bluuebunny/crossref_metadata_2025 huggingface dataset:
Previsão de demanda: simulação em uma empresa do segmento de artigos para dança, fitness, natação e sportswear
Authors: Candeias Tamires Mazaro , Olivo Andréia de Menezes , Lemos Felipe Kesrouani
Published: March 2020

A indústria de moda esportiva demonstra ser um mercado promissor com um grande potencial de crescimento. Neste sentido, este trabalho tem como objetivo identificar o método de previsão de demanda mais adequado as famílias de produtos de uma empresa do segmento de artigos para dança, fitness, natação e sportswear. O estudo considerou a Média Simples, Média Móvel, Suavização Exponencial, Suavização Exponencial com Tendência – Método de Holt e Suavização Exponencial com Tendência e Sazonalidade – Método de Holt-Winters, para simulação da previsão de demanda, por meio de planilhas eletrônicas com auxílio de codificação em linguagem VBA. Os resultados mostram que as previsões apresentaram o menor erro absoluto percentual médio (MAPE) por meio da simulação em Suavização Exponencial com Tendência e Sazonalidade - Método de Holt-Winters, devido sua maior sensibilidade as características da demanda, sendo o segundo melhor método observado na maioria das famílias de produtos a Suavização Exponencial com Tendência - Método de Holt e a Média Simples o método que apresentou os piores índices de previsão, com grande percentual de erro.
An analysis of the times of stoppages of equipments in a food industry: a case study
Authors: Pandolfi Marcos Alberto Claudio , Komninakis Denis , Piratelli Claudio Luis , Costa Vera Mariza Henriques de Miranda , Achcar Jorge Alberto
Published: March 2020

The main objective of this study is to analyze the data related to the times of stoppages of equipment due to several causes in a food industry in the fruit sector located in São Paulo State, Brazil. Several causes can affect the performance of such equipment as the industry sector where the equipment is used, the type of equipment, the period of operation and the harvest (year).The results of this analysis could be of great interest to managers of industry in terms of better planning on the use of machinery, detection of the risk factors for the use of machinery and minimization of maintenance shutdowns.
Editorial: Off the radar so far: The conservation of scientific collections and heritage
Authors: Lourenço Marta C.
Published: March 2020

As far as I know, this is the first volume dedicated to scientific collections in a conservation journal, something I have to thank to the previous director of Conservar Património, António João Cruz, and the current director, Elin Figueiredo. The fact that there are only four articles does not mean that the problem is uncommon or uninteresting, but only that we are in its infancy. I hope that these four articles will open up new perspectives of conservation research or at least awaken the curiosity of conservator-restorers, especially those currently in training.
Integrasi Program Pencegahan HIV/AIDS melalui Transmisi Seksual ke dalam Sistim Kesehatan di Kota Kupang
Authors: Sir Amelya Betsalonia
Published: March 2020

Background: HIV and AIDS prevention efforts in Indonesia could not be denied that it is still influenced by global health initiatives. As global initiatives continue to decline, efforts to integrate HIV and AIDS programs into the framework of the national health system are both challenges and hopes for achieving program effectiveness and sustainability. This study aims to explore how far the integration of HIV transmission program through sexual transmission into the health system contributes to the effectiveness of programs at the Kupang City level. Method: The method used in this research is qualitative analysis with case study design as an effort to understand more deeply the relationship between the integration and effectiveness of AIDS prevention program. In this study the 'case' chosen was HIV prevention programs through sexual transmission for Female Sex Workers. Results: The results of the study showed that in the prevention of HIV transmission programs through sexual transmission as many as five sub-systems of health were partially integrated, including sub-systems of management and regulation, health financing, human resource management, provision of pharmaceuticals and medical devices and sub-systems for community participation management, while the strategic information sub sub-system is not integrated in the health system. The integration of some sub-systems into the health system does not contribute to the effectiveness of the program. Therefore, it was necessary to strengthen each sub-systim, especially in regions ranging from regulation, planning and budget including human resources to increase regional independence and not rely on foreign funds for the implementation of HIV prevention programs through sexual transmission, besides that it also increases collaboration with stakeholders.
Analisis Faktor Risiko Kejadian Diabetes Mellitus Tipe II di Wilayah Pedesaan
Authors: Wijayanti Siwi Pramatama Mars , Nurbaiti Tias Tri , Maqfiroch Arrum Firda Ayu
Published: March 2020

Background: Diabetes mellitus (DM) is a non-communicable disease that remains a significant health concern in Indonesia. The disease is more prevalent in urban areas due to lifestyles, socioeconomics level and lack of physical activity. Currently, DM has begun occured also in rural areas. The purpose of this study is to identify the risk factors associated with Type II DM incidence in rural areas.Method: This is analytical study with a case-control design, located in Community Health Centre 1, Wangon, Banyumas Regency. There are 65 people in case group and 65 people in control group involved in this study. Variables included personal characteristics, dietary habit, physical activity and exposure to cigarette smoke. Data was obtained by structured questionnaire and analyze using univariate, bivariate (chi-square test) and multivariate analysis (logistic regression test).Results: The results showed that the dietary habit (OR = 11,824; 95% CI = 4,988-28,032) and physical activity (OR = 2,608; 95% CI = 1,116–6,095) had influenced on the incidence of DM type II. Whilst the exposure of cigarette smoking did not influenced the incidence of DM type II. It is suggested that consume foods with balanced nutrition and doing physical activities should be conducted routinely in accordance with WHO recommendations.
Perempuan dan IMS : Perilaku Menjaga Personal Hygiene Organ Reproduksi pada Pekerja Seks Langsung di Indonesia
Authors: Rokhmah Dewi , Nurwidyansyah Shinta Dwi , Rif'ah Erwin Nur
Published: March 2020

Background: The localization of prostitution in Jember District has been closed permanently since 2007. It causes the hidden prostitution business that has been increasing in the street or as indirect sex work. This condition makes the limited access to provide information, condoms and STDs screening among female sex workers (FSWs).  Besides using condom, washing reproductive organs are often conducted to prevent STDs. This study aims to explore the behavior of FSWs in washing and lubricating reproductive organs. Method: This is a qualitative research which involved 12 FSWs in three areas of ex-localization in South Jember, 5 pims and health staffs. Data were collected through indepth-interviews and observation of work areas. Thematic content analysis was employed to identify themes and patterns of data.  Results: The behavior of genital hygiene among FSWs to keep healthy was relatively categorized not good. Beside low consistent in condom use, most of them wash their vagina using traditional herbs or soap. They also often drink traditional herbs to prevent STDs. Lack of knowledge and support from the pimps and health staffs to use condom during sex made them vulnerable from STDs. Changing panties routinely and avoid anal sex were practiced among FSWs to have safe sex.
Kemitraan Puskesmas dan Sekolah dalam Pencegahan Malaria pada Anak Usia Sekolah di Seluma Bengkulu
Authors: Novrinda Hilza , Misnaniarti Misnaniarti , Flora Rostika , Zulkarnain HM , Samwilson Samwilson , Tanjung Risnawati
Published: March 2020

Background: The partnership between Puskesmas (Community Health Center) and school to improve the health of school-age children known as the Trias school health unit. In Seluma only 7.69% of schools have a room for health school program. This study aims to explore the partnership between Puskesmas’ and schools in malaria prevention to school-age children in Seluma. Method: This study used qualitative research with phenomenological approach. It was conducted in April 2019. The main informants consisted of 5 teachers, from 5 elementary schools and 2 UKS staff Puskesmas from Puskesmas Puguk and Puskesmas Talang Tinggi, who have worked over than three years. The data collected by indepth interview, FGDs and observation. Results: The role of the UKS Puskesmas staffs was not optimal in carrying out the triad UKS activities. They only carry out routine UKS activities. Partnership between Puskesmas and schools has not been implemented optimally. It is still very limited action to cooperate the routine triad implementation from the Puskesmas and schools. A review needs to be done to assess the performance of the UKS, especially through healthy school competition activities.
KIM EOK’S TRANSLATION AND HAN YONG-UN’S THE LOVER’S SILENCE – THE INTERIORITY IN THE 1920s’ LITERATURE
Authors: Yang Soon-Mo
Published: March 2020

The article tries to examine and define the inner self of literature in the 1920s, now considered the birth of modern Korean literature. The interiority of 1920’s literature is widely accepted as the transition period between the birth (the 1910s, the Enlightenment) and maturation (1930s, Modernism), and as a reflection of the tragic situation after 1919. However, in the light of the symptom that determines the structure of desire, the inner self of 1920’s literature could be identified as a “person who denies loss”, a pervasive attitude. And it also could provide a critical reading along with some directivity, which is meaningful to concepts such as self-relation and the other relations that construct the individual. This paper examines this perspective of inner self within 1920’s literature of Kim Eok and Han Yong-un, so as to set an intrinsic standard that would enable scholars to evaluate the literary value of the 1920’s. Above all, through the Symptomatic Identification approach, this study will conduct archeological and genealogical research that could be helpful to today’s discourse.
La prevalencia entre: protección de derechos fundamentales o elementos de la naturaleza del cargo
Authors: Moreno González Fernando , Arévalo Sanabria Lina
Published: March 2020

Este artículo, pretende esclarecer los lineamientos jurisprudenciales en torno a la estabilidad laboral reforzada de los servidores públicos provisionales y de los de libre nombramiento y remoción, determinando así, los criterios para su amparo y el alcance del mismo, sin perjuicio de los elementos naturales de su nombramiento. De esta forma, se logró determinar que, en caso de los provisionales, son cobijados extensivamente pese la transitoriedad de su vinculación, caso contrario, ocurre con los servidores de libre nombramiento y remoción, los cuales, el amparo a sus derechos fundamentales es excepcionalísimo, aunque se encuentre inmerso el riesgo de vulneración de los mismos.
LOS MECANISMOS DE REPARACIÓN A VÍCTIMAS Y SU INCIDENCIA EN LA RESTITUCIÓN DE TIERRAS EN COLOMBIA
Authors: Buitrago Valderrama William
Published: March 2020

El siguiente trabajo de investigación, tiene como objetivo principal hacer un estudio sobre cuáles son los derechos de las víctimas del conflicto armado en Colombia y el papel que ha desarrollado el Estado colombiano en la restitución de tierras, teniendo en cuenta que son sujetos de especial protección legal y constitucional, siendo conscientes que el conflicto interno ha surgido como un intento de cambiar los ideales políticos, sociales y económicos del país. De igual manera, la disertación se centrará en el papel que debe tener el Estado colombiano de asegura los derechos, a la verdad a la justicias y a la reparación garantizando una vida digna dentro del Estado Social de Derecho, siendo este el encargado de velar por el cumplimiento de todos los parámetros y mecanismos necesarios para la protección de los derechos que están legalmente positivizados en la Constitución.
Sanción moratoria por consignación inoportuna de cesantías a servidores públicos: jurisdicción competente y derechos fundamentales
Authors: Figueroa Salamanca Oscar
Published: March 2020

Ha sido una constante la incertidumbre en la jurisdicción competente para tramitar y decidir los procesos que versan sobre el pago de la indemnización moratoria por consignación tardía de cesantías a servidores públicos. Partiendo de un estudio conciso sobre el alcance de las tesis jurisprudenciales edificadas al respecto, y paralelamente, de sus ambigüedades, matices y efectos en los procesos instruidos por despachos laborales y contencioso administrativos de nuestro país, el autor asevera y explica por qué la ausencia de uniformidad y coherencia en cuanto a la vía procesal de solución de estas controversias constituye una trasgresión a los derechos constitucionales fundamentales al debido proceso, igualdad, acceso a la administración de justicia y a los principios de confianza legítima y seguridad jurídica. En la parte final, se enaltece la reciente adopción de un criterio más o menos unívoco como garantía de verdadero respeto al precedente judicial, aunque se llama a la prudencia frente a la aplicación sorpresiva de cambios jurisprudenciales a procesos ejecutivos en curso.
La actualidad del concepto de sobrenaturaleza de José Ortega y Gasset: una mirada desde la inteligencia artificial
Authors: Terrones Rodríguez Antonio Luis
Published: March 2020

Los primeros textos en los que José Ortega y Gasset reflexionaba sobre la técnica se publicaron en 1935. Ha pasado casi un siglo y este texto pretende rescatar uno de los conceptos que el filósofo español presentó en Meditación de la técnica, a saber, la sobrenaturaleza. En la actualidad, el gran reto que la tecnología se ha impuesto ha sido el de llevar a su máximo exponente a la inteligencia artificial, para hacerla un medio desafiante de los límites que nos impone la naturaleza. Entre las propuestas más destacadas dentro del campo de los sistemas artificiales se encuentra la superinteligencia y la singularidad, dos de los deseos más anhelados por pensadores como Nick Bostrom o Raymond Kurzweil. Así pues, si el campo tecnológico está centrando grandes esfuerzos en el desarrollo de la inteligencia artificial, deberíamos preguntarnos si la motivación que se encuentra detrás de tal impulso se fundamenta verdaderamente en la necesidad humana de una sobrenaturaleza de la que tanto nos hablaba Ortega y Gasset.
Ensayo “machirulo”. Hacia la comunicación del vínculo, del cuidado y de los afectos
Authors: Rincón Rodríguez Ómar
Published: March 2020

En este ensayo “machirulo” —mansplaining, intentando ser discursivamente correcto—, se parte de la vitalidad política, cultural y comunicativa del movimiento feminista como propuesta de que otro mundo-economía-sociedad-cultura es posible, para luego reparar en que se debe intentar hacer una comunicación feminista desde lo narrativo, la estética y los formatos, y termina con la perplejidad de cómo hacer posible un feminismo en perspectiva de les jóvenes.
Persistencia y regionalización del desplazamiento forzado en Colombia (2005-2010; 2011-2016): una aproximación desde el análisis espacial
Authors: Navarrete Suárez Joahana
Published: March 2020

El presente documento analiza el fenómeno del desplazamiento forzado durante dos periodos: 2005-2010 y 2011-2016; este último se encuentra entre el inicio de las conversaciones que antecedieron el pacto de paz con las FARC y la modificación de políticas y programas para el combate del narcotráfico en los municipios con mayor presencia de conflicto y grupos armados ilegales (4 de septiembre de 2012 y 26 de septiembre de 2016). La investigación tiene como objetivo dar cuenta de la distribución y la concentración del desplazamiento forzado, evidenciar la persistencia de este fenómeno en los periodos establecidos, y evaluar los determinantes del fenómeno en los municipios donde se presenta. A través del uso de métodos que evalúan la dependencia espacial y evalúan la existencia de regímenes espaciales se encontró que la distribución del desplazamiento no está dada aleatoriamente en el espacio, se comprueba que el largo plazo de los periodos de análisis las proporciones de desplazamiento tiene una autocorrelación espacial positiva que muestra los rasgos de persistencia y difusión.
Mercosur y la visión estratégica regional brasileña
Authors: Arévalo Parra Juan Camilo
Published: March 2020

A través de una metodología cualitativo, este estudio busca demostrar la siguiente hipótesis: el Mercosur, y su relanzamiento bajo Lula da Silva (2003-2010), plasmó una visión estratégica de Brasil, que se venía consolidando antes de los dos mandatos de este presidente, que buscaba que este proyecto integracionista multidimensional se volviese una herramienta crucial para el fortalecimiento de un bloque suramericano liderado por este país. Con esto se quería contribuir al desarrollo de la región, y al posicionamiento del Cono Sur como una voz decisiva en la política internacional
El emprendimiento en la mujer rural del siglo XXI
Authors: Antúnez Sánchez Alcides
Published: March 2020

El emprendimiento se ha posicionado al interior de las universidades como un tema importante, por considerar que la formación disciplinar no es suficiente para desempeñarse exitosamente en el mundo actual: es necesario, además, formar capacidades y ofrecer alternativas de vida para los futuros profesionales con competencias en el siglo xxi. Los gobiernos también han vinculado el emprendimiento dentro de sus agendas y han estructurado planes, programas y proyectos para fortalecerlo, entendiendo que su promoción puede contribuir al desarrollo económico y social de los países. En este sentido, como parte de esta política se han regulado cuerpos jurídicos dentro de los ordenamientos jurídicos, como política de fomento hacia una cultura del emprendimiento. El ensayo tiene como objetivo demostrar la necesidad de fomentar políticas públicas que tributen al emprendimiento en las universidades de América Latina, para entregar un profesional con competencias para el desarrollo rural en su incursión en el rol de empresarias.
Subpopulation of Immigrants in Lithuania: Foreign-Born Generations
Authors: Stankūnienė Vladislava , Ambrozaitienė Dalia , Baublytė Marė
Published: March 2020

The article analyzes the foreign-born population of Lithuania, its age and ethnic composition, and periods of arrival to Lithuania. The analysis is based on the 2011 Lithuanian Population Census data. The results of the analysis show that the foreign-born population of Lithuania is very heterogeneous and has three major groups formed at different times, by different immigration factors and flows, they are different by age and ethnic composition. Most of foreign-born population of Lithuania is formed during the Soviet era - those who arrived from the former USSR. Among them the majority are of Russians, but a quite large part - Lithuanians who arrived since the mid-sixties of 20th century (children of deportees). The youngest generation of the emerging foreign-born generation is from Western European countries.
Testing Linear and Nonlinear Hypotheses in a Cox Proportional Hazards Model with Errors in Covariates
Authors: Chernova Oksana , Kukush Alexander
Published: March 2020

We investigate linear and nonlinear hypotheses testing in a Cox proportional hazards model for right-censored survival data when the covariates are subject to measurement errors. In Kukush and Chernova (2018) [Theor. Probability and Math. Statist. 96, 101–110], a consistent simultaneous estimator is introduced for the baseline hazard rate and the vector of regression parameters. Therein the baseline hazard rate belongs to an unbounded set of nonnegative Lipschitz functions, with fixed constant, and the vector of regression parameters belongs to a compact parameter set. Based on the estimator, we develop two procedures to test nonlinear and linear hypotheses about the vector of regression parameters: Wald-type and score-type tests. The latter is based on an unbiased estimating equation. The consistency of the tests is shown.
Efecto de una intervención de soporte social en cuidadores de personas con enfermedad crónica
Authors: Chaparro Diaz Lorena , Carreño Moreno Sonia Patricia , Carrillo Gonzalez Gloria Mabel , Gómez Ramirez Olga Janneth
Published: March 2020

Objetivo: determinar el efecto de la intervención de enfermería “Alguien apoya al que cuida” sobre las percepciones de soporte social y de sobrecarga con el cuidado de cuidadores familiares de personas con enfermedad crónica.Metodología: estudio de tipo cuantitativo cuasiexperimental con un grupo experimental y de control, al que se le realizó medición antes y después de la intervención aplicando los instrumentos de soporte social percibido de Sherbourne y Stewart y entrevista de sobrecarga de Zarit en un total de 137 participantes que cumplieron con los criterios de inclusión de ser cuidador principal por más de seis meses y estar vinculado al programa “Cuidando a los Cuidadores®” de la Facultad de Enfermería de la Universidad Nacional de Colombia. Los datos fueron analizados por medio de estadística descriptiva e inferencial no paramétrica en la que se aplicó la prueba de Mann-Whitney para el análisis intergrupos.Resultados: no existe diferencia significativa entre grupos en las mediciones pre y posprueba en ninguna de las variables, además se presenta un mínimo cambio entre las medias de la variable de sobrecarga entre la pre y la posprueba del grupo experimental.Conclusión: se advierte que el efecto mínimo de la intervención propuesta se presenta por la multidimensionalidad del soporte social, además del uso de otro tipo de TIC diferentes a las propuestas en este estudio.
Varicose veins: on the verge of discovering the cause?
Authors: Zolotukhin Igor A. , Porembskaya Olga Ya. , Smetanina Mariya A. , Sazhin Aleksandr V. , Filipenko Maksim L. , Kirienko Aleksandr I.
Published: March 2020

Varicose veins of the lower limbs are one of the most common and wide-spread pathology all around the world. What triggers the specific changes in a vein wall still remains unclear as well as what happens in the layers of the vein wall after the disease starts. The aim of the article is to analyze published data and results of researches on epidemiology, genetics, cellular and molecular mechanisms underlying varicose veins pathogenesis. It is now commonly accepted that vein wall changes in patients with varicose veins result from vein-specific inflammation. This process includes leukocytes adhesion to venous endothelium with their subsequent migration into the vein wall and surrounding tissues. Activated leukocytes express a number of molecules that lead to vein wall remodeling and dilation. Comprehensive assessment of the epidemiological data on the prevalence of varicose veins and risk factors, of the findings from genetic studies, of data on molecular-cell interactions as well as results of various surgical interventions in patients with varicose veins, shows that remodeling is a reversible process that can be stopped and reversed by different stimuli including some chemical substances. For the first time in the literature, the authors assume that varicose veins can be successfully cured pharmacologically with no surgical interventions needed.
The pathomorphosis of inflammatory bowel diseases
Authors: Maev Igor V. , Shelygin Yurii A. , Skalinskaya Maria I. , Veselov Alexey V. , Skazyvaeva Ekaterina V. , Rasmagina Irina A. , Komarova Diana A. , Bakulin Igor G.
Published: March 2020

Inflammatory bowel diseases (IBD) are immune-mediated diseases and usually manifest at a young age. They are requires in a long-term treatment or surgery with a high probability of surgical intervention. IBDs are accompanied by a decrease in working capacity, impaired quality of life and social disadaptation. However, timely diagnosis with using modern diagnostic methods, the use of evidence-based immunosuppressive and biological therapy significantly changed the pathomorphosis of this disease. But despite the achievements of the pharmacotherapy, the incidence and prevalence of IBD are still increasing, a demand for surgery remains both for Crohn`s disease and ulcerative colitis throughout all the period of illness. At the same time there is a trend towards the variability of symptoms, mismatch of the clinical symptoms with the real severity of inflammation, increase of a number of patients with extraintestinal manifestations and resistance to induction and maintenance therapies. In addition to this, the observation of this group of patients is complicated due to the difficulty of the early diagnosis and differential analysis of IBD, the need of early induction treatment according to the guidelines and the lack of adherence to the therapy.
Gastric Neuroendocrine Neoplasias: Literature Review
Authors: Mikhaleva Liudmila M. , Vasyukova Olesya A. , Birukov Andrey E. , Guschin Mikhail Yu. , Midiber Konstantin Yu. , Akopyan Emma P. , Khovanskaya Tatyana N.
Published: March 2020

A brief retrospective journey into the history of neouroendocrine neoplasias serves to remind the histology and distribution of neuroendocrine cells in the gastric mucosa, followed by chronological review of NEN discovery and theory development up to the present moment. The morphological classification of gastric NET consisting of 4 possible types is highlighted: the correct interpretation of the pathological findings, taking into account not only the histological features of the tumor itself, but also of the adjacent mucosa, allows to suggest the appropriate managment, which fundamentally affects patient survival.

The review provides other current classifications of the gastric neuroendocrine neoplasia depending on its location, embryogenesis, functional activity, histological grade (with a focus on the Ki-67 labeling index counting, and ways to improve the interobserver reliability in routine practice). Moreover, the differences in the gastric NET and NEC TNM classification are emphasized. The drawbacks of all classifications are discussed and the possibilities for their further development are considered. An important part of the review is the description of a possible immunohistochemical markers, since immunohistochemistry is widely used to confirm the diagnosis. In addition, INSM1 (insulinomaassociatedprotein 1), the new immunohistochemical and molecular marker for NEN is discussed: according to the literature, it contributes to more accurate assessment of the tumor malignant potential and the metastatic risk.

Furthermore, modern methods of endoscopic and PET/CT imaging (68-gallium DOTATATE PET/CT, molecular imaging using SSTR (somatostatin receptor) PET/CT or GLP-1R (Glucagon-like peptide-1 receptor) SPECT (single photon emission computed tomography)/CT), which allows the clinician to suspect a NEN even before morphological analysis of the resected specimen and adequately select the extent of surgical intervention are shown.

In conclusion, we would like to reiterate the importance of further research on the gastric NET subtype pathogenesis and their clinical behavior, also of the correlation of the endoscopic, morphological, and immunohistochemical picture with the patient prognosis to improve managment tactics.
Behaviour of buckling-restrained brace equipped with steel and polyamide casing
Authors: Gholhaki Majid , Pachideh Ghasem , Lashkari Rahim , Rezayfar Omid
Published: March 2020

Steel bracings are one of the most widely used systems for resisting transverse loads in the design and retrofit of concrete and steel structures. This paper reports on an experimental and numerical study of the effects of core steel and the distance of the core from the casing on the behaviour of buckling-restrained braces. Laboratory models of six braces with a core made from conventional ST37 steel or ST37-n steel (softened at a temperature of 1000° using the O'Neill method) with a core–casing distance of 0, 2 or 3 mm were designed. The experimental results showed that, compared with the brace made from ST37 steel, the use of ST37-n steel resulted in a reduction of 32% in the tensile and compressive strengths of the brace. An increase in the core–casing distance in the ST37 and ST37-n braces resulted in reductions in the brace bearing capacity and energy dissipation by 26% and 52%, respectively. An increase in the core–casing distance to more than 2 mm resulted in loss of symmetry and stability of the hysteresis behaviour of the brace; in addition, distortion due to brace local buckling under pressure also intensified.
El Centro Psicológico Salesiano "Dr. P. Emilio Gambirasio". Trayectoria y perspectivas
Authors: Morán García Eduardo
Published: March 2020

El Centro Psicológico Salesiano "Dr. P. Emilio Gambirasio". Trayectoria y perspectivas
El Documento de Aparecida: una visión de conjunto
Authors: Brighenti Agenor
Published: March 2020

Con el objetivo de ayudar al lector a entender mejor el Documento de Aparecida, es importante dar una visión en conjunto del texto. Se debe tener presente los grandes ejes o temas transversales del mismo. Son éstos los que dan homogeneidad al contenido, haciendo de él un todo, si no armónico, por lo menos lógico.
Claves bíblicas del Documento de Aparecida
Authors: Guerra Carrasco José
Published: March 2020

El Documento de Aparecida ha tenido el tiempo suficiente para adentrarse en el corazón de los creyentes. Es hora de evaluar sus desafíos pastorales. En este artículo trataremos de analizar los principales elementos bíblicos que iluminan esta hoja de ruta de la Iglesia latinoamericana y caribeña en el próximo decenio.
Aspectos sociopolíticos de Aparecida
Authors: Henriquez Alberto
Published: March 2020

Hace tres años la Quinta Conferencia General del Episcopado Latinoamericano y de El Caribe emitió un Documento Conclusivo, que resumía las principales posiciones de los diversos representantes de la Iglesia latinoamericana de cara al futuro del catolicismo en nuestras tierras. Reconociendo que es un escrito fruto de la acción del Espíritu Santo en la Historia, sin embargo, no podemos soslayar diversos componentes sociales y políticos que condicionan la orientación de la mencionada publicación.La realidad vista desde una globalidad genérica ...
Claves para la catequesis a la luz de Aparecida
Authors: Coronado Carmita
Published: March 2020

La reflexión acerca de la historia de la catequesis contemporánea requiere que se aborden contextos culturales y eclesiales diferentes, teniendo en cuenta las investigaciones en pedagogía catequética, recordando las orientaciones del Magisterio: Catecismo de la Iglesia Universal, Directorio General para la catequesis, Cathechesis Tradendae, entre otros; donde se enumeren y analicen algunas publicaciones, releyendo enciclopedias y obras de grandes autores actuales.
Human embryonic stem cells differentiation into oligodendrocyte lineage cells v1
Authors: Pooyan Paria , Baharvand Hossein , Javan Mohammad , Hosseini Salekdeh Ghasem
Published: March 2020

Oligodendrocyte (OL) lineage cell generation from human embryonic stem cell line Royan H6 (RH6) started by dual inhibition of SMAD signaling. Therefore, within eight days, adherent NANOG+RH6 cells (B) differentiated into SOX1+ neural stem cells (C). Next, the embryonic ventral spinal cord environment (pMN domain) was mimicked by the application of two morphogens, RA and SAG and the OLIG2+ neural progenitor cells were generated on day 12 (D) of differentiation. Further, oligodendrocyte progenitor cell commitment was achieved on day 20, when the pre-oligodendrocyte progenitor cell (pre-OPC) aggregates were positively stained by NKX2.2+ (E). From day 20 to day 80, supportive reagents for pre-OPCs maturation into PDGFRA+ OPCs (F), and their further expansion and maturation toward oligodendrocyte producing OPCs were added to the culture medium. Finally, on day 80 the growth-factors were withdrawn from the culture medium and OPCs were differentiated into MBP+ OLs (G). References: - Baharvand H, Ashtiani SK, Taee A, Massumi M, Valojerdi MR, Yazdi PE, et al. Generation of new human embryonic stem cell lines with diploid and triploid karyotypes. Dev Growth Differ. 2006;48:117–28. - Douvaras P, Wang J, Zimmer M, Hanchuk S, O’Bara MA, Sadiq S, et al. Efficient generation of myelinating oligodendrocytes from primary progressive multiple sclerosis patients by induced pluripotent stem cells. Stem Cell Reports [Internet]. The Authors; 2014;3:250–9. Available from: http://dx.doi.org/10.1016/j.stemcr.2014.06.012 - Douvaras P, Fossati V. Generation and isolation of oligodendrocyte progenitor cells from human pluripotent stem cells. Nat Protoc [Internet]. 2015;10:1143–54. Available from: http://dx.doi.org/10.1038/nprot.2015.075 - Piao J, Major T, Auyeung G, Policarpio E, Menon J, Droms L, et al. Human embryonic stem cell-derived oligodendrocyte progenitors remyelinate the brain and rescue behavioral deficits following radiation. Cell Stem Cell [Internet]. Elsevier Inc.; 2015;16:198–210. Available from: http://dx.doi.org/10.1016/j.stem.2015.01.004
Forecasting study of mains reliability based on sparse field data and perspective state space models
Authors: Valis David , Forbelská Marie , Vintr Zdeněk
Published: March 2020

The elements of critical infrastructure have to meet demanding dependability, safety and security requirements. The article deals
with the prognosis of water mains reliability while using sparse irregular filed data. The data are sparse because the only thing
we know is the number of mains failures during a given month. Since it is possible to transform the data into a typical reliability
measure (rate of failure occurrence – ROCOF), we can examine the course of this measure development in time. In order to model
and predict the ROCOF development, we suggest novel single and multiple error state space models. The results can be used for
i) optimizing mains operation and maintenance, ii) estimating life cycle cost, and iii) planning crisis management.
The concept of integrating vapor chamber into a housing of electronic devices for increased thermal reliability
Authors: Korta Jakub , Skruch Paweł
Published: March 2020

Systematic increase in computational power and continuous miniaturization of automotive electronic controllers pose a challenge
to maintaining allowable temperature of semiconductor components, preventing premature wear-out or, in extreme cases, unacceptable shutdown of these devices. For these reasons, efficient and durable cooling systems are gaining importance in modern
car technology design, showing critical influence on reliability of vehicle electronics. Vapor chambers (flat heat pipes) which
could support heat management of automotive electronic controllers in the nearest future are passive devices, which transport heat
through evaporation-condensation process of a working liquid. At present, vapor chambers are not commercially used in cooling
systems of automotive controllers, being a subject of research and development endeavors aimed at understanding their influence
on thermomechanical reliability of semiconductor devices used in cars. This paper presents a concept of an electronic controller
aluminum housing integrated with a vapor chamber. The conceptual design was numerically validated in elevated temperature,
typical for automotive ambient conditions. The paper discusses influence of the vapor chamber-based cooling system on the controller’s thermal performance, as well as on its reliability, expressed as the expected lifetime of the device.
Do obstetric anesthesia methods have an impact on gastrointestinal system function in preterm infants?
Authors: ÇAKIR Ufuk , YİLDİZ Duran , KAHVECİOGLU Dilek , OKULU Emel , ALAN Serdar , ERDEVE Omer , ARSAN Saadet , ATASAY Begum
Published: March 2020

Purpose: The reason for gastrointestinal system (GIS) motility problems in premature infants is multifactorial and intestinal immaturity is the most important contributing factor. To investigate the effect of epidural (EA) or general anesthesia (GA) on GIS function and early neonatal morbidity in preterm infants delivered by cesarean section (CS).Materials and Methods: This study was conducted in a single neonatal intensive care unit (NICU) between October 2011 and April 2015. Preterms ≤32 weeks and ≤1500g who were delivered by CS were enrolled in this study. Mode of anesthesia, demographic, clinical characteristics, first meconium passage time, meconium obstruction, use of drug for dysmotility and other preterm morbidities were evaluated. Results: Three hundred and sixty four preterm infants were enrolled during the study period. Use of drug for dysmotility, time to first meconium passage, and meconium obstruction rate, were significantly higher in the GA group. Conclusion: This was the first study in the literature that investigated the role of anesthesia methods, effect on preterm infant GIS motility. Anesthesia modalities during delivery may have an effect on GIS function in preterm infants.
Complement C2 polymorphisms in children with Henoch Schönlein purpura
Authors: KİSLA EKİNCİ Rabia Miray , BALCİ Sibel , ATMİS Bahriye , KARABAY BAYAZİT Aysun , DOGRUEL Dilek , ALTİNTAS Derya Ufuk , BİSGİN Atil
Published: March 2020

Purpose: The aim of this study was to investigate whether C2 polymorphisms influence the symptoms and disease outcomes in children with Henoch Schönlein purpura (HSP).Materials and Methods: This cross-sectional study included 49 children with HSP, diagnosed and followed for at least 6 months in our department between July 2016 and March 2018. Sanger sequencing was performed for detecting C2 gene polymorphisms. Statistical analysis was performed for comparison of clinical and laboratory parameters between patients according to having C2 polymorphisms.Results: Only 6 patients (12.2%) had following C2 gene polymorphisms: rs9332739 (n=3), rs36221133 (n=2), rs146054348 (n=1). Age at disease onset, gastrointestinal and joint involvement, serum complement levels, renal involvement, requirement of systemic steroids and disease relapse were found similar between the patients with and without C2 gene polymorphism. We found higher serum IgM level and lower leukocyte counts in HSP patients with confirmed C2 polymorphisms than the patients with normal C2 gene.Conclusion: Although C2 gene polymorphisms were not related to clinical manifestations and disease outcome in children with HSP, we speculate that C2 gene polymorphisms may be associated with elevated serum IgM levels in patients with HSP.
Can serial measurements of fetal abdominal circumference in the second trimester predict small for gestational age and late fetal-growth restrictions?
Authors: ERASLAN ŞAHİN Mefkure , COL MADENDAG İlknur
Published: March 2020

Purpose: The aim of the present study was to evaluate whether serial measurements of the ultrasonographic abdominal circumference of the fetus in the second trimester is a predictor for a fetus that is small for gestational age and for late fetal–growth restrictions.Materials and Methods: Of the 440 pregnant women were analyzed retrospectively, 200 were in the small for gestational age group, 40 were in the late fetal–growth restrictions group, and 200 were in the healthy control group. For screening fetal growth, ultrasound scans were performed at 18±2, 22±2, and 26±2 weeks of gestation and fetal biometric results were compared among groups.Results: The maternal age, body mass index, nulliparity, and rates of previous cesarean deliveries were similar among the groups. Gestational age at delivery, rates of induced delivery and fetal birth weight were significantly different among the groups. The abdominal circumference diameter at 18, 22, and 26 weeks were similar among the groups; the differences were not significant.Conclusion: Our results suggest that the serial abdominal circumference measurement in the second trimester has a low capacity for predicting small for gestational age and late fetal–growth restrictions in low-risk pregnancies.
Obstrüktif uyku apne sendromlu hastalarda Chalder Yorgunluk Ölçeği'nin Türkçe formunun psikometrik özellikleri
Authors: ÜZER Ahmet , GÜLEÇ Hüseyin
Published: March 2020

Amaç: Bu çalışma obstrüktif uyku apne sendromu (OUAS) kliniğinde önemli bir semptom olan yorgunluğun ölçülmesinin önemli olduğu düşüncesiyle Chalder Yorgunluk Ölçeği (CYÖ)'nin Türkçe versiyonunun geçerlilik ve güvenilirliğini değerlendirmeyi amaçlamıştır.Gereç ve Yöntem: Bu çalışma daha önce hiç tedavi almamış ruhsal veya ek fiziksel hastalığı olmayan 95 OUAS hastalarıyla yapıldı. Toplanan veriler için ölçeğin güvenilirlik analizi madde-toplam korelasyon katsayıları ve Cronbach’ın alfa iç tutarlılık katsayısına bakılırken, geçerlilik analizi için açımlayıcı faktör analizi kullanılarak belirlenmiştir.Bulgular: CYÖ’nün iç tutarlılığı 0.92, madde toplam puan korelasyon katsayıları 0.32 ile 0.83 arasında bulunmuştur. CYÖ’nün örneklem yeterliliğinin açıklayıcı faktör analizi için, Kaiser-Meger-Olkin (KMO) katsayısı ve Bartlett katsayısı sırasıyla 0.89 ve 699.21 olarak bulunmuştur. Tek faktörlü çözüm elde edilmiş, varyansın % 55.8'ini temsil eden 6.13'lük bir özdeğeri bulunmuştur. Ölçek maddelerinin faktör yükleri 0.35 ile 0.88 arasındadır.Sonuç: Çalışmamızda orijinal iki faktörlü yapısı ile uyuşmayan CYÖ’nün tek faktörlü çözümü elde edilmiştir. Türkçe uyarlaması ilk kez mevcut çalışmamızda kullanılan CYÖ'nün Türkçe sürümünün OUAS hastalarında geçerli ve güvenilir olduğu gösterilmiştir.
Effects of combined Pilates and aquaplyometric exercises on postural control and physical functions in patients with multiple sclerosis
Authors: GÜRPINAR Barış , SOYSAL TOMRUK Melda , KARA Bilge , İDİMAN Egemen
Published: March 2020

Purpose: Postural control deficits in people with multiple sclerosis (MS) are common and aggravate in dual tasking. Spinal stabilization approaches like Pilates and aquaplyometric exercises may have a positive effect on postural control. We aimed to determine the effects of combined Pilates and aquaplyometric exercises on postural control with and without dual task and physical functions in people with MS with this study.Materials and Methods: Twelve people with MS were recruited to 8-week combined exercise programme applied twice in a week and evaluated before and after the exercise training. Timed up and go test was performed for functional mobility and Biodex Balance System was used to evaluate the limits of stability (LoS) with and without a cognitive task. Upper limb functions were evaluated with nine-hole peg test (NHPT) and grip strength where 5-Repetition Sit-To-Stand (STS) and timed 25-Foot walk test were used for lower limb functions.Results: Eight-week combined exercise programme improved postural control, upper limb functions and lower limb functions. Additionally, there was no significant difference between LoS tests scores with and without dual task. Conclusion: Eight-week combined aquatic plyometrics and Pilates exercises were effective in improvement of postural control, upper and lower limb functions in people with MS.
Assessing the pros and cons of vaginal birth after caesarean relative to elective repeat caesarean section
Authors: Prasad Sangeeta G. , Malhotra Preeti
Published: March 2020

Background: Recent years have witnessed a rise in rate of primary caesarean section (CS). No. of women reporting with a previous CS scar is also increasing. Judicious trial of labor in such patients can prevent repeat caesarean section. Aim of this study was to assessing the safety and success rate of vaginal birth after caesarean (VBAC) in selected cases of patients who have undergone previous lower segment CS (LSCS) is the main aim of this study.Methods: In this prospective observational study carried out in a tertiary care teaching hospital over a period of 1 year. 375 pregnant women with a history of one previous LSCS for non-recurrent indications were enrolled. The statistical technique of t-test was administered for relative comparison with respect to maternal and neonatal complications across the two groups, i.e. repeat LSCS and vaginal delivery.Results: Out of 375 patients 187 patients (49.9%) underwent elective LSCS for recurrent indication and for non-recurrent indication associated with some complicating factor. Trial of labor in 188 (50.10%) was given out of which 59.3% had spontaneous vaginal delivery,7.20% had instrumental delivery and 33.50% landed into emergency CS. Commonest cause of Em. LSCS being Fetal distress. As regards maternal complications, no statistically significant difference was found between the Repeat LSCS and Vaginal delivery groups (t = 0.779, p > 0.05). On similar lines, there was no statistically significant difference across both groups as regards neonatal complications (t = 0.632, p > 0.05).Conclusions: Taking into account the increased trend of primary CS, trial of VBAC in selected cases is very important. It can be concluded that VBAC has chances of success in cases with previous one LSCS but it must be carefully investigated and monitored.
Comparative study of diclofenac suppository with tramadol suppository in addition to acetaminophen for post caesarian analgesia
Authors: Hooda Reetu , Pathak Prachi , Chavhan Rahul
Published: March 2020

Background: Pain after emergency and elective caesarean section may adversely affect patient’s recovery and breastfeeding initiation. The aim of present study was to compare the analgesic efficacy of diclofenac suppository-intravenous acetaminophen (APAP) combination, tramadol suppository-intravenous APAP combination and intravenous APAP alone for postoperative pain relief after caesarean section.Methods: We designed a randomized double-blind control study. Three hundred parturient scheduled for caesarean section were randomized to receive diclofenac rectal suppository (100 mg), tramadol rectal suppository (100 mg) or glycerin rectal suppository in Group A, B and C respectively (100 parturient in each group). All the women routinely received 1000 mg acetaminophen intravenously. Assessment of pain was done using a visual analogue scale (VAS) at 0, 1, 6, 12, 18 and 24 hours. injection Pentazocine 0.3 mg/kg IV was given as rescue analgesia when VAS score > 30.Results: The mean VAS score was significantly higher in Group C as compared to Group A and Group B (p value < 0.001). This suggests better efficacy of multimodal treatment as compared to monotherapy. Group A as compared to Group B showed better efficacy in term of VAS score at 12 and 18 hours (p = 0.05, p = 0.02 respectively).Conclusions: We found that when controlling for socio-demographic characteristics, combination of either diclofenac or tramadol suppository with acetaminophen has significantly better results when compared with monotherapy of acetaminophen alone in post-operative analgesia after caesarean section. However, the combination of diclofenac suppository has proved to be superior in comparison to tramadol suppository.