bluuebunny/crossref_metadata_2025 huggingface dataset:
Painful radial nerve neuropathy with focal hourglass-like nerve constriction as a variant of distal neuralgic amyotrophy
Authors: Druzhinina E. S. , Druzhinin D. S. , Rogovskaya Yu. V. , Karapetyan A. S. , Vorobeva S. A. , Zavadenko N. N.
Published: February 2025

Neuralgic amyotrophy (NA, Parsonage-Turner syndrome) is an autoimmune multifocal painful neuropathy that has a classic pattern of brachial plexus involvement in most patients. Cases in which motor and sensory deficits occur below the elbow joint are classified as a separate form – distal NA. In contrast to the classic pattern of NA, patients with distal NA recover less well and require surgical treatment.

Objective: to describe the clinical and instrumental characteristics of patients with focal hourglass-like nerve constriction (FHNC) of the radial nerve.

Material and methods. The clinical, electrophysiological and neuroimaging data of 24 patients with painful radial nerve neuropathy (5 women and 19 men, mean age 41.9±15.5 years) were analyzed. The average time from onset of pain to diagnosis was 10.8 months (median 5 months; minimum 4 days, maximum 5 years and 8 months). Glucocorticoids (GC) were taken by 8 patients (33%). Nine patients underwent surgery. The control group consisted of 60 individuals matched for age and gender.

Results. All patients complained of neuropathic pain in the affected upper extremity with an average intensity of 9.4 (median 9.5) on the visual analogue scale (VAS). The duration of the pain syndrome was on average 13.4 days (median 12.5 days). According to electromyographic data, all patients showed changes in the muscles of the affected side in the form of chronic denervation. MRI of the nerve trunks in 12 patients, revealed no changes on the affected side in 5 patients (41.6 %). Edema of the nerve trunks was found in 5 patients (41.6%). Muscle atrophy was found in one patient (8.3%) and one patient (8.3%) had FHNC. Comparison of the ultrasound data of the cross-sectional area (CSA) of the affected and unaffected sides showed a significant enlargement of the radial nerve on the affected side (p=0.027); no statistically significant differences were found when comparing the affected and unaffected sides with the control group. FHNC in the radial nerve was found in 19 patients, with both sides affected in two cases. Four patients recovered completely, 3 of them (75 %) received GC and 2 (50 %) underwent surgery. Incomplete recovery was observed in 12 patients (50%). Eight patients (33%) did not recover, of whom only one received GC, while 4 (50%) underwent surgery. Of the patients who underwent surgery, 5 patients (55.6%) recovered completely or partially, 44% did not recover. The mean follow-up time was 10.2±2.9 months.

Conclusions. Radial nerve painful neuropathy is a variant of NA whose morphological manifestation is the phenomenon of FHNC detected by ultrasound in the peripheral nerves. The use of ultrasound facilitates the diagnosis of the disease, leading to an earlier diagnosis and consequently to a more favorable prognosis. Surgical treatment should be favored in cases of FHNC.
Salafis and Social Media: The Emergence of Islamic Populism in Indonesia
Authors: Muary Rholand , Susanti Neila , Atikah Puteri
Published: February 2025

The development of the Salafism movement in Indonesia is supported by the digitalization of their preaching, even though previously this group claimed to be Puritan, rejected modernization and was known to be strict in interpreting the Koran and hadith. This article explains how Salafi preaching is increasingly spreading on social media with an Islamic populism approach based on political economy. Salafists claim that the digitalization of their preaching can be accepted by society, especially young people in the upper middle class, as evidenced by the millions of people following their social media accounts. This research data was collected through in-depth interviews with Salafi figures and managers of their digital da'wah channels, namely Rasyaad TV in Medan and Surau TV in Padang, and observing content from Salafi's social media accounts. The findings of this research show that Islamic populism is developing and is characterized by the Salafist movement adapting to developments in the digital world. They promote their ideology through Instagram, YouTube, and satellite TV channels. Even though in the early days, their da'wah tended to be more conventional and limited to the Salafi Mahjab community, now it is open to anyone and anywhere. In packaging Salafi preaching content, this movement also adapts to local (Minangkabau) culture, so the local community can accept it. Salafis are also starting to show their support for the democratic system by participating in general elections even though they previously strongly rejected the democratic political system in Indonesia. These findings could have implications for the new Islamic populism movement with the struggle for digital space as the spearhead of da'wah to strengthen Salafi religious ideology as well as negotiate the political system that applies to Salafi congregations in Indonesia
Viability of Human Chondrocytes in an ex Vivo Model in Relation to Temperature and Cartilage Depth
Authors: Drobnič Matej , Marš T. , Alibegović A. , Bole V. , Balažic J. , Grubič Z. , Brecelj J.
Published: February 2025

Chondrocytes in human articular cartilage remain viable post-mortem. It has however not been established yet how the storage temperature affects their survival, which is essential information when post-mortem cartilage is used for toxicologic studies. Our aim was to construct a simple model of explanted knee cartilage and to test the influences of time and temperature on the viability of chondrocytes in the ex vivo conditions. Osteochondral cylinders were procured from the cadaveric femoral condyles. The cylinders were embedded in water-tight rubber tubes, which formed separate chondral and osteal compartments. Tubes were filled with normal saline, without additives, to keep chondrocytes under close-to-normal conditions. The samples were divided into two groups stored at 4 °C and 35 °C, respectively. Three samples of each of these two groups were analysed at the time of removal, and then three and nine days later. Images of Live-Dead staining were scanned by a confocal laser microscope. Count of viable chondrocytes in four regions, from surface to bone, was obtained using image analysis software. The regression model revealed that the number of viable chondrocytes decreased every day by 19% and that an increase in temperature by 1 °C decreased their viability by 5.8%. The temperature effect fell by 0.2 percentage points for every 100 µ µm from the surface to the bone. Herein we demonstrate that chondrocytes remain viable in the ex vivo model of human knee cartilage long enough to be able to serve as a model for toxicologic studies. Their viability is, however, significantly influenced by time and temperature.
In Vitro, Evaluation of Antioxidant Activity and Phytochemical Screening of Methanolic Extracts from Punica granatum Fruit Peels Collected in Northwestern Algeria.
Authors: Bourroubey Bachir , Bendjebbar Kaouter , Bettouati Abdelkader , Mennad Bendehiba
Published: February 2025

Natural antioxidants are becoming increasingly popular because of their importance in preventing and treating many diseases. This study investigates the antioxidant properties and chemical composition of methanolic extracts derived from the fruit peels of Punica granatum collected in Mostaganem, Algeria. Maceration was used for methanolic extraction of the dry peel powder, followed by both quantitative and qualitative chemical analyses. The antioxidant capacity of the extract was evaluated using three distinct assays: DPPH, ABTS, and FRAP. The results revealed a rich profile of bioactive compounds, including total phenolic content (187.13 ± 1.92 mg GAE/g dry extract), total flavonoid content (79.51 ± 0.83 mg QE/g dry extract), and total tannin content (48.09 ± 0.63 mg CE/g dry extract). Furthermore, the extract exhibited significant antioxidant activity, with IC50 values of 42.52 µg/mL for the DPPH assay, 47.49 µg/mL for ABTS, and 59.5 µg/mL for FRAP. Thus, very high antioxidant activity ratios were recorded, which were also statistically consistent with vitamin C and trolox at the highest concentration (200 μg/mL). These findings highlight the potential ofPunica granatum fruit peels as a valuable source of natural antioxidants, contributing to the prevention of oxidative stress-related diseases. Given their notable biological activity, pomegranate peels warrant careful consideration for incorporation into functional foods and dietary supplements, offering promising avenues for enhancing health.
Understanding premenstrual syndrome: experiences and influences among monastir university students
Authors: Toumi Dhekra , Ben Farhat Imen , Bergaoui Haifa , Ghaddab Imen , Hadj Mohamed Mariam , Aribi Ikram , Sallami Arige , Knaz Samar , Braiek Balsam , Mosbahi Ataa , Gharbi Nedra , Bouakez Sana , Baccouche Fadia , Zoukar Olfa , Hajji Ahmed , Faleh Raja
Published: February 2025

Menstrual health is increasingly recognized as a critical health issue by the World Health Organization, encompassing physical, psychological, and social dimensions. Approximately 1.8 billion women globally experience menstruation, with severe hormonal fluctuations leading to premenstrual syndrome (PMS) and its more severe form, premenstrual dysphoric disorder (PMDD), which significantly affects quality of life. This study investigates PMS symptoms among university students in Monastir (Tunisia) through a descriptive cross-sectional design involving 150 participants. Data was collected via a semi-structured questionnaire, assessing sociodemographic information and PMS symptoms using the validated A-PMS diagnostic tool. Results indicated that 100 % of participants experienced PMS, with 69.3 % reporting moderate to severe physical symptoms such as fatigue and pain, while 65.3 % noted significant psychological symptoms including anxiety and mood swings. Over half of the students reported mild impacts of PMS on relationships and academic performance, with 48 % experiencing absenteeism due to symptoms. Despite the prevalence of symptoms, the majority did not seek medical help. The findings highlight the critical need for educational institutions and healthcare professionals to address PMS and implement support strategies, thereby enhancing the well-being and academic success of young women. This research underscores the importance of raising awareness and developing effective interventions for menstrual health in this population.
Performance analysis of a PPM-OOK based hybrid modulation scheme for Satellite-to-Underwater FSO communication
Authors: Ahmed Syed Abrar , Rani M. S. Divya
Published: February 2025

This paper examines the performance of underwater wireless optical communication (UWOC) links using single-input and single-output (SISO) and selection combining (SC) receiver diversity techniques. To accurately model the effects of underwater turbulence on light propagation, the Malaga gamma (MG) distribution is employed for both weak and strong turbulence conditions. Analytical bit error rate (BER) expressions for on–off keying modulated UWOC links are derived for both SISO and SC receivers, utilizing the MG distribution’s power series representation. Monte Carlo simulations are conducted to validate the analytical BER results. The findings of this study provide valuable insights into the design and optimization of UWOC systems operating in various underwater environments.
Lokale Produktion: ein blinder Fleck?
Authors: Stoltenberg Lisa , Krenz Pascal , Saubke Dominik , Redlich Tobias
Published: February 2025

Um Nachhaltigkeitsziele zu erreichen und die Zukunft unseres Planeten sowie der Menschheit zu sichern, wird zunehmend angestrebt, lineare Wertschöpfungsmodelle durch kreisförmige zu ersetzen. Hierzu existieren verschiedene Strategien, die auch in den nationalen Nachhaltigkeitsplänen verankert sind. Allerdings verfolgen die meisten dieser Strategien das Ziel, Kreisförmigkeit zu erreichen, ohne dabei das Ausmaß dieser Kreise zu berücksichtigen. Ein darüber hinaus gehender Ansatz bestünde darin, die Kreisläufe gleichzeitig zu verkleinern, indem die Wertschöpfung möglichst nah am Ort des Bedarfs stattfindet. Dieser Beitrag setzt sich mit zwei verschiedenen Ansätzen zur Verkleinerung von Wertschöpfungskreisläufen auseinander und zeigt, wie lokale Produktionsnetzwerke sowie die Einbindung der Nutzer:innen in Wertschöpfungsprozesse zu einer Verkleinerung der Wertschöpfungskreisläufe beitragen können.
Optimization of Mango Plant Leaf Disease Classification Using Concatenation Method of MobileNetV2 and DenseNet201 CNN Architectures
Authors: Auni Ahmad Ramadhan , Sugiharti Endang
Published: February 2025

Purpose: Mango production can be severely impacted by diseases affecting mango plants. By leveraging artificial intelligence, the agricultural sector can automate the analysis of mango leaves to monitor plant health. The goal of this research is to improve the early detection of diseases in mango leaves to allow early treatment to minimize damage to the crops.
Methods: This study employs an approach of combining two pre-trained CNN architectures, namely MobileNetV2 and DenseNet201 through concatenation method. To enhance the model’s generalization ability, various image augmentation techniques were applied during the training phase.
Result: The model developed in this study achieved great performance in classifying mango leaf diseases with a testing accuracy of 99.25%. This result indicates the effectiveness of the concatenation method by outperforming the accuracy of either MobileNetV2 or DenseNet201 when implemented separately.
Novelty: This research introduces a novel strategy by concatenating two pre-trained CNN architectures for mango leaf disease classification, a method not previously explored in this context. The model developed from this study has the potential to serve as a tool for the early detection and treatment of mango leaf diseases.
Evaluation of thyroid ultrasound reports’ quality in the Community of Madrid, Spain
Authors: Valderrabano Pablo , Quiñones Silva Jhonatan Boris , Campos Mena Sandra , Familiar Casado Cristina , de Miguel Novoa María Paz , Sanabria Pérez María Concepción , Fernández Fernández Elisa , López Guerra Aurelio , Sambo Marcel , Martín Rojas-Marcos Patricia , Parra Ramírez Paola , Tasende Fernández Clara , Rodríguez Troyano María Jesús , Alcázar Lázaro Victoria , Lahera Vargas Marcos , Palacios García Nuria
Published: February 2025

Objective

To evaluate the current quality of thyroid ultrasound reports in the Community of Madrid.

Methods

Consecutive thyroid ultrasound reports from patients evaluated in the endocrine outpatient clinics of eight academic hospitals in the Community of Madrid were assessed for quality during 2021 and 2022. Descriptions of eight different features were evaluated: number and axes of dimensions, composition, echogenicity, margins, shape, calcifications and category of suspicion. Features were considered adequately reported if described for all nodules ≥1 cm. The number of correctly reported features was compared by year of data capture (2021 vs 2022), specialty of the informant (radiologist vs endocrinologist), and origin of the report (in-house vs outsourced center). The quality of reports for assessing the need for cytological evaluation and/or growth during follow-up was evaluated.

Results

A total of 1234 reports were included, 63% from 2021; 82% were issued by radiologists and 89% were issued in-house. Composition and echogenicity were the most frequently reported (79% and 72%, respectively). The rest of the features were appropriately described in less than half of the reports. Forty percent of the reports were good to select nodules for biopsy, 23% had sufficient data to assess growth during follow-up, and only 13% met both quality criteria. The overall quality of reports was worse in outsourced centers (median number of described features 2 vs 4, P < 0.001) and better when issued by endocrinologists (median number of described features 6 vs 3, P < 0.001).

Conclusions

Most thyroid ultrasound reports issued in the Community of Madrid provide insufficient data to make management decisions regarding thyroid nodules.
LA DESVIRTUADA JUDICIALIZACIÓN DE LA POLÍTICA: ESPECIAL ATENCIÓN AL TRIBUNAL CONSTITUCIONAL
Authors: Gálvez Galisteo Juan
Published: February 2025

En todo Estado de Derecho los poderes públicos deben encontrarse sometidos a límites y a controles. El recurso de inconstitucionalidad es una vía para encauzar el control jurisdiccional de la actividad del legislador, siendo una herramienta a la que tienen acceso habitualmente las minorías políticas. Por otra parte, existe también una dinámica asentada que consiste en residenciar los conflictos políticos a través de los tribunales. Aquí, se analizará la problemática de hacer un uso abusivo e ilegítimo de los mecanismos de control dentro de la judicialización de la política que estructura nuestros sistemas políticos, así como los riesgos para los sistemas de checks and balances y la calidad democrática implícitos en esta dinámica.
SUPERLIGA CONTRA UEFA: EL PARTIDO POR EL CONTROL DEL FÚTBOL EUROPEO
Authors: Müller Carlos
Published: February 2025

La FIFA y la UEFA llevan años siendo las asociaciones encargadas de la organización de competiciones de fútbol en Europa. El 18 de abril de 2021, doce grandes clubes europeos anunciaron la creación de una nueva competición, la Superliga Europea, obviando el requerimiento de solicitar autorización previa que recogen los Estatutos de FIFA y UEFA. La reacción sancionadora de estos organismos y la defensa de algunos fundadores han dado lugar a una disputa que ha llegado hasta el TJUE. La sentencia, de 21 de diciembre de 2023, declaró que la normativa de autorización previa de la UEFA (en la versión analizada) era contraria al Derecho de la Competencia. Esta sentencia es susceptible de cambiar la forma en la que el deporte se relaciona con el Derecho de la Competencia, estando en juego los principios más básicos del llamado «Modelo Europeo del Deporte». Este trabajo presenta un doble objetivo. Por un lado, busca presentar un análisis claro de la argumentación del Tribunal, en contraste con las Conclusiones del Abogado General de este caso. Por otro lado, pretende analizar el contexto en el que se enmarca esta sentencia y el impacto que puede llegar a tener sobre el «Modelo Europeo del Deporte», que parece ser un elemento socialmente deseable para las Instituciones de la Unión Europea.
LA UNIÓN EUROPEA COMO POTENCIA NORMATIVA EN UN MUNDO GLOBALIZADO: ¿SUEÑO O REALIDAD?
Authors: Neves Pérez Hugo
Published: February 2025

La Unión Europea (UE) es considerada, hoy en día, una potencia normativa. Ha logrado una posición destacada en el comercio internacional y se ha consolidado como uno de los principales mercados a nivel mundial, factores que le han permitido tener una influencia global en términos normativos, logrando que sus normas sean tomadas como modelos de referencia. El papel global de la UE ha sido analizado en base a sus componentes de poder y sus dimensiones de influencia, siendo considerada como una potencia blanda, civil o normativa, debido a su capacidad de influir a través de la persuasión y la atracción en vez de con la coerción. Sin embargo, la influencia de la UE como potencia normativa, en un mundo globalizado y cada vez más incierto, sigue siendo un tema de debate y controversia, ya que algunos cuestionan si realmente la UE tiene la capacidad de influir, de una manera efectiva, en el marco normativo global.  Por ello, el propósito de este escrito es dar luz a ese debate, con el objetivo de definir y reflejar el grado de influencia normativa que tiene la UE a nivel internacional.
Improvement of the accuracy of the reflector distance estimation in the Fresnel zone in the method of the time-domain signal synthesis based on the parametric spectral analysis
Authors: Drobakhin O.O. , Olevskyi O.V.
Published: February 2025

Current paper considers the problem of the longitudinal distance estimation on the ra-dar scan data with the help of the parametric spectral analysis methods. It is demonstratedthat the matrix pencil method and the Prony’s method are more capable at recovering thedistance difference between the scanned structures if the time of the calculation is compa-rable to the DFT method. The simulations for the paper are done with the help of themethod of auxiliary sources.
Numerical analysis of controlled motion of a quadcopter drone
Authors: Hart L.L. , Ruzhevych V.O. , Hart A.V.
Published: February 2025

The mathematical model of the drone-quadcopter motion control system with the justi-fication of the choice of control elements is considered. The penalty functional method forsolving the optimal control problem with three types of phase constraints is algorithmizedand implemented in software. Numerical schemes of this method based on the grid approx-imation of the corresponding control problem with the subsequent application of finite-dimensional constrained optimization methods are developed, recommendations for theirpractical use are provided.
Computer modeling of the non-stationary temperature distribution in bodies of spherical geometry
Authors: Karuna S.M. , Knysh L.I.
Published: February 2025

The processes of non-stationary heat exchange in bodies of spherical geometry are re-searched in this study. The mathematical model of thermal conductivity in a sphere and itsanalytical solution are presented and analyzed. The stability criterion for the analytical so-lution is determined under typical boundary and initial conditions. Numerical method forthe mathematical model with nonlinear and non-stationary boundary and initial conditionsis developed. The numerical method is based on functional programming using built-infunctions of the Maple software. The typical temperature distributions inside a sphere de-pending on time and radius were obtained. Developed approach significantly minimizestime of calculation for heat exchange problems in bodies of spherical geometry and showscapabilities of the system computer algebra Maple in terms of solving non-stationary non-linear problems of mathematical physics.
Using machine learning methods to optimize business processes in IT projects
Authors: Zolotko K.E. , Krasnoshapka D.V. , Stepanova N.I. , Siryk S.F.
Published: February 2025

This article explores the potential of machine learning (ML) methods to optimize busi-ness processes in IT projects, with a focus on improving management efficiency, minimiz-ing time and financial costs, and enhancing decision quality. The authors analyze the use ofML to address a range of tasks, including forecasting time costs and resource allocation,automating routine operations, task distribution, and performance monitoring. The ad-vantages of machine learning algorithms are demonstrated through examples such as de-fect detection, test automation, customer feedback analysis, and improving user interactionthrough recommendation systems. The article shows that the implementation of ML helpsreduce errors, increase the reliability of IT products, and enhance the customer experience,making machine learning an essential component of modern IT projects.
Az Ötfaktoros Jelentudatosság Kérdőív rövidített, 15 tételes verziójának pszichometriai elemzése magyar mintán
Authors: Rendes Réka , Horváth Diána Ágnes , Deák Anita
Published: February 2025

Elméleti háttér: A mindfulness (tudatos jelenlét, jelentudatosság) olyan kognitív és érzelmi szempontból összetett jelenség, amely magában foglalja a jelen pillanatra irányuló fenntartott figyelmet, vala-mint a tapasztalatok felé mutatott nyitott, kíváncsi és elfogadó attitűdöt. A mindfulness alapú terápiák rámutatnak arra, hogy a tudatos jelenlét nemcsak egy önmagán belül zajló folyamatot jelöl, hanem egyfajta képességként is definiálható, ennek értelmében pedig gyakorlással fejleszthető. Az egyik leggyakrabban alkalmazott mindfulness képességet vizsgáló mérőeszköz az Ötfaktoros Jelentudatosság Kérdőív (Five Factor Mindfulness Questionnaire, FFMQ). Az eredeti, 39 tételes FFMQ öt dimenzió –  Megfigyelés, Leírás, Tudatos cselekvés, Ítélkezésmentesség, Reakciómentesség – mentén ragadja meg a mindfulness jelenségét. Célkitűzés: A kérdőívnek rövidített változatai is születtek, amelyek közül jelen vizsgálat a legrövidebb, az eredeti kérdőív szerzők által leírt 15 tételes változatának (FFMQ-15) adaptációját tűzte ki célul hazai mintán. Módszerek: Az FFMQ-15 magyar nyelvű változatát 117 résztvevő töltötte ki egy kérdőívcsomag részeként. A kérdőívcsomag az FFMQ-15 mellett demográfiai kérdéseket, illetve a konvergens és diszkriminációs validitás mérésére alkalmazott kérdőíveket (Mentális Egészség Kontinuum Skála [MHC-SF], Depresszió, Szorongás és Stressz Skála [DASS-21], Big Five Kérdőív [BFI], Fehér Medve Gondolatelnyomási Kérdőív [WBSI], Érzelemszabályozási Nehézségek Skála [DERS], Kognitív Érzelem-Reguláció Kérdőív [CERQ], Torontói Alexitímia Skála [TAS-20]) tartalmazott. Eredmények: Az FFMQ-15 hierarchikus faktorstruktúrája (5 elsőrendű és 1 másodrendű faktor) konfirmatív faktorelemzéssel megerősítésre került (CFI = 0,976; TLI = 0,967; RMSEA = 0,047; SRMR = 0,084). Az FFMQ-15 konvergens és diszkriminációs érvényességét vizsgálva megállapítható, hogy a tudatos jelenlét képessége a várt irányú kapcsolatot mutatta a mentális egészség (MHC-SF), a depressziós, szorongásos és stressz tünetek (DASS-21), a tapasztalatokra való nyitottság és neuroticizmus (BFI), gondolatelnyomási tendenciák (WBSI) és érzelmi működés (DERS, TAS-20, CERQ) mutatóival. Követ- keztetések: Összességében kijelenthető, hogy az Ötfaktoros Jelentudatosság Kérdőív rövidített 15 tételes verziója alkalmas a mindfulness-képesség egyéni különbségeinek megragadására hazai mintán is.
Local Power in Old Babylonian Mesopotamia
Authors: Seri Andrea
Published: February 2025

This book focuses on certain local powers in Old Babylonian Mesopotamia (ca. 2000 – 1595 B.C.), namely the chief of the city (rabianum), the elders, the “city,” and the assembly. This is a novel approach to Old Babylonian history that allows us to understand the constituency, activities, and sphere of influence of local institutions of authority, and the way they coped with state officials and royal policies. Focusing on local powers changes the traditional manner of looking at the state. This is so because far from being a monolithic entity that unilaterally made decisions concerning people, water, land, and other resources, the state had to deal with local institutions that were not always willing to accept royal decisions passively. The state was often unable to penetrate deeply into traditional social and economic practices that were controlled by local leaders, as is most apparent in the conflict of jurisdiction related to land distribution. However, the state did surreptitiously co-opt local leaders into the royal domain. The methodology and conclusions of this case study of local authorities in Old Babylonian Mesopotamia will also be useful for those studying other ancient states and complex societies.
Performance and Cost Efficiency of Snowflake on AWS Cloud for Big Data Workloads
Authors:   Cyber Security Senior Data Analyst, Department of Cyber Security, Truist Financial, CA, USA, Kodi Divya
Published: February 2025

In the era of big data, organizations require robust, scalable, and cost-effective solutions to manage and
analyse vast datasets efficiently. Cloud-based data warehousing has emerged as a key technology in addressing these
challenges, providing flexible storage, high performance, and cost efficiency. Among the various cloud data
warehousing platforms, Snowflake has gained significant traction due to its unique architecture and seamless
scalability.
This paper provides an in-depth analysis of the performance and cost efficiency of Snowflake when deployed on
Amazon Web Services (AWS) for big data workloads. We examine the technical aspects of Snowflake’s architecture,
including its separation of storage and compute, and its impact on query performance and resource optimization.
Benchmark tests were conducted to evaluate query execution times, data loading speeds, and workload scalability
under varying conditions.
Additionally, we explore the financial implications of using Snowflake on AWS, comparing its pricing model with
traditional data warehousing solutions and alternative cloud-based platforms such as Amazon Redshift, Google
BigQuery, and Microsoft Azure Synapse Analytics. Cost-saving strategies, including auto-scaling and warehouse
suspensions, are discussed to optimize resource utilization and reduce expenditures.
Security and compliance are also considered, highlighting Snowflake’s encryption standards, role-based access
controls, and adherence to industry regulations like GDPR and HIPAA. The study further outlines emerging trends in
cloud data warehousing, including AI and machine learning integration, multi-cloud interoperability, and enhancements
in real-time analytics.
Our findings indicate that Snowflake’s architecture and pricing flexibility make it a compelling choice for organizations
dealing with large-scale data analytics. While its performance and efficiency are well-suited for dynamic workloads,
careful planning and optimization are essential to fully leverage its capabilities and control costs effectively. Future
advancements in AI-driven optimizations and multi-cloud capabilities are expected to enhance Snowflake’s appeal,
making it a sustainable solution for data-driven enterprises
Potential of Water Hyacinth (Eichhornia crassipes) as Compost and its Effect on Soil and Plant Properties: Review
Authors:   Master of Agriculture Candidate, Department of Food Security and Agricultural Development, Kyungpook National University, Daegu South Korea, Khan Shifadjzic
Published: February 2025

: Water hyacinth (Eichhornia crassipes), an invasive aquatic weed, poses significant environmental and
economic challenges due to its rapid proliferation in water bodies. However, its high biomass production and rich organic
content make it a promising raw material for composting. This study explores the potential of water hyacinth compost
(WHC) as an alternative organic fertilizer and its effects on soil properties and plant growth. The composting process
enhances nutrient availability, improving soil fertility by increasing organic matter, nitrogen, phosphorus, and microbial
activity. WHC has been found to enhance soil aeration, water-holding capacity, and cation exchange capacity (CEC),
leading to improved crop productivity. Additionally, it contributes to sustainable weed management by converting an
invasive species into a valuable agricultural input. However, challenges such as high moisture content, heavy metal
accumulation, and proper composting techniques must be addressed for effective utilization. The study highlights the
need for further research on optimizing water hyacinth composting methods and integrating it into sustainable farming
practices. By converting this noxious weed into a beneficial soil amendment, water hyacinth composting presents a dual
solution—environmental management and agricultural enhancement. The findings suggest that water Hyacinth Compost
can be a viable organic alternative to synthetic fertilizers, promoting eco-friendly and cost-effective farming practices.
The head and neck features of Gardner’s Syndrome: A case report and review of the literature
Authors: Black AI , Bunn BK , Motloba PD , Gwengu P
Published: February 2025

Gardner’s Syndrome represents an autosomal dominant variant of Familial Adenomatous Polyposis in which affected individuals have a 100% risk of developing colorectal carcinoma. The extra-intestinal manifestations in the head and neck region allow for the early recognition and diagnosis of this rare syndrome. The defining triad of features includes intestinal polyposis, dento-osseous anomalies and soft tissue lesions. A 20-year-old female patient presented with a main complaint of swelling involving the left side of her nose, at which time a panoramic radiograph was obtained.Radiographic findings showed multiple osteomas, odontomas, missing teeth as well as unerupted and impacted teeth, the features of which are highly suggestive of Gardner’s Syndrome. Early recognition of the extra-intestinal features of Gardner’s Syndrome warrants patient referral for further investigation including colonoscopy and genetic testing
The orthodontic treatment needs in children aged 12-15 years in a school in Khomas, Namibia: A cross-sectional study
Authors: Serebe  Catherine , Harris Angella , Kimmie-Dhansay Faheema
Published: February 2025

The aim of this study was to determine the orthodontic treatment needs of a population of 12-15 year old school children and to express it as percentages of those subjective and objective orthodontic treatment need over the whole  sample population. There has been a disagreement between normative and subjective need for orthodontic treatment. This is especially true in an African setting.The aim of this cross-sectional study was to determine the orthodontic treatment needs of a population of 12–15-year old children attending a school in Khomas, Namibia. The Modified Index of Orthodontic Treatment Need (IOTN), using the Dental Health Component (DHC) and the Aesthetic Component (AC), was used to determine the normative and subjective need for orthodontic treatment respectively
Resisting Erasure: A Critical Review
Authors: AlAshmar Mohamad
Published: February 2025

This book review examines The Untold Story of the Golan Heights, which highlights the Jawlani Druze experience under Israeli occupation. The book explores identity, resistance, and survival through a decolonial and interdisciplinary lens, challenging dominant narratives. It offers valuable insights into the region’s complex realities.
تتناول هذه المراجعة كتاب "القصة غير المروية عن هضبة الجولان"، والتي تسلط الضوء على تجربة دروز الجولان تحت الاحتلال الإسرائيلي. يستكشف الكتاب مواضيع الهوية والمقاومة والبقاء من خلال إطار متعدد التخصصات، متحديًا السرديات السائدة. الكتاب يطرح رؤى قيمة حول الحقائق المعقدة في المنطقة.
Study on the mechanism of Wnt/β-catenin pathway mediated by pterostilbene to reduce cerebral ischemia-reperfusion injury
Authors: Jin Yang , Fu Chunwang , Guo Ming , Yang Qiang
Published: February 2025

Cerebral ischemia-reperfusion injury (CIRI) is the primary cause of damage following ischemic stroke, with ferroptosis serving as a key pathophysiological factor in CIRI. Pterostilbene (PTE) has been shown to reduce cerebral ischemic injury, but whether its mechanism of action involves ferroptosis remains unclear. In this study, an in vitro model of mouse hippocampal neuron (HT22) cell injury and an in vivo mouse CIRI model were established. Treatments included PTE, the ferroptosis activator Erastin, and the Wnt signaling pathway inhibitor (Dkk-1). Cell damage was assessed using flow cytometry, MTT assay, lactate dehydrogenase (LDH) release assay, and Calcein-AM/PI staining. Oxidative stress and ferroptosis in cells and tissues were evaluated using biochemical kits and fluorescence staining. Additionally, histopathological staining was performed to assess brain tissue damage, while qRT-PCR and Western blot analyses were used to measure ferroptosis-related factors and Wnt/β-catenin pathway-related proteins in both cells and tissues. HT22 cells subjected to injury exhibited decreased viability and increased cell death (P < 0.05). Similarly, CIRI mice demonstrated pronounced cerebral infarction and neuronal damage. Ferroptosis, characterized by elevated levels of iron ions, lipid peroxides (ROS and MDA), and reduced antioxidant enzymes (GSH and GPX4), was significantly increased in both cells and tissues (P < 0.05). Correspondingly, ferroptosis-related protein levels were elevated (P < 0.05), while Wnt/β-catenin pathway-related protein levels were significantly decreased (P < 0.05). Treatment with Erastin and Dkk-1 exacerbated neuronal damage, intensified ferroptosis, and inhibited the Wnt/β-catenin pathway. Conversely, PTE treatment activated the Wnt/β-catenin pathway, reduced ferroptosis, and improved neuronal damage. Specifically, PTE upregulated the Wnt/β-catenin pathway, decreased peroxide accumulation, and antagonized ferroptosis, ultimately mitigating CIRI. These findings suggest that PTE protects against CIRI by modulating the Wnt/β-catenin pathway and alleviating ferroptosis-induced damage.
Instructions for installation and running code v2
Authors: Sandulache Vlad
Published: February 2025

This protocol details the use of codes for the analysis.
Preparation of pharmacological agents v2
Authors: Nelson Alexandra , Girasole Allison , Ryan Michael , Twedell Emily , Paz Rodrigo , zhuang xiaowen
Published: February 2025

This is a description of how we prepare different drugs for use in live animals (in vivo) or in brain slices (ex vivo).
Blinded IL-6 Measurement for Novel Biosensor Evaluation v1
Authors: I. Martinez-Banderas Aldo , Paul Hubert , Malki Anas , Petrich Wolfgang
Published: February 2025

In order to obtain an initial impression on the capabilities of novel biosensors, it is necessary to aim to separate the impact of the chemical part of the detection, such as the choice of antibodies in immunological testing, from the measurement technology part. It is therefore advisable to use data from measurements of common analytes under conditions as similar as possible. In this protocol, blinded pre-characterized samples at different concentrations provided by an evaluator are measured using the novel biosensor technology under investigation. In particular, samples are prepared in order to allow the evaluation of the accuracy of the determination of their concentration, of the sensitivity of the platform and of the linearity of the response and dynamic range. In turn, this protocol does not include the measurement of precision in terms of inter- and intra- assay variability nor accounts for day to day or operator variability.
Gender Rhetoric for Sale: Ferragni and the Platformization of the Female Body That Crushes Ideologies
Authors: Risi Elisabetta , Polesana Maria Angela
Published: February 2025

This article aims to make a contribution to the study of liberal feminism, social media, and influencer culture, especially in the Italian context. The feminism of Chiara Ferragni, Italian fashion influencer with over 29 million followers, is an interesting case study that questions the relations, as well as the interaction, between activism, gender, and influencer culture. Ferragni’s body simulacrum, exhibited through numerous social media advertising images, was displayed at Sanremo, a renowned Italian song festival, watched by 12 million people in 2023. At Sanremo, that body carried on the feminist battle through the wearing of manifesto luxury designer dresses together with the reading of a letter addressed to herself, a vector of a rhetorically powerful message that was, however, directed to the single woman rather than to women as a collectivity. This neoliberal discourse is emblematic of the instrumental use of gender issues for self-promotion, which often leads to the dilution of feminist meanings and the trivialization of social movements.
DISCRETIZED POISSON-EXPONENTIATED WEIBULL DISTRIBUTION AND ITS APPLICATIONS
Authors: George Alphonsa , George Dais
Published: February 2025

In this article, a discretized form of Poisson-exponentiated Weibull distribution namely, discrete Poisson exponentiated Weibull (DPEW) distribution is introduced and studied. The model parameters are estimated using the method of maximum likelihood and its accuracy is established through simulated data. The adequacy of the new distribution in modelling count datasets, in comparison to alternative distributions, is demonstrated with different real datasets of asymmetric nature. A bivariate form of discrete Poisson-exponentiated Weibull distribution is also developed by considering Farlie-Gumbel-Morgenstern copula.
PIPE LIKE SPACES AND THEIR -ALGEBRAS BY -THEORY
Authors: SUDO Takahiro
Published: February 2025

We study pipe like spaces and their -algebras by -theory.
Ocios líricos. La obra olvidada de Francisco Antonio de Castro (1670-1740)
Authors: Carabias Orgaz Miguel
Published: February 2025

Damos a conocer un cancionero, hasta ahora inédito, que se ha conservado en una sola copia de comienzos del siglo XVIII. Contiene obra lírica abundante y variada, pues compendia los principales temas y formas de la lírica barroca, y además anticipa algunos aspectos que décadas más tarde señalarán el tránsito hacia una nueva sensibilidad literaria. Su autor, Francisco Antonio de Castro, aunque había publicado algunas obras eruditas y religiosas, se despreocupó de sus composiciones juveniles, mucho más interesantes, las cuales en buena medida quedaron recogidas en este manuscrito.
Libelos en torno a María de Navas "la comedianta". Realidad social y situación profesional de un arte controvertido
Authors: Flórez Asensio María Asunción
Published: February 2025

La polémica sobre la licitud o legitimidad moral del teatro arreciará con gran virulencia a partir de 1682, tras la publicación de la Aprobación a la Verdadera Quinta Parte de Comedias de don Pedro Calderón de Fray Manuel de Guerra y Ribera. Este extenso documento, que excede con mucho al trámite ordinario de la aprobación eclesiástica preceptiva para la publicación de cualquier obra, defiende también la legitimidad del teatro y de los actores que lo representan. En relación con él aparecerán una serie de libelos anónimos cuya originalidad reside en que tienen como protagonista a una "comedianta": María de Navas, "primera dama de una Compañía de Corte" durante más de treinta años. Miembro relevante de un grupo social y profesional muy alejado de los modelos que la sociedad barroca trataba de imponer a las mujeres, la actriz aparece en ellos como viva encarnación de todos los males del teatro, que tanto preocupaban a sus detractores.
Private and Intellectual Conflicts and the Mysteries of the Empresas Políticas in the Unpublished Letters of Juan Antonio de Vera, Count of La Roca, to Diego Saavedra Fajardo (1634-1640)
Authors: Monostori Tibor
Published: February 2025

The unpublished correspondence between two renowned Golden Age writers and diplomats reinforces the view that intense political and intellectual networks and circles reigned in the diplomatic corps and the cultural milieu in the seventeenth century. Juan Antonio de Vera, Count of La Roca, and Diego Saavedra Fajardo, a diplomat from Murcia, needed each other as information hubs, intellectual control points and transmitters of cultural goods. They engaged in professional debates about the foreign policy of Madrid. La Roca repeatedly treated the diplomat with disdain and condescending superiority. A note on the Empresas Políticas casts a shadow on its first edition and highlights a puzzle.
La búsqueda del mecenazgo a través de la poesía sevillana impresa (1649-1682)
Authors: Collantes Sánchez Carlos M.
Published: February 2025

En este trabajo se reflexiona acerca de la función de la dedicatoria de los impresos poéticos sevillanos como un espacio paratextual utilizado en la búsqueda de mecenazgo. Para ello se analizan 54 obras poéticas, tanto pliegos de cordel como poemarios, impresas en Sevilla entre 1649 y 1682. Se describen las estrategias editoriales seguidas por los poetas para obtener el favor del mecenas a través de las letras de molde. Tras estudiar el paratexto de la dedicatoria desde la perspectiva literaria y material, se observa una tendencia a la pretensión de un mecenazgo vinculado a los poderes locales.
Identidad latinoamericana en la obra Estancia, op. 8 (1941) de Alberto Ginastera
Authors: Calvache David
Published: February 2025

This work analyzes the musical composition Estancia, op. 8 (1941) by Alberto Ginastera, taking into account its musical, literary, and social origins and influences. Its themes and artistic content highlight issues that, even though they emerged in the 19th century, continue to be relevant in Latin America today. It begins with the concepts of mestizaje and Latin American identity as a framework. Then, it provides a literary perspective on the context of the musical work's plot. Subsequently, a structural and stylistic analysis of Estancia is conducted, emphasizing what can be considered as musical mestizaje through the various voices found in its compositional language and how Ginastera brings them together. It concludes with a general interpretation of the music and its context, examining what can be considered common among the convergence of so many heterogeneous aspects in the work of the Argentine composer, what the concept of Latin American identity might be derived from the composition, and how some of the issues raised in the work are still relevant today.
La competencia digital docente post covid
Authors: Agurto Castillo César Martín , Martínez Gonzales Gloria , Agurto Romero César Alexander
Published: February 2025

The research carried out has allowed us to understand in depth the level of digital competence that teachers from various educational institutions have, facilitating the establishment of a north in terms of educational technological support. The methodology has been categorized as a quantitative approach and systematic review of bibliographic sources through the critical analysis of selected articles. A survey was conducted on a representative sample of teachers from different educational levels to assess their level of digital competence before and after the COVID-19 outbreak. Additionally, in-depth interviews were conducted with a subgroup of teachers to better understand the challenges and needs in terms of digital competence. The world of technology and digitalization has become essential in the academic space as a means to continue developing pedagogical tasks and innovation in the educational sector in this radical change caused by COVID19. It is advisable to carry out training to strengthen the technological capabilities of both university and regular basic education teachers because in the study carried out some deficiencies have been noted by the teaching staff in terms of a good consolidation of the digital world. Research reveals that many teachers have experienced difficulties adapting to new technologies and educational platforms during the pandemic.
Las TIC:
Authors: Gavilanez Maria de Lourdes , Uyaguari Darwin
Published: February 2025

The aim of the study is to analyze the role of ICT in processes of dialogue and interaction among peers in virtual environments in Middle School Education. The scope is analytical, with epistemological perspectives characteristic of the humanistic paradigm and qualitative research. Among the results, the following are highlighted: the effects of limited peer interaction on learning, the use of technologies as an educational resource, the teacher's role in planning and managing technologies and cooperative learning activities, the impact of virtual environments and digital tools on access to information and the development of processes of collective construction. Thus, it is concluded that ICT surpass the notion of a classroom resource by being a dialogical medium of learning that enhances interaction among peers, whose properties the teacher must manage to build valuable educational spaces and experiences.
El aprendizaje basado en el lugar y sus alcances en la educación actual
Authors: Bogoya Caviedes Giovanny Eduardo , Prado Delgado Víctor Manuel
Published: February 2025

This article presents a systematic literature review on Place-Based Learning (PBL). The documentary search was conducted using the PRISMA research method, examining articles published between 2000 and 2024 in the databases: Scopus, Scielo, Science Direct, Redalyc, and Dialnet. The search equations and Boolean operator used were: "aprendizaje basado en el lugar," "place based learning," "aprendizaje basado" AND "en el lugar." The review aimed to identify the state of research on PBL in Ibero-America during the 21st century. It analyzed its background, definition, fields of study, and analytical approaches. The results indicate that PBL is a recent field of study that connects learning with local environments. It is suggested to continue systematizing the category to enrich teaching practice and understand its impact in various contexts