bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterization of atmospheric methane release in the outer Mackenzie River Delta from biogenic and thermogenic sources
Authors: Wesley Daniel , Dallimore Scott , MacLeod Roger , Sachs Torsten , Risk David
Published: September 2022

Abstract. The Mackenzie River Delta is the second largest Arctic river delta in the world. Thin and destabilizing permafrost coupled with vast natural gas reserves at depth, high organic content soils, and a high proportion of wetlands create a unique ecosystem conducive to high rates of methane production from biogenic and thermogenic sources. Hotspots are known to have a significant contribution to summertime CH4 emissions in the region, but little research has been done to determine how often geologic or biogenic methane contributes to CH4 hotspots in the Mackenzie River Delta. In the present study, stable carbon isotope analysis was used to identify the source of CH4 at several aquatic and terrestrial sites thought to be hotspots of CH4 flux to the atmosphere. Source stable carbon isotope (δ13C-CH4) signatures were derived from keeling plots of point samples and ranged from -42 to -88 ‰ δ13C-CH4, identifying both biogenic and thermogenic and mixed biogenic/thermogenic sources. A CH4 source was determined for eight hotspots, two were thermogenic in origin, four were biogenic in origin, and two were from mixed biogenic/thermogenic sources, as evidenced by δ13C-CH4 signatures. This indicates that the largest hotspots of CH4 production in the Mackenzie River Delta are caused by a variety of sources. In addition to biogenic production at the surface we have identified CH4 migration to the surface from the Taglu gas field over an area of approximately 20 km from north to south and two different sites of mixed biogenic/thermogenic CH4 that were approximately 30 km apart.
International Monitoring System infrasound data products for atmospheric studies and civilian applications
Authors: Hupe Patrick , Ceranna Lars , Le Pichon Alexis , Matoza Robin S. , Mialle Pierrick
Published: September 2022

Abstract. The International Monitoring System (IMS) was established in the late 1990s
for verification of the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Upon
completion, 60 infrasound stations distributed over the globe will monitor
the Earth's atmosphere for low-frequency pressure waves. In this study, we
present advanced infrasound data products of the 53 currently certified IMS
infrasound stations for atmospheric studies and civilian applications. For
this purpose, 18 years of raw IMS infrasound waveform data (2003–2020) were reprocessed using the Progressive Multi-Channel Correlation (PMCC) method. A one-third octave frequency band configuration between 0.01 and 4 Hz was chosen to run this array-processing algorithm which detects coherent infrasound waves within the background noise. From the comprehensive detection lists, four products were derived for each of the certified 53 IMS infrasound stations. The four products cover different frequency ranges and are provided at the following different temporal resolutions: a very low-frequency set (0.02–0.07 Hz, 30 min; https://doi.org/10.25928/bgrseis_bblf-ifsd, Hupe et al., 2021a), two so-called microbarom frequency sets – covering both the lower (0.15–0.35 Hz, 15 min; https://doi.org/10.25928/bgrseis_mblf-ifsd, Hupe et al., 2021b) and a higher (0.45–0.65 Hz, 15 min; https://doi.org/10.25928/bgrseis_mbhf-ifsd, Hupe et al., 2021c) part – named after the dominant ambient noise of interacting ocean waves that are quasi-continuously detected at IMS stations, and observations with center frequencies of 1 to 3 Hz (5 min), called the high-frequency product (https://doi.org/10.25928/bgrseis_bbhf-ifsd, Hupe et al., 2021d). Within these frequency ranges and time windows, the dominant repetitive signal directions are summarized. Along with several detection parameters, calculated quantities for assessing the relative quality of the products are provided. The validity of the data products is demonstrated through example case studies of recent events that produced infrasound detected at IMS infrasound stations and through a global assessment and summary of the products. The four infrasound data products cover globally repeating infrasound sources such as ocean ambient noise or persistently active volcanoes, which have previously been suggested as sources for probing the winds in the middle atmosphere. Therefore, our infrasound data products open up the IMS observations also to user groups who do not have unconstrained access to IMS data or who are unfamiliar with infrasound data processing using the PMCC method. These types of data products could potentially serve as a basis for volcanic eruption early warning systems in the future.
Low-flow estimation beyond the mean – expectile loss and extreme gradient boosting for spatiotemporal low-flow prediction in Austria
Authors: Laimighofer Johannes , Melcher Michael , Laaha Gregor
Published: September 2022

Abstract. Accurate predictions of seasonal low flows are critical for a number of water management tasks that require inferences about water quality and the ecological status of water bodies. This paper proposes an extreme gradient tree boosting model (XGBoost) for predicting monthly low flow in ungauged catchments. Particular emphasis is placed on the lowest values (in the magnitude of annual low flows and below) by implementing the expectile loss function to the XGBoost model. For this purpose, we test expectile loss functions based on decreasing expectiles (from τ=0.5 to 0.01) that give increasing weight to lower values. These are compared to common loss functions such as mean and median absolute loss. Model optimization and evaluation are conducted using a nested cross-validation (CV) approach that includes recursive feature elimination (RFE) to promote parsimonious models. The methods are tested on a comprehensive dataset of 260 stream gauges in Austria, covering a wide range of low-flow regimes. Our results demonstrate that the expectile loss function can yield high prediction accuracy, but the performance drops sharply for low expectile models. With a median R2 of 0.67, the 0.5 expectile yields the best-performing model. The 0.3 and 0.2 perform slightly worse, but still outperform the common median and mean absolute loss functions. All expectile models include some stations with moderate and poor performance that can be attributed to some systematic error, while the seasonal and annual variability is well covered by the models. Results for the prediction of low extremes show an increasing performance in terms of R2 for smaller expectiles (0.01, 0.025, 0.05), though leading to the disadvantage of classifying too many extremes for each station. We found that the application of different expectiles leads to a trade-off between overall performance, prediction performance for extremes, and misclassification of extreme low-flow events. Our results show that the 0.1 or 0.2 expectiles perform best with respect to all three criteria. The resulting extreme gradient tree boosting model covers seasonal and annual variability nicely and provides a viable approach for spatiotemporal modeling of a range of hydrological variables representing average conditions and extreme events.
Multi-platform study of the extreme bloom of the barrel jellyfish Rhizostoma pulmo (Cnidaria: Scyphozoa) in the northernmost gulf of the Mediterranean Sea (Gulf of Trieste) in April 2021
Authors: Reyes Suárez Nydia Catalina , Tirelli Valentina , Ursella Laura , Ličer Matjaž , Celio Massimo , Cardin Vanessa
Published: September 2022

Abstract. On 7 April 2021, an exceptional bloom of the scyphomedusa Rhizostoma pulmo was observed in the Gulf of Trieste (Italy). Blooms of this species in the northern Adriatic Sea have been reported since the late 1800s: the density of jellyfish observed in 2021 reached more than 10 specimens per square metre. We analyse the bloom from a multi-platform approach using observations and model data at different timescales. We attempt to explain the intensity of the bloom as a consequence of thermohaline and hydrodynamical conditions in the gulf. Meteo-oceanographic conditions that may have contributed to the exceptional aggregation of jellyfish observed along the northernmost coast of the Adriatic Sea are discussed in detail. Specifically, our results indicate that this bloom was enabled by (1) the presence of a high number of jellyfish in the gulf, probably linked to the anomalously warm sea conditions in spring 2020 and winter 2021, which may have favoured a longer reproductive period and enhanced survival of adult R. pulmo, respectively; and (2) strong wind events, such as the bora wind for the Gulf of Trieste, which enhanced upwelling and mixing processes in the gulf, bringing the jellyfish from the deeper waters to the surface and clustering them along the coast.
Nuclear magnetic resonance micro-imaging of the human eye lens
Authors:   , Moffat Bradford
Published: September 2022

The exact causes of presbyopia and the development of senile cataract are still unclear. In this project magnetic resonance microscopy (MRM) has been used to study the kinetics of long-range water transport, anisotropic diffusion and refractive index distribution in the human eye lens. A decline in the transpmi process, changes to the nature of anisotropic diffusion and changes to the refractive index distribution in the lens may all be related to the onset of presbyopia and cataract. The results of the long-range water transport experiments showed that as lenses age there is reduction in the rate at which water (and presumably also water soluble low molecular weight metabolites) can enter the cells of the lens nucleus via the epithelium and cortex. Since this is the mechanism by which nuclear cells can obtain nutrients and anti-oxidants to protect the crystallins from degradation, the decrease in transport rates could lead to increased damage to lenses with age, and ultimately a potential cause of presbyopia and senile cataract. Using a modified pulsed field gradient spin echo (PFGSE) sequence, diffusion tensor maps of human lenses were acquired to study the nature of anisotropic diffusion. The nature of diffusive transport as measured by this technique was found to be related to the known morphology o the human lens. A barrier to diffusion in a region surrounding the lens nuclei was observed. Changes to the permeability of this barrier with age were also found to be significant. This may be partly responsible for degeneration of lens function and contribute to presbyopia and senile cataract. A Carr-Purcell-Meiboom-Gill (CPMG) pulse sequence was used to study the nature of transverse relaxation in lenses and lens homogenates. The rate of this relaxation (R2) was found to be linearly related to the refractive index. The refractive index distribution in intact human lenses was then acquired by obtaining spatial image maps of R2 using a modified CPMG imaging sequence. The results ofthese measurements show subtle but potentially important differences in refractive index distribution from those currently used in models of the lens refractive index gradient. The results also provide new insight into changes in the refractive index distribution with aging. These changes may contribute to presbyopia and help to explain the "lens paradox".
Phytochemical screening and Invitro Anticancer activity of Lonicera ligustrina leaf extract on Breast and Colorectal carcinoma cell lines
Authors: Chandra Murthy Chaganti Sai Sri Rama , Kumar Sanapala Arun , Sambamoorthy Unnam , Paul babu Kasireddy , Sunkara Namratha
Published: September 2022

Cancer can be described as a disease characterized by groups of aberrant cells that undergo uncontrolled proliferations in the absence of cell cycle regulation. The metastasize cancer cells spread to various locations in the body where their uncontrolled growth invades the normal tissue. Cancer comprises more than hundred different diseases, including malignant tumors of different sites such as breast, cervix, stomach, intestines, colon, lung, mouth etc. There are numerous factors responsible for the cause, like genetic, tobacco, chemicals, environmental factors, hormones etc. Cancer detection is described by their pathological grade and clinical stage. Thus we have made an attempt to use Lonicera ligustrina herbal extract to check the efficacy against breast and colorectal carcinoma cell lines. The present study aimed to evaluate preliminary phytochemical screening and invitro anticancer potential activities against MCF-7(breast) and HCT-116 (colorectal) cancer cell lines. Samples shown significant activity at its higher concentration and the IC50 value of breast cell lines 24.45µM (MCF-7) and colorectal cell lines 9.210µM (HCT-116) inhibition. Standard Doxorubicin tested against MCF-7 and HCT-116 cell lines showed IC50 value of 18.76µM and 16.89µM inhibition. Therefore, a dynamic view of IC50 values and the methods used to detect the density-dependent IC50 spectrum of a cancer cell line (primary or passaged) established. This view will benefit patients and the cancer research community as a whole.
The Role of Liver Function Tests in Monitoring the effect of Enzyme Replacement Therapy in Children with Gaucher Disease
Authors: A. Abdulamir Haidar , A A Aldafaay Ameer , Al-Shammari Ahmed Hamza
Published: September 2022

Background: Gaucher disease (GD) is an autosomal recessive hereditary disease. The etiology, pathophysiology, diagnosis, and prognosis of GD in children might all be affected by a variety of biomarkers. The majority of them are linked to abnormalities caused by this lysosomal storage disorder, which is caused by a deficiency of the glucocerebrosidase enzyme that affects numerous organs including the liver, spleen, and bones. Objectives: to investigate the relevance of liver function tests in the assessment of treatment response in children with Gaucher's disease who are undergoing enzyme replacement therapy in a follow-up manner. Methods: A case-control study was performed on 67 children (girls and boys) with GD who were recruited from the Children Welfare Hospital Consultation Clinic, the Gastroenterology and Hepatology Teaching Hospital, and the Central Child's Teaching Hospital. The levels of ALT, AST, total bilirubin (TB), and total protein (TP) were assessed in the samples of 67 Gaucher children, who were classified as recently diagnosed untreated patients (n=9), patients who received ERT for 3-6 months (n=18), 6-12 months (n=20), and patients who received ERT for more than one year (n=20), and compared to twenty newly comparable age-matched controls. The practical part of the study was conducted at research laboratories in the College of Pharmacy, Al-Maaql University and the Department of Pharmacy, Al-Turath University College during the period from December 2020 to March 2021. Results: The results showed that total protein levels in patients were significantly lower than in age-matched control group. The negative significant correlations between the levels of AST, ALT, and TB with the period of receiving treatment and the positive significant correlations between the levels of total protein and the period of receiving treatment indicated that the studied parameters were significantly associated with the period of receiving ERT. The effect of ERT was also indicated by the results of the ANOVA test, which revealed significant variations in the levels of ALT, AST, total bilirubin, and total protein across the patient subgroups. Conclusions: ALT, AST, total bilirubin, and total protein have been shown to have diagnostic significance in newly diagnosed untreated children with a wide range of treatment responses, limiting their utility in treatment monitoring.
Atorvastatin induced liver injury: A Case Series
Authors: Sreenivasan Anjana , KS Lekshmipriya , Vijayan Meenu , G Pai Praveen
Published: September 2022

Atorvastatin is the most widely used statin for the prevention and treatment of cardiovascular disease. It belongs to the class of drugs called HMG-CoA reductase inhibitors. One of the most significant side effects of statins is liver injury. Liver injury as evidenced by elevation in liver enzymes occurs in some patients treated with atorvastatin 10mg to 80mg. Therefore, Liver function tests (LFTs) need to be assessed before initiating atorvastatin therapy and to be repeated thereafter. Here we discuss three cases of liver enzyme elevations within 24hrs of atorvastatin treatment. Liver enzymes were completely returned to baseline after discontinuing the therapy. The risk factors of atorvastatin induced liver injury are increased age, chronic diseases, and coadministration of drugs metabolised by Cytochrome P450 3A (CYP3A) enzyme.
The Distribution of ABO blood groups among type 2 Diabetes mellitus patients with or without Chronic Microvascular Complications
Authors: Jaafar Mohammed Sarah , S. Amin Seenaa
Published: September 2022

The ABO blood group system is highly polymorphic, with more than 20 distinct sub-groups; study findings are usually related to ABO phenotype, but rarely to the ABO genotype and animal models are unsatisfactory because their antigen glycosylation structure is different from humans. Both the ABO and Rh blood group systems have been associated with a number of diseases, but this is more likely related to the presence or absence of these tissue antigens throughout the body and not directly or primarily related to their presence on RBCs. A total of fifty-two 52 patients without complication of DMII, two hundred sixteen 216 patients with complication of DMII and seventy-one 71 person as healthy control were included in the study. The results of the study showed a significant difference in distribution of ABO blood groups between (healthy and DM II subjects) and between (DM II with complication and DM II without complication group), the comparison in the distribution of ABO blood groups among diabetic nephropathy, diabetic retinopathy and diabetic neuropathy groups shows non- significant difference.
Sorafenib Induced Oxidative Stress in Testicular Tissue of Male Swiss Albino Mice
Authors: D. Shetty Surekha , Bairy K. Laxminarayana , Aithal P. Ashwini
Published: September 2022

Objective: Male gonadal toxicity is a common complication of modern anti-cancer treatments. Oxidative stress can lead to damage to the structure of testis and germ cells. Oxidative stress develops in association with an imbalance between reactive oxygen radicals and the antioxidant reserve system. Antioxidants are compound that protect cell against the damaging effects of reactive oxygen species. The aim of this study was to investigate the effect of sorafenib on antioxidative enzyme superoxide dismutase in testicular tissue of male Swiss albino mice. Materials and Methods: The animals were segregated into control, positive control, and treatment groups (n=6 in each group). Treatment group received 25, 50 and 100mg/kg body weight of sorafenib orally for seven consecutive days at intervals of 24 hours between two administrations. Positive control group received 100 mg/kg body weight of imatinib. The animals were sacrificed at the end of 1st, 2nd, 4th, 5th, 7th and 10th week after the last exposure to sorafenib. The testis were removed, weighed, and processed for superoxide dismutase activity assay. Results: The superoxide dismutase activity was reduced significantly (P<0.05) during the 1st, 2nd, 4th, 5th and 7th week sampling time in mice treated with all the doses of sorafenib. Superoxide dismutase activity returned closer to control group in 10th week sampling time. Conclusion: The administration of sorafenib decreases the superoxide dismutase activity in testicular tissue. It lead to imbalance between antioxidant system and reactive oxygen species generation, which produced the oxidative stress.
Groundwater exploitation in Mexico: the situation is getting worse
Authors: Cordova Cuauhtemoc Osorno
Published: September 2022

In Mexico, the serious problem of groundwater overexploitation is not slowing down, nor are there signs that the situation is going to improve. Of the existing 653 aquifers in the country, 157 were registered as overexploited as of 2020. This number has increased for years, demonstrating the resounding failure of water governance from all federal governments. This trend is characterised by poor political will on the matter, invisibilisation of the problem, corruption in management, an absence of comprehensive long-term projects, and weak governance - among other causes which are discussed in the policy brief. Factors such as unsustainable economic and urban growth, severe surface water pollution, and a lack of budgetary and regulatory reforms complicate the country’s outlook further. It is necessary to continue analysing the problem and to generate momentum to boost public policies and promote sustainable development for greater water security in Mexico.
醫事人員之病人安全文化對工作生活平衡之影響—復原力之調節效果
Authors: 黃婕羚 黃婕羚
Published: September 2022

目的：工作與生活像是天秤的兩端，當一端壓力過大，就會失去平衡。當醫事人員無法兼顧工作、家庭與個人生活，將無法專注投入工作，影響其工作表現及生產力，恐對於病人照護產生負面衝擊。

研究方法：本研究採用問卷調查法，運用財團法人醫院評鑑暨醫療品質策進會發展之新版病人安全態度問卷(New-Safety Attitudes Questionnaire, New-SAQ)進行調查，並以階層迴歸分析(Hierarchical Regression)驗證本研究假設。

研究結果：病人安全文化與復原力之交互作用項對於工作生活平衡不具有顯著影響，比較主要效果，「復原力」對於工作生活平衡具有顯著正向影響。

結論與建議：醫事人員病人安全文化與復原力之平均分數不互相影響，但均對於工作生活平衡有顯著影響，尤其是復原力之影響甚鉅，具有高度顯著之正向影響。建議醫院可深入研究「復原力」專題，由「關懷」著手，提供工作上的支持，以培養醫事人員之職場復原力及韌性，並著重於教導問題解決能力、正念認知及壓力處理等，以避免導致工作生活失衡，而影響醫療品質及病人安全。

 

Objectives: Work–life balance is associated with productivity and work performance, and among health care workers, poor work performance can be detrimental to patient safety.

Methods: This study used the new version of the Safety Attitudes Questionnaire (NEW-SAQ) developed by Joint Commission of Taiwan. Hierarchical regression was used to verify the research hypothesis.

Results: The interaction between patient safety culture and resilience had no significant effect on work–life balance, whereas resilience had a significant positive effect on work–life balance.

Conclusion: The average scores of patient safety culture and resilience did not affect each other but had significant effects on work–life balance. In particular, resilience had a highly significant positive effect. Hospitals should encourage health care workers to improve their resilience, problem-solving skills, stress management skills, and mindfulness, because doing so improves work–life balance and thus patient safety.

 
Rezension von: Engl, Richard, Die verdrängte Kultur
Authors: Reichert Folker , Engl Richard
Published: September 2022

Richard Engl, Die verdrängte Kultur. Muslime im Süditalien der Staufer und Anjou (12. – 13. Jahrhundert) (Mittelalter-Forschungen, Bd. 59). Ostfildern: Jan Thorbecke 2020. 380 S., 45 Abb. ISBN 978-3-7995-4379-8. € 50,–
Rezension von: Schmidt, Rainer F., Kaiserdämmerung
Authors: Fritz Gerhard , Schmidt Rainer F.
Published: September 2022

Rainer F. Schmidt, Kaiserdämmerung – Berlin, London, Paris, St. Petersburg und der Weg in den Untergang. Stuttgart: Klett-Cotta 2021. 878 S., 17 s/w Abb. ISBN 978-3-608-11683-0. Geb. € 38,–
Rezension von: Strothmann, Jürgen, Karolingische Staatlichkeit
Authors: Eberl Immo , Strothmann Jürgen
Published: September 2022

Jürgen Strothmann, Karolingische Staatlichkeit. Das karolingische Frankenreich als Verband der Verbände (Ergänzungsbände zum Reallexikon der Germanischen Altertumskunde, Bd. 116). Berlin: de Gruyter 2019. XII/506 S. ISBN 978-3-1106-4120-2. Ln., Geb. € 119,95
Rezension von: Thali, Johanna; Palmer, Nigel F. (Hrsg.), Raum und Medium
Authors: Kirakosian Racha , Thali Johanna , Palmer Nigel F.
Published: September 2022

Raum und Medium. Literatur und Kultur in Basel in Spätmittelalter und Früher Neuzeit, hg. von Johanna Thali und Nigel F. Palmer (Kulturtopographie des alemannischen Raums, Bd. 9). Berlin: de Gruyter 2020. 584 S., 40 Abb., 23 Farbabb. ISBN 978-3-1105-3141-1. Geb. € 99,95
Rezension von: Bickhoff, Nicole; Mährle, Wolfgang (Hrsg.), Romantik in Württemberg
Authors: Clemens Gabriele B. , Bickhoff Nicole , Mährle Wolfgang
Published: September 2022

Nicole Bickhoff / Wolfgang Mährle (Hg.), Romantik in Württemberg (Geschichte Württembergs, Impulse der Forschung, Bd. 6). Stuttgart: Kohlhammer 2020. 254 S. ISBN 978-3-17-039340-0. € 28,–
Rezension von: Kropp, Claus; Becue, Tatiana (Red.), Das Mittelalterliche Hausschwein
Authors: Fritz Gerhard , Kropp Claus , Becue Tatiana
Published: September 2022

Claus Kropp / Tatiana Becue (Red.), Das Mittelalterliche Hausschwein. Forschungsstand, Perspektiven, Potenzial (Laureshamensia. Forschungsberichte des Freilichtlabors Lauresham, Sonderausgabe 1/2020). Bad Homburg v. d. Höhe: Staatliche Schlösser und Gärten Hessen, UNESCO Welterbe Kloster Lorsch 2020. 110 S. ISBN 978-3-96184-020-5. € 7,50
La paradoja de la redistribución en el Chile actual
Authors: Maldonado Luis , Canales Andrea
Published: September 2022

Sobre la base de la teoría de la paradoja de la redistribución de Korpi y Palme (1998), este trabajo presenta una reflexión sobre la construcción de un régimen de bienestar universal en Chile actual. Argumentamos que la situación nacional actual ilustra un nuevo tipo de paradoja de las políticas sociales llamada de la no-complementariedad, que implica un desajuste entre las dimensiones que importan para la pobreza y las que son relevantes para las preferencias redistributivas. A partir de una serie de análisis estadísticos de fuentes secundarias, se muestra evidencia a favor de este desajuste. Concluimos con reflexiones e implicancias para el desarrollo del universalismo en la sociedad chilena.
Avaliação da capacidade de indução de calos embriogênicos em óvulos abortados de citros
Authors: Santos Karen Cristina Fialho dos , Cardoso Maria Gerolina Silva , Souza Antônio da Silva , Verde Denise dos Santos Vila , Pinto Camila Rodrigues
Published: September 2022

O cultivo de óvulos abortados se constitui uma das formas para obtenção de calos embriogênicos, que, por sua vez, incide em uma via para a obtenção de indivíduos haploides em citros. Assim, o objetivo desse trabalho foi estimular a formação de calos embriogênicos mediante o cultivo in vitro de óvulos abortados de genótipos de citros. Para isso, foram coletados frutos das laranjeiras ‘Azeda’ clone Jacarandá e ‘Hamlin’ clone CNPMF 04, do limoeiro ‘Cravo’ clone Santa Cruz e das tangerineiras ‘Sunki Maravilha’, ‘Sunki Tropical’ e ‘Cleópatra’ para extração dos óvulos abortados, que foram desinfestados em câmara de fluxo laminar e introduzidos no meio de cultura MT suplementado com 50 g L-1 de sacarose e 500 mg L-1 de extrato de malte e posteriormente mantidos no escuro a 27±1ºC. Obteve-se formação de calos embriogênicos em todos os genótipos estudados, em taxas que variaram de 7% a 54,5%, na tangerineira ‘Sunki Tropical’ e na laranjeira ‘Azeda’ clone Jacarandá, respectivamente. Diante disso, ainda são necessários ajustes no meio de cultura, a fim de aumentar os percentuais de calogênese, contudo os calos obtidos já podem ser utilizados para a etapa de regeneração in vitro.
Caracterização da dieta em adultos de meia idade e idosos com diabetes mellitus atendidos pela atenção primária à saúde
Authors: Niehues Daniele Cristina Fernandes , Hatisuka Marla Fabiula de Barros , Girotto Edmarlon , Vagula Julianna Matias , Cabrera Marcos Aparecido Sarria
Published: September 2022

Objetivo: Analisar o padrão da dieta de indivíduos adultos de meia idade e idosos com diabetes mellitus atendidos em atenção primária à saúde. Métodos: Estudo transversal com amostra composta por 200 indivíduos com diabetes mellitus com 45 anos ou mais e em uso medicamentos antidiabéticos, de duas unidades de saúde de um município de grande porte do Paraná, Brasil. Foram levantadas informações sobre características sociodemográficas, estilo de vida, preparação da alimentação e padrão alimentar. Resultados: Verificou-se que 62,5% não sabiam informar possíveis facilitadores para a adesão à dieta. Entre os alimentos de baixo índice glicêmico, o maior consumo foi de arroz integral/polido (86,0%) e feijão (71,0%). Já dentre os alimentos com médio ou alto índice glicêmico, foram mais relatados o pão francês/forma/doce ou torrada (75,5%), mel/açúcar (42,0%) e café/chá com açúcar (40,5%). Conclusão: Há uma alta prevalência na ingestão de alimentos com alto índice glicêmico pelos entrevistados. Estratégias para promoção de alimentação saudável devem ser realizadas a fim de promover mudanças no comportamento alimentar.
Educação na pandemia: relatos de experiências dos estudantes de nível superior
Authors: Barbosa Andre Machado , Batista Regina Lucia Napolitano Felicio Felix , Viegas Marco Antonio Serra , Costa Marco Aurelio Carvalho da
Published: September 2022

O propósito da pesquisa foi ouvirmos estudantes do ensino superior sobre suas experiências com o novo modelo de aula proposto pelas IES (Instituições de Ensino Superior). Buscou-se saber e analisar o processo de ensino/aprendizagem e sobre o grau satisfação   a respeito do novo modelo de aulas. A pesquisa é quali-quanti pela necessidade, também, de tabularmos os percentuais, dada relevância do estudo. Dentre os resultados, enfatizamos as repostas sobre o impacto do distanciamento social na própria aprendizagem, quase metade (41,3,%)  dos estudantes responderam  que o impacto foi forte. Além disso, os outros resultados demonstram algum tipo de problema nesse processo por parte de muitos discentes, atinentes ao exame dessa pesquisa.
Alfabetização científica: representações sociais sobre iniciação científica de professores PDE-PR em Química
Authors: Nóbrega Danielly , Crevonis Galego João Pedro , Henrique Samuel Cândido Henrique , Linhares Clarice  Schneider Linhares
Published: September 2022

O objetivo do presente estudo é realizar uma pesquisa do tipo “Estado da Arte” dos artigos científicos da área Química, produzidos por professores que promoviam Alfabetização Científica no Paraná. Os artigos foram realizados como parte do processo de formação continuada do Programa de Desenvolvimento Educacional do Paraná (PDE-PR). Essa produção está disponibilizada em Cadernos PDE-PR, turmas 2007 a 2016. A opção por identificar e sistematizar os resumos contidos em oito Cadernos PDE-PR, com leitura na íntegra dos artigos, visou selecionar e categoriza aqueles que contemplavam práticas que promoviam a Alfabetização Científica. Depois de sistematizados por modelos REDUC e configurado o Corpus, processaram-se os dados no software (IRAMUTEQ), o que possibilitou as análises de similitude e nuvem de palavras. A análise, com o aporte teórico da Teoria das Representações Sociais, indica que as produções apresentam alguns indícios sobre a Iniciação Científica na Educação Básica, os quais apontam para a Alfabetização Científica, além de evidenciar a baixa formação dos professores para práticas de Iniciação Científica, a precariedade dos laboratórios e a falta de uma Política Pública do estado do Paraná.
O julgamento de processos por inteligência artificial analisado à luz dos Princípios de Bangalore de Conduta Judicial
Authors: De Oliveira Pedro Enrico
Published: September 2022

A inteligência artificial é realidade no julgamento de processos e se verificou a necessidade de relacionar os possíveis reflexos desta ferramenta na conduta judicial. O estudo teve o propósito de verificar se os Princípios de Bangalore de Conduta Judicial são compatíveis com o uso de modelo preditivo de inteligência artificial para julgar o processo judicial. Tratou-se de pesquisa multidisciplinar desenvolvida por meio de revisão bibliográfica, realizando-se a análise das informações pelo método qualitativo. O resultado obtido é de que não há incompatibilidade entre o padrão de conduta judicial estabelecido pelos Princípios de Bangalore e o uso de modelos preditivos de inteligência artificial para julgar o processo judicial, todavia, foram identificadas ameaças para a conduta judicial e, então, foram sugeridas medidas que a salvaguardem.
grammatical controversy on accusative nouns
Authors: Sa'ib Saleh Sumayah , Abid Zaidoun Fadhel
Published: September 2022

This research paper aims at recognizing the study of a set of the accusative nouns and the controversy among scholars on them in one of Arabic Language books which is (Al-Azhar Shareh Edhehar Al-Asrar in Grammar) for Ibrahaim Al-Kassab Al-Roomy Al-Hanafi (deceased 1029 H.) for its importance upon the researchers, where they engaged on studying the explanations that carried out on this book and to pay attention to what included of valuable scientific material. I chose to make my study in the section of the Accusative Nouns and what contained of a grammatical controversy among the grammarians that the book clarified.
Phenotypic and molecular diagnosis using polymerase chain reaction (PCR) technology for some aflatoxin-producing fungi isolated from food
Authors: AL-Tamimi Muna J. N. , AL-Zobaidy Ban M. H.
Published: September 2022

The study was conducted in the laboratories of the College of Education for Pure Sciences for the academic year 2021-2022 on fungi that produce aflatoxin toxin that were isolated from some foodstuffs traded in the local markets in the city of Karbala and were diagnosed molecularly using a technique Polymerase chain reaction (PCR) which successfully doubled NS8 and NS1 with prefixes (SSU-) The same primers were used to determine the sequence of nitrogenous bases of rRNA belonging to the International Center for Information Technology Genbank. National Center of Biotechnology Information (NCBI) it has been deposited in a database (fungi biogenic). The results of isolation, which were collected from imported and local foodstuffs, were contaminated with fungi, and that all isolated fungi were producing aflatoxin toxin. This was inferred by using coconut medium with ammonia solution. hf ifheehehai eifenhihehidnhf eht dna Penicillium oxalicum, Penicillium expansum, Aspergillus flavus, Cladosporium Uredinicola, Aspergillus sydowii, Aspergillus Oryzae, Aspergillus Tamarii, Aspergillus nomius, Alternaria triticina, Penicillium griseofulvum, Aspergillus austwicki, Aspergillus flavus, Cladosporium cladosporioides, Actinomucor elegans, Penicillium brevicompatum, Trichophyton mentagrophytes, Gibberella intermedia, Debaryomyces hansenii, Aspergillus caespitosus, Aspergillus versicolor.
Study of some histological effects of the preservative sodium nitrite in the fetuses and pregnant rat females
Authors: AL-Rubaie Zainab Majed Mohamad , AL–Essawi Dalal Abdel-Hussein Kadhem
Published: September 2022

This study was carried out in the animal house of the College of Science at the University of Kufa from 15/11/2021 to 15/5/2022for the purpose of studying the harmful histological effects of the preservative sodium nitrite in some organs (livers, kidneys and brains) of fetuses during gestation (16,20 days) and during the three stages of gestation (7,16,20) days respectively  of  pregnant female rats that were treated with sodium nitrite,45 pregnant rat female of Rattns rattus type (Sprague Dawley) whose averages weights were (230) g and ages were (12) weeks, pregnant rats were divided into 3 main groups and each group contained 15 pregnant females: the first group was treated with physiological salt solution and was as a control group, while the second group was dosed sodium nitrite at a concentration of 10 mg/kg of body weight, while the third group was dosed sodium nitrite at a concentration of 15 mg/kg of body weight, each of the main groups was divided into 3 secondary groups, each of which included 5 pregnant rats, the first, second and third secondary groups from each main groups were dissected during (7,16,20) days of gestation, respectively,,,,
Bacteriological, molecular and histopathological evaluation of four vaccines’ protective role against caseous lymphadenitis in sheep
Authors: Syame Sohier M. , Abuelhag Hussein A. , Kandil Mai M. , Gaber E. S. , Ebessy Eman A.
Published: September 2022

The caseous lymphadenitis disease (CLA) due to Corynebacteriumpseudotuberculosis has worldwide distribution and indicates high prevalence in different countries. The bacterium has many pathogenicity factors; firstly, “phospholipase D”, an exotoxin virulence factor that enhances vascular permeability and facilitates bacterial transmission causing endothelial cell damage. The bacterium's exterior lipid cover is the second pathogenicity factor. This protects it from hydrolytic enzymes found in the phagocytes of the host, where the bacteria proliferate and then release after rupturing.  Bacterial proliferation causes CLA abscesses, which are followed by attraction and the formation of an inflammatory response, which increases lymph flow and vascular permeability. The purpose of this study was to look atpostmortem findings, bacterial cultures, and histology of vaccinated sheep to see how well they were protected. On 15 male local sheep bread, four prepared vaccinations against C. pseudotuberculosis biotype 1 were tested. The animals were divided into 5 groups; four of various vaccines used and the fifthwere kept non-vaccinated. A live virulent strain of C. pseudotuberculosis was given to each group. Unvaccinated animals displayed CLA symptoms similar to those seen in spontaneously sick animals.
Antigenic evaluation of extracted fimbrial protein obtained from pathogenic Escherichia coli isolated from diarrheic camel neonates
Authors: Dapgh Amany N. , Shahein Momtaz A. , Kamel Essam , Ali Samah F. , Ragab Aml M. , Hakim Ashraf S. , Khairy Eman A. , Abuelhag Hussein A. , Fouad Ehab A.
Published: September 2022

Enteropathogenic Escherichia coli (EPEC) were considered prime reason of diarrhea among neonatal livestock animals in developing countries and could be of public health importance via contaminated milk and meat.  Continual attempts were conducted to combat this illness using various antigenic determinants. This study was performed on four E. coli serotypes O26, O45, O103 and O111, which were previously recovered from diarrheic camel calves in Giza, Egypt. Extraction of fimbrial proteins was carried out through dialysis then evaluation of their immunogenic activity was preceded. SDS-PAGE electrophoresis was performed on crude extracted fimbrial proteins and revealed single band for each isolate ranged from 22 to 33kDa. Immunobloting was implemented on the extracted crude fimbrial proteins against E.coli O26 antisera formerly prepared in rabbit.These findings suggested that the fimbrial proteins are of immunogenicity importance and can serve as a protective passive vaccine antigen in prevention of diarrhea caused by EPEC and ETEC infection in camel calves.
Essential oil composition and biological activities of Hyssopus officinalis and Perilla frutescens
Authors: Eldeghedy Hanem I. , El-Gendy Abd El-Nasser G. , Nassrallah Amr A. , Aboul-Enein Ahmed M. , Omer Elsayed A.
Published: September 2022

This article reports on the main constituents of Hyssopus officinalis and Perilla frutescens essential oils (EOs) and their activity as antioxidant, antimicrobial, anti inflammatory and anticancer. The major component of H. officinalis essential oil was isopinocamphone followed by pinocamphone, β-pinene, β-phellandrene, α-thujene and bicyclo-germacrene. The main constituent of the essential oil of P. frutescens was identified as L-perillaldehyde followed by trans-caryophyllene and D-limonene. Both essential oils (hyssop and perilla) showed antioxidant activities with the used three methods and the increase of activity was concentration dependent up to 32μg/ml comparing to ascorbic acid.  The values of IC50 for DPPH radical scavenging were in the order of P. frutescens< ascorbic acid< H. officinalis. The values of IC50 for FIC method were in the order of ascorbic acid< P. frutescens< H. officinalis. The IC50 for ABTS method was 8μg for P. frutescence and the values were in the order as ascorbic acid< H. officinalis< P. frutescence. The essential oil of both plant species showed variable activities against all the tested bacterial. The results displayed also that the essential oil of P. frutescens showed significant fungal inhibitions against the four tested Candida strains.
Impact on ruminant performance of feed additives
Authors: Mohammad Sundos Farook
Published: September 2022

In order to elicit the desired reaction at animals, feed additives must be included in high concentrations in the diet. Microorganism-based feed additives for ruminants have been more popular over the last two decades, and this trend is expected to continue. Dairy farmers may utilize feed additives to enhance the nutritional content of their dairy cows' meals and boost revenues by using them properly. The use of supplements should not be seen as a substitute for well-balanced diets and sound feeding procedures, but rather as an addition to them. Although yeast biomass, a byproduct of the alcoholic beverage industry, has previously been employed as a protein source, research into feeding yeast as a probiotic began in the 1950s. Probiotics like yeast were only employed as a feed additive at a lesser level. It was in the 1940s and 1950s when Saccharomyces cerevisiae (Sc) was first used as a probiotic in tiny doses added to animal feed. Anaerobic cellulitis bacteria count and ruminal PH value may be improved by adding yeast to ruminant diets, according to research. mineral absorption is influenced by the patterns of volatile fatty acids.
Clinical contemplation and management of multiple impacted canines
Authors: Ahuja Gaurav , Waingkar Akshay M. , Singla Marry , Singh Shikha , Dhurubatha J. , Wadhawan Ashutosh
Published: September 2022

The impaction of the maxillary canines causes relevant a esthetic and functional problems. The multidisciplinary approach to the proper planning and execution of orthodontic traction of the element in question is essential. Many strategies are cited in the literature among the mis the good biomechanical control in order to avoid possible side effects. The aim of this paper is to present a case report in which a superior canines impacted by palatine was pulled out with the aid of direct traction with the help of elastics and arch wires. A 19-year-old male patient reported with a chief complaint of malaligned teeth and missing some teeth. The proposed treatment prioritized the traction of the upper right canine without changing the occlusion and aesthetics. For this, straight wire appliance with .022 slot was inserted in order to minimize unwanted side effects. The use of cantilever to the traction of the upper right canine has enabled an efficient and predictable outcome, because it is of statically determined mechanics. Comprehensive orthodontic therapy along with surgical exposure of 13, 33 and 43 helped in achieving all the treatment objectives to great satisfaction without any adverse effects on the periodontium or the dentition.
Determine the effect of the lipid peroxidation end product (4-Hydroxynonenal) in the context of atherogenic among COVID-19 cases
Authors: Ahmed Banaz S. , Hameed Rana M. , Hussei Radhwan M.
Published: September 2022

Background: Coronavirus disease 2019 (COVID-19) manifests as multiple clinical and pathological organ dysfunctions. It also disrupts metabolic profile due to the release of pro-inflammatory cytokines causing a systemic inflammation reaction. As the number of COVID-19 complications continues to rise worldwide, the identification of risk factors for the disease is an urgent issue, and it remains controversial whether atherogenic lipid-related traits including lipid peroxidation product 4-Hydroxynonenal and lipid profile panel levels, are risk factors. The aim of this study was to estimate causal effects of lipid-related factors on COVID-19 risk Methods: This case control study includes (90) subjects, were divided into: (30) critical, (30) sever COVID-19 groups, and (30) control group. Samples of COVID-19 patients were collected from Al-Hayat unit at Imam Hussein Medical City/ Iraq. This study was included all patients that confirmed with positive RT-PCR in the hospital, and only smoked patients were excluded….Results: The results of this study found significant increase in HNE levels in sever and critical groups compared to control group.
TÜRK SİNEMASINDA KARA MİZAHIN SİNEMASAL SERÜVENİ: AZİZLER VE SENİ BULDUM YA FİLMLERİNDE DİJİTAL ÇAĞIN PSİKOPATOLOJİSİ
Authors: ELMACI Tuğba , GÜNAYDIN Cansu Kubra
Published: September 2022

Öz: Komedi ve trajedi antik Yunan’dan beri en fazla işlenen iki tür olmuştur. Özellikle komedi türü her coğrafyada kendisine özgü biçim ve temalara bürünen en genel geçer tür olarak sanatın her formunda yerini almıştır. Antik Yunan’dan itibaren de hem trajik hem de komik olan unsurların biraradalığı sözkonusu olmuş ve trajikomik olarak nitelendirilmiştir. Modernizm ile birlikte trajikomik unsurlar; modern dünyanın saçmalığı, duyarsızlığı, hayatın anlamsızlığı, acı ve şiddetin olağan akışı ile mutlu son vaad etmeyen bir dünya kurgusunu içerir. Kendi coğrafyamızda ise trajikomiği türsel bir anlatı yöntemi ile ele alan yazın ve film anlatılarından kara mizah olarak bahsedilmiştir. Nasreddin hoca’dan Aziz Nesin’e kadar Türk mizahı aslında karamizah ekseninde günümüze kadar gelmiş ve en ilişkili alan olan sinemayı da etkilemiştir. Bu anlamda bu çalışma ile karamizah türünün Türk sinemasında hangi temel motifler üzerine inşa edildiği, kara mizahı ortaya çıkaran toplumsal koşulların neler olduğu noktası kavramsal ve tarihsel perspektiften irdelenmiştir. Modern dünyanın saçmalığı ve duyarsızlığı, hayatın anlamsızlığı üzerine kurulan kara mizah anlatılarının çağdaş örneklerinin merkezinde ise; sosyal medyanın esiri olmuş dijital öznelerle karşılaşılmıştır. Bu çalışmada pandemi sürecinde üretilmiş ve pandemi koşullarında dijital platformlarda izleyicisi ile buluşmuş Azizler ve Seni Buldum Ya filmleri üzerinden kara mizahın çağdaş Türk sinemasındaki yükselişi dijital teknolojilerin insanları dönüştürdüğü trajikomik süreç psikanalitik ve tür eleştirisi metodolojisi ile açıklanmaya çalışılmıştır.
Tunable Terahertz Bessel-Beam Launchers
Authors:   Consiglio Nazionale delle Ricerche, Istituto per la Microelettronica e Microsistemi (CNR-IMM), Fuscaldo Walter , Pavone Santi C. ,   Department of Electrical, Electronics and Computer Engineering (DIEEI), University of Catania
Published: September 2022

Bessel-beam launchers are planar devices capable of focusing electromagnetic energy in their radiative near-field region in the form of Bessel beams. Bessel-beam launchers are typically designed to have certain static beam features over a given operating bandwidth in the microwave/millimeter-wave range. Here, taking cues from some recent advancements in the field, we propose innovative architectures capable of generating Bessel beams at terahertz frequencies and featuring a dynamic control of the cover distance. The ideas outlined in this Vision are expected to pave the way for the realization of the first tunable terahertz Bessel-beam launchers.
Financiación con sentido: Estudio para orientar el apoyo de donantes a los derechos de comunidades indígenas y locales, el clima y la conservación
Authors:   Rights and Resources Initiative & Rainforest Foundation Norway
Published: September 2022

Este informe analiza la financiación para la tenencia y la conservación de los Pueblos Indígenas y las comunidades locales entre 2011 y 2020, con la finalidad de aprender de tendencias históricas y plantear oportunidades clave para mejorar la efectividad de esta financiación en los próximos cinco años. Propone que la financiación de donantes sea más acorde a su finalidad, lo que significa que la financiación del clima, de la conservación y de los derechos debe ir canalizada de formas pertinentes y adecuadas para los Pueblos Indígenas y las comunidades locales, y debe garantizar también que las iniciativas y los proyectos financiados estén liderados por las organizaciones de estas comunidades y sean, además, flexibles, de largo plazo, inclusivos en cuanto a género, oportunos y accesibles, y mutuamente responsables.