bluuebunny/crossref_metadata_2025 huggingface dataset:
Accuracy of Mathematical Models and Process Simulators for Predicting the Performance of Gas-Separation Membranes
Authors: Alqaheem Yousef
Published: November 2024

A membrane unit for gas separation is not available in most process simulators, and therefore it needs to be built manually. However, the developed units are based on assumptions, and the system is solved numerically. The accuracy of these models with industrial data is rarely discussed in the literature, but it is needed to confirm the reliability of process simulators. In this work, the membrane unit was developed in two different simulation software such as the commercial UniSIM® and the freeware CAPE-OPEN to CAPE-OPEN (COCO). In UniSIM®, the membrane module was built internally using a component splitter, spreadsheet, and adjust functions. In COCO, the membrane unit was developed by program coding with the external computational software, Scilab. The developed membrane units were assessed with field data for fuel gas conditioning. Results show that the membrane unit was easier to build in UniSIM® but when calculating the flowrate and composition of all compounds at the permeate and retentate sides, UniSIM® gives an error of 17.4% while COCO gives a slightly lower error of 17.1%. The high error was related to the effects of plasticization and concentration polarization, which were not taken into consideration in the mathematical model.
Media Matters: How Information Release Shapes Monkeypox Vaccination Willingness
Authors: Wang Huan , Wu Nan
Published: November 2024

Despite the growing body of evidence addressing the reasons behind vaccine hesitancy, the positive role of media as a key environmental factor influencing vaccination, as well as its function in publicizing and encouraging vaccination, has been less thoroughly explored. This study focuses on the context of the current Monkeypox epidemic, examining the influence of media release channels and message framing on the public’s willingness to receive the Monkeypox vaccine. The findings are empirically validated through a survey experiment conducted in China. The study reveals that both media channels—traditional TV media, official online media, and user-generated media—and media content framings, specifically thematic and episodic, significantly impact the public’s willingness to be vaccinated against Monkeypox. Notably, in the context of this public health event, individuals were more inclined to trust the episodic framing of traditional TV media and the thematic framing of official online media. Compared to thematic framing, episodic framing generally enhances respondents’ willingness to vaccinate. Furthermore, user-generated media exhibited a more negative effect on vaccination intentions during the Monkeypox epidemic, particularly when combined with episodic framing. Heterogeneity analysis indicated a significant difference in the effectiveness of official online media based on audience identity (student vs. non-student), with the student group showing a preference for official online media channels. The findings underscore the importance of public health communication in carefully selecting media release types and message framings. Additionally, it is crucial to consider audience heterogeneity and to employ differentiated communication methods to enhance the effectiveness of vaccine promotion.
Graphene-Based Fiber Materials for Gas Sensing Applications: State of the Art Review
Authors: Vu Susanna , Siaj Mohamed , Izquierdo Ricardo
Published: November 2024

The importance of gas sensors is apparent as the detection of gases and pollutants is crucial for environmental monitoring and human safety. Gas sensing devices also hold the potential for medical applications as health monitoring and disease diagnostic tools. Gas sensors fabricated from graphene-based fibers present a promising advancement in the field of sensing technology due to their enhanced sensitivity and selectivity. The diverse chemical and mechanical properties of graphene-based fibers—such as high surface area, flexibility, and structural stability—establish them as ideal gas-sensing materials. Most significantly, graphene fibers can be readily tuned to detect a wide range of gases, making them highly versatile in gas-sensing technologies. This review focuses on graphene-based composite fibers for gas sensors, with an emphasis on the preparation processes used to achieve these fibers and the gas sensing mechanisms involved in their sensors. Graphene fiber gas sensors are presented based on the chemical composition of their target gases, with detailed discussions on their sensitivity and performance. This review reveals that graphene-based fibers can be prepared through various methods and can be effectively integrated into gas-sensing devices for a diverse range of applications. By presenting an overview of developments in this field over the past decade, this review highlights the potential of graphene-based fiber sensors and their prospective integration into future technologies.
Colorectal Cancer in Elderly Patients: Insights into Presentations, Prognosis, and Patient Outcomes
Authors: Shalata Walid , Gluzman Alexander , Man Sofia , Cohen Ahron Yehonatan , Abu Jama Ashraf , Gothelf Itamar , Tourkey Lena , Neime Ala Eddin , Abu Juma’a Ali , Peri-Hanania Keren , Machluf Oshri , Shoham Levin Gal , Shalata Sondos , Hayadri Ahab , Abu Zeid Ez El Din , Abu Yasin Nashat , Meirovitz Amichay , Yakobson Alexander
Published: November 2024

Background and Objectives: Colorectal cancer (CRC) ranks as the third most prevalent cancer globally and is the third leading cause of cancer-related deaths. In 2020 alone, there were over 1.9 million new cases of CRC and nearly 0.9 million deaths worldwide. The incidence and outcomes of CRC exhibit significant geographical and temporal variations, largely influenced by diverse risk factors among populations. Recognizing the prognostic factors and the presenting symptoms of CRC, a leading global cancer with high mortality, can enhance early detection and thereby improve clinical outcomes. Materials and Methods: This retrospective, observational study analyzed 724 CRC elderly patients aged 70 and over (median age 80, 53.17% male), treated at a single center. Data on demographics, clinical characteristics, and outcomes were collected. Overall survival was analyzed using Kaplan–Meier curves, with stratification based on tumor location, disease staging, lymph node involvement, and family history. Results: Our study encompassed all CRC cases treated with surgery and systemic therapies (chemotherapy or biological agents) from July 2002 to September 2020. We focused on comparing prognosis between left-sided and right-sided CRC, as well as rectal cancer. We found that left-sided CRC demonstrated a superior prognosis compared to rectal cancer (p = 0.0022). Furthermore, among patients with CRC, tumors originating in the rectum were associated with worse outcomes compared to those arising in both the right and left colon, regardless of disease stage (p = 0.0049). Additionally, a family history of CRC was associated with poorer prognosis, impacting both metastatic (p = 0.0022) and localized disease (p = 0.035). The main symptoms prompting patients to start an investigation of CRC were abdominal pain (31.49%), anemia (18.08%), rectal bleeding (hematochezia) (17.82%), change in bowel habits (9.94%), and weight loss (7.60%). Conclusions: This study provides valuable insights into the symptoms prompting initial investigation and the prognostic factors associated with CRC in an elderly population with varied characteristics. It underscores the need for increased vigilance in recognizing key symptoms and the importance of personalized treatment strategies tailored to these prognostic factors.
Optimizing Scan Range in Computed Tomography of Kidneys, Ureters, and Bladder: A Retrospective Study on Reducing Overscanning
Authors: Bin Owien Ali , Alenazi Khaled , Abanomy Ahmad , Almanaa Mansour , Alarifi Mohammad , Alahmad Haitham
Published: November 2024

Background and Objectives: Computed tomography of the kidneys, ureters, and bladder (CT KUB) is essential for evaluating urinary stones but also exposes patients to significant radiation. The scanning field should be minimized to only the necessary area to limit this radiation exposure. This study aims to assess the extent of CT KUB overscanning in renal colic procedures and identify the appropriate vertebral level for starting CT KUB scans. Materials and Methods: A retrospective analysis of 299 adult patients who underwent CT KUB examinations for kidney stone assessment was performed. To assess overscanning, the number of excess slices above the pole of the highest kidney and under the pubic symphysis was measured on the axial image of each patient. To allow for potential human error, a maximum acceptable level of overscanning was set at 10%. Results: This study found that only 31% of the scans met the target of less than 10% of overscanning superior to the highest kidney and inferior to the pubic symphysis. In comparison, overscanning was present in 69% of the scans, mainly at a superior level, resulting in higher radiation exposure for patients. Conclusions: A significant number of the scans exhibited unnecessary overscanning beyond the highest kidney, prompting us to propose using the upper border of the T10 vertebral body as a potential reference point to establish the upper margin for a CT KUB scan. This study suggests using T10 and the pubic symphysis as reliable landmarks to accurately determine the scan length. Starting CT KUB scans from the T10 vertebral body to the pubic symphysis allows for imaging of the entire urinary tract, minimizing unnecessary overscanning and reducing patient irradiation.
Health Benefits of Epigallocatechin Gallate and Forskolin with a Special Emphasis on Glaucoma and Other Retinal Diseases
Authors: Rusciano Dario
Published: November 2024

This review highlights the therapeutic potential of epigallocatechin gallate (EGCG) and forskolin in managing retinal diseases, with a focus on glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy. EGCG, a potent polyphenol from green tea, exhibits significant antioxidant, anti-inflammatory, and neuroprotective effects, making it a promising candidate for reducing oxidative stress and inflammation in ocular tissues. Forskolin, a diterpene from Coleus forskohlii, increases cyclic AMP (cAMP) levels, which helps lower intraocular pressure (IOP) and provides neuroprotection. Both compounds target critical pathways involved in retinal disease progression, including oxidative stress, mitochondrial dysfunction, and inflammation, offering complementary therapeutic benefits. This review consolidates preclinical and clinical studies, highlighting the potential of EGCG and forskolin as adjunctive or alternative treatments for retinal diseases. Future research should explore the synergistic effects of these compounds, particularly in combination therapies aimed at addressing multiple pathogenic mechanisms in retinal health.
Application of Surface Complexation Modeling to Investigate the Mechanism of Cu2+ Adsorption on TiO2, Al2O3, and SiO2 Under High Surface Coverage
Authors: Piasecki Wojciech , Lament Karolina
Published: November 2024

We have shown that the adsorption of Cu2+ ions on various metal oxides, depending on the pH of the solution, can be described assuming the formation of only two surface complexes with surface hydroxyl groups SOH: SOCu(OH) and SOCu+. Using an ion-selective electrode for Cu2+, we determined the adsorption edges, i.e., the dependence of the amount of adsorbed metal expressed as a percentage depending on the solution pH for three oxides: TiO2, Al2O3, and SiO2. The measurements were carried out with high surface coverage where the ratio of the adsorption sites/copper ions in the system were from 2 to 3, depending on the oxide. Simultaneously, with the adsorption edge, the hydrogen surface charge density and the electrokinetic potential of the oxide particles were measured as a function of pH. These three types of experimental data were fitted all together using the surface complexation model (2-pK TLM). In modeling, it was not necessary to consider the precipitation of Cu(OH)2 on the oxide surface to obtain good agreement with the data. Additionally, it was shown that the presence of charged surface species SOCu+ (about 10% of total adsorbed copper) was crucial to fit the data for zeta potential.
Synthesis and Characterization of Na-P1 (GIS) Zeolite Using Rice Husk
Authors: Novembre Daniela , Gimeno Domingo , Marinangeli Lucia , Tangari Anna Chiara , Rosatelli Gianluigi , Ciulla Michele , di Profio Pietro
Published: November 2024

This work deals with the synthesis of Na-P1 (GIS) zeolite using rice husk as the starting material, instead of the more expensive chemicals currently used in the industry (i.e., Na aluminates and Na silicates). Rice husk is calcined at the temperature of 550 °C to obtain rice husk ash. Na-P1 is synthesized starting from rice husk ash, NaOH, and NaAlO2 by a protocol involving the mixing of a seed gel and a feedstock gel. Two synthesis runs are carried out at ambient pressure at the temperature of 110 °C by fixing the SiO2/Al2O3 ratio at 3.5 and 5.3, respectively. The synthesized products have been identified as well as the experiments developed by X-ray diffraction and scanning electron microscopy. Then, the most successful synthesized powders were also characterized by infrared spectroscopy, Raman spectroscopy, specific surface area (BET), and differential thermal analysis. The cell parameters are calculated using the Rietveld method. The combined Rietveld and reference intensity ratio methods allows us to exclude the presence of impurities and residual amorphous phase in the conducted experiments. Testing rice husk as a source of amorphous silica in the synthesis of Na-P1 represents both economic and environmental advantages. The high yields and the results of the experiment open the way for the transfer to an industrial production scale.
Increased Trypanocidal Activity of the Salinomycin Derivative Ironomycin Is Due to ROS Production and Iron Uptake Impairment
Authors: Steverding Dietmar , Rushworth Stuart A. , Hurle Georgina R. , Antoszczak Michał , Sulik Michał , Huczyński Adam , Tyler Kevin M.
Published: November 2024

Salinomycin and its derivatives display promising anti-proliferating activity against bloodstream forms of Trypanosoma brucei. The mechanism of trypanocidal action of these compounds is due to their ionophoretic activity inducing an influx of sodium cations followed by osmotic water uptake, leading to massive swelling of bloodstream-form trypanosomes. Generally, higher trypanocidal activities of salinomycin derivatives are associated with higher cell swelling activities. Although ironomycin (C20-propargylamine derivative of salinomycin) and salinomycin showed identical cell swelling activities, ironomycin was 6 times more trypanocidal than salinomycin, and the 50% growth inhibition (GI50) values were 0.034 μM and 0.20 μM, respectively. However, when bloodstream-form trypanosomes were incubated with ironomycin in the presence of vitamin E and ammonium ferric citrate, the trypanocidal activity of the compound was reduced to that of salinomycin (GI50 = 0.21 μM vs. GI50 = 0.20 μM). In addition, vitamin E was found to decrease the trypanocidal activity of ironomycin much more than ammonium ferric citrate (GI50 = 0.18 μM vs. GI50 = 0.042 μM). Moreover, ironomycin caused a reduction in the uptake of the iron-carrier protein transferrin mediated by a downregulation of the transferrin receptor and led to the accumulation and sequestering of iron(II) in the parasite’s lysosome, triggering an increase production of reactive oxygen species (ROS). These results suggest that the increased trypanocidal activity of ironomycin can be mainly attributed to an increased ROS production and, to a lesser extent, an impairment in iron uptake.
Virus Removal from Real Wastewater as an Environmental Management Approach
Authors: Gomes João , Domingues Eva , Frasson Danilo , Martins Rui C. , Matos Ana Miguel
Published: November 2024

The increased presence of resistant microorganisms in water promotes the need for supplementary measures to mitigate the water source’s contamination. Traditional treatments are inefficient in wastewater management at removing some emerging contaminants. Corbicula fluminea, an invasive species, can be used in the treatment due to their resistance and biofiltration capacity, working as a pest management strategy. In this study, this bivalve was used to promote the virus disinfection from the municipal wastewater treatment plant (MWTP) that enters (influent) and after the secondary treatment (effluent leaving the plant). JC virus, norovirus (GI, GII), and hepatitis A (HAV) were identified. C. fluminea promoted norovirus GI and GII removal after 72 h and a slight decrease in the JC virus concentration. These results prove the potential of this pest management approach to be used in virus removal. Furthermore, infectivity assays using mengovirus confirmed the correlation between the presence of the genome detected by PCR and the infectious virus particles. This highlights the potential of PCR as a reliable indicator of the infectious virus’s presence. However, such an infectivity assay proved that even when PCR results are undetectable, a reduced number of viruses may remain viable and able to infect susceptible cells in culture.
A Review of the Fabrication of Pinhole-Free Thin Films Based on Electrodeposition Technology: Theory, Methods and Progress
Authors: Gao Zike , Jiang Yuze , Meng Yao , Du Minshu , Liu Feng
Published: November 2024

Pinhole defects in thin films can significantly degrade their physical and chemical properties and act as sites for electrochemical corrosion. Therefore, the development of methods for the preparation of pinhole-free films is crucial. Electrodeposition, recognised for its efficiency and cost-effectiveness, shows great potential for applications in electrochemistry, biosensors, solar cells and electronic device fabrication. This review aims to elucidate the role of nucleation and growth models in understanding and optimising the electrodeposition process. Key parameters, such as crystal structure, orientation, surface morphology and defect control, are highlighted. In addition, the causes of pinhole defects, the effects of impurities and the potential and electrolyte composition on the deposited films are discussed. In particular, methods for minimising pinhole defects and two exemplary cases for a compact layer in relatively large-scale perovskite solar cells and nano-scale ultramicroelectrodes are discussed, exploring the influence of surface morphology, thickness and fabrication size under current common film preparation experiments. Finally, the critical aspects of controlled preparation, theoretical and technological advances, and the ongoing challenges in the field are provided.
Nanoimprinted Polymeric Structured Surfaces for Facilitating Biofilm Formation of Beneficial Bacteria
Authors: Liu Yuyan , Ferrer-Florensa Xavier , Sternberg Claus , Kempen Paul , Schift Helmut , Gram Lone , Taboryski Rafael
Published: November 2024

Initial studies indicate that structured polymer surfaces can support the attachment and biofilm formation of bacteria and thereby provide enhanced positive effects of beneficial bacteria, for instance in biocontrol in aquacultures. In this study, we demonstrate a test platform to further explore the surface topography for bacterial attachment and biofilm growth. It is based on a cyclic olefin copolymer (COC) materials platform, and nanoimprint technology was used for the replication of microstructures. The use of nanoimprint technology ensures precise micropattern transfer, enabling easy prototyping. Further, the process parameters of the mold preparation and nanoimprinting are discussed, with the purpose of optimizing the polymer pattern profile. This study has the potential to identify promising surfaces for biofilm growth of beneficial bacteria.
SIGKD: A Structured Instance Graph Distillation Method for Efficient Object Detection in Remote Sensing Images
Authors: Liu Fangzhou , Zhao Wenzhe , Qi Haoxiang , Zhou Guangyao
Published: November 2024

In the realm of remote sensing image object detection compression distillation, establishing an efficient method for instance feature knowledge transfer between teacher and student models holds paramount importance. To this end, this paper introduces an innovative deep structured instance graph distillation method that endeavors to delve into the underlying information between instance features, thereby optimizing detection performance. Specifically, our proposed method incorporates feature instances and their relations into a graph-based structure (SIG). In this graph, feature instances serve as the nodes, while the relations between them serve as the edges. This structure enables us to capture both the individual significance of each feature instance and their collective influence within the context. Furthermore, in the experiment, we found that the index of some dense and small-target objects did not improve much because the edge assembly generated by a large number of background feature nodes in the SIG module inhibited the loss. To address the perennial imbalance between foreground and background features, we introduce an adaptive background feature mining strategy. Through carefully calibrated weights, this strategy effectively extracts and integrates background information, thereby minimizing noise interference in detection results and augmenting the expressive capacity of foreground features. We achieved state-of-the-art results on both the challenging DIOR and DOTA datasets, with the two-stage Oriented RCNN-based student Resnet18 model achieving a 73.23 mAP on the DOTA benchmark, close to the teacher Resnet101’s 76.16. In addition, on the DIOR dataset, the student Resnet18 based on the two-stage Faster RCNN achieved 70.13 mAP, higher than the baseline 66.31, and the student Resnet50 achieved 72.28, higher than the teacher’s 72.25.
Automated Stock Volume Estimation Using UAV-RGB Imagery
Authors: Goswami Anurupa , Khati Unmesh , Goyal Ishan , Sabir Anam , Jain Sakshi
Published: November 2024

Forests play a critical role in the global carbon cycle, with carbon storage being an important carbon pool in the terrestrial ecosystem with tree crown size serving as a versatile ecological indicator influencing factors such as tree growth, wind resistance, shading, and carbon sequestration. They help with habitat function, herbicide application, temperature regulation, etc. Understanding the relationship between tree crown area and stock volume is crucial, as it provides a key metric for assessing the impact of land-use changes on ecological processes. Traditional ground-based stock volume estimation using DBH (Diameter at Breast Height) is labor-intensive and often impractical. However, high-resolution UAV (unmanned aerial vehicle) imagery has revolutionized remote sensing and computer-based tree analysis, making forest studies more efficient and interpretable. Previous studies have established correlations between DBH, stock volume and above-ground biomass, as well as between tree crown area and DBH. This research aims to explore the correlation between tree crown area and stock volume and automate stock volume and above-ground biomass estimation by developing an empirical model using UAV-RGB data, making forest assessments more convenient and time-efficient. The study site included a significant number of training and testing sites to ensure the performance level of the developed model. The findings underscore a significant association, demonstrating the potential of integrating drone technology with traditional forestry techniques for efficient stock volume estimation. The results highlight a strong exponential correlation between crown area and stem stock volume, with a coefficient of determination of 0.67 and mean squared error (MSE) of 0.0015. The developed model, when applied to estimate cumulative stock volume using drone imagery, demonstrated a strong correlation with an R2 of 0.75. These results emphasize the effectiveness of combining drone technology with traditional forestry methods to achieve more precise and efficient stock volume estimation and, hence, automate the process.
A Comparison of the Performance of the Pre-Ozonation Process and the Use of Coagulants with Ozone in the Removal of Algae from Surface Water
Authors: Mohammadalimirza Shahrestanaki Homa , Hassani Amirhesam , Javid Amirhossein , Torabian Ali
Published: November 2024

Purifying surface water in moderate-humid climates is challenging due to high levels of organic compounds and diatom algae, which can produce toxic substances. A new method involving chitosan and ferric chloride coagulants, along with pre-ozonation, shows promise for improving water quality. The study examined various conditions, including pH levels and concentrations of chitosan (20–500 mg/L) and ferric chloride (5–100 mg/L), as well as the pH of reaction mixtures (3–11) and ozone concentrations (2–8 mg/L). Optimal results were achieved at a pH of 10 for both coagulants, with 500 mg/L chitosan and 75 mg/L ferric chloride. A pH of 7 for the reaction mixture and an ozone concentration of 8 mg/L were most effective. The pre-ozonation process alone can eliminate 72% of algae, while combining ozone with chitosan and ferric chloride achieved diatom removal rates of 77% and 79%, respectively. These findings highlight the effectiveness of using lower ozone concentrations in conjunction with coagulants for water purification.
Critical patient care: the impact of humanization tools
Authors: Santos Bárbara Oliveira , Souza Victor Calebe de Oliveira , Santos Karen Aparecida dos , Sousa Dayanne Batista Bezerra de
Published: November 2024

Humanization in critical patient care within Intensive Care Units (ICUs) is essential to provide patient-centered care, respecting dignity and emotional needs. This study aims to identify, analyze, and synthesize the tools used for the humanization of critical patient care and assess their impact on intensive care through an integrative literature review. Searches were conducted in the PubMed, SciElo, and Lilacs databases using descriptors such as "Humanization of Care," "Health Strategies," "Critical Care," and "Intensive Care." Articles published between 2014 and May 2024, available in full text, were included. The study selection was assisted by the Rayyan software, following PRISMA criteria. The results highlight tools such as therapeutic toys, toy libraries, effective communication, personalized care, emotional and psychological support, and the creation of a welcoming environment. These tools contribute to improved care quality, greater patient and family satisfaction, shorter hospital stays, and fewer complications. Ongoing implementation of humanized practices and continuous healthcare professional training are essential for improving ICU care.
Family engagement strategies in palliative care: overcoming challenges
Authors: Souza Amanda Gomes de , Silva Umbelina Raiene da , Yoshioca Giovanna Akemi , Bittencourt Cristiane Dias , Alves Camila dos Santos Moreno Rodrigues , Reis Gabriela Torino dos , Lino Amanda Martins , Matias Luiza Malosti , Nunes Natália Abou Hala
Published: November 2024

Objective: To investigate the main difficulties faced by family members in the process of engaging in palliative care and to identify effective strategies for preventing and alleviating suffering. Method: This is an integrative review, using the Scientific Electronic Library Online (SCIELO) and the Latin American and Caribbean Health Sciences Literature (LILACS) databases, with the descriptors integrative palliative care, palliative nursing at the end of life, and palliative care. The inclusion criteria were full-text articles available in Portuguese, published in the last five years. Results: The main difficulties identified were lack of knowledge, difficulty in acceptance, and psychosocial perspective. The strategies mentioned were symptom control, psychosocial, and spiritual intervention. Conclusion: This study highlights the complexities of family involvement in palliative care and suggests the need for future research to develop more integrated and effective approaches to address the identified challenges.
Impacto do fluxo digital workflow em reconstruções de ameloblastoma na cirurgia bucomaxilofacial: revisão de literatura
Authors: Silva Alice Victória Oliveira da , Silva Felipe Ramon Gurgel da , Deip Luis Filipe Alves
Published: November 2024

O presente artigo aborda o uso de tecnologias digitais na reconstrução cirúrgica de ameloblastomas, tumores odontogênicos benignos, porém agressivos. A revisão de literatura foca na importância do fluxo de trabalho digital, que envolve o uso de ferramentas como CAD/CAM (projeto e manufatura assistidos por computador) e impressão 3D, tecnologias que aumentam a precisão e previsibilidade das cirurgias, especialmente em casos de ressecção mandibular. Observou-se a partir dos estudos revisados que o ameloblastoma, sendo uma lesão de crescimento lento e com alta taxa de recorrência, exige abordagens cirúrgicas variadas, que vão desde tratamentos conservadores até radicais, e o fluxo digital oferece benefícios, como a simulação prévia das etapas da cirurgia, o que melhora o planejamento e a execução dos procedimentos e o uso de guias cirúrgicas personalizadas também possibilita maior precisão na colocação de enxertos e próteses, resultando em melhor recuperação funcional e estética. Por outro lado, a revisão aponta desafios como o alto custo dessas tecnologias, que limita seu uso em algumas regiões. A adoção dessas ferramentas, no entanto, tem contribuído para a redução do tempo cirúrgico e de complicações pós-operatórias, melhorando a qualidade de vida dos pacientes. Conclui-se que o fluxo digital traz avanços significativos para as cirurgias reconstrutivas, mas sua acessibilidade precisa ser ampliada.
Mecanismos para manejo da dor pós operatória em endodontia
Authors: Souza Anny Graziele Reis de , Vazquez Ellen Regina de Lima , Corrêa Gaio dos Santos , Nunes Eduardo Costa , Fonseca Tiago Silva da
Published: November 2024

A dor pós-operatória é uma preocupação significativa em tratamentos endodônticos, afetando a qualidade de vida dos pacientes e a percepção dos resultados clínicos. A ocorrência e intensidade dessa dor variam de acordo com fatores como a resposta inflamatória local, o trauma mecânico durante o tratamento e a liberação de mediadores inflamatórios que sensibilizam as terminações nervosas. Estudos científicos têm explorado diferentes estratégias para o manejo dessa dor, incluindo abordagens farmacológicas e não farmacológicas. Este trabalho tem como objetivo geral investigar as evidências científicas existentes sobre os mecanismos e abordagens terapêuticas para a redução da dor pós-operatória em procedimentos endodônticos, a fim de fornecer uma visão abrangente sobre as melhores práticas e identificar lacunas para futuras pesquisas. A metodologia utilizada foi a Revisão Bibliográfica. Concluiu que o manejo da dor pós-operatória em endodontia requer uma abordagem abrangente, considerando tanto tratamentos farmacológicos quanto intervenções não farmacológicas, bem como fatores individuais do paciente. A revisão também destaca a necessidade de diretrizes baseadas em evidências para orientar a prática clínica e a importância de estudos futuros, especialmente sobre o impacto de condições sistêmicas, tratamentos alternativos e fatores genéticos. Esse trabalho contribui para aprimorar o atendimento odontológico, proporcionando um melhor manejo da dor e uma experiência de tratamento mais positiva para os pacientes.
Anestesia para cirurgia de hérnia inguinal laparoscópica: uma análise dos resultados pós-operatórios de diferentes técnicas
Authors: Queiroga Mariana Carvalho Silva de , Pereira Mayara Leite , Queiroga Demisson Carlos Botelho de , Gonçalves Elielson Felix , Sousa Júnior Adalberto Alves de , Ribeiro Filho Zades Lira , Muniz André Victor Teixeira , Almeida Luciana Gomes Vieira de , Melo Ghislayne Martins de , Carvalho Marina Medeiros Araújo , Almeida Bruna surlane Rodrigues de , Azevedo Milayne de Oliveira , Lira Ashlley Kessy De Sousa , Carvalho Ivna Naftali de , Santos Patrícia Silva dos
Published: November 2024

Introdução: A abordagem minimamente invasiva promoveu muitos avanços no tratamento da hérnia inguinal, no entanto a dor pós-operatória ainda é um fenômeno comum nesse tipo de procedimento e, se não tratada adequadamente, pode afetar negativamente a qualidade de vida e a recuperação do paciente. Objetivo: Sistematizar as informações referentes as diferentes técnicas anestésicas utilizadas na cirurgia laparoscópica de hérnia inguinal. Metodologia: Foi realizada uma revisão integrativa da literatura, incluindo ensaios clínicos randomizados, revisões sistemáticas e meta-análises publicados nos últimos 10 anos. A busca foi realizada na PubMed e BVS, a partir dos descritores DeCS: ‘‘Hernia, Inguinal’’, ‘‘Laparoscopy’’, ‘‘Anesthesia’’ e critérios de inclusão e exclusão previamente estabelecidos. Resultados e Discussão: A raquianestesia foi associada a menor dor no pós-operatório imediato e menor tempo para a recuperação funcional, no entanto a maior taxa de retenção urinária, hipotensão, cefaleia, morbidades perioperatórias gerais. Além disso, a adoção de abordagens como os bloqueios de nervos periféricos, revelou um papel significativo na redução da dor pós-operatória e no aprimoramento da qualidade de vida dos pacientes. Conclusão: Apesar da raquianestesia promover um benefício na redução da dor no pós-operatório imediato, a anestesia geral permanece como uma opção mais segura. Os bloqueios do TAP, psoas e quadrado lombar também podem melhorar a analgesia em cirurgias de hérnia laparoscópica.
Implante com uso de carga imediata – revisão de literatura
Authors: Vasconcelos Eduardo Araújo Marques de , Sena Eduarda Almeida de , Silva Isabele Laís Pinheiro da , Fonseca Tiago Silva da , Nunes Eduardo da Costa
Published: November 2024

O implante com o uso de carga imediata é uma técnica odontológica que permite a colocação de uma prótese dentária no mesmo dia da cirurgia de inserção do implante de titânio no osso. O propósito deste estudo foi explorar na literatura os implantes que utilizam carga imediata, discutindo a técnica e o tratamento, avaliando os critérios para suas indicações e contraindicações. O trabalho de revisão de literatura aqui apresentado teve como objetivo identificar os artigos mais significativos publicados entre 2004 e 2024. A abordagem do implante imediato, quando aplicada de maneira adequada, se revela uma opção de tratamento excepcional, uma vez que preserva o tecido ósseo e gengival. Dessa forma, a escolha de efetuar um implante com carga imediata deve ser fundamentada em uma análise minuciosa das particularidades de cada paciente.
Prevalência da obesidade e sua associação com fatores de risco
Authors: Cornatione Isabela Fernandes , Alvarenga Gabriela Sanches Vicente Carvalho de , Milanez Amanda Breseghello , Stella Mercia Breda
Published: November 2024

Introdução: A obesidade, uma inflamação crônica, está associada a doenças crônicas não transmissíveis (DCNT). Tem alto impacto socioeconômico e piora a qualidade de vida ao agravar outras DCNTs. Portanto, seu estudo é essencial para entender suas relações com outros fatores de risco. Objetivos: Investigar a prevalência da obesidade e fatores de risco como diabetes, risco cardiovascular e hipertensão em pacientes do Ambulatório da Faculdade de Medicina de Jundiaí. Métodos: Estudo de delineamento transversal, descritivo, de base populacional e contempla pacientes de 18 a 65 anos. Dados foram coletados manualmente de pacientes que assinaram o Termo de Consentimento Livre e Esclarecido (TCLE) e transpostos para o Excel e organizados em planilhas contendo as variáveis do estudo. Resultados: 80 participantes avaliados. A média do IMC foi de 28,5; 70,1% contêm alteração no IMC, 30% hipertensos, 28,7% dislipidêmicos e 17,5% diabéticos. As relações relevantes estabelecidas: 87% das mulheres e 75% dos homens com RCQ alterado apresentaram IMC alterado. Correlação hipertensão e IMC, 93,8% das mulheres hipertensas e 87,5% dos homens hipertensos apresentaram IMC alterado. A média RCQ acima do valor de referência indica risco moderado a alto para o desenvolvimento de doenças cardiovasculares. Fixando-se a significância estatística em 5% (alfa=0,05), por meio da tabulação cruzada entre IMC e diabetes e IMC e hipertensão obtém-se p<0.05, respectivamente, indicando dependência entre as variáveis. Já para a análise de IMC e dislipidemia e IMC e RCQ, tem-se p>0.05, em ambas, e desta forma não há relação de dependência entre as variáveis.
Análise dos resultados de nefrectomia parcial robótica e laparoscópica realizadas em hospital privado de Curitiba-PR
Authors: Meyer Fernando , Toppel Eduardo Zeve , Gomes Isabela Pontarolo
Published: November 2024

O câncer renal e de pelve renal são patologias malignas que apresentam significativa incidência na população atual, tendo seus prognósticos reservados e interligados a diversos fatores variáveis. Diante das alternativas de tratamento, encontram-se as cirurgias minimamente invasivas videolaparoscópica e conduzida por robô, as quais se mostraram eficientes e com boa resolução. O estudo apresentado a seguir teve como objetivo avaliar os resultados anatomopatológicos dos pacientes submetidos a nefrectomia parcial robótica e videolaparoscópica, buscando analisar o laudo histológico e definir benignidade ou malignidade da lesão, bem como a presença ou não de margens positivas, procedendo-se a avaliação histológica ao se analisar os resultados laboratoriais do material coletado no procedimento cirúrgico. Além disso, realizou a análise de parâmetros perioperatórios (tempos cirúrgico e de isquemia, além de sangramentos) e pós-operatórios (complicações e tempo de internamento) entre as técnicas em questão. Enquadraram-se no estudo 30 pacientes de hospital privado de Curitiba-PR operados pela mesma equipe cirúrgica durante março de 2021 e julho de 2023. A diminuição dos parâmetros supracitados é o desfecho primário. Desse modo, observa-se que média de duração da cirurgia foi menor nos pacientes submetidos pela técnica robótica em relação aos pacientes submetidos pela técnica videolaparoscópica, bem como o tempo de isquemia. O tempo de internamento foi menor nos pacientes operados pela técnica videolaparoscópica (p 0,049) – houve complicação em um (1) paciente submetido a NPRA, ocasionando maior tempo de internamento; após nova análise excedendo este caso, o valor de p não se mostrou significativo, indo de acordo com as referências utilizadas como base teórica do projeto (p 0,067). Com relação à malignidade e benignidade das lesões, nove (9) pacientes tiveram lesões com histologia benigna, representando 30% do total – sendo as lesões benignas mais prevalentes o oncocitoma renal e o cisto renal; o 70% restante enquadraram-se em lesões malignas. Demonstrou-se pelo estudo prevalência do tipo histológico, através da imuno-histoquímica, carcinoma de células renais tipo células claras como sendo a lesão mais incidente dentre os resultados histológicos com 42,9% (n = 13 pacientes). Acerca das margens cirúrgicas, apenas um (1) dos oito (8) pacientes submetidos à técnica videolaparoscópica apresentou margem positiva para a lesão; bem como seis (6) dentre os vinte e dois (22) pacientes abordados pela NPRA demonstraram margens positivas no pós-operatório. Em relação a comparação das técnicas robótica e videolaparoscópica, apenas uma variável obteve relevância estatística, sendo esta a idade (p = 0,016). A nefrectomia parcial robô-assistida se mostra inovadora, com resultados semelhantes a técnica aberta quando se analisa a presença de margens positivas da ressecção cirúrgica, confirmando estudos e revisões literárias neste tema.
Telemonitoramento na Doença de Parkinson: uma análise abrangente das implicações para a motricidade orofacial e intervenções fonoaudiológicas em idosos
Authors: Barbosa Erika Regina Maia , Lourenço Ílary Maria Mendonça , Santos Kelly Francielly Vilela dos , Godoi Naira Rúbia Rodrigues
Published: November 2024

A Doença de Parkinson (DP) é uma condição neurológica crônica e progressiva que afeta o sistema nervoso central, manifestada por sintomas motores e não motores, e redução das habilidades cognitivas em tarefas complexas. Com o avanço tecnológico, o telemonitoramento por tecnologias de informação e comunicação (TICs), como sensores vestíveis e aplicativos móveis, surge como uma ferramenta promissora na fonoaudiologia para monitorar biomarcadores motores e orofaciais. Objetivamos fornecer à comunidade científica uma compreensão abrangente das implicações do telemonitoramento para a motricidade orofacial e intervenções fonoaudiológicas em idosos com DP. Procedeu-se à revisão integrativa nas bases LILACS, PUBMED, SCIELO, NDLTD, Cochrane Library e CAPES. Empregados descritores “Doença de Parkinson”, “Atividade Motora” e “Fonoaudiologia”. Revisão por pares. As implicações em idosos com DP indicam que a integração de TICs de telemonitoramento possibilita uma avaliação contínua e precisa das alterações faciais e vocais. Esse telemonitoramento permite acompanhar sintomas como hipomimia e distúrbios na articulação e prosódia, viabilizando uma intervenção eficaz e ajustada às flutuações motoras características da doença. O uso de biomarcadores digitais para identificar padrões faciais e vocais facilitam o diagnóstico e acompanhamento da reabilitação, enquanto minimiza a sobrecarga dos cuidadores. Desafios como a representatividade dos dados e a capacitação de profissionais destacam-se como benefícios na rotina clínica. Limitado para monitorar múltiplos sintomas simultaneamente para garantir qualidade na coleta. Conclui-se que há contribuição para uma intervenção fonoaudiológica precisa em idosos com DP, especialmente na detecção de alterações orofaciais. Mais pesquisas são necessárias para comprovar sua eficácia e melhorar a aplicação prática no tratamento.
Evolução da mortalidade por doenças cerebrovasculares no Brasil: uma análise temporal e regional com dados do datasus (2000-2023)
Authors: Ribeiro Steve Biko Menezes Hora Alves , Barros Rafaela Santos de , Gomes Luara Bela Rocha , Leal Neto Hugo de Sousa
Published: November 2024

Introdução: As doenças cerebrovasculares, especialmente o acidente vascular cerebral (AVC), são uma das principais causas de morte no Brasil, causando grande impacto na saúde pública devido à sua alta taxa de mortalidade e morbidade. A mortalidade por AVC é influenciada por fatores regionais, socioeconômicos e de acesso aos serviços de saúde. Objetivo: Este estudo visa investigar a evolução da mortalidade por doenças cerebrovasculares no Brasil entre 2000 e 2023, analisando as disparidades regionais e o impacto de determinantes sociais e do sistema de saúde no comportamento das taxas de óbito. Metodologia: Realizou-se uma análise ecológica observacional utilizando dados do Sistema de Informações de Mortalidade (SIM) do DATASUS, com cálculo de taxas de mortalidade ajustadas por idade para as cinco regiões geográficas do Brasil. Foram aplicadas análises de regressão para avaliar associações entre mortalidade, Índice de Desenvolvimento Humano (IDH) e cobertura da Estratégia Saúde da Família (ESF). Resultados: Houve um declínio geral nas taxas de mortalidade por doenças cerebrovasculares em todas as regiões, sendo mais acentuado no Sul e Sudeste, onde o acesso a serviços de saúde e políticas de prevenção é mais robusto. No entanto, as regiões Norte e Nordeste continuam a apresentar taxas mais elevadas, evidenciando disparidades regionais significativas. Observou-se também uma relação inversa entre IDH e mortalidade, indicando que regiões com melhores indicadores socioeconômicos apresentam menores taxas de óbito. Conclusão: As políticas de saúde, incluindo a ampliação da ESF, têm contribuído para a redução da mortalidade por doenças cerebrovasculares no Brasil. No entanto, persistem desigualdades regionais que exigem estratégias específicas para as áreas mais vulneráveis, visando fortalecer a infraestrutura de saúde e ampliar o acesso a cuidados preventivos. Essa abordagem é essencial para uma redução mais equitativa das taxas de mortalidade em todo o território nacional.
Alterações e aspectos bucais relacionados a pacientes esquizofrênicos: revisão de literatura
Authors: Costa Samilly Rocha , Ferreira Ayra Yasmin Martins , Queiroz Ana Gabriela Oliveira , Varejão Livia Coutinho , Lima Thiago Mendes de
Published: November 2024

Os indivíduos acometidos por doenças psiquiátricas, como a esquizofrenia, apresentam estado de saúde oral crítico. O objetivo deste trabalho é realizar uma revisão de literatura sobre alterações bucais e dificuldades encontradas em sessões de atendimento odontológico em pacientes portadores de esquizofrenia. Consultou-se nos bancos de dados Pubmed e Scielo artigos publicados entre 2018 e 2024, utilizando palavras-chave: odontologia integrativa; esquizofrenia, assistência odontológica para a pessoa com deficiência. A educação em saúde é considerada de baixa prioridade ou limitada, entretanto, pacientes que recebem estímulos para obterem independência em realização de atividades do dia a dia foram positivas; esforços de coordenações médicas, odontológicas e assistência social são de grande importância para redução de discriminação. Drogas antipsicóticas são tratamento de escolha; observa-se reações adversas sistêmicas como ganho de peso e alterações cardíacas; oralmente, observa-se xerostomia e protrusão lingual, devendo ser monitorada e gerenciada. Conclui-se que a viabilização da assistência em saúde mental e bucal com o trabalho interdisciplinar promovem melhorias de qualidade e expectativa de vida de indivíduos esquizofrênicos.
Efektivitas Penerapan Strategi Pembelajaran Ekspositori dalam Meningkatkan Kualitas Hafalan Al-Qur’an Siswa di Sekolah Dasar
Authors: Delfianti Yesi , Asril Zainal , Zalnur Muhammad
Published: November 2024

This study aims to describe in depth the planning, implementation, supporting and inhibiting factors, and evaluation of the application of expository learning strategies in improving the quality of students' memorization of the Qur'an at Adzkia 1 Padang Integrated Islamic Elementary School. This research uses qualitative methods through a descriptive approach, the type of research used is field research. The results showed that Adzkia 1 Padang Integrated Islamic Elementary School has designed the implementation of learning in stages, starting from preparation, opening activities, core activities (including murajaah together and memorization deposits), to closing activities. Some of the supporting factors for the successful implementation of expository strategies include a conducive learning environment, grouping students based on ability, and choosing strategies that are considered easier for teachers and students. However, there are also some inhibiting factors such as boredom in learning, lack of independent murajaah, and lack of cooperation with parents. Thus, learning evaluation is carried out regularly through mutabaah books, weekly evaluations, and comprehensive exams. The evaluation results show an increase in the quality of memorization of the Qur'an in most students.