bluuebunny/crossref_metadata_2025 huggingface dataset:
Penyuntingan Media Online Kaidah Kebahasaan Tataran Ejaan pada Artikel Surat Kabar Merapi
Authors: Khabibah Nur
Published: January 2020

Aplikasi kaidah kebahasaan pada kenyataannya belum bisa digunakan dengan baik dalam dunia tulisan. Masih banyak kekeliruan penulisan penggunaan ejaan dalam surat kabar. Tujuan penelitian ini adalah mengetahui kesalahan penerapan kaidah kebahasaan dari segi ejaan yang terdapat pada surat kabar Merapi, memberikan perbaikan kesalahan berbahasa dari segi ejaan yang terdapat pada surat kabar Merapi, dan mengetahui seberapa banyak kesalahan penulisan dari ketiga judul artikel. Penelitian ini menggunakan penelitian kualitatif deskriptif. Penelitian kualitatif deskriptif merupakan penelitian yang mendeskripsikan tentang fenomena atau kejadian tentang kesalahan aplikasi kaidah kebahasaan pada surat kabar Merapi. Kajian yang digunakan dalam penelitian ini yaitu kajian analisis isi yang memuat tentang kesalahan berbahasa tataran ejaan yang terdapat dalam artikel surat kabar Merapi. Tiga judul yang diteliti yaitu 2.335 KK TERANCAM LONGSOR: Bantul Kekurangan Alat Pendeteksi, Atasi Kekeringan, Hargomulyo Bangun Sumur Bor, dan Sejumlah Titik Kekeringan Sulit Cari Bantuan. Ketiga judul tersebut merupakan artikel berita online dari surat kabar Merapi. Kesalahan yang ditemukan dari ketiga artikel surat kabar Merapi yaitu penulisan huruf miring, penulisan huruf kapital, penulisan bilangan, tanda koma, kata depan, tanda hubung, dan kata tidak baku. Kesalahan yang paling banyak dari ketiga artikel yaitu penulisan bilangan sebanyak 25% dan kesalahan paling sedikit yaitu penulisan huruf kapital dan tanda hubung sebanyak 2,78%.
KARAKTERISTIK PERENCANAAN PEMBANGUNAN DAERAH KEPULAUAN
Authors: gesi burhanudin
Published: January 2020

Pembangunan daerah kepulauan selama ini cendrung berorientasi "inward looking" sehingga seolah-olah kawasan perbatasan khususnya daerah kepulauan hanya menjadi halaman belakang dari pembangunan negeri ini. Akibatnya, wilayah-wilayah perbatasan dan daerah kepulauan dianggap bukan merupakan wilayah prioritas pembangunan oleh pemerintah pusat maupun daerah. • Oleh karena itu, fokus perhatian pemerintah pusat dalam mengembangkan pembangunan di daerah kepulauan, berdasarkan penetapan dana alokasi umum mestinya diperuntukan pembangunan daerah kepulauan. Sehingga dengan demikian tidak terkesan timbulnya diskriminasi dan kesenjangan sosial yang mengarah kepada disintegrasi bangsa. Persoalannya adalah ketika daerah memberikan kontribusinya berupa alokasi beban pajak yang ditetapkan pemerintah pusat dan daerah telah menyetomya ke pusat, namun demikian, kendalanya pada saat daerah hendak menerima dana alokasi umum birokrasinya menjadi sangat berbeli-belit, bahkan terjadinya tawaran untuk kontra prestasi, sehingga bukan tidak mungkin dana yang mestinya utuh totai nilai nominalnya yang hams diterima oleh daerah, bahkan yang terjadi adalah sebaliknya, karena telah dicubit oleh Jakarta sebagiannya. Ironisnya dana yang kembali ke daerah sudah tidak sebagaimana yang telah ditetapkan oleh pemerintah dan DPR RI..
Mulai Hobi hingga Mengubah Kebiasaan Hidup Meski Keringetan, Rasanya Bahagia
Authors: Purbosari Desi
Published: January 2020

Saya akan membahas tantang kasus yang awalnya habi hingga mengubah gaya hidup. Ternyata dimulai hanya sekedar hobi bisa memenuhi target yang sangat besar. Dalam kasus ini dapat menjadi sebuah inspirasi untuk bisa mengembangkan sebuah talenta. Yang hanya dimulai dari sekedar hobi bisa menjadi prestasi yang sangat luar biasa. Yang awalnya hanya sekedar ingin memenuhi hobi saja, ternyata bisa menghasilkan sebuah medali dan penghargaan yang sangat bagus. Dari kasus inilah saya ingin mengajak pembaca agar bisa ikut terinspirasi dengan apa yang telah saya buat. Sebuah bakat dan talenta haruslah terus dikembangkan dengan sebaik mungkin. Setiap orang memiliki kelebihannya masing-masing, dan kelebihan yang dimiliki oleh setiap orang haruslah terus dikembangkan dengan baik. Suatu kelebihan yang dimiliki dalam diri seseorang, pastinya sangatlah bermacam-macam dan memiliki keistimewaannya tersendiri. Dari kasus yang telah saya buat ini, pastinya sesuai dengan nilai-nilai pancasila. Karena, setiap orang yang memiliki suatu kelebihan pasti akan terus dikembangkan dengan sebaik mungkin. Dalam hal ini, kita bisa menjadikan sebuah inspirasi untuk terus maju agar bisa memperoleh sebuah prestasi yang sangat luar biasa. Hobi dan bakat merupakan suatu kelebihan yang dimiliki setiap orang. Bakat istimewa itulah yang diberikan Tuhan kepada setiap manusia.
Artikel Administrasi dan supervisi pendidikan
Authors: Yuneva Hanifah
Published: January 2020

Abstrak—Administration is a form of business and activity related to a policy arrangement in order to achieve a goal that has been set or has been designed and made before carrying out activities. And also supervision can be called Supervision which is an effort to help the development and improvement of parties in supervision so that they can carry out the tasks assigned activities efficiently and effectively. Whereas the supervisor is someone who carries out the supervision. There are two characteristics and nature of supervision that is natural and that is good. Supervision also has the functions and duties of the Coordinator, Consultant, Group Leader, Evaluator. The purpose of supervision is to provide assistance to subordinates directly, so that subordinates have sufficient stock to be able to carry out tasks or jobs with good results and orientation, train workers, lead, provide direction, and develop personal skills
STRUKTUR DAN DIMENSI IPS
Authors: erdayra rr Yenni rambe
Published: January 2020

A.Latar belakang masalah Satu kompetensi yang harus dimiliki oleh seorang guru profesional adalah kemampuan dalam mengorganisir materi pembelajaraan . Untuk melakukan tugas tersebut, Guru hendaknya memiliki keterampilan bagaimana merencanakan pembelajaran tersebut sesuai dengan karakteristik bahan materi pembelajaraan disamping karakteristik siswa, kondisi lingkungan sekolah dan masyarakat sekitarnya . Dalam makalah ini diuraikan tentang dimensi dan struktur pendidikan IPS yang akan menjadi dasar dan sumber pembelajaran khususnya dalam pengoorganisasian materi yang diselenggarakan oleh guru. Penguasaan dan pengembangan dimensi dan struktur pembelajaran dalam IPS sangat penting bagi guru karna siswa sekolah menengah diharapkan telah memiliki kemampuan berfikir abstrakdan parsial atau speslisasi serta berfikir analitis. Untuk memfasilitasi kebutuhan ini calon mahasiswa calon guru oerlu mempersiapkan model pembelajaran yang tepat yang didukung oleh kemampuan penguasaan terhadap dimensi-dimensi dan strukturnya.
UNPUBLISHED, REJECTED MANUSCRIPT NOT TO BE RESUBMITTED: Infection and ideology- Perceived vulnerability to disease predicts political conservatism
Authors: Vitriol Joseph A
Published: January 2020

Recent research on the behavioral immune system suggests that perceived vulnerability to disease is associated with greater ingroup preference, conformity, and support for established cultural practices. However, little of this research has looked at the implications of perceived vulnerability to disease for an orientation linked to many of the above outcomes: ideology. In two studies, we test the hypothesis that perceived vulnerability to disease should be associated with greater political conservatism. In Study 1, we find a relationship between perceived vulnerability to disease and increases in conservatism over time. In Study 2, we use data from the World Values Survey to demonstrate that perceived vulnerability to disease predicts a stronger preference for the political right in a large sample of respondents from a wide variety of nations. Together, these results suggest that the consequences of the behavioral immune system may extend to abstract identifications like ideology.
UNPUBLISHED, REJECTED MANUSCRIPT NOT TO BE RESUBMITTED: Acting with Conviction: On the Roles of Moral and Religious Convictions in the Minnesota Same-Sex Marriage Constitutional Amendment Vote
Authors: Vitriol Joseph A
Published: January 2020

We investigated how moral and religious convictions relate to voting on a same-sex marriage constitutional amendment. Using data collected before and after people voted on a state constitutional amendment, we examined the psychological conditions under which moral beliefs influence political choice. Voters high in purity-based moral concerns were more likely to vote to ban same-sex marriage, and voters high in fairness-based moral concerns were more likely to vote against banning same-sex marriage. These concerns were particularly important for voters with a moral or religious conviction regarding same-sex marriage. Furthermore, moral and religious convictions moderated the effect of the vote outcome on procedural and outcome fairness perceptions. These results build on prior theory and research in political and moral psychology by highlighting the importance of convictions when understanding the link between moral beliefs and political choice.
Risks of space colonization
Authors: Kovic Marko
Published: January 2020

Space colonization is humankind's best bet for long-term survival. This makes the expected moral value of space colonization immense. However, colonizing space also creates risks --- risks whose potential harm could easily overshadow all the benefits of humankind's long-term future. In this article, I present a preliminary overview of some major risks of space colonization: Prioritization risks, aberration risks, and conflict risks. Each of these risk types contains risks that can create enormous disvalue; in some cases orders of magnitude more disvalue than all the potential positive value humankind could have. From a (weakly) negative, suffering-focused utilitarian view, we therefore have the obligation to mitigate space colonization-related risks and make space colonization as safe as possible. In order to do so, we need to start working on real-world space colonization governance. Given the near total lack of progress in the domain of space governance in recent decades, however, it is uncertain whether meaningful space colonization governance can be established in the near future, and before it is too late.
Reversibility of impaired brain structures after transsphenoidal surgery in Cushing’s disease: a longitudinal study based on an artificial intelligence–assisted tool
Authors: Hou Bo , Gao Lu , Shi Lin , Luo Yishan , Guo Xiaopeng , Young Geoffrey S. , Qin Lei , Zhu Huijuan , Lu Lin , Wang Zihao , Feng Ming , Bao Xinjie , Wang Renzhi , Xing Bing , Feng Feng
Published: January 2020

OBJECTIVE

Cushing’s disease (CD) involves brain impairments caused by excessive cortisol. Whether these impairments are reversible in remitted CD after surgery has long been controversial due to a lack of high-quality longitudinal studies. In this study the authors aimed to assess the reversibility of whole-brain changes in remitted CD after transsphenoidal surgery (TSS), and its correlations with clinical and hormonal parameters, in the largest longitudinal study cohort to date for CD patient brain analysis.

METHODS

Fifty patients with pathologically diagnosed CD and 36 matched healthy controls (HCs) were enrolled in a tertiary comprehensive hospital and national pituitary disease registry center in China. 3-T MRI studies were analyzed using an artificial intelligence–assisted web-based autosegmentation tool to quantify 3D brain volumes. Clinical parameters as well as levels of serum cortisol, adrenocorticotrophic hormone (ACTH), and 24-hour urinary free cortisol were collected for the correlation analysis. All CD patients underwent TSS and 46 patients achieved remission. All clinical, hormonal, and MRI parameters were reevaluated at the 3-month follow-up after surgery.

RESULTS

Widespread brain volume loss was observed in active CD patients compared with HCs, including total gray matter (p = 0.003, with false discovery rate [FDR] correction) and the frontal, parietal, occipital, and temporal lobes; insula; cingulate lobe; and enlargement of lateral and third ventricles (p < 0.05, corrected with FDR). All affected brain regions improved significantly after TSS (p < 0.05, corrected with FDR). In patients with remitted CD, total gray matter and most brain regions (except the frontal and temporal lobes) showed full recovery of volume, with volumes that did not differ from those of HCs (p > 0.05, corrected with FDR). ACTH and serum cortisol changes were negatively correlated with brain volume changes during recovery (p < 0.05).

CONCLUSIONS

This study demonstrates the rapid reversal of total gray matter loss in remitted CD. The combination of full recovery areas and partial recovery areas after TSS is consistent with the incomplete recovery of memory and cognitive function observed in CD patients in clinical practice. Correlation analyses suggest that ACTH and serum cortisol levels are reliable serum biomarkers of brain recovery for clinical use after surgery.
In vitro and in vivo characterization of a cranial window prosthesis for diagnostic and therapeutic cerebral ultrasound
Authors: Prada Francesco , Franzini Andrea , Moosa Shayan , Padilla Frederic , Moore David , Solbiati Luigi , DiMeco Francesco , Legon Wynn
Published: January 2020

OBJECTIVE

The authors evaluated the acoustic properties of an implantable, biocompatible, polyolefin-based cranial prosthesis as a medium to transmit ultrasound energy into the intracranial space with minimal distortion for imaging and therapeutic purposes.

METHODS

The authors performed in vitro and in vivo studies of ultrasound transmission through a cranial prosthesis. In the in vitro phase, they analyzed the transmission of ultrasound energy through the prosthesis in a water tank using various transducers with resonance frequencies corresponding to those of devices used for neurosurgical imaging and therapeutic purposes. Four distinct, single-element, focused transducers were tested at fundamental frequencies of 500 kHz, 1 MHz, 2.5 MHz, and 5 MHz. In addition, the authors tested ultrasound transmission through the prosthesis using a linear diagnostic probe (center frequency 5.3 MHz) with a calibrated needle hydrophone in free water. Each transducer was assessed across a range of input voltages that encompassed their full minimum to maximum range without waveform distortion. They also tested the effect of the prosthesis on beam pressure and geometry. In the in vivo phase, the authors performed ultrasound imaging through the prosthesis implanted in a swine model.

RESULTS

Acoustic power attenuation through the prosthesis was considerably lower than that reported to occur through the native cranial bone. Increasing the frequency of the transducer augmented the degree of acoustic power loss. The degradation/distortion of the ultrasound beams passing through the prosthesis was minimal in all 3 spatial planes (XY, XZ, and YZ) that were examined. The images acquired in vivo demonstrated no spatial distortion from the prosthesis, with spatial relationships that were superimposable to those acquired through the dura.

CONCLUSIONS

The results of the tests performed on the polyolefin-based cranial prosthesis indicated that this is a valid medium for delivering both focused and unfocused ultrasound and obtaining ultrasound images of the intracranial space. The prosthesis may serve for several diagnostic and therapeutic ultrasound-based applications, including bedside imaging of the brain and ultrasound-guided focused ultrasound cerebral procedures.
Critical area for memory decline after mesial temporal resection in epilepsy patients
Authors: Kim Dahye , Kim June Sic , Jeong Woorim , Shin Min-Sup , Chung Chun Kee
Published: January 2020

OBJECTIVE

Mesial temporal lobe epilepsy (MTLE) surgery is associated with a risk of memory decline after surgery, but the effect of the extent and locus of temporal resection on postoperative memory function are controversial. The authors’ aim in this study was to confirm if selective resection is effective in preserving memory function and identify critical areas for specific memory decline after temporal resection.

METHODS

In this single-center retrospective study, the authors investigated data from patients who underwent unilateral MTLE surgery between 2005 and 2015. Data from 74 MTLE patients (60.8% of whom were female; mean [SD] age at surgery 32 years [8.91 years] and duration of epilepsy 16 years [9.65 years]) with histologically proven hippocampal sclerosis were included. Forty-two patients underwent left-sided surgery. The resection area was manually delineated on each patient’s postoperative T1-weighted images. Mapping was performed to see if the resected group, compared with the nonresected group, had worse postoperative memory in various memory domains, including verbal item, verbal associative, and figural memory.

RESULTS

Overall, 95.9% had a favorable epilepsy outcome. In verbal item memory, resection of the left lateral temporal area was related to postoperative decline in immediate and delayed recall scores of word lists. In verbal associative memory, resection of the anterior part of the left hippocampus, left parahippocampal area, and left lateral temporal area was related to postoperative decline in immediate recall scores of word pairs. Resection of the posterior part of the left hippocampus, left parahippocampal area, and left lateral temporal area was related to delayed recall scores of the same task. Similarly, in the figural memory, postoperative decline of immediate recall scores was associated with the resection of the anterior part of the right hippocampus, amygdala, parahippocampal area, and superior temporal area, and decline of delayed recall scores was related to resection of the posterior part of the right hippocampus and parahippocampal area.

CONCLUSIONS

Using voxel-based analysis, which accounts for the individual differences in the resection, the authors found a critical region for postoperative memory decline that is not revealed in the region-of-interest or groupwise comparison. Particularly, resection of the hippocampus was related to associative memory. In both verbal and visual memory, resection of the anterior part of the hippocampus was associated with immediate recall, and resection of the posterior part of the hippocampus was associated with delayed recall. Therefore, the authors’ results suggest that selective resection may be effective in preserving postoperative memory decline.
MEG3/MIR-376B-3P/HMGA2 axis is involved in pituitary tumor invasiveness
Authors: Zhu Dimin , Xiao Zheng , Wang Zongming , Hu Bin , Duan Chengbin , Zhu Ziyan , Gao Nailin , Zhu Yonghong , Wang Haijun
Published: January 2020

OBJECTIVE

To date, long noncoding RNAs (lncRNAs) have proven to function as key regulators in tumorigenesis. Among these lncRNAs, MEG3 displays low levels in various neoplasms and tumor cell lines. However, the regulatory mechanism of MEG3 and MIR-376B-3P, one of the microRNAs from downstream gene clusters of the DLK1-MEG3 locus, remains insufficiently defined.

METHODS

The authors used quantitative real-time polymerase chain reaction analysis to analyze whether decreased MEG3 and MIR-376B-3P expression levels were associated with the invasiveness of clinical nonfunctioning pituitary adenomas (CNFPAs) in 30 patients. Furthermore, functional experiments unveiled the pathophysiological role of MEG3, MIR-376B-3P, and HMGA2 in pituitary-derived folliculostellate (PDFS) cell lines. Moreover, dual-luciferase reporter assay, Western blot analysis, and immunofluorescence were applied to reveal the correlations among MEG3, MIR-376B-3P, and HMGA2.

RESULTS

MEG3 and MIR-376B-3P were decreased in patients with CNFPA, and their transcriptional levels were highly associated with invasive CNFPAs. Moreover, excessive expression of MEG3 and MIR-376B-3P inhibited tumorigenesis and promoted apoptosis in PDFS cells. Importantly, the authors found that MEG3 acted as an enhancer of MIR-376B-3P expression. Furthermore, as a target gene of MIR-376B-3P, HMGA2 served as an oncogene in pituitary adenoma and could be negatively regulated by MEG3 via enriching MIR-376B-3P.

CONCLUSIONS

This study offers a novel mechanism of an MEG3/MIR-376B-3P/HMGA2 regulatory network in CNFPAs, which may become a breakthrough for anticancer treatments.
Endoscopic approaches to orbital lesions: case series and systematic literature review
Authors: Zoli Matteo , Sollini Giacomo , Milanese Laura , La Corte Emanuele , Rustici Arianna , Guaraldi Federica , Asioli Sofia , Cirillo Luigi , Pasquini Ernesto , Mazzatenta Diego
Published: January 2020

OBJECTIVE

Surgical treatment of orbital lesions is challenging because complex approaches with a high risk of postoperative sequelae are required. Recently, minimally invasive endoscopic approaches through endonasal (EEA) and transpalpebral (ETP) routes have been proposed. The objective of this study was to assess outcomes of EEA and ETP in the authors’ series of patients with orbital lesions.

METHODS

Data from all patients who underwent operations for an orbital tumor through an endoscopic approach at the authors’ institution from 2002 to 2018 were retrospectively collected. All patients underwent preoperative MRI and ophthalmological evaluation, which was repeated 3 months after surgery and then at regular follow-up intervals. A systematic review of the literature was also performed using Medline, Embase, and Web of Science databases.

RESULTS

The series includes 23 patients (14 males); the mean patient age was 48 ± 23.9 years. Most of the lesions were intraconal (n = 19, 83%). The more frequent histotype was cavernous hemangioma (n = 5, 22%). Exophthalmos was the most common symptom (21 of 23 patients). EEA was performed in 16 cases (70%) and ETP in 7 (30%). The aim of the surgery was achieved in 94% of the cases after an EEA (successful biopsy in 5 of 6 cases and radical resection in all 10 remaining patients), and in 86% after an ETP (successful biopsy in 2 cases and radical tumor resection in 4 of 5 cases). Complications consisted of 3 cases (13%) of transitory diplopia. One recurrence (4%) was observed at follow-up (mean 59 ± 55 months).

CONCLUSIONS

The EEA and ETP have demonstrated to be safe and effective for tumors located respectively in medial and lateral quadrants, permitting one to approach orbital lesions endoscopically at 360°. Innovative surgical tools, including intraoperative ultrasonography, may be useful to potentially reduce surgical morbidity. Larger series are needed to validate these preliminary suggestions.
Safety and feasibility of multiple blood-brain barrier disruptions for the treatment of glioblastoma in patients undergoing standard adjuvant chemotherapy
Authors: Park So Hee , Kim Myung Ji , Jung Hyun Ho , Chang Won Seok , Choi Hyun Seok , Rachmilevitch Itay , Zadicario Eyal , Chang Jin Woo
Published: January 2020

OBJECTIVE

Glioblastoma (GBM) remains fatal due to the blood-brain barrier (BBB), which interferes with the delivery of chemotherapeutic agents. The purpose of this study was to evaluate the safety and feasibility of repeated disruption of the BBB (BBBD) with MR-guided focused ultrasound (MRgFUS) in patients with GBM during standard adjuvant temozolomide (TMZ) chemotherapy.

METHODS

This study was a prospective, single-center, single-arm study. BBBD with MRgFUS was performed adjacent to the tumor resection margin on the 1st or 2nd day of the adjuvant TMZ chemotherapy at the same targets for 6 cycles. T2*-weighted/gradient echo (GRE) MRI was performed immediately after every sonication trial, and comprehensive MRI was performed at the completion of all sonication sessions. Radiological, laboratory, and clinical evaluations were performed 2 days before each planned BBBD.

RESULTS

From September 2018, 6 patients underwent 145 BBBD trials at various locations in the brain. The authors observed gadolinium-enhancing spots at the site of BBBD on T1-weighted MRI in 131 trials (90.3%) and 93 trials (64.1%) showed similar spots on T2*-weighted/GRE MRI. When the 2 sequences were combined, BBBD was observed in 134 targets (92.4%). The spots disappeared on follow-up MRI. There were no imaging changes related to BBBD and no clinical adverse effects during the 6 cycles.

CONCLUSIONS

This study is the first in which repetitive MRgFUS was performed at the same targets with a standard chemotherapy protocol for malignant brain tumor. BBBD with MRgFUS was performed accurately, repeatedly, and safely. Although a longer follow-up period is needed, this study allows for the possibility of other therapeutic agents that previously could not be used due to the BBB.

Clinical trial registration no.: NCT03712293 (clinicaltrials.gov)
Predictors of recurrence and high growth rate of residual meningiomas after subtotal resection
Authors: Materi Joshua , Mampre David , Ehresman Jeff , Rincon-Torroella Jordina , Chaichana Kaisorn L.
Published: January 2020

OBJECTIVE

The extent of resection has been shown to improve outcomes in patients with meningiomas. However, resection can be complicated by constraining local anatomy, leading to subtotal resections. An understanding of the natural history of residual tumors is necessary to better guide postsurgical management and minimize recurrence. This study seeks to identify predictors of recurrence and high growth rate following subtotal resection of intracranial meningiomas.

METHODS

Adult patients who underwent primary surgical resection of a WHO grade I meningioma at a tertiary care institution from 2007–2017 were retrospectively reviewed. Volumetric tumor measurements were made on patients with subtotal resections. Stepwise multivariate proportional hazards regression analyses were performed to identify factors associated with time to recurrence, as well as stepwise multivariate regression analyses to assess for factors associated with high postoperative growth rate.

RESULTS

Of the 141 patients (18%) who underwent radiographic subtotal resection of an intracranial meningioma during the reviewed period, 74 (52%) suffered a recurrence, in which the median (interquartile range, IQR) time to recurrence was 14 (IQR 6–34) months. Among those tumors subtotally resected, the median pre- and postoperative tumor volumes were 17.19 cm3 (IQR 7.47–38.43 cm3) and 2.31 cm3 (IQR 0.98–5.16 cm3), which corresponded to a percentage resection of 82% (IQR 68%–93%). Postoperatively, the median growth rate was 0.09 cm3/year (IQR 0–1.39 cm3/year). Factors associated with recurrence in multivariate analysis included preoperative tumor volume (hazard ratio [HR] 1.008,95% confidence interval [CI] 1.002–1.013, p = 0.008), falcine location (HR 2.215, 95% CI 1.179–4.161, p = 0.021), tentorial location (HR 2.410, 95% CI 1.203–4.829, p = 0.024), and African American race (HR 1.811, 95% CI 1.042–3.146, p = 0.044). Residual volume (RV) was associated with high absolute annual growth rate (odds ratio [OR] 1.175, 95% CI 1.078–1.280, p < 0.0001), with the maximum RV benefit at < 5 cm3 (OR 4.056, 95% CI 1.675–9.822, p = 0.002).

CONCLUSIONS

By identifying predictors of recurrence and growth rate, this study helps identify potential patients with a high chance of recurrence following subtotal resection, which are those with large preoperative tumor volume, falcine location, tentorial location, and African American race. Higher RVs were associated with tumors with higher postoperative growth rates. Recurrences typically occurred 14 months after surgery.
Subcutaneous sumatriptan: association with decreases in postoperative pain and opioid use after elective cranial surgery
Authors: Patel Kunal S. , Laiwalla Azim N. , DiCesare Jasmine A. T. , Garrett Matthew C. , Wang Anthony C.
Published: January 2020

OBJECTIVE

Sumatriptan, a serotonin receptor agonist, has been used in the management of primary headache disorders and has been shown to affect trigeminal dural afferents. There is limited literature on the safety and efficacy of sumatriptan for postcraniotomy pain management. This study aimed to identify whether subcutaneous sumatriptan is a safe and efficacious pain management strategy after elective craniotomy.

METHODS

The authors retrospectively reviewed patients who underwent supratentorial or suboccipital craniotomy between 2016 and 2019 that was performed by a single provider at a single institution to identify patients given subcutaneous sumatriptan in the postoperative period. Pain scores and intravenous and oral opioid use were compared in patients with (n = 15) and without (n = 45) sumatriptan administration.

RESULTS

Patients with and without sumatriptan administration had no significant differences in baseline characteristics or surgery type. There were no sumatriptan-related complications. The average pain score decreased from 3.9 to 1.3 within 1 hour after sumatriptan administration (p = 0.014). In both adult and pediatric patients there was decreased postoperative pain (adults: pain score of 1.1 vs 7.1, p < 0.001; pediatric: 1.1 vs 3.9, p = 0.007) within the first 48 hours. There were decreases in intravenous opioid use, length of intravenous opioid use, maximum dose of intravenous opioid used, oral opioid use, length of oral opioid use, and maximum dose of oral opioid used in both adult and pediatric patients.

CONCLUSIONS

The authors identified subcutaneous sumatriptan as a safe and efficacious tool for postoperative pain management after craniotomy. Large multicenter randomized controlled studies are needed to further evaluate the specific role of sumatriptan in postoperative pain management after craniotomy.
Multitarget deep brain stimulation for clinically complex movement disorders
Authors: Parker Tariq , Raghu Ashley L. B. , FitzGerald James J. , Green Alexander L. , Aziz Tipu Z.
Published: January 2020

Deep brain stimulation (DBS) of single-target nuclei has produced remarkable functional outcomes in a number of movement disorders such as Parkinson’s disease, essential tremor, and dystonia. While these benefits are well established, DBS efficacy and strategy for unusual, unclassified movement disorder syndromes is less clear. A strategy of dual pallidal and thalamic electrode placement is a rational approach in such cases where there is profound, medically refractory functional impairment. The authors report a series of such cases: midbrain cavernoma hemorrhage with olivary hypertrophy, spinocerebellar ataxia-like disorder of probable genetic origin, Holmes tremor secondary to brainstem stroke, and hemiballismus due to traumatic thalamic hemorrhage, all treated by dual pallidal and thalamic DBS. All patients demonstrated robust benefit from DBS, maintained in long-term follow-up. This series demonstrates the flexibility and efficacy, but also the limitations, of dual thalamo-pallidal stimulation for managing axial and limb symptoms of tremors, dystonia, chorea, and hemiballismus in patients with complex movement disorders.
Uncomplicating the Idea of Wilderness
Authors: Duclos Joshua S.
Published: January 2020

In this paper I identify and respond to four persistent objections to the idea of wilderness: empirical, cultural, philosophical and environmental. Despite having dogged the wilderness debate for decades, none of these objections withstands scrutiny; rather they are misplaced criticisms that hinder fruitful discussion of the philosophical ramifications of wilderness by needlessly complicating the idea itself. While there may be other justifiable concerns about the idea of wilderness, it is time to move beyond the four discussed in this paper.
Under the Volcano: Mount Mayon and Co-Volcanic Societies in the Philippines
Authors: Bankoff Greg
Published: January 2020

Rich volcanic soils have long attracted human settlements, which have traded the risk of eruption against the benefits of higher agricultural yields. Yet little research has been done on how societies have normalised the risks and adapted to living in proximity to volcanoes, or how those modifications, in turn, might have influenced the effects of eruptions and their consequent hazards. In short, people have co-evolved with volcanoes to create 'co-volcanic societies'. By looking closely at the Philippines and focusing on one region of southern Luzon around Mount Mayon, this article addresses the question of how people and the volcano have 'co-adapted' to living in proximity to one another over time. It also suggests that to make societies more resilient to volcanic hazards, a better understanding of this relationship is required not only to improve current disaster risk reduction policies but even to inform everyday urban planning and civil engineering decisions.
Event, Process and Pulse: Resituating Floods in Environmental Histories of South Asia
Authors: D'Souza Rohan
Published: January 2020

The notion of the flood in South Asia is no longer solely characterised as the archetypal natural disaster. This perceptual shift, as this article will point out, draws from a conceptual shift within the field of environmental histories of South Asia. In the course of exploring and debating ideas about environmental change, environmental historians have drastically reconsidered the role and impacts of flooding in South Asia through three distinct narrative frameworks: (i) extreme hydraulic events; (ii) geomorphological process; and (iii) biological pulses. Environmental history as a field has thus helped to flesh out and radically revise our understanding of flooding, which has changed from previously being seen as an ahistorical calamitous event to instead providing contexts for revealing complex relationships between geomorphological processes, biological pulses and livelihood strategies. The notion of the flood in South Asia, consequently, is now acknowledged as an ecological force that is mediated by social, cultural and political interventions rather than exclusively borne out as an effect of nature.
Earthquakes and the Environmental Transformation of a Floodplain Landscape: The Brahmaputra Valley and the Earthquakes of 1897 and 1950
Authors: Saikia Arupjyoti
Published: January 2020

Two major earthquakes in 1897 and 1950 had a deep impact upon the environment and humans in north-east India. The massive seismic disturbance of 1897 played a crucial role in shaping the physical history of this region. Seismologists have observed that this earthquake holds a 'prominent place among the great earthquakes of the world'. Another earthquake in 1950 disturbed the region's physical setting. This article will examine how these earthquakes transformed the landscape of Assam, and, in so doing, affected the lives and livelihoods of human communities. It will detail the various geological and hydrological consequences of earthquakes, which included the creation of floods, landslides, fissures, sand vents and artificial river dams. It will demonstrate how these changes affected Assamese agriculturalists and fishing communities. In so doing, it will shift the historiography of earthquakes away from a largely urban focus to examine the rural experiences of seismic activity.
The Fight Against Heaven-Sent Insects: Dealing with Locust Plagues in the Emirate of Bukhara
Authors: Dağyeli Jeanine Elif
Published: January 2020

The late nineteenth and early twentieth centuries were a time of crisis and change for Central Asian societies. Land reclamation, an agricultural shift to cash crops, trophy hunting and war led to the deterioration of a fragile ecosystem and encouraged outbreaks of agricultural pests. Among the most conspicuous were locust outbreaks which troubled the Emirate of Bukhara during this period. Large swarms destroyed most of the crops, making the population dependent on grain imports. Locusts were a well-known pest although traditional land use practices seem to have constrained long-term outbreaks. Dealings with the insects once they appeared were modest, though. The establishment of Russian colonial rule in the region deeply interfered with existing conceptions of human-environment relations and increased the pressure on resources. Combating locusts was a controversial subject between colonial and Bukharan officials as well as their subjects: like other kinds of natural disasters that were beyond human control, locusts were perceived as a heaven-sent visitation in Bukhara, turning combat into an activity against divinity. The fight against locusts reached a political dimension around 1900 when the Russian colonial administration tried to pressurise the Bukharans into using modern insecticides and blamed their superstition for the resistance they met. This article examines the reciprocal effects of changes in land management and pest outbreaks, and the controversies between traditional responses, colonial demands and religious conceptualisations in relation to combating locusts.
Principle of dialogue in Mikhail Bakhtin’s poetics
Authors: Trong Hoang Linh Phan
Published: January 2020

Mikhail Bakhtin (1895 - 1975) had a great influence on the history of modern poetics in the world. From the 1980s onwards, the adoption of Bakhtin's poetics was of great significance, contributing to the development of poetics in Vietnam in nearly four decades. One of the essential foundations for his theory is the principle of dialogue. However, applying the principle of dialogue in a systematic relationship with Bakhtin's academic legacy, especially its relation to the principle of carnaval, has never become easy for a consensus. The duty of this essay is to analyze the principle of dialogue in a systematic view. Dialogue is first a linguistic principle proposed on the basis of counter-argument of the linguistic theory of F.D. Saussure. The carnaval principle is a cultural basis for applying the principle of dialogue into the study of literature. By connecting these two principles to a system, Bakhtin wanted to promote the study of literature to cultural poetics. Applying the principle of dialogue for study Dostoievski’s work, he discovered the kind of novel that had never appeared before: polyphonic novel. This type of novel contains a new structure in the relationship between the author and the character, and if not based on the principle of dialogue, it is difficult to understand its full value.
Efektifitas Simulasi Resusitasi Jantung Paru Terhadap Kemampuan Penatalaksanaan Resusitasi Jantung Paru Anggota Brimob
Authors: Kusumawati Prima Dewi , Jaya Adetya Wahyu Dwi
Published: January 2020

Pendahuluan: Kurangnya kemampuan masyarakat dalam melakukan pertolongan pertama pada korban yang mengalami henti jantung disebabkan karena masih kurang pengetahuan yang dimiliki masyarakat khususnya tentang cara melakukan resuistasi jantung paru sehingga angka kematian akibat henti jantung meningkat.
Tujun: mengetahui tingkat efektifitas simulasi resusitasi jantung paru terhadap kemampuan penatalaksanaan resusitasi jantung paru Anggota Brimob
Desain: desain penelitian adalah pra eksperimental dengan pendekatan one-group pre test post test. Responden. Populasi semua anggota Brimob di Kompi 1 Batalyon C Pelopor Satbrimob Polda Jatim sebanyak 100 orang, dengan teknik accidental sampling didaptkan sampel sebanyak 25 responden.
Hasil: penelitian menunjukan seluruh Anggota Brimob memiliki kemampuan dengan kategori kurang terampil dalam melakukan resusitasi jantung paru sebelum dilakukan simulasi yaitu sebanyak 25 (100%) responden, Hampir seluruh Anggota Brimob memiliki kemampuan dengan kategori terampil dalam melakukan resusitasi jantung paru setelah dilakukan simulasi yaitu sebanyak 22 (88,0%). Hasil analisis data menunjukan bahwa tingkat signifikansi nilai p = 0,000 sehingga H1 diterima.
Kesimpulan: ada pengartuh simulasi Resusitasi Jantung Paru terhadap kemampuan penatalaksanaan Resusitasi Jantung Paru (RJP) Anggota Brimob di Kompi 1 Batalyon C Pelopor Satbrimob Polda Jatim. Ketrampilan seseorang perlu diasah agar semakin trampil dalam melakukan bantuan hidup dasar bagi Anggota Brimob. Dengan diberikannya simulasi anggota brimob bukan hanya mendengar tetapi juga dapat melihat secara langsung tindakan yang dapat dilakukan ketika menemukan korban dengan henti jantung.
Analisis Kepatuhan Antenatal Care (Anc) Terhadap Kejadian Komplikasi Kehamilan Di Puskesmas Tiudan Kecamatan Gondang Kabupaten Tulungagung
Authors: Mahendra Agustian Dwi , Hidajaturrokhmah Nur Yeny , Anggraeni Suci
Published: January 2020

Pendahuluan: Kepatuhan ibu hamil untuk melakukan Antenatal care sangat penting karena dapat mengurangi angka komplikasi kehamilan. Akan tetapi prevalensi ibu hamil untuk melakukan Antenatal Care sangat rendah.
Tujuan: Tujuan penelitian ini menganalisis kepatuhan Antenatal Care (ANC) terhadap kejadian komplikasi kehamilan di Puskesmas Tiudan Kecamatan Gondang Kabupaten Tulungagung.
Desain: Desain penelitian ini adalah observasional dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah semua ibu hamil yang ada di Puskesmas Tiudan Kecamatan Gondang Kabupaten Tulungagung sejumlah 45 responden. Sampel diambil secara purposive sampling didapatkan 30 responden . Data yang telah terkumpul diolah dengan uji statistik chi square dengan kemaknaan α =0,05.
Hasil: Hasil penelitian menunjukkan bahwa dari 30 responden, sebagian besar dari responden memiliki kepatuhan ANC yang patuh, yaitu 19 responden (63,3%) dan sebagian besar responden tidak mengalami kejadian komplikasi saat hamil, yaitu 22 responden (73,3%). Hasil penelitian ini yaitu ada hubungan kepatuhan Antenatal Care (ANC) terhadap kejadian komplikasi kehamilan di Puskesmas Tiudan Kecamatan Gondang Kabupaten Tulungagung (nilai p-value = 0,002) dengan uji chi square.
Kesimpulan: Kepatuhan ibu hamil untuk melakukan Antenatal care sangat penting karena akan dapat membantu mengurangi komplikasi kehamilan yang dapat mempengaruhi angka kematian ibu dan bayi.
Pengembangan telenursing N-SMSI (Ners - Short Message Service Intervention) dalam perawatan pasien TB (Tuberkulosis) post rawat di Rumah Sakit
Authors: Anggana Renditya , Ikasari Filia Sofiani
Published: January 2020

Pendahuluan: Tuberkulosis (TB) masih menjadi penyakit infeksi menular yang mematikan di masyarakat. Pasien TB dengan rawat jalan berkemungkinan besar untuk mengalami putus obat yang dapat menyebabkan Multi Drug Resisten Tuberkulosis (MDR-TB). Ners-Short Message Service Intervention (N-SMSI) merupakan salah satu sistem informasi yang dapat dikembangkan untuk mencegah terjadinya MDR-TB.
Tujuan: Penulisan artikel ini adalah untuk memaparkan dan menganalisis pengembangan telenursing N-SMSI sebagai salah satu sistem informasi untuk melakukan monitoring dalam perawatan pasien TB yang dapat membantu pasien TB dalam mencapai kesembuhan dengan cara yang efektif dan efisien.
Metode: Penulisan artikel ini adalah studi literatur dengan menggunakan berbagai literature terkait penerapan N-SMSI terutama dalam pencegahan MDR-TB.
Hasil: Hasilnya menunjukkan bahwa N-SMSI dapat dimanfaatkan dalam pemantauan kepatuhan pasien dalam konsumsi OAT. Selain itu, dapat menjadi rekomendasi untuk penerapan N-SMSI pada pasien TB rawat jalan, sehingga memudahkan aktivitas monitoring oleh tenaga kesehatan dalam pencegahan MDR-TB.
Kesimpulan: TB merupakan salah satu penyakit yang perlu mendapatkan pengawasan ekstra dalam menjalankan terapi medikasinya. Hal tersebut dapat dilakukan dengan N-SMSI yang merupakan salah satu telenursing yang dapat dimanfaatkan meskipun dalam penelitiannya masih pada kasus TB paru, tidak menutup kemungkinan pada kasus TB lain atau bahkan kasus penyakit lain.
Tingkat Pendidikan dan Pengetahuan Ibu Hamil dengan Status Anemia
Authors: Chandra Filius , Junita Dini Dini , Fatmawati Tina Yuli
Published: January 2020

Pendahuluan: Kehamilan adalah salah satu masa yang terpenting untuk pertumbuhan janin. Kebutuhan akan zat gizi juga meningkat sejalan dengan pertambahan umur kehamilan. Asupan gizi yang tidak mencukupi pada ibu hamil dapat menyebabkan anemia. Ibu hamil  dengan kekurangan asupan gizi dapat meningkatkan terjadinya resiko keguguran bahkan kematian perinatal.
Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui hubungan pendidikan dan pengetahuan terhadap status anemia ibu hamil di Puskesmas Simpang Kawat Kota Jambi.
Metode Penelitian ini merupakan penelitian deskriptif korelatif dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah seluruh ibu Hamil trimester I dan II di Puskesmas Simpang awat Kota Jambi. Sampel dengan menggunakan teknik total sampling berjumlah 41 responden, Analisa data yang digunakan adalah analisa Univariat dan Bivariat dengan uji statistic Chi Square.
Hasil: Hasil uji statistis diketahui ada hubungan yang bermakna antara pendidikan dan Pengetahuan responden dengan status anemia ibu hamil dengan nilai p-value 0.000 (p<0.005).
Kesimpulan: Pentingnya dilaksanakan edukasi kesehatan tentang anemia selama kehamilan sehingga tidak terjadi komplikasi pasca kehamilan.
Peran Siswa Sekolah Dasar dalam Perubahan Perilaku Pembuangan Sampah Organik dan Pemanfaatan Pembuangan Akhir
Authors: Daniah Daniah
Published: January 2020

Pendahuluan: Sampah dapat menimbulkan kesehatan dan keselamatan linkungan, bila sampah tidak dikelola dengan baik.
Tujuan: Tujuan dalam penelitian ini adalah siswa SD dapat mengetahui membedakan sampah organik dan non organik, siswa SD juga agar dapat melakukan perubahan dalam memuang sampah ke tempat pemuangan akhir.
Desain: Jenis penelitian ini adalah kuantitatif, menggunakan Quasi Eksperiment. Pengukuran dilakukan sebanyak 2 kali   Pre dan post. Dilakukan di SDN Sukaluyu Kec.Teluk Jambe Kab. Karawang. Populasi dalam penelitian ini Siswa Kelas 6 sebanyak 51 orang.
Hasil: Hasil analisis Adanya pengaruh intervensi terhadap pengetahuan meningkat sebesar 8,3 setelah intervensi. Hasil uji statistik menunjukan nilai P sebesar 0,000 yang berarti intervensi memiliki pengaruh yang signifikan terhadap peningkatan pengetahuan. sikap meningkat sebesar 5,1 setelah intervensi. Hasil uji statistik menunjukan nilai P sebesar 0,000 yang berarti intervensi memiliki pengaruh yang signifikan terhadap peningkatan skor sikap.
Kesimpulan: Hasil penelitian disimpulkan Rata-rata adanya pengaruh kenaikan pengetahuan setelah dilakukan intervensi, dan adanya peruahan perilaku.
Nurse's Perception of Patient Safety Culture in an Effort to Improve Service Quality in the Operating Room of Riau Province Hospital
Authors: Yulisnawati  , Zulfendri  , Siti Saidah Nasution
Published: January 2020

The aim of the study is to find out Nurse's perception of patient safety culture in an effort to improve service quality. This study uses qualitative research methods with a phenomenological approach. The result of the study is obtained that the informants assume that the socialization carried out by the hospital in the context of increasing knowledge related to patient safety is not effective. Education and training for patient safety is carried out continuously to increase knowledge, improve and maintain staff competence. While the socialization carried out by the hospital did not have much influence to increase the informant's knowledge related to patient safety.
The Decision of Married Woman to Inspect IVA Test in Deli Serdang, Indonesia
Authors: Nurbaity  , Zulfendri  , Rochadi R. Kintoko
Published: January 2020

This study aims to find out the decision of married woman to inspect IVA Test in Deli Serdang, Indonesia. This type of research is an analytical survey research with cross sectional approach (Arikunto, 2010), which aims to determine the relationship of power relations with the low coverage of IVA Test coverage. The result shows that the dominance of power in the household, socio-economic that has a relationship with the decision making to conduct an IVA test in Deli Serdang Regency, It can be concluded several things.