bluuebunny/crossref_metadata_2025 huggingface dataset:
Repurposing Insecticides for Mosquito Control: Evaluating Spiromesifen, a Lipid Synthesis Inhibitor against Aedes aegypti (L.)
Authors: Cerda-Apresa Daniela , Gutierrez-Rodriguez Selene M. , Davila-Barboza Jesus A. , Lopez-Monroy Beatriz , Rodriguez-Sanchez Iram P. , Saavedra-Rodriguez Karla L. , Flores Adriana E.
Published: August 2024

The growing resistance of Aedes aegypti (L.) to conventional insecticides presents a major challenge in arbovirus control, necessitating the exploration of alternative insecticidal chemistries. Spiromesifen, derived from spirocyclic tetronic acids, is widely used against agricultural pests and is crucial in resistance management due to its unique lipid synthesis inhibition. This study evaluates the insecticidal activity of spiromesifen against temephos-resistant Ae. aegypti populations, focusing on larval body weight, volume, biochemical composition, and adult female reproductive potential. Spiromesifen demonstrated effective larvicidal activity, significantly reducing adult emergence. Resistance to spiromesifen was not observed, with resistance ratios (RR50, RR90) ranging from 0.36- to 3.31-fold. Larvae exposed to LC50 showed significant reductions in body weight and volume, and reduced carbohydrate, lipid, and protein contents. Enhanced catalase activity and malondialdehyde levels indicated increased oxidative stress and lipid peroxidation, highlighting its effects on lipid metabolism. Spiromesifen also exhibited sterilizing effects, significantly reducing fecundity and fertility in adult females, thereby impacting Ae. aegypti reproductive capacity. These findings highlight the potential of spiromesifen as a component of integrated vector management strategies, especially in regions with prevalent insecticide resistance in Ae. aegypti, serving as an effective larvicide and impacting adult reproductive outcomes.
CRL4-DCAF1 Ubiquitin Ligase Dependent Functions of HIV Viral Protein R and Viral Protein X
Authors: Dobransky Ashley , Root Mary , Hafner Nicholas , Marcum Matty , Sharifi H. John
Published: August 2024

The Human Immunodeficiency Virus (HIV) encodes several proteins that contort the host cell environment to promote viral replication and spread. This is often accomplished through the hijacking of cellular ubiquitin ligases. These reprogrammed complexes initiate or enhance the ubiquitination of cellular proteins that may otherwise act to restrain viral replication. Ubiquitination of target proteins may alter protein function or initiate proteasome-dependent destruction. HIV Viral Protein R (Vpr) and the related HIV-2 Viral Protein X (Vpx), engage the CRL4-DCAF1 ubiquitin ligase complex to target numerous cellular proteins. In this review we describe the CRL4-DCAF1 ubiquitin ligase complex and its interactions with HIV Vpr and Vpx. We additionally summarize the cellular proteins targeted by this association as well as the observed or hypothesized impact on HIV.
Influenza Vaccination Coverage in Children: How Has COVID-19 Influenced It? A Review of Five Seasons (2018–2023) in Central Catalonia, Spain
Authors: Burgaya-Subirana Sílvia , Balaguer Mònica , Miró Catalina Queralt , Sola Laia , Ruiz-Comellas Anna
Published: August 2024

Influenza vaccination is the main method of preventing influenza. Vaccination is recommended for certain individuals with diseases that could cause complications in the case of flu infection. The objective of this retrospective observational study was to examine influenza vaccination coverage in patients with risk factors, to describe the characteristics of those vaccinated and to study the influence of COVID-19. The study population was children under 14 years old with risk factors between 2018/19 and 2022/23 in Central Catalonia, sourced through the electronic database of the Catalan Institute of Health. The association of influenza vaccination data with sociodemographic data and risk factors was performed by bivariate and multivariate analysis. A total of 13,137 children were studied. Of those, 4623 had received the influenza vaccine in at least one season. The average influenza vaccination rate was 28.8%. The statistically significant factors associated with vaccination were age and having certain risk factors: asthma, diabetes, haemoglobinopathies and clotting disorders. In all seasons, the immigrant population was vaccinated more than the native population p < 0.05, except for the COVID-19 season (2020/21), where no differences were observed. Of those vaccinated, 7.1% had been vaccinated for 5 consecutive years. Influenza vaccination coverage in the paediatric age group was low. Vaccination promotion measures must be implemented. COVID-19 meant an increase in vaccination of the native population to the same level as that of the immigrant population.
DNA Vaccines Encoding HTNV GP-Derived Th Epitopes Benefited from a LAMP-Targeting Strategy and Established Cellular Immunoprotection
Authors: Jiang Dongbo , Zhang Junqi , Shen Wenyang , Sun Yubo , Wang Zhenjie , Wang Jiawei , Zhang Jinpeng , Zhang Guanwen , Zhang Gefei , Wang Yueyue , Cai Sirui , Zhang Jiaxing , Wang Yongkai , Liu Ruibo , Bai Tianyuan , Sun Yuanjie , Yang Shuya , Ma Zilu , Li Zhikui , Li Jijin , Ma Chenjin , Cheng Linfeng , Sun Baozeng , Yang Kun
Published: August 2024

Vaccines has long been the focus of antiviral immunotherapy research. Viral epitopes are thought to be useful biomarkers for immunotherapy (both antibody-based and cellular). In this study, we designed a novel vaccine molecule, the Hantaan virus (HTNV) glycoprotein (GP) tandem Th epitope molecule (named the Gnc molecule), in silico. Subsequently, computer analysis was used to conduct a comprehensive and in-depth study of the various properties of the molecule and its effects as a vaccine molecule in the body. The Gnc molecule was designed for DNA vaccines and optimized with a lysosomal-targeting membrane protein (LAMP) strategy. The effects of GP-derived Th epitopes and multiepitope vaccines were initially verified in animals. Our research has resulted in the design of two vaccines based on effective antiviral immune targets. The effectiveness of molecular therapies has also been preliminarily demonstrated in silico and in laboratory animals, which lays a foundation for the application of a vaccines strategy in the field of antivirals.
Analysis of the Spatiotemporal Variability of Hydrological Drought Regimes in the Lowland Rivers of Kazakhstan
Authors: Birimbayeva Lyazzat , Makhmudova Lyazzat , Alimkulov Sayat , Tursunova Aisulu , Mussina Ainur , Tigkas Dimitris , Beksultanova Zhansaya , Rodrigo-Clavero María-Elena , Rodrigo-Ilarri Javier
Published: August 2024

Hydrological droughts occur as a result of various hydrometeorological conditions, such as precipitation deficits, reduced snow cover, and high evapotranspiration. Droughts caused by precipitation deficits and occurring during warm seasons are usually longer in duration. This important observation raises the question that climate change associated with global warming may increase drought conditions. Consequently, it is important to understand changes in the processes leading to dry periods in order to predict potential changes in the future. This study is a scientific analysis of the impact of climate change on drought conditions in the Zhaiyk–Caspian, Tobyl–Torgai, Yesil, and Nura–Sarysu water management basins using the standardized precipitation index (SPI) and streamflow drought index (SDI). The analysis methods include the collection of hydrometeorological data for the entire observation period up to and including 2021 and the calculation of drought indices to assess their intensity and duration. The results of this study indicate an increase in the intensity and frequency of drought periods in the areas under consideration, which is associated with changes in climatic conditions. The identified trends have serious implications for agriculture, ecological balance, and water resources. The conclusions of this scientific study can be useful for the development of climate change adaptation strategies and the sustainable management of natural resources in the regions under consideration.
Identification of the Runoff Evolutions and Driving Forces during the Dry Season in the Xijiang River Basin
Authors: Wang Fei , Men Ruyi , Yan Shaofeng , Wang Zipeng , Lai Hexin , Feng Kai , Gao Shikai , Li Yanbin , Guo Wenxian , Tian Qingqing
Published: August 2024

During the dry season, river flow gradually diminishes, and surface water flow dries up. Therefore, the investigation of runoff during the dry season is of great practical significance for rational water allocation and water resource management. Based on hydrological station data from the Xijiang River Basin (XRB) from 1961 to 2020, this study examines the trend and periodic characteristics of dry-season runoff, identifies fluctuation and variability in dry-season runoff, and investigates the main circulation factor combinations influencing dynamic changes in dry-season runoff. The results indicate the following: (1) the characteristics of dry-season runoff variations are basically consistent across sub-basins in the XRB during the study period, with the minimum (21.96 × 108 m3) and maximum (54.67 × 108 m3) average monthly runoff occurring in February and October, respectively; (2) interannual-scale dry-season runoff exhibits periodicity of 3.53 years and 7.5 years; (3) using the Bayesian estimator of abrupt seasonal and trend change algorithm (BEAST), a seasonal abrupt point with a probability of 20.5% occurs in 1983, and the confidence interval for this abrupt point is from 1980 to 1986; (4) based on the cross wavelet approach, solar sunspots are identified as the primary circulation factor contributing to dry-season runoff in the XRB, exhibiting a significant 8–14 years resonance cycle of negative correlation with runoff during the high-energy phase from 1972 to 2006. These findings offer a new perspective on understanding the evolution of dry-season runoff and circulation factor variations, which are crucial for accurate prediction, early warning, and rational allocation of water resources during the dry season.
Research on the Relationship between Eukaryotic Phytoplankton Community Structure and Key Physiochemical Properties of Water in the Western Half of the Chaohu Lake Using High-Throughput Sequencing
Authors: Zhao Bingbing , Peng Wei , Zhu Xinhao , Zhang Hua , Zhuang Xingmei , Wang Jinhua , Xi Shanshan , Luo Tao
Published: August 2024

Eukaryotic phytoplankton play a major role in the circulation of material and energy in a lake’s ecosystem. The acquisition of information on the eukaryotic phytoplankton community is extremely significant for handling and regulating the ecosystems of lakes. In this study, samples were collected from the western half of Chaohu Lake in the summer and winter periods. Analyses revealed that the eukaryotic phytoplankton in this region comprised 70 genera, 34 orders, and 7 phyla. There were 61 genera, 29 orders, and 7 phyla in summer, and 25 genera, 14 orders, and 5 phyla in winter. The dominant genus was Chlamydomonas of Chlorophyta in summer. In contrast, the dominant genus was Mychonastes of Chlorophyta in winter. The diversity index analysis revealed that the eukaryotic phytoplankton community exhibited greater fluctuation in the summer than in the winter. Moreover, analysis of the physiochemical properties of the water samples showed considerable spatial and temporal differences in the water quality. This paper focusses primarily on analysing the influence of the physiochemical properties of water on the eukaryotic phytoplankton community. In particular, the effects of the major physicochemical properties of water on the community evolution of eukaryotic phytoplankton classes were evaluated using the redundancy analysis method. The findings demonstrated that total phosphorus (TP), PO4−-P, NH4+-N, and total nitrogen (TN) were the primary influencing factors in summer, whereas NO3−-N, DO, and water temperature (WT) were the major influencing factors in winter. Subsequently, the Mantel test revealed that the phylum level of the eukaryotic phytoplankton community was significantly correlated with WT, DO, NH4+-N, TN, TP, and Chlorophyll a. Variance partitioning analysis indicated that seasonal factors accounted for a large proportion of the variation in the eukaryotic phytoplankton community, reaching 48.4%. Subsequently, co-occurrence network analysis demonstrated that most families of eukaryotic phytoplankton were facilitated mutually, with the proportion of promotion being 94.1%. This study provides insight into the crucial factors that influence the phytoplankton communities and a reasonable control direction for the positive evolution of the eukaryotic phytoplankton community in the western half of Chaohu Lake.
Multi-Stage Burst Localization Based on Spatio-Temporal Information Analysis for District Metered Areas in Water Distribution Networks
Authors: Zhang Xiangqiu , Fang Yongjun , Zhou Xinhong , Shao Yu , Yu Tingchao
Published: August 2024

Burst events in Water Distribution Networks (WDNs) pose a significant threat to the safety of water supply, leading people to focus on efficient methods for burst localization and prompt repair. This paper proposes a multi-stage burst localization method, which includes preliminary region determination and precise localization analysis. Based on the hydraulic model and spatio-temporal information, the effective sensor sequences and monitoring areas of the nodes are determined. In the first stage, the preliminary burst region is determined based on the monitoring region of sensors and the alarm sensors. In the second stage, localization metrics are used to analyze the dissimilarity degree between burst data from the hydraulic model and the monitoring data from the effective sensors at each node. This analysis helps identify candidate burst nodes and determine their localization priorities. The localization model is tested on the C-Town network to obtain comparative results. The method effectively reduces the burst region, minimizes the search region, and significantly improves the efficiency of burst localization. For precise localization, it accurately localizes the burst event by prioritizing the possibilities of the burst location.
Study on Demulsification Pre-Treatment of Emulsified Wastewater
Authors: Tian Yue , Li Haixia , Wu Wenyu , Wu Ying , Zhou Baochang
Published: August 2024

In this paper, the flocculation effect of single flocculants and compound flocculants on emulsified wastewater under different conditions was studied. The effect of flocculant type, dose, settling time and composite ratio of flocculant on the treatment of emulsified wastewater were investigated through single-factor condition tests, and then the optimal conditions of flocculants for treating emulsified wastewater were obtained. The results showed that the single inorganic flocculant could break the stable state of the emulsion when the pH was adjusted to 7 and formed tiny flocs, but it took a long time to settle down. The single organic flocculant had no flocculation effect. The inorganic–organic composite flocculants could effectively solve the problem of emulsion breaking and flocculation, and could form large flocs and alum flower formations at the same time, with mud and water effectively separated. The best conditions for the composite flocculants were as follows: under the condition of room temperature and pH 7, the dose of PFC was 2250 mg/L and APAM was 5 mg, the homogeneous stirring time was 10 min, and the settling time was 0.5 h. The removal rate of COD and turbidity reached 84.75% and 99.86%. The study could provide a new treatment idea and method for the pretreatment of stabilized high-turbidity wastewater.
A Comprehensive Inventory, Characterization, and Analysis of Rock Glaciers in the Jhelum Basin, Kashmir Himalaya, Using High-Resolution Google Earth Data
Authors: Abdullah Tariq , Romshoo Shakil Ahmad
Published: August 2024

Rock glaciers are crucial freshwater resources, yet detailed knowledge about their distribution, characteristics, and dynamics in the Himalayan region is scarce. This study presents a comprehensive rock glacier inventory of the Jhelum basin, Kashmir Himalaya, India, using high-resolution Google Earth data. We identified 240 rock glaciers covering an area of 41.24 ± 2.2 km2, with ~76% classified as active, ~20% inactive, and 3.7% relict. The average areas and lengths of these rock glacier types were 0.19 km2, 0.06 km2, and 0.29 km2, and 699 m, 426 m, and 952 m, respectively. Most rock glaciers (~90%) were oriented northwards (N, NE, NW), while only 5% faced southwards (S, SE, SW). The lower limit of permafrost in the Jhelum basin is about 3316 m asl. Furthermore, we estimated the ice storage of rock glaciers in the Jhelum basin at 0.80 ± 0.13 km3, equivalent to 0.72 ± 0.12 km3 of water volume. This study enhances our understanding of permafrost distribution and the characteristics and dynamics in the basin. Given their greater resilience to climate change compared to clean glaciers, the hydrological significance of rock glaciers is expected to increase under projected climate change scenarios. This study highlights their importance as a vital water resource amidst the accelerated recession of clean glaciers.
Human Activities Impacts on Runoff and Ecological Flow in the Huangshui River of the Yellow River Basin, China
Authors: Liu Lanxin , Fan Lijuan , Hu Jing , Li Chunhui
Published: August 2024

This study analyzed 61 years of hydrological data from the Minhe and Xiangtang Hydrological Stations (1956–2016) to examine hydrological changes and ecological flow assurance rates in the Huangshui River Basin, China. Using the Mann–Kendall trend test, IHA/RVA method, and ecological flow calculation methods, the study revealed the following results: (1) After 1994, increased human activity in the Datong River led to a measured runoff decrease compared to natural runoff. Although human activities in the Huangshui River’s main stream were present before 1972, after 1972, these activities intensified, resulting in a more pronounced decrease in the measured runoff. (2) Ecological flow analysis indicated that the main stream of the Huangshui River and the Datong River have ecological flow assurance rates of 100% for all but a few months, where the rates are 98%. The water volume is sufficiently abundant to meet ecological water demands.
Analysis and Suppression of Spoke-Type Permanent Magnet Machines Cogging Torque with Different Conditions for Electric Vehicles
Authors: Huang Jinlin , Wang Chen
Published: August 2024

Spoke-type permanent magnet (STPM) machines have high power density and low cost due to flux concentrated effect and high air-gap flux density, but they can cause high cogging torque and torque ripple. To reduce the cogging torque, the analytical model considering a rotor slot is established and compared with the finite element mothed (FEM). Then, the cogging torque production mechanism is revealed and analyzed under different conditions, which provides direction to optimize the cogging torque STPM machines. The harmonic content of cogging torque under different conditions is obtained based on the freezing permeability (FP) method. It is found that the fundamental waves mainly generate the cogging torque under a no-load condition, and it is mainly generated by the second harmonics under an on-load condition. In addition, the optimization method is introduced and researched, including rotor slot width, uneven rotor core, and so on. Finally, a 50 kW STPM machine prototype is manufactured and tested to verify the accuracy and efficiency of the analysis method.
Regulation of cell fate by cell imprinting approach in vitro
Authors: Hasannejad Farkhonde , Montazeri Leila , Mano João F , Bonakdar Shahin , Fazilat Ahmad ‎
Published: August 2024

Cell culture-based technologies are widely utilized in various domains such as drug evaluation, toxicity assessment, vaccine and biopharmaceutical development, reproductive technology, and regenerative medicine. It has been demonstrated that pre-adsorption of extracellular matrix (ECM) proteins including collagen, laminin and fibronectin provide more degrees of support for cell adhesion. The purpose of cell imprinting is to imitate the natural topography of cell membranes by gels or polymers to create a reliable environment for the regulation of cell function. The results of recent studies show that cell imprinting is a tool to guide the behavior of cultured cells by controlling their adhesive interactions with surfaces. Therefore, in this review we aim to compare different cell cultures with the imprinting method and discuss different cell imprinting applications in regenerative medicine, personalized medicine, disease modeling, and cell therapy.
Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance
Authors: Eskandani Ramin , Zibaii Mohammad Ismail
Published: August 2024

Introduction: Radiofrequency electromagnetic radiation (RF-EMR) and extremely low-frequency electromagnetic fields (ELF-EMF) have emerged as noteworthy sources of environmental pollution in the contemporary era. The potential biological impacts of RF-EMR and ELF-EMF exposure on human organs, particularly the central nervous system (CNS), have garnered considerable attention in numerous research studies. Methods: This article presents a comprehensive yet summarized review of the research on the explicit/implicit effects of RF-EMR and ELF-EMF exposure on CNS performance. Results: Exposure to RF-EMR can potentially exert adverse effects on the performance of CNS by inducing changes in the permeability of the blood-brain barrier (BBB), neurotransmitter levels, calcium channel regulation, myelin protein structure, the antioxidant defense system, and metabolic processes. However, it is noteworthy that certain reports have suggested that RF-EMR exposure may confer cognitive benefits for various conditions and disorders. ELF-EMF exposure has been associated with the enhancement of CNS performance, marked by improved memory retention, enhanced learning ability, and potential mitigation of neurodegenerative diseases. Nevertheless, it is essential to acknowledge that ELF-EMF exposure has also been linked to the induction of anxiety states, oxidative stress, and alterations in hormonal regulation. Moreover, ELF-EMR exposure alters hippocampal function, notch signaling pathways, the antioxidant defense system, and synaptic activities. Conclusion: The RF-EMR and ELF-EMF exposures exhibit both beneficial and adverse effects. Nevertheless, the precise conditions and circumstances under which detrimental or beneficial effects manifest (either individually or simultaneously) remain uncertain.
Microfluidics as a promising technology for personalized medicine
Authors: Oushyani Roudsari Zahra , Esmaeili Zahra , Nasirzadeh Nafiseh , Heidari Keshel Saeed , Sefat Farshid , Bakhtyari Hassan , Nadri Samad
Published: August 2024

Introduction: Due to the recent advances in biomedicine and the increasing understanding of the molecular mechanism of diseases, healthcare approaches have tended towards preventive and personalized medicine. Consequently, in recent decades, the utilization of interdisciplinary technologies such as microfluidic systems had a significant increase to provide more accurate high throughput diagnostic/therapeutic methods. Methods: In this article, we will review a summary of innovations in microfluidic technologies toward improving personalized biomolecular diagnostics, drug screening, and therapeutic strategies. Results: Microfluidic systems by providing a controllable space for fluid flow, three-dimensional growth of cells, and miniaturization of molecular experiments are useful tools in the field of personalization of health and treatment. These conditions have enabled the potential to carry out studies like; disease modeling, drug screening, and improving the accuracy of diagnostic methods. Conclusion: Microfluidic devices have become promising point-of-care (POC) and personalized medicine instruments due to their ability to perform diagnostic tests with small sample volumes, cost reduction, high resolution, and automation.
A systematic review on the use of phytotherapy in managing clinical depression
Authors: Fazilat Sutude , Tahmasbi Fateme , Mirzaei Mohammad Reza , Sanaie Sarvin , Yousefi Zahra , Asnaashari Solmaz , Yaqoubi Shadi , Banagozar Mohammadi Ahad , Araj-khodaei Mostafa
Published: August 2024

Introduction: The use of medicinal plants in the management of depression, also known as phytotherapy or herbal medicine for depression, is an area of growing interest in the field of mental health and complementary medicine. Methods: This study used a systematic assessment of pertinent literature to assess the effectiveness of medicinal herbs in treating mild to severe depression. A comprehensive literature search was conducted to identify randomized controlled trials (RCTs) that reported data on the intervention, control group, adverse events, outcome measurements, and main findings. A summary and analysis were done on the included research data. Results: We included 23 RCTs investigating the efficacy of herbal medicines, including Crocus sativus, Lavandula angustifolia, Melissa officinalis, and Echium amoenum, in treating depression. In general, saffron showed encouraging outcomes when used to treat mild to severe depression. With no discernible variations in the reported adverse effects, it proved to be equally efficacious as well-known antidepressants like imipramine and fluoxetine. However, it is noteworthy that not all trials yielded favorable results. Conclusion: More investigation is required to fully understand the mechanisms of action, ideal dosage schedules, long-term effects, and relative efficacy of medicinal plants in depressive treatment.
Political Prioritization of Access to Medicines and Right to Health: Need for an Effective Global Health Governance Through Global Health Diplomacy Comment on "More Pain, More Gain! The Delivery of COVID-19 Vaccines and the Pharmaceutical Industry’s Role in Widening the Access Gap"
Authors: Kumar Chattu Vijay , Pushkaran Anjali , Narayanan Prakash
Published: August 2024

Borges and colleagues’ article entitled "More Pain, More Gain! The Delivery of COVID-19 Vaccines and the Pharmaceutical Industry’s Role in Widening the Access Gap," analyzes the role of pharmaceutical companies in providing equitable access to COVID-19 vaccines. They concluded that with the failure of COVID-19 Vaccine Global Access (COVAX), the health gaps have widened due to the profit-driven pharmaceutical sector. In this commentary, we highlight the role of COVAX and its attempt to bridge some access gaps since its inception and the need for reforms in policy-making and global health governance. The commentary highlights the role of global health diplomacy in promoting equity and negotiating the Trade-Related Aspects of Intellectual Property Rights (TRIPS) waiver for COVID-19 vaccines at the World Trade Organization (WTO) thereby promoting global solidarity, global partnerships, access to medicine and health products, and the right to health. We conclude that political prioritization is the key to balance the impact of profit-driven pharma industry and addressing the needs of low- and middle-income countries (LMICs).
A Multifaceted Approach to Health Crisis in the Philippines Comment on "Experiences and Implications of the First Wave of the COVID-19 Emergency in Italy: A Social Science Perspective"
Authors: Cordero Jr. Dalmacito A.
Published: August 2024

The COVID-19 pandemic changed the landscape of every country’s healthcare system. May it be a developed nation like Italy or a developing one, like Philippines, it has seriously impacted the different aspects of people’s everyday living. While the epidemiological/pharmacological interventions is the top priority to battle the health crisis, considering the social science perspective in crafting any health policy is a must to develop holistic, relevant, and effective programs for policy-makers. This is not to underestimate the effectiveness of the former but it simply signifies the essential support of the latter for a higher success rate since it is a multifaceted approach. It is important to note that a human is not only composed of physicality, but all the other aspects that are connected to one another, including social, political, and spiritual ones.
On the Tymoczko Codes for Standard Young Tableaux
Authors: Olasupo Felemu , Adeyemo Praise
Published: August 2024

Given a partition $\lambda$ of integer $n>0$, there exists a diagram (called Young diagram $\mathcal{ Y}_{\lambda}$) associated with $\lambda$. The filling of such diagram from $[n]$ such that the entries increase from top to bottom and from left to right is called the standard Young tableaux ($ SYT$) of shape $\lambda$. In this paper, we associate an invariant with each standard Young tableau of shape $\lambda$, and provide some combinatorial interpretations of these invariants.
ANALYSIS OF MULTI-FREQUENCY SEISMIC DATA FOR THE STRATIGRAPHIC DRILLING (THE DE LONG RISE, EAST SIBERIAN SEA)
Authors: Хлебникова О.А. , Замотина З.С. , Понимаскин А.А. , Терёхина Я.Е. , Токарев М.Ю. , Никишин А.М.
Published: August 2024

Целью стратиграфического бурения при освоении нефтегазового потенциала осадочных бассейнов является составление максимально достоверной модели геологического строения изучаемого региона посредством получения керна из глубоких целевых горизонтов. Строение осадочных бассейнов Российской Арктики позволяет использовать малоглубинные скважины для доизучения глубинного строения. Важным этапом в проектировании буровых работ является выбор оптимальной точки заложения скважины, который в значительной степени основывается на анализе сейсмических материалов. Традиционно изучение глубокозалегающих целевых горизонтов в рамках поисково-оценочного этапа геолого-разведочных работ проводится по данным 2D-сейсморазведки стандартного разрешения (2D СР). Для целей малоглубинного стратиграфического бурения, которое проводится в верхней части разреза (ВЧР), стандартные подходы к обработке данных 2D СР не оптимальны, разработаны методы специализированной обработки материалов 2D СР, способствующие улучшению вертикальной и горизонтальной разрешающей способности в ВЧР. В работе представлены результаты детального изучения строения ВЧР для выбора точки заложения малоглубинной стратиграфической скважины во внешнем секторе Восточно-Арктического шельфа РФ. Проведен анализ особенностей строения геологического разреза в районе поднятия Де-Лонга по данным 2D СР после специализированной обработки, а также данным 2D-сейсморазведки высокого разрешения.

The purpose of the stratigraphic drilling in the development of the oil and gas potential of sedimentary basins is to compile the most reliable model of the geological structure of the studied region by obtaining a core from deep target horizons. The structure of Russian Arctic sedimentary basins allows to use the shallow wells for further study of the deep structure. An important stage in design of drilling operations is the selection of the optimal well location, which is largely based on the analysis of seismic data. Traditionally, the study of deep-lying target horizons within the framework of the prospecting and evaluation stage of geological exploration is carried out according to 2D seismic data of standard resolution (2D SR). For the purposes of shallow-depth stratigraphic drilling, which is carried out in the near-surface section (NSS), standard approaches to processing 2D SR data are not optimal, methods of specialized processing of 2D SR materials have been developed, contributing to the improvement of vertical and horizontal resolution in NSS. The paper presents the results of a detailed study of the NSS structure to select the location of a shallow stratigraphic well in the outer sector of the Russian Federation Eastern Arctic shelf. The analysis of the structural features of the geological section in the De Long Rise was carried out according to 2D SR data after specialized processing, as well as high-resolution 2D seismic data.
IDENTIFICATION OF THE MAIN GEOLOGICAL AND GEOMORPHOLOGICAL COMPONENTS OF UNDERWATER LANDSCAPES BASED ON COMPLEX GEOLOGICAL AND GEOMORPHOLOGICAL DATA INTERPRETATION (KANDALAKSHA BAY, WHITE SEA)
Authors: Терёхина Я.Е. , Токарев М.Ю. , Рыбалко А.Е. , Замотина З.С. , Фрих-Хар А.Ю.
Published: August 2024

Представлены результаты применения методики комплексного анализа геолого-геофизических материалов для идентификации однородных геолого-геоморфологических областей, составляющих основу для распространения по площади точечной информации о составе и своеобразии распределения и состава донных биоценозов в районе Кандалакшского залива Белого моря. Комплексный подход к картированию подводных ландшафтов включает в себя как качественный, так и количественный анализ геолого-геофизических данных и последующее поэтапное уточнение выдвинутых предположений при детализации работ. Использование методов автоматической интерпретации требует тщательной подготовки входных данных: расчет и выбор атрибутов, отбраковка, нормализация. В то же время полученные результаты свидетельствуют об успешной реализации технологии сбора и анализа геофизических данных для картирования абиотических компонентов подводных ландшафтов на обширных территориях перигляциальных и гляциальных шельфов России.

The results of the application of the methodology of complex analysis of geological and geophysical data for the identification of homogeneous geological and geomorphological areas that form the basis for the dissemination of point information on the composition and originality of the distribution and composition of bottom biocenoses in the area of the Kandalaksha Bay of the White Sea are presented. An integrated approach to mapping underwater landscapes includes both “qualitative” and “quantitative” analysis of geological and geophysical data and subsequent step-by-step refinement of the assumptions made when detailing the work. The use of automatic interpretation methods requires a thorough preparation of the input data: calculation and selection of attributes, rejection, normalization. At the same time, the results suggest the successful implementation of the technology for collecting and analyzing geophysical data for mapping the abiotic components of underwater landscapes in the vast territories of the periglacial and glacial shelves of Russia.
ON THE QUESTION OF THE REGIONAL STATUS OF THE MODEL FOR FORECASTING THE STRENGTH OF SEDIMENTARY ROCKS IN SOUTH YAKUTIA
Authors: Нерадовский Л.Г.
Published: August 2024

В разных инженерно-геологических условиях изучены ошибки модели прогноза в водонасыщенном состоянии прочности осадочных пород Южной Якутии. Для этого применялось уравнение регрессии, полученное для осадочных пород г. Нерюнгри по данным метода дистанционного индуктивного зондирования. Установлены три тенденции ошибок. Первая тенденция – завышение прочности слабых пород (ниже 15 МПа) в среднем на 7,7–14,2%. Вторая тенденция – равновероятное завышение-занижение прочности доминирующих пород (15–120 МПа). Третья тенденция – занижение прочности очень крепких пород (выше 120 МПа) в среднем на 18,0–22,0%. В целом разброс ошибок с высоким уровнем доверия 80% не превышает ±32%. Близость такой совокупности ошибок к лабораторной ошибке ±20% доказывает гипотезу о региональном статусе модели прогноза прочности осадочных пород в области их распространения в Южной Якутии.

This study examined errors in the model predicting saturated strength for sedimentary rocks of southern Yakutia under different engineering-geological conditions. The regression equation derived for the city of Neryungri from geometric EMI sounding data was used. Three error trends were found: (1) strength overestimation for weak (<15 MPa) rocks, on average, by 7,7–14,2%; (2) equally probable overestimation or underestimation for dominant (15–120 MPa) rocks, and (3) underestimation for very strong (>120 MPa) rocks, on average, by 18,0–22,0%. Overall, the error scatter at 80% confidence level does not exceed ±32%. The proximity of this error population to the laboratory measurement error of ±20% proves the hypothesis about the regional status of the sedimentary rock strength prediction model of southern Yakutia.
CHARACTERISTICS OF THE FUNCTIONAL STATE OF THE CENTRAL NERVOUS SYSTEM IN MEN NORTHERNERS OF DIFFERENT AGE GROUPS
Authors: Рябова М.А.
Published: August 2024

Целью исследования было изучение показателей функционального состояния центральной нервной системы: скорости простой зрительно-моторной реакции и реакции выбора у северян мужского пола молодого и пожилого возраста. Было установлено, что, по сравнению с пожилыми испытуемыми, молодые мужчины имеют более высокий уровень функционального состояния ЦНС. Пожилые мужчины характеризуются дисбалансом нервных процессов с преобладанием процессов возбуждения, слабостью нервной системы и низкой стабильностью реакции.

The aim of the study was to study the indicators of the functional state of the central nervous system: the speed of a simple visual-motor reaction and the reaction of choice in male northerners of young and old age. It was found that, compared with the elderly subjects, young men have a higher level of the functional state of the CNS. Elderly men are characterized by an imbalance of nervous processes with a predominance of excitation processes, weakness of the nervous system, and low stability of the reaction.
THE RELATIONSHIP BETWEEN SLEEP QUALITY AND LEVEL OF PHYSICAL ACTIVITY OF STUDENTS AND HEART RATE VARIABILITY
Authors: Путилин Л.В.
Published: August 2024

Аннотация. Вариабельность сердечного ритма может зависеть от сна и двигательной активности. Степ-тест является методом оценки уровня максимального потребления кислорода, зависящего от величины двигательной активности. Сон может влиять на уровень кардиореспираторного фитнеса. Повышение двигательной активности способно снижать уровень стресса. Изучение их взаимного влияния на студентов медицинского института стало целью этого исследования.

Heart rate variability may depend on sleep and motor activity. The step-test is a method of assessing the level of maximum oxygen consumption, which depends on the amount of motor activity. Sleep can affect cardiorespiratory fitness levels. Increased motor activity can reduce stress levels. The study of their mutual influence on medical students was the purpose of this study.
MENTAL ADAPTATION OF CADETS TO THE EDUCATIONAL PROCESS IN A MILITARY UNIVERSITY
Authors: Кулганов В.А. , Башкирцев В.П. , Матюшенок К.В.
Published: August 2024

В статье рассматривается проблема психической адаптации курсантов в военном высшем учебном заведении. Раскрыты основные понятия, закономерности и особенности адаптации обучающихся, которые позволяют выявить причины их дезадаптации к образовательному процессу в военном вузе. Показаны основные группы курсантов по фактору психической адаптивности, а также направления совершенствования психолого-педагогического обеспечения обучающихся в динамике образовательной деятельности. Статья раскрывает профессорско-преподавательскому составу, командирам и начальникам возможности более эффективного подхода к профилактике девиантного поведения, предотвращению конфликтов, попыток суицидов и сокращению отчислений курсантов по субъективным причинам.

The article deals with the problem of mental adaptation of cadets in a military higher educational institution. The basic concepts, patterns and features of adaptation of students are revealed, which allow us to identify the causes of their maladaptation to the educational process in a military university. The main groups of cadets on the factor of mental adaptability are shown, as well as directions for improving the psychological and pedagogical support of students in the dynamics of educational activity. The article reveals to the teaching staff, commanders and superiors the possibilities of a more effective approach to the prevention of deviant behavior, the prevention of conflicts, suicide attempts and the reduction of students' deductions for subjective reasons.
THE POSSIBILITIES OF USING THE sLORETA METHOD FOR THE DIAGNOSIS OF BRAIN DAMAGE IN CARDIAC SURGERY PATIENTS IN THE PERIOPERATIVE PERIOD
Authors: Куприянова Д.С. , Тарасова И.В.
Published: August 2024

Диагностика периоперационного повреждения головного мозга и ассоциированных с ним когнитивных нарушений является нерешенным и активно развивающимся направлением современной медицины и нейрофизиологии. В настоящем обзоре рассмотрена возможность применения неинвазивного метода контроля деятельности мозга и изучения фундаментальных механизмов его работы - электроэнцефалографии (ЭЭГ) для оценки мозговой дисфункции в послеоперационном периоде кардиохирургических вмешательств. Особый интерес представляет современный метод обработки ЭЭГ-сигнала - sLORETA (стандартизированная электромагнитная томография головного мозга низкого разрешения). Продемонстрирована значимость этого метода при выявлении дисфункции уязвимых областей мозга у пациентов с болезнью Альцгеймера, с инсультом, черепномозговой травмой. Рассматриваются перспективы использования томографии головного мозга низкого разрешения для диагностики мозгового повреждения у кардиохирургических пациентов в периоперационном периоде. Подчеркивается, что исследований, посвященных изучению патофизиологических механизмов когнитивных нарушений с использованием цифровых технологий обработки ЭЭГ-сигнала, недостаточно, и требуется их дальнейшее развитие. К

Diagnosis of perioperative brain damage and associated cognitive disorders is an unresolved and actively developing area of modern medicine and neurophysiology. This review considers the possibility of using a non-invasive method of monitoring brain activity and studying the fundamental mechanisms of its work - electroencephalography (EEG) to assess brain dysfunction in the postoperative period of cardiac surgery. Of particular interest is the modern method of processing the EEG signal - sLORETA (standardized low resolution brain electromagnetic tomography). The significance of this method in detecting dysfunction of vulnerable areas of the brain in patients with Alzheimer's disease, stroke, and traumatic brain injury has been demonstrated. The prospects of using low-resolution brain tomography for the diagnosis of brain damage in cardiac surgery patients in the perioperative period are considered. It is emphasized that the studies devoted to the study of the pathophysiological mechanisms of cognitive impairment using digital technologies of EEG signal processing, are insufficient, and their further development is required.
PSYCHOPHYSIOLOGICAL STATUS OF CHINESE STUDENTS WITH IMPAIRED HEALTH IN THE FIRST YEAR OF STUDY IN RUSSIA
Authors: Милашечкин В.С. , Гернет М.С.
Published: August 2024

В статье отражены результаты исследования влияния пребывания студентов из Китая с заболеваниями органов зрения и ЦНС в первый год обучения в России на некоторые показатели психофизиологической адаптации их организма. Исследование проводилось на кафедре физического воспитания и спорта РУДН. Определяли индивидуальную единицы времени и воспроизведение длительности временного интервала светового и звукового раздражителей. Выявили более низкие значения психофизиологических показателей адаптационных резервов у студентов из Китая с заболеваниями ЦНС и органов зрения в первый год пребывания в России по сравнению с российскими студентами, имеющими аналогичные заболевания.

The article reflects the results of a study of the impact of students from China with diseases of the visual organs and central nervous system in the first year of study in Russia on some indicators of psychophysiological adaptation of their body. The study was conducted at the Department of Physical Education and Sports of the RUDN. The individual units of time and reproduction of the duration of the time interval of light and sound stimuli were determined. Revealed lower values of psychophysiological indicators of adaptive reserves in students from China with diseases of the central nervous system and visual organs in the first year of stay in Russia compared with Russian students.
FEATURES OF VOCATIONAL EDUCATIONPERSONS WITH HEARING IMPAIRMENTIN MODERN SOCIO-PEDAGOGICAL CONDITIONS
Authors: Пшеничнова Е.Э.
Published: August 2024

В статье рассматриваются социально-педагогический опыт и процесс развития профессионального образования лиц с нарушением слуха. Раскрываются возможности учащихся с нарушением слуха в освоении доступных и востребованных профессий в современных социально-педагогических условиях.

. The article deals with the socio-pedagogical experience and the process of development of professional education of persons with hearing impairment. The possibilities of students with hearing impairment in mastering accessible and sought-after professions in modern socio-pedagogical conditions are revealed.
INDICATORS` FEATURES OF REGULATORY SYSTEMS ACTIVITY IN WOMEN OF REPRODUCTIVE AGE WHO REGULARLY DO FITNESS
Authors: Южакова А.А.
Published: August 2024

.Целью исследования была оценка показателей активности регуляторных систем у женщин репродуктивного возраста, регулярно занимающихся фитнесом, с различным исходным тонусом ВНС. На примере этих групп женщин было установлено благоприятное адаптационное влияние данного вида гиперкинезий на активность регуляторных систем.

The purpose of the study was to evaluate the indicators of the activity of regulatory systems in women of reproductive age, regularly engaged in fitness, with different initial tone of the ANS. On the example of these groups of women, a favorable adaptive effect of this type of hyperkinesia on the activity of regulatory systems was established. K
FORMATION OF PROFESSIONAL COMPETENCE OF FUTURE TEACHERS OF THE DEEP IN THE CONDITIONS OF PRACTICE-ORIENTED TRAINING
Authors: Филиппова М.И.
Published: August 2024

В статье рассматривается понятия компетенции и компетентность, проведено исследование реализации Автором изучено научно-теоретическое и экспериментальное изучение процесса формирования профессиональной компетентности студентов-сурдопедагогов в условиях реализации новых образовательных стандартов высшего образования, а именно у студентов, обучающихся по направлению подготовки 44.03.03 «Специальное (дефектологическое) образование», направленность (профиль) «Сурдопедагогика (Начальное образование детей с нарушением слуха)».

The article discusses the concepts of competence and competency, conducted a study of implementation. The author studied a scientific, theoretical and experimental study of the process of formation of professional competence of students-teachers of the deaf in the context of the implementation of new educational standards of higher education, namely among students studying in the field of training 44.03.03«Special (defectological) education» in the profile “Deaf Pedagogy (Primary education of children with hearing impairment)».
SOME FEATURES OF THE DYNAMICS OF MANUAL ASYMMETRY
Authors: Сычев В.С. , Давыдова С.С.
Published: August 2024

Исследована и проанализирована динамика мануальной асимметрии в разных условиях обучения и тренировочных занятий у юношей и девушек. Обнаружена тенденция формирования коэффициента праворукости в зависимости от особенностей организации функциональной системы, необходимой для достижения полезного результата. Конкретные особенности мануальной асимметрии, по-видимому, определяются спецификой двигательной или иной активности.

The dynamics of manual asymmetry in different conditions of training and training sessions in boys and girls has been studied and analyzed. The tendency of the formation of the right-handedness coefficient depending on the features of the organization of the functional system necessary to achieve a useful result is found. The specific features of manual asymmetry, apparently, are determined by the specifics of motor or other activity.