bluuebunny/crossref_metadata_2025 huggingface dataset:
Validation of the Indonesian version of the graded chronic pain scale 2.0 in pain-related temporomandibular disorders
Authors: Tanti Ira , Wira Vivi Vidya Waty , Pragustine Yenni , Himawan Laura Susanti , Ariani Nina
Published: March 2020

BACKGROUND Pain associated with oral problems is one of the most frequent chronic pain of temporomandibular disorders (TMDs). This study was conducted to analyze the psychometric properties of the Indonesian version of the graded chronic pain scale 2.0 (GCPS-ID) in Indonesian patients with TMDs.

METHODS The English version of the GCPS version 2.0 was translated and back-translated according to international guidelines. This study conducted from June to December 2016 at the Dental Hospital, Faculty of Dentistry, Universitas Indonesia, and the participants were 202 TMDs patients who had never undergone temporomandibular joint surgery or suffered facial pain for more than 6 months. The evaluation of the GCPS-ID included the internal consistency test, test-retest reliability, and construct validity tests.

RESULTS The GCPS-ID had a high internal consistency (Cronbach’s alpha = 0.896). The intraclass correlation coefficient of the pain intensity and the disability score were 0.789 and 0.706, respectively. The convergent validity demonstrated a moderately positive correlation between the GCPS-ID and the Indonesian version of oral health impact profile for TMD for pain (r = 0.595; p<0.001) and disability (r = 0.488; p<0.001). The discriminant validity between GCPS-ID and the subjective patient’s quality of life revealed a weak positive correlation (r = 0.195; p = 0.191).

CONCLUSIONS GCPS-ID is a reliable and valid assessment tool for evaluating TMD pain in Indonesia.
Terahertz three-dimensional monitoring of nanoparticle-assisted laser tissue soldering
Authors: Dong Junliang , Breitenborn Holger , Piccoli Riccardo , Besteiro Lucas V. , You Pei , Caraffini Diego , Wang Zhiming M. , Govorov Alexander O. , Naccache Rafik , Vetrone Fiorenzo , Razzari Luca , Morandotti Roberto
Published: March 2020

In view of minimally-invasive clinical interventions, laser tissue soldering assisted by plasmonic nanoparticles is emerging as an appealing concept in surgical medicine, holding the promise of surgeries without sutures. Rigorous monitoring of the plasmonically-heated solder and the underlying tissue is crucial for optimizing the soldering bonding strength and minimizing the photothermal damage. To this end, we propose a non-invasive, non-contact, and non-ionizing modality for monitoring nanoparticle-assisted laser-tissue interaction and visualizing the localized photothermal damage, by taking advantage of the unique sensitivity of terahertz radiation to the hydration level of biological tissue. We demonstrate that terahertz radiation can be employed as a versatile tool to reveal the thermally-affected evolution in tissue, and to quantitatively characterize the photothermal damage induced by nanoparticle-assisted laser tissue soldering in three dimensions. Our approach can be easily extended and applied across a broad range of clinical applications involving laser-tissue interaction, such as laser ablation and photothermal therapies.
Simple method to extract extinction coefficients of films with the resolution of 10−5 using just transmission data and application to intermolecular charge-transfer absorption in an exciplex-forming organic film
Authors: Kim Hwang-Beom , Kim Jang-Joo
Published: March 2020

A simple method is presented to determine the thickness, refractive index and extinction coefficient of a film with the resolutions of ±1 nm, ±2 × 10−3, and 6 × 10−5, respectively. The method requires only ultraviolet-visible-near-infrared spectroscopy measurement of the transmittance of films with thicknesses of a few micrometers. A very small extinction coefficient of intermolecular charge transfer (CT) absorption of an exciplex-forming organic film is measured in the sub-bandgap wavelength region. This is to demonstrate that the CT absorption with extinction coefficient in the range of 10−3 to 10−5 can be measured indeed using the method, which is in the same resolution as photothermal deflection spectroscopy and Fourier transform photocurrent spectroscopy. The simplicity and feasibility of the proposed approach is expected to promote active study of intermolecular CT absorption in exciplex-forming films.
Laser feedback interferometry in multi-mode terahertz quantum cascade lasers
Authors: Qi Xiaoqiong , Agnew Gary , Taimre Thomas , Han She , Lim Yah Leng , Bertling Karl , Demić Aleksandar , Dean Paul , Indjin Dragan , Rakić Aleksandar D.
Published: March 2020

The typical modal characteristics arising during laser feedback interferometry (LFI) in multi-mode terahertz (THz) quantum cascade lasers (QCLs) are investigated in this work. To this end, a set of multi-mode reduced rate equations with gain saturation for a general Fabry-Pérot multi-mode THz QCL under optical feedback is developed. Depending on gain bandwidth of the laser and optical feedback level, three different operating regimes are identified, namely a single-mode regime, a multi-mode regime, and a tuneable-mode regime. When the laser operates in the single-mode and multi-mode regimes, the self-mixing signal amplitude (peak to peak value of the self-mixing fringes) is proportional to the feedback coupling rate at each mode frequency. However, this rule no longer holds when the laser enters into the tuneable-mode regime, in which the feedback level becomes sufficiently strong (the boundary value of the feedback level depends on the gain bandwidth). The mapping of the identified feedback regimes of the multi-mode THz QCL in the space of the gain bandwidth and feedback level is investigated. In addition, the dependence of the aforementioned mapping of these three regimes on the linewidth enhancement factor of the laser is also explored, which provides a systematic picture of the potential of LFI in multi-mode THz QCLs for spectroscopic sensing applications.
55  W  kilohertz-linewidth core- and in-band-pumped linearly polarized single-frequency fiber laser at 1950  nm
Authors: Guan Xianchao , Yang Changsheng , Gu Quan , Wang Weiwei , Tan Tianyi , Zhao Qilai , Lin Wei , Wei Xiaoming , Yang Zhongmin , Xu Shanhui
Published: March 2020

Based on core- and in-band-pumped polarization-maintaining

T
m

3
+

-doped single-cladding fiber (PM-TSF, the core diameter is 9 µm) by a 1610 nm fiber laser and a distributed Bragg reflector seed laser, a linearly polarized single-frequency fiber laser (LP-SFFL) at 1950 nm with an output power of 55.3 W and a laser linewidth of 6.95 kHz is demonstrated. The output beam qualities of

M

x
2

and

M

y
2

are measured to be 1.01 and 1.03, respectively. The slope efficiency with respect to the launched pump power is 71.0%, in comparison with a theoretical quantum efficiency of 82.6%. A polarization-extinction ratio of 19 dB and an optical signal-to-noise ratio of 58 dB are obtained from the 1950 nm LP-SFFL. To the best of our knowledge, to date, this is the highest power of 2.0 µm SFFL output directly from a strict single-mode active fiber. Our experiment offers a promising solution to the current limitations of the high-performance fiber lasers at 2.0 µm, which is particularly essential for coherent detection.
Urbach-edge-assisted electro-absorption for enhanced free-space optical modulation
Authors: Hristovski I. R. , Lesack N. I. , Herman L. A. , Holzman J. F.
Published: March 2020

In this work, we introduce an electro-absorption (EA)-based retro-modulator for effective realization of free-space optical communications via passive downlinks. Demands for deep modulation and broad directionality in such links are met by its corner-cube assembly of EA-modulators. The EA-modulators use semi-insulating InP as its band edge absorption exhibits an Urbach tail near the 980-nm wavelength of the laser light. This enables Urbach-edge-assisted EA, which allows the field-induced absorption to be optimized via temperature. The theory, from a uniting of the Einstein model and Franz–Keldysh effect, and experiments, from a prototype, show good agreement with deep (greater than 15%) modulation depths. Such functionality can meet the key demands of emerging free-space optical communication links.
Hidden linear optical response reveals crystalline symmetry
Authors: Zhu X. D. , Zhang Hang
Published: March 2020

We show that a linear quadrupole response from a crystalline material to externally applied optical fields exists and has gone unnoticed, even though its nonlinear optical cousin has been studied and explored extensively for decades. Such a linear quadrupole response reveals the symmetry of the crystal, just as its nonlinear optical counterpart has done, and can be used to investigate phase transitions non-intrusively with high spatial and temporal resolution.
Correlation signatures for a coherent three-photon scattering in waveguide quantum electrodynamics
Authors: Chen Zihao , Zhou Yao , Shen Jung-Tsung
Published: March 2020

We study the correlation signatures of a coherent three-photon scattering process by computationally investigating scattering photon wavefunctions, correlation functions, and nonlinear conditional phases. It is shown that both the three-photon bound states and the hybrid states, which consist of two-photon bound states and one unbound photon, contribute to all the correlation signatures. All computational correlation signatures are in good agreement with a recent experiment, wherein a weak coherent photonic state propagates through a quantum nonlinear Rydberg medium [Liang et al., Science 359, 783 (2018)SCIEAS0036-807510.1126/science.aao7293].
As falsificações e o bem-estar
Authors: Pimenta Carlos
Published: March 2020

As “falsificações” e as “fraudes” são, muitas vezes, irmãs gémeas. Este artigo analisa alguns aspectos da fraude. Caracteriza-se pelo logro, dimensão social e negação da ética ou da lei. Redutora do bem-estar, exige-se combatê-la. Alerta para alguns conceitos operacionais. Refere a relevância da dimensão cultural.
Migrating merchants. Trade, nation, and religion in seventeenth-century Hamburg and Portugal
Authors: Gouveia Jaime Ricardo
Published: March 2020

https://doi.org/10.14195/0870-4112_3-5_13
Eruditos, falsificações e miliários
Authors: Mantas Vasco Gil
Published: March 2020

A falsificação de testemunhos epigráficos foi praticada vulgarmente por numerosos humanistas, destacando-se em Portugal as invenções de André de Resende e de frei Bernardo de Brito. Rudemente criticados pelos epigrafistas e historiadores do século XIX, como Emil Hübner, inspiraram críticas que levaram a suspeitar sistematicamente das informações destes autores, longamente copiados por muitos outros. Todavia, uma releitura sem preconceitos permite considerar como autênticos grande parte dos miliários que publicaram.
Falsificação e artes: chuvas oblíquas
Authors: Júdice Nuno , Anacleto Marta Teixeira
Published: March 2020

https://doi.org/10.14195/0870-4112_3-5_12
Os finais da Odisseia: a autenticidade do canto XXIV
Authors: Loureiro João Diogo R. P. G.
Published: March 2020

Os finais da Odisseia: a autenticidade do canto XXIV
A Antiguidade no cinema: Caligula de Tinto Brass e Bob Guccione (1979)
Authors: Rodrigues Nuno Simões
Published: March 2020

Apresentado em 1979, o Caligula de T. Brass e B. Guccione marcou uma época pela forma como a Antiguidade passou a representar uma ideia de «pornotopia», i.e., um tempo em que a sexualidade, alegadamente, teria um valor e um significado bem distintos dos do século XX. Por outro lado, recuperando reflexões já ensaiadas por um autor como Camus, Calígula ressurge nesta leitura metatextual como a imagem de um poder arbitrário e demente, reforçando ideias já germinadas nos autores antigos. Assim se justifica também que uma produção desta natureza reúna actores da chamada «Escola shakespeareana» com nomes que provinham da indústria pornográfica.
Empreendedorismo Cultural e Economia Criativa: A Companhia de Teatro “Grupo Galpão”
Authors: Reis Janaína Martins dos , Zille Luciano Pereira
Published: March 2020

Objetivo: Analisar e descrever o empreendedorismo cultural no contexto da economia criativa, na percepção do Grupo Galpão, sediado na cidade de Belo Horizonte-MG.Metodologia: Pesquisa descritiva, de abordagem qualitativa por meio de estudo de caso. A unidade de análise foi o empreendedorismo cultural e a unidade de observação o Grupo de Teatro Galpão. A coleta dos dados foi por meio de entrevista semiestruturada e a análise pela técnica de análise de conteúdo categorial.Resultados: O grupo revelou amplo conhecimento sobre o tema, cujos principais desafios são a dificuldade de planejamento dos eventos em médio e longo prazos e a dificuldade de gerar receita exclusivamente pelo público participante. Identificou-se que a criação e manutenção do Centro Cultural tem contribuído com vários projetos de acesso à cultura de interesse da sociedade, nos quais a Lei Rouanet vem tendo papel relevante.Contribuições teóricas: Ampliação do conhecimento dos estudos relacionados ao empreendedorismo cultural, enfatizando a economia criativa, cujas pesquisas estão caminhando no sentido de alcançarem solidez do ponto de vista científico.Relevância/originalidade: Contempla principalmente os contextos acadêmico e social, no sentido de ampliar os estudos direcionados ao empreendedorismo cultural. A sua originalidade está centrada na pesquisa de uma companhia de teatro de destaque no Brasil, focando o empreendedorismo cultural na dimensão da economia criativa. Contribuições sociais/gestão: Fomenta o desenvolvimento de uma sociedade mais igualitária em relação ao espírito empreendedor, por meio da disseminação cultural, com foco nos princípios da economia criativa e da gestão empreendedora.
FCS Teacher Transformation: A Shift in Poverty Perceptions
Authors: Arnett-Hartwick Sally E. , Harpel Tammy
Published: March 2020

The purpose of this research was to evaluate the impact of a poverty simulation on family and consumer sciences (FCS) teachers' perception of poverty. FCS teachers (N = 47) from a midwestern state participated in a poverty simulation. Participants completed a questionnaire prior
to and following participation in the simulation. Quantitative data suggested improvements in attitude, and the qualitative data produced themes for future education activities and teacher-student interactions. The simulation encourages more positive attitudes among FCS teachers regarding
their perception of poverty.
Technology in Education: Learning Opportunities for Teachers and Students
Authors: Reddy Shweta L. , Bubonia Janace
Published: March 2020

The purpose of using technology in education today is to provide students with an opportunity to learn a given topic at their own pace and convenience. Integrating technology into education is of considerable value because using technology effectively has the potential to make learning
meaningful (Kirschner, 2015). Within a decade, technology has transformed education by affecting (a) the method of delivering course content to students, (b) student engagement with course content outside class hours, (c) the capability of a teacher to create different learning opportunities
for students of diverse learning styles, (d) and the ability to convert course information into knowledge bytes for students of varied educational backgrounds and abilities. In this short span of time, the purpose of using technology in education has shifted from merely delivering course content
to aiding students in learning the content. Using technology in education is more like "the idea that you can learn something without directly learning it" (Henriksen et al., 2019, p. 86). In other words, even though technological competence may not be the objective of a course, learning the
technology will certainly help in achieving the objective of the course.
Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation
Authors: Reed Craig C. , Corder S. Ryanne , Kim Erin , Sanders Emily , Tappata Manaswita , Eluri Swathi , Dellon Evan S.
Published: March 2020

OBJECTIVES:

The prevalence of psychiatric disease in patients with eosinophilic esophagitis (EoE) is not fully characterized. We aimed to determine the prevalence of psychiatric disease and centrally acting medication use in a cohort of children and adults with EoE and evaluated whether psychiatric disease affects the EoE clinical presentation.

METHODS:

We conducted a retrospective study of newly diagnosed cases with EoE at the University of North Carolina from 2002 to 2018. Psychiatric comorbidities and relevant treatments were extracted from the medical records. The demographic and clinical features of patients with EoE with and without psychiatric diagnoses, and those with and without psychiatric medication use, were compared.

RESULTS:

Of 883 patients (mean age 26.6 years, 68% men, 79% white), 241 (28%) had a psychiatric comorbidity. The most common diagnosis was anxiety (23%) followed by depression (17%); 28% of patients were treated pharmacologically. There were 45 patients (5%) treated pharmacologically without a psychiatric diagnosis for chronic pain syndromes, insomnia, and/or epilepsy. Cases with EoE with a psychiatric diagnosis were more likely to be women, white, and 18 years or older and to have a longer symptom duration before diagnosis.

DICUSSION:

Psychiatric comorbidities were common in EoE, seen in a third of adults and more than 1 in 7 children, and with similar proportions receiving a prescription medication. These illnesses affected the EoE presentation because psychiatric comorbidities were more likely in older, female, and white patients with a longer duration of symptoms preceding diagnosis.
What is Effective Research Communication? Towards Cooperative Inquiry with Nunavut Communities
Authors: Henri Dominique A. , Brunet Nicolas D. , Dort Hillary E. , Hambly Odame Helen , Shirley Jamal , Gilchrist H. Grant
Published: March 2020

Communication is recognized as the foundation of developing partnerships in science. In this study, we assess the effectiveness of several communication processes, practices, and tools used by wildlife researchers in northern communities in Arctic Canada. A case study was conducted in the communities of Cape Dorset and Coral Harbour (Salliq), Nunavut, Canada, to assess the effectiveness of research communication approaches carried out by the northern marine bird research group of Environment and Climate Change Canada, which has a long-standing research relationship with these two communities. Our objectives were to 1) explore local experiences with research—marine bird research in particular, 2) examine what communication approaches and tools Nunavummiut viewed as most effective for learning about research activities and feeling engaged in the process, and 3) identify new and emerging communication needs in Nunavut communities to support more effective research partnerships. Our findings indicate that several communication methods used by wildlife researchers, such as community meetings, have become less effective because of changing information-sharing practices at the community level. Other communication practices, such as using social media, hold much promise, but as of yet are underutilized by researchers, though of interest to northern communities. Acknowledging that every northern community is unique, with context-specific priorities, capacities, and needs, effective research partnerships should be built upon communication approaches that foster cooperative inquiry and learning. In progress towards this goal, we explore two emerging and related themes: first, access to information and communication technologies in the two communities, and second, the engagement of youth in Arctic research communication and delivery.
Измерение субъективного благополучия детей в России: от локальных социальных практик до федеральной стратегии
Authors: Арчакова Татьяна Олеговна , Гарифулина Эльвира Шамильевна
Published: March 2020

В статье рассматриваются подходы к определению и операционализации понятия «субъективное благополучие детей» в российской практике. Анализируются эмпирические данные об использовании показателей благополучия детей в работе 69 государственных и некоммерческих организаций, реализующих практики в сфере социального сиротства и поддержанных Фондом Тимченко в 2016—2018 гг. Приводятся примеры инструментов, разработанных в рамках прикладных социальных проектов для оценки субъективного благополучия детей, в том числе не имеющих возможности для вербального выражения своего мнения. Обсуждаются факторы, осложняющие от измерения субъективного благополучия детей на уровне отдельных социальных практик/проектов и организаций к большему масштабу. На основе анализа даны рекомендации по проектированию собственных российских или адаптации зарубежных индексов детского благополучия более высокого уровня (региональных, федеральных).
AJET Bibliometrics
Authors: Heinrich Eva , Henderson Michael , Redmond Petrea
Published: March 2020

The bibliometric data in this editorial provide readers with information about the journal’s publication, review and article access statistics, the articles attracting the most interest over the past year and the citation performance of the journal.
The group of self-homotopy equivalences ofAn2-polyhedra
Authors: Costoya Cristina , Méndez David , Viruel Antonio
Published: March 2020

LetXbe a finite typeAn2{A_{n}^{2}}-polyhedron,n≥2{n\geq 2}. In this paper, we study the quotient groupℰ⁢(X)/ℰ*⁢(X){\mathcal{E}(X)/\mathcal{E}_{*}(X)}, whereℰ⁢(X){\mathcal{E}(X)}is the group of self-homotopy equivalences ofXandℰ*⁢(X){\mathcal{E}_{*}(X)}the subgroup of self-homotopy equivalences inducing the identity on the homology groups ofX. We show that not every group can be realised asℰ⁢(X){\mathcal{E}(X)}orℰ⁢(X)/ℰ*⁢(X){\mathcal{E}(X)/\mathcal{E}_{*}(X)}forXanAn2{A_{n}^{2}}-polyhedron,n≥3{n\geq 3}, and specific results are obtained forn=2{n=2}.
Effect of ionic liquid on the extraction of uranium with pillar[5]arene-based phosphine oxide from nitric acid solutions
Authors: Gan Quan , Cai Yimin , Fu Kuirong , Yuan Lihua , Feng Wen
Published: March 2020

The extraction of U(VI) from aqueous nitric acid solutions with pillar[5]arene-based phosphine oxide (L) and [C8mim][NTf2] ionic liquid dissolved in 1,2-dichloroethane was explored. A great positive impact in this system was observed. The effect of IL concentration in the organic phase and HNO3 concentration in the aqueous phase is considered. The distribution ratios of U(VI) were significantly enhanced upon adding a small amount of ionic liquid as compared with organic diluent. The extraction system was also examined for its ability towards extraction of lanthanides and Th4+. The results revealed higher separation factors towards UO2
2+ over Th4+ in the presence of ionic liquid compared with organic diluent. Other factors such as C8mim+ and NTf2
− have also been considered. This extraction system has shorter equilibrium time as compared with in IL diluent. Stripping experiments showed almost quantitative back extraction of UO2
2+ within two stages. With high selectivity towards UO2
2+ and efficient back extraction, this new POP5A-ionic liquid-organic diluent system shows promise for future application of uranium recovery.
La nature du sens : Neuroception, perception ou sémioception ?
Authors: Beividas Waldir
Published: March 2020

La théorie sémiotique s’est développée comme une théorie de la production du sens et de sa manifestation dans les diverses pratiques humaines. Dernièrement, elle est demandée à rendre compte de l’émergence du sens, de sa nature. Pour la philosophie merleaupontienne ce point d’origine est donné dans la perception, comme le premier sol où le sens se fait. La perception détient la primauté de la construction du monde signifiant pour l’homme. Dans les sciences naturelles, les neurosciences pointent vers le cerveau, en particulier l’équipement neuronal que nous avons en tant qu’hommes, comme le siège de la construction du sens. Notre connaissance du monde vient d’une « neuroception », un néologisme inévitable pour lui donner un air de famille avec celui de la « per-ception ». Devant ces deux positions théoriques, nous pouvons en sémiologie et linguistique offrir et défendre l’hypothèse que notre connaissance du monde est péremptoirement générée dans les mailles des langages. Une opération de sémioception, basée sur l’acte sémiologique arbitraire des langages, commande la perception humaine elle-même, avec antécédence. Ce n’est pas le cerveau qui « fait de l’esprit », c’est plutôt le langage qui « fait le cerveau » humain.
Le rôle complexe de la figurativité dans la sémiotique greimassienne
Authors: Harkot-de-La-Taille Elizabeth
Published: March 2020

La figure, dans la sémiotique greimassienne, héritant d’une élaboration polysémique chez Hjelmslev, appartient tant au plan de l’expression qu’au plan du contenu. Sur le plan du contenu, elle s’introduit au niveau discursif et renvoie à un thème, qu’elleconcrétise. Par ailleurs, dans Sémantique Structurale, les traces d’information que nos cinq sens nous apportent sont aussi appelées figures, et c’est par leur intermédiaire que le monde naturel joue un rôle dans la naissance du sens. Ces figures engendrées par la perception sont des figures d’expression et appartiennent de ce fait au plan de l’expression. L’unification des deux types de figures en une figurativité générique, située au niveau discursif et subdivisée en figurativitéstricto sensu, dite de surface, et figurativitélato sensu, dite profonde (Landowski. 2017.Com Greimas : interações semióticas. São Paulo : Editora CPS e Estação das Letras e Cores) est discutée avec l’apport d’auteurs de la sémiotique française et la structure quadratique du signe due au Groupe µ (2015.Principia semiotica : aux sources du sens. Bruxelles : Les Impressions Nouvelles : 283–292). Cette discussion nous suggère la figurativité comme transversale au parcours génératif du sens et contribuant à l’opération de conversion, dans la mesure où des traces du monde naturel refont surface sous la forme de figures du monde, sur le plan du contenu discursif.
Bidirectional Gated Recurrent Deep Learning Neural Networks for Smart Acoustic Emission Sensing of Natural Fiber–Reinforced Polymer Composite Machining Process
Authors: Wang Zimo , Dixit Pawan , Chegdani Faissal , Takabi Behrouz , Tai Bruce L. , El Mansori Mohamed , Bukkapatnam Satish
Published: March 2020

Natural fiber–reinforced polymer (NFRP) composites are increasingly considered in the industry for creating environmentally benign product alternatives. The complex structure of the fibers and their random distribution within the matrix basis impede the machinability of NFRP composites as well as the resulting product quality. This article investigates a smart process monitoring approach that employs acoustic emission (AE)—elastic waves sourced from various plastic deformation and fracture mechanisms—to characterize the variations in the NFRP machining process. The state-of-the-art analytic tools are incapable of handling the transient dynamic patterns with long-term correlations and bursts in AE and how process conditions and the underlying material removal mechanisms affect these patterns. To address this gap, we investigated two types of the bidirectional gated recurrent deep learning neural network (BD-GRNN) models, viz., bidirectional long short-term memory and bidirectional gated recurrent unit to predict the process conditions based on dynamic AE patterns. The models are tested on the AE signals gathered from orthogonal cutting experiments on NFRP samples performed at six different cutting speeds and three fiber orientations. The results from the experimental study suggest that BD-GRNNs can correctly predict (around 87 % accuracy) the cutting conditions based on the extracted temporal-spectral features of AE signals.
Excessive reassurance seeking mediates relations between rumination and problematic smartphone use
Authors: Elhai Jon D. , Rozgonjuk Dmitri , Alghraibeh Ahmad M. , Levine Jason C. , Alafnan Ali A. , Aldraiweesh Ahmed A. , Aljomaa Suliman S. , Hall Brian J.
Published: March 2020

Aside from depression and anxiety, less is known about the relationship of problematic smartphone use (PSU) to other psychopathology- related variables. The authors' aim was to test previously neglected variables in relation to PSU: rumination and excessive reassurance seeking behavior (ERSB). The authors recruited 295 college students for a web-based survey of smartphone use frequency, PSU, depression and anxiety, ruminative thinking, and ERSB. The authors tested linear regression and mediation models, assessing rumination and ERSB as mediating associations between depression/anxiety severity with PSU, adjusting for age, sex, and smartphone use frequency. Results demonstrate that ERSB was significantly related to PSU severity, and ERSB mediated the association between rumination and PSU. Furthermore, the combination of rumination and ERSB mediated relations between both depression and anxiety severity with PSU. Results provide evidence for ERSB as an important variable in understanding relationships between psychopathology symptoms and PSU severity among college students.
Synaptic Specificity and Application of Anterograde Transsynaptic AAV for Probing Neural Circuitry
Authors: Zingg Brian , Peng Bo , Huang Junxiang , Tao Huizhong W. , Zhang Li I.
Published: March 2020

Revealing the organization and function of neural circuits is greatly facilitated by viral tools that spread transsynaptically. Adeno-associated virus (AAV) exhibits anterograde transneuronal transport, however, the synaptic specificity of this spread and its broad application within a diverse set of circuits remains to be explored. Here, using anatomic, functional, and molecular approaches, we provide evidence for the preferential transport of AAV1 to postsynaptically connected neurons and reveal its spread is strongly dependent on synaptic transmitter release. In addition to glutamatergic pathways, AAV1 also spreads through GABAergic synapses to both excitatory and inhibitory cell types. We observed little or no transport, however, through neuromodulatory projections (e.g., serotonergic, cholinergic, and noradrenergic). In addition, we found that AAV1 can be transported through long-distance descending projections from various brain regions to effectively transduce spinal cord neurons. Combined with newly designed intersectional and sparse labeling strategies, AAV1 can be applied within a wide variety of pathways to categorize neurons according to their input sources, morphology, and molecular identities. These properties make AAV1 a promising anterograde transsynaptic tool for establishing a comprehensive cell-atlas of the brain, although its capacity for retrograde transport currently limits its use to unidirectional circuits.

SIGNIFICANCE STATEMENTThe discovery of anterograde transneuronal spread of AAV1 generates great promise for its application as a unique tool for manipulating input-defined cell populations and mapping their outputs. However, several outstanding questions remain for anterograde transsynaptic approaches in the field: (1) whether AAV1 spreads exclusively or specifically to synaptically connected neurons, and (2) how broad its application could be in various types of neural circuits in the brain. This study provides several lines of evidence in terms of anatomy, functional innervation, and underlying mechanisms, to strongly support that AAV1 anterograde transneuronal spread is highly synapse specific. In addition, several potentially important applications of transsynaptic AAV1 in probing neural circuits are described.
Using the FRAMER Scaffold Design Framework to Support Students in Learning & Understanding Biology
Authors: Sabel Jaime L.
Published: March 2020

Students need support to learn the core ideas, practices, and crosscutting concepts that make up the field of biology so that they can both be successful as biologists and make informed decisions that require biological understanding. One way instructors can support students in these endeavors is to provide students with specific scaffolds the instructors design to structure students' performance on a task or engagement in a behavior. With the focus on both scientific concepts and practices, instructors may also need support to be able to develop scaffolds that align with suggested best practices. I offer a framework, referred to as FRAMER, and suggestions for instructors interested in developing scaffolds for biology courses, and provide an example of a successful scaffold implementation in an undergraduate biology course.
Kebijakan Pre-Merger Notification Badan Usaha Sebagai Penegakan Hukum di Era Revolusi Industri 4.0
Authors: Ibrahim Suhandi Farid
Published: March 2020

Konsekuensi dari adanya dinamika globalisasi menimbulkan suatu fenomena apriori yang dinamakan dengan revolusi industri 4.0 sehingga hal ini mejadi tantangan bagi Komisi Pengawasan Persaingan Usaha (KPPU) untuk dapat melindungi keadaan pasar yang berkembang sedinamika mungkin. Melalui hal tersebut maka kewenangan daripada KPPU perlu untuk dioptimalisasikan demi menyesuaikan dinamika pasar. Pelaksanaan merger suatu perusahaan menjadi keadaan yang berpotensi menimbulkan suatu bentuk persaingan usaha yang tidak sehat. Hal ini tentu mejadi kewenangan KPPU untuk dapat memberikan pengawasan dan penilaian akan hal tersebut, namun dengan masih berlakunya rezim pasca- notifikasi merger membuat terjadinya kemungkinan adanya pembatalan suatu merger yang berdampak pada kerugian yang diderita perusahaaan. Oleh karena itu diperlukan perubahan rezim menjadi pra-notifikasi merger yang telah melalui beberapa pertimbangan yang diperlukan. Dengan demikian, maka diharapkan KPPU mampu menjadi pelindung utama akan terciptanya keadaan pasar yang adil dan kondusif.
Isu Pekerja Anak Dan Hubungan Dengan Hak Asasi Manusia
Authors: Faridah Siti , Afiyani Laila
Published: March 2020

Terdiri Seiring waktu, eksploitasi pekerja anak di Indonesia meningkat setiap tahun. Hal ini disebabkan rendah ekonomi dan pendidikan yang kekuatan anak-anak untuk bekerja dan membantu orang tua mereka secara finansial. Yuridis, Indonesia memiliki peraturan yang mengatur pekerja anak yang tercantum dalam undang-undang ketenagakerjaan. Hal ini dimaksudkan agar hak-hak anak-anak tidak diabaikan tapi masih dilindungi oleh pemerintah. Namun, aturan yang ada dari waktu ke waktu tidak sesuai dengan kompleksitas masyarakat yang terus berkembang sampai sekarang. Sehingga seolah-olah aturan yang berlaku tidak memiliki kekuatan untuk mengatur tatanan masyarakat. Menurut Konvensi Hak Anak, anak-anak memiliki hak untuk dilindungi dari segala bentuk eksploitasi ekonomi dan dari segala bentuk pekerjaan berbahaya dan mengganggu pendidikan, kesehatan, fisik, mental, spiritual, aspek moral dan sosial anak. Dalam hal ini, ada tiga pendekatan untuk melihat masalah pekerja anak, yaitu penghapusan, perlindungan, dan pemberdayaan.
HOXA10 co-factor MEIS1 is required for the decidualization in human endometrial stromal cell
Authors: Xu Yawen , Lu Jinhua , Wu Jinxiang , Jiang Ruiwei , Guo Chuanhui , Tang Yedong , Wang Haibin , Kong Shuangbo , Wang Suqing
Published: March 2020

Decidualization is a critical process for embryo implantation and pregnancy maintenance in humans. The homeobox gene HOXA10 has been widely studied in endometrial receptivity establishment and decidualization. MEIS1, a three-amino-acid loop extension (TALE) family homeobox gene, has been proven to be a co-factor for HOXA10 in mouse uterus. However, the interaction between MEIS1 and HOXA10 in the human decidual cells remains to be elucidated. siRNA and CRISPR-Cas9 were employed to knockdown and knockout MEIS1 in the cultured human endometrial stromal cells, and it was found that MEIS1 deficiency leads to impaired decidualization. The physical interaction between the MEIS1 and HOXA10 in human endometrial stromal cell was confirmed by immunoprecipitation. Moreover, KAT2B and ETA were proved to be downregulated in the absence of MEIS1, and luciferase reporter and ChIP assays demonstrated that MEIS1-HOXA10 complex binds to the promoters of KAT2B and ETA and regulates their activity. Overexpression of KAT2B and ETA can partially rescue the decidualization defects in MEIS1-knockout HESCs. Taken together, these data suggest that MEIS1 plays an indispensable role in decidualization in human endometrial stromal cells, and MEIS1 interacts with HOXA10 to regulate the downstream genes, such as KAT2B and ETA. These findings will contribute to our understanding about the regulatory network in the process of decidualization in humans.
Immune cell trafficking across the blood-brain barrier in the absence and presence of neuroinflammation
Authors: Marchetti Luca , Engelhardt Britta
Published: March 2020

To maintain the homeostatic environment required for proper function of CNS neurons the endothelial cells of CNS microvessels tightly regulate the movement of ions and molecules between the blood and the CNS. The unique properties of these blood vascular endothelial cells are termed blood-brain barrier (BBB) and extend to regulating immune cell trafficking into the immune privileged CNS during health and disease. In general, extravasation of circulating immune cells is a multi-step process regulated by the sequential interaction of adhesion and signalling molecules between the endothelial cells and the immune cells. Accounting for the unique barrier properties of CNS microvessels, immune cell migration across the BBB is distinct and characterized by several adaptations. Here we describe the mechanisms that regulate immune cell trafficking across the BBB during immune surveillance and neuroinflammation, with a focus on the current state-of-the-art in vitro and in vivo imaging observations.
Constructing Criminological Knowledge: the Experience of the Development and Implementation of Interdisciplinary Criminology Studies at Vilnius University
Authors: Dobryninas Aleksandras , Aleknevičienė Jolanta , Pocienė Aušra
Published: March 2020

Taking a social constructionists perspective, the article presents not widely known sides in the development of modern Lithuanian criminology related to the emergence, formation and development of criminological studies at Vilnius University. Since the emergence of the first criminological courses in Lithuanian academic institutions, they, as in other European continent universities, were usually taught in law faculties and schools. However, in the mid of 1990s, a unique situation occurred at Vilnius University, where sociologists and psychologists started teaching criminological courses at the Faculty of Philosophy. Later, in 1999, with the methodical help of the Faculty of Law, the teaching staff of the Faculty of Philosophy developed and implemented two-year masters programs in sociological and psychological criminology.The gained educational experience in managing and implementing interdisciplinary criminology programs at Vilnius University paved the way for introducing in 2017 new interdisciplinary bachelor study programme in criminology. On the one hand, the emergence of such studies would be impossible without long-term close and constructive collaboration between the sociologists, psychologists and lawyers of Vilnius University and, on the other, - without the active involvement of the new generation of young criminologists in the educational process. Authors emphasise, that the emergence and development of the criminology studies in Lithuania was influenced by both the developmental context of criminology at European and North American universities and the methodological and organisational support, which Lithuanian criminologists had been receiving from their colleagues from western academic institutions.Authors also present and describe the developmental process of both master and bachelor studies: they introduce the leaders, organisers and lecturers of these programs, observe their structure and inner consistency, analyse the role of interdisciplinarity in organising criminology studies. The article identifies the challenges and problems facing both the teaching and learning processes and their potential solutions, which should ensure the quality of studies, their correspondence to the state-of-art methods in criminological research and practical needs of contemporary society.
Gender-based Violence in Lithuania during Late-Soviet Period and Post-Soviet Transformation
Authors: Kareniauskaitė Monika
Published: March 2020

The aim of this article is to research the concept and different definitions of gender-based violence in Lithuanian society during the late Soviet period and the first decade of Lithuanian independence. These different definitions of gender-based violence are reconstructed and presented in the different discourses of criminological knowledge and beliefs: a) the expert criminological discourse; b) the so-called discourse of the ‘well-informed citizens’; c) the so-called discourse of the ‘people from the street’. The theory of three different criminilogical discourses in Lithuanian crimininology is developed by Aleksandras Dobryninas but based on theoretical insights of Alfred Schütz. The article analyzes the third level from the perspectives‘ of the victims of gender-based violence.
ПОРЯДОК РОЗРАХУНКУ КВОТ ПІСЛЯ РЕФОРМИ МВФ: ЗМІНИ В ЄДИНОМУ ПАКЕТІ
Authors: БОРЗЕНКО Олена
Published: March 2020

Міжнародний валютний фонд зберігає плани щодо завершення перегляду своїх квот для країн у 2019 р. Квота країни у МВФ визначає розмір її фінансових зобов’язань перед Фондом, від неї залежить кількість голосів у Фонді та доступ країни до фінансування. Востаннє ці частки перерозподілялись у 2010 р. у рамках 14-го перегляду квот, коли сукупний капітал МВФ було збільшено на 100%, а на користь країн, що розвиваються, було передано 6% квот. Проте загальна частка країн, що розвиваються, становить у Фонді тільки 42,5%, решта (57,5%) належить розвинутим країнам. G20 раніше затвердила «дорожню карту», за якою до 2019 р. квоти країн – акціонерів у МВФ мають бути перерозподілені за новою формулою. Країни з економіками, що розвиваються, повинні отримати більше ваги у цьому інституті, створеному для підтримки фінансової стабільності його учасників, а традиційні акціонери – втратити свою частину. Проте раніше цю формулу погодити не вдалося через протидії США. Так, на даний час допустиме відношення обсягу боргу до ВВП у більшості країн переглядається у бік підвищення, причому ці зміни є найбільш помітними в державах з ринками, що формуються. Очікується, що для таких країн показник боргу може перевищити рівень, який спостерігався на початку глобальної фінансової кризи 2008–2009 рр. Уразливими залишаються і розвинуті країни, боргове навантаження яких перевищує 100% ВВП. Як наслідок, підвищується ймовірність тривалого збереження низьких темпів зростання ВВП. Свого часу "група Купера" відмовилася від використання показника боргу, вважаючи, що він може викликати певні "моральні проблеми": держави будуть заінтересовані в нарощуванні заборгованості з метою збільшення своєї квоти у МВФ.
РОЛЬ МВФ ЯК СУБ’ЄКТА ГЛОБАЛЬНОГО УПРАВЛІННЯ В РОЗВИТКУ СВІТОВОЇ ЕКОНОМІКИ
Authors: ПАНФІЛОВА Тамара
Published: March 2020

Обґрунтовано положення про те, що поширення кризових явищ у світовій економіці актуалізувало трансформаційні процеси в системі глобального управління, насамперед, щодо функцій і напрямів діяльності МВФ. Серед сучасних напрямів виокремлено: нагляд за міжнародною валютно-фінансовою системою; моніторинг економічної та фінансової політики держав-членів; зміцнення світової системи фінансової безпеки; координацію міжнародного співробітництва та інтеграції. Окреслено потенціальні ризики розвитку світової економіки, в тому числі щодо надвисокого рівня глобального боргу в цілому та його складових зокрема. Показано, що річні доповіді, квартальні огляди і прогнози, прес-релізи МВФ з узагальненими даними про основні тенденції розвитку світової економіки, її окремих регіонів і країн є дуже важливими як для наукового співтовариства, так і для владних структур.Підкреслено важливість формування нормативно-правового середовища регулювання фіскальної сфери як складового елемента архітектури глобального управління. Розкрито, що поширеним інструментом впливу міжнародних організацій є розроблення модельних (типових або рамкових) актів стосовно регулювання відповідної сфери відносин на національному рівні. Наведено характерні положення окремих актів фіскального характеру.Зазначено важливість для реформування сектору державних фінансів України положень і стандартів Кодексу належної практики із забезпечення прозорості в бюджетно-податковій сфері та Керівних настанов щодо управління державним боргом, розроблених міжнародними організаціями.
Suppression of Tumourigenicity 2 in Heart Failure With Preserved Ejection Fraction
Authors: Zach Veronika , Bähr Felix Lucas , Edelmann Frank
Published: March 2020

Heart failure (HF), with steadily increasing incidence rates and mortality in an ageing population, represents a major challenge. Evidence suggests that more than half of all patients with a diagnosis of HF suffer from HF with preserved ejection fraction (HFpEF). Emerging novel biomarkers to improve and potentially guide the treatment of HFpEF are the subject of discussion. One of these biomarkers is suppression of tumourigenicity 2 (ST2), a member of the interleukin (IL)-1 receptor family, binding to IL-33. Its two main isoforms – soluble ST2 (sST2) and transmembrane ST2 (ST2L) – show opposite effects in cardiovascular diseases. While the ST2L/IL-33 interaction is considered as being cardioprotective, sST2 antagonises this beneficial effect by competing for binding to IL-33. Recent studies show that elevated levels of sST2 are associated with increased mortality in HF with reduced ejection fraction. Nevertheless, the significance of sST2 in HFpEF remains uncertain. This article aims to give an overview of the current evidence on sST2 in HFpEF with an emphasis on prognostic value, clinical association and interaction with HF treatment. The authors conclude that sST2 is a promising biomarker in HFpEF. However, further research is needed to fully understand underlying mechanisms and ultimately assess its full value.
Large displacements of FGSW beams in thermal environment using a finite element formulation
Authors: Hoai Bui Thi Thu , Kien Nguyen Dinh , Huong Tran Thi Thu , Anh Le Thi Ngoc
Published: March 2020

The large displacements of functionally graded sandwich (FGSW) beams in thermal environment  are studied using a finite element formulation. The beams are composed of three layers, a homogeneous core and two functionally graded face sheets with volume fraction of constituents following a power gradation law. The material properties of the beams are considered to be temperature-dependent.  Based on Antman beam model and the total Lagrange formulation, a two-node nonlinear beam element taking the effect of temperature rise into account  is formulated and employed in the study. The element with explicit expressions for the internal force vector and tangent stiffness matrix is derived using linear interpolations and reduced integration technique to avoid the shear locking. Newton-Raphson based iterative algorithm is employed in combination with the arc-length control method to compute the large displacement response of a cantilever FGSW beam subjected to end forces.  The accuracy of the formulated element is confirmed through a comparison study. The effects of the material inhomogeneity, temperature rise and layer thickness ratio on the large deflection response of the beam are examined and highlighted.