bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular Prediction for the common causative agents of infectious conjunctivitis among AL-Najaf AL-Ashraf governorate patients in spring and summer.
Authors: Mohammed Ali Nazar Shammari Ahmed , Neamah Giyathaldeen , Mohammed Abdul Hussein AlShami Zina
Published: August 2023

Aim of the study: is to predict the most common causative agents of infectious conjunctivitis among AL-Najaf  AL-Ashraf  governorate during spring and summer seasons.Methods : Multiplex PCR was used to amplify viral and bacterial genes related to pathogens suspected of causing infectious conjunctivitis, the samples were collected from patients using cotton eye swabs.Results:  A total of 36 (10.29%) patients were chosen from 350 patients who attended private ophthalmic clinic in AL-Najaf AL-Ashraf governorate during spring and summer seasons. Two Cotton swabs were taken from each patient and kept frozen until the day of DNA extraction. Multiplex PCR was used to amplify genes specific for Adenovirus, Herpes Simplex Virus-1 and Herpes Simplex Virus-2, Cytomegalovirus, Varicella Zoster Virus and Chlamydia trachomitis plasmid. The multiplex PCR results found that only ten (27.77%) samples were positive for mixed infection of Adenovirus (140bp), HSV-1and HSV DNA polymerase (208, 211 bp) and only one (2.77%) sample was positive for HSV-1mixed with HSV DNA polymerase .
A comparative study between propofol vs. thiopentone plus Lidocaine effects on hemodynamic changes during laryngeal mask airway (LMA) insertion in urological surgery in Baghdad hospital.
Authors: Tariq Ali Zina
Published: August 2023

During the induction of general anesthesia, the stability of hemodynamic parameters is very important. In an idealy, all patients would be care by their anesthetists adequately to reduce all risks without interfering with the soft running of the operating list. The hemodynamic instability throughout anesthesia can be decrease by using numerous pharmacological agents and combinations have been prepared for that. Thiopentone and Propofol are intravenous anesthetics having comparatively diverse hemodynamic influences and adverse effects. Appropriate maintenance of airways securing during surgical operations is considered as the basic fundamental responsibility of an anesthesiologist. By using the modern laryngeal mask airway (LMA) with sufficient muscle relaxation, appropriate anesthetic depth and airways reflexes depression, the common problems of airway management as well as the complications after LMA insertion procedure are preventing. Our study aimed to assess the comparison effects of two anesthetic induction agents (propofol vs. thiopental- lidocaine admixture on the hemodynamic changes (heart rate (H.R), respiratory rate (R.R), oxygen saturation (SpO2), Blood pressure systolic (S.B.P) and diastolic (D.B.P) during LMA insertion for four (4) different time intervals (pre induction, at induction, at LMA insertion as well as after 5 min after LMA insertion). The current study was enrolled in Baghdad educational  hospital includes one hundred fifty (150) patients who were divided into equally groups, (115 male and35 female)75 for each group, aged (20-60) years, all patients were submit to ASA (I, II), physical grade planned for elective surgical operations under general anesthesia(G.A). All the patients were evaluated clinically, assessed and investigated prior to surgery. The allergic history or adverse reactions of barbiturate or propofol were excluded. Patients were divided into: Group (A) is receiving 2.5mg/kg (I .V) of propofol as an induction agent (n=75), and Group (B) is receiving 5mg/kg (I.V) thiopentone plus lidocaine2mg as an induction agent also (n=75). The induction induces by either propofol or thiopentone as induction agent.
Assessment of Factors that Contribute Cancer of the Larynx in Baghdad Teaching Hospitals
Authors: Hadi Atiyah Hussein
Published: August 2023

Objective: - The study aimed to assess factors that contribute to cancer of the larynx and to identify the relationship between the variables of the study with cancer of the larynx. Methodology: - A descriptive study to assess of factors that contributes cancer of the larynx.  The study was carried out in Specialized Surgical Teaching Hospital, Ibin-Al Beetar Hospital and Ibin Al Nafees Hospital for the period from January 2017to February 2018. A purposive (Non- probability) sample of (70) patients with larynx cancer was selected for the study. An assessment form was employed for purpose of the study. Test-Retest reliability was employed through computation of Pearson Correlation Coefficient (r=0.84). Content validity of the assessment was determined through a (10) panel of experts. Data were collected through the interview technique. Data were analyzed through descriptive statistical approach (frequency and percentage) and inferential statistical approach (Chi-Square).
Bioactivity of Bacteria Bacillus subtilis and Pseudomonas fluorescens against Rhizoctonia solani and Fusarium solani, which causes seed rot, seedling on cucumber in greenhouses
Authors: A.Al-Fathedhal Fadhal , A.Al-Khafaji Duaa
Published: August 2023

The research contracts with the study of the antagonistic effect of microbe against cucumber disease caused by Rhizoctonia solani and Fusarium solani. --Bacillus subtilis and Pseudomonas fluorescens were isolated from cucumber field soil. Some of the fungi diagnosing that cause the death of cucumber seeds in the greenhouse in Najaf Governorate. The results showed identification of R. solani and F. solani was carried out using the PCR technique,with forefronts and back-fronts  primers in a  range of about 600 pairs to a  nitrogen base (Base paris,bp). The analysis showed a new isolation of Rhizoctonia solani in the world according to NCBI. The bacteria isolated from the greenhousein some areas of Najaf Governorate.Results showed that Bacillus subtilis and Pseudomonas fluorescens were used as antifungal agents. Both of them have high resistance against R. solani and F. solani.  Both bacteria P. fluorescens and B. subtilis have inhibited the growth of pathogenic fungus by 71.41% especially dilution 1-10..the concentration 20, 25% of bacteria B. subtilis showed 100% inhibiting the growth of R.solani. As well as the concentration 25% of P. fluorescens showed 100% inhibiting the growth of F. solani.
Study of the relationship between the level of angiotensinogen hormone and other vital variables with stage of nephropathy in type II diabetic patients
Authors: A. Mohammad Eman , Mahmood Jwad Saher
Published: August 2023

Diabetes mellitus is the most common worldwide disease and one of its important complications is diabetic nephropathy. The activation of renin- angiotensin - aldosterone system (RAAS) is an important mediator of diabetic nephropathy. Urinary angiotensinogen, a novel biomarker of the intrarenal RAAS, is associated with the development of kidney damage. Therefore, the current study investigated the determinants of urinary angiotensinogen and its associations with staging of diabetic nephropathy and the early detection on some changes in kidney functions as result of diabetic disorder.
Asthma knowledge in a sample of students at college of Health and Medical Technologies in Baghdad
Authors: Dhiaa Ahmed Saba
Published: August 2023

Background: Bronchial Asthma (BA) is a chronic inflammatory, disease of the airway characterized. by therecurrent attacks, of the shortness, of breath that associated with wheezing, recurrent cough as well as chest tightness ,may be get worse, during exposure to smoke, dust, change in weather.  The prevalence, of a,sthmawas .increasing globally, so the natural history of asthma is still,not well defined it thought to be of genetic and environmental factors represented by exposure to allergens. Aim: To determine the level of knowledge about asthma among students in College of health and medical technologies. Methodology: one hundred forty college students were selected using a designed questionnaire for collect information of students about,the,epidemiology of asthma, symptoms, trigger factors and source of their information. The knowledge, score was estimated the,measure level of the ,students’ knowledge.Results,: More than half of the sample had moderate knowledge level.
A Comparison between the Acute Effects of Coxis on renal function with that of diclofenac Sodium in patients with rheumatological disorders
Authors: Abdullah Sayer Alkafaj Kalaf
Published: August 2023

The aim of this study was identify the effect of (coxibs) on renal function in comparison to the traditional (NSAIDs) to provide more insight on this issue. Particular emphasis has been paid to the possible acute renal toxicities such as acute decline in renal function, hyperkalaemia, hypertension and sodium and water retension, the study was conducted during the period from (February –August) 2018 , Rheumatological out-patient clinic in Ibn-Sina Teaching Hospital in Mosul. patients and methods : Eighty patients with different rheumatological disorders who have no history of pre-existing renal disease.
Determination of the Role of T-Helper 17 and 22 vs T-reg Cells in Patients with Molluscum Contagiosum
Authors: M.F. Alkhozai Ziad
Published: August 2023

Molluscum contagiosum is skin disease and well known by dermatologists, the causative agent is a pox virus. Infection, usually self-limited within few months in individuals with a normal health and immune system. From 205 case females recorded 95(46.3%) and 110(53.7%) males. The results showed that there were a highly significant increment in concentration of IL-17A (132.66 ± 24.7pg/ml) compared with control group which was (42.59±13.4pg/ml). Results also showed that there is highly significant increment in concentrations of IL-23P19 (112.33 ±17pg/ml) compared with control group which was (21.11±9.6pg/ml). Also documented data declared a highly significant increment in concentrations of IL-22 (77.11±8.8pg/ml) in comparison to control group which was (18.11±12pg/ml). The relative expression of the gene FoxP3 gene showed increment in patients group (17.723 ± 1.227) compared with control group which was (2.133±1.234), results of NFAT gene showed increment in patients group (13.676±2.223) compared with control group which was (2.743±1.133) and result of AP1gene showed increment in patients group (3.7883±1.234) compared with control group which was (1.8766±0.889). These findings indicate the potent immune response against the virus infection which belongs to Th-17 and 22 and the controlling mechanisms through the regulatory T-cells which maintain the response in the normal levels.
The association of Human Herpes virus simplex 1 and 2 infection of male genital tract and male infertility
Authors: Sahib Abdulamir Ahmed , Mahdi hassen Salah
Published: August 2023

Objectives: To investigate the association of viral infections present in the lower genital tract of males and relationship among male infertility.Methods: ELISA and RT-PCR technique of 100 semen and serum specimens, collected over 8 months from males investigated for infertility, were retrospectively assessed, by screening anti-human Herpes Simplex Virus (HSV) IgM and IgG in the serum and detection of HSV DNA in seminal fluid.
EFFECT OF INDUSTRIAL ACID RAIN ON THE BIOCHEMICAL PROPERTIES OF SOME COMMON PLANTS IN TIKRIT
Authors: Fakhre Khther AL- Shammari Ammar , Shukri Drar Al-Alosi Nasr
Published: August 2023

This study was conducted in Tikrit to compared between the plants used in decorating the sides of roads and public parks according to their ability to withstand the conditions of industrial acid rain in order to recommend them in afforestation industrial parks and areas of traffic density. Where different concentrations of industrial acidic rain were used (pH2, pH4, Ph6 and pH7.2) as well as five common plant species used for landscaping and road sides aspects (Calistemon viminalis  ,Nerium oleander, Olea europaea L , Myrtus communis , Dodonaea viscosa Linn).
PREVALENCE OF VIOLENCE AMONG A SAMPLE OF ADOLESCENTS ATTIANDING PRIMARY HEALTH CARE CENTERES IN AL-HILLA CITY
Authors: Abdulhassan Mohsen Ahmed , Fadhil Abbas Muna
Published: August 2023

Background: adolescents represent substantial majority in all societies around the world, adolescence is the period which is witnessing a lot of changes on the physical, emotional and social level. To understand how these changes affect  on the adolescents and identify health problems and behaviors that lead to these problems in the future and helps to develop a new generation free from physical, psychological and social diseases, by finding the best ways to reduce and deal with them .
Effect of Mentha piperita mint water extracts in inhibiting the growth of some pathogenic fungi
Authors: H. Mutlaq Nahid , SH. Neam Safaa , H. Hadi Wurood , I. Ali Ebtisam
Published: August 2023

The aim of the study was to study the effect of the mineral extract of Munthapiperita in the growth of fungus Rhizoctoniasolani, Aspergillusniger, Aspergillusterreus , Fusariumoxysporum, Fusariumoxysporumf. sp. (100%)  , 25%, 50%, 75% and 100%. The results showed the efficacy of the mint extract of the mint plant in inhibiting the growth of fungi and was the highest inhibition when using 100% concentration. Especially after 3,2.1 days of growth. We did not notice that solaniRhizoctonia was affected by the extract, especially after the incubation period of 7,6,5,4 days.
Seroprevalence of Rhinovirus in Common Cold Patients in Relation with ICAM-1 Level in Tikrit City
Authors: A. Hamada Thekra , Ali Arif Israa
Published: August 2023

Human rhinoviruses is the major cause of cold illness, also this virus related with more severe illness like exacerbation of asthma, chronic obstructive pulmonary disease and  the most causative agents of upper  respiratory tract complications. The study aims to evaluate the relation of ICAM-1 levels in HRV infection among common cold patients. Across sectional study was carried out in Salahaldin governorate from December, 2017 to March 2018. The number of patients were 70 patients who clinically infected with common cold and  were 17-66 years old that belonged different geographical area of Salahaldin governorate. The control group were 20 healthy individuals who matching the patients and apparently haven’t any diseases. Sera from patients and control  were obtained for estimation of  anti-HRV IgA and ICAM-1 by ALISA technique.   The study showed that 18.05% of patients enrolled in the study were positive to anti-rhinovirus IgA antibodies while no one of the control group have positive results, the relation was statistically significant. The study demonstrated that the highest mean of  ICAM-1 level was found in common cold patients who were positive to rhinovirus IgA by ELISA (786.91 pg/ml) comparing with patients with negative results and the control group with highly significant relation of ICAM-1 level with anti-rhinovirus IgA antibodies. No difference was found in rhinovirus infection in common cold patients regarding sex when 18.52 % of males and 18.6% of females were positive for anti-rhinovirus IgA antibodies. The study showed that there was no significant relation of rhinovirus infection and age of common cold patient enrolled in the study and the high rate of infections was occurred among the age group 37-46 years and the lowest rate (15%) was among the age group 17-26 years. It was concluded that there was a significant relation of ICAM-1 level with HRV infection in common cold patients
The significance of serum anti- rituximab (anti-CD20 monoclonal antibody) antibodies in treatment response of patients with B- cells malignancy
Authors: Sardar Al-Noori Aleen , Ali Mohammed Zaki , Mohammed Salih Ahmed , Sardar Zuhdi Soleen , A. Njeeb Hishyar
Published: August 2023

Background: The chimeric anti-CD20 monoclonal antibody, rituximab, is an effective therapeutic agent used for treating patients with B- cell disorders, however there is a significant variation in therapy response among patients and relapse is common. Furthermore, it is unclear why a class of patients is initially not responding and other responding become refractory and later resistant to further treatment.Aim: To study the significance of serum anti- rituximab antibodies in the patients initially responding to the treatment and became refractory and resistant to the treatment.
The Effect of Gibberellin and Salicylic on Some Indicators of Wheat (Triticum estivum L and Barley (Hordeum vulgare L) Growth
Authors: F. J. Zwein Taghreed
Published: August 2023

This experiment occurs in girls of Education collage Kufa university to know Different concentrations of Gibrillinacid (40, 60, 80) mg/L and Salsalicن mg lbrillin acid oncentraction f Education collage  acid concentrations(10,20,30)mg/L in some growth indicates  for each(Triticumaestivum L and Hordeumd vulgare L)this experiment  include culturing seeds of Triticumaestivum and Hordeumdistichu in plastic pot after Treatment with each of Gibrillinic acid and salsalic acid according to concentration mention above The results appeared that using Gibrillin acid and salsalic acid in concentrations(80 mg/ L) and (30 mg/L) respectively causing to increase significantly in stem Length and Leaf area and Leaves  content of total chlorophyl
Effect of organic, chemical solutions and solid media on the growth and yield of sweet peppers under the conditions of hydroponics
Authors: F. Hassan Waleed
Published: August 2023

An experiment was carried out for aquaculture in 2016 at the site of Zafaraniya / Research and Studies / Horticulture Department. The study included two nutrition groups, which included four nutrition medias, without a media symbol of M1, charcoal symbol of M2,     sand washed symbol M3 and  mixture of charcoal and sand symbol is M4. the second factor is the nutritional solutions and the first chemical solution, which is symbolized by S1, the second solution S2, which ensures the addition of the humic acid at a rate of 10 ml L-1 the third solution is the addition of the humic acid at a rate of 10 ml L-1 with the first nutrient solution and its symbol S3. to study the effect of organic and chemical solutions and the solid media in the growth and yield of pepper class under the conditions of aquaculture to identify the best media and a solution for the cultivation of sweet peppers under the hydroponics system. the results showed a significant increase in plant height and leaf area and the content of chlorophyll in the media of charcoal M2 with the mixture of chemical and organic nutritional solutions S3 there is a significant decrease in the dry weight ratio of the vegetative group to the dry weight of the root mass in the middle of the M2 charcoal and the mixture of chemical and organic  nutritional solutions S3. There was a significant increase in plant yield, total yield, and fruit content of ascorbic acid and beta-carotene in the middle of M2 and the mixture of chemical and organic nutrients. the treatment of the interference recorded the highest M2S3 values of 36.00 cm, 36.53 cm2 and 396.0 mg100gm-1 wet weight per plant height, leaf area and chlorophyll. the M2S2 treatment recorded a low value of the dry weight ratio of the vegetative to the dry weight of the root mass which was 0.64 recorded the same treatment M2S3 highest values of 1.30 kg-1 and 19.77 tons ha-1 and 133.0 mg 100-1 ml juice and 1.57 mg 100-1 ml juice for each plant and the total and ascorbic acid and beta-carotene Respectively.
Study of Excess Molar Volumes of the Binary Mixture of 1-Hexanol and Benzene at 303.15 K Temperature
Authors: Dwivedi Sonu
Published: August 2023

The densities, ρ of pure 1-Hexanol, Benzene and their binary mixture covering the whole composition range have been measured at 303.15 K temperature. Excess molar volumes VmE, partial molar volumes, Vi have been calculated from the ρ data. To obtain correlation coefficients and standard deviations VmE was fitted to Redlich–Kister type function in terms of mole fraction. In the whole range of composition the values of VmE were found to be positive. The positive values of VmE were shown due to depolymerization of the network structures and disrupt their H-bonding and resulting into volume expansion.
Evaluation of Causes of Post-Menopausal Bleeding: A Hospital-Based Study
Authors: Naher Shamsun , Shuchi Ferdous Ara , Shompi Sufia Begum , Areen Samira
Published: August 2023

Midline cerebral congenital malformations, despite their relative rarity in the general population, with their high rate of Introduction: Postmenopausal bleeding is frequent in gynecology and occurs approximately in 5% to 10% of postmenopausal women. But most of the causes of post-menopausal bleeding are benign and treated conservatively. Women with postmenopausal bleeding have a primary or secondary malignancy of about 10%. So before starting treatment malignancy must be excluded. Common malignancies among them are endometrial or cervical carcinoma and rarely, ovarian cancer. The incidence of malignancy in the postmenopausal period remains sufficiently high, so it requires immediate investigations for early diagnosis, prompt treatment, and vigilant follow-up. The objective of the study is to evaluate the causes of postmenopausal bleeding in tertiary care hospitals in Dhaka city. Methods: This retrospective study was conducted at the Department of Obstetrics and Gynecology in Delta Medical College and Hospital, Dhaka, Bangladesh. The study duration spanned 12 months from July 2022 to June 2023. The study population consisted of 72 patients who presented with postmenopausal bleeding. The sampling for this study was conducted using a consecutive sampling method. Ethical approval was obtained from the ethical review committee of the study hospital. Descriptive statistics were used to summarize the demographic and clinical characteristics of the study participants. For the statistical analysis, the Statistical Package for the Social Sciences (SPSS). Results: Among 72 cases of postmenopausal bleeding, we found 9 cases of cancer (12.50%). Among them, 2 cases were cancer of the uterine cervix and 7 cases were cancer of the uterine corpus. Benign pathology was more frequent (63 cases: 87.50%), essentially presented atrophic endometritis 15 cases(20.83%), endometrial hyperplasia without atypia27.78% cases, endometrial polyp 16.67% cases, endocervical polyp 5.56% cases, cervical polyp 8.33%, leiomyoma found in 5.53% cases and preinvasive disease about 2.78% cases. Histopathological findings in 2 cases of carcinoma cervix were invasive squamous cell carcinoma and 7cases of endometrial cancer were endometrial adenocarcinoma. Cancer increased with advanced age while the incidence of bleeding decreased with age. Within 45 to 65 years of age is more frequent to develop post-menopausal bleeding. Conclusion: Even though causes of post-menopausal bleeding are mostly benign and treated conservatively but malignancy must be ruled out by endometrial and cervical biopsy.
Influence of Service Quality, Price Perception and Quality of the Customer Experience Customer Loyalty with Customer Satisfaction as a Variable Intervening
Authors: Marwa Rosyidah , Astini Rina
Published: August 2023

The impact Covid-19 epidemic made all operations have gone digital in response to the Next Normal. Increasing competition in the information and communication industry demonstrates the progress of digital transformation for the telecommunication requirements of not only individuals, but also businesses as the primary target market form of company. To maintain the longevity of the company's operation, steps must be taken to understand the demands of customer satisfaction. This study aims to analyze Service Quality, Price Perceptions and Customer Experience on Customer Loyalty of Telkom Indonesia's Enterprise Company with Consumer Satisfaction as an Intervening Variable. According to internal business data for 2022, the research population is 150 enterprise customers with SEM-PLS as analysis method. The results showed that service quality, price perception and customer experience had a significant positive effect on enterprise customer satisfaction and customer satisfaction had a significant positive effect on customer loyalty. Customer satisfaction has a significant positive effect on Service Quality and Price Perception on customer loyalty, while Customer Experience has an insignificant positive effect on customer loyalty.
Hyperadrenocorticism in Dogs: Impact on Reproduction and Diagnostic Insights from Ultrasonography
Authors: Rasool Akhter , Sarath T. , Ali M. G Mohamed , Sureshkumar R. , Krishnakumar K.
Published: August 2023

Canine Cushing's syndrome, also known as hyperadrenocorticism (HAC), is one of the most prevalent endocrinopathies observed in dogs, characterized by elevated cortisol levels. The majority of cases are associated with pituitary tumors, leading to excessive production of corticotrophin (ACTH), thereby stimulating the adrenal glands to secrete cortisol. Clinical manifestations arise from the rise in cortisol concentration and encompass diabetes mellitus, polyuria, and polydipsia. Additionally, prolonged administration of glucocorticoids (iatrogenic) can also contribute to the development of Cushing's syndrome. The surplus cortisol resulting from this condition not only impacts the affected dog's health but also exerts adverse effects on various endocrine systems, leading to anestrus, infertility, premature labor, and high fetal mortality in canines. Therefore, a comprehensive understanding of these reproductive implications is essential to manage this syndrome effectively. The diagnosis of canine hyperadrenocorticism can be done by patient history, clinical signs, specific endocrine tests, and ultrasonography. Despite its significance, knowledge regarding the reproductive implications associated with Cushing's syndrome remains limited. Hence, this review aims to provide a thorough examination of the changes and challenges related to hyperadrenocorticism in canines, with a particular focus on its impact on the reproductive system. By shedding light on this aspect, the review intends to contribute valuable insights to the existing scientific literature and promote better management of this complex syndrome in dogs.
Of Wine and Steak: Reading Gustatory Signs/Signifiers in Roland Barthes’ Essays
Authors: George Kevin
Published: August 2023

Roland Barthes’ Mythologies perhaps has the singular distinction of having baffled scholars of semiotics/cultural studies or anyone who has taken an interest in the history of French colonialism and its nefarious influence on the ‘empire’ (Algeria, in particular). This article despite its limitations, intends to demystify/unravel some ostensibly innocuous ‘culinary predilections’ in vogue (during the 1950s-1960s and in some cases even germane to the 21st century) in France. In addition to his magnum opus, I will focus on his other significant text on the same topic (and gastro nationalism), Toward a Psychosociology of contemporary food consumption.
Duodenal Adenocarcinoma: 4 Cases Report
Authors: Traore Moustapha , Sabar Jihane , Medarheri Jalil
Published: August 2023

Duodenal adenocarcinoma being the most common tumor of the small intestine: 33 to 48%, it remains very rare representing only 0.5% of malignant tumors of the digestive tract. Our retrospective study focused on four cases during the period 2017-2022 with an average age of 53.25 years and a sex ratio of 1M/3F. The clinical signs were varied with a predominance of cholestatic jaundice and a deterioration in general condition. The diagnosis was confirmed thanks to the endoscopy and the anatomopathological study of the biopsies carried out in all our patients. All our patients benefited from a surgical treatment, curative or palliative, which consisted of three cephalic pancreaticoduodenectomy and in one case a gastro-jejunal anastomosis. The post-operative follow-up was simple in two patients, one of our patients presented with gastroparesis which progressed well under medical treatment. In addition, we deplore a death which presented a hemoperitoneum related to a hemostasis disorder.
Tolosa-Hunt Syndrome: A Case Report
Authors: Almokdad Maan Ali , ALakkad Ashraf
Published: August 2023

Background: Idiopathic Orbital Inflammatory Syndrome (OIS) ranks as the third most prevalent orbital disease, following thyroid eye disease and orbital lymphoma. In cases of localized inflammation, various structures within the orbit can be affected. This includes the Extraocular Muscles (orbital myositis), lacrimal gland (dacryoadenitis), sclera (scleritis), uvea (uveitis), as well as the superior orbital fissure and cavernous sinus (Tolosa-Hunt syndrome). Case Presentation: In this report, we discuss the case of a 35-year-old man who went to the Emergency Department due to intense, throbbing pain in his eye orbit and half of his head on the right side. He had been experiencing this pain for two days. The pain was aggravated by eye movement and accompanied by ipsilateral redness, mild photophobia, and blurred vision. The patient had no significant medical history prior to this episode. Upon eye evaluation, findings included mild swelling of the right eyelids, painful eye movements, inferior corneal erosions, and conjunctival chemosis with superficial and deep vessel congestion. Visual acuity was reduced due to myopic refractive error. Magnetic Resonance Imaging (MRI) revealed a soft tissue lesion in the right orbital apex extending into the right cavernous sinus, suggesting an inflammatory etiology such as Tolosa-Hunt syndrome. To investigate further, the patient underwent various diagnostic tests, including laboratory investigations, chest X-rays, and serological tests. These tests revealed unremarkable findings, ruling out systemic pathology. The patient received intravenous Solumedrol (Methylprednisolone) followed by oral Prednisolone, resulting in a dramatic improvement in symptoms. Conclusion: This case highlights the importance of a comprehensive diagnostic approach in evaluating severe orbital and hemi cranial pain. Prompt initiation of corticosteroid therapy can lead to rapid symptom resolution and favorable outcomes in patients with Tolosa-Hunt syndrome.
Rare and Unusual Cause of Adults Epistaxis
Authors: Belhaj N. , Bencheikh R. , Benbouzid M. A. , Essakalli L.
Published: August 2023

Mature teratomas, or teratoid tumors, or benign teratomas, of the nasal cavity and sinuses are exceptional the diagnosis is histopathological and shows within the lesion different types of tissue: fat, glial, muscular, cartilaginous, bone and respiratory. Teratomas are rare congenital neoplasms that originate from pluripotent cells. In this article, we report the first case of a nasal teratoma. We also discuss methods for diagnosing and treating upper respiratory teratomas, and include a brief literature review.
Assessment of Antifungal Properties of the Exudate Gel from the Stem of Caralluma retrospiciens Against Clinical Isolate of Candida albicans
Authors: Moni Sivakumar S. , Menachery Santhosh Joseph , Elmobark Mohamed Eltaib , Alam Mohammad Firoz , Gohal Gassem , Abdelsalam Karim , Taymour Soha , Basode Vinod Kumar , Banji David
Published: August 2023

The desert plant C. retrospiciens (Ehrenb.) is an inhabitant of the southern region of Kingdom of Saudi Arabia (KSA). The stem of C. retrospiciens produces a gel which is often applied by local people to cure wounds. This study was aimed at determination of the antifungal effect of the exudate gel (EG) against Candida albicans (C. albicans). The antifungal activity of EG was measured using agar well diffusion method. Results showed excellent antifungal activity of the exudate gel. The spectrum of antifungal activity of EG against C. albicans was almost equivalent to that of standard amphotericin B, with statistical insignificance (p < 0.05).
“Health Benefits of Beetroot Juice” - A Review
Authors: V Sukanya , S Neetha Dalvi , Renukadevi DN
Published: August 2023

A major problem for adolescent girls is malnutrition and anaemia. Inadequate nutrition during adolescence has the potential to have a serious negative influence on the reproductive years and beyond. The likelihood that Indian girls would acquire anaemia is doubled since they typically marry and have children before their growth spurt is complete (Chatterjee, 2008). Because of its high nitrate concentration and beta carotene content (19690 mcg/100g), beetroot juice with jaggery aids in the mobilisation of stored iron and increases haemoglobin levels in anaemic people. With its potential to stabilise blood pressure, beetroot juice is used to treat anxiety. In persons with diabetes, it is believed to improve blood flow, lower blood pressure, and improve athletic performance. Because beetroot juice has a diuretic effect and is occasionally combined with Amla juice, eating beets is recommended in cases of gonorrhoea. Heart disease, diabetes, and obesity are all decreased by beetroot juice. Jaggery's high iron and folate content assists adolescent girls with a number of menstruation issues, including easing stomach pain during periods and preventing anaemia by maintaining a proper volume of blood cells. Increased blood counts, better circulation, and a rise in the capacity of erythrocytes to carry oxygen are all results of beetroot juice's assistance in the absorption of iron.
Nurses’ Generational Differences Related to the Workplace and Leadership
Authors: Alzuman Abdulrahman Saad , Alzouman Omar
Published: August 2023

Background: Nurses form a professional major group among healthcare providers. Within recent years, providing a system of healthcare delivery that is of high-quality has been a considerable challenge. To reach that level of quality, an efficient level of job satisfaction among the nurses must be fulfilled. Aim: The purpose of this study was to compare nurses at King Faisal Specialist Hospital and Research Centre in terms of gender, age, and level of education in order to determine how these factors influenced the nurses' views of the workplace-related dimensions, nursing productivity, and the leadership practices of their managers. Methods: It was a cross-sectional study. Between July 1, 2022 and February 28, 2023, researchers at King Faisal Specialist Hospital and Research Centre in Riyadh, Saudi Arabia, gathered the necessary data. Socio-demographic variables such as gender, education level, age, and employment status were gathered via a self-administered anonymous computerised questionnaire. The second section of the survey was the 28-item McCloskey/Mueller Satisfaction Scale, which was broken down into 8 categories. The SPSS 24 program was used to examine the data. Results: Of the total respondents, 82% were females mostly within the middle age category between 26-41 years old, with the majority of the participants (N=84) belonging to Generation Z and A. Furthermore, there were no significant associations detected regarding educational level. On the other hand, there was a significant association between gender and control and responsibility and a significant association between age and scheduling. Also, there was significant association between work schedule and interaction opportunities. Conclusion: This research has significance for the hospital management and nurse educators as well as managers, prompting them to reconsider their management competences in order to establish effective techniques for managing a multigenerational workforce.
Evaluation of the use of Traditional and Conventional Oral Hygiene and Disease Preventive Methods in the City of Douala, Cameroon
Authors: Loé Gisèle Marie-Marguerite Etamé , Obed Vegah Gwe , Belinga Lawrence Essama Eno , Ludwine Ngah , Caroline Ngo Nyobe , Ngene Jean-Pierre , Sone Bertin
Published: August 2023

Introduction: Oral diseases being a preventable oral condition and a non-communicable disease could be of little concern but about 3 billion people suffer from these conditions worldwide. This study seeks to evaluate the means and methods of oral hygiene and disease prevention in the city of Douala by adults. The population of Douala is chosen due to the fact Douala is a metropolitan city and most representative of the Cameroonian population in which similar studies have not been carried out. Methodology: A cross-sectional questionnaire study was carried out with random sampling of 498 participants. Data was collected using a questionnaire based on the objectives which included identifying the means and methods used, the behaviors of the population in relation to oral disease prevention, the reasons for the behaviors and the methods and used as well as determining their satisfaction in oral disease prevention using the latter means, methods and behaviors. The data inputted, organized and analyzed using Microsoft excel 2016 and SPSS version 26. In addition to percentages, chi square and regression analyses were carried out and represented for various variables in the questionnaire. Results: It was found out that the population of Douala generally had an above average satisfaction in oral disease prevention due to the use of more conventional means and methods like toothbrushes (94.78%) and bicarbonate mouthwash (27.4%) while the main traditional substance was the neem extract (18.75%), and green tea extracts (16.67%). Their main reasons for using these methods were effectiveness (38.55%), low cost (20.88) and availability (20.08%) with a significant relationship between traditional methods and low cost. Majority of the population used both conventional and traditional methods (55.16%). The studied population show better oral hygiene and disease prevention with a higher level of education and greater monthly allowance. Conclusion: After this evaluation, proper oral healthcare in disease prevention produces satisfaction with oral hygiene at least twice a day with toothbrush and bicarbonate mouthwash, carrying out routine dental visits, participating in sensitization which are directly related to education and finances. In the same light, traditional methods include chew stick, extracts like green tea and neem.
Comparative Evaluation of Marginal Microleakage of a Bioactive Composite Resin Using Three Different Bonding Agents in Non-Carious Cervical Lesions– An In Vitro Study
Authors: Jambagi Shweta R , Totad Shrishail , R Srinidhi S , Saraf Prahlad , Patil Basanagouda
Published: August 2023

Background and objectives: Increasing prevalence of non-carious cervical lesions makes it imperative to overcome challenges in tooth preparation, isolation and restoration. Bio-active restorative materials are relatively new concepts in dentistry having the potential to prevent secondary caries, a major cause of failure of restorations. Composite resins have the disadvantage of polymerization shrinkage leading to marginal gap formation. This study evaluated the marginal microleakage properties of Activa bio-active composite resin using three different adhesives in non- carious cervical lesions. Materials and method: Forty extracted maxillary & mandibular premolars for the study were collected. The specimens were divided into groups (n= 10). Box type class V cavities, 2mm inciso-gingivally, 3mm mesio-distally & 2mm in depth was prepared on the buccal surfaces. Group 1: Activa bio-active resin +No bonding agent, Group 2: Activa bio-active resin +Tetric N-bond, Group 3: Activa bio-active resin +Single bond Universal, Group 4: Activa bio-active resin + G Premio bond. Restorations were done and samples subjected to thermocycling. They were immersed in Rhodamine B dye solution for 24 hours. The samples were longitudinally sectioned in a bucco-lingual direction with diamond discs, examined under a stereo-microscope with 30x magnification and depth of penetration analyzed. The statistical analysis for microleakage was performed using the Kruskal Wallis test followed by the Mann Whitney U-tests with the Wilcoxon correction for pair-wise comparisons at a significance level of p < 0.05. Results: Activa bio-active resin + G Premio bond showed lesser micro-leakage compared to other groups and the difference was statistically significant. Conclusion: Activa bioactive resin with G Premio bond, 8th generation bonding agent showed lesser micro-leakage when compared with 5th and 7th generation bonding agents.
Analysis of Histological Prognostic Factors in Colorectal Carcinoma and Relationship of VEGF and E-Cadherin Expression in Prognostic Assessment
Authors: Femy Aysha , Rao Anuradha Calicut Kini , P Supriya
Published: August 2023

Colorectal carcinomas (CRC) are associated with several histopathological and molecular factors of prognostic and hence therapeutic implications, including for epithelial mesenchymal transition (EMT) and angiogenesis. Downregulation of E-cadherin is a crucial step in EMT, directly related to tumor progression, invasion, and metastasis. Vascular endothelial growth factor (VEGF) induces angiogenesis and thereby tumour progression and metastases. Our objective was to analyse VEGF and E-cadherin expression in patients with CRC and to effectively assess the relationship of these with histopathological factors. 50 cases of CRC obtained over eighteen months duration, were included in the study. Haematoxylin and Eosin-stained sections were studied for histopathological factors. Immunohistochemistry with E-Cadherin and VEGF were performed on representative sections and evaluated. Histopathological features of importance noted were low grade tumour budding (55.5%), Infiltrative invasive front (83%), lympho-vascular invasion (50%). Preserved expression of E-Cadherin was seen in 66% of the cases, and 34% reduced expression, predominantly noted in patients above the age of 50, increased tumour size, mucinous variants, advanced TNM stage, lymph node involvement and high-grade tumour budding. VEGF staining was seen in 64% of the cases with varying intensity. Increased VEGF expression was noted in poorly differentiated tumours, advanced Duke’s stage and with lymph node metastasis. Colorectal carcinomas with high grade tumour budding were associated with lymph vascular invasion, infiltrative invasive front and significantly correlated with TNM stage. High grade tumours and adverse histopathological prognostic factors revealed a reduced E-cadherin expression and increased VEGF expression.
Duodenal Metastasis from Colorectal Cancer: A Case Report
Authors: Chehal Aref , Ibrahim Mariam Emadeldin , ALakkad Ashraf , salami Aisha Al , Sheikh Hassan Shahryar , Silymon Deepthi , Harthi Salem Nasser Al , Chintakuntlawar Ashish Vittalrao , Uttamchandani Ashok , Ghashir Najla Saleh Ben
Published: August 2023

Background: The occurrence of metastatic colon lesions in various organs has been documented extensively in the literature. The liver, lungs, and bones are the most frequently affected sites. Metastasis in the duodenum due to colon cancer is an infrequent occurrence. Case Presentation: We present a detailed case report of a 65-year-old female patient diagnosed with metastatic colon cancer to the duodenum. The patient initially underwent extended right hemicolectomy for stage III low-grade adenocarcinoma of the colon. Adjuvant chemotherapy was administered, resulting in a period of apparent remission. However, in 2020, the patient experienced elevated tumor marker levels, prompting further investigations. Endoscopy revealed an irregular mass infiltrating the muscle layer in the duodenum, confirming malignant involvement. The patient underwent curative distal gastric duodenectomy, with pathology results indicating a colonic origin of the tumor. The patient received first-line palliative chemotherapy with FOLFOX rechallenge and the addition of AVASTIN. Several cycles of chemotherapy were completed, with satisfactory tumor response observed in follow-up PET scans. Maintenance therapy was initiated after achieving disease-free status on CT scans. However, in October 2022, the patient exhibited increasing tumor marker levels and new findings on PET scan, leading to the initiation of second-line palliative therapy with FOLFIRI and ramucirumab. The patient has received multiple cycles of second-line therapy, with the most recent PET scan in February 2023 showing a favorable treatment response, including a decrease in the size of existing nodes and no identification of new lesions. Conclusion: In conclusion, this case exemplifies the journey of a patient with stage 3 colon cancer who initially responded well to surgery and adjuvant chemotherapy, but experienced subsequent relapse in the duodenum. Despite surgical intervention and palliative chemotherapy, the patient developed metastasis in the liver, lung, and multiple lymph nodes.
Wnt/β-catenin Signaling in Endometrioid Endometrial Cancer and Precursor Lesions
Authors: Yadav Sunita , Makker Annu , Nayak Seema , Agarwal Preeti , Singh Uma , Singh Uma Shanker , Goel Madhu Mati
Published: August 2023

Endometrioid endometrial carcinoma (EEC) is most common invasive malignancy of female genital tract. In spite of advances in diagnosis and treatment, incidence of EEC has been rising because of increasing aging population and prevalence of obesity. Therefore, there is need of research exploring the underlying molecular mechanism of EEC and its precursors. Wnt/ β-catenin signaling are involved in the progression and invasion of EEC. However, the potential role of Wnt/ β-catenin signaling and its effectors in endometrial cancer and precursor lesions remains to be investigated. In the present study a total of 95 samples of endometrial biopsies were assessed histopathologically along with β-catenin expression by immunohistochemistry and promoter methylation of adenomatous polyposis coli (APC) gene by bisulfite method. Women age ranged from 35 to 70 years whose endometrial biopsy and resected samples were obtained. Expression of β-catenin was observed in 28/39; 72% of EEC, 23/37; 62% of precancer cases and 4/19; 21% of normal proliferative endometrium. APC promoter was completely unmethylated in all controls (14/14) and precancer (10/10) groups, however, only one case (1/13, 8%) of cancer was methylated. The present study showed that expression of β-catenin was upregulated in EEC and precursor lesions suggesting involvement of Wnt/ β-catenin signaling from an early stage of development of cancer from precancer. The information might offer a potential therapeutic target for EEC and could also be used as a screening tool in endometrial hyperplasia (EH) cases for detecting potentially precancerous lesions.
Work Effectiveness Examined through the Aspects of Workload and Burnout
Authors: Retnowati Eli , Hariani Mila , Irfan Moch. , Darmawan Didit , Putra Arif Rachman , Anjanarko Tri Seno , Munir Misbachul
Published: August 2023

This study aims to examine the influence of workload and burnout on employee work effectiveness. It employs a quantitative method with data collection through questionnaires. The research methodology involves data collection through questionnaires distributed to 120 employees of PT ABC in Gresik City. The sampling technique employed is saturation sampling, involving all employees of PT ABC in Gresik City. Regression analysis is utilized to test the relationship between workload and burnout variables on employee work effectiveness. The results of this study indicate a significant relationship between workload and burnout and employee work effectiveness. The higher the workload borne by employees, the higher the likelihood of experiencing burnout, which ultimately has a negative impact on their work effectiveness
ARDUINO-BASED SOLAR WATER PUMP MOTOR CONTROL TO ADJUST WATER CIRCULATION IN HYDROPONIC PLANTS
Authors: Rochman Sagita , Krama Danu
Published: August 2023

Hydroponic plants are currently very popular because they do not require large land and land. By planting hydroponically, the harvest will be faster but it is necessary to pay attention to the air that is maintained, the purpose of distributing plant root nutrients, the use of solar power as a driving force for DC (Direct Current) water pumps in hydroponics is designed using several tools including: photovoltaic 10 Wp type polycrystalline, solar charge controller, 12v 5Ah battery, Arduino UNO, Dsi8b20 temperature sensor and 12V DC water pump. In this study, the author will make a solar pump motor drive (Solar Panel) and regulate the circulation of air volume and temperature in the hydroponic plant.