bluuebunny/crossref_metadata_2025 huggingface dataset:
Mapping of Inbound Flows in Supply Chain of Lithium-ion Industry in Indonesia
Authors: Sutopo Wahyudi , Zakaria Roni , Wardayanti Ari , Fahma Fakhrina ,   Industrial Engineering Department, Faculty of Engineering, Sebelas Maret University, Surakarta, Indonesia,   National Center for Sustainable Transportation Technology, Indonesia,   Industrial Engineering Department, Faculty of Engineering, Sebelas Maret University, Surakarta, Indonesia,   Industrial Engineering Department, Faculty of Engineering, Sebelas Maret University, Surakarta, Indonesia,   Industrial Engineering Department, Faculty of Engineering, Sebelas Maret University, Surakarta, Indonesia,   National Center for Sustainable Transportation Technology, Indonesia
Published: May 2018

The demand for lithium battery is currently high from the consumer side due to the widespread application of lithium-ion battery for electronics (laptops, notebooks, mobile phones, street lighting) and electric vehicles (electric cars and electric motors). In Indonesia, the research and industrialization on lithium-ion battery have been conducted to develop products such as for electric vehicles and street lighting. On the other hand, the relationship between suppliers, producers, distribution channels, and consumers has not been mapped. This mapping is intended to provide an overview of the strength of suppliers, involved manufacturers, and to determine the readiness of the value chain of lithium-ion battery to perform mass production. The approach in the mapping uses primary data and secondary data for the initial stage of inbound flows in supply chain of lithium-ion industry in Indonesia. Primary data are obtained from the questionnaires, which adopted from the value chain lithium-ion battery research in USA adjusted for Indonesian context. Meanwhile, the secondary data derived from literature reviews. The respondents in the study are 11 institutions consisting of manufacturers and R&D of lithium-ion battery in Indonesia. The results obtained are supplier mapping that provides the flow of lithium-ion battery, cell, module, and pack as well as the producers and consumers. The results could also be utilized to identify the valuable metrics in the supply chain of lithium battery industry.
War without Citizens
Authors: Rosow Stephen J.
Published: May 2018

Contestation over war memorialization can help democratic
theory respond to the current attenuation of citizenship in war in liberal
democratic states, especially the United States. As war involves more advanced
technologies and fewer soldiers, the relation of citizenship to war
changes. In this context war memorialization plays a particular role in refiguring
the relation. Current practices of remembering and memorializing war
in contemporary neoliberal states respond to a dilemma: the state needs to
justify and garner support for continual wars while distancing citizenship
from participation. The result is a consumer culture of memorialization that
seeks to effect a unity of the political community while it fights wars with
few citizens and devalues the public. Neoliberal wars fought with few soldiers
and an economic logic reveals the vulnerability to otherness that leads
to more active and critical democratic citizenship.
Egyptian Memories
Authors: Josipovici Gabriel
Published: May 2018

This is an excerpt from Gabriel Josipovici's life of his mother, Rabinovitch, who died in 1996 at the age of eighty-five. Sacha and her elder sister Vera, known as Chickie, were born in Helwan, near Cairo, in 1910 and 1909 respectively. Their father, a Jewish doctor from Odessa, died when the children were five and six, their mother was carried away by the epidemic which swept Egypt when they were ten and eleven. The greatest influence on the two little girls was their English nanny, who died the following year. After a brief period with their Syrian stepfather, Max Debbane, they went to live with their maternal grandparents, and it is here that the extract starts.
The Sephardic Voice of Elias Canetti
Authors: Esformes Maria
Published: May 2018

One of the most fascinating memoirs to appear in recent years is that of Elias Canetti, recipient of the 1981 Nobel Prize in Literature. his three-volume spiritual and intellectual autobiography is a complex and insightful rendering of his personal background and his creative development as a novelist, philosopher, and social critic. However, Canetti's autobiography is much more than a compelling account of the development of a great artist – it is a portrait of the tragic character of an entire era that witnessed the destruction of cultures and the way of life o many Jewish communities throughout Europe.
The Jewish Cemetery of Salonika in the Crossroads of Urban Modernisation and Anti-Semitism
Authors: Vassilikou Maria
Published: May 2018

In August 1946, the Board of Deputies of British Jews received a report about the situation of the Jewish cemetery of Salonika, the city which only three years ago had witnessed the destruction by the Germans of one of the most glorious Jewish communities of the Balkans. This detailed report aimed at summoning support for the protection of what was left of the ancient Jewish burial ground.
Poetry
Authors: Irie Kevin , Alvarez Al , Glasser Langille Carole , Marks Helene , Mail Michael , Ben-David Tirzah , Katz Steven B. , Faber Louis S. , Niditch B. Z.
Published: May 2018

The Venetian Ghetto

A Cemetery in New Mexico

Mourning and Melancholia

Refusing to Explain

Trachoma

Glenduffhill Cemetery Easterhouse

Immigrants, Haifa 1998

After the Event

Akeda

Holy Grammar

Desecration
Between Appropriating and Keeping Our Distance
Authors: Schlör Joachim
Published: May 2018

'What am I doing here?' During the preparation for this conference, 'Feeling at home in exile', I was able to accept the invitation to give a lecture, but for various reasons was not in a position to provide a clever title for it. When this proposal came I simply accepted and thought, something will turn up. Since then I have become more sceptical. At any rate, the theme 'majority and minority' should run through the text. But perhaps I will begin by explaining something of the circumstances in which the following text came about. If some degree of self-irony is to be found within it, I will be quite content.
Introduction
Authors: Lagenbacher Eric
Published: May 2018

The elections for the German Bundestag on 24 September 2017
saw heavy losses for the two governing parties—the Christian Democratic
Union (CDU) and the Social Democratic Party (SPD)—and the rise of the rightpopulist
Alternative for Germany (AfD). It took almost six months for a new
grand coalition to be formed in light of the extremely fragmented parliament.
Despite the good economic situation and relative calm domestically and internationally,
much change is occurring under the surface. Most importantly, the
country is preparing for the end of Chancellor Angela Merkel’s long tenure.
Who and what will come next? Can the surging AfD be contained? Will Germany
step up into the leadership role for which so many have called?
Kan-di(e)-dat?
Authors: Mushaben Joyce Marie
Published: May 2018

Angela Merkel’s four national election campaigns offer a unique
opportunity to explore the salience of gender in defining “competent leadership”
in unified Germany. Women-friendly themes were deliberately avoided
by the candidate and her party during her first two campaigns, but Merkel’s
personal popularity rendered gender a positive asset during her third run for
the Chancellorship in 2013. The 2017 campaign accorded new salience to gender
as an electoral variable, albeit with a twist. The new dilemma for Germany’s
first female leader was rooted in the need to win back alienated, if
apolitical conservative men, attracted to an increasingly xenophobic Alternative
for Germany. Although the GDR gender regime actively supported working
women, eastern men appear to feel particularly threatened by the concrete
advances towards gender equality witnessed across Germany since unification.
Information and Communication Technology Systems to Improve Quality of Life and Safety of Alzheimer's Disease Patients: A Multicenter International Survey
Authors: Pilotto Alberto , D'Onofrio Grazia , Benelli Edoardo , Zanesco Antonio , Cabello Ana , Margelí M. Carmen , Wanche-Politis Sophia , Seferis Kostas , Sancarlo Daniele , Kilias Dimitrios ,   on behalf of the HOPE Investigators
Published: May 2018

Within the frame of the European Commission funded Smart Home for Elderly People (HOPE) Project, relatives/caregivers of 223 Alzheimer's Disease (AD) patients were recruited in Italy, Spain, and Greece for a multicenter international survey on the potential role of Information and Communication Technology system (ICT-systems) for AD patients. A five-minute video on HOPE ICT-systems was shown, and all relatives/caregivers completed a 13-item questionnaire that evaluated the potential role of: A) ICT-systems in improving quality of life, care, and safety; B) devices for monitoring personal movements, medication use, and ambient environmental conditions; C) devices to improve communication, home-based rehabilitation, and reduction of specific risks; and D) possible agreement in using ICT-systems by AD patients. Relatives/caregivers reported that ICT-systems could be very useful to improve: A) quality of life (66.4%), care (56.1%), and safety (87.0%); B) monitoring bed rest and movements (80.7%), medication use (87.4%), and ambient environmental conditions (85.2%); and C) emergency communication (83.4%). Relatives/caregivers reported that ICT-systems could be significantly more useful for AD patients aged 75–84 than patients aged <75 or ≥85 years (p < 0.0001) and with moderate than mild or severe dementia (p < 0.0001). Relatives/caregivers aged ≥50 years and with low educational level considered ICT-systems more useful than relatives/caregivers aged <50 years (p < 0.0001) and with high educational level (p < 0.0001). In conclusion, relatives/caregivers considered that the HOPE ICT-system could be useful to improve the management of AD patients.
Phytic Acid as a Potential Treatment for Alzheimer's Pathology: Evidence from Animal and in vitro Models
Authors: Anekonda Thimmappa S. , Wadsworth Teri L. , Sabin Robert , Frahler Kate , Harris Christopher , Petriko Babett , Ralle Martina , Woltjer Randy , Quinn Joseph F.
Published: May 2018

Alzheimer's disease (AD) causes progressive, age-dependent cortical and hippocampal dysfunction leading to abnormal intellectual capacity and memory. We propose a novel protective treatment for AD pathology with phytic acid (inositol hexakisphosphate), a phytochemical found in food grains and a key signaling molecule in mammalian cells. We evaluated the protective and beneficial effects of phytic acid against amyloid-β (Aβ) pathology in MC65 cells and the Tg2576 mouse model. In MC65 cells, 48–72-hour treatment with phytic acid provided complete protection against amyloid precursor protein-C-terminal fragment-induced cytotoxicity by attenuating levels of increased intracellular calcium, hydrogen peroxide, superoxide, Aβ oligomers, and moderately upregulated the expression of autophagy (beclin-1) protein. In a tolerance paradigm, wild type mice were treated with 2% phytic acid in drinking water for 70 days. Phytic acid was well tolerated. Ceruloplasmin activity, brain copper and iron levels, and brain superoxide dismutase and ATP levels were unaffected by the treatment. There was a significant increase in brain levels of cytochrome oxidase and a decrease in lipid peroxidation with phytic acid administration. In a treatment paradigm, 12-month old Tg2576 and wild type mice were treated with 2% phytic acid or vehicle for 6 months. Brain levels of copper, iron, and zinc were unaffected. The effects of phytic acid were modest on the expression of AβPP trafficking-associated protein AP180, autophagy-associated proteins (beclin-1, LC3B), sirtuin 1, the ratio of phosphorylated AMP-activated protein kinase (PAMPK) to AMPK, soluble Aβ1-40, and insoluble Aβ1-42. These results suggest that phytic acid may provide a viable treatment option for AD.
Linkage to the 8p21.1 Region Including the CLU Gene in Age at Onset Stratified Alzheimer's Disease Families
Authors: Sillén Anna , Lilius Lena , Forsell Charlotte , Kimura Toru , Winblad Bengt , Graff Caroline
Published: May 2018

Two powerful genome-wide association studies have recently reported significant association between sporadic late-onset Alzheimer's disease (AD) and markers at the CLU locus in chromosome 8p. In this study, we have stratified our previously analyzed 109 Swedish AD families according to range in age at onset and performed whole-genome linkage analysis and subsequent fine-mapping in 8p21. The subgroup analyzed in the fine-mapping consisted of 28 families with AD, having a within-family onset-range not exceeding 8 years and an age at onset between 49 ≤ 70 years. A maximum non-parametric linkage peak (LOD = 3.5) was found between markers D8S1809 and 236c6-1. Intriguingly this linked 9.5cM region contains clusterin (CLU), which is one of the two top susceptibility genes for AD. Our finding may be a reflection of linkage to the CLU susceptibility gene, in the same way as familial AD has previously been linked to the APOE locus.
A Novel Progranulin Mutation Causing Frontotemporal Lobar Degeneration with Heterogeneous Phenotypic Expression
Authors: Rossi Giacomina , Piccoli Elena , Benussi Luisa , Caso Francesca , Redaelli Veronica , Magnani Giuseppe , Binetti Giuliano , Ghidoni Roberta , Perani Daniela , Giaccone Giorgio , Tagliavini Fabrizio
Published: May 2018

Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disorder characterized by behavioural disturbances and cognitive decline. Here we describe an Italian family with FTLD showing remarkable phenotypic heterogeneity. Based on low plasma levels of progranulin, we analyzed the progranulin gene (GRN) in two patients with early onset and found the novel frame-shift mutation T278SfsX7. mRNA analysis confirmed the null effect of the mutation. The patients were homozygous for H1 MAPT haplotype, a disease modifier factor that can account for early age at onset. Being predictive for GRN null mutations, plasma progranulin dosage should be included in diagnostic work-up of dementia.
A Novel Blood Test for the Early Detection of Alzheimer's Disease
Authors: Rye Phil. D. , Booij Birgitte Boonstra , Grave Gisle , Lindahl Torbjørn , Kristiansen Lena , Andersen Hilde-Marie , Horndalsveen Peter O. , Nygaard Harald A. , Naik Mala , Hoprekstad Dagne , Wetterberg Peter , Nilsson Christer , Aarsland Dag , Sharma Praveen , Lönneborg Anders
Published: May 2018

Despite a variety of testing approaches, it is often difficult to make an accurate diagnosis of Alzheimer's disease (AD), especially at an early stage of the disease. Diagnosis is based on clinical criteria as well as exclusion of other causes of dementia but a definitive diagnosis can only be made at autopsy. We have investigated the diagnostic value of a 96-gene expression array for detection of early AD. Gene expression analysis was performed on blood RNA from a cohort of 203 probable AD and 209 cognitively healthy age matched controls. A disease classification algorithm was developed on samples from 208 individuals (AD = 103; controls = 105) and was validated in two steps using an independent initial test set (n = 74; AD = 32; controls = 42) and another second test set (n = 130; AD = 68; controls = 62). In the initial analysis, diagnostic accuracy was 71.6 ± 10.3%, with sensitivity 71.9 ± 15.6% and specificity 71.4 ± 13.7%. Essentially the same level of agreement was achieved in the two independent test sets. High agreement (24/30; 80%) between algorithm prediction and subjects with available cerebrospinal fluid biomarker was found. Assuming a clinical accuracy of 80%, calculations indicate that the agreement with underlying true pathology is in the range 85%-90%. These findings suggest that the gene expression blood test can aid in the diagnosis of mild to moderate AD, but further studies are needed to confirm these findings.
Mapping the Altered Patterns of Cerebellar Resting-State Function in Longitudinal Amnestic Mild Cognitive Impairment Patients
Authors: Bai Feng , Liao Wei , Watson David R. , Shi Yongmei , Yuan Yonggui , Cohen Alexander D. , Xie Chunming , Wang Yi , Yue Chunxian , Teng Yuhuan , Wu Di , Jia Jianping , Zhang Zhijun
Published: May 2018

The cerebellum is known to be a relatively well preserved structure, but subtle alterations may occur early in the evolution of Alzheimer's disease (AD). Amnestic mild cognitive impairment (aMCI) patients appear to be particularly vulnerable to AD. However, little is currently known whether altered patterns of cerebellar function occur in aMCI patients. 26 aMCI patients and 18 well-matched healthy controls underwent a baseline resting-state functional magnetic resonance imaging (fMRI) scan. After a mean follow-up period of 20 months, the subjects who successfully completed baseline fMRI scans underwent a further follow-up scan, while spontaneous activation and functional connectivity of the cerebellum were explored by using resting-state fMRI. Compared to controls, increased amplitude of low frequency fluctuation of the posterior cerebellar lobe may contribute to the underlying mechanisms affected, while greater decreased functional connections to the posterior cerebellar lobe were identified in the longitudinal study of aMCI patients. This suggests that abnormal functional connectivity of the cerebellum may offer a more sensitive and possibly preferred index of functional disturbance than regional activity measures in aMCI patients. The cerebellum may be partly related to the underlying mechanisms of aMCI, and it could help guide subsequent investigations designed to specify the precise functional role of cerebellum in aMCI patients.
JNK3 as a Therapeutic Target for Neurodegenerative Diseases
Authors: Antoniou Xanthi , Falconi Mattia , Di Marino Daniele , Borsello Tiziana
Published: May 2018

c-Jun N-terminal kinases (JNKs) and in particular JNK3 the neuronal specific isoform, have been recognized as important enzymes in the pathology of diverse neurological disorders. Indeed, several efforts have been made to design drugs that inhibit JNK signaling. The success that characterized the new generation of cell permeable peptides raise the hope in the field of neurodegeneration for new therapeutic routes. However, in order to design new and more efficient therapeutical approaches careful re-examination of current knowledge is required. Scaffold proteins are key endogenous regulators of JNK signaling: they can modulate spatial and temporal activation of the JNK signaling and can thus provide the basis for the design of more specific inhibitors. This review focuses on delineating the role of scaffold proteins on the regulation of JNK signaling in neurons. Furthermore the possibility to design a new JNK3 cell permeable peptide inhibitor by targeting the β-arrestin-JNK3 interaction is discussed.
Dysfunction of the Fusion of Pre-Synaptic Plasma Membranes and Synaptic Vesicles Caused by Oxidative Stress, and its Prevention by Vitamin E
Authors: Arai Masaya , Saito Mitsunari , Takatsu Hirokatsu , Fukui Koji , Urano Shiro
Published: May 2018

To define whether hyperoxia induces the dysfunction of membrane fusion between synaptic vesicles with pre-synaptic plasma membranes in the nerve terminals, and whether vitamin E prevents this abnormal event, we investigated the influence of hyperoxia on the fusion ability of isolated synaptic vesicles and the inside-out type pre-synaptic plasma membrane vesicles from rat brain using the fluorescence tracing method. The membrane fusion ability of both membranes from rats subjected to hyperoxia was markedly decreased compared with the membranes from a normal rat. Rats subjected to hyperoxia in the form of oxidative stress showed significant increases in the levels of thiobarbituric acid reactive substances (TBARS), conjugated dienes, and protein carbonyl moieties in both synaptic vesicles and pre-synaptic plasma membranes. When rats were supplemented with vitamin E, these abnormalities were inhibited even when rats were subjected to hyperoxia.
Three Postulates to Help Identify the Cause of Alzheimer's Disease
Authors: de la Torre Jack C.
Published: May 2018

Two centuries ago, the German bacteriologist Robert Koch proposed three postulates to support a causal relationship between a specific microbe and an infectious disease. Similarly, three postulates are formulated here to help evaluate hypothetical proposals attempting to explain the pathogenesis of Alzheimer's disease (AD). The first postulate requires that the cause of AD precedes the cognitive decline and neurodegenerative pathology that characterize AD. This rule identifies a primary event from a neuropathological effect generated by the disease process. The second postulate stipulates that interventions aimed at the proposed causal event should prevent or reverse the cognitive and neurodegenerative pathology associated with AD prior to disease onset. This postulate emphasizes prevention or reversal of emerging neurocognitive pathology considerably before AD onset. If the first and second postulate requirements are met, the third postulate follows that interventions targeting the causal event should significantly lower the incidence of AD. For a causal hypothesis to be considered “likely” pathogenic to AD, support from all three postulates is a requisite. The pragmatic potential of the three postulates was applied to seven proposals using evidence-based meta-analysis mainly from randomized controlled trials. Proposals included the amyloid-β, cell cycle, cholinergic, inflammatory, oxidative stress, tau, and vascular hypotheses. Clinical evidence derived from each proposal formed the basis for an inferential conclusion based on the level of confidence provided by the trial data. The three postulates may challenge or help validate a proposed cause-effect relationship to AD and serve as a useful model for designing more intelligent therapeutic interventions aimed at preventing AD.
Amyloid-β-Induced Amyloid-β Secretion: A Possible Feed-Forward Mechanism in Alzheimer's Disease
Authors: Marsden Ian T. , Minamide Laurie S. , Bamburg James R.
Published: May 2018

Amyloid-β (Aβ) peptides, 36–43 amino acids in length, are produced from β- and γ-secretase cleavage of the amyloid-β protein precursor (AβPP), and are one of the causative agents of Alzheimer's disease (AD). Here we show that an ELISA can detect total rodent Aβ without interference from physiological concentrations of human Aβ. In cultured dissociated rat cortical neurons and rat and mouse hippocampal organotypic slices, we apply the assay to measure the production of Aβ in response to treatment with hydrogen peroxide, a known stimulator of Aβ secretion, or human Aβ dimer/trimer (Aβd/t), fractionated from the culture medium of 7PA2 cells. Peroxide increases Aβ secretion by about 2 fold, similar to results from previous reports that used a different assay. Of greater significance is that physiologically relevant concentrations (~250 pM) of human Aβd/t increase rodent Aβ secretion from cultured rat cortical neurons by >3 fold over 4 days. Surprisingly, neither treatment with peroxide nor human Aβd/t leads to accumulation of intracellular Aβ. Human Aβd/t increased >2 fold the Aβ secreted by organotypic hippocampal slices from tau knock-out mice whether or not they expressed a human tau transgene, suggesting tau plays no role in enhanced Aβ secretion. Together, these results support an Aβ-mediated feed-forward mechanism in AD progression.
Replication of BIN1 Association with Alzheimer's Disease and Evaluation of Genetic Interactions
Authors: Carrasquillo Minerva M. , Belbin Olivia , Hunter Talisha A. , Ma Li , Bisceglio Gina D. , Zou Fanggeng , Crook Julia E. , Pankratz V. Shane , Sando Sigrid B. , Aasly Jan O. , Barcikowska Maria , Wszolek Zbigniew K. , Dickson Dennis W. , Graff-Radford Neill R. , Petersen Ronald C. , Morgan Kevin ,   for the Alzheimer's Research Trust Consortium (ART), Younkin Steven G.
Published: May 2018

The most recent late-onset Alzheimer's disease (LOAD) genome-wide association study revealed genome-wide significant association of two new loci: rs744373 near BIN1 (p = 1.6 × 10−11) and rs597668 near EXOC3L2/BLOC1S3/MARK4 (p = 6.5 × 10−9). We have genotyped these variants in a large (3,287 LOAD, 4,396 controls), independent dataset comprising eleven case-control series from the USA and Europe. We performed meta-analyses of the association of these variants with LOAD and also tested for association using logistic regression adjusted by age-at-diagnosis, gender, and APOE ε4 status. Meta-analysis results showed no evidence of series heterogeneity and logistic regression analysis successfully replicated the association of BIN1 (rs744373) with LOAD with an odds ratio (OR = 1.17, p = 1.1 × 10−4) comparable to that previously reported (OR = 1.15). The variant near EXOC3L2 (rs597668) showed only suggestive association with LOAD (p = 0.09) after correcting for the presence of the APOE ε4 allele. Addition of our follow-up data to the results previously reported increased the strength of evidence for association with BIN1 (11,825 LOAD, 32,570 controls, rs744373 Fisher combined p = 3.8 × 10−20). We also tested for epistatic interaction between these variants and APOE ε4 as well as with the previously replicated LOAD GWAS genes (CLU: rs11136000, CR1: rs3818361, and PICALM: rs3851179). No significant interactions between these genes were detected. In summary, we provide additional evidence for the variant near BIN1 (rs744373) as a LOAD risk modifier, but our results indicate that the effect of EXOC3L2 independent of APOE ε4 should be studied further.
Changing Spectrum of Diseases in Our Clinical Practice
Authors: Uddin Khwaja Nazim
Published: May 2018

Abstract not availableBirdem Med J 2018; 8(2): 91-98
Outcome of Pancreatic Head Coring in as Key Surgical Treatment in Head Dominant Chronic Pancreatitis in Tertiary Referral Centers of Bangladesh
Authors: Rabbi Hashim , Rashid Md Mamunur , Ahmed AHM Tanvir , Raihan HM Sabbir , Nayeem Sarder Rizwan , Ali Mohammad , Hakim HA Nazmul , Chowdhury Ajmal Quader , Sarder Mahmud Mohammad
Published: May 2018

Background: Pancreatic head coring procedure, an organ preserving surgery in which diseased head of pancreas is cored with drainage of main pancreatic duct by lateral pancreatico-jejunostomy. Chronic pancreatitis is a persistently occurring inflammatory disease that causes pancreatic duct stones or calcification, stricture, dilatation of pancreatic duct and irreversible morphological changes resulting intractable pain and losses of exocrine and endocrine function. Appropriate management protocol recognizing underlying pathology, can prevent complications and improves the quality of life. Apart from ductal decompression, in Frey’s’ procedure resection of the “pacemaker of pain” (Head of the pancreas) gives excellent outcome.Methods: In this prospective observational study, we have intended to further validate the Frey’s procedure an effective surgical method in head dominant severe chronic pancreatitis. The study was carried out on 106 Bangladeshi patients who underwent Frey’s Procedure with Lateral Pancreaticojejunostomy from January 2000 to December 2017.Result: The study revealed 51 patients (48.11%) were in 3rd decade of life with 45 male and 61 female. We found 77 patients presented with diabetes mellitus, mostly on insulin. Steatorrhoea was noted in 39 patients and Malnutrition in 79 patients. Visual Analog Scale (VAS) was used for scoring pain. Postoperative morbidity was noted in 29 patients 27.35 % cases, but there was no anastomotic leakage or mortality in the immediate postoperative period in our series.Conclusion: Quality of life has always been the most important decisive factor for patients with severe chronic Pancreatitis. Pain is the predominant clinical feature and very difficult to control. Correction of diabetes and malnutrition are major challenges too. This study revealed, Frey’s procedure with adequate ductal clearance with wide pancreato-jejunal anastomosis in head dominant severe chronic pancreatitis is key to better pain control, improves quality of life and prevents recurrence.Birdem Med J 2018; 8(2): 151-158
Renal Transplantation-Anaesthetic Experience of 12 years: A Retrospective Study
Authors: Shaheen Md Shafiul Alam , Sardar Kawsar , Chowdhury AKM Nurnobi , Hasan Mahbubul , Rahman Mashfiqur , Mansur Mohammad Abul , Hasan Mirza Mahbubul , Chowdhury ATM Mowladad , Rahman Shafiqur
Published: May 2018

Background: Renal transplantation is the preferred treatment for end stage renal disease. Patients undergoing renal transplant surgery have several high risk features like cardiovascular diseases, diabetes mellitus and need for haemodyalysis. Renal transplant anaesthesia requires a thorough understanding of the metabolic and systemic abnormalities in end stage renal disease, familiarity with transplant medicine and expertise in managing and optimizing these patients for the best possible outcome. The aim of this study was to find out the characteristics of patients, causes of ESRD, anaesthetic management and the impact of pre-existing diseases on intraoperative or early postoperative complications of the recipients.Methods: In this retrospective study we described our experiences of 124 cases of living transplants from November 2004 – December 2016. We reviewed their medical history and noted age, sex, blood groups, causes of ESRD and history of dialysis. Preoperative investigation and preparation, as well as details of anaesthetic management, were also recorded.Results: General anaesthesia was performed in almost 97% of patients and for the rest of them, combined epidural and general anesthesia were done. The age of the patients was in the range of 15 – 65 years, with the majority of 30 - 39 years group. The mean of surgery duration was 4.5 (±1.20SD) hours. The most significant point during surgery is keeping the mean arterial pressure > 90mm Hg.Conclusions: Preoperative patient optimization, intraoperative haemodynamic stability and postoperative care of renal transplant patients have contributed to the success of renal transplant programmed in our hospital.Birdem Med J 2018; 8(2): 167-171
Serum Magnesium Level in Gestational Diabetes Mellitus in a Tertiary Care	Hospital of Bangladesh
Authors: Mishu FA , Muttalib MA , Naher S , Tabassum R , Ahmed R , Aziz Z , Wahab MAKA , Akhter S , Khan MRA
Published: May 2018

Gestational diabetes mellitus (GDM) is characterized by glucose intolerance during pregnancy. GDM is associated with an increased incidence of congenital abnormalities usually aggravated by maternal magnesium deficiency. Magnesium is one of the essential trace elements for normal embryogenesis and foetal growth and its deficiency increases mortality and morbidity rate of mothers, embryos and neonates. The present study was undertaken to evaluate the association of serum magnesium with GDM in second and third trimester of pregnancy. This case-control study was conducted in Mymensingh Medical College Hospital during the period from July 2013 to June 2014 to evaluate the association of serum magnesium with GDM in Bangladeshi women. A total of 172 subjects were recruited in this study; among them eighty six women with GDM were selected as case (Group-I) and eighty six healthy pregnant women were taken as control (Group- II). The cases again were subdivided as Group Ia and Ib at second and third trimester respectively. Controls also were subdivided as Group IIa and IIb at second and third trimester respectively. Student's unpaired 't' test was used to compare the data between groups. For analytical purpose 95% confidence limit (p<0.05) was taken as level of significance. Serum magnesium level was significantly decreased in cases compared to that of controls. It was significantly lowered (p<0.001) in cases Gr-Ia (1.3884±0.255 mg/dl) than controls Gr-IIa (1.6651±0.304 mg/dl) at second trimester. The result was also significantly (p<0.001) lowered when compared between cases Gr-Ib (0.9349±0.145 mg/dl) and controls Gr-IIb (1.6674±0.308 mg/dl) at third trimester. The study shows that serum magnesium level is decreased in pregnancy with GDM. So estimation of serum magnesium level may be done in every GDM cases to reduce the incidence of magnesium related complications by timely intervention.Bangladesh J Med Biochem 2016; 9(2): 59-62
THE EVALUATIVE IMAGE OF THE CITY THROUGH THE LENS OF SOCIAL MEDIA: CASE STUDY OF MELBOURNE CBD
Authors: MOTAMED Bahareh , MAHMOUDI FARAHANI Leila
Published: May 2018

The ubiquitous of smartphones and access to social media provide a new way of interacting with urban environments. The archived and shared images on social media not only indicate users’ interest but also they embody what users want to remember from a city. To investigate the evaluative image of a city through published images, Melbourne CBD has been selected as a case study. An in-depth survey of 460 geotagged photos from CBD in Flickr, 500px and Instagram (during 2014), provides an opportunity for city planners and urban designers to transform the image of a city to be more likeable, meaningful.
A SPATIAL DIALOGUE OF HERITAGE VILLAGE BETWEEN KAUMAN IN SEMARANG AND SEOCHON IN SEOUL TOWARD PRESERVATION DEVELOPMENT
Authors: SUPRAPTI Atiek , KIM Saehoon , PANDELAKI Edward E. , FIRMANDHANI Satriya W.
Published: May 2018

Semarang is one of big cities in Indonesia contains of multy ethnics. They traditionally settled down inside a group of villages. Kauman is the cultural heritage of Muslim settlement in Semarang. The peculiarity of local Muslims in Java’s coastline and the strong social cohesion colour the people’s daily life. Seochon in Seoul is a historic area and is the home for more than 670 hanoks. In 2008, Seoul Metropolitan Government issued a conservation plan and recruited a team of architects and academics to observe and investigate Seochon’s condition and discover the possibilities of conservation there. It turned out that Seochon has a great potential for revitalization. Nowadays, Seochon has become a tourism destination having both traditional and contemporary cultural value. This research aims to understand the efforts of preservation done by the government and public participation for the sake of preservation. This research used primary and secondary data and comparative study methods. Seochon village has been successful in developing preservation and preservation placed as the best example. The result of research showed that the conservation and preservation of Kauman needs a workable rules to manage and investigate the potential and resources. The result of this research could be used to any other cases similar to Kauman.
Dynamical Constraints on Nontransiting Planets Orbiting TRAPPIST-1
Authors: Jontof-Hutter Daniel , Truong Vinh H. , Ford Eric B. , Robertson Paul , Terrien Ryan C.
Published: May 2018

We derive lower bounds on the orbital distance and inclination of a putative planet beyond the transiting seven planets of TRAPPIST-1, for a range of masses ranging from 0.08 M
Jup to 3.5 M
Jup. While the outer architecture of this system will ultimately be constrained by radial velocity measurements over time, we present dynamical constraints from the remarkably coplanar configuration of the seven transiting planets, which is sensitive to modestly inclined perturbers. We find that the observed configuration is unlikely if a Jovian-mass planet inclined by ≥3° to the transiting planet exists within 0.53 au, exceeding any constraints from transit timing variations (TTV) induced in the known planets from an undetected perturber. Our results will inform RV programs targeting TRAPPIST-1, and for near coplanar outer planets, tighter constraints are anticipated for radial velocity (RV) precisions of ≲140 m s−1. At higher inclinations, putative planets are ruled out to greater orbital distances with orbital periods up to a few years.
Obliquity Variations of Habitable Zone Planets Kepler-62f and Kepler-186f
Authors: Shan Yutong , Li Gongjie
Published: May 2018

Obliquity variability could play an important role in the climate and habitability of a planet. Orbital modulations caused by planetary companions and the planet’s spin axis precession due to the torque from the host star may lead to resonant interactions and cause large-amplitude obliquity variability. Here we consider the spin axis dynamics of Kepler-62f and Kepler-186f, both of which reside in the habitable zone around their host stars. Using N-body simulations and secular numerical integrations, we describe their obliquity evolution for particular realizations of the planetary systems. We then use a generalized analytic framework to characterize regions in parameter space where the obliquity is variable with large amplitude. We find that the locations of variability are fine-tuned over the planetary properties and system architecture in the lower-obliquity regimes (≲40°). As an example, assuming a rotation period of 24 hr, the obliquities of both Kepler-62f and Kepler-186f are stable below ∼40°, whereas the high-obliquity regions (60°–90°) allow moderate variabilities. However, for some other rotation periods of Kepler-62f or Kepler-186f, the lower-obliquity regions could become more variable owing to resonant interactions. Even small deviations from coplanarity (e.g., mutual inclinations ∼3°) could stir peak-to-peak obliquity variations up to ∼20°. Undetected planetary companions and/or the existence of a satellite could also destabilize the low-obliquity regions. In all cases, the high-obliquity region allows for moderate variations, and all obliquities corresponding to retrograde motion (i.e., >90°) are stable.
Recovering the Physical Properties of Molecular Gas in Galaxies from CO SLED Modeling
Authors: Kamenetzky J. , Privon G. C. , Narayanan D.
Published: May 2018

Modeling of the spectral line energy distribution (SLED) of the CO molecule can reveal the physical conditions (temperature and density) of molecular gas in Galactic clouds and other galaxies. Recently, the Herschel Space Observatory and ALMA have offered, for the first time, a comprehensive view of the rotational J = 4−3 through J = 13−12 lines, which arise from a complex, diverse range of physical conditions that must be simplified to one, two, or three components when modeled. Here we investigate the recoverability of physical conditions from SLEDs produced by galaxy evolution simulations containing a large dynamical range in physical properties. These simulated SLEDs were generally fit well by one component of gas whose properties largely resemble or slightly underestimate the luminosity-weighted properties of the simulations when clumping due to nonthermal velocity dispersion is taken into account. If only modeling the first three rotational lines, the median values of the marginalized parameter distributions better represent the luminosity-weighted properties of the simulations, but the uncertainties in the fitted parameters are nearly an order of magnitude, compared to approximately 0.2 dex in the “best-case” scenario of a fully sampled SLED through J = 10−9. This study demonstrates that while common CO SLED modeling techniques cannot reveal the underlying complexities of the molecular gas, they can distinguish bulk luminosity-weighted properties that vary with star formation surface densities and galaxy evolution, if a sufficient number of lines are detected and modeled.
Onset of the Magnetic Explosion in Solar Polar Coronal X-Ray Jets
Authors: Moore Ronald L. , Sterling Alphonse C. , Panesar Navdeep K.
Published: May 2018

We follow up on the Sterling et al. discovery that nearly all polar coronal X-ray jets are made by an explosive eruption of a closed magnetic field carrying a miniature filament in its core. In the same X-ray and EUV movies used by Sterling et al., we examine the onset and growth of the driving magnetic explosion in 15 of the 20 jets that they studied. We find evidence that (1) in a large majority of polar X-ray jets, the runaway internal/tether-cutting reconnection under the erupting minifilament flux rope starts after both the minifilament’s rise and the spire-producing external/breakout reconnection have started; and (2) in a large minority, (a) before the eruption starts, there is a current sheet between the explosive closed field and the ambient open field, and (b) the eruption starts with breakout reconnection at that current sheet. The variety of event sequences in the eruptions supports the idea that the magnetic explosions that make polar X-ray jets work the same way as the much larger magnetic explosions that make a flare and coronal mass ejection (CME). That idea and recent observations indicating that magnetic flux cancellation is the fundamental process that builds the field in and around the pre-jet minifilament and triggers that field’s jet-driving explosion together suggest that flux cancellation inside the magnetic arcade that explodes in a flare/CME eruption is usually the fundamental process that builds the explosive field in the core of the arcade and triggers that field’s explosion.
Precision Scaling Relations for Disk Galaxies in the Local Universe
Authors: Lapi A. , Salucci P. , Danese L.
Published: May 2018

We build templates of rotation curves as a function of the I-band luminosity via the mass modeling (by the sum of a thin exponential disk and a cored halo profile) of suitably normalized, stacked data from wide samples of local spiral galaxies. We then exploit such templates to determine fundamental stellar and halo properties for a sample of about 550 local disk-dominated galaxies with high-quality measurements of the optical radius R
opt and of the corresponding rotation velocity V
opt. Specifically, we determine the stellar M
⋆ and halo M
H masses, the halo size R
H and velocity scale V
H, and the specific angular momenta of the stellar j
⋆ and dark matter j
H components. We derive global scaling relationships involving such stellar and halo properties both for the individual galaxies in our sample and for their mean within bins; the latter are found to be in pleasing agreement with previous determinations by independent methods (e.g., abundance matching techniques, weak-lensing observations, and individual rotation curve modeling). Remarkably, the size of our sample and the robustness of our statistical approach allow us to attain an unprecedented level of precision over an extended range of mass and velocity scales, with 1σ dispersion around the mean relationships of less than 0.1 dex. We thus set new standard local relationships that must be reproduced by detailed physical models, which offer a basis for improving the subgrid recipes in numerical simulations, that provide a benchmark to gauge independent observations and check for systematics, and that constitute a basic step toward the future exploitation of the spiral galaxy population as a cosmological probe.
Herschel PACS Observations of 4–10 Myr Old Classical T Tauri Stars in Orion OB1
Authors: Maucó Karina , Briceño César , Calvet Nuria , Hernández Jesús , Ballesteros-Paredes Javier , González Omaira , C. Espaillat Catherine , Li Dan , Telesco Charles M. , Downes Juan José , Macías Enrique , Qi Chunhua , Michel Raúl , D’Alessio Paola , Ali Babar
Published: May 2018

We present Herschel PACS observations of eight classical T Tauri Stars in the ∼7–10 Myr old OB1a and the ∼4–5 Myr old OB1b Orion subassociations. Detailed modeling of the broadband spectral energy distributions, particularly the strong silicate emission at 10 μm, shows that these objects are (pre-)transitional disks with some amount of small optically thin dust inside their cavities, ranging from ∼4 to ∼90 au in size. We analyzed Spitzer IRS spectra for two objects in the sample: CVSO-107 and CVSO-109. The IRS spectrum of CVSO-107 indicates the presence of crystalline material inside its gap, while the silicate feature of CVSO-109 is characterized by a pristine profile produced by amorphous silicates; the mechanisms creating the optically thin dust seem to depend on disk local conditions. Using millimeter photometry, we estimated dust disk masses for CVSO-107 and CVSO-109 lower than the minimum mass of solids needed to form the planets in our solar system, which suggests that giant planet formation should be over in these disks. We speculate that the presence and maintenance of optically thick material in the inner regions of these pre-transitional disks might point to low-mass planet formation.
Ethmia iranella Zerny, 1940 – a Spanish enigma (Lepidoptera, Ethmiidae)
Authors: Sattler Klaus
Published: May 2018

Attention is called to the presence of Ethmiairanella in Spain and its occurrence in Italy is recorded for the first time.
Coccomyxa antarctica sp. nov. from the Antarctic lichen Usnea aurantiacoatra
Authors: Cao Shunan , Zhang Fang , Zheng Hongyuan , Liu Chuanpeng , Peng Fang , Zhou Qiming
Published: May 2018

The single celled green alga Coccomyxaantarctica Shunan Cao & Qiming Zhou, sp. nov. was isolated from the Antarctic torrential lichen Usneaaurantiacoatra (Jacq.) Bory. It is described and illustrated based on a comprehensive study of its morphology, ultrastructure, ecology and phylogeny. C.antarctica is a lichenicolous alga which has elongated cells and contains a parietal chloroplast as observed under the microscope. C.antarctica is clearly different from other species by phylogenetic analysis (ITS rDNA and SSU rDNA sequences), also it differs from its phylogenetic closely species C.viridis by its larger cell size.
Entreprises religieuses transnationales en Afrique de l'Ouest
Authors: Bava Sophie
Published: May 2018

Le Niger est une plaque tournante qui permet de comprendre comment se construisent les itinéraires religieux des migrants sénégalais entre le pays de départ et le pays d’immigration. Cette contribution souligne l’importance des réseaux mourides comme espaces cultuels et culturels mais également comme espace de solidarité pour les jeunes en transit. Les espaces religieux, dahira mouride notamment et autres zawiya-s , constituent des lieux ressources pour les candidats à l’immigration, mais également des lieux de confrontation et de reconfiguration de l’Islam mouride dans cette région.
Entreprises religieuses transnationales en Afrique de l'Ouest
Authors: Laurent Pierre-Joseph
Published: May 2018

L’Église des Assemblées de Dieu du Burkina Faso, qui représente 5 % de la population nationale, et près de 90 % de la mouvance pentecôtiste du pays, occupe une situation unique en Afrique de l’Ouest. Cette Église historique implantée dès 1921 a joué un rôle important dans le paysage religieux et politique du pays et dans la diffusion de l’Œuvre dans les pays limitrophes. Elle a exercé aussi une certaine ascendance sur les Églises sœurs de la région même si d’autres Églises ont aujourd’hui pris le relais. Ce texte met l’accent sur les principaux aspects liés à l’organisation du travail missionnaire. Il décrit plus particulièrement la fonction de pionnier tenu, seul ou en qualité d’auxiliaire, par quelques pasteurs burkinabé, ensuite le travail des pasteurs missionnaires du Burkina Faso et enfin de la VIMAB (la Vision Missionnaire des Assemblées de Dieu du Burkina Faso).
Entreprises religieuses transnationales en Afrique de l'Ouest
Authors: Fancello Sandra
Published: May 2018

L’Église ghanéenne The Church of Pentecost est travaillée par une série de débats et controverses concernant la distribution de l’autorité notamment dans ses rapports aux autres communautés africaines. Son expansion a trouvé des relais dans la collaboration avec les pasteurs togolais d’abord, puis ivoiriens. Au Ghana, le débat que soulève la formation d’assemblées en français et en anglais porte sur le statut de ces assemblées au sein d’une Église qui se pense à la fois « indigène » et transnationale. Un autre débat très important concerne le statut des camps de prière constitués en véritables institutions au sein même de l’Église qui peine à les soumettre à son autorité. Ces débats sont à l’origine de plusieurs dissidences, au Ghana comme en Côte-d’Ivoire.