bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterization of Nutritional Quality Traits of a Common Bean Germplasm Collection
Authors: Murube Ester , Beleggia Romina , Pacetti Deborah , Nartea Ancuta , Frascarelli Giulia , Lanzavecchia Giovanna , Bellucci Elisa , Nanni Laura , Gioia Tania , Marciello Ugo , Esposito Stefania , Foresi Giacomo , Logozzo Giuseppina , Frega Giuseppe Natale , Bitocchi Elena , Papa Roberto
Published: July 2021

Food legumes are at the crossroads of many societal challenges that involve agriculture, such as climate change and food sustainability and security. In this context, pulses have a crucial role in the development of plant-based diets, as they represent a very good source of nutritional components and improve soil fertility, such as by nitrogen fixation through symbiosis with rhizobia. The main contribution to promotion of food legumes in agroecosystems will come from plant breeding, which is guaranteed by the availability of well-characterized genetic resources. Here, we analyze seeds of 25 American and European common bean purified accessions (i.e., lines of single seed descent) for different morphological and compositional quality traits. Significant differences among the accessions and superior genotypes for important nutritional traits are identified, with some lines showing extreme values for more than one trait. Heritability estimates indicate the importance of considering the effects of environmental growth conditions on seed compositional traits. They suggest the need for more phenotypic characterization in different environments over different years to better characterize combined effects of environment and genotype on nutritional trait variations. Finally, adaptation following the introduction and spread of common bean in Europe seems to have affected its nutritional profile. This finding further suggests the relevance of evolutionary studies to guide breeders in the choice of plant genetic resources.
Numerical Solution of Nonlinear Fractional Diffusion Equation in Framework of the Yang–Abdel–Cattani Derivative Operator
Authors: Malyk Igor V. , Gorbatenko Mykola , Chaudhary Arun , Sharma Shivani , Dubey Ravi Shanker
Published: July 2021

In this manuscript, the time-fractional diffusion equation in the framework of the Yang–Abdel–Cattani derivative operator is taken into account. A detailed proof for the existence, as well as the uniqueness of the solution of the time-fractional diffusion equation, in the sense of YAC derivative operator, is explained, and, using the method of α-HATM, we find the analytical solution of the time-fractional diffusion equation. Three cases are considered to exhibit the convergence and fidelity of the aforementioned α-HATM. The analytical solutions obtained for the diffusion equation using the Yang–Abdel–Cattani derivative operator are compared with the analytical solutions obtained using the Riemann–Liouville (RL) derivative operator for the fractional order γ=0.99 (nearby 1) and with the exact solution at different values of t to verify the efficiency of the YAC derivative operator.
Development and Evaluation of Simulation-Based Low Carbon Mobility Assessment Models
Authors: Moffatt Damian , Dia Hussein
Published: July 2021

The transport sector is a significant contributor to global emissions. In Australia, it is the third largest source of greenhouse gases and is responsible for around 17% of emissions with passenger cars accounting for around half of all transport emissions. Governments at all levels have identified a need for a reduction in transport carbon emissions to meet their net zero emissions targets. This research aims to help decision makers estimate the carbon footprint of transport networks within their jurisdictions and evaluate the impacts of emission-reduction interventions, through development of a simulation-based low carbon mobility assessment model. The model was developed based on a framework that integrates multiple mobility components including individual travel preferences, traffic simulation, and an assessment interface to create a seamless tool for the end-user. The feasibility of the assessment model was demonstrated in a case study for a local city council in Melbourne. In one of many scenarios reported in this paper, the model showed that maintaining current levels of emissions would require a 20% reduction in vehicle trips by 2030, and a much larger reduction would be required to reduce the levels of greenhouse gas emissions and achieve desired emissions reduction targets. The paper concludes with recommendations and future directions to extend the model’s capabilities and applications.
Horizon-K Farsightedness in Criminal Networks
Authors: Herings P. Jean-Jacques , Mauleon Ana , Vannetelbosch Vincent
Published: July 2021

We study the criminal networks that will emerge in the long run when criminals are neither myopic nor completely farsighted but have some limited degree of farsightedness. We adopt the horizon-K farsighted set to answer this question. We find that in criminal networks with n criminals, the set consisting of the complete network is a horizon-K farsighted set whenever the degree of farsightedness of the criminals is larger than or equal to (n−1). Moreover, the complete network is the unique horizon-(n−1) farsighted set. Hence, the predictions obtained in case of completely farsighted criminals still hold when criminals are much less farsighted.
Bioinformatics Analysis of Allele Frequencies and Expression Patterns of ACE2, TMPRSS2 and FURIN in Different Populations and Susceptibility to SARS-CoV-2
Authors: Tarek Mohammad , Abdelzaher Hana , Kobeissy Firas , El-Fawal Hassan A. N. , Salama Mohammed M. , Abdelnaser Anwar
Published: July 2021

The virus responsible for the COVID-19 global health crisis, SARS-CoV-2, has been shown to utilize the ACE2 protein as an entry point to its target cells. The virus has been shown to rely on the actions of TMPRSS2 (a serine protease), as well as FURIN (a peptidase), for the critical priming of its spike protein. It has been postulated that variations in the sequence and expression of SARS-CoV-2’s receptor (ACE2) and the two priming proteases (TMPRSS2 and FURIN) may be critical in contributing to SARS-CoV-2 infectivity. This study aims to examine the different expression levels of FURIN in various tissues and age ranges in light of ACE2 and TMPRSS2 expression levels using the LungMAP database. Furthermore, we retrieved expression quantitative trait loci (eQTLs) of the three genes and their annotation. We analyzed the frequency of the retrieved variants in data from various populations and compared it to the Egyptian population. We highlight FURIN’s potential interplay with the immune response to SARS-CoV-2 and showcase a myriad of variants of the three genes that are differentially expressed across populations. Our findings provide insights into potential genetic factors that impact SARS-CoV-2 infectivity in different populations and shed light on the varying expression patterns of FURIN.
Have We Taken Advantage of the Quarantine to Develop Healthy Habits? A Cross-Sectional Analysis of the Spanish COVID-19 Situation by Gender
Authors: Corbí Miguel , Del Líbano Mario , Alonso-Centeno Almudena , Gutiérrez-García Aida
Published: July 2021

The confinement caused by the COVID-19 pandemic led to changes in people’s lifestyles, which in part provided an opportunity to develop habits at home. The aims were: (1) to verify if the psychological well-being (PWB) of people related to healthy habits, and if physical activity (PA) and diet mediated this relationship; (2) to test if there were differences in this model of relationships between women and men; (3) to analyze if there were differences in healthy habits, PA, diet, and PWB depending on gender; (4) to test if there were differences in healthy habits, PA, diet, and PWB depending on living area; (5) and to assess if there were interaction effects of gender and living area in healthy habits, PA, diet, and PWB. Using a cross-sectional design, we obtained a sample of 1509 participants (18–78 years, 1020 women). Diet and PA fully mediated the relationship between PWB and healthy habits, and women developed more healthy habits than men, whereas men had higher levels of PA and PWB. We also found that people who lived in rural areas during confinement practiced more PA and had lower PWB levels than those who lived in urban areas. These results can help in the planning of strategies to promote healthy habits.
Relationship between Masticatory Function and Bone Mineral Density in Community-Dwelling Elderly: A Cross-Sectional Study
Authors: Ikebuchi Kumi , Matsuda Yuhei , Takeda Mayu , Takeda Miwako , Abe Takafumi , Tominaga Kazumichi , Yano Shozo , Isomura Minoru , Nabika Toru , Kanno Takahiro
Published: July 2021

The relationship between masticatory function and bone mineral density (BMD) is unclear. This cross-sectional study examined this relationship after adjusting for confounding factors. The subjects were 702 community-dwelling elderly adults (306 men, 396 women) who had been recruited for the Community-Based Healthcare Research and Education study in 2019. Objective masticatory function was assessed using the gummy jelly method. The median for each descriptive statistic was 69.0 years for age, 86.2% for the young adult mean, and 18.0 for masticatory function. Comparisons of the groups with good and poor masticatory function by sex revealed a significant difference in muscle mass and the tooth number for both sexes (p < 0.05). Men showed significant differences in age (p < 0.05) and salivary occult blood findings (p < 0.05). Multivariate analysis using propensity scores showed a significant association between masticatory function and BMD in both sexes (men: odds ratio 163.0, 95% confidence interval 1.36–19,610.55, p = 0.04; women: odds ratio 48.65, 95% confidence interval 1.52–1561.15, p = 0.03 in women). Masticatory function and BMD in the community-dwelling elderly may be related. However, other factors, including frailty and sarcopenia, may also be involved. Regular oral health care by dentists and dental hygienists may benefit this population.
Combined Effects of Unhealthy Lifestyle Behaviors on Metabolic Syndrome among Postmenopausal Women
Authors: Ra Jin-Suk , Kim Hyesun
Published: July 2021

This study aimed to identify the combined effects of unhealthy lifestyle behaviors, including diet, sedentary behavior, and physical activity on metabolic syndrome (MS) and components of MS among postmenopausal women. Secondary data analysis was conducted using the Korean National Health and Nutrition Examination Survey (2014–2018) with a cross-sectional study design. Logistic regression analysis was conducted with data from 6114 Korean postmenopausal women. While no significant effects of unhealthy lifestyle behaviors, either individually or as a combination, were found for MS, prolonged sedentary behavior without poor dietary behavior and insufficient physical activity was associated with increased likelihood of abdominal obesity (adjusted odds ratio [AOR]: 1.59, 95% confidence interval [CI]: 1.10–2.29) and impaired fasting glucose (AOR: 1.54, 95% CI: 1.13–2.10). The combination of poor dietary behavior and prolonged sedentary behaviors was also associated with increased likelihood of abdominal obesity (AOR: 1.48, 95% CI: 1.10–2.00) and impaired fasting glucose (AOR: 1.49, 95% CI: 1.14–1.96). In addition, prolonged sedentary behavior and insufficient physical activity together were associated with increased likelihood of abdominal obesity (AOR: 2.81, 95% CI: 1.90–4.20) and impaired fasting glucose (AOR: 1.59, 95% CI: 1.13–2.24). Finally, combining poor dietary behavior, prolonged sedentary behavior, and insufficient physical activity was also associated with increased likelihood of abdominal obesity (AOR: 2.05, 95% CI: 1.50–2.80) and impaired fasting glucose (AOR: 1.71, 95% CI: 1.32–2.23). Strategies for replacing sedentary behavior of postmenopausal women with activities are warranted for prevention of abdominal obesity and impaired fasting glucose.
Kinematic and Electrophysiological Characteristics of Pedal Operation by Elderly Drivers during Emergency Braking
Authors: Fujita Kazuki , Kobayashi Yasutaka , Sato Mamiko , Hori Hideaki , Sakai Ryo , Ogawa Tomoki , Sugano Tomonari , Kawabata Kaori , Hitosugi Masahito
Published: July 2021

Age-related decline in lower limb motor control may cause errors in pedal operation when driving a car. This study aimed to clarify the kinematics and electrophysiological characteristics of the pedal-switching operation associated with emergency braking in the case of elderly drivers. The participants in this study consisted of 11 young drivers and 10 elderly drivers. An experimental pedal was used, and the muscle activity and kinematic data during braking action were analyzed using the light from a light-emitting diode installed in the front as a trigger. The results showed that elderly drivers took the same time from viewing the visual stimulus to releasing the accelerator pedal as younger drivers, but took longer to switch to the brake pedal. The elderly drivers had higher soleus muscle activity throughout the process, from accelerator release to brake contact; furthermore, the rectus femoris activity was delayed, and the simultaneous activity between the rectus femoris and biceps femoris was low. Furthermore, elderly drivers tended to have low hip adduction velocity and tended to switch pedals by hip internal rotation. Thus, the alteration in joint movements and muscle activity of elderly drivers can reduce their pedal operability and may be related to the occurrence of pedal errors.
Risk Scoring System of Mortality and Prediction Model of Hospital Stay for Critically Ill Patients Receiving Parenteral Nutrition
Authors: Kim Jee-Yun , Yee Jeong , Park Tae-Im , Shin So-Youn , Ha Man-Ho , Gwak Hye-Sun
Published: July 2021

Predicting the clinical progression of intensive care unit (ICU) patients is crucial for survival and prognosis. Therefore, this retrospective study aimed to develop the risk scoring system of mortality and the prediction model of ICU length of stay (LOS) among patients admitted to the ICU. Data from ICU patients aged at least 18 years who received parenteral nutrition support for ≥50% of the daily calorie requirement from February 2014 to January 2018 were collected. In-hospital mortality and log-transformed LOS were analyzed by logistic regression and linear regression, respectively. For calculating risk scores, each coefficient was obtained based on regression model. Of 445 patients, 97 patients died in the ICU; the observed mortality rate was 21.8%. Using logistic regression analysis, APACHE II score (15–29: 1 point, 30 or higher: 2 points), qSOFA score ≥ 2 (2 points), serum albumin level < 3.4 g/dL (1 point), and infectious or respiratory disease (1 point) were incorporated into risk scoring system for mortality; patients with 0, 1, 2–4, and 5–6 points had approximately 10%, 20%, 40%, and 65% risk of death. For LOS, linear regression analysis showed the following prediction equation: log(LOS) = 0.01 × (APACHE II) + 0.04 × (total bilirubin) − 0.09 × (admission diagnosis of gastrointestinal disease or injury, poisoning, or other external cause) + 0.970. Our study provides the mortality risk score and LOS prediction equation. It could help clinicians to identify those at risk and optimize ICU management.
Using Design Thinking Principles to Improve Outpatients’ Experiences in Hospital Pharmacies: A Case Study of Two Hospitals in Asir Region, Saudi Arabia
Authors: Almaghaslah Dalia , Alsayari Abdulrhman , Alyahya Saleh Ali , Alshehri Rana , Alqadi Khawlah , Alasmari Sumiah
Published: July 2021

Introduction: Design thinking, an innovative problem-solving approach, has gained wide popularity in healthcare disciplines. The aim of this work is to improve outpatients’ experiences in hospital pharmacies in two hospitals in Asir region, Saudi Arabia. Methods: The design thinking approach, adopted from Stanford University’s D-School, was used in this study. Results: Several problems were identified: lack of comfortable environment in the pharmacies’ waiting area, lack of a queue management system, and workflow inefficiencies related to ordering and supplies of medicines. A prototype was proposed to overcome these challenges. Discussion and Conclusion: The design thinking approach helped in identifying end-user (patients visiting outpatient pharmacies) values and desires and provided an understanding of their struggles. It also proposed tailored solutions that could improve patients’ experiences while using the services of the outpatient pharmacies.
Photosynthetic and Ultrastructural Properties of Eggplant (Solanum melongena) under Salinity Stress
Authors: Alkhatib Rami , Abdo Nour , Mheidat Maha
Published: July 2021

Salinity is one of the major problems facing crops worldwide. Salinity can severely affect plants in a negative manner. This study aimed to evaluate the impact of NaCl on morpho–physiological, biochemical, structural and ultrastructural properties in Solanum melongena seedlings under different NaCl concentrations. Plants treated with high concentrations of NaCl showed a nonsignificant decrease in shoot height compared to the controls. However, NaCl concentration of 50 mM and above significantly decreased leaf area, while 75 mM and above significantly reduced the photosynthetic rate (PN) and leaf total sugar content when compared with plants treated with less-concentrated NaCl and the controls. Thick root sections from plants grown in 100 and 150 mM NaCl exhibit severe deformation in the epidermal and cortical layers. Additionally, TEM micrographs of plants treated with 75, 100, and 150 mM exhibited bulgy chloroplasts with loss of integrity thylakoid membranes associated with large starch grains. The changes in plant ultrastructure observed in this study broaden our knowledge about the impact of salinity at the cellular level.
Development of Frozen Pulps and Powders from Carrot and Tomato by-Products: Impact of Processing and Storage Time on Bioactive and Biological Properties
Authors: Araújo-Rodrigues Helena , Santos Diva , Campos Débora A. , Ratinho Modesta , M. Rodrigues Ivo , E. Pintado Manuela
Published: July 2021

Vegetables and fruits have an interesting nutritional profile, rich in bioactive metabolites, holding a high antioxidant potential and health associated benefits. However, their functional properties, the shorter shelf-life due to their high-water content, and their seasonality nature lead to extensive food losses and waste. The valorization of vegetables and fruits by-products through the development of value-added products and the application of preservation methods is of utmost importance to prevent food losses and waste. In this study, based on a circular economy approach, pulps and powders of baby carrot and cherry tomato by-products were prepared. Freezing, hot air drying and storage time impact on antioxidant activity and bioactive compounds were studied. Microbiological quality and pulps viscosity were also monitored for 6 months. During the freezing storage, TPC and antioxidant capacity by ABTS and ORAC assays decreased. The antioxidant capacity by DPPH method and carotenoid content increased during the first months of freezing, but then decreased. The drying process negatively affected the antioxidant capacity as well as carotenoid and polyphenolic content compared with the fresh vegetables. Both processing methodologies positively impacted the vitamin E content. During drying storage, there were no key variations in antioxidant capacity and bioactive content.
Simplified Interception/Evaporation Model
Authors: Baiamonte Giorgio
Published: July 2021

It is known that at the event scale, evaporation losses of rainfall intercepted by canopy are a few millimeters, which is often not much in comparison to other stocks in the water balance. Nevertheless, at yearly scale, the number of times that the canopy is filled by rainfall and then depleted can be so large that the interception flux may become an important fraction of rainfall. Many accurate interception models and models that describe evaporation by wet canopy have been proposed. However, they often require parameters that are difficult to obtain, especially for large-scale applications. In this paper, a simplified interception/evaporation model is proposed, which considers a modified Merrian model to compute interception during wet spells, and a simple power-law equation to model evaporation by wet canopy during dry spells. Thus, the model can be applied for continuous simulation, according to the sub hourly rainfall data that is appropriate to study both processes. It is shown that the Merrian model can be derived according to a simple linear storage model, also accounting for the antecedent intercepted stored volume, which is useful to consider for the suggested simplified approach. For faba bean cover crop, an application of the suggested procedure, providing reasonable results, is performed and discussed.
Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment
Authors: Hörnsten Jonas , Axelsson Louise , Westling Katarina
Published: July 2021

Background: The aim of the study was to examine the treatment outcome for patients with cardiovascular implantable electronic device (CIED) infections after extraction. Methods: Patients who underwent CIED extractions due to an infection at Karolinska University Hospital 2006–2015 were analyzed. Results: In total, 165 patients were reviewed, 104 (63%) with pocket infection and 61 (37%) with systemic infection. Of the patients with systemic infection, 34 and 25 patients fulfilled the criteria for definite and possible endocarditis, respectively. Complications after extraction occurred only in one patient. Reimplantation was made after a mean of 9.5 days and performed in 81% of those with pocket infection and 44.3% in systemic infection. Infection with the new device occurred in 4.6%. The mean length of hospital stay for patients with pocket infection was 5.7 days, compared to 38.6 days in systemic infection. One-year mortality was 7.7% and 22.2% in pocket infection and systemic infection, respectively. Patients with Staphylococcus aureus infection had a higher mortality. Conclusions: In this study, the majority of the patients had a pocket CIED infection, with a short hospital stay. Patients with a systemic infection, and S. aureus etiology, had a prolonged hospital stay and a higher mortality.
Spatio-Temporal Analysis of Influenza-Like Illness and Prediction of Incidence in High-Risk Regions in the United States from 2011 to 2020
Authors: Song Zhijuan , Jia Xiaocan , Bao Junzhe , Yang Yongli , Zhu Huili , Shi Xuezhong
Published: July 2021

About 8% of the Americans contract influenza during an average season according to the Centers for Disease Control and Prevention in the United States. It is necessary to strengthen the early warning for influenza and the prediction of public health. In this study, Spatial autocorrelation analysis and spatial scanning analysis were used to identify the spatiotemporal patterns of influenza-like illness (ILI) prevalence in the United States, during the 2011–2020 transmission seasons. A seasonal autoregressive integrated moving average (SARIMA) model was constructed to predict the influenza incidence of high-risk states. We found the highest incidence of ILI was mainly concentrated in the states of Louisiana, District of Columbia and Virginia. Mississippi was a high-risk state with a higher influenza incidence, and exhibited a high-high cluster with neighboring states. A SARIMA (1, 0, 0) (1, 1, 0)52 model was suitable for forecasting the ILI incidence of Mississippi. The relative errors between actual values and predicted values indicated that the predicted values matched the actual values well. Influenza is still an important health problem in the United States. The spread of ILI varies by season and geographical region. The peak season of influenza was the winter and spring, and the states with higher influenza rates are concentrated in the southeast. Increased surveillance in high-risk states could help control the spread of the influenza.
A Novel Fire Risk Assessment Approach for Large-Scale Commercial and High-Rise Buildings Based on Fuzzy Analytic Hierarchy Process (FAHP) and Coupling Revision
Authors: Wang Yijie , Hou Linzao , Li Mian , Zheng Ruixiang
Published: July 2021

In recent years, much more emphasis than before has been placed on fire safety regulations by the local and central authorities of China, which makes fire risk assessments more important. In this paper we propose a new fire risk assessment approach for large-scale commercial and high-rise buildings that aims to evaluate the performances of their fire safety systems; this should improve the fire risk management and public safety in those buildings. According to the features of large-scale commercial and high-rise buildings, a fire-risk indexing system was built, and based on it we established a scientific fire risk evaluation system. To this end, the fuzzy analytic hierarchy process (FAHP) was used to assign a reasonable weight to each fire risk factor in the evaluation system. In addition, we revised the original scores by analyzing the coupling relationships among the fire risk factors. To validate our system, we selected 11 buildings in Shandong province and collected their fire safety data. Then, we calculated the final scores for the fire safety management of those buildings, and the results show that: (1) our fire risk evaluation system can assign reasonable weights; (2) the proposed evaluation system is comprehensive and has strong interpretability, since it exploits the coupling relationships among the risk factors. The novelty of the proposed approach lies in that it integrates opinions from multiple experts and utilizes coupling relationships among the factors. Further, the feedback from the approach can find not only the weaknesses in fire risk management, but also the potential causes of fires. As a result, the feedback from our assessment can assist the safety chiefs and inspectors with improving fire risk management.
Neighborhood Characteristics and Cancer Survivorship: An Overview of the Current Literature on Neighborhood Landscapes and Cancer Care
Authors: Namin Sima , Zhou Yuhong , Neuner Joan , Beyer Kirsten
Published: July 2021

There is a growing literature on the association between neighborhood contexts and cancer survivorship. To understand the current trends and the gaps in the literature, we aimed to answer the following questions: To what degree, and how, has cancer survivorship research accounted for neighborhood-level effects? What neighborhood metrics have been used to operationalize neighborhood factors? To what degree do the neighborhood level metrics considered in cancer research reflect neighborhood development as identified in the Leadership for Energy and Environmental Design for Neighborhood Development (LEED-ND) guidelines? We first conducted a review guided by PRISMA extension for scoping review of the extant literature on neighborhood effects and cancer survivorship outcomes from January 2000 to January 2021. Second, we categorized the studied neighborhood metrics under six main themes. Third, we assessed the findings based on the LEED-ND guidelines to identify the most relevant neighborhood metrics in association with areas of focus in cancer survivorship care and research. The search results were scoped to 291 relevant peer-reviewed journal articles. Results show that survivorship disparities, primary care, and weight management are the main themes in the literature. Additionally, most articles rely on neighborhood SES as the primary (or only) examined neighborhood level metric. We argue that the expansion of interdisciplinary research to include neighborhood metrics endorsed by current paradigms in salutogenic urban design can enhance the understanding of the role of socioecological context in survivorship care and outcomes.
The Challenges of Partnering to Promote Health through Sport
Authors: Donaldson Alex , Staley Kiera , Cameron Matthew , Dowling Sarah , Randle Erica , O’Halloran Paul , McNeil Nicola , Stukas Arthur , Nicholson Matthew
Published: July 2021

Interagency partnerships and collaborations underpin a settings-based approach to health promotion in all settings, including sport. This study used an online concept mapping approach to explore the challenges that Regional Sports Assemblies (RSAs) in Victoria, Australia experienced when working in partnerships to develop and deliver physical activity programs in a community sport context. Participants from nine RSAs brainstormed 46 unique partnership-related challenges that they then sorted into groups based on similarity of meaning and rated for importance and capacity to manage (6-point scale; 0 = least, 5 = most). A six cluster map (number of statements in cluster, mean cluster importance and capacity ratings)—Co-design for regional areas (4, 4.22, 2.51); Financial resources (3, 4.00, 2.32); Localised delivery challenges (4, 3.72, 2.33); Challenges implementing existing State Sporting Association (SSA) products (9, 3.58, 2.23); Working with clubs (8, 3.43, 2.99); and Partnership engagement (18, 3.23, 2.95)—was considered the most appropriate interpretation of the sorted data. The most important challenge was Lack of volunteer time (4.56). Partnerships to implement health promotion initiatives in sports settings involve multiple challenges, particularly for regional sport organisations working in partnership with community sport clubs with limited human and financial resources, to implement programs developed by national or state-based organisations.
Thriving from Work: Conceptualization and Measurement
Authors: Peters Susan E. , Sorensen Glorian , Katz Jeffrey N. , Gundersen Daniel A. , Wagner Gregory R.
Published: July 2021

Work is a major contributor to our health and well-being. Workers’ thriving is directly influenced by their job design, work environment and organization. The purpose of this report is to describe the qualitative methods used to develop the candidate items for a novel measure of Thriving from Work through a multi-step iterative process including: a literature review, workshop, interviews with experts, and cognitive testing of the candidate items. Through this process, we defined Thriving from Work as the state of positive mental, physical, and social functioning in which workers’ experiences of their work and working conditions enable them to thrive in their overall lives, contributing to their ability to achieve their full potential in their work, home, and community. Thriving from Work was conceptualized into 37 attributes across seven dimensions: psychological, emotional, social, work–life integration, basic needs, experience of work, and health. We ultimately identified, developed and/or modified 87 candidate questionnaire items mapped to these attributes that performed well in cognitive testing in demographically and occupationally diverse workers. The Thriving from Work Questionnaire will be subjected to psychometric testing and item reduction in future studies. Individual items demonstrated face validity and good cognitive response properties and may be used independently from the questionnaire.
Impact of Climate Change on Eye Diseases and Associated Economical Costs
Authors: Echevarría-Lucas Lucía , Senciales-González José Mᵃ , Medialdea-Hurtado María Eloísa , Rodrigo-Comino Jesús
Published: July 2021

Climate change generates negative impacts on human health. However, little is known about specific impacts on eye diseases, especially in arid and semi-arid areas where increases in air temperatures are expected. Therefore, the main goals of this research are: (i) to highlight the association between common eye diseases and environmental factors; and (ii) to analyze, through the available literature, the health expenditure involved in combating these diseases and the savings from mitigating the environmental factors that aggravate them. Mixed methods were used to assess the cross-variables (environmental factors, eye diseases, health costs). Considering Southern Spain as an example, our results showed that areas with similar climatic conditions could increase eye diseases due to a sustained increase in temperatures and torrential rains, among other factors. We highlight that an increase in eye diseases in Southern Spain is conditioned by the effects of climate change by up to 36.5%; the economic burden of the main eye diseases, extrapolated to the rest of the country, would represent an annual burden of 0.7% of Spain’s Gross Domestic Product. In conclusion, the increase in eye diseases has a strong economic and social impact that could be reduced with proper management of the effects of climate change. We propose a new concept: disease sink, defined as any climate change mitigation action which reduces the incidence or morbidity of disease.
Fall-Related Activity Avoidance among Persons with Late Effects of Polio and Its Influence on Daily Life: A Mixed-Methods Study
Authors: Brogårdh Christina , Lexell Jan , Hammarlund Catharina Sjödahl
Published: July 2021

Falls are common among persons with late effects of polio (LEoP), which may lead to fear of falling and activity avoidance in everyday life. Here, we assessed the occurrence of fall-related activity avoidance among persons with LEoP and explored how these experiences influenced daily life. Fourteen ambulatory persons (seven women; mean age 70 years) with LEoP participated. They responded to the modified Survey of Activities and Fear of Falling in the Elderly (mSAFFE) and participated in individual interviews, which were analysed by systematic text condensation. Each quotation was deductively analysed from its representation with regard to mSAFFE. We found that many persons often avoided activities related to standing and walking, for example, taking a bath, performing household chores, walking outdoors, attending social events if there were stairs in the building and travelling by public transport, due to fear of falling, increased pain and fatigability. To facilitate the performance of daily activities participants expressed that strategic thinking and aids were important to use. In conclusion, fall-related activity avoidance is common in persons with LEoP, which negatively influence daily life and social participation. To increase daily functioning in this population, fall-related activity avoidance should be included in a multifaceted fall management program.
Preterm Labor Using Tocolysis as a Possible Risk Factor for Postpartum Depression: A 14-Year Population-Based Study in Taiwan
Authors: Liu Jui-Ming , Liu Chien-Yu , Hsu Ren-Jun , Chang Fung-Wei
Published: July 2021

Postpartum depression (PPD) is associated with negative physical and mental health outcomes for the mother and infant. Women often experience elevated symptoms of PPD, and the incidence of PPD has increased in recent years. There were lack of studies to investigate the effects of medications during pregnancy. Herein, we focused on the most common obstetric medical therapies used in labor and determined whether the medical therapies cause mental stress in pregnant women. This 14-year retrospective population-based nationwide study was based on the National Health Insurance Research Database. Univariate and multivariate logistic regression analyses were used to evaluate unadjusted and adjusted odds ratios and 95% confidence intervals for each tocolytic and uterotonic treatments during pregnancy and common medical illnesses. In comparing the effects of tocolytic and uterotonic medications on maternal PPD, tocolysis with the injection form of ritodrine resulted in a significantly higher risk of PPD based on multivariate analysis. This study supports existing research demonstrating an association between tocolysis with ritodrine and PPD. Ritodrine treatment for preterm labor was a significant risk factor for PPD, especially the injection form. This information provides obstetricians and health policy providers to pay attention to maternal mental health outcomes among high-risk pregnant women.
Lonely in the City–Sociodemographic Status and Somatic Morbidities as Predictors of Loneliness and Depression among Seniors–Preliminary Results
Authors: Sipowicz Kasper , Podlecka Marlena , Mokros Łukasz , Pietras Tadeusz
Published: July 2021

Up to a third of the population of older adults has been estimated to suffer from feelings of loneliness, which is considered a risk factor of depression. The aim of this paper is to compare the perceived level of loneliness and depression in seniors living in the country and in the cities and assess somatic morbidity and sociodemographic status as predictors of loneliness and depressiveness. n = 92 older adults in primary care units filled out a set of questionnaires: authors’ survey on sociodemographic data and morbidities, Beck Depression Inventory II (BDI, to measure depressiveness) and De Jong Gierveld Loneliness Scale (DJGLS, to assess loneliness). There was a strong, positive and statistically significant correlation between the BDI and DJGLS scores (R = 0.855, p < 0.001). City residents had on average higher BDI and DJGLS scores. Linear regression models were constructed to predict BDI and DJGLS scores. The set of statistically significant predictors were similar for BDI and DJGLS. Sociodemographic status and somatic morbidities accounted for around 90% of variance of depressiveness and loneliness scores in the studied group. Living alone was found to be the strongest relative predictor of both loneliness and depressiveness in the studied sample of the older adults. Our current results suggest that there might be a need to improve social support in the late adulthood as an intervention to diminish the sense of loneliness and depressiveness.
Effects of Gadolinium Deposits in the Cerebellum: Reviewing the Literature from In Vitro Laboratory Studies to In Vivo Human Investigations
Authors: Khairinisa Miski Aghnia , Ariyani Winda , Tsushima Yoshito , Koibuchi Noriyuki
Published: July 2021

Gadolinium (Gd)-based contrast agents (GBCAs) are chemicals injected intravenously during magnetic resonance imaging (MRI) to enhance the diagnostic yield. The repeated use of GBCAs can cause their deposition in the brain, including the cerebellum. Such deposition may affect various cell subsets in the brain and consequently cause behavioral alterations due to neurotoxicity. Caution should thus be exercised in using these agents, particularly in patients who are more likely to have repeated enhanced MRIs during their lifespan. Further studies are required to clarify the toxicity of GBCAs, and potential mechanisms causing neurotoxicity have recently been reported. This review introduces the effects of GBCAs in the cerebellum obtained from in vitro and in vivo studies and considers the possible mechanisms of neurotoxicity involved.
Hand-Wrist Disorders in Chainsaw Operators: A Follow-Up Study in a Group of Italian Loggers
Authors: Masci Federica , Spatari Giovanna , Giorgianni Concetto Mario , Pernigotti Elisa , Antonangeli Laura Maria , Bordoni Vittorio , Magenta Biasina Alberto , Pietrogrande Luca , Colosio Claudio
Published: July 2021

Despite the mechanization process implemented in arboriculture, logging tasks are still manually performed by chainsaw operators, which therefore are exposed to the risk of developing hand-wrist musculoskeletal disorders. Our research aimed to: (a) define whether the slight changes observed in 2017 showed an evolution to overt diseases; (b) study some risk determinants for these diseases such as age, working experience, and performing a secondary job. We recruited in a two-year follow-up study, 38 male forestry workers performing logging tasks employed in the Sicilian Forestry Department located in Enna. All the subjects underwent: (1) personal data collection; (2) administration of questionnaire addressed at upper limbs symptoms with a hand chart; (3) physical examination of the upper limbs, including Tinel’s and Phalen’s maneuvers; (4) ultrasound investigation of the hand-wrist area. In the two-year follow-up study we registered an overall increasing in wrist disorders, thus we can assume that forestry workers may be a target population for wrist diseases and deserve a particular attention in workers’ health surveillance programs. Interestingly, the prevalence of wrist-hand disorders resulted to be higher in younger workers.
Compassion Satisfaction, Secondary Traumatic Stress, and Burnout among Nurses Working in Trauma Centers: A Cross-Sectional Study
Authors: Lee Hyoung Ju , Lee Miyoung , Jang Sun Joo
Published: July 2021

Due to the nature of their work, trauma nurses are exposed to traumatic situations and often experience burnout. We conducted a cross-sectional study examining compassion satisfaction, secondary traumatic stress, and burnout among trauma nurses to identify the predictors of burnout. Data were collected from 219 nurses in four trauma centers in South Korea from July to August 2019. We used the Traumatic Events Inventory to measure nurses’ traumatic experience and three Professional Quality of Life subscales to measure compassion satisfaction, secondary traumatic stress, and burnout. Multiple regression analysis confirmed that compassion satisfaction and secondary traumatic stress significantly predicted nurses’ burnout, with compassion satisfaction being the most potent predictor. The regression model explained 59.2% of the variance. Nurses with high job satisfaction, high compassion satisfaction, and low secondary traumatic stress tend to experience less burnout than their counterparts. Nurse managers should recognize that strategies to enhance job and compassion satisfaction and decrease secondary traumatic stress are required to decrease burnout among nurses in trauma centers.
How Do Networks Reflect Collaborative Governance? The Case of a Sport Policy Program
Authors: Lehtonen Kati , Uusikylä Petri
Published: July 2021

This study examines the extent to which collaborative governance thinking is realized in a government-funded sport policy program. Our main argument is that this conversion requires the analysis and interpretation of meso-governance and related networks. In the analysis of meso-level sports policy governance networks, we apply social network analysis and theme interviews. The empirical analysis conducted in this study involves the network-based structure of the Finnish Schools on the Move (FSM) program, which was implemented in Finland from 2009 to 2018. Our research questions are as follows: (1) How have the nature and network structure of the program changed throughout the implementation of the program? (2) How is the collaborative governance thinking reflected in the design and implementation of the FSM program? This study shows that the network is the most significant intermediary structure at the policy and organizational levels. Particularly, it was important in the start-up phase of the program, when the main task of the network was to bring together different actors and to generate a common vision. By the end of the program’s funding, the structure of the network became centralized, with decreasing density. However, the analysis shows that collaborative governance thinking is mainly reflected in implementation, rather than in the genuine joint planning of activities.
“You Can’t Work with My People If You Don’t Know How to”: Enhancing Transfer of Care from Hospital to Primary Care for Aboriginal Australians with Chronic Disease
Authors: Blignault Ilse , Norsa Liz , Blackburn Raylene , Bloomfield George , Beetson Karen , Jalaludin Bin , Jones Nathan
Published: July 2021

Indigenous Australians experience significantly poorer health compared to other Australians, with chronic disease contributing to two-thirds of the health gap. We report on an evaluation of an innovative model that leverages mainstream and Aboriginal health resources to enable safe, supported transfer of care for Aboriginal adults with chronic conditions leaving hospital. The multisite evaluation was Aboriginal-led and underpinned by the principles of self-determination and equity and Indigenous research protocols. The qualitative study documented processes and captured service user and provider experiences. We found benefits for patients and their families, the hospital and the health system. The new model enhanced the patient journey and trust in the health service and was a source of staff satisfaction. Challenges included staff availability, patient identification and complexity and the broader issue of cultural safety. Critical success factors included strong governance with joint cultural and clinical leadership and enduring relationships and partnerships at the service delivery, organisation and system levels. A holistic model of care, bringing together cultural and clinical expertise and partnering with Indigenous community organisations, can enhance care coordination and safety across the hospital–community interface. It is important to consider context as well as specific program elements in design, implementation and evaluation.
Alterations in Circulating MicroRNAs and the Relation of MicroRNAs to Maximal Oxygen Consumption and Intima–Media Thickness in Ultra-Marathon Runners
Authors: Eyileten Ceren , Fitas Alex , Jakubik Daniel , Czajka Pamela , Mróz Anna , Czajkowska Anna , Witek Katarzyna , Bakalarski Wawrzyniec , De Rosa Salvatore , Postuła Marek , Małek Łukasz
Published: July 2021

The impact of long-term training on cardiovascular disease (CVD) is not clear. Carotid intima–media thickness (CIMT) test is recommended as a useful measure to diagnose the early stages of atherosclerosis. MicroRNAs (miRNAs) are altered due to endurance exercise and can be promising biomarkers of pathophysiological changes. We aimed to evaluate the association of circulating miRNAs with physical fitness and markers of atherosclerosis in ultra-marathon runners. Ultra-marathon runners had 28-fold upregulation of miR-125a-5p expressions compared to control individuals (p = 0.002), whereas let-7e and miR-126 did not differ statistically between ultra-marathon runners and controls. In the ultra-marathon runners’ group, negative correlations were observed between VO2max/kg and relative expression of miR-125a-5p and miR-126 (r = −0.402, p = 0.028; r = −0.438, p = 0.032, respectively). Positive correlations were observed between CIMT and miR-125a-5p and miR-126 (r = 0.388, p = 0.050; r = 0.504, p = 0.023, respectively) in ultra-marathon runners. Individuals with the highest quartile of VO2max/kg had 23-fold lower miR-126 expression in comparison to subgroups with lower VO2max/kg (p = 0.017). Our results may indicate that both miRNAs may serve as a biomarker for early pathological changes leading to atherosclerosis burden in athletes. Furthermore, the association between miRNAs and traditional risk factors for CVD indicate a possible use of these molecules as early biomarkers of future cardiovascular health.