bluuebunny/crossref_metadata_2025 huggingface dataset:
Polyorchidism: An Up-to-Date Systematic Review
Authors: Balawender Krzysztof , Wawrzyniak Agata , Kobos Józef , Golberg Michał , Żytkowski Andrzej , Zarzecki Michał , Walocha Jerzy , Bonczar Michał , Dubrowski Andrzej , Mazurek Agata , Clarke Edward , Polguj Michał , Wysiadecki Grzegorz , Smędra Anna
Published: January 2023

Polyorchidism is a rare male urogenital tract anomaly characterized by at least one supernumerary testis in the scrotum or ectopically. According to data based on our systematic review, 76% of the supernumerary testes (SNTs) were located in the scrotum, and 24% were extra-scrotal (p < 0.001). Among testes located outside the scrotum, 87% were found in the inguinal canal and 13% in the abdominal cavity. In 80% of cases, the diagnosis of SNT was made based on imaging tests, and the remaining 20% of cases were detected incidentally during surgery. The imaging tests performed (US or MRI) resulted in a significantly higher rate of patients who qualified for observation vs. surgical treatment (45% vs. 35%, p < 0.001). The most common conditions associated with SNT were ipsilateral inguinal hernia (15% of cases) and cryptorchidism (15% of cases). Surgery (orchidopexy/orchidectomy) was performed on 54% of patients with SNT, and the decision to observe the SNT was made in a total of 46% of patients (p = 0.001). The therapeutic approach depends on the location of the SNT and the presence of factors that raise suspicion of neoplastic proliferation.
Deepfakes Generation and Detection: A Short Survey
Authors: Akhtar Zahid
Published: January 2023

Advancements in deep learning techniques and the availability of free, large databases have made it possible, even for non-technical people, to either manipulate or generate realistic facial samples for both benign and malicious purposes. DeepFakes refer to face multimedia content, which has been digitally altered or synthetically created using deep neural networks. The paper first outlines the readily available face editing apps and the vulnerability (or performance degradation) of face recognition systems under various face manipulations. Next, this survey presents an overview of the techniques and works that have been carried out in recent years for deepfake and face manipulations. Especially, four kinds of deepfake or face manipulations are reviewed, i.e., identity swap, face reenactment, attribute manipulation, and entire face synthesis. For each category, deepfake or face manipulation generation methods as well as those manipulation detection methods are detailed. Despite significant progress based on traditional and advanced computer vision, artificial intelligence, and physics, there is still a huge arms race surging up between attackers/offenders/adversaries (i.e., DeepFake generation methods) and defenders (i.e., DeepFake detection methods). Thus, open challenges and potential research directions are also discussed. This paper is expected to aid the readers in comprehending deepfake generation and detection mechanisms, together with open issues and future directions.
Simulation of Carbon Sink of Arbor Forest Vegetation in Henan Province of China Based on CO2FIX Model
Authors: Cheng Kaili , Wu Jing , Ma Xiaozhe , Wu Leying
Published: January 2023

Mitigating carbon emissions has become a pressing concern in the process of economic development across China due to China’s key strategic goal of reaching peak carbon and carbon neutrality. Henan Province, which is located in the Central Plains, has less forest area and coverage than other areas of the nation, but consumes plenty of energy. Therefore, the quantification of Henan’s potential carbon sink is crucial for the province’s response to climate change due to the national commitment to carbon reduction targets. This research estimated the carbon sink of tree forest vegetation in Henan Province from 2019 to 2060 based on the CO2FIX model using data from the 9th Forest Inventory Report and the forest planning targets of Henan Province. The results show the following: (1) The carbon sink of existing arbor forests is mainly composed of ecological public welfare forests, and a small-year fluctuation in the carbon sink will result from the rotation of commercial forests. (2) The peak carbon sink years for existing forests and new afforestation are between the young and middle ages of the trees, and the peak of the carbon sink in Henan Province as a whole was in 2032. (3) More than 72.4% of the overall carbon sink in Henan Province’s arbor forest vegetation comes from the above-ground portion. (4) The energy substitution effect of traditional and improved cookstoves is significantly enhanced during the main cutting period of the existing commercial arbor forest in Henan Province.
Protoporphyrin IX Binds to Iron(II)-Loaded and to Zinc-Loaded Human Frataxin
Authors: Bernardo-Seisdedos Ganeko , Schedlbauer Andreas , Pereira-Ortuzar Tania , Mato José M. , Millet Oscar
Published: January 2023

(1) Background: Human frataxin is an iron binding protein that participates in the biogenesis of iron sulfur clusters and enhances ferrochelatase activity. While frataxin association to other proteins has been extensively characterized up to the structural level, much less is known about the putative capacity of frataxin to interact with functionally related metabolites. In turn, current knowledge about frataxin’s capacity to coordinate metal ions is limited to iron (II and III); (2) Methods: here, we used NMR spectroscopy, Molecular Dynamics, and Docking approaches to demonstrate new roles of frataxin; (3) Results: We demonstrate that frataxin also binds Zn2+ in a structurally similar way to Fe2+, but with lower affinity. In turn, both Fe2+-loaded and Zn2+-loaded frataxins specifically associate to protoporphyrin IX with micromolar affinity, while apo-frataxin does not bind to the porphyrin. Protoporphyrin IX association to metal-loaded frataxin shares the binding epitope with ferrochelatase; and (4) Conclusions: these findings expand the plethora of relevant molecular targets for frataxin and may help to elucidate the yet unknown different roles that this protein exerts in iron regulation and metabolism.
Impact of Hierarchical Cation-Exchange Membranes’ Chemistry and Crosslinking Level on Electrodialysis Demineralization Performances of a Complex Food Solution
Authors: Khetsomphou Elodie , Deboli Francesco , Donten Mateusz L. , Bazinet Laurent
Published: January 2023

Hierarchical cation-exchange membranes (hCEMs) fabricated by blade coating and UV crosslinking of ionomer on top of a porous substrate demonstrated promising results in performing NaCl demineralization. In the food industry, complex solutions are used and hCEMs were never investigated before for these food applications. The performances of two different coating chemistries (urethane acrylate based: UL, and acrylic acid based: EbS) and three crosslinking degrees (UL5, UL6, UL7 for UL formulations, and EbS-1, EbS-2, EbS-3 for EbS formulations) were formulated. The impacts of hCEMs properties and crosslinking density on whey demineralization performances by electrodialysis (ED) were evaluated and compared to CMX, a high performing CEM for whey demineralization by ED. The crosslinking density had an impact on the hCEMs area specific resistance, and on the ionic conductance for EbS membrane. However, 70% demineralization of 18% whey solution was reached for the first time for hCEMs without any fouling observed, and with comparable performances to the CMX benchmark. Although some properties were impacted by the crosslinking density, the global performances in ED (limiting current, demineralization duration, global system resistance, energy consumption, current efficiency) for EbS and UL6 membranes were similar to the CMX benchmark. These promising results suggest the possible application of these hCEMs (UL6, EbS-2, and EbS-3) for whey demineralization by ED and more generally complex products as an alternative in the food industry.
Evolution of the Shadow Effect with Film Thickness and Substrate Conductivity on a Hemispherical Workpiece during Magnetron Sputtering
Authors: Liu Huaiyuan , Ma Donglin , Li Yantao , You Lina , Leng Yongxiang
Published: January 2023

When depositing films on a complex workpiece surface by magnetron sputtering, the shadow effect occurs and causes the columnar structure to tilt toward the substrate owing to the oblique incident angle of the plasma flux, affecting the microstructure and properties of the films. Improving the surface diffusion could alleviate the shadow effect, whereas changing the energy of the deposited particles could improve surface diffusion. Different substrate conductivities could affect the energy of the deposited particles when they reach the substrate. In this study, Si (semiconductor) and SiO2 (insulator) sheets are mounted on the inner surface of a hemispherical workpiece, and Ti films with different thicknesses (adjusted by the deposition time) are deposited on the inner surface of the hemispherical workpiece by direct current magnetron sputtering. The results show that there is a threshold thickness and incident angle before the films are affected by the shadow effect. The threshold could be affected by the film thickness, the incident angle, and the conductivity of the substrate. The threshold would decrease as the film thickness or incidence angle increased or the conductivity of the substrate decreased. When the film thickness or incident angle does not reach the threshold, the film would not be affected by the shadow effect. In addition, the film deposited later would tilt the vertical columnar structure of the film deposited earlier. Owing to the different conductivities, the shadow effect manifest earlier for Ti films deposited on the insulator SiO2 than for films deposited on the semiconductor Si when the film thickness is >500 nm.
Comprehensive Metabolomic Fingerprinting Combined with Chemometrics Identifies Species- and Variety-Specific Variation of Medicinal Herbs: An Ocimum Study
Authors: Rai Abhishek Kumar , Khan Samreen , Kumar Akhilesh , Dubey Basant Kumar , Lal R. K. , Tiwari Ashutosh , Trivedi Prabodh Kumar , Elliott Christopher T. , Ch Ratnasekhar
Published: January 2023

Identification of plant species is a crucial process in natural products. Ocimum, often referred to as the queen of herbs, is one of the most versatile and globally used medicinal herbs for various health benefits due to it having a wide variety of pharmacological activities. Despite there being significant global demand for this medicinal herb, rapid and comprehensive metabolomic fingerprinting approaches for species- and variety-specific classification are limited. In this study, metabolomic fingerprinting of five Ocimum species (Ocimum basilicum L., Ocimum sanctum L., Ocimum africanum Lour., Ocimum kilimandscharicum Gurke., and Hybrid Tulsi) and their varieties was performed using LC-MS, GC-MS, and the rapid fingerprinting approach FT-NIR combined with chemometrics. The aim was to distinguish the species- and variety-specific variation with a view toward developing a quality assessment of Ocimum species. Discrimination of species and varieties was achieved using principal component analysis (PCA), partial least squares discriminate analysis (PLS-DA), data-driven soft independent modelling of class analogy (DD-SIMCA), random forest, and K-nearest neighbours with specificity of 98% and sensitivity of 99%. Phenolics and flavonoids were found to be major contributing markers for species-specific variation. The present study established comprehensive metabolomic fingerprinting consisting of rapid screening and confirmatory approaches as a highly efficient means to identify the species and variety of Ocimum, being able to be applied for the quality assessment of other natural medicinal herbs.
Metal Source and Fluid Evolution in Xiaojiashan Gold Deposit in Northeastern Hunan, China: Implications of Rare Earth Elements, Fluid Inclusions, and Pyrite S Isotopic Compositions
Authors: Hou Dongzhuang , Lin Shu , Liu Lang , Huan Chao , Qiu Huafu , Tu Bingbing
Published: January 2023

The material source and the evolution of ore-forming hydrothermal fluids of Xiaojiashan gold deposits remain controversial. We carried out a mineralogical characteristics analysis, trace elements analysis, sulfur isotope composition analysis, and fluid inclusion microthermometry in order to explore the ore-forming sources, conditions, and process of this deposit. Gold mineralization can be divided into three stages: the quartz-pyrite stage, the quartz-polymetallic sulfide stage, and the quartz-ankerite stage. This gold deposit was probably formed under the following conditions: temperature of 122–343 °C and salinity of 0.8–11.4 wt% (NaCl). It was inferred that the ore-forming hydrothermal fluids were early metamorphic–hydrothermal (Stage I) and late magmatic–hydrothermal (Stages II and III), and were characterized by medium–low temperature and medium–low salinity based on fluid inclusion microthermometry and S isotope composition. The temperature and salinity of the ore-forming fluid decreased during mineralization, which was caused by the involvement of groundwater. The chondrite-normalized trace element patterns of the gold ores are similar to the host rocks of the Lengjiaxi Formation, indicating that the ore-forming materials were sourced from the Lengjiaxi Formation. The S isotopes indicated that the magmatic components also provided the ore-forming materials during Stages II and III.
Aramid Nanofiber/XNBR Nanocomposite with High Mechanical, Thermal, and Electrical Performance
Authors: Wang Jingyi , Zhang Xumin , Wen Yanwei , Chen Yang , Fu Quansheng , Wang Jing , Jia Hongbing
Published: January 2023

Aramid nanofibers (ANFs) were successfully produced by deprotonation of Kevlar fiber followed by grafting epichlorohydrin in dimethyl sulfoxide solution. The ANFs were then incorporated into carboxylated acrylonitrile butadiene rubber (XNBR) by means of latex blending, followed by vulcanization. The interaction between ANFs and XNBR, and the effects of ANFs on the mechanical strength, dielectric properties, and thermal stability of ANF/XNBR nanocomposites were investigated. The results revealed that hydrogen bonding and covalent bonding interactions existed between ANFs and the XNBR matrix and played a critical role in the reinforcement of ANFs to XNBR nanocomposites. After adding 5 phr (parts per hundred rubber) of ANFs, the XNBR nanocomposite exhibited a significant improvement in mechanical properties, namely a 182% increase in tensile strength and a 101% increase in tear strength. In addition, the dielectric constant and thermal properties of ANF/XNBR also increased dramatically. ANFs may thus make an ideal candidate for high-performance rubber materials.
Development of MOF Based Recyclable Photocatalyst for the Removal of Different Organic Dye Pollutants
Authors: Kitchamsetti Narasimharao , Chakra Chidurala Shilpa , De Barros Ana Lucia Ferreira , Kim Daewon
Published: January 2023

The preparation of metal organic frameworks (MOFs) has come to the forefront in recent years because of their outstanding physical and chemical properties. Many MOFs such as Zn, Co, Ni, Fe, and Ag, etc., have been successfully synthesized. In this work, we followed the solvothermal assisted route to synthesize Ag-MOF (abbreviated as AMOF) nanosheets and then applied them as a photocatalyst to remove different organic pollutants, namely methyl orange (MO), crystal violet (CV), and methylene blue (MB). Chemical composition, optical properties, morphology, and microstructural analysis were analyzed using XPS, UV-visible spectrophotometer, FESEM, TEM, and EDS, respectively. The structural properties of AMOF nanosheets were studied by X-ray diffraction (XRD). Nitrogen adsorption and desorption isotherm analysis were utilized to evaluate the specific surface area and pore size of the AMOF nanosheets. Further, AMOF nanosheets showed notable photocatalytic performance for various dye pollutants degradation. The results confirmed 74.5, 85.5, and 90.7% of MO, CV, and MB dye pollutants removal after 120 min of irradiation with the rate constants (k) of 0.0123, 0.0153, and 0.0158 min−1, respectively. The effect of superoxide radicals (O2−) and photogenerated holes (h+) on the organic dye pollutants removal was investigated using radical scavenger trapping studies. Moreover, the stability study also confirmed the recyclability of the photocatalyst. Therefore, the findings of this research present a realizable method to grow AMOF photocatalyst for successful degradation of various dye pollutants.
An Inventory of Anthelmintic Plants across the Globe
Authors: Ahmed Haroon , Kilinc Seyma Gunyakti , Celik Figen , Kesik Harun Kaya , Simsek Sami , Ahmad Khawaja Shafique , Afzal Muhammad Sohail , Farrakh Sumaira , Safdar Waseem , Pervaiz Fahad , Liaqat Sadia , Zhang Jing , Cao Jianping
Published: January 2023

A wide range of novelties and significant developments in the field of veterinary science to treat helminth parasites by using natural plant products have been assessed in recent years. To the best of our knowledge, to date, there has not been such a comprehensive review of 19 years of articles on the anthelmintic potential of plants against various types of helminths in different parts of the world. Therefore, the present study reviews the available information on a large number of medicinal plants and their pharmacological effects, which may facilitate the development of an effective management strategy against helminth parasites. An electronic search in four major databases (PubMed, Scopus, Web of Science, and Google Scholar) was performed for articles published between January 2003 and April 2022. Information about plant species, local name, family, distribution, plant tissue used, and target parasite species was tabulated. All relevant studies meeting the inclusion criteria were assessed, and 118 research articles were included. In total, 259 plant species were reviewed as a potential source of anthelmintic drugs. These plants can be used as a source of natural drugs to treat helminth infections in animals, and their use would potentially reduce economic losses and improve livestock production.
Repeated Tick Infestations Impair Borrelia burgdorferi Transmission in a Non-Human Primate Model of Tick Feeding
Authors: Narasimhan Sukanya , Booth Carmen J. , Philipp Mario T. , Fikrig Erol , Embers Monica E.
Published: January 2023

The blacklegged tick, Ixodes scapularis, is the predominant vector of Borrelia burgdorferi, the agent of Lyme disease in the USA. Natural hosts of I. scapularis such as Peromyscus leucopus are repeatedly infested by these ticks without acquiring tick resistance. However, upon repeated tick infestations, non-natural hosts such as guinea pigs, mount a robust immune response against critical tick salivary antigens and acquire tick resistance able to thwart tick feeding and Borrelia burgdorferi transmission. The salivary targets of acquired tick resistance could serve as vaccine targets to prevent tick feeding and the tick transmission of human pathogens. Currently, there is no animal model able to demonstrate both tick resistance and diverse clinical manifestations of Lyme disease. Non-human primates serve as robust models of human Lyme disease. By evaluating the responses to repeated tick infestation, this animal model could accelerate our ability to define the tick salivary targets of acquired resistance that may serve as vaccines to prevent the tick transmission of human pathogens. Towards this goal, we assessed the development of acquired tick resistance in non-human primates upon repeated tick infestations. We report that following repeated tick infestations, non-human primates do not develop the hallmarks of acquired tick resistance observed in guinea pigs. However, repeated tick infestations elicit immune responses able to impair the tick transmission of B. burgdorferi. A mechanistic understanding of the protective immune responses will provide insights into B. burgdorferi-tick–host interactions and additionally contribute to anti-tick vaccine discovery.
The Arabidopsis LHT1 Amino Acid Transporter Contributes to Pseudomonas simiae-Mediated Plant Growth Promotion by Modulating Bacterial Metabolism in the Rhizosphere
Authors: Agorsor Israel D. K. , Kagel Brian T. , Danna Cristian H.
Published: January 2023

The root microbiome structure ensures optimal plant host health and fitness, and it is, at least in part, defined by the plant genotype. It is well documented that root-secreted amino acids promote microbial chemotaxis and growth in the rhizosphere. However, whether the plant-mediated re-uptake of amino acids contributes to maintaining optimal levels of amino acids in the root exudates, and, in turn, microbial growth and metabolism, remains to be established. Here, we show that Lysine-Histidine Transporter-1 (LHT1), an amino acid inward transporter expressed in Arabidopsis thaliana roots, limits the growth of the plant-growth-promoting bacteria Pseudomonas simiae WCS417r (Ps WCS417r). The amino acid profiling of the lht1 mutant root exudates showed increased levels of glutamine, among other amino acids. Interestingly, lht1 exudates or Gln-supplemented wild-type exudates enhance Ps WCS417r growth. However, despite promoting bacterial growth and robust root colonization, lht1 exudates and Gln-supplemented wild-type exudates inhibited plant growth in a Ps WCS417r-dependent manner. The transcriptional analysis of defense and growth marker genes revealed that plant growth inhibition was not linked to the elicitation of plant defense but likely to the impact of Ps WCS417r amino acids metabolism on auxin signaling. These data suggest that an excess of amino acids in the rhizosphere impacts Ps WCS417r metabolism, which, in turn, inhibits plant growth. Together, these results show that LHT1 regulates the amino-acid-mediated interaction between plants and Ps WCS417r and suggest a complex relationship between root-exuded amino acids, root colonization by beneficial bacteria, bacterial metabolism, and plant growth promotion.
Allelopathic Substances of Osmanthus spp. for Developing Sustainable Agriculture
Authors: Kato-Noguchi Hisashi , Hamada Yuri , Kojima Misuzu , Kumagai Sanae , Iwasaki Arihiro , Suenaga Kiyotake
Published: January 2023

Osmanthus fragrans Lour. has been cultivated for more than 2500 years because of the fragrance and color of the flowers. The flowers and roots have been used in tea, liquors, foods, and traditional Chinese medicine. The species contains more than 180 compounds including terpenoids, phenylpropanoids, polyphenols, flavonoids, and sterols. However, there has been limited information available on the allelopathic properties and allelopathic substances of O. fragrans. We investigated the allelopathy and allelopathic substances of O. fragrans and Osmanthus heterophyllus (G.Don) P.S. Green, as well as Osmanthus × fortunei Carrière, which is the hybrid species between O. fragrans and O. heterophyllus. The leaf extracts of O. fragrans, O. heterophyllus, and O. × fortunei suppressed the growth of cress (Lepidium sativum L.), alfalfa (Medicago sativa L.), Lolium multiflorum Lam., and Vulpia myuros (L.) C.C.Gmel with the extract concentration dependently. The extract of the hybrid species O. × fortune was the most active among the extracts. The main allelopathic substances of O. × fortunei and O. fragrans were isolated and identified as (+)-pinoresinol and 10-acetoxyligustroside, respectively. (+)-Pinoresinol was also found in the fallen leaves of O. × fortunei. Both compounds showed an allelopathic activity on the growth of cress and L. multiflorum. On the other hand, several allelopathic substances including (+)-pinoresinol may be involved in the allelopathy of O. heterophyllus. O. fragrans, O. heterophyllus, and O. × fortunei are evergreen trees. but their senescent leaves fall and cover the soil under the trees. It is possible that those allelopathic substances are liberated through the decomposition process of the leaves into their rhizosphere soil, and that they accumulate in the soil and provide a competitive advantage to the species through the inhibition of the growth of the neighboring competing plants. Therefore, the leaves of these Osmanthus species are allelopathic and potentially useful for weed management options in some agriculture settings to reduce commercial herbicide dependency for the developing sustainable agriculture systems.
How Tree Decline Varies the Anatomical Features in Quercus brantii
Authors: Soheili Forough , Abdul-Hamid Hazandy , Almasi Isaac , Heydari Mehdi , Tongo Afsaneh , Woodward Stephen , Naji Hamid Reza
Published: January 2023

Drought has serious effects on forests, especially semi-arid and arid forests, around the world. Zagros Forest in Iran has been severely affected by drought, which has led to the decline of the most common tree species, Persian oak (Quercus brantii). The objective of this study was to determine the effects of drought on the anatomical structure of Persian oak. Three healthy and three declined trees were sampled from each of two forest sites in Ilam Forest. Discs were cut at breast height, and three sapwood blocks were taken near the bark of each tree for sectioning. The anatomical characteristics measured included fiber length (FL), fiber wall thickness (FWT), number of axial parenchymal cells (NPC), ray number (RN), ray width (RW), and number of calcium oxalate crystals. Differences between healthy and declined trees were observed in the abundance of NPC and in RN, FL, and FWT, while no differences occurred in the number of oxalate crystals. The decline had uncertain effects on the FL of trees from sites A and B, which showed values of 700.5 and 837.3 μm compared with 592.7 and 919.6 μm in healthy trees. However, the decline resulted in an increase in the FWT of trees from sites A and B (9.33 and 11.53 μm) compared with healthy trees (5.23 and 9.56 μm). NPC, RN, and RW also increased in declined individuals from sites A and B (28.40 and 28.40 mm−1; 41.06 and 48.60 mm−1; 18.60 and 23.20 μm, respectively) compared with healthy trees (20.50 and 19.63 mm−2; 31.60 and 28.30 mm−2; 17.93 and 15.30 μm, respectively). Thus, drought caused measurable changes in the anatomical characteristics of declined trees compared with healthy trees.
LC–HRMS for the Identification of Quercetin and Its Derivatives in Spiraea hypericifolia (Rosaceae) and Anatomical Features of Its Leaves
Authors: Petrova Natalia V. , Chernonosov Alexander A. , Koval Vladimir V. , Andreeva Valeriya Yu. , Erst Andrey S. , Kuznetsov Alexander A. , Kulikovskiy Maxim S. , Wang Wei , Yu Sheng-Xiang , Kostikova Vera A.
Published: January 2023

Spiraea hypericifolia L. is affiliated with the section Chamaedryon Ser. of the genus Spiraea L. (Rosaceae). Similar to many other Spiraea species, S. hypericifolia most often accumulates flavonols among other flavonoids, in particular quercetin and its derivatives. An ethanol–water extract from the aerial part of S. hypericifolia collected in the vicinity of the Ilyichovo settlement (Krasnoyarsk Krai, Russia) was analyzed by liquid chromatography with high-resolution mass spectrometry. Primary and secondary metabolites were found in the extract; structural interpretation consistent with quercetin and its derivatives was proposed for 10 of them. Major compounds were various glycosides of quercetin containing glucose (four compounds), galactose (one compound), xylose (two compounds), arabinose (one compound), or rutinose (one compound) as a carbohydrate residue. Isorhamnetin and 3-O-methylquercetin-3′-O-β-D-glucopyranoside were identified among methyl-containing compounds. The latter compound and reynoutrin, rhamnetin-3-O-β-D-xylopyranosyl-β-D-glucopyranoside, and quercetin-3-O-(6″-O-malonyl)-β-D-glucoside have not been previously found in S. hypericifolia. Data on the presence of quercetin and its derivatives in the extract of S. hypericifolia expand the understanding of the possible practical use of this plant. In addition, the microscopic features of S. hypericifolia leaves were studied. The diagnostic features of the leaf blade necessary for the authentication of raw materials were revealed: straight-walled epidermis cells, stomata located on both sides of the leaf blade (amphistomatic type), two types of trichomes, and wrinkled cuticula with nodi. The main anatomical diagnostic features of the leaves of S. hypericifolia were determined, which makes it possible to assess the authenticity of the raw material.
A atuação do enfermeiro no combate à sífilis na atenção primária à saúde: uma revisão de literatura
Authors: Melo Adriele Martins , Moreira Cássia Borges Maciel , Pinto Emanuele Cardoso , Ferreira Evelin Amanda Martins , Meireles Ingrid Marcela Duarte , Blanc Lucas Torrinha , Costa Maria Tainã do Nascimento
Published: January 2023

A sífilis é conhecida há séculos como uma infecção bacteriana sistêmica, crônica e exclusiva do ser humano. Causada pela bactéria Treponema pallidum, subespécie pallidum, tendo o contato sexual como principal modo de transmissão, a doença se manifesta nos estágios primário, secundário, latente e terciário. Logo, o objetivo geral deste presente artigo é buscar na literatura a assistência do enfermeiro na atenção primária mediante a sífilis adquirida. Para tanto, realizou-se como tipo de pesquisa uma revisão integrativa da literatura. As bases de dados utilizadas estão inseridas na Biblioteca Virtual de Saúde (BVS), dentre elas, a Scielo (Scientific Electronic Library Online) e Google Acadêmico Os resultados demonstram que o diagnóstico é feito mediante o teste treponêmico reagente, conduzindo o paciente e seu parceiro orientações sobre a importância do início do tratamento, a fim de quebrar a cadeia de contaminação, proporcionando a possibilidade de cura. Considera-se fundamental a assistência do enfermeiro com ações estratégicas na atenção primária diante ao diagnóstico positivo de sífilis, seguindo os protocolos do Ministério da Saúde.
Prevalência de Melasma em mulheres residentes no Distrito Federal e os impactos na qualidade de vida
Authors: Avelino Andressa Cirqueira , Barros Bianca de Sousa , Paiva Letícia Martins , Boscato Kelly Letícia
Published: January 2023

O melasma é uma hipermelanose cutânea crônica que se manifesta por meio de manchas hiperpigmentadas assintomáticas, irregulares e simétricas, que predominam principalmente na face. O presente estudo teve como objetivo identificar os impactos emocionais e sociais que essa disfunção estética desencadeia em seu portador, assim como analisar a sua influência na qualidade de vida e identificar possíveis dificuldades no controle das manchas. Trata-se de um estudo quantitativo transversal, realizado com 31 mulheres, portadoras de melasma, residentes no Distrito Federal. Foi aplicado um questionário eletrônico de 28 questões adaptado para esse estudo e enviado por meio de redes sociais. Os dados foram analisados descritivamente. O estudo mostrou que o melasma acomete mulheres na faixa etária média de 37,9, com predominância do fototipo III. A incidência foi maior durante ou após a gestação. Das participantes, 54,8% (n=17)  realizaram tratamento com ácidos, como, hidroquinona, tretinoína, kójico e tranexâmico. Dessas, onze relataram que as manchas voltaram e seis relataram efeito satisfatório após o tratamento. Queixas quanto a aparência da pele, frustração e constrangimento de maneira geral foram as mais relatadas. Evidencia-se a importância da realização de futuras pesquisas que tenham como proposição a realização de correlações estatísticas para melhor interpretação e validação dos dados obtidos.
Tratamentos disponíveis e o manejo da capsulite adesiva do ombro: uma revisão bibliográfica
Authors: Neto Felipe Leite , Curi Sílvia Goulart , Oliveira Pietro Burgarelli Romaneli de
Published: January 2023

INTRODUÇÃO: a capsulite adesiva do ombro é uma condição médica sem etiologia completamente esclarecida que se apresenta como dor intensa e redução progressiva dos movimentos dessa articulação, sendo mais prevalente em mulheres e com pico de incidência entre 40  e 60 anos de idade, diabéticos e indivíduos com história prévia de longo período de imobilização. OBJETIVOS: conhecer a analisar as evidências disponíveis acerca dos protocolos de tratamento da patologia. MATERIAIS E MÉTODOS: revisão bibliográfica por meio de pesquisa na literatura em bases de dados reconhecidas, com busca por informações, resultados, evidências e comprovações de estudos já realizados por outros autores previamente. DISCUSSÃO: existem diversas abordagens terapêuticas disponíveis, dentre as quais se tem o bloqueio nervoso para manipulação não dolorosa, terapia cirúrgica reconstrutiva e reabilitação fisioterápica. CONCLUSÃO: o tratamento da capsulite adesiva não apresenta base protocolar pré-definida, uma vez que deve ser realizado conforme o estadiamento do quadro e rede de apoio do paciente.
Tratamento restaurador onlay em paciente com Síndrome de Down: relato de caso clínico
Authors: Avelino André Victor Damasceno , Bentes Wallace Bruno Matos , Dias Mariane Gomes de Castro Mota , Brito Maria Eduarda dos Santos , Lima Myrella Mikaela de Araújo , De Souza Gabriel Catunda , Varejão Livia Coutinho
Published: January 2023

Na Odontologia são considerados pacientes portadores de necessidades especiais (PNEs), aqueles que precisam de serviço odontológico diferenciado. De acordo com dados epidemiológicos cerca de 24% da população brasileira apresentava algum tipo de deficiência. A Síndrome de Down (SD) é o exemplo mais evidente de PNE, também chamada de trissomia 21, definida por uma demora no progresso das funções motoras e de fala, principalmente o retardo mental. A SD pode apresentar-se em grau leve, moderada ou grave e profunda. Suas características clínicas bucais envolvem micrognatia, língua fissurada, palato estreito alto e ogival, anodontias, modificação na sequência de erupção dentária, entre outros.  Restaurações que utilizam técnicas do tipo indiretas exibem uma grande vantagem no atendimento odontológico para pacientes com deficiências, pois proporcionam um procedimento menos traumático. Desta forma o trabalho tem como objetivo relatar um caso clínico de Tratamento restaurador do tipo onlay em um paciente portador de Síndrome de Down. Paciente de gênero masculino, 38 anos, portador de SD, procurou a clínica-escola do curso de Odontologia do Centro Universitário Fametro apresentando como queixa principal “Quero fazer a troca da prótese pois já passou muito tempo de uso, e fazer restauração”. Ao realizar o exame intraoral, observou-se uma extensa restauração insatisfatória em resina composta nas faces mésio-oclusal (classe II) do elemento 16, nesse sentido optou-se substituí-la por uma restauração indireta do tipo onlay. Diante do presente relato de caso, constatou-se a importância do manejo diferenciado ao paciente PNE, para que haja uma adequada devolução da função anatômica e oclusal, nesse sentido cabe ao profissional cirurgião- dentista se atentar às peculiaridades de cada paciente para executar medidas corretas,proporcionado uma melhor qualidade de vida ao indivíduo.
Alfabetização e o letramento matemático na perspectiva da etnomatemática
Authors: Melo Juliana Matos de , Menezes Jeane Denise de Souza , Santos Leila Patrícia , Fernandes Gisele Santos , Santos Mariana Florêncio dos , Santiago Ana Rita
Published: January 2023

Esse texto tem por objetivo apresentar alguns conceitos que fundamentaram a pesquisa sobre a Alfabetização e o letramento matemático na perspectiva da etnomatemática, que almeja investigar o processo de alfabetização, letramento e letramento matemático, considerando-os como processos indissociáveis no período da escolarização. A escola, como instituição formadora e com função social, precisa aliar a alfabetização ao letramento num modo eficaz na formação dos(das) alunos(as). As análises bibliográficas desse estudo foram feitas a partir da década de 1980 por ser um marco divisor na educação brasileira, na qual autores como D´Ambrósio (1998), Deleuze e Guattari (1995) e Soares (1998) tiveram grandes destaques. A etnomatemática dialoga de forma significativa e corrobora com o letramento matemático, pois apresenta uma pedagogia dialética com o presente estudo, dando-nos respostas às questões como: culturais, as práticas pedagógicas (KNIJNIK, 2019). Este estudo de revisão bibliográfica mostrou que alfabetizar letrando é um imperativo ético na formação das crianças, pois, apenas decodificar letras e sons, palavras e símbolos não levam os sujeitos a pensar a sociedade que temos e transformá-la naquela que queremos. O letramento matemático viabiliza o processo com os números, com as formas de contar e leva os(as) alunos(as), a saber interpretar o mundo e codificá-lo de acordo com as suas necessidades mais básicas, até mesmo de subsistência, fazendo uso da educação recebida na escola uma ponte com os saberes adquiridos fora dela. Assim o(a) educando(a) terá condições de lutar por melhores condições de vida e ainda transformar a sociedade de forma mais justa e igualitária.
Impactos da pandemia de COVID-19 no Custo Unitário Básico (CUB) da construção civil no estado de Rondônia, Brasil
Authors: Da Silva Neto Miguel José , Leal Matheus Lucas Maciel
Published: January 2023

A construção civil teve um grande impacto causado pela pandemia de COVID-19 que iniciou em março de 2020, influenciando diversos setores econômicos do país. Além de fortalecer a economia, o setor é também capaz de proporcionar desenvolvimento social, pois é responsável pela geração de muitos empregos e tem grande impacto no produto interno bruto (PIB) do Brasil. Na Construção Civil esse impacto pode ser medido pela variação do Custo Unitário Básico (CUB/m²) da construção do projeto-padrão baixo, padrão normal e padrão alto, que é um indicador que serve de base para analisar parte dos custos de construção dos edifícios. Neste contexto, a presente pesquisa objetiva analisar a variação no Custo Unitário Básico no período de 2019 a 2022 visando identificar o impacto da pandemia no contexto da Engenharia Civil no estado de Rondônia. Para isso, foram utilizadas informações disponíveis no website do Sindicato da Indústria da Construção Civil do Estado de Rondônia (SINDUSCON/RO) e do Sistema Nacional de Pesquisas de Custos e Índices da Construção Civil (SINAPI). Os dados que se referem aos custos da construção de projetos de padrão residencial (baixo, normal e alto) foram organizados trimestralmente e foram calculadas médias e percentuais objetivando identificar sua variação ao longo do período de estudo. Os resultados mostram que todos os padrões residenciais apresentaram aumento no custo, principalmente no período de 2020 a 2021, que foi seu ápice. Todavia, é possível identificar tendência de redução dos preços a partir de 2021, o que pode ser um indicativo de que as empresas do setor estão buscando novas estratégias de negócios.
Acompanhamento dos discentes de medicina: uma estratégia de escuta pelo núcleo de experiência discente
Authors: Barros Roberya Viana de , Silveira Jandira Silva da , Fonseca Rachel Cavalcanti
Published: January 2023

O acompanhamento psicopedagógico é a forma mais simples de escuta do aluno e suas perspectivas a respeito do processo de ensino-aprendizagem. No estágio do Internato onde os alunos estão inseridos no campo de prática torna-se essencial a escuta e o diálogo, em busca de um melhor desempenho do aluno. Cada aluno possui uma visão e um desempenho específico, deste modo, é fundamental o acompanhamento personalizado deles, torna-se favorável o melhor empenho do aluno e seu engajamento nas práticas médicas.
Development of the fuzzy logic algorithm of data survey and analysis for disaster relief systems
Authors:   Starovoytov Center of  Information Technologies and Systems for Executive Power Authorities, Sinitsyn A.V. , Lisay N.Yu. , Sinitsyn A.A. , Buykin A. Yu. ,   MIREA – Russian Technological University
Published: January 2023

The article is devoted to the development of an algorithm for collecting and analyzing data with fuzzy logic about the need for a resource in logistics zones under emergency circumstances to create a prototype management decision support system.
Application of artificial intelligence technologies to solve problems of improving the efficiency of metrological support of organizational and technical systems
Authors:   Starovoitov Center of Information Technologies and Systems of Executive Power Authorities, Krasavina A.A.
Published: January 2023

the article is devoted to the problems of improving the efficiency of the metrological support system of the Armed Forces of the Russian Federation with the use of advanced information technologies of artificial intelligence. The efficiency indicator of the system under study is presented and justified, the mathematical apparatus for assessing and predicting the state (efficiency of functioning) of the metrological support system for training and testing an artificial intelligence system in an automated control system for the forces and means of metrological support of the Armed Forces of the Russian Federation is presented.
Principles of project management
Authors:   Starovoytov Center of  Information Technologies and Systems for Executive Power Authorities, Gavrilova N.А. , Filippov V.I. ,   International Center for Informatics and Electronics
Published: January 2023

The article is devoted to the principles of project management, which is one of the modern areas of management. The principles of project management used in various project management methodologies are considered.
Effects of Three Training Methods on the Physical Fitness in Adult Cameroonian Boxers
Authors: Hugues Djofang , Lamou Bonoy , Jean-Pierre Mbame , Edmond Ebal Minye , Evariste Edmondo Djomo Ngnoko , Pascale Mibo’o , Germain Taiwe Sotoing
Published: January 2023

This study aimed to evaluate three training methods on the physical capacity of Cameroonians boxers in other to propose the best method for their preparation. Thus, thirty-six boxers aged twenty-three to twenty-six were recruited and divided into three groups of twelve boxers each. They were submitted to training session for eight weeks using the continuous method, the intermittent method and the mixed method for group one, two and three respectively. Anthropometric (weight, height and Body Mass Index (BMI)) and physiological (Maximal Oxygen Consumption (VO2max), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Blood Glucose Levels (BGL) and Blood Lactic Acid concentrations (BLA)) parameters were measured before and after the training session program. Results at the end of the program showed no significant variation of Blood Glucose Level of boxers between the three groups as well as inside the same group (p>0.05). On the other hand, significant differences (p<0.05-p<0.001) in weight, BMI, SBP, DBP, VO2max and Blood Lactic Acid concentrations were observed. Indeed, weight, BMI, SBP and DBP decreased significantly (p<0.05-p<0.001), while VO2max increased significantly in the three experimental groups (p<0.05-p<0.001). The analysis of these results reveals that the group having practiced the mixed training method showed the strongest rates of increase in VO2max (67.8±5.00 ml/min/kg). In addition, their VO2max at the end of the experimentation is largely above the average value defined by literature (64.8 ml/min/kg). This can justify the choice of the mixed training method for the physical preparation of Cameroonian boxers.
The effect of osteopathic manipulative treatment on heart rate variability: A case study in a female World Championship medaling open-water swimmer
Authors: R Pla , M Bril
Published: January 2023

To examine the effect of osteopathic manipulative treatment (OMT) on heart rate variability (HRV) indices in an elite open-water swimmer. A female open-water swimmer (age =28 years, height = 172 cm, body mass = 60 kg) participated in this study. The swimmer performed a daily supine HRV test routine 12 days before the 2019 open-water World Championships. OMT was administered when parasympathetic activity (based on HRV indices) was considered below normal values. The swimmer won a bronze medal in the 25 km event and placed fourth in the 10 km event, which qualified her for the 2020 Tokyo Olympics. Parasympathetic falls occurred three times during the taper period. After OMT, we observed a rebound of parasympathetic activity with a moderate to strong increase for High Frequency (HF) values compared with the average baseline from 10 to 150% increase of Ln HF values. OMT appeared to allow a parasympathetic rebound and increase the quality of recovery in an elite open-water swimmer who performed well during the World Championships. This case report illustrates the potential effects of OMT on autonomous nervous system activity, highlighting the possibilities to improve the quality of recovery in world-class athletes. It also shows the necessity to implement individualized training in the context of elite sports.
Impression management in reporting environmental information in groups of the energy, raw materials and fuel sectors. Evidence from Poland
Authors: Bąk Melania , Strojek-Filus Marzena
Published: January 2023

Impression management is vital in disclosing non-financial information, including environmental information, in integrated reports. The purpose of the study is to identify and assess the effects of using the impression management strategies in presenting non-financial ecological knowledge in the integrated reports issued by capital groups from the energy, raw materials and fuel sectors, which have had a large share in the degradation of the natural environment for many years. The research was conducted based on two stages: the first stage – as part of the impression management strategy – focused on text analysis to identify the tools for thematic manipulation as well as visual and structural manipulation, and the second stage consisted in analysing the level of text readability using, i.a., FOG and Pisarek indices. The research findings regarding the selected business entities identified as the “polluters” of the natural environment confirm the application of various tools as part of the stakeholder impression management strategies, including manipulation using words, colour, pictures and text.