bluuebunny/crossref_metadata_2025 huggingface dataset:
STUDY OF THE HYBRIDIZATION PROPERTIES OF MODIFIED OLIGONUCLEOTIDES BY MOLECULAR DYNAMICS APPROACH USING THE WEIGHTED HISTOGRAM ANALYSIS METHOD
Authors:   Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Yushin I.I. , Golyshev V.M. , Lomzov A.A. ,   Novosibirsk State University
Published: November 2023

The applicability of the molecular dynamics approach with trajectory analysis by the weighted histogram analysis method for calculating the thermodynamic parameters of duplexes formation of nucleic acid derivatives with DNA studied. Phosphoryl guanidine oligonucleotides and peptide nucleic acids were objects of the study. High efficiency of predictive calculation is shown.
INFLUENCE OF HUMORAL IMMUNE RESPONSE TO BACTERIOPHAGE ON PHAGE-THERAPY AND ANTI-BACTERIAL IMMUNITY
Authors:   Department of Natural Sciences, Novosibirsk State University, Allaf L.Al , Chechushkov A. , Ushakova T. , Morozova V. , Tikunova N. ,   Laboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk
Published: November 2023

We demonstrated that although phage therapy with PM16 leads to the formation of anti-phage neutralizing antibodies in balb/c mice, it may boost the organism humoral response against its host, p. mirabilis. On the other hand, injecting balb/c mice with p.mirabilis increases the level of anti-PM16 antibodies, even in mice without previous encounter with PM16.
NASAL VACCINE SALNAVAC AND SPUTNIK-V INDUCE AN INCREASE IN SERA AVIDITY AGAINST THE RBD DOMAIN OF SARS-COV-2 WITHIN SIX MONTHS AFTER REVACCINATION
Authors:   National Research Center Institute of Immunology of FMBA of Russia, Moscow, Astakhova E.A. , Baranov K.O. , Zuev E.V. , Poteryaev D.A. , Taranin A.V. , Filatov A.V. ,   Lomonosov Moscow State University,   Institute of Molecular and Cellular Biology SB RAS, Novosibirsk,   Generium, JSC, Moscow
Published: November 2023

Using a new method, biolayer interferometry (BLI), it has been shown that the new nasal vaccine Salnavac and Sputnik-V induce the affinity maturation of donor serum antibodies within six months after the vaccination.
Educação permanente em ambiente hospitalar: percepção da gestão de enfermagem
Authors: Santos Tatheanne da Silva Trindade dos , Gisi Maria Lourdes , Garbelini Maria Cecilia da Lozzo , Ribeiro Elaine Rossi
Published: November 2023

Objetivo: Desvelar a percepção da gestão em enfermagem sobre o processo de educação permanente. Metódos: Caracteriza-se por ser uma pesquisa exploratória-descritiva, com abordagem qualitativa, realizada mediante entrevistas com gestores de enfermagem, utilizando-se como critério para a pesquisa, o método de análise de conteúdo segundo Bardin L (1977). Resultados: A partir da análise das informações foi possível a integralização de sete categorias que confluíram na delimitação do fenômeno: Importância da educação permanente; Motivação; Papel dos gestores; Estratégias educacionais; Efetivação do programa na instituição, os pressupostos norteadores e as melhorias do programa de educação permanente na instituição. Conclusão Cada vez mais consciente de seus direitos, os usuários dos serviços de saúde exigem cuidados de saúde competentes, compassivos e humanos.  Assim, percebeu-se no estudo que a implementação do programa de Educação Permanente em Saúde com a finalidade de realizar mudanças nas relações, nos processos, nos atos de saúde e nos profissionais de saúde fornece uma base sólida para o atendimento de alta qualidade. Ainda, de acordo com o estudo, foi possível observar que os entrevistados acreditam no processo de educação como uma ferramenta de transformação no ambiente de trabalho, mas ainda com conceitos incipientes sobre o objeto em si.
Bimekizumab in Patients with Moderate to Severe Plaque Psoriasis: Analysis of Mental Health and Associated Disorders
Authors: Blauvelt Andrew , Armstrong April , Merola Joseph F. , Strober Bruce , De Cuyper Dirk , Peterson Luke , Davies Owen , Stark Jeffrey L. , Lebwohl Mark
Published: November 2023

Introduction: Patients (pts) with psoriasis have a greater risk of depression and suicidality than the general population.1 Here, we report Week (Wk)16 and longer-term depression and suicidal ideation and behavior (SIB) data in bimekizumab (BKZ)-treated pts with moderate to severe plaque psoriasis.

Procedure/study: The Patient Health Questionnaire (PHQ)-9, scored 0–27, measured depression severity monthly to Wk16 (regular intervals during BE BRIGHT open-label extension);2,3 higher scores indicate worse depression. PHQ-9 data were pooled from Wk0–16 of BE VIVID/BE READY (BKZ 320mg every 4 weeks [Q4W] vs. placebo [PBO]);4,5 3-year BE BRIGHT data are also reported.3 An independent Neuropsychiatric Adjudication Committee evaluated potential SIB treatment-emergent adverse events (TEAEs) and elevated PHQ-9 scores. Adjudicated SIB (suicide completion/attempt/ideation) incidence/100 pt-years (yrs; PY) was pooled from nine BKZ phase 2/3/3b trials in psoriasis, including up to 5 yrs’ exposure.3–11

Results: At Wk16, mean reduction from baseline in PHQ-9 with BKZ Q4W (N=670) vs. PBO (N=169) was 1.3 vs. 0.3; overall mean Wk16 scores were 1.2 and 2.4 for BKZ and PBO. Low mean BKZ PHQ-9 scores were maintained over 3 yrs of BE BRIGHT following the feeder studies (Wk144: 1.2). At Wk16, 92.9% of BKZ pts scored 0–4 in PHQ-9 (no/minimal depression) vs. 81.1% of PBO pts; 1.3% vs. 6.3% scored ≥10 (moderate–severe depression). Through Wk16, 0.7% BKZ vs. 4.1% PBO pts scored ≥15 (moderately severe–severe) in PHQ-9 at any visit. Over 7,166 PY of BKZ exposure (N=2,480), the rate of adjudicated SIB TEAEs was 0.126/100 PY.

Conclusion: PHQ-9 scores were low through Wk16 and remained low with longer BKZ exposure. The vast majority of BKZ pts had no/minimal depression at Wk16. The long-term incidence rate of adjudicated SIB with BKZ was low and similar to the general psoriasis population (range: 0.09–0.54/100 PY).1,12

Funding: UCB Pharma.
Periodontal vaccines: Where we are now and where we can go
Authors: Kohli Saksham , Singh Gunjan , Mathur Srishtee , Soni Pranjal , Siddqua Marrium
Published: November 2023

Edward Jenner devised and established the notion of vaccination in the late 18th century, using the cross-protection offered by the cowpox virus, which is not dangerous to humans. In adults, periodontal diseases with their multi-microbial etiology are a leading cause of tooth loss. Current treatment approaches have only been able to stop the disease’s progression; neither do they totally cure the condition nor stop it from returning. As a result, there is a need for more advanced therapeutic approaches, which may include vaccines that target potential periodontal bacteria. A boon to periodontics is the periodontal vaccination. No periodontal vaccine study has been able to fully meet all of the criteria for the ideal periodontal vaccine. The goal of the periodontal vaccination is to pinpoint the antigens implicated in the periodontitis damaging process that antibodies would be induced to guard against. In the future, periodontal vaccinations might become a supplement to mechanical therapy. To reduce the morbidity associated with periodontal disease in humans, eliminating the worldwide burden of periodontal disease would be the demanding primary function of any periodontal vaccination. This paper focuses on bringing to light the current approaches to periodontal vaccinations and what the future might have in store as far as this issue is concerned.
Adherence in adult orthodontic settings: Understanding orthodontists’ predictors
Authors: Al Shammary Nawaf Hamad , Alshammari Abdulrahman Khulaif
Published: November 2023

Objectives:

The objective of this study was to delve into predictors of adherence in adult orthodontic patients as stated by orthodontists in Saudi Arabia.

Material and Methods:

Ninety-one orthodontists from Saudi Arabia completed a questionnaire in relation to the importance and frequency of use of predictors of adherence. In this cross-sectional quantitative and exploratory study, orthodontists were requested to rate the predictors of adherence on a five-point Likert scale. The questionnaire in this study was categorized into four sections such as (1) evaluation – their opinion on the importance of predictor in the assessment of patient adherence, (2) application – scope of use of each predictor in the assessment of adherence in the routine practice, (3) open-ended questions to amass information about other apparent predictors of adherence, and (4) demographics.

Results:

Mixed and variable responses were obtained in terms of the importance and extent of application of predictors in assessing patient adherence. The survey revealed the most important predictors for adherence that included patient’s adherence to appointments and their cooperation in handling dental appliances, and maintenance of oral hygiene. However, in actual practice, orthodontists were frequently implementing factors such as the patient to keep appointments, the patient is observed to be involved in treatment, and the patient is observed to be enthusiastic about treatment. Through the open-ended questions, multiple factors were reported that need to be explored further. However, the remaining factors reported for adherence portrayed varied patterns.

Conclusion:

Predictors of adherence were reported with varying extent of consistency among orthodontists in Saudi Arabia. However, adherence to appointment, co-operation in handling of appliances, and oral hygiene emerged as the most significant factors by the orthodontists for adherence in cases of adult patients.
Idiopathic intracranial hypertension associated with polycystic ovarian syndrome, sensorineural hearing loss, and elevated inflammatory markers that lead to bilateral blindness: A case report with literature review
Authors: Zarei Sara , Kamali Setareh , Narinyan William , Nasouri Farnoush , Hassani Sara , Ibrahim Abdul Mahmoud , Zarei Rojeen , Altamimi Sadiq
Published: November 2023

Background:

Pseudotumor cerebri (PTC) or idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure without hydrocephalus or mass lesion, with normal cerebrospinal fluid (CSF) studies and neuroimaging. The exact cause remains uncertain, but potential mechanisms include increased CSF production, impaired CSF absorption, cerebral edema, and abnormal cerebral venous pressure gradients. Patients may present with various accompanying symptoms such as unilateral or bilateral visual obscuration, pulsatile tinnitus, back pain, dizziness, neck pain, blurred vision, cognitive difficulties, radicular pain, and typically intermittent horizontal diplopia.

Case Description:

We report a case of a 32-year-old female who initially presented with chronic headaches and oligomenorrhea, which resulted in the diagnosis of polycystic ovary syndrome (PCOS) a few years before the initial diagnosis of PTC. Despite receiving maximum medical treatment and undergoing optic nerve sheath fenestration, the patient experienced complete bilateral vision loss. Nearly 5 years later, the patient sought care at our outpatient neurology clinic, presenting with symptoms including tinnitus, left-sided hearing loss, and joint pain with elevated inflammatory markers and headaches. The focus of this research was to discuss the pathophysiology of each of these comorbidities.

Conclusion:

This case report aims to explore the pathophysiological relationships between PTC and concurrent comorbidities, including PCOS, sensorineural hearing loss, empty sella (ES) syndrome, and elevated inflammatory markers. Remarkably, no other PTC case with this unique constellation of concurrent comorbidities have been reported in existing medical literature. The case report underscores the critical importance of early diagnosis of IIH and prompt medical intervention, particularly in patients with PCOS experiencing chronic headaches.
Intracranial parenchymal capillary hemangioma: A case report
Authors: Sasaki Kosuke , Kuge Atsushi , Shimokawa Yu , Yamaki Tetsu , Kondo Rei , Sonoda Yukihiko
Published: November 2023

Background:

Capillary hemangioma is a rare benign hemangioma that occurs in the soft tissues of the skin, orbit, head, and neck. Intracranial cases, especially intraparenchymal cases, are extremely rare. In this study, we report the course of an intracranial parenchymal capillary hemangioma with left mild motor paresis and involuntary movements of the left upper extremity and was successfully treated by surgical resection, including radiological and pathological examinations.

Case Description:

This is a case of a 60-year-old woman who presented with motor weakness and involuntary movement of the left upper extremity. Computed tomography and magnetic resonance imaging revealed the right frontal hemorrhagic mass lesion without enhancement of contrast medium. Cerebral digital subtraction angiography showed no vascular stain and abnormal arteriovenous shunt. Preoperatively, we diagnosed cavernous hemangioma with a hemorrhagic component located in the right motor cortex. Because this case was symptomatic, we performed a craniotomy and gross total resection of the right frontal lesion. The diagnosis of capillary hemangioma was made by histological examination, including immunohistological study.

Conclusion:

Because intraparenchymal capillary hemangiomas are difficult to diagnose with preoperative imaging, surgical treatment, and histopathological examination are important.
City AND POWER IN ANCIENT RUS: THE FAILED UNION (HISTORICAL AND LEGAL RESEARCH)
Authors: Голубева Л.А. , Черноков А.Э.
Published: November 2023

Исследование становления государственности с позиций социальной антропологии, по мнению авторов статьи, дает возможность обосновать тенденции эволюции общественных отношений. Проведен анализ специфики эволюции древнерусской государственности, которая вызывает объективный интерес в настоящее время как повод для формирования определенных идеологических течений, дает возможность проследить зависимость политических отношений от уровня социально-экономической самостоятельности и грамотности населения. Согласно выводам, результат смешения западных и восточных элементов государственности имеет определенные последствия и в современности, несмотря на временную удаленность анализируемых событий.

According to the authors the study of the statehood formation from the social anthropology viewpoint makes it possible to substantiate trends in the evolution of social relations. The analysis of specifics of the evolution of ancient Russian statehood, which is of the objective interest nowadays as a cause for the formation of certain ideological trends, makes it possible to trace the dependence of political relations on the level of socio-economic independence and literacy of the population. The authors conclude that the mixing of Western and Eastern elements of statehood results in certain consequences also in modern times, despite the time remoteness of the analyzed events.
On Defining Legal Status of Artificial Intelligence
Authors: Грузинская М.А.
Published: November 2023

В статье исследованы основные концепции регламентации правового статуса искусственного интеллекта в правоотношениях. Проведен анализ каждой из точек зрения, выявлены их преимущества и недостатки. Установлен наиболее оптимальный способ закрепления правового статуса искусственного интеллекта в качестве самостоятельного субъекта права в отечественном законодательстве, а также определены перспективы его функционирования на территории Российской Федерации (РФ).

The article focuses on major concepts of regulation of legal status of artificial intelligence in legal relations. The paper presents analysis of each particular viewpoint with advantages and disadvantages thereof being revealed. The best method is set to legislate the legal status of artificial intelligence as a separate legal entity in domestic legislation and prospects are defined with regard to its functioning in the territory of the Russian federation.
Modern View of C. Schmitt’s Decisionism
Authors: Русаков С.С.
Published: November 2023

В статье рассматриваются некоторые аспекты политико-правового учения К. Шмитта, которые не только были актуальны в XX в., но и получили отражение в современных внутриполитических процессах. Автор анализирует ряд понятий, которые в децизионизме получили особое толкование, и подтверждает их примерами из современной правовой практики.

We look at certain aspects of Carl Schmitt’s political and legal doctrine that were seen as relevant in XX century and are currently reflected in modern internal political processes. We analyze a range of concepts having a special interpretation in decisionism and offer examples from modern legal practice to support the concepts in question.
Consumer Activity of Population as Indicator of State of Economy
Authors: Пыженкова Е.С.
Published: November 2023

В статье анализируются потребительская активность населения России и факторы, влияющие на нее. Оценивается влияние расходов домашних хозяйств на конечное потребление и темпы экономического роста. Анализируется динамика индекса потребительской уверенности и его составляющих.

We analyze the consumer activity of Russian population and factors affecting it. We assess the impact of household spending on final consumption and economic growth rate. The dynamics of consumer confidence index and its components is analyzed.
Quantum Particle-in-a-Sandbox: A video game that explores the time-dependent wave function for any arbitrary one-dimensional potential
Authors: Chulhai Dhabih
Published: November 2023

We present a tool, one that is both a stand-alone web-based video game and a Python package, designed for students to explore a particle’s wave function on one- dimensional potential surfaces. The tool relies on a basis set formalism and can there- fore explore any one-dimensional potential surface imaginable. This tool also lets students interact with the wave function and is the first of its kind to explore concepts such as the superposition principle and wave function collapse; its time-dependent na- ture shows how any wave function evolves over time allowing for exploration of other concepts such as the uncertainty principle. The video game’s ease of use makes these concepts accessible to anyone, without prior chemistry or programming background— though we expect that it would be most useful for undergraduate physical chemistry students and instructors. Preliminary use of QPiaS in a physical chemistry undergrad- uate course shows encouraging feedback regarding advancements in learning outcomes.
Synthesis of 1,3-disubstituted-[1.1.1]-bicyclopentane (BCP) salts: arylsulfonium, arylpyridinium and arylammonium isosteres
Authors: Monroe Harvey , Elsegood Mark , Teat Simon , Pritchard Gareth , Kimber Marc
Published: November 2023

Herein, we describe the synthesis of pyridinium, sulfonium and ammonium bicyclo-[1.1.1]-pentane salts as potential aryl isosteres. Arylsulfonium, ammonium and pyridinium salts are central motifs in several natural products, pharmaceuticals, and high value commodities within the industrial chemical sector. The reaction proceeds by a nucleophilic substitution on a bench stable precursor 1,3-diodobicyclo-[1.1.1]-pentane (DIBCP). The transformation displays broad substrate scope, good to excellent yield profile, with several of the BCP products being fully characterised by single crystal X-ray crystallography, highlighting the unique 3-dimensional structure of these potential isosteres. Finally, the pyridinium and quinolinium BCP salts can be cleanly converted into piperidinone and quinolone BCP analogues.
Improving Molecule-Metal Surface Reaction Networks Using the Meta-Generalized Gradient Approximation: CO2 Hydrogenation
Authors: Cai Yuxiang , Michiels Roel , De Luca Federica , Neyts Erik , Tu Xin , Bogaerts Annemie , Gerrits Nick
Published: November 2023

Density functional theory (DFT) is widely used to gain insight in molecule-metal surface reaction networks, which is important for a better understanding of catalysis. However, it is well known that generalized gradient approximation (GGA) density functionals (DF), most often used for the study of reaction networks, struggle to correctly describe both gas-phase molecules and metal surfaces. Also, GGA DFs typically underestimate reaction barriers due to an underestimation of the self-interaction energy. Screened hybrid GGA DFs have been shown to reduce this problem, but are currently intractable for wide usage. In this work we use a more affordable meta-generalized gradient approximation (mGGA) DF in combination with a non-local correlation DF for the first time to study a catalytically important surface reaction network, namely CO2 hydrogenation on Cu. We show that the mGGA DF used, namely rMS-RPBEl-rVV10, outperforms typical GGA DFs by providing similar or better predictions for metals, molecules, as well as molecule-metal surface adsorption and activation energies. Hence, it is a better choice for constructing molecule-metal surface reaction networks.
71Ga NMR Signatures of Lewis and Brønsted Acid Sites in Gallium Silicates Evidenced and Deciphered upon Interaction with Probe Molecules
Authors: Docherty Scott , Völker Laura , Yakimov Alexander , Verel René , Copéret Christophe
Published: November 2023

Determining the structure of Ga surface sites in Ga-based materials, used in catalysis, is critical for understanding their reactivity. However, obtaining molecular-level insights into their structure remains challenging. Here, using solid state Nuclear Magnetic Resonance (NMR) spectroscopy (71Ga, 31P and 15N), two different families of acid sites are identified in a gallosilicate material (Ga@SiO2), prepared via Surface Organometallic Chemistry and used as an efficient heterogeneous propane dehydrogenation catalysts or catalyst support. Through probe molecule studies using pyridine (Py) and triphenylphosphine oxide (TPPO), coupled with the synthesis of well-defined molecular analogs of surface sites and computational modelling on related cluster models using density functional theory, the Ga NMR signatures and the molecular structure of two types of sites, namely Brønsted acid sites and Lewis acid sites, are identified. These tetra-coordinate sites can be described as Ga sites bound to three anionic siloxide surface ligands along with a silanol or a siloxane bridge, respectively, each associated with specific NMR parameters, which change markedly upon interaction with Py or TPPO, thereby enabling their structural characterization.
Single catalyst double outer-sphere alkene cross-coupling
Authors: van der Puyl Lovett Vincent , Kong Lingran , Gan Xu-cheng , Shenvi Ryan
Published: November 2023

Cross-coupling catalysts typically react and unite functionally distinct partners via sequential inner-sphere elementary steps: coordination, migratory insertion, reductive elimination, etc. Here we report a single catalyst that cross-couples styrenes and benzyl bromides via iterative outer-sphere steps: metal-ligand-carbon interactions. Each partner forms a stabilized radical in-termediate yet hetero-coupled products predominate. The system is redox neutral and thus avoids exogenous oxidant, resulting in simple and scalable conditions. Numerous variations of alkene hydrobenzylation are made possible, including access to the privileged hetero-dibenzyl (1,2-diarylethane) motif and challenging quaternary carbon variants.
WERNER JAEGER: THE CONCEPT OF THE “THIRD HUMANISM”
Authors: Prokopenko Vladimir , Vorobiov Oleksiy
Published: November 2023

The article examines the development of the classical humanist tradition in German thought of the 20th century and the main figure of this tradition - Werner Jaeger. The authors analyze the situation in German classical studies at the beginning of the 20th century and conclude that the German project of classical philology, Altertumswissenschaft, was in a state of crisis at that time. Jaeger and his associates proposed a way out of this crisis with the help of the concept of "third humanism". "Third humanism" became a significant phenomenon in the spiritual movement of the beginning of the 20th century in Europe. Jaeger calls this humanism "third", because he considers the first humanism of the Renaissance, and the second - German humanism of the 18-19 centuries. The main principle of "third humanism" is the conviction that ancient culture not only had a great influence on the peoples of subsequent eras, but also became an eternal model of culture for all mankind. Humanism is a tradition through which antiquity can give us an impetus to preserve the "immutable values" embodied in Greek culture. Jaeger also analyzes the influence of ancient humanism on medieval Christian thinkers and argues that they drew on ancient political philosophy in their teachings about the church. The authors explain the fact that Jaeger's concept was not widely known for a long time because it was falsely associated with Nazi ideology in Germany in the 1920s and 1930s. The article presents arguments against this misunderstanding of the third humanism and all Jaeger's ideas. The final conclusions from the article indicate that the concept of the third humanism is a promising direction in modern classical studies, it can also become an effective strategy of cultural development, education policy, which is oriented towards humanistic goals. The authors also insist that the ideology of the third humanism can become a way to develop a truly humanistic policy in the modern world.
OS SABERES MATEMÁTICOS PARA MENINAS NO MARANHÃO: UM BREVE CONTEXTO A PARTIR DA PRIMEIRA LEI EDUCACIONAL BRASILEIRA DE 1827
Authors: Ribeiro Elke Rusana Pires Santos , Silva Antonio José da , Guimarães Marcos Denilson
Published: November 2023

Este artigo tem como objetivo analisar como os saberes matemáticos, destinados à instrução primária feminina, foram se consolidando ao longo do período Imperial, em especial, no Maranhão no final do século XIX. Para isso, buscamos conhecer o que estava prescrito na primeira lei educacional brasileira, de 1827, e que impactos os discursos sexistas de senadores daquela época tiveram sobre a formação de meninas. Este estudo é de natureza qualitativa, cujo referencial teórico-metodológico está inserido no âmbito das pesquisas da história da educação matemática e apoiado nas discussões da história cultural. As fontes examinadas foram documentos oficiais e estudos já realizados no âmbito da pesquisa histórica. Antes de a Lei Imperial de 1827 ser sancionada pelo imperador, debates sexistas dos senadores demonstram como esses homens determinaram qual deveria ser o papel da mulher na sociedade imperial. Os estudos das meninas ficavam limitados ao ler, escrever e contar, e às prendas domésticas, educando-as para serem futuras mães e esposas zelosas. No âmbito dos saberes matemáticos, elas ficaram excluídas do ensino de geometria e tiveram acesso somente às quatro operações fundamentais da aritmética. Verificamos, portanto, um currículo coerente com o patriarcado da época.
A mobile app for removing duplicate multimedia images
Authors: Manikant Thakur , Sankalp Tiwari , Vipin Yadav , Anand Khandare
Published: November 2023

With the development of multimedia technology and the popularity of smartphones, the collection of multimedia information from various applications has rapidly grown. This information encompasses text, images, video, and audio compositions. This multimedia information has not only transformed the way we communicate and share content but has also posed new challenges and opportunities in fields such as data analysis, content creation, and information management. Consequently, multimedia education has become the focal point for research institutions and businesses. The modern solution faces two main challenges: expensive uptime and comparative speed. Therefore, this study first introduces a washing method called Permutation (OPH) to reduce expensive working time. Furthermore, the study explores innovative techniques to enhance the comparative speed of the modern solution, ultimately aiming to achieve a more efficient and cost-effective system. With the OPH, a permutation wash (GOPH) has been developed, along with several useful techniques to address pressure changes. This development is based on the fact that most multimedia files differ from one another. A new hashing method, known as Hierarchical Permutation Hash (HOPH), has been created to enhance productivity. Extensive testing with real multimedia files clearly demonstrates that HOPH is five to seven times faster than Minis' while maintaining the same level of accuracy. HOPH achieves this remarkable speed improvement by efficiently leveraging hierarchical structures in data, making it a promising solution for a wide range of multimedia applications.
Investigation of alternative vehicle applications for reducing greenhouse gas emissions in urban public transport: The case of Adana province
Authors: ÜN Çağrı
Published: November 2023

Passenger cars, trucks, commercial airplanes, and railways all contribute to greenhouse gas emissions as part of the transportation sector. The usage of fossil fuels such as gasoline and diesel emits exhaust gases commonly referred to as greenhouse gases (GHGs) into the atmosphere. The buildup of these greenhouse gases in the atmosphere is responsible for global warming, a phenomenon that is becoming increasingly pronounced in today’s climate. In response to the GHG problem, cities have started setting targets to reduce their emission values. Adana is one of the cities that has set reduction targets. In all of the studies forming the basis of this research, the potential for transitioning buses and minibuses used in public transportation in Adana to alternative vehicles is investigated, with a focus on reducing greenhouse gas emissions. This study includes a comparison between electric, compressed natural gas (CNG), hydrogen and conventional vehicles, considering various parameters such as fuel economy estimates, vehicle size, and emission calculations. The research delves into greenhouse gas emission calculations specific to the Adana province, along with potential alternative applications in public transportation. Within the province, the transportation sector accounts for 27% of the total city inventory’s emissions. This study shows that converting the existing urban public transport fleet to alternative buses can lead an impressive reduction in greenhouse gas emissions as 81.93% with electric car, while hydrogen vehicles achieve a commendable 57.37% decrease. This underscores the substantial potential of electric and hydrogen-powered vehicles to lead to a significant reduction in transportation-related carbon emissions in the city. Consequently, the research places significant emphasis on addressing the transportation sector, which stands out as a primary contributor to emissions.
Szybkie samorództwo blagi. Schulz, Deleuze i kwestia interpretacji
Authors: Markowski Michał Paweł
Published: November 2023

The essay is a polemic against Idit Alphandary’s article, “Aesthetic Falsehood and Moral Emotions in Sanatorium Under the Sign of the Hourglass and The Hourglass Sanatorium.” The author notes that the strong interpretive theses of Alphandary’s article often turn out to be false, as they are based on Celina Wieniewska’s translation errors, as well as research presuppositions aimed at linking Schulz to Deleuze and Guattari’s category of “becoming-other.” Proving that the scholar took shortcuts in her interpretation, the author proposes a counter-interpretation according to which Schulz is no postmodernist, but a modern aesthetic conservative: in his vision, the world can only be saved by beauty. When beauty is removed from this world, life ceases to make sense, in view of which the only subject worth the effort is the subject of aesthetic contemplation. There is no deterritorialization in Schulz’s topology, instead there is an extremely strong aspiration for reterritorialization: for closure, for self-sufficiency, for autonomy, for slamming down the walls of the aesthetic fortress, for establishing a subjective center of the world that transforms reality into a delightful spectacle. Why does Alphandary misrepresent Schulz? Because she needs him as an ally in the common cause of aesthetic renewal of a world subjected to modern processes of secularization. She is not alone in this claim, for Schulz intensely attracts minds eager to view reality through the colorful panes of art. What the author fails to understand, however, is that this essentialist aesthetic utopia not only has nothing to do with the Deleuzian critique of the subject as a punctuated center of representation, but is its radical negation. Nor does she understand that modern aesthetic metaphysics (or metaphysical aestheticism) does not open the temporal horizon at all, but rather closes it (thus eliminating the transition to ethics), as evidenced by the image of the aesthetic fortress as a metaphysical asylum hinted at by Schulz in “The Republic of Dreams".
Modernistyczny oniryzm w dylogii Brunona Schulza i w noweli Jak we śnie Arthura Schnitzlera
Authors: Meniok Wiera
Published: November 2023

A post-psychoanalytic idea of Jacques Lacan that “Other is a lack inside me” helped the author to develop her interpretive strategy of conceptualizing onirism in Schnitzler’s “Dream Story” (Traumnovelle) and Schulz’s stories collected in Cinnamon Shops and Sanatorium Under the Sign of an Hourglass. In reference to Lacan’s concepts of the Other and the Real, she interpreted the plots, meanings, and the modernist paradigm of narration and the structure of subjectivity in the texts under scrutiny. Freud and Schnitzler believed that dreams and onirism are the most effective ways to make humans’ most intimate desires come true. Schnitzler’s “Dream Story” is a literary confirmation of Freud’s theory of dreamwork: the language of dreams opens up the space for manifestations of the characters’ unconscious and for the fulfillment of the impulses of their libido. Schnitzler’s story presents a sophisticated modernist plot combined with complex composition that demonstrates the dynamic structure of dreams. The borderline between consciousness and the unconscious is blurred, and the intrusion of the latter in the former deeply changes the life of the protagonists. Schulz’s fiction does not provide any answers to questions concerning the text’s idiom which is not a territory for affirming any theories, but is an intentional, pure phenomenon supplied by the senses as a “phenomenological perception” (Edmund Husserl). Schulz’s variant of onirism is not based on any linear order of the plot but remains a free-floating phantasy, a continuous blurring of the borderline separating consciousness and the unconscious, the overt and the covert, the real and the surreal. The language of Schulz’s stories is the unconscious as such, not a space for the realization of an individual unconscious. Referring to Lacan’s categories of the Other and the Real, the author interprets onirism in the Schulzean text as overcoming the trauma of the Real and the dream as trauma.
Mobility, Ephemerality and Tourist Economies: Graffiti Running Tours in León Guanajuato
Authors: Bruce Caitlin
Published: November 2023

In this paper, I examine the creation of a running tour showcasing commissioned Graffiti Art, or Urban Art, in León Guanajuato, Mexico. Set up in 2017, the tours are part of a larger economic and cultural shift away from the city's agricultural and industrial past. While seeking global city status since the 1990s, León is also trying to keep its traditional roots. Urban Art, as a form of creative expression, helps foster an appealing urban image. This paper argues that the tours highlight three critical issues that lie at the heart of the Creative City discourse and the institutionalization of graffiti, namely: Mobility; Ephemerality; The Economy.
Platformok, startégiák, dilemmák és a közös nevező : Mit hoz magával a Budapesti Gazdasági Egyetem 2027-ig szóló fejlesztési stratégiája?
Authors: Kétyi András
Published: November 2023

Jelen tanulmány az egyetem 2027-ig érvényes fejlesztési stratégiájának objektív szempontok szerinti rövid elemzésével foglalkozik, melynek szempontjai a következők voltak: a stratégia tartalmi pontjai, az időtáv, intézményi, illetve oktatói szempontok, valamint a digitalizáció és platformizáció, azon belül pedig a mesterséges intelligencia. A szempontokat objektíven számba véve kijelenthető, hogy a stratégiában a humánerőforrás-menedzsment (HR) szempontok dominálnak, a négyéves időtáv mérföldkövek kijelölése nélkül hosszúnak tűnik, az alulról érkező kezdeményezések támogatása hiányzik, az innováció egyedüli helyszínei a kutatóközpontok, a digitalizáció kevéssé hangsúlyos és nem terjed ki a platformizáció minden szakaszára, a mesterséges intelligenciát pedig teljesen figyelmen kívül hagyják.
A Lean-től a Green-en keresztül az ESG-ig
Authors: Besenyei Mónika , Budai László
Published: November 2023

A Lean & Green és az ESG (Environment, Social, Governance) két olyan megközelítés, amelyek a fenntarthatóság és a társadalmi felelősségvállalás terén nyújtanak iránymutatást. Mindkét kezdeményezés célja elsősorban az, hogy vállalatok és szervezetek pozitív hatást gyakoroljanak a környezetre és a társadalomra, miközben fenntartható gazdasági tevékenységet folytatnak. Az ESG és a Lean & Green szorosan összekapcsolódnak, hiszen mindkettő a fenntarthatóságra és a társadalmi felelősségvállalásra összpontosít. A Lean & Green elsősorban a logisztika karbonlábnyomának csökkentését támogatja, így hatékony eszköz lehet azon cégek számára, amelyek ezen iparágban érintettek és az ESG rendszer alkalmazására kötelezettek a közeli vagy távolabbi jövőben. Az ESG már most jelentős hatást gyakorol a pénzügyi eszközökön keresztül a nagyvállalatokra, de a közepes és kisebb vállalatok is igyekeznek felzárkózni, és nem csak a rájuk vonatkozó határidő közeledése miatt, hanem azért is, hogy megtarthassák a kedvező partneri pozíciójukat.
Turisztikai vállalkozások rugalmas ellenállási képességének vizsgálata
Authors: Debreceni János , Fekete-Frojimovics Zsófia
Published: November 2023

A 2020 tavaszán berobbanó események, a Covid-19 miatti járványügyi intézkedések, az azokból eredő kritikus forgalomcsökkenés addig nem tapasztalt kihívások elő állították a piaci szereplőket. A reziliencia a szervezetek azon képességét jelöli, hogy a kedvezőtlen helyzetekhez hogyan tudnak alkalmazkodni, illetve azokból milyen gyorsan tudnak felépülni. Jelen tanulmány egy, 2022 szeptembere és 2023 márciusa között, 107 turisztikai vállalkozás bevonásával végzett adatgyűjtés eredményeit mutatja be. A kutatás arra kereste a választ, hogy a vállalkozásokat mely készségeik segítették a Covid-19 alatt, mennyire felkészültek egy jövőbeli válsághelyzetre, mely külső kockázati tényezők veszélyeztetik leginkább működésüket, és milyen szerepet játszik a fenntarthatóság a felépülés utáni működésükben. A válaszokból kiderül, hogy a kutatásban résztvevőket leginkább a vállalkozás vezetésének ereje és minősége segítette a válsággal való megküzdésben, iparági kapcsolataikra azonban kevésbé számíthattak. A jövőbeli kedvezőtlen helyzetekre készülve tudatosan figyelik az iparági változásokat és képesek gyorsan, nehéz döntéseket hozni. Kritikus pontként jelennek meg azonban a kulcsemberek, akik szinte valamennyi esetben nagyon nehezen lennének helyettesíthetők a szervezeten belül.
Alkalmazott kutatással a gazdasági és társadalmi hatásért : Akciótanulás a felsőoktatásban
Authors: Dén-Nagy Ildikó , Király Gábor
Published: November 2023

A felsőoktatás egy olyan átmeneti periódusba érkezett, amikor a régi, bevált gyakorlatok többé már nem, vagy nem úgy működnek, mint akár néhány évtizeddel ezelőtt, ugyanakkor még hiányoznak a széleskörűen elterjedt, kiforrott, új megoldások. Az éppen zajló átalakulások közül tanulmányunkban elsősorban az oktatási formákban végbemenő változásokra koncentrálunk. Szembe állítjuk a hagyományos, jelenleg is meghatározónak számító deduktív tanulási utakat, illetve az ún. kínálati modellt az ezek alternatívájaként megjelenő induktív tanulási utakkal, valamint a keresleti/kompetencia modellel. Bemutatjuk az akciótanulást, mint korszerű pedagógia módszert, valamint megvizsgáljuk azt, hogy mennyire illeszkedik bele ezeknek a tipológiáknak az egyes kategóriáiba.
Az angol nyelvű szakmai kurzustartás tanári megfontolásai: egy nemzetközi kvalitatív kutatás tanulságai
Authors: Folmeg Márta , Kóris Rita , Fekete Imre
Published: November 2023

Az angol nyelvi szakmai kurzusok hatékony és sikeres megtartása módszertani kihívások elé állítja az oktatókat, amely az idegennyelvi készségeken túl számos pedagógiai/módszertani tudást, oktatói kompetenciát feltételez. Jelen tanulmány célja, hogy bemutassa az angol nyelvű szakmai kurzustartás (English-medium instruction, EMI) sajátosságait és módszertani ajánlásokat fogalmazzon meg az órák megtartásához. Hét különböző európai ország felsőoktatási intézményeinek EMI programjaiban tanító egyetemi oktatókkal készítettünk félig strukturált mélyinterjúkat, amelyek arra mutatnak rá, hogy az EMI kurzusok interkulturális kompetenciafejlődést eredményeznek mind az oktatók, mind a hallgatók körében, ugyanakkor kihívásokat jelentenek az oktatók számára az interkulturális érzékenység kialakítása és a kulturális különbségek kezelése terén.
Identification of Readiness to Participate in The Teacher Professional Program Chemistry Education Students
Authors: Retnowulan Sri Rahayu , Rosdalina Rosdalina , Damanik Irma Rezeki , Mellyzar Mellyzar , Chairani Riza Chourulliah , Rauzah Rauzah
Published: November 2023

This research aims to find out how prepared Malikussaleh University Chemistry Education students are in participating in the Professional Teacher Program (PPG) in order to become professional teachers. The type of research used in this research is quantitative descriptive. The subjects of this research were 29 alumni of Chemistry Education students at Malikussaleh University class 2015-2019, with techniques is probability sampling. Meanwhile, the object studied is readiness to take part in PPG with the six aspects reviewed, including: health aspects, interest aspects, motivation aspects, family environment aspects, socio-economic aspects and campus environmental aspects. The data collection technique in this research uses an instrument in the form of a questionnaire. Data analysis techniques use descriptive statistics with the help of applications Microssoft  Excel. And the results obtained from research on readiness to participate in PPG are that the health aspect has a percentage of 89% (very good), then the interest aspect has a percentage of 73% (good), then there is the motivation aspect which has a percentage of 53% (fair), then the family environment aspect which has a percentage of 77% (good), then the socio-economic aspect which has a percentage of 70% (good), and finally the campus environmental aspect which has a percentage of 68% (good). Based on the research results, it can be concluded that readiness to take part in the Professional Teacher Program is to become a professional teacher in the good category with an average percentage of these six aspects of 72%.
PENGARUH GAYA KEPEMIMPINAN TERHADAP KINERJA DENGAN MOTIVASI SEBAGAI VARIABEL MEDIASI PADA GURU SMKN 1 LINGSAR
Authors: Sari Ni Wayan Ratna , Asmony Thatok , Nurmayanti Siti
Published: November 2023

This study aims to determine the influence of leadership style (X), Work Motivation (Z) on Performance (Y) in SMKN 1 Lingsar Teachers. The type of research used is causal associative research with a quantitative approach. The data collection method used census method. The population and respondents in the study were 88 teachers. The analysis tool used is path analysis using the SPSS 26 for Windows program. The results of data analysis show that (1) leadership style has a positive and significant effect on performance. (2) Leadership style has a positive and significant effect on work motivation. (3) work motivation has a positive and significant effect on performance. (4) the role of work motivation positively and significantly mediates the influence of leadership style on performance in SMKN 1 Lingsar teachers.
AGRICULTURAL MARKETING IN INDIA
Authors:   Professor Of Economics, Annamalai University, B.V Dr. NARAYANASWAMY NAIDU
Published: November 2023

The phenomenal fail in the price of agricultural produce in recent years has drawn pointed attention to the problems of marketing of agricultural produce in this country; and it can scarcely be doubted that among various other operative causes, national and international, the lack of proper marketing fuci- lities in this country have an important share in bringing about this great landslide in prices. The fall in prices could have perhaps been minimised with better arrangements for marketing; at any rate it is beyond doubt that even in the most prosperous of times producers in this country were never able to get the maximum price for their products.
CERTAIN ASPECTS OF THE IRRIGATION POLICY OF THE MADRAS GOVERNMENT.
Authors:   Advocate Tinnevelly, A.S Mr.  KUPPUSWAMY AYYAR
Published: November 2023

Contribution for repairs to Irrigation Works from Ryotwari Land-holders. The Government's obligation to repair and maintain Irrigation Works serving ryotwari lands has been unquestioned till recently. But under G. O. 773 dated 2-5-33 and an order of the Board of Revenue passed in pursuance of the same (published in answer to question No. 711 in the local Legislative Council on 27--2-1934), this well accepted feature of Ryotwari administration has been substantially modified.
AN ECONOMIC ENQUIRY OF THE CULTIVATION OF PLANTAINS IN THE ERODE TALUK
Authors:   Tamil Nadu Agricultural University Coimbatore  641 003, N GANESHAMURTHY
Published: November 2023

It may be seen that the area under plantains has nearly doubled and with the present slump in the paddy market continuing and with the relatively better prices for plantains, the area under plantains is likely to increase. Soil. The wet-land soil of this tract is a sandy loam, well drained and the depth of the soil varies from 4 to 4½ feet. Years of manur- ing and cultivation have made the soils very fertile. The rich silt brought down with the irrigation water has also contributed to raise the fertility of the soil.
SATHGUDH-THE HOME OF SATHGUDI ORANGES
Authors:   Agricultural Demonstrator Gudiyattam, M GOPALAN UNITHAN
Published: November 2023

SATHGUDH (Sath-seven, Gudh-hillocks with forts) the place after which one of the best varieties of South Indian oranges is named, is now a hamlet of Pernambut Village, in Gudiyattam Taluk, North Arcot District. The remains of the seven hill fortresses are still seen on the tops of hills surrounding the village, the village proper being situated in the centre of a valley. Sathgudh, now gene- rally known as Satghur, is on the Pernambut-Synagunta forest road, a mile from Pernambut and the nearest railway station Mailpatti, on the Madras-Bangalore line, is eight miles away from the place. Originally it was the head quarters of the taluk of the same name, but now it has been reduced to the position of a hamlet due to adverse circumstances which will be described in the course of this note.