bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Adenotonsillectomy on Obesity Risk: A Case-Control Study in Paediatric Population
Authors: Morreale Chiara , Musolino Gianluca , Rosa Sara La , Bresesti Ilia , De Bernardi Francesca , Agosti Massimo
Published: March 2024

Childhood obesity is one of the most important problem in our society with a multifactorial aetiology. Adenoidectomy and tonsillectomy are one of the most frequent paediatric surgeries. Primary aim of our retrospective study is to evaluate the possible relationship between tonsillectomy and/or adenoidectomy and the subsequent development of childhood obesity.
METHODS: 267 children (3-17 years) were enrolled and n=9 are excluded because of their elevated BMI before surgery or their therapy. Case group: 158 children (98 male (M), 60 female (F)) with essential obesity (≥97°P) and no evidence of obesity complications at the first endocrinology visit (T0). Control group=100 non obese children (37 M, 63 F) with subclinical hypothyroidism. We collect anthropometric parameters (height, weight, BMI) at T0, pre and post-surgery.
RESULTS: ENT surgery was more frequent in case group than control one (n=46 vs n=7, p-value <0,0001). The mean period between the date of surgery and the onset of obesity was 3,5 years (6 months-10 years). The Odds ratio (OR) between risk to develop obesity after ENT surgery is five times higher in the case group than the control one, (OR 5.5 p-value <0,0001).
CONCLUSION: The surgical exposure seems to be a risk factor for obesity development. Actually, the weight gain might be related to improvement of lifestyle and olfactory-taste perception.
Level of Evidence: Level III, case-control analytic trial
ID1 protein inhibitor depresses low-oscillating shear stress-mediated EndMT and atherosclerosis by Snail and Wnt/β-catenin signalling pathways
Authors: Jun Qiu , Yang Xi , Wang Bingyu , Sun Xinyi , Li Youhong , Lian Jiangfang , Zhou Jianqing
Published: March 2024

The lateral pressure exerted by blood on the vessel wall, called low oscillating shear stress(OSS), destroys the endothelial cell barrier function through a process called EndMT and promotes the occurrence of atherosclerosis. The specific mechanism by which OSS regulates EndMT is still unclear. Inhibitor of differentiation 1 (ID1) is controlled by shear stress as an essential force-sensitive factor, and little is known about the effect of ID1 on EndMT in OSS-mediated atherosclerosis. This study investigated the impact of ID1 inhibitors on OSS-mediated EndMT in ApoE−/− mice and TGF-β1-induced human aortic endothelial cells (HAECs). First, we found that the expression of ID1 was down-regulated. At the same time, EndMT and plaque formation occurred in the ligated left common carotid artery (OSS) compared with the unligated right common carotid artery. Then, our results showed that the ID1 inhibitor AGX51 attenuated EndMT in atherosclerosis plaques in OSS mice. However, in vitro studies show that ID1 is upregulated in TGF-β1-treated HAECs and induces EndMT.sh-ID1 or AGX51 to inhibit the EndMT process and restore the migratory ability of endothelial cells. Furthermore, ID1 overexpression promoted the occurrence of EndMT.In addition, inhibition of ID1 may inhibit OSS-induced EndMT by regulating EndMT-specific transcription factors Snail and Wnt/β-catenin signalling pathway in vivo and in vitro by Immunohistochemistry and Western blot. These results suggest that ID1 inhibitors regulate the occurrence and development of low oscillating shear stress-mediated EndMT and atherosclerosis by Ctrlling Snail and Wnt/β-catenin signalling pathways.
Synthetic high b-value FOCUS-MUSE diffusion-weighted imaging in identifying early-stage cervical cancer
Authors: Mei Wancui , Tang Qian , Sang Ling , Chen Wen , Li Chengcheng , Wang Sai , Zhou Qiqi , Liu Weiyin , Xu Lin
Published: March 2024

Background
Early diagnosis of cervical cancer based on FIGO stage is essential for treatment strategies, we aimed to explore the classifying ability of synthetic high-b-value FOCUS-MUSE DWI in cervical cancer FIGO stage including image quality and diagnostic efficiency.
Methods
55 patients with cervical cancer and 33 volunteers were prospectively recruited. All patients and volunteers underwent three DWI sequences (FOCUS-MUSE DWI with a 13b protocol: b = 0, 25, 50, 75, 100, 150, 200, 400, 600, 800, 1000, 1200, 1500s/mm2 and 5b protocol: b = 0, 100, 400, 800, 1500s/mm2, the FOCUS DWI with the same 5b protocol. Two experienced radiologists conducted subjective and objective evaluation on 5 sets of images (sFOCUS-MUSE DWIb=800, sFOCUS-MUSE DWIb=1500, syFOCUS-MUSE DWI13b,1500, syFOCUS-MUSE DWI5b,1500, syFOCUS DWI5b,1500) and also measured ADC values. Paired T-test or Wilcoxon signed rank test were used to compare image quality and ADC values, and ROC curve was used to analyze diagnostic efficiency.
Results
The high-b-value syFOCUS-MUSE DWI5b/13b,1500 had higher subjective and objective image quality than sFOCUS-MUSE DWIb=1500 (P < 0.05). Compared with syFOCUS DWI5b,1500 and sFOCUS-MUSE DWIb=800, syFOCUS-MUSE DWI5b,1500 had better overall image quality and lesion conspicuity (P < 0.05). syFOCUS-MUSE DWI5b,1500 derived syADCmean, syADCmaximum and syADCminimum had equivalent AUCs to those using sFOCUS-MUSEb=800 and sFOCUS-MUSEb=1500, but superior to those using syFOCUS5b,1500.
Conclusions
On 3.0T MR scanner, syFOCUS-MUSE DWI provided higher overall image quality and lesion clarity than sFOCUS-MUSE DWI and syFOCUS DWI. 5b-protocol synthetic high-b-value FOCUS–MUSE DWI greatly shortened the scan time and histogram-derived syADC values (syADCmean, syADCmaximum, syADCminimum) offered more reliable diagnostic performance on cervical cancer with different FIGO stage than those of sFOCUS-MUSE and syFOCUS.
Solving Multi-Agent Games on Networks
Authors: Vaknin Yair , Meisels Amnon
Published: March 2024

Multi-agent games on networks (GoNs) have nodes that represent agents and edges that represent interactions among agents. Binary GoNs are composed of 2-Players games on each of their edges. Non binary GoNs have games that are played by all agents in each neighborhood.Solutions to games on networks are stable states (i.e., pure Nash equilibria), and in general one is interested in efficient solutions (i.e., of high social welfare).Incentives, in the form of side payments among agents, are known to promote increased-efficiency stable states.
This study addresses the multi-agent aspect of games on networks - a system of multiple agents that compose a game and seek a solution. The agents playing the game are assumed to be strategic and the present study proposes an iterative distributed algorithm that lets the agents interact (i.e., negotiate) in neighborhoods in a process that guarantees the convergence of any multi-agent game on network to a stable state.The proposed algorithm treats the game as a repeated social choice action that takes place in one neighborhood at a time. A truthful enforcing mechanism is integrated into the process, collecting agents' valuations and computing incentives on the fly while eliminating strategic behavior. This method - the TECon algorithm - is proven to converge to solutions that are at least as efficient as the initial state, for any game on network.A specific version of the algorithm is given for the class of public goods games, where the main properties of the algorithm are guaranteed even when the strategic agents playing the game consider their possible future valuations when interacting.This opens an interesting new research direction on application-specific derivatives of TECon that, similarly to the case of public goods games, may lead to solutions of greater efficiency. An extensive experimental evaluation on randomly generated games on networks demonstrates that the TECon algorithm outperforms former solving methods on several classes of games on networks.
A Glutamine metabolism-related genes prognosis biomarker for predicting prognosis in colorectal carcinoma
Authors: Ma Na , Zhang Siming , Yu Sihan , Shen Rong , Zhang Chencheng , Diao Xun , Wang Qinghui , Wu Zhijun , Liu Jibin
Published: March 2024

Background
Colorectal cancer (CRC) is one of the most common types of tumor in the gastrointestinal tract worldwide. Amino acid metabolism is closely associated with malignant tumor development, infiltration, metastasis and recurrence. More studies are needed to understand the relationship between glutamine metabolic profile and prognosis of colorectal cancer.
Methods
In our study, we obtained transcriptomic and related clinical information data of CRC patients from The Cancer Genome Atlas (TCGA) database. Consensus clustering analysis was used to classify CRC patients into various molecular subtypes and identify differential expression of genes related to immunity and glutamine metabolism. We applied univariate and multivariate COX regression and lasso regression analyses to construct a risk assessment model incorporating four genes related to glutamine metabolism, and the CRC samples were categorized into high- risk and low-risk groups, and the correlation between the risk model scores and TME, immune cell infiltration, and cellular mutations was investigated. Finally, we validated the correlation of ADIPOQ using immunohistochemistry in colorectal cancer tumor tissues. In addition, this study was externally validated using the GSE39582 dataset from the GEO database.
Results
By consistent cluster analysis, we identified two different molecular subtypes. It was also found that different GMRG subtypes were associated with patients' clinicopathologic features, prognosis and TME cell infiltration characteristics. Meanwhile, a predictive model on the basis of the GMRGS risk score was developed and the validity of the predictive ability of the model was verified in internal and external datasets. Furthermore, in terms of immune infiltration and cellular mutations, we observed significant variability between high and low risk groups.
Conclusion
Our study identified four glutamine metabolism-related genes affecting TME, clinicopathological features, immune landscape, and prognosis-related prediction of CRC, and these findings in our study will better understand the mechanisms by which reprogramming of glutamine metabolism is associated with the developmental progression of CRC and will facilitate to improve the treatment of tumors.
Extracardiac Manifestations Fail to Predict the Severity of Cardiac Phenotype in Children and Young Adults with Marfan Syndrome
Authors: John Sheba , Young Luciana T. , Lacro Ronald V. , Hoskoppal Arvind , Ou Zhining , Presson Angela , Johnson Joyce T. , Andrade Lauren , Minich L. LuAnn , Menon Shaji
Published: March 2024

We performed a secondary analysis of the Pediatric Heart Network Marfan Trial public-use database to evaluate associations between extracardiac features and cardiac and aortic phenotypes in study participants. Aortic aneurysm phenotype was defined as aortic root Z-score ≥ 4.5, aortic root growth rate ≥ 75th percentile, aortic dissection, and aortic surgery. Severe cardiac phenotype was defined as aortic dissection, aortic Z-score ≥4.5, aortic valve surgery, at least moderate mitral regurgitation, mitral valve surgery, left ventricular dysfunction, or death. Extracardiac manifestations were characterized by specific organ system involvement and by a novel aggregate extracardiac score that was created for this study based on the original Ghent nosology. Logistic regression analysis compared aggregate extracardiac score and systems involvement to outcomes. Of 608 participants (60% male), the median age at enrollment was 10.8 years (interquartile range: 6, 15.4). Aortic aneurysm phenotype was observed in 71% of participants and 64% had severe cardiac phenotype. On univariate analysis, skeletal (OR: 1.95, 95% CI: 1.01, 3.72; p = 0.05), skin manifestation (OR: 1.62, 95% CI: 1.13, 2.34; p = 0.01) and aggregate extracardiac score (OR: 1.17, 95% CI: 1.02, 1.34; p = 0.02) were associated with aortic aneurysm phenotype but were not significant in multivariate analysis. There was no association between extracardiac manifestations and severe cardiac phenotype. Thus, the severity of cardiac manifestations in Marfan syndrome was independent of extracardiac phenotype and aggregate extracardiac score. Severity of extracardiac involvement did not appear to be a useful clinical marker for cardiovascular risk-stratification in this cohort of children and young adults with Marfan syndrome.
Short-term outcomes of 47 selective laparoscopic lymph node dissection for rectal cancer: A Retrospective Study
Authors: xue xiajuan , Guo Yincong , Lin Shuijie , Zeng Qunzhang
Published: March 2024

Purpose: The aim of this study is to analyze the safety, feasibility and short-term oncology outcomes of selective laparoscope lateral lymph node dissection(LLND) with total mesorectal excision(TME) surgery.
Methods: Between December 2019 and May 2023, LLND with TME surgery was performed in 47 selected patients with advanced rectal cancer. Surgical complications and 2-year oncology survival outcomes were analyzed in the study.
Results: All 47 procedures were technically successful without the need for conversion to open surgery. The mean operation time was 200.6 minutes (range, 135-321 minutes) and mean estimated blood loss was 92.9 ml (range, 10-2000 ml). The most common postoperative complications were anastomotic(8.5%,n=4), ileus (6.4%, n=3), chyle leakageleakage (4.3%, n=2). Lateral pelvic lymph node metastases(LPNM) was found in 19 (40.4%) patients. When divided into LNP positive or negative groups, there were no significant impact on the OS (94.4%vs100%, Log rank p=0.596) and LFRS(76.7%vs89.6%, Log rank p=0.210) , except DFS (58.3%vs90.2%,Log rank p=0.005). Subgroup analysis showed that there was similar short-tem survival outcomes between pN+ group and internal iliac metastasis group(Log rank p of OS,LFRS,DFS were all＞0.05). LRFS and DFS in obturator or external iliac metastasis group were worse than those in internal iliac metastasis group when the follow-up time was extended(Log rank p of LFRS, DFS were 0.05, 0.063 , respectively).
Conclusion: Selective laparoscopy LLND for rectal cancer are safety and feasibility, and its complications are manageable. Oncology survival outcomes for LPNM limited to the internal iliac are similar to pN+ stage , therefor it should be treated positively.
Anatomical, chemical, physical and mechanical properties of E. urophylla× grandis and E. globulus at different ages and heights in Yunnan of China
Authors: Li Chunping , Tian Kun , Su Xinlong , Li Yuan , Du Guanben , Zhan Hui , Wang Changming , Wan Hui
Published: March 2024

In order to make full use of Eucalyptus resources in Yunnan and to realize the oriented cultivation of Eucalyptus plantations and high-value utilization of Eucalyptus for wood composites, this paper analyzed the change pattern of basic wood properties and characteristics including the wood anatomical features, chemical components, physical and mechanical properties, as well as X-ray diffraction of 6–9 years old E. urophylla×grandis 3229 and E. globulus. The results showed that the cellulose content, crystallinity and hot water extractives of Eucalyptus decreased with wood age, while the lignin and hemicellulose content showed the opposite trend; pH value was positively correlated with wood height and negatively correlated with wood age. The basic density of E. urophylla×grandis and E. globules was 0.46 ~ 0.54 g/cm3, belonging to medium-low density wood. The dimensional stability and bengding strength of E. globulus were higher than those of E. urophylla×grandis; the compressive strength of E. urophylla×grandis was grade 5 (95.45 ~ 113.54 MPa) and its hardness was grade 2–3(The end hardness of 9 year reaches 5357.97 MPa.). The study showed that E. urophylla×grandis over 7 to 8 years and E. globulus over 6 year had diameters and mechanical properties that meeting the requirement of Chinese industrial timber standards.
Two-stage robust reserve coordinated operation based on real-time price mechanism
Authors: Deng Huiqiong , Hui Wu , Liang Zhiwei , Tong Zhe , Shen Junfu
Published: March 2024

In order to cope with the impacts of uncertainty factors on the reliability and economy of system operation, a two-stage robust reserve optimization model is proposed to take into account the real-time price day-ahead and intraday. The proposed model consists of two phases: the first phase is the day-ahead decision-making phase, which improves the flexibility of grid operation by establishing a demand response model based on the load classification under real-time price; and the second phase is the intraday decision-making phase, which takes into account the uncertainty of the wind - photovoltaic power and the failure of the transmission line in order to improve the robustness of the grid in coping with the uncertainties. The day-ahead decision-making is a deterministic optimization problem, which is solved by a linear programming problem, while the intra-day decision-making is an adaptive robust optimization problem, which is solved by using the Strong Dyadic Theory (SDT) method. By combining the power data of wind and photovoltaic fluctuation intervals and load demand of a regional power grid, a simulation model is constructed to verify that the proposed robust model is effective in optimizing the reserve capacity of the system operation under multiple uncertainties, reducing the scheduling cost of the system in the worst scenario, and ensuring the safe and reliable operation of the system.
Efficasy of pancreaticojejunostomy of the pancreatic stump during distal or central pancreatectomy
Authors: Hirashita Teijiro , Fujinaga Atsuro , Nagasawa Yuiko , Orimoto Hiroki , Amano Shota , Kawamura Masahiro , Kawasaki Takahide , Kawano Yoko , Masuda Takashi , Endo Yuichi , Inomata Masafumi
Published: March 2024

Background: A stapler is usually used for transection and closure of the pancreas in distal pancreatectomy (DP) or central pancreatectomy (CP). When the pancreas is transected to the right of the portal vein, it is difficult to use a stapler and clinically relevant postoperative pancreatic fistula (CR-POPF) frequently occurs. We report on the efficacy of pancreaticojejunostomy (PJ) of the pancreatic stump for patients in whom stapler use is difficult.
Methods: Patients who underwent DP or CP were enrolled in this study. The pancreas was usually transected by a stapler, and ultrasonic coagulating shears (UCS) were used depending on the tumor situation. When using UCS, hand-sewn closure or PJ was performed for the pancreatic stump. The relationship between clinicopathological factors and the methods of pancreatic transection and closure were investigated.
Results: In total, 164 patients underwent DP or CP, and the pancreas was transected with a stapler in 150 patients and UCS in 14 patients. The rate of CR-POPF was higher and the postoperative hospital stay longer in the stapler group than in the UCS group. PJ of the pancreatic stump, which was performed for 7 patients, did not worsen intraoperative factors. CR-POPF was not seen in these 7 patients, which was significantly less than that with hand-sewn closure.
Conclusions: PJ of the pancreatic stump during DP or CP reduces CR-POPF compared with hand-sewn closure and may be useful especially when the pancreas is transected to the right of the portal vein.
Recursive K-index and iterative H-index
Authors: Knar Eldar
Published: March 2024

An aggregated recursive K-index (Kazakhstan Science Index) is proposed as the “Kazakhstan Science Citation Index” (Forum of Higher Education and Science-2023, 08/24/2023, Sayasat Nurbek, Ministry of Education and Science of the Republic of Kazakhstan).
In particular, it is proposed to switch from a pure strategy for assessing the quality and effectiveness of R&D using the H-index (Hirsch index) to a mixed strategy (in the context of publication activity as a combination of cooperative and noncooperative games) using the K-index on subnational and H-index on international or differentiated levels. In the context of a hybrid strategy of the scientist's payoff functions. This transition is correct and in demand for a number of national scientific systems with limited financial, material, infrastructural and linguistic (in terms of the English language) potential. Scientific systems with highly developed indigenous (autochthonous) characteristics are also needed insome scientific areas.
Some results on the counterproductivity of the Hirsch index for the Kazakh scientific system are presented. In particular, a significant increase in the H-index of Kazakh scientists was noted as the degree of scientific localization (national participation) decreased and as the degree of “foreign content” in science-intensive content increased within the framework of international joint collaboration. The abilityof the delocalization of local scientific content in joint publications to increase the H-index of Kazakh scientists was discovered. This effect is interpreted and confirmed by the positive and negative correlation coefficients between the Hirsch indices and the form and degree of participation (role functions) of Kazakh scientists in joint publications.
Comparative genomic studies of Tomtom and Nuaimi sheep breeds of Bahrain, and Asian and European sheep breeds revealed selection signatures
Authors: Tibbo Markos , Jawasreh Khaleel , Stella Alessandra , Al-Najar Muneer , Mahmoud Atia , Yusuf Ebrahim , Boettcher Paul , Looft Christian
Published: March 2024

The segments of the genome harboring genes subject to past selection because of their biological relevance can be identified due to their lower genetic divergence and distinctive regional linkage disequilibrium (LD) patterns. The origins of the sheep breeds known as Tomtom and Nuaimi in Bahrain are unknown, as are the special genetic variants that they carried throughout their evolution and presumably differ from ancient breeds native to Europe and Asian. We pinpointed signals of selection in sheep breeds by comparing the regional genomic (50k SNp chip) differences in LD variation between the Tomtom and Nuaimi sheep breeds with the Afshari, European Mouflon, Asian Mouflon, and Zel breeds. The autosomal genome's LD variation among breeds was compared using the VarLD approach. The NCBI assembly was used to assess the genomic regions bearing the top 0.01 and 0.1 percentiles of signals, determine the genes in those regions, and compare those regions with previously published selection signatures. The wild Mouflon (Asian and European) and Tomtom breeds were divided into three separate components by the PCA, whereas Nuaimi, Zel, and Afshari were grouped inside a single quartile and given special distinction because their individuals looked to be close to one another (genetically related). A total of 59 genes were found to be close to the selection signatures (94 selection signatures) detected on various ovine chromosomes, and many were crucial for reproductive and productive attributes that were influenced by selection as the Tomtom and Nuaimi sheep breeds evolved. According to the genome scan, the Tomtom sheep breed is genetically distant as it was isolated in a separate quartile, far from the Nuaimi, Zel, and Al-Afshari on the one hand, and Asian and European Mouflon on the other. The differences found between the studied breeds combinations may have resulted from special genomic selection signals (94) detected on different chromosomes. The results obtained for the Bahraini local sheep breeds are critical for the future genetic selection plan, as they will serve as a foundation for comparison with any future evolution.
Assessing the Awareness on Symptoms and Risk Factors of Stroke amongst Rural Community in Central Region of Malaysia: A Cross-Sectional Survey
Authors:   School of Graduate Studies, Management and Science University, Selangor, Malaysia, Nik Ramli Nik Nasihah , Genasan Deviga ,   International Medical School, Management and Science University, Selangor, Malaysia, Rossman Norzawani Shafika ,   International Medical School, Management and Science University, Selangor, Malaysia
Published: March 2024

Background: As the third leading cause of mortality in Malaysia, stroke is recognised as a medical emergency which requires urgent medical attention within a limited timeframe to prevent exacerbation of the brain damage and death in patients. Recent report revealed a high prevalence of pre-hospital delay amongst the stroke patients due to the lack of awareness on symptoms and risk factors of stroke, as well as poor understanding on appropriate action towards stroke. A number of studies had assessed stroke awareness amongst urban population residing in central region of Malaysia but yet amongst rural population. Methods: A cross-sectional survey was conducted amongst individuals residing in rural districts of Selangor by using a set of questionnaires assessing the sociodemographic characteristics, as well as the awareness and action towards stroke symptoms and risk factors. Results: All 343 respondents were able to recognise at least one modifiable risk factor for stroke. Meanwhile, only 36.44% were able to identify all the stroke symptoms. Despite majority of them were familiar with the stroke term, less than half of the respondents were aware of calling the emergency medical service as the appropriate action towards stroke symptoms. Conclusion: The present study indicated a poor level of awareness and action towards stroke symptoms and risk factors amongst rural population residing in Selangor.
Correlation of Serum Prolactin and Thyroid Stimulating Hormone Concentration in Infertile Women: A Systematic Review and Meta-Analysis
Authors:   Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia, Ramadras Delini Devi , Che Soh@Yusof Noor Azlin Azraini ,   Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia, Yaacob Najib Majdi ,   Unit of Biostatistics and Research Methodology, School of Medical Science, Universiti Sains Malaysia, Kelantan, Malaysia, Wan Azman Wan Norlina ,   Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia, Abdul Hamid Hanisah ,   Chemical Pathology Unit, Department of Pathology, Hospital Tengku Ampuan Rahimah, Selangor, Malaysia
Published: March 2024

Infertility affects millions of people of reproductive age worldwide. Thyroid hormones and prolactin (PRL) affect reproduction and pregnancy; therefore, these two hormones influence fertility. This systematic review and meta-analysis aimed to summarise the strength of the correlation between serum PRL and thyroid stimulating hormone (TSH) in infertile women and to explore selected factors influencing the correlation. We conducted a systematic search of online databases (PubMed, Scopus, ScienceDirect, SAGE and Google Scholar) from inception until March 2021 and a manual search of the bibliographies of the included studies to identify relevant publications. The original research paper describing the correlation between PRL and TSH in reproductive-age women with infertility (primary and secondary) was included. The risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Analytical Cross-Sectional Studies. A random effect model was used to estimate the pooled correlations of PRL and TSH, followed by an assessment of heterogeneity and a sensitivity analysis. From a total of 822 relevant articles identified, 11 were eligible and included in this systematic review and metaanalysis. The random effect pooled correlation estimates between PRL and TSH was 0.431 (95% CI: 0.251, 0.582), with substantial heterogeneity between the included studies (I2 = 80%, τ2 = 0.067, P < 0.001). No significant publication bias was observed. Study region, types of infertility, sample size and year of the study did not influence the correlation estimates. Our results highlighted a significant positive moderate correlation between serum PRL and serum TSH in infertile women.
A Qualitative Systematic Review of Healthcare Practitioners’ Experience of Workplace Violence
Authors:   Emergency Department, Hospital Sultan Idris Shah Serdang, Selangor, Malaysia, Md Emary Ezatul Alia , Mohd Arifin Siti Roshaidai ,   Department of Special Care Nursing, Kulliyah of Nursing, International Islamic University Malaysia, Pahang, Malaysia, Yusof Muhammad Zubir ,   Department of Community Medicine, Kulliyah of Medicine, International Islamic University Malaysia, Pahang, Malaysia
Published: March 2024

Healthcare practitioners face significant risks of workplace violence due to various reasons such as hospital congestion, miscommunication, and aggressive behaviours of patients and relatives. Exposure to workplace violence may disrupt the workflow process and compromise patient care in healthcare facilities, ultimately affecting job performance, reducing job satisfaction, and negatively affecting the physical and mental health of healthcare practitioners. This study aimed to review all the published studies conducted on the experiences of workplace violence among healthcare practitioners. This study is a systematic review of qualitative studies. Data were collected through online databases including ScienceDirect, PubMed, MEDLINE and JSTOR were searched from the year 2015–2021. The inclusion criteria were: qualitative methods and mixed methods of data collection and analysis; studies that were carried out among healthcare practitioners who have been experience on workplace violence; scope of the primary studies included experience of workplace violence; and published in English/Malay in academic journal between 2015 and 2021. A total of 15 papers were included in the final analysis. The overall quality of the included papers was high. Of the 15 papers, 12 studies fully met the CASP criteria. The results of the 15 included studies were organised into the thematic groups of: i) verbal violence as the common workplace violence; ii) perceived causes of workplace violence and iii) seeking help. Across different countries, verbal violence was the most common type of workplace violence reported by healthcare practitioners. This review also identified that a lack of information, failure to meet patient expectations, and delayed treatment were the main contributing factors to workplace violence.
Importance-Performance Analysis of Clinical Forensic Services Quality at Bhayangkara Hospital Pekanbaru, Indonesia
Authors:   Forensic Medicine and Medicolegal Department, Faculty of Medicine, Universitas Riau, Pekanbaru, Indonesia, Afandi Dedi ,   Master of Hospital Administration Study Program, Postgraduate Program, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia, Arini Merita ,   Master of Hospital Administration Study Program, Postgraduate Program, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia
Published: March 2024

Background: Service quality improvement efforts must focus on the utilisation of resources for continuous quality improvement. The importance-performance analysis (IPA) method is useful in finding service quality items that require corrective action. This study implemented the IPA method to obtain items that should be prioritised in improving the quality of a hospital’s clinical forensic services. Methods: A cross-sectional study of 284 clinical forensic patients at Bhayangkara Hospital, Pekanbaru, Indonesia was conducted. Self-administered and paper-based questionnaires, specifically the modified service quality (SERVQUAL)-based questionnaire, were used as the study instruments. Twenty-two service quality items were used as indicators and they were divided into five dimensions of service quality: i) reliability, ii) responsiveness, iii) assurance, iv) empathy and v) tangibility. The data were analysed using the IPA method. Results: The results showed that only seven items had a gap and a level of conformity that met the expectations of clinical forensic patients. Improvements in service quality should prioritise four items: i) providing a more private examination room for clinical forensic patients, ii) improving healthcare workers’ understanding of patient needs, iii) improving the readiness of healthcare workers to conduct examinations and iv) enhancing the clarity of information about examination procedures. Conclusion: The IPA method yielded several high-priority items that need to be improved; therefore, the hospital must focus on improving the quality of clinical forensic services.
„... nézz meg jobban a valóság én vagyok.” – avagy komplex környezetükben vizsgált kvalitatív adatok összefüggéseinek feltárása
Authors: Oláh Katalin
Published: March 2024

Recenzió. Sántha Kálmán (2022). Kvalitatív tartalomelemzés. Eötvös József Könyvkiadó.
Study on the evolution of buckling behavior of tubular string under frictional effects in horizontal wells
Authors: Wu Lianjie , Fang Pan , Huang Yun , Li Gao , Xu Ji
Published: March 2024

The buckling behavior of tubular string is critical for safe oil and gas resource development. In practical engineering, the buckling of tubular string can appear in different development phases, such as casing putting into wellbore, BHA drilling rock, pipeline buckling, etc. Therefore, in this paper, the buckling behavior and buckling evolution of the tubular string are explored considering friction in horizontal wells. By applying the principles of static equilibrium and beam-string theory, an established theoretical model is utilized to examine the buckling behavior of tubular string. The critical load for sinusoidal buckling is determined by using both the series and trial function methods, and a comparison is made between the results obtained from these two techniques. In addition, perturbation analysis is used to obtain the angular displacement's configuration function in the helical buckling post-buckling state. To validate the model's effectiveness, a comprehensive analysis of the numerical results is performed, considering both sinusoidal and helical buckling scenarios. The research findings demonstrate that both the series method and the trial function method can effectively analyze sinusoidal buckling with high accuracy. The presence of friction significantly impedes the buckling behavior of the tubular string. Moreover, friction’s influence causes a gradual decline in the efficiency of transmitting axial forces along the wellbore axis.
Scientific journals in the context of the transformation of international relations: Problems, challenges and prospects. Part 2
Authors:   Institute of Europe of the Russian Academy of Sciences, Lunkin Roman N. , Eom Gu Ho ,   Hanyang University, Degterev Denis A. ,   Peoples’ Friendship University of Russia named after Patrice Lumumba, Klemeshev Andrey P. ,   Immanuel Kant Baltic Federal University, Kuznetsova Tatiana Yu. ,   Immanuel Kant Baltic Federal University, Fedorov Gennadiy M. ,   Immanuel Kant Baltic Federal University
Published: March 2024

This review article has resulted from the discussion during the roundtable of the editors-in-chief of the international relations (IR) journals, convened by Saint Petersburg State University as part of the Congress of the IR students (November, 2022). The article traces the main changes in scientific activities of the IR journals under conditions of dramatic deterioration of Russia-West relations and subsequent re-orientation in terms of key topics, the authors’ affiliations, and other arising problems.
Shift-Share Method in Assessing the Interrelation of Employment Dynamics in Cities and Regions
Authors: Zalmanov I. A.
Published: March 2024

Purpose of the study. The aim of the study is to analyze the dynamics of employment in major cities of the Russian Federation, including megacities, in the context of rapid innovative development, complex demographic situation, and instability of external migration flows.

   The research focuses on identifying factors at various levels that affect employment, with an emphasis on the interconnections of cities and regions in the hierarchical “city-region” system.

   Materials and methods. The paper explores the shift-share method (SSM), which allows decomposing changes in employment with highlighting the influence of the overall dynamics of the regional labor market, industry characteristics, and competitive factors of cities. A multilevel analysis using this method aims to assess the structural-dynamic links of the hierarchically interconnected “city-region” system. The research uses municipal statistics data from 81 cities of the Russian Federation for the period from 2017 to 2021. Based on the concept of sectoral division of the economy, taking into account the functional features of the included industries, the structural-dynamic employment indexes in cities were analyzed across four economic sectors.

   Results. The application of the SSM method yielded results that allow for a detailed examination of employment dynamics in major cities. The analysis includes the influence of the overall dynamics of the regional labor market, industry characteristics, and competitive factors of cities. The research validates the effectiveness of the shift-share method for the preliminary analysis of employment dynamics in cities with the aim of specifying the significance of the impact on it by industrial and sectoral factors at regional and local levels and their prioritization for further analysis and the development of recommendations for urban economic management.

   Conclusion. The study highlights the importance of analyzing employment in the context of the urban economy, especially under conditions of rapid innovative development and demographic challenges. The SSM method appears to be an effective tool for preliminary examination of employment dynamics, identifying key factors, and developing management strategies aimed at improving the economic development of Russia’s major cities.
La Vieria Tehuelche, Aequipecten tehuelchus (D’ORB., 1846), del golfo de San José (Argentina): captación de postlarvas durante el colapso de la pesquería.
Authors: Ciocco Néstor Fernando , Monsalve María Alejandra
Published: March 2024

La vieira tehuelche del golfo San José, Argentina, ha soportado en los últimos 25 años una pesquería de relevancia regional (150-200 puestos de trabajo y 1-2,5 millones de (J$S/año). Dos relevamientos sistemáticos realizados a fines de 1995 y 1996 documentaron el colapso del efectivo disponible. La pesquería fue vedada a partir de la temporada 1996. Asociado a lo anterior, hubo un cambio dramático en el perfil de distribución de las poblaciones que podría tener efectos potencialmente descompensadores para la recuperación del stock. Con el objetivo de explorar la disponibilidad de larvas se fondearon en conjunto 96 colectores artificiales de postlarvas en 6 localidades del infralitoral superior del golfo San José durante las temporadas reproductivas 1995/96 y 1996/97. En cada estación se dispusieron 2 cuerdas de fondeo con 4 bolsas colectoras cada una: 2 a 2,5 m del fondo (nivel inferior) y 2 a 5 m del fondo (nivel superior). Los registros de captación (promedio 1995/96= 19,0 postlarvas/bolsa colectora) indican que la disponibilidad de larvas al iniciarse la veda de la pesquería era escasa y que transcurrido un año la captación (promedio 1996/97=216,8 postlarvas/bolsa colectora) aumentó significativamente, insinuando una incipiente recuperación que se manifestaría a nivel de tallas comerciales a partir de 1999. Los resultados sugieren que los efectos potencialmente descompensadores derivados del cambio dramático en el perfil de distribución de adultos estarían siendo contrarrestados por el aporte de los escasos núcleos de reproductores remanentes en el infralitoral superior y/o por adultos asentados a mayor profundidad.
Evaluación del crecimiento de juveniles de Lenguado Chileno (PARALICHTHYS ADSPERSUS, STEINDACHNER, 1867) cultivado en estanques.
Authors: Silva Alfonso , Oliva Marcia , Castelló Francesc
Published: March 2024

Para determinar la tasa de crecimiento en engorde de Paralichthys adspersus, la posible existencia de tasas de crecimiento diferenciales entre grupos y el tiempo que demora la especie en llegar a tamaño comercial en cultivo, se procedió a monitorear durante 19 meses a 1378 juveniles de lenguado los que fueron separados en tres grupos de acuerdo a su tamaño: Grandes (6,28 cm); Medianos (4,44 cm); Pequeños (3/31 cm). Los peces fueron puestos en tanques de 1 m2 a densidad inicial de 0,2 Kg/m2 con circulación de agua de mar filtrada (1 recambio/hora) y alimentados a saciedad 2 veces al día con pellet. Mensualmente semuestreó el 20% de los peces, determinándose su tasa de crecimiento específico, factor de condición, relación longitud-peso y ecuación de crecimiento. Tanto la tasa de crecimiento en longitud como en peso tienden a disminuir con la edad, no detectándose diferencias significativas entre grupos. Su relación longitud- peso describe un patrón de crecimiento con tendencia alométrica. Los parámetros de la función de crecimiento de von Bertalanffy obtenidos son L°° = 54,4 cm, k= 0,41 y to = 0,3638 años. De acuerdo a elloel 1er tamaño comercial se alcanzaría entre los 1,5 a 2 años y el kg a los 3,5 años de cultivo, tiempo que se acerca a otros peces planos de importancia comercial. Se concluye la inexistencia de diferencias significativas en la tasa de crecimiento entre los grupos de peces provenientes de un mismo desove.
Assessing the Probability of Affirmative Action Women’s Quota for Members of the Regional Representative Council (DPD)
Authors: Failaq Muhammad RM Fayasy , Monati Rahmatika
Published: March 2024

Gender quota policies for women in parliament or politics worldwide have developed since the 1990s. Indonesia applies this policy to the House of Representatives (DPR) as a political representation with a 30 (thirty) percent quota. As a fellow national parliamentary institution that is part of the People's Consultative Assembly (MPR), it turns out that there is a policy vacuum for DPD institutions. The vacuum, in addition to illustrating discriminatory practices, can potentially result in a very minimal representation of women in the institution. This study aims to assess the probability of implementing a similar policy for DPD institutions or provide other recommendations that are more appropriate. This research used normative legal research that uses the statute approach, conceptual approach, and comparative approach. Our data is obtained from a literature study and will be analyzed qualitatively. The results of this study, based on the consideration of nomination inequality and patriarchal culture, comparison of other countries, DPD as part of the MPR, Indonesia's bicameral system, and the correlation of Regional Representation and Women's Issues in Indonesia; DPD has several important and relevant arguments for implementing affirmative gender quota policy. However, against these considerations, there are also arguments that are not important and irrelevant, have no significant impact, or are impossible to apply, which is a challenge to implement affirmative policies such as DPR. Therefore, the most appropriate recommendation for DPD is simply through more massive socialization of candidacy by the General Election Commission (KPU) so that the legal culture in the form of awareness of the existence of female DPD members will grow and concerns about the lack of female DPD members can be prevented.
The significance and application of data analytics models for strategic management
Authors:   College of Computing and Informatics, Saudi Electronic University, Riyadh, Saudi Arabia, Ramzan Muhammad
Published: March 2024

In today's global landscape, the survival and success of organizations depend significantly on the effective use of their data assets for informed strategic decision-making. The exponential proliferation of data and its multiple uses present profound challenges and opportunities. Proficient management, processing, and use of this vast reservoir of data have emerged as a paramount concern in today's world. At the same time, the wise application of data analytics techniques and frameworks offers compelling strategic advantages. Identifying and deploying the most relevant data analytics methodologies within the realm of strategic management presents a formidable challenge for senior executives. This study examines the central role of data analytics in strategic decision-making and explores how organizations can leverage it to gain a competitive advantage. In addition, the research examines recent literature that sheds light on the various dimensions of integrating data analytics into strategic management. The study also provides selected illustrative use cases and instances of strategic management at the corporate, business, and functional levels. In particular, it presents a spectrum of both quantitative and qualitative data analysis techniques to underscore the availability of frameworks that facilitate the integration of data analysis into strategic management and decision-making processes.
XXVI Asamblea general de miembros activos : informe anual 2016
Authors:   ‎‎Corporación colombiana de investigación agropecuaria - AGROSAVIA
Published: March 2024

Al año 2.016 en Corpoica lo bautizamos “el año de creer en nosotros”. La razón de ese nombre fue la de reconocer que, durante los dos años anteriores, 2014 y 2015, tuvimos logros importantes que nos fortalecieron a niveles que no habíamos alcanzado históricamente, y que era hora, al interior de la organización, de reconocer y apalancarnos en dichos logros para consolidar nuestro modelo de gestión de conocimiento en redes. 2.016 entonces fue el año de dejar atrás las quejas y concentrarnos en lo estratégico.
Caracterización de micoinsecticidas para el control de Cerotoma tingomariana (Coleoptera: Chrysomelidae) y uso de un insecto modelo para evaluar su actividad biológica
Authors: Torres- orres Lissette , Espinel Correal Carlos , Grijalba Bernal Erika , García Riaño Lorena , Gelvez Pardo Ivonn , Santos Diaz Adriana
Published: March 2024

Beauveria bassiana (Bals.) Vuill. (Ascomycota: Cordycipitaceae) es una alternativa para el control de Cerotoma tingomariana (Bechyné) (Coleoptera: Chrysomelidae), una de las plagas de soya más limitantes en Colombia. Un granulado dispersable (WG) y un concentrado emulsionable (EC) a base del aislamiento Bv060, fueron caracterizados microbiológica, sicoquímica y biológicamente. Se establecieron límites de aceptación de estos y se estandarizó una metodología alterna para evaluar la actividad biológica utilizando como insecto modelo Chloridea (Heliothis) virescens (Lepidoptera: Noctuidae), mediante una prueba r&R. Los resultados obtenidos para cada parámetro permiten ser utilizados como referente en el control de calidad rutinario de estos micoinsecticidas. Antecedentes: Se seleccionó el aislamiento Bv060 de Beauveria bassiana por ocasionar 87,4 % de e cacia sobre adultos de C. tingomariana en laboratorio. Debido a su potencial, se desarrolló un granulado dispersable (WG) y un concentrado emulsionable (EC) a base de este hongo, pero es necesario determinar los criterios de calidad de estos micoinsecticidas. Objetivos: 1. Caracterizar tres lotes y establecer los límites de aceptación para los parámetros microbiológicos, sicoquímicos y biológicos de las dos formulaciones. 2. Estandarizar una metodología alternativa para la evaluación de la actividad biocontroladora de los formulados, utilizando como insecto modelo C. virescens debido a la dificultad en el establecimiento de la cría y la disposición constante de adultos de C. tingomariana. Hipótesis: 1. Los coeficientes de variación (CV) son inferiores al 10 %, indicando repetibilidad entre lotes, permitiendo el establecimiento de límites de aceptación. 2. Chloridea virescens se puede utilizar como insecto modelo para determinar la actividad biocontroladora de preformulados a base del aislamiento Bv060 de B. bassiana.