bluuebunny/crossref_metadata_2025 huggingface dataset:
Análisis del precio de la manzana mediante un modelo SARIMA
Authors: Ruiz Hernández Jaime Antonio , Barrios Puente Geronimo , Gómez Gómez Alma Alicia
Published: March 2019

El seguimiento y predicción de los precios es una importante herramienta en la toma de decisiones en las actividades productivas. Con base a los datos del precio promedio mensuales de la manzana red delicious a nivel nacional, de enero de 1998 a julio de 2017, publicados por el sistema nacional de información e integración de mercados, con el software Gretlâ. El objetivo de la investigación fue generar información sobre el comportamiento del precio de la manzana mediante un análisis de series de tiempo generándose una predicción para los 12 meses posteriores con un modelo Sarima . Los resultados señalaron que el error relativo para la predicción es 2%, lo cual garantiza pronósticos relativamente buenos, se pronosticó que el precio para julio de 2018 sería $31.99.
Sistema de alerta contra el gusano cogollero Spodoptera frugiperda (J. E. Smith) (Insecta: Lepidoptera: Noctuidae)
Authors: Yáñez López Ricardo , Vázquez Ortega Antonio , Arreguín Centeno José Honorato , Soria Ruíz Jesús , Quijano Carranza Juan Ángel
Published: March 2019

El manejo integrado de plagas se puede entender como un sistema de información que apoya a la toma de decisiones en cuanto al manejo fitosanitario de los cultivos. Este sistema se construye en torno al entendimiento de la dinámica poblacional del organismo plaga en su interacción con el hospedante y el ambiente. En México en el año 2003 se estableció el sistema de alerta fitosanitaria del estado de Guanajuato (SIAFEG), como un instrumento para evaluar el impacto de las principales plagas y enfermedades de algunos cultivos de importancia económica en el estado. En 2010 se iniciaron los estudios para construir el modelo del gusano cogollero, incorporándose al SIAFEG en 2011. Los elementos que se conjuntaron para integrar el sistema de alerta para S. frugiperda fueron: la información de la red de estaciones agrometeorológicas de INIFAP-COFUPRO en Guanajuato, un modelo de simulación dinámica del crecimiento y desarrollo del insecto y datos sobre la dinámica poblacional del insecto. El modelo estima la dinámica poblacional del gusano cogollero. Comparando las estimaciones del modelo con los datos del trampeo de adultos se encontró una relación significativa, lo cual indica que el modelo se puede usar de manera confiable. Aplicado a estudios de largo plazo (2 o más años), el modelo puede ser de gran utilidad para entender las causas de la variación en los niveles de población y de daño a los cultivos de un año a otro.
Transplantasi Hukum Bisnis di Era Globalisasi Tantangan Bagi Indonesia
Authors: Aristeus Syprianus
Published: March 2019

Kebijakan investasi di Indonesia saat ini masih terkendala adanyal peraturan perundang-undangan yang tertinggal dengan ketentuan di bidang investasi. Seiring dengan globalisasi serta keikutsertaan dalam bidang investasi, maka untuk dapat mengantisipasi ketentuan tersebut adalah dengan cara melakukan transplantasi hukum untuk dapat mengisi kekosongan yang terjadi sekarang. Penelitian ini bertujuan untuk mengetahui cara yang terbaik bagi pemerintah Indonesia dalam mengisi kekosongan hukum bisnis saat ini. Penelitian ini merupakan suatu penelitian yuridis normatif, dimana titik berat analisis adalah norma hukum yang terdapat dalam literatur dan peraturan perundang-undangan. Kesimpulan yang dapat disampaikan dari penelitian ini adalah bahwa liberalisasi perdagangan khususnya dalam hukum bisnis telah meluas ke segala komoditas, tidak terkecuali dalam hukum bisnis. Bagi pemerintah Indonesia hal ini membawa dampak yang kurang baik mengingat ketertinggalan peraturan perundang-undangan berdampak pada investasi. Untuk dapat mengatasi hal ini, maka pemerintah dapat melakukan transplantasi hukum, khususnya di bidang hukum bisnis.
Optimalisasi Pelaksanaan Tugas dan Fungsi Lapas Terbuka dalam Proses Asimilasi Narapidana
Authors: Haryono Haryono
Published: March 2019

Salah satu tujuan pelaksanaan pembinaan dalam sistem pemasyarakatan adalah pemulihan hubungan antara narapidana dan masyarakat. Lapas Terbuka merupakan unit strategis dalam rangka mempersiapkan narapidana melaksanakan proses reintegrasi sosial yang berdasarkan konsep community–based correction. Tujuan penelitian ini adalah untuk mendeskripsikan pelaksanaan tugas dan fungsi serta implementasi penempatan narapidana di Lapas Terbuka serta hambatan penempatan narapidana di Lapas Terbuka Nusakambangan. Penelitian ini bersifat deskriptif dengan menggunakan pendekatan mix method. Berdasarkan penelitian yang dilakukan, Lapas Terbuka melaksanakan pembinaan narapidana tahap lanjutan dalam bentuk asimilasi. Pelaksanaan penempatan narapidana di Lapas Terbuka Klas IIB Nusakambangan yang sudah memasuki masa asimilasi sudah sesuai dengan Peraturan Menteri Hukum dan HAM Nomor 3 Tahun 2018 dan Surat Edaran Direktur Jenderal Pemasyarakatan Nomor PAS_PK.01.01.02-100 Tahun 2013. Hambatan penempatan narapidana ke Lapas Terbuka Klas IIB Nusakambangan disebabkan antara lain karena kurangnya minat Narapidana, tingginya narapidana khusus, mind set pegawai serta asimilasi juga dilakukan di Lapas umum.
Peran Pemerintah Daerah dalam Mendorong Potensi Indikasi Geografis (Studi pada Provinsi Kepulauan Riau)
Authors: Lukito Imam
Published: March 2019

Provinsi Kepulauan Riau merupakan salah satu daerah yang belum memiliki produk indikasi geografis terdaftar. Keanekaragaman alam Indonesia memberikan kekayaan produk indikasi geografis, oleh karena itu pemerintah perlu mengambil kebijakan untuk memetakan produk-produk yang berpotensi indikasi geografis. Penelitian  ini  menganalisa permasalahan  terkait  peran  Pemerintah  Daerah Kepulauan Riau dalam mendorong potensi indikasi geografis dan kendala dalam pendaftaran indikasi geografis di Kepulauan Riau. Penelitian ini menggunakan pendekatan kualitatif, bersifat deskriptif analisis. Hasil penelitian menyimpulkan bahwa: pertama, peran pemerintah daerah di Kepulauan Riau sejauh ini masih terbatas pada menginventarisir dan menyampaikan data-data produk yang memiliki potensi untuk didaftarkan kepada Kantor Wilayah Kementerian Hukum dan Hak Asasi Manusia Kepulauan Riau, namun belum ada tindak lanjut untuk melakukan penelitian untuk membuat buku persyaratan; dan kedua, kendala dalam pendaftaran indikasi geografis adalah ketidaktahuan manfaat yang diperoleh dari indikasi geografis, kurangnya kesadaran dan ketidakpahaman akan kewajiban membangun indikasi geografis serta faktor alam seperti daerah pertambangan yang berimbas pada hasil pertanian dan perkebunan serta dominasi wilayah perairan dan laut yang menyebabkan tingkat kesulitan dalam mengukur batas wilayah laut dan iklim di bawah perairan laut sebagai variabel yang dideskripsikan dalam buku persyaratan.
A Measure of Perceived Severity in Organizational Crises: A Multidimensional Scale Development and Validation
Authors: Zhou Ziyuan , Ki Eyun-Jung , Brown Kenon
Published: March 2019

This study proposed a definition of perceived crisis severity and created a valid and reliable scale to measure the construct following Churchill’s scale development procedure. The proposed scale, after rigorous pilot testing and exploratory and confirmatory factor analysis, contains 3 factors with 12 items. This study discusses potential applications of the developed measures and provides future research directions.
Environmental Literacy: An Assessment and Evaluation on the Students of Landscape Architecture in Turkey
Authors: Görmüş Sevgi
Published: March 2019

Environmental literacy approach, in recent years,
become one of the fundamental requirements proposed for a sustainable future in
higher education. Environmental literacy is the total of individual
comprehension, ability, attitude and habits which are constantly in progress
and it is based on that short and long term attitudes and behaviors are
developed by his sustainable communication with other people and biosphere. This
study aims to evaluate the environmental consciousness, knowledge and skills of
the students of landscape architecture in terms of environmental literacy. As
data collection tool was used Environmental Literacy Scale where the knowledge
of students about environmental legislation, knowledge and behaviors is
questioned. The findings reveal that students have a very limited environmental
knowledge and fulfill their environmental responsibilities on an individual
basis in a very restricted area. In this regard, the study, based on the
research results, makes suggestions for training environmentally literate
candidates in professional training of environmental by emphasizing that
students of Landscape Architecture would be of low efficiency in finding
creative solutions for environmental, societal and spatial problems and
producing sustainable landscape since their participation is very limited in
societal and mass activities.
The Educational Potential of Augmented Reality Technology: Experiences of Instructional Designers and Practitioners
Authors: Koçak Ömer , Yılmaz Rabia Meryem , Küçük Sevda , Göktaş Yüksel
Published: March 2019

In this study, the educational potential of the
augmented reality (AR) technology was investigated in the context of the
instructional designers and practitioners' experiences. Within this scope,
intrinsic case study design was used in this study. 42 instructional designers
and 10 practitioners participated in the research. The data were collected
using open-ended questionnaire from instructional designers. Interviews were
held with the practitioners through the semi-structured interview form created
from the open-ended questionnaire. The qualitative data were analyzed with the
content analysis method, using Nvivo 8.0 software. The participants suggested
that AR would be more influential in the educational fields of science education,
social studies, and health education. Among the most important instructional
materials to be developed with AR technology are 3D materials, videos, and
animations. The participants suggested that AR could be useful in the
development of special applications for other fields of education. For example,
AR could be used to create magic books, 3D demonstrations related to different
subjects, and experimental simulations in the field of science education.
Moreover, the participants suggested that AR could provide system design
enhancements to better attract users’ attention, to improve retention, to
increase user motivation, and to “concretize” virtually presented information
by creating a fuller sense of reality in terms of educational. Lastly, in order
to develop an AR application, several points must be considered in the stages
of analysis, design, development, and implementation. We present these points
for consideration in detail. The results obtained in this study can be used to
guide future research studies on AR technology.
Approaches to Clinical Development of Combination Medicines in the Russian Federation and the Eurasian Economic Union in view of the Requirements of the Current Legislation
Authors: Dobrovolskiy A. V.
Published: March 2019

In recent years, there has been an increasing interest in the development of combination medicines (fixed drug combinations) containing two or more active ingredients in a single dosage form. Therefore, there is an urgent need to develop an optimal programme of pre-authorisation clinical trials for combination medicines. The aim of the paper was to summarise modern science-based approaches to clinical development of combination medicines and identify possible ways of their practical implementation, taking into account the requirements of the current legislation. The author reviewed scientific publications devoted to creation of fixed drug combinations and analysed the regulatory documents defining regulatory requirements for pre-authorisation clinical studies of medicines in the Eurasian Economic Union, the Russian Federation, and other countries. Based on the results of the analysis the author described the general regulatory requirements for planning clinical studies of combination medicines for the purpose of their subsequent authorisation in the Russian Federation (via the national procedure) and the Eurasian Economic Union (via the centralized procedure). The pre-authorisation clinical development programme should be designed individually for each combination medicine. The selection of an optimal clinical trial strategy will make it possible to obtain sufficient information on the efficacy and safety of a combination medicine for its subsequent authorisation.
Regulatory Requirements of the European Medicines Agency for Evaluation of Bioequivalence of Modified-release Medicinal Products
Authors: Romodanovsky D. P. , Eremenko N. N. , Goryachev D. V.
Published: March 2019

There are no specific requirements and recommendations in the Russian Federation for evaluation of bioequivalence of modified-release medicinal products. Until recently, modified-release products were regulated in a similar manner as immediate-release products, which is unacceptable considering the active ingredient release profile and its pharmacokinetics. The modified release characteristics require a more complex approach to the assessment of equivalence of generic medicines as compared with the reference product. The number of parameters to be assessed and the scope of testing depend on many factors (release mechanism, specific features of the dosage form, linearity of pharmacokinetics, potential for ingredient accumulation, dependence on food intake, dose-dumping effects, and the number of dosage strengths to be registered). The aim of this paper was to develop recommendations for the national procedure of modified-release products authorisation based on the analysis of international regulatory experience in this field. The paper reviews the current European Medicines Agency (EMA) guidelines on evaluation of bioequivalence of generic modified-release dosage forms for oral use that were taken as a basis for the development of Eurasian Economic Union regulations on bioequivalence assessment. The analysis of the above-mentioned documents made it possible to develop recommendations for the national procedure of modified-release products authorisation. In the case of modified-release products for oral use it is recommended to perform bioequivalence studies by comparing the test product with the reference product. The authors developed a procedural algorithm for bioequivalence studies of modified-release medicinal products.
Criteria for Evaluation of Clinical Efficacy of Anticancer Medicines
Authors: Tikhomirova A. V.
Published: March 2019

Criteria for evaluation of clinical efficacy make it possible to assess the risk-benefit ratio of anticancer medicines that patients receive, in particular, for the treatment of solid malignant tumors. A medicine’s efficacy is assessed using special criteria called the endpoints of clinical efficacy, allowing most objective assessment of study results. It was demonstrated that nowadays clinical efficacy of anticancer drugs is assessed using «patient-centered» (overall survival and quality of life) and «tumor-centered» (response to therapy, progression-free survival, disease-free survival) endpoints. «Patient-centered» endpoints make it possible to evaluate the direct clinical benefit of chemotherapy in patients, while «tumor-centered» endpoints allow for evaluation of efficacy at earlier stages, without directly reflecting the clinical benefit. The analysis of the most suitable endpoints with the aim of making them interchangeable with the primary outcome measure – overall survival – is becoming more and more relevant in oncology. The choice of criteria of efficacy should be made taking into account the specific features of a particular oncological disease, study population and duration of therapy. The authors of the study analysed Russian and foreign literary sources containing information on criteria of efficacy of anticancer medicines and highlighted the advantages and disadvantages of these criteria. The study showed that clinical endpoints should be clinically significant, sensitive to therapy, easy to measure and interpret. It was demonstrated that comprehensive evaluation of outcome measures makes it possible to adequately assess the risk-benefit ratio of anticancer medicines.
Physico-Chemical and Biological Properties of Biosimilar and Reference Tissue Plasminogen Activator Products
Authors: Gusarova V. D. , Pantyushenko M. S. , Simonov V. M. , Shukurov R. R. , Khamitov R. A. , Vishnevskiy A. Yu.
Published: March 2019

Recombinant tissue plasminogen activator (international nonproprietary name — alteplase) which was developed by «GENERIUM» (Russia) and received a marketing authorisation in Russia is completely analogous to Actilyse® which is used to treat medical conditions accompanied by thrombosis, such as acute myocardial infarction, pulmonary embolism, and ischemic stroke. The aim of the study was to carry out a comprehensive comparison of physico-chemical and biological properties of Revelyse® and the reference product Actilyse® in order to assess their biosimilarity. Materials and Methods: comparative peptide mapping and determination of comparability of chromatographic profiles of tryptic hydrolysates was performed using RP-HPLC and massspectrometry; the molecular weight distribution was determined by mass-spectrometry and polyacrylamide gel electrophoresis (Laemmli method). The purity and homogeneity of products as well as the content of related impurities (oligomers and fragments) were determined using gel filtration; N-glycosylation profile was analysed by hydrophilic HPLC, total sialic acid was quantified by the Svennerholm resorcinol method. Protein binding to fibrin and human fibrinogen was assessed by surface plasmon resonance, and the specific activity was compared by fibrin clot lysis. Results: the research demonstrated a complete overlap of the products’ peptide maps, which indicates the identity of аlteplase amino acid sequences in the two medicines being compared. The authors of the study also determined the molecular weight and the content of the intact single-stranded form of the protein, and quantified post-translational modifications, the content of sialic acids and neutral sugars. The analysis of the N-glycosylation profile revealed insignificant differences in the percentage of multiantenna complex glycans. The specificity of alteplase was evaluated by analysing the formation of protein complexes with natural alteplase ligands – fibrin and plasminogen activator inhibitor-1, but no significant differences were found. The comparison of specific activation of plasminogen fibrinolytic activity was performed based on the results of the assay analysing the fibrin clot lysis rate, and it demonstrated comparability of Revelyse® and Actilyse®. Conclusions: comparative experimental studies have shown no differences in the structure, charge distribution heterogeneity, impurities content, and specific activity of alteplase as a component of Revelyse® and the reference product Actilyse®, which leads to the conclusion that they are similar in terms of physicochemical and biological properties.
Ebelik Öğrencilerinin Gebelikte Şiddete Yönelik Mesleki Rollerine İlişkin Tutumları
Authors: Aydın Özkan Semiha , Karaca Türkan , Bilgiç Dilek
Published: March 2019

Amaç: Bu çalışma ebelik öğrencilerinin gebelikte şiddete
yönelik mesleki rollerine ilişkin tutumlarının belirlenmesi amacıyla
yapılmıştır.

Gereç ve Yöntem: Tanımlayıcı
tipte olan bu çalışma, 105 ebelik öğrencisi
ile yürütülmüştür. Verilerin toplanmasında “Kişisel Bilgi Formu” ve “Hemşirelerin
Şiddette Mesleki Rollerine İlişkin Tutumları Ölçeği” kullanılmıştır. Verilerin
analizinde non-parametrik testler kullanılmıştır. 

Bulgular: Ebelik öğrencilerinin yaş ortalaması 21.59
± 1.43 (min: 20 - maks: 23)’dür. Öğrencilerin gebelikte şiddete yönelik mesleki
rollerine ilişkin tutumlarının olumlu yönde olduğu ve mesleki rollerinde çağdaş yaklaşımları kullandıkları (29.27±7.36)
saptanmıştır. Öğrencilerin sınıfı, yaş grubu, yaşadığı bölge ve gebelikte
şiddete yönelik eğitim alma durumu ile şiddette mesleki rollerine ilişkin tutum
medyan puanları arasında anlamlı fark elde edilmiştir (p<0.05).

Sonuç: Ebelik
öğrencilerinin gebelikte uygulanan şiddete mesleki rollerine ilişkin
tutumlarının olumlu yönde, geleneksellikten uzak olduğu ve mesleki rollerinde çağdaş yaklaşımları kullandıkları
saptanmıştır. Ebelik öğrencilerinin şiddet gören gebeye yönelik destekleyici
tutum ve yaklaşım sergilediği saptanmıştır. Ebelik öğrencilerinin gebelikte
şiddet konusunda tutumlarının ortaya çıkarılması ile elde edilecek sonuçlar
doğrultusunda müfredat programında ayrı bir teorik ders olarak konuya yer
verilmesi önerilebilir.
Diz Osteoartritli Hastalarda Tamamlayıcı ve Alternatif Tedavi Kullanımı
Authors: Çalık Afra , Kapucu Sevgisun
Published: March 2019

Osteoartritli hastalar, genel olarak eklem ağrısı,
eklem hareket açıklığında kısıtlanma, kas güçsüzlüğü, eklem tutukluğu, eklem
şişliği ve fonksiyon kaybı gibi sorunlar yaşamaktadır. Bu nedenle hastaların
günlük yaşam aktiviteleri ciddi şekilde kısıtlanmakta ve yaşam kaliteleri
olumsuz etkilenmektedir. Osteoartrit hastalarının çoğunluğunda hastalığa bağlı
görülen semptomların etkin şekilde yönetilemediği bilinmektedir. Bu durum hem
hastaları hem de bakım verenleri semptomların yönetiminde farklı arayışlara
yönlendirmiş ve bu amaçla tamamlayıcı ve alternatif tıp uygulamaları
kullanılmaya başlanmıştır. Bu derlemenin amacı, diz osteoartritli hastalarda
tamamlayıcı ve alternatif tedavi kullanımı hakkında hemşireleri bilgilendirmek
ve bu alanda farkındalığı artırmaktır.Osteoartritli hastalar, genel olarak eklem ağrısı,
eklem hareket açıklığında kısıtlanma, kas güçsüzlüğü, eklem tutukluğu, eklem
şişliği ve fonksiyon kaybı gibi sorunlar yaşamaktadır. Bu nedenle hastaların
günlük yaşam aktiviteleri ciddi şekilde kısıtlanmakta ve yaşam kaliteleri
olumsuz etkilenmektedir. Osteoartrit hastalarının çoğunluğunda hastalığa bağlı
görülen semptomların etkin şekilde yönetilemediği bilinmektedir. Bu durum hem
hastaları hem de bakım verenleri semptomların yönetiminde farklı arayışlara
yönlendirmiş ve bu amaçla tamamlayıcı ve alternatif tıp uygulamaları
kullanılmaya başlanmıştır. Bu derlemenin amacı, diz osteoartritli hastalarda
tamamlayıcı ve alternatif tedavi kullanımı hakkında hemşireleri bilgilendirmek
ve bu alanda farkındalığı artırmaktır.
Trakeostomili Hastalarda Yaşam Kalitesi ve Hemşirelik Bakımı
Authors: Canbolat Seyman Çiğdem , Şenol Çelik Sevilay
Published: March 2019

Larenks
kanseri tüm malign tümörlerin %1-2’sini, baş-boyun bölgesi kanserlerinin
yaklaşık %40’ını oluşturmaktadır. İleri evre larenks kanserinin en etkili
tedavisi total larenjektomidir. Total larenjektomi ameliyatı sonrası trakeostomi
açılması ile hastaların yaşamları tümüyle değişmekte ve yaşam kaliteleri ömür
boyu baş etmek zorunda kaldıkları problemlerden dolayı olumsuz etkilenmektedir.
Bu nedenle trakeostomili hastalara bakım veren hemşirelerin, hastaların ve
ailelerinin bu sorunlarla baş etme becerisini artıracak şekilde bakım vermeleri
gerekmektedir. Bu makalede trakeostomisi olan bireyde yaşam kalitesini artırmada
hemşirelik bakımının önemi tartışılacaktır.
Total quality management implementation, and its barriers in Education system
Authors: Mehta Abhijit , Degi Faisal Rafik
Published: March 2019

The main purpose of this paper is to specify the thoughts of the modern era paradigm on Total quality management "TQM" and its application in the field of education. This research starts with the background theory/ literature review and then outline the result of the study, conducted by the students to obtain the different perspective on Total quality management in education. This sector needs improvement. It means that adoption of TQM in education gives you an excellent result in the overall system. As we can say that adoption of total quality management in education can ascertain more effective institutional change with success. As a result, this research proposed a theory which is obtained from TQM like institutional change environment, sustainable success, and innovation which express the relationship between the educational institutions and the role of total quality management.
Electrician’s Math and Basic Electrical Formulas Basic Electrical Formulas
Authors: Kim Seo H.
Published: March 2019

In order to construct a building that will last into the future, a strong foundation is a prerequisite. The foundation is a part of the building that isn’t visible in the finished structure, but is essential in erecting a building that will have the necessary strength to endure.The math and basic electrical concepts of this unit are very similar to the foundation of a building. The concepts in this unit are the essential basics that you must understand, because you’ll build upon them as you study electrical circuits and systems. As your studies continue, you’ll find that a good foundation in electrical theory and math will help you understand why the NEC contains certain provisions. This unit includes math and electrical fundamentals. You’ll be amazed at how often your electrical studies return to the basics of this unit. Ohm’s law and the electrical formulas related to it are the foundation of all electrical circuits. Every student begins at a different level of understanding, and you may find this unit an easy review, or you may find it requires a high level of concentration. In any case, be certain that you fully understand the concepts of this unit and are able to successfully complete the questions at the end of the unit before going on. A solid foundation will help in your successful study of the rest of this textbook.
Evaluating the Evidential Value of Empirically Supported Psychological Treatments (ESTs): A Meta-Scientific Review
Authors: Sakaluk John Kitchener , Williams Alexander , Kilshaw Robyn , Rhyner Kathleen T.
Published: March 2019

Empirically supported treatments (or therapies; ESTs) are the gold standard in therapeutic interventions for psychopathology. Based on a set of methodological and statistical criteria, the APA has assigned particular treatment-diagnosis combinations EST status and has further rated their empirical support as Strong, Modest, and/or Controversial. Emerging concerns about the replicability of research findings in clinical psychology highlight the need to critically examine the evidential value of EST research. We therefore conducted a meta-scientific review of the EST literature, using clinical trials reported in an existing online APA database of ESTs, and a set of novel evidential value metrics (i.e., rates of misreported statistics, statistical power, R-Index, and Bayes Factors). Our analyses indicated that power and replicability estimates were concerningly low across almost all ESTs, and individually, some ESTs scored poorly across multiple metrics, with Strong ESTs failing to continuously outperform their Modest counterparts. Lastly, we found evidence of improvements over time in statistical power within the EST literature, but not for the strength of evidence of EST efficacy. We describe the implications of our findings for practicing psychotherapists and offer recommendations for improving the evidential value of EST research moving forward.
Probability range and probability distortion in a gambling task
Authors: Xing Chenmu , Paul Joanna , Zax Alexandra , Cordes Sara , Barth Hilary , Patalano Andrea
Published: March 2019

In decision making under risk, adults tend to overestimate small and underestimate large probabilities (Tversky & Kahneman, 1992). This inverse S-shaped distortion pattern is similar to that observed in a wide variety of proportion judgment tasks (see Hollands & Dyre, 2000, for review). In proportion judgment tasks, distortion patterns tend not to be fixed but rather to depend on the reference points to which the targets are compared. Here, we tested the novel hypothesis that probability distortion in decision making under risk might also be influenced by reference points—in this case, references implied by the probability range. Adult participants were assigned to either a full-range (probabilities from 0-100%), upper-range (50-100%), or lower-range (0-50%) condition, where they indicated certainty equivalents for 176 hypothetical monetary gambles (e.g., “a 50% chance of $100, otherwise $0”). Using a modified cumulative prospect theory model, we found only minimal differences in probability distortion as a function of condition, suggesting no differences in use of reference points by condition, and broadly demonstrating the robustness of distortion pattern across contexts. However, we also observed deviations from the curve across all conditions that warrant further research.
Single dose versus multiple dose antibiotics in laparoscopic cholecystectomy: A prospective comparative single blind study
Authors: Koirala Ashok , Thakur Dipendra , Agrawal Sunit , Chaudhary Bhuwan Lal
Published: March 2019

Introduction: There is a controversy on single dose or multiple doses of prophylactic antibiotics for prevention of surgical site infection during laparoscopic cholecystectomy in a developing country setting. The objective of this study was to compare single versus multiple doses of prophylactic antibiotics in terms of surgical site infection in laparoscopic cholecystectomy patients.

Methods: This was a prospective, comparative, randomized study was conducted in a medical college hospital. Two hundred consecutive patients with symptomatic cholelithiasis planned for routine laparoscopic cholecystectomy were enrolled in the study. Patients were randomly divided in a Single dose (SD) group and multiple dose (MD) group. SD group were given injection ceftriaxone (1gm) before induction of anesthesia and MD group received ceftriaxone (1gm) before induction of anesthesia and continued a total of 3 doses postoperatively for next 24 hours.

Results: A total of 200 patients were studied, of which 100 were in single dose (SD group) and another 100 in multiple dose (MD group). The mean age of patients with symptomatic cholelithiasis was 41.76 ± 13.38 years with minimum of 16 years and maximum of 73 years. Of the total patients, 4 patients in single dose (SD) group and 3 patients in multiple dose (MD) group developed surgical site infection of various severity which was not statistically significant. (p=0.500).

Conclusion: There is no difference in terms of surgical site infection in patients taking either single or multiple doses of antibiotics in laparoscopic cholecystectomy in a medical college setting in Nepal.
Technical Notes and Result of Stereotactic Evacuation of Hematoma in Spontaneous Supratentorial Intracerebral Hematoma
Authors: Shrestha Resha , Shrestha Pranaya , Rajbhandari Pravesh , Acharya Samir , Dhakal Sudan , Limbu Chandra Prakash , Chandra Avinash , Pant Basant
Published: March 2019

Primary intracerebral hematoma constitutes about 10-15% of all strokes and is associated with high mortality and severe disability. Surgical treatment of intracerebral hemorrhage is quite controversial. It is believed that minimal invasive stereotactic surgery may reduce hematoma volume and decrease secondary neurotoxicity. The technical note of stereotactic surgery has been illustrated. A retrospective study from March 2016 to March 2018 has been conducted and all patients who underwent stereotactic evacuation of hematoma were included in this study. Baseline characteristics of patients and outcome in terms of Glasgow Coma Scale (GCS) and Modified Rankin Scale (mRS) have been shown. We have found significant improvement in GCS postoperatively, however mRS did not improve immediately but was significantly better in three months follow up period.
“Yet I’m Still a Man”: Disability and Masculinity in George R.R. Martin’sA Song of Ice and FireSeries
Authors: Tarnowski Amy
Published: March 2019

This article examines three fantasies concerning representations of disability and masculinity within George R.R. Martin’s A Song of Ice and Fire series. Specifically, I argue that within the fictional realm of Westeros, the treatment of Tyrion and Jaime Lannister reveals the cultural fantasies that influence how male characters with disabilities are defined, perceived, and treated by normate (non-disabled) characters. Tyrion and Jaime both subscribe to and challenge Westerosi fantasies that are projected onto individuals with disabilities—namely, the notion that individuals with disabilities are grotesque or monstrous, the belief that disability is a marker of immorality or divine punishment, and the stereotype that individuals who are disabled are emasculated or impotent. All of these cultural fantasies influence the marginalized status and positionality of characters like Tyrion and Jaime, and reveal normates’ anxieties concerning both bodily fragility and the maintenance of the hegemonic status of normate embodiment.
Effects of double-ageing on the mechanical properties and microstructural evolution in the 1460 alloy
Authors: Ma Juan , Yan Desheng , Rong Lijian , Li Yiyi
Published: March 2019

The effects of different double ageing processes on the mechanical properties and microstructural evolution in the 1460 alloy were investigated. The corresponding microstructure and mechanical properties of the heat-treated specimens were studied by means of transmission electron microscopy, differential scanning calorimetry, hardness testing and tensile testing. The results show that the elongation of two-step aged (130 °C/84 h + 160 °C/24 h) samples can be increased to 8 % with a minor decrease in tensile strength (450 MPa). Throughout the two-step ageing process, the precipitation behaviour of the alloy exhibited the following characteristics: the δ′ phase formed at lower temperature dissolved into the matrix instead of coarsening and becoming over-aged at the beginning of the second ageing step; finely distributed θ′(Al2Cu) and δ′(Al3Li) at a steady state were obtained, resulting in a significant improvement in tensile strength; and the peak ductility occurred with the precipitation of T1(Al2CuLi) and consumption of δ′(Al3Li), as small δ′ particles caused a co-planar slip, resulting in lower ductility.
Thermodynamic investigations in the Al–Fe system: Thermodynamic modeling using CALPHAD
Authors: Rank Maximilian , Franke Peter , Seifert Hans Jürgen
Published: March 2019

The Al–Fe system has been modeled and optimized with the CALPHAD approach. Heat capacity values from three intermetallic phases (stoichiometric compositions: Al2Fe, Al5Fe2 and Al13Fe4) were experimentally determined and implemented into the Gibbs energy descriptions, thus the estimated heat capacity from Neumann–Kopp is substituted. From these results together with new literature values, a revised dataset of the binary Al–Fe system is presented. Based on the Compound Energy Formalism, the homogeneity range of the Al2Fe and Al5Fe2 phase is represented using a two-sublattice model. In addition, the Al8Fe5 phase has been modeled with a four-sublattice model and the number of sublattices of the Al13Fe4 phase has been changed from a three-sublattice model to a two-sublattice model. The critically assessed parameters provide a consistent thermodynamic dataset and represent most of the relevant thermochemical data as well as phase diagram data within their experimental uncertainties.
Increasing cold workability of Ti-6Al-4V alloy via thermo-mechanical processing: simulation and experiment
Authors: Ahmadian Peyman , Morakabati Maryam , Abbasi Seyed Mehdi
Published: March 2019

Rolling temperature is thought to have a significant effect on the cold workability of Ti-6Al-4V alloy. To investigate the extent of this effect, four Ti-6Al-4V strips were hot rolled at different rolling temperatures in the range of 650–950 °C while other process parameters were invariant. The specimens revealed an increase in work hardening capacity with increase in rolling temperature, based on tensile and plane strain compression testing. After 10 % cold rolling, the same annealed samples exhibited propagation of edge cracks in specimens that had been hot rolled at 650, 750 and 850 °C while no cold rolling defect was found in the specimen hot rolled at 950 °C. The results of finite element method reveal that during cold rolling, the von Mises stress field is decreased as a result of increasing previous hot rolling temperature. In accordance with X-ray diffraction results, increasing previous hot rolling temperature is associated with lower lattice strain storage during subsequent cold rolling.
Artificial intelligence in the synthesis of creative solutions
Authors: Андрейчиков Александр , Andreychikov Aleksandr , Андрейчикова Ольга , Andreichicova Olga
Published: March 2019

Invention problem solving is connected to essential expenses of labour and time, which is spent on the procedures of search and ordering of necessary knowledge, on generation of probable vari-ants of projected systems, on the analysis of offered ideas and de-cisions and understanding perspectiveness of them. The present article outlines the results of the developments in the field of cre-ating computing technology of the synthesis of new engineering on the level of invention. The most attention is paid to problem of computer aided designing on initial stages, where synthesis of new on principal technical systems is carried out. Computer-aided con-struction of new technical system is based on using of data- and knowledge bases of physical effects and of technical decisions as well as different heuristic systematization procedures. The synthe-sis of principles of function of the technical new systems is carried out with using experts knowledge and requires the application of the artificial intelligence methods and the methods of the deci-sions making theory for invention's tasks. Considered approach has been used for synthesis of new technical systems of different functional purposes and had shown high efficiency in computer-aided construction.
The THE RELATIONSHIP BETWEEN ISLAMIC ATTRIBUTES DESTINATION AND SERVICE QUALITY ON DESTINATION LOYALTY WITH TOURIST SAISFACTION AS MEDIATING VARIABLE
Authors: Yuliviona Reni , Abdullah Mokhtar , Alias Zuraini , Sefnedi Sefnedi
Published: March 2019

This research study intends to investigate the tourist satisfaction as a mediating variable in the relationship between the Islamic attributes, service quality and destination loyalty among Malaysian Muslim tourists in the Padang city. A self survey was implemented as the means to attain the primary data among the 160 Malaysian Muslim tourists visiting the Padang city . The sample of 119 usable responses were collected from the 160. To analyze the model, Partial Least Squares structural equation modeling was utilized. The statistical outcomes established the positive and significant influence of the service quality, the Islamic attributes and the tourist satisfaction on destination loyalty. The results also established that tourist satisfaction were positively and significantly influenced by the service quality and the Islamic attributes. Along with it, tourist satisfaction mediated significantly in the relationship between the Islamic attribute, the service quality and the destination loyalty among the Malaysian Muslim tourists visiting in Padang city.
Modelling Afghanistanâ€™s Average Monthly Temperature from 1901 to 2015
Authors: Ismail Emal , Boudjella Aissa
Published: March 2019

The purpose of this investigation is to examine the variation of temperature in Afghanistan over the past 114 years. The historical dataset of the monthly average temperature from 1901 to 2015 were analyzed. The relationship between temperature and time during the four time intervals, i.e. (1901 -1930), (1931-1960), (1961-1990) and (1991-2015) is presented using a new analytical model based on the last â€“square method of estimation. We accurately fit a polynomial regression trend of degree 4 to the time series to describe the temperature variation. The results show the average difference of temperature between 2015 and 1901 increases about 1.03 Â°C. The average monthly difference between the maximum and minimum temperature was approximately 3.66 Â°C and the average monthly difference between the maximum and minimum temperature during these periods is approximately about 1.31 Â°C. This approach of modeling temperature using regression form significantly simplifies the data analysis. The information from data, namely the variation of the temperature, maybe be obtained from the extracted parameters such as slope, y-intercept, and the coefficients of polynomial function that are a function of time. More importantly, the parameters that describe the time variation temperature trends over 115 years obtained with a high R-squared do not vary significantly. This is in agreement with the Earthâ€™s average temperature that has climbed to more 1 Â°C  The evaluation of Afghanistanâ€™s past climate data can be extremely important for understanding how climate has varied along with their possible predictable outcomes that come with increasing drought risk due to gradual increase of temperature. These results may be useful for environmental policy makers in comprehension of climate change in Afghanistan. The results can help develop appropriate strategies for the environment, and regulate resource use or pollution reduction to promote human welfare and/or nature protection.
Influences of Alkaline and Salinity on Adsorption Capacity of Anionic Sodium Dodecyl Sulfate Surfactant
Authors: Tengku Mohd Tengku Amran , Jaafar Mohd Zaidi
Published: March 2019

Chemical losses in surfactant flooding could substantially degrade the efficiency of the process. This study aims to analyze the prospect of alkaline in minimizing surfactant adsorption. Static adsorption tests were conducted to investigate the adsorption of anionic sodium dodecyl sulfate (SDS) surfactant on local sand and kaolinite surfaces. Alkaline (sodium carbonate) ranging from 1wt% to 3wt% were added into the surfactant formulation with local sand or kaolinite at fixed volume to mass ratio of 5:1. Brine (sodium chloride) concentrations were varied from 1wt% to 3wt%. Equilibrium adsorption test was conducted by shaking the suspension for 24 hours, centrifuged and the supernatant sample was analyzed using UV-Vis spectrophotometer. The kinetics of surfactant adsorption was also analyzed by taking the suspension samples at every 30-60 minutes interval during the shaking process. Adsorption kinetics of SDS surfactant showed a nonlinear increase of the adsorption followed by a plateau. Adsorption on the kaolinite was found higher than the local sand. Increasing SDS concentration resulted in increase of adsorption on both local sand and kaolinite surfaces until reaching its micelle concentration. The increase in brine concentration also led to higher adsorption capacity, but alkaline addition has potentially reduced the adsorption due to higher repulsion force.
Dependence Modelling using GARCH, EGARCH, and Copula Models:
Authors: Aminuddin Jafry Nurul Hanis , Razak Ruzanna Ab , Ismail Noriszura
Published: March 2019

Copula become a popular tool to measure the dependency between financial data due to its ability to capture the non-normal distributions. Hence, this paper will inspect the impact of input models towards the parameter estimation of marginal and copula models for KLCI and FBMHS returns series by considering the ARMA-GARCH model and the ARMA-EGARCH model. This study also investigates the dependency of Islamic-conventional pair for Malaysia indices by using static copula and time-varying copula approach. The closing prices of Malaysia indices represented by KLCI (conventional) index and FBMHS (Islamic) index for the period of 21 May 2007 until 28 September 2018 are used as a sample data. The results show that KLCI-FBMHS pair is strongly correlated, different input models (ARMA-GARCH and ARMA-EGARCH) have identical dependence structure but slightly different value of parameter estimated, and the time-varying Gaussian copula is chosen as the best dependence model. Finding suggest that the diversification between Islamic-conventional pair is worthwhile during stable period.
Does the Diversity of Directors Moderates the Relationship between Prudently Governed Corporate Board and Decision to Pay the Dividend?
Authors: Mirza Nauman Iqbal , Malik Qaiser Ali
Published: March 2019

This study evaluates the moderating role of diversity in the board of directors on the relationship between Corporate Governance and dividend decisions of listed companies of Pakistan. This study further explores relationship between conventional accounting variables and dividend decisions. Multifaceted diversity of the board of directors encompassing age, experience and nationality is examined. Panel Data Analysis is used to measure the cause and effect relationship among the variables. General to specific modelling is used by including all the potential regressors. Results depict that Firm Size, Leverage and Experience Diversity of Board negatively effects the Dividend Decisions, while Earnings per Share, CEO Duality, Directors Nationality and Age effects positively. Furthermore Age and Nationality Diversity of directors significantly moderate the relationship between Corporate Governance and Dividend Decisions.
Consumersâ€™ Switching Preference from Conventional Food to Genetically Modified Food
Authors: Teng Phuah Kit , Heng Bernard Lim Jit , Abdullah Siti Intan Nurdiana Wong
Published: March 2019

Today, the demand for quality food is increasing and genetically modified food has become part of the Asian diet. Based on the potential of GM food products and Malaysiaâ€™s plan to expand its biotechnology industry, the market for GMO will surge if Malaysian consumers are well-informed on the advantages of GM food products. Therefore, this study proposed nine hypothesis to understand Malaysia consumersâ€™ preference for switch from conventional food to genetically modified food. The result indicates that utilitarian, aversive and informational reinforcement will increase consumersâ€™ preference towards genetic modified food if they are aware that genetically modified food brings more advantages than disadvantages to human being. In addition, result shows that consumer who switch will have higher intention to recommend GMO food to others and willing to pay more for GMO food.
Does strategic location strengthen the relationship between Service Quality, Customer Satisfaction And Customer Loyalty?
Authors: Agus Arawati binti
Published: March 2019

This study investigates the relationships between service quality determinants namely tangible, reliability, responsiveness, competency, courtesy and credibility, with customer satisfaction and loyalty in the context of Malaysian hypermarkets. The paper also investigates the mediating role of customer satisfaction and also determines whether location (from the strategic perspective) plays a significant moderating role in the customer satisfaction-customer loyalty linkage. The findings suggest that service quality has significant relationships with  customer satisfaction and customer loyalty measures. The result indicates that three service quality determinants specifically tangibles, courtesy and credibility demonstrate high associations with customer satisfaction and customer loyalty. The result suggests that customer satisfaction has significant mediating role in the relationship between service quality and customer loyalty. In addition, location moderates the linkage between customer satisfaction and customer loyalty in both directions. The findings suggest that a more strategic location of a hypermarket can strengthen the relationship between customer satisfaction and customer loyalty.