bluuebunny/crossref_metadata_2025 huggingface dataset:
Desarrollo de recursos didácticos con el uso de las Tecnologías de la información y comunicación disponibles en una plataforma virtual
Authors: Del Carmen-Morales Yucels Anaí , Del Carmen-Morales Heidi , Felipe-Redondo Ana María , Hernández-Bautista Anayeli
Published: September 2020

Develop didactic resources with the use of ICT’S (Information Communication Tecnologies) to strengthen mathematics teaching with students of the Technological University of Huasteca Hidalguense it was the purpose of this study. The results of the diagnostic evaluation applied to a sample of 856 new students indicate that the performance is regular (6.1 points) in Arithmetic and insufficient (4.4) in Algebra (UTHH Academy of Mathematics, 2018); shows the following problems: failing rates, dropping out, mathematical fear calculations and problems solving related to their field of application, so that proposes the development of teaching resources available on an accessible platform. According to (CONOCER, 2016) the learning resources are instruments used in the educational context through their manipulation, observation, or reading, opportunities to learn are offered or with their use they intervene in the development of some teaching function; (Spiegel, 2006), It indicates they are necessary to promote the autonomy of students, future workers in the profile we teach. This work is based on the Methodology for the development of educational applications in multimedia environments (Bianchini, 1992) with the phases: a) Research and Analysis; b) Logical, functional and physical design; c) development; d) Implementation and production. As a result, educational resources were obtained (videos, infographics and digital evaluations) these support the teaching-learning process through organized information that complements, expands and details solution processes for teachers and students available on an institutional virtual platform.
ZonaTIC: Sitio web para la divulgación de la ciencia de las TIC en pro de la inclusión digital
Authors: Trejo-Cuevas Apolinar , Parra-Rodríguez Gerardo , Díaz-Robledo María Teresa , Torres-Yáñez Javier Jesús
Published: September 2020

Objective. Implement a website that allows the outreach of the science of Information and Communication Technologies to the staff of the university community of the UTNG to facilitate digital inclusion, taking advantage of the current infrastructure that the university has, as well as its human capital. Methodology. The adopted development model was a concurrent model: For the Frontend development the spiral model was used, which facilitates its design through the stages of prototyping, analysis and design. On the other hand, for the development of the Backend, the waterfall model was used, given the nature of the project, where the requirements are pre-established and with few changes. The phases of this model are: (Requirements. Survey of requirements, Design. Development of the database and class diagrams, Implementation Coding, Check. Tests, Maintenance. Correct errors in functionality) Contribution. Implementation of project-based learning (PBL) as a motivational teaching strategy in the development of web applications. Use of robust development tools used today by software factories, such as: Java, Spring, HTML5, CSS3, and Apache Maven; all this under a Model View Controller architecture.
Usos y abusos del celular en adolescentes
Authors: Ku-Ortiz Analuisa , Aguilar-Morales Norma
Published: September 2020

Since the beginning of the 21st century, the cell phone has become an essential element for daily life because thanks to its various functions, applications and updates, they have made our day-to-day activities become simple to carry out, since carry out an agenda, until you find information quickly saving a trip to the nearest library. This article has as main objective to expose the uses, whether personal or academic, of the cell phone, how this can give way to excessive abuse of the same and the consequences that can cause the abuse of it, of which there is excessive dependence on said device, causing anxiety and / or despair when performing tasks or when the cell phone is not at hand. In Zacatecas, Mexico, it has been proven that 80% of car accidents are caused by using the cell phone while driving a car, thus displacing the use of alcohol and other massive substances for health, in addition, it is proven that Talking on a mobile phone when driving, increases the chances of causing a road accident up to five times and absorbs from eight to thirteen seconds of distraction on average answers a call or writes a message through the cell phone. In conclusion, the use of the cell phone has benefits, both personal and academic or work, although it is also important to instill road education in adolescents, from home and even in the same institutions that are more likely to be victims of an accident to Cause of excessive cell phone abuse.
El impacto de las redes sociales en el proceso de enseñanza aprendizaje de la termodinámica
Authors: Rangel-Romero Carlos , Rojas-Garnica Juan Carlos , Moreno-Guzmán Javier Andrey , Hernández-Lazcano Ricardo
Published: September 2020

The development and use of social networks in the teaching-learning process that students develop, makes it an important and almost essential tool in the educational process. This entails changes, of various absolutely inevitable characteristics when it comes to launching innovative proposals in the teaching of thermodynamics. Hence the training processes in universities demand new models of pedagogical strategy capable of responding to the needs of the new society. However, in practice, during the teaching process of thermodynamics, it has been detected that traditionalist teaching approaches are still assumed, which does not meet the expectations demanded by the new training models. The research carried out is aimed at studying the evaluation of the teaching-learning process in its formative and meaningful training, with the objective of promoting formative evaluation through the use of virtual training environments.
El análisis de los elementos culturales como influencia de generación de conocimiento en las organizaciones agrícolas del Valle del Yaqui
Authors: Flores-López José Guadalupe , Ochoa-Jiménez Sergio
Published: September 2020

Agriculture in Mexico is a relatively small sector since it represented around 4% of the Gross Domestic Product (INEGI, 2009). However, the generation of employment is relatively greater, representing some 3.3 million farmers and 4.6 million wage and unpaid family workers. The purpose of the research is to analyze the influence of cultural factors in the generation of knowledge of the agricultural organizations of the Yaqui Valley for the construction of a theoretical model that describes a reality. For this, a mixed methodology was applied, for the quantitative study a questionnaire of 28 Likert scale items was designed, five points, which was applied to 90 agricultural organizations of the Yaqui Valley. For the qualitative study, a semi-structured interview was designed which was applied to seven leaders of agricultural associations and local producers. As a result, it was obtained that cultural factors influence the generation of knowledge by 20%, a low influence is estimated, and it is verified with qualitative results, which show that cultural elements such as tradition, customs and values are aspects that hamper the generation of new knowledge in the Yaqui Valley.
Imagen fílmica y narración. Análisis cinematográfico de Sensatez y sentimientos (Ang Lee, 1995)
Authors: López-Martínez Maria Teresa
Published: September 2020

The film Sense and Sensibility of Ang Lee (USA, 1995) narrates one of the literary works of the British writer Jane Austen (1775-1817), who is not only most famous for writing under the domain of drama and romance genres (Bergan, 2011), but specifically has written about women in 19th-century England facing problems related to their social position and relations. We wonder the following: “how the sensibility and senses in the Victorian Era is materialized in the narrative of Ang Lee (1995)?” Therefore, this film study will investigate how the roles of cinematographic language (Martin, 2002) and elements of narrative analysis (Casetti y Di Chio, 2003); (Stam, 2014) are used in scenes and/or sequences (Aumont y Marie, 2009). Our purpose is to further understanding how feelings like sense and sensibility (Sellés, 2010) are materialized through three aspects in the film: the characters and the narrative language of the cinema (Aumont y Marie, 2009).
Las características de los Dinki´s: factores de hedonismo y utilitarismo influyentes en el comportamiento de consumo
Authors: Sánchez-Figueroa Cruz Osbaldo
Published: September 2020

Objective The purpose of the following investigation is to determine the hedonistic and utilitarian characteristics of the Dinki and the relationship with the consumption behavior. Methodology The methodological design was quantitative, exploratory and descriptive studying the Dinki´s lifestyle, from the instrument the degree of hedonism and utilitarianism was studied, performed on 224 individuals with the characteristics of Dinkis (Double income, no children), in the municipalities of Colima and Villa de Álvarez. The instrument consisted of a survey with a semantic differential scale, which evaluates two opposite adjectives to identify hedonism and utilitarianism (Batra and Ahtola, 1991) composed of five statements with four items for hedonism and four items for utilitarianism. The validity was analyzed to determine its consistency using the SPSS statistical program, the quality was considered adequate, the scale had a Cronbach's alpha of α = 0.932. Contribution. A model is proposed to show the relationship of the variables, as well as the data obtained that determine the hedonistic or utilitarian characteristics and their relationship with their purchasing behavior, using a Principal Components Analysis and a regression.
Perfil del alumno de la Universidad Tecnológica del Norte de Aguascalientes
Authors: Delgado-Ruiz-Esparza Virginia , García-Rodríguez Juan Carlos
Published: September 2020

For the attention and follow-up of the student it is important to have information that allows carrying out actions with opportunity in their educational trajectory, with a view to the permanence and conclusion of their professional training. In turn, that the follow-up task by the tutor is oriented based on information from the student regarding their academic, socioeconomic and personal conditions that set the guideline for the tutorial function. Derived from the above, the objective is to characterize the student of the Technological University of the North of Aguascalientes, identifying their conditions of vulnerability that derive in a profile of the student, through the initial questionnaire of the newly admitted student of the September-December 2018 period of the TSU level. The student's diagnostic instrument, structured in three aspects, allows to identify conditions of vulnerability of academic, socioeconomic and / or psychological type, conditions that trigger an important part of the tutorial function. Having a profile represents an input for the preparation of the Tutorial Action Plan by the tutors and affects the lines of action in the Institutional Tutoring Program.
La gestión de la calidad mediante métodos científicos
Authors: Gutiérrez-García Alfredo
Published: September 2020

There are several tools for managing the quality of processes and services, which have as their common purpose to have an impact on customer satisfaction. In this sense, the appropriate procedure is to first identify quality critics (CTQs), a In order to focus the efforts on what is most important and apply QFD., secondarily in order to brainstorm, formulate a Forrester diagram simulating the repercussion that the variables cause in the loop or critic of greater importance obtained in the QFD to begin with scientific research and use statistical and control models that fit the root of the problem encountered.
Telesecundaria: entre la teoría y la práctica
Authors: Ochoa-Vargas Margarita , Chávez-López María Margarita
Published: September 2020

This study arises from the need to know the main conflicts of teaching practices in regular educators as teachers in training of the Telesecundaria modality within the state of Colima, to allow the development of a project that contributes to the improvement of these and contributes to the achievement of student learning. It is ethnographic, the key informants corresponded to eighth semester students of the Bachelor's degree in High School with a specialty in Telesecundaria of the normal state, as well as active teachers of the different school zones, to systematize the techniques proposed by Martínez Migueles were used. It was found that the challenges they face in their practice is to identify the point of balance between the theory and practice of the model that involves telesecundaria, the adaptation of the curriculum and television programs to the real needs of the students, effective leadership on the part of directors and supervisors who are aware of the reality of the classrooms as well as the characteristics of each school community. Finally, the need to revalue the education and practice of the telesecundaria teacher.
Método Delphi: validar un instrumento para la medición de características de un libro de texto de probabilidad y estadística
Authors: Martínez-Acosta María Teresa , Sánchez-Luján Bertha Ivonne , Camacho-Rios Alberto
Published: September 2020

The design and validity obtained from a data collection instrument are necessary to guarantee the reliability of the information within an investigation. This work describes several tools for measuring textbook contents, their particularities, and benefits indicated by different authors, the permanence of the book as a teaching resource within the classroom, in the life of the teacher and the student. As well as explaining how the subject of Probability and Statistics is taught in engineering careers at a higher level of education. The application of the Delphi Method allows developing a tool to measure the content of Probability and Statistics textbooks, employing ten proposed items. The usefulness of the methodology is demonstrated by ensuring the reliability of the tool, obtaining quantitative and qualitative information. The method is developed in stages for better understanding, and expert judgement is used, despite sometimes being ignored. Finally, an alternative validation in instrument design is proposed analytically and reliably.
Estructura de planeación orientada a fortalecer el trabajo de los cuerpos académicos de una facultad de ingeniería
Authors: Dimas-Rangel María Isabel , Torres-Bugdud Arturo , Palomares-Ruiz María Blanca Elizabeth , Sordia-Salinas César
Published: September 2020

The commitment that the Higher Education Institution in Mexico has with the country is important, since its contribution in the formation of quality professionals is a transcendent factor that impacts society. Considering the foregoing, this research work reflects on the importance of strengthening collegial work for the benefit of engineering Educational Programs, in order to favor engineering education through the work developed by academic experts in related educational areas. Due to the need to promote the research development of the teaching staff, the strengthening of the teacher's profile is promoted through strategies that motivate him to develop other activities that favor his professional development and have a positive impact on the students. The strategic basis of the proposal presented here is to promote, in a systemic manner, an administrative planning structure that integrates the factors that are important for strengthening the collaborative work of teachers, which makes it possible to visualize the development trajectory that members of a collegiate body may have. This planning was designed on the basis of a documentary analysis, it is implemented through the systemic-structural method, it is analyzed using descriptive statistics and it is improved through analysis of the results obtained. The systematization of these strategies of academic-administrative management favor in the evolution of these work teams, increasing in 57% the amount of Consolidated Academic Bodies and in 64% of Academic Bodies in Consolidation, which contributes in the strengthening of the Academic Capacity of the Faculty of Engineering, and positively impacting in integral formation of the future engineers.
Género, interés y elección de carreras en ciencia, tecnología, ingeniería y matemáticas: revisión de literatura
Authors: Vázquez-Reyes Estrella , Aguilar-Morales Norma
Published: September 2020

The shortage of human resources specialized in science, technology, engineering and technology (CTIM) throughout the world is a latent problem, coupled with the phenomenon of underrepresentation of women in these fields. Therefore, the purpose of this literature review is to analyze in the existing studies the factors that influence the interest in the choice of CTIM careers and their interrelation with gender. For this, a search was conducted in the databases of SCOPUS, Thompson, Elsevier and Redalyc, empirical articles of quantitative studies were included. It is found that the most studied variables are the influence of the family, the teachers, and the experiences of the subjects during middle and high school, self-efficacy, student peers and the expectations of the labor field. Gender stereotypes and roles have been poorly addressed, one of the limitations in this line of research is the insufficiency of longitudinal studies.
Apoyo educativo y de pares en las disciplinas en ciencia, tecnología, informática y matemáticas
Authors: Jiménez-León Rodolfo , Magaña-Medina Deneb Elí , Cisneros-Cohernour Edith , Aquino-Zúñiga Silvia Patricia
Published: September 2020

Objectives: There are few studies, which identify the support received by high school students in the decision making process for careers in science, technology, engineering and mathematics. The objective of the present study is to know the narratives of the students according to their interactions within their social and school environment, understanding the individual interest of the student in terms of mastery, tastes, participation, curiosity and attachment to the areas. Methodology: A focus group session was held with students of the mathematics career. From three trigger questions that assessed a total of 10 dimensions in the group, which allowed adjusting and enriching the theoretical structure through the synthetic analytical method to discover relationships and general characteristics. Contribution: The areas of interaction between friends within social roles and tutoring by teachers in the school context, are activities that strengthened decision making for people who participated in the focus group. Specific dimensions are defined for the intervention for the benefit of social inclusion in disadvantaged communities within the disciplines C.T.I.M. should be taken into account, especially by specialists in these areas.
Análisis sobre las aspiraciones educativas de los jóvenes de bachillerato
Authors: SESENTO Leticia , LUCIO Rodolfo
Published: September 2020

In this article we study the academic aspirations of the students and their relationship with the academic level of their parents. The total number of subjects was 377 young people of upper secondary level. The study was carried out in a quantitative approach with a descriptive, non-experimental and cross-sectional scope. The Questionnaire for the Evaluation of Academic Goals (CEMA-II) was used. The results show that the main reason for the students to enter the high school level was to continue their professional studies 85%, followed by why I need to work 5% and 4.2% say that they did so because of pressure from their parents or guardians. Depending on the academic level of the parents, 27% indicate that their mother has a bachelor's degree, 15% master's degree, 2% doctorate, 25% upper secondary, 22% secondary and 6% primary. In correspondence with the father, they indicate that 26.5% have a bachelor's degree, 16% master's degree, 3% doctorate, 22% average superior, 18% secondary and primary 9%. It is important to work from the tutoring individual goals to guide students regarding their interests and motivations, in relation to the content in class is substantial to work with meaningful learning.
Propuesta didáctica para la comprensión, consolidación y aplicación de las principales técnicas de conteo en la resolución y comprobación de problemas de probabilidad
Authors: HERRERA-MIRANDA Miguel Apolonio , HERRERA-MIRANDA Israel , VILLAGÓMEZ-MÉNDEZ Juan , CASTILLO-MEDINA Jorge Antonio
Published: September 2020

The Teaching-Learning process is complex; First, the interest, and motivation of the student is important. In addition to the above, the social and cultural context can have a positive or negative influence on learning in the area of mathematics and particularly on the notions of probability. The present work presents a didactic proposal that is supported by the use of computational tools. The objective of this proposal is to improve the understanding and fixation of concepts of counting techniques through the use of visual and descriptive forms (appropriate tables and codifications). Real-life examples are presented, so that the student can build formal definitions that allow generalizations under mathematical rigor. For the design of the teaching strategy we rely on constructivist and learning theories under didactic situations. These teaching models have great educational potential because they encourage reflection and analysis. In this way the student acquires skills in the approach, resolution, interpretation and verification of probability problems. In a second stage it is expected to experiment with the application of this proposal in the classroom. In this way, difficulties in teaching-learning processes can be identified and innovative teaching strategies can be proposed.
Desarrollo de herramientas para favorecer el aprendizaje del inglés
Authors: CRUZ-LOERA María de la Luz , MONTECILLO-PUENTE Francisco Javier , LÓPEZ-ENRIQUEZ Renato
Published: September 2020

The objective of this work is the creation of tools for learning the English language using augmented reality and humanoid robots, in order to interact with people autonomously in the learning process. For this, the contents of the English language programs and programs at the higher level were reviewed, language area heads and teachers were interviewed, in order to finish cable issues in language learning. At present, having a second language in the field of education today is considered a necessity. Currently, higher level institutions use English language learning techniques based on books, flash-cards, slides, audios, videos, etc. From the above it is proposed to develop learning tools capable of interacting with users autonomously. This leads to solving major learning problems using human computer and robotic human interaction. What is presented are two tools for learning the English language, the first based on augmented reality and the second using Nao humanoid robot.
Impacto de la narrativa de cuentos en el área de lenguaje: Subprueba de semejanzas de la escala Wechsler para preescolares
Authors: Acevedo-Martínez Norma Patricia , Ontiveros-Vargas Ángel Adrián , Herrera-Vargas Isela Vanessa , Santiesteban-Contreras María Tereza
Published: September 2020

Storytelling in preschool ages plays an important role in the development of expressive and comprehensive language. Objective: to determine the impact of storytelling in the subtest of similarities of the WWPSI-Spanish Wechsler Intelligence Scale in preschoolers. Methodology: mixed, non-experimental, observational, cross-sectional study, with descriptive statistical analysis and non-probabilistic sampling for convenience. The sample consisted of 21 preschool children between 5 and 6 years old. The total score of the evaluation is 22, in the first evaluation a maximum score of 15 and a minimum of 2 was obtained, an average of 8.80 and a standard deviation of 4.52. In the second evaluation, a maximum of 19 and a minimum of 7 were obtained, an average of 14.52 and a standard deviation of 4.42, demonstrating significant advances in skills for the semantic categories. Contribution: Stimulation through storytelling favors the development of the expressive and comprehensive language of children, so it is suggested that preschool programs include activities such as storytelling, as it is a fundamental tool for the improvement of cognitive skills and the integral development of children
Geomorphological conditions of formation of landslides hazards in the Western Caucasus and methods of their monitoring
Authors: Voskresenskaya Elena , Voskresensky Ivan , Sokratov Sergey , Suchilin Alexander , Shnyparkov Alexander , Ushakova Ludmila
Published: September 2020

Toppling, falling and sliding of slopes are widespread in the mountains of the Western Caucasus. The slope hazards on Aibga Ridge and in the Mzymta river basin determine the ecological and geomorphological conditions for construction and operation of first of all, the linear infrastructures (roads and railways). Investigation considered the characteristic of the recent gravity-induced processes and corresponding slopes, including topples, falls, slides and spreads. According to the research results, ecological-geomorphological zoning (allocation of ecological-geomorphological sub-zones) was carried out. The base for the sub-zones regionalization were the morphometric characteristics: the relative excess (m) between the conjugate landforms and slope angle. The possibilities of applying modern techniques for monitoring and preventing of dangerous slope processes were investigated. The monitoring technique for high-precision fixation of “movements” of dangerous slopes was considered, which included several stages of applying modern hardware tools (ground-based and aerospace remote sensing):

preliminary allocation of sections along a linear object that represent a potential hazard;
ground-based sensing, in which various geodetic instruments (laser robotic total station, laser scanner, digital stereo-camera, etc.) are positioned on a reference marks of geodetic control network to monitor object of interest;
analysis of satellite imagery data from various satellites (Landsat, Pléiades, ALOS, Sentinel) and transforming them into the adopted coordinate system of the research site;
use of unmanned aerial vehicles (UAVs) for local large-scale remote sensing, which allows to obtain large-scale ortho-photo-maps and digital elevation model of the surface of an investigated area.
Remote sensing and GPR study of the Raddle glacier of the Ridge Munku-Sardyk (the East Sayan)
Authors: Kitov Aleksandr , Denisenko Ivan , Lunina Oxana , Gladkov Andrey , Plyusnin Viktor , Ivanov Egor
Published: September 2020

The Munku-Sardyk (Eastern Sayan) glacier has been described and studied for more than 100 years. The first largest glacier of Peretolchina was studied in the most detailed detail. Radde's second-largest glacier is much weaker. Monitoring of surface characteristics of the Radde glacier by ground methods and using data of remote sensing of the Earth (RSE) has been carried out since 2006. In 2018, georadar profiling of this glacier was performed for the first time. As a result, it was possible not only to clarify its surface characteristics, but also to assess the power of the ice and the internal structure (a layer of firn, ice, bed). According to the RSE, its geometric changes have been revealed. Over 120 years, the open part of the Radde Glacier has shrunk from 0.4 to 0.09 km2, and the length from 1 to 0.4 km. It also revealed the division of the glacier into two parts and the intensive reservation of the bottom of the main part of the tongue by surface moraines and the formation of a glacial lake on the glacier itself in the lower part of the second half. Radar research using the Oko-2 georadar, allowed to determine the volume of ice of this glacier 0.003 km3 and the greatest thickness of the main ice body 42 m. The main glacier flows down from the Eskadriliy top, 3168 m, to the north, flows on the cross-bar and from it turns to the northeast, and at the bottom of the kar will continue to flow north again.
Egypt’s Reservations to the United Nations Convention on the Elimination of Discrimination Against Women and Women’s Rights in Egypt
Authors: Kazimov Necva B.
Published: September 2020

This paper addresses the role that the Convention on the Elimination of Discrimination Against Women (CEDAW) can play to improve women’s conditions and secure their rights in Egypt, in light of that country’s religious-based reservations to the UN convention and its recent constitutional amendment making the Shari`ah its principle source of legislation. Specifically, it addresses Egypt’s reservations to Article 16, which concerns the eradication of discrimination against women in cases of divorce, as this area has been the focus of recent legislative reform. The paper is limited to Egypt, because it is the leading Muslim state in providing women’s rights in the area of family law.
To the question of ukrainian scientists searching for potential partners in technology transfer
Authors: Melnyk-Melnykov P. H. , Piatchanina T. V. , Ohorodnyk A. N. , Herasymchuk S. M.
Published: September 2020

The article highlights modern approaches to finding potential partners in technology transfer by Ukrainian scientists. In developed countries, there are effective practical approaches that are not yet often used in the modern realities of Ukraine. Therefore, the purpose of the article is to study world practice and adapt it to local conditions. The article reviews foreign and domestic scientific publications on the practice of finding partners in technology transfer. The analysis of the best world methods allowed to develop recommendations for Ukrainian innovators. The structure of one-page technological profiles in the advertising description of the developed technology or product is analyzed in detail. It is revealed that the structure of technological profiles of the National Academy of Sciences of Ukraine as a whole corresponds to the world standards. Two other important elements in finding a licensee, investor or strategic partner are also considered, namely the “Elevator pitch” and the structure of the 7-minute presentation. The importance of emphasizing the unique advantages of the developed technology using the matrix of comparison of the main characteristics with competitors is noted. It was found that the development and placement of a technological profile is a necessary condition for promoting the developed innovation, but almost always not a sufficient condition for success in finding a potential partner. The analysis performed in the work shows that the simple placement of advertising descriptions of technologies in catalogs and specialized databases is often not enough when looking for potential partners. Proactive approach and persistent search for licensees and investors, using the methods of direct marketing described in the article is recommended.
Mathematical Models for the Prediction of Coagulation Activity in Patients with Paroxysmal Atrial Fibrillation
Authors:   B.Sc: Technical University of Sofia, Faculty of applied mathematics and informatics, Sofia, Bulgaria, Prodanova Krasimira , Negreva* Mariya ,   Department of Cardiology, Medical University of Varna, First clinic of cardiology, Varna University Hospital “St. Marina”, Varna, Bulgaria
Published: September 2020

Our previous studies showed activation of coagulation in the early hours of the clinical manifestation of paroxysmal atrial fibrillation (PAF). Plasma coagulation activity of factor II, factor V, factor VII, factor VIII, factor IX, factor X, factor XI, factor XII, vWF, tissue factor levels, FVIII, vWF, prothrombin fragment 1+2(F1 + 2) and fibrinopeptide A (FPA) were significantly increased as early as the first twenty-four hours of the disease. The results suggest that there is a correlation between the studied parameters and development of the disease. Aim: To search for a statistical model that predicts coagulation activity in PAF patients. Materials and methods: Coagulation parameters were examined in 51 PAF patients (26 males, 25 females; mean age 59.84 ±1.60 years, onset of PAF episode < 24h prior to hospitalization). Controls included 52 individuals (26 males, 26 females; mean age 59.50 ± 1.46 years) with no prior anamnestic or ECG AF data, corresponding to patients in sex, age, BMI and comorbidities. A linear regression model was used to predict coagulation activity in PAF. Regression models showed good correlation between the duration of arrhythmia and six of the fourteen coagulation parameters studied: F1+2 (r = 0.83, p <0.001), FPA (r = 0.84, p <0.001), FVIII levels (r = 0.85, p <0.001) as well as activity of FII (r = 0.83, p <0.001), FVIII (r = 0.83, p <0.001) and FXII (r = 0.78, p <0.001). Changes in F1+2 plasma levels were most sensitive to PAF duration, where the contribution of duration to the values of the indicator is the greatest (b = 15.31). Conclusion: Linear regression analysis allowed us to create models with a high correlation coefficient for predicting the values of F1+2, FPA, FVIII levels, as well as activity of FII, FVIII and FXII in PAF patients. These models could allow for quantification of the procoagulatory process and thrombotic potential of the disease.
Protective effect of Nannochloropsis Oculata against mercuric-induced histopathological alterations in the kidney of Nile tilapia
Authors: Mamdouh Alzahraa , Zahran Eman , Mohamed Fatma , Zaki Viola
Published: September 2020

Objective: The present study was designed to evaluate the toxic effect of sublethal concentration of mercuric chloride (0.3 mg/L HgCl2) on histopathological lesions in the kidney of Nile tilapia (O. niloticus) and the protective effect of microalgae, Nannochloropsis oculata (N. oculata) against the induced tissue alterations for 3 weeks. Design: Randomized controlled study Animals: Nile tilapia Procedures: Fish were randomly assigned to 4 groups, group1: control (basal diet), group 2 (Hg/ exposed to HgCl2 at a dose of 0.3 mg/L (1/4 of LC50), and fed basal diet), group 3: (Hg+N5, similar to group2, but fed diet supplemented with N. oculata 5% and group 4 (Hg+N10, similar to group2, but fed diet supplemented with N. oculata 10 %. Two fish from each aquarium tank (6 fish/group) were sampled at weeks 1, 2, and 3 of the experiment. The posterior kidney was dried out in a graded ethanol series and then embedded in paraffin. Each block of tissue was cut into serial sections (5 μm thick) and stained with hematoxylin and eosin (H&E). Results: Histopathological alterations were induced following mercuric exposure in a time-dependent manner. The kidney showed congestion, hemosiderosis, and hemorrhage with vacuolated tubular epithelium, hyaline droplet degeneration, and necrosis of the tubular epithelium. Supplementation with N. oculata, particularly at 10 %, succeeded in alleviating the histopathological induced lesions in the kidney. Conclusion and clinical relevance: Our findings demonstrate that HgCl2 has nephrotoxic properties that led to severe histopathological alterations in the kidney of Nile tilapia, while dietary supplementation with N. oculata was able to alleviate the induced kidney alterations.
DeepVir - Graphical Deep Matrix Factorization for In Silico Antiviral Repositioning: Application to COVID-19
Authors: Majumdar Angshul , Mongia Aanchal , Chouzenoux Emilie , Jain Stuti
Published: September 2020

This work formulates antiviral repositioning as a matrix completion problem where the antiviral drugs are along the rows and the viruses along the columns. The input matrix is partially filled, with ones in positions where the antiviral has been known to be effective against a virus. The curated metadata for antivirals (chemical structure and pathways) and viruses (genomic structure and symptoms) is encoded into our matrix completion framework as graph Laplacian regularization. We then frame the resulting multiple graph regularized matrix completion problem as deep matrix factorization. This is solved by using a novel optimization method called HyPALM (Hybrid Proximal Alternating Linearized Minimization). Results on our curated RNA drug virus association (DVA) dataset shows that the proposed approach excels over state-of-the-art graph regularized matrix completion techniques. When applied to in silico prediction of antivirals for COVID-19, our approach returns antivirals that are either used for treating patients or are under for trials for the same.
INVESTOR SENTIMENT AROUND BUYBACK IN INDIAN STOCK MARKET
Authors: Varsha P  , Nithin Jose
Published: September 2020

While Buyback helps companies to invest in themselves by reducing the number of outstanding shares in the market, it increases the investor sentiment with respect to the company as the investors expect an increased Earnings Per Share, When the Earnings Per Share increases, the market react positively and shares prices will increase. This study attempts to examine the significance of stock price behavior around the public announcement of buyback. The effect of public announcement is studied by analyzing the behavior of abnormal returns of ten companies, which made buyback announcement during the financial year 2018–19. The companies were selected from securities exchange board of India (SEBI) and National Securities Exchange (NSE) website that portrays the public announcement of all such companies. This is an event study which attempts to measure the valuation effect of a corporate event, namely public announcement of buyback by examining the response of the stock price around the announcement of the event. To test the impact of public announcement Abnormal Returns (AR) and Cumulative Abnormal Returns (CAR) are computed. The study concludes that the buyback announcement does not have any significant impact on the share price.
KEYWORDS: Buyback, CAR, Abnormal Returns, Investor sentiment
PENGARUH PEMBERIAN EKSTRAK ETIL ASETAT BUAH DEWANDARU (Eugenia uniflora L.) TERHADAP GAMBARAN HISTOPATOLOGI HATI MENCIT YANG DIINDUKSI KARBON TETRAKLORIDA (CCl4)
Authors: Santoso Puguh , Yuda Putu Era Sandhi Kusuma
Published: September 2020

Tanaman dewandaru (Eugenia Uniflora L.) telah dimanfaatkan oleh masyarakat sebagai obat tradisional. Karbon tetraklorida (CCl4) merupakan zat kimia yang bersifat toksik terhadap hepar. Metabolisme CCl4 menghasilkan radikal bebas CCl3- yang dapat mengakibatkan kerusakan pada sel hati. Penelitian ini bertujuan untuk mengetahui efek ekstrak etil asetat buah dewandaru pada histopatologi hati mencit yang diinduksi dengan karbon tetraklorida. Penelitian ini merupakan penelitian eksperimental dengan randomized control group post test only design, menggunakan sampel 15 ekor mencit yang dibagi menjadi tiga kelompok. Kelompok kontrol negatif diberi CCl4 1,3 % selama 7 hari pada hari ke 4, kemudian diberi CCl4 1,3% dan ekstrak etil asetat buah dewandaru dengan dosis 0,5 mg/g BB sebanyak 1 ml secara bersamaan selama 7 hari, diberi CCl4 1,3% dan ekstrak etil asetat buah dewandaru dengan dosis 1 mg/g BB sebanyak 1 ml secara bersamaan selama 7 hari. Pada hari ke-11 mencit dikorbankan dan dibedah untuk diambil hatinya, pembuatan preparat histopatologi, dan pemeriksaan histopatologi hati mencit. Data hasil pemeriksaan dianalisis secara deskriptif kualitatif. Dari hasil penelitian dapat disimpulkan bahwa gambaran histopatologi hati mencit yang diinduksi karbontetraklorida dan diberikan ekstrak etil asetat buah dewandaru dapat mengurangi degenerasi melemak dengan memperkecil vakuola-vakuola lemak didalam sitoplasma sel hati. Namun, nekrosis pada kelompok kontrol dan kelompok perlakuan ekstrak etil asetat buah dewandaru sudah sebagian menunjukkan adanya perubahan pada sel hati mencit.
UJI EFEKTIVITAS AFRODISIAKA DARI EKSTRAK ETANOL BUNGA KEMBANG SEPATU (Hibiscus rosa-sinensis L.) PADA TIKUS (Rattus norvegicus L.) PUTIH JANTAN
Authors: Adrianta Ketut Agus , Wardani I Gusti Agung Ayu Kusuma
Published: September 2020

Afrodisiaka adalah semua bahan baik obat dan makanan yang dapat membangkitkan gairah seksual. Di Indonesia terdapat begitu banyak bahan tanaman obat herbal alami yang dapat digunakan sebagai afrodisiaka. Salah satu tanaman yang dipercaya mempunyai khasiat sebagai afrodisiaka adalah tanaman kembang sepatu (Hibiscus rosa-sinensis L). Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol bunga kembang sepatu (Hibiscus rosa-sinensis L.) sebagai afrodisiaka pada tikus (Rattus norvegicus L.) putih jantan. Ekstrak bunga kembang sepatu diberikan secara oral setiap hari selama 8 hari. Terdapat 3 kelompok perlakuan yaitu kelompok kontrol yang diberikan akuades, kelompok perlakuan I diberikan ekstrak bunga kembang sepatu dengan dosis 1 g/KgBB, dan kelompok perlakuan II diberikan ekstrak bunga kembang sepatu konsentrasi 2g/KgBB, Parameter pengukuran berupa introduction (pendekatan), climbing (menunggang), dan coitus (kawin). Hasil penelitian menunjukkan bahwa ekstrak bunga kembang sepatu dapat meningkatkan libido tikus putih jantan. Dapat disimpulkan bahwa pemberian ekstrak bunga kembang sepatu secara oral selama 8 hari efektif meningkatkan libido tikus jantan pada dosis 1g/KgBB.
EFEKTIVITAS AFRODISIAKA DARI EKSTRAK ETANOL JAHE MERAH (Zingiber officinale ROSCOE) PADA TIKUS (Rattus norvegicus L.) PUTIH JANTAN
Authors: Wardani I Gusti Agung Ayu Kusuma , Santoso Puguh
Published: September 2020

Gangguan reproduksi kini banyak dialami terutama pada pria akibat berbagai faktor, jahe merah sering digunakan untuk mengatasi gangguan seksual pada pria. Jahe merah dilaporkan memiliki efek sebagai afrodisiaka. Afrodisiaka adalah semacam zat perangsang yang konon dapat meningkatkan gairah seks. Penelitian ini bertujuan untuk mengetahui efek pemberian ekstrak etanol jahe merah (Zingiber officinale Roscoe) sebagai afrodisiaka pada tikus (Rattus novergicus L.) putih jantan. Jahe merah diekstraksi dengan cara maserasi dengan etanol 80%. Dibuat menjadi ekstrak kental melalui proses evaporasi. Ekstrak kental jahe merah diencerkan dengan konsentrasi 25% dan 50%. Tikus dibagi menjadi 3 kelompok perlakuan yaitu kelompok kontrol yang diberikan aquadest, kelompok perlakuan diberikan ekstrak jahe merah dengan konsentrasi 25% dan 50%. Ekstrak jahe merah diberikan secara oral selama 7 hari. Parameter yang diamati adalah frekuensi pendekatan (introduction), menunggangi (climbing), dan kawin (coitus). Hasil penelitian menunjukkan ekstrak jahe merah dapat meningkatkan libido pada tikus jantan. Dengan perbedaan bermakna antara kelompok kontrol dengan kelompok konsentrasi 25% dan 50%. Dapat disimpulkan bahwa pemberian ekstrak jahe merah efektif meningkatkan libido tikus jantan selama 7 hari penelitian pada konsentrasi 25%.
SKRINING FITOKIMIA DAN ANALISIS KROMATOGRAFI LAPIS TIPIS EKSTRAK TANAMAN PATIKAN KEBO (Euphorbia hirta L.)
Authors: Yuda Putu Era Sandhi Kusuma , Cahyaningsih Erna , Winariyanthi Ni Putu Yuni
Published: September 2020

Tanaman obat mengandung berbagai macam kandungan fitokimia yang berperan dalam pengembangan obat. Herba Patikan Kebo (Euphorbia hirta L.) adalah salah satu tanaman obat yang tergolong dalam Famili Euphorbiaceae. Penggunaan E.hirta sebagai obat tradisional telah dilaporkan di beberapa daerah termasuk di Bali. Secara tradisional tanaman ini diketahui dapat digunakan untuk mengobati berbagai macam penyakit, seperti radang tenggorokan, disentri, diare, asma dan bronchitis sehingga berpotensi sebagai alternatif bahan baku obat tradisional. Untuk dapat dikembangkan sebagai bahan obat tradisional, perlu diketahui kandungan senyawa metabolit sekunder yang terdapat pada herba Patikan Kebo baik secara kualitatif maupun kuantitatif sebagai salah satu parameter standarisasi. Namun, saat ini data mengenai karakteristik metabolit sekunder herba Patikan Kebo yang tumbuh di Bali masih terbatas. Penelitian ini bertujuan untuk mengetahui senyawa metabolit sekunder yang terkandung pada herba Patikan Kebo melalui skrining fitokimia dan analisis Kromatografi Lapis Tipis (KLT). Ekstraksi dilakukan menggunakan pelarut etanol 75% dengan cara maserasi, dan diperoleh rendemen ekstrak sebanyak 6,87%. Pengujian kandungan metabolit sekunder pada ekstrak herba patikan kebo dilakukan secara skrining fitokimia. Selanjutnya uji KLT dilakukan untuk mempertegas keberadaan golongan senyawa yang positif pada skrining fitokimia, dan mengetahui profil kromatografi dari ekstrak tersebut. Setelah diuji secara skrining fitokimia dan analisis KLT, diperoleh hasil herba Patikan Kebo yang digunakan dalam penelitian ini mengandung beberapa senyawa metabolit sekunder diantaranya flavonoid, tanin, steroid dan antrakuinon. Sistem KLT yang digunakan dalam penelitian ini dapat memisahkan kandungan fitokimia tersebut dan memberikan hasil positif yang mempertegas hasil skrining fitokimia.
PERBANDINGAN PENGGUNAAN ANTIBIOTIK TUNGGAL DAN KOMBINASI PADA PASIEN PEDIATRIK DENGAN GASTROENTERITIS AKUT (GEA) DI RSUD WANGAYA DENPASAR
Authors: Meriyani Herleeyana , Udayani Ni Nyoman Wahyu
Published: September 2020

Tujuan dari penelitian ini adalah untuk mengetahui perbandingan efektivitas penggunaan antibiotik tunggal dan kombinasi pada pasien pediatrik dengan gastroenteritis akut (GEA) di Instalasi Rawat Inap RSUD Wangaya Denpasar. Penelitian ini menggunakan metode cross-sectional dengan pengumpulan data bersifat retrospektif terhadap rekam medis pasien pediatrik dengan GEA yang menggunakan antibiotik selama Bulan Januari 2016 sampai Bulan Maret 2017. Teknik pengambilan sampel menggunakan non-probability sampling (purposive sampling). Data dianalisis statistik dengan taraf kepercayaan 95%. Efektivitas terapi GEA dalam penelitian ini dilihat dari parameter LOS (Length of Stay) dan lama hilangnya gejala (duration of symptoms). Berdasarkan hasil penelitian populasi sebanyak 679 pasien dan jumlah sampel yang telah memenuhi kriteria inklusi sebanyak 90 pasien yang terdiri atas 62 % laki laki dan 38% perempuan. Sebanyak 82 % dari subjek penelitian adalah balita, 11 % anak anak dan 7% remaja. Sebanyak 76% dari subjek penelitian menggunakan penggunaan antibiotik tunggal dan 33% menggunakan antibiotik kombinasi. Berdasarkan Uji Mann-Whitney tidak terdapat perbedaan bermakna antara efektivitas penggunaan antibiotik tunggal dan kombinasi terhadap LOS (p = 0,579) dan lama hilangnya gejala diare (p = 0,726). Sehingga baik penggunaan antibiotik tunggal dan kombinasi tidak berpengaruh terhadap LOS dan lama hilangnya gejala diare.
PENERIMAAN PASAR TERHADAP BODY BUTTER MASERAT BERAS MERAH (Oryza glaberrima Steud.)
Authors: Suena Ni Made Dharma Shantini , Syirvia Alfiana Naili , Antari Ni Putu Udayana
Published: September 2020

Beras berwarna mengandung lebih banyak antosianin dan antioksidan daripada beras tanpa warna (Sutharut, 2012). Beras merah sebagai salah satu jenis beras berwarna berpotensi dikembangkan menjadi produk yang mampu memberikan nilai tambah bagi produsen beras merah, maupun masyarakat pengguna produk tersebut. Untuk itu telah dilakukan formulasi body butter dari maserat beras merah. Untuk mengetahui potensi pasar produk yang dihasilkan, diperlukan penelitian untuk mengetahui penerimaan pasar terhadap body butter beras merah. Penelitian dilaksanakan dengan metode analisis deskriptif menggunakan kuesioner. Responden adalah masyarakat di Kota Denpasar yang memenuhi kriteria inklusi penelitian. Responden diminta untuk menilai kualitas body butter yang meliputi warna, aroma, kekentalan, kemudahan saat digunakan, kenyamanan saat digunakan, kemampuan melembabkan kulit, dan kemampuan meresap ke dalam kulit. Setelah dilakukan analisis data secara deskriptif diperoleh bahwa persentase penerimaan body butter maserat beras merah adalah 82.31% sehingga termasuk dalam kategori sangat diterima di pasaran.