bluuebunny/crossref_metadata_2025 huggingface dataset:
АZƏRBАYCАN-NАTО ƏMƏKDАŞLIĞININ PЕRSPЕKTİVLƏRİ
Authors: А.А. Bаdirkhаnоv  , E.K. Mеhdiyеv
Published: April 2024

Bеynəlxаlq аləmdə nüfuzu gеtdikcə аrtаn müstəqil Аzərbаycаn Rеspublikаsı qlоbаl prоsеslərdə və yеni dünyа nizаmının qurulmаsındа söz sаhibi оlаn NАTО ilə əlаqələrin inkişаfınа önəm vеrir, qаrşılıqlı münаsibətlərin bərаbərhüquqlu tərəfdаşlıq səviyyəsində inkişаfını dəstəkləyir. Bu gün bеynəlxаlq еkspеrtlər rеgiоnаl və qlоbаl təhlükəsizliyin birgəlik prinsipi çərçivəsində təmin еdilməsi, mənаfеlərin qоrunmаsı və qаzаnılmış təcrübələrin pаylаşılmаsı istiqаmətində Аzərbаycаnın аtdığı аddımlаrı yüksək qiymətləndirirlər. Ölkəmizlə NАTО-nun siyаsi priоritеtləri və təhlükəsizlik sаhəsindəki mаrаqlаrı üstüstə düşür. Tərəflərаrаsı münаsibətlərin dаhа dа yаxınlаşdırılmаsı bölgədə sülh və təhlükəsizliyin təmin оlunmаsının bаşlıcа qаrаntıdır.
XANKƏNDİ ŞƏHƏRİNDƏ UCALAN ŞANLI BAYRAQ DOSTA GÜVƏN, DÜŞMƏNDƏ QORXU YARADIR
Authors: S.A. Bagirov  , E.S. Jabbarov
Published: April 2024

Xankəndi şəhərində dalğalanmaqda olan şanlı bayraq, yerli əhali arasında dosta güvən və milli birliyi simgələyir. Bu bayraq, müstəqil dövlətin mövcudluğunu və müstəqilliyini qoruyan simvolik bir ifadədir. Onun yüksəkəldiyi hər an, milli gururun artmasına və dostlara olan etimadın güclənməsinə səbəb olur. Əksər təbirlərlə, şanlı bayraqlar milli mənfəət və vətəndaşlıq hisslərinin bir araya gəldiyi simvolik nümayişlərdir. Bu bayrağın dalğalanması, yerli əhaliyə güvən və güclü bir milli birlik hissi verməkdə, müstəqil dövlətin simvolu olaraq özünü təqdim etməkdə əhəmiyyətli rolu oynayır.
AZƏRBAYCAN RESPUBLİKASININ QONŞU DÖVLƏTLƏR İLƏ HƏRBİ ƏMƏKDAŞLIĞI
Authors: S.A. Bagirov  , А.А. Bаdirkhаnоv
Published: April 2024

Hər bir ölkənin təhlükəsizliyi və inkişaf göstəricilərini həm də qonşuları ilə münasibətləri müəyyən edir. Hansı ölkə ki, qonşularla siyasi konfliktlər yaşamır, isti əlaqələrə malikdir və əməkdaşlıq edir, həmin ölkə təhlükəsizliyi və davamlı inkişafı üçün əlavə avantaj qazanmış olur. Bu cür əlaqələr regionun da taleyinə təsir edir.Azərbaycanın xarici siyasətində bu prinsip aydın ifadə olunur qonşularla əməkdaşlıq əlaqələrinin möhkəmləndirilməsi və şaxələndirilməsi. Qlobal miqyasda etibarlı tərəfdaş kimi nüfuz qazanan Azərbaycan regionun lokomotivi olaraq yüksək reputasiyaya sahibdir. Rəsmi Bakı, təbii olaraq, işğalçı Ermənistan istisna olmaqla, yerləşdiyi regionun bütün ölkələri ilə müxtəlif platformalarda iki və çoxtərəfli əməkdaşlıq əlaqələrinə malikdir. Bu, özünü siyasi münasibətlərdə də, xarici ticarət dövriyyəsində də göstərir.
The Prosecutor's Office in the unified system of public authority
Authors: Ul'yanov Aleksandr
Published: April 2024

The monograph is devoted to the study of the place and role of the prosecutor's office in the system of state power in the context of historical development, as well as through the prism of constitutional reforms and transformations that affected the main status characteristics of this institution and determined the features of its constitutionalization. The work provides a constitutional and legal characteristic of the Russian model of the prosecutor's office, which has no analogues in world practice. In the light of constitutional amendments, attention is paid to the problem of determining the legal status of the prosecutor's office in the system of public power, as well as the search for optimal criteria for assessing the effectiveness of the activities of this department. The publication may be of interest to scientists and practitioners, scientists, teachers, applicants and graduate students, undergraduates and students of higher educational institutions, as well as other readers interested in this issue.
Participation in a 2-year weekly phone surveillance system: results from Lesotho
Authors: Lethoko Molibeli , Chang Christiana , Badu Teshawna , Farley Shannon M. , Chen Qixuan , Greenleaf Abigail R.
Published: April 2024

Interest in cell phones as a valid survey mode in sub–Saharan Africa increased precipitously in the past decade. However, the mode has mainly been used for cross-sectional studies. This paper presents enrollment and participation rates for a two-year (July 2020 – June 2022), weekly population-based computer-assisted telephone interview (CATI) surveillance system in Lesotho. We found high participation and share lessons learned.
VERNACULAR ARCHITECTURE OF JODHPUR: A RESILIENT APPROACH TO SUSTAINABLE ENVIRONMENT
Authors: Baghel Aruna , Mehta Priyanka , Agrawal Anshu
Published: April 2024

Sustainable architecture is the application of principles that contribute in the evolution of building designs and processes that reduce the negative environmental effects of construction. When contemplating Jodhpur's vernacular architecture, it becomes clear that traditional construction methods correspond to basic green design principles such as using energy-efficient locally available materials and resources. Many traditional aspects of Jodhpur architecture can be easily incorporated into contemporary environments to provide a sustainable atmosphere and natural accompaniment. This study presents the scope of eco-friendly development of the city by using traditional construction techniques and materials, built forms, and fabric with a thorough analysis of the hot and dry climate of the area. It also encompasses the use of this local architecture to help create an energy- efficient thermal comfort zone in similar climatic conditions in any part of the world. This work is an attempt to reclaim the ideals about good architecture towards this setting, in not only terms of identifying the hot and arid climate but also in terms of producing a design philosophy relevant to the manner of living in a conventional city.
PROPAGANDA IN AIADMK'S 2021 CAMPAIGN SONG: A MULTIMODAL DISCOURSE ANALYSIS
Authors: G V Neelambari , Jeyapal Balasubramaniam
Published: April 2024

Campaign songs have long been utilized to communicate political parties’ ideas and promote unity, particularly in the political landscape of Tamil Nadu. However, recent election campaigns have leveraged advancements in technology and innovative multimedia marketing techniques, giving campaign songs a distinct significance for shaping public opinion and swaying voters. This study examines the campaign song “Thodarattum Vetrinadai Endrendrum Eratailai” (May the success continue forever for two leaves) released by the All-India Anna Dravida Munnetra Kazhagam (AIADMK) party during the 2021 Tamil Nadu state legislative election. Employing multimodal discourse analysis and Kress and Van Leeuwen’s visual grammar, the research analyzes the song’s content to identify the presence of propaganda techniques. The study reveals that Bandwagon, Plain Folk, and Card Stacking are prominent propaganda tools employed in the song. Furthermore, the visual grammar analysis unveils the strategic use of visual elements in the video that synchronously aligns with the party’s campaign objectives.
Atıksuların Yeniden Kullanımına Genel Bir Bakış
Authors: Fırat Betül , Sericik Sevgi , Çakmak Yakup , Uğuzlu Sultan , Demir Özlem
Published: April 2024

Dünya nüfusunun dörtte biri suyun fiziksel olarak kıt olduğu yerlerde yaşamakta ve küresel olarak her üç kişiden biri su kıtlığına katlanmaktadır. Sürdürülemez tüketim seviyeleri, yerel su kıtlığına yol açmış ve tatlı su ekosistemlerini önemli ölçüde etkilemiştir. Nüfus artışı ve endüstrinin gelişmesinden kaynaklanan artan su taleplerini karşılamak mevcut su kaynaklarını azaltmaktadır. Birçok kurak ve yarı kurak alanda endüstriyel, tarımsal, rekreasyonel ve içme uygulamaları için gerekli olan büyük miktarda suyu sağlamak zordur. Uygun arıtma yoluyla geri kazanılan atıksu, çeşitli su kalitesi gereksinimlerini karşılayabilmektedir. Geri kazanılmış su, arıtma seviyesine bağlı olarak tarımsal ve peyzaj sulama, endüstriyel işlemler, tuvalet yıkama ve yeraltı suyu havzasının yenilenmesi gibi birçok su talebini karşılamak için çok sayıda uygulama kullanılabilir. Nüfuslar artmaya devam ettiği sürece genel su dengesi kontrol altında tutulmalıdır. Daha fazla insan daha fazla tatlı su anlamına gelir, bu da daha fazla atıksu anlamına gelmektedir. Dünyanın artan su ihtiyaçlarına verebilecek tek çözümün su geri dönüşümü olduğu bilinci her geçen gün artmaktadır. Bu çalışmada dünya genelinde ve Türkiye’de mevcut bulunan su potansiyeline, suyun geri kazanımının önemine, atıksuların geri kazanım tekniklerine, arıtılmış atıksuların yeniden kullanımı ile ilgili yapılan bazı çalışmalara ve halkın görüşüne yer verilmiştir. Yapılan çalışmalar göstermiştir ki atıksuların geri kazanımı çeşitli arıtım yöntemleri ile mümkün olmaktadır fakat arıtılmış atıksuların yeniden kullanımı ile ilgili daha fazla çalışmaya ihtiyaç duyulmaktadır.
Application of the Reliability Centred Maintenance Method at QGS in PT ABC Dumai
Authors: Melliana Melliana
Published: April 2024

QGS A1 is a powerful crusher and dryer designed based on reference drying equipment with good performance efficiency. It has a very important function in expediting the production process, but this tool often breaks down, which really affects smooth production. In connection with the damage to the tool, it needs to be examined to find out what maintenance should be done. This study aims to find out earlier the damage that affects the smooth production so that it can be known what maintenance actions must be carried out. This study uses the Reliability-Centered Maintenance method, which utilizes information on reliability and weaknesses as well as a list of maintenance actions to choose from. The results of this study found a solution: the QGS A1 treatment run to failure was 81.2%, the direct condition was 18.18%, and the failure finding was 0%.
Optimization of Cardamom Fruit (Amomum compactum) Extraction Focused on Total Terpenoid Extraction and Cytotoxic Activity Using Response Surface Methodology
Authors: Juliana Dara , Priosoeryanto Bambang Pontjo , Nurcholis Waras
Published: April 2024

Cardamom is one of the medicinal plants called perennial herbs from the Zingiberaceae family. Cardamom, with the scientific name Amomum compactum, contains various phytochemical compounds such as terpenoids, flavonoids, phenolics, tannins, sterols, and proteins that are pharmacologically useful as an anticancer, antioxidant, and have cytotoxic activity. Testing the total content of terpenoid compounds that affect the cytotoxic activity of A. compactum fruit using Box-Behnken Design with three independent variables (solvent ratio, ethanol concentration, and extraction time) has never been studied before. Thus, this study aimed to obtain the extraction optimization conditions on the total terpenoid content and cytotoxic activity using Artemia salina Leach larvae with the response surface method, namely Box-Behnken Design with Design Expert 13.0 application. Determination of the total terpenoid content of the A. compactum fruit extract was carried out based on the standard ursalic acid, and the cytotoxic activity was carried out using the Brine Shrimp Lethality Test (BSLT) method. The maximum total terpenoid obtained was 4.8970 mg UAE/g DW, and the minimum IC50 value was 38.8813 ppm. Optimal conditions for the extraction of A. compactum fruit obtained a combination of 1:8 mL/g solvent ratio, 50% ethanol concentration, and extraction time of 1 day with a desirability value of 0.772. Furthermore, the optimal extraction solution results from the Box-Behnken Design were verified and analyzed using a One-Sample T-Test. Using the Box-Behnken Design extraction optimization method, the content of terpenoid bioactive compounds with cytotoxic activity from A. compactum fruit can be optimally obtained.
Caminata de 6 minutos y espirometría en pacientes recuperados de enfermedad grave y crítica por COVID-19
Authors: Cuevas Acuña María Tula , Mancilla  Hernández Eleazar , León-Vázquez Maria de la Luz
Published: April 2024

Objetivo: Evaluar la función pulmonar mediante espirometría y la prueba 6MWT en pacientes recuperados de enfermedad grave y crítica por coronavirus (COVID-19).
Métodos: Estudio observacional, transversal y descriptivo, que incluyó pacientes entre 2 y 6 meses después de padecer enfermedad grave y crítica por COVID-19. Previo consentimiento, se les realizó espirometría y 6MWT, y se les aplicó la Escala Funcional post-COVID- 19 (PCFS). Para el análisis de los datos se utilizó estadística descriptiva e inferencial con el programa SPSS versión 24.
Resultados: Se registraron 40 pacientes; 40% mujeres, con edad 53 ± 14 años; 82.5% mostraron algún grado de sobrepeso u obesidad, y 72.5% padecía alguna comorbilidad. Mediante la PCFS 77.5% de los pacientes tuvo algún grado de limitación. En la 6MWT, la distancia recorrida fue de 426.3 ± 123.9 m vs 530.57 ± 93.7 m esperados, con descenso en la saturación de oxígeno, disnea y fatiga (p < 0.05). La capacidad vital forzada y el índice valor de capacidad vital forzada/volumen espiratorio forzado en el primer segundo (FEV1 /FVC) fue menor al esperado.
Conclusiones: La espirometría y 6MWT son pruebas disponibles que pueden implementarse en la evaluación de pacientes recuperados por enfermedad grave y crítica por COVID-19. De acuerdo con el estudio, los pacientes caminan distancias menores a la esperada, con disminución en la saturación de oxígeno, disnea y fatiga.
Palabras clave: Espirometría; 6MWT; COVID-19; SARS-COV-2; Secuelas por enfermedad grave y crítica por COVID-19.
La enfermedad crónica bajo la urticaria: más allá del prurito
Authors: Moreno Lozano Lucía , De Aramburu Mera , Bermúdez-Hormigo Carmen
Published: April 2024

Introduction:
Short-lasting erythematous-papular skin rashes suggest a clinical diagnosis of urticaria. However, it may be another type of dermatitis whose diagnosis may require complementary examinations.
 
Case report: 53-year-old woman diagnosed in 2016 with diffuse large B-cell lymphoma in complete remission. Since 2010 she presented daily episodes of erythematous-papular lesions lasting 24-36 hours. She was treated with antihistamines, oral corticosteroids and Omalizumab without control.
 
A study was carried out consisting of:
Blood tests: haemogram, serum immunoglobulins, thyroid hormones, complement, cryoglobulins, proteinogram, autoimmunity markers. Of note: positive ANA 1/320 mitotic nuclear pattern.
Skin biopsy (x2) compatible with dermatitis herpetiformis.
Celiac disease antibodies and HLA DQA1 and DQB1 locus. HLA-DQ2 positive DQ2.5 in heterozygosis.
Discussion: Dermatitis herpetiformis was diagnosed and a gluten-free diet and dapsone were indicated with good control, highlighting the importance of differential diagnosis of papular exanthema.
Revisión de registros históricos de los ácaros del polvo doméstico en países del Pacífico y Caribe continental en Latinoamérica
Authors: Acuna-Cantillo Luis , Humberto Maldonado-Santana  , Óscar Calderón-Llosa
Published: April 2024

Introduction: The house dust mites are allergen source that trigger allergies symptoms. In Pacific and Caribbean continental countries various species are prevalent in domestic environment and include in the allergy tests. However, its altitudinal and geographic distribution is unknown.
Objective: Review the historical records of house dust mites in the countries of the Pacific and continental Caribbean of Latin America.
Methods: A systematic review was carried out, adapting the PRISMA method, in digital repositories using a combination of the terms in Spanish: “ácaros domésticos” “alergia” and in English: “dust mites” “allergy” with the names of the countries “Costa Rica”. “Panama” “Venezuela” “Colombia” “Ecuador” “Peru” between 1970-2022. The inclusion criteria were presence of the mite species, city or municipality, country, height above sea level and year. A database was built in Microsoft Excel Office 365®. Maps were created using QGIS 3.30 geographic information systems and descriptive statistics were used to analyze the findings.
Results: From the search and identification, 3959 references were obtained, of which 133 were considered potentially eligible, of these 45 met inclusion criteria, and only 32 presented records of domestic mite species. Historically there were 424 records and 27 species (18 genera and 9 families). The countries with the most studies and records were Colombia (14 and 242), Panama (8 and 64) and Peru (5 and 74). 66% (281/424) of the records were of the species Dermatophagoides pteronyssinus (81), followed by Blomia tropicalis (58), D. farinae (40), Chortoglyphus arcuatus (39), Cheyletus sp. (33) and Euroglyphus maynei (30). The species with the greatest altitudinal range were D. pteronyssinus, (2-4800 m.a.s.l) and E. maynei (2- 3399 m.a.s.l).
Conclusions: A synthesis was presented on the historical geographical and altitudinal distribution of house dust mites in countries of the Pacific and continental Caribbean of Latin America, which in turn allowed us to determine the species with the greatest records, highlighting those of importance in allergology. These findings are an input for acarological surveillance in public health.
 
Keywords: Dust mite allergy, Caribbean, Pacific, Records, Review.
Serie de casos de pacientes con angioedema hereditario y uso de ácido tranexámico como tratamiento profiláctico, y en crisis agudas: experiencia en Perú
Authors: Calderón LLosa Oscar Manuel , Muñoz Campos Danny , Olivares Gómez Margarita
Published: April 2024

Antecedentes: El Angioedema Hereditario (AEH) se caracteriza por episodios de hinchazón a niveles cutáneo y submucoso, una crisis podría causar muerte por asfixia. Además, afecta la calidad de vida de las personas que la padecen. Existe una disparidad importante de medicamentos específicos para el AEH entre países, inclusive en nuestra misma región. En Perú donde no son viables estos tratamientos, se utiliza el Ácido Tranexámico (AT) para las Profilaxis de Largo y Corto Plazo (PLP / PCP), y para las crisis agudas de AEH.
Objetivo: Reportar la experiencia con el tratamiento de AT en tres tipos de pacientes con AEH, para que pueda ser usada como referencia en otros países en los que aún no se cuenta con medicamentos específicos para la enfermedad.
Reporte de caso: Paciente 1: Mujer de 49 años, AEH Tipo 1. Inició síntomas a los 12 años de edad. Diagnóstico definitivo a los 45 años. Actualmente, presenta crisis cada dos meses. Se le administran dosis de 2 g por IV de AT, cuando empieza crisis en cara, lengua y labios. Eventualmente ha necesitado entre 1 y 2 g por IV (después de cuatro horas), ella recibe PLP con AT (500 – 750 mg) cada 12 horas. Paciente 2: Mujer de 47 años, AEHnC1INH-FXII. Inició síntomas a los 19 años durante su primer embarazo. Diagnóstico definitivo a los 41 años. Ella mantiene PLP con AT (750 mg – 1,5 g) diariamente. Los ataques de vía respiratoria alta son tratados inmediatamente con AT cuando la crisis inicia, con dosis de 1 a 2 g por IV. Paciente 3: Mujer de 43 años, AEH-nC1INH-D. Estudio genético no detecta mutación en SERPING1, PLG1, ANGPT1, KNG1 y FXII. Inició síntomas a los 4 años. Diagnóstico definitivo a los 36 años. Al iniciar las crisis, se administra AT por VO, entre 500 a 750 mg/12 horas durante dos o tres días con aceptable respuesta y tolerancia a los episodios de AEH. Mientras las pacientes reciban dosis de mantenimiento de AT, entre 500 y 750 mg cada 8 o 12 horas, las crisis suelen ser de menor intensidad y se resuelven en menos días. 
Conclusiones: En nuestros pacientes con AEH, hemos utilizado AT hasta 4 g vía intravenosa en un intervalo de cuatro horas (2 g - 2 g); para el control de crisis agudas, cuando la reacción está cediendo, prescribimos la dosis de mantenimiento, 1 g/8 h con disminución progresiva de la dosis en los días siguientes. El tratamiento con ácido tranexámico ha sido de utilidad en nuestros pacientes con los distintos tipos de AEH. La mayoría de ellos utilizan altas dosis de AT para disminuir lentamente las crisis agudas de AEH. Se puede administrar vía oral o intravenosa. Es un medicamento que puede ser de ayuda en países donde no se tiene registro de tratamientos específicos para la enfermedad. Las dosis de AT han sido bien toleradas y con una respuesta aceptable en las crisis de estos pacientes con AEH.
Estudio inicial de captación e identificación de pólenes y hongos ambientales en Samborondón, Ecuador
Authors: Calderón LLosa Oscar Manuel , Cevallos Levicek Denisse , Ramón Germán , Barrionuevo Laura , Robles Karla , Tinoco Ivan , Chérrez Iván
Published: April 2024

Initial study of trap and identification of environmental pollens and fungi spores in Samborondon, Ecuador
Introduction: The identification of local aeroallergens in any geographical area is essential for the specific diagnosis and treatment of allergic diseases. Our objective was to identify and registry the most important aeroallergens trapped at the aerobiology station in the city of Samborondon, Ecuador.Material and methods:Pollen grains and fungal spore counts were performed according to the standardized technique with a Hirst-type collection equipment, Burkard spore trap for seven days, following the recommendations of the National Allergy Bureau (NAB) of the American Academy of Allergy Asthma and Immunology (AAAAI). The equipment was installed on the roof of the Universidad de Especialidades Espiritu Santo (UEES), 25 m above ground level, coordinates: 2°07 ́57 ́ ́S 79°52 ́06 ́ ́W, in the city of Samborondon. The sampling period was performed from November 2022 to April 2023.Results:We identified the following pollen families: Poaceae (258 grains/m3), Apocynaceae (Plumeria rubra pc) 214 grains/m3, Lamiaceae (180 grains/m3), Asteraceae - Ambrosía spp.- (60 grains/m3), Chenopodiacea (27 grains/m3), Myrtaceae (17 grains/m3), Pinaceae (11 grains/m3), Betulaceae (7 grains/m3).Also identified fungical spores: Fuzariella spp./Leptosphaeria spp. (1899/m3), Cladosporium spp. (1407/m3), Nigrospora spp. (1183/m3), Dreschlera/Helmintosporum spp. (329/m3), Alternaria spp. (98/m3), Pithomyces spp. (79/m3), Curvularia spp. (48/m3), Stemphylium spp. (46/m3).Conclusions:We reported the first study of aerobiology (capture and identification of environmental pollens and fungi) in the city of Samborondon. The inhabitants of this area are exposed to different aeroallergens with a predominance of Poaceaes pollen and Fuzzariella spp./Leptosphaeria spp. spores. The identified allergens should be part of the usual allergy studies. The results of this first preliminary study should be compared with information from the forthcoming years, which will help to identify variations in the concentration of seasonal aeroallergens, annual fluctuations, and extend the traps to other parts of the city.Key words: aerobiology, allergic rhinitis, allergic conjunctivitis, pollens.
Análisis de los perfiles electroforéticos de los extractos proteicos de las especies Manihot esculenta (Crantz,1975), Persea americana (Mill.,1768) y Actinidia deliciosa (A. Chevalier., 1984), y su asociación con el síndrome látexfruta para la búsqueda de alérgenos potenciales
Authors: Lagares Guzmán Alfredo , Juliana Jaspe  , Daibeth Domínguez  , Angela Muñoz  , Eduardo Egea
Published: April 2024

Objetivo: Determinar los perfiles electroforéticos de los extractos de Manihot esculenta, Actinidia deliciosa y Persea americana y su posible relación con el Síndrome de Látex – Fruta.
Métodos: Se prepararon extractos proteicos de M. esculenta, P. Americana y A. Deliciosa, a través de los procesos de macerado y extracción con solventes a partir muestras vegetales. En el caso del aguacate, se realizó una extracción previa por soxhlet, para eliminar la grasa. Los extractos se filtraron al vacío, se sometieron a diálisis y por último se liofilizaron. La separación de las proteínas en función del peso molecular se realizó mediante electroforesis SDS PAGE. Se compararon los perfiles electroforéticos obtenidos con las proteínas alergénicas previamente identificadas en el extracto de látex, con el fin de determinar una posible relación con el Síndrome de Látex-Fruta, en función del peso molecular.
Resultados: Los extractos de M. esculenta y P. americana mostraron una amplia gama de fracciones proteicas con pesos moleculares que varían desde 10 a 250 KD, encontrando que la región con mayor concentración de bandas se situó entre 20 y 89 KD, (60 y 65 %), respectivamente. Se obtuvo un perfil de 20 bandas para el extracto de M. esculenta (figura 1), con siete bandas que comparten pesos similares con los alérgenos del látex (Hev b 1, Hev b 2, Hev b3, Hev b 4, Hev b 5, Hev b 6.03, Hev b 8 y Hev b 10) (3-5). Para el extracto de P. americana, también se observaron 20 bandas (figura 2), siete de las cuales presentaron pesos aproximados a los alérgenos de Látex (Hev b 1, Hev b 2 Hev b 4 Hev b 6.01 Hev b 6.03 Hev b 8, Hev b 10 Hev b 11 Hev b 14). El extracto de Kiwi mostró dos bandas de 19,1 y 22,9 KD, con pesos cercanos a proteínas de látex (figura 3), (Hev b 3 y Hev b 6.01), y los alérgenos (Act d 2 y Act d 6), reportados en la literatura para esta fruta.
Conclusiones: Al analizar la relación existente entre las fracciones proteicas separadas y los alérgenos de los látex descritos en la literatura, se encontró una posible asociación del 35% para los extractos de M. esculenta y P. Americana, y del 10% para A. Deliciosa, siendo de gran relevancia la asociación encontrada con los alérgenos Hev b 4, Hev b 2, Hev 8 y Hev b 11, los cuales se encuentran implicados en el Síndrome de Látex-Fruto. Se lograron determinar los perfiles electroforéticos de los extractos elaborados y se compararon con los alérgenos del Látex. Está información genera un aporte para el desarrollo de nuevas investigaciones y avances en la estandarización de estos extractos a gran escala y para su uso futuro en pruebas diagnósticas.
Heterogeneidad de alelos HLA, en una muestra de pacientes con diagnóstico de artritis psoriásica en Colombia
Authors: Meneses-Toro Maria-Alejandra , Calixto Omar-Javier , Chacón Jaramillo Paula Andrea , Acevedo Godoy Mónica , Robayo Beltrán Luisa Constanza , Vera-Parra Camilo , Bello-Gualtero Juan-Manuel , Bautista-Molano Wilson , Noguera-Castro Verónica , Romero-Sanchez Consuelo
Published: April 2024

Background and objectives
Psoriatic arthritis (PsA), being part of the group of spondyloarthritis (SpA), is significantly influenced by the different subtypes of human leukocyte antigens (HLA). There is little data in Colombia and Latin America, but heterogeneity secondary to miscegenation is evident. It has been previously reported that HLA B27 in this region ranges between 5-71% for patients with SpA, and in Brazil, PsA has a frequency of 27.3% positivity. The objective is to describe the HLA allelic frequency in PsA and correlate it with demographic and clinical variables.
Methods
Retrospective study of adult patients with a diagnosis of PsA (n=23) and healthy controls (n=46), all with a request for HLA-A, B, C, DR. Typing was performed using HLA-PCR/SSO LifeCodes and analyzed on the LUMINEX IS100/200 xMAP® system. (Ethics/Code HMC2022-014).
Results
One hundred thirty-eight alleles were included from 69 individuals, 43.5% women, aged 44.5±16.5 years in patients with PsA, with a mean age of disease onset of 33.4±14 years. Only 9.5% had a high Body Mass Index and dyslipidemia was the most frequent comorbidity (34.8%), followed by high blood pressure (26.1%). 82% debuted with skin manifestation and once the joint disease was established, the predominance was peripheral (74%) due to arthritis/arthralgia in 74%, enthesitis in 30% and dactylitis in 13%. The allele frequencies were for HLA*A 2402 (13%), 3201 (13%) and 2427 (8.7%), for HLA*B 1402 (17.4%), 4002 (17.4%), 3801 (13%) and HLA*DR 0404 (17.4%), 0407 (13%). No HLA*B27 was identified and HLA*C0602 was only 2.2%. HLA A*0201 and DR*1301 were less frequent in controls versus PsA (p=0.024 and 0.029, respectively), while HLA*B1302 was frequent in PsA (p=0.035).
Conclusions
Curiously, there were no positive results for HLAB*27, which may be related to the population mix. HLA Cw6 is traditionally associated with psoriasis. However, its absence has been linked to nail disorders and PsA; consequently, in our study, it had a low frequency (2.2%). On the other hand, HLA*B1302 has been related to the disease and its early onset; in the healthy Colombian population, it has been described in 0.92%; in our group, it is found to be significant in patients without establishing a clinical association. Few previous studies report HLA results in PsA in Colombia.
Anafilaxia por leguminosas: reporte de un caso
Authors: Alzate-Pérez Leidy Johana , Aguirre Morales Natalia , Diez Zuluaga Libia Susana
Published: April 2024

ABSTRACT
Keywords:  Food Hypersensitivity,  Fabaceae,  Anaphylaxis
INTRODUCTION
Legumes belonging to the family Fabaceae of the order Fabales are a widely consumed source of protein.  IgE-mediated hypersensitivity reactions to legumes have been described, the most studied allergens being peanuts and soybeans. In the Mediterranean region and India, lentils, chickpeas and peas have been considered important allergens and legumes have been reported to represent the fifth most common cause of food allergy in children under 5 years of age in Spain. In Latin America, there are few reports of allergy to legumes other than peanuts, and these are especially in the paediatric population.
OBJECTIVE
To describe a case of IgE-mediated legume allergy in an adult female patient.
RESULTS
We describe the case of a 65-year-old female patient who reports a 20-year history of generalised urticaria, accompanied by angioedema and dyspnoea occurring immediately after consumption of lentils, beans, chickpeas, soya beans and cold meats, requiring admission to the emergency department for this cause. Tolerates peanuts.  She does not report anaphylaxis in any context other than those described. He has presented generalised pruritus with exposure to fumes from cooking beans.
Pathological history: Hypertension, type II diabetes mellitus, hypothyroidism.
Allergic: Anaphylaxis due to penicillin at the age of 30.
Other history: extensive local reaction to hymenoptera sting.
Prick test trophoallergens: soya 3 mm 
Prick to prick protein based on commercial soybean 7mm, chickpea 5mm, lentil 6mm and bean 7mm.
He was negative for wheat and peanut (Image 1) (Attached in separate file). 
It has normal tryptase report.
Indication was given for adequate adrenaline and strict avoidance of legumes, except peanuts.
 
CONCLUSIONS
Legume allergy is little known in our environment and mainly affects children.  Clinical manifestations include mild reactions and anaphylaxis. A high degree of cross-reactivity among legumes has been reported.  Lentils have cross-reactivity with chickpeas and beans. Peanut allergy may also be associated with allergy to lentils, chickpeas and peas, but is less frequently reported.
Determinación de poblaciones circulantes en sangre periférica de linfocitos T, reguladores CD4+ CD25+ CD127-, en niños asmáticos alérgicos
Authors: Reina Rivero Randy , Barrios Angulo Carlos E. , De Vivero María Mónica , Guzmán María Camila , Caballero Barboza Miguel Ángel , Acevedo Nathalie
Published: April 2024

Introduction: The type 2 immune response participates in the defense against parasitic infections, but in the context of asthma and allergies, this response can react disproportionately to environmental allergens, triggering inflammation and airway hyperreactivity. Regulatory T cells (Tregs) play a fundamental role in modulating and controlling the inflammatory response; thereby, a decrease or dysfunction of Tregs could result in increased sensitization to allergens, aggravating asthma and allergies. Evaluations of Tregs usually include intracellular stains for Foxp3, but a new immunophenotyping panel can detect Tregs by staining with CD25 and CD127.
Objective: To carry out a preliminary analysis on the Treg lymphocyte counts present in the peripheral blood of allergic asthmatic children from the city of Cartagena (Colombia) compared to healthy controls.
Methodology: We compared cytometry counts of 10 asthmatic patients (age 7-16 years) and 7 healthy controls (6-12 years) recruited in the city of Cartagena. Peripheral blood samples were stained using Cytek’s 14-color cFluor Immunoprofiling kit (Cytek® cFluor® Immunoprofiling Kit 14 Color RUO kit) and analyzed on a Northern Lights™ spectral cytometer (Cytek® Biosciences, Fremont, CA, USA) to read 50,000 events per sample. The data obtained were analyzed in SpectroFlo® and FlowJo. The study was approved by the ethics committee of the University of Cartagena (SGR, Grant BPIN2020000100405).
Results: The frequency of CD3+ CD4+ CD25+ CD127- Tregs was 11% of all CD4+ T cells, with a range of minimum 8.1% and maximum 17.7%. There was no significant difference in the proportion of Tregs between allergic asthmatic patients and healthy controls (P = 0.2).
Conclusions: With this preliminary sample size, no significant differences were found in the Treg lymphocyte population between allergic asthmatic patients and healthy controls. The 14-color multiplexed panel is a useful tool not only to count CD3+ and CD4+ populations but also to obtain the percentage of regulatory T cells using cell surface markers.
Funding: This study was funded by the SGR, project BPIN2020000100405 and the University of Cartagena.
Declaration of conflict of interest: The authors declare that they have no conflicts of interest in relation to this work.
Arquitetura, urbanismo e paisagismo: contribuições conceituais e projetuais - Volume 3
Authors: Camara Andreia Jane Leandro , Marques Andreia Mesquita Santos , Morais Cintia Maria de Aguiar , Pereira Barriga Feitosa Nairama
Published: April 2024

O livro apresenta vários estudos que incentiva a pesquisa na área da Arquitetura e Urbanismo e corrobora com a necessidade crescente de projetar de forma mais abrangente. A composição do livro é através de capítulos que abordam temas diversos. Assumimos que ainda temos muito caminho a percorrer, no âmbito da atuação profissional no que tange a compreensão, investigação e contextualização de projetos arquitetônicos e urbanísticos.
Effects of Therapy Dogs on Trauma-Affected Students: A Retrospective Study on Survivors of the Marjory Stoneman Douglas High School Shooting
Authors: Shapiro Annalee , Gillen Martie , Dixon Brittney , Fogarty Kate
Published: April 2024

School shootings are traumatic events that can lead to anxiety, depression, and post-traumatic stress disorder among students who experience these events. It is important to find effective strategies to help students cope with their return to school, as well as their anxiety and stress levels while on campus. There exists a gap in the literature on the effects of therapy dogs on students who have witnessed a school shooting. This current study used a retrospective mixed-methods survey that was sent to recent graduates of Marjory Stoneman Douglas High School (located in Parkland, Florida) who witnessed the February 2018 shooting. Data were collected to assess how the therapy dogs affected students' willingness to return to school and their stress/anxiety levels while on campus. Identified themes indicated that the therapy dogs helped with anxiety levels, stress levels, and overall moods of Marjory Stoneman Douglas High School students. These findings provide important implications for community leaders and school administrators who want to promote healing and well-being in a community that has experienced violence.
Teachers' Perceptions Towards Decision-Making Processes: A Case Study of Secondary Schools in Rwanda
Authors: Musengamana Irene , Rhaman Shaoan Md Mirajur , Namanyane Tebatso Moses , Chineta Okoye Maureen , McNamara Patricia Mannix
Published: April 2024

The significance of participatory decision-making in educational institutions is widely acknowledged as essential in school management and administration. This study aimed to determine how involved teachers are in making decisions in their schools and what role they think they play in shaping different parts of school policies and procedures. It also looked at their perspectives on how decisions made by others are carried out in schools. Semi-structured interviews with 10 secondary school teachers focused on teachers' role in decision-making related to their routine school tasks, strategic decision-making, participatory role in making school decisions, and their willingness to participate in decision-making. This study showed that teachers' low participation is attributed to their shared desire to be involved in school management and administration-related decisions. Teachers expressed that participatory school-based decision-making can promote collaboration and collectivism among the school staff, and it plays a significant role in shaping their work satisfaction and motivation. By gaining insights into teachers' perspectives, this study aims to contribute to the broader understanding of participatory school decision-making in the Rwandan secondary education system and communicate potential improvements for fostering a more collaborative and inclusive educational environment.
“Like a Sacrifice Ascending from the Flames”: Hadar Goldin’s Mesilat Yesharim in Israeli Religious Nationalist Thought
Authors: Stern Nehemia
Published: April 2024

Abstract: This article tracks how Mesilat Yesharim , an eighteenth-century devotional work of pietistic asceticism, has been transformed by Jewish religious Zionists in Israel and the West Bank into an experience of military and civic duty. It specifically focuses on a contemporary popular commentary on the text authored by Lieutenant Hadar Goldin, a religious Zionist casualty of Israel’s 2014 conflict with the Hamas-controlled Gaza Strip. It argues that the study and interpretation of the Mesilat Yesharim by religious Zionists in Israel ultimately functions as a sacred textual medium through which these communities are able to better navigate between the competing obligations that characterize their social, political, and theological positions within Israeli society. When seen through this lens, Mesilat Yesharim serves as a sacred literary vehicle through which young men and women, facing years of national service, work through some of the conflicting loyalties of their own moral worlds.
Primera detección en Argentina y nuevos registros en Chile de Boisea trivittata (Say, 1825) (Heteroptera: Rhopalidae: Serinethinae)
Authors: Faúndez Eduardo I. , Carpintero Diego L. , Leiva Fernando
Published: April 2024

Se reporta por primera vez la presencia de la chinche del arce o chinche del maple Boisea trivittata en Argentina, con ejemplares provenientes de Godoy Cruz, Mendoza. Adicionalmente se entregan los primeros registros en Chile para la Región del Maule correspondientes a las localidades de Curicó y Romeral, siendo hasta ahora los más australes en  Sudamérica.
Evaluating the impact of digital technology on youth leadership development in the USA
Authors: Olateju Temitope Akintayo  , Chima Abimbola Eden  , Nneamaka Chisom Onyebuchi
Published: April 2024

Digital technology has become an integral part of modern society, influencing various aspects of daily life, including education and leadership development. This study aims to evaluate the impact of digital technology on youth leadership development in the USA. The research explores how digital technology, such as social media, online platforms, and digital communication tools, influences the development of leadership skills and qualities among young people. The study employs a mixed-methods approach, combining quantitative surveys and qualitative interviews to gather data from a diverse sample of youth leaders across the USA. Quantitative surveys are used to assess the extent to which digital technology is used in leadership development programs and its perceived impact on leadership skills. Qualitative interviews provide deeper insights into how digital technology influences the development of leadership qualities, such as communication, collaboration, and problem-solving skills. Preliminary findings suggest that digital technology plays a significant role in youth leadership development, offering new opportunities for learning and growth. Social media platforms, in particular, are identified as valuable tools for connecting with peers, sharing ideas, and mobilizing support for various causes. However, the study also highlights challenges associated with the use of digital technology, such as the risk of information overload and the potential for online harassment and bullying. The study concludes by emphasizing the need for educators, policymakers, and youth organizations to recognize the potential of digital technology in enhancing leadership development while addressing its challenges. Recommendations are provided for integrating digital technology into leadership development programs effectively, including the importance of digital literacy education and the need for policies that promote safe and responsible digital practices among young leaders. Overall, this study contributes to the growing body of literature on the impact of digital technology on youth development, providing valuable insights for practitioners and policymakers seeking to harness the power of digital technology for youth leadership development in the USA.
The prevalence, consequences, and outcome of perinatal asphyxia in term and late preterm live-born neonatesA A case-control study from Iran
Authors: Ziba Mosayebi  , Sedigheh Hantoushzadeh  , Amir Nadaf  , Atousa Moeinafshar  , Mohamad Reza Zarkesh  , Mamak Shariat  , Hasti Charousaei  , Roksana Moeini
Published: April 2024

Background: Despite several investigations reporting the prevalence of asphyxia in developed and developing countries, very few studies from Iran have demonstrated the rate of neonatal asphyxia and its affecting factors. Objectives: This study aimed to determine the prevalence of asphyxia, its consequences, and neonatal outcomes among Iranian term and late preterm live-born neonates. Methods: A case-control study was conducted in three hospitals; Vali-e-Asr, Yas, and Ziaean from April 2019 to March 2020. The case group included neonates with a history of perinatal asphyxia. Twice gestational age-matched subjects without such a history also entered the study as the control group. All maternal and neonatal data were collected from participants’ medical records. Determining the prevalence of neonatal asphyxia was the primary outcome of the present study. Results: Totally 48 subjects as the case and control groups were included and 16 asphyxiated cases were observed equal to 3.3 per 1000 live-born neonates. Concerning the type of delivery, cesarean section in the control group and vaginal delivery in the case group were the most frequent types of delivery (p=0.041). Comparing neonatal variables, the results showed a significant difference regarding the groups’ genders (p=0.036). Apgar scores in the case group were also significantly lower than the control group (p=0.0001). More cases also required PPV compared to the controls (12 vs. 0; p=0.0001). Hypoxic-ischemic encephalopathy (HIE) grade 1 was also significantly more frequent in the case group than the controls (p=0.0001). The means of pH and base excess in the case group were significantly lower than the control group (p=0.0001). Conclusion: The results showed the prevalence rate of asphyxia among term and late preterm participants was 3.3 cases per 1000 live-born neonates. Apgar scores<5 accompanied with metabolic acidosis, HIE, and requirement of PPV could be predictive variables for perinatal asphyxia. Observing such clinical risk factors may indicate the need of early diagnosis and timely interventions to improve neonatal outcomes.
Epidemiological study of the occurrence of measles in children aged 0-15 years in the Banalia Health Zone (DR Congo) during 2022
Authors: Jacques Alaima Manda  , Lucien Lisangi Tuli  , Héritier Kuda Mbuya  , Raymond Assani Ramazani
Published: April 2024

Introduction: In 2021, the Banalia Health Zone experienced two measles epidemics with a vaccine completeness rate of 69% according to data provided by the Tshopo Provincial Health Division. The aim of the study was to list the epidemiological characteristics of measles cases in the Banalia Health Zone, to determine the incidence of measles in children aged 0-15 years, and to analyze the vaccination status of children with measles. Methodology: This was a retrospective descriptive study, based on the acquisition of data from the medical records of the targeted children or from data registers at the time of submission. A total of 3,968 children with measles were selected from the various health centers and areas of the Banalia Health Zone. Results: We observed that 64.6% of the subjects in the study were aged between 0 and 5 years; 40.77% of measles cases were recorded in September 2022. The measles vaccination rate was 39.19% and the case fatality rate was 2.8%. The Panga 2 axis had the highest number of measles cases, with a prevalence rate of 29.03%. Conclusion: Measles is a major cause of morbidity and mortality in the Banalia Health Zone. The age group most affected is 0-5 years. Vaccination and surveillance systems need to be strengthened to reduce the growing risk posed by measles.
Exploring the impact of AI-driven solutions on cybersecurity adoption in small and medium enterprises
Authors: Geeta Sandeep Nadella  , Hari Gonaygunta  , Deepak Kumar  , Priyanka Pramod Pawar
Published: April 2024

This study delves into the intricate dynamics of cybersecurity adoption within small and medium enterprises (SMEs), with a specific focus on the transformative potential of AI-driven solutions from a machine learning perspective. Leveraging a rich and diverse dataset of real-world cybersecurity incidents tailored to the SME context, the research meticulously investigates the efficacy of three prominent machine learning models: logistic regression, random forest, and gradient boost classifiers. Through a comprehensive evaluation using a suite of performance metrics, including accuracy, precision, recall, and F1 scores, the study scrutinizes the predictive capabilities of these models in forecasting and categorizing cyber threats encountered by SMEs. The findings unveil nuanced insights into the multifaceted challenges and opportunities inherent in the cybersecurity landscape of SMEs, shedding light on the complex interplay between AI-driven solutions and evolving cyber threats. While the analysis reveals commendable performance across the models, it also uncovers inherent limitations in accurately discerning and categorizing specific types of attacks. These findings underscore the critical need for ongoing refinement and optimization of AI-driven cybersecurity solutions, necessitating a continuous, iterative process informed by real-world data and adaptive learning mechanisms. By harnessing the strengths of machine learning and embracing a proactive stance towards cybersecurity, SMEs can fortify their defense mechanisms and safeguard their digital assets in the increasingly volatile and interconnected digital ecosystem.
Analysis of measurement of the working environment of machine noise in the production area in packaging factory
Authors: Salsabila hanna  , Noeroel Widajati
Published: April 2024

Noise is an unwanted and disturbing sound that can damage comfort, work peace, hearing, blood pressure, heart rate and muscle tension. The threshold limit value (TLV) for noise in the company is 85 dB with 8 working hours of exposure. This research uses a quantitative observational method by directly observing machine noise and the noise received by workers. The way to measure noise is by using a calibrated sound level meter. The results of this research are threshold values, namely 85.7 dB and 90.5 dB. The noise is above TLV due to the many machines in one room and the additional equipment, namely blowers, on each table. However, in this situation, workers are obedient in using earplugs. Noise can cause disruption to hearing organs, workers' psychological conditions, and decreased worker productivity. This research shows that the noise condition of PT X's production area exceeds the threshold value set in PERMENAKER 5 of 2018. This research further recommends conducting safety patrols to ensure workers use earpugs or earmuffs and the use of earplugs or earmuffs correctly.