bluuebunny/crossref_metadata_2025 huggingface dataset:
Sufistic Self-healing: The Intersection of Sufism and Psychology
Authors: Hidayati Laily , Fatimah Siti
Published: July 2024

Humans always desire to know themselves, know the world around them, and know their place in the world. This search has taken humanity from religious dogmas to philosophical discourse and the empirical sciences. Although human civilization has progressed in various alternatives for understanding the self about nature, the answers remain elusive. Spirituality, whether related to a particular religion or another, has been practiced for a long time and is claimed to provide answers to “unresolved doubts” (S. Haque Nizamie, et al, 2013). In recent years, there has been an increase in interest in spirituality, and advances in neuroscience have provided an opening to understand it from a more scientific viewpoint and place it in the proper perspective. In various cultures, spirituality is an important part of the belief system of the majority of society. This affects mental well-being and understanding of mental illness in terms of etiology, meaning, and self-healing modalities. It seems important for mental health professionals to be aware of how spirituality influences the mental well-being of individuals in both health and illness. This paper will outline the basic foundations of Sufism, how Sufism affects the mental well-being of individuals associated with it, and its relationship with psychology.
The Evolution of Tariqah in Sufism
Authors: Falquinzani Alzena Mahesadewi , Rahma Bella Putri , Amin Maulida Izzatul
Published: July 2024

In the modern world, tariqah is something that is very much needed by Muslims. Because with tarekat, humans have means and ways to return and recognize the nature of God in depth. In the history of its development, Tarekat not only focuses on Sufism or the teachings of its teachers (Mursyid), but also follows political activities. For example, the Tijaniyah Order is known as a political movement that opposed French colonization in North Africa. This research uses a qualitative method with a historical approach that refers to books, journals, with the concept of library research. The purpose of this tarekat in general is to strengthen the faith of a servant to his Lord. The results show that a tariqah can expand in various parts of Islam in large numbers. Tariqah in Sufism have developed widely. Some of which are such as Qadiriyah, Naqsyabandiyah, and Shadziliyah and others.
Kemandirian Ekonomi Melalui Pendekatan Tasawuf: Implementasi Filosofi Sirih Jamaah Tarekat Shiddiqiyah
Authors: Rahman Hendra Yulia , Zahro Ahmad , Ritonga Iskandar , Abza M Thohar Al
Published: July 2024

Artikel ini mengeksplorasi konsep kemandirian ekonomi dengan memanfaatkan pendekatan Tasawuf, khususnya melalui filosofi Sirih dalam Jamaah Tarekat Shiddiqiyah. Konsep kemandirian ekonomi menjadi semakin penting dalam konteks pembangunan ekonomi yang berkelanjutan dan inklusif. Penelitian ini kualitatif dengan pendekatan deskriptif analisis. Dalam penelusuran literatur primer dan sekunder, kami menyoroti nilai-nilai spiritual dan praktik ekonomi yang diterapkan dalam Jamaah Tarekat Shiddiqiyah, sebuah tarekat sufi yang menekankan kemandirian ekonomi terhadap jamaahnya. Hasil penelitian menunjukkan bahwa filosofi Sirih dalam Jamaah Tarekat Shiddiqiyah menjadi landasan penting dalam membangun kemandirian ekonomi. Praktik-praktik ekonomi seperti pertanian, perkebunan, kerajinan lokal, perhotelan, industri air mineral dan pabrik rokok menjadi bagian integral dari upaya mereka untuk mencapai kemandirian ekonomi. Dalam konteks ini, nilai-nilai spiritual seperti kesederhanaan, keadilan, dan ketekunan menjadi kunci dalam mengembangkan sistem ekonomi yang berkelanjutan dan inklusif. Artikel ini berkontribusi pada pemahaman tentang hubungan antara spiritualitas dan ekonomi, serta menawarkan perspektif baru dalam memahami kemandirian ekonomi. Implikasi praktis dan arah penelitian masa depan juga dibahas untuk meningkatkan pemahaman tentang konsep kemandirian ekonomi dalam konteks Tasawuf, khususnya dalam Jamaah Tarekat Shiddiqiyah.
A Semantic Analysis of the Relationship between Fitrah and Education
Authors: Ihsan Nur Hadi , Indallah Sayyid Muhammad , Shalahudin Henri
Published: July 2024

This article is a semantic analysis of the sentence fitrah in the Qur'an. As far as the author reads, the word fitrah is found twenty times with various derivations. The word fitrah has at least the meaning of religion, the command to religion, the creator, and disaster. This article aims to explain the meaning of the sentence fitrah in the Qur'an according to Islamic scholars and thinkers so as to create a complete concept. In analyzing this text, the author uses a descriptive-analytical method to explain the opinions of the scholars; from the etymological meaning of the word so that it becomes a whole concept. The results of this study found that there are at least three important points. First, human nature is religion, namely Islam. Second, human nature is to be a servant and caliph in the world. Third, human nature is the essence of a person; which if done will achieve the purpose for which humans were created or benefit; but if denied will only produce damage or madharat.
Eksistensi Penafsiran Al-Qur’an Perspektif Muhammad ‘Ajaj Al-Khatib dan Pengaplikasiannya
Authors: Anam Masrul
Published: July 2024

An interpretation of the Qur'an will be continue to development, because each interpreter has a different understanding and intelligence needs to be standardization will be continues to exist. the criteria identify for correct interpretation. Interesting from Muhammad Ajaj al-Khatib is a hadith expert but is able to formulate the existence of an interpretation. This research found that there are six criteria to existence of interpretation,
Competitiveness as a key factor in the financial stability of an organization
Authors: Zavalishina Alena , Turgaeva Aksana
Published: July 2024

In this publication, the author pays special attention to the problem of ensuring the competitiveness of the organization. He emphasizes that competition is fundamental in a market economy and emphasizes that successful organizations are those that can withstand both internal and external competition. The author believes that the competitiveness of an organization presupposes effective economic interaction with consumers, suppliers and competitors. The article examines the main components of competitiveness and proposes a classification of criteria for assessing the competitiveness of products. According to the author, the group criterion is a complex indicator that includes various characteristics that determine the competitiveness of a product from different points of view. In addition, the article notes that competitiveness in the domestic market differs from competitiveness in the foreign market due to government influence on the former. When assessing an organization's competitive position in the market, it is important to analyze its strengths and weaknesses, as well as the factors influencing consumer perception. The work provides various classifications for determining the competitiveness of an organization, including both external and internal factors. The author argues that to increase the competitiveness of an organization it is necessary to have primary competitive advantages. One of these benefits can be product differentiation, which allows you to stand out in the market and attract more customers. Another important factor is providing superior value, that is, offering products or services at better prices than competitors. It is noted that these factors not only contribute to increasing the level of competitiveness of the organization but can also become an obstacle. Achieving and maintaining competitiveness requires a skillful balance between product differentiation and superior value, taking into account both their positive and negative aspects
Optimization of Mycelial Growth Parameters in Lion's Mane Edible Medicinal Mushroom Hericium erinaceus (Agaricomycetes) by Supplementation of Growth Hormones
Authors: Diskit Stanzin , Gupta Sachin , Gupta Moni , Kour Pavleen , Devi Laxmi , Singh Ranbir
Published: July 2024

The present study was carried out to optimize the strain and evaluate the effect of amendment of growth media with different hormone concentrations for enhancing mycelium growth of lion's mane mushroom Hericium erinaceus under in vitro conditions. Among the five strains of H. erinaceus, He-04 strain showed maximum average GR (GRavr) of 4.78 mm d-1. Five different media, potato dextrose agar (PDA), malt extract agar, sawdust extract agar, wheat straw extract agar, and rice straw extract agar, amended with four concentrations (10, 20, 30, and 40 ppm) of gibberellic acid, kinetin, and indole acetic acid, were evaluated for promotion of mycelial growth of H. erinaceus. PDA was observed to be the best media promoting the mycelial growth of H. erinaceus. The highest mycelial GRavr 8.47 mm d-1 was observed in PDA amended with indole acetic acid (10 ppm) followed by gibberellic acid and kinetin (30 ppm) decreasing mycelial GRav to 8.15 and 7.75mm d-1, respectively. Temperature of 25°C and pH 7.0 was found to be the best for mycelium growth of H. erinaceus.
RELATIONSHIP BETWEEN ELECTROCARDIOGRAPHY AND ELECTROLYTES BEFORE AND AFTER DIALYSIS IN HEMODIALYSIS PATIENTS
Authors: Karahisar Şirali Semahat
Published: July 2024

Background: Cardiovascular events are the most important cause of mortality in hemodialysis patients. Rapid volume changes and electrolyte shifts during dialysis lead to arrhythmias.
Objective: We aimed to determine whether there is a relationship between electrocardiographic (ECG) wave and interval changes and electrolyte levels before and after hemodialysis in dialysis patients.
Materials and Method: A total of 112 patients undergoing hemodialysis three times a week for four hours for more than six months were included in the study. Before and after hemodialysis, 12-lead ECG, weight, arterial blood pressure, hemogram, biochemistry, and demographic data were recorded. Waves and intervals were calculated from the 12-lead ECG taken before and immediately after dialysis, and the relationship with serum electrolyte levels was evaluated. P
Reverse Shoulder Arthroplasty in the Treatment of Cuff Tear Arthropathy: Systematic Review
Authors: Aşcı Murat
Published: July 2024

Purpose: In our study, we aimed to examine the results and complications of reverse shoulder prosthesis (RSA) applied after rotator cuff tear arthropathy (CTA) in the light of the current literature.
Methods: The literature search was conducted simultaneously on 1 April 2024 in the Medline, Cochrane, EMBASE, Google Scholar and Ovid databases using the ''reverse total shoulder arthroplasty'', ''reverse total shoulder prosthesis'', ''cuff tear arthropathy'', ''outcomes'' and ''complications'' keywords. Only clinical review published in English in peer-reviewed journals was evaluated. The comparison between preoperative and postoperative clinical scores, as well as range of motion (ROM), was performed using the Wilcoxon–Mann–Whitney test. P values lower than 0.05 were considered statistically significant.
Results: 12 articles were included in our study. When comparing the results of the pre- and postoperative examinations, a statistically significant improvement in the range of motion and the functional score was found. It was found that various complications occurred in 21.1% of patients. The most common complication is scapular notching, which occurred in 13.8% of patients. Revision surgery was required in 1.57% of patients. The most common cause of revision was a periprosthetic joint infection.
Conclusion: In CTA patients, RSA can achieve both freedom from pain in the shoulder joint and an increase in function. Despite positive results, complications of varying degrees of severity can occur in around one fifth of patients. The lack of Level I studies limits a true understanding of the possibilities and limitations of RSA in the treatment of CTA patients.
Saberes ancestrales. Uso de las plantas medicinales del cantón Cuenca
Authors:   Universidad Politécnica Salesiana (Ecuador),   Universidad Politécnica Salesiana (Ecuador)
Published: July 2024

Saberes ancestrales hace un recorrido desde el origen de la medicina herbal a nivel mundial hasta las características propias de la geografía ecuatoriana y, en particular, de la rural Cuenca de los Andes. En sus parroquias distantes y cercanas, se encontró una variedad de plantas medicinales nativas, así como plantas introducidas adaptadas al clima de las montañas, valles y micro-cuencas hidrográficas. La investigación recoge también el conocimiento de los taitas y mamas de las comunidades andinas, cuya práctica de la medicina milenaria es digna de rescatar y replicar para el presente y el futuro. Les invitamos a hacer un recorrido a través de estas páginas, donde confluyen ciencia, salud y bienestar.
Capítulo IIIPlantas medicinales en las parroquias:Baños, Molleturo, Chaucha, Cumbe, San Joaquín, Victoria del Portete y Sayausí
Authors: Orellana Robles José ,   Universidad Politécnica Salesiana (Ecuador), Soliz Panamá John , Zea Cobos Geovanna ,   Universidad Politécnica Salesiana (Ecuador),   Universidad Politécnica Salesiana (Ecuador)
Published: July 2024

El presente trabajo experimental está enfocado en las parroquias Baños, Molleturo, Chaucha, Cumbe, San Joaquín, Victoria del Portete y Sayausí, con el propósito de realizar una guía etnobotánica. Se planificó una serie de actividades con el objetivo de recopilar información. Las encuestas y las entrevistas permitieron conseguir 51 especies de plantas en los diferentes recorridos etnobotánicos realizados con la ayuda de personas de cada localidad visitada. Se realizó una evaluación en cada parroquia, en las cuales se pudo determinar que la población femenina posee un mayor conocimiento sobre medicina alternativa, las mujeres se encargan de la recolección, mantención y aplicación de estos conocimientos ancestrales. También cabe destacar la pérdida masiva de la medicina ancestral, sobre todo en personas jóvenes, debido a la poca práctica y conocimiento sobre plantas medicinales. Asimismo, se determinó que las plantas más utilizadas y comunes son manzanilla, toronjil, menta y pena-pena. Posterior a esto se organizaron salidas de campo con el objetivo de conseguir un ejemplar de cada planta recopilada, siendo un total de 51 plantas consideradas y fotografiadas.
Sensitivity and specificity of International Classification of Diseases algorithms (ICD-9 and ICD-10) used to identify opioid-related overdose cases: A systematic review and an example of estimation using Bayesian latent class models in the absence of gold standards
Authors: Mbutiwi Fiston Ikwa Ndol , Yapo Ayekoe Patrick Junior , Toirambe Serge Esako , Rees Erin , Plouffe Rebecca , Carabin Hélène
Published: July 2024

Objectives

This study aimed to summarize validity estimates of International Classification of Diseases (ICD) codes in identifying opioid overdose (OOD) among patient data from emergency rooms, emergency medical services, inpatient, outpatient, administrative, medical claims, and mortality, and estimate the sensitivity and specificity of the algorithms in the absence of a perfect reference standard.

Methods

We systematically reviewed studies published before December 8, 2023, and identified with Medline and Embase. Studies reporting sufficient details to recreate a 2 × 2 table comparing the ICD algorithms to a reference standard in diagnosing OOD-related events were included. We used Bayesian latent class models (BLCM) to estimate the posterior sensitivity and specificity distributions of five ICD-10 algorithms and of the imperfect coroner’s report review (CRR) in detecting prescription opioid–related deaths (POD) using one included study.

Results

Of a total of 1990 studies reviewed, three were included. The reported sensitivity estimates of ICD algorithms for OOD were low (range from 25.0% to 56.8%) for ICD-9 in diagnosing non-fatal OOD-related events and moderate (72% to 89%) for ICD-10 in diagnosing POD. The last included study used ICD-9 for non-fatal and fatal and ICD-10 for fatal OOD-related events and showed high sensitivity (i.e. above 97%). The specificity estimates of ICD algorithms were good to excellent in the three included studies. The misclassification-adjusted ICD-10 algorithm sensitivity estimates for POD from BLCM were consistently higher than reported sensitivity estimates that assumed CRR was perfect.

Conclusion

Evidence on the performance of ICD algorithms in detecting OOD events is scarce, and the absence of bias correction for imperfect tests leads to an underestimation of the sensitivity of ICD code estimates.
Stress-Strain Characteristics and Electrical Conductivity of Niobium Nanopowder modified Silicon Bronze
Authors: Kingsley C Nnakwo , Jeremiah L Chukwuneke , Paul C Okolie , Chika O Ujah , Maxwell C Anukwonke
Published: July 2024

Understanding the response of materials to various loads is crucial for fabricating resilient components capable of withstanding anticipated stresses. This experimental study addresses the limited information on the tensile behavior of silicon bronze by investigating the stress-strain characteristics of Cu-4wt%Si alloys modified with niobium nanopowder. The surface morphology of the fabricated alloys was analyzed using a Scanning Electron Microscope (SEM). SEM analysis of the Cu-4wt%Si alloy revealed columnar grains sparsely distributed in the copper matrix, contributing to low strain-to-fracture behavior. Doping the alloy with niobium nanopowder resulted in notable grain modification, increased grain boundary density, and improved grain distribution, correlating with higher strain-to-fracture values. Notably, the Cu-4wt%Si-1.1wt%Nb alloy exhibited significant changes in percentage elongation, ultimate tensile strength, yield strength, fracture strength, and tensile toughness. Furthermore, niobium nanopowder additions increase the hardness and electrical conductivity values, peaking at 305 HV and 54.9 %IACS with 1.1 wt% Nb.
L’individuazione e il trattamento precoce dello scompenso cardiaco da cardiotossicità
Authors: Canale Maria Laura
Published: July 2024

Lo scompenso cardiaco rappresenta una tra le più frequenti tossicità cardiovascolari causate dai trattamenti oncologici, particolarmente rilevante in caso di trattamento con antracicline nel carcinoma mammario e nei linfomi e della terapia anti-HER2 nelle neoplasie mammarie. Oltre alle problematiche direttamente correlate allo scompenso per se, la sua insorgenza complica e spesso impedisce la prosecuzione di trattamenti fondamentali spesso con finalità curativa. Da ciò consegue che la sua precoce individuazione e l’impostazione di un trattamento specifico da parte del cardiologo/cardioncologo ha la duplice valenza di migliorare la funzione cardiaca e quindi i sintomi e permettere di valutare la prosecuzione del trattamento oncologico. La stretta collaborazione tra cardiologo e oncologo/ematologo è fondamentale per una corretta ed efficace gestione di questa tossicità.
Psychological Driver Sensitivity in Lattice Hydrodynamic Traffic Model under Passing Behaviour
Authors: Mehra Meenakshi ,   Department of Mathematics, Maharshi Dayanand University, Rohtak, 124001, Haryana, India, Yadav Sunita , Redhu Poonam
Published: July 2024

Objectives: In order to control and manage the traffic flow in contexts of congestion, real-time highway traffic flow models play a significant role in intelligent transportation system. The objective of our investigation is to examine the effect of psychological driver sensitivity (PDS) when coupled with passing behaviour. Methods: In this study, we developed the lattice hydrodynamic (LH) model which is a good and simple representation for solving traffic problems. Its variants have been valuable tools in traffic research and also contributed to our understanding of traffic phenomena and the development of traffic management strategies. The effect of the proposed LH model with the factor PDS and passing is examined through linear stability analysis. Employing nonlinear stability analysis, we are able to establish the permissible range of PDS values in conjunction with a passing constant, ensuring the existence of kink soliton solution for the mKdV equation. Findings: To validate our theoretical findings, we conducted numerical simulation, conclusively demonstrating that the integration of PDS with passing in the proposed model, can efficiently mitigate traffic congestion. When we fix the passing coefficient and vary the PDS coefficient, we identify the enlargement of stable region with small PDS values. Similarly, by fixing the PDS coefficient varying passing coefficient reveals the enlargement of stable region with small passing values. Novelty: Results displayed that the stability performance of the proposed model is higher than the existing LH model with passing and found that our proposed model performs better than existing models to alleviate traffic congestion and improve traffic flow. Keywords: Traffic flow, Lattice hydrodynamic model (LHM), Psychological driver sensitivity (PDS), Passing effect, Stability
Evaluation of Haemostatic Potential and HPTLC Fingerprinting of Annona squamosa Linn. Bark Extract
Authors: Bhagwat Janhavi Ameeya ,   Assistant Professor, Department of Zoology, Ramniranjan Jhunjhunwala College of Arts, Science and Commerce (Autonomous), Ghatkopar, Mumbai, 400086, Maharashtra, India
Published: July 2024

Objectives: The present work focuses on exploring and evaluating the hemostatic property of Annona squamosa Linn. bark. Being a renewable resource, it has the potential to contribute to the hemostatic agent. Hemostatic efficacy of the cold and hot bark extract at different concentrations of 10, 50, 100 & 250 mg/ml of saline were evaluated using whole blood clotting, platelet aggregation test, prothrombin time CAMAG HPTLC system. The hemostatic efficacy. At 250 mg/ml saline, both the extracts showed excellent hemostatic efficacy by clotting blood in 1.2 s and 3 s, respectively. The prothrombin time of cold and hot were 5 s and 5.1 s which were less than that of Liquiplastin partial prothrombin time which was Liquicelin E (13.85 s). Annona squamosa Linn. to be used as a topical hemostatic agent. Saponins, which are known to be antihemorrhagic, were detected by HPTLC. hemostatic efficacy of Annona squamosa Linn. bark was evaluated, which can contribute to the development of a fast-acting, cost-effective, easy-to-use, and sustainable topical hemostat. Keywords: Annona squamosa Linn, Hemostatic activity, Prothrombin time, Activated partial thromboplastin time, HPTLC fingerprint
E-Gel Protocol EFGL v1
Authors: GeneticsLab EagleFish
Published: July 2024

The purpose of this protocol is to determine successful polymerase chain reaction (PCR) amplification. This is achieved by preparing PCR sample and ladder droplets, preparing the E-Gel‱ Power Snap, depositing all samples into appropriate lanes on an E-gel of the E-gel, and viewing the results on the E-Gel‱ Power Snap Camera. This will result in an image of a gel, that has a ladder that can be compared to the desired PCR samples.
Human Knee Tissue Procurement, Resection and Multimodal Analyses v1
Authors: Olmer Merissa , not provided hswahn , Lotz Martin
Published: July 2024

This protocol describes the procurement of entire human knee joints, resection of joint tissues and allocation for multimodal analyses. The protocol is focused on entire knees that are recovered by Organ Procurement Organizations and parts of the protocol are also applicable for human joint tissues that are removed during surgery on the knee or other joints. For entire knees, samples of all joint tissues are resected to allow analysis of ‘the knee as an organ’.
El modelo médico hegemónico y su impacto en la atención a víctimas de violencia sexual: la noción de revictimización en las narrativas de médicos y médicas
Authors:   Universidad CES, Moreno-Realphe Sandra-Patricia
Published: July 2024

Objetivo: Reconocer los significados y las prácticas de médicas y médicos acerca de la revictimización en su encuentro con víctimas de violencia sexual en urgencias hospitalarias. Metodología: Estudio que tuvo como referente un paradigma crítico social posmoderno, mediante una investigación cualitativa con enfoque etnográfico y estudio de caso colectivo, llevado a cabo entre febrero y diciembre de 2021. Participaron médicas y médicos con experiencia en atención a víctimas de violencia sexual en servicios de urgencias y referentes (psicóloga y enfermera) de dicha atención en dos hospitales universitarios de la ciudad de Medellín. Se realizaron dos itinerarios institucionales, dos entrevistas a referentes, diez entrevistas a médicas y médicos, y un encuentro pedagógico con los y las participantes. Resultados: La mayoría de las médicas y los médicos identificaron que la revictimización, tanto en sus prácticas como en las de sus colegas, se presenta como una acción; por el contrario, con menor frecuencia, fue reconocida como una omisión. Estas situaciones se manifestaron especialmente cuando las víctimas eran adolescentes, de raza afrocolombiana, de bajos recursos económicos, trabajadoras sexuales y si el agresor fue su pareja, lo que podría reconocerse como la expresión de elementos socioculturales y políticos como el sistema patriarcal, reforzado por el modelo médico hegemónico, que ha otorgado un lugar privilegiado al campo médico del subcampo medicina moderna y un lugar subordinado a las mujeres y las niñas. Conclusión: La revictimización es una problemática que acontece en la cotidianidad de la atención a víctimas de violencia sexual y las diferentes formas en que ella se manifiesta no son reconocidas por las médicas y los médicos; identificarlas es un primer paso para generar transformaciones en la praxis de la medicina.
Evaluación de la fuerza manual: implicaciones en la salud pública y prevención de lesiones laborales
Authors:   Universidad Autónoma de Ciudad Juárez, Pacheco Cardín Mayra , Hernández Arellano Juan Luis ,   Universidad Autónoma de Ciudad Juárez, Aguilar Duque Julián Israel ,   Universidad Autónoma de Baja California
Published: July 2024

Objetivo: Este estudio aborda el desarrollo de una metodología de evaluación de la fuerza manual, investigando las diferencias y correlaciones entre ambas manos, así como entre géneros, con el fin de aportar conocimiento relevante para el diseño de políticas de prevención de lesiones laborales. Metodología: Mediante una muestra representativa y segmentada por género, se midieron las fuerzas manuales de agarre y torsión ―elementos críticos en el diseño ergonómico y en la mitigación de riesgos ocupacionales― en ambas manos, utilizando un dinamómetro y un kit de torque para medición de fuerzas. Se implementaron análisis estadísticos para evaluar la normalidad de los datos y comparar las fuerzas entre manos y géneros. Resultados: Se observó una uniformidad en la fuerza de agarre entre las manos, mientras que la fuerza de torsión fue predominantemente mayor en la mano derecha, sugiriendo dominancia manual. Aunque la fuerza de agarre se distribuyó normalmente, la de torsión presentó variaciones basadas en el género. También se identificaron diferencias significativas y una correlación positiva entre las fuerzas de ambas manos, lo que resalta la importancia de la simetría en la capacidad de fuerza para la prevención de lesiones. Conclusión: La metodología presentada proporciona un marco integral para evaluar la fuerza manual con implicaciones directas en la salud pública. Los resultados recalcan la necesidad de considerar diferencias de la fuerza manual en el diseño de intervenciones ergonómicas y protocolos de seguridad laboral. Este trabajo establece un precedente para el uso de evaluaciones de la fuerza manual en la prevención de lesiones, ofreciendo una base sólida para futuras investigaciones y aplicaciones prácticas más allá de las fronteras regionales.
REDIMAT applies Hipatia Press's Ethics Code of journals on plagiarism practices
Authors: Hipatia Press Admin
Published: July 2024

REDIMAT, in application of the Code of Ethics of Hipatia Press magazines on plagiarism practices (https://hipatiapress.com/hpjournals/index.php/redimat/editorial/antiplagio), has decided to withdraw the article titled The impact of student engagement and motivation in the statistics learning process” by Jitu Halomoan Lumbantoruan, in response of irregular practices detected.
What Motivates University Students to Counter Fake News? : Examining Situational Perceptions, Referent Criterion, and New Media Literacy
Authors: Chin Ying Shin , Zanuddin Hasmah
Published: July 2024

Fake news identification has been widely studied in the past, but research on motivating individuals, particularly university students, to fact-check news and disseminate corrective information to counter fake news is lacking. Grounded on the situational theory of problem solving (STOPS), this study aims to examine the situational perceptions and referent criterion that motivate university students to counter fake news through communicative action and examine the influence of new media literacy on the situational perceptions and referent criterion. Based on 528 responses from an online survey, new media literacy is related to all STOPS factors in countering fake news. Situational perceptions are significantly related to situational motivation in countering fake news, while situational motivation and referent criterion significantly influence communicative action. The findings extend the existing literature on countering fake news and are expected to contribute to strategic planning in future anti-fake news intervention campaigns.
Current state of the problem of assessing the quality of life in patients with cervical cancer after organ-preserving treatment
Authors: Dil O. S. , Chernyshova A. L. , Balatskaya L. N. , Truschuk Yu. M. , Chernyakov A. A.
Published: July 2024

An indicator of the effectiveness of treatment of cancer patients, in addition to oncological results, is also the preservation of their quality of life. Quality of life assessment is a modern research method that allows identifying even minor changes in any spheres of human activity in order to comprehensively determine the effectiveness of treatment. The quality of life of cancer patients is a priority and promising area of modern medicine.

The article presents information about the current state of the problem of quality of life of patients with cervical cancer after organ-preserving treatment. The results of a number of foreign studies published on this topic are presented. In addition, the results of a prospective study conducted in the Department of Gynecology of the Tomsk Oncology Research Institute are presented. In conclusion, the need for additional study of reproductive results and determining which factors need to be further evaluated, speaking of a comprehensive assessment, is shown.
Modeling the impact of using trastuzumab deruxtecan in patients with breast cancer on reducing cancer mortality in Russia
Authors: Avxentyev N. A. , Makarova Yu. V. , Makarov A. S.
Published: July 2024

Background. Reducing malignant mortality to 185 cases per 100,000 by 2030 is one of goals of the state program “Healthcare development” in Russia.

Aim. To assess potential impact of using trastuzumab deruxtecan in patients with breast cancer on reducing cancer mortality.

Materials and methods. Three indications of trastuzumab deruxtecan were considered: adult patients with HER2-positive unresectable or metastatic breast cancer that were previously treated with trastuzumab and a taxane in the advanced or metastatic setting (referred as “Second line”); adult patients with HER2-positive unresectable or metastatic breast cancer who previously received at least two lines of therapy in the metastatic setting including trastuzumab emtansine (referred as “Third line”); adult patients with HER2-low metastatic breast cancer who had received one or two previous lines of chemotherapy (referred as “HER2-low metastatic breast cancer”). The set of comparators for each clinical situation was formed based on the clinical guidelines and clinical trials of trastuzumab deruxtecan. Overall survival and treatment duration were modelled on the clinical trials basis. The model was used to estimate number of lives saved in case of transitioning all eligible patients to trastuzumab deruxtecan within a three-year horizon.

Results. Up to 3,609 patients p. a. in the “Second line” situation, 1,300 patients p. a. in the “Third line” situation and 2,260 patients p. a. in the “HER2-low breast cancer” situation can initiate trastuzumab deruxtecan treatment. In that case mortality from neoplasms could be reduced by 1,461 deaths in case of “Second line”, by 427 deaths in case of “Third line” and by 801 deaths in case of “HER2-low metastatic breast cancer” over three years. Reduction in mortality will contribute to achieving the target mortality rate from neoplasms of 21.61–24.81 %, 4.31–12.57 % and 5.91–20.89 %, respectively.

Conclusion. Using trastuzumab deruxtecan for breast cancer treatment in different clinical situations leads to quantitate reduction in cancer mortality in Russia.
The Legal Nature of the Lease Purchase Agreement: Issues of Application of the Loan Structure and Judicial Interpretation
Authors: Inshakova A. O. , Kvitsinia N. V.
Published: July 2024

The essential-substantive approach to the subinstitute of the lease purchase in civil law is to study the essence of this lease agreement through its features and essential conditions. The essence of the first order is the specifics of the lease agreement itself, and the essence of the second order is the consideration of lease purchase as a substitute. This methodological approach makes it possible to determine the place of the contract in question in civil circulation. It is argued that the study of the lease purchase agreement through its essence is the most effective method of studying a lease agreement in the system of civil law contracts. Using the example of judicial practice, the features of the leasing agreement and the reasons for its unpopularity in Russia are revealed. It has been established that judicial practice follows the path of equating leasing with credit and loan relations. This position of the courts is disputed by the authors. Legal relations under loam and leasing are distinguished, which, according to the authors, will avoid judicial errors in determining the legal nature of the lease purchase. It is proved that the lease purchase is a type of lease agreement, and not a loan or loan agreement. In a loan agreement, the borrower always becomes the owner of the subject of the agreement, and in a leasing agreement, the title of the owner of the property remains with the lessor until the end of the agreement. It is proved that the application of the interpretation of contra legem has a negative impact on the development of contract law, in particular leasing legal relations.
Technologization of Legal Solutions in the field of International Trade Compliance
Authors: Shakhnazarov B. A.
Published: July 2024

Modern technologies, and above all — information technologies, do play a significant role in navigating the complex regulatory and organizational landscape of compliance with international trade rules and management in the international trade system. The technologization of international trade compliance programs, internal compliance programs, the processes of systematization and automation of work with databases should be developed and implemented in all organizations engaged in international trade as an integral part of doing business and systematization of international trade operations. Taking into account the nature of international trade operations and their even minimal connection with specific States, in addition to clearly developing programs for compliance with international standards of trade and customs operations, the author substantiates a differentiated approach to international trade compliance, involving consideration of regulatory requirements of individual States and separate monitoring of compliance with the requirements of the State with which the relationship is associated. The author also dwells on a differentiated substantive approach to compliance procedures in trade using various software tools for monitoring and ensuring compliance in the absence, in most cases, of detailed international legal regulation (based on international treaties) of export-import operations.
ALARP Principle in Investment Law
Authors: Sukhareva E. G.
Published: July 2024

The paper is devoted to revealing the essence of the ALARP (as low as reasonably practicable) principle and the possibility of its use as one of the special principles in investment law. To substantiate the effectiveness and necessity of applying this principle in investment law, a method of analysis from the general to the specific is used. The first part of the paper analyzes general approaches to understanding legal principles, and presents the main positions on the issue of the relationship between legal principles and legislation. Then, using the example of specific branches of law, through the implementation of a comparative approach, the features of the application of the ALARP principle in each of them are derived. The author concludes that there is currently no structural and uniform application of this principle in law, and therefore the possibility of using it within the framework of investment law is justified in connection with the specifics of the legal relationship between the investor and the investment recipient when carrying out investment activities.
Medicine in the Digital Era: Legal Aspects of the Use of Cell and Gene Therapy in Foreign Countries
Authors: Ponomareva D. V. , Nekoteneva M. V.
Published: July 2024

The paper examines the experience of legal regulation of the use of cell and gene therapy products, including CAR-T technologies, in the Anglo-Saxon legal system. It is noted that a significant obstacle to the development of CAR-T therapy, as well as cell and gene therapy in general, is the absence in most countries of the world of comprehensive legal regulation of the use of such innovative methods of treating diseases. Currently, this problem is relevant for the Russian Federation, where cell and gene therapy drugs are actively being developed. The paper provides a detailed overview of the main relevant documents from Australia, the United States of America and Canada, analyzes specific cases illustrating successful law enforcement practice, and examines the mechanisms of self-regulation in the area under study. In conclusion, the authors formulate the key problems and ways to improve legal regulation as to cell and gene therapy drugs application in the Russian Federation. The authors recommend that the best practices of these foreign countries be used, taking into account its critical understanding for the development of appropriate regulatory regulation in the Russian Federation and integration associations with its participation.
Assessment of the social effectiveness of providing medical care to patients with a cardiological profile using the method of remote monitoring of blood pressure
Authors: Fedotkina Svetlana A. , Karailanov Mikhail G.
Published: July 2024

BACKGROUND: Assessing social efficiency currently plays a key role in improving the organization of medical care to citizens. Satisfaction with medical care provided is an indicator of the availability of medical care and the effectiveness of healthcare in general.
AIM: To assess the social effectiveness of medical care using the method of remote monitoring of blood pressure in cardiac patients based on the results of remote monitoring.
MATERIALS AND METHODS: The study materials included data from an anonymous sociological survey of 200 patients who were under dispensary observation and had a history of periods of deterioration in the functional state of the cardiological profile. The questionnaire offered to patients contained six establishing questions, each of which was distributed on a scale balanced from extreme positive to extreme negative assessment.
RESULTS AND DISCUSSION: Before conducting remote monitoring, the level of awareness of patients about their own health status, preventive measures, and the use of devices for remote transmission of blood pressure data from the patient to the doctor was investigated. Subsequently, to increase patient awareness, additional information materials on the procedure for interaction be-tween patients and medical workers, as well as about risk factors for the development of cardiovascular diseases and complications from them.
The sociological survey was conducted to summarize the results of remote monitoring of patients’ blood pressure and was aimed at studying patients’ opinions on changes in the organization of medical care provided in outpatient settings.
CONCLUSION: The data obtained showed that, in general, the degree of achievement of social results after remote blood pressure monitoring increased by 61.0%. Undoubtedly, such an increase in patient satisfaction was achieved as a result of the redistribution of responsibilities between doctors and nurses, as well as a result of well-established participatory interaction between medical workers and patients in terms of remote monitoring of dispensary groups of cardiac patients, instruction in the method of measuring blood pressure and monitoring it indicators in electronic form.
The effectiveness of intraoperative ultrasound control in removing foreign bodies of soft tissues in military personnel with fragmentation wounds at the stage of specialized surgical care
Authors: Dadayan Arsen R. , Protopopova Lyudmila V.
Published: July 2024

BACKGROUND: The involvement of civilian medical institutions in medical care in military conflicts and counter-terrorism operations has become an important area of the medical support system. Modern methods of surgical navigation make possible minimal invasive, effective and safe removing foreign bodies from soft tissues. Clear understanding of injuries’ character allows better planning of procedures.
AIM: Improving the results of treatment of military personnel with fragment wounds by taking into account the character of injury and the use of ultrasound control during removing soft tissue foreign bodies at the stage of specialized surgical care.
MATERIAL AND METHODS: Data from 253 case histories who were treated at the State Budgetary Institution RO “Central City Hospital named Semashko”. Indications for the removal of fragments included the size of the fragment over 7 mm, localization near to large vessels and nerve trunks, and an acute purulent process. The patients were been randomized to two groups. Group I (control) included 118 patients in whom surgery was been performed in the traditional way. Group II (main) included 135 patients in whom procedures were performed with ultrasound navigation. The research methods are ultrasound, X-ray, clinical, and statistical.
RESULTS: In 164 patients (64.8%), the wounds were of an isolated nature, where fragments were localized in various anatomical areas. 89 patients (35.2%) had combined shrapnel wounds. Of the 118 patients in group I, in whom surgery was performed in the traditional way, 65 patients (55.1%) underwent surgery under local anesthesia, 53 (44.9%) — under general anesthesia (anesthesia is always general). In 135 patients of group II, operations were performed by only one surgeon under local anesthesia. The duration of surgery, surgery invasion and wound infections rate were significantly lower in group II.
CONCLUSION: The part of isolated fragment wounds is 64.8%, combined — 35.2%. The use of ultrasound navigation during surgery can significantly improve the effectiveness of surgical treatment of patients with fragmentation wounds: reduce the invasiveness and duration of surgery, blood loss, and the rate of wound infectious complications.
processamento da concordância não redundante no português brasileiro
Authors: Scher Lilian Silva , Sampaio Thiago Oliveira da Motta
Published: July 2024

A concordância de número no português brasileiro, segundo pesquisas sociolinguísticas, apresenta um caráter variável e pode ser produzida a partir do padrão redundante, no qual há marcação de plural explícita em todos os elementos relevantes (As meninas brincam), ou a partir do padrão não redundante, no qual a marcação pode ser omitida em alguns elementos. Essa pode ser produzida de diferentes maneiras, com a marcação sendo omitida apenas no verbo (1) As meninas brincaØ) ou no verbo e no substantivo (2) As meninaØ brincaØ. O presente trabalho busca revisar as diferentes possibilidades de produção do padrão não redundante na literatura e analisar dados obtidos a partir de um experimento de produção eliciada por repetição. Além disso, buscamos averiguar o papel da saliência fônica na alternância entre os padrões de concordância. Os dados reportados sugerem que os falantes preferem modificar o padrão produzido em (2), explicitando também a marcação no substantivo e omitindo apenas no verbo, como em (1), o que explica o fato de não ter sido encontrada uma diferença significativa de processamento entre o padrão redundante e o não redundante (2) no âmbito verbal. No entanto, algumas questões metodológicas também surgiram e podem estar envolvidas nesse resultado. Por fim, a saliência fônica não se mostrou significativa na alternância entre a produção dos padrões investigados.
percepção sobre as formas de imperativo a partir dos quadrinhos da Turma da Mônica Jovem e Chico Bento Moço
Authors: Faria Carolina Barroca , Tesch Leila Maria
Published: July 2024

Neste artigo, apresentamos uma pesquisa sobre a percepção da variação linguística das formas indicativas e subjuntivas na expressão do imperativo no português brasileiro. Com base nos estudos de Scherre (2008; 2012), pôde-se constatar um aumento do uso das formas indicativas em revistas da Turma da Mônica, de 7% em 1970 para 81% em 2010 e, a partir desse resultado, a hipótese é de que os participantes de um experimento criado por nós prefiram majoritariamente as formas no indicativo, tanto na escolha de quais formas os personagens usariam quanto as formas que os participantes utilizariam. Para tanto, aplicamos um questionário, realizado na plataforma Google formulários, com recortes das revistas Turma da Mônica Jovem e Chico Bento Moço, do escritor Maurício de Sousa, para que os participantes assinalassem, em um primeiro momento, quais formas as personagens utilizariam e, em seguida, quais os próprios participantes usariam. Foram analisadas as respostas de 875 participantes, sendo a maioria desses da faixa etária jovem, do sexo feminino e residentes na Região Sudeste do Brasil. Os resultados alcançados neste estudo demonstram uma maior tendência de escolha da forma associada ao indicativo em contextos que evidenciam o traço de ruralidade dos personagens, na presença do vocativo depois do verbo, no contexto temporal imediato, em sentenças afirmativas e quando a negação é pós-verbal. Por outro lado, a forma subjuntiva é favorecida em situações comunicativas em que o contexto de autoridade está em destaque, no contexto temporal não imediato, em sentenças em que a negação é pré-verbal e na presença do vocativo antes do verbo.