bluuebunny/crossref_metadata_2025 huggingface dataset:
Essai de formulation de suppositoires à base d’extraits aqueux des écorces de tronc de Parkia biglobosa jacq. (Fabaceae-Mimosoideae) pour la prise en charge de l’inflammation due à la crise hémorroïdaire
Authors: Atchadé Boladé Constantin , Ouédraogo Salfo , Traoré Tata Kadiatou , Yaméogo B. Gérard Josias , Sombié Bavouma Charles , Zimé-Diawara Hermine , Ouédraogo Noufou , Semdé Rasmané
Published: July 2024

La maladie hémorroïdaire est un état pathologique caractérisé par une dilatation de la veine recto-anale plexus. Une enquête ethnobotanique a révélé l’utilisation des écorces de tronc de Parkia biglobosa (Jacq.) sous forme de pommade ou décoction en lavement anal pour son traitement. L’objectif de cette étude était de caractériser l’extrait afin de formuler des suppositoires. Un screening phytochimique et une caractérisation physico-chimique suivi évaluation de l'activité antioxydante et antiinflammatoire de l’extrait ont été réalisés. Une formulation des suppositoires a été définie à partir d’une stratégie utilisant deux masses à suppositoire (Witerpsol H15 et Suppocire ASX2). Les suppositoires obtenus ont fait l’objet de contrôle qualité et d’évaluation de l’efficacité. L’extrait était de couleur marron avec une texture fine. Son taux d’humidité était à 4,67 et le pH de 7,17. Les suppositoires avaient une forme allongée, une texture et un aspect uniforme avec un temps moyen de ramollissement de 8,36min et un point de fusion moyen de 37,3°C. L’étude phytochimique a permis de mettre en évidence des flavonoïdes. L’évaluation de l’activité antioxydante a donné une concentration inhibitrice (IC50) de  9,35 µg/ml Par ABTS, un pourcentage d’inhibition de 54,34% par LPO et l’activité Antiinflammatoire par l’inhibition de la LOX avec une IC50 de 19,01 µg/ml. Les études réalisées offrent une alternative d’utilisation de l’extrait sous forme de suppositoires pour le traitement de l’inflammation de la maladie hémorroïdaire.
Application of polyethylene glycol 8000 as plasticizer for the development of ellagic acid and Eudragit® EPO based solid dispersions using hot melt extrusion.
Authors: Nyamba Isaie , Nembot Alexis M W , Sombié Bavouma Charles , Zimé-Diawara Hermine , Yaméogo B. G. Josias , Lechanteur Anna , Damblon Christian , Semdé Rasmané , Evrard Brigitte
Published: July 2024

Solid dispersion formation by Hot melt extrusion (HME) is a widely used formulation strategy to improve the solubility and bioavailability of poorly water-soluble drugs. Despite this, they are limited by various factors such as drug-excipient miscibility, poor stability, limited drug loading and extrudability of physical drug-excipient mixtures. In this work, polyethylene glycol 8000 (PEG 8000) was used as a plasticizer for the manufacture of ellagic acid solid dispersions (EASD) with high drug loading. Indeed, EA is a polyphenolic active compound with antimalarial and other promising therapeutic activities. However, its low solubility and low permeability limit its therapeutic use. Solid dispersions formation may overcome this challenge, but its high melting point negatively influences the extrudability of its binary physical mixtures with a high drug loading rate, hence the need to use a plasticizer. Thus, five formulations consisting of EA, Eudragit® EPO and PEG 8000 in the ratio of 15:75:10 (F1), 20:70:10 (F2), 25:65:10 (F3), 15:80:5 (F4) and 20:85:5 (F5) % w/w, respectively, have been extruded, four of which were successful. The extrudates were evaluated by X-ray powder diffraction, FTIR spectroscopy and in vitro dissolution tests. Based on the results of these tests, the F5 formulation was identified as the most promising. Indeed, after 15 min of dissolution test, the dissolution rate of ellagic acid from the formulations was 62.67±3.10%, 58.74±7.23 %, 88.75±3.02% and 83.47±4.40% respectively for formulation F1, F2, F4 and F5. Moreover, the results of the FTIR spectroscopy analyses showed stronger interactions between the different constituents in the F4 and 5 formulations compared to the F1 and 2 formulations. Extruded materials of the F5 formulation, characterized by solid state nuclear magnetic resonance (ssNMR) spectroscopy and subjected to stability studies, showed good physical stability for twelve months under real-time stability study conditions and for six months under accelerated conditions.
Effects of Aerobics Exercise on Body Mass Index (BMI) and Mental Health Among Obese College Students
Authors: Yang Wang , Zainuddin Zainal Abidin
Published: July 2024

Background: Aerobic exercise plays an influential role in improving mental health. Aerobics, as a form of efficient aerobic exercise, is suitable for various individuals and promotes the mental health of college students. Objectives: The purpose of this study was to explore whether aerobic exercise has a positive effect on the mental health and Body Mass Index (BMI) of obese college students. Methods: Sixty obese college students with a BMI ≥ 28 were selected and divided into two groups. Each group consisted of 30 students, 15 boys and 15 girls. The experimental group received aerobic exercise training three times a week for 12 weeks, while the control group received prescribed aerobic training. Data before and after the experiment were recorded. Results: The BMI of the experimental group decreased from 30.19 ± 0.73 before the experiment to 27.32 ± 0.84 after the experiment, with a change range of 2.86 ± 0.11. The experimental group showed significant differences before and after the experiment (P < 0.01). The BMI of the control group decreased from 30.16 ± 0.73 before the experiment to 28.62 ± 0.89 after the experiment, with a change range of 1.54 ± 0.84. The control group also showed significant differences before and after the experiment (P < 0.05). The experimental group had a better effect. The 12 dimensions of the mental health test changed in both the experimental group and the control group, and the results were statistically significant (P < 0.05), with the experimental group showing better improvement. Conclusions: The statistically significant impact of aerobics on the mental health of obese college students holds practical significance. Notably, the observed reduction in anxiety and depression symptoms, coupled with notable enhancements in self-esteem and self-confidence, underscores the tangible benefits of incorporating aerobics into the lifestyle of this demographic.
The Success Factors of Small Business in Crisis Condition: A Systematic Review
Authors: Zulfa Inayati Fadhilah , Zuraida Umi , Muthahhari Muwahid
Published: July 2024

This systematic review examines the success factors of small businesses, particularly Micro, Small, and Medium Enterprises (MSMEs), during economic crises. Utilizing a systematic literature review (SLR) approach, the study identifies key elements that contribute to business resilience and performance in adverse conditions. The research highlights that physical and mental health, excellent customer service, support from family and friends, effective cash and liquidity management, adaptability, technology adoption, government support, and innovative business models are crucial for MSMEs' success during crises. The review further discusses how these factors enable businesses to navigate uncertainties, maintain operations, and thrive. This study aims to provide actionable insights for entrepreneurs, policymakers, and researchers to support small businesses in crisis conditions, fostering economic recovery and stability.
Leibniz on the Contingency of the Laws of Motion
Authors: Chiek Yual ,   The Leibniz Society of North America
Published: July 2024

In a few key texts Leibniz points to his dynamics project as the origin of contingency in his system. He did not, however, leave us with an explicit account of how the distinction between necessary and contingent truths either arises from, or is explained by his dynamics. This has left an explanatory gap in our understanding of the connection between Leibniz’s physics and his modal metaphysics that scholars have sought to close by arguing that the laws of nature obtain their contingent status by virtue of being derived from the principle of the equality of cause and effect (‘Equality Principle’); a principle that is itself contingent. I call this view the ‘Transference of Contingency Thesis’ (TC). In this paper I show that TC is wrong by advancing the claim that the equality principle is, in fact, a ‘contingent necessity.’
The Unconscious in Personalism
Authors: Caro Plaza Ramón ,   Saint Louis University
Published: July 2024

Although Freud presented his theory of the unconscious as a groundbreaking innovation, we find remote antecedents. This article analyzes the approach of personalist psychology, which offers three unconscious instances: sensible, intellective, and volitional. I trace this approach back to the tradition initiated by Plato and progressively developed by kindred thinkers up to modern times. In particular, I highlight the contributions of Aristotle, Augustine, Aquinas, and Rosmini. To conclude, I show that their earlier conception of the unconscious corresponds to the general characteristics of the Freudian notion while also differing radically in their ontological significance and anthropological implications.
Resiliensi Pasien Diabetes Mellitus Tipe 2 dalam Menjalani Diet di Wilayah Kerja Puskesmas Madurejo
Authors: Zuliya Indah Fatmawati  , Wahyudi Qorahman MM  , Eko Budi Laksono
Published: July 2024

Diabetes mellitus is a degenerative disease that is currently experienced by many in developing countries and is found in many countries in the world. Diet for diabetes mellitus is a non-pharmacological management that often creates a feeling of boredom, so the resilience of diabetes mellitus patients needs to be considered. The aim of this study was to determine the level of resilience of type 2 diabetes mellitus patients in undergoing a diet. The research results showed that 57.39% of respondents had good resilience, 34.2% had sufficient resilience and 7.9% had less resilience. Most of the respondents in this study were female with a percentage of 52.6% and the majority of respondents' last education was high school with a percentage of 44.73%. The results of this study concluded that the majority of respondents had good resilience and it still needs to be improved to minimize the risk of complications, both macrovascular and microvascular.
Perceived Effects of Fallouts of the 2023 General Elections on Orientation of Tertiary Education Students in Imo State
Authors: Nnajieto Charles Chibuzor , Iwejuo Christogonus Amara
Published: July 2024

This study investigates the perceived effects of the 2023 general elections on the orientation of undergraduate students in Imo State, Nigeria. Given the fundamental role of credible, free, and fair elections in a democracy, this research aims to gauge the opinions of young Nigerians, particularly those in higher education institutions, who are presumed to be more enlightened and actively involved in their Student Union Governments. Adopting a public opinion survey design, the study utilized a stratified sampling technique to distribute questionnaires among the respondents. The collected data, representing public opinion polls, were analyzed to discern prevailing sentiments. Results indicate a significant disillusionment among undergraduates, with many expressing a loss of confidence and interest in Nigeria's electoral system. The study reveals that the majority of students believe that the Independent National Electoral Commission (INEC) has failed the citizens, particularly in light of the high expectations set by the introduction of the Bimodal Voter Accreditation System (BVAS), which promised transparency but ultimately did not fulfill its potential. This disillusionment has led to a widespread desire among young Nigerians to emigrate in search of better governance. The study recommends that electoral bodies prioritize restoring the integrity of democratic institutions by ensuring the conduct of credible elections in Nigeria.
Opinions of Health Professionals about the Management of Vaginal Deliveries: A Qualitative Research
Authors: Amanak Keziban , Şeker Sibel , Çitil Canbay Funda , Serçekuş Pınar
Published: July 2024

The research aimed to identify the opinions of health professionals working in the field of obstetrics about the management of vaginal deliveries. The research was carried out with 18 health professionals having active duties in vaginal deliveries at a state university hospital in western Turkey. The maximum variation sampling method, one of the purposive sampling methods, was used. The research data were collected through information form and structured information form. They were analyzed through the thematic analysis method. Ethic Approval was received. Three main themes were identified about the management of vaginal deliveries in this research. (I) opinions of midwives about the management of vaginal deliveries, (II) opinions of nurses about the management of vaginal deliveries and (III) opinions of doctors about the management of vaginal deliveries. The participants (especially midwives and doctors) stated that they overall viewed themselves as a significant activist in the responsibility for vaginal delivery, and midwives could carry out vaginal deliveries due to the workload and the fact that the pregnant women were followed up by midwives. Midwives and nurses emphasized that delivery was not only a medical action but also brought significant responsibilities requiring active care in pregnancy, delivery and the postpartum. The perspective of health professionals was mainly in the direction of the fact that all midwives, who had sufficient education and skills, could carry out vaginal deliveries independently. They agreed that the team who would carry out the delivery should be given continuous institutional training in terms of theory and practice. It is necessary that active studies should be planned on matter of the fact that especially the nurses and midwives in university hospitals could carry out their independent duties and increase their responsibilities for vaginal deliveries as a part of a team.
HOW THE SOMALI MODERN GOVERNANCE WORKS WITH THE TRADITIONAL GOVERNANCE SYSTEM: LITERATURE REVIEW
Authors: Warsame Afifa
Published: July 2024

Somalia, located in the Horn of Africa, has a complex history influenced by tribalism, colonialism, and internal conflict. During the colonial era, European powers collaborated with clan leaders, resulting in Somalia's division along clan and tribal lines. This division led to the creation of artificial borders, which fragmented the land and fostered regional and clan-based identities. After gaining independence in 1960, Somalia initially aimed to establish a strong, centralized state. The Siad Barre regime, which came to power through a military coup in 1969, tried to suppress clan and regional identities in favor of a communist ideology. However, the regime's downfall in 1991 plunged Somalia into a prolonged period of violence and state collapse. Warlords and clan-based factions fought for power, leading to a protracted civil war. This paper analyzes the intricate relationship between Somalia's traditional and modern governance systems. It examines the potential for collaboration, the challenges faced in nation-building efforts, and the lasting impact of clan-based structures. The study begins by exploring traditional governance, highlighting the important role of customary law, elders, and religious clerics in consensus-building mechanisms and maintaining social harmony. It emphasizes the historical significance and contemporary relevance of these institutions. The paper then delves into the challenges involved in establishing a modern state in Somalia. It examines the obstacles that hinder the realization of democratic ideals and the establishment of a centralized administration. A key focus is evaluating the potential synergies and conflicts between traditional and modern systems.
A dimensão emocional da cognição: de Schopenhauer à psicologia moderna
Authors: Oliveira André Henrique M. V. de , Lima Filho Ferdinand de Oliveira
Published: July 2024

Por meio de pesquisa teórico-bibliográfica, e de caráter sistemático, analisamos a relação entre o aspecto volitivo (vontade) e o aspecto lógico-racional no contexto de debates argumentativos, utilizando como ponto de partida para isso a filosofia do pensador alemão Arthur Schopenhauer (1788-1860), em específico a parte de sua obra que envolve a chamada dialética erística, método que concerne à arte do debate argumentativo. Partimos dos pressupostos epistemológicos da filosofia de Schopenhauer para em seguida apresentarmos sua concepção de que o conhecimento humano é organicamente dependente das funções mais básicas e gerais do corpo, sendo tais funções direcionadas pelo que Schopenhauer conceitua como vontade, principal conceito de seu sistema filosófico. Estando assim o intelecto humano submetido aos direcionamentos da vontade (impulsos volitivos), procuramos apontar como, no contexto de debates argumentativos, a dimensão pretensamente lógica e racional pode estar submetida à vontade (inconsciente e irracional) do indivíduo que argumenta. Por fim, apresentamos algumas pesquisas correlatas na Psicologia científica, desenvolvidas já a partir do século XX, que apontam para uma forte influência da dimensão emocional sobre a cognição humana, o que corrobora as ideias de Schopenhauer a respeito deste tema.
Exploring EFL Learners Students-Teacher Relatedness
Authors: Al Fatih Ahmad Fiqi , Lestari Lies Amin , Anam Syafi'ul
Published: July 2024

Purpose this study of to know how students’ and teacher views on students and teacher relatedness in the classroom related to vocabulary learning. Specifically, the methodology used in this research was giving the researcher ability to explore students and teacher point of view on the relatedness between them inside and outside classroom. Thus, qualitative research methodology is going to be utilized to achieve the research objective. The subjects of the study were one senior high school EFL teacher, and the students of one class of English language major class consisting of 4 students. The data of this research was obtained using interview questions instrument. The scope of this study is to explore students-teacher relatedness inside or outside the classroom. However, the results of this study might not be able to be generalized. SDT believe parents also has playing role in learners’ success in learning, meanwhile, this research is only focuses on the relatedness between students-teacher. In addition, it would be inconvenient to do research on every parents. The results of this study are expected to give beneficial information for other researcher who conduct study on this similar topic. The results of this study are expected to give beneficial information for the teacher which may giving better attention in the learners learning process by providing support in every chance they have. To the curriculum designer what is learners needs when they conduct vocabulary learning.
King of the Mountain: using R to bag a Strava KOM
Authors: Royle Stephen
Published: July 2024

One of the best features of Strava is the battle to be King (or Queen) of the Mountain. Originally, in cycling, segments were typically climbs or difficult sections of road, and the simple idea, is who can complete the segment in the quickest time. Hence they would be KOM/QOM, King or Queen of the Mountain. Segments quickly expanded to pretty much any section of a course and to include running segments, to separate them from cycling.
STRATEGI PEMASARAN DIGITAL UNTUK MENINGKATKAN PENJUALAN PRODUK LOKAL DIERA ONLINE
Authors: Silaen Karina , Eddy Bachtiar Lasman , Silaen Montaris , Parhusip Arisman
Published: July 2024

Pengabdian ini bertujuan untuk mengidentifikasi dan menganalisis strategi pemasaran digital yang efektif dalam meningkatkan penjualan produk lokal di pasar online. Metode Pengabdian yang digunakan meliputi studi literatur, survei kepada pelaku bisnis lokal, dan analisis data dari platform digital. Hasil Pengabdian menunjukkan bahwa penggunaan media sosial, optimasi mesin pencari dan pemasaran konten memainkan peran penting dalam memperluas jangkauan pasar dan menarik pelanggan potensial. Selain itu, integrasi e-commerce dengan strategi pemasaran digital seperti iklan berbayar (PPC), email marketing, dan influencer marketing juga terbukti efektif dalam meningkatkan penjualan. Pengabdian ini menyimpulkan bahwa keberhasilan strategi pemasaran digital tergantung pada pemahaman mendalam tentang target pasar, adaptasi terhadap tren digital terbaru, dan konsistensi dalam pelaksanaan kampanye pemasaran. Implikasi praktis dari Pengabdian ini memberikan panduan bagi pelaku bisnis lokal untuk mengoptimalkan strategi pemasaran digital mereka, sehingga dapat bersaing secara efektif di pasar online.
Kata Kunci: Pemasaran Digital, Produk Lokal, Penjualan Online, Media Sosial, E-Commerce
Nursing approach to the management of type 2 diabetes mellitus
Authors: Godoy Cagua Ana Nereida , Granja Ati Nataly Silvana , Enríquez Jácome Miguel Ángel , Morales-García Wilter C.
Published: July 2024

The management of type 2 diabetes mellitus is a global challenge due to its high prevalence and complications. From a nursing perspective, a holistic approach is required that includes education, follow-up and support to promote self-care and adherence to treatment, considering the specific needs of each patient. Nurse-led interventions using mobile technology, educational and psychological support programs, and telenursing strategies have been shown to improve self-efficacy, treatment adherence, and glycemic control. However, more research is needed to assess long-term sustainability and optimize these strategies in different sociocultural contexts. Health policies should integrate these practices to effectively address this chronic disease.
Dental complications due to the use of bisphosphonates
Authors: Miranda Rosero Oswaldo Damian , Paredes Herrera Maria Eugenia , Miranda Fernandez Josselyn Eliss , Pujos Pérez Julio César
Published: July 2024

Objective: The main objective of this article is to describe dental complications due to the use of bisphosphonates through a bibliographic review. In turn, this objective had the following specific objectives: a) Identify the treatments in patients administered bisphosphonates, and b) Know the types of bisphosphonates most used associated with dental complications. Materials and methods: This research uses a qualitative approach, which developing through documentary-type research to describe the points raised in the objectives. A systematic review carrying out applying the PRISMA methodology, where the Scopus and PubMed databases using to search for the information in documents published between January 1, 2018 and January 31, 2023 to select the appropriate ones according to inclusion and exclusion criteria. Results: From 11897 initially identified articles, only nine articles met all the eligibility criteria for this study. The selected articles are of high impact belonging to journals within quartiles 1 and 2. Among the most outstanding findings is that the use of antiresorptive therapies with bisphosphonates cause dental complications such as osteonecrosis of the jaw and risks in cases of dental extractions. In addition, the most widely used type of bisphosphonate is zoledronate, the major cause of osteonecrosis of the jaw. Conclusions: Antiresorptive therapies with the use of bisphosphonates, especially with the administration of zoledronate, are the main causes of osteonecrosis of the jaw
Mechanisms of infection and immune evasion of Trichinella spiralis, a Literature Review
Authors: Moya Melany Michelle Abril , Carrera Aldaz Graciela Alexandra , Poveda Paredes Francisco Xavier
Published: July 2024

Trichinosis begins when a person eats raw or undercooked meat that contains Trichinella larvae. Once inside the digestive tract, the larvae break free and break through the intestinal wall, entering the blood and lymphatic vessels. They then migrate through the bloodstream and spread to various tissues in the body, such as muscles, where they continue to develop.
Once the larvae reach the muscles, they develop into an immature stage called "infective muscle cells" or "coil cells." These cells are surrounded by a protective capsule, formed by the inflammatory reaction of the host. Within these capsules, the larvae evade the host's immune response and become highly resistant to destruction.
Trichinella is capable of evading and modulating the host's immune response. The larvae release molecules that can inhibit the activation of cells of the immune system and reduce the production of proinflammatory cytokines, which contributes to the persistence of the parasite in muscle tissue. The presence of the larvae encapsulated in the muscles can cause tissue damage, inflammation and muscle pain.
Trichinella pathogenicity mechanisms are also related to its ability to complete its life cycle. When an infected host dies, the larvae are released back into the muscles and can infect other carnivorous animals that eat their meat, thus closing the cycle
Importance of intracanal calcium hydroxide medication between sessions in chronic dentoalveolar abscesso (clinical case)
Authors: Diaz Espinoza German , Ibarra Ramirez Maria Belen , Urrego Cueva Gladys Viviana , Reyes Espinoza Libia Karina
Published: July 2024

A fistula is, by definition, the opening in the mucosa or skin of a drainage route that the body itself creates, to allow purulent material to exit into the external environment and allow the natural drainage of an abscess. A simple and effective way to identify the dental piece of origin of the fistula is to slowly insert a disinfected #25 diameter gutta-percha point through the fistula in order to diagnose and collect important data to later be analyzed and interpreted, allowing evaluation in What conditions is found in the tooth that will subsequently receive endodontic treatment.
Pulp pathologies caused by anaerobic and aerobic microorganisms present in the oral cavity can be successfully treated most of the time when the patient arrives opportunely to the dental office. Some of the symptoms that can be presented on a daily basis to the clinician are the various pathologies that can alter the root pulp of the dental groups.
However, the clinician must be prepared and differentiate these pathologies in order to effectively and timely address these dental pathologies, reducing the present symptoms and thus stimulating the repair process of the periapical tissues, restoring its functionality and aesthetics of the treated tooth. endodontically.
On the other hand, periapical pathologies can enter a mild process and become a chronic process, affecting even the soft tissues of the oral cavity. However, the professional must know the anatomical complexities found in root canal systems, through a meticulous and exhaustive examination, know how to identify pulp symptoms, incorporating complementary examinations, such as conventional radiography, conical feixe computed tomography, which It will provide the clinician to obtain a more exhaustive diagnosis, thus having a treatment plan, prognosis of this, raising the percentage of successes in endodontic treatments
Patient safety management at the Santo Domingo General Hospital
Authors: Mihalache Bernal Lexter Iván , Carlos Alberto Valverde González Carlos Alberto Valverde González , Pinza Vera Vanessa del Cisne
Published: July 2024

The management of patient safety is a priority in health institutions for the execution of safe practices that guarantee that the patient does not experience unnecessary or potential harm associated with health care. The present study evaluated the management of patient safety at the Santo Domingo General Hospital, during the year 2022. It was structured as a quantitative study, with a descriptive, exploratory and field approach, due to the use of instruments that collect information from the sources. study primaries. The questionnaire of the Agency for Health Care Research and Quality and the structured interview with the director of the institution were used as methodological tools. The sample was made up of 100 professionals from the operating population and an administrative director. Where labor, social and personal parameters were included, evaluated in 5 security categories. Highlighting that 65% of health personnel determined that the guidelines of the patient safety program are fully complied with. Concluding that, even when the management of patient safety in this institution is efficient, continuous training and the inclusion of updating parameters that adapt to the needs of the establishment are necessary, and thus improve the culture of patient safety
Functional Mitral Regurgitation of Atrial Etiology
Authors: Jurado Carrera Pablo Danilo , Muñoz Padilla María Belén , Vega Martínez Verónica Alicia
Published: July 2024

Mitral regurgitation is the most prevalent valve disease within heart valve problems. The etiology has been framed in a primary and secondary component. The secondary component for a long time has been related to both the dilation of the ventricular cavity and, in turn, the mitral annulus. Functional atrial mitral regurgitation has taken a new direction in its interpretation since dilatation of the left atrium has now also been associated with the interpretation of a new mechanism when the dimensions of the left ventricular cavity are preserved.
The importance of interpreting the etiology, pathophysiology, diagnosis and treatment have defined a new and better way of interpretafion
Prevalence and treatment of oral cancer in older of Latin America
Authors: Aurelia María Cleonares Borbor Aurelia María Cleonares Borbor , Armijos Moreta Jaime Fernando , Vera Veloz Amalia Fernanda
Published: July 2024

This research has as main objective to identify the prevention factors of oral cancer, it was in an exploratory and documentary way a recent scientific literature focused on the prevalence of oral cancer in adults in Latin America, the investigative universe was grouped by their age, sex, origin, oral topography, clinical extension and morphological type, evidencing that men are more prone to contract the disease, between 50 and 79 years, while women vary between 50 and 54 years. In addition to this, it was possible to obtain the risk factors that most intervene, which are varied. Oral cancer can cause permanent sequelae in the life of a sick person, resulting in severe difficulties in oral function, such as language and chewing. Its early detection results in a more favorable prognosis
Molar Pregnancy with Live Fetus
Authors: Ramos Villacís Ruth Alexandra , Ramos Velastegui Alexander Javier , Maldonado Mariño Edisson Vladimir , Chiguano Vega Evelyn Sofía
Published: July 2024

During pregnancy, the immune response undergoes adjustments, tending mostly to preserve the new being in development, therefore, the hydatidiform mole coexisting with a live fetus is a rare entity that is characterized by hydropic degeneration of the chorionic villi and the trophoblast hyperplasia where there is gross evidence of a fetus. Its objective is to be able to show a clinical case of a twin pregnancy affected by a hydatidiform mole and a live fetus, through a search of a bibliographic review from a year ago, both in Spanish and English. The clinical case of a 28-year-old pregnant woman named Camila Pazmiño is presented, with a gestational age between 26 and 27 weeks, with an obstetric history of G2, P1, A0, who was admitted with a diagnosis of partial molar pregnancy and viable fetus, in addition She refers to a threat of immature labor where a normal delivery is performed, a low-weight newborn that does not survive due to immaturity and mola is extracted in its entirety, obtaining a female newborn, weighing 1000g, and the Apgar score. on 8/10 and transferred to the Neonatology service. Also to rule out that molar pregnancy with a live fetus is of high maternal and fetal risk, for which it is proposed to establish and identify early diagnosis and management through invasive techniques such as amniocentesis or chorionic villus biopsy, and thus be able to carry out follow-up. careful perinatal care, where the interruption of pregnancy must be individualized in each patient and avoid previous complications
Utility of the routine use of coagulation times in non-cardiac elective surgery
Authors: Valverde Gonzalez Carlos Alberto , Mihalache Bernal Lexter Ivan , Pinza Vera Vanessa Del Cisne
Published: July 2024

The purpose of this paper is to determine the utility of the routine use of coagulation times in the preoperative evaluation in patients scheduled for elective non-cardiac surgery, to predict the risk of trans-surgical hemorrhagic complication, for which a systematic review of the type was carried out. quantitative by meta-analysis with search in Health Sciences databases: PubMED, Cochrane Library Plus, Google Scholar, Redalyc and Scielo using DeCS/MeSH terms coagulation times, non-cardiac elective surgery; joined by the boolean operator AND and filters Adults, since 2018, controlled clinical trials. The Jadad scale for risk of bias was applied, as well as to determine the quality of the study. Relative risk was the effect measure for a CI95 and an error of 0.05. Four controlled clinical trials were included, which showed that there is no relationship between bleeding complications and the average values of PT or TTP, since these were not significantly different in both groups
The correlation between bruxism and tooth wear: An in-depth analysis
Authors: Amán Frías Silvana Nathaly , Mayorga Romo Alexandra Elizabeth , Villa Sáez Lisseth Vanessa , Manuel Benites Rolando
Published: July 2024

In today's society, teeth have a dual aesthetic and functional importance in the chewing and digestion of food. However, factors such as bruxism can cause adverse effects such as dental attrition. This research focuses on analyzing the relationship between bruxism and dental attrition. A comprehensive review of the scientific literature was carried out, with a total of 22 recognized database sources. The results confirm a direct connection between bruxism and dental attrition. Bruxism causes gradual wear of the teeth, especially the central incisors and the surrounding tissue, due to abnormal and frequent jaw movements with excessive force, between 100 and 115 kg, generating clashing or grinding sounds.
Clinical manifestations of cystic fibrosis
Authors: Muyulema Muyulema Lissette Estefanía , Olivo Torres Rosita Elizabeth del Carmen , Tobar Armendariz Karen Aracelly
Published: July 2024

Cystic fibrosis is a severe genetic disease that is inherited in an autosomal recessive manner, affecting the short arm of chromosome 7 of the CFTR gene, causing alterations in the transmembrane conductance regulator protein (CFTR), This causes dysfunctional transport of chloride, sodium and bicarbonate leading to the generation of thick and viscous secretions in the lungs, pancreas, liver, intestine and reproductive tract while in the sweat glands there will be increased salt content.  The clinical manifestations depend on the degree of mutation present in the gene, and may appear within a few months of birth or may even take decades. Life expectancy in patients with cystic fibrosis in Ecuador is 9.5 years and is mainly related to the quality of treatment and especially with early diagnosis since lung damage begins at birth.  A retrospective study was made with various databases and keywords related to Cystic Fibrosis and it was found that the main system affected is the respiratory system, its main clinical manifestations, persistent productive cough, hyperinflation of lung fields and airway obstruction, as the disease progresses and exposure to infections, there will be a progressive deterioration of the lung that will manifest itself in acute exacerbations of cough, tachypnea, dyspnea and increased sputum production. With respect to the digestive system, two thirds of CF patients have pancreatic insufficiency and most have signs of poor or deficient fat absorption, including symptoms and signs such as steatorrhea, growth retardation or weight gain, and in infants edema, hypoproteinemia, electrolyte loss and anemia may occur.
Pengaruh Sarana dan Prasarana Sekolah Terhadap Motivasi Belajar Siswa Kelas XI TKR SMK Negeri 2 Siatas Barita Kabupaten Tapanuli Utara Tahun Ajaran 2024
Authors: Simanjuntak Nigora Kislew , Lumban Tobing Lasmaria , Tambunan Abai Manupak
Published: July 2024

Penelitian ini bertujuan untuk mengetahui adanya pengaruh yang positif dan signifikan Sarana dan Prasarana Sekolah terhadap Motivasi Belajar Siswa Kelas XI TKR SMK Negeri 2 Siatas Barita Tahun Ajaran 2024. Penelitian ini menggunakan pendekatan kuantitatif dengan populasi seluruh kelas XI TKR SMK Negeri 2 Siatas Barita berjumlah 101 orang dengan sampel berjumlah 33 orang. Data dikumpulkan dengan angket sebanyak 30 item yang disusun berdasarkan indikator variabel sesuai teori. Uji coba angket dilakukan kepada 30 orang di tempat yang sama yaitu kelas XI TKR di luar sampel penelitian, telah diuji validitas dan reliabilitasnya. Hasil analisis data menunjukkan bahwa terdapat pengaruh yang positif dan signifikan Sarana dan Prasarana Sekolah terhadap Motivasi Belajar Siswa Kelas XI TKR SMK Negeri 2 Siatas Barita Tahun Ajaran 2024 yang dibuktikan dengan a). Uji hubungan yang positif diperoleh nilai rhitung = 0,610 > rtabel = 0,344 dengan demikian diketahui bahwa terdapat hubungan yang positif antara variabel X dan variabel Y. b). Uji hubungan yang signifikan diperoleh nilai thitung = 4,284 > ttabel = 2,042. c) Uji koefisien determinasi r2 =37,20%. d) Uji persamaan regresi sederhana diperoleh ????̂ = 35,502 + 0,315X. e) Uji signifikan pengaruh menggunakan uji f diperoleh fhitung > ftabel yaitu 18,349>1,62. Dengan demikian Ha diterima dan Ho ditolak.
HUBUNGAN TINGGI LOMPATAN TERHADAP KETEPATAN SHOOTING DALAM PERMAINAN BOLA BASKET PADA SISWA SMPN 1 DOMPU
Authors: Linda Susila  , Taufiq Hidayat  , Rizky Aris Munandar
Published: July 2024

Penelitian ini bertujuan untuk  mengetahui hubungan tinggi lompatan dengan prediksi terhadap ketepatan shooting dalam permainan bola basket. Penelitian ini, menggunakan metode penelitian kuantitatif dengan pendekatan korelasional, sehingga dapat disusun dalam rancangan sebagai berikut, X: tinggi lompatan sedangkan Y: ketepatan shooting. Untuk pengambilan sampel tersebut, menggunakan teknik “strata sampling”  dengan membagi seluruh populasi menjadi kelompok yang homogen sehingga pengambilan sampelnya secara acak bertingkat proporsional melibatkan pengambilan sampel acak dari kelompok bertingkat. Teknik pengumpulan data yang digunakan adalah tes perbuatan. Analisa data menggunakan rumus product moment. Berdasarkan hasil data yang diperoleh dari analisis menunjukkan bahwa “ada hubungan tinggi lompatan terhadap ketepatan shooting dalam permainan bola basket pada siswa SMPN 1 Dompu. Dengan nilai yang diperoleh yaitu Rhitung sebesar  = 0,642 dan Rtabel menggunakan taraf signifikan 5%, Sedangkan  N = 28 diperoleh nilai Rtabel sebesar = 0,374. Maka telihat dari nilai Rtabel menunjukan  terdapat hubungan yang sangat kuat dari tinggi lompatan terhadap ketepatan shooting dalam permainan bola basket
PENGARUH LATIHAN KELINCAHAN TERHADAP KETERAMPILAN DRIBBLING BOLA DALAM PERMAINAN SEPAK BOLA
Authors: Iman Zulfikar  , Taufiq Hidayat  , Rizky Aris Munandar
Published: July 2024

Penelitian ini bertujuan untuk melihat apakah ada pengaruh Latihan kelincahan terhadap keterampilan driblling bola dalam permainan sepak bola pada siswa SMAN 1 Dompu. Adapun jenis penelitian ini adalah penelitian kuantitaf dan metode yang digunakan metode One group pretest-posttest Design. Sampel pada penelitian ini adalah 20 0rang siswa. Instrumen yang diberikan merupakan hasil evaluasi dan pengumpulan data yang diperoleh sebagai acuan untuk memberikan metode Latihan terhadap hasil pretest dan posttest. Teknik pengambilan sampelnya menggunakan Purposive sampling, Berdasarkan hasil hitungan data maka dapat disimpulkan ada pengaruh Latihan kelincahan terhadap keterampilan menggiring bola. Hal ini dibuktikan dengan nilai Thitung 6,160 sedangkan Ttabel1.734 (dk) dengan dk = n-2= 18 dan taraf  signifikan 0,05 atau 5%, maka T tabel= 1,734 (uji satu pihak dengan interpolansi), berarti terdapat perbedaan yang signifikan antara siswa yang menggiring bola dengan teknik zig-zag dengan demikian maka Ho ditolak dan Ha diterima, yang berarti ada pengaruh yang nyata (signifikan) antara variabel (X) terhadap Variabel (Y). Ttabel yang dimaksud adalah untuk menghitung nilai variabel X yaitu latihan kelincahan, sedangkan thitung ialah untuk menghitung nilai variabel Y yaitu keterampilan menggiring bola pada siswa kelas XI IPA 2 SMAN 1 Dompu.
PERBANDINGAN KETEPATAN SASARAN ANTARA SERVICE ATAS DAN SERVICE BAWAH DALAM PERMAINAN VOLLY BALL PADA SISWA SMPN 4 DOMPU
Authors: Linda Susila  , Taufiq Hidayat  , Muhlas Ade Putra
Published: July 2024

Permainan volley ball merupakan permainan yang membutuhkan teknik dan kemampuan dasar dalam bermain, lebih khususnya kemampuan melakukan service, baik service atas maupun service bawah. Dalam hal ini teknik-teknik dasar yang dimiliki ketika melakukan  Service, baik service atas maupun service bawah merupakan hal yang menopang kelincahan dalam bermain. Masalah yang dijawab ini adalah apakah ada perbedaan ketepatan sasaran antara service atas dan service bawah dalam permainan volley ball pada siswa putra kelas VIII SMPN 4 Dompu. Dan tujuan dari penelitiannya adalah untuk mengetahui teknik servis yang mempunyai ketepatan yang baik dan efektif, antara service atas dengan service bawah dan untuk membandingkan ketepatan antara service atas dengan service bawah yang lebih signifikan. Jenis penelitian yang digunakan merupakan penelitian non eksperimen dengan pendekatan deskriptif kuantitatif. Untuk pengambilan sampel menggunakan simple random sampling. Berdasarkan hasil perhitungan analisis data diperoleh dari data tes T-hitung yaitu 19,9 sedangkan T-tabel dengan taraf signifikan 0,05 atau 5% maka T-tabel nilainya sebesar 2,12. Maka terlihat dari nilai T-tabel menunjukan  terdapat perbedaan yang signifikan antara ketepatan sasaran service atas dengan service bawah dalam permainan volley ball pada siswa putra kelas VIII SMP Negeri 4 Dompu. Maka hipotesis yand diajukan menyatakan di terima
Las escuelas democráticas y los retos para la práctica y la teoría educativas
Authors: Dongo Montoya Adrian Oscar
Published: July 2024

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Las escuelas democráticas nacieron y se desarrollaron por compromiso y coherencia con los principios y los valores democráticos de la modernidad y las luchas civilizatorias de los pueblos. En los últimos tiempos, se han desarrollado y organizado en un movimiento global; sin embargo, su aceptación y expansión es todavía un fenómeno restringido y periférico en relación con el modelo tradicional de enseñanza centrado en la jerarquía y la transmisión. Un análisis histórico de las experiencias educativas democráticas muestra que se basan en principios trabajados por sus pioneros y en la investigación científica contemporánea. En este artículo analizaremos la génesis y las experiencias pedagógicas libertarias, las dificultades y los desafíos teóricos que plantean para su avance, el pensamiento educativo y la formación de educadores.
The Role of The National Land Agency (BPN) In Resolving Land Disputes In Indonesia
Authors: Pasamai Syamsuddin , Salle Salle
Published: July 2024

Land disputes are one of the complex and frequent agrarian problems in Indonesia. Therefore, systematic and targeted efforts are needed to resolve land disputes in Indonesia. The National Land Agency (BPN) as a government agency tasked with managing land has an important role in resolving land disputes. This research aims to examine the role of BPN in resolving land disputes in Indonesia. The research method used in this study is a qualitative method. The data collection technique in this research is literature study. The data that has been collected is then analyzed in three stages, namely data reduction, data presentation and drawing conclusions. The research results show that BPN has a central role in resolving land disputes in Indonesia. As an institution responsible for land administration and management, BPN plays a role in facilitating legal and administrative processes related to ownership, utilization and resolution of land disputes. BPN is tasked with providing legal certainty regarding land status, verifying ownership claims, and providing land certificates to the legal owners. Apart from that, BPN also plays a role in mediating and resolving conflicts between parties involved in land disputes, whether between individuals, traditional communities, or private parties. BPN's role is not only limited to administrative aspects, but also includes efforts to create fair and sustainable solutions, taking into account various social, economic and environmental aspects.
CDA Cancer Screening Strategies For Anxiety Health Checkup Cancer Screening
Authors: Gracia Anne
Published: July 2024

The purpose of this study was to find out how anxiety affects cancer detection and how early detection efforts are carried out in conjunction with screening. The mixed methods study was conducted on 1002 random subjects. In addition, qualitative research models were conducted on laboratory specialists, health examiners and oncologists on CDA screening methods. This method does not cause reports of disease, but shows that there is a good tendency to cancer. The results of the study were processed using SEM PLS analysis using SmartPLS and expert opinion analysis using Facets. The expert source's opinion (expert decision) on the transfer of detection perception to screening using the CDA method is considered feasible and constructive. Reliability is calculated by the FACETS Program as a measure of sample variance, therefore, low values among a sample of raters indicate that the raters in the assessment are relatively homogeneous, with heterogeneous raters. There are no problems with convergent validity on the tested models; the AVE value of each construct exceeds 0.5, which means that the construct has good reliability. The results of PLS bootstrapping calculations showed a significant direct relationship between variables, suggesting a link between anxiety and health screenings.CDA screening can be an option to overcome health screening anxiety because it informs test results with a tendency between healthy findings and the likelihood of cancer appearing, rather than active cancer cells.
Non-Formal Education Policy in Indonesia
Authors: Wiharjo Suyadi Murdi , Wulandari Dian
Published: July 2024

This research aims to identify non-formal education policies in Indonesia. This study uses a qualitative method. The research approach uses literature studies and a descriptive approach. Data was obtained from policy documents and reference journals. The research results show that at the macro level, the non-formal education policy is the 1945 Constitution, Law no. 20 of 2003 concerning the National Education System and Regional Regulations. Then, at the meso level, there is Minister of Education and Culture Regulation Number 49 of 2007 concerning Education Management Standards by Non-formal Education Units, Regulation of the Governor of the Special Capital Region of Jakarta Province Number 67 of 2017 concerning the Implementation and Management of Non-formal Education, several Regent Regulations and Mayor Regulations. In the end, the policy at the micro level is the Mayor of Semarang City Regulation Number 18 of 2023 concerning Technical Guidelines for Providing Honorariums to Non-formal and Non-formal Religious Educators, Corpse Care Officers and Prosperity Officers in Places of Worship. The government, regional heads, and legislators need to pay attention to non-formal education policies at the macro, meso, and micro levels so that the contribution of non-formal education is more optimal in creating superior and competitive human resources.