bluuebunny/crossref_metadata_2025 huggingface dataset:
Fig S6 from Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations
Authors: Flanagan Dustin J. , Barker Nick , Costanzo Natasha S. Di , Mason Elizabeth A. , Gurney Austin , Meniel Valerie S. , Koushyar Sarah , Austin Chloe R. , Ernst Matthias , Pearson Helen B. , Boussioutas Alex , Clevers Hans , Phesse Toby J. , Vincan Elizabeth
Published: April 2023

Figure S6. IHC for b-catenin, Myc, gastrin and Muc5a in Apc.Fzd7.TffCre adenoma tissue.
Fig S3 from Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations
Authors: Flanagan Dustin J. , Barker Nick , Costanzo Natasha S. Di , Mason Elizabeth A. , Gurney Austin , Meniel Valerie S. , Koushyar Sarah , Austin Chloe R. , Ernst Matthias , Pearson Helen B. , Boussioutas Alex , Clevers Hans , Phesse Toby J. , Vincan Elizabeth
Published: April 2023

Figure S3 depicts experimental design, body weight and tissue histology of gp130F/F animals following treatment with vehicle or OMP-18R5.
Figure S7-8 from Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer
Authors: Tacconi Carlotta , Ungaro Federica , Correale Carmen , Arena Vincenzo , Massimino Luca , Detmar Michael , Spinelli Antonino , Carvello Michele , Mazzone Massimiliano , Oliveira Ana I. , Rubbino Federica , Garlatti Valentina , Spanò Salvatore , Lugli Enrico , Colombo Federico S. , Malesci Alberto , Peyrin-Biroulet Laurent , Vetrano Stefania , Danese Silvio , D’Alessio Silvia
Published: April 2023

S7 LEC immunosuppressive function. Related to Figure 5. S8Macrophage depletion strategy. Related to Figure 6
Fig S1 from Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations
Authors: Flanagan Dustin J. , Barker Nick , Costanzo Natasha S. Di , Mason Elizabeth A. , Gurney Austin , Meniel Valerie S. , Koushyar Sarah , Austin Chloe R. , Ernst Matthias , Pearson Helen B. , Boussioutas Alex , Clevers Hans , Phesse Toby J. , Vincan Elizabeth
Published: April 2023

Figure S1 shows the relative expression of Fzd receptors in gastric cancer cells.
Figure S4 from Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer
Authors: Tacconi Carlotta , Ungaro Federica , Correale Carmen , Arena Vincenzo , Massimino Luca , Detmar Michael , Spinelli Antonino , Carvello Michele , Mazzone Massimiliano , Oliveira Ana I. , Rubbino Federica , Garlatti Valentina , Spanò Salvatore , Lugli Enrico , Colombo Federico S. , Malesci Alberto , Peyrin-Biroulet Laurent , Vetrano Stefania , Danese Silvio , D’Alessio Silvia
Published: April 2023

Ovalbumin immunization is enhanced by VEGFR3 blockage. Related to Figure 3
Figure S3 from Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer
Authors: Tacconi Carlotta , Ungaro Federica , Correale Carmen , Arena Vincenzo , Massimino Luca , Detmar Michael , Spinelli Antonino , Carvello Michele , Mazzone Massimiliano , Oliveira Ana I. , Rubbino Federica , Garlatti Valentina , Spanò Salvatore , Lugli Enrico , Colombo Federico S. , Malesci Alberto , Peyrin-Biroulet Laurent , Vetrano Stefania , Danese Silvio , D’Alessio Silvia
Published: April 2023

Systemic delivery of VEGFC induces lymphangiogenesis and TAM recruitment. Related to Figure 2
Figure S7: Supplementary Figure 7: PMTRIP FISH-PLA can quantify PolyA-HuR interactions in frozen colon tissue. from Quantification and Localization of Protein–RNA Interactions in Patient-Derived Archival Tumor Tissue
Authors: Blanchard Emmeline L. , Argyropoulou Danae , Zurla Chiara , Bhosle Sushma M. , Vanover Daryll , Santangelo Philip J.
Published: April 2023

Supplementary Figure 7: PMTRIP FISH-PLA can quantify PolyA-HuR interactions in frozen colon tissue. A) 5 nM of V5 tagged PMTRIPs targeting polyadenylated mRNA were delivered as FISH probes to tissue samples. PLA (green) was performed between the V5 tag and HuR. Extended focus images are shown, with a 1 mm scale bar. B) Extended focus cropped images of full tissues in (A) are indicated by white boxes. Extended focus images of tissue FISH-PLA at 63x are also shown. Scale bars are 100 μm for 20x and 10 μm for 63x images. C) Quantification of PLA signal in (A) is shown. Standard deviations are shown in red.
Figure S5: PMTRIP FISH-PLA can quantify PolyA-TIAR interactions in lung tissue. from Quantification and Localization of Protein–RNA Interactions in Patient-Derived Archival Tumor Tissue
Authors: Blanchard Emmeline L. , Argyropoulou Danae , Zurla Chiara , Bhosle Sushma M. , Vanover Daryll , Santangelo Philip J.
Published: April 2023

Supplementary Figure 5: PMTRIP FISH-PLA can quantify PolyA-TIAR interactions in lung tissue. A) 5 nM of V5 tagged PMTRIPs targeting polyadenylated mRNA were delivered as FISH probes to colon cancer samples. PLA (green) was performed between the V5 tag and TIAR. Extended focus images are shown, with a 1 mm scale bar for full tissue. B) Extended focus images of FISH-PLA (green) controls are shown. Scale bar is 1 mm. C) Extended focus cropped image of full tissues in (A) are indicated by white boxes. Scale bars are 100 μm. D) Extended focus image of tissue FISH-PLA at 63x is shown. Scale bar is 10 μm. E) Extended focus cropped images of full tissues in (B) are indicated by white boxes. Extended focus images of tissue FISH-PLA at 63x are also shown. Scale bars are 100 μm for 20x images and are 10 μm for 63x images. F) Quantification of PLA signal in (A, B). Statistics were performed with a one-way ANOVA with a Tukey's multiple comparisons test, where n=3 and ** p < 0.0087. Standard deviations are shown in red.
Supplementary Materials and Methods from miR-192-5p Silencing by Genetic Aberrations Is a Key Event in Hepatocellular Carcinomas with Cancer Stem Cell Features
Authors: Gu Yuanzhuo , Wei Xiyang , Sun Yulin , Gao Hongjun , Zheng Xin , Wong Linda L. , Jin Ling , Liu Niya , Hernandez Brenda , Peplowska Karolina , Zhao Xiaohang , Zhan Qi-Min , Feng Xin-Hua , Tang Zhao-You , Ji Junfang
Published: April 2023

It includes additional materials and methods, i.e., Plasmids, siRNAs, and LY294002 treatment; assays to examine cell malignancy features; qPCR and Western blot.
Figure S4: PMTRIP FISH-PLA can quantify COX-2-TIAR interactions in colon tissue. from Quantification and Localization of Protein–RNA Interactions in Patient-Derived Archival Tumor Tissue
Authors: Blanchard Emmeline L. , Argyropoulou Danae , Zurla Chiara , Bhosle Sushma M. , Vanover Daryll , Santangelo Philip J.
Published: April 2023

Supplementary Figure 4: PMTRIP FISH-PLA can quantify COX-2-TIAR interactions in colon tissue. A) 20 nM of V5 tagged PMTRIPs targeting COX-2 mRNA were delivered as FISH probes to colon cancer samples. PLA (green) was performed between the V5 tag and TIAR. Extended focus images are shown, with a 1 mm scale bar. B) Extended focus images of FISH-PLA (green) controls are shown. Scale bar is 1 mm. C) 20x cropped image for (A) are shown, as indicated by the white boxes. Extended focus images are shown, with a 100 μm scale bar. D) Extended focus image of tissue FISH-PLA at 63x is shown, with a 10 μm scale bar. COX-2 FISH shown in red. E) Extended focus cropped images of full tissues in (B) are indicated by white boxes. Extended focus images of tissue FISH-PLA at 63x are also shown. COX-2 FISH shown in red. Scale bars are 100 μm for 20x and 10 μm for 63x images. F) Quantification of PLA signal in (a-b). Statistics were performed with a one-way ANOVA with a Tukey's multiple comparisons test, where n=3 and * p < 0.046. Standard deviations are shown in red. G) Immuohistochemistry for TIAR was performed on colon cancer and healthy colon tissue. Single plane representative images are shown. Scale bars are 50 μm. Quantification of the area of HuR expression normalized by the area of nuceli is shown. Statistics were a Mann-Whitney t-test, where n= 5 and * p < 0.032.
Figure S3: PMTRIP FISH-PLA can quantify PolyA-TIAR interactions in colon tissue. from Quantification and Localization of Protein–RNA Interactions in Patient-Derived Archival Tumor Tissue
Authors: Blanchard Emmeline L. , Argyropoulou Danae , Zurla Chiara , Bhosle Sushma M. , Vanover Daryll , Santangelo Philip J.
Published: April 2023

Supplementary Figure 3: PMTRIP FISH-PLA can quantify PolyA-TIAR interactions in colon tissue. A-C) Cells were treated with 5 μ g/ml of ActD 1 h prior to fixation. 5 nM of V5 tagged PMTRIPs targeting polyadenylated mRNA were delivered as FISH probes. PLA was performed between the V5 tag and HuR. PLA signal is quantified by A) the number of PLA puncta, B) volume of PLA signal, or C) the sum of intensities of PLA signal per cell. Statistics were performed with a one-way ANOVA with a Dunn's multiple comparisons test, where n=30, ** p < 0.002, and **** p < 0.0001. 95% confidence intervals are shown in red. D) 5 nM of V5 tagged PMTRIPs targeting polyadenylated mRNA were delivered as FISH probes to colon cancer samples. PLA (green) was performed between the V5 tag and TIAR. Extended focus images are shown, with a 1 mm scale bar for full tissue. E) Extended focus images of FISH-PLA (green) controls are shown. Scale bar is 1 mm. F) Extended focus cropped images of full tissues in (D) are indicated by white boxes. Scale bars are 100 μm. G) Extended focus image of cancer tissue FISH-PLA at 63x is shown. Scale bar is 10 μm. h) Extended focus cropped images of full tissues in (E) are indicated by white boxes. Extended focus images of control tissue FISH-PLA at 63x are also shown. Scale bars are 100 μm for 20x and 10 μm for 63x images. I) Quantification of PLA signal in (D-E). Statistics were performed with a one-way ANOVA with a Tukey's multiple comparisons test, where n=3 and ** p < 0.0075. Standard deviations are shown in red.
Fig S1. from miR-192-5p Silencing by Genetic Aberrations Is a Key Event in Hepatocellular Carcinomas with Cancer Stem Cell Features
Authors: Gu Yuanzhuo , Wei Xiyang , Sun Yulin , Gao Hongjun , Zheng Xin , Wong Linda L. , Jin Ling , Liu Niya , Hernandez Brenda , Peplowska Karolina , Zhao Xiaohang , Zhan Qi-Min , Feng Xin-Hua , Tang Zhao-You , Ji Junfang
Published: April 2023

The distribution of CSC hepatic markers and the expression of CSC-miRNAs in HCC cohorts.
Supplementary File 7 from Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids
Authors: Laddha Saurabh V. , da Silva Edaise M. , Robzyk Kenneth , Untch Brian R. , Ke Hua , Rekhtman Natasha , Poirier John T. , Travis William D. , Tang Laura H. , Chan Chang S.
Published: April 2023

Differentially expressed genes between AC and TC of LC1
Supplementary File 6 from Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids
Authors: Laddha Saurabh V. , da Silva Edaise M. , Robzyk Kenneth , Untch Brian R. , Ke Hua , Rekhtman Natasha , Poirier John T. , Travis William D. , Tang Laura H. , Chan Chang S.
Published: April 2023

TMA data for ASCL1 and S100 of 173 LCs
Supplementary Table S6 from EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis
Authors: Peluffo Guillermo , Subedee Ashim , Harper Nicholas W. , Kingston Natalie , Jovanović Bojana , Flores Felipe , Stevens Laura E. , Beca Francisco , Trinh Anne , Chilamakuri Chandra Sekhar Reddy , Papachristou Evangelia K. , Murphy Katherine , Su Ying , Marusyk Andriy , D'Santos Clive S. , Rueda Oscar M. , Beck Andrew H. , Caldas Carlos , Carroll Jason S. , Polyak Kornelia
Published: April 2023

List of genes differentially expressed in SUM159 cells expressing shNLGN4X.
Supplementary File 5 from Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids
Authors: Laddha Saurabh V. , da Silva Edaise M. , Robzyk Kenneth , Untch Brian R. , Ke Hua , Rekhtman Natasha , Poirier John T. , Travis William D. , Tang Laura H. , Chan Chang S.
Published: April 2023

LC gene signature classifier and gene list
Supplementary File 3 from Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids
Authors: Laddha Saurabh V. , da Silva Edaise M. , Robzyk Kenneth , Untch Brian R. , Ke Hua , Rekhtman Natasha , Poirier John T. , Travis William D. , Tang Laura H. , Chan Chang S.
Published: April 2023

Differentially expressed genes between three LC subtypes and pathway analysis
Supplementary Table S4 from EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis
Authors: Peluffo Guillermo , Subedee Ashim , Harper Nicholas W. , Kingston Natalie , Jovanović Bojana , Flores Felipe , Stevens Laura E. , Beca Francisco , Trinh Anne , Chilamakuri Chandra Sekhar Reddy , Papachristou Evangelia K. , Murphy Katherine , Su Ying , Marusyk Andriy , D'Santos Clive S. , Rueda Oscar M. , Beck Andrew H. , Caldas Carlos , Carroll Jason S. , Polyak Kornelia
Published: April 2023

FOXA1 peaks in MCF7 cells expressing lacZ or EN1-V5.
Supplementary File 1 from Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids
Authors: Laddha Saurabh V. , da Silva Edaise M. , Robzyk Kenneth , Untch Brian R. , Ke Hua , Rekhtman Natasha , Poirier John T. , Travis William D. , Tang Laura H. , Chan Chang S.
Published: April 2023

Clinical characterization and tumor purity
Supplementary Data from Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids
Authors: Laddha Saurabh V. , da Silva Edaise M. , Robzyk Kenneth , Untch Brian R. , Ke Hua , Rekhtman Natasha , Poirier John T. , Travis William D. , Tang Laura H. , Chan Chang S.
Published: April 2023

Supplementary Figure 1: Subtype LC2 specific MEN1 loss of heterozygosity. Supplementary Figure 2: PCA on gene expression for top variable number of genes. Supplementary Figure 3: Pearson correlation on top 3000 variable genes. Supplementary Figure 4: Heatmap of top 100 variable genes. Supplementary Figure 5: PCA of top variable number of CpG sites. Supplementary Figure 6: Boxplot of gene expression of HNF1A, FOXA3 and HNF4A across three LC subtypes. Supplementary Figure 7: Low expression of HOX family members in LC2 subtype. Supplementary Figure 8: Heatmap of LCs classifier from 30 LC dataset on independent lung carcinoids cohort from Fernandez-Cuesta et al. Supplementary Figure 9: Heatmap of HNF1A, FOX3 and FEV on Fernandez-Cuesta et al gene expression dataset. Supplementary Figure 10: Key targets of ASCL1 transcription factor. Supplementary Figure 11: Clinical features of three LC subtypes for median age of diagnosis. Supplementary Table1: Tumor purity scores for 30 LC samples using gene expression profile. Supplementary Table2: Significant Pathways/Gene Ontologies for top 100 variable genes. Supplementary Table3: Global methylation CpG count under hypo (beta <0.3) and hyper (beta >=0.7) methylated probes for 18 LC samples. Supplementary Table4: IHC staining results for ASCL1 and S100 biomarker in 20 LC dataset
Supplementary Methods and Figure Legends from IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis
Authors: Bishnupuri Kumar S. , Alvarado David M. , Khouri Alexander N. , Shabsovich Mark , Chen Baosheng , Dieckgraefe Brian K. , Ciorba Matthew A.
Published: April 2023

Supplementary Methods and Figure Legends
Supplementary Figure Legends from Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas
Authors: Ohka Fumiharu , Shinjo Keiko , Deguchi Shoichi , Matsui Yusuke , Okuno Yusuke , Katsushima Keisuke , Suzuki Miho , Kato Akira , Ogiso Noboru , Yamamichi Akane , Aoki Kosuke , Suzuki Hiromichi , Sato Shinya , Arul Rayan Nirmala , Prabhakar Shyam , Göke Jonathan , Shimamura Teppei , Maruyama Reo , Takahashi Satoru , Suzumura Akio , Kimura Hiroshi , Wakabayashi Toshihiko , Zong Hui , Natsume Atsushi , Kondo Yutaka
Published: April 2023

This file is the legends of Supplementary FigureS1-S7
Supplementary Figures S1-S6 from IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis
Authors: Bishnupuri Kumar S. , Alvarado David M. , Khouri Alexander N. , Shabsovich Mark , Chen Baosheng , Dieckgraefe Brian K. , Ciorba Matthew A.
Published: April 2023

Additional data on (1) Ido-iKO mouse model; (2) Westerns for mTor; (3) Full KP metabolites effects on HT29 and DLD1 cells; (4) Ky effect on wound closure; (5) Apoptosis by staurosporine; (6) Westerns for Cox2 and Src.
Supplementary Figures and Tables from Early Loss of Histone H2B Monoubiquitylation Alters Chromatin Accessibility and Activates Key Immune Pathways That Facilitate Progression of Ovarian Cancer
Authors: Hooda Jagmohan , Novak Marián , Salomon Matthew P. , Matsuba Chikako , Ramos Romela I. , MacDuffie Emily , Song Melissa , Hirsch Michelle S. , Lester Jenny , Parkash Vinita , Karlan Beth Y. , Oren Moshe , Hoon Dave S. , Drapkin Ronny
Published: April 2023

Supplementary Figures and Tables - Figure S1. RNF40 somatic copy number alterations in a cohort of 579 HGSOC cases from The Cancer Genome Atlas (TCGA). Heterozygous loss of RNF40 is present in 36% of HGSOCs. Figure S2A. H2Bub1 stain intensity dot plot. Figure S2B. Distribution of H2Bub1 immunoreactivity (% positive cells). Figure S2C. Immunohistochemical analysis of Total H2B and H2Bub1 levels in invasive high-grade serious ovarian cancer. Figure S3. Stable RNF20 and H2Bub1 depletion escalates oncogenic behavior in FTSEC cell lines. Figure S4. Transient RNF20 and H2Bub1 depletion escalates oncogenic behavior in FTSECs. Figure S5. RNF20-depletion changes chromatin accessibility and redistributes open chromatin. Figure S6. RNF20-depletion changes chromatin accessibility and alters gene expression of immune signaling pathways in FTSEC cells. Figure S7. RNF20 and H2Bub1 deficiency alters the levels of cytokines. Figure S8. Representative images for RNA in situ hybridization of IL6 expression in FFPE tumor and normal tissue sections. Supplementary Table 1. Antibody information and staining conditions for immunohistochemistry (IHC).
Supplementary Data from DNA–SWCNT Biosensors Allow Real-Time Monitoring of Therapeutic Responses in Pancreatic Ductal Adenocarcinoma
Authors: Bhattacharya Santanu , Gong Xun , Wang Enfeng , Dutta Shamit K. , Caplette Joseph R. , Son Manki , Nguyen Freddy T. , Strano Michael S. , Mukhopadhyay Debabrata
Published: April 2023

Supporting data file contains absorption spectra, PL spectra, Raman spectra, size distribution of (GT)15-SWCNT. Also spatial distribution of (GT)15-SWCNT in vitro and in vivo presented more elaborately.
All Supplementary Tables, Figures and Methods from Bicyclic Peptides as a New Modality for Imaging and Targeting of Proteins Overexpressed by Tumors
Authors: Eder Matthias , Pavan Silvia , Bauder-Wüst Ulrike , van Rietschoten Katerine , Baranski Ann-Christin , Harrison Helen , Campbell Spencer , Stace Catherine L. , Walker Edward H. , Chen Liuhong , Bennett Gavin , Mudd Gemma , Schierbaum Ursula , Leotta Karin , Haberkorn Uwe , Kopka Klaus , Teufel Daniel P.
Published: April 2023

The file contains supplemental details related to sequence information of the bicyclic peptides referred to in the text, binding data, organ distribution data, PK parameters, mouse and human plasma stability, in vivo metabolism of BCY-B2 in mice, cell binding and internalization data, additional PET imaging data. It also contains detailed methods related to protein expression, phage selection, peptide synthesis, affinity determination by fluorescence polarization and SPR, radiolabeling, internalization, confocal microscopy, plasma protein binding, plasma stability of radiolabeled compounds, ÂµPET imaging, autoradiography, immunohistochemistry, and 6 references related to these methods. Â€¢ Supplementary Tables S1 - S14: o Table S1: Affinities and plasma stabilities of BCY-B and stabilized BCY-C. o Table S2: Sequence information and binding data of bicyclic peptides referred to in text. o Table S3: Surface plasmon resonance (SPR) data. o Table S4-6: Organ distribution data, BCY-B3/B4 o Table S7: PK parameters. o Table S8: Selectivity data of BCY-C towards other metalloproteinases. o Table S9-11: Organ distribution data- BCYC2/C4 o Table S12-14: Organ distribution data- BCYD1/D2 o Table S15: Organ distribution data- MAb Â€¢ Supplementary Figures S1-S6: o Figure S1: Comparative HT1080 cell binding and internalization of non-stabilized BCY-B3 and stabilized BCY-C2 o Figure S2: Organ distribution time course studies with active BCY-B3, and inactive BCY-B4 in HT1080 xenograft mice. o Figure S3: Mouse and human plasma stability of BCY-B5, BCY-C3, BCY-D1; o Figure S4: Pharmacokinetic profile of BCY-B2 in mouse; o Figure S5: In vivo metabolism of BCY-B2 in mice; o Figure S6: Confocal microscopy on HT1080 cells and BCY-C2 o Figure S7: PET imaging. Time-resolved whole-body maximum intensity projections of 68Ga-BCY-C2 in HT1080 xenograft mouse. Â€¢ Supplementary Methods: o Protein expression, o Phage selection, o Peptide synthesis, o Affinity determination by fluorescence polarization and SPR, o Radiolabeling, o Internalization, o Confocal microscopy, o Plasma protein binding, o Plasma stability of radiolabeled compounds, o ÂµPET imaging, o Autoradiography, o Immunohistochemistry, o 6 references related to these methods.
Table S2 from miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells
Authors: Mukohyama Junko , Isobe Taichi , Hu Qingjiang , Hayashi Takanori , Watanabe Takashi , Maeda Masao , Yanagi Hisano , Qian Xin , Yamashita Kimihiro , Minami Hironobu , Mimori Koshi , Sahoo Debashis , Kakeji Yoshihiro , Suzuki Akira , Dalerba Piero , Shimono Yohei
Published: April 2023

Detailed description of gene mutations of the two PDX lines.
Figure S5 from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance
Authors: Dalin Simona , Sullivan Mark R. , Lau Allison N. , Grauman-Boss Beatrice , Mueller Helen S. , Kreidl Emanuel , Fenoglio Silvia , Luengo Alba , Lees Jacqueline A. , Vander Heiden Matthew G. , Lauffenburger Douglas A. , Hemann Michael T.
Published: April 2023

Fig. S5. PSC lines exhibit heterogeneity in expression of fibroblast activation markers (A) Staining of the indicated PSCs lines with DAPI and aSMA and PDGFRb antibodies. Scale bars are indicated in the bottom right corner of each image. (B-C) Histogram of pixel intensity in the images in part A. (D) Staining of the indicated PSCs lines with DAPI and a fibronectin antibody. Scale bars are indicated in the bottom right corner of each image. (E) Histogram of pixel intensity in the images in part D. (F) Quantification of pixel intensity in aSMA and PDGFRb channels over a horizontal slice of each image in part A.
Figure S6 from miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells
Authors: Mukohyama Junko , Isobe Taichi , Hu Qingjiang , Hayashi Takanori , Watanabe Takashi , Maeda Masao , Yanagi Hisano , Qian Xin , Yamashita Kimihiro , Minami Hironobu , Mimori Koshi , Sahoo Debashis , Kakeji Yoshihiro , Suzuki Akira , Dalerba Piero , Shimono Yohei
Published: April 2023

Suppression of the organoid-forming capacities of HCT116 cells by QKI-5.
Figure S5 from miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells
Authors: Mukohyama Junko , Isobe Taichi , Hu Qingjiang , Hayashi Takanori , Watanabe Takashi , Maeda Masao , Yanagi Hisano , Qian Xin , Yamashita Kimihiro , Minami Hironobu , Mimori Koshi , Sahoo Debashis , Kakeji Yoshihiro , Suzuki Akira , Dalerba Piero , Shimono Yohei
Published: April 2023

A. Representative images of organoids. B. Effect of miR-221 knockdown on the expression levels of stem cell-related genes.
Supplementary Table 1 from Novel Third-Generation EGFR Tyrosine Kinase Inhibitors and Strategies to Overcome Therapeutic Resistance in Lung Cancer
Authors: Murtuza Ayesha , Bulbul Ajaz , Shen John Paul , Keshavarzian Parissa , Woodward Brian D. , Lopez-Diaz Fernando J. , Lippman Scott M. , Husain Hatim
Published: April 2023

Clinical Outcomes with Various Third Generation EGFR Inhibitors
Supplementary Figure 2 from Novel Third-Generation EGFR Tyrosine Kinase Inhibitors and Strategies to Overcome Therapeutic Resistance in Lung Cancer
Authors: Murtuza Ayesha , Bulbul Ajaz , Shen John Paul , Keshavarzian Parissa , Woodward Brian D. , Lopez-Diaz Fernando J. , Lippman Scott M. , Husain Hatim
Published: April 2023

Chemical Structures of Third Generation Anti-EGFR Compounds
Figures S1-S5, Table S1 from Melanoma Extracellular Vesicles Generate Immunosuppressive Myeloid Cells by Upregulating PD-L1 via TLR4 Signaling
Authors: Fleming Viktor , Hu Xiaoying , Weller Céline , Weber Rebekka , Groth Christopher , Riester Zeno , Hüser Laura , Sun Qian , Nagibin Vasyl , Kirschning Carsten , Bronte Vincenzo , Utikal Jochen , Altevogt Peter , Umansky Viktor
Published: April 2023

Figure S1 shows PD-L1 upregulation induced by EV that is mediated by NF-kB activation; Figure S2 shows an induction of PD-L1 and immunosuppressive capacity of myeloid cells through TLR signaling; Figure S3 presents characterization of EV derived from human melanoma cells; Figure S4 shows induction of PD-L1 expression on normal monocytes by melanoma EV; Figure S5 shows HSP86 expression in HT-144 human melanoma cells and HT-144-EV; Table S1 presents the sequences of primers for the quantitative real-time PCR
Supplementary Table 1 from MEK Inhibition Modulates Cytokine Response to Mediate Therapeutic Efficacy in Lung Cancer
Authors: Xie Mengyu , Zheng Hong , Madan-Lala Ranjna , Dai Wenjie , Gimbrone Nicholas T. , Chen Zhihua , Kinose Fumi , Blackstone Sarah A. , Smalley Keiran S.M. , Cress W. Douglas , Haura Eric B. , Rix Uwe , Beg Amer A.
Published: April 2023

Microarray data expression values shown in Figure 1E
Table S5J-part3 from Integrated Pan-Cancer Map of EBV-Associated Neoplasms Reveals Functional Host–Virus Interactions
Authors: Chakravorty Srishti , Yan Bingyu , Wang Chong , Wang Luopin , Quaid Joseph Taylor , Lin Chin Fang , Briggs Scott D. , Majumder Joydeb , Canaria D. Alejandro , Chauss Daniel , Chopra Gaurav , Olson Matthew R. , Zhao Bo , Afzali Behdad , Kazemian Majid
Published: April 2023

Table S5J-part3, expression values (transcripts per million; T.P.M.) of all genes (rows) in each sample (columns).
Supplementary Data S1, S2, and S3 from Mesenchymal Stem Cell–Mediated Delivery of an Oncolytic Adenovirus Enhances Antitumor Efficacy in Hepatocellular Carcinoma
Authors: Yoon A-Rum , Hong JinWoo , Li Yan , Shin Ha Chul , Lee Hyunah , Kim Hyun Soo , Yun Chae-Ok
Published: April 2023

Fig. S1. Efficiency of transduction of GFP-expressing Ads with different fiber types into MSCs; Fig. S2. Release profiles and intracellular viral production of HCC-oAd-WNTi from MSCs; Fig. S3. MSC killing effect of HCC-oAd-WNTi
Movie 2 from Randomly Distributed K14+ Breast Tumor Cells Polarize to the Leading Edge and Guide Collective Migration in Response to Chemical and Mechanical Environmental Cues
Authors: Hwang Priscilla Y. , Brenot Audrey , King Ashley C. , Longmore Gregory D. , George Steven C.
Published: April 2023

Movie demonstrating K14-GFP migration
Movie 1 from Randomly Distributed K14+ Breast Tumor Cells Polarize to the Leading Edge and Guide Collective Migration in Response to Chemical and Mechanical Environmental Cues
Authors: Hwang Priscilla Y. , Brenot Audrey , King Ashley C. , Longmore Gregory D. , George Steven C.
Published: April 2023

Movie demonstrating collective migration
Figure S6 from Anti–PD-L1 Treatment Results in Functional Remodeling of the Macrophage Compartment
Authors: Xiong Huizhong , Mittman Stephanie , Rodriguez Ryan , Moskalenko Marina , Pacheco-Sanchez Patricia , Yang Yagai , Nickles Dorothee , Cubas Rafael
Published: April 2023

Remodeling of the macrophage compartment is observed in responsive tumor models
Figure S5 from Anti–PD-L1 Treatment Results in Functional Remodeling of the Macrophage Compartment
Authors: Xiong Huizhong , Mittman Stephanie , Rodriguez Ryan , Moskalenko Marina , Pacheco-Sanchez Patricia , Yang Yagai , Nickles Dorothee , Cubas Rafael
Published: April 2023

EMT6 and JC tumors have different immune infiltrates, M1/M2 macrophage subset composition and IFNγ levels following treatment
Figure S2 from EZH2 Inhibitor GSK126 Suppresses Antitumor Immunity by Driving Production of Myeloid-Derived Suppressor Cells
Authors: Huang Shuo , Wang Zhongyu , Zhou Jie , Huang Jiani , Zhou Li , Luo Jing , Wan Yisong Y. , Long Haixia , Zhu Bo
Published: April 2023

GSK126 attenuates anti-tumor immunity
Figure S1 from EZH2 Inhibitor GSK126 Suppresses Antitumor Immunity by Driving Production of Myeloid-Derived Suppressor Cells
Authors: Huang Shuo , Wang Zhongyu , Zhou Jie , Huang Jiani , Zhou Li , Luo Jing , Wan Yisong Y. , Long Haixia , Zhu Bo
Published: April 2023

Effect of GSK126 on EZH2 expression and H3K27 trimethylation
Supplementary Table 1 from Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma
Authors: Slemmons Katherine K. , Yeung Choh , Baumgart Joshua T. , Juarez Jhazeel O. Martinez , McCalla Amy , Helman Lee J.
Published: April 2023

Primer sets used for qRT-PCR and MS-PCR.
Supplementary Tables from Oncogenic Properties of the Antisense lncRNA COMET in BRAF- and RET-Driven Papillary Thyroid Carcinomas
Authors: Esposito Roberta , Esposito Daniela , Pallante Pierlorenzo , Fusco Alfredo , Ciccodicola Alfredo , Costa Valerio
Published: April 2023

Table S1: List of oligonucleotide pairs. Table S2: COMET-correlated genes.
Supplementary Figure legends from Oncogenic Properties of the Antisense lncRNA COMET in BRAF- and RET-Driven Papillary Thyroid Carcinomas
Authors: Esposito Roberta , Esposito Daniela , Pallante Pierlorenzo , Fusco Alfredo , Ciccodicola Alfredo , Costa Valerio
Published: April 2023

Legends of the Supplementary Figures
Supplementary Figure 4 from Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma
Authors: Slemmons Katherine K. , Yeung Choh , Baumgart Joshua T. , Juarez Jhazeel O. Martinez , McCalla Amy , Helman Lee J.
Published: April 2023

Combination treatment in additional RMS cell lines.
Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
Authors: Shete Sanjay , Liu Hongliang , Wang Jian , Yu Robert , Sturgis Erich M. , Li Guojun , Dahlstrom Kristina R. , Liu Zhensheng , Amos Christopher I. , Wei Qingyi
Published: April 2023

Supplementary Tables 1-4, 9-16. Supplemental Table 1. Association results of SNPs with SCCHN risk with P-value {less than or equal to} 1x10-3 in the discovery dataset or with P-value {less than or equal to} 5x10-8 in the meta-analysis. Supplemental Table 2. Association results of SNPs with oral cancer risk with P-value {less than or equal to} 1x10-3 in the discovery dataset or with P-value {less than or equal to} 5x10-8 in the meta-analysis. Supplemental Table 3. Association results of SNPs with oropharynx cancer risk with P-value {less than or equal to} 1x10-3 in the discovery dataset or with P-value {less than or equal to} 5x10-8 in the meta-analysis. Supplemental Table 4. Association results of SNPs with hypopharynx and larynx cancer risk with P-value {less than or equal to} 1x10-3 in the discovery dataset or with P-value {less than or equal to} 5x10-8 in the meta-analysis. Supplemental Table 9. Association results of previously reported SNPs in the discovery dataset. Supplemental Table 10. Association results of HLA variants with overal SCCHN cancer risk with P-value {less than or equal to} 0.05 in the MDACC data. Supplemental Table 11. Association results of HLA variants with oral cancer risk with P-value {less than or equal to} 0.05 in the MDACC data. Supplemental Table 12. Association results of HLA variants with oropharyngeal cancer risk with P-value {less than or equal to} 0.05 in the MDACC data. Supplemental Table 13. Association results of HLA variants with hypo-pharyngeal and laryngeal cancer risk with P-value {less than or equal to} 0.05 in the MDACC data. Supplemental Table 14. Associations of DRB1*1301-DQA1*0103-DQB1*0603 haplotype with the risks of SCCHN and subtyp tumors. Supplementary Table 15. Correlations between standardized polygenic risk score (PRS) and the risk of oropharyngeal cancer risk in the MDACC study and OncoArray study. Supplementary table 16. Function prediction for SNPs with validated P {less than or equal to} 0.05 and meta-analysis P-value {less than or equal to} 5x10-8 with Haploreg 4.1.
Supplementary References from A Single-Step, High-Dose Selection Scheme Reveals Distinct Mechanisms of Acquired Resistance to Oncogenic Kinase Inhibition in Cancer Cells
Authors: Finn Kenneth J. , Martin Scott E. , Settleman Jeff
Published: April 2023

Full reference information for studies cited in Supplementary Table 3.
Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
Authors: Shete Sanjay , Liu Hongliang , Wang Jian , Yu Robert , Sturgis Erich M. , Li Guojun , Dahlstrom Kristina R. , Liu Zhensheng , Amos Christopher I. , Wei Qingyi
Published: April 2023

Supplementary Tables 5-8. Supplementary Table 5. Unconditional and conditional analyses of 4 low LD SNPs after clump analysis using overall SCCHN data, conditioning on any three other SNPs in the table. Supplementary Table 6. Unconditional and conditional analyses of SNPs with meta-analysis P-value < 5e-08 conditioning on the two lead SNPs (rs10462706 and rs1049055) in the two loci associated with oral cancer risk. Supplementary Table 7. Unconditional and conditional analyses of SNPs with meta-analysis P-value < 5e-08 with oropharyngeal cancer risk, conditioning on the six SNPs (rs41258944, rs28366328 rs73730372, rs9469220, rs144112342, and rs2194452) located in the two loci reported to associated with oropharyngeal cancer risk. Supplementary Table 8. Unconditional and conditional analyses of SNPs with meta-analysis P-value < 5e-08 with hypo-pharyngeal and laryngeal cancer risk, conditioning on the lead SNPs (rs14202170) at loci 18q22.
Supplementary Data 5 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Authors: Gobin Matthieu , Nazarov Petr V. , Warta Rolf , Timmer Marco , Reifenberger Guido , Felsberg Joerg , Vallar Laurent , Chalmers Anthony J. , Herold-Mende Christel C. , Goldbrunner Roland , Niclou Simone P. , Van Dyck Eric
Published: April 2023

This document contains Supplementary Table S4, which regroups the differentially expressed genes identified between the G1 and G3 groups of the Wang dataset and the gene ontology terms associated.
Supplementary Data 4 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Authors: Gobin Matthieu , Nazarov Petr V. , Warta Rolf , Timmer Marco , Reifenberger Guido , Felsberg Joerg , Vallar Laurent , Chalmers Anthony J. , Herold-Mende Christel C. , Goldbrunner Roland , Niclou Simone P. , Van Dyck Eric
Published: April 2023

This document contains Supplementary Table S2 and S3. Specifically, Table S2 lists the studied genes and documents their deregulation in GBM samples; Table S3 presents the results of the Cox regression analysis of the factors influencing PFS and OS in the Köln dataset.
Full Online Materials and Methods from A Single-Step, High-Dose Selection Scheme Reveals Distinct Mechanisms of Acquired Resistance to Oncogenic Kinase Inhibition in Cancer Cells
Authors: Finn Kenneth J. , Martin Scott E. , Settleman Jeff
Published: April 2023

More exhaustive version of the materials and methods section.
Supplementary Figure S5 from 4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer
Authors: Wang Zhiyong , Feng Xiaodong , Molinolo Alfredo A. , Martin Daniel , Vitale-Cross Lynn , Nohata Nijiro , Ando Mizuo , Wahba Amy , Amornphimoltham Panomwat , Wu Xingyu , Gilardi Mara , Allevato Michael , Wu Victoria , Steffen Dana J. , Tofilon Philip , Sonenberg Nahum , Califano Joseph , Chen Qianming , Lippman Scott M. , Gutkind J. Silvio
Published: April 2023

Supplementary Figure S5 shows A, western blot analysis of 4E-BP1 regulation by mTOR, not ERK; B, densitometry analysis of figure 3B; and C, densitometry analysis of figure 4B.
Table S3 from Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs
Authors: Porta Chiara , Consonni Francesca Maria , Morlacchi Sara , Sangaletti Sabina , Bleve Augusto , Totaro Maria Grazia , Larghi Paola , Rimoldi Monica , Tripodo Claudio , Strauss Laura , Banfi Stefania , Storto Mariangela , Pressiani Tiziana , Rimassa Lorenza , Tartari Silvia , Ippolito Alessandro , Doni Andrea , Soldà Giulia , Duga Stefano , Piccolo Viviana , Ostuni Renato , Natoli Gioacchino , Bronte Vincenzo , Balzac Fiorella , Turco Emilia , Hirsch Emilio , Colombo Mario P. , Sica Antonio
Published: April 2023

Stat1 peaks detected in p50-/- PEC stimulated with IFNγ for 2 hours as compared to WT PEC
Supplementary Data from Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs
Authors: Porta Chiara , Consonni Francesca Maria , Morlacchi Sara , Sangaletti Sabina , Bleve Augusto , Totaro Maria Grazia , Larghi Paola , Rimoldi Monica , Tripodo Claudio , Strauss Laura , Banfi Stefania , Storto Mariangela , Pressiani Tiziana , Rimassa Lorenza , Tartari Silvia , Ippolito Alessandro , Doni Andrea , Soldà Giulia , Duga Stefano , Piccolo Viviana , Ostuni Renato , Natoli Gioacchino , Bronte Vincenzo , Balzac Fiorella , Turco Emilia , Hirsch Emilio , Colombo Mario P. , Sica Antonio
Published: April 2023

supplementary figures and Materials & Methods
Supplementary Figures from Early Noninvasive Detection of Response to Targeted Therapy in Non–Small Cell Lung Cancer
Authors: Phallen Jillian , Leal Alessandro , Woodward Brian D. , Forde Patrick M. , Naidoo Jarushka , Marrone Kristen A. , Brahmer Julie R. , Fiksel Jacob , Medina Jamie E. , Cristiano Stephen , Palsgrove Doreen N. , Gocke Christopher D. , Bruhm Daniel C. , Keshavarzian Parissa , Adleff Vilmos , Weihe Elizabeth , Anagnostou Valsamo , Scharpf Robert B. , Velculescu Victor E. , Husain Hatim
Published: April 2023

The supplementary figures for "Early noninvasive detection of response to targeted therapy in non-small cell lung cancer" depict dynamic changes of ctDNA during therapy (S1), copy number changes identified in cfDNA from analyses of whole-genome data (S2), concordance between alterations observed with TEC-Seq in the plasma and clinical NGS analyses in the tumor tissue or plasma (S3), timeline of ctDNA analyses, CT assessments, and treatment response (S4), CT imaging assessments for responders and non-responders (S5), and cell-free tumor load and change in RECIST SLD (S6) for patients analyzed.
Supplementary Materials from Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition
Authors: Luo Man-Li , Zheng Fang , Chen Wenying , Liang Zhi-Mei , Chandramouly Gurushankar , Tan Jianan , Willis Nicholas A. , Chen Chun-Hau , Taveira Mateus de Oliveira , Zhou Xiao Zhen , Lu Kun Ping , Scully Ralph , Wulf Gerburg M. , Hu Hai
Published: April 2023

Supplementary Materials include six figures and two tables.
Figure S1 from Epstein–Barr Virus miRNA BART2-5p Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing RND3
Authors: Jiang Chen , Li Lei , Xiang Yan-Qun , Lung Maria Li , Zeng Tingting , Lu Jiabin , Tsao Sai Wah , Zeng Mu-Sheng , Yun Jing-Ping , Kwong Dora L.W. , Guan Xin-Yuan
Published: April 2023

Supplementary Figure 1 (a) Two EBV (-) NPC cell lines SUNE1 and HK1 and one carcinoma cell line CNE2 were infected by lentivirus to establish stable expression of BART2-5p for following study. The abundance of BART2-5p was quantified by QPCR to confirm successful gene transduction and its expression level was comparable with that in 20 primary NPC tissues. (b) CNE2 was transduced with Vector or BART2 by lentivirus to establish stable cell line. Migration or invasion assays were performed once Blasticidin selection finished. Migrated and invaded cells were counted and the number of which was shown in the bar chart. (c) Matrigel coated transwell assay was performed with CNE2 cells transiently transfected with negative control, inhibitor of BART2-3p, inhibitor of BART2-5p or both inhibitors. Invaded cells were counted for subsequent statistical analysis. (d) CNE2 transduced with Vector or BART2 were injected into the tail vein of nude mice. Lung metastasis was examined 2 months later. Cells with BART2 expression formed more and larger metastatic lesions in lung. (Left) The number of metastatic nodules on the lung surface were counted and compared statistically. (Right) (e) Lung metastasis was examined by IHC staining. As all cells were GFP labeled, they can be easily located due to brown color. Compared with the minor metastasis formed by Vector carrying cells, BART2 expressing cells developed into larger metastatic lesions. (f) In vivo imaging was used to visualize metastatic status in abdominal cavity of mice at the endpoint. Metastatic tumor with GFP florescence was visualized. (Left) Major organs were excised from sacrificed mice for examination of overt metastasis. Blue arrows indicated metastatic nodules on organ surface. (Right) (g) Slides from different organs were subjected to IHC staining. Brown color indicated GFP expression. Compared with single disseminated cancer cells found in organs of control mice, cells with BART2 expression developed into more and larger metastatic colonies in these organs. (h) Survival analysis of mice in each group during the observation period. Each group had 9 mice.
Supplementary Figures 4-7 from Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors
Authors: Beckmann Pauline J. , Larson Jon D. , Larsson Alex T. , Ostergaard Jason P. , Wagner Sandra , Rahrmann Eric P. , Shamsan Ghaidan A. , Otto George M. , Williams Rory L. , Wang Jun , Lee Catherine , Tschida Barbara R. , Das Paramita , Dubuc Adrian M. , Moriarity Branden S. , Picard Daniel , Wu Xiaochong , Rodriguez Fausto J. , Rosemarie Quincy , Krebs Ryan D. , Molan Amy M. , Demer Addison M. , Frees Michelle M. , Rizzardi Anthony E. , Schmechel Stephen C. , Eberhart Charles G. , Jenkins Robert B. , Wechsler-Reya Robert J. , Odde David J. , Huang Annie , Taylor Michael D. , Sarver Aaron L. , Largaespada David A.
Published: April 2023

Figure S4. Shows ARHGAP36 expression in mouse and human neural tissue. Figure S5. Shows characterization of ARHGAP36 and Megf10 in C17.2 cells Figures S6-S7 show mechanistic analysis of FOXR2 in C17.2 and HSC1L cells
Figure S8 from The Lymphatic Cell Environment Promotes Kaposi Sarcoma Development by Prox1-Enhanced Productive Lytic Replication of Kaposi Sarcoma Herpes Virus
Authors: Choi Dongwon , Park Eunkyung , Kim Kyu Eui , Jung Eunson , Seong Young Jin , Zhao Luping , Madhavan Shrimika , Daghlian George , Lee Hansuh H. , Daghlian Patill T. , Daghlian Saren , Bui Khoa , Koh Chester J. , Wong Alex K. , Cho Il-Taeg , Hong Young-Kwon
Published: April 2023

Interaction of Prox1 and RTA was not detected in K-BECs
Supplementary Figure 3 from Whole Genome–Derived Tiled Peptide Arrays Detect Prediagnostic Autoantibody Signatures in Non–Small-Cell Lung Cancer
Authors: Yan Yuanqing , Sun Nan , Wang Hong , Kobayashi Makoto , Ladd Jon J. , Long James P. , Lo Ken C. , Patel Jigar , Sullivan Eric , Albert Thomas , Goodman Gary E. , Do Kim-Anh , Hanash Samir M.
Published: April 2023

Top two networks encompassing proteins with three or more hot spots among cases
Supplementary Fig 3 from Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma
Authors: Wang Jun , Merino Diana M. , Light Nicholas , Murphy Brian L. , Wang Yong-Dong , Guo Xiaohui , Hodges Andrew P. , Chau Lianne Q. , Liu Kun-Wei , Dhall Girish , Asgharzadeh Shahab , Kiehna Erin N. , Shirey Ryan J. , Janda Kim D. , Taylor Michael D. , Malkin David , Ellison David W. , VandenBerg Scott R. , Eberhart Charles G. , Sears Rosalie C. , Roussel Martine F. , Gilbertson Richard J. , Wechsler-Reya Robert J.
Published: April 2023

Figure S3 shows lineage tracing of Blbp+ progenitors in the choroid plexus of the lateral ventricle and 4th ventricle of the mouse brain.
Supplementary Fig 2 from Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma
Authors: Wang Jun , Merino Diana M. , Light Nicholas , Murphy Brian L. , Wang Yong-Dong , Guo Xiaohui , Hodges Andrew P. , Chau Lianne Q. , Liu Kun-Wei , Dhall Girish , Asgharzadeh Shahab , Kiehna Erin N. , Shirey Ryan J. , Janda Kim D. , Taylor Michael D. , Malkin David , Ellison David W. , VandenBerg Scott R. , Eberhart Charles G. , Sears Rosalie C. , Roussel Martine F. , Gilbertson Richard J. , Wechsler-Reya Robert J.
Published: April 2023

Figure S2 shows H&E staining on Atoh1-Cre CPC.
Supplementary legend from Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells
Authors: Takeda Mitsunobu , Koseki Jun , Takahashi Hidekazu , Miyoshi Norikatsu , Nishida Naohiro , Nishimura Junichi , Hata Taishi , Matsuda Chu , Mizushima Tsunekazu , Yamamoto Hirofumi , Ishii Hideshi , Doki Yuichiro , Mori Masaki , Haraguchi Naotsugu
Published: April 2023

Supplementary Figure legend
Supplementary Table from Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells
Authors: Takeda Mitsunobu , Koseki Jun , Takahashi Hidekazu , Miyoshi Norikatsu , Nishida Naohiro , Nishimura Junichi , Hata Taishi , Matsuda Chu , Mizushima Tsunekazu , Yamamoto Hirofumi , Ishii Hideshi , Doki Yuichiro , Mori Masaki , Haraguchi Naotsugu
Published: April 2023

Blood test and serial transplantation of the tumors at the end of the 30 days of each treatment.
Table S4 from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa
Authors: Harlemon Maxine , Ajayi Olabode , Kachambwa Paidamoyo , Kim Michelle S. , Simonti Corinne N. , Quiver Melanie H. , Petersen Desiree C. , Mittal Anuradha , Fernandez Pedro W. , Hsing Ann W. , Baichoo Shakuntala , Agalliu Ilir , Jalloh Mohamed , Gueye Serigne M. , Snyper Nana Yaa F. , Adusei Ben , Mensah James E. , Abrahams Afua O.D. , Adebiyi Akindele O. , Orunmuyi Akin T. , Aisuodionoe-Shadrach Oseremen I. , Nwegbu Maxwell M. , Joffe Maureen , Chen Wenlong C. , Irusen Hayley , Neugut Alfred I. , Quintana Yuri , Seutloali Moleboheng , Fadipe Mayowa B. , Warren Christopher , Woehrmann Marcos H. , Zhang Peng , Ongaco Chrissie M. , Mawhinney Michelle , McBride Jo , Andrews Caroline V. , Adams Marcia , Pugh Elizabeth , Rebbeck Timothy R. , Petersen Lindsay N. , Lachance Joseph
Published: April 2023

Comprehensive list of cancer-associated loci with African allele frequencies and PBS scores. This dataset includes a total of 2,477 unique markers yielding 3,557 disease or trait associations
Supplementary Figure. S2 from Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells
Authors: Takeda Mitsunobu , Koseki Jun , Takahashi Hidekazu , Miyoshi Norikatsu , Nishida Naohiro , Nishimura Junichi , Hata Taishi , Matsuda Chu , Mizushima Tsunekazu , Yamamoto Hirofumi , Ishii Hideshi , Doki Yuichiro , Mori Masaki , Haraguchi Naotsugu
Published: April 2023

The high magnification of immunohistochemical staining
Table S1 from Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma
Authors: Mastrella Giorgia , Hou Mengzhuo , Li Min , Stoecklein Veit M. , Zdouc Nina , Volmar Marie N.M. , Miletic Hrvoje , Reinhard Sören , Herold-Mende Christel C. , Kleber Susanne , Eisenhut Katharina , Gargiulo Gaetano , Synowitz Michael , Vescovi Angelo L. , Harter Patrick N. , Penninger Josef M. , Wagner Ernst , Mittelbronn Michel , Bjerkvig Rolf , Hambardzumyan Dolores , Schüller Ulrich , Tonn Jörg-Christian , Radke Josefine , Glass Rainer , Kälin Roland E.
Published: April 2023

APLN co-expressed genes are enriched for angiogenesis in glioblastoma subtypes