bluuebunny/crossref_metadata_2025 huggingface dataset:
Envisioning the Future of ChatGPT in Healthcare: Insights and Recommendations from a Systematic Identification of Influential Research and a Call for Papers
Authors: Sallam Malik , Al-Farajat Amwaj , Egger Jan
Published: February 2024

Background and Aims: ChatGPT represents the most popular and widely used generative artificial intelligence (AI) model that received significant attention in healthcare research. The aim of the current study was to assess the future trajectory of the needed research in this domain based on the recommendations of the top influential published records.

Materials and Methods: A systematic search was conducted on Scopus, Web of Science, and Google Scholar (27–30 November 2023) to identify the top ten ChatGPT-related published records in healthcare across the three databases. Classification of the records as “top” denoting high influence in the field was based on citation counts.

Results: A total of 22 unique records from 17 different journals representing 14 different publishers were identified as the top ChatGPT-related publications in healthcare subject. Based on the identified records’ recommendations, the following themes appeared as important areas to consider in future ChatGPT research in healthcare: improving healthcare education, improved efficiency of clinical processes (e.g., documentation), addressing ethical concerns (e.g., patient privacy and consent), supporting research tasks (e.g., data analysis, manuscript preparation), mitigating ChatGPT output biases, improving patient education and engagement, and developing standardized assessment protocols for ChatGPT utility in healthcare.

Conclusions: The current review highlighted key areas to be prioritized in assessment of ChatGPT utility in healthcare. Interdisciplinary collaborations and standardizing methodologies are needed to synthesize robust evidence in these studies. Based on these recommendations and the promising potential of ChatGPT on healthcare, JMJ launched a call for papers for a special issue entitled “Evaluating Generative AI-Based Models in Healthcare”.
Albuminurias funcionales: su etiología y patogenia
Authors:   , Maillard Porras Pedro
Published: February 2024

La albúmina en la orina puede presentarse en variadas circunstancias. Según las investigaciones modernas, toda orina normal contiene vestigios de albúmina, siendo necesario limitar el concepto de albuminuria a la presencia de la orina (por los medios ordinarios) de verdaderos cuerpos albuminoideos, pues las albumosas y peptonas, las nucleoalbúminas, cuerpos de Bence Jones no se incluyen en la acepción clínica de la albuminuria. Se tratará de la albúmina renal o verdadera, cuando la albúmina haya sido segregada en los riñones, y por lo contrario de albúmina falsa o accidental, cuan do en las vías urinarias superiores se mezclen a la orina exudados albuminosos, sangre, pus o linfa.
Colitis ulcerosa grave
Authors:   , Simón Raúl S.
Published: February 2024

La colitis ulcerosa grave es una entidad clínica perfectamente individualizada, caracterizada por una inflamación de la mucosa del colon, ulcerosa y supurada, con una infección inicial específica del intestino, o sin ella, con invasión bacteriana o tóxica de la pared del intestino y condicionada por - trastornos nutricios, nerviosos, alérgicos e inmunológicos.- Hay varias enfermedades que presentan lesiones ulcerosas en el colon como las disenterias amibiana y bacilar y la enterocolitis tuberculosa, y éntrelas enfermedades generales la anemia de hematíes falci formes y la uremia. Resta un grupo grande en el que - el agente etiológico no ha sido determinado y que - produce una inflamación ulcerosa difusa del colon, recibiendo el nombre de colitis ulcerosa idiopatica ó inespecífica, y por otros colitis gravis, colitis supurativa crónica y colitis tromboulcerosa.
Acción de algunos medicamentos sobre la respiración celular en el ser humano
Authors:   , Mazzulli Hector René
Published: February 2024

El origen de este estudio lo constituyen las investigaciones sobre la acción del ácido succínico en la respiración, realizados en el Instituto de la Academia Nacional de Medicina de Buenos Aires por Camponovo y Labourt, bajo el auspicio de Mariano R. Castex y, por otra parte, el método de examen del proceso de reducción de la oxihemoglobina in vivo, introducido por Vierodt a fines del siglo pasado y ampliamente usado durante estos últimos años por Ray y otros autotores en el análisis de varias cuestiones fisiológicas relacionadas con la respiración tisular y por Samuels en el estudio minucioso de la influencia del ciclo sexual sobre dicho fenómeno de reducción.
Media Sebagai Etalase Permodelan Karakter Remaja Melalui Program Pencari Bakat pada Televisi Nasional di Indonesia
Authors: Faris
Published: February 2024

The mass media, no longer appear in a simple form, no longer functions as a tool to help our needs and information only, but has turned into a new land in the economic and industrial fields, all messages are preached, no longer purely just a message without importance, but it has become an interest in itself. Various kinds of information conveyed through television can increase public knowledge of various kinds of existing problems at this time. Television is expected to be able to help the community's need for entertainment, the entertainment world today has a big influence on our society, this is because there are many reality shows on television. This one reality show, that is Indonesian idols are phenomenal. Indonesian idol participant must have a basic talent in the arts, especially in the art of music. Their existence was truly unexpected, in just a few months they have become famous, this event is very powerful so it becomes an entertaining spectacle. The conclusion that can be drawn by the author is, that characters who are informed by reality show programs or talent search programs tend to pushed good proximity factor, because of a sense of friendship and because of desire to be, what can be shown in the talent search program, which is used as a role model or idol on national television in Indonesia.
Efektivitas Metode Problem Based Learning Dengan Pembelajaran Saintifik Terhadap Hasil Belajar IPA Siswa Kelas V Di Kecamatan Suppa Kabupaten Pinrang
Authors: Hakiki Hakiki , Muhammadiah Mas'ud , Asdar Asdar
Published: February 2024

Pembelajaran yang baik apabila guru mampu mengelola kelas dengan pembelajaran yang inovatif dengan menggunkan metode pembelajaran yang dapat membuat siswa berusaha sendiri seperti  pada pembelajaran IPA dengan  menggunakan metode Problem Based Learning dan metode pembelajaran saintifik. Penelitian ini bertujuan untuk mengalisis efektivitas metode Based Learning dengan Pembelajaran saitifik terhadap hasil belajar. Penelitian ini menggunakan penelitian eksperimen semu, dengan menggunakan non equivalent control group design. Populasi dalam penelitian berjumlah 419 sampel  52 orang siswa. Data hasil  penelitian dikumpulkan dengan menggunakan angket dan observasi. Teknik analisis data yang digunakan yaitu SPSS versi 26 dengan Teknik analisis data Independent Sampel T-test ,analisis data terdiri dari uji normalitas, uji homogenitas dan uji t. Hasil penelitian menemukan nilai signifikansi sebesar 0,034 dengan kata lain yakni 0,034 < 0,05 sehingga H0 ditolak dan H1 diterima yakni ada perbedaan peningkatan hasil belajar IPA tentang organ pernapasan manusia antara siswa yang diajarkan dengan pembelajaran Problem Based Learning dengan yang diajarkan pembelajaran saintifik sehingga dapat disimpulkan bahwa terdapat perbedaan efektifitas antara kelas yang menerapkan metode pembelajaran Problem Based Learning dengan  kelas yang menerapkan metode pembelajaran saintifik terhadap hasil belajar kelas V di Kecamatan Suppa Kabupaten Pinrang.
Good learning if the teacher is able to manage the class with innovative learning using learning methods that can make students try on their own, such as in science learning using the Problem Based Learning method and scientific learning methods. This research aims to analyze the effectiveness of the Based Learning method with scientific learning on learning outcomes. This research uses quasi-experimental research, using a non-equivalent control group design. The population in the study amounted to 419 samples of 52 students. Research data was collected using questionnaires and observations. The data analysis technique used is SPSS version 26 with the Independent Sample T-test data analysis technique, data analysis consists of a normality test, homogeneity test and t test. The results of the research found a significance value of 0.034, in other words, namely 0.034 < 0.05, so H0 was rejected and H1 was accepted, namely that there was a difference in the increase in science learning outcomes regarding human respiratory organs between students taught Problem Based Learning and those taught scientific learning so it can be concluded that there is a difference in effectiveness between classes that apply the Problem Based Learning learning method and classes that apply scientific learning methods on class V learning outcomes in Suppa District, Pinrang Regency.
Peningkatan Kemampuan Menulis Esai Narasi Melalui Teknik Mind Mapping Pada Mata Pelajaran Bahasa Indonesia Di Era Merdeka Belajar Kelas V UPTD SD Negeri 53 Parepare
Authors: Hadijah Hadijah , Hamsiah Andi , Asdar Asdar
Published: February 2024

Penelitian bertujuan untuk mengetahui peningkatan aktivitas belajar siswa melalui penerapan teknik mind mapping dan untuk mendeskripsikan peningkatan kemampuan menulis Esai Narasi melalui penerapan teknik mind mapping pada siswa kelas V UPTD SD Negeri 53 Parepare. Penelitian ini menggunakan pendekatan kualitatif, metode deskriptif, bentuk penelitian tindakan kelas (PTK), . Hasil penilaian kemampuan menulis esai narasi dari base line sampai siklus II dengan skor rata-rata yaitu (61,1), (69), (81,18). Hasil penilaian Ketuntasan Belajar sampai siklus II yaitu siklus I (tuntas 43%, dan tidak tuntas 57%) dan untuk siklus II (tuntas 90% dan tidak tuntas 10%) Kesimpulan, proses pelaksanaan pembelajaran dan kemampuan menulis esai narasi melalu teknik mind mapping pada siswa kelas V mengalami peningkatan.
The purpose of this study to know the increase in student learning activities through the application of mind mapping techniques and to describe the improvement of the ability to write narrative essays through the application of mind mapping techniques at class V UPTD students SD Negeri 53 Parepare. This study used a qualitative approach with descriptive methods. The form of research is Classroom Action Research (PTK). The assessment results show that the ability to write narrative essays from the base line to cycle II with an average score of (61.1), (69), (81.18). The results of the Learning Completeness assessment until cycle II are cycle I (43% complete, and 57% incomplete) and for cycle II (90% complete and 10% incomplete). Based on the data obtained, it can be concluded that the learning implementation process and the ability to write narrative essays through the mind mapping technique have increased at class V UPTD students SD Negeri 53 Parepare.
Penguasaan Kosakata Dengan Keterampilan Menulis Karangan Deskripsi Dan Minat Menulis Pada Siswa Kelas V UPTD SD Negeri 73 Parepare
Authors: Hastuti Hastuti , Hamsiah Andi , Muhammadiah Mas'ud
Published: February 2024

Tujuan penelitian adalah untuk mengetahui hubungan keterampilan menulis karangan deskripsi dengan penguasaan kosakata siswa kelas V UPTD SD Negeri 73 Parepare dan hubungan keterampilan menulis karangan deskripsi dengan penguasaan kosakata siswa kelas V UPTD SD Negeri 73 Parepare. Jenis penelitian ini adalah penelitian kuantitatif dengan pendekatan korelasional. Jumlah sampel dalam penelitian ini adalah peserta didik kelas V UPTD SD Negeri 73 Parepare, sebanyak 25 peserta didik. Metode pengumpulan data yang digunakan yaitu tes dan angket, sedangkan teknik analisis data yang digunakan yaitu pendekatan statistik deskriptif dan analisis statistik inferensial. Berdasarkan hasil analisis data, (1) Berdasarkan hasil penelitian terdapat hubungan yang linear antara variable penguasaan kosakata dengan variable keterampilan menulis karangan deskriptif siswa, (2) Minat menulis berkorelasi positif degan keterampilan menulis karangan deskriptif siswa, (3) Pengasaan kosakata dan minat menulis secara bersama- sama mempengaruhi keterampilan menulis karangan deskriptif siswa.
The purpose of this study was to determine: (1) The relationship between descriptive essay writing skills and the vocabulary mastery of class V students at UPTD SD Negeri 73 Parepare, (2) The relationship between descriptive essay writing skills and vocabulary mastery of class V students at UPTD SD Negeri 73 Parepare. This type of research is quantitative research with a correlational approach. The number of samples in this research was class V students at UPTD SD Negeri 73 Parepare, totaling 25 students. The data collection methods used are tests and questionnaires, while the data analysis techniques used are descriptive statistical approaches and inferential statistical analysis. Based on the results of data analysis showed that: (1) There is a linear  relationship between the variable vocabulary mastery with variable descriptive essay writing skills of students, (2) Writing interest is positively correlated with students' descriptive essay writing skills, (3) Vocabulary mastery and writing interest together affect students' descriptive essay writing skills.
Penggunaan Media Angka Dalam Meningkatkan Kemampuan Berhitung Dan Berbahasa Di Tk Al Qur'an Al-Hikam Tunjung Burneh Bangkalan
Authors: Kasmiyah Kasmiyah , Purnamasari Hetty , Hanifah Sri Yuni
Published: February 2024

Penelitian ini memiliki beberapa rumusan masalah yaitu adakah peningkatan kemampuan berhitung dengan metode bermain berbantuan media angka?, dan bagaimana peningkatan kemampuan berhitung dengan metode bermain berbantuan media angka Di TK Al Qur'an Al-Hikam Tunjung Burneh Bangkalan. Tujuan penelitian untuk mengetahui peningkatan kemampuan berhitung dengan metode bermain berbantuan media angka Di TK Al Qur'an Al-Hikam Tunjung Burneh Bangkalan. Penelitian ini menggunakan pendekatan kuantitatif dan Hubungan korelasi peningkatan kemampuan berhitung dengan metode bermain berbantuan media angka secara signifikansi diperoleh 0.003 dimana nilai ini < 0.05 artinya secara signifikansi hubungan korelasi antara variabel sangat kuat. Ditinjau dari nilai korelasi atau pearson correlations hubungan peningkatan kemampuan berhitung dengan metode bermain berbantuan media angka diperoleh nilai sebesar 0.651 nilai ini menunjukkan besar dari korelasi antara variabel. Kesimpulannya nilai hubungan korelasi sebesar 65,1% sangat berkorelasi. Nilai R Square sebesar 0,424 dimana nilai ini memberikan informasi bahwa pengaruh atau efektivitas dari peningkatan kemampuan berhitung dengan metode bermain berbantuan media angka sebesar 0,424 atau 42,4 % sangat berpengaruh.
This research has several problem formulations, namely, is there an increase in numeracy skills using the playing method assisted by number media and how is the numeracy ability increased using the number media assisted playing method in the Al Qur'an Al-Hikam Tunjung Burneh Bangkalan Kindergarten?. The aim of the research is to determine the increase in ability counting using the playing method assisted by number media at the Al Qur'an Al-Hikam Tunjung Burneh Bangkalan Kindergarten. This research uses a quantitative approach and the correlation relationship between increasing numeracy skills with playing methods assisted by number media has a significance value of 0.003, where this value is <0.05, meaning that the correlation relationship between variables is very strong. Judging from the correlation value or Pearson correlations, the relationship between increasing numeracy skills with playing methods assisted by number media, a value of 0.651 is obtained. This value shows the magnitude of the correlation between the variables. In conclusion, the correlation value of 65.1% is highly correlated. The R Square value is 0.424, where this value provides information that the influence or effectiveness of increasing numeracy skills using playing methods assisted by number media is 0.424 or 42.4%, which is very influential.
A NOVEL INSIGHT ON THE ROLE OF HMGB1 AS A POTENTIAL BIOMARKER OF METABOLIC SYNDROME
Authors: S Lavanya , Varalakshmi V Sureka
Published: February 2024

The metabolic syndrome is a collection of conditions that increase your risk of coronary heart disease, diabetes, stroke, and other major health
issues. In India, the prevalence of MetS in adults would be 20% to 25%. The factors responsible for these difculties have not all yet been identied,
despite the fact that several processes have been explored. Various international organisations have suggested multiple MetS categories with
different focuses and diagnostic threshold values, including NCEP (National Cholesterol Education Program), ATP3 2005, WHO 1999, IDF
(International Diabetes Federation), and AHA/ NHLBI (2009). Finding a suitable indication and the corresponding appropriate cut-off values is
crucial for the early detection and prevention of MetS. HMGB1 is a multifunctional, non-histone nuclear protein that has been connected to a
variety of clinical conditions, from sepsis to ischemia, as a DNA chaperone and a damage-associated molecular pattern (DAMP) with immunestimulating capabilities. This review's purpose is to summarize the most recent information on HMGB1's role in METS problems.
A CLINICAL PROFILE OF NAIL PSORIASIS AND ITS ROLE AS A MARKER OF SEVERE DISEASE.
Authors: Priyadarshini Anuradha , Veeraraghavan Mahalakshmi , Raveendran Nivedita , Sundaram Murugan , Swaminathan Adikrishanan
Published: February 2024

Introduction: Nail psoriasis is seen in 50% of psoriasis patients and in upto 80% of psoriatic arthritis patients. Severe nail psoriasis leads to
signicant impairment of quality of life. The objectives of this study were to analyze the patterns of nail involvement and correlate the severity of
nail psoriasis with skin disease, duration, and joint involvement. Cross-sectional study done over Method: 2 years, at a tertiary care hospital at
Chennai, south India. Consecutive patients of psoriasis with psoriatic nail changes were included. Severity was assessed by psoriasis area severity
index (PASI) and nail psoriasis severity index (NAPSI) scoring. Relation between NAPSI and PASI, duration of disease, and psoriatic arthritis was
assessed. There were 103 psoriasis patients with nail involvement. Mean Results: age was 45 years (range 18 -60 years), male:female ratio 1.4:1.
PASI scored ranged from 0.2-18.8, median of 1.2 and mean was 3.5±4.3. Nail matrix changes were more frequent than nail bed changes. Subungual
hyperkeratosis was overall most common nding (73.8%) followed by pitting (63.1%) onycholysis (60.2%), longitudinal ridges (48.6%),
melanonychia (27.2%). Pathognomonic oil drop sign was seen in 10.7% and 20-nail dystrophy in 5.8%. NAPSI score ranged from 2-80, median
was 25.5, mean was 24.81 ±19.4. Psoriatic arthritis was present in 41 patients (39.8%). Positive correlation was seen between NAPSI and PASI,
and NAPSI and duration of disease. The relation between NAPSI and psoriatic arthritis was not signicant. Conclusion: Nail psoriasis can be a
marker of severe disease. Severity of nail psoriasis increases with time and with severe skin disease.
ACUTE LIVER FAILURE IN PEOPLE CONSUMING FAT BURNERS: A SYSTEMATIC REVIEW
Authors: Walia Sheilja , Aggarwal Anjana
Published: February 2024

Background The modern sedentary lifestyle has increased obesity rates due to decreased physical activity. Seeking effortless weight loss, many
people use fat burners, claiming to reduce weight. However, excessive use poses risks like palpitations, anxiety, hepatotoxicity and liver failure.
Studies are reporting that fat burners caused Acute Liver Failure (ALF) in many cases. The lack of regulations from the Food and Drug
Administration (FDA) regarding these products has contributed to their widespread consumption and increased risk of liver diseases. This review
aimed to attain a better understanding of available fat burners and document the cases of ALF caused by the consumption of these products.
Methods Electronic databases were systematically searched for relevant articles. Selection and screening were performed based on inclusion and
exclusion criteria. The case reports and series included in the nal list of the studies were assessed using the CARE guidelines. This review Results
included 33 studies that showed commonly used products were Hydroxycut, Garcinia Cambogia, Herbalife, Green tea extracts, Oxylite Pro etc.
The patients presented with symptoms of nausea, fatigue, jaundice and vomiting. More females (73%) were reported with ALF and mean age of 37
years. Most of the patients (56%) showed improvement in symptoms of ALF after discontinuation of the product. Conclusion Despite numerous
reports worldwide, evidence establishing a direct link between fat burners and ALF remains inadequate. Larger trials analyzing ingredients are
crucial to ll these evidential gaps.
ROLE OF DYNAMIC CT SCAN IN DIAGNOSING AND CHARACTERISING THE SOLID RENAL MASSES AND IT'S MIMICS AND COMPARISON WITH HISTOPATHOTHOLOGY.
Authors: Kumari Sangeeta , Nand Vidya , Agrawal Monika
Published: February 2024

Introduction: Renal tumours are common these days-Benign as well as malignant. Most of the malignant lesions are clear cell carcinoma
(ccRCC), followed by papillary RCC (pRCC). It is important to differentiate and characterise renal carcinomas and their mimics. In the present
research we did the dynamic evaluation of the renal tumours on CT, differentiated them on the basis of Enhancement pattern and compared with the
post-operative histopathological ndings as gold standard. Aims and Objective: Primary Objective:-To assess the sensitivity and specicity of
volume -based enhancement parameters like mean and median enhancement on dynamic contrast enhanced computed tomography (CECT) to
diagnose and characterise solid renal masses and compare with histopathology. Secondary Objective:-To assess the sensitivity and specicity of
dynamic CT scan in differentiating between Renal cell carcinoma and it's mimics. Materials and Methods: Our study was the prospective and
multicentric study. We did the study at two centres (MEDANTA hospital, Gurgaon and SRMS institute of medical sciences Bareilly, from: Feb
2015 to June 2016 and November 2020 to June 2023 respectively). Multiphasisc dynamic contrast CT imaging of the 75 patients was done .Images
in different phases were transferred to a dedicated workstation .The lesions were segmented and enhancement pattern were displayed as
histogram in different phases with the help of the softwere named generic in the Siemens CT scanner .Both quanlitative and quantitative study was
done. In the quantitative sections-mean and median enhancement values and parameters like skewness, kurtosis, standard deviation, and
interquartile range were calculated for each lesion. Enhacemnet pattern on the histogram were used to differentiate and characterise the solid renal
lesions. We were able to diagnose different type of renal lesions and different Conclusion: iate them. Larger number of patient was having renal cell
carcinoma predominantly clear cell(ccRCC) and papillary carcinoma(pRCC) on histopathology which showed different enhancement pattern, so
we were able to differentiate between clear cell(ccRCC) and papillary carnoma(pRCC) with almost 100 % sensitivity and 98% specicity.
EXPLORING THE COMPREHENSIVE LANDSCAPE OF ARTIFICIAL INTELLIGENCE IMPLEMENTATIONS IN PERIODONTICS: A REVIEW
Authors: Das Neelam , Addanki Pavan Kumar
Published: February 2024

The integration of Articial Intelligence (AI) into periodontics heralds a transformative era in dental medicine, offering unprecedented
opportunities for enhanced diagnostics, personalized treatment planning, and improved patient care. This review explores the multifaceted
applications of AI in periodontics, including advanced imaging analysis for early disease detection, predictive analytics for customized treatment
strategies, and the development of smart dental tools for effective patient monitoring and engagement. Despite the promising advancements, the
incorporation of AI in clinical practice is not without challenges, particularly concerning ethical considerations and data privacy. The future
directions of AI in periodontics encompass potential advancements in regenerative therapies and the integration with 3D printing technologies,
underscoring the need for continuous interdisciplinary collaboration to navigate the challenges and fully realize AI's potential in improving
periodontal health outcomes. This comprehensive review emphasizes the transformative impact of AI on periodontics, highlighting the importance
of addressing the ethical and regulatory challenges to harness the full benets of this technology in dental care.
KNOWLEDGE ABOUT DIABETES MELLITUS AMONG PHYSIOTHERAPY STUDENTS: A SURVEY STUDY
Authors: Rani Suman , Jagga Vinay
Published: February 2024

Introduction: As we know diabetes mellitus is common problem nowadays so Knowledge of diabetes mellitus and its risk factors are necessary for
primary healthcare in order to prevent co-morbidities that increase the burden of the disease. The knowledge, training and awareness of
physiotherapy students about diabetes is important because they will solve this public health problem in future. The objective of this Objective:
work is to strengthen the knowledge about diabetes among physiotherapy students. In this Material And Method: survey study a total of 120 third
year and nal year physiotherapy students from Baba Mastnath University, Asthal Bohar, Haryana were included. The purpose of the study was
explained to all participants. A 23-point "Brief Diabetes Knowledge Test " was completed in English. In this survey Result And Conclusion:
study total 120 physiotherapy students from third and nal year participated in which 89 (74.2%) students were with age of 19 to 22 years and 31
(25.8%) were of 23 to 26 years. Of the participants 45 (37.5%) were male, 75 (62.5%) were female. Data analysis shows that there was 6 (5%)
students with low knowledge of diabetes mellitus, 52 (43.3%) with average knowledge of diabetes mellitus and 62 (51.7%) with high knowledge of
diabetes mellitus. On applying chi- square test result shows that there was no signicant difference of diabetic knowledge between both age groups
students with p value o.286 that is more than level of signicance ( >0.05). Results also show that there was no signicant difference between male
and female students with the p value 0.803 that is also more than level of signicance (>0.05).
ADULT MIXED PHENOTYPE ACUTE LEUKEMIA IN A WESTERN INDIA
Authors: Shah Kajal , Panchal Harsha , Patel Apurva , Jain Kushboo , Ramawat Sandeep , Kokate Abhijeet
Published: February 2024

Background & objectives: Mixed-phenotype leukemia (MPAL) is a type of acute leukemia in which the blast population shows mixed features of
myeloid, T-lymphoid, and/or B-lymphoid differentiation. MPALs are rare and carry a poor prognosis because of both diagnostic and therapeutic
challenge. Conventionally, the diagnosis of MPAL requires either a single blast population with a lineage dening phenotypic expression of
multiple lineages (myeloid, B-cell and/or T-cell) (biphenotypic) or two distinct blast populations that each independently satisfy criteria for
designation as AML, B-ALL, and/or T-ALL (bilineage). This retrospective study was designed to study their clinicopathological presentation and
treatment outcome of MPAL cases in a tertiary care hospital in western India. To evaluate the clinicopathological characteristics and Aim:
treatment outcomes of patients with MPAL in a developing Low–Middle-Income country. A retrospective study of 24 adult patients Methods:
newly diagnosed with MPAL from January 2005 to December 2017. There were 8 female and 16 male. Aver Results: age age was 35 years old
(range = 19–78). Nine cases were biclonal and fteen were biphenotypic. There were 21 adult and 3 geriatric patients. There were T/Myeloid in 8
patients (33.3%) and B/Myeloid in 16 (66.7%). Two (8.3%) patients had MLL gene rearrangement, four (16.7%) had Philadelphia-positive
chromosomes, and two (8.3%) had FMS-like tyrosine kinase 3 (FLT3-ITD) internal tandem duplication (FLT3-ITD). The involvement of the CNS
at presentation was noted in 3 (12.5%) cases among 24 MPAL patients. Eighteen patients (75%) received acute lymphoblastic leukemia (ALL)
induction and thirteen patients (72.2%) achieved complete remission (CR) with no induction deaths. Therapy for four Ph1+ MPAL is based on an
ALL or AML protocol combined with tyrosine kinase inhibitor (TKI). Six patients (25%) started therapy with acute myeloid leukemia (AML)
induction: 3(50%) achieved CR. Five patients with ALL induction failure were switched to AML therapy. 5 year EFS 79.2% overall, 83.3% with
ALL directed treatment and 66.7% with AML directed treatment. Five patients were relapsed, three after ALL directed treatment and two after
AML directed treatment. ALL-directed therapy associated with better out Conclusion: come than AML directed therapy in adult MPAL patients in
our study.
ESOPHAGEAL DUPLICATION CYST IN A PATIENT WITH ISCHEMIC HEART DISEASE - A CASE REPORT
Authors: Gazdar Rohaan , Jayant Halder Premashish
Published: February 2024

Esophageal Duplication Cysts (EDC) are rare in adults, < 7% are symptomatic. About 90% do not communicate with the esophageal lumen.
Majority occur in the lower one-third of the esophagus. Minimally invasive surgery is the preferred treatment, with shorter hospital stays. [1, 2] A
53-year gentleman with coronary artery disease (CAD), presenting with retrosternal chest pain, was found to have a soft tissue lesion arising from
the right wall of the mid - esophagus on Computed tomography (CT) scan. Endoscopic ultrasonography (EUS) conrmed features of EDC. The
cyst was excised by Video Assisted Thoracoscopic Surgery (VATS). Patient had an uneventful recovery. Histopathology conrmed EDC.
MANAGEMENT OF INGUINAL HERNIA WITH BENIGN PROSTATIC HYPERPLASIA BY SIMULTANEOUS INGUINAL HERNIOPLASTY AND TRANSURETHRAL RESECTION OF PROSTATE
Authors: Prasad Om Prakash , Pandey Shruti , Prakash Praveen , Pathak Amrendra , Suman Neha
Published: February 2024

Introduction: Benign prostatic hyperplasia (BPH) is a common disease in elderly patients. As life expectancy is increasing day by day its
incidence is increasing, often it is manifested by symptoms of bladder outlet obstruction. Materials and methods: The study was conducted
prospectively at Hindu Rao hospital Delhi, in the period between Jun 2018 to Jun 2019 on 44patients presenting in the Surgery OPD, Urology OPD
and Surgical emergency. Atotal of 44 patients were studied. They were divided in to 3 groups: Group I- patients undergoing TURPand hernia in one
session (n=14), Group II- patients undergoing TURP alone (n=15) and Group III - patients undergoing hernia alone (n=15). The results were
analyzed to see whether the presentation of the two operations at the same time was a feasible option. Results: The mean time of surgery in the
TURP + Hernia arm was signicantly more than the other two arms of the study (p value <0.001). The average postoperative stay for patients with
the combined procedure was slightly lesser as compared to TURP alone (p value 0.177). There was no statistically signicant difference in
occurrence of complications among three groups. Conclusion: Combined operative procedure i.e. TURP and hernioplasty in single anesthesia for
concomitant pathology has the advantage of greater patient satisfaction, quick convalescence, decreased hospitalization and cost effectiveness.
FRUIT- VEGETABLES INTAKE AND PHYSICALACTIVITY ON THE RISK OF METABOLIC SYNDROME AMONG OBESE ADULTS IN URBAN, PUDUCHERRY.
Authors: K Vembu. , Kumari M J. , J Venkatachalam
Published: February 2024

Background In most countries, metabolic syndrome (MetS) affects roughly one-fth of the adult population, and its incidence is constantly
growing. MetS risk factors have been identied as inadequate physical activity (PA) and inadequate fruit and vegetable (FV) intake. Due to a lack
of research, the consequences of their association with MetS are unknown. The goal of this study was to investigate the independent and combined
effects of FV and PA on MetS. Methods A baseline study of weight reduction randomized controlled trial carried out using random sampling
among obese individuals in urban Puducherry, using WHO STEPS (version 3.2) questionnaire and fasting blood samples obtained from October
2022 to February 2023. MetS was dened using WHO criteria. The required sample size, according to Li tong X et al., is 306, however the current
study has 438 participants. To investigate the interactive effect of PA and FV on the MetS, an interaction test was performed using STATA 14.
Results MetS was found in 31.28% of subjects, with men and females having rates of 28.48% and 39.13%, respectively. In compared to their
counterparts, those with adequate FV intake had a considerably decreased risk of MetS (OR = 0.6, 95% CI: 0.32, 0.9), whereas those with adequate
PAhad an insignicantly lower risk of MetS (OR = 0.75, 95% CI: 0.5, 1.2). In the interaction test, interaction between PAand FV was a signicant
predictor of MetS (unadjusted model P = 0.0297, adjusted model p = 0.001). Conclusion Findings of the current study shows that the combination
of adequate FV intake and adequate PA was signicantly associated with reduced MetS risk among adult residents of Puducherry. Therefore
comprehensive intervention should be individualized based to each client with MetS.
A RETROSPECTIVE STUDY OF THE ETIOLOGY FOR LAPAROSCOPIC RIGHT HEMICOLECTOMY IN A TERTIARY CARE CENTRE FOR A PERIOD OF FIVE YEARS.
Authors: Deolekar Samir S , FS Raja Sanaah
Published: February 2024

Laparoscopic colorectal surgeries have changed the outlook to morbid diseases such as colon cancer. In the West right sided colon resections are
done mainly for neoplasms. However, in our country where tuberculosis is endemic, right sided colon resections are done for intestinal obstruction
due to Koch's Abdomen. Being the most frequently aficted site in intestinal tuberculosis, the ileo -caecal-ascending colon region develops
strictures and masses, leading to sub-acute intestinal obstruction which obviates surgery. Our study has demonstrated that in a zone endemic for
tuberculosis, majority of laparoscopic right hemicolectomy surgeries are done for the same, as opposed to neoplastic growth.
Dynamic interaction of the corticospinal tract with the reticulospinal tract across various phases of stroke
Authors: Kim Dongwon , O'Shea Leah M , Aghamohammadi Naveed
Published: February 2024

To date, the dynamic mechanisms by which the corticospinal tract (CST)
and its alternative tract (i.e. the reticulospinal tract (RST)) interact
and evolve after the CST has been damaged by stroke has not been fully
explored. To gain insight into the mechanisms, we construct a
computational model to reproduce several critical features of subscore
distributions of the Fugl-Meyer assessment (FMA) for the upper extremity
following stroke. Subscores of the FMA present clues about the working
neural substrates affected by stroke, potentially distinguishing
preferential uses of the CST and RST. A stochastic gradient descent
method is employed to emulate biologically plausible phenomena,
including activity- or use-dependent plasticity and the preferred use of
more strongly connected neural circuits. The model replicates several
segments of empirical evidence presented by imaging and
neurophysiological studies. One of the main predictions is that
substantial CST recovery is achievable unless the initial degree of
residual corticospinal neurons following stroke falls below a certain
level. Another prediction is that while the functional capabilities of
the CST and RST increase in a harmonic way post-stroke, the degrees of
functional capability those tracts reach are in a competitive
relationship. We confirm that the neural system prioritizes optimizing a
more strongly connected motor tract and uses the other tract in a
supplementary manner to enhance overall motor capability. This model
presents insights into efficient therapy designs.
Error correction of parity-encoding-based annealing through post-readout decoding
Authors: Nambu Yoshihiro
Published: February 2024

Lechner, Hauke, and Zoller proposed a parity-encoded spin-embedding
scheme for quantum annealing (QA) with all-to-all connectivity to avoid
the issue of limited connectivity in near-term QA hardware and to enable
the implementation thereof using only geometrically local interactions
between spins fabricated on the planar substrate. Nevertheless, the
redundant encoding of logical information, i.e., using a large number of
spins to embed the logical information, increases the computational cost
and reduces the efficiency. In this study, we show through Monte Carlo
simulation that this redundant encoding may be exploited to solve the
problems of the inefficiency and computational cost of the
parity-encoded scheme by incorporating appropriate decoding, namely
classical post-processing, of the spins to retrieve the logical
information. Our findings open up the possibility of parity-encoded
schemes for realizing the QA with near-term quantum technologies.
Come il dualismo della forma di governo italiana ha ritardato una riforma, al contrario, impellente per l’allora Quarta Repubblica francese
Authors: Montelatici Lapo
Published: February 2024

La forma di governo italiana e quella della Quarta Repubblica francese sono state più volte messe a confronto. I due Paesi sperimentano, infatti, le medesime preoccupazioni di fondo, fornendo ad esse le medesime soluzioni. Tuttavia, l’Italia rinuncia fin da subito ad impostare la propria forma di governo su basi monistiche, attribuendo alla presidenza della Repubblica un ruolo chiave nella gestione dei fievoli equilibri post-Seconda Guerra Mondiale. Il presidente della Repubblica italiano si trova, così, a gestire un alto tasso di conflittualità, al quale le poche razionalizzazioni incidenti sul rapporto di fiducia, da un lato, e l’assenza di una diversa legislazione elettorale, dall’altro, difficilmente possono porre rimedio. Altrimenti detto, l’Italia, a differenza della Quarta Repubblica francese, attribuisce alla propria forma di governo un’anima dualista, rimandando, al contempo, non solo una riforma sostanziale del proprio sistema politico, ma anche la percezione che ciò possa essere necessario.

 

Several times, the form of government of Italy and the form of government of the French Fourth Republic have been compared. Indeed, Italy and the French Fourth Republic experience the same essential concerns, finding the same solutions. However, Italy gives up restarting its own form of government on monism, giving the President of the Republic a key role in the handling of the Post-World War II feeble balance. So, the Italian President of the Republic ends up handling a high rate of conflict, which a few rationalizations influencing the vote of confidence, on one side, and the lack of a different electoral legislation, on the other, could not remedy. In other words, Italy, unlike the French Fourth Republic, gives its own form of government a dualist being, postponing, at the same time, not only a substantial reform of its own political system, but also the perception that it could be necessary.
La “Giustizia digitale” tra nuove forme di efficienza e garanzia dei diritti costituzionali
Authors: Longo Erik
Published: February 2024

L’articolo indaga le molteplici intersezioni tra l’intelligenza artificiale (IA) e la giustizia concentrandosi sulle implicazioni legate agli usi delle più recenti forme di IA come ChatGPT nei processi giudiziari. Dopo aver introdotto i Large Language Models, sono presi in esame l’uso amatoriale di ChatGPT nelle procedure legali, evidenziando benefici potenziali, come il miglioramento dell’efficienza e dell’efficacia delle decisioni, e i rischi riguardanti la trasparenza, la protezione dei dati personali, l’indipendenza della magistratura e il diritto a un processo equo. La parte centrale dell’articolo esplora due documenti istituzionali volti a governare lo sviluppo della giustizia digitale e affronta le decisioni umane assistite dall’IA. Nel paragrafo finale si riflette sull’alba di una nuova forma di giustizia, con un’enfasi sul bilanciamento tra progressi tecnologici e la protezione dei diritti costituzionali.   

The article explores the nexus of artificial intelligence (AI) and justice, focusing on the impact of advanced AI technologies like ChatGPT on judicial processes. It begins by introducing Large Language Models, then delves into the amateur application of ChatGPT in legal settings, outlining potential benefits for efficiency and decision-making quality, alongside risks concerning transparency, personal data security, judicial independence, and the right to a fair trial. The core discussion revolves around two institutional documents aimed at steering the evolution of digital justice, touching on AI-supported human decision-making. The conclusion contemplates the emergence of a novel justice form, emphasizing the need to reconcile technological progress with constitutional rights safeguarding.
رقابة السلطة التنفيذية على أعمال البرلمان
Authors: الحسيني محمد
Published: February 2024

يمكن تقسيم أعمال البرلمان إلى ثلاثة انواع، عملان رئيسان يدخلان في صلب وظيفة المجلس النيابي، وهما التشريع والرقابة على أعمال السلطة التنفيذية، أما العمل الثالث فهو العمل الإداري، ويمكن عده عملا تنظيميا يدير البرلمان شؤونه من خلاله، وفي الانظمة التي تتبنى مبدأ الفصل المرن بين السلطات، للسلطة التنفيذية فرض رقابتها على واحد من الأعمال الثلاثة فقط، مستخدمة بعض الوسائل التي تتيح لها فرض رقابتها عليه.
الأوضاع الاقتصـــادية (1929-1932) وانعكاسها على الوضع السياسي الداخلي النمساوي
Authors: عبد الرزاق احمد , عبد علي زهراء
Published: February 2024

شهدت الولايات المتحدة الأمريكية ابتداء من عام 1929 أزمة اقتصادية وقد اختلفت تلك الآزمة عن سابقاتها ليس بمدتها فحسب، بل بعمقها واتساعها وتأثيرها فلم تقتصر على الولايات المتحدة الأمريكية ,انما شملت معظم الدول الاوربية سواء اكانت زراعية ام صناعية. وذلك بفضل الترابط الاقتصادي الحاصل بين الدول العالم, والدور الهام الذي اخذت تلعبه الولايات المتحدة الأمريكية في الاقتصاد العالمي بعد الحرب العالمية الاولى اذ سرعان ما انتشرت عدواها في اقل من ثالثة سنوات. كانت النمسا واحد من أكثر الدول ضررا فيها لما تعانيه من عجز مالي ووضع اقتصادي منهار عقب هزيمتها في الحرب العالمية الاولى.
أثر الاستثمار الرأسمالي على الاستدامة المالية لشركات القطاع الخدمي بحث تحليلي لعينة من الشركات المدرجة في بورصة عمان للأوراق المالية للفترة 2008-2020
Authors: الحمداني رافعة , احمد محمد
Published: February 2024

هدف البحث إلى قياس أثر الاستثمار الرأسمالي على الاستدامة المالية لشركات القطاع الخدمي لعينة من الشركات العقارية التابعة للقطاع الخدمي والمسجلة في بورصة عمان للأوراق المالية للفترة 2008-2020 وقد تضمنت البيانات المطلوبة للدراسة على بعض المؤشرات المالية التي بوساطتها سيتم بناء النماذج القياسية واختبار فرضيات البحث متمثلة بـ(الأرباح الموزعة, الأرباح المحتجزة, الموجودات الثابتة, إجمالي الموجودات, إجمالي المطلوبات, صافي الربح بعد الضرائب والفوائد أو العائد, إجمالي حقوق الملكية, المطلوبات طويلة الآجل, صافي الدخل, إجمالي دوران الموجودات, الأرباح قبل الفوائد والضرائب). وتم استخدام صيغة دوبونت DuPont لقياس الاستدامة المالية التي تمثل المتغير التابع, أما لقياس أثر الاستثمار الرأسمالي فتم بوساطة ثلاثة متغيرات مستقلة (X1): يمثل نسبة العائد إلى الموجودات الثابتة و(X2): يمثل نسبة الموجودات الثابتة إلى إجمالي الموجودات، و(X3): يمثل نسبة الموجودات الثابتة إلى إجمالي المطلوبات.
أثر هيكل رأس المال في الأداء المالي للمصارف الاسلامية في العراق دراسة لعينة من المصارف المدرجة في سوق العراق للأوراق المالية للفترة (2005-2017)
Authors: البدري سندس , عبد الصاحب علاء
Published: February 2024

هدفت هذه الدراسة إلى التعرف على طبيعة العَلاقة بين هيكل راس المال والأداء المالي للمصارف التجارية عينة الدراسة والمدرجة ضمن سوق العراق للأوراق المالية.

وتجسدت مشكلة الدراسة في التساؤلات الاتية:

ما هي الأساليب التي تتبعها المصارف الاسلامية في صياغة هيكل رأس المال فيها؟

هل يوجد تأثير ذو دلالة معنوية لهيكل رأس المال على الأداء المالي المصرفي؟

إذ تم استخدام ثلاثة من أهم المؤشرات المعبرة عن هيكل راس المال (المتغيرات المستقلة) متمثلة بـ (اجمالي المطلوبات إلى حق الملكية, اجمالي المطلوبات إلى اجمالي الموجودات, حق الملكية إلى اجمالي الموجودات) وثلاثة مؤشرات للأداء المالي المصرفي (المتغيرات التابعة) متمثلة بـ (معدل العائد على حق الملكية , معـدل العائد على الموجودات , نصيب السهم من الارباح الصافية) , وتم اختيار اثنين من المصارف الاسلامية العراقية المدرجة في سوق العراق للأوراق المالية عينة للدراسة.
الأداء والتأويل والتفسير والفرق بينهما
Authors: الاعرجي مهند , كاظم ميس
Published: February 2024

هدف البحث للتعرف الى مفهوم الأداء والتأويل والتفسير والفرق بينهما, ومعرفة الأداء التأويلي, وتأتي أهمية البحث الى العلاقة بين الأداء والتأويل لأن الأداء التأويلي  هو صرف اللفظ عن المعنى الراجح إلى المعنى المرجوح لدليل يقترن به, وهذا يفرض وجود غموض في النص الديني يستلزم ذلك , وتأتي أهمية البحث لمعرفة الفرق بين التفسير والتأويل , وبيان معنى كل منهما في المعجمات اللغوية والاصطلاحات الفقهية , وتكمن مشكلة البحث في السؤال الآتي : ما الأداء والتأويل  والتفسير؟ وما الفرق بينهما؟ ولغرض الاجابة على السؤال الرئيسي قامت الباحثة بتقسيم البحث الى ثلاثة مباحث درس المبحث الأول الأداء والتأويل والتفسير والفرق بينهما, ودرس المبحث الثاني التفسير لغة واصطللاحا, أما المبحث الثالث فقد درس العلاقة بين التفسير والتأويل وشروط التأويل, وتوصل البحث الى عدة نتائج ومن أهمها: يجب أن تكون صيغة النص قابلة للتأويل كالظاهر, وليس مفسرا ولا محكماً, وأن يقوم دليل يؤيد صحة صرف النص عن معناه الظاهر الى المعنى المرجوع المحتمل.
النفس والروح في الفكر الإسلامي تفسير الميزان للسيد محمد حسين الطباطبائي أنموذجاً
Authors: الاعرجي مهند , هاشم مروة
Published: February 2024

تناول المفكرون الإسلاميون مفردتي النفس والروح، ومنهم الفارابي وابن سينا، وبينوا أن النفس جوهر روحاني مستقل عن آلتها لكونها لا تدرك ذاتها بدون آلة، وأن الروح ما هي إلا حالة من حالاتها، وهي النفس الناطقة.

وبما ان البحث الذي نحن بصددهِ يتقصى مفردتي النفس والروح في القرآن الكريم، فقد أرتايت أن يكون القرآن الكريم هو الرافد الأول والأساسي للبحث عن مفردتي النفس والروح على رأي المفسر محمد حسين الطباطبائي. فيتبين من ذلك إن الهدف من البحث هو لتمييز الفرق بين النفس والروح من حيث الدلالة في الاستعمال القرآني.
Cost-benefit Analysis and Financial Feasibility of Rosemary Production in Southern Ethiopia
Authors: Tilaye Melkamu , Bukero Guta
Published: February 2024

This study was conducted at Wondo Genet Agricultural Research Center experimental field from January 2018 to March 2021. The study examined the financial feasibility of WG-Rosemary-III rosemary variety for fresh herbs and WG-Rosemary-II rosemary variety for dry herb production. For this study, both rosemary varieties were planted on 100m2 land areas with an intra and inter-row spacing of 60cm. All cost and benefit data were collected during the cultivation period. The study utilized financial analysis methods such as net present value (NPV) and benefit-cost ratio (BCR) to analyze the feasibility of their production. The study found that the net present value of production of WG-rosemary-III for fresh herbs was ETB 2,603,219.63 per hectare in its entire three years of production, indicating that its production is financially feasible. The benefit-cost ratio of production of WG-rosemary-III for fresh herbs was 7.94 which indicates that a 1 ETB outlay for this rosemary production results in a net return of ETB 6.94 per hectare. Besides, the net present value of production of WG-rosemary-II for dry herb was ETB 1,186,051.02 per hectare in its entire three-year course of production, which indicates that its production is financially feasible. The benefit-cost ratio of production of WG-rosemary-II for dry herbs was 4.22 which indicates that a 1 ETB outlay for this rosemary production results to gain a net return of ETB 3.22. The results indicate that the production of these rosemary varieties is profitable. Therefore, the government and other concerned stakeholders should further scale up the production of these rosemary technologies through training and awareness creation for farmers and investors through extension agents, thereby these rosemary technologies are utilized as a significant source of income and contribute to the enhancement of household well-being.