bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental effect of collagen-containing medication on skin morphology
Authors: Sel’skaya B N , Musina L A , Kamilov F Kh
Published: December 2017

Aim. To evaluate morphological skin changes of the experimental animals after intradermal injection of collagenous medication. Methods. The histological and histochemical methods (staining with hematoxylin and eosin, by Van-Gieson, Mallory and Foot method) were used to study the skin of mature female rats in the area of intradermal injection of collagen preparation «Kollost» by using mesotherapy method in 2, 4, 21 and 37 days. Murine skin was compared between experimental and control groups, in which the rats had solution of dextrose (glucose) injected intradermally. Results. On days 2-4 after the injection, inflammatory reaction was weak in the form of cellular infiltration along the needle stick. Numerous macrophages resorbing fibrous elements of the medication were determined in the injection zone. On days 7-14 fibroblasts proliferation, occurrence of argyrophilic thin newly-formed collagenous fibres and significant content of glycosaminoglycanes in the granulation tissue were revealed. By the 21-st day of the experiment following the injection, the dermal plate of the skin had become more dense due to the formation of thicker collagenous bundles in regeneration zones. When impregnated by silver nitrate they became yellow-brown that was indicative of fibre maturity. On day 37, the collagen fibers of the injected preparation in the injection zone were not detected in free unsubstituted form. The skin had a typical structure. The signs of stimulation of regeneration processes were not revealed in the skin of rats from the control group following the glucose solution injection. Conclusion. The collagenous preparation did not cause any pronounced inflammatory processes in the skin following intradermal injection to mature female rats; the fibrous structures of «Kollost» are resorbed by macrophages and substituted by the collagenous fibres integrating into the tissues; the processes are accompanied by stimulation of proliferation of structural elements of the skin connective tissue.
Endogenous sodium pump inhibitors: common pathogenetic mechanisms of impaired glucose tolerance and preeclampsia
Authors: Reznik V A , Fedorova O V , Tapil’skaya N I , Bagrov A Ya
Published: December 2017

Aim. Study of the influence of sodium chloride overconsumption by pregnant rats with induced diabetes mellitus on the synthesis of marinobufagenin and Na/K-ATPase activity. Methods. The study was performed on 72 female Sprague Dawley rats. Type 2 diabetes mellitus was induced by administration of 65 mg/kg streptozotocin on day 4 after birth. Increased intake of salt was achieved by replacement of drinking water with 1.8% sodium chloride solution on days 12 to 19 of pregnancy. Results. In intact rats, pregnancy was associated with a two-fold increase of marinobufagenin level in the blood and mild impairment of glucose tolerance. Pregnant rats with induced diabetes mellitus apart from fetal macrosomia exhibited greater impairment of glucose tolerance and higher levels of marinobufagenin compared to those in intact pregnant animals. Compared to healthy pregnant rats, salt supplementation for laboratory animals with diabetes was associated with an increase in systolic blood pressure, decreased fetal and placental weight, five-fold elevation of marinobufagenin excretion, and in 42% - with inhibition of Na/K-ATPase activity in erythrocytes. In nonpregnant rats, pre-treatment with anti-marinobufagenin antibodies produced an exaggerated increase of blood levels of glucose and insulin in oral glucose tolerance test. Conclusion. Marinobufagenin is an important factor of pathogenesis of both preeclampsia and diabetes mellitus, and regulation of glucose tolerance may be one of the physiological functions of endogenous cardiotonic steroids.
Cooperación transfronteriza en la EUROACE: Extremadura (2007-2014) = Cross-border cooperation in the EUROACE: Estremadura (2007-2014)
Authors: Campesino Fernández Antonio José
Published: December 2017

En el presente artículo procedemos al análisis de las políticas, planes y proyectosde cooperación transfronteriza entre 2007-2014, por cuanto las actividades correspondientes al periodo 1990-2006 fueron ya publicadas en nuestra primera aportación de 2008. En los últimos siete años se solapa el desarrollo del Programa de Cooperación Transfronteriza España-Portugal (POCTEP, 2007-2013) con la creación y puesta en funcionamiento de la Eurorregión Alentejo-Centro-Extremadura (EUROACE, 2009-2014). El POCTEP, sucesor de los sucesivos Programas Operativos INTERREG, fue aprobado por la Comisión Europea el 25 de octubre de 2007, con el objetivo de promover el desarrollo de las zonas fronterizas entre España y Portugal, reforzando las relaciones económicas y las redes de cooperación existentes desde 1990. El 18 de febrero de 2010 se creó la Comunidad de Trabajo de la EUROACE Alentejo-Centro-Extremadura, que conforma la primera Eurorregión tripartita en la raya hispano-portuguesa. Una estructura sin personalidad jurídica que sirve de plataforma para que entidades públicas y privadas de las tres regiones desarrollen programas de cohesión socioeconómica y cooperación territorial transfronteriza. El artículo analiza ejes estratégicos, actividades y proyectos en la Raya extremeña de la EUROACE, con especial énfasis en los relativos a la explotación de los recursos territoriales, paisajísticos y culturales, con fines turísticos.In this article we proceed to the analysis of policies, plans and cross-border cooperation projects between 2007-2014 because the activities for the period 1990-2006 were already published in our first contribution of 2008. In the last seven years overlaps the development of Cross Border Cooperation Programme Spain-Portugal (POCTEP, 2007-2013) with the creation and operation of the Euroregion Alentejo-Centre-Estremadura (EUROACE 2009-2014). The POCTEP, successor of successive Programs Operating INTERREG, was approved by the European Commission on 25 October 2007, with the aim of promoting the development of border areas between Spain and Portugal, strengthening economic relations and networking of existing cooperation since 1990. On 18 February 2010 the Working Community of the EUROACE Alentejo-Centre-Estremadura, which forms the first tripartite Euroregion in the Spanish-Portuguese stripe was created. A structure without legal personality that serves as a platform for public and private entities in the three regions to develop programs of economic and social cohesion and cross-border territorial cooperation. The article analyzes strategic priorities, activities and projects in Estremadura EUROACE stripe, with special emphasis on those relating to the exploitation of land, landscape and cultural resources for tourism.
Territorio, patrimonio y turismo en la Raya de Castilla y León = Territory, heritage and tourism in the Raya of Castile and Leon
Authors: Hortelano Mínguez Luis Alfonso , Martín Jiménez María Isabel
Published: December 2017

La línea fronteriza de Castilla y León con Portugal tiene una longitud de 349 kilómetros donde se amolda una franja compuesta por 37 términos municipales de las comarcas agrarias de Vitigudino y de Ciudad Rodrigo en Salamanca y de Sanabria, Aliste y Sayago en Zamora. Este territorio rayano comprende una superficie de 2.366,27 km2 y, si tomamos como referencia la escala comarcal, se amplia hasta los 10.203,80 km2. Como consecuencia de la localización periférica y “de borde”, de su evolución histórica y de la aplicación de un modelo económico sostenible, esta zona fronteriza mantiene inalterado un variado medio natural y un rico patrimonio cultural material e inmaterial. Algunas de las áreas han sido reconocidas con una figura de protección por sus valores ambientales y otro tanto ha ocurrido con la riqueza arqueológica e histórico-artística al incluirse en el catálogo administrativo de Bienes de Interés Cultural. En el periodo finisecular del XX y en el umbral del siglo XXI, gracias a la puesta en valor de los recursos endógenos asociados al patrimonio territorial, han surgido propuestas de actividades turísticas agrupadas en las modalidades de ecoturismo y turismo de naturaleza, cultural y activo con el objeto de buscar alternativas laborales y potenciar el desarrollo socioeconómico.The border between the Spanish region of Castile and Leon and Portugal has a length of 349 km. The border area on the Spanish side totals 37 municipalities in the rural districts of Vitigudino and Ciudad Rodrigo in the province of Salamanca and the districts of Sanabria, Aliste and Sayago in the province of Zamora. This borderland has an area of 2,366.27 square km, which if the area of the border districts would be tabled, would total 10,203.80 square km. As a consequence of its peripheral situation on the Raya (edge), its history and the application of a model of sustainable development the varied natural environment and the rich material and nonmaterial cultural heritage of this border area have remained unchanged. Some zones have administratively been recognized because of their environmental or archeological value or their historical-artistic wealth. As such they are included in the official catalogue of Bienes de Interés Cultural (Goods of Cultural Interest). Due to the recognition of the value of endogenous resources linked to territorial heritage, at the end of the twentieth and the beginnings of the twenty-first centuries proposals have been made to foster tourism. In order to diversify employment and enforce socioeconomic development, these proposals are centered on eco, nature, cultural and active tourism.
El patrimonio en Extremadura: un mecanismo para la cooperación transfronteriza = The heritage in Estremadura: a tool for the cross border cooperation
Authors: Rengifo Gallego Juan Ignacio , Sánchez Martín José Manuel
Published: December 2017

El patrimonio cultural y natural de Extremadura se caracteriza por su abundancia, diversidad y amplia distribución territorial. Desde la década de los ochenta del siglo pasado la administración regional ha sido la encargada de diseñar políticas y estrategias dirigidas a su protección y uso social. En este artículo procedemos a realizar una radiografía, con carácter general, del patrimonio cultural y natural de Extremadura con la finalidad de evaluar el papel que éste ha jugado en la cooperación transfronteriza entre Extremadura y las regiones portuguesas de Alentejo y Centro. En el análisis patrimonial se tienen en cuenta, especialmente, los bienes inscritos en la lista del Patrimonio Mundial de la UNESCO (Cáceres, Mérida y Guadalupe), los Bienes de Interés Cultural (261) y los espacios naturales que tienen algún nivel de protección en sus diferentes categorías (Red de espacios naturales protegidos, red natura 2000 y espacios protegidos por organismo internacionales). Asimismo, se analiza con especial interés la distribución del patrimonio por los 19 municipios de frontera, de los que 9 se distribuyen por la provincia de Badajoz y 10 por la de Cáceres. Por último, llevamos a cabo un repaso de los proyectos de cooperación aprobados en el ámbito del POCTEP (2007-2013).The cultural and natural heritage of Estremadura is characterized by its abundance, diversity and wide territorial distribution. Since the eighties of the last century the regional administration has been commissioned to design policies and strategies for social protection and use. In this article we proceed to perform an X-ray, in general, the cultural and natural heritage of Extremadura in order to assess the role it has played in cross-border cooperation between Estremadura and the Portuguese regions of Alentejo and Centre. In the income analysis are taken into account, especially the properties inscribed on the World Heritage list of UNESCO (Caceres, Merida and Guadalupe), the Cultural Interest (261) and natural spaces that have some level of protection different categories (network of protected areas, Natura 2000 and protected by international body spaces). Also it discussed with particular interest the distribution of assets by the 19 border municipalities, of which 9 are distributed by the province of Badajoz and 10 of Caceres. Finally, we conducted a review of the cooperation projects approved in the field of POCTEP (2007-2013).
Effect of probiotics on constipation in children
Authors: Jose Santhosh , K. Mohamad Ismael
Published: December 2017

Background: Constipation in children is a common problem. A constipated child has infrequent bowel movements or hard, dry stools. This is a randomized controlled trial to find the relationship between probiotics and constipation in children. Methods: This study was a randomized, controlled blinded trial conducted in Department of Paediatric. This was done during a period of January 2014 to January 2016 conducted in 50 patients. The patients were divided into two groups randomly namely group A who received lactulose plus protexin daily and group B who received lactulose plus placebo alone. Results: Males were 15 (60%) and females were 10 (40%) in group A and in group B, males were 10 (40%) and females were 15 (60%). Faecal incontinence was in 13 (52%) in group A and in 10 (40%) in group B. Abdominal pain was in 16 (64%) in group A and was in 14 (56%) in group B. The stool frequency and consistency improved significantly. There was a significant improvement in fecal incontinence and abdominal pain in the Group A, and at the end of the fourth week, this difference was not significant and there was improvement significantly in weight gain. Side effects were not seen in the during the treatment. Conclusions: This study shows that there was a positive effect of probiotics on constipation in children.
The Effect of Polysaccharides Peptides Ganoderma Lucidum to Aortic Foam Cell Count and Lipid Profile in Type 2 Diabetic Model Rattus Norvegicus Strain Wistar
Authors: Sargowo Djanggan , Wihastuti Titin Andri , Sukotjo Cathrine Theodora , Anjani Prasanti Mahesa , Handayani Olivia , Adrian Liemena Harold
Published: December 2017

BACKGROUND: Type 2 Diabetes Mellitus (DM) is one of dominant factors in cardiovascular deaths and induces endothelial dysfunction. A definite sign of endothelial dysfunction is foam cells formation derived from oxidized LDL. This study was conducted to determine effect of Polysaccharides Peptides (PsP) Ganoderma lucidum to foam cell counts and lipid profile in diabetic model rats with high-fat diet.METHODS: Treatment group was categorized to negative control, positive control, DM-50, DM-150, and DM-300. Type 2 DM induced by Streptozotocin. PsP is administered with predetermined doses on each treatment’s group (50, 150, and 300 mg/kgBW) for 12 weeks. Measurements of foam cell count were held after obtaining rat’s aorta. To assess lipid profile, blood sample was taken from the rat's heart. Data analyzed by One-way ANOVA and Post Hoc Tukey tests.RESULTS: The administration of Ganoderma lucidum PsP to diabetic model rats provided a significant difference in lowering foam cell (p=0.017; CI 95%). It also gave significant difference between levels of each lipid components (Total Cholesterol, Trygliceride, LDL and HDL) in at least two treatment groups (p=0.010; CI 95%). Based on Post Hoc Tukey tests, the relationship between administration of PsP and foam cell is significant (p=0.002).CONCLUSION: PsP has antioxidant and anti-inflammatory effect in type 2 DM model Rattus norvegicus strain wistar, which can inhibit atherosclerosis and endothelial damage process. Further studies are necessary to evaluate the benefits of PsP as an adjuvant therapy in management of diabetic dyslipidemia.KEYWORDS: PsP, Ganoderma lucidum, foam cell, lipid profile, DM
Caspase Inhibitor Diminishes Caffeic Acid-induced Apoptosis in Osteosarcoma Cells
Authors: Sandra Ferry , Hudono Karina Febriani , Putri Amelia Astriani , Putri Chantika Amardhia Paramita
Published: December 2017

BACKGROUND: Caffeic acid has been shown to induce apoptosis in MG63 osteosarcoma cells. Along with the apoptotic induction, caffeic acid was shown to activate caspase-8, -9 and -3. However, the role of caspase in mediating caffeic acid-induced apoptosis in MG63 cells are not clear yet. In this study, caspase role was further investigated by inhibiting caspase activity in the caffeic acid-induced apoptosis system in the MG63 cells.METHODS: MG63 cells were cultured, starved, pretreated with/without Z-VAD FMK and treated with/without 10 µg/mL caffeic acid. To quantify the number of apoptotic MG63 cells, Sub-G1 method was performed. The caffeic acid-induced apoptotic morphology was confirmed with 4',6-diamidino-2-phenylindole (DAPI) staining and Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. Meanwhile, to detect apoptotic underlying mechanism, immunoblotting was performed to detect caspase-8, -9 and -3.RESULTS: MG63 cells were significantly induced into apoptosis with the treatment of 10 µg/mL caffeic acid for 48 hours. However, pretreatment of 100 µM Z-VAD-FMK, a pan caspase inhibitor, for 2 hours, the percentage of apoptotic MG63 cells was significantly diminished. The apoptotic phenomenon induced by caffeic acid as well as the inhibition of Z-VAD-FMK were confirmed by DAPI staining and TUNEL assay. Cleaved caspase-8, -9 and -3 were formed markedly upon the treatment of caffeic acid. Pretreatment of 100 µM Z-VAD-FMK could inhibit the cleaved caspase-8, -9 and -3.CONCLUSION: Taken together, caffeic acid has the potential to induce apoptosis in MG63 cells, specifically through the caspase signaling pathway.KEYWORDS: caffeic acid, apoptosis, MG63, caspase, Z-VAD FMK
Telomeres and Telomerase in The Aging Heart
Authors: Meiliana Anna , Dewi Nurrani Mustika , Wijaya Andi
Published: December 2017

BACKGROUND: Aging per se is a risk factor for reduced cardiac function and heart diseases, even when adjusted for aging-associated cardiovascular risk factors. Accordingly, aging-related biochemical and cell-biological changes lead to pathophysiological conditions, especially reduced heart function and heart disease.CONTENT: Telomere dysfunction induces a profound p53-dependent repression of the master regulators of mitochondrial biogenesis and function, peroxisome proliferator-activated receptor gamma coactivator (PGC)-1a and PGC-1b in the heart, which leads to bioenergetic compromise due to impaired oxidative phosphorylation and ATP generation. This telomere-p53-PGC mitochondrial/metabolic axis integrates many factors linked to heart aging including increased DNA damage, p53 activation, mitochondrial, and metabolic dysfunction and provides a molecular basis of how dysfunctional telomeres can compromise cardiomyocytes and stem cell compartments in the heart to precipitate cardiac aging.SUMMARY: The aging myocardium with telomere shortening and accumulation of senescent cells restricts the tissue regenerative ability, which contributes to systolic or diastolic heart failure. Moreover, patients with ion-channel defects might have genetic imbalance caused by oxidative stress-related accelerated telomere shortening, which may subsequently cause sudden cardiac death. Telomere length can serve as a marker for the biological status of previous cell divisions and DNA damage with inflammation and oxidative stress. It can be integrated into current risk prediction and stratification models for cardiovascular diseases and can be used in precise personalized treatments.KEYWORDS: aging, telomere, telomerase, aging heart, mitochondria, cardiac stem cell
Indícios do civismo na cultura do grupo escolar costa carneiro: o jornal o estudante Orleanense (1949-1973)
Authors: Rabelo Giani , Massiroli Vanessa
Published: December 2017

Este artigo é resultado de uma pesquisa realizada no campo da História da Educação, em que se teve como objetivo analisar os ideais de civismo disseminados por meio do jornal O Estudante Orleanense, e que fizeram parte da cultura do Grupo Escolar Costa Carneiro (Orleans, SC) entre os anos 1949 e 1973. De modo específico, buscou-se demonstrar de que forma esse civismo foi divulgado antes e durante a Ditadura Civil-Militar. Os resultados demonstraram que a produção do jornal resistiu a diversas reformas políticas, reproduzindo em suas páginas ações e intenções que colaboravam para a formação de cidadãos patriotas, sendo um instrumento importante no processo de construção da cultura escolar do educandário.
A literatura na seção infantil da biblioteca pública do Paraná: a hora do conto
Authors: De Araujo Karina Valim , Orlando Evelyn de Almeida
Published: December 2017

Este artigo é resultado de um estudo realizado na “Hora do conto” da seção infantil da Biblioteca Pública do Paraná (BPP). Com o objetivo de analisar a formação do leitor ainda na infância, partiu-se da problemática de como a “Hora do conto” pode contribuir para tal formação. Utilizaram-se como instrumentos de pesquisa a observação e a análise de fotos, constituindo-se como registros documentais dentro de uma abordagem de pesquisa qualitativa. As principais referências teóricas foram: Arroyo (2008), Zilberman (2003), Abramovich (1995) e Chartier (1989, 2001). Os resultados indicam que as práticas educativas ocorrem de maneira lúdica e que a “Hora do conto” tornou o espaço um polo de encontro cultural, fomentando o interesse pela leitura que, por se realizar no âmbito de uma biblioteca, coloca as crianças em contato direto com o universo literário.
A exploração de brinquedos por crianças em experiências lúdicas na educação infantil
Authors: Nicolielo Maria Elisa , Sommerhalder Aline
Published: December 2017

Neste estudo objetivou-se compreender o modo como o brinquedo foi explorado por crianças da educação infantil em momentos de brincadeira livre em sala, e que funções foram atribuídas para esse objeto lúdico. Por meio da abordagem qualitativa, procedeu-se observação participante com 13 diários de campo, com discussão à luz de aporte teórico. Entre os resultados, verificou-se que o brinquedo, tanto o industrializado quanto o objeto transformado em brinquedo, fez-se consideravelmente presente nas brincadeiras, oportunizando o enriquecimento das experiências pelas crianças. Destacou-se necessária a qualificação da mediação docente no que se refere às manifestações de estereótipos de gênero em brincadeiras, a oferta de outros ambientes para brincar e a atenção pedagógica na disponibilização dos objetos lúdicos, a fim de contribuir para os processos de criação, exploração e enriquecimento das experiências das crianças.
Gestão da educação: das políticas federais à gestão municipal
Authors: Bugança Natália da Silva , Ruiz Maria José Ferreira
Published: December 2017

No texto tem-se o objetivo de identificar as principais políticas para a gestão da educação implementadas pelo Governo federal entre os anos 2003 e 2011 e analisar como essas políticas impactaram a gestão das escolas municipais. Utilizam-se como procedimentos metodológicos a pesquisa bibliográfica, a análise documental e as entrevistas. Conclui-se que essas políticas interferem na gestão municipal, por possibilitarem a aquisição de obras e equipamentos, mas intervêm de forma tênue nas escolas, visto que as diretoras demonstraram pouco conhecimento sobre elas e uma preocupação maior com questões administrativas e pedagógicas do cotidiano escolar.
Editorial
Authors: Chaves Priscila Monteiro , Feldkercher Nadiane
Published: December 2017

Editorial
La entidad de los vínculos de familia según la Corte Suprema de Chile, para efectos de revocar las resoluciones de expulsión de inmigrantes
Authors: Mondaca Miranda Alexis
Published: December 2017

En el presente trabajo se estudia la jurisprudencia de la Corte Suprema, máximo tribunal de justicia de Chile. En concreto, se analizan las sentencias recaídas sobre las acciones de amparo deducidas por los inmigrantes, con las que se intenta dejar sin efecto las medidas de expulsión que los afectan, emanadas de la autoridad administrativa. El fundamento de las acciones de amparo está constituido por el daño que la ejecución de la expulsión puede causar a los nexos familiares que han constituido.
Znaczenie konsumpcji w życiu studentów. Analiza porównawcza opinii studentów krajów Grupy Wyszehradzkiej
Authors: Żak Monika
Published: December 2017

Przedmiotem niniejszego artykułu jest analiza wyników badań przeprowadzonych wśród studentów krajów Grupy Wyszehradzkiej. Jest to fragment większego projektu badawczego, który obejmował zagadnienia dotyczące świadomości ekonomicznej młodego pokolenia. Stosunek do zakupów i konsumpcji w ogólności jest jednym z elementów świadomości ekonomicznej. Zaprezentowane zostaną konkluzje dotyczące postaw konsumenckich studentów, które wbrew obiegowym opiniom – jak wykazały badania – są dosyć racjonalne. Młode pokolenie podchodzi do kwestii konsumpcji z namysłem, dostosowując zakres, częstotliwość i sposoby zaspokajania swoich różnorakich potrzeb do środków i możliwości, jakimi dysponuje.
Między strategią a przypadkiem – postrzeganie karier przez młodych pracowników
Authors: Piekarska Aleksandra
Published: December 2017

W artykule autorka podejmuje rozważania dotyczące roli karier nieliniowych w początkowym okresie życia zawodowego człowieka. Kariery nieliniowe nie przebiegają systematycznie i w jednolitych sferach działalności zawodowej, ich przebieg nie jest więc łatwy do przewidzenia. Tego typu kariery wpisują się w przestrzeń współczesnego globalnego rynku pracy i stanowią rozwiązania pozwalające na dostosowywanie się do płynnej rzeczywistości. Podstawowe zagadnienia stawiane przez autorkę dotyczą tego, czy realizowane kariery nieliniowe przez młodzież i młodych dorosłych: 1) są postrzegane jako sposób na eksplorację; 2) są wykorzystywane do budowania portfela doświadczeń zawodowych przez młodych ludzi; 3) na ile są świadomie planowane, a na ile są wynikiem przypadku lub przymusu ekonomicznego; 4) jaki jest stosunek młodych ludzi do nieliniowego charakteru kariery, czy tego rodzaju ścieżka zawodowa jest uznawana jako zwiększająca szanse na rynku pracy, czy wręcz przeciwnie. Rozważania literaturowe zamieszczone w pierwszej części artykułu zostały wsparte wynikami badań ankietowych przeprowadzonych wśród 162 studentów studiów niestacjonarnych. Punktem wyjścia prezentowanych badań są wyniki wcześniejszych analiz eksploracyjnych, które pozwoliły na wyodrębnienie dwóch głównych modeli karier nieliniowych. Wyodrębnione modele są wykorzystane w badaniach prezentowanych w artykule do określenia typów karier respondentów oraz ich oceny przez badanych pod względem między innymi przydatności na rynku pracy. Przebieg karier respondentów jest analizowany także pod kątem intencjonalności podejmowanych działań związanych z pracą w kontekście zarządzania własną karierą.
Subiektywna jakość życia a zasoby kapitału ludzkiego mieszkańców miast poprzemysłowych
Authors: Michalska-Żyła Agnieszka
Published: December 2017

Celem artykułu jest określenie znaczenia głównych zasobów kapitału ludzkiego (wykształcenia, zdrowia fizycznego i samopoczucia psychicznego) w kształtowaniu subiektywnej jakości życia mieszkańców pięciu miast poprzemysłowych położonych w Polsce, Rosji, na Litwie, na Węgrzech i w Turcji oraz wskazanie podobieństw i różnic, jakie występują w tym względzie między poszczególnymi ośrodkami. Podjęta zostanie próba odpowiedzi na pytanie, który z czynników w większym stopniu różnicuje poziom jakości życia badanych oraz jakie podobieństwa i różnice występują między badanymi zbiorowościami. Zaprezentowane rezultaty badań słaniają do wniosku, iż wybrane zasoby kapitału ludzkiego stanowią raczej słaby model wyjaśniający różnice w subiektywnej jakości życia badanych zbiorowości, choć poziom oddziaływania tego układu zmiennych jest różny w zbiorowościach poszczególnych miast. Zasobów kapitału ludzkiego nie można zatem traktować jako uniwersalnych predykatorów subiektywnej jakości życia w grupie badanych miast poprzemysłowych. Komponentem kapitału ludzkiego najsilniej różnicującym poziom ocen własnego życia było samopoczucie psychiczne, jednak jego znaczenie także było zróżnicowane.
Effect of drip fertigation on pigeonpea [Cajanus cajan (L.) Millsp] – A review
Authors: Loganathan Vimalendran , Nandhini D. Udhaya , Latha K. R.
Published: December 2017

Food legumes are important source of protein in the diets of a large section of vegetarian population in the developing countries in general and India in particular. Even though India has the largest area under pulses in the world, the average productivity is relatively low and the production is not adequate to meet the demand. For increasing the productivity of the pulses key inputs viz., water, seeds and nutrients need to be applied in the right quantity to enhance the production. The water use efficiency is increased through micro irrigation in the form of drips and sprinklers. Drip irrigation can be considered as an efficient irrigation system since it causes wetting of the soil only and maintain optimum moisture content in the root zone. It also offers several water management advantages like timely application of water and water supply. Micro irrigation provides many unique agronomic, water and energy conservation benefits that address many of the challenges facing irrigated agriculture, now and in the future
Transcriptome profiling: methods and applications- A review
Authors: Rani Bibha , Sharma V. K.
Published: December 2017

Global transcriptional profiling is a powerful tool that can expose expression patterns to define cellular states or to identify genes with similar expression patterns. In recent years, transcriptome profiling has been widely used to understand the genetic regulation of a particular cell type. Transcriptome is defined as a full range of messenger Ribonucleic acid (RNA) molecule expressed by an organism. In other words a transcriptome represents the small percentage of genetic code that is transcribed into RNA molecules. It can offer valuable information on the significant biological processes behind the maintenance of the functionality of the cell. Transcriptomics provides fundaments for more definitively designed studies and guidance to select the genes for functional studies. The technology for the study of the transcriptome is not dependent on any prior knowledge of the genes expressed in the cells. However, with regards to the administration and interpretation of the enormous data provided by transcriptome profiling challenges remain.. Four methods have been reviewed here that is, Microarray technology, Serial Analysis of Gene Expression (SAGE), RNA sequencing (RNA-Seq) and Massively Parallel Signature Sequencing (MPSS). The use of these technologies to analyse the expressed transcripts in several prokaryotic and eukaryotic genomes has revealed the high complexity of transcriptomes.
Pensamiento pedagógico colombiano: Martín Restrepo Mejía. Una mirada a sus conceptos de pedagogía, infancia, maestro y escuela
Authors: Jiménez Becerra Absalon
Published: December 2017

El artículo se enmarca en el inicio de una línea de investigación: Historia del pensamiento pedagógico colombiano. Esta propuesta busca rescatar el trabajo de una serie de intelectuales de la educación, quienes, por medio de sus razonamientos, intervenciones, conferencias, ensayos, y libros han aportado al ejercicio reflexivo de la educación local y regional. Esta primera investigación rescata la vida y obra de uno de los primeros intelectuales de la educación colombiana; Martín Restrepo Mejía (1865-1935). Se enfatiza especialmente en sus reflexiones y representaciones de la pedagogía, la infancia, el maestro, y la educación escolar.

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Contextualización Idioma Maya Kaqchikel

Contextualizadora: Myrna Lucy Xajpot Sanain

Ministerio de Educación de Guatemala

RUK’U’X SAMAJ

 

Re jun peraj samaj re ntikir rikin rucholajem rukanoxik na'oj: Rutzijol ch’ob’onïk pa ruwi rub’eyal tijonïk richin colombiano. Re jun na’oj re’ nrajo chi nikol ri kina’oj ri yalan yechobon pa ruwi’ tijonïk, ruma nkiya’ kina’oj chupan ri kitzijonïk, ri kisamaj, ri kitz’ib’anik nkiya’ richin yoj ch’ob’on pa ruwi’ tijonïk pa taq kitinamit akuchi e k’owi’. Chupam re jun nab’ey na’oj re, xkikanöj rukolik k’ik’aslem ri nab’ey taq chob’onela’ pa ruwi ri tijonïk richin ri tinamït Colombia;  Martín Restrepo Mejía (1865-1935). Janta pe niya’ox runataxik chupam kich’ob’oj chuqa’ toq yech’o pa ruwi’ rub’eyal tijonïk, pa kiwi’ ri ak’wala’, pa kiwi’ ri tijonela’, chuqa’ ri tijonïk  pa tijob’äl jay.

 Ruk’u’x tan tzij: na’oj richin rub’eyal tijojïk;  rub’eyal tijonïk; pa kiwi’ ak’wala’; pa kiwi’ tijonela’; chupam ri tijob’äl; Na’oj samaj tijonela’ Hisula.
Enhancement of Regeneration Efficiency through Callus Induction Media Using 2,4-Dicholorophenoxyacetic acid in Indica Rice (Oryza sativa L. var. Ciherang)
Authors: Azizah Kunti Anis , Restanto Didik Pudji , Sugiharto Bambang
Published: December 2017

Indica rice variety Ciherang is the most planted variety in Indonesia, but the micropropagation technique is restricted because it is known has low regeneration frequency and included as recalcitrant cultivar for tissue culture and tranformation activities. One of solution to resolve that problem is developing a technique of somatic embryogenesis in callus of ciherang rice cultivar. The aims of study were to determine medium composition for inducting embryogenic callus in Ciherang rice and to know the effectivity of rice regeneration using callus as explant. The methods were included induction of embryogenic callus in callus induction media (CIM) containing MS basal, Proline 600 mg/l, Casein Hidrolisat 300 mg/l, phytagel 2,5 g/l, BAP 0.25 mg/l, sukrosa 30 %, and 2,4-D in different concentration, from 2,4-D 0 mg/l as control (CIM 1), 2,4-D 2 mg/l (CIM 2), 2,4-D 3 mg/l (CIM 3), and 2,4-D 4 mg/l (CIM 4). It then be continued to regenerate the calli in RM 1 medium containing MS basal, NAA 0,2 mg/l, Kinetin 2 mg/l, Agarose 10 g/l, and sukrosa 30 %, pH 5,8 for six days in dark and RM2 medium containing MS basal , NAA 0,2 mg/l, Kinetin 2 mg/l, Agarose 8 g/l, sukrosa 30 %, pH 5,8 in light room. Results showed CIM 4 medium using 2,4-D 4 mg/l gave optimum result in calli induction with procentage 57,63% and CIM 3 using 2,4-D 3 mg/l gave optimum result in embryonic calli induction with procentage 53,63%. Result of embryonic calli gave regeneration frequency procentage is 9,6%. The total planlet obtained after five weeks old in regeneration medum were 11 planlets ready for aclimatization.

Keywords: Somatic embryo, Indica rice (Oryza sativa L. var. Ciherang), Callus
Combination of Organic Fertilizer and Biological Agent for Pest Control Spodoptera exigua of Plant Onion in Gending, Probolinggo
Authors: Agustini Yusia , Purwatiningsih P. , Sulistyanto Didik
Published: December 2017

Onion is one of lowland vegetables commodity that has been long cultivated intensively by farmers in Indonesia. Probolinggo is one of the regions which give considerable contribution of producing onion to the national needs. In an effort to increase production, onion farmers in Probolinggo mostly relies on external supply in the form of artificial chemicals (fertilizers and pesticides). However, the using of artificial chemicals can cause pollution and damage the environment. So that utilization of biological agents and organic fertilizers which are environmentally friendly can become other solutions to increase the yield of onion production. Based on this case, it is very important in efforts to increase production of onion by combining organic fertilizers to enrich the content of organic matter in the soil with biological agents in tackling pests attack. Based on the research results in application of combining organic fertilizers granules plus NEP and biological agents Heterorhabditis sp. in District Gending Probolinggo shows that : 1. reducing the population of pests Spodoptera exigua up to 72.260%. 2. improving onion plant growth more optimal. From the result, it shows that the combination of organic fertilizer granule plus biological agents and NEP Heterorhabditis sp. (P2A1) is more effective than the combination of the others.

Keywords: onion, biological agents, spodoptera exigua
Diversity and Density Gastropods in Mangrove Forest of Si Runtoh Beach, Baluran National Park
Authors: Siwi Fitri Retnananing , Sudarmadji S. , Suratno S.
Published: December 2017

The mangrove forest is one of the coastal ecosystems of unique and productive. One of the animals that can be found in the mangrove ecosystem are gastropods. Gastropods constitute the largest class of the phylum of mollusks. Gastropods can usually be found in tidal areas, because these animals have a very high adaptability. The existence of mangrove gastropods in the area can be used as an indicator that the mangrove on the beach working properly or not. Diversity and density of research conducted in the mangrove forest Si Beach Runtoh Baluran National Park in February until April 2014 during a low tide maximal. The sampling method used in this research is the method of transects made per station. Transect length is 100 m, the total number of stations is 8, and the distance between the station 25 m. In one station consists of 8 transects, transects 15 m spacing, each transect consists of three plots measuring 5 m x 5 m. The results showed a diversity of mangrove Gastropods Si Beach Runtoh Baluran National Park is H '= 4,180 were classified as moderate while gastropods density obtained is 0.832 individu/m2.

Keywords: gastropods, diversity, density
ANALISIS KESEDIAAN MEMBAYAR (WILLINGNESS TO PAY) BERAS CERDAS CV AN – NAHLAH DI KABUPATEN JEMBER
Authors: Rahayu Anggraini Dwi , Hapsari Triana Dewi , Adam Julian
Published: December 2017

This study was aimed to identify : (1) consumer characteristic related to their willingness to pay for beras cerdas CV An – Nahlah in Jember ; (2) maximum average willingness to pay of beras cerdas CV An – Nahlah consumer in Jember ; (3) factors affecting consumer willingness to pay for beras cerdas CV An – Nahlah in Jember. The method used is analytical descriptive method. Sample taken purposively using incidental sampling technique. The data analyzed using descriptive analysis and multiple linier regression. The study showed that (1) the characteristics of beras cerdas CV An – Nahlah consumer was related to their willingness to pay are; female, has a bachelor degree, include in adult group, married employed, average income Rp 1.500.000 – Rp 3.000.000 monthly their willingness to pay ranged between Rp 17.001 – Rp 21.000 per 800 gram. (2) maximum average consumer willingness to pay is Rp 20.075 per 800 gram. (3) factors influenced consumer willingness to pay are; age, gender, married status, education,  job, and monthly income.
Análise do conhecimento dos profissionais de saúde sobre o uso de oxigenoterapia em um hospital universitário de Fortaleza-CE
Authors: Barreto Patriciane Hedwiges , Silva Francisca Soraya Lima , Vasconcelos Renata Dos Santos de , Sales Raquel Pinto , Vasconcelos Thiago Brasileiro de , Nogueira Andréa Da Nóbrega Cirino , Holanda Marcelo Alcantara
Published: December 2017

Objetivo: analisar o conhecimento dos profissionais de saúde a respeito do uso da oxigenoterapia. Métodos: estudo quantitativo e transversal realizado em um Hospital Universitário da cidade de Fortaleza-CE. Participaram do estudo médicos, enfermeiros e fisioterapeutas. Para a coleta de dados utilizou-se um questionário semiestruturado contendo dados a respeito da formação acadêmica, tempo de experiência e conhecimento acerca da oxigenoterapia. Resultados: a amostra foi composta por 50 profissionais, com média de idade de 28,1 ± 10,9 anos, em sua maioria mulheres 80% (n = 40). Com relação à profissão, 44% (n = 22) possuem graduação em enfermagem, seguidas pela fisioterapia 32% (n = 16) e medicina 22% (n = 11). As indicações da oxigenoterapia com significância estatística são: hipoxemia, dessaturação e doença respiratória. Doença pulmonar obstrutiva crônica (DPOC), pneumotórax e hiperoxemia foram pontuadas como principais contraindicações, em relação aos efeitos adversos os mais prevalentes foram intoxicação, ressecamento e hipercapnia. O catéter nasal, máscara de Venturi, máscara com reservatório e macronebulização foram os tipos de oferta de oxigênio (O2) mais pontuados (p < 0,05). Conclusão: diante do exposto observamos que pode haver déficit em relação ao conhecimento dos profissionais de saúde a respeito do uso de oxigênio suplementar.
Obesidade infantil: revisão de literatura
Authors: Aragão Sofia Goersch Andrade
Published: December 2017

A obesidade é um distúrbio crônico que resulta do aumento de gordura proveniente de um desequilíbrio no balanço energético. Vem acometendo cada vez mais crianças e adolescentes e está associada com graves consequências cardiovasculares e psicossociais. Com o objetivo de ampliar conhecimentos que favoreçam a prevenção e diagnóstico precoce de seus fatores de risco foram analisados estudos sobre obesidade infantil visando à promoção da saúde dessa faixa etária. A obesidade infantil se desenvolve, na maioria das vezes, da predisposição genética, associada a fatores comportamentais e ambientais. Verifica-se a grande importância da participação familiar, da prática de atividade física rotineira e do consumo de alimentos saudáveis e nutritivos desde o início da vida no combate à obesidade. A relevância deste agravo e suas consequências reforçam a necessidade de conscientização da prevenção de seus fatores de risco por meio de ações efetivas na primeira infância para inibir as tendências de crescimento da obesidade nesta faixa etária e provavelmente na fase adulta, dentre as quais se destacam as ações de puericultura, a avaliação do crescimento linear, assim como orientações regulares sobre controle e combate da obesidade aos pais e cuidadores, por serem estes os responsáveis pelo estado nutricional e comportamento alimentar infantil.
O Brasil que desejamos
Authors: Garcia José Huygens Parente
Published: December 2017

O Sistema Verdes Mares (SVM) apresenta hoje a 47a edição de uma das comendas mais prestigiadas do nosso estado. Tudo começou com a ousadia e empreendedorismo de um jovem que, em 1951, acreditou que tinha chegado o momento de sua cidade entrar na era do gás de botijão. Em seguida, vieram o sistema verdes mares de comunicação, agroindústria, liderança nacional em distribuição de água mineral, fabricação de eletrodomésticos, dentre outras atividades. Um homem a frente de seu tempo, Edson Queiroz implantou no Ceará um dos mais sólidos grupos empresariais do país, gerando riquezas e milhares de empregos. Com o objetivo de homenagear, de maneira expressiva, aqueles que se destacaram e deram sua contribuição ao desenvolvimento do Ceará, em seus diferentes setores de atuação, Edson Queiroz criou, em 1971, o Troféu Sereia de Ouro. Dona Yolanda Queiroz conduziu com maestria essa solenidade, por quase 5 décadas. Esta é a segunda solenidade sem a sua presença e a primeira após a perda recente e lastimável do chanceler Airton Queiroz. O chanceler esteve a frente, por 35 anos, da UNIFOR, Universidade de Fortaleza, uma das mais prestigiadas Universidades Brasileiras. O chanceler Airton Queiroz deixa um grande legado na educação, arte e cultura. Continuando o ciclo da vida, como bem descreve o poeta português Fernando Pessoa, uma nova geração assume o Grupo Edson Queiroz. Seguindo os exemplos dos patriarcas, com trabalho, desprendimento, honestidade e comprometimento com a causa social, a prosperidade estará garantida.
Penfigoide gestacional: relato de caso e a importância do diagnóstico precoce
Authors: Botelho Karine Paschoal , Barroso Caroline Braga , Costa Igor Santos , Gonçalves Heitor De Sá , Pontes Maria Araci
Published: December 2017

O penfigoide gestacional é uma rara dermatose bolhosa autoimune específica da gravidez. Acredita-se que anticorpos ataquem antígenos epidérmicos específicos e provoquem a separação da junção dermoepidérmica da pele e a formação de bolhas. O quadro em geral se inicia com placas eritematosas pruriginosas periumbilicais com posterior disseminação pelo corpo e evolução para lesões bolhosas. Acomete principalmente primíparas no segundo ou terceiro trimestre e costuma responder bem ao tratamento com corticoide sistêmico. Exame histopatológico e imunofluorescência direta são fundamentais para o diagnóstico. Há risco de efeitos adversos fetais, como baixo peso ao nascer e parto prematuro. Relatamos um caso de uma paciente com quadro exuberante no final do terceiro trimestre com excelente resposta ao tratamento e com nascimento de recém-nascido a termo e saudável.
Treatment, Palliative Care or Euthanasia? Comparing End of Life Issues in Veterinary and Human Medicine
Authors: Eyre-Pugh Ruth E.
Published: December 2017

This is the second of a series of two papers comparing the end of life issues in human and veterinary medicine. We outline the main differences between human and animal patients such as patient communication, finance and ‘conflicts of interest’ between animal, owner and veterinarian. We discuss striking similarities between human and veterinary issues such as assessing quality of life and the primary role of the attending veterinarian or doctor being the welfare and care of the patient. This paper takes the form of an ethical argument in favour of allowing euthanasia in human medicine, by providing insights into end of life issues for humans from an independent veterinary perspective. Veterinary surgeons are well trained in the ethics of euthanasia and put it to good use in the best interest of their animal patients. Doctors in the UK are limited and unwilling to put forward a case for the option of euthanasia for those patients who face a slow and agonizing death. With advances in medical science being able to significantly prolong the dying process, autonomy for the patient demands a review of the law regarding patient choice in the UK.
Calculation of Resonant Frequency for a Microstrip Antenna with Vertical Slots Using Applying Adaptive Network-Based Fuzzy Inference System
Authors: Abbasi Layegh Mahmood , Ghobadi Changiz , Nourinia Javad
Published: December 2017

This paper attempts at applying adaptive network-based fuzzy inference system (ANFIS) for analysis of the resonant frequency of a microstrip rectangular patch antenna with two equal size slots which are placed on the patch vertically. The resonant frequency is calculated as the position of slots is shifted to the right and left sides on the patch. As a result , the antenna resonates at more than one frequency . Commonly, machine algorithms based on artificial neural networks are employed to recognize the whole resonant frequencies. However ,they fail to estimate the resonant frequencies correctly as in some cases variations are not very sensible and the resonant frequencies overlap each other . It can be concluded that artificial neural networks could be replaced in such designs by the adaptive network-based fuzzy Inference system due to its high approximation capability and much faster convergence rate.
High-Resolution Crystal Structure of RpoS Fragment Including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila
Authors: Zhang Nannan , Chen Xiaofang , Gong Xiaojian , Li Tao , Xie Zhiyuan , Hameed Muhammad Fazal , Ge Honghua
Published: December 2017

Legionella pneumophila RpoS (LpRpoS) is an alternative sigma factor of RNA polymerase (RNAP) essential for virulence and stress resistance. To investigate the mechanism of RpoS in the intracellular pathogen L. pneumophila, we determined the high-resolution crystal structure of the LpRpoS (residues 95-194) containing a partial region 1.2 and region 2. The structure of LpRpoS (residues 95-194) reveals that the conserved residues are critical for promoter melting, DNA and core RNAP binding. The differences in regulatory factor binding site between Escherichia coli RpoS and LpRpoS suggest that LpRpoS may employ a distinct mechanism to recruit alternative regulatory factors controlling transcription initiation.