bluuebunny/crossref_metadata_2025 huggingface dataset:
Some morphological aspects of myocardial bridges
Authors:   International Hospital Medpark, the Republic of Moldova, Tasnic Mihail , Catereniuc Ilia ,   Nicolae Testemitanu State University of Medicine and Pharmacy
Published: May 2021

Background: Myocardial bridges are variants of the intramyocardial position of the coronary arteries. In the specialty literature, hot topics in cardiovascular field are myocardial infarction and non-obstructive coronary artery disease with frequent connection with myocardial bridges. Material and methods: The morphological study was based on the analysis of 200 human hearts and fragments of coronary arteries. The retrospective study was focused on the analysis of 6168 coronary angiography reports, to identify patients with myocardial bridges, their preferred location, the degree of systolic stenosis, the association between myocardial bridges and proximal to bridge and under the bridge coronary atherosclerosis. Results: The complete myocardial bridges were described in 62% of the analyzed hearts and only in 5.3% of the total number of studied coronarographies. In the majority of cases, the complete myocardial bridges covered the anterior interventricular branch. The degree of subpontine arterial systolic stenosis varied within 10-95%. The comparative study did not determine any correlations between the degree of subpontine vascular compression and the degree of the left ventricular myocardial hypertrophy. In 32% of cases were described proximal to bridge atherosclerotic plaques and only in one case (0.5%) – distal to bridge atherosclerotic plaques, located immediately under the bridge. Conclusions: The research findings underline the differences in anatomical and angiographic incidence of myocardial bridges, and the inability of all bridges to reduce the lumen of under bridged artery. Current study emphasizes attention to the topography of bridges, the correlation with ventricular hypertrophy and coronary atherosclerosis.
Pengembangan Cerita Bergambar Bahasa Jawa (Cergam Baja) Untuk Siswa Sekolah Dasar
Authors: Mufidah Ulfa Miftakhul , Widiastuti Sripit , Riana Desy Dwi
Published: May 2021

Pembelajaran bahasa Jawa di sekolah mempunyai peranan sangat penting dalam membentuk sikap dan pribadi siswa, karena dalam belajar bahasa Jawa siswa mengerti bagaimana menggunakan unggah-ungguh bahasa yang baik dan benar kepada orang yang lebih tua. Berdasarkan analisis kebutuhan dan wawancara menunjukkan bahwa dalam pembelajaran bahasa Jawa siswa kurang memahami cerita Jawa, siswa kurang memahami isi cerita karena penggunaan bahasa dalam cerita tersebut adalah bahasa standar. Kebanyakan sekolah juga hanya menggunakan buku Tantri Basa, bukan buku yang dapat menarik perhatian siswa. Penelitian ini bertujuan untuk menghasilkan produk buku bergambar bahasa Jawa (Cergam Baja) yang sesuai untuk pembelajaran bahasa Jawa. Jenis penelitian yang digunakan adalah RnD yang dikembangkan oleh Sugiyono dengan tujuh tahap. Instrumen yang digunakan dalam penelitian ini adalah angket, hasil validator kelayakan ahli cerita sebesar 86%, ahli bahasa 89,3%, dan ahli materi ajar 88,3%. Hasil angket keterbacaan guru buku bergambar bahasa Jawa (Cergam Baja) diperoleh persentase 95,5% dan hasil angket keterbacaan siswa diperoleh persentase 96%. Berdasarkan hasil secara keseluruhan dapat disimpulkan bahwa buku Cergam Baja layak untuk digunakan sebagai bahan ajar
Penerapan Virtual Reality Sebagai Media Pengenalan Batik
Authors: Hanugrah Rayyan , Putri Devi Afriyantari Puspa
Published: May 2021

Batik adalah kain bergambar yang pembuatannya secara khusus, yang mana oleh UNESCO telah ditetapkan sebagai Warisan Kemanusiaan untuk Budaya Lisan dan Nonbendawi sejak 2 Oktober 2009. Pembuatan aplikasi ini bertujuan untuk memberikan pengetahuan mulai dari motif – motif Batik, filosofi sejarah setiap motif, cara pembuatannya serta untuk melestarikan kebudayaan Batik itu sendiri. Metode yang digunakan untuk mengembangkan sistem berbasis aplikasi Android adalah dengan metode SDLC (System Development Life Cycle) dengan proses pendekatan waterfall yang diawali analisa kebutuhan hingga proses pemeliharaan sistem. Pengembangan sistem ini memerlukan beberapa software pendukung, yaitu Sistem Operasi Windows 10 64Bit, Blender, Unity, Visual Studio Code, Android SDK, Google Cardboard SDK, bahasa pemrograman C#, CorelDraw X8, dan Ringtone Maker. Penelitian ini menghasilkan aplikasi Museum Batik Danar Hadi VR berbasis Android yang mana didalamnya terdapat fitur-fitur antara lain menu Museum VR, Permainan Tebak Motif Batik, Daftar Motif Batik beserta keterangan Batik, Petunjuk, dan Tentang. Berdasarkan hasil Black Box Testing, fitur dalam sistem dapat berfungsi sebagaimana mestinya. Kemudian, Usability Testing dengan metode SUS memperoleh skor rata-rata 75,5 menunjukkan hasil yang Baik dan Dapat diterima. Maka dapat disimpulkan bahwa sistem ini dapat memberikan informasi dan pengetahuan terkait Batik mulai dari motif – motif batik, filosofi sejarah, hingga cara pembuatannya serta untuk melestarikan kebudayaan batik yang merupakan salah satu warisan budaya paling mendalam di Indonesia yang diakui dunia.
Cultivo de palma fertirrigada com água residuária em sistema agroflorestal.
Authors:   ,   Universidade Federal de Campina Grande / Centro de Desenvolvimento Sustentável do Semiárido, Oliveira Ladna Naftaly Rodrigues de
Published: May 2021

A utilização de esgoto doméstico tratado na agricultura tornou-se uma das opções viáveis para reduzir a poluição das águas, reunindo um conjunto de vantagens para a sociedade e colaborando para a redução de impactos ambientais por ser uma solução mitigadora à poluição dos corpos hídricos. A tecnologia de reúso, confere um dos pontos para assegurar a disponibilidade e gestão sustentável da água e saneamento para todos (um dos Objetivos do Desenvolvimento Sustentável – Agenda 2030 – ONU). O uso de efluentes tratados de esgoto doméstico podem suprir a demanda hídrica de cultivos agrícolas e garantir, em parte, importante aporte nutricional para as plantas. Assim, objetivou-se avaliar a aplicação de esgoto doméstico tratado no cultivo de palma forrageira sobre os parâmetros biométricos fenológicos na região do semiárido paraibano. O experimento foi conduzido em campo na área experimental, localizada na sede do Instituto Nacional do Semiárido (INSA), no município de Campina Grande, em um arranjo experimental de blocos casualizados, com 08 repetições, 03 espécies vegetais e 03 tratamentos, correspondentes ao tipo e volume de água utilizada (T1 = 125 ml de água chuva, T2 = 125 ml de água residuária – AR, T3 = 250 ml de água residuária). A lâmina de irrigação aplicada de 2 L h-1 dia-1 semana-1 em sistema de gotejo. Foi instalado um sistema agroflorestal consorciado com 1560 raquetes de palma forrageira: Orelha de elefante mexicana (Opuntia stricta Haw) e 195 mudas de 2 espécies florestais: Sabiá (Mimosa ceasalpinifolea Benth) e Aroeira-Branca (Myracrodruon Urundeuva Allemão), plantadas em fila dupla. Entre os meses de agosto de 2019 a fevereiro de 2020, foram realizadas as avaliações biométricas na palma: altura da planta, número total de cladódios, perímetro espessura, comprimento e largura do cladódio. Cada cladódio avaliado e as plantas úteis foram identificadas (08 plantas por bloco). Sendo que em cada planta útil, apenas 01 raquete de palma foi monitorada. Os resultados obtidos foram submetidos análise de variância e as médias ao teste Tukey ao nível de 5% de significância e os contrates foram analisados por análise univariada ambos utilizando o programa estatística. Os tratamentos que receberam água residuária apresentaram maior desenvolvimento da planta. No entanto, o volume de água ofertado tem pouco efeito sobre as morfogêneses da planta. Em relação as propriedades químicas do solo a água residuária mostra-se existir uma influência positiva sobre o pH e matéria orgânica do solo.
Detailed Studies of Radiogalaxy Mrk1032
Authors: Hakopian S. A. , Dodonov S. N. , Andreasyan R. R.
Published: May 2021

The first results of the observations of Mrk1032, conducted with the 6-m telescope of SAO Russia, are given. It is shown, in particular, that a large complex of HII-regions, revealed by the integral-field spectroscopy, is the main source of UV radiation in the galaxy.
Stellar spectra analysis of giant stars: ARCTURUS
Authors: Rah Maria
Published: May 2021

In this study, we analyzed the evolved red giant ARCTURUS using high-resolution spectroscopy that was taken by HARPS. The other names of this star is α Boo - Arcturus - HR 5340 - HD 124897 - HIP 69673. This evolved (log g = 1.66 dex) star shows low metallicity nature ([Fe/H] = -0.52), which could be employed to study the chemical evolution of the early universe.
From Evolved Stars to the Formation and Evolution of NGC 6822
Authors: Aghdam Sima Taefi , Saremi Elham , Javadi Atefeh
Published: May 2021

NGC6822, an isolated dwarf irregular galaxy (dIrr), due to close distance, apparent isolation, and easy observation, has been always selected as a desired candidate for studying star formation and galactic evolution, without the strong gravitational influences of other systems. To derive the SFH of NGC6822, the method mentioned by Javadi et al. (2011) is used which is based on theoretical models coupled with color-magnitude diagrams (CMDs) by using directly the long period variable (LPV) stars which are mostly asymptotic giant branch (AGB) stars at their very late stage of evolution, as well as more massive red super-giant (RSG) stars according to their significant role to study the star formation rate (SFR). To calculate the SFH in the bar of the galaxy, we use more than 600 LPV stars from different catalogs of variable stars that two of the most important are Whitelock et al. (2013) and Letarte et al. (2002) that they reported the main part of the LPVs and the Carbon stars, respectively, Patrick et al. (2015) announced the RSG stars. Understanding the star formation history of NGC 6822 plays an important role in comparing the galaxy history evolution with other nearby dwarf galaxies as well as studying the nature of the evolving population of galaxies which were detected in deep redshift surveys.
TÜRKİYE’DE HEMŞİRELİKTE PROFESYONELLİK HAKKINDA YAPILMIŞ LİSANSÜSTÜ TEZLERİN ÇEŞİTLİ DEĞİŞKENLER AÇISINDAN İNCELENMESİ
Authors: COŞKUN Filiz , YILDIRIM Aytolan
Published: May 2021

Bu çalışmada Türkiye’de hemşirelikte profesyonellik hakkında yapılan doktora ve yüksek lisans tezlerinin incelenmesi amaçlanmıştır. Tanımlayıcı tipteki çalışmanın verileri, Yüksek Öğretim Kurulu (YÖK) Ulusal Tez Merkezi’ne kayıtlı tezlerden elde edilmiştir. YÖK Ulusal Tez Merkezi’nde detaylı arama sayfasında tez adı kısmında “profesyonel” anahtar kelimesi ve konu bölümünde “hemşirelik” seçilerek taranan lisansüstü tezler araştırmanın evrenini (n=85) oluşturmuştur. Araştırmacılar tarafından belirlenen dahil etme ve dışlanma kriterleri sonucunda; 4 doktora, 46 yüksek lisans tezi çalışma kapsamına alınmıştır. Veriler değerlendirilirken tanımlayıcı istatistikler kullanılmıştır. Türkiye’de hemşirelik alanında profesyonelleşme hakkında yapılan tezler 2005-2020 yılları arasındadır ve % 66’sı 2015 yılı sonrasında yapılmıştır. Tezlerin %54’ünün tanımlayıcı tipte, doktora tezlerinin ise %50’sinin deneysel tipte olduğu ve araştırmaların hepsinin nicel araştırma tipinde yapıldığı tespit edilmiştir. Tezlerin örneklem gruplarına bakıldığında, örneklemlerin %86’sının hemşirelerden oluştuğu görülmüştür. Niceliksel veriler kadar nitel verilerin de analiz edildiği tezlerin yapılması ve bu alanda az sayıda olan doktora tezlerinin planlanması önerilmektedir. Bu tezlerden elde edilen bilgilerin hemşirelik mesleğinin profesyonelleşmesıne katkı sağlayacağı düşünülmektedir.
AN ASSESSMENT OF THE STIGMATIZATION OF SCHOOL COUNSELING SERVICES IN DEVELOPING COUNTRIES
Authors:   Indiana University South Bend, Larrier Yvonne , Ratner Valerie ,   Indiana University South Bend
Published: May 2021

Developing countries are a primary focus in evaluating global mental health. The field of school counseling has the potential to act as the bridge between mental health needs and the delivery of evidence-based support. Research efforts to evaluate the underdevelopment and underutilization of mental health services in developing countries may assist in reducing stigmatization of counseling services, and subsequently promote the advocacy of culturally specific needs (Raney & Çinarbas, 2005). Stigmatization of mental health services is proposed as a hindrance in the development of school counseling programs. Researchers aim to decrease stigma in both community and school settings in the advocacy of students in developing countries. Efforts to investigate societal beliefs and stigmatization include analysis of general community, administrative, and teacher perspectives (Stockton & Güneri, 2011; Ibeziako, Omigbodun, & Bella, 2008). Ibeziako et al. (2008) argues that “despite evidence on the prevalence of child mental health problems and disorders in developing societies, there has been limited research on how these problems are perceived…”. The literature review at hand aims to provide an assessment of research on perceptions of mental health in developing countries in relation to school counseling services. The research collected places emphasis on the analysis of developing countries’ counseling training resources, school counseling identity, perception of mental health issues, and implications in culturally-sensitive counseling development.
SOCIO-ECONOMIC IMPEDIMENTS TO WOMEN DEVELOPMENT AND EMPOWERMENT IN PESHAWAR, KHYBER PAKHTUNKHWA
Authors:   Planning and Development Department Khyber Pakhtunkhwa, Peshawar, Bibi Saadia , Kalhoro Zulfiqar Ali ,   Department of Development Studies, Pakistan Institute of Development Economics, Islamabad
Published: May 2021

Pakistan stands among the worst performers when it comes to the equal opportunities for women. The Sustainable Development Goals (2015-30) have rightly prioritized women’s empowerment to provide them with equal opportunities. The empowerment of women brings about significant positive changes in the socio-economic aspects of the family and women’s status. The patriarchal nature, socio-cultural conditions and feudalistic mode of fabrication in Pakistani society has always kept women marginalized and have restricted them to participate along-with men in communal activities. This study was conducted in Peshawar Khyber Pakhtunkhwa. At the first stage, a purposeful sampling technique was applied, and then convenience sampling was used for final data collection. The data was collected through a semi-structured interview guide, Students, government staff and employees of private organizations were involved. The study shows that socio-cultural factors have significant implications for the development of gender and empowerment of women. Keywords: women development, women empowerment, culture and religion, women and culture
TEACHERS’ PERCEPTIONS AND PRACTICES OF ASSESSMENT RUBRICS IN ASSESSING STUDENTS’ LEARNING AT HIGHER EDUCATION LEVEL
Authors:   Department of Educational Development Karakoram International University, Abbas Ghulam , Qutoshi Sadruddin Bahadur ,   Department of Educational Development Karakorum International University, Angaiz Dil ,   Department of Educational Development Karakorum International University
Published: May 2021

This study aims to explore teachers’ perceptions and practices of the use of rubrics in assessing students’ learning in the context of higher education institutions in Gilgit-Baltistan. A case study method of inquiry within a qualitative paradigm was adopted to collect the relevant data through semi-structured interviews from three purposefully selected teacher-educators (instructors) and six student-teachers (prospective teachers) of semester III and IV from one of the colleges of education. The data were analyzed through thematic analysis and following themes were emerged: (1) the importance of assessment rubrics in teaching and learning processes, (2) effectiveness of rubrics in assessing teaching and learning, (3) coconstruction of assessment rubrics by student-teachers and teacher-educators, and (4) the challenges for student-teachers and teacher-educators in developing and using of assessment rubrics. From the discussion on the emerging themes, it is concluded that (a) use of assessment rubrics makes assessment process more meaningful to both teacher-educators and students-teachers; and (b) use of rubrics makes student-teachers and teacher-educators more focused on their purpose of teaching and learning outcomes. It is recommended that teacher-educators in teacher training institutions should use rubrics to assess prospective-teachers so that they, after completing their degree programs, would use similar techniques in their respective schools to assess their students’ learning outcomes effectively. Keywords: Assessment, Assessment Rubrics, Rubric Design, Teaching and Learning.
UNDERSTANDING THE LEVELS OF SATISFACTION AMONG UNIVERSITY STUDENTS ABOUT THE USE OF ICTS
Authors:   Department of Sociology, Quaid-i-Azam University, Islamabad, Abbas Ali , Mehmood Sana ,   Department of Sociology & Anthropology, Karakoram International University, Gilgit, Bibi Saadia ,   Gender and Learning Specialist, Planning and Development Department Khyber Pakhtunkhwa, Peshawar
Published: May 2021

The aim of this study was to understand the satisfaction levels of undergraduate students of Quaid-i-Azam University (QAU), Islamabad about the usage of Information and Communication Technologies (ICTs) for their academic purposes. The quantitative research approach was applied to collect data through a survey method from two hundred (200) sampled respondents from three faculties of QAU i.e., social science, natural science, and biological sciences. The convenient sampling technique was used for the selection of the respondents. A well-structured questionnaire was used for the survey purpose. Some of the questionnaires were self-administered while the rest were distributed among the respondents and collected later. The data were analyzed in Statistical Package for Social Science (SPSS) and both descriptive and inferential statistics were applied. The findings of the study showed that undergraduate students at QAU were using the internet, having sufficient knowledge of ICTs, and were using these ICTs for educational purposes, such as research work, class assignments, and communication with teachers. The Confidence Interval was [95% and MoR was 0.05). All the figures had less than 0.05 values which means the variables are correlating to each other. Some of the respondents stated that there is a lack of ICTs well-trained staff and limited space in the computer laboratories at the campus. The university administration should pay special attention to the provision of ICTs to the student so that they could get maximum benefits out of it. Moreover, the respondent’s knowledge about the usage of ICTs has a strong relationship with the students’ attitude towards the ICTs use. The respondent’s level of knowledge about the ICTs has a less likely effect on the major constraint in using ICTs. Keywords: Information and Communication Technologies, Quaid-i-Azam University, Cognitive Flexibility, Academic Activities, Internet, Pakistan
Design, Optimization and in vitro Characterization of Dasatinib loaded PLGA Nano carrier for Targeted cancer therapy: A Preliminary Evaluation
Authors: S Kumar Shyam , Gopalakrishnan G. , Gowrishankar N. L.
Published: May 2021

Objective: Drug nanoparticles offer a versatile platform for enhancing the dissolution rate and bioavailability of poorly water soluble drugs The present study was aimed to design and develop dasatinib (DAS) loaded Poly lactide co glycolic acid (PLGA) to enhance the dissolution rate and to study the effect of formulation variables for the BCS class II drug dasatinib for the treatment of chronic myeloid leukemia. Methods: The DAS loaded Nps were prepared by using modified double emulsion solvent evaporation method (DESE) using different stabilizers, the formulated Nps were characterized for particle size, zeta potential, Poly Dispersity Index, Surface morphology, Drug entrapment and Invitro drug release. Results: The DAS loaded NP s showed the lowest particles size of 123 nm and zeta potential of – results of Pluronic F68 loaded NP showed the lowest particle size of – and highest zeta potential of --. Surface morphology of NPs with DMAB showed distinct smooth spherical particles with the size range of 50nm. Morphology of Pluronic F68 formulated NPs showed the high degree of aggregation. In vitro drug release showed up to 24hrs in a sustained manner. Conclusion: The result of our study indicates the use of PLGA as a sustained release polymer and using DMAB as a stabilizer for better stable formulation.
Bioactivity guided extraction of PDHC [3,3’-(propane-2,2-diyl)bis(3,4,5,6,7,8- hexahydro-1h-isochromene)]: A Novel antibacterial compound from an ornamental plant Polyalthia longifolia
Authors: Segaran Gayathri , Ravi Lokesh , Sathiavelu Mythili
Published: May 2021

Objective: The objective of the study was to determine and compare the antibacterial effect of different ornamental plants and to isolate the effective bioactive compound with antibacterial activity from Polyalthia longifolia. Methods: Petroleum ether and methanol extracts of Bougainvillea glabra, Polyalthia longifolia, Ixora coccinea Linn. ,Plumeria rubra and Euphorbia milli leaves were investigated for antimicrobial activity by performing agar well difusion method. The plant extract with the highest antibacterial activity was selected and further used for the isolation of antibacterial compounds. In silico docking studies and in vitro antibacterial assay was performed to analyze the biological activity of pure compound. Results: The highest antibacterial activity was found in the pet ether of Polyalthia longifolia against all the tested bacterial strains and the extract was further selected for compound separation. A novel compound 3,3’-(propane-2,2-diyl)bis(3,4,5,6,7,8-hexahydro-1H-isochromene) (PHDC) with a molecular weight of 316.35 g/mol and molecular formula C21H32O2 was identified from Polyalthia longifolia by using spectroscopic studies. In the in vitro antibacterial assay, PHDC demonstrated significant antibacterial showed against Protease mirabilis. In silico docking studies revealed that PHDC showed antibacterial activity by inhibiting tRNA Synthetase (IleRS). PHDC exhibited the lowest binding energy of - 8.7Kcal/Mol for Isoleucyl tRNA Synthetase (IleRS), the protein responsible for protein synthesis. Conclusion: The emergence of multiple antibiotics resistant microbes has become huge nowadays and the infections caused by these resistant microbes cannot be treated with antibiotics. PHDC is a novel compound extracted from Polyalthia longifolia showed significant antibacterial effect and we suggest that the compound can be further used as lead molecules to overcome the infections caused by antibiotic resistant bacteria.
Preparation and Characterization of Novel Self Nano Emulsifying Drug Delivery System of Allopurinol
Authors: Patel Priyal , Solanki Shilpa , Mahajan Ashok , Mehta Falgun , Shah Kautuk
Published: May 2021

The aim of research was to develop self nanoemulsifying drug delivery technology containing low aqueous soluble drug allopurinol for improving solubility, dissolution and bioavaibility. Preliminary screening were carried on the basis of maximum solubility of allopurinol in oil, surfactant, co-surfactant and pseudo-ternary phase diagram was constructed to identify the ratio of surfactant and co-surfactant for nanoemulsion formulation using water titration method. Based on the solubility study, Labrafil M 1944 CS, Cremophor RH 40, Transcutol used as oil, surfactant, and co-surfactant respectively. Pseudo-ternary phase diagram was constructed to identify the ratio of surfactant and co-surfactant for nanoemulsion formation by water titration method. As per the ternary phase diagram ratio of Smix in 2:1 was identified with maximum emulsification area. SNEDDS composed of 35 % Labrafil M 1944 CS, 43.34% Cremophor RH 40, 21.66% Transcutol. Globule size was found to be 25.42 nm, and zeta potential value was -9.26 mV. Prepared SNEDDS were evaluated for globule size, viscosity, emulsification time, cloud point, dilution test and thermodynamic stability study. Prepared liquid SNEDDS then converted into solid SNEDDS via extrusion/spheronization technique using Aerosil 200, lactose monohydrate and Croscarmellose sodium. The pellets containing SNEDDS possessed good flow properties and mechanical strength and other rheological parameters. Self nanoemulsifying pellet exhibited uniform size and shape. Friability, dissolution time and disintegration of pellets formulation shown promising results. Time required for 80% drug release of self nanoemulsifying pellet was found to be 26 min, which was significantly lower than liquid SNEDDS, plain drug containing pellet and marketed preparation of Allopurinol (ZYRIK).
Synthesis, Characterization and Anticancer Evaluation of Novel Analogues of Pyrazoles
Authors: Khatun Babli , Kamath Venkatesh , B. S. Muddukrishna , Pai Aravinda
Published: May 2021

In the present study, a series of novel substituted pyrazole chalcones and pyrazole oximes (CF 1-15) were synthesized and characterized. Logp values were determined to assess their hydrophobicity. MTT (methyl tetrazolium) assay was performed on A-549 (lung cancer) cell lines. The MTT assay results showed the effect of various substituents on the pyrazole template that could influence their cytotoxic effect. Out of the 15 compounds screened against A-549 cell lines, the compound CF-6 showed appreciable cytotoxicity against the standard doxorubicin.
Anti-Candida activity of few India Medicinal herbs used in the treatment of Gynecological disorders
Authors: Shriwas Shweta , Chouksey Raju , Dwivedi Sumeet
Published: May 2021

Gynecological disorders are very frequent and common among Indian women due to various un-hygienic issues. As per Ayurvedic literature there are several herbs used to cure women disorders, though there proper documentation and validation need to be established. One of the major fungus causing gynecological infection is Candida species. It has increasingly deserved a special attention among the medical community. In spite of the presence of Candida species as a human commensal, alarming rates of local and systemic infections have been observed, varying from moderate to severe impact. The present work aims to investigate the anti-candida activity of hydroalcoholic extract of Achyranthes aspera Linn. (Roots) ASR, Clitoria ternatea Linn. (Roots) CTR, Ipomea cairica Linn. (Leaves) ICL and Plumeria pudica Jacq. (Leaves) PPL. The results obtained were compared with standard anti-fungal drugs amphotericin B. Further studies need to be establish to deepen knowledge on this area, namely, focused on clinical trials to provide safer and more effective anti-fungal than the current ones.
Anti-proliferative effects of Euphorbia hirta L on the activity of cytotoxicity in bone cancer MG-63 cells
Authors: Rajakumaran Subhashini , Christiya C Ruth
Published: May 2021

Medicinal plants maintain the health and vitality of individuals, and also have potential curative effect on various diseases, including cancer. Bone cancer is the foremost cause of deaths among women worldwide. In this present study, the antiproliferative effects of methanol extracts of Euphorbia hirta L leaves was investigated on MG 63 cell line. The methanolic extract of plant exhibited significant dose dependent antiproliferative activity against MG63 cell line which was ranged between 89.43% and 20.63% at concentrations of 50µg/ml and 350µg/ml correspondingly (24 hours). Moreover, the plant found to decrease the cell viability in dose dependent manner. The results of this study show that Euphorbia hirta L is a potential source of compounds that may serve as leads for anticancer property.
The Effect of Chitosan Addition in Acrylic Resin Matrix towards the Residual Monomers and Impact Strength
Authors: Ismiyati Titik , Ali Alhasyimi Ananto
Published: May 2021

Background: A residual monomer might have impact on the quality of acrylic resin since its caused allergic reactions and inflammation. Chitosan is a biocompatible material and potential to reduce residual monomers and ameliorate the impact strength of acrylic resin Objective of the study: To examine the effect of an acrylic resin matrix mixed with chitosan together with 1% and 2% acrylic acid as denture base and orthodontic material on residual monomers and impact strength. Methodology: There were 30 samples for the test analysis. The impact strength test sample formed with a plate size of 55 × 10 × 10mm, whereas the residual monomer test sample was prepared into powder. The test samples were divided into 3 groups, of 10 samples. Group 1 acrylic resin only, group 2 acrylic resin matrix mixed with chitosan and 1% acrylic acid, group 3 is the same as group 2 but with a concentration of 2% acrylic acid. Gas chromatography was used for measuring the residual monomers. The impact strength was tested by the Charpy impact. The data was evaluated using the ANOVA and correlation test. Results: There were significant differences (p < 0.05) in acrylic resin without addition with the matrix of acrylic resin with chitosan and acrylic acid 1% and 2% to the number of monomers and impact strength. Conclusion: The mixture of acrylic resin with chitosan and acrylic acid 1% and 2% can reduce the amount of residual monomer and increase the impact strength.
A Review: Comparison of Efficacy of Liraglutide Versus Sitagliptin add-on-to Metformin in Type 2 Diabetes Mellitus patients
Authors: Kavyasree A. , Geetha P. , Shanmugasundaram P.
Published: May 2021

Background: The aim of this review is to compare the efficacy of liraglutide versus sitagliptin add-on-to metformin in patients with Type 2 Diabetes Mellitus and inadequate glycemic control for rational use of drugs. Methods: We searched for randomized controlled trials (RCT) in MEDLINE, Web of science, PubMed, Cochrane library, CNKI, and Wanfang database and extracted data from all randomized controlled trials (RCTs) up to July 11, 2019 of liraglutide versus sitagliptin given in combination with metformin. RCTs were selected only if they were RCTs comparing DPP-4 inhibitor (sitagliptin) monotherapy to metformin monotherapy with the GLP-1 Receptor Agonists (liraglutide), duration of treatment was ≥26 weeks and reported data on hemoglobin A1c (HbA1c) change, fasting plasma glucose (FPG) change, Odds ratio (OR), mean difference (MD), 95% confidence interval are used to analyze the outcomes. Results: A total of 2,257 patients from 6 RCTs were included in the study. When compared with sitagliptin (100mg) in combination with metformin group, the group of patients treated with liraglutide1.2mg and 1.8mg and metformin, produced greater reduction in HbA1c, FBG. (95% CI). The group of patients with 1.8mg liraglutide had significant weight loss. The incidence of nausea, hypoglycemic episodes, gastrointestinal problems was higher than the sitagliptin with metformin groups. Conclusions: The results of this study indicated that the liraglutide – metformin combination therapy could significantly lower the HbA1c level and increased reduction of body weight. ADRs such as gastrointestinal problems, hypoglycemic episodes were common in liraglutide treatment group.
A Review on Deadly Nipah Virus - Prevalence and its Management
Authors: Mathew Therese , R Badmanaban. , Paul Aby , Mishra Bharat
Published: May 2021

NiV is an emerging infectious disease caused by infected bats from the family of Paramyxoviridae. From its secretions the disease can be spread to humans or through close contact with infected humans. NiV was detected for the first time in 1998 in Malaysia. NiV have broad species tropism and potential that may evolve life threatening respiratory and/ or neurologic disease in humans and as well as in animals which make them important trans-boundary biological threats. The disease presented mainly as acute encephalitis with a short incubation period of less than two weeks (4 to 18 days), with the main symptoms of fever, headache and giddiness followed by coma. The major involvement of the lung and brain in NiV infection often manifested as an acute severe respiratory syndrome, encephalitis etc. In case of Henipavirus the diagnosis of infection is mainly based on the details of contact with diseased animals, evidence of encephalitis and or pneumonia, with serologic evidence of infection using Enzyme Linked Immunosorbant (EIA) assay testing or polymerase chain reaction. The anti-viral drug Ribavirin is a well-known first line treatment strategy for suspected viral infections of unknown etiology. Based on a study conducted to discover whether combining monotherapeutic treatments with Ribavirin and Chloroquine would result in any protection indicative of favourable drug-drug interactions when treatment were initiated with lethal inoculums of NiV. The reason for multiple outbreaks may be due to low healthcare system capacity and robust surveillance strategy contributes to it. Multidisciplinary and multiple facet approach is vital in preventing the emergence of NiV. It is crucial to undertake rigorous research for developing vaccines and medicines to prevent and treat NiV.
Epidemiology, Risk, Myths, Pharmacotherapeutic Management and Socio- economic Burden due to Novel COVID-19: A Recent Update
Authors: Ahmad Sarfaraz , Shoaib Ambreen , Ali Md. Sajid , Alam Md. Sarfaraz , Alam Nawazish , Ali Maksood , Mujtaba Md. Ali , Ahmad Ayaz , Ansari Md. Salahuddin , Ali Mohammad Daud
Published: May 2021

The novel human coronavirus disease (COVID-19) is the major pandemic throughout the globe and its occurrence is due to the presence of severe acute respiratory syndrome coronavirus (SARS-CoV2). That began from Wuhan, Hubei province of China in late 2019 and afterward drastically spread worldwide. It effects around 213 countries and territories around the globe and have reported a total of 8,128,490 confirmed cases of COVID-19. As an unprecedented global pandemic it sweeps the planet and affects each and every human being either physically, mentally or economically. The most common symptoms of COVID-19 are pyrexia, tiredness, and dry cough but in some cases it is asymptomatic. It can be diagnosed by a health care provider based on symptoms and confirmed through laboratory tests. Till date there is not even a single drug or vaccine that can be used for the effective treatment for this disease. The international community is to introduce a global synchronized strength to prevent the outbreak that needs a strong public health response, high level political commitment and sufficient funding. The aim of this review article is to summarise the recent state of awareness, epidemiology and social impact on surrounding due to outbreak of COVID-19 pandemic.
Vận dụng phương pháp mô hình hóa trong giảng dạy học phần Đại số sơ cấp ngành Sư phạm Toán
Authors: Phạm Mỹ Hạnh
Published: May 2021

Toán học từ lâu đã có mối quan hệ mật thiết với mọi lĩnh vực của đời sống xã hội, nên dạy học toán cần giúp người học hiểu rõ và vận dụng toán học vào các bài toán thực tế. Một trong những phương pháp hiệu quả đáp ứng mục tiêu này là sử dụng mô hình hóa để nghiên cứu các sự vật và hiện tượng trong hoạt động thực tiễn. Dựa trên các tài liệu nghiên cứu về phương pháp mô hình hóa trong giảng dạy toán, bài viết sẽ trình bày các bước cần thiết của hoạt động dạy học toán bằng mô hình hóa, thông qua các ví dụ minh họa có liên quan đến nội dung của học phần Đại số sơ cấp ngành Sư phạm Toán.
Từ thực trạng đề xuất giải pháp nâng cao kỹ năng phòng tránh tai nạn đuối nước cho trẻ em ở vùng dân tộc thiểu số ở tỉnh Gia Lai
Authors: Nguyễn Tiến Dũng , Trần Văn Điện , Hoàng Việt Trung
Published: May 2021

Tai nạn đuối nước ở tỉnh Gia Lai trong thời gian gần đây không chỉ là vấn đề nhức nhối đối với mỗi phụ huynh và học sinh mà còn là vấn nạn của cả xã hội vào những dịp hè và mùa mưa lũ. Số ca tai nạn đuối nước của trẻ em ở tỉnh Gia Lai đứng thứ hai (sau tai nạn giao thông) và có số người tử vong đứng đầu trong trong bảng thống kê tai nạn thương tích của toàn tỉnh. Bằng phương pháp điều tra xã hội học và phương pháp thực nghiệm, thống kê, bài viết đã làm rõ thực trạng tại nạn đuối nước trẻ em ở tinh Gia Lai, đồng thời đánh giá một cách khách quan về nguyên nhân dẫn đến thực trạng trên cơ sở đó đề xuất giải pháp phù hợp góp phần giảm thiểu tình trạng tai nạn đuối nước trên địa bàn tỉnh Gia Lai.
Giải pháp nâng cao hiệu quả ứng dụng mô hình kế toán mô phỏng trong đào tạo kế toán tại Trường Cao đẳng Cộng đồng Đồng Tháp
Authors: La Ngọc Giàu
Published: May 2021

Bài viết mô tả các yếu tố cấu thành của phòng kế toán mô phỏng, ứng dụng phòng kế toán mô phỏng trong giảng dạy và kết quả đạt được. Bên cạnh đó, bài viết cũng đưa ra một số điểm còn hạn chế thuộc về phòng kế toán mô phỏng, hạn chế trong công tác đào tạo ngành kế toán tại Trường Cao đẳng Cộng đồng Đồng Tháp, từ đó đưa ra một số giải pháp nhằm sử dụng hiệu quả phòng kế toán mô phỏng trong giảng dạy, nâng cao chất lượng đào tạo chuyên ngành kế toán.
Quản lý hoạt động bồi dưỡng giáo viên các trường mầm non trên địa bàn thành phố Quy Nhơn, tỉnh Bình Định theo Chuẩn chức danh nghề nghiệp
Authors: Võ Nguyên Du , Đặng Thị Thanh Thuý
Published: May 2021

Mục tiêu giáo dục mầm non giúp trẻ em phát triển về thể chất, tình cảm, thẩm mĩ để hình thành những yếu tố đầu tiên của nhân cách trẻ. Mục tiêu này được trao cho đội ngũ cán bộ quản lý và giáo viên cơ sở giáo dục mầm non thực hiện; vì vậy, tăng cường xây dựng đội ngũ giáo viên và cán bộ quản lý ở các trường mầm non một cách toàn diện theo hướng chuẩn hóa là nhiệm vụ vừa đáp ứng yêu cầu trước mắt, vừa mang tính chiến lược lâu dài. Bài viết trình bàythực trạng quản lý hoạt động bồi dưỡng giáo viên các trường mầm non tại thành phố Quy Nhơn, tỉnh Bình Định theo Chuẩn chức danh nghề nghiệp và đề xuất một số biện pháp quản lý hoạt động này tại địa phương.
Chế tạo vật liệu hydrogel tổ hợp của nanocellulose và alginate hướng đến ứng dụng trong xử lý nước thải dệt nhuộm
Authors: Vũ Năng An , Võ Thị Hồng Hoa , Lê Văn Hiếu
Published: May 2021

Trong báo cáo này, chúng tôi tổng hợp vật liệu hydrogel hấp phụ có khả năng tái tạo trên cơ sở nanocellulose và alginate. Nanocellulose tổng hợp từ cellulose, được cô lập từ bã mía, bằng phương pháp thủy phân axit. Phân tích kết quả TEM cho thấy nanocellulose tổng hợp có dạng sợi với tỷ lệ L/D cao. Vật liệu hydrogel giữa nanocellulose và alginate được tổng hợp bằng quá trình gel hóa ion với sự hiện diện của ion Ca2+. Hydrogel (nanocellulose và alginate) thu được có dạng hình cầu, được khảo sát khả năng hấp phụ methylene blue khi thay đổi các điều kiện như: nồng độ chất nhuộm, thời gian hấp phụ và lượng chất hấp phụ. Hydrogel cho thấy khả năng hấp phụ methylene blue tốt hơn so với alginate thuần.
The effect of applying “Small talk as warming-up technique” in EFL classrooms on students’ improvement in English speaking skill
Authors: Nguyen The Binh
Published: May 2021

So far junior high school students have dealt with obsolete English speaking topics in textbooks developed by the MOET. They are often fed up with speaking lessons, and thus their speaking skill fails to improve after many years studying English at school. Stimulated by this reality, the current study was carried out to investigate the effect of applying “small talk as warming-up technique” in EFL classrooms on students’ speaking skill improvement. A schedule of applying “small talk as warming-up technique” in English language classrooms was developed; then a training program with seventeen appropriate topics aside from the prescribed curriculum of “Tiếng Anh 9” by the MOET was conducted. Within a term of nearly four months, the results have showed that, after the treatment, students’ achievement was proved to be significant in improving English speaking skill.
Production Optimization for Natural Flow and ESP Well A Case Study on Well NS-5 Mishrif Formation-Nasriya Oil Field
Authors: Abdulameer Hamzah Amer , Hamd-Allah Dr. Sameera
Published: May 2021

As the reservoir conditions are in continuous changing during its life, well production rateand its performance will change and it needs to re-model according to the current situationsand to keep the production rate as high as possible.Well productivity is affected by changing in reservoir pressure, water cut, tubing size andwellhead pressure. For electrical submersible pump (ESP), it will also affected by numberof stages and operating frequency.In general, the production rate increases when reservoir pressure increases and/or water cutdecreases. Also the flow rate increase when tubing size increases and/or wellhead pressuredecreases. For ESP well, production rate increases when number of stages is increasedand/or pump frequency is increased.In this study, a nodal analysis software was used to design one well with natural flow andother with ESP. Reservoir, fluid and well information are taken from actual data of Mishrifformation-Nasriya oil field/ NS-5 well. Well design steps and data required in the modelwill be displayed and the optimization sensitivity keys will be applied on the model todetermine the effect of each individual parameter or when it combined with another one.
نظام التامين في عقود جولات التراخيص و سوق التامين العراقي
Authors: محمد بشرى رضا
Published: May 2021

من أجل تنشيط سوق التأمين العراقي وإعادة تأهيله ليواكب التطور الحاصل في هذا المجال بعد الانقطاع الطويل عن سوق التأمين الدولي، تطلب الأمر إعادة دراسة للقوانين العراقية وتغير ممارسات أعمال التأمين، فعمدت الدولة إلى وضع خطط  لجذب رؤوس الأموال والاستثمارات لتنفيذ المشاريع في العراق من خلال تشريع قانون تنظيم أعمال التأمين رقم (10) لسنة 2005 الذي فتح الابواب لشركات التأمين الاجنبية العمل في العراق فأصبحت تلك الشركات تنافس الشركات المحلية والشركات الوطنية كما سمحت عقود جولات التراخيص للمقاول والمشغل والمقاول الثانوي الحصول على تغطية تأمينية من شركات محلية أو أجنبية بموجب القانون المذكور.
Geological Model for Khasib Formation of East Baghdad Field Southern Area
Authors: Jameel Layth A. , Kadhim Fadhil S. , Al-Sudani Hussein Ilaibi
Published: May 2021

Geological model construction is an important phase of reservoir study as the production capacity of a reservoir depends on its structural and petrophysical characteristics. The economic benefit of the reservoir is evaluated by estimating the formation petrophysical properties and calculating the oil reserves. East Baghdad southern area field is a newly developing oil field in the middle region of Iraq, where Khasib formation is its main reservoir. The aim of this study is to estimate the petrophysical properties and determine the pay units of the formation under study and the initial oil in place. Sequential Gaussian Simulation was used here to distribute the petrophysical properties as the statistical method and volumetric method was used to calculate the oil in place. The results show that the main reservoir units of the formation are K2 and K3 units, and the estimated oil reserves equal to 2179 mmSTB (346.43 million cubic meters).
Using Nanomaterials in Stabilization of Soil for Oil Infrastructures
Authors: Majeed Dr. Zaid Hameed , Aubais Eng. Kadhim Jawad , Taha Dr. Mohd Raihan
Published: May 2021

The design foundations  of storage tanks for oil industry experiences significant problems due to the widespread occurrence of weak and compressible soil which resulted in foundation failure. In this study, soft soils were taken from two locations and mixed with three types of nanoparticles which were nano-alumina (nano Al2O3), nano-copper (nano CuO), and nano-magnesium (nano MgO). Nanomaterials were incorporated in small percentage (less than 1%) by dry weight of soil. The tested geotechnical characteristics included the water content, dry density, and the unconfined compressive strength. The results showed significant enhancements in the maximum dry density and unconfined compressive strength. The level of enhancement depended on the type of nanomaterials and the contents. Improved strength and hardening properties were shown with the utilization of nano CuO material in comparison to the soil samples with the other nanomaterials additions, with its optimum addition of 0.7% provided an increment rate of 662.7% while the optimum nano CuO which is about 1% showed a 532% increasing rate in the compressive strength of S1 soil. It was noted that the maximum dry density and unconfined compressive strength enhanced with the increase in the nanoparticles content until reaching a percentage in which the strength decreased. The optimum content of the nano MgO was 0.3% while the optimum nano Al2O3 content was about 0.3% for soil S1 and was about 0.1% for soil S2. The presence of nanomaterials in excessive contents caused agglomeration of particles which had negative influences on mechanical characteristics of the soils. Generally, the incorporation of finer particles like nanoparticles even with low amount would improve the geotechnical characteristics of soils with the consideration of the potential environmental benefits, these combined admixtures are intended to lower the cost and become a more sustainable and environmental alternative for soil stabilization
Iraq Crude Oil Exports – January, February, March 2019
Authors: / Oil Marketing Company Ministry of Oil
Published: May 2021

Table 1. Iraq Crude Oil Exports – January 2019Table 2. Iraq Crude Oil Exports – February 2019Table 3. Iraq Crude Oil Exports – March 2019
Damage sensing and mechanical properties of a laminate composite material containing MWCNTs during low-velocity impact
Authors: Al-Bahrani Mohammed , Alhakeem Mohammed Ridh H. , Cree Alistair
Published: May 2021

In this work, we present a new criterion, unlike other attempts, to evaluate and quantify the degree of damage of composite material when it subjected to a sudden impact load. Our criterion exploits the high intrinsic electrical conductivity property of the Multi-walled carbon nanotubes (MWCNTs) after dispersing different concentrations of them (0, 0.5, 1.0, 1.5 and 2.0 %) in the epoxy matrix of a glass fibre composite. Following this goal, the low-velocity impact and flexural after impact (FAI) tests on the MWCNTs-glass epoxy (i.e. MWCNTs-GF) nanocomposite were evaluated. At the same time, the changes in its electrical resistance were measured. The results showed that the properties of the self-sensing composites were significantly affected by impact energy. The damage after impact causes an increase in the electrical resistance of the MWCNTs-GF nanocomposite and increases with increased impact energy. In addition, the samples containing a high concentration of MWCNTs showed lower damage sensitivity under all impact energies levels as compared with the samples contain a lower MWCNTs concentration. Therefore, the results presented in this work have shown that it is possible to associate the change in electrical resistance of the MWCNTs-GF nanocomposite with the degree of damages caused by impact load.