bluuebunny/crossref_metadata_2025 huggingface dataset:
MANAJEMEN SARANA DAN PRASARANA BRIGHT STAR MAKASSAR SCHOOL DI KECAMATAN TAMALANREA KOTA MAKASSAR
Authors: Patiung Dahlia , Mujahidah Nurul , Nurafia Nurafia , Hayati Nur , Amalia Suci , Ardianti Nur
Published: September 2020

Judul : Sarana dan prasarana Bright Star Makassar School. Dalam judul penilitian ini menggunakan deskriptif kualitatif. Penelitian ini membahas sarana dan prasarana di Bright Star Makassar School. Tujuan dari penelitian ini adalah untuk mengetahui sarana dan prasarana apa saja yang ada di Bright Star Makassar School. Adapun metode penelitian meliputi jenis penelitian, rancangan penelitian, populasi dan sampel, instrument pengumpulan data dan teknik analisis data. Pembahasan dalam penelitian ini meliputi pemeliharaan, alat permainan indoor dan outdoor, ruang kelas, ruang kepala sekolah, ruang guru, perpustakaan permainan, UKS, toilet, tempat wudhu dan pembiayaan. Implikasi penenlitian ini sarana dan prasarana di sekolah Bright Star Makassar School sudah lengkap namun sekolah Bright Star Makassar School dalam tahap renovasi sehingga penggunaan sarana dan prasarana belum digunakan secara maksimal. Adapun jumlah peserta didik di Bright Star Makassar School tersebut sebanyak 156 peserta didik, yang mana jumlah peserta didik di kindergarten sebanyak 53 peserta didik
TINGKAT PENCAPAIAN PADA ASPEK PERKEMBANGAN ANAK USIA DINI 5-6 TAHUN BERDASARKAN STRANDAR NASIONAL PENDIDIKAN ANAK USIA DINI
Authors: Sulaiman Umar , Ardianti Nur , Selviana Selviana
Published: September 2020

Penelitian ini bertujuan untuk mengetahui gambaran tingkat pencapaian perkembangan anak usia 5-6 tahun berdasarkan Standar Pendidikan Nasional Pendidikan Anak Usia Dini (PAUD) dan melakukan deteksi dini terhadap hambatan pencapaian perkembangannya. Penelitian ini merupakan penelitian kualitiatif jenis deskriptif dengan subjek penelitian dua anak yang berusia 5 tahun dan usia 6 tahun. Data dikumpulkan menggunakan observasi, wawancara dan beberapa rangkaian stimulus untuk mendukung munculnya respon pencapaian perkembangan yang hendak diukur mulai aspek nilai agama-moral, fisik-motorik, kognitif, bahasa, sosial-emosional, sampai pada aspek seni. Data yang sudah terkumpul dianalisis menggunakan analisis deskriptif. Hasil penelitian menunjukkan bahwa dari kedua subjek masih ada beberapa indikator pencapaian yang belum dan lebih banyak yang sudah tercapai dari semua aspek perkembangan anak usia dini. Keberhasilan dari pencapaian standar tingkat pencapaian perkembangan anak usia dini dapat disebabkan oleh pola asuh yang diberikan oleh orangtua kepada anak, pemberian stimulasi yang sesuai dengan tingkat usia dan perkembangan anak serta faktor-faktor pendukung yang bersumber dari lingkungan sekitar anak.
CAPAIAN DAN STIMULASI ASPEK PERKEMBANGAN AGAMA PADA ANAK USIA 5 TAHUN
Authors: T M. Yusuf , Safitri Eka Diah , Masnah Siti , Ibadiyah Bahriatul
Published: September 2020

Penelitian ini bertujuan untuk menggambarkan perkembangan agama anak pada usia 5 tahun berdasarkan standar tingkat perkembangannya serta merumuskan stimulasi yang tepat untuk memaksimalkan perkembangan itu berdasarkan teori perkembangan anak. Penelitian dilakukan   menggunakan   pendekatan   kualitatif   deskriptif   dengan   teknik   pengamatan terstruktur terhadap tiga orang anak yang dipilih berdasarkan kriteria, yaitu: (1) berusia 5 tahun; (2) bersedia menjadi subjek penelitian; (3) dapat dijangkau secara fisik. Dengan menggunakan teknik observasi dan wawancara, instrumen disiapkan mengikuti rumusan Standar Tingkat Pencapaian Perkembangan Anak (STPPA) PAUD dan dianalisis secara deskriptif-naratif. Hasilnya menunjukan bahwa berdasarkan STPPA, anak telah memenuhi capaian  perkembangan  pada  aspek  agama  pada  indikator:  (1)  mengenal  agama  yang dianutnya; (2) mengerjakan ibadah sederhana yang menjadi ajaran agama yang dianutnya; (3) mengetahui hari besar agamanya; dan (4) menghormati agama orang lain. Berdasarkan hasil penelitian pula ditemukan beberapa stimulasi yang dapat meningkatkan capaian aspek perkembangan agama pada anak usia 5 tahun, yaitu: (1) mendongeng di depan anak tentang kisah tokoh agama; (2) mengingatkan anak  untuk melakukan ibadah;  (3) memberi  anak contoh perbuatan yang baik; (4) memberi anak reward jika anak berperilaku positif.
ELEMENTS OF OPEN PUBLIC SPACE AT CORRIDOR SOMBAOPU STREET MAKASSAR CITY
Authors: Ersina Sriany
Published: September 2020

Physical elements forming characters in the corridor Somba Opu street Makassar city such as trees/shade, diversity of buildings, street furniture, open space, accessibility, density, contrast, parking, pedestrian pathways, and pavement are still considered to be less supportive of characteristics and strengthen the identity of the corridor area the street. In this case, the physical elements still give the impression of being neglected on several corridor Somba Opu street Makassar city, besides that improper arrangement and processing of elements can also affect the convenience of visitors in shopping or users of the corridor Somba Opu street Makassar city, giving rise to responses from community groups to the physical elements in the corridor. From this background, the formulation of the problem in this study is the extent of the influence of the physical elements forming the character of the corridor Somba Opu street Makassar city, and which physical elements dominate the character formation of the corridor Somba Opu street Makassar city, according to the community response. This paper is intended to analyze and find out the physical elements that dominate the character formation of the street corridor that automatically affects the characteristics that already exist on the corridor Somba Opu Street Makassar city based on the response from the community. In this study, it is based on a quantitative and qualitative paradigm, which will compare the response of the community to the physical elements forming the street character. The method in this study was through questionnaires and interviews with community groups (shop owners, street users/visitors, and street vendors) to find out their responses to the physical elements that make up the character in the corridor Somba Opu Street Makassar city, and then obtain the data analyzed with the help of the SPSS program with discriminant techniques. The results of this study indicate the element of accessibility that dominate the formation of the corridor Somba Opu street Makassar city corridor character, according to the response from the community (shop owners, users/visitors, and street vendors).
A Emergência Médica e a Medicina Paliativa: A Necessidade de uma Agenda Comum
Authors: Pereira Bernardo , Reis-Pina Paulo
Published: September 2020

O campo de acção da emergência médica acarreta um risco inerente de inadequação de cuidados aos doentes com necessidades paliativas. A relevância do tema impõe uma reflexão assertiva que visa, em última instância, a sua inclusão mandatória na agenda dos diferentes órgãos de formação médica.
COVID-19 e Doença Cardiovascular: Consequências Diretas e Linhas de Investigação
Authors: Mamade Yasmin , Mendes Inês , Balhana Sílvia , Pereira Carla Sofia , Vasoncelos Mafalda , Moreira Ana Patrícia , Araújo Francisco
Published: September 2020

A infeção por SARS-CoV-2 não deixou ninguém incólume ou indiferente. Trouxe implicações profundas na vida diária e na saúde individual, mas também a nível económico e social. A nível da doença cardiovascular, a repercussão da COVID-19 foi enorme. Muito há ainda por saber e a informação é muitas vezes contraditória. Este artigo pretende apontar linhas de investigação que poderão ser úteis para encontrar respostas na relação entre a infeção a SARSCoV- 2 e a doença cardiovascular. Exploramos aquilo que se sabe sobre os efeitos diretos da doença, abordando os mecanismos fisiopatológicos, quer sejam a agressão celular direta, a tempestade inflamatória, a angiopatia trombótica, a hipóxia ou a disfunção de lipoproteínas.
Profesionalisme Dakwah Dalam Pemberdayaan Masyarakat
Authors: Hendra Tomi
Published: September 2020

Da'wah is a very noble activity, where a missionary interpreter seeks to convey the message of truth to the community, with the aim of inviting the community to be able to become better in life. The missionary activities are not only limited to the delivery of religious messages, but the activities of the missionary interpreter must be realized in the form of professionalism in preaching. Da'wah is not only concerned with the interests of the group but the common interest, from this point of view the professionalism of the missionary interpreter is highly demanded, so that it does not harm other parties as the target. In the community the missionary interpreter is not limited to conveying religious messages to the community at large, but a missionary interpreter must be able to play a role in community empowerment. By playing a role as an agent of empowerment, it will increasingly appear professionalism for a missionary interpreter. This paper is to find out how professional propaganda in community empowerment. A missionary interpreter has two important roles in community life; First, as a messenger of religious messages, secondly, as agents of empowerment for the community, so that with these two important roles Islam can be integrated into community empowerment by mixing all dimensions of people's lives in it.Keywords: Da'wah Professionalism in Community Empowerment.  Abstrak             Dakwah merupakan aktifitas yang  sangat mulia, dimana seorang juru dakwah berupaya menyampaikan risalah kebenaran kepada masyarakat, dengan tujuan mengajak masyarakat mampu menjadi yang lebih baik lagi dalam kehidupan. Aktifitas juru dakwah tidak hanya sebatas dari penyampai pesan-pesan agama, tetapi aktifitas juru dakwah ini harus diwujudkan dalam bentuk profesionalisme dalam berdakwah. Berdakwah tidak hanya mementingkan kepentingan golongan tetapi kepentingan bersama, dari sudut pandang inilah profesionalisme juru dakwah sangat dituntut, sehingga tidak merugikan pihak lain apa lagi masyarakat sebagai sasarannya. Dalam lingkungan masyarakat juru dakwah bukan sebatas dari menyampaikan pesan-pesan agama kepada masyarakat secara luas, tetapi seorang juru dakwah harus mampu berperan dalam pemberdayaan masyarakat. Dengan memainkan peran sebagai agen pemberdayaan, maka akan semakin tampak profesionalime seorang juru dakwah. Tulisan ini untuk mengetahui bagaimana propfesional dakwah dalam melakukan pemberdayaan masyarakat. Seorang juru dakwah memiliki dua peran penting dalam kehidupan bermasyarakat; Pertama, sebagai penyampai pesan-pesan agama, kedua, sebagai agen pemberdayaan bagi masyarakat, Sehingga dengan dua peran penting ini Islam bisa teintegrasi dalam pemberdayaan masyarakat dengan bercampur segala dimensi kehidupan masyarakat di dalamnya.Kata kunci: Profesionalisme Dakwah Dalam Pemberdayaan Masyarakat.
MASYARAKAT MADANI ANTARA SEMU DAN REALITA
Authors: Hasibuan Armyn
Published: September 2020

This paper discusses the civil society be the goal of missionary activity in the present and future. This paper uses a literature review of books about the themes in the study . After a study found that the civil society to achieve the necessary awareness, willingness , readiness , unity and national partnership patriotic , religious , selfless solidarity or socialism . It is something that is difficult to reach, so, it’s between  realty and impossible but the first step has been started by the Prophet as a personal leader and manager.This is had ever exsist to example.Tulisan ini membahas tentang masyarakat madani yang menjadi tujuan dalam kegiatan dakwah pada masa sekarang dan akan datang. Tulisan ini menggunakan kajian literatur dari buku-buku yang berkenaan dengan tema kajian. Setelah dilakukan kajian mendapatkan bahwa untuk mencapai masyarakat madani diperlukan kesadaran, kemauan, kesediaan, kebersamaan dan kemitraan kebangsaan yang patriotis, religious, solidaritas atau sosialisme tanpa pamrih. Memang sesuatu yang sukar dicapai sampai orang mengatakan masyarakat madani antara semu dan realita, namun langkah awal telah dimulai oleh Rasulullah Saw sebagai pribadi yang leader dan manager.Tentu sesuatu yang telah pernah ada menjadi percontohan yang dapat ditiru dan diambil.
Peranan Praktek Menjahit di Lembaga Kursus dan Pelatihan (LKP) Inun: Strategi Pemberdayaan Perempuan
Authors: Budi Harahap Aisyah
Published: September 2020

Inun Institute for Training and Training (LKP) is an institution under the auspices of the Binjai City Women's Empowerment Office authorized in the field of women's empowerment through a sewing skills program. The institution aims to create skilled workers in the field of sewing clothes. The institute educates trainees totaling 20 people consisting of housewives and women dropping out of school under experienced instructors. This training runs for 3 months. It is expected that after receiving training, participants will be able to be independent and be able to open their own jobs. This study aims to determine the role of LKP Inun in empowering women through sewing skills programs, as well as the economic impact after receiving training. The research method used is in the form of a qualitative study with literature. Data obtained from interviews, non-participant observation, and documentation.The results of the study found that trainees succeeded in increasing family income. It was evident from interviews that trainees could help with their children's education costs from the results of sewing wages.Lembaga Kursus dan Pelatihan (LKP)  Inun merupakan lembaga dibawah naungan Dinas Pemberdayaan Perempuan kota Binjai yang berwenang dibidang pemberdayaan perempuan melalui program keterampilan menjahit Lembaga yang bertujuan menciptakan tenaga terampil dibidang penjahitan pakaian  ini memberdayakan perempuan khususnya di kota Binjai agar mampu mandiri dalam bidang perekonomian. Lembaga  tersebut mendidik peserta latihan yang berjumlah 20 orang yang terdiri dari ibu rumah tangga dan wanita putus sekolah di bawah instruktur yang berpengalaman. Pelatihan ini berjalan selama 3 bulan. Diharapkan setelah mendapatkan pelatihan, peserta mampu mandiri dan bisa membuka lapangan pekerjaan sendiri. Penelitian ini bertujuan untuk mengetahui peran LKP Inun dalam memberdayakan perempuan melalui program keterampilan menjahit, serta  dampak  perekonomian setelah mendapatkan pelatihan. Metode penelitian yang dipakai berbentuk kualitatif dengan pendalaman pustaka. Data didapat dari wawancara, observasi non partisipan, serta dokumentasi. Hasil dari penelitian didapat bahwa peserta latihan berhasil meningkatkan pendapatan keluarga. Terbukti dari wawancara bahwa peserta latihan bisa membantu  biaya pendidikan anaknya dari hasil upah menjahit.Kata Kunci: Pemberdayaan, Perempuan
PERAN PEMERINTAH DAERAH DALAM MEMBERDAYAKAN MASYARAKAT UNTUK MENINGKATKAN PEMBANGUNAN DAERAH
Authors: Damanik Adlin
Published: September 2020

Pembangunan berdimensi jamak, meliputi aspek sosial, ekonomi, ekologi dan institusi. Keterbelakangan dan ketertinggalan yang terjadi pada suatu daerah merupakan kondisi objektif yang harus dipikirkan dalam setiap proses pembangunan. Bagaimanapun proses pembangunan menghasilkan konsekuensi. Upaya menanggulangi keterbelakangan masyarakat dapat dilakukan melalui usaha yang mendasar, yakni secara sektoral, segmental (bagian) dan spatial (lokasi/ruang/tempat). Paradigma pendekatan pemberdayaan masyarakat menjadi kata kunci untuk keluar dari problem keterbelakangan dalam konteks pembangunan daerah. Dalam proses pemberdayaan masyarakat, pemerintah daerah dituntut memformulasi konsep yang jelas dan terarah bagi arah pembangunan dan pengembangan daerah dengan beragam potensi yang dimilikinya untuk kemudian digunakan dan dimanfaatkan menuju kemakmuran dan kebahagiaan masyarakat di daerah secara nyata. Kata Kunci: Pemerintah Daerah dan Pemberdayaan Masyarakat
Media Massa Dalam Komunikasi Pembangunan
Authors: Hendra Tomi
Published: September 2020

Abstract: In the current era of technology, the development of society in social life isvery dependent on mass media, where mass media has a very important role in thismatter. One of the important roles of mass media for the community is as a provider ofinformation, education, and entertainment for the community so that in this way thecommunity is motivated, affected and strives to change the mindset and perspective inlife. In addition, the presence of mass media greatly helps the development process inthe lives of social communities. Along with technological advancements that are closelyrelated to mass media, it cannot be denied that the growth of people's lives will also bemore complete. With the development of mass media at this time the community is ableto respond and be smarter towards the reality around the effects of the growth of thedynamics of their lives.Keywords: Mass Media in Development communicationAbstrak: Di Era teknologi saat ini, perkembangan masyarakat dalam kehidupan sosialsangat tergantung akan media massa, dimana media massa sangat memiliki peran dalamhal tersebut. Salah satu peran penting media massa bagi masyarakat yaitu sebagaipemberi informasi, pendidikan, dan hiburan bagi masyarakat sehingga dengan haldemikian masyarakat termotivasi, terpengaruh dan berusaha untuk merubah pola pikirserta cara pandang dalam kehidupan. Selain itu kehadiran media massa sangatmembantu proses pembangunan dalam kehidupan masyarakat sosial. Seiring dengankemajuan teknologi yang erat hubungannya dengan media massa tidak dapat dipungkiribahwa pertumbuhan kehidupan masyarakat juga akan semakin lengkap. Denganperkembangan media massa saat ini masyarakat mampu merespon dan bisa lebih cerdasterhadap realitas yang ada di sekitar efek dari pertumbuhan dinamika kehidupannya.Kata kunci: Media Massa Dalam komunikasi Pembangunan
MENEROPONG MAKNA, WACANA DAN PENDEKATAN DAKWAH DALAM PEMBENTUKAN DAN PEMBERDAYAAN MASYARAKAT ISLAM
Authors: Ritonga Anas Habibi
Published: September 2020

Makna, wacana dan pendekatan dakwah merupakan hal yang sangat urgen untuk dikaji, karena sangat menentukan sukses atau tidaknya sebuah dakwah yang pada akhirnya akan membentuk dan dan mengikuti perkembangan masyarakat, dan disii lain masyarakat adalah mahluk yang dinamis, berubah sesuai dengan perkembangan jaman.Maka perlu dilakukan pemaknaan terkini bagaimana melakukan pembentukan dan perkembangan masyarakat Islam yang sesuai dengan konteks kekinian, dan wacana apa yang harus digulirkan untuk mendorong pembentukan dan perkembangan masyarakat Islam dan terakhir bagaimana pendekatan dakwah yang mesti dilakukan agar dakwah itu tidak monoton yang ditinggalkan umat.Pemberdayaan dapat diartikan sebagai upaya membangkitkan kesadaran akan potensi yang dimiliki serta berupaya untuk mengembangkannya sehingga masyarakat dapat mencapai kemandirian. Tulisan ini mencoba untuk melihat makna, wacana dan pendekatan dakwah dalam pembentukan dan pemberdayaan masyarakat Islam dan bagaimana pula fungsi pendekatan dakwah dalam pemberdayaan masyarakat Islam.
New Archaeological Discoveries in The Geological Formations and Heritages along the Ba River Ancient Valley
Authors: Phuc La The , Tuat Luong Thi , Thom Bui Van , Su Nguyen Khac , Duc Vu Tien , Anh Bui Quang , Minh Nguyen Trung , Hai Yen Dang Thi
Published: September 2020

In dry season of 2019, a series of new mix-heritages containing both of natural/geological and prehistoric archaeological values were discovered along the Ba river ancient valley by the field survey team of the project TN17/T06. The archaeological relics were uncovered right in the geological heritage sites such as: waterfalls, fossil sites, ancient terraces, and low mountain slopes along the Ba river ancient valley, which belong to eluvial, deluvial, proluvial and alluvial formations of Pleistocene age. Hundreds of stone tools, including dozens of petrified wood tools were collected, such as: uni-facial and bi-facial tools, end-chooper, side-chopper, scraper, spearhead tool, flake and core tools, etc. The materials of the tools were made of quartz, quartzite, siliceous stone, opal-chalcedony, petrified wood and basalt, which were recognized as geological heritages (A type: Paleontology; D type: Rock; F type: Minerals, according to the classification in the Circular 50/2017-TT-BTNMT of MONRE) of the heritage region. The collected artifacts characterise technique and geometric shape types of Paleolithic age. The archaeological discoveried sites were highly evaluated by Vietnamese and foreign archaeologists because they play a great important role in studying Paleolithic stage in Gia Lai province and The Central Highlands particularly, and in Vietnam and Southeast Asia generally. Besides, they have increased comprihensive heritage values of the region, as well as provided double invaluable resources (both natural and cultural heritage) for tourism exploitation and socio-economic sustainable development.
Application of Theoretical System in The Development of Policies on Evaluation Capacity for Science and Technology Information Organizations in Vietnam
Authors: Son Le Tung
Published: September 2020

Evaluation of operational capacity in science and technology information playing an important role in promoting innovation in scientific and technological information activities in Vietnam in order to meet the right of access to scientific and public information technology of organizations and individuals. Based on the application of theoretical system, the study proposes a policy to assess the operational capacity of science and technology information organizations with 02 basic measures: building a capacity assessment framework and evaluation methods. Therefore, the study recommends the promulgation and implementation of this policy.
The Solution to Overcome Conflicts in the Protection of Trademarks and Trade Names
Authors: Thi Thanh Dang , Quang Nguyen Nhat
Published: September 2020

Abstract: The objective of this paper is to propose solutions to overcome conflicts between industrial property rights over trademarks and industrial property rights over trade names. The research tasks consist of: Identifying the cause and the nature of the conflict, the mechanism to deal with the conflict under Vietnam current law; Pointing out unresolved issues in that mechanism, comparing with intellectual property law and practice of other countries to look for proper solutions for Vietnam.
The Impacts of Facebook on Students Today: Status-quo and Policy Recommendations
Authors: Lan Nguyen Nguyen
Published: September 2020

With the rapid development of online platforms today, social networking sites, especially Facebook, are having strong impacts on all aspects of student life. This article focuses on analyzing the impacts of Facebook on students in terms of these following main aspects: learning; skills development; attitude training. At the same time, the article also presents a number of policy recommendations to improve the efficiency of managing the impacts of Facebook as a social networking site on Vietnamese students in the coming time.
Determination of Amphetamine and Methamphetamine in Human Hair by Gas Chromatography Mass Spectrometry
Authors: Quoc Chinh Pham , Thi Thu Ha Pham , Mai Dung Nguyen , Huu Phuoc Vu , Duc Loi Vu , Tien Vung Nguyen
Published: September 2020

This article develops a combined solid phase extraction (SPE) and gas chromatography – mass spectrometry (GC-MS) procedure for determining amphetamine-type stimulants Amphetamine (AM) and Methamphetamine (MA) in human hair. Hair samples were incubated in methanol containing 1% hydrochloric acid in 18 hours and then subjected to SPE. The obtained extracts were evaporated to dryness, derivatized with heptafluorobutyric anhydride (HFBA) at 70 °C for 30 minutes prior to GC–MS analysis. Gas chromatography mass spectrometry was run on HP5-MS column (30 m × 0.25 mm × 0.25 µm) with detector MS 5975C. Experimentally, the proposed method proved sensitive, simple and time-saving, but quite accurate with a low limit of detection (LOD = 0.05ng/mg) and quantitation (LOQ = 0.15ng/mg).

Keywords:

SPE, GC – MS, hair samples, amphetamine, methamphetamine.

References

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Benefício do uso de inibidores do co-transportador renal de sódio-glicose 2 (iSGLT- 2) em pacientes com Diabetes Mellitus 2 e Insuficiência Cardíaca
Authors: Rodrigues Laryssa de Lacerda , Pacheco Celestino Isadora Thamires , Fortunato Santos Fabiano , De Souza Oliveira Gabriel , Reveileau Magagnin Gabriel , Viterbo Laia Guilherme Francisco , Almeida Ferreira Luíza , Cunha Corgosinho Maike , Abreu Nunes Mariana , Rodrigues de Paula Gomes Pedro Victor
Published: September 2020

Objetivo: Realizar uma revisão sistemática da literatura abordando como os Inibidores do co-transportador renal de sódio-glicose 2 (iSGLT2) atuam nos sistemas cardiovascular e renal e quais são os seus benefícios para pacientes portadores de Diabetes Mellitus Tipo 2 (DM2) e Insuficiência Cardíaca (IC). Métodos: Trata-se de uma revisão de literatura realizada com artigos da base de dados Medline® contida na plataforma Pubmed®. Foram encontrados 248 artigos, sendo 32 selecionados para análise preliminar através dos filtros “Full Text”; “Clinical Trial” e “Randomized Controlled Trial”. Após leitura na íntegra, 8 estudos foram selecionados para análise e discussão dos seus resultados. Resultados: Dentre os estudos, todos demonstraram redução em internação ou morte por IC e 7 demonstraram tais benefícios associados a outras doenças cardiovasculares em pacientes em uso de iSGLT2. Considerações finais: Os iSGLT2 apresentam benefícios para portadores de IC e DM2, como diminuição da glicemia, dos níveis de HbA1c, do peso e da pré-carga, resultando em redução de internação ou morte por IC e outras doenças cardiovasculares.
Treatment of bilateral punctal stenosis and nasolacrimal duct obstruction in an 11-year-old case with dyskeratosis congenita
Authors: Eroglu Fatma Corak , Sen Emine , Ellik Suleyman
Published: September 2020

The purpose of this study was to report the external dacryocystorhinostomy (ext-DCR) using silicone intubation in a child with dyskeratosis congenita (DC) who had presented by bilaterally acquired nasolacrimal duct obstruction (NLDO), punctal stenosis, and mucocutaneous changes. We report the 13-month results of an 11-year-old boy with DC who underwent bilateral ext-DCR with silicone stenting under general anesthesia. Ophthalmic examination revealed bilateral punctal stenosis and NLDO with normal fundus examination. He was referred to pediatrics and was diagnosed as DC, based on classic reticular skin pigmentation, nail dystrophy, and oral leukoplakia, without any other systemic involvement. Treatment consisted of bilateral ext-DCR using silicone stenting by 6 months. Management of surgery and post-operative 13-month follow up results was observed. DC is a rare heterogeneous multisystem disorder of telomere maintenance, which may present with ophthalmologic features. Although the lacrimal system abnormalities have been reported most frequently ocular findings in DC, this is the first case to present the management and long-term results of DCR using silicone intubation. This case aims to raise awareness of the various systemic and ocular manifestations and possible complications of DC and to present long-term results of ext-DC in a patient with DC.
Genetic characterization of a case of sellar metastasis from bronchial carcinoid neuroendocrine tumor
Authors: Christopher S . Hong , Kundishora Adam J. , Elsamadicy Aladine A. , Koo Andrew B. , Beckta Jason M. , McGuone Declan , Erson-Omay E. Zeynep , Omay Sacit Bulent
Published: September 2020

Background:

Metastasis to the pituitary gland from neuroendocrine tumors is a rare occurrence that may originate from primary tumors the lung, gastrointestinal tract, thyroid, and pancreas, among others. Patients may present with signs of endocrine dysfunction secondary to pituitary involvement, as well as mass effect-related symptoms including headaches and visual deficits. Despite a small but accumulating body of literature describing the clinical and histopathological correlates for pituitary metastases from neuroendocrine tumors, the genetic basis underlying this presentation remains poorly characterized.

Case Description:

We report the case of a 68-year-old with a history of lung carcinoid tumor who developed a suprasellar lesion, causing mild visual deficits but otherwise without clinical or biochemical endocrine abnormalities. She underwent endoscopic endonasal resection of her tumor with final pathology confirming metastasis from her original neuroendocrine tumor. Whole-exome sequencing was performed on the resected sellar tumor and matching blood, revealing increased genomic instability and key mutations in PTCH1 and BCOR that have been previously implicated in both systemic neuroendocrine and primary pituitary tumors with potentially actionable therapeutic targets.

Conclusion:

This is the first genomic characterization of a metastatic tumor to the sella and reports potential genetic insight, implicating PTCH1 and BCOR mutations, into the pathophysiology of sellar metastasis from primary systemic tumors.
Relationship of superior sagittal sinus with sagittal midline: A surgical application
Authors: Oberman Dan Zimelewicz , Rabelo Nícollas Nunes , Correa Jorge Luiz Amorim , Ajler Pablo
Published: September 2020

Background:

Interhemispheric approach is widely used to surgical management of midline tumors and vascular lesion in and around the third ventricle. Complete exposure of the superior sagittal sinus to obtain adequate working space of midline lesion is difficult, because of the risk to inadvertent injury to the sinus and bridging veins, which may cause several neurological deficits. Understanding the SSS neuroanatomy and its relationships with external surgical landmarks avoid such complications. The objective of this study is to accurately describe the position of SSS and its displacement in relation with sagittal midline by magnetic resonance imaging.

Methods:

A retrospective cross-sectional, observational study was performed. Magnetic resonance image of 76 adult patients with no pathological imaging was analyzed. The position of the halfway between nasion and bregma, bregma, halfway between bregma and lambda, and lambda was performed. The width and the displacement of the superior sagittal sinus accordingly to the sagittal midline were assessed in those landmarks.

Results:

The mean width of superior sagittal sinus at halfway between nasion and bregma, bregma, halfway between bregma and lambda, and lambda was 5.62 ± 2.5, 6.5 ± 2.8, 7.4 ± 3.2, and 8.5 ± 2.1 mm, respectively, without gender discrepancy. The mean displacement according to the midline at those landmarks showed a statistically significant difference to the right side among sexes.

Conclusion:

In this study, we demonstrate that sagittal midline may approximate external location of the superior sagittal sinus. Our data showed that in the majority of the cases, the superior sagittal sinus is displaced to the right side of sagittal midline as far as 16.3 mm. The data we obtained provide useful information that suggest that neurosurgeons should use safety margin to perform burr holes and drillings at the sagittal midline.
Case Report (Precis): Patient with MR-Documented Large Lateral Cervical Disc Misdiagnosed as Neurodegenerative Disease
Authors: Epstein Nancy E.
Published: September 2020

Background:

Patients who present to neurologists with cervical radiculopathy typically undergo initial MR scans. If reports show “abnormal” findings they, and other physicians, should review the studies with the interpreting radiologists/neuroradiologists. When patients’ neurological deficits progress, neurologists should review their electromyographic (EMG) findings (i.e. especially if documenting neurodegenerative disease), the initial “abnormal” MR scans/reports (i.e. review with radiologists/neuroradiologists), and obtain spinal surgical consultations to rule out “surgical” disease.

Case Description:

A middle aged patient presented several months previously to a neurologist with the chief complaint of unilateral neck/arm pain, accompanied by focal weakness, and numbness in a specific distal cervical nerve root distribution. The patient’s initial MR showed a large lateral disc herniation in the lower cervical spine on the symptomatic side. However, as the neurologist interpreted the EMG as consistent with a neurodegenerative syndrome, the patient was not referred to a spine specialist. Frustrated by progressive worsening, the patient ultimately referred himself for a spinal surgical consultation. By this time, he had developed severe unilateral upper extremity motor weakness (3/5), pin loss, atrophy, and fasciculations in the nerve root distribution that correlated with the location of the distal cervical disc seen on the original MR. When the repeat MR confirmed the same large distal lateral disc herniation, the patient successfully underwent an anterior cervical discectomy/fusion (ACDF).

Conclusion:

This Case Report (Precis) highlights two “teachable moments”. First, physicians, including neurologists and spinal surgeons, who order MR studies that show “abnormal” findings should review these studies with the interpreting radiologists/neuroradiologists. This is particuarly true if patients continue to demonstrate progressive neurological deterioration. Second, before patients are told that they have neurodegenerative syndormes, repeated review of the MR reports and/or repeating these studies, and obtaining spinal surgical consultations are warranted to rule out “surgical” disease.
CYCLIC SYSTEM FOR TRAINING SPECIALISTS OF ECONOMIC SECURITY OF ENTERPRISES AND ORGANIZATIONS
Authors: Vlasenko M. N. , Kunbutayev L. M. , Potekhetsky S. V.
Published: September 2020

It has been proved that the introduction of a cyclic system of professional training of specialists in economic security of enterprises and organizations contributes to increasing the efficiency of their functioning, competitiveness, financial and economic stability in the conditions of market uncertainty. It has been established that the introduction of cyclic methods of the systematic development of professional competencies of specialists of economic security must be implemented based on the results of the preliminary assessment of the internal and external environment of the enterprise, the main threats and risks posed by them. The main stages of organizing and conducting cyclical professional training have been developed, the factors contributing to the adaptation of the training system to the specifics of the enterprise have been identified, the content, essence, procedure for conducting educational and methodological activities have been described. The main restrictions and priorities in the organization and conduct of educational and methodological activities aimed at ensuring the required level of economic security of production facilities have been ascertained. The list of current and prospective tasks that need to be solved during the implementation of training activities has been defined.
SOCIAL DEVELOPMENT OF PERSONNEL IN THE CONDITIONS OF INNOVATIVE ECONOMY AS A FACTOR OF INCREASING THE LEVEL OF LIFE QUALITY
Authors: Laas N. I. , Romanova I. A. , Gurova E. V.
Published: September 2020

The importance of the social development of personnel in innovative economy as a decisive factor in the stability of society and improving the quality of life of both workers themselves and the entire population of the country has been defined. It has been shown that social development of staff in the organization contributes to the improvement of social and labor relations through interaction of the parties of social partnership based on the principle of tripartite cooperation and “tripartism”, and also contributes to the full development of the potential of employees and their professional competences. The main directions of social development of personnel included in the social policy of the organization have been determined in the paper. As a result of the research, priority role of cash payments and guarantees in the organization’s social responsibility strategy have been identified. At the same time, the main principle in the development of policy aimed at social development of staff should be targeted consideration of the needs of employees. The principle of targeting to determine the level of staff satisfaction should be the main one for evaluating the effectiveness of work in this direction. In addition, the authors point to the need to use modeling and forecasting the prospects of social innovations in order to achieve sustainable development in the long term.
BUSINESS DECISION TRENDS IN THE INTELLECTUAL PRODUCTION DEVELOPMENT
Authors: Shinkevich A. I. , Kudryavtseva S. S. , Shinkevich M. V.
Published: September 2020

The main trends have been described and the system characteristics of intellectual production have been presented: customization of products, integration of the product and the service it provides, the transition to integrated solutions and services, mass personification while reducing the share of costs per unit of output and customer waiting time for an order. The key components of the transformation of business management models in the fourth industrial revolution have been identified. Cross-correlation and regression analysis for indicators of high-tech production have been made. A basic, optimistic and pessimistic forecast of changes in the share of high-tech and technology products in the gross domestic product, depending on the growth of high-performance jobs, has been built. The analysis of the development of intellectual production presented in the article, as well as the results of modeling can be used in the construction of forecast trends of the economy in the transition to the fourth industrial revolution.
CURRENT TRENDS OF ATTRACTING YOUNG PROFESSIONALS TO ORGANIZATIONS
Authors: Suvalov O. S. , Suvalova T. V.
Published: September 2020

The purpose of the study is to analyse the system of attracting young professionals to the modern companies in order to reveal their potential. The relevance has been substantiated and the advantages of this area have been noted in the article. The ability of young people to learn quickly, their high adaptability to changes, readiness for additional loads and business trips, flexibility and mobility have been noticed. The importance of building the system “school – university – organization” has been considered. The main options for recruiting young specialists have been highlighted: selection for initial positions, for trainee positions, programs for selecting the best candidates. The most important motivating factors for young professionals when choosing an employer and future field of activity have been identified. The increasing role of professional growth opportunities, the importance of professional development and the possibilities to realize their potential, the availability of a social package and a convenient work schedule have been noted.
Description of Two-particle One-hole Electronic Resonances using Orbital Stabilization Methods
Authors: Thodika Mushir , Mackouse Nathan , Matsika Spiridoula
Published: September 2020

Two-particle one-hole (2p-1h) resonances are elusive to accurate characterization, their decay to the neutral state being a two-electron process.

Although in limited cases single reference methods can be used, a proper description of a 2p-1h resonant state entails a multi-configurational treatment of the reference wavefunction. In this work we test the performance of the orbital stabilization method to characterize the 2p-1h resonances found in water and benzene. We employ a set of two multi-reference approaches, namely the restricted active space self-consistent field and multi-reference configuration interaction, as well as, the single reference method, equation of motion for electron attachment coupled-cluster with singles and doubles, in the case of benzene.

We further explore the resonant channel mixing in benzene between the B2g shape resonance and 2p-1h resonance, a phenomenon which has been mentioned quite often in experimental studies.
Ordered LiNi0.5Mn1.5O4 Cathode in Bis(fluorosulfonyl)imide-Based Ionic Liquid Electrolyte: Importance of the Cathode-Electrolyte Interphase
Authors: Lee Hyeon Jeong , Brown Zachary , Zhao Ying , Fawdon Jack , Song Weixin , Lee Ji Hoon , Pasta Mauro
Published: September 2020

The high voltage (4.7 V vs. Li+ /Li) spinel lithium nickel manganese oxide (LiNi0.5 Mn1.5 O4 , LNMO) is a promising candidate for the next-generation of lithium ion batteries due to its high energy density, low cost and environmental impact. However, poor cycling performance at high cutoff potentials limits its commercialization. Herein, hollow structured LNMO is synergistically paired with an ionic liquid electrolyte, 1M lithium bis(fluorosulfonyl)imide (LiFSI) in N-propyl-N-methylpyrrolidinium bis(fluorosulfonyl)imide (Pyr1,3 FSI) to achieve stable cycling performance and improved rate capability. The optimized cathode-electrolyte system exhibits extended cycling performance (>85% capacity retention after 300 cycles) and high rate performance (106.2mAhg–1 at 5C) even at an elevated temperature of 65 ◦C. X-ray photoelectron spectroscopy and spatially resolved x-ray fluorescence analyses confirm the formation of a robust, LiF-rich cathode electrolyte interphase. This study presents a comprehensive design strategy to improve the electrochemical performance of high-voltage cathode materials.
ANÁLISIS DE LAS CURVAS DE INFILTRACIÓN PARA DETERMINAR CAUDALES MÁXIMOS EN ZONAS DE ESCASA INFORMACIÓN ANTE EVENTOS EXTREMOS
Authors: Arriola Carrasco Guillermo Gustavo , Villegas Granados Luis Mariano , Sotomayor Nunura Gioconda Del Socorro
Published: September 2020

La presente investigación tiene como fin la determinación de los caudales máximosen las zonasalejadas de unacuenca donde no se cuenta con información pluviométrica ni hidrométricaempleando el análisis de las curvasde infiltración considerando como primer dato de entrada el método del número de curva. La metodología quese empleó consideró todos los valores de infiltración obtenidos en ciertas partes de la cuenca a partir delmuestreo de campo de los diversos tipos de suelos y de los pocos registros históricos de las estacionespluviométricas llamadas así como subcuencas para el análisis hidrológico y luego se aplicó el procesamiento deimágenes con la ayuda del programa NewLoc Clim v. 1.10 cuyos resultados nos permitieron identificar todoslos lugares vulnerables ante fuertes crecidas.
Informação adequada, confiável e oportuna em tempos de pandemia de COVID-19
Authors: Coutinho Janine Giuberti , Padilla Monica
Published: September 2020

Em tempos de pandemia da COVID-19, informação adequada, confiável e oportuna, torna-se mais ainda relevante. O escritório da Organização Pan-Americana da Saúde/Organização Mundial da Saúde no Brasil e parceiros, vêm desenvolvendo iniciativas para favorecer o acesso, compartilhamento e difusão das informações e conhecimentos produzidos, traduzidos, sistematizados sobre a COVID-19 como uma contribuição técnica para o enfrentamento da pandemia. Este artigo apresenta alguns desses recursos. É fundamental considerar como máxima relevância a produção e sínteses de conhecimento disponibilizado oportunamente para quem está na primeira linha de resposta à COVID-19. Isto como requisito básico para melhorar a capacidade de resposta. É importante também o fortalecimento e incremento nos investimentos para produção de ciência e evidência, e o reconhecimento e fortalecimento do incansável trabalho de um enorme contingente de cientistas e instituições que continuam imbuídas a responder à pandemia da COVID-19.
Syariat Islam dan Hukum Negara : Sebuah Kontemplasi
Authors: Aksin Nur
Published: September 2020

Syariah, apabila dikaitkan dengan kehidupan sehari-hari seperti halnya kehidupan dan tatanan sosial, maka sebenarnya, kedua hal ini tidaklah saling bertentangan, dengan kata lain keduanya tersebut saling melengkapi satu sama lain, dan dapat dikatakan pula bahwa, syariah tersebutlah yang menciptakan keteraturan dalam berkehidupan sosial. Oleh karenanya, patutlah bagi kita untuk mengetahui dan menelaah lebih lanjut terkait apa yang ada dalam sebuah hukum Islam (syariah) dalam hubungannya dengan hukum tettulis yang merupakan hukum yang dibuat oleh negara..

Penelitian menggunakan metode yuridis normatif yang bertumpu pada literatur dan bersifat kualitatif. Hasil penelitian menunjukkan bahwa Hukum tertulis Indonesia sudah mendidik seseorang, menegakkan keadilan dan mewujudkan kemaslahatan bagi manusia sebagaimana komponen pembentuk rahmah yang menjadi dasar bagi syariat islam Sebagai umat yang tinggal saling berdampingan dengan umat lainnya, maka alangkah baiknya apabila kita lebih mengedepankan apa yang sepatutnya dapat menjaga sebuah kemajemukan yang merupakan sunatullah tersebut tidaklah menjadi sesuatu yang nantinya akan hilang dan rusak.