bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship between Corporate Governance Quality and Firm Performance: The Moderating Role of Capital Structure
Authors: Mansour Marwan , Al Amosh Hamzeh , Alodat Ahmad Yuosef , Khatib Saleh F. A. , Saleh Mohammed W. A.
Published: August 2022

This study aims to explore whether capital structure (CS) has a contingent role in the relationship between corporate governance (CG) quality and firm performance. The empirical findings indicate that CG quality had a positive and significant effect on the performance of Jordanian non-financial firms listed on the Amman Stock Exchange (ASE) from 2014 to 2019. Additionally, the moderate effect of the CS reinforces this relationship. These results are robust to alternative econometric specifications and variable definitions. This study utilizes certain firm-specific characteristics to represent the CS to assess its role as a moderating variable in the relationship between CG quality and firm performance. This study makes a contribution to the literature by showing that CS can strengthen the relationship between CG quality and firm performance. The results have important managerial implications for the practice of CG in developing countries. Firms in developing countries can enhance performance by implementing and abiding by good governance practices. Moreover, firms in developing countries should adopt effective financial strategies regarding CS to enhance the relationship between CG quality and firm performance. Finally, potential investors should consider the debt level in the CS of non-financial firms in Jordan when making investment decisions.
Sustainability and the Social Representation of the COVID-19 Pandemic: A Missing Link
Authors: Joia Luiz Antonio , Michelotto Flavia , Lorenzo Manuela
Published: August 2022

The COVID-19 pandemic highlighted the importance for countries to preserve a sustainable health system. Unfortunately, the emergency nature of the COVID-19 pandemic has led to economic and social disasters, putting global health at risk. Thus, through the Social Representation Theory, our aim is to replicate a previous study carried out in Brazil in mid-2020 on how Brazilian society has perceived the significance of the COVID-19 pandemic in order to investigate whether this perception changed almost a year after the publication of the former study. The results show that the perception of Brazilian society about the COVID-19 pandemic in Brazil was, at the end of 2021, mainly shaped by the political polarization that existed at the time in the country. Thus, politics and government, social distancing, death, and fear were the categories that composed the central nucleus of the social representation of the COVID-19 pandemic. On the other hand, categories such as economy and employment and changes and the new normal were mentioned less. Surprisingly, the sustainability category was practically disregarded by Brazilians, thus constituting a missing link. In this way, with this research, we hope to contribute to a better understanding of this scenario, expanding the understanding of how society’s interpretation of the COVID-19 pandemic in an emerging country such as Brazil has changed over time. Finally, understanding the dynamics of society’s perception of the COVID-19 pandemic can contribute to better planning of local initiatives, both at a managerial and public levels, with the aim of mitigating this and other possible future pandemics in a sustainable way.
Commercial Fungicide Toxic Effects on Terrestrial Non-Target Species Might Be Underestimated When Based Solely on Active Ingredient Toxicity and Standard Earthworm Tests
Authors: Jorge-Escudero Gabriella , Pérez Polanco Mariana , Lagerlöf Jan Erland , Pérez Carlos Alberto , Míguez Diana
Published: August 2022

The ecosystem services provided by earthworms are lost when land management reduces their populations, hence, the importance of thorough assessments of management effects on this group. The present study aimed to: (1) review the possible influence of other ingredients within the formulations of two commercial fungicides; (2) assess the sublethal effects of these commercial fungicides on Eisenia fetida; and (3) assess the acute lethal effects of one commercial fungicide on both Glossoscolex rione and E. fetida. Examining all components of the studied commercial formulations revealed that alongside the toxic active ingredients are other ingredients that are equally as or more toxic than the former and may even be in higher concentrations. The inhibition concentration of 10% of E. fetida’s progeny (IC10) was estimated at 133 mg kg−1 for PROSARO® and 1544 mg kg−1 for SWING PLUS®. Both fungicides showed an effect of hormesis on the progeny. In this first toxicity study with G. rione, it was found that this species is more sensitive to PROSARO® than E. fetida, with preliminary 14 day-lethal concentrations of 285 mg kg−1 for the former and >1000 mg kg−1 for the latter.
Interannual and Decadal Changes in Harmful Algal Blooms in the Coastal Waters of Fujian, China
Authors: Zhang Caiyun
Published: August 2022

The temporal and spatial variability of harmful algal blooms (HABs) in coastal waters of Fujian were analyzed at interannual and decadal scales based on recorded HAB events collected from 1956 to 2019. The number and impact area of HABs exhibited little change from 1959 to the 1990s, sharply increased from the 1990s to 2000s, and decreased from the 2000s to 2010s. The highest number and greatest coverage of blooms occurred in the 2000s. The proportion of HABs caused by dinoflagellates increased, while the proportion caused by diatoms decreased from the 2000s to the 2010s. Toxic HAB events caused by Karenia mikimotoi increased in frequency and spatial coverage in the 2010s, especially on the central Fujian coast. Increasing concentrations of dissolved inorganic nitrogen and dissolved inorganic phosphorus have been essential for increasing HAB occurrences since the 1980s. The combined effects of eutrophication and climate change have been suggested to be important reasons for long-term changes in HABs. Knowledge of the change patterns in and the mechanisms of HABs gained in this study will extend the current understanding of HABs along the Fujian coast and support future studies on HAB monitoring, early warning, prevention, and management.
Integrating Biophysical and Economic Assessment: Review of Nature-Based Adaptation to Urban Flood Extremes
Authors: Quagliolo Carlotta , Roebeling Peter , Mendonça Rita , Pezzoli Alessandro , Comino Elena
Published: August 2022

Over the last decade, the potential of nature-based solutions (NBS) has been recognized to support climate change adaptation, by promoting sustainable urban planning. Nevertheless, a wider uptake of such solutions in urban areas faces different challenges and barriers. A comprehensive mapping of available NBS impact assessment methods could help to accelerate this process. There is, however, a lack of comprehensive systematization of economic analysis. This research aims to provide an overview of NBS impact evaluations by assessing how the scientific literature integrates such economic analysis into urban planning adaptation. A systematic review approach has been used to discuss the role of NBS in climate change adaptation. This review presents two main stages. Firstly, it identifies the biophysical–economic assessment of NBS adaptation measures to reduce urban flood extremes in coastal cities. Secondly, the NBS approaches were categorized based on the biophysical benefits (in terms of flood-risk reduction) related to each specific solution and the subsequent economic evaluation of such implementations. This research review revealed a low-level gap of integration between climate change issues and NBS analysis (i.e., it is commonly used as background condition). Most publications provide NBS biophysical impacts assessment, without combining these results with economic evaluation of the flood damages to finally achieve the avoided cost due to the implementation of such solutions. This work shows the growing interest on further research to develop spatially integrated environmental–economic assessment of NBS implementation, by highlighting the needs and opportunities of a trans-disciplinary approach to support policy-making in the framework of urban climate change adaptation.
Risk of Pulmonary Fibrosis and Persistent Symptoms Post-COVID-19 in a Cohort of Outpatient Health Workers
Authors: Fernández-Plata Rosario , Higuera-Iglesias Anjarath-Lorena , Torres-Espíndola Luz María , Aquino-Gálvez Arnoldo , Velázquez Cruz Rafael , Camarena Ángel , Chávez Alderete Jaime , Romo García Javier , Alvarado-Vásquez Noé , Martínez Briseño David , Castillejos-López Manuel , Group Research Working
Published: August 2022

Background: Infection by SARS-CoV-2 has been associated with multiple symptoms; however, still, little is known about persistent symptoms and their probable association with the risk of developing pulmonary fibrosis in patients post-COVID-19. Methods: A longitudinal prospective study on health workers infected by SARS-CoV-2 was conducted. In this work, signs and symptoms were recorded of 149 health workers with a positive PCR test for SARS-CoV-2 at the beginning of the diagnosis, during the active infection, and during post-COVID-19 follow-up. The McNemar chi-square test was used to compare the proportions and percentages of symptoms between the baseline and each follow-up period. Results: The signs and symptoms after follow-up were cardiorespiratory, neurological, and inflammatory. Gastrointestinal symptoms were unusual at the disease onset, but unexpectedly, their frequency was higher in the post-infection stage. The multivariate analysis showed that pneumonia (HR 2.4, IC95%: 1.5–3.8, p < 0.001) and positive PCR tests still after four weeks (HR 5.3, IC95%: 2.3-12.3, p < 0.001) were factors associated with the diagnosis of post-COVID-19 pulmonary fibrosis in this study group. Conclusions: Our results showed that pneumonia and virus infection persistence were risk factors for developing pulmonary fibrosis post-COVID-19, after months of initial infection.
Water Quality Prediction Using KNN Imputer and Multilayer Perceptron
Authors: Juna Afaq , Umer Muhammad , Sadiq Saima , Karamti Hanen , Eshmawi Ala’ Abdulmajid , Mohamed Abdullah , Ashraf Imran
Published: August 2022

The rapid development to accommodate population growth has a detrimental effect on water quality, which is deteriorating. Consequently, water quality prediction has emerged as a topic of great interest during the past decade. Existing water quality prediction approaches lack the desired accuracy. Moreover, the available datasets have missing values, which reduces the performance efficiency of classifiers. This study presents an automatic water quality prediction method that resolves the issue of missing values from the data and obtains a higher water quality prediction accuracy. This study proposes a nine-layer multilayer perceptron (MLP) which is used with a K-nearest neighbor (KNN) imputer to deal with the problem of missing values. Experiments are performed, and performance is compared with seven machine learning algorithms. Performance is further analyzed regarding two scenarios: deleting missing values and the use of a KNN imputer to deal with missing values. Results suggest that the proposed nine-layer MLP model can achieve an accuracy of 0.99 for water quality prediction with the KNN imputer. K-fold cross-validation further corroborates this performance.
Small-Scale Variability of Soil Quality in Permafrost Peatland of the Great Hing’an Mountains, Northeast China
Authors: Wang Xianwei , Sun Xiaoxin , Sun Li , Chen Ning , Du Yu
Published: August 2022

Permafrost peatland is a unique ecosystem that represents a huge carbon terrestrial pool. Soil quality has a relatively high level of variation at small scale in this ecosystem and is closely related to the carbon cycle. To quantify this variability, we analyzed total organic carbon, total nitrogen, total phosphorus, nutrient, and element (sodium, magnesium, potassium, and calcium), and microbial respiration activities (microbial biomass carbon, soil basal respiration, metabolic, and microbial quotients) in the humus layer to deeper soil layer of 6 plots at small scale (meters). For all samples, the coefficients of variation (CV) values of total carbon concentrations were lowest and these values of sodium, magnesium, potassium, and calcium concentrations were higher than those of total carbon, nitrogen, and phosphorus concentrations. The largest variations of total phosphorus, ash, and Na were in the 10–20 cm layer with soil depths. The litter decomposition and water table may cause this variation at small-scale. The CV values of microbial respiration activities were largest compared with soil properties. There were different correlations between basal respiration and soil properties among the plots. Our results showed that soil properties and microbial respiration activities in permafrost peatland exhibits considerable variability at small scale. This variability indicates that sampling location and number are very important in peatland studies if we want to accurately estimate the biogeochemistry in a peatland.
“Shame, Doubt and Sadness”: A Qualitative Investigation of the Experience of Self-Stigma in Adolescents with Diverse Sexual Orientations
Authors: Gilbey Dylan , Perry Yael , Lin Ashleigh , Ohan Jeneva
Published: August 2022

Many adolescents with diverse sexual orientations lead happy and fulfilled lives. However, evidence consistently suggests elevated rates of mental health difficulties in this population relative to heterosexual peers, and internalization of stigma (i.e., self-stigma) is implicated in these elevated rates. This study aimed to understand and describe the lived experience of self-stigma with respect to participants’ sexual orientations. To do this, N = 21 semi-structured interviews were conducted with adolescents aged 14–18 who are attracted to the same gender, asking about how their stigma experiences affected their views of their sexual orientation, and themselves. A community reference group of young people with diverse sexual orientations was also consulted in the development of the study, and interpretation of the themes. Through thematic analysis of the self-stigma data and the consultation process, four themes were developed: (1) stigma is a precursor to self-stigma; (2) acceptance is a precursor to self-acceptance; (3) contents of self-stigma, characterized by two subthemes: (i) self-shame (comprised of feelings of abnormality, self-disgust and/or being a ‘bad’ person) and (ii) self-invalidation; and (4) self-stigma is painful and can be damaging. There is a contrast between the way that internalized homophobia is operationalized, and the way self-stigma was characterized in this study with young people, and conceptualizing and measuring self-stigma may need to be updated. Based on the analysis, we suggest four ways to address self-stigma and its impacts: (1) individual intervention; (2) increasing acceptance in families and communities; (3) providing respectful and normalizing sexuality education and information; and (4) overcoming community stigma.
Clinical efficacy of combination therapy of arterial hypertension in patients with chronic glomerulonephritis with different blood pressure salt sensitivity
Authors:   Voronezh State Medical University named after N. N. Burdenko, Voronezh, Babkin A. P. , Malykh T. V. ,   Voronezh State Medical University named after N. N. Burdenko, Voronezh
Published: August 2022

Arterial hypertension is the main factor in the progression of CKD of any etiology; therefore, effective antihypertensive therapy is a crucial task of healthcare practice. In this work, the authors aim to study the comparative effectiveness of various types of combined antihypertensive therapy in patients with different blood pressure salt sensitivity.
Safety issues of using azole antifungals in the treatment of fungal infections in elderly patients
Authors:   FSAEI HE Peoples’ Friendship University of Russia, Moscow, Baibulatova E. A.
Published: August 2022

Fungal infections in the elderly represent an important clinical problem with significantly higher mortality compared to younger patients. The authors are studying the safety of azole antifungals in the treatment of fungal infections.
Changes in pharmacoeconomics and pharmacoepidemiology in Aktobe caused by SARS-COV-2 and bacterial pneumonia
Authors:   West Kazakhstan Medical University named after M. Ospanov, Aktobe, Republic of Kazakhstan, Balapashev A. A.
Published: August 2022

Changes in pharmacoeconomics and pharmacoepidemiology in the Aktobe region, as in the whole of Kazakhstan, is a hot topic in the light of recent world events. As domestic and foreign practice shows, many studies are devoted to analytical data in the framework of inpatient treatment. However, our interest lies in the study of how the prescription of drugs by primary care physicians in Aktobe affects the costs associated with the patient treatment. What the opportunity in choosing medicines is, taking into account patients’ financial capabilities. In addition, in this aspect, we must emphasize the significance of the protocol approved by the Ministry of Health of the Republic of Kazakhstan for the drug treatment of patients diagnosed with bacterial pneumonia. The aim of the work was to study the changes in pharmacoeconomics and pharmacoepidemiology in the city of Aktobe of the Republic of Kazakhstan, which were caused by the SARS-Cov-2 coronavirus and bacterial pneumonia.
Approaches to studying the internal picture of treatment in patients with paranoid schizophrenia
Authors:   KSMA — Branch Campus of the FSBEI FPE RMACPE of the Ministry of Health of the Russian Federation, Bashmakova O. V. , Semenikhin D. G. S ,   KSMA — Branch Campus of the FSBEI FPE RMACPE of the Ministry of Health of the Russian Federation
Published: August 2022

The concept of the internal picture of the disease is widely used in domestic medical, as well as medical and psychological practice; its practical use increases the effectiveness of therapeutic and rehabilitation processes. The development of the concept of the internal picture of the disease is the formation of ideas about the internal picture of treatment and the internal picture of pharmacotherapy. The internal picture of treatment is defined as the patient's subjective perception of the treatment process from going to the doctor to changing the lifestyle in the dynamics of the therapeutic process. In the internal picture of treatment, sensory and intellectual levels are distinguished. The study of the internal picture of the disease in schizophrenia and the dissociation of mental functions with the separation of the associative process and emotional, sensory experience, and the presence of productive symptoms contribute to the formation of an inadequate attitude towards the disease, which enhances the patient's disadaptation.
Safety control of medicines use in the Republic of Crimea and the city of Sevastopol
Authors:   Institute of Biochemical Technologies, Ecology and Pharmacy, FSAEI HE Vernadsky Crimean Federal University, Simferopol, Beitullaev A.M. , Voluiko P.A. ,   Institute of Biochemical Technologies, Ecology and Pharmacy, FSAEI HE Vernadsky Crimean Federal University, Simferopol, Matveev A.V. ,   Medical Academy named after S.I. Georgievsky, FSAEI HE Vernadsky Crimean Federal University, Simferopol, Egorova E.A. ,   Medical Academy named after S.I. Georgievsky, FSAEI HE Vernadsky Crimean Federal University, Simferopol
Published: August 2022

In economically developed countries, the frequency of registration of adverse reactions (AR) when using drugs in hospitalized patients averages 10-20% (while in developing countries this figure reaches 30-40%). About 200 thousand people die from complications caused by the use of drugs every year in the world, which determines the expediency and priority of the formation and active functioning of the pharmacovigilance system both at the level of individual pharmaceutical enterprises, medical, preventive, and pharmacy institutions, and at the level of states as a whole. The purpose of the study is to analyze the drug adverse reactions in order to assess the safety of drugs used in the Republic of Crimea and the city of Sevastopol.
Pharmacoeconomic features of increased costs of direct-acting and oral anticoagulants in a multidisciplinary hospital in 2019–2021
Authors:   SAHI Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, Kazan, Kadyseva E.R. , Kulagina L.Yu. ,   SAHI Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, Kazan
Published: August 2022

The purpose of the work is to analyze the costs of direct-acting anticoagulants and oral anticoagulants from the total cost of medicines by years in a multidisciplinary hospital, as well as to calculate the cost of a daily prophylactic dose of drugs on the example of apixaban and sodium heparin
Pharmacoeconomic features of increased costs of direct-acting and oral anticoagulants in a multidisciplinary hospital in 2019–2021
Authors:   SAHI Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, Kazan, Kadyseva E.R. , Kulagina L.Yu. ,   SAHI Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, Kazan
Published: August 2022

The purpose of the work is to analyze the costs of direct-acting anticoagulants and oral anticoagulants from the total cost of medicines by years in a multidisciplinary hospital, as well as to calculate the cost of a daily prophylactic dose of drugs on the example of apixaban and sodium heparin.
Efficacy of ceftaroline in the therapy of respiratory infections
Authors:   FSAEI HE Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow, Kamliya A. Z. , Maksimov M. L. ,   FSAEI HE Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow
Published: August 2022

The growing resistance of infectious agents to antimicrobial drugs (AMDs) is an important issue in antimicrobial therapy. The rate of emergence of new antibiotics against the background of the development and reproduction of resistant microorganisms is in stagnation. Ceftaroline, one of the AMD representatives, has valuable properties, which, among other things, distinguish it from other antibiotics. It is especially valuable for its activity against the main causative agent of the skin and soft tissue infection S. aureus (MRSA). It also exhibits activity against penicillin-, macrolide- and fluoroquinolone-resistant pneumococci, as well as Haemophilus influenzae strains that produce beta-lactamases, and provides opportunities for the treatment of respiratory infections.
Application of interactive methods in the study of antibiotic therapy in the subject of clinical pharmacology
Authors:   Tashkent Pediatric Medical Institute, Tashkent, Kasymova Sh.Sh. , Khabirova M. ,   Tashkent Pediatric Medical Institute, Tashkent
Published: August 2022

At present, almost all developed countries of the world have realized the need to reform their education systems so that students really become the central figure in the educational process, and so that the cognitive activity of the student is in the center of attention of teachers and researchers. The preparation of a highly qualified specialist who is in demand in the market and able to independently make decisions within the framework of professional competence is the main task of the teacher. Such training is impossible without the introduction of new forms and methods of teaching. The purpose and objectives of the work: to determine the effectiveness of the introduction of modern interactive teaching methods into the educational process during a practical lesson on the topic "Antibiotic Therapy" in Clinical Pharmacology.
Del laboratorio a la calle. Lecciones de la naturaleza
Authors: Echeverri López Luis Fernando
Published: August 2022

Además de que la Química de Productos Naturales es muy adecuada para hacer extensiva investigación básica, también es indudable que genera moléculas además de información estructural y biológica, para solucionar diversos problemas humanos, especialmente en el campo farmacológico, la agricultura, los cosméticos, los alimentos y otras aplicaciones industriales...
Efecto in vitro de las fracciones hexano y diclorometano del extracto etanolico de hojas frescas de Euphorbia tithymaloides L. Sobre la inhibición de las enzimas hialuronidasa, cicloxigenasa y lipoxigenasa
Authors: Castillo Contreras Osnaider J. , Alba Chávez Luz M. , Rodelo Vergara Cindy P. , Márquez Vizcano Rita L.
Published: August 2022

Euphorbia tithymaloides es una planta de interés terapéutico gracias a las propiedades curativas descritas por las comunidades que tradicionalmente le dan uso como desinflamatorio. En consecuencia, se evaluó el efecto inhibitorio in vitro de las fracciones hexano y diclorometano del extracto etanolico de hojas frescas...
Caracterización fisicoquímica de pectinas extraídas de dos especies de Opuntia
Authors: PÉREZ ZAMORA Cristina , SILVA Fernanda , MICHALUK Ariel , NUÑEZ María , GONZALEZ Ana
Published: August 2022

Las pectinas tienen un gran potencial de uso en la industria alimenticia y farmacéutica. Las principales fuentes de pectinas comerciales son las manzanas y naranjas. Pero existen otras fuentes potenciales para su extracción, como los cactus de la familia Cactaceae.
Estudio para potencializar la acción multidiana frente a lipasa pancreática y α-glucosidasa de las xantonas provenientes de Garcinia mangostana.
Authors: Cardozo M Juan C , Prieto-Rodríguez Juliet A , López-Vallejo Fabian H , Cuca-Suárez Luis E. , Patiño-Ladino Oscar J.
Published: August 2022

Las enzimas digestivas lipasa pancreática y α-glucosidasa, son importantes en el metabolismo de lípidos y carbohidratos, convirtiéndose en blancos terapéuticos atractivos para el tratamiento de la obesidad y patologías asociadas.
Aislamiento y Caracterización Química de los Glicolípidos del Alga Parda Sargassum filipendula
Authors: MUÑOZ LOSADA Kelly Johana , PUERTAS MEJIA Miguel Angel
Published: August 2022

Las algas marinas, constituyen una gran fuente de sustancias biológicamente activas, con capacidad antitumoral, antioxidante, inmunológica, hipoglucemiante, anticoagulante, antienvejecimiento, promoción del crecimiento óseo, antiviral, antibacterial, entre otros.
Murraya paniculata inhibe el crecimiento in vitro de Plasmodium falciparum en eritrocitos humanos
Authors: Vergara Saray , Arrieta Nicole , Diaz Fredyc , Moneriz Carlos
Published: August 2022

La malaria continúa siendo un problema de salud pública en muchas regiones del mundo. La situación empeora por la cada vez más difundida resistencia a los antimaláricos de primera línea, haciendo que sea necesario buscar nuevas opciones que permitan recuperar la eficacia terapéutica frente a la malaria.
Composición química y nutricional de la Uva camarona: un arándano endémico de alta montaña.
Authors: Gil Archila Elizabeth , Rojas-Bautista Felipe , Garcia Nestor , Carvajal Vasquez Jorge Andres
Published: August 2022

La familia Ericaceae es una familia representativa del Neotrópico cuyos frutos son conocidos por su alto contenido de antioxidantes. En específico el género Cavendishia, un género endémico del Neotrópico, que se encuentra distribuido en ecosistemas de alta montaña y páramos...
Antocianinas en los Té de hojas frescas de Justicia secunda Vahl Acanthaceae.
Authors: De La Rosa Márquez Isaías , Castillo Contrera Osnaider , Recuero Harol , Peñuela Josefina , Márquez Vizcaíno Rita Luz
Published: August 2022

Justicia secunda Vahl. Planta de amplio uso tradicional y medicinal por la población de la costa caribe colombiana. Los flavonoides son considera excelentes antioxidantes, reaccionan con los radicales libres para prevenir las degradaciones asociadas a su intensa actividad sobre los fosfolípidos de las membranas.
Modelo metabólico a escala genómica de células de Thevetia peruviana cultivadas en suspensión.
Authors: ORTEGA Angie , MENDOZA Dary , RIOS Rigoberto , Rios Mario
Published: August 2022

Thevetia peruviana, es una planta ornamental fuente de varios metabolitos secundarios, con aplicaciones farmacéuticas.
Evaluación de la actividad antibacteriana de 30 extractos de plantas de la Región Caribe colombiana contra Pseudomona aureginosa.
Authors: Cabrera Julián , Pájaro Yina , Fillot Margarita , García Yina , Betin Alfonso , Oliveros Andrés , Quiñones Winston , Campo Mirna , Reyes Niradiz , Diaz-Castillo Fredyc
Published: August 2022

La resistencia bacteriana, es una problemática que afecta principalmente los servicios de salud y la seguridad alimentaria.
Estandarización de un extracto metanólico de cebolla roja para la detección de proteínas fosforiladas en sds-page
Authors: Rodríguez-Cavallo Erika , Arrieta Vergel Karen , Gaviria Figueroa Isis , Marrugo-Padilla Albeiro , Méndez-Cuadro Darío
Published: August 2022

La fosforilación proteica, es una modificación postraduccional reversible, asociada a un sin número de procesos celulares vitales como la transducción de señales, diferenciación celular, desarrollo, control del ciclo celular y regulación de rutas metabólicas.
Gündelik Hayatın Kadına Dayattığı Yaşam: Bir Kadınlık Hikâyesi Olarak "Hep Yarın"
Authors: GÜLDAŞ Zühal , ARDALI BÜYÜKARMAN Didem
Published: August 2022

Bu makalede Cahit Uçuk’un Hep Yarın romanında, gündelik hayatın kadına dayattığı yaşam ve bunun bir kadınlık hikâyesi üzerinden nasıl ele alındığı sunulmuştur. Roman, Henri Lefebvre’nin gündelik hayatın sefaleti ve büyüklüğü diye nitelendirdiği gündelik hayatın iki açısı üzerinden ele alınmış olup söz konusu iki açıyı anlatırken ortaya çıkan çeşitli kimliklerin açıklanmasında Carl Gustav Jung’un arketipsel yaklaşımından yararlanılmıştır. Çalışmada söz konusu olan eserin en önemli özelliği, baş kahraman Nevbahar’ın gündelik hayatın zorunlulukları altında ezilirken kendi kadınlığından, isteklerinden vazgeçmemesi, hayatını bir kadın yazara anlatarak romanlaştırması ve böylelikle gündelik hayatın sefalet kanadından gündelik hayatın büyüklüğüne geçerek içinde bulunduğu yeknesak hayatı değiştirmesidir. Bu açıdan Nevbahar’ın kadınlık hikâyesinin anlatımında ilk olarak gündelik hayatın sefaletine yer verilmiş, karakterin taktığı sosyal maskeler iki kategoride incelenmiştir. İkinci olarak, gündelik hayatın büyüklüğü üzerinde durularak bu adlandırmaya örnek oluşturan Nevbahar’ın kadınlığının keşfi, onun hayatına girmiş olan üç erkekle ilişkisi çerçevesinde; Nevbahar’ın sanatla olan bağı ise bir sanat dalıyla uğraşması ve hayatını romanlaştırması açısından ele alınarak inceleme tamamlanmıştır.
Kazak Destanlarında Kurtarıcı Tipi
Authors: ÖZCAN GÜLER Derya , USTA Mustafa
Published: August 2022

Yaratıcı ile ilişkilendirilerek kutsallık atfedilen, olumlu tipler içinde yer alan, kahramanın ve yardımcılarının mistik koruyucusu ve destekleyicisi olan kurtarıcı tipi; savaşçı bir toplumun güçlü kalmasını sağlayan önemli destan tiplerinden biridir. Kurtarıcı tipinin Kazak destanlarında üstlenmiş olduğu işlevleri ortaya koyabilmek için makalede eylem merkezli bir çalışma yürütülerek elli dokuz destan incelenmiştir. İncelenen bu destanların on yedisinde kurtarıcı tipinin varlığı belirlenmiştir. Bu destanlarda kurtarıcı tipi darda kalanı kurtarma, yönlendirme veya görev verme, çocuksuzluk sorununa çare bulma, haber veya bilgi verme, kahramanı eğitme ve erginleme olmak üzere beş eylem sergiler. Bu eylemlerden hareketle kurtarıcı tipinin Kazak destan dünyasındaki işlevleri ortaya konmuş; Türk toplumunda kurtarıcı tipinin manevi bir güçle darda kalanı koruduğu, çeşitli sorunların çözümünde bilgeliği ile halkla yaratıcı arasında aracılık yaptığı tespit edilmiştir. Mistik bir destekçi olan kurtarıcı tipi vasıtasıyla toplum bir taraftan kahramanın kutsallığını pekiştirerek idealleştirmiş, diğer taraftan da zorda kaldığı anlarda bile kendisine yardım edecek olan bir yardımcının varlığını hissederek güçlü ve ümitli olmuştur. Bu sayede, savaşçı bir toplumun yaşanan problemler karşısında güçlü kalması sağlanmış ve kahraman nezdinde toplum da koruyucu bir çember içine alınmıştır.
Rübâb-ı Şikeste'de Sabah İzlenimleri
Authors: ERDOĞAN ÇELTİK Seher
Published: August 2022

Zaman kavramı, üzerinde en çok düşünülen ancak tam olarak bir tanımı yapılamayan, yapılan tanımların hiçbirinin genel kabul görmediği bir olgudur. Öznel, nesnel, toplumsal ve sosyolojik zaman olarak çeşitli tasniflere tâbi tutulan zamanın toplumlar için farklı zihniyetlerin tezahürü olduğu görülür. Doğu ve Batı toplumlarının zaman algılarındaki farklılık da bu bağlamda değerlendirilir. Nitekim Doğu için zaman bir döngüsellik ifade ederken Batı, zamanı çizgisel olarak algılar. Türk toplumunda zaman algısı Tanzimat'la birlikte değişmeye başlamıştır. Osmanlı toplumunun Batılılaşma arzusu zaman algısını da etkilemiştir. Döngüsel zaman anlayışı yerini yavaş yavaş süreklilik ifade eden Batı algısına bırakmıştır. Türk edebiyatında Edebiyat-ı Cedîde adıyla bir döneme damgasını vuran bir edebî anlayış içerisinde adını zikrettiğimiz Tevfik Fikret'in zaman algısının da Tanzimat'la başlayan değişimden nasiplendiğini söylemek mümkündür. Onun şiirlerinde zaman sorunsalı sıklıkla karşımıza çıkar. Tevfik Fikret'in zamanı algılayışında; sanat anlayışı, yaşadığı dönem ve yetiştiği geleneksel kültürün izlerini sürmek mümkündür.Bu çalışmada Tevfik Fikret'in Rübâb-ı Şikeste adlı kitabındaki şiirlerde geçen sabah vakti ve bu vakti ifade için kullanılan benzer kelime ve kelime gruplarından hareketle şairin zaman algısı üzerinde durulmak istenmiştir. Bu bağlamda Rübâb-ı Şikeste taranmış; fecir, sabah, subh, seher ve tulû kelimeleriyle oluşturulan tamlama ve imajlar tespit edilmiştir. Tespit edilen kullanımlardan hareketle şair için sabah vaktinin ne ifade ettiği, Tevfik Fikret'in anlam ve imaj dünyasında sabah vaktinin nasıl algılandığı ortaya çıkarılmak istenmiştir.
Física moderna no ensino médio: uma avaliação do aprendizado qualitativo assimilado pelos alunos
Authors: Coêlho Vinicius Borges , Guimaraes Ian Gil Mota , Pompermaier Márcio Augusto Campos , Souza Rafael Pissinati de , Junior Moacy José Stoffes , Stein Cléver Reis
Published: August 2022

O presente artigo teve como principal objetivo avaliar a capacidade de alunos do ensino médio em assimilar fenômenos descritos pela física moderna, à pesquisa foi realizada na Escola Estadual de Ensino Fundamental e Médio Barão do Solimões na cidade de Porto Velho – RO. Este trabalho foi conjecturado em virtude de este conteúdo não ser contemplado no currículo escolar de física para o ensino médio, isso faz com que muitos alunos concluam o ensino médio sem conhecer as contribuições da física moderna e dos pesquisadores para o surgimento de novos recursos tecnológicos. Com o intuito de avaliar a assimilação dos conceitos qualitativos de física moderna por parte dos aprendizes, realizamos uma aula experimental composta por um aparato desenvolvido com material de baixo custo e/ou reciclado, seguido da aplicação de um questionário avaliativo. Essa metodologia resultou em bons frutos, uma vez que os resultados das respostas por parte dos estudantes foram em sua maior parte assertivas. Indicando que a demonstração experimental conseguiu despertar a atenção dos educandos fazendo-os indagar sobre os fenômenos apresentado. Além de proporcionar o desafio de determinar o diâmetro de um fio de cabelo com base no calculo da difração e interferência da onda eletromagnética.
The View of Micropropulsion Technology for China’s Advanced Small Platforms in Deep Space
Authors: Wei Yanming , Yan Hao , Liu Xuhui , Yu Yang , Geng Jinyue , Chen Tao , Fu Tuoqu , Su Gaoshi , Hu Yu , Han Daoman
Published: August 2022

In this paper, micropropulsion systems are analyzed in conjunction with the various mission requirements of China’s deep space exploration. As a great challenge facing the world, deep space exploration can be enabled only in a few countries with a success rate of around 50%. With the advancement of spacecraft and scientific instruments, it is now feasible to build small and low-cost spacecraft for a variety of deep space missions. As spacecraft become smaller, there is a need for proper micropropulsion systems. Examples of propulsion system selections for deep space exploration are discussed with a focus on products developed by Beijing Institute of Control Engineering (BICE). The requirements for propulsion systems are different in lunar/interplanetary exploration and gravitational wave detection. Chemical propulsion is selected for fast orbit transfer and electric propulsion for increasing scientific payloads. Cold gas propulsion and microelectric propulsion are good choices for space-based gravitational wave detection due to the capability of variable thrust output at the micro-Newton level. The paper also introduces the sub-1-U micropropulsion modules developed by BICE with satisfactory performance in flight tests, which are promising propulsion systems for small deep space platforms. A small probe with an electric sail propulsion system has been proposed for the future solar system boundary exploration of China. The electric sail serves as not only a propellant-free thruster but also a detector probing the properties of the space medium.
Engineering Liquid-Vapor Phase Transition for Refreshable Haptic Interfaces
Authors: Wang Wei Dawid , Ding Zhengbing , Lee Yongkyu , Han Xu
Published: August 2022

Haptics as a communication medium has been increasingly emphasized across various disciplines. Recent efforts have focused on developing various haptic stimulation technologies; however, most of them suffer from critical drawbacks stemming from their bulk, complexity, large power input, or high cost. Here, we describe a strategy to design portable and affordable refreshable haptic interfaces composed of an array of individually addressable and controllable liquid pouch motor-based haptic units embedded in either rigid or flexible substrates for different application contexts. The pouch motor filled with low boiling fluid, under a controlled manner, expands or contracts by Joule heating or cooling, enabling the haptic pin in contact to be protruded or retracted. Programming the actuation sequence of an array of haptic units enables the haptic interface to apply different stimuli to the skin to convey corresponding information. We finally demonstrate the applications to portable rigid braille displays and flexible epidermal VR devices. This study opens the avenue to the design of ubiquitous refreshable haptic interfaces that is portable, affordable, scalable, and uninjurious.
Highly Sensitive Temperature Sensor Based on Coupled-Beam AlN-on-Si MEMS Resonators Operating in Out-of-Plane Flexural Vibration Modes
Authors: Tu Cheng , Yang Ming-hong , Zhang Zi-qiang , Lv Xiu-mei , Li Lei , Zhang Xiao-Sheng
Published: August 2022

This paper reports a type of highly sensitive temperature sensor utilizing AlN-on-Si resonators with coupled-beam structures of double- and triple-ended-tuning-fork (D/TETF). For both resonators, the out-of-plane flexural mode is adopted as it favors the effect of thermal mismatch between the composite layers inherent to the AlN-on-Si structure and thus helps attain a large temperature coefficient of resonant frequency (TCF). The analytical model to calculate TCF values of D/TETF AlN-on-Si resonators is provided, which agrees well with the finite-element simulation and experimental results. The resonant temperature sensor is built by closing the loop of the AlN-on-Si resonator, a transimpedance amplifier, a low-pass filter, and a phase shifter to form an oscillator, the output frequency of which shifts proportionally to the ambient temperature. The measured sensitivities of the temperature sensors using D/TETF resonators are better than -1000 ppm/°C in the temperature range of 25°C~60°C, showing great potential to fulfill the on-chip temperature compensation scheme for cofabricated sensors.
МОТИВНА СТРУКТУРА ТЕКСТУ ЯК ЛІНГВІСТИЧНА ПРОБЛЕМА
Authors: Заоборна М. С.
Published: August 2022

Осмислено феномен мотивної структури як спосіб втілення в тексті семантико-прагматичної категорії мотиву, сутність якої пов’язана з усвідомленими чи неусвідомленими внутрішніми станами, що спонукають до діяльності, забезпечуючи реалізацію в ній особистісних смислів автора (наратора) й персонажів. Схарактеризовано закономірності організації мотивної структури, що узгоджуються з динамікою модусних планів тексту в аспекті реалізації інваріантної моделі “перцептивний модус ~ емотивний модус ~ ментальний модус ~ вольовий модус”. Описано інваріантну модель мотивної структури та простежено характер її варіативності відповідно до типу письма.
Impact of the COVID-19 Pandemic on Elective and Emergency Inpatient Procedure Volumes in Switzerland – A Retrospective Study Based on Insurance Claims Data
Authors: Rachamin Yael , Meyer Matthias R. , Rosemann Thomas , Grischott Thomas
Published: August 2022

Background: The severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) pandemic forced hospitals to redistribute resources for the treatment of patients with coronavirus disease 2019 (COVID-19), yet the impact on elective and emergency inpatient procedure volumes is unclear. Methods: We analyzed anonymized data on 234 921 hospitalizations in 2017-2020 (55.9% elective) from a big Swiss health insurer. We used linear regression models to predict, based on pre-pandemic data, the expected weekly numbers of procedures in 2020 in the absence of a pandemic and compared these to the observed numbers in 2020. Compensation effects were investigated by discretely integrating the difference between the two numbers over time. Results: During the first COVID-19 wave in spring 2020, elective procedure numbers decreased by 52.9% (95% confidence interval -64.5% to -42.5%), with cardiovascular and orthopedic elective procedure numbers specifically decreasing by 45.5% and 72.4%. Elective procedure numbers normalized during summer with some compensation of postponed procedures, leaving a deficit of -9.9% (-15.8% to -4.5%) for the whole year 2020. Emergency procedure numbers also decreased by 17.1% (-23.7% to -9.8%) during the first wave, but over the whole year 2020, net emergency procedure volumes were similar to control years. Conclusion: Inpatient procedure volumes in Switzerland decreased considerably in the beginning of the pandemic but recovered quickly after the first wave. Still, there was a net deficit in procedures at the end of the year. Health system leaders must work to ensure that adequate access to non-COVID-19 related care is maintained during future pandemic phases in order to prevent negative health consequences.
COVID-19 Aftermath: Direction Towards Universal Health Coverage in Low-Income Countries Comment on "Health Coverage and Financial Protection in Uganda: A Political Economy Perspective"
Authors: Tangcharoensathien Viroj , Panichkriangkrai Warisa , Witthyapipopsakul Woranan , Patcharanarumol Walaiporn
Published: August 2022

Progressive realization of universal health coverage (UHC) requires health systems capacity to provide quality service and financial risk protection which supports access to services without financial hardship. Government health spending in low-income countries (LICs) has been low and heavily relied on external donor resources and out-of-pocket payment. This has resulted in high prevalence of catastrophic health spending or foregone care by those who cannot afford. Under fiscal constraints posed by pandemic, reforms in LICs should focus on efficiency through health resource waste reduction. Targeting the poor even with low level of health spending can make a significant health gain. Investment in primary healthcare and health workforce is the foundation for realizing UHC which cannot be postponed. Innovative tax on health hazardous products, conditional debt relief can increase fiscal space for health; while international collaboration to accelerate coronavirus disease 2019 (COVID-19) vaccine coverage can bring LICs out of acute phase of pandemic.
الضبط الإداري لأعمال الحماية الإدارية في العراق
Authors: عزيز زينب , مرزة وليد
Published: August 2022

يتطرق هذا البحث إلى أعمال الحماية الإدارية وهي منوطا بسلطة الضبط الإداري, والأخير له علاقة مباشرة بالحريات العامة, إذ أن صيانة النظام العام من مختلف الكوارث والأضرار تقتضي في العادة فرض قيود عليها

وفي مجال حماية السكان والممتلكات تضطر الإدارة إلى وضع قيود على بعض  الحريات العامة على وجه الخصوص, وذلك إن الحماية الإدارية تهدف إلى حماية آمن المواطنين من المخاطر وسلامة ممتلكاتهم, والوقاية من المخلفات الضارة التي يمكن أن تنشا عن ممارستها, وقد تبين لنا أن إدارة الحماية الإدارية تتخذ مجموعة من التدابير للحد من الكوارث والأضرار, فتعمل على تنظيم العمل ووضع الضوابط يكون الهدف منها حماية السكان والممتلكات.

وتناولنا موضع الضبط الإداري لأعمال الحماية الإدارية في العراق في مبحثين, فأفردنا المبحث الأول لتعريف الحماية الإدارية وموضوعه, أما المبحث الثاني فدرسنا فيه تعريف الضبط الإداري وأغراضه ووسائل الحماية الإدارية .

 وقد توصلنا إلى جملة من النتائج والتوصيات التي نأمل أن يتم الأخذ بها عند ممارسة الإدارة لسلطات الضبط الإداري لحماية السكان وممتلكاتهم في العراق.
PEMBUATAN APLIKASI PEMBELAJARAN RUKUN ISLAM DAN KUMPULAN DO’A BERBASIS ANDROID
Authors: Rahman Miftahur , Dasuki Moh.
Published: August 2022

Pesatnya ilmu pengetahuan teknologi modern, seperti halnya smartphone pada era saat ini, tentunya ada dampak positif dan juga ada dampak negatifnya. Dampak positifnya, antara lain adalah kemudahan orang dalam memperoleh informasi, pengetahuan secara praktis dan dinamis. Sedangkan dampak negatifnya adalah dalam menggunakan smartphone itu sendiri, seperti membuka situs-situs yang tidak pantas dilihat oleh pengguna, kecanduan game online, sehingga terjadi malas belajar, menghambat dalam beraktifitas, dan lain sebagainya. Selain itu juga terdapat masalah yang signifikan yaitu banyak orang yang sudah melupakan rukun islam, banyak dari kalangan anak-anak hingga orang dewasa belum mengetahui tentang rukun islam. Untuk menanggulangi masalah tersebut diusulkan solusi pembuatan aplikasi yang berisi informasi pengetahuan Rukun Islam yang ditambah fitur kumpulan do'a yang mana dengan dibuatkannya aplikasi rukun islam berbasis android ini diharapkan bermanfaat bagi masyarakat dalam mempelajari materi didalamnya. Penelitian ini menggunakan metode pengembangan rekayasa perangkat lunak waterfall dan untuk pembuatan aplikasi ini menggunakan perangkat lunak yang open sourceyaitu bahasa pemrograman java dengan IDE Eclipse indigo . Sehingga dihasilkan program aplikasi media pembelajaran Rukun Islam dan Kumpulan Do'a berbasis android yang memudahkan masyarakat pada umumnya dalam mempelajari informasi pengetahuan Rukun Islam dan Kumpulan Do'a harian yang lebih bermanfaat.
Pembuatan Pola Tulisan Tangan Melalui Webcam Dengan Metode L*a*b* Color Space
Authors: Sahwari Sahwari , Jasuli Untung
Published: August 2022

Kemajuan teknologi membuat sebuah perangkat komputer memiliki kemampuan yang tinggi untuk meningkatkan kinerja dalam pengolahan data menjadi informasi. Salah satu hal yang dapat dilakukan adalah memanfaatkan teknologi tersebut untuk memasukkan data kedalam komputer. Banyak sekali teknik yang dapat memudahkan pengguna untuk memasukkan data ke dalam komputer salah satunya adalah menggunakan webcam untuk pengambilan gambar yang selanjutnya bisa diproses atau disimpan dalam komputer. Tidak menutup kemungkinan bagi seorang pengguna yang awalnya melakukan pembuatan pola tulisan tangan menggunakan touch screen atau menggunakan mouse, sekarang menggunakan webcam sebagai alat input pembuatan pola tulisan tangan tersebut.

Untuk itulah perlu diadakan penelitian untuk membuktikan kemungkinan tersebut yaitu pengenalan pola dari isyarat yang diberikan pengguna melalui webcam dengan warna sebagai acuan untuk penulisan pola. Pola tersebut ditulis melalui webcam menggunakan acuan warna yang diklasifikasikan dengan metode L*a*b* color space berdasarkan karakteristik warna yang telah dipilih.

Dalam penelitian ini telah dihasilkan aplikasi yang mampu melakukan pembuatan pola tulisan tangan yang diisyaratkan melalui webcam berdasarkan warna sebagai acuan untuk melakukan pembuatan pola tulisan tangan.