bluuebunny/crossref_metadata_2025 huggingface dataset:
EVALUASI KINERJA INSTALASI PENGOLAHAN AIR LIMBAH DOMESTIK (STUDI KASUS: IPAL DOMESTIK WADUK â€œXâ€, JAKARTA)
Authors: Lestari Devita Satya
Published: December 2020

Aktivitas penduduk di Jakarta sangat berpengaruh terhadap jenis limbah yang dihasilkan, salah satunya berupa air limbah domestik yang berasal dari aktivitas rumah tangga. Tujuan dari penelitian ini adalah untuk mengetahui kualitas efluen IPAL dan efisiensi IPAL domestik di Waduk â€œXâ€, Jakarta. Penelitian ini menggunakan metode kuantitatif dengan melakukan analisis sampel air pengolahan limbah domestik dengan parameter TSS, BOD, COD, minyak lemak, pH, amonia total dan total koli. Adapun pengambilan sampel, dilakukan sebanyak 2 kali dalam satu tahun. Kemudian hasil analisis dibandingkan dengan baku mutu air limbah domestik berdasarkan Peraturan Menteri Lingkungan Hidup dan Kehutanan Nomor 68 Tahun 2016 dan dilakukan perhitungan persen efisiensi pengolahan. Berdasarkan hasil penelitian disimpulkan bahwa IPAL domestik di Waduk â€œXâ€, Jakarta, dapat menurunkan kandungan TSS, BOD, COD, amonia total, minyak dan lemak serta pH sehingga memenuhi baku mutu, kecuali parameter total koli. Kemudian berdasarkan hasil perhitungan persen efisiensi pengolahan disimpulkan bahwa IPAL domestik di Waduk â€œXâ€, Jakarta, telah cukup efisien hingga sangat efisien dalam mengolah limbah TSS, BOD, COD, amonia total, minyak dan lemak.Kata kunci: Air limbah domestik, instalasi pengolahan air limbah, metode MBBR, baku mutu, efisiensi pengolahan
Lo spasimo di Palermo fra crisi e memoria
Authors: Gallo Cinzia
Published: December 2020

Lo Spasimo di Palermo è esempio di una crisi che ha ripercussioni
nella forma espressiva: da una parte, emerge la consapevolezza che «sul
ciglio dell’abisso la parola si raggela, si fa […] simbolo sfuggente», dall’altra
il romanzo appare un «genere scaduto, corrotto, impraticabile». Il conflitto
generazionale fra Chino e Mauro rientra pure in quest’ambito. Da qui
derivano varie soluzioni che portano al «poema narrativo» di Consolo
e testimoniano il disorientamento prevalente: accumuli paratattici,
metafore, figure retoriche, figure del discorso. Le suggestioni pittoriche
trovano il loro centro nello Spasimo di Sicilia di Raffaello, simbolo di una
sofferenza che da Palermo arriva alla Sicilia e a tutto il mondo, mentre gli
spazi hanno una grande importanza e mostrano la perdita della memoria
storica, responsabile della crisi.
Gerente de Salud en SES Tocantins: Evaluación de conocimientos y competencias
Authors: Barbosa César Martins , Pinto Isabela Cardoso de Matos
Published: December 2020

Se trata de un estudio descriptivo exploratorio, cuyo principal objetivo es caracterizar el perfil del gestor de salud, a través del mapeo de conocimientos y habilidades. En cuanto al conocimiento y aplicación de las leyes que rigen el proceso de licitación, el 93% de los encuestados conoce las leyes de licitación y las utiliza en su trabajo diario, mientras que el 6,7% tiene conocimientos sobre el tema, sin embargo, no utilizarlo en el desempeño de sus tareas. En cuanto a las bases legales del SUS, solo es conocido por el 73,3% de la muestra. Los datos muestran que el 80% de los profesionales conocen la LRF. Sobre LOA, solo el 40% de los profesionales entrevistados afirman conocerlo. Cuando se preguntó a los sujetos sobre su conocimiento sobre PPA, solo el 60% dijo que conocía el instrumento. SIOPS es conocido solo por el 40% del grupo. El 86,7% de los profesionales conocen el RAG. El PPI es conocido por el 66,7% de los profesionales entrevistados. En cuanto al PS, solo el 66,7% afirma conocerlo, el PSE es conocido por el 86,7% de los entrevistados. Cuando se les preguntó sobre la agenda prioritaria, el 66,7% dijo conocerla. Algunas habilidades de gestión se fomentan mucho, otras no. Entre los estimulados se encuentran: apertura al cambio, ética y profesionalismo y conciencia de calidad, con un 46,7% de los encuestados respondiendo positivamente a estos estímulos. Otras habilidades como actuar de forma preventiva y expresarse críticamente (40% cada una) y conocimiento sobre políticas de salud (53,3%). Además, podemos ver: trabajo en equipo (40%), comunicación (46,7%) y visión estratégica (33,3%). Se fomentan razonablemente otras habilidades: iniciativa y creatividad; y capacidad para liderar personas (26,7% cada una). El 40% de los directivos no se siente animado a participar en los procesos de toma de decisiones. Al final del estudio, se notó la influencia del perfil de los gerentes en la mejora de las prácticas de gestión, ya que mostró las potencialidades y desafíos enfrentados y servirá de base para el proceso de capacitación permanente de los profesionales involucrados en la gestión, traducido en más eficaz y eficiente, proporcionado por el conocimiento y uso de mecanismos de apoyo a la gestión del SUS.
ANALYSIS OF COMPANIES’ CHARACTERISTICS, ECONOMIC CONDITIONS, NET PREMIUMS, AND THEIR IMPACTS ON PROFITABILITY
Authors: Ruchiyat Endang Heddy
Published: December 2020

This research is aimed at empirically testing insurance companies’ profitability and net premiums from the variables of company size, solvability, gross domestic products, and inflation. The research was conducted on general insurance companies in Indonesia observed throughout 2013 – 2017 using the panel data regression. The research results showed: First, company size, solvability, gross domestic products, and inflation have a significant influence on net premiums through the common model effect; secondly, net premiums have a significant influence on profitability through the fixed effect model. This research is expected to be a recommendation and information to the insurance industry, associations, and policymakers.
SURVIVAL PLAN FOR JAPANESE LADIES FASHION AGING SOCIETY OF JAPAN
Authors: Suyama Noriyuki
Published: December 2020

There are many obstacles to establishing successful international business relations, and many fashion industries are still in the process of building reputations outside of the country. Language barriers, differences in governmental policies and regulations, and insufficient market information are all significant obstructions. Thus, currently the main challenges of the Japanese fashion industry are to adapt its products and distribution methods to the changing demographic of an aging domestic population, and to expand and secure its international markets. On the other hands, the aging of Japan is thought to outweigh all other nations, with Japan being purported to have the highest proportion of elderly citizens. In 2014, people aged 65 and older in Japan make up a quarter of its total population, estimated to reach a third by 2050. The dramatic aging of Japanese society as a result of sub-replacement fertility rates and high life expectancy is expected to continue. Both because of challenging environment of overseas market in fashion business and because of unusual current and future demographics in Japan, this paper aims to investigate, focused on the ladies fashion business market in Japan and seek for how to survive and develop in the future.
ACTORS AFFECTING CAREER CHOICE AMONGUNDERGRADUATE STUDENTS IN UNIVERSITY OF ADEN
Authors: Ba Fayadh Wagdi Abdullah , Yusr Maha Mohammed , Mohammed Alqasa Khaled , Alekam Jamal Mohammed Esmail , Mohammed Yusr Yasmin
Published: December 2020

One of the critical aspects of an individual’s life is career choice as this will determine the role pattern needed to be played by the individual in the society in the future,andit is one of the important processes in life. This study aimsto investigate the factors influencing the career choice of the students. This study focusedon undergraduate students in the Universityof Aden. Undergraduate students were chosenbecause right upon graduation, they are the ones who will be decidingon their career choices. The findings of the study largely supported the hypothesizedrelationships proposed in the theoretical model and showed that the family, self-efficacy and economic considerations exerted significant influence on the choice of a career among students. Moreover, the results showed that the influence of family, self-efficacy and economic considerations was positive on career choices. Toinvestigatingstudent’s career choice that isaffected by other important factors, further studies are strongly recommended.
RELATIONSHIP BETWEENBIG FIVE PERSONALITYTRAITS AND ADAPTIVE PERFORMANCE: A CONCEPTUAL PERSPECTIVE IN MALAYSIA HEALTHCARE SECTOR
Authors: Shahidan Athifah Najwani , Abdul Hamid Siti Norasyikin , Ahmad Fais
Published: December 2020

The purpose of this paper is to propose a conceptual framework on the personality traits and adaptive performance of nurses working at the public hospitals in Malaysia. Current paper is intended to examine the relationship between personality traits using Big Five personality elements and its impact to adaptive performance. Moreover, five personality traits have been used as independent variables which are “openness to experience, emotional stability, conscientiousness, agreeableness and extraversion”. Adaptive performance acts as a dependent variable. The findings of the study are supported by the personality theories which is Affective Event Theory (AET). It is assumed to form significant relationship between the personality traits and adaptive performance. For a practical implication, intense focus should be stressed to the factors that can increase employees’ performance especially in public sector to assure the employees is performed well and can deliver the best service to customers. Social implication for this study is the application of adaptive performance will drive to harmonious working environment which can influence to healthy social life, and practice fast respond to reduce the patients’ complaints regarding staff performance in public hospitals.
SYSTEMATIC LITERATURE REVIEW: WORK CONNECTIVITY AFTER HOURS, THE ANTECEDENTS AND EFFECTS TOWARDS INDIVIDUAL EMPLOYEE AND ORGANIZATION
Authors: Abdul Latif Nur Zahidah , Mohd Arif Lily Suriani
Published: December 2020

Mobile technology usage has changed way people work and becoming primary source of communication in the organization. There are few issues and challenges arise in the pursuit of work and personal life balance. Hence, it is important to highlight the antecedents and its effects on individual employee and organization in order to increase the organization efficacy and performance. The research aims to uncover the antecedents and effects of work connectivity after hours towards individual employee and organization as well as examining the underlying theory behind it.The method used by conducting Systematic Literature Review (SLR) in searching the keywords categorized under journals articles and magazines.The results shown in total of 120 related journal articles and magazines were mined based on the criteria that have been set. Only 16 articles were selected for the study after inclusion and exclusion decisions of the articles. Total numbers of five (5) databases were used in the searching process.In conclusion, work connectivity after hours issues have been intensively discussed based on previous existing literature. The highlighted issues can determine the organizational efficacy and effectiveness only if it is well managed and taken into consideration. Nevertheless, there are still rooms for improvement and opened for further discussion yet to obtain the utmost benefits out of it.
STANDARDIZATION OF REQUIREMENTS FOR HIGHER EDUCATION AS A TOOL FOR QUALITY ASSURANCE IN HIGHER EDUCATION: LEVELS OF HIGHER EDUCATION AND SUBJECT AREAS
Authors:   Zaporizhzhia Polytechnic National University, Bakhrushin Vladimir
Published: December 2020

The article discusses some problems of standardization of higher education levels and subject areas in Ukraine, as well as possible ways to solve them. For this purpose, international standardization practices, experience, and problems of creating new higher education standards in Ukraine are considered. According to the Law of Ukraine "On Education", standardization is one of the components of the external quality assurance system in education. Ukrainian legislation provides several levels of standardization – legal requirements, the National Qualifications Framework, higher education standards. The National Qualifications Framework of Ukraine was established in 2011. Today it defines 8 levels corresponding to the levels of the European Qualifications Framework. The new Law of Ukraine "On Higher Education", adopted in 2014, gives higher education institutions significantly greater academic autonomy and provides teachers and students with greater academic freedom. At the same time, it envisages the creation of a new model of quality assurance based on the ESG-2015 and the practices of the EHEA countries. However, the implementation of this model faces a number of problems. Higher education standards should guarantee, on the one hand, the compliance with the level requirements of the NQF, EQF and the QF EHEA, and on the other one, with the needs of the labour market. The formulation of the subject area of ​​the specialty turned out to be one of the serious problems in the development of standards. At the initial stage of work on standards, it was quite common for developers to try to define the subject area through the content of education. Another major challenge was to ensure that the complexity of requirements of the standards meets the NQF levels. Proposals to solve these and some other problems are being discussed.
QUALITY OF UKRAINIAN EDUCATION ACCORDING TO THE RESULTS OF PISA 2018 AND THE OECD PROJECT "FUTURE OF EDUCATION AND SKILLS 2030"
Authors:   SSI «Institute of Educational Analytics», Rakov Sergiy
Published: December 2020

Since its inception in 2000, the international comparative survey of education qua­lity PISA has become a globally recognized powerful lever for improving national education systems, determining their state and development trends according to internationally agreed indicators based on measurements using internationally agreed tools (tests and questionnaires) and procedures for preparation, administration and evaluation of results. In 2015, the OECD launched the "Future of Education and Skills 2030" project, aimed at developing the foundations for an effective education system for the future, the first phase of which culminated in 2019 with the creation of the OECD Learning Compass 2030, a conceptual framework for future school curricula and studying in a learner context. At the second stage, it is planned to create the foundations of effective educating in the context of a teacher. These documents should play the role of the foundation for making the PISA program better by improving, first of all, the PISA subject frameworks in the main domains: reading, mathematics and natural sciences. For the effective improvement of Ukraine's education system, it is important not only to analyse its current state, in particular, its PISA-2018 results, but also to pursue a long-term educational policy aimed at developing an educational model that is based on national educational and cultural achievements and traditions, and is also consistent with the developments of the OECD project "The Future of Education and Skills 2030". The article analyzes the key ideas of the OECD Learning Compass 2030 and discusses some issues of their implementation in the educational practice of Ukraine.
تقييم واقع تطبيق محور المناهج الدراسية وفقا لمعايير الاعتماد الاكاديمي العراقية / دراسة مقارنة لعينة من الجامعات والكليات الحكومية والاهلية
Authors: Wahid Hakim Abdul , Ahmed Youssef Abdel-Allah
Published: December 2020

يهدف البحث للتعرف على تقييم واقع تطبيق محور المناهج من بين معايير الاعتماد الاكاديمي العراقية الثمانية في عينة من الجامعات والكليات الحكومية والاهلية في العراق وتحديد الاسباب الرئيسة والثانوية لها فضلا عن تقديم آليات وإجراءات مقترحة للمساعدة في تقليص الفجوات, اذا تتمثل مشكلة البحث في ضعف توافر متطلبات محور المناهج في الجامعات والكليات (عينة الدراسة) بسبب ضعف التوثيق والتطبيق الناجح لهما وان الاهتمام بهما لا يزال دون مستوى الطموح, وبقصد الوصول الى الحقائق العلمية اعتمد الباحثان المنهج المقارن لإجراء المقارنة ما بين الجامعات الحكومية والكليات الاهلية, وتم بناء قائمة فحص (Check list) التي اعدت وفق مؤشرات محور المناهج, تظهر نتائج البحث بوجود فجوات كبيرة بين واقع الجامعات والكليات وبين متطلبات محور المناهج وتصل الفجوة في احدى الكليات الى (81%), يقدم البحث الاسباب الثانوية والجذرية  للفجوات والتي توفر المعلومات الكافية للجامعات والكليات من اجل التركيز  عليها, وتقدم الاجراءات المقترحة التي تعد من الحلول العملية والعلمية الصحيحة لتقليص الفجوات , وممكن استفادة جميع الكليات والجامعات منها في المساعدة في تطبيق معايير الاعتماد الاكاديمي.
تأثير تطبيق إدارة الجودة الشاملة في القدرة التنافسية من وجهة نظر موظفي الصفوف الأمامية لخدمة الزبائن (دراسة تحليله للمصارف المحلية الفلسطينية)
Authors: Awad Azmi wasfi
Published: December 2020

هدفت الدراسة التعرف على تأثير إدارة الجودة الشاملة في تعزيز القدرة التنافسية من خلال أراء موظفي الصفوف الأمامية لخدمة الزبائن في المصارف المحلية الفلسطينية، واعتمد الباحث على المنهج الوصفي التحليلي من خلال تطوير استبانة خاصة لتحقيق أهداف الدراسة والإجابة عن تساؤلاتها، وشملت الدراسة المصارف المحلية الفلسطينية بفروعها المنتشرة في مناطق الضفة الغربية، وتكون مجتمع الدراسة من 3470 موظف تنفيذي للخدمات المصرفية من اصل 4753 موظف وبنسبة 73%، وبلغت عينة الدراسة (485) موظف اختيروا بالطريقة العشوائية يعملون في الصفوف الامامية لتقديم الخدمات في المصارف المحلية الفلسطينية خلال العام 2019، والقيمة المضافة في هذه الدراسة تمثلت في فحص رأي تلك العينة من المبحوثين، وقد أظهرت نتائج الدراسة عن وجود تأثير ذو دلاله إحصائية لتطبيق إدارة الجودة الشاملة في تعزيز القدرة التنافسية، وبناءً على نتائج الدراسة فقد أوصى الباحث المصارف المحلية الفلسطينية أن تعمق من توظيف إدارة الجودة الشاملة بكافة أبعادها في خدماتها المصرفية لتعزز قدراتها التنافسية، وأن تركز على تنمية وصقل مهارات الموظفين، وتطوير وتنويع الخدمات المصرفية المستندة الى التكنولوجيا الحديثة، وقياس جودة الخدمة المقدمة للزبائن بصورة منتظمة وبأشكال وأساليب مختلفة.
Assessment of Time Spent by Doctors on Medical Documentation- Initial Analysis and Preliminary Study
Authors: Lorkowski Jacek , Grzegorowska Oliwia
Published: December 2020

The aim of the article is evaluation of time needed to spend on filling medical records by Polish surgeons. An anonymous questionnaire concerning time needed to spend on creating particular parts of medical documentation affecting one patient was filled by 80 doctors (40 specialists and 40 residents). 100% of respondents stated that the time spent on medical records is excessive. In the whole study the group time spent on records of one patient was as follows: without patterns and medical secretary 75.62 min (SD 7,4), with patterns – 53.3 min (SD 6.8), with help of medical secretary 36.72 min (SD 5.1). Results in the resident group were as follows: without patterns and medical secretary 110 min (SD 12.4), with patterns – 69.87 min (SD 9.4), with help of medical secretary 46.15 min (SD 6.5). In conclusion, taking legal, formal and logistics measures, could help to reduce the time spent on administrative procedures while generating medical documentation.
Scraps of Hope in Banda Aceh: Gendered Urban Politics in the Aceh Peace Process
Authors: Jauhola Marjaana
Published: December 2020

Scraps of Hope in Banda Aceh offers a critical contribution to the study of post-conflict politics. The book examines the rebuilding of the city of Banda Aceh in Indonesia in the aftermath of the celebrated Helsinki-based peace mediation process, thirty years of armed conflict, and the tsunami. The research is supported by 14 documentary videos reflecting individuals’ experiences on rebuilding the city. In this monograph, Marjaana Jauhola mirrors the peace-making process from the perspective of the ‘outcast’ and invisible, challenging the traditional narrative and ideals of the peace as a success story. Jauhola addresses the alternative futures those stories point towards, and provides alternative ways to reflect the peace dialogue using ethnographic and film documentarist storytelling. Following the lives of people through their everyday experiences in the provincial capital of Banda Aceh, the book offers insights into the relations of power and structures of violence that are embedded in the peace. It tells a story of layered exiles and displacement, revealing hidden narratives of violence and grief while exposing struggles over gendered expectations of being good and respectable women and men. Scraps of Hope in Banda Aceh brings to light the multiple ways of arranging lives and forming caring and loving relationships outside the normative notions of nuclear family and home. The book consists of 7 chapters and 14 documentary videos.
EXPERIMENTAL STUDY ON KCS CONTAINER SHIP INITIAL TURNING AT LOW SPEED IN REGULAR WAVES
Authors: Milanov Evgeni , Efremov Dobrin , Anastasov Anton
Published: December 2020

Since the Energy Efficiency Design Index EEDI was introduced by International Maritime Organization IMO, an increasing attention to the ship's controllability in waves, in particular at low speed is observed. One of the main reasons for this is the fact that, in order to satisfy the EEDI requirements, there is a tendency to reduce the power consumption and the propellers RPM reduction while maintaining existing control means, which results in reduced ship steerability mainly at low speed. This study considers the effect of regular sea waves on ship’s initial turning parameters at the set of service conditions. By means of free running model tests the influence of low advance speed on course and maneuvering trajectory changes in transient turning motion were investigated. The effects of the wave encounter angle variations were examined during the tests, including application of different wave lengths. Using the experimental results, an attempt was made to normalize the ship's handling in adverse sea conditions by applying a simple criterion based on the initial time to reach a given course. The results of the present study can be used for benchmarking of numerical simulations of low speed maneuvers in regular waves.
Novelization of Civil Procedural Legislation of Ukraine in
Cassation Review: Panacea or Illusion?
Authors: Uhrynovska Oksana
Published: December 2020

The article analyzes the novelties introduced to the civil procedural legislation in the cassation review. Cassation proceedings in Ukraine’s current civil proceedings engender a
post-appellate court decision review, the content and purpose of which are to ensure civil
proceeding implementation based on the latter principle application. The author evaluates
cassation filters as a positive step in forming the cassation appeal institution. They
constitute self-limitation of the Supreme Court’s jurisdiction and are designed to relieve it
from reviewing an excessive number of cases. Simultaneously, the current legal regulation
of cassation filters (grounds for appealing court decisions) is far from ideal and needs to
be improved, given the shortcomings highlighted in the study. The non-parties to the case,
possessing the right to cassation appeal, are not always burdened with participation in
the case. Using the example of prosecutor participation in the cassation proceedings, the
author illustrates how national law confers such rights on persons who did not take part
in the case.
A Microeconomic Analysis of the COVID-19 Distribution in Turkey
Authors: AYDOĞAN Yiğit
Published: December 2020

Larger cities do not amplify the COVID-19 pandemic in Turkey. Reports from Turkish cities provide evidence that the Gibrat’s Law holds and the infection grows among population in proportion to the city sizes. Growth of the pandemic is not faster in larger cities. COVID-19 cases are lognormally distributed throughout the country. While the 0-19 age group of the society is associated with a negative impact on the reported cases, 40-59 group has the most additive effect. Distribution of the reported deaths from COVID-19 does not grow in proportion to the city size, and may well be approximated by both exponential and normal distributions.
Almost Para-Contact Metric Structures on 5-dimensional Nilpotent Lie Algebras
Authors: ÖZDEMİR Nilüfer , SOLGUN Mehmet , AKTAY Şirin
Published: December 2020

In this manuscript, almost para-contact metric structures on 5 dimensional nilpotent Lie algebras are studied. Some examples of para-Sasakian and para-contact structures on five-dimensional nilpotent Lie algebras are given.
Research on the influence of entrepreneurial education and entrepreneurial policy on college students' entrepreneurial intention: Intermediary role of entrepreneurial self-efficacy
Authors:   School of Humanities, Economics and Law, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, PR China., Wang Chunping , Sun Shujie ,   School of Humanities, Economics and Law, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, PR China., Zheng Ye ,   School of Humanities, Economics and Law, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, PR China.; School of Public Policy, University of Massachusetts Amherst, Massachusetts 01002, USA.
Published: December 2020

Under the background of the high youth unemployment rate in the world, how to encourage college students to carry out entrepreneurial activities is the focus of the whole society. But even if government and college provide such a high-quality entrepreneurial platform for college students, the rate of youth entrepreneurship in the world is still relatively low. On the basis of the questionnaire of 385 college students concentrated in several colleges in Hubei Province of China, this paper used independent sample T test, single factor analysis method, multiple comparison test (LSD), correlation analysis, regression analysis and other empirical analysis methods to analyze the impact of entrepreneurial education as well as entrepreneurial policy on college students' entrepreneurial intention, and verified the intermediary role of entrepreneurial self-efficacy. The research conclusions mainly included: (1) Part of the control variables will affect entrepreneurial intention; (2) Entrepreneurial education, entrepreneurial policy positively and significantly affect the entrepreneurial intention of college students; (3) Entrepreneurship self-efficacy plays an intermediary role in the influence of entrepreneurship education and entrepreneurial policy on entrepreneurial intention. According to the conclusion of the research, this paper put forward some suggestions for government, university as well as students, and tried to provide the gamut of support system of entrepreneurship, so as to stimulate the entrepreneurial intention of college graduates and improve the entrepreneurial rate.
Why Are Things As They Are? Action Research and the Transformation of Work and Education in the Neoliberal Age
Authors: Ross E. Wayne
Published: December 2020

What we understand about the world is determined by what the world is, who we are, and how we conduct our inquiries.Action research privileges the question “why are things as they are?” This article explores how neoliberalism, with its key principle that competition is the defining characteristic of human relations, reshapes our work as educators and researchers,  and discusses how action research can help us not only better understand our world, but also resist the deleterious effects of neoliberalism on our work and workplaces.
Evaluation of histopathology, PCR, and qPCR to detect Mikrocytos mackini in oysters Crassostrea gigas using Bayesian latent class analysis
Authors: Polinski MP , Laurin E , Delphino MKVC , Lowe GJ , Meyer GR , Abbott CL
Published: December 2020

Latent class analysis (LCA) is a common method to evaluate the diagnostic sensitivity (DSe) and specificity (DSp) for pathogen detection assays in the absence of a perfect reference standard. Here we used LCA to evaluate the diagnostic accuracy of 3 tests for the detection of Mikrocytos mackini in Pacific oysters Crassostrea gigas: conventional polymerase chain reaction (PCR), real-time quantitative PCR (qPCR), and histopathology. A total of 802 Pacific oysters collected over 12 sampling events from 9 locations were assessed. Preliminary investigations indicated that standard LCA assumptions of test independence and constant detection accuracy across locations were likely unrealistic. This was mitigated by restructuring the LCA in a Bayesian framework to include test-derived knowledge about pathogen prevalence and load for categorizing populations into 2 classes of infection severity (low or high) and assessing separate DSe and DSp estimates for each class. Median DSp estimates were high (>96%) for all 3 tests in both population classes. DSe estimates varied between tests and population classes but were consistently highest for qPCR (87-99%) and lowest for histopathology (21-51%). Acknowledging that detection of M. mackini may be fitted to multiple diagnostic and management purposes, qPCR had the highest DSe while maintaining similar DSp to both conventional PCR and histopathology and thus is generally well-suited to most applications.
Rancang Bangun Marketplace Pemesanan Jasa Dokumentasi Foto dan Video Pernikahan Berbasis Web
Authors: Pratama Yudha I Putu Wira Cahaya , Suarjaya I Made Agus Dwi , Raharja I Made Sunia
Published: December 2020

Momen pernikahan menjadi momen yang langka bagi pasangan pengantin dan keluarganya sehingga dokumentasi foto maupun video cukup penting untuk mengabadikan momen. Selain itu fenomena prewedding yaitu prosesi dokumentasi kemesraan calon pengantin dalam masa persiapan pernikahan (pra-pernikahan) sudah ditemui dan populer sejak tahun 2000-an. Pelaku usaha penyedia jasa dokumentasi pernikahan maupun prewedding khususnya di Bali sudah semakin menjamur. Masalah yang terjadi dari pihak pengguna jasa yaitu minimnya informasi ketika mencari jasa yang sesuai sehingga pengguna jasa memerlukan waktu dan tenaga yang kurang efektif. Sedangkan pihak penyedia jasa memiliki masalah dari sisi pemasaran yang kurang bisa mencangkup pasar yang luas dan penyaluran informasi spesifikasi jasa yang diberikan yang kurang baik. Solusi yang dapat dilakukan pada era digital dan serba menggunakan internet ini adalah pengimplementasian sistem marketplace pemesanan jasa dokumentasi pernikahan berbasis web. Sistem ini menjadi wadah atau media bertemunya para pengguna jasa dan penyedia jasa dengan mudah. Berdasarkan hasil kuisioner terhadap 20 orang menghasilkan persentase rata-rata pengujian pada aspek antar muka sistem yang menjawab sangat setuju sebanyak 34%, setuju sebanyak 57%, dan netral sebanyak 9% serta pada aspek kinerja proses dan fitur sistem menghasilkan persentase rata-rata jawaban sangat setuju sebanyak 43%, setuju sebanyak 48%, dan netral sebanyak 9%.
Electrospinning With Lyophilized Platelet-Rich Fibrin Has the Potential to Enhance the Proliferation and Osteogenesis of MC3T3-E1 Cells
Authors: Nie Jing , Zhang Shumei , Wu Peng , Liu Yuangang , Su Yanjun
Published: December 2020

Platelet-rich fibrin (PRF) as a reservoir of various growth factors plays an essential role in wound healing and tissue engineering at present. Electrospinning technology is an efficient approach to acquire artificial scaffold which has large specific surface area and high porosity. The goal of this study was to investigate the potential of electrospinning on the proliferation and osteogenesis of osteogenic precursor cells in vitro, with lyophilized PRF added as a component for electrospinning preparation. The surface structure of lyophilized PRF and nanofibers were investigated, and the proliferation, osteogenesis of MEC3T3-E1 cells with lyophilized PRF or nanofibers extract were studied. The results showed that the diameters of the lyophilized PRF pores were 1.51 ± 0.75 μm, and lyophilized PRF medium promoted the proliferation and osteocalcin (OCN) and osteopontin (OPN) genes expression of MEC3T3-E1 cells. Furthermore, the diameters of the polyvinyl alcohol/sodium alginate/lyophilized PRF (PVA/SA/PRF) fibers were 201.14 ± 40.14 nm. Compared to PVA/SA nanofibers extract and control medium, PVA/SA/PRF nanofibers extract also enhanced the proliferation and mineralization activity of MEC3T3-E1 cells. These results might be instructive to future therapeutics with PVA/SA/PRF electrospinning for bone tissue engineering or other applications.
The Effects of DPP-4 Inhibitors, GLP-1RAs, and SGLT-2/1 Inhibitors on Heart Failure Outcomes in Diabetic Patients With and Without Heart Failure History: Insights From CVOTs and Drug Mechanism
Authors: Pan Xiaohui , Xu Shishi , Li Juan , Tong Nanwei
Published: December 2020

Patients with type 2 diabetes (T2D) have a higher risk of heart failure (HF) than healthy people, and the prognosis of patients with diabetes and current or previous HF is worse than that of patients with only diabetes. We reviewed the HF outcomes in recently published cardiovascular outcome trials (CVOTs) of three new classes of anti-diabetic agents, namely, dipeptidyl peptidase-4 inhibitors (DPP-4is), glucagon-like-peptide 1 receptor agonists (GLP-1RAs), and sodium glucose cotransporter-2 inhibitors (SGLT-2is) or SGLT-2 and SGLT-1 dual inhibitors and divided the patients into two groups based on the history of HF (with or without) and analyzed their risks of HHF based on the receipt of the aforementioned anti-diabetes drug types. Since the follow-up period differed among the trials, we expressed the rate of HHF as events/1,000 person-years to describe the HF outcome. At last we pooled the data and analyzed their different effects and mechanisms on heart failure outcomes. Although DPP-4is did not increase the risk of HHF in T2D patients with a history of HF, they were associated with a significantly higher risk of HHF among patients without history of HF. Some GLP-1RAs reduced the risk of macrovascular events, but none of these drugs reduced the risk of HHF in patients with T2D irrespective of their HF history. It was not clarified whether SGLT-1/2is can improve the prognosis of macrovascular events in patients with T2D, but these drugs reduced the risk of HHF regardless of patients’ histories of HF. This information may be useful or referential for the “precise” selection of hyperglycemic medications. Further researches still needed to clarify the mechanisms of these anti-diabetic medications.
Eosinophils in Eosinophilic Esophagitis: The Road to Fibrostenosis is Paved With Good Intentions
Authors: Doyle Alfred D. , Masuda Mia Y. , Kita Hirohito , Wright Benjamin L.
Published: December 2020

Eosinophilic esophagitis (EoE) is an antigen-driven disease associated with epithelial barrier dysfunction and chronic type 2 inflammation. Eosinophils are the defining feature of EoE histopathology but relatively little is known about their role in disease onset and progression. Classically defined as destructive, end-stage effector cells, eosinophils (a resident leukocyte in most of the GI tract) are increasingly understood to play roles in local immunity, tissue homeostasis, remodeling, and repair. Indeed, asymptomatic esophageal eosinophilia is observed in IgE-mediated food allergy. Interestingly, EoE is a potential complication of oral immunotherapy (OIT) for food allergy. However, we recently found that patients with peanut allergy may have asymptomatic esophageal eosinophilia at baseline and that peanut OIT induces transient esophageal eosinophilia in most subjects. This is seemingly at odds with multiple studies which have shown that EoE disease severity correlates with tissue eosinophilia. Herein, we review the potential role of eosinophils in EoE at different stages of disease pathogenesis. Based on current literature we suggest the following: (1) eosinophils are recruited to the esophagus as a homeostatic response to epithelial barrier disruption; (2) eosinophils mediate barrier-protective activities including local antibody production, mucus production and epithelial turnover; and (3) when type 2 inflammation persists, eosinophils promote fibrosis.
Antioxidant and Antiproliferative Activity of Allium ursinum and Their Associated Microbiota During Simulated in vitro Digestion in the Presence of Food Matrix
Authors: Stanisavljević Nemanja , Soković Bajić Svetlana , Jovanović Živko , Matić Ivana , Tolinački Maja , Popović Dušanka , Popović Nikola , Terzić-Vidojević Amarela , Golić Nataša , Beškoski Vladimir , Samardžić Jelena
Published: December 2020

In this study, for the first time, the comprehensive analysis of antiproliferative and antioxidant activities of ramson, followed by the analysis of its associated microbiota and health-promoting effects of lactic acid bacteria (LAB), was performed. Ramson (Allium ursinum) is recognized as a medicinal plant with a long history of use in traditional medicine due to its antimicrobial and antioxidant activity. In this study the influence of in vitro gastrointestinal digestion on the cytotoxic activity of A. ursinum extracts against human malignant cell lines was demonstrated. Seven sulfur compounds, the degradation products of thiosulfinates, including diallyl disulfide were shown to inhibit proliferation of malignant cells by inducing accumulation within G2/M phase as well as to induce apoptosis through activation of caspase-3 and mitochondrial signaling pathway. Further, the A. ursinum microbiota, particularly LAB with potential probiotic effects, was analyzed by culture-dependent method and culture-independent method [denaturing gradient gel electrophoresis (DGGE)]. The obtained results revealed that the most abundant genera were Streptococcus, Lactobacillus, and Bacillus. The Lactobacillus genus was mainly represented by L. fermentum. The pulsed-field gel electrophoresis (PFGE) analysis revealed the presence of two PFGE pulsotypes. The probiotic potential of the strain L. fermentum BGSR163 belonging to PFGE pulsotype 1 and the strain L. fermentum BGSR227 belonging to the PFGE pulsotype 2 was characterized. The results revealed that both strains are safe for human use, successfully survive the simulated gastrointestinal conditions, have potential to transiently colonize the gastrointestinal tract (GIT) and have a protective immunomodulatory effect, inducing the production of proinflammatory cytokine IL17 and regulatory cytokine IL10, while decreasing the production of proinflammatory cytokine IFN-γ. In conclusion, the results of this study suggest that consumption of A. ursinum might have health-promoting properties, including anticancer effects, while L. fermentum strains isolated from A. ursinum leaves could be used as probiotics for human consumption.
Vesicular Release of GABA by Mammalian Horizontal Cells Mediates Inhibitory Output to Photoreceptors
Authors: Hirano Arlene A. , Vuong Helen E. , Kornmann Helen L. , Schietroma Cataldo , Stella Salvatore L. , Barnes Steven , Brecha Nicholas C.
Published: December 2020

Feedback inhibition by horizontal cells regulates rod and cone photoreceptor calcium channels that control their release of the neurotransmitter glutamate. This inhibition contributes to synaptic gain control and the formation of the center-surround antagonistic receptive fields passed on to all downstream neurons, which is important for contrast sensitivity and color opponency in vision. In contrast to the plasmalemmal GABA transporter found in non-mammalian horizontal cells, there is evidence that the mechanism by which mammalian horizontal cells inhibit photoreceptors involves thevesicular releaseof the inhibitory neurotransmitter GABA. Historically, inconsistent findings of GABA and its biosynthetic enzyme, L-glutamate decarboxylase (GAD) in horizontal cells, and the apparent lack of surround response block by GABAergic agents diminished support for GABA's role in feedback inhibition. However, the immunolocalization of the vesicular GABA transporter (VGAT) in the dendritic and axonal endings of horizontal cells that innervate photoreceptor terminals suggested GABA was released via vesicular exocytosis. To test the idea that GABA is released from vesicles, we localized GABA and GAD, multiple SNARE complex proteins, synaptic vesicle proteins, and Cavchannels that mediate exocytosis to horizontal cell dendritic tips and axonal terminals. To address the perceived relative paucity of synaptic vesicles in horizontal cell endings, we used conical electron tomography on mouse and guinea pig retinas that revealed small, clear-core vesicles, along with a few clathrin-coated vesicles and endosomes in horizontal cell processes within photoreceptor terminals. Some small-diameter vesicles were adjacent to the plasma membrane and plasma membrane specializations. To assess vesicular release, a functional assay involving incubation of retinal slices in luminal VGAT-C antibodies demonstrated vesicles fused with the membrane in a depolarization- and calcium-dependent manner, and these labeled vesicles can fuse multiple times. Finally, targeted elimination of VGAT in horizontal cells resulted in a loss of tonic, autaptic GABA currents, and of inhibitory feedback modulation of the cone photoreceptor Cai, consistent with the elimination of GABA release from horizontal cell endings. These results in mammalian retina identify the central role of vesicular release of GABA from horizontal cells in the feedback inhibition of photoreceptors.
Neuronal–Glial Interaction in a Triple-Transgenic Mouse Model of Alzheimer’s Disease: Gene Ontology and Lithium Pathways
Authors: Rocha Nicole Kemberly R. , Themoteo Rafael , Brentani Helena , Forlenza Orestes V. , De Paula Vanessa De Jesus Rodrigues
Published: December 2020

Neuronal-glial interactions are critical for brain homeostasis, and disruption of this process may lead to excessive glial activation and inadequate pro-inflammatory responses. Abnormalities in neuronal-glial interactions have been reported in the pathophysiology of Alzheimer’s disease (AD), where lithium has been shown to exert neuroprotective effects, including the up-regulation of cytoprotective proteins. In the present study, we characterize by Gene Ontology (GO) the signaling pathways related to neuronal-glial interactions in response to lithium in a triple-transgenic mouse model of AD (3×-TgAD). Mice were treated for 8 months with lithium carbonate (Li) supplemented to chow, using two dose ranges to yield subtherapeutic working concentrations (Li1, 1.0 g/kg; and Li2, 2.0 g/kg of chow), or with standard chow (Li0). The hippocampi were removed and analyzed by proteomics. A neuronal-glial interaction network was created by a systematic literature search, and the selected genes were submitted to STRING, a functional network to analyze protein interactions. Proteomics data and neuronal-glial interactomes were compared by GO using ClueGo (Cytoscape plugin) with p ≤ 0.05. The proportional effects of neuron-glia interactions were determined on three GO domains: (i) biological process; (ii) cellular component; and (iii) molecular function. The gene ontology of this enriched network of genes was further stratified according to lithium treatments, with statistically significant effects observed in the Li2 group (as compared to controls) for the GO domains biological process and cellular component. In the former, there was an even distribution of the interactions occurring at the following functions: “positive regulation of protein localization to membrane,” “regulation of protein localization to cell periphery,” “oligodendrocyte differentiation,” and “regulation of protein localization to plasma membrane.” In cellular component, interactions were also balanced for “myelin sheath” and “rough endoplasmic reticulum.” We conclude that neuronal-glial interactions are implicated in the neuroprotective response mediated by lithium in the hippocampus of AD-transgenic mice. The effect of lithium on homeostatic pathways mediated by the interaction between neurons and glial cells are implicated in membrane permeability, protein synthesis and DNA repair, which may be relevant for the survival of nerve cells amidst AD pathology.
A Brief Assessment of Body Image Perception: Norm Values and Factorial Structure of the Short Version of the FKB-20
Authors: Schmalbach Ileana , Schmalbach Bjarne , Zenger Markus , Berth Hendrik , Albani Cornelia , Petrowski Katja , Brähler Elmar
Published: December 2020

The Body Image Questionnaire-20 (FKB-20) is one of the most applied self-report measures in the context of body image assessment in German-speaking regions. A version of the FKB-20 capturing an ideal concept of body image is also available. A special property of the scale is its high sensitivity for individuals suffering from anorexia nervosa. The present research provided a short version of this scale (for both variants) and examined its validity in a representative sample (N= 2,347) of the German population. We utilized factor analysis methods to identify the optimal short scale of the measure, finding excellent model fit and reliability for a two-factor model (FKB-6) for both real and ideal body image. Both versions of the FKB-6 can be considered invariant across sex and age groups. Good reliability indices were shown for both versions of the FKB-6. The reliability indices were similar to those mentioned in previous studies. Our study also revealed, that large discrepancies between the real and an ideal body image are correlated with somatic and body dysmorphic symptoms. Finally, we provided norm values for comparisons of individual scores with the general population. The FKB-6 is a valid and a reliable measure that economizes assessments by clinicians and researchers.
Trait Procrastination and Mobile Phone Addiction Among Chinese College Students: A Moderated Mediation Model of Stress and Gender
Authors: Yang Xiaofan , Wang Pengcheng , Hu Ping
Published: December 2020

Recent studies have indicated that trait procrastination as a personality factor could lead to mobile phone addiction, however little is known about the mediating and moderating mechanisms underlying this process. The current study investigated the mediating role of stress in the relationship between trait procrastination and mobile phone addiction, and whether the mediating effect was moderated by gender. A sample including 1,004 Chinese college students completed measurements of trait procrastination, stress, mobile phone addiction, and demographic information. The results showed that trait procrastination was positively related to college students’ mobile phone addiction. Mediation analyses revealed that this relationship was partially mediated by stress. Moderated mediation further indicated that the path between trait procrastination and stress was stronger for male students compared with female students. These findings broadened our knowledge of the underlying mechanisms between trait procrastination and mobile phone addiction, the implications and limitations of this study were discussed.