bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospects of bioinformatics approach for exploring and mapping potential bioactive peptide of Rusip (The traditional Indonesian fermented anchovy): A Review
Authors: Alfid Kurnianto Muhammad , Syahbanu Fathma , Hamidatun Hamidatun , Defri Ifwarisan , Aristya Sanjaya Yushinta
Published: July 2023

Rusip is a traditional Indonesian side-dishes food that is a fermented anchovy product originating from Bangka Belitung. During the fermentation, various lactic acid bacteria grew in rusip and produced bioactive peptides because of proteolytic enzyme action. Several treatments to obtain bioactive peptides can be conducted (fermentation, in vivo digestion, and in vitro hydrolysis using enzymes). The in vivo and in vitro methods are a widely used approach, but these methods are costly and time-consuming. These limitations could be solved by the bioinformatics approach. This method manages and interprets information about biological systems that employ computational methods. This study aimed to review recent studies on rusip and similar fermented fish and peptide bioactive with their bioactivity), steps, advantages, and limitations of bioactive peptide studies using the bioinformatics approach. The review article was written using narrative literature review method, which based on in-depth investigation from scientific literatures by identifing keywords, reviewing the content of articles, and synthesizing the findings. The results showed that using bioinformatics has provided opportunities for the development of bioactive peptides. Through this method, bioactive peptide identification begins with determining the main sample protein and the enzymes in protein hydrolysis. The further steps are protein hydrolysis simulation, determining the potential for bioactivity, and molecular docking. The bioinformatics analyses were performed synergistically to predict the protein or peptide characteristics from the sample and its bioactivity and determine its interaction with their receptor. However, despite the advantages, the bioinformatics approach also has several limitations, such as the lack of certain types of proteins or peptides in the database and hydrolysis simulation tool. Combining conventional and in silico methods (hybrid method) is potential to obtain the new and promising bioactive peptides from rusip and other fermented fish (i.e., budu, bekasam, and pla duk ra) and meat products for development product, both functional food and supplements.
Identification of Fusarium oxysporum f.sp cepae race 4 isolated from shallots in East Java Indonesia
Authors: Nur Yudha Moch , Wiyatiningsih Sri , Mujoko Tri
Published: July 2023

Fusarium oxysporum f.sp cepae (Foce) which causes moler disease, has been mutated into four races. The fourth race is the riskiest due to its vulnerability to being attacked by various cultivars. This research aims to identify the existence of Foce Race 4 in the shallot production center districts. The plant samples attacked by moler disease were taken in three districts (i.e., Magetan, Nganjuk, and Probolinggo) by Purposive Random Sampling method with 5% samples, obtaining 9 Foce isolates. The results were then identified using Volatile Odor Test (VOT), Biochemistry, and Vegetative Compatibility Group (VCG); four were identified as Race 4. Those four isolates were then examined for their virulences towards three cultivars, particularly Bauji, Tajuk, and Biru Lancor. The findings show that all four isolates were noxious and able to plague all the varieties.
Exploring Nursing Research Culture in Clinical Practice: Qualitative Ethnographic Study (Preprint)
Authors: Hwang Hyeyoung , De Gagne Jennie C , Yoo Leeho , Lee Miji , Jo Hye Kyung , Kim Ju-eun
Published: July 2023

BACKGROUND

Cultivating a positive research culture is considered the key to facilitating the utilization of research findings. In the realm of clinical nursing research, nurses conducting research may find the utilization of findings challenging due to the lack of a positive research culture.

OBJECTIVE

This study aims to identify and describe the sociocultural context of nursing research in a clinical setting at a Korean tertiary hospital.

METHODS

We included participant observation and ethnographic interviews with 6 registered nurses working in a medical-surgical unit in a Korean tertiary hospital who had experience conducting nursing research in clinical settings in this qualitative ethnographic study. The study was conducted from April 2022 to May 2022. Data analysis was conducted using Spradley’s ethnographic approach, which includes domain analysis, taxonomic analysis, componential analysis, and theme analysis, and occurred concurrently with data collection.

RESULTS

The overarching theme identified for nursing research culture in clinical practice was the development of a driving force for growth within the clinical environment. This theme encompasses (1) balancing positive and negative influences in the research process, (2) fostering transformational change for both nurses and patients, and (3) promoting complementary communication among nurses.

CONCLUSIONS

Clinical research plays a vital role in nursing practice that requires a balance of supportive elements, such as patient-driven research questions and hospital research support, with practical challenges such as shift work and high work intensity. This study found that a positive clinical nursing research culture can serve as a unifying bridge, connecting researchers, patients, who serve as both the origin and ultimate beneficiaries of research, and hospitals that facilitate research endeavors. Future research should explore whether the themes derived from this study fully reflect a clinical nursing research culture comprising patients, nurses, and the hospital environment and determine what requirements are needed to establish such a nursing research culture.
The International Market of Wheat and the Food Security
Authors: Petkov Vasil
Published: July 2023

The article reveals the situation at the international market of wheat in retrospective period with a stress on the previous three years. It examines the connections between the initial indicators such as production, consumption, export, import, stocks, etc. Derivative indicators are studied in order to find export orientation and import dependency at the wheat market. The ratio between the supply and the demand is calculated and the functioning of the market mechanism is explained. The balance method is applied which is very adequate for empirical proof of the interaction between supply, demand, and prices. The fluctuations of international prices of wheat are explained on the basis of the results from the calculations. The prices can be considered as one of the best indicator for studying and forecasting of the market situation. A short-term forecast for the future development of the market and market prices is prepared. The most vulnerable up-to-date issues of the food security are discussed and recommendations are made, because the agricultural products are very important for the life of human beings and are of great concern of the policy makers. The methodology, the research methods, and the results will enrich the existing knowledge in this sphere.
The Role of the Nurse in Hospital Care for Schizophrenia
Authors: - Anon
Published: July 2023

None
Marx Scientific and Technological Innovation Thought and Its Contemporary Enlightenment
Authors: Xie Kanglin
Published: July 2023

China’s economic and social development is inseparable from the development of science and technology, people are enjoying the convenience brought by science and technology, but also facing the problem between the application of science and technology and social development. Marx’s works contain a wealth of thought on scientific and technological innovation and are still of important value in the contemporary era, and provide an action guide for contemporary scientific and technological innovation, and maintain to guide our country’s science and technology development under the Marx thought of scientific and technological innovation, and provide the important practical significance to solve the problems facing our country’s science and technology development. It plays an important role in building a powerful nation of science and technology, and is conducive to promoting the sound development of science and technology undertakings. The current social development needs to increase the investment in science and technology. Based on the analysis from the perspective of development, advanced science and technology leads our country to constantly explore new fields, and mastering the core science and technology that has an important impact on the destiny of the country still has certain practical significance for the current construction of an innovation-oriented country.
IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITY OF MACRANGA PELTATA LEAF EXTRACTS ON LUNG CANCER CELL LINES
Authors: ANIL LINA , MOHANDAS S.
Published: July 2023

Objective: To determine the phytochemical constituents, antioxidant and anticancer activities of Macranga peltata leaf extracts on A549 and P 51 human lung cancer cell lines.

Methods: Leaf sample was subjected to soxhlet extraction method and phytochemical screening was done using different biochemical tests. The antioxidant activity was tested using 2,2–diphenyl-1-picrylhydrazyl, ferric ion reducing power assay and 2,2–azino bis 3–ethyl benzothiazoline–b–sulfonic acid assay. In vitro anticancer activity on A549 and P 51 human lung cancer cell lines was evaluated by (3-(4,5-dimethyl thiazole-2yl)-2,5–diphenyl tetrazolium bromide) MTT assay.

Results: Phytochemical screening confirmed the presence of phytoconstituents like tannins, flavanoids, alkaloids, saponins, glycosides and reducing sugar. The antioxidant assays exhibited significant inhibiting activity. MTT cell proliferation assay of methanolic extract of plant drug produced a cytotoxic effect on lung cancer cell lines A549 and P 51 with an IC50 value of 197.10 µg/ml, while it had no cytotoxic effect on normal cell lines.

Conclusion: It has been reported the effect of flavanoid characteristics in reducing the cancer. M. peltata contains a wide variety of secondary metabolites that hold strong antioxidant capacity. Their leaf have found to be potential source of antioxidants and anticancer activity.
AN OBSERVATIONAL STUDY OF EFFECT OF LABOUR INDUCTION ON MECONIUM ASPIRATION AND FOETAL OUTCOME
Authors: GUPTA RITU , TRIVEDI SWATI , GUPTA AYUSHI
Published: July 2023

Objective: Labor induction is a widely used procedure to initiate artificial uterine contractions, but its impact on meconium aspiration and fetal outcome needs further investigation, as meconium aspiration syndrome (MAS) poses significant risks to the newborn, including respiratory distress and other complications.

Methods: This prospective observational study evaluates labor induction and evaluate the occurrence of meconium aspiration and overall fetal outcomes. Data from a tertiary care hospital were analyzed, including mode of induction, gestational age, Bishop score, meconium-stained amniotic fluid, Apgar scores, NICU admissions, and other relevant parameters. Statistical analysis was conducted to identify significant associations.

Results: This observational study aimed to explore the relationship between labor induction and meconium aspiration, as well as their impact on fetal well-being. Data analysis identified correlations between labor induction techniques, meconium-stained amniotic fluid, and neonatal outcomes, offering valuable insights for clinical decision-making and optimizing fetal outcomes.

Conclusion: The impact of labor induction on meconium aspiration and fetal outcomes was investigated in this study, providing valuable insights for healthcare professionals and contributing to the improvement of safety guidelines for obstetric care.
COMPARING THE EFFICACY OF ROM EXERCISES WITH AND WITHOUT SCAPULAR MOBILIZATION IN PATIENTS WITH ADHESIVE CAPSULITIS
Authors: KHANDELWAL PINKY , KHAN JAFAR , P. T. RENUKA , KHAN USMAN
Published: July 2023

Objective: Adhesive capsulitis, or frozen shoulder, is a condition characterized by shoulder pain and limited range of motion. Its cause and pathophysiology are not well understood. The prevalence is estimated to range from 2% to 5% in the general population, with a higher incidence in women and individuals in their fifth and sixth decades of life. The optimal treatment approach for adhesive capsulitis is currently unclear, although ROM exercises are commonly prescribed. Scapular mobilization may enhance outcomes by addressing scapular dyskinesis and muscle imbalances.

Methods: A comparative study with 30 subjects diagnosed with adhesive capsulitis was conducted. Subjects were randomly assigned to two groups: ROM exercises with scapular mobilization (Group 1) and ROM exercises without scapular mobilization (Group 2). The study took place at PMCH, Udaipur, for 12 w, with sessions lasting 30 min per day, 5 d a week. Inclusion and exclusion criteria were established, and outcome measures such as pain scores, ROM measurements, functional assessments, and patient-reported outcomes were used.

Results: The analysis of SPADI scores revealed that Group A had a mean score of 41.73 (SD = 4.69, SE = 0.86), while Group B had a mean score of 42.40 (SD = 3.29, SE = 0.84), with a mean difference of 0.67. The t-test indicated a significant difference between the groups (t = 1.335, p = 0.021). Similarly, for VAS scores, Group A had a mean score of 3.20 (SD = 0.67, SE = 0.17), Group B had a mean score of 3.06 (SD = 0.70, SE = 0.18), with a mean difference of 0.14. The t-test also revealed a significant difference between the groups (t = 5.95, p = 0.038). These results demonstrate notable distinctions in both SPADI and VAS scores between Group A and Group B.

Conclusion: The study supports the effectiveness of combining scapular mobilization with ROM exercises for adhesive capsulitis. The group receiving both interventions showed greater improvements in shoulder range of motion and pain reduction compared to the ROM exercises alone group. Incorporating scapular mobilization into the treatment approach may enhance the management of adhesive capsulitis. Further research is needed to validate these findings and customize treatments based on individual patient characteristics.
A STUDY ON THE EFFECT OF ADDITIONAL BACKWARD WALKING TRAINING ON BALANCE AND FUNCTIONAL OUTCOMES IN PATIENTS WITH STROKE
Authors: KALYANA SHUBHAM , LOHAR DEEPAK , KHAN JAFAR , RAO LAKSHITA SINGH
Published: July 2023

Objective: Stroke is a significant cause of mortality and disability globally, with a higher prevalence in urban areas of India compared to rural regions. Men in India face a greater risk of stroke, attributed to factors such as smoking and drinking, which are more prevalent among Indian men. This study aimed to evaluate the influence of backward walking training on balance and functional outcomes in stroke patients.

Methods: Experimental Group received 30 min of backward walking training three times per week for three weeks. Balance was assessed using the Berg Balance Scale (BBS), and functional outcomes were measured using the Barthel Index (BI) before and after the intervention. Data analysis was performed using Student's paired t-test and unpaired t-test.

Results: Before the intervention, there were no significant differences between the Control Group and Experimental Group in terms of BBS and BI scores. However, after the intervention, the Experimental Group showed a significant improvement in both balance (BBS) and functional outcomes (BI) compared to the Control Group. The Experimental Group demonstrated a greater improvement in BI scores (9.94%) compared to the Control Group (4.95%), and a similar pattern was observed for BBS scores, with the Experimental Group showing a greater improvement (7.87%) compared to the Control Group (3.49%). These differences were statistically significant (p<0.01), indicating that the intervention in the Experimental Group was more effective than the Control Group.

Conclusion: These findings suggest that incorporating backward walking training into stroke rehabilitation programs can be beneficial for patients in terms of enhancing their balance and functional abilities.
COMPARING THE EFFICACY OF EARLY INTERVENTION AND LATE INTERVENTION FOR AUTISM SPECTRUM DISORDER IN CHILDREN AND ADULTS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: SANKHLA ANKIT , LOHAR DEEPAK , KHAN JAFAR , ARORA ABHISHEK
Published: July 2023

Objective: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by challenges in social interaction, communication, and repetitive behaviors. Early intervention is widely recognized as crucial for improving outcomes in individuals with ASD. However, there is ongoing debate regarding the optimal timing of intervention. This systematic review and meta-analysis aimed to compare the efficacy of early intervention and late intervention for individuals with ASD. The study aimed to synthesize existing evidence and provide a comprehensive analysis of the effectiveness of these two intervention approaches in improving outcomes for children and adults with ASD.

Methods: A comprehensive search of electronic databases was conducted to identify relevant studies. The search terms included keywords related to ASD, early intervention, late intervention, children, adults, and outcome measures. Studies were selected based on predefined inclusion and exclusion criteria, focusing on randomized controlled trials and comparative studies with adequate sample sizes. The selected studies underwent rigorous quality assessment and data extraction. Meta-analysis was conducted using statistical software to determine the overall efficacy of early intervention and late intervention in improving outcomes related to social interaction, communication, adaptive functioning, and other relevant domains.

Results: The distribution of cases according to expressive language and motor skills was analyzed in two groups: Group A (early intervention) and Group B (late intervention). The results showed no statistically significant differences in the distribution of cases according to expressive language and motor skills between the two groups. The findings suggested that the timing of intervention may not strongly influence the distribution of these skills in individuals with ASD.

Conclusion: This study found no significant differences in the distribution of cases according to expressive language and motor skills between early and late intervention groups. These findings are consistent with previous research, indicating that the distribution of these skills may not be strongly influenced by the timing of intervention. However, further research with larger samples and standardized assessment methods is needed to gain a comprehensive understanding of the relationships between intervention timing and the distribution of these skills in individuals with ASD.
The Impact of Environmental Changes and the Damage to the Structure of Beach Buildings in the Southeast Jazirah of Saparua Island, Central Maluku District
Authors: Serang Rudi
Published: July 2023

The coastal border is a certain area along the coast that has important benefits for maintaining the sustainability of coastal functions. The criterion for a coastal boundary is land along the edge whose width is in accordance with the shape and physical condition of the beach, at least 100 m from the highest tide point towards the mainland. Shoreline change is a series of coastal processes caused by external factors (currents, waves, winds and tides) and internal (characteristics and types of sediments and the base layer where the sediments are located). Shoreline changes will refer to sedimentary activity and deposition, namely the deposition of rock material that has been transported by hydropower or wind that occurs on the coast. The purpose of this paper is to determine environmental changes to coastal damage in the Southeastern Peninsula of Saparua Island and to analyze the damage to coastal structures that occurred in the Southeastern Peninsula of Saparua Island. The entire coastal building that was damaged by abrasion was the seawall. The benchmark for damage to the coastal environment from settlements and public facilities is with a weight of 200% and priority. While the agricultural area is with a weight of 100 and is less prioritized. Evaluation of the damage assessment of the coast of the Southeastern Peninsula which consists of 4 villages, namely Ouw Village, Ulath Village, Siri Sori Islam Village, and Siri Sori Serani Village with an importance weight coefficient of 1.00. The review was carried out based on the damage to the building that occurred, namely from STA 00+500 (with a building condition index of 3.4; Needs repair), STA 00+1500 (with a building condition index of 4; Heavily Damaged), STA 00+2000 (with a building condition index 3; Needs Repair), STA 00+3200 (with a building condition index of 3; Needs Repair), and STA 00+3600 (with a building condition index of 4; Heavily Damaged).
La ruta hacia el veganismo. Una aproximación desde los afectos a través de relatos de vida
Authors: Aguilera Bornand Isabel Margarita , Alfaro Juan , Giacoman Hernández Claudia Trinidad
Published: July 2023

Este artículo examina los inicios de trayectorias de vida veganas, siguiendo la perspectiva de Sara Ahmed respecto de la productividad social de las emociones. Nuestro objetivo es comprender cómo operan los afectos en el devenir vegano y para ello analizaremos relatos –recogidos mediante entrevistas con enfoque biográfico– sobre experiencias catalíticas y el contacto con animales durante la infancia de jóvenes veganos. En ambas instancias se observa que afectos como el miedo, la repugnancia y el amor se presentan simultáneamente, impulsando acciones de alejamiento y acercamiento, identificaciones y alterizaciones que configuran la experiencia. Sostendremos que las experiencias catalíticas corresponden a una toma de conciencia y a la búsqueda de consecuencia que descansa en el entrecruzamiento de emoción, sensación y cognición. Además, propondremos que el camino al veganismo se pavimenta de contactos e impresiones que marcan los cuerpos y resuenan en las trayectorias.
Reseña: Persistir, Reproducir, Jugar. Rodeo, vaquería y vaqueridad en la Baja California
Authors: Fernández Huerta Christian Alonso
Published: July 2023

La obra Persistir, reproducir, jugar. Rodeo, vaquería y vaqueridad en la Baja California es resultado de una investigación que no se limita a la escritura del libro, sino forma parte de un proyecto de doctorado, lo cual no es una empresa sencilla, cuyo resultado es una tesis. Un documento valioso en términos de generación de conocimiento, pero que a veces no es necesariamente el mejor vehículo para la divulgación de ese conocimiento. Así que surge una nueva labor: convertir la tesis en un texto que, sin perder el rigor científico y las bases teóricas, sea una contribución al campo del conocimiento y al mismo tiempo de fácil acceso a aquellos legos en el tema.
Potensi Kesulitan-Kesulitan Yang Dihadapi Siswa SMK Saat Menyelesaikan Masalah Materi Sistem Persamaan Linear Dua Variabel: Studi Eksploratif
Authors: Aprianti Desi , Nugroho Purna Bayu , Meilasari Venty
Published: July 2023

penelitian ini bertujuan untuk mengetahui kesulitan konsep dan prinsip yang dialami siswa dalam menyelesaikan soal cerita sistem persamaan linear dua variabel kelas X di SMK Muhammadiyah 1 Kotabumi dan faktor yang menyebabkan siswa mengalami kesulitan tersebut. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan bentuk studi kasus. Subjek yang digunakan dalam penelitian ini adalah beberapa siswa kelas X. Alat yang digunakan adalah ialah tes tertulis yang berbentuk essai. Dari analisis data diketahui kesulitan dan faktor penyebab kesulitan yang dialami siswa. Kesulitan memisalkan istilah variabel, kesulitan mengubah soal cerita kedalam kalimat matematika, kesulitan melakukan operasi dengan metode eliminasi dan substitusi, kesulitan mengoprasikan pengurangan dan penjumlahan, kesulitan mengubah nilai pengganti variabel ke dalam kalimat pertanyaan. Faktor penyebab kesulitan yakni kurangnya penguasaan materi SPLDV, kurangnya ketelitian saat pengerjaan soal, serta tidak menguasai konsep dan prinsip SPLDV.
Analysis of students' proportional reasoning in solving story problems
Authors: Husain Asrianti , Ikram Muhammad , Bahri Fahrul
Published: July 2023

Tujuan penelitian kualitatif ini adalah untuk menganalisis penalaran proporsional siswa dalam menyelesaikan soal cerita. Instrumen penelitian ini berupa lembar tugas penalaran proporsional materi perbandingan yang telah divalidasi. Subjek penelitian ini adalah siswa kelas VII SMP yang berjumlah 20 siswa. Prosedur pengumpulan data diawali dengan siswa mengerjakan instrumen penelitian untuk mengetahui kemampuan penalaran proporsional siswa. Setelah mengerjakan lembar tugas penalaran proporsional, wawancara dilakukan untuk mengetahui penalaran proporsional yang dimiliki siswa, kemudian dipilih 3 subjek penelitian untuk diwawancarai dengan tingkat penalaran proporsional yang memenuhi karakter yakni: (1) membangung hubungan antar kuantitas, (2) menuliskan kuantitas rasio untuk mempresentasikan masalah, (3) menstimulasikan untuk membuat hubungan multiplikatif; dan (4) mencari nilai yang tidak diketahui.Teknik analisis data dalam penelitian ini dilakukan dengan mentranskripkan data verbal yang dikumpulkan dan meninjau semua data yang tersedia dari berbagai sumber yaitu jawaban siswa, think alouds, dan wawancara. Hasil penelitian diperoleh 3 subjek dari kelas VII SMP menunjukkan bahwa dari deskripsi dan analisis subjek yang peneliti temukan adalah penalaran proporsional tipe holistik.
ISSUES OF SCIENTIFIC PRIORITY AGAINST THE BACKGROUND OF TWO PHILOSOPHICAL CONCEPTS OF SCIENTIFIC KNOWLEDGE
Authors: Krivchikov A. M.
Published: July 2023

The article explores 2 opposite approaches to the authorship of the special theory of relativity. The first assumes that Albert Einstein is the only scientist whose contribution to the development of science allowed the creation of SRT. The second approach proclaims that the theory of relativity is the product of the collective activity of many scientists who have been working on its creation for decades.
METAPHYSICAL STATUS OF PHYSICAL LAWS
Authors: Burov A. V. , Burov L. A. , Rybakova I. A.
Published: July 2023

The creators of physics sought to construct it like Euclidean geometry, where a few mathematically formulated axioms, laws, opens the possibility of an unlimited number of theorems, conclusions concerning specific situations, verified by special observations, experiments. The idea of this program of cognition, not necessarily quite consciously, arose from what may be called Biblical Platonism, a synthesis of the Pythagorean-Platonism of antiquity and Biblical cosmism. Explicitly or not, this program implied the following properties of the laws, the atemporal logical structure of the universe: sufficient mathematical simplicity, universality, absolute precision, completeness and compatibility with life and thought, and anthropicity. The subsequent development of physics has demonstrated both a truly cosmic success and certain problems and limits of this paradigm. The former manifested in the universality of coverage and the fantastic accuracy of the mathematically elegant laws of matter discovered. The latter were related to the dualism of mind and matter, the enigma of the emergence and development of life, the discovery of the limits to the applicability of theories, and the forced rejection of some self-evident truths that previously seemed immutable. The article outlines approaches to the solution of these problems, which seem to be compatible with biblical Platonism.
RELATIONAL SPACE AND TIME: METAPHYSICAL FOUNDATIONS AND POSSIBILITIES OF EXPERIMENTS
Authors: Aristov V. V.
Published: July 2023

Questions of a general philosophical, metaphysical nature about the properties of space and time inevitably intersect with their physical interpretation, including in hypothetical experiments. In this paper, relational ideas about the limiting philosophical categories are studied, which make it possible to concretize the ways of specifying space and time. This approach is compared with Leibniz’s concept. The development of relational theoretical propositions leads to predictions of new effects and a discussion of their possible experimental verifications. It is concluded that the foundations and future limits of the theory can, in a certain sense, be reconciled.
RANDOM HILBERT SPACE AND WIENER’S INTERPRETATION OF QUANTUM MECHANICS
Authors: Rybakov Yu. P.
Published: July 2023

The special representation of quantum mechanics suggested by Wiener is studied, the wave function being considered as Gaussian random variable, i. e. the vector of the random Hilbert space. The connection between this representation and the well-known Einstein’s program aiming at creating the consistent field formulation of particle physics is revealed, with particles being represented as solitons, clots of some material field satisfying nonlinear equations.
Air temperature changes due to altitude above sea level in the Northern Ural Mountains
Authors: Tantsyrev Nikolai V. , Ivanova Natalya S. , Petrova Irina V.
Published: July 2023

The research is devoted to an urgent modern problem: the identification of temperature factors that limit the distribution and survival of plants in the mountainous conditions of the Northern Urals. The article’s aim is to determine the air temperature in four altitudinal zones of the southern part of the Northern Urals (Sverdlovsk region 59º30´N, 59º15´E) and to identify regression relationships of the obtained temperature data with control temperature data from the nearest meteorological station. Registration of air temperatures was carried out from May to September 2019 around the clock, every two hours in the mountain forest zone (at an altitude of 460 and 640 m above sea level) under the canopy of Siberian stone pine forests, in the zone of subalpine woodlands with elements of mountain forest tundra (820 m above sea level) and on a plateau in the mountain tundra zone (1030 m above sea level). It has been established that the change in air temperature at different altitude levels and at the nearest meteorological station (far from 60 km, at an altitude of 202 m above sea level) occurs relatively synchronously. Difference between average daily temperatures at altitudes of 460, 640, 820 and 1030 m above sea level and the control data of the meteorological station is 2.2, 3.0, 4.7 and 5.1ºC respectively. For all altitude levels, a reliable close straight-line relationship between average daily air temperatures and meteorological station data has been established. The altitudes of 460, 640, 820 and 1030 m above sea level correspond to the coefficients of determination ( R 2) equal to 0.96, 0.95, 0.92 and 0.88. The relationship of the minimum temperatures of the corresponding altitude levels with the control data is also quite high ( R 2 is not lower than 0.7). With the help of the identified relationships and the obtained regression equations, it is possible to retrospectively restore the dynamics of the thermal regime according to the meteorological station data for mountain habitats of different altitudes in the southern part of the Northern Urals over a long period. Including extreme critical temperatures, which act as factors limiting the resettlement and survival of plants and determine the ecosystem biodiversity.
Methodological approaches to the electromagnetic radiation effects on microorganisms
Authors: Shcheglov Gleb A. , Masloboev Vladimir A.
Published: July 2023

All living organisms are surrounded by natural and artificial origin electromagnetic radiation (EMR), which affects organisms. The artificial radiation sources number is increasing, but the EMR influence mechanisms on living organisms have not yet been fully investigated, despite the large number of studies. However, understanding the EMR action mechanisms can give impetus to the development of various biotechnologies. To solve the problem of understanding the EMR effects on organisms and develop new biotechnologies, it is necessary to apply new research methods. Therefore, the study of research methods is an urgent task. This research is a review of studies and research methods on the effects, of EMR on organisms. It brings together studies that consider different approaches to the study and existing hypotheses of the mechanisms of radiation effects. The aim of the paper is to review and evaluate methodological approaches to investigate the effects of EMR. The paper considers research on the EMR effects on microorganisms, eubacteria. Based on the results of the work, it is proposed to study the effect of radiation lasting several hours. As well as to apply spectrophotometry and fluorimetry methods.
Comprehensive water quality assessment of surface sources in the city of Latacunga and the canton Pedro Vicente Maldonado in Ecuador
Authors: Salazar Flores Cristian A. , Kurbatova Anna I. , Mikhaylichenko Kseniya Y. , Barannikova Svetlana I.
Published: July 2023

A study of the quality of drinking water sources - surface waters of the river systems of the city of Latacunga and the canton of Pedro Vicente Maldonado, Ecuador, was carried out during 2018 and 2019. The general sanitary water quality index (WQI) was calculated according to Russian methods, the water quality index of the National Sanitation Foundation (NSF-WQI) of the Ecuadorian water quality regulation. Results from parameterizing the water quality, obtained by WQI and NSF-WQI methods and combined into an overall scheme, were used to generate the rating scale for assessing the hydro-ecological status of aquatic ecosystems. When carrying out a qualitative and quantitative analysis of water from river reservoirs, the excess of the threshold limit values of such indicators as the biological oxygen demand and iron was determined. The calculations show that the WQI method and the NSF-WQI method lead to similar results when assessing the water quality of both reservoir of the city of Latacunga and canton of Pedro Vicente Maldonado. According to the WQI method, the hydrological state of the reservoir of the city of Latacunga was characterized in the range of a scale from “Crisis” to “Risk”, while according to the NSF-WQI method the state was assessed as “Risk”. The hydrological state of the reservoir of the canton of Pedro Vicente Maldonado, was assessed as “Risk” by both the WQI method and the NSF-WQI method. Furthermore, in none of the water bodies under study is the environmental “catastrophe” not recorded.
Questions of accumulated environmental harm - People’s Republic of China
Authors: Zhang Xuecong , Pinaev Vladimir E.
Published: July 2023

The research is dedicated to the state of legislation in the People's Republic of China on accumulated environmental harm and existing practices of liquidating objects of accumulated environmental harm. This research contains an up-to-date list of regulatory legal documents of the People’s Republic of China on the topic. The research also presents some aspects of Chinese scientists’ research on environmental impact and accumulated environmental harm.
Reuse of concrete and brick scrap as aggregates
Authors: Ukrainskiy Ilya S. , Mayorova Lyudmila P. , Salikov Denis A. , Shevchuk Alexandr S. , Chainikov Gleb A.
Published: July 2023

The use of industrial waste as concrete aggregates solves the problem of recycling these wastes and simultaneously reduces the volume of natural stone materials extraction and, consequently, decreases the environment load associated with their extraction. The special military operation caused a large amount of concrete and brick scrap from the emergency buildings demolition. To substantiate the possibility of recycling the mentioned construction wastes by means of their application as concrete aggregates, the authors have reviewed research works in this area, made a plan of the experiment, determined physical and mechanical characteristics of rubble from the studied materials and cement concrete on its basis. The results of the experiment have been analyzed and conclusions about possibility to use concrete and bricks scrap as aggregates in concrete have been formulated.
ANALISIS PENGARUH PENGELUARAN PEMERINTAH TERHADAP KEMISKINAN DI PROVINSI BENGKULU
Authors: Septriani Septriani
Published: July 2023

Penelitian ini bertujuan untuk menganalisis pengaruh belanja fungsi kesehatan, belanja fungsi pendidikan, dan belanja perlindungan social  terhadap kemiskinan pada kabupaten/kota di Provinsi Bengkulu. Penelitian ini menggunakan data sekunder yang diambil dari Kementerian Keuangan dan Badan Pusat Statistik. Adapun alat analisis yang digunakan adalah analisis regresi data panel. Berdasarkan hasil regresi data panel, diperoleh  random effect model sebagai model terbaik. Berdasarkan uji t diperoleh hasil bahwa secara parsial belanja fungsi kesehatan berpengaruh negatif dan signifikan terhadap kemiskinan pada α (0,05), kemudian belanja fungsi pendidikan berpengaruh positif dan signifikan terhadap kemiskinan pada α (0,05), sedangkan belanja perlindungan social   tidak berpengaruh terahadap kemiskinan. Kemudian secara simultan variabel belanja fungsi kesehatan, belanja fungsi pendidikan, dan belanja fungsi perlindungan social  berpengaruh positif dan signifikan terhadap kemiskinan pada α (0,05) dengan hasil nilai Adjusted R-square sebesar 0.3318 atau sebesar 33,18 persen. Artinya pada penelitian ini masih banyak variabel di luar model yang mempengaruhi kemiskinan. Pada penelitian ini ditemukan bahwa program pemerintah daerah dalam belanja fungsi kesehatan dan belanja fungsi pendidikan telah memberikan dampak yang signifikan terhadap kemiskinan di Provinsi Bengkulu. Sementara belanja fungsi perlindungan social tidak berdampak pada kemiskinan di Provinsi Bengkulu. Oleh kerena itu, pemerintah daerah dapat meningkatkan belanja fungsi kesehatan dalam upaya pengentasan kemiskinan di Provinsi Bengkulu, sementara untuk belanja fungsi pendidikan, pemerintah daerah Provinsi Bengkulu perlu mengalokasikan anggaran untuk program yang tepat sehingga mampu meningkatkan kualitas pendidikan. Sedangkan pada belanja fungsi perlindungan social, pemerintah daerah Provinsi Bengkulu perlu membuat program yang bersifat mitigasi jangka panjang dan pengawasan yang ketat dalam pemberian bantuan social kepada masyarakat, sehingga akan memberikan dampak yang signifikan dalam pengentasan kemiskinan di Provinsi Bengkulu.
Proximidad al estudio del dominio «Raíces y tubérculos» mediante la base de datos Alianza de Servicios de Información Agropecuaria (SIDALC) en el período del 2000 al 2020
Authors: Jiménez-Zúñiga Marcela
Published: July 2023

La temática raíces y tubérculos, en el período del 2000 al 2020, se describe mediante un análisis de dominio, en la base de datos Alianza de Servicios de Información Agropecuaria (SIDALC). Al ser un grupo alimentario de suma importancia para las poblaciones rurales de América, las raíces y tubérculos fueron de interés para los resultados que se obtuvieron en este artículo. Se investigó acerca de la bibliometría, análisis bibliométricos y del dominio, con el uso de fuente secundaria esa base de datos y se determinaron dos tipos de indicadores bibliométricos: los unidimensionales y los multidimensionales. El alcance fue descriptivo, con un análisis mixto. De las relaciones estructurales de las instituciones científicas, se obtuvo un alto índice de coautoría que demostró una alta colaboración en los resultados científicos. El análisis efectuado permitió una proximidad a la relevancia del dominio raíces y tubérculos en América. Se resaltó la importancia que tienen las temáticas de la ciencia de los alimentos, al ser un eje fundamental de las políticas de seguridad alimentaria en los países de este continente.
Leverage Biology to Learn Rapidly from Mistakes without Feeling like a Failure
Authors: Margulieux Lauren , Prather James , Rahimi Masoumeh , Uzun Gozde Cetin
Published: July 2023

Our biology affects how we interact with the world, including how we learn new knowledge and respond to challenges. This article explores the impact of neurochemicals in our brain on learning and explains how to leverage our biology to improve education and problem-solving, focusing on computing education. Within this context, the article particularly examines the role of failure while learning. Learning, especially in technical fields, includes making errors on the path to success. While these errors trigger the necessary neurochemical conditions for rapid learning, these failures can also be demotivating. To gain the benefits of failure while mitigating its negative consequences, this article recommends evidence-based behavioral strategies for making the best out of failing while learning and designing for failure in learning environments.
Blind Demodulation Algorithm for Short Burst FM-MFSK Based on STFT
Authors: gao chunfang , Lee ChoongHyun , Wei Xiaoji , Gong Yong
Published: July 2023

With the increasing innovation of network communication technology,
short burst communication has been developed to a certain extent in the
time compression technology, which brings great challenges to the radio
signal blind reception technology .In the blind reception of
non-cooperative signals in short-time burst communication, signal time
domain detection is the premise and key of signal modulation parameter
estimation, signal demodulation, decoding, interpretation, information
acquisition and interference guidance. In this paper, the blind
demodulation method of short-time burst FM-MFSK signal is studied under
the condition of low signal-to-noise ratio. A short-time burst FM-MFSK
blind demodulation method based on STFT is proposed. When SNR is higher
than 2dB, the correct demodulation probability for FM-MFSK signal can
reach 90%.
Seroprevalence of SARS-COV-2 infection in the general population of Nepal during the first and second generalized waves of the COVID-19 pandemic -2020-2021
Authors: Paudel Krishna , Samuel Reuben , Jha Runa , Pandey Basudev , Edirisuriya Chathura , Shrestha Nebin , Gyawali Pradip , Pokhrel Amrit , Shrestha Lilee , Mahato Ram , Hossain Shaik , Arunkumar Govindakarnavar , Bose Anindya , Dhimal Meghnath , Gautam Dipendra , Neupane Subash , Thakur Nishant , Shrestha Saugat , Bhusal Nirajan , Jha Priya , Gupta Binod , Rayamajhi Rajan , Subedee Koshal , Kandel Shashi , Poudel Mukesh , Thapa Lila , Sharma Guna , Gocotano Allison , Sunny Avinash , Gautam Rabin , Bhatta Deepak , Awal Balkrishna , Rokha Bhola , Ohja Hemant , Baral Phanindra , Adhikari Mahendra , Lohani Guna , Shrestha Mahendra , Singh Dipendra , Vandelaer Jos , Aryal Laxman , Pandav Rajesh , Pokhrel Roshan
Published: July 2023

Few seroprevalence studies were performed on coronavirus disease
(COVID-19) in Nepal. Here, we aimed to estimate seroprevalence and
assess risk factors for infection in the general population of Nepal by
conducting two rounds of sampling. The first round in October 2020 at
the peak of the first generalized wave of COVID-19 and the second round
in July-August 2021 following the peak of the wave caused by the delta
variant of SARS-COV-2. We used cross-sectional probability-to-size
(PPS)-based multistage cluster sampling to estimate the seroprevalence
in the general population of Nepal at the national and provincial
levels. We tested for the presence of anti-SARS-CoV-2 total antibody
using the WANTAI SARS-CoV-2 Ab ELISA kit. In Round 1, the overall
national seroprevalence was 14.4%, with provincial estimates ranging
from 5.3% in Sudurpaschim to 27.3% in Madesh province. In Round 2, the
estimated national seroprevalence was 70.7%, with the highest estimated
seroprevalence in Madesh Province (84.8%) and the lowest in the Gandaki
Province (62.9%). Seroprevalence was comparable between males and
females (Round 1, 15.8% vs 12.2% and Round 2, 72.3% vs. 68.7%). The
seroprevalence in the ecozones—terai, hills, and mountains—was
76.3%, 65.3%, and 60.5% in Round 2 and 17.7%, 11.7%, and 4.6% in
Round 1, respectively. In Nepal, COVID-19 vaccination was introduced in
January, 2021. At the peak of the first generalized wave of COVID-19,
most of the population of Nepal remained unexposed to SARS-COV-2 and
towards the end of the second generalized wave in April 2021, two-thirds
of the population was exposed.
“An unusual case of diffuse cystic lung disease: A teenager with lung metastasis”
Authors: Guler Sevim , NC Hull , Arteta Manuel , Demirel Nadir
Published: July 2023

We are presenting a teenage girl with a recent history of virilism who
presented with tension pneumothorax. Subsequent contrast-enhanced chest
CT revealed multiple bilateral irregular thin-walled cysts of varying
sizes with numerous solid noncalcified pulmonary nodules and pulmonary
artery pseudoaneurysms. Lung biopsy revealed trophoblastic neoplasm with
metastasis to both lungs. We discussed the differential diagnosis of
diffuse cystic lung diseases. While diffuse cystic lung diseases in
children are rarely due to malignancy, we emphasize that clinicians be
aware of the possibility of metastatic lung diseases and their
radiologic features when encountering diffuse cystic lung diseases.
Additively manufactured microhelix motors' bursting motion in mesoscopic tubes for declogging
Authors: Cao Yang , Yi Hongyu , Ge Kongyu , Zhan Limeng , Gao Yifan , Zhang Zhenchao , feng huanhuan
Published: July 2023

Magnetic microhelix motors have been widely used in many fields such as
cargo transportation, drug delivery, toxic substance declogging and cell
manipulation due to their unique adaptive magnetic manipulation. In this
work, we have additively manufactured microhelices with different
circles, sizes and angles (circles 2-4, size 100 μm-250 μm and angle
174°-180°) and systematically investigated their motion performance
under magnetic field, especially their motion bursting in mesoscopic
tubes. We found that their speed increase from 0.04 mm/s to 0.08 mm/s
when their circle numbers decrease from 4 to 3. Their speed continue
increasing from 0.08 mm/s to 0.09 mm/s, while their circle diameter
increase from 100 μm to 250 μm. Their speed will continue increase
significantly from 0.08 mm/s to 0.11 mm/s when their taper angle
decrease from 180° to 172°. The magnetic microhelix motors’ speed
continued increase significantly from 0.11 mm/s to 0.17 mm/s, when they
are in mesoscopic tubes while the tubes diameter reduced from 0.6 mm to
0.3 mm. In summary, our microhelix motors’ speed can be bursted from
0.04 mm/s to 0.17 mm/s via internal microstructure variation and
external mesoscopic circumstance. We have successfully conducted vessel
declogging experiments within mesoscopic tubes, and our microhelix
motors are capable of declogging clot out of mesoscopic tubes. We
believe that it is very promising for vessel declogging in vitro and
hold great potential for declogging thrombus in vivo.