bluuebunny/crossref_metadata_2025 huggingface dataset:
Seeding Activity of Skin Misfolded Tau as a Biomarker for Tauopathies
Authors: Wang Zerui , Wu Ling , Gerasimenko Maria , Gilliland Tricia , Gunzler Steven A. , Donadio Vincenzo , Liguori Rocco , Xu Bin , Zou Wen-Quan
Published: March 2024

Background
Tauopathies are a group of age-related neurodegenerative diseases characterized by the accumulation of pathologically phosphorylated tau protein in the brain, leading to prion-like propagation and aggregation. They include Alzheimer's disease (AD), progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and Pick's disease (PiD). Currently, reliable diagnostic biomarkers that directly reflect the capability of propagation and spreading of misfolded tau aggregates in peripheral tissues and body fluids are lacking.
Methods
We utilized the seed-amplification assay (SAA) employing ultrasensitive real-time quaking-induced conversion (RT-QuIC) to assess the prion-like seeding activity of pathological tau in the skin of cadavers with neuropathologically confirmed tauopathies, including AD, PSP, CBD, and PiD, compared to normal controls.
Results
We found that the skin prion-SAA demonstrated a significantly higher sensitivity (75–80%) and specificity (95–100%) for detecting tauopathy, depending on the tau substrates used. Moreover, increased tau-seeding activity was also observed in biopsy skin samples from living AD and PSP patients examined. Analysis of the end products of skin-tau SAA confirmed that the increased seeding activity was accompanied by the formation of tau aggregates with different physicochemical properties related to two different tau substrates used.
Conclusions
Overall, our study provides proof-of-concept that the skin tau-SAA can differentiate tauopathies from normal controls, suggesting that the seeding activity of misfolded tau in the skin could serve as a diagnostic biomarker for tauopathies.
Identification and sequence analysis of the B2L and F1L genes of the ORFV isolated in Yunnan: epidemiological and evolutionary insights
Authors: xie jiarui , kou meilin , Wang Yinan , Su Xiaohang , Gao Huafeng , Miao Haisheng
Published: March 2024

The primary focus of this investigation was the meticulous examination of the genetic composition and protein structure of the B2L and F1L genes. Notably, specimens were meticulously procured from the oral cavities of infected goats. Subsequent to verification through polymerase chain reaction (PCR), the virus was successfully cultured in goat testis cells. The designated ORFV strains were denoted as ORFV/goat/YNSLi/China/2021/Yunnan,ORFV/goat/YNSLi/China/2023/Yunnan,ORFV/goat/YNYLn/China/2022/Yunnan,and ORFV/goat/YNTJe/China/2023/Yunnan. The genetic data pertaining to the core genes (B2L, F1L) were meticulously scrutinized to elucidate their epidemiological and evolutionary attributes. Analysis of the B2L gene sequences revealed that all four strains were classified within cluster I of group I, with discernible variations in sequences across the temporal spectrum. Conversely, inspection of the F1L gene sequences unveiled that YNSLi/2023 and YNTJe/2023 were positioned in cluster I of group I, YNSLi/2021 resided in cluster III of group I, and YNYLn/2022 was allocated to cluster IV. The distinctive Yunnan ORFV strains exhibited noteworthy characteristics, including gene rearrangements during the outbreak. Examination of the protein structures showcased variances in hydrophobicity and stability in comparison to other strains. While similarities were noted in hydrophilic flexibility, antigenic index, and surface accessibility, discrepancies in amino acids were observed to influence protein structure. Projections derived from the analysis of the B2L and F1L genes suggested the absence of signal peptides and transmembrane domains. This comprehensive study contributes significantly to the comprehension of ORFV transmission and evolution, thereby furnishing invaluable insights for the formulation of preventive and control strategies within Yunnan Province.
Anomalous coherent and dissipative coupling in dual photon-magnon hybrid resonators: effect of relative split-gap orientation
Authors: Jeon Haechan , Kim Bojong , Kim Junyoung , Bhoi Biswanath , Kim Sang-Koog
Published: March 2024

We explored the distinctive behavior of coherent and dissipative photon-magnon coupling (PMC) in dual hybrid resonators, each incorporating an Inverted Split-Ring Resonator (ISRR) paired with a Yttrium Iron Garnet (YIG) film, positioned in close proximity but with varying relative split-gap orientations. These orientations led to notable shifts in the dispersion spectra, characterized by level repulsion and attraction, signaling coherent and dissipative coupling, respectively, in single ISRR/YIG hybrids at certain orientations. Through analytical modeling, we determined that the observed shifts in coupling types are primarily due to the effect of photon-photon (ISRR-ISRR) interactions altering the phase difference between the coupled ISRR and magnon modes. Our findings highlight that precise manipulation of the relative split-gap orientations in the ISRR resonators enables controlled coherent and dissipative coupling within planar PMC systems. This capability opens new avenues for applications in quantum information technologies and quantum materials.
Milk thistle (Silybum marianum, Asteraceae), recorded for the first as invasive weed species in Addis Ababa city, Ethiopia
Authors: Kassie Weldesenbet Beze
Published: March 2024

Milk thistle, Silybum marianum was observed in road sides, urban green areas and wasted places of Addis Abeba city, Ethiopia since, 2020. This study aimed to determine the current distribution status of the weed in urban green areas of the city to provide information for future management activities. Weed surveys were conducted across 42 urban green sites located in Yeka, Lemi Kura, Bole, Nifas Silk-Lafto, Kolfie Keraniyo, Akaky Kality and Gullele sub-cities during the main rainy season from June to September 2023. The urban green areas were selected by using purposive sampling techniques. Field observations confirmed that Silybum marianum can invade and colonize wide habitats and is a highly competitive invasive weed to other important native plant species. High weed density rates and dense stands of weeds were recorded in the 34 urban green areas. The present study gives an accurate assessment and understanding of Silybum marianum, which is further important for their scientific management and utilization by means of fast integrated weed management options such as mowing/tilling, weeding before the plant goes to seed, cutting (stems and/or seed heads), and burning (collected plant parts and/or seed heads) into a prepared burrow were done to minimize the spreading of the weed and its ecological impacts.
Ultrasound evaluation of kidney and liver involvement in Bardet-Biedl syndrome
Authors: Cetiner Metin , Finkelberg Ilja , Schiepek Felix , Pape Lars , Hirtz Raphael , Büscher Anja
Published: March 2024

Background
Bardet-Biedl syndrome (BBS) is a rare autosomal-recessive ciliopathy with pathogenic variants in at least 26 BBS genes. It affects multiple organs including kidney and liver, however, organ involvement differs widely regarding extent and time of first manifestation. Structural renal anomalies are an early feature with a frequency of > 50% and end-stage kidney disease (ESKD) cumulates to 25% in adolescence. Early-onset hyperphagia-associated obesity is another major symptom and contributes to liver pathology, presenting as steatosis/fibrosis. Aim of this study is the evaluation of high-end ultrasound (US) technologies including shear wave elastography (SWE), dispersion (SWD), and attenuation imaging (ATI) in BBS patients regarding their potential to discriminate liver and kidney tissue pathology at an early stage.
Materials and Methods
Patients with genetically proven BBS were recruited from the University Children’s Hospital of Essen and from BBS patient days hosted in Germany. Acute illness was an exclusion criterion. Clinical and laboratory data were extracted from patients’ digital records or medical letters.
Results
49 BBS patients (24/49 male; aged 1.1–51.0 years, mean 17.8 years) were included in the study. Mean body weight (SDS 2.13 ± 1.33) and BMI (SDS 2.64 ± 1.18) were increased. Structural kidney abnormalities (dysplasia, cysts) were present in 75% (36/48) and persistent fetal lobulation in 44% (21/48). Renal function was impaired in 27% (13/49) and 3/13 had ESKD (kidney transplantation (n = 2), hemodialysis (n = 1)). Elevation of liver enzymes was detected in 38% (16/42). In 51% (25/49) ATI of liver tissue was increased, indicating hepatic steatosis, and correlated with BMI SDS, liver size, and enzymes. SWE was elevated in 61% (30/49) suggesting hepatic fibrosis and was associated with BMI and GGT. Patients with pathogenic variants in BBS10 showed a tendency towards higher ATI and reduced GFR, and had significantly higher BMI SDS.
Conclusions
We detected abnormalities of the kidney and liver in a higher percentage of BBS patients than previously reported, indicating a high sensitivity of the evaluated US applications. ATI detected liver pathology early (partially prior to liver enzymes) and revealed differences related to the affected genes. Evidence of tissue pathology at an early stage may improve diagnostics and the evaluation of therapeutic approaches.
How histopathological diagnosis interacts with kidney ultrasound parameters to predict glomerular filtration rate
Authors: Andrulli Simeone , Gigante A , Rossini Michele , D'Angiò Pierluigi , Vischini Gisella , Lucchetta Franca , Aucella Filippo , Valsecchi Giovanni , Infante Barbara , Vario Maria Giovanna , Giannese Domenico , Granata Antonio , Moggia Elisabetta , Gembillo Guido , Cianci Rosario , Bonomini Mario , Manenti Flavia , Lazzarin Roberta , Renzo Brigida Di , Zanchelli Fulvia , Garozzo Maurizio , Manes Massimo , Battaglia Yuri , Sciri Raffaella , De Fabritiis Marco , Quaglia Marco , Cavoli Gioacchino Li , Gintoli Enrica , Conte Maria Maddalena , Borzumati Maurizio , Benozzi Luisa , Pasquariello Giovanna , Andrulli Giovanni , Leoni Marco , Seminara Giuseppe , Corbari Valentina , Sabiu Gianmarco , Maggio Arcangelo Di , Pollastro Rosa Maria , Gesualdo Loreto
Published: March 2024

Background eGFR evaluation is a pivotal staging step in patients with chronic kidney disease (CKD), and renal ultrasound plays an important role in diagnosis, prognosis and progression of CKD. The role of the interaction between histopathological diagnosis and ultrasound parameters in the eGFR determination has not been fully investigated yet.Methods The study examined the results of native kidney biopsies performed in 48 Italian centers between 2012 and 2020. The primary goal was if and how the histopathological diagnosis influences the relationship between eGFR and ultrasound parameters.Results After exclusion of children, patients with acute kidney injury and patients without measure of kidney length or parenchymal thickness, 2795 patients have been selected for analysis. The median values were 52 years for patient age, 11 cm for bipolar kidney diameter, 16 mm for parenchymal thickness, 2.5 g/day for proteinuria and 70 ml/min/1.73 m2 for eGFR. The bipolar kidney diameter and the parenchymal thickness predict eGFR values (R square 0.064). Diabetes and proteinuria were associated with a consistent reduction of eGFR, improving the adjusted R square up to 0.100. Addition of histopathological diagnosis in the model increased the adjusted R square to 0.216. There is a significant interaction between histopathological diagnosis and longitudinal kidney diameter (P 0.006).Conclusions Renal bipolar length and parenchymal thickness are directly related with eGFR. The magnitude of proteinuria and histopathological kidney diagnosis increased the prediction of eGFR. The association between the kidney length and the level of eGFR depends on the nature of the kidney disease.
Neural Network for Asymptotic Dependence/ Independence Classification: A Series of Experiments
Authors: Wixson Troy P. , Cooley Daniel
Published: March 2024

An early choice in the modeling of multivariate extremes is to infer whether the data are asymptotically dependent (AD) or asymptotically independent (AI). We perform a series of experiments to determine whether a convolutional neural network can reliably distinguish between these asymptotically defined regimes in the finite sample bivariate case. Along the way we develop a new classification tool for practitioners which we call \texttt{nnadic} as it is a Neural Network for Asymptotic Dependence/ Independence Classification. This tool accurately classifies 95% of test datasets and is robust to a wide range of sample sizes. The datasets which we are unable to correctly classify tend to either be nearly exactly independent or exhibit near perfect dependence, which are boundary cases for both the AD and AI models used for training.
Datasets for Large Language Models: A Comprehensive Survey
Authors: Liu Yang , Cao Jiahuan , Liu Chongyu , Ding Kai , Jin Lianwen
Published: March 2024

This paper embarks on an exploration into the Large Language Model (LLM) datasets, which play a crucial role in the remarkable advancements of LLMs. The datasets serve as the foundational infrastructure analogous to a root system that sustains and nurtures the development of LLMs. Consequently, examination of these datasets emerges as a critical topic in research. In order to address the current lack of a comprehensive overview and thorough analysis of LLM datasets, and to gain insights into their current status and future trends, this survey consolidates and categorizes the fundamental aspects of LLM datasets from five perspectives: (1) Pre-training Corpora; (2) Instruction Fine-tuning Datasets; (3) Preference Datasets; (4) Evaluation Datasets; (5) Traditional Natural Language Processing (NLP) Datasets. The survey sheds light on the prevailing challenges and points out potential avenues for future investigation. Additionally, a comprehensive review of the existing available dataset resources is also provided, including statistics from 444 datasets, covering 8 language categories and spanning 32 domains. Information from 20 dimensions is incorporated into the dataset statistics. The total data size surveyed surpasses 774.5 TB for pre-training corpora and 700M instances for other datasets. We aim to present the entire landscape of LLM text datasets, serving as a comprehensive reference for researchers in this field and contributing to future studies. Related resources are available at: \href{https://github.com/lmmlzn/Awesome-LLMs-Datasets}{https://github.com/lmmlzn/Awesome-LLMs-Datasets}.
An Intelligent Model and Simulation of High Voltage Transmission Line Protection Using Time Overcurrent Relay Optimization Settings
Authors: BONIFACE NTAMBARA , Sitati Simiyu S. , Byiringiro Jean Bosco , Wambua Paul M.
Published: March 2024

The novel method based on optimal overcurrent relay settings and coordination for effective substation relays in interconnected power systems was designed and developed. In this paper, the feeder impedance equivalences, phase-to-phase fault currents, current settings of 110kV incoming and 15kV outgoing feeders, and operating times for relay characteristics (standard, very, and extremely inverse of overcurrent relay) of the power network were computed and determined. The maximum fault current of the interconnected power grids was considered. The network MVA short circuit was considered with both positive and negative sequence impedance of the feeder. The power system parameters like X/R ratio, current transformer (CT) ratio, transmission line length, positive & zero-sequence resistances, positive & zero-sequence inductances, full load current, line capacity, CT ratio for outgoing feeders, grid frequency, and real power were also considered and deployed in the power network. To ensure safety, reliable, and rapid operation of overcurrent relays, settings such as pickup value, time setting multiplier (TMS) of 0.05sec, and overcurrent relay (OCR) characteristics were carefully considered. The selection and determination of OCR characteristics were taken into account by calculating the fault current levels of each fault location percentage based on feeder impedance, turn CT ratio, and pickup values. The results proved that the OCRs coordination interval time to fastest clear faults was between 0.0927 sec-0.062 sec, 0.0949 sec-0.0720 sec, and 0.0764 sec-0.0661 sec for extremely, very, and standard inverse relays, respectively.
Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma
Authors: Smith Nicola , Reddin Ian , Policelli Paige , Oh Sunwoo , Buisson Rémi , Zainal Nur , Howes Emma , Jenkins Benjamin , Tracy Ian , Sharpe Benjamin , Amendra Damian , Hanley Christopher , King Emma , Thomas Gareth , Edmond Mark , Ali Simak , Zheng Ke , Egawa Nagayasau , Doorbar John , Carpenter Michael , Harris Reuben , Rao Anjali , Mahadevan Sangeetha , Fenton Tim
Published: March 2024

Two APOBEC (apolipoprotein-B mRNA editing enzyme catalytic polypeptide-like) DNA cytosine deaminase enzymes (APOBEC3A and APOBEC3B) generate somatic mutations in cancer, driving tumour development and drug resistance. Here we used single cell RNA sequencing to study APOBEC3A and APOBEC3B expression in healthy and malignant mucosal epithelia, validating key observations with immunohistochemistry, spatial transcriptomics and functional experiments. Whereas APOBEC3B is expressed in keratinocytes entering mitosis, we show that APOBEC3A expression is confined largely to terminally differentiating cells and requires Grainyhead-like transcription factor 3 (GRHL3). Thus, in normal tissue, neither deaminase appears to be expressed at high levels during DNA replication, the cell cycle stage associated with APOBEC-mediated mutagenesis. In contrast, we show that in squamous cell carcinoma tissues, there is expansion of GRHL3 expression and activity to a subset of cells undergoing DNA replication and concomitant extension of APOBEC3A expression to proliferating cells. These findings indicate a mechanism for acquisition of APOBEC3A mutagenic activity in tumours.
Observations of the Polarized Solar Corona During the Annular Eclipse of October 14, 2023
Authors: Seaton Daniel B. , Caspi Amir , Alzate Nathalia , Davis Sarah J. , DeForest Craig , Erickson Nicholas F. , Kovac Sarah A. , DeForest Alec R. , Patel Ritesh , Osterman Steven N. , Tosolini Anna , Kooten Samuel J. Van , West Matthew J.
Published: March 2024

We present results of a dual eclipse expedition to observe the solar corona from two sites during the annular solar eclipse of 2023 October 14, using a novel coronagraph designed to be accessible for amateurs and students to build and deploy. The coronagraph CATEcor builds on the standardized eclipse observing equipment developed for the Citizen CATE 2024 experiment. The observing sites were selected for likelihood of clear observations, for historic relevance (near the Climax site in the Colorado Rocky Mountains), and for centrality to the annular eclipse path (atop Sandia Peak above Albuquerque, New Mexico). The novel portion of CATEcor is an external occulter assembly that slips over the front of a conventional dioptric telescope, forming a \textit{shaded-truss} externally occulted coronagraph. CATEcor is specifically designed to be easily constructed in a garage or ''makerspace'' environment. We successfully observed the solar corona to an altitude of approximately 2.25 RSun during the annular phases of the eclipse.
Resveratrol-Based 5-Membered Carbonate (Res-TC) Resins: Synthesis and Curing with Trioxyethylene Diamine (TODA)
Authors: Matsumoto Kozo , Yamashita Iku , Watanabe Tatsuki
Published: March 2024

Novel bio-based trifunctional 5-membered cyclic carbonate (Res-TC) resins were synthesized via glycidyl etheration of resveratrol and successive insertion of carbon dioxide to the epoxy groups. The resins were thermally cured with trioxyethylene diamine (TODA), and cured Res-TC/TODA films were prepared. Thermal properties of the cured material were examined by differential scanning calorimetry (DSC) and thermal gravimetric analysis (TGA). The glass transition temperature (Tg) and 5% weight loss temperature (Td5) of the cured Res-TC/TODA were determined to be 15.4oC and 224oC, respectively. These results indicated that the cured material was rubbery at room temperature and easily decomposable at elevated temperature. The elastic modulus, tensile strength, and elongation at break were 850 MPa, 38.3 MPa, and 0.068, respectively, which shows that the cured material was tough and flexible. Shear adhesion strength of the cured materials toward stainless substrates was estimated at 10.8 MPa, indicating their high applicability to adhesives. Examination of the enzymatic degradation of the cured materials revealed their potential degradability by enzymes such as lipase and protease.
Advancing Phase Change Materials (PCM) Technology: Research, Development, and Optimization
Authors: Proca Andrei
Published: March 2024

Phase Change Materials (PCMs) play a pivotal role in various heating and refrigeration applications by leveraging the latent heat exchange during phase transitions. However, recent demands for PCMs with higher melting temperatures, superior mechanical properties, enhanced thermal conductivity, and reduced reactivity to environmental conditions have necessitated a focused research effort. Our team embarked on a systematic exploration of alloy compositions theoretically suited to meet these stringent requirements. Employing advanced techniques in material science, we conducted comprehensive analyses to identify promising candidates with the desired attributes. Subsequent experimental phases involved the fabrication and thorough testing of these alloys under controlled conditions. Through meticulous evaluation of their performance characteristics, including thermal behavior, mechanical strength, and environmental stability, we aimed to pinpoint the most suitable material for PCM applications. Our research endeavors not only contribute to the advancement of PCM technology but also hold significant implications for energy efficiency and sustainability in diverse industrial sectors.
Prevalence of Metabolic Syndrome among middle-aged patients and its association with chronic kidney disease: A Cross-sectional study
Authors: M Shankar Ganesh , S Aravindhan , S Satheesh
Published: March 2024

Background
Previous surveys suggest that obesity, hypertension, and diabetes mellitus may be positively related to the development of chronic kidney disease (CKD). However, this association might be altered by metabolic syndrome. Chronic kidney disease has become a worldwide health problem among aging populations. Hence, epidemiological information on middle-aged patients with metabolic syndrome is still lacking.
Objectives
The study aimed to assess the prevalence of metabolic syndrome among middle-aged patients and its association with chronic kidney disease.
Methodology:
The hospital-based cross-sectional study was carried out on 317 participants aged 40–59 years. All participants received a standardized personal interview, including a structured questionnaire, anthropometric measurements, and blood samples collected for laboratory testing. Metabolic syndrome was identified based on the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III). The estimated glomerular filtration rate (eGFR) was calculated by using the Cockroft-Gault formula, which in turn is utilized to predict the stages of chronic kidney disease based on the eGFR range based on NKF-KDOQI.
Result and discussion:
We investigated the association between metabolic syndrome and chronic kidney disease (CKD) in 317 participants aged 40-59 years. We found that metabolic syndrome was prevalent in more than half of the participants (54.2%) and increased with the worsening of CKD stages. We also identified waist circumference, fasting blood sugar, and triglycerides as significant metabolic factors associated with CKD. Furthermore, we observed that longer durations of diabetes mellitus and hypertension, especially when combined, increased the risk of CKD.
Conclusion:
Our findings suggest that metabolic syndrome is a major contributor to CKD and that early detection and management of metabolic factors are essential to prevent kidney damage.
Telehealth Consultation for Malaysian Citizens’ Willingness to Pay Assessed by the Double-Bounded Dichotomous Choice Method
Authors:   Graduate School of Health Sciences, School of Medicine, Hokkaido University, Hokkaido, Japan, Mey Mey Tan , Ogasawara Katsuhiko ,   Graduate School of Health Sciences, School of Medicine, Hokkaido University, Hokkaido, Japan
Published: March 2024

Background: Re-envisioning healthcare in technology tools includes robust utilisation of telehealth, improvement in access, quality, care efficiencies and cost-effectiveness of healthcare services. In reality, the technology’s potential to transform healthcare may be limited by the ability to pay for it. This study aims to estimate Malaysian citizens’ willingness to pay (WTP) for telehealth consultations and determine the factors contributing to it. This is vital to inform decision-making about expansion, preferences and deployment of a pricing strategy for telehealth services. Methods: A random sample of 220 adult Malaysians was surveyed using social network services (SNS). Three different WTP bid arrays were identified and each respondent received a randomly drawn bid price. The WTP fee for using the telehealth consultation for 30 min was measured and estimated using a Double-Bounded Dichotomous Choice (DBDC) and the Random Utility Logit Model. Result: The median WTP was estimated to be RM58 (JPY2,198), RM78 (JPY2,956) for 132 respondents’ willingness to use telehealth consultation and RM26 (JPY985) for 51 respondents who were unwilling. Further analysis found that WTP is correlated with the perception and willingness of the respondents to use it. Conclusion: Despite most respondents being willing to pay for telehealth consultations, sociodemographic characteristics and affordability influenced the process of making decisions about WTP for telehealth consultation. This finding suggests that the private sector can play a crucial role in the deployment of telehealth. However, there may be a need to consider affordability and how to increase access and use of telehealth services.
A budai tanítóképző tanárait és altisztjét érintő igazolási, B-listázási és népbírósági eljárások (I. rész)
Authors: Donáth Péter
Published: March 2024

A magyarországi radikális rendszerváltozások során 1919-1921-ben majd 1945-1948-ban sokszor előfordult, hogy az előző rezsimben prominens, vezető állású pedagógusokat igazolási eljárások, B-listázások, büntető bírósági eljárások során megbélyegezték, pályájukról eltávolították. Ez részben az új hatalom, részben az illető kollégáinak kezdeményezésére történt. A Neveléstudomány két egymást követő számában közlésre kerülő dokumentatív elbeszélés a budai képző tanárai és tanítói ellen 1945-1946-ban folytatott eljárásokat tekinti át. Az első részben Padányi-Frank Antal budai tanítóképző igazgatónak, a képzős tanárok szakmai szervezete elnökének eltávolítását, megveretését, fogságait, elítélésének folyamatát idézi fel. Az első rész az előzmények ismertetése mellett az igazolási eljárás, rendőrségi feljelentés, a fizikai bántalmazás és fogságba vetés a népügyészségi és népbírósági eljárás dokumentumaival, a vád is védelem által felsorakoztatott tanúk állításaival, a vád bizonyítékaival foglalkozik. Mindkét rész nagy figyelmet szentel a folyamat mechanizmusaira, s a benne részt vevő pedagógusok, diákok szerepére, s a régi rendszer kedvencéből meghurcolt vádlottá lett igazgató úr drámájára.
Munkahelyi kihívások és erőforrások Kárpát-medencei oktatók körében: egy interjús kutatás eredményei
Authors: Kovács Klára , Dobay Beáta , Halasi Szabolcs , Pinczés Tamás , Tódor Imre
Published: March 2024

A felsőoktatás mint munkahely, illetve az oktatók helyzete jelentősen megváltozott az elmúlt évtizedekben. A felsőoktatás expanziója, diverzifikálódása, szolgáltató irányba történő elmozdulása következtében az oktatóknak többféle és újfajta szerepkörnek kell megfelelniük, így munkájuk során számos stresszforrásnak vannak kitéve. Tanulmányunkban a Közép-Kelet-Európai (KKE) oktatók egészségét és jóllétét befolyásoló munkahelyi tényezőket vizsgáljuk. Fő kérdésünk, hogy milyen nehézségekkel kell megküzdeniük a régió oktatóinak munkájuk során, s mik azok az erőforrások, melyek hozzájárulnak jóllétükhöz. További kérdéseink, hogy melyek azok az intézményi tényezők, melyek javít(hatják) vagy éppen rontják jóllétüket, illetve egyéni szinten milyen módon képesek megküzdeni a munkahely okozta stresszel. E kérdések vizsgálatához elméleti háttérként a munkakövetelmények és erőforrások elméletét (JD-R theory) alkalmaztuk, s fókuszcsoportos interjús kutatást végeztünk magyarországi, illetve határon túli kisebbségi magyar intézményekben dolgozó oktatókkal (N=41). Eredményeink szerint a legfontosabb munkahelyi nehézségek, kihívások és erőforrások az oktatói szerepkörökhöz, a munkaterheléshez, az interperszonális kapcsolatokhoz, a menedzsment támogatásához és az infrastrukturális feltételekhez kapcsolódnak.
Place of Women in Environmental Management and Sustainability in Nigeria
Authors: Ezugwu Umezurike J. , Maduka Enyimba , Etta Emmanuel E. , Ekanem Samuel Aloysius , Egaga Ushie Thomas
Published: March 2024

In this essay, we contend that the relationship between human society and physical environment is not gender neutral, as men and women are treated inequitably. There exists an inequitable binary structure between the two polar values, as human society often exploits and degrades the environment, and women are undermined in various occasions. The role of women is undermined in environmental management and monitoring. Our strategy in dealing with this issue of negligence would be to expose the misconception that women have little or nothing to contribute in environmental management beside biological reproductive roles, and activities such as cooking, washing, fetching firewood and nursing of children. We will also show the negative impacts of these forcefully assigned female duties on the climate, and how this leads to pollution, which in turn, obstructs the biospheres (plant and animal species). Using the principle of complementarity, the paper insists on the need to eradicate all socio-culturally perceived superlative attributes of distinction between human society and environment or masculinity and femininity. The paper calls for mainstreaming of gender perspective, expansion of women’s opportunities and participation in environmental management, at all levels, for environmental sustainability.
Research Outlines of the Sustainable Profile of Believers in Croatia
Authors: Brstilo Lovrić Ivana , Brgles Miriam Mary , Mravunac Damir
Published: March 2024

The topic of this paper are sustainable habits and attitudes of the religious population in Croatia regarding the Encyclical Letter Laudato Si’. Empirical work is based on CRO Laudato Si' project using survey method on a non-probabilistic sample of the religious population in Croatia, which in this paper are operationalized as active and occasional believers according to their regularity of attending religious ceremonies (N=1305). The analysis showed that active believers have a more pronounced sustainable profile (as they throw away less food, separate waste more, show greater readiness for saving water, electrical energy and have a more pronounced critical attitude about the need for greater application of the Laudato Si' within the Church and society) than the occasional believers. Given the nonrepresentative sample, the presented data cannot be generalized to the religious population in Croatia, shaping its fundamental contribution in stimulating future scientific analyses and reflections on the Church's relationship with religious practices, and emphasizing active believers as potential social leaders of sustainable lifestyles. Therefore, the sustainable habits of the surveyed believers represent a relational good and serve as the basis for building a culture of moderation that respects key principles of Catholic Social Teaching. In that perspective, we conclude that it is important for the Church to speak more often about the socio-environmental crisis and encourage strong responses to the crisis at all social levels, from households and families to the macro level.
Efecto del método de encordado sobre el crecimiento y la perdida de mejillones (Mytilus platensis D’ORB.) en cultivos suspendidos.
Authors: Zaixso Héctor E. , Lizarralde Zulma I.
Published: March 2024

En este trabajo se estudia comparadamente el crecimiento y la pérdida de individuos de mejillones (Mytilus platensis d’Orb.) en cuerdas confeccionadas con las técnicas española y francesa de encordado para cultivos suspendidos. Los juveniles utilizados en la misma fueron obtenidos de colectores artificiales y las cuerdas de cultivo experimentales fueron suspendidas en el golfo Nuevo (Chubut, Argentina: 42° 46' S y 64° 59" W), en un sistema de «long-line» de media agua por un período de 15 meses (marzo de 1988 a junio de 1989). Los datos fueron estudiados a través de analisis de la covarianza y de tablas de contingencia a través de la prueba G. La longitud máxima promedio de animales, obtenida en los encordados armados según el método español fue significativamente mayor que el de los encordados franceses, a lo largo de todo el ciclo de cultivo. Al principio de la experiencia las pérdidas fueron significativamente mayores en los encordados españoles, se igualaron hacia el mes duodécimo de cultivo y finalmente fueron significativamente mayores en los encordados confeccionados con la técnica francesa. La biomasa húmeda de carne de mejillones por metro de cuerda de cultivo se incrementa en ambos métodos de encordado hasta el mes duodécimo y disminuye en el décimoquinto mes; esta biomasa es siempre mayor en los encordados españoles. La biomasa cosechable por metro de cuerda inicial de cría depende de las características del desdoble, siendo en la presente experiencia máxima en el duodécimo mes de cultivo y mayor en los encordados franceses.
El uso de redes neuronales artificiales en la predicción de desembarques: un ejemplo de aplicación en pesquerías artesa00nales.
Authors: Abades Sebastián R.
Published: March 2024

Se implemento una red neuronal artificial para ilustrar la utilidad de esta técnica en la predicción de desembarques, utilizando como ejemplo de aplicación a tres recursos bentónicos comercialmente explotados: navajuela, huepo y piure. La red neuronal artificial consiste en un tipo de regresión múltiple muy sofisticada en su operatoria, capaz de captar relaciones estructurales de distinta naturaleza entre las variables predictoras y la(s) de respuesta. La red neuronal "aprende" sobre los diversos escenarios a los que ha sido expuesta durante una fase de entrenamiento inicial, con la consecuente capacidad de generalizar y proponer predicciones muy ajustadas a la realidad. Se trabajó en base al algoritmo de retropropagación, con el cual es posible supervisar el proceso de aprendizaje de la red neuronal. Las predicciones de los desembarques obtenidas fueron altamente consistentes con las observadas, tanto en la escala de resolución mensual como en la anual. Se discute sobre el potencial de esta metodología como complemento de las evaluaciones de stock, en particular para situaciones donde las reglas de ensamblaje de un sistema de interés son desconocidas o muy complejas.
Strategic-Competitiveness for Socio-Economic Development: Unlocking the Potential of Gorontalo Province in the Context of the Nusantara Capital Integrated Development (IKN)
Authors: Humalanggi Mahyudin , Lantapon Nancy Noviana , Butolo Ivana , Saksono Herie
Published: March 2024

The development of the Capital City of Nusantara (IKN) in East Kalimantan Province was an important turning point in Indonesia's development model. As one of its close neighbors, Gorontalo Province has great potential to contribute to developing IKN. Cohesion between Gorontalo Province and IKN is key to achieving its socio-economic development goals. However, Gorontalo Province still faces problems in economic development, public services, and MSMEs, including slow local economic development, inadequate infrastructure, low community competitiveness, high levels of poverty, and socio-economic problems. This study aims to analyze the problems and potential of the Gorontalo Provincial Government in its contribution and cohesion to the socio-economic development of IKN. Through a well-being methodology (WM) approach combining qualitative and quantitative approaches, three main dimensions are emphasized: perception, participation and community acceptability of competitive strategies to provide a holistic and participatory understanding of welfare aspects. The study found that the people of Gorontalo have a positive view of IKN, with the hope that the Gorontalo Provincial Government can strengthen its contribution through improving the quality of human resources, infrastructure and economic competitiveness to support the socio-economic development of IKN. Interestingly, most respondents were generation Z. This shows that most of Gorontalo's young generation were involved in this research. In essence, the Gorontalo Provincial Government faces challenges in its contribution and cohesion to the socio-economic development of IKN, with low levels of public participation and a lack of public understanding of the benefits of development. Therefore, intensive efforts are needed in socialization, education, and public involvement to increase participation and strengthen the IKN development process. The Gorontalo Provincial Government is advised to design an integrated competitive strategy, focusing on increasing public perception through socialization, building trust, fostering public participation, and increasing the acceptability of IKN development.
XXV Asamblea general de miembros activos :informe anual 2015
Authors:   Corporación Colombiana de Investigación Agropecuaria, Mosquera (Colombia)
Published: March 2024

En cumplimiento de la misi6n de Corpoica, en su rol como Motor del SNCTA, hizo parte del grupo que apoya a la Misión Rural para la transformaci6n del Campo en materia de Ciencia, Tecnología e lnnavaci6n, elaboranda el diagn6stico sectorial1 y la propuesta de la estrategia para la innavaci6n agropecuaria2 • Este trabaja, sent6 las bases para queen el 2015 y par interes de Colciencias en articulaci6n con el Ministeria de Agricultura y Desarrolla Rural, Carpoica se diera a la tarea de coordinar la participaci6n de las diversas actares del Sistema Nacional de Ciencia y Tecnologia Agroindustrial (SNCTA) para formular el Plan Estrategico de Ciencia, Tecnología e lnnovaci6n del Sector Agroindustrial, (Agrkola, Pecuario, Foresta!, Pesquero y Agroindustrial) PECTIA 2016- 2026. En cumplimiento de la misi6n de Corpoica, en su rol como Motor del SNCTA, hizo parte del grupo que apoyo a la Misión Rural para la transformaci6n del Campo en materia de Ciencia, Tecnología e innovación, elaborando el diagnóstico sectorial y la propuesta de la estrategia para la innovación agropecuaria sent6 las bases para que en el 2015 y par interés de Colciencias en articulación con el Ministerio de Agricultura y Desarrolla Rural, Corpoica se diera a la tarea de coordinar la participación de las diversas actores del Sistema Nacional de Ciencia y Tecnología Agroindustrial (SNCTA) para formular el Plan Estratégico de Ciencia, Tecnología e innovación del Sector Agroindustrial, (Agrícola, Pecuario, Forestal, Pesquero y Agroindustrial) PECTIA 2016- 2026.
Caracterización de ácidos grasos en carne de bovinos cebados en un sistema de producción Silvopastoril en el Valle del Sinú
Authors: Mestra Vargas Lorena I. , Burgos Paz William O. , Barragán Hernández Wilson A. , Medina Herrera Diego A. , Mejía Luquez Jorge A.
Published: March 2024

La carne es considerada un alimento de alto valor nutricional debido a sus concentraciones de ácidos grasos poliinsaturados (PUFA) y ácido linoleico conjugado (CLA), los cuales son esenciales para el mantenimiento de la salud y prevención de enfermedades. El manejo de las fuentes de alimentación de animales durante su crecimiento puede orientarse en favor de mejores per les de ácidos grasos en la carne.
A Content Analysis of Indoor Tanning Twitter Chatter During COVID-19 Shutdowns: Cross-Sectional Qualitative Study
Authors: Groshon Laurie , Waring Molly E , Blashill Aaron J , Dean Kristen , Bankwalla Sanaya , Palmer Lindsay , Pagoto Sherry
Published: March 2024

Background

Indoor tanning is a preventable risk factor for skin cancer. Statewide shutdowns during the COVID-19 pandemic resulted in temporary closures of tanning businesses. Little is known about how tanners reacted to losing access to tanning businesses.

Objective

This study aimed to analyze Twitter (subsequently rebranded as X) chatter about indoor tanning during the statewide pandemic shutdowns.

Methods

We collected tweets from March 15 to April 30, 2020, and performed a directed content analysis of a random sample of 20% (1165/5811) of tweets from each week. The 2 coders independently rated themes (κ=0.67-1.0; 94%-100% agreement).

Results

About half (589/1165, 50.6%) of tweets were by people unlikely to indoor tan, and most of these mocked tanners or the act of tanning (562/589, 94.9%). A total of 34% (402/1165) of tweets were posted by users likely to indoor tan, and most of these (260/402, 64.7%) mentioned missing tanning beds, often citing appearance- or mood-related reasons or withdrawal. Some tweets by tanners expressed a desire to purchase or use home tanning beds (90/402, 22%), while only 3.9% (16/402) mentioned tanning alternatives (eg, self-tanner). Very few tweets (29/1165, 2.5%) were public health messages about the dangers of indoor tanning.

Conclusions

Findings revealed that during statewide shutdowns, half of the tweets about indoor tanning were mocking tanning bed users and the tanned look, while about one-third were indoor tanners reacting to their inability to access tanning beds. Future work is needed to understand emerging trends in tanning post pandemic.
A case of co-infection with head lice and varicella in a child: considerations for rational management
Authors: Shvaratska O.V. , Mavrutenkov V.V. , Svyatenko T.V. , Yakunina O.M.
Published: March 2024

Pediculosis and varicella, common in children, typically pose no significant diagnostic or treatment challenges. However, the ongoing full-scale war in Ukraine has led to severe humanitarian consequences, including mass migration and health care infrastructure damage. Under such conditions, standard treatment modalities, including isolation and hygiene measures, may be impracticable. These challenges underscore the need for adapting patient management strategies to crisis conditions. We report a case of a previously well 10-year-old female, presenting with pediculosis capitis and varicella co-infection, complicated by folliculitis. Pediculosis had been detected by the parents one week before the onset of varicella, and they self-administered a topical anti-pediculosis agent based on clearol and dimethicone once. On the 12th day of varicella infection, we found purulent rash elements on the scalp, severe pruritus, and presence of lice eggs and nits. Considering the evidence of folliculitis on the scalp, which complicated the use of external pediculicides and hygienic procedures, the case necessitated a tailored treatment approach. This included oral cefuroxime for bacterial superinfection, and two doses of oral ivermectin for pediculosis 200 mcg/kg one week apart, along with chloropyramine hydrochloride for pruritus management. The strategy resulted in elimination of head lice infestation with no adverse events. This case illustrates the critical need for updated clinical protocols and health care provider education on optimal treatment practices, especially in crisis contexts. The coexistence of varicella with a pediculosis infection precipitated a secondary bacterial infection requiring systemic antibacterial treatment. Clinical research provides evidence of oral ivermectin effectiveness in pediculosis treatment when topical pediculicides cannot be utilized. To mitigate varicella complications and control epidemic processes, integrating varicella vaccination into the national immunization schedule is recommended. Moreover, for cases with varicella and ectoparasitic infections, systemic treatment with antiviral and antiparasitic agents like acyclovir and ivermectin should be considered to minimize the risk of superinfection. The registration of oral ivermectin for pediculosis treatment by state health authorities is advocated to formalize its use in clinical practice.
Transportation of Freight along the Trans-Mongolian Railway and Planning for the Rolling Stock Park
Authors: Nergui Munkhdul , Ulzii-Ochir Nomintsetseg
Published: March 2024

The main purpose of this study is to forecast the general trend of the country’s economic development, predict the volume of freight transported by railway, and analyze its trends using econometric and algebraic methods. Additionally, the study aims to determine the necessary measures to be taken in the future.
Poetic Perceptions of Childhood: Insights from Select Works of Walt Whitman and Muhammad Iqbal
Authors: Sohaib Sidra , Rafiq Prof. Sami
Published: March 2024

The paper incorporates Children’s Literature as a theoretical framework to study the innocent, imaginative, and inquisitive worlds of children. To achieve this goal, the researcher focuses on poems about childhood from two of the most celebrated writers of their respective nations, Walt Whitman (1819-1892) and Muhammad Iqbal (1877-1938). The paper is a study of textual and comparative analysis of the images of childhood as depicted in their works. Comparing the two writers of varied times and cultural backgrounds, the present study delves into an analysis of childhood as portrayed in their poetic works, Leaves of Grass (1855-1892) and The Call of the Marching Bell (1924), respectively. It strives to establish a relationship that despite their disparities, the innocence and curious nature of children remain the same. It also attempts to reveal the age-old values passed down through these timeless works. Literature connects readers surpassing linguistic and geographical barriers. By delving deep into Children's Literature as a field of study, readers share the collective experience of imagination and astonishment. It provides young readers with a vast vocabulary and unlocks the door to boundless imagination. Through this paper, it is emphasized that the innocence of children often leaves adult readers awestruck as they pose insightful questions that solve life's mysteries that elude us as grown-ups. The values, morals, and habits that children cherish and inherit long grown out of practice are to be talked about as how they impact the thinking of adults. The insights of this paper may contribute to the fields of Comparative Literature, Children’s Literature, and Cultural Studies in the global context.
Inventarisasi Kupu-Kupu (Lepidoptera: Rhopalocera) di Dua Kawasan Air Terjun Kota Padang, Sumatera Barat
Authors: Pratiwi Eka Ahda , Dahelmi Dahelmi
Published: March 2024

This study aims to identify of butterflies found in two waterfall areas in the city of Padang. Sampling was carried out in March - April 2018 with the transect walk method,  butterflies were captured using insect net. Total butterflies obtained were 179 individuals consisting of 51 species belonging to 37 genera and 7 families. The highest number of species found in the family Nymphalidae (17 species), followed by Papilionidae (10 species), Lycaenidae (6 species), Pieridae (6 species), Satyridae (6 species), Danaidae (4 species), and Amathusidae (2 species ) The most common species is Junonia atlites (Linnaeus).