bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on pilling performance of polyester-cotton blended woven fabrics
Authors: Wang Rui , Xiao Qi
Published: October 2020

Aiming at the classic problem of pilling of polyester-cotton blended woven fabrics, pilling grades were evaluated by image analysis method to study the effects of yarn twist, spinning method, warp, and weft density, fabric cover factor and fabric singeing on pilling performance. The length and density distribution of fabric hairiness was studied by Nano measurer software. The respective roles of polyester and cotton fibers were studied by using scanning electron microscope and quantitative chemical analysis method. The experimental results showed that the factors for the best anti-pilling fabric are that yarn twist is 950 N/m, the spinning method is siro-compact spinning, warp density is 394 N/10cm, weft density is 265 N/10cm, fabric cover factor is 103.9%, and fabric should be singed. Cotton hairiness is fractured, which is wrapped by polyester hairiness to form pills. The frequency distribution of hairiness is approximately given by Gauss distribution. Mass ratio of polyester and cotton hairiness is nearly 66%/34%.
Implant Charge Differences Between Distal Radius Fixation Constructs (CPT 25607, 25608, and 25609)
Authors: Goodman Avi D. , Modest Jacob M. , Johnson Joey P. , Hayda Roman A. , Got Christopher J. , Gil Joseph A. , Weiss Arnold-Peter C.
Published: October 2020

Background:

Implants are a significant contributor to health care costs. We hypothesized that extra-articular fracture patterns would have a lower implant charge than intra-articular fractures and aimed to determine risk factors for increased cost.

Methods:

In total, 163 patients undergoing outpatient distal radius fracture fixation at 2 hospitals were retrospectively reviewed stratified by Current Procedural Terminology codes. Implants and associated charges were noted, as were sex, age, insurance status, surgeon specialty, and location. Bivariate and multivariable regression were used to determine associations.

Results:

Total implant charges were significantly lower for 25607 (extraarticular, $3,348) than 25608 (2-part intraarticular, $3,859) and 25609 (3+ part intraarticular, $3,991). In addition, intra-articular fractures had higher charges for distal screws/pegs and bone graft. Charge was lower when surgery was performed at a trauma center. There was no charge difference associated with insurance status, age, sex, hand surgery specialty, or fellow status. Substantial intersurgeon variation existed in all fracture types.

Conclusion:

Distal radius fractures may represent a good model for examining implant costs. Extra-articular fractures had lower implant charges than intra-articular fractures. These data may be used to help construct pricing for distal radius fracture bundles and potential cost savings.
Comparison of operating room variables, radiation exposure and implant costs for WEB versus stent assisted coiling for treatment of wide neck bifurcation aneurysms
Authors: Rai Ansaar T , Turner Ryan C , Brotman Ryan G , Boo SoHyun
Published: October 2020

Background

The WEB device offers another option for treating wide neck bifurcation aneurysms (WNBA). The objective was to compare procedure variables, radiation and implant cost between WEB and stent assisted coiling (SAC) for WNBA.

Methods

A retrospective comparison of similarly sized WNBA treated with SAC or WEB over 5-years was performed. The operating room (arrival-departure), anesthesia (intubation-extubation), procedure duration (puncture-closure), fluoroscopy time and radiation dose(m-Gy) were recorded from the patients’ charts. Implant cost per case of all implants (stents, coils, WEB) that were opened whether deployed or not was captured including any coils used in the WEB cases. The implant cost represented the true cost incurred by the institution.

Results

There were 46 WEB and 41 SAC cases with no significant difference in aneurysm size. There were more MCA and ACOMM (p = 0.005) and more ruptured aneurysms (p = 0.02) in the WEB group. Regarding procedure variables (hours:minutes): Operating room time WEB 2:31 (±0:37) versus SAC 3:41 (±0:50) (p < 0.0001); anesthesia duration WEB 2:05 (±0:31) versus SAC 3:13 (±0:51) (p < 0.0001) and procedure duration WEB 1:16 (±0:29) versus SAC 2:09 (±0:46) (p < 0.0001). Regarding radiation: Fluoroscopy time WEB 0:34 (±0:18) versus SAC 1:06 (±0:35) (p < 0.0001) and radiation dose WEB 2392(±1086)m-Gy versus SAC 3442 (±1528)m-Gy (p = 0.0007). The implant cost was $17,028(±$5,527) for the WEB versus $23,813 (±$7,456) for the SAC group (p < 0.0001).

Conclusion

The WEB group had significantly shorter operating room, procedure and anesthesia duration compared to the SAC group. The radiation dose and fluoroscopy time was lower for the WEB group. The total implant cost per case was significantly lower for the WEB versus the SAC group.
Woven Endobridge device for treatment of dissection-related PICA aneurysm
Authors: Khattar Nicolas K , White Andrew C , Cruz Aurora S , Adams Shawn W , Meyer Kimberly S , Nauta Haring JW , Ding Dale , James Robert F
Published: October 2020

Ruptured vertebrobasilar dissecting aneurysms require urgent, often challenging treatment as they have with a high re-hemorrhage rate within the first 24 hours. The patient is a 57-year-old woman who presented with severe-sudden onset headache. Further work up showed a ruptured dissecting aneurysm of the caudal loop of the posterior inferior cerebellar artery (PICA) with associated narrowing distally, in the ascending limb. The aneurysm was immediately occluded with a Woven Endobridge (WEB) device (MicroVention, Tustin, CA, USA) while flow diversion treatment of the diseased ascending limb was postponed. Follow-up angiography three months later showed complete occlusion of the aneurysm, as well as healing of the diseased distal vessel, obviating the need for further intervention. WEB embolization of a ruptured dissecting posterior circulation aneurysm provided an excellent outcome for this patient.
The burden of gastroesophageal reflux disease on the cost of managing chronic diseases in Australia. The need for a new diagnostic and management paradigm
Authors: Burton Leticia , Beattie John , Falk Gregory L , Van der Wall Hans , Coman William
Published: October 2020

Introduction

Chronic disease poses a major problem for the Australian healthcare system as the leading cost-burden and cause of death. Gastroesophageal reflux disease (GORD) typifies the problems with a growing prevalence and cost. We hypothesise that a scintigraphic test could optimise the diagnosis, especially in problematic extraoesophageal disease.

Materials and Methods

Data was collected from 2 groups of patients. Patients undergoing fundoplication for severe GORD (n = 30) and those with atypical symptoms (n = 30) were studied by scintigraphy and 24-hour oesophageal pH, impedance and manometry.

Results

Mean age of cohort was 55.8 years with 40 females and 20 males. Body mass index was a mean of 28.3. DeMeester score was normal in 12/60 with atypical symptoms and abnormal in the rest. Good correlation was shown between scintigraphy and impedance, manometry and distal pH readings. Pulmonary aspiration was shown in 25/60 (15 with atypical symptoms) and LPR in 20/30. Several impedance, manometric and scintigraphic finding were good predictors of lung aspiration of refluxate.

Conclusion

Scintigraphy provides a good tool for screening patients with typical and atypical symptoms of GORD. It is well correlated with the standard methods for the diagnosis and provides visual evidence of LPR and lung aspiration.
One-pot synthesis of azo compounds in the absence of acidic or alkaline additives
Authors: Liu Ting-Ting , Yan Jiao-Zhao , Cheng Xin-Wang , Duan Pan , Zeng Yao-Fu
Published: October 2020

A one-pot method for the synthesis of azo compounds by the reaction of β-naphthol with aryl amines using t-BuONO as the nitrosonium source in DCM at room temperature was developed. This method features mild reaction conditions, a simple experimental procedure, and is free of acidic or alkaline additives.
Coaches’ perceived pitfalls in delivering psychological skills training to high-level youth athletes in fencing and football
Authors: Feddersen Niels Boysen , Keis Marcus Alexander Bygballe , Elbe Anne-Marie
Published: October 2020

The current study examined how two high-level coaches in fencing and football perceived the challenges that emerged during a three-month coach education programme aimed at them delivering psychological skills training to athletes. We used action research as the study design and collected data using observations, six semi-structured interviews, and one focus group. We analysed the data using a thematic content analysis. Our findings showed that the coaches struggled with role clarity. The psychological impact was that coaches struggled with identifying the borders between delivering psychological skills training as a part of their coaching and when to refer athletes to sport psychology experts. The coaches also suggested that gaining more knowledge in sport psychology allowed them to analyse the athletes. However, the coaches viewed this as a potential area for abusing trust in the coach-athlete relationship. We suggest that coach education programmes should include content on ethical dilemmas to safeguard against potential abuse of the coach-athlete relationship.
‘Wear Clogs and just Act Normal’: Defining Collectivity in Dutch Domestic Music Concerts
Authors: Vandenberg Femke , Berghman Michaël , van Eijck Koen
Published: October 2020

The last few decades have seen a surge in the consumption of locally produced popular music in the West. Domestic music – music made by national artists and sung in the national language – has gained increasing popularity, specifically within the lower to middle-class segments of the native population. This article uses the Dutch music genre levenslied to explore this growing trend. From a neo-Durkheimian perspective, we can assume the presence of collective effervescence – a shared intensified mood drawn from collective assembly. However, it is less clear how this collectivity is brought about and experienced. In other words, what are the requirements for this state of effervescence to occur? Looking not only at the totems these concertgoers celebrate but also the established symbolic boundaries, can help us understand how the group defines itself, adding to our knowledge of the rise in popularity of domestic music.

We interviewed 20 concertgoers about their experience of these concerts. The analysis finds that the establishment of collectivity is influenced by three symbolic boundaries: (1) intercultural, (2) interclass, and (3) intraclass. Through the negative othering of ethnic monitories – those considered socially higher, and those considered morally lower than themselves – the audiences of these concerts glorify a very narrow image of Dutchness, obtaining a sense of self-worth through the celebration of an idealized national image rooted in nostalgia. The increasing popularity of levenslied concerts (and domestic music more generally) can, therefore, be understood in relation to broader societal changes and connected with a ‘squeezed middle’ class, clinging to tradition and their declining social position.
Risk factors for early readmission after acute exacerbation of chronic obstructive pulmonary disease
Authors: Jo Yong Suk , Rhee Chin Kook , Kim Kyung Joo , Yoo Kwang Ha , Park Yong-Bum
Published: October 2020

Background and aims:

Patients discharged after treatment for acute exacerbation of chronic obstructive pulmonary disease (COPD) are at high risk for readmission. We aimed to identify the prevalence and risk factors for readmission.

Methods:

We included 16,105 patients who had claimed their medical expenses from 1 May 2014 to 1 May 2016 after discharge from any medical facility in Korea, following treatment for acute exacerbation of COPD. We analysed the potential risk factors for readmission within 30 days of discharge.

Results:

Readmission rate was 26.4% (3989 patients among 15,101 patients) and over 50% of readmissions occurred within 10 days of discharge. Approximately 57% of readmissions occurred due to respiratory causes. Major causes of readmission were COPD (27%), pneumonia (14.2%), and lung cancer (7.1%), in that order. Patients who were readmitted were male, had more comorbidities and were less frequently admitted to tertiary hospitals than those who were not readmitted. Risk factors for readmission within 30 days of discharge were male sex, medical aid coverage, longer hospital stay, longer duration of systemic steroid use during hospital stay, high comorbid condition index, and discharge to skilled nursing facility.

Conclusion:

Readmission occurred in approximately one-quarter of patients, and was associated with patient-related and clinical factors. Using these results, we can identify high-risk patients for readmission and precautions are needed to be taken before deciding on a discharge plan. Further research is needed to develop accurate tools for predicting the risk of readmission before discharge, and development and evaluation of an effective care programme for COPD patients are necessary. The reviews of this paper are available via the supplemental material section.
Real-life experiences in a single center: efficacy of pirfenidone in idiopathic pulmonary fibrosis and fibrotic idiopathic non-specific interstitial pneumonia patients
Authors: Feng Haoshen , Zhao Yabin , Li Zhenhua , Kang Jian
Published: October 2020

Background:

Pirfenidone is the first antifibrotic drug approved for the treatment of idiopathic pulmonary fibrosis (IPF) and it is used in the treatment of other interstitial pneumonias, such as unclassifiable interstitial lung disease (ILD) and connective tissue-related ILD. This study examined the efficacy of pirfenidone in patients with IPF and fibrotic idiopathic non-specific interstitial pneumonia (f-iNSIP).

Methods:

In a retrospective real-life study, 67 IPF and 24 f-iNSIP patients were enrolled and classified into a pirfenidone group and a non-antifibrotic group. The level of forced vital capacity (FVC) and diffusing capacity of lung for carbon monoxide (DLco) at baseline, 6, 12 and 24 months were recorded. The level of KL-6 in serum was detected by chemiluminescence enzyme immunoassay (﻿CLEIA). The prognosis and safety outcomes were collected from patients.

Results:

In IPF patients, pirfenidone decreased the mean change of FVC and DLco, and decreased the proportion of patients with a ⩾10% decline in FVC or a ⩾15% decline in DLco compared with the non-antifibrotic group. There was no difference in the mean change of FVC and DLco between smokers and non-smokers who received pirfenidone treatment. There was an improvement in progression-free survival, defined as the time to the first occurrence of acute exacerbation or death related to pulmonary fibrosis. Moreover, the ratio of patients who experienced acute exacerbation and death related to pulmonary fibrosis was lower in the pirfenidone group. There was no change in lung function and prognosis between the pirfenidone and non-antifibrotic groups in f-iNSIP patients. The KL-6 level slightly decreased after 1 year of pirfenidone treatment but not significantly. Gastrointestinal and skin-related adverse events were most common, and four patients ceased treatment due to the side effects.

Conclusions:

Pirfenidone safely reduced disease progression by improving the lung function and progression-free survival in IPF patients, with acceptable side effects. The efficacy of pirfenidone on f-iNSIP was not significant, suggesting the need for further studies. The reviews of this paper are available via the supplemental material section.
Diagnosis of amyopathic dermatomyositis after two intrauterine fetal deaths
Authors: Alonso-Espías M , Martínez-Sánchez N , Robles-Marhuenda A , Martín-Boado ME , Regojo-Zapata RM , Bartha JL
Published: October 2020

Chronic histiocytic intervillositis (CHIV) is an uncommon condition, characterized by an infiltrate of mononuclear cells of maternal origin in the intervillous space that has been related to placenta insufficiency and poor perinatal outcomes. The aetiology is unclear, although maternal immunological aggression toward fetal tissues has been proposed. Dermatomyositis (DM) is a multisystem autoimmune inflammatory myopathy. Different autoantibodies have been associated with particular clinical phenotypes; presence of anti-melanoma differentiation-associated gen 5 (MDA5) antibody has been associated with rapidly progressive interstitial lung disease and severe skin lesions, none of which the woman had. Described here is a case of a woman diagnosed with amyopathic DM with positive anti-MDA5 antibodies after two intrauterine fetal deaths. Pathological examination of the placenta in both pregnancies showed CHIV. The presence of a potential relationship between both processes is discussed.
A challenging case of hypercapnic respiratory failure during pregnancy
Authors: Vijayakumar B , Cao M , Mackillop L , Sarangmat N , Leite MI , Wathen CG , Nickol AH , Turnbull CD
Published: October 2020

We describe a 40-year-old female who presented with progressive breathlessness and hypercapnic respiratory failure during pregnancy secondary to undiagnosed muscle-specific kinase myasthenia gravis. Her presentation was progressive and protracted, having over five contacts with healthcare professionals over nine months, many of these predating her pregnancy. Her atypical presentation for myasthenia with minimal limb weakness led to consideration of other causes of hypercapnic respiratory failure. Once diagnosed, she was treated with intravenous immunoglobulin and non-invasive ventilation. She gave birth to a pre-term infant by planned caesarean section. Her insidious presentation and the progressive nature of her breathlessness were unusual and our report highlights the predominant involvement of respiratory muscles in muscle-specific kinase myasthenia. Her pregnancy may have further delayed her diagnosis due the attribution of some symptoms to normal pregnancy. Early recognition and treatment of myasthenia gravis are important to prevent life-threatening complications.
The sclerosing Sertoli cell tumor of the testis is an extremely rare entity
Authors: Gomha Faaz Salah , Bhatti Kamran Hassan , Yousif Ayad A. , Smain Ayamn Mohammed , Sohail Nadeem , Abdelrahman Khalid Mohammed , Arshad Huma , Shaat Ahmed H. A. , Bhatti Wasim Sarwar , Cheema Naeem Ahmed
Published: October 2020

We present the case of a 31-year-old single male patient, who was admitted through emergency unit with painless hard nodule of his left testis of 6 months’ duration. Ultrasound scan of the scrotum showed a fairly well-defined hypo echoic area in the left testicular parenchyma in its middle part, measuring approximately 10 × 9 mm in size. We performed left inguinal radical orchidectomy. Histopathology examination of the left testis revealed sclerosing Sertoli cell tumor (SSCT) of the testis. This is a very rare testicular tumor with very few published case reports. Systemic examination was performed to exclude systemic metastasis. SSCT is characterized by the presence and aggregates of tubules of Sertoli cells, separated by a sclerotic intercellular matrix formed by fibrotic connective tissue.
Ability of chlorhexidine, octenidine, polyhexanide and chloroxylenol to inhibit metabolism of biofilm-forming clinical multidrug-resistant organisms
Authors: Günther Frank , Blessing Brigitte , Dapunt Ulrike , Mischnik Alexander , Mutters Nico T
Published: October 2020

Purpose:

This in vitro study was designed to determine if standard antiseptics used for skin and environmental surface cleansing can disrupt the metabolic activity (as a measure of viability) of multidrug-resistant gram-negative bacteria, methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus isolates within their native biofilms.

Methods:

Sixty clinical isolates of multidrug-resistant bacteria were selected for testing in different chlorhexidine gluconate, octenidine, polyhexanide and chloroxylenol concentrations. Metabolic inhibition of biofilm for each clinical isolate was analysed using a biofilm viability assay.

Results:

Chlorhexidine gluconate (mean = 83.8% ± 9.8%) and octenidine (mean = 84.5% ± 6.8%) showed the greatest efficacy against biofilms of the tested microorganisms, with the greatest efficacies against MRSA. The antiseptics demonstrated the least efficacy against biofilms of Pseudomonas aeruginosa.

Conclusion:

Chlorhexidine gluconate and octenidine showed the greatest level of bacterial metabolic inhibition and were statistically equivalent. Polyhexanide was more effective than chloroxylenol, but both were inferior to chlorhexidine gluconate and octenidine against the tested organisms.
Effects of Salinity and Suspended Solids on Tropical Phytoplankton Mesocosm Communities
Authors: Sew Genevieve , Todd Peter
Published: October 2020

Phytoplankton play a fundamental role in marine food webs but are affected by both natural and anthropogenic fluctuations in environmental conditions. Here, to simulate a dynamic coastal environment, we used mesocosms to examine how different salinity levels and suspended solids concentrations (SSCs) impact a natural phytoplankton assemblage collected from a tropical estuary in Singapore. Significant differences in the phytoplankton composition between the baseline and treatments with medium and high SSC were found, but not among the three salinities tested. Differences can be attributed to nutrient limitation (particularly silicate) and the use of kaolinite for the suspended sediment. Silicate limitation is likely to have caused the observed switch in dominant genus from Skeletonema sp. to Chaetoceros sp. and the occurrence of weakly silicified genera such as Cylindrotheca. Kaolinite affected phytoplankton abundance through effects such as shading, flocculation, and nutrient adsorption. These results demonstrated how the combination of various physicochemical effects of suspended solids can influence tropical phytoplankton communities. Furthermore, as suspended solids such as kaolin can be found in the natural environment, this study showed that their potential effects should be evaluated beyond just their concentration.
“Because they are connected”: Linking structural inequalities in farmworker organizing
Authors: Sbicca Joshua , Minkoff-Zern Laura-Anne , Coopwood Shelby
Published: October 2020

Agriculture in the United States (US), long dominated by white male interests, is rooted in entrenched structural inequalities. Prominent among them is the power of growers over a dependable low-wage racialized and gendered workforce that is disciplined with the threat of their disposability. Workers and other activists have long responded with opposition. We advance radical food geography scholarship with a relational understanding of the structural inequalities that farmworkers experience and their resistance through farmworker movements, by centering the perspectives and experiences of activists with an intersectional praxis. We begin with a review of the compounding economic, political, and social inequalities experienced by farmworkers in the US in the context of xenophobic enforcement-first approaches to policing documented and undocumented Latinx immigrants. We then present a case study of Community to Community Development (C2C) in Washington state, an example of the radical frontlines of resistance by farmworker advocacy groups, as they link systems of oppression, especially with regard to class, immigration status, gender, and race. Ultimately, we argue for elevating more intersectional forms of organizing in the food system. In doing so, we encourage radical food geographers to conduct scholarship-activism more open to the many intersections between social position and structural inequality and resistance.
The containment of COVID-19 is antithetical to the system of US capitalism
Authors: Montes Vince
Published: October 2020

This paper examines why the US, the wealthiest nation in the world, appears incapable of preventing the spread of COVID-19. The reason is that solutions are antithetical to the US capitalist-state and the continuation of the capitalist system. Since the system is based on private ownership and profit with a sustaining state-sponsored ideology of individualism, it is incapable of enacting the necessary structural changes that can offer the best defense against infectious viruses. A look at its poor record at addressing highly preventable diseases and social problems is foreshadowing.
EU work-family policies revisited: Finally challenging caring roles?
Authors: Weldon-Johns Michelle
Published: October 2020

In 2013 Weldon-Johns used the work-family typology classification model (WFTCM) to analyse the development of EU work-family policies. That examination showed that EU work-family legislation continued to focus on maternal care and was underpinned by the extended motherhood typology. In 2019, the Work-Life Balance for Parents and Carers Directive 2019/1158 was passed, implementing key changes to the EU framework. This article takes this as an opportunity to reflect on the current EU approach. In doing so, it revisits the WFTCM and expands the ideal types to include the shared parental roles typology and redefine the family typology. This analysis shows that while some advances have been made, gendered assumptions surrounding care remain, as does the presumption in favour of childcare. Instead of the Directive fulfilling its potential to challenge caring roles, it is likely that they will continue to be reinforced, although there are some hopes for the future.
Rescue treatment with eltrombopag in refractory cytopenias after allogeneic stem cell transplantation
Authors: Aydin Semra , Dellacasa Chiara , Manetta Sara , Giaccone Luisa , Godio Laura , Iovino Giorgia , Bruno Benedetto , Busca Alessandro
Published: October 2020

Background:

Patients with post-transplant cytopenias due to poor graft function or primary engraftment failure show poor prognosis with a high mortality rate mainly because of graft versus host disease (GVHD), infection and/or bleeding. Treatment options are scarce and a CD34+ stem cell boost or a second bone marrow transplantation may be required to restore adequate haematopoiesis.

Methods:

In the present study patients with primary engraftment failure ( n = 1) and refractory poor graft function ( n = 11) were treated with eltrombopag in a single centre. The reason for eltrombopag treatment was trilineage cytopenia in six patients, bilineage cytopenia in three patients and single lineage cytopenia in three patients. Eltrombopag was initiated at a median of 214 (range: 120–877) days after haematopoietic stem cell transplantation (HCST) and administered for a median time of 114 (range: 12 days to >490) days. In 8/12 patients eltrombopag was introduced at a dose of 75 mg/day and then increased to 150 mg/day after 1 week; 1 patient was given 50 mg eltrombopag per day, and 3 patients received 75 mg daily.

Results:

In 10/12 patients eltrombopag significantly enhanced blood count values and patients became transfusion independent. Once stable haematological response was obtained, treatment was tapered until final discontinuation in 9/10 responding patients. No grade 3 or 4 toxicities were observed. At time of last follow up, 3/12 patients were dead, 2 due to disease relapse, 1 due to GVHD and pneumonia. All patients except one maintained their complete response and remain transfusion independent at a median of 858 (range: 429–1119) days.

Conclusion:

These preliminary data confirm that eltrombopag is able to rescue multilineage haematopoiesis in patients with treatment-refractory cytopenias after allogeneic HSCT.
Body Language Influences on Facial Identification at Passport Control: An Exploration in Virtual Reality
Authors: Tummon Hannah M. , Allen John , Bindemann Markus
Published: October 2020

Person identification at airports requires the matching of a passport photograph to its bearer. One aim of this process is to find identity impostors, who use valid identity documents of similar-looking people to avoid detection. In psychology, this process has been studied extensively with static pairs of face photographs that require identity match (same person shown) versus mismatch (two different people) decisions. However, this approach provides a limited proxy for studying how other factors, such as nonverbal behaviour, affect this task. The current study investigated the influence of body language on facial identity matching within a virtual reality airport environment, by manipulating activity levels of person avatars queueing at passport control. In a series of six experiments, detection of identity mismatches was unaffected when observers were not instructed to utilise body language. By contrast, under explicit instruction to look out for unusual body language, these cues enhanced detection of mismatches but also increased false classification of matches. This effect was driven by increased activity levels rather than body language that simply differed from the behaviour of the majority of passengers. The implications and limitations of these findings are discussed.
Spatial Heterogeneity in Bistable Figure-Ground Perception
Authors: Finlayson Nonie J. , Neacsu Victorita , Schwarzkopf D. S.
Published: October 2020

The appearance of visual objects varies substantially across the visual field. Could such spatial heterogeneity be due to undersampling of the visual field by neurons selective for stimulus categories? Here, we show that which parts of a bistable vase-face image observers perceive as figure and ground depends on the retinal location where the image appears. The spatial patterns of these perceptual biases were similar regardless of whether the images were upright or inverted. Undersampling by neurons tuned to an object class (e.g., faces) or variability in general local versus global processing cannot readily explain this spatial heterogeneity. Rather, these biases could result from idiosyncrasies in low-level sensitivity across the visual field.
Evolving applications of the egg: chorioallantoic membrane assay and ex vivo organotypic culture of materials for bone tissue engineering
Authors: Marshall Karen M , Kanczler Janos M , Oreffo Richard OC
Published: October 2020

The chick chorioallantoic membrane model has been around for over a century, applied in angiogenic, oncology, dental and xenograft research. Despite its often perceived archaic, redolent history, the chorioallantoic membrane assay offers new and exciting opportunities for material and growth factor evaluation in bone tissue engineering. Currently, superior/improved experimental methodology for the chorioallantoic membrane assay are difficult to identify, given an absence of scientific consensus in defining experimental approaches, including timing of inoculation with materials and the analysis of results. In addition, critically, regulatory and welfare issues impact upon experimental designs. Given such disparate points, this review details recent research using the ex vivo chorioallantoic membrane assay and the ex vivo organotypic culture to advance the field of bone tissue engineering, and highlights potential areas of improvement for their application based on recent developments within our group and the tissue engineering field.
Indigenous childhood in Argentina: Parenting, care and formative experiences of Qom and Mbyá children
Authors: García Palacios Mariana , Hecht Ana Carolina , Enriz Noelia
Published: October 2020

Recent investigations in South American anthropology have focused on children in a range of contexts. In ethnographic research with children from indigenous communities in Argentina, we have considered social categories that result in different ways of being a child. In this way, this article presents a model that departs from a traditional, monolithic approach to childhood. The aim is to examine the first stage of life, guided by nominal references, childrearing and the formative experiences of children, with a focus on the network of social relations during this stage of live, particularly, linguistic development, religion and play.
Inflammatory cytokines in the pathogenesis of cardiovascular disease and cancer
Authors: Amin Mohammad Nurul , Siddiqui Shafayet Ahmed , Ibrahim Md , Hakim Md Lukman , Ahammed Md. Salim , Kabir Asma , Sultana Farhana
Published: October 2020

Inflammatory cytokines are highly inducible small glycoproteins or regulatory proteins of low molecular weight secreted by different cell types. They regulate intercellular communication and mediate a number of physiological functions in the human immune system. Numerous prospective studies report that inflammatory cytokines strongly predict coronary artery disease, myocardial infarction, heart failure and other adverse cardiac events. Inflammatory cascade is believed to be a causative factor in the development of atherosclerotic process. Several aspects of atherogenesis are accelerated by cytokines. This article provides an overall overview of current understanding of cytokines in various cardiovascular events. Besides, inflammatory cytokines trigger cellular events that can induce malignancy and carcinogenesis. Elevated expression of several cytokines such as interleukin-1, interleukin-6, interleukin-10, tumor necrosis factor-α, macrophage migration inhibitory factor and transforming growth factor-β are involved in tumor initiation and progression. Thus, they exert a pivotal role in cancer pathogenesis. This review highlights the role of several cytokines in various events of tumorigenesis. Actually, this article summarizes the contributions of cytokines in the pathogenesis of cardiovascular disease and cancer.
Revisiting the Black Box Society by rethinking the political economy of big data
Authors: Brevini Benedetta , Pasquale Frank
Published: October 2020

The Black Box Society was one of first scholarly accounts to propose a social theory of the use of data in constructing personal reputations, new media audiences, and financial power, by illuminating recurrent patterns of power and exploitation in the digital economy. While many corporations have a direct window into our lives through constant, ubiquitous data collection, our knowledge of their inner workings is often partial and incomplete. Closely guarded by private companies and inaccessible to most researchers or the broader public, too much algorithmic decision-making remains a black box to this day. Much has happened since 2015 that vindicates and challenges the book’s main themes. To answer many of the concerns raised in the volume in light of the most recent developments, we have brought together leading thinkers who have explored the interplay of politics, economics, and culture in domains ordered algorithmically by managers, bureaucrats, and technology workers. While the contributions are diverse, a unifying theme animates them. Each offers a sophisticated critique of the interplay between state and market forces in building or eroding the many layers of our common lives, as well as the privatization of spheres of reputation, search, and finance. Unsatisfied with narrow methodologies of economics or political science, they advance politico-economic analysis. They therefore succeed in unveiling the foundational role that the turn to big data has in organizing economic and social relations.
The “black box” at work
Authors: Ajunwa Ifeoma
Published: October 2020

An oversized reliance on big data-driven algorithmic decision-making systems, coupled with a lack of critical inquiry regarding such systems, combine to create the paradoxical “black box” at work. The “black box” simultaneously demands a higher level of transparency from the worker in regard to data collection, while shrouding the decision-making in secrecy, making employer decisions even more opaque to the worker. To access employment, the worker is commanded to divulge highly personal information, and when hired, must submit further still to algorithmic processes of evaluations which will make authoritative claims as to the workers’ productivity. Furthermore, in and out of the workplace, the worker is governed by an invisible data-created leash deploying wearable technology to collect intimate worker data. At all stages, the worker is confronted with a lack of transparency, accountability, or explanation as to the inner workings or even the logic of the “black box” at work. This data revolution of the workplace is alarming for several reasons: (1) the “black box at work” not only serves to conceal disparities in hiring, but could also allow for a level of “data-laundering” that beggars any notion of equal opportunity in employment and (2) there exists, the danger of a “mission creep” attitude to data collection that allows for pervasive surveillance, contributing to the erosion of both the personhood and autonomy of workers. Thus, the “black box at work” not only enables worker domination in the workplace, it deprives the worker of Rawlsian justice.
Good organizational reasons for better medical records: The data work of clinical documentation integrity specialists
Authors: Pine Kathleen H , Bossen Claus
Published: October 2020

Healthcare organizations and workers are under pressure to produce increasingly complete and accurate data for multiple data-intensive endeavors. However, little research has examined the emerging occupations arising to carry out the data work necessary to produce “improved” data sets, or the specific work activities of these emerging data occupations. We describe the work of Clinical Documentation Integrity Specialists (CDIS), an emerging occupation that focuses on improving clinical documentation to produce more detailed and accurate administrative datasets crucial for evolving data-intensive forms of healthcare accountability, management, and research. Using ethnographic methods, we describe the core of CDIS’ work as a translation practice in which the language, interests, and concerns of clinicians and clinical documentation are translated via real-time “nudging” and ongoing education of clinicians into the language, interests, and concerns of medical coders, structured administrative datasets, and the various stakeholders of these datasets. Further, we show how the institutional context of CDIS’ work shapes the occupational virtues that guide CDIS’ translation practice, including financial reimbursement, quality measures, clinical accuracy, and protecting clinician’s time. Despite the existence of these multiple virtues, financial reimbursement is the most prominent virtue guiding CDIS’ limited attention. Thus, overall clinical documentation is “improved” in specific, partial ways. This research provides one of the first studies of the emergent data work occupations arising in the wake of digitization and big data opportunities, and shows how local data settings shape large scale data in specific ways and thus may influence outcomes of analyses based on such data.
Data/infrastructure in the smart city: Understanding the infrastructural power of Citymapper app through technicity of data
Authors: Tavmen Güneş
Published: October 2020

Over the last few years, smart cities have been a focus of scholarly attention. Most of these critical studies concentrated on the multinational corporations’ discourses and their implications on urban policies. Besides these factors, however, the data-driven city develops within a complex web of entanglements whereby data-driven technologies modulate the urban infrastructure in a multitude of ways contingent upon the social, political, material and technical aspects. As such, this article attends to the infrastructural implications of a smart city product, Citymapper, which is a transport app built on open data available as part of London’s smart city planning. In order to establish the relationship between data and infrastructure, I use Gilbert Simondon’s notions of ‘transduction’, ‘individuation’ and ‘technicity’ to explore this relationship in a processual and relational way. In constructing this relationship as co-generative, whereby infrastructure and data transindividuate, I subsequently posit the term data/infrastructure. Against this theoretical background, I study the ways in which Citymapper individuates and thereby gains infrastructural power through technicity of data by studying the ways in which the users’ contribute to data generation that feed back into the app. Specifically, by following the transformation of the app from initially mediating the bus timetable to transducing users into environmental sensing nodes through which the app collects behavioural data, I foreground the epistemological, infrastructural and social consequences of Citymapper’s infrastructural power for the data-driven city.
Personality and job satisfaction among Chinese health practitioners: The mediating role of professional quality of life
Authors: Li Wendy Wen , Xie Guojun
Published: October 2020

This study aims to explore mediating effects of professional quality of life on the relationship between big-five personality traits and job satisfaction in a Chinese healthcare setting. A total of 1620 Chinese healthcare professionals were recruited to participate in a randomised cross-sectional survey. The results suggest that professional quality of life transmitted the effect of personality to job satisfaction. Specifically, compassion satisfaction and burnout mediated the positive effect of extraversion, agreeableness, conscientiousness, and openness upon job satisfaction; as well as mediated negative effects of neuroticism upon job satisfaction. Secondary traumatic stress mediated the positive effect of extraversion upon job satisfaction. The paper also discusses the cultural factors contributing to the mediating effects and implications offered by the study at the macro, messo, and micro levels.
The impact of the face-to-face consultation on decisional conflict in complex decision-making in multiple sclerosis: A pilot study
Authors: Wilkie David Daniel , Solari Alessandra , Nicholas Richard St. John
Published: October 2020

Background

The role of face-to-face consultations in medicine is increasingly being challenged. Disease activity, national guidelines, life goals e.g. pregnancy, multiple therapies and side effects need to be considered on starting disease modifying treatments (DMTs) in people with multiple sclerosis (pwMS).

Objectives

We studied the impact of a face-to-face consultation on decision making, using decisional conflict (DC) as the primary outcome.

Methods

Prospective cohort study of 73 pwMS attending clinics who were making decisions about DMTs followed for one year. Prerequisites and consultation features were measured with the SURE scale for DC used as the primary outcome at baseline and at one year.

Results

The patient activation measure (PAM) was the only driver prior to the consultation associated with DC (p = 0.02) showing those less engaged were more likely to have DC. Overall, 51/73 (70%) of people made their treatment decision or reinforced a former decision during the consultation. We found making a treatment decision between the original consultation and the follow-up was associated with resolving DC (p = 0.008).

Conclusions

Patient engagement impacts DC but the HCP delivering the optimal Shared Decision Making (SDM) approach is additionally significant in reducing DC. In complex decisions there is a clear role for face-to-face consultations in current practice.
Evaluation of a novel latex enhanced turbidimetric immunoassay for detecting autoantibody against extractable nuclear antigens
Authors: Qin Yan , Wu Yanyao , Feng Min , Wang Yanlin , Zhao Xiangcong , Gao Chong , Guo Hui , Luo Jing
Published: October 2020

Detection of autoantibody against extractable nuclear antigens (ENAs) plays a critical role in the diagnosis and management of autoimmune diseases.In this study, we assessed the performance of LETIA in detecting anti-ENAs. Total 606 serum samples from the Second Hospital of Shanxi Medical University were collected. Anti-SSA, anti-SSB, anti-Sm, anti-U1-snRNP, and anti-Sm/RNP were parallelly detected by LETIA and line immunoblot (LIA). Besides, this study assessed LETIA for its repeatability in detecting anti-ENAs autoantibodies, and consistency with LIA. A receiver operating characteristic (ROC) curves was drawn to assess the accuracy of LETIA. The LETIA and LIA showed high coincidence rate in detecting anti-SSA, anti-SSB, anti-Sm, anti-U1-snRNP, and anti-Sm/RNP autoantibodies, with the results being 87.22%, 96.61%, 97.03%, 88.28%, and 92.06%, respectively. Almost perfect consistency (kappa > 0.8) were found in the detection of anti-SSB and anti-Sm by LETIA and LIA. While in the detection of anti-SSA, anti-U1-snRNP, and anti-Sm/RNP, moderate consistency (0.6 ⩽ kappa ⩽ 0.8) were shown. The AUCs of anti-SSA, anti-SSB, anti-Sm, anti-U1-snRNP, and anti-Sm/RNP detected by LETIA were 0.972 (95% confidence interval (CI): 0.941–1.000, p < 0.001), 0.986 (95% CI: 0.967–1.000, p < 0.001), 0.912 (95% CI: 0.763–1.000, p < 0.001), 0.829 (95% CI: 0.731–0.928, p < 0.001), and 0.828 (95% CI: 0.715–0.941, p < 0.001), respectively. LETIA and LIA showed considerable consistency in detecting anti-ENAs. Moreover, with the pronounced advantages of automatic and rapid detection, and high universality, LETIA can meet the requirements for quantitative detection of anti-ENAs.
The relationship between debt and crime: A systematic and scoping review
Authors: van Beek Gercoline , de Vogel Vivienne , van de Mheen Dike
Published: October 2020

Compared to macroeconomic factors, the financial situation of the individual may provide better insight into the relationship between debt and crime. However, the relationship between debt and crime is still unclear and little is known about the causality of this relationship and the factors that influence it. To obtain more insight into this relationship, a systematic and scoping literature review was conducted. Five articles were analyzed in the systematic review, and 24 articles in the scoping review. The results of the systematic review show a strong association between debt and crime whereby debt is a risk factor for crime, especially for recidivism and regardless of the type of crime, and crime is a risk factor for debt. The scoping review provided additional and in-depth insight, and placed the results of the systematic review in a broader perspective. Moreover, it emphasized the prevalence of debt among offenders, regardless of age, and identified the factors that influence the relationship between debt and crime.