bluuebunny/crossref_metadata_2025 huggingface dataset:
Spousal body weight concordance and the impact of spouse overweight on death risk: data form a 27-year cohort prospective study
Authors: Dolgalev I. V. , Ivanova A. Yu. , Karpov R. S. , Ovcharova P. A.
Published: June 2022

Aim. To study the interdependence of spousal body mass and influence of spouse overweight on the death risk according to the 27-year cohort prospective study.

Material and methods. We examined a random household sample (n=1546; married couples, 427). Overweight frequency among spouses was studied on the first stage of the study (1988-1991). In 2002-2005 (stage II), the examination was repeated and overweight dynamics were studied. In 2015 (stage III), we analyze mortality rates and significance of overweight and spousal overweight for the mortality risk formation. Overweight was detected in people with body mass index ≥25 kg/m2. Two hundred deaths were recorded during 27-year follow-up. Vital status was established for 97% of observed persons.

Results. Overweight was detected in 61,1% of men who lived with overweight wife and in 45% of men whose wife had normal body mass (p<0,01). Overweight was diagnosed more often in women whose husband also had overweight comparing with women who lived with normal weight husband (76,2% vs 61,7%; p<0,001). The risk of overweight formation among individuals whose spouse’s body mass increased from norm to overweight was in 3,04 times higher than in persons whose spouse had a stable normal body mass and in 2,2 times higher than in participants whose spouse had overweight on study stages I and II. Relative risk of mortality in men who lived with overweight wife was 2,07.

Conclusion. 1) We found the body mass concordance in spouses. 2) The average body mass index in men and women who lived with overweight spouse is higher than in men and women whose spouse had a normal body mass. 3) Interdependence of spousal body mass was revealed in dynamics. 4) Spousal overweight is an independent predictor of premature mortality in men.
Prevalence of carbohydrate metabolism disorders and association with cardiovascular diseases in a large Siberian region
Authors: Shabalin V. V. , Grinshtein Yu. I. , Ruf R. R. , Filonenko I. V. , Shalnova S. A. , Drapkina O. M.
Published: June 2022

Aim. To study the prevalence of carbohydrate metabolism disorders in a repre - sentative sample of the working-age population of the Krasnoyarsk Krai aged 25-64 years and to identify the association of these disorders with cardiovascular pathology.

Material and methods. A random representative sample within the all-Russian epidemiological study ESSE-RF included 1603 residents of the Krasnoyarsk Krai aged 25 to 64 years. The gradation of carbohydrate metabolism disorders was carried out on the basis of fasting plasma glucose level in accordance with the criteria of the American Diabetes Association (ADA). Hypertension (HTN) was defined as office BP ≥140/90 mm Hg or an indication of previous use of antihypertensive drugs. The presence of myocardial infarction (MI), stroke, coronary artery disease (CAD) was detected by anamnesis collection. Statistical processing was carried out using IBM SPSS v 22 and Microsoft Excel 2021 programs. When comparing differences by sex, age, level of education, and type of residence, differences was assessed by chi-squared test and considered significant at p≤0,05.

Results. In total representative sample of Krasnoyarsk Krai population, 3,6% of participants indicated prior diabetes, while its prevalence naturally increased with age. The detection rate of fasting glucose of 5,6-6,9 mmol/l among individuals without prior diabetes (impaired fasting glycemia (IFG), as one of the criteria for prediabetes, according to ADA guidelines) was 22,5% of the general population. Fasting hyperglycemia (HG) ≥7,0 mmol/l without prior diabetes was registered in 3,8%. This figure can be roughly considered as the proportion of people with newly diagnosed diabetes. IFG and HG were significantly more common among men, as well as among those with primary and secondary education compared with higher education. In rural residents, all types of carbohydrate metabolism disorders were more common than in urban ones. Compared with the normoglycemic group, the presence of prior diabetes, IFG and GH was associated with a significantly higher prevalence of hypertension, CAD and stroke.

Conclusion. The prevalence of IFG, fasting HG ≥7,0 mmol/l and diagnosed diabetes in a representative sample of the Krasnoyarsk Krai aged 25-64 years exceeds the national average, although it is consistent with the data of a number of other Siberian regions. The prevalence of both carbohydrate metabolism disorders in general and the percentage of possible undiagnosed diabetes increases with age. At the same time, there are more such individuals among those with primary and secondary education, as well as among rural residents. The approximate proportion of undiagnosed diabetes in the study population reaches 50%. Timely detection of carbohydrate metabolism disorders can contribute to the earlier implementation of active preventive measures and reduce the risk of cardiovascular events.
Behavioral and social risk factors for metabolically unhealthy obesity: data form a 12-year prospective study in the Russian population
Authors: Vinter D. A. , Mustafina S. V. , Rymar O. D. , Avdeeva E. M. , Shcherbakova L. V. , Malyutina S. K.
Published: June 2022

Aim. To study the contribution of behavioral and social risk factors to the development of metabolically unhealthy obesity (MUO) according to a prospective study in the Russian population.

Material and methods. From the HAPPIE project, 3197 people aged 45-69 years with a body mass index ≥30 kg/m2 were selected, who had all the necessary parameters for obesity phenotype determination. The prospective analysis included the first (2003-2005) and third screenings (2015-2017). A subsample was formed (n=1275; 276 men — 22%, 999 women — 78%). The mean follow-up period was 12,4 years. IDF criteria (2005) were taken for analysis.

Results. Men with a metabolically healthy obesity (MHO) phenotype most often have a secondary and higher education, while women with MHO — vocational and secondary education. In women, secondary education was most often noted. Among persons with obesity, both men and women are more often not single, while having MUO as follows: 56,8% and 34,2%, respectively. Men and women have a low-intensity activity, regardless of the obesity phenotype. The prevalence of smoking in the present time does not differ in the MHO and MUO groups. Metabolically healthy women consume more alcohol than those with MUO. In men with sedentary lifestyle and fasting hyperglycemia, the risk of MUO over a 12-year follow-up period was significantly higher. In women, the risk of conversion from MHO to MUO is increased when blood pressure (BP) is ≥130/85 mmHg.

Conclusion. In the Russian population, the risk of MUO in men increases with a level of physical activity <3 h/week and a blood glucose level ≥6,1 mmol/l; in women, only BP ≥130/85 mm Hg contributes to the development of MUO.
Results of a 7-year prospective follow-up in the Interepid study: factors influencing all-cause and cardiovascular mortality in rural residents of Russia and the Kyrgyz Republic
Authors: Myrzamatova A. O. , Kontsevaya A. V. , Polupanov A. G. , Altymysheva A. T. , Kashirin A. K. , Sirotko M. L. , Drapkina O. M.
Published: June 2022

Aim. To assess the 7-year survival rate and the association of risk factors (RFs) with all-cause and cardiovascular mortality among rural residents in Russia and the Kyrgyz Republic, as well as to analyze ethnic characteristics (according to the Interepid study).

Material and methods. This study was carried out within the Interepid international project, which included a cross-sectional epidemiological study of the prevalence of major noncommunicable diseases and their risk factors in 2011- 2012, and a prospective stage among rural residents of two countries (Russia, the Kyrgyz Republic). In 2019, the vital status of respondents was reassessed (7 years after the initial examination), and endpoints were collected, including all-cause and cardiovascular deaths.

Results. A significant similarity of rural residents of the analyzed regions in relation to the factors associated with mortality was revealed. Smoking in men, obesity in women, and hypertension in both sexes were associated with an increased death risk. Country differences were found only in relation to low physical activity and dietary habits. Ethnic developments in the population of the Kyrgyz Republic also concerned only the contribution of food habits.

Conclusion. The results obtained are important for planning, implementing and evaluating the effectiveness of public health promotion programs. It is also necessary to develop differentiated treatment and prevention measures in the Russian population and among the indigenous inhabitants of the Kyrgyz Republic, including taking into account the prevalence of CVD risk factors and their impact on life prognosis.
Analysis of factors associated with arterial stiffness in the general working-age population
Authors: Kaveshnikov V. S. , Trubacheva I. A. , Serebryakova V. N.
Published: June 2022

Aim. To examine associations of cardio-ankle vascular index (CAVI) with classical, behavioral and social risk factors (RFs) of cardiovascular disease (CVD) in adult population.

Material and methods. The study included 1365 people (women, 59%) from a representative sample aged 25-64 years (ESSE-RF), who underwent standard cardiology screening and volume sphygmography (VaSera-1500). All respondents signed an informed consent to participate in the study. The analysis included blocks of classical, social and behavioral risk factors for CVD. A linear model was used to identify associations. An error rate of <5% was considered significant.

Results. Age, sex, systolic blood pressure (SBP), triglycerides were associated with higher CAVI values, and body mass index (BMI) was associated with lower values, respectively. After 45 years, a direct association with heart rate (HR) became increasingly important, while after 50 years — with diabetes and the intake of beta-blockers, while the association between diabetes and CAVI was observed only among individuals not taking angiotensin-converting enzyme (ACE) inhibitors. A direct association was found with high-sensitivity C-reactive protein (hsCRP) in men, and an inverse association with diuretics in women, respectively. A sedentary work in combination with a history of bronchitis or with positive family history for CVD showed a direct relationship, while a sufficient physical activity (PA) showed an inverse relationship with the studied indicator, but only among people with belowaverage income.

Conclusion. According to the data obtained, in addition to age and sex, the following risk factors made a significant contribution to CAVI parameters in the examined population: BMI, SBP, triglycerides, diabetes, HR, intake of betablockers, diuretics, ACE inhibitors; hsCRP, PA. The unfavorable role of betablockers, high HR, diabetes, sedentary work, chronic lung pathology, hereditary burden, as well as the protective role of ACE inhibitors, diuretics and intense PA in relation to arterial stiffness in the working-age population has been shown. Additional studies are needed to determine the nature of a number of associations. The results obtained may contribute to the study of CAVI role in risk stratification and further development of methodological approaches to CVD prevention.
Current status of the problem of cardiovascular diseases in the Nizhny Novgorod region: possible ways to reduce mortality
Authors: Borovkova N. Yu. , Tokareva A. S. , Savitskaya N. N. , Krisanova K. I. , Kurashin V. K. , Odintsov G. A.
Published: June 2022

The article considers the urgent problem of combating cardiovascular diseases (CVDs) in the Nizhny Novgorod region, including the high prevalence of CVDs and the timely identification of risk factors. The changes in mortality from all and individual causes was analyzed. Attention was paid to the negative impact of the coronavirus disease 2019 (COVID-19) pandemic on the health of people suffering from noncommunicable diseases. We also described the necessity to improve healthcare efficiency for CVD patients by improving the complex of managerial and preventive measures.
CarotidSCORE.RU — risk stratification for complications after carotid endarterectomy
Authors: Kazantsev A. N. , Khasanova D. D. , Alpatskaya A. D. , Korotkikh A. V. , Dzhanelidze M. O. , Rusakova M. A. , Kharchilava E. U. , Sulimenko M. V. , Lutsenko V. A. , Sultanov R. V. , Alizada F. R. , Meleshin E. O. , Ginzburg E. R. , Gofman A. E. , Alekseeva E. O. , Lider R. Yu. , Pivovarov A. A. , Zakeryaev A. B. , Bagdavadze G. Sh. , Makoeva M. M. , Klimova A. I. , Zharova A. S. , Chernyavtsev I. A. , Abramov O. O. , Zakharova K. L. , Radzhabov I. M. , Karmokov I. A. , Kuklev A. P. , Solotenkova K. N. , Pachkoria M. G. , Sem’in I. S. , Kostenkov A. A. , Chernykh K. P.
Published: June 2022

Aim. To demonstrate the first Russian computer program (carotidscore.ru) for risk stratification of postoperative complications of carotid endarterectomy (CE).

Material and methods. The present study is based on the analysis of a multicenter Russian database including 25812 patients after CE operated on from January 1, 2010 to April 1, 2022. The following types of CE were implemented: conventional CE with patch angioplasty — 6814 patients; eversion CE — 18998 patients. Following postoperative complications were assessed during the study: death, stroke, myocardial infarction (MI), composite endpoint (death + stroke + MI).

Results. During inhospital postoperative period, 0,18% of participants died, while 0,14% had MI, 0,35% — stroke. The composite endpoint was recorded in 0,68%. For each factor present in patients, a predictive coefficient was estimated. The predictive coefficient was considered as a numerical parameter reflecting the strength of the effect of each factor on the development of postoperative complications. Based on this equation, predictive coefficients were calculated for each factor present in patients in our study. The total contribution of these factors was reflected as a percentage and denoted the risk of postoperative complications with a minimum of 0% and a maximum of 100%. On the basis of obtained calculations, a CarotidSCORE program was created. Its graphical interface is based on the QT framework. It is possible not only to estimate the risk of a complication, but also to save all data about a patient in JSON format. The CarotidSCORE program contains 47 patient parameters, including clinical, demographic, anamnestic and angiographic characteristics. It makes it possible to choose one of the four CE types, which will provide an accurate stratification of the complication risk for each of them.

Conclusion. CarotidSCORE (carotidscore.ru) may determine the probability of postoperative complications in patients undergoing CE.
Optimization of intravascular volume determination in patients with acute decompensated heart failure
Authors: Zhirov I. V. , Nasonova S. N. , Syrkhaeva A. A. , Lapteva A. E. , Osmolovskaya Yu. F. , Reitblat O. M. , Prints Yu. Sh. , Shariya M. A. , Tereshchenko S. N.
Published: June 2022

Acute decompensated heart failure (ADHF) is based on multilevel pathological pathways, which include hemodynamic overload and venous stasis. Determination of the volemic status is one of the most important tasks in managing such patients. Despite the availability of modern diagnostic markers (physical examination, chest x-ray, and brain natriuretic peptide (BNP) assessment), they do not accurately assess the degree of fluid overload, and therefore there remains a need to find a new, accurate and simple technology for assessing pulmonary congestion. The urgency of this problem has led to the development of a novel non-invasive remote dielectric sensing (ReDS) technology, which is a quantitative method for measuring the total volume of lung fluid by determining the tissue dielectric properties. The use of this technology makes it possible to quickly, non-invasively and quantitatively measure the fluid content in the lungs, makes it possible to optimize the treatment regimen and reduces the number of readmissions. This article presents the results of studies on the efficacy, safety and prospects for using a ReDS technology for the quantitative measurement of total lung fluid in patients with ADHF.
Do chemistry and rheology follow the same laboratory ageing trends in bitumen?
Authors: Pipintakos Georgios , Lommaert Caitlin , Varveri Aikaterini , Van den bergh Wim
Published: June 2022

The ageing of bitumen has received great attention both from a chemical and rheological perspective due to its direct impact on asphalt performance. However, open questions with respect to the convergence of the synchronous ageing changes in rheology and chemistry of bitumen still exist. This paper addresses these alterations of chemistry and rheology and attempts to establish a link via fitting rheological equations fed by fundamental chemical information. To that end, three binders of different type were used in four different laboratory ageing states. A number of spectroscopic techniques and rheological testing were employed to derive corresponding chemical and rheological parameters. In parallel, various statistical methods (Bivariate analysis, Wilcoxon test, Factor analysis) assisted in identifying relationships among the chemo-rheological parameters and simplifying the number of variables. The results of this study demonstrate that chemistry and rheology are following similar changes when considering laboratory ageing following the fast-rate phase of a dual oxidation scheme and short-term lab ageing. Finally, this work manages to establish a linking framework for a number of newly-introduced rheological parameters. All in all, the results of this study might be particularly interesting for future interventions in the chemical composition of bitumen, considering its effect on performance.
Retrospective Cross Sectional MRI Study of Morphometry of Menisci of Knee Joint
Authors:   Associate Professor, Department of Radiodiagnosis, MVJ Medical College &Research Hospital, Hoskote, Bangalore, Karnataka, India., Sandhya H  , Sangeeta M  ,   Professor and Head, Department of Anatomy, MVJ Medical College &Research Hospital, Hoskote, Bangalore, Karnataka, India., Afroze M Khizer Hussain ,   Assistant Professor, Department of Anatomy, MVJ Medical College &Research Hospital, Hoskote, Bangalore, Karnataka, India., Varalakshmi KL  ,   Professor, Department of Anatomy, MVJ Medical College &Research Hospital, Hoskote, Bangalore, Karnataka, India.
Published: June 2022

Introduction: Meniscal tears are commonly encountered in clinical practice and cause significant musculoskeletal morbidity. Most of the data available on Morphometry of menisci in Indian population are through cadaveric studies and very few MRI studies are available to substantiate the available data. Aim of the study: To gather data on the Morphometry of menisci in South Indian population and compare it with the existing literature. Material and Method: 100 MRI images collected retrospectively were used to study menisci. Height and width of MM and LM were measured both in sagittal and coronal planes. Results: It was observed that in both sexes the height of the Anterior horn of Medial meniscus was significantly higher than that of Lateral meniscus. Width of the Anterior horn and body showed significantly higher values in Lateral meniscus whereas width of Posterior horn of Medial meniscus showed significantly higher values in both sexes. Height of Medial meniscus in all the segments was higher in males though the difference was significant only in anterior horn and Posterior horn segments. Height of Lateral meniscus was significantly higher in males in all the segments. Conclusion: Results of this study will add to the existing literature on the Morphometry of menisci and will serve as a database for patients undergoing meniscal allografts. KEY WORDS: Medial meniscus, Lateral meniscus, Meniscal tears, musculoskeletal morbidity.
Correlation of Anthropometric Measurements of Proximal Tibia with Its Length for Stature Estimation in Forensic Analysis
Authors:   Associate Professor, Department of Anatomy, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, BG Nagara, Nagamangala, Mandya District, Karnataka, India., Balakrishnan Yogi Anupkumar , S Vikram  ,   Professor, Department of Anatomy, Surabhi Institute of Medical Sciences, Mittapally Village, Siddipet Mandal, & District, Telangana, India., Ningaiah Ajay ,   Associate Professor, Department of Anatomy, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, BG Nagara, Nagamangala, Mandya District, Karnataka, India., Lokanathan Tejaswi H ,   Professor, Department of Anatomy, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, BG Naga.ra, Nagamangala, Mandya District, Karnataka, India.
Published: June 2022

Background: Estimation of stature is one of the commonly used methods in forensic analysis to establish identity of individuals. Estimation of stature from fragments of long bones is done by deriving linear regression equations. The objective of the present study was to derive a simple regression equation for estimating length of the tibia using the morphometry of proximal end of tibia. Materials and methods: In this descriptive study carried out in the department of anatomy of a medical college, anthropometric measurements of proximal end of 150 dry human tibiae were collected irrespective of the sex and side. The parameters measured included the mediolateral length of the proximal end, the anteroposterior length of the medial and lateral condyle of tibia, anteroposterior length of the intercondylar area, and the circumference of proximal end of tibia. The measurements were done using Vernier calliper and measuring tape. Length of the tibia was estimated by using simple regression analysis. Results: The following linear regression equations were derived. Length of tibia can be calculated by, 29.2749 + (1.1925 × Mediolateral length) ±1.1926, 27.6418 + (2.333 × Anteroposterior length of lateral condyle) ±1.132, 21.8342+(3.2614 ×Anteroposterior length of medial condyle) ±1.328, 33.542 +(0.8952 × Anteroposterior length of intercondylar region) ±1.474, 23.1902 +(0.76379 × Circumference of proximal end) ± 1.134 Conclusion: The study revealed that there is a positive correlation between the measurements of proximal end of tibia and its length. The equation derived would help in forensic analysis to estimate the stature of an individual. KEY WORDS: Humans, Tibia, Linear Models, Forensic Anthropology, Body Height.
Double Cystic Ducts With The Single Gallbladder
Authors:   Associate Professor, Department of Anatomy, Government Tiruvannamalai Medical College, Tiruvannamalai, Tamilnadu, India., K. Sangameswaran
Published: June 2022

Background: Cystic duct is forming one of the boundaries of triangle of cholecystectomy. The variations in cystic duct anatomy are of considerable importance during surgical excision of the gallbladder. A double cystic duct is very rare and poses a challenge for surgeons during cholecystectomy operation. If duplication of cystic ducts is present, it is associated with a double gallbladder 80% of the time. Presence of duplication of cystic duct associated with a single gallbladder is a extremely rare variant. Most of the times this variation is not picked up on routine preoperative investigations of patients planned for a laparoscopic cholecystectomy and often present as an unusual ‘surprise’ during surgery and creates a challenge to the surgeons. If they fail to identify this very rare variation they may create iatrogenic injury to these cystic ducts, which leads to bile leakage and other complications. Aim of the study: To find out the incidence of variations in the number of cystic duct in cadavers. Materials and Methods: Present study was done in 50 adult cadavers in the Department of Anatomy, Government Tiruvannamalai medical college, Tamil nadu. Meticulous dissection was done in the hepatobiliary system of these cadavers, and the variations in the number of cystic duct were noted. Observations: Presence of double cystic ducts were seen in three cadavers. Conclusion: If an anomaly of the biliary ductal system is not identified before or during surgery, it may turn out to be a bile duct injury which leads to bile leak. Hence Surgeons should keep in mind about the possibility of this rare variant double cystic ducts with a single gallbladder while performing cholecystectomy surgery. KEY WORDS: Cystic duct, Gallbladder, Cholecystectomy.
Perception Of Medical Students Towards Online Teaching: A Questionnaire Study
Authors:   Associate Professor, Department of Anatomy, Adichunchanagiri Institute of Medical Sciences, B G NAGARA, Karnataka, India., Asharani S K  , Ningaiah Ajay ,   Associate Professor, Department of Anatomy, Adichunchanagiri Institute of Medical Sciences, B G NAGAR, Karnataka, India., Lokanathan Tejaswi Hiremarali ,   Associate Professor, Department of Anatomy, Adichunchanagiri Institute of Medical Sciences, B G NAGARA, Karnataka, India.
Published: June 2022

Background: The COVID -19, a novel coronavirus disease spreading across the globe, most countries including India have ordered the closure of all educational institutions which has put the academic calendar to a functional standstill. The pandemic forced many institutions to shift to online mode using Google meet, Zoom, Microsoft teams, etc. The teaching-learning methodologies have been revamped globally due to the covid outbreak that many schools and teachers around the world are coping with alternative ways for delivery of instructions. In spite of its multiple advantages, there are quite a few limitations faced by online teaching such as lack of student-teacher interaction, social isolation, network connectivity issues, etc. The deviation from traditional teaching to online teaching prompted this study to assess the perceptions of students towards online learning. Aim: The purpose of the study was to determine the perceptions of medical students towards online teaching during the lockdown Materials and Methods: After obtaining approval from the institutional ethical committee, the questionnaire-based study was conducted on 150 first-year medical students of Adichunchanagiri Institute of medical sciences, B G Nagara. The data obtained were statistically analyzed and tabulated. Results: Responses have clearly shown that students prefer the traditional method of teaching such as lecture, discussion, etc. over online classes due to multiple issues faced during online teaching. Conclusion: Online teaching is the most common method and the best platform to keep learners/students engaged and safe during the lockdown period for Covid-19. Despite being in the technological era, students are still more inclined towards face-to-face teaching rather than e-teaching due to various reasons. Administration and faculty members should take appropriate measures to improve e-teaching quality and help students in better learning. KEY WORDS: Perception, Students, online teaching.
Assessment of Lateral Ventricle Brain Indices In Indian Population Based On Age And Gender Using Computed Tomography
Authors:   Assistant Professor, Department of Radiodiagnosis, KMCH Institute of Health Sciences And Research, Coimbatore., Arasu P. Sabari , Kumar S. Arun ,   Professor, Department of Radiodiagnosis, KMCH Institute of Health Sciences And Research, Coimbatore., A. Pavithra  ,   Assistant professor, Department of Radiodiagnosis, KMCH Institute of Health Sciences And Research, Coimbatore., M. Vijaianand  ,   Professor, Department of Anatomy,  KMCH Institute of Health Sciences and Research,  Coimbatore, Tamilnadu, India.
Published: June 2022

Background: Bicaudate index, Bicaudate - temporal index and Huckman number were commonly used radiological indices to accurately evaluate intracranial ventricular volume. Established normal values for these indices were based on study done among western population. Reference values were not established for these indices in Indian population. Hence this study is undertaken to establish the new reference values for Bicaudate index, Bicaudate - temporal index and Huckman number, based on age and sex in Indian population. Methods: The retrospective study was done in Department of Radiology, Karpagam Faculty of Medical Sciences and Research, Coimbatore during the period between 1st June 2016 to 31st July 2016. One hundred subjects, aged between 5 to 90 years, with normal CT brain performed in Siemens SomatomScope multislice CT scanner were analyzed for this study and Bicaudate index, Bicaudate - temporal index, Huckman number were calculated. Results: Mean Bicaudate Index was 0.14 +/- 0.03. The mean Bicaudate - Temporal Index was 0.13 +/- 0.03. The mean Huckman number in male was 5.09 +/- 0.76 and in female was 4.70 +/- 0.57. Conclusion: The new reference values for Bicaudate index, Bicaudate - temporal index and Huckman number in Indian population based on age and gender was established in our study. KEY WORDS: Bicaudate index, Bicaudate - temporal index, Huckman number, Computed Tomography, Brain.
Intracranial Unruptured Right Internal Carotid Artery Aneurysm in A Cadaver: A Case Report
Authors:   Professor of Anatomy JSS Medical College JSS AHER, Mysore, Karnataka, India., Vidya CS  , Vidya GD  ,   Reader Department of oral pathology and Microbiology, JSS Dental College, JSS AHER, Mysore, Karnataka, India., Ravishankar MV  ,   Assistant Professor, Department of Anatomy, JSS Medical College, JSS AHER, Mysore, Karnataka, India.
Published: June 2022

Background: Dilatations of localised segments of the artery are called ‘aneurysms. Approximately 80% of aneurysms form in anterior circulation of circle of Willis. While 20% form in the posterior circulation of the brain. All aneurysms can cause symptoms because of compression of surrounding structures, thrombosis, rupture of emboli. Material and Methods: During routine dissection for I MBBS students in Department of Anatomy, JSS Medical College during intracranial dissection we encountered unruptured saccular aneurysm of intracranial internal carotid artery on right side Case report: Aneurysm of intracranial internal carotid artery was seen on right side of middle cranial fossa in a male cadaver. The aneurysm was close to right optic nerve and measured about 2.2 cm in width and 1.8 cm antero-posteriorly. No other intracranial pathology or anatomical variations were noted. Conclusion: The anatomical knowledge of aneurysm is important to Neurosurgeons, Endovascular surgeons, ENT surgeons and interventional Radiologists. KEYWORDS: Internal carotid artery, aneurysm, intracranial, subarachnoid haemorrhage.
Androgen Insensitivity Syndrome: A Case Report
Authors:   Professor and HOD Anatomy, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India., Shruthi B  N  , Venkatesh Vivikta ,   MBBS students, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India., Manoj D R Vishnu Sri ,   MBBS students, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India., Bharathi D  ,   Associate Professor of Anatomy, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India., Angadi  A V  ,   Professor & HOD, Department of Anatomy SSIMS &RC, Davangere, India., Saheb Shaik Hussain ,   Associate Professor, Department of Anatomy SSIMS &RC, Davangere, India.
Published: June 2022

Background: Androgen insensitivity syndrome refers to an inability of the body to respond properly to male sex hormones (androgens) produced during pregnancy. This occurs because of a change (mutation) in a gene involved in the production of the protein inside cells that receives the androgen hormone and instructs the cells in how to use it. This is a genetic disorder that makes XY foetuses insensitive (unresponsive) to androgens, they are born looking externally like normal girls and Internally, there is a short blind pouch vagina and no uterus, fallopian tube or ovaries. There are testes in the abdomen or in the inguinal canal. The CAIS is usually detected at puberty when a girl should but does not begin to menstruate. They are at high risk of osteoporosis so should take oestrogen replacement therapy. Case Report: PAIS results in micropenis with hypospadias and gynaecomastia. We report this rare case of 18yr old female patient with primary amenorrhea. Subsequent investigation including karyotyping revealed that the patient is phenotypically female but genotypically male with testes. Gonadectomy was done with proper counselling and patient was put on hormonal replacement replacement therapy. KEY WORDS: Androgen insensitivity, Primary amenorrhea, Pseudohermaphroditism.
La popularización del art déco de Curitiba en la Calle Barão do Rio Branco y sus alrededores
Authors: Tirello Regina Andrade , Aquino Emanuel Gonçalves
Published: June 2022

Los temas de debate sobre la cultura de conservación de los bienes inmuebles, asegurados a nivel internacional en la segunda mitad del siglo XX, cuando se amplían el campo y los objetos de preservación exponencialmente, encuentran creciente interés en examinar temas aún abiertos del patrimonio cultural constituidos por la denominada “Construcción menor” que conforman nuestras ciudades. Conceptos como la “conservación integrada” vuelven al presente en la perspectiva esperada de salvaguardar y valorar los bienes culturales tangibles que, para más allá de las categorías estéticas de las obras monumentales, engendran un necesario valor documental sobre la tecnología, la cultura y la sociedad que los produjo. Aportando reflexiones sobre las valoraciones históricas que delimitaron el perímetro circunscrito por el “Plan de Revitalización del Sector Histórico de Curitiba” implementado en los años 70, y reconocido en el país como experiencia pionera y modelo de preservación urbana, este artículo expone parte de la investigación de maestría que se vuelca a la identificación, documentación y análisis de espacios del antiguo centro cívico de esta ciudad, que reúne expresivo conjunto arquitectónico compuesto por edificios comerciales y residenciales con orientación protomodernista/art déco. Dicho acervo, aunque corresponda a elementos testimoniales del proceso de modernización de Curitiba, a constituir y a legitimar su paisaje cultural, aún carece de inventario científico y documental para subvencionar proyectos de conservación material y reutilización adecuada para la sociedad contemporánea. Tomando como eje de estudio referencial la Calle Barão do Rio Branco (ex Calle de la Libertad) y su entorno, este texto también expone aspectos de la metodología de trabajo de levantamiento catastral adoptada y resultados parciales de los procedimientos de “prospección urbana”, considerada una fase de análisis imprescindible para la serialización de los objetos para estructurar procesos sistemáticos de inventario del patrimonio arquitectónico de Curitiba en la primera mitad del siglo XX.
Serum microRNAs as biomarkers for the diagnosis of papillary thyroid carcinoma: a meta-analysis
Authors: Chen Yuping , Dong Bingtian , Huang Lichun , Huang Huibin
Published: June 2022

Papillary thyroid carcinoma (PTC) is the most common form of thyroid cancer. Several studies have proposed serum microRNAs (miRNAs) as novel biomarkers for diagnosing PTC. In this study, we conducted a meta-analysis aiming to investigate the overall diagnostic accuracy of serum miRNAs in PTC detection. Three online databases including PubMed, EMBASE and Cochrane Library were searched up to 1 May 2021. We systematically reviewed studies evaluating the value of serum miRNAs in diagnosing PTC, and then summarized the area under receiver operating characteristics curve (AUROC), sensitivity, specificity, and diagnostic odds ratio to assess the accuracy of serum miRNAs for the discrimination between patients with PTC and patients with benign thyroid nodules and healthy controls. We included 32 studies from 6 articles. Overall, there were 463 PTC patients, 334 patients with benign thyroid nodules, and 104 healthy controls. The results showed that the summary sensitivity and specificity were 76% (95% confidence interval [CI]: 68%‒83%) and 86% (95% CI: 80%‒91%), respectively, and that the summary AUROC was 0.89 (95% CI: 0.86‒0.91), when serum miRNAs were used for discriminating between PTC patients and those with benign nodules. On the other hand, the summary sensitivity and specificity of serum miRNAs for discriminating between PTC patients and healthy controls were 82% (95% CI: 77%‒86%) and 84% (95% CI: 76%‒90%), respectively, and the summary AUROC was 0.89 (95% CI: 0.86‒0.92). We found that serum miRNAs have good diagnostic performance for the discrimination between patients with PTC and patients with benign nodules and healthy controls, and thus have considerable potential as novel minimally invasive tools for detecting PTC.
Evaluation of clinical efficacy and safety of Bibrocathol 2% eye ointment in the treatment of Chronic Blepharoconjunctivitis
Authors: Elena Yani , Sergey Astakhov , Vladimir Brzheskiy , Evgeniy Egorov , Alexey Seleznev , Dorothea Groß , Heidi Opitz
Published: June 2022

Purpose: To assess the efficacy and safety of bibrocathol 2% eye ointment in patients with chronic blepharoconjunctivitis. Materials and methods: This was a multi-center, randomized, double-masked, placebo-controlled, parallel-group, phase III study. Patients with chronic blepharoconjunctivitis were randomized to apply either bibrocathol 2% (n = 100) or placebo (n = 100) three times a day for 14 days. The primary efficacy endpoint was the change from baseline to Day 15(+1 day) in the total score of signs summarizing the investigators’ assessment of the severity of lid oedema, lid erythema, debris, hyperemia, and pouting of Meibomian glands based on slit-lamp examination (modified Intention-to-treat (mITT) set). Safety endpoints included visual acuity, intraocular pressure, and adverse events. Investigators and patients performed an overall assessment of treatment tolerability. Results: On Day 15(+1 day) the least square (LS) mean change from baseline in the total sum score of signs was -8.62 (95% CI: -9.16; -8.08) in the bibrocathol group and -6.00 (95%CI: -6.54; -5.45) in the placebo group. The LS means the difference between treatment groups was statistically significant in favor of bibrocathol (-2.63 [95% CI: -3.36, -1.89], p < 0.001). Bibrocathol was statistically significantly superior to placebo in reduction of the individual ocular signs scores and the patient’s-assessed ocular discomfort severity (p < 0.001). No safety issues were observed concerning visual acuity, intraocular pressure, and the occurrence of adverse events. Conclusions: The study showed superior efficacy of two weeks of treatment with bibrocathol versus placebo in reducing signs and symptoms of chronic blepharoconjunctivitis. Treatment with bibrocathol 2% eye ointment was safe and well-tolerated.
NONLINEAR FINITE ELEMENT ANALYSIS OF MECHANICALLY ANCHORED REINFORCED STEEL I BEAMS
Authors: QARIZADA Abdul Majeed , SÜMER Yusuf
Published: June 2022

Aim: Steel structural elements can lose their strength in vehicle crashes, fire, fatigue, decay, humidity, etc. Consequently, their load-bearing capacities reduce considerably. A widely used strengthening method for steel beams is fiber-reinforced polymer strips or plates. One of the most important problems for this practice is sudden end-strip debonding due to the high normal and shear stress concentration. In this study, the structural behavior of deformed steel I-beams strengthened by carbon composites under bending was studied numerically. Using a commercial nonlinear finite element program (ABAQUS), a finite element model verified with the formerly executed experimental study was presented. To examine the effect of Mechanical Anchorage on large samples, a parametric study was carried out with the verified finite element model. In the parametric study, mainly three parameters were considered. Flange slenderness ratio (Bf/tf), web slenderness ratio (H/tw), and length to cross-sectional depth ratio (L/bf). Results derived from the nonlinear analysis revealed that the employment of the bolt anchorage increases the load capacity of the deformed elements and sustains the elements to resist more loads. However, the behavior and strengthening capacity of this practice is accordingly dependent on the flange slenderness ratio and web slenderness ratio of the proposed beam. Obtained results also indicate that the efficiency of mechanical anchorage in short-span beams is higher compared to the long-span beams.
DETERMINATION OF CONSTRUCTION PROJECT DURATION WITH ARTIFICIAL INTELLIGENCE
Authors: DOBRUCALI Esra , DEMİR İsmail Hakkı
Published: June 2022

Aim: With Industry 4.0, the period of digitalization has begun in the construction industry, as in many other industries. The use of artificial intelligence techniques or algorithms instead of traditional methods to solve the problems experienced in construction projects and increase the risk of the project has increased in recent years. These studies have shown that artificial intelligence techniques or algorithms give successful results in solving problems in construction projects. This study investigates the applications of artificial intelligence techniques on construction project duration and demonstrates the use of the Gene Expression Programming method in estimating construction project duration. Method: In this study, analyzes were made with Gene Expression Programming (GEP) technique to estimate the project duration by using the variables of the number of floors, floor area and total construction area of 71 construction projects (60 training and 11 test data) built between 2011-2016. Results: The determination coefficient (R2) for this study was calculated as 0.78 for the training set and as 0.72 for the testing set. Conclusion: In this study, it has been seen that the ability of the created algorithm to estimate the construction time with limited data provides partially acceptable performance.
EXAMINATION OF THE CAREER PLANS OF STUDENTS FACULTY OF SPORTS SCIENCES
Authors: KANTAR Ayşe Nilay , DONUK Bilge
Published: June 2022

Aim: The aim of this study is to investigate the career plans of the students of the Faculty of Sports Sciences and their attitudes towards the sports sector. Method: The sample of the study consists of the students of the Faculty of Sports Sciences studying in Istanbul. In the research, there is a personal information form that includes the participants' gender, age, department, willingness to choose the department, having relatives in the sector, the field they want to work, the reasons for choosing the department, and where they see themselves in the next 5 and 15 years. In addition, the scale containing the Plan and Anxiety for the Future and their attitudes towards the Sports Sector, which Dinçer, Akova and Kaya (2013) applied in their studies, was used. Results: According to the results; Although there is no significant difference between the participants' plans and concerns about the future according to the levels they see themselves in the future, a statistically significant difference was found in their attitudes towards the sports sector. In addition, when looking at the situation of having relatives in the sports sector; according to the test results; A significant difference was found between the future plans and concerns of the participants who are close to the sector. Conclusion: When we look at the reasons for choosing a department, according to the test results; A significant difference was found between the participants' plans and concerns about the future and their attitudes towards the sports sector.
INVESTIGATION OF FUTURE TIME PERCEPTIONS OF ADOLESCENT ATHLETES IN TERMS OF SOME VARIABLES
Authors: GÜMÜŞDAĞ Hayrettin , BASTIK Canan , AYDOĞAN Mehmet
Published: June 2022

Aim: The aim of this study “is to examine the perception of future time of adolescent athletes in terms of some variables such as age, gender, type of sport, breadth sub-dimension. Method: Participation of 13–18-year-old athlete adolescents in the adolescence period, which was chosen randomly, was provided on a voluntary basis. Participants in the survey in order to determine the future time perception scores Husman and Shell (1996) was developed by, Avcı and Erden (2009) adapted to Turkish, validity and reliability study were used to scale. In order to determine the distribution of socio-demographic information of the participants in the study; Kruskal Wallis and Mann-Whitney U tests were used to determine descriptive statistics and significant differences since they did not show a normal distribution. “p < 0.05”. Results: In the study, it was determined that there was a significant difference only in the width sub-dimensions in the variables of gender, age and sport type. Conclusions: it was determined that there was a significant difference at the p<0.05 level between age, sport type and the width sub-dimension of the perception of future time, while there was no significant difference in the other sub-dimensions. Considering that insufficient studies have been conducted on the perception of future time of adolescent athletes, it is important that coaches do not focus only on the physical performance of athletes, but also do studies that will contribute to their development, taking into account their psychological needs.”
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Authors: not provided DtieSmuh
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Authors: not provided contact.microbialtec
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Authors: not provided ruzald
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