bluuebunny/crossref_metadata_2025 huggingface dataset:
Process Performance Analysis and Improvement for the Manufacture of 6063 Aluminum Alloy
Authors: Hsu Chang-Hsien
Published: May 2020

As industrial manufacturing technologies continuously improve, many conventional industrial materials are struggling to meet the needs of today’s industries. Aluminum alloys are currently the most extensively used non-ferrous metal in the industry, whose properties include corrosion resistance, high strength, and high ductility. As a result, they are widely used in many products, such as doors and windows, vehicles, and electronics. Pure aluminum though, is a very soft, silver-white metal, so to increase its strength, aluminum alloy manufacturers add in various chemical elements (such as magnesium, silicon, and zinc) according to international standards, and then adjust the proportions based on customer needs. If the chemical element composition does not meet specification requirements, it will affect the quality of the aluminum alloy product or even delay delivery and subsequently impact the operational performance of the manufacturer. To ensure and increase aluminum alloy quality, this study used a combined Six Sigma quality index (SSQI), Qpc, to develop a multi-characteristic quality analysis model (MCQAM) with five steps for the aluminum alloy industry. A practical example with a manufacturer specializing in producing 6063 aluminum alloys in Taiwan is given to demonstrate the effectiveness and feasibility of this proposed approach. The result shows that the proposed method not only effectively improves the quality of 6063 aluminum alloy, but also enhances its performance and capability (that is, corrosion resistance increases by 17%, strength increases by 8%, and stiffness increases by 3%). Finally, future works are also discussed in this context.
Editorial for the Special Issue on Micro/Nano-Chip Electrokinetics, Volume III
Authors: Qian Shizhi , Xuan Xiangchun
Published: May 2020

With the support from contributors and the help from peer reviewers, the Special Issue on Micro/Nano-Chip Electrokinetics (Volume III) published fourteen regular research articles and one review article [...]
The Effect of 4′-hydroxy-3,4,5-trimetoxystilbene, the Metabolite of Resveratrol Analogue DMU-212, on Growth, Cell Cycle and Apoptosis in DLD-1 and LOVO Colon Cancer Cell Lines
Authors: Jozkowiak Malgorzata , Skupin-Mrugalska Paulina , Nowicki Andrzej , Borys-Wojcik Sylwia , Wierzchowski Marcin , Kaczmarek Mariusz , Ramlau Piotr , Jodynis-Liebert Jadwiga , Piotrowska-Kempisty Hanna
Published: May 2020

Resveratrol is a phytoalexin that naturally occurs in grapes, blueberries, cranberries, peanuts and many other plants. Although resveratrol inhibits carcinogenesis in all three stages, its clinical application is restricted due to poor pharmacokinetics. The methylated analogues of resveratrol have been found to have higher bioavailability and cytotoxic activity than that of the prototupe compound. Among the various methoxy derivatives of resveratrol, 3,4,5,4′-tetrametoxystilbene (DMU-212) is suggested to be one of the strongest activators of cytotoxicity and apoptosis. DMU-212 has been shown to exert anti-tumor activity in DLD-1 and LOVO colon cancer cells. Since colorectal cancer is the third most common cause of cancer-related deaths worldwide, the development of new anticancer agents is nowadays of high significance. The aim of the present study was to assess the anticancer activity of 4′-hydroxy-3,4,5-trimetoxystilbene (DMU-281), the metabolite of DMU-212, in DLD-1 and LOVO cell lines. We showed for the first time the cytotoxic activity of DMU-281 triggered via cell cycle arrest at G2/M phase and apoptosis induction accompanied by the activation of caspases-9, -8, -3/7. Furthermore, DMU-281 has been found to change the expression pattern of genes and proteins related to intrinsic as well as extrinsic apoptosis. Since the activation of these pathways of apoptosis is still the most desired strategy in anticancer research, DMU-281 seems to provide a promising approach to the treatment of colon cancer.
Potent In Vitro Activity of Citrus aurantium Essential Oil and Vitis vinifera Hydrolate Against Gut Yeast Isolates from Irritable Bowel Syndrome Patients—The Right Mix for Potential Therapeutic Use
Authors: Di Vito Maura , Bellardi Maria Grazia , Sanguinetti Maurizio , Mondello Francesca , Girolamo Antonietta , Barbanti Lorenzo , Garzoli Stefania , Sabatino Manuela , Ragno Rino , Vitali Alberto , Palucci Ivana , Posteraro Brunella , Gasbarrini Antonio , Prati Gian Maria , Aragona Giovanni , Mattarelli Paola , Bugli Francesca
Published: May 2020

Background: Irritable bowel syndrome (IBS) is a functional disorder without any pathological alteration, in which the alterations of the Candida/Saccharomyces ratio of the gut microbiota, the balance of pro and anti-inflammatory cytokines and the brain-gut-microbiome axis are important for the development and progression of IBS. The aim of the study was to identify natural products, including essential oils or hydrolates, which were contextually harmless for the gut beneficial strains (e.g., Saccharomyces spp.) but inhibitory for the pathogenic ones (Candida spp.). Methods: The effectiveness of 6 essential oils and 2 hydrolates was evaluated using microbiological tests, carried out on 50 clinical isolates (Candida, Saccharomyces and Galattomyces species) and 9 probiotic strains (Saccharomyces cerevisiae, Lactobacillus species, Akkermansia muciniphila and Faecalibacterium prausnitzii) and immunological and antioxidant assays. Results: The study led to a mixture based on a 1/100 ratio of Citrus aurantium var. amara essential oil / Vitis vinifera cv Italia hydrolate able to contextually reduce, in a concentration-dependent manner, the ability of Candida species to form hyphal filaments and have an interesting immunomodulatory and anti-oxidant action. This mixture can potentially be useful in the IBS treatment promoting the restoration of the intestinal microbial and immunological balance.
Trimethylamine N-Oxide in Relation to Cardiometabolic Health—Cause or Effect?
Authors: Papandreou Christopher , Moré Margret , Bellamine Aouatef
Published: May 2020

Trimethylamine-N-oxide (TMAO) is generated in a microbial-mammalian co-metabolic pathway mainly from the digestion of meat-containing food and dietary quaternary amines such as phosphatidylcholine, choline, betaine, or L-carnitine. Fish intake provides a direct significant source of TMAO. Human observational studies previously reported a positive relationship between plasma TMAO concentrations and cardiometabolic diseases. Discrepancies and inconsistencies of recent investigations and previous studies questioned the role of TMAO in these diseases. Several animal studies reported neutral or even beneficial effects of TMAO or its precursors in cardiovascular disease model systems, supporting the clinically proven beneficial effects of its precursor, L-carnitine, or a sea-food rich diet (naturally containing TMAO) on cardiometabolic health. In this review, we summarize recent preclinical and epidemiological evidence on the effects of TMAO, in order to shed some light on the role of TMAO in cardiometabolic diseases, particularly as related to the microbiome.
Maternal Caffeine Intake Disrupts Eggshell Integrity and Retards Larval Development by Reducing Yolk Production in a Caenorhabditis elegans Model
Authors: Min Hyemin , Youn Esther , Shim Yhong-Hee
Published: May 2020

During pregnancy, most women are exposed to caffeine, which is a widely consumed psychoactive substance. However, the consequences of maternal caffeine intake on the child remain largely unknown. Here, we investigated the intergenerational effects of maternal caffeine intake on offspring in a Caenorhabditis elegans model. We treated a young mother (P0) with 10 mM of caffeine equivalent to 2–5 cans of commercial energy drinks and examined its reproduction and growth rate from P0 to F2 generation. The fertility decreased and embryonic lethality increased by defective oocytes and eggshell integrity in caffeine-ingested mothers, and F1 larval development severely retarded. These results were due to decreased production of vitellogenin protein (yolk) in caffeine-ingested mothers. Furthermore, effects of RNA interference of vitellogenin (vit) genes, vit-1 to vit-6, in P0 mothers can mimic those by caffeine-ingested mothers. In addition, RNA interference (RNAi) depletion of unc-62 (human Meis homeobox), a transcriptional activator for vit genes, also showed similar effects induced by caffeine intake. Taken together, maternal caffeine intake reduced yolk production mediated by the UNC-62 transcription factor, thereby disrupting oocyte and eggshell integrity and retarding larval development. Our study suggests the clinical significance of caffeine intake for prospective mothers.
Role of Fermented Goat Milk on Liver Gene and Protein Profiles Related to Iron Metabolism during Anemia Recovery
Authors: Moreno-Fernandez Jorge , Alférez María J. M. , López-Aliaga Inmaculada , Díaz-Castro Javier
Published: May 2020

Despite the crucial role of the liver as the central regulator of iron homeostasis, no studies have directly tested the modulation of liver gene and protein expression patterns during iron deficiency instauration and recovery with fermented milks. Fermented goat milk consumption improves the key proteins of intestinal iron metabolism during iron deficiency recovery, enhancing the digestive and metabolic utilization of iron. The aim of this study was to assess the influence of fermented goat or cow milk consumption on liver iron homeostasis during iron-deficiency anemia recovery with normal or iron-overload diets. Analysis included iron status biomarkers, gene and protein expression in hepatocytes. In general, fermented goat milk consumption either with normal or high iron content up-regulated liver DMT1, FPN1 and FTL1 gene expression and DMT1 and FPN1 protein expression. However, HAMP mRNA expression was lower in all groups of animals fed fermented goat milk. Additionally, hepcidin protein expression decreased in control and anemic animals fed fermented goat milk with normal iron content. In conclusion, fermented goat milk potentiates the up-regulation of key genes coding for proteins involved in iron metabolism, such as DMT1, and FPN1, FTL1 and down-regulation of HAMP, playing a key role in enhanced iron repletion during anemia recovery, inducing a physiological adaptation of the liver key genes and proteins coordinated with the fluctuation of the cellular iron levels, favoring whole-body iron homeostasis.
Nutraceuticals in Thyroidology: A Review of in Vitro, and in Vivo Animal Studies
Authors: Benvenga Salvatore , Ferrari Silvia Martina , Elia Giusy , Ragusa Francesca , Patrizio Armando , Paparo Sabrina Rosaria , Camastra Stefania , Bonofiglio Daniela , Antonelli Alessandro , Fallahi Poupak
Published: May 2020

Nutraceuticals are defined as a food, or parts of a food, that provide medical or health benefits, including the prevention of different pathological conditions, and thyroid diseases, or the treatment of them. Nutraceuticals have a place in complementary medicines, being positioned in an area among food, food supplements, and pharmaceuticals. The market of certain nutraceuticals such as thyroid supplements has been growing in the last years. In addition, iodine is a fundamental micronutrient for thyroid function, but also other dietary components can have a key role in clinical thyroidology. Here, we have summarized the in vitro, and in vivo animal studies present in literature, focusing on the commonest nutraceuticals generally encountered in the clinical practice (such as carnitine, flavonoids, melatonin, omega-3, resveratrol, selenium, vitamins, zinc, and inositol), highlighting conflicting results. These experimental studies are expected to improve clinicians’ knowledge about the main supplements being used, in order to clarify the potential risks or side effects and support patients in their use.
Discordant Dose-Dependent Metabolic Effects of Eicosapentanoic Acid in Diet-Induced Obese Mice
Authors: Pahlavani Mandana , Ramalingam Latha , Miller Emily K. , Davis Hanna , Scoggin Shane , Moustaid-Moussa Naima
Published: May 2020

Obesity is a widespread epidemic that increases the risk for several metabolic diseases. Despite several beneficial health effects of eicosapentaenoic acid (C20:5n-3, EPA), previous studies have used very high doses of EPA. In this study, dose-dependent effects of EPA on metabolic outcomes were determined in diet-induced obese mice. We used B6 male mice, fed high-fat diet (HF, 45% kcal fat) or HF diet supplemented with 9, 18, and 36 g/kg of EPA-enriched fish oil for 14 weeks. We conducted metabolic phenotyping during the feeding period, and harvested tissues and blood at termination. Only mice fed 36 g/kg of EPA significantly (p < 0.05) lowered body weight, fat content and epididymal fat pad weight, compared to HF. Both 18 and 36 g/kg doses of EPA significantly increased glucose clearance and insulin sensitivity, compared to HF or 9 g/kg of EPA. Locomotor activity was significantly increased with both 18 and 36 g/kg doses of EPA. Interestingly, all doses of EPA compared to HF, significantly increased energy expenditure and oxygen consumption and significantly reduced serum insulin, leptin, and triglycerides levels. These results demonstrate weight- and adiposity-independent metabolic benefits of EPA, at doses comparable to those currently used to treat hypertriglyceridemia.
Polyphenols as Caloric-Restriction Mimetics and Autophagy Inducers in Aging Research
Authors: Yessenkyzy Assylzhan , Saliev Timur , Zhanaliyeva Marina , Masoud Abdul-Razak , Umbayev Bauyrzhan , Sergazy Shynggys , Krivykh Elena , Gulyayev Alexander , Nurgozhin Talgat
Published: May 2020

It has been thought that caloric restriction favors longevity and healthy aging where autophagy plays a vital role. However, autophagy decreases during aging and that can lead to the development of aging-associated diseases such as cancer, diabetes, neurodegeneration, etc. It was shown that autophagy can be induced by mechanical or chemical stress. In this regard, various pharmacological compounds were proposed, including natural polyphenols. Apart from the ability to induce autophagy, polyphenols, such as resveratrol, are capable of modulating the expression of pro- and anti-apoptotic factors, neutralizing free radical species, affecting mitochondrial functions, chelating redox-active transition metal ions, and preventing protein aggregation. Moreover, polyphenols have advantages compared to chemical inducers of autophagy due to their intrinsic natural bio-compatibility and safety. In this context, polyphenols can be considered as a potential therapeutic tool for healthy aging either as a part of a diet or as separate compounds (supplements). This review discusses the epigenetic aspect and the underlying molecular mechanism of polyphenols as an anti-aging remedy. In addition, the recent advances of studies on NAD-dependent deacetylase sirtuin-1 (SIRT1) regulation of autophagy, the role of senescence-associated secretory phenotype (SASP) in cells senescence and their regulation by polyphenols have been highlighted as well. Apart from that, the review also revised the latest information on how polyphenols can help to improve mitochondrial function and modulate apoptosis (programmed cell death).
Assessing the Healthy Food Partnership’s Proposed Nutrient Reformulation Targets for Foods and Beverages in Australia
Authors: Rosewarne Emalie , Huang Liping , Farrand Clare , Coyle Daisy , Pettigrew Simone , Jones Alexandra , Moore Michael , Webster Jacqui
Published: May 2020

Non-communicable diseases (NCDs) are the leading cause of mortality and morbidity worldwide. Unhealthy diets are one of four main behavioral risk factors contributing to the majority of NCDs. To promote healthy eating and reduce dietary risks, the Australian Commonwealth Government established the Healthy Food Partnership (HFP). In 2018, the HFP consulted on proposed nutrient reformulation targets for 36 food categories to improve the overall quality of the food supply. This study assessed whether the proposed targets were feasible and appropriate. The HFP used a five-step approach to inform the proposed targets. We replicated and extended this approach using a different nutrient composition database (FoodSwitch). Products in FoodSwitch were mapped to the proposed HFP targets. The proportion of products meeting each target was calculated and the FoodSwitch data were compared with HFP data to determine whether the proposed target nutrient levels were appropriate or whether a more stringent target was feasible. Products from the FoodSwitch database (10,599) were mapped against the proposed HFP categories: 8434 products across 30 categories for sodium, 2875 products across seven categories for sugar, and 612 products across five categories for saturated fat. The analyses revealed that 14 of 30 proposed HFP targets for sodium, one of seven targets for sugar, and one of five targets for saturated fat were feasible and appropriate. For the remaining 26 reformulation targets, the results indicate that these target levels could be more stringent and alternative targets are proposed. The draft HFP targets are feasible but the majority are too conservative. If Australia is to meet its commitment to a 30 per cent reduction in the average population salt intake by 2025, these targets could be implemented as interim targets to be reached within two years. However, the opportunity exists to improve the food supply and strengthen the HFP’s population health impact by adopting more ambitious and incremental targets. Reformulation programs should be prioritized and closely monitored as part of a coordinated, multi-faceted national food and nutrition strategy.
High Intake of Sugar and the Balance between Pro- and Anti-Inflammatory Gut Bacteria
Authors: Satokari Reetta
Published: May 2020

The so-called Western diet is rich in saturated fat and sugars and poor in plant-derived fibers, and it is associated with an increased risk of metabolic and cardiovascular diseases, as well as chronic (low grade) inflammation. The detrimental effects of poor diet are in part mediated by gut microbiota, whose composition, functionality and metabolic end products respond to dietary changes. Recent studies have shown that high intake of sugars increase the relative abundance of Proteobacteria in the gut, while simultaneously decreasing the abundance of Bacteroidetes, which can mitigate the effects of endotoxin, as well as reinforce gut barrier function. Thus, a high sugar intake may stagger the balance of microbiota to have increased pro-inflammatory properties and decreased the capacity to regulate epithelial integrity and mucosal immunity. Consequently, high dietary sugar can, through the modulation of microbiota, promote metabolic endotoxemia, systemic (low grade) inflammation and the development of metabolic dysregulation and thereby, high dietary sugar may have many-fold deleterious health effects, in addition to providing excess energy.
Coffee Consumption and C-Reactive Protein Levels: A Systematic Review and Meta-Analysis
Authors: Moua Elizabeth D. , Hu Chenxiao , Day Nicole , Hord Norman G. , Takata Yumie
Published: May 2020

Coffee contains bioactive compounds with anti-inflammatory properties, and its consumption may reduce c-reactive protein (CRP) levels, a biomarker of chronic inflammation. A previous meta-analysis reported no overall association between blood CRP level and coffee consumption by modeling the coffee consumption in categories, with substantial heterogeneity. However, the coffee cup volume was not considered. We conducted a systematic review and dose–response meta-analysis investigating the association between coffee consumption and CRP levels reported in previous observational studies. A dose–response meta-analysis was conducted by mixed-effects meta-regression models using the volume of coffee consumed as metric. Eleven studies from three continents were identified using the PubMed database, totaling 61,047 participants. Three studies with the largest sample sizes observed a statistically significant association between coffee and CRP levels, which was inverse among European and United States (US) women and Japanese men (1.3–5.5% decrease in CRP per 100 mL of coffee consumed) and positive among European men (2.2% increase). Other studies showed no statistically significant associations. When all studies were combined in the dose–response meta-analysis, no statistically significant associations were observed among all participants or when stratified by gender or geographic location, reflecting the conflicting associations reported in the included studies. Further studies are warranted to explore these inconsistent associations.
Cholesterol and Egg Intakes, and Risk of Hypertension in a Large Prospective Cohort of French Women
Authors: MacDonald Conor-James , Madika Anne-Laure , Bonnet Fabrice , Fagherazzi Guy , Lajous Martin , Boutron-Ruault Marie-Christine
Published: May 2020

Purpose: The relationship between egg and cholesterol intakes, and cardiovascular disease is controversial. Meta-analyses indicate that egg consumption is associated with increased cardiovascular disease and mortality, but reduced incidence of hypertension, a major risk factor for cardiovascular disease. This study aims to investigate the associations between consumption of egg and cholesterol, and hypertension risk in a cohort of French women. Methods: We used data from the E3N cohort study, a French prospective population-based study initiated in 1990. From the women in the study, we included those who completed a detailed diet history questionnaire, and who did not have prevalent hypertension or cardiovascular disease at baseline, resulting in 46,424 women. Hypertension cases were self-reported. Egg and cholesterol intake was estimated from dietary history questionnaires. Cox proportional hazard models with time-updated exposures were used to calculate hazard ratios. Spline regression was used to determine any dose–respondent relationship. Results: During 885,321 person years, 13,161 cases of incident hypertension were identified. Higher cholesterol consumption was associated with an increased risk of hypertension: HRQ1–Q5 = 1.22 [1.14:1.30], with associations similar regarding egg consumption up to seven eggs per week: HR4–7 eggs = 1.14 [1.06:1.18]. Evidence for a non-linear relationship between hypertension and cholesterol intake was observed. Conclusions: Egg and cholesterol intakes were associated with a higher risk of hypertension in French women. These results merit further investigation in other populations.
Mesoporous Silica Nanoparticles as Carriers for Therapeutic Biomolecules
Authors: Castillo Rafael R. , Lozano Daniel , Vallet-Regí María
Published: May 2020

The enormous versatility of mesoporous silica nanoparticles permits the creation of a large number of nanotherapeutic systems for the treatment of cancer and many other pathologies. In addition to the controlled release of small drugs, these materials allow a broad number of molecules of a very different nature and sizes. In this review, we focus on biogenic species with therapeutic abilities (proteins, peptides, nucleic acids, and glycans), as well as how nanotechnology, in particular silica-based materials, can help in establishing new and more efficient routes for their administration. Indeed, since the applicability of those combinations of mesoporous silica with bio(macro)molecules goes beyond cancer treatment, we address a classification based on the type of therapeutic action. Likewise, as illustrative content, we highlight the most typical issues and problems found in the preparation of those hybrid nanotherapeutic materials.
Activation Energies and Temperature Dependencies of the Rates of Crystallization and Melting of Polymers
Authors: Vyazovkin Sergey
Published: May 2020

The objective of this review paper is to survey the phase transition kinetics with a focus on the temperature dependence of the rates of crystallization and melting, as well as on the activation energies of these processes obtained via the Arrhenius kinetic treatment, including the treatment by isoconversional methods. The literature is analyzed to track the development of the basic models and their underlying concepts. The review presents both theoretical and practical considerations regarding the kinetic analysis of crystallization and melting. Both processes are demonstrated to be kinetically complex, and this is revealed in the form of nonlinear Arrhenius plots and/or the variation of the activation energy with temperature. Principles which aid one to understand and interpret such results are discussed. An emphasis is also put on identifying proper computational methods and experimental data that can lead to meaningful kinetic interpretation.
Potential Natural Fiber Polymeric Nanobiocomposites: A Review
Authors: Hasan K. M. Faridul , Horváth Péter György , Alpár Tibor
Published: May 2020

Composite materials reinforced with biofibers and nanomaterials are becoming considerably popular, especially for their light weight, strength, exceptional stiffness, flexural rigidity, damping property, longevity, corrosion, biodegradability, antibacterial, and fire-resistant properties. Beside the traditional thermoplastic and thermosetting polymers, nanoparticles are also receiving attention in terms of their potential to improve the functionality and mechanical performances of biocomposites. These remarkable characteristics have made nanobiocomposite materials convenient to apply in aerospace, mechanical, construction, automotive, marine, medical, packaging, and furniture industries, through providing environmental sustainability. Nanoparticles (TiO2, carbon nanotube, rGO, ZnO, and SiO2) are easily compatible with other ingredients (matrix polymer and biofibers) and can thus form nanobiocomposites. Nanobiocomposites are exhibiting a higher market volume with the expansion of new technology and green approaches for utilizing biofibers. The performances of nanobiocomposites depend on the manufacturing processes, types of biofibers used, and the matrix polymer (resin). An overview of different natural fibers (vegetable/plants), nanomaterials, biocomposites, nanobiocomposites, and manufacturing methods are discussed in the context of potential application in this review.
Photosensitive Poly-l-lysine/Heparin Interpolyelectrolyte Complexes for Delivery of Genetic Drugs
Authors: Korzhikov-Vlakh Viktor , Katernuk Iuliia , Pilipenko Iuliia , Lavrentieva Antonina , Guryanov Ivan , Sharoyko Vladimir , Manshina Alina A. , Tennikova Tatiana B.
Published: May 2020

Photo-triggered release of biopharmaceutical drugs inside the cells is a challenging direction of modern science, which requires obtaining new polymeric systems. The interpolyelectrolyte complexes (IPECs) of poly-l-lysine with heparin capable of encapsulation of genetic constructions—such as model oligonucleotide, siRNA, and pDNA—were obtained. Poly-l-lysine to heparin ratios were optimized to provide the appropriate release kinetics of genetic material from the polyplex. In order to impart the obtained IPEC with photosensitive properties, the linker was synthesized as based on 4-brommethyl-3-nitrobenzoic acid. The conditions and kinetics of photosensitive linker destruction were carefully studied. The colloid particles of IPEC were modified with Cy3 probe and their cellular internalization was investigated by flow cytometry method. The efficacy of photosensitive IPECs as siRNA and pDNA delivery system was evaluated.
Characterization of the High-Resolution Infrared Radiation Sounder Using Lunar Observations
Authors: Burgdorf Martin J. , Müller Thomas G. , Buehler Stefan A. , Prange Marc , Brath Manfred
Published: May 2020

The High-Resolution Infrared Radiation Sounder (HIRS) has been operational since 1975 on different satellites. In spite of this long utilization period, the available information about some of its basic properties is incomplete or contradictory. We have approached this problem by analyzing intrusions of the Moon in the deep space view of HIRS/2 through HIRS/4. With this method we found: (1) The diameters of the field of view of HIRS/2, HIRS/3, and HIRS/4 have the relative proportions of 1.4 ° to 1.3 ° to 0.7 ° with all channels; (2) the co-registration differs by up to 0.031 ° among the long-wave and by up to 0.015 ° among the shortwave spectral channels in the along-track direction; (3) the photometric calibration is consistent within 0.7% or less for channels 2–7 (1.2% for HIRS/2), similar values were found for channels 13–16; (4) the non-linearity of the short-wavelength channels is negligible; and (5) the contribution of reflected sunlight to the flux in the short-wavelength channels can be determined in good approximation, if the emissivity of the surface is known.
A Hyperspectral-Physiological Phenomics System: Measuring Diurnal Transpiration Rates and Diurnal Reflectance
Authors: Weksler Shahar , Rozenstein Offer , Haish Nadav , Moshelion Menachem , Walach Rony , Ben-Dor Eyal
Published: May 2020

A novel hyperspectral-physiological system that monitors plants dynamic response to abiotic alterations was developed. The system is a sensor-to-plant platform which can determine the optimal time of day during which physiological traits can be successfully identified via spectral means. The directly measured traits include momentary and daily transpiration rates throughout the daytime and daily and periodical plant weight loss and gain. The system monitored and evaluated pepper plants response to varying levels of potassium fertilization. Significant momentary transpiration rates differences were found between the treatments during 07:00–10:00 and 14:00–17:00. The simultaneous frequently measured high-resolution spectral data provided the means to correlate the two measured data sets. Significant correlation coefficients between the spectra and momentary transpiration rates resulted with a selection of three bands (ρ523, ρ697 and ρ818nm) that were used to capture transpiration rate differences using a normalized difference formula during the morning, noon and the afternoon. These differences also indicated that the best results are not always obtained when spectral (remote or proximal) measurements are typically preformed around noon (when solar illumination is the highest). Valuable information can be obtained when the spectral measurements are timed according to the plants’ dynamic physiological status throughout the day, which may vary among plant species and should be considered when planning remote sensing data acquisition.
FORUM Earth Explorer 9: Characteristics of Level 2 Products and Synergies with IASI-NG
Authors: Ridolfi Marco , Del Bianco Samuele , Di Roma Alessio , Castelli Elisa , Belotti Claudio , Dandini Paolo , Di Natale Gianluca , Dinelli Bianca Maria , C.-Labonnote Laurent , Palchetti Luca
Published: May 2020

FORUM (Far-infrared Outgoing Radiation Understanding and Monitoring) has been approved to be the ninth Earth Explorer mission of the European Space Agency. The mission is scheduled for launch on a Polar satellite in the 2025–2026 time frame. The core FORUM instrument is a Fourier Transform Spectrometer measuring, with very high accuracy, the upwelling spectral radiance, from 100 to 1600 cm − 1 (from 100 to 6.25 microns in wavelength), thus covering the Far-Infrared (FIR), and a Mid-Infrared (MIR) portion of the spectrum emitted by the Earth. FORUM will fly in loose formation with the MetOp-SG-1A satellite, hosting the Infrared Atmospheric Sounding Interferometer – New Generation (IASI-NG). IASI-NG will measure only the MIR part of the upwelling atmospheric spectrum, from 645 to 2760 cm − 1 (from 15.5 to 3.62 microns in wavelength), thus, the matching FORUM measurements will supply the missing FIR complement. Together, the two missions will provide, for the first time, a spectrally resolved measurement of the full Earth emitted thermal spectrum. The calibrated spectral radiance will be, on its own, the main product of the FORUM mission, however, the radiances will also be processed up to Level 2, to determine the vertical profile of water vapour, surface spectral emissivity and cloud parameters in the case of cloudy atmospheres. In this paper we assess the performance of the FORUM Level 2 products based on clear-sky simulated retrievals and we study how the FORUM and IASI-NG matching measurements can be fused in a synergistic retrieval scheme, to provide improved Level 2 products. Considering only the measurement noise and the systematic calibration error components, we find the following figures for the synergistic FORUM and IASI-NG retrieval products. In the upper troposphere/lower stratosphere region, individual water vapour profiles can be retrieved with 1 km vertical sampling and an error ranging from 10% to 15%. In the range from 300 to 600 cm − 1 , surface spectral emissivity can be retrieved with an absolute error as small as 0.001 in dry Polar atmospheres. Ice cloud parameters such as ice water path and cloud top height can be retrieved with errors smaller than 10% and 1 km, respectively, for ice water path values ranging from 0.2 to 60 g/m 2 .
Assessing the Applicability of Mobile Laser Scanning for Mapping Forest Roads in the Republic of Korea
Authors: Kweon Hyeongkeun , Seo Jung Il , Lee Joon-Woo
Published: May 2020

Forest roads are an essential facility for sustainable forest management and protection. With advances in survey technology, such as Light Detection and Ranging, forest road maps with greater accuracy and resolution can be produced. This study produced a 3D map for establishment of a forest road inventory using a Mobile Laser Scanning (MLS) device mounted on a vehicle in four study forest roads in Korea, in order to review its precision, accuracy and efficiency based on comparisons with mapping using Total Station (TS) and Global Navigation Satellite System (GNSS). We counted the points that consist of the cloud data of the maps to determine the degree of precision density, and then compared this with 50 points at 20-m intervals on the centerlines bisecting the widths of the study forest roads. Then, we evaluated the relative positional accuracy of the MLS data based on three criteria: the total length of each forest road; the Root Mean Square Error (RMSE) obtained from coordinate values of the MLS and TS surveys compared to the GNSS survey; and the ratios of the centerlines extracted by the MLS and TS surveys overlaid to the buffer zone by the GNSS survey. Finally, we estimated the time and cost per unit length for producing the map to examine the efficiency of MLS mapping compared to the other two surveys. The results showed that the point cloud data acquired by the MLS survey on the study forest roads had very high precision and so is sufficient to produce a 3D forest road map with high-precision density and a low RMSE value. Although the equipment rental cost is somewhat high, the fact that information targeting on all spatial elements of forest roads can be obtained with a low cost of labor is a benefit when evaluating the efficiency of MLS survey and mapping. Our findings are expected to provide a quantitative assessment of both maintaining sustainable effectiveness and preventing potential environmental damage of forest roads.
Nanometer-Scale Vibration Measurement Using an Optical Quadrature Interferometer Based on 3 × 3 Fiber-Optic Coupler
Authors: Park Soongho , Lee Juhyung , Kim Younggue , Lee Byeong Ha
Published: May 2020

We propose a nanometer-scale displacement or vibration measurement system, using an optical quadrature interferometer and the post-processing technique that extracts the parameters necessary for characterizing the interferometric system. Using a 3 × 3 fiber-optic coupler, the entire complex interference signal could be reconstructed with two interference signals measured at two return ports of the coupler. The intrinsic phase difference between the return ports was utilized to obtain the quadratic part of the interference signal, which allowed one to reconstruct the entire complex interference signal. However, the two measured signals were appreciably affected by the unequal detector gains and non-uniform intrinsic phases of the coupler. Fortunately, we could find that the Lissajous curve plotted by the two signals of the interferometric system would form an ellipse. Therefore, by fitting the measured Lissajous curve to an ellipse, we could extract the parameters characterizing the actual system, which allowed the nanometer-scale measurement. Experimental results showed that a 20 kHz sinusoidal vibration with an amplitude of 1.5 nm could be measured with a standard deviation of 0.4 nm.
Distributed Target Tracking in Challenging Environments Using Multiple Asynchronous Bearing-Only Sensors
Authors: Shi Yifang , Choi Jee Woong , Xu Lei , Kim Hyung June , Ullah Ihsan , Khan Uzair
Published: May 2020

In the multiple asynchronous bearing-only (BO) sensors tracking system, there usually exist two main challenges: (1) the presence of clutter measurements and the target misdetection due to imperfect sensing; (2) the out-of-sequence (OOS) arrival of locally transmitted information due to diverse sensor sampling interval or internal processing time or uncertain communication delay. This paper simultaneously addresses the two problems by proposing a novel distributed tracking architecture consisting of the local tracking and central fusion. To get rid of the kinematic state unobservability problem in local tracking for a single BO sensor scenario, we propose a novel local integrated probabilistic data association (LIPDA) method for target measurement state tracking. The proposed approach enables eliminating most of the clutter measurement disturbance with increased target measurement accuracy. In the central tracking, the fusion center uses the proposed distributed IPDA-forward prediction fusion and decorrelation (DIPDA-FPFD) approach to sequentially fuse the OOS information transmitted by each BO sensor. The track management is carried out at local sensor level and also at the fusion center by using the recursively calculated probability of target existence as a track quality measure. The efficiency of the proposed methodology was validated by intensive numerical experiments.
Remote Sensing Applications in Coastal Areas
Authors: Lacava Teodosio , Ciancia Emanuele
Published: May 2020

Coastal areas are regions of remarkable relevance for humans, providing essential components for social and economic development from the local to the national scale [...]
Concept for Markerless 6D Tracking Employing Volumetric Optical Coherence Tomography
Authors: Schlüter Matthias , Glandorf Lukas , Gromniak Martin , Saathoff Thore , Schlaefer Alexander
Published: May 2020

Optical tracking systems are widely used, for example, to navigate medical interventions. Typically, they require the presence of known geometrical structures, the placement of artificial markers, or a prominent texture on the target’s surface. In this work, we propose a 6D tracking approach employing volumetric optical coherence tomography (OCT) images. OCT has a micrometer-scale resolution and employs near-infrared light to penetrate few millimeters into, for example, tissue. Thereby, it provides sub-surface information which we use to track arbitrary targets, even with poorly structured surfaces, without requiring markers. Our proposed system can shift the OCT’s field-of-view in space and uses an adaptive correlation filter to estimate the motion at multiple locations on the target. This allows one to estimate the target’s position and orientation. We show that our approach is able to track translational motion with root-mean-squared errors below 0.25 mm and in-plane rotations with errors below 0.3°. For out-of-plane rotations, our prototypical system can achieve errors around 0.6°.
Mercury Phytoremediation with Lolium perenne-Mycorrhizae in Contaminated Soils
Authors: Leudo Ana M. , Cruz Yuby , Montoya-Ruiz Carolina , Delgado María del Pilar , Saldarriaga Juan F.
Published: May 2020

The symbiotic association between the roots of a plant and the mycelium of some fungi is identified as mycorrhizae. Symbiosis helps the plant to obtain nutrients from the soil more efficiently, and may favor the phytoremediation capacity of plants such as Lolium perenne, in soils contaminated with mercury. In this study, the morphological and molecular response was evaluated, as well as the variation in mercury accumulation in the different structures of L. perenne when associated with arbuscular mycorrhizal fungi. Association tests were performed to determine the optimal concentration of the biological inoculant and it was found that the best results were given with the proportion of one part of inoculant in three parts of soil (w/w ratio). The differential expression of the glutathione-S-transferase GST gene was evaluated through real-time PCR and the concentration of heavy metals inside and outside the plant was evaluated with inductively coupled plasma atomic emission spectroscopy (ICP). It was found that the plants that were inoculated with mycorrhizae developed longer stems and shorter roots; in the same way, the GST gene had greater expression in the stem than in the root, largely because the roots help the filtration of nutrients to the stem, retaining metals and detoxifying by GST-catalyzed glutathione.
Optimizing Land Use Allocation of Transit-Oriented Development (TOD) to Generate Maximum Ridership
Authors: Berawi Mohammed Ali , Saroji Gunawan , Iskandar Fuad Adrian , Ibrahim Bernard Elpetino , Miraj Perdana , Sari Mustika
Published: May 2020

Transit-oriented development (TOD) is based around transit stations, with the emphasis on high population density and multifunctional areas in promoting sustainable mobility. This study aimed to develop a TOD model that could achieve an optimum land use allocation to maximize transit ridership. A critical literature review, an analysis of value engineering through function and benchmarking studies were conducted in order to develop a baseline plan for a TOD model, which was then optimized using linear programming. A total of four light rail transit (LRT) stations located in Jakarta were used as the case study to represent model implementation, ridership evaluation and optimal design. The optimization results showed that office workers constituted the highest number of transit passengers, followed by those working in hotels and commercial/retail and residential users. It was also found that optimizing the design of the TOD can increase the number of daily LRT passengers by up to 55%.
Christmas Allowance as a Non-System Tool for Sustainability of Quality of Life of Slovak Seniors
Authors: Vidová Jarmila , Sika Peter
Published: May 2020

Creating conditions for a sustainable level of quality of life for older people is considered the dominant priority when setting up the pension system with an emphasis on the income situation of Slovak seniors for old-age pensions. An old-age pension as a systemic benefit is an important element in maintaining the quality of life of older people. The amount of old-age pensions is currently at the center of discussions between institutions and the Government of the Slovak Republic. A major social but also economic problem in the coming decade will be how to maintain the income of older people, pensioners, needed to ensure their sustainable quality of life. In particular, it is necessary to ensure that pensioners receive sufficient income so that they do not become a population at risk of poverty as the groups at risk of poverty or social exclusion also includes people over the age of 65. The paper focuses on the analysis of the socio-economic situation of Slovak pensioners in the Slovak Republic in connection with material deprivation. At the same time we analyze the Christmas contribution as a non-systemic benefit which, on the one hand, has a positive social impact on the recipients of pension benefits who are entitled to the Christmas benefit but, on the other hand, has a negative impact on the general government budget.
The Care Farming Sector in The Netherlands: A Reflection on Its Developments and Promising Innovations
Authors: Hassink Jan , Agricola Herman , Veen Esther J. , Pijpker Roald , de Bruin Simone R. , Meulen Harold A. B. van der , Plug Lana B.
Published: May 2020

This paper describes the development of care farming in the Netherlands, one of the pioneering countries in this sector, where care farming has developed into a very diverse sector, with some farmers focussing primarily on agricultural production and others more specifically on providing care services. Care farms are increasingly open to a diversity of participants. The sector has become professionalised with the establishment of strong regional organisations and a steady growth increase in revenues, providing employment opportunities and boosting the economy of rural areas. In this paper, we highlight two promising innovations in care farming: education for school dropouts and the establishment of social farming activities in cities. These innovations face the challenge of connecting not only the agricultural and care sectors, but also the educational sector and the urban context. Initiators face a number of challenges, like trying to embed their activities in the educational sector, a mismatch in regulations and a lack of legitimacy in the case of education on care farms, as well as problems gaining access to land and a lack of recognition in the case of social farming in urban areas. However, the prospects are promising in both cases, because they match the changing demands in Dutch society and are able to integrate social, ecological and economic benefits.
Sustainability of Mussel (Mytilus Galloprovincialis) Farming in the Po River Delta, Northern Italy, Based on a Life Cycle Assessment Approach
Authors: Tamburini Elena , Turolla Edoardo , Fano Elisa Anna , Castaldelli Giuseppe
Published: May 2020

Molluscan shellfish aquaculture is considered a “green” industry because of the limited presence of chemicals and risk of pathogens during farming in licensed areas, which provide a safe, nutritive and healthy food source. Moreover, the environmental impact of their production is lower than all other fish animal per unit of protein. In particular, mussels’ production was the first organized mollusk aquaculture in Europe and is now one of the most extended. Italy is the second main European producer of mussels. Taking into account the relevance of the sector, Italian Mediterranean mussel (Mytilus galloprovincialis) aquaculture has been considered for a life cycle assessment (LCA), from a cradle-to-gate perspective. The mussel farms were located in the northern Adriatic Sea, close to the Po River Delta, a region traditionally vocated to bivalve aquaculture. Results have shown that the growing and harvesting phases are the most critical life cycle stages (“hotspots”) due to the production and use of boats, and the great quantity of non-recyclable high-density polyethylene (HDPE) socks used during the yearly productive cycle. Several improvement potentials have been identified and estimated by means of a sensitivity analysis. Furthermore, regarding the principal exporting countries to Italy (Spain and Chile), the transport factors in an overall sustainability assessment have been considered, in order to compare the local and global mussels supply chain.