bluuebunny/crossref_metadata_2025 huggingface dataset:
Neuro physiotherapy in Chemotherapy Induced Peripheral Neuropathy -- a Case Report
Authors: Seth Nikita H. , Qureshi Moh’d Irshad , Raghuveer Raghumahanti
Published: November 2023

Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent,
debilitating, potentially severe, and frequently dose-limiting adverse
reaction to several first- and second-line chemotherapy drugs with
limited access to efficient, satisfactory treatment. Proprioceptive
Neuromuscular Facilitation technique was found significant in reducing
peripheral neuropathy symptoms and improves quality of life, despite
differences in the processes of damage. Here, we describe the
application of Proprioceptive neuromuscular facilitation techniques in a
56-year-old female patient suffering from Stage II uterine cancer
admitted to the Chemotherapy ward for a second cycle of chemotherapy and
were referred for Neurophysiotherapy in order manage
chemotherapy-induced peripheral neuropathy symptoms. The patient had
complaints of pain along with weakness in the lower limbs and tingling
in both the feet along with difficulty in maintaining balance while
walking. So Physiotherapy rehabilitation was initiated after 3 days of
beginning of anti cancer medications. After the four-weeks of
physiotherapy sessions, the patient reported total remission of pain, a
significant decrease in tingling and numbness in both lower extremities.
CIPN can and often does persist for many years, even though it usually
resolves gradually over time. It seems improbable that this was a
spontaneous resolution given the consistency of his symptoms before
starting physiotherapy sessions and their quick improvement with
treatment. Further Research is required to ascertain if improvements in
CIPN symptoms are directly or indirectly associated with increase in
blood flow, as well as to comprehend the role of physiotherapy, a
nontoxic, non pharmacologic intervention, in CIPN amelioration.
A sustainable strategy for biosynthesis of Rebaudioside D using a novel glycosyltransferase of Solanum tuberosum
Authors: Ma Siyuan , Ma Yuanyuan
Published: November 2023

Bioconversion of Rebaudioside D faces high-cost obstacles. Herein, a
novel glycosyltransferase StUGT converting Rebaudioside A to
Rebaudioside D was screened and characterized, which exhibits stronger
affinity and substrate specificity for Rebaudioside A than previously
reported enzymes. A whole-cell catalytic system was thus developed using
the StUGT strain. The production of Rebaudioside D was enhanced
significantly by enhancing cell permeability, and the highest production
of 6.12 g/L (yield=98.08%) by cell catalyst was obtained by
statistical-based optimization. A new cascade process utilizing this
recombinant strain and E. coli expressing sucrose synthase was further
established to reduce cost through replacing expensive UDPG with
sucrose. A StUGT-GsSUS1 system exhibited high catalytic capability, and
5.27 g/L Rebaudioside D was achieved finally without UDPG addition by
systematic optimization. This is the best performance reported in
cell-cascaded biosynthesis, which paves a new cost-effective strategy
for sustainable synthesis of scarce premium sweeteners from biomass.
A Siddha Management of Attai vidal (Leech therapy) with internal and external medicines for Naalavibatha Punn (Varicose Ulcer): A Case Report
Authors: C.B.S. Bharath , P Nirmala , S Ethel , J Jayalakshmi
Published: November 2023

According to various classical Siddha literature, the varicose ulcer is
compared with the symptoms of Naalavibatha punn / Naalasurrutu punn /
Naalaviruvu punn. Treat varicose ulcers by prescribing Siddha internal
medicines and external therapies. On August 5, 2022, a 48-year-old
female patient attended the OPD of Santhigiri Siddha Medical College and
Hospital, Trivandrum, with the following complaints: dilatation of veins
present in the right lower limb for 6 years; hyperpigmented lesion with
itching and swelling above the medial malleolus of the right lower limb
for 6 months; and an ulcer present above the medial malleolus for the
last 3 months. She had a known case of varicose veins and had taken
sclerotherapy three times but did not have satisfaction with the
allopathic medication. The majority of the symptoms were significantly
reduced in 60 days under the Siddha medications, such as a combination
of Siddha preparation (Parangipattai Chooranam, Sangu Parpam, and
Silasathu Parpam), Rasa gandhi mezhugu for internal, Padikara neer
washing, wound dressing with Mathan thailam for external for 2 months,
and attai vidal (leech application) done in 3 sittings in the gap of 10
days. No recurrence of any chronic varicose ulcer was observed during
the 1 year of follow-up, and relevant preventive Siddha medication for
Naalavibatha punn was given and advised the patient to do exercises that
strengthen the legs and compression therapy. To summarize, the case
report exhibited that Siddha leech therapy with both internal and
external medications is very effective in the management of varicose
ulcers.
Climate Change, the Floor Heating Effect Caused by Fossil Energy Mining
Authors: Mu Xinzhi , Mu Yao
Published: November 2023

In this paper, it is discussed that the oil-gas wells of mining
construction penetrates the cap rock of geothermal reservoirs system and
massive loss of geothermal energy lead to the floor heating effect in
fossil energy mining processes, and its importance to global climate
change. It is also illustrated the interrelationship among fossil energy
mining, deep ground temperature rises as well as deep sea warming. Thus,
it expresses significance by energy mining affecting environmental
ecosystem and climate change in globe.
The Value of Auditor Verification Amid Economic Uncertainty: International Evidence from Small Businesses
Authors: Ai Xi , Lin Chenxi , Newton Nathan J.
Published: November 2023

We examine the value of auditor verification to small businesses when they face economic uncertainty. The COVID-19 pandemic was a significant, exogenous economic shock that immediately heightened the need for external funding for many companies. Using a sample of small, private companies from 21 countries, we examine how the receipt of an audit prior to the pandemic affects the primary type of financing companies obtain during the pandemic. We find that companies with audited financial statements available are more inclined to secure primary funding from bank loans rather than from equity contributions from existing owners or new investors. However, an audit is not associated with primary funding from government sources. We also document that businesses benefit most from an audit when information asymmetry and economic disruption are relatively high and when the supply of government liquidity support is relatively low.

Data Availability: Data are available from the public sources cited in the text.

JEL Classifications: M21; M42.
Drug Survival and Long-term Outcome of Tofacitinib in Patients with Alopecia Areata: A Retrospective Study
Authors: Huang Jundong , Deng Sihan , Li Ji , Tang Yan , Liu Fangfen , Liu Yu , Rao Shijia , Shi Wei
Published: November 2023

Several non-randomized clinical trials and retrospective studies have demonstrated encouraging efficacy and well-tolerated safety of tofacitinib in the treatment of alopecia areata. However, there are scarce data on a large cohort of patients with alopecia areata in long-term real-world practice. This single-centre, retrospective, observational cohort study included 126 patients with alopecia areata treated with tofacitinib between February 2021 and December 2022. The aims of this study are to evaluate drug survival, effectiveness and safety of tofacitinib for treatment of alopecia areata, and to identify potential factors influencing long-term outcomes. Median duration of treatment was 23.00 (interquartile range (IQR) 15.00, 47.25) weeks. Median all-cause survival time of 126 patients treated with tofacitinib was 44 weeks (95% confidence interval (95% CI) 36.3, 51.7), and the all-cause drug retention rate at 12 weeks, 24 weeks and 48 weeks were 90.0%, 66.4% and 42.3%, respectively. The most common reason for discontinuation was complete remission/satisfaction. A total of 80 patients treated with tofacitinib for over 6 months were included in the efficacy analysis, the overall complete response rate at 24 weeks was 33.8% (27/80). No life-threatening serious adverse events occurred. Sex is an independent risk factor in predicting patient outcomes. This real-world study confirmed the high effectiveness and acceptable safety profile of tofacitinib in alopecia areata, with a satisfactory drug survival rate, and provides supporting data for the clinical application of tofacitinib in Chinese patients with alopecia areata.
Exploring structural brain changes in children with neonatal brachial plexus palsy: a voxel-based morphometry analysis
Authors: Kadieva Dzerassa  V. , Gallo Federico , Ulanov Maxim  A. , Shestakova Anna  N. , Moiseeva Victoria  V. , Hodorovskaya Alina  M. , Agronovich Olga  E.
Published: November 2023

BACKGROUND: Obstetric brachial plexus palsy (OBPP) is paralysis of the upper limb resulting from nerve injury during vaginal delivery. Although current treatment approaches frequently lead to complete reinnervation of the limb, some patients show long-term motor deficits. These impairments may result from upper limb disuse that causes structural brain changes.
AIM: This study aimed to compare deep gray matter volumes between children with OBPP and healthy controls.
METHODS: We analyzed the structural magnetic resonance imaging results of 46 children with OBPP (n=24, mean age — 10.20, of whom 12 were girls) and healthy age-matched controls (n=22, mean age — 9.63, of whom 10 were girls) using a voxel-based morphometry technique in SPM12 package (Statistical Parametric Mapping) in MATLAB R2019b. To minimize false discoveries, we used a stringent procedure to control the family-wise error rate.
RESULTS: We found volumetric brain differences between children with OBPP and healthy controls (all FWE-corrected p 0.005). Children with OBPP had significantly lower gray matter volumes in the left amygdala, bilateral hippocampus, and right entorhinal cortex.
CONCLUSION: Integrating our findings with previous work, we speculate that the amygdala–hippocampus–entorhinal cortex complex might play a significant role in motor disorders.
Modeling and control of an electromechanical system with a permanent magnet generator and a voltage source converter
Authors:   Institute of Electrodynamics of the National Academy of Sciences of Ukraine, Mazurenko Leonid , Grebenikov Viktor , Dzhura Oleksandr ,   Institute of Electrodynamics of the National Academy of Sciences of Ukraine,   Institute of Electrodynamics of the National Academy of Sciences of Ukraine, Shykhnenko Maksym
Published: November 2023

In the paper simulation dynamic models for the analysis of characteristics and transients of electromechanical system using a permanent magnet electric generator (PMG) connected to a variable speed fixed pitch wind turbine (WT) and a voltage source converter (VSC) mathematical models are developed. The system supplies a direct current (dc) resistive load through a controlled switch. The objective of the controlled resistive load connected to the VSC dc circuit of the system is to perform the dc output voltage stabilization for simulating the mode of generating the active power into a grid via a grid invertor. Two algorithm structures of realization of tracking the optimal WT motion trajectory in the coordinates “WT aerodynamical power – rotary speed” have been considered. The tracking algorithms function is to provide the maximization of power extraction from wind flow by WT. Electromechanical processes in the PMG – VSC system for both tracking algorithms have been investigated using developed dynamic simulation models and vector control technique of electromagnetic torque of the generator at variable WT mechanical power. The results of numerical investigations of the electromagnetic processes in the system have been analized. The efficiencies of the proposed control algorithms applied to the VSC in the considered electromechanical system have been compared and discussed.
O TRABALHO COMO PRINCÍPIO EDUCATIVO: um estudo na Revista Brasileira de Educação Profissional e Tecnológica
Authors: Oliveira dos Santos Siqueira Adriana , Machado Ferreira Luis Claudio , Nunes da Silva José Moisés
Published: November 2023

O artigo objetiva analisar a concepção de trabalho como princípio educativo, abordada nas publicações da Revista Brasileira de Educação Profissional e Tecnológica. A metodologia, de abordagem qualitativa, está ancorada no estado do conhecimento por meio de revisão de literatura, compreendida no período de 2008 a 2022. Os resultados, analisados à luz da Análise Textual Discursiva e com o aporte de autores como Marx (1996, 2013), Gramsci (2001), Manacorda, (2007), Saviani (2007, 2013), Kuenzer (1989, 2020) e Moura, Lima Filho e Silva (2015), entre outros, mostram que há compreensão do conceito de trabalho como princípio educativo em alguns artigos; e pouca clareza conceitual em parte significativa das publicações, que apenas citam o termo sem problematizá-lo e estabelecer relações com o objeto de suas investigações, demonstrando a necessidade de aprofundamento de estudos e reflexões sobre a base material na qual se realiza a construção social do trabalho como princípio educativo, particularmente, no campo da educação profissional e tecnológica.
Particle swarm methods for transport and logistics optimization processes
Authors: Lisowski Józef
Published: November 2023

This article describes heuristic approaches to static optimization methods, taking into account the nature of the motion of a swarm of particles representing, for example, birds, ants, bees, fireflies, bats, krill, cuckoos, cuttlefish, cockroaches, or the pollination process of flowers. In the given descriptions of the methods, the features of swarm intelligence are detailed, the optimization quality indicators are formulated, and flow charts of the computational algorithms are provided.
Presentación del dosier: Prácticas pedagógicas y estrategias didácticas en la enseñanza de las ciencias de la información: nuevos saberes y abordajes
Authors: Corda María Cecilia , Coria Marcela
Published: November 2023

Presentación del dosier: Prácticas pedagógicas y estrategias didácticas en la enseñanza de las ciencias de la información: nuevos saberes y abordajes
Por qué el fundacionismo no funciona: una respuesta a Miguel Ángel Rendón Rojas
Authors: Saraiva Ignacio , Melogno Pablo
Published: November 2023

Recientemente, Rendón Rojas ha defendido la idea de que las disciplinas, y en particular la ciencia de la información, necesitan algún tipo de fundamento para su funcionamiento. A su vez, en su ataque al antifundacionismo remite a que este no es posible ya que es inviable evadir el principio de razón suficiente, y que adopción conlleva al relativismo y subjetivismo. Por lo que, el objetivo del presente trabajo es desarrollar una discusión crítica de la propuesta de Rendón Rojas, desde una perspectiva antifundacionista. Para ello, se realiza una revisión de literatura y se analizan las diversas variantes del fundacionismo como corriente filosófica, en orden de poder establecer las principales críticas que se le han realizado. Se presentan los argumentos de Sellars a la hora de considerar al fundacionismo y al mito de lo dado. Se examinan las críticas de relatividad y subjetividad realizadas al antifundacionismo. Se realiza una discusión crítica sobre el principio de razón suficiente como bastión para las disciplinas, se sustenta que su presentación es un área de controversia y debate. Se presenta una visión antifundacionista para la ciencia de la información. Se concluye que el antifundacionismo ofrece un campo fértil a la hora de pensar cómo se consolidan las disciplinas científicas, cómo logran los consensos y acuerdos comunitarios.
Competência cultural na gestão da diversidade: estudo de caso em uma biblioteca pública
Authors: Silva Bruna Daniele de Oliveira , Camillo Everton da Silva , Guaraldo Tamara de Souza Brandão
Published: November 2023

O artigo tem como referencial teórico a gestão da diversidade e a competência cultural. Tem como objetivo identificar os modos de gestão da diversidade em uma biblioteca pública do interior do estado de São Paulo, estabelecendo uma reflexão teórica entre essa gestão e o desenvolvimento da competência cultural na organização. Foram avaliadas as relações entre os propósitos do planejamento organizacional e as ações desenvolvidas pela equipe da biblioteca. Foi identificada a importância da informação e da comunicação para a promoção da diversidade e avaliada a percepção de conflitos na biblioteca. A diversidade cultural e a competência cultural foram consideradas nos processos organizacionais. Aplicou-se o método de pesquisa Estudo de Caso. Os resultados consistem no seguinte: a biblioteca possui uma abordagem de gestão alinhada com o objetivo de ser uma referência cultural local para as diversas culturas, experiências e subjetividades; a própria equipe da biblioteca indica a percepção da diversidade da biblioteca e a importância da representatividade para o desenvolvimento e execução de projetos interculturais; a informação e a comunicação entre a biblioteca e o público auxiliam no compromisso com a diversidade; a biblioteca tem como objetivo promover atividades que ajudem diferentes grupos sociais. A pesquisa conclui que o desenvolvimento de competências nos níveis individual e organizacional é uma solução para atingir a convivência e a integração de grupos multiculturais. Desta forma, a competência cultural demanda ações que envolvem fluxos de informação e comunicação eficientes entre grupos de indivíduos distintos; isso pode potencializar a gestão da diversidade nas organizações.
Ana María Martínez Tamayo, in memoriam
Authors: Mendes Paola Verónica , Corda María Cecilia
Published: November 2023

Ana María Martínez Tamayo, In memoriam
Jakie informacje zawiera charakterystyka produktu leczniczego i jaka jest jej rola?
Authors: Mirowska-Guzel Dagmara
Published: November 2023

Charakterystyka produktu leczniczego jest obowiązkowym dokumentem koniecznym do rejestracji produktu leczniczego (leku), czyli dopuszczenia go do obrotu. Leki w Polsce są rejestrowane w ramach procedur obowiązujących w systemie europejskim, a szczegółowo wskazanych przez Europejską Agencję Leków. W artykule przedstawiono procedury rejestracyjne, zawartość charakterystyki produktu leczniczego, źródła, w których można znaleźć ich aktualne wersje i ich znaczenie dla lekarza praktyka, ze szczególnym uwzględnieniem programu lekowego (B.29) leczenia stwardnienia rozsianego.
Terapia ofatumumabem – optymalizacja leczenia chorych z rzutowo-remisyjną postacią stwardnienia rozsianego
Authors: Puz Przemysław
Published: November 2023

Optymalizacja terapii u pacjentów z rzutowo-remisyjną postacią stwardnienia rozsianego leczonych już wcześniej wymaga indywidualnego podejścia w przypadku każdego chorego. Ofatumumab jest lekiem stosowanym u chorych z rzutowo-remisyjną postacią stwardnienia rozsianego, mającym wysoką skuteczność, a jednocześnie korzystny profil bezpieczeństwa. W pracy przedstawiono opisy dwóch pacjentek, u których konieczna była zmiana terapii modyfikującej przebieg choroby. U pierwszej pacjentki w trakcie terapii stwierdzono częściową nieskuteczność początkowo zastosowanego leku I linii. Zdecydowano o zamianie leczenia na ofatumumab jako lek o wysokiej skuteczności dostępny w I linii leczenia stwardnienia rozsianego programu lekowego Ministerstwa Zdrowia. U drugiej chorej ofatumumab zastosowano jako kolejną terapię w związku z występowaniem aktywności choroby i działań niepożądanych w trakcie stosowania wcześniejszych leków modyfikujących przebieg choroby.
Artefacto social nº 00. Nos falta calle nº 1488
Authors: Rivas Herencia Eugenio
Published: November 2023

Artefacto Social es un plan de formación perteneciente al programa Key-Project del Vicerrectorado de Innovacio´n Social y Emprendimiento de la Universidad de Málaga. La propuesta nace desde la Facultad de Bellas Artes de esta Universidad con el propósito de implementar, a trav´s del arte, competencias intrínsecas de la creación colectiva como herramienta de impacto social. Asimismo, se pone en marcha con la intención de fomentar entre los estudiantes de la Universidad de Málaga el empleo de la práctica artística grupal como el factor de cambio, eje de mediación y empoderamiento social. De este modo, de ende que mediante la puesta en práctica de un arte de relaciones puede alimentarse el vínculo del individuo con el territorio al que pertenece y reforzar el sentimiento de comunidad.
Oral argumentation and language-aware civic education – a theoretical proposal
Authors: Sobernheim Janine
Published: November 2023

Oral argumentative competence is highly relevant for responsible [mündige] participation in social negotiation processes. Thus, promoting argumentative competence is central to civic education. However, there is a lack of theoretical concepts and empirical findings which can guide action in the civic education classroom. Since argumentative competence is a linguistic skill, the concept of language-aware civic education offers itself as a plausible framework. In this article, the two terms oral argumentative competence and language-aware subject teaching are clarified within the context of civic education. It is shown how subject-specific oral argumentative competence can be fostered through language-aware civic education.
Thermal welding frenotomy on neglected tongue tie: a case report
Authors: Fakhriani Rizka , Amsriza Fadli Robby
Published: November 2023

Introduction: Tongue tie, also known as ankyloglossia, is characterized by a small lingualfrenum that often prevents the tongue from moving. It is a rare congenital mouthabnormality that might lead to functional problems such as improper swallowing, speechdifficulty, and psychological stress. This study's purpose of providing an unusual incidenceof neglected tongue tie with thermal welding frenotomy.Case Presentation: A 4 years old male patient was bought by his parent to the Departmentof Otorhinolaryngology-Head and Neck Surgery with the chief complaint of offensivespeech. The patient cannot speak the word F, R, T, L, D. Additionally, the parent said that hewas unable to chew solid meals. There was a history when the patient was a baby; hismother could not breastfeed him. According to the clinical examination, the patient had atongue tie with a thick frenum, limited tongue movements like protrusion, and elevation ofthe tongue tip. A bifid or heart-shaped structure was seen on the front tongue tip.Discussion: The patient underwent a thermal welding frenotomy under intravenoussedation. This approach's effectiveness relies on using heat and pressure to block bloodarteries. This study established the novel technology as a secure procedure for tongue tie.After a frenotomy procedure, patients show an improved ability to articulate consonantsbetter.Conclusion: This study supports thermal welding frenotomy as an efficient and securetreatment for children with tongue tie.
Secondary syphilis in a 13-year-old Indonesian girl: a social problem
Authors: Achdiat Pati Aji
Published: November 2023

Introduction: Secondary syphilis is characterized by skin and mucous eruptions, such as condyloma lata. Syphilis cases are rare in children. Several factors could influence sexually transmitted infections (STIs) in children, such as lack of knowledge of STIs, parenting, social environment, parents’ marital status, occupation, and education. We reported one social case of secondary syphilis in a 13-year-old girl. Case Presentation: We did history taking, physical, and laboratory examinations. From history taking, the patient did not know about the signs and symptoms of STIs, has bad parenting, a bad social environment, divorced parents, and parents’ low education. On physical examination, there were skin-colored papules, plaques, and nodules on the labia majora, minora, and perianal. The venereal disease research laboratory (VDRL) result was reactive. The patient was treated with single dose injection of 2.4 million international units benzathine penicillin G and was educated for signs, symptoms, and complications of STIs, and the danger of risky sexual behavior. There were improvement of the lesions 10 days after therapy, decreased of VDRL titer 4x in one month after therapy, and no longer have sexual activity. Conclusion: Social condition can cause STIs in children. The bigger scope of education programs for children is needed to prevent STIs.
Spontaneous improvement of lateral spondylolisthesis on scoliosis after correction of scoliosis deformity
Authors: Saddalqous Saddalqous
Published: November 2023

Introduction: By definition, scoliosis is a three-dimensional deformity of the spine. From the etiologic, scoliosis can be divided into three kinds, congenital scoliosis, neuromuscular scoliosis, and the most common type, idiopathic scoliosis. Several patients experience spondylolisthesis concomitant with scoliosis. Understanding the pathoanatomic of these two abnormalities is very important to achieve optimal treatment. The problem lies in the extent to which vertebral instrumentation is necessary.Case presentation: The authors describe five idiopathic scoliosis patients with spondylolisthesis. We also used the Lenke classification to categorize these patients. The patient came with the complaint of a crooked back. All patients did not complain of back pain. The patients were diagnosed with idiopathic scoliosis from the physical and radiological examination. Concomitant spondylolisthesis was found in all five patients. The surgeon decided to perform deformity correction surgery followed by posterior stabilization fusion for scoliosis. There is no specific corrective surgery for the patients' spondylolisthesis.Discussion and Conclusion: Scoliosis has its challenges for orthopedic spine surgeons. Many things must be assessed in scoliosis, such as history, physical examination, full spine x-ray evaluation, Lenke classification, and instrumentation measures. Spondylolisthesis associated with scoliosis generally occurs in the lower lumbar segment. The pathoanatomic of spondylolisthesis concomitant with scoliosis was divided into two kinds and can be grouped according to three theories. Each of these theories will lead to appropriate treatment actions. Deformity correction is aimed at one pathoanatomic but improves both abnormalities if the appropriate treatment is taken.
The influence of cocoa fruit husk extract on the degradation of eps (extracellular polymeric substance) in Lactobacillus acidophilus biofilm
Authors: Regita Azimah
Published: November 2023

Introduction: Dental caries is characterized by progressive demineralization and plaque formation by Lactobacillus acidophilus bacteria due to biofilm formation as a microbial defense mechanism that binds to EPS. To address this issue, cocoa fruit husks extract is utilized as it contains active flavonoids with antibacterial properties. Objective: Demonstrate that cocoa fruit husk extract can degrade Lactobacillus acidophilus bacterial EPS biofilm and determine the optimal concentration of cocoa fruit husk extract. Methods: Cocoa Fruit Husk Extract Preparation was followed by Lactobacillus acidophilus bacterial preparation. Dilution was performed to achieve a concentration of 106 Bacteria/mL. Microtiter plates with flat-bottom 24 wells were sealed. They were then divided into two groups: one as a control without cocoa fruit husk extract and the other with cocoa fruit husk extract at concentrations of 1.56%; 3.125%; 4.69%; 6.25%; and 7.8%, and incubated at 35°C for 24 hours. Subsequently, they were aspirated, washed 4 times with phosphate-buffered saline, stained with dextran alexa fluor 647, and rinsed with distilled water. Biofilm sections, 0.5 mm thick, were placed on glass slides, and EPS Biofilm was measured using CLSM at 40x magnification. Results: The division into microtiter plates showed that the 7.8% concentration had the highest potential with a value of X ± SD = 8.3366 ± 1.76364 in degrading EPS biofilm compared to others. This is in line with previous research, indicating that higher extract concentrations lead to better biofilm degradation activity. Conclusion: Cocoa fruit husk extract can degrade Lactobacillus acidophilus bacterial EPS biofilm, with the most optimal concentration being 7.8%.
THE EFFECTS OF TEACHER'S MOTIVATIONAL STRATEGIES ON EFL LEARNER'S SPEAKING ABILITY IN JUNIOR HIGH SCHOOL
Authors: Margareta Widya Lutfi , Savitri Wiwiet Eva
Published: November 2023

Learners utilize their speaking ability to communicate, elicit an idea or point of view, convey their ideas and desires, and socialize oneself in order to interact with others. The ability to talk is used to evaluate English comprehension. On the other hand, many EFL learners' ability to use English for oral communication is still low, due to fear and shy. Therefore, EFL learners need motivation to strengthen their confidence. There is one method to achieve it that is teacher's motivational strategies. Thus, this study aims to determine the effect of teacher's motivational strategies on EFL learner's speaking ability. In achieving this goal, the researcher used mixed method research. For the quantitative phase, experimental study was utilized to assess the effect between variables X, the teacher's motivational strategies as an independent variable, and Y, the learner's speaking ability as a dependent variable. Meanwhile, the field notes observation is used in qualitative phase. The post-test of both the experimental and control groups is .029 which is smaller than .05. It is acceptable to assume that there is a significant difference between the experimental and control groups. The calculation shows that the teacher's motivational strategies increase the learner's speaking ability. From the field notes observation, it wshowed that they can participate actively in classroom when teachers are applying motivational strategies or treatment. It can conclude that teachers' motivational strategies increase learner's speaking ability in experimental group.
TEACHERS' QUESTIONS TO PROMOTE STUDENTS' CRITICAL THINKING IN EFL CLASS
Authors: Noni Agustina  , Al Baqoroh Rini
Published: November 2023

Critical thinking has important role in the EFL class. It can be developed through questioning. However, English teachers are rare to address the critical thinking questions to their students. Therefore, this study aims to investigate to what extent teachers use questions to promote students' critical thinking. This study employed a qualitative approach with open-ended questionnaires and interview to collect data. Seventy-eight of English junior high school teachers in Indonesia were involved in this study. The results of this research revealed that majority teachers employed critical thinking questions. They posed the questions for clarification, assumption, reasons and evidence, viewpoints or perspective, the implication, consequence or alternative, prediction, agreement and disagreement, and summary and conclusion to promote students' critical thinking skill.
THE FACTORS THAT INFLUENCE STUDENTS' INTEREST TO CHOOSE THE HOSPITALITY MAJORS
Authors: Adiwijaya Pande Agus , Yasmin Putri , Wedayanthi Wedayanthi , Hasibin Nur , Purwantara I Komang Gde Trisna
Published: November 2023

This study aims to determine the factors that influence students' interest in choosing Hospitality Majors at SMK N 1 Susut. The study used a convergent parallel design of mixed-method research. The qualitative data were collected through interviews and observation while the quantitative data were collected through a survey with 30 students of respondents. The results of the study showed that factors that come from internal and external students influence students' interest in choosing hospitality majors at SMK N 1 Susut. The internal factors of the students choosing Hospitality Majors are (1) students'' talent, and (2) students' interest in the hospitality industry. In terms of external factors, these students were affected by (1) parents' encouragement, (2) the living environment, (3) the potential and opportunities for future work, and (4) the school program.
KONFLIK KEPRIBADIAN NEUROTIK PADA TOKOH UTAMA DALAM NOVEL DAKSA KARYA RIZKI ANJARANI
Authors: Pratiwi Hermalinda Rizki , Dewi Trie Utari
Published: November 2023

ABSTRAK: Tujuan dari penelitian ini adalah untuk mendeskripsikan wujud konflik kepribadian neurotik dan upaya yang dilakukan dalam mengatasi konflik kepribadian neurotik yang dialami oleh tokoh utama. Penelitian ini menggunakan metode penelitian kualitatif. Data dari penelitian ini adalah teks, kalimat, dan dialog yang berkaitan dengan konflik kepribadian dan upaya pengatasannya. Sumber data pada penelitian ini adalah novel Daksa karya Rizki Anjarani. Teknik pengumpulan data pada penelitian ini adalah teknik simak dan catat. Teknik analisis data yang digunakan yaitu teknik analisis isi dengan cara menandai dan mengelompokkan teks, kalimat, dan dialog yang terkait dengan konflik kepribadian dan upaya pengatasan konflik kepribadian berdasarkan teori Karen Horney. Konflik kepribadian yang ditemukan pada penelitian ini terbagi menjadi 2 bentuk konflik yaitu, konflik interpersonal dan konflik intrapsikis. Upaya dalam mengatasi konflik kepribadian yang terjadi dilakukan dengan tiga acara yaitu, bergerak mendekati orang lain, bergerak melawan orang lain, dan bergerak menjauhi orang lain. Ketiga cara tersebut dilakukan oleh tokoh utama pada novel Daksa agar konflik yang terjadi dalam diri tokoh utama dapat diredakan dan diatasi.KATA KUNCI: Konflik Kepribadian; Neurotik; Novel; Psikoanalisis.THE MAIN CHARACTER PERSONALITY CONFLICT IN THE NOVEL DAKSA BY RIZKI ANJARANI: A REVIEW OF KAREN HORNEY'S SOCIAL PSYCHOANALYSIS. ABSTRACT: The purpose of this research is to describe the form of neurotic personality conflict and the efforts made to overcome the neurotic personality conflict experienced by the main character. This study used qualitative research methods. The data from this study are texts, sentences, and dialogues related to personality conflicts and efforts to overcome them. The source of the data in this study is the novel Daksa by Rizki Anjarani. The data collection technique in this study is the observing and noting technique. The data analysis technique used is content analysis technique by tagging and grouping texts, sentences, and dialogues related to personality conflicts and efforts to overcome personality conflicts based on Karen Horney's theory. The personality conflicts found in this study are divided into 2 forms of conflict, namely, interpersonal conflict and intrapsychic conflict. Efforts to overcome personality conflicts that occur are carried out in three ways, namely, moving towards other people, moving against other people, and moving away from other people. These three methods are carried out by the main character in Daksa's novel so that the conflict that occurs within the main character can be mitigated and overcome.KEYWORDS: Personality Conflicts; Neurotics; Novels; Psychoanalysis.
PENERAPAN METODE MATRIX TRANSPORTASI BOWMAN UNTUK MEMINIMUMKAN BIAYA PADA PERENCANAAN PRODUKSI
Authors: Paudi Rivka , Nurwan Nurwan , Payu Muhammad Rezky Friesta
Published: November 2023

Istana Coklat Bakery, one of the bread industries in Gorontalo, produces two types of products, namely birthday cake and cake. Production planning in the istana Coklat Bakery begins with forecasting demand using double moving average method to production cost data, and production costs as variables that will be counted in the Bowman Transportation Matrix. based on the research results, obtained that the production process was fulfilled for regular production and overtime production using the Bowman Transportation Matrix method.  The total cost obtained from production planning using the Bowman transportation matriks method is IDR 864,437,500.
EFEKTIVITAS MODEL PEMBELAJARAN SIMULASI BERBANTUAN PHET SIMULATION TERHADAP KEMAMPUAN PEMECAHAN MASALAH SISWA
Authors: Amanah Lutfiyatul , Ardani Anwar , Purwaningsih Dian
Published: November 2023

Rendahnya kemampuan pemecahan masalah siswa melatarbelakangi peneliti melakukan penelitian. Tujuan penelitian ini untuk mengetahui apakah pembelajaran dengan menggunakan model pembelajaran simulasi berbantuan PhET Simulation lebih baik dari model pembelajaran konvensional jika dalam kemampuan pemecahan masalah siswa, dan untuk mengetahui apakah ada peningkatan kemampuan pemecahan masalah siswa sebelum dengan setelah menggunakan model pembelajaran simulasi berbantuan PhET Simulation. Metode yang digunakan adalah metode eksperimen dengan desain penelitian quasi experimental. Populasi dalam penelitian ini adalah siswa kelas IV dua SD Negeri se-Desa Mlayang, dengan sampel siswa kelas IV SD Negeri Mlayang 02 sebagai kelas eksperimen dan siswa kelas IV SD Negeri Mlayang 01 sebagai kelas kontrol. Teknik pengumpulan data menggunakan observasi, wawancara, dokumentasi, dan tes. Teknik analisis data yang digunakan yaitu independent sample t test dan paired sample t test. Hasil penelitian menunjukkan bahwa (1)  yaitu , (2)  yaitu , sehingga dapat disimpulkan bahwa (1) kemampuan pemecahan masalah siswa yang diajar menggunakan model pembelajaran simulasi berbantuan PhET Simulation lebih baik dibandingkan dengan yang diajar menggunakan model pembelajaran konvensional, dan (2) terdapat peningkatan kemampuan pemecahan masalah siswa sebelum dengan setelah menggunakan model pembelajaran simulasi berbantuan PhET Simulation. Kata Kunci: Efektivitas, Model Pembelajaran Simulasi, Media PhET Simulation, Kemampuan Pemecahan Masalah
Strategi Media Lokal di Era Pasca Pandemi: Studi Kasus Harian Bhirawa di Surabaya
Authors: Herdono Ismojo , Bungin Burhan , Wono Hilda Yunita
Published: November 2023

The impacts of Covid-19 Pandemic seems not only ruin the various joints of human lie. But also it has an impact on the life of the mass media industry. Both print media, online media and electronica media (radio and television). Not a few media that were forced to “lay off” their employees and forced to out of bussiness.

This research aims to determine how Harian Bhirawa’s strategic, a local media in Surabaya, be able to survive in Covid-19 Post Pandemic Era. This qulitative research was conducted through a case study, with a media organizing management perspective, specifically techniques, programs, marketing and human resources.

The results of this research indicates, that Harian Bhirawa is able to elaborate the marketing and human resources divisions to partner and to get financial benefits from Goverment of East Java Province. As part of the mass media that should adapts to advances in information technology (technorealist), Harian Bhirawa is able to survive without having to “sacrifice” its criticality, and is able to act as a media of education (to educate), information (to infrom), and entertaiment (to intertaint)

Key Words : Media strategic, case study, bhirawa daily, media organizing management
Drone journalism: praktiknya dalam foto jurnalistik di Indonesia
Authors: Wijaya Taufan , Ariyanti Ratna
Published: November 2023

Salah satu pencarian berita visual yang tergolong mutakhir adalah penggunaan Unmanned Aerial Vehicles (UAVs) atau drone. Pengunaan drone untuk reportase semakin banyak seiring teknologi drone yang semakin murah. Banyaknya penggunaan drone tersebut juga berlangsung di Indonesia, salah satunya pada foto jurnalistik. Penelitian ini berfokus pada penggunaan drone dalam praktik foto jurnalistik di Indonesia dengan menggunakan metode purposive sampling di mana wawancara dilakukan secara mendalam. Dengan menggunakan wawancara dan bukti tambahan lain berupa studi dokumen dan pengamatan, tren penggunaan drone ini diuji untuk mengeksplorasi bagaimana foto ketinggian menjadi kebutuhan baru bagi kerja jurnalis foto lalu aspek etis dan regulasinya. Temuan dari makalah ini akan membantu jurnalis foto dan media untuk melihat tren dan menyesuaikan kebutuhan visual di media mereka bekerja.

Kata Kunci: Drone, Unmanned Aerial Vehicles, Drone Journalism, Foto Jurnalistik.
Representasi gay dalam film pendek pria: kajian semiotik pierce
Authors: Riswari Aninditya Ardhana
Published: November 2023

Kehadiran film sebagai media yang merepresentasikan kehidupan kemasyarakatan rupanya turut menyajikan sesuatu yang dianggap tabu. Seperti dalam film Pria yang menyajikan gambaran atas kehidupan sosok lelaki dengan orientasi seksual yang berbeda, di mana sang tokoh utama merasakan pergolakan batin atas sesuatu yang dirasakan terkait ketertarikan terhadap sesama jenis. Untuk itu penelitian ini disusun dengan tujuan menganalisis representasi gay dalam film pendek Pria melalui kajian semiotik Pierce. Penelitian ini disusun dengan menggunakan metode kualitatif yang dipadu dengan penggunaan teori Pierce, di mana tersusun analisis antara simbol dan lambang yang hadir untuk memunculkan makna. Hasil penelitian menunjukkan bahwa setiap adegan yang muncul dalam film Pria menjadi simbol atas pemaknaan “keberbedaan” orientasi seksual yang dirasakan oleh Aris. Kehadiran kaos yang digunakan di atas rambut hingga ekor kuda menjadi lambang atas petanda yang menghadirkan makna baru mengenai kehadiran gay dalam konteks masyarakat tradisional. Untuk itu dapat disimpulkan bahwa rekaan dan adegan yang muncul dalam film Pria mengisyaratkan simbol-simbol sebagai penanda untuk menguak sesuatu yang mewakili sesuatu lain, yang dalam hal ini berkaitan dengan orientasi seksual yakni gay.
Semiotika dalam website olympics.com: komunikasi tim campuran panahan korea selatan di olimpiade tokyo 2020
Authors: Putranto Teguh Dwi
Published: November 2023

The success of each athlete in obtaining peak performance during competition depends on the players' and coaches' ability to communicate. When participating in practices and games, communication is crucial and cannot be neglected. In both individual and team events during archery competitions, communication becomes more and more intense. This study looked at how the South Korean archery team's athletes and coaches communicated during the 2020 Tokyo Olympics. Using semiotics (Peirce), South Korean archery teams' performances in the finals of two competitions (mixed team and men/women team) were examined. The results of this research showed that communication between the archers and their coaches was dominated by non-verbal communication in mixed team’s numbers symbolised by the high five.
CONSIDERAÇÕES CLÍNICAS E MANEJO ODONTOLÓGICO DE PACIENTES COM DOENÇA RENAL CRÔNICA
Authors: Emilly Katley Ferreira Rodrigues , Basílio Rodrigues Vieira , Eugênia Lívia de Andrade Dantas
Published: November 2023

Chronic Kidney Disease (CKD) is characterized by the slow and irreversible destruction of the nephrons, compromising glomerular filtration and promoting the accumulation of toxic substances in the blood. Initially, the diagnosis is made only by hematological tests, but as the condition advances, the signs and symptoms become more evident and the replacement renal therapy becomes necessary. Approximately 90% of patients have some oral symptom resulting from the disease, the effects of treatment, or negligence of oral hygiene measures. This study aims to review the literature about CKD, discuss its implications on the oral condition of patients and present a protocol that allows safe and effective dental care. The review was done using the databases Medline, SciELO and LILACS limiting the search to the period 2010 to 2020, using the descriptors: “Chronic Kidney Failure”, “Dental Care” and “Oral Alterations”. It is important that the dentist knows the systemic condition of CKD and how it reflects on the oral health, thus, he will be able to choose the ideal conduct for dental care, which must happen from prevention to clinical therapy in order to promote a better quality of life for these patients.
Comparing Porocarcinoma Outcomes Following Resection by Surgical Management Technique
Authors: Shope Chelsea , Andrews Laura , Robinson-Pirotte India , Forcucci Jessica
Published: November 2023

Introduction
Porocarcinoma is a neoplasm of eccrine sweat glands. While wide local excision (WLE) has traditionally been the surgical technique of choice for porocarcinoma resection, the number of cases treated using Mohs micrographic surgery (MMS) is increasing.
Methods
We performed a retrospective review of patients diagnosed with porocarcinoma from January 2015 - February 2020. Chi-square and Fisher’s exact test was used to evaluate outcomes.
Results
Twelve patients were evaluated following surgical treatment. WLE recipients were younger, with an equal number of white and black patients. All MMS patients were white (4). Both WLE and MMS were most performed on the head and neck (6 and 3, respectively). Local recurrence rate was 12.5% in the WLE group (vs. 0% for MMS). Mortality rate was 25% for each group.
Discussion
Prognosis following WLE is poor. Our results suggest that MMS is a useful modality for the surgical treatment of porocarcinoma.
A Case of Angiolymphoid Hyperplasia with Eosinophilia Treated with Combination Therapy of Topical and Intralesional Corticosteroids
Authors: Marushchak Olga , Shah Nehal , Jacobson Mark , Ros Adriana
Published: November 2023

Angiolymphoid hyperplasia with eosinophilia is an uncommon, benign vasoproliferative disorder that can present with single or multiple pink to red-brown dome shaped papules, predominantly on the head and neck. The most common reported symptoms include, but are not limited to, pruritus, bleeding and pain. Currently, there is no definitive treatment for this condition, with numerous therapeutic modalities described in the literature. The most effective and commonly used treatment is excision but can be more invasive and still has a high failure rate (40.3%). Despite the high failure rates associated with topical, systemic and Intralesional corticosteroids, we were able to show significant improvement with the combination of topical and Intralesional corticosteroids. This form of therapy is considerably cheaper and non-invasive compared to alternative therapies. Given the high recurrence and lack of definitive treatments, more research is needed for a better understanding of pathophysiology and identification of effective therapies.
Successful Treatment of Unilateral Hailey-Hailey Disease
Authors: Zambrano Angelica , Ramirez Fabiola , Guevara Adrian , Worrell John
Published: November 2023

Hailey-Hailey Disease is a notoriously difficult to treat genodermatosis. While several treatment modalities are available, successful treatment of recalcitrant disease is not well documented. Superficial radiotherapy, a treatment typically reserved for skin cancer, has recently been utilized to treat Hailey-Hailey disease. In this case report we present the successful treatment of Hailey-Hailey disease in a patient with an unusual unilateral multifocal presentation. Based on the results of this case report, we believe SRT has strong potential to become the standard of care for recalcitrant HHD. Though there are risks to this treatment, the overall risks are minor compared to the decades of antibiotics, recurring infections, long term scarring and loss of self-esteem that arise from chronic recalcitrant HHD.
Development of Multiple Facial Lipomas During Immunotherapy for Metastatic Squamous Cell Carcinoma
Authors: Hall Kathryn , Guevara Adrian
Published: November 2023

An 85-year-old Caucasian male on immunotherapy for metastatic squamous cell carcinoma presented with enlarging lipomas in the area of his previous invasive squamous cell carcinoma of the lower lip and chin, status post resection, reconstruction and local radiation.  The development of multiple lipomas during immunotherapy is a novel association which has yet to be reported in the literature.  We discuss a putative mechanism of action of pembrolizumab-induced lipomas and describe the patient's clinical course.