bluuebunny/crossref_metadata_2025 huggingface dataset:
Fibroblast growth factor 10 alleviates acute lung injury by inhibiting excessive autophagy via Nrf2
Authors: Huang Shuai , Xue Yincong , Chen Wanying , Xue Mei , Miao Lei , Dong Li , Zuo Hao , Wen Hezhi , Lei Xiong , Xu Zhixiao , Quan Meiyu , Guo Lisha , Zheng Yawen , Wang Zhendong , Yang Li , Li Yuping , Chen Chengshui
Published: July 2023

Acute lung injury (ALI) is associated with an increased incidence of respiratory diseases, which are devastating clinical disorders with high global mortality and morbidity. Evidence confirms that fibroblast growth factors (FGFs) play key roles in mediating ALI. Mice were treated with LPS (lipopolysaccharide: 5 mg/kg, intratracheally) to establish an in vivo ALI model. Human lung epithelial BEAS-2B cells cultured in a corresponding medium with LPS were used to mimic the ALI model in vitro. In this study, we characterized FGF10 pretreatment (5 mg/kg, intratracheally) which improved LPS-induced ALI, including histopathological changes, and reduced pulmonary edema. At the cellular level, FGF10 pretreatment (10 ng/mL) alleviated LPS-induced ALI accompanied by reduced reactive oxygen species (ROS) accumulation and inflammatory responses, such as IL-1β, IL-6, and IL-10, as well as suppressed excessive autophagy. Additionally, immunoblotting and co-immunoprecipitation showed that FGF10 activated nuclear factor erythroid-2-related factor 2 (Nrf2) signaling pathway via Nrf2 nuclear translocation by promoting the interaction between p62 and keap1, thereby preventing LPS-induced ALI. Nrf2 knockout significantly reversed these protective effects of FGF10. Together, FGF10 protects against LPS-induced ALI by restraining autophagy via p62-Kelch-like ECH-associated protein 1 (Keap1)-Nrf2 signaling pathway, implying that FGF10 could be a novel therapy for ALI.
BRD7 improves glucose homeostasis independent of IRS proteins
Authors: Kim Yoo , Lee Junsik M , Han Youngah , Tao Rongya , White Morris F , Liu Renyan , Park Sang Won
Published: July 2023

Bromodomain-containing protein 7 (BRD7) has emerged as a player in the regulation of glucose homeostasis. Hepatic BRD7 levels are decreased in obese mice, and the reinstatement of hepatic BRD7 in obese mice has been shown to establish euglycemia and improve glucose homeostasis. Of note, the upregulation of hepatic BRD7 levels activates the AKT cascade in response to insulin without enhancing the sensitivity of the insulin receptor (InsR)–insulin receptor substrate (IRS) axis. In this report, we provide evidence for the existence of an alternative insulin signaling pathway that operates independently of IRS proteins and demonstrate the involvement of BRD7 in this pathway. To investigate the involvement of BRD7 as a downstream component of InsR, we utilized liver-specific InsR knockout mice. Additionally, we employed liver-specific IRS1/2 knockout mice to examine the requirement of IRS1/2 for the action of BRD7. Our investigation of glucose metabolism parameters and insulin signaling unveiled the significance of InsR activation in mediating BRD7’s effect on glucose homeostasis in the liver. Moreover, we identified an interaction between BRD7 and InsR. Notably, our findings indicate that IRS1/2 is not necessary for BRD7's regulation of glucose metabolism, particularly in the context of obesity. The upregulation of hepatic BRD7 significantly reduces blood glucose levels and restores glucose homeostasis in high-fat diet-challenged liver-specific IRS1/2 knockout mice. These findings highlight the presence of an alternative insulin signaling pathway that operates independently of IRS1/2 and offer novel insights into the mechanisms of a previously unknown insulin signaling in obesity.
As the Epitome of Talent: John von Neumann and Hungarian-born Scientists Around Him
Authors: KÉPES Gábor , ERDŐSNÉ NÉMETH Ágnes
Published: July 2023

John von Neumann (1903–1957) was a Hungarian-American mathematician, physicist,
computer scientist, and polymath who made significant contributions to various fields of science and technology. He is best-known for his pioneering work in computer science, game theory, and the development of the Neumann architecture, which forms the basis of most modern computers.
Neumann’s work laid the foundation for the development of the digital computer, and he is often regarded as one of the founding figures of the field of computer science. He made important contributions to the development of early computing machines, including the concept of storedprogram computers, which enabled computers to store and manipulate instructions as data, and the idea of self-replicating machines, which has been influential in the field of artificial intelligence and robotics.
In addition to his work in computer science, Neumann made significant contributions to other fields, such as mathematics, physics, economics, and nuclear physics. He also played a key role in the development of the atomic bomb during World War II as part of the Manhattan Project.
Neumann’s work has had a profound impact on modern science, technology, and society, and his legacy continues to inspire and influence researchers and practitioners in various fields. His visionary ideas and interdisciplinary approach to problem-solving make him a remarkable figure in the history of science and technology.
CONTRIBUTION TO KNOWLEDGE ON THE TAXONOMIC COMPOSITION AND DISTRIBUTION OF NOCTUOID MOTHS (LEPIDOPTERA: NOCTUOIDEA) OF UKRAINE
Authors: Geryak Yu. M. , Khalaim Ye. V. , Suchkov S. I. , Zhakov O. V. , Bachynskyi A. I. , Bezuglyi S. K. , Bidychak R. M. , Galkin O. O. , Gera A. A. , Kavurka V. V. , Kovalchuk D. O. , Kozlov S. M. , Leshchenko M. V. , Novytskyi S. M. , Parkhomenko V. V. , Prostebi V. L. , Sergienko V. M. , Trotsenko S. M. , Tsykal S. V. , Voitko P. L. , Voronov V. K. , Yepishin V. V. , Zaika M. I.
Published: July 2023

The paper contains data on the distribution of 265 species of Noctuoid moths (Lepidoptera: Noctuoidea), that are little-known, new for different regions or local and rare in Ukraine. One species, Episema amasina, is reliably registered for the first time in Ukraine and Europe as a whole; four species, Eublemma porphyrina, Grammodes bifasciata, Oncocnemis nigricula and Conistra ragusae, are recorded for the first time in Ukraine; three species: Dysauxes famula, Aporophyla nigra and Divaena haywardi are first revealed on the mainland of Ukraine; and one species, Mythimna congrua is found for the first time in the Ukrainian Carpathians and western part of Ukraine as a whole. A number of species appeared to be recorded for the first time in certain regions of Ukraine: 27 species — in Poltava Region, 25 — in Odesa Region, 19 — in Kirovohrad Region, 17 — in Kherson Region, 12 — in Ivano-Frankivsk Region, 9 — in Vinnytsia Region, 8 — in Zaporizhzhia Region, 7 — in Kyiv Region, 6 each — in Donetsk and Khmelnytskyi Regions, 5 each — in Chernihiv, Luhansk and Mykolaiv Regions, 4 each — in Volyn and Zhytomyr Regions, 3 — in Rivne Region, 2 each — in Chernivtsi, Sumy and Ternopil Regions, and one each — in Cherkasy, Kharkiv and Zakarpattia Regions. Moreover, new records for a number of local, rare and little-known (yet insufficiently studied in Ukraine) species, are also given.
Quando uma palavra toca a outra
Authors: Lopes Jader Janer Moreira , Paula Sara Rodrigues Vieira de
Published: July 2023

Neste texto, desejamos dialogar sobre a espacialização da vida de bebês e crianças nas cidades, a partir de um olhar sobre a urbanização e sobre o viver em diferenciados territórios. Nossa reflexão se faz a partir da condição do beco, como uma expressão espacial desacostumada, que tem a força e a potência das próprias infâncias. Contaremos, assim, as histórias dos becos, em formas de geografias, com as crianças e com os bebês, para, com eles, olharmos suas vivências espaciais e o seu direito à cidade. Este artigo é um encontro com outros, um ajuntar de vozes oriundas não só de outras pesquisas, mas com autores acadêmicos e, também, com a literatura. Trata-se de um ensaio que busca colocar em interface os temas centrais presentes no próprio título. Nessa perspectiva, busca-se pensar o direito à criação de outra forma de espacialidade, em que está posta a própria condição de humanização e, em especial, a dimensão da topogênese como uma das marcas a ser apreciada. Defendemos que a garantia do direito a (outra) cidade deve ter como princípio não somente a tão apontada autonomia espacial, mas, junto a ela, a garantia da autoria espacial e do desenvolvimento em sua totalidade.
Wind Turbine Towers: Precast Concrete Hexcrete May Help Increase Renewable Energy Capacity with Taller Hub Heights
Authors: Sritharan Sri
Published: July 2023

Wind-energy production has been growing rapidly in the Midwest, but not in other regions of the United States. Increased wind-turbine hub heights of 328 to 459 ft (100 to 140 m) could drastically change this. As wind-turbine towers get taller than 263 ft (80 m), a concrete solution may become more cost-effective than the steel tubular option. The Hexcrete concept was developed with the aim of revolutionizing wind-turbine towers for hub heights of 328 ft (100 m) and more. This tower uses hexagonal columns with posttensioning and rectangular/tapered panels as bracing elements. The prefabricated modules are assembled using posttensioning to form a tapered tower with a hexagonal cross section. Large-scale testing has been used to validate the Hexcrete concept and its connections.
Changes in the haemocoagulation system after pregravid preparation before ART programme in pregnant women with a history of sexually transmitted infections
Authors:   Shupyk National Healthcare University of Ukraine, Kyiv, Krotik О.I.
Published: July 2023

Purpose - to analyze the dynamics of laboratory parameters of haemocoagulation system functioning after pregravid preparation before assisted reproductive technologies (ART) cycles in pregnant women with a history of sexually transmitted infections (STIs). Materials and methods. The functioning of the haemocoagulation system after the ART program in women with infertility and a history of STIs was analyzed: the Group 1 - 56 pregnant women received the treatment and preventive measures proposed by us in the pregravid period; the Group 2 - 55 pregnant women received conventional treatment and preventive measures. The state of the hemostasis system was assessed by the following indicators: fibrinogen concentration, activated recalcification time, activated partial thromboplastin time (APTT), integrative «index of thrombodynamic potential» (ITP), concentration of fibrin and fibrinogen degradation products (FDP) and the level of more stable but less biologically active metabolites of prostacyclin (6-keto-PGF1α) and thromboxane (T×B2). The statistical processing of the study results was performed using standard software «Microsoft Excel 5.0» and «Statistica 8.0». Results. During the period of final formation of the placental barrier in pregnant women of the Group 1, the APTT slowly lengthened (31.3±1.6 s - in the trimester ІІ; 34.3±2.9 s - in the trimester III) with increasing gestational age and significantly differed from the indicators in the Group 2 (27.6±3.0 s and 30.2±1.7 s, respectively; p<0.05); activated recalcification time slowly decreased during the trimesters II and III of gestation in pregnant women of the Group 1 (63.1±2.8 s and 59.3±2.8 s, respectively); gradually decreased the level of FDP (5.8±0.27×10-2 g/l and 5.1±0.22×10-2 g/l), in contrast to the level of FDP in the Group 2, in which this indicator gradually increased (9.4±0.17×10-2 g/l and 11.6±0.27×10-2 g/l); (p<0.01). The level of stable T×B2 in the trimester II decreased by 2 times and was lower (p<0.05) than in the Group 2; the level of stable 6-keto-PGF1α increased in the trimester III (p<0.05). This resulted in an increase in the PgI2/T×A2 balance in the Group 1 from 0.34±0.02 to 1.16±0.03, which corresponded to the physiological needs of systemic and organ hemodynamics during pregnancy. Conclusions. The development and implementation of effective pregravid preparation before ART cycles in women with a history of STIs and medical correction during pregnancy contribute to the increase of the adaptive compensatory and adaptive potential of maternal haemocoagulation homeostasis and perinatal fetal care. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.
a (im)possibilidade da formação de coisa julgada material na tutela de urgência antecipada concedida em caráter antecedente, após o decurso do prazo bienal do artigo 304, §5° do cpc.
Authors: Bolesina Iuri , Zanchett Natália
Published: July 2023

O artigo analisa o seguinte problema: com o decurso do prazo bienal do artigo 304, §5° do CPC, sem ação revocatória, a tutela antecipada antecedente estabilizada forma coisa julgada material? A metodologia aplicada é hipotética dedutiva, o método de procedimento monográfico e a técnica de pesquisa a documentação indireta. Concluiu-se não haver formação de coisa julgada material na tutela antecipada antecedente, por: (i) inexistir decisão advinda de cognição exauriente, (ii) serem próprios os objetivos da estabilização, (iii) a opção legislativa e (Iv) por ser a estabilização impeditiva à propositura de ação que não a revocatória durante o período bienal.
A implementação de práticas autocompositivas no Brasil: alcances e limites na concretização da terceira onda de acesso à justiça do Projeto Florença
Authors: Stangherlin Camila Silveira
Published: July 2023

O presente artigo tem por objetivo analisar a implementação das ideias oriundas do estudo que culminou nas ondas de acesso à justiça do Projeto Florença no contexto brasileiro, especialmente, ao que se refere à terceira onda e sua correlação com as políticas públicas de autocomposição de conflitos. O problema de pesquisa visa responder: quais os alcances derivados da instituição da terceira onda de acesso à justiça por intermédio das políticas públicas autocompositivas no Brasil, e, quais os limites encontrados para sua efetivação? Nesse aspecto, o método de abordagem é o dedutivo e o levantamento de dados se dá por fontes primárias e fontes secundárias (pesquisa documental e pesquisa bibliográfica). As conclusões principais apontam para o fortalecimento de ações que respaldam o acesso à justiça pelo viés democrático, consubstanciando as ideias da primeira e segunda onda do Projeto Florença. Por sua vez, as conquistas advindas da terceira onda de acesso à justiça são mais tardias no país, encontrando óbices de natureza formal e burocrática, e, de centralização jurisdicional.
Information-Theoretic Representation of Interception Network Channel Virtualization
Authors: Sinyuk Alexander , Ostroumov Oleg , Tarasov Alexander
Published: July 2023

The most difficult task of secure telecommunication systems using symmetric encryption, due to the need for preliminary and resource-intensive organization of secret channels for delivering keys to network correspondents, is key management. An alternative is the generating keys methods through open communication channels. In information theory, it is shown that these methods are implemented under the condition that the channel information rate of correspondents exceeds the rate of the intruder interception channel. The search for methods that provide the informational advantage of correspondents is being updated. The goal is to determine the information-theoretical conditions for the formation of a virtual network and an interception channel, for which the best ratio of information speeds for correspondents is provided compared to the ratio of the original network and interception channel. The paper proposes an information transfer model that includes a connectivity model and an information transfer method for asymptotic lengths of code words. The model includes three correspondents and is characterized by the introduction of an ideal broadcast channel in addition to an errored broadcast channel. The model introduces a source of "noisy" information, which is transmitted over the channel with errors, so the transmission of code words using the known method of random coding is carried out over the channel without errors. For asymptotic lengths of code words, all actions of correspondents in processing and transmitting information in the model are reduced to the proposed method of transmitting information. The use of the method by correspondents within the framework of the transmission model makes it possible to simultaneously form for them a new virtual broadcast channel with information rate as in the original channel with errors, and for the intruder a new virtual broadcast interception channel with a rate lower than the information rate of the initial interception channel. The information-theoretic conditions for deterioration of the interception channel are proved in the statement. The practical significance of the results obtained lies in the possibility of using the latter to assess the information efficiency of open network key formation in the proposed information transfer model, as well as in the development of well-known scientific achievements of open key agreement. The proposed transmission model can be useful for researching key management systems and protecting information transmitted over open channels. Further research is related to the information-theoretic assessment of the network key throughput, which is the potential information-theoretic speed of network key formation.
Optimal Nonlinear Filtering of Information Impact Estimates in a Stochastic Model of Information Warfare
Authors: Polansky Ivan , Loginov Kirill
Published: July 2023

A computationally efficient algorithmic solution to the problem of optimal nonlinear filtering of information impact estimates in a generalized stochastic model of information warfare is developed in the article. The formed solution is applicable in the presence of heterogeneous rules for measuring the parameters of the information warfare model, on the basis of which a pair of systems of stochastic differential equations is formed. According to the criterion of maximum likelihood according to the determined evolution of the a posteriori conditional probability density function at a given observation interval, the evaluation of the information impact in the optimal nonlinear filtering model is performed. Taking into account the probability addition theorem, as the probability of the sum of two joint events, the density functions of which are established from the numerical solution of the corresponding robust Duncan-Mortensen-Zakai equations, finding a posteriori conditional probability density function at a given time is performed. For the first event, it is assumed that the first system of stochastic differential equations is the equation of state, and the second – is the equation of observation. For the second event, their definition is set in reverse order. The solution of the robust Duncan-Mortensen-Zakai equation is carried out in the formulation of the Galerkin spectral method when sampling the observation interval into subintervals and reducing the initial solution to a numerical recurrent study of the sequence of subtasks using the so-called Yau-Yau's algorithm, which assumes an estimate of the probability measure from the solution of the direct Kolmogorov equation with its subsequent correction by observation. To highlight the features of the algorithmic implementation of the compiled solution, an algorithm for optimal nonlinear filtering of information impact estimates in a generalized stochastic model of information confrontation when specifying the listing of the function implementing it, which is represented by a pseudocode, has been formed. To identify the preference of the compiled algorithmic solution for optimal nonlinear filtering of information impact assessments, a series of computational experiments on large-volume test samples was carried out. The result of the information impact assessment obtained by the proposed algorithm is compared with the determined solution: 1) by the average sample values from the observation models; 2) by an ensemble extended Kalman filter; 3) by a filtering algorithm involving a numerical study of the Duncan-Mortensen-Zakai equation. According to the conducted a posteriori study, quantitative indicators that establish the gain of the compiled algorithm and the limits of its applicability are highlighted.
Errors Compensation Caused by Time Delay of Digital Sensors
Authors: Gaiduk Anatoly , Prokopenko Nikolay , Bugakova Anna
Published: July 2023

The paper is devoted to improving the accuracy of digital sensors with a time lag. The relevance of the topic is due to the widespread use of sensors of this type, which is largely due to a sharp increase in the requirements for measurement accuracy. The timeliness is associated also with the extensive application of digital technologies for information processing in control systems, communications, monitoring and many others. To eliminate the errors caused by the time delay of digital sensors, it is suggested to use an astatic high-speed corrector. The applicability of this corrector is justified by the properties of discrete-time dynamical systems. In this regard, at first, the conditions are considered under which the discrete systems are physically realizable and have a finite duration of the transient since in this latter case they are the fastest. It is also shown that in order to measure a polynomial signal of limited intensity with zero error in steady-state mode, the astatism order of the sensor must be one value greater than the degree of this signal. Based on the above conditions, the main result of the article is proved – a theorem in which the conditions for the existence of the astatic high-speed corrector are established. When this corrector is switched on at the output of the digital sensor or when its software is being corrected an upgraded sensor is formed, the error of which will be zero in steady-state mode. This is due to the fact that the corrector eliminates the error of the digital sensor caused by its time delay, which is assumed to be multiple of the sampling period. The order of the corrector as a system is determined by the integer solution of the equation obtained in the work, which relates the degree of the measured polynomial signal, the time delay of the digital sensor, the permissible overshoot of the upgraded sensor and the relative order of the desired corrector. This equation is solved for the cases, where the degree of the measured signals is not greater than one, the overshoot is equal to the frequently assigned values, and the time delay does not exceed four sampling periods. The corresponding order of the upgraded sensor is given in tabular form. This makes it possible to find the required corrector without solving the shown equation in many cases. The effectiveness of the suggested approach with respect to improving the accuracy of digital sensors is shown by a numerical example. The zero error value of the upgraded sensor is confirmed both by computer simulation and numerical calculation. The results obtained can be used in the development of high-precision digital sensors of various physical quantities.
Hybrid Fungicides – An Easy Bridge to Trial of Biological Component for Improved Resistance Management and Better Crop Protection
Authors: Reuveni Moshe
Published: July 2023

The global search for plant-protection solutions that are both environmentally safe and effective is driven by the need to supply food to the ever-growing world population. The call for chemical load reduction is an important aspect for sustainable agriculture. Toxicity to non-target organisms and negative effects on human health by synthetic agrochemicals have led to a resurgence of interest in 'natural' means of pest and pathogen control, including new sources of biopesticides and botanical pesticides. In addition, there has been increasing pressure concerning the main challenges in crop protection, including better resistance management, regulatory demands, and consumer concerns. The control of plant diseases has depended increasingly on the extensive use of toxic pesticides. Inappropriate and prolonged applications of traditional chemical pesticides lead to environmental damage and adverse health effects. Furthermore, the extensive use of chemical pesticides led to the development of resistance to various plant pathogens. Therefore, improving resistance management is important. Also, consumers, including retail food chains, today demand healthier foods and more sustainable products with less chemical residue. Furthermore, an increasing number of governments and retail food chains have established strictly enforced chemical residue limits. If crops exceed these limits, they will not be allowed to enter these countries and retail food chains. However, there are several barriers to trial of biological products by growers, including the following: a). Biological products have a reputation for not working very effectively. Today there are many biological products that are as effective as synthetic chemicals, but the early impression from years ago remains among many growers, b) growers are very busy with current demands on their time, with most not having the time to learn new biology, reformulate their treatment regime, mixing and testing, and c) general resistance to change. Therefore, a new concept of 'hybrid products', as an easy bridge to trial biological component is suggested. Hybrid fungicides i.e., a combination of a natural product such as Tea Tree Oil (TTO) with broad-spectrum activity and a traditional site-specific chemical can be the 'bridge' between conventional agrochemical farming and sustainable farming. That is because it is a 'pre-mix' and is used in the same way as the grower's current chemical pesticide. Unlike other combinations based on two synthetic chemicals which in most cases have limited mechanisms of action, a premix with a botanical product provides multiple modes of action with an advantage for resistance management.
EN PRENSA. Evaluación microbiológica de recubrimientos a base de almidón extraído de frutos tropicales durante el almacenamiento postcosecha. EN PRENSA
Authors: Hernández-Guerrero Sara Elena , Balois Rosendo , López-Guzmán Graciela Guadalupe , Bautista-Rosales Pedro Ulises , Jiménez-Zurita José Orlando , López-Rivas Consuelo Esperanza
Published: July 2023

Los recubrimientos a base de almidón, además de poseer propiedades organolépticas, permiten el intercambio de gases. El objetivo fue evaluar la actividad microbiológica de recubrimientos a base de almidón extraído de frutos de plátano, mango y guanábana, aplicados a frutos de mango ‘Ataulfo’ estenospermocárpico durante su almacenamiento postcosecha. A partir de un lote de frutos de mango, se seccionaron segmentos de 1 cm2 de tejido, colocando en agar papa dextrosa e incubación por un periodo de siete días, haciendo selecciones de cepas. Se realizó una prueba de patogenicidad, inoculando los frutos con 10 µL de una suspensión de esporas de 1x10 -6 de cada una de las cepas previamente aisladas (ocho) asignándoles la nomenclatura CP (Cepa Patógena); seleccionando e identificando morfológicamente la CP de alta agresividad, evaluando los daños cualitativa y cuantitativamente. Se hizo una evaluación microbiológica (CP3) in vivo con frutos de mango ‘Ataulfo’ estenospermocárpico recubiertos con almidón al 2 % (p/v). Se observaron daños moderados (en frutos testigo) y ligeramente visibles en frutos recubiertos. El recubrimiento de mango inhibió el daño de CP3 en un 66 % hasta los ocho días de almacenamiento. Los recubrimientos a base de almidón de productos hortícolas coadyuvan a disminuir los daños ocasionados por microorganismos durante el manejo postcosecha.
Digital Space of Regions: Assessment of Development Factors and Influence on Socio-Economic Growth
Authors:   Institute of Economics, The Ural Branch of Russian Academy of Sciences, Akberdina Viktoria V. , Naumov Ilya V. ,   Institute of Economics, The Ural Branch of Russian Academy of Sciences, Krasnykh Sergey S. ,   Institute of Economics, The Ural Branch of Russian Academy of Sciences
Published: July 2023

The heterogeneity in the development of the digital space of Russian regions is due to the action of many factors related to the overall level of socio-economic well-being. The formation and expansion of digital space, too, has an impact on the socio-economic development of regions. The hypothesis of the study is an assumption that there is a two-way relationship between the digital space formed in the regions and the socio-economic indicators of their development. The purpose of the study is to identify the specifics of the formation of digital space in the regions, to assess the factors of its development and the cause-and-effect relationship with the indicators of socio-economic development of the territories. The article presents a methodological approach, the feature of which is the systematic use of methods of spatial autocorrelation analysis, methods of regression analysis on panel data and Granger causal relationship testing. As a result of this study, three groups of regions were identified according to the level of the development of digital space and the key factors of its development were identified. In the first group of regions, the high level of digital space development is due to the active use of advanced production technologies and a significant volume of GRP. In the regions of the second group, which included the leading production centers of the country, the development of the digital space is influenced not only by the economic condition of the territories, but also by their fiscal security. The development of the digital space in the regions of the third group, which are characterized by a weak level of the development of digital infrastructure and its use, is significantly influenced not only by the volume of the GRP produced and the budgetary provision, but also by the turnover of retail trade and the active use of advanced technologies. The study of cause-effect relationships using the Granger test allowed us to establish an inverse impact of the digital space on the socio-economic development indicators of the three groups of regions, thus confirming the hypothesis put forward. The used methodological approach and modeling results can be used to find optimal mechanisms for the development of the regions' digital space in order to ensure balanced socio-economic development.
Examining Tang and Song Yingtang image halls from a clan sacrificial perspective
Authors: Cheng Wanli
Published: July 2023

Abstract: During the Tang and Song Dynasties, the ordinary officials’ patriarchal clan gradually dominated the clan community. This phenomenon has destroyed the strict hierarchical sacrificial system. Therefore, as a new form of private sacrifice, the yingtang image hall appears in the ordinary officials’ residence or at ordinary people’s homes. At present, when a statue is replaced by an image, this new cultural symbol will lead every worshiper to reach social recognition psychologically and emotionally. Through the images or portraits hanging in the hall, the worshippers can confirm whether they can create a spiritual realm visually, so that they can communicate with their ancestors or tell their prayers.
The marxist philosophical basis of socialist literature and art
Authors: Liu Zijie
Published: July 2023

Abstract: Socialist literature and art are constructed on the basis of Marxist philosophy. The “people character” of socialist literature and art is based on the fact that Marxist philosophy abandons individualism and focuses on a wider population’s freedom and happiness. Therefore, socialist literature and art take people rather than individuals as the subject of expression. Realism, the basic principle of socialist literary and artistic creation, is based on the materialism of Marxist philosophy. The “typical environment and typical characters” proposed by Marxist classic writers for socialist literary and artistic creation are the method and principle formed by applying the philosophical concepts of the organic combination of the objective world and human subjectivity, and the organic combination of nature and social history to the concrete literary and artistic creation in Marxist theory. Marxist philosophy regards sensibility and aesthetics as important elements for literature and art to play a practical role. It believes that sensibility and aesthetics are not limited to the subjective world of people, but have the possibility of connecting with the external objective world. Therefore, socialist literature and art must pay attention to aesthetics.
Affective Relationships Among Siblings in a Situation of Institutional Care
Authors: Roque Ana Cristina Ferro , Silva Jonas Carvalho e , Penso Maria Aparecida
Published: July 2023

Abstract The purpose of this article is to identify the relationships of affection that exist between children/adolescents institutionalized in the same shelter. Data collection was carried out in two sisters hosted in Brasília-DF, through field notes, documentary analysis script, theme-story drawing, collage and semi-structured interviews. The indicators arouse from the results, which guided the organization of two of the sense zones, based on the methodology developed by Gonzalez Rey: a) The family of origin and the affective memories; b) Institutionalization and affection in the fraternal relationship. The importance of the sibling group was identified for the establishment of the sense of security, protection and pre-disposition for more positive and resilient attitudes.
Just World, Trust in Institutions and Socioeconomic and Political Moderations
Authors: Leal Tatiana Cavalcanti de Albuquerque , Lima Kaline da Silva , Pereira Cícero Roberto , Camino Leoncio
Published: July 2023

Abstract This study investigates the system justifying role through belief in a just world (BJW), testing whether institutional trust is related to this belief and whether this relationship depends on specific socioeconomic and political factors. A research with 381 university students, aged 18 to 64 years (M = 22.4, SD = 6.25), explored their BJW and their degree of institutional trust. Regression and moderation analyses revealed that BJW relates to institutional trust only in left-wing and with lower income participants. We believe this occurs because they need more an ideology that justifies the system to trust the institutions. This phenomenon can prevent these people from pursuing structural social changes since the system is now seen as fair.
Mundo Justo, Confiança nas Instituições e Moderações Socioeconômicas e Políticas
Authors: Leal Tatiana Cavalcanti de Albuquerque , Lima Kaline da Silva , Pereira Cícero Roberto , Camino Leoncio
Published: July 2023

Resumo Este estudo investiga o papel justificador do sistema através da crença no mundo justo (CMJ), testando se a confiança institucional está relacionada com essa crença e se esta relação depende de fatores socioeconômicos e políticos específicos. Uma pesquisa com 381 universitários, com idades de 18 a 64 anos (M = 22,4, DP = 6,25), explorou seus graus de CMJ e confiança institucional. Análises de regressão e moderação revelaram que a CMJ se relaciona com a confiança institucional apenas naqueles de esquerda e menores rendimentos. Acreditamos que isso ocorra porque estas pessoas precisam mais de uma ideologia justificadora do sistema para poder confiar nas instituições. Este fenômeno pode lhes indispor a buscar mudanças sociais estruturais, já que o sistema passa a ser visto como justo.
Programas de educação sobre saúde óssea para idosos: uma revisão integrativa
Authors: Ribeiro Emerson Moura , Silva Elzivânia de Carvalho , Sera Eduardo Aoki Ribeiro , Borges Thais Araújo , Dias Matheus Freire , Travassos Andreia , Osório Neila Barbosa , Silva Neto Luiz Sinésio
Published: July 2023

Resumo A osteoporose é uma doença sistêmica caracterizada pela redução da densidade mineral óssea. A difusão do conhecimento sobre à doença, pode ser uma alternativa viável para atitudes preventivas e de autocuidado. Dessa forma, esse artigo procura identificar como são os programas sobre saúde óssea para idosos. Trata-se de uma revisão integrativa de estudos publicados entre 2011 e 2022 nas bases de dados Periódicos Capes, Web of Science, PubMed e Google Scholar em inglês. Foram encontrados 10.093 estudos, sendo selecionados 7 depois dos critérios de inclusão. Foi possível verificar que os programas de educação para saúde óssea possuem o objetivo de empoderar o idoso pelo aumento do conhecimento sobre a doença, conscientizar sobre o consumo de cálcio e vitamina D ou de medicamentos para osteoporose, mudanças de hábitos e a prática de exercícios físicos. Os programas geralmente são realizados com reuniões em grupo ou individualizados, com sessões de 50 a 60 minutos, podendo ou não, delimitar o número de indivíduos em cada uma delas. Nota-se que acompanhar a evolução do processo educativo também é importante. A contextualização dos temas junto a realidade e interesse dos idosos, parece ser outra forma positiva para despertar atitudes de autocuidado.
Bone health education programs for older people: an integrative review
Authors: Ribeiro Emerson Moura , Silva Elzivânia de Carvalho , Sera Eduardo Aoki Ribeiro , Borges Thais Araújo , Dias Matheus Freire , Travassos Andreia , Osório Neila Barbosa , Silva Neto Luiz Sinésio
Published: July 2023

Abstract Osteoporosis is a systemic disease characterized by a reduction in bone mineral density. The dissemination of knowledge about the disease can be a viable alternative for promoting preventive behavior and self-care. This study sought to identify the main characteristics of bone health programs for older persons. We conducted an integrative review, searching for studies published between 2011 and 2022 in the CAPES periodicals database, Web of Science, PubMed, and Google Scholar using English descriptors. A total of 10,093 studies were retrieved, seven of which were selected after applying the inclusion criteria. The findings show that bone health education programs aim to empower older people by increasing knowledge about the disease and raising awareness about calcium and vitamin D intake, osteoporosis medications, and the importance of changing habits and exercise. Programs generally consist of group or individual meetings, with sessions lasting 50 to 60 minutes. Class sizes may be limited or unrestricted. Follow-up during the educational process was also found to be important. Tailoring topics to the reality and interests of participants appears to be another positive way of promoting the adoption of self-care practices.
Food consumption is associated with frailty in edentulous older adults: evidence from the ELSI-Brazil study
Authors: Ygnatios Nair Tavares Milhem , Lima-Costa Maria Fernanda , Torres Juliana Lustosa
Published: July 2023

Abstract This cross-sectional study aimed to evaluate the association between food consumption (meat, fish, and fruits and vegetables), anthropometric indicators (body mass index, waist circumference, and waist-to-height ratio), and frailty; and to verify whether these associations vary with edentulism. We used data from 8,629 participants of the Brazilian Longitudinal Study of Aging (ELSI-Brazil) (2015-16). Frailty was defined by unintentional weight loss, weakness, slow walking speed, exhaustion, and low physical activity. Statistical analyses included multinomial logistic regression. Of the participants, 9% were frail and 54% pre-frail. Non-regular meat consumption was positively associated with pre-frailty and frailty. Non-regular fish consumption, and underweight were associated only with frailty. Models with interactions reveled a marginal interaction between meat consumption and edentulism (p-value = 0.051). After stratification, non-regular meat consumption remained associated with frailty only in edentulous individuals (OR = 1.97; 95%CI 1.27-3.04). Our results highlight the importance of nutritional assessment, oral health, and public health-promoting policies to avoid, delay and/or reverse frailty in older adults.
Genealogical analysis of Quaternary Prevention: between the use of Evidence-Based Medicine and care reformulation in Primary Health Care
Authors: Andrade Henrique Sater de , Carvalho Sergio Resende
Published: July 2023

Abstract We conducted a genealogical analysis of quaternary prevention, an instrument of primary health care to address overmedicalization and iatrogenesis, based on related statements and interviews with the creators of this concept. This tool has been used in the reformulation of care and the doctor-patient relationship, but limited to the risk-benefit assessment by using current scientific evidence. In this study, we analyze the paradoxes of evidence-based medicine (EBM) and discuss the relationship of EBM and quaternary prevention and primary health care (PHC). Finally, we suggest questioning the truth of the evidence for the development of other health paradigms.
Food advertising aimed at children and adolescents in Brazil: a longitudinal analysis of denouncements in CONAR
Authors: Matos Juliana de Paula , Gondo Mariana , Mota Ludmylla Souza Elias , Horta Paula Martins
Published: July 2023

Abstract Scientific evidences show that self-regulation models fail to protect children and adolescents from commercial exploitation. In Brazil, the “Conselho Nacional de Autorregulamentação Publicitária - CONAR” is the entity that proposes guidelines for the products advertising and services to regulated sector. The aim is to analyze the denouncements of food advertising aimed at children and adolescents sent to CONAR between 2010 and 2020. The denouncements were described regarding the type of product and service, authorship (consumers/companies or CONAR), and CONAR decision (archiving/penalties). Descriptive and association analyzes were performed. Ninety-eight denouncements were identified, 74.8% of ultra-processed foods. There was an oscillation in the submission of denouncements over the years, with a general decline trend. Consumers were more frequent among the denouncements (58.6%) and 53.3% of total were penalty. Denouncements sent by CONAR or companies were more frequently penalized than those sent by consumers. There was a predominance of denouncements of advertisements for ultra-processed foods and low application of penalties. There was a lack of isonomy in CONAR decision pattern on advertisements.
Influência de padrões de multimorbidade nas atividades de vida diária da pessoa idosa: seguimento de nove anos do Estudo Fibra
Authors: Silva Diego Salvador Muniz da , Silva Marcela Fernandes , Assumpção Daniela de , Francisco Priscila Maria Stolses Bergamo , Neri Anita Liberalesso , Yassuda Mônica Sanches , Borim Flávia Silva Arbex
Published: July 2023

Resumo O objetivo foi avaliar a influência da multimorbidade e seus padrões nas atividades básicas de vida diária da pessoa idosa residente na comunidade. Trata-se de estudo de coorte com dados provenientes do Estudo FIBRA, linha de base (2008-2009) e seguimento (2016-2017). As atividades básicas de vida diária (ABVD) foram avaliadas pelo questionário de Katz e as doenças crônicas foram classificadas como (1) multimorbidade e padrões de multimorbidade: (2) cardiopulmonar; (3) vascular-metabólico; e (4) mental-musculoesquelético. Para a análise de dados, utilizou-se o teste qui-quadrado e a regressão de Poisson. Foram analisados 861 indivíduos sem limitação para ABVD na linha de base. As pessoas idosas com multimorbidade (RR = 1,58; IC95%: 1,19-2,10) e classificados nos padrões cardiopulmonar (RR = 2,43; IC95%: 1,77-3,33), vascular-metabólico (RR = 1,50; IC95%: 1,19-1,89) e mental-musculoesquelético (RR = 1,30; IC95%: 1,03-1,65) tiveram maior risco de apresentar declínio funcional nas ABVD no seguimento em comparação aos que não tinham os mesmos padrões de doenças. A multimorbidade e seus padrões aumentaram o risco de incapacidade na pessoa idosa ao longo de nove anos.
Avaliação das Instituições de Longa Permanência para Idosos no Brasil: um panorama das desigualdades regionais
Authors: Guimarães Mirna Rodrigues Costa , Giacomin Karla Cristina , Ferreira Raquel Conceição , Vargas Andrea Maria Duarte
Published: July 2023

Resumo O objetivo deste artigo é avaliar as Instituições de Longa Permanência para Idosos (ILPI) brasileiras, segundo o Modelo Teórico Multidimensional Integrado de Qualidade e Atendimento (MIQA), e comparar o desempenho alcançado entre as regiões do país. Estudo ecológico descritivo realizado com dados secundários públicos das ILPI participantes do Censo do Sistema Único da Assistência Social de 2018. Uma Matriz de Avaliação foi construída a partir das variáveis do Censo e do Modelo Teórico MIQA. Parâmetros de qualidade foram empregados para classificar o desempenho das instituições para cada indicador em “incipiente”, “em desenvolvimento” ou “desejável. O índice de disparidade foi obtido para cada indicador. Foram analisadas 1.665 instituições. Observaram-se diferenças nos percentuais de ILPI com desempenho “desejável” entre as regiões brasileiras, e a necessidade de aprimoramento na maioria das ILPI em relação à proporção de cuidadores de pessoas idosas, a composição da equipe multiprofissional, a acessibilidade e a oferta de ações de promoção de saúde. Verificou-se a necessidade de apoio governamental para a supressão dos critérios de diferenciações excludentes e para a expansão dos serviços para superar as superlotações.
Evaluation of Long-Term Institutions for Older People in Brazil: an overview of regional inequalities
Authors: Guimarães Mirna Rodrigues Costa , Giacomin Karla Cristina , Ferreira Raquel Conceição , Vargas Andrea Maria Duarte
Published: July 2023

Abstract This article aims to evaluate the Brazilian Long-Term Institutions for Older People (LTIE), according to the Integrated Multidimensional Theoretical Model of Quality and Service (MIQA), and compare the performance achieved between the regions of the country. Descriptive ecological study carried out with public secondary data from the LTIE participating in the 2018 Census of the Unified Social Assistance System. An Evaluation Matrix was constructed from the Census variables and the MIQA Theoretical Model. Quality parameters were used to classify the institutions’ performance for each indicator as “incipient”, “developing” or “desirable”. The disparity index was obtained for each indicator. 1,665 institutions were analyzed. Differences were observed in the percentages of LTIE with “desirable” performance between Brazilian regions, and the need for improvement in most LTIE in relation to the proportion of caregivers of older people, the composition of the multidisciplinary team, accessibility and supply of health promotion actions. There was a need for government support for the suppression of exclusionary differentiation criteria and for the expansion of services to overcome overcrowding.
O cuidado na casa de parto e sua conformidade com as diretrizes nacionais
Authors: Medina Edymara Tatagiba , Mouta Ricardo José Oliveira , Silva Sandra Cristina de Souza Borges , Gama Silvana Granado Nogueira da
Published: July 2023

Resumo O objetivo deste artigo é analisar a conformidade do cuidado oferecido pela Casa de Parto David Capistrano Filho-RJ às recomendações das Diretrizes Nacionais de Assistência ao Parto Normal. Estudo transversal descritivo com 952 observações, no período de 2014 a 2018. Análise de conformidade através de matriz de julgamento e classificada como conformidade total (≥75,0%), conformidade parcial (50,0%-74,9%), conformidade incipiente (49,9%-25,0%) e não conformidade (menor que 24,9%). Os resultados da matriz de julgamento mostram que o cuidado na atenção ao trabalho de parto, parto e assistência ao recém-nascido apresenta conformidade total em relação às recomendações das Diretrizes. O cuidado na Casa de Parto, conduzido por enfermeiras obstétricas, segue as recomendações das diretrizes nacionais, e vem evidenciando uma prática desmedicalizada, autônoma, que respeita a fisiologia do parto. Desenvolvem também um modelo de tecnologias próprias de cuidar, constituindo as tecnologias não invasivas de cuidado de enfermagem obstétrica.