bluuebunny/crossref_metadata_2025 huggingface dataset:
Subthreshold Doses of Inflammatory Mediators potentiate One Another to
Elicit Reflex Cardiorespiratory Responses in Anesthetized Rats
Authors: Revand Ravindran , Singh Sanjeev K. , Muthu Madaswamy S.
Published: April 2023

Background:

Reflex cardio-vascular and respiratory (CVR) alterations evoked by intraarterial
instillation of nociceptive agents are termed vasosensory reflexes. Such responses elicited
by optimal doses of inflammatory mediators have been described in our earlier work.

Objective:

The present study was designed to evaluate the interactions between subthreshold doses
of inflammatory mediators on perivascular nociceptive afferents in urethane anesthetized rats.

Methods:

Healthy male adult rats (Charles-Foster strain) were anesthetized with an intraperitoneal
injection of urethane. After anesthesia, the right femoral artery was cannulated. Respiratory
movements, blood pressure, and electrocardiogram were recorded. The interactions between subthreshold
doses of algogens in the elicitation of vasosensory reflex responses were studied by instillation
of bradykinin (1 nM) and histamine (100 μM) into the femoral artery one after the other,
in either temporal combination in separate groups of rats. The CVR responses obtained in these
groups were then compared with the responses produced by 100 μM histamine and 1 nM bradykinin
in saline-pretreated groups, which served as control.

Results:

Subthreshold doses of histamine elicited transient tachypnoeic, hyperventilatory, hypotensive,
and bradycardiac responses, in rats pretreated with subthreshold doses of bradykinin [p <
0.01, two-sided Dunnett’s test] but not in saline pretreated groups [p > 0.05, two-sided Dunnett’s
test]. Similar responses were elicited by bradykinin after histamine pretreatment compared to the
saline-pretreated group. Furthermore, CVR responses produced by histamine in the bradykininpretreated
group were greater in magnitude as compared to bradykinin-induced responses in the
histamine-pretreated group [p < 0.05, two-sided Dunnett’s test].

Conclusion:

The present study demonstrates that both bradykinin and histamine potentiate one
another in the elicitation of vasosensory reflex responses, and bradykinin is a better potentiator
than histamine at the level of perivascular nociceptive afferents in producing reflex CVR changes.
Two Cases with 17-alpha Hydroxylase Deficiency Misdiagnosed as Primary
Aldosteronism
Authors: Akkus Gamze
Published: April 2023

Aim:

Lack of CYP17A1 prevents sex steroid biosynthesis, yielding a female phenotype in 46, XY males and sexual infantilism in both sexes; overproduction of 11-deoxycorticosterone (DOC) in the zona fasciculata typically causes mineralocorticoid hypertension. In this study, we report two cases of severe hypokalemia, hyperaldosteronism, and sexual infantilism.

Case Presentation:

Case 1 admitted severe hypertension and hypokalemia with female external genitalia with 46, XY. The patient also had right adrenal masses of 35*30 mm diameters. Case 2 was presented with delayed pubertal development with 46, XX genotype. In addition, she had severe hypertension and hypokalemia with nodular surrenal hyperplasia in her abdomen imaging.

Methods:

Further hormonal and biochemical results were followed as elevated adrenocorticotropic hormone (ACTH) levels, low serum cortisol, 17 hydroxy progesterone (17 OHP) and dehydroepiandrosterone sulphate (DHESO4) and estradiol (E2 ) levels in both cases.

Results:

Genetical analyses confirmed 17 OHP deficiency in both cases.

Conclusion:

The condition of patients with 17 alpha-hydroxylase deficiency may substantially resemble primary hyperaldosteronism and must be considered in patients as primary hypogonadism (and) associated with mineralocorticoid hypertension.
Toward Optimum Light Curing of Resin Composite Restorations: A survey on Current Awareness and Practice among General Dentists in Saudi Arabia
Authors: Haridy Rasha , Abdalla Moamen A. , Alkhalaf Rana , Albishri Rana , Alenizy Anwar Mogbel , Zeeshan Mohammad , Aldegheishem Alhanoof , AlSheikh Rasha , Elgezawi Moataz
Published: April 2023

Introduction:

This study aimed to assess the current awareness and practices of resin composite light curing of general dental practitioners (GDPs) in Saudi Arabia and to set several evidence-based recommendations to improve the quality of the outcome of concern.

Methods:

An online questionnaire was created. Two hundred and fifty email invitations were sent to GDPs appointed in general governmental hospitals in five main cities in Saudi Arabia to join the survey voluntarily and anonymously. The survey consisted of 24 questions classified into the following domains: 1-Demographic criteria 2- frequency and technical aspects of resin composites application 3- criteria of the currently used light curing units and curing light. Descriptive statistics and chi-square test were used to analyse the obtained responses.

Results:

One hundred and fifty-six responses were received. A significant number of GDPs are significantly satisfied with the quality of their light curing, not aware of the thermal hazards of light curing, and do not check power output of their LCUs (light curing units) (P<0.05). An insignificant number of respondents use eye shields for eye protection during light curing.

Conclusion:

There was no uniform light curing protocol followed by respondent GDPs. GDPs in Saudi Arabia should improve their knowledge and clinical skills of light-curing resin composite.
TRAIL and EGFR Pathways Targeting microRNAs are Predominantly Regulated in Human Diabetic Nephropathy
Authors: Rai Bhuvnesh , Pande Akshara , Tiwari Swasti
Published: April 2023

Background:

Unbiased microRNA profiling of renal tissue and urinary extracellular vesi-cles (uEVs) from diabetic nephropathy (DN) subjects may unravel novel targets with diagnostic and therapeutic potential. Here we used the miRNA profile of uEVs and renal biopsies from DN subjects available on the GEO database.

Methods:

The miR expression profiles of kidney tissue (GSE51674) and urinary exosomes (GSE48318) from DN and control subjects were obtained by GEO2R tools from Gene Expression Om-nibus (GEO) databases. Differentially expressed miRNAs in DN samples, relative to controls, were identified using a bioinformatic pipeline. Targets of miRs commonly regulated in both sample types were predicted by miRWalk, followed by functional gene enrichment analysis. Gene targets were iden-tified by MiRTarBase, TargetScan and MiRDB.

Results:

Eight miRs, including let-7c, miR-10a, miR-10b and miR-181c, were significantly regulated in kidney tissue and uEVs in DN subjects versus controls. The top 10 significant pathways targeted by these miRs included TRAIL, EGFR, Proteoglycan syndecan, VEGF and Integrin Pathway. Gene target analysis by miRwalk upon validation using ShinyGO 70 targets with significant miRNA-mRNA inter-action.

Conclusion:

In silico analysis showed that miRs targeting TRAIL and EGFR signaling are predomi-nately regulated in uEVs and renal tissue of DN subjects. After wet-lab validation, the identified miRs- target pairs may be explored for their diagnostic and/or therapeutic potential in diabetic nephropathy.
The Effect of COVID Convalescent Plasma on Hospital Stay: A
Retrospective Observational Study from a Tertiary Care Hospital
in North India
Authors: Pandey Prashant , Ranjan Shweta , Setya Divya , Kumari Supriya , Mandal Saikat
Published: April 2023

Introduction:

COVID convalescent plasma (CCP) has been used as standard of
care in patients all over the world. CCP is plasma collected from recently infected and currently
recovered COVID-19 patients, which contains antiviral antibodies that can be used to treat patients
with COVID-19. Several studies have shown a shorter hospital stay and lower mortality in
patients treated with convalescent plasma in comparison with those not treated with it.

Objectives:

This study aims to determine the effect of COVID convalescent plasma (CCP)
on the length of hospital stay in symptomatic patients and to determine outcome of the disease
in patients who were administered CCP

Methods:

This was a retrospective observational study done at a tertiary health care centre
from July 2020 to May 2021, including patients who received CCP during the course of their
stay in the hospital.

Results:

Among 257 participants, the patients with multiple comorbidities who were administered
CCP had the longest average length of stay in the hospital which was 15 days, out of
which, 92 (35.8%) patients were discharged while 9 (3.5%) patients died. Also, the maximum
number of deaths was observed in those patients who had no associated comorbidity, being 11
(4.3%). It was observed that earlier administration of CCP in patients (< 5 days from symptom
onset) was associated with a higher number of discharges as compared to deaths.

Conclusion:

Our study indicates that CCP may be efficient in treating COVID-19 patients if
given in early course of the disease.
Manajemen Perencanaan Energi Listrik Kabupaten Banjarnegara Bersumber pada PLTA Mrica Menggunakan LEAP (The Low Emissions Analysis Platform)
Authors:   Universitas Jenderal Soedirman, Ropiudin Ropiudin , Romadhon Mujihal Edo ,   Universitas Jenderal Soedirman, Priswanto Priswanto ,   Universitas Jenderal Soedirman, Kuncoro Purwoko Hari ,   Universitas Jenderal Soedirman
Published: April 2023

Perhitungan prakiraan energi dilakukan berdasarkan pada pola penggunaan energi yang sama seperti yang terjadi pada tahun dasar dan juga memperhatikan faktor perekonomian di Kabupaten Banjarnegara. Kemudian langkah selanjutnya yaitu melakukan simulasi menggunakan aplikasi LEAP untuk meramalkan permintaan energi listrik di Kabupaten Banjarnegara dan pemyediaan energi listrik oleh PLTA Mrica dengan scenario Business as Usual (BAU). Dalam melakukan skenario digunakan pendekatan trend dan ekonometri, skenario BAU mengasumsikan bahwa tidak ada intervensi kebijakan. Hasil proyeksi konsumsi energi listrik Kabupaten Banjarnegara menunjukkan rata-rata pertumbuhan konsumsi energi listrik dari tahun 2019 sampai 2031 adalah sebesar 35.16% per tahun. Proyeksi jumlah pelanggan energi listrik Kabupaten Banjarnegara menunjukkan akan adanya peningkatan dari tahun 2019 sampai dengan 2031. Proyeksi jumlah pelanggan energi listrik Kabupaten Banjarnegara yang mana menunjukkan akan adanya peningkatan dari tahun 2019 sampai dengan 2031 (selama 12 tahun) adalah sebesar 27.34%. Hasil visualisasi transformasi dan distribusi menunjukan bahwa PLTA waduk mrica masih sanggup mensuplai listrik di Kabupaten Banjarnegara hingga tahun 2031.
Diagnosis of the Question of Continuity in the Themes of Lee Yong-ak’s Poems: Focusing on Poems Written during the Wartime Period
Authors:   Korean Language & Literature, Lee Kang-Ha
Published: April 2023

This paper aims to analyze Lee Yong-ak’s poems written during the wartime period in the Japanese colonial era, raise a question about the continuity of Lee Yong-ak’s literature, and investigate the phenomenon. The thematic criterion of literary continuity assumed in this paper is Lee Yong-ak’s political stance on social reality, and the periodic category is the wartime period (1937-1945). This setting implies that some of Lee Yong-ak’s poems written during the wartime period deviated from the flow of consistency in Lee Yong-ak’s entire literature. Lee Yong-ak, who used poetry to give shape to Korean people’s suffering in the Japanese colonial era through the life history of northern immigrants, faces the wartime period’s writing situation that forces wartime mobilization and the unity of Japan and Korea. It can be summarized that Lee Yong-ak evades the subjectification mechanism of the Japanese Empire by means of three methods. The first one is a versification error in poems themselves. By writing such poems, Lee Yong-ak achieves the purpose of publishing his works in pro-Japanese media as part of his survival and at the same time sets his works free from the field of evaluation. The second one is to list both pro-Japanese content and content that denies it in one work. The so-called “included outside” subjects camouflage each other inside and outside. Censorship approves the subjects of Lee Yong-ak’s poem as tools for the wartime mobilization system, but the subjects themselves slip from the net of such a mechanism in his own strategy. The third one is the arbitrariness of the subjects of ‘Orangkaeggot (Violet)’, which were utilized in Lee Yong-ak’s own consciousness, in the political group he belonged to, and also posthumously in the criticism pursuing the continuity of Lee Yong-ak’s literature. After the liberation of Korea, Lee Yong-ak chooses the subjects who are attacked and oppressed by attackers among the various characteristics of identification that ‘Orangkaeggot (Violet)’ makes possible. With this strategy, Lee Yong-ak’s literary world, which advocates nationalism after the liberation of Korea, secures the minimum justification for taking nominally nationalistic continuity. He restores the former northern locality and strengthens the literary continuity during the liberation period and in the North Korean literary circles after going to North Korea. By literary continuity diagnosis, this paper intended to say that the duality of Lee Yong-ak’s literature should be revealed in the horizon of evaluation rather than defining Lee Yong-ak’s literature in a certain direction.
ASSESSING LOCAL GOVERNMENT PERFORMANCE TO MANAGE POVERTY ALLEVIATION PROGRAM BASED ON VALUE FOR MONEY APPROACH
Authors: Anggriawan Tommy
Published: April 2023

Various kinds of poverty reduction programs and activities have been implemented with large budget funds, but it is still difficult to see a clear justification on poverty reduction as a consequence of the policies that have been carried out. In order to increase the synergy of poverty reduction programs and to stimulate the economy of poor families, this research aims to measure the performance of the government of Pasuruan Regency by using a value for money approach based on the performance budget of a program, which uses the economy, efficiency, and effectiveness ratio. This research uses a case study research with a qualitative approach. Findings of this study indicate that the average economic ratio of the overall achievement ratio is 82.4%, it is considered economical. Overall, the efficiency ratio of the Pasuruan Regency Government's performance has been efficient, which is 134.1%,. Meanwhile, the effectiveness ratio obtained an average result of 122.41% thus it can be classified the performance of the Pasuruan Regency Government as a whole is considered effective, however, the performance of the two programs from the Health and Fisheries sector is considered ineffective. It still need a depth follow up on those programs to get a better synergy, comprehensive strategy in eradicate poverty.
POVERTY REDUCTION PUBLIC POLICY: A STUDY ON THE IMPLEMENTATION OF THE SMART INDONESIA PROGRAM IN KONAWE DISTRICT
Authors: Tadung Edy , Triawan Muh Idul
Published: April 2023

This article reviews the public policy of the Smart Indonesia Program. Qualitative research approach with descriptive method. The data were processed by in-depth interviews, observations and document review. The data were analyzed descriptively with a phenemological case study. The results of the study show that as a public policy, the Smart Indonesia program is able to alleviate poverty in the field of education for the poor with the cooperation of related parties and equalization of education for students in Konawe Regency. The implementation of the Smart Indonesia Program was analyzed in terms of the dimensions of communication, resources, disposition and bureaucratic structure. Program effectiveness needs to be determined by the program monitoring team. The school continues to proactively carry out monitoring, evaluation and guidance as well as to parents and recipient students so that the program funds used are targeted and effective in assisting student education.
TikTok and #OccupationalTherapy: Cross-sectional Study
Authors: Chasca Whitney , Nerada Samantha , Zenone Marco , Barbic Skye
Published: April 2023

Background

Medical providers use the short-form video social media platform TikTok to share information related to their scope of practice and insights about their professions. Videos under the hashtag #occupationaltherapy on TikTok have over 100 million views, but there is no evidence investigating how occupational therapy information and knowledge are shared on the platform.

Objective

The purpose of this cross-sectional study is to describe TikTok content with the hashtag #occupationaltherapy and investigate how occupational therapy is portrayed.

Methods

We performed a content analysis on the top 500 TikTok videos under the hashtag #occupationaltherapy. We analyzed occupational therapy content themes (occupational therapy intervention, education, student training, universal design, and humor), practice settings (pediatrics, generalists, dementia, hand therapy, neurology, occupational therapy students, older adults, mental health, and unknown), and sentiments (positive, negative, and neutral).

Results

The videos in our sample (n=500) received 175,862,994 views. The 2 most prevalent content areas were education (n=210) and occupational therapy interventions (n=146). The overall sentiment of the videos was positive (n=302). The most frequently observed practice settings in the videos were pediatrics (n=131) and generalists (n=129). Most videos did not state that it was occupational therapy (n=222) or misused the hashtag (n=131).

Conclusions

TikTok has the potential for occupational therapists to share innovations, build communities of practice, and engage in collaborative efforts to share information about occupational therapists’ unique roles with diverse populations. Future research is needed to monitor the quality of information and debunk inaccuracies.
Correction: Evaluation Criteria for Weight Management Apps: Validation Using a Modified Delphi Process (Preprint)
Authors: Robles Noemí , Puigdomènech Puig Elisa , Gómez-Calderón Corpus , Saigí-Rubió Francesc , Cuatrecasas Cambra Guillem , Zamora Alberto , Moharra Montse , Paluzié Guillermo , Balfegó Mariona , Carrion Carme
Published: April 2023

UNSTRUCTURED
Preventable fractions of Gastric Cancer via national screening in Asian countries 2023–40: a population-based study (Preprint)
Authors: Lin Yushi , Fang Kailu , Li Shuwen , Zheng Yang , Xiao Fenqiang , Wu Jie
Published: April 2023

BACKGROUND

The incidence of gastric cancer (GC) remains high in several Asian countries, largely due to a historical lack of national screening programs.

OBJECTIVE

As a catalyst for action, we aim to estimate the number of GC cases that could be spared in four countries in the region by 2040 if national screening interventions are introduced.

METHODS

In this population-based study, we fitted age–period–cohort models to incidence data from four Asian countries (China, Mongolia, India and Turkey) to predict the number of new GC cases between 2023 and 2040 under two scenarios. In scenario A, we assumed continued absence of national screening. In scenario B, we assumed that the implementation of GC screening starting in 2023 and the subsequent gradual impact on GC incidence would be equivalent to that observed in Korea (our comparator country) after the high-quality screening activities started in the late 2000s.

RESULTS

Under scenario A, the incidence of GC is expected to remain substantial in four Asian countries, with a high incidence of 66.1 per 100,000 in China. Under scenario B, the beneficial effects of national screening would increase gradually over time, leading to a halving of the predicted incidence in 2040, resulting in a range of prevented cases from nearly 2,600 in Mongolia to approximately 2.7 million in China.

CONCLUSIONS

In countries with a high burden of GC, intensifying screening activities for early detection of precancerous lesions may be a key intervention to promote a decrease in incidence.
aptihealth Online Multi-Dimensional Behavioral Health Screening Tool (A5): Validation Study (Preprint)
Authors: Bambury Elizabeth Ann , Ghazvini Zadeh Ebrahim , Marsal Alex G. , Carrell Katelyn Muir
Published: April 2023

BACKGROUND

1 in 5 adults in the United States experience some form of mental illness, however, most care settings use screening instruments designed for single disorders. To address this clinical gap, aptihealth has developed an online, multi-dimensional behavioral health screening tool that can accurately and reliably screen for a wide range of psychiatric disorders.

OBJECTIVE

To validate a multi-dimensional screening tool for 11 common psychiatric disorders.

METHODS

A study of reliability, content validity, and diagnostic accuracy of the aptihealth A5 was conducted. A total of 7,727 aptihealth patients who completed the A5 online between July 1st 2020, and August 31st 2022 were included. Patients complete the online screener before scheduling a diagnostic interview. At the start of care, patients receive a diagnosis from a licensed behavioral health provider, and most patients complete a Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder Scale (GAD-7). The diagnosis, PHQ-9, and GAD-7 scores are used as reference standards.

RESULTS

Of the 7,727 participants, the majority were under the age of 45 (71.8%), white (65.3%), and female (50.1%). In an expert review, the A5 items were found to have scale content validities of 87% for clarity, 98% for coherence, 96% for relevance, and 87% for sufficiency. In an alternate form reliability analysis, all A5 items demonstrated at least moderate agreement (Intraclass Correlation Coefficient of 0.40 or higher) when screeners were taken within one week of each other. The A5’s ability to accurately assess the need for treatment for depressive and anxiety disorders was demonstrated through moderate correlations with PHQ-9 (rho = 0.55, 95% CI 0.47-0.52) and GAD-7 (rho = 0.52, 95% CI 0.50-0.55) scores, respectively. Additionally, half of the disorders with a diagnosis prevalence of at least 4% had acceptable sensitivity values greater than 0.70. Finally, factor analysis reiterated the presence of 11 disorders, which were grouped into 13 symptom factors, where sleep and obsessive-compulsive disorders were comprised of two factors of symptoms.

CONCLUSIONS

These findings support the reliability and validity of the A5 screening tool to guide a diagnostic interview and provide more precise patient care.
Kejadian Carpal Tunnel Syndrome pada Pekerja dengan Gerakan Menekan dan Berulang
Authors: Nurullita Ulfa , Wahyudi Rizky , Meikawati Wulandari
Published: April 2023

Latar Belakang: Carpal Tunnel Syndrome (CTS) terjadi karena gerakan berulang yang menekan saraf median terowongan karpal, dengan gejala berupa nyeri yang berlanjut menjadi mati rasa. Pekerjaan membuka buah kapuk membutuhkan gerakan menekan dan berulang. Terdapat keluhan nyeri dan kesemutan pada sebagian pekerja dan sebagian lain mengeluhkan tremor pada tangannya. Keluhan ini sangat dirasakan saat malam hari.Tujuan: Menganalisis faktor risiko kejadian CTS pada pekerja pembuka buah kapuk.Metode: Penelitian cross-sectional ini melibatkan 34 pekerja pembuka buah kapuk. Variabel usia, jenis kelamin, masa kerja, dan riwayat arthritis reumathoid dikumpulkan melalui wawancara, status gizi dihitung berdasarkan berat badan dan tinggi badan, frekuensi gerakan berulang diobservasi. Kejadian CTS diidentifikasi melalui tes Phalen.Hasil: Umur pekerja berkisar 35‒80 tahun, mayoritas perempuan (88,2%), masa kerja 1‒8 tahun, 23,5% pekerja terdapat riwayat arthritis reumathoid, status gizi tidak normal 64,7%, 61,8% melakukan gerakan berulang, dan kejadian CTS sebesar 32,3%. Kejadian CTS berhubungan dengan masa kerja (p= 0,000), riwayat arthritis reumathoid (p=0,000), dan frekuensi gerakan berulang (p=0,001).Kesimpulan: Kejadian CTS yang cukup tinggi perlu ditindaklanjuti dengan pengendalian faktor masa kerja, riwayat arthritis reumathoid, dan frekuensi gerakan berulang.
Pengalaman Perawat dalam Melakukan Resusitasi Jantung Paru pada Pasien Covid-19
Authors: Aty Yoany Maria Vianney B. , Blasius Gadur , Herwanti Elisabeth , Selasa Pius , Gonsalves Dominggos , Nuzula Firdawsyi , Muhtar Muhtar
Published: April 2023

Latar Belakang: Tantangan perawat pada masa pandemi Covid-19 saat memberikan bantuan pasien yang mengalami henti jantung adalah penularan virus Covid-19. Perawat yang melakukan Resusitasi Jantung Paru (RJP) dengan menggunakan APD lengkap masih mungkin mengalami penularan virus yang bisa melalui droplet atau aerosol dari pasien yang terdapat di udara yang masuk melalui celah yang terbentuk tanpa sengaja oleh perawat saat bekerja.Tujuan: Mengeksplorasi pengalaman perawat dalam  melakukan RJP pada pasien Covid-19 di ruang IGD, ICU, dan ICCU RSUD Prof. W. Z Johannes Kupang.Metode: Penelitian ini adalah kualitatif dengan jenis fenomenologi. Indeepth interview dilakukan untuk menggali pengalaman perawat dalam melakukan RJP pada pasien Covid-19 yang mengalami henti jantung dan napas. Jumlah partisipan sebanyak 4 orang.Hasil: Penelitian menemukan 6 tema yakni keputusan melakukan RJP pasien, keterbatasan gerak dan mudah lelah, kesulitan memonitor kondisi pasien, cemas tertular Covid-19, rasa empati, dan kerja sama tim.Kesimpulan: Tindakan RJP pasien terkonfirmasi Covid-19 memerlukan keputusan yang tepat. Selama tindakan ini perawat mengalami kelelahan, sulit mengecek kondisi pasien karena APD yang digunakan. Perawat juga merasa takut tertular. Namun, rasa empati kepada pasien membuat perawat melakukan tindakan RJP ini dengan baik yang didukung oleh kerja sama tim yang baik.
Model Leadership Style Governor Kepulauan Riau Province During Covid-19 Pandemic in Indonesia
Authors: Kurnianingsih Fitri , Lamidi Lamidi , Adhayanto Oksep , Mahadiansar Mahadiansar , Maulana Rio Yusri
Published: April 2023

Introduction/Main Objectives: Model The leadership style of regional heads during the COVID-19 pandemic requires a compelling lead character because to deal with the problems felt by each region, and it must be different so that public responses and criticisms must be carried out quickly and accurately has a priority scale for work effectiveness. Novelty: This study analyzes the leadership style of the regional head in Indonesia, namely the Governor, by taking a case study in the Riau Islands Province (Kepri) during the COVID pandemics. Research Method: The research method used is qualitative with relevant secondary data. Finding/Results: The results of data analysis with software NVivo 12, so that obtained are easy to explain descriptively by analyzing the theory and concept triangulation approach. Conclusion: The results show that the determination of Secondary Data Coding is more on the leadership of Ansar Ahmad in the COVID-19 pandemic as Governor Kepri. In addition, researchers also found that Ansar Ahmad’s leadership style as Governor Kepri greatly influenced the characteristics of leadership style and influential leadership style, which tested with the Jaccard Cluster approach on the strong relationship between communication, awareness, and integrity in carrying out the vision and mission as regional head during a COVID-19 in Kepri Province.
Германий как материал фотоники – от линз до бездислокационных подложек
Authors: Наумов А.В. , Старцев В.В.
Published: April 2023

В статье рассмотрен процесс развития технологии роста монокристаллов германия методом Чохральского, который позволил использовать свой­ства германия для применения в ИК-оптике и в детектирование гамма-­излучения. Ожидается, что германий может вновь вернуться в оптоэлектронику: последние разработки выращивания бездислокационных кристаллов показали, что германий является перспективным материалом для наноразмерных электронных устройств следующего поколения и интеграции оптических функций на логических схемах.
АСМ-ИССЛЕДОВАНИЕ ПОСТ-ЭФФЕКТА ДВИЖЕНИЯ ГЛИЦЕРИНА В ВЫХОДНОЙ ЧАСТИ ПРОТОЧНОЙ АНАЛИТИЧЕСКОЙ СИСТЕМЫ НА АДСОРБЦИОННЫЕ СВОЙСТВА БЕЛКА
Authors: Иванов Ю.Д. , Шумов И.Д. , Козлов А.Ф. , Ершова М.О. , Валуева А.А. , Иванова И.А. , Татур В.Ю. , Лукьяница А.А. , Иванова Н.Д. , Неведрова Е.Д. , Зиборов В.С.
Published: April 2023

Методом атомно-силовой микроскопии (АСМ) исследован пост-эффект движения глицерина по спиральной проточной системе на адсорбционные свойства белка пероксидазы хрена (ПХ), инкубированного вблизи линейной части выходной части проточной системы.
СИНТЕЗ И ИССЛЕДОВАНИЕ НАНОКОМПОЗИТОВ ПЛЕНОК ОКСИДА НИКЕЛЯ И ЛИНЕЙНО-ЦЕПОЧЕЧНОГО УГЛЕРОДА
Authors: Смирнов А.В.
Published: April 2023

В работе рассмотрен эксперимент по синтезу полупроводниковых пленки оксида никеля
и композитов пленок оксида никеля с линейно-цепочечным углеродом в качестве сенсорных элементов относительной влажности. Проведены соответствующие измерения, дан анализ механизма чувствительности нанокомпозитов NiO/ЛЦУ, описывающий увеличение электропроводимости (уменьшение сопротивления) пленочных структур от влажности.
МОДЕЛИРОВАНИЕ ХИМИЧЕСКИХ РЕАКТОРОВ. КОНФИГУРАЦИЯ ЭЛЕМЕНТОВ МНОГОСТАДИЙНОГО ХИМИЧЕСКОГО РЕАКТОРА БЕСПРЕРЫВНОГО ДЕЙСТВИЯ ДЛЯ ПЕРЕМЕШИВАНИЯ ЖИДКОСТЕЙ
Authors: Баматов Д.М. , Баматов И.М. , Сапаев Х.Х.
Published: April 2023

Целью данной работы является предложение конфигурации элементов модели химического реактора беспрерывного действия, который соответствовал бы критериям идеальности работы химических реакторов. Была предложена методика для моделирования химического реактора. Семишаговая методика проектирования реакторов позволяет по заранее вычисленным параметрам подбирать материалы для реактора, проводить предварительный дизайн реактора с необходимыми массогабаритными характеристиками. Это дало возможность нам предложить конфигурацию элементов для много стадийного химического реактора для беспрерывного смешивания жидкостей. Была предложена конфигурация 6-стадийного реактора, в котором каждая стадия представляет собой изолированный объем перемешивания. Перемешивание достигается за счет колебательного элемента в виде основания реактора. Объемы перемешивания составлены таким образом, что каждый объем равняется 1 л. Все 6 объемов связаны между собой последовательно, что достигается за счет правильного дизайна крышек объема перемешивания. Также еще предусмотренным элементом конфигурации реактора является система мониторинга за температурным режимом внутри объема перемешивания реактора. Такая конструкция позволит получить многофункциональный химический реактор для беспрерывного смешивания жидкостей с производительностью до 6 л за один цикл работы.
THE POLITICAL ECONOMY OF BOLSONARO’S GOVERNMENT (2019-2022) AND LULA DA SILVA’S THIRD TERM (2023-2026)
Authors: Ferrari Filho Fernando , Bittes Terra Fábio Henrique
Published: April 2023

The article has two objectives: First, it analyses the economic policy of the Jair Bolsonaro government (2019-2022), which we define as ‘dispersed’ and ‘reactive’; second, it presents the economic challenges that Luiz Inácio Lula da Silva will face in his third term. We also speculate about proposals for possible economic policy that the Lula da Silva government should implement.
Estudio exploratorio sobre la efectividad del método abierto basado en números (ABN) en las habilidades de cálculo mental en educación primaria
Authors: Pérez Wilson Carlos , González San Martín Ivonne , Aravena Vásquez María José , Cerda-Etchepare Gamal
Published: April 2023

Se presentan los resultados del efecto que el Método ABN (Abierto Basado en Números) puede reportar en el desarrollo de la capacidad de cálculo mental en niñas y niños de primaria, comparando su efectividad con la Enseñanza Tradicional, relacionada con las prácticas habituales del profesorado y sugerida en los libros de texto. La experimentación se llevó a cabo en cursos de primer año de primaria de cuatro escuelas, dos de ellas públicas, una particular privada, y una particular subvencionada. Se diseñó y aplicó una prueba de cálculo mental de ejercicios aditivos con dos y tres sumandos, con la cual se midieron habilidades de rapidez y de precisión. Un análisis de diferencias inter-grupos evidencia la efectividad de la metodología ABN por sobre la tradicional en las mediciones realizadas. Se discuten los resultados, y sus proyecciones dentro del contexto educativo chileno
Representaciones bidimensionales de objetos tridimensionales y su relación con el desarrollo del razonamiento espacial en edades tempranas (6-8 años)
Authors: Sandoval Ivonne , Ortiz-Rocha Andrea
Published: April 2023

Relacionar un objeto y su representación en el espacio tridimensional involucra tanto acciones físicas para actuar, transformar y construir, así como procesos cognitivos de reorganización dimensional, por ejemplo, relacionar y diferenciar características propias de objetos 3D. Presentamos resultados de una trayectoria de aprendizaje en la cual, a través de la manipulación de diferentes materiales y representaciones de objetos 3D, niños de 6-8 años muestran evolución al reconocerlos, representarlos y reconstruirlos a través de diferentes vistas. En esta investigación se usó un experimento de enseñanza con 34 alumnos de una escuela pública de la Ciudad de México. Los resultados muestran evolución del razonamiento espacial respecto de: a) la integración de procesos como reconocer, representar y reconstruir; y b) cómo el movimiento influye en la percepción de relaciones espaciales. Parece factible desarrollar estrategias para transitar entre lo concreto y lo abstracto, esto es, de acciones sobre objetos a transformaciones entre representaciones.
Fanfiction en la clase de inglés como LE
Authors: Isidro Bravo Marta , García-Arroyo Ana
Published: April 2023

La enseñanza del inglés como lengua extranjera (LE) sigue aplicando métodos tradicionales, poco fructíferos, para potenciar la escritura. Por ello, este estudio se propuso como objetivos: 1) mejorar la creatividad y la escritura del alumnado de inglés como lengua extranjera, centrándose en la fluidez; y 2) motivar al alumnado para transmitir sus ideas y realidades mediante sus producciones creativas. El grupo experimental estuvo formado por estudiantes de inglés de 4º de educación secundaria obligatoria (ESO). Se utilizó la metodología de fanfiction aplicada a la escritura creativa en inglés, en la cual se parte de una obra existente para escribir sobre ésta, utilizando la imaginación. La dinámica es grupal; se aplica la teoría de la multiliteracidad y multimodalidad. Los resultados muestran cómo el alumnado publicó sus historias online, creando así “espacios afínes” y recibiendo feedback de una audiencia más extensa. Se incrementó su creatividad y su fluidez en inglés.
Evaluation of Feelings of Smart Phone Product Review Using SVM Technique of Sentiment Analysis
Authors: Parmar Priyanka , Dubey Sakshi , K Shimna Mohan. , Kadwal Mohit
Published: April 2023

Abstract: Sentiment Analysis (SA) is a task of identifying positive and negative opinions, emotion and evaluation in text available over the social networking sites and the world wide web have been gained quite a popularity in the recent years. The analysis serves as an important feedback for further improvement in the offered services and user experiences. Several techniques have been used recently including machine learning approaches and vocabulary orientated semantic algorithms. This report presents a survey of various techniques and tools have been used in the previous research sentiment analysis process. There is a massive increase in number of people who access various social networking and micro-blogging websites that gives new shapes the impression of today’s generation. Many reviews for a specific product, brand, individual, and movies etc. are helpful in directing the perception of people thus the analysts are begun to create algorithms to automate the classification of distinctive reviews on the basis of their polarities in particular : Positive, Negative and Neutral. This machine-driven classification mechanism is referred as Sentiment Analysis. The ultimate aim of this paper is to use support vector machine (SVM) classification technique to classify the feelings of good phone product review that analyses datasets used for classification of sentiments and texts.. Also, data sets are used for training as well as testing and implemented through SVM technique for finding the polarity of the ambiguous tweets. The obtain results show to achieve high accuracy as predicted on the basis of reviews of smart phone.
Evaluating the design value of the bearing capacity of steel elements designed using numerical models
Authors: Nadolski Vitali V.
Published: April 2023

Introduction. Using numerical models to analyze the behavior of complex or new structural solutions becomes increasingly popular. New software can be used by a beginner to easily create numerical models of structures, and this is, on the one hand, an undeniable advantage, which, on the other hand, raises concerns about the accuracy and reliability of the results to be obtained. It is noteworthy that the regulatory engineering framework ignores this area. Moreover, research and design communities lack any uniform approaches to modeling, and, more importantly, to interpreting results and ensuring the structural reliability of solutions.

Materials and methods. The article proposes a method for analyzing design values of the bearing capacity designated for target reliability levels, taking into account the changeability of basic variables and the modeling error. This method was developed using the Bayesian approach to quantile prediction provided that the number of validation results was limited.

Results. The article presents the implementation of the proposed method of analyzing the design value of the bearing capacity using the results of FEM (finite element method) modeling of the bearing capacity of corrugated steel beams. The influence of the assumption about the standard deviation of the modeling error is analyzed.

Conclusions. The work presents a method for determining the design values of the bearing capacity for the target levels of reliability, taking into account the changeability of basic variables and the modeling error. The factors, having a great impact on evaluating the design value of the bearing capacity and deserving further research, are substantiated. First, it is necessary to draw attention to the justification and regulation of target levels of structural reliability in regulations. Second, it is necessary to draw attention to studying statistical parameters of the modeling error and developing recommendations about the designation of apriori statistical data and maximum evaluations in respect of the standard deviation of the modeling error. Thirdly, attention must be drawn to development of criteria and formats for checking limit states in the course of design based on numerical models of the bearing capacity.
The effect of thickness of transverse and longitudinal layers on deformability and stress distribution in three-layer panels made of cross-laminated timber
Authors: Troshin Mikhail Yu. , Turkov Andrey V.
Published: April 2023

Introduction. The key feature of timber and materials, made from it, is anisotropy, or a pronounced difference between mechanical properties manifested in different directions. The construction of a cross-laminated timber plate, or a CLT panel, ensures its high strength and rigidity due to the perpendicular arrangement of fibers in mutually perpendicular layers. The article examines the effect of thickness of transverse and longitudinal layers on deformability and stress distribution in three-layer CLT panels. The relevance of the work lies in the need to obtain computational data for analyzing changes in strength characteristics of panels to select the most effective panel configuration.

Materials and methods. Due to the lack of a standardized testing methodology, SCAD+ software package was applied to conduct the studies using numerical methods. The design scheme is identified as a general system whose deformations and principal unknowns are represented by linear displacements of nodal points along the X, Y, Z axes and rotations around these axes. A three–layer plate was selected as the element to be analyzed, the outer layers of which are longitudinal, and the inner one is transverse. Its simplified design scheme is a hinged beam.

Results. The results of the study and calculations made using SCAD+ were applied to make tables and graphs showing dependence of deflection, distribution of normal and shear stresses on thickness of transverse and longitudinal layers of timber.

Conclusions. The data, obtained by the authors, allow evaluating the effect of thickness on deformability and stress distribution in three-layer CLT panels to select the effective design. A change in thickness does not always bring a large difference between mechanical properties, which allows optimizing the panel parameters. The significance of the research lies, among other things, in expanding the scientific and engineering knowledge of timber structures.
Dynamics of decline in industrial injuries
Authors: Korol’ Elena A. , Degaev Evgeniy N.
Published: April 2023

Introduction. The authors analyze the dynamics of decline in industrial injuries in 2000 to 2021. According to the Federal Service for Labor and Employment, accidents at work became more frequent in 2021 relative to 2020. In the processing industry, construction, transportation and storage sectors, the largest number of fatalities was registered in the workplace, reaching 52.2 % of the total number of all fatal accidents. The purpose of the work is to study the set of parameters, affecting

the level of industrial injuries, and to identify the factors that contribute to reducing the number of violations of labor law requirements in occupational safety.

Materials and methods. Provisions of the Labor Code of the Russian Federation and Federal Law “On Special Evaluation of Working Conditions” No. 426 dated December 28, 2013, which set the occupational safety requirements and the procedure for the special evaluation of working conditions, are the basis for verifying statistical data on industrial injuries.

Results. Unsatisfactory production and workplace arrangements were the main causes of accidents in 2021 (31 % of the total number). 16 % of accidents, that involved grave consequences, occurred through the fault of employees (violation of work performance procedures and discipline of labor — 10 %, violations of the technology process — 6 %). More than 6,000 violations of the law were revealed as a result of a special evaluation of working conditions, and the total amount of charged penalties reached 2,641,900 rubles.

Conclusions. The dynamics of decline in industrial injuries in Russia in the context of 2000–2021 has a positive trend, but it is irregular. There was a slight increase in the number of fatalities at industrial facilities in 2007, 2010 and 2021. The main reason for an increase in industrial injuries in 2021 was a ban imposed on scheduled inspections due to the coronavirus infection. To reduce industrial injuries, it is necessary to toughen penalties for violations by employers of the requirements of the labor legislation, including those regulating the special evaluation of working conditions.
Isparta İl Merkezindeki Ailelerin Beslenme Haritası ile Obezite Durum Değerlendirmesi Arasındaki İlişki
Authors: DURAN Tansu , ÖNAL Özgür
Published: April 2023

Amaç: Market rafları baz alınarak tarafımızca hazırlanan, obeziteye neden olması beklenen besinlerden oluşturulan beslenme haritası eşliğinde haneler ziyaret edilmiştir. Hanede bulunan besin miktarları, hane halkının sosyodemografik özellikleri, yeme tutumları ve fiziksel aktivite (FA) düzeyleri ile obezite ilişkisini incelemek amaçlanmıştır.
Gereç ve Yöntem: Kesitsel analitik tipte yapılan araştırma 2019-2021 bahar döneminde, çalışmaya katılmayı kabul eden hane halkına bizzat ulaşılarak yapılmıştır. Örnekleme yöntemi olarak olasılıksız örnekleme yöntemlerinden kota örnekleme yöntemi kullanılmıştır. Katılımcıların sosyo-demografik verileri (Kişisel Bilgi Formu), yeme tutumları (Yeme Tutum Testi), fiziksel aktivite değişkenleri (Uluslararası Fiziksel Aktivite Değerlendirme Anketi Kısa Formu) ve hanelerde bulunan obeziteye neden olması beklenen besinlerin gruplandırılmasıyla elde edilen beslenme haritaları ile obezite durum değerlendirilmeleri yapılmıştır.
Bulgular: Katılımcıların boy ortalaması 170,8±8,4, ağırlık ortalaması 76,0±14,2, vücut kitle indeksi(VKİ) ortalaması 26,0±4,2 ve yaş ortalaması 41,6±11,9 (min-maks=23-81) olarak tespit edilmiştir. Araştırmaya göre 10 kişiden 1‟inin evinde 2,5 litre ve fazlası gazlı içecek, 2 kişiden 1‟inin evinde hazır meyve suyu bulunmaktadır. Şekerli besin grupları incelendiğinde ise reçel %94, beyaz şeker %90 bulunma oranı ile hanelerde en çok bulunan şekerli besinlerdir. Çikolata, reçel, tatlandırıcı, şekerleme, beyaz şeker, yapay çikolata, gıda şurupları, dondurma ve kurutulmuş meyve düzeylerinin VKİ‟ ye etkisi saptanmamıştır. %91,3 oranla beyaz un, yüksek karbonhidrat içerikli besin grubundan, hanelerde en çok bulunan besindir.
Sonuç: Beslenme haritası ile obezite durum değerlendirilmesi yapıldığında kadınların erkeklere oranla obeziteye daha yatkın olduğu, artan gelir düzeyi ile obezite riskinin azaldığı, yaş ile beraber obezite riskinin arttığı ve sigara kullananların kullanmayanlara oranla daha düşük vücut kitle indeksine sahip olduğu bulunmuştur.
A atenção na cognição inventiva: entre o cuidado e o controle
Authors: Kastrup Virginia , Vieira Caliman Luciana
Published: April 2023

O livro de Virgínia Kastrup e Luciana Caliman é rico, claro e importante, a começar pelo seu título. A polaridade que estrutura o subtítulo é primeiramente política: todos os discursos voltados para as questões atencionais oscilam entre uma promessa de cuidado e vigília—benevolência, disponibilidade, preocupação—e uma ameaça de controle e vigilância—dominação, exploração, opressão. A segunda polaridade que dinamiza o título desta obra é mais discreta, mas igualmente importante. A bela expressão “cognição inventiva” é como um vulcão, tão potente quanto explosivo. Este livro traz uma riqueza de reflexões sobre os nossos próprios comportamentos atencionais e nos convida a cultivar a boa vigília, o bom cuidado, a vigília cuidadosa, o cuidado vigilante (bien-veiller): vigiar/cuidar com o outro, nos distanciando um pouco de nós mesmos através dos coletivos que formamos juntos, mas nos mantendo ligados uns nos outros por meio do nosso chão comum.
Conspiracy as ARG: media and game essence of QAnon
Authors: Algavi Leyla O. , Budtsov Gregory A. , Kovalev Georgy S. , Skvortsova Nino
Published: April 2023

The results of a comparative analysis of the functional features of the QAnon theory and the conceptual signs of ARG (games in alternative reality) are displayed. The signs of ARG are designated and given as elements of the reference game model, the basis for comparison. The authors found that the QAnon conspiracy theory, the history of its emergence and development features is of a synthetic nature: ARG elements are present in modified form. They transform the roles of developers and participants. The QAnon quest structure was visualized, the gameplay based on experiencing the state of apophenia - a painful search for a connection between random phenomena or events - was described. The similarities of QAnon with religion and at the same time political ideology based on the mechanics of the game were identified, which explains its popularity. The relevance of the topic is due to the steady growth in the number of conspiracy theories and their followers since the beginning of the Covid-19 pandemic against the backdrop of audience distrust in the media. The authors demonstrate how QAnon, not being essentially a game in an alternative reality, but using game technologies and eschatological narratives about the Great Tribulation and Judgment Day, achieves high efficiency in shaping public opinion.