bluuebunny/crossref_metadata_2025 huggingface dataset:
Unidad de habitaciones para estudiantes en Ciudad Universitaria, 1952
Authors: Leal-Menegus Alejandro , Escamilla-Pérez Keila
Published: February 2020

En el desarrollo del proyecto de Ciudad Universitaria a principios de la década de 1950 en la Ciudad de México, la vivienda jugó un papel relevante, no obstante, en el campus finalmente construido ésta fue descartada. El presente artículo tiene como objetivo mostrar cómo fue abordado y resuelto el alojamiento para estudiantes al interior del nuevo campus, con la intención de evidenciar los problemas a los que los arquitectos, encargados del proyecto, se confrontaron, y así constatar, si estas cuestiones fueron las responsables del fracaso del proyecto de alojamiento para estudiantes en su conjunto. Para ello, se analiza el proyecto denominado Habitaciones tipo para estudiantes de los arquitectos Enrique Carral Icaza y Manuel Martínez Páez, el cual se complementa con información inédita de archivo. Posteriormente, se compara dicho proyecto con el único edificio construido y aún existente. Este análisis comparativo reveló que el edificio proyectado y la realidad construida no constituyen el mismo edificio y que el papel del arquitecto Jorge L. Medellín fue más relevante de lo que se ha acreditado a la fecha.
Polín de Bambú Ensamblado: diseño alternativo para la construcción de estructuras ligeras
Authors: Soria-López Francisco Javier , Guerrero-Baca Luis Fernando
Published: February 2020

Cada día se vuelve más apremiante la implementación de sistemas de construcción que resulten sostenibles desde el punto de vista económico, ecológico y sociocultural. En esa línea, el aprovechamiento del bambú abre una amplia gama de oportunidades porque existe un desarrollo creciente de la oferta de este producto. El presente texto se centra en un proceso de diseño que aprovecha tallos (culmos) del bambú de dimensiones medianas –seccionados longitudinalmente y posteriormente reacoplados– para conformar componentes que sean de fácil implementación como estructura de apoyo para la edificación con bajareque, que como se sabe, es una de las técnicas constructivas que mejor comportamiento presentan ante fenómenos sísmicos. La técnica propuesta permite racionalizar el sistema que tradicionalmente se ha realizado de manera empírica, mediante la sistematización del control de calidad de la materia prima y la ejecución de las obras.
Intermediarios y poder de mercado en los mercados agrícolas de México: un enfoque de teoría de juegos
Authors: Chavarín Rodríguez Rubén Antonio
Published: February 2020

El objetivo del presente trabajo es modelar los efectos del poder de mercado presente en los eslabones de intermediación en los mercados agrícolas de México. Para este propósito, se elaboró un conjunto de modelos de teoría de juegos. La conclusión general del presente trabajo es que cuando un intermediario agrícola tiene poder de mercado en la fijación de su precio de venta, no sólo produce efectos en los eslabones siguientes de la cadena del producto, sino que también tiene repercusiones negativas en los productores. Este resultado se mantiene aun cuando el productor tenga poder negociador en la venta de su producto, y a pesar de que el intermediario se comporte como precio-aceptante al comprarle. Cuando además hay poder de mercado en la fijación del precio de compra, este resultado se refuerza.
El rol del capital humando en el emprendimiento regional en Ecuador: un enfoque usando métodos espaciales
Authors: Alvarado López Rafael , Jiménez Soto Cecibel , Sánchez Bustamante Belén , Ponce Ochoa Pablo
Published: February 2020

El emprendimiento es un mecanismo ampliamente utilizado para generar empleo y aumentar los niveles de producción. Sin embargo, no siempre surge de forma espontánea y más bien requiere del impulso de la política pública. En tal contexto, el objetivo de esta investigación es examinar el efecto del capital humano en la tasa de emprendimiento regional en Ecuador; utilizamos datos publicados por el Instituto Nacional de Estadísticas y Censos. Con el fin de capturar el contagio espacial que produce el nacimiento de nuevas empresas y la movilidad territorial del capital humano, estimamos un conjunto de modelos de rezago espacial (SAR), de error espacial (SEM), espacial de Durbin (SDM) y de rezago y error espacial (SARMA). Nuestros resultados destacan la importancia de la inclusión del rol del espacio en la comprensión de la interacción entre unidades territoriales y sugieren que el capital humano posee un efecto positivo en la tasa de emprendimiento regional con derrames espaciales. Los resultados son consistentes ante la inclusión de un conjunto de variables de control relacionadas con las dotaciones de las regiones. Una implicación de política pública derivada de nuestra investigación es que la planificación pública orientada a promover el nacimiento de nuevas empresas debe considerar el rol del contagio espacial del emprendimiento y la movilidad territorial del capital humano.
Efectos del comercio internacional con EE.UU. y China en el empleo manufacturero en México
Authors: Pérez Santillán Lesbia , Dussel Peters Enrique
Published: February 2020

En las últimas décadas se ha acentuado la segmentación de la producción en el mercado global. Esto ha permitido a varios países, independientemente de su nivel de desarrollo, insertarse en etapas específicas de la producción mundial, lo que a su vez ha repercutido en sus niveles y tipos de empleo. En este contexto, la economía mexicana, y en especial su sector manufacturero, se ha insertado en segmentos con un alto intercambio de exportaciones e importaciones, tanto con EE.UU., su principal socio comercial; como con China un socio que ha adquirido importancia en años recientes. Este trabajo aporta nueva información sobre los efectos que el comercio exterior manufacturero de México con EE.UU. y China tiene sobre el empleo manufacturero mexicano. Para conocer los impactos, se utiliza una variante del análisis de descomposición estructural que permitirá obtener resultados desagregados entre los factores determinantes del crecimiento del empleo, los efectos de cambios en las exportaciones y los impactos de cambios estructurales en las importaciones intermedias y finales. Las matrices insumo producto para cada país se toman de las Input-Output Tables (IOTs) publicadas por la World Input Ouput Database (WIOD) y se emplea información sobre empleo contenida en las Socio Economic Accounts (SEA) publicados también por la WIOD y desagregadas a 35 sectores.
La participación de la mujer en la economía del Estado de Yucatán
Authors: Ojeda-López Ruth Noemí , Encalada Jennifer Mul , Saavedra-García María Luisa
Published: February 2020

El presente artículo tiene como objetivo dar a conocer el papel de la mujer en la economía del estado de Yucatán. El estudio se llevó a cabo con un enfoque cuantitativo y descriptivo a partir del análisis de datos estadísticos oficiales que permitieron ofrecer un panorama de la situación laboral actual de la mujer y su participación en emprendimientos. Se utilizó como categoría de análisis el tamaño de las empresas y los sectores económicos. Con base en el análisis de los datos, se concluye que, en Yucatán, y en comparación con los hombres, existe una mayor participación de mujeres empleadas. Asimismo, éstas se encuentran laborando, principalmente, en actividades de servicios como la salud y la educación. Se destaca la labor de las mujeres como emprendedoras pues, en el estado, representan un mayor porcentaje que sus contrapartes hombres, incluso mayor que a nivel nacional.
Evaluación de los factores que influyen sobre la percepción de los empleados en cuanto a la situación de responsabilidad social de una empresa manufacturera
Authors: Sánchez-López Eduardo , González-Espinoza Mayda , Gonzalez-Larrinaga Lucio Alberto
Published: February 2020

Con el fin de definir qué factores influyen sobre la percepción de la responsabilidad social que tienen los empleados de una empresa manufacturera, se llevó a cabo una encuesta a una muestra representativa de empleados. Para ello, se utilizó un instrumento de once dimensiones formateado en una escala Likert. La información obtenida fue evaluada mediante un modelo de regresión logística binaria, en el cual la variable dependiente fue la percepción del nivel de responsabilidad social de la empresa. Las variables independientes fueron: igualdad laboral, atención a empleados con capacidades diferentes, condiciones de trabajo, derechos laborales, ambiente de trabajo, cuidado del medio ambiente, uso de agua, ética, respeto a propiedad intelectual, aplicación de leyes y reglamentos, así como el sexo del entrevistado. La estimación del modelo resultó en que solo las variables: ambiente de trabajo, uso de agua y cumplimiento de leyes y reglamentos resultaron significativas (p<.05); todas ellas presentaron un OR superior a 1.5. La significancia de tan solo tres variables indica la necesidad de que la empresa mejore su situación de responsabilidad social.
Empresa familiar y la teoría de sistemas luhmanniana
Authors: Vera-Muñoz Gerardo , Martínez-Méndez Rafaela , Vera-Muñoz María Antonieta
Published: February 2020

El objetivo es analizar algunos aspectos de la problemática de la empresa familiar tomando como referencia la teoría de sistemas de Niklas Luhmann. La investigación es eminentemente teórica. Para llevarla a cabo, se revisaron fuentes secundarias como, artículos y libros sobre la empresa familiar y la teoría de sistemas luhmanniana. Posteriormente, apoyados en los fundamentos de esta teoría, se proponen una serie de hipótesis de trabajo que coadyuven a tener un conocimiento más puntual sobre la problemática de la empresa familiar. Partiendo de la idea que una organización es un sistema social que se constituye a través de la comunicación de decisiones, se propone que la problemática de la empresa familiar esencialmente tiene sus orígenes en la confrontación cotidiana de códigos de comunicación radicalmente opuestos. Asimismo, se presume que estas unidades empresariales debido a su limitada complejidad: escases de recursos y capacidades; enfrentan graves problemas para adaptarse a su entorno. O debido a sus propias determinaciones y operaciones internas, no tienen ningún interés en perpetuar tal adaptación.
The p53 Slavic Gene Mutation Nijmegen Breakage Syndrome
Authors: Saptarshi Pal  , Elena Ponomarenko
Published: February 2020

Nijmegen breakage syndrome is a rare autosomal congenital disorder. It originates from mutations in the NBS1 gene located in band 8q21, which encodes for the DNA double strand repair protein Nibrin. Immunodeficiency with increased susceptibility to infection. It is a condition characterized by short stature, an unusually small head size (microcephaly), distinctive facial features, recurrent respiratory tract infections, an increased risk of cancer, intellectual disability, and other health problems. People with this condition typically grow slowly during infancy and early childhood. After this period of slow growth, affected individuals grow at a normal rate but remain shorter than their peers. Microcephaly is apparent from birth in the majority of affected individuals. The head does not grow at the same rate as the rest of the body, so it appears that the head is getting smaller as the body grows (progressive microcephaly).Individuals with Nijmegen breakage syndrome have distinctive facial features that include a sloping forehead, a prominent nose, large ears, a small jaw, and outside corners of the eyes that point upward (up slanting palpebral fissures). These facial features typically become apparent by age 3.

Keywords: Nijmegen breakage syndrome; Chromosomal instability; Immunodeficiency; Microcephaly
Membership of Czech municipalities to rural and urban areas: a fuzzy-based approach
Authors: Pászto Vít , Burian Jaroslav , Marek Lukáš , Voženílek Vít , Tuček Pavel
Published: February 2020

Due to the ongoing changes in settlement, it is becoming increasingly difficult to properly define rural and urban areas in Czechia. This delimitation problem has been intensively studied in Europe, including Czechia, for decades, but only the “crisp” rules have been set for this purpose. This is no longer sufficient because of substantial population movements. Our research focused on applying the fuzzy set theory to the delimitation of rural and urban areas and on a subsequent visualization and statistical comparison. This paper focuses on an introduction of such approaches and aims to present the chances of using geocomputational methods in geographical research. The main result is a new methodology that applies the principles of fuzzy approach (fuzzy sets and numbers operations, fuzzy regulation) on socio-economic data to show the transitional character of municipalities. Two ways of fuzzy approach, the easy-to-obtain Łukasiewicz T-norm and the more complex fuzzy regulation, are used in order to demonstrate its advantage over the Boolean logic procedure in the delimitation of rural and urban areas.
NON-LINEAR AND LAGGING CONVERGENCE EFFECTS OF THE EU’S REGIONAL SUPPORT AT NUTS 3 LEVEL
Authors: BUTKUS Mindaugas , CIBULSKIENĖ Diana , MAČIULYTĖ-ŠNIUKIENĖ Alma , MATUZEVIČIUTĖ Kristina
Published: February 2020

Reduction of the territorial disparities in terms of their development level is the main aim of the European Union’s (EU’s) regional support. Most of the previous studies investigate the linear relationship between support and growth at countries’ or NUTS1/2 disaggregation level, omitting the question on what is the impact of this support on regional convergence among NUTS3 regions and on whether non-linear effects occur. To fill this gap, we modified the difference-in-differences estimator to test empirically the non-linear convergence effects of the EU’s regional support at NUTS 3 level over the 2000-2006 programming period, taking into account the possible lagging effect. The results revealed that the impact of regional support on convergence is positive with the diminishing marginal effect as the intensity of payments is increasing. Moreover, we find evidence that the return is higher for the post-intervention compared with the intervention period, i.e. the convergence outcomes of the EU’s support occur in the long-run.
Analisis Kandungan Gizi Beras dari Beberapa Galur Padi Transgenik Pac Nagdong/Ir36
Authors: Fitriyah Dina , Ubaidillah Mohammad , Oktaviani Fariza
Published: February 2020

Rice that is generally consumed by Indonesian people is that does not have important nutrient such as β-carotene. Therefore, the way to supply β-carotene requirement in staple foods can be done through β-carotene biofortification by genetic engineering of the rice plant. PAC Nagdong/ IR36 is transgenic Golden Rice which can produce β-carotene. The research aimed to determine some nutritional content of PAC Nagdong/ IR36 rice lines that include carbohydrate, amylose, amylopectin, protein, lipid, and β-carotene content. Amylose was measured using the iodine colorimetric method, whereas the contents of amylopectin and carbohydrates were measured using the by difference method. Protein was measured using the Bradford method, lipid was measured using Proctor and Bowen method, while β-carotene content was measured using the colorimetric method. PAC Nagdong/ IR36 rice lines had carbohydrate content between 85,06-90,16%, amylose 12,94%- 20,81%, amylopectin 69,35- 76,17%, protein 7,76-8,52 µg/µl, lipid 0,65-0,90%, and β-carotene 231,61-920,52 µg/g. Carbohydrate, protein, and β-carotene in PAC Nagdong/ IR36 were higher than TN1 rice variety (control). This indicated that PAC Nagdong/ IR36 provided better nutrition. Amylose content of Nagdong/ IR36 PAC rice was low, which donated its potential to produce fluffier rice whereas high β-carotene content could be used as a source of β-carotene that is useful in overcoming vitamin A deficiency and beneficial for health including in preventing degenerative diseases.
Gambaran Motorik Anak Yang Menggunakan Alat Permainan Edukatif Di TK DCC 2019
Authors: Zamzami Mohamad Rheza Firmansyah , Ladyani Mustofa Festy , Supriyati
Published: February 2020

Child development‘s delay in Indonesia based on the Indonesia Ministry of  Health was 16% of a total toddler in Indonesia. The various factors affecting the child’s development, such as the stimulation of the educative game instrument (EGI). Increase of the use of EGI in other countries proportional to the child’s development aspect but not in Indonesia. To know the overview of the motor development level of preschool-aged children towards the educative game instrument at Dian Cipta Cendekia (DCC) Global School Kindergarten 2019. A descriptive quantitative study by using an observational approach was performed. The data were collected using a review of the school report, the use of the EGI, and the ability to follow the commands based on Denver II categories.  This research was done during November 2019. There were six samples from class b taken using a total sampling method. 1 of  6 children failed by following 1 of 12 activities based on Denver II. One of them couldn’t use the climbing frames properly, and based on the school report, 1 of  6 children stated as not developing yet by knowing the traffic sign. The level of using EGI proportional to the child’s development aspect. The frequency distribution of the use of EGI shown 91,7% good. An overview of motor development level based on school report shown 54,2% normal development and 100% normal by Denver II.
Chinese-as-a-Foreign-Language Learners’ Use of Self-Regulated Learning in Flipped/Blended Learning Environments – A Descriptive Study
Authors: Zhang Shenglan
Published: February 2020

Self-regulated learning (SRL) is especially important in blended/flipped learning environments. This study explored and described the use of SRL in a specific language learning context. It investigated what problems Chinese-as-a-foreign-language learners (CFL) had with their Chinese language learning, whether and how they solved the problems, what SRL strategies they adopted, and what support they needed to gain the maximum benefits from the blended/flipped learning environment. Nineteen CFL learners who were in their second semester studying Chinese in a blended/flipped environment participated in the descriptive study. Self-reported data were collected using WeChat in an individualized exchange format, which was designed to help with data richness, completeness, and accuracy. The results show that students had different problems in learning, and they would benefit if they had the opportunity to learn and incorporate SRL strategies. The areas in which they needed the most help were knowing how to set a goal, how to create a plan to achieve the goal, and how to use different strategies to manage their learning and manage their time. Implications for teaching are also discussed in this study.
Betulinic Acid Enhances the Sensitivity of Multiple Myeloma Cells to Bortezomib by the Inactivation of the AKT/mTOR Pathway
Authors: Dan Yu , Sheng Wan , Lili Hu
Published: February 2020

This study aimed to investigate the mechanism of betulinic acid on multiple myeloma cell resistance to bortezomib. To this end, the bortezomib-resistant RPMI-8226-R cells were generated by prolonged treatment of RPMI-8226 cells with increasing concentrations of bortezomib. Based on the measurements of cell viability and colony number, RPMI-8226-R cells exhibited enhanced resistance to bortezomib than RPMI-8226 cells. Treatment with betulinic acid resulted in increased sensitivity of RPMI-8226-R to bortezomib. When RPMI-8226-R cells were co-treated with bortezomib and betulinic acid, there was an increase in apoptosis rate, cleaved caspase-3, cleaved caspase-9 expression and the decrease in p-AKT/AKT and p-mTOR/mTOR levels. These results suggest that betulinic acid enhances the sensitivity of RPMI-8226-R cells to bortezomib by inhibiting the activation of the AKT/mTOR pathway in bortezomib-resistant multiple myeloma cells.
Point to Point: Responses to “Reconsidering the Effectiveness and Suitability of PPP and TBLT in the Japanese Classroom”
Authors: Sybing Roehl , Urick Steven , Sato Rintaro
Published: February 2020

Point to Point

A Response to Criticism of TBLT in Japan’s Language Classrooms — Roehl Sybing
On Methodology in Japanese Secondary English Classrooms — Steven T. Urick
The Author Responds: A Reply to Responses to “Reconsidering the Effectiveness and Suitability of PPP and TBLT in the Japanese Classroom” — Rintaro Sato (佐藤臨太郎)
Formation of nanoripples on ZnO flat substrates and nanorods by gas cluster ion bombardment
Authors: Zeng Xiaomei , Pelenovich Vasiliy , Xing Bin , Rakhimov Rakhim , Zuo Wenbin , Tolstogouzov Alexander , Liu Chuansheng , Fu Dejun , Xiao Xiangheng
Published: February 2020

In the present study Ar+ cluster ions accelerated by voltages in the range of 5–10 kV are used to irradiate single crystal ZnO substrates and nanorods to fabricate self-assembled surface nanoripple arrays. The ripple formation is observed when the incidence angle of the cluster beam is in the range of 30–70°. The influence of incidence angle, accelerating voltage, and fluence on the ripple formation is studied. Wavelength and height of the nanoripples increase with increasing accelerating voltage and fluence for both targets. The nanoripples formed on the flat substrates remind of aeolian sand ripples. The ripples formed at high ion fluences on the nanorod facets resemble well-ordered parallel steps or ribs. The more ordered ripple formation on nanorods can be associated with the confinement of the nanorod facets in comparison with the quasi-infinite surface of the flat substrates.
Analisis Besaran Dividen Terhadap Besaran Laba Perusahaan
Authors: Hakim Lukmanul , Ariffin Muhammad
Published: February 2020

Dividend amount is distribution of profit yielded by a company to the shareholders. The amount of dividend influences the amount of profit at the company.The objective of this research is to find out the amount of dividend distributed, how much profit is generated, and the influence of dividend and profit amount. The indicators are the dividend amount utilizes dividend in equity change statement and dividend per share (DPS), and the profit amount makes use of net profit in profit and loss statement and net profit margin (NPM). The data used are two companies running on the same consumers during six years – 2005 up to and including 2010.The method used is ratio dividend, to find out how much the dividend distributed and the profit ratio are, to know how much the profit earned by the company will be, and to detect the correlation between the two variables above. They have been processed utilizing SPSS 17.0.

Based on the research yield, it can be concluded that the two companies have different correlation fact. There is positive correlation between dividend amount and profit amount at PT Mayora Indah Tbk., the dividend increase is followed by the profit increase due to the external factor, that is the debt has been empowered efficiently. The other way, there is negative correlation between dividend amount and profit amount at PT Delta Djakarta, that is the dividend increase does not followed by the profit increase due to the debt has not been empowered efficiently.

 

Keywords:dividend amount; profit amount
Membangun Brand Image Mahasiswa Atas Produk Shampo Pantene Melalui Pemilihan Selebrity Endorser Studi Kasus Anggun C Sasmi Sebagai Selebrity Endorser
Authors: Juliap B. Rika , Zuhdi Saefudin , Supariyani Emmy
Published: February 2020

Celebrity endorser is one of marketing communication. The use of endorser is to lift more famous product’s brand. Generally use an endorser as a celebrity is to invite people to always remember the brand on their mind. So is needed a appropriate selection of celebrity endorser with the product to be brought. It is expected to affect the brand image of a product. The purpose of this study was to determine the effect of celebrity endorser selection of brand image. To find out is to find out how a good selection of celebrity endorser and appropriate so as to produce a positive brand image of a product. Research on the author is in STIE Kesatuan Bogor. By using quantitative descriptive method and causality.

The result and discussion showed that Pantene celebrity endorser selectively chose the sight of the commitment of their endorser, her profession is evident in each of their carrier success. The selection process of Anggun C. Sasmi to endorse Pantene is need a quite long. This affects the Pantene’s brand image as a market leader in the position of hair science which gained several awards. Celebrity endorser selection of indicators source credibility, source attractiveness, meaning transfer, and celebrity product congruence. Source credibility of Anggun C. Sasmi was not much influence on brand image of Pantene shampoo. While a celebrity product congruence has a positive influence, dominant, significant. Value of r or the correlation coefficient between the celebrity endorser’s selection of celebrity endorsers (X) with the brand image (Y) of 0,663 means that the relation between these variables is strong. It means that if X then Y up one unit will respond by 66,3%. So, the celebrity endorser’s selection which have a right process will affect the brand image of Pantene shampoo products.

Keywords: celebrity endorser, brand image, Shampoo
Pengaruh Pelayanan Terhadap Kepuasan Pelanggan dan Implikasinya Terhadap Citra Perusahaan Studi Kasus Pada Hotel Mirah Bogor
Authors: Maulana Miki , Mulyana Mumuh
Published: February 2020

Service is a kind of direct and indirect communication from the producen to the costumer to measure how for the customer to buy and consume, if they can have satisfaction to the product that they will trust and keep using our product.

The main target of this research is the identification how good is the service that give by MIRAH HOTEL Bogor, how big is the customer satisfaction MIRAH HOTEL Bogor.The method of analysis is quantitative method with regretion and correlation formula, to answer of question, when questioner used and draft to respondent. The Implication to image of the company a djuge from how the service and facilities inside MIRAH HOTEL bogor,  customer satisfaction and its implications for corporate image in question. services have a significant effect on perceived ease of customer satisfaction with a coefficient of 0,46. It can be proved by looking at the value of t statistics of 6,26 greater than 1,96. PLS results indicate that the construct of service quality has a positive effect on customer satisfaction This means that the first hypothesis is accepted, the proven quality of service  effect customer satisfaction. Quality of service that increases customer satisfaction  causes more significant effect on perceived ease of customer satisfaction with the coefficient of 0,46. It can be proved by looking at the value of t statistics for 11,90 of greater than 1,96. While the second hypothesis customer satisfaction has a positive effect on corporate image study was to prove the second hypothesis is accepted, customer satisfaction is proven to effect the company's image.

 

Keywords :  Service, Customer Satisfaction, Brand Image
Analisis Fundamental Saham Terhadap Pertumbuhan Perusahaan STUDI KASUS PADA PT. HOLCIM INDONESIA, TBK.
Authors: Marpaung Annaria Magdalena
Published: February 2020

Fundamental analysis is a method of analysis using the fundamental strength of a country. In general, the fundamental strength of a country is shown by the country’s economic data. Fundamental analysis states that every stock has an intrinsic value. This analysis attempts to calculate the intrinsic value of a stock by using the fundamental data of the “ Company’s Financial Statements “, such as earning devidends, sales, capital structure, risk etc. This analysis will compare the intrinsic value with the market value to determine whether the market price of shares has reflected its intrinsic value or has not. The purpose of this study is to find out the company’s fundamental analysis with the liquidity ratio, the company’s growth, and the impact of the analysis on the company’s growth. The result of the research indicates that the two public companies analyzed for six years in terms of cash and cash equivalents, inventories, current assets and current liabilities is that PT. Holcim Indonesia, Tbk was stable. Concerning profit growth, PT. Holcim Indonesia, Tbk yielded profit. The analysis of those factors shows that it has positive effect for PT. Holcim Indonesia, Tbk which causes many investors will invest their funds.

Keywords : Fundamental analysis; liquidity ratio; company’s growth
Pengaruh Laba Terhadap Likuiditas Perusahaan
Authors: Supriadi Yoyon , Gendalasari Gen Gen
Published: February 2020

Each company established course aims to derive a profit or benefit that can be used for the welfare of the company owners or shareholders. In every company liquidity is an important part of measuring the extent to which companies are able to pay maturing obligations to its creditors. Liquidity is a measure of investor decision-making, in which investors learn the level of liquidity and profitability in order to take the right decision for the future. Through this research are expected to know how the liquidity of the company if it is in accordance with the standard value of liquidity compared with the same company with a view of the profit, if not then impact whether and how the best solution which can be given to the company. Regression coefficient PT. Medco Energi International Tbk shows that Return On Assets (ROA) has a positive effect on the current ratio. The result of F test for the company showed no significant effect between Return On Assets (ROA) of the current ratio, this is because there are other factors that affect the current ratio. PT. Medco Energi International has a significant effect between Return On Assets (ROA) on the current ratio.

 

Keywords : Return, Liquidity, Profit.
Pengaruh Atribut Produk Herbal Terhadap Kepuasan Pelanggan
Authors: Sad Raden Irwan , Sukartaatmadja Iswandi
Published: February 2020

Given the company's product attributes can know how much the level of customer satisfaction the company's products. To that end, the company has its own unique way and in a typical product attributes that customers will feel satisfied when buying products. Marketing activities can be done by improving and providing innovation to the product will be in production. Where products are manufactured must have a good product attributes in accordance with customer expectations, and creating customer satisfaction. This study aims to know the attributes of Herbal Products manufactured by Raudhoh. To find out the customer satisfaction in taking Herbal Products from Raudhoh. To determine the effect of product attributes on customer satisfaction Herbal Products Brand Raudhoh Raudhoh on international companies. The results showed the customer satisfaction of international raudhoh herbal products is 9.781. The calculated value of the correlation coefficient of 0.676 is obtained which means that there is a significant relationship with the closeness of the relationship strong and positive relationship between product attributes to customer satisfaction. the results obtained from the coefficient of determination 0.457, which means that the community has a contribution of 45.7% in creating customer satisfaction, and the rest is influenced by other factors

 

Keywords: product attributes, customer satisfaction
The Nature of the Double Nuclei in the Barred S0 Galaxy IC 676
Authors: Zhou Zhimin , Ma Jun , Zhou Xu , Wu Hong
Published: February 2020

The lenticular galaxy IC 676 is a barred galaxy with double nuclei and active star formation in the central region. In this work we present the long-slit spectroscopy and archival multiwavelength images to investigate the nature and origin of the double nuclei in IC 676. Through photometric 1D brightness profiles and 2D image decomposition, we show that this galaxy consists of a stellar bar with the length of ∼2.5 kpc and two Sérsic disks both of which with Sérsic index n ∼ 1.3. There is probably little or no bulge component assembled in IC 676. The luminosities of the double nuclei are primarily dominated by young stellar populations within the ages of 1–10 Myr. The northern nucleus has stronger star formation activity than the southern one. The surface densities of the star formation rate in the double nuclei are similar to those in starburst galaxies or the circumnuclear star-forming regions in spiral galaxies. Each of the double nuclei in IC 676 likely consists of young massive star clusters, which can be resolved as bright knots in the Hubble Space Telescope high-resolution image. Our results suggest that IC 676 likely has a complex formation and evolutionary history. The secular processes driven by the stellar bar and external accretion may dominate the formation and evolution of its double nuclei. This indicates that the secular evolution involving the internal and external drivers may have an important contribution for the evolution of lenticular galaxies.
The Carnegie-Irvine Galaxy Survey. IX. Classification of Bulge Types and Statistical Properties of Pseudo Bulges
Authors: Gao 高 Hua 桦 , Ho Luis C. , Barth Aaron J. , Li Zhao-Yu
Published: February 2020

We study the statistical properties of 320 bulges of disk galaxies in the Carnegie-Irvine Galaxy Survey, using robust structural parameters of galaxies derived from image fitting. We apply the Kormendy relation to classify classical and pseudo bulges and characterize the bulge dichotomy with respect to the structural properties of the bulges and the physical properties of the host galaxies. We confirm previous findings that pseudo bulges on average have smaller Sérsic indices, lower bulge-to-total ratios, and fainter surface brightnesses than classical bulges. Our sizable sample statistically shows that pseudo bulges are more intrinsically flattened than classical bulges. Pseudo bulges are most frequent (incidence ≳80%) in late-type spirals (later than Sc). Our measurements support the picture in which pseudo bulges arose from star formation induced by inflowing gas, while classical bulges were born out of violent processes such as mergers and coalescence of clumps. We reveal differences with the literature that warrant attention: (1) the bimodal distribution of Sérsic indices presented by previous studies is not reproduced in our study; (2) classical and pseudo bulges have similar relative bulge sizes; and (3) the pseudo bulge fraction is considerably smaller in early-type disks than reported in previous studies based on one-dimensional surface brightness profile fitting. We attribute these differences to our improved image quality, more robust bulge-to-disk decomposition technique, and to the different classification criteria that we applied. Moreover, we find that barred galaxies do not host more pseudo bulges or more prominent pseudo bulges than unbarred galaxies. Various implications of these findings are discussed.
Oenopia shirkuhensis sp. nov. (Coleoptera, Coccinellidae) from Iran mimicking Adalia bipunctata
Authors: Zare Khormizi Mehdi , Nedvěd Oldřich
Published: February 2020

Oenopia shirkuhensissp. nov. (Coleoptera, Coccinellidae) is described and illustrated. It was found in the mountains around Shirkooh mountain, Yazd province, and in the Kukhbenan Mountains, Kerman province, Iran. It is similar to a common ladybird Adalia bipunctata by the colour pattern on elytra. Congeneric species occurring in Iran, O. conglobata and partly O. oncina are illustrated for comparison, and an identification key is provided.
Leukocyte count: A reliable marker for the severity of organophosphate intoxication?
Authors: Kumar Sunil , Agrawal Sachin , Raisinghani Nitin , Khan Shameem
Published: February 2020

INTRODUCTION: Organophosphorus poisoning (OPP) is a major public health problem in developing countries like India. Leukocyte count is a simple and inexpensive test, and elevated count is associated with acute inflammation and increased oxidative stress-like OPP. This study was done to correlate the severity of acute OPP with leukocyte count and also to assess the prognosis.

MATERIALS AND METHODS: A prospective, observational clinical study was done on 80 patients suspected of OPP of age >15 years admitted to emergency unit at a tertiary rural teaching health-care center of Central India. Serum cholinesterase level and leukocyte count were estimated at the time of admission in all patients and severity of OPP was assessed according to Peradeniya organophosphorus poisoning (POP) scale.

RESULTS: The mean age of the patients was 33.52 years (standard deviation [SD] 11.62) in males and 27.30 years (SD 7.33) in females. Among them, 57 (71.25%) were males and 23 (28.75%) were females. The severity of poisoning was directly correlated with serum cholinesterase level (P = 0.0001). Leukocyte count had a sensitivity of 60%, specificity of 76%, and negative predictive value of 85% if counts were more than 12,000 and 30% sensitivity, 95% specificity, and 80% negative predictive value if counts were more than 15,000 in predicting mortality in patients with OPP.

CONCLUSION: Leukocyte count levels on admission can be used a prognostic marker in patients with OP poisoning.
Sigma metrics as a tool for evaluating the performance of internal quality control in a clinical chemistry laboratory
Authors: Kumar B. Vinodh , Mohan Thuthi
Published: February 2020

OBJECTIVE: Six Sigma is one of the most popular quality management system tools employed for process improvement. The Six Sigma methods are usually applied when the outcome of the process can be measured. This study was done to assess the performance of individual biochemical parameters on a Sigma Scale by calculating the sigma metrics for individual parameters and to follow the Westgard guidelines for appropriate Westgard rules and levels of internal quality control (IQC) that needs to be processed to improve target analyte performance based on the sigma metrics.

MATERIALS AND METHODS: This is a retrospective study, and data required for the study were extracted between July 2015 and June 2016 from a Secondary Care Government Hospital, Chennai. The data obtained for the study are IQC - coefficient of variation percentage and External Quality Assurance Scheme (EQAS) - Bias% for 16 biochemical parameters.

RESULTS: For the level 1 IQC, four analytes (alkaline phosphatase, magnesium, triglyceride, and high-density lipoprotein-cholesterol) showed an ideal performance of ≥6 sigma level, five analytes (urea, total bilirubin, albumin, cholesterol, and potassium) showed an average performance of <3 sigma level and for level 2 IQCs, same four analytes of level 1 showed a performance of ≥6 sigma level, and four analytes (urea, albumin, cholesterol, and potassium) showed an average performance of <3 sigma level. For all analytes <6 sigma level, the quality goal index (QGI) was <0.8 indicating the area requiring improvement to be imprecision except cholesterol whose QGI >1.2 indicated inaccuracy.

CONCLUSION: This study shows that sigma metrics is a good quality tool to assess the analytical performance of a clinical chemistry laboratory. Thus, sigma metric analysis provides a benchmark for the laboratory to design a protocol for IQC, address poor assay performance, and assess the efficiency of existing laboratory processes.
Value of cytokeratin-19, Hector Battifora mesothelial-1 and galectin-3 immunostaining in the diagnosis of thyroid neoplasms
Authors: Sanuvada Rajasekhar , Nandyala Rukmangadha , Chowhan Amit Kumar , Bobbidi Phaneendra , Yootla Mutheeswariah , Hulikal Narendra , Sachan Alok
Published: February 2020

BACKGROUND: Diagnosis of types and aggressiveness of thyroid cancers is difficult. The "gold standard" in diagnosis is using routine hematoxylin and eosin staining. Several markers have been investigated for differentiating them among which cytokeratin-19 (CK-19), Hector Battifora mesothelial cell (HBME-1), and galectin-3 are found to be most commonly used. Most studies have evaluated the single expression of markers in various thyroid lesions.

AIMS AND OBJECTIVES: To know the value of immunohistochemical expression of CK-19, HBME-1, and galectin-3 in diagnosing thyroid neoplasms. To study the expression and compare the results of HBME-1, CK-19, and galectin-3 immunohistochemical markers in histopathologically diagnosed malignant lesions and nonmalignant lesions and demonstrate their usefulness in differentiating them.

MATERIALS AND METHODS: A prospective study was carried out on thyroidectomy specimens sent in 10% buffered formalin to Department of Pathology, SVIMS, Tirupati, from May 2013 to August 2014. Sensitivity and specificity for each marker and their combination in diagnosis were calculated.

RESULTS: Among 120 cases, nonmalignant lesions were 70 (58.33%) and malignant lesions 50 (41.67%). Among nonmalignant lesions, 65 (93%) were adenomatous goiter and 5 (7%) were follicular adenomas. In malignant lesions, 48 (96%) were papillary carcinoma and 1 (2%) each of follicular carcinoma and anaplastic carcinoma. Among papillary carcinomas, classical were 26 (54.16%) followed by 17 follicular variant (35.41%). Galectin-3 had highest sensitivity of 90% and HBME-1 had highest specificity of 97.14%.

CONCLUSIONS: Panel of HBME-1+ galectin-3 or CK-19, HBME-1, and galectin-3 increase the accuracy of diagnosis in histopathologically difficult cases.
Occurrence of bla genes encoding carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii from Intensive Care Unit in a tertiary care hospital
Authors: Subramaniyan Jayanthi Siva , Sundaram Jeya Meenakshi
Published: February 2020

CONTEXT: ICU shows increasing incidence of infection associated with the use of invasive procedures for the diagnostic purpose as well as the indiscriminate use of antibiotics. Pseudomonas aeruginosa and Acinetobacter species are "very successful" pathogen and the emergence of the Metallo-β-Lactamases (MBL) is becoming a therapeutic challenge.

AIMS: To isolate the Nonfermenting Gram negative bacilli from the ICU samples. To identify the metallo betalactamase producers and to detect the bla gene presence among the Pseudomonas aeruginosa and Acinetobacter baumannii.

SETTINGS AND DESIGN: The Nonfermenting Gram negative bacilli isolates from the ICU samples were taken over for 5 years (2009-2014) in a tertiary care hospital.

METHODS AND MATERIALS: The isolates of Pseudomonas species and Acinetobacter species were confirmed by API analyser and processed according to standard procedures. Detection of the MBL producers were done by E strip method and subjected for bla gene detection by PCR method.

RESULTS: In our study a total of 195 isolates of NFGNB were obtained from various ICU. Of these MBL producers, 26 % were Pseudomonas aeruginosa and 25 % were Acinetobacter baumannii. The subtypes of bla
VIMMBL producing P.aeruginosa were 26%.The predominant gene coding for MBL activity in A.baumannii were found to be bla
OXA gene 11.9%. The gene accession numbers were KF975367, KF975372.

CONCLUSIONS: We have to control the development and dissemination of these superbugs among the ICU's.
HBG2 -158 (C>T) polymorphism and its contribution to fetal hemoglobin variability in Iraqi Kurds with beta-thalassemia minor
Authors: Albarawi Dilan J. , Balatay Amer A. , Al-Allawi Nasir
Published: February 2020

PURPOSE: Hemoglobin (Hb) F% is increased in up to half of beta-thalassemia (β-thal) carriers. Several polymorphisms have been linked to such variability in different populations, including HBG2 - 158(C>T) (Xmn I polymorphism) on chromosome 11. To determine the role of this polymorphism in such variability among Iraqi Kurds, the current study was initiated.

MATERIALS AND METHODS: A total of 102 consecutive patients diagnosed as β-thal minor were enrolled. The enrollees had their diagnosis based on peripheral blood counts and high-performance liquid chromatography to determine HbA2 and HbF. All enrollees had their DNA extracted by phenol-chloroform method and Xmn I polymorphism detected by restriction fragment length polymorphism-polymerase chain reaction.

RESULTS: The mean age (standard deviation [SD]) of the 102 enrollees was 25.4 (14.0) years, and the enrollees included 48 males and 54 females. Xmn I polymorphism was identified in heterozygous state in 46 (45.1%) patients and in homozygous state in one patient (0.98%). Thus, the minor allele frequency of this polymorphism was 0.235 in the studied group. There were no significant differences in red cell indices and HbA2% in carriers of the minor allele compared to noncarriers, while HbF% and absolute HbF concentrations were significantly higher in the former subgroup (P = 0.032 and 0.014, respectively). This polymorphism's contribution to HbF variability was found to be 5.8% in the studied sample. Furthermore, those with HbF ≥2% were 3.2 folds more likely to carry the minor allele.

CONCLUSIONS: Xmn I polymorphism is frequently encountered in Iraqi Kurds with β-thal minor, and it is significantly associated with higher fetal hemoglobin in these patients.
Diagnostic challenges of tubercular lesions of breast
Authors: Jairajpuri Zeeba Shamim , Jetley Sujata , Rana Safia , Khetrapal Shaan , Khan Sabina , Hassan Mohammad Jaseem
Published: February 2020

INTRODUCTION: Tuberculosis (TB) in the developing countries presents with both pulmonary and extrapulmonary manifestations. Breast TB, however, remains a rare presentation. Its importance lies in the fact that it may mimic malignancy or present as inflammatory lump/abscess.

AIMS AND OBJECTIVE: The aim of the present study is to highlight the importance of breast TB and its diagnostic challenges.

MATERIALS AND METHODS: It was a retrospective study conducted at a tertiary care hospital, over 2 years between 2013 and 2015 during which eight cases of breast lesions were diagnosed as of tubercular origin.

RESULTS: Granulomas were seen in five cases while three cases revealed only few epithelioid cells, and necrosis was seen in all cases on fine-needle aspiration cytology. Histopathological evaluation was available in six out of the eight cases, while acid–fast bacilli were positive in three cases, the characteristic granulomas were seen in all the six cases evaluated.

CONCLUSION: Significance of TB breast lies in the fact that it may masquerade as breast malignancy or pyogenic abscess. India is a developing country where TB is endemic, a high index of suspicion should be expressed in evaluating breast masses, and TB should be considered in the differential diagnosis.
Prevalence of blaKPC and its occurrence with other beta-lactamases in Klebsiella pneumoniae
Authors: Remya Poothakuzhiyil , Shanthi Mariappan , Sekar Uma
Published: February 2020

BACKGROUND: Klebsiella pneumoniae (K. pneumoniae) is an important nosocomial pathogen, and the emergence of multidrug resistance in these organisms limits the treatment options for serious infections caused by them. K. pneumoniae carbapenemase (KPC) is one of the clinically significant Class A beta-lactamases.

AIM AND OBJECTIVE: This study was aimed to detect the KPC and its coexistence with other beta-lactamases in K. pneumoniae.

MATERIALS AND METHODS: A total of 370 isolates, collected over a period of 1 year, were included in this study. The source of these isolates were urine (n = 170), exudative specimens (n = 132), respiratory secretions such as bronchial wash, endotracheal aspirate, and pleural fluid (n = 38), and blood (n = 30). For all the isolates, antibiotic susceptibility tests by disc diffusion, modified Hodge test, and KPC screening test were done. Polymerase chain reaction (PCR) was performed for the detection of KPC and the copresence of other beta-lactamases genes.

RESULTS: Among the 370 isolates, 41 were resistant to the carbapenem by disc diffusion and minimum inhibitory concentration tests. Screen test using ertapenem and the boronic acid disk was positive in 14 isolates. Only one isolate harbored KPC gene by PCR, and it was co-produced with SHV-12 and CTX-M-15.

CONCLUSION: PCR remains the gold standard for detection of KPC compared with any other phenotypic methods. Early detection of these genes helps in initiating proper antibiotic treatment.