpulan data berupa lembar observasi untuk mendapatkan data pengelolaan pembelajaran oleh guru dan aktivitas siswa, lembar tes untuk ketuntasan belajar, dan angket untuk mengetahui respon siswa. Hasil penelitian menunjukan bahwa pengelolaan pembelajaran oleh guru menggunakan model Problem Based Learning berbantuan media poster dalam menyelesaikkan masalah kaidah pencacahan tergolong sangat baik; aktivitas siswa selama mengikuti pembelajaran dalam kategori sangat aktif; ketuntasan belajar klasikal siswa sebesar 85,16% tergolong baik; Respon siswa setelah mengikuti pembelajaran adalah sangat positif.
Significance Of Tumor Giant Cells In Oral Squamous Cell Carcinoma: A Case Report
Authors: KHAN SAMIHA
Published: July 2023

Background : Oral squamous cell carcinoma (OSCC) is the most common cancer of the oral cavity. OSCC presents with some typical histopathological characteristics like dysplastic epithelial cells with variable degrees of squamous differentiation. These histopathological features make it relatively easy to diagnose conventional squamous cell carcinoma. However, some cases show certain unique features that help in determining the prognosis of the disease. These features include epithelial-mesenchymal interaction, stromal hyalinization, clear cell change, stromal desmoplasia, perineural invasion, vascular invasion, tissue eosinophilia, giant cells and tertiary lymphoid follicle formation. The presence of giant cells in OSCC can be the result of foreign body reaction to keratin or due to formation of malignant tumor giant cells in poorly differentiated carcinomas. The giant cells showing pleomorphic features can be helpful in predicting the prognosis of the disease.
A Protocol For Analysis Of Variations In Maxillary Second Molar Bucco-Palatal Inclination In Cleft Lip And Palate Cases”
Authors: MATHEW JENI
Published: July 2023

Introduction : Facial abnormalities are effected in different facial region, the effect can be variable combination. Maxilla is generally affected in cleft cases, origin can be genetic or influenced by environment. Effected planes can be in three planes transverse, sagittal or vertical. Presurgical or postsurgical orthodontics is indicated in different cases. Presurgical orthodontics proponents emphasized correction of tooth has marked influence in retention and stability of results of interventions performed. In transverse plane it can be buccally or palatally inclined amongst different malocclusion. Our objectives were to evaluate maxillary second molar inclination in Angle’s Class I, Angle’s Class III malocclusion, and unilateral cleft lip and palate patients cases in transverse plane. Material and method : A systematic procedure was followed for the measurement of maxillary second molar inclination in Angle’s Class I, Angle’s Class III malocclusion, and unilateral cleft lip and palate patients. Maxillary second molar inclination was deliberated using protractor assembled on the surveyor. Expected Results : Inclination of second molar in unilateral cleft lip and palate and Class III malocclusion would be comparable. Conclusion : Corrections are performed in transverse plane first, thus emphasizing greater importance of buccopalatal inclination.
CONTRECOUP INJURY TO THE MANDIBLE – A CASE REPORT
Authors: PATIL SNEHA
Published: July 2023

Direct blow to the chin causes the hunting bow effect and transmits the blow to the condyle causing them to fracture. This is called as the contrecoup injury of the mandible. This report presents a case of 26-year-old male with left parasymphysis and bilateral condylar fracture. The treatment protocol followed was open reduction and internal fixation of left parasymphysis & right condylar fracture and closed reduction of left condylar fracture. In post-operative period, the patient did not experience any trismus, infection, sialocoele or wound dehiscence.
Investigation and comparison of technologies and methods of sulfur recovery and production processes
Authors: Kadyrov Sultan R.
Published: July 2023

Sulfur is found at the land's surface, in quarries, and as a natural sulfur resource. However, most of the part sulfur is obtained during the sulfur removal processes from crude oil or gas. These recovery processes are essential for the global energy resource market. Approaches to sulfur mining and recovering techniques are discussed and compared during the literature review and description analysis. Methods that are majorly used in the industry, their process flow diagrams, and principal of work are explained and compared relative to the modern methods of sulfur removal processes.
FEATURES OF CONDUCTING AN AUDIT ON REPORTS OF ILLEGAL ACQUISITION AND POSSESSION OF NARCOTIC DRUGS
Authors: Тактоева В.В.
Published: July 2023

В течение уже длительного времени в России остро стоит проблема наркотизации общества, в том числе и подрастающего поколения, негативно влияющая на здоровье не только отдельных граждан, но и нации в целом. В статье автор отмечает особенности проведения проверки по сообщениям о преступлениях, связанных с незаконным приобретением и хранением наркотических средств, обращает внимание на определенную последовательность проводимых проверочных мероприятий. Рассматриваются также процессуальные и тактические особенности проведения необходимых проверочных действий, проводимых по поступившему сообщению о преступлении, связанному с незаконным оборотом наркотических средств. Проводится анализ сложившейся судебно-следственной практики, проблемных вопросов, возникающих в процессе производства проверки на стадии возбуждения уголовного дела. Автором даются рекомендации о виде и тактике проведения проверочных действий в различных ситуациях, возникающих при выявлении рассматриваемого вида преступлений.

For a long time in Russia there has been an acute problem of drug addiction of society, including the younger generation, which negatively affects the health of not only individual citizens, but also the nation as a whole. In this article the author focuses on the peculiarities of drug proceeding, when proceeding by criminal complaint about illegal acquisition and possession of drugs, and pays attention to a certain sequence of verification activities. Procedural and tactical aspects of the necessary verification activities carried out on a report of a crime related to illicit drug trafficking are also considered. An analysis of the current judicial and investigative practice and the problematic issues arising in the process of verification at the stage of initiation of a criminal case is carried out. The author gives recommendations on the type and tactics of verification activities in various situations arising in the detection of this type of crime.
MALFUNCTIONS OF GAS HOSES AND THE OCCURRENCE OF EMERGENCY SITUATIONS. CAUSAL RELATIONSHIP
Authors: Синюк В.Д.
Published: July 2023

В статье освещаются проблемные вопросы установления причинно-следственной связи неисправности газовых шлангов бытовых плит с электрическим поджигом с возникновением пожаров и взрывов топливно-воздушных смесей. Дана уголовно-правовая оценка таким происшествиям на основе конкретных примеров из экспертной практики. Приведены рекомендации следственно-оперативным органам по работе непосредственно на местах пожаров и взрывов с целью всестороннего исследования места происшествия.

The article highlights the problematic issues of establishing the involvement of gas stoves with electric ignition in the occurrence of fires and explosions of fuel-air mixtures. A criminal-legal assessment of such incidents is given, based on specific examples from expert practice. Recommendations are given to investigative and operational bodies to work directly at the sites of fires and explosions, with the aim of a comprehensive investigation of the scene.
Ciúme, Violência Conjugal e Saúde Mental: Prevalência e Fatores Associados
Authors: Chaves Lemos Dayse da Silva , Falcke Denise , Lima de Oliveira Eduarda
Published: July 2023

O ciúme e a violência conjugal são fenômenos complexos que precisam ser melhor compreendidos, especialmente no que se refere às suas repercussões na saúde mental. O presente estudo teve por objetivo mensurar a associação entre ciúme, violência conjugal e saúde mental (ansiedade, depressão e estresse). Participaram 194 pessoas, sendo 151 mulheres e 43 homens, com idade de 19 a 58 anos, casados ou em união estável. Os instrumentos foram: questionário sociodemográfico, Revised Conflict Tactics Scale, Interpersonal Jealousy Scale, Inventário de Ciúme Romântico e Escala de Ansiedade, Depressão e Estresse. Constatou-se alta prevalência de violência, chegando a índices de 85,4% de homens que admitem cometer agressão psicológica em seu relacionamento. Destaca-se maior prevalência do ciúme, violência conjugal e adoecimento mental em pessoas com menor escolaridade e renda, sem união oficializada e sem filhos. É importante que esses fatores sejam observados como de risco para ocorrência da violência conjugal e suas repercussões.
A Twelve-Tone Repertory for Guitar: Julian Bream and the British Serialists, 1956–1983
Authors: Chandler Oliver
Published: July 2023

While the history of the formation of a modern British guitar repertoire around the central figure of Julian Bream is known in broad brushstrokes, we lack a thoroughgoing, technical understanding of the particular idiom that Bream’s composers developed. Important in the nascent stages of the guitar’s modernist evolution, for example, was its relationship to twelve-tone serialism. Through close readings of individual works by Reginald Smith Brindle (El Polifemo de oro, 1956), Denis ApIvor (Variations, 1958), Thomas Wilson (Three Pieces, 1961; Soliloquy, 1969), and Richard Rodney Bennett (Impromptus, 1968; Sonata, 1983), I map the formation of a peculiarly British vein of dodecaphony. To varying extents, these composers adapted or rejected the techniques, systems, and/or aesthetics of the Second Viennese and Darmstadt schools in order to arrive at a more moderate compositional approach. But despite this common cause, their approaches to composing dodecaphonically on the guitar differed substantially: ApIvor and Bennett attempted to build their twelve-tone materials around the guitar’s affordances; Smith Brindle and Wilson saved idiomatic sonorities and playing techniques for moments in which twelve-tone logic was to be purposefully overridden. By exploring the foregoing ideas and themes analytically, I attempt to demonstrate, in as musical a way as possible, how some of the most pressing compositional questions of the mid-twentieth century—Is twelve-tone serialism the only way forward? Is musical tradition dead in the water?—were responded to by composers crucial to the guitar’s modernist legacy.
Correlations between the Topography-Induced Gravity, Terrain Structure and the Seismicity in the Gulf of Panama
Authors: Lemenkova Polina , Debeir Olivier
Published: July 2023

This study presents new maps of the topographic and geophysical setting and seismicity in the region of the Gulf of Panama. The spatial analysis is based on the comparative analysis of the datasets on geoid, free-air gravity anomaly, topography and earthquakes. The cartographic framework is developed using the Generic Mapping Tools (GMT) scripting toolset. Seismic activity in the Central America is high due to the complex geologic setting, tectonic activity and lithosphere plate subduction. The data include the Earth Gravitational Model (EGM2008), the General Bathymetric Chart of the Oceans (GEBCO) and gravity grids. The seismicity data were collected from the Incorporated Research Institutions for Seismology (IRIS) catalogue on 1970–2021. The variations in data were compared to analyse correlations between the geophysical, seismic and topographic parameters. Free-air gravity, geoid and topographic data derived from the high-resolution datasets were used to investigate their effects on the main seismic sources in the region. The comparison of the maps showed that the distribution of the shallow earthquakes in the Pacific segment of Panama coincides with negative free-air anomalies and lower geoid values. The results revealed high values of geoid in the high mountainous regions of Panama (Cordilliera de Talamanca, southern coast of Peninsula de Azuero and eastern Panama, 77.5–78.5°W), which correspond to the topographic roughness in the highlands. Negative values of geoid are found over the Caribbean Sea basin (−4 to 0 m). The analyses of seismicity showed 1740 earthquake events varying by magnitudes from 2.9 to 7.8 at the depths up to 225 m (near the west coast of Colombia). A high concentration of the earthquakes is in the western region of the Panama’s shelf waters (~82–83.5°W), and on the border with Colombia (~77–78.5°W). High gravity anomalies (over 220 mGal) are found in the mountainous regions which match the geodynamic processes associated with the Earth structure and geodetic and geophysical effects. The regions of the high seismicity were defined in the Gulf of Chiriqui and eastern part of the Gulf of Panama.
Intervensi Promosi Kesehatan Pada Ibu Hamil Dan Ibu Balita Dalam Pencegahan Stunting
Authors: Khairunnisa Cut , Sidrah Nadira Cut , Rizky Simanjuntak Muhammad , Rifki Ramadhan Oriza
Published: July 2023

Stunting is a big problem in Aceh Province, especially North Aceh. Where North Aceh became one of the districts that became the locus of stunting. From 40,762 children under five in 2021 in North Aceh, the number of stunting reached 5,845 people. This figure reaches 45 percent of the total toddlers. West Reuleut is one of the villages in Muara Batu District which has a fluctuating stunting rate from year to year. Generally the incidence of stunting occurs due to poor parenting, mother's knowledge about how to do proper parenting is still very limited. The mechanism for implementing this service is by providing health promotion interventions to pregnant women and mothers with toddlers regarding the prevention of stunting since the first 1000 days of life. The implementation of the educational intervention was carried out by counseling using audio-visual media to pregnant women and mothers of toddlers as well as the practice of compiling menus for toddlers, pregnant women and breastfeeding mothers as well as monitoring and evaluation to establish relationships and find out the development of partnerships in implementing stunting prevention in the village of West Reuleut. After the end of this service activity, it was concluded that there was an increase in knowledge of pregnant women and mothers of children under five about stunting prevention efforts since the first 1000 days of life. Based on statistical tests, it shows that the health promotion interventions provided have an influence in increasing the knowledge of pregnant women and mothers of children under five. This increase in knowledge is expected to reduce the incidence of stunting, especially in the village of West Reuleut.
Hubungan Faktor Lingkungan Fisik Dengan Kualitas Hidup Penderita Diabetes Mellitus
Authors: Sepriani Tania
Published: July 2023

Diabetes Mellitus (DM) is a chronic disease that can affect the quality of life. One of the factors that affect the quality of life is the physical environment, such as temperature, light, and distance from the house to the road. This study aims to analyze the relationship between temperature, light, and house with the road on the quality of life of people with DM. Methods: This study used a cross-sectional design. The sample in this study amounted to 117 people using a purposive sampling technique. It was conducted using the WHOQoL-BREF questionnaire, temperature observations with a thermohygrometer, light using a luxmeter, and the distance from house to road using a roll meter. The strength of the correlation between variables was analyzed using the Chi-Square test. Results: There was a significant relationship between bedroom temperature (p= 0.000), bedroom light (p= 0.004), family room temperature (p= 0.000), family room light (p= 0.005), and distance from house to house. roads (p = 0.000) = 0.018) with the quality of life of DM patients. Conclusion: It can be concluded that the bedroom temperature, bedroom light, family room temperature, family room light, and distance from the house to the road are not eligible can affect the quality of life of people with DM. It is recommended for the community to be able to maintain, adjust, and optimize the physical environment.
Deteksi Pornografi pada Karakter Animasi 2D dengan KNN (K-Nearest Neighbors) Menggunakan Fitur HSV
Authors: Mayasari Candra Nur , Soeleman M. Arief , Pujiono Pujiono
Published: July 2023

The development of animation technology is very rapid, both in 2D and 3D forms. Most animators often create female animated characters for various fields such as games, commercials or other anime. Along with the development of animation, there are also negative and positive impacts, where the negative impact is the presence of symbols that lead to pornography. Most of the animations containing negative symbols are spread through the internet, which can be accessed easily by anyone, regardless of age. Which can result in addiction to viewing pornography to other negative behaviors. Artificial intelligence, which is currently developing rapidly, also allows this research to aim at early detection of animated characters that contain pornographic elements. By classifying 2D female animation using the KNN algorithm method with HSV feature extraction. The HSV feature is quite good at detecting complex colors in 2D animated characters. Where the HSV feature can distinguish skin color from other colors in 2D animation. The dataset used consists of 3 categories, namely pornographic images, semi-pornographic images, and non-pornographic images. Using the KNN method, it is possible to classify pornographic, semi-pornographic and non-pornographic images. In this study, the results of HSV feature extraction using the KNN classification method obtained the highest accuracy value of 63.16%.
Upaya Pemulihan Pendapatan Nasional Sektor Pariwisata Melalui Kebijakan Fiskal di Indonesia Pasca Pandemi
Authors: Alifiah Dinhaq Lubis Aisyah , Kustiawati Dedek , Fadlia Elvantio Reka , Sundari Sri
Published: July 2023

The tourism sector is a contributor to state revenue in the form of foreign exchange and plays a role in increasing productivity and reducing unemployment. The existence of COVID-19 has greatly affected the balance of national income, which has decreased. The sectors most affected are transportation, travel, warehouses and the accommodation and food provision sector. Then the other sector is the tourism sector in Indonesia, about 11.83% of Indonesian workers are in the tourism industry sector. The purpose of this study is to review the impact of Covid -19 which has resulted in the decline of the tourism industry sector in Indonesia and also to respond to Government policies to handle the impact The existence of health quarantine policies, social distancing and Large-Scale Social Restrictions (PSBB) greatly affects the activities of the tourism and manufacturing sectors which causes economic growth to slow down so that national income declines. Tourism is one of the sectors most affected by the Covid-19 pandemic. The tourism sector is the mainstay sector of the national economy that has the potential to encourage economic growth in Indonesia. This is indicated by the increase in the development of foreign tourist arrivals, foreign exchange receipts from the tourism sector, and the contribution of the tourism sector to national GDP. Reduced labor force, unemployment and poverty will increase will cause state revenues in the form of income tax (PPh) to decrease, therefore there needs to be a strategy for economic recovery in the tourism sector, namely fiscal policy. Fiscal policy is one of the economic policies launched by a country to manage and direct the economy to a more conducive condition. The way that this economic policy is highlighted is by changing or updating the management of state revenues and expenditures. This study uses a qualitative descriptive method and the data for this research is based on library research in the form of books, literature, journals, articles about the tourism industry, and how to recover in the post-pandemic, namely fiscal policy. Data obtained through the Central Statistics Agency regarding the development of tourism before and after the pandemic.
Pemberian Sanksi Dalam Perceraian Adat di Desa Inerie, Kecamatan Inerie, Kabupaten Ngada
Authors: Engelberti Bupu Maria , Hedewata Agustinus , Mauritsius Darius
Published: July 2023

Waja merupakan upaya pemutusan hubungan perkawinan adat karena salah satu pihak melakukan kesalahan ataupun keduanya telah bersepakat untuk berpisah. Waja juga merupakan suatu upaya untuk mengurangi dan meredahkan konflik yang terjadi dalam hubungan perkawinan. Waja dianggap dapat mengurangi dan meredahkan konflik karena waja itu sendiri dalam masyarakat adat Bajawa dianggap sebagai sebuah pengadilan resmi yang dapat mengesahkan perceraian yang telah terjadi. Penelitian ini bertujuan untuk mengetahui bilamana pemberian sanksi dalam perceraian adat di Desa Inerie, Kecamatan Inerie, Kabupaten Ngada dilaksanakan dan jenis sanksi yang diberikan dalam perceraian adat di Desa Inerie, Kecamatan Inerie, Kabupaten Ngada. Metode penelitian yang digunakan dalam penelitian ini adalah penelitian hukum empiris. Adapun sumber dan jenis data dalam penelitian ini adalah data primer yang diperoleh dari hasil studi lapangan dengan wawancara. Data sekunder diperoleh dari studi kepustakaan. Data yang diperoleh kemudian diolah dengan cara memeriksa dan mengoreksi data. Setelah data diolah kemudian dianalisis secara kualitatif. Berdasarkan hasil penelitian dan pembahasan maka dapat disimpulkan bahwa Waja/mozo dilaksanakan ketika pasangan yang sudah sah secara perkawinan adat melakukan pelanggaran terhadap perjanjian-perjanjian dalam perkawinan dan memilih untuk tidak melanjutkan perkawinan untuk disahkan secara agama. Dalam rangkaian pelaksanaan waja, ada ritual yang disebut dengan nata rogho to deka bhela bhai dan diikuti dengan sebhe kepe. Sanksi adat yang diberikan dalam waja adalah sanksi materil, yaitu berupa hewan (kuda/kerbau) untuk laki-laki yang melanggar perjanjan kawin dan yang ingin berpisah. Untuk perempuan yang melanggar perjanjian kawin dan ingin berpisah maka dikenakan sanksi berupa hewan (kuda/kerbau) dan pengembalian mahar yang telah diberikan oleh laki-laki pada saat perkawinan adat.
Analisis Waktu Penyediaan Berkas Rekam Medis Rawat Jalan di Rumah Sakit Setia Mitra Jakarta Selatan
Authors: Agustini Hudiyati
Published: July 2023

Provision of medical record files must be able to support health services, including outpatient services at hospitals. The time for providing medical record files since the old patient registered has a service standard of 10 minutes or less. The purpose of this study was to find out when to provide outpatient medical record files at Setia Mitra Hospital.

The research design used was observative and quantitative descriptive, with a total sample of 98 medical record files taken by random sampling. The results showed that the average provision of outpatient medical record files was 11 minutes, of which 0 files (0%) within 1−5 minutes, 43 files (43.9%) within 6−10 minutes, 49 files (50.0%) within 11−15%, and 6 files (6.1%) within 16−20 minutes. Factors causing this delay include disruption to the network connection on the TMU printer machine and registration computer, misplaced files (miss files), and the lack of socialization and evaluation of the SPO which regulates the time for providing medical record files.

Keywords : delays, provision, time line, outpatient medical record file.
Principio de oralidad en las audiencias virtuales de los procesos de interdicto de retener y la carga procesal en el juzgado civil de Chincha 2020
Authors:   , De La Cruz Pacheco Katherine Elizabeth , Tasayco Romero Erika Faniola
Published: July 2023

La investigación desarrolla el principio de la Oralidad en las audiencias virtuales en el proceso de interdicto de retener y la carga procesal en el juzgado civil de la provincia de Chincha. En estos tiempos que actualmente vivimos como es la pandemia del Covid 19, el Poder Judicial ha dispuesto que todos los juzgados lleven a cabo sus audiencias de forma virtual. Es así que en el proceso de interdicto de retener en la vía sumarísima desarrolla la Audiencia de Saneamiento, Prueba y Sentencia a través de la audiencia virtual mediante el cual se aplica el principio de la Oralidad en todo el transcurso de la Audiencia. El objetivo general de la investigación en base al planteamiento del problema es poder determinar ¿cuál es la relación que existe entre el principio de oralidad en las audiencias virtuales de los procesos de interdicto de retener y la carga procesal en el juzgado civil de Chincha 2020? Asimismo, la investigación es de tipo cualitativo, tiene un nivel descriptivo y de igual manera tiene un diseño no experimental basada en el desarrollo de los resultados obtenidos de la encuesta realizada a los abogados litigantes y a los servidores jurisdiccionales del Juzgado Civil de la Provincia de Chincha
Perilaku Bidan dalam Penggunaan APD pada APN di Wilayah Kerja Ranting Ibi Pedes Kabupaten Karawang Tahun 2022
Authors: Sari Nina Yuliana , Halimatusyadiah Leni , Octavia Rina
Published: July 2023

The aim of the study was to determine the behavior analysis of midwives in using personal protective equipment in normal delivery care in the 2022 IBI Pedes Karawang Working Area. This study used an analytical method with a cross sectional design. A sample of 54 midwives was taken using the total sampling method and the research instrument used a questionnaire. Bivariate analysis used the chi square test with a value of p = ? 0.05. The results of the study stated that respondents whose behavior was 37% obedient, had good knowledge 44.4%, good attitude 44.4%, availability of complete tools 46.3%. The results of the bivariate analysis showed that there was a relationship between knowledge and behavior in using PPE (p=0.01), there was a relationship between attitude and behavior in using PPE (p=0.001), there was a relationship between the availability of tools and behavior in using PPE (p=0.001). Based on the results of the research, it is hoped that the IBI Pedes Branch can provide books, posters and provide guidance for midwives. It is hoped that all midwives can use the complete PPE.

 

Tujuan penelitian untuk mengetahui Analisis perilaku bidan dalam penggunaan alat pelindung diri pada asuhan persalinan normal di Wilayah Kerja Ranting IBI Pedes Karawang 2022. Penelitian ini menggunakan metode Analitik dengan rancangan Cross Sectional.  Jumlah sempel 54 orang bidan diambil dengan metoda total sampling dan instrument penelitian ini menggunakan kuesioner. Analisis bivariat menggunakan uji chi square dengan nilai p = ? 0,05. Hasil penelitian menyatakan bahwa responden yang Perilaku patuh 37%, pengetahuan nya baik 44,4%, sikap baik, 44,4%, ketersediaan alat yg lengkap 46,3%. Hasil analisis bivariat menunjukan ada hubungan antara pengetahuan dengan perilaku penggunaan APD (p=0,01), ada hubungan antara sikap dengan perilaku penggunaan APD (p=0,001), ada hubungan antara ketersediaan alat dengan perilaku penggunaan APD (p=0,001). Berdasarkan hasil penelitian diharapkan Ranting IBI Pedes dapat menyediakan buku-buku, poster serta mengadakan pembinaan bagi bidan, harapannya semua bidan dapat menggunakan APD secara lengkap.
Reedição do Mito de Sísifo? Desafios da psicoterapia familiar em situações judicializadas
Authors: Moreira Janice Strivieri Souza , Fava Maria Luiza Vieira , Branco Zenilda Barbosa Castelo
Published: July 2023

O presente artigo tem por objetivo tecer reflexões sobre os desafios e os limites na busca de alternativas para a atuação dos terapeutas de família, no atendimento de casos judicializados nas Varas de Família em Curitiba. Refere-se à atividade das autoras como grupo de trabalho na Associação Paranaense de Terapia Familiar — APRTF, que desde 2019 acolhe os casos em litígio encaminhados por determinação judicial a esta Instituição. Utilizou-se a abordagem sistêmica como aporte teórico de base, considerando que a complexidade dessas situações clínicas requer uma visão ampliada das relações intra e intersistêmicas. Recorreu-se ao Mito de Sísifo como metáfora que reflete a dinâmica estabelecida entre o sistema familiar, o Sistema de Justiça e as profissionais atuantes como terapeutas familiares. Percebe-se que a tônica dos litígios envolve um pensamento linear, onde sobressai a visão binária, mobilizando um raciocínio disjuntivo da problemática. Nesse sentido, demanda-se da atuação clínica, intervenções que rompam com a repetição e manutenção do litígio.
A música no candomblé: etnomusicologia no Ilê Axé Opô Aganjú, Bahia
Authors: Angela Lühning
Published: July 2023

Este livro de Angela Lühning é um testemunho de uma época que apresenta importantes aspectos relativos ao funcionamento do candomblé da nação nagô-ketu, religião presente nas diversas regiões do país. Ponto principal são as intrínsecas relações entre o repertório cantado nas cerimônias públicas e suas funções rituais. Realizadas no final dos anos 1980, as análises de cunho etnomusicológico constituem uma base para novas investigações que se proponham a entender os processos percorridos pelo candomblé ao longo destes 30 anos, incluindo possíveis mudanças. Uma religião em mudança pode revelar muito de um país que também se transforma, o que atesta a um livro como este sua contribuição para uma interpretação do Brasil.
Physical Activity for Health—Every Minute Counts
Authors: Katzmarzyk Peter T. , Jakicic John M.
Published: July 2023

This Viewpoint discusses the amount of physical activity recommended by the Physical Activity Guidelines for Americans, 2nd Edition, and how clinicians should use these recommendations to personalize and set achievable physical activity goals for their patients.
Nitrogen‐Rich Rigid Polybenzimidazole With Phosphoric Acid Shows Promising Electrochemical Activity and Stability for High‐Temperature Proton Exchange Membrane Fuel Cells
Authors: Gao Aolei , Wang Wenwen , Wang Peng , Wu Hongchao , Gong Chenliang , Wu Aogui , Wei Gongyi , Wang Lei
Published: July 2023

Polybenzimidazoles (PBIs) are the most promising binders for the catalyst layer (CL) in high‐temperature proton exchange membrane fuel cells (HT‐PEMFC). However, traditional commercial PBIs are not applied in binders because they do not enhance the electrochemical performance and because the related solvents are not environmentally friendly. In addition, proton transfer channels in PBIs are not investigated at the microscopic and atomic scales to date. In this study, a nitrogen‐rich rigid PBI binder containing pyridine, diazofluorene, and partially grafted nitrile (PBPBI‐3CN) is prepared with a functionalized structure, good thermal stability, and good solubility in an environmentally friendly solvent. A membrane electrode assembly (MEA) is fabricated with the PBPBI‐3CN binder, providing a high peak power density, low resistance, and good stability. The protonation, hydrogen bond networks, and platform for proton transfer are confirmed in the CLs. The protonation of PBPBI‐3CN occurs in two steps. First, some phosphoric acid (PA) molecules bind to nitrogen‐containing acidophilic groups via preliminary protonation; second, multiple PA molecules then interact with nitrogen‐containing acidophilic groups via further protonation. With protonation as the foundation, a sufficient amount of PA molecules form a hydrogen bond network, and proton transfer channels are established.
From Volumetric to Planar Multiplexing: Phase‐Coded Metasurfaces without the Bragg Effect
Authors: Chen Jia , Wang Dapeng , Si Guangyuan , Zhang Rongxin , Hwang Yongsop , Wang Xinjian , Zheng Jiaxin , Shen Mengzhe , Wang Qian , Lin Jiao
Published: July 2023

Metasurfaces consisting of planar subwavelength structures with minimal thickness are appealing to emerging technologies such as integrated optics and photonic chips for their small footprint and compatibility with sophisticated planar nanofabrication techniques. However, reduced dimensionality due to the 2D nature of a metasurface poses challenges to the adaptation of a few useful methods that have found great success with conventional optics in 3D space. For instance, Bragg diffraction is the foundation of the well‐established technique of phase‐coded multiplexing in volume holography. It relies on interference among the scattered waves from multiple layers across the thickness of a sample. In this work, despite losing the dimension in thickness, a metasurface is devised to experimentally demonstrate phase‐coded multiplexing by replacing free‐space light with a surface wave in its output. The in‐plane interference along the propagation of the surface wave resembles the Bragg diffraction, thus enabling phase‐coded multiplexing in the 2D design. An example of code‐based all‐optical routing is also achieved by using a multiplexed metasurface, which can find applications in photonic data processing and communications.
A Triphenylphosphine‐Based Microporous Polymer for a Wittig Reaction Cycle in the Solid State
Authors: Weigelt Vincent , Vogl Sarah , Schmidt Johannes , Thomas Arne
Published: July 2023

The Wittig reaction is a key step in industrial processes to synthesise large quantities of vitamin A and various other important chemicals that are used in daily life. This article presents a pathway to achieve the Wittig reaction in a solid network. A highly porous triphenylphosphine‐based polymer was applied as a solid Wittig reagent that undergoes, in a multi‐step cycle, in total six post‐synthetic modifications. This allowed for regeneration of the solid Wittig reagent and reuse for the same reaction cycle. Of particular industrial relevance is that the newly developed material also enables a simple way of separating the product by filtration. Therefore, additional costly and difficult separation and purification steps are no longer needed.
The Keto‐Switched Photocatalysis of Reconstructed Covalent Organic Frameworks for Efficient Hydrogen Evolution
Authors: Wu Shuhong , Li Chao , Wang Ying , Zhuang Yan , Pan Yi , Wen Na , Wang Shuo , Zhang Zizhong , Ding Zhenxin , Yuan Rusheng , Dai Wenxin , Fu Xianzhi , Long Jinlin
Published: July 2023

The keto‐switched photocatalysis of covalent organic frameworks (COFs) for efficient H2 evolution was reported for the first time by engineering, at a molecular level, the local structure and component of the skeletal building blocks. A series of imine‐linked BT‐COFs were synthesized by the Schiff‐base reaction of 1, 3, 5‐benzenetrialdehyde with diamines to demonstrate the structural reconstruction of enol to keto configurations by alkaline catalysis. The keto groups of the skeletal building blocks served as active injectors, where hot π‐electrons were provided to Pt nanoparticles (NPs) across a polyvinylpyrrolidone (PVP) insulting layer. The characterization results, together with density functional theory calculations, indicated clearly that the formation of keto‐injectors not only made the conduction band level more negative, but also led to an inhomogeneous charge distribution in the donor‐acceptor molecular building blocks to form a strong intramolecular built‐in electric field. As a result, visible‐light photocatalysis of TP‐COFs‐1 with one keto group in the skeletal building blocks was successfully enabled and achieved an impressive H2 evolution rate as high as 0.96 mmol g−1 h−1. Also, the photocatalytic H2 evolution rates of the reconstructed BT‐COFs‐2 and ‐3 with two and three keto‐injectors were significantly enhanced by alkaline post‐treatment.
Hydrogen online monitoring based on thermal conductivity for anaerobic microorganisms
Authors: Miebach Katharina , Finger Maurice , Scherer Alexandra Maria Katarina , Maaß Constantin Alexander , Büchs Jochen
Published: July 2023

H2‐producing microorganisms are a promising source of sustainable biohydrogen. However, most H2‐producing microorganisms are anaerobes, which are difficult to cultivate and characterize. While several methods for measuring H2 exist, common H2 sensors often require oxygen, making them unsuitable for anaerobic processes. Other sensors can often not be operated at high gas humidity. Thus, we applied thermal conductivity (TC) sensors and developed a parallelized, online H2 monitoring for time‐efficient characterization of H2 production by anaerobes. Since TC sensors are nonspecific for H2, the cross‐sensitivity of the sensors was evaluated regarding temperature, gas humidity, and CO2 concentrations. The systems' measurement range was validated with two anaerobes: a high H2‐producer (Clostridium pasteurianum) and a low H2‐producer (Phocaeicola vulgatus). Online monitoring of H2 production in shake flask cultivations was demonstrated, and H2 transfer rates were derived. Combined with online CO2 and pressure measurements, molar gas balances of the cultivations were closed, and an anaerobic respiration quotient was calculated. Thus, insight into the effect of medium components and inhibitory cultivation conditions on H2 production with the model anaerobes was gained. The presented online H2 monitoring method can accelerate the characterization of anaerobes for biohydrogen production and reveal metabolic changes without expensive equipment and offline analysis.
A retrospective real‐world experience of immunotherapy in patients with extensive stage small‐cell lung cancer
Authors: Qiu Guihuan , Wang Fei , Xie Xiaohong , Liu Ting , Zeng Chen , Chen Ziyao , Zhou Maolin , Deng Haiyi , Yang Yilin , Lin Xinqing , Xie Zhanhong , Sun Gengyun , Zhou Chengzhi , Liu Ming
Published: July 2023

Background

The treatment of extensive stage small‐cell lung cancer (ES‐SCLC) has only made modest progress in the past decade, with two immune checkpoint inhibitors (ICIs), atezolizumab and durvalumab, approved for the treatment of SCLC by January 2022. However, currently, there is limited real‐world data on ES‐SCLC patients received immunotherapy.

Methods

We retrospectively collected and analyzed the demographic and treatment data of ES‐SCLC patients at the First Affiliated Hospital of Guangzhou Medical University from January 2017 to January 2022. Survival and prognosis information was obtained through follow‐up.

Results

A total of 353 ES‐SCLC patients were included, of which 165 received immunotherapy combined with chemotherapy as the first‐line (FL) treatment (chemo‐immune group), and 188 received chemotherapy (chemotherapy group). The objective response rate (ORR) and disease control rate (DCR) of patients receiving immunotherapy as the FL treatment were better than the chemotherapy group (76.97% vs. 48.40%, p < 0.001, and 83.03% vs. 68.09%, p < 0.001). Moreover, the progression‐free survival (PFS) and overall survival (OS) of ES‐SCLC patients receiving immunotherapy as the FL treatment were better than the chemotherapy group (6.7 months vs. 5.1 months, p < 0.001, and 12.5 months vs. 11.2 months, p < 0.001). Furthermore, the OS of ES‐SCLC patients who received immunotherapy as second‐line treatment was better than that in the chemotherapy group (15.9 months vs. 12.9 months, p = 0.036).

Conclusion

ICIs combined with chemotherapy as the FL treatment could be beneficial to the ORR, DCR, PFS, and OS of ES‐SCLC patients. Furthermore, ES‐SCLC patients can benefit from ICIs in the second‐line treatment, even if they had not received ICIs in the FL treatment.
Preparation of Dual‐activity Enzyme‐metal‐nanoparticles Conjugate Catalysts for Cascade Processes
Authors: Palomo Jose M.
Published: July 2023

The fabrication of novel systems where enzymatic and metallic actives sites directly interact represents an elegant strategy for sustainable processes. One of the new strategies involves the in situ formation of metal nanoparticles on a protein network as scaffold. This biological entity is the key element because it conserves the biological catalytic efficiency and induces the final metallic nanoparticles generation on the structure. This method allows to obtain bifunctional enzyme‐metallic catalysts with excellent versatility and efficiency in a different reaction and experimental conditions. In this concept article, the relevant aspects in terms of fabrication of enzyme‐metal nanoparticles hybrids and recently reported examples of successful application in cascade processes will be described.
The Rise of Structurally Anisotropic Plasmonic Janus Gold Nanostars
Authors: Singh Prem , Kundu Koustav , Seçkin Sezer , Bhardwaj Keshav , König Tobias A. F. , Jaiswal Amit
Published: July 2023

Nanostructures intrinsically possessing two different structural or functional features, often called Janus nanoparticles, are emerging as a potential material for sensing, catalysis, and biomedical applications. Herein, we report the synthesis of plasmonic gold Janus nanostars (NSs) possessing a smooth concave pentagonal morphology with sharp tips and edges on one side and, contrastingly, a crumbled morphology on the other. The methodology reported herein for their synthesis – a single‐step growth reaction – is different from any other Janus nanoparticle preparation involving either template‐assisted growth or a masking technique. Interestingly, the coexistence of lower‐ and higher‐index facets was found in these Janus NSs. The general paradigm for synthesizing gold Janus NSs was investigated by understanding the kinetic control mechanism with the combinatorial effect of all the reagents responsible for the structure. The optical properties of the Janus NSs were realized by corelating their extinction spectra with the simulated data. The size‐dependent surface‐enhanced Raman scattering (SERS) activity of these Janus NSs was studied with 1,4‐BDT as the model analyte. Finite‐difference time‐domain simulations for differently sized particles revealed the distribution of electromagnetic hot‐spots over the particles resulting in enhancement of the SERS signal in a size‐dependent manner.
Asymmetric Transfer Hydrogenation as a Key Step in the Synthesis of the Phosphonic Acid Analogs of Aminocarboxylic Acids
Authors: Dinhof Tamara , Kalina Thomas , Stanković Toda , Braunsteiner Kristóf , Rohrbach Philipp , Turhan Ertan , Gradwohl Andreas , Königshofer Artur , Horak Jeannie , Pallitsch Katharina
Published: July 2023

α‐Aminophosphonic acids have a remarkably broad bioactivity spectrum. They can function as highly efficient transition state mimics for a variety of hydrolytic and angiotensin‐converting enzymes, which makes them interesting target structures for synthetic chemists. In particular, the phosphonic acid analogs to α‐aminocarboxylic acids (PaAAs) are potent enzyme inhibitors, but many of them are only available by chiral or enzymatic resolution; sometimes only one enantiomer is accessible, and several have never been prepared in enantiopure form at all. Today, a variety of methods to access enantiopure α‐aminophosphonic acids is known but none of the reported approaches can be generally applied for the synthesis of PaAAs. Here we show that the phosphonic acid analogs of many (proteinogenic) α‐amino acids become accessible by the catalytic, stereoselective asymmetric transfer hydrogenation (ATH) of α‐oxo‐phosphonates. The highly enantioenriched (enantiomeric excess (ee) ≥ 98 %) α‐hydroxyphosphonates obtained are important pharmaceutical building blocks in themselves and could be easily converted to α‐aminophosphonic acids in most studied cases. Even stereoselectively deuterated analogs became easily accessible from the same α‐oxo‐phosphonates using deuterated formic acid (DCO2H).
Deep Eutectic Solvents: An Eco‐friendly Design for Drug Engineering
Authors: Oyoun Feras , Toncheva Antoniya , Henríquez Luis Castillo , Grougnet Raphael , Laoutid Fouad , Mignet Nathalie , Alhareth Khair , Corvis Yohann
Published: July 2023

In the spirit of circular economy and sustainable chemistry, the use of environmentally friendly chemical products in pharmacy has become a hot topic. In recent years, organic solvents have been the subject of a great range of restriction policies due to their harmful effects on the environment and toxicity to human health. In parallel, deep eutectic solvents (DESs) have emerged as suitable greener solvents with beneficial environmental impacts and a rich palette of physicochemical advantages related to their low cost and biocompatibility. Additionally, DESs can enable remarkable solubilizing effect for several active pharmaceutical ingredients (APIs), thus forming therapeutic DESs (TheDESs). In this work, special attention is paid to DESs, presenting a precise definition, classification, methods of preparation, and characterization. A description of natural DESs (NaDESs), i. e., eutectic solvents present in natural sources, is also reported. Moreover, the present review article is the first one to detail the different approaches for judiciously selecting the constituents of DESs in order to minimize the number of experiments. The role of DESs in the biomedical and pharmaceutical sectors and their impact on the development of successful therapies are also discussed.