bluuebunny/crossref_metadata_2025 huggingface dataset:
Anti-dyslipidemic and anti-hypercholesteremic effects of concoction juice: A randomized, double-blind, placebo controlled trial
Authors: Saeed Wajiha , Mahmood Shahid , Mueen-ud-Din Ghulam , Quddoos Muhammad Yousaf
Published: August 2023

Globally, dyslipidemia is an alarming condition, which may cause death. However, its country-wise ratio varies. In Pakistan, it is about 16–20% in both men and women. Dyslipidemia can be defined as the up level quantity of lipids in blood than the average value. The treatment of dyslipidemia can be done by dietary interventions with indigenous sources. The (Concoction) juice has the ability to reduce the low-density lipoprotein (LDL), total cholesterol (TC), triglycerides (TGs). and raise the high-density lipoprotein (HDL) level. For efficacy studies, dyslipidemic females (n = 1010) were approached in different clinics and hospitals of Sargodha. They were approached with biomarkers, that is, lipidemic profile, TC, HDL, urea, creatinine, and TGs. A total of 85 females were selected and they were divided into three groups (T0, L1 and M1). T0 is an experimental (control) group, T1 group has -dyslipidemic patients treated with lab-made juice, and M1 has dyslipidemic patients treated with -market products. After 120 days of treatment, the data were analyzed statistically to validate the results of the study. The -anthropometric and dietary intake was assessed by dyslipidemic volunteers. A significant level of -dyslipidemic biomarker was found in L1. The down level was found in TC (216-184 mg/dL), TGs (215.54-138.46 mg/dL), and LDL (145.64-134.34 mg/dL), and raised level was found in HDL (44.15-54.43 mg/dL). Other parameters that showed a -downward trend were urea (12.73-11.15 mg/dL), uric acid (6.12-5.38 mg/dL), creatinine (1.02-1.0 mg/dL), ALT (55-34 u/l), AST (47-27 u/l), ALP (91.63-83.76 IU/L), bilirubin (0.65 to 0.57 mg/dl), RBCs, WBCs, and Hb. Based on these results, it is concluded that lab-made concoction L1 showed best results overall and is also appropriate and cost effective and further research has to be done on a large scale.
Creating complexity matrix for classifying artificial intelligence applications in e-commerce: New perspectives on value creation
Authors: Babayev Najaf , Israfilzade Khalil
Published: August 2023

This research paper provides a comprehensive exploration of the role of Artificial Intelligence (AI) in value creation within the e-commerce sector, focusing on how task and information complexity affect AI deployment. It first outlines the historical development of value theory and value creation, highlighting the shift from traditional modes to modern interactive and co-creation models. Following this, the paper delves into AI’s potential in various e-commerce dimensions including personalization, product recommendation, supply chain efficiency, and more. The centrepiece of the study is a detailed matrix classifying AI into Automated Intelligence, Assisted Intelligence, and Augmented Intelligence, based on the complexity of tasks they execute and the information they analyse. This research study engaged a panel of fifteen industry and academic experts to critically examine and assign complexity scores to various Artificial Intelligence applications within the e-commerce and similar sectors. The experts evaluated task and information complexity, thereby enabling a classification of the applications into a comprehensible matrix. This classification not only provides a guide for AI system design and evaluation but also enhances understanding of their functional dynamics. The paper contributes theoretically by advancing our understanding of AI as a value creator in e-commerce and practically by offering a roadmap for businesses to adopt and leverage AI technologies. As AI continues to revolutionize the e-commerce sector, the findings of this study provide invaluable insights for businesses seeking to gain a competitive advantage in the digital marketplace.
Exploitation and Exploration Innovation
Authors: Frehner Poffo Rúbia
Published: August 2023

Innovation enables organizations to invest in processes or products that increase their competitive advantage in the market. Thus, this research aims to conduct a bibliometric mapping of scientific production on Innovation Exploitation (incremental innovation) and Innovation Exploration (radical innovation), focusing on scientific articles published in journals in business, administration, accounting, and economics. However, a bibliometric analysis of the publications indexed in the Scopus database from 1995 to 2022 was performed and operationalized using RStudio’s Biblioshiny software. The search was performed by the keywords “Innovation Exploitation”, “Innovation Exploration”, and “Innovation Ambidexterity”, in the fields title, abstract, and keywords. After the filtration processes, the final sample comprised 746 scientific articles. The results of this research present an evolution of the theme over the years. In 1995, innovation was considered the creation or remodeling of products. In contrast, in 2020, innovation was defined as radical or incremental, in which the manager uses innovation as a strategy to increase sales and decreases production costs with the help of technology. Most publications (42.35%) occur after 2017, making clear the importance of the topic in recent years. Between 1995 and 2000, only 22 articles were published, and between 2017 and 2022, there were 408 studies. It was found that the author with the highest number of citations is American, and the country with the highest number of publications is the United States. However, the author with the highest number of publications is Italian, as well as the largest collaboration network, with Italy being the third country with the highest number of publications. Therefore, this study can be a starting point for future research or those interested in the topic.
Avaliação de práticas ESG em bancos listados na [B]³
Authors: Celestino Égon José Mateus , Lima Pereira Mércia de , Camara Renata Paes de Barros
Published: August 2023

Buscou-se analisar se as características de governança corporativa do Conselho de Administração (CA), a estrutura de capital e o desempenho econômico-financeiro das companhias exercem influência sobre a adoção de Políticas Ambientais, Sociais e de Governança (ESG) por parte das instituições bancárias listadas na Brasil Bolsa Balcão [B]3. Para tanto, foram analisados 24 bancos listados na [B]3, via dados anuais disponibilizados no período de 2013 a 2020, na base de dados Thomson Reuters® e no site da [B]3, principalmente por meio da análise de Formulários de Referência das instituições estudadas. Para analisar os resultados, foi realizada a estimação do modelo de regressão Tobit, sendo utilizada como variável dependente a ‘avaliação de práticas ESG’, medida por um índice que varia de 0 (para empresas sem práticas ESG e/ou sem avaliação ESG na base Refinitiv®) a 100 (empresas com melhores práticas ESG) e, para variáveis independentes, foram utilizadas caracterizações de empresas bancárias e do CA, estrutura de capital e indicadores de desempenho econômico-financeiro. Com base nos resultados, notou-se que o tamanho dos bancos e a diversidade de gênero do CA apresentaram estatísticas positivas e significativas, demonstrando que os bancos maiores e com mais presença de mulheres no conselho tendem a manter as melhores práticas de ESG. Por outro lado, foram observadas relações estatísticas negativas e significativas entre a emissão de American Depositary Receive (ADR's), o número de membros independentes do Conselho e as práticas de Board Interlocking (B.I.) e as melhores práticas ESG. Contudo, o estudo contribui para a literatura com o entendimento dos eventos ESG dos bancos brasileiros e com as demandas regulatórias do Banco Central do Brasil, em decorrência das normas com exigências de Responsabilidade Socioambiental por parte do órgão regulador, bem como com as cobranças dos stakeholders e do mercado por melhores práticas ESG dos bancos.
Assessment of ESG practices in banks listed in [B]³
Authors: Celestino Égon José Mateus , Lima Pereira Mércia de , Camara Renata Paes de Barros
Published: August 2023

We sought to analyze whether the corporate governance characteristics of the Board of Directors (BoD), the capital structure, and the economic and financial performance of the firms influence the adoption of Environmental, Social, and Governance Policies (ESG) by banking institutions listed on the Brasil Bolsa Balcão [B]3. To this end, 24 banks listed in [B]3 were analyzed, via annual data made available from 2013 to 2020, in the Thomson Reuters® database and on the [[B]3 website, mainly through the analysis of Reference Forms of the institutions studied. To analyze the results, the Tobit regression model was estimated, using as a dependent variable the ‘assessment of ESG practices’, measured by an index ranging from 0 (for firms without ESG practices and/or without ESG assessment in the Refinitiv® database) to 100 (firms with best ESG practices) and, for independent variables, characterizations of banking firms and BoD, capital structure, and economic-financial performance indicators were used. Based on the results, it was noted that the size of the banks and the gender diversity of the BoD presented positive and significant statistics, demonstrating that larger banks with more women on the board tend to maintain ESG best practices. On the other hand, negative and significant statistical relationships were observed between the issuance of American Depositary Receive (ADRs), the number of independent Board members, and Board Interlocking (B.I.) practices and ESG best practices. However, the study contributes to the literature with the understanding of ESG events of Brazilian banks and with the regulatory demands of the Central Bank of Brazil as a result of the rules with requirements of Social and Environmental Responsibility by the regulatory body, as well as with the demands of stakeholders and the market for best ESG practices of banks.
Avaliação econômica por receita tarifária das empresas metroferroviárias brasileiras
Authors: Silva Brum Maria Cecilia da , Wickstrom Alves Tiago
Published: August 2023

O transporte metroferroviário é fundamental para mobilidade urbana e há um reconhecimento da necessidade de subsídio para que ele possa operar de forma eficiente do ponto de vista social. Assim, esta pesquisa tem como objetivo analisar, por meio de funções de custos, a viabilidade econômica por receita tarifária de empresas de transporte metroferroviário. Metodologicamente, usou-se como referência oito empresas que representam 90% dos passageiros transportados no sistema metroferroviário brasileiro, para a captação dos custos por passageiros e estimação das funções de custos médios por Mínimos Quadrados Ordinários. Os resultados indicam possibilidade de ganhos com melhor ocupação da escala e nível de eficiência, porém, esses não viabilizam as operações com as tarifas praticadas pelas empresas públicas. Esses resultados lançam luz para a gestão das políticas públicas tarifárias, justificando essa pesquisa.
Determinants for disclosure of the key audit matters in non-financial companies of B3
Authors: Dal Bem Venturini Lauren , Alberto Barbetta Pedro , Alonso Borba José , Flach Leonardo
Published: August 2023

This research analyzes the determinants of the quantity of key audit matters (KAM) reported in audit reports from 2016 to 2019 of the non-financial companies listed on B3. The longitudinal regression model for panel data - Poisson’s Log-Linear was applied to an annual sample of at least 272 companies, resulting in 1,198 reports and 3,295 KAM (dependent variable), considering as explanatory variables the aspects of the auditor, the auditee, and corporate governance mechanisms. The findings demonstrate that being audited by the big four is negatively associated with the quantity of KAM. This may be due to the big four or not reporting the same mean number of KAMs per company. Auditors of larger companies, less profitable and with greater operational risk, disclose more KAM, probably aiming to ensure their independence. The audit committees were not statistically significant, not impacting the quantity of KAM reported. The results contribute to the literature on factors that affect the disclosure of KAM in a non-European context (Bepari et al., 2022) with four years of data, and to companies, auditors, and regulatory and supervisory bodies, through Poisson’s multilevel regression, which is an appropriate approach for structured counting data in clusters of relatively similar observations (panels). This advances the studies by Ferreira and Morais (2020) and Guedes et al. (2021), who used ordinary least squares (OLS), and Colares et al. (2020), who used the Chi-square test in one- or two-year analyses of characteristics that tend to establish the quantity of KAM in Brazil.
Flow and let it flow
Authors: Santos Ana Paula dos , Lizote Suzete Antonieta , Teston Sayonara de Fátima
Published: August 2023

This study aimed to verify the intensity of the state of flow at work in the perception of accountants who work in accounting services firms. The research, of a descriptive nature, had a quantitative approach, applying a self-completion questionnaire based on the model of Freitas, Damásio, Haddad, and Koller (2019) that highlights the state of flow at work in three dimensions: pleasure at work, intrinsic motivation, and absorption. The respondents were 154 accountants from accounting services firms in Itajaí (Santa Catarina). The indicators were validated through Exploratory Factor Analysis, and descriptive statistics were used to verify the intensity of the dimensions. The results showed that the dimension of the state of flow at work that presented a high degree of intensity was pleasure at work, followed by intrinsic motivation at work and absorption, which reached a medium degree. Thus, it was evidenced that the accountants analyzed, when performing their tasks, enter a state of flow, emphasizing pleasure at work, especially in the statement, “I do my job with great pleasure”. Empirically, knowledge of the state of flow can contribute to the management practices being conducted to promote well-being and thus increase engagement and the way of experiencing work. Theoretically, the results contribute to the expansion of studies in organizational behavior.
Sticky Leverage: Comment
Authors: Ajello Andrea , Perez-Orive Ander , Szőke Bálint
Published: August 2023

We revisit the role of long-term nominal corporate debt for the transmission of inflation shocks in the general equilibrium model of Gomes, Jermann, and Schmid (2016, henceforth GJS). We show that inaccuracies in the model solution and calibration strategy lead GJS to a model equilibrium in which nominal long-term debt is systematically mispriced. As a result, the quantitative importance of corporate leverage in the transmission of inflation shocks to real activity in their framework is 6 times larger than what arises under the rational expectations equilibrium.
Effects of Partial Replacement of Sugar with Fig Syrup on Bacillus coagulans Survival and Physicochemical Properties of Probiotic Ice Cream
Authors: Janipour Reza , Shekarforoush Seyed Shahram , Ghorbani Samira , Gheisari Hamid Reza
Published: August 2023

Research background. Various sectors of the food industry demand the enrichment of food with functional compounds. Probiotic products with valuable nutritional and therapeutic properties have attracted great attention in the fields of industry, nutrition and medicine. The aim of the present study is to investigate the sensory and physicochemical properties of probiotic ice cream containing fig syrup and to evaluate the survival of Bacillus coagulans after 90 days of storage at –18 °C.
Experimental approach. In this study, four experimental groups of ice cream were produced as follows: plain dairy ice cream (without additives), ice cream containing 109 CFU/g B. coagulans, ice cream containing 25 % fig syrup as sugar substitute and ice cream containing 25 % fig syrup as sugar substitute and 109 CFU/g B. coagulans. They were stored at –18 °C for 3 months. Texture, pH, acidity and viscosity were analysed and microbial counts were determined after 1, 30, 60 and 90 days of storage. The organoleptic evaluation was carried out on days 1 and 90.
Results and conclusions. The results showed that during the initial freezing process and the transformation of the mixture into ice cream, the number of B. coagulans decreased from 109 to 107 CFU/g, without significant changes observed over the 90-day period. No significant changes were found in the sensory and textural properties of the samples either. Replacement of 25 % sugar with fig syrup reduced the pH, increased the acidity of the ice cream and improved their viscosity. In conclusion, the production of functional ice cream using fig syrup and B. coagulans is recommended for their health benefits.
Novelty and scientific contribution. The results of this study can be used to prepare functional and healthy foods. Our results suggest that fig syrup has the potential to be used as a natural sweetener or sugar substitute in various products.
Xylanase Production by Solid-State Fermentation for the Extraction of Xylooligosaccharides from Soybean Hulls
Authors: Šekuljica Nataša , Jakovetić Tanasković Sonja , Mijalković Jelena , Simović Milica , Pavlović Neda , Đorđević Nikola , Culetu Alina , Gazikalović Ivana , Luković Nevena , Bakrač Jelena , Knežević-Jugović Zorica
Published: August 2023

Research background. The development of a novel process for the production of xylooligosaccharides (XOS) based on the 4R concept is made possible by the integration of numerous techniques, especially enzymatic modification together with the physical pretreatment of renewable materials. This study aims to integrate the use of agricultural wastes for the production of xylanase by a new strain of Penicillium sp. and value-added products, XOS.
Experimental approach. For the production of xylanase, a solid-state fermentation was performed using wheat bran as substrate. To obtain the most active crude extract of xylanase, the time frame of cultivation was first adjusted. Then, the downstream process for xylanase purification was developed by combining different membrane separation units with size exclusion chromatography. Further characterisation included determination of the optimal pH and temperature, determination of the molecular mass of the purified xylanase and analysis of kinetic parameters. Subsequently, the hydrolytic ability of the partially purified xylanase in the hydrolysis of alkali-extracted hemicellulose from soybean hulls was investigated.
Results and conclusions. Our results show that Penicillium rubens produced extracellular xylanase at a yield of 21 U/g during solid-state fermentation. Using two ultrafiltration membranes of 10 and 3 kDa in combination with size exclusion chromatography, a yield of 49 % and 13-fold purification of xylanase was achieved. The purified xylanase (35 kDa) cleaved linear bonds β-(1→4) in beechwood xylan at a maximum rate of 0.64 μmol/(min·mg) and a Michaelis constant of 44 mg/mL. At pH=6 and 45 °C, the purified xylanase showed its maximum activity. The xylanase produced showed a high ability to hydrolyse the hemicellulose fraction isolated from soybean hulls, as confirmed by thin-layer chromatography. In the hydrothermally pretreated hemicellulose hydrolysate, the content of XOS with different degrees of polymerisation was detected, while in the non-pretreated hemicellulose hydrolysate, the content of xylotriose and glucose was confirmed.
Novelty and scientific contribution. Future research focusing on the creation of new enzymatic pathways for use in processes to convert renewable materials into value-added products can draw on our findings.
Elemental, phytochemical, and toxicological assessment of Cissus rotundifolia (Forssk.) Vahl
Authors: Mshengu Bongiwe P. , Buthelezi Cordelia Z. , Moodley Roshila
Published: August 2023

Cissus rotundifolia (Forssk.) Vahl. (Vitaceae) is a wild plant that is commonly used by communities from rural areas as a food and medicine. There are limited studies on the phytochemical composition and the impact of soil quality on the elemental distribution in this plant. In this study, we report a phytochemical analysis to identify the phytocompounds responsible for the reported biological activities of C. rotundifolia. We also examined the impact of soil quality on elemental uptake by the edible parts of C. rotundifolia collected from eight geographical locations in KwaZulu-Natal (South Africa) to assess the nutritional benefits and potential heavy metal toxicities. Three secondary metabolites (stigmasterol, β-sitosterol, and pheophytin a) were isolated, and their structures were characterised by high-resolution mass spectrometry and nuclear magnetic resonance data. The plant was found to contribute adequately to the recommended dietary allowances for essential nutrients without exceeding tolerable upper intake limits and with low concentrations of toxic heavy metals. The average concentrations of microelements in the edible parts were found to be in decreasing order of Fe>Mn>Se>Zn>Cu>Cr>Ni>Co. The bioaccumulation factors indicate that the plant controls the uptake of metals from the soil and would make a good indicator and biological monitor for cadmium toxicity. However, a health risk assessment exposed carcinogenic risks on regular consumption of the plant obtained from sites close to pollution sources, such as roads and landfills. The findings from this study show the synergies when consuming medicinal plants and provide evidence for C. rotundifolia as a nutraceutical.
Significance:
This study provides additional scientific knowledge on the phytochemical composition of C. rotundifolia. Three phytocompounds (stigmasterol, β-sitosterol, and pheophytin a) were isolated, and their presence may be correlated to this plant’s antidiabetic, anti-inflammatory, and antibacterial properties. This study shows that C. rotundifolia contributes adequately to the recommended dietary allowances for essential elements, and the plant is safe for human consumption if collected from non-polluted sites. The carcinogenic and non-carcinogenic estimates for the toxic metals due to consumption of the plant signify the possibility of developing cancer over time if the plant is consumed frequently from polluted sites.
Future climate change in the Agulhas system and its associated impact on South African rainfall
Authors: Daher Houraa , Kirtman Ben P.
Published: August 2023

South African climate variability has been linked to changes in both the Agulhas system and external forcing (i.e. CO2 and ozone). We analysed future climate change in the Agulhas system volume transport and its associated impacts on South Africa’s precipitation using the Community Climate System Model version 4 as part of the Coupled Model Intercomparison Project, phase 5. Output from one historical and three future greenhouse gas emission scenarios were examined to project various climate storylines. We found that the Agulhas Current volume transport decreases across all three scenarios and that the current displays a strong baroclinic component with an increase in transport at the surface and decrease at intermediate depths. Agulhas leakage was found to increase with historical emissions. Additionally, an east-west dipole pattern for convective precipitation was found over South Africa, with an increase over the eastern region related to an increase in greenhouse gas emissions and a decrease in the western region linked to the location of Hadley cell edge latitude. Moving into the 21st century, future predictions in regional climate variability are shown to be dependent on the intensity of greenhouse gas emissions and are extremely important for South Africa, a region prone to drought and flooding and home to a large population dependent on rain-fed agriculture.
Significance:

Future climate variability in the Agulhas system and South African region is heavily dependent on changes in external forcing.
The Agulhas Current volume transport decreases as the greenhouse gas emissions continue to increase and a strong baroclinic component is found with an increase in transport at the surface and a decrease at the intermediate depths.
A strong east-west dipole precipitation pattern is found over South Africa with the increase in the eastern region related to the increase in greenhouse gas emissions and the decrease in the western region related to the location of the Hadley cell edge latitude.
Urban expansion, subnormal agglomerations and provision of sanitation services: a case study of the Metropolitan Region of Belém
Authors: Ferreira de Souza Caio Cezar , Dos Santos Saraiva Joyce , Bahia Lopes Maria Lúcia
Published: August 2023

The process of urban growth in Brazil remains accelerated and presents a wide variety of realities. In this article, we aim to analyze the urban expansion in the Metropolitan Region of Belém (RMB), verifying whether it occurred intensively or extensively, and whether this expansion was accompanied by an increase in subnormal agglomerations and the provision of sanitation services. The methodology was based on the elaboration of land use and occupation maps in the urban area of the RMB and on obtaining data referring to subnormal agglomerations and the scope of basic sanitation services, made available by the Brazilian Institute of Geography and Statistics. The results showed that the RMB had more extensive urban expansion in the 1990s, with a smaller expansion between 1999 and 2017. However, the coverage of basic sanitation services did not follow this expansion process and in the spaces inserted by the expansion process subnormal clusters were concentrated.
LRRK2 and LAMP1 immunofluorescence staining in various cell lines v1
Authors: Chen Siyu
Published: August 2023

This protocol is being used to test the antibody , as well as . Please note that after multiple rounds of optimization, anti-LRRK2 antibody generates significant non-specific signals in the LRRK2 KO cell lines so this antibody may not be reliable for Immunofluorescence staining experiments. The protocol can be used for general IF experiments.
Recommendations for anesthesia management of hip and hip surgery: literature review
Authors: Morozov Dmitry V. , Koriachkin Viktor A.
Published: August 2023

The authors analyzed studies on the issues of perioperative analgesia in hip and hip joint surgery. Based on the analysis, modern recommendations are presented regarding the choice of optimal anesthetic techniques for proximal femoral fractures and hip arthroplasty. Early surgical intervention in older patients contributes to the restoration of the supporting function of the limb, enables rapid rehabilitation, and reduces the risk of life-threatening complications. This requires pain relief for preoperative preparation and high-quality intraoperative and postoperative pain relief, allowing early rehabilitation of the patient. The review included materials from recent congresses, and webinars of the European Society of Regional Anesthesia Pain Treatment. According to many authors, ileofascial blockade is the method of choice for preoperative anesthesia for proximal femoral fractures. Variants of the blockades of the branches of the lumbar and sacral plexuses in various anatomical spaces and plane blocks are considered. In addition, recommendations of the PROSPECT group (Procedure Specific Postoperative Pain Management) on the use of various technologies in the perioperative period are considered based on data from multicenter randomized trials and meta-analyses in relation to a specific procedure. The effectiveness of new approaches to the branches of the lumbar plexus was also considered, for example, suprainguinal ileofascial blockade and blockade of the pericapsular nerves. Anesthesiologists have used relatively new and traditional tools available to reduce pain and speed up postoperative recovery for patients with injuries and undergoing surgery for the proximal femur. Although the effectiveness of not all of them is confirmed by evidence-based medicine, clinical practice shows a positive effect on their use.
Multimodal approach to perioperative protection in children in abdominal surgery: A prospective comparative study
Authors: Satvaldieva Elmira A. , Faiziev Otabek Ya.
Published: August 2023

OBJECTIVE: To increase the effectiveness of perioperative protection by using combined multimodal analgesia (CMA) with epidural blockade (EA) with bupivacaine in combination with low-flow anesthesia with sevoflurane in traumatic abdominal surgery in children.
MATERIALS AND METHODS: A prospective comparative study was conducted (n=102, from 1 to 17 years). Surgical planned pathology: Hirschsprung disease, Ledd and Payr syndrome, liver echinococcosis, enterocystoma, pancreatic cyst. Study period: 20182022. Patients were divided into two groups depending on the technique of anesthesia and management of the postoperative period. Group 1 (n=55) received CMA + EA with bupivacaine 0.5%. In the postoperative period prolonged EA with bupivacaine 0.25% 0.51 mg/kg. Comparison group 2 (n=47) traditional general anesthesia based on opioids. For the treatment of postoperative pain syndrome (PPS) promedol 0.3 mg/kg. The effectiveness of perioperative analgesia in pediatric abdominal surgery, the time of development and intensity of postoperative pain syndrome were evaluated.
RESULTS: The data obtained as a result of the study clearly showed that the advantages lie behind the optimized method of combined multimodal analgesia CMA + EA with bupivacaine 0.5%. In general, the effectiveness of CMA in combination with epidural analgesia in the intraoperative period was quite high. Additional intraoperative administration of fentanyl was registered in 8 (14.5%) of cases. The stability of hemodynamic parameters and neuroendocrine status was noted in almost all patients of the main group. Analyzing the time of development and intensity of PPS, it can be argued that patients of group 1 had better indicators: the duration of the pain-free period was 2 times longer and the intensity of PPS was lower than in children of group 2. Motor blockade gradually resolved in patients on average, after 20946 minutes. By this time, there was a recovery of the sensation of a pinprick and motor activity in 32 (58.1%) of patients according to the Bromage 2 scale. Analysis of the results of an oral survey of patient satisfaction with pain relief conducted 24 hours after surgery showed that in group 1 the number of cases 43 (78.1%) satisfied with the level of pain relief was 1.5 times higher compared to the control group 24 (51.1%).
CONCLUSION: Combined multimodal analgesia in combination with epidural blockade with bupivacaine in traumatic abdominal surgery in children provides sufficient perioperative stability of the hemodynamic and neuroendocrine status, significantly reduces the pharmacological burden, reduces complications, early activation of patients and rapid postoperative rehabilitation compared to the traditional method.
Comparison of the effect of combined general and regional anesthesia on the cognitive functions of women of reproductive age: retrospective observational study
Authors: Chernykh Oksana A. , Lakhin Roman E. , Shchegolev Alexey V.
Published: August 2023

BACKGROUND: Depression and cognitive dysfunction in the postoperative period may be associated with pregnancy, surgery, and type of anesthetic support.
OBJECTIVE: To perform a comparative assessment of the effect of combined general and regional anesthesia on memory and attention in pregnant and nonpregnant women.
MATERIALS AND METHODS: The study involved 120 women of reproductive age who were admitted for surgery. According to the indications, they received various anesthesia types depending on their somatic status. The cognitive potential of the patients and indicators of memory and attention, anxiety, and depression were evaluated using specially selected tests before surgery and three days after surgery. The effect of anesthesia on pregnant women during planned operative delivery was studied, and planned interventions in gynecology were used for comparison.
RESULTS: The MOS test scores in all groups were reduced, and they indicated a reduced cognitive potential in nonpregnant women [26.2 (26.9; 25.5) and 24 (24.59; 23.44)] under general anesthesia (p 0.003) and pregnant women [25.2 (25.7; 24.7) and 24.6 (25.36; 23.84)] under general anesthesia (p 0.004). After the operation under OA, the results worsened, and statistical differences were revealed. The level of attention in pregnant women decreased according to the results of the Wexler test after surgery in the general anesthesia group [4.5 (5.1; 3.9) and 3 (3.46; 2.54), p 0.006], and in the regional anesthesia group, the results decreased but to a lesser extent degree [5 (5.8; 4.2) and 3.5 (4.2; 2.8, p 0.005], showing statistical difference. According to the results of the Benton test after surgery in the general anesthesia group, visual short-term memory decreased in pregnant women [6.15 (6.75; 5.55) and 4 (4.86; 3.14), p 0.002], and in the regional anesthesia group, the results decreased, but to a lesser extent [6.2 (6.9; 5.5) and 4.5 (5.2; 3.8, p 0.012], and statistical differences were noted.
CONCLUSION: The effect of combined general and regional anesthesia led to the development of cognitive dysfunction, increased depression, and changes in memory and attention.
An extended brachial plexus blockade with an original method of catheter fixation: clinical case
Authors: Yamshchikov Oleg N. , Marchenko Alexander P. , Emelyanov Sergey A. , Ivanova Olga D. , Pavlova Ksenya A.
Published: August 2023

BACKGROUND: For extended blockade of the brachial plexus from the supraclavicular access, the catheter is fixed in the supraclavicular region. Owing to the anatomical features of the supraclavicular fossa and the short inner part of the catheter, this fixation method cannot be fully considered reliable and convenient both for the personnel operating the catheter and the patient. The most convenient place for fixing the catheter is the infraclavicular region because of its flat surface. If a catheter is installed to the brachial plexus from the supraclavicular access and the catheter is passed under the skin in the infraclavicular region, then the catheter exit site on the skin will be located further from the surgical intervention area and the inner part of the catheter will be larger.
CLINICAL CASE DESCRIPTION: This study describes a clinical case of blockade of the brachial plexus by interscalene access with catheterization for prolonged analgesia via supraclavicular access and fixation of the catheter under the skin in the subclavian region in an older patient with polymorbidity during surgical treatment of a closed fracture of the middle third of the humerus. In anesthetic provision, when inducing brachial plexus blockade via a supraclavicular approach, the catheter was fixed in the subcutaneous tunnel of the infraclavicular region for prolonged blockade of the brachial plexus.
CONCLUSION: This fixation method prevented internal and external dislocation of the catheter, which contributed to high-quality and long-term postoperative analgesia, early patient activity, and absence of infectious complications and created comfortable conditions for the handling of the catheter for both the medical staff and the patient.
Possibilities of using regional anesthesia with diode-laser transscleral cyclophotocoagulation in children: description of clinical cases
Authors: Bersenev Sergei V. , Konyaeva Julia M. , Yurchenko Olga M.
Published: August 2023

BACKGROUND: Diode-laser transscleral cyclophotocoagulation (DLTCPC) is one of the most commonly used treatment options for intraocular pressure reduction in refractory glaucoma in adult and pediatric patients. To achieve the necessary effect, these operations often have to be repeated. Repeated general anesthesia inductions increase the risk of cognitive disorders in children and sometimes do not provide sufficient postoperative analgesia.
OBJECTIVE: To analyze the results of transscleral DLTCPC in children under regional anesthesia and identify factors predisposing to the choice of this anesthesia method.
MATERIALS AND METHODS: The study included 33 children aged 1017 years who had undergone 57 transscleral DLTCPCs in IRTC Eye Microsurgery Ekaterinburg Center between 01.09.2017 to 31.08.2022. In each case, the anesthesia method was selected individually according to the principle of reasonable sufficiency.
RESULTS: Of 57 operations, 36 (73%) were performed under regional and 21 (37%) were under general anesthesia. Factors that favor regional anesthesia include (1) psycho-emotional maturity of the patient, (2) older age, and (3) greater number of previous operations. An algorithm for the selection of the anesthesia method is presented, as well as a plan for the conversation with the patient and his / her legal representatives. Regional anesthesia provides good intra- and postoperative anesthesia and prophylaxis of postoperative cognitive disorders in children who are emotionally stable and suitable for this type of anesthesia.
CONCLUSION: Considering the psycho-emotional features of children, general anesthesia remains the main method in ophthalmic anesthesiology. Nevertheless, following the principle of reasonable sufficiency and accounting for the short duration of DLTCPC and the large extent of general anesthesia survived by these children previously, regional anesthesia can be successfully used in a portion of these children.
Çift balonlu enteroskopi: Tek merkez deneyimi
Authors: ERKUT Murat
Published: August 2023

Giriş ve Amaç: Çift balonlu enteroskopi ince bağırsak anormalliklerinin tanısının konulması ve girişimsel işlemlerinin yapılmasında önemli bir prosedürdür. Bu çalışmada Doğu Karadeniz Bölgesi’ndeki çift balonlu enteroskopi işlemi uygulanan hastaların değerlendirilmesi planlandı. Gereç ve Yöntem: Bu çalışmada Ağustos 2017 - Ocak 2023 tarihleri arasında; hastaların çift balonlu enteroskopi yapılma endikasyonları, demografik özellikleri, laboratuvar tetkikleri, görüntüleme yöntemleri, endoskopik bulguları, histopatolojik sonuçları, endoskopik girişimsel işlemler ve komplikasyonları retrospektif olarak değerlendirildi. Bulgular: Hastaların 30’u (%56) erkek, 24’ü (%44) kadın olup, ortanca enteroskopi yapılma yaşı 52 (17 - 84) /yıldı. En sık çift balonlu enteroskopi yapılma endikasyonları gizli gastrointestinal kanama (%28) ve aşikar gastrointestinal kanama (%22) idi. Enteroskopide en sık izlenen lezyon ülser, inflamasyon veya mukozal lezyon (%17) ve en sık konulan tanı Crohn hastalığı (%15) idi. Görüntüleme tetkikleri normal olan 10 hastanın 4’ünün (%40) endoskopi bulguları anormal idi ve bu hastalar adenokarsinom (%10), polip (%10), anjiodisplazi (%10) ve Crohn hastalığı (%10) tanıları aldı. Endoskopi bulguları normal olan, fakat görüntüleme yöntemlerinde anormallik izlenen 1 (%4) hastaya lenfoma tanısı konuldu. Çift balonlu enteroskopi yapılma endikasyonu gastrointestinal kanama olan hastalarda, sıklıkla tümöral (%11) ve vasküler lezyonlar (%11) izlendi ve bu hastaların çoğuna kanser ve anjiodisplazi tanısı konuldu. Gastrointestinal kanama dışındaki nedenler ile çift balonlu enteroskopi yapılan hastalarda ise, en sık ülser, inflamasyon veya mukozal lezyon (%33) tespit edildi ve bu hastaların çoğuna Crohn hastalığı (%26) tanısı konuldu. Sonuç: Çift balonlu enteroskopi ince bağırsak hastalıklarının tanısının konulmasında ve terapötik işlemlerin yapılmasında etkili ve güvenli bir prosedürdür. Bununla birlikte, ince bağırsak hastalığı için çift balonlu enteroskopi yanında klinik ve radyolojik bulgularda dikkate alınmalıdır.
Upaya Meningkatkan Keterampilan Forehand Smash untuk Atlet Bulutangkis Usia 12-15 Tahun Menggunakan Teknik Bervariasi pada Atlet Pb. Tunas Harapan Kabupaten Tulungagung
Authors: Dipoyanti Monica Silvia , Adi Sapto , Fadhli Nurrul Riyad , Rahayuni Kurniati
Published: August 2023

Abstract: One of the basic badminton techniques that many players use to kill the opponent's game is the smash. This study aims to improve the basic motion skills of forehand smash by using a variety of exercises for beginner badminton athletes aged 12-15 years PB. Tunas Harapan Tulungagung Regency. By using a variety of exercises, athletes will not get bored with other training programs. In cycle 1 there was an increase but still had a less value, then in cycle 2, forehand smash technique training was carried out at the age of 12-15 years, giving a rapid increase in athletes aged 12-15 years for forehand smash. techniques using various training methods.

Abstrak: Salah satu teknik dasar bulutangkis yang banyak digunakan pemain untuk membunuh permainan lawan adalah smash. Penelitian ini bertujuan untuk meningkatkan keterampilan gerak dasar pukulan forehand smash dengan menggunakan latihan variasi untuk atlet bulutangkis pemula usia 12-15 tahun PB. Tunas Harapan Kabupaten Tulungagung. Dengan menggunakan latihan bervariasi, maka atlet tidak akan bosan dengan program latihan yang lain. Pada siklus 1 mengalami peningkatan namun masih memiliki nilai yang kurang baik, maka peneliti melakukan siklus 2 pada latihan teknik forehand smash pada usia 12 – 15 Tahun memberikan dampak peningkatan pesat pada atlet berusia 12 -15 Tahun untuk teknik forehand smash yang menggunakan metode variasi latihan.
Upaya Meningkatkan Teknik Pukulan Backhand Dropshot Menggunakan Metode Drill Bagi Atlet Bulutangkis PB. Nikko Steel Kota Malang
Authors: Lazuardi Cholid Bardan , Januarto Oni Bagus , Tomi Agus , Adi Sapto
Published: August 2023

Abstract: This study aims to improve the backhand dropshot skills of badminton using the drill method for badminton athletes in PB. Nikko Steel Malang City. Based on the results of the initial observations that have been made by the researchers, the results of the lowest success rate of the hitting technique are the backhand dropshot. This research is a type of sports action (PTO) through descriptive qualitative and quantitative descriptive methods taking research subjects as many as 12 athletes aged 8-13 years. There were 2 cycles and each cycle consisted of 5 meetings. The results of the first cycle, namely the attitude of preparation, got a result of 64.58 percent. In the attitude indicator, the results obtained are 60.11 percent. While in cycle 2, namely the attitude of preparation, the results obtained are 83,33 percent. On the indicator of the attitude of hitting the results obtained that is equal to 84.52 percent. In cycle 1 and cycle 2, there was a significant increase and had exceeded the completeness criteria of 75 percent. There is a conclusion that in giving the drill method to athletes, they can develop badminton backhand dropshot technique skills in athletes aged 8-13 years in PB. Nikko Steel Malang City.

Abstrak: Penelitian ini bertujuan untuk meningkatkan keterampilan pukulan backhand dropshot bulutangkis memakai metode drill untuk atlet bulutangkis di PB. Nikko Steel Kota Malang. Bersumber hasil observasi awal yang telah dilaksanakan penulis diperoleh hasil tingkat keberhasilan teknik pukulan paling rendah yaitu backhand dropshot. Penelitian ini berjenis tindakan olahraga (PTO) melalui metode deskriptif kualitatif serta deskriptif kuantitatif mengambil subjek penelitian sebanyak 12 atlet usia 8-13 tahun. Dilakukan 2 siklus dan setiap siklusnya terdiri dari 5 kali pertemuan. Hasil dari siklus 1 yaitu pada sikap persiapan mendapat hasil sebesar 64,58 persen. Pada indikator sikap memukul hasil yang didapatkan yakni 60,11 persen. Sedangkan dalam siklus 2 yaitu pada sikap persiapan didapatkan hasil dari yakni senilai 83,33 persen. Dalam indikator sikap memukul hasil yang diperoleh yaitu senilai 84,52 persen. Dalam siklus 1 serta siklus 2 memperlihatkan adanya peningkatan yang signifikan dan telah melampaui kriteria ketuntasan sebesar 75 persen. Terdapat simpulan bahwasanya dalam memberi metode drill kepada atlet dapat mengembangkan keterampilan teknik pukulan backhand dropshot bulutangkis pada atlet usia 8-13 tahun di PB. Nikko Steel Kota Malang.
Survei Masalah yang Dihadapi Oleh Guru PJOK dalam Melaksanakan Pembelajaran Pada Masa Pandemi Covid-19 Di SMA Negeri se-Kabupaten Banyuwangi
Authors: Nugraha Dwiyan Kusuma , Mu’arifin Mu’arifin , Winarno M. E. , Hariyoko Hariyoko
Published: August 2023

Abstract: This study aims to find out what are the problems with implementing PE learning during the Covid-19 pandemic at Public High School in Banyuwangi Regency. The research design used was descriptive quantitative and descriptive qualitative with survey method. The sample in this study were 29 PE teachers. The instruments used were interviews and questionnaires distributed at the PE MGMP meeting in Banyuwangi on 09 June 2022 with 20 questions. From the results of research that has been carried out by researchers that there are problems in the aspect of learning planning that has been filled in by 29 respondents, 62 percent (agree) have experienced problems, in the aspect of learning implementation, 69 percent (agree) have experienced problems, and the aspect of learning evaluation got the results of 74 percent (agree) that they had problems. It can be concluded that during the covid-19 pandemic, teachers continued to carry out learning using daring methods, but in general they were less effective. On the problems faced, PE teachers obtain PE learning solutions so that they can be implemented in accordance with learning objectives.

Abstrak: Tujuan dari penelitian ini yaitu untuk mengkaji dan mengetahui permasalahan pembelajaran PJOK pada masa pandemi Covid-19 di SMA Negeri se-Kabupaten Banyuwangi. Desain penelitian yang digunakan deskriptif kuantitatif dan kualitatif dengan metode survei. Subjek dalam penelitian ini adalah 29 guru PJOK. Instrumen yang digunakan berupa wawancara dan kuesioner yang disebarkan pada waktu rapat MGMP PJOK di Banyuwangi pada tanggal 09 juni 2022 dengan 20 pertanyaan. Dari hasil penelitian yang sudah dilaksanakan oleh peneliti bahwa ada permasalahan di dalam aspek perencanaan pembelajaran yang sudah di isi oleh 29 responden mendapatkan hasil 62 persen (setuju) bahwa mengalami permasalahan, dalam aspek pelaksanaan pembelajaran mendapatkan hasil 69 persen (setuju) bahwa mengalami permasalahan, dan aspek evaluasi pembelajaran mendapatkan hasil 74 persen (setuju) bahwa mengalami permasalahan. Kesimpulan dari penelitian ini yaitu saat pandemi covid-19 guru melaksanakan pembelajaran dengan metode daring, namun sepenuhnya belum efektif. Banyak permasalahan yang sudah dihadapi oleh guru PJOK dalam pembelajaran daring, salah satunya pembelajaran terhambat akibat jaringan dan kuota internet yang kurang memadai. Dari suatu permasalahan tersebut guru mendapatkan solusi salah satunya pemberian bantuan dana oleh sekolahan dan bantuan kuota dari pemerintah agar pembelajaran terlaksana sesuai dengan tujuan pembelajaran PJOK.