bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Interstitial Oxygen in Perovskite‐Related Sr6‐2xNb2+2xO11+3x.
Authors: Li Man‐Rong , Hong Seung‐Tae
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Al—B—Nb—Ti System. Part 2. Thermodynamic Description of the Constituent Ternary System B—Nb—Ti.
Authors: Witusiewicz V. T. , Bondar A. A. , Hecht U. , Rex S. , Velikanova T. Ya.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Crystal and Band Structures, and Optical Characterizations of Sodium Rare Earth Phosphates NaLnP2O7 and NaLn(PO3)4 (Ln: Ce, Eu).
Authors: Zhu Jing , Cheng Wen‐Dan , Wu Dong‐Sheng , Zhang Hao , Gong Ya‐Jing , Tong Hua‐Nan , Zhao Dan
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Nitrido‐Centered Uranium Azido Cluster Obtained from a Uranium Azide.
Authors: Nocton Gregory , Pecaut Jacques , Mazzanti Marinella
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemodivergence in Enantioselective Desymmetrization of Diazabicycles: Ring‐Opening versus Reductive Arylation.
Authors: Menard Frederic , Lautens Mark
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral Amine‐Thioureas Bearing Multiple Hydrogen Bonding Donors: Highly Efficient Organocatalysts for Asymmetric Michael Addition of Acetylacetone to Nitroolefins.
Authors: Wang Chun‐Jiang , Zhang Zhi‐Hai , Dong Xiu‐Qin , Wu Xiao‐Jun
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enamide Synthesis by Copper‐Catalyzed Cross‐Coupling of Amides and Potassium Alkenyltrifluoroborate Salts.
Authors: Bolshan Yuri , Batey Robert A.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ruthenium‐Catalyzed Vinylic Substitution Reactions with Nucleophiles via Butatrienylidene Intermediates.
Authors: Yamauchi Yoshihiro , Yuki Masahiro , Tanabe Yoshiaki , Miyake Yoshihiro , Inada Youichi , Uemura Sakae , Nishibayashi Yoshiaki
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enzyme‐Like Chemoselective Acylation of Alcohols in the Presence of Amines Catalyzed by a Tetranuclear Zinc Cluster.
Authors: Ohshima Takashi , Iwasaki Takanori , Maegawa Yusuke , Yoshiyama Asako , Mashima Kazushi
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rhodium‐Catalyzed Hydroarylation and Hydroalkenylation of Alkynes Using Organo[2‐(hydroxymethyl)phenyl]dimethylsilanes.
Authors: Nakao Yoshiaki , Takeda Masahide , Chen Jinshui , Hiyama Tamejiro
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rh(III)‐ and Ir(III)‐Catalyzed Asymmetric Transfer Hydrogenation of Ketones in Water.
Authors: Wu Xiaofeng , Li Xiaohong , Zanotti‐Gerosa Antonio , Pettman Allan , Liu Jianke , Mills Allan James , Xiao Jianliang
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Carbonylation of Aryl Tosylates and Mesylates.
Authors: Munday Rachel H. , Martinelli Joseph R. , Buchwald Stephen L.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sustainable Suzuki—Miyaura Reaction Catalyzed by Pd(OAc)2 Immobilized on Reversed‐Phase Alumina.
Authors: Hagiwara Hisahiro , Ko Keon Hyeok , Hoshi Takashi , Suzuki Toshio
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Step Synthesis of Polysubstituted Benzene Derivatives by Multicomponent Cyclization of α‐Bromoacetate, Malononitrile and Aromatic Aldehydes.
Authors: Yan Chao Guo , Song Xiao Kai , Wang Qi Fang , Sun Jing , Siemeling Ulrich , Bruhn Clemens
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ring Selectivity: Successive Ring Expansion of Two Benzocyclobutenes for Divergent Access to Angular and Linear Benzanthraquinones.
Authors: Suzuki Takeaki , Hamura Toshiyuki , Suzuki Keisuke
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gold(I)‐Catalyzed Intramolecular Hydroarylation of Allenes.
Authors: Tarselli Michael A. , Gagne Michel R.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Stereoselective Synthesis of Substituted γ‐Lactams from Acylsilanes.
Authors: Lettan Robert B. II , Woodward Chase C. , Scheidt Karl A.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of 2,6‐Dioxo‐1,2,3,4,5,6‐hexahydroindoles Based on the Synthesis and Reactions of (2,4‐Dioxocyclohex‐1‐yl)acetic Acid Derivatives.
Authors: Juma Benard , Adeel Muhammad , Villinger Alexander , Langer Peter
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Promoted Oxidation of 1,3,5‐Trisubstituted 4,5‐Dihydro‐1H‐pyrazoles by in situ Generation of NO+ and NO2+ Respectively from Sodium Nitrite and Sodium Nitrate in Acetic Acid.
Authors: Azarifar Davood , Maleki Behrooz , Sahraei Mahta
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Amination of Homoenolates Catalyzed by N‐Heterocyclic Carbenes.
Authors: Chan Audrey , Scheidt Karl A.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient and One‐Pot Synthesis of 2,4,5‐Trisubstituted and 1,2,4,5‐Tetrasubstituted Imidazoles Catalyzed by InCl3×3H2O.
Authors: Das Sharma Saikat , Hazarika Parasa , Konwar Dilip
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Facile Synthesis of 5(6)‐(Chloromethyl)benzimidazoles: Replacement of a Sulfonic Acid Functionality by Chlorine.
Authors: Pete Bela , Szokol Balint , Toeke Laszlo
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Simple and Efficient One‐Pot Synthesis of 3,4‐Dihydro‐2‐pyridones via Solid‐Supported Bi(III)nitrate‐Catalyzed Double Michael Addition—Azaannulation.
Authors: Singh Jagjeet , Koul Summon , Pannu Ajay P. S. , Sharma Rattan L. , Razdan Tej K.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Doebner Synthesis of 2‐Phenylquinoline‐4‐carboxylic Acids and Their Antiparasitic Activities.
Authors: Muscia Gisela C. , Carnevale Juan P. , Bollini Mariela , Asis Silvia E.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of a Novel Heterocycle: 1‐Substituted‐4‐arylazamethylene‐6‐arylpyrazolo[5,4‐d]‐1,3‐oxazine.
Authors: He Kunlun , Lv Houjun , Wang Junbo , Qiu Guofu , Hu Xianming
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rh‐Catalyzed Carbonyl Hydroacylation: An Enantioselective Approach to Lactones.
Authors: Shen Zengming , Khan Hasan A. , Dong Vy M.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Two New Cycloartane Saponins from the Roots of Astragalus membranaceus
Authors: Kim Ju Sun , Yean Min‐Hye , Lee Eun‐Ju , Jung Hye Sil , Lee Joo Young , Kim Yoon Jung , Kang Sam Sik
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Syntheses of Bistratamides J, E, and H from Two Types of ΔAla‐Containing Oligopeptides.
Authors: Suzuki Hiroyuki , Andoh Masanori , Yonezawa Yasuchika , Akai Shoji , Shin Chung‐gi , Sato Ken‐ichi
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of Novel Azo‐Morphine Derivatives for Possible Use in Abused Drugs Analysis.
Authors: Alnajjar Ahmed O. , El‐Zaria Mohamed E.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unsaturated Fluoro‐ketopyranosyl Nucleosides: Synthesis and Biological Evaluation of 3‐Fluoro‐4‐keto‐β‐D‐glucopyranosyl Derivatives of N4‐Benzoyl Cytosine and N6‐Benzoyl Adenine.
Authors: Manta Stella , Agelis George , Botic Tanja , Cencic Avrelija , Komiotis Dimitri
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Flexophore, a New Versatile 3D Pharmacophore Descriptor that Considers Molecular Flexibility.
Authors: von Korff Modest , Freyss Joel , Sander Thomas
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Exploiting Structure—Activity Relationships in Docking.
Authors: Sullivan David C. , Martin Eric J.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Docking Ligands into Flexible and Solvated Macromolecules. Part 2. Development and Application of FITTED 1.5 to the Virtual Screening of Potential HCV Polymerase Inhibitors.
Authors: Corbeil Christopher R. , Englebienne Pablo , Yannopoulos Constantin G. , Chan Laval , Das Sanjoy K. , Bilimoria Darius , L'Heureux Lucille , Moitessier Nicolas
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enhancement of Ordinal CoMFA by Ridge Logistic Partial Least Squares.
Authors: Ohgaru Takanori , Shimizu Ryo , Okamoto Kosuke , Kawashita Norihito , Kawase Masaya , Shirakuni Yuko , Nishikiori Rika , Takagi Tatsuya
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Nb—Ni—Ti (Niobium—Nickel—Titanium) System‐update
Authors: Gupta K. P.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Al—Nd—Ti (Aluminum—Neodymium—Titanium)
Authors: Raghavan V.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Development of a New Production Process for N‐Vinyl‐2‐pyrrolidone
Authors: Shimasaki Yuuji , Yano Hitoshi , Sugiura Hideto , Kambe Hideyuki
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic C—C, C—N, and C—O Ullmann‐Type Coupling Reactions: Copper Makes a Difference
Authors: Monnier Florian , Taillefer Marc
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aryl and 1,3‐Dioxoindanyl Derivatives of Azoles and Azines
Authors: Garnovskii A. D. , Sennikova E. V.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances in Enantioselective [2 + 2 + 2] Cycloaddition.
Authors: Shibata Takanori , Tsuchikama Kyoji
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral Memory: Induction, Amplification, and Switching in Porphyrin Assemblies
Authors: Rosaria Lauceri , D'Urso Alessandro , Mammana Angela , Purrello Roberto
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel RNA Synthetic Method with a 2′‐O‐(2‐Cyanoethoxymethyl) Protecting Group
Authors: Shiba Yoshinobu , Kitagawa Hidetoshi , Masutomi Yutaka , Ishiyama Kouichi , Ohgi Tadaaki , Yano Junichi
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 3′‐(Ureido)adenosine Derivatives and Their High Binding Affinity at the Mutant A3 Adenosine Receptor
Authors: Kim Ae Yil , Kim Hea Ok , Kim Myoung Jung , Chun Moon Woo , Lee Kang Man , Jacobson Kenneth A. , Jeong Lak Shin
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Molecular Modeling of the Biologically Active Alkaloids
Authors: Tareq Mahmud , Khan Hassan
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry and Biological Activity of Tetrahydrocannabinol and Its Derivatives
Authors: Flemming T. , Muntendam R. , Steup C. , Kayser Oliver
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polymer‐Induced Transient Pores in Lipid Membranes
Authors: Binder Wolfgang H.
Published: June 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The role of π‐acidic and π‐basic chiral stationary phases in the high‐performance liquid chromatographic enantioseparation of unusual β‐amino acids
Authors: Ilisz István , Berkecz Róbert , Forró Enikő , Fülöp Ferenc , Armstrong Daniel W. , Péter Antal
Published: June 2008

The application of 3,5‐dimethylphenyl‐carbamoylated‐β‐cyclodextrin (Cyclobond I 2000 DMP) and 2,6‐dinitro‐4‐trifluoromethylphenyl‐ether‐β‐cyclodextrin‐based (Cyclobond DNP) chiral stationary phases for the high‐performance liquid chromatographic enantioseparation of unusual β‐amino acids is reported. The investigated amino acids were saturated or unsaturated alicyclic β‐3‐homo‐amino acids and bicyclic β‐amino acids. Prior to chromatographic analyses, all amino acids were transformed to N‐3,5‐dinitrobenzoyl‐ or N‐3,5‐dimethylbenzoyl form to ensure a π‐acidic or π‐basic function and to enhance the π‐acidic‐π‐basic interactions between analytes and chiral selectors. Chromatographic results are given as retention, separation and resolution factors. The chromatographic conditions were varied to achieve optimal separation. The sequence of elution of the enantiomers was determined in some cases. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
Enantiomers of a nonylphenol isomer: Absolute configurations and estrogenic potencies
Authors: Zhang Haifeng , Oppel Iris M. , Spiteller Michael , Guenther Klaus , Boehmler Gabriele , Zuehlke Sebastian
Published: June 2008

Enantiomers of 4‐(1,1,2‐trimethylhexyl)phenol, a chiral isomer of the endocrine disrupting chemical nonylphenol, have been resolved and isolated by preparative chiral HPLC. The absolute configurations of the enantiomers were then determined by an X‐ray crystallographic study of the (−)‐camphanoyl derivative of the first eluted enantiomer NP35E1. The first enantiomer (NP35E1) and the second enantiomer (NP35E2) eluted were found to have the S and R absolute configurations, respectively. The estrogenic potencies of the S and R enantiomers were tested by the E‐screen assay. A slight difference was observed in the relative proliferative effect between the S enantiomer and R enantiomer in the E‐screen assay. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
Cellulose tris(3,5‐dimethylphenylcarbamate)‐based chiral stationary phases as effective tools for enantioselective HPLC separation of structurally different disubstituted binaphthyls
Authors: Loukotková Lucie , Rambousková Milena , Bosáková Zuzana , Tesařová Eva
Published: June 2008

Cellulose tris(3,5‐dimethylphenylcarbamate)‐based chiral stationary phases (CSPs) were used for a study of the HPLC retention and enantioseparation behavior of 2,2′‐disubstituted or 3,2,2′‐trisubstituted 1,1′‐binaphthyls and 8,3′‐disubstituted 1,2′‐binaphthyls. The effects of the mobile phase composition in normal‐ (NP) and reversed‐phase (RP) separation modes were investigated. The NP mobile phases contained n‐hexane and propane‐2‐ol at various volume ratios, the RP ones were obtained by mixing acetonitrile with water or a 20 mM phosphate buffer of pH 6.0 or 3.0. The RP separation mode has been found more suitable for enantioresolution of most of the analytes. The best enantioseparation of 2,2′‐diacetyl‐1,1′‐binaphthyl, 2‐hydroxy‐2′‐(phenylamino)‐1,1′‐binaphthyl‐3‐carboxylic acid and 2‐amino‐2′‐hydroxy‐1,1′‐binaphthyl‐3‐carboxylic acid was obtained in the mobile phase of ACN/20 mM phosphate buffer, pH 3.0, 40/60 (v/v), whereas N‐(2′‐hydroxy‐1,1′‐binaphthyl‐2‐yl)acetamide, N‐(3′‐methoxy‐1,2′‐binaphthyl‐8‐yl)acetamide, and N‐(3′‐hydroxy‐1,2′‐binaphthyl‐8‐yl)acetamide yielded better results in ACN/water at the same v/v ratio. The analyte–CSP interaction mechanism was found to be temperature independent but the enantioresolution improved at an elevated temperature. The mechanism of the enantioselective discrimination is discussed on the basis of the thermodynamic parameters obtained. Semi‐preparative separation conditions have been proposed for 2‐amino‐2′‐hydroxy‐1,1′‐binaphthyl‐3‐carboxylic acid, N‐(3′‐methoxy‐1,2′‐binaphthyl‐8‐yl)acetamide, and N‐(3′‐hydroxy‐1,2′‐binaphthyl‐8‐yl)acetamide. Chirality, 2008. © 2008 Wiley‐Liss, Inc.
Direct screening of chiral discrimination abilities of chiral hosts using mass spectrometry
Authors: Shizuma Motohiro , Adachi Hiroshi , Ono Daisuke , Sato Hirofumi , Nakamura Masaki
Published: June 2008

A simultaneous estimation of the chiral discrimination abilities of several chiral hosts was demonstrated on the basis of one mass spectrum. The chiral host mixture, including H1, H2, H3 ···, and Hm (m: number of hosts) was prepared by etherification of several chiral alcohols with bistosylate of diethylene glycol. An equimolar mixture of a deuterium‐labeled (S)‐ and unlabeled (R)‐enantiomer of an amino acid isopropyl ester hydrochloride (GS‐dn+Cl− and GR+Cl−, n: number of deuterium atoms) was added to the chiral host mixture, and the FAB mass spectrum was measured to evaluate the chiral discrimination ability of each host in the mixture without isolation. The chiral discrimination ability of each host toward the guest is represented by the relative peak intensity of the diastereomeric complex ion pair, I(Hm + GR(+/I(Hm + GS‐dn)+ (=IR/IS‐dn value). Several new hosts showed good chiral discrimination toward the guest. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
A rational approach to predict and modulate stereolability of chiral α substituted ketones
Authors: Cirilli Roberto , Costi Roberta , Di Santo Roberto , Gasparrini Francesco , La Torre Francesco , Pierini Marco , Siani Gabriella
Published: June 2008

An effective strategy to assess and modulate the stereolability of chiral α substituted ketones (CαSKs) is presented. The tendency of CαSKs to retain or change their configuration in water is analyzed as a function of thermodynamic proton‐release attitude of α asymmetric atoms inside the structures by linear Brønsted correlations. A molecular modeling procedure was developed to analyze and suggest chemical modifications of CαSKs in view to obtain the desired grade of stereochemical stability. The approach was employed to predict the tendency to enantiomerize in water of two ketones (1 and 2) endowed with inhibitory activity against monoamine oxidases (MAOs) and the results were confirmed by experimental kinetics measurements performed in organic medium. As a demonstration of practical potentialities of the approach, four new structures, conceived as simple chemical modifications of 1 and 2, were designed to improve/reduce the stereostability grade of the starting anti‐MAO ketones. The possibility to extend easily the procedure to other classes of CH acids appears of interest. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
Biphasic recognition chiral extraction: A novel method for separation of mandelic acid enantiomers
Authors: Tang Kewen , Yi Jianmin , Huang Kelong , Zhang Guoli
Published: June 2008

This article reports a new chiral separation method—biphasic recognition chiral extraction for the separation of mandelic acid enantiomers. Distribution behavior of mandelic acid enantiomers was studied in the extraction system with O,O′‐di‐benzoyl‐(2S,3S)‐4‐toluoyl‐tartaric acid (D‐(+)‐DTTA) in organic phase and β‐CD derivatives in aqueous phase, and the influence of the types and concentrations of extractants and pH on extraction efficiency was investigated. Hydroxypropyl‐β‐cyclodextrin (HP‐β‐CD), hydroxyethyl‐β‐cyclodextrin (HE‐β‐CD), and methyl‐β‐cyclodextrin (Me‐β‐CD) have stronger recognition abilities for S‐mandelic acid than those for R‐mandelic acid, among which HP‐β‐CD has the strongest ability. D‐(+)‐DTTA preferentially recognizes R‐mandelic acid. pH and the concentrations of extractants have great effects on chiral separation ability. A high enantioseparation efficiency with a maximum enantioselectivity of 1.527 is obtained at pH of 2.7 and the ratio of 2:1 of [D‐(+)‐DTTA] to [HP‐β‐CD]. The obtained results indicate that the biphasic recognition chiral extraction is of stronger chiral separation ability than the monophasic recognition chiral extraction. It may be very helpful to optimize the extraction systems and realize the large‐scale production of pure enantiomers. Chirality, 2009. © 2008 Wiley‐Liss, Inc.
Trans‐admittance control for eliminating the temperature effect of piezoelectric transformer in the CCFL backlight module
Authors: Lo Yu‐Kang , Pai Kai‐Jun , Chiu Huang‐Jen
Published: June 2008

A half‐bridge (HB) resonant inverter for driving a cold cathode fluorescent lamp (CCFL) backlight module with a piezoelectric transformer (PT) is analyzed in this paper. The resonant inductance of the HB inverter is expressed as a function of the load current, the load resistance and the PT circuit parameters. Also, the trans‐admittance of the PT‐CCFL combination network is measured to track the operating frequency for the HB resonant inverter, which may be varied due to the temperature rise of PT. The lamp driving current and power can thus remain almost constant in a wide temperature range. Experiments show that the observed results match the theoretical analyses. Copyright © 2008 John Wiley & Sons, Ltd.
Production, liquidity, and futures price dynamics
Authors: Wong Kit Pong
Published: June 2008

This study examines the optimal design of a futures hedge program for the competitive firm under output price uncertainty. All futures contracts are unbiased and marked to market in that they require interim cash settlement of gains and losses. The futures price dynamics follows a first‐order autoregression with a random walk serving as a special case. The firm's futures hedge program is constituted of an endogenous provision for premature termination, which depends on how the futures prices are autocorrelated. Succinctly, the firm voluntarily commits to premature liquidation of its futures position on which the interim loss incurred exceeds a predetermined threshold level if the futures prices are positively autocorrelated. In this case, the liquidity constrained firm optimally opts for an over‐hedge if its preferences exhibit either constant or increasing absolute risk aversion. If the futures prices are uncorrelated or negatively autocorrelated, the firm prefers to be liquidity unconstrained and thus adopts a full‐hedge to completely eliminate the output price risk. © 2008 Wiley Periodicals, Inc. Jrl Fut Mark 28:749–762, 2008
Do tax‐exempt yields adjust slowly to substantial changes in taxable yields?
Authors: Dudney Donna , Geppert John
Published: June 2008

This paper examines the profitability of two futures trading strategies: a municipal bond futures contract strategy and a spread strategy consisting of a municipal bond futures contract and a Treasury bond futures contract. Both strategies are designed to exploit a slow municipal yield adjustment following changes in Treasury yields. We find economically significant profits to both strategies. Average holding period returns per trade for both strategies tend to increase with the magnitude of the Treasury yield change. Profit distributions associated with various Treasury yield change thresholds tend to be positively skewed, and median profits are significantly lower than average profits. The profitability results are consistent with slow municipal yield adjustments. © 2008 Wiley Periodicals, Inc. Jrl Fut Mark 28:763–789, 2008
Nonparametric American option pricing
Authors: Alcock Jamie , Carmichael Trent
Published: June 2008

A nonparametric method is introduced to accurately price American‐style contingent claims. This method uses only historical stock price data, not option price data, to generate the American option price. The accuracy of this method is tested in a controlled experimental environment under both Black, F and Scholes, M (1973) and Heston, S (1993) assumptions, and an error‐metric analysis is performed. These numerical experiments demonstrate that this method is an accurate and precise method of pricing American options under a variety of market conditions. © 2008 Wiley Periodicals, Inc. Jrl Fut Mark 28:717–748, 2008
HDD and CDD option pricing with market price of weather risk for Taiwan
Authors: Huang Hung‐Hsi , Shiu Yung‐Ming , Lin Pei‐Syun
Published: June 2008

This study extends the long‐term temperature model proposed by Alaton et al. (2002) by taking into account ARCH/GARCH effects to reflect the clustering of volatility in temperature. The fixed variance model and the ARCH model are estimated using Taiwan weather data from 1974 through 2003. The results show that for HDD/CDD the call price is higher under ARCH‐effects variance than under fixed variance, while the put price is lower. Although different pricing methods are employed in pricing weather options, the effects of mean and standard deviation on option prices are mathematically proved to be the same as those in pricing traditional financial derivatives using the Black‐Scholes formula. © 2008 Wiley Periodicals, Inc. Jrl Fut Mark 28:790–814, 2008
Characterization of amplicons in neuroblastoma: High‐resolution mapping using DNA microarrays, relationship with outcome, and identification of overexpressed genes
Authors: Fix Anne , Lucchesi Carlo , Ribeiro Agnès , Lequin Delphine , Pierron Gaëlle , Schleiermacher Gudrun , Delattre Olivier , Janoueix‐Lerosey Isabelle
Published: June 2008

Somatically acquired chromosomal imbalances are a key feature of neuroblastoma, a heterogeneous pediatric solid tumor. Among these alterations, genomic amplification targeting theMYCNoncogene and observed in about 25–30% of the cases, strongly correlates with advanced stage and poor outcome. In this work, we have used BAC and SNP arrays as well as gene expression arrays to characterize amplifications in neuroblastoma. Eighty‐eight distinct BACs defining high‐level amplification events were identified in 65 samples, including 43 tumors and 22 cell lines. Although the highest recurrence was observed on chromosome 2, clones on chromosomes 8, 12, 16, and 17 also revealed genomic amplification in several samples. A detailed analysis of the 2p22‐2p25MYCNcontaining region indicated highly complex patterns in a number of cases. Coamplifications involvingMYCNand other regions were explored by FISH in three cell lines. High‐resolution arrays then allowed us to further refine the mapping of 25 amplicons in 19 samples, either reducing the size of a single continuous amplicon or increasing the complexity by highlighting multiple noncontiguous regions of amplification. Combined analysis of gene expression profiling and array‐CGH data indicated that 12 to 25% of the genes that are targeted by genomic amplification are actually over‐expressed in tumor cells, several of them having already been implicated in cancer. Finally, our results suggest that the presence of amplicons localized outside of chromosome 2, in addition toMYCNamplification, may be linked to a particularly severe outcome in neuroblastoma patients. © 2008 Wiley‐Liss, Inc.
Microarray‐based DNA profiling to study genomic aberrations
Authors: Waddell Nic
Published: June 2008

High throughput microarrays were initially developed to analyse the expression of many RNA transcripts in parallel. The technology has since been adapted to a variety of applications, one of which is the analysis of the genome to study DNA dosage and sequence content. Advances in microarray fabrication and completion of large‐scale genome sequencing projects have enabled the rapid development of affordable array‐based methods for high‐resolution genome‐wide assessment of DNA alterations. This review will describe the evolution of microarray assays to study genomic aberrations and will highlight how they have enabled researchers to gain insight into the biology of human diseases and how they will benefit research in the future. © 2008 IUBMB IUBMB Life, 60(7): 437–440, 2008
FUT7 antisense sequence inhibits the expression of FUT7/sLeX and adhesion between embryonic and uterine cells
Authors: Liu Shuai , Zhang Yuanyuan , Liu Yuejian , Qin Huamin , Wang Xiaoqi , Yan Qiu
Published: June 2008

Implantation is a complex developmental event that is initiated by recognition and adhesion of the embryo to the endometrial epithelium. sLeX is an oligosaccharide antigen acting as the ligand of L‐selectin, and is stage‐specifically expressed in the endometrial epithelium. The adhesion system mediated by L‐selectin and sLeX oligosaccharide plays an important role in this process. FUT7 is a key enzyme for sLeX synthesis, and the regulation of sLeX through FUT7 may influence maternal–fetal recognition. In this study, we observed the effect of FUT7 antisense oligodeoxynucleotide on the expression of FUT7 and sLeX, as well as adhesion in an in vitro implantation model consisting of the human uterine epithelial cell line RL95‐2 and the human embryonic cell line JAR. Results showed that the expression of FUT7 was significantly decreased, compared with controls, after FUT7 antisense oligodeoxynucleotide transfection into RL95‐2 cells, as determined by RT‐PCR, Western blotting, and indirect immunofluorescence. Synthesis of sLeX was also decreased, consistent with the FUT7 decrease, as shown by indirect immunofluorescence. The adhesion of embryonic cells to uterine epithelial cells was significantly reduced (P < 0.01) compared with the control. These data indicate that the use of a FUT7 antisense oligodeoxynucleotide can cause a significant reduction of both FUT7 and sLeX antigen, and thereby inhibit the adhesion of embryo cells to endometrium. This approach may provide a new way to regulate reproduction. © 2008 IUBMB IUBMB Life, 60(7): 461–466, 2008
Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase‐independent pathway
Authors: Croci Diego O. , Cogno Ingrid S. , Vittar Natalia B. Rumie , Salvatierra Edgardo , Trajtenberg Felipe , Podhajcer Osvaldo L. , Osinaga Eduardo , Rabinovich Gabriel A. , Rivarola Viviana A.
Published: June 2008

Survivin is recognized as an attractive target in cancer therapy because of its selective overexpression in the majority of tumors. Upregulated expression of this protein correlates with increased tumor grade, recurrence risk and decreased cancer patients survival. In this study, we assessed the efficacy of two survivin‐specific small interfering RNA (siRNA) constructs to inhibit T47D human breast cancer cell growth. After siRNA transfection, T47D cells showed a significant reduction in proliferation and survival exhibiting clear signs of apoptosis. pSil_1 that targeted exon 1 exhibited a stronger inhibitory effect on cell growth, and increased cell apoptosis compared to pSil_30 that targeted exon 4. Cell apoptosis was found to be mediated by translocation of the mitochondrial apoptosis inducing factor (AIF), while no changes were observed in caspase‐3 activation and Bid cleavage. Thus, silencing survivin expression using siRNA strategies represents a suitable therapeutic approach to selectively modulate the survival and growth of human breast cancer cells. J. Cell. Biochem. 105: 381–390, 2008. © 2008 Wiley‐Liss, Inc.
Issues and opportunities in accelerator mass spectrometry for stable isotopes
Authors: Matteson Sam
Published: June 2008

Accelerator mass spectrometry (AMS) has developed in the last 30 years many notable applications to the spectrometry of radioisotopes, particularly in radiocarbon dating. The instrumentation science of trace element AMS (TEAMS) that analyzes stable isotopes, also called Accelerator SIMS or MegaSIMS, while unique in many features, has also shared in many of these significant advances and has pushed TEAMS sensitivity to concentration levels surpassing many competing mass spectroscopic technologies. This review examines recent instrumentation developments, the capabilities of the new instrumentation and discernable trends for future development. © 2008 Wiley Periodicals, Inc., Mass Spec Rev 27: 470–484, 2008
Analysis of environmental stress response on the proteome level
Authors: Nesatyy Victor J. , Suter Marc J.‐F.
Published: June 2008

Thousands of man‐made chemicals are annually released into the environment by agriculture, transport, industries, and other human activities. In general, chemical analysis of environmental samples used to assess the pollution status of a specific ecosystem is complicated by the complexity of the mixture, and in some cases by the very low toxicity thresholds of chemicals present. In that sense, a proteomics approach, capable of detecting subtle changes in the level and structure of individual proteins within the whole proteome in response to the altered surroundings, has obvious applications in the field of ecotoxicology. In addition to identifying new protein biomarkers, it can also help to provide an insight into underlying mechanisms of toxicity. Despite being a comparatively new field with a number of caveats, proteomics applications have spread from microorganisms and plants to invertebrates and vertebrates, gradually becoming an established technology used in environmental research. This review article highlights recent advances in the field of environmental proteomics, mainly focusing on experimental approaches with a potential to understand toxic modes of action and to identify novel ecotoxicological biomarkers. © 2008 Wiley Periodicals, Inc., Mass Spec Rev 27: 556–574, 2008
Component evolution in a secure wireless sensor network
Authors: Bloznelis M. , Jaworski J. , Rybarczyk K.
Published: June 2008

We study a connectivity property of a secure wireless network that uses random pre‐distribution of keys. A network is composed of n sensors. Each sensor is assigned a collection of d different keys drawn uniformly at random from a given set of m keys. Two sensors are joined by a communication link if they share a common key. We show that for large n with high probability the connected component of size Ω(n) emerges in the network when the probability of a link exceeds the threshold 1/n. Similar component evolution is shown for networks where sensors communicate if they share at least s common keys. © 2008 Wiley Periodicals, Inc. NETWORKS, 2009
On the L(h, k)‐labeling of co‐comparability graphs and circular‐arc graphs
Authors: Calamoneri Tiziana , Caminiti Saverio , Petreschi Rossella , Olariu Stephan
Published: June 2008

Given two nonnegative integers h and k, an L(h, k)‐labeling of a graph G = (V, E) is a map from V to a set of integer labels such that adjacent vertices receive labels at least h apart, while vertices at distance at most 2 receive labels at least k apart. The goal of the L(h, k)‐labeling problem is to produce a legal labeling that minimizes the largest label used. Since the decision version of the L(h, k)‐labeling problem is NP‐complete, it is important to investigate classes of graphs for which the problem can be solved efficiently. Along this line of thought, in this article we deal with co‐comparability graphs, its subclass of interval graphs, and circular‐arc graphs. To the best of our knowledge, ours is the first reported result concerning the L(h, k)‐labeling of co‐comparability and circular‐arc graphs. In particular, we provide the first algorithm to L(h, k)‐label co‐comparability, interval, and circular‐arc graphs with a bounded number of colors. Finally, in the special case where k = 1 and G is an interval graph, our algorithm improves on the best previously‐known ones using a number of colors that is at most twice the optimum. © 2008 Wiley Periodicals, Inc. NETWORKS, 2009