bluuebunny/crossref_metadata_2025 huggingface dataset:
Security Risks Management Strategies and Conducive Work Environment in Federal Universities South-South Nigeria
Authors: Ekumankama Chidi Okorie , Ereh Cecilia Emuji , Friday Anietie Joshua
Published: December 2024

The study determined the extent to which security risks management strategies predict conducive work environment in Federal Universities South-South Nigeria. Two specific objectives, research questions and null hypotheses were stated to guide the study. The research design of the study was the correlational research design. The population of the study consisted of 5,161 lecturers from four federal universities in South-South Nigeria. A sample size of 400 lecturers was used for this study. The sample size was determined using Taro Yamane formula. Simple random sampling was then used to select respondents for the study. The researcher developed two instruments entitled “Security Risk Management Strategies Questionnaire (SRMSQ)” and “Conducive Work Environment Questionnaire (CWEQ)” were used for data collection. The draft of the two instruments was subjected to face validation by three experts from the Faculty of Education, University of Uyo. The reliability of the instruments of the study was determined through the split half method. The instrument was administered on 50 respondents (lecturers) who were not part of the sample. The data collected was subjected to Cronbach Alpha reliability test to ascertain the reliability indices of the instruments. This gave values of 0.87 and 0.83 for SRMSQ and CWEQ respectively. Simple Linear Regression was used to answer the research questions and to test the null hypotheses at .05 level of significance. Findings of the study reveals significant influence of security risk awareness and identification on conducive work environment. The overall effect indicates that security risk management strategies have a very high positive and significant predictive effect on conducive work environment. It was recommended among others, that school authorities should create more awareness among members of staff on safety and security issues. The outsourcing of security functions to private security firms should be given to firms with capable manpower and technology as well as leverage.
Documenting the Experiences of Undocumented Learners in South African Public Schools: An Impact Study
Authors: Mashele Shonaphi F. , Mafuwane Barber Mbangwa
Published: November 2024

The status of being an undocumented learner presents a myriad of learning challenges to the affected learners. Schools in South Africa, particularly in the rural areas and those areas along the borders with Mozambique and Zimbabwe, have over a million undocumented learners who are either children of South Africans or children born from non-South African parents. The purpose of this study is to explore the experiences of the undocumented learners, their parents, and the schools against the findings of the Phakamisa judgement of 2017, Case No.2480/2017 which was held in the Eastern Cape High Court in Grahamstown. The undocumented learners are children who join the schooling system; grow up being undocumented in the system, become teenagers or young adults in the system and end up exiting the system without anything to show for the number of years they stayed in the system. This paper explores the problem faced by undocumented learners and its implications to them in the classroom and beyond. This paper will, in concert with the findings of the Phakamisa judgement, implore the policy makers to move beyond compliance and put together policies that will protect the right of children through interdepartmental cooperation to fast track the documenting of learners at birth, irrespective of the status of their parents.
Study of Genetic and Clinical Outcomes of Consanguineous Marriages
Authors: Balwan Wahied Khawar , Saba Neelam
Published: November 2024

Consanguineous marriage (CM) or cousin marriage is a type of inter-familial union, defined as the marriage between two blood-related individuals who are second cousins or closer (inbreeding coefficient ⩾ 0.0156). Marriage is one of the important vital event and entry in to reproductive life in India. Prevalence and pattern of marriage varies across the states, regions and according to their religion and caste. Consanguineous marriages have been practiced since the early existence of humans. Consanguinity is the marriage between close relatives. Though consanguineous matings have cultural and socioeconomic advantages, their offspring have an increased risk for recessive disorders. The risk is not uniform in all cases and it varies based on several factors. Consanguinity is a deeply rooted social trend among one-fifth of the world population mostly residing in the Middle East, West Asia and North Africa, as well as among emigrants from these communities now residing in North America, Europe and Australia. The mounting public awareness on prevention of congenital and genetic disorders in offspring is driving an increasing number of couples contemplating marriage and reproduction in highly consanguineous communities to seek counseling on consanguinity. The article discusses the different type of measures that can be taken by a consanguineous couple before and after marriage to avoid genetic disorders in their progeny.
Compressing Lipoma of the Guyon Canal
Authors: Benyass Youssef , Laghouagha Otman Oulad , Boukhriss Jalal , Chafry Bouchaib
Published: November 2024

Lipoma is a common benign tumor of soft tissues but rarely located in the hand or being responsible for neuropathy. A case of compressive lipoma of the Guyon canal with purely sensory disorders has been evolving for 04 years in a 56-year-old woman. The mass was removed without any damage to vascular, neural, or tendinous structures. Postoperative recovery was straightforward, and the patient regained good mobility in the hand and fingers.
In-vivo and In-vitro Screening of Anti-Diabetic Activity of Pongamia pinnata Leaves on Experimentally Induced Diabetes
Authors: R Chaitra, K. , Siddiq Abubaker , H Rudrayyaswamy, M.
Published: November 2024

Diabetes mellitus, a chronic metabolic disorder marked by hyperglycemia, affects millions worldwide. This study explores the antidiabetic potential of ethanolic extract of Pongamia pinnata leaves (EEPPL) using dexamethasone-induced diabetic rat models. EEPPL was prepared via Soxhlet extraction and tested in five groups (n=6 each): normal control (saline), positive control (dexamethasone 1 mg/kg), standard (metformin 40 mg/kg), low dose (EEPPL 250 mg/kg), and high dose (EEPPL 500 mg/kg). Treatments were administered for 10 days, with assessments on day 10 including body weight, fasting blood glucose (FBS), oral glucose tolerance test (OGTT), lipid profile, lipid peroxidation, and catalase levels. In vitro α-amylase and α-glucosidase assays were also conducted with acarbose as a reference. Results showed significant antidiabetic and antioxidant effects in dexamethasone-induced diabetic rats. The standard group had highly significant improvements in FBS and OGTT. The high-dose EEPPL group exhibited moderate to highly significant effects on FBS, OGTT, and lipid profile, with weight improvements and reductions in cholesterol levels. Antioxidant assessments revealed reduced lipid peroxidation and increased catalase activity in the high-dose group. The in vitro assays demonstrated dose-dependent inhibition of α-amylase and α-glucosidase, comparable to acarbose. In conclusion, the study suggests that EEPPL has notable antidiabetic and antioxidant properties, supporting its potential as a natural therapeutic for managing diabetes and oxidative stress.
A Rare Connection: Case Report of Neuroendocrine Tumors Misdiagnosed as Hemorrhoids
Authors: Mohamed Rawia Mubarak , ALakkad Ashraf , Panda Ipsita , Chehal Aref
Published: November 2024

Background: Hemorrhoids are a prevalent condition affecting the anal and rectal area, often resulting in symptoms such as bleeding, pain, and prolapse. While typically benign, they can coexist with other anorectal issues, including anal fissures and polyps. Rarely, neuroendocrine tumors may be discovered in patients with hemorrhoids, underscoring the necessity for thorough evaluation and histopathological examination to identify and address any significant underlying conditions. Case Presentation: This case describes a 39-year-old male presenting to the clinic on August 13, 2024. He reported a one-year history of rectal bleeding, pain, burning, and prolapse during defecation, along with occasional constipation. Physical examination revealed third-degree hemorrhoids, a chronic anal fissure, and an anal polyp. The primary diagnosis was third-degree hemorrhoids, with secondary diagnoses of chronic anal fissure, anal polyp, and constipation. The patient underwent elective surgical interventions, including stapler hemorrhoidopexy, fissurectomy, sphincterotomy, and excision of the anal polyp, all performed under general anesthesia without complications. Histopathological analysis of the excised hemorrhoidal tissue revealed a Grade 1 neuroendocrine tumor measuring 3 mm, with no evidence of malignancy elsewhere. Postoperative recovery was stable, with the patient reporting no significant complications during follow-up. Conclusion: This case illustrates the complexity of managing hemorrhoidal disease and its potential associations with other anorectal conditions, such as anal fissures and polyps. The identification of Grade 1 neuroendocrine tumors emphasizes the importance of thorough evaluation in patients presenting with rectal symptoms, even when benign conditions are suspected.
Evaluating the Success of Revision Spine Surgery in Patients with Failed Back Surgery Syndrome: A Prospective Study
Authors: Azad Dr. Abul Kalam , Rahman Dr. Md. Munzur , Beg Dr. Mirza Osman
Published: December 2024

Background: Failed Back Surgery Syndrome poses a significant challenge due to persistent pain following spinal surgery, greatly affecting patient quality of life and healthcare resources. Objective: This study aims to evaluate the effectiveness of revision spine surgery in FBSS patients, identifying key predictors for improved clinical outcomes. Method: A prospective study was conducted at a tertiary-level hospital in Bangladesh, involving 98 FBSS patients undergoing revision spine surgery from June 2020 to June 2023. Outcome measures included pain reduction (Visual Analog Scale), functional improvement (Oswestry Disability Index), and patient-reported quality of life. Result: Six months post-surgery, 74% of patients experienced clinically significant pain reduction (>50% on VAS), while 63% showed notable functional improvement with a reduction in ODI scores of over 40%. Quality of life improved for 68% of patients, with 25% reporting a complete return to daily activities. Among surgical types, decompression led to a 58% improvement in mobility, while fusion procedures resulted in a 70% pain reduction. However, 12% of patients reported little to no improvement, and 5% experienced worsened symptoms, underscoring the variability in outcomes. Predictive success factors included shorter intervals between surgeries and lower initial pain levels (p < 0.05). Overall, revision surgery was beneficial for the majority, but not all patients achieved desired outcomes. Conclusion: Revision spine surgery in FBSS patients can lead to significant improvements, though outcomes vary. Identifying predictive factors is essential to guide surgical planning and enhance patient selection.
PEMBUATAN HAND SANITIZER BERBASIS BAHAN ALAM DI DESA TATAH LAYAP, KALIMANTAN SELATAN ERA PANDEMI COVID-19
Authors: Febrianti Dwi Rizki , Niah Rakhmadhan
Published: November 2024

During the pandemic the need for hand sanitizer became the basic needs of the world community. Maintaining hygiene and health protocols are top priorities to avoid exposure to covid-19. The training on making Natural Hand Sanitizer in Tatah Layap Village, Banjar Regency is expected to increase community creativity to support the economy and community protection materials during the Covid-19 pandemic. The main materials made in this training are from natural materials that are around the village environment, Betel and Lemongrass. Through this training, people have more knowledge about business opportunities that can be created through creativity and skills so that the hand sanitizer they make can have value. The training is carried out through several stages, namely by providing materials and knowledge, in the implementation of the training, participants will be guided. Then the results can be utilized by the community for daily life and become a superior product.
PEMBERDAYAAN TANAMAN OBAT KELUARGA (TOGA) UNTUK MENGATASI HIPERTENSI DAN KOLESTEROL DI DESA GUDANG HIRANG RT 07
Authors: Melviani Melviani , Nabillah Syafira , Inayati Aisyah , Fakhriah Siti Nurintan
Published: November 2024

Family Medicinal Plants (TOGA) are plants that are very efficacious, especially in the health sector. Based on data collection on disease complaints experienced by the community in Gudang Hirang Village Rt 07, 50% stated that they had hypertension and 33% suffered from cholesterol. The purpose of this activity is to increase knowledge to the people of Gudang Hirang Village Rt 07 about the types of family medicinal plants that can be used to control hypertension and cholesterol. The cadre of TOGA planting was carried out to the community by using ginger and celery plants. Ginger plants have many benefits, especially overcoming hypertension and strengthening the human immune system. While celery can be efficacious as a cholesterol treatment because it can reduce total cholesterol levels in hypercholesterolemia. The method used is a direct training method where the target is community representatives of Gudang Hirang Village Rt 07. The results of the activity show very high enthusiasm of cadres in increasing knowledge about the treatment of hypertension and cholesterol using medicinal plants ginger and celery. Thus, it is hoped that the education provided can be applied as an alternative to overcome public health problems.
DESNUTRIÇÃO INFANTIL NO NORDESTE: ANÁLISE TEMPORAL DE 2017 A 2021
Authors: Coelho Amanda Maria e Silva , Ferreira Denise de Souza , Silva Fabyanna Nunes Diniz , Cavalcanti Giovanna de Menezes , Bomtempo Gabriel Campos , Regina Santos Dantas Correia  , Medeiros Maria Eduarda Ferraz de , Damasceno Geovana Soares , Souza Raiane Ribeiro de , Marques Christielle Silva
Published: December 2024

A desnutrição infantil é um importante problema de saúde pública que afeta diversos países do mundo decorrente de múltiplos fatores, principalmente a pobreza. Este artigo tem por objetivo analisar o perfil de crianças de 0 a 04 anos de idade com diagnóstico de desnutrição, na região Nordeste. Trata-se de um estudo epidemiológico, transversal, descritivo, de caráter quantitativo de casos notificados de desnutrição em crianças de 0 a 04 anos, na região Nordeste, baseando-se na análise de registros publicados no período de 2017 a 2021, disponíveis em base de dados do Departamento de Informática do Sistema Único de Saúde (DATASUS) através do Sistema de Informações Hospitalares do SUS (SIH/SUS) e do Sistema de Informações sobre Mortalidade (SIM). Os resultados revelam que a desnutrição infantil tem acometido mais crianças menores de 01 ano, com prevalência na cor/raça branca e parda (47,3%) do sexo feminino (53,2%). Dentro dos dados hospitalares, também foi possível constatar que o tempo de permanência, assim como as despesas hospitalares, no período de 2017 a 2021, devido à desnutrição infantil, sofreram oscilações porém no geral mostraram-se crescentes, destacando o período de 2020 onde foi contabilizada uma média de 14,1 dias de permanência com um gasto estimado em 3.846.579,65 reais (17,4%). A desnutrição infantil, por ser um dos problemas de saúde pública no mundo, especialmente na região nordeste do Brasil, requer uma atenção de qualidade na assistência com emprego de práticas de recuperação e supervisão prestadas às crianças com desnutrição.
NEUROFIBROMA PLEXIFORME MEDIASTINAL INFANTIL: UM ACHADO INCIDENTAL
Authors: Vieira Donzelli Renato , Alves Coelho Neto Murilo , Ramos dos Santos Mateus , Mathiazi Di Mateos Lívia , Favarin da Silva Emilly , Lorraine de Sousa Oliveira Evellyn , Girelli Neto Saul , Kuranishi Maria Eduarda , Gruber Colombo Mateus , José Paludo Petek Dionísio , Gonçalves Dos Santos Ody Gabriel , Porfirio da Silva Neto Francisco , Stefaniak Luciano , Maria Lima Aguiar Mundim Olga , Geraldo Coelho Júnior Luilson
Published: December 2024

Introdução: Este relato de caso aborda o neurofibroma plexiforme, um tumor benigno raro que se origina nas bainhas dos nervos periféricos e que, embora mais comum em regiões superficiais, pode ocorrer em áreas profundas como o mediastino, apresentando desafios diagnósticos e terapêuticos. Metodologia: A coleta de dados foi realizada por meio da análise detalhada do prontuário médico da paciente, com informações sobre o histórico clínico, exames de imagem e o procedimento cirúrgico, além de entrevista com os responsáveis legais. Descrição do caso: Paciente de 07 anos, diagnosticada incidentalmente com neurofibroma plexiforme mediastinal durante uma tomografia computadorizada feita para investigar sintomas gripais. O tumor estava localizado no mediastino posterior, firmemente aderido à aorta torácica, sendo removido por videotoracoscopia. Discussão: A localização do neurofibroma no mediastino é incomum e, apesar de benigno, o tumor apresenta desafios cirúrgicos devido à sua proximidade com estruturas vitais. A escolha por uma abordagem minimamente invasiva foi adequada e está em consonância com a literatura sobre o manejo de tumores mediastinais. Conclusão: O caso destaca a importância do diagnóstico precoce e do tratamento cirúrgico minimamente invasivo, além da necessidade de seguimento a longo prazo, considerando o risco de recorrência ou transformação maligna.
ПРИЧИНЫ СНИЖЕНИЯ ПРОИЗВОДИТЕЛЬНОСТИ СКВАЖИННЫХ НАСОСОВ В СИСТЕМАХ ВОДНОГО ХОЗЯЙСТВА
Authors: И.Ю. Пурусова
Published: December 2024

Описаны проблемы использования подземных вод как источника водоснабжения. Основное внимание уделено производительности скважинных насосов в системах водного хозяйства. Показана схема исследуемой действующей водоподъёмной станции первого подъёма, состоящей из линейного ряда скважин, подключённых к сборному водоводу, уложенному в одну нитку. Такая схема является наиболее распространённой в существующей практике организации водозабора из подземных источников. Представлены обобщённые значения удельных дебитов водозаборных скважин с начала их эксплуатации, марки установленных насосов, а также произошедшие изменения с момента ввода в эксплуатацию водоподъёмной станции первого подъёма. На основе фактических характеристик взаимодействующих элементов системы на действующей водоподъёмной станции первого подъёма приведены последствия понижения динамического уровня воды для скважинного насоса. Приведённые исследования показали, что допустимое понижение уровня воды в скважинах необходимо устанавливать таким, чтобы обеспечивалась стабильная работа насосного оборудования, при постоянном дебите. Даны рекомендации для предупреждения снижения дебита скважины.

The article describes the problems of using groundwater as a source of water supply. The main attention is paid to the performance of borehole pumps in water management systems. I show the scheme of the operating water lifting station of the first lift, which is being described here. It consists of a linear series of wells connected to a prefabricated water conduit laid in one line. This scheme is the most common in the existing practice of organizing water intake from underground sources. The paper presents generalized values of specific flow rates of water intake wells from the beginning of their operation, brands of installed pumps, as well as changes that have occurred since the commissioning of the first lift water station. Based on the actual characteristics of the interacting elements of the system at the operating water lifting station of the first lift, I present the consequences of lowering the dynamic water level for the borehole pump. The study has shown that the permissible lowering of the water level in wells must be set in such a way as to ensure stable operation of pumping equipment at a constant flow rate. I also recommend how to prevent a decrease in the flow rate of the well.
ГИДРАВЛИЧЕСКИЕ ОСОБЕННОСТИ, ОПРЕДЕЛЯЮЩИЕ ЭФФЕКТИВНОСТЬ РАБОТЫ ВОДОПРОВОДНЫХ СЕТЕЙ В УСЛОВИЯХ КРАЙНЕГО СЕВЕРА
Authors: В.В. Помогаева , Д.С. Голубова
Published: December 2024

Рассматриваются особенности проектирования водопроводной сети в условиях Крайнего Севера, а также современные технологии и подходы, позволяющие эффективно решать задачи водоснабжения в сложных условиях. Целью работы является выполнение гидравлического расчета водопроводной сети, определение возможности возникновения отказов. Основным методом является моделирование режима работы водопроводной сети при разных режимах ее работы, моделирование гидравлического удара в магистральной сети. Объектом исследования является кольцевая водопроводная сеть длиной 4,7 км. На примере водопроводной сети для поселка с числом жителей 4 тыс. человек, рассмотрены и смоделированы режимы работы, выявлены проблемные участки. Предложен вариант увеличения диаметров кольцевой водопроводной сети. Приведены основные параметры для гидравлического расчета и расчетные схемы водопроводной сети. Показана схема участка водопровода при моделировании гидравлического удара в магистральной сети. Определены основные параметры при совместной работе насосов и трубопроводов. Обосновано увеличение диаметров водопроводной сети, что необходимо для соблюдения режима работы в случае возникновения пожара в разных расчетных узлах.

In the article we consider the issues of designing a water supply network in the conditions of the Far North, as well as modern technologies and approaches that make it possible to effectively solve water supply problems in difficult conditions. The purpose of the work is to perform a hydraulic calculation of the water supply network, to determine the possibility of failures in the network. The main method is to simulate the mode of operation of the water supply network under different modes of operation, modeling hydraulic shock in the main network. The object of the study is a ring water supply network with a length of 4.7km. Using the example of a water supply network for a village with a population of 4 thousand people, we considered operating modes and identified problem zones. We propose to increase the diameters of the ring water supply network. We as well give the main parameters for the hydraulic calculation of the water supply network and determine the main parameters for the joint operation of pumps and pipelines. Also, we determined the main parameters for the joint operation of pumps and pipelines. Besides, we justified the increase in the diameters of the water supply network, which is necessary to comply with the operating mode in the event of a fire in different calculation units.
СОЗДАНИЕ СИСТЕМЫ КАТЕГОРИРОВАНИЯ УЧАСТКОВ ВОЗДЕЙСТВИЯ ШУМА ОТ ЖЕЛЕЗНОДОРОЖНОГО ТРАНСПОРТА В ПРАКТИКЕ ГОРОДСКОГО КАРТОГРАФИРОВАНИЯ
Authors: Е.И. Головина , Д.А. Соколов
Published: December 2024

Представлен анализ ключевых факторов, влияющих на уровень шума и вибрации от железнодорожного транспорта. Предложена система классификации участков, подверженных вибро-акустическому воздействию. Перечислены основные элементы и параметры, учитываемые в классификации: уровень воздействия (сильное, среднее, слабое), длина исследуемого участка, состояние железнодорожного полотна, расположение путей относительно селитебной зоны. Приведено описание методики проведения замеров, результаты которых могут быть использованы в качестве входных данных для создания карты шума. Предложен методологический подход к визуальному представлению уровней шума в определенном географическом местоположении с учетом специфики железнодорожного транспорта.

The article presents analysis of key factors influencing the level of noise and vibration from rail transport. We proposed a classification system for areas subject to vibration and acoustic impact. We list the main elements and parameters taken into account in the classification such as the level of impact (strong, medium, low), the length of the section under study, the condition of the railway track, the location of the tracks relative to the residential area. We describe the measurement methodology, the results of which can be used as input data for creating a noise map. We as well propose a methodological approach to the visual representation of noise levels in a given geographic location, taking into account the specifics of railway transport.
Fixed-Dose Antiplatelet Dual Combination in Patients with Coronary Artery Disease in Turkish Population: DAPT-TR
Authors: Öz Ahmet , Toprak Kenan , Aydin Ertan , Saraç İbrahim , Doğduş Mustafa , Opan Selçuk , Yenerçağ Mustafa , Tascanov Mustafa Begenc , Kümet Ömer , Karaağaç Miraç , Özmen Murat , Murat Bektaş , Kertmen Ömer , Bekler Özkan , İnci Sinan , Huyut Mustafa Ahmet , Özderya Ahmet , Er Fahri , Duran Mustafa , Ardahanlı İsa , Baş Mehmet Memduh , Güzel Tuncay , Ceyhun Gökhan , Özdemir İbrahim Halil , Özen Mehmet Burak , Gündüz Ramazan , Erdoğan Aslan , Çetin İlyas , Barış Veysel Özgür , Yayla Çağrı , Karaduman Medeni , Aşkın Lütfü , Bekar Lütfü , Tanrıverdi Okan , Özkan Eyüp , Yeşil Emrah , Çalışkan Serhat , Kuzu Zülfiye , Uğuz Berat , Böyük Ferit , Kunak Ayşegül Ülgen , Murat Selda , Asil Serkan , Kayhan Özkan , Erdoğan Emrah , Duz Ramazan , Katkat Fahrettin , Ekin Tuba , İbişoğlu Ersin , Ateş Bilge Nazar , Ayça Burak , Ergene Asım Oktay , Zoghi Mehdi
Published: December 2024

Abstract Background Dual antiplatelet therapy (DAPT) is the treatment of choice for patients with acute and chronic coronary syndromes as it reduces mortality and prevents recurrent thrombotic complications. The assessment of both ischaemic burden and bleeding risk is crucial in deciding which DAPT to choose and how long it should be continued. Objectives The aim of our study was to perform prospective clinical follow-up of patients receiving fixed-dose combination therapy (ASA 75 mg + clopidogrel 75 mg). Our study is a multicentric, cross-sectional, observational, cohort study. Methods A total of 1500 patients who were started on fixed-dose combination DAPT for acute or chronic coronary syndrome were included in the study. Primary endpoints were hospitalization for any reason, hospitalization for cardiovascular cause, acute myocardial infarction, stent thrombosis, target vessel revascularization and bleeding; the secondary endpoints were death for any reason or cardiovascular cause and stroke. The significance level adopted in the statistical analysis was 5%. Results Median age was 63 years; 78.5% of the patients were receiving DAPT treatment for acute coronary syndrome. The rates of hospitalization for cardiovascular reasons, acute myocardial infartion, stent thrombosis and target-vessel revascularization were 7.9%, 2.3%, 1.3% and 4.2%, respectively. While the rate of BARC type 1 bleeding was 3.3%, the rate of BARC type 5, 3, or 2 bleeding was 0.6%. The secondary endpoints which were death from any cause, cardiovascular death and stroke were 0.5%, 0.3% and 0.3%, respectively. Conclusion: Our study shows that fixed-dose combination therapy is effective and safe in appropriately selected patients with acute or chronic coronary syndromes.
Local and indigenous knowledge (LIK) in science learning: A systematic literature review
Authors: Latip Abdul , Hernani  , Kadarohman Asep
Published: December 2024

This research aimed to analyse the literature regarding Local and Indigenous Knowledge (LIK) in science teaching and learning. This research uses a Systematic Literature Review (SLR) to identify articles focusing on studies regarding LIK in science education. This research explores 52 articles from Scopus and Web of Science published between 2014 and 2023 from various countries. The SLR results show that the number of publications increased yearly. LIK is a recognised research topic in various countries, such as Indonesia, the United States, Canada, Australia, and African countries. The SLR results also show types of LIK consisting of daily lifestyle behaviour, system development in society, and knowledge and practice of investigation by the community. These types related to issues in science issue of climate, ecology, medicinal plants, and astronomy. These issues are studied from the perspective of indigenous knowledge, which is harmonised with modern scientific knowledge. LIK implementation strategies in science learning include community-based and place-based education learning development strategies. Implementation of different strategies is the development of a formal curriculum that accommodates LIK, such as Cross-Curriculum Cultural Priorities, Integration of medicinal plants as important content in K-12 curriculum subjects in the USA, Development of chemistry and physics practicums based on knowledge of indigenous communities and culture, and curriculum development in Traditional Ecological Knowledge (TEK).
Apriori Algorithm and Market Basket Analysis to Uncover Consumer Buying Patterns: Case of a Kenyan Supermarket
Authors: Omol Edwin Juma , Onyango Dorcas Awino , Mburu Lucy Waruguru , Abuonji Paul Anyango
Published: December 2024

This article presents a study on utilizing the Apriori algorithm and Market Basket Analysis (MBA) to reveal consumer buying patterns in supermarkets. The aim of this research is to explore the effectiveness of these data mining techniques in revealing valuable insights that can inform marketing strategies and enhance the overall shopping experience for customers. This study centered on improving customer loyalty within the supermarket setting through the utilization of cutting-edge information technology and programming applications, including Python. Specifically, the Apriori algorithm libraries of the Python language were employed to identify frequent item sets and derive 42 association rules, which shed light on product affinities and co-purchasing patterns. By deriving association rules from the frequent item sets, the study identified the significance of strategically placing frequently purchased products to enhance revenue generation. In conclusion, the application of the Apriori algorithm and Market Basket Analysis in this case of a Kenyan supermarket has proven to be a valuable approach for uncovering consumer buying patterns, providing a competitive edge in the dynamic retail industry.
Drosophila Sirtuin 1 plays a neuroprotective role in altering Alzheimer’s disease-related pathologies in flies
Authors: Bhatt Vidhi , Tiwari Anand Krishna
Published: December 2024

Sirtuin, a Class III histone deacetylase enzyme dependent on nicotinamide adenine dinucleotide, plays a pivotal role in aging and age-related diseases. Numerous studies have highlighted the involvement of sirtuins in Alzheimer’s and other neurodegenerative diseases; however, their molecular mechanisms and possible interactions with Alzheimer’s disease (AD)-associated genes remain unclear. In this study, using a Drosophila melanogaster model of AD, we investigated the potential genetic interactions between sirtuin and AD-associated genes, including amyloid-beta 42, Appl, and Tau. Our findings show that the overexpression or downregulation of Drosophila Sirtuin 1 alters AD-related pathologies such as the rough eye phenotype, behavioral impairments, and excessive cell death observed in AD model flies. In addition, the observed rescue of AD pathologies appears to be associated with sirtuin overexpression, which modulates c-Jun N-terminal kinase and Notch signaling pathways in flies. These findings show that Sirtuin1 plays a neuroprotective role in AD.
45-nm CMOS Inverter Transimpedance Amplifier for LiDAR Applications
Authors: Süleyman Eymen
Published: November 2024

This paper presents the design of a low-power, high-gain inverter-based transimpedance amplifier (INV-TIA) tailored for Light Detection and Ranging (LiDAR) applications. LiDAR systems require TIAs that can efficiently convert optical signals into electrical signals, making it crucial to optimize both gain and bandwidth to handle the fast light pulses involved. The design proposed in this study addresses these needs by balancing high gain with wide bandwidth, ensuring robust performance across a range of operational conditions. A comprehensive review of similar designs led to the decision to implement the TIA using advanced 45 nm CMOS technology, which offers the advantages of compactness, energy efficiency, and high-speed performance. The circuit operates with a low 0.83 V DC power supply, consuming only 245 µW, which is ideal for portable and battery-powered LiDAR systems. Extensive SPICE simulations using the 45 nm CMOS library were conducted to validate the design. The TIA was evaluated under two scenarios: in high-gain mode, the circuit achieves a transimpedance gain of 91 dB and a bandwidth of 114 MHz, while in low-gain mode, the gain drops to 82 dB, but the bandwidth expands significantly to 297 MHz. These results demonstrate the potential of the proposed INV-TIA for efficient, high-performance LiDAR systems, offering both low power consumption and versatility.
Implementasi Activity Based Costing sebagai Solusi untuk Meningkatkan Efisiensi Biaya di UMKM Tempe Kembar Jalan Pattimura Bawah, Pematangsiantar
Authors: Annisa Fitri Anggreini  , Butarbutar Sonia A , Mutih Arya  , Simbolon Pirma
Published: November 2024

Penelitian ini bertujuan untuk menganalisis efektivitas implementasi metode Activity Based Costing (ABC) dalam meningkatkan efisiensi biaya produksi di UMKM Tempe Kembar jalan Pattimura Bawah Pematangsiantar, dengan implementasi metode Activity Based Costing (ABC). Metode penelitian yang digunakan dalam penelitian ini adalah metode kuantitatif. Cara Pengumpulan Datanya dengan cara Observasi dan wawancara. Dari hasil perhitungan harga pokok penjualan dengan menggunakan metode Activity Based Costing menunjukkan HPP Tempa Kembar per unitnya sebesar Rp1.221,33. Dengan menggunakan metode ABC ,UMKM Tempe Kembar dapat lebih memahami kontribusi setiap aktivitas terhadap biaya total produksi. Metode ABC memberikan gambaran lebih mendalam tentang alokasi biaya berdasarkan aktivitas spesifik, sehingga memungkinkan UMKM Tempe Kembar untuk mengidentifikasi aktivitas dengan biaya tinggi, mengurangi biaya overhead, optimasi distribusi, dan pengambilan keputusan yang lebih akurat
Eco - Handloom Weaver: Retailers Perspective In New Product Development Hiou Simalungun
Authors: Saragih Liharman , Nasution Yanti Jesika , Ginting Vina Depi Cintya , Manik Carolin Agrifa
Published: November 2024

The article aims to explore new product development, particularly in the Hiou industry in Simalungun, by involving various instruments that consist of new product development strategies, development processes, organizational relationships with new product development, and the evaluation of new product performance itself. The research results show that 57.14% of respondents agree that New Product Development is aimed at meeting the demands of traders, and the Objective of New Product Development is to meet the demands of traders, with 32.14% agreeing and 40% agreeing that new product development is carried out after obtaining approval from external parties
ANTECEDENT AND CONSEQUENCES OF CUSTOMER SATISFACTION OF LOCAL FAST FOOD IN INDONESIA
Authors: Sugiarto Yonatan Stenly , Pratomo Luki Adiati
Published: November 2024

The aim of this research is to analyze the positive influence of customization, entertainment, trendiness, interaction on purchase intention, the positive influence of customization, entertainment, trendiness, interaction on customer satisfaction, consumer satisfaction on purchase intention. The data analysis method in this research applies the structural equation model (SEM), is a powerful multivariate tool for analyzing research hypotheses via AMOS ver 23. The expected results in this research are concluded as follows: Customization has a positive effect on purchase intention, Entertainment has a positive effect on purchase intention, There is no positive effect of trendiness on purchase intention, There is no positive effect of interaction on purchase intention, Customization has a positive effect on customer satisfaction, Entertainment has an effect positive effect on customer satisfaction, Trendiness has a positive effect on customer satisfaction, There is no positive effect of interaction on customer satisfaction, Customer satisfaction has a positive effect on purchase intention. This research can provide input and recommendations for further research by adding independent variables, namely food quality and physical environment quality, then it would be better to add other local fast food in Indonesia
COMPARATIVE EFFECTIVENESS OF VARIOUS FERTILIZERS IN CONTROLLING ROOT KNOT NEMATODE INFECTION IN OKRA (Abelmoschus esculentus) IN MAKURDI, BENUE STATE
Authors: Olusesan Adepoju Isaiah , Ene Danladi Mary
Published: November 2024

Root knot nematode infection poses a serious threat to Okra cultivation in Nigeria. A field research was conducted at the Teaching and Research Farm of the Federal University of Agriculture, Makurdi, Benue State to offer valuable insights into combating root-knot nematode infections on okra using different fertilizer types. The experiment was designed using a factorial design with three (3) varieties of okra and two fertilizer treatments at different intervals. The seeds were planted two (2) seeds per hole on a spacing of 50cm after which normal agronomic practices were carried out on nematode infested soil. The results indicate that both SuperGro liquid fertilizer and Geese dung have potential in suppressing root-knot nematode infections on okra. Specifically, the application of Geese dung at either 2 or 4 weeks interval demonstrated a notable reduction in root gall index (RGI), suggesting its effectiveness in mitigating nematode damage. Furthermore, the application of Geese dung led to improved yield, manifested through increased fruit size and quantity. However, it's crucial to note that the application of SuperGro fertilizer at a 4-week interval resulted in a significantly higher Root Gall Index (RGI) compared to other treatments. The research highlights the potential of organic fertilizers like Geese dung as a sustainable and effective means of nematode control in okra cultivation. Nonetheless, future studies are warranted to identify the active ingredients in Geese dung responsible for nematode suppression, which could provide valuable insights for refining treatment protocols and enhancing agricultural practices.
VARIABILITAS FENOTIPE GALUR HARAPAN MENTIMUN (Cucumis sativus) BUAH KECIL BERWARNA HIJAU SEDANG GENERASI 3
Authors: Alim Ahmad Fathul , Rajiman Rajiman , Aziza Elea Nur
Published: November 2024

Tujuan penelitian untuk mengetahui variabilitas karakter fenotipe mentimun galur harapan ukuran buah kecil berwarna hijau sedang generasi 3. Penelitian  telah dilaksanakan bulan Maret - Mei 2024 di Teaching Factory Karangsari, Wedomartani, Ngemplak, Kabupaten Sleman, Daerah Istimewa Yogjakarta. Materi yang digunakan dalam penelitian ini adalah 3 varietas mentimun yaitu AGB KE 0316, KE 4723, dan 01.08. Metode penelitian menggunakan rancangan percobaan single plant yaitu dengan menanam dan mengamati setiap individu tanaman hasil persilangan. Analisis data karakter kualitatif mengacu pada pedoman dengan deskriptif. Analisis data keragaman dianalisis dengan dendogram. Hasil penelitian dari variabilitas galur harapan yang diamati diperoleh 3 klaster yang dihasilkan yaitu klaster kulit buah hijau sedang, hijau sedang bentuk ujung buah runcing, dan hijau terang menghasilkan dendogram dengan koefisien tingkat kemiripan 0-50 %. Hal ini disebakan karena terdapat perbedaan keragaman pada bagian bentuk daun, intensitas warna dasar kulit dan bentuk ujung buah. Kode tanaman terpilih dalam penelitian ini adalah 01.08.05 dengan sifat kecil dengan memiliki karakter kulit buah berwarna hijau sedang. The study aims to determine the variability of phenotypic characters of cucumber small green fruit size hopeful strains of generation 3. The research was conducted in March - May 2024 at Teaching Factory Karangsari, Wedomartani, Ngemplak, Sleman Regency, Special Region of Yogyakarta. The materials used in this study were 3 cucumber varieties namely AGB KE 0316, KE 4723, and 01.08. The research method used a single plant experimental design by planting and observing each individual plant of the cross. Data analysis of qualitative characters refers to the guidelines with descriptive. Data analysis of diversity was analysed by dendrogram. The results of the research from the variability of the observed hope strains obtained 3 clusters, namely the cluster of medium green fruit skin, medium green pointed fruit tip shape, and bright green produced a dendrogram with a similarity level coefficient of 0-50%. This is because there are differences in diversity in the shape of the leaves, the intensity of the basic colour of the skin and the shape of the tip of the fruit. The selected plant code in this study is 01.08.05 with a small trait with a medium green fruit skin character.
Workplace Incivility in Hotels: Unmasking the Complex Landscape of Employee Well-Being
Authors: Emmanuel E.Christopher , Das Madhumita
Published: November 2024

Workplace incivility in hotel settings poses significant challenges, affecting employee well-being and organizational outcomes. This systematic literature review aims to comprehensively examine its multifaceted impact, addressing key research questions. Firstly, it explores the antecedents
and forms of workplace incivility. Secondly, it explores the multilayered impacts on employee well-being, job satisfaction, engagement, turnover intentions, and counterproductive behaviors. Lastly, it examines how leadership styles, organizational support structures, individual traits, and
contextual variables influence employee responses to incivility. Through a SLR methodology, current trends and gaps in research are identified, offering insights for future examination. The review includes 102 relevant papers to the study, covering the time range from 2012 to 2023. The application
of the PRISMA methodology and SPAR4-SLR approach ensures a detailed analysis of published works, while the TCM framework provides a theoretical lens for interpretation. This review contributes to a deeper understanding of workplace incivility dynamics in hotel settings, informing both research
and practical interventions. Findings suggest that positive leadership and strong organizational support mitigate the negative effects of incivility, while negative factors like nepotism exacerbate them. Enhancing emotional intelligence and establishing clear anti-incivility policies are crucial
for improving employee well-being and organizational success.
Molecular Landscape of Colorectal Cancer: Clinical Significance of Typical and Atypical Mutations
Authors: Телетаева Гульфия Мидхатовна , Дегтярёва Екатерина Александровна , Семенова Анна Игоревна , Семиглазова Татьяна Юрьевна , Малыгин Артур Юрьевич , Иевлева Аглая Геннадиевна , Имянитов Евгений Наумович
Published: December 2024

Молекулярно-генетическое исследование опухолевого материала при колоректальном раке (КРР) необходимо для обоснованного выбора лекарственной терапии. Решающее значение для пациентов с диссеминированным процессом имеет оценка статуса генов RAS, BRAF, HER2, а также микросателлитной нестабильности (MSI). К более редко встречающимся молекулярным маркерам, которые могут повлиять на выбор терапевтического подхода, относятся мутации в гене POLE и перестройки с участием тирозинкиназ NTRK1-3, RET и ALK. В настоящем обзоре представлена краткая информация о встречаемости перечисленных генетических нарушений при КРР, их ассоциациях с клинико-морфологическими параметрами, а также их влиянии на прогноз заболевания.
ФОРМИРОВАНИЕ ПРИВЯЗАННОСТЕЙ В РАННЕМ ВОЗРАСТЕ. ИХ ОСОБЕННОСТИ И НАРУШЕНИЯ ПРИВЯЗАННОСТИ
Authors: О.В. Живец
Published: December 2024

Статья посвящена анализу основных типов привязанности, их формированию и нарушениям. Рассмотрено влияние привязанности на развитие личности. Сопоставлены типы привязанностей, описанные в зарубежных (Дж. Боулби, М. Эйнсворт, М. Мейн, А. Кернс) и отечественных (Н.Н. Авдеевой, Н.А. Хаймовской, Т.В. Казанцевой) теориях. Изучены исследования о формировании привязанности и связи её нарушений с деструктивным поведением.
CREATING NEW ABILITIES WITH LANGUAGE
Authors:   Independent Researcher, Ottawa, Canada, Douglas Reid Watson
Published: November 2024

This article explains how new abilities are acquired when speaking a language that I call the Soral language. The language is created with the aid of computer technology that organizes the words in a way that enables our brain to attach meaning to the sound of the words. The following abilities are acquired when speaking the language.
1. The ability to understand the meaning of words that have never been heard before or seen in a book.
2. Improved ability to recall words from memory.
3. Larger vocabulary.
4. Improved conversational skills.
5. Improved understanding of the meaning of words.
6. Ability to understand medical and other technical terms without formal training.
7. Ability to learn the Soral language more easily than other languages.
Words in the Soral language are created by entering words in one of our existing languages into the computer program, then clicking buttons which are hyperlinked to other pages containing more buttons. Each button describes one characteristic of the entity that the word represents. A letter is assigned to each characteristic. By clicking on several buttons in succession a word is created that has a sound that represents the characteristics of the entity that the word represents. Speakers of the language can understand the meaning of words by the sound of the word. It is proposed that the Soral language should be adopted as a universal language.
Ultrablack color in velvet ant cuticle
Authors: Lopez Vinicius Marques , Krings Wencke , Machado Juliana Reis , Gorb Stanislav , Guillermo-Ferreira Rhainer
Published: December 2024

We studied the ultrastructure of the ultrablack cuticle in Traumatomutilla bifurca, an enigmatic and visually striking species of velvet ants (Hymenoptera, Mutillidae). Using a combination of scanning electron microscopy (SEM), transmission electron microscopy (TEM), confocal laser scanning microscopy (CLSM), and optical spectroscopy, we conducted a comprehensive analysis of the cuticle to elucidate its unique optical properties. SEM imaging provided a detailed surface morphology, while TEM provided insights into the internal structure. CLSM showed that the cuticle exhibits no autofluorescence. Our findings reveal a highly specialized cuticle, characterized by microstructures that effectively minimize reflectance and enhance light absorption. Optical spectrometry confirmed the ultrablack nature of the cuticle, with the measured reflectance approaching minimal levels across a broad spectrum of wavelengths. Therefore, our study contributes to a deeper understanding of ultrablack biological materials and their potential applications in biomimetics.