bluuebunny/crossref_metadata_2025 huggingface dataset:
Nano-CuOx for ciprofloxacin effective removal via wet peroxide oxidation catalysis and its practical application in wastewater
Authors: Liu Dan , Shi Changping , Nie Yang , Peng Wenjun , Ming Yin-an
Published: November 2022

Using Cu(NO3)2·3H2O as active material and citric acid (CA) as complexing agent, heterogeneous catalyst nano-CuOx was prepared by sol-gel method. The catalytic wet peroxide oxidation (CWPO) reaction system was established accordingly. The system was used to treat ciprofloxacin (CIP) in simulated wastewater and real wastewater. The effects of the molar ratio of metal salt to CA, calcination temperature, H2O2 dosage, reaction temperature, and catalyst dosage on the physicochemical structure and the properties of CWPO were investigated. The results showed that when the molar ratio of CA to metal salt (Cu(NO3)2·3H2O) was 1.8, the calcination temperature was 500 °C, the concentration of H2O2 was 10 mmol · L–1, the reaction temperature was 95 °C, and the dosage of catalyst was 1 g · L–1, CWPO system has the best degradation effect on CIP. At thses optical conditions, the removal rate reached 86.8%, chemical oxygen demand (COD) removal rate reached 54.9%, and the recycling rate of the catalyst was very good. The refractory organics in actual pharmaceutical wastewater could be oxidized by this system as well, and the COD removal rate reaches 47%. The degradation mechanism of CIP showed that the main functions of the CWPO system were ·O2– and ·OH radicals. The possible degradation pathways were determined by ion chromatography to be intermediate products generated from piperazine ring cleavage, defluorination, decarboxylation, and quinoline hydroxylation of CIP. The catalyzing mechanism was investigated in detail; some useful information was obtained in this work.
Musculoskeletal physiotherapists reasons for treatment selection and continuous professional development practices in the United Kingdom: A cross-sectional survey
Authors: Chesterton Paul , Skidmore Nathan
Published: November 2022

PURPOSE: The aims of the study were two-fold 1) to explore the treatment modalities musculoskeletal physiotherapists are utilising and the underlying reasons why and 2) report current continuing professional development (CPD) practises and their perceived effectiveness. METHODS: Using a cross-sectional questionnaire, musculoskeletal physiotherapists in the United Kingdom (UK) were invited to complete an online survey. The survey captured respondents’ professional characteristics and their main reason for selecting a range of treatments sub-grouped into three broad categories; Manual Therapy, Treatment Modalities and Education Based Approaches. Respondents were asked to report their CPD practises and their perceived effectiveness. Data was converted into proportions with lower and upper limits of the 95% confidence interval (CI). Likert scale questions were treated as numeric variables with the mean and standard deviation (SD) calculated for combined responses. RESULTS: Of the 414 responders, 408 were eligible for analyses. The most common reason for treatment selection, based upon a combined total of 9792 responses across all treatment modalities, was content taught in ‘entry-level training’ (n = 2010, 20.5%, 85% CI 20 to 21), followed by ‘practice related courses or CPD events’ (n = 1241, 12.7%, 95% CI 12 to 13). ‘Self-reflection’ was the most common form of CPD (n = 404). All forms of CPD were considered ‘effective’ for developing knowledge and skills except ‘clinical audit’ and ‘journal clubs’ which were rated as ‘indifferent’ by respondents. CONCLUSIONS: Treatment technique depends heavily on skills taught in entry-level training. Despite research articles amongst the most utilised forms of CPD, a disconnect exists in its implementation as the main driver of treatment selection. A wide range of CPD activities were undertaken by participants and rated as ‘effective’ for acquiring and applying physiotherapy related skills.
Follow-up of brace-treated scoliosis in children with cerebral palsy and spina bifida
Authors: Eek Meta N. , Blomkvist Annika , Romberg Karin
Published: November 2022

PURPOSE: This study aimed to describe brace use, progression of scoliosis, and surgery in children with cerebral palsy (CP) and spina bifida (SB) who were initially treated with a brace. METHODS: Medical records were retrospectively analysed for brace compliance, treatment complications, curve size measurements with and without the brace at both start and at follow-up, and number of patients undergoing spine surgery. RESULTS: Sixty-eight children were included (CP 47, SB 21), 37 of whom were girls, with a mean age at start of treatment of 11.1 (CP) and 8.2 (SB) years. Most had severe motor problems; only four children with CP and five with SB were able to walk. Thirty-five in the group with CP and 11 in the group with SB had a curve size over 40°. Forty used the brace full-time, 19 half-time and nine for a varying proportion of time. Transient complications of brace treatment were seen in 28%. The yearly progression of curve-size was 4.2° in CP and 2.3° in SB. Twenty-eight patients underwent surgery and complications were present in 75% of these patients. Twenty-seven out of 46 patients with severe scoliosis did not undergo surgery. CONCLUSION: Brace treatment was possible, even in patients with severe scoliosis. Bracing can delay the progression of scoliosis.
Association of ethnicity and adaptive functioning with health-related quality of life in pediatric myelomeningocele
Authors: Kamath Navya N. , Kulesz Paulina A. , Fletcher Jack M. , Houtrow Amy J. , Treble-Barna Amery
Published: November 2022

PURPOSE: The purpose of this study was to evaluate associations of ethnicity and adaptive function with health-related quality of life (HRQOL) in youths with spina bifida myelomeningocele (SBM). METHODS: Participants included Hispanic (n = 75) and non-Hispanic White (n = 86) children and adolescents with SBM. Participants completed ratings of adaptive function and SBM-specific HRQOL. A series of linear multiple regression models was computed to investigate whether ethnicity moderates the relation between adaptive function and HRQOL. RESULTS: Results showed that greater adaptive function was associated with higher HRQOL. While no relations were found between ethnicity and HRQOL, a significant interaction was observed between adaptive function and ethnicity over and above other terms. Although groups did not differ on HRQOL at lower levels of adaptive function, Hispanic participants rated higher HRQOL relative to non-Hispanic White participants at higher levels of adaptive function. Further analysis showed this was true of both nonmotor and motor aspects of adaptive function. CONCLUSION: Results suggested complex relations between ethnicity and adaptive function with HRQOL, highlighting the importance of optimizing adaptive functioning in youth with SBM.
National work-family policies: Multilevel effects on employee reactions to work/family conflict
Authors: Bettac Erica L. , Probst Tahira M.
Published: November 2022

BACKGROUND: Despite considerable differences in national work-family (WF) policies offered in countries around the world, research concerning the implications of such policies for employee reactions to work-family and family-work conflict (WFC/FWC) is limited. OBJECTIVE: The current study examines the contextual role of country-level national WF policies as a moderator of the relationships between individual-level WFC/FWC and job stress, job satisfaction, turnover intentions, organizational commitment, and general health. METHODS: Using archival data sources, the ISSP Work Orientations Survey (2015) and the WORLD Policy Analysis Center Adults Labor Database (2014), multilevel analyses tested the predicted cross-level interaction effect in a sample of 49,637 individuals (54% female; Mage = 48 years) nested across 36 countries. RESULTS: Results were largely counter to expectations: while more supportive national WF policies attenuated the positive relationship between FWC and job stress, it exacerbated the negative relationships between WFC and organizational commitment, WFC and job stress, and FWC and general health. CONCLUSIONS: Our study responds to calls to consider phenomena functioning at multiple levels of analysis. While reactions were more negative in countries with more robust national-level policies, it suggests an unexpected dark side of such policies. That is, it may not be enough to legislate the availability of national-level policies; it may also be needed to ensure that such policies are meeting employees’ needs.
Workplace accommodation in return to work after mild traumatic brain injury
Authors: Spjelkavik Øystein , Enehaug Heidi , Klethagen Pål , Howe Emilie Isager , Fure Silje C.R. , Terjesen Hans C.A. , Løvstad Marianne , Andelic Nada
Published: November 2022

BACKGROUND: While a vast amount of research focuses on unmodifiable and individual factors that may impact return to work (RTW) for patients with traumatic brain injury (TBI), less knowledge exists of the relationship between specific workplace factors and work retention. OBJECTIVE: Identify types of accommodation in the workplace that influence the RTW process for employees with TBI and the challenges associated with them. METHODS: A multiple case study consisting of 38 cases and 109 interviews of employees with TBI and their managers conducted between 2017 and 2020 at two time points. RESULTS: Accommodation of both the organizational and psychosocial work environment influences RTW for employees with TBI. Social support and supportive management may have positive and negative effects. RTW is often not a linear process. Over time, maintaining and developing customized accommodation in the work organization is challenging. CONCLUSIONS: Uncertainty about accommodation in RTW for employees with TBI is closely linked to lack of knowledge in the workplace of how to handle complex and nonlinear RTW processes. Work-oriented rehabilitation should to a greater extent provide managers with relevant information and support to develop the person-environment fit over time.
Pengenalan dan Praktik Saham Berbasis Syariah Sebagai Pilihan Investasi Di Tengah Pandemi Kepada Guru-guru MTs N 4 Karawang
Authors: Diana Nana , Kristamtomo Putra Raden Aditya , Ridha Azhari
Published: November 2022

Data lima tahun terakhir (2015-2019), jumlah saham syariah terus mengalami peningkatan dari tahun ke tahun. Jumlah saham syariah pada  tahun 2015 sebanyak 331 saham. Data per periode 1 tahun 2020 jumlah saham syariah mencapai 470 saham. Pelatihan dan praktik ini dilakukan secara daring kepada guru-guru MTs N 4 Karawang. Dilakukan survei melalui googleform setelah kegiatan berlangsung. Sebelum adanya webinar praktik saham syariah statistik pengetahuan peserta adalah 34% dari peserta menyatakan berada di rentang 1. 24% peserta menyatakan berada di rentang 2. 19% peserta menyatakan berada di rentang 3. 7% peserta menyatakan berada di rentang 4. Serta 16% peserta menyatakan berada di rentang 5. Sedangkan setelah adanya webinar praktik saham syariah menghasilkan hasil perbedaan yang cukup signifikan yaitu 3% dari peserta menyatakan berada di rentang 1 dan juga rentang 2. 24% peserta menyatakan berada di rentang 3. 44% peserta menyatakan berada di rentang 4. Serta 26% peserta menyatakan berada di rentang 5. Hasil dari kusioner survei peserta rangkaian webinar saham syariah tersebut menjelaskan bahwa adanya dampak  yang cukup signifikan untuk pengedukasian kepada Guru MTs 4 Negeri Karawang, mahasiswa, dan masyarakat umum sebagai peserta dari rangkaian webinar mengenai pengenalan dasar teori dan implementasi transaksi saham syariah.
Pemanfaatan E-Commerce dan Sistem Informasi Akuntansi Pada Usaha UMKM Pasca Pandemi Covid 19 Di Desa Dukuh Dempok, Kec. Wuluhan, Jember
Authors: Suharsono Riyanto Setiawan , Azhad Naely , Santoso Budi
Published: November 2022

The development of science and technology through the use of E-Commerce and Accounting Information Systems in the business world, especially in Micro, Small and Medium Enterprises (MSMEs) has increased in recent years. E-Commerce which is a buying and selling activity through electronic media allows it to be carried out by business actors and the public even though they have limited capital. The financing network, business network as well as MSME business competition which are quite extensive and growing also require adequate Accounting Information System facilities to collect transaction data, make decisions and supervise the organization. The ability to absorb labor from MSMEs is also quite large. This makes MSMEs have an important role in the economy of a region. The emergence of the Covid-19 Pandemic in early 2020, whose impact is still being felt in 2021, has raised various problems due to reduced income for most people in general. All MSME sectors are affected by the Covid-19 Pandemic. For this reason, innovations are needed in increasing people's income through the use of E-Commerce and Accounting Information Systems to increase the business potential of MSMEs.

This Service Program seeks to provide answers and solutions to problems faced by some small communities and MSME business actors who are affected by the Covid-19 Pandemic and are not familiar with technological developments. Based on the problems faced by the community, the service that will be carried out is to provide training and education to the community and MSME actors in Dukuh Dempok Village, Kec. Wuluhan, Jember. This community service method uses seminars/workshops, practices and discussions with MSME actors in Dukuh Dempok Village, Kec. Wuluhan, Jember
Implementasi Netralisator Uv-C Dalam Upaya Mengurangi Airborne Disease Di Pondok Pesantren Ar-Ridwan Al-Maliky Bojonegoro
Authors: Akhmad Al-Bari  , Abdul Basith
Published: November 2022

Pendidikan pondok pesantren yang merupakan hasil perjuangan ulama bertujuan memperdalam al-Quran, hadist, kitab ulama salaf dan khalaf. Ar-ridwan Al-maliky adalah salah satu pondok pesantren yang berdiri pada 2016 di Bojonegoro dengan jumlah santri semakin meningkat. Namun di tahun 2020 wabah covid-19 menyebar hingga ke lingkungan pesantren sehingga kegiatan pesantren terganggu. Telah Banyak upaya yang dilakukan pesantren untuk mencegah penyebaran penyakit ini diantaranya dengan disinfeksi lantai, dinding, dan lain-lain. Namun upaya tersebut tidaklah cukup karena penyakit dapat menyebar melalui udara (airborne). Sinar Uv-C memiliki energi tinggi yang dapat berfungsi membunuh virus dan bakteri dengan cepat yang efektif, sehingga berpotensi sebagai netralisator udara. Model pengabdian yang dilakukan dengan metode partisipatif. Santri ikut mengimplementasikan netralisator di ruang berkumpul, kemudian diadakan sosialiasi kerja alat, dan penggunaan yang diakhiri evaluasi. Hasil evaluasi menunjukkan terdapat perubahan udara ruangan selama satu minggu ditandai dengan kesegaran santri meningkat. Sedangkan pemahaman santri tentang penggunaan dan penanggulanan alat menunjukkan respon baik diatas 80%.
Teknologi SMAW Untuk Kebutuhan Proses Fabrikasi Produk Bidang Pengelasan Pada Masyarakat Pedesaan di Sektor Pertanian
Authors: Noorsakti Wahyudi  , Alfi Tranggono Agus Salim  , Yosi Afandi  , Imam Mudofir  , Wida Yuliar Rezika  , Nurudin  , Tania Setya Ningsih  , Rafael Slamet Firdaus  , Mega Rahayu Nur Kusuma Wardhani
Published: November 2022

Abstrak

 

Pertanian adalah sektor utama di Desa Bader, Dusun Kayang Makmur, Kabupaten Dolopo, khususnya pada RT 16, RW 06. Alat bantu pertanian mayoritas berbahan logam yang dapat aus, korosi, dan patah. Kerusakan/patah pada alat pertanian berbahan logam, seperti cangkul, bajak, dan sabit lebih efektif dilakukan perbaikan dengan pengelasan SMAW Aplikatif. Kerusakan alat pertanian umumnya bisa diposisikan secara horizontal karena bisa dilepas dari komponen lainnya, sehingga posisi pengelasan yang mudah dan sesuai adalah 1F dan 2F. Penerapan teknologi bidang pengelasan dilakukan secara teori dan praktek dalam kegiatan Program Kemitraan Masyarakat (PKM). Metode pelatihan mengadopsi dari IPTEK yang diterapkan pada perkuliahan di Politeknik Negeri Madiun. Pengabdian untuk menghasilkan luaran peserta yang mampu memperbaiki alat pertanian berbahan logam, dan membuat produk berbahan dasar logam dengan proses pengelasan SMAW.

 

Kata kunci—  Dusun Kayang Makmur, Pertanian, Pengelasan Aplikatif, SMAW, Program Kemitraan Masyarakat
Terapan Metode Pengelasan Dasar GMAW Gasless untuk Peningkatan Keterampilan Masyarakat Dusun Kayang Makmur, Desa Bader, Kabupaten Madiun
Authors: Alfi Tranggono Agus Salim  , Achmad Aminudin  , Nanang Romandoni  , Muhamad Fajar Subkhan  , Fachrudin Muhamad Rizki Fachrudin , Radiffa Aditama  , Mochamad Reza Arimurti  , Elza Febri Yusdetira
Published: November 2022

Abstrak

Masyarakat Dusun Kayang Makmur sebagian besar telah menggunakan peralatan pertanian yang terbuat dari baja. Alat pertanian tersebut dibutuhkan perawatan dan perbaikan dengan menggunakan teknik pengelasan. Dalam melakukan pengelasan tersebut harus dilakukan sesuai dengan prosedur pengelasan yang benar, instalasi alat yang tepat, dan pemahaman yang baik mengenai Keselamatan dan Kesehatan Kerja (K3) sehingga efektivitas dari pengelasan dapat dicapai dengan maksimal. Oleh karena itu, diadakan pelatihan pengelasan dasar GMAW Gasless guna meningkatkan keterampilan Masyarakat Dusun Kayang Makmur. Penyelenggaraan program kemitraan masyarakat ini dilaksanakan dengan beberapa parameter dengan luaran dari kegiatan ini berupa kemampuan teknik pengelasan dasar GMAW Gasless metode 1F dan 2F. Tahapan pelaksanaan terdiri dari teori pengelasan, K3, serta praktek dan pendampingan pengelasan dasar yang menghasilkan produk berupa kursi. Hasil dari pengabdian pengelasan ini adalah peningkatan pengetahuan dan kemampuan peserta hal pengelasan dasar GMAW Gasless, serta dapat menerapkan proses pengelasan dengan mengutamakan K3.

 

Kata Kunci- Program Kemitraan Masyarakat, Dusun Kayang Makmur, Pengelasan, GMAW Gasless.
Evaluation of future technology teachers’ readiness for anticipatory vocational training of schoolchildren
Authors:   Kazan Federal University, Kashfrazyeva Gulnara K. , Sedov Sergey A. ,   Kazan Federal University
Published: November 2022

Introduction. Professional self-identification of schoolchildren on the 5th-9th years of training should be attributed mainly to the result of technology teacher’s career guidance work. However, the due training of technology teachers themselves in this domain is not paid enough attention to in the theory and practice of higher educational establishments. The focus of the present publication is assessment of such readiness in students – future technology teachers – and development of recommendations for higher educational system on the basis of the obtained results. The purpose of this study is the evolution of future technology teachers’ readiness for anticipatory vocational training of schoolchildren. Materials and methods. The questioning involved 120 respondents, future technology teachers (3rd-5th year students trained under the programme of higher pedagogical education in the profile “Technology”) from 5 state universities of Moscow, St. Petersburg, Novosibirsk, Nizhny Novgorod and Kazan (Russian Federation). The original questionnaires were developed with the use of Google Forms tools. The statistical data processing method was Pearson’s chi-square test. The research was based on the application of theoretical methods: analysis (relative to the semantics of the concept “teacher’s readiness for advanced vocational training of a schoolchild”), synthesis (essential categorial characteristics of teacher’s readiness for anticipatory vocational training of schoolchildren), comparison (theory and practice in higher education system), specification (key provisions), modelling. Results. A total of 92% of the 3rd-5th year students are aware of the need for anticipatory vocational training of schoolchildren. At the same time, only 66% of the respondents (from 50% on the 3rd year to 75% on the 4th-5th year) consider themselves ready for such schooling. The analysis of the questioning results of students who answered in a different way made it possible to reveal the causes of educational deficiency. These reasons were interpreted as components of the work offered by us for the university system for integration into the programme of higher pedagogical education in the profile “Technology”. On the 4th-5th year students feel ready for advanced vocational training (p<0.01). Conclusion. Students’ – future technology teachers’ self-assessment of readiness for anticipatory vocational training of schoolchildren made it possible, on the one hand, to affirm the formation of such readiness as a pedagogical problem and, on the other hand, to identify the growing points for elimination of the identified educational deficiency in the higher education system.
The Perception and Resilience of Bagang Community on Climate Change in Marine Protected Area, Pitas, Sabah, Malaysia
Authors: FOO JURRY
Published: November 2022

Climate change had caused occurrence of more frequent big El Nino and La Nino phenomenon that led to drought and flood disasters onto coastal communities and affecting their quality of life.  This study aims to ascertain the perceptions of the coastal community of Kampung Mempakad Laut, Pitas, Sabah, Malaysia which is in the boundary of Tun Mustapha Park on climate change. Data is collected through in-depth interviews with the Bagang community and the data was analysed by descriptive methods. The Bagang community members have knowledge and is aware of the changes in the climate conditions through the happenings of extreme event orchestrated by mother nature that relates to the change in climate phenomena despite not knowing or not familiar with the well-used terms ‘climate change’. Examples of those extreme events are major floods, changes in dry and wet seasons, as well as long unpredictable dry season. They perceive those events as pressure that ultimately threatens their safety and affects Bagang activities. However, they have come up with their own strategies in adapting to the phenomena including precautionary and preparatory measures for enduring natural disasters, modifications of dwelling houses, attempts to increase understanding and cognisance of the changes in environmental surroundings enabling them to come up with better predictions. The experience and resilience of Bagang community that had endured extreme events related to climate change had provided further insights in understanding human’s adaptations to climate change and could become useful guidelines to other coastline communities at large.
Pendampingan Pengembangan Usaha Bawang Goreng Kemasan Pada Umkm Desa Banjaragung Kabupaten Jombang
Authors: Wicaksono Agung Prasetyo Nugroho , Soelistyo Aris
Published: November 2022

Mitra pengabdian yaitu UMKM warga RT 26 RW 10 Desa Banjaragung Kecamatan Bareng Kabupaten Jombang yang bergerak di produksi bawang goreng kemasan. Peran dari kegiatan pengabdian yang dilakukan adalah memberikan pelatihan berbasis komputerisasi untuk pembuatan laporan cash flow sederhana agar mitra mampu memberikan informasi yang transparan dalam penggunaan aliran dana usahanya. Mitra selama ini tidak mampu memisahkan secara pasti dana pribadi dengan dana usahanya, maka kegiatan pengabdian ini merupakan solusi yang tepat untuk mengatasi permasalahan mitra. Metode yang dilakukan adalah dengan melakukan sosialisi konsep cash flow dan melakukan simulasi program laporan cash flow sederhana dengan program Ms. Excel.
Workshop Daur Ulang Kertas Bekas Sebagai Upaya Menanamkan Karakter Peduli Lingkungan Pada Siswa SMP Darul Ulum 2 Jombang
Authors: Dinarti Siti , Mahatmaharti Agung Kesna
Published: November 2022

Kertas adalah salah satu limbah yang paling banyak dihasilkan oleh manusia, baik yang dihasilkan oleh rumah tangga maupun sekolah dan perkantoran. Pada umumnya sebuah akademik akan menghasilkan limbah kertas yang cukup besar karena segala kegiatan akademik berhubungan langsung dengan kertas. Berbagai upaya untuk mengurangi sampah kertas bekas sudah dilakukan, yakni dengan menggunakan metode 3R atau Recycle, Reuse, dan Reduce. Dimanapun tempatnya sering terjadi penumpukan sampah Kertas dikarenakan rendahnya kepedulian masyarakat dalam kegiatan pengolahan sampah. Rendahnya kepedulian masyarakat dalam kegiatan mengelola sampah di lingkungan sekitar merupakan salah satu bentuk kurangnya kesadaran manusia dalam menjaga lingkungan. Perlu dilakukan suatu gerakan yang dapat menumbuhkan kesadaran untuk lebih peduli terhadap lingkungan. Gerakan ini dapat dilakukan dengan cara menanamkan pendidikan karakter peduli lingkungan sedini mungkin kepada siswa. Pendidikan karakter peduli lingkungan yang ditanamkan kepada siswa diharapkan dapat memberikan dampak positif terhadap cara berpikir dan perilaku siswa dalam menjaga lingkungan sekitar. Pelaksana melakukan pengabdian kepada masyarakat di SMP 2 Darul Ulum Jombang. Kegiatan workshop dilakukan dengan menggunakan metode observasi, ceramah, tanya jawab dan demonstrasi. Hasil evaluasi menunjukkan bahwa kegiatan workshop ini dapat meningkatan kepedulian lingkungn pada siswa, siswa juga antusias dalam mempraktikan proses daur ulang kertas bekas menjadi barang yang bernilai guna.
Business Strategy Training for "Yuni Phea" Sewing Business Housewives Group in South Siantar District, Pematang Siantar City
Authors: Butarbutar Marisi , Sudirman Acai , Windarto Agus Perdana , Chandra Erbin , Sinaga Onita Sari
Published: November 2022

The substance of the problems faced by partners, one of which relates to aspects of human resource communication. The group of housewives who are members of the community group "YUNI PHEA" still holds on to their own egos and finds it difficult to work as an effective team, participants still prioritize individual interests (super man) and sometimes ignore the importance of working as a team (super team). In addition, the production capacity produced by the group of housewives is still limited due to production equipment such as sewing machines which are still inadequate in terms of quantity and quality and members still use the machines owned by their fellow members and are old enough to cause limitations in terms of production and market. share that has not been clearly identified and promotional efforts that have not been optimal. Indicators of the success of this service activity include increased production capacity by 90%, production results are neater and have quality variations, increased partner turnover of at least 90%, and increased business competitiveness of at least 90%.
Pemanfaatan Limbah Bekas (Rongsokan) Sebagai Penghasilan Utama Masyarakat Desa Panguragan Cirebon
Authors: Wibisono Dhika Dzulkarnain , Ariyani Dewi
Published: November 2022

The purpose of this article boils down to the potential of the village in recycling used Rogsokan goods to become the main source of income for the Panguragan village community, Cirebon. Where people collect junk from various regions and resell it to large manufacturers, so it's not surprising that many people run this business and make it the big boss who can be said to be able to lift the economic sector of the community. The results of the observations showed positive results where the economy was better in Panguragan village as a place for collecting used junk in Cirebon district where this made Panguragan called the rongsok village
Development of a Conceptual Framework for Relationships between Social Media Marketing and Intentions to Stay at Five-Star Hotels
Authors: Dewi Nyoman Indah Kusuma , Adiningrat Gede Pradiva , Wirga I Wayan , Putra Upayana Wiguna Eka , Sukartini Ni Wayan
Published: November 2022

Data shows that social media users continue to increase worldwide, particularly in Indonesia, and the time they spend accessing social media. There are 191.4 million active users of social media in Indonesia. The average time spent accessing social media is 3 hours 17 minutes per day, which is higher than the world average, i.e., 2 hours 27 minutes. Research has been conducted on using social media as a marketing tool in the hotel industry. Still, no study assessed the star hotel consumers'' perceived usefulness and trust of social media marketing activities, including the celebrity effect of endorsers and intention to stay or buy services provided by star hotels (purchase intention). Celebrity endorsers are a new phenomenon in social media marketing. By looking at this phenomenon, this research aims to investigate: (1) the factors that influence the relationship between social media marketing and the intention to stay at the hotel and (2) the social media marketing concept framework that influences hotel stay intentions. This study uses a combination of Sequential Explanatory research methods. In the first stage, quantitative methods were used to draft a Conceptual Framework for the Relationship between Social Media Marketing and Intentions to Stay at Star Hotels. In the second stage, qualitative methods were used to validate the conceptual framework. Findings reveal that all indicators, i.e., advertisements, celebrity effects, customization, e-WOM, entertainment, interaction, trendiness, perceived trust, and perceived usefulness, are relevant and relate to purchase intention to stay in a hotel.
Prevention of Income and Profit-Shifting to Tax Haven Countries in Nigeria
Authors: Sa’Adu Hafsat Iyabo , Isau Ahmed Olatunji
Published: November 2022

One of the major strategies usually employed by companies to avoid taxation in Nigeria is to shift their incomes or profits to their subsidiaries located in low or no tax countries, usually referred to as ‘tax haven countries’. This is a result of the globalisation of international trade which made it possible for companies to extend their businesses to countries other than where they are headquartered. Thus the article examines income and profit-shifting to tax haven countries, its international regulations as well as its regulations in Nigeria. The article found that Nigeria does not have an adequate legal framework to prevent companies from shifting incomes and profits to their tax haven subsidiaries. The article recommends that the Nigerian government should urgently put in place the necessary legal framework and administrative procedures to implement the Organisation for Economic Co-operation and Development (OECD) 15-Action Plan on Base Erosion and Profit Shifting (BEPS) in line with international best practices.
The United Nations Declaration of Human Rights 1948: Successes and Challenges
Authors: Wilson Tamfuh Y. N.
Published: November 2022

This article looks into the successes and challenges of the United Nations Declaration of Human Rights (the Declaration) 1948. Too often the approach of its failures has been explored over the years, but the author believes it is a herculean task to maintain and promote world peace and universal human welfare, so those steps taken in obedience and application of the Declaration need to be unravelled and appreciated. The unity and coexistence among states, the creation of subsidiary organs, the installation of good governance in many countries, the internationalisation of constitutions and uniform judicial decisions in national and regional courts are all recorded as successes of the Declaration in this article. The challenges of the Declaration are also explored in this work, such as the modern forms of slavery still practised in many parts of the world, the controversy of international criminal justice, violence against women and the claim to extreme rights. The author analyses these challenges and gives recommendations for a better future in the application of the Declaration.
Le Mariage heureux du féminisme et du néolibéralisme: pistes pour analyser une union récente
Authors: Delage Pauline
Published: November 2022

By tracing the transformations of gender-based violence policies in France, this article highlights how they reflect neoliberal feminist dynamics. While the notion of ‘neoliberal feminism’ was developed to focus on the cultural and symbolic arena to analyse the changing representations of feminism, as well as the norms and subjectivities that were shaped by both a managerial and an egalitarian ethos, the role of the state in these processes was left aside. Therefore, the article aims at putting the state back into the analysis of neoliberal feminism by showing how state feminism has been driven in part by a neoliberal rationale when designing policies and has progressively excluded a structural perspective on the problem of gender-based violence.
Vanessa Springora, Gabriel Matzneff and the Problem of Consent
Authors: Morrey Douglas
Published: November 2022

The publication of Vanessa Springora’s Le Consentement in January 2020, which led to the public shaming of the paedophile writer Gabriel Matzneff, has been seen as a key #MeToo moment in French culture. In her account of her adolescent relationship with Matzneff, Springora stops short of condemning all sex with minors and does not call for any strengthening of French laws around sexual consent. Does this imply a misplaced confidence, arguably shared by some strains of postfeminist thought, in young girls’ sexual agency and resolve? And is this, in turn, complicit with Matzneff’s own romanticized account of adolescent sexuality? I suggest, instead, that Springora frames her account in terms of consent precisely in order to suggest – as a number of feminist critics have recently done – the inadequacy of consent discourse as a means of protecting young women and girls within a patriarchal culture. Rather, Le Consentement stands as a redressing of the discursive balance within a literary and extra-literary system of representation that, for some six decades, worked to legitimize Matzneff’s compulsive desire for young girls and boys while disregarding the damage inflicted by the subjective experience of those young people.
Anti-Inflammatory and Antioxidant Effect of Various Extracts of Coleus forskohlii Root
Authors: Mary P. Philomina , A. Malarvizhi
Published: November 2022

Currently, medicinal plants are attracting a great deal of interest as sources of chemicals with antioxidant and anti-inflammatory characteristics. Concerning inflammatory processes and oxidative stress, we evaluated the possible therapeutic benefit of several extracts (methanolic, ethanolic, aqueous, and chloroform) of Coleus forskohlii root. This research used the in vitro antioxidant model as DPPH radical scavenging and anti inflammatory action as protein denaturation and HRBC membrane lysis. For this objective, a rather novel strategy based on the measurement of anti-inflammatory and antioxidant characteristics in combination was used. Using in vitro models, the methanolic extract of Coleus forskohlii root has the highest antioxidant and anti-inflammatory activity, followed by ethanol, aqueous, and chloroform extracts. The root of Coleus forskohlii might serve as a promising material for the creation of innovative and safer plant-based anti-inflammatory and antioxidant medicines.
Studies on the Pistia stratiotes Reduction of Acute Toxicity of Malathion on Growth and Protein Content in Fresh Water Fish Catla catla Fingerlings
Authors: Nisha S. Nazerath , P Anusuya
Published: November 2022

The primary objective of this research was to examine the effect of malathion exposure on growth and protein content in Catla catla fingerlings (3.87±0.10 g). Malathion's 96 h LC50 value for fingerlings of C. catla was 10.0 µl/l. There was no mortality below the concentration of 9.5 µl/l. During 24, 48, 72, and 96 h, the growth and biochemical composition of fish of control group were significantly greater than those of the malathion-treated groups. The conclusion is that both low and high amounts of malathion are very harmful and affects vital organs of fish. Experiment was performed to examine the growth and protein content of fingerlings of Catla catla exposed to malathion for eighty days. During this experiment, the fish were fed Water Lettuce, Pistia stratiotes young leaf meal at various concentrations as a control diet (0% P. stratiotes) and experimental diets containing 10%, 20%, 30%, 40% and 50% of P. stratiotes in place of fish meal as a protein source and designated as P0, P10, P20, P30, P40, and P50, respectively. There was a statistically significant difference (P <0.01) between growth and protein content. The findings also shown that malathion-exposed fingerlings of C. catla fed meals containing up to 30% P. stratiotes meal performed the best among experimental diets. Although fish meal is irreplaceable, aquatic weed meal may be added up to the optimal quantity to make cost-effective feed for C. catla.
Isolation and Characterization of Bio-surfactant Producing Bacteria
Authors: R Nirmalkumar , S. Uma , Parameswaran Indumathi
Published: November 2022

Oil spillages are so common in many fields which lead to contaminated soil. Soil polluted land filling contains bacteria that produce a broad spectrum of bio-surfactants. Bio-surfactant as an efficient biological surfaceactive agent may provide an alternative solution for the removal of heavy metals from industrial wastes. The biosurfactant has more potential efficiency in the process of remedying natural resources. Surfactin, Iturin and Fengycin are widely studied bio-surfactants. The present study was aimed to isolate and characterize the biosurfactant producing bacteria from the soil samples collected from the petrol bunk. Two isolates obtained were used for the further analysis. Catalase, Lactose fermentation, Citrate utilization tests were positive for isolate 1 and identified as Staphylococcus sp. Starch hydrolysis, Methyl red test, Catalase, Lactose fermentation, Citrate utilization tests and Nitrate reduction were positive for isolate 2 and identified as Bacillus sp. The samples were anlayzed for the Bio-surfactant property using Haemolytic activity, oil drop assay, oil collapse activity and emulsification test. The functional group was detected using the FTIR analysis. Bacillus sp. strains have more potent biosurfactant property than Staphylococcus sp. and they act as bio-surfactants in removing the stains. Biochemical characterization of isolated samples, determination of bio-surfactant producing organism by oil spreading activity, drop collapse assay, oil spreading activity and biofilm formation were confirmed by Bacillus species bacteria
Copper Deficiency and Central Nervous System
Authors: Rajendra Kurup Ankita , Nair Neena
Published: November 2022

Copper, a microelement essential for all living organisms, is involved in normal physiological functioning of numerous enzymes. In central nervous system, it is involved in various metabolic pathways besides its involvement in mitochondrial activity, defense against oxidative stress, myelination, neurotransmitter synthesis and storage as well as modulation of synaptic activity. Homeostasis of copper is achieved by copper transporters, metallo-chaperones as well as exporters which prevents both deficiency and accumulation of this element. Acquired copper deficiency is rare but alterations in lifestyle and eating habits have made this rare deficiency more prevalent. Studies have linked copper deficiency to various neurodegenerative diseases including Alzheimer’s and Parkinson’s. Copper deficiency in central nervous system is also associated with myeloneuropathy. This review assesses the impact of copper deficiency on the central nervous system.
Extensive Development and Evaluation of a Polyherbal Wholesome Dermal Cream
Authors: Manish Kumar Gupta , Sujit Nagare , Birendra Shrivastava , Supriya Hyam , Ketaki Dhane
Published: November 2022

Ayurveda is plant-based system of medicines which is developed through daily life experiences. Now-adays the interest in plant-based drugs has been increasing because it is a source of direct therapeutic agent with less adverse effects. The development in the science and technology improved the research on herbal medicinal plants. The efforts are also taken to improve the quality, efficiency and safety of the medicines. The present work aimed to develop the wholesome cream formulation which can protect and nourish the skin and also provide fast systemic healing acting through systemically. The herbal product intends to contain manjistha, guduchi, neem, moringa oil and aloe vera. The cream is anticipated to exhibit anti-inflammatory, anti-bacterial, nourishing effect on skin along with great anti-oxidant property.
Mathematical Model of Blood Flow through Capillaries to Study Transport of Nanoparticles Using Power Law Fluid Model
Authors: Basu B. Mallik , D.N Garain
Published: November 2022

A model of blood capillary flow that is axially symmetric with a peripheral layer and wall slip is provided mathematically in this study. Power law fluid was employed in the core area of suspension of all erythrocytes whereas Newtonian fluid was used in the periphery plasma layer to analyse longitudinal transport of nanoparticles within blood vessels. The capillary walls are impenetrable to nanoparticles in our study, and they are not absorbent. The formulas for the velocity profile, flow rate, mean velocity, and solute concentration were produced, and the findings were discussed using graphs.
A comprehensive indoor hygiene concept for infection prevention and control within built environments
Authors: Salonen Noora , Mäkinen Riika , Ahonen Merja , Mäkitalo Tiina , Pelto-Huikko Aino , Latva Martti
Published: November 2022

The COVID-19 pandemic has shown that actions related to infection prevention and control (IPC) need to be made more efficient, especially in indoor public spaces. Many standalone technologies and solutions are available to increase the hygiene levels of indoor environments. However, it is not clear how these technologies and solutions can be combined and adapted to building processes such that they cover the entire indoor environment and life cycle of a building—from its design to its use and maintenance. The construction industry faces challenges in this regard because many actors are involved, and interactions at multiple levels can hinder the implementation of innovations. Therefore, the aim of this article is to establish a framework for IPC within built environments by introducing a new indoor hygiene concept (IHC). It provides a tool for implementing necessary IPC actions during a building’s life cycle to construct or renovate hygienic indoor environments. The IHC is based on the idea that all the elements of an indoor environment need to be considered to create a hygienic building. In addition, hygiene objectives need to be set at an early stage of the construction process and monitored throughout all the phases of a building’s life cycle. This comprehensive approach enables designers, engineers, and other actors involved in different stages of a building’s life cycle to see their roles in the IPC of shared public spaces. Adopting this approach can result in fewer infection transmissions via indoor environments and, in turn, cost benefits for society.
Tamoxifen resistance-related ceRNA network for breast cancer
Authors: Qiao Zipeng , Xing Yu , Zhang Qingquan , Tang Yongjun , Feng Ruifa , Pang Weiyi
Published: November 2022

Background: Tamoxifen (TMX) is one of the most widely used drugs to treat breast cancer (BC). However, acquired drug resistance is still a major obstacle to its application, rendering it crucial to explore the mechanisms of TMX resistance in BC. This aims of this study were to identify the mechanisms of TMX resistance and construct ceRNA regulatory networks in breast cancer.

Methods: GEO2R was used to screen for differentially expressed mRNAs (DEmRNAs) leading to drug resistance in BC cells. MiRTarbase and miRNet were used to predict miRNAs and lncRNAs upstream, and the competing endogenous RNA (ceRNA) regulatory network of BC cell resistance was constructed by starBase. We used the Kaplan–Meier plotter and Gene Expression Profiling Interactive Analysis (GEPIA) to analyze the expression and prognostic differences of genes in the ceRNA network with core axis, and qRT-PCR was used to further verify the above conclusions.

Results: We found that 21 DEmRNAs were upregulated and 43 DEmRNA downregulated in drug-resistant BC cells. DEmRNAs were noticeably enriched in pathways relevant to cancer. We then constructed a protein-protein interaction (PPI) network based on the STRING database and defined 10 top-ranked hub genes among the upregulated and downregulated DEmRNAs. The 20 DEmRNAs were predicted to obtain 113 upstream miRNAs and 501 lncRNAs. Among them, 7 mRNAs, 22 lncRNAs, and 11 miRNAs were used to structure the ceRNA regulatory network of drug resistance in BC cells. 4 mRNAs, 4 lncRNAs, and 3 miRNAs were detected by GEPIA and the Kaplan–Meier plotter to be significantly associated with BC expression and prognosis. The differential expression of the genes in BC cells was confirmed by qRT-PCR.

Conclusion: The ceRNA regulatory network of TMX-resistant BC was successfully constructed and confirmed. This will provide an important resource for finding therapeutic targets for TMX resistance, where the discovery of candidate conventional mechanisms can aid clinical decision-making. In addition, this resource will help discover the mechanisms behind this type of resistance.
Biochemical and in silico inhibition of bovine and human carbonic anhydrase-II by 1H-1,2,3-triazole analogs
Authors: Khan Majid , Avula Satya Kumar , Halim Sobia Ahsan , Waqas Muhammad , Asmari Mufarreh , Khan Ajmal , Al-Harrasi Ahmed
Published: November 2022

A series of 1H-1,2,3-triazole analogs (7a–7d and 9a–9s) were synthesized via “click” chemistry and evaluated for in vitro carbonic anhydrase-II (bovine and human) inhibitory activity. The synthesis of intermediates, 7a and 7c, was achieved by using (S)-(-)ethyl lactate as a starting material. These compounds (7a and 7c) underwent Suzuki–Miyaura cross-coupling reaction with different arylboronic acids in 1,4-dioxane, reflux at 90–120°C for 8 h using Pd(PPh3)4 as a catalyst (5 mol%), and K2CO3 (3.0 equiv)/K2PO4 (3.0 equiv) as a base to produce target 1H-1,2,3-triazole molecules (9a–9s) for a good yield of 67–86%. All the synthesized compounds were characterized through NMR spectroscopic techniques. Furthermore, all those compounds have shown significant inhibitory potential for both sources of carbonic anhydrase-II (CA-II). In the case of bCA-II, compounds 9i, 7d, 9h, 9o, 9g, and 9e showed potent activity with IC50 values in the range of 11.1–17.8 µM. Whereas for hCA-II, compounds 9i, 9c, 9o, and 9j showed great potential with IC50 values in the range of 10.9–18.5 µM. The preliminary structure–activity relationship indicates that the presence of the 1H-1,2,3-triazole moiety in those synthesized 1H-1,2,3-triazole analogs (7a–7d and 9a–9s) significantly contributes to the overall activity. However, several substitutions on this scaffold affect the activity to several folds. The selectivity index showed that compounds 9c, 9k, and 9p are selective inhibitors of hCA-II. Kinetics studies showed that these compounds inhibited both enzymes (bCA-II and hCA-II) in a competitive manner. Molecular docking indicates that all the active compounds fit well in the active site of CA-II. This study has explored the role of 1H-1,2,3-triazole-containing compounds in the inhibition of CA-II to combat CA-II-related disorders.