bluuebunny/crossref_metadata_2025 huggingface dataset:
О некоторых новых теоремах в классах типа Неванлинны в единичном круге
Authors: Shamoyan R. , Mihi´c O.
Published: April 2023

The study of various infinite products in various spaces of analytic functions in the unit disk is a well known and well studied problem of complex function theory in the unit disk. The goal of our paper is to study so-called Blashcke type products in new large, general analytic area Nevanlinna spaces in the unit disk.A new approach is suggested in this paper, namely we prove, use and apply various new embedding theorems which relate new general, large analytic area Nevanlinna spaces with less general well-studied and wellknown such type analytic spaces in the unit disk. Our theorems can be applied or can be used even in more general situation, when we consider large, general analytic area Nevanlinna spaces not in the unit disk, but in the circular ring.In our paper, using same approach new parametric representations of mentioned large, general analytic area Nevanlinna spaces are presented. These results also can be applied or used in the future to obtain more general theorems on parametric representations of mentioned large,general area Nevanlinna type spaces not in the unit disk, but in more general circular domains.

Общая задача о принадлежности тех или иных бесконечных произведений тем или иным аналитическим классам функций хорошо известна в литературе. Цель исследования, в частности, рассмотреть и изучить вопрос о принадлежности бесконечных произведений типа Бляшке к общим новым широким классам типа Неванлинны в единичном круге. Авторы для этого применяют новый метод, а именно доказываются и приводятся в статье различные новые теоремы вложения,связывающие новые общие классы типа Неванлинны с уже хорошо изученными и известными менее общими классами типа Неванлинны в единичном круге. Результаты статьи могут быть обобщены или использованы в более общем случае, когда рассматриваются общие, широкие классы Неванлинны в круговом кольце. В статье тем же методом также получены новые параметрические представления указанных широких классов типа Неванлинны в единичном круге. Вывод: эти результаты также могут быть использованы для получения новых параметрических представлений общих классов типа Неванлинны в круговом кольце.
Primary PPH What Worsen Maternal Outcome?
Authors:   Department of Obstetrics and Gynecology, Minia University, Egypt, R El Khateeb , M Kamal ,   Department of Obstetrics and Gynecology, Minia University, Egypt
Published: April 2023

Objective: The aim of the study was to explore factors that worsen maternal outcome (maternal morbidity and mortality) in cases developed Primary Postpartum Hemorrhage (PPH). Methodology: Cross sectional observational study carried out during the period from July 2016 till June 2017, 387 cases were recruited in the study from those who developed 1ry PPH. All data concerning cases were recorded including personal, obstetric, medical history, details of medical services received, complications and maternal mortality. Analysis of data recorded was done to determine factors associated with worse maternal outcome (morbidity and mortality). Results: 387 cases developed 1ry PPH (either managed in or referred) to hospitals of Minia Governorate (two secondary hospitals and one tertiary hospital) during the period of the study. 87 cases were excluded due to incomplete records. 1y PPH was common in MG 53% , residents’ rural areas 63.7%, patients not booked for ANC 59.7% and anemic patients 67.9%. Bivariate correlation of factors that worsen maternal outcome showed positive correlation between maternal complications and maternal age, parity, residence (rural areas), distance between residence and hospital (far), positive history of medical problems (anemia), blood transfusion and number of blood units. Maternal complications developed in 13.3%, coagulopathy was the most common 37.5%. 9 cases developed maternal mortality (3%) most common cause of death was irreversible shock 44.4%. Conclusion: Factors that worsen the maternal outcome in patients who developed primary PPH are residence in rural areas, decrease awareness of ANC importance, high parity, advanced maternal age, prevalence of anemia and decrease number of well qualified hospitals.
Evidence of Immunological Abnormalities in Sitosterolemia
Authors:   Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal and Child Sciences - DiNOGMI, University of Genova, Genoa, Italy, A La Rosa , A Ivaldi ,   Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal and Child Sciences - DiNOGMI, University of Genova, Genoa, Italy, F Penco ,   UOSD Center for Autoinflammatory Diseases and Immunodeficiencies, IRCCS Istituto Giannina Gaslini, Genoa, Italy, P Bocca ,   UOSD Center for Autoinflammatory Diseases and Immunodeficiencies, IRCCS Istituto Giannina Gaslini, Genoa, Italy, S Volpi ,   Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal and Child Sciences - DiNOGMI, University of Genova, Genoa, Italy, M Di Rocco ,   Department of Pediatric Sciences, Rare Diseases Unit, IRCCS Giannina Gaslini, Genoa, Italy
Published: April 2023

Objectives: Mutations involving the ABCG8 gene cause sitosterolemia (STSL), a rare metabolic disease due to an abnormal plasmatic plant sterols level. STSL hematological findings include stomatocytic hemolysis and macrothrombocytopenia. So far, few cases of leukopenia have been reported and there are no studies that consider inflammatory activity. The purpose of our study is to evaluate immunological abnormalities in STSL and the effect of dietary and pharmacological treatment. Study Design: In a sitosterolemic patient presenting leukopenia and increased inflammatory indexes were evaluated in vitro interleukin 1B secretion from monocytes and type 1 interferon (IFN) signature. Besides, Stimulation Indexes (SI) of patient’s and two Healthy Controls’ (HCs) T-helper lymphocytes in response to proliferative stimuli were assessed, when incubated in enriched medium alternately with patient plasma or with AB Rh+ group control plasma. SI (compared to the same HCs) and IFN signature have been evaluated again three (T3) and six (T6) months apart, after patient received therapy. Results: Following treatment with Ezetimibe (EZE) and adequate diet, lower plasmatic plant sterols levels and progressive improvement of hematological and immunological abnormalities were observed. These data were confirmed by the negativization of IFN signature at T3 and by the progressive normalization at T3 and T6 of SI in patient’s and HCs’ T-helper lymphocytes incubated in patient’s plasma-enriched medium. Conclusion: High plasmatic phytosterols levels due to STSL seems to affect white blood cells proliferation and trigger pro-inflammatory process, justifying leukopenia and increased phlogosis indexes observed in our patient. These hypotheses are supported by normalization of clinical and laboratory data during EZE therapy. Take-home Message: Immunological abnormalities should be considered among the hematological manifestations of sitosterolemia, moreover high levels of plasma phytosterols could be a pro-inflammatory trigger. Treatment with ezetimibe seems to reverse these manifestations.
TEK C2545T Germline Mutation in Blue Rubber Bleb Nevus Syndrome
Authors:   Department of Dermatology and Venereology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang, PR China, X Wu , L Chen ,   Department of Dermatology and Venereology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang, PR China, Y Xiao ,   Department of Dermatology and Venereology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang, PR China, Y Song ,   Department of Dermatology and Venereology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang, PR China, H Cheng ,   Department of Dermatology and Venereology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang, PR China
Published: April 2023

Objective: Blue rubber bleb nevus (BRBNS) syndrome is characterized by numerous venous malformations, which usually affect the skin, mucous, and gastrointestinal tract. However, the mechanisms of BRBNS syndrome are unclear. Materials and Methods: Blood samples were obtained from the fivegeneration pedigree and Genomic DNA was extracted from blood samples with a TianGen DNA Extraction Kit. Agilent SureSelect Exon sequencing was applied to capture suspicious mutation sites. The suspected pathogenic gene mutations were amplified with polymerase chain reaction (PCR) and analyzed with Sanger sequencing. Results: In this study, we found a five-generation pedigree with venous malformations that were suspected to be blue rubber bleb nevi. The cosegregation of disease phenotypes indicated the autosomal dominant mutation phenomenon. Heterozygous and inherited TEK mutations for the c.2545C>T substitution were detected in 3 affected members (II2, II14 and IV2), while the unaffected family members (II6 and IV7) carried the wild-type TEK gene, which cosegregated with the phenotype in this pedigree. Therefore, the novel missense variant c.2545C>T enriched the TEK mutation spectrum and may serve as a valuable genetic marker for the molecular diagnosis and prompt genetic counseling for BRBN. Conclusion: This study identified a novel inherited germline C2545T mutation in exon 15 of the TEK gene that can contribute to the pathology of pedigree-based venous malformations.
Incidence and Predictors of Pregnancy among HIV Positive Women on ART in North West Ethiopia, a Retrospective Cohort Study
Authors:   Department of Statistics, Debre Markos University, Debre Markos, Ethiopia, YF Gebrie , TM Dessie ,   Department of Applied Human Nutrition, Marie Stopes International, Ethiopia, D Yeshiwas ,   Department of Statistics, Debre Markos University, Debre Markos, Ethiopia
Published: April 2023

Objective: The objective of this study was to identify the prevalence and significant factors of incidence of pregnancy among HIV positive women under ART follow up. Methods: A retrospective cohort study was employed and a sample size of 429 was selected using simple random sampling technique. Both chi-square test of association and multiple binary logistic regression analysis were used. Results: The study has shown that 21.2% of women were pregnant during the follow-up. Variables like, WHO clinical stage, spouse’s HIV status, marital status, contraception use, body weight, occupation, CD4 count, age and time of ART were significant predictors of incidence of pregnancy. Conclusion: Women with advance WHO clinical stage were less likely to be pregnant. Women, who are married, employed, had never used contraceptive methods were more likely to had pregnancy. When CD4 cell count and body weight increase, incidence of pregnancy also increases and women who had longer time on ART were more likely to be pregnant. Health institutions and clinicians should be cautious when the patients have faced advanced WHO clinical stage and low CD4 count. We would like to put remarks of increasing employment of HIV Positive women, providing effective services of ART health care, and studying further investigation for the general wellbeing of mothers and their respective potentially born children.
Structure elucidation of olanzapine molecular salts by combining mechanochemistry and MicroED
Authors: Gogoi Diptajyoti , Sasaki Toshiyuki , Nakane Takanori , Kawamoto Akihiro , Hojo Hironobu , Kurisu Genji , Thakuria Ranjit
Published: April 2023

Olanzapine (OLN), an anti-psychotic drug, is one of the most widely studied pharmaceutical materials. Although OLN and most of their multicomponent solids are highly crystalline, some of their molecular salts are difficult to crystallize and optimization takes long time. After several batches of failed crystallization, we applied mechanochemistry and microcrystal electron diffraction (MicroED) for structure elucidation. This combined approach was successful not only in structure determination of the drug molecule but also in characterizing traces of impurity present in a bulk solid. This study demonstrates that the combined approach is fast and efficient for structure elucidation of pharmaceutical materials when generation of suitable single crystals is challenging.
Synthesis and Rhodium(I)-Catalyzed Annulative Cleavage of Bicy-clo[1.1.0]butyl Dihydroquinolines and Dihydropyridines
Authors: Borgini Matteo , Wipf Peter
Published: April 2023

Bicyclo[1.1.0]butane (BCB)-containing compounds are a highly strained class of reagents that feature a unique chemical reactivity, trig-gering “strain-release” reaction cascades, and provide unique products with considerable utility in the drug discovery field. The C-C bridgehead bond of BCB’s two fused cyclopropane rings holds significant π-character, allowing BCB-containing compounds to react with nucleophiles, electrophiles, radicals, π-systems, and carbenes. Herein, we reported the synthesis of new BCBs by the trapping of nu-cleophilic intermediates with quaternary ammonium ions derived from quinolines and pyridines. The resulting BCBs are then converted with high regioselectivity to unprecedented fused heterocycles in a rhodium(I)-catalyzed annulative rearrangement.
Charged Chiral Derivatization for Enantioselective Imaging of D-, L-2-hydroxyglutaric acid Using Ion Mobility Spectrometry/Mass Spectrometry
Authors: Sugiyama Eiji , Nishiya Yuki , Yamashita Kenji , Hirokawa Ryo , Iinuma Yoshiteru , Nirasawa Takashi , Mizuno Hajime , Hamashima Yoshitaka , Todoroki Kenichiro
Published: April 2023

A newly synthesized charged chiral tag enabled enantioselective imaging of D-, L-2-hydroxyglutaric acid, which are independently associated with the regulation of DNA methylation. The tag-conjugated diastereomers were ionized efficiently through MALDI, separated by ion mobility spectrometry, and further separated from other molecules in mass spectrometry. On-tissue chiral derivatization using the tag facilitated the visualization of different distributions of the two isomers in the mouse testis.
Parque Jardín Botánico, un ecosistema estratégico de Neiva para la educación en cultura ambiental
Authors: Murcia Murcia Nataly Vanessa , Flórez Cabrera Jorge Antonio , Farfán Calderón Jhorman Hervey
Published: April 2023

El deterioro ambiental es una problemática social que viene generando graves consecuencias para el ambiente en el que habitan los seres vivos, que incluyen la pérdida de servicios ecosistémicos, en el orden de regulación, provisión y cultural (Ministerio de Ambiente y Desarrollo Sostenible [MinAmbiente], 2011). Esto trae como consecuencia afectaciones a los seres humanos en las interacciones sociedad-naturaleza. Una de las causas de esta problemática es la escasa cultura ambiental presente en la comunidad en general, la cual se puede entender “como aquella postura ante la vida que permite cuidar y preservar el medioambiente, como asunto de interés para todo el mundo” (Cruz, 2008, p. 1).
Transportasi Yang Terintegrasi di Wisata Cagar Budaya Kota Tua Jakarta
Authors: Ratnawati Elfrida , Nurbaiti Siti
Published: April 2023

The purpose of writing  this article  is to discuss  integrated transportation in  old city  Jakarta. Thereare many problems faced and must be solved in order to achieve  the realization of integrated transportation, so as to create a neatly organized city and to travel to the old city area, tourists must feel comfort and time efficiency. The problem faced today is that transportation to the cultural heritage of the old city is very difficult because so much land transportation passes through the old city but is not properly arranged by the city government, so there is always congestion. This writing is a normati f legal research that uses secondary data and then analyzed descriptively. This research is important to answer the problem of using fast, convenient and efficient land transportation to achieve the cultural heritage tourism of the old city in the Jakarta area. The results of this study explain that the planning of the old city area of Jakarta so that  its potential is maximized through the arrangement of integrity and sustainable transportation issued by the DKI Jakarta City Government so that the arrangement of the old city is expected to become a valuable property center and grow the economy with the advantages of the old city as a business city and tourist city.

  

Tujuan penulisan artikel ini adalah membahas transportasi yang terintegrasi di Kota Tua Jakarta. Banyak permasalahan yang dihadapi dan harus diselesaikan agar dapat mencapai terwujudnya transpotasi yang terintegrasi, sehingga tercipta kota yang tertata dengan rapi dan untuk berwisata menuju wilayah kota tua para turis harus merasakan kenyamanan dan efesiensi waktu. Permasalahan yang dihadapi saat ini adalah transportasi menuju cagar budaya kota tua sangat sulit disebabkan begitu banyak transportasi darat yang melewati kota tua tetapi tidak ditata dengan baik oleh pemerintah kotanya, sehingga selalu terjadi kemacetan. Penulisan ini merupakan penelitian hukum normatif yang menggunakan data sekunder kemudian dianalisis secara dekriptif.   Penelitian ini penting dilakukan untuk menjawab permasalahan penggunaan transportasi darat yang cepat, nyaman dan efisien untuk mencapai wisata cagar budaya kota tua di wilayah Jakarta. Hasil penelitian ini menjelaskan bahwa perlu penataan kawasan kota tua Jakarta agar potensinya menjadi maksimal melalui penataan transportasi yang terintegritas dan berkelanjutan yang dikeluarkan oleh Pemerintah Provinsi DKI Jakarta agar penataan kota tua diharapkan menjadi pusat properti yang bernilai dan menumbuhkan ekonomi dengan keunggulan kota tua sebagai kota bisnis dan kota wisata.

  

  

  
Okul Öncesi Öğretmenlerinin Üstbilişsel Bilgi, Beceri ve Uygulamalara Yönelik Görüşleri (Preschool Teachers Views on Metacognitive Knowledge, Skills and Practices)
Authors: Nişan Mustafa , Temel Z. Fulya
Published: April 2023

Araştırmada, okul öncesi dönemde öğretmenlerin üstbilişsel bilgi, beceri ve uygulama hakkındaki görüş ve düşünceleri ile çocukların üstbilişsel bilgi ve becerilerini desteklemeye yönelik yaptıkları etkinlik planlarının incelenmesi amaçlanmıştır. Araştırmada nitel araştırma desenlerinden durum çalışması kullanılmıştır. Araştırma verileri görüşme ve doküman inceleme yöntemleri ile toplanmıştır. Görüşmelerden elde edilen verilerin dökümü yapılarak içerik analizi yapılmış, doküman inceleme için toplanan etkinlik planları ise Cambridgeshire Bağımsız Öğrenme (C.Ind.Le) Kodlama Şeması çerçevesinde kodlanarak betimsel analiz yapılmıştır. Araştırma sonucunda katılımcıların üstbilişsel bilgi, beceri ve uygulamalar hakkındaki görüşlerine göre Farkındalık, Planlama, Öğrenme Daveti, Uygulama ve Materyal olmak üzere altı tema ortaya çıkmıştır. Katılımcıların eğitim düzeylerine göre temalarda farklılıklar olduğu görülmüştür. Etkinlik planlarının, kodlama şemasına göre çözümlenmesi sonucunda katılımcıların üstbilişsel bilgi kategorisi, kişilerin bilgisi alt kategorisine ve üstbilişsel düzenleme kategorisi, izleme ve kontrol alt kategorilerine planlarında yer vermedikleri tespit edilmiş, planlarda da eğitim düzeylerine göre farklılıklar olduğu belirlenmiştir.
Strategi Pengendalian Stres pada Suami Pekerja Migran Indonesia
Authors:   Program Pendidikan Anak Usia Dini, Universitas Lampung, Irzalinda Vivi ,   Mahasiswa Program Doktor Ilmu Keluarga, Fakultas Ekologi Manusia, IPB University, Reviani Nia ,   Mahasiswa Program Doktor Ilmu Keluarga, Fakultas Ekologi Manusia, IPB University,   Kementerian Koordinator Bidang Pembangunan Manusia dan Kebudayaan, Silitonga Mirdat ,   Badan Kependudukan dan Keluarga Berencana Nasional,   Jaringan Peduli Anak Indonesia (JPAI), Puspitawati Herien ,   Departemen Ilmu Keluarga dan Konsumen, Fakltas Ekologi Manusia, IPB University, Muflikhati Istiqlaliyah ,   Departemen Ilmu Keluarga dan Konsumen, Fakltas Ekologi Manusia, IPB University
Published: April 2023

Stres dikategorikan ketika tuntutan dan beban tugas yang berat dialami seseorang namun tidak dapat menyelesaikannya, sehingga akan berdampak negatif pada tubuh seseorang. Respons tubuh tersebut disebut respons fisiologis dan psikologis. Suami akan mengalami stres saat istri memutuskan menjadi TKI karena merasa pekerjaan yang biasanya dikerjakan oleh istri sekarang menjadi tanggung jawab suami. Perginya istri menjadi masalah yang berat bagi suami. Banyaknya beban yang ditanggung suami dapat mengakibatkan suami mengalami gejala stres. Pentingnya pengendalian stres suami TKI sebagai masukan program relevan kerjasama kementerian yaitu integrasi pendidikan komunitas pembangunan keluarga (community parenting), meningkatkan akses kesehatan mental dan terapi keluarga bagi suami TKI.
CARTAZES MILITARES EM TEMPOS DE GUERRA: DA LUTA CONTRA O AUTORITARISMO AO MILITARISMO COMO POLÍTICA
Authors: Pereira Márcio José , Fernandes Thiago Todon Lopes
Published: April 2023

A pesquisa tem por objeto o discurso das nações autoritárias da Segunda Grande Guerra, partindo de cinco cartazes de
recrutamento emitidos em períodos de guerra. O recorte histórico consiste no Estados Unidos durante a
Primeira e a Segunda Guerra Mundial. O objetivo da pesquisa constitui-se em compreender e investigar
as estratégias nacionalistas utilizadas durante o processo de criação das imagens e os possíveis usos
desse meio de comunicação no ensino da história. Tratando o documento de uma propaganda
governamental, parte-se do seguinte aporte metodológico: Sandra Jatahy Pesavento (2008) e a
interpretação da narrativa enquanto imagem, Heloisa de Faria Cruz e Maria do Rosário da Cunha Peixoto
(2007) e o emprego da imprensa enquanto fonte histórica e Jacques Le Goff (1988) acerca do documento
enquanto monumento. Por tratar-se de uma pesquisa no campo da História Política, privilegia-se as
discussões presentes em Franciscon Falcon (1977) sobre a dinâmica histórica desse campo, René
Rémondt (2003) que refuta opiniões negativas acerca dessa linha e Serge Berstein (1988) sobre as
possibilidades que oferece a Nova História Política. Com a investigação, o discurso político pode ser
conjecturado, junto do contexto psicológico social nacionalista e econômico, que junto das técnicas de
análise gráfica, fomentaram o esboço de uma estratégia didática para o uso em sala de aula.
OSTEOSSÍNTESE NEONATAL BOVINA E O USO DE FIXADORES ESQUELÉTICOS EXTERNOS: RELATO DE CASO
Authors:   , DIAS RAFAELA OLIVEIRA
Published: April 2023

RESUMO

O presente trabalho de conclusão de curso relata as atividades técnicas desenvolvidas durante
a disciplina de Estágio Curricular Supervisionado da Faculdade do Centro do Paraná - UCP. As
atividades foram desenvolvidas no período de 01 de outubro a 30 de novembro de 2022 na
Unidade Didática Clínico Hospitalar – UDCH da Faculdade de Zootecnia e Engenharia de
Alimentos – FZEA/USP, localizados no Campus Fernando Costa, situado no município de
Pirassununga, no estado de São Paulo. Foi vivenciada a rotina hospitalar diária de atendimentos
e internamentos de grandes e pequenos ruminantes na área de clínica médica e clínica cirúrgica,
atendimentos externos realizados pela clínica ambulante, participação nas atividades do
laboratório de análises clínicas da instituição e a participação de projetos desenvolvidos no
setor. O estágio obrigatório desenvolveu – se sob supervisão do docente e médico veterinário
Dr. Eduardo Harry Birgel Junior. E a orientação da elaboração deste trabalho foi realizada pelo
professor Rodrigo Dorneles Tortorella do curso de Medicina Veterinária da Faculdade do
Centro do Paraná - UCP. São mencionadas neste, as atividades relativas ao período e a descrição
do local de estágio. No segundo momento, foi elaborada uma revisão bibliográfica sobre o tema
osteossíntese em bovinos com o uso de fixadores esqueléticos externos, dando maior
visibilidade a uma área ainda muito pouco explorada dentro da buiatria na medicina veterinária.
Em seguida, relatou-se o caso de uma bezerra zebuína recém-nascida apresentando fratura
completa e exposta da tíbia a qual necessitou de intervenção cirúrgica para sua redução.
EDUCAÇÃO, TECNOLOGIA E INCLUSÃO: DESAFIOS CONTEMPORÂNEOS
Authors: Santos Edinalba Brito Cabral dos , Cardoso Joel , Lima Reinaldo Feio , Nascimento Marcelo Cipriano do , Sena Michel Canuto de , Bastos Paulo Roberto Haidamus de Oliveira , Araújo Júnior João Carlos de , Souza Terezinha Sirley Ribeiro , Silva Márcia Simone da , Marques Marilene dos Santos , Ferreira Ivanilton , Pantoja Layssa Soares , Sansoni Karina Hubner Ferassolli , Alves Juliana Barbosa , Oliveira Alzenira Aquino de , Pedrosa Cleide Emília Faye , Barbosa Mônica de Gois Silva , Chaves Gabriela de Moraes , Santos Juliane Silva dos
Published: April 2023

A obra reúne escritas que promovem didáticas colaborativas, experiências, propostas e desafios.
Caso 2
Authors: Moura Ana Paula Carvalhal , Neme Glaucy Lane , Mattos Leandro Accardo de
Published: April 2023

• 30 anos, dismenorreia de moderada intensidade há cinco anos. Cirurgia de ooforectomia esquerda por torção ovariana na infância. Nunca fez tratamento clínico para dor pélvica e não deseja realizar cirurgia.
• Solicitada RM do abdome total e US especializada com preparo intestinal para pesquisa de endometriose.
Caso 4
Authors: Moura Ana Paula Carvalhal , Neme Glaucy Lane , Mattos Leandro Accardo de
Published: April 2023

• 31 anos, dismenorreia e infertilidade primária, dor no ombro direito (cíclica no período menstrual).
• Nega dispareunia, sintoma intestinal ou urinário.
• Toque: espessamento dos uterossacros e dor à mobilização do colo.
OS DESAFIOS DA EDUCAÇÃO INCLUSIVA NOS ESPAÇOS ESCOLARES MODERNOS
Authors: Fernandes Vagner , RIBEIRO DOMINGAS REGIANE OLIVEIRA
Published: April 2023

Recentemente foi aprovada a Reforma da Base Nacional Comum Curricular – BNCC, que reforça a importância e as diretrizes igualitárias que devem nortear a educação como um todo, realizando a integração e adaptação daqueles alunos que fazem parte da educação inclusiva. Porém, as críticas a essa nova reforma derivam de diversas fontes, principalmente de professores e responsáveis legais por esses alunos. Isso porque, apesar de indicar e exigir tais ações, o documento novamente ignora que deveria indicar de forma prática como isso deve ser feito, bem como destinar investimentos para o treinamento desses educadores e de adaptações estruturais das escolas para esses alunos. O objetivo geral do presente trabalho é analisar os desafios que ainda são enfrentados por alunos, pais e professores inseridos na educação especial e inclusiva no Brasil. A metodologia selecionada é descritiva e qualitativa, podendo ser definida como um estudo de caso realizado com 12 professores que atuam em unidades escolares nacionais. Os resultados apontam para as falhas na Reforma da BNCC e a negligência com a educação inclusiva e os alunos que nela estão inseridos.
Cytotoxic Activity of Ethanol Extract of Sesamum indicum Seeds to Cancer Cell Lines In Vitro
Authors: Shawkat Muayad S.
Published: April 2023

The present study was conducted to investigate the active constituents found in ethanolic extract of Sesamum indicum defatted seeds and it’s cytotoxic activity on three types of cancer cell lines (Hep-2, AMN-3, and RD) and one normal embryo rat cell line (Ref). Results of general chemical detection showed that ethanolic extract of sesame seeds contain phenols, tannins, saponines, glycosides, alkaloids, coumarines, and flavonoids. The qualitative and quantitative determination of sesamin bioactive compound using High Performance Liquid Chromatography (HPLC) analysis was carried out and compared with standard sesamin. It was found that the concentration of sesamin was 79.9% of ethanolic extract according to total peak area. Results of in vitro growth inhibition of sesame extract against cell lines demonstrated that the growth of these cells significantly decreased when compared with control cell lines (untreated), and the effects were dose and time- dependent for Hep-2, AMN-3,RD and Ref cells. A clear cytotoxic activity was observed after 72 hr at concentration( 1000 µg/ml) which reached (85.83%, 40.06%, and 20.20%) in the cell lines respectively, while the percentage of inhibition during exposure time of 48 hrs recorded 31.03% at a concentration of 1000µg/ml for RD cells
Acute Lymphoblastic Leukemia with a novel dic (11;11) (q24;q24) : A case report
Authors: Ismail Noor Hashim
Published: April 2023

Cytogenetic study was performed on a case of acute lymphoblastic leukemia . The chromosomal analysis for bone marrow cells by using G- banding technique showed A novel dic (11;11)(q24;q24) in 5 metaphases (15%) of 32 total metaphases studied , which has not been described previously in this leukemia type . Different abnormalities involving chromosome 11q have been reported as well . Novel rearrangement of 11q may reflect the heterogeneity of the genetic change which possibly refers to the differences in environmental and genetic factors of the Iraqi patients in comparison with other patients in another countries, which may contributes in the pathogenesis of acute lymphoblastic leukemia
Urinary tract infection among patients with bladder cancer : Bacteriological studies
Authors: Fadhil Rushdi Saadi
Published: April 2023

Certain infections, such as urinary tract infection may have an increased incidence in bladder cancer owing to physiological changes. One mechanism of initiating innate host defenses against bacteria in UTI’s is the production of cytokines. In this study, we investigated prevalence urinary tract infection among bladder cancer patients and the factors associated with the acquisition, and the description of the isolated pathogens in bladder cancer patients. This descriptive study was carried out through the period from January to may 2012 , 40 bladder cancer patients were collected from Baghdad Medical City , Medical City Teaching Laboratories and private laboratories and 20 case controls .The study groups were 40 urine samples from bladder cancer patients ; urine samples taken for tests, and cultures and 40 subjects as health control group from both sexes . The study showed that Staph. aureus was the most common microorganism isolated from UTI which represented (34 %). E.coli was found to be the second most common microorganism encountered in UTI (30.7%) Klebsiela spp. was found to be the third microorganism which represented (11.5%).Proteus spp. was fourth microorganism isolated which represented (15.3%) , while ( 7.6%) of microorganism was Pseudomonas, with p. value > 0.005 that mean no significant differences between the microorganisms that can cause infection in patient with other disease . The study also showed two groups , group (1) was patients with cancer bladder , In this group number of UTI was 65%(male &female) , while 35% of cancer bladder patients were without UTI with non-significant differences . Finally there is non-significant differences among groups of patients with Bladder cancer were divided into five groups , group one included (14) patients (35%) suffering from Bladder cancer only, group 2 included 10 patients (25%) suffering from bl. Cancer and D.M, group 3 included 7 patients (17.5%) suffering from bl. Cancer and hypertension , group 4 included 3 patients (7.5%) suffering from blood cancer and renal failure , group 5 included 6 patients (15.0) suffering from b. cancer and other diseases ( anemia , leukemia, CV and polycythemia).
Acid and Base modified Pectin from Orange Peel as an Effective Bio-adsorbent for Pb(II) and Cr(VI) from Textile Industry Wastewater
Authors: Hanifa Nur Lailatul , Afifah Afifah , Wijaya Destia Kusuma , Nurmazaya Nufus , Qomariyah Ani
Published: April 2023

Modifying the methoxyl group on pectin from Siam orange peel (Citrus nobilis) has been done. Pectin was obtained from the peel of Siam orange by extraction method. The modified pectin obtained were analyzed using the FT-IR (Fourier Transform-Infra Red Spectroscopy) method, the XRD (X-Ray Diffractometry), and surface appearance images using SEM (Scanning Electron Microscopy). Pb(II) and Cr(VI) metals which can be adsorbed by the adsorbent then analyzed by UV-Visible Spectrophotometer. The results of the FT-IR analysis was found that the modification of the methoxyl group was successful. XRD analysis showed that the modified pectin adsorbent produced amorphous properties. The maximum pH for Pb(II) adsorption was obtained, namely pH = 6 and the maximum pH for Cr(VI) adsorption was pH =7. The best adsorption time variation for Pb(II) was 240 min and for Cr(VI) was 500 min. The best adsorbent for adsorption of Pb(II) was base-modified pectin adsorbent, while the best adsorbent for adsorption of Cr(VI) was base-modified pectin adsorbent. It could be proven that base-modified pectin was able to adsorb Pb(II) and acid-modified pectin was able to absorb Cr(VI) better (Pb(II) 80% adsorption percentage and 90% Cr(VI) adsorption percentage) than previous studies, namely pectin without modification (adsorption percentage obtained 60-70%).
Optimalisasi Manajemen Kesiswaan pada Masa Pandemi Covid-19 di MTs Nurul Iman Kenali Asam Atas Kota Jambi
Authors: Najmul Hayat  , Sumirah  , Fitri Haryanti
Published: April 2023

This study aims to determine the Implementation of Student Management Implementation During the Covid-19 Pandemic at Mts Nurul Iman Kenali Asam Atas Jambi City. This research uses qualitative methods. By using data collection techniques in the form of observations, interviews, and documentation. The results of this study in terms of planning, organizing, and supervision have gone well, but in the aspect of implementing learning in students, especially in online learning during the Covid-19 pandemic, there are still many obstacles, namely not involving parents of students so that many students do not participate in these online learning activities because some of their parents do not have android cellphones and there are many obstacles also those who already have but do not have a learning quota.
Manajemen Sarana dan Prasarana di Pondok Pesantren Zulhijjah Batanghari pada Masa Pandemi Covid-19
Authors: Mukhlis  , A. Khalik  , Zainudin
Published: April 2023

This study aims to describe the management of facilities and infrastructure at the Zulhijjah Islamic Boarding School, Batang Hari Regency during the Covid-19 pandemic. This research uses qualitative approaches and research methods. The setting of this study is the zulhijjah islamic boarding school and the subjects of this study are santri and ustad / ustazah. The methods used are observation, interview, and documentation. Data validity using data types and data sources. The results of this study show that the Zulhijjah Islamic Boarding School has carried out steps to manage facilities and infrastructure; 1) Zulhijjah Islamic Boarding School conducts planning by recording the needs and provision of funds, 2) procurement of infrastructure according to the needs of the Islamic boarding school, 3) inventory is a recording of existing facilities and infrastructure in the Pesantren with details of the number and condition of goods in the Zulhijjah Islamic Boarding School, 4) maintenance of infrastructure as a whole, 5) elimination of facilities and infrastructure for damaged goods,  and it is not worth using again according to the procedure of mutual agreement first.
Analisis dan Landasan Teologis Kepemimpinan
Authors: Rusmini Rusmini
Published: April 2023

Leadership is a divine mandate. Therefore the Quran has a lot to say about this leadership. This article aims to explain the nature of leadership, the requirements to become a leader, as well as the qualifications to become a leader. This discussion becomes important when it is associated with the image of leadership.  To solve this problem, it is necessary to see how the support of the Quran provides justification in choosing leaders, the importance of the position of leaders in Islam, and the criteria for good and qualified leaders. This article concludes that the study of the Quran by taking a management approach, especially leadership studies, has long been carried out by management and leadership thinkers. Some experts conclude that leadership is not something special, but is a responsibility, sacrifice, hard work, authority to serve, even a pioneer of action. This research uses a library research method, namely literature study. The results of this research show that whoever becomes a leader, all his energy, enthusiasm, ambition, patience, liking, and direction must be carried out according to the guidance of the Quran.
Implementasi Tata Tertib Madrasah dalam Meningkatkan Karakter Disiplin Siswa di MA Swasta Al-Hidayah Tebo Ilir
Authors: Siti Raudhatul Jannah  , Savitri Riftiyanti , Eka Susilawati
Published: April 2023

This study aims to determine the strategy of school discipline in improving the disciplinary character of students at MAS Al-Hidayah Tebo Ilir. This research uses a qualitative approach. The informant selection technique uses purposive sampling. Data collection is carried out through observation, interviews, and documentation. Data analysis using interactive model analysis techniques by Miles and Huberman. The results showed that disciplinary character building is carried out through the application of discipline and habituation of activities that form the character of the discipline, such as arriving on time, praying on time, how to dress, and other extracurricular activities.
Pengaruh Pengelolaan Sistem Informasi Manajemen Berbasis Komputer terhadap Produktivitas Kerja Karyawan di Pondok Pesantren Ummul Masakin Kabupaten Batanghari
Authors: Jamaluddin Jamaludin , Dian Nisa Istofa  , Nur Annisah
Published: April 2023

This study aims to determine the influence of computer-based management information system management on productivity in Madrasah Aliyah Pondok Pesantren Ummul Masakin. This research is a quantitative study using a correlational research design, while the data analysis technique uses normality and product moment correlation tests. The results of this study found that in the 12 employees who were sampled there were results of product moment correlation testing, it was found that at the significance level of 5% = 0.576 and at the significance level of 1% = 0.708 it was rejected and accepted.
Транспортный каркас лесозаготовки как ключевой фактор развития лесной промышленности Пермского края
Authors: Букина Т.В. , Букин Е.К. , Третьякова Е.А.
Published: April 2023

В работе анализируется размещение мест лесозаготовки и лесопереработки в северных районах Пермского края во взаимосвязи с состоянием транспортной системы. Авторы приходят к выводу, что существующая транспортная сеть не позволяет устойчиво развиваться лесной промышленности данных территорий и не обеспечивает эффективное использование ресурсного потенциала лесного сектора. В процессе исследования была построена модель оптимального транспортного каркаса для северных территорий Пермского края, учитывающая их территориальные особенности и позволяющая обеспечить устойчивое развитие лесной промышленности благодаря формированию новых автотранспортных магистралей, которые дадут возможность транспортировать сырье к местам его переработки вне зависимости от сезона года и природно-климатических условий.
Multifunctional public platform WeChat as a tool for teaching to write scientific articles
Authors:   St. Petersburg State University, Qingguo Li
Published: April 2023

The possibilities of teaching Chinese students to write scientific articles in Russian using the multifunctional public platform of China WeChat are considered. According to the Federal State Educational Standards, not only graduate students need to be able to write scientific articles in Russian, write reports for conferences, etc., but also bachelors and masters. The combination of learning to write scientific articles and information technology greatly increases the effectiveness of learning. The WeChat public platform has a huge impact in China. In general, the WeChat platform is used as an intermediary for the publication of information, storage of materials and communication. However, taking into account the advantages of the platform, the article considers the linguodidactic potential of this platform, the sequence of actions for using it as an e-learning tool for writing scientific articles in Russian, and simulates individual learning situations that involve its use.
Reflection of the artistic life of Siberia in Grigory Potanin’s publications on art issues
Authors:   St. Petersburg Humanitarian University of Trade Unions, Khristolyubova Tatiana Pavlovna
Published: April 2023

The article analyzes the literary and journalistic activities of the key pre-revolutionary period for the city of Tomsk, the ideologist of Siberian regionalism, ethnographer and public figure Grigory Nikolaevich Potanin, concerning the regional aspect of artistic life. The materials of pre-revolutionary periodicals are used as sources. The author sets himself the task of identifying the features of G. N. Potanin ideas on Siberian regionalism (a local variant of regionalism) in texts on issues of art. It is noted that in his texts Grigory Potanin is trying to systematize the artistic heritage of Siberia, singles out the names of famous painters who came from the region, analyzes the creative heritage of Vasily Surikov. Grigory Potanin insists on the need to create art galleries in the region and regularly hold exhibitions of paintings, graphics and sculpture in order to increase the level of artistic taste among the population, and as a result, general education. The author also mentions that Grigory Potanin pays attention to the work of not only professional artists, but also masters of arts and crafts, urging the motifs drawn from local flora and fauna in ornaments. Being an ethnographer, Grigory Potanin does not miss the opportunity to talk about the life of the indigenous population of Altai on the examples of a number of paintings and graphic works by local artists, such as Grigory Gurkin, Lidia Bazanova and others. Accordingly, the great importance of Grigory Potanin contributes to the development of the local intelligentsia in Tomsk, largely linking the factors influencing this process with the establishment of higher educational institutions in the city. The ideologist of regionalism considers it necessary to culturally bring the commonalty and the intelligentsia closer together and zealously experiences the outflow of the intelligentsia from the city. It can be stated that the ideas expressed by Grigory Potanin on the pages of the Tomsk press had a huge impact on his contemporaries. Perhaps, in other historical circumstances, the regional ideology could take deeper roots in Siberia. Today we can only respect the literary heritage of Grigory Potanin and keep the memory of him as a man who sincerely loved his native land and sought to enrich it culturally.
Criteria for evaluating scientific activity and its results in library and information science
Authors:   federal state budget educational institution of higher education «Saint Petersburg State University of Culture», Zakharchuk Tat’jana Viktorovna , Breslav Anastasia Evgenievna ,   federal state budget educational institution of higher education «Saint Petersburg State University of Culture»
Published: April 2023

The features of the assessment of scientific activity and its results in the library and information sphere are considered. Criteria for evaluating the significance of the activities of a scientist in the library and information sphere and his works by the number of publications using citation and Hirsch indices are highlighted. An attempt was made to identify the attitude of scientists involved in research in this area to the accepted criteria for evaluating the results of scientific activity. The results of an anonymous survey of scientists involved in research in the field of library science, bibliography and book science are presented, the purpose of which is to analyze the effectiveness of various areas of evaluation of scientific activity in the library and information sphere. In the developed questionnaire, quantitative and qualitative criteria for evaluating scientific activity are proposed. The results of the survey showed that the attitude to the evaluation criteria is largely related to the role of a scientist (researcher, head of a scientific department, etc.), as well as to the peculiarities of the development of the field of scientific research itself.
Naming of US Public Libraries
Authors:   federal state budget educational institution of higher education «Saint Petersburg State University of Culture», Mashkara Aleksej Dmitrievich
Published: April 2023

The article considered the development of branding and naming in the marketing of library and information activities in Russia and in the USA. It is noted that in the professional literature of the USA, the problem of the library naming is not covered in detail but general branding issues. The names of the leading branches of American public library systems are analyzed in accordance with the author’s classification of naming (personalized, conceptual and toponymic). It is noted that most public libraries in the USA have a toponymic version of the name. A comparative analysis of the names of the New York Public Library branches was carried out for a comprehensive understanding of the features of American library naming. The prevalence of toponymic naming, when the name contains a direct reference to the location of the cultural institution, is proved by the example of New York libraries. In the process of comparative analysis, single indication of conceptual naming was identified (the name is associated with the reflection of the priority direction of the cultural institution activity, or has a special associative way at its basis). The author showed that a distinctive feature of personalized naming in the USA is the prevalence of libraries with the names of their founders or major patrons. It is concluded that attention to naming will increase as part of the overall marketing strategy of US cultural institutions.
Library Fund Science in the Perspective of Scientific Approaches
Authors:   federal state budget educational institution of higher education «Saint Petersburg State University of Culture», Varganova Galina Vladimirovna
Published: April 2023

Review of the monographic study: Stolyarov Yu. N. Library Fund Studies: selected. Moscow: Pashkov house, 2022. 507 p.: ill. ISBN 978-5-7510-0840-6.
Review of the textbook by E. I. Lelina «Organization of information and excursion activities» (Saint-Petersburg, 2022)
Authors:   federal state budget educational institution of higher education «Saint Petersburg State University of Culture», Mastenitsa Elena Nikolaevna
Published: April 2023

Lelina E. I. Organization of information and excursion activities: textbook / ed. A. Kh. Daudova, Yu. V. Krivosheeva. – Saint-Petersburg: Publ. house of Saint-Petersburg State Univ, 2022. – 274, [1] p.: ill. – ISBN 978-5-288-06273-5.