bluuebunny/crossref_metadata_2025 huggingface dataset:
Insights Into Challenges Faced by Interpreting Trainees and Their Error Patterns
Authors: AlDayel Reema S. , Alotaibi Hind M.
Published: March 2024

This study explored the challenges faced by trainees in Arabic and English interpreting by analyzing prevalent errors and investigating their underlying causes. A cohort of 31 female students underwent simultaneous interpretation tests in both languages. The data were used to identify challenges encountered during the interpretation process and analyze participants’ performance using Musa and Al-Maryani’s (2021) eclectic model. The study also examined the impact of L2 level on interpreting output. The findings show that omission is the most common error in interpreting both English and Arabic speech and is often employed as a coping technique for challenges such as speech speed, specialized terminology, structural differences, and numerical information. Hesitation was more pronounced when interpreting English into Arabic, indicating difficulties in directionality and language fluency. Regardless of language proficiency or level, all participants made similar errors when interpreting Arabic and English speech. These findings highlight the importance of developing comprehensive interpreter training that focuses not only on L2 proficiency, but also on strategies for managing the challenges encountered during interpretation, such as speech speed, specialized terminology, and directionality.
Language Maintenance: The Case of Modern Standard Arabic Among Bilinguals
Authors: Al-Khawaldeh Nisreen N. , Alomoush Omar I. , Khalaf Eman M. Al , Almahameed Yazan S. , Jaradat Abdullah A.
Published: March 2024

This study explores how Jordanians, especially bilinguals, can maintain the usage of Modern Standard Arabic (MSA). Despite the importance of this topic, it is a fairly unaddressed area of research in the Arabic context in general and Jordan in particular. The study contributes to knowledge by raising the awareness of Jordanians and authorities about the means necessary to maintain the usage of MSA among Jordanians. Data were collected via face-to-face semi-structured interviews with 50 Jordanian linguists and thematically analysed. The results revealed that many factors could contribute to the maintenance of MSA, including education systems, governmental policies, society, the media, and international relations. Specific actions to maintain MSA might include designing language policies in favour of MSA across different sectors; obtaining official recognition and social support; encouraging the dedication and motivation of educationalists, language specialists, and individuals; and raising awareness of the value of MSA. The study concludes with pedagogical implications and recommendations for further research.
Directive Speech Act Politeness in a Pediksaan Ritual: A Sociopragmatic Study
Authors: Rasna I Wayan , Suandi I Nengah , Putrayasa Ida Bagus , Paramarta Ketut
Published: March 2024

This study focused on the concern about the decrease in the use of language politeness among young people both in everyday communication and sacred Hindu rituals such as in a pediksaan ritual, in which not only the place is made sacred but also things related to the inauguration of a sulinggih (high priest) that is, performed in a Geria, home of a brahmana, who is still holding high the high cultural norms. This study analyzed the type of directive speech act politeness, the forms of language politeness, and the application of directive speech act politeness in the pediksaan ritual. The stages of a descriptive qualitative method were employed to achieve those objectives. The population of the study was the people involved in the activity of a pediksaan ritual. Since this event is rare, the population was directly used as the study's sample. The data were collected by observing the pediksaan ritual using a recording technique. The data collected were analyzed with a qualitative descriptive method. The study shows that the types of directive speech act politeness in this study are differentiated into linguistic politeness and pragmatic politeness; the forms of directive speech act politeness consist of (a) agreement maxim of suggesting; (b) sympathizing maxim of order and the politeness principles that consist of (a) the politeness principle that applies tact maxim; (b) the politeness principle that applies approbation maxim; and (c) the politeness maxim that applies sympathy maxim.
Techno-Economic Evaluation of Hyaluronic Acid Production Through Extraction Method using Yellowfin Tuna Eyeball
Authors: Elia Sheren Hana , Maharani Brigitta Stacia , Yustia Intan , Girsang Gabriela Chelvina Santiuly , Nandiyanto Asep Bayu Dani , Kurniawan Tedi
Published: March 2024

The purpose of this study is to determine the feasibility of a hyaluronic acid fabrication project by extraction and isolation of the fish eyeball, and we evaluated the results from an engineering and economic perspective. Engineering analysis was analyzed based on tools and raw materials that are available on e-commerce. The economic analysis was done using several economic parameters, such as gross profit margin, the length of time required for an investment to return the total initial expenditure, the condition of a production project in the form of a production function in years, project benefits, and so on. The production of Hyaluronic Acid nanoparticles has good prospects. Technical analysis of producing 50.4 g/L of Hyaluronic Acid nanoparticles per day shows the total cost of the equipment purchased to be 20,726 USD. The investment will be profitable after more than four years and compete with the capital market standard. To ensure the feasibility of a manufacturing project, the project is estimated from ideal conditions to the worst conditions in production activities, including raw materials, utilities, sales, labor, and external conditions. The project is prospective and profitable in the small-scale industry, confirmed by positive values in all economic parameters).
Evaluating the Performance of Supervised Machine Learning Algorithms in Breast Cancer Datasets
Authors: Obiwusi K. Y. , Olatunde Y. O. , Afolabi G. K. , Oke A. , Oyelakin A. M. , Salami A.
Published: March 2024

Breast cancer is the leading cause of mortality globally. Several attempts have been made to use data mining methodology together with machine learning techniques to develop systems that can detect or prevent breast cancer. In line with the reviewed paper; large datasets for illness analysis have been developed. In this study, the results of selected Machine Learning algorithms are compared: Decision Table, J48, SGD, bagging, and Naïve Bayes Updateable on Wisconsin Breast Cancer Original dataset was conducted using weka tools. Exploratory data analysis, pre-processed with supervised attribute selection and class order, was used to identify potential features to aid the performance of the chosen algorithms in classification. The empirical result showed that Decision Table explores greater likelihood (74% correctly classified instances, True Positive Rate of 0.752, False Positive Rate of 0.478, Precision of 0.77, receiver operating characteristic Area of 0.682) in terms of accuracy and efficiency compared with others. This study's comparison technique is thought to aid breast cancer detection.
Assessment of Air Quality Using the Plume Air Quality Index Indicator (PAQI): Reference to Five Towns in Nigeria
Authors: Abulude Francis Olawale , Acha Sunday , Adamu Ademola Samuel , Araifalo Kikelomo Mabinuola , Kenni Amoke Monisola , Bello Lateef Johnson , Gbotoso Arinola Oluwatoyin
Published: March 2024

Air quality is an important issue worldwide due to the health implications on man and livestock. For this reason, different countries constructed the air quality index (AQI) which depicts pollution levels and the impact on health. PAQI is an example of an air quality index built by Plume Labs, Paris, France. It has seven levels (Low, Moderate, High, Very High, Excessive, Extreme, and Airpocalypse) of pollution which are linked to the World Health Organization (WHO) limits. This study aimed to assess the AQI of five different towns in Nigeria using the satellite model data released by Plumes Labs. Daily data of the towns were recorded between 9 am and 7 pm for 60 days and statistically analyzed. The air quality index was determined by whatever pollutant was measuring the highest. It was observed that PM2.5 and 03 (30 and 40 respectively) had the highest concentration levels most times. The results were compared with the PAQI indicator. The air quality of the towns has reached high levels of pollution above the maximum limit for 24 hours established by WHO.
The Development of Intelligent Tutoring System in The Military Schools
Authors: Kurniawan Bobi , Meyliana M. , Warnars Harco Leslie Hendric Spits , Suharjo Bambang
Published: March 2024

The rapid and fast development of technology affects many aspects of life, especially in the field of education. The application of technology in education is needed to support a more effective and efficient learning process without any space and time constraints. An example is the implementation of the Intelligent Tutoring System (ITS) which is often known as an intelligent learning system. An ITS in the field of military education is needed to produce professional military graduates/HR. Therefore, researchers will examine trends in research development and updates on ITS technology in the military field. Efforts to achieve research objectives are carried out using the Systematic Literature Review method with bibliometric analysis or VOSviewer. The purpose of this study is to become a reference for determining research topics on ITS in the field of education, especially the military.
Neurotechnology Applied to Medicine. Analysis of Patients Undergoing Neuro Endoscopy in Triventricular Obstructive Hydrocephalus
Authors: Gonzalez-Argote Javier
Published: March 2024

Hydrocephalus is the condition that has benefited the most from neuroendoscopy and is largely responsible for its emergence. The purpose of this study was to evaluate the application of endoscopic third ventriculostomy to treat obstructive triventricular hydrocephalus in the Neurosurgery Department. A descriptive study was conducted in a hospital in the Buenos Aires suburbs involving patients admitted to the neurosurgery department diagnosed with obstructive triventricular hydrocephalus. We reviewed 37 male patients (75.5 %) and 12 female patients (24.5 %). Hydrocephalus grade II was observed in 87.7%, and only 16.3% were associated with transependymal flow and hydrocephalus grade III. These imaging signs allowed us to diagnose the type of obstructive triventricular hydrocephalus, as well as to have an initial reference for postoperative evaluation and follow-up of diagnosed patients, relying on the dimensions of the third ventricle, Evans index, and Morlan scale for hydrocephalus grade, enabling quantification of these signs during their progression.
Use of Blockchain technology for the exchange and secure transmission of medical images in the cloud: Systematic Review with Bibliometric Analysis
Authors: Lizama Maria Guzman , Huesa Jair , Claudio Brian Meneses
Published: March 2024

The research questions focused on emerging challenges, solutions, approaches, encryption methods, architectures, and opportunities related to blockchain technology in medical image sharing, and a total of 17 relevant articles were selected from the Scopus database for analysis. The increasing adoption of cloud computing environments in the medical field has raised concerns about security and privacy risks. Within these concerns, problems were identified regarding secure data storage, since centralized storage systems in the cloud mostly lack security effectiveness. Blockchain technology offers a decentralized and secure infrastructure to address these problems. However, a systematic review is needed to identify the strengths and limitations of this technology in this context, therefore the objective of this review is to provide a critical and updated view of the security aspects of the use of blockchain technology in the exchange of medical images in the cloud. The proposed solutions included practical byzantine fault tolerance algorithms, homomorphic encryption, and the integration of smart contracts, among others. In conclusion, this review provides insight into the application of blockchain technology for the secure sharing of medical images in the cloud and identifies key technologies, challenges, solutions, and opportunities in the field.
Chatbot Artificial Intelligence as Educational Tools in Science and Engineering Education: A Literature Review and Bibliometric Mapping Analysis with Its Advantages and Disadvantages
Authors: Al Husaeni Dwi Fitria , Haristiani Nuria , Wahyudin W. , Rasim R.
Published: March 2024

This research was conducted to analyze the application, utilization or use of AI chatbots in the education sector based on several previous studies. Bibliometric analysis is used to identify the current status of research and critical points in bibliometric data mapping can help predict future research trends. Data searches were carried out on the Scopus database with the keywords "Chatbot" AND "education" with a research year range of 2007-2024. There were 376 articles found. The research results show that research on chatbots, especially in the education sector, is increasingly in demand. In 2023 there will be a drastic increase in the number of studies regarding chatbots in the education sector compared to previous years. This is because chatbots are considered to be an interesting tool to use in education because they enable a more innovative teaching process in terms of improving learning processes and outcomes. There are 25 countries that have contributed to related research, with the United States, Australia, United Kingdom, China and Taiwan in the top five. This research also shows that there are 26 subject areas that have used chatbots in the education sector. The use of chatbots in the education sector has advantages and disadvantages. With the completion of this research, it is hoped that it can become material for consideration for related research.
A Conceptual Curriculum Design Approach for Educating Engineers of and for the Future
Authors: Namasivayam Satesh , Al-Obaidi Abdulkareem Sh. Mahdi , Fouladi Mohammad Hosseini
Published: March 2024

The 4th Industrial Revolution (I4) highlights the demand for engineers equipped with technical expertise, emotional intelligence, communication, leadership, and critical thinking skills to navigate the complexities of modern engineering. This conceptual paper presents a future-oriented approach to engineering curriculum development, emphasizing the adoption of Outcome-Based Education (OBE) and project-based learning. The integration of key frameworks, such as the Conceive Design Implement Operate (CDIO) model and blended learning techniques, enhance the learning experience. The curriculum aims to align with global goals, including the UN Sustainable Development Goals and the 14 Grand Challenges for Engineering. An innovative curriculum is designed to inspire students' passion for engineering and engage them with emerging technologies, such as additive manufacturing and artificial intelligence. By equipping graduates with the necessary skills and knowledge, this curriculum strives to make a significant impact on society, fostering sustainability and addressing complex engineering challenges. This paper contributes to the field of engineering education by providing a comprehensive and forward-thinking approach to curriculum development.
Assessment of Iron Contamination in Groundwater of Catchment Area Water
Authors: Boutebib Aichetou Brahim , N’diaye Abdoulaye Demba , Elhoumed Sid’Ahmed Baba , M’Baye Bocar Kalidou , El Hadj Ali Youssef Aoulad , Hammouti Belkheir , Semega Bakari Mohamed
Published: March 2024

This study investigates the occurrence of iron (Fe) in the catchment area water in Derwiche from Hodh El Chargui in Mauritania. The study area was monitored during January and August. The occurrence of Fe in the groundwater showed significant spatial and temporal fluctuations. The relationship between Fe and some physicochemical parameters was also analyzed statistically using Pearson’s correlation matrix. Firstly, the results suggested that the concentration of Fe was influenced by the dissolution of iron minerals. Secondly, the results show that the pH value was an important factor that influenced the Fe concentrations in the groundwater. The Water Quality Index (WQI) method was used to evaluate the suitability for human consumption. The results show that WQI is strongly influenced by Fe indicating that Fe removal would contribute to excellent well water. The Treatability Index (TI) is used to assess water quality. TI confirms the results obtained by the WQI. However, TI also shows that the pH is a parameter to be optimized for possible potabilization. These results show that there would be a close relationship between the recorded Fe levels and the pH. TI confirms the results obtained by Pearson’s correlation matrix. Therefore, the presence of high Fe concentrations in groundwater in the study area could have a natural origin. The results recommended that different treatment techniques should be employed to purify groundwater before consumption. The primary focus should be cascaded toward Fe contamination.
How to Make and Characterize Hydroxyapatite from Eggshell Using the Hydrothermal Method: Potential Insights for Drug Delivery System
Authors: Irwansyah Ferli Septi , Amal Alfi Ikhlasul , Hadisantoso Eko Prabowo , Noviyanti Atiek Rostika , Eddy Diana Rakhmawaty , Risdiana Risdiana , Suryana Suryana , Zain Shariffuddin Bin Md
Published: March 2024

Hydroxyapatite (HA) has garnered significant attention as a versatile biomaterial with promising applications in drug delivery systems. This study aimed to synthesize and characterize HA derived from eggshells using the hydrothermal method and explore its potential insights for drug delivery systems. We delivered a step-by-step process to produce HA using a hydrothermal method, supported by several analyses, X-Ray Diffraction (XRD) to analyze the crystallinity structure, Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Particle Size Analyzer (PSA), and Brunauer-Emmett-Teller (BET). The stage is continued with a study on the potential of HA as a drug delivery system with UV-Visible spectrophotometer instrumentation. The results suggest that the characterized HA suits drug delivery systems due to its favorable properties. This study contributes to the understanding of utilizing hydroxyapatite from eggshells as a viable material for drug delivery systems, opening avenues for further research and development in this field.
Characteristics of Tamarind Seed Biochar at Different Pyrolysis Temperatures as Waste Management Strategy: Experiments and Bibliometric Analysis
Authors: Rahmat Ali , Sutiharni Sutiharni , Elfina Yetti , Yusnaini Yusnaini , Latuponu Hadidjah , Minah Faidliyah Nilna , Sulistyowati Yeny , Mutolib Abdul
Published: March 2024

Household activities and beverage industries that use tamarind often generate waste in the form of tamarind seeds. Tamarind seeds account for approximately 40% of the total weight of the fruit. If these tamarind seeds are not properly managed, they end up as waste with no economic or other benefits. One effective waste management strategy is to convert tamarind seeds into biochar. This research aims to examine the characteristics of biochar produced from tamarind seeds at different pyrolysis temperatures. The results indicate that as the pyrolysis temperature increases, the fixed carbon content also increases. Pores begin to form on the surface of the biochar at a temperature of 400°C. We have identified functional groups such as C-H, O-H, C≡N, C≡C, C=C, C=O, CH3, C-O, and C-C in the biochar. The dominant elements in tamarind seed biochar are K2O, CaO, P2O5, SO3, and MgO, which are part of macronutrients and alkaline elements with the potential to improve soil quality as soil amendments.
Augmented Reality for Cultivating Computational Thinking Skills in Mathematics Completed with Literature Review, Bibliometrics, and Experiments for Students
Authors: Angraini Lilis Marina , Susilawati Aay , Noto Muchamad Subali , Wahyuni Reni , Andrian Dedek
Published: March 2024

The research problem centered around the need to enhance students' computational thinking (CT) ability, which is crucial for their success in the present and future. This study aims to examine the efficacy of Augmented Reality (AR) in improving the CT abilities of seventh-grade junior high school students. The study utilized a quasi-experimental design with a control group and an experimental group to meet the research aims. The control group was provided with conventional mathematical instruction through established teaching methods, while the experimental group was exposed to mathematics learning enhanced by AR media. The study involved 160 students from four junior high schools located in one of the cities in Indonesia. A five-question CT ability test was employed as the research instrument.  The mean difference test was used to analyze the data and compare the performance of the control and experimental groups. The research findings indicated that the effective application of AR media significantly enhanced the CT skills of seventh-grade adolescents in middle school.  The results aid in creating new teaching approaches and emphasize the possibilities of AR technology in math education.
Image Detalization as an Indicator of Figurative and Plastic Creativity of Preschoolers
Authors: Gorshkova E.V.
Published: March 2024

Based on a brief description of creativity and imagination, their indicators and age characteristics, the insufficiency of research on the creativity of preschoolers is shown. A diagnostic study (1993–2000) is described, aimed at identifying the age characteristics of children 3–7 years old in detailing the motor-plastic image. 192 children participated in the diagnosis according to the author's method "Hare and Wolf"; they were asked to embody the plot of the "fairy tale" by means of the movement language. It was revealed: in the younger group, schematic movements predominate, signifying the image; in the middle group, the proportion of "complex" figurative movements is growing; in the senior and preparatory groups, "complexes" (partial and integral) prevail and the number of sequences of figurative movements that convey the phases of the character's actions is growing. Statistical analysis (according to the criteria H Kruskal-Wallis and U Mann-Whitney) revealed significant differences in image detail between different age samples and the absence of such differences between boys and girls (in different years).
Aspectos clínicos e histopatológicos em câncer de pulmão
Authors: N. B. R. Alves Fernanda , S. Pedro Wilson José , R. Afonso João Pedro , A. Souza Shayra Kellen , O. Moura Barbara , P. M. Neto Joaquim , S. I. Tabata Keyci , R. Alves Larissa , V. Braga Lenita , André Ribeiro Marcos , V. Barbosa Júnior Flávio , Hanna Helias , A. de Oliveira Danúbio , A. Galdeano Patrícia Regina , A. A. Galdeano Pedro , B. S. Ribeiro Júnior Jairo , F. de Oliveira Rodrigo , R. Freitas Júnior Wilson , F. de Oliveira Luís Vicente
Published: March 2024

Aspectos clínicos e histopatológicos em câncer de pulmão
Breast cancer development coordinated by changes in microenvironment setting
Authors: Jurić Bernardica , Ulamec Monika , Krušlin Božo , Balja Melita
Published: March 2024

Breast cancer is the most common malignancy in women worldwide, and one of the leading causes of cancer death. This disease shows a significant heterogeneity due to its genomic and histological diversity. Breast cancer is classified by pathologic features (i.e. histological subtype, tumor grade) and gene expression profiles (i.e. molecular subtypes). There are complex mechanisms implicated in its progression and the development of chemotherapy resistance. In recent times, tumor stroma is increasingly being recognized as an important factor which influences tumor pathogenesis and progression. Tumor-stromal cells interactions are involved in many phases of tumor growth, by modulating different cellular processes. Tumor-infiltrating lymphocytes are proven to be clinically significant as they correlate with good prognosis, especially in triple-negative and HER2-positive breast cancer patients. However, tumor-infiltrating lymphocytes are just one of the many components of the tumor microenvironment, which includes fibroblasts, macrophages, adipocytes, vascular cells etc., but also non-cellular components. One of the main cellular components of the tumor microenvironment are the fibroblasts which are activated and differentiated into breast cancer associated fibroblasts. They secrete many growth factors, cytokines, and chemokines which influence tumor growth and dissemination. Tumor microenvironment could be a source of new biomarkers with a potential predictive and prognostic significance. This review highlights the tumor microenvironment as an important contributor to the process of cancer development with an overview of the main components and the potential impact on the prognosis of breast cancer. It’s important to expand our understanding and knowledge of tumor-stromal signalling processes which may lead to the development of more successful and individualized therapeutic strategies.
Neuropsychological Changes Across Life Stages and Their Impact on Spirituality
Authors: Sacco Robert
Published: March 2024

This study examines neuropsychological changes across life stages and their impact on spirituality. Focusing on infancy to old age, it explores how the brain’s evolution influences spiritual perception and experiences. Key findings include the foundational role of early brain development in shaping basic spiritual awareness and the significant transformation during adolescence and early adulthood, marked by deep questioning and exploration of spiritual identity. The research highlights that peak spiritual experiences and brain complexity may coincide around age 18, suggesting a crucial period for spiritual exploration. In contrast, older adulthood, despite potential cognitive decline, often leads to a deepening of spiritual life, characterized by reflection and wisdom. The study underscores the interconnectedness of neuropsychological development and spirituality, emphasizing the importance of considering spiritual well-being alongside physical and mental health. It concludes that spirituality is a vital, evolving aspect of the human experience, closely linked to neuropsychological changes throughout life.
Robotic-Assisted and Computer-Assisted Navigation Surgery in the Cervical Spine: Current Experiences, Techniques, and Accuracy
Authors: Avrumova Fedan , Altorfer Franziska , Lebl Darren
Published: March 2024

Background: In recent years, the role of robotic-assisted and computer-assisted navigation (RA-CAN) systems has significantly expanded in spine surgery, particularly those performed in the thoracic, lumbar and sacral spine showing higher accuracy in pedicle screw placement and improved surgical efficiency. However, there are few reports on these techniques in the cervical spine. The anatomy of the cervical spine possesses additional challenges such as the close proximity to critical neurovascular structures. Purpose: In this article, we present the existing clinical experience of RA-CAN in the cervical spine and evaluate technical considerations. Cervical spine screw fixation and decompression using RA-CAN are reviewed. Results: This analysis covers various aspects such as techniques, accuracy, and the types of procedures reported in the literature. Recent reports include surgical procedures such as anterior cervical diskectomy and fusion’s, odontoid fracture fixation, C1 lateral mass, C2 pedicle, translaminar, subaxial spine lateral mass, and mid-cervical spine pedicle screw fixation. There is potential for enormous clinical benefit to navigated decompression in cervical CAN procedures also. Future opportunities include further improvements in imaging co-localization, pre-surgical planning software, and mechanization of surgical procedures for instrumentation and decompression. Conclusion: The growth of RA-CAN in spinal surgery has shown significant potential in its application in the cervical spine for fusion procedures as well as decompression. By understanding the potential limitations and techniques reported from early experiences, previous techniques can be improved and provide further benefits for accuracy and less invasive surgery.
Aetiological Diagnosis of children with False Diagnosis of Arthrogryposis Multiplex Congenita
Authors: Kaissi Ali , Ryabykh Sergey , Kaissi Hamza , Dougales Vasileios , Kenis Vladimir , Kircher Susanne , Grill Franz
Published: March 2024

Background: Arthrogryposis multiplex congenita is the usual misdiagnosis given for children born with multiple joint dislocation syndromes. The purpose of the study was to refute the term arthrogryposis multiplex congenita as well as contractures and replace them with a precise diagnostic entity. Methods: Eight unrelated children referred to our orthopaedic departments with the presumptive misdiagnosis of arthrogryposis multiplex because of multiple joint contractures. Five boys and three girls (aged 1 month-5 year) and one adult-15-year-old-boy have been included. We performed extensive clinical and radiographic phenotypic characterization of every single patient associated with confirmatory genotype. Results: We accomplished the diagnoses in all these children. Three diagnostic entities emerged. Larsen syndrome, diastrophic dysplasia and Escobar syndrome. The genotype has been performed accordingly. Conclusion: The reason for presenting this study is threefold; Firstly, to illustrate the necessity of the etiological diagnosis in children with the misdiagnosis of arthrogryposis multiplex congenita in connection with the presumptive misdiagnosis of fetal akinesia, Pena-Shokeir syndrome or congenital myopathy. Secondly, full consideration of the phenotypic characterization and the additional pathological features allowed us to achieve proper management. Thirdly, is to clarify that excessive vigorous attempts to correct the dislocations in children with skeletal dysplasia were felt to not be recommended because of the risk of damaging the dysplastic epiphyses.
TUBERCULOSIS IS A LOOMING NEXT PANDEMY
Authors: Maes Roland
Published: March 2024

Tuberculosis kills today one person in 14 seconds in India and one in 12 seconds worldwide, i.e. about 4000 people every day, worldwide. The victims are largely invisible because they are confined in sanatoria and do not encumber regular hospitals, as did the coronavirus pandemy of 2020. The coronavirus pandemy has put in glaring light the fragility of the elder, the minorities and the health agents exposed, as does TB. It also generated heathed discussions about drugs, vaccines, pathology, diagnosis and prognosis. The virus also causes significant immunological changes in the infected. It is a catastrophe but also the end-result of a predicted and foreseen tragedy: the destruction of our health systems and the deval- uation of the idea of Public Health. The mayhem of coronavirus may repeat itself with the foreseen rise of tuberculosis, whose characteristics resemble much those of the coronavirus. This bacterium is currently neglected but may, precisely because of this corona pandemy, expand again.
Effects of High-Dose Selenium on Mortality of Sepsis and Septic Shock Patients with Severe Selenium Deficiency in Taiwan
Authors: Chen Chun-Man , Chen Yen-Ling , Lin Shu-Min , Wu Huang-Pin , Lin Jiun-Nong , Lin Kai-Huang , Chen Chin-Ming , Yang Kuang-Yao , Ku Shih-Chi , Chung Fu-Tsai , Kuo Chih-His , Chiu Chien , Hsu Chi-Kuei , Hsu Hsin-Hui , Chu Chien-Ming , Hu Han-Chung , Lee Chung-Shu , Wu Shin-Hwar , Mao I-Chieh , Chao Ting-Yu , Chu Yi-Wen , Chien Du-Shieng
Published: March 2024

The relationship between serum selenium levels and mortality was investigated in septic patients with severe selenium deficiency (baseline selenium ≤ 80 ng/mL). Eligible patients of sepsis or septic shock were randomized to receive Placebo or High-Dose Selenium (1,000 μg/day) via intravenous injection. Safety, serum selenium, mortality, SOFA, and Glasgow Coma Scale (GCS) scores were monitored. Among all 330 subjects, 27.9% subjects (n=92) had severe selenium deficiency (mean serum selenium = 66.5 ng/mL). Mortality of severe selenium deficiency patients was 27.2%, significantly higher than 17.9% of all subjects. In severe selenium deficiency Placebo group (n=45), 62% subjects showed gradual increase of selenium levels to ~110 ng/mL (mortality ~21.4%), while 38% subjects remained at low selenium ≤ 110 ng/mL throughout study (mortality ~41.2%). Mortality for Placebo subjects with normal baseline selenium ≥ 110 ng/mL was 13.6%. With High-Dose Selenium treatment, 91% of severe selenium deficiency subjects showed quick selenium increase to ~110 ng/mL (mortality 25.5%). Mortality was reduced to 8.6% for High-Dose Selenium subjects with baseline selenium ≥ 110 ng/mL. The odds ratio showed significantly greater survival of High-Dose Selenium subjects with baseline selenium ≥ 110 ng/mL (91.4%) than severe selenium deficiency Placebo subjects (74.1%). Mean baseline SOFA scores for severe selenium deficiency patients were 9.1–9.4, decrease of SOFA scores in High-Dose Selenium subjects was significantly greater than Placebo subjects, along with significant improvement of GCS scores. Repeated infusion of High-Dose Selenium in severe selenium deficiency patients for 14 days was safe and well-tolerated. Mortality for patients with sepsis was clearly affected by serum selenium concentrations. High mortality (41–50%) was observed in the sepsis patients constantly with low selenium £ 80 ng/mL; mortality was reduced to 21–23% if their serum selenium could be increased to ≥ 110 ng/mL. High-Dose Selenium resulted in rapid restoration of serum selenium and improved the survival of severe selenium deficiency septic patients. Low mortality (9–14%) was observed in the sepsis patients starting with baseline selenium ≥ 110 ng/mL. Overall this study demonstrates the significant impact of insufficient selenium levels on the mortality of septic patients. Treatment with high-dose selenium reduced the mortality of severe selenium deficiency septic subjects.
Anti-Inflammatory Effect of Extracts of Inonotus obliquus and Microalgae
Authors: Wagle Sajeev , Thilakarathna Wasitha , Lee Julie , Rupasinghe H.P.
Published: March 2024

Chaga mushroom (Inonotus obliquus) and marine microalgae are two emerging natural products with many potential physiological health benefits. The aim of this study was to investigate the anti-inflammatory effects of two extracts prepared from Chaga mushroom and microalgae using lipopolysaccharide-stimulated RAW 264.7 murine macrophage cell model. The Chaga mushroom extract dose-dependently reduced the production of proinflammatory biomarkers of interleukin (IL)-6 and tumor necrosis factor-alpha (TNF-α). At a high concentration of 500 µg/L, Chaga mushroom extract significantly suppressed cyclooxygenase-2 levels. Similarly, the extract of microalgae suppressed the secretion of IL-6 and TNF-α by lipopolysaccharide-induced macrophages. Both extracts had no significant impact on the secretion of anti-inflammatory IL-4 production. These results suggest that extracts of Chaga mushroom and microalgae can be used in developing anti-inflammatory natural health products.
Vaccine-induced T-helper-1 and endocrine therapy in an estrogen receptor alpha low breast cancer model
Authors: Cecil Denise , Gad Ekram , Corulli Lauren , Potts Kevin , Disis Mary
Published: March 2024

The standard of care options for patients with triple negative breast cancer is limited to primarily surgery and chemotherapy. Recent evidence has demonstrated that combining immune therapeutic strategies with standard therapies increased efficacy in clinical trials and mouse models of breast cancer. Endocrine therapy, such as tamoxifen, has traditionally only been used to treat estrogen receptor positive breast cancer, but results of early tamoxifen clinical trials have revealed increased clinical activity in estrogen receptor-negative/low tumors. The goal of this study was to determine if combination immune therapy and endocrine therapy could inhibit tumor growth in an estrogen receptor-low mouse model. We observed that immunization targeting the tumor antigen insulin-like growth factor receptor-1 inhibited tumor growth dependent on interferon-gamma-secreting CD4+ T-cells. Interferon-gamma upregulated expression of the tumor suppressor phosphatase and tensin homolog in vitro. Vaccination induced sensitivity to treatment with either tamoxifen or anastrozole and the combination therapy was more effective than any single agent alone. Our study suggests that strategies incorporating antigen-specific type I T cells in conjunction with non-standard endocrine therapy regimens can improve outcomes in patients with triple negative breast cancer.
Особенности учета себестоимости объектов в строительстве
Authors: Григорьева Д.Р. , Ахтямзянов Р.И.
Published: March 2024

Рассмотрена классификация методов учета себестоимости строительных объектов. Проанализированы существующие варианты учета затрат. Для строительной отрасли предложено использовать позаказный метод.
Подходы к развитию ценностного компонента функциональной грамотности на уроках английского языка
Authors: Антонова А.А.
Published: March 2024

Данная статья посвящена проблеме развития ценностного компонента функциональной грамотности учащихся средней общеобразовательной школы на уроках английского языка. Автор описывает практический опыт и результаты применения некоторых подходов.
Воспитание любви к русскому языку у младших школьников при организации проекта «Познай родной язык!» во внеурочной деятельности
Authors: Антохина В.А. , Макарова Е.Д. , Титова В.И.
Published: March 2024

В статье рассматривается актуальная проблема воспитания любви к родному языку у младших школьников при организации внеурочной деятельности. Обосновывается эффективность реализации проектов в решении задачи воспитания у младших школьников любви к родному языку как основе патриотизма. Для обсуждения представлен проект «Познай родной язык!», апробированный в реальной школьной практике.
Изучение культуры родного края в образовательных организациях Белгородской области
Authors: Баджурак О.А. , Грушина М.В. , Косова М.А.
Published: March 2024

В статье рассматривается проблема изучения истории родного края в современных образовательных реалиях. Современное поколение утрачивает связь времен. В статье описывается опыт изучения культуры родного края в урочной и внеурочной деятельности педагога профессиональной образовательной организации.
Влияние прослушивания музыкального творчества Инстасамки на самооценку студентов-психологов
Authors: Семенихина В.А. , Дворцова Е.В.
Published: March 2024

В данной статье рассмотрены основные понятия самооценки. Представлены результаты математико-статистического анализа влияния музыкального творчества Инстасамки на самооценку студентов-психологов, на основании эмпирических данных, полученных в процессе проведения собственного диагностического исследования.
Влияние просмотра фильма «Движение вверх» на мотивацию студентов-психологов
Authors: Сергеев В.Д. , Дворцова Е.В.
Published: March 2024

Обучение в ВУЗе – это тяжѐлый труд, и зачастую, студентам не хватает мотивации во время учѐбной деятельности, что может негативно сказываться на их успеваемости. Мотивация у студентов во время учебной деятельности во многом зависит как от удовлетворѐнности выбранной ими профессии, личностных особенностей студентов, так и от их результатов, а также от самого процесса обучения. Если студент замотивирован, у него формируются личностные качества, которые помогают ему в достижении поставленных целей, например, самостоятельность, терпеливость, сила воли, и многие другие. Мотивация играет свою роль не только в учебной сфере, но и многих других сферах жизнидеятельности. Именно мотивация является движущим фактором человека, помогающим ему в личностном развитии, обучении, в преодолении жизненных трудностей, в поиске путей нахождения решения проблем, а также, в удовлетворении себя и своих потребностей.
Влияние стиля семейного воспитания на личностную тревожность подростков
Authors: Хомякова М.М.
Published: March 2024

Семья оказывает огромное влияние на развитие личности ребенка, в ней закладываются основы понимания ребенком мира, формируются взгляды и отношение к окружающим. Семья является главным институтом воспитания, дает определенные образцы поведения, которым подражают дети. Характер эмоционального отношения к ребенку не всегда оказывает положительное влияние на формирующуюся личность, что может приводить к тревожности детей на постоянной основе. В данной статье рассмотрено влияние стиля семейного воспитания на личностную тревожность подростка.
Сущностные аспекты архетипа «самость»: в контексте формирования основ психологии деятельности руководителя служебного коллектива системы ОВД России
Authors: Чимаров С.Ю.
Published: March 2024

В статье представлен анализ общей характеристики архетипа «самость», представленной швейцарским психологом К.Г. Юнгом и имеющей важное значение для оценки личностных качеств человека и многих аспектов его поведения. По мнению автора, постижение руководителем служебного коллектива феномена самости позволит отмеченному должностному лицу: во-первых, повысить уровень своей общей эрудиции и обеспечить понимание им глубинных причин ряда шаблонов служебной деятельности подчиненного личного состава; во-вторых, предопределит более предметное определение некоторых направлений его работы, с учетом осознания им психологии личности.
Влияние типа памяти на учебную успеваемость младших школьников
Authors: Юсифова С.А.
Published: March 2024

В статье рассматривается сравнение типов памяти у младших школьников, также каким образом типы памяти могут влиять на учебную успеваемость младших школьников в теоретическом плане.
Акцентированное кино как феномен мультикультурализма
Authors: Барышникова В.В.
Published: March 2024

Вторая половина ХХ века отмечена перемещением по миру огромного количества мигрантов. Это привело к появлению мультикультурных государств, в которых признается равенство всех существующих на их территории культур. Перед мигрантами, оказавшимися в новой культурной среде, встает вопрос о собственной идентичности. Именно в это время создаются фильмы, снятые авторами, находящимися в изгнании, представителями диаспор, выходцами из бывших колоний. Иранский исследователь диаспор, переселенцев, постколониальных СМИ и кинематографа Хамид Нафиси выделил кинопроизведения мигрантов в отдельную категорию – акцентированное кино. В отличие от доминантного голливудского кинематографа, отличающегося развлекательностью и отсутствием идеологии, акцентированные фильмы обладают акцентом не только в лингвистическом отношении, но и личностным переживанием авторов опыта миграции.
Наставничество как образовательный тренд современности
Authors: Валеева К.Д. , Занкина Е.В.
Published: March 2024

Данная статья исследует роль наставничества в современной образовательной практике и его статус как актуального образовательного тренда. В статье рассматривается концепция наставничества, его ценность в контексте развития учащихся и студентов, а также влияние наставничества на формирование ключевых компетенций и личностного роста обучающихся. Анализируются вызовы и перспективы внедрения наставничества в учебные процессы и подчеркивается его роль в формировании качественных образовательных практик в современном мире.
«Мастерские СНО» как площадка для развития научных исследований и привлечения студентов к научной деятельности
Authors: Княжева Е.А. , Княжева С.А. , Шак М.П. , Шаповал В.А.
Published: March 2024

Изданием Указа Президента РФ «Об объявлении в Российской Федерации Десятилетия науки и технологий» (2022-2031 гг.) способствует проведению мероприятий, направленных на развитие научной среды. Данная статья посвящена анализу и обобщению опыта реализации научного мероприятия «Мастерские СНО» . Проведена оценка мнений о серии «Мастерских», а также предложены меры совершенствования по реализации мероприятия.
Материнский капитал: проблемы и перспективы развития в России
Authors: Колесников А.Е. , Нестерова Н.В.
Published: March 2024

Данная научная статья посвящена вопросу материнского капитала, основных проблемах его использования, а также различные перспективы развития данного института в России. Автором исследования затрагиваются вопросы, касающиеся повышения эффективности и улучшение качества материнского капитала.
Социальная структура французского общества
Authors: Нуруллина Э.Р. , Мильчик А.А.
Published: March 2024

Проведенное исследование направлено на изучение особенностей социальной структуры общества Франции. Социальная структура общества любого государства дает возможность оценить состояние и степень зрелости общественных отношений. Она является итогом экономического, политического и духовного формирования общества и, одновременно, сама активно воздействует на это развитие.
Тысяцкий – роль данной должности в истории великого княжества московского
Authors: Дворянкин О.А.
Published: March 2024

В статье исследуются положения связанные с историческим происхождением должности «Тысяцкий» в истории Великого княжества Московского. Изучается роль тысяцкого в иерархической структуре княжества, ее функции, характеристики, особенности, статусность и влияние, как на руководителей города, так и на его жителей.
Образование в Вологодской губернии в начале ХХ века
Authors: Кашу К.А.
Published: March 2024

В статье анализируется исторический опыт подготовки профессиональных кадров в Вологодской губернии в конце XIX – начале XX в. Дана характеристика различных типов учебных заведений: ремесленных школ, отделений при городских и уездных училищах, краткосрочных курсов, Вологодского молочно-хозяйственного института, проанализированы требования к поступающим в данные учебные заведения и требования к преподавательскому составу, содержание, цели и задачи профессионального обучения в исследуемый период.
Синхронный перевод: особенности, преимущества и сложности
Authors: Селезнева О.Н.
Published: March 2024

Синхронный перевод является востребованным и актуальным средством международной коммуникации. Исторически синхронному переводу предшествовал последовательный перевод; оба вида перевода сосуществуют в настоящее время, при этом важнейшим преимуществом синхронного перевода является существенная экономия времени говорящего и реципиента. В статье рассматриваются технические требования и психолингвистические характеристики, необходимые для успешного осуществления синхронного перевода, а также его преимущества и сложности.
Об концепте «friend» и «дўст» в английском и таджикском языках
Authors: Хайдарова П.И. , Бобоева З.Х.
Published: March 2024

В статье рассматривается вопрос понятия «друг» и «пыл» в английском и таджикском языках. Отмечается, что исследуемая тема играет ключевую роль в изучении сравнительного языкознания.
Активные операции коммерческого банка (на примере ПАО «Банк Уралсиб»)
Authors: Вдовкина М.А. , Бичева Е.Е.
Published: March 2024

В статье рассмотрены виды активных операций коммерческого банка, исследована динамика активов банковской системы РФ за последние 5 лет, проведен анализ состава и структуры активов ПАО "Банк Уралсиб".
Рабочие листы как средство формирования познавательного интереса на уроках окружающего мира
Authors: Ворсобина Н.В. , Иванюшкина А.И. , Тюленева В.В.
Published: March 2024

В статье рассматривается проблема формирования познавательного интереса на уроках окружающего мира в начальной школах, и важность еѐ решения для качества образования и мотивации учеников. Авторы подчеркивают недостатки традиционной лекционной формы обучения и называют рабочие листы одним из наиболее эффективных средств активизации учебного процесса и развития когнитивных способностей детей. Рабочие листы помогают учащимся активизировать мыслительную деятельность на уроке, обнаруживать новые факты и закономерности, анализировать и систематизировать полученные знания, развивать навыки самостоятельной работы.