bluuebunny/crossref_metadata_2025 huggingface dataset:
On the question of target refraction with femtolasik in patients with hypermetropia
Authors:   FSAI ", Kuznetsova O.S. ,   S.N. Fedorov National Medical Research Center ",   MNTK ",   Eye Microsurgery",   of Healthcare of the Russian Federation, Volgograd Branch, Balalin S.V. ,   FSAI "S.N. Fedorov National Medical Research Center "MNTK "Eye Microsurgery" of Healthcare of the Russian Federation, Volgograd Branch,   FSBEI HE "Volgograd State Medical University" of the Ministry of Healthcare of the Russian Federation, Department of ophthalmology ICMPE
Published: October 2022

Based on the clinical and functional results obtained in 233 patients with mild to moderate hyperopia (233 eyes) before and after FemtoLASIK, formulas were derived to determine the required optimal amount of laser correction, and nomograms were compiled for FemtoLASIK planning in patients with mild and moderate hyperopia. Keywords: hypermetropia, FemtoLASIK, target refraction.
A clinical case of intraoperative prevention of capsular block during cilio-capsular fixation of a three-piece IOL
Authors:   S.N. Fyodorov Eye Microsurgery Federal State Institution of the Russian Ministry of Health, Moscow, Gasanova H.S. , Panteleev E.N. ,   S.N. Fyodorov Eye Microsurgery Federal State Institution of the Russian Ministry of Health, Moscow, Taevere M.R. ,   S.N. Fyodorov Eye Microsurgery Federal State Institution of the Russian Ministry of Health, Moscow, Shikhalieva E.A. ,   S.N. Fyodorov Eye Microsurgery Federal State Institution of the Russian Ministry of Health, Moscow
Published: October 2022

Purpose. To evaluate the clinical efficacy of intraoperative peripheral capsulotomy of the anterior leaf of the preserved capsular sac for the prevention of capsular block during fixation of the haptic elements of a three-piece IOL in the ciliary sulcus and infringement of the optics in the anterior capsulorhexis. Material and methods. Clinical results of phacoemulsification of complicated cataract with femtosecond laser accompaniment against the background of pseudoexfoliation syndrome, grade I subluxation in a 58-year-old patient in the early postoperative period. In addition to standard examination methods, optical coherence tomography of the anterior segment of the eye was used. During the operation, after filling the haptic elements of the three-part IOL into the ciliary sulcus, and the optics into the anterior capsulorhexis, 0.3 mm to the periphery from the edge of the IOL optics with a spear knife, two peripheral capsulotomies of the anterior capsule were performed opposite to each other. Results. On the 2nd day after the operation, BCVA increased and amounted to 1.0, IOP - 11 mm Hg. Art.; before surgery - 0.6 and 22, respectively. According to optical coherence tomography, a sufficient distance between the edge of the iris and the anterior surface of the IOL for free circulation of intraocular fluid was determined, and there were no signs of a capsular block. Conclusion. In the course of the study, it was found that intraoperative peripheral capsulotomy of the anterior leaf of the capsular bag provided natural leaching of viscoelastic from the capsular bag during implantation of a three-piece IOL into the ciliary sulcus with infringement of the optic part in the anterior capsulorhexis on the second day after the operation. Key words: capsular block, capsulotomy, three-piece intraocular lens, cilio-capsular fixation, pseudoexfoliative syndrome.
The first experience of implantation of AcrySoft IQ Vivity IOL
Authors:   Cheboksary branch of the Federal State Educational Institution NMIC MNTC ", Kulikov I.V. ,   Eye Microsurgery",   named after Academician S.N. Fedorov, Ministry of Health of Russia, Cheboksary, Russia, Timofeeva N.S. ,   Cheboksary branch of the Federal State Educational Institution NMIC MNTC "Eye Microsurgery" named after Academician S.N. Fedorov, Ministry of Health of Russia, Cheboksary, Russia, Nikolaeva I.P. ,   State Autonomous Institution of the Chuvash Republic of Additional Professional Education "Institute of Advanced Training of Doctors" of the Ministry of Health of the Chuvash Republic, Cheboksary, Russia, Pozdeeva N.A. ,   Cheboksary branch of the Federal State Educational Institution NMIC MNTC "Eye Microsurgery" named after Academician S.N. Fedorov, Ministry of Health of Russia, Cheboksary, Russia
Published: October 2022

The article presents the first results of implantation of the intraocular multifocal EDOF lens AcrySof IQ Vivity after femtolaser-assisted cataract extraction Keywords: cataract, femtosecond laser-assisted cataract surgery, multifocal intraocular lens, IOL AcrySof IQ Vivity, FLACS.
The typology of South Ural fortified settlements Bronze Age
Authors: Ульчицкий Олег Александрович
Published: October 2022

В статье представлены результаты научного исследования по разработке типологии укрепленных поселений Южного Урала эпохи бронзы на основе анализа объемно-планировочной структуры. Вводятся четыре базовых критерия: объемно-планировочная структура по характеру планировки, размер поселения с учетом прилегающей территории, морфология по форме плана и уровень мощности фортификации. В результате исследования составлена таблица, в которой отображается генезис объектов, даются рекомендации по использованию результатов исследования применительно к визуализации системных связей.

The article presents the results of a scientific study on the development of a typology of fortified settlements in the Southern Urals of the Bronze Age, based on an analysis of the space-planning structure. Four basic criteria are introduced: the space-planning structure according to the nature of the layout, the size of the settlement, taking into account the adjacent territory, the morphology according to the form of the plan, and the level of fortification thickness. As a result of the study, a table was compiled that displays the genesis of objects, recommendations are given on the use of the study results in relation to the visualization of system relationships.
УПРАВЛЕНИЕ КАЧЕСТВОМ И БЕЗОПАСНОСТЬЮ ПОЛУКОПЧЕНЫХ КОЛБАС С ОЛЕНИНОЙ
Authors: Яшкин Александр Иванович
Published: October 2022

К оленине относят мясо северных оленей, маралов, лосей и других представителей семейства оленьих. На возможность использования мяса маралов для промышленной переработки в Сибири указывают хорошие мясные качества животных и устойчивый рост поголовья в Республике Алтай. Использование оленины в колбасном производстве обосновано в исследованиях ученых СФНЦА, но остаются неизученными конкретные меры по снижению биологических, химических и физических рисков на различных этапах производства продукции. Цель настоящей работы состояла в разработке технологических приемов управления рисками на основе принципов ХАССП в производстве полукопченой колбасы с олениной. В работе использована оленина (мясо марала) (Республика Алтай). Данные химического состава мяса показали высокое содержание в сырье белка (20,5 %), жира (3,4 %) и золы (2,1 %). В работе над программой ХАССП составлена детализированная блок-схема производства колбасного изделия с олениной, обоснованы операционные точки, в которых необходим контроль температурно-влажностных режимов для предупреждения биологических рисков: дефростация мяса, охлаждение и сушка колбас. Процессы разделки, обвалки и жиловки мяса, а также взвешивания специй и добавок включают меры по предупреждению рисков физической природы в виде наличия в сырье обломков кости и посторонних предметов. Критической контрольной точкой являются процессы варки и копчения колбас, направленные на минимизацию уровня биологических и химических опасных факторов. Для каждой точки контроля установлено сочетание мер управления, предложена система корректирующих действий.
ИСПОЛЬЗОВАНИЕ ПРОРОЩЕННОГО ЗЕРНА ОВСА ГОЛОЗЕРНОГО В ТЕХНОЛОГИИ СМУЗИ
Authors: Снегирева Анна Владимировна , Мелёшкина Лариса Егоровна
Published: October 2022

В статье рассмотрена возможность использования пророщенного зерна овса голозерного в технологии смузи. В качестве вкусовых компонентов выбраны плоды облепихи свежемороженой и тыквенный сок. Актуальность темы подтверждена многочисленными научными исследованиями о необходимости потребления продуктов, являющихся источниками пищевых волокон, в частности, бета-глюкана, содержащегося в зерновых культурах. Указано, что в процессе проращивания содержание бета-глюкана возрастает. Рассмотрены проблемы питания современного населения и на основании изучения литературных данных показана польза внесения пророщенного овса голозерного в рецептуру смузи. Исследованы изменения, происходящие в овсе голозерном в результате проращивания (изменение длины ростка, кислотности и влажности). Подобраны режимы подготовки пророщенного зерна для внесения в напиток на основании изучения влияния длительности измельчения на размер частиц. Проведена оценка влияния дозировки пророщенного овса на стабильность консистенции напитка путем определения длительности оседания частиц. Подобрана дозировка плодов облепихи в смузи, при которой формируются наилучшие органолептические показатели. На основании расчетов установлено, что массовая доля пищевых волокон в порции разработанного напитка составила 8,2 г, что на 41 % удовлетворяет суточную потребность в данном веществе.
SUBJECTS OF PROTECTION OF THE RIGHTS AND LEGAL INTERESTS OF A GROUP OF PERSONS: ISSUES OF TERMINOLOGY
Authors: Афтахова Александра Васильевна
Published: October 2022

Статья посвящена анализу терминов, определяющих субъектов искового производства по делам о защите прав и законных интересов группы лиц в рамках гражданского судопроизводства. Автор формулирует предложения по изменению нормативно-правового регулирования в части классификации субъектов искового производства по делам о защите прав и законных интересов группы лиц.

The article is devoted to the analysis of the terms that define the subjects of action proceedings in cases on the protection of the rights and legitimate interests of a group of persons in the framework of civil proceedings. The author formulates proposals for changing the legal regulation in terms of classifying the subjects of action proceedings in cases of protecting the rights and legitimate interests of a group of persons.
SUBJECTIVENESS OF INTERPRETATION OF COMPOSITE GOODS IN FOREIGN ECONOMIC ACTIVITIES
Authors: Субботин Юрий Борисович
Published: October 2022

Рассматривается вопрос неформализованного подхода к интерпретации составных товаров для таможенных целей. Отсутствие граничных критериев при классификации товаров в соответствии с товарной номенклатурой внешнеэкономической деятельности (ТН ВЭД) может привести к различным результатам идентификации товара разными субъектами таможенных правоотношений и, как следствие, к разным мерам тарифного и нетарифного регулирования по товару.

The issue of a non-formalized approach to the interpretation of composite goods for customs purposes is considered. The absence of boundary criteria in the classification of goods in accordance with the commodity nomenclature of foreign economic activity (TN VED) can lead to different results of product identification by different subjects of customs legal relations and, as a result, to different measures of tariff and non-tariff regulation of the product.
Współczesne dylematy związane z podjęciem się roli opiekuna rodzinnego starszej osoby
Authors: Tobiasz-Adamczyk Beata , Florek Marzena , Luśtyk Michalina
Published: October 2022

W ostatnich dekadach różne aspekty sprawowania opieki przez nieformalnych opiekunów rodzinnych nad starszymi członkami rodziny stały się przedmiotem wzrastającego zainteresowania ze strony badaczy. Obserwowane zmiany w strukturze i zasadach funkcjonowania współczesnej rodziny skłaniają do postawienia pytania o jej odpowiedzialność za sprawowanie opieki nad starszymi współmałżonkami, rodzicami i dziadkami. Szczególną uwagę zwracano na konsekwencje zdrowotne i psychospołeczne wynikające z negatywnych, stresujących doświadczeń związanych z trajektorią pełnienia tej roli. Zmianie uległy także koncepcje teoretyczne poświęcone zapewnieniu rodzinnej opieki – klasyczny model solidarności międzypokoleniowej został zastąpiony modelem ambiwalencji, który w ostatnim czasie został wyparty przez nowy model, koncentrujący się na znaczeniu indywidualnej decyzji o dokonaniu wyboru wejścia w rolę opiekuna rodzinnego, niezależnie od presji społecznej wynikającej z kulturowych norm i zobowiązań. Na podstawie przeglądu literatury przeanalizowano demograficzne i psychospołeczne uwarunkowania decyzji przyjęcia roli opiekuna rodzinnego i przedstawiono wyniki przeprowadzonego sondażu. Pytanie, czy pełnienie roli opiekuna rodzinnego jest wpisane w przyszły scenariusz życia osób niesprawujących aktualnie tej funkcji, zadane zostało 213 respondentom w wieku 35–65 lat. Uzyskane wyniki wskazują, że mniej niż połowa badanych rozważa przyjęcie w razie potrzeby takiej roli – przy czym wejście w przyszłości w rolę opiekuna było istotnie zależne od poczucia przynależności i więzi wewnątrzrodzinnych, ukształtowanych we wcześniejszych etapach życia rodziny. Istotne statystycznie różnice w planach życiowych dotyczących opieki odnotowano w zależności od wieku (częściej planowały takie działania osoby młodsze i aktywne zawodowo), natomiast nie potwierdzono istotnych różnic w zależności od płci badanych. Badani wyrażający gotowość przyjęcia roli opiekuna wiązali swoje przyszłe zadania z okazywaniem wsparcia emocjonalnego i spędzaniem czasu z osobą starszą, natomiast trudy codziennej instrumentalnej pomocy nie były przez nich w pełni brane pod uwagę.
Edukacja społeczna szczepionką na infodemię? Eksploracja kapitału zdrowotnego podczas pandemii COVID-19 w Polsce
Authors: Świątkiewicz-Mośny Maria , Ślusarczyk Magdalena , Prokop-Dorner Anna , Ożegalska-Łukasik Natalia , Potysz-Rzyman Aleksandra
Published: October 2022

Wyzwania wynikające z globalnego kryzysu zdrowotnego i infodemii ujawniły znaczenie kapitału zdrowotnego. Wychodząc od wielowymiarowej definicji Anny Schneider-Kamp [2021], analizujemy istniejące i potencjalne zasoby dostępne Polakom i Polkom w czasie pandemii. W artykule przyglądamy się znaczeniu kompetencji zdrowotnych dla dbania o zdrowie i poszukiwania wiarygodnych informacji na temat epidemii. Podejmujemy kwestię strategii, jakie kobiety i mężczyźni wykorzystywali w zarządzaniu pandemicznie zmienioną codziennością w Polsce. Bazując na dostępnych badaniach, analizujemy także oddziaływanie kapitałów społecznego i ekonomicznego na sytuację zdrowotną jednostek i grup osób w kontekście wynikających z epidemii zmian życia rodzinnego, zawodowego czy indywidualnego. Przyjmując założenie, że stosunek do szczepień przeciwko COVID-19 jest wskaźnikiem tego, w jaki sposób kapitał zdrowotny został zagospodarowany, badamy postawy Polaków i Polek wobec szczepienia się przeciwko koronawirusowi. W końcu bierzemy na warsztat zdrowotne oddziaływania edukacyjne, prowadzone w Polsce przez agendy państwa, jak i te oddolne, i wskazujemy, które z nich mają szansę przyczynić się do rozwoju kapitału zdrowotnego, a które sprawiają wrażenie działań pozorowanych.
Elementy historycznoprawne w antyukraińskiej propagandzie Federacji Rosyjskiej w latach 2013–2022
Authors: Fijałkowska Lena
Published: October 2022

Przedmiot badań: Przedmiotem analizy są argumenty historycznoprawne, które znalazły zastosowanie w kampaniach propagandowych skierowanych przeciw Ukrainie.

Cel badawczy: Celem badań było ustalenie, w jaki sposób historia prawa wykorzystywana jest w wojnie informacyjnej z Ukrainą, na jakich wydarzeniach skupia się rosyjska narracja historyczna, jakie żądania i dążenia uzasadnia i w jaki sposób to robi.

Metoda badawcza: W badaniach oparto się na analizie piśmiennictwa oraz przemówień i innych wypowiedzi prezydenta Rosji, a także treści propagandowych zawartych w rosyjskich mediach.

Wyniki: Analiza wykazała, że historia prawa stanowi istotne narzędzie w wojnie informacyjnej prowadzonej przeciw Ukrainie. Narracja rosyjska koncentruje się przy tym na tych wydarzeniach, które da się zinterpretować w sposób pozwalający na podkreślenie odwiecznej jedności narodów rosyjskiego, ukraińskiego i białoruskiego, przy jednoczesnym zanegowaniu pełnej samodzielności Ukrainy. Ziemie zajęte w roku 2014 uznaje się za historycznie rosyjskie, zaś imperialna przeszłość Rosji służy jako uzasadnienie dla tworzenia strefy wpływów obejmującej obszar poradziecki. Z kolei usprawiedliwieniem agresji zarówno z 2014 r., jak i z lutego 2022 r. ma być odradzający się na Ukrainie faszyzm, którego dowód stanowić ma kult Stepana Bandery
Oddalenie powództwa oczywiście bezzasadnego w świetle art. 6 EKPC
Authors: Jaroniewska Anna
Published: October 2022

Przedmiot badań: Nowelizacją z 4 lipca 2019 r. do Kodeksu postępowania cywilnego wprowadzono szereg istotnych dla polskiej procedury cywilnej zmian. Jedną z nich jest uregulowana w art. 1911 możliwość oddalenia na posiedzeniu niejawnym przez sąd powództwa w przypadku jego oczywistej bezzasadności. Instytucja ta wywołuje kontrowersje w zakresie urzeczywistniania prawa jednostki do sądu. Na mocy komentowanego przepisu sąd może dokonać oceny wniesionego powództwa w początkowym stadium rozpoznania sprawy, bez podejmowania jakichkolwiek czynności. Z jednej strony zatem przepis ten realizuje postulat usprawnienia postępowania, natomiast z drugiej – w przypadku oddalenia powództwa, a następnie uprawomocnienia się wydanego w tym przedmiocie wyroku, zachodzi res iudicata, która uniemożliwia ponowne dochodzenie przez powoda tego samego roszczenia przeciwko tej samej osobie na drodze sądowej, co pociąga za sobą dotkliwe konsekwencje.

Cel badawczy: Zasadniczym celem artykułu jest zbadanie zgodności instytucji oddalenia powództwa oczywiście bezzasadnego z prawem do sądu zagwarantowanym zarówno przez ustawodawcę krajowego, jak i akty prawa europejskiego. Autorka opracowania podda również pod rozwagę, czy Europejski Trybunał Praw Człowieka może stwierdzić naruszenie przez sąd krajowy prawa dostępu do sądu, pomimo analogii instytucji oddalenia powództwa jako oczywiście bezzasadnego oraz instytucji odrzucenia przez ETPC skargi w trybie art. 35 Konwencji.

Metoda badawcza: W niniejszym artykule zastosowano metodę językowo-logiczną oraz prawno-porównawczą. Wykorzystując analizę komparatystyczną, ukazano aktualne orzecznictwo ETPC oraz sądów polskich.

Wyniki: Instytucja oddalenia powództwa jako oczywiście bezzasadnego niewątpliwie służy przyspieszeniu postępowania cywilnego. Jest również dopuszczalna w świetle praw zagwarantowanych w Europejskiej Konwencji Praw Człowieka, w szczególności jej art. 6, jednak wyłącznie w sytuacji, gdy nie narusza ona istoty prawa do sądu i urzeczywistnia właściwy cel
Toward Buryat-Yakut Ethnic Connections: İgidäi and Eχirid. Addendum: Ikirezh(ъ), Itirit
Authors:   Institute for Mongolian, Buddhist and Tibetan Studies, Nanzatov B. Z. , Tishin V. V. ,   Institute for Mongolian, Buddhist and Tibetan Studies
Published: October 2022

The article presented to be a continuation of the study of the Buryat ethnonym Eχirid ~ Eχired (to be Ekhirit in Russian spelling) published by its authors earlier. That result of previous analysis was provided the linguistic argument to confirm the position, previously expressed by colleagues without any argumentation, that the ethnonym İgidäi reflected in the name of political and then administrative unit (nasleg) among the Yakuts should be considered as a form related to the Buryat ethnonym Eχired < Ekired. At the same time earlier the authors of the article presented had proposed that the spelling ikirezh(ъ) found in Russian documents of the 17th century reflected the form of the original Eχirid ~ Eχired in the genitive case. It should be understood as the form with the suffix +i known in the Ekhirit-Bulagat dialects of Buryat language, determined the palatalization and further affricatization of the preceding consonant -d: [d] > *[ɟ] > [dʑ]. Now an attraction of additional source materials allows one to reinforce an argument for that assumption. It may be the most interesting the possibility of defining the last consonant as palatalized in a typologically close example that is the mention of the ethnonym “Ikinyazhskiy” or “Ikinyatskiy” in Russian spelling in the same documents to reflect the original form *ikinädʹ(i). In the article presented it is also considered the tribal name “Itiritskiy (rod)” attested in Russian spelling in the 1897 census among the Yakut population. Following the hypothesis about the connection of this name with the Buryat ethnonym Eχirid ~ Eχired, the authors propose to interpret the Russian spelling “Itiritskiy” mentioned as the reflecting an original form the emergence of which was a result of the phonetic change *ikired > *itʹired due to palatalization of the original [k] > [tʹ] in a language close to Buryat type. The results of the study not only allow one to detail information about the Buryat-Yakut historical contacts, but also supplement information about the historical phonetics of the Buryat language.
La Iniciativa HEARTS en Cuba: experiencias tras 5 años de implementación
Authors: Valdés González Yamilé , Morejón Giraldoni Alain , Pérez Perea Lizette , Jiménez Chiquet Amarilys , López Lima Carlos , Campbell Norm , Giraldo Gloria
Published: October 2022

Con el propósito de describir los cambios en el control de la hipertensión arterial desde 2016 a 2021 y la relación de los progresos con la madurez de implementación de la Iniciativa HEARTS en el primer nivel de atención de Cuba, se diseñó un estudio prospectivo de implementación que promovió la medición correcta de la presión arterial con esfigmomanómetros automáticos validados, la atención basada en riesgo, la introducción de protocolos de tratamiento antihipertensivo estandarizado, la prevención secundaria y el trabajo en equipo. Se fomentó además la educación a pacientes, la búsqueda activa de casos y las actividades comunitarias. Los datos se obtuvieron de los registros de implementación y fueron analizados con el programa estadístico SPSS versión 21, se reportan las medidas de resultados y sus intervalos de confianza del 95%. Se evaluaron los indicadores poblacionales: cobertura de registro, control entre tratados, control poblacional, así como el índice de madurez de procesos de HEARTS en Las Américas. Comparativamente, entre los años 2016 y 2021 aumentaron los centros participantes, desde un centro de demostración hasta 22 policlínicos en 6 provincias y 7 municipios. Se evidenció un incremento significativo en los valores absolutos del total de población atendida, el número de hipertensos registrados, de pacientes controlados entre los tratados e hipertensos controlados entre todos los adultos, aunque con variaciones anuales en los porcentajes de cobertura, control entre tratados y control poblacional. Los mayores progresos ocurrieron en los centros con equipos de salud de alto desempeño. Cinco años después de la implementación de la Iniciativa HEARTS en Cuba se transita hacia la institucionalización de la metodología.
RT-qPCR Made Simple: A Comprehensive Guide on the Methods, Advantages, Disadvantages, and Everything in Between
Authors: Mehta Nidhi
Published: October 2022

Introduction: In the world of science, many technologies and methodologies exist to contribute to the process of research. Polymerase Chain Reaction (PCR) is a technology that aids in amplifying specific DNA sequences. PCR can be used to determine the presence of a certain DNA gene. In contrast, reverse transcriptase quantitative PCR (RT-qPCR) converts ribonucleic acids (RNA) into complementary DNA (cDNA) which can then be amplified to give a Ct (threshold cycle) value, a representation of how much of the original RNA transcript was present in the sample.
Utility: RT-qPCR is a technique that can be used in many areas of research, including forensic pathology to identify individuals through polymorphic repetitive regions of the DNA called short tandem repeats. This method can also be used in diagnosing various viral diseases such as the recent COVID-19 virus. RT-qPCR is also used in numerous laboratory procedures, such as determining cell growth, cell survival, genetic persistence, and more.
Challenges: This method does come with many challenges, such as determining the normalization technique to be used in order to effectively compare the Ct value of the sample with the Ct value of the control gene, as there are numerous ways to perform this comparison. This challenge can be mitigated by establishing a common technique within each lab. Determining which housekeeping gene should be used in the normalization process is also a persistent challenge. This can be addressed by researching the different genes and determining which housekeeping gene will best be established as an accurate control. Ensuring the purification of RNA and gathering knowledge of a few base pairs to design primers are other challenges that must be considered as well but can be resolved fairly easily.
Limitations: Limitations such as the difficulty in replication can hinder the reliability of the method. The ‘Monte Carlo’ effect and the lack of an established method for normalization further contribute to the difficulty in comparing studies with differing RT-qPCR protocols used. These limitations can be addressed by publishing data with the exact conditions and methods used in the RT-qPCR reaction.
KIF3C Promotes the Malignant Progression of Lung Cancer Cells A549
Authors: Liu Haiwang , Liu Ran , Hao Meiling , Zhao Xing , Li Chunhui
Published: October 2022

Objective: To investigate the role of KIF3C gene in promoting the malignant phenotype of lung cancer cells and in regulating PI3K/AKT signaling pathway. Methods: CCK-8 and transwell assays were used to detect the changes in cell proliferation and cell migration ability after being transfected with siKIF3C, as well as the protein expression levels of PI3K, p-PI3K, AKT, and p-AKT following the downregulation of KIF3C by Western blot. Results: The CCK-8 assay showed that the proliferation/viability of lung cancer cells A549 significantly reduced after being transfected with siKIF3C gene (P < 0.05); the migration ability of lung cancer cells A549 was significantly reduced after transfected with siKIF3C gene (P < 0.05); the levels of p-PI3K and p-AKT proteins were downregulated after KIF3C protein knockdown (P < 0.05); however, the detection of PI3K and AKT protein levels was not statistically significant. Conclusion: KIF3C may promote the proliferation and migration ability of lung cancer cells A549 through PI3K/AKT signaling pathway.
The Formation of the Najjāriyya and Their Theology
Authors: MAHMUT Rami İbrahim
Published: October 2022

The regions of Khorāsān and its environs had witnessed a great intellectual renaissance in various fields, whether in Islamic theology, jurisprudence, or other disciplines. Starting from the era of al-Ma'mūn, the Mu’tazilites emerged as a sect representing the authority. The Ṭāhirid State was established as a pro-Ma'mūn state in Khorāsān and helped to consolidate such a renaissance. The aforementioned regions had witnessed a lot of theological sects and many adherents of Islamic schools of thought. There were many debates and discussions among all these sects, especially during the notorious ordeal of the Creation of the Qur'an, which was spearheaded by the Mu'tazilites who forced people to adhere to their belief. The Najjārī Sect emerged from the womb of the Mu'tazila, the founder of the Sect, Al-Hussein bin Muhammad Al-Najjār, was described by sources as one of the greatest theologians as he was a student of the famous Mu'tazilite Bishr Al-Marīsī. Afterwards, Al-Najjār formed a new doctrine, in which he combined many opinions from different theological schools of Islamic thought. More than ten sects have emerged from the Najjārī Sect; the most famous of which are the Borghoūthis, the Mustadrikas and the Za’farānis. This paper aims to shed light on the Najjārī Sect by providing a brief on the city of Ray as it was the hub of activity for the main sects of the Najjārīs. In addition, a synopsis of the theological opinions of the Najjārī sects shall be presented based on books of discourses (Maqālāt) and Islamic sects.
IN THE FACE OF. FOCUS SHIFT IN CONDITIONS OF ACTIVE LANGUAGE CONTACTS
Authors:   Moscow State Linguistic University, Evtushenko Olga V.
Published: October 2022

The article is devoted to the analysis of the influence of international languages on each other at the level of cognitive structures. The paper considers the mistakes made by the interpreters of international organizations in the design of the left and right context of the preposition in the face of, and it is concluded that the reason for such errors is the wrong choice of the conceptual base of the preposition in the conditions of competition between two metaphorical cognitive models – CONFRONTATION and APPEAL (with a model COURT). The base imposes referential, morphological and semantic restrictions on the filling of the left and right context of the preposition in the face of. The study of the materials of the National Corpus of the Russian Language, including the historical corpus, showed that the cognitive model APPEAL was more often activated by those who wrote in Church Slavonic, and then in Russian, then the model CONFRONTATION. The established discursive practice ensured the dominance of the cognitive model APPEAL in cognitive structures of modern Russian speakers. An analysis of the use of in the face of and face à, as well as other phraseological units with face in English and face in French, showed that the cognitive model CONFRONTATION is more significant for their speakers. Currently, under the influence of the languages of global communication in the Russian language, there is an increase in the compatibility of the preposition in the face of and an increase in the importance of the cognitive model CONFRONTATION.
WHAT DOES IT “LOSE FACE” MEAN IN RUSSIAN?
Authors:   Lomonosov Moscow State University, Bogdanova Lyudmila I.
Published: October 2022

The article deals with the semantic uncertainty of the phraseologism to lose face in the modern Russian language. The purpose of the study is to establish the evaluative characteristics of “loss of face” in the context of other moral “losses” (lose shame, lose conscience). The work was carried out on the material of explanatory and phraseological dictionaries of the Russian language with the use of data from the National Corpus of the Russian Language. In the course of the study, methods and operational procedures were used, including contextual analysis of phraseological unit syntagmatics, elements of component and frame analysis, methods of equivalent substitutions and context transformations. The study found that the “loss of face” in the Russian language occupies a special position among other significant moral losses. “To lose conscience, shame” denotes the loss of morally valuable qualities denoted by these words, and is understood unambiguously in this regard. The polysemy of the word face leads to the fact that the phraseological units lose face can convey a whole range of meanings, among which the main ones are the following: loss of individuality, distinctive personality traits, loss of reputation and respect in the eyes of others, loss of control over oneself, one’s emotions. The evaluative characteristics of the phraseological unit to lose face also differ from the evaluation of “loss of shame” or “loss of conscience”. “Loss of shame (conscience)” receives public censure; “loss of face” is negatively evaluated and painfully realized by the subject himself.
POST-HEMORRHAGIC HYDROCEPHALUS IN NEWBORNS. ANALYSIS OF TREATMENT RESULTS
Authors: Volkodav O. , Zinchenko S. , Khachatryan W.
Published: October 2022

A retrospective analysis of 480 newborns with post-hemorrhagic hydrocephalus was carried out for the period 2000-2018 years. Decompensation of cerebrospinal fluid dynamics (CSFD) was observed in 189 children. It is noted that quantitative indicators of dynamic of secondary reduction of periventricular brain density (PBD) in CSFD can serve as criteria for objective evaluation in the differential analysis of hypertensive and posthypoxic (ischemic) genesis of brain damage. The proposed algorithm correction of post-hemorrhagic hydrocephalus using methods of coronary-lambdoid subarachno-ventriculostomy and ventriculo-subarachnoid stenting expands the potential of early pathogenesis treatment with an increase in the surgical index of stabilization of CSFD, restoration of intracranial circulation and absorption of liquor.
Analisis Problematika Evaluasi Pembelajaran IPA Pada Masa Pandemi: Kajian Literatur
Authors: Idrus Syarifa Wahidah Al
Published: October 2022

Penelitian ini bertujuan untuk mendiskripsikan problematika evaluasi pembelajaran IPA pada masa pandemi (Covid 19). Penelitian ini menggunakan metode studi literatur dengan mengkaji 6 artikel internasional dan 1 artikel nasional terakreditasi. Hasil kajian menunjukkan beberapa problem evaluasi yang muncul pada pembelajaran daring. Problem yang muncul antara lain masalah teknis, masalah komunikasi, masalah metode, dan masalah siswa. Selain itu problematika muncul mulai dari, kesulitan guru membuat kisi-kisi, analisis instrument. Pada proses pelaksanaan masalah yang muncul adalah kurang tepat dalam menentukan teknik evaluasi dengan metode daring dan kesulitan untuk mengevaluasi sikap selama proses daring.
RECOMENDAÇÕES E ESTRATÉGICAS ODONTOLÓGICAS EM PACIENTES COM SÍNDROME CORONÁRIA AGUDA EM USO DE TERAPIA ANTIPLAQUETÁRIA:UM NOVO CONCEITO
Authors:   Sociedade de Cardiologia do Estado de São Paulo (SOCESP). Departamento de Odontologia, Buhatem Medeiros Frederico ,   Hospital Samaritano. Equipe de Odontologia Hospitalar, de Souza Cantoni Valéria Cristina ,   Instituto Dante Pazzanese de Cardiologia (IDPC). Seção de Odontologia., Leão de Souza Abizaid Andrea Claudia ,   Instituto Dante Pazzanese de Cardiologia (IDPC). Seção Médica de Angioplastia. São Paulo, Ribeiro Carvalho Aristéa ,   Universidade de São Paulo. Faculdade de Odontologia de Bauru. Departamento de Cirurgia, Estomatologia,, Augusto Siscotto Tobias Matheus ,   Universidade de São Paulo. Faculdade de Odontologia de Bauru. Departamento de Cirurgia, Estomatologia,, de Andrade Buhatem Medeiros Ana Carolina ,   Sociedade de Cardiologia do Estado de São Paulo (SOCESP). Departamento de Odontologia,   Instituto Dante Pazzanese de Cardiologia (IDPC). Seção de Odontologia.
Published: October 2022

As doenças cardiovasculares representam uma das principais causas de morbi-mortalidade no mundo ocidental. Neste cenário, as síndromes coronarianas agudas (SCA) respondem pela grande maioria dos eventos fatais. A terapia antiplaquetária única e dupla (DAPT), constituída de ácido acetilsalicílico (AAS) associada a um inibidor da P2Y12, tem sido o componente essencial do tratamento da fase aguda da SCA. Neste artigo, daremos ênfase aos pacientes que realizam cirurgias odontológicas na vigência da DAPT. Material e Métodos: Este estudo é uma revisão integrativa da literatura, por meio da pesquisa bibliográfica, e foram incluídos artigos publicados em inglês, disponíveis online, na íntegra, e que mencionavam extração dentária em indivíduos em terapia antiplaquetária. Resultados: Dentre 1026 artigos, após exclusão de revisões, foram incluídos neste estudo apenas 14, com as seguintes variáveis consideradas relevantes: autor e ano de publicação, título do artigo, amostra, terapia medicamentosa, objetivo, exame laboratorial, metodologia antiplaquetária, incidência de complicações, hemostáticos locais e conclusão. Discussão: Os estudos descritos mostraram um baixo número de complicações associadas a pequenos procedimentos cirúrgicos orais sem interrupção desses medicamentos e quase todos relataram taxas de sangramento perioperatório aceitáveis com diferentes esquemas antiplaquetários. Entretanto, devemos ponderar os fatores clínicos associados que aumentam o risco de sangramento para a individualização das recomendações em cirurgias odontológicas nos pacientes em uso de terapia antiplaquetária. Conclusão: Não é recomendada a suspensão da terapia medicamentosa, seja única ou dupla, frente ao receio de maiores sangramentos em cirurgias orais — exodontias. Os métodos hemostáticos locais devem ser sempre utilizados para um bom controle da hemostasia local.
PENGARUH PERPUTARAN KAS DAN PERPUTARAN PERSEDIAAN TERHADAP PROFITABILITAS (STUDI KASUS DI BUMDES SUMBER REZEKI TAMBUSAI TIMUR)
Authors: Riski Yolanda
Published: October 2022

Penelitian ini bertujuan untuk mengetahui pengaruh perputaran kas dan perputaran persediaan secara simultan terhadap profitabilitas BUMDesa Sumber Rezeki. Peneitian ini termasuk jenis penelitian kuantitatif. Populasi dan sampel dari penelitian ini adalah data laporan keuangan BUMDesa Sumber Rezeki tahun 2015-2020. Metode penarikan sampel dengan menggunakan tekhnik sampling jenuh. Tekhnik analisis yang digunakan yaitu analisis linier berganda. Hasil penelitian berdasarkan analisis regresi linier berganda mennjukkan bahwa: (1) Perputaran kas berpengaruh signifikan terhadap profitabilitas BUMDesa Sumber Rezeki, (2) Perputaran persediaan berpengaruh signifikan terhadap profitabilitas BUMDesa Sumber Rezeki. Kesimpulan dari penelitian ini adalah pada pengujian secara persial dan simultan variabel perputaran kas dan perputaran persediaan memiliki pengaruh signifikan terhadap profitabilitas BUMDesa Sumber Rezeki Tambusai Timur 2015-2020.
Ta’ṡīru Istikhdāmi Wasā’iṭi YouTube fī Dāfi’i Ihtimāmi li Ta’līmi al Lughati al ‘Arabiyyati bi al Madrasati al Ṡānawiyyati al Ikhlāṣi al Islāmiyyati Jāmbī
Authors: Solehati Lia , Prihartini Yogia
Published: October 2022

Abstract:The objectives of this research are: a) to find out how big the influence of learning Arabic by using YouTube media is. b) to find out how big the influence of learning Arabic without using YouTube media is. c) to find out whether there is an effect of learning Arabic using YouTube media on the interest of students at SMP Al-Ikhlas Jambi City. This research is a quantitative research with the type of experimental research with Post test Only Control Design. Calibration of the instruments used are Validity Test, Reability Test, Difficulty Level, Distinctive Power. Data analysis methods used are: Normality Test, Homogeneity Test, Hypothesis Testing (T-Test / Independent Sample T-Test) and Effect Size. The subjects are class VIII A students with a total of 19 as the experimental class and class VIII B with a total of 19 as the control class. Based on the results of research data analysis, it is known that learning Arabic using YouTube media on the questionnaire (questionnaire) got the highest score of 99.00, the lowest was 62.00, the average value was 80.95 and the test results got the highest score, namely 100 , the lowest is 40 , the average value is 85.25 . and learning Arabic without using youtube media and the results of the questionnaire (questionnaire) got the highest score of 92.00, the lowest was 60.00, the average value was 73.63 and the test results got the highest score of 100, the lowest was 40, the average score -the average is 66.84. So it is proven that learning Arabic using youtube media is higher than learning Arabic without using youtube media. 0.033 <0.05 and the test results obtained a 2-tailed value <0.05, namely 0.00 <0.05 then Ha is accepted, meaning that there is a significant difference between students' interest in learning Arabic by using YouTube media and interest in learning Arabic. Arabic students without using YouTube media. Meanwhile, based on the Effect Size Test, the results of the questionnaire (questionnaire) obtained a value of 0.941 with an effect percentage of 82% and on the test questions obtained a value of 0.717 with a percentage effect of 76% which means that the use of YouTube media has a high influence on the interest in learning Arabic for students in junior high school. Al-Ikhlas Jambi city.
Effect of Intravenously Injected Arachidonic Acid on Electrocardiography in Rats
Authors: KAŞIKÇI Esra , YALÇIN Murat
Published: October 2022

Arachidonic acid (AA), which is released from phospholipids in the cell membrane by a variety of stimuli, has physiological and pathophysiological roles on the cardiovascular system. The current study designed to determine the effect of intravenously (iv) injected AA on the electrocardiography (ECG) of the anesthetized rats.

The ECG waves obtained from the lead II were written by placing electrodes to limbs of the ketamine and xylazine mixture (50 mg/kg/20 mg/kg; im) anesthetized adult Spraque Dawley rats. AA (3 mg/kg; iv) statistically significantly (p
Linguistic Representation of Religious Power in the Early Medieval Anglo-Saxon Linguoculture (by the Material of the Poem “Beowulf” and the “Anglo-Saxon Chronicle”)
Authors: Gogenko Victoria Vladimirovna , Palashevskaya Irina Vladimirovna
Published: October 2022

The research aims to determine the verbal ways of representing religious power in the Anglo-Saxon linguoculture of the early Middle Ages recorded in Anglo-Saxon texts presented in Old English. The research material is the early medieval written narrative texts of the poem “Beowulf” and the annals of the “Anglo-Saxon Chronicle”. Scientific novelty of the research lies in shedding light on and clarifying attributes of religious power. The boundaries of the semantic space of religious power were defined, the linguistic means of its representation were described, the behavioural attributes of religious rulers represented in epic and chronicle texts were revealed. As a result, the researchers have identified and characterised groups of lexemes naming representatives of religious power, their attributive collocability, as well as the main groups of religious verbs presented by written sources.
Status of Maxims in the Phraseology of the French Language (by the Material of French Weather Maxims)
Authors: Varzinova Valentina Vitalievna
Published: October 2022

The purpose of the study is to determine the status of weather maxims among other idiomatic expressions of the French language based on the material of set expressions containing weather maxims. The main hypothesis of the study is that weather maxims, being a part of separate collections, have a special lexico-grammatical structure in comparison with other French phraseological units. The study is novel in that it is the first to demonstrate the specificity of the structure of French weather maxims. As a result, the author presents the lexical and grammatical features of French weather maxims, which makes it possible to talk about their special status.
Colour Naming Units in Chinese Poetic Texts of the Tang Era
Authors: Popova Olga Aleksandrovna , Grigorova Elena Alekseevna , Omarova Leyla Alakberovna
Published: October 2022

The study aims to identify the role of colour terms in the Chinese poetry of the Tang era (VII-X centuries). The paper is novel in that it is the first to analyse the main colour naming units in Chinese poetic texts of the Tang era, to determine that poets of this period use colour terms not only to convey meanings that are traditional for Chinese culture, but also to express the author’s individuality and their own worldview. As a result, it has been proved that colour naming units can convey a wide range of meanings, which are often completely opposite, in the Chinese poetry of the Tang era. The most common colour terms in the poetry of this period are white and blue-green, indicating the significance of the themes of spiritual insight and renewal of life for poets.
The LIFE Concept as a Representative of the Cultural Subtext in N. N. Tolstaya’s Short Stories “To Be like Everyone Else” and “The View from the Window”
Authors: Rakova Irina Vladimirovna
Published: October 2022

The aim of the study is to identify the cultural subtext in N. N. Tolstaya’s short stories “To Be like Everyone Else” and “The View from the Window” through semantic variants of the notional concept LIFE. Scientific novelty of the paper lies in considering the notional concept within the framework of intertexts as a representative of the national cognitive space in a specific time period. As a result of the study, it was possible to determine that a notional concept, when it is within “intertext blocks”, is able to manifest the peculiarities of the linguistic consciousness of a nation that are characteristic of a certain time period and demonstrate the extralinguistic reality of any given historical stage. In particular, N. N. Tolstaya’s texts revealed semantic variants reflecting the cultural situation in the Soviet Union during the post-war years and in the 60s, as well as the peculiarities of the worldview and ideology of those periods.
Allusion Interpretation Using the Mental Space Theory (by the Material of the English Language)
Authors: Potylitsina Irina Gennadievna , Eremina Natalia Konstantinovna
Published: October 2022

The purpose of the study is to apply the mental space theory to the interpretation of allusion in the text of Charles Lamb’s essay “A Chapter on Ears” (1823). The paper focuses on the fact that allusion is a dynamic structure of knowledge; it acts as a mental representation of the corresponding fragment of the surrounding reality in the text (discourse). Therefore, it seems reasonable to consider the process of allusion interpretation as a cognitive-discursive model based on the interaction of the mental spaces of the pretext and the allusive (recipient) text. Scientific novelty of the study lies in applying the mental space theory to the process of allusion interpretation based on the text of a XIX-century English essay. As a result of the study, it has been determined that methods of conceptual integration can be effectively used in allusion interpretation.
Content of the TREUE Concept in German Linguoculture
Authors: Khlopova Anna Igorevna , Sidorova Victoria Pavlovna
Published: October 2022

The aim of the research is to identify trends and dynamics of the content of the TREUE concept. Scientific novelty of the research lies in conducting a comprehensive study of the concept, comparing experimental data of a free associative experiment and data from the German language corpus DWDS. The research findings have shown that the content of the TREUE concept changes dramatically. Represented by lexical units with a positive connotation in the nominative field and in the associative field of 2019, the content of the concept under study acquires properties with a negative connotation in the associative field of 2021. Respondents associate fidelity with the fear of losing a loved one, think about the consequences of infidelity.
Obligatory Components of the “Academic Mobility” Frame
Authors: Vishnevskaya Yuniya Igorevna
Published: October 2022

The study aims to identify features of the functioning of obligatory components in the space of the “academic mobility” frame. The paper sheds light on the linguistic features of the “academic mobility” frame, using texts presented on the websites of Russian universities. Scientific novelty of the work lies in the fact that it considers the notion of “academic mobility” as a frame; in addition, the study is the first to identify actants of this frame. Structural and content components for prototype frames and instance frames are proposed for the study. As a result of the study, obligatory semantic actants have been identified, their role in representation of the “academic mobility” frame has been determined.