bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Emergency Department Patient-Physician Conversation Through an Artificial Intelligence Symptom-Taking Tool: Mixed Methods Pilot Observational Study (Preprint)
Authors: Scheder-Bieschin Justus , Blümke Bibiana , de Buijzer Erwin , Cotte Fabienne , Echterdiek Fabian , Nacsa Júlia , Ondresik Marta , Ott Matthias , Paul Gregor , Schilling Tobias , Schmitt Anne , Wicks Paul , Gilbert Stephen
Published: March 2021

BACKGROUND

Establishing rapport and empathy between patients and their health care provider is important but challenging in the context of a busy and crowded emergency department (ED).

OBJECTIVE

We explore the hypotheses that rapport building, documentation, and time efficiency might be improved in the ED by providing patients a digital tool that uses Bayesian reasoning–based techniques to gather relevant symptoms and history for handover to clinicians.

METHODS

A 2-phase pilot evaluation was carried out in the ED of a German tertiary referral and major trauma hospital that treats an average of 120 patients daily. Phase 1 observations guided iterative improvement of the digital tool, which was then further evaluated in phase 2. All patients who were willing and able to provide consent were invited to participate, excluding those with severe injury or illness requiring immediate treatment, with traumatic injury, incapable of completing a health assessment, and aged <18 years. Over an 18-day period with 1699 patients presenting to the ED, 815 (47.96%) were eligible based on triage level. With available recruitment staff, 135 were approached, of whom 81 (60%) were included in the study. In a mixed methods evaluation, patients entered information into the tool, accessed by clinicians through a dashboard. All users completed evaluation Likert-scale questionnaires rating the tool’s performance. The feasibility of a larger trial was evaluated through rates of recruitment and questionnaire completion.

RESULTS

Respondents strongly endorsed the tool for facilitating conversation (61/81, 75% of patients, 57/78, 73% of physician ratings, and 10/10, 100% of nurse ratings). Most nurses judged the tool as potentially time saving, whereas most physicians only agreed for a subset of medical specialties (eg, surgery). Patients reported high usability and understood the tool’s questions. The tool was recommended by most patients (63/81, 78%), in 53% (41/77) of physician ratings, and in 76% (61/80) of nurse ratings. Questionnaire completion rates were 100% (81/81) by patients and 96% (78/81 enrolled patients) by physicians.

CONCLUSIONS

This pilot confirmed that a larger study in the setting would be feasible. The tool has clear potential to improve patient–health care provider interaction and could also contribute to ED efficiency savings. Future research and development will extend the range of patients for whom the history-taking tool has clinical utility.

CLINICALTRIAL

German Clinical Trials Register DRKS00024115; https://drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00024115
Adverse drug reaction analysis using statistical and machine learning methods: A systematic review (Preprint)
Authors: Park Yu Rang
Published: March 2021

UNSTRUCTURED

An adverse drug reaction (ADR) is an unintended response induced by a drug. It is important to determine the association between drugs and ADRs. There are many methods to demonstrate this association. This systematic review aimed to examine the analysis tools by considering original articles that introduced statistical and machine learning methods for predicting ADRs in humans. A systematic literature review of EMBASE and PubMed was conducted based on articles published from January 2015 to March 2020. The keywords were statistical, machine learning, and deep learning methods for the detection of ADR signals in the title and abstract. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement guidelines. In total, 72 articles were included in the current systematic review; of these, 51 and 21 addressed statistical and machine learning methods, respectively. This study provides a graphical overview of data-driven methods for detecting ADRs with multiple data sources for patient drug safety.
Telehealth Transition Assistance Program for Acute Spinal Cord Injury Caregivers: Protocol for a Mixed-Methods, Randomized Controlled Trial (Preprint)
Authors: Perrin Paul B , McDonald Scott D , Watson Jack D , Pierce Bradford S , Elliott Timothy R
Published: March 2021

BACKGROUND

While spinal cord injury (SCI) caregiving can be a rewarding experience, caregivers often experience reduced mental and physical health.

OBJECTIVE

This article describes the methodology of a study examining the efficacy of a newly developed telehealth Transition Assistance Program (TAP) for caregivers of individuals with acute SCI.

METHODS

A mixed-methods, randomized controlled trial is comparing TAP outcomes to that of a standard-of-care control. The study is recruiting for 48 months and incorporating both quantitative and qualitative outcome measures. Data are collected regarding barriers and facilitators to using the TAP, which might inform dissemination and implementation.

RESULTS

This study was funded by the Craig H. Neilsen Foundation in April 2017. It was approved by the institutional review boards at Virginia Commonwealth University and the Hunter Holmes McGuire Veterans Affairs Medical Center that same year. Participant recruitment and data collection began in 2018.

CONCLUSIONS

This study is implementing and testing an SCI caregiver intervention unlike any created before, targeting a critical time period that, until now, other SCI caregiver interventions have overlooked. Research personnel intend to disseminate the intervention and study findings through the publication of manuscripts and presentations at conferences. If the current study shows improvements in caregiver or patient well-being, the TAP for SCI caregivers could become part of the standard of care for acute SCI.

CLINICALTRIAL

ClinicalTrials.gov NCT03244098; https://www.clinicaltrials.gov/ct2/show/NCT03244098

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/28256
Efektifitas Cognitive Behavioural Therapy dengan Therapeutic Exercise Program pada Pencegahan Chronic Low Back Pain: Meta-analisis
Authors: Fadli Arif , Susilowati S. Th.
Published: March 2021

Latar Belakang: Nyeri menjadi keluhan utama seseorang mengunjungi fasilitas pelayanan kesehatan. Jumlah pasien Chronic Low Back Pain (CLBP) terus meningkat dan membutuhkan biaya perawatan kesehatan yang besar. Intervensi biomedis dianggap gagal menyelesaikan keluhan non-spesifik CLBP.Tujuan: Untuk meringkas data literatur yang ada mengenai efektivitas Cognitive Behavioural Therapy (CBT) dengan Therapeutic Exercise Program (TEP) dalam pencegahan CLBP.Metode: Systematic review dan meta-analisis studi Randomized Control Trial dari database Pubmed, Googlescholar, Willey Online Library, Research Gate, Science Direct. Analisis data menggunakan aplikasi Revman 5.3 dengan ukuran efek Cohen’s d.Hasil: Ada 6 studi yang dimasukkan dalam penelitian ini. Hasil analisis 6 studi CBT dengan TEP dibandingkan dengan TEP saja pada intensitas nyeri menunjukkan ukuran efek yang besar (d: -1,51; 95%CI: -2,75 s/d -0,27; p <0,00001). Untuk parameter skor kecacatan menunjukkan ukuran efek yang besar (d: -1,87; 95% CI: -3,11 s/d -0,62; p <0,00001).Kesimpulan: Intervensi CBT dengan TEP lebih efektif dari pada TEP saja dalam pencegahan CLBP. Efektivitas hasil pencegahan CLBP dipengaruhi oleh keberhasilan pasien dalam menyelesaikan program rehabilitasi.
Acute Kidney Injury among Black Patients with Sickle Cell Trait and Sickle Cell Disease
Authors: Olaniran Kabir O. , Allegretti Andrew S. , Zhao Sophia H. , Nigwekar Sagar U. , Kalim Sahir
Published: March 2021

Background and objectives

Sickle cell trait and sickle cell disease are associated with faster GFR decline compared with normal hemoglobin phenotypes. We sought to compare the AKI risk in sickle cell trait/disease to normal hemoglobin phenotypes and investigate the association between AKI and GFR decline in sickle cell trait/disease.

Design, setting, participants, & measurements

This multicenter observational study used registry data (January 2005–June 2018) of adult Black patients with sickle cell trait/disease (exposures) and normal hemoglobin phenotype (reference) ascertained by hemoglobin electrophoresis. Outcomes of interest (incident AKI [1.5 times baseline serum creatinine or higher], incident severe AKI [doubling of baseline serum creatinine or higher], and incident sustained AKI [AKI persisting for ≥72 hours]) were adjudicated by chart review and evaluated by Cox regression. The association between AKI and GFR decline (linear mixed models) was also investigated.

Results

We identified 8968 reference patients, 1279 patients with sickle cell trait, and 254 patients with sickle cell disease with a median follow-up of 7.6 years and mean baseline serum creatinine of 0.8 mg/dl. We observed 796 AKI events, 452 sustained AKI events, and 466 severe AKI events. Compared with people with a normal hemoglobin phenotype, sickle cell trait was associated with higher risk for sustained AKI (adjusted hazard ratio, 1.64; 95% confidence interval, 1.27 to 2.11), but not AKI (adjusted hazard ratio, 1.11; 95% confidence interval, 0.91 to 1.36) or severe AKI (adjusted hazard ratio, 1.26; 95% confidence interval, 0.96 to 1.64). Sickle cell disease was associated with AKI (adjusted hazard ratio, 2.85; 95% confidence interval, 2.13 to 3.81), severe AKI (adjusted hazard ratio, 2.38; 95% confidence interval, 1.65 to 3.42), and sustained AKI (adjusted hazard ratio, 2.50; 95% confidence interval, 1.68 to 3.71). Post-AKI GFR decline was significantly faster in sickle cell trait (0.37 ml/min per 1.73 m2 per year faster, P<0.01) and disease (1.69 ml/min per 1.73 m2 per year faster, P<0.01) compared with the reference.

Conclusions

Sickle cell trait and disease are associated with higher risk of AKI, which is associated with accelerated decline in eGFR.
Acute Kidney Injury, Microvascular Rarefaction, and Estimated Glomerular Filtration Rate in Kidney Transplant Recipients
Authors: Doreille Alice , Azzi Féryel , Larivière-Beaudoin Stéphanie , Karakeussian-Rimbaud Annie , Trudel Dominique , Hébert Marie-Josée , Dieudé Mélanie , Patey Natacha , Cardinal Héloïse
Published: March 2021

Background and objectives

Animal studies suggest that microvascular rarefaction is a key factor in the acute kidney disease to CKD transition. Hence, delayed graft function appears as a unique human model of AKI to further explore the role of microvascular rarefaction in kidney transplant recipients. Here, we assessed whether delayed graft function is associated with peritubular capillary loss and evaluated the association between this loss and long-term kidney graft function.

Design, setting, participants, & measurements

This observational, retrospective cohort study included 61 participants who experienced delayed graft function and 130 who had immediate graft function. We used linear regression models to evaluate associations between delayed graft function and peritubular capillary density expressed as the percentage of efficient cortical area occupied by peritubular capillaries in pre- and post-transplant graft biopsies. eGFRs 1 and 3 years post-transplant were secondary outcomes.

Results

Post-transplant biopsies were performed at a median of 113 days (interquartile range, 101–128) after transplantation. Peritubular capillary density went from 15.4% to 11.5% in patients with delayed graft function (median change, −3.7%; interquartile range, −6.6% to −0.8%) and from 19.7% to 15.1% in those with immediate graft function (median change, −4.5%; interquartile range, −8.0% to −0.8%). Although the unadjusted change in peritubular capillary density was similar between patients with and without delayed graft function, delayed graft function was associated with more peritubular capillary loss in the multivariable analysis (adjusted difference in change, −2.9%; 95% confidence interval, −4.0 to −1.8). Pretransplant peritubular capillary density and change in peritubular capillary density were associated with eGFR 1 and 3 years post-transplantation.

Conclusions

Perioperative AKI is associated with lower density in peritubular capillaries before transplantation and with loss of peritubular capillaries following transplantation. Lower peritubular capillary density is linked to lower long-term eGFR.
Cornerstones of ‘fair’ drug coverage: appropriate cost sharing and utilization management policies for pharmaceuticals
Authors: Pearson Steven D , Towse Adrian , Lowe Maria , Segel Celia S , Henshall Chris
Published: March 2021

At the heart of all health insurance programs lies ethical tension between maximizing the freedom of patients and clinicians to tailor care for the individual and the need to make healthcare affordable. Nowhere is this tension more fiercely debated than in benefit design and coverage policy for pharmaceuticals. This paper focuses on three areas over which there is the most controversy about how to judge whether drug coverage is appropriate: cost-sharing provisions, clinical eligibility criteria, and economic-step therapy and required switching. In each of these domains we present ‘ethical goals for access’ followed by a series of ‘fair design criteria’ that can be used by stakeholders to drive more transparent and accountable drug coverage.
Tinjauan Yuridis terhadap Dampak Eksploitasi Perdagangan Anak dengan Modus Perkawinan
Authors: Bagus Arya Bhaskara Anak Agung Ngurah , Gede Sugiartha I Nyoman , Diah Gayatri Sudibya
Published: March 2021

The main causes of sexual crimes are economic factors and a lack of formal education, which triggers the crime of sexual exploitation of child trafficking with the marriage mode, which usually targets mostly children or women. This study aims to determine the impact of the exploitation of child trafficking by means of marriage as seen from the aspects of the Law on Trafficking in Persons and to find out the sanctions against perpetrators of child trafficking with the mode of marriage that occur in Indonesia. This research uses the normative legal method. The results of the analysis show that the impact that can be had on children and women victims is the impact on physical and psychological, emotional, spiritual, and disturbed health. Then, sanctions against perpetrators are regulated in Article 297 contained in the Criminal Code and in Law Number 21 of 2007 concerning the Eradication of the Crime of Trafficking in Persons, Law Number 23 of 2002 Concerning Child Protection and also Law Number 13 concerning Manpower.
Pelaksanaan Eksekusi Benda Jaminan Kredit yang Tidak Mencukupi untuk Pelunasan Utang di Koperasi Guna Arta Karangasem
Authors: Wira Sanjaya I Gede Agus , Budiartha I Nyoman Putu , Arini Desak Gde Dwi
Published: March 2021

This study aims to determine the credit agreement or business loan between the customer and the cooperative and to find out the settlement in the event of a dispute in the credit agreement between the customer and the cooperative. This study uses empirical research methods where the method is based on positive law and norms. The results showed that the agreement made between the cooperative and the customer is based on the agreement of the parties who are ready to carry out their obligations and get rights. The obligation of the cooperative to provide loan funds to customers is the right of the cooperative to benefit from interest from customer loan funds. The obligation of the customer to pay the loan on time that has been agreed upon because he has lent funds, the right of the customer to get a loan for the customer's needs according to the agreement of the parties. Then, the agreement of the parties is not a guarantee that there will be no default, the importance of a legal attorney in an agreement makes it easier to resolve problems between the parties. Legal attorneys provide options for ending the case through the court (litigation) and settlement in a family way (non-litigation). Most parties use the non-litigation route because they want everything to be done quickly but at low cost. If the non-litigation solution does not find a middle ground, the case will proceed to court. Judge's rule applies to parties in litigation from the time until the costs incurred. Those who lost are willing to be asked for compensation for their actions.
Akibat Hukum Bagi Prajurit TNI Melakukan Tindak Pidana Desersi yang Diputus In Absentia dalam Praktek Pengadilan Militer Iii-14 Denpasar
Authors: KUSUMA PURWANTA I WAYAN , Dewi Anak Agung Sagung Laksmi , Karma Ni Made Sukaryati
Published: March 2021

The Republic of Indonesia is a State based on Law. Every Indonesian citizen is obedient and submissive to the law including Indonesian National Army Soldiers (TNI). Soldiers of  the Indonesian National Army besides submitting to general legal rules such as the Criminal Code (KUHP) and also subject to special rules that only apply to soldiers of the Indonesian National Army namely the Criminal Law Code Military (KUHPM) and Military Disciplinary Law  (KUHDM). Discipline is  a  basic  milestone for  Indonesian National Army  Soldiers in carrying out their duties. If a Indonesian National Army Soldiers lacks discipline in his life order it can be the cause of a crime. Based on this matter the following issues will be discussed (1) What are the factors that cause Indonesian National Army Soldiers to commit a crime of desertion (2) What is the legal consequence of the In Absentia ruling for Indonesian National Army Soldiers who commit a crime of desertion. The method used is a juridical- empirical research method. The results of the study stated that due to the In absentia law a Indonesian National Army Soldiers committing a Desertion criminal act would remain on trial without the presence of the defendant and be sentenced to prison with additional punishment in the form of dismissal from military service.
Perlindungan Hukum Terhadap Pengguna Jasa Angkutan Sewa Umum di Provinsi Bali
Authors: ANGGARA MADE BAYU , Sujana I Nyoman , Ujianti Ni Made Puspautari
Published: March 2021

Transportation of people using motorized vehicles is not on a route, which is further regulated by the Minister of Transportation Regulation No. 108 of 2017 concerning the Implementation of Transportation of People with Public Motor Vehicles not in a Route. In this study using normative legal methods, namely by examining library legal materials and secondary data. The regulation on consumer protection has been regulated in law number 8 0f 1999 concerning consumer protection, hereinafter referred to as UUPK. The purpose of this study was to determine the implementation of the implementation of public rental transportation in the Province of Bali and also to determine the legal protection of users of public rental services in the Province of Bali
NÓS POR NÓS MESMOS: EVIDÊNCIAS DA PRODUÇÃO ACADÊMICA SOBRE O EXAME NACIONAL DE DESEMPENHO DE ESTUDANTES (ENADE) EM CIÊNCIAS CONTÁBEIS
Authors: Pereira Antonio Gualberto , Nunes Tania , Simões Rafael Rocha
Published: March 2021

O presente estudo realizou uma revisão sistemática da produção acadêmica acerca do Exame Nacional de Desempenho de Estudantes na área de Contabilidade e, para tanto, explorou os seguintes objetivos específicos: (i) escanear os periódicos nacionais com maior classificação no Qualis – CAPES; (ii) analisar quantitativa e qualitativamente os artigos localizados, incluindo a verificação de indicadores bibliométricos propostos na literatura; (iii) sintetizar graficamente a evolução da produção sobre esse tópico no período. O método de análise foi descritivo e bibliométrico, abarcando mais de dez anos de produção acadêmica sobre o ENADE em periódicos nacionais, além de teses de doutorado em Ciências Contábeis.  Identificou-se um crescimento da produção sobre o ENADE nos últimos anos. Os achados referentes a indicadores bibliométricos específicos mostram que as Leis de Lotka, Bradford e Zipf são ratificadas. Ao final, é apresentado um quadro geral da produção acadêmica sobre o ENADE em mais de uma década, fornecendo indicativos de tendência para a pesquisa na área
La tutela del derecho a la salud mental en época de pandemia
Authors: Lozano Rodríguez Felipe , Muñoz Muñoz Cristian Fernán , González Martínez Enmanuel
Published: March 2021

El objetivo de la presente investigación es analizar la tutela como mecanismo de protección del derecho fundamental a la salud mental en época de pandemia de la COVID–19. La metodología utilizada es de tipo cualitativo, de carácter exploratorio. La investigación se encuentra segmentada en tres partes: diagnóstico jurídico del derecho a la salud mental; garantías y responsabilidad jurídica del Estado; prospectiva de la salud mental de cara a la responsabilidad jurídica del Estado. Finalmente, con el conjunto de estas consideraciones teóricas y prácticas, se llega a evidenciar la incapacidad del Estado colombiano para entender la COVID-19, durante y después del periodo de confinamiento, en relación con especificidad del área de salud mental. Se concluye que, aunque existe poca legislación durante la época de pandemia en salud mental, existe una legislación sólida anterior a la pandemia para garantizar la salvaguarda del derecho a la salud mental. La tutela es un mecanismo eficaz a la hora de la reclamación de los derechos, más aún desde la función jurídica digital que facilitaría los trámites en la pandemia.
Consultas populares: barreras institucionales y tensiones por la participación local
Authors: Montoya Giraldo Andrea , Villegas Murillo Johan Mauricio
Published: March 2021

Este artículo da cuenta de las controversias que se han suscitado en el plano jurídico y político en relación con la exploración y explotación minera en los municipios, y las barreras institucionales a las que se han visto enfrentados los ciudadanos en la utilización de este mecanismo de participación ciudadana en relación con temas mineros en los municipios de Pueblorrico (Antioquia), Cajamarca (Tolima) y Córdoba (Quindío). Para la construcción de los casos de estudio, se acudió al tipo de investigación cualitativa con enfoque sociojurídico y se utilizó la estrategia documental acompañada de visitas al territorio con aplicación de entrevistas a los actores involucrados en estos procesos, identificando que los ciudadanos efectivamente se enfrentaron a prácticas desplegadas desde lo institucional, que reflejan la vulneración de las garantías democráticas que el Estado tiene la obligación de proteger.
La lesión a los derechos de la personalidad en la jurisprudencia de la instancia de recurso especial brasileña
Authors: Fachetti Silvestre Gilberto , Figueira Marchiori Bruna
Published: March 2021

Esta investigación encontró divergencias en el establecimiento de la compensación pecuniaria (el quantum) de daño moral. En este sentido, el objetivo fue identificar si actualmente el Tribunal Superior de Justicia de Brasil exige probar el dolor o el sufrimiento para la ocurrencia de daño moral y para justificar la indemnización. Para esto, se realizaron estadísticas de juzgados con el objetivo de verificar si existe jurisprudencia sobre el tema. En este sentido, la investigación se desarrolló con enfoque cualicuantitativo (cualitativo y cuantitativo). Se realizó una revisión de la literatura para profundizar los conceptos teóricos y teorías respecto a este tema. La investigación adoptó la metodología de revisión sistemática de jurisprudencia y el método fue el inductivo. Se buscó establecer una referencia general basada en el conocimiento de cierto número de datos singulares para la elaboración de una conclusión genérica. Como resultado, la investigación ofrece la comprensión mayoritaria actual del Tribunal Superior de Justicia (STJ por sus siglas en portugués) sobre la no exigencia del elemento psíquico en las acciones de indemnización por daños morales.
Effect of silicon application on soil physical and chemical properties under drought stress
Authors:   Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah-21488, Saudi Arabia, Al-Ghamdi A.A.M. , Ashram A.M. ,   Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah-21488, Saudi Arabia
Published: March 2021

Aim: To study the effect of silicon application on soil properties under normal conditions and different levels of drought stress (75%, 50% and 25% field capacity). Methodology: Nigella sativa seeds were sown in pots filled with 5 kg of homogeneously mixed 2:1 ratio of sand to clay soil. Two set of plants were grown-one set was grown in soil without silicon treatment, and the other was treated with silicic acid (120 g kg-1 soil). For drought stress conditions, each set was subdivided into four sets, which were irrigated at 100% (control), 75%, 50%, and 25% field capacity. Dry soil samples were used to determine the inorganic content, including phosphorus, potassium, calcium, magnesium and iron. Results: The results showed that the concentration of soil minerals (phosphorus, potassium, calcium, magnesium, and iron) increased due to silicon treatment. However, this increase in mineral concentration was more pronounced at higher water levels (100%, 75% field capacity) in the case of potassium, calcium, and iron. Of note, the increase in phosphorus and magnesium concentration after silicon treatment was remarkable under higher stress conditions (50%, 25% field capacity). Interpretation: Overall, silicon application increased soil minerals and alleviated drought stress. Key words: Drought stress, Mineral ions, Nigella sativa, Silicic acid
POST-NIGERIAN CIVIL WAR COMMUNITY RECONSTRUCTION STRATEGIES IN (ANIOMA) WESTERN IGBOLAND, 1970-1991
Authors: Iweze Daniel Olisa , Anyanwu Uchenna
Published: March 2021

A Guerra Civil Nigeriana causou muita devastação em Igbolândia como um todo e as necessidades mais urgentes da população eram alimentação, vestuário e abrigo. Para enfrentar esses desafios, o governo nigeriano, sob o general Gowon, introduziu o programa de reconstrução pós-guerra civil para reconstruir Igbolândia. A reconstrução de Igbolândia ocidental, (Anioma) no estado do meio-oeste foi realizada pelo governo do estado do meio-oeste sob o coronel Ogbemudia. Os esforços dos governos federal e estadual do Meio-Oeste na reabilitação e reconstrução da infraestrutura social e econômica danificada em Anioma foram inadequados e isso obrigou a população a embarcar em intervenções de autoajuda individuais e comunitárias. Este artigo explora as verdadeiras estratégias de autoajuda que o povo adotou e afirma que os programas de reconstrução foram tímidos e sutilmente empacotados para marginalizar e dominar o povo igbo ocidental nos aspectos econômicos e políticos do Estado do Meio-Oeste e da Nigéria. O argumento geral do artigo é que foi a resiliência valorizada do povo que foi fundamental na reconstrução de suas comunidades devastadas pela guerra.
O chapéu do Teemo
Authors: Postali Thífani , Rodrigues Iuama Tadeu
Published: March 2021

O artigo apresenta uma reflexão sobre a produção de comunidades de jogadores do gênero MOBA (arena de batalha multijogador online), tendo a empresa Riot Games e o seu título League of Legends, como objeto de estudo. Para tanto, utiliza pesquisa bibliográfica em periódicos e considerações sobre um documentário específico sobre a empresa. A partir de teóricos como Huizinga e Caillois, que apresentam reflexões sobre jogos, e Martin Buber, Edgar Morin e Benedict Anderson, que abordam conceitos de comunidade, o trabalho aponta como a construção dessas comunidades gamers se aproxima da ideia de nação, sendo um produto arquitetado e, portanto, distante da ideia de comunidade buberiana.
MODELLING RAINFALL-RUNOFF PROCESS FOR SUB CATCHMENT OF NARMADA RIVER BASIN AT HOSHANGABAD USING SEMI DISTRIBUTED MODEL HBV
Authors: vats abhishek , Denis Derric
Published: March 2021

In this study, the light version of Hydrologiska Byrans
Vattenbalansavdelning hydrological model (HBV), has been used to
synthesize river discharge and daily flow series for twelve years in the
sub catchments of the Narmada river basin at Hoshangabad. The plain area
of Narmada river basin at Hoshangabad is used for this study,with a
drainage area of 10594 km2 and co-ordinates lies between 22°46’Nand
77°43’E.The model was run using twelve years data. Parametrization of
parameters were obtained after warming, calibration and validating the
results. There after the sensitivity analysis was done and acceptable
range for each parametrized parameter was obtained. The Coefficient of
Determination of observed and simulated discharge at the Hoshangabad was
found to be 0.84. In Narmada River Basin at Hoshangabad
hydrologicalmodeling using the HBV model, MAXBAS is the most sensitive
parameter. The sensitive parameters from high to low along with their
slopes values are Maxbas: 0.23, Alpha: 0.018, Fc: 0.012, K1:0.010, Beta:
0.008, K2: 0.005, Perc: 0.001 and Lp 0.001. The study shows that light
version of the HBV model can be used to model the runoff of the sub
catchment of the Narmada river basin at Hoshangabad.
The N-terminal domain of Spike protein contributes to antigenicity difference between porcine epidemic diarrhea virus genotypes G1 and G2
Authors: Qiao Qi-long , Li Ning , Song Ming-zhen , Chen Jing , Yang Pan pan , Miao Yu-he , ZHAO JUN
Published: March 2021

Porcine epidemic diarrhea virus (PEDV) strains have been clarified into
two genotypes, G1 and G2, based on the sequence of the spike (S) gene.
Amino acid mutations that distinguish the two PEDV genotypes were mostly
located in the N-terminal domain (NTD) (aa 1-380) of S protein. The fact
of increased outbreaks of G2 subtype PEDV and the failure of G1 subtype
PEDV strain (CV777)-based vaccine in China since 2010 suggested that
multiple amino acid mutations located in the NTD altered the
antigenicity of S protein. To determine the role of the NTD of S protein
in the antigenicity difference, the NTD of the CV777 vaccine strain (G1)
and CH/ZMDZY/11 strain (G2) was expressed in E. coli, respectively.
polyclonal antibodies (PAbs) against genotype-specific S proteins were
prepared by immunizing BALB/c mice using purified S proteins.
Antigenicity was systematically compared by detection of PAbs against
two genotype PEDV strains and purified S proteins using Western blot,
indirect enzyme-linked immunosorbent assay (ELISA), indirect
immunofluorescence assay (IFA), and serum cross-neutralization assay
(SN). Consistent with the multiple amino acid mutations in the NTD of S
protein, different antigenic cross-reactivity between the two genotypes
was demonstrated. There was six-fold and more than twenty-fold
difference in ELISA and SN titer between anti-CV777 S protein antibodies
against G1 and G2 subtype strains, respectively. There was twofold and
eight-fold difference in ELISA and SN titer between anti-ZMDZY S protein
antibodies against G1 and G2 genotype strains, respectively. The results
proved that the NTD of S protein contributes to the antigenicity
difference between PEDV genotypes G1 and G2, and highlighted a G2 strain
should be used to develop a vaccine for providing better protection
against prevalent genotype of PEDV.
Clinical analysis of peritonitis in peritoneal dialysis patients
Authors: Kovacevic Zoran , Cvetkovic Olivera , Janicijevic Katarina , Janicijevic-Petrovic Mirjana , Cvetkovic Mihailo , Zornic Nenad
Published: March 2021

Introduction/Objective. Peritoneal dialysis is a method of treating patients in the terminal phase of renal failure (end-stage renal disease). Peritonitis represents most severe and most common complication of peritoneal dialysis. The most common peritonitis causes are Gram negative microorganisms: Staphylococcus-coagulase-negative, Staphylococcus aureus, Streptococcus sp, Neisseria sp. Gram negative microorganisms are: Pseudomonas sp, Enterococcus, Klebsiella sp, Proteus sp, Acinetobacter sp. The aim of the study was to examine the incidence of peritonitis and to determine the differences between patients with and without peritonitis and catheter infection. Other goals of the work were: the most frequent causes of peritonitis, the outcome of treatment, the influence of the length of treatment on the development of peritonitis, the influence of the peritoneal dialysis adequacy on the development of peritonitis, the influence of anemia, nutritional status, iron status, secondary hyperparathyroidism (Ca, P, CaxPO4, parathormone), protein status ? albumin and the effect of acid uricum on the development of peritonitis. Methods. Retrospectively, 84 patients were analyzed of peritoneal dialysis (2012?2016) at the Kragujevac Center for Nephrology and Dialysis of Clinical Center. The diagnosis of peritonitis was based on clinical picture, biochemical analyses, leukocyte in sediment of dialysis, findings of peritoneal-culture, signs of inflammation (C-reactive protein, leukocytes). The analysis included: the most common causes, the outcome of treatment, the influence of the length of treatment, the influence of the peritoneal dialysis adequacy, the influence of anemia, the influence of iron status, the influence of secondary hyperparathyroidism, the influence of protein status - albumin, and the effect of acid uricum on the development of peritonitis. Results. In total, 22 patients had one, six patients had two, six patients had three, six patients more than three episodes of peritonitis. The difference in mean values of the number of erythrocytes, hemoglobin, hematocrit, iron, albumin, diastolic pressure, systolic pressure between patients with peritonitis, and those without it, were statistically significant (p < 0.05). The difference in mean values of calcium (Ca), phosphor (P), CaxPO4, uricum value, parathormone, peritoneal dialysis adequacy, systolic pressure was not statistically significant (p > 0.05). The incidence of peritonitis and death were not associated (p = 1.000). Conclusion, Peritonitis is severe complication of peritoneal dialysis. Anemia and nutritional status are risk factors that affect the development of peritonitis in patients on peritoneal dialysis.
Identifying Potential Intervention Points for Acute Hypoglycemic Events in Patients With Type 2 Diabetes Using Retrospective Clinical Data
Authors: Lacy Mary E. , Whitmer Rachel A. , Lee Sei J. , Rushakoff Robert J. , Pletcher Mark J.
Published: March 2021

This
retrospective study examined changes in medication orders as a risk factor for
future acute hypoglycemic events. The investigators identified factors
associated with acute hypoglycemic events resulting in emergency department visits
or inpatient admissions. Non-Hispanic Black race, chronic kidney disease,
insulin at baseline, and non-private insurance were associated with higher risk
of an acute hypoglycemic event, whereas age, sex, and A1C were not. After
adjustment for other risk factors, changes in insulin orders after A1C measurement
were associated with a 1.5 times higher risk of an acute hypoglycemia (adjusted
hazard ratio 1.48, 95% CI 1.08–2.03). These results further understanding of
risk factors and clinical processes relevant to predicting and preventing acute
hypoglycemia.
IMPLEMENTASI APLIKASI SISTEM INFORMASI DESA DAN KEPENDUDUKAN BERBASIS WEB DI DESA KUKUH KERAMBITAN
Authors: Parwita Wayan Gede Suka , Mutiarani Rizkita Ayu , Adnyana I Nyoman Widhi
Published: March 2021

Pengabdian masyarakat ini bertujuan untuk membantu aparatur pemerintahan desa mengimplementasikan Sistem Informasi Desa dan Kependudukan Berbasis Web di Desa Kukuh Kecamatan Kerambitan Kebupaten Tabanan. Pengabdian kepada masayarakat ini dipolakan dengan 3 (tiga) tahapan, yaitu 1) tahap pendaftaran Domain.desa.id ke Kementerian Komunikasi dan Informatika; 2) tahap penyiapan server & hosting dengan memanfaatkan jasa para vendor web hosting, serta 3) implementasi Sistem Informasi Desa dan Kependudukan. Pelaksanaan pengabdian ini dilakukakn dalam bentuk kegiatan partisipasif perguruan tinggi melalui pendekatan terhadap sumber daya yang ada di mitra pada Pemerintahan Desa Kukuh Kecamatan Kerambitan kabupaten tabanan. Bentuk kegiatan bertahap dan terdistribusi dalam 3 bulan.Kata kunci: Desa Kukuh, Sistem Informasi Desa
Crusted (Norwegian) Scabies and HTLV-1 Infection Association: A Case Report
Authors: Times de Carvalho Bernardo , Arcoverde Perrier Arthur , Maria Mirelle de Macedo e Silva Patricia , Roberto Cabral da Silva Joao
Published: March 2021

Crusted scabies, formerly known as Norwegian scabies is as uncommon presentation of scabies that may occur in the in association with an immunosuppressive status. The article aims to present a case report in which a male patient with HTLV-1 carrier status admitted for investigation of eczematous and crusted chronic skin lesions and submitted to a dermatologic evaluation and a skin biopsy considering the hypothesis of a cutaneous form of lymphoma associated with HTLV-1 infection had the diagnosis of Crusted scabies instead. There is data regarding de association of crusted scabies and Human T-lymphotropic virus type 1 (HTLV-1) chronic infection. Therefore, this important diagnosis should always be accessed specially in HTLV-1 endemic regions.
Potret Sosial Komunitas Anak Punk di Kota Perawang, Provinsi Riau
Authors: Fitria Yani Maisul , Putra Eka Vidya
Published: March 2021

Latar belakang penelitian ini bermula dari ketertarikan peneliti ketika melihat banyaknya remaja yang bergabung kedalam komunitas Punk. Penelitian ini bertujuan untuk mengetahui latar belakang sosial munculnya komunitas Punk di Kota Perawang. Teori yang digunakan dalam menganalisis penelitian ini adalah teori pembentukan kelompok yaitu Domisili Theory, Similar Attitude Theory, Activity Interaction Theory dan Practicality Theory. Penelitian ini menggunakan pendekatan penelitian kualitatif tipe studi kasus. Teknik pemilihan informan adalah pusposive sampling. Pengumpulan data dilakukan dengan cara observasi, wawancara dan studi dokumentasi. Hasil penelitian menunjukkan Hasil penelitian menemukan bahwa motivasi anak Punk bergabung ke dalam komunitas Punk disebabkan beberapa alasan-alasan seperti kesamaan hobi, ingin mencari kebebasan, teman sepermainan dan ekspresi diri. Hasil penelitian menemukan bahwa sejarah munculnya komunitas Punk di Kota Perawang dan negara di dunia relatif sama yaitu karena tekanan didalam masyarakat tetapi munculnya komunitas Punk di negara di dunia karena adanya tekanan politik sedangkan munculnya komunitas Punk di Kota Perawang karena adanya tekanan sosial. Maka ditemukan latar belakang sosial munculnya komunitas Punk di Kota Perawang karena menginginkan kebebasan, ekspresi diri, faktor pertemanan dan kesamaan hobi.
Covid-19: A strife of interests for us all and what problem are we attempting to solve?
Authors: Briggs David
Published: March 2021

At the time of writing, nation states globally are beginning the vaccination process in response to Covid-19. There is great expectation that it will deliver effective protection to most populations. The logistic of the production and delivery of the vaccines, and use are immense and, we are fortunate, in the Australian context that the extent of the virus spread, and impact has been relatively limited and mostly contained. While everyone is wanting rapid progress, our context does allow us the opportunity to ‘hasten slowly’ and have a positive outcome....
ЗНАЧУЩІСТЬ ХУДОЖНЬО-ТВОРЧОГО РЕСУРСУ У ПРОФЕСІЙНОМУ СТАНОВЛЕННІ ВОКАЛІСТА: МИСТЕЦЬКО-ІСТОРИЧНИЙ ПОГЛЯД
Authors:   Сумський державний педагогічний університет імені А. С. Макаренка, Крамська Світлана , Руденко Олександр
Published: March 2021

У статті розкривається сутність поняття «художньо-творчий ресурс», висвітлюються історичні аспекти виникнення даного феномену як особливого явища в мистецтві. Робота розкриває природу досліджуваного феномену й висвітлює основні мистецькі площини, у ракурсі яких слід розглядати його зміст і сутність: у художньо-творчій, що розкриває внутрішній духовний світ вокаліста, його почуття, уявлення та систему цінностей; у технічно-виконавській, пов’язаній безпосередньо і вокальним апаратом вокаліста-виконавця і його виконавськими можливостями. Розглянуто головні дієво-творчі позиції художньо-творчого ресурсу, визначено його важливість у контексті підготовки майбутнього вокаліста і його подальшого професійного становлення, окреслено значимість та унікальність досліджуваного феномену у практиці сучасної вокальної школи.
Pemberdayaan Masyarakat Kelurahan Trimulyo Semarang Melalui Program Gerbang Hebat
Authors: Kristiyanti Mariana
Published: March 2021

The city of Semarang is currently improving to actualize the saying of 'Moving Together Building the City of Semarang to Be Better and Great' both physically and non-physically. One of them is through Gerbang Hebat program. It is an activity in reducing poverty and unemployment, improving public services, gender equality and improving education also health as stated in the Sapta program (Reducing poverty and unemployment, Handling Floods, Improving Infrastructures, Improving Public Services and Gender Equality). UNIMAR AMNI Semarang carried out community service activities at Trimulyo village to support the government of Semarang program. It is not only students/cadets and lecturers who carry out community service activities but also the surrounding community. They are very enthusiastic in participating in implementing various program activities carried out at  Trimulyo village. The activity begins with planting mangrove trees, socializing healthy living in an unhealthy environment, training in cooking and tidying up the environment.The method of implementing the activities used is the method of observation, interviews and literature studies. The observation was held in Trimulyo village, sub-district of Genuk. The data collection was carried out through interview methods and as a reference for implementing community service activities was using the literature study method. With UNIMAR AMNI Semarang Gerbang Hebat program at Trimulyo village of Subdistrict Genuk hoped that it can improve the healthy lifestyles and increase the income of the Trimulyo village community.
Peningkatan Kesejahteraan Anggota Unit Simpan Pinjam ADELWIS Berbasis Maqoshid Syariah
Authors: Khajar Ibnu , Nurcholis Lutfi , Cahyono Budhi , Nugroho Marno
Published: March 2021

Tujuan pengabmas ini adalah merubah pola pikir dari anggota unit simpan pinjam ALDEWIS dari pola konsuntif menjadi berorientasi tujuan produktif dengan tolok ukur yang bisa digunakan adalah berapa banyak dari jumlah anggota ALDEWIS yang mempunyai unit usaha informal sebelum dan sesudah kegiatan abdimas dilaksanakan, membangun jejaring dengan instansi terkait seperti lembaga-lembaga social (Lembaga zakat, dll) untuk menambah kapasitas jumlah dana yang disalurkan baik secara kuantitas maupun kualitas, memotivasi para anggota ALDEWIS untuk hidup sederhana dan gemar menabung dan memotivasi para anggota ALDEWIS untuk melakukan usaha dengan keputusan yang terinformasikan, dalam arti sudah mempertimbangakan informasi keuangan yang relefan serta aspek-aspek maqosid syariah.Pengabmas ini dilakukan dengan kegiatan dengan konsep berbasis diskusi interaktif untuk semua anggota unit simpan pinjam ALDEWIS, dengan fokus utama untuk memotivasi para anggota ALDEWIS, untuk pemanfaatan dana pinjaman berorientasi produktif dan tidak semata-mata konsumtif. Kegiatan dilakukan dengan konsep berbasis kelompok, dengan satu kelompok terdiri dari 5 orang Ibu RT dengan fokus utama pada kegiatan produksi dan marketing produk jajanan pensupply warung angkringan di wilayah perumahan Pucanggading. Pengabmas ini menggunakan pendekatan yang komprehensif, karena melibatkan kelompok Ibu RT anggota unit simpan pinjam ALDEWIS, tim FE Unissula, LPPM Unissula.
A Social Media Analytics Framework to Increase Prospective Students’ Interests in STEM and TVET Education
Authors: Muhamad Adnan Muhamad Hariz , Ariffin Shamsul Arrieya , Hanafi Hafizul Fahri , Husain Mohd Shahid , Panessai Ismail Yusuf
Published: March 2021

Recently, the promotion of Science, technology, engineering and mathematics (STEM) education has become the highlight due to the shortage in the STEM workforce. Surprisingly, the enrolment rates in STEM degrees are still low in many countries. Social media has been identified as one of the main platforms that can help to increase prospective students’ interest in STEM and also Technical and Vocational Education and Training (TVET) subjects. However, very little research has been done for the higher education institutions in Malaysia in leveraging social media and social media analytics effectively to increase the students’ interests and awareness of STEM and TVET disciplines. Therefore, this paper aims to propose a framework to increase prospective students’ interest in STEM and TVET using social media and big data analytics. The objectives of this study are to explore various social media applications in education and study these applications towards increasing students’ interests and propose a suitable framework for Malaysian higher education institutions. The framework is proposed by following the theory synthesis methodology. Four main components of the framework have been proposed, namely social media, role model or mentoring, massive open online courses and big data analytics. Each component is significant and requires a considerable amount of time to develop. The suggested framework is anticipated to benefit higher education institutions with a significant gain of the number of students, revenues and positive reputations.

 

Keywords: Social media, Social media analytics, STEM, E-learning, Education
Development of Augmented Reality (AR) for Innovative Teaching and Learning in Engineering Education
Authors: Md Enzai Nur Idawati , Ahmad Norhayati , Ab. Ghani Mohd Amir Hamzah , Rais Siti Sara , Mohamed Syazilawati
Published: March 2021

Engineering education in particular involves laboratory equipment and apparatus which requires safety procedures and substantial financial cost. Recent pandemic has also affected engineering education teaching and learning processes as all the classes and laboratory sessions need to be conducted via online distance learning (ODL) method. Therefore, this research selects Augmented Reality (AR) Method for innovative teaching and learning process. AR is known for its ability to overlay rich media into the real world by viewing through web-enabled devices such as phones and tablets, making it accessible anywhere anytime. In addition to improving interest and motivation of students during the learning process, AR could also address the financial and space constraints pertaining to science and technology laboratory equipment and apparatus. In this research, an AR has been developed according to system development method by using Assemblr application. The developed AR system is then given to selected educators to be evaluated in terms of their awareness and the system’s usability. The educators’ responses are obtained through a questionnaire survey and the findings are then analysed and presented in this paper. The responses are taken into account for improving the AR system and the development process will be continued in parallel with more testing. The final prototype will then be implemented in real classes in the future.

 

Keywords: Augmented Reality, Education, Engineering