bluuebunny/crossref_metadata_2025 huggingface dataset:
A longitudinal change of syndecan-1 predicts risk of acute respiratory distress syndrome and cumulative fluid balance in patients with septic shock: a preliminary study
Authors: Kajita Yuka , Terashima Tsuguaki , Mori Hisatake , Islam Md. Monirul , Irahara Takayuki , Tsuda Masanobu , Kano Hideki , Takeyama Naoshi
Published: April 2021

Background

The purpose of this study is to investigate the time course of syndecan-1 (Syn-1) plasma levels, the correlation between Syn-1 and organ damage development, and the associations of Syn-1 level with cumulative fluid balance and ventilator-free days (VFD) in patients with septic shock.

Methods

We collected blood samples from 38 patients with septic shock upon their admission to ICU and for the first 7 days of their stay. Syn-1 plasma level, acute respiratory distress syndrome (ARDS), other organ damage, VFD, and cumulative fluid balance were assessed daily.

Results

Over the course of 7 days, Syn-1 plasma levels increased significantly more in patients with ARDS than in those without ARDS. Patients with high levels of Syn-1 in the 72 h after ICU admission had significantly higher cumulative fluid balance, lower PaO2/FiO2, and fewer VFD than patients with low levels of Syn-1. Syn-1 levels did not correlate with sequential organ failure assessment score or with APACHE II score.

Conclusions

In our cohort of patients with septic shock, higher circulating level of Syn-1 of cardinal glycocalyx component is associated with more ARDS, cumulative positive fluid balance, and fewer VFD. Measurement of Syn-1 levels in patients with septic shock might be useful for predicting patients at high risk of ARDS.
Tilt and strain change during the explosion at Minami-dake, Sakurajima, on November 13, 2017
Authors: Hotta Kohei , Iguchi Masato
Published: April 2021

We herein propose an alternative model for deformation caused by an eruption at Sakurajima, which has been previously interpreted as being due to a Mogi-type spherical point source beneath Minami-dake. On November 13, 2017, a large explosion with a plume height of 4200 m occurred at Minami-dake. During the 3 min following the onset of the explosion (November 13, 2017, 22:07–22:10 (Japan standard time (UTC + 9); the same hereinafter), phase 1, a large strain with changes up to 120 nstrain was detected at the Arimura observation tunnel (AVOT) located approximately 2.1 km southeast from the Minami-dake crater. After the peak of the explosion (November 13, 2017, 22:10–24:00), phase 2, a large deflation was detected at every monitoring station due to the continuous Strombolian eruption. Subsidence toward Minami-dake was detected at five out of six stations, whereas subsidence toward the north of Sakurajima was detected at the newly installed Komen observation tunnel (KMT), located approximately 4.0 km northeast from the Minami-dake crater. The large strain change at AVOT as well as small tilt changes at all stations and small strain changes at the Harutayama observation tunnel (HVOT) and KMT during phase 1 can be explained by a very shallow deflation source beneath Minami-dake at 0.1 km below sea level (bsl). For phase 2, a deeper deflation source beneath Minami-dake at a depth of 3.3 km bsl was found in addition to the shallow source beneath Minami-dake, which turned inflation after the deflation that occurred during phase 1. However, this model cannot explain the tilt change of KMT. Adding a spherical deflation source beneath Kita-dake at a depth of 3.2 km bsl can explain the tilt and strain change at KMT and the other stations. The Kita-dake source was also found in a previous study of long-term ground deformation. Not only the deeper Minami-dake sourceMD, but also the Kita-dake source deflated due to the Minami-dake explosion.
“Since I’m a little bit more mature”: contraception and the arc of time for women in midlife
Authors: Alspaugh Amy , Reibel Melody D. , Im Eun-Ok , Barroso Julie
Published: April 2021

Background

Contraceptive methods have rapidly evolved over the past several decades, but little research has explored how women interact with contraception over time. Exploring contraceptive beliefs, perceptions, and attitudes of women in midlife can reveal much about how lived experience affects contraceptive decisions and reproductive health choices.

Methods

Individual, semi-structured interviews were conducted with 20 women between the ages of 40 and 55 who had not reached menopause and did not have a permanent method of sterilization. Data were coded using qualitative descriptive methods.

Results

Three major themes were identified: 1) journey toward empowerment; 2) finding the right fit: evolution over time; and 3) anticipating a transition. Past experiences with or fear of side effects and hormones were common reasons to change or avoid certain contraceptive methods. Most participants were happy with their contraceptive method; however, those who were unhappy were more likely to vocalize fatigue at continuing to need contraception as menopause approached.

Conclusion

Approaching contraceptive counseling from a place that considers the journey with contraception over a reproductive life span will help identify how beliefs, perceptions, and attitudes of women affect their contraceptive practices and choices.
Re: Concept and application of relaxing radial retinectomy for retinal detachment with advanced proliferative vitreoretinopathy
Authors: Grabowska Anna , Neffendorf James E. , Williamson Tom H.
Published: April 2021

The following is a response to the recent review article by Girsang and colleagues (Int J Retina Vitreous. 2020;6:46), who describe concept and application of relaxing radial retinectomy for retinal detachment with advanced proliferative vitreoretinopathy. We discuss the distribution of the retinal nerve fiber layer, an aspect not touched on by the authors, and the importance of its consideration in determining visual field outcomes when performing retinectomy. Moreover, we share our clinical experience with both radial and circumferential retinectomy and discuss scenarios where the combination of both is more effective.
Predicting factors of intradialytic hypotension in the last half of hemodialysis therapy
Authors: Aoyama Yumi , Kajimoto Katsuya , Hori Maiko , Otsubo Shigeru , Nitta Kosaku
Published: April 2021

Background

Intradialytic hypotension (IDH) is one of the most frequent complications of hemodialysis. IDH alters a patient’s quality of life and has a strong association with mortality. IDH mainly occurs when ultrafiltration during hemodialysis exceeds the pace of the plasma refill. Ultrasonography has been used to evaluate the intravascular volume status. We evaluated the association between IDH and baseline laboratory data or ultrasound findings during IDH during the latter half of a hemodialysis session.

Methods

Sixty-two patients who underwent hemodialysis were enrolled in this study. The peak early mitral inflow wave velocity (peak E-velocity), the inferior vena cava (IVC) dimensions, and number of B-lines were estimated at two time points (just after the start and at the midpoint of the hemodialysis session). We compared the parameters between the patients without IDH throughout the hemodialysis session (non-IDH group) and patients with IDH only during the latter half of the hemodialysis session (IDH in the latter half group).

Results

Of the 62 study participants, 28 patients were in non-IDH group, and 16 patients were in IDH in the latter half group. The serum sodium level was significantly lower in the IDH in the latter half group (135 ± 4 mEq/L) than in the non-IDH group (138 ± 4 mEq/L) (P = 0.015). The rate of decrease of the peak E-velocity was significantly higher in the IDH in the latter half group (0.33 ± 0.13) than in the non-IDH group (0.24 ± 0.14) (P = 0.037). The best cutoff point of the serum level of sodium was 137 mEq/L, with a sensitivity of 68.8% and specificity of 64.3%. The area under the receiver operating characteristic (ROC) curve was 0.71. The best cutoff point of the rate of decrease of the peak E-velocity was 0.295, with a sensitivity of 73.3% and a specificity of 71.4%. The area under the ROC curve was 0.71.

Conclusions

A low serum level of sodium at baseline and an early decrease in the peak E-velocity during hemodialysis may be related to intradialytic hypotension in the latter half of a hemodialysis session. Careful observation may be needed in the hemodialysis patients in whom the serum level of sodium is below 137 mEq/L or the rate of decrease of the peak E-velocity is over 0.295.
Valorization of pikliz: a spicy meal garnishment in Haitian cuisine
Authors: Louis-Jean James , Sanon Debbie , Louis-Jean Kevin , Sanon Nicole , Stvil Louis-Jean Ruthonce , Thomas Michelle Luvy
Published: April 2021

The biochemical process of fermentation (zymology) is widely practical for foods and beverages. This metabolic process involves microorganisms (bacteria) and their enzymes in the preparation and preservation of foods. Many studies have shown that fermented foods and beverages have various documented health benefits to humans, such as being high in vitamin b, and, among other benefits, having atherogenic and anticarcinogenic properties. This communication discusses the significance of fermentation in Haitian cuisine by focusing onpikliz—a spicy fermented meal garnishment that is widely popular among Haitian dishes. This analysis provides relevant information on Haitian cuisine while examining the underlying mechanisms, compositions, properties, nutritional values, and potential health benefits ofpikliz.This spicy meal garnishment represents the regional, ethnic, and national identity of Haitians living in Haiti and abroad.
Coastal green infrastructure to mitigate coastal squeeze
Authors: Chávez Valeria , Lithgow Debora , Losada Miguel , Silva-Casarin Rodolfo
Published: April 2021

Infrastructure is necessary to protect and provide the goods and services required by humans. As coastal green infrastructure (CGI) aims to respect and work with natural processes, it is a feasible response to mitigate or avoid the consequences of coastal squeeze. The concept of CGI is receiving increased attention of late due to the challenges facing us, such as climate change, population growth and the overexploitation of natural resources on the coast. Terms which may be applied to encourage the construction of infrastructure, or to minimize the responsibility for poorly made decisions, often induce misunderstanding. In this paper, the concept of CGI and its use in solving coastal problems is reordered. Four categories are proposed, according to the degree of naturalness of the project: Nature reclamation, Engineered ecosystems, Ecologically enhanced engineering, and De-engineering/Relocation. Existing coastal risk evaluation frameworks can be used to design many types of CGI. Key concepts, challenges and good practices for the holistic management of coastal squeeze are presented from the analysis of successful and unsuccessful CGI projects worldwide.
Pore structure and fractal characteristics of ultralow-permeability sandstone reservoirs in the Upper Triassic Yanchang Formation, Ordos Basin
Authors: Zhang Quanpei , Jiao Tao , Huang Hao , Qi Zhao , Jiang Tao , Chen Gang , Zhu Yushuang , Jia Na
Published: April 2021

The complex pore structure and high heterogeneity of ultralow-permeability sandstone reservoirs have a significant effect on reservoir quality evaluation and hydrocarbon resource assessment. We collected 10 reservoir samples from the Upper Triassic Yanchang Formation Chang 8 in the Zhenbei area of the Ordos Basin. We measured the pore size distribution (PSD) and fluid occurrence characteristics of the reservoir by pressure-controlled porosimetry, rate-controlled porosimetry, and nuclear magnetic resonance, and then we analyzed the results via the fractal theory to determine the pore space fractal characteristics. Our analysis indicates that the three major pore types of these reservoirs are residual intergranular pores, dissolution pores, and intercrystalline pores. The pore structure of the ultralow-permeability sandstone reservoirs is highly heterogeneous with pore throats of various scales, and the corresponding fractal characteristics are notably different, exhibiting multifractal features. Compared with macropores and mesopores, micropores are more uniform and regular in terms of their PSD and thus only slightly influence the reservoir quality. The complexity of the throat distribution and whole pore space is attributed to the development of dissolution pores and the content of feldspar minerals. Fractal features depend on the movable fluid pore space and effective pores, whose fractal dimensions reflect the complexity of interconnected pores and correlate well with the porosity and permeability. The development of different types and sizes of pore throats in these ultralow-permeability sandstone reservoirs resulted in the observed pore structure heterogeneity. The difference in mineral composition and content of these reservoirs aggravates the pore structure complexity and affects the reservoir quality evaluation and further oilfield development.
Evaluating proxies for the drivers of natural gas productivity using machine-learning models
Authors: Kumar Abhash , Harbert William , Hammack Richard , Zorn Erich , Bear Alexander , Carr Timothy
Published: April 2021

The extensive development of unconventional reservoirs using horizontal drilling and multistage hydraulic fracturing has generated large volumes of reservoir characterization and production data. The analysis of this abundant data using statistical methods and advanced machine-learning (ML) techniques can provide data-driven insights into well performance. Most predictive modeling studies have focused on the impact that different well completion and stimulation strategies have on well production but have not fully exploited the available in situ rock property data to determine its role in reservoir productivity. We have used machine-learning techniques to rank rock mechanical properties, microseismic attributes, and stimulation parameters in the order of their significance for predicting natural gas production from an unconventional reservoir. The data for this study came from a hydraulically fractured well in the Marcellus Shale in Monongalia County, West Virginia. The data classes included measurements aggregated by well completion stage that included (1) gas production, (2) well-log-derived measurements including bulk density, elastic moduli, shear impedance, compressional impedance, brittleness, and gamma measurements, (3) microseismic attributes, (4) long-period long-duration (LPLD) event counts, (5) fracture counts, and (6) stimulation parameters that included the fluid injection volume and average pumping pressure. To identify observable proxies for the drivers of gas production, we evaluated five commonly used ML approaches including multivariate adaptive regression spline, Gaussian mixture model, random forest, gradient boosting, and neural network. We selected five variables including LPLD event count, seismogenic b-value, hydraulic diffusivity, cumulative moment, and fluid volume as the features most likely to impact gas productivity at the stage level in the study area. The data-driven selection of these parameters for their importance in determining gas production can help reservoir engineers design more effective hydraulic-fracture treatments in the Marcellus Shale and other similar unconventional reservoirs.

Plain language summary: We use machine-learning methods and data-driven selection of reservoir parameters to rank and better understand their importance in determining gas production, which can help reservoir engineers design more effective hydraulic-fracture treatments in the Marcellus Shale and other similar unconventional reservoirs.
A Remote Surveillance Platform to Monitor General Care Ward Surgical Patients for Acute Physiologic Deterioration
Authors: Safavi Kyan C. , Deng Hao , Driscoll William , Nikolov Milcho , Tolia Kalpan , Wiener-Kronish Jeanine P.
Published: April 2021

BACKGROUND:

The traditional paradigm of hospital surgical ward care consists of episodic bedside visits by providers with periodic perusals of the patient’s electronic health record (EHR). Vital signs and laboratory results are directly pushed to the EHR but not to providers themselves. Results that require intervention may not be recognized for hours. Remote surveillance programs continuously monitor electronic data and provide automatic alerts that can be routed to multidisciplinary providers. Such programs have not been explored in surgical general care wards.

METHODS:

We performed a quality improvement observational study of otolaryngology and ophthalmology patients on a general care ward from October 2017 to March 2019 during nighttime hours (17:00–07:00). The study was initiated due to the loss of on-site anesthesiology resources that historically helped respond to acute physiologic deterioration events. We implemented a remote surveillance software program to continuously monitor patients for severe vital signs and laboratory abnormalities and automatically alert the ward team and a remote critical care anesthesiology team. The primary end point was the true positive rate, defined as the proportion of alerts that were associated with a downstream action that changed the care of the patient. This was determined using systematic chart review. The secondary end point, as a measure of alarm fatigue, was the average number of alerts per clinician shift.

RESULTS:

The software monitored 3926 hospital visits and analyzed 1,560,999 vitals signs and 16,635 laboratories. It generated 151 alerts, averaging 2.6 alerts per week. Of these, 143 (94.7%) were numerically accurate and 8 (5.3%) were inaccurate. Hypoxemia with oxygen saturation <88% was the most common etiology (92, 63%) followed by tachycardia >130 beats per minute (19, 13.3%). Among the accurate alerts, 133 (88.1%) were true positives with an associated clinical action. Actions included a change in management 113 (67.7%), new diagnostic test 26 (15.6%), change in discharge planning 20 (12.0%), and change in level of care to the intensive care unit (ICU) 8 (4.8%). As a measure of alarm fatigue, there were 0.4 alerts per clinician shift.

CONCLUSIONS:

In a surgical general care ward, a remote surveillance software program that continually and automatically monitors physiologic data streams from the EHR and alerts multidisciplinary providers for severe derangements provided highly actionable alarms at a rate that is unlikely to cause alarm fatigue. Such programs are feasible and could be used to change the paradigm of monitoring.
Ausgrabungen und Funde im Jahr 2013
Authors: Allemann Martin , Bernasconi Marco , Matt Christoph , Scholz Till , Spichtig Norbert
Published: April 2021

Berichte zu den archäologischen Untersuchungen der Archäologischen Bodenforschung Basel-Stadt im Jahr 2013.
Vorwort und Impressionen
Authors: Lassau Guido
Published: April 2021

Vorwort des Kantonsarchäologen Guido Lassau und Impressionen aus dem Berichtsjahr 2014.
Fundchronik: Ausgrabungen und Funde im Jahr 2014
Authors: Bernasconi Marco , Imbach Marta , Rentzel Philippe , Scholz Till , Spichtig Norbert , Pümpin Christine
Published: April 2021

Berichte zu den archäologischen Untersuchungen der Archäologischen Bodenforschung Basel-Stadt im Jahr 2014.
DETECÇÃO REMOTA DOS POTENCIAIS EFEITOS DE SECAS INTENSAS SOBRE A SAZONALIDADE DA ÁGUA NO COMPLEXO FLUVIO-LACUSTRE DO CURUAÍ, RIO AMAZONAS, PARÁ, BRASIL
Authors: De Lima Joelson Leal , Silva Sousa Keid Nolan , Santos Paulo Roberto Brasil
Published: April 2021

Introdução: estudos revelam que a região amazônica é vulnerável a extremos climáticos como secas, nesse contexto, o sensoriamento remoto juntamente com outras ferramentas de análise espacial, têm sido largamente utilizados para o monitoramento de atividades ambientais, incluindo este fenômeno natural, e melhorando continuamente medições espaciais e temporais. Objetivo: monitorar os efeitos de uma seca extrema sobre a sazonalidade hídrica do sistema lacustre do Curuaí, rio Amazonas, estado do Pará, Brasil; através da utilização de geotecnologias como sensoriamento remoto e SIG. Métodos: o presente trabalho fez uso de uma serie temporal de imagens Landsat-5, período de vazão e seca do ano de 2010; com aplicação do NDWI - Índice de Diferença Normalizada da Água, e posterior vetorização do contorno deste corpo hídrico, para determinação da porcentagem de redução da área de lâmina d’água nos meses mais significativos, e compilação de informações associadas. Resultados: O NDWI sobre a serie temporal mostrou resultados satisfatórios no realce da superfície aquática, permitindo realizar o zoneamento destas áreas e comparação de sua porcentagem redutiva, que mostrou efeitos potencialmente prejudiciais, com redução de 1.524 km2 para 338, 851 km2. Conclusão: O índice aplicado obteve resultados satisfatórios, demostrando quanto estas geotecnologias, e suas técnicas de extração de informações, podem ser eficazes no monitoramento de fenômenos naturais potencialmente prejudiciais sobre a região de estudo; com isso, através de estudos mais avançados, podem ser eficazes para o planejamento de estratégias de mitigação desses impactos sobre os diversos ecossistemas da Amazônia.
Analysis of FDA Novel Drug Approvals
Authors: Kumar Shukla Ajay , Shukla Kumar , Mehani Rekha , Jain Swati , Maqsood Sheema
Published: April 2021

Background: United States Food and Drug Administration (FDA) is the fastest drug review agency in the world. FDA is responsible for the protection of public health by assuring that foods are safe, wholesome, sanitary and, properly labeled. Novel drug Approvals are usually innovative products to serve unmet medical needs or otherwise help to advance patient care. Methods: FDA novel drug approvals were analyzed from calendar year (CY) 2012 to 2018 based on not only their numbers but also BASED ON their impact, innovation, access, and predictability. Results: The total number of novel drugs approved from CY 2012 to 2018 was 279 (average 40 novel drugs/ year). Impact of novel drug approvals: 50% were first in class and 43% were for rare diseases. Overall expedited development and review methods were used in 63% of the novel drug approvals. Access of novel drug approvals: 84% were first-cycle approval, 74% were approved in the US before other countries, 58% priority reviews among novel drug approvals. Predictability of novel drug approvals: 98% approvals able to meet PDUFA goal dates for application review. Conclusions: Novel drug approvals during CY 2012-2018 had a high quality which is very much evident by their high impact, good access, and high predictability.
Surface acoustic microwave photonic filters in standard silicon-on-insulator
Authors: Katzman Moshe , Munk Dvir , Priel Maayan , Grunwald Etai , Hen Mirit , Inbar Naor , Feldberg Moshe , Sharabani Tali , Zektzer Roy , Bashan Gil , Vofsi Menachem , Levy Uriel , Zadok Avi
Published: April 2021

The processing of analog microwave-frequency signals using optical means becomes increasingly important as part of advanced cellular networks. Chip-level integration of microwave photonic filters, particularly in silicon, is considered necessary for their large-scale deployment. Discrete-time, delay-and-sum filters are widely used to select narrow spectral bands out of broad optical bandwidths. However, the long delays that are required to obtain narrowband filters are difficult to accommodate in integrated optic waveguide paths. In this work, we report discrete-time, integrated microwave photonic filters on standard silicon-on-insulator. Long delays are realized through the conversion of incoming radio-frequency modulation to the form of slow-moving surface acoustic waves. Conversion relies on thermo-elastic expansion of metallic gratings and does not involve piezoelectricity. Information is recovered in the optical domain via photoelastic modulation of probe light in a resonator waveguide. The resonator is patterned to support multiple delayed modulation events. Filters having up to 12 taps are demonstrated, with 175 ns-long delays and passbands as narrow as 5 MHz. The magnitude and radio-frequency phase of each filter tap are designed arbitrarily, independent of those of all others. The coherent summation of delayed waveform replicas is free of environmental phase drifts. Surface acoustic wave modulation of a compact, defect grating waveguide is demonstrated as well. Surface acoustic wave devices can significantly extend the signal-processing capabilities of silicon photonics.
Mapping of sequences in the 5’ region and 3’ UTR of tomato ringspot virus RNA2 that facilitate cap-independent translation of reporter transcripts in vitro
Authors: Paudel Dinesh Babu , Sanfaçon Hélène
Published: April 2021

Tomato ringspot virus (ToRSV, genus Nepovirus, family Secoviridae, order Picornavirales) is a bipartite positive-strand RNA virus, with each RNA encoding one large polyprotein. ToRSV RNAs are linked to a 5’-viral genome-linked protein (VPg) and have a 3’ polyA tail, suggesting a non-canonical cap-independent translation initiation mechanism. The 3’ untranslated regions (UTRs) of RNA1 and RNA2 are unusually long (~1.5 kb) and share several large stretches of sequence identities. Several putative in-frame start codons are present in the 5’ regions of the viral RNAs, which are also highly conserved between the two RNAs. Using reporter transcripts containing the 5’ region and 3’ UTR of the RNA2 of ToRSV Rasp1 isolate (ToRSV-Rasp1) and in vitro wheat germ extract translation assays, we provide evidence that translation initiates exclusively at the first AUG, in spite of a poor codon context. We also show that both the 5’ region and 3’ UTR of RNA2 are required for efficient cap-independent translation of these transcripts. We identify translation-enhancing elements in the 5’ proximal coding region of the RNA2 polyprotein and in the RNA2 3’ UTR. Cap-dependent translation of control reporter transcripts was inhibited when RNAs consisting of the RNA2 3’ UTR were supplied in trans. Taken together, our results suggest the presence of a CITE in the ToRSV-Rasp1 RNA2 3’ UTR that recruits one or several translation factors and facilitates efficient cap-independent translation together with the 5’ region of the RNA. Non-overlapping deletion mutagenesis delineated the putative CITE to a 200 nts segment (nts 773–972) of the 1547 nt long 3’ UTR. We conclude that the general mechanism of ToRSV RNA2 translation initiation is similar to that previously reported for the RNAs of blackcurrant reversion virus, another nepovirus. However, the position, sequence and predicted structures of the translation-enhancing elements differed between the two viruses.
Um preâmbulo ao curso O Poder psiquiátrico: o problema da antipsiquiatria em Foucault (ou a genealogia de uma a-historicidade)
Authors: Ribeiro Carlos Eduardo
Published: April 2021

Como um preâmbulo à leitura de O poder psiquiátrico, o artigo discute como a questão da antipsiquiatria deve ser a chave de leitura do curso dado por Foucault entre 1973-1974 no Collège de France. A antipsiquiatria está associada ao paradoxo que constituiu o saber psiquiátrico segundo o qual, ao procurar determinar a doença mental, o poder psiquiátrico eliminou o sofrimento real do indivíduo adoecido. O poder psiquiátrico teria como sua tese mais básica a proposta de que sobre o campo psiquiátrico é necessário fazer a genealogia desta forma de a-historicidade. Para tanto recorremos a textos, de certo modo, externos ao curso nos quais o tema se apresenta mais especificamente desenvolvido: a conferência História da loucura e antipsiquiatria (proferida em maio de 1973) e o resumo do curso.
El aporte de la filosofía y la cultura a la vida buena de un cuerpo precario
Authors: Genis Andrea Diáz
Published: April 2021

Resumen: ¿Se puede llevar un buena vida a partir de una vida mala? A partir de esta pregunta que se hace Butler, tenemos el propósito de reflexionar sobre el caso de César González (ex “pibe chorro” de la villa miseria en Argentina que llega a salir de esa situación y se convierte en escritor y cineasta), a partir del enfoque de capacidades de Martha Nussbaum y la importancia que tiene en la formación humana el cuidado de sí (concepto trabajado por nosotros a partir del último Foucault),  la inquietud y el autoconocimiento. Es también una reflexión sobre la importancia de la filosofía ligada al desarrollo humano, al pensamiento crítico y la imaginación creativa y es una reflexión sobre el alcance y la relevancia que tiene la educación y la cultura en la transformación de los sujetos y su vida.

Palabras-clave: Vidas precarias. Enfoque de capacidades. Cuidado de sí. César González.

The contribution of philosophy and culture to the good life of a precarious body

Abstract: Can you left a good life from a bad life? From this question asked by Butler, we have the purpose of reflecting on the case of César Gonzalez ( ex criminal of the misery village in Argentina that comes out of that situation and becomes a writer and filmmaker). Based on Martha Nussbaum's capabilities approach and the importance of caring for oneself in human formation (concept worked by us since the last Foucault), self-care and self-knowledge. It is also a reflection on the importance of philosophy linked to human development, critical thinking and creative imagination and is a reflection on the scope and relevance of education and culture in the transformation of subjects and their lives.

Keywords: Precarious lives. Capability Approach. Self of care. César González.

A contribuição da filosofia e da cultura para a boa vida de um corpo precário

Resumo: Você pode levar uma vida boa no meio de uma vida ruim? A partir desta pergunta feita por Butler, temos o objetivo de refletir sobre o caso de César González (ex-criminoso da vila da miséria na Argentina que sai dessa situação e se torna escritor e cineasta), com base na abordagem As capacidades de Martha Nussbaum e a importância do autocuidado na formação humana (conceito trabalhado por nós desde o último Foucault), inquietação e autoconhecimento. É também uma reflexão sobre a importância da filosofia ligada ao desenvolvimento humano, pensamento crítico e imaginação criativa e uma reflexão sobre o escopo e a relevância da educação e cultura na transformação dos sujeitos e de suas vidas.

Palavras-chave: Vidas precárias. Foco nas capacidades. Autocuidado. César González.
Apresentação do Dossiê Entre o governo das diferenças e os corpos ingovernáveis:
Authors: Pagni Pedro Angelo , Silva Divino J. da
Published: April 2021

Esperamos que este dossiê possibilite aos leitores uma reflexão sobre a problemática geral do governo das diferenças e dos corpos ingovernáveis, particularmente, que encontrem nesse conjunto de artigos algumas respostas para o enfrentamento da face obscura do biopoder no presente. Nossa expectativa também é a de que os eventuais impactos que esses corpos e suas alianças com a arte produzem na formação humana e em sua educação filosófica, tragam tanto à filosofia da educação quanto ao ensino de filosofia alguma oxigenação, quem sabe, entusiasmando-nos a extrapolar os pensamentos, práticas de pesquisa e de ensino, que também são nossas.
Arte, educación y comunidad en la estética pedagógica
Authors: Massó Castilla Jordi
Published: April 2021

Arte, educación y comunidad en la estética pedagógica

Resumen: Una de las corrientes estéticas contemporáneas más pujantes, la «estética pedagógica», planteó desde sus comienzos la combinación entre el arte y la educación. Las creaciones respaldadas por esta orientación se basan en muchas de las ideas de las pedagogías críticas de los años 60 e igualmente en los presupuestos de las llamadas últimas vanguardias artísticas. Todas ellas comparten un mismo espíritu emancipador en sintonía con las teorías más críticas con la sociedad de producción capitalista. Pero en los últimos años la «estética pedagógica» se ha visto empujada a problematizar la cuestión de la «comunidad» desde diferentes puntos de vista, partiendo de la base de que no puede haber educación ni arte sin un replanteamiento del espacio en común que ambos ponen en juego.

Palabras clave: Arte. Educación. Política. Comunidad.

Art, Education and Community in Pedagogical Aesthetics

Abstract: one of the most thriving contemporary aesthetic trends, «Pedagogical Aesthetics», raised from its beginnings the combination between art and education. The creations supported by this orientation are based on many of the ideas of the critical pedagogies of the 60s and also on the budgets of the so-called latest artistic avant-gardes. All of them share the same emancipatory spirit in tune with the most critical theories with the capitalist production society. But in recent years the «pedagogical aesthetic» has been pushed to problematize the question of «community» from different points of view, based on the fact that there can be no education or art without a rethinking of the common space that both put into play.

Keywords: Art. Education. Politics. Community

Arte, educação e comunidade em estética pedagógica

Resumo: uma das tendências estéticas contemporâneas mais prósperas, a «estética pedagógica», levantou desde o início a combinação entre arte e educação. As criações apoiadas por essa orientação baseiam-se em muitas das idéias das pedagogias críticas dos anos 60 e também nos orçamentos das chamadas vanguardas artísticas mais recentes. Todos eles compartilham o mesmo espírito emancipatório em sintonia com as teorias mais críticas da sociedade capitalista de produção. Mas, nos últimos anos, a «estética pedagógica» foi levada a problematizar a questão da «comunidade» de diferentes pontos de vista, com base no fato de que não pode haver educação ou arte sem repensar o espaço comum que ambos Eles colocam em jogo.

Palavras-chave: Arte. Educação. Política. Comunidade.

Data de registro:16/06/2020

Data de aceite: 22/07/2020
Fenomenologia e Educação na perspectiva de Creusa Capalbo
Authors: Marcondes César Constança Terezinha
Published: April 2021

Fenomenologia e Educação na perspectiva de Creusa Capalbo

Resumo: Creusa Capalbo fez seu doutorado em Filosofia na Universidade Católica de Louvain. Faleceu em 2017, aos 83 anos, e deixou uma obra centrada na meditação sobre Fenomenologia e Ciências Humanas. Editou um livro com esse título, cujo sexto capítulo aborda o tema Fenomenologia e Educação. Mostrando invulgar erudição e fazendo a crítica de pensadores que reduzem a educação à adequação ou à revolta contra a sociedade industrial, Creusa Capalbo entende que o papel da educação é o de propiciar a introdução de valores que assegurem a realização do bem comum. Inspira-se, para tanto, nas meditações exponenciais de Husserl, Scheler, Buber, dentre outros autores. Retomando as meditações desses pensadores, Creusa Capalbo realiza um percurso admirável, sublinhando sua fidelidade ao tema da Filosofia da Educação.Palavras-chave: Fenomenologia; Crítica filosófica; Educação; Bem-comum.

Phenomenology and Education from Creusa Capalbo’s perspective

Abstract: Creusa Capalbo did her PHD in Philosophy at the Catholic University of Louvain. She died in 2017, at the age of 83, and her work reflects the Phenomenology and the Human Sciences. In fact, she edited a book with that title, whose sixth chapter accounts the topics of Phenomenology and Education. Creusa Capalbo, with a lot of scholarship and criticizing the philosophers who reduce education to adequacy or to conflict against industrial society, she defends an education with values that support the realization of the common good. For this, she was inspired, among other philosophers, by Husserl’s, Scheler’s and Buber’s ideas. Resuming their thoughts, Creusa Capalbo did a great way, emphasizing her fidelity to the Philosophy of Education.Key Words: Phenomenology; Philosophical criticism; Education; Common good.

Phénoménologie et Éducation dans la perspective de Creusa Capalbo

Résumé: Creusa Capalbo a fait son doctorat en Philosophie dans l'Université Catholique de Louvain. Elle est décédée à 2017, avec 83 années, et elle a laissé une oeuvre axée sur la méditation au sujet de la Phénoménologie et les Sciences Humaines. Elle a publié un livre avec ce même titre, dont le 6ème chapitre étudie le sujet: Phénoménologie et Éducation. Sa remarcable érudition et sa critique des philosophes contemporains qui circonscrivent l'éducation soit à l'adéquation, soit à la révolte contre la société industrielle, l'amenèrent a affirmer que le rôle de l´éducation est celui de favoriser l'introduction dans la société des valeurs qui puissent assurér la réalisation du bien commun. Elle s'inspire, dans la proposition de cette perspective, dans les méditations de Husserl, Scheller, Buber, parmi d'autres penseurs, et elle réalise un parcours admirable, qui souligne sa fidélité au sujet de la philosophie de l'éducation.Mots clés: Phénoménologie; Critique philosophique; Éducation; Bien commun.

Data de registro: 20/08/2020Data de aceite: 30/11/2020
O terceiro-instruído: Ontofenomenologia e educação em Michel Serres
Authors: Valente Pinho Romana
Published: April 2021

O terceiro-instruído: Ontofenomenologia e educação em Michel Serres

Resumo: O terceiro-instruído: Ontofenomenologia e educação em Michel Serres é um estudo que visa compreender a relevância do pensamento ontofenomênico, epistemológico e educacional de Michel Serres para a implementação dessas categorias filosóficas: contrato natural (como oposição ao contrato social de Rousseau e como defensor do regresso à Terra inteira e ao Amor) e terceira-instrução. Nesse sentido, a importância da educação, comparada com a ontofenomenologia e a epistemologia, tornar-se-á maior e mais importante.Palavras-chave: Ontofenomenologia; Epistemologia; Educação; Michel Serres.

The third-instructed: Ontophenomenology and education in Michel Serres

Abstract: The third-instructed: Ontophenomenology and education in Michel Serres is a study which focus on understanding the relevance of ontophenomenal, epistemological and educational Serres’s thought for the implementation of these philosophical categories: natural contract (as opposition to Rousseau’s social contract and as a defender of the return to whole Earth and Love) and third-instruction. Therefore, the materiality of education comparing to ontophenomenology and epistemology will become greater and principal.Keywords: Ontophenomenology; Epistemology; Education; Michel Serres.

Le tiers-instruit: Ontophénoménologie et éducation à Michel Serres

Resumé: Le tiers-instruit: Ontophénoménologie et éducation à Michel Serres est une étude qui vise à comprendre la pertinence de la pensée ontophénoménal, épistémologique et éducatif de l’auteur pour accomplir ces catégories philosophiques: contrat naturel (par opposition au contrat social de Rousseau et en tant que défenseur du retour à la Terre entière et à l’Amour) et tierce-instruction. Donc, par rapport à ontophénoménologie et à épistémologie, l’importance de l´éducation deviendra plus grand et plus importante.Mots-clés: Ontophénoménologie; Épistémologie; Éducation; Michel Serres.Data de registro: 06/10/2020Data de aceite: 25/11/2020
Molecular Docking of Red Betel (Piper crocatum Ruiz & Pav) Bioactive Compounds as HMG-CoA Reductase Inhibitor
Authors: Zaelani Bella Fatima Dora , Safithri Mega , Andrianto Dimas
Published: April 2021

Cholesterol plaque buildup in artery walls occurs due to oxidation of Low-Density Lipoprotein (LDL) molecules by free radicals, which are a risk factor for coronary heart disease. Piper crocatum contains active compounds that can act as HMG-CoA reductase inhibitors, such as flavonoids, alkaloids, polyphenols, tannins, and essential oils. This study aimed to predict the potential of Piper crocatum extract and fraction compounds as HMG-CoA reductase inhibitors by investigating the ligand affinity to the HMG-CoA reductase enzyme. Ligand and receptor preparation was conducted using BIOVIA Discovery Studio Visualizer v16.1.0.15350 and AutoDock Tools v.1.5.6. Molecular docking used AutoDock Vina, while ligand visualization and receptor binding used PyMOL(TM) 1.7.4.5.Edu. The receptor used was HMG-CoA reductase (PDB code: 1HWK) with atorvastatin as a control ligand. Catechin, schisandrin B, and CHEMBL216163 had the highest inhibition with affinity energies of -7.9 kcal/mol, -8.2 kcal/mol, -8.3 kcal/mol, respectively. Amino acid residues that played a role in ligand and receptor interactions were Ser684, Asp690, Lys691, Lys692.
Antimicrobial Activities of Synthesized Silver Nanoparticles using Ethanol and Water Extract of Mirabilis Jalapa
Authors: Alam Tunas , Purnomo Frida Octavia , Tanjung Asbar
Published: April 2021

The focus of this study was to compare the antimicrobial activity of silver nanoparticles (AgNPs) synthesized using ethanol extracts (AgNPE) and water extracts (AgNPA) from four o’clock flowers (Mirabilis jalapa) against Staphylococcus aureus. AgNPs were characterized by UV-Vis diffraction, FTIR, SEM, and X-rays. UV-Vis analysis showed that AgNPA has an SPR band of about 460 nm and 530 nm for AgNPE, which proves the characteristics of the absorbance area of AgNPs. SEM images of AgNPE and AgNPA show a cuboid shape with a mean diameter of 80 and 30 nm, respectively and well dispersed. The response to the presence of polysaccharide biomolecules involved in forming AgNPs was analyzed using a Fourier transform infrared spectrometer. The result was that AgNPA and AgNPE have different reducing agents. The plant extracts, AgNPE and AgNPA, were studied for their antimicrobial activity against Staphylococcus aureus. The result was that both AgNPA and AgNPE showed good activity and showed that AgNPA with less inhibition was more effective than AgNPE.
Addition of Calcined Na2B4O7 on the Synthesis of Li7La3Zr2O12
Authors: Alaih Imam Shofid , Fathonah Sidiq , Nugrahaningtyas Khoirina Dwi , Rahmawati Fitria
Published: April 2021

Li7La3Zr2O12 (LLZO) is a garnet-type electrolyte for all-solid-state lithium-ion batteries (ASSB). It has good chemical and electrochemical stability against lithium and a relatively high ionic conductivity. However, the ionic conductivity needs to be further increased to provide a high specific capacity of the ASSB. Element doping into LLZO is an effort to increase molecular defect, known to enhance the conductivity. This research studied the effect of the Na2B4O7 addition on the LLZO synthesis, producing LLZBO(A). The investigation aims to understand whether the sodium ions dope into the LLZO structure during synthesis, or it is only B ions to enter into the structure. Therefore, another synthesis with B2O3 of B precursor was conducted for comparison (LLZBO(B)). The precursors were mixed stoichiometrically by following the formula of Li7-xLa3-xZr2-xBxNaxO12 (LLZBO, x= 0.15; 0.20; 0.30). XRD analysis equipped with Le Bail refinement found that LLZBO(A) and LLZBO(B) mainly consist of cubic and tetragonal LLZO with a %mol of 69.06 – 69.84 %, and the main secondary phase is La2Zr2O7. The surface morphology of LLZBO(A) and LLZBO(B) is almost similar to the irregular form of large aggregates. The particles become more dispersed when 0.3 %mol dopant was submitted. Impedance analysis found a high ionic conductivity of LLZBAO(A)0.3 1.042x10-3 Scm-1.
Posthumanistyczne echa, apokaliptyczne tony i zwierzęce odgłosy w filmach Bonga Joon-ho
Authors: Loska Krzysztof
Published: April 2021

The subject of the analysis in this article are three films by Bong Joon-ho: The Host (2006), Snowpiercer (2013) and Okja (2017), considered from the posthumanist perspective. A starting point is Donna Haraway’s suggestion that science-fiction stories should be treated as a tool for speculative thinking. Then, I point to the way the Korean film director demonstrates his critical reflection on the effects of climate change, deepening economic inequalities, the impact of global capitalism and the biopolitical model of the governance. The main aim is to seek out the possible strategies of resistance which enable humans to change their attitude to other species (Okja) and to ask a question about the scope of human freedom, the effects of our interference in the functioning of the biosphere (Snowpiercer) and the results of genetic modifications of animals.
Tele-kiss. Nam-June Paik’s expanded media in the light of Zen Buddhism
Authors: Lipiński Kamil
Published: April 2021

The article offers a broad overview of Nam-June Paik’s ideas of the expansion of video arts interpreted in the light of Zen Buddhism. His works recognized as the most significant examples of his marriage between the art theory and practice are marked by a thought-provoking vision of participatory culture, communicated in-between the networks in the post-industrial society. Our purpose is to reexamine his attitude to TV culture in the oscillation between Western and Eastern gaze considered in connection to the problems of emptiness and meditation drawn from Zen religious beliefs. In discussing his installations there is special stress to reconstruct his inner-insight into the subject of seeing and watching inscribed in a closed-circuit of the communication network.
Monika Sułkowska (red.) Frazeologia somatyczna w ćwiczeniach.
Authors: Grabowska Monika , Ucherek Witold
Published: April 2021

Katowice: Wydawnictwo Uniwersytetu Śląskiego, 2019, t. 1: A. Dolata-Zaród, D. Topa-Bryniarska, Język francuski, t. 2: A. Gwiazdowska, Z. Lamba, Język hiszpański, t. 3: L. Marcol-Cacoń, A. Pastucha-Blin, Język włoski.
Le soi de l’apprenant d’une langue étrangère : adaptation de certaines théories psychologiques en didactique de langues
Authors: Pudo Dorota
Published: April 2021

As an interdisciplinary science, SLA studies are receptive to ideas formulated in other disciplines. Although the relevance of psychology for SLA is often underestimated, its influence has recently grown with the advent of neurosciences and the increased interest in learner variables. One f concept from psychology that is potentially interesting is theories of the self, some of which have recently been adapted into research on foreign language learner motivation. In this article, we examine two particular psychological concepts (possible selves and self-discrepancy) as sources of an influential L2 motivation model – Dörnyei’s L2 Motivational Self System – which is very little debated in French SLA literature. We outline the main points of the three theories, analyse them and try to assess the adaptation process. As in any case of transfer between disciplines, the source theories are altered, but the result has proven a meaningful and enriching addition to studies of L2 motivation.
Kolokacje pronominalne jako źródło tożsamościowych odniesień (na materiale relacji świadków powstania warszawskiego)
Authors: Duda Beata , Ficek Ewa
Published: April 2021

The authors of the article present the results of (quantitative and qualitative) research on narrative interviews from the Oral History Archive – more precisely: memories of the Warsaw Uprising witnesses (its active participants). The main subject of the analyses, which align with the trends of reflections on the phenomenon of studies on social archives and follow the premises of memory linguistics, are the elements of the lexical level, i.e. collocations of the possessive pronouns mój, nasz (my, ours). In the discourse on the events of August 1944, they can be considered to be some of the significant determinants of individual and/or collective identities of the subjects. The search for answers to the questions about how the identity of the Warsaw Uprising participants is revealed at the level of selected biographical narrations, whatelements dominate there and how it is determined, allows for drawing some conclusions, including the final one: despite the expected predominance of individual identity (and personal views of the past), the examined relationships show a strong expansion of the sense of community which is evident even in the areas that fall within the domain of individual memory.