bluuebunny/crossref_metadata_2025 huggingface dataset:
Relevancia clínica de interacciones de antibióticos relacionadas con cambios en la absorción: revisión estructurada
Authors: Pino-Marín Daniel Esteban , Madrigal-Cadavid Juliana , Amariles Pedro
Published: March 2019

Introducción: durante el proceso de uso de los medicamentos es complejo establecer un esquema terapéutico eficaz y seguro, especialmente en los pacientes geriátricos, debido a la polimedicación. En este sentido, a medida que aumenta el número de medicamentos también aumenta la probabilidad de aparición de una interacción medicamentosa que podría tener consecuencias clínicas importantes. El objetivo de este estudio fue establecer y evaluar la relevancia clínica de las interacciones de antibióticos relacionadas con cambios en la absorción. Métodos: búsqueda en PubMed/Medline y Embase de artículos en inglés y español, acceso a texto completo, sin fecha límite, en humanos. La relevancia clínica se estableció con base a la probabilidad y la gravedad. Se identificaron 85 artículos, 46 informaron interacciones de antibióticos relacionadas con cambios en la absorción. Los resultados se orientaron en los antibióticos comercializados en Colombia, acorde con la base de datos del Instituto Nacional de Vigilancia de Medicamentos y Alimentos. Resultados: se identificaron 74 parejas de interacciones medicamentosas de medicamentos comercializados en Colombia, 63 fueron clínicamente relevantes y 11 con evidencia de ausencia de interacción. Conclusiones: la absorción de los antibióticos puede modificarse por factores como el uso simultaneo de medicamentos o alimentos; igualmente, los antibióticos pueden afectar la biodisponibilidad de algunos medicamentos, principalmente por modificaciones en la microbiota y generando interacciones clínicamente relevantes. El 67 % de las interacciones identificadas son de riesgo alto.
Pulmonary Vascular Disease in the Single-Ventricle Patient: Is it Really Pulmonary Hypertension and if So, How and When Should We Treat it?
Authors: Handler Stephanie S. , Feinstein Jeffrey A.
Published: March 2019

Despite significant improvements in the surgical and postoperative care for patients with single-ventricle physiology culminating in the Fontan circulation, significant late morbidity and mortality remains. In the setting of passive (ie, non-“pump” driven) pulmonary blood flow, pulmonary vascular resistance (PVR) plays a key role in determining cardiac output, and even slight elevations in PVR may result in significant morbidity. There is now great interest to treat Fontan patients with pulmonary vasodilators in an attempt to “optimize” PVR (and by extension, quality of life) and/or improve an elevated PVR. This review discusses the hemodynamic implications of the Fontan circulation, the evidence for use of pulmonary vasodilator therapy, and possible target physiologic mechanisms.
O uobecnieniu duszy, Sokratesie psychagogu i sztuce uświadomionego mówienia
Authors: Femiak Tomasz
Published: March 2019

W artykule podjęta jest próba intuicyjnej syntetycznej interpretacji sokratejskiej maieutyki w duchu psychologii homeryckiej. Bazując na tej interpretacji, opracowano ćwiczenie uświadomionego mówienia, które zostało włączone do zajęć akademickich: „Jak praktycznie wykorzystać własną głupotę? – doradztwo filozoficzne w warsztacie psychologa”, prowadzonych na Uniwersytecie Warszawskim i w Szkole Wyższej Psychologii Społecznej w latach 2004–2012. Na gruncie akademickim były to pierwsze w Polsce seminaria poświęcone doradztwu filozoficznemu. Podczas ćwiczeń studenci byli proszeni o zapisywanie swoich obserwacji. Niektóre ćwiczenia były filmowane. W ten sposób został zebrany bardzo ciekawy materiał, który może być podstawą do dalszych poszukiwań teoretycznych i empirycznych. W artykule krótko przedstawiam, czym jest uświadomione mówienie, prezentuję zapiski z ćwiczeń studentów oraz wskazuję na krótki materiał filmowy.
Simple bookkeeping model using Microsoft excel for culinary micro-business in East Nusa Tenggara Indonesia
Authors: Nino Indawati Jauhar , Manafe Janri Delastriani , Setyorini Tuti
Published: March 2019

The aim of the current research was to build a simple bookkeeping model using Microsoft Excel on culinary micro-businesses. It was applied research that was conducted in Kupang city, Indonesia. The sampling technique used was a saturated sample. The data analysis technique used was qualitative descriptive. The results of the study have shown that the problems faced by micro-businesses in Indonesia are related to business location, human resource, and capital. All the problems, cannot be denied, are related to financial records. The micro-entrepreneurs in Indonesia, in general, do not have good financial statements that can be used as a consideration for third parties who are willing to provide capital assistance. The current research presents the simple bookkeeping model created with the Microsoft Excel program that will greatly help micro-entrepreneurs this culinary in doing financial records properly and completely.
APPLICATION OF INTELLECTUAL ANALYSIS TOOLS FOR SOLVING WAREHOUSE OPERATION OPTIMIZATION PROBLEMS
Authors: Yakovlev R. N.
Published: March 2019

This work is devoted to the currently relevant issues - optimization of warehousing. Cargo receiving and dispatch processes held in a medium-sized warehouse are being considered in this work in detail. Based on the results of preliminary analysis, several indicators were selected, necessary for the usage of intellectual analysis tools in order to predict the required number of employees at the warehouse entrances. In accordance with the purpose set, models for predicting the required number of employees at the entrances were created to ensure the working process in a way, which corresponds to the optimal value of the indicator “workload of the entrance”. Various methods of machine learning, such as decision tree, k-nearest neighbors regression, random forest, and feedforward neural network are considered in the context of the problem, mentioned above. Each of the models was trained with different values of the model's hyperparameters, which were selected in both manual heuristic-based mode and using specialized software tools for grid search (GridSearchCV) from the scikit-learn library, designed to find the optimal values of the hyperparameters. Using the automated search for hyperparameters when training models yields to a smaller mean-square error in comparison with manual selection of hyperparameters. According to the analysis results of the model prediction quality, it was found that the predicted number of employees closely corresponds to the real situation in comparison with the planned values being used by the company. Based on the obtained results, several recommendations were made to assess the growth of the economic efficiency of the enterprise.
CONSIDERATION OF STOCHASTIC IMPACTS IN THE CONSTRUCTION SCHEDULING
Authors: Dobrosotskikh M. G.
Published: March 2019

There is show an experience of modern methods of scheduling in construction. There are reviewed existed scheduling methods: Critical Path Method, Constraints Programming, Job Shop Scheduling. Additionally there were reviewed methods with special edition for construction industry: shortest path planning, continue development frontline volume method, continue resources utilization method. All reviewed methods are simplified and don’t consider stochastic factors. Specific of the construction operation is a especially strong influence of stochastic factors to the construction production processes. There were reviewed methods of time reserve utilization, which appears in different stages of operations. This time reserve could be used, in particular, for minimization of negative aftereffects of stochastic factor influence on elements of construction. For these purpose was created target function of negative aftereffects minimization task, which describes dynamic and stochastic loses. The contribution of stochastic factors is expressed by exponential functions. There is shown, that redistribution of time reserve allows without any dynamic loses, to decrease contribution of stochastic loses. There is shown, that in approximation of independent works, the optimal schedule is that, which considers increasing of time reserve on critical directions. There is showed on individual example of algorithm for negative factors aftereffect minimization. Using this algorithm allows to make schedule with details of minimal approximated stochastic loses. In opposite, having a possibility of resources redistribution to directions, associated by high risks and loses, the optimal schedule plan will be alternative schedule plan, considering a possibility of operative redistribution, even through risks rise on non-critical directions.
Influence of Health Literacy on Effects of Patient Rating Websites: Survey Study Using a Hypothetical Situation and Fictitious Doctors (Preprint)
Authors: Schulz Peter Johannes , Rothenfluh Fabia
Published: March 2019

BACKGROUND

Physician rating websites (PRWs) are a device people use actively and passively, although their objective capabilities are insufficient when it comes to judging the medical performance and qualification of physicians. PRWs are an innovation born of the potential of the Internet and boosted very much by the longstanding policy of improving and encouraging patient participation in medical decision-making. A mismatch is feared between patient motivations to participate and their capabilities of doing so well. Awareness of such a mismatch might contribute to some skepticism of patient-written physician reviews on PRWs.

OBJECTIVE

We intend to test whether health literacy is able to dampen the effects that a patient-written review of a physician’s performance might have on physician choice.

METHODS

An experiment was conducted within a survey interview. Participants were put into a fictitious decision situation in which they had to choose between two physicians on the basis of their profiles on a PRW. One of the physician profiles contained the experimental stimulus in the form of a friendly and a critical written review. The dependent variable was physician choice. An attitude differential, trust differential, and two measures of health literacy, the newest vital sign as an example of a performance-based measure and eHealth Literacy Scale as an example of a perception-based measure, were tested for roles as intermediary variables. Analysis traced the influence of the review tendency on the dependent variables and a possible moderating effect of health literacy on these influences.

RESULTS

Reviews of a physician’s competence and medical skill affected participant choice of a physician. High health literacy dampened these effects only in the case of the perception-based measure and only for the negative review. Correspondingly, the effect of the review tendency appeared to be stronger for the positive review. Attitudes and trust only affected physician choice when included as covariants, considerably increasing the variance explained by regression models.

CONCLUSIONS

Findings sustain physician worries that even one negative PRW review can affect patient choice and damage doctors’ reputations. Hopes that health literacy might raise awareness of the poor basis of physician reviews and ratings given by patients have some foundation.
Kekuatan genggam tangan, skor Child Pugh, dan massa otot pada pasien dengan sirosis hati
Authors: Hardigaloeh Amanda Trixie , Gani Rino Alvani , Hasan Irsan , Sulaiman Andri Sanityoso
Published: March 2019

Background: Malnutrition is independent factor related to morbidity, mortality and high cost of treatment in liver cirrhosis. Hand grip strength (HGS) is one of the method use for malnutrition detection and prognosis evaluation. The correlation of HGS with liver function (Child Pugh score) and muscle mass is controversial. These important evaluation is not yet avalaible in Indonesia.Objective: Aim of this study is to assess the role of HGS measurement in malnutrition and its correlation with liver function and muscle mass.Method: This is a cross-sectional study in liver cirrhosis patients at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital from February to June 2015. Nutritional status was assessed by HGS. Muscle mass was obtained from bioimpedance. Data were analyzed using Spearman correlation test.Results: There were 115 patients liver cirrhosis at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital, 112 patients who fit the inclusion criteria, consisted of 79 men and 33 women with mean age 54.15±10.55 years, median Child Pugh score 6 (5-13) with median HGS 26 (11-50) kgF, mean muscle mass 44.43±8.12 kg. The median intake of energy 1334.82 (604.75-3023.7) kkal, median protein 45.87 (19-114.5) gram. Prevalence of malnutrition according HGS was 33%. Hand grip strength is not correlated with Child Pugh score (p=0.046; r=-0.19) however it is correlated with muscle mass (p<0.00; r=0.70).Conclusion: There are 33% malnutrition cases based on HGS in out patient liver cirrhosis. There is no correlation between HGS with Child Pugh score however HGS is correlated with muscle mass in liver cirrhosis.
Introducción al estudio de los hongos superiores
Authors: Lazo Waldo
Published: March 2019

En este trabajo, destinado a facilitar la identificación de los géneros de los hongos superiores más comunes en la zona central y algunos de la zona sur deChile, se exponen las características más significativas de las fructificaciones fúngicas.
Susceptibilidad in vitro de dermatofitos, candida y otros hongos frente a Natamicina
Authors: Zaror L. , Gutiérrez M. A. , Sáez F. N.
Published: March 2019

Se investigó la actividad cuantitativa in vitro de Natamicina, un polieno de amplio espectro, frente a 98 cepas de Dermatofitos, Candida y otros hongos, aislados de muestras clínicas en Valdivia, Chile.Los resultados obtenidos muestran que el 100% de las cepas de Microsporum canis fue susceptible a 2S microgramos o menos y el 93,7% a 12,5 microgramos de Natamicina por ml. de agar.Trichophyton mentagrophytes fue inhibido en un 84,1% a 25 microgramos de Natamicina y Trichophyton rubrum, el 100% a 25 microgramos por ml. de agar.Candida albicans fue inhibida en un 85 y 100% respectivamente a C.I.M. de 6,25 y 12,5 microgramos de Natamicina por ml. de agar.
Tinea nigra contracted in Spain
Authors: Fischman O. , Soares E. C. , Alchorne M. M.A. , Baptista G. , Camargo Z. P.
Published: March 2019

Se relata un caso de tinea nigra diagnosticado en Sao Paulo (Brasil) en una paciente española de 4 años de edad. Por sus características morfológicas el agente fue clasificado como Exophiala werneckii. De acuerdo con la revisión de la literatura europea, probablemente sea este el primer caso de tinea nigra de España comprobado micológicamente.
ALTERATION OF CYP3A1 mRNA LEVEL IN PRIMARY RAT HEPATOCYTES IN RESPONSE TO AMPK ACTIVE ATOR AICAR
Authors: Lee Bang-Sub , Kim Jooyoung , So Wi-Young
Published: March 2019

Background and Objective

AMP-activated protein kinase (AMPK) functions as a sensor of the intracellular energy status that can be stimulated by a synthetic activator, 5-aminoimidazole–4–carboxamide–1–beta–D–ribofuranoside (AICAR), which is used to replicate the effect of physical exercise in hepatocyte embryoid bodies. This study investigated the effect of AICAR on the CYP3A1 mRNA expression in primary hepatocyte embryoid bodies derived from a rat liver.

Material and Methods

The primary hepatocytes were isolated from a male Sprague Dawley (SD) rat (215 g) and subjected to the following treatments: control without AICAR (CTL, n=3), 1 μM AICAR (n=3), 10 μM AICAR (n=3), and 100 μM AICAR (n=3). RNA was isolated and used as the template for synthesizing cDNA by reverse transcriptase to perform quantitative PCR (qPCR). The independent samples t-test was conducted to examine differences between groups. Statistical significance was set at p<0.05.

Results

The qPCR analysis demonstrated that CYP3A1 mRNA expression in primary hepatocyte embryoid bodies significantly increased in the presence of 10 μM (t=1.730, p<0.05) and 100 μM AICAR (t=3.207, p<0.05) as compared to that in the control group hepatocytes. However, the observed increase of CYP3A1 mRNA in hepatocyte embryoid bodies was not statistically significant in the presence of 1 μM AICAR as the lowest test concentration.

Conclusion

In this study, we demonstrated that AICAR, an AMPK activator, can increase the expression of CYP3A1 mRNA in primary hepatocytes. Future studies should assess the effect of AICAR treatment on CYP3A4 in human hepatocytes.
Studi Kelayakan Pembangkit Listrik Tenaga Mikrohidro (Pmlth) Pada Saluran Irigasi Gunung Bunder Pamijahan Bogor
Authors: Prabowo Yani , B Swasti , Nazori Nazori , Gata Grace
Published: March 2019

Listrik saat ini sudah menjadi salah satu kebutuhan manusia, berbagai macam cara dilakukan oleh manusia untuk mendapatkan energi listrik baik itu yang berasal dari sumber energi yang tidak terbarukan atapun yang berasal dari sumber energi terbarukan. Energi listrik berasal dari sumber energi terbarukan saat ini menjadi tren untuk dikembangkan banyak negara. Pembangkit listrik yang berasal dari sumber energy terbarukan biasanya disesuaikan dengan potensi daerah tersebut. Desa Gunung Bunder, Pamijahan Bogor salah satu desa yang berbatasan dengan hutan lindung gunung halimun, mempunyai potensi alam berupa aliran sungai yang belum dimanfaatkan sebagai pembangkit listrik tenaga air. Melalui penelitian ini, dilakukan survei terhadap potensi yang ada pada wilayah direkomendasikan menjadi sebuah pembangkit lisrik mikrohidro dan menentukan jenis turbin yang cocok untuk wilayah tersebut. Pada Desa Gunung Bunder sampai saat ini ada wilayah yang belum teraliri jaringan listrik karena medannya tidak memungkinkan untuk dialirin listrik dari PLN. Potensi yang berhasil didapat dari penelitian ini dengan beda ketinggian (head) 2.6 meter dari panjang lintasan 4 stasiun dengan jarak masing masing antar stasiun 26 meter.  Kecepatan air rata-rata 10 liter perdetik akan menghasilkan daya sebesar 254.604 watt. Dilihat dari data hasil pengamatan dilapangan dan kontur sungai yang cenderung datar direkomendasikan menggunakan turbin jenis Kaplan yang dimodifikasi menjadi turbin vortex.
Evaluasi Kualitas Informasi Sistem ERP Studi Kasus pada PT XYZ
Authors: Djahidin Danny Y.
Published: March 2019

Evolusi sistem informasi ditandai dengan pengembangan pendekatan baru untuk mengakses informasi yang dipengaruhi oleh evolusi bahasa, budaya, dan juga perilaku. Namun perkembangan cepat teknologi informasi tidak diimbangi oleh kualitas informasi yang dihasilkan, sehingga muncul berbagai permasalahan. Oleh karena itu evaluasi atas kualitas informasi yang dihasil perlu dilakukan untuk menilai apakah sistem yang telah diimplementasikan memberikan para penggunanya informasi yang sesuai dengan harapan atau tidak. Miller (1996) mengatakan bahwa dalam melakukan penilaian terhadap kualitas informasi diperlukan 2 langkah yaitu (1) menyorot atribut yang penting dan (2) menentukan bagaimana atribut ini penting bagi pengguna. Kriteria yang ditemukan dari hasil studi literatur adalah subject menekankan pada pemahaman pengguna atas informasi, object menilai bagaimana sistem dapat menghasilkan informasi yang mudah diakses, komplit serta aktual, sedangkan process memberikan penilaian mengenai bagaimana informasi dapat disampaikan secara cepat, tepat waktu dan akurat. Kriteria-kriteria tersebut digunakan untuk mengevaluasi kualitas informasi sistem ERP pada PT XYZ, dimana para pengguna menilai baik kualitas informasi yang dihasilkan, yaitu 100% untuk kriteria subject, 92% pada kriteria object, dan 88% untuk kriteria process. Dengan hasil evaluasi ini disimpulkan bahwa sistem telah menghasilkan informasi sesuai dengan harapan pengguna
PERANGKAT WIRO 1.0 SEBAGAI ALAT BANTU PROSES PENGUMPULAN INFORMASI WIFI
Authors: Supriyatno Gigih , Siswanto Budi
Published: March 2019

Information gathering activities are currently implemented with laptop equipment and external antennas. Such a device may cause suspicion that leads to personnel vulnerabilities in the field. This research will discuss about the design of equipment that is more flexible and small to support information gathering activities of wifi signal analysis by utilizing Rasberry Pi device as a replacement for laptop devices. The research method begins by describing how data retrieval works through wifi, how the Rasberry Pi works and then designing the device and the software system used.This design produces a special wifi signal gathering device pack 4-way handshake that has smaller dimensions, practical, avoid suspicion and able to operate automatically.
Tourism Perception Of General Toilet Hygiene In Objects And Tourist Attractions In Bali
Authors: Sunarsa I Wayan , Andiani Nyoma Dini
Published: March 2019

This study aims to determine the perception of tourists on the cleanliness of public toilets in Tourist Objects and Attractions in Bali. The population of this study is all public toilets that are spread on the attractiveness of tourism in all districts and cities in Bali. The toilet samples used were 20 public toilets and a sample of 10 respondents from each toilet or equal to 200 people. Data collection methods used are interviews, observations, and questionnaires. Data analysis techniques used are qualitative descriptive and analysis of interest and performance levels. The results showed that tourists' perception of the cleanliness of public toilets on tourist objects and attractions in Bali was 2.18, which meant that the toilets were less clean. Tourist comments show smelly, dirty toilets, no tissue and no soap. The level of suitability between experience and tourist expectations of cleanliness and public toilet facilities at tourist attractions in Bali is 47%. This shows that only 47% of tourist expectations can be met. While the remaining 53% cannot be fulfilled
PENGUJIAN USABILITY PADA SISTEM INFORMASI PANGKALAN DATA DOSEN DAN KINERJA DOSEN UNDIKSHA MENGGUNAKAN METODE QUESTIONNAIRE AND FIELD OBSERVATION
Authors: Antari Kadek Widya , Arthana Resika , Sugihartini Nyoman
Published: March 2019

Undiksha has several systems incorporated in e-ganesha, including the Lecturer Database Information System (PDD) and the Undiksha Performance System. This system is used for accessibility of lecturer data and for recording lecturer performance in the implementation of Tri Dharma College. The objectives of this study were (1) to determine the level of usability in Lecturer Database Information System and Undiksha Lecturer Performance Using the Questionnaire and Field Observation Method (2) to find out the recommendations of Lecturer Database Information System and Undiksha Lecturer Performance to increase user satisfaction based on results from the research that will be conducted. The variables measured in this study are effectiveness, efficiency, and user satisfaction. With the Field Observation method to measure aspects of Effectiveness and efficiency, the SUS questionnaire was used to measure aspects of user satisfaction. The sample used was 25 respondents of PNS lecturers who were still active. The results of usability testing on the Undiksha PDD system show that (1) the system is still not effective with an average task completion of 64.96%, (2) the system is not efficient because the user is still confused with the PDD Undiksha system (3) the user is not satisfied using the PDD Undiksha system seen from the results of the SUS questionnaire which is 61.6% less than the SUS standard which is 68%. The results of usability testing in the Undiksha Performance system show that (1) the system has not been effective with an average task completion of 60.16%, (2) The system has not been efficient because many users have not been smooth and still confused using the Undiksha Performance system (3) Users not satisfied with using the system seen from the results of SUS which is 61.5%. Recommendations for improvements provided are derived from the results of video analysis using observation sheets on field observation methods, HCI theory and 8 golden rules, and expert tests and expert input have been carried out.
Software for Crawling and Analysis of Ego-Network Graphs from Social Networking Services
Authors: Chesnokov V. O.
Published: March 2019

Online social networks are one of the main platforms for arbitrary subjects of discussion. They are one of the main sources of data to analyse public opinion. For crawling and analysis of data from online social networks, are used data monitoring systems, which include a data collecting system. A typical system for collecting data from the Internet contains a crawler, parsers, a collection queue of tasks, a task scheduling subsystem, and a module for writing structured data to a storage system. The crawling from online social networks has a number of features. The paper considers methods of access to data from online social networks and a task planning subsystem. Formulates and underpins the requirements for a data collecting system to provide crawl results from online social networks, namely scalability, extensibility, and availability of a data storage subsystem and a queue of collection tasks.

Describes main data accessing methods to have information from online social networks: API-based access, access through processing of HTML-pages and specialised interfaces for bots. Provides a description of main restrictions, which an online social network imposes, namely the need to register the application, the limited number of requests, the need to obtain user‘s permission to collect his (her) data. According to the analysis results, the anonymous download and processing of HTML pages were chosen, as a data access method.

Formulates the task subsystem requirements, namely available types, hierarchy, and context of the task to be done. Describes the general architecture of the developed software system for crawling and analysis of data from online social networks, justifies its compliance with the earlier raised requirements.

The problem of crawling and analysis of users’ ego-network graphs (sub-graphs of a social graph) are considered. Their collecting features are described and options of implementation are proposed depending on the amount of data collected.

The results obtained can be used to build monitoring systems for online social networks and collect test data for experimentally estimated algorithms of social graphs analysis. Further development may be concerned with a detailed consideration of the problems of collecting other types of data from online social networks.
Soil Physical Properties Enhancement Via Native Tree Species in Northern Ethiopia
Authors: Legese Kassaye Gurebiyaw , Gelanew Abay , Alemu Melese
Published: March 2019

Dozens of chemical fertilizer is produced in factors to maintain and reclaim soil fertility, but the reliance on artificial fertilizer alone is not advisable due to environmental pollution. . Thus, indigenous plant species can maintain soil fertility without any extra cost. The aim of this study was to examine the effect of indigenous tree species on soil physical properties. Three dominant indigenous trees species (Croton macrostachuys, Cordia Africana and Albizia gummifera) were considered.  Soil samples were taken from different sampling points under crown of these tree species (mid of crown and edge of crown). One sampling point is included by far 30m from the selected tree as a control group. Soil sample was taken by using core sampler. Soil physical properties such as texture, structure, porosity, bulk density and moisture content were analyzed. Bulk density was determined as 0.73g/cm3, 0.75g/cm3 and 0.8g/cm3 for Albizzia gummifera, Croton macrostachuys and Cordia Africana respectively. Bulk density was very small under crown of all trees as influenced by the amount of organic matter falling from trees leaf. The texture under crown of all tree species (silty loam, loam and loamy sand) is quite better for agriculture purpose than control point. Soil color under crown is in the range of brown to black color, which indicates high fertility level. Soil porosity was very high under the crown of all tree species as compared to the control site. It is determined as 72.5%, 71.6%, and 69.7% for Albizzia gummifera, Croton macrostachuys and Cordia Africana respectively. Soil consistence, porosity and moisture content were better under crown of the trees than control group. Soil properties under the crown of indigenous tree species were better than bare land soils.  Therefore, indigenous trees are promising option to maintain soil fertility level and land owners ought to be aware of this miracle.
Attitude Towards Humanoid Robots and the Uncanny Valley Hypothesis
Authors: Łupkowski Paweł , Gierszewska Marta
Published: March 2019

The main aim of the presented study was to check whether the well-established measures concerning the attitude towards humanoid robots are good predictors for the uncanny valley effect. We present a study in which 12 computer rendered humanoid models were presented to our subjects. Their declared comfort level was cross-referenced with the Belief in Human Nature Uniqueness (BHNU) and the Negative Attitudes toward Robots that Display Human Traits (NARHT) scales. Subsequently, there was no evidence of a statistical significance between these scales and the existence of the uncanny valley phenomenon. However, correlations between expected stress level while human-robot interaction and both BHNU, as well as NARHT scales, were found. The study covered also the evaluation of the perceived robots’ characteristic and the emotional response to them.
Analysis of facial expression movements and the phenomenon of frontal asymmetry as the basis for automation of the research of hidden cognitive attitudes. Some basic remarks
Authors: Sołoducha Krzysztof
Published: March 2019

The aim of this text is to show how, using the achievements of modern computer science, psychology and neurobiology, we can search for an answer to the question about the a priori mechanisms of shaping a phenomenal image of reality given by experience. This phenomenalism statement is very close to, so called, Bayesian model of mind by Karl Friesen. The author asks how in massive scale to reach the cognitive processes taking place without representation, outside the field of consciousness, which influence the formation of this model of the world. The result of the consideration is to be a neuromachine project whose task will be to automate and mass research of hidden cognitive attitudes. Its activity is to become a real alternative to opinion polls performed in the paradigm of the so-called declarative sociology, which do not provide results significantly reducing the risk of decision-making in management.
The Engineering Project Organization Society and megaprojects: literature analysis using keywords
Authors: Ceric Anita , Sertic Josip
Published: March 2019

The purpose of this paper is to analyze how the Engineering Project Organization Society (EPOS) has addressed the issue of megaprojects at their annual conferences organized from 2006 to 2016. The literature analysis used in this paper is a form of content analysis. It focuses on the usage of a particular term in scientific papers. In this case, the key term is “megaprojects” or “mega-projects”. Papers in which this term appears are selected for further analysis. The findings show that the main keyword “megaproject” or “mega-project” appears 22 times in the identified papers. It appears in 10 titles and nine abstracts. Most important for this literature analysis, it appears in seven lists of keywords. Literature analysis proceeded by analyzing the associated keywords in the seven papers in which the main keyword “megaproject” or “mega-projects” can be found in the listed keywords. The analysis shows that the main associated keywords are “governance”, “complexity”, and “trust”. This research provides a view of the collective understanding of megaprojects within the EPOS community and helps to shape further research in this field. In addition, the results of this research can be seen as a step forward for scholars and practitioners to discuss and develop a new theoretical framework for better understanding of megaproject governance.
Biological age and its role in stratification of cardiac risk
Authors: Shikhverdiev N. N. , Ushakov D. I. , Peleshok A. S. , Krivopalov V. A. , Sizenko V. A.
Published: March 2019

Risk stratification in elderly patients is very important, as none of the applied models for the prediction of mortality in cardiac surgery does not take into account the whole complex of physiological features of the aging organism.

Theobjectivewas to analyze the effectiveness of the method of qualitative assessment of biological age.

Material and methods.Our study included 127 patients (87 male and 40 female) aged 65 to 84 years (mean age – 72.2±4.7 years) who underwent elective cardiac surgery. Perioperative factors were analyzed. The primary endpoint of the study was a 30-day mortality rate.

Results.The total 30-day mortality rate was 13.4 % (17 patients). Perioperative predictors of 30-day mortality rate were the calculated values of the CAF scale (p=0.006), the surgery volume (p=0.044), the use of extracorporeal blood circulation (p=0.048).

Conclusion.The use of qualitative assessment of biological age allows to more accurate predict the mortality in cardiac elderly patients.
Photodynamic therapy for R1 lung cancer resections
Authors: Akopov A. L. , Rusanov A. A. , Kazakov N. V. , Papaian G. V. , Chistiakov I. V.
Published: March 2019

Theobjectivewas to evaluate the effectiveness of endobronchial photodynamic therapy (PDT) for preventing a non-small cell lung cancer (NSCLC) relapse after R1 resection with positive bronchial resection margins.

Material and methods.This study included 17 patients. The planned morphological diagnostics revealed the presence of tumor cell complexes at the bronchial resection margins in 5 (29 %) patients (cancer in situ – 2, invasive cancer – 3), in peribronchial tissues – in 5 (29 %) patients, in lymphatic vessels at the resection margins – in 7 (41 %) patients.

Results.All patients underwent one session of endobronchial PDT as an adjuvant treatment. No complications of PDT were noted. The five-year observation revealed a relapse at the bronchial stump area in 1 patient only (6 %). 16 (94 %) patients lived for 1 year, 12 (71 %) patients – for 5 years. Long-term results were significantly worse in patients with tumor complexes in lymphatic vessels at the bronchial resection margins (5-year survival rate – 29 %, p=0.04), with pN2 (0 %, p=0.01), lung adenocarcinoma (20 %, p=0.03).

Conclusion.The use of endobronchial PDT as an adjuvant treatment for patients with NSCLC after R1 resection with positive bronchial resection margins is simple, safe and characterized by good immediate and long-term results.
The influence of burdened comorbid status on treatment outcomes of injured elderly patients with severe traumatic brain injury
Authors: Shcherbuk Ju. A. , Zakharov V. I. , Shcherbuk A. Ju. , Donskov V. V. , Cherepanova E. V. , Iakovlev A. A. , Sergeeva T. V. , Iakovleva M. V.
Published: March 2019

Theobjectivewas to research the effect of burdened comorbid status on the course of severe traumatic brain injury (TBI) in the elderly.

Material and methods. 243 injured elderly patients (182 men and 61 women) with severe TBI and burdened comorbid status.

Results. It was found that the postoperative period was characterized by more severe course of injury associated with the development of infectious and inflammatory complications.

Conclusion. Early medical rehabilitation does not have a significant impact on the state of comorbid status, but is important in the prevention of infectious and inflammatory complications due to the early activation of the victims and the elimination of hypodynamia in intensive care and neurosurgical departments.
Prevention of postoperative complications and recurrence of anterior abdominal wall hernias in patients with metabolic syndrome
Authors: Antonova N. A. , Lazarev S. M.
Published: March 2019

Theobjectivewas to show the preventive principles of postoperative complications of anterior abdominal wall hernias in patients with metabolic syndrome.

Material and methods.The authors analyzed the surgical treatment with tension-free plasty and prosthetic mesh in 162 patients with metabolic syndrome.

Results.Pathogenetically grounded preoperative normalization of parameters of metabolic syndrome, conducting of anticoagulant and antibiotic therapy, using of lower limb compression and observation by the surgeon during the postoperative period reduced the percentage of postoperative complications to 11,1 %, in contrast to the group of patients where prevention was not carried out, complications accounted for 37,5 %.

Conclusion.Surgical patients with metabolic syndrome need to normalization of their parameters in the preoperative period, as well as the appointment of anticoagulants and antibiotics during their hospitalization.
Professor Sergei Petrovich Fedorov (1869–1936) (on the 150th anniversary of the birthday)
Authors: Maistrenko N. A. , Romashchenko P. N. , Kurygin A. A. , Semenov V. V.
Published: March 2019

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Venous thromboembolic complications
Authors: Khubulava G. G. , Gavrilov E. K. , Bolotokov H. L. , Sadovoy S. V.
Published: March 2019

The article is devoted to the current issues of diagnosis of deep vein thrombosis of the lower extremities, provides updated recommendations on the choice of drugs in the treatment of deep vein thrombosis of the lower extremities in various clinical situations
Marmara Denizi, Bandırma Körfezi sarıkuyruk istavrit [(Trachurus mediterraneus (Steindachner, 1868)]’in bazı populasyon parametreleri
Authors: TORCU KOÇ Hatice , ERDOĞAN Zeliha
Published: March 2019

Bu çalışmada, Eylül 2013-Aralık 2015 yılları arasında Marmara Denizi balıkçılığında ekonomik yönden önemli olan sarıkuyruk istavrit populasyonunun boy ve ağırlık frekansları, boy-ağırlık ilişkisi, yaş ve eşey dağılımları, Von Bertalanffy büyüme eşitliği, kondisyon faktörü, gonadosomatik indeks, mortalite gibi bazı biyolojik özellikleri incelenmiştir. I – V yaş grupları arasındaki 1232 bireyin %33,87’ dişi, %% 66,13’ sı erkek olup, D:E=0.51:1 olarak bulunmuştur (p>0.05).  Boy- ağırlık ilişkisi ve büyüme eşitlikleri W = 0.044L2.470, Lt=18.6[1-e0.24(t-3.3) ]), =4.4 olarak hesaplanmıştır. Aylara göre kondüsyon faktörü değerleri incelendiğinde, ortalama en yüksek değere Haziran- ayında rastlandığı saptanmıştır.  T. mediterraneus populasyonunun üreme döneminin Temmuz ayında en yüksek değere ulaşarak, Nisan- Eylül ayları arasında olduğu belirlenmiştir.  Türün mutlak yumurta verimliliği-toplam boy F = 1.368xTL2.75 olarak tespit edilmiştir.  Toplam ölüm (Z), doğal ölüm, ve balıkçılıktan gelen ölüm oranı değerleri sırasıyla, Z= 1.36 yıl-1, M=0.33 yıl-1, F=1.03 yıl-1 olarak hesaplanmıştır. Sömürme oranı ise, E= 0.76 olup, populasyonun aşırı tüketildiği söylenebilir.
CARACTERÍSTICAS E PROPRIEDADES DO KEFIR
Authors: Sottoriva Heloysa Maria , Melo Dhara Ribeiro , Matias Taiara Cristina Fenner , Furioso Aline Aparecida , Santos Lucas Piauí dos , Alves Gilberto
Published: March 2019

Pode-se definir kefir como sendo um complexo produto lácteo fermentado produzido por fermentação do leite por bactérias ácido láticas e leveduras contidos dentro de um complexo de exopolissacarídeo e proteínas denominado de grão de kefir. Embora não seja tão popular mundialmente como outros produtos lácteos fermentados ele tem apresentado nos últimos anos um aumento de consumo devido principalmente ao seu conteúdo de bactérias probióticas e seus benefícios à saúde. O objetivo desse trabalho foi apresentar as principais características e propriedades do kefir e os benefícios de seu consumo. A composição de microrganismos nos grãos de kefir é muito variável e complexa, uma vez que depende da sua origem, condições de crescimento e manutenção, mas sabe-se que há a predominância de bactérias ácido-láticas, acéticas, leveduras e fungos. O principal polissacarídeo encontrado nos grãos de kefir é o kefirano, um heteropolissacarídeo composto por iguais proporções de glicose e galactose e que possui propriedades antitumorais, antifúngicas, antibacteriana, antiinflamatória e antioxidante. Devido a essas características, muitos produtos estão sendo desenvolvidos empregando kefir como cultura lática, como queijos, labneh, bebidas à base de extrato de soja e chás fermentados. O uso do kefir como um alimento funcional está aumentando dia a dia em todo o mundo e assim tendo um maior interesse da comunidade científica por se tratar de um alimento funcional de baixo custo, mas também várias aplicações na indústria de alimentos também estão sendo desenvolvidas.
A New Conjugate Gradient Coefficient for Unconstrained Optimization Based On Dai-Liao
Authors: Ibrahim Alaa L. , Sadiq Muhammad A. , Shareef Salah G.
Published: March 2019

This paper, proposes a new conjugate gradient method for unconstrained optimization based on Dai-Liao (DL) formula; descent condition and sufficient descent condition for our method are provided. The numerical results and comparison show that the proposed algorithm is potentially efficient when we compare with (PR) depending on number of iterations (NOI) and the number of functions evaluation (NOF).
Kardiyovasküler hastalık tanısı almış hastaların sağlıklı yaşam biçimi davranışlarının değerlendirilmesi
Authors: PERSİL ÖZKAN Özlem , BÜYÜKÜNAL Serkan Kemal , YİĞİT Zerrin , İNCİ Yusuf , ŞAKAR Fitnat Şule , ÖZÇELİK ERSÜ Dilek
Published: March 2019

Amaç: Kardiyovasküler
hastalıkların risk faktörlerini azaltmak için bireylerin sağlıklı yaşam
davranışlarını kazanmaları gerekmektedir. Bu araştırma, koroner arter hastalık
tanısı almış bireylerin sağlıklı yaşam biçimi davranışlarının belirlenmesi
amacıyla tanımlayıcı tipte kesitsel olarak yapılmıştır. Yöntem: Araştırmanın evrenini 1 Ocak– 31 Mart 2017 tarihleri
arasında, bir araştırma hastanesinin kardiyoloji polikliniklerinde takip
edilen, koroner arter hastalık tanısı almış, yaş ortalaması 57.1± 13.2 yıl
(minimum 18-maksimum 80) olan hastalar oluşturmuştur. Araştırmanın örneklemine
araştırmaya katılmayı kabul eden ve rastgele örneklem yöntemi ile seçilen 351
hasta alınmıştır. Veriler, hastaların sosyo-demografik özelliklerine ilişkin “Tanıtıcı
Bilgi Formu” ve “Sağlıklı Yaşam Biçimi Davranışları Ölçeği II” kullanılarak
toplanmıştır. Verilerin değerlendirilmesinde aritmetik ortalama, standart
sapma, minimum, maksimum ve yüzde parametreleri kullanılmıştır. Verilerin
normal dağılıma uygunluğu Kolmogorov Smirnov testiyle yapılmıştır, anlamlılık
değerleri >0.05 olduğundan ileri düzey çözümlemelerde parametrik olan
testler kullanılmıştır. Parametrik olan testlerden iki bağımsız değişken için
bağımsız örneklem t testi, ikiden fazla bağımsız değişken için One-Way ANOVA testi
kullanılmıştır. Bulgular: Araştırmadan
elde edilen bulgulara göre “Sağlıklı Yaşam Biçimi Davranışları Ölçeği II” ölçeği
toplam puan ortalaması 132.75± 3.37’dir. Cinsiyete göre ölçeğin alt
boyutlarının puan ortalamaları karşılaştırıldığında, erkeklerin manevi gelişim,
kişiler arası ilişkiler, stres yönetimi puan ortalamalarının daha yüksek,
beslenme puan ortalamasının daha düşük olduğu (p<0.05) belirlenmiştir.
Fiziksel aktivite ve manevi gelişim puan ortalamalarının yaş arttıkça azaldığı
(p<0.05), fiziksel aktivite puan ortalamasının eğitim düzeyi yükseldikçe
arttığı saptanmıştır (p<0.05). Sonuç:
Bu çalışmada, katılımcıların en düşük ve en yüksek puan ortalamalarını
aldıkları alt boyutlar sırasıyla, fiziksel aktivite ve kişiler arası
ilişkilerdir. Fiziksel aktivite alt boyutu ortalama puanının yaş ile ters,
eğitim düzeyi ile doğru orantılı olarak arttığı belirlenmiştir.
Invaginación colocólica de presentación clínica poco frecuente, secundaria a adenoma velloso malignizado.
Authors: Rodríguez Infante Antonio , Fernández Martínez Daniel , Mosteiro Díaz María Pilar
Published: March 2019

Presentamos el caso de una mujer de 76 años, sin antecedentes de interés, que ingresa por diarrea recurrente desde hace 8 meses, alteraciones hidroelectrolíticas, astenia y pérdida de peso. Colonoscopia: lesión polipoidea estenosante en ángulo hepático de colon, con carcinoma “in situ” en la biopsia.
La preparación mecánica del intestino con antibióticos orales, antes de la colectomía electiva, es la estrategia preferida para reducir las infecciones de herida quirúrgica y fuga anastomótica.
Authors: Martín Sánchez Juan Ignacio , Gómez Barbadillo José
Published: March 2019

Artículo que pone el foco en la preparación de colon previa a cirugía colorrectal. La preparación mecánica (PM) del intestino encaminada a reducir las infecciones de herida quirúrgica (IHQ) y las fugas anastomóticas (FA) sigue siendo una intervención rodeada de incertidumbre. Existen estudios que afirman que la colectomía laparoscópica electiva sin PM del colon es segura, o que no encuentran diferencias en los resultados al aplicar o no la PM del intestino. Por el contrario, hay estudios observacionales retrospectivos a partir de registros con gran volumen de pacientes que muestran que la opción más eficaz es la PM del intestino, antes de la cirugía electiva, asociado a una preparación con antibióticos orales.
Economic effectiveness of urban railway infrastructure investments in the light of globalization and regional development. Study on example of Pomeranian Metropolitan Railway construction
Authors: Miecznikowski Stanisław , Radzikowski Tomasz
Published: March 2019

The myth of a borderless world pillars of open markets – the USA and the UK – are wobbling, and China is positioning itself as globalization staunchest defender. But is a mass retreat from globalization really the right approach for companies in these uncertain times? Or short of packing up and returning home, should they focus on localization – that is producing or even innovating where they sell-as the strategy of choice? Recall that as recently as a decade ago, business leaders and politicians believed that the world and that global companies, unconstrained by countries borders, would soon dominate the world economy. Today’s turmoil calls for a more subtle reworking of multinationals’ strategies organizational structures, and approaches to societal engagement. Poland has already been a beneficent of EU funds. Actually Polish internal indebtedness is increasing and Poland will not be able to use EU funds in the future.

 

The authors would like to present the Polish issue of planning investments financed by EU funds, e.g. the project of the Pomeranian Metropolitan Railway. Construction of this railroad is the first successful project in Poland to build a new railroad since the transformation of the state system in 1989. The project was financed by the European Regional Development Fund. The decision to build the line and award the grant was made on the basis of a feasibility study. A key element of this document was the CBA analysis, which was carried out on the basis of the Blue Book for railway transport.

 

A narrow look at the economic aspects and the earlier underestimated costs of the investment caused that the investment is unfinished. The question should be asked is whether use of another method of economic analysis would help to complete this investment without the need for over a dozen years of staging investment expenditures? Difficulties with the economic efficiency account are similar to the barriers to the development of globalization.
Rational areas of combined transport technologies application for container delivery on the Caspian-Black sea route of the new Silk Road
Authors: Matsiuk Viacheslav , Vasilova Halyna
Published: March 2019

The article analyzes the main routes for delivering goods from China to the EU countries. The main transit flow in this direction is cargo in containers. The competitive Caspian-Black Sea route of the New Silk Road through Ukraine with the use of combined rail and sea transportations has been analyzed. Two delivery options are considered – using ferry ship and feeder ship lines. Simulation was used to evaluate the route parameters. Recommendations on the rational areas of combined transport technologies application on this route are given.