bluuebunny/crossref_metadata_2025 huggingface dataset:
Accuracy of Implant Placement Based on Three-Dimensional Preoperative Planning in Total Elbow Arthroplasty
Authors: MATSUO Tomoki , IWAMOTO Takuji , KIYOTA Yasuhiro , SUZUKI Taku , MATSUMURA Noboru , SATO Kazuki
Published: August 2024

Background: Accurate implant placement in the optimal position is important to obtain favourable clinical outcomes and prevent complications in total joint arthroplasty. We aimed to assess the accuracy of implant placement based on three-dimensional (3D) preoperative planning for unlinked total elbow arthroplasty (TEA) and to clarify the effect of implant placement on clinical outcomes.

Methods: This study included 20 patients (22 elbows, 17 with rheumatoid arthritis and 5 with osteoarthritis, with a mean follow-up period of 47 months) who underwent TEA with an unlinked-type implant after computed tomography (CT)-based 3D preoperative planning. Implant placement was planned preoperatively and several parameters were set to reflect it intraoperatively. TEA was performed based on the plan, and postoperative CT was conducted to evaluate differences in implant placement by comparing the preoperative plan and postoperative implant placement. Furthermore, we evaluated the relationship between implant placement differences and postoperative clinical outcomes, including range of motion, Visual Analogue Scale, Mayo Elbow Performance Score 1 year after surgery and complications at the last follow-up.

Results: The mean absolute translation was within 2 mm, the mean absolute tilt was within 4°, the mean absolute rotation of the humeral component was within 4° and the mean absolute rotation of the ulnar component was 10.2° ± 6.8°. In the ulnar components, 15/22 (68%) cases were externally rotated, and the mean external rotation was 7.1° ± 10.2°. We defined the absolute ulnar component’s rotational difference of more than 10° as a ‘malrotation’ group (n = 8) and 10° or less as a ‘control’ group (n = 14). We compared the clinical outcomes between both groups, however, no significant differences were observed in clinical outcomes and complications.

Conclusions: We observed notable malrotation in the postoperative positioning of the ulnar component. Intraoperative support devices may be necessary to accurately reproduce the preoperative plan in the surgical field.

Level of Evidence: Level IV (Therapeutic)
Energy expenditure during physical work in cold environments: physiology and performance considerations for military service members
Authors: Schafer Erica A. , Chapman Christopher L. , Castellani John W. , Looney David P.
Published: August 2024

Effective execution of military missions in cold environments requires highly trained, well-equipped, and operationally ready service members. Understanding the metabolic energetic demands of performing physical work in extreme cold conditions is critical for individual medical readiness of service members. In this narrative review, we describe 1) the extreme energy costs of performing militarily relevant physical work in cold environments, 2) key factors specific to cold environments that explain these additional energy costs, 3) additional environmental factors that modulate the metabolic burden, 4) medical readiness consequences associated with these circumstances, and 5) potential countermeasures to be developed to aid future military personnel. Key characteristics of the cold operational environment that cause excessive energy expenditure in military personnel include thermoregulatory mechanisms, winter apparel, inspiration of cold air, inclement weather, and activities specific to cold weather. The combination of cold temperatures with other environmental stressors, including altitude, wind, and wet environments, exacerbates the overall metabolic strain on military service members. The high energy cost of working in these environments increases the risk of undesirable consequences, including negative energy balance, dehydration, and subsequent decrements in physical and cognitive performance. Such consequences may be mitigated by the application of enhanced clothing and equipment design, wearable technologies for biomechanical assistance and localized heating, thermogenic pharmaceuticals, and cold habituation and training guidance. Altogether, the reduction in energy expenditure of modern military personnel during physical work in cold environments would promote desirable operational outcomes and optimize the health and performance of service members.
Neural and muscular contributions to the age-related differences in peak power of the knee extensors in men and women
Authors: Wrucke David J. , Kuplic Andrew , Adam Mitchell D. , Hunter Sandra K. , Sundberg Christopher W.
Published: August 2024

The greater age-related loss in power relative to the loss in muscle mass of the knee extensors was primarily due to factors altering the contractile properties of the muscle for both old and very old (≥80 yr) adults. The mechanisms for the decrements in power with aging appear largely similar for men and women, although neural factors may play more of a role in older women.
Combining Gene Expression Data with GWAS Highlights the Causal Gene CCDC25 as a Biomarker for a Favorable Prognosis in Colorectal Cancer
Authors: Zhang Guowei , Ma Yuling , Shao Jianfeng , Ke Caiping , Li Chunhua , Dong Yaping
Published: August 2024

Background. Coiled‐coil domain containing 25 (CCDC25) is a receptor for neutrophil extracellular trap (NET) DNA and is involved in various cancers, including CRC. This study aimed to investigate the regulatory role of CCDC25 in CRC using GWAS data, eQTL, transcriptomic profiles, and clinical information of CRC patients. Methods. From open‐source databases, GWAS summary data, eQTL expression profiles, and transcriptomic profiles, as well as clinical information were collected for CRC patients. Mendelian randomization (MR) was used to investigate the causal relationship between CCDC25 and CRC risk. The expression of CCDC25 and its associated differentially expressed genes (DEGs) were identified. We explored the relationship between CCDC25 expression and survival, biological functions, immune cell infiltration, immune checkpoint expression, and response to immunotherapy. Results. High CCDC25 expression reduces the risk of CRC. CCDC25 is downregulated in various cancers, particularly in CRC tumor tissues compared to normal tissues. Metabolic pathways are enriched in groups with high CCDC25 expression, while cancer‐related pathways are enriched in groups with low CCDC25 expression. High CCDC25 expression is also associated with increased infiltration of resting memory CD4+ T cells, elevated levels of most immune checkpoints, and an enhanced response to anti‐PD1 therapy. In addition, 95 DEGs were identified between high‐CCDC25 and low‐CCDC25 groups, and eight genes (FDFT1, ASAH1, ADAM9, CXCL14, SERPINA1, NAT1, EREG, and GSR) were identified as prognostic genes. Conclusion. CDC25 might serve as a candidate diagnostic and prognostic marker for CRC patients.
Evaluating the Economic Feasibility of Combined Biochar, Lime, and Inorganic Fertilizer Rates for Garlic (Allium sativum L.) Production in Gimbi District, Western Ethiopia
Authors: Kenea Solomon Abeba , Abera Goshu Tolera , Chimdessa Kinati
Published: August 2024

Garlic is one of the most significant vegetable crops; however, western Ethiopian agricultural land soils are limited by acidic soil, and garlic yield and profit margins continue to be low. The objective of the current experiment was to determine whether the economic viability of garlic production in Gimbi, Western Ethiopia, could be supported by the simultaneous application of biochar, lime, and inorganic fertilizer. The experiment comprised 14 treatments laid out in a RCBD with 3 replicates. The use of combined coffee husk biochar (CHB), soil test‐based value lime (STV), and inorganic fertilizer (NPSB) rates at comb4 and comb11, respectively, resulted in the maximum net benefit costs of 955,461.25 ETB ha−1 in farm 1 and 1,086,776.22 ETB ha−1 in farm 2, whereas costs were incurred with total variable costs of 21,317.75 ETB ha−1 and 16,038.78 ETB ha−1, respectively. The treatments with the highest marginal rates of return in farms 1 and 2 were those that included CHB, STV, and NPSB at comb4 (marginal rate of return = 266,932.80%) and comb12 (marginal rate of return = 29,558.12%), respectively. The difference in economic benefit may have originated from the soil buffer capacity response to ameliorant rates, as the soils of farms 1 and 2 were strongly acidic and very strongly acidic soils. This variation influences plant nutrient uptake, biomass yield, and yield components by enhancing the fertility characteristics of the soil. Therefore, the combined CHB, STV, and NPSB rates at comb4 per hectare in strongly acidic soils and comb12 per hectare in very strongly acidic soils could result in the highest economic return rate for the production of garlic and improve soil fertility. Since only two locations were studied, multilocation research is needed to give a firm recommendation.
Construction and Validation of a Novel Prognostic T‐Cell Exhaustion‐Related ceRNA Network in Lung Adenocarcinoma
Authors: Ye Hua , Yu Wenwen , Bao Xiaoqiong , Ni Yangyang , Zhou Weilong , Li Yunlei , Chen Xiangxiang , Li Jifa , Zheng Long
Published: August 2024

Background. T cell exhaustion (TEX) is a state of T cells that is characterized by poor function of effectors and increased expression of inhibitory signals. However, the heterogeneity and prognostic values of TEX in lung adenocarcinoma (LUAD) remain not fully understood. Methods. Based on the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) transcriptomic profiles, we screened differentially expressed lncRNAs, miRNAs, and mRNAs and identified differentially expressed TEXs. Univariate cox and LASSO regression analyses were performed to construct TEX‐related prognostic signature and risk score and validated their expression using real‐time PCR assay. We then investigated the potential mechanism, immune landscape, and antitumor therapy response in LUAD. Results. A total of 315 DE‐lncRNAs, 161 DE‐miRNAs, and 2589 DEGs were screened, and then 80 DE‐TEXGs were identified in LUAD. Based on univariate cox and LASSO regression analyses, CCNA2 and SLC2A1 were identified as TEX‐related prognostic signatures, and the risk score subsequently was calculated. LUAD patients were divided into high‐ and low‐risk groups, and high‐risk groups were involved in poor survival status, immunosuppression, and more sensitive to anti‐CTLA4 therapy. Finally, a TEX‐related ceRNA network was constructed and validated based on DE‐lncRNAs, DE‐miRNAs, and TEX‐related prognostic signatures. Conclusion. We constructed the TEX‐related prognostic signature and its relevant ceRNA network and discovered the molecular mechanism and prognostic values of TEX in LUAD.
Supplementary Table S7 from The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors
Authors: Heath Hannah , Yoo Jin Y. , Akter Sabrina , Jain Atharva , Sharma Vani , McGee Hannah , Soliman Aiman , Mahmoud Abeer M. , Matthews Alicia K. , Winn Robert A. , Madak-Erdogan Zeynep , Kim Sage J.
Published: August 2024

Pathway analysis results of cluster 6 genes from Supplementary Figure 4C.
Supplementary Figure 1 from Noninvasive Lung Cancer Subtype Classification Using Tumor-Derived Signatures and cfDNA Methylome
Authors: Li Shuo , Li Wenyuan , Liu Bin , Krysan Kostyantyn , Dubinett Steven M.
Published: August 2024

Fragment-based marker discovery between LUAD and LUSC
Supplementary Table S3 from The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors
Authors: Heath Hannah , Yoo Jin Y. , Akter Sabrina , Jain Atharva , Sharma Vani , McGee Hannah , Soliman Aiman , Mahmoud Abeer M. , Matthews Alicia K. , Winn Robert A. , Madak-Erdogan Zeynep , Kim Sage J.
Published: August 2024

Pathway analysis results of cluster 6 genes from Figure 4A.
Supplementary Table S1 from The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors
Authors: Heath Hannah , Yoo Jin Y. , Akter Sabrina , Jain Atharva , Sharma Vani , McGee Hannah , Soliman Aiman , Mahmoud Abeer M. , Matthews Alicia K. , Winn Robert A. , Madak-Erdogan Zeynep , Kim Sage J.
Published: August 2024

Genes correlated with exposure to neighborhood violence.
Supplementary Figure S4 from The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors
Authors: Heath Hannah , Yoo Jin Y. , Akter Sabrina , Jain Atharva , Sharma Vani , McGee Hannah , Soliman Aiman , Mahmoud Abeer M. , Matthews Alicia K. , Winn Robert A. , Madak-Erdogan Zeynep , Kim Sage J.
Published: August 2024

Comparison of magnitude of GR binding sites in tumor vs. normal samples in high violence vs. low violence samples.
Supplementary Figure S1 from The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors
Authors: Heath Hannah , Yoo Jin Y. , Akter Sabrina , Jain Atharva , Sharma Vani , McGee Hannah , Soliman Aiman , Mahmoud Abeer M. , Matthews Alicia K. , Winn Robert A. , Madak-Erdogan Zeynep , Kim Sage J.
Published: August 2024

Heatmap and pathway analysis of genes correlated with neighborhood factors.
Figure S9 from Mathematical Modeling of Tumor Growth in Preclinical Mouse Models with Applications in Biomarker Discovery and Drug Mechanism Studies
Authors: Zhou Huajun , Mao Binchen , Guo Sheng
Published: August 2024

Figure S9
Figure S6 from Mathematical Modeling of Tumor Growth in Preclinical Mouse Models with Applications in Biomarker Discovery and Drug Mechanism Studies
Authors: Zhou Huajun , Mao Binchen , Guo Sheng
Published: August 2024

Figure S6
Figure S17 from Mathematical Modeling of Tumor Growth in Preclinical Mouse Models with Applications in Biomarker Discovery and Drug Mechanism Studies
Authors: Zhou Huajun , Mao Binchen , Guo Sheng
Published: August 2024

Figure S17
Figure S13 from Mathematical Modeling of Tumor Growth in Preclinical Mouse Models with Applications in Biomarker Discovery and Drug Mechanism Studies
Authors: Zhou Huajun , Mao Binchen , Guo Sheng
Published: August 2024

Figure S13
Figure S11 from Mathematical Modeling of Tumor Growth in Preclinical Mouse Models with Applications in Biomarker Discovery and Drug Mechanism Studies
Authors: Zhou Huajun , Mao Binchen , Guo Sheng
Published: August 2024

Figure S11
Figure 1 from Mathematical Modeling of Tumor Growth in Preclinical Mouse Models with Applications in Biomarker Discovery and Drug Mechanism Studies
Authors: Zhou Huajun , Mao Binchen , Guo Sheng
Published: August 2024

Parametric modeling of tumor growth data in mouse models. A, Proportion of each variable stabilization transformation V14, logV, and V-14 in the confidence sets of the K-L best model, for each parametric model. Log transformation accounts for the highest proportion (∼86%) in confidence sets for all six mathematical models. B–D, Proportion of each parametric model being the best model in terms of minimum AIC (B), AICc (C), and BIC (D), separated by mouse model type and treatment. E, Overall proportion of confidence sets that contain each of the six parametric models. F, Proportion of confidence sets that contain each of the six parametric models, separated by mouse model type and treatment. G, Proportion of confidence sets that contain either the exponential or exponential quadratic model. H, Proportion of experiments in which all experimental groups’ confidence sets contain each parametric model. I, For the 119 experiments in which not all experimental groups’ confidence sets contain the exponential quadratic model, the proportion of confidence sets containing each parametric model in each experiment. J, Proportion of experiments in which all experimental groups’ confidence sets contain each parametric model, separated by mouse model types.
Comparison of Esophageal Dysmotility and Reflux Burden in Patients with Different Metabolic Obesity Phenotypes Based on High-Resolution Impedance Manometry and 24-h Impedance-pH
Authors: He Tao , Zhang Mingjie , Tong Menghan , Duan Zhijun
Published: August 2024

Introduction: The relationship between the metabolically healthy obesity (MHO) phenotype and the occurrence of gastroesophageal reflux disease (GERD) and inefficient esophageal motility (IEM) is still unclear. Thus, we assessed the association between different metabolic obesity phenotypes and GERD and IEM using empirical data. Methods: We collected clinical and test data of 712 patients, including 24-h multichannel intraluminal impedance-pH (24-h MII-pH) monitoring, high-resolution manometry (HRM), and endoscopy. We divided 567 individuals into four categories according to their metabolic obesity phenotype: metabolically unhealthy non-obesity (MUNO), metabolically unhealthy obesity (MUO), metabolically healthy non-obesity (MHNO), and MHO. We compared differences in the 24-h MII-pH monitoring, HRM, and endoscopy findings among the four metabolic obesity phenotypes. Results: Patients with the MUNO, MHO, or MUO phenotype showed a greater risk of IEM and GERD (pathologic acid exposure time [AET] >6%) compared with patients with the MHNO phenotype. Regarding the HRM results, patients with the MHNO or MUNO phenotype had a lower integrated relaxation pressure, esophageal sphincter pressure, and esophagogastric junction contractile integral, and more ineffective swallows than patients with the MHO or MUO phenotype (p < 0.05). In terms of 24-h MII-pH, patients with the MHO or MUO phenotype had a higher total, upright, and supine AET; a higher total number of reflux episodes (TRs); and a lower mean nocturnal baseline impedance and post-reflux swallow-induced peristaltic wave index compared with those with the MHNO or MUNO phenotype (all p < 0.05). Considering the odds ratio of 19.086 (95% confidence interval 6.170–59.044) for pathologic AET and 3.659 (95% confidence interval 1.647–8.130) for IEM, patients with the MUO phenotype had the greatest risk after adjusting for all confounding variables. Conclusion: Obesity and metabolic disorders increase the risk of GERD and IEM. Obesity has a greater impact on esophageal dysmotility and pathologic acid exposure than metabolic diseases.
Geocronologia U-Pb (LA-ICPMS) de zircões dos distritos pegmatíticos de Santa Maria de Itabira e São José da Safira (Minas Gerais): populações contrastantes na região da Província Pegmatítica Oriental do Brasil?
Authors: Chaves Mario Luiz de Sá Carneiro , Pedrosa-Soares Antônio Carlos , Dussin Ivo Antônio , Menezes Filho Luiz Alberto Dias
Published: August 2024

Os distritos pegmatíticos de Santa Maria de Itabira (DPSM) e de São José da Safira (DPSJ) são classicamente integrantes da Província Pegmatítica Oriental do Brasil (PPOB), embora até então com carência de dados geocronológicos em termos regionais. Neste  estudo apresentam-se novas datações U-Pb (LA-ICPMS) de zircões extraídos de três pegmatitos desses distritos (Ponte da Raiz, Jaguaraçu e Ipê). Os zircões do Pegmatito Ponte da Raiz (DPSM), considerados magmáticos, fornecem uma robusta idade-concórdia em 1675 ± 5 Ma, indicando sua cristalização compatível com o magmatismo anorogênico da Suíte Granítica Borrachudos (~1,7 Ga). Os zircões do Pegmatito Jaguaraçu, do mesmo distrito, são metamícticos, fornecendo uma média de idades mais jovens de 508 ± 19 Ma que podem representar manifestações hidrotermais pós-colisionais no Orógeno Araçuaí. Os zircões do Pegmatito Ipê (DPSJ) apresentam idade-concórdia em 467 ± 5 Ma, interpretada como a da cristalização do corpo, valor similar à larga maioria das outras datações de pegmatitos do orógeno. Estes dados, aliados aos atributos mineralógicos dos pegmatitos/distritos estudados, evidenciam que o DPSM se caracteriza por pegmatitos berilíferos ricos em fluorita, amazonita e topázio, pertencendo à família NYF (nióbio-ítrio-flúor); possuem idade estateriana e representam magmas residuais de granitos da Suíte Borrachudos. Em contraste, o DPSJ constitui um distrito pegmatítico da família LCT (lítio-césio-tântalo), cujos pegmatitos são provenientes de magmas residuais de granitos tardi-orogênicos (pós-colisionais) do Orógeno Araçuaí. Em sentido mais amplo, a serem confirmados tais dados, o DPSM deve ser separado da PPOB, embora os depósitos quartzo-feldspáticos hidrotermais ricos em esmeralda/alexandrita que ocorrem em sua área geográfica estejam relacionados a um episódio hidrotermal tardio do Brasiliano.
Functional MRI signals exhibit stronger covariation with peripheral autonomic measures as vigilance decreases
Authors: Gold Benjamin P. , Goodale Sarah E. , Zhao Chong , Pourmotabbed Haatef , de Zwart Jacco A. , Özbay Pinar S. , Bolt Taylor S. , Duyn Jeff H. , Chen Jingyuan E. , Chang Catie
Published: August 2024

Vigilance naturally drifts over time, coinciding with marked changes in brain-wide functional magnetic resonance imaging (fMRI) signals. Though the precise origins of these hemodynamic changes are unclear, largely separate lines of research have linked different vigilance levels not only to changes in fMRI signal fluctuation amplitudes and functional connectivity, but also to significant variations in autonomic physiology. These findings raise the possibility that vigilance-related modulations in fMRI signals may arise in part from changes in autonomic physiology and their effects on cerebral hemodynamics. Here, using simultaneous recordings of fMRI, EEG-indexed vigilance, respiration, and pulse oximetry, we investigate how the relationship between autonomic and fMRI signals varies systematically as vigilance gradually drifts. Regression analyses indicated that the strength and extent of fMRI-autonomic covariation increased as vigilance diminished, during both resting state and an auditory vigilance task. Spatiotemporally, autonomic signals exhibited early positive correlations and delayed negative correlations with fMRI signals throughout much of the grey matter, accompanied by late positive correlations in the ventricles and periventricular white matter. Low-frequency EEG power fluctuations also demonstrated state-dependent associations with both fMRI and autonomic signals, with effects in fMRI that partially overlapped with those of peripheral autonomic variations. Functional connectivity between most brain networks strengthened as vigilance decreased, especially during resting-state scans, and removing autonomic variance from fMRI signals largely attenuated this effect. Together, these results demonstrate interactions between vigilance levels, autonomic physiology, and brain hemodynamics, showing that the physiological constituents of fMRI signals vary markedly over vigilance levels and brain regions. These findings contribute to knowledge of human brain physiology and toward the accurate parsing, analysis, and interpretation of fMRI data.
Cross-modal decoding of emotional expressions in fMRI—Cross-session and cross-sample replication
Authors: Wallenwein Lara A. , Schmidt Stephanie N.L. , Hass Joachim , Mier Daniela
Published: August 2024

The theory of embodied simulation suggests a common neuronal representation for action and perception in mirror neurons (MN) that allows an automatic understanding of another person’s mental state. Multivariate pattern analysis (MVPA) of functional magnetic resonance imaging (fMRI) data enables a joint investigation of the MN properties cross-modality and action specificity with high spatial sensitivity. In repeated-measures and independent samples, we measured BOLD-fMRI activation during a social-cognitive paradigm, which included the imitation, execution, and observation of a facial expression of fear or anger. Using support vector machines in a region of interest and a searchlight-based within-subject approach, we classified the emotional content first within modalities and subsequently across modalities. Of main interest were regions of the MN and the emotional face processing system. A two-step permutation scheme served to evaluate significance of classification accuracies. Additionally, we analyzed cross-session and cross-sample replicability. Classification of emotional content was significantly above chance within-modality in the execution and imitation condition with replication across sessions and across samples, but not in the observation condition. Cross-modal classification was possible when trained on the execution condition and tested on the imitation condition with cross-session replication. The searchlight analysis revealed additional areas exhibiting action specificity and cross-modality, mainly in the prefrontal cortex. We demonstrate replicability of brain regions with action specific and cross-modal representations of fear and anger for execution and imitation. Since we could not find a shared neural representation of emotions within the observation modality, our results only partially lend support to the embodied simulation theory. We conclude that activation in MN regions is less robust and less clearly distinguishable during observation than motor tasks.
Introduction: Falling Between Two Schools
Authors: Woerner-Powell Tom , Fiala Andrew
Published: August 2024

This introductory article situates research into Islamic notions of pacifism and nonviolence by considering interpretive challenges that include the history of Eurocentrism and the challenge of interdisciplinarity. It argues that both academic Philosophers and Religious Studies specialists confront a range of disciplinary challenges in interpreting and explaining Islamic nonviolence and pacifism. Moreover, the paper argues that the neglect of Islamic nonviolence in the modern Western academy is also the result of residual Eurocentrism, reflected in the fact that Christian nonviolence is better known and more widely studied in the Anglo-American world than Islamic nonviolence. This introductory article proposes that paying attention to disciplinary silos and Eurocentric biases can help explain the neglect of Islamic pacifism. This neglect is a contingent result of historical, cultural, and disciplinary factors; and there is no valid reason to exclude Islamic nonviolence from academic study.
A new Darwin wasp (Ichneumonidae: Novichneumoninae) from mid-Cretaceous Kachin amber
Authors: JOUAULT CORENTIN , HUANG DI-YING
Published: August 2024

Ichneumonid wasps, also known as Darwin wasps, are relatively rare in Cretaceous amber deposits, with only the highest diversity documented from mid-Cretaceous Kachin amber. In order to enhance our understanding of the past diversity of this group, we describe and illustrate a new species belonging to the genus Rasnichneumon Kopylov et al., 2021, named Rasnichneumon nevergo sp. nov. This newly discovered species is based on an exquisitely preserved specimen and can be readily distinguished from the congeners by its forewing, with 2-Rs slightly longer than 2+3-M. With the addition of this new species, the diversity of the genus Rasnichneumon now encompasses five species, and we anticipate the description of more species in the future.
A new genus of beaded lacewings (Neuroptera: Berothidae) from the mid-Cretaceous Myanmar amber
Authors: LI RUO-YU , LI HONG-YU , LIU XING-YUE
Published: August 2024

A new genus with a new species Anaberotha hui gen. et sp. nov. is described from mid-Cretaceous amber of northern Myanmar. Anaberotha gen. nov. has distinctive features of venation, which is closely related to other genera in the subfamily Cyrenoberothinae, such as Aggregataberotha Wang et al., 2023, Protoberotha Huang et al., 2019, Sibelliberotha Azar & Nel, 2013 and Speleoberotha Machado et al., 2022. Accordingly, Anaberotha gen. nov. may represent a unique evolutionary path of Cyrenoberothinae in mid-Cretaceous Myanmar.
New species and new records of Mesonemoura (Plecoptera: Nemouridae) from China
Authors: LI MENGYU , YANG DING , LI WEIHAI
Published: August 2024

A new species of the genus Mesonemoura, M. yadonga sp. nov. (Plecoptera: Nemouridae) is described from Xizang of southwestern China. The new species is compared to similar congeners. Two additional species are recorded for the first time from China. The hitherto unknown female of M. falcata (Kimmins, 1950) is described.
Purchase and Protect: Dual Effects of Tourist Souvenir Customization
Authors: Lv Xingyang , Yuan Zixin , Luo Jia , Fu Xiaoxiao , Shen Han , Ai Jin , Shen Yalan
Published: August 2024

As tourist souvenir consumption leans into co-creation, tourists transition from passive product consumers to active value co-creators. Drawing on psychological ownership theory, this study investigated how tourist customization simultaneously enhances the commercial and cultural attributes of tourist souvenirs through three studies. The findings revealed that tourists’ participation in souvenir customization not only stimulated their purchase behaviors toward souvenirs but also enhanced their willingness to protect the destination culture embedded within these tangible products. This dual effects was mediated by psychological ownership of the products and the culture they represent. Furthermore, the effects of tourist souvenir customization were moderated by the fit between the souvenir and the destination culture. This suggests that destination managers may organize souvenir co-creation activities and encourage tourists to incorporate local cultural and historical elements into souvenir customization.
Re-assessing the Dynamics of News Use and Trust: A Multi-Outlet Perspective
Authors: Aharoni Tali , Baden Christian , Overbeck Maximilian , Tenenboim-Weinblatt Keren
Published: August 2024

Communication research has long explored the association between media trust and news consumption. However, the strength and direction of this relationship have remained elusive. This study suggests a new approach for investigating these complex relations, differentiating between usage and trust associated with different sources over time. Focusing on the 2022 French election and drawing on data from a four-wave panel survey (N = 1,294), we utilized Random Intercept Cross-Lagged Panel Model (RI-CLPM) analysis to uncover two key over time effects: a selection effect, wherein trust reinforces usage; and a media effect, wherein usage influences trust. While a selection effect driven by news trust was observed in a right-wing political alternative channel, a media effect leading to news trust was linked with more traditional television channels. By identifying these effects and their associations with various types of outlets, this study advances the ongoing scholarly debate around the role of trust in news consumption.
A temporal dynamics framework and methodology for computationally intensive social media research
Authors: Kishore Shohil , Sundaram David , Myers Michael David
Published: August 2024

The growing availability of expansive social media trace data (SMTD) offers researchers promising opportunities to create rich depictions of societal and social phenomena. Despite this potential, research analysing such data often struggles to construct novel theoretical insight. This paper argues that holistically incorporating temporality enhances data collection and data analysis, subsequently facilitating process theory construction from SMTD. Recommendations to integrate temporality are outlined in the proposed Temporal Dynamics Framework and Methodology (TDFM). We apply the TDFM to investigate the temporal dynamics of mental health discourse on Twitter (now X) across different phases of the COVID-19 pandemic, theoretically framed in the context of innate psychological needs satisfaction. The findings reveal dynamic shifts in social media use, indicating that different phases of the pandemic triggered changes in the needs motivating, and being motivated by, social media use. This illustrative case reflectively evaluates the TDFM's usefulness in contextualising SMTD collection, analytical strategies, and process theory construction by incorporating a dynamic perspective on time.
Comparison of applied loads on horizontal axis wind turbine blades using an open-source software Qblade and CFD solver ANSYS-FLUENT
Authors: Huish Caden , Shakya Praveen , Seibi Abdennour C. , Arias Daniel , Shekaramiz Mohammad , Masoum Mohammad A. S.
Published: August 2024

As the wind energy sector rapidly advances, there is an increasing demand to improve energy efficiency and prolong the lifespan of wind turbines. Among the essential and costly components in the wind energy system, wind turbine blades (WTB) play a crucial role. Therefore, understanding the forces acting on WTBs holds significant importance. In this paper, WTB is modeled using NACA 4412 airfoil with 77.5 rotor radius in SolidWorks and Qblade. The geometry from SolidWorks is used to perform computational fluid dynamics (CFD) based on the Reynolds Averaged Navier-Stokes (RANS) approach in ANSYS-FLUENT software. Furthermore, the paper also includes the developed MATLAB code based on the Blade Element Momentum (BEM) method to validate the loads acting on the blade with Qblade and CFD results. Our thorough simulations and analyses reveal that the normal forces obtained from MATLAB and Qblade are in good agreement with CFD results while the tangential forces computed from MATLAB and Qblade defer from the CFD results.
Getting better at getting better: Advancing quality and safety in healthcare
Authors: Zelmer Jennifer
Published: August 2024

Scaling the innovative models of care, policies, practices, and technologies that deliver true value requires deliberate, focused effort. We need to simultaneously apply practical strategies that enable change agents to drive meaningful, sustainable impact to address particular challenges that a health system is facing, alongside implementing proven, evidence-informed approaches that broadly strengthen health system foundations. Both approaches matter; it’s not about choosing between them. Rather, we need to respond to the health system’s specific and immediate needs, while also growing culture, capacity, systems, and tools that enable transformation in quality and safety.
Rationale and design of ELIXIR, a randomized, controlled trial to evaluate efficacy and safety of XyloCore, a glucose-sparing solution for peritoneal dialysis
Authors: Bonomini Mario , Davies Simon , Kleophas Werner , Lambie Mark , Reboldi Gianpaolo , Liberato Lorenzo Di , Divino-Filho Josè Carolino , Heimburger Olof , Ortiz Alberto , Povlsen Johan , Iacobelli Massimo , Prosdocimi Tommaso , Arduini Arduino
Published: August 2024

Peritoneal dialysis adoption and technique survival is affected by limitations related to peritoneal membrane longevity and metabolic alterations. Indeed, almost all peritoneal dialysis fluids exploit glucose as an osmotic agent that rapidly diffuses across the peritoneal membrane, potentially resulting in metabolic abnormalities such as hyperglycemia, hyperinsulinemia, obesity, and hyperlipidemia. Moreover, glucose-degradation products generated during heat sterilization, other than glucose itself, induce significant morphological and functional changes in the peritoneum leading to ultrafiltration failure. The partial substitution of glucose with osmotic agents characterized by a better local and systemic biocompatibility has been suggested as a potential strategy to innovate peritoneal dialysis fluids. The approach aims to minimize glucose-associated toxicity, preserving the peritoneal membrane welfare and counteracting common comorbidities. In this work, we report the clinical trial design of ELIXIR, a phase III randomized, controlled, blinded outcome assessment study comparing Xylocore®, an innovative formulation based on Xylitol and l-carnitine, to standard glucose-based regimens, in end-stage kidney disease patients treated with continuous ambulatory peritoneal dialysis; 170 patients will be randomized (1:1) to receive XyloCore® or to continue their pre-randomization peritoneal dialysis (PD) therapy with glucose-only PD solutions, for 6 months. The primary study's objective is to demonstrate the noninferiority of XyloCore® in terms of Kt/V urea, for which a clinically acceptable noninferiority margin of −0.25 has been determined, assuming that all patients will be treated aiming to a minimum target of 1.7 and an optimal target of 2.0.
Psychedelics, Psychedelic-Assisted Therapy and Employees’ Wellbeing
Authors: Smith Charlie
Published: August 2024

There is a psychedelic renaissance with key drugs that alter perception and mood being given breakthrough therapy status as potential treatments for common mental health conditions. If approved, these drugs may be used alongside psychedelic-assisted therapy (PAT), a therapeutic process supporting learning from taking psychedelics. Nearly 100 companies, mainly across America, Canada, Europe, and Australia, are developing compounds such as psilocybin and lysergic acid diethylamide. This article considers the management research that could influence policymakers’ decisions and support employees undergoing PAT. Firstly, research on economic analyses that could inform policymakers’ approval decisions is outlined. Secondly, research exploring PAT's influence on employees’ wellbeing is noted. Thirdly, research on employees’ experiences of stigma around mental health, psychedelics and PAT is suggested. Developing these inquiries may influence employees’ PAT success and improve global mental health by encouraging successful work participation as a critical determinant of mental wellness.
Behavior monitoring of flax fiber reinforced composites by guided waves
Authors: Hana Driss , Moez Beyaoui , Zeineb Kesentini , Abderrahim El Mahi , Mourad Bentahar , Mohamed Haddar , Mandal Deba Datta
Published: August 2024

The mechanical behavior under static and fatigue loading induced by mechanical forces is examined in this article through the utilization of a non-destructive methodology. However, it is worth noting that the dynamics of elastic waves become notably more intricate when dealing with composite materials. In order to provide a comprehensive description of the green flax/epoxy system, a crucial component of this study involves the computation of guided wave dispersion curves within the test samples. By evaluating the longitudinal and shear modulus under varying stress conditions, the propagation of high-frequency ultrasonic waves, which serves as a dynamic mechanical deformation, can be leveraged to facilitate the comparison of both mechanical and ultrasonic data. The significant changes occurring during the aging process are closely associated with variations in velocity throughout the loading period. The wavelet transformation of all acquired ultrasonic echoes yields the experimental transfer function, thereby enhancing our understanding of the subject matter.
School-Based Victimization Prevention Education Programs for Children and Youth With Intellectual and Developmental Disabilities: A Scoping Review
Authors: Bright Melissa A. , Ortega Diana P. , Bodi Csenge B. , Walsh Kerryann
Published: August 2024

Youth with intellectual and developmental disabilities (IDD) are at significantly higher risk of experiencing multiple types of interpersonal victimization across their lifespan compared to their peers without IDD. Despite the extensive literature on efficacy of prevention education programs for children without IDD, very little is known about comparable programs for children with IDD. In this scoping review, we synthesized the literature on existing programs for children with IDD. We identified thirteen programs which we critically assessed against established best practice criteria for prevention and special education and evaluation. The current literature on prevention education programs for children with IDD exhibits significant limitations, such as weak research designs and poor measurement of outcomes.
Test methods for determination of shear properties of sandwich panels
Authors: Silwal Shekhar , Mela Kristo , Ma Zhongcheng
Published: August 2024

This paper presents analysis and comparison of test methods for determining transverse shear strength and shear modulus of steel-faced sandwich panels commonly used in construction. The test methods are taken from the governing European standard EN 14509:2013. Two-point loading and four-point loading test methods as well as a full-scale test method are examined. Based on extensive experimental work on sandwich panels with varying core thickness, comprising mineral wool (MW) and polyisocyanurate (PIR) and encompassing both roof and wall panels, this study provides details of the test setup for the four-point loading and vacuum box methods with which a pure shear failure is obtained. Such details are missing from EN 14509. This paper highlights that the two-point loading method fails to consistently produce shear failure, especially in thicker panels, indicating it does not accurately measure transverse shear strength. The results of the experiments conducted in this study indicate that the four-point loading and full-scale test methods provide consistent shear failure for thicker panels while yielding greater transverse shear strength than the two-point loading test in general.
Like Father like Daughter: Surgical Redo Thoracoabdominal Aneurysm Repairs in a Family With Loeys-Dietz Syndrome
Authors: Chen Joshua R. , Shah Vishal N. , Pritting Christopher , Nooromid Michael , Abai Babak , Plestis Konstadinos
Published: August 2024

Loeys Dietz Syndrome (LDS) is an autosomal dominant connective tissue disorder resulting from a mutation in the transforming growth factor beta receptor (TGFBR) family of genes. It is commonly associated with the development of aortic aneurysms and dissections. We report the successful open surgical management of thoracoabdominal aneurysms in a father and daughter with Loeys-Dietz Syndrome after failed endovascular repair. The daughter required stent graft explantation, while the stent graft remained in the father. These cases highlight the importance of early genetic testing of both patients and first-degree family members in those with a strong history of aortic disease, even when there is a lack of typical connective tissue disorder associated physical exam findings and open surgical index operations.
User practices in dealing with trouble in interactions with virtual assistants in German: Repeating, altering and insisting
Authors: Reineke Silke , Helmer Henrike
Published: August 2024

Moments of trouble and miscommunication occur regularly when users interact with virtual assistants like smart speakers. To add to the understanding of how users treat moments of trouble in everyday interactions with a virtual assistant (VA) in German, this paper reports on a conversation analytic study of practices that users deploy after a request to a VA has failed. The repair sequences that we analyse show users orienting to different trouble sources and employing a range of practices to resolve trouble, including repeating, altering their formulations and formulating related (new) requests. Most often, troubles are resolved after one instance of repair. Other repair sequences include several instances of repair and show more complex and diverse practices being employed. In some of these sequences, users ‘insist’ on their initial goal and/or strategy and do not always observably orient to the VA’s local reactions. In these cases, the interactional history with the VA and previously successful requests seem to play a role as well in the users’ local conduct.
Positioning to win: Key position-based performance indicators in elite soccer
Authors: Praça Gibson Moreira , Brandão Leandro Henrique Albuquerque , Silva Guilherme de Oliveira Santos , Oliveira Pedro Henrique de Almeida , Costa Varley Teoldo da , Pinheiro Guilherme Sousa
Published: August 2024

This study aimed to compare position-based variables between winning, losing, and drawing teams and to identify which among these variables would better predict the goal difference in the 2021–2022 German Bundesliga. The dataset comprised 275 official games, monitored through a semi-automatic camera system. For each game, players’ and ball’s positions were captured and exported in 10 Hz. Position-based variables comprised teams’ length, width, length per width ratio (LPWratio), stretching index, and near-the-ball space control in both offensive and defensive phases, as well as in the first and the second halves. Data were compared between the game outcomes using a Generalized Linear Model. Results indicated that winning teams in the Bundesliga tend to approach the first half of the game by expanding the field during the offensive phase (evidenced by a higher offensive width and stretching index), pressing high during the defensive phase (manifested through a greater defensive length), and exerting control over the space in the second half by concentrating players near the ball (indicated by higher near-the-ball space control). Differences between halves indicate that teams must be able to adapt their tactics during the game to succeed in the competition.
Centralised Development and Inactive Business Sector: The Case of Nakhon Si Thammarat City Municipality
Authors: Arporn Vithaya , Khompot Surat , Marddent Amporn
Published: August 2024

This article examines the relationship between the business sector and the policymaking of Nakhon Si Thammarat City Municipality in Southern Thailand. We find that business influence on local policy remains highly limited. We argue that this is primarily due to two factors: political and economic centralisation which limits the capacity of the municipal government, and the limited economic opportunities for medium and large businesses within the municipal borders. The result is that medium and large firms tend to focus their attention on and cultivate links with officials at the provincial and national level. At the same time, small businesses have expanded in the municipality. However, their inability to coordinate to make collective demands limits their influence on municipal policymaking. Instead, small entrepreneurs individually lobby the local government through the same channels as the general public, appealing for allocations from the government's limited community service budget.
Study on Antioxidant Activity and Immune-Enhanced Activity of Basil Crude Extract and its Solvent Fractions
Authors: Gu Jingjing , Ge Xiaolan , Zhang Mengjuan , Wang Lili , Ma Wei
Published: August 2024

Objective: Basil has various biological activities, and sufficient research on its extracts can help to clarify the main components that exert biological activity. Methods: Solvents with different polarities were used to extract the basil crude extract (CE), and the total polyphenol (TP) and total flavonoid (TF) contents of extracts were measured. The compounds of extracts were identified using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). Their antioxidant and immune-enhanced activities were evaluated. Results: The CE and its four solvent fractions were obtained including petroleum ether extract (PE), ethyl acetate extract (EE), n-butanol extract (BE), and water extract (WE). Among them, BE had the highest TP and TF contents, followed by EE, and all five extracts contained maltol and arbutin. The BE and EE have better 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities, while CE with less TP and TF contents showed better 2, 2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity than that of BE and EE. Besides, BE and EE also exert a better effect on relevant indicators of immunosuppressive mice than other extracts. Conclusion: The basil extracts (BE and EE), which have higher TP and TF contents, demonstrate better in vitro antioxidant activities and immune-enhancing effects on immunosuppressed mice. This provides a theoretical basis for the application of basil.