bluuebunny/crossref_metadata_2025 huggingface dataset:
Modulated vacancy ordering in SrGe6−

x
(x≈0.45)
Authors: Schwarz Ulrich , Castillo Rodrigo , Wosylus Aron , Akselrud Lev , Prots Yurii , Wahl Bernhard , Doert Thomas , Bobnar Matej , Grin Yuri
Published: November 2018

The structural properties of modulated SrGe6−

x
(x≈0.45) were investigated by means of single-crystal and powder X-ray diffraction combined with quantum chemical calculations. The framework compound SrGe6−

x
adopts a defect variant of the EuGa2Ge4-type crystal structure. Samples of the binary compound with nominal compositions 0≤x≤0.5 were synthesized at pressures from 5 to 6 GPa and a temperature of typically 1400 K. The product reveals diffraction peaks of the EuGa2Ge4-type subcell plus additional reflections indicating an ordered superstructure. Detailed crystal structure analysis evidences the incommensurate nature of the superstructure and a modulation of the vacancy ordering in the germanium network. The computations have shown that the non-stoichiometric composition of the framework with its local defect organization affects the calculated charge of the strontium anions. Although the chemical composition is close to a charge-balanced situation, temperature-dependent resistivity measurements showed metal-type conductivity. At ambient pressure SrGe6−

x
decomposes exothermally and irreversibly at T=680(10) K into SrGe2 and germanium, indicating its metastable nature at ambient pressure.
Trabalho e produção associada ao turismo: tensões e rupturas no processo de construção da identidade de mulheres na comunidade rural Chã de Jardim
Authors: Oliveira Josilene Ribeiro
Published: November 2018

Este artigo traz uma reflexão sobre o trabalho como um valor moral para os sitiantes, em sua articulação com a dinâmica da reciprocidade e a hierarquização das relações sociais. Trata-se de um recorte da tese da autora. O objetivo geral é analisar a reinterpretação das práticas de trabalho a partir da participação das mulheres sitiantes no desenvolvimento da oferta turística na cidade de Areia - Paraíba. Os dados apresentados foram construídos a partir da etnografia da Comunidade Chã de Jardim e de entrevistas semidirigidas realizadas com 30 sitiantes, entre setembro de 2015 e março de 2016. No plano teórico os interlocutores privilegiados são: Klass Woortmann, Cynthia A. Sarti, Marcos Lanna e Marcel Mauss. Os resultados apontam que as mulheres são protagonistas no trabalho com turismo, ocupando a maioria dos postos e, inclusive, a liderança comunitária, o que lhes propiciou reconhecimento e elevação da autoestima. Porém, o trabalho das mulheres é percebido e ainda concebido como “ajuda” (complementar), estando subordinado à satisfação e à manutenção da estrutura hierárquica estabelecida. Apesar de não apontar uma ruptura definitiva com o modelo de família tradicional, a experiência de trabalho com o turismo revela a busca de valorização e autonomia das mulheres, bem como as tensões e contradições envolvidas nesse processo.
APRESENTAÇÃO: ETNOGRAFIAS SOCIOLÓGICAS DE UM MUNDO DO TRABALHO RECONFIGURADO
Authors: Robert Pedro , Lisdero Pedro , Scarpati Costa Elizardo
Published: November 2018

Os organizadores Pedro Robertt, Pedro Lisdero e Elizardo Scarpati Costa apresentam os artigos que compõem o dossiê "Etnografias de um mundo do trabalho reconfigurado"
INTOXICAÇÃO CÚPRICA ACUMULATIVA EM OVINO: TRATAMENTO E RECUPERAÇÃO (RELATO DE CASO)
Authors: Zaro Débora , Mikhailenko Thayane Santana , Loss Daiene Elisa , Bueno Flávia Umpierre , Melo Luciano Cavalheiro , De Castro Beck Carlos Afonso , De Araújo Rocha André Luiz , Redivo Cristine Bitencourt
Published: November 2018

A intoxicação por cobre é uma das principais causas de mortalidade por intoxicação em ovinos. Os sinais clínicos e anatomopatológicos são similares aos de outras doenças. Assim, vários casos tornam-se inconclusivos quando não são utilizadas técnicas analíticas no diagnóstico. O presente trabalho relata o caso de um carneiro da raça Hampshire Dow que foi encaminhado ao Hospital de Clínicas Veterinárias da Universidade Federal do Rio Grande do Sul com sinais clínicos de intoxicação por cobre. O animal apresentava apatia, inapetência, emagrecimento, dispneia, tosse, secreção nasal, urina e diarreia de coloração escura. O ovino foi adquirido numa feira de exposição de animais e havia permanecido em manejo intensivo recebendo quantidades de concentrado acima da exigência dietética nos dois meses anteriores e durante o evento. Quatro dias após o surgimento dos sinais clínicos o animal foi internado no hospital, foi estabelecida terapia de suporte com fluidoterapia, suplementação de aminoácidos e glicose. Administrou-se sulfato de sódio, molibdato de amônia, adsorvente de toxinas e protetores de mucosa. Após 34 dias de tratamento intensivo o paciente apresentou melhora do quadro clínico e recebeu alta. Baseado no histórico, sensibilidade da espécie, sinais clínicos, resultados dos exames laboratoriais, melhora do quadro clínico e resposta positiva à terapêutica, sugere-se o quadro de intoxicação cúprica acumulativa. Não foi realizada análise histoquímica específica para marcação de cobre. O trabalho consiste em revisão literária, características clínicas e laboratoriais da intoxicação, conduta para o tratamento e diagnóstico, contribuindo, portanto, para o entendimento da doença e redução da ocorrência de novos casos.
USE OF PROTEIN DIETS AS A SUPPLEMENT FOR AFRICANIZED BEES Apis mellifera
Authors: Romeu Pinto Mara Rúbia , Machado Medeiros de Albuquerque Pedro , Veleirinho Beatriz , Sequeira Gonçalves Vitoria , Farias Campos Vinicius , Casquero Cunha Rodrigo , Pereira Leivas Leite Fábio , Maraschin Marcelo
Published: November 2018

At the nature, bees consume pollen and nectar to obtain its nutrients (proteins, lipids, carbohydrates, vitamins, and minerals). Changes in bee pastures have occurred as green areas and forests have been replaced by agricultural areas affecting colony health and productivity. Because of this, the efficiency of artificial protein diets for the Africanized honey bee (Apis mellifera, L.) was evaluated - considering the total protein content of the hemolymph, weight of the bees, and dietary consumption. The crude protein of the diets ranged from 12.2 to 24.4%. Newly emerged workers were caged and kept in an incubator with controlled temperature and humidity until six days old, receiving diets and water ad libitum. Hemolymph was collected from 0- and 6-day-old workers. Comparing the diets, significant differences in the protein content in the hemolymph, bee weight, and diet consumption were found among the treatments. A diet composed of 20% sugarcane yeast, 20% textured soy protein, and 60% sucrose was the most efficient according to measures of total protein in the hemolymph, bee weight and diet consumption. The use of protein sources as a supplement for hives can be a safe and viable alternative for beekeepers.
EFEITO DO EXTRATO HIDROALCÓOLICO DE Polygonum hydropiperoides EM CÉLULAS ESPERMÁTICAS DE Sus scrofa domesticus
Authors: Giordani Claudia , Da Silva Cristine Cioato , Perera Soliane Carra , Barbosa Rafael Mielke , Pires Diego Martins , Corcini Carine Dahl , Varela Júnior Antônio Sérgio , Cleff Marlete Brum
Published: November 2018

Polygonum hydropiperoides é uma das plantas utilizadas como medicinal e que apresenta atividades biológicas confirmadas na dependência da composição química. Desta forma, estudos sobre a toxicidade e interação desta planta com as células são necessários, sendo os espermatozoides uma opção inovadora para a avaliação. Assim, o objetivo deste estudo foi determinar a composição química do extrato hidroalcoólico de P. hydropiperoides (PH) e a toxicidade em células espermáticas. Para a determinação da composição química do extrato foi utilizada a análise cromatográfica líquida de ultra eficiência. A toxicidade foi avaliada através da análise computadorizada da motilidade espermática de sêmen suíno doméstico (Sus scrofa domesticus), enquanto as alterações celulares foram analisadas por citometria de fluxo. Foram identificados no extrato vegetal um total de 17 compostos fenólicos destacando-se o ácido quínico e quercetina. Os parâmetros avaliados não sofreram alterações significativas nas concentrações de 1,5 até 6,2 mg.mL-1 independente do tempo de exposição ao extrato, sendo que a redução dos parâmetros ocorreu de forma progressiva ao aumento das concentrações (6,2 mg.mL-1 ≤ 12 mg.mL-1 ≤ 50 mg.mL-1 ≤ 100 mg.mL-1). Através da citometria de fluxo pode-se observar que em nível de estrutura celular, não foram observadas alterações significativas. As alterações provocadas pelo extrato podem sugerir os possíveis mecanismos de ação a serem explorados para aplicação clínica. O extrato hidroalcoólico de P. hydropiperoides, abundante em ácido quínico e quercetina, acarretou apenas em alterações na motilidade espermática, a partir de 12 mg.mL-1.
SOROPREVALÊNCIA PARA LEPTOSPIROSE EM SUÍNOS: UM ESTUDO EM ANIMAIS ABATIDOS EM PELOTAS/RS
Authors: Freitas Lais Santos , Machado Gilmar Batista , Dewes Caroline , Felix Samuel Rodrigues , Pacheco Paula Soares , Da Silva Éverton Fagonde
Published: November 2018

O objetivo deste estudo foi realizar um levantamento sorológico da leptospirose em suínos abatidos em frigorífico da cidade de Pelotas, RS. Das 108 amostras de soro suíno analisadas, 38,88% foram reagentes no teste de soroaglutinação microscópica (MAT). Dos 42 suínos reagentes, 45,24% eram provenientes da região de Rodeio Bonito, 26,20% da região de Pelotas, 14,28% da região de Horizontina e 14,28% da região de Santo Cristo. Os sorovares mais frequentes foram Canicola, Autumnalis e Copenhageni com 52,38%, 23,80% e 21,42% respectivamente. Quanto à titulação, os títulos mais altos foram de 1:800, observados contra os sorovares Canicola, Autumnalis e Bratislava. Com a soroprevalência relativamente alta em populações suínas revelada aqui, vê-se a importância do controle da leptospirose nos rebanhos suínos.
Ranosrednjovjekovni nalazi s lokaliteta Brekinjova Kosa (rezultati istraživanja 2011. i 2015. godine)
Authors: Koprivnjak Vedran , Madiraca Vinko , Miletić Martina , Zubin Ferri Tea , Bekić Luka
Published: November 2018

Tijekom dviju sezona zaštitnih arheoloških istraživanja gradine Brekinjova Kosa nedaleko od Gline, otkriveni su ostaci ranosrednjovjekovnog objekta (vjerojatno crkve) i nekropole s bogatim grobnim prilozima. Među nalazima se ističe grob unutar samog objekta (grob 4) koji se prema prilozima svrstava u skupinu najbogatijih ranosrednjovjekovnih grobova istraženih na području moderne hrvatske države. Osim metalnih nalaza evidentiranih u grobovima ističe se i određena količina ranosrednjovjekovne keramike pronađene u površinskim slojevima i zasebnim jamama na lokalitetu, a koja bi mogla pružiti podatke o eventualnom naselju populacije koja se ovdje pokapala. S obzirom na to da je okolica lokaliteta uglavnom arheološki neistražena, ovaj nalaz pruža važne podatke o razdoblju ranog srednjeg vijeka na predmetnom području.
Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe
Authors: Yukawa Masashi , Yamada Yusuke , Toda Takashi
Published: November 2018

The Kinesin-5 motor Cut7 in Schizosaccharomyces pombe plays essential roles in spindle pole separation, leading to the assembly of bipolar spindle. In many organisms, simultaneous inactivation of Kinesin-14s neutralizes Kinesin-5 deficiency. To uncover the molecular network that counteracts Kinesin-5, we have conducted a genetic screening for suppressors that rescue the cut7-22 temperature sensitive mutation, and identified 10 loci. Next generation sequencing analysis reveals that causative mutations are mapped in genes encoding α-, β-tubulins and the microtubule plus-end tracking protein Mal3/EB1, in addition to the components of the Pkl1/Kinesin-14 complex. Moreover, the deletion of various genes required for microtubule nucleation/polymerization also suppresses the cut7 mutant. Intriguingly, Klp2/Kinesin-14 levels on the spindles are significantly increased in cut7 mutants, whereas these increases are negated by suppressors, which may explain the suppression by these mutations/deletions. Consistent with this notion, mild overproduction of Klp2 in these double mutant cells confers temperature sensitivity. Surprisingly, treatment with a microtubule-destabilizing drug not only suppresses cut7 temperature sensitivity but also rescues the lethality resulting from the deletion of cut7, though a single klp2 deletion per se cannot compensate for the loss of Cut7. We propose that microtubule assembly and/or dynamics antagonize Cut7 functions, and that the orchestration between these two factors is crucial for bipolar spindle assembly.
Patrick Michel, Adam Possamai, and Bryan S. Turner (eds), Religions, Nations, and Transnationalism in Multiple Modernities
Authors: Mee Wendy
Published: November 2018

Patrick Michel, Adam Possamai, and Bryan S. Turner (eds), Religions, Nations, and Transnationalism in Multiple Modernities. New York: Palgrave Macmillan, 2017, pp. 235, ISBN: 978-1-137-59238-5.
Elizabeth Bucar, Pious Fashion: How Muslim Women Dress
Authors: Muez Nursheila Binte Abdul
Published: November 2018

Elizabeth Bucar, Pious Fashion: How Muslim Women Dress. Cambridge, MA: Harvard University Press, 2017, pp. ix + 235, ISBN: 9780674976160 (hbk).
Dennis Brown, Religious Studies for GCSE: Philosophy and Ethics Applied to Christianity, Roman Catholicism and Islam
Authors: Nurwanto Nurwanto
Published: November 2018

Dennis Brown, Religious Studies for GCSE: Philosophy and Ethics Applied to Christianity, Roman Catholicism and Islam. Cambridge: Polity Press, 2016, pp. xv + 302, ISBN: 978-1509504374 (pbk).
Complex proteinopathies and neurodegeneration: insights from the study of transmissible spongiform encephalopathies
Authors: Piccardo Pedro , Asher David M.
Published: November 2018

ABSTRACT Protein misfolding diseases are usually associated with deposits of single “key” proteins that somehow drive the pathology; β-amyloid and hyperphosphorylated tau accumulate in Alzheimer's disease, α-synuclein in Parkinson's disease, or abnormal prion protein (PrPTSE) in transmissible spongiform encephalopathies (TSEs or prion diseases). However, in some diseases more than two proteins accumulate in the same brain. These diseases might be considered “complex” proteinopathies. We have studied models of TSEs (to explore deposits of PrPTSE and of “secondary proteins”) infecting different strains and doses of TSE agent, factors that control incubation period, duration of illness and histopathology. Model TSEs allowed us to investigate whether different features of histopathology are independent of PrPTSE or appear as a secondary result of PrPTSE. Better understanding the complex proteinopathies may help to explain the wide spectrum of degenerative diseases and why some overlap clinically and histopathologically. These studies might also improve diagnosis and eventually even suggest new treatments for human neurodegenerative diseases.
Análisis de co-palabras aplicado a los artículos muy citados en Biblioteconomía y Ciencias de la Información (2007-2017)
Authors: GALVEZ Carmen
Published: November 2018

Resumen Se identifican las relaciones entre los conceptos y las áreas temáticas principales dentro de la categoría Biblioteconomía y Ciencias de la Información de Web of Science, en el periodo 2007-2017, utilizando la herramienta analítica “Essential Science Indicators”. Partiendo de los artículos altamente citados, la metodología consistió en la aplicación de análisis de co-palabras así como técnicas estadísticas de análisis multivariante y visualización a través de un mapa de la ciencia. Los resultados principales mostraron que las áreas de mayor interés para los investigadores fueron los estudios sobre la Web 2.0 basados en la participación colaborativa de los usuarios, la evaluación de las actividades científica, las métricas alternativas, o Altmetrics, desarrolladas en las plataformas sociales y académicas, la seguridad y confianza en los entornos virtuales y, por último, la aplicación de plataformas digitales en el comercio electrónico.
Geração de indicadores para periódicos científicos abertos
Authors: MARCHIORI Patrícia Zeni , BETTONI Eduardo Michelotti , CARVALHO Marcelo Batista , APPEL Andre Luiz
Published: November 2018

Resumo Equipes editoriais envidam constantes esforços no cumprimento de requisitos qualitativos e quantitativos exigidos por agências indexadoras de periódicos científicos. Aqueles periódicos ainda não consolidados nas suas áreas de interesse - e consequentemente ainda não inseridos nas bases de dados que produzem indicadores - normalmente deixam de coletar, calcular e analisar dados que venham a auxiliá-los na tomada de decisão. Assim, questiona-se a possibilidade e as condições de geração de indicadores de desempenho, utilizando-se os dados presentes na plataforma Open Journal Systems - enquanto ambiente de editoração e publicação de periódicos científicos -, em conjunto com outras fontes de dados sob domínio ou alcance dos seus gestores. Nesse sentido, o objetivo deste estudo foi explorar uma metodologia para geração de tais indicadores, integrando a criação e uso de uma base de referências com a consulta aos critérios de avaliação de periódicos verificados na literatura e, ainda, com o processo de extração de metadados. Tal metodologia, aplicada ao periódico “AtoZ: novas práticas em informação e conhecimento”, resultou na exploração de um corpus de referências em BibTeX e na conversão dos metadados existentes no arco temporal de 2011 a 2016, permitindo o planejamento, criação e análise de indicadores que, potencialmente, podem auxiliar na visão estratégica do periódico. O conjunto de dados coletados e o teste dos indicadores propostos reforçam a necessidade de preenchimento integral e constante dos metadados, bem como as vantagens do uso do formato BibTeX, além de permitir a sequência da investigação, voltada ao entendimento, avaliação e comparação do periódico com outros títulos disponíveis.
EFFECT OF CAPILLARY PRESSURE IN NANOBUBBLES ON THEIR ADHERENCE TO PARTICLES DURING FROTH FLOATATION. PART 6. INFORMATIVITY OF BUBBLE SPREADING CURVES
Authors: Melik-Gaikazyan V. I. , Emel’yanova N. P. , Dolzhenkov D. V.
Published: November 2018

Spreading curves (SCs) are calculated for bubble diameters (de) 1 mm and 1 μm on substrates with different wettability: from maximumhydrophobicity (Г) to maximum-hydrophilicity (Ф) as well as incompletely wettable (Нх) ones, where x = 0,8; 0,6; 0,4 and 0,2 is the fraction of an ionized collector monolayer under the bubble. The calculations were based on the results of a numerical solution of the Laplace equation in the form of 12-figure tables such as Bashforth and Adams tables. They demonstrate firstly that the SCs obtained are identical to those calculated for bubbles with de = 20 and 10 nm, and thus SC shapes are unchanged in the 105 range, i.e. virtually for all flotation bubbles, and secondly that SC shapes and their mutual arrangement depend on substrate wettability. Spreading curves clearly illustrate the advantages of substrate Г adhesion to the bubble in comparison with substrate Ф, and for Нх an advantage of the substrate with a larger fraction of x. It is quantitatively shown that even with small spreading of nanobubbles adhered to the particle, their adherence force increases billion times so that large bubbles can fix on their increased perimeters and lead the particle to flotation. If, however, the adhesion of large bubbles to nanobubbles occurs before spreading of the latter, they will come off together, and the particle will not float. This mechanism was used for particle flotation in the processes of the Bessel brothers, Potter-Delpra and two processes of F. Elmor in the late 19th and early 20th centuries. The prospect of increasing the productivity and cost-efficiency of modern froth flotation by activating particle flotation not only with nanobubbles but also with larger bubbles is considered.
Simple 3D imaging of biogenic silica structures by fluorescent microscopy v1
Authors: Colin Sebastien
Published: November 2018

This protocol describes how to prepare, stain and mount biogenic silica particles (opaline from diatoms, Radiolaria, sponges spicules, phytolith...) for 3D imaging with fluorescent microscopy. The protocol is fast, convenient and inexpensive. Hence it could be a relevant alternative to X-ray computed tomography or photogrammetry.
Nuclear DNA purification from recalcitrant plant species for long-read sequencing v2
Authors: Jones Ashley , Borevitz Justin
Published: November 2018

Evolution has driven genetic diversity of life on Earth, but also created highly complex genomes that are difficult to sequence. Current draft genomes can have thousands to hundreds of thousands of contigs rather than chromosomes, containing incorrect assemblies, gaps and errors. With rapid advances in long-read technologies, it is becoming possible to resolve complex genomes, including repetitive, polyploid plant genomes. Despite the technology being available, a challenge persists: the extraction of pure high molecular weight DNA suitable for long-read sequencing. This is particularly true of recalcitrant native Australian trees such as Eucalypts and Acacias. To resolve this, firstly we optimised a density gradient and detergent based nuclei extraction to limit reads from high copy count plastid genomes. Secondly, we optimised a gentle high molecular weight DNA extraction free of columns and high centrifugation, to limit DNA fragmentation. Finally, the DNA was purified and size selected by gel electrophoresis. For sequencing, we adopted the portable MinION sequencer from Oxford Nanopore Technologies. Using these approaches, we have been obtaining >9 gigabases of sequencing from a single MinION flow cell, including reads over 100 kb in length. Such ultra-long reads assist the assembly of high quality genomes, from telomere to telomere.
Surgery for advanced oropharyngeal cancer
Authors: Karpenko A. V. , Sibgatullin R. R. , Boyko A. A. , Chumanikhina N. S. , Lomteva E. Yu. , Lavrova M. V. , Kostova M. G. , Nikolayeva O. M.
Published: November 2018

The study objectiveis to assess the results of this approach and identifications of factors that may influence the effectiveness of such an approach.

Materials and methods. Since 2009 through 2016 72 patients with stage III and IV aged between 42 and 77 years underwent upfront surgery.Anatomical sites included 34 (46 %) tonsil, 24 (33 %) base of tongue and 14 (21 %) soft palate cases. Transcervical sparing the mandible,mandibulectomy and transoral approaches were used in 42 (58 %), 11 (15 %) and 7 (10 %) patient, respectively. Total glossectomy was performed in 4 (5.5 %) cases. Tumor extension necessitated extended laryngectomy in 8 patients (11.5 %). Primary closure of the pharyngeal wound was possible in 30 patients (42 %). Reconstruction with distant flaps was performed in the remaining 42 patients. Both free (anterolateral thigh – 19, radial forearm flap – 10) and flaps with axial blood supply (pectoralis major – 9, supraclavicular flap – 4) were used. There were 6 T1, 12 T2, 28 T3 and 20 T4 tumors; 62 patients were N-positive: N1 – 10 cases, N2 – 51, N3 – 1. Positive surgical margins were diagnosed in 13 cases (18 %) including 3 cases of R2 resection. Adjuvant radiation therapy with or without chemotherapy was completed in 45 patients (63.4 %). Survival was calculated according to Kaplan–Mayer method.

Results.There was 1 death in early postoperative period. Mean follow-up for the remaining patients (n = 71) was 27 months (1–94). Median survival was 27 months (95 % CI 11.5–42.5); 3-year overall survival was 44 %; 33 out of 34 still alive patients are capable to take food orally. Only 1 (2.9 %) patient is gastrostomy tube dependent. Univariate analysis revealed that positive margins (p <0.0001) and completeness of combined treatment (p <0.01) are the main factors that have statistically significan impact on prognosis.

Conclusion.Combined approach with upfront surgery is one of the main treatment modalities for advanced oropharyngeal cancer. Modern reconstructive options and strict adherence to a proper surgical technique give a high chance for a valuable rehabilitation for the vast majority of patients. Scrupulous planning of the resection of the primary tumor based on modern imaging techniques and encouraging patients to complete all prescribed treatments are the main physician-related factors that influence survival outcome.
PREDICTORS OF RE-EXPLORATION FOR BLEEDING AFTER CORONARY ARTERY BYPASS GRAFT AND VALVE SURGERY
Authors: Mohammad Amanj
Published: November 2018

Background 

A significant number of patients undergoing cardiac surgery require re-exploration for postoperative bleeding. 

Objectives 

The aim of this study is to find out the predictors of re-exploration for such bleeding.

Patients and Methods

Over a 5-year period (January 2010-December 2014) 1,565 patients underwent open-heart surgery in Slemani Cardiac Hospital, Sulaimaniyah, Iraq. Fifty seven patients (3.6%) were identified as having a significant bleeding after coronary artery bypass graft (CABG) and/or valve operations requiring urgent exploration within few hours. The medical records of these patients were retrospectively reviewed. 

Results

There were 36 males and 21 females. The mean age was 61.8±7.5 years. The majority of patients had CABG (n=41, 71.9%) while the remainder 16 patients (28.1%) had valve operations. The mean time interval between the primary cardiac operation and re-exploration was 3.17 ± 1.5 hours. Twenty nine patients (50.9%) had a drop in hemoglobin level. Thirteen patients (22.8%) had a fall in arterial blood pressure (ABP) ± raised central venous pressure (CVP). CVP was elevated in 9 patients (15.8%). The mediastinum was widened on chest radiograph in 4 occasions (10.5%). More than half of the patients (n=32, 56.1%) had arterial hemorrhage. The earliest re-exploration was required for arterial bleeding while bleeding of unknown origin was the latest to be re-explored. Decreased ABP and massive blood drainage were associated with early re-exploration, while radiological evidence of widened mediastinum and decreased Hb level were linked to late re-exploration. 

Conclusion

A drop in ABP and massive blood drainage seem to be good predictors for exploration.
EVALUATION OF THYROID FUNCTION TESTS IN POSTMENOPAUSAL OSTEOPOROTIC PATIENTS IN SULAIMANI GENERAL TEACHING HOSPITAL
Authors: Mahwi Taha , Sahib Barham
Published: November 2018

Background 

Osteoporosis is a common disorder in the elderly and postmenopausal women due to loss of estrogen that increases the risk of fracture and disability. Hyperthyroidism can cause osteoporosis either due to the effect of thyroid hormones or suppressive effect of Thyroid-stimulating hormone on the bone.

Objectives 

The aim of this study was to examine the association between serum thyroid-stimulating hormone levels and osteoporosis in Postmenopausal women in Sulaimani General Teaching hospital.

Patients and Methods

The study was done prospectively, we enrolled one hundred and sixty-two postmenopausal women who underwent Dual-energy X-ray absorptiometry scan in Sulaimani bone Densitometry department for routine health surveillance, thyroid function test was done for them after applying exclusion criteria.

Results

The mean thyroid stimulating hormone level (1.9 ± 1.7) vs (2.7 ± 2.30), body mass index and incidence of diabetes mellitus of the osteoporotic group is lower in comparison to those with normal bone mineral density.

Conclusion

In this study results suggest that low normal serum thyroid stimulating hormone level might be a potential risk factor for the osteoporosis in non-obese elderly women, however further prospective, large-scale, randomized controlled studies are warranted to fully establish these results.
ALLRED SCORE DIRECTLY ASSOCIATED TO BODY MASS INDEX IN KURDISH PREMENOPAUSAL WOMEN WITH BREAST CANCER
Authors: Ameen Hazha
Published: November 2018

Background 

Obesity has been documented as an important prognostic factor and increased mortality with each successive increase in body mass index (BMI). It is unclear whether these associations differ among breast cancer subtypes.

Objectives 

To know the association of the Allred score which has both predictive and prognostic value, with the body mass index in Kurdish Premenopausal women with breast cancer.

Patients and Methods

This study carried out at Hiwa hematology/oncology hospital of Sulaimani between June 2007 to December of 2015. Age, menopausal status, hormone receptor, Her-2 neu status height, weight, and body mass index were studied. Allred score by immunohistochemistry of all breast cancer patients was retrospectively analyzed.

Results

We conducted a population-based case-case study consisting of 519 women diagnosed with invasive breast cancer. Mean age of the studied group was 47.3±9.2 years. Mean menopausal age was 51±3 years; almost two-thirds of whom were premenopausal. Mean BMI of breast cancer patients was 30.1±5.6 kg/m2; 47% were obese. There was a strong association between high BMI and breast cancer in the age period of 40 to 49 years (p=0.03). The obese patient had a high tumor grade, ki67 and stage III disease. Strong expression of both Estrogen and progesterone receptors were observed in obese premenopausal patients.

Conclusion

Obese women usually presented with an increased risk of breast cancer in premenopausal women, advanced stage, and the majority of them had positive hormonal receptor status (ER/PR) Estrogen Receptor /Progesterone Receptor. Fortunately, obese linked to high Allred score with good response to hormonal therapy and better survival.
SUBCLINICAL LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN HYPERTENSIVE PATIENTS IN SLEMANI CITY USING 2D ECHOCARDIOGRAPHY
Authors: Hamakarem Omed , Hassan Kamaran , Saeed Dana
Published: November 2018

Background 

Diastolic dysfunction refers to when the diastole part is abnormal. The ventricles do not properly relax and become stiff meaning they cannot fill with blood properly. This causes blood to “dam up” in other parts of the body. The pressure in the ventricles then increases as blood from the next heartbeat tries to enter. Diastolic dysfunction is a common problem, with many people aged older than 70 years having the condition

Objectives 

To detect subclinical left ventricular diastolic dysfunction in hypertensive patients with preserved ejection fraction using 2D echocardiography.

Methods

This is a cross-sectional study that was carried on 80 hypertensive patients referred to slemani cardiac hospital and medical emergency outpatient clinic for evaluation and treatment of hypertension and 80 age and sex-matched healthy volunteers as a control group. All subjects underwent conventional echocardiographic examination and assessment of diastolic dysfunction by 2D echocardiography according to updated Europian guidelines for diastolic dysfunction

Results

A total of one hundred sixty (160) individuals were included in the final analysis. Mean age was 55.03±7.67SD years. Males accounted for 51.9% (n=83) of the studied sample and 48.1% (n=77) were females. Fifty percent (n=80) were hypertensive (cases) and the other 50% (n=80) were non-hypertensive (controls).hypertensive patients have significantly higher rates of diastolic dysfunction (22 cases vs 12) and LVH (19 vs 5) than non-hypertensives, they also have higher mean lateral annulus velocity (8.83±2.41vs10.21±2.62 ) and TR velocity(2.28±0.37vs2.11±0.11) but smaller mean LA volume.

Conclusion

Impairment of diastolic function detected by 2D echocardiography was significantly higher in hypertensive patients (with and without LVH) compared to nonhypertensive patients. Early detection of diastolic dysfunction in hypertensive patients is necessary to prevent diastolic heart failure which is the major type of heart failure in hypertensive patients.
A CASE REPORT OF METACHRONOUS METASTATIC TESTICULAR CANCER OF COLORECTAL ORIGIN
Authors: Namiq Kadhim , Mohaildeen Fadhil , Abdalla Shalaw , Mansour Mateen , Mahmood Kawa
Published: November 2018

Metastatic testicular neoplasm is rare and carries poor prognosis compared to primary germ cell tumours. Colorectal cancers usually metastasize to the liver, lungs, skeletal system, brain and adrenals, whereas only 8% of all metastatic testicular lesions are from colorectal cancer origin. Several histopathological features and mechanisms of metastasis to the testicles have been stated in the literature.
Cloning of PpKAR2 and PpPDI1 genes promoters from yeast Pichia pastoris, an evaluation of their activity and efficacy for the heterologous genes expression
Authors: Tsygankov Mikhail A. , Padkina Marina V.
Published: November 2018

Background. Yeast Pichia pastoris is successfully used in biotechnology, with their help synthesized various compounds. Promoters are a key factor in the productivity of an expression system, since they determine the expression level of a heterologous gene.
The aim of our work was to study the promoter regions of the PpKAR2 and PpPDI1 genes and to evaluate their use for effective expression of heterologous genes.
Materials and Methods. To evaluate the activity of promoters, we used a reporter system based on the structural gene of acid phosphatase of yeast Saccharomyces cerevisiae PHO5. To determine the effect of overproduction of native and heterologous protein on the activity of the promoters under study, we used the producer strains of P. pastoris protein disulfide isomerase and maize delta-zein. To evaluate the effectiveness of the use of the promoters under study for the expression of heterologous genes, we have expressed under their control a gene encoding human interferon-alpha16.
Results. The promoters of the yeast genes PpKAR2 and PpPDI1 were cloned. Their activity was compared with the promoter of the PpAOX1 gene in the native strains, as well as in strains with overproduction of native and heterologous proteins. Under the control of these promoters, the gene encoding human interferon-alpha 16 is expressed.
Conclusion. The promoters studied were weaker than the promoter of the AOX1 gene, but increase their activity in response to the production of heterologous proteins and can be used to express heterologous genes.
Predictors of cholesterol gallstone formation among inhabitants of Port Harcourt in Nigeria
Authors: Wichendu Promise N. , Amadi Collins
Published: November 2018

Background: Various clinical and biochemical parameters have been hypothesized to predict cholesterol gallstone formation. Hence, this study was structured to evaluate the degree of some of these suggested predictors among inhabitants of Port Harcourt in Nigeria.Methods: This was a retrospective study of the clinical and biochemical parameters of 42 cholesterol gallstones formers within a tertiary hospital in Nigeria. Records of age, gender, weight, height, calculated body mass index and plasma biochemical parameters (total cholesterol, total bilirubin, and total calcium) of cholesterol gallstone formers from 1st January 2008 to 31st December 2017 were abstracted from medical and laboratory records and analysed using SPSS version 20.Results: There were more females (70%) than males (30%) with a ratio of 2.3:1. The age ranged from 31-64 with mean 46.78±9.33. Obesity was observed among 40.5% of study population. Female gender (OR = 2.823; 95% CI = 2.446-3.200; p<0.001), obesity BMI status (OR = 1.534; 95% CI = 1.436 - 1.632; p = 0.012) and abnormal plasma cholesterol status (OR = 3.011; 95% CI = 2.916 - 3.106; p<0.001) were significant predictors of cholesterol gallstone formation. Abnormal plasma cholesterol status was the strongest of the predictors with AUC of 0.920 (p<0.001), seconded by female gender (AUC = 0.889; p<0.001) and obesity BMI status (AUC = 0.834; p<0.001).Conclusions: Abnormal plasma cholesterol status is the strongest independent predictor of cholesterol gallstone formation, seconded by female gender and high BMI status, among inhabitants of Port Harcourt in Nigeria.
ART, MASS COMMUNICATION AND UTOPIA
Authors: ALİOĞLU Nazan
Published: November 2018

In our day that the end of
history, end of art and death of socialism are declared, we need new dreams of
happiness more than ever. At this point, what is the role of art? The utopic
sense of art that produces dreams of happiness, in other words, union of art
and politics, may be evaluated over Walter Benjamin’s ‘’The Work of Art in the
Age of Technical Reproducibility’’.After 1960s, the course of
plastic arts has changed. The inferior part of art has become politicized art
especially fort he sake of ruling the masses. And the high part of art has been
taken into the public relations activities of large corporations and serve in
that direction. Demystification, auralessness and the lack of philosophy
accompanying these has made art additionally a means of public relations and
publicity, that is to say, art strengthens the marketing, sales relations of
multinational companies.

Under the guidance of
Benjamin’s powerful article, this paper investigates the conceptions mentioned
above by means of art’s serving the political mass culture with the
collaboration of mass media or the hegemonic power of art and again art’s
serving the global capital with public relations and publicity purposes will be
discussed within the context of Benjamin’s understanding of art-aesthetics and
utopia; relationship of art and mass; mass art and hegemony; relationship of
art and communication; within the context of aura again, philosophy and art.
AGRICULTURA NA AMAZÔNIA LEGAL E SUA RELAÇÃO COM O DESMATAMENTO: UMA ANÁLISE A PARTIR DOS CENSOS DEMOGRÁFICOS E AGROPECUÁRIOS DE 1996 E 2006.
Authors: Bispo Lorenna Grasielle , Pimentel Geyza Alves
Published: November 2018

: Este trabalho intitulado “Agricultura na Amazônia Legal e sua Relação com o Desmatamento: Uma Análise a Partir dos Censos demográficos e agropecuários de 1996 e 2006” procurou tratar da temática Agricultura, Amazônia e Desmatamento. Foram escolhidos os anos de 1996 e 2006, por serem os mais recentes dados dos censos publicados nestes dois anos. É sabido que no Brasil, os projetos desenvolvimentistas do Governo Federal reservaram para a Amazônia Brasileira uma enorme erosão marginal, tendo como principais causas diretas no desmatamento a agropecuária, principalmente no que diz respeito a atividade madeireira. Nosso objeto de estudo é a Amazônia Legal, e o problema que norteia este trabalho é o de saber se os impactos ambientais causados pela atividade de agricultura na Amazônia contribuem de maneira significativa para o desmatamento e seus efeitos. E a fim de responder ao referido problema, contextualizamos o tema sob os aspectos teóricos e para a construção prática desta pesquisa, consultamos os Censos Demográficos e Agropecuários do IBGE.
Expediente
Authors: Agrogeoambiental Revista
Published: November 2018

Expediente
Effects of the First Phase of Cardiac Rehabilitation Training on Self-Efficacy among Patients Undergoing Coronary Artery Bypass Graft Surgery
Authors: Borzou Seyed Reza , Amiri Sasan , Salavati Mohsen , Soltanian Ali Reza , Safarpoor Gholamreza
Published: November 2018

Background: Heart surgery is vital for patients with coronary artery diseases that do not respond to drug treatments. We aimed to determine the effects of the implementation of the first phase of a cardiac rehabilitation program on self-efficacy in patients after coronary artery bypass graft surgery (CABG).
Methods: This clinical trial study was conducted on 60 post-CABG patients by convenience sampling method in 2016. Those selected were randomly assigned to intervention (n=30) and control group (n=30). Overall, 72 hours after CABG, the first phase of the cardiac rehabilitation program both in theory and in practice (face-to-face and group methods) was conducted. Data were collected using a self-efficacy questionnaire completed by the patients in 3 stages: before the intervention, at discharge, and at 1 month after discharge. Data was analyzed by using analysis of covariance and repeated measures.
Results: The mean of age in the intervention and control groups was 61.60±11.72 and 57.97±13. 4 years, respectively. There were 16 (53.3%) male patients in each group. The mean score of self-efficacy was not significantly different between the 2 groups before the intervention (P=0.076), whereas it had a meaningful statistical difference between the 2 groups at discharge and 1 month afterward (P<0.001).
Conclusion:  The implementation of the first phase of the cardiac rehabilitation program not only augmented self-efficacy in regard to independent daily activities but also lessened the need for the second phase of the program among our post-CABG patients.
La Montaña Sagrada. Aspectos sobre la legitimación del poder en el Clásico maya
Authors: García Capistrán Hugo
Published: November 2018

El concepto de la Montaña Sagrada fue muy importante para las sociedades mesoamericanas y de otras culturas del mundo. Diversos estudios demuestran que en él se conjugaron ideas sobre los ancestros, la abundancia, la riqueza, el territorio y el poder. Entre los mayas prehispánicos y los actuales esto no fue la excepción. En el presente trabajo se aborda este concepto y sus formas de representación gráfica y se propone que fue uno de los símbolos de poder más importantes dentro del aparato de legitimación del ajaw. Los mascarones zoomorfos witz, tanto en pintura como en escultura, fueron utilizados como medios para expresar la relación entre el gobernante maya, la Montaña Sagrada, los ancestros, el territorio y todas las riquezas que en ella se resguardan.
Retomando saberes contemporáneos. Un análisis del panorama actual de la meliponicultura en Tabasco.
Authors: Chan Mutul Guelmy Anilú , Aldasoro Maya Elda Míriam , Sotelo Santos Laura Elena , Vera Cortés Gabriela
Published: November 2018

La meliponicultura, practicada por distintas culturas, está constituida de diversos saberes contemporáneos (conocimientos, prácticas y creencias en constante producción y reproducción). El presente estudio aborda el estado actual de la meliponicultura en Tabasco, considerándola como patrimonio biocultural. Se realizaron entrevistas semiestructuradas sobre la relación que tienen las personas con las abejas que cultivan y los saberes contemporáneos que poseen. Se registraron 101 meliponicultores en 15 de los 17 municipios, el 24% pertenece a un grupo indígena. El municipio con mayor número de meliponicultores es el de Tenosique (37), seguido de Tacotalpa (14) y Balancán (11). Se cultivan once especies de meliponinos. Se entrevistaron 81 meliponicultores y se clasificaron en tres tipos de acuerdo a su objetivo: tradicionales (52%), resignificados (42%) y conservacionistas (6%). Lo más común es tener la colmena en troncos (52%), un 32% las tiene en cajas y un 16%, tanto en troncos como en troncos modificados y cajas. El 11% de los meliponicutores sabe dividir sus colmenas. La miel, la cera y la colmena tienen diferentes usos: comestibles, medicinales y religiosos. La relación de los meliponicultores con las abejas es compleja y va más allá de lo utilitario; esta práctica implica saberes contemporáneos sobre la etología, ecología y morfología de las especies de meliponinos. Hay un declive de la meliponicultura en Tabasco por lo que es apremiante tener un mayor conocimiento de ésta y fomentarla entre las nuevas generaciones a partir de un diálogo de saberes.
La cooperación intermunicipal como estrategia de ordenación y desarrollo territorial en espacios transfronterizos: la Agrupación Europea de Cooperación Territorial Duero-Douro
Authors: Manero Miguel Fernando
Published: November 2018

Texto resumen.
A Genetic Algorithm Based Feature Selection for Handwritten Digit Recognition
Authors: Ahlawat Savita , Rishi Rahul
Published: November 2018

Background:

The data proliferation has been resulted in large-scale, high dimensional data
and brings new challenges for feature selection in handwriting recognition problems. The practical
challenges like the large variability and ambiguities present in the individual’s handwriting style
demand an optimal feature selection algorithm that would be capable to enhance the recognition accuracy
of handwriting recognition system with reduced training efforts and computational cost.

Objective:

This paper gives emphasis on the feature selection process and proposed a genetic algorithm
based feature selection technique for handwritten digit recognition.

Methods:

A hybrid feature set of statistical and geometrical features is developed in order to get the
effective feature set consist of local and global characteristics of sample digits. The method utilizes a
genetic algorithm based feature selection for selecting best distinguishable features and k-nearest
neighbour for evaluating the fitness of features of handwritten digit dataset.

Results:

The experiments are carried out on standard The Chars74K handwritten digit dataset and
reported a 66% reduction in the original feature set without sacrificing the recognition accuracy.

Conclusion:

The experiment results show the effectiveness of the proposed approach.
Role of Nanomedicine in Treatment of Brain Cancer
Authors: Verma Shivani , Utreja Puneet , Kumar Lalit
Published: November 2018

Background:

Drug delivery to cancerous brain is a challenging task as it is
surrounded by an efficient protective barrier. The main hurdles for delivery of bioactive
molecules to cancerous brain are blood brain barrier (BBB), the invasive nature of gliomas,
drug resistance, and difficult brain interstitium transportation. Therefore, treatment
of brain cancer with the available drug regimen is difficult and has shown little improvement
in recent years.

Methods:

We searched about recent advancements in the use of nanomedicine for effective
treatment of the brain cancer. We focused on the use of liposomes, nanoparticles,
polymeric micelles, and dendrimers to improve brain cancer therapy.

Results:

Nanomedicines are well suited for the treatment of brain cancer owing to their
highly acceptable biological, chemical, and physical properties. Smaller size of nanomedicines
also enhances their anticancer potential and penetration into blood brain barrier
(BBB).

Conclusion:

Recently, nanomedicine based approaches have been developed and investigated
for effective treatment of brain cancer. Some of these have been translated into
clinical practice, in order to attain therapeutic needs of gliomas. Future advancements in
nanomedicines will likely produce significant changes in methods and practice of brain
cancer therapy.
IDENTIFIKASI AIRTANAH ASIN BERDASARKAN PENDUGAAN GEOLISTRIK DI PESISIR KOTA CILACAP JAWA TENGAH
Authors: Purnama Setyawan , Cahyadi Ahmad , Febriarta Erik , Khakhim Nurul , Prihatno Hari
Published: November 2018

Airtanah merupakan salah satu sumberdaya air potensial yang dapat digunakanuntuk memenuhi kebutuhan air manusia. Pemanfaatan airtanah yang berlebihan diwilayah pesisir seringkali menyebabkan terjadinya intrusi air laut. Penelitian ini bertujuanuntuk mengetahui keterdapatan airtanah asin di Pesisir Kota Cilacap. Analisis dilakukandengan pendugaan geolistrik. Analisis data dilakukan dengan menggunakan softwareIP2Win. Hasil analisis menunjukkan bahwa airtanah asin terdeteksi pada titik A, C, D danG.Kata Kunci: Airtanah Asin, Pesisir, Geolistrik, Kota Cilacap
WIND ENERGY AS AN ALTERNATIVE ENERGY SOURCE(Study Case at South Coastal of Yogyakarta Special Province, Indonesia)
Authors: Widiyanti Baiq Liana
Published: November 2018

The need of larger quantity of energy to fulfill the demand of energy, especially thefossil fuel, forced the government of almost all nation try to find the new kind of energy orknown as alternative energy resources. Fossil fuel as non-renewable energy resources wouldbe decreased by the time if the using of it not under controlled. This kind of energy resourcesused to handle almost all the people need of energy, such as for domestic uses, industrial,tourism, etc. The used of fossil fuel for that purposed mostly for generated the electricitypower (by built the power plant). Many natural energy resources can used to generateelectricity power plant, but there always be some advantages and bad impact, especially forthe environments. One of environmental friendly alternative energy resources is exploitingthe form of wind power.Keyword: alternative energy, wind energy, windmills farms, human well-being.