bluuebunny/crossref_metadata_2025 huggingface dataset:
Metaphors and weapons of war : a conceptual metaphor analysis of police use of war metaphors and militarized equipment
Authors:   , Jimenez Tyler
Published: December 2021

The 'War on Drugs' exemplifies one way in which policing is metaphorically compared to war. As conceptual metaphor theory demonstrates, metaphors shape attitudes and behaviors toward the concept they are used to understand. It is then perhaps unsurprising that war metaphors for policing have become more common alongside the militarization of police. Still, no research has examined the link between police use of war metaphors and acquisition of military equipment. Using ecological and social media data, the study began to examine this link. Specifically, 241,084 social media posts from police departments (N = 80) were coded for the presence of war metaphors, which were then used to predict the amount of military equipment acquired through the federal 1033 Program. Building from conceptual metaphor theory, it was hypothesized that police use of war metaphors would be positively associated with their department acquisition of militarized equipment. The results did not support this hypothesis; potential reasons for this are considered. Exploratory analysis generated potentially interesting findings regarding police usage of war metaphors following acts of police violence and associations between death-related words and militarized equipment acquisitions.
Barriers and catalysts of aging for LGBTQ+ older adults : a photovoice study
Authors:   , Kerr Steffany
Published: December 2021

For LGBTQ+ older adults, the intersecting influence of sexuality, gender expression, and sociocultural factors result in a distinct aging experience. The concept of successful aging is often utilized by professionals to guide policy and practice for aging populations, yet LGBTQ+ older adults are frequently absent from dominant perspectives on aging. To examine barriers and catalysts for successful aging from a queer perspective, Photovoice--a visual participatory research method--was utilized to engage participants (n = 9) in visually and verbally expressing their lived experience about barriers and catalysts of successful aging and overall aging experiences. The Photovoice exhibit was utilized as an educational tool for key stakeholders including health, legal, social welfare, and business professionals (n = 38). After viewing the virtual exhibit, stakeholders completed an online survey about the potential impact of the exhibit and reactions to the content. DBTQ+ Photovoice participants, two primary themes were identified pertaining to what it means to age successfully as an LGBTQ+ individual: The Relational Landscape and Re-Writing the Narrative. Themes highlighted the centrality of the relationship with oneself, queer identity, and one's support network. Further, these themes articulated the importance of advocacy and representation as salient to feeling successful in later life. The key stakeholder survey yielded two themes pertaining to the educational impact of the Photovoice exhibit: Images Brought Stories to Light and Nature of Identity. These themes illustrated the ways in which professionals connected emotionally to the stories and images, and their learning about the importance of identity and timing of coming out for LGBTQ+ individuals.
Social justice leadership in rural Pakistan : a constructivist grounded theory study of private school leaders
Authors:   , Marwat Palwasha Khan
Published: December 2021

This qualitative constructivist-grounded theory (C-GT) study aimed to explore how Pakistani school leaders (PSL) conceptualize and enact social-justice-oriented leadership (if they do) to combat educational and sociocultural inequities to support marginalized students. This study collected data from 11 rural school leaders, over 11 primary and secondary private schools that educate marginalized students, including low-income families, girls, and minority groups in rural areas surrounding Islamabad. Utilizing social justice leadership (SJL) and mental models (MM) as a conceptual framework, I undertook an in-depth, semi-structured interview protocol with each school leader in addition to artifact collection, analytical memos, and diagrams. The emerging grounded theory is a five-step model identifying participants' MM of SJL and exploring their views and actions to address the educational inequities for marginalized students. The findings suggest that school leaders conceptualized and emarginalized students' access to high-quality education that was context-appropriate and encouraged critical awareness. However, most PSL had not received formal training in school leadership and shared some conflicting and problematic MM of leadership as adult-centered, hierarchical, and savior-like. This finding diverges from existing literature on SJL, which is democratic, inclusive, and empowering all stakeholders. Based on the results of this study, MM was a useful lens to explore PSLs' views of justice and equity and how they subsequently enacted social justice to address inequities prevalent in their schools and communities to support marginalized students. Keywords: social justice leadership, mental models, rural schools, marginzalized students
Supporting disaster impacted youth : evaluation of a universally delivered online mindfulness intervention
Authors:   , Mills Toby M.
Published: December 2021

There is an increase in youth-reported traumatic stress, youth behavioral health problems, and an upward trend in the prevalence and severity of large-scale disasters within the US. Youth are especially vulnerable to adverse behavioral health problems following a disaster. Many young people do not seek treatment for their behavioral health problems and this discrepancy is magnified by various obstacles to successfully implementing school-based behavioral health interventions to youth impacted by disasters. Youth experiencing internalizing symptoms and youth of color are disproportionately impacted by disaster-related stress and are less likely to receive behavioral health interventions after a disaster. As such, researching the impact of universally delivered programs for this population is warranted. The current study seeks to examine the feasibility and initial efficacy of an online adaptation of the Dynamic Mindfulness program in a quasi-experimental, within-group/ pretest-posttest design, with 44 youth, ages 11-17. The evidence demonstrates that the online adaptation of the selected youth mindfulness program was feasible, acceptable, and related to significant, short-term, pretest to posttest improvements in several of the targeted outcomes and reveals a significant relationship between youth-reported mindfulness and various social and emotional outcomes within study participants, warranting continued inquiry within this scope of research.
Historical rainfall analysis and climate implications for agriculture in midwest United States
Authors:   , Niemeyer Jane Marie
Published: December 2021

A historical analysis of precipitation using 72 years of data from Midwest stations focuses on the implications of climate change for agricultural interests. The number of precipitation events, consecutive days of precipitation, and a Fourier transformation on precipitation are included. Although increased precipitation can be of benefit in agricultural production resulting in yield benefits in the Midwest, excessive rainfall events lead to runoff, which does not improve soil water content and plant available water. To examine the beneficial nature of rainfall events in the Midwest, rainfall retention is estimated using the United States Department of Agriculture Soil Conservation Service (USDA-NRCS/SCS) method. This method can be described briefly as an empirical formula estimating the soil's ability to store water and the amount of runoff. It was found that not only has rainfall increased but so have the number of rainfall days and the number of consecutive days of rainfall. To appricultural focus, spring and fall rainfall days were also found to increase implying that farmers may have fewer days to complete fieldwork in the current climate. With increasing precipitation, the potential for runoff also increases, losing valuable water needed for crops and contributing to lost nutrients in the soil.
Does geography matter? comparing maternal stressors to birth outcomes
Authors:   , Reed Amy E.
Published: December 2021

Background: The US continues to see rising trends in the incidence of maternal morbidity and mortality, which contributes to poor infant birth outcomes of preterm birth and low birth weight. The purpose of this dissertation study was to examine the relationship between the experience of stress and birth outcomes of weight and gestational age based on whether the mother resided in a rural or urban location in the state of Missouri. Methods: A secondary data analysis was conducted using the Missouri Department of Health and Senior Services PRAMS survey between 2007-2019. There were 15,938 respondents -- 11,475 urban and 4,463 rural. Stress measures included responses from 13 items on the PRAMS survey related to the experience of stress within the 12 months before delivery of their infant. A mean stress score for each participant was created, which was an average of the 13 stressors experienced. The 13 stressors were also grouped into four different domains: Community, Family/Relationshipd Health. Participant responses are tied to birth certificate data to obtain outcome variables related to infant birth weight (<2500 grams) and gestational age (<37 weeks) at time of delivery. Univariate and multivariate models were analyzed for the total sample and also for urban and rural participants with and without covariates. Results: Rural childbearing women were younger, less likely to have received prenatal care during the first trimester and more likely to have smoked cigarettes than urban childbearing women. Urban women were more likely to have education beyond high school, and more likely to use alcohol during pregnancy. Similar to other research, Black women were more likely to experience PTB or have a LBW infant than other race/ethnicities. The number of stressors reported by both urban and rural women is similar, with rural women reporting slightly more. The experience of stress is significant for both urban and rural women, even when controlling for covariates. Stress scores significantly predicted low birth weight and preterm birth for urban participants. The four different categories of grouped stress scores were not significant for either urban or rural participants and did not significantly predict low birth weight or preterm birth. Conclusion: Health care providers should screen women for stressors related to the social determinants of health in order to provide opportunities for support and intervention. Policies that ensure access to convenient, appropriate obstetric resources for pregnant women, regardless of location could improve outcomes. Research that seeks to understand differences in health between rural and urban populations should consider additional measures related to urban and rural classification of participants.
Découverte d’une nouvelle population de Rhithrogena delphinensis Sowa & Degrange, 1987, dans le massif des Arves, et compléments à la description de la larve (Ephemeroptera, Heptageniidae)
Authors: Launay Bertrand , Barnasson Julien , Becquet Juliette , Brulin Michel , Cauvy-Fraunie Sophie , Forcellini Maxence
Published: December 2021

Discovery of a new population of Rhithrogena delphinensis Sowa & Degrange, 1987, in the Arves Massif, and additions to the morphological description of the larva (Ephemeroptera, Heptageniidae). Rhithrogena delphinensis, described originally on the basis of four larvae from the Western Alps, south of the Arves Massif and from the northern flank of the Ecrins Massif, had not been captured again since 1986. Here, we report the discovery of a new population from river Arvan, whose drainage basin is located between the Grandes Rousses Massif and the northern flank of the Arves Massif. This newly discovered population seems abundant in numbers, and reveals the particular ecological requirements of the species as well as its dependence on glacier fed or nival streams. The morphological characteristics of the larvae are described in detail, and illustrated by photographs. The variability of some of the proposed identification criteria is discussed, and a key to the identification of the Rhithrogena species from the alpestris group of the Western Alps, to which R. delphinensis belongs, is provided. Finally, a portion of 658 base pairs of the COI gene of R. delphinensis is sequenced for the first time and compared to already existing data on the alpestris group in the Western Alps.
Characterizing the taxonomic status of Sphingonotus caerulans in the upper Rhine Valley of Alsace (France) (Orthoptera, Acrididae, Oedipodinae)
Authors: Vacher Jean-Pierre , D'Agostino Roberto , Ursenbacher Sylvain
Published: December 2021

Sphingonotus is a genus of grasshoppers that contains species groups with several closely related species, among which Sphingonotus caerulans and an unnamed Sphingonotus that are found in continental France. The exact distribution of both species is still under investigation, but it is believed that S. caerulans might be restricted to the northern part of the country, and that Sphingonotus sp. occurs in the southern half and might reach the north east. We explored the genetic identity of Sphingonotus grasshoppers in the upper Rhine Valley of Alsace (northeastern France) using combined fragments of mtDNA ND5 and cytb genes included with other available samples in ML and Bayesian phylogenetic analyses. The results indicate that the five specimens sampled within this region belong to S. caerulans. The actual distribution of Sphingonotus sp. in France remains to be investigated with wider sampling, especially to get a better knowledge on its northern limit.
Debate in informatics lessons using the Kialo Edu resource
Authors: Sheveleva E. Yu.
Published: December 2021

The article discusses the need for the formation of communicative competence in students at the level of basic general education. It is proposed to use the "Debate" technology as a means of forming communicative competence. The stages and organizational features of the classic Karl Popper debates are described, the main difculties associated with their conduct in the classroom are highlighted. A list of possible topics for organizing debates in informatics lessons is given. A description of the Kialo Edu resource that facilitates debate is given. The resource toolkit is demonstrated in detail. The examples show how you can use the resource to accompany the debate on one or more theses, how to create counterarguments and leave comments on the added statements. An example of organizing a debate in 9th grade on the topic "Internet communication as a worthy substitute for real contacts" within the framework of the study of the theme "Communication technologies" using Kialo Edu is given.
Using digital tasks when teaching mathematics at school
Authors: Lebedeva N. A. , Chernetskaya T. A.
Published: December 2021

The article discusses various types of digital math tasks to be performed on computers or tablets. The experience of creating digital tasks in mathematics with complex answers from the point of view of automatic verifcation: algebraic expressions, geometric constructions, graphs of functions, etc. is discussed. As an example of the use of digital tasks, the use of digital materials for preparing schoolchildren for the Unifed State Exam in mathematics of a profle level is considered. The article also discusses various forms of using simulators and tests in the educational process: supporting the independent activities of students in the full-time educational process, supporting online learning with a teacher in the context of the coronavirus pandemic, independent online learning without a teacher based on specially prepared and structured training courses. In the latter case, in addition to simulators, it is proposed to use other digital educational resources to increase the visibility of the educational material and organize self-control of learning outcomes: videos, slides, dynamic models, training exercises for problems with a detailed answer to the options for the USE control and measuring materials.
Prescription Profile of Antibiotic Drugs Post Excision Biopsy of Oral Soft Tissue Disease in Palembang
Authors: Nadhila Apriadhanti  , Parisa Nita , Siti Rusdiana Puspa Dewi
Published: December 2021

A B S T R A C TBackgroud An excisional biopsy is one of the surgical treatments given to cases ofsmall benign tumors in the soft tissues of the oral cavity. Antibiotics are prescribedby dentists as a follow-up therapy after excisional biopsy to prevent bacterialinfection. The purpose of this study was to determine the profile of antibiotic drugprescription after excision biopsy of oral soft tissue disease by dentists in Palembang.Methods This type of research is descriptive observational with a survey method.The research was carried out by distributing questionnaires to 40 dentists anddental specialists in Palembang who had performed excision biopsy treatment fororal soft tissue disease. Result The results showed that the antibiotic prescriptionof amoxicillin was 55%, the combination of amoxicillin and clavulanic acid was17.5%, and clindamycin was 12.5%. The cases found in this study were epulis57.5%, mucocele 30%, and traumatic fibroma 10%. Conclusion It can be concludedthat the antibiotic most often prescribed by dentists in Palembang after excisionbiopsy treatment was amoxicillin and the most common case was epulis.
The Influence of Knowledge, Attitudes and Behavior of Cleaning Officers with the Number of Mosquito Larvae in the Water Reservoir Punti Kayu Palembang City
Authors: Aldi Alfian  , Anwar Chairil , Iche Andriyani Liberty
Published: December 2021

A B S T R A C TBackground Mosquito was one of the animals that can transmit deadly diseases.Information about water reservoirs as their habitat as well as human knowledge,attitudes and behavior factors are considered important to help eradicate mosquito.This study aims to determine the effect of knowledge, attitudes and behavior ofcleaners on the number of mosquito larvae in water reservoirs in Palembang.Methods This research was mixed method research (quantitative and qualitative) inthe field and laboratory. The research samples were all mosquito larvae andcontainers found. The research respondents were all cleaning services. Data werecollected by interviewing and filling in questionnaires, observing water reservoirsand identifying the types of mosquito larvae in microscope. Results A total of 40containers were found in Punti Kayu Nature Park. There were 8 containers that wereindoors (20%) and 32 containers were outdoors (80%) with 17 containers containedlarvae. Of all the containers that were positive for larvae, 6 were filled with clearwater and 11 were filled with turbid water. The number of larvae found were 358larvae outdoors and 82 larvae indoor with a total of 440 mosquito larvae with thegenus Culex spp. and Aedes albopictus species. The index of mosquito larvae wereobtained FLI (Free Larva index)=66,67%, HI (House Index)=33,33%, CI (ContainerIndex)=16,67%, BI (Breteau Index)=33.33% from the 3 buildings examined. Fromthese results, it was obtained DF (density figure) or density level of 5. There were 40containers that could be habitats for Culex spp. and Aedes albopictus. ConclusionThe knowledge, attitude and behavior of the cleaning services were good. Thenumber of mosquito larvae could be influenced by the frequency of cleaning and thelack of knowledge of the cleaning services.
The Association between Aromatase Gene Polymorphism Cyp19 Val 80 and Endometriosis Risk
Authors: Alkaf Syifa , Ziske Maritska  , Venny Patricia
Published: December 2021

Background: Endometriosis implant has been known to express aromatase enzyme, Cytochrome p450 that catalyzes androgen into estrogen. It causes local estrogen production, leading to increased estrogen level, and subsequently triggers endometriosis lesion. CYP19 gene resided at chromosome 15q21.1 is the biggest component of aromatase coding cytochrome p450 enzyme.

Objective: To identify relationship between aromatase gene polymorphism CYP19 Val 80 and the risk of endometriosis. Methods: This is an observational case-control study using frozen DNA sample from women with endometriosis and/ or adenomyosis who had undergone laparotomy/ laparoscopy at Obstetrics and Gynecology Department Dr. Mohammad Hoesin General Hospital Palembang January-November 2013. Samples were amplified and cut by PCR-FRLP using Rsa1 restriction enzyme. Results were divided into A/A genotype (homozygote mutant), G/A (heterozygote mutant), and G/G (homozygote wild type).  Data were analyzed by SPSS 21.0 version.

Results: PCR-RFLP results for A/A genotype were 20 (21.3%) in endometriosis group and 8 (8.5%) in control group. G/A genotype were 18 (19.1%) in endometriosis group and 22 (23.4%) in control group. G/G genotype were 9 (9.6%) and 17 (18.1%) in endometriosis group and control group, respectively. There was significant increase risk of endometriosis in women carrying genotype A/A to those with genotype G/G with OR 4.722 (p<0.05).

Conclusion: Polymorphism on aromatase gene CYP19 Val 80 A/A increases risk of endometriosis.
Klippel Trenaunay Syndrome: A Brief Overview
Authors: Permatananda Pande Ayu Naya Kasih , I Gusti Agung Made Adnyana Putra
Published: December 2021

Klippel-Trenaunay syndrome is a rare congenital vascular disease. The pathogenesis of this syndrome is unclear, but it is thought that most cases are the result of somatic mutations that affect genes that play a role in vasculogenesis and angiogenesis. Some patients come with a triad of capillary malformation (hemangioma or port-wine stain), venous varicosities and bony or soft tissue hypertrophy. Clinical presentation of this syndrome can lead to significant morbidities and mortalities due to severe bleeding and emboli. Although the number of cases is low, a doctor must be able to distinguish Klippel-Trenaunay Syndrome from other rare vascular disorders. Parkes Weber syndrome is usually similar to Klippel-Trenaunay syndrome, except in the arterial malformations associated with capillary malformations and soft tissue to skeletal or bone hypertrophy. The diagnosis of Klippel-Trenaunay Syndrome is carried out clinically and is quite difficult to do even with experienced doctors because there is no precise pathognomonic test.  There are several options in relation to the management of Klippel-Trenaunay Syndrome and non-invasive procedure is considered to be the most important of therapy modalities. Early diagnoses, progression monitoring, and proper intervention should be carried out for better prognosis and preventing complication.
Anemia in Chronic Kidney Disease : Role of Hypoxia Inducible Factor Stabilizer
Authors: Emilia  , Zulkhair Ali
Published: December 2021

Anemia contributes to increased morbidity and mortality in chronic kidney disease patients. The pathogenesis of anemia in these patients is multifactorial, but the contribution of erythropoietin deficiency becomes greater as glomerular filtration rate declines which related to decreased nephron mass. The current standard of care includes supplemental iron, erythropoiesis-stimulating agents (ESA), and red blood cell transfusions, although each has drawbacks. Lately, concern has arisen following randomized clinical trials showing that higher hemoglobin targets and/or high ESA doses may cause significant harm including increasing cardiovascular and thrombotic events, and even death. Recent experimental and clinical studies show the promising efficacy of hypoxia inducible factor (HIF) stabilizer which stimulates endogenous erythropoietin production and enhance iron availability.
Staphylococcal Scalded Skin Syndrome in Healthy Infant
Authors: Harmen Anggia Perdana , Eny Yantri
Published: December 2021

Staphylococcal scalded skin syndrome (SSSS) describes a spectrum of superficial blistering skin disorders caused by the exfoliative toxins of Staphylococcus aureus that originates from a focus of infection that may be a purulent conjunctivitis, otitis media, or occult nasopharyngeal infection. It usually begins with fever, irritability, and a generalized, paint, orange-red, macular erythema with cutaneous tenderness, and the rash progress from scarlatiniform to a blistering eruption in 24 to 48 hours. A diagnosis must distinguish SSSS from other skin diseases, such as toxic epidermal necrolysis, epidermolysis bullosa, bullous erythema multiforme, Streptococcal impetigo or listeriosis and thermal or chemical burns, all of which can manifest with similar symptoms. The prognosis of SSSS in children who are appropriately treated is good, with a mortality of less than 5%. A case was a three moths old boy hospitalized in Pediatric ward M. Djamil hospital with chief complain redness and peeling of the skin since 2 days before hospitalized. Culture of the skin, eyes and nose was Staphylococcus aureus, and patients was given ampicillin and gentamycin for seven days.
Etiology, Diagnosis, and Treatment of Leukorrhea
Authors: Trilisnawati Damai , Izazi Hari Purwoko  , Mutia Devi  , Suroso Adi Nugroho  , Fitriani  , Theresia L. Toruan
Published: December 2021

The most frequently reported complaints in the urogenital organ system is leukorrhea, also known as fluor albus. Leukorrhea is a discharge secreted from the genital organs, mostly occur in female. Leukorrhea has a significant incidence rate and varies according to many factors such as hormone and infection. Leukorrhea can be physiological in female, but when excess discharge is accompanied by other characteristics, the leukorrhea is considered pathological. This genital discharge also occurs in male for pathological reasons, mainly caused by infection. Several pathogenic infections, whether transmitted through secual contact or not, are the etiology of complaints of leukorrhea. Some specific pathogens will cause different symptoms in the two sex groups. To make a diagnosis, it is important for the examiner to carry out a detailed and coherent history, especially regarding sexual contact and a history of risky sexual behavior. Although some infections are asymptomatic, complications may occur if infections are not treated properly as early as possible. The management of leukorrhea is based on an examination and treatment algorithm with syndromic approach.
Cardiac Septal Defects in Children: Hemodynamics, Clinical Manifestations and Detection
Authors: Ria Nova  , Sukman Tulus Putra  , Siti Nurmaini  , Radiyati Umi Partan
Published: December 2021

Cardiac septal defect in children is one of the congenital heart defects characterized by atrial septal defects (ASD), ventricular septal defects (VSD) and defects in both atrial and ventricular septum (AVSD). The hemodynamic changes that occur are caused by a left to the right shunt. Differences in location, size of the defect and pulmonary vascular resistance make hemodynamic differences and clinical manifestations between the three types of cardiac septal defects. Detection of cardiac septal defects can be done by clinical examination by listening to the characteristic heart sounds and murmurs for each defect. However, clinical examination alone is often still difficult to determine the type of cardiac septal defect so that several supporting examinations such as photothorax, ECG, echocardiogram and cardiac catheterization need to be done to help establish the diagnosis.
Control of HIF-1α Levels Potentially Promotes the Tissue Repair in Various Conditions Through Target Gene Expression
Authors: Firdaus Riyadh , Prijanti Ani Retno
Published: December 2021

Hypoxia inducible factor-1 (HIF-1) is a transcription factor that plays an important role in maintaining oxygen balance at both the cellular and systemic levels, and is associated with various controls in the body. HIF-1 is a heterodimer of alpha and beta subunits. Alpha subunits are mostly dependent on oxygen levels in the body. In many cancers, excessive HIF-1α is thought to be involved in the promotion of tumor growth and metastasis. In addition, in the induction of systemic hypoxia, there is an increase of HIF-1α in the heart, brain, and even the kidneys as an adaptation response to hypoxia. Several studies regarding HIF-1a expression in traumatic brain injury, found that HIF-1a increased immediately after TBI, and decreased significantly after 24 hours. This can be used as a basis for further research on HIF-1a control as an effort to stop tissue damage or even help tissue repair.
Geografi Emosi Tentang COVID-19 pada Pelajar
Authors: Andriyani Septian , Rahmi Upik , Sulastri Afianti , Darmawan Dadang
Published: December 2021

Latar Belakang : Corona virus 2019 (COVID-19) merupakan salah satu jenis virus yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), telah muncul sebagai ancaman kesehatan global Indonesia menjadi salah satu negara yang terkena dampak dari pandemi COVID-19. Selama masa pandemi banyak orang menunjukkan respon yang terkait dengan stres atau kecemasan. Anak â€“anak dan remaja mengalami kecemasan, takut, merasa tertekan, merasa tidak tenang, dan khawatir sehingga dapat menyebabkan gangguan emosi. Adapun tujuan dari penelitian ini adalah untuk mengidentifikasi geografi emosi tentang COVID-19 pada siswa SMPN VIII di Kota Cimahi. Metode : Desain penelitian yang digunakan adalah deskriptif kuantitatif. Teknik pengumpulan data menggunakan google form yang disebar secara online kepada siswa. Alat pengumpulan data yang digunakan adalah mengacu kepada instrumen standar COVID Stress Scales (CSS) 2020 dengan 36 item pernyataan. Hasil : geografi emosi siswa paling tinggi berada pada domain Xenophobia dengan nilai rata-rata sebesar 3,394, selanjutnya adalah domain danger dengan nilai rata-rata 3,327. Untuk nilai rata rata yang paling rendah yaitu berada pada domain Compulsive Checking dengan nilai rata-rata 2,107. Selama pandemi nilai rata-rata geografi emosi tertinggi berada pada domain ketakutan (xenophobia). Kesimpulan : Xenophobia dalam ancaman penyebaran COVID-19 dapat meningkatkan ketakutan membawa penyakit sehingga mengarah pada penurunan kesejahteraan secara emosi. Pentingnya dapat meningkatkan kesejahteraan di masa pandemic COVID-19.
Gambaran Penggunaan Antibiotik pada Pasien Bedah Orthopedi di Rumah Sakit Pusat Infeksi Prof. Dr. Sulianti Saroso Januari-Juli 2019
Authors: Wulandani Epi , Mariana Nina , Hartono Teguh Sarry , Sugianto Muhammad Taufik , Wijaya Chandra , Chandra William , Hardiansyah Nico Perdana
Published: December 2021

Latar Belakang: Kejadian infeksi pada kasus bedah orthopedidapat mempengaruhi morbiditas dan mortalitas. Ketepatan penggunaan antibiotik baik profilaksis maupun empirik pada tindakan pembedahan sangat penting untuk mengurangi risiko Â resistensi bakteri dan Healthcare Associated Infections (HAIs) contohnya Infeksi Luka Operasi (ILO). Penelitian ini bertujuan untuk mengetahui gambaran penggunaan antibiotikÂ  sebagai profilaksis dan empirik pada pasien bedah orthopedi. Metode: Penelitian observational deskriptif dengan desain cross sectional terhadap data rekam medis pasien bedah orthopedi RSPI Prof.Dr. Sulianti Saroso periode Januari-Juli 2019 yang diambil dengan teknik total sampling dengan pendekatan retrospektif. Hasil: Diperoleh 52 rekam medis yang memenuhi kriteria inklusi dengan 84 peresepan antibiotik. Pasien perempuan sebanyak 55,77% sedangkan laki-laki 44,23% ; jenis operasi bersih 71%, kotor 17% dan bersih-terkontaminasi 12%; pasien tanpa penyakit penyerta sebanyak 55,77%, satu penyakit penyerta 32,70% dan â‰¥ 2 penyakit penyerta 11,53%. Penggunaan antibiotik terapi empirik 72,62% dan profilaksis 27,38%. Antibiotik empirik dan profilaksis yang paling banyak digunakan adalah ampicillin sulbactam (42,65% dan 52,17%). Jenis kasus ortopedi terbanyak adalah kasus infeksi sebanyak 53 %. Kesimpulan: Penggunaan antibiotik empirik maupun profilksis bedah terbanyak pada pasien bedah orthopedi di RSPI Prof. Dr. Sulianti Saroso adalah ampicillin/sulbactam.
Aplikasi Smartphone Efektif digunakan untuk Pengawasan Keseimbangan Cairan pada Anak dengan Penyakit Infeksi
Authors: Nuraidah Nuraidah , Nurhaeni Nani , Wanda Dessie
Published: December 2021

Latar belakang: Keseimbangan cairan sangat penting untuk kelangsungan hidupÂ  sehingga pengawasan cairan perlu diperhatikan. Pencatatan keseimbangan cairan diperlukan untuk menjadi dasar penilaian yang akurat dari status keseimbangan cairan pasien anak dan menjadi dasar pertimbangan pemberian terapi selanjutnya. Untuk memudahkan perawat melakukan pencatatan keseimbangan cairan yang akurat diperlukan inovasi menggunakan teknologi berbasis smartphone. Penelitian ini bertujuan untuk mengetahui perbedaan efektifitas pengawasan cairan menggunakan lembar observasi dengan aplikasi smartphone. Metode: Penelitian ini diawali dengan pengembangan aplikasi smartphone bernama SIMBaCaAn berdasarkan tinjauan pustaka yang dilakukan menggunakan pendekatan PICO (Population, Intervention, Comparison,Outcome). Uji efektifitas aplikasi SIMBaCaAn dilakukan pada 48 pasien anak yang dirawat di salah satu rumah sakit rujukan di DKI Jakarta. Analisis data dilakukan menggunakan uji statistik Kappa Test. Hasil: Pengawasan keseimbangan cairan yang menggunakan lembar observasi menghasilkan pencatatan data tidak lengkap sebesar 14,6%, data lengkap tidak tepat 20,8% dan data lengkap tepat sebanyak 64,4 %. Sedangkan pengawasan keseimbangan cairan menggunakan aplikasi SIMBaCaAn didapatkan hasil data tidak lengkap 18,7% dan hasil data lengkap tepat 81,3%. Dari hasil uji statistik, ditemukan perbedaan yang signifikan antara pengawasan keseimbangan cairan menggunakan aplikasi dan lembar observasi. Kesimpulan: Aplikasi smartphone lebih efektif terhadap pencatatan keseimbangan cairan secara lengkap tepat dibandingkan dengan lembar observasi manual.
Kompres dengan Teknik Warm Water Sponge pada Pasien Anak yang Mengalami Demam
Authors: Agustina Novita , Nurhaeni Nani , Wanda Dessie
Published: December 2021

Latar belakang: Demam pada anakÂ  menyebabkan orangtua membawa anaknya ke pelayanan kesehatan dan menjadi penyebab utama anak dirawat di rumah sakit. Warm water sponge adalah satu mekanisme menurunkan demam pada anak dimana keberhasilannya bisa mencapai 100 %, namun penggunaannya di Indonesia baru sebatas kompres dengan teknik tepid water sponge. Oleh karena itu tujuan dari study ini adalah untuk melihat efektifitas kompres menggunakan teknik warm water sponge pada anak dengan peningkatan suhu tubuh. Metode: Desain yang digunakan adalah quasi eksperimental pre-posttest with control group design. Responden berjumlah 36 pasien anak yang mengalami demam yang dipilih menggunakan teknik consecutive sampling, terdiri dari 18 pasien anak menerima perlakuan warm water sponge dan 18 pasien anak menerima perlakuan kompres sesuai standar rumah sakit. Analisis yang dilakukan adalah uji T Independent. Hasil: Intervensi warm water sponge efektif menurunkan suhu tubuh anak yang mengalami demam dengan hasil uji T Dependent diperoleh Â Pvalue =0,000 < Î± (0,05). Kesimpulan: Warm water sponge efektif menurunkan suhu tubuh pasien anak yang demam dan pasien anak lebih merasa nyaman dibandingkan dengan terapi penurunan panas yang biasa dilakukan di rumah sakit.
Intertekstualitas Hukuman Bagi LGBT dalam Al Qur`an dan Hadis Perspektif Semiotika Julia Kristeva
Authors: Sifa Layyinatus
Published: December 2021

Beberapa waktu terakhir ini, kita dihadapkan dengan berbagai isu yang hangat menjadi perbincangan dalam masyarakat. Salah satunya isu tentang LGBT (Lesbian, Gay, Biseksual dan Transgender). Kehadiran kelompok mereka dirasa semakin banyak dan menjamur tak bisa dibendung lagi. Fenomena ini sebenarnya bukanlah sesuatu yang baru, eksistensi mereka telah ada sejak ribuan tahun yang lalu. Sebagaimana dikisahkan dalam al Quran bagaimana perilaku seksual kaum Nabi Luth, bahkan pada zaman Nabi Muhammad SAW pun kelompok ini ada. Fakta ini dapat kita lacak dari berbagai hadis Nabi yang menyinggung tentang kelompok LGBT dalam istilah yang berbeda. Dari beberapa hadis dan ayat al Quran tersebut, ada satu hadis yang menyerukan kepada kita untuk membunuh seseorang yang berperilaku menyimpang tersebut. Dan hadis tersebut kini seolah menjadi senjata senjata untuk menyingkirkan eksistensi kelompok LGBT.
Kedudukan Saksi Ahli dalam Persidangan Perkara Pidana
Authors: Arini Khafifah Nuzia , Sujarwo Herman
Published: December 2021

Di dalam pedoman pelaksanaan Kitab Undang-Undang Hukum Acara Pidana (KUHAP) dijelaskan, bahwa tujuan hukum acara pidana untuk mencari dan mendapatkan kebenaran, setidaknya mendekati kebenaran materil. Artikel ini menjelaskan mengenai peran, posisi dan kualifikasi saksi ahli dalam persidangan perkara pidana. Saksi ahli adalah orang yang memiliki pengetahuan dan pengalaman yang khusus sebagai dasar dalam memberikan keterangan yang dapat digunakan sebagai alat bukti di sidang peradilan pidana agar keterangan yang diberikannya. Diharapkan dapat membuat terang suatu tindak pidana sehingga hakim bisa memberikan keputusan dengan seadil-adilnya. Saksi ahli dianggap sebagai salah satu alat bukti dalam persidangan pidana sebagaimana yang diatur dalam KUHAP. Keterangan ahli merupakan suatu kemajuan dalam perkara di persidangan, dan pembuat Undang-Undang menyadari pentingnya kolaborasi perkembangan ilmu pengetahuan dan tehnologi, sehingga keterangan ahli sangat memegang peranan dalan peradilan. Kedudukan saksi ahli dalam pembuktian tindak pidana merupakan bagian dari sebagai alat bukti yang sah dan diakui di dalam Pasal 184 Ayat 1 KUHAP. Kekuatan pembuktian keterangan ahli menurut Hukum Pidana memiliki dasar hukum di dalam KUHAP bahwa keterangan ahli bersifat bebas dan tidak mengikat (dikesampingkan). Karena adanya keterbatasan hakim yang berkaitan dengan ilmu pengetahuan, maka hakim dalam persidangan bisa menggunakan keterangan ahli tersebut atau dikesampingkan, sehingga hakim dapat memberikan keputusan yang seadil-adilnya.
Analisis Kebutuhan SDM di mulai dari Sejak Sekolah Kejuruan dalam rangka Pengembangan Karir di Dunia Usaha
Authors: Muhammad Maryani , Yuniarsih Niar , Marganus Eko , Rosihan Riviega
Published: December 2021

Penelitian ini bertujuan untuk mengetahui analisis kebutuhan sumber daya manusia dan perencanaan karir pada siswa sekolah kejuruan melalui upaya layanan bimbingan kelompok dengan teknik mind mapping terhadap perencanaan karir siswa
Assessment of Vietnamese nurse’s knowledge and practice regarding patient’s safety after coronary angiography or percutaneous coronary intervention
Authors: Nguyen Nghia Thuong , Le Diem Thi Phuc
Published: December 2021

Many clinical and paraclinical studies related to coronary artery disease have been done in Vietnam in recent years. However, there have been no studies on nurses’ knowledge and practice regarding patient care after coronary angiography (CAG) or percutaneous coronary intervention (PCI). This study was conducted to assess nurses’ knowledge and practice on patient’s safety after CAG or PCI and its associated factors.

A descriptive cross-sectional study was conducted from December 2019 to June 2020 at the Department of Internal Cardiology, Interventional Cardiology, Intravascular Intervention, and Intensive care unit/Coronary care unit in three general and specialist hospitals in Ho Chi Minh city, Vietnam. 167 nurses who have taken care of patients after CAG or PCI were included in the study through using convenient sampling technique. A translated self-administered questionnaire was utilised. This self-reported survey achieved 100% response rate. Statistical analysis was performed by the Chi-square test (X2). Statistical significance level was at p<0.05 to determine factors related to nurses’ knowledge and practice. Prevalence ratio (PR) with 95% confidence interval (95% CI) were also used to measure the association.

The study findings revealed that only 36% of the study sample had a good knowledge while 78% of them had a good practice on patient’s safety after CAG or PCI. There were association between educational level, working place with the knowledge (PR=1.87-1.92, p<0.01) and practice (PR=1.18-1.35, p<0.05) on patient’s safety after CAG or PCI among Vietnamese nurses. Besides those factors, the number of years working in cardiac specialty were also found to have an association with the practice. A moderately positive correlation between the knowledge and the practice towards patient’s safety after CAG or PCI has been identified in this study (PR=1.27, 95% CI [1.09 – 1.47], p=0.005).

More than a half of the study sample had poor knowledge but performed good practice in some items of care for patients after CAG or PCI. There was positive association between the knowledge and practice about patient’s safety after CAG or PCI among Vietnamese registered nurses. Educational training programs for staffs working in coronary angiography or percutaneous coronary intervention is recommended to develop.
Prognostic value of AIMS65 score in cirrhotic patients with variceal bleeding
Authors: Huynh Trong Nguyen Dang
Published: December 2021

In cirrhotic patients, variceal bleeding remains a major cause of death. After a variceal bleeding episode, mortality and rebleeding rates spike for the first 6 weeks before levelling off. We aimed to evaluate the performance of AIMS65 score in comparison with Child-Turcotte-Pugh (CTP) score and model for end-stage liver disease (MELD) score in predicting 6-week mortality and rebleeding in cirrhotic patients with variceal bleeding.

Data were collected prospectively from patients with cirrhosis and variceal bleeding at Gastroenterology and Hepatology Department of Cho Ray hospital from September 2016 to April 2017. The primary endpoint was 6-week mortality and rebleeding. The prognostic value of AIMS65, CTP, and MELD scoring systems for 6-week mortality and rebleeding was compared by receiver operating characteristics curves (ROC) and the area under the curve (AUC).

Among 80 patients, 15% rebled and 25% died during 6-week follow-up. AUCROC of AIMS65, CTP, and MELD scores in predicting 6-week rebleeding were 0.68, 0.54, and 0.48, respectively. AUCROC of AIMS65, CTP, and MELD scores in predicting 6-week mortality were 0.80, 0.74, and 0.64, respectively. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of AIMS65 score at the cut-off point of 2 were 95%, 55%, 41.3%, and 97%, respectively.

AIMS65 score is a simple yet applicable tool for risk stratification in cirrhotic patients with variceal bleeding. We recommend using AIMS65 score with a cut-off point of 2 to identify patients at increased risk for 6-week mortality after variceal bleeding.
Validation of a simple HPLC method to quantify methotrexate concentrations in human plasma
Authors: Nguyen Thuan Thi Minh , Nguyen Minh Hue
Published: December 2021

Methotrexate (MTX) is a chemotherapy and immunosuppressive agent widely used to treat cancer, autoimmune diseases in children and adult patients, and ectopic pregnancy. However, MTX is highly toxic to the liver, kidney, and nervous system. This study aimed to quantify the concentration of MTX in human plasma using high-performance liquid chromatography (HPLC). MTX and its internal standard (para aminoacetophenone-PAPA) in plasma samples were extracted simultaneously with methanol. Sample purity was performed using the 1 cc OASIS HLB cartridges. Sample injection volume of 10 μL was analyzed on a Lichrocart Supersil 125-4 column C18 maintained at 40 °C on a Waters 2695 XE equipped with a PDA detector set at 303 nm. The mobile phase contained phosphate buffer (pH 6.0) and methanol at a ratio of 80:20 (v/v) and was maintained at a flow rate of 1 ml/min. The results showed that the total time of chromatographic analysis was 15 min. MTX and PAAP were found in the chromatograms at retention times of 2.3 and 5.2 min, respectively. The linear range of the MTX from 0.5 to 25 μg/mL. Intra-day and inter-day imprecision for MTX ranged from 3.42 to 8.128%. LLOQ of MTX was 0.5 μg/mL and the extraction effects were above 77%. In conclusion, we developed and validated a simple HPLC method to determine the MTX concentrations in human plasma.
Computer-aided structural optimization, synthesis, evaluation of the antimicrobial and cytotoxic activity of some pyrazoline derivatives
Authors: Nguyen Tai Duc , Ly Du Nguyen Hai , Do Tuoi Thi Hong , Huynh Phuong Thi Ngoc
Published: December 2021

In the last few decades, pyrazoline-based substances have emerged as potential antimicrobial and anticancer candidates. In concern with antimicrobial activity, this study aims to build a docking model to predict the structure of potential 2-pyrazoline derivatives. The cytotoxicity of some compounds was also evaluated to get insight into the structure–anticancer activity relationship of the 2-pyrazoline derivatives.

Docking models were built on virtual FabH enzymes using FlexX platform with 2-pyrazoline derivatives served as test sets. Afterward, derivatives with high docking scores were chemically synthesized and evaluated for antibacterial activity using the agar dilution method. Furthermore, MTT assay was used to assess the cytotoxicity of these compounds.

The docking score and the in vitro minimum inhibitory concentration (MIC) value on Staphylococcus aureus (S. aureus) bacteria strongly correlate with an R-square value of 0.6751 (p < 0.0001). Four 2-pyrazoline derivatives were synthesized and evaluated for antimicrobial activity. Their MIC values on S. aureus range between 4 and 16 μg/mL, consistent with ones predicted by the docking model. Apropos cytotoxic properties, a series of 2-pyrazolines exhibit a moderate activity on HepG2, RD, and MDA-MB-231. The most active compound, HP10, has the IC50 values on these cell lines. which are 26.62 μM, 17.74 μM, 14.47 μM, respectively.

Our research built a docking model on the virtual S. aureus FabH enzyme with high potential in predicting antibacterial activities of different 2-pyrazoline derivatives. Moreover, our cytotoxicity results provided data for further studies on the anticancer activity of these promising derivatives.
The Actualized Development of Information Economy in the Context of Global Transformations
Authors:   Ukrainian Engineering and Pedagogical Academy, Chobitok V. I. , Biryukova К. V. ,   Ukrainian Engineering and Pedagogical Academy, Starenkov D. O. ,   Ukrainian Engineering and Pedagogical Academy
Published: December 2021

The purpose of the article is to form scientific and practical aspects of actualization of the development of the information economy in the context of global transformations. According to results of the study, one can say that modern information technologies have come a long way in their development, but they need further improvement. It is already clear that the future, for effective managerial decisions, envisages attraction of not only human capital, but also breakthrough technologies and artificial intelligence. Accordingly, most countries over the world associate their development strategy with the transition to the information economy. The greatest success in the transition to the information economy reached developed countries, including the United States, Germany, France, Great Britain, China, and Japan. Regrettably, Ukraine today occupies a low position in the world rankings regarding indicators influencing the process of actualizing the development of the information economy in the context of global transformations. Although recently in Ukraine there have been infrastructure changes in the direction of computerization and informatization, the degree of their influence both at the domestic level and at the level of corporate sectors is increasing, the number of innovative enterprises is actively growing. The essence of the information economy consists in the formation of elaborate, complex phenomena that are associated with changes in the system of productive forces and social relations directed towards the effective and rational use of information technologies and creative work. Overcoming existing problems will provide an opportunity to actively develop the information economy of Ukraine in the context of global transformations. In general, the policy of development of information economy should be comprehensive and create the necessary conditions for the corresponding transition: economic, legal, and organizational.