bluuebunny/crossref_metadata_2025 huggingface dataset:
Biomimetic Hydrogels in the Study of Cancer Mechanobiology: Overview, Biomedical Applications, and Future Perspectives
Authors: Sahan Ayse Z. , Baday Murat , Patel Chirag B.
Published: August 2022

Hydrogels are biocompatible polymers that are tunable to the system under study, allowing them to be widely used in medicine, bioprinting, tissue engineering, and biomechanics. Hydrogels are used to mimic the three-dimensional microenvironment of tissues, which is essential to understanding cell–cell interactions and intracellular signaling pathways (e.g., proliferation, apoptosis, growth, and survival). Emerging evidence suggests that the malignant properties of cancer cells depend on mechanical cues that arise from changes in their microenvironment. These mechanobiological cues include stiffness, shear stress, and pressure, and have an impact on cancer proliferation and invasion. The hydrogels can be tuned to simulate these mechanobiological tissue properties. Although interest in and research on the biomedical applications of hydrogels has increased in the past 25 years, there is still much to learn about the development of biomimetic hydrogels and their potential applications in biomedical and clinical settings. This review highlights the application of hydrogels in developing pre-clinical cancer models and their potential for translation to human disease with a focus on reviewing the utility of such models in studying glioblastoma progression.
Laboratory-Controlled Experiments Reveal Microbial Community Shifts during Sediment Resuspension Events
Authors: DesRosiers Alexis , Gassama Nathalie , Grosbois Cécile , Lazar Cassandre Sara
Published: August 2022

In freshwater ecosystems, dynamic hydraulic events (floods or dam maintenance) lead to sediment resuspension and mixing with waters of different composition. Microbial communities living in the sediments play a major role in these leaching events, contributing to organic matter degradation and the release of trace elements. However, the dynamics of community diversity are seldom studied in the context of ecological studies. Therefore, we carried out laboratory-induced leaching experiments, using sediments from the Villerest dam reservoir (Villerest, France). To assess whole microbial community diversity, we sequenced the archaeal and bacterial 16S rRNA genes using Illumina MiSeq. Our results suggest that the degree of dissolved oxygen found in the water during these resuspension episodes influenced community dynamics, with anoxic waters leading to drastic shifts in sedimentary communities compared to oxic waters. Furthermore, the release of microbial cells from sediments to the water column were more favorable to water colonization when events were caused by oxic waters. Most of the bacteria found in the sediments were chemoorganotrophs and most of the archaea were methanogens. Methylotrophic, as well as archaeal, and bacterial chemoorganotrophs were detected in the leachate samples. These results also show that organic matter degradation occurred, likely participating in carbonate dissolution and the release of trace elements during freshwater resuspension events.
Scale Influence on Qualitative–Quantitative Geodiversity Assessments for the Geosite Recognition of Western Samoa
Authors: Zakharovskyi Vladyslav , Németh Károly
Published: August 2022

Spatial scale in modeling is one of the most important aspects of any kind of assessment. This study utilized previously studied assessments of geodiversity through a qualitative–quantitative methodology for geosite recognition. Our methodology was developed based on geodiversity as a complex description of all elements of abiotic nature and processes, influencing it. Based on this definition, geodiversity can be divided into main elements: geology and geomorphology, creating a core of abiotic nature; and additional elements including hydrology, climate, and human influences. We include this description of geodiversity here to emphasize the data which were used in the assessment. The methodology was based on an evaluation system, subject to improvements informed by previous research, and map-based models showing the area of spreading of calculated elements. Except for additional changes in the assessment, this article primarily addresses the problem of scale, by comparing two different methods of scale in the research: grid and non-grid. Grid types of assessment are considered a widely useable method, requiring definitions of areas of research with a potential variety of polygons, and calculating elements inside the cell and applying values to each cell. In contrast, non-grid assessment utilizes the natural borders of all elements (e.g., map view pattern of geological formations), and including them in calculations. The union of layers from different elements creates shapes which highlight regions with the highest values. Hence, the goal of this article is to demonstrate differences between grid and non-grid assessments of geodiversity in Western Samoa. In our results, we compare the methods and emphasize specific tasks most suitable for each method.
Initial Accretion in Hamelin Pool Microbialites: The Role of Entophysalis in Precipitation of Microbial Micrite
Authors: Vitek Brooke E. , Suosaari Erica P. , Stolz John F. , Oehlert Amanda M. , Reid R. Pamela
Published: August 2022

One of the largest assemblages of living marine microbialites, with shapes and sizes analogous to ancient structures, is found along the margins of Hamelin Pool, Shark Bay, Western Australia. An investigation of microbial mats on the surfaces of these structures using petrographic analysis, light, and scanning electron microscopy identified the in situ precipitation of micrite as an important accretion mechanism in all major mat types (pustular, smooth, and colloform). Within each mat type, peloidal micrite, composed of nano-bulbous spheres to tabular and rod-shaped crystals, was closely linked with cells of the coccoid cyanobacterium Entophysalis, and microtextures of the micrite reflected the size and distribution of Entophysalis colonies. In pustular surface mats, where large colonies of Entophysalis were common, large clots of micrite were distributed randomly throughout the mat. In contrast, in smooth and colloform mats, where smaller colonies of Entophysalis were distributed along horizons, micrite formed fine laminae. In all surface mat types, micrite associated with Entophysalis had a characteristic honeycomb appearance, resulting from cell and/or colony entombment. These findings redefine our understanding of microbialite accretion in Hamelin Pool, recognizing the importance of microbial micrite in microbialite growth and showing that coccoid cyanobacteria are capable of building laminated structures. Moreover, Entophysalis, the dominant visible microbe associated with the precipitation of micrite in Hamelin Pool, has a lineage to Eoentophysalis, found throughout early and middle Proterozoic microbialites assemblages. These findings reinforce the importance of Hamelin Pool as a window to the past.
Experiences, Perceptions, and Coping Patterns of Emergency Department Nurses with Occupational Stressors in Saudi Arabian Hospitals: Mixed-Method Study
Authors: Alruwaili Majed M. , Abuadas Fuad H. , Maude Phillip , Ross Alistair
Published: August 2022

Extended working hours, a complicated workplace environment, and engagement in numerous physical and psychological stressors have been associated with the stressful nature of the nursing profession. Only a few studies have provided some insight into workplace stress and coping strategies adopted by nurses in Saudi Arabia and neighboring countries. Therefore, this study utilized a mixed-method design to explore the numerous factors that lead to stress among emergency nurses, their experience and perception of stress, and the coping mechanisms they find useful. A survey containing four domains and 86 items was adapted, pilot tested, and validated. The quantitative phase recruited 296 nurses who returned completed questionnaires, and then 21 nurses were interviewed for the qualitative phase. In total, 89.5% (n = 265) of the participants were female, 51% (n = 151) were aged 20–29 years, 83% (n = 246) were non-Saudi nationals, 49% (n = 145) were married, and 82% (n = 245) had a bachelor’s degree. The most common causes of occupational stress were work overload, personnel shortages, and inadequate pay. The qualitative phase data revealed five primary themes, including increased workload, rising living costs despite equal compensation, and staff shortages as main stressors. In addition, the study found that praying and spending quality time with friends are the primary coping techniques among nurses. The study results contribute to a better understanding of nurses’ working conditions in the emergency department. Additionally, they may contribute to the development of policies and practice reforms to improve Saudi nurses’ well-being, health, and overall work experience.
The Mediating Role of Psychological Resilience in the Relationship between Emotional Reactivity, Intolerance of Uncertainty and Psychological Maladjustment in Children Receiving Orthodontic Treatment
Authors: Durna Nurhan B. , Durna Doğan , Seçer İsmail
Published: August 2022

The aim of this research was to examine the various psychological characteristics that affect psychological maladjustment in children undergoing orthodontic treatment. In this context, the predictive and mediating relationships between emotional reactivity, intolerance of uncertainty, psychological resilience and psychological maladjustment were considered. The study was conducted cross-sectionally with 543 children and adolescents aged 10–18 years, who were being treated at a state university orthodontic clinic in Turkey. Standardized measurement tools (The Emotional Reactivity Scale, Intolerance of Uncertainty Scale, Brief Resilience Scale and Depression Anxiety Stress Scale) and online data collection processes were used in the data collection process. The findings show that emotional reactivity and intolerance of uncertainty pose a risk for psychological maladjustment in children and adolescents receiving orthodontic treatment, but psychological resilience has a protective function against this risk (p < 0.001). It is suggested that these findings may contribute to the expansion of pediatric dentists’ perspectives on the secondary outcomes of orthodontic treatment practices.
Assessing the Effect of Curcumin on the Oral Mucosal Cytomorphometry and Candidal Species Specificity in Tobacco Users: A Pilot Study
Authors: Mehta Prishita , Bhavasar Rashmi , Ajith Namratha A. , Bhavsar Rahul P. , Bahammam Maha A. , Bakri Mohammed Mousa H. , Alzahrani Khalid J. , Alghamdi Ahmad A. , Halawani Ibrahim F. , Bhandi Shilpa , Raj A. Thirumal , Patil Shankargouda
Published: August 2022

Objectives: Tobacco consumption is of major concern for public health. Compromised oral hygiene accentuated by tobacco leads to alteration in the oral mucosa and microbiome, including Candida, and its species can be identified rapidly using CHROMagar. Curcumin, a naturally available compound possesses antioxidant, anti-inflammatory, anti-microbial, anti-carcinogenic, anti-fungal, and immunomodulatory properties. Hence, a comprehensive study was planned. Aim: To evaluate and compare cytomorphometric analysis and Candida colonization and speciation in tobacco users before and after the use of curcumin gel. Materials and Methods: The study comprised a total of 120 participants (the study (tobacco habit) group, n = 60 and control (healthy) group, n = 60). The intervention was the application of curcumin gel over the lesion area three times daily for 2 months. All participants’ oral health status was assessed, followed by cytomorphometric analysis and Candida colonization and speciation using CHROMagar. Results: Cytomorphometric analysis showed statistically significant differences in the control and study group for cell diameter (CD), nuclear diameter (ND), CD:ND ratio, and micronuclei (p = 0.0001). Candida colonization had a significantly higher number of colonies in the habit group when compared to the control group. Candida tropicalis was predominant in the study group, whereas Candida albicans was predominant in the control group. In the study group, after intervention with curcumin, a statistically significant difference was seen in nuclear diameter, CD:ND ratio, and micronuclei. There was a reduction in the number of Candida colonies, and Candida albicans was the predominant species observed in the study group after the intervention of curcumin and discontinuation of habit. Conclusion: Curcumin was found to reduce the number of micronuclei and also decreased Candida colonization, along with the discontinuation of habit in tobacco users.
Optimization of Intervention Strategies for Masonry Buildings Based on CLT Components
Authors: Salvalaggio Matteo , Valluzzi Maria Rosa
Published: August 2022

Unreinforced masonry has been for centuries one of the most widespread constructive techniques for both massive structures and civil buildings (e.g., palaces, hospitals, houses), for the most still standing nowadays. Their future conservation relies on (i) their protection from main natural threats (e.g., earthquakes) and (ii) updating to current functionality and hygrothermal standards. In the former framework, existing masonry buildings proved to have some intrinsic vulnerabilities, depending on composition (units and binder) and structural typologies. Based on experience gathered from seismic events, various retrofitting techniques have been proposed. In such a context, the use of cross-laminated timber (CLT) components is a very promising solution, in terms of compatibility with built heritage and integration of seismic and hygrothermal performances. This paper aims at improving the knowledge of the structural performances of compound timber–masonry interventions by numerical simulations carried out at (i) pier scale and (ii) building full scale via finite element modeling and nonlinear static analyses (pushover). First, a coupled timber–masonry wall was simulated and underwent sensitivity analyses with the properties of both components varying; then, the optimized solution was applied to a case study to assess the intervention benefits, and the results were also cross-checked with those of more traditional interventions (e.g., grout injections).
Advances in Modelling of Rainfall Fields
Authors: Luca Davide , Petroselli Andrea
Published: August 2022

Rainfall is the main input for all hydrological models, such as rainfall–runoff models and the forecasting of landslides triggered by precipitation, with its comprehension being clearly essential for effective water resource management as well [...]
The Monkeypox Pandemic as a Worldwide Emergence: Much Ado?
Authors: Ciccozzi Massimo , Petrosillo Nicola
Published: August 2022

The dramatic emergence of SARS-CoV-2 infection worldwide opened the Pandora’s box of fears and frights for new emerging infections [...]
Occupational Exposures and Esophageal Cancer: Prog Study
Authors: Gressier Annabelle , Gourier Greta , Metges Jean-Philippe , Dewitte Jean-Dominique , Loddé Brice , Lucas David
Published: August 2022

Esophageal cancer is the sixth most common cause of cancer death worldwide. In France, Brittany is one of the regions most seriously affected. This increased incidence is usually linked to high rates of alcohol overconsumption and smoking, established risk factors for esophageal cancer, but the region has special occupational exposures. We aim to describe the occupational exposures of patients with esophageal cancer. Between June and October 2020, we conducted a monocentric descriptive study in a French Teaching Hospital and identified 37 eligible patients. We gathered data through a systematic individual interview for each participant and by an analysis of their medical file. We were able to include 36 patients; most were men (n = 27, 75.0%) and smokers (n = 25, 69.4%), 21 (58.3%) presented an adenocarcinoma esophageal cancer, 13 (36.1%) a squamous cell cancer, and 2 other types. On occupational exposure, patients declared respectively high exposure by manipulating asbestos materials for 11 (30.6%) patients, regularly in contact with benzene by handling fuel in 7 cases (19.4%), chlorinated solvents in 4 cases (11.1%), pesticides in 4 cases, and ionizing radiation exposure in 3 patients (8.3%). Our findings support the creation of a large-scale study to explore the impact of occupational exposures, particularly exposure to asbestos and hydrocarbons.
Body Checking and Body Image Avoidance as Partial Mediators of the Relationship between Internalized Weight Bias and Body Dissatisfaction
Authors: Bennett Brooke L. , Wagner Allison F. , Latner Janet D.
Published: August 2022

Internalized weight bias is associated with body image disturbances and the development of disordered eating. The association between weight bias internalization and body dissatisfaction has proven difficult to disrupt. In order to develop more effective interventions, we must identify the behavioral targets which account for this robust association. The present study sought to examine whether body checking and body image avoidance mediate the relationship between weight bias internalization and body dissatisfaction. In total, 279 female undergraduates (Mage = 20.13, SD = 4.10) were administered a battery of survey measures. Results demonstrated that body checking partially mediates the relationship between weight bias internalization and body dissatisfaction, Z = 7.42, p < 0.001. Body image avoidance was also found to partially mediate the relationship between weight bias internalization and body dissatisfaction, Z = 70.03, p < 0.001. These findings suggest that body checking and body image avoidance may both partially account for the association between weight bias internalization and body dissatisfaction. These findings extend the existing literature on weight bias internalization by highlighting two behavioral targets for prevention and intervention efforts. Understanding these relationships has important implications for both reducing weight bias internalization and improving body dissatisfaction.
COVID-19 Pandemic and Remote Consultations in Children: A Bibliometric Analysis
Authors: Camoni Nicole , Cirio Silvia , Salerno Claudia , Balian Araxi , Bruni Giulia , D’Avola Valeria , Cagetti Maria Grazia
Published: August 2022

Telemedicine is becoming a standard method of consultation, and the COVID-19 pandemic has increased its need. Telemedicine is suitable for non-communicable diseases (NCDs) in the pediatric population, as these are chronic conditions that affect many children worldwide. The aim of this study was to analyze the bibliometric parameters of publications on the use of telemedicine for the most common NCDs in children before and after the COVID-19 pandemic. Following the electronic search, 585 records were selected. “Metabolic diseases” was the most frequent topic before and after the pandemic, accounting for 34.76% in 2017–2019 and 33.97% in 2020–2022. The average IF of the journals from which records were retrieved was 5.46 ± 4.62 before and 4.58 ± 2.82 after the pandemic, with no significant variation. The number of citations per reference averaged 14.71 ± 17.16 in 2017–2019 (95% CI: 12.07; 17.36) and 5.54 ± 13.71 in 2020–2022 (95% CI: 4.23; 6.86). Asthma, metabolic diseases, and neurodevelopmental disorders were the most explored topics. A relevant finding concerns the increasing number of observational studies after the pandemic, with a reduction of the interventional studies. The latter type of study should be recommended as it can increase the evaluation of new strategies for the management of NCDs.
Impact of Body Mass Index on Muscle Strength, Thicknesses, and Fiber Composition in Young Women
Authors: Sung Eun-Sook , Han Ahreum , Hinrichs Timo , Vorgerd Matthias , Platen Petra
Published: August 2022

High body mass index (BMI) may influence muscle strength, muscle thickness (Mtk), and fiber composition. We evaluated these parameters in 31 and 27 women grouped in non-oral contraceptive (non-OC) groups and OC groups, respectively, and further divided them into groups based on BMI: BMIlow, BMInorm, and BMIhigh. Maximum isometric force (Fmax), Mtk, and the relative percentage of muscle fiber composition (%) were examined in both groups. Fmax and Mtk values were significantly greater in the BMIhigh than the BMIlow within the OC group. However, there was no significant difference in the non-OC group. BMIlow and BMInorm groups showed a difference in the distribution of muscle fiber types 1 and 2 with almost the same proportions in both non-OC and OC groups. However, the BMIhigh group showed a difference in the distribution of muscle fiber types 1 and 2, with type 1 about 18.76% higher in the non-OC group. Contrastively, type 2 was about 34.35% higher in the OC group. In this study, we found that there was a significant difference in Fmax and Mtk according to the BMI level in the OC group, but no significant difference was found in the non-OC group. Moreover, the distribution of type 2 muscle fibers tended to be higher in the OC group of BMIhigh, although the sample size was small. Therefore, although no significant difference of Fmax and Mtk was found according to BMI level in the non-OC group in this study, the increase in BMI level appeared to be more associative of muscle strength in the OC group. Based on the present results, future studies are needed that consider the BMI level as well as the presence or absence of OC in future research about women’s muscle strength.
The Role of Facebook® in Promoting a Physically Active Lifestyle: A Systematic Review and Meta-Analysis
Authors: Duregon Federica , Bullo Valentina , Di Blasio Andrea , Cugusi Lucia , Pizzichemi Martina , Sciusco Salvatore , Viscioni Gianluca , Cruz-Diaz David , Bocalini Danilo Sales , Bortoletto Alessandro , Favro Francesco , Alberton Cristine Lima , Gobbo Stefano , Bergamin Marco
Published: August 2022

Background: it is well known in literature that sedentary lifestyle contributes to worsening people’s health. This issue highlights the need for effective interventions to promote an active lifestyle. Research suggested multilevel intervention strategies to promote adherence to recommended physical activity levels, including the use of social networks that may simplify access to health notions. Being Facebook® the most extensive worldwide social network, this document aimed to analyze the current body of evidence on the role of Facebook® in the promotion of physical activity. Methods: eighteen manuscripts were considered eligible for this systematic review, and it was performed a meta-analysis (PRISMA guidelines) for overall physical activity parameters in eleven out of eighteen studies. Results: significant improvements were detected in the total amount of physical activity. In parallel, an increase in other parameters, such as cardiovascular, body composition, and social support, were found. The aerobic training, with supervised and tailored modalities, showed more considerable improvements. Conclusions: this study showed that Facebook® might be considered a feasible and accessible approach to promoting regular exercise practice and achieving health benefits indicators. Future research on the cross-link between physical activity and social network management could also focus on strength training to verify if a more structured intervention would show an effect.
Measurement Invariance of the WHO-5 Well-Being Index: Evidence from 15 European Countries
Authors: Cosma Alina , Költő András , Chzhen Yekaterina , Kleszczewska Dorota , Kalman Michal , Martin Gina
Published: August 2022

(1) Background: The World Health Organization (WHO)-5 Well-Being Index has been used in many epidemiological studies to assess adolescent mental well-being. However, cross-country comparisons of this instrument among adolescents are scarce and, so far, no good-fitting, common invariant measurement model across countries has been reported. The present study aims to evaluate and establish a version of the WHO-5 Well-Being Index that allows for a valid cross-country comparison of adolescent self-reported mental well-being. (2) Methods: Using data from the 2018 Health Behaviour in School-aged Children study, we evaluated the measurement model and measurement invariance of the five items of the WHO-5 Well-Being Index. We used nationally representative samples of 11-, 13-, and 15-year-old adolescents (N = 74,071) from fifteen countries and regions in Europe. Measurement invariance of the WHO-5 was assessed using a series (country, gender, and age) of multi-group confirmatory factor analyses. In addition, we evaluated the convergent validity of the measure by testing its correlations with psychosomatic complaints, life satisfaction, and self-rated health. (3) Results: We found that WHO-5 does not show good psychometric properties or good measurement invariance fit. However, by excluding the first item of the scale (“I have felt cheerful and in good spirits”), the WHO-4, consisting of the other four original items, had good psychometric properties, and demonstrated good suitability for cross-national comparisons (as well as age and gender) in adolescent mental well-being. (4) Conclusions: The present study introduces the WHO-4—a revised version of the WHO-5—, that allows for a valid comparison of mental well-being across fifteen countries and regions in Europe. The WHO-4 proved to be a reliable and valid instrument to assess mental well-being in the adolescent population.
Health as Battlefield: News and Misinformation in the Early Stage of COVID-19 Outbreak
Authors: Liu Qian , Yang Fan
Published: August 2022

From the epidemic center in Wuhan to the entirety of China, with the growing infected population, people are seeking and processing health-related information both online and from traditional media outlets such as newspapers. Online misinformation regarding COVID-19 has been influencing a wide range of readers demonstrating general citizens’ virus-related concerns, while press media have been actively participating in health communication in an attempt to build up a robust, harmonious, and healthy environment. Via a comparison between the news data with the misinformation data during the early stage of the COVID-19 pandemic, from 1 January 2020 to 20 February 2020, we conducted an LDA topic-modeling analysis and a sentiment analysis. This study sheds light on the nature of people’s methods of health communication with online and press media sources during the early period of the pandemic crisis and provides possible readable explanations for the driving force of misinformation and the emotional changes experienced by the public.
Sleep Disturbances and Health Consequences Induced by the Specificity of Nurses’ Work
Authors: Knap Małgorzata , Maciąg Dorota , Trzeciak-Bereza Edyta , Knap Bartosz , Czop Marcin , Krupa Sabina
Published: August 2022

Introduction: Nursing staff working in a shift or night system are exposed to sleep disorders, which has a direct impact on the emergence of dangerous health consequences for them. Melatonin secretion is abnormal at night and the circadian rhythm is disturbed. The aim of the study was to assess the occurrence of sleep disorders and their consequences for the body in a group of representative nursing staff working in a shift and night system. Participants: The study was conducted among 126 nurses who are generally healthy, employed in health care facilities in the Małopolskie voivodship. Methods: The Athens Insomnia Scale consisting of 8 test items was used to obtain research material: falling asleep, waking up at night, waking up in the morning, total sleep time, sleep quality, well-being the next day, mental and physical fitness the next day, and sleepiness during the next day. As well as an original questionnaire. Results: The research showed significant negative consequences of shift work on the health of health-care workers. The subjects noticed symptoms related to the nervous system, such as increased nervous tension 53%, lack of patience in 62% of all respondents. As many as 85% pointed to the negative impact of shift work on their family life, 82% of all respondents on social life and 56% of all respondents on sex life. The other variables were not confirmed. Conclusions: Symptoms of insomnia are common among night-work nurses.
Assessment of Magnetic Nanomaterials for Municipality Wastewater Treatment Using Biochemical Methane Potential (BMP) Tests
Authors: Amo-Duodu Gloria , Tetteh Emmanuel Kweinor , Rathilal Sudesh , Chollom Martha Noro
Published: August 2022

Wastewater as a substrate potential for producing renewable energy in the form of biogas is gaining global attention. Herein, nanomaterials can be utilised as a nutrient source for microorganisms for anaerobic digestion activity. Therefore, this study explored the impact of seven different magnetic nanomaterials (MNMs) on the anaerobic digestion of wastewater via biochemical methane potential (BMP) tests for biogas production. The BMP assay was carried out with eight bioreactors, where each was charged with 50% wastewater and 30% activated sludge, leaving a headspace of 20%. Aside the control bioreactor, the other seven (7) bioreactors were dosed with 1.5 g of MNMs. This was operated under anaerobic conditions at a mesophilic temperature of 35 °C for 31 days. At the degree of 80% degradation of contaminants, the results that showed bioreactors charged with 1.5 g MNMs of TiO2 photocatalyst composites were more effective than those constituting metallic composites, whereas the control achieved 65% degradation. Additionally, the bioreactor with magnetite (Fe3O4) produced the highest cumulative biogas of 1172 mL/day. Kinetically, the modified Gompertz model favoured the cumulative biogas data obtained with a significant regression coefficient (R2) close to one.
EsReflux Protocol: Epidemiological Study of Heartburn and Reflux-like Symptoms in Spanish Community Pharmacies
Authors: López-Pintor Elsa , Puig-Moltó María , Lumbreras Blanca
Published: August 2022

(1) Background: Heartburn and reflux discomfort are frequent reasons for consultation at the community pharmacy. To facilitate the assistance work of the community pharmacist and its coordination between different levels of care, a group of experts in Community Pharmacy, Primary Care, and Gastroenterology have recently worked on an algorithm to manage these symptoms in the community pharmacy (Professional Pharmaceutical Service). The objective of this study is to analyze the clinical and sociodemographic characteristics of patients with heartburn and/or reflux-like symptoms who go to a community pharmacy, and to evaluate the clinical and humanistic results after the implementation of a Professional Pharmaceutical Service. (2) Methods: A pre-post study will be carried out to evaluate clinical and humanistic results after the implementation of a Professional Pharmaceutical Service. We will include 1200 patients who ask for advice or get a non-prescription medication due to acid and/or reflux symptoms in 240 Spanish pharmacies. Clinical data will be collected at baseline and 15 days after the pharmaceutical intervention. The GERD Impact Scale (GIS) questionnaire will be applied to assess changes in heartburn/reflux-like symptoms and quality of life after the intervention.
Impression Management on Instagram and Unethical Behavior: The Role of Gender and Social Media Fatigue
Authors: Al-Shatti Esraa , Ohana Marc , Odou Philippe , Zaitouni Michel
Published: August 2022

Impression management (IM) concerns can lead to significant psychological consequences, potentially engendering unethical behavior. Therefore, adopting the stressor–strain–outcome framework, this study explores the effects of IM concerns on unethical behavior through wellbeing, and whether IM on social media (i.e., Instagram) triggers fatigue and results in unethical behavior at work. The findings of two empirical studies (n = 480 and n = 299) in different settings (Kuwait and the UK) suggest that women experience higher effects from IM concerns compared with men in Kuwait, while no gender differences are found in the UK. The results also confirm that impression management on social media platforms triggers fatigue, in turn increasing unethical behavior at work. This study contributes to the IM literature by capturing the effect of Instagram activities on workplace behavior.
Family Needs Checklist: Development of a Mobile Application for Parents with Children to Assess the Risk for Child Maltreatment
Authors: Rantanen Heidi , Nieminen Irja , Kaunonen Marja , Jouet Emmanuelle , Zabłocka-Żytka Lidia , Viganò Giovanni , Crocamo Cristina , Schecke Henrike , Zlatkute Giedre , Paavilainen Eija
Published: August 2022

Child maltreatment (CM) has been enormously studied. However, a preventive practice still requires comprehensive and effective instruments to assess the risks for CM in a family context. The aim of this study is to describe the development process of an evidence-based CM risk assessment instrument (Family Needs Checklist, FNC) for primary prevention online utilization. This article reports the development process of the checklist and its mobile application, consisting of a systematic literature review, identification of known risk factors using the content analysis method, and generation of the checklist, including a multidisciplinary group in the design and feedback. As a result, a comprehensive and compact checklist was developed to be used by parents or caregivers as a self-referral instrument with an option to be used with professionals as a basis for joint conversations. The FNC consists of parental, family-, and child-related risk factors. Based on the international evidence, the online application consists of knowledge about different CM types, information about risk factors and protective factors as well as recommendations and guidance to support services. The FNC is based on robust evidence on known risk factors causing CM in families. It can be used for primary prevention utilization in the general population.
Life Cycle Assessment on Agricultural Production: A Mini Review on Methodology, Application, and Challenges
Authors: Fan Jianling , Liu Cuiying , Xie Jianan , Han Lu , Zhang Chuanhong , Guo Dengwei , Niu Junzhao , Jin Hao , McConkey Brian G.
Published: August 2022

Agricultural Life Cycle Assessment (LCA) is an effective tool for the quantitative evaluation and analysis of agricultural materials production and operation activities in various stages of the agricultural system. Based on the concept of life cycle, it comprehensively summarizes the impact of agriculture on the environment, which is an effective tool to promote the sustainability and green development of agriculture. In recent years, agricultural LCA has been widely used in the agroecosystem for resource and environmental impacts analysis. However, some challenges still exist in agricultural LCA, i.e., the environmental impact assessment index system needs to be improved; its application in different production mode is limited; and combination research with other models needs more attention. This paper discusses the above-mentioned challenges and recommends research priorities for both scientific development and improvements in practical implementation. In summary, further research is needed to construct a regional heterogeneity database and develop innovated methodologies to develop more meaningful functional units for agricultural products to complement LCA by other models. These efforts will make agricultural LCA more robust and effective in environmental impacts assessment to support decision making from individual farm to regional or (inter)national for the sustainable future of agriculture.
Work as a Social Determinant of Racial Health Inequalities
Authors: Montgomery Shannon C. , Grzywacz Joseph G.
Published: August 2022

Interdisciplinary research posits that work is a social determinant of health contributing to racial inequalities in death, disease, and well-being amongst Black individuals in the United States. This study aims to advance research by integrating two theoretical frameworks (Warr’s Vitamin Model and Assari’s “differential exposure” and “differential gain” mechanisms) to investigate the role of work in eudemonic well-being. We included a nationally representative sample of adults who participated in the Midlife in the United States (MIDUS) Refresher and Milwaukee Refresher projects in 2011–2014, alongside corresponding occupational information (O*NET 17.0). The results of this study indicated that three of nine studied job characteristics systematically differ by race. We found evidence of differential gain by race on psychological well-being. Job characteristics had either benign or negative associations with well-being among Black individuals but consistently positive associations with well-being among non-Black individuals. In contrast to Warr’s Vitamin Model, we found little evidence of curvilinear health effects of job characteristics (only 5.5% were statistically significant). Finally, it was found that advanced educational attainment benefited multiple dimensions of well-being among Black individuals but had benign or negative implications for non-Black individuals, after controlling for demographics. Overall, the results highlight racial inequalities in eudemonic well-being because Black individuals face challenges in obtaining jobs that are beneficial to well-being. Collectively, the results reinforce the idea that work is a social determinant of health.
Worker Perspectives on COVID-19 Risks: A Qualitative Study of Latino Construction Workers in Oakland, California
Authors: Meza Erika , Giglio Leslie , Franco Ana O. , Rodriguez Elizabeth , Stock Laura , Balmes John , Torres Jacqueline M. , Fernandez Alicia
Published: August 2022

Latino construction workers in the U.S. have faced a disproportionate risk for COVID-19 infection in the workplace. Prior studies have focused on quantifying workplace risk for COVID-19 infection; few have captured workers’ experiences and perspectives. This study describes COVID-19-related workplace risks from the perspectives of Latino construction workers. We conducted a qualitative study using semi-structured phone interviews with Latino construction workers from the Fruitvale District of Oakland, California. Twenty individuals were interviewed from December 2020 to March 2021. Nearly all participants (19/20) were Spanish-speaking men; mean age 42.6 years. The majority were low-income and over one-third did not have health insurance. Participants worked in varied construction-related jobs ranging from demolition to office work; additionally, four were day laborers, and three belonged to a labor union. We identified four major themes with public health policy and workplace safety implications: (1) Major concern about the risk of SARS-CoV-2 infection for family health and economic wellbeing; (2) Clarity about mask use and social distancing but not disclosure; (3) Variability in access to additional resources provided by employers; and (4) Uncertainty around structural support for SARS-CoV-2 quarantine/isolation. Our findings provide further evidence from workers’ own perspectives of the major gaps experienced during the pandemic in workplace protections and resources.
In the COVID-19 Era, Effects of Job Stress, Coping Strategies, Meaning in Life and Resilience on Psychological Well-Being of Women Workers in the Service Sector
Authors: Kim Hee-Kyung
Published: August 2022

The purpose of this study is to analyze the factors affecting the psychological well-being by using variables of job stress, coping strategies, meaning of life, and resilience to improve the quality of working life during COVID-19. The subjects were 135 adult women working for banks. Data were collected by having the subjects fill out a paper-and-pencil questionnaire, and analyzed through t-test, ANOVA, Pearson’s correlation coefficients, and multiple regression analysis. The subjects’ psychological well-being showed positive correlations with the social support-seeking coping mechanism (r = 0.33, p < 0.001), problem-solving-focused coping mechanism (r = 0.55, p < 0.001), meaning in life (r = 0.45, p < 0.001), and resilience (r = 0.37, p < 0.001). Psychological well-being showed negative correlations with job stress (r = −0.44, p < 0.001) and avoidance-focused coping mechanism (r = −0.28, p = 0.001). The factors affecting the psychological well-being were problem-solving-focused coping mechanism (β = 0.35, p < 0.001), job role stress (β = −0.24, p < 0.001), meaning inlife (β = 0.29, p < 0.001), avoidance-focused coping mechanism (β = −0.23, p < 0.001), and resilience (β = 0.15, p = 0.023). It is necessary to formalize psychological intervention to induce the improvement of the quality of work life by increasing the psychological well-being of working women during the COVID-19 pandemic. It is suggested that intervention is made in consideration of variables identified as influencing factors to increase the psychological well-being of women workers.
Association between Tongue Pressure and Jaw-Opening Force in Older Adults
Authors: Namiki Chizuru , Hara Koji , Yanagida Ryosuke , Nakagawa Kazuharu , Yamaguchi Kohei , Okumura Takuma , Tamai Tomoe , Kurosawa Yukiko , Komatsu Tomoko , Tohara Haruka
Published: August 2022

Tongue pressure (TP) is used to assess tongue muscle strength and is related to function and frailty. While performing TP, it is necessary to elevate the tongue and oral floor by contracting the suprahyoid muscles. However, the association between TP and suprahyoid muscle strength remains unclear. Accordingly, this study investigated the relationship between TP and jaw-opening force (JOF), an indicator of suprahyoid muscle strength. This cross-sectional study included 88 independent community-dwelling participants aged ≥65 years. Age, sex, and the number of remaining teeth were recorded. Ultrasonography was used to evaluate the cross-sectional area of the tongue and geniohyoid muscle, as representatives of the suprahyoid muscles. Sarcopenia was diagnosed based on appendicular skeletal muscle mass index, handgrip strength, and gait speed. Multiple regression analysis was performed with TP as the dependent variable. TP was significantly associated with JOF (β = 0.371, p = 0.003). This study revealed that decreased TP was associated with a decline in JOF and suprahyoid muscle mass in older adults. Thus, low TP may be associated with decreased JOF. Prevention of the weakness of the suprahyoid muscles and maintaining TP may also contribute to the prevention of frailty associated with TP.
Assessment of the Radiological Health Risk Due to the 226Ra Content in Drinking Water from the Calabria Region, Southern Italy
Authors: Caridi Francesco , Paladini Giuseppe , Spoto Sebastiano Ettore , Marguccio Santina , D’Agostino Maurizio , Belvedere Alberto , Crupi Vincenza , Venuti Valentina , Majolino Domenico
Published: August 2022

In this article, the authors report experimental results obtained for the assessment of the 226Ra content in 80 drinking water samples from the Calabria region, Southern Italy. The activity concentration, measured with the Perkin Elmer Tricarb 4910 TR Liquid Scintillation Counter (LSC) setup, was compared with the reference values reported in the Italian Legislative Decree 28/2016 in order to evaluate any possible radiological health hazards for the population in terms of 226Ra content due to the ingestion of the investigated drinking water. The obtained results put in evidence that the average 226Ra specific activity is lower than the LSC minimum detectable activity (MDA) in all cases, thus, excluding any radiological risk. They also represent the main reference for the investigated area and can be used as a baseline to extend this investigation to the whole region.
3D Co-Seismic Surface Displacements Measured by DInSAR and MAI of the 2017 Sarpol Zahab Earthquake, Mw7.3
Authors: Ali Randa , Wu Xiyong , Chen Qiang , Elubid Basheer A. , Dafalla Dafalla S. , Kamran Muhammad , Aldoud Abdelmottaleb A.
Published: August 2022

On 12 November 2017, an earthquake occurred in Sarpol Zahab city, located on the Iraq/Iran boundary, with a moment magnitude (Mw) of 7.3. Advanced Land Observing Satellite 2 (ALOS-2) L-band (23.6 cm wavelength) and C-band Sentinel-1A data (ascending and descending) were used to detect the co-seismic displacements maps caused by this earthquake. The ALOS-2 data was utilized to reconstruct the 3D co-seismic displacements maps, as well as estimate the fault-dip and slip distribution along the rupture. The results showed the maximum surface displacement in the north, east, and up directions to be 100, 50, and 100 cm, respectively. The best-fit faulting geometry had a strike of 337.5° and a dip of 11.2° toward the northeast, at a depth of 8 km. The predicted geodetic moment was 1.15 1020 Nm, which corresponds to a magnitude of Mw 7.31. There were two significant slip sources: one in the shallower depth range of 8.5–10 km, with a peak slip of 5 m, and another in the depth range of 10.5–20 km, with a peak slip of 5.3 m. Both controlled the principal deformation signals in geodetic images. The slip was concentrated, along with a strike distance of 20 to 40 km, at a depth of 10 to 20 km. The earthquake was caused by the Zagros Mountains Front Fault (ZMFF), based on the results of 3D co-seismic deformation, inferred slip, preliminary investigation, and interpretation of the mainshock, as well as aftershock distributions.
Prevalence and Factors Associated with Sexual Violence against Children in a Brazilian State
Authors: Pedroso Márcia Regina de Oliveira , Leite Franciéle Marabotti Costa
Published: August 2022

Sexual violence is one of the forms of violence against children worldwide. Understanding its magnitude and its associated factors is essential to promote effective protection policies to childhood. The objective was to verify the prevalence and analyze the factors associated with sexual violence against children in a Brazilian state. This is a cross-sectional study analyzing data from reported cases of violence against children in the state of Espírito Santo, Brazil, between 2011 and 2018. The characteristics of the victim, perpetrator and aggression were studied, and the associations were analyzed using Poisson regression. The frequency of sexual violence was 41.8% and was more prevalent in girls, in the age groups 3 to 5 and 6 to 9 years old, in white ethnicity/color and in the urban area. The offenders were mainly men, known to the victim and occurred mainly in the residence. Sexual violence was the most reported violence among children in Espírito Santo, occurring within their circle of trust, demonstrating the need to provide support for families and to advance public policies to guarantee children’s rights.
Symptom Burden of Children with Cancer and Parental Quality of Life: The Mediating Role of Parental Stress
Authors: Lam Winsome , Li Su-Fang , Yi Yan-Zhi , Ho Ka , Lam Katherine , Leung Doris , Chan Kitty , Ho Jacqueline , Chan Stephen , Wang Hai-Xia , Zhou Li , Yin Yan , Wong Frances
Published: August 2022

Background: The aim of this study was to investigate the association between children’s reported symptom burden and their parents’ quality of life, and whether parents’ perceived stress mediates this relationship. Method: this was a cross-sectional quantitative research study. Convenience sampling was used to recruit 80 pairs of parents and their children with cancer. Advanced statistical methods were used to analyse the mediating effects of parental stress between children’s symptom burden and parents’ quality of life. Results: The results showed that parental stress was the mediator in the relationship between children’s reported symptom burden and their parents’ quality of life. Conclusions: Symptom burden was prevalent in Chinese children with cancer living in the community. Children’s symptom burden is an important factor in predicting parental stress level, which simultaneously and directly lower parents’ quality of life. The evidence in this study enlarges the knowledge base about the mediating effect of parental stress on the association between the symptom burden of children with cancer and their parents’ quality of life. This evidence is crucial in paving the way for the development of interventions that improve the parental quality of life through stress-reduction programs.