bluuebunny/crossref_metadata_2025 huggingface dataset:
Biomimetic Silica Particles with Self-Loading BMP-2 Knuckle Epitope Peptide and Its Delivery for Bone Regeneration
Authors: Ki Mi-Ran , Nguyen Thi Khoa My , Park Tae-In , Park Hae-Min , Pack Seung Pil
Published: March 2023

Biomimetic silica deposition is an in-situ immobilization method for bioactive molecules under biocompatible conditions. The osteoinductive P4 peptide derived from the knuckle epitope of bone morphogenetic protein (BMP), which binds to BMP receptor-II (BMPRII), has been newly found to contain silica formation ability. We found that the two lysine residues at the N-terminus of P4 played a vital role in silica deposition. The P4 peptide co-precipitated with silica during P4-mediated silicification, yielding P4/silica hybrid particles (P4@Si) with a high loading efficiency of 87%. P4 was released from P4@Si at a constant rate for over 250 h, representing a zero-order kinetic model. In flow cytometric analysis, P4@Si showed a 1.5-fold increase in the delivery capacity to MC3T3 E1 cells than the free form of P4. Furthermore, P4 was found anchored to hydroxyapatite (HA) through a hexa-glutamate tag, followed by P4-mediated silicification, yielding P4@Si coated HA. This suggested a superior osteoinductive potential compared to silica or P4 alone coated HA in the in vitro study. In conclusion, the co-delivery of the osteoinductive P4 peptide and silica by P4-mediated silica deposition is an efficient method for capturing and delivering its molecules and inducing synergistic osteogenesis.
The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
Authors: Vorstandlechner Vera , Copic Dragan , Klas Katharina , Direder Martin , Golabi Bahar , Radtke Christine , Ankersmit Hendrik J. , Mildner Michael
Published: March 2023

Hypertrophic scars can cause pain, movement restrictions, and reduction in the quality of life. Despite numerous options to treat hypertrophic scarring, efficient therapies are still scarce, and cellular mechanisms are not well understood. Factors secreted by peripheral blood mononuclear cells (PBMCsec) have been previously described for their beneficial effects on tissue regeneration. In this study, we investigated the effects of PBMCsec on skin scarring in mouse models and human scar explant cultures at single-cell resolution (scRNAseq). Mouse wounds and scars, and human mature scars were treated with PBMCsec intradermally and topically. The topical and intradermal application of PBMCsec regulated the expression of various genes involved in pro-fibrotic processes and tissue remodeling. We identified elastin as a common linchpin of anti-fibrotic action in both mouse and human scars. In vitro, we found that PBMCsec prevents TGFβ-mediated myofibroblast differentiation and attenuates abundant elastin expression with non-canonical signaling inhibition. Furthermore, the TGFβ-induced breakdown of elastic fibers was strongly inhibited by the addition of PBMCsec. In conclusion, we conducted an extensive study with multiple experimental approaches and ample scRNAseq data demonstrating the anti-fibrotic effect of PBMCsec on cutaneous scars in mouse and human experimental settings. These findings point at PBMCsec as a novel therapeutic option to treat skin scarring.
Newly Synthesized Lignin Microparticles as Bioinspired Oral Drug-Delivery Vehicles: Flavonoid-Carrier Potential and In Vitro Radical-Scavenging Activity
Authors: Ivanova Donika , Toneva Monika , Simeonov Evgeni , Nikolova Biliana , Semkova Severina , Antov Georgi , Yaneva Zvezdelina
Published: March 2023

The aim of the present study was to synthesize lignin microparticles, to evaluate their physicochemical, spectral, morphological and structural characteristics, to examine their encapsulation and in vitro release potential and behaviour towards the flavonoid morin in simulated physiological medium and to assess the in vitro radical-scavenging potential of the morin-loaded lignin microcarrier systems. The physicochemical, structural and morphological characteristics of alkali lignin, lignin particles (LP) and morin-encapsulated lignin microparticles (LMP) were determined based on particle size distribution, SEM, UV/Vis spectrophotometric, FTIR and potentiometric titration analyses. The encapsulation efficiency of LMP was 98.1%. The FTIR analyses proved that morin was successfully encapsulated in the LP without unexpected chemical reactions between the flavonoid and the heteropolymer. The in vitro release performance of the microcarrier system was successfully mathematically described by Korsmeyer–Peppas and the sigmoidal models outlining the general role of diffusion during the initial stages of the in vitro release process in simulated gastric fluid (SGF), and the predominant contribution of biopolymer relaxation and erosion was determined in simulated intestinal medium (SIF). The higher radical-scavenging potential of LMP, as compared to that of LP, was proven via DPPH and ABTS assays. The synthesis of lignin microcarriers not only provides a facile approach for the utilization of the heteropolymer but also determines its potential for the design of drug-delivery matrices.
Physicochemical, Pre-Clinical, and Biological Evaluation of Viscosity Optimized Sodium Iodide-Incorporated Paste
Authors: Chang Soo-Jin , Kim Yu-Jin , Vu Huong Thu , Choi Ji-Myung , Park Jeong-Hui , Shin Seong-Jin , Dashnyam Khandmaa , Knowles Jonathan C. , Lee Hae-Hyoung , Jun Soo-Kyung , Han Mi-Ran , Lee Joon-Haeng , Kim Jong-Soo , Shin Ji-Sun , Kim Jong-Bin , Lee Jung-Hwan
Published: March 2023

This study aimed to investigate the impact of different viscosities of silicone oil on the physicochemical, pre-clinical usability, and biological properties of a sodium iodide paste. Six different paste groups were created by mixing therapeutic molecules, sodium iodide (D30) and iodoform (I30), with calcium hydroxide and one of the three different viscosities of silicone oil (high (H), medium (M), and low (L)). The study evaluated the performance of these groups, including I30H, I30M, I30L, D30H, D30M, and D30L, using multiple parameters such as flow, film thickness, pH, viscosity, and injectability, with statistical analysis (p < 0.05). Remarkably, the D30L group demonstrated superior outcomes compared to the conventional iodoform counterpart, including a significant reduction in osteoclast formation, as examined through TRAP, c-FOS, NFATc1, and Cathepsin K (p < 0.05). Additionally, mRNA sequencing showed that the I30L group exhibited increased expression of inflammatory genes with upregulated cytokines compared to the D30L group. These findings suggest that the optimized viscosity of the sodium iodide paste (D30L) may lead to clinically favorable outcomes, such as slower root resorption, when used in primary teeth. Overall, the results of this study suggest that the D30L group shows the most satisfactory outcomes, which may be a promising root-filling material that could replace conventional iodoform-based pastes.
Confocal Raman Spectroscopy for Assessing Bioequivalence of Topical Formulations
Authors: Iliopoulos Fotis , Tang Chun Fung , Li Ziyue , Rahma Annisa , Lane Majella E.
Published: March 2023

The evaluation of bioequivalence (BE) for topical dermatological drug products is challenging, and there has been significant interest from regulatory authorities in developing new BE methodologies in recent years. Currently, BE is demonstrated by comparative clinical endpoint studies; these are costly and time-consuming and often lack sensitivity and reproducibility. Previously, we reported excellent correlations between in vivo Confocal Raman Spectroscopy in human subjects and in vitro skin permeation testing (IVPT) with the human epidermis for skin delivery of ibuprofen and a number of excipients. The aim of the present proof-of-concept study was to evaluate CRS as a method to assess BE of topical products. Two commercially available formulations, Nurofen Max Strength 10% Gel and Ibuleve Speed Relief Max Strength 10% Gel, were selected for evaluation. Delivery of ibuprofen (IBU) to the skin was determined in vitro and in vivo by IVPT and CRS, respectively. The formulations examined were found to deliver comparable amounts of IBU across the skin over 24 h in vitro (p > 0.05). Additionally, the formulations resulted in similar skin uptake values measured with CRS in vivo, either at 1 h or 2 h after application (p > 0.05). This is the first study to report the capability of CRS for the demonstration of BE of dermal products. Future studies will focus on the standardisation of the CRS methodology for a robust and reproducible pharmacokinetic (PK)-based evaluation of topical BE.
Estimation of Pediatric Dosage of Antimalarial Drugs, Using Pharmacokinetic and Physiological Approach
Authors: Mhango Ellen K. G. , Snorradottir Bergthora S. , Kachingwe Baxter H. K. , Katundu Kondwani G. H. , Gizurarson Sveinbjorn
Published: March 2023

Most of the individuals who die of malaria in sub–Saharan Africa are children. It is, therefore, important for this age group to have access to the right treatment and correct dose. Artemether—lumefantrine is one of the fixed dose combination therapies that was approved by the World Health Organization to treat malaria. However, the current recommended dose has been reported to cause underexposure or overexposure in some children. The aim of this article was, therefore, to estimate the doses that can mimic adult exposure. The availability of more and reliable pharmacokinetic data is essential to accurately estimate appropriate dosage regimens. The doses in this study were estimated using the physiological information from children and some pharmacokinetic data from adults due to the lack of pediatric pharmacokinetic data in the literature. Depending on the approach that was used to calculate the dose, the results showed that some children were underexposed, and others were overexposed. This can lead to treatment failure, toxicity, and even death. Therefore, when designing a dosage regimen, it is important to know and include the distinctions in physiology at various phases of development that influence the pharmacokinetics of various drugs in order to estimate the dose in young children. The physiology at each time point during the growth of a child may influence how the drug is absorbed, gets distributed, metabolized, and eliminated. From the results, there is a very clear need to conduct a clinical study to further verify if the suggested (i.e., 0.34 mg/kg for artemether and 6 mg/kg for lumefantrine) doses could be clinically efficacious.
Taking Natural History Seriously: Whitehead and Merleau-Ponty’s Ontological Approach
Authors: Brioschi Maria Regina
Published: March 2023

This paper investigates Alfred North Whitehead and Maurice Merleau-Ponty’s attempts to develop a historical, dynamic ontology (a “process ontology”, according to the former, and an “ontology of the flesh” for the latter). The claim of the paper is that their originality lies in the methods adopted to reach such ontologies, which show strong similarities. Both authors based their research on nature, conceived of as “the leaf of Being”, and on perceptual experience, understood not as a chaos of bare, punctual, sense data, but as the complex, original source of meaning that constitutes the primary field of philosophical investigation—the only source from which one can gain new understanding of both nature and logos (things, happenings, values, subjectivity, laws, etc.). After some introductory remarks on the connections between Whitehead and Merleau-Ponty, the paper is divided into three parts. The first part clarifies why and how, according to the philosophers, ontology should start from a new scrutiny of nature. The second part specifies what this new conception of nature, based on perceptual experience, is. The third part focuses on how their ontologies must be construed as historic, insofar as behaviors, actions, and practices lie at the core of their concept of being.
Lines of Quasi-BICs and Butterworth Line Shape in Stacked Resonant Gratings: Analytical Description
Authors: Golovastikov Nikita V. , Bykov Dmitry A. , Bezus Evgeni A. , Doskolovich Leonid L.
Published: March 2023

We propose analytical approximations of the reflection and transmission spectra of a stacked dielectric diffraction grating consisting of two identical resonant guided-mode gratings with a Lorentzian line shape. These approximations, derived using the scattering matrix formalism, are functions of both angular frequency ω and the tangential wave vector component kx of the incident wave. We analytically demonstrate and, using full-wave simulations with rigorous coupled-wave analysis technique, numerically confirm that by a proper choice of the thickness of the dielectric layer separating the gratings, one can tailor the resonant optical properties of the stacked structure. In particular, it is possible to obtain lines of quasi-bound states in the continuum in the ω–kx parameter space with the quality factor decaying proportionally to kx−4 or kx−6. In addition, the stacked structure can be used as a spectral or spatial Butterworth filter operating in reflection. The presented results may find application in the design of optical filters and sensors based on stacked resonant gratings.
Generation, Topological Charge, and Orbital Angular Momentum of Off-Axis Double Vortex Beams
Authors: Guo Mingxian , Le Wei , Wang Chao , Rui Guanghao , Zhu Zhuqing , He Jun , Gu Bing
Published: March 2023

Compared with the on-axis vortex beam and the off-axis single vortex beam, the off-axis double vortex beam has more control degrees of freedom and brings rich physical properties. In this work, we investigate theoretically and experimentally the generation, topological charge (TC), and orbital angular momentum (OAM) of off-axis double vortex beams. It is demonstrated that the tilted lens method can detect not only the magnitudes and signs of two TCs of the off-axis double vortex beam but also the spatial distribution of the TCs. Moreover, the average OAM value of the off-axis double vortex beam decreases nonlinearly as the off-axis distance increases, although its TC is independent of the off-axis distance of phase singularities. The results indicate that the average OAM of the off-axis double vortex beam can be easily controlled by changing the relative position of two-phase singularities, thereby realizing the applications of multi-degrees of freedom particle manipulation, optical communication, and material processing.
Effect of Pulsation in Microstructure and Mechanical Properties of Titanium Alloy-Annealed Welded Joints at Different Temperatures
Authors: Kumar Uday , Chattopadhyaya Somnath , Das Alok Kumar , Seikh A. H. , Sharma Shubham , Dwivedi Shashi Prakash , Nagai Kaori , Kumar Abhinav , Agrawal Ashish , Singh Sunpreet
Published: March 2023

Thin sheets of Ti-6Al-4V alloy of thickness 1 mm were butt welded using a pulsed Nd-YAG low-power laser setup. The goal of this research is to explore the influence of pulsation on the microstructure and mechanical properties. In addition to that, annealing at different temperatures has been performed to compare the results of pulsation and heat treatment. The results indicate that after annealing at 980 °C, the structure completely transformed into an equiaxed structure. When annealed at 1010 °C, almost the total area is composed of an equiaxed α phase, and the grains are coarse as compared to the previous. This suggests that the grain size becomes thicker when the annealing temperature is raised above 980 °C. The volume fraction of the equiaxed structure is maximum. It can be deduced that the volume–fraction is dependent on the annealing temperature. The volume fraction of the equiaxed structure increases as the annealing temperature increases. A higher tensile strength value of the sample annealed at 980 °C was found as compared with the overlapped sample (A-2). The fusion zone overlapped sample (A-2) shows high hardness with a value of 397 HV1. In the FZ sample, annealing at 980 °C has a hardness of 386 HV1. The (A-2) sample indicates higher (3–4%) hardness as compared to the annealed sample at the FZ. The β phase is increased by 16% in the XRD analysis of the overlapped samples. Hence, it is evident that the amount of β phase has increased during heating, and a complete transformation has taken place at a temperature of 958 °C.
Moisture Sorption Isotherms and Thermodynamic Properties of Biodegradable Polymers for Application in Food Packaging Industry
Authors: Tavares Loleny , Sousa Liliana R. , Magalhães da Silva Sara , Lima Paulo S. , Oliveira J. M.
Published: March 2023

This work aims to evaluate the influence of two starch-based materials (B16 and B20) on the moisture sorption isotherms, determined at 30, 40, and 50 °C, where B16 contains 5% (w/w) more starch than B20. Thermodynamic functions (differential enthalpy (∆Hdif), differential entropy (∆Sdif), integral enthalpy (Δhint), integral entropy (ΔSint), free Gibbs energy (∆G), and spreading pressure (φ)) were used to understand the water-binding behaviors and the energy requirements to remove the moisture content from the surface of these materials. The moisture sorption isotherms exhibited type III behavior, and the Guggenheim–Anderson–de Boer (GAB) model was the most suitable to fit the experimental moisture adsorption data. The adsorption isotherms of microparticles were enthalpy-controlled, with isokinetic temperature values of 221.45 and 279.77 K for B16 and B20, respectively, being higher than the harmonic mean temperature (312.94 K). The values of ∆G were positive (45.274 and 44.307 kJmol−1 for B16 and B20, respectively), indicating a non-spontaneous process. The spreading pressure values increased with increasing water activity (aw) for all isotherms. Higher values of ∆Hdif and ∆Sdif obtained from B16 confirmed its higher number of sorption sites available for binding with water molecules when compared to B20, making it less suitable for application in the food packaging industry.
Determination of Hyaluronic Acid Dermal Filler Impurities Using SEM/EDS Analysis
Authors: Lee Won , Rho Nark-Kyoung , Yang Eun-Jung
Published: March 2023

Although hyaluronic acid (HA) filler injections are associated with various non-vascular inflammatory complications, the underlying mode of action remains unclear. The hyaluronic acid filler may not be sufficiently pure, leading to an immune response. The present study attempted to identify any impurities in hyaluronic acid fillers available on the market. Particles were counted after degrading hyaluronic acid filler with hyaluronidase. Particulate matter was subsequently observed using scanning electron microscopy, and the particle components were evaluated using energy-dispersive X-ray spectroscopy. Different quantities of impurity particles (>10 and 25 μm) were detected microscopically. Silicon and aluminum isotopes were also detected. Hyaluronic acid fillers were contaminated with these particles. The degree of contamination varied substantially among the tested filler products. These contaminant particles may evoke reactions in the patient’s body. Clinicians should be aware of this source of possible contamination and its effects.
Examination of Low-Cyclic Fatigue Tests and Poisson’s Ratio Depending on the Different Infill Density of Polylactide (PLA) Produced by the Fused Deposition Modeling Method
Authors: Gaweł Anna , Kuciel Stanisław , Liber-Kneć Aneta , Mierzwiński Dariusz
Published: March 2023

This article examines the impact of fatigue cycles on polylactide samples produced by 3D printing using the FDM method. Samples were printed in three infill degree variants: 50%, 75% and 100%. To compere the influence of infill degree on PLA properties, several tests, including the uniaxial tensile test, the low-cycle fatigue test, differential scanning calorimetry (DSC) and scanning electron microscopy (SEM), were conducted. Poisson’s ratio has also been studied. Single hysteresis loops were summed to obtain the entire low-fatigue cycle. The infill of density influenced all compared mechanical parameters. The decrease in infill degree caused the reduction of Young’s modulus and shear modulus. For a 100% degree of sample infill, a higher number of transferred load cycles were observed compared to PLA with 75% and 50% of infill. Additionally, the value of the transferred cyclic load before fatigue failure and the dissipation of mechanical energy was the highest for 100% of infill. It is also worth noting that fatigue tests can positively affect the appearance of the PLA structure. Obviously, it depends on the number of load cycles and the infill density. It causes that if the goal is to transfer as much load as possible over a long period of time, the maximum filling of the printed element should be used.
Electrospun Materials Based on Polymer and Biopolymer Blends—A Review
Authors: Tahir Muhammad , Vicini Silvia , Sionkowska Alina
Published: March 2023

This review covers recent developments and progress in polymer and biopolymer blending and material preparation by electrospinning. Electrospinning is a technique that is used to produce nanofibers to improve the quality of membranes. Electrospun nanofibers are highly applicable in biomedical sciences, supercapacitors, and in water treatment following metal ion adsorption. The key affecting factors of electrospinning have been checked in the literature to obtain optimal conditions of the electrospinning process. Future research directions and outlooks have been suggested to think about innovative ideas for research in this field.
Flame Retardancy of Epoxy Resins Modified with Few-Layer Black Phosphorus
Authors: Zhao Yongzheng , Li Yan , Li Jiaxuan , Xiao Yifan , Mu Wenmin , Wang Zhongwei , Song Liang , Yu Jinhong
Published: March 2023

Few-layer black phosphorus (BP)- and red phosphorus (RP)-modified diglycidyl ether of bisphenol A-based epoxy resins (EP) was prepared with 4,4′-diaminodiphenylsulfone as a curing agent. The thermal stability and flame-retardant properties of the modified EPs were compared. Both BP and RP were able to improve the flame-retardant properties of EPs, while the BP showed higher flame-retardant efficiency than RP. As a two-dimensional nanomaterial, BP exhibited good compatibility, high flame-retardant efficiency, and negligible impact on the mechanical and thermal stability of EP. Pyrolysis-gas Fourier-transform infrared spectroscopic analysis of EP showed that the addition of BP significantly inhibited the release of pyrolysis products in the gas phase. The modes of action for flame-retardant BPs in gas phase and condensed phase were proposed.
Effect of Formation Pressure on Pore Structure Evolution and Hydrocarbon Expulsion in Organic-Rich Marine Shale
Authors: Fang Xianglong , Cai Yidong , Hu Qinhong , Gao Ping , Liu Dameng , Qian Yujing
Published: March 2023

Exploring the relationship between formation pressure and shale pore evolution is helpful for the enrichment and development of marine shale gas accumulation theory. The thermal evolution experiment was carried out on the Xiamaling Formation (Pr3x) lowly matured marine shale, which has a similar sedimentary environment to the Longmaxi Formation (S1l) highly matured marine shale. Comparative experiments of open and semi-closed pyrolysis and multiple pore structure characterization techniques, including CO2 and N2 physisorption, mercury intrusion porosimetry, and field emission scanning electron microscopy, were conducted. The marine shale pore evolutionary model under formation pressure is proposed by characterizing pore evolution, and hydrocarbon expulsion and retention for shales under and without formation fluid pressures. The results show that the existence of formation pressure increases the percentage of quartz and reduces the content of clay minerals. The change in formation pressure has no obvious effect on the maturity evolution of shale samples. With the increase of formation pressure, the pore morphology of shale gradually changes from narrow slit pores to ink bottle-shaped pores. The retained hydrocarbons in shale mainly occupy the mesopore space, and the existence of formation pressure promotes hydrocarbon expulsion, especially the hydrocarbon expulsion in the mesopore. In addition, formation pressure improves pore connectivity, especially in the high-over mature stage of shale. With the increase of formation pressure, the micropore volume decreases slightly, the mesopore volume increases significantly, and the macropore volume changes have two stages.
Hybrid Gold Open Access Citation Advantage in Clinical Medicine: Analysis of Hybrid Journals in the Web of Science
Authors: Saravudecha Chompunuch , Na Thungfai Duangruthai , Phasom Chananthida , Gunta-in Sodsri , Metha Aorrakanya , Punyaphet Peangkobfah , Sookruay Tippawan , Sakuludomkan Wannachai , Koonrungsesomboon Nut
Published: March 2023

Biomedical fields have seen a remarkable increase in hybrid Gold open access articles. However, it is uncertain whether the hybrid Gold open access option contributes to a citation advantage, an increase in the citations of articles made immediately available as open access regardless of the article’s quality or whether it involves a trending topic of discussion. This study aimed to compare the citation counts of hybrid Gold open access articles to subscription articles published in hybrid journals. The study aimed to ascertain if hybrid Gold open access publications yield an advantage in terms of citations. This cross-sectional study included the list of hybrid journals under 59 categories in the ‘Clinical Medicine’ group from Clarivate’s Journal Citation Reports (JCR) during 2018–2021. The number of citable items with ‘Gold Open Access’ and ‘Subscription and Free to Read’ in each journal, as well as the number of citations of those citable items, were extracted from JCR. A hybrid Gold open access citation advantage was computed by dividing the number of citations per citable item with hybrid Gold open access by the number of citations per citable item with a subscription. A total of 498, 636, 1009, and 1328 hybrid journals in the 2018 JCR, 2019 JCR, 2020 JCR, and 2021 JCR, respectively, were included in this study. The citation advantage of hybrid Gold open access articles over subscription articles in 2018 was 1.45 (95% confidence interval (CI), 1.24–1.65); in 2019, it was 1.31 (95% CI, 1.20–1.41); in 2020, it was 1.30 (95% CI, 1.20–1.39); and in 2021, it was 1.31 (95% CI, 1.20–1.42). In the ‘Clinical Medicine’ discipline, the articles published in the hybrid journal as hybrid Gold open access had a greater number of citations when compared to those published as a subscription, self-archived, or otherwise openly accessible option.
HY1C/D-CZI Noctiluca scintillans Bloom Recognition Network Based on Hybrid Convolution and Self-Attention
Authors: Cui Hanlin , Chen Shuguo , Hu Lianbo , Wang Junwei , Cai Haobin , Ma Chaofei , Liu Jianqiang , Zou Bin
Published: March 2023

Accurate Noctiluca scintillans bloom (NSB) recognition from space is of great significance for marine ecological monitoring and underwater target detection. However, most existing NSB recognition models require expert visual interpretation or manual adjustment of model thresholds, which limits model application in operational NSB monitoring. To address these problems, we developed a Noctiluca scintillans Bloom Recognition Network (NSBRNet) incorporating an Inception Conv Block (ICB) and a Swin Attention Block (SAB) based on the latest deep learning technology, where ICB uses convolution to extract channel and local detail features, and SAB uses self-attention to extract global spatial features. The model was applied to Coastal Zone Imager (CZI) data onboard Chinese ocean color satellites (HY1C/D). The results show that NSBRNet can automatically identify NSB using CZI data. Compared with other common semantic segmentation models, NSBRNet showed better performance with a precision of 92.22%, recall of 88.20%, F1-score of 90.10%, and IOU of 82.18%.
Spatial Visualization Based on Geodata Fusion Using an Autonomous Unmanned Vessel
Authors: Włodarczyk-Sielicka Marta , Połap Dawid , Prokop Katarzyna , Połap Karolina , Stateczny Andrzej
Published: March 2023

The visualization of riverbeds and surface facilities on the banks is crucial for systems that analyze conditions, safety, and changes in this environment. Hence, in this paper, we propose collecting, and processing data from a variety of sensors—sonar, LiDAR, multibeam echosounder (MBES), and camera—to create a visualization for further analysis. For this purpose, we took measurements from sensors installed on an autonomous, unmanned hydrographic vessel, and then proposed a data fusion mechanism, to create a visualization using modules under and above the water. A fusion contains key-point analysis on classic images and sonars, augmentation/reduction of point clouds, fitting data and mesh creation. Then, we also propose an analysis module that can be used to compare and extract information from created visualizations. The analysis module is based on artificial intelligence tools for the classification tasks, which helps in further comparison to archival data. Such a model was tested using various techniques to achieve the fastest and most accurate visualizations possible in simulation and real case studies.
Joint Estimation of Ground Displacement and Atmospheric Model Parameters in Ground-Based Radar
Authors: Zhu Yan , Xu Bing , Li Zhiwei , Li Jie , Hou Jingxin , Mao Wenxiang
Published: March 2023

Atmospheric delay is the primary error in ground-based synthetic aperture radar (GBSAR). The existing compensation methods include the external meteorological data correction method, the polynomial fitting method, and the persistent scatterers SAR interferometry (PSInSAR) calibration method. Combining the polynomial fitting and the persistent scatterers targets is the most popular method of GBSAR atmospheric delay compensation. However, the displacement component of the coherent target is always ignored in the atmospheric delay compensation, which is unpractical. A joint estimation method of ground displacement and atmospheric model parameters is developed in this paper. The displacement component is determined by the spatial and temporal features of the objects. The atmospheric delay component is regarded as a systematic error represented by a quadratic polynomial related to distance. The result is resolved by the least-square method. Compared to the existing method, the root-mean-square error (RMSE) of the proposed method had a significant improvement in the validation experiment. In the real in situ experiment, the time series obtained by the GBSAR had a similar trend to that acquired by the Global Positioning System (GPS) receiver. It is indicated that the proposed method can lead to a better deformation estimation by taking the deformation component into account in the atmospheric compensation.
Monitoring of Land Degradation in Greece and Tunisia Using Trends.Earth with a Focus on Cereal Croplands
Authors: Cherif Ines , Kolintziki Eleni , Alexandridis Thomas K.
Published: March 2023

Land degradation (LD) processes are widespread in drylands worldwide and are accelerated by climate change. As a result, food security and livelihoods are at risk. Thus, there is a need to monitor LD trends, especially in agricultural areas. Mediterranean countries, including Tunisia and Greece, are concerned due to the presence of drivers and pressures causing land degradation. Through the Trends.Earth plugin, the SDG 15.3.1 indicator can be implemented to map LD status. In this study, we mapped LD in Greece and Tunisia for the recommended baseline period of 2001–2015 and the selected reporting period of 2016–2020. The land productivity was assessed within Trends.Earth using the MODIS MOD13Q1 product, while the default datasets were used for the other sub-indicators. The main findings are: (i) the percentage of degraded land decreased from the baseline to the reporting period from 4.83% to 2.62% of total area in Greece and 9.97% to 6.26% in Tunisia—degradation rates that differ from those reported to the UNCCD (United Nations Convention to Combat Desertification) by the respective national authorities; (ii) the dominant land condition in Greece was improved, while in Tunisia, it was stable; (iii) land productivity presented a similar trend through the SDG 15.3.1 indicator over both countries, including the net land productivity dynamics over croplands; (iv) based on analysis using plant functional types performed with MODIS MCD12Q1, the highest portion of degraded land in Greece was located in grasslands and in Tunisia in cereal croplands (after desert areas); and (v) with a focus on LD over cereal croplands, the portion of degraded areas appeared to decrease in both Greece and Tunisia. The percentage was higher in Tunisia, representing 16.52% of the total degraded land during the reporting period compared to 10.83% in Greece. All the above stress the need to foster the adoption of sustainable land management practices, especially in Tunisia, and speed up the implementation of measures to achieve LD neutrality.
A Dynamic Effective Class Balanced Approach for Remote Sensing Imagery Semantic Segmentation of Imbalanced Data
Authors: Zhou Zheng , Zheng Change , Liu Xiaodong , Tian Ye , Chen Xiaoyi , Chen Xuexue , Dong Zixun
Published: March 2023

The wide application and rapid development of satellite remote sensing technology have put higher requirements on remote sensing image segmentation methods. Because of its characteristics of large image size, large data volume, and complex segmentation background, not only are the traditional image segmentation methods difficult to apply effectively, but the image segmentation methods based on deep learning are faced with the problem of extremely unbalanced data between categories. In order to solve this problem, first of all, according to the existing effective sample theory, the effective sample calculation method in the context of semantic segmentation is firstly proposed in the highly unbalanced dataset. Then, a dynamic weighting method based on the effective sample concept is proposed, which can be applied to the semantic segmentation of remote sensing images. Finally, the applicability of this method to different loss functions and different network structures is verified on the self-built Landsat8-OLI remote sensing image-based tri-classified forest fire burning area dataset and the LoveDA dataset, which is for land-cover semantic segmentation. It has been concluded that this weighting algorithm can enhance the minimal-class segmentation accuracy while ensuring that the overall segmentation performance in multi-class segmentation tasks is verified in two different semantic segmentation tasks, including the land use and land cover (LULC) and the forest fire burning area segmentation In addition, this proposed method significantly improves the recall of forest fire burning area segmentation by as much as about 30%, which is of great reference value for forest fire research based on remote sensing images.
Assessing the Impact of Land Use and Land Cover Changes on Aflaj Systems over a 36-Year Period
Authors: Al-Kindi Khalifa M. , Alqurashi Abdullah F. , Al-Ghafri Abdullah , Power Dennis
Published: March 2023

The aflaj systems represent unique irrigation technologies that have been implemented in the Sultanate of Oman. This innovative system, referred to as “falaj” in the singular form, is composed of a sophisticated network of underground tunnels and open-air channels designed to access shallow subterranean water tables, thereby providing water for residential and agricultural use. The aflaj systems have played a significant role in supporting sustainable water resource management in arid and semiarid regions, making a notable contribution to the socioeconomic development of the country. The alteration of land use and land cover (LULC) in arid and semiarid regions can have significant consequences for hydrological systems, affecting the ability of local ecosystems to manage fresh surface and groundwater resources. These changes are often caused by both natural and anthropogenic factors. To investigate the impact of LULC changes on aflaj systems in the northern part of Oman, we utilized satellite imagery, aflaj data, and spatial analytical and image processing techniques within the framework of geographic information systems (GIS) and remote sensing. In the first part of the study, we quantified the changes in LULC and their impact on aflaj systems in seven cities in Oman due to urban expansion. In the second part, we evaluated the effect of LULC on groundwater for four major aflaj between 1985 and 2021. The study area was divided into four primary LULC classifications: vegetation, bodies of water, metropolitan areas, and bare soil. The classification maps demonstrated a high overall accuracy of 90% to 95%, indicating satisfactory performance. Our results revealed a significant reduction in vegetation areas between 1985 and 2021, primarily shifting from bare soil (BS) to urban areas (UAs) and from vegetation cover (VC) to BS, due to the reduction of groundwater resources. Over the four study periods (1985–1990, 1990–2000, 2000–2013, and 2013–2021), the percentages of the total area of Falaj Al-Muyasser, Falaj Daris, Falaj Al-Maliki, and Falaj Al-Khatmeen that transformed from agricultural lands to UAs were 40%, 39%, 32%, and 8%, respectively. Our study highlights the need for appropriate land management and planning to ensure the most effective solutions are utilized to meet social and economic sustainability requirements. In conclusion, our study presents a comprehensive analysis of LULC changes and their impact on aflaj systems over a 36-year period, providing new insights into the potential effects of LULC changes on groundwater resources and offering a basis for informed decision making on land management in arid and semiarid areas.
Extended Cross-Calibration Analysis Using Data from the Landsat 8 and 9 Underfly Event
Authors: Gross Garrison , Helder Dennis , Leigh Larry
Published: March 2023

The Landsat 8 and 9 Underfly Event occurred in November 2021, during which Landsat 9 flew beneath Landsat 8 in the final stages before settling in its final orbiting path. An analysis was performed on the images taken during this event, which resulted in a cross-calibration with uncertainties estimated to be less than 0.5%. This level of precision was due, in part, to the near-identical sensors aboard each instrument, as well as the underfly event itself, which allowed the sensors to take nearly the exact same image at nearly the exact same time. This initial calibration was applied before the end of the on-orbit initial verification (OIV) period; this meant the analysis was performed in less than a month. While it was an effective and efficient first look at the data, a longer-term analysis was deemed prudent to obtain the most accurate cross-calibration with the smallest uncertainties. The three forms of uncertainty established in the initial analysis, dubbed “Phase 1”, were geometric, spectral, and angular. This paper covers Phase 2 of the underfly analysis; several modifications were made to the Phase 1 process to improve the cross-calibration results, including a spectral correction in the form of a spectral band adjustment factor (SBAF) and a more robust filtering system that used the statistics of the reflectance data to better include important data compared to the more aggressive filters used in Phase 1. A proper uncertainty analysis was performed to more accurately quantify the uncertainty associated with the underfly cross-calibration. The results of Phase 2 showed that the Phase 1 analysis was within its 0.5% uncertainty estimation, and the cross-calibration gain values in this paper were used by USGS EROS to update the Landsat 9 calibration at the end of 2022.
Scheduling Framework for Accelerating Multiple Detection-Free Object Trackers
Authors: Kim Myungsun , Kim Inmo , Yong Jihyeon , Kim Hyuksoo
Published: March 2023

In detection-free tracking, after users freely designate the location of the object to be tracked in the first frame of the video sequence, the location of the object is continuously found in the following video frame sequence. Recently, technologies using a Siamese network and transformer based on DNN modules have been evaluated as very excellent in terms of tracking accuracy. The high computational complexity due to the usage of the DNN module is not a preferred feature in terms of execution speed, and when tracking two or more objects, a bottleneck effect occurs in the DNN accelerator such as the GPU, which inevitably results in a larger delay. To address this problem, we propose a tracker scheduling framework. First, the computation structures of representative trackers are analyzed, and the scheduling unit suitable for the execution characteristics of each tracker is derived. Based on this analysis, the decomposed workloads of trackers are multi-threaded under the control of the scheduling framework. CPU-side multi-threading leads the GPU to a work-conserving state while enabling parallel processing as much as possible even within a single GPU depending on the resource availability of the internal hardware. The proposed framework is a general-purpose system-level software solution that can be applied not only to GPUs but also to other hardware accelerators. As a result of confirmation through various experiments, when tracking two objects, the execution speed was improved by up to 55% while maintaining almost the same accuracy as the existing method.
Advances in Multicore Fiber Interferometric Sensors
Authors: Yao Yucheng , Zhao Zhiyong , Tang Ming
Published: March 2023

In this paper, a review of multicore fiber interferometric sensors is given. Due to the specificity of fiber structure, i.e., multiple cores integrated into only one fiber cladding, multicore fiber (MCF) interferometric sensors exhibit many desirable characteristics compared with traditional fiber interferometric sensors based on single-core fibers, such as structural and functional diversity, high integration, space-division multiplexing capacity, etc. Thanks to the unique advantages, e.g., simple fabrication, compact size, and good robustness, MCF interferometric sensors have been developed to measure various physical and chemical parameters such as temperature, strain, curvature, refractive index, vibration, flow, torsion, etc., among which the extraordinary vector-bending sensing has also been extensively studied by making use of the differential responses between different cores of MCFs. In this paper, different types of MCF interferometric sensors and recent developments are comprehensively reviewed. The basic configurations and operating principles are introduced for each interferometric structure, and, eventually, the performances of various MCF interferometric sensors for different applications are compared, including curvature sensing, vibration sensing, temperature sensing, and refractive index sensing.
Evaluating Synthetic Medical Images Using Artificial Intelligence with the GAN Algorithm
Authors: Abdusalomov Akmalbek Bobomirzaevich , Nasimov Rashid , Nasimova Nigorakhon , Muminov Bahodir , Whangbo Taeg Keun
Published: March 2023

In recent years, considerable work has been conducted on the development of synthetic medical images, but there are no satisfactory methods for evaluating their medical suitability. Existing methods mainly evaluate the quality of noise in the images, and the similarity of the images to the real images used to generate them. For this purpose, they use feature maps of images extracted in different ways or distribution of images set. Then, the proximity of synthetic images to the real set is evaluated using different distance metrics. However, it is not possible to determine whether only one synthetic image was generated repeatedly, or whether the synthetic set exactly repeats the training set. In addition, most evolution metrics take a lot of time to calculate. Taking these issues into account, we have proposed a method that can quantitatively and qualitatively evaluate synthetic images. This method is a combination of two methods, namely, FMD and CNN-based evaluation methods. The estimation methods were compared with the FID method, and it was found that the FMD method has a great advantage in terms of speed, while the CNN method has the ability to estimate more accurately. To evaluate the reliability of the methods, a dataset of different real images was checked.
An Access Control System Based on Blockchain with Zero-Knowledge Rollups in High-Traffic IoT Environments
Authors: Lin Xin , Zhang Yuanyuan , Huang Changhai , Xing Bin , Chen Liangyin , Hu Dasha , Chen Yanru
Published: March 2023

The access control (AC) system in an IoT (Internet of Things) context ensures that only authorized entities have access to specific devices and that the authorization procedure is based on pre-established rules. Recently, blockchain-based AC systems have gained attention within research as a potential solution to the single point of failure issue that centralized architectures may bring. Moreover, zero-knowledge proof (ZKP) technology is included in blockchain-based AC systems to address the issue of sensitive data leaking. However, current solutions have two problems: (1) systems built by these works are not adaptive to high-traffic IoT environments because of low transactions per second (TPS) and high latency; (2) these works cannot fully guarantee that all user behaviors are honest. In this work, we propose a blockchain-based AC system with zero-knowledge rollups to address the aforementioned issues. Our proposed system implements zero-knowledge rollups (ZK-rollups) of access control, where different AC authorization requests can be grouped into the same batch to generate a uniform ZKP, which is designed specifically to guarantee that participants can be trusted. In low-traffic environments, sufficient experiments show that the proposed system has the least AC authorization time cost compared to existing works. In high-traffic environments, we further prove that based on the ZK-rollups optimization, the proposed system can reduce the authorization time overhead by 86%. Furthermore, the security analysis is presented to show the system’s ability to prevent malicious behaviors.
“Grafting-To” Covalent Binding of Plasmonic Nanoparticles onto Silica WGM Microresonators: Mechanically Robust Single-Molecule Sensors and Determination of Activation Energies from Single-Particle Events
Authors: Serrano Mariana P. , Subramanian Sivaraman , von Bilderling Catalina , Rafti Matías , Vollmer Frank
Published: March 2023

We hereby present a novel “grafting-to”-like approach for the covalent attachment of plasmonic nanoparticles (PNPs) onto whispering gallery mode (WGM) silica microresonators. Mechanically stable optoplasmonic microresonators were employed for sensing single-particle and single-molecule interactions in real time, allowing for the differentiation between binding and non-binding events. An approximated value of the activation energy for the silanization reaction occurring during the “grafting-to” approach was obtained using the Arrhenius equation; the results agree with available values from both bulk experiments and ab initio calculations. The “grafting-to” method combined with the functionalization of the plasmonic nanoparticle with appropriate receptors, such as single-stranded DNA, provides a robust platform for probing specific single-molecule interactions under biologically relevant conditions.