bluuebunny/crossref_metadata_2025 huggingface dataset:
Treatment of Obstructive Sleep Apnea and Simple Snoring: Efficacy of a New Mandibular Advancement Device
Authors: Cremonini Francesca , Poma Gaia , Palone Mario , Pellitteri Federica , Guidorzi Jenny , Colabianchi Valentina , Stomeo Francesco , Lombardo Luca
Published: May 2024

The following prospective study has the aim of evaluating the efficiency of the F22 MAD (mandibular advancement device), a new oral device for the treatment of OSAS (Obstructive Sleep Apnea Syndrome) and snoring. Methods: AHI (apnea-hypopnea index), ODI (Oxygen Desaturation Index), snoring percentage, time spent in the supine position, and Epworth Sleepiness Scale score were evaluated in 19 patients with snoring, mild to moderate OSAS, or severe OSAS who declined CPAP (Continuous Positive Air Pressure) treatment, before and after the application of the F22 MAD. Results: The median value of AHI varied from 15.6 ± 10.7 to 5.7 ± 5.7; the median value of ODI varied from 13.4 ± 8.8 to 6.2 ± 5.2; the median value of the percentage of snoring varied from 30.7 ± 7 to 7.5 ± 10.8, except for the patient who has severe OSAS who increased their value. The value obtained by the self-completion of the ESS questionnaire (Epworth Sleepiness Scale) underwent a statistically significant variation, while clinically significant for 13\19 patients who obtained a reduction of the value >/= of 2 points. Conclusions: It is possible to conclude that the F22 MAD is effective in the treatment of patients with mild and moderate OSAS or simple snoring, reducing the polysomnographic outcomes with statistically and clinically significant results in terms of reduction of AHI, ODI and percentage of snoring.
In Vitro Evaluation of Surface Roughness and Color Variation after Two Brushing Protocols with Toothpastes Containing Different Whitening Technologies
Authors: Lobito Angel , Colaço Catarina , Costa Joana , Caldeira Jorge , Proença Luís , Mendes José João
Published: May 2024

The aim was to evaluate the effect of different whitening toothpastes on the enamel surface roughness and color variation. Twenty-four molars were sectioned and divided into eight groups (n = 3) considering the following two factors under study: toothpaste type (Colgate® Total Original, Oral B® 3D White Luxe Perfection, Curaprox® Black is White, and Signal® White Now) and brushing protocol (short- and long-term). Surface roughness was examined by atomic force microscopy (AFM), and color change (ΔE) was measured using the CIE L*a*b* system. Data were statistically analyzed using comparative parametric tests at a 5% significance level. In the short-term protocol, only the Signal® White Now toothpaste increased surface roughness (p = 0.038) compared to the Colgate® Total Original group. No significant differences (p > 0.05) were observed in surface roughness in the long-term protocol. Regarding color variation, no statistically significant differences (p > 0.05) were observed in either protocol. Overall, the whitening toothpastes did not affect enamel surface roughness or color, except for Signal® White Now, which caused increased roughness in the short-term protocol. However, all toothpastes induced a visual change in color.
Enhanced Solar Coronal Imaging: A GAN Approach with Fused Attention and Perceptual Quality Enhancement
Authors: Shang Zhenhong , Li Ruiyao
Published: May 2024

The activity of the solar corona has a significant impact on all aspects of human life. People typically use images obtained from astronomical telescopes to observe coronal activities, among which the Atmospheric Imaging Assembly (AIA) of the Solar Dynamics Observatory (SDO) is particularly widely used. However, due to resolution limitations, we have begun to study the application of generative adversarial network super-resolution techniques to enhance the image data quality for a clearer observation of the fine structures and dynamic processes in the solar atmosphere, which improves the prediction accuracy of solar activities. We aligned SDO/AIA images with images from the High-Resolution Coronal Imager (Hi-C) to create a dataset. This research proposes a new super-resolution method named SAFCSRGAN, which includes a spatial attention module that incorporates channel information, allowing the network model to better capture the corona’s features. A Charbonnier loss function was introduced to enhance the perceptual quality of the super-resolution images. Compared to the original method using ESRGAN, our method achieved an 11.9% increase in Peak Signal-to-Noise Ratio (PSNR) and a 4.8% increase in Structural Similarity (SSIM). Additionally, we introduced two perceptual image quality assessment metrics, the Natural Image Quality Evaluator (NIQE) and Learned Perceptual Image Patch Similarity (LPIPS), which improved perceptual quality by 10.8% and 1.3%, respectively. Finally, our experiments demonstrated that our improved model surpasses other models in restoring the details of coronal images.
Genes of Salmonella enterica Serovar Enteritidis Involved in Biofilm Formation
Authors: Lee Seulgi , Chen Jinru
Published: May 2024

Although biofilms contribute to bacterial tolerance to desiccation and survival in low-moisture foods, the molecular mechanisms underlying biofilm formation have not been fully understood. This study created a mutant library from Salmonella Enteritidis using mini-Tn10 transposon mutagenesis. The biofilm-forming potential of acquired mutants was assessed before the genomic DNA of the mutants that formed significantly (p ≤ 0.05) less biofilm mass than their wildtype parent strain was extracted for deep DNA sequencing. The gene of each mutant interrupted by mini-Tn10 insertion was identified by aligning obtained sequencing data with the reference Genbank sequences using a BLAST search. Sixty-four mutant colonies were selected, and five mutants that formed the least amount of biofilm mass compared to the wildtype parent strain were selected for sequencing analysis. The results of the BLAST search revealed that the gene interrupted by mini-Tn10 in each mutant is responsible for the biosynthesis of aldehyde dehydrogenase (EutE), cysteine desulfurase (SufS or SufE), a transporter protein, porin OmpL, and a ribbon–helix–helix protein from the CopG family, respectively. Knock-off mutant construction is a possible approach to verify the potential of the identified genes to serve as targets of antimicrobial intervention to control Salmonella colonization on low-moisture foods and in their production environment.
Scythian Jewelry Meshes and the Problem of Their Interpretation
Authors: Lifantii Oksana
Published: May 2024

This article explores the phenomenon of a specific type of personal adornment worn by members of the Scythian elite in the North Black Sea region in the second half of the 5th century and throughout the 4th century BCE. The discussion juxtaposes the records from 19th-century and early 20th-century excavations with contextual analyses of very recent discoveries from Ukraine, which shed significant new light on the appearance, production, and meaning of Scythian jewelry. The reconstruction of the shape of the jewelry type in question is greatly complicated by two factors: the lack of relevant depictions in the contemporary corpus of Scythian and Greco-Scythian figure scenes and misleading scholarly references to supposed analogies in a Roman-era mosaic, which became the chief reason for the misinterpretations of the ornament’s appearance. Composed of numerous gold or gilded silver tubes; beads; pendants; and, sometimes, “buttons,” this jewelry type is reconstructed in two gender-specific variants in this article: one mesh-like and the other with a cross-chest form. For over a hundred years, scholars have considered only the mesh variant to be the correct reconstruction. As a result, many costume reconstructions of this jewelry form in specialist research and museum displays alike are still proposed without a sufficient evidentiary base.
Analysis of Diffusion Characteristics and Influencing Factors of Particulate Matter in Ship Exhaust Plume in Arctic Environment Based on CFD
Authors: Zhu Yuanqing , Wan Qiqi , Hou Qichen , Feng Yongming , Yu Jia , Shi Jie , Xia Chong
Published: May 2024

The gradual opening of the Arctic shipping route has made navigation possible. However, the harm caused by ship exhaust emissions is increasingly severe. Therefore, it is necessary to study the diffusion characteristics of ship exhaust plumes during Arctic navigation. The study focuses on a merchant vessel as the subject of investigation, employing computational fluid dynamics (CFD) simulation techniques to analyze the diffusion characteristics of particulate matter (PM) within ship exhaust plumes under Arctic environmental conditions. The diffusion law of ship exhaust plume PM is clarified, and the influence of three factors, synthetic wind speed, yaw angle and chimney angle, on the PM diffusion is analyzed. It was found that after the PM was discharged from the chimney, the majority of the PM dispersed directly backward along with the external flow field, while a minor fraction lingered at the stern of the ship for an extended period before eventually diffusing backward. Among them, 1235 particles were captured within a range of 200 m from the stern, with a capture rate of 0.6%. When the synthetic wind shows a yaw angle, the capture rate of PM in the interval increases rapidly with the increase of yaw angle, while other factors have less influence on the capture rate of PM. This study provides foundational guidance for predicting PM diffusion from ship exhaust plumes in Arctic environments, thereby enabling more effective strategies for managing such emissions.
Activity of NAD(P)H-Oxidoreductases in Ovarian Cancer
Authors: Fedorova Maria V. , Voznesensky Vladimir I. , Sosnova Elena A. , Proskurnina Elena V.
Published: May 2024

Reactive oxygen species (ROS) play an important and controversial role in carcinogenesis. Microsomal redox chains containing NADH- and NADPH-dependent oxidoreductases are among the main sites of intracellular ROS synthesis, but their role in the oxidative balance has not been fully studied. Here, we studied the activity of cytochrome b5 reductase (CYB5R) and cytochrome P450 reductase (CYPOR) in ovarian cancer tissues and cells isolated from peritoneal fluid, along with the antioxidant capacity of peritoneal fluid. We used the developed a chemiluminescence assay based on stimulation with NADH and NADPH, which reflects the activity of CYB5R and CYPOR, respectively. The activity of CYB5R and CYPOR was significantly higher in moderately and poorly differentiated ovarian adenocarcinomas compared with well-differentiated adenocarcinomas and cystadenomas. For the chemotherapy-resistant tumors, the activity of tissue CYB5R and CYPOR was lower compared to the non-resistant tumors. In the peritoneal fluid, the antioxidant capacity significantly increased in this series, benign tumors < well-differentiated < moderately and poorly differentiated adenocarcinomas, so the antioxidant excess was observed for moderately and poorly differentiated adenocarcinomas. The antioxidant capacity of peritoneal fluid and the activity of CYB5R and CYPOR of cells isolated from peritoneal fluid were characterized by a direct moderate correlation for moderately and poorly differentiated adenocarcinomas. These results indicate the significant role of NAD(P)H oxidoreductases and the antioxidant potential of peritoneal fluid in cancer biochemistry. The parameters studied are useful for diagnostics and prognostics. The developed assay can be used to analyze CYB5R and CYPOR activity in other tissues and cells.
Exploring the Association between Cathepsin B and Parkinson’s Disease
Authors: Lu Changhao , Cai Xinyi , Zhi Shilin , Wen Xiaofen , Shen Jiaxin , Ercoli Tommaso , Simula Elena Rita , Masala Carla , Sechi Leonardo A. , Solla Paolo
Published: May 2024

Objective: The aim of this study is to investigate the association between Cathepsin B and Parkinson’s Disease (PD), with a particular focus on determining the role of N-acetylaspartate as a potential mediator. Methods: We used summary-level data from Genome-Wide Association Studies (GWAS) for a two-sample Mendelian randomization (MR) analysis, exploring the association between Cathepsin B (3301 cases) and PD (4681 cases). A sequential two-step MR approach was applied (8148 cases) to study the role of N-acetylaspartate. Results: The MR analysis yielded that genetically predicted elevated Cathepsin B levels correlated with a reduced risk of developing PD (p = 0.0133, OR: 0.9171, 95% CI: 0.8563–0.9821). On the other hand, the analysis provided insufficient evidence to determine that PD affected Cathepsin B levels (p = 0.8567, OR: 1.0035, 95% CI: 0.9666–1.0418). The estimated effect of N-acetylaspartate in this process was 7.52% (95% CI = −3.65% to 18.69%). Conclusions: This study suggested that elevated Cathepsin B levels decreased the risk of developing PD, with the mediation effect of N-acetylaspartate. Further research is needed to better understand this relationship.
The Comparison of Lifestyles, Mental Risks, and Physical Indices among Individuals with Ultra-High Risk of Psychosis, Patients with Schizophrenia, and the General Public
Authors: Tsai Ching-Lun , Chu Chi-Ming , Lane Hsien-Yuan , Chen Shiah-Lian , Tu Cheng-Hao , Ma Wei-Fen
Published: May 2024

(1) Background: Early interventions may effectively reduce the risk of mental disorders in individuals with ultra-high risk. Specifying the health needs of individuals with ultra-high risk is crucial before the implementation of successful early intervention. This study aimed to explore the differences in lifestyles, mental risks, and physical indices among individuals with ultra-high risk, patients with schizophrenia, and healthy subjects. (2) Methods: A cross-section design applying seven questionnaires with physical examinations for 144 participants aged 13–45 years old was conducted in this study. The questionnaires included one about personal data, four on mental risks, and two for lifestyles. (3) Results: The individuals with ultra-high risk scored similarly in many dimensions as the patients with schizophrenia, but they displayed lower positive symptoms, lower negative symptoms, lower prodromal symptoms, higher interpersonal deficits, lower nutrition intake, and higher levels of exercise than the patients with schizophrenia. Female individuals with ultra-high risk had lower self-esteem, higher positive symptoms, lower nutrition intake, and higher exercise levels than male ones. (4) Conclusions: The study pinpointed specific health needs with interpersonal deficits, nutrition intake, and physical activity for the individuals with ultra-high risk. Future interventions targeted on improving social function, dietary pattern, and exercise will be beneficial.
Progressive Failure Mechanism of Shield Tunnel Face in Complex Urban Geological Environment
Authors: Huang Qingfei , Han Kaihang
Published: May 2024

The construction of multiple tunnels across inland rivers has had a significant influence on the improvement of the transportation infrastructure. The technology for constructing tunnels is progressing towards the development of larger cross-sections, longer distances, and the ability to withstand high hydraulic pressure in complex hydrogeological conditions, including high-permeability strata. In order to ensure the face stability of shield tunnels under high hydraulic pressure that crosses a fault fracture zone, it is necessary to study the progressive failure mechanism of shield tunnel faces induced by high hydraulic pressure seepage. This paper employs finite element numerical simulation software to methodically examine the variation in the characteristics of the water seepage field, limiting support force, and face stability failure mode of shield tunnels passing through fault fracture zones with high hydraulic pressure under varying fault fracture width zones. The results show that the formation hydraulic gradient will progressively widen when the tunnel face is located within the undisturbed rock mass and is advanced towards the area of fault fracture. This will raise the likelihood of instability in the shield tunnel and progressively raise the limiting support force on the tunnel face. Moreover, as the tunnel face nears the region of fault fracture within the undisturbed rock mass, the damage range increases gradually. In addition, due to the increase in seepage force, the angle between the failure area and the horizontal plane becomes more and more gentle. On the contrary, as the tunnel’s face moves closer to the undisturbed rock mass from the region of the fault fracture, the damage range gradually decreases, and the dip angle between the damage area and the horizontal plane becomes steeper and steeper due to the decreasing seepage force in the process. The study findings presented in this work are highly significant, both theoretically and practically, for the design and management of safety.
Immuno-Hematologic Complexity of ABO-Incompatible Allogeneic HSC Transplantation
Authors: Matteocci Antonella , Pierelli Luca
Published: May 2024

ABO incompatibility is not considered a contraindication for hematopoietic stem cell transplantation (HSCT). Approximately 30% of transplants from related donors and up to 50% of transplants from unrelated donors are ABO incompatible. Immuno-hematologic investigations allow to estimate donor/recipient ABO mismatch and anti-A/B isohemagglutinin (IHA) titration in the pre-HSCT phase. Immediate hemolysis or delayed complications (passenger lymphocyte syndrome and pure red cell aplasia) can occur post HSCT. Some preventive measures take into consideration either decision-making algorithms based on the recipient’s IHA titration or clinical protocols for the removal/reduction of IHAs through plasma exchange or immunoadsorption procedures. Product manipulation through red blood cell (RBC) and/or plasma depletion can also be taken into account. Currently, the best approach in the management of ABO-incompatible transplant is not defined in expert consensus documents or with solid evidence. In addition, the methods for IHA titration are not standardized. A transfusion strategy must consider both the donor’s and recipient’s blood group systems until the RBC engraftment catches on and ABO conversion (forward and reverse typing) is confirmed on two consecutive and independent samples. Therefore, ABO incompatibility in HSCT represents a demanding immuno-hematologic challenge and requires all necessary preventive measures, including the appropriate selection of ABO blood components for transfusion.
Correction: Zhao et al. Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN). Cells 2020, 9, 559
Authors: Zhao Yin , Lei Yuan , He Shi-Wei , Li Ying-Qin , Wang Ya-Qin , Hong Xiao-Hong , Liang Ye-Lin , Li Jun-Yan , Chen Yang , Luo Wei-Jie , Zhang Pan-Pan , Yang Xiao-Jing , He Qing-Mei , Ma Jun , Liu Na , Tang Ling-Long
Published: May 2024

In the original publication [...]
Synthesis, Spectral Characteristics, Sensing Properties and Microbiological Activity of New Water-Soluble 4-Sulfo-1,8-naphthalimides
Authors: Said Awad I. , Staneva Desislava , Vasileva-Tonkova Evgenia , Grozdanov Petar , Nikolova Ivanka , Stoyanova Radostina , Jordanova Albena , Grabchev Ivo
Published: May 2024

A new water-soluble polyamidoamine (PAMAM) dendrimer modified with 4-sulfo-1,8-naphthalimide (DSNI) and its monomeric structural analogue (MSDI) were synthesized. Their photophysical properties were investigated in organic solvents of different polarities and aqueous solutions. The effect of pH on fluorescence intensity was determined. It was found that the dendrimer emits blue fluorescence in an acidic medium, which is quenched in an alkaline environment. This phenomenon is due to the possibility of suppression of nonradiative photoinduced electron transfer in acidic media. The influence of different metal ions (Cu2+, Pb2+, Sn2+, Sr2+, Mg2+, Ba2+, Co2+, Hg2+, Zn2+, Ni2+, Fe3+, Al3+) and anions (CN−, S2−, S2O52−, HPO42−, H2PO4−, F−, CH3COO−, NO2−, CO32−, SO42−) on the intensity of the emitted fluorescence was studied. Quenching was only found in the presence of Cu2+. This makes the dendrimer suitable for determining copper ions in water solutions in the presence of other metal ions and anions. Additionally, DSNI was used as a ligand to obtain a stable copper complex, the structure of which was investigated by electron paramagnetic resonance (EPR), infrared spectrum, and elemental analysis. Two copper ions were found to form a complex with one dendrimer. The in vitro microbiological activity of the new compounds against bacteria Pseudomonas aeruginosa and two viruses HRSV-2 and HAdV-5 was investigated. With a view to obtaining antibacterial and anti-viral textiles, cotton fabrics were treated with the three compounds, and then their activity against the same microbial strains was investigated. It was found that the microbiological activity was preserved after the application of the new compounds to the cotton fabrics.
Adverse Skeletal Muscle Adaptations in Individuals Born Preterm—A Comprehensive Review
Authors: Dobson Nick L. , Levitt Danielle E. , Luk Hui Ying , Vellers Heather L.
Published: May 2024

Infants born preterm face an increased risk of deleterious effects on lung and brain health that can significantly alter long-term function and quality of life and even lead to death. Moreover, preterm birth is also associated with a heightened risk of diabetes and obesity later in life, leading to an increased risk of all-cause mortality in young adults born prematurely. While these preterm-birth-related conditions have been well characterized, less is known about the long-term effects of preterm birth on skeletal muscle health and, specifically, an individual’s skeletal muscle hypertrophic potential later in life. In this review, we discuss how a confluence of potentially interrelated and self-perpetuating elements associated with preterm birth might converge on anabolic and catabolic pathways to ultimately blunt skeletal muscle hypertrophy, identifying critical areas for future research.
Photocatalytic Activity and Antibacterial Properties of Mixed-Phase Oxides on Titanium Implant Alloy Substrates
Authors: Johnson Haden A. , Donaho Darby , Ali Aya , Parekh Amisha , Williamson Randall S. , Marquart Mary E. , Bumgardner Joel D. , Janorkar Amol V. , Roach Michael D.
Published: May 2024

Titanium alloys are commonly used for implants, but the naturally forming oxides are bioinert and not ideal for bacterial resistance or osseointegration. Anodization processes are a modification technique that can crystallize the oxides, alter oxide surface topography, and introduce beneficial chemistries. Crystalline titanium oxides are known to exhibit photocatalytic activity (PCA) under UVA light. Anodization was used to create mixed-phase oxides on six titanium alloys including commercially pure titanium (CPTi), Ti-6Al-4V (TAV), Ti-6Al-7Nb (TAN), two forms of Ti-15Mo (TiMo-β and TiMo-αβ), and Ti-35Nb-7Zr-5Ta (TNZT). Combined EDS and XPS analyses showed uptake of the electrolyte and substrate alloying elements into the oxides. The relative oxide PCA was measured using methylene blue degradation assays. CPTi and TAN oxides exhibited increased PCA compared to other alloys. Combined XRD and EBSD oxide phase analyses revealed an unfavorable arrangement of anatase and rutile phases near the outermost surfaces, which may have reduced PCA for other oxides. The relative Staphylococcus aureus attachment to each oxide was also assessed. The CPTi and TiMo-αβ oxides showed significantly reduced S. aureus attachment after 1 h of UVA compared to un-anodized CPTi. Cell culture results verified that the UVA irradiation did not negatively influence the MC3T3-E1 attachment or proliferation on the mixed-phase oxides.
Enhancing Carbon Fiber Fabrics with ALD AlxOy Coatings: An Investigation of Thickness Effects on Weight, Morphology, Coloration, and Thermal Properties
Authors: Dias Vanessa , Galvão Nierlly , Miranda Felipe , Fraga Mariana , Petraconi Gilberto , Maciel Homero , Pessoa Rodrigo
Published: May 2024

This study explores the impact of non-stoichiometric aluminum oxide (AlxOy) coatings applied via thermal atomic layer deposition (ALD) on carbon fiber fabrics (CFFs), emphasizing volume per cycle, FESEM analyses, color transitions, and thermal stability enhancements. Using trimethylaluminum and water at 100 °C, AlxOy was deposited across a range of 1000 to 5000 ALD cycles, with film thicknesses extending up to 500 nm. This notable increase in the volume of material deposited per cycle was observed for the 3D CFFs, highlighting ALD’s capability to coat complex structures effectively. FESEM analyses revealed the morphological evolution of CFF surfaces post-coating, showing a transition from individual grains to a dense, continuous layer as ALD cycles increased. This morphological transformation led to significant color shifts from green to red to blue, attributed to structural coloration effects arising from variations in film thickness and surface morphology. Thermogravimetric analyses (TGA and dTG) indicated that the AlxOy coatings enhanced the thermal stability of CFFs, with a postponement in degradation onset observed in samples subjected to more ALD cycles. In essence, this research highlights the nuanced relationship between ALD processing parameters and their collective influence on both the aesthetic and functional properties of CFFs. This study illustrates ALD’s potential in customizing CFFs for applications requiring specific color and thermal resilience, balancing the discussion between the surface morphological changes and their implications for color and thermal behavior.
Highly Stable Hybrid Pigments Prepared from Organic Chromophores and Fluorinated Hydrotalcites
Authors: Hernández Magali , Felipe Carlos , Guzmán-Vargas Ariel , Rivera José Luis , Lima Enrique
Published: May 2024

Structural hydroxide groups in layered magnesium–aluminum double hydroxides were partially replaced by fluoride ions. Fluorinated and fluorine-free materials were used as hosts for two dyes, carminic acid and hydroxyl naphthol blue, resulting in a hybrid pigment color palette. The pigments were produced by two ways, either incorporating chromophore during the synthesis of the layered double hydroxide or in a post-synthesis step through the memory effect of the LDHs. Additionally, the pigments were protected with a magnesium hydroxide phase to prevent the color from fading over time. The pigments were stable for periods as long as 10 years. The color properties of the pigments were significantly influenced by the host of dye since the presence of fluorine directly influences the acid–base properties of the layered double hydroxides. The pigments conferred their color to white cream in the preparation of colored creams. The colored creams acquired the color of the layered pigment.
One Hundred and Thirty-Five Years of Ornithology in Bulgaria: The Role of the National Museum of Natural History at the Bulgarian Academy of Sciences in the Development of Ornithology in Bulgaria—Representatives, Collections and Achievements
Authors: Boev Zlatozar
Published: May 2024

For the first time, an attempt has been made to present, chronologically and in a systematized form, the development of ornithological studies at the National Museum of Natural History in Sofia (Bulgaria) from its foundation in the last decades of the 19th century to the present day. This 135-year period (1889–2024) includes the work of 12 curators of the ornithological collections. Their major contributions and most-significant ornithological publications are also presented.
Indigestible Trichobezoar Mimicking Inflammatory Bowel Disease: A Case Report and a Literature Review
Authors: Bellini Tommaso , Franzone Daniele , Pezzotta Federico , Andreottola Valentina , Lionetti Barbara , Formigoni Clelia , Fueri Elena , Gandullia Paolo , Piccotti Emanuela , Mattioli Girolamo
Published: May 2024

A 15-year-old girl was admitted to the Pediatric Emergency Department due to abdominal discomfort, anorexia, diarrhea, emesis, and weight loss. An inflammatory bowel disease diagnosis was suspected and a complete endoscopic investigation was deemed necessary. Initially, only colonoscopy with ileoscopy was performed, with evidence of widespread ileal ulcers, whereas a subsequent esophagogastroduodenoscopy revealed a huge trichobezoar that was further surgically removed. Trichobezoars are intraluminal conglomerates composed of ingested hair and are typically associated with underlying psychiatric disorders. Bezoars can be asymptomatic or present with various gastrointestinal symptoms, mimicking, among other conditions, inflammatory bowel disease. They may extend through the pylorus into the jejunum leading to Rapunzel Syndrome, which may cause intestinal obstruction. The treatment of trichobezoar depends on its location and volume. An endoscopic approach is possible for small-sized trichobezoars, but to avoid bezoar tail migration along the intestine, causing obstruction, conventional laparotomy is the only valid treatment for patients with Rapunzel Syndrome. Due to the increasing incidence of psychiatric disorders in pediatric age during the SARS-CoV-2 pandemic and their relationship with trichobezoars, an increase in cases of trichobezoars was observed. Thus, interdisciplinary collaboration between psychiatrists, pediatricians, and surgeons is crucial not only during the acute phase but also for long-term management and prevention of recurrence.
Improving Election Integrity: Blockchain and Byzantine Generals Problem Theory in Vote Systems
Authors: Mwansa Patrick , Kabaso Boniface
Published: May 2024

In the digital age, maintaining election integrity is critical, especially in Africa, where the security of electronic elections is often questioned. This study presents a blockchain-based vote counting and validation (BBVV) system developed using a mixed methods approach that combines stakeholder questionnaires to capture system specification and randomized historical election data analysis, following the Design Science Research strategy. Using the theory of the Byzantine General Problem, the BBVV protocol is proposed, which provides an accurate local count of votes at polling stations before national aggregation. The system was tested with randomized historical election data on the Algorand blockchain TestNet and confirmed that a local consensus on the vote count could be reached before it is added to the national tally on the blockchain. Our results show that in the cases where consensus was reached, this was the instance in only about 5% of the voting scenarios, with only 10% of the total vote being considered valid due to the strict consensus requirements. In addition, significant discrepancies were found between officials, with no consensus reached in 95% of cases which was due to the rogue values generated by a randomized dataset. The performance of the BBVV system was evaluated using transaction metrics, saturation, throughput, traffic, and latency to assess its efficiency, scalability, and reliability. The results suggest that blockchain technology can significantly improve the integrity of elections by ensuring a transparent, secure, and accurate vote-counting process. Future work will focus on improving the adaptability and scalability of the BBVV system for different electoral situations.
Emerging Trends and Challenges in Pink Hydrogen Research
Authors: Fernández-Arias Pablo , Antón-Sancho Álvaro , Lampropoulos Georgios , Vergara Diego
Published: May 2024

Pink hydrogen is the name given to the technological variant of hydrogen generation from nuclear energy. This technology aims to address the environmental challenges associated with conventional hydrogen production, positioning itself as a more sustainable and eco-efficient alternative, while offering a viable alternative to nuclear power as a source of electricity generation. The present research analyzes the landscape of pink hydrogen research, an innovative strand of renewable energy research. The methodology included a comprehensive search of scientific databases, which revealed a steady increase in the number of publications in recent years. This increase suggests a growing interest in and recognition of the importance of pink hydrogen in the transition to cleaner and more sustainable energy sources. The results reflect the immaturity of this technology, where there is no single international strategy and where there is some diversity of research topic areas, as well as a small number of relevant topics. It is estimated that the future development of Gen IV nuclear reactors, as well as Small Modular Reactor (SMR) designs, will also favor the implementation of pink hydrogen.
An Open-Source Supervisory Control and Data Acquisition Architecture for Photovoltaic System Monitoring Using ESP32, Banana Pi M4, and Node-RED
Authors: He Wei , Baig Mirza Jabbar Aziz , Iqbal Mohammad Tariq
Published: May 2024

To overcome the issues of the existing properties and the non-configurable supervisory control and data acquisition (SCADA) architecture, this paper proposes an IoT-centered open-source SCADA system for monitoring photovoltaic (PV) systems. The system consists of three voltage sensors and three current sensors for data accumulation from the PV panel, the battery, and the load. As a part of the system design, a relay is used that controls the load remotely. An ESP32-E microcontroller transmits the collected data to a Banana Pi M4 Berry (BPI-M4 Berry) through the Message Queuing Telemetry Transport (MQTT) protocol over a privately established communication channel using Wi-Fi. The ESP32-E is configured as the MQTT publisher and the BPI-M4 Berry serves as the MQTT broker. Locally installed on the BPI-M4 Berry, the Node-RED platform creates highly customizable dashboards as human–machine interfaces (HMIs) to achieve real-time monitoring of the PV system. The proposed system was successfully tested to collect the PV system voltage/current/power data and to control the load in a supervisory way under a laboratory setup. The complete SCADA architecture details and test results for the PV system data during the total eclipse on 8 April 2024 and another day are presented in this paper.
Piezoelectric Sensors Pressed by Human Footsteps for Energy Harvesting
Authors: Selim Kyrillos K. , Smaili Idris H. , Yehia Hossam M. , Ahmed M. M. R. , Saleeb Demyana A.
Published: May 2024

Human footsteps are a sustainable energy source that is derived from kinetic energy. As a result, in this study, piezoelectric sensors placed beneath floor tiles were excited by human footsteps to provide practical electrical energy. A simple rectifying circuit with a filter was used to capture electrical power. The floor tile is 455 mm in length and 405 mm in width. Two light-emitted diodes were lit up as the actual load by utilising electrical energy obtained from the kinetic energy generated by human footsteps. The greatest attainable power that could be extracted from the suggested floor tile was 249.6 milliwatts, with an approximate cost of $10.2.
Arguments for a Community-Based Approach to Geothermal Energy Development
Authors: Kurek Katarzyna A. , van Ophem Johan , Strojny Jacek
Published: May 2024

This paper investigates the theoretical foundation for developing renewable geothermal resources locally. For this reason, we pay attention to the role of communities in geothermal development. We derive it from the integral characteristics of geothermal energy next to the shift in the energy transition policies to focus on managing green resources locally. This study presents arguments for a framework that approaches geothermal resources as an endogenous factor of community development. To analyse it, we create a model that explains the local economic characteristics of geothermal exploitation beyond its geological conditions. It aims to conceptualise a community-based geothermal development standard referring to the endogeneity principle. Geothermal energy is given attention since the characteristics of this resource determine its use locally. This induces the internalisation of labour and technology in the local economic system, a specific condition for local geothermal projects where a community remains a prime beneficiary. We argue that the role of communities in geothermal exploitation is pivotal in the process of green growth for further expansion of geothermal energy use.
Effects of Biochar on Soil Inorganic Phosphorus Components, Available Phosphorus, Enzyme Activities Related to Phosphorus Cycle, Microbial Functional Genes, and Seedling Growth of Populus euphratica under Different Water Conditions
Authors: Fan Yuxian , Chen Yudong , Lv Guanghui
Published: May 2024

Cow dung is a kind of high quality and renewable biological resource. Biochar made from cow dung can be used as a soil amendment to improve soil nutrient status. The relationship between soil water and phosphorus is very close, and the water status determines the form, content, and availability of phosphorus. In order to investigate the effects of biochar on soil inorganic phosphorus components, available phosphorus, enzyme activities related to the phosphorus cycle, microbial functional genes, and seedling growth under different soil water conditions were investigated. Field experiments were carried out by setting different water conditions (30%, 60%, and 100%) and biochar addition (0 t hm−2, 2.63 t hm−2, 5.26 t hm−2, and 7.89 t hm−2). The results showed that applying biochar significantly increased the soil’s accessible phosphorus content and the phosphorus content in both the aboveground and subsurface parts of P. euphratica seedlings. This is mainly attributable to biochar’s direct and indirect effects on soil properties. Because biochar is naturally alkaline, it raises soil pH and reduces acid phosphatase activity in the soil around P. euphratica seedlings in the rhizosphere. Perhaps the alkaline phosphatase level first showed an upward trend due to the combined impacts of water and biochar, and then it started to decline when the biochar addition was increased. Soil phosphorus functional genes phoC, phoD, gcd, and pqqc had an increase in copy number with biochar addition but not without treatment. Indirectly, the biochar treatment increased the soil’s phosphorus availability by increasing the population of the phosphate-solubilizing bacteria Fusarium and Sphingomonas. Soil phosphorus availability is positively affected by biochar under various water conditions. This impact is due to chemical and microbiological mechanisms.
Phenology, Yield and Nut Traits Evaluation of Twelve European Hazelnut Cultivars Grown in Central Italy
Authors: Pacchiarelli Alberto , Lupo Michela , Ferrucci Andrea , Giovanelli Francesco , Priori Simone , Pica Aniello Luca , Silvestri Cristian , Cristofori Valerio
Published: May 2024

European hazelnut (Corylus avellana L.) cultivation has grown worldwide in recent years, even though the world’s production is still fulfilled by a few dozen cultivars well adapted to the local environments of their selection. After Turkey, Italy is the second largest producer of hazelnuts, and the province of Viterbo, in central Italy, is recognized as one of the most suitable districts for hazelnut cultivation. The production in this area relies almost entirely on local cultivar ‘Tonda Gentile Romana’, whereas cultivar ‘Nocchione’ is used as the main pollinizer. More recently, cultivar ‘Tonda di Giffoni’ has been introduced in new local plantations. Cultivation of many cultivars in different areas is of fundamental importance to test their adaptability to different environmental conditions, a need currently accentuated by ongoing climate change. With this aim, a European hazelnut collection field was established in 2000 in Caprarola municipality (Viterbo province), where plants of twelve hazelnut cultivars were observed over four growing seasons for their phenological, agronomic and nut traits. The cultivars studied, namely ‘Barcelona’, ‘Camponica’, ‘Ennis’, ‘Merveille de Bollwiller’, ‘Negret’, ‘Nocchione’, ‘Riccia di Talanico’, ‘San Giovanni’, ‘Tombul’, ‘Tonda di Giffoni’, ‘Tonda Gentile’ and ‘Tonda Gentile Romana’, showed a high diversity in their phenological behaviour, yield efficiency and nut and kernel traits. Cultivars ‘Negret’, ‘Tombul’ and ‘Tonda Gentile’, with poor yields over the years of research, do not seem suitable to be cultivated as main cultivars in the studied environment, contrary to ‘Camponica’ and ‘San Giovanni’, which produced abundantly, reaching a total of almost 30 and 25 kg plant—1 of in–shell hazelnuts, respectively. Cultivars ‘Tonda Gentile Romana’ and ‘Nocchione’ confirmed their yield consistency, whereas ‘Ennis’, ‘Barcelona’ and ‘Tombul’ seem suitable to be introduced as pollinizers thanks to their male blooming overlapping with the female blooming of the main cultivar ‘Tonda Gentile Romana’. Cultivar ‘Tonda di Giffoni’ did not perform well in the studied environment, despite being recognized as one of the highest-yield cultivars.
Methane Production Reduced by Lignin Derivatives in Pulping Wastewater: Inhibition of Free Hydrolase
Authors: Lei Jinxu , Xu Zhihong , Chen Yong , Yu Guo , Liu Zexiang , Wang Shuangfei , Zhang Jian , Li Kelin , Xie Li
Published: May 2024

The lignin derivatives generated during pulping might be responsible for the suboptimal performance of anaerobic reactors during the treatment of pulping wastewater. However, the exact mechanisms by which these derivatives exert influence remain unclear. This study investigated the influence of lignin derivatives, simulated using humic acids (HAs), in anaerobic granular sludge (AnGS). Compared to the enzymes present during floc-bonding and granule-bonding, the HAs impeded the conversion of unhydrolyzed substrates into methane and caused considerable inactivation of free enzymes. Simultaneously, the HAs suppressed agglomeration and weakened the strength of the AnGS. Furthermore, calcium ions helped maintain the integrity of the sludge structure. Therefore, the inhibition of extracellular enzymes using lignin derivatives delays the methanation of unhydrolyzed substrates, resulting in a reduced biomass within AnGS reactors owing to sludge disintegration and biomass loss. This study serves as a reference for investigating the persistent risks originating from lignin derivatives associated with using anaerobic granular-sludge bed reactors to treat pulping wastewater.
The Effect of Extraction by Pressing at Different Temperatures on Sesame Oil Quality Characteristics
Authors: Piravi-Vanak Zahra , Dadazadeh Abdolah , Azadmard-Damirchi Sodeif , Torbati Mohammadali , Martinez Fleming
Published: May 2024

Sesame oil has been widely used in the daily diet due to its high nutritional value. Sesame oil is extracted at industrial scales and also in small scale by cold pressing at different temperatures. In this research, sesame oil was extracted by pressing at four temperatures, namely, 30 (control sample), 60, 90 and 120 °C, to evaluate its effects on the quality of extracted oils. Oil extraction yields were increased from 38 to 51% by increasing the pressing temperature. The highest amount of peroxide and acid values were related to the oil extracted at 120 °C. Tocopherols and total phenol content were reduced by the increasing the pressing temperature, and the highest amounts of these bioactive components were related to the control sample. The results of the fatty acids profile showed that the composition of oils extracted at different temperatures did not differ significantly (p > 0.05). The results of the present study give a clear picture about the effects of different pressing temperatures on the sesame oil quality and extraction yield, and can be useful in the extraction unit optimization.
Characterization of Lipid Extracts from Different Colors of Peach Palm Fruits—Red, Yellow, Green, and White—Obtained through Ultrasound-Assisted Green Extraction
Authors: Santos Mayara Priscila Lima dos , Santos Orquídea Vasconcelos dos , Conceição Leyvison Rafael Vieira da , Teixeira-Costa Barbara Elisabeth , Lourenço Lúcia de Fátima Henriques , Sousa Consuelo Lucia Lima de
Published: May 2024

This study represents a pioneering investigation and comparative analysis of lipid extracts from four different colors of peach palm (Bactris gasipaes Kunt) fruits—red, yellow, green, and white—by employing a green method based on ethanolic ultrasound-assisted extraction. This study examined the extraction yield, physico-chemical-quality attributes, chromatographic profiles (GC), color measurements, total carotenoid content, differential thermogravimetry (TG/DTA), and infrared spectroscopy (FTIR). The obtained lipid extracts displayed a high quality, considering the physico-chemical parameters of the Codex Alimentarius, and a fatty acids profile characterized by unsaturated fatty acids, notably omegas (ω-3, ω-6, and ω-9). The indices of atherogenicity (A.I.), thrombogenicity (I.T.), and hypocholesterolemic and hypercholesterolemic ratios revealed superior outcomes for the red peach palm lipid extract (approximately 0.35, 0.52, and 2.75, respectively), along with higher levels of β-carotene (748.36 µg of β-carotene per 100 g−1 of lipid extract) compared to the yellow, green, and white counterparts. Consequently, this research successfully demonstrates the efficacy of using a green extraction method in preserving the lipid’s quality, which can display cardiovascular functionality and thermal stability. These findings underscore the considerable potential of peach palm lipid extract as a valuable raw material for diverse industrial applications across various sectors. The results support its utilization in the production of functional food products and nutraceuticals due to its favorable fatty acid composition, potent antioxidant properties exhibited by its high β-carotene content, and notable cardiovascular functionality indices.
Acerola Cherry and Rosemary Extracts Improve Color and Delay Lipid Oxidation in Previously Frozen Beef
Authors: Van Buren Jessie B. , Epperson Brooklyn , Jepsen Sierra , Heimbuch Mikayla , Oliver Kayleen , Nasados James , Bass Phillip D. , Colle Michael J.
Published: May 2024

Extending the shelf life of exported beef could increase international demand and producer profits. The objective was to evaluate the effects of topically applying combinations of acerola cherry powder and rosemary extract on the shelf life of frozen–thawed bone-in beef short rib and chuck roll steaks. Chuck rolls (IMPS 116A; N = 9) and bone-in short ribs (IMPS 123A; N = 18) were aged (7 d; 0 °C), frozen (30 d; −20 °C), and thawed (60–72 h; 0 °C). Steaks measuring 1.02 cm thick were treated and subjected to a 4 d retail display. Steaks were left untreated (control) or sprayed topically with acerola cherry powder (0.05%; A), rosemary extract (0.10%; R), or a combination (M1 = 0.05% A + 0.1% R; M2 = 0.1% A + 0.1% R; M3 = 0.05% A + 0.2% R; M4 = 0.1% A + 0.2% R). Chuck roll M2- and M4-treated steaks were redder than the control steaks on days 3 and 4 (p = 0.008), and antioxidant-treated steaks had less lipid oxidation on day 4 than the control steaks (p = 0.021). Bone marrow samples treated with R, M3, and M4 were redder than the control on days 1–3 (p = 0.014), and bone marrow treated with M3 was subjectively redder compared to the control on days 0 and 1 (p = 0.033). Topical antioxidants improve the redness and delay the oxidation of frozen–thawed beef.