bluuebunny/crossref_metadata_2025 huggingface dataset:
Social preference is maintained in mice with impaired startle reflex and glutamate/D-serine imbalance induced by chronic cerebral toxoplasmosis
Authors: Acquarone Mariana , Poleto A. , Perozzo A. F. , Gonçalves P. F. R. , Panizzutti R. , Menezes J. R. L. , Neves G. A. , Barbosa Helene Santos
Published: July 2021

Toxoplasma gondii is an opportunistic protozoan pathogen with a wide geographic distribution. The chronic phase of toxoplasmosis is often asymptomatic in humans and is characterized by tissue cysts throughout the central nervous system and muscle cells. T. gondii and other pathogens with tropism for the central nervous system are considered risk factors in the etiology of several neuropsychiatric disorders, such as schizophrenia and bipolar disorder, besides neurological diseases. Currently, it is known that cerebral toxoplasmosis increases dopamine levels in the brain and it is related to behavioral changes in animals and humans. Here we evaluate whether chronic T. gondii infection, using the cystogenic ME-49 strain, could induce behavioral alterations associated with neuropsychiatric disorders and glutamatergic neurotransmission dysfunction. We observed that the startle amplitude is reduced in the infected animals as well as glutamate and D-serine levels in prefrontal cortical and hippocampal tissue homogenates. Moreover, we did not detect alterations in social preference and spontaneous alternation despite severe motor impairment. Thus, we conclude that behavioral and cognitive aspects are maintained even though severe neural damage is observed by chronic infection of C57Bl/6 mice with the ME-49 strain.
Influence of synthesis parameters on crystallization behavior and ionic conductivity of the Li4PS4I solid electrolyte
Authors: Strauss Florian , Lin Jing , Janek Jürgen , Brezesinski Torsten
Published: July 2021

Superionic solid electrolytes are key to the development of advanced solid-state Li batteries. In recent years, various materials have been discovered, with ionic conductivities approaching or even exceeding those of carbonate-based liquid electrolytes used in high-performance Li-ion batteries. Among the different classes of inorganic solid electrolytes under study, lithium thiophosphates are one of the most promising due to their high Li-ion conductivity at room temperature and mechanical softness. Here, we report about the effect of synthesis parameters on the crystallization behavior and charge-transport properties of Li4PS4I. We show that thermally induced crystallization of Li4PS4I (P4/nmm), starting from the glassy phase 1.5Li2S–0.5P2S5–LiI, adversely affects the material’s conductivity. However, both conductivity and crystallization temperature can be significantly increased by applying pressure during the preparation.
Comparison of retrograde intrarenal surgery and standard percutaneous nephrolithotomy for management of stones at ureteropelvic junction with high-grade hydronephrosis
Authors: Wang Fang , Hong Yun , Yang Zesong , Ye Liefu
Published: July 2021

Percutaneous nephrostomy (PCNL) and retrograde intrarenal surgery (RIRS) are the two main treatments for upper urinary tract stones. The aim of our study was to compare the effectiveness and safety of standard PCNL (S-PCNL) and RIRS for the treatment of stones at ureteropelvic junction with high-grade hydronephrosis. The study included 118 patients who underwent surgery for stones at ureteropelvic junction. S-PCNL and RIRS were performed on 66 and 52 patients, respectively. Patient age, sex, body mass index (BMI), stone side, history of urinary tract infection (UTI), history of diabetes, history of ESWL, stone size, Hounsfield unit (HU) values of stones, grade of hydronephrosis, operating time, postoperative hemoglobin loss, narcotic analgesic use, postoperative transfusion rates, stone-free rates (SFRs), length of hospital stay, complication rates and number of secondary interventions were recorded. The comparison of the operative data between the two groups revealed no statistically significant differences in the operative time, SFRs, narcotic analgesic use, postoperative transfusion rate or other postoperative complications defined according to the Clavien system (P > 0.05). The postoperative urinary sepsis rate in the RIRS group was as high as 15.4%, which was much higher than the 1.5% rate observed in the S-PCNL group, and the difference was statistically significant (P < 0.05). A total of 13.5% of the patients in the RIRS group required a second operation due to failure of the placement of the ureteral access sheath. Additionally, S-PCNL had an advantage in operation time, while RIRS in duration of hospital stay and postoperative hemoglobin loss. RIRS and S-PCNL were safe and effective methods for the treatment of stones at ureteropelvic junction with high-grade hydronephrosis. Importantly, S-PCNL had more advantages in terms of the postoperative urinary sepsis rate and secondary surgery rate.
Calmodulin-dependent KCNE4 dimerization controls membrane targeting
Authors: Roig Sara R. , Solé Laura , Cassinelli Silvia , Colomer-Molera Magalí , Sastre Daniel , Serrano-Novillo Clara , Serrano-Albarrás Antonio , Lillo M. Pilar , Tamkun Michael M. , Felipe Antonio
Published: July 2021

The voltage-dependent potassium channel Kv1.3 participates in the immune response. Kv1.3 is essential in different cellular functions, such as proliferation, activation and apoptosis. Because aberrant expression of Kv1.3 is linked to autoimmune diseases, fine-tuning its function is crucial for leukocyte physiology. Regulatory KCNE subunits are expressed in the immune system, and KCNE4 specifically tightly regulates Kv1.3. KCNE4 modulates Kv1.3 currents slowing activation, accelerating inactivation and retaining the channel at the endoplasmic reticulum (ER), thereby altering its membrane localization. In addition, KCNE4 genomic variants are associated with immune pathologies. Therefore, an in-depth knowledge of KCNE4 function is extremely relevant for understanding immune system physiology. We demonstrate that KCNE4 dimerizes, which is unique among KCNE regulatory peptide family members. Furthermore, the juxtamembrane tetraleucine carboxyl-terminal domain of KCNE4 is a structural platform in which Kv1.3, Ca2+/calmodulin (CaM) and dimerizing KCNE4 compete for multiple interaction partners. CaM-dependent KCNE4 dimerization controls KCNE4 membrane targeting and modulates its interaction with Kv1.3. KCNE4, which is highly retained at the ER, contains an important ER retention motif near the tetraleucine motif. Upon escaping the ER in a CaM-dependent pattern, KCNE4 follows a COP-II-dependent forward trafficking mechanism. Therefore, CaM, an essential signaling molecule that controls the dimerization and membrane targeting of KCNE4, modulates the KCNE4-dependent regulation of Kv1.3, which in turn fine-tunes leukocyte physiology.
Drying and temperature induced conformational changes of nucleic acids and stallion sperm chromatin in trehalose preservation formulations
Authors: Brogna Raffaele , Fan Juezhu , Sieme Harald , Wolkers Willem F. , Oldenhof Harriëtte
Published: July 2021

Even though dried sperm is not viable, it can be used for fertilization as long as its chromatin remains intact. In this study, we investigated drying- and temperature-induced conformational changes of nucleic acids and stallion sperm chromatin. Sperm was diluted in preservation formulations with and without sugar/albumin and subjected to convective drying at elevated temperatures on glass substrates. Accumulation of reactive oxygen species was studied during storage at different temperatures, and the sperm chromatin structure assay was used to assess DNA damage. Fourier transform infrared spectroscopy was used to identify dehydration and storage induced conformational changes in isolated DNA and sperm chromatin. Furthermore, hydrogen bonding in the preservation solutions associated with storage stability were investigated. Reactive oxygen species and DNA damage in dried sperm samples were found to accumulate with increasing storage temperature and storage duration. Non-reducing disaccharides (i.e., trehalose, sucrose) and albumin counteracted oxidative stress and preserved sperm chromatin during dried storage, whereas glucose increased DNA damage during storage. When sperm was dried in the presence of trehalose and albumin, no spectral changes were detected during storage at refrigeration temperatures, whereas under accelerated aging conditions, i.e., storage at 37 °C, spectral changes were detected indicating alterations in sperm chromatin structure.
Endothelial cell-derived Apelin inhibits tumor growth by altering immune cell localization
Authors: Hu Liuying , Hayashi Yumiko , Kidoya Hiroyasu , Takakura Nobuyuki
Published: July 2021

The Apelin/APJ signalling pathway, involved in multiple physiological and pathological processes, has been attracting increasing interest recently. In our previous study, Apelin overexpression in colon26 tumor cells suppressed tumor growth by inducing vascular maturation. Here, we found that MC38 and LLC tumor growth were greater in the absence of Apelin than in wild-type (WT) mice, suggesting that Apelin acts as a tumor suppressor. Consistent with this, treating WT mice with [Pyr1]Apelin-13 inhibited tumor growth. In MC38 tumors, only endothelial cells (ECs) strongly express APJ, a cognate receptor for Apelin, indicating that EC-derived Apelin might regulate tumor formation in an autocrine manner. Comparing with WT mice, larger numbers of vessels with narrower diameters were observed in tumors of Apelin knockout mice and lack of Apelin enhanced tumor hypoxia. Investigating immune cells in the tumor revealed that [Pyr1]Apelin-13 infusion induced the accumulation of CD8+ and CD4+ T cells in central areas. Moreover, RNA-sequencing analysis showed that Apelin induces chemokine CCL8 expression in ECs. Thus, enhancing anti-tumor immunity might be one of the mechanisms by which Apelin is involved in tumor growth. Our result indicated that increased CCL8 expression might induce CD8 +  T cells infiltration into tumor and tumor inhibition.
Coating matching recommendation based on improved fuzzy comprehensive evaluation and collaborative filtering algorithm
Authors: Xin Yuan , Henan Bu , Jianmin Niu , Wenjuan Yu , Honggen Zhou , Xingyu Ji , Pengfei Ye
Published: July 2021

Coating matching design is one of the important parts of ship coating process design. The selection of coating matching is influenced by various factors such as marine corrosive environment, anti-corrosion period and working conditions. There are also differences in the coating performance requirements for different ship types and different coating parts. At present, the design of coating matching in shipyards depends on the experience of technologist, which is not conducive to the scientific management of ship painting process and the macro control of ship construction cost. Therefore, this paper proposes a hybrid algorithm of fuzzy comprehensive evaluation and collaborative filtering based on user label improvement (IFCE-CF). Based on the analytic hierarchy process (AHP), the evaluation index system of coating matching is constructed, and the weight calculation process of fuzzy comprehensive evaluation is optimized by introducing the user label weight. The collaborative filtering algorithm based on matrix decomposition is used to realize the accurate recommendation of coating matching. Historical coating process data of a shipyard between 2010 and 2020 are selected to verify the recommendation ability of the method in the paper. The results show that using the coating matching intelligent recommendation algorithm proposed in this paper, the root mean square error is < 1.02 and the mean absolute error is < 0.75, the prediction accuracy is significantly better than other research methods, which proves the effectiveness of the method.
Testing the foundation of quantum physics in space via Interferometric and non-interferometric experiments with mesoscopic nanoparticles
Authors: Gasbarri Giulio , Belenchia Alessio , Carlesso Matteo , Donadi Sandro , Bassi Angelo , Kaltenbaek Rainer , Paternostro Mauro , Ulbricht Hendrik
Published: July 2021

Quantum technologies are opening novel avenues for applied and fundamental science at an impressive pace. In this perspective article, we focus on the promises coming from the combination of quantum technologies and space science to test the very foundations of quantum physics and, possibly, new physics. In particular, we survey the field of mesoscopic superpositions of nanoparticles and the potential of interferometric and non-interferometric experiments in space for the investigation of the superposition principle of quantum mechanics and the quantum-to-classical transition. We delve into the possibilities offered by the state-of-the-art of nanoparticle physics projected in the space environment and discuss the numerous challenges, and the corresponding potential advancements, that the space environment presents. In doing this, we also offer an ab-initio estimate of the potential of space-based interferometry with some of the largest systems ever considered and show that there is room for tests of quantum mechanics at an unprecedented level of detail.
A hydrogel-based implantable multidrug antitubercular formulation outperforms oral delivery
Authors: Pal Sanjay , Soni Vijay , Kumar Sandeep , Jha Somesh Kumar , Medatwal Nihal , Rana Kajal , Yadav Poonam , Mehta Devashish , Jain Dolly , Sharma Pankaj , Kar Raunak , Srivastava Aasheesh , Patil Veena S. , Dasgupta Ujjaini , Nandicoori Vinay Kumar , Bajaj Avinash
Published: July 2021

We showed that hydrogel-mediated delivery of a combination of anti-tuberculosis drugs is more effective than oral delivery against tuberculosis.
Origin determination of the Eastern oyster (Crassostrea virginica) using a combination of whole-body compound-specific isotope analysis and heavy metal analysis
Authors: Matos Mayara P. V. , Engel Marc E. , Mangrum John B. , Jackson Glen P.
Published: July 2021

A combination of amino-acid-specific isotope ratio mass spectrometry and ICP-MS of lead and cadmium helped discriminate the harvesting areas of the Eastern oyster, Crassostrea virginica, within the Gulf of Mexico.
One-pot fructose conversion into 5-ethoxymethylfurfural using a sulfonated hydrophobic mesoporous organic polymer as a highly active and stable heterogeneous catalyst
Authors: Manjunathan Pandian , Upare Pravin P. , Lee Maeum , Hwang Dong Won
Published: July 2021

We report a sulfonated hydrophobic mesoporous organic polymer (MOP-SO3H) as a highly efficient heterogeneous catalyst for one-pot 5-ethoxymethylfurfural (EMF) production from fructose in ethanol solvent.
Decoupled electrochemical water-splitting systems: a review and perspective
Authors: Ifkovits Zachary P. , Evans Jake M. , Meier Madeline C. , Papadantonakis Kimberly M. , Lewis Nathan S.
Published: July 2021

Decoupled electrochemical water splitting systems separate the hydrogen- and oxygen-evolution reactions spatially, temporally, or both, resulting in modular, flexible, and intrinsically safe electrolysis.
Additive stabilization of SEI on graphite observed using cryo-electron microscopy
Authors: Han Bing , Zou Yucheng , Xu Guiyin , Hu Shiguang , Kang Yuanyuan , Qian Yunxian , Wu Jing , Ma Xiaomin , Yao Jianquan , Li Tengteng , Zhang Zhen , Meng Hong , Wang Hong , Deng Yonghong , Li Ju , Gu Meng
Published: July 2021

Cryo-electron microscopy study finds that EC-based electrolyte can exfoliate the graphite surface and destabilize the SEI. Useful additives including FEC, DTD, TPP, and VC can form a stable SEI to protect the graphite anode.
Edible mushroom consumption and incident hyperuricemia: results from the TCLSIH cohort study
Authors: Zhang Tingjing , Rayamajhi Sabina , Meng Ge , Zhang Qing , Liu Li , Wu Hongmei , Gu Yeqing , Wang Yawen , Zhang Shunming , Wang Xuena , Zhang Juanjuan , Li Huiping , Thapa Amrish , Sun Shaomei , Wang Xing , Zhou Ming , Jia Qiyu , Song Kun , Niu Kaijun
Published: July 2021

The association between energy-adjusted mushroom consumption and hyperuricemia was examined using restricted cubic splines (RCS) with three knots.
Structural characteristics of Gracilaria lemaneiformis oligosaccharides and their alleviation of dextran sulphate sodium-induced colitis by modulating the gut microbiota and intestinal metabolites in mice
Authors: Xie Xu-Ting , Zheng Li-Xin , Duan Hui-Min , Liu Yang , Chen Xian-Qiang , Cheong Kit-Leong
Published: July 2021

G. lemaneiformis oligosaccharides alleviate sodium dextran sulfonate-induced colitis by regulating intestinal flora and intestinal metabolites in mice.
Malvidin and its derivatives exhibit antioxidant properties by inhibiting MAPK signaling pathways to reduce endoplasmic reticulum stress in ARPE-19 cells
Authors: Liu Xinyao , Zheng Fei , Li Sheng , Wang Zhitong , Wang Xinyuan , Wen Liankui , He Yang
Published: July 2021

Diagram of the molecular mechanism of MV, Mv3C, and Mv3ACEC protecting ARPE-19 cells against oxidative stress.
Zinc delivery system constructed from food-borne nanoparticles derived from Undaria pinnatifida
Authors: Qiao Fengzhi , Yu Xiaoting , Tie Shanshan , Chen Yannan , Hou Shuai , Tan Mingqian
Published: July 2021

Food-borne nanoparticles from Undaria pinnatifida (UPFNs) were prepared and successfully applied as nanocarriers for microelement zinc delivery.
New perspectives in cancer drug development: computational advances with an eye to design
Authors: Castelli Matteo , Serapian Stefano A. , Marchetti Filippo , Triveri Alice , Pirota Valentina , Torielli Luca , Collina Simona , Doria Filippo , Freccero Mauro , Colombo Giorgio
Published: July 2021

Allosteric and cryptic pockets are emerging as promising targets to develop strategies expanding the chemical space of new drug candidates. Innovative computational methods play a key role in their discovery.
Mechanistic process understanding of the self-assembling behaviour of asymmetric bolaamphiphilic short-peptides and their templating for silica and titania nanomaterials
Authors: Wang Shengjie , Liu Fangyuan , Ma Ning , Li Yanpeng , Jing Qian , Zhou Xinming , Xia Yongqing
Published: July 2021

Self-assembled nanostructures of asymmetric bolaamphiphilic peptides with tunable morphologies and switchable surficial properties can be obtained, which can be used as templates for inorganic nanostructures such as silica and titania.
The interactions of folate with the enzyme furin: a computational study
Authors: Sheybani Zahra , Heydari Dokoohaki Maryam , Negahdaripour Manica , Dehdashti Mehdi , Zolghadr Hassan , Moghadami Mohsen , Masoompour Seyed Masoom , Zolghadr Amin Reza
Published: July 2021

The present study introduces the ability of folic acid to interact and inhibit furin proprotein.
Experimental design approaches to optimize ultrasound-assisted simultaneous-silylation dispersive liquid–liquid microextraction for the rapid determination of parabens in water samples
Authors: Hsieh Chi-Zhong , Chung Wu-Hsun , Ding Wang-Hsien
Published: July 2021

This work describes a rapid solvent-minimized process to effectively determine four common paraben preservatives (methyl-, ethyl-, propyl- and butyl-paraben) in surface water samples.
Structural diversity in the coordination compounds of cobalt, nickel and copper with N-alkylglycinates: crystallographic and ESR study in the solid state
Authors: Vušak Darko , Smrečki Neven , Muratović Senada , Žilić Dijana , Prugovečki Biserka , Matković-Čalogović Dubravka
Published: July 2021

Interactions in copper, nickel and cobalt complexes with N-methyl-, N-ethyl- and N-propylglycinate: monomers, dimer and polymers.
Sulfur stereogenic centers in transition-metal-catalyzed asymmetric C–H functionalization: generation and utilization
Authors: Liu Wentan , Ke Jie , He Chuan
Published: July 2021

This perspective highlights sulfur functional groups enabled enantioselective C–H functionalization for the construction of sulfur stereogenic centers, and the utilization of chiral sulfoxide to realize stereoselective C–H functionalization.
Synthesis of a carborane-substituted bis(phosphanido) cobaltate(i), ligand substitution, and unusual P4fragmentation
Authors: Coburger Peter , Leitl Julia , Scott Daniel J. , Hierlmeier Gabriele , Shenderovich Ilya G. , Hey-Hawkins Evamarie , Wolf Robert
Published: July 2021

Cobalt and nickel complexes of a new carborane-substituted bis(phosphanido) ligand have been prepared. Reaction of the cobalt complex with white phosphorus (P4) results in a remarkable fragmentation of P4into P3and P1units.
Hydroxyl improving the activity, selectivity and stability of supported Ni single atoms for selective semi-hydrogenation
Authors: Jian Minzhen , Liu Jin-Xun , Li Wei-Xue
Published: July 2021

Hydroxyl group can stabilize significantly Ni single atom by forming Ni1(OH)2 complexes on anatase TiO2(101), which displays high catalytic performance in acetylene semi-hydrogenation.
Affine projection Weibull M‐transform least mean square algorithm against impulsive interference
Authors: Liu Pingchuan , Fan Kuangang , Qiu Haiyun
Published: July 2021

The well‐known affine projection sign algorithm is one of the classic adaptive filtering methods for denoising and channel equalisation, which can achieve robust performance against coloured input and impulse noise. This work proposes the affine projection Weibull M‐transform least mean square algorithm to improve the steady‐state performance of affine projection algorithms. The proposed algorithm combines the Weibull M‐transform cost function with the L2‐norm constraint of weight vector to improve the performance of existing affine projection algorithms and achieve a better convergence rate and better misalignment. This novel algorithm also preserves good performance against impulsive interference and coloured input. Simulation results demonstrated that the proposed algorithm has a remarkable improvement in convergence performance compared with other algorithms.
A deep learning method for video‐based action recognition
Authors: Zhang Guanwen , Rao Yukun , Wang Changhao , Zhou Wei , Ji Xiangyang
Published: July 2021

In this paper, a deep learning method for video‐based action recognition is proposed. On the one hand, boundary compensation on the basis of a deep neural network is performed to achieve action proposal. Boundary compensation considering non‐maximum suppression according to sliding window priority is applied to remove redundant windows. To accurately detect boundaries, a boundary compensation network is established with multiple networks to process different numbers of segments. On the other hand, action recognition based on the resultant action proposals is performed. To further utilise boundary compensation, three methods are introduced for key frame selection. Optical flow and RGB features are combined via a channel fusion to realise feature representation. A two‐stream network with a spatiotemporal structure is adopted for action recognition. The proposed method is evaluated on three public datasets. The experimental results demonstrate that the proposed method achieves a superior performance to that of state‐of‐the‐art methods.
Grating lobe suppression in focussed energy delivery for precision electronic warfare
Authors: Yang Zhong‐ping , Zhou Qing‐song , Li Zhi‐hui , Zhang Jian‐yun , Yang Shu‐ning
Published: July 2021

Focussed energy delivery (FED), which transmits energy to a specific area by ultrasparse arrays, is the core technique of precision electronic warfare (PREW). However, array sparsity results in severe grating lobes in practice, which greatly increase the risks of an interference system being attacked and unexpected jamming occurring in other devices. Here, two methods are presented which are aimed at suppressing grating lobes when implementing FED in the application of PREW to avoid the problems mentioned. Regarding the first method, a new metric based on the ‐norm is proposed to measure the maximum grating lobe and introduce the metric to the standard FED model. A multiobjective optimisation problem (MOP) is established and solved by the alternating direction penalty method (ADPM) framework. In the second method, the degrees of freedom of the transmitted signals are extended by equipping each platform with a group of linear uniform antennas. The corresponding MOP is established and block coordinate descent is employed to simplify the problem into two subproblems concerning the amplitude and phase components of the transmitted signals. Then, these two subproblems are solved using Taylor expansion and the ADPM framework. Simulation results are provided to demonstrate the advantages of the proposed methods over the state‐of‐the‐art methods.
Analysis of deformation characteristics of layered ground under uniform load
Authors: Xu Binbin
Published: July 2021

For the layered ground in a large area, the deformation under uniform load is analyzed numerically. Considering the work property of the concrete plane, the uneven settlement is strictly restrained using different foundation. In the process of settlement calculation, according to the linear interpolation of multiple borehole elevations, the geological profiles with different soil layer thickness are formed, and the influence of compressed soil layer thickness on the total settlement and uneven settlement is fully considered.
A new type of inorganic binder curing agent for soft soil
Authors: Zheng Airong
Published: July 2021

Aiming at the defects of traditional curing agent in strengthening soft clay, a new type of inorganic binder type soil curing agent has been developed. Compared with P.O 42.5 cement, the new soil stabilizer has smaller fineness and larger specific surface area. The strength of the soil solidified by the new curing agent is lower at the initial stage, but it increases rapidly after 24 hours. When the dosage is 10%, the 28-day strength of the soil solidified by the new curing agent is 2.1 times that of the soil solidified by cement. The soil solidified by the new curing agent can form more calcium hydroxide crystals and hydrated calcium silicate gel with more compact structure. After solidification, there are fewer fine particles in the soil.
The construction and application of the unit curtain wall system of the steel-aluminum combination
Authors: Tong Lu , Shuai Wang , Wenxiang Li , Le Luo , Shiqi Huang , Qinyou Fu , Wenhui Xiong
Published: July 2021

Curtain walls are widely used in the epidermis of buildings. At present, the unit curtain wall system production frame is mainly aluminum profile. But taking into account the weak aluminum strength and soft characteristics, the existing curtain wall often ensure the frame carrying capacity by increasing the amount of aluminum per unit area, which makes the high curtain wall costs. At the same time, the nodes of its production process are complex and require higher functions of production equipment. In this paper, a unit curtain wall system of steel-aluminum combination is proposed, which has the characteristics of simple construction, processing and installation, consisting of three key technologies including new steel-aluminum material combined with keel frame technology, glass curtain wall installation technology and cross-stitch node waterproofing technology. The system (1) in the construction, the integration of the concept of just soft. The unit structure of “steel column and aluminum profile” plays an advantage of high steel structure strength to ensure carrying capacity. In addition, the aluminum profile is fully plastic and the shape can be controlled. (2) In the production mode, the unit curtain wall is prefabricated by factory flow watering, and the processes are independent of each other, which is convenient for organizing processing equipment. (3) In the installation, the roof ring track and hoist are used to lift the unit plate, which avoids adverse shaking and rotation, reduces the risk of high-altitude operation and shortens the duration. This technology is of great reference significance to the construction of curtain wall of high rise buildings.
Application of HCSA expansive agent in crack control of mass concrete
Authors: Wang XinGang , Fan ShiGuang
Published: July 2021

The open section of the west artificial island of the Hong Kong-Zhuhai-Macao Bridge is a mass concrete structure. The concrete was poured in two times in the vertical direction, that is, the whole bottom plate was poured in the first time, and the middle wall and two side walls were poured in the second time. The side wall and middle wall are easy to crack due to the long time interval between two concrete castings. In order to study the function and effect of HCSA expansion agent in the crack control of mass concrete, the applicable condition of compensating shrinkage in the crack control of mass concrete is analyzed first. Then the effect of HCSA expansion agent was studied in laboratory and field. The experimental results show that HCSA expander has a good expansion effect under laboratory conditions, but it has no expansion effect on the middle side of the mass concrete test block in the engineering site, instead, it will further increase the internal temperature rise of concrete and increase the shrinkage strain of concrete. HCSA expander is helpless for crack control of mass concrete.
Engineering Approximate Analysis Method of Rod Projectile Penetrating Concrete Target
Authors: Feng Wang , Yaqiong Jiang , Yurong Ma , Dan Li , Wei Zhou
Published: July 2021

The penetration process of rod projectile into concrete target is very complex, and the theoretical analysis is very difficult. In this paper, by using the engineering approximation method, through some reasonable simplification of the rod projectile penetration model, the analytical formulas of the penetration resistance, penetration depth and other important physical quantities are established. Through the calculation of penetration depth, when the sliding friction coefficient is 0.1, the results are in good agreement with the experimental results. The results show that the higher the projectile density and the sharper the shape of the warhead, the stronger the penetration ability.
Study on Carbonation Index Prediction of Steel Fiber Concrete
Authors: Wu Duo
Published: July 2021

The addition of short steel wire, polypropylene, basalt and other fibers can improve the durability index of concrete, such as compression resistance, cracking resistance and carbonization resistance, which has been widely recognized in the industry. For the durability of fiber concrete, most of the current researches are qualitative, and the quantitative value of various index needs to be further investigated. In view of this, linear fitting and polynomial fitting were introduced into the prediction of durability index of fiber concrete in the present paper. The results show that the fitting method proposed is feasible and accurate for the carbonation index of fiber concrete.
Climate Responsive Design and Features Explore of Paul Rudolph’s Light Wood Residences
Authors: Jihui Xue , Shaopang Zhuang , Xinning Lan
Published: July 2021

In the middle of the 20th century, Paul Rudolph’s design practice of light wood residences in Sarasota area was well adapted to the local hot and humid subtropical climate. By tracing the origin of Paul Rudolph’s thought of climate responsive design, it’s possible to realize the design features of Paul Rudolph’s early works from heat protection and ventilation, and sum up the strategies and construction of his light wood residences for climate responsive design. Based on the characteristics of subtropical heat and humidity, Rudolph focused on innovations in building facades, roofs, and spaces, and proposed a series of climate-responsive design strategies and methods. Rudolph’s light wood practice has its own value in terms of technical principles, material technology, and regional characteristics, which are both rational and perceptual, and has enlightening value for the application of light buildings in subtropical areas and the design of contemporary light wood buildings.
Study on Seismic Behavior of Concrete-filled square steel tube column with core column-Steel Beam Joints
Authors: Meng Wang , Yi Tao
Published: July 2021

This paper has carried out the quasi-static tests of five specimens of FRP-UHPC column-steel beam joints with core columns, and the extensive parameter analysis of the joints by numerical simulation. The results show that the Concrete-filled square steel tube column with core column -Steel Beam Joints have strong bearing capacity. It has excellent deformability, stiffness and energy dissipation capacity, and works well under the condition of high axial compression ratio. The bearing capacity of the replacement beam specimen does not deteriorate significantly, which indicates that the Concrete-filled square steel tube column with core column -Steel Beam Joints is replaceable.
Internal force calculation of long span suspension bridge under vertical load based on elastic foundation beam algorithm
Authors: Yurong Ma , Qianwen Han , Feng Wang , Haixia Li
Published: July 2021

The calculation of suspension bridge under vertical load is the most important content of suspension bridge design calculation and the most important basis of main component design. Combined with the knowledge of structural mechanics, this paper puts forward the elastic foundation beam algorithm, and deduces the important formulas for the cross-section design and strength comparison of sling, cable and stiffening beam. In use, as long as the parameters are brought into the formula, it is more convenient and fast compared with the complex software modeling. The method proposed in this paper is used to check the strength of the completed Japanese Guanmen bridge, and the results are accurate enough. It is fast and reliable to use this method in the preliminary design and rapid safety assessment of suspension bridge.
Numerical Simulation of Foundation Treatment of Liquid Soil Materials
Authors: Yang Yong , Zhu BaoBing , Chen Juanjuan , Huang Chongwei , Feng Zhiyuan
Published: July 2021

As a new type of backfill material for abutment back treatment, there is still a gap in theoretical research and practical application. Aiming at the research on the treatment effect of the new backfill material liquid soil, this paper uses the finite element software for numerical simulation, comprehensively compares and analyzes the settlement and deformation characteristics of the new backfill material liquid soil and the conventional soil under the same working condition, and evaluates the treatment effect according to the calculation results; The results show that under the action of self weight load and traffic load, the overall settlement of both sides presents a similar distribution. In the horizontal direction, the settlement gradually increases from the near platform back to the far platform back. In the vertical direction, the settlement first increases and then decreases. Moreover, the road settlement under the action of vehicle load is larger than that under the action of self weight load only. However, the settlement of liquid soil backfill is far less than that of conventional soil backfill. Using liquid soil as backfill material can reduce the harm and economic loss caused by settlement to a certain extent.
Research on Construction Crack Diagnosis and Treatment Technology of Double-Column Large Cantilever Pre-Stressed Bent Cap
Authors: Wang Runjian
Published: July 2021

This paper took a pre-stressed bent cap of a high pier of a bridge as the research object, expounded the crack type and construction process of the bent cap, combined with the numerical calculation and analysis of the construction process to study the crack generation mechanism and its influence during the construction period of the bent cap. Besides, it gave the repair and treatment technology of jacking and unloading combined with pressure glue, so as to provide reference for the disease diagnosis and treatment of similar bridge structures.
Analysis and Research on Traditional Residential Architecture of Jiangxi
Authors: Wang Lin , Guo Juan
Published: July 2021

[Objective] Through in-depth study of traditional Gan residential buildings, it is found that in China’s traditional culture, nature is more important than architecture. Many people believe that architecture is like a man-made natural object, which can make people return to a feeling of living in nature, and is also a state of ideal life for many residents in China. [Methods] By using the analysis method, it is found that the traditional residential building structure of Ganpai is a bucket structure. The basic unit is the ‘enter’ relationship, which combines the ‘enter’ relationship, the adjustment of column spacing and the reduction of column to form the ‘+ -’ relationship. Through this way, a unique architectural group layout can be formed. [Conclusion] Therefore, we should fully combine traditional materials with modern information means to improve our traditional technology, so as to keep pace with the times, keep pace with the times and keep pace with the times.
Key Points of Inspection, Appraisal and Reinforcement Design for a Masonry Structure Reconstruction Project
Authors: Wei Zhang
Published: July 2021

In order to solve the problems in the reconstruction of masonry structure, this article combines the actual situation of a certain masonry structure building, analyzes its inspection and identification and reconstruction and reinforcement design, and proposes the key points of the reinforcement design, in order to provide references for relevant personnel to ensure the smooth implementation of the project and realize it the expected transformation goals.
A Simplified Uniaxial Stress-strain Curve of Concrete and Its Application in Numerical Simulation
Authors: Yafei Lou , Tao Zou , Jie Yang , Tao Jiang , Qingfang Zhang , Hexuan Hong
Published: July 2021

Detennining the constitutive model is a key procedure in numerical simulation of concrete structures. The uniaxial stress-strain curve is important information to determine the concrete constitutive model. This paper provided a simplified stress-strain curve of concrete that can be used in simulation. The comparison between Chinese Code and the simplified curve shows that the simplified curve of uniaxial compression is close to the code value. Numerical simulation of concrete beams show that the simplified curve proposed has high computational efficiency and good convergence.
Study on Dynamic Evaluation Method of Stability of Slope Controlled by Structural Plane Based on Deformation Characteristics
Authors: Luo Qun , Zhao Tianlong
Published: July 2021

The study on deformation characteristics of structural plane is the research foundation of structural plane mechanics and hydraulics. In this paper, a calculation method for dynamic evaluation of the stability of slope controlled by structural plane based on deformation characteristics was proposed on the basis of shear reinforcement three-fold line constitutive model, and it was applied to the example of Raytheon landslide in Chongqing-Guizhou high-speed railway. By comparison, the calculated results were in good agreement with the measured displacement results, and the displacement development process of the dangerous rock mass can be well simulated, thus verifying the feasibility and engineering practicality of the method.
Experimental Study on Nonlinear Characteristics of Permeability and Compressibility of Soft Clay
Authors: Yue Chang-xi , Chen Zhi-jun , Kou Xiao-qiang , Zhuang Dao-kun , Lu Jiang-xin
Published: July 2021

Consolidation and permeability tests were conducted on soft clays with different liquid limit by GDS consolidation apparatus. Some fitting parameters were studied for 4 common nonlinear permeability models based on the test data. But different soil samples have different parameters for the same model. In order to find the universal law of permeability coefficient and compressibility with the soil property and void ratio, the void ratio was normalized by the liquid void ratio eL, and the relationship of e/eL with logkv and logp were established based on the test data. The Chapman-Richard curve fitting model was adopted to best fit the obtained time-compression data. The relationship between e/eL with logkv was further verified using 30 groups of test data of permeability collected from China and abroad. The relationship between e/eL with logp was also discussed in this paper, and the fitted curves and nonlinear equations was further simplified into two linear equations at the point of e/eL=0.9 so as to consistent with the well-known theory. The nonlinear equations can be used to calculate the permeability and compressibility according to the void ratio and liquid limit.
The forecast and analysis of toll channel scale of expressway toll station
Authors: Pang Guanzheng
Published: July 2021

With the rapid growth of highway traffic, congestion of highway toll station has become a common phenomenon in peak hours. However, the congestion at the toll station has a serious impact on the normal operation of expressway. When the queuing vehicles overflow the toll station, the queue leader will lose control, and the operation of the main line vehicles will be seriously disturbed. This paper analyzes the causes of queuing phenomenon in toll stations, studies the characteristics of different toll channels and traffic flow, and then establishes the traffic flow theory model, and classifies the toll stations according to the average delay.
Research on Optimization of Sichuan Province National Territory Spatial Planning Based on Carbon Neutrality
Authors: Han Xuesong , Gao Huanggen , Zheng Yuan
Published: July 2021

The functional structure of territorial space is an important factor affecting the regional carbon cycle. The article explores the interaction mechanism between the functional structure of territorial space and carbon sources and carbon sinks, constructs a model for measuring and calculating territorial spatial carbon sources and carbon sinks, and investigates land changes in Sichuan Province, etc. Based on the data, the spatial carbon emission and absorption of Sichuan from 2010 to 2017 were calculated, and the carbon source carbon aggregate amount, structural composition and intensity change trend were analysed. The results show that changes in the spatial land use structure of Sichuan are closely related to carbon emissions, and the increase in construction land is the main reason for the substantial increase in carbon emissions. Finally, in combination with the vision and goals of "carbon neutrality", relevant optimization suggestions were put forward for the land and space planning of Sichuan Province.
Research on Automatic Train Driving Based on Fuzzy Proportion Integration Differentiation Iterative Control
Authors: Qi Zhengsheng , Liu Bohong , Wang Mengmeng
Published: July 2021

Automatic train driving system is an important subsystem of train operation control system, which can provide passengers with punctual, accurate, efficient and fast transportation services. At the same time, the accurate stop, comfort and stability of the train is an important index to measure the control performance of the train automatic driving system, and the accurate stop plays a vital role in the efficient operation of the train. Based on the characteristics of high-speed train parking, an accurate parking algorithm based on fuzzy PID iterative control was proposed to solve the problem of low parking accuracy caused by frequent switching of control output. On the basis of solving the differential equation of the train braking model, the gradient of the system is obtained, and then the learning parameters of the convergence condition are obtained to overcome the repeated uncertainty in the stopping stage. The simulation results show that the fuzzy PID iterative control for asymptotic stability is an effective method to realize the precise parking of trains, and has strong robustness against the train parameter uncertainties and external disturbances.
Optimization method of navigation information mode under the condition of multi-exit city expressway
Authors: Zhao HongJian
Published: July 2021

In recent years, mobile phone navigation software has been widely used, but the voice broadcast information of many navigation software is not clear, which is easy to cause confused driving. Urban expressway is an important artery of the city. The road and traffic conditions of urban expressways are extremely complicated, and there are many types of exits, which can easily cause confused driving. Therefore, optimization of navigation modes under the condition of multi-exit urban expressways is particularly important. Based on the experimental data of simulated driving, this paper focuses on the influence of voice navigation broadcast timing on driving under urban expressway, founding driver’s behavior is significantly different under diverse navigation modes. This paper uses the principal component analysis method to comprehensively evaluate the navigation broadcast timing, and gives the optimal navigation broadcast timings for various multi-exit urban expressways. In most cases, the first broadcast time should be 1500m from the exit. This paper clarifies the impact of navigation broadcast timing on driving, and optimizes the navigation mode of multi-exit urban expressways, which is of great significance for reducing yaw under navigation and improving navigation services.
Research on the Suitability Design of University Gate
Authors: Haixiu Liang , Ziyi Fan
Published: July 2021

With the development of university campus construction, the campus planning and architectural design concept also presents a variety of characteristics. The university gate is an important part of the university campus city interface, which is of great significance for the display of the overall image of the campus and the education concept. On the basis of summarizing the development process and morphological characteristics of university gate, this paper analyzes the suitability of its scale, culture and landscape, and puts forward corresponding design strategies. The paper concludes that the school gate scale suitability design should be based on people, from the perspective of human comfort, to determine the appropriate scale, cultural suitability design should take into account the discipline characteristics and regional culture, landscape suitability design should adapt to the climate characteristics.
Study on Planning and Design of Rainwater System Based on the Concept of Sponge City
Authors: Huang Hongli , Li Liangsong
Published: July 2021

In recent years, the concept of sponge city has been applied in different places. There are also many experts on sponge cities who believe that to build a sponge city in the city, we need to improve and optimize the rainwater system. In this way, we can better explore the way to plan and design the stormwater system when conducting the construction of the sponge city. This paper will also analyze and study the characteristics and functions of rainwater system planning in the construction of sponge city, and also point out the difficulties of the city in the construction of sponge city. Nowadays, the city must make clear its optimization direction, methods and principles in the transformation of rainwater system, and the optimization and transformation of rainwater system can also improve the construction progress of sponge city faster. The optimization and application of rainwater system can lay a solid foundation for the construction of sponge city.