bluuebunny/crossref_metadata_2025 huggingface dataset:
Predictors of Unfavorable Prognosis in Patients with Heart Failure After Cardioverter-Defibrillator Implantation According to the Prospective Part of the Kuzbass Registry
Authors: Lebedeva N. B. , Talibullin I. V. , Parfenov P. G. , Barbarash O. L.
Published: May 2024

Aim. Identification of clinical and instrumental predictors for non-arrhythmic death in patients with heart failure (HF) and implantable cardioverter-defibrillator (ICD).Material and methods. Through a telephone survey and examination of medical records from hospital and polyclinic databases, data were obtained on the alive/dead status and causes of death for 260 patients with heart failure (HF) and ICD included in the Kuzbass Registry of Patients with ICD. The follow-up period was 1.5 years. Clinical and instrumental parameters entered into the registry before the ICD implantation were included in a univariate and multivariate step-by-step analysis using the logistic (for qualitative variables) and linear (for quantitative variables) regression with calculation of regression coefficients and construction of a prognostic regression model. The quality of the created model was assessed using a ROC analysis.Results. During the observation period, 54 (20.8%) patients died. In 21 (38.8%) patients, death occurred in the hospital and was caused by acute decompensated heart failure in 15 (71.4%) patients, myocardial infarction in 3 (14.3%) patients, stroke in 1 (4.7%) patient, and pneumonia in 2 (9.5%) patients. 33 (61.2%) patients died outside the hospital; the cause of death was stated as the underlying disease associated with acute decompensated heart failure: in 9 (27.2%) patients, dilated cardiomyopathy; in 1 (3.0%) patient, rheumatic mitral disease; and in 23 (69.7%) patients, ischemic cardiomyopathy. According to the univariate regression model, the risk of death in the long-term period was increased by the QT interval prolongation (U 2.41, p = 0.0161); elevated pulmonary artery systolic pressure (U 4.30, p=0.0000) and increased left atrial size according to echocardiography (U 2.98, p=0.0029); stage IIB HF (OR 2.41; 95% CI: 1.26-4.6), NYHA III-IV (OR 3.03; 95% CI: 1.58-5.81); chronic obstructive pulmonary disease (OR 5.24; 95% CI: 2.04-13.45); and lack of optimal drug therapy (ODT) for HF before ICD implantation (OR 2.41; 95% CI: 1.29-4.49). The multivariate analysis identified the most significant factors included in the prognostic regression model: pulmonary artery systolic pressure above 45 mm Hg, social status, chronic obstructive pulmonary disease, and lack of ODT for HF.Conclusion. To ensure a maximum benefit from ICD, the factors that increase the likelihood of non-arrhythmic death should be considered before making a decision on ICD implantation. Particular attention should be paid to mandatory ODT for HF as the main modifiable risk factor for unfavorable prognosis.
Features of The Dynamics of Profibrotic Markers and Regression of Left Ventricular Hypertrophy After Renal Denervation in Patients With Resistant Hypertension and Stenosing Atherosclerosis of the Coronary Arteries
Authors: Zyubanova I. V. , Falkovckaya A. Yu. , Manukyan M. A. , Solonskaya E. I. , Vtorushina A. A. , Khunkhinova S. A. , Gusakova A. M. , Pekarskiy S. E. , Mordovin V. F.
Published: May 2024

Aim. To compare the changes in serum concentrations of matrix metalloproteinases (MMPs) and their tissue inhibitor (TIMP) to the dynamics of blood pressure (BP) and parameters of left ventricular hypertrophy (LVH) 6 months after renal denervation (RD) in patients with resistant arterial hypertension (RAH) and complicated coronary atherosclerosis.Material and methods. In 22 RAH patients with complicated coronary atherosclerosis (revascularization and/or history of myocardial infarction (MI)), 24-hour BP monitoring, echocardiography, and measurement of blood MMPs and TIMP were performed at baseline and six months after RD. The comparison group consisted of 48 RAH patients without a history of coronary revascularization or MI.Results. In 6 months after RD, BP was decreased comparably in both groups. In the group of complicated atherosclerosis, there were no significant changes in profibrotic markers or LVH parameters. Thus, at baseline and after 6 months, the values of the studied indicators were the following: left ventricular myocardial mass (LVMM) 233.1±48.1 and 243.0±52.0 g, LVMM index 60.6±14.5 and 62.8±10 .9 g/m2.7, proMMP-1 4.9 [2.1; 7.7] and 3.6 [2.0; 9.4]  ng/ml, MMP-2 290.4 [233.1; 352.5] and 352.2 [277.4; 402.9] ng/ml, MMP-9 220.6 [126.9; 476.7] and 263.5 [82.9; 726.2] ng/ml, TIMP-1 395.7 [124.7; 591.4] and 424.2 [118.2; 572.0] ng/ml, respectively. In the comparison group, on the contrary, there was a significant decrease in LVMM from 273.6±83.3 g to 254.1±70.4 g, LVMM index from 67.1±12.3 to 64.0±14.4 g/m2.7, proMMP-1 from 7.2 [3.6; 11.7] to 5.9 [3.5; 10.9] ng/ml, MMP-2 from 328.9 [257.1; 378.1] to 272.8 [230.2; 343.2] ng/ml, MMP-9 from 277.9 [137.0; 524.0] to 85.5 [34.2; 225.9] ng/ml, and the MMP-9/TIMP-1 ratio from 0.80 [0.31; 1.30] to 0.24 [0.07; 0.76]. The BP dynamics in this group was inversely correlated with MMP-2 at 6 months (r=-0.38), and the MMP-9/TIMP-1 ratio was correlated with LVMM and the LVMM index at baseline (r=0.39 and r=0.39) and at 6 months (r=0.37 and r=0.32). The change in TIMP-1 from 543.9 [277.5; 674.1] to 469.8 [289.7; 643.6] ng/ml was not significant (p=0.060).Conclusion. In RAH patients with complicated coronary atherosclerosis, the dynamics of profibrotic biomarkers and LVH parameters after RD was absent despite the pronounced antihypertensive effect, probably due to the low reversibility of cardiovascular remodeling processes or more complex regulatory mechanisms of the MMP system.
Clinical, Anamnestic, and Demographic Characteristics of Patients with Myocardial Infarction in Russian Federation According to the Russian Registry of Acute Myocardial Infarction – REGION–IM
Authors: Boytsov S. A. , Shakhnovich R. M. , Tereschenko S. N. , Erlikh A. D. , Pevsner D. V. , Rytova Yu. K. , Gulyan R. G. , Markov I. A. , Shchepinova L. V. , Fomina M. A. , Kletkina A. S. , Grigoreva T. V. , Dagaeva V. I. , Devyatova L. S. , Chesnokova L. Yu. , Semenova E. S. , Kamenetz Ya. A.
Published: May 2024

Aim. Based on data from the Russian REGION-MI registry, to characterize patients with myocardial infarction (MI) hospitalized in Russian hospitals, describe their historical, demographic, and clinical characteristics, and compare the results with the data of previous Russian and international registries of acute coronary syndrome.Material and methods. REGION-MI is a multicenter prospective observational study. The follow-up period was divided into three stages: during the hospital stay, at 6 and 12 months after the inclusion in the registry. Demographic and historic data and information about the present case of MI were entered into the patient’s individual record card.Results. The median age of all patients was 63 years; 68% of patients were men. The mean age of women was older than that of men. Among all MI cases, 70% were ST-segment elevation myocardial infarction (STEMI). Patients with non-ST-segment elevation myocardial infarction (NSTEMI) were older and had more comorbidities than patients with STEMI. The median time from the first symptoms to ECG recording was two hours, and from the first symptoms to CAG 7 hours. CAG was performed in 91% of patients with STEMI and 84% of patients with NSTEMI. Stenting was performed in 69% of patients. Although many patients had a complicated cardiovascular history, at the time of admission only 31.5% of patients were taking at least one drug from the groups of antiplatelets, oral anticoagulants, statins, and beta-blockers.Conclusion. Patients with MI in the Russian Federation are younger than patients with MI in European countries. Among the clinical and historical characteristics, conspicuous is the presence of modifiable risk factors in many patients, as well as the presence of a previous diagnosis of ischemic heart disease. Furthermore, a small proportion of patients took statins, antiplatelet agents or anticoagulants at the outpatient stage, which indicates a great reserve of both primary and secondary prevention of cardiovascular diseases in the Russian Federation. The delayed seeking medical help is also noticeable, which indicates the need for increasing the public awareness of the symptoms of MI and the importance of timely hospitalization.
R&D Tax Incentive Implementation Rate: A Novel Approach to Analysing Attractiveness of Tax Incentives
Authors: Marmilava Katsiaryna
Published: May 2024

The article discusses the current methodology used to evaluate relative attractiveness of R&D tax incentives, namely the B-index. It describes the evolution of the methodology, as well as its main limitations and drawbacks. It further suggests a novel complementary approach to analysing the attractiveness of tax incentives taking into consideration the practical implementation of tax incentives. The developed indicator – the tax incentive implementation (utilisation) rate – accounts for countries’ national features of tax incentive systems and reporting on R&D tax expenditures, and allows the generosity of tax incentives to be linked with the actual amount of tax support received by firms. The specific tax incentive implementation rates were computed for 20 European countries, and compared to draw conclusions about the relative efficacy of policy implementation.
Fast Changes in Food Retailing Due to the Impact of COVID-19
Authors: Sikos T. Tamás , Molnár Dóra
Published: May 2024

In this study, the impact of the pandemic COVID-19 on the FMCG sector is being examined. We consider as an important question to analyze in which direction the retail sector has shifted, whether it has been able to react to the sudden and increased online market challenge. How do offline and online food retailing relate to each other? What new challenges will be shopping face in the future, how is retailing adapting to them and how can artificial intelligence support these retail processes? What new innovations are expected in future retailing and how can domestic market players adapt to them?
Advancing New Views on the Causes and Prevention of Skin Cancer and Aging of the Skin
Authors: Chiou Win L.
Published: May 2024

The prevailing belief is that sunlight, particularly UV rays, leads to skin damage that accumulates, potentially causing skin cancer and photoaging. Consequently, avoiding or reducing sun exposure is widely advised. This stance, however, challenges the principle of genomic stability, which is essential for the healthy and appearance-preserving progression of generations, potentially except when damage stems from severe sunburn. This leads to the concept of non-cumulative, non-detrimental DNA damage. Such a groundbreaking perspective could profoundly impact research into the causes and prevention of skin cancer and skin aging. Key insights include: the key to prevent skin cancer is to prevent severe sunburn, not chronic moderate sun exposure that could guard against skin cancer; sunscreen is not recommended for intense intermittent sun exposure; long-term regular sun exposure may not lead to wrinkles and sagging; the intrinsic factor dominates skin aging; the UVA blockers in sunscreens might be unnecessary; traditional methods of using bolus UV doses could be problematic; low SPF sunscreens (2-8) might suffice; ultraviolet-protective clothing is advisable; some issues related to tanning salons and tinted glasses are raised; the critical role of water and nutrients is emphasized; effects of wind and heat are considered; and tissue-regenerating moisturizers are recommended for skin protection.
Impacto da tecnologia na educação
Authors: Foina Paulo Rogério
Published: May 2024

A tecnologia vem impactando toda a sociedade, não só pelos benefícios em conforto e aumento deprodutividade, mas também, principalmente, alterando as relações humanas e a forma como o poder éexercido. Estamos no momento de transição onde convivempráticas, conceitos e valores dos séculospassados com comportamentos, valores e estruturas do século XXI. Essa coexistência, nem semprepacífi ca, é o maior desafi o que os atores políticos da sociedade (incluindo professores e operadores daeducação) enfrentam no seu dia a dia.
Beneficios de la formación empresarial para mujeres con renta baja
Authors: Xavier Corrêa de Morais Léa Paula Vanessa , Dandolini Gertrudes Aparecida , Vaz Caroline Rodrigues
Published: May 2024

El objetivo de esta revisión sistemática es identificar los beneficios percibidos por las mujeres de bajos ingresos cuando participan en intervenciones de educación empresarial. El corpus final incluyó 11 artículos empíricos a partir de los cuales se identificaron 69 beneficios señalados por las mujeres, categorizados en siete grupos según su similitud: financieros; status social; salud mental y calidad de vida; desarrollo de habilidades; desarrollo personal; cuestiones de género; y poder de decisión. La conclusión es que no existe una estandarización en la recogida de datos en los estudios analizados y que la percepción de los beneficios varía de una mujer a otra en función de su contexto actual y de la complejidad de la intervención realizada. Se observa que los autores aún no se relacionan entre sí y, por lo tanto, es necesario profundizar en el tema para identificar los factores que representan el contexto en busca de mejores intervenciones y sus resultados prácticos.
Social Technologies for Social Inclusion in Traditional Communities in the Amazon
Authors: Chaves Maria do Perpétuo Socorro Rodrigues , Almeida Antônia Lúcia Silva de , Chaves João Marcelo Rodrigues
Published: May 2024

There is a widely recognized consensus in contemporary society and the academic community that education is crucial for a nation's socioeconomic development. This paper presents the research experience, outreach, and curricular internship of the Grupo de Pesquisa Interação, employing the Interaction Method (Action-Research) approach to train professionals for working with riverside communities in the Amazon region. The research employs a comprehensive set of data collection techniques, such as bibliographic and documentary research, semi-structured surveys, interviews with key informants, and both group and individual dynamics with domestic-family groups to encourage participation from local community members and institutions. The results aim to provide community organizations and domestic-family groups with environmentally sustainable innovations and social technologies. Additionally, they offer qualified support to regional public policy institutions for developing affirmative actions geared towards citizenship and social inclusion.
The importance of primary education in Brazil, in the context of the fourth industrial revolution
Authors: Fernandes Gilberto
Published: May 2024

Based on the analysis of the main factors driving the Fourth Industrial Revolution and its current stageof evolution, and considering the possible social and economic impacts, particularly regarding theelimination of traditional jobs and the creation of new occupations, this article examines the importanceof Basic Education, with a focus on the necessary adaptation of teaching methodologies, as ways offacing the challenges and taking advantage of new the opportunities that arise.
Gerenciando riscos, discrição e lucros extraordinários: uma análise dos agentes dos operadores e gestores de hedge funds
Authors: Bichoffe Ana Carolina
Published: May 2024

Esse artigo oferece um balanço preliminar de uma pesquisa sobre analistas, traders e gestores financeiros brasileiros que operam hedge no mercado de derivativos. Incipiente, inclusive no debate da sociologia das finanças internacional, os hedge funds são a representação e consolidação de estrutura de investimentos considerada vanguarda entre investimento e risco. Assim, com base em um conjunto de entrevistas semiestruturadas, o trabalho busca descrever e analisar os processos de acumulação dos recursos materiais e simbólicos necessários para garantir ou facilitar a entrada, permanência e circulação dos agentes no espaço de hedge funds.
Mulheres negras na música: estudos de caso de cinco musicistas no Maranhão
Authors: Keller Paulo F. , Elias Lorena de O.
Published: May 2024

O presente artigo tem por objetivo apresentar reflexões e análises do trabalho artístico musical de cinco musicistas maranhenses: Patativa, Célia Sampaio, Lena Machado, Dicy Rocha e Núbia Rodrigues – mulheres negras presentes no cenário da música maranhense. Problematizamos a questão do trabalho artístico musical e como as cinco musicistas, que compõem os estudos de caso, estão inseridas na produção artística musical e no mercado da música em São Luís-MA. Por metodologia utilizamos abordagens da Sociologia do Trabalho Artístico e da Sociologia da Arte e da Música, em uma pesquisa qualitativa com base em estudos bibliográficos e documentais, na observação direta das cenas musicais e na realização de entrevistas semidirigidas com as musicistas. Constatamos fatores que condicionam o trabalho artístico das mulheres negras na cena musical maranhense, tais como o trabalho intermitente, as múltiplas jornadas de trabalho, a falta de infraestrutura local adequada, a instabilidade financeira e de carreira, e uma busca pelo seu reconhecimento profissional e de apoio dos setores público e privado.
Audiovisual brasileiro sofreu censura? Abordagem exploratória da cobertura midiática entre 2019 e 2020
Authors: Bispo Bruno Vilas Boas , Mota Gabriela Protásio , Lobo Rafaela Santiago
Published: May 2024

Considerando a assunção de um governo neoconservador, que defende o controle direto da produção cultural e artística, apresentaremos uma visão geral de notícias envolvendo ações governamentais que afetaram a produção audiovisual no país, tendo como escopo alguns indícios de práticas de censura. Utilizamos “Alertas do Google” com palavras-chave associadas ao assunto, resultando em um banco de dados com as notícias. Classificamo-las em: arquitetura institucional; nomeações e demissões de cargos essenciais; ações e omissões; pressões e controvérsias; e reclamações de censura envolvendo o governo e outras instâncias do Estado ou da sociedade civil. Além disso, realizamos uma breve discussão teórica sobre censura em diálogo com produções de Maria Cristina Castilho Costa. Provisoriamente, observamos sinais de um boicote à indústria audiovisual pari passu a medidas que sugerem práticas de censura difusa, exigindo mais pesquisas e uma reelaboração do conceito clássico de censura.
Na trilha de Paul Ricoeur: caminhos possíveis na pesquisa em educação em ciências e matemática
Authors: Aranha Carolina Pereira
Published: May 2024

Com base na interrogação: “De que formas as ideias de Paul Ricoeur podem compor processos de análise em pesquisas na área de Educação em Ciências e Matemática?”, intenciona-se, por meio deste texto, contribuir com pesquisadoras e pesquisadores, em especial, da área de Educação em Ciências e Matemática que desejam explorar a linguagem em seus estudos, instigando reflexões e novos questionamentos, ao mesmo tempo em que apresenta-se possíveis caminhos a serem trilhados nessa área de pesquisa, no que se refere à hermenêutica de Paul Ricouer. Para tanto, o texto trata, brevemente, sobre o filósofo francês em foco, Paul Ricoeur, e suas principais obras bem como um dos modos de adentrar em seu mundo. Em seguida, discorre-se sobre sua hermenêutica e alguns dos principais conceitos relacionados a ela e, por fim, destaca-se alguns dos estudos presentes em teses e dissertações que tomaram as ideias de Paul Ricouer como orientações para análises de dados produzidos.
On the trail of Paul Ricouer – possible paths in research in science and mathematics education
ABSTRACT
Based on the question, "In what ways can Paul Ricoeur's ideas compose analysis processes in research in the field of Science and Mathematics Education?", this text aims to contribute to researchers, especially in the area of Science and Mathematics Education who wish to explore language in their studies, instigating reflections and new questions, while presenting possible paths to be followed in this area of research with regard to Paul Ricoeur's hermeneutics. To this end, the text briefly addresses the French philosopher in focus, Paul Ricoeur, and his main works as well as one of the ways to enter his world. Then, it discusses his hermeneutics and some of the main concepts related to it, and finally, highlights some of the studies present in theses and dissertations that have taken Paul Ricoeur's ideas as guidelines for the analysis of produced data.
Keywords: Hermeneutics. Triple Mimesis. Data analysis.
Aicardi syndrome – case report and literature review
Authors: Ochman-Pasierbek Patrycja , Olczyk Przemysław , Paprocka Justyna , Machnikowska-Sokołowska Magdalena , Doman Adrianna
Published: May 2024

Zespół Aicardiego (Aicardi syndrome – AS) to rzadkie zaburzenie neurorozwojowe, w zdecydowanej większości przypadków występujące u dziewcząt. Zazwyczaj charakteryzuje się klasyczną triadą objawów: napadami zgięciowymi, agenezją ciała modzelowatego i chorioretinalnymi ubytkami w siatkówce. Należy również podkreślić, że padaczka lekooporna jest często głównym objawem klinicznym AS. Ponadto u pacjentów stwierdza się niepełnosprawność intelektualną, zmiany w obrębie narządu wzroku, twarzoczaszki, a także inne zaburzenia neurorozwojowe. W pracy przedstawiono przypadek pacjentki z AS z lekooporną padaczką. Pacjentka jest leczona od 3 miesiąca życia, jednak kolejne modyfikacje farmakoterapii nie doprowadziły do ustąpienia napadów. Istnieje potrzeba prowadzenia dalszych badań, aby właściwie odnieść się do kwestii skutecznego leczenia AS.
Evolución espacio-temporal de las unidades de ordenamiento ambiental (ZPB, ZPAES) y el refugio de vida silvestre de Los Pantanos de Villa, Perú (1987-2022)
Authors: Fabian Tolentino Elveis Daniel , Torres Cordero Nina Aleli , Bardales Martínez María Fernanda , Naquiche Yesquen Dagnert Luis , Ramírez Huaroto Dámaso Wilfredo
Published: May 2024

Los humedales costeros adyacentes a zonas urbanas, como los Pantanos de Villa en la ciudad de Lima, Perú, están sujetos a cambios constantes en el uso del suelo debido a la interacción antropogénica. Esto ha llevado a la reducción de áreas de vegetación densa, dando paso a zonas edificadas. Por esta razón, el presente artículo aborda la problemática de los cambios físicos experimentados en las zonas urbanas adyacentes al humedal, como las unidades de ordenamiento ambiental, en este caso la Zona de Protección de Afloramiento y Escorrentía Superficial (ZPAES y la Zona de Protección Paisajística de Borde (ZPB), así como el Refugio de Vida Silvestre Pantanos de Villa (RVSPV), como consecuencia de la rápida expansión urbana. Por ello, el objetivo de esta investigación es analizar la evolución espacial y temporal del entorno de los Pantanos de Villa y la urbanización dentro de las Unidades de Ordenamiento Ambiental ZPB, ZPAES y el RVSPV. Para ello, se utilizó la plataforma de Google Earth Engine (GEE) y se procesaron imágenes satelitales de los sensores Landsat 5 TM y Sentinel 2 MSI. Estas imágenes se trabajaron en la interfaz de GEE y se analizaron utilizando índices espectrales, NDVI y NDBI, mediante códigos de álgebra de mapas y el enmascaramiento de píxeles. Para la representación cartográfica, se empleó un Sistema de Información Geográfica (SIG). Los resultados muestran un aumento del 291.12% en la superficie edificada y una reducción del 26% en la superficie vegetal en los últimos 35 años, para las Unidades de Ordenamiento Ambiental ZPB y ZPAES, y el RVSPV. La reducción identificada se relaciona directamente con la expansión no planificada de la superficie urbana y las actividades antropogénicas.
Positive Phototaxis of Pulse Weevil, Callosobruchus chinensis under the Influence of Artificial Light
Authors: Mukherjee Abhishek , Maji Soumya , Pal Anish
Published: May 2024

Background: Managing insect pests with less environmental hazards is one of the biggest challenges of this century; therefore, new, eco-friendly alternative ways such as electric traps, bait traps or bio-pesticides are gaining great attention. Most economic and effective method is managing agriculture pest by using light trap. Methods: In this study, the phototactic response of Callosobruchus chinensis towards different wavelengths (red 620 nm; green 520 nm; blue 470 nm) of light (LED) at different intensities (25, 50, 100 lux) and durations (2, 6, 12, 24 h) was investigated in a Y maze chamber. Phototactic responses were also observed for IR (730 nm) and UV (365 nm) at different durations (2, 6, 12, 24 h). Result: The rate of insect attraction was different for different wavelengths of light. The duration of the intended light also showed a positive response to the attraction rate of the insect, as in every case, 24 hours of duration showed the maximum attraction. The green light showed the highest attraction rate (77.78%) at an intensity of 50 lux for 24 h duration, followed by blue (74.44%) and red (65.56%) light at an intensity of 25 lux for 24 h duration (each). UV (65.56%) also showed a positive attraction at 24 h duration, but IR (52.22%) showed the least attraction. These results suggest that green and blue wavelengths can be most useful for monitoring and mass trapping of C. chinensis.
Water Imprints: Experiments Unfolding History and Landscape
Authors: Perez Lopez Irene
Published: May 2024

The article is presenting the research designed to unfold original landscapes and discover the transformation of Mulubinba into Newcastle (New South Wales, Australia), through the construction of a visual narrative across time. The time frame spans hundreds of years of history, focusing on the impacts of urban, industrial, riverfront and coastal metamorphosis, uncovering new and unexpected relationships between space, community, and environments. The method combines quantitative data analysis and qualitative research, compiling and representing spatial transformation through time, utilising an exhaustive process of mapping.
Illustration Research: Exploring the role of Non-traditional Research Outcomes and Exhibition
Authors: Chand Ari , Howells Andrew , Male Alan , Minichiello Mario , Killen Chloe , O’Donnell Luke , Barnes-Keoghan Alex
Published: May 2024

Illustration is a robust and internationally established academic discipline. It engages a multiplicity of disciplinary subject matter and is investigated in-depth by a range of fields and approaches including, but not limited to, practice-based research, design studies, and cultural production. Illustration is fundamental to our understanding of the world as it operates across a diverse range of our engagement with everyday life and experience. After all, we learn to read images before we learn to speak and read any other form of language. This paper outlines the burgeoning role of illustration outcomes as Non-Traditional Research Outcomes (NTROs) within the Academy. With NTROs increasingly being recognized within universities, clarity around how illustration as a field of research meets requirements and is comparable to traditional research approaches is needed. Additionally, this paper seeks to showcase an exhibition of international illustration researchers titled Seeking Vision: A Virtual Exhibition of Illustration Research. This exhibition of 25 international illustration academics included creative outputs accompanied by written research statements for broader context. The result was a diverse range of outputs and approaches which signifies the complexity of the growing international research community on illustration.
Infancia y ruralidad
Authors: Ávila Garzón Liliana Inés
Published: May 2024

En la historia de la humanidad las comunidades han tenido distintas experiencias en la crianza de los niños y las niñas. En el caso de las ruralidades, la crianza se ha llevado a cabo de maneras diversas, basándose en su cosmovisión de la vida familiar y comunitaria, de los imaginarios que las sociedades rurales tengan en su momento histórico y político, así como de las oportunidades que el medio económico y biofísico les proporcione. La comprensión y el reconocimiento de estas experiencias se consideran una deuda académica, social y política con las infancias rurales, lo cual motivó los objetivos de esta investigación. Por ello, a través de un estudio múltiple de caso, se identifica y da cuenta de la configuración de la primera infancia en la vereda Huerta Grande del municipio de Boyacá, Colombia, a partir de cuatro ejes fundamentales: la caracterización de los medios de vida de seis familias que habitan en la vereda, la identificación de las experiencias de crianza a través de las dinámicas del entorno familiar, el análisis de los procesos de acompañamiento a las experiencias de crianza desde las acciones institucionales en primera infancia, y la indagación de la experiencia de la primera infancia según los propios niños y niñas.
Solución tecnológica para la atención de emergencias en establecimientos de salud de tipo 1 y 2 del sector rural
Authors:   , Paco Huerta Renato Francisco , Iriarte Palacios Oscar Gonzalo
Published: May 2024

El propósito de este proyecto es llevar a cabo la ejecución de una solución tecnológica que mejore la calidad de la atención de emergencias en establecimientos de salud en zonas rurales. Para lograr este objetivo se llevará a cabo el desarrollo de la implementación de una solución tecnológica que permita incorporar una gestión de procedimientos y herramientas en base a recomendaciones de uno o varios médicos especialistas. La ejecución del proyecto para la atención de emergencias en establecimientos de salud de tipo 1 y 2 del sector rural usando telemedicina y comunicación sincrónica nos permitirá optimizar la calidad y tiempos de atención, cumpliendo con los objetivos establecidos para la mejora de indicadores de eficiencia en los servicios prestados, permitiendo ayudar a muchas vidas en zonas alejadas de las grandes ciudades. La investigación y análisis de métodos de implementación de telemedicina compatibles con las necesidades presentes en nuestra realidad nacional serán fundamentales para el desarrollo correcto de las funciones que se utilizarán en el presente proyecto. La implementación de la telemedicina contribuirá al futuro desarrollo de otras aplicaciones, las cuales podrán complementar este modelo de prestación de servicios llevándolo a un ciclo de mejora continua y calidad. Por ello, se ha definido que el producto final, será una solución tecnológica que nos permitirá validar la implementación de la telemedicina en zonas rurales del Perú y de esta manera se podrá contribuir al desarrollo del sistema de salud nacional con una propuesta de proyecto tecnológico que innove en la prestación de servicios médicos de emergencia nacionales.
Relación entre digitalización y desempeño logístico verde de los agentes de carga en el Perú durante el periodo 2017 - 2022
Authors:   , Vente Colán Thalia , Hidalgo Lucano Maria
Published: May 2024

En los últimos años, el comercio exterior se ha convertido en una de las actividades económicas más significativas para el Perú. Sin embargo, la apertura al mercado internacional se ha visto impactada por nuevas exigencias que promueven un comercio más sostenible. A nivel nacional, las agencias de carga, actores principales del comercio exterior, muestran un deficiente desempeño logístico verde. Por ello, nace la necesidad de realizar este estudio, cuyo objetivo principal es determinar la relación entre la digitalización y el desempeño logístico verde de los agentes de carga con presencia en Perú durante el periodo 2017 – 2022, ya que la implementación de herramientas digitales permitirá que el Perú sea más competitivo y medioambientalmente responsable frente a las nuevas normativas del comercio. Para el desarrollo, se aplicó una metodología con enfoque de tipo cuantitativo, alcance descriptivo-correlacional y un diseño no experimental y transversal. Para la recolección de datos se encuestó 47 agencias de carga habilitadas con presencia en Perú que evidencian prácticas sostenibles en su web. Como resultado, se obtuvo un coeficiente de correlación 0.295 del planteamiento de la hipótesis principal y se concluyó que la digitalización sí se relaciona con el desempeño logístico verde en el periodo 2017-2022.
Conductas de autocuidado y desregulación emocional en hospitales de Lima Metropolitana
Authors:   , Carquin Villanueva Claudia , Salazar Loza Valeria
Published: May 2024

Introducción: La expansión de la COVID-19 ha evidenciado la ardua labor de los enfermeros; sin embargo, estos muestran inadecuada protección, sentimientos de frustración, fatiga física y especialmente emocional, generando problemas de salud mental. Objetivo: Analizar la relación entre conductas de autocuidado y desregulación emocional en enfermeros de Lima Metropolitana. Método: Muestra de 205 enfermeros (12,7% varones y 87,3% mujeres) entre 21 y 60 años de edad, evaluados con la Escala de Autocuidado Profesional y la Escala de Dificultades de Regulación Emocional. Resultados: Se evidenció que el autocuidado profesional se vinculó positivamente con la desatención emocional, siendo de magnitud baja y oscilando entre .14 y .28. Asimismo, el autocuidado físico se vinculó positivamente con interferencia emocional y en una magnitud baja de .24; mientras que, descontrol, confusión y rechazo emocional no demostraron asociación significativa. Conclusión: La implementación de prácticas de autocuidado en las jornadas laborales de los enfermeros, incrementó las dificultades de regulación emocional; puesto que siempre se encuentran expuestos al estrés, preocupación y responsabilidad dentro del área COVID-19. Finalmente, se plantean las implicancias del estudio, conclusiones y recomendaciones.
Pollen indices of Cedrus atlantica Manetti populations vary with geographical localities in the Moroccan Atlas Mountains
Authors: SENGHOR Codou Senghor , SAOUAB Fatima-Ezzahra , BENDRISS AMRAOUI Mohammed
Published: May 2024

North Africa’s forests of Cedrus atlantica Manetti have declined drastically, by more than 58% in the last 130 years, and many stands are likely to disappear entirely in the coming decades. This study on the interactions between C. atlantica pollen characters (production, germination, and pollen tube length) and locality characters in Morocco, using seventy individuals from seven geographically distant populations, showed that pollen indices varied according to station. Pollen production was high in the populations of the Moudemam-1 and Seheb stations, intermediate in the Ait Oufella and Ait Ayach stations, and low in the Zerrouka, Ras Elma and Moudemam-2 stations. Pollen germination was very low for the populations in the Seheb and Moudemam-1 stations but high in the other stations. On the other hand, the longest pollen tubes were recorded in the Moudemam-1 population, while those in the other stations were shorter. These results show an inverse variation between the pollen indices characterizing the populations of the stations studied. The shortest pollen tube length classes [0-100] to [300-400] accounted for 85.98% of all classes and were assessed for the Zerrouka, Ait Oufella and Ait Ayach stations. The other classes were more represented or exclusive to the population of the Moudemam-1 station. These results could have implications not only for assessing pollen variations according to geographical localities but also for optimizing fertilization in cedar forests by selecting the best clones for this species.
Nowe święto 3 maja. Ustanowienie obchodów rocznicy zniesienia pańszczyzny przez Rusinów galicyjskich
Authors: Dwornik Kamil
Published: May 2024

15 maja 1848 roku w trakcie Wiosny Ludów zniesiono obowiązek wykonywania pańszczyzny przez chłopów w Galicji. „Podarunek cesarski” wywołał głębokie zmiany społeczne i gospodarcze na wsi. Z uwagi na strukturę społeczną Rusinów galicyjskich, której podstawę stanowiło chłopstwo, wydarzenie to zaczęło nabierać charakteru wyzwolenia narodowego spod władzy polskich feudałów. Jego pierwsza rocznica została wykorzystana przez ruskie duchowieństwo greckokatolickie do zainicjowania publicznych praktyk upamiętnienia. Zgodnie z używanym przez Cerkiew kalendarzem juliańskim rocznica wypadała w dniu 3 maja, stąd nowa uroczystość zyskała miano „święta 3 maja”. W 1849 roku zorganizowano pierwsze obchody, w trakcie których Naczelna Rada Ruska wyraziła wdzięczność domowi panującemu, a jednocześnie przeprowadziła akcję, mającą na celu narodowe uświadomienie i integrację zgromadzonych mas.
Dwie nowoczesności Nowej Huty
Authors: Łatała Katarzyna , Wielecki Kamil M.
Published: May 2024

Teza, której bronimy w artykule, jest dwojaka. Po pierwsze, twierdzimy, że Nowa Huta przeszła przez dwie nowoczesności — socjalistyczną i postsocjalistyczną. Krakowska dzielnica jest punktem węzłowym, w którym te dwie nowoczesności — a być może i więcej — splatają i ścierają się ze sobą. Po drugie, argumentujemy, że Nowa Huta stanowi materialny znak ciągłości i zerwań polskiej historii. Stoi ona w centrum polskich sporów tożsamościowych, w których strony zawsze muszą się jakoś ustosunkować do socjalistycznej przeszłości.
Dla jednych — symbol zbrodniczego systemu narzuconego przez radzieckiego okupanta, inżynierii, której poddano polskie społeczeństwo i synonim szpetoty. Choć również miejsce walki o krzyż i oporu, który klasa robotnicza stawiła rzekomo reprezentującej ją partii. Dla drugich — element dziedzictwa kulturowego, które trzeba chronić; realizacja progresywnych ideałów sprawiedliwości społecznej, a współcześnie najbardziej zielona dzielnica Krakowa.
Teoretycznymi podstawami naszej argumentacji są teoria wielu nowoczesności Shmuela Eisenstadta oraz teoria dwóch nowoczesności Susanne Brandtstädter. Rozpoczynamy od omówienia nowoczesności okresu socjalistycznego w Nowej Hucie opierając się na treściach ówczesnej sztuki propagandowej oraz krytycznej, tworzących narrację o dzielnicy. Następnie przechodzimy do okresu postsocjalistycznego, analizując zmiany, którym w wyniku transformacji ustrojowej podlegała Nowa Huta i dyskurs o niej. Na zakończenie porównujemy nowoczesność postsocjalistyczną do socjalistycznej.
MEDIATING THE GREEK-TURKISH CONFLICT: THE EFFICACY, CHALLENGES, AND INNOVATIVE PATHWAYS OF NATO'S INTERNAL MECHANISMS
Authors: Jie Sun
Published: May 2024

The ongoing conflict between Greece and Turkey poses significant challenges to regional stability, highlighting the critical role of NATO in mediating such disputes. This paper examines the efficacy of NATO's internal mechanisms in mediating the Greek-Turkish conflict, identifies the key challenges these mechanisms face, and explores innovative pathways for resolution. Employing a mixed-methods approach that includes a literature review, case studies, and comparative analysis, we uncover the strengths and limitations of NATO's current conflict resolution strategies. Our findings reveal that while NATO's mechanisms have facilitated dialogue, political divergences among member states and external geopolitical pressures have often hindered effective mediation. The paper proposes innovative solutions, including enhancing preemptive conflict management tools, establishing more inclusive dialogue platforms, and incorporating technology in mediation processes. These suggestions aim to bolster NATO's role in the Greek-Turkish context and future international conflicts, contributing to a more stable and peaceful international order.
CONFIGURABLE NAIVE BAYES IMPLEMENTATION ON FPGA USING PARTIAL RECONFIGURATION
Authors: El Bouazzaoui Achraf El Bouazzaoui
Published: May 2024

The Naive Bayes classifier is a fundamental algorithm in machine learning, known for its simplicity and effectiveness in various predictive modeling scenarios. However, its deployment in real-time applications demands efficient hardware implementations that can adapt dynamically to varying computational needs and model specifications. This work presents a novel FPGA-based implementation of Naive Bayes classifiers that leverages partial reconfiguration to enhance flexibility and resource efficiency. Our method employs a modular architecture that allows seamless switching among various Naive Bayes models, such as Gaussian, Multinomial, and Bernoulli, enhancing system flexibility without halting ongoing processes. By utilizing partial reconfiguration, our implementation minimizes the FPGA resource utilization, enabling more efficient use of hardware. We thoroughly evaluate our system, focusing on reconfiguration time and resource efficiency. We demonstrate that our approach provides the operational flexibility needed for real-time data processing tasks, enabling quick adaptation to variable data types and distributions without interrupting ongoing processes. This adaptive framework supports dynamic scenarios, facilitating immediate updates in response to evolving conditions with minimal downtime.
Manual Handling as Contributor of Low Back Pain for Workers: A Case Study at PT Sumber Mandiri Jaya, Kabupaten Merauke
Authors: Sambeko Boyke Elyas Michael , Susanto Nugroho , Alfanan Azir
Published: May 2024

Introduction: Manual handling activities are a main causative factor of low back pain injuries. Around 1.71 billion people worldwide live with musculoskeletal conditions, including low back pain. In the Southeast Asia region, it is estimated that around 369 million people experience low back pain. In Indonesia more than 11.9% of health workers are diagnosed with musculoskeletal disease and diagnostic specific for worker obtained 24.7%. The purpose of this study was to determine the dominant indicators of manual handling for low back pain. Method: Study design used is cross-sectional study. Sample was 62 subjects. The variables of low back pain were collected using a modified questionnaire adopted from the Oswestry Low Back Pain Disability Questionnaire. Data were analyzed with linear regression test for the main indicators contributing to low back pain. Result: Average age of workers is 26.06±7.28, education level senior high school 45%, under 4 years length of work 83.9%. Average manual handling variable is 613.45 ± 383.39, low back pain 6.48 ± 3.607. Manual handling is not significantly related to low back pain r = -0.182. Duration, frequency and load are significant in predicting low back pain. The factors of duration, frequency and lift were estimated to contribute 5.4% for low back pain. Conclusion: The main factors related to low back pain are lifting load for workers, while the factors of lifting duration and frequency are not significantly related to low back pain. The lifting load is the main factor contributing to low back pain.
Eighth Annual Report on Antimicrobial Agents Intended for Use in Animals
Authors:   WOAH
Published: May 2024

Since 2015, the World Organisation for Animal Health (WOAH) has been monitoring the use of antimicrobials in animals – one of today’s most urgent global health threat. Every year, the Organisation publishes a report on the global and regional trends. The 8th annual report, published in 2024, highlights the trend on the use of antimicrobials in the animal health sector.
Advancing CAR T-cell therapy for chronic lymphocytic leukemia: exploring resistance mechanisms and the innovative strategies to overcome them
Authors: Borogovac Azra , Siddiqi Tanya
Published: May 2024

Chimeric antigen receptor (CAR) T-cell therapy has ushered in substantial advancements in the management of various B-cell malignancies. However, its integration into chronic lymphocytic leukemia (CLL) treatment has been challenging, attributed largely to the development of very effective chemo-free alternatives. Additionally, CAR T-cell responses in CLL have not been as high as in other B-cell lymphomas or leukemias. However, a critical void exists in therapeutic options for patients with high-risk diseases who are resistant to the current CLL therapies, underscoring the urgency for adoptive immunotherapies in these patients. The diminished CAR T-cell efficacy within CLL can be traced to factors such as compromised T-cell fitness due to persistent antigenic stimulation inherent to CLL. Resistance mechanisms encompass tumor-related factors like antigen escape, CAR T-cell-intrinsic factors like T-cell exhaustion, and a suppressive tumor microenvironment (TME). New strategies to combat CAR T-cell resistance include the concurrent administration of therapies that augment CAR T-cell endurance and function, as well as the engineering of novel CAR T-cells targeting different antigens. Moreover, the concept of “armored” CAR T-cells, armed with transgenic modulators to modify both CAR T-cell function and the tumor milieu, is gaining traction. Beyond this, the development of readily available, allogeneic CAR T-cells and natural killer (NK) cells presents a promising countermeasure to innate T-cell defects in CLL patients. In this review, we explore the role of CAR T-cell therapy in CLL, the intricate tapestry of resistance mechanisms, and the pioneering methods studied to overcome resistance.
Graphene oxide membranes using MOF@Chitosan core-shell nanoparticles as dual modulators for dye separation
Authors: Wang Xingying , Guo Yongmei , Cui Xiaolei , Wang Zhikun , Zhang Zhihan , Tosheva Lubomira , Guo Hailing
Published: May 2024

Graphene oxide (GO) membranes hold significant promise for the water purification. However, they also face the problem of structural swelling, which limits their use in water treatment applications. In this work, a novel dual-modulated core-shell metal-organic framework@Chitosan (MOF@CS) was successfully synthesized and used as an intercalation cross-linker to optimize the interlayer spacing and stability of GO membranes. Molecular dynamics simulation confirms that MOF@CS, acting as an intercalator, accelerates the water diffusion rate within the channels of the GO layer compared to a pure GO layer. At the same time, Fourier Transform Infrared Spectroscopy analysis reveals that MOF@CS serves as a cross-linker for covalently cross-linking the GO layer. The nanofiltration performance and stability of the improved MOF@CS-GO composite membranes were significantly enhanced. Compared to the pure GO membranes, the MOF@CS-GO composite membranes exhibited enhanced Congo red rejection rates (from 76.5% to 95.6%) while maintaining a high pure water flux (34.5 L·m-2·h-1·bar-1) and good structural stability (stable dye removal performance over 120 h). This dual regulation strategy is expected to effectively solve the swelling problem of GO membranes in aqueous media and open up avenues for advancing their performance.