bluuebunny/crossref_metadata_2025 huggingface dataset:
STUDYING THE EFFECT OF “NORDIC WALKING” IN CONNECTION WITH THE DEVELOPMENT OF LANDSCAPING AND IMPROVEMENT OF SPECIAL ROUTES IN MOSCOW PARKS
Authors: Сорокопудов В.Н. , Березкина И.В. , Пирогова К.И. , Скакова А.Г. , Токарев Д.А. , Ханбабаева О.Е. , Ханбабаев Р.К.
Published: March 2022

Занятия скандинавской ходьбой не требуют организации специальных трасс на территории. Маршруты, возможно, организовать в высоко урбанизированном ландшафте городских парков и скверов, парковом ландшафте с обычным уровнем благоустройства, а также в природном ландшафте. Уровень благоустройства трасс варьирует от низкого, представленного только мягкими покрытиями, до высокого, с малыми архитектурными формами и площадками для отдыха, стендами с информацией, освещением в ночное время. Разрабатываются трассы различной сложности и благоустроенности. В озеленении трасс применяются растения, обладающие высокой декоративностью, высокой фитонцидной активностью, а также поглощающие пыль, смог и шум мегаполиса.

Nordic walking do not require the organization of special trails on the territory. Routes may be organized in a highly urbanized landscape of urban parks and squares, a park landscape with a usual level of improvement, and in a natural landscape. The level of improvement of trails varies from low, represented only by soft surfaces, to high, with small architectural forms and areas for recreation, stands with information, lighting at night. Routes of varying complexity and livability are being developed. In landscaping routes used plants with high decorative, high phytoncidal activity, as well as absorbing dust, smog and noise of the metropolis.
INFLUENCE OF GEOLOGICAL FACTORS ON FLOODING OF OIL WELLS (BY EXAMPLE OF THE VOROBIEVSKAYA AREA)
Authors: Гасумов Р.А. , Гасумов Э.Р. , Першин И.М. , Гасумов Р.Р. , Керимов А.Г.
Published: March 2022

В статье рассмотрен вопрос обводнения скважин и подъема водонефтяного контакта (ВНК) на примере месторождений Северного Кавказа. Приведен характер обводнения скважин нефтяных месторождений в зависимости от подъема ВНК и положения абсолютных отметок нижних перфорационных отверстий. Отмечены некоторые процессы обводнения нефтяных скважин на примере Воробьевской площади. Выявлены основные источники поступления вод при разработке нефтяных скважин.

The article considers the issue of wells fl ooding and rise of water-oil contact (WOC) by example of North Caucasus fi elds. Flooding character of oil fi elds wells depending on the WOC rise and the position of absolute levels for lower perforation holes is given. Some processes of oil well fl ooding are noted by example of the Vorobyevskaya area. The main sources of water infl ux during development of oil wells are revealed.
BIPHASE SYSTEM OF 2FM SIGNALS MATCHED WITH CONTINUOUS GAUSSIAN CHANNEL
Authors: Кузнецов В.С.
Published: March 2022

Система двухфазных сигналов 2ФМ является частным случаем разработанного ранее созвездия сигналов 2ФМАМ. Данное созвездие сигналов обладает достаточно высокой частотной эффективности (до 16,0 бит/(сГц)) и, начиная с 2ФМ4, обеспечивает надёжную работу на границе К.Э. Шеннона без применения помехоустойчивого кодирования.

System of biphase 2FM signals is a private chance of signal constellation 2FMAM, elaborated earlier on. This signal constellation possesses by suffi ciently high frequency effi ciency (up to 16,0 bit/(sHz)) and, starting from 2FM4, provides a reliable work on the C.E. Shannon bound without application of noise immunity encoding.
Многосеточные методы с косо-эрмитовыми сглаживателями для задач конвекции–диффузии с преобладающей конвекцией
Authors: Martynova T.S. , Muratova G.V. , Shabas I.N. , Bavin V.V.
Published: March 2022

The convection–diffusion equation with dominant convection is considered on a uniform grid of central difference scheme. The multigrid method is used for solving the strongly nonsymmetric systems of linear algebraic equations with positive definite coefficient matrices. Two-step skew-Hermitian iterative methods are utilized for the first time as a smoothing procedure. It is demonstrated that using the proper smoothers enables to improve the convergence of the multigrid method. The robustness of the smoothers with respect to variation of the Peclet number is shown by local Fourier analysis and numerical experiments.

Уравнение конвекции–диффузии с преобладающей конвекцией рассматривается на равномерной сетке центрально-разностной схемы. Многосеточный метод используется длярешения сильно несимметричных систем линейных алгебраических уравнений с положительно определенными матрицами коэффициентов. Двухшаговые косоэрмитовы итерационные методы впервые используются в качестве сглаживающей процедуры. Демонстрируется, что надлежащий выбор сглаживателей позволяет улучшить сходимость многосеточного метода. Локальный фурье-анализ и численные эксперименты приводят к выводу об устойчивости сглаживателей по отношению к изменению числа Пекле.
Potentialities and Limitations of Machine Learning to Solve Mixing Problems: A Case Study
Authors: Lynn Thomas , Ottino Julio , Lueptow Richard , Umbanhowar Paul
Published: March 2022

Cut-and-shuffle mixing is an instructive candidate system with which to assess the potential of machine learning (ML) as an approach to solve difficult mixing problems. We focus on a specific subset of cut-and-shuffle systems, the one-dimensional interval exchange transform. This class of mixing operations is well studied, and a simple mixing methodology, which we refer to as the longest segment (LS) method, works well under a broad range of situations. We use supervised learning to train a neural network (NN) to emulate the LS mixing algorithm for mixing a one-dimensional domain of two species. We find that a generic deep NN can emulate the LS method with good accuracy but cannot generalize to conditions significantly outside its training repertoire. The challenges in defining the mixing problem and generalizing a ML mixing approach are indicative of those expected for more complex systems where optimal or near optimal mixing methods remain unknown.
Mechanistic Insights of IscU Conformation Regulation for Fe–S Cluster Biogenesis Revealed by Variable-Temperature Electrospray Ionization Native Ion Mobility Mass Spectrometry
Authors: Lin Chen-Wei , Oney-Hawthorne Shelby D. , Kuo Syuan-Ting , Barondeau David P. , Russell David H.
Published: March 2022

Iron-sulfur (Fe-S) clusters are necessary for essential cellular processes such as oxidative respiration. In the householding ISC Fe-S biosynthetic pathway, the cysteine desulfurase enzyme IscS provides sulfur to the scaffold protein IscU, in which Fe–S clusters are assembled. Previous structural studies by crystallography and nuclear magnetic resonance (NMR) spectroscopy suggest that metamorphic IscU exists in at least a structured form and a disordered form, and switch conformation upon metal or IscS binding. Yet, there is debate on which form binds IscS and participates in Fe-S assembly. Also, previous NMR and circular dichroism spectroscopy results reveal the cold-denaturation of IscU and the effects of metal binding on cold-denaturation. The recent development of variable-temperature electrospray ionization (vT-ESI) native ion mobility mass spectrometry (nIM-MS) enables unprecedented informative studies that contain binding, structure, and temperature dependence in a single experiment. Here, vT-ESI nIM-MS is implemented to thoroughly investigate structure regulations of IscU and relations to Fe-S assembly. The results show clear cold/heat-denaturation of IscU as IscU shifts towards high charge states that have more extended conformation under extreme temperatures. Comparison of Zn-IscU and apo-IscU reveals that (i) Zn(II) binding attenuates the cold/heat-denaturation of IscU and promotes the refolding of IscU; (ii) Zn(II) binding prevents IscU shifting towards disordered high charge states, and only structured and intermediate forms bind Zn(II); and (iii) Zn(II) binding attenuates collisional induced unfolding (CIU) of the intermediate form. In the solution containing IscS, the temperature-dependent and chelator-dependent Zn(II) loss of IscU facilitates CIU of the intermediate form of IscU. Overall, these results suggest Zn(II) stabilizes and restricts the structural flexibility of IscU towards structure and intermediate forms. IscS binding loosens the intermediate form IscU active site local conformation to release Zn(II) for cluster assembly.
A fast polarizable water model for atomistic simulations.
Authors: Xiong Yeyue , Izadi Saeed , Onufriev Alexey
Published: March 2022

Simulating water accurately has been a major challenge in atomistic simulations for decades. Inclusion of electronic polarizability effects holds considerable promise, yet existing approaches suffer from significant computational overhead compared to the widely used non-polarizable water models. We have developed a globally optimal polarizable water model, OPC3-pol, that explicitly accounts for electronic polarizability with minimal impact on computational efficiency. OPC3-pol reproduces five key bulk water properties at room temperature with an average relative error of 0.6%. In atomistic simulations, OPC3-pol’s computational efficiency is in-between that of 3- and 4-point non-polarizable models; the model supports increased (4 fs) integration time step. OPC3-pol is tested in simulations of a globular protein and a B-DNA dodecamer with recent AMBER force-fields, demonstrating structure stability close to reference at multi-microsecond time-scale. The model can be trivially adopted by any package that supports standard non-polarizable force-fields and water models; its intended use is in long classical atomistic simulations where water polarization effects are expected to be important.
Operando acoustic analysis: a valuable method for investigating reaction mechanisms in mechanochemistry
Authors: Leroy César , Mittelette Sébastien , Félix Gautier , Fabregue Nicolas , Špačková Jessica , Gaveau Philippe , Métro Thomas-Xavier , Laurencin Danielle
Published: March 2022

We present a new operando approach for following reactions taking place in mechanochemistry, relying on the analysis of the evolution of the sound during milling. We show that differences in sound can be directly correlated to (physico)chemical changes in the reactor, making this technique attractive and complementary to others for monitoring mechanochemical reactions.
THE FEATURES AND THE MODEL OF ORGANIZATIONAL CHANGE FOR SMALL AND MEDIUM-SIZED BUSINESSES DURING PANDEMIC PERIOD
Authors: Божко Леся Михайловна
Published: March 2022

Цель статьи состоит в определении особенностей организационных изменений, позволяющих пережить предприятиям малого и среднего бизнеса период пандемии COVID-19, и разработке модели проведения организационных изменений для таких условий. Малые и средние предприятия испытывают характерные для своего формата проблемы, усугубляемые введением ограничительных мер. В статье сформулированы особенности организационных изменений, реализуемых малым и средним предпринимательством для целей сохранения бизнеса. Проводимые изменения направлены не только на выживание, но и на формирование стратегических результатов, способных укрепить положение компании в будущем. Научная новизна заключается в разработке модели проведения организационных изменений в период пандемии с учетом специфики малого и среднего бизнеса и нестабильности окружения. Полученные результаты исследования могут использоваться субъектами малого и среднего предпринимательства разных сфер путем постановки конкретных целей, задач, подбора приемлемых для конкретного бизнеса решений в части проведения изменений.

The purpose of the article is to identify the features of organizational changes that allow small and medium-sized businesses to survive the period of the COVID-19 pandemic, and to develop a model for conducting organizational changes for such conditions. Small and medium-sized enterprises are experiencing format-specific problems exacerbated by restrictive measures. The article describes the peculiarities of organizational changes implemented by small and medium-sized enterprises for the purpose of preserving business. The ongoing changes are aimed not only at survival, but also at shaping strategic results that can strengthen the company's position in the future. The scientific innovation consists in developing a model for carrying out organizational changes during the pandemic period, taking into account the specifics of small and medium-sized businesses and the instability of the environment. The obtained research results can be used by small and medium-sized enterprises of different spheres by setting specific goals, tasks, and selecting solutions acceptable for a particular business in terms of making changes.
IMPACT OF INDUSTRY 4.0 ON CHANGES IN THE CONTENT OF LABOR FUNCTIONS
Authors: Ширинкина Елена Викторовна
Published: March 2022

Актуальность исследования обусловлена тем, что текущий мировой рынок труда находится под воздействием IV промышленной революции (Индустрия 4.0). Цель исследования - оценить влияние циклических и внезапных трендов, воздействующих на рынок труда, и, как следствие, на формы организации труда и трудовые функции работников. В этой связи автором рассмотрены академические теории в контексте концептуализации влияния Индустрии 4.0 на рынок труда и трудовые функции, определены долгосрочные тренды трансформации рынка профессий. Научная новизна исследования заключается в обосновании концепции «Skills-biased technical change», смещенного в пользу высококвалифицированной рабочей силы, и теории вытеснения рутинного труда «Routine-biased technological change». Практическая значимость исследования заключается в обосновании выводов, учет которых позволит компаниям в условиях новых технологических вызовов соединить потребности бизнеса с фундаментальной подготовкой специалиста для его движения по новой карьерной траектории.

The relevance of the study is due to the fact that the current world labor market is under the influence of the IV industrial revolution (Industry 4.0). The purpose of the study is to assess the impact of cyclical and sudden trends affecting the labor market and, as a consequence, the forms of labor organization and labor functions of workers. In this regard, the author examines academic theories in the context of conceptualizing the impact of Industry 4.0 on the labor market and labor functions, identifies long-term trends in the transformation of the professions market. The scientific novelty of the research lies in the substantiation of the concept, biased in favor of a highly skilled labor force (skills-biased technical change, SBTC) and the theory of displacement of routine labor (routine-biased technological change, RBTC). The practical significance of the study lies in the fact that it will allow companies in the face of new technological challenges to combine business needs with the fundamental training of a specialist for his movement along a new career path.
HIGH-TECH COMPANY ROLE IN THE SYSTEM OF RUSSIAN SPATIAL DEVELOPMENT
Authors: Жуковский Андрей Дмитриевич
Published: March 2022

Целью статьи является: на основе анализа зарубежного и отечественного опыта выявить основные положения, подтверждающие значимость размещения и функционирования высокотехнологичных компаний в регионах Российской Федерации; показать, что факторы роста региональной инфраструктуры - научно-технический прогресс и цифровизация, развитие человеческого капитала, инвестиции в развитие региона, концентрация высокотехнологичных компаний в регионе - способствуют эффективному развитию территорий, ускорению социально-экономического развития страны, а также повышению конкурентоспособности экономики в целом. Обоснован тезис, что размещение высокотехнологичных компаний в регионах будет эффективным инструментом повышения конкурентоспособности и инвестиционной привлекательности регионов для инвесторов при быстро меняющейся конъюнктуре мирового рынка в условиях перехода на возобновляемые источники энергии и снижающейся доли экспорта и потребления углеводородов в мире. С этой целью проанализирован национальный и зарубежный опыт процессов регулирования пространственного развития на макро (национальный и наднациональный), мезо (региональный, субнациональный) и микро (местный) уровнях для оценки различных моделей пространственного развития и факторов размещения высокотехнологичных компаний.

The purpose of the article is to identify the main provisions confirming the significance of the placement and functioning of high-tech companies in the regions of the Russian Federation; show that the growth factors of the regional infrastructure such as scientific and technological progress and digitalization, the development of human capital, investments in the development of the region, the concentration of high-tech companies in the region can contribute to the effective development of the territories, the acceleration of the socio-economic development of the country, as well as the increase of the competitiveness of the economy as a whole. The article justifies that placing high-tech companies in the regions is an effective tool for increasing the competitiveness and investment attractiveness of the regions for investors in the rapidly changing world market conditions in the context of the transition to renewable energy sources and the declining share of hydrocarbon exports and consumption in the world. The author analyses the national and foreign experience of spatial development regulation processes at macro (national and supranational), meso (regional, subnational) and micro (local) levels to assess various spatial development models and placement factors of high-tech companies.
Septins tune lipid kinase activity and PI(4,5)P2 turnover during G-protein–coupled PLC signalling in vivo
Authors: Kumari Aastha , Ghosh Avishek , Kolay Sourav , Raghu Padinjat
Published: March 2022

Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] hydrolysis by phospholipase C (PLC) is a conserved mechanism of signalling. Given the low abundance of PI(4,5)P2, its hydrolysis needs to be coupled to resynthesis to ensure continued PLC activity; however, the mechanism by which depletion is coupled to resynthesis remains unknown. PI(4,5)P2 synthesis is catalyzed by the phosphorylation of phosphatidylinositol 4 phosphate (PI4P) by phosphatidylinositol 4 phosphate 5 kinase (PIP5K). In Drosophila photoreceptors, photon absorption is transduced into PLC activity and during this process, PI(4,5)P2 is resynthesized by a PIP5K. However, the mechanism by which PIP5K activity is coupled to PI(4,5)P2 hydrolysis is unknown. In this study, we identify a unique isoform dPIP5KL, that is both necessary and sufficient to mediate PI(4,5)P2 synthesis during phototransduction. Depletion of PNUT, a non-redundant subunit of the septin family, enhances dPIP5KL activity in vitro and PI(4,5)P2 resynthesis in vivo; co-depletion of dPIP5KL reverses the enhanced rate of PI(4,5)P2 resynthesis in vivo. Thus, our work defines a septin-mediated mechanism through which PIP5K activity is coupled to PLC-mediated PI(4,5)P2 hydrolysis.
FOOD SECURITY OF THE RUSSIAN FEDERATION UNDER THE INFLUENCE OF FOREIGN POLICY FACTORS AND CURRENT RESTRICTIVE MEASURES IN THE CONTEXT OF A PANDEMIC
Authors:   State University of Management, Bogdanova Marina V. , Belikova Mariya P. ,   Russian State University of Justice
Published: March 2022

Object: to study the current state of food security in the Russian Federation. Methods: Observation method, comparative analysis method, formal legal method. Findings: Indicators of food security play a significant role for the economy of a country as a whole. To a greater extent, the difference between developed and developing countries lies in the absence of serious jumps in various indicators assessing the level of economic development and well-being of the country's population. Since 2014, the decline in economic indicators has been clearly visible, which, on the one hand, is an objective consequence of the sanctions that were applied by a number of developed countries against Russia in order to achieve political compromises, on the other hand, the negative global situation on the spread of a dangerous virus, which provoked the adoption of various measures, starting with supply restrictions and ending with the complete closure of a number of enterprises, which at the moment led to a real and unpleasant fact of a decline in the standard of living for Russian citizens. The world as a whole and Russia in particular, of course, were able to resist and cope with the conditions of the pandemic, which affected all spheres of society, but further recovery and development requires a review of the existing economic policy of food security. Conclusion: The Russian Federation needs to prevent fluctuations in the level of food security by building more constructive relations with Western countries already in the new realities of 2021. In addition, it is necessary to establish closer ties with Japan, South Korea and other developed countries that have not imposed sanctions, but are aimed at mutually beneficial cooperation and support. It is important to note that the level of food security largely depends on the predictability of the international situation, as well as on the specific relations between countries.
THE EFFECTIVENESS OF THE IMPLEMENTATION OF NATIONAL PROJECTS IN THE RUSSIAN FAR EAST IN THE CONTEXT OF HUMAN CAPITAL
Authors:   Institute for Demographic Research FCTAS RAS, Zorin Dmitry P.
Published: March 2022

This article is devoted to the study of existing programs aimed at demographic stabilization of the Far Eastern regions of Russia, as well as the analysis of human capital indicators. To date, there are a number of pressing demographic problems characteristic of the region, such as depopulation and labor shortage. The paper describes the impact of natural attrition, migration outflow and decrease of the population permanently residing in the region on the growth of human capital. The basis of the work consists of data from the Federal State Statistics Service, the Federal Migration Service, statistical information on the migration situation provided by the Ministry of Internal Affairs of Russia, as well as materials presented in domestic and foreign scientific publications. A significant factor in the sustainable economic growth of the Far Eastern regions of Russia is the growth of human capital. Its differentiation at the level of individual subjects of the Federation is determined by the differences in the complex of existing socio-economic conditions, as well as the demographic structure of the population. The paper analyzes the impact of human capital on economic growth. The features of interregional differentiation of human capital in Russia and the Far East are shown. Some trends of the socio-economic situation in the regional context of the Russian Far East are described, as well as key tools for the formation of human capital in the region are formulated.
CURRENT PROBLEMS AND CURRENT TRENDS IN THE DEVELOPMENT OF INTERNATIONAL TOURISM, TAKING INTO ACCOUNT THE MULTIFACTORIAL IMPACT OF THE COVID-19 PANDEMIC
Authors:   Financial University under the Government of the Russian Federation, Shestemirov Alexei A. ,   Moscow City University of Management of the Government of Moscow named after Yu.M. Luzhkov, Shinkareva Olga V. ,   Moscow City University,   Moscow City University of Management of the Government of Moscow named after Yu.M. Luzhkov, Kondratenko Alina A. ,   Moscow City University of Management of the Government of Moscow named after Yu.M. Luzhkov
Published: March 2022

This article is devoted to the study of the state of international tourism in the current epidemiological situation. The study determines the importance of development of the tourism industry in the world, analyzes the economic impact of the COVID-19 pandemic on the international tourism industry, and examines the current trends in the sector. It was noted that the regions most vulnerable to changes in the tourism market are Asia and the Pacific (Macau (China), Fiji) and Europe (Spain, Croatia, Montenegro). It was emphasized that the measures taken by many States to support tourism during the pandemic period, such as the introduction of job protection programs, the development of training and retraining schemes aimed at developing new skills important in post-pandemic reality; payments to small and medium-sized enterprises in the tourism industry, their exemption from taxes and fees, etc. It was concluded that the main trends in the tourist market at present are digitalization, individualization of travel, the predominance of local tourism. Priority tasks formulated by the World Tourism Organization are revealed, which should contribute to the restoration of the industry.
RISKS IN THE SYSTEM OF PUBLIC PROCUREMENT MANAGEMENT: IDENTIFICATION AND ASSESSMENT
Authors:   MGIMO University, Stroganova Yevgenia V.
Published: March 2022

This article presents an original methodology for assessing the cumulative risk of procurement in the state contract system. A classification of procurement risks is proposed, including time risk, corruption risk, financial risk, organizational and legal risks and technical risks specific to each procurement entity (customer, contractor and consumer) at each stage of the procurement process (procurement planning, procurement implementation, monitoring, audit and control of procurement), including the allocation of procurement risks before the conclusion of the contract and during the execution of the contract. The risk assessment methodology includes a quantitative assessment of the private risks of all participants at different stages of procurement and the total risk of procurement using matrix and point approaches. The verification of the methodology showed the ability to determine the comparative overall risk in the field of procurement and bottlenecks both in the activities of a particular customer and contractor, and in the industry and the procurement system as a whole. The use of classification and risk assessment methodology in the field of public procurement makes it possible to develop a risk-based approach to management in the russian contract system, which is conceptually based on the concentration of limited state resources in areas of maximum risk and at the same time reducing the administrative burden in areas of reduced risk.
Spectral Characteristic of Phosgene in External Electric Field
Authors: An Huan , Xiang Mei , Abulimiti Bumaliya , Zhen Jingyan
Published: March 2022

Phosgene is highly toxic, and it plays a role in the depletion of the ozone layer. The ground state geometric structure and spectral characteristic of phosgene in various external electric fields were calculated via the density-functional theory (DFT) and time-dependent density-functional theory (TDDFT) with the B3LYP/6-31+G(d) basis set. With external electric field, the structure of phosgene changed significantly. With increasing electric field, the bond lengths of 1C-3Cl and 1C-4Cl increased; the total energy and energy gap initially increased and then decreased, whereas the dipole moment initially decreased and then increased. Most of the IR vibrational frequencies were redshifted. The wavelength of the singlet excited state increased, reflecting a red shift, and the oscillator strengths of most transitions belonged to forbidden transitions. These results are of great significance for studying the dissociation of phosgene in external electric field.
生态环境保护综合行政执法的现实困境与完善路径
Authors: 田 野
Published: March 2022

针对中国生态环境保护执法的实际情况展开实地调研并且开展问卷调查，最终集中归纳总结问题。发现在生态环境保护综合行政执法的过程中仍然存在很多问题，如机制不健全、执法不规范等。
乡镇加油站建设规划选址思考
Authors: 声富 邹
Published: March 2022

加油站是成品油销售服务的终端，随着消费水平的日益提高，车辆的不断增多，成品油需求日益增长，提前规划布局好一个功能完善、选址合理、有序竞争的加油站在当前显得尤为重要。
新环保法下环评制度与环评技术的新发展研究
Authors: 广 李
Published: March 2022

中国正处于经济社会发展以及社会经济体制转型的关键时期，在经济的快速增长中我们也面临着资源约束和环境污染加剧的时代问题。对此，做好环境保护工作是当前中国生态文明建设以及美丽中国建设的重要保障措施。新环保法的出台进一步中国的环评工作指明了方向，是推动中国环保工作开展的重要法律法规保障。就当前而言，中国的环评工作在开展的过程中依然面临的诸多的问题，论文针对新环保法的视域探讨环评制度和环评技术深入落实和发展的对策。
谈环境监测在环境保护中的作用与发展
Authors: 志刚 黄
Published: March 2022

环境污染不但威胁着人类健康，而且还会阻碍国家经济发展。环境监测技术可以及时、准确地反映当前所监测区域内的环境质量，并利用大数据分析技术来研究当前环境问题的变化趋势，可以为环境保护工作提出切实可行的依据，是环境整体系统工作的重要基础。
市政道路工程沥青混合料路面的质量通病及防治措施探讨
Authors: 晨宁 王 , 永帅 张 , 同生 刘
Published: March 2022

沥青混合料路面是道路建设中常见的路面形式，沥青混合料路面具有路面平整度高、施工所需时间短、道路养护相对简单方便等特点，而且沥青混合料路面耐久性能与抗滑性能也相对较高。当前阶段，沥青混合料已经成为中国市政道路施工中广泛应用的材料，但是由于受到外部环境，工程设计等多方面因素的影响，沥青混合料路面出现病害的风险也相对较高。论文主要对沥青路面常见质量通病及原因进行分析，并就沥青混合料路面质量通病的防治措施与处理方法谈一些体会。
中国海口市某公共文化设施建筑空调冷源系统设计
Authors: 文林 罗
Published: March 2022

通过对中国海口某公共文化设施项目空调冷源的比选，获得了适宜的冰蓄冷空调冷源配置方案[1]。对项目空调冷源进行了初投资及运行费用的综合经济比较分析，认为后者经济效益优于前者，可供其他类似项目设计参考。
城市地下综合管廊监控系统研究及应用
Authors: 燕 秦
Published: March 2022

地下综合管廊是建设在城市地下，用于集中敷设电力、通信、天然气、给水等市政管线的公共隧道。它可有效杜绝“马路拉链”现象，让技术人员无需反复开挖路面，在管廊中就可对各类管线进行抢修、维护，大大缩减管线抢修时间。为对综合管廊的运行状态进行实时监测，确保稳定、长期的运作，从而配置监控系统。基于物联网一体化的统一管理平台，从数据采集、通信网络、智能联动和大数据分析方面解决管廊监控系统中存在着内部干扰性强、使用单位多及协调复杂的问题，实现对综合管廊内部设备的远程管理及智能管控。论文以当前所运行的地下综合管廊实例，对管廊监控系统的功能、构建进行分析，对一些可以提出优化的部分给出建议。
城镇化进程中农村土地征收的现实困境与路径选择思考
Authors: 琪 章
Published: March 2022

城镇化进程，指的是农村人口逐步朝城镇转移，第二、三产业逐步朝城镇聚集的发展过程，也是城镇数量增多，城镇规模扩大的一种历史发展过程。值得注意的是，在城镇化进程中，农村土地征收工作持续推进，但此项工作存在一些现实困境问题。因此，论文以城镇化进程中农村土地征收的现实困境问题为切入点，进一步分析城镇化进程中农村土地征收的路径选择策略，希望以此全面提高农村土地征收工作的质量水平。
浅谈城区复杂环境下给排水管道施工工艺
Authors: 万齐 姜
Published: March 2022

论文以中国四川省成都市新都区主城区给排水管道施工为实例，对城区复杂环境下给排水管道施工遇到的主要问题进行分析和总结，并提出了对传统板式支护工艺进行改进，将其组成快速支撑体系，按照“短开挖，快支护”原则进行施工，形成一套适用于城区外部复杂环境下的技术参数。经实践证明，该项新工艺具有易于控制质量、保证安全、加快进度、节约施工成本等特点，取得良好效果。
城市园林绿化工程施工及养护管理分析
Authors: 红颖 冯
Published: March 2022

论文以园林绿化工程施工及养护管理为研究对象，首先对加强园林绿化工程施工管理的必要性进行了探讨分析，随后从施工管理角度入手，提出了一些园林绿化工程施工管理措施，最后从养护管理入手，提出了一些针对性养护管理措施，希望能够为相关研究提供一定的参考。
城市人行道景观设计研究
Authors: 雪 高
Published: March 2022

在城市建设过程中，需要结合特色的景观风格进行设计方案的选择，进而突出城市特色达到更好的城市建设效果。论文则从城市人行道景观设计所遵循的原则着手，对其基本情况进行分析，了解景观设计的内容和方法，主要包括人行道线条的设计、人行道交通功能的设计以及人行道节点的设计等几个方面的内容，仅供参考。
北方城市园林绿化养护方法及管理措施
Authors: 伟 郑
Published: March 2022

城市园林绿化养护是提高城市绿化水平的关键。通过当前社会发展条件下城市绿化养护管理的重要性，体现现阶段城市园林绿化养护管理过程中存在的问题，分析城市园林绿化养护工作的特点，并从园林绿化养护方法及管理措施两个方面探究并实施。
A LITERATURA DE CORDEL COMO FERRAMENTA PARA A AQUISIÇÃO DO LETRAMENTO LITERÁRIO EM TURMA DE 9º ANO DO ENSINO FUNDAMENTAL
Authors: Oliveira Sebastião José Leones de , Timbane Alexandre António
Published: March 2022

A literatura é uma das expressões artísticas mais significativas na história das civilizações, porque o homem constrói o mundo real e imaginário. Ao analisarmos o ensino da literatura, nota-se o quanto o trabalho com essa arte, em sala de aula tem demonstrado um tanto quanto ineficaz, haja vista falta de cultura literária por parte dos estudantes. Nesse contexto, é visto na Literatura de Cordel uma fonte alternativa de trabalho com a prática literária, pois esta carrega importantes marcas e traços de nossa história e cultura popular. O capítulo propõe uma intervenção pedagógica em turmas de 9º ano do Ensino Fundamental, a partir da utilização da Literatura de Cordel, fundamentada pela metodologia da Sequência Básica sugerida por Cosson (2021). Por meio de ações organizadas e sistematizadas somos capazes de proporcionar o acesso a outras leituras contribuindo para a formação do futuro leitor.Palavras chaves: Leitura. Literatura de Cordel. Letramento Literário.
PESQUISA EM EDUCAÇÃO: QUESTÕES POLÍTICO-INSTITUCIONAIS E DE FORMAÇÃO DO PESQUISADOR
Authors: Borba Siomara Moreira Vieira , Gregório Tânia Cristina da Conceição , Souza Alexandre Augusto e
Published: March 2022

Neste capítulo, pretende-se abordar a pesquisa em educação, considerando o processo político-institucional, com a criação dos programas de pós-graduação, e a formação do pesquisador. Para tanto, apresenta-se esta temática a partir de uma pesquisa bibliográfica, com o objetivo de trazer ao debate questões concernentes ao campo acadêmico institucionalizado como locus principal da formação do pesquisador e da consolidação da produção de conhecimento científico. O referencial teórico que subsidia a apresentação da temática centra em Florestan Fernandes e Pierre Bourdieu.
1,2-Bis[bis(pyridin-2-yl-methyl)phosphino]ethane and its PdCl2-based complex: synthesis and crystal structure
Authors: Baranov A.Yu. , Sukhikh T.S. , Artem’ev A.V.
Published: March 2022

1,2-Bis[bis(pyridin-2-ylmethyl)phosphino]ethane, R2PCH2CH2PR2 (R = 2-PyCH2), has been synthesized in 92% yield via the reaction of Cl2PCH2CH2PCl2 with 2-[(trimethylsilyl)methyl]pyridine. Treatment of this phosphine with Pd(COD)Cl2 affords chelating complex of [PdLCl2] type, wherein the Pd(II) ion displays a square-planar [Pd@Cl2P2] geometry.
Oligocene Climate Changes of Java
Authors: Lelono Eko Budi , Morley Robert J
Published: March 2022

The study of palynology performed on the Oligocene marine sediment of the East Java Sea provides excellent recovery which allows the construction of palynological succession which applies regionally (Lelono et. al., 2011). In fact, this succession is characterized by assemblages that suggest climatic changes. These assemblages are divided into two major groups including mangrove and hinterland. The hinterland pollen group shows the most interesting succession, with elements on the one hand suggesting everwet climates (Dacrydium and Casuarina), and seasonal elements on the other (Gramineae, Schoutenia and Malvacipollis diversus). Mangrove pollen however suggests strong environmental control since mangrove pollen shows different abundance variations in the two wells. The age of the studied succession is independently defined using combined marine micro-fossils of foraminifer and nannoplankton which indicate Early to Late Oligocene. Although for most of the Oligocene in Southeast Asia, seasonal climate assemblages are the rule, this study interpretes the appearence of everwet climates. The Early Oligocene is characterized by common rain forest elements, suggesting an everwet rain forest climate at that time. The early part of the Late Oligocene, however, contains much reduced rain forest elements, and the presence of regular Gramineae pollen, suggesting a more seasonal climate, whereas for the latest Late Oligocene, rain forest (and peat swamp) elements return in abundance, suggesting a very wet rain forest climate. In fact, Java region experienced the wettest climate during Oligocene which probably reflected a wet climate fringe to the eastern margin of Sundaland prior to the collision of the Australian and Asian plates at the Oligo-Miocene boundary.
Electric properties of black arsenic
Authors: Fedotova J. A.
Published: March 2022

R(T, B) of the natural black arsenic (b-As) polycrystal was studied. It was shown that the polycrystalline b-As sample contains the b-As phase and also the traces of its oxide, as well as grey arsenic and arsenolite (As2O3). The behavior of the relative magnetoresistance of the b-As crystal was described by the relation MR(B) = bBn + cBm, where the coefficients b and c and the exponents n and m were also affected by the mechanisms of magnetoresistance formation and temperature. At the temperatures below 10 K, MR(B) shows the presence of a competition between negative (with b < 0 and n ≈ 0.5) and positive (with c > 0 and m ≈ 1) contributions. Above 10 K, only the PMR effect was presented. For the PMR effect, at 10 < T < 100 K it is observed that the values of b > 0, n ≈ 1 and c → 0. Above 100 K, it is observed that the values of b, c > 0 and n ≈ 1 and 1.30 < m < 1.47. The observed behavior of the R(T, B) dependences is associated with strong inhomogeneity and/or disorder of the investigated black arsenic crystal.
Rheological properties and in vitro hydrolytic stability of the carboxymethylcellulose–dioxidine composition
Authors: Yurkshtovich T. L. , Yurkshtovich N. K. , Golub N. V. , Kosterova R. I. , Pristromova Y. I. , Solomevich S. O. , Bychkovsky P. M.
Published: March 2022

The composition of carboxymethylcellulose–dioxydine was obtained and its structural, morphological and rheological characteristics in the processes of heat treatment and chemical hydrolysis were studied. Using IR spectroscopy, scanning electron microscopy, and viscometry, it has been established that the introduction of dioxidine into a solution of carboxymethylcellulose sodium salt with different molecular weights leads to partial disordering of hydrogen bonds between macromolecules, promotes thermal destruction of the polysaccharide and a decrease in the dynamic viscosity of solutions. Experimental kinetic curves of carboxymethylcellulose hydrolysis in the presence and absence of dioxidine were obtained, and it was shown that they could be described using a first-order equation. The hydrolysis rate coefficients were calculated, and it was shown that, as a result of heat treatment, as well as in the presence of an active substance, the rate of carboxymethylcellulose hydrolysis increased. The change in the rheological properties of carboxymethylcellulose sodium salt solutions with different degrees of polymerization in the presence of an antimicrobial substance should be taken into account when choosing the composition of viscous prolonged forms of biologically active substances.
Effect of autological red bone marrow aspirates on the microcirculation in the lower extremities of patients with diabetic angiopathy
Authors: Kamiandrouskaya A. A. , Fedzyanin S. D. , Kovalenko A. A. , Ratomski Yu. I.
Published: March 2022

The lesion of the lower extremities vessels is one of the most dangerous complications of diabetes mellitus. The prognosis is bad in case of the development of critical ischemia.

The aim of the study is to assess the effect of autological red bone marrow aspirates on the microcirculation in the soft tissues of the lower extremities of patients with diabetic angiopathy.

The study included 36 patients with diabetic angiopathy of the lower limbs. The main group of 20 people consisted of the patients, whose treatment was added by revascularizing automyelotransplantation. The comparison group (16 people) included the patients who received standard complex conservative treatment.

All patients underwent pulse oximetry on the 1st toe before the treatment start and within the control times. The painless walking distance was also assessed and the chronic arterial insufficiency stage was determined.

In the main group, 18 patients retained their lower limbs, in the comparison group - 10 patients (pCox-Mantel = 0.015).

There was an increase in the painless walking distance in 15 out of 18 patients in 3-6 months after treatment in the main group. There was no improvement in the comparison group. Chronic wounds healed in 4 out of 7 patients.

The median SpO2 in the main group was 96 [92; 97] %, in the comparison group - 90 [88; 92] % (pMann_Whitney = 0.0035).

The inclusion of revascularizing automyelotransplantation in the complex treatment of patients with diabetic angiopathy of the lower extremities contributes to the lower extremity preservation, as well as the relief of critical ischemia signs and the healing of chronic wounds.
The efficiency of remote ischemic postconditioning of the myocardium in rats with induced metabolic syndrome depends on the leptin level
Authors: Naryzhnaya N. V. , Logvinov S. V. , Kurbatov B. K. , Mukhomedzyanov A. V. , Sirotina M. A. , Chepelev S. N. , Vismont F. I. , Maslov L. N.
Published: March 2022

Remote postconditioning (RPost) has a great therapeutic potential for protecting the myocardium during ischemiareperfusion in clinical practice. At the same time, an important problem limiting the use of conditioning effects in the clinic is the presence of metabolic disorders in the patient. The aim of this work was to assess the effect of induced metabolic syndrome (iMetS) on the efficacy of the infarct-limiting effect of remote ischemic postconditioning (RPost) in rats and to study the mechanisms of this effect.

The study was carried out on Wistar rats. MetS was induced by high-carbohydrate high-fat diet. Criteria of metabolic syndrome were an increase in the weight of animals, abdominal fat volume, the development of arterial hypertension, hypercholesterolemia, an increase in triglycerides in serum, hyperleptinemia, hyperglycemia, the development of a state of insulin resistance by a significant increase in the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) index and glucose tolerance. All animals were subjected to 45 min coronary occlusion and 120 min reperfusion.

RPost led to a twofold reduction of infarct size in rats with intact metabolism (р< 0.0001), while in rats with iMetS a decrease in infarct size during RPost was 25 % (p= 0.00003), which was significantly lower than in animals without iMetC (р< 0.0001). A direct correlation was found between of infarct size during RPost and the serum leptin level of rats with iMetC.

The presented data suggested that a decrease in the efficiency of remote postconditioning in rats with diet-induced metabolic syndrome depends on leptin content in blood.
Rationale importance of integrated determination of the level of CYFRA 21-1 and the receptors CXCR1, CXCR2, CD44v6 in the blood of patients with early-stage non-small cell lung cancer for predicting the tumor progression risk
Authors: Tahanovich A. D. , Kauhanka N. N. , Prohorova V. I. , Murashko D. I. , Kolb A. V. , Gotko O. V. , Matusevich V. A.
Published: March 2022

Only 60-70 % patients with stage I and 35-40 % with stage II of non-small cell lung cancer (NSCLC) overcome the 5-year survival. The reason for such a high mortality rate is almost always a disease recurrence due to the presence of hidden metastases. This indicates a different course of the disease within one stage. There is a need to develop indicators that would allow predicting the tumor progression in patients at the early tumor development stages in order to correctly build the strategy and tactics of their treatment.

The objective of the study is to find and substantiate the possibility of using the laboratory parameters characterizing the level of blood proteins involved in carcinogenesis when predicting the NSCLC progression in patients with early disease stages.

In 1250 patients (839 men and 411 women) who were first diagnosed with NSCLC in the early stages (I and II), the duration of the recurrence-free period after treatment was analyzed according to the one-year observation results. In 103 patients (56 ± 22.5 years), the level of CYFRA 21-1, SCC, TPA, M2 of pyruvate kinase, chemokines CXCL5, CXCL8 and the concentration of HIF1a and hyaluronic acid in blood serum were determined by the enzyme immunoassay and that of the receptors CXCR1, CXCR2, CD44v6 in blood granulocytes, lymphocytes and monocytes - by flow cytometry. 62 persons had stage I (G1 - 20, G2 - 23, G3 - 19) and 41 - stage II (G1 - 14, G2 - 15 and G3 - 12).

Based on the results of the one-year observation and the graphic analysis of Kaplan-Meier, the groups of low (stage I, G1-2 + stage II, G1) and high (stage I, G3 + stage II, G2-3) risk of tumor progression were identified. In high-risk patients, compared with low-risk patients, the level of CYFRA 21-1, the fluorescence intensity of the receptor CXCR1 in granulocytes, the relative content of the receptor CXCR2 in lymphocytes and the receptor CD44v6 in monocytes were higher (p< 0.05). With their participation, according to the results of logistic regression analysis, an equation was constructed, the calculation of which allows predicting the risk of tumor recurrence. The threshold for the equation is 0.467. The sensitivity of the forecasting model is 84.8 %, the specificity is 84.2 %, the predictive values of positive and negative results are 81.2 and 87.3 % respectively.

The study results showed that a set of laboratory parameters, including blood CYFRA 21-1 level in combination with CXCR1, CXCR2, CD44v6 can be used in patients with early stages of NSCLC to assess the risk of tumor progression.
Primary School Teachers’ Orientations on Integratıve STEM Practices: İzmir Bornova Sample
Authors: ATALAY Sevim , HAMURCU Hülya
Published: March 2022

In order to adapt to the changing and developing age, innovations continue in the field of education. STEM education, in which many disciplines are used together, is one of them. The aim of this study is to determine the orientation of primary school teachers towards STEM applications. STEM; It is a combination of the initials of the words science, technology, engineering and mathematics in our country, which is called STEM in many countries. STEM teaching; It is an innovative approach that brings together the piecemeal theoretical knowledge in these fields and ensures that it is applied as a whole by students and aims to transform it into a product. Survey method was used in the study. "Integrated STEM Teaching Orientation Scale" was used as a quantitative data collection tool. The scale consists of 7 Likert type, 31 items and 5 sub-dimensions. The study group consists of 344 primary school teacher which were working in Bornova district of İzmir province in 2019-2020 academic year. SPSS 25.0 package program was used in the analysis of quantitative data. According to the quantitative findings obtained from the research, it was determined that the orientation of primary school teachers' towards integrated STEM teaching was positive in the sub-dimensions of knowledge, value, attitude, subjective criteria, and perceived behavior control and behavior orientation. It was determined that STEM orientations there was no statistically difference according to gender and graduated department variables. In addition, it was observed that there was a statistically significant difference in the sub- dimension of subjective criteria according to the seniority variable.
Pendampingan Pengelolaan Keuangan UMKM dan Optimalisasi Usaha Masyarakat dalam Menghadapi Era Normal Baru di Kecamatan Ilir Barat II Kota Palembang
Authors: Ghasarma Reza , Eka Dian , Karimudin Yos , Isnurhadi Isnurhadi , Bang Pai Lian
Published: March 2022

Usaha Mikro Kecil dan Menengah (UMKM) merupakan salah satu faktor ekonomi yang berpengaruh terhadap pertumbuhan ekonomi nasional. Pada masa era tatanan baru, maka terjadi perubahan drastis pada tatanan yang ada dan telah terstruktur dengan baik. Hal ini memberi dampak pada terhambatnya aktivitas usaha termasuk UMKM. Tantangan bagi UMKM untuk tetap dapat bertahan dan terus berkembang, salah satunya dengan memahami dan menerapkan sistem manajemen keuangan. Pengelolaan keuangan melalui pembuatan laporan keuangan akan memberikan dampak positif bagi UMKM dalam mengoptimalisasikan usahanya di tengah pandemi. Pengabdian diselenggarakan di Kecamatan Ilir Barat II Kota Palembang. Kegiatan yang diselenggarakan berupa pendampingan penyusunan laporan keuangan bagi UMKM di Kecamatan Ilir Barat II Palembang. Kegiatan pengabdian berupa pembekalan teori dan penyusunan laporan keuangan sederhana. Pelaksanaan pengabdian ini memberikan manfaat yaitu: (1) memberikan informasi kepada pelaku UMKM akan manfaat menyusun anggaran usaha; (2) memberikan pemahaman perhitungan anggaran usaha serta laporan keuangan sederhana; (3) pelaku UMKM dapat memisahkan antara pengeluaran usaha dengan pengeluaran rumah tangga. Dampak (impact) dari kegiatan ini adalah menambah pengetahuan dan wawasan pelaku UMKM di Kecamatan Ilir Barat II Palembang mengenai perhitungan pelaporan keuangan yang baik dan tepat serta manfaatnya.