bluuebunny/crossref_metadata_2025 huggingface dataset:
Key Priorities of Organizational Solutions for High-Tech Business Management
Authors: Baurina Svetlana
Published: January 2025

This article is devoted to the key priorities of organizational solutions for hightech business management. The essence of the development strategy is revealed. The key stages of strategy development and implementation are specified: strategic analysis, mission definition and strategic goals, development of strategic alternatives, strategy selection, strategy implementation, monitoring and control. The tools for developing and implementing the strategy inherent in each of the stages have been identified. The specifics of strategic management in the high-tech sector of the economy are described. The experience of strategic development of Russian high-tech industries in the field of IT, telecommunications, instrument making, aerospace and nuclear industry is analyzed. Key areas and activities within the strategic development of the organization were identified. The organizational structure and rules of operation of the Project Office responsible for coordination and methodological support of strategic projects and programs are presented.
Świętość księdza Józefa Sebastiana Pelczara w duszpasterskiej codzienności Sambora i Wojutycz – emanacja na pokolenia
Authors: Szczych Jan
Published: January 2025

W roku 2024 mija sto lat od śmierci św. Józefa Sebastiana Pelczara, biskupa przemyskiego (1900–1924). Po otrzymaniu święceń kapłańskich w katedrze przemyskiej w 1864 r., ks. Pelczar został mianowany wikariuszem parafii w Samborze. Był to okres jego pierwotnej gorliwości, inspirowanej chęcią dalszej nauki w Wiecznym Mieście. Po powrocie ze studiów rzymskich, ks. dr Pelczar został ponownie posłany do pracy duszpasterskiej: najpierw do Wojutycz, a następnie znowu do Sambora. Jego drugi pobyt na parafiach ukazuje ks. dra Pelczara jako kapłana pokornego i posłusznego, który pomimo niedowartościowania z oddaniem pełnił zlecone mu obowiązki. 
Ks. Pelczar wiernie przestrzegał przyrzeczenia posłuszeństwa władzy duchownej i nie wytyczał sobie swojej życiowej drogi w Kościoła. Jako dobrze uformowany kapłan pokornie poddawał się projektom Opatrzności. Całe jego bogate życie słusznie uzasadnia, że proszącemu, Pan Bóg zawsze daje więcej łask, niż on sam oczekuje (zob. 2 Kor 9, 8).
Reading the Myth and Reality of Vrindavan
Authors:   Department of Humanities, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Haryana, India, Yadav Manisha , Rani Rekha ,   Department of Humanities, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Haryana, India
Published: January 2025

Vrindavan is commonly referred to as the abode of the mythic-literary-celestialcouple Radha-Krishna, and is an epicenter of religious and spiritual questing and global sociocultural hub. Huge numbers of visitors come to the town to frequently and regularly express their faith. For them, Vrindavan is a metaphor of love, bliss and spirituality. Visiting Vrindavan can be seen as going to meet Krishna. However, Vrindavan is not only a religious center, it is also just like any other town, with many dimensions to its character. As a living organism, Vrindavan has its body, its soul, its beauty, its ugliness and its ordinariness. It breathes; it talks and feels pain as well. But this material reality with all its complexities is generally overshadowed by the brightness of its religious halo. This mythical and metaphoric construct of Vrindavan has veiled its real and complete identity. There must be a town in ‘Vrindavan’ and ‘Vrindavan’ in the town. This article attempts to describe this dual character.
Compact deep-groove-assisted bends on SiN platform for monolithic integrated laser
Authors: Zhang Ziyao , Skandalos Ilias , Ma Rui , Chen Minjia , Sun Bohao , Zhong Chuan , Gardes Frederic , Cheng Qixiang , Penty Richard
Published: January 2025

To build a photonic integration platform that incorporates monolithically integrated light sources which require minimized loss and reflection, a micro-meter scale passive layer is needed in addition to the III-V layer. Low temperature plasma-enhanced chemical vapor deposition (PECVD) silicon nitride (SiN) is a promising candidate, owing to its back-end-of-line (BEOL) integration capabilities, along with its amorphous structure that allows the growth of defect-free thick layers. In view of the III-V layer stack, the optimized SiN waveguides are thick and in a rib formation. However, bends on this thick SiN platform suffer from high radiation losses, resulting in the need for a bending radius as large as 800 µm that poses challenges for compact photonic integrated circuits (PICs). This paper describes and demonstrates a novel SiN bending structure with a deep etched groove along the outer side. This structure significantly reduces the bending radii to 37 µm with a bending loss of 0.1 dB/90°. A compact micro-ring resonator (MRR) with deep etched grooves is also investigated, exhibiting a substantial enhancement in the free spectral range (FSR) compared with the rib waveguide MRRs, while offering a passband of 39.1 GHz. These notable performance improvements pave the way for compact integrated emitters on a single substrate.
Hybrid phase-correction metasurfaces for accurate near-field manipulation
Authors: Qiao Hui , Zhuge Xiaodong , Yang Junhui , Xiong Mengfei
Published: January 2025

Although metasurface has attracted significant attention in recent years due to its ability to manipulate electromagnetic waves, discrepancies are often observed when comparing the designed and realized near-field performances. Among various contributing factors, one important issue is related to the fact that the elements arranged on a metasurface are typically designed under the assumption of normal incident excitation, whereas in practice they are actually excited at various oblique incidence angles depending on the element's relative position to the feed antenna. This introduces amplitude and phase errors in the reflection or transmission coefficients of the elements within the metasurface, thereby affecting its overall performance. In this paper, a hybrid phase-correction method is proposed to compensate for the effect of oblique incidence on metasurfaces. The actual oblique incidence angles are decomposed into elevation and azimuth directions: In the elevation direction, the element characteristics under oblique incidence replace those under normal incidence, while in the azimuth direction, element rotation is introduced to compensate for the local effects. Near-field focusing and holographic metasurfaces are designed to verify the proposed hybrid phase-correction method. Full-wave electromagnetic simulations show that the proposed metasurface has the advantage in sidelobe levels without significant costs in terms of the amount of element-level computations. Finally, the near-field focusing metasurfaces are fabricated, and the measured results further demonstrate the potential of the proposed design for accurate near-field manipulation.
BuDDI: Bulk Deconvolution with Domain Invariance to predict cell-type-specific perturbations from bulk
Authors: Davidson Natalie R. , Zhang Fan , Greene Casey S.
Published: January 2025

While single-cell experiments provide deep cellular resolution within a single sample, some single-cell experiments are inherently more challenging than bulk experiments due to dissociation difficulties, cost, or limited tissue availability. This creates a situation where we have deep cellular profiles of one sample or condition, and bulk profiles across multiple samples and conditions. To bridge this gap, we propose BuDDI (BUlk Deconvolution with Domain Invariance). BuDDI utilizes domain adaptation techniques to effectively integrate available corpora of case-control bulk and reference scRNA-seq observations to infer cell-type-specific perturbation effects. BuDDI achieves this by learning independent latent spaces within a single variational autoencoder (VAE) encompassing at least four sources of variability: 1) cell type proportion, 2) perturbation effect, 3) structured experimental variability, and 4) remaining variability. Since each latent space is encouraged to be independent, we simulate perturbation responses by independently composing each latent space to simulate cell-type-specific perturbation responses. We evaluated BuDDI’s performance on simulated and real data with experimental designs of increasing complexity. We first validated that BuDDI could learn domain invariant latent spaces on data with matched samples across each source of variability. Then we validated that BuDDI could accurately predict cell-type-specific perturbation response when no single-cell perturbed profiles were used during training; instead, only bulk samples had both perturbed and non-perturbed observations. Finally, we validated BuDDI on predicting sex-specific differences, an experimental design where it is not possible to have matched samples. In each experiment, BuDDI outperformed all other comparative methods and baselines. As more reference atlases are completed, BuDDI provides a path to combine these resources with bulk-profiled treatment or disease signatures to study perturbations, sex differences, or other factors at single-cell resolution.
Neo-liberal ideologies and the contested formation of Mercamadrid or the shifting visibilities of urban infrastructure
Authors: Martínez Jr. Michael L.
Published: January 2025

This article examines the contested formation of Spain’s largest wholesale food distribution centre, Mercamadrid, in relation to wider projects of neo-liberal restructuring in Madrid, Spain, during the second half of the twentieth century. It first links the installations at Mercamadrid to efforts undertaken by the Franco Regime (1939–75) to liberalize the nation’s fledgling economy. To draw out some of the path-dependent legacies of Francoist urbanism, the article then explores a supply-chain dispute that unfolded at the wholesale complex during the Transition (1975–82) and early democratic periods (1982–96). A close reading of the so-called Fruit Sellers’ War of 1986 will show how urban elites symbolically framed Mercamadrid’s urban landscape as a bastion of consumer rights. The focus thereafter moves to the Arganzuela district, where prior to Mercamadrid’s construction the city’s original trio of municipal markets were previously located. This to show that a series of large-scale urban development projects there – the Atocha train station, the Matadero Madrid arts and cultural centre, and the Madrid Río Park – transformed the once-polluted industrial and service district into an iconic landscape of a burgeoning global city. The shifting narratives surrounding the purpose and function of Mercamadrid provide insights into the powerful ways that capital shapes the geographies of our cities to legitimize its own self-serving growth ideologies.
Istanbul’s urban affects: Cosmopolitanism, secularism and ‘Islamopolis’
Authors: Kolluoglu Poyraz
Published: January 2025

A colossal mosque, recently built by the current Islamic conservative government, now threateningly looms over Taksim Square where the memories of the Gezi Park protests silently mingle with the spirits of the Armenian cemetery lying beneath. The recent transformation of Istanbul’s historically most contested urban space, once recognized as Christian Pera, symbolically and also very intensely mirrors the latest backlash unleashed by ‘Islamopolis’ against the Ottoman cosmopolitanism and Turkish secularism, which are respectively framed as ‘urban affects’ in this article. Viewing the recent affective impact of Islamopolis as a scholarly invitation, I intend to revisit the urban origins of Istanbul’s Occupy encampment through the lenses of intersectional methodologies approaches and bourgeoning affect literature in urban studies.
Study of proliferative activity and gene expression (col1a1, mmp1a, mmp1b, mmp3, vcan, eln) in fibroblasts after exposure to collagen preparations
Authors: Morzhanaeva M , Svechnikova E , Babin V , Starkina O
Published: January 2025

The aim of the study was to evaluate the viability and proliferative activity of fibroblasts, as well as gene expression (collagen type 1 (COL1), elastin (ELN), matrix metalproteinase type 1 (MMP1), matrix metalproteinase type 3 (MMP3) and versican (VCAN )) after exposure to six different collagen preparations - dermal fillers.
Materials and methods. The standard MTT test was used to measure cell viability, proliferation and cytotoxicity. Gene expression was measured using real-time reverse transcription polymerase chain reaction (RT-rtPCR).
Results. The results obtained showed that the effectiveness of the studied drugs does not depend on the concentration of collagen in the final solution. When performing the MTT test, the greatest proliferative activity was observed for fibroblasts incubated with the Collost micro drug. For the Linerase drug, after 48 hours, a higher expression of collagen was observed compared to other drugs. It should be noted that there was no expression of the mmp1 gene after 24 hours in all samples except those treated with Collapro30+ and Collapro55+.
Based on the results of pairwise comparison, no significant differences between groups in MMP3 gene expression (24 hours and 48 hours after incubation) were revealed. Also, in samples treated with Collapro30+, Collapro45+ and Collapro55+, versican is expressed at a higher level on the first day of the study. In turn, on the second day, versican is expressed at a higher level in the Collapro45+ and Linerase preparations.
A comparative study of clinical and laboratory features of COVID-19 in children aged 0-14 years old
Authors: Pavlova M , Tomov T , Velikov P , Getsova J , Yordanova R , Kapintseva N , Popov M , Akcentieva Y , Velinova A , Ivanov I , Tolchkov V , Korsun N , Velev V
Published: January 2025

Coronavirus Disease 2019 (COVID-19) was a pandemic that emerged in early 2019, caused by the SARS-CoV-2 virus. Children accounted for a small proportion of the total number of patients with COVID-19. We studied 110 children between the ages of 0 and 14 who were treated in three hospitals in Bulgaria. The children were divided into three groups: those treated as outpatients only, those admitted to standard COVID-19 wards, and those admitted to intensive care units. The most common symptoms were fever, cough, sore throat, nasal congestion, and, less commonly, diarrhea, vomiting, abdominal pain, rapid breathing, tachycardia, and rarely the development of multisystem inflammation syndrome in children.. Older children, mostly with catarrhal symptoms, were treated on an outpatient basis, while younger children were hospitalized, especially those with fever, respiratory disorders, and laboratory evidence of inflammation. Children with multisystem inflammatory syndrome (MIS-C) or respiratory failure were treated in intensive care units. Obesity and neurological diseases are the main factors leading to a more severe disease course during COVID-19 infection.
Comparative study of organic co-solvents on micellar and surface behavior of ionic surfactants: effects of DMSO, acetonitrile, and 1-propanol
Authors: Shah Sujit Kumar , Giri Afshana , Adhikari Sarupa , Bhattarai Ajaya
Published: January 2025

This study investigates the effects of 10 % v/v dimethyl sulfoxide (DMSO), acetonitrile (ACN), and 1-propanol (1-PrOH) on the micellar and surface behavior of three ionic surfactants: sodiumdodecyl sulfate (SDS), dodecyltrimethylammonium bromide (DTAB), and cetylpyridinium chloride (CPC). The addition of co-solvents increased the critical micelle concentration (CMC), with 1-PrOH causing the largest increase due to its strong disruption of the hydrogen bonding network of water. Surface tension measurements revealed a decreased surface excess concentration (Γ
max) indicating reduced surface adsorption. The minimum area per molecule (A
min) increased with organic solvents, particularly in 1-PrOH-water mixtures, reflecting less efficient packing of the surfactant molecules at the surface. The packing parameter (P) decreased in mixed solvents, especially with 1-PrOH, suggesting a shift from spherical to elongated micellar structures. Aggregation numbers (N

agg
) were lower in mixed solvent systems, indicating smaller and less stable micelles. The free energy of adsorption (

∆

G

a
d
s

o

${\increment}{G}_{ads}^{o}$

) became less negative, indicating reduced spontaneity for micelle formation and adsorption, with the strongest impact seen in 1-PrOH. The overall trend of solvent effects was 1-PrOH > ACN > DMSO, highlighting the role of solvent polarity and amphiphilicity in altering surfactant behavior. These results provide valuable insights for the optimization of surfactant-based formulations.
Histone Methyltransferase G9a in Primary Sensory Neurons Promotes Inflammatory Pain and Transcription ofTrpa1andTrpv1via Bivalent Histone Modifications
Authors: Ghosh Krishna , Huang (黄玉莹) Yuying , Jin (金道忠) Daozhong , Chen (陈少瑞) Shao-Rui , Pan (潘惠麟) Hui-Lin
Published: January 2025

Transient receptor potential ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1) channels are crucial for detecting and transmitting nociceptive stimuli. Inflammatory pain is associated with sustained increases in TRPA1 and TRPV1 expression in primary sensory neurons. However, the epigenetic mechanisms driving this upregulation remain unknown. G9a (encoded byEhmt2) catalyzes H3K9me2 and generally represses gene transcription. In this study, we found that intrathecal administration of UNC0638, a specific G9a inhibitor, or G9a-specific siRNA, substantially reduced complete Freund's adjuvant (CFA)-induced pain hypersensitivity. Remarkably, CFA treatment did not induce persistent pain hypersensitivity in male and female mice with conditionalEhmt2knock-out in dorsal root ganglion (DRG) neurons. RNA sequencing and quantitative PCR analyses showed that CFA treatment caused a sustained increase in mRNA levels ofTrpa1andTrpv1in the DRG.Ehmt2knock-out in DRG neurons elevated baselineTrpa1andTrpv1mRNA levels but notably reversed CFA-induced increases in their expression. Chromatin immunoprecipitation revealed that CFA treatment reduced G9a and H3K9me2 levels while increasing H3K9ac and H3K4me3—activating histone marks—atTrpa1andTrpv1promoters in the DRG. Strikingly, conditionalEhmt2knock-out in DRG neurons not only diminished H3K9me2 but also reversed CFA-induced increases in H3K9ac and H3K4me3 atTrpa1andTrpv1promoters. Our findings suggest that G9a in primary sensory neurons constitutively repressesTrpa1andTrpv1transcription under normal conditions but paradoxically enhances their transcription during tissue inflammation. This latter action accounts for inflammation-induced TRPA1 and TRPV1 upregulation in the DRG. Thus, G9a could be targeted for alleviating persistent inflammatory pain.
Anogenital Findings in Confirmed Victims of Child Sexual Abuse Materials
Authors: Dai Thanh T. , Spiller Lora R. , Kellogg Nancy D. , Gelfond Jonathan
Published: January 2025

OBJECTIVE

The purpose of this study is to describe the medical evaluation including history, physical examination, and diagnostic testing results in children/adolescents who are confirmed subjects of child sexual abuse materials (CSAMs) and to compare these findings with age-matched controls who are suspected victims of sexual abuse without CSAMs.

METHODS

This retrospective case-control study examined anogenital findings and disclosure patterns in children who were aged no more than 17 years, who were evaluated for sexual abuse/assault at an urban children’s hospital, and who had additional history of being photographed and/or videotaped while performing sexual acts. Two control patients per study patient were matched by age (± 6 months), gender, acute vs nonacute examination, and type of sexual contact. Photo documentation of all anogenital examinations was reviewed by 2 child abuse pediatricians blinded to the clinical history.

RESULTS

There were 22 cases and 44 controls. Girls comprised 91% (60/66) of the patients. Fourteen cases (14/22; 64%) disclosed details of sexual abuse. Eight cases (36%) did not make a disclosure of sexual abuse; 4 were preverbal. Although half of the cases (12/22; 55%) were evaluated within 120 hours of the most recent sexual abuse contact, only 1 had an abnormal anogenital examination. There were no significant differences in examination findings or diagnostic tests when cases were compared with controls, but more than one-third of cases were preverbal or denied abuse.

CONCLUSION

Children with objective evidence of sexual abuse via CSAMs were unlikely to have examination findings of trauma and were frequently unable/unwilling to fully disclose their abuse.
Una aproximación hermenéutica de la evaluación educativa inclusiva: Certezas e incertidumbre
Authors: Esquea Gamero Osmeris Patricia
Published: January 2025

La inclusión educativa formulada como una de las metas de la agenda mundial, marca un giro a la verdadera naturaleza de la educación. Se destaca el avance significativo en adaptaciones curriculares y didácticas, pero en lo referido a la evaluación hay muchas brechas por superar. Este es el foco de atención de las reflexiones que se presentan, que, desde un enfoque hermenéutico reflexivo, a través de la aplicación de técnicas de revisión de literatura académica, documentos orientadores y normatividad, permite sumergirse en los significados y sentidos del objeto de estudio para consolidar así principios de comprensión. Todo este recorrido consolida un andamiaje sobre el cual se estructuran las reflexiones, orientadas a develar los avances y desafíos de la evaluación en el marco de la educación inclusiva. Para tal fin, se desarrolla un proceso de revisión, análisis e interpretación de los aportes teóricos y prácticos en relación con el objeto de estudio. De esta manera, se establece una ruta que inicia con el preludio centrado en los aportes teóricos, para luego revisar la integración de la teoría a las orientaciones hechas por las autoridades educativas y así presentar las certezas e incertidumbres de la evaluación inclusiva.
Pensamiento computacional en matemáticas con Code.org
Authors: Valbuena Sonia , Elías L. Willis , Berrio V. Jesús
Published: January 2025

El pensamiento computacional entendido como un proceso de pensamiento que envuelve formular un problema y sus soluciones de manera que estas son representadas y desarrolladas por un agente de procesamiento de información. Desde esta perspectiva, la investigación aquí presentada tuvo como objetivo desarrollar pensamiento matemático con apoyo del pensamiento computacional. El trabajo fue desarrollado durante la electiva de matemáticas bajo un enfoque cualitativo con una metodología por fases, la muestra objeto de estudio fueron estudiantes de media de una institución educativa trilingüe del caribe colombiano. La propuesta de trabajo utilizó code.org y desde una perspectiva innovadora asumió diseñar y aplicar una estrategia de enseñanza de las matemáticas, destacando la importancia del pensamiento computacional como mediador, las habilidades que desarrolla y los estrechos vínculos con el pensamiento matemático. Los resultados revelaron un notable aumento en la capacidad de los estudiantes para abordar desafíos matemáticos mediante la aplicación de principios computacionales. Se observó una mejora significativa en la resolución de problemas, la creatividad y la comprensión de conceptos matemáticos, además de un aumento en la motivación de los estudiantes. Se concluye que la integración de la programación puede hacer que las matemáticas sean más accesibles y atractivas para su aprendizaje.
Principles of Construction of Autodyne Interferometers and the Possibility of their Application in Optical Instrumentation Sy
Authors:   Ural Federal University named after first President of Russia B.N. Yeltsin, Ignatkov K. A. , Iskachev S. A. ,   JSC «Production Association «Ural Optical and Mechanical Plant named after E. S. Yalamov», Luchinin A. S. ,   Ural Federal University named after first President of Russia B.N. Yeltsin, Malygin I. V. ,   Ural Federal University named after first President of Russia B.N. Yeltsin, Noskov V. Ya. ,   Ural Federal University named after first President of Russia B.N. Yeltsin, Povetyev V. V. ,   JSC «Production Association «Ural Optical and Mechanical Plant named after E. S. Yalamov»
Published: January 2025

An overview of the principles of construction of autodyne interferometers and the possibilities of their application in optical instrumentation systems and devices is presented. At the same time, the current state of the theory of autodyne interferometers is analysed, the basic equations describing the formation of signals are given and the features of the autodyne characteristics at different levels of reflected radiation characterised by the feedback parameter are considered. Examples of the implementation of autodyne interferometers and the results of their use in metrology are presented. The prospects of using autodyne interferometers in optical instrumentation systems and devices are noted.
Assessing the Impact of Land Degradation on Agricultural Output Using a Stochastic Frontier Production Function
Authors:   RANEPA, Strokov A. S.
Published: January 2025

Land degradation is a widely discussed and pressing global issue, as highlighted in the UN Sustainable Development Goals (SDGs). Understanding the extent of land degradation and its impact on agriculture requires precise research and an interdisciplinary approach due to the complexity of factors and indicators that characterize the issue. This paper focuses on one of Russia’s key agricultural regions, Samara Oblast, to examine how land degradation of agricultural soils affects crop production at the farm level. The dataset used in the study includes farm inputs (costs, land, and labour) and land quality variables, such as organic content (humus), levels of land degradation and soil erosion, as well as climate indicators, at the municipal level. To analyse the relationship between land degradation and agricultural output, the stochastic frontier analysis (SFA) was employed. This method not only estimates the parameters of a classic production function but also accounts for errors in the model by evaluating parameters related to risk and technical inefficiency. The results indicate that the proportion of degraded land in a district of the given region moderately reduces the maximum potential for crop production. In contrast, most inputs—such as production costs, cropland area, and labour—contribute positively to output. The study suggests that both the method and the estimates could be refined if data on land degradation, alongside other economic and environmental indicators, were collected and published annually.
Building a Rating of Russian Regions According to their Level of Financial Market Development
Authors:   Southern Main Branch of the Central Bank of the Russian Federation, Kirichenko P. S. , Arzhenovskiy S. V. ,   Southern Main Branch of the Central Bank of the Russian Federation
Published: January 2025

The use of indicators characterizing the regional level of its functioning is relevant for monitoring the development of the financial market. The purpose of the article is to develop an approach to build a rating of Russian regions according their level of the financial market development. The authors’ methodology includes integral indicators calculating, which characterize the development of the financial market in terms of the territorial entities using the method of principal components. As a result, we have built a composite index, and on its basis a rating of Russian regions is compiled. The components of the composite index are subindexes, calculated using the method of principal components for each of the five market sectors: banking, insurance, microfinance, non-state pension funds and stock market. On the one hand, this approach allows to aggregate heterogeneous initial indicators of financial market sectors. On the other hand, it helps making a comparative analysis of regions in intersectoral terms. The research is based on the statistical data of Rosstat, the Bank of Russia and the Federal Tax Service for 2020–2022. The authors conclude that the constructed rating allows to track changes in the positions of the constituent entities of regions on the financial market and to detail the development areas of its specific sectors. For example, in 2022, the rating leaders were Moscow (1st place), Tyumen (2nd place) and Novosibirsk Oblasts (3rd place). In general, over 2020–2022, the Kamchatka Kray (banking sector), Chukotka Autonomous Okrug (banking sector), Kostroma Oblast (banking and stock sectors) significantly improved their position in the rating. Growth zones for the Tver Oblast are the insurance, microfinance and stock sectors, for the Bryansk and Volgograd Oblasts the insurance and microfinance sectors. The approach proposed by the authors allows expanding the composition of the index components, which characterizes a high potential of its application in solving the problems of the financial market assessment.
Los emigrantes asturianos y la modernización de los sistemas de abastecimiento de agua (1880-1936)
Authors: Prieto Fernández del Viso José Manuel
Published: January 2025

In the inter-century period, Asturian emigrants began to finance dozens of infrastructures that allowed to improve the water supply situation in the rural areas of the region, and even in some cases to implant the modern water supply system. The aim of this work, after briefly analysing the state of the water supply in Asturias at that time and reviewing the different studies on the subject, is precisely to evaluate those actions of the Americans, seeking to understand their reasons; to review the ways in which they financed the different equipments; and to try to establish a quantification as accurate as possible of the infrastructures built, also seeking to assess the impact that this set of investments intended for modernising the water supply systems had on the daily lives of thousands of Asturian people
Features of the cytokine profile of the cervical mucosa in women with co-infection of HIV and HPV
Authors: Vyalykh Ivan V.
Published: January 2025

The high-risk human papillomavirus (HPV) is considered the main etiological agent of cervical cancer. Among HIV-infected women, human papillomavirus infection leads to the development of cervical intraepithelial neoplasia and cervical cancer 3-4 times more often than in HIV-negative women, despite effective combination antiretroviral therapy. The host immune response is critical in determining the course of infection, and cytokines and chemokines play important roles in protection against HPV by influencing viral replication and modulation of the Th1 or Th2 immune response. The purpose of this work is to analyze the available research data on the concentration of cytokines in the mucous membrane of the cervix and their effect on the development of human papillomavirus infection in HIV-infected women. Methods. For a systematic review, we analyzed published data from studies that assessed the levels of cytokines and chemokines in women living with HIV of reproductive age 18 years and older. The analysis included cohort, cross-sectional and case-control studies. Results. An analysis of data on studies of the level of cytokines and chemokines in samples of biopsy material and scrapings of the cervix and cervical canal in women with co-infection with HIV and HPV is presented. Data on the cytokine profiles of interferon gamma (IFN-γ), interleukin-10 (IL-10), tumor necrosis factor (TNF), interleukin-6 (IL-6) and macrophage inflammatory protein (MIP) are presented. Conclusion. Knowledge of immunological mechanisms and their influence on HPV infection in HIV-positive women can help in understanding the natural history of infection, improving diagnosis and developing effective methods of prevention and treatment to prevent progression of the disease. Due to the increased risk of HPV infection and the subsequent development of cervical intraepithelial disorders and cervical cancer in HIV-infected women, the possibility of strengthening preventive vaccination measures against HPV should be considered.
Syncretic constructions with the pronominal adverb «как» in the Russian language: determination of grammatical status
Authors: Sineleva A. V. , Zaitseva A. S.
Published: January 2025

The article is devoted to the study of the syncretic constructions with a pronominal adverb «как» in the Russian language. These constructions are analyzed in the lexico-grammatical aspect in comparison with introductory sentences and subordinate clauses. The material for the study consists of the texts of printed and electronic media included in the National Corpus of the Russian Language (NCRL). During the study, based on a diachronic approach, the classifications of constructions with a pronominal adverb «как» presented in the authoritative publications of the Russian language grammar are analyzed. As a result, within the framework of structural-semantic classification, a conclusion is made about the possibility of classifying constructions with an adverb «как» a subordinate clause, which makes it possible to minimize transitional cases while differentiating certain syntactic categories.
Medical terminology of patients’ medical cases: structural and semantic analysis
Authors: Andreeva M. I. , Shaekhova R. R.
Published: January 2025

The research focuses on the pivotal issue of human-related nominations of medical terminology. The scrutiny is given to the terminology of patients’ medical cases and complete management. The work attempts to fill in the research niche of structural, semantic analysis and specifics of interlinguistic equivalents of English and Russian medical terminology of patient cases. The nominations of human body, conditions, triggers and medical manipulations are studied. The research material, followed methods and approaches contribute to the research relevance implemented within human-oriented paradigm. The study aims at clarifying and specifying the semantic and structural features of medical terms elicited from the subcorpora of patient cases presented in the ‘House M.D.’ TV series, compiled by the authors. The aim is achieved through the study of semantic components, contextual features, lexical valency and derivational features of 168 terms. The corpora-based approach combined with text proces sing tools and techniques used by the authors make the research novel. Moreover, the developed algorithm provides a solid base for further investigations alike. The research was implemented in four stages. The word frequency analysis of the words in the compiled corpora showed the prevalence of medical terms. The number of terminological word combinations equals to one-word terms. Among the former word combinations with prepositions are not frequent. The latter exhibit clear derivational patterns with a marked set of word formation suffixes. The distribution of the terms into semantic groups revealed the prevalence of the semes ‘diagnosis’, ‘symptoms’ and ‘pathology’. The need for transliteration of English-Russian equivalents of medical terms arises due to the Latin origin of the most part of the terms which may be regarded as international medical vocabulary.
«Have fear of God! I am suffering»: mentally ill everyday life of the era of A.F. Kerensky. Anthropology of emotions
Authors: Kobozeva Z. M. , Kabytov P. S.
Published: January 2025

The article analyzes the emotional community of the Russian public, agitated by the pre-revolutionary sentiments, whose reaction was expressed in letters from citizens to A.F. Kerensky in 1917. The letters do not carry political ideas. They are all focused on the immediate emotions of the senders. During the formation of the file preserved in the GARF funds, all letters from citizens were divided into 2 groups. Letters from crazy people and letters from ordinary citizens. It is difficult to understand how and by whom this watershed was drawn between the mental norm and deviation from the norm. Therefore, this incident draws us not only to the problem of the «history of emotions», but also to the issue actualized in the works of M. Foucault: society and madness. Which was perceived as madness in one era or another. How clearly was insanity diagnosed in Russian society in 1917, as a disease, if any radical socio–political change forces people to live in a situation of a kind of insanity, when the norms of the old collapse and completely new texts of behavior and circumstances of life are created. How can a layman not go crazy? Or the letters to A.F. Kerensky are just a manifestation of the so-called «culture of the political», by which the «new social history» understands the daily political activity of the masses. This article actualizes the approach coming from the «history of emotions» to the analysis of the incident – letters of citizens to A.F. Kerensky.
Understanding Resilience in the Context of Sustainable HRM and the Human–Nature Relationship
Authors: Niemi Sari , Pietiläinen Ville , Suhonen Marjo
Published: January 2025

This study proposes that the deepening ecological crisis requires novel frameworks of resilience at work so that it considers the human–nature relationship. Increased sustainability reporting provides a platform to disclose how organizations practice sustainable HRM as a part of the SDGs. The research questions are: How are resilience approaches illustrated in sustainable HRM reporting? What argumentation is used for resilience approaches? What HRM practices are associated with different resilience approaches? The sustainability reports of 10 well-known Finnish organizations were studied using reflexive thematic analysis. The results identified that resilience is well addressed in the organizations’ SHRM at the individual and human interaction levels. However, the ecocrisis is not the challenge for which organizations are preparing SHRM in practice. Despite the good intentions of SHRM, the pursuit of resilience can lead to contradictions in terms of socioecological resilience. More conceptual guidelines are needed to emphasize the connection with the human–nature relationship.
Studies on the Efficacy of Phage in Controlling Staphylococcus aureus Biofilm Phenotype Associated with Mastitis
Authors: Sandhu Jagnoor , Chandra Mudit , Kaur Gurpreet , Narang Deepti , Arora A.K.
Published: January 2025

Background: The study aimed to investigate the effectiveness of phage in controlling Staphylococcus aureus (S. aureus) biofilm phenotypes associated with mastitis. Methods: The study was carried out with qualitative assessment and quantitative assessment of biofilm producing ability of the S. aureus isolates by using Congo Red Agar Assay (CRA) and Modified Congo Red Agar Assay (MCRA) respectively. The biofilm formed was treated with phage to evaluate its efficacy in removing the biofilm. Result: A total of 18 isolates of S. aureus (S1-S18) were isolated and identified from mastitis cases. Among the 18 isolates of S. aureus, many exhibited strong biofilm producing capabilities (22.22% on CRA and 33.33% on MCRA). Biofilm formed was treated with phage to evaluate its efficacy in removing the biofilm and it was observed that exposure to high phage titre (5x107 PFU/ml) over 24 h significantly reduced biofilm biomass (83.14%) whereas low phage titre (1.5x107 PFU/ml) exhibited significant yet less effectiveness in controlling biofilm. The phage action on biofilm resulted in a decline in bacteria (19.99%) while increasing phage (11.50%). These findings demonstrated the potential of high-concentration phage in treating biofilm phenotype.
Recent advances in functionalized separators for shuttle-free and dendrite-free lithium/sodium-sulfur batteries
Authors: Wu Yu , Huang Jinri , Zhang Ziheng , Chen Daiqian , Yu Hesheng , Ma Fei , Zhang Xiaojuan , Chen Yuanfu
Published: January 2025

With the extremely high theoretical energy densities, secondary batteries including lithium-sulfur (Li-S) and sodium-sulfur (Na-S) batteries are anticipated to become the leading candidates among metal-sulfur batteries. However, the practical energy density and storage efficiency of Li/Na-sulfur batteries are significantly hindered by several issues: the low conductivity of sulfur cathodes, substantial volume changes during charge and discharge cycles, the shuttle effect caused by metal polysulfides, and uncontrollable dendrite formation on the reactive alkali metal anodes, which also heighten safety concerns. Constructing functionalized separators is considered one of the most promising strategies to overcome these challenges and enhance the performance of Li/Na-sulfur batteries. Functionalized separators offer numerous advantages such as enhanced mechanical stability, bifunctionality in suppressing the shuttle effect and dendrite growth, and minimal impact on battery energy density and volume. However, comprehensive reviews of Li/Na-sulfur functionalized separators are relatively fewer, while the related research has increased significantly. In this context, it is crucial to provide a comprehensive review of recent advances in functionalized separators for Li/Na-sulfur batteries. First, this review offers an in-depth analysis of the current issues faced by Li/Na-sulfur batteries and summarizes the requirements of separators for improving Li/Na-sulfur batteries. Subsequently, a detailed discussion is presented about the performances and applications especially in shuttle effect inhibition and dendrite growth suppression of functionalized separators in Li-S and Na-S batteries. Finally, the review addresses the challenges and potential future research directions for functionalized separators in Li/Na-sulfur batteries.
A Comprehensive Review of Sensor Technologies and Signal Processing Solutions for Low-Power IoT Systems with Mini Computing Devices
Authors: Gazis Alexandros , Papadongonas Ioannis , Andriopoulos Athanasios , Zioudas Constantinos , Vavouras Theodoros
Published: January 2025

Τhis paper provides a comprehensive overview of sensors commonly used in low-cost, low-power systems, focusing on key concepts such as IoT, Big Data, and smart sensor technologies. It defines the evolving roles of sensors, emphasizing their characteristics, technological advancements, and the transition toward 'smart sensors' with integrated processing capabilities. The article also explores the increasing significance of mini computing devices in educational environments. These devices offer cost-effective and energy-efficient solutions for system monitoring, prototype validation, and real-world application development. By interfacing with wireless sensor networks and IoT systems, mini-computers enable students and researchers to design, test, and deploy sensor-based systems with minimal resource requirements. Furthermore, the paper discusses the use of signal processing techniques to enhance data acquisition and measurement accuracy, making these systems more reliable and suitable for various educational and research applications. This research aims to equip future engineers with the knowledge and tools to integrate cutting-edge sensor networks, IoT, and Big Data technologies into scalable, real-world solutions.
Effects of a Tele-Prehabilitation Program with Indirect Electrostimulation Compared to Home-Based Exercise in Patients eligibles for Lower Limb Arthroplasty: A Randomized Controlled Trial
Authors: Patanè Pamela , Carnevale Pellino Vittoria , Febbi Massimiliano , Cavallo Caterina , Gervasoni Fabrizio , Gatti Alessandro , Caldarella Emanuele , de Caro Francesca , Vandoni Matteo , Manzoni Federica , Marin Luca
Published: January 2025

Background/Objectives: Hip and knee arthroplasty relieves pain, restores mobility, and improves function in severe joint damage, though pain and strength loss may persist post-surgery. Better pre-surgery function and activity predict improved arthroplasty outcomes. Prehabilitation programs enhance functional abilities, reducing hospitalization duration, and lowering peri-surgery complication risks. This study aims to evaluate the efficacy of four weeks of different modalities of tele-home-prehabilitation programs on perceived pain and functional capacity in patients who are eligible for hip or knee arthroplasty. Methods: Forty-four patients (aged 65-80 years) eligible for elective lower limb arthroplasty were enrolled in the present randomized controlled trial study. Participants were randomly assigned to the Electrostimulation Group (EG) or the Home-based exercise Group (HG). The EG performed teleprehabilitation program using Indirect neuromuscular electrostimulation therapy, while the HG performed home-based exercise supervised by sports specialist. Functional capacity was assessed with the Timed Up and Go test, the 30-Second Chair Stand test (30CST) and the 6-minute walking test (6MWT). Quality of life was assessed with the Oxford Hip Score (OHS) or Oxford Knee Score (OKS), depending on the participants’ surgery. The Technology Acceptance Model (TAM) questionnaire was completed by the EG group after the intervention. Results: No significant differences were found among groups in the 30CST and TUG tests. The analyses revealed significant differences for the Oxford Questionnaires and 6MWT. Conclusions: Our study highlights the potential of teleprehabilitation using indirect neuromuscular electrostimulation to improve walking autonomy and quality of life of individuals who are candidates for lower limb arthroplasty.
A Combined Thermodynamic and Computational Study of Alkaline Earth Metal Cations Complexation by a Fluorescent calix[4]arene Receptor
Authors: Usenik Andrea , Modrušan Matija , Leko Katarina , Borovec Jakov , Marinac Sven , Hok Lucija , Cindro Nikola , Vianello Robert , Horvat Gordan , Požar Josip , Hrenar Tomica , Tomišić Vladislav
Published: January 2025

Complexation of alkaline earth metal cations with fluorescent tertiary-amide lower-rim calix[4]arene derivative bearing two phenanthridine moieties was studied experimentally (UV spectrophotometry, fluorimetry, isothermal microcalorimetry, NMR spectroscopy) and computationally (classical molecular dynamics and DFT calculations) at 25 °C. The complexation reactions were studied in acetonitrile, methanol, and ethanol, whereby the solvent effect on cation-binding processes was particularly addressed. The complex stability constants and standard reaction thermodynamic quantities (Gibbs energies, enthalpies, and entropies) were determined. The receptor exhibited particularly high affinity towards alkaline earth metal cations in acetonitrile, with peak affinity for Ca2+. The stability of all complexes was significantly lower in ethanol and methanol, where the most stable complex was formed with Sr2+. The decrease in cation-binding abilities was a consequence of the differences in solvation of the reactants and products of the complexation reactions (involving inclusion of the solvent molecule in the calixarene cone), cation charge density, as well as the cation-ligand binding site compatibility. The reactions were enthalpically controlled in acetonitrile, whereas in methanol and ethanol the binding processes were endothermic, and thus entropy driven. The results of 1H NMR measurements, MD simulations, and DFT calculations provided an insight into the structure of the complexes and the corresponding adducts with solvent molecules, as well as on the structural aspects behind the differences in complexation thermodynamics. Due to the significant increase of its fluorescence upon cation binding, the studied calixarene derivative was proven to be a promising luminescent sensor for alkaline earth metal cations.