bluuebunny/crossref_metadata_2025 huggingface dataset:
Does nutritional counseling in telemedicine improve treatment outcomes for diabetes? A systematic review and meta-analysis of results from 92 studies
Authors: Su Dejun , McBride Chelsea , Zhou Junmin , Kelley Megan S
Published: October 2015

Background

A growing number of studies and reviews have documented the impact of telemedicine on diabetes management. However, no meta-analysis has assessed whether including nutritional counseling as part of a telemedicine program has a significant impact on diabetes outcomes or what kind of nutritional counseling is most effective.

Methods

Original research articles examining the effect of telemedicine interventions on HbA1c levels in patients with Type 1 or Type 2 diabetes were included in this study. A literature search was performed and 92 studies were retained for analysis. We examined stratified results by differentiating interventions using no nutritional counseling from those that used nutritional counseling. We further compared between nutritional counseling administered via short message systems (SMS) such as email and text messages, and nutritional counseling administered via telephone or videoconference.

Results

Telemedicine programs that include a nutritional component show similar effect in diabetes management as those programs that do not. Furthermore, subgroup analysis reveals that nutritional intervention via SMS such as email and text messages is at least as equally effective in reducing HbA1c when compared to personal nutritional counseling with a practitioner over videoconference or telephone.

Conclusion

The inclusion of nutritional counseling as part of a telemedicine program does not make a significant difference to diabetes outcomes. Incorporating nutritional counseling into telemedicine programs via SMS is at least as effective as counseling via telephone or videoconference.
The language of conflict: The relationship between linguistic vitality and conflict intensity
Authors: Medeiros Mike
Published: October 2015

Intergroup conflicts represent a risk of social instability and even violence. Understanding the reasons that push group members to adopt a certain level of conflict intensity is of the utmost importance. In the hope of shedding new light into this phenomenon, this paper explores how ethnic conflict intensity may be influenced by linguistic vitality, the social health of a language. The paper presents a theoretical model in which low and high levels of linguistic vitality are presented as being linked to lower conflict intensity than moderate vitality levels. The results of multilevel modeling lend support to this hypothesis for language-based ethnic tensions in a general context and, more precisely, within countries.
Knowingly not wanting to know: Discourses of people diagnosed with mild cognitive impairment
Authors: Pierce Sian , Lamers Carolien , Salisbury Katie
Published: October 2015

Mild cognitive impairment is a heterogeneous clinical state whereby assessed cognitive changes over time may progress to dementia, remain stable or revert to back to normal. This study aimed to identify, through discourse analysis, how people with a diagnosis of mild cognitive impairment used language in order to reveal the societal views and shared meanings of the diagnosis, and the positions taken by people. Seven people with mild cognitive impairment were interviewed, and three discourses emerged during analysis. One of the discourses revealed was ‘Not Knowing’ about mild cognitive impairment. Furthermore, in the absence of a coherent discourse related to mild cognitive impairment, participants went on to position themselves between two more familiar discourse; ‘Knowing’ about ageing and dying and ‘Not Wanting to Know’ about dementia. Clinicians must consider how information is presented to people about mild cognitive impairment, including where mild cognitive impairment is positioned in respect to normal ageing and dementia.
Development of Nemo remotely operated underwater vehicle for the inspection of the Costa Concordia wreck
Authors: Allotta Benedetto , Brandani Lorenzo , Casagli Nicola , Costanzi Riccardo , Mugnai Francesco , Monni Niccolò , Natalini Marco , Ridolfi Alessandro
Published: October 2015

Remotely operated underwater vehicles are mobile robots increasingly used in underwater applications; these devices are widely used and suitable for different scenarios, for example, for patrolling and monitoring and also for underwater interventions. In the last 30 years, the remotely operated underwater vehicles have become more and more advanced; at the same rate with the progressive technological development of these vehicles, the market of the specialized component industry is fast-increasing. Generally speaking, a remotely operated underwater vehicle allows to investigate areas inaccessible or too dangerous for human beings. The use of remotely operated underwater vehicles during a mission, with the related implication of support ships and specialized pilots, or the involvement of professional divers, is usually associated with high costs. The reduction of these costs is an important topic in the underwater robotic field and the easy piloting of these mobile robots is a crucial aspect in their development. This article describes Nemo remotely operated underwater vehicle, a remotely operated underwater vehicle prototype specifically designed for the exploration of the Costa Concordia wreck, Isola del Giglio, Italy. Nemo remotely operated underwater vehicle can be considered a mini-remotely operated underwater vehicle, that is, a remotely operated underwater vehicle with weight less than 25 kg and easily deployable from a small boat. This article describes the main characteristics of the vehicle: the onboard control logic and on the development of a user-friendly graphical user interface for underwater navigation able to take advantage of its high maneuverability. It is worth to note that the developed graphical user interface enables to operate the vehicle even to inexperienced pilots. Preliminary experimental data collected during navigation are provided.
Parent trigger policies, representation, and the public good
Authors: Allen Ann , Saultz Andrew
Published: October 2015

Using theories of representation and democratic education, this article examines the impetus of parent trigger policies in the United States and their potential effects on public good goals for public education. The article also uses theories of representation and responsible democratic governance to assess the parent trigger policies, or what are often called parent empowerment laws, enacted in seven states.
Is learning styles-based instruction effective? A comprehensive analysis of recent research on learning styles
Authors: Cuevas Joshua
Published: October 2015

In an influential publication in 2009, a group of cognitive psychologists revealed that there was a lack of empirical evidence supporting the concept of learning styles-based instruction and provided guidelines for the type of research design necessary to verify the learning styles hypothesis. This article examined the literature since 2009 to ascertain whether the void has been filled by rigorous studies designed to test the matching hypothesis and identify interaction effects. Correlational and experimental research recently published on learning styles is reviewed, along with an examination of how the subject is portrayed in teacher education texts. Results revealed that the more methodologically sound studies have tended to refute the hypothesis and that a substantial divide continues to exist, with learning styles instruction enjoying broad acceptance in practice, but the majority of research evidence suggesting that it has no benefit to student learning, deepening questions about its validity.
A pedagogy for space: Teaching, learning, and studying in the Baltimore Rebellion
Authors: Ford Derek R
Published: October 2015

While most educational literature on space has tended to ask what spatial studies can offer education, this article works primarily to educationalize theories of space. It does so by homing in on Henri Lefebvre’s theorization of the production of space as a potentially revolutionary activity. After spending some time situating Lefebvre’s historical and theoretical analysis, it takes his understanding of the production of space as an educational problematic, and in turn seeks to develop a spatial educational theory and a pedagogy for space, the latter being the mobilization of the former. In particular, I propose to augment Lefebvre’s spatial triad of (1) spatial practice, (2) representations of space, and (3) representational spaces with an educational triad of (1) teaching, (2) learning, and (3) studying. I propose that each component needs to be held in a precarious, contingent, and dialectical relation. In order to ask more precisely after this relationship and to grasp how we might deploy this educational theory to understand and produce space, I read the theory through the Baltimore Rebellion of 2015. I contend that the Baltimore Rebellion was a struggle over the space of the city, and that it was a deeply pedagogical affair that entailed the orchestration of teaching, learning, and studying.
The role of mycobacterial cell wall nucleic acid complex in the treatment of bacillus Calmette–Guérin failures for non-muscle-invasive bladder cancer
Authors: Packiam Vignesh T. , Pearce Shane M. , Steinberg Gary D.
Published: October 2015

Introduction:

The treatment of high-risk non-muscle-invasive bladder cancer (NMIBC) utilizes transurethral resection followed by adjuvant intravesical immunotherapy or chemotherapy. Intravesical bacillus Calmette–Guérin (BCG) is the mainstay of adjuvant immunotherapy, but there are limited nonsurgical options for patients that fail this treatment. Mycobacterial cell wall nucleic acid complex (MCNA) is an immunotherapeutic agent utilized primarily after failure of intravesical BCG. The purpose of this paper is to provide a comprehensive review of the published literature regarding MCNA.

Methods:

A literature review was performed and identified studies indexed in MEDLINE® related to utilization of MCNA for patients with NMIBC.

Results:

Two trials assessed the efficacy of MCNA in patients with NMIBC, comprising a total of 184 patients. Most patients had carcinoma in situ (CIS) with (26%) or without (52%) concomitant papillary tumors. A minority of patients had only papillary tumors (22%). Most patients (95%) previously received BCG or other intravesical therapy prior to receiving MCNA. In the largest available trial, 25% and 19% of patients had no evidence of residual cancer in 1 and 2 years following initiation of MCNA. A total of 2.3% of patients had adverse events (AEs) leading to delay or discontinuation of therapy and 66% of patients had mild drug-related AEs.

Conclusion:

Based on analysis of available published data, MCNA offers a durable response for a small proportion of patients that have failed prior intravesical therapy. There still exists a large unmet need for nonsurgical treatment options for patients with NMIBC who have failed adjuvant intravesical therapies.
Classification of Physical Activity
Authors: Turksoy Kamuran , Paulino Thiago Marques Luz , Zaharieva Dessi P. , Yavelberg Loren , Jamnik Veronica , Riddell Michael C. , Cinar Ali
Published: October 2015

Physical activity has a wide range of effects on glucose concentrations in type 1 diabetes (T1D) depending on the type (ie, aerobic, anaerobic, mixed) and duration of activity performed. This variability in glucose responses to physical activity makes the development of artificial pancreas (AP) systems challenging. Automatic detection of exercise type and intensity, and its classification as aerobic or anaerobic would provide valuable information to AP control algorithms. This can be achieved by using a multivariable AP approach where biometric variables are measured and reported to the AP at high frequency. We developed a classification system that identifies, in real time, the exercise intensity and its reliance on aerobic or anaerobic metabolism and tested this approach using clinical data collected from 5 persons with T1D and 3 individuals without T1D in a controlled laboratory setting using a variety of common types of physical activity. The classifier had an average sensitivity of 98.7% for physiological data collected over a range of exercise modalities and intensities in these subjects. The classifier will be added as a new module to the integrated multivariable adaptive AP system to enable the detection of aerobic and anaerobic exercise for enhancing the accuracy of insulin infusion strategies during and after exercise.
IDegLira Improves Both Fasting and Postprandial Glucose Control as Demonstrated Using Continuous Glucose Monitoring and a Standardized Meal Test
Authors: Holst Jens J. , Buse John B. , Rodbard Helena W. , Linjawi Sultan , Woo Vincent C. , Boesgaard Trine Welløv , Kvist Kajsa , Gough Stephen C.
Published: October 2015

Objective:

IDegLira is a novel, fixed-ratio combination of the long-acting basal insulin, insulin degludec, and the long-acting glucagon-like peptide-1 analog liraglutide. We studied the effect of IDegLira versus its components on postprandial glucose (PPG) in type 2 diabetes.

Methods:

In this substudy, 260 (15.6%) of the original 1663 patients with inadequate glycemic control participating in a 26-week, open-label trial (DUAL I) were randomized 2:1:1 to once-daily IDegLira, insulin degludec or liraglutide. Continuous glucose monitoring (CGM) for 72 hours and a meal test were performed.

Results:

At week 26, IDegLira produced a significantly greater decrease from baseline in mean PPG increment (normalized iAUC0-4h) than insulin degludec (estimated treatment difference [ETD] −12.79 mg/dl [95% CI: −21.08; −4.68], P = .0023) and a similar magnitude of decrease as liraglutide (ETD −1.62 mg/dl [95% CI: −10.09; 6.67], P = .70). CGM indicated a greater reduction in change from baseline in PPG increment (iAUC0-4h) for IDegLira versus insulin degludec over all 3 main meals (ETD −6.13 mg/dl [95% CI: −10.27, −1.98], P = .0047) and similar reductions versus liraglutide (ETD −1.80 mg/dl [95% CI: −2.52, 5.95], P = .4122). Insulin secretion ratio and static index were greater for IDegLira versus insulin degludec ( P = .048 and P = .006, respectively) and similar to liraglutide ( P = .45 and P = .895, respectively).

Conclusions:

Once-daily IDegLira provides significantly better PPG control following a mixed meal test than insulin degludec. The improvement is at least partially explained by higher endogenous insulin secretion and improved beta cell function with IDegLira. The benefits of liraglutide on PPG control are maintained across all main meals in the combination.
Novel brain MRI abnormalities in Gitelman syndrome
Authors: Beltagi Ahmed El , Norbash Alexander , Vattoth Surjith
Published: October 2015

Gitelman syndrome is an autosomal recessive renal tubular disorder characterized by hypokalemic metabolic alkalosis, hypomagnesemia and hypocalciuria. The syndrome is caused by a defective thiazide-sensitive sodium chloride co-transporter in the distal convoluted tubules of the kidneys. Gitelman syndrome could be confused with Bartter syndrome; the main differentiating feature is the presence of low urinary calcium excretion in the former. Descriptions of neuroradiological imaging findings associated with Gitelman syndrome are very scarce in the literature and include basal ganglia calcification, idiopathic intracranial hypertension and sclerochoroidal calcification. Cauda equina syndrome-like presentation has been reported, but without any corresponding imaging findings on lumbar spine MRI. We report a 13-year-old male with Gitelman syndrome who presented with altered mental status following a fall and scalp laceration and unremarkable brain CT, followed during hospitalization by somnolence and seizures. Metabolically the patient demonstrated hypokalemia and hypomagnesemia. MRI demonstrated features of encephalopathy including predominantly right-sided cerebral hemispheric signal abnormality and cytotoxic edema, with bilateral symmetric involvement of the thalami, midbrain tegmentum and tectum and cerebellar dentate nuclei. MRI after five months obtained during a later episode of encephalopathy showed resolution of the signal abnormalities with setting in of brain atrophy and also areas of newly developed cytotoxic edema in the left thalamus, bilateral dorsal midbrain and right greater than left dentate nuclei. The described abnormalities, either recurrent or in isolation, have not previously been published in patients with Gitelman syndrome. We believe that the findings are due to alteration of respiratory chain function secondary to the metabolic derangement and hence have a similar imaging appearance as encephalopathy related to mitochondrial cytopathy or metabolic encephalopathy.
Mechanical thrombectomy with ‘ADAPT’ technique by transcervical access in acute ischemic stroke
Authors: Castaño Carlos , Remollo Sebastian , García Maria Rosa , Hidalgo Cristina , Hernández-Perez Maria , Ciorba Mihaela
Published: October 2015

Background

The mechanical thrombectomy (MT) for endovascular clot retrieval has dramatically improved successful revascularization and clinical outcome in selected acute stroke patients. MT is typically performed via a transfemoral approach, but catheterization of the occluded vessel can be problematic in cases of extensive vessel tortuosity. We describe a case of MT with the ‘ADAPT’ technique by direct carotid access due to an inability to catheterize the ICA by a transfemoral approach for acute cerebral ischemia in the setting of left MCA occlusion. Excellent angiographic and good clinical results were obtained without any complications.

Case report

An 80-year-old woman was admitted with a stroke by occlusion of the left MCA, with an NIHSS: 11, and an ASPECT: 7 in the CT. Under sedation a transfemoral angiography was performed, but after multiple attempts, it was impossible to make a stable catheterization of the left CCA. A transcervical approach was pursued. With ultrasound guidance the CCA was catheterized. Using the ‘ADAPT’ technique, we performed a successful MT. Post-procedure angiography (at 14 minutes) demonstrated recanalization of the entire left MCA (TICI: 3), without complications. The carotid access point was closed with a percutaneous closure. Control TC at 24 h showed a slight hypodensity in the left lenticular nucleus, and loss of gray-white matter differentiation in the adjacent cortex. Neurologically, the patient presented with progressive improvement. At discharge, she had an NIHSS: 0, mRS: 0 and Barthel: 100.

Conclusions

MT by direct carotid access is an effective alternative technique in those cases where it is not accessible by a transfemoral approach.
Heuristics of the algorithm: Big Data, user interpretation and institutional translation
Authors: Bolin Göran , Andersson Schwarz Jonas
Published: October 2015

Intelligence on mass media audiences was founded on representative statistical samples, analysed by statisticians at the market departments of media corporations. The techniques for aggregating user data in the age of pervasive and ubiquitous personal media (e.g. laptops, smartphones, credit cards/swipe cards and radio-frequency identification) build on large aggregates of information (Big Data) analysed by algorithms that transform data into commodities. While the former technologies were built on socio-economic variables such as age, gender, ethnicity, education, media preferences (i.e. categories recognisable to media users and industry representatives alike), Big Data technologies register consumer choice, geographical position, web movement, and behavioural information in technologically complex ways that for most lay people are too abstract to appreciate the full consequences of. The data mined for pattern recognition privileges relational rather than demographic qualities. We argue that the agency of interpretation at the bottom of market decisions within media companies nevertheless introduces a ‘heuristics of the algorithm’, where the data inevitably becomes translated into social categories. In the paper we argue that although the promise of algorithmically generated data is often implemented in automated systems where human agency gets increasingly distanced from the data collected (it is our technological gadgets that are being surveyed, rather than us as social beings), one can observe a felt need among media users and among industry actors to ‘translate back’ the algorithmically produced relational statistics into ‘traditional’ social parameters. The tenacious social structures within the advertising industries work against the techno-economically driven tendencies within the Big Data economy.
Splenic Marginal Zone Lymphoma in the Setting of Noncirrhotic Portal Hypertension
Authors: Ratnayake Saman , Ammar Ali , Rezvani Rodd , Petersen Greti
Published: October 2015

We present a case of a 65-year-old Hispanic man with a history of disseminated cutaneous coccidioidomycosis who presented to the emergency room for progressively worsening abdominal pain associated with shortness of breath. The patient was found to have pleural effusion and moderate ascites on physical examination. Abdominal ultrasound and computed tomography scan were consistent with moderate ascites and portal hypertension but negative for both liver cirrhosis and for venous or arterial thrombosis. Cytology of ascitic fluid was suggestive of portal hypertension and was negative for infection. Subsequent, thoracentesis was suggestive of exudative effusion and also negative for infection. Liver biopsy confirmed the absence of cirrhosis. Complete blood count indicated pancytopenia, whereas bone marrow biopsy and flow cytometry were suggestive of marginal zone lymphoma (MZL). Clinically, the patient’s shortness of breath was resolved by thoracentesis and paracentesis; however, his abdominal pain persisted. A diagnosis of idiopathic noncirrhotic portal hypertension in the setting of splenic MZL was made. The patient was transferred to a higher level of care for splenectomy; however, he missed multiple appointments. Since discharge, the patient has been seen in the outpatient setting and states that he is controlling his disease with diet and exercise; however, he continues to complain of intermittent shortness of breath with exertion.
Ileal interposition surgery for treatment of type 2 diabetes mellitus-pros and cons
Authors: Payab M. , Hasani-Ranjbar Sh.
Published: October 2015

Nowadays, the surgical techniques for treating type 2 diabetes (T2DM) include: Ileal Interposition (II), Ileal Interposition in combination with Sleeve Gastrectomy (IISG) and Diverted Sleeve Gastrectomy (IIDSG). These procedures are not only for obese subjects, but are also used for non-obese subjects. These types of surgical procedures can improve glycemic control, and lead to a significant reduction in oral hypoglycemic agents (OHAs) and insulin therapy. The results of various studies have shown the safety, feasibility, and efficacy of the surgical procedure for the treatment of T2DM. Although it is an effective treatment option, this procedure is not recommended for general use and long-term studies are needed to confirm these findings and potential side effects on a larger number of patients.
Draft genome sequence of Halomonas meridiana R1t3 isolated from the surface microbiota of the Caribbean Elkhorn coral Acropora palmata
Authors: Meyer Julie L. , Dillard Brian A. , Rodgers John M. , Ritchie Kim B. , Paul Valerie J. , Teplitski Max
Published: October 2015

Members of the gammaproteobacterial genus Halomonas are common in marine environments. Halomonas and other members of the Oceanospirillales have recently been identified as prominent members of the surface microbiota of reef-building corals. Halomonas meridiana strain R1t3 was isolated from the surface mucus layer of the scleractinian coral Acropora palmata in 2005 from the Florida Keys. This strain was chosen for genome sequencing to provide insight into the role of commensal heterotrophic bacteria in the coral holobiont. The draft genome consists of 290 scaffolds, totaling 3.5 Mbp in length and contains 3397 protein-coding genes.
Seismic attributes for description of reef growth and channel system evolution — Case study of Intisar E, Libya
Authors: Wang Yichuan , Eichkitz Christoph Georg , Schreilechner Marcellus Gregor , Heinemann Gabor , Davis John C. , Gharsalla Mohammed
Published: October 2015

A 3D seismic survey over the Intisar E field in the Ajdabiya Trough of the Sirte Basin, Libya, revealed a channel-like feature in Eocene carbonates that wraps around the pinnacle reef that contains the reservoir. We have used coherence, curvature, and spectral decomposition seismic attributes to determine the morphology and gray-level co-occurrence matrix attributes to define seismic facies within the feature. These indicated that the channel originated by submarine scouring caused by downslope movement of turbidity currents. Erosion was followed by the deposition of successive layers of carbonate debris in the channel. Stratigraphic correlations with the adjacent pinnacle reef revealed that the channel was cut during the late stage of reef growth, and a second channel formed after the Intisar E reef ceased to grow. Differences in seafloor elevation over the reef probably diverted turbidity currents so channels were not cut into the reef, breaching the reservoir. This interpreted geologic history may explain why some pinnacle reefs in the Intisar complex contained giant reservoirs, whereas others were barren.
Resistivity and induced polarization monitoring of biogas combined with microbial ecology at a brownfield site
Authors: Mendonça Carlos A. , Doherty Rory , Amaral Nathan D. , McPolin Blathnaid , Larkin Michael J. , Ustra Andrea
Published: October 2015

The accumulation of biogenic greenhouse gases (methane, carbon dioxide) in organic sediments is an important factor in the redevelopment and risk management of many brownfield sites. Good practice with brownfield site characterization requires the identification of free-gas phases and pathways that allow its migration and release at the ground surface. Gas pockets trapped in the subsurface have contrasting properties with the surrounding porous media that favor their detection using geophysical methods. We have developed a case study in which pockets of gas were intercepted with multilevel monitoring wells, and their lateral continuity was monitored over time using resistivity. We have developed a novel interpretation procedure based on Archie’s law to evaluate changes in water and gas content with respect to a mean background medium. We have used induced polarization data to account for errors in applying Archie’s law due to the contribution of surface conductivity effects. Mosaics defined by changes in water saturation allowed the recognition of gas migration and groundwater infiltration routes and the association of gas and groundwater fluxes. The inference on flux patterns was analyzed by taking into account pressure measurements in trapped gas reservoirs and by metagenomic analysis of the microbiological content, which was retrieved from suspended sediments in groundwater sampled in multilevel monitoring wells. A conceptual model combining physical and microbiological subsurface processes suggested that biogas trapped at depth may have the ability to quickly travel to the surface.
Microbial ecology and geoelectric responses across a groundwater plume
Authors: Doherty Rory , McPolin Blathnaid , Kulessa Bernd , Frau Alessandra , Kulakova Anna , Allen Christopher C. R. , Larkin Michael J.
Published: October 2015

We have used geophysics, microbiology, and geochemistry to link large-scale (30+ m) geophysical self-potential (SP) responses at a groundwater contaminant plume with its chemistry and microbial ecology of groundwater and soil from in and around it. We have found that microbially mediated transformation of ammonia to nitrite, nitrate, and nitrogen gas was likely to have promoted a well-defined electrochemical gradient at the edge of the plume, which dominated the SP response. Phylogenetic analysis demonstrated that the plume fringe or anode of the geobattery was dominated by electrogens and biodegradative microorganisms including Proteobacteria alongside Geobacteraceae, Desulfobulbaceae, and Nitrosomonadaceae. The uncultivated candidate phylum OD1 dominated uncontaminated areas of the site. We defined the redox boundary at the plume edge using the calculated and observed electric SP geophysical measurements. Conductive soils and waste acted as an electronic conductor, which was dominated by abiotic iron cycling processes that sequester electrons generated at the plume fringe. We have suggested that such geoelectric phenomena can act as indicators of natural attenuation processes that control groundwater plumes. Further work is required to monitor electron transfer across the geoelectric dipole to fully define this phenomenon as a geobattery. This approach can be used as a novel way of monitoring microbial activity around the degradation of contaminated groundwater plumes or to monitor in situ bioelectric systems designed to manage groundwater plumes.
Development and pilot testing of a mental healthcare plan in Nepal
Authors: Jordans M. J. D. , Luitel N. P. , Pokhrel P. , Patel V.
Published: October 2015

Background

Mental health service delivery models that are grounded in the local context are needed to address the substantial treatment gap in low- and middle-income countries.

Aims

To present the development, and content, of a mental healthcare plan (MHCP) in Nepal and assess initial feasibility.

Method

A mixed methods formative study was conducted. Routine monitoring and evaluation data, including client flow and reports of satisfaction, were obtained from patients (n = 135) during the pilot-testing phase in two health facilities.

Results

The resulting MHCP consists of 12 packages, divided over community, health facility and organisation platforms. Service implementation data support the real-life applicability of the MHCP, with reasonable treatment uptake. Key barriers were identified and addressed, namely dissatisfaction with privacy, perceived burden among health workers and high drop-out rates.

Conclusions

The MHCP follows a collaborative care model encompassing community and primary healthcare interventions.
Truth Becomes Fiction When Fiction Is True: The Story of the Stone and the Visual Culture of the Manchu Court
Authors: Wei Shang
Published: October 2015

This paper seeks to interpret The Story of the Stone with reference to the visual culture of the Manchu court. It argues that the Yongzheng reign (1723–1735) inaugurated a new era of visual culture when jia (the unreal or fiction) became itself a productive concept and an indispensable visual device in the illusionistic paintings and interior decoration of the Manchu palaces and gardens. In addressing the intricate interplay and intersections of zhen (the real or true) and jia, The Story of the Stone does more than rehash an inherited literary theme or rhetorical device. Drawing heavily on the contemporary paintings and decorative art of the imperial court, it gives both a gripping expression to and a sophisticated spin on the visual penchant and sensibility of the Manchu royal house and aristocracy.
Simultaneous imaging of blood flow dynamics and vascular remodelling during development
Authors: Ghaffari Siavash , Leask Richard L. , Jones Elizabeth A.V.
Published: October 2015

Normal vascular development requires blood flow. Time-lapse imaging techniques have revolutionized our understanding of developmental biology, but measuring changes in blood flow dynamics has met with limited success. Ultrasound Biomicroscopy and Optical Coherence Tomography can concurrently image vascular structure and blood flow velocity, but these techniques lack the resolution to accurately calculate fluid forces such as shear stress. This is important because hemodynamic forces are biologically active and induce changes in expression of genes important for vascular development. Regional variations in shear stress, rather than the overall level, control processes such as vessel enlargement and regression during vascular remodelling. We present a technique to concurrently visualize vascular remodelling and blood flow dynamics. We use an avian embryonic model and inject an endothelial-specific dye and fluorescent microspheres. The motion of the microspheres is captured with a high-speed camera and the velocity of the blood flow in and out of the region of interest is quantified by micro-particle image velocitymetry (μPIV). The vessel geometry and flow are used to numerically solve the flow physics with computational fluid dynamics (CFD). Using this technique, we can analyse changes in shear stress, pressure drops and blood flow velocities over a period of 10 to 16 hours. We apply this to study the relationship between shear stress and chronic changes in vessel diameter during embryonic development, both in normal development and after TGF-β stimulation. This technique allows us to study the interaction of biomolecular and biomechanical signals during vascular remodelling using an in vivo developmental model.
Energy-Harvesting Mechanisms for UAV Flight by Dynamic Soaring
Authors: Bonnin V. , Benard E. , Moschetta J.-M. , Toomer C. A.
Published: October 2015

Dynamic Soaring is a flying technique which extracts energy from an environment where wind gradients form, with the potential to increase the endurance of small unmanned vehicles. The feasibility to use dynamic soaring flight is questioned here; it requires the identification of energy-extraction mechanisms as well as accurate understanding of the way energy-harvesting performances are governed by trajectory constraints, vehicle characteristics and environment conditions. A three-dimensional energy-neutral trajectory is derived out of a specified optimization problem. Characteristic phases of flight are evidenced out of an overall closed trajectory. Simplified equations are used to evidence the physics behind energy transfers. Finally, overall energy-harvesting balance is studied through local variations of total energy along the path.
Experimental Investigation of Micro Air Vehicle Scale Helicopter Rotor in Hover
Authors: Benedict Moble , Winslow Justin , Hasnain Zohaib , Chopra Inderjit
Published: October 2015

This paper describes a fundamental experimental study, which involved systematic performance and flowfield measurements (PIV) to understand and optimize the hover performance of a MAV-scale helicopter rotor operating at Reynolds numbers lower than 30,000. The rotor parameters that were varied include blade airfoil profile, blade chord, number of blades, blade twist, planform taper and winglets at blade tip. Blade airfoil section had a significant impact on the hover efficiency and among the large number of airfoil sections tested, the ones with the lower thickness to chord ratios and moderate camber (4.5% to 6.5%) produced the highest rotor hover figure of merit. Increasing the solidity of the rotor by increasing the number blades (with constant blade chord) had minimal effect on efficiency; whereas, increasing the solidity by increasing blade chord for a 2-bladed rotor, significantly improved hover efficiency. Moderate blade twist (−10° to −20°) and large planform taper (larger than 0.5) marginally improved rotor efficiency. Rotor blades with small winglets (height ≈ 6% of rotor radius) at the tip also improved hover performance. While using winglets, the flowfield measurements showed a diffused tip vortex, which could reduce the induced aerodynamic losses. Spanwise lift distribution obtained using sectional bound circulation computed from the measured flowfield correlated well with the load cell measurements. The optimal rotor designed based on the understanding gained from the present study produced a figure of merit of 0.67, which is the highest value of FM ever reported in the literature for micro-rotors operating at these low Reynolds numbers.
Dynamic Simulation of an Unmanned Hybrid Flying Robot
Authors: Alsaif khalid A. , Foda Mosaad A. , Rosyid Abdur
Published: October 2015

This paper considers the dynamic simulation of an Unmanned Hybrid Flying Robot (UHFR) with main fuel engine in the middle to carry most of the weight and promises long flights. This configuration will increase the flight time of the unmanned copter for a given payload size as opposed to the traditional quad-copters, where only DC motors are used. A parametric study to investigate the effect of the propellers ratio (main rotor propeller diameter to secondary rotor propeller diameter), the angle of incidence of the main rotor and the twist angle of the main rotor blades on selected performance criteria of the UHFR is presented.
An Evaluation of Multi-Rotor Unmanned Aircraft as Flying Wind Sensors
Authors: Marino Matthew , Fisher Alex , Clothier Reece , Watkins Simon , Prudden Samuel , Leung Chung Sing
Published: October 2015

This paper examines the possibility of using a Multi-Rotor Unmanned Aircraft System (MUAS) for atmospheric flow measurements around a tall building. This novel sensing approach is proposed, whereby we attempt to determine the oncoming flow velocity magnitude and direction from measurements of the power required by each of the MUAS rotors. Extensive wind-tunnel testing was completed to determine the power required by the fore and aft rotor-pairs at varying flow velocities and directions. The results show that it is possible to map between rotor power consumption and the oncoming flow vectors, however, a unique and accurate mapping is only possible over a very small region of the measurement space. Thus, it is concluded that the practical use of this sensing method is limited. Examination of power consumption curves also revealed that the conditions under which a Vortex Ring State (VRS) develops for small MUAS. The characteristics of VRS development are similar to those of full-size helicopters, indicating that the VRS is Reynolds number independent. The reduction in power consumption due to the presence of updraft flows of various magnitudes was also quantified, indicating that significant endurance improvements of MUAS are possible and can be achieved when operating windward of large buildings.
A Review of Biomimetic Air Vehicle Research: 1984-2014
Authors: Ward Thomas A. , Rezadad M. , Fearday Christopher J. , Viyapuri Rubentheren
Published: October 2015

Biomimetic air vehicles (BAV) are a class of unmanned aircraft that mimic the flapping wing kinematics of flying organisms (e.g. birds, bats, and insects). Research into BAV has rapidly expanded over the last 30 years. In this paper, we present a comprehensive bibliometric review of engineering and biology journal articles that were published on this subject between 1984 and 2014. These articles are organized into five topical categories: aerodynamics, guidance and control, mechanisms, structures and materials, and system design. All of the articles are compartmented into one of these categories based on their primary focus. Several aspects of these articles are examined: publication year, number of citations, journal, authoring organization and country, non-academic funding sources, and the flying organism focused upon for bio-mimicry. This review provides useful information on the state of the art of BAV research and insight on potential future directions. Our intention is that this will serve as a resource for those already engaged in BAV research and enable insight that promotes further research interest.
Valuable Novelty: A Proposed General Theory of Innovation and Innovativeness
Authors: Stauffer Dennis A.
Published: October 2015

A general theory of innovation is proposed based on an analysis of the common characteristics and dynamics of two innovation archetypes, natural selection and the scientific method, along with innovation in other contexts such as business and technology. This Valuable Novelty Theory posits a probabilistic pattern of innovation called the Innovation Cycle and a complimentary pattern called the Status Quo Cycle. This approach is designed in part to enable the measurement and comparison of innovativeness across a variety of activities, disciplines, and contexts. Two companion articles apply and test this theory.

This paper is one of three published in series, following a hypothetical deductive approach. This first article lays a theoretical foundation. The second article, “Evaluating Mindset as a Means of Measuring Innovativeness,” explains the creation of an evaluation instrument that applies this theory. A third article, “Innovativeness as a Predictor of Entrepreneurial Value Creation,” uses that instrument to test the theory’s predictive capabilities.
A New Approach to Assess the Changing Growth Model of Open National Innovation Systems
Authors: Chang Shu-Hao , Chen Carey Ming-Li
Published: October 2015

The open innovation paradigm is an important topic of management thought in national innovation systems. Previous studies of open national innovation systems have almost always focused on concepts or theoretical exploration. There is a great lack of integrated frameworks for the process and mechanism of open national innovation systems. Therefore, the research adopts a structural approach and provides an open national innovation model to verify the influence of different mechanisms on open innovation outputs. As well, we argue that open national innovation systems will change over time, as the mechanisms are dynamic, linking, and coexistent. The study adopts a latent growth curve model to verify the growth tendency and progressive change. The policymaker’s perspective of exploring open national innovation systems is important. Building open national innovation capabilities is based on cumulativeness conditions, diffusion capabilities, and international linkages. The results show that cumulativeness conditions and international linkages will positively affect the growth rate of open innovation outputs. Consequently, this study adopts a dynamic experimental map to validate the relationship of the dimensions to provide government with some practical suggestions for making effective policy.
Preparation for the audit and the audit of the enterprise electronic industry with a view to improving the management and organization of production
Authors: Малахов  , Malakhov A. , Долгун  , Dolgun G. , Яньков  , Yankov A. , Шнайдер  , Shnayder A.
Published: October 2015

The article deals with the preparation for the audit and audit enterprise electronics industry with a view to improving the management and organization of production
Modelling of the mechanical properties of wood filler
Authors: Стородубцева  , Storodubtseva Tamara , Аксомитный  , Aksomitnyy Aleksey
Published: October 2015

The problem of using wood waste is highly relevant. A mathematical model of the structure and mechanical properties of wood composite, allowing theoretically study the dependence of the strength properties of the composite from the fractional composition and concentration of the timber. This article presents the results of research on the project, to win the competition awards the Youth Government of the Voronezh region, with the support of youth programs and projects.
What Difference Does a Robot Make? The Material Enactment of Distributed Coordination
Authors: Beane Matt , Orlikowski Wanda J.
Published: October 2015

What difference does robotic telepresence make to the coordination of complex, dynamic, and distributed knowledge work? We explored this question in a post-surgical intensive care unit where medical workers struggled to coordinate their work in the face of different assessments of their extremely sick patients. Our in-depth field study examined night rounds, a central routine for coordinating work in this unit that was performed remotely through different technologies. We found that night rounds that are materially enacted through robotic telepresence intensify coordination outcomes both positively and negatively, resulting in contrary implications for subsequent coordination of work. We further found that these differences in intensification depend on whether preparatory work is more or less distanced from the bedside. We develop a theoretical account of these findings by explaining how the coordination of complex, dynamic, and distributed work is crucially related to how that work is materially enacted over time.
Men's health 12: men and suicide
Authors: Barber Chris
Published: October 2015

Suicide is one of the last great taboos within society and those who either attempt or actually commit suicide are some of the most challenging people to work with, partly because those who contemplate, attempt or commit suicide may unearth often deep-seated feelings and emotions within those who care for them. This article sets out to explore the meaning and forms of suicide and the roles of the healthcare assistants (HCAs) who work with this client group.
The economic and emotional costs of endoparasitic worm burdens in cats and dogs
Authors: Wright Ian
Published: October 2015

Roundworm and tapeworm infection remain common in UK cats and dogs, leading to extensive attempts to control infection. This is primarily due to human and animal health concerns, but the economic and emotional costs of these parasites are often not considered. This article focuses on two groups of worms. Toxocara spp. are the most common nematodes in cats and dogs and thought to lead to significant human morbidity as a zoonosis, which is difficult to quantify nationally. Tapeworms are a quantifiable and major source of economic losses due to meat and offal condemnation, and Echinococcus granulosus remains a serious endemic zoonosis. Control measures are discussed in terms of limiting economic and zoonotic impact as well as strengthening the human-animal bond.
Patterns of disease in patients at a tertiary referral centre requiring reoperative parathyroidectomy
Authors: McIntyre CJ , Allen JLY , Constantinides VA , Jackson JE , Tolley NS , Palazzo FF
Published: October 2015

Introduction

Reoperative parathyroidectomy is required when there is persistent or recurrent hyperparathyroidism following the initial surgery (at least 5% of parathyroidectomies nationally). By convention, ‘persistent disease’ is defined as the situation where the patient has not been cured by the first operation. The term ‘recurrent hyperparathyroidism’ is used when the patient was confirmed to be biochemically cured for six months from the first operation but has hyperparathyroidism after this date. Reoperative surgery is associated with higher rates of postoperative complications as well as a greater rate of failure to cure. The aim of our study was to review our departmental experience of reoperative parathyroidectomy, with a view to identify patterns of disease persistence and recurrence.

Methods

Using a departmental database, patients were identified who had undergone reoperative parathyroidectomy between 2006 and 2014. All the pre, intra and postoperative information was documented including the operative note so as to record the location of the abnormal parathyroid gland found at reoperation.

Results

Almost two-thirds (63%) of patients had negative, equivocal or discordant conventional imaging so secondary investigative tools were required frequently. The majority of abnormal glands were found in eutopic locations. The most common locations for ectopic glands were intrathyroidal, mediastinal and intrathymic. A third (33%) of the patients had multigland disease and over a quarter (28%) had coexisting thyroid disease.

Conclusions

Persistent hyperparathyroidism represents a challenging patient subgroup for which access to all radiological modalities and intraoperative parathyroid hormone monitoring are required. Patient selection for reintervention is a key determinant in the reoperation cure rate.