bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure Legends from EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1
Authors: Wu Kongming , Li Zhaoming , Cai Shaoxin , Tian Lifeng , Chen Ke , Wang Jing , Hu Junbo , Sun Ye , Li Xue , Ertel Adam , Pestell Richard G.
Published: April 2023

Supplementary Figure Legends - PDF file 71K, Supplementary Figure Legends
Supplementary Figure 5 from A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance
Authors: Zhou Bingsen , Su Leila , Hu Shuya , Hu Weidong , Yip M.L. Richard , Wu Jun , Gaur Shikha , Smith D. Lynne , Yuan Yate-Ching , Synold Timothy W. , Horne David , Yen Yun
Published: April 2023

PDF file - 68K, Supplemental figure 5: Effect of COH20 and COH29 on proliferation of NCI 60 Cancer cell panel.
Supplementary Figure 3 from EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1
Authors: Wu Kongming , Li Zhaoming , Cai Shaoxin , Tian Lifeng , Chen Ke , Wang Jing , Hu Junbo , Sun Ye , Li Xue , Ertel Adam , Pestell Richard G.
Published: April 2023

Supplementary Figure 3 - PDF file 157K, Supplementary Figure 3. EYA1 induction of SK BR3 cellular proliferation requires the EYA1 phosphatase domain
Supplementary Figure 4 from A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance
Authors: Zhou Bingsen , Su Leila , Hu Shuya , Hu Weidong , Yip M.L. Richard , Wu Jun , Gaur Shikha , Smith D. Lynne , Yuan Yate-Ching , Synold Timothy W. , Horne David , Yen Yun
Published: April 2023

PDF file - 85K, Supplemental figure 4: Cell cycle analysis of effects of COH29 on KB cells.
Supplementary Figure 2 from EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1
Authors: Wu Kongming , Li Zhaoming , Cai Shaoxin , Tian Lifeng , Chen Ke , Wang Jing , Hu Junbo , Sun Ye , Li Xue , Ertel Adam , Pestell Richard G.
Published: April 2023

Supplementary Figure 2 - PDF file 53K, Supplementary Figure 2. MDA-MB-231 cells transduced with EYA1 shRNA or vector control were subjected to RT-PCR analysis for the relative abundance of cyclin D1 and EYA1
Figure S5 from Hbo1 Is a Cyclin E/CDK2 Substrate That Enriches Breast Cancer Stem-like Cells
Authors: Duong MyLinh T. , Akli Said , Macalou Sira , Biernacka Anna , Debeb Bisrat G. , Yi Min , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

Figure S5: Hbo1 knockdown in T1G4.2 cells reverts the gene expression signature associated with the EMT.
Figure S4 from Hbo1 Is a Cyclin E/CDK2 Substrate That Enriches Breast Cancer Stem-like Cells
Authors: Duong MyLinh T. , Akli Said , Macalou Sira , Biernacka Anna , Debeb Bisrat G. , Yi Min , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

Figure S4: Cyclin E/CDK2 phosphorylation of Hbo1 does not affect the HAT activity of Hbo1.
Figure S3 from Hbo1 Is a Cyclin E/CDK2 Substrate That Enriches Breast Cancer Stem-like Cells
Authors: Duong MyLinh T. , Akli Said , Macalou Sira , Biernacka Anna , Debeb Bisrat G. , Yi Min , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

Figure S3: Identification of human EL/CDK2 and LMW-E/CDK2 substrates using the ProtoArray microarray.
Supplementary Figure 1 from Preventing Postoperative Metastatic Disease by Inhibiting Surgery-Induced Dysfunction in Natural Killer Cells
Authors: Tai Lee-Hwa , de Souza Christiano Tanese , Bélanger Simon , Ly Lundi , Alkayyal Almohanad A. , Zhang Jiqing , Rintoul Julia L. , Ananth Abhirami A. , Lam Tiffany , Breitbach Caroline J. , Falls Theresa J. , Kirn David H. , Bell John C. , Makrigiannis Andrew P. , Auer Rebecca A.
Published: April 2023

PDF file - 142K, Surgery does not alter non-NK immune cell populations or impair NK cell accumulation in lymph nodes
Figure S2 from Hbo1 Is a Cyclin E/CDK2 Substrate That Enriches Breast Cancer Stem-like Cells
Authors: Duong MyLinh T. , Akli Said , Macalou Sira , Biernacka Anna , Debeb Bisrat G. , Yi Min , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

Figure S2: CD44hi/CD24lo sorted cells are capable of generating non-CSCs.
Supplementary Methods, Figure Legends 1-4, Table Legend 1 from Superior Penetration and Retention Behavior of 50 nm Gold Nanoparticles in Tumors
Authors: Huo Shuaidong , Ma Huili , Huang Keyang , Liu Juan , Wei Tuo , Jin Shubin , Zhang Jinchao , He Shengtai , Liang Xing-Jie
Published: April 2023

PDF file - 42K, Methods including Bio-TEM observation of spheroids and tumors, ICP-MS, HE staining, Flow cytometry and ESEM observation of MCF-7 spheroids and monolayer cells
Supplementary Figure 4 from Superior Penetration and Retention Behavior of 50 nm Gold Nanoparticles in Tumors
Authors: Huo Shuaidong , Ma Huili , Huang Keyang , Liu Juan , Wei Tuo , Jin Shubin , Zhang Jinchao , He Shengtai , Liang Xing-Jie
Published: April 2023

PDF file - 69K, Images of tissues after HE staining, and the corresponding tissue's images taken under dark field
Supplementary Figure 3 from Superior Penetration and Retention Behavior of 50 nm Gold Nanoparticles in Tumors
Authors: Huo Shuaidong , Ma Huili , Huang Keyang , Liu Juan , Wei Tuo , Jin Shubin , Zhang Jinchao , He Shengtai , Liang Xing-Jie
Published: April 2023

PDF file - 22K, Cytotoxicity of MCF-7 monolayer cells after treated with 50 nm and 100 nm Au@tiopronin nanoparticles for 24 h
Supplementary Figures 1-5 and Tables 1-5 from Chromatin Regulator PRC2 Is a Key Regulator of Epigenetic Plasticity in Glioblastoma
Authors: Natsume Atsushi , Ito Motokazu , Katsushima Keisuke , Ohka Fumiharu , Hatanaka Akira , Shinjo Keiko , Sato Shinya , Takahashi Satoru , Ishikawa Yuta , Takeuchi Ichiro , Shimogawa Hiroki , Uesugi Motonari , Okano Hideyuki , Kim Seung U. , Wakabayashi Toshihiko , Issa Jean-Pierre J. , Sekido Yoshitaka , Kondo Yutaka
Published: April 2023

PDF - 157KB, Figure S1. Characterization of GSCs. Figure S2. Significance of EZH2/PRC2 in GBMs and GSCs. Figure S3. ChIP-chip analysis and MCAM analysis in GSCs. Figure S4. Effects of Wnt1-KD and BMP5-overexpression in GSCs. Figure S5. Downregulation of EZH2 abrogates tumorigenicity. Supplementary Table S1. Primer sequence data Supplementary Table S2. Tumorigenicity of GSCs and S-BTCs in the brain of NOD-SCID mice Supplementary Table S3. Validation of microarray analyses Supplementary Table S4. Targets of H3K27me3 in 1228-GSC, 1228-S-BTC, 0316-GSC, and 0316-S-BTC Supplementary Table S5. List of genes with commonly altered expression in 1228- and 0316-GSCs after serum exposure.
Supplementary Data Legends and Methods from Novel Oncogene–Induced Metastatic Prostate Cancer Cell Lines Define Human Prostate Cancer Progression Signatures
Authors: Ju Xiaoming , Ertel Adam , Casimiro Mathew C. , Yu Zuoren , Meng Hui , McCue Peter A. , Walters Rhonda , Fortina Paolo , Lisanti Michael P. , Pestell Richard G.
Published: April 2023

PDF file - 132KB, Legends for Supplementary Table 1 and Figures 1-7, and Supplementary Methods
Supplementary Figure 6 from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: April 2023

PDF file - 5301K, Supplemental Figure 6: Classification of human MB xenografts.
Supplementary Figure Legend from Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury
Authors: Zhan Yu , Chen Po-Ju , Sadler William D. , Wang Fuyuan , Poe Sara , Núñez Gabriel , Eaton Kathryn A. , Chen Grace Y.
Published: April 2023

PDF file - 98K
Supplementary Figure 5 from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: April 2023

PDF file - 2288K, Supplemental Figure 5: Aurk inhibitor blocks tumor growth in vivo.
Supplementary Figures from C1GALT1 Enhances Proliferation of Hepatocellular Carcinoma Cells via Modulating MET Glycosylation and Dimerization
Authors: Wu Yao-Ming , Liu Chiung-Hui , Huang Miao-Juei , Lai Hong-Shiee , Lee Po-Huang , Hu Rey-Heng , Huang Min-Chuan
Published: April 2023

PDF file, 119K, Supplementary Figure S1. Statistical analysis of C1GALT1 expression in tissue microarrays. Supplementary Figure S2. Immunofluorescence staining of C1GALT1 in HCC cells. Supplementary Figure S3. Effects of C1GALT1 on cell cycles. Supplementary Figure S4. Establishment of stable transfectants of C1GALT1 knockdown cells. Supplementary Figure S5. Expression of C1GALT1 in the xenografted tumors. Supplementary Figure S6. C1GALT1 regulates HGF-induced migration and invasion of HCC cells. Supplementary Figure S7. MET is decorated with short O-glycans.
Supplementary Figure 2 from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: April 2023

PDF file - 1674K, Supplemental Figure 2: Aurk and Plk inhibitors block proliferation of patched mutant tumor cells.
Supplementary Figure S1 from Extracellular DNA in Pancreatic Cancer Promotes Cell Invasion and Metastasis
Authors: Wen Fushi , Shen Alex , Choi Andrew , Gerner Eugene W. , Shi Jiaqi
Published: April 2023

PDF file - 170K, Apoptosis level is higher in HPDE Cells than in BxPc3 cells
Supplementary Figure Legends from Extracellular DNA in Pancreatic Cancer Promotes Cell Invasion and Metastasis
Authors: Wen Fushi , Shen Alex , Choi Andrew , Gerner Eugene W. , Shi Jiaqi
Published: April 2023

PDF file - 60K, Legend for Supplementary Figures S1-S5
Supplementary Figures from A Synthetic Lethality–Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1
Authors: Oike Takahiro , Ogiwara Hideaki , Tominaga Yuichi , Ito Kentaro , Ando Osamu , Tsuta Koji , Mizukami Tatsuji , Shimada Yoko , Isomura Hisanori , Komachi Mayumi , Furuta Koh , Watanabe Shun-Ichi , Nakano Takashi , Yokota Jun , Kohno Takashi
Published: April 2023

PDF file, 1764K, Supplementary Figure S1. Immunohistochemical staining for BRG1 and BRM in cancer cell lines. Supplementary Figure S2. E431* and E608* Supplementary Figure S3. Fluorescence in situ hybridization for the detection of FGFR1 amplification in a case of squamous lung cell carcinoma. Supplementary Figure S4. Immunoblot analysis of SWI/SNF and ACF chromatinremodeling proteins. Supplementary Figure S5. Survival of H1299 (BRG1-deficient) and HeLa (BRG1-proficient) cells after shRNA-mediated knockdown of BRM (shBRM). Supplementary Figure S6. The effects of BRM knockdown on the morphologies of BRG1-deficient and proficient cancer cells. Supplementary Figure S7. Effect of BRM knockdown on the induction of senescence in BRG1-deficient and -proficient non-small-cell lung carcinoma cells.
Supplementary Tables from Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
Authors: Arendt Lisa M. , McCready Jessica , Keller Patricia J. , Baker Dana D. , Naber Stephen P. , Seewaldt Victoria , Kuperwasser Charlotte
Published: April 2023

PDF file, 65K, Primers for quantitative Real-Time PCR (S1); Obesity-like stromal cells shorten the latency and increase the incidence of tumor development (S2).
Supplementary Figure 6 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: April 2023

PDF file - 416K, Figure S6. Trastuzumab/LJM716 combination inhibits 3D spheroid growth of breast cancer cell lines more effectively than trastuzumab/pertuzumab combination.
Supplementary Figure 4 from Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
Authors: Arendt Lisa M. , McCready Jessica , Keller Patricia J. , Baker Dana D. , Naber Stephen P. , Seewaldt Victoria , Kuperwasser Charlotte
Published: April 2023

PDF file, 322K, Obesity-like stromal cells did not increase responsiveness of endothelial cells.
Supplementary Figure 5 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: April 2023

PDF file - 237K, Figure S5. Combination treatment consisting of trastuzumab+LJM716 or Cetuximab+LJM716 is well tolerated.
Supplementary Figure 2 from Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
Authors: Arendt Lisa M. , McCready Jessica , Keller Patricia J. , Baker Dana D. , Naber Stephen P. , Seewaldt Victoria , Kuperwasser Charlotte
Published: April 2023

PDF file, 440K, Characterization of SVF cell lines and effects of treatment with diphtheria toxin in vivo.
Supplementary Figure 2 from DNA Methylation-Mediated Repression of miR-886-3p Predicts Poor Outcome of Human Small Cell Lung Cancer
Authors: Cao Jianzhong , Song Yongmei , Bi Nan , Shen Jie , Liu Wenyang , Fan Jing , Sun Guogui , Tong Tong , He Jie , Shi Yuankai , Zhang Xun , Lu Ning , He Yinghua , Zhang Hongyu , Ma Kelong , Luo Xiaoying , Lv Lei , Deng Hui , Cheng Jing , Zhu Jingde , Wang Luhua , Zhan Qimin
Published: April 2023

PDF file - 175K, Effects of the 5-Az'-deorcytidine treatment on NCI-H446 cells.
Supplementary Table 2 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer
Authors: Liu Yu-Peng , Liao Wen-Chi , Ger Luo-Ping , Chen Jiun-Chin , Hsu Tai-I , Lee Yu-Cheng , Chang Hong-Tai , Chen Yu-Chia , Jan Yi-Hua , Lee Kuen-Haur , Zeng Yu-Hao , Hsiao Michael , Lu Pei-Jung
Published: April 2023

PDF file, 63K, Association of CTMP expression with prognosis of patients with different cancer type in 4 cohorts from Prognoscan database.
Supplementary Table 1 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer
Authors: Liu Yu-Peng , Liao Wen-Chi , Ger Luo-Ping , Chen Jiun-Chin , Hsu Tai-I , Lee Yu-Cheng , Chang Hong-Tai , Chen Yu-Chia , Jan Yi-Hua , Lee Kuen-Haur , Zeng Yu-Hao , Hsiao Michael , Lu Pei-Jung
Published: April 2023

PDF file, 48K, Expression of CTMP in the tissue microarray comprised of different human cancer types.
Supplementary Table 1 from Intestinal Bacteria Modify Lymphoma Incidence and Latency by Affecting Systemic Inflammatory State, Oxidative Stress, and Leukocyte Genotoxicity
Authors: Yamamoto Mitsuko L. , Maier Irene , Dang Angeline Tilly , Berry David , Liu Jared , Ruegger Paul M. , Yang Jiue-in , Soto Phillip A. , Presley Laura L. , Reliene Ramune , Westbrook Aya M. , Wei Bo , Loy Alexander , Chang Christopher , Braun Jonathan , Borneman James , Schiestl Robert H.
Published: April 2023

PDF file - 369K, Reverse PCR primers used in the Illumina-based high throughput sequence analysis of bacterial rRNA genes.
Supplementary Figure 3 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer
Authors: Liu Yu-Peng , Liao Wen-Chi , Ger Luo-Ping , Chen Jiun-Chin , Hsu Tai-I , Lee Yu-Cheng , Chang Hong-Tai , Chen Yu-Chia , Jan Yi-Hua , Lee Kuen-Haur , Zeng Yu-Hao , Hsiao Michael , Lu Pei-Jung
Published: April 2023

PDF file, 187K, The N-terminal domain, 1-64 a.a., of CTMP is required, but not sufficient, to induce Akt phosphorylation, colony formation and cell proliferation.
Supplementary Figure 1 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer
Authors: Liu Yu-Peng , Liao Wen-Chi , Ger Luo-Ping , Chen Jiun-Chin , Hsu Tai-I , Lee Yu-Cheng , Chang Hong-Tai , Chen Yu-Chia , Jan Yi-Hua , Lee Kuen-Haur , Zeng Yu-Hao , Hsiao Michael , Lu Pei-Jung
Published: April 2023

PDF file, 75K, Overexpression of CTMP enhances PI3K-mediated Akt phosphorylation.
Supplementary Table 1 from Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer
Authors: Proffitt Kyle David , Madan Babita , Ke Zhiyuan , Pendharkar Vishal , Ding Lijun , Lee May Ann , Hannoush Rami N. , Virshup David M.
Published: April 2023

PDF file - 71KB, C59 does not significantly inhibit the proliferation of any of 46 tested cancer cell lines in vitro at concentrations that completely inhibit PORCN
Supplementary Table 2 from Characterization of Rearrangements Involving the ALK Gene Reveals a Novel Truncated Form Associated with Tumor Aggressiveness in Neuroblastoma
Authors: Cazes Alex , Louis-Brennetot Caroline , Mazot Pierre , Dingli Florent , Lombard Bérangère , Boeva Valentina , Daveau Romain , Cappo Julie , Combaret Valérie , Schleiermacher Gudrun , Jouannet Stéphanie , Ferrand Sandrine , Pierron Gaëlle , Barillot Emmanuel , Loew Damarys , Vigny Marc , Delattre Olivier , Janoueix-Lerosey Isabelle
Published: April 2023

PDF file - 163K, Information on rearrangements detected by capture and paired-end sequencing and validated by PCR
Supplementary Figures 1-4 from Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer
Authors: Proffitt Kyle David , Madan Babita , Ke Zhiyuan , Pendharkar Vishal , Ding Lijun , Lee May Ann , Hannoush Rami N. , Virshup David M.
Published: April 2023

PDF file - 730KB, 1, Uncut gels. 2, Tumor weights, toxicity and target genes of C59 in MMTV-WNT1 mice. 3, Effect on �-catenin by IHC. 4, Effect on tissues by H&E staining.
Supplementary Figure 3 from Characterization of Rearrangements Involving the ALK Gene Reveals a Novel Truncated Form Associated with Tumor Aggressiveness in Neuroblastoma
Authors: Cazes Alex , Louis-Brennetot Caroline , Mazot Pierre , Dingli Florent , Lombard Bérangère , Boeva Valentina , Daveau Romain , Cappo Julie , Combaret Valérie , Schleiermacher Gudrun , Jouannet Stéphanie , Ferrand Sandrine , Pierron Gaëlle , Barillot Emmanuel , Loew Damarys , Vigny Marc , Delattre Olivier , Janoueix-Lerosey Isabelle
Published: April 2023

PDF file - 110K, 2p amplicons in the CLB-Bar cell line
Supplementary Figure 2 from Characterization of Rearrangements Involving the ALK Gene Reveals a Novel Truncated Form Associated with Tumor Aggressiveness in Neuroblastoma
Authors: Cazes Alex , Louis-Brennetot Caroline , Mazot Pierre , Dingli Florent , Lombard Bérangère , Boeva Valentina , Daveau Romain , Cappo Julie , Combaret Valérie , Schleiermacher Gudrun , Jouannet Stéphanie , Ferrand Sandrine , Pierron Gaëlle , Barillot Emmanuel , Loew Damarys , Vigny Marc , Delattre Olivier , Janoueix-Lerosey Isabelle
Published: April 2023

PDF file - 115K, FISH analysis on the N206/Kelly cell line with various BAC probes
Supplementary Figure Legend from Combined Targeting of PDK1 and EGFR Triggers Regression of Glioblastoma by Reversing the Warburg Effect
Authors: Velpula Kiran Kumar , Bhasin Arnima , Asuthkar Swapna , Tsung Andrew J.
Published: April 2023

PDF file - 87K
Supplementary Figure Legend from Novel Therapeutic Strategy to Prevent Chemotherapy-Induced Persistent Sensory Neuropathy By TRPA1 Blockade
Authors: Trevisan Gabriela , Materazzi Serena , Fusi Camilla , Altomare Alessandra , Aldini Giancarlo , Lodovici Maura , Patacchini Riccardo , Geppetti Pierangelo , Nassini Romina
Published: April 2023

PDF File - 45K, Figure legend referred to Supplementary figure 1.
Supplementary Tables 1 through 6 from Downregulation of microRNA-515-5p by the Estrogen Receptor Modulates Sphingosine Kinase 1 and Breast Cancer Cell Proliferation
Authors: Pinho Filipa G. , Frampton Adam E. , Nunes Joao , Krell Jonathan , Alshaker Heba , Jacob Jimmy , Pellegrino Loredana , Roca-Alonso Laura , de Giorgio Alexander , Harding Victoria , Waxman Jonathan , Stebbing Justin , Pchejetski Dmitry , Castellano Leandro
Published: April 2023

PDF file, 150K, Table S1. Patient clinicopathological information (BC, breast cancer; IDC, invasive ductal carcinoma; IMC, invasive mixed carcinoma; ILC, invasive lobular carcinoma, ER, estrogen receptor; PgR, progesterone receptor; Her2, human epidermal growth factor receptor 2 respectively); Table S2. Primers used for the SK1 3' UTR amplification. ; Table S3. Details of the miR-515-5p promoter region cloning into the pGl2- basic plasmid. ; Table S4. Primers and their respective sequence. ; Table S5. Antibodies and their respective preparation. ; Table S6. Bibliographic references of the microRNAs predicted to target the SK1 3'UTR. ;
Supplementary Figure 5 from Downregulation of microRNA-515-5p by the Estrogen Receptor Modulates Sphingosine Kinase 1 and Breast Cancer Cell Proliferation
Authors: Pinho Filipa G. , Frampton Adam E. , Nunes Joao , Krell Jonathan , Alshaker Heba , Jacob Jimmy , Pellegrino Loredana , Roca-Alonso Laura , de Giorgio Alexander , Harding Victoria , Waxman Jonathan , Stebbing Justin , Pchejetski Dmitry , Castellano Leandro
Published: April 2023

PDF file, 2594K, Figure S5. miR-515-5p levels are confirmed to be up-regulated in ERalpha-negative breast tumors in an independent dataset. GEO2R analysis of miR-515-5p expression in ERalpha-negative, n=82 and ERalpha-positive, n=128 using the dataset GSE22220 (19). miR-515-3p expression was also analyzed as a control (ns, non-significant; ***P<0.001).
Supplementary Figure 2 from Production of Gastrointestinal Tumors in Mice by Modulating Latent TGF-β1 Activation
Authors: Shibahara Kotaro , Ota Mitsuhiko , Horiguchi Masahito , Yoshinaga Keiji , Melamed Jonathan , Rifkin Daniel B.
Published: April 2023

PDF file - 120K, Pathological Scores for WT, Itgb8-/-, Tgfb1C33S/C33S, Tgfb1C33S/C33S;Itgb8-/-, Tgfb1C33S/C33S and Tgfb1-/C33S Mice. A
Supplementary Table 1 from β-Catenin Signaling Is a Critical Event in ErbB2-Mediated Mammary Tumor Progression
Authors: Schade Babette , Lesurf Robert , Sanguin-Gendreau Virginie , Bui Tung , Deblois Geneviève , O'Toole Sandra A. , Millar Ewan K.A. , Zardawi Sara J. , Lopez-Knowles Elena , Sutherland Robert L. , Giguère Vincent , Kahn Michael , Hallett Michael , Muller William J.
Published: April 2023

PDF file - 1791K, List of Microarray data.
Supplementary Figure 2 from β-Catenin Signaling Is a Critical Event in ErbB2-Mediated Mammary Tumor Progression
Authors: Schade Babette , Lesurf Robert , Sanguin-Gendreau Virginie , Bui Tung , Deblois Geneviève , O'Toole Sandra A. , Millar Ewan K.A. , Zardawi Sara J. , Lopez-Knowles Elena , Sutherland Robert L. , Giguère Vincent , Kahn Michael , Hallett Michael , Muller William J.
Published: April 2023

PDF file - 102K, ErbB2KI mammary tumor cells exhibit co-expression of Krt8 and Krt5.
Supplementary Figure Legend from Inhibition of AMPK and Krebs Cycle Gene Expression Drives Metabolic Remodeling of Pten-Deficient Preneoplastic Thyroid Cells
Authors: Antico Arciuch Valeria G. , Russo Marika A. , Kang Kristy S. , Di Cristofano Antonio
Published: April 2023

PDF file - 45K
Supplementary Table 2 from Kinetic Modeling–Based Detection of Genetic Signatures That Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network
Authors: Vera Julio , Schmitz Ulf , Lai Xin , Engelmann David , Khan Faiz M. , Wolkenhauer Olaf , Pützer Brigitte M.
Published: April 2023

PDF file - 106K, Model definition and parameters
Supplementary Video 2 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
Authors: Pérez de Castro Ignacio , Aguirre-Portolés Cristina , Fernández-Miranda Gonzalo , Cañamero Marta , Cowley Dale O. , Van Dyke Terry , Malumbres Marcos
Published: April 2023

AVI file - 543KB, Time-lapse live imaging of H2B-EGFP-expressing, control MEFs undergoing normal cell cycle.
Supplementary Video 1 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
Authors: Pérez de Castro Ignacio , Aguirre-Portolés Cristina , Fernández-Miranda Gonzalo , Cañamero Marta , Cowley Dale O. , Van Dyke Terry , Malumbres Marcos
Published: April 2023

AVI file - 507KB, Time-lapse live imaging of H2B-EGFP-expressing, control MEFs undergoing normal cell cycle.
Supplementary Figure Legends from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
Authors: Pérez de Castro Ignacio , Aguirre-Portolés Cristina , Fernández-Miranda Gonzalo , Cañamero Marta , Cowley Dale O. , Van Dyke Terry , Malumbres Marcos
Published: April 2023

PDF file - 107KB
Supplementary Table 1 from MIG-7 Controls COX-2/PGE2-Mediated Lung Cancer Metastasis
Authors: Ho Ming-Yi , Liang Shu-Mei , Hung Shao-Wen , Liang Chi-Ming
Published: April 2023

PDF file - 64K, Sequences of primer pairs
Supplementary Figure 5 from PD-1–Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer
Authors: Badoual Cécile , Hans Stéphane , Merillon Nathalie , Van Ryswick Cordélia , Ravel Patrice , Benhamouda Nadine , Levionnois Emeline , Nizard Mevyn , Si-Mohamed Ali , Besnier Nicolas , Gey Alain , Rotem-Yehudar Rinat , Pere Hélène , Tran Thi , Guerin Coralie L. , Chauvat Anne , Dransart Estelle , Alanio Cécile , Albert Sebastien , Barry Beatrix , Sandoval Federico , Quintin-Colonna Françoise , Bruneval Patrick , Fridman Wolf H. , Lemoine Francois M. , Oudard Stephane , Johannes Ludger , Olive Daniel , Brasnu Daniel , Tartour Eric
Published: April 2023

PDF file - 4.8MB, Colocalization between PD1 positive cells and Foxp3- or Tim3- positive cells
Supplementary Figure 5 from Trop-2 Promotes Prostate Cancer Metastasis By Modulating β1 Integrin Functions
Authors: Trerotola Marco , Jernigan Danielle L. , Liu Qin , Siddiqui Javed , Fatatis Alessandro , Languino Lucia R.
Published: April 2023

PDF file - 1575K, Trop-2 co-localizes with α5 and β1 integrin subunits in trafficking vesicles.
Supplementary Figures from EGFR-Activating Mutations Correlate with a Fanconi Anemia–like Cellular Phenotype That Includes PARP Inhibitor Sensitivity
Authors: Pfäffle Heike N. , Wang Meng , Gheorghiu Liliana , Ferraiolo Natalie , Greninger Patricia , Borgmann Kerstin , Settleman Jeffrey , Benes Cyril H. , Sequist Lecia V. , Zou Lee , Willers Henning
Published: April 2023

PDF file, 1491K, Fig. S1-3 describe crosslinker sensitivity of EGFR mutant cells, Fig. S4 details a FANCD2/FAN1 defect in interstrand crosslink incision, Fig. S5-7 characterizes the homologous recombination phenotype of EGFR mutant cells, and Fig. S8 describes the olaparib sensitivity of EGFR mutant cells.
Supplementary Figures 1 - 7 from The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress
Authors: Sahm Felix , Oezen Iris , Opitz Christiane A. , Radlwimmer Bernhard , von Deimling Andreas , Ahrendt Tilman , Adams Seray , Bode Helge B. , Guillemin Gilles J. , Wick Wolfgang , Platten Michael
Published: April 2023

PDF file - 164K, Supplemental Figure 1: IDO-1 expression in glioma tissue sections. Supplemental Figure 2: Viability determined by MTT assay in T325 primary glioma cells (a) and HA1800 primary astrocytes (b). Supplemental Figure 3: NAD+ levels in malignant glioma cells A172 and human astrocytes after application of FK866, A172 P=0.006, astrocytes P=0.002 (a). NAD+ levels in A172 glioma cells treated with TMZ, P=0.009 (b). NAD+ levels in A172 cells treated with FK866 and supplemented with QA (c). Supplemental Figure 4: NAPRT expression in normal brain and glioma tissue WHO grade IIIV (28), P=0.86. Supplemental Figure 5: Immunoblot of QPRT in shQPRT and control A172 cells (a). CD68/3-HAO co-expression in tissue sections of glioblastoma (b). Test for CD14 expression in A172 and human astrocytes (c), QPRT expression in additional primary cells (c). Supplemental Figure 6: Survival analysis of glioblastoma patients with tumors expressing high or low levels of QPRT (28). Supplemental Figure 7: Detection of QA and picolinic acid (PA) via GC/MS in supernatant of microglia, glioma cells lines, human astrocytes and glioma-initiating cells T325.
Supplementary Figure Legend, Table 1 from The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress
Authors: Sahm Felix , Oezen Iris , Opitz Christiane A. , Radlwimmer Bernhard , von Deimling Andreas , Ahrendt Tilman , Adams Seray , Bode Helge B. , Guillemin Gilles J. , Wick Wolfgang , Platten Michael
Published: April 2023

PDF file - 100K, Subtype, age, gender and time to recurrence (where applicable for this study) of glioblastoma patients. GBM - glioblastoma; m - male; f - female.
Supplementary Figure 5 from c-Src Modulates Estrogen-Induced Stress and Apoptosis in Estrogen-Deprived Breast Cancer Cells
Authors: Fan Ping , Griffith Obi L. , Agboke Fadeke A. , Anur Pavana , Zou Xiaojun , McDaniel Russell E. , Creswell Karen , Kim Sung Hoon , Katzenellenbogen John A. , Gray Joe W. , Jordan V. Craig
Published: April 2023

PDF file - 47K, 5A, The oxidative stress indicator HMOX1 expressed in wild-type MCF-7 cells after E2 treatment. Wild-type MCF-7 cells were cultured in E2 free medium for three days. Then, cells were plated in six-well plates. After one day, cells were treated with vehicle (0.1% EtOH) and E2 (10-9 mol/L) for different time points as indicated and the cells were harvested in TRIzol for real-time PCR. P<0.001, ** compared with control. 5B, The oxidative stress indicator HMOX1 expressed in long-term E2 deprived MCF-7:2A cells after E2 treatment. MCF-7:2A cells were plated in six-well plates. After one day, cells were treated with vehicle (0.1% EtOH) and E2 (10-9 mol/L) for different time points as indicated and the cells were harvested in TRIzol for real-time PCR. P<0.05, * compared with control. 5C, The oxidative stress indicator HMOX1 expressed in long-term E2 deprived MCF-7:5C cells after E2 treatment. MCF-7:5C cells were plated in six-well plates. After one day, cells were treated with vehicle (0.1% EtOH) and E2 (10-9 mol/L) for different time points as indicated and the cells were harvested in TRIzol for real-time PCR. P<0.05, * compared with control. P<0.001, ** compared with control.
Supplementary Figures 1 - 8 from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology
Authors: Abaan Ogan D. , Polley Eric C. , Davis Sean R. , Zhu Yuelin J. , Bilke Sven , Walker Robert L. , Pineda Marbin , Gindin Yevgeniy , Jiang Yuan , Reinhold William C. , Holbeck Susan L. , Simon Richard M. , Doroshow James H. , Pommier Yves , Meltzer Paul S.
Published: April 2023

PDF file - 3388K, Supplementary Figure 1: Variant filtering decision tree. Supplementary Figure 2: Distribution of variants by annotation. Supplementary Figure 3: The NCI-60 cell lines. Supplementary Figure 4: Distribution of variants by type. Supplementary Figure 5: Phylogenic conservation of POL epsilon-P286. Supplementary Figure 6: A snapshot of the WES dataset in Variant Analysis by Ingenuity Systems (http://www.ingenuity.com/NCI60_WES). Supplementary Figure 7: Pattern comparison for cell with wild-type TP53 status. Supplementary Figure 8: Receiver operating curves (ROC) for cross-validated drug predictors.
Supplementary Table 1 from Nitric Oxide Production Upregulates Wnt/β-Catenin Signaling by Inhibiting Dickkopf-1
Authors: Du Qiang , Zhang Xinglu , Liu Quan , Zhang Xianghong , Bartels Christian E. , Geller David A.
Published: April 2023

PDF file - 64K, Tumor samples summary.
Supplementary Figure Legends 1-2 from A Classification Model for BRCA2 DNA Binding Domain Missense Variants Based on Homology-Directed Repair Activity
Authors: Guidugli Lucia , Pankratz Vernon S. , Singh Namit , Thompson James , Erding Catherine A. , Engel Christoph , Schmutzler Rita , Domchek Susan , Nathanson Katherine , Radice Paolo , Singer Christian , Tonin Patricia N. , Lindor Noralane M. , Goldgar David E. , Couch Fergus J.
Published: April 2023

PDF file - 42K
Supplementary Figure 1 from miR-186 Downregulation Correlates with Poor Survival in Lung Adenocarcinoma, Where It Interferes with Cell-Cycle Regulation
Authors: Cai Junchao , Wu Jueheng , Zhang Huizhong , Fang Lishan , Huang Yongbo , Yang Yi , Zhu Xun , Li Rong , Li Mengfeng
Published: April 2023

PDF file - 23K, Real-time analysis of miR-186 expression in A549 and SK-MES-1 cells transduced with control vector or miR-186
Supplementary Figure 5 from A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis
Authors: Sheltzer Jason M.
Published: April 2023

PDF file - 213K, The TRI70 and CIN70 gene sets, but not the HET70 gene set, sort human tissues according to their level of PCNA expression.
Supplementary Figure 4 from A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis
Authors: Sheltzer Jason M.
Published: April 2023

PDF file - 162K, The CIN70 gene signature is correlated with proliferation rates and anti-correlated with karyotype heterogeneity.
Supplementary Figure 3 from Angiopoietin-2 Functions as a Tie2 Agonist in Tumor Models, Where It Limits the Effects of VEGF Inhibition
Authors: Daly Christopher , Eichten Alexandra , Castanaro Carla , Pasnikowski Elizabeth , Adler Alexander , Lalani Alshad S. , Papadopoulos Nicholas , Kyle Alastair H. , Minchinton Andrew I. , Yancopoulos George D. , Thurston Gavin
Published: April 2023

PDF file - 165K, Images of whole tumor sections demonstrating the dramatic effect of REGN910 + ZALTRAP� combination treatment on tumor cell death
Supplementary Figures 1 - 9 from ETS Transcription Factor ESE1/ELF3 Orchestrates a Positive Feedback Loop That Constitutively Activates NF-κB and Drives Prostate Cancer Progression
Authors: Longoni Nicole , Sarti Manuela , Albino Domenico , Civenni Gianluca , Malek Anastasia , Ortelli Erica , Pinton Sandra , Mello-Grand Maurizia , Ostano Paola , D'Ambrosio Gioacchino , Sessa Fausto , Garcia-Escudero Ramon , Thalmann George N. , Chiorino Giovanna , Catapano Carlo V. , Carbone Giuseppina M.
Published: April 2023

PDF file - 782K, ESE1/ELF3 overexpression in primary prostate tumors (S1); Generation of stable ESE-1/ELF3 over-expressing prostate cancer cell lines (S2); Level of ESE1/ELF3 in prostate tumor xenografts (S3); Network interactions between ESE1/ELF3-induced genes and ETS transcription factors (S4); Position of ETS binding sites identified by computational analysis using Motiviz (S5); Convergence between the transcriptional program induced in IL-1B transgenic mice and ESE1/ELF3 overexpressing 22RVI cells (S6); Reciprocal regulatory loops between ESE1/ELF3 and NFKB (S7); Immunofluorescence microscopy for detection of ESE1/ELF3, p50, p65, and nuclei (S8); Kaplan-Meyer analysis of overall survival of prostate cancer patients from the TMA cohort subdivided according to ESE1/ELF3 and p50/p65 nuclear expression (S9).
Supplementary Methods from Rb1 Haploinsufficiency Promotes Telomere Attrition and Radiation-Induced Genomic Instability
Authors: Gonzalez-Vasconcellos Iria , Anastasov Natasa , Sanli-Bonazzi Bahar , Klymenko Olena , Atkinson Michael J. , Rosemann Michael
Published: April 2023

PDF file - 103K, Includes list of primers used in this study. Also includes statistical analysis and gene expression assay.
Supplementary Methods from Tid1-L Inhibits EGFR Signaling in Lung Adenocarcinoma by Enhancing EGFR Ubiquitinylation and Degradation
Authors: Chen Chi-Yuan , Jan Chia-Ing , Lo Jeng-Fan , Yang Shuenn-Chen , Chang Yih-Leong , Pan Szu-Hua , Wang Wen-Lung , Hong Tse-Ming , Yang Pan-Chyr
Published: April 2023

PDF file - 187K, Additional methods including antibodies, oligonucleotides, reagents, plasmid and lentiviral constructs, and transfection/preparation of lentivirus particles, are described.
Supplementary Tables 4-7 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Link for Supplementary Tables 4-7 � PDF file 39K, Table 4 - Patient Clinical Treatment Response; Table 5 - Frequency of Lung Metastasis in Xenograft Lines; Table 6 - Sequenom Analysis of SNPS in Xenografts; Table 7 - Xenograft Short Tandem Repeat (STR) Profile
Supplementary Figure 2 from Tid1-L Inhibits EGFR Signaling in Lung Adenocarcinoma by Enhancing EGFR Ubiquitinylation and Degradation
Authors: Chen Chi-Yuan , Jan Chia-Ing , Lo Jeng-Fan , Yang Shuenn-Chen , Chang Yih-Leong , Pan Szu-Hua , Wang Wen-Lung , Hong Tse-Ming , Yang Pan-Chyr
Published: April 2023

PDF file - 201K, Computerized image analysis for IHC scoring.
Supplementary Figure 1 from Tid1-L Inhibits EGFR Signaling in Lung Adenocarcinoma by Enhancing EGFR Ubiquitinylation and Degradation
Authors: Chen Chi-Yuan , Jan Chia-Ing , Lo Jeng-Fan , Yang Shuenn-Chen , Chang Yih-Leong , Pan Szu-Hua , Wang Wen-Lung , Hong Tse-Ming , Yang Pan-Chyr
Published: April 2023

PDF file - 430K, Tid1-L/S expression in lung adenocarcinoma tissues and cells.
Supplementary Table 3 from Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics
Authors: Luo Ming , Zhao Xiaofeng , Chen Song , Liu Suling , Wicha Max S. , Guan Jun-Lin
Published: April 2023

PDF file, 68K, Outgrowth of basal and luminal MaECs from Ctrl-GFP, MFCKO-GFP and MFCKD-GFP mice.
Supplementary Table 1 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Supplementary Table 1 � XLXS file 41K, Patient characteristics by transplant generation
Supplementary Fig 4 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Supplementary Fig 4 � PDF file 123K, Treatment response concordance with the tumor of origin
Supplementary Figure 4 from Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics
Authors: Luo Ming , Zhao Xiaofeng , Chen Song , Liu Suling , Wicha Max S. , Guan Jun-Lin
Published: April 2023

PDF file, 624K, PyMT-induced tumor cells have a luminal cellular origin and FAK inhibitor treatment does not induce significant apoptosis in SUM149 and SUM159 breast cancer cells.
Supplementary Fig 1 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Supplementary Fig 1 � PDF file 42K, General design of the xenografting program
Supplementary Figure Legends from eIF4B Phosphorylation by Pim Kinases Plays a Critical Role in Cellular Transformation by Abl Oncogenes
Authors: Yang Jianling , Wang Jun , Chen Ke , Guo Guijie , Xi Ruijiao , Rothman Paul B. , Whitten Douglas , Zhang Lianfeng , Huang Shile , Chen Ji-Long
Published: April 2023

PDF - 32K, Legend for Supplementary Figures S1-S5.
Supplementary Figure 6 from Myeloid-Derived Suppressor Cells Function as Novel Osteoclast Progenitors Enhancing Bone Loss in Breast Cancer
Authors: Sawant Anandi , Deshane Jessy , Jules Joel , Lee Carnella M. , Harris Brittney A. , Feng Xu , Ponnazhagan Selvarangan
Published: April 2023

PDF file - 108K, In vivo bone destruction mediated by MDSC requires NO production
Supplementary Figure 5 from eIF4B Phosphorylation by Pim Kinases Plays a Critical Role in Cellular Transformation by Abl Oncogenes
Authors: Yang Jianling , Wang Jun , Chen Ke , Guo Guijie , Xi Ruijiao , Rothman Paul B. , Whitten Douglas , Zhang Lianfeng , Huang Shile , Chen Ji-Long
Published: April 2023

PDF - 50K, Generation of eIF4B-knockdown transgenic mice and retroviral or lentiviral vectors used in Abl-mediated bone marrow transformation, and model of eIF4B phosphorylation and function in Abl transformants.
Supplementary Figure 4 from Myeloid-Derived Suppressor Cells Function as Novel Osteoclast Progenitors Enhancing Bone Loss in Breast Cancer
Authors: Sawant Anandi , Deshane Jessy , Jules Joel , Lee Carnella M. , Harris Brittney A. , Feng Xu , Ponnazhagan Selvarangan
Published: April 2023

PDF file - 358K, MDSC(+bone mets), which become osteoclasts was the only population that had elevated NO levels
Supplementary Figure 3 from Myeloid-Derived Suppressor Cells Function as Novel Osteoclast Progenitors Enhancing Bone Loss in Breast Cancer
Authors: Sawant Anandi , Deshane Jessy , Jules Joel , Lee Carnella M. , Harris Brittney A. , Feng Xu , Ponnazhagan Selvarangan
Published: April 2023

PDF file - 100K, MDSC(+bone mets) did not express macrophage marker F4/80 during osteoclast differentiation and can induce bone destruction in vivo
Supplementary Figure 2 from eIF4B Phosphorylation by Pim Kinases Plays a Critical Role in Cellular Transformation by Abl Oncogenes
Authors: Yang Jianling , Wang Jun , Chen Ke , Guo Guijie , Xi Ruijiao , Rothman Paul B. , Whitten Douglas , Zhang Lianfeng , Huang Shile , Chen Ji-Long
Published: April 2023

PDF - 50K, Expression and phosphorylation of eIF4B exhibit an Abl kinases-dependent manner in v-Abl or Bcr-Abl transformants.
Supplementary Methods from Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway
Authors: Aggarwal Monika , Banerjee Taraswi , Sommers Joshua A. , Iannascoli Chiara , Pichierri Pietro , Shoemaker Robert H. , Brosh Robert M.
Published: April 2023

PDF file, 106K, Supplemental information regarding proteins, DNA substrates, immunofluorescence, cell cycle analysis by flow cytometry, and additional experimental procedures.
Supplementary Figure 5 from Novel DNA Damage Checkpoints Mediating Cell Death Induced by the NEDD8-Activating Enzyme Inhibitor MLN4924
Authors: Blank Jonathan L. , Liu Xiaozhen J. , Cosmopoulos Katherine , Bouck David C. , Garcia Khristofer , Bernard Hugues , Tayber Olga , Hather Greg , Liu Ray , Narayanan Usha , Milhollen Michael A. , Lightcap Eric S.
Published: April 2023

PDF file - 355K, Effect of Gene Knock-down on Cell Cycle Distribution of A375 Melanoma Cells in Combination with Vehicle
Supplementary Figure 2 from SOX10 Ablation Arrests Cell Cycle, Induces Senescence, and Suppresses Melanomagenesis
Authors: Cronin Julia C. , Watkins-Chow Dawn E. , Incao Art , Hasskamp Joanne H. , Schönewolf Nicola , Aoude Lauren G. , Hayward Nicholas K. , Bastian Boris C. , Dummer Reinhard , Loftus Stacie K. , Pavan William J.
Published: April 2023

PDF file, 152K, Loss of SOX10 expression does not consistently result in changes in protein levels of Cyclin/CDK proteins responsible for RB phosphorylation in early G1 phase.
Supplementary Figure 1 from SOX10 Ablation Arrests Cell Cycle, Induces Senescence, and Suppresses Melanomagenesis
Authors: Cronin Julia C. , Watkins-Chow Dawn E. , Incao Art , Hasskamp Joanne H. , Schönewolf Nicola , Aoude Lauren G. , Hayward Nicholas K. , Bastian Boris C. , Dummer Reinhard , Loftus Stacie K. , Pavan William J.
Published: April 2023

PDF file, 122K, Senescence associated heterochromatin foci (SAHF) are more pronounced in melanoma cells when SOX10shRNA is expressed compared to non-silencing (NS) control.
Supplementary Table 1 from FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer
Authors: Liu Rui , Li Jingyi , Xie Ke , Zhang Tao , Lei Yunlong , Chen Yi , Zhang Lu , Huang Kai , Wang Kui , Wu Hong , Wu Min , Nice Edouard C. , Huang Canhua , Wei Yuquan
Published: April 2023

PDF file, 80K, Differentially expressed proteins identified by 2-DE and MS/MS Analysis.
Supplementary Figure 5 from FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer
Authors: Liu Rui , Li Jingyi , Xie Ke , Zhang Tao , Lei Yunlong , Chen Yi , Zhang Lu , Huang Kai , Wang Kui , Wu Hong , Wu Min , Nice Edouard C. , Huang Canhua , Wei Yuquan
Published: April 2023

PDF file, 1695K, FGFR4 cooperates with Wnt signaling and CCL2/CCR2 axis to mediate TAF-induced EMT.
Supplementary Table 2 from Comparative Expression Analysis Reveals Lineage Relationships between Human and Murine Gliomas and a Dominance of Glial Signatures during Tumor Propagation In Vitro
Authors: Henriquez Nico V. , Forshew Tim , Tatevossian Ruth , Ellis Matthew , Richard-Loendt Angela , Rogers Hazel , Jacques Thomas S. , Reitboeck Pablo Garcia , Pearce Kerra , Sheer Denise , Grundy Richard G. , Brandner Sebastian
Published: April 2023

XLSX file, 381K, PNET specific genes.
Supplementary Figure 4 from FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer
Authors: Liu Rui , Li Jingyi , Xie Ke , Zhang Tao , Lei Yunlong , Chen Yi , Zhang Lu , Huang Kai , Wang Kui , Wu Hong , Wu Min , Nice Edouard C. , Huang Canhua , Wei Yuquan
Published: April 2023

PDF file, 1712K, Up-regulation of FGFR4 is required for TAF-induced aggressive phenotype of colorectal cancer cells.
Supplementary Figure 5 from Comparative Expression Analysis Reveals Lineage Relationships between Human and Murine Gliomas and a Dominance of Glial Signatures during Tumor Propagation In Vitro
Authors: Henriquez Nico V. , Forshew Tim , Tatevossian Ruth , Ellis Matthew , Richard-Loendt Angela , Rogers Hazel , Jacques Thomas S. , Reitboeck Pablo Garcia , Pearce Kerra , Sheer Denise , Grundy Richard G. , Brandner Sebastian
Published: April 2023

PDF file, 1105K, Derivation and testing of a human oligodendroglial gene signature.