bluuebunny/crossref_metadata_2025 huggingface dataset:
Supervisory optimal control using machine learning for building thermal comfort
Authors: Abdufattokhov Shokhjakhon , Mahamatov Nurilla , Ibragimova Kamila , Gulyamova Dilfuza , Yuldashev Dilyorjon
Published: February 2023

For the past few decades, control and building engineering communities have been focusing on thermal comfort as a key factor in designing sustainable building evaluation methods and tools. However, estimating the indoor air temperature of buildings is a complicated task due to the nonlinear and complex building dynamics characterised by the time-varying environment with disturbances. The primary focus of this paper is designing a predictive and probabilistic room temperature model of buildings using Gaussian processes (GPs) and incorporating it into model predictive control (MPC) to minimise energy consumption and provide thermal comfort satisfaction. The full probabilistic capabilities of GPs are exploited from two perspectives: the mean prediction is used for the room temperature model, while the uncertainty is involved in the MPC objective not to lose the desired performance and design a robust controller. We illustrated the potential of the proposed method in a numerical example with simulation results.
Umwendungen ins Jetzt. : Ein Systematisierungsvorschlag zur Barock- und Frühneuzeitrezeption der Gegenwartslyrik
Authors: Meierhofer Christian
Published: February 2023

Abstract Der Aufsatz beschäftigt sich mit der Barock- und Frühneuzeitrezeption der Gegenwartslyrik und macht einen Vorschlag zu deren Systematisierung. Die historischen Bezüge finden vor allem auf vier Ebenen statt, die mit jeweils einem Beispiel belegt werden:
Bewusstseinsgeschichte bei Ernst Meister, Gattungsgeschichte und Gattungspoetik bei Jan Wagner, Wissens- und Kulturgeschichte bei Marcel Beyer sowie Konzepte von Autor:innenschaft bei Thomas Kling und Marion Poschmann.The article deals with the reception of the Baroque and Early Modern
Age within contemporary poetry and makes a proposal for its systematization. The historical references especially occur on four levels which are demonstrated by one example respectively: the history of consciousness regarding Ernst Meister, genre history and poetics regarding Jan Wagner, knowledge
and cultural history regarding Marcel Beyer, as well as the conception of authorship regarding Thomas Kling and Marion Poschmann.
Selbstevaluation. : Germanistische Gutachten der Wendezeit an der Humboldt-Universität zu Berlin
Authors: Thomalla Erika
Published: February 2023

Abstract Der Beitrag untersucht, inwiefern sich die Zäsur der Jahre 1989/90 darauf auswirkte, wie die deutsche Literaturwissenschaft der DDR sich selbst und ihren Nachwuchs beurteilte. Anhand von Dissertations- und Habilitationsgutachten, die in den 1980er und 1990er
Jahren an der Humboldt-Universität zu Berlin verfasst wurden, wird gezeigt, dass der Wandel der Evaluationspraktiken nur bedingt mit den politischen Umwälzungen kongruent war. Schon in den 1980er Jahren lässt sich eine Tendenz zu Entideologisierung und zur fachlichen Ausdifferenzierung
beobachten, während umgekehrt in den 1990er Jahren durch die Adaption neuer poststrukturalistischer Theorien unter veränderten Vorzeichen an Fragestellungen der DDR-Germanistik angeschlossen werden konnte.The article examines to what extent the caesura of the years 1989/90 affected
how the discipline of German literary studies in the GDR evaluated itself and its young scholars. Based on the analysis of dissertation and habilitation reports written at Humboldt University in Berlin in the 1980s and 1990s, the article shows that the change in evaluation practices was only
partially congruent with the political upheavals. A tendency towards de-ideologization and disciplinary differentiation can already be observed in the 1980s, while conversely, in the 1990s, the adaptation of new post-structuralist theories under changed auspices made it possible to connect
to issues of GDR German studies.
Ost-/West-Germanistik an der Universität Halle (ca. 1980−2000). : Zwischen Expansion, Transformation und Schrumpfung
Authors: Rottmann Mike
Published: February 2023

Abstract Diese Studie verknüpft den Forschungsstand zur Transformation der DDR-Hochschulen mit einer Skizze zur Entwicklung der Germanistik an der Universität Halle. Im Zentrum steht die Frage, welche konkreten Auswirkungen die Evaluationen im Spannungsfeld von
Wissenschaft und Politik hatten.This study builds on existing research on the transformation of universities in the GDR with an outline of the development of Germanistik at the University of Halle. Its focus is on the state’s evaluations of the faculty, and it asks the question:
what effect did the evaluations have in the conflict between scholarship and politics?
Axillary solitary fibrous tumor as an incidental finding in the context of marginal B-cell limphoma.
Authors: Plazas Font PJ , Aleixandre Barrachina M , Laguna Sastre JM
Published: February 2023

El tumor fibroso solitario, denominado previamente hemangiopericitoma, es un tumor de partes blandas, mesenquimal y cuya localización es ubicua y su curso indolente debido a su naturaleza anatomopatológica.

En el caso aquí presentado, la paciente había sido diagnosticada de Linfoma Folicular con afectación adenopática generalizada que, tras la remisión de la neoplasia, presentó una masa axilar. Esto supuso un reto en el diagnóstico diferencial de la supuesta linfadenopatía, debido a la comorbilidad, edad y sexo de la paciente. La biopsia con aguja gruesa diagnosticó esta masa como un tumor fibroso solitario y se realizó exéresis quirúrgica de la misma. No precisó tratamientos sistémicos posteriores y en el seguimiento a los seis meses no hubo recurrencia del proceso linfoproliferativo ni de la tumoración fibrosa.
Endovascular treatment in acute mesenterica ischemia
Authors: Pérez Reyes M , Turiño Luque JD , Gutiérrez Delgado MP , Botello García F , Aranda Narváez JM , Santoyo Santoyo J
Published: February 2023

Introducción: La trombosis venosa mesentérica superior es una enfermedad rara que debuta con sintomatología inespecífica. Su diagnóstico en estadios iniciales es fundamental para instaurar tratamiento anticoagulante precoz y si precisa, tratamiento endovascular para evitar cirugía.

Métodos: Presentamos el caso de un paciente de 42 años acude por dolor abdominal. En la exploración destacaba dolor en hemiabdomen derecho, sin irritación peritoneal y estable hemodinámicamente. La analítica mostraba 22.540leucocitos/mm3. El TAC presentaba trombosis en la vena porta y mesentérica superior y engrosamiento del íleon con débil realce de pared. Ante la estabilidad se inició tratamiento anticoagulante y posteriormente trombectomía mecánica, manteniendo un catéter para fibrinolisis.

Resultados: A las 72horas del alta hospitalaria acude a urgencias por dolor abdominal. Se realizó TAC abdominal objetivando perforación intestinal y persistencia de la trombosis. Se decidió laparotomía urgente. Presentaba perforación y placas de necrosis intestinal. Se realizó resección intestinal.

Discusión: La trombosis venosa mesentérica aguda es una forma rara pero grave de isquemia mesentérica. La etiología puede ser identificada en el 75% de pacientes. Su presentación clínica varia ampliamente, lo que dificulta el diagnóstico y retraso del tratamiento. Las mejoras en las técnicas de imagen permiten un diagnóstico precoz y un tratamiento no quirúrgico. Aunque no hay un consenso, el objetivo primordial es evitar el infarto transmural, la perforación y peritonitis. Aunque no hay consenso en el tratamiento de la isquemia venosa mesentérica hay series que describen el manejo endovascular con trombectomía mecánica y farmacológica como medidas iniciales para evitar la resección intestinal con resultados alentadores.
Cholecystoenteric fistula as a cause of biliary ileus: tomographic findings
Authors: Avilez-Arias JM , Cabral-Martínez A
Published: February 2023

Introducción: El íleo biliar es una complicación poco común de la colecistolitiasis, representa <0.1% de causa de íleo.

Objetivos: Describir las características de íleo biliar, manifestaciones clínicas, opciones de abordaje diagnóstico y terapéutico.

Caso clínico: Se presenta caso de paciente femenino de 39 años de edad, con cuadro clínico de oclusión intestinal, en estudio tomográfico se identifica neumobilia, dilatación de asas intestinales, así como presencia de imagen de atenuación cálcica de hasta 4 cm de diámetro. Se realiza laparotomía identificando presencia de lito en ileon terminal a 40 cm de válvula ileocecal, realizando enterotomía y cierre primario. Se egresa sin complicaciones a las 96 horas del evento quirúrgico.

Discusión: En un 75-83% los litos son eliminados a través de una fístula bilioentérica. El sitio de impactación más común es ileon 50-60%. Se presentan manifestaciones inespecíficas, la tomografía axial computarizada tiene sensibilidad mayor 90% para el diagnóstico.

Conclusiones: El uso de la tomografía axial computarizada brinda datos específicos para el diagnóstico de íleo biliar, realizar procedimiento en dos etapas para resolución de íleo biliar y cierre de fístula colecistoentérica conlleva menor mortalidad, en este caso representó una opción segura para el tratamiento.
Coil Parameter Analysis in Wireless Electric Vehicle Charging
Authors: Ghimire Kshitij
Published: February 2023

The hassle of using plug-in charging for electric vehicles (EVs) such as connecting charger to the port of vehicles, risk of getting electrocuted during rain, dirty and oily charging cable etc. can be eliminated using wireless/induction power transfer (IPT). It can be made smart and automated. Hence, IPT can be considered the future of EV charging. However, the technology is just emerging and there are a lot of limitations at present. The major problems are less efficiency caused by coil misalignment and air gap, and the electro-magnetic field generated around the coils which possesses greater risk for human health. These can be improved by selecting the types of coils and shields which produce maximum magnetic flux between the coils whereas reduce the flux outside the coils. In this research, the strength of magnetic fields produced by various types of coils (circular, square and hexagonal) were simulated in Ansys Maxwell 3D to understand their features and to know which coil is the best for high power transfer efficiency. Similarly, the effects of using ferrite and aluminum shields for leakage reduction, by varying their thickness, were studied. Finally, the leakage flux values were simulated at very high currents to understand their behavior in such conditions.
The Impact of Using New Technologies on Student Progress and Development
Authors: Paterdi Georgia , Skoura Spridoula , Skraparlis Athanasios , Ntalianis Klimis
Published: February 2023

This paper focuses on the use of new technologies in educational practice. Despite the notion that students' familiarity with technological tools is essential for their learning development, the main question is still the following: does the utilization of technology affects the learning process ?The impact of using new technologies and tools on students’ learning achievements can be determined based on students’ progress in individual cognitive subjects, on students’ commitment, as well as on the attitudes, perceptions and readiness of teachers towards the utilization of technology. This paper explores whether and to what extent new technologies contribute to the strengthening of general education, special education and intercultural education (Roma students) students’ knowledge and skills. It appears that new technologies in classrooms seem to support educational practices. Teachers realize that their students use ICT as sources of reference, investigation and communication, while the frequent use of these tools effectively motivates students' commitment to learning and development.
MATHEMATICAL MODELING FOR RAINFALLPREDICTION THROUGH RULE BASE FUZZY INFERENCE SYSTEM USING MATLAB: A CASE STUDY IN RAIPUR DISTRICT
(CHHATTISGARH STATE)
Authors: Singh Priyanka , Pal Chaman , Netam Nisha
Published: February 2023

In human life, Weather forecasting is a very important and required field because in our country maximum people depend upon agriculture. The agricultural economy is largely based upon irrigation and rainfall. For analyzing the productivity of crops rainfall prediction is required and necessary for all farmers. In the present work, we use a rule-based fuzzy inference system (FIS) is employed to forecast day-wise concentrations in the ruler area of the Raipur district. This forecasting model was developed by using the 2 year period July 2016 and July 2017 and the evaluation of the model was achieved through a series of well-established evaluation parameters and methodologies. The evaluation reveals that the FIS models give the best forecasting values of approximately 87 to 88 percent. This will be more accurate as compared to the previous models. For a generation model, we take five parameters: Average temperature, wind direction, pressure, entire cloud cover, and corresponding humidity are the input variable for our model, each parameter consist of three membership functions. The data is used two years metrological data of the rural area of Raipur district (Chhattisgarh state). Our model is based on thirty-two If-Then rules and fuzzy reasoning. The output variable has three membership functions (Light, Medium, and Heavy Rainfall) which are assigned as (0 - 100) percentages for rainfall prediction given in day-wise. The result is in high concurrence, with the actual data.
CHARACTER ASSESSMENT AND DEVELOPMENT OF A TEST BATTERY IN INDIAN CONTEXT
Authors: Tiwari Sushil Kumar , Masih Aejaz
Published: February 2023

In practice, character assessments are focused on cognitive domain. The students are supposed to answer some questions from the book/s or learning program/s of character education. However, these tests do not qualify as the ‘character-assessment’ rather become a memory test of character. In order to assess whether character is incorporated in life, the specification of some domains is needed. Character is basically a concept of affective domain and quantifying it in accordance with its nature was a major objective of present study. ‘Educating for character’ is a global dream that has been stipulated as one of the educational outcomes in all countries. The study presumes that cultural context adequately shapes the character. So, the themes of character were identified and revalidated in Indian context. The paper justifies the quantification of character putting the contrary views. It also attempts to present the systematic steps for development of a ‘character assessment battery’.
Antenatal Compliance Relationship Care with Anxiety of Pregnant Women in Time Pandemic Covid-19
Authors: Fatimah Sitti , Musni Musni , Fatmasanti A. Ulfa , Rahmadani Kiki Reski
Published: February 2023

Pregnant women, who are at a higher risk of getting the coronavirus than other populations, have felt the psychological effects of the COVID-19 pandemic. Avoiding antenatal care (ANC) appointments due to anxiety puts the mother and fetus at risk for complications like undiagnosed bleeding at any point in the pregnancy. The purpose of this study is to examine whether or not pregnant women's fear about the Covid 19 epidemic affects their likelihood of keeping up with their scheduled ANC checkups. Analytical approaches based on cross-sectional studies. During April and May of 2021, investigators visited the Sibulue Health Center in Bone Regency. The demographic requirements are met by the responses of 48 pregnant women in their second and third trimesters who are able to explain their sentiments and anxieties. Twenty-eight pregnant women (58.3%) and nine pregnant women (18.0%) who did not suffer anxiety made frequent ANC visits to healthcare facilities throughout the Covid-19 epidemic. Among pregnant women, 18 (37.5%) had anxiety and were not attending ANC on a regular basis. Nine pregnant women (n = 9) did not report experiencing any anxiety, however two of them did not obtain consistent ANC. Using a chi-square test, we found a significance level of 0.001. (p 0.05). Women's worry during pregnancy was associated with their use of prenatal care services during the Covid-19 pandemic.
Microbial and Physicochemical Evaluation of Water Sourced from the Diobu Neighborhood Water Scheme, Port Harcourt, Nigeria
Authors: Amadi-Ikpa Chidi , Awari Victoria
Published: February 2023

The microbial and physicochemical evaluation of water sourced from the Diobu Neighbourhood Water Scheme (DNWS) in Port Harcourt, Nigeria was investigated due to some skepticism by households in the area concerning the water. Inhabitants disinfect their sourced drinking water using chemical agents as well as other crude measures to control microbes. Sixty water samples were collected from two household groups; household group 1- 4 and 5-8 persons (each group had 30 samples each) and analyzed for physiochemical and microbial property using standard laboratory procedure. Heterotrophic bacteria, total coliform, fecal coliform and heterotrophic fungi had mean ± standard deviation counts of 219.5 ± 6.0 x 103, 29 ± 1.0 x 101, 21 ± 3.0 x 101 and 105 ± 3.0 x 102CFU/ml for household group size 1- 4 persons respectively, while household size group 5-8 persons had mean ± standard deviation counts of 890 ± 1.0 x 103, 55 ± 3.0 x 101, 24 ± 8.0 x 101 and 81 ± 2.0 x 102 CFU/ml  for heterotrophic bacteria, total coliform, fecal coliform and heterotrophic fungi respectively. The water samples obtained from the household size from 1-4 persons had temperature that ranged from 28 to 30.50C while the water samples from homes with household size of 5-8 had temperature range from 26 to 300C. The physiochemical result reported no dissolve or suspended solid and turbidity. The hydrogen ion concentrations (pH) of water samples obtained from household size group 1-4 persons was 5.0 while that of the water samples in household size group 5-8 persons ranged from 5.0 and 6.0. There was no chlorine, bromine, magnesium and calcium elements in the water samples obtained from the homes’ water samples. Thus, drinking water from household size group 5-8 were more laden with microbes of medical importance. However, physico-chemical examination showed acceptability despite the alleged interference of chemical.
Gait Analysis Using Principal Component Analysis and Long Short Term Memory Models
Authors: R. Maheswari , Venkatasubbu Pattabiraman , Raja A. Saleem
Published: February 2023

Human analysis and diagnosis have become attractive technology in many fields. Gait defines the style of movement and gait analysis is a study of human activity to inspect the style of movement and related factors used in the field of biometrics, observation, diagnosis of gait disease, treatment, rehabilitation, etc. This work aims in providing the benefit of analysis of gait with different sensors, ML models, and also LSTM recurrent neural network, using the latest trends. Placing the sensors at the proper location and measuring the values using 3D axes for these sensors provides very appropriate results. With proper fine-tuning of ML models and the LSTM recurrent neural network, it has been observed that every model has an accuracy of greater than 90%, concluding that LSTM performance is observed to be slightly higher than machine learning models. The models helped in diagnosing the disease in the foot (if there is injury in the foot) with high efficiency and accuracy. The key features are proven to be available and extracted to fit the LSTM RNN model and have a positive outcome.
Role of Artificial Intelligence and Machine Learning in Drug Discovery and Drug Repurposing
Authors: Quazi Sameer , Fatima Zarish
Published: February 2023

Drug designing and repurposing is the most important field in the pharmaceutical industries and biomedical sciences. Because the challenges caused by drug such as low retention time, sensitivity can affect the efficacy of developmental process. As AI or ML has proven to be a potential activity in the health and biomedical sciences and from previous research it has found that AI can learn new data and transform it into the useful knowledge. So, in field of pharmacology, the aim is to design more efficient and novel vaccines using this method which is also cost effective. The underlying fact is to predict the molecular mechanism and structure for increased likelihood of developing new drugs. Clinical, electronic, and high-resolution imaging datasets can be used as inputs to aid the drug development niche. Moreover, the use of comprehensive target activity has been performed for repurposing a drug molecule by extending target profiles of drugs which also include off targets with therapeutic potential providing a new indication.
Cyberwar
Authors: Rafi Sumbul , Imtiaz Nasheed
Published: February 2023

Invasion, terrorist attacks, drone strikes, insurgency and counterinsurgency, civil strife, and foreign intervention have already spread around the world, but war is now spreading and intensifying in a new form waged across digital networks: cyberwar. This war is fought through the use of computers and the internet. Today, the central part of organizational activities has been converted to digital format. Cybercriminals are continually developing new attack types, tools, and strategies that enable them to access settings that are more complicated or well-controlled, do more harm, and even remain undiscovered. This chapter discusses the history of cyber war, its emergence, and the different forms of cyberattacks and various repercussions of cybercrime, including its influence on the health of organizations, the psychological and social threats it poses to workers, and other outcomes. Cybercrime is defined and exposed by specialist literature.
The Effect of the Russian-Ukraine War on Turkey's Economy and Financial Markets
Authors: Tetik Nevzat , Albulut Ilhan Ilker
Published: February 2023

Russia-Ukraine political relations, which have a long history, moved to a de facto dimension with Russia's invasion of Ukraine on February 24, 2022. This study focuses on the financial effects of the war's aftermath rather than its political repercussions. The authors examine the financial indicators of Turkey and interpret them in comparison with the global outlook and studies analyzing the financial effects in this process. Changes in the stock and bond markets are compared with global data to paint a picture of Turkey's exposure.
The States' Reflexes in This War and Struggle of the Middle East Countries Over the COVID-19 Pandemic in the Soft and Hard Wars Started All Over the World
Authors: Keskin Oğuz , Chaychi Semsari Mortaza , Gedik Ahmet , Badalov Gudrat , Bikari Somayyeh
Published: February 2023

The economic crisis and the increasing severity of public health problems have reached different dimensions with their rapid spread in the Middle East. Therefore, the Middle East, in a broad sense, presents a war with the pandemic crisis. Middle Eastern countries face this war and silent death. What could be its role and reflex? Although there is no way to deal with the rapid spread of COVID-19, we are still determining where the economic consequences will lead. It is still too early to draw definite conclusions. COVID-19 has made dramatic changes in the Middle East region and has achieved secondary financial results.
AI-Based Sales Forecasting Model for Digital Marketing
Authors: Biswas Biswajit , Sanyal Manas Kumar , Mukherjee Tuhin
Published: February 2023

Sales prediction with minute accuracy plays a crucial role for an organization to sustain amidst the global competitive business environment. The use of artificial intelligence (AI) on top of the existing information technology environment has become one of the most exciting and promising area for any organizations in the current era of digital marketing. E-marketing provides customers to share their views with other customers. In this paper, the authors proposed a model which will be helpful to the digital marketers to find out the potential customers to extract value from customer feedback. The proposed model is based on artificial neural network and will make it possible to identify the customer demand depending on previous feedback and to predict the future sales volume of the product. The authors tried to utilize AI, mainly neural networks (NNs), to construct an intelligent sales prediction and also to apply ANNs for prediction regarding sales of mobile phone (Redmi, Note 6 Pro) one month ahead depending on customer feedback on two e-commerce platform, namely Amazon.in and Snapdeal.in.
Blockchain-Based Traceability of Counterfeited Drugs
Authors: Rai Bipin Kumar , Srivastava Shivya , Arora Shruti
Published: February 2023

In the healthcare industry, providing a vital backbone for services is critical. The supply chain is a complex network that crosses organizational and geographical borders. In the healthcare business, counterfeit pills are one of the primary reasons for the harmful impact on human health and financial loss. Thus, pharmaceutical supply chains and end-to-end tracking systems are the recent research in healthcare. In this paper, the authors propose blockchain-based traceability of counterfeited drugs (BBTCD) that implements tracking of counterfeited drugs using smart contracts on the Ethereum blockchain. They offer a solution to fully decentralize the tracking by storing BBTCD on IPFS (inter planetary file system) to provide transparency and cost-effectiveness.
Biosynthesis of Silver Nano/Micro-Particles Using Sambiloto (Andrographis paniculata) Leaves Extract: Effect of AgNO3 Solution Concentrations
Authors: Chafidz Achmad , Hidayat Pratikno , Maulana Sabda , Ramadhan Eric H. , Prasetiawan Haniif , Kaavessina Mujtahid , Hendrawati Nanik
Published: February 2023

Silver nano/micro particles have been successfully produced via biosynthesis using sambiloto (Andrographis paniculata) leaves extract as the reductor agent. The obejctive of current was to study the effect of four different AgNO3 solution concentrations (i.e. 0.0125, 0.025, 0.05, 0.075 M) on the production of silver nano/micro particles via biosynthtesis. The sambiloto extract concentration used in this study was 0.5% w/v. The silver nano/micro particles produced via biosynthesis was characterized using UV-Vis spectrophotometer and Scanning Electron Microscopy (SEM). The UV-Vis analysis results showed that absorbance peaks for all four samples were observed at wavelength around 450 nm, which can be attributed to the presence silver nano/microparticles. The absorbance peak values for all samples were 0.1115; 0.0876; 0.052; 0.0424 for AgNO3 solution concentration of 0.0125; 0.025; 0.05; 0.075 M, respectively. The UV-Vis analysis results could also qualitatively conclude that the size of silver nano/micro particles produced at lower AgNO3 solution concentration were smaller than the size of silver nano/micro particles produced at higher AgNO3 solution concentration. In the other hand, SEM image showed that the size of silver particles prepared using AgNO3 solution concentration of 0.075 M was in the range of 5 – 10 μm, hence it can be called silver micro-particles. It was assumed that the size of silver nano/micro particles produced at higher AgNO3 solution concentration were bigger than the size of silver nano/micro particles produced at lower AgNO3 solution concentration.
Preliminary Study of Modified Fluorescent Silica Nanoparticles for the Detection of IgY Antibody
Authors: Apriyani Firda , Julyansyah Darmawan , Angelina Marissa , Randy Ahmad , Manurung Roberth V. , Yuliarto Brian , Jenie Siti Nurul Aisyiyah
Published: February 2023

Biosensors must display high sensitivity and selectivity with fast response and be cost-effective. Silica nanoparticles are profoundly promising as versatile signal platforms opening up new possibilities for bioassays and dynamic units in biosensing systems. Fluorescent silica nanoparticles (FSNP) may be a key nanomaterial for labeling antibodies or antigens for biosensor application. Integration FSNP with functional molecules utilizing different surface modification techniques can bring out great improvements such as selective recognition, sensitive detection, and signal amplification because FSNP can bind with a large number of dye molecules within a silica matrix. The FSNP conjugated with anti-IgY can be applied for the detection of IgY antibody. FSNP was fabricated using the sol-gel method with hydrosilylation techniques for silica surface modification. N-H of amide groups from FSNP-anti-IgY ware observed in the FTIR spectra at 1648 cm-1 indicating that the conjugation was successful. The fluorescence intensity of FSNP-anti-IgY after detection of IgY was applied for immunodetection and measured using fluorescence spectroscopy. The intensity of FSNP-anti-IgY was 156.82, 368.31, and 648.00 a.u for the 0.05, 0.1, 0.5 µg/ml of the sample concentrations, respectively. The results showed that the modified FSNP-anti-IgY may be used for the fluorescence detection of antibodies.
Hashimoto's Thyroiditis
Authors: Raj Nishant , Phatak Suresh , Singh Rohan Kumar , Singh Varun
Published: February 2023

Thyroiditis is a general term for several inflammatory thyroid disorders ranging from autoimmune, infective, and drug induced to ionizing radiation. Ultrasound is the imaging modality of choice in the evaluation of thyroid-related pathologies. B-mode and color Doppler provide for a noninvasive and sensitive method in the evaluation of thyroiditis. Elastography is a recent modality of ultrasound. It helps in differentiating benign from malignant diseases. A definite diagnosis is often not possible on ultrasound alone, correlation of ultrasonography findings with elastography and clinical and biochemical parameters help us reach an appropriate diagnosis in most of the cases and further imaging is seldom warranted.
Application of Multiplex Real-Time Polymerase Chain Reaction in Diagnosis of Intestinal Parasitic Infection among Anemic Pregnant Women
Authors: Gupta Vivek , Zahiruddin Quazi Syed , Gaidhane Abhay , Deshpande Prajakta , Tambekar Anil
Published: February 2023

Background:

Intestinal parasitic infection can cause anemia in pregnant women and is a major public health problem. Ascariasis, amebiasis, hookworm, giardiasis, and trichuriasis are common intestinal infestations causing anemia. The study detects them by using multiplex real-time polymerase chain reaction (PCR).

Methods:

Stool samples were collected, transported, DNA extraction was done followed by multiplex real-time PCR was performed using specific primers and probes for their detection. The results so obtained were compared with results of microscopy.

Results:

A total of 234 pregnant women were enrolled in the study, of which 82.5% were anemic. Among them, parasites were detected by multiplex real-time PCR such as Ascaris lumbricoides in 73%, Ancylostoma duodenale in 8%, Entamoeba histolytica in 17%, Giardia duodenalis in 2%, and Trichuris trichiura 0%. All pregnant women with intestinal parasitic infection were anemic. Multiplex real-time PCR showed a high detection rate as compared to microscopy (100% vs. 14.7%). Polyparasitism was detected in 11% of cases using multiplex real-time PCR.

Conclusion:

Multiplex real-time PCR enabled the detection of intestinal parasites in pregnant anemic women with distinct advantage over microscopy. It can potentially be used in an epidemiological surveillance study and can potentially influence the treatment in practice for intestinal parasitic infection causing anemia in pregnant women.
An Unusual Cause of Vocal Fold Cyst in a 15-Year-Old Boy
Authors: Swain Santosh Kumar , Dubey Debasmita
Published: February 2023

Vocal fold cysts are benign lesions of the larynx. Vocal fold cysts can be unilateral or bilateral and often confused with vocal nodules, particularly when symmetrical. The most common clinical presentation of this lesion is hoarseness of voice. The vocal fold cyst is usually secondary to vocal abuse. Endoscopic examination or videostroboscopy is an important tool for clinical confirmation of the vocal fold cyst. Transoral microlaryngeal surgery followed by speech therapy is an ideal treatment option for vocal fold cysts. Playing with a flute for a prolonged period is rarely reported with vocal fold cyst. Here, we report a case of true vocal fold cyst I in a 15-year-old boy who regularly practices flute.
Small Dense Low-Density Lipoprotein or Low-Density Lipoprotein for Cardiovascular Disease in Indians
Authors: Shah Komal , Varna V. P. , Thomas Nimi Elizabeth
Published: February 2023

Background:

We aimed to assess the association of small dense low-density lipoprotein (sdLDL) – a novel lipid marker for cardiovascular disease (CVD) risk estimation in Indians with the meta-analysis approach.

Methods:

Various databases, namely PubMed, MEDLINE, and EMBASE, were used to identify the prospective studies showing an association between CVD risk and lipid profile in the Indian population. Heterogeneity was assessed using Q and I
2 statistics, and data were expressed using the standardized mean difference (SMD) with 95% confidence interval (CI).

Results:

After database search, six eligible studies assessing levels of sdLDL and LDL in Indian patients with premature CVD were identified. Level of sdLDL was found to have positive relation with CVD risk in Indians (SMD = 1.352, 95% CI: 0.744–1.96 mg/dL, I
2 94.04%, P < 0.001) along with LDL (SMD = 0.680, 95% CI: 0.180–1.180 mg/dL) levels. However, the degree of association was greater with sdLDL.

Conclusions:

The current meta-analysis clearly identifies sdLDL as the better marker of premature CVD in Indians, especially in case of normal values of classical markers such as LDL.
Down Syndrome and its Oral Effects in Saudi Arabian Region
Authors: Alkahtani Fawzia Haif
Published: February 2023

The most prominent congenital syndrome is Down syndrome (DS). With the greatest number of births of all chromosomal disorders, it is the most well-known reason of physical as well as intellectual impairment. A comparatively elevated incidence of Down syndrome has been discovered in Saudi Arabia. Only few papers have been undertaken thus far describing the features of face and other oral features of Saudi Down syndrome subjects. To review the available literature on Down syndrome and it's oral effects in Saudi Arabia region. Down syndrome also described as trisomy of chromosome 21. It is a genetic autosomal inherited condition i.e non-sex chromosomal disorder that affects one in six hundred to one in two thousands live births in various populations and is marked by a deficit in physical and intellectual development. Due to the comparative elevated incidence of DS in Saudi Arabia—1 in every 554 live births—DS subjects were specifically chosen for this review of literature. There are now more people with DS as a result of the lowered mortality rate and rising incidence in Saudi Arabia population. The most noticeable craniofacial features are found in DS patients, along with other distinguishing physical and systemic manifestations. Midface deficit, prognathism of mandible, depressed position of nasal bridge, slanting of eyes, folds at the epicanthic region, condition of hypotelorism in ocular area, and strabismus constitute the documented craniofacial characteristics. Muscle hypotonia also affects the perioral muscles, which results in a lowering of the mouth's angle. A comparatively elevated incidence of Down syndrome has been discovered in Saudi Arabia. Only few papers have been undertaken thus far describing the features of face and other oral features of Saudi Down syndrome subjects. It can be concluded that individuals with Down syndrome in Saudi Arabia had a significantly higher incidence of facial as well as cranial features in comparison to the normal healthy counterparts. By using the search algorithms “(Down syndrome and dental caries, periodontal diseases), “(Down syndrome and deformity within oral structures), “(Down Syndrome and problems in occlusion and Craniofacial structures).”The researcher searched the Cochrane Central Systematic Reviews Registry, ISI Web of Science, and Medline without language restriction up to July 2022. Only few papers have been undertaken thus far describing the features of face and other oral features of Saudi Down syndrome subjects. It can be concluded that individuals with Down syndrome in Saudi Arabia had a significantly higher incidence of facial as well as cranial features in comparison to the normal healthy counterparts.
Radiographic and Magnetic Resonance Imaging-based Evaluation of Supraspinatus Impingement Syndrome – A Narrative Review
Authors: Manoj Megha , Kashikar Shivali Vaibhav , Dhande Rajasbala Pradeep , Mishra Gaurav Vedprakash
Published: February 2023

Shoulder pain is a common debilitating problem affecting both young as well as elderly people. Its prevalence varies from 6-11% in young adults to 16-25% in elderly. Supraspinatus Impingement syndrome is the most common impingement syndrome causing shoulder pain. Primary or secondary reduction of subacromial distance due to morphological differences of acromion, acromial osteophytes, superior migration of humeral head etc. are predisposing factor for supraspinatus impingement. The aim of this review article is to understand the relevant anatomy of subacromial space and review supraspinatus impingement syndrome and its association with subacromial distance and acromion morphology. Literature search was conducted on PubMed and Google Scholar databases using MeSH terms – 'subacromial distance', 'Supraspinatus Impingement syndrome', 'Acromion', 'MRI'. 8 studies from 2006 to 2021 have been included for review. It was observed that subacromial distance and lateral acromial angle are lower in patients with supraspinatus impingement compared to the general population. Whereas the acromion index is higher in impingement syndrome. Evaluation of supraspinatus impingement syndrome can be done reliably using specialized radiographic views and MRI. Extrinsic factors like reduced subacromial distance and acromion morphology are predisposing factors for impingement of supraspinatus tendon.
Treating Periodontal Disease for Preventing Adverse Pregnancy Outcomes
Authors: Sayeed Ghousia , Varghese Sheeja S.
Published: February 2023

To study systematic studies and analyze how treating periodontal disease might help to avoid unfavorable pregnancy outcomes. One of the most prevalent oral conditions affecting people is periodontitis. It has been observed that around thirty percent of the people in some populations. Periodontitis is found in 5–20% of the pregnant woman. It has been found that the management of periodontitis is safe in pregnancy through scaling and root planning. Preterm delivery and periodontal disease now have a clear link, according to current research. This finding has garnered significant interest of the clinicians and researchers. Five systematic reviews were judged to have excellent methodological quality (bias probability being little), whereas the remaining four received small ratings (immense or indistinct bias risk). Low-quality research supported the assumption that treating periodontal disease had a favorable impact, whereas studies with the best quality provided unambiguous evidence that no such benefit existed. Consistently inconsistent results from low- and best-quality trials were obtained. In high-quality studies, it was observed that the overall rate of preterm delivery periodontal disease treatment significantly lowered the (odds ratio 1.15, 95% confidence interval 0.95–1.40; P = 0.15). In addition, rate of low birth weight infants even after the therapeutics of periodontal disease did not lessen (odds ratio 1.07, 0.85–1.36; P = 0.55), spontaneous abortions/stillbirths (0.79, 0.51–1.22; P = 0.28), or on the whole poor pregnancy outcomes (37 weeks considered as preterm births and/or unprompted abortions/stillbirths) (1.09, 0.91–1.30; P = 0.34). The use of treatment modalities for periodontal disease and other medical procedures can lessen preterm labor. However, treating periodontal disease alone cannot be considered a successful tactic to reduce the likelihood of preterm delivery even if it is not associated with any other medicinal course.
Prevalence of Periodontal Disease in Patients with Polycystic Ovary Syndrome in a Tertiary Centre at Kerala
Authors: Venkataraman Harithrra , Peter Maya Rajan , Sreedhar Sarala , Suresh Reshma , Vyloppillil Rajesh , Sreelakshmi M. R.
Published: February 2023

Background:

Polycystic ovary syndrome (PCOS) is commonly associated with periodontal disease.

Aims:

The aim of the study is to assess the prevalence of periodontal diseases in female patients with PCOS in a tertiary centre at Kerala.

Subjects and Methods:

The study was held between December 2019 and December 2021 where a total of 320 female subjects in the age group of 20–35 years were included and among them 160 were PCOS diagnosed and 160 were healthy controls. Anthropometric and periodontal parameters were recorded and assessed among the groups.

Statistical Analysis Used:

Bivariate analysis between periodontal diseases and other covariant were done using Chi-square test. Those variables which were showing significant level up to 10% were taken to logistic regression model for estimating the adjusted risk for the periodontal diseases in PCOS patients.

Results:

In the PCOS group, 70 subjects (43.7%) were affected by gingivitis, 68 subjects (42.5%) were affected by mild periodontitis and 22 patients (13.7%) were diagnosed with moderate periodontitis. Gingivitis was observed in 153 subjects (95.6%) in the control group and mild periodontitis was only observed in 7 subjects (4.3%) (P < 0.001).

Conclusions:

We can conclude that a dental check-up should be made mandatory in the management protocol of PCOS and the gynaecologist should also play a pivotal role along with the periodontist in the prevention, diagnosis and treatment of periodontal disease in PCOS patients.
Women Faculty in Higher Education
Authors: Venkat Purnima , Sekaran Varalakshmi Chandra , Mayya Shreemathi S. , Ashok Lena , Kamath Veena G.
Published: February 2023

Introduction:

Women's participation in the higher education sector, globally and in India, has seen a steep increase over the past two decades. Despite this increase, women still have several challenges to face in the workplace. The aim of this study was to try and understand the issues faced by women in higher education.

Methods:

This qualitative study uses focus group discussions to open dialog with Indian women who are eligible to occupy/currently occupy administrative positions in higher education to understand their issues, struggles, and realities within the realm of higher education. The study uses the social identity theory to contextualize the experiences of women in higher education and divides the analysis into the broad themes of social categorization, social identification, and social comparison.

Results:

The study finds that women face specific bias in the sector, deal with the dual responsibilities of caregiving and work duties, and also face stereotyping and lack of acceptance in the workplace. Women have mentioned that they need to alter their team management style and leadership styles since, often, men did not seem to be comfortable with being managed by women.

Conclusions:

The study indicates the need for training for all members of higher education on gender issues, especially issues with the management of both home and workplace duties, the need to have mentors and individuals to look up to, and the need for supportive policies for women to be able to succeed in higher education.
Mitral Annulus Disjunction, Annuloaortic Ectasia, and Pseudoaneurysm of Aortomitral Interannular Fibrosa in a 2-Year-Old Child
Authors: Shukla Madhu , Mohan Jagdish Chander
Published: February 2023

Genetically determined deficiency of connective tissue predisposes to the prolapsed mitral valve and an abnormal fibrous annulus including mitral annulus disjunction and dehiscence of aortomitral annular fibrosa. In a more severe phenotype, there may be abnormal aortic tissue, leading to annuloaortic ectasia. This report describes a 2-year-old male child who presented with failure to thrive and was found to have Barlow's syndrome with bileaflet mitral valve prolapse and mitral annulus disjunction, annuloaortic ectasia, and a pseudoaneurysm of interannular fibrosa. The case is reported for its interesting unifying linkage among various defects.
Beliefs About the Effects of Smoking on Corona Virus Disease 2019 and its Impact on the Intention to Quit and Smoking Frequencies Among University Students Smokers in Jakarta, Indonesia
Authors: Nurmansyah Mochamad Iqbal , Suraya Izza , Fauzi Ridhwan , Al-Aufa Badra
Published: February 2023

Introduction:

Several scientific evidence showed that smoking can increase the severity and mortality rate of coronavirus disease 2019 (COVID-19). This indicates that the pandemic is the best time to reduce its frequency or stop the habit, but misinformation that smoking prevents infection has an effect on smokers' behavior. Therefore, this study aims to assess the beliefs about the effects of smoking on COVID-19 as well as to determine their relationship with smoking habits among university student smokers in Jakarta, Indonesia.

Methods:

This study was carried out in three Universities in Jakarta with a total of 198 respondents, who were selected conveniently. Furthermore, independent variables were derived from the Health Belief Model theory, while the dependent variables include quit intention and smoking frequency. Chi-square and ordinal regression analyses were carried out to determine the association between the variables.

Results:

The belief that smoking increases the severity of COVID-19 as well as having the determination to stop the habit, had an effect on the respondents' quit intention. Moreover, perceived barriers, such as feeling anxious (adjusted odds ratio [AOR]: 0.34, 95% confidence interval [CI]: 0.19–0.60) and being exposed to information that the habit prevents COVID-19 severity (AOR: 0.45, 95% CI: 0.01–0.71) were protective factors against the decrease in the number of cigarettes smoked daily.

Conclusion:

Improving digital health literacy, campaigns to clarify the risk of cigarettes, and self-efficacy related to cessation are important efforts to prevent smoking behavior during a pandemic.
UNCERTAINTY ANALYSIS OF MULTI RESIDUE METHODS FOR PESTICIDES IN LETTUCE
Authors: Suman Pooja , Sharma Pushpendra Kumar , Singh Dileep K.
Published: February 2023

Two methods were developed for uncertainty analysis in lettuce using different processing conditions. Methodology I involved analysis through analytical portion sizes of 5, 15, 50 and 150g which were processed at ambient and low temperature processing conditions. 50 and 150g samples recovered a low percentage (68-72%) of pesticides as compared with 5 and 15g (64- 78%) samples. The uncertainty was lowest for 50g samples at ambient temperature and for 15g samples at low temperature processing. 30g analytical portion size was decided to be analyzed through methodology II, resulting in higher recoveries (70-111%) and lower uncertainty (below 11%). The uncertainty and sampling constant determined from internal standard chlorpyrifos was within limit and the pesticide was stable during analysis. The processing of samples at low temperature (i.e., cryogenic milling) was more efficient for the analysis of pesticide residues.