bluuebunny/crossref_metadata_2025 huggingface dataset:
Campus sexual assault and student activism, 1970–1990
Authors: Driessen Molly C
Published: April 2019

This historical analysis research project traces the early history of the anti-rape movement within the US by examining one university’s development of a sexual violence resource center and the role of student activism. The time period between the 1970s through the 1990s was selected for this analysis due to the significant development of legislation, research, and activism surrounding sexual violence on college campuses. In order to conduct this historical analysis, primary sources from the university’s Archives Collection were studied that included administrative documents, memos, financial documents, program reports, newspaper clippings, and training and workshop materials. Secondary sources were included to provide context to the topic of sexual violence, research, feminism, and campus culture during this time period. Amidst the university’s varied response and debates that surrounded sexual violence, the students’ persistent advocacy had led to conflict resolution.
Educational research, culturally distinctive epistemologies and the decline of truth
Authors: Horsthemke Kai
Published: April 2019

The assumptions underlying this contribution are, first, that educational research, like research in other fields, is expected to yield knowledge. This is rather uncontroversial. It is only when it comes to the definition of knowledge, the kinds of knowledge sought and to questions as to whose knowledge counts, that the debate characteristically becomes more heated. Second, and perhaps more controversially, a discussion of the nature and purposes of educational research will, at some stage, have to engage with the notion of truth. Despite having traditionally been a serious philosophical subject, the idea of truth has in recent times become rather unpopular, an idea non grata. The reconceptualisation of knowledge and the decline of truth are due in no small part to the increased popularity of certain kinds of postcolonial theory, postmodernism, constructivism and feminist thought, the rise of subaltern science and alternative epistemologies in academia. This article critically examines current trends in the theory of educational research: the case against ‘crypto-positivism’ and ‘hyperrationality’, and the trend in favour of ‘epistemological diversity’ and ‘critical constructivist epistemology’, especially against the backdrop of the decline of truth as a significant subject and yardstick that is currently exercising and restraining us, as educational researchers, philosophers and as persons.
Malignancy in Giant Cell Tumor of Bone: A Review of the Literature
Authors: Palmerini Emanuela , Picci Piero , Reichardt Peter , Downey Gerald
Published: April 2019

Background:

Primary and recurrent giant cell tumor of bone is typically benign; however, rarely giant cell tumor of bone can undergo malignant transformation. Malignancy in giant cell tumor of bone may be primary (adjacent to benign giant cell tumor of bone at first diagnosis) or secondary (at the site of previously treated giant cell tumor of bone). Malignant giant cell tumor of bone has a poor prognosis; it is important to distinguish malignant from benign lesions to facilitate appropriate management. The true incidence of malignant giant cell tumor of bone is not known, probably owing to inaccurate diagnosis and inconsistent nomenclature. We have analyzed current data to provide a robust estimate of the incidence of malignancy in giant cell tumor of bone.

Methods:

A literature search was performed to source published reports of primary and secondary cases of malignant giant cell tumor of bone. Studies that reported a denominator were used to estimate the incidence of malignancy.

Results:

We identified 4 large series of patients with malignant giant cell tumor of bone that provided data on 2315 patients with giant cell tumor of bone. Across these studies, the cumulative incidence of malignancy was 4.0%; the cumulative incidence of primary malignancy was 1.6% compared with 2.4% for secondary malignancy. Our analyses confirmed that most malignant giant cell tumor of bone is secondary and occurs following radiation. In addition, data from 8 small series showed that 4.8% of patients with giant cell tumor of bone who received radiation therapy developed secondary malignancy.

Conclusions:

Malignant giant cell tumor of bone is rare, and its identification is hindered by a lack of clear diagnostic criteria. For optimal care of patients with giant cell tumor of bone, we recommend: comprehensive histologic sampling to ensure accurate diagnoses; watchful follow-up, particularly for patients treated with radiation; and timely treatment of local recurrence.
Rare Case of Acute Type B Dissection Causing Complete Collapse of EVAR Stent
Authors: Ostapenko Alexander , Richard Michele N. , Dietzek Alan M.
Published: April 2019

We describe a unique case of an acute type B aortic dissection in a patient with a history of a previously placed infrarenal aortic stent for an abdominal aortic aneurysm. The patient presented with a hypertensive emergency and left lower extremity ischemia, and imaging revealed complete collapse of the previously placed stent graft with extension into the iliac limbs. He underwent emergent endovascular intervention. When the false lumen was entered by puncturing the dissection plane with a sheath, immediate reexpansion of the stent graft was observed. The entry point of the dissection was covered with 2 overlapping stents, restoring flow within the true lumen. Although aortic stent collapse from acute type B aortic dissections is extremely rare, we demonstrate that endovascular release of the outflow obstruction and depressurizing the false lumen can resolve this dreaded complication.
Systematic Review Investigating the Effects of Nonpharmacological Interventions During Sleep to Enhance Physical Rehabilitation Outcomes in People With Neurological Diagnoses
Authors: Johnson Brian P. , Shipper Andrea G. , Westlake Kelly P.
Published: April 2019

Objective. Conduct a systematic review of nonpharmacological interventions applied during sleep to enhance physical rehabilitation outcomes of individuals with a neurological diagnosis. Data Sources. Three online databases were searched for original research. Study Selection. Intervention studies were included that used outcome measures of impairment, activity, and/or participation. Data Extraction. Two reviewers independently screened 2287 titles and abstracts, reviewed 101 full texts, extracted data, and assessed study quality and risk of bias for 9 included studies. Data Synthesis. All included studies were randomized controlled trials involving continuous positive airway pressure (CPAP) with inpatient individuals with stroke and sleep apnea. Several studies also included long-term outpatient follow-ups. Results in terms of outcomes based on impairment, activity, and participation were mixed. However, several studies found that the use of CPAP following stroke and sleep apnea during early stroke recovery had benefits relative to no CPAP. Conclusions. The only nonpharmacological intervention to be administered during sleep in a neurological population to improve physical rehabilitation outcomes was found to be CPAP. This review was complicated by the variety of outcome measures used, lack of physical rehabilitation description, and CPAP compliance. In general, participants who had acceptable to good CPAP compliance saw the largest improvements in physical rehabilitation outcomes. Several other promising methods of brain stimulation during sleep are discussed.
Exploring factors affecting the severity of night-time vehicle accidents under low illumination conditions
Authors: Liu Jing , Li Jingyu , Wang Kun , Zhao Jianyou , Cong Haozhe , He Ping
Published: April 2019

Night-time vehicle accidents under low illumination conditions are frequent and serious, and they have attracted widespread attention. The objective of this study was to explore how various factors affect night-time vehicle accidents using data collected from a city in China. Combined with logistic model theory, the occurrence or absence of a night-time fatal accident was set as the dependent variable. A total of 10 variables, including the accident site, road type and road surface conditions, were selected as independent factors. Based on 2106 valid night-time vehicle accidents, a binomial logistic model was established to evaluate the impact of contributing factors on the severity of these accidents. The results show that the accident site, accident type and presence of a median divider are important factors that affect the severity of night-time vehicle accidents under low illumination conditions. The probability of fatal night-time accidents on road segments is 2.387 times that at intersections. The probabilities of fatal single-vehicle and vehicle–pedestrian night-time accidents are also greater than that of fatal vehicle–vehicle night-time accidents, by factors of 7.591 and 1.749, respectively. The probability of fatal night-time accidents on roads with median dividers is 3.273 times greater than that on roads without median dividers.
Efficacy of observational hand hygiene audit with targeted feedback on doctors’ hand hygiene compliance: A retrospective time series analysis
Authors: Smiddy Maura P , Murphy Olive M , Savage Eileen , Fitzgerald Anthony P , O’ Sullivan Brenda , Murphy Catriona , Bernard Margaret , Browne John P
Published: April 2019

Background:

Healthcare-associated infection compromises patient safety. Compliance with hand hygiene (HH) guidelines has been shown to be an effective method of reducing infection; however, it remains suboptimal and poorer among doctors compared to other healthcare workers. The aim of this study is to determine the relationship between an individualised observational hand hygiene audit (OHHA) and feedback intervention with observed HH compliance.

Methods:

We used a retrospective interrupted time series design using OHHA data from a five-year period, 2011–2015. OHHA indicated poorer HH compliance among doctors than other healthcare workers in a 345-bed acute private hospital. An increase in orthopaedic surgical site infection prompted additional auditing of the orthopaedic unit further identifying substandard HH compliance among orthopaedic surgeons. In addition to ongoing HH interventions, an individualised hand hygiene audit and feedback intervention focusing on consultant orthopaedic surgeons was implemented. Observed HH compliance improved. The intervention was then extended to include all consultant doctors at the study site. Audit was implemented by trained clinical nurse managers during clinical rounds. Written audit feedback was provided by the infection prevention and control team.

Results:

HH compliance increased significantly among both orthopaedic surgeons and other consultant doctors, P < 0.05.

Conclusion:

An individualised audit and feedback intervention was effective in improving compliance. Incorporation of OHHA with individualised feedback into routine daily practice needs to be considered as a quality improvement opportunity. This study has the potential to inform other audit and feedback interventions to maximise effectiveness and ensure implementation.
Data Governance and Stewardship
Authors: Dewey Bergren Martha
Published: April 2019

School nurses collect, manage, and report on school health data, which is covered by student privacy laws. School nurses and other district employees who collect and manage sensitive data must understand their responsibilities throughout the data life cycle. Nurses must identify who is accountable for data governance in their school and the process for influencing data governance policies and procedures. Every school district is accountable for the integrity and the security of the data it collects about students, families, and staff. Data governance encompasses all decisions about data throughout the data life cycle from defining what data are needed, to collecting, storing, protecting, using, sharing, and retiring and destroying data and who is accountable for those decisions. The data governance in schools is prescribed by the U.S. Department of Education, state education departments, and local school districts. The Student Privacy Policy Office at the U.S. Department of Education publishes clear and precise guidance on the treatment of data collected in schools.
Power of the Past, Celebrate the Present, Force of the Future–Part 5: A Look Into Our Next 50 Years . . .
Authors: Meadows Lynne P. , Bartholomew Kim , Major Keisha
Published: April 2019

The July 2018 issue of the NASN School Nurse, featured the first in a series of articles exploring the history, examining the present, and visioning the future of our organization in celebration of NASN’s 50th anniversary. While Parts 1 through 4 of this series focuses on the past and present, Part 5 is the first of two articles presenting the force of the future. In developing the content for Part 5, the authors posed a question to past and current NASN Officers, State Directors, and other school nursing colleagues. Areas of identified importance are grouped into the following major headings: research, education, collaboration, advocacy, image, technology, and leadership.
Is mutual recognition a viable general path for cooperation?
Authors: Satzger Helmut
Published: April 2019

In 1999, mutual recognition was declared to be the cornerstone of judicial cooperation not only, but also in criminal matters within the European Union (EU). Often this method seems to be regarded as a result of the close European integration and thus an invention of the EU. This article tries to show that even in traditional judicial assistance cases a similar trend could be witnessed and that mutual recognition is also applied – to a more or less intensive degree – in other regions and also in other areas of the law. In the author’s view, mutual recognition is a dynamic concept; its potential degree of realization depends on a number of contextual preconditions. As a result of the comparative view, he maintains that an ‘ordre public-proviso’ is a necessary ‘outlet’ and not at all outdated, especially in the context of judicial cooperation in criminal matters in the EU.
Expanding Visibility on Twitter: Author and Message Characteristics and Retweeting
Authors: Park Chang Sup , Kaye Barbara K.
Published: April 2019

Retweeting is not simply to get messages out to new audiences, but also to validate and engage with others. Using a content analysis of 3,429 tweets about the South Korean Anti-Terrorism Act of 2016, this study finds that the tweets created by civil society, political actors, and mass media/journalists are more likely to be retweeted than the tweets written by ordinary individuals, suggesting the role of heuristic strategy. This study also finds that content factors influence retweeting. Emotionally toned tweets are more likely to be retweeted, and rationality of tweets moderates the association between author types and retweeting.
Intergenerational co-residence during later life in Europe and China
Authors: Emery Tom , Dykstra Pearl A. , Djundeva Maja
Published: April 2019

Individuals in China are much more likely than Europeans to live with their adult children during later life. In this paper, we examine the extent to which this holds true across the diverse contexts and circumstances faced by Europeans and Chinese. We use comparative data from the Survey for Health, Ageing and Retirement in Europe and the China Family Panel Studies to examine cross-national differences in whom adults in later life choose to live with. We find that in rural China and among urban migrants there is a tendency to live with higher-educated children, whilst among urban Chinese and Europeans, individuals live with those with lower education levels. We also find that in Europe there is only a small preference for living with male adult children, whilst across China this preference is much stronger. However, we also note that this preference is weakest in urban China. These findings indicate strong differences in co-residence patterns between China and Europe, but also some similarities between specific subpopulations. We explain these differences and similarities using a social policy framework.
A Structural Equation Modeling Analysis of Parental Factors Underlying the Demand for Private Supplementary Tutoring in China
Authors: Liu Junyan
Published: April 2019

Purpose:

Private supplementary tutoring has been increasingly used by parents as part of wider strategies to assist their children’s education careers in China. With a theoretical lens of parentocracy, this article aimed to investigate the influential parental factors underlying the demand for private tutoring, focusing on parents’ socioeconomic resources and attitudes toward education.

Design/Approach/Methods:

This article drew upon data from the 2014 iteration of the China Family Panel Studies. Structural equation modeling (SEM) analysis was employed to explore the influences of parental factors.

Findings:

The SEM analysis confirmed that parental income, education, and aspirations on children’s education had both direct and indirect positive effects through the mediating factor of role construction on demand for tutoring. A multiple-group analysis was further conducted, and the difference in the patterns for urban and rural parents was explored. Parental occupation had no impact on demand for tutoring for rural parents but had both direct and indirect effects for urban parents. Both direct and indirect effects of household income on demand for tutoring were greater for urban parents than for rural parents.

Originality/Value:

This article examined the direct and indirect influences of parental factors on demand for private tutoring and explored the differences in patterns for urban and rural parents in a quantitative way. Findings have implications for education inequality.
Learning, Teaching, and Researching in Shadow Education in Hong Kong: An Autobiographical Narrative Inquiry
Authors: Yung Kevin Wai-Ho
Published: April 2019

Purpose:

This article aims to illustrate from the author’s insider perspective the lived experiences of engaging in private tutoring in Hong Kong as a tutee, a tutor, and a researcher and draw implications on several issues arising from the prevalence of shadow education.

Design/Approach/Methods:

This article adopted an autobiographical narrative approach. Data were collected through the author’s memoir of events, stimulated by the tutorial materials he used when he was a tutee and a tutor, his own video-recorded lessons of tutoring, and reflective journals from his research projects.

Findings:

Various issues are discussed based on the narrative of the author playing different roles in the tutoring industry, including (1) the positive and negative washback on mainstream education, (2) the lack of strict regulation of the quality of tutors and advertisements, and (3) how shadow education may exacerbate education inequality and how some tutorial companies and nonprofit organizations are addressing the issue.

Originality/Value:

This article, to the best of the author’s knowledge, is the only one that discusses the issues of shadow education from an author’s own personal experiences as a tutee, a tutor, and a researcher. It illustrates how practices and policies of the private tutoring industry are evolving in Hong Kong from an insider perspective.
Evolved Developmental Niche Provision Report: Moral Socialization, Social Thriving, and Social Maladaptation in Three Countries
Authors: Narvaez Darcia , Woodbury Ryan , Cheng Ying , Wang Lijuan , Kurth Angela , Gleason Tracy , Deng Lifang , Gutzwiller-Helfenfinger Eveline , Christen Markus , Näpflin Catherine
Published: April 2019

Evolutionary systems theory identifies niches as key developmental inheritances for animals. The human evolved developmental niche (EDN) is characterized by positive touch, responsiveness, play, and social togetherness and provides the responsive, relational dynamism that optimizes development. Cross-sectional and longitudinal studies of the human EDN have demonstrated correlations between degree of EDN consistency in early childhood and positive sociomoral development and avoidance of ill-being and misbehavior. We created a brief report of children’s recent EDN experience and examined its relation to child well-being and sociomoral development. Using samples from three cultures (United States, N=574; Switzerland, N=96; China, N=382), EDN provision in the past week was related to multiple child outcomes even after controlling for parental age, education, income, responsivity, and child gender. Factor analyses indicated three sets of latent factors in each sample: Moral Socialization, Social Maladaptation, and Social Thriving. Structural equation models indicated that EDN provision significantly predicted Social Thriving in all samples beyond control variables. EDN provision may be particularly helpful in predicting optimal social development.
Prevalence of dyspareunia and vulvodynia in a Colombian clinic sample: A pilot survey
Authors: Herrera Betancourt Ana Lucia , Bautista Katherine Enrique , Lopez-Jaramillo Jose Duvan , Lopez Isanoa Jorge Dario , Villegas-Echeverri Juan Diego , Lamvu Georgine
Published: April 2019

Objective:

The primary objective of our research was to determine the prevalence of dyspareunia and vulvodynia in a limited clinical sample of Colombian women.

Methods:

The study was composed of women who were seen in local Colombian medical clinics. A pilot survey was designed in Spanish to obtain patients’ demographic and medical history. Harlow’s validated questionnaire was incorporated into our survey to screen for dyspareunia and vulvodynia.

Results:

Five hundred and eighty-two women completed the survey and 96.2% (N = 560) reported being sexually active. The survey response rate was 96%. Among those who were initially screened and reported being sexually active, 51.8% (N = 290; 95% confidence interval: 47.7%–55.9%) described having pain with intercourse (dyspareunia) and 25.9% (N = 145; 95% confidence interval: 22.4%–29.7%) did not have pain. Of those who were sexually active, Harlow’s validated questionnaire was completed by 490 women: 27.6% (N = 135; 95% confidence interval: 23.7–31.75) described vulvar pain lasting longer than 3 months (vulvodynia); 51.9% (95% confidence interval: 43.1%–60.5%) had burning pain; 42.4% (95% confidence interval: 33.8%–51.0%) had sharp stabbing pain; 69.6% (95% confidence interval: 61.1%–77.2%) reported having pain during intercourse (dyspareunia).

Conclusion:

In this select population sample, the prevalence of dyspareunia ranged from 51.8% using a general survey to 69.6% using a validated questionnaire. The prevalence of vulvodynia was 27.6% (95% confidence interval: 23.7–31.75). This is higher than the prevalence of dyspareunia (45%) and vulvodynia (3%–16%) reported in the US general population.
The Sudden Development of Multi-Organ Lesions in a Patient With Pulmonary Sarcoidosis: A Case Report
Authors: Abdallah Mohamed A. , Ellithi Moataz , Sharma Rakshya , Cunningham Arwyn , Tantoush Hamza
Published: April 2019

Introduction. Sarcoidosis is a systemic granulomatous inflammatory disease that can involve almost any organ system in the human body. It most frequently presents with pulmonary infiltrates, hilar lymphadenopathy, and skin lesions. Clinical and subclinical involvement of other organ systems is not uncommon. However, the simultaneous development of clinically apparent multisystem sarcoidosis is very rare. Case Description. This 44-year-old Caucasian man presented to an outpatient clinic with a 2-month history of fatigue, night sweats, weight loss, loss of appetite, and mild abdominal discomfort. Initial laboratory finding showed elevated liver enzymes. Imaging studies revealed cirrhotic liver with steatosis, few enhancing hepatic masses, and multiple enlarged periaortic and portocaval lymph nodes. Liver biopsy revealed scattered necrotizing granulomatous hepatitis. Positron emission tomography scan showed extensive hepatic uptake, diffuse lymphadenopathy, as well as numerous fluorodeoxyglucose-avid osseous lesions. After extensive workup to rule out malignancy and infectious etiologies, a diagnosis of diffuse multi-organ sarcoidosis was made. He was ultimately treated with methotrexate and steroids, resulting in marked improvement in symptoms and liver function, with stable disease on repeat imaging. Conclusion. Diffuse multi-organ sarcoidosis is often associated with widespread lymphadenopathy and osseous lesions, which appear indistinguishable from malignancy on imaging. The angiotensin converting enzyme levels and inflammatory markers may be normal. Clinicians should be aware of the possibility of diffuse systemic sarcoidosis in any patient with a remote sarcoidosis history and the simultaneous development of multi-organ–related symptoms.
An Unusual Presentation of Merkel Cell Carcinoma in a HIV Patient: A Case Report and Literature Review
Authors: Ramachandran Preethi , Erdinc Burak , Gotlieb Vladimir
Published: April 2019

Merkel cell carcinoma (MCC) is a rare, rapidly growing, aggressive neuroendocrine skin cancer that generally arises on sun-exposed areas of body such as head, neck, upper limbs, and shoulders of people with light complexity. Typically, MCC presents as shiny, flesh-colored or bluish-red, intracutaneous nodule, possibly with ulceration or crusting. In most of the cases, there is an association with Merkel cell polyomavirus. Even though these are very aggressive tumors, early detection and treatment has always given favorable outcome. There seems to be no consensus in definite prognostic markers, and advanced stages have the worst outcome even with treatment. There has been a recent trend in using PD-I/PD-L1 target therapy rather than chemotherapy in these cancers and have shown to improve survival by many months. In this article, we report a very unusual presentation of MCC first found on left frontoparietal skull as an 8-cm diameter fixed, subcutaneous mass without any typical features of MCC and was found to have metastatic spread to lung and liver. The patient was treated with palliative radiotherapy to brain and chemotherapy with cisplatin/etoposide with addition of immunotherapy later.
The Role of S100B Protein at 24 Hours of Postnatal Age as Early Indicator of Brain Damage and Prognostic Parameter of Perinatal Asphyxia
Authors: Luo Qiu , Pin Tamis , Dai LiFen , Chen GuiXian , Chen YuTong , Tian FuLu , Zhang Man
Published: April 2019

Introduction. S100B protein is a cytosolic calcium-binding protein with a molecular weight of 21 kDa, which is present in various cells and concentrated mainly in the glial cells, which play a vital role in the maintenance of cellular homeostasis in the central nervous system. It is possible that increased S100B protein level might be considered as sensitive and specific indicator to predict early brain damage. Aim. To investigate the prognostic value of serum S100B protein in neonates with perinatal asphyxia (PA) at 24 hours of postnatal age. Methods. A systematic review was performed. Inclusion criteria were studies including data of neonates with PA, monitored with serum S100B, and with neurodevelopmental follow-up of at least 2 weeks. The period of bibliographic search was until January 2017. The consulted databases were MEDLINE, PsycINFO, and Embase. A combination of the following subject headings and keywords was adapted for each electronic database: “perinatal asphyxia,” “hypoxic ischemic encephalopathy,” “hypoxia-ischemia, brain,” and “S100B.” Meta-Disc1.4 software was used. Results. From the 1620 articles initially identified, 6 were finally included and reviewed. The overall diagnostic sensitivity of serum S100B was 0.80 (95% confidence interval [CI] = 0.68-0.88) and the specificity was 0.79 (95% CI = 0.70-0.87). But there was lower predictability value, that is, the positive likelihood ratio was only 3.26 (95% CI 1.74-6.12) and the negative likelihood ratio was 0.32 (95% CI = 0.20-0.5). The diagnostic odds ratio was 12.40 (95% CI = 4.66-33.0). Conclusion. Increased serum S100B level at 24 hours of postnatal life can demonstrate brain damage, but it should not be the only one used to predict PA outcome.
Extension for Community Healthcare Outcomes Uruguay: A New Strategy to Promote Best Primary Care Practice for Autism
Authors: Giachetto Gustavo , Casuriaga Ana Laura , Santoro Anabella , Kanopa Virginia , Garrido Gabriela , Fernández José , Cohen Henry , Sohl Kristin
Published: April 2019

Introduction. In Uruguay, the special care required for children with neurodevelopmental disorders presents difficulties including lack of access to specialists and rehabilitation services. Project ECHO (Extension for Community Healthcare Outcomes) connects primary care clinicians from remote areas to specialists to enable them to treat complex conditions through ongoing education and mentoring. Objective. To share the experience of the ECHO Autism program during the first 2 years of implementation. Methods. Analysis of ECHO Autism clinics from June 2015 to June 2017 including clinical cases presented participants’ self-perception of changes in skills and competences. Results. Twenty clinical cases were presented: mean age 4.5 years; 15 were males; and 17 with medical and psychiatric comorbidities. After ECHO Autism implementation, a statistically significant improvement in participants’ self-perception of skills and competences was observed. Conclusions. ECHO Autism in Uruguay is a meaningful approach to autism care and offers improved access to best practice care.
Assessing Impact of Employer Branding on Job Engagement: A Study of Banking Sector
Authors: Rana Geeta , Sharma Ravindra
Published: April 2019

The purpose of this study is to investigate the impact of employer branding practices on job engagement in banking sector of Uttarakhand. Further, based on the existing literature, only five employer branding practices (interest value, social value, development value, application, and economic value) which are widely accepted in banking sector has selected for present study. By using convenience sampling, data were collected from 245 employees, who are working in the banks in Uttarakhand districts. EFA, CFA, and SEM statistical techniques were used to analyze the data. Further, reliability and validity tests were also performed. Findings of this study revealed that employer branding practices such as interest value, social value, development value, and economic value positively affect the job engagement. When employees perceive the workplace as interesting, socially supportive, and filled with creative value, they undergo growth and advancement which develop employee confidence and satisfaction; further, they are simultaneously engaged with their jobs. The study is cross-sectional in nature and only focus on job engagement. For future research, employee’s level of commitment and organizational attractiveness need to be explored. This study is highly beneficial for employees, corporate practitioners, academicians and researchers for guidelines and policies implementations of employer branding practices.
Bad Loans of Public Sector Banks in India: A Panel Data Study
Authors: Ramesh Kandela
Published: April 2019

The soundness of the banking system is necessary for economic advancement and financial stability. In the contemporary era, the Indian banking system has suffered from the accumulation of substantial non-performing assets (NPAs), especially in the public sector banks (PSBs). This article examines the financial determinants of bad loans in the Indian PSBs with the help of panel data regression analysis. Panel dataset of 21 Indian PSBs for eight years from 2010 to 2017 is used for the study. For analysis, net non-performing assets (NNPAs) as a dependent variable and financial indicators as independent variable are used. Using the random effect model, it is found that credit–deposit ratio, loan maturity, and return on assets have a negative relationship with NNPAs. These factors have an association with a lower level of NPAs. Operating expenses and capital adequacy ratio have an insignificant effect on NNPAs. On the other hand, factors such as priority sector loans, collateral values, and non-interest income have a positive impact on NNPAs. These factors are an indication of a higher level of bad loans and are adding to the accumulation of NPAs in PSBs.
Unusual Presentation of Groin Sarcoma Involving the Common Femoral Artery: A Case Report
Authors: Carrillo J. Valeria
Published: April 2019

Sarcomas are characterized by innumerable clinical presentations. Sarcoma tumors involving peripheral vessels are quite rare and not always easy to identify despite the availability of diagnostic tools such as sonography, computed tomography (CT), and magnetic resonance imaging (MRI). This case report discusses the imaging findings of angiography, sonography, and CT, which were the modalities used in this case. Initially, the patient underwent limited duplex ultrasound and CT imaging to evaluate a painful right groin area after right common femoral artery (CFA) angioplasty and laser atherectomy, with left groin access. Sonographic findings demonstrated a large, heterogenous, hypoechoic, and avascular mass surrounding the right CFA. CT imaging of the pelvis described a partially thrombosed pseudoaneurysm surrounding the CFA. Surgical evacuation of what was believed to be a hematoma was performed; a pathology report revealed sarcoma of the groin.
Critical Success Factors Affecting Project Performance: An Analysis of Tools, Practices, and Managerial Support
Authors: Jitpaiboon Thawatchai , Smith Sheila M. , Gu Qiannong
Published: April 2019

This study examines success factors for a team project. The influence of three success factors—(1) project management tools, (2) project management best practices, and (3) managerial support on the performance of individuals, teams, and projects was measured. We surveyed 121 business students with team project experience. Exploratory factor analysis confirms that success factors (project management tools, project management best practices, and managerial support) in a project tend to respond more to individual team members’ performance compared to team performance and project performance. Our findings indicate that project management tools, project management best practices, and support are equally important to success during project implementation. We also find that harmonious relationships among team members lead to extrinsic motivation within project teams and enhance team and project performance. However, most of the time, the system—not the individual—causes a project to fail. Therefore, this study suggests that project managers make a clear plan and agenda by utilizing project management tools.
Development of a social media-based intervention targeting tobacco use and heavy episodic drinking in young adults
Authors: Ramo Danielle E. , Meacham Meredith C. , Kaur Manpreet , Corpuz Ella S. , Prochaska Judith J. , Satre Derek D.
Published: April 2019

Background

Tobacco use and heavy episodic drinking (HED) commonly co-occur in young adults. We developed and tested usability of the Smoking Tobacco and Drinking (STAND) intervention for young adults delivered on Facebook.

Methods

To inform the intervention, focus groups were held with 25 young adults age 18 to 25 (12% female; Mean age = 20.4) who smoked cigarettes and reported at least one HED episode in the past month. Facebook intervention posts (N = 180) were tailored to readiness to quit smoking, and tested in two private Facebook behavioral change groups (Ready, Not Ready) with N = 29 young adults (10% female; Mean age = 20.8). Participants flagged posts in need of change, and we assessed engagement (comment frequency).

Results

Focus groups revealed preference for changing one substance at a time and greater receptivity to quitting smoking than reducing drinking. Mean comments per post were 5.3 (SD = 1.1) in Ready groups and 11.7 (SD = 5.1) in Not Ready groups; 94/180 (52.2%) posts were flagged for change. The level of engagement and the flagging of posts for change did not differ by group or by whether the post targeted tobacco, alcohol, or both substances combined (all p > .10). Overall, STAND was rated as easy to understand, providing sound advice, worthy of recommendation, and helpful (all agreement 100% among Ready; 50–70% among Not Ready).

Conclusions

The current findings informed development of a social media-based intervention targeting tobacco and alcohol use in young adults. Although there was greater interest in making changes in smoking than drinking behavior, receptivity and acceptability of the Facebook post messages in the STAND intervention was high overall. The intervention is being further refined for evaluation in a larger trial.

Trial registrationName of the registry Smoking Tobacco and Drinking Study (STAND); Trial registration number NCT03163303; Date of registration 5/23/17; URL of trial registry recordhttps://clinicaltrials.gov/ct2/show/NCT03163303.
Introduction to this special section: India
Authors: Chacko Soman , Rath Satchidananda , Sen Pranab , Das Subrata Kumar
Published: April 2019

India is currently the third-largest global consumer of petroleum products after the United States and China. The country produces approximately 720,000 barrels of crude oil and 3.16 billion ft3 of gas per day and imports more than 80% of its oil and 50% of its gas needs. This large discrepancy between domestic supply and consumption has been rising rapidly of late. With an economy growing at 6%–8% per year, India's energy demand growth over the next couple of decades is forecast to be among the highest in the world. To mitigate the heavy dependence on imported energy, India has stepped up efforts in recent years to increase domestic production of oil and gas.
Fatehgarh lacustrine turbidite potential, Barmer Basin, India
Authors: Chatterjee Priyabrata , Kuila Utpalendu , Naidu B. N. S. , Bora Hriday Jyoti , Malkani Anil , Dutta Sandipan , Mandal Arpita , Mishra Premanand , Mohapatra Pinakadhar
Published: April 2019

Global discovered resources of oil and gas in giant stratigraphic and structural-stratigraphic combination traps have increased by nearly 50% in the last 17 years. Among the biggest contributors are the large discoveries in deepwater turbidite systems in passive margins and rift basins. The current study area is located in the Barmer Basin in northwestern India. Barmer Basin is a prolific petroliferous basin with major oil discoveries in structural plays including Mangala, Bhagyam, and Aishwariya fields. The principal reservoirs in the structural highs are high-quality fluvial sandstones of the Paleocene Fatehgarh Formation. Lacustrine turbidite plays have been discovered in the overlying Paleocene Barmer Hill Formation, albeit with moderate to poor reservoir quality. The potential exists, however, for finding off-structure lacustrine deepwater turbidite plays in the Paleocene Fatehgarh with reservoir quality comparable to the high-quality fluvial facies encountered updip in the structural plays. An integrated approach was adopted to identify stratigraphic entrapments across the basin to chase high-quality Fatehgarh reservoirs. Gross depositional environment maps integrating new geoscientific data were created, followed by well-calibrated seismic geomorphology and seismic facies interpretations to identify the distal lacustrine deepwater turbidite system fed by the updip fluvial Fatehgarh systems. Worldwide, the critical risk elements associated with such plays are reservoir presence, quality, and lateral seal. Geophysical tools like unsupervised seismic waveform classification, spectral decomposition, and seismic inversion were applied to the available seismic data, and the results were integrated with the regional geology and well facies information to derisk the critical risk segments.
Z-Transferred Discrete-Time Infinite Impulse Response Filter as Foundation–Soil Impedance Function for SDOF Dynamic Structural Response Considering Soil–Structure Interaction
Authors: Sung Yu-Chi , Chen Chieh-Cheng
Published: April 2019

This paper proposed a novel dynamic structural analysis of a single-degree-of-freedom system considering soil–structure interaction (SSI). The z-transferred discrete-time infinite impulse response filter serving as a foundation–soil impedance function to get a transfer function between the ground displacement and foundation shear was proposed first. The corresponding time history of the foundation shear caused by a specific input of ground displacement can be determined through the filter obtained, and the succeeding structural responses are then able to be found by the base force propagating function. Case studies comparing the structural dynamic response with and without SSI were carried out. Without consideration of SSI, there was an overestimation of structural displacement for the structure with a shorter period, but in contrast to that, an underestimation for the structure with a longer period was concluded based on the results obtained.
Phase II Study of Lenvatinib in Patients With Progressive, Recurrent or Metastatic Adenoid Cystic Carcinoma
Authors: Tchekmedyian Vatche , Sherman Eric J. , Dunn Lara , Tran Crystal , Baxi Shrujal , Katabi Nora , Antonescu Cristina R. , Ostrovnaya Irina , Haque Sofia S. , Pfister David G. , Ho Alan L.
Published: April 2019

PURPOSE

Recurrent or metastatic adenoid cystic carcinoma (R/M ACC) is a malignant neoplasm of predominantly salivary gland origin for which effective therapies are lacking. We conducted a phase II trial evaluating the multitargeted tyrosine kinase inhibitor lenvatinib in patients with R/M ACC.

PATIENTS AND METHODS

This study was conducted with a two-stage minimax design. Patients with histologically confirmed R/M ACC of any primary site with radiographic and/or symptomatic progression were eligible. Any prior therapy was allowed except previous lenvatinib. Patients received lenvatinib 24 mg orally per day. The primary end point was overall response rate. Secondary end points were progression-free survival and safety. An exploratory analysis of how MYB expression and genomic alterations relate to outcomes was conducted.

RESULTS

Thirty-three patients were enrolled; 32 were evaluable for the primary end point. Five patients (15.6%) had a confirmed partial response, 24 patients (75%) had stable disease, two patients (6.3%) discontinued treatment as a result of toxicity before the first scan, and one patient (3.1%) had progression of disease as best response. Median progression-free survival time was 17.5 months (95% CI, 7.2 months to not reached), although only eight progression events were observed. Patients otherwise were removed for toxicity (n = 5), as a result of withdrawal of consent (n = 9), or at the treating physician’s discretion (n = 6). Twenty-three patients required at least one dose modification, and 18 of 32 patients discontinued lenvatinib for drug-related issues. The most common grade 3 or 4 adverse events were hypertension (n = 9; 28.1%) and oral pain (n = 3; 9.4%). Three grade 4 adverse events were observed (myocardial infarction, n = 1; posterior reversible encephalopathy syndrome, n = 1; and intracranial hemorrhage, n = 1).

CONCLUSION

This trial met the prespecified overall response rate primary end point, demonstrating antitumor activity with lenvatinib in R/M ACC patients. Toxicity was comparable to previous studies, requiring monitoring and management.
Dose-Adjusted EPOCH-R Compared With R-CHOP as Frontline Therapy for Diffuse Large B-Cell Lymphoma: Clinical Outcomes of the Phase III Intergroup Trial Alliance/CALGB 50303
Authors: Bartlett Nancy L. , Wilson Wyndham H. , Jung Sin-Ho , Hsi Eric D. , Maurer Matthew J. , Pederson Levi D. , Polley Mei-Yin C. , Pitcher Brandelyn N. , Cheson Bruce D. , Kahl Brad S. , Friedberg Jonathan W. , Staudt Louis M. , Wagner-Johnston Nina D. , Blum Kristie A. , Abramson Jeremy S. , Reddy Nishitha M. , Winter Jane N. , Chang Julie E. , Gopal Ajay K. , Chadburn Amy , Mathew Susan , Fisher Richard I. , Richards Kristy L. , Schöder Heiko , Zelenetz Andrew D. , Leonard John P.
Published: April 2019

PURPOSE

Alliance/CALGB 50303 (NCT00118209), an intergroup, phase III study, compared dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (DA-EPOCH-R) with standard rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) as frontline therapy for diffuse large B-cell lymphoma.

PATIENTS AND METHODS

Patients received six cycles of DA-EPOCH-R or R-CHOP. The primary objective was progression-free survival (PFS); secondary clinical objectives included response rate, overall survival (OS), and safety.

RESULTS

Between 2005 and 2013, 524 patients were registered; 491 eligible patients were included in the final analysis. Most patients (74%) had stage III or IV disease; International Prognostic Index (IPI) risk groups included 26% IPI 0 to 1, 37% IPI 2, 25% IPI 3, and 12% IPI 4 to 5. At a median follow-up of 5 years, PFS was not statistically different between the arms (hazard ratio, 0.93; 95% CI, 0.68 to 1.27; P = .65), with a 2-year PFS rate of 78.9% (95% CI, 73.8% to 84.2%) for DA-EPOCH-R and 75.5% (95% CI, 70.2% to 81.1%) for R-CHOP. OS was not different (hazard ratio, 1.09; 95% CI, 0.75 to 1.59; P = .64), with a 2-year OS rate of 86.5% (95% CI, 82.3% to 91%) for DA-EPOCH-R and 85.7% (95% CI, 81.4% to 90.2%) for R-CHOP. Grade 3 and 4 adverse events were more common ( P < .001) in the DA-EPOCH-R arm than the R-CHOP arm, including infection (16.9% v 10.7%, respectively), febrile neutropenia (35.0% v 17.7%, respectively), mucositis (8.4% v 2.1%, respectively), and neuropathy (18.6% v 3.3%, respectively). Five treatment-related deaths (2.1%) occurred in each arm.

CONCLUSION

In the 50303 study population, the more intensive, infusional DA-EPOCH-R was more toxic and did not improve PFS or OS compared with R-CHOP. The more favorable results with R-CHOP compared with historical controls suggest a potential patient selection bias and may preclude generalizability of results to specific risk subgroups.
The N-end rule pathway and Ubr1 enforce protein compartmentalization via P2-encoded cellular location signals
Authors: Tran Anthony
Published: April 2019

The Arg/N-end rule pathway and Ubr1, a ubiquitin E3 ligase conserved from yeast to humans, is involved in the degradation of misfolded proteins in the cytosol. However, the root physiological purpose of this activity is not completely understood. Through a systematic examination of single-residue P2-position mutants of misfolded proteins, and global and targeted bioinformatic analyses of the Saccharomyces cerevisiae proteome, it was determined that Ubr1 preferentially targets mistranslocated secretory and mitochondrial proteins in the cytosol. Degradation by Ubr1 is dependent on the recognition of cellular location signals that are naturally embedded into the second amino acid residue of most proteins. This P2-encoded location signaling mechanism may shed light on how Ubr1 and the N-end rule pathway are involved in neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. A corollary to this discovery is that the N-end rule pathway enforces the compartmentalization of secretory and mitochondrial proteins by degrading those that fail to reach their intended subcellular locations. The N-end rule pathway is therefore likely to have been critical to the evolution of endosymbiotic relationships that paved the way for advanced eukaryotic cellular life.

This article has an associated First Person interview with the first author of the paper.