bluuebunny/crossref_metadata_2025 huggingface dataset:
História da África, Diáspora e perspectivas emancipatórias
Authors: Jesus Leandro , Oliveira de Santana Elisângela
Published: August 2023

No continente africano e na diásporanegra, têm acontecido movimentos peladescolonização do saber, a despeito de séculos de reiterações de discursos pseudocientíficos que celebraram supremacias brancas europeias nos espaços de produção e circulação de conhecimentos. Ao longo do século XX, diferentes gerações de pesquisadoras/es, estudantes e ativistas mobilizaram empreendimentos intelectuais de profundos impactos políticos dentro e fora das universidades, trazendo à tona a problemática da (re)escrita da História no enfrentamento ao racismo e ao eurocentrismo. Neste artigo, discutimos as formas pelas quais a pesquisa e o ensino de História da África têm se relacionado com práticas de autoemancipação, autogestão e autorrepresentação por meio de experiências no Brasil e na África do Sul.
An Assessment on the Necessity of Continuous Innovation Ecosystems Via Multidisciplinary Smart Specialties Approach
Authors: EFE Ahmet
Published: August 2023

Smart specialization, one of the newest paradigms, provides new insights and priorities to entrepreneurs and companies by supporting economic and technological activities and strengthening existing scientific and industrial specialization models. This study argues that a multidisciplinary approach to innovation and smart specialties from economics, religion, and business domains should be applied to evaluate the smart specialization strategy and development process, a new system within regional innovation, and sustainable development approaches. Therefore, in this article, holistic innovation modeling is carried out by focusing on the definitions of innovative regional development strategies and necessary policies, and by considering the basic elements of the smart specialization strategy related to innovation and sustainable development.
Elektronik Ağızdan Ağıza İletişim (E-wom) Katılımının Satın Alma Niyeti Üzerine Etkisi: Sosyal Ticaret Örneği
Authors: AKIN Mustafa Said , ÖZTÜRK Abdülkadir
Published: August 2023

Sosyal ticaret, elektronik ortamlar ve sosyal medyanın da gelişmesiyle birlikte, geleneksel ticaret faaliyetlerinin, elektronik ortamlarda var olma çabası neticesinde gün geçtikçe önem kazanmaya devam etmektedir. Özellikle işletmeler ve pazarlama karar vericileri açısından sosyal ticaretin araştırılması, tüketicileri daha iyi anlamak için fırsatlar sunarken, daha doğru politikaların benimsenmesine de yardımcı olmaktadır. Bu çalışmanın amacı, sosyal ticaret kapsamında, elektronik ağızdan ağıza iletişime karşı tutumun ve elektronik ağızdan ağıza iletişim katılımının, tüketicilerin satın alma niyetlerindeki etkileri ortaya çıkarmaktır. Elde edilen bulgulara göre, anket katılımcısı tüketicilerin, elektronik ağızdan ağıza iletişim karşı tutumlarının elektronik ağızdan ağıza iletişim katılımı üzerinde, elektronik ağızdan ağıza iletişim katılımının ise satın alma niyeti üzerinde etkisi olduğu anlaşılmıştır. Elektronik ağızdan ağıza iletişime karşı tutumun ise satın alma niyeti üzerinde herhangi bir etkisi bulunamamıştır.
The effect of mnemonics method on students’ retention and learning outcomes in the learning of biology
Authors: Atimi Nisa Dhania , Afandi Afandi , Tenriawaru Andi Besse
Published: August 2023

The mnemonic method is one of the procedures that is considered effective for improving students’ learning outcomes and memory. This study aims to examine the effectiveness of the mnemonics methods in improving students' retention and learning outcomes in Biology class on the System of Biological Classifications. The pre-experimental method with one group of pre-test and post-test design was applied in this study. Thirty students of a secondary school in Pontianak were used as research samples taken by using intact group random sampling. The learning outcomes test used was 20 multiple-choice questions with four options having a validity level of 0.86 and a reliability of 0.87. Based on the data analysis, it was concluded: (1) the average learning outcomes before treatment was 48.50 and after treatment was 72.50; (2) the differences in the average student learning outcomes before treatment was = 48.50 and after treatment was = 72.50 (t = 5.517, p <0.05); (3) the level of increase in retention power after treatment of R = 0.85.06% is high. It is recommended that Science-Biology teachers apply mnemonics in a varied and sustainable manner to make it more useful and according to the content of the teaching material to be taught.
Ethnobotany of robusta coffee (coffea canephora pierre ex a. froehner) as a spiced coffee drink of the indigenous people of bale village on halmahera island
Authors: Tamalene M. Nasir Tamalene , Bahtiar Bahtiar , Suparman Suparman , Slamet Hariyadi
Published: August 2023

A study on inherited local knowledge of spiced coffee ethnobotany in processing coffee by the people of Bale Village is necessary to depict the sub-system coffee processing. Bale Village is situated on Halmahera Island. It is one of the villages in the Oba Sub-district, Tidore Kepulauan Regency. The village is known as a producer of coffee bean and coffee powder. This study on local knowledge is an initiative to acquire information on spiced coffee. The research design is a survey design to investigate and document the knowledge of the utilization of spice plants in coffee drinks as a traditional beverage of people in Bale Village. Data are analyzed in a qualitative-thematic manner to describe respondents’ ethnobotanical knowledge and are independent of the researcher’s assessment. The research results indicate that spiced coffee made by the villagers uses six spice plants, namely clove (Syzygium aromaticum (L.), red ginger (Zingiber officinale Roscoe.), cinnamon (Cinnamomum verum J. Presl.), kara benguk (Mucuna pruriens (L.) DC.), nutmeg (Myristica fragrans Houtt.), and pandan (Pandanus amaryllifoliusRoxb.). Stages in the making of spiced coffee with the 5M method include: 1) determine the composition of spiced coffee, 2) grind spiced coffee beans into powder, 3) prepare water, 4) stir the spiced coffee and 5) enjoy the spiced coffee
The influence of knowledge about environmental change, information reception, and naturalistic intelligence on environmental care
Authors: Abdullah Nurfiana , Daud Firdaus , Darwis Muhammad , Muhiddin Muhiddin , Arifin Arifah Novia
Published: August 2023

This study is an ex post facto research that aims to discover the influence of knowledge on environmental changes, receiving information, on environmental awareness and the influence of environmental changes, receiving information on environmental awareness by involving naturalistic intelligence. The study population was all students of grade XI at SMAN in East Banggae subdistrict in Majene district, namely SMAN 1 Majene, SMAN 2 Majene, and SMAN 3 Majene. The research instrument employed a test of environmental change knowledge, a questionnaire for information reception, naturalistic intelligence and environmental awareness. The results showed that, 1) environmental changes are in the very low category, information reception is in the medium category, naturalistic intelligence is in the high category.
Analysis science process skills of grade viii students on digestive system material
Authors: Lestari Tuti , Oktaviani Velia
Published: August 2023

Science process skills are the ability to solve problems through scientific research. Science process skills serve as a foundation for other cognitive skills such as logical thinking skills, reasoning and problem solving, making students grow into individuals who are able to access information and understand information, so that students are able to apply the knowledge they acquire in real terms. -world context. For this reason, science process skills are important to be trained in the learning process. The purpose of this study was to analyze the mastery of science process skills for Grade VIII students of SMP Negeri 15 Padang on the digestive system material. This research is a descriptive research with a quantitative approach. The population of this study were all students of class VIII, the sampling technique was carried out by random sampling technique, the number of students who were sampled was 60 students. Data collection techniques were carried out by observation, documentation and written tests. The results showed that the average value of each indicator was divided into three categories, namely high, medium and low. From the results of the study it can be seen that: (1) students get the low category on the indicators of asking questions and formulating hypotheses with a value of 40 and 38.5, (2) students get the medium category on the indicators of investigative skills, classification, interpretation, communication, application. concept, conclude, and predict with a value of 61.2; 69; 52; 52; 60.7; 58.5; and 61.9, (3) students are classified as high on the observation skills indicator with a value of 90 and the average value of  mastery of science process skills by students based on the ten indicators used is 58.38, so it can be concluded that mastery of students' science process skills is in medium category.
The correlation between digital competence and steam readiness of biology pre-service teacher
Authors: Adhani Aidil
Published: August 2023

Digital competence is one of the things that pre-service teachers need to have in order to survive in global competition. The goal of this reasearch is to know the correlation between digital competence of biology pre-service teachers and their readiness to apply STEAM-oriented learning. This research is a bivariate correlational quantitative research. The sampling technique used in this study is the quota sampling technique with number of sample are 90 students. The instrument used in this study was a questionnaire to measure students' digital competency skills and their readiness for STEAM. The data analysis technique in this study is inferential statistical analysis in the form of a bivariate correlation test (Spearman Rank correlation). The Correlation Coefficient value shows a coefficient of 0.622, meaning there is a strong relationship between digital competence and readiness for STEAM. The digital competence of pre-service teachers is considered necessary in STEAM-oriented learning because technology and digital tools play an essential role in improving the quality of learning and enabling more interactive, innovative, and fun learning experiences.
The contribution of cognitive ability and critical thinking skills on the problem solving skills of biology education profession students using case method learning
Authors: Siswati Bea Hana , Suratno Suratno
Published: August 2023

Problem-solving skills have many benefits, especially for lifelong learning. Learners are equipped with these abilities to be able to survive in life and in their profession. Problem-solving skill is closely related to cognitive ability and critical thinking skill. This research aims at determining the contribution of students’ cognitive ability and critical thinking skill on their problem-solving skill. This correlational research included 127 students taking education profession courses. The collected data were analyzed using correlation regression SPSS Version 23 software. The results of the data analysis showed that students’ cognitive abilitys and critical thinking skills had a significant correlation with their problem-solving skills. The relative contribution of the cognitive ability and the critical thinking skill was 94.8%. While the effective contribution of cognitive ability and critical thinking skills toward the students’ problem-solving skills was 68.4% and 26.4% respectively. The positive correlation among these variables can be used as a basis for implementing the case method in classroom learning activities in that the implementation of the case method has positive effects on the student’s cognitive abilitys, critical thinking skills, and problem-solving skills in Biology Education students.
Improving spatial and temporal monitoring of dredging operations incorporating unmanned technologies
Authors: Wilkins Justin , McQueen Andrew , Suedel Burton
Published: August 2023

The US Army Corps of Engineers (USACE) is responsible for maintaining safe and navigable waterways through the periodic dredging of shoaled sediment from federal navigation channels. While dredging, a portion of the bottom sediments become resuspended creating a sediment plume near the dredging operation. Suspension of sediments during dredging and dredged sediment disposal operations continues to be a primary concern of regulatory agencies charged with the protection of environmental resources. Consequently, almost all dredging projects incorporate some level of regulatory compliance monitoring dedicated to measuring sediment resuspension. For numerous reasons the conventional approach using manned surface vessels to perform compliance monitoring is frequently ineffective in both adaptively managing dredging projects and ensuring true environmental protection. Advancements in unmanned platforms and payload technologies offer new and potentially more robust alternatives to conventional platforms. In this study, the use of unmanned aerial system (UAS) and weather balloon mounted camera imagery was demonstrated, and the use of an unmanned surface vessel (USV) to monitor turbidity in navigation channels and near a dredging operation. The imagery from the UAS and weather balloon were compared to in-situ turbidity measurements in a turbid distributary channel and near a dredging operation, while the USV was used to learn more about in-situ turbidity associated with passing vessels in a navigation channel. The results of the demonstrations show the unmanned technology bundled with off-the-shelf payloads can help to produce evidence-based information through easily interpreted aerial imagery and in situ measurements which can help to inform and manage water quality in areas where sediment plumes are an environmental concern.
Scaling and sensitivity analysis of machine learning regression on periodic functions
Authors: Trahan Corey , Rivera Peter
Published: August 2023

In this report we document the scalability and sensitivity of machine learning (ML) regression on a periodic, highly oscillating, and 𝐶∞ function. This work is motivated by the need to use ML regression on periodic problems such as tidal propagation. In this work, TensorFlow is used to investigate the machine scalability of a periodic function from one to three dimensions. Wall clock times for each dimension were calculated for a range of layers, neurons, and learning rates to further investigate the sensitivity of the ML regression to these parameters. Lastly, the stochastic gradient descent and Adam optimizers wall clock timings and sensitivities were compared.
Comparative Analysis of Collection and Distribution of Zakat Institution Funds in Indonesia
Authors: Fatha Ainul , Pahlevi Mohamad Syahreza
Published: August 2023

Zakat is an important instrument in Islamic philanthropy that can be beneficial in socio-economic terms. The purpose of this study is to analyze the development of the collection and distribution of zakat funds at zakat institutions in Indonesia. This research uses a quantitative method using horizontal analysis. The results of the study show that the collection and distribution of zakat funds for each zakat institution have different graphs are increasing, decreasing, and fluctuating. The collection of zakat funds in the 2016-2019 period shows that the largest collection of funds is LAZ Dompet Dhuafa, the proportion of which reaches 30% of the total funds. Meanwhile, LAZ Mizan Amanah is a zakat institution with the lowest proportion of fundraising, namely 1% of the total funds. The distribution of zakat funds in the period 2016-2019 shows that LAZ Rumah Zakat has the largest distribution of funds and LAZ Mizan Amanah is a zakat institution with the lowest proportion of channeling funds is only 1% of total funds. The implication of this research is for zakat institutions to optimize the collection of zakat funds innovatively so that they can channel more funds to the community.
Lithology, Geochemistry of the Middle Devonian Sediments and the Influence of Volcanism on Sedimentation in the Southeast of West Siberia
Authors: Saraev S.V. , Ganashilin A.S. , Izokh N.G. , Popov B.M.
Published: August 2023

—Dataset on the Middle Devonian volcanic-carbonate–terrigenous sediments of Salair and the Kuznetsk trough, submerged northward under the Mesozoic–Cenozoic West Siberian geosyneclise (WSG) cover, have been presented. Mainly deep water sediments composed of thin- and fine-grained clastic material (with predominance of tephroids) and thin-, fine-clastic biodetrital limestones with slope slide breccia, as well as turbidites and peculiar “conglomerate-like” limestones (paleoseismites) were found. Sedimentary and geodynamic environments have been reconstructed for the Middle Devonian strata. Predominantly andesitic composition of pyroclastic ashes with fewer values of felsic and basic volcanic components have been determined. The structures related to the continental margin environments of the Siberian continent, the continental slope and its basement have been found. According to sedimentary and geochemical data, the paleogeodynamic environment within the studied region was relatively stable and generally corresponded to the island arc conditions. The paleoclimate of the source area changed from semi-humid in the late Emsian–early Eifelian (Malaya Salairka age) to aridic in the middle Givetian (Kerlegesh age). Basin sediments formed in the deep water oxic environments with good water aeration, excepting euxinic environments found in the lowermost part of studied succession.
Efektivitas Penggunaan Quick Response Code Indonesian Standard (QRIS) pada UMKM (Food and Beverage) di Kabupaten Ponorogo
Authors: Septiana Alisa Salsabila  , Aji Damanuri
Published: August 2023

Advances in technology and digitization have resulted in very rapid developments in community activities such as the payment system. This research is a field research (field research) with a qualitative approach to the type of descriptive research. Where data collection uses interview techniques, observation, and documentation. Data analysis techniques include data reduction, data presentation, and conclusion. The authors use the triangulation technique to check the data's validity. This study concludes that the indicators for achieving goals are said to be effective but not optimal because MSME actors feel the ease of using QRIS, but the main goal is to follow trends; the integration indicators are said to be effective but not optimal because there are still few people who pay using QRIS even though they have received socialization and adaptation indicators are said to be ineffective. After all, the organizers have yet to conduct a follow-up survey on MSME (Food and Beverage) actors who use QRIS.
Efektivitas Program Bantuan Pangan Non Tunai Dalam Pengentasan Kemiskinan Di Kabupaten Ponorogo
Authors: Rahayu Putri , Hanik Fitriani
Published: August 2023

Poverty is the inability of individuals to meet their needs economically. One of the programs for poverty alleviation is Non-Cash Food Assistance (BPNT). The problems in the field are still many recipients of Non-Cash Food Assistance that need to be corrected. The primary purpose of this study is to analyze the realization of the BNPT program in poverty alleviation in Ponorogo district, to analyze the obstacles encountered by the BPNT program in the Ponorogo Regency area in poverty alleviation, and to analyze the effectiveness of the BPNT program in poverty alleviation in Ponorogo district. This research uses qualitative methods. The findings of this study are 1) Realization of the Non-Cash Food Assistance Program (BPNT) in Ponorogo district, namely to reduce the expenditure burden through meeting food needs. BPNT distribution involves Warung Agents taking food ingredients such as vegetables, eggs, etc. 2) Constraints of the BPNT program in poverty alleviation in Ponorogo district: inappropriate personal data resulted in the Prosperous Family Card not being issued. 3) The effectiveness of the BPNT program in poverty alleviation in Ponorogo district includes: Target accuracy needs to be more effective, Program socialization has not been effective, Program objectives have been effective, Program monitoring has not been effective because monitoring from the assistance is still ineffective.
Analisis Pengaruh Rata-Rata Lama Sekolah, Pengeluaran Per Kapita, dan Pengangguran terhadap Indeks Pembangunan Manusia
Authors: Arin Ramadhiani Soleha  , Moh. Faizin
Published: August 2023

This study aims to determine the effect of mean years of schooling, per capita expenditure, and unemployment on the human development index in districts/cities of East Java province in 2017-2021. The research method used is a quantitative method with a descriptive approach. Amount observations in this study is as many as 190 consisting of 38 districts/cities. The method of analysis of this study uses panel data regression analysis and significance test with the help of E-views 12. The results of this study explain that (1) Variable Mean Years of Schooling has a negative and significant effect on HDI. (2) The Per Capita Expenditure Variable has a negative and significant effect on HDI. (3) Unemployment variable has a negative and significant effect on HDI. (4) Variables Mean Years of Schooling, Expenditure Per Capita, and Unemployment simultaneously have a significant effect on HDI
Pengaruh DAR, CR, dan NPM Terhadap Harga Saham Perusahaan Telekomunikasi yang Terdaftar di BEI
Authors: Arum Dektaria  , Ratna Yunita
Published: August 2023

Introduction: The information obtained through the study of financial statements can be used to describe a company's performance. Investors need the results of financial statement analysis as a basis for making investment decisions because stock price movements can be seen by observing them. The share price, according to theory, will fall as the value of DAR increases. Meanwhile, if the CR and NPM values increase, the stock price will increase. However, after collecting research data, it was found that there was a discrepancy in data facts according to theory. Research Methods: This study adopts a quantitative associative research methodology. In the sampling technique, a purposive sampling technique was used, and four telecommunications businesses were taken as samples. By using MS Excel 2010 and Eviews 9 software, the research approach uses panel data analysis, starting with evaluating panel data estimation methods and continuing with selecting panel data regression models, testing classical assumptions, and testing hypotheses. Results: Based on the research above, it was found that the best estimation model chosen was the Fixed Effect Model (FEM). Furthermore, using the best choice model, classical assumption testing is carried out and the result is that the classical assumption obligation has been fulfilled. Conclusion: The results of this study, partially DAR has no significant effect on stock prices, CR has a significant effect on stock prices, and NPM has a significant effect on stock prices. Meanwhile, DAR, CR and NPM simultaneously have a significant influence on the stock prices of Indonesian telecommunications companies listed on the Indonesia Stock Exchange from 2017 to 2021.
Dampak Pembangunan Keberadaan Kampus II IAIN Ponorogo Dan Dampaknya Terhadap Perekonomian Masyarakat Di Kabupaten Ponorogo
Authors: Wida Andina  , Kenlies Era Rosalina Marsudi
Published: August 2023

Development is a continuous improvement process in society and its social system towards a better standard of living. Development is a change in the level of welfare that is measurable and occurs naturally. The changes affect not only one aspect of life but also fundamental aspects. Changes can be seen in the economic status of the people in the area, like the construction of a higher education institution in a place that will impact changes in its surroundings. The changes that occur are not only the hustle and bustle of activities but also changes in the economic field of the surrounding community because other developments around it will also follow the construction of a higher education institution. So that The main objective of this research is to find out how the influence of the development of higher education institutions has on the economy of the surrounding community. The changes brought about by the establishment of a tertiary institution certainly have an impact on the lives of the surrounding community. The impact in question is an impact that can improve the lives of the surrounding community, especially in the economic sector. The most obvious change is that in the area around the campus, many business establishments have been established, such as boarding houses, restaurants, shops, workshops, laundries, photocopiers, and so on. Establishing these businesses will open up many job opportunities for the community so that the community's economy will also improve. This research is expected to contribute to the development of economic development theory and can be helpful suggestions and references for future research.
Effect of dexmedetomidine on Sensory Evoked Potential monitoring during cervical spine surgery with total intravenous anesthesia : a randomized controlled trial
Authors: Gu Yinghua , Ye Qingshan , Min Hongxing , Liu Wenxun , Chen Jiaxin , Li Yan , Liu Xin , Wang Fa , Tian Biyun
Published: August 2023

Background :The effect of α2 adrenergic receptor agonist-dexmedetomidine on evoked potentials in cervical spinal cord remains unclear at the current stage. Therefore,this research investigates the effect of dexmedetomidine on sensory evoked potential during cervical spine surgery under total intravenous anesthesia, so as to provide reference for clinical practice.
Methods:A total of 45 patients undergoing cervical spine surgery at the teaching hospital were randomly divided into group D (Dexmedetomidine group,n=23) and group C (Control group,n=22). Both groups were anesthetized with propofol and remifentanil. Group D was infused with dexmedetomidine starting at 1ug/kg for 10 minutes before induction, and then maintained at 0.4ug/kg/h during the operation. Group C was injected with the same dose of saline. Evoked responses were evaluated under seven conditions: awaking (T0), at the end of the loading dose infusion(T1), after induction of anesthesia (T2), after intubation (T3), positioning (T4), spinal canal decompression (T5), and interbody fusion cage insertion (T6).The amplitude (N13-P15, N45-P37) and latency (N13, P15, N45, P37) of SEP, heart rate (HR), mean arterial pressure (MAP), body temperature (T), and bispectral index (BIS) were recorded at these seven time points. The pre-and post-operative red blood cell specific volume (HCT) counts, as well as the intraoperative dosage of propofol and remifentanil were recorded in both groups.
Results:A total of 40 patients completed the study. 1. Compared with T0, the N13-P15 amplitude decreased at T1 and T6 in group D （P＜0.05）, and significantly decreased at T6 in group C（P＜0.01）; The amplitude of N45-P37 decreased at T1, T5, and T6 in group D(P＜0.05) , and significantly decreased at T5 and T6 in group C（P＜0.01）.Compared with group D, the N45-P37 amplitude significantly decreased at T4 in group C （P＜0.05）.2. Compared with T0, the N13, P15, N45, and P37 latency were not statistically significant in both groups (P>0.05). 3. There was no statistical difference in MAP, HR, T, and BIS between the two groups (P>0.05) .
Conclusion:Dexmedetomidine has no effect on the amplitude and latency of SEP in patients undergoing cervical spine surgery. More importantly, dexmedetomidine may have a protective effect on nerves during the positioning process.
Trial registration:The study registered on the Chinese Clinical Trial Registry (www.chictr.org.cn), Clinical Trials identifier ChiCTR2300072621(19/06/2023).
Outcomes of Non-Vitamin K Oral Anticoagulants for Secondary Prevention in Ischemic Stroke with Atrial Fibrillation
Authors: Nam Ki-Woong , Kwon Hyung-Min , Lee Yong-Seok , Won Sung-Ho , Moon Hye-Sung
Published: August 2023

Previous studies have rarely investigated the role of non-vitamin K oral anticoagulants (NOAC) and warfarin in the secondary prevention of ischemic stroke patients with nonvalvular atrial fibrillation (NVAF). In this study, we compared the effectiveness and safety of NOAC and warfarin for secondary prevention in Korean ischemic stroke patients with NVAF. Based on the Korean National Health Insurance Service Database, this study included 21,064 oral anticoagulants-naïve acute ischemic stroke patients with NVAF between July 2015 and June 2019. The main study outcomes included ischemic stroke, systemic embolism, major bleeding, and death. During the observational periods, NOAC users had a significantly decreased risk of ischemic stroke + systemic embolism (adjusted hazard ratio [aHR], 0.86; 95% confidence interval [CI], 0.78–0.95), ischemic stroke (aHR, 0.89; 95% CI, 0.81–0.99), major bleeding (aHR, 0.78; 95% CI, 0.68–0.89), and all-cause death (aHR, 0.87; 95% CI, 0.81–0.93). Standard-dose NOAC users had a lower risk of ischemic stroke, systemic embolism, and major bleeding events than warfarin users. In contrast, low-dose NOAC users did not differ in risk from warfarin users for all outcomes. In conclusion, NOACs were associated with a lower risk of secondary thromboembolic events and bleeding complications in Korean ischemic stroke patients with NVAF than warfarin.
Associations Between Nature Exposure, Screen Use, and Parent-Child Relations: A Scoping Review
Authors: Torjinski Marina , Cliff Dylan , Horwood Sharon
Published: August 2023

Background Recent research suggests that children spend increasing amounts of time engaging in screen-based activities and less time outdoors in natural environments. There is a growing body of theory-driven literature evidencing that child screen use and exposure to nature are associated with wellbeing outcomes in contrasting ways. However, few studies have explored their combinative effects and the relational family context has been largely overlooked.
Objective This scoping review explored associations between early-late childhood nature exposure, screen use, and parent-child relations in order to identify research gaps and inform future research direction.
Methods This review was guided by Arksey and O’Malley’s five-stage methodological framework and other relevant guidelines for scoping reviews. A search of five electronic databases (PsycINFO, MEDLINE complete, ERIC, EMBASE and Cochrane library) was conducted along with additional hand-searches from inception to 9/06/2023. Peer-reviewed articles published in English between 2012-2023 were included.
Results A total of 284 articles were screened by title and abstract and full text review of 79 articles was conducted. Following additional searches (hand-search and reference lists), a total of 16 eligible articles were identified. The synthesis revealed that the relevant body of research is novel, heterogenous, and fragmented. There are various pathways through which children’s screen use and engagement with nature interact within the family context, however research exploring their synchronous and bidirectional effects on relational family processes is limited.
Conclusion Findings emphasize the importance of investigating children’s screen use and engagement with nature from a relational paradigm. Future studies should explore the mechanisms underpinning the reciprocal influences of nature and screen use on dyadic family processes and relational outcomes across early-late childhood.
OSF Registration DOI 10.17605/OSF.IO/TFZDV
Direct correlation between surface integrity and fatigue limit of surface cold worked chromium-nickel austenitic stainless steels
Authors: Maximov Jordan , Duncheva Galya , Anchev Angel , Dunchev Vladimir
Published: August 2023

Direct correlations were established between basic surface integrity (SI) characteristics (roughness, microhardness, residual stresses) obtained as a result of surface cold working (SCW) and bending fatigue limit of chromium-nickel austenitic stainless steels (CNASS). The results of experimental tests and optimization of the SCW process, implemented via hardening diamond burnishing (DB), are presented. When the requirement for the corresponding component is a high fatigue limit, the information obtained will help the researcher to find the inverse correlation between SI and finishing so that when the SCW process is implementing by another method, the same high fatigue limit can be achieved. Five roughness parameters that are functionally significant indicators of fatigue behavior, microhardness, and surface residual axial and hoop stresses form the vector of objective functions. The governing factors are the burnishing force and the number of passes. The fatigue limit was obtained by the accelerated Locati’s method. The models of the corresponding SI characteristics and the fatigue limit were obtained by a planned experiment and regression analyses. Direct correlations between SI characteristics and the fatigue limit were obtained by eliminating the variables in the corresponding pairs of models. The change trends of the microhardness and fatigue limit were found to be identical, i.e., the fatigue limit of CNASS can be controlled via inexpensively measured SI characteristics such as roughness parameters and surface microhardness. In other words, any static coldworking process can be optimized without carrying out fatigue tests by choosing these SI characteristics as objective functions and seeking a compromise optimal solution that simultaneously achieves high values of the microhardness and skewness and a low value of the roughness parameter Ra. Given the direct correlation between the microhardness and the fatigue limit, the compromise optimal solution maximizes the fatigue limit while satisfying the particular roughness requirements. The multi-objective optimization performed and comparisons made prove the effectiveness of the proposed approach.
The sFlt-1/PlGF ratio as predictor of Maternal adverse outcome in patients with suspected or placental insufficiency
Authors: Perales-Marín Alfredo , Fernández-de-la-Cruz Francis , Martínez-Triguero Marisa , Alba-Redondo Amparo , Monfort-Ortiz Rogelio , Novillo-del-Álamo Blanca , Marcos-Puig Beatriz , Morales-Roselló José
Published: August 2023

Background
sFlt-1/PlGF ratio has been proposed to herald adverse Pregnancy outcome (APO). Several authors have proposed the use of a continuous scale but most use specific cut-offs to evaluate the risk of APO, but the proposed range varies widely. The aim, is to evaluate if the Maternal adverse outcome (AO) prediction occurs in a stepwise manner, and if this was the case, which would be the point yielding the highest accuracy.
Methods
This is an observational retrospective cohort study. Singleton pregnancies, between 20 to 40 weeks were selected according the levels of sFlt-1/PlGF; three groups (n = 60 each): High ≥ 655, Intermediate ≥ 85 to < 655 and Low < 85. From hospital records we retrieve data, and outcome, also we quantitate the PE risk. We compared the groups, to determine the clinical utility of the sFlt1/PlGF ratio in prediction of Maternal AO, we used ROC analysis, and to develop a predictive model of Maternal AO a binary multivariate logistic regression was used.
Results
At entry a different degree of severity is observed for groups: High > Intermediate > Low, for: Systolic Blood pressure, Mean Blood pressure, Angiogenic markers, AST, ALT. Also a positive correlation was found between the sFlt-1/PlGF and the afore mentioned variables. We observed a potency order for the Maternal AO, from more to less manifestations High > Intermediate > Low (p < 0,001). sFlt1/PlGF ratio has the highest AUC for predicting Maternal AO than any other single parameter.
Effect of serum vitamin D levels on Helicobacter pylori infection: a Retrospective Study with Real-World Data
Authors: Liu Dan , Ren Li , Zhong Da Peng , Zhang Wei , Li Wen Wen , Liu Jie , Han Chuan
Published: August 2023

Objective
The aim of this study was to determine whether serum vitamin D levels are associated with H. pylori infection and whether low serum vitamin D levels are an independent risk factor for H. pylori infection.
Methods
We conducted a retrospective analysis of a multicenter cohort study from 2017 to 2019. A total of 415 H. pylori + patients and 257 H. pylori- patients aged between 18 and 75 years with both 13C-urea breath test and serum vitamin D level results were included from four hospitals. A questionnaire was used to collect information on potential factors influencing H. pylori infection.
Results
Serum vitamin D levels were significantly lower in the H. pylori + group than in the H. pylori- group (16.7 ± 6.6 ng/ml vs 19.2 ± 8.0 ng/ml, p < 0.05). Using a cutoff value of 20 ng/ml, the H. pylori infection rate was significantly higher in the vitamin D-deficient group (< 20 ng/ml) than in the vitamin D-sufficient group (≥ 20 ng/ml) (66.5% vs 51.0%, p < 0.05). Ordered logistic regression analysis showed that serum vitamin D levels < 20 ng/ml (OR: 1.644, 95% CI: 1.154–2.342), higher education levels (OR: 1.774, 95% CI: 1.483–2.119), household size ≥ 4 (OR: 1.516, 95% CI: 1.081–2.123), and lower household income (OR: 1.508, 95% CI: 1.289–1.766) were independent risk factors for H. pylori infection.
Conclusion
Lower serum vitamin D levels may be associated with an increased risk of H. pylori infection, and lower serum vitamin D levels are an independent risk factor for increasing H. pylori infection rates. Randomized controlled trials are needed to determine whether supplementation with vitamin D can reduce H. pylori infection rates.
Anti-obesity effect of Neoagaro-oligosaccharides with overweight and obese subjects: A 16- week, randomized, double-blind, placebo-controlled clinical trial
Authors: Baek Hyang-Im , Ha Ki-Chan , Park Yu Kyung , Lee Je Hyeon , Kim Eun Joo , Ko Hye-Jeong , Joo Jong Cheon
Published: August 2023

Background
This trial aimed to evaluate the anti-obesity effects and safety of Neoagaro-oligosaccharide (NAOs) in humans in a 16 week, randomized, double-blind, placebo-controlled clinical trial.
Methods
A total of 100 overweight or obese subjects with a body mass index (BMI) of 23 to 34.9 kg/m2 and a body fat percentage of > 25% for males or > 30% for females were enrolled. NAOs or placebo products were administered at 3 g each for 16 weeks. Efficacy and safety biomarkers were measured before and after intervention.
Results
After 16 weeks of intervention, the group administered with NAOs had statistically significant decreases of visceral fat area (VFA), visceral-subcutaneous fat area ratio (VSR), weight, and BMI compared to the placebo group. High-density lipoprotein- cholesterol (HDL-C) was increased in the group administered with NAOs, which showed a significant trend compared to the placebo group. Clinical changes were not observed for any safety biomarkers.
Conclusions
These results suggest that NAOs have a beneficial effect on obesity. Thus, NAOs could be used as an anti-obesity supplement without side effects.
Trial registration:
cris.nih.go.kr: (KCT0006640, 07/10/2021).
Native low-density lipoproteins are priming signals of adipose tissue NLRP3 inflammasome/ interleukin-1β pathway in humans
Authors: Bissonnette Simon , Lamantia Valérie , Ouimet Benjamin , Cyr Yannick , Devaux Marie , Rabasa-Lhoret Remi , Chrétien Michel , Saleh Maya , Faraj May
Published: August 2023

Elevated numbers of atherogenic apoB-lipoproteins (apoB), mostly as low-density lipoproteins (LDL) predict diabetes risk by unclear mechanisms. Upregulation of the innate immunity pathway, the NLRP3 inflammasome/interleukin-1 beta (IL-1β) system, in white adipose tissue (WAT) is implicated in type 2 diabetes (T2D); however, metabolic signals that stimulate it remain unexplored. We hypothesized that LDL stimulate WAT NLRP3 inflammasome. Forty non-diabetic subjects were assessed for risk factors for T2D related to systemic and WAT glucose and fat metabolism before and after 12-week supplementation with omega-3 fatty acids. Regulation of the NLRP3 inflammasome was explored in hip WAT biopsies and macrophages using LDL without/with the inflammasome priming and activation controls (LPS and ATP). Baseline data indicate that LDL induce IL1B-expression and IL-1β-secretion in the presence of ATP in WAT and primary macrophages. Subjects with high-apoB (above median) had higher WAT IL-1β-secretion than subjects with low-apoB independently of covariates. The direction of association of LDL-induced WAT IL-1β-secretion to T2D risk factors was consistently pathological in subjects with high-apoB only. Adjustment for IL-1β-secretion eliminated the association of plasma apoB with T2D risk factors. In conclusion, LDL are priming signals of the human WAT NLRP3 inflammasome/IL-1β pathway. Targeting IL-1β in subjects with high-apoB may prevent T2D.
The Impact of the COVID-19 Pandemic on Public Hospitals Performance Indicators in Iran: an Interrupted Time-series Analysis
Authors: Ranjbar Mohammad , Bazyar Mohammad , Sarkari Omolbanin , Ameri Hossein , Angell Blake , Assefa Yibeltal
Published: August 2023

Background
The Covid-19 pandemic stretched health systems globally including in Iran. Hospital demand and performance was affected both directly and indirectly as a result of the pandemic. Analyzing hospital indicators can provide insights to deal with the consequences and challenges related to various aspects of future pandemics.
Objective
This study aimed to investigate the impact of the Covid-19 pandemic on key performance indicators of public hospitals in Iran.
Methods
We used time-series analysis to examine six key indicators of hospital performance: average length of stay, hospital mortality rate, number of surgeries, hospitalization rate, emergency visits, and bed occupancy rate. Data were extracted from four public hospitals in Yazd at two time intervals, 15 months before and after the outbreak of COVID-19. Data were analysed using interrupted time series analysis models with STATA17.
Results
Average length of stay (p = 0.02) and hospital mortality rate (p < 0.01) increased significantly following the outbreak of COVID-19, while the mean of other indicators such as number of surgeries (p = 0.01), hospitalization rate (p < 0.01), emergency visits (p < 0.01) and bed occupancy rate (p < 0.01) decreased significantly. The Covid-19 pandemic had an immediately reverse significant impact on the level changes of "hospitalization rate", "emergency visits" and "bed occupancy rate" indicators (p < 0.05). although the trend of surgeries indicator was affected significantly (p = 0.01) after the covid-19 outbreak.
Conclusion
We showed significant changes in most hospital indicators after the Covid-19 pandemic, reflecting the effect of this pandemic on the performance of hospitals. Understanding the impact of a pandemic on hospital indicators is necessary for decision-makers to effectively plan an effective pandemic response and to inform resource allocation decisions.
Use of Ilizarov and MIPPO techniques in the treatment of a 20-year infected nonunion of the tibia: a case report
Authors: Niu Zhipeng , Cui Yutao , Ren Guangkai , Wu Dankai
Published: August 2023

Introduction: The management of infected nonunion has always been an orthopedic challenge, and it is more difficult to treat it if it is accompanied by shortening and angulation deformity.
Case report: we present a case of osteomyelitis and infected nonunion of the right tibia with right lower extremity shortening and angular deformities. The Ilizarov technique was applied to treat large segmental bone defects with deformities via simultaneous lengthening of the free bone segment and the broken distal tibia.
Conclusion: Use of the Ilizarov technique in combination with MIPPO can effectively treat bone deformities caused by infected nonunion while reducing the duration of external fixation, protecting against refracture and allowing for early rehabilitation.
Selective feticide in dichorionic diamniotic (DCDA) twins complicated with previable premature rupture of membrane before 24 weeks may be a safe therapeutic alternative to ongoing pregnancy
Authors: Zhu Caixia , Liu Haiyan , Zhu Hui , Huang Linhuan
Published: August 2023

Background To date, there are no clinical guidelines for dichorionic diamniotic (DCDA) twins complicated with previable premature rupture of membrane (PV-ROM) before 24 weeks of gestation. The typical management options including expectant management and/or pregnant termination, induce the risks of fetal mortality and morbidity. Objective To explore the feasibility selective feticide in DCDA twins complicated with PV-ROM. Study Design A Retrospective cohort study, enrolling 28 DCDA twins sufferding from PV-ROM in a terity medical center from Jan 01 2012 to Jan 01 2022. The obstetric outcome was compared between selective feticide group and expectant management group. Results There were 12 cases managed expectantly and 16 underwent selective feticide. More cases suffered from oligohydramnios in expectant management group compared to selective feticide group (P = 0.008). Among 13 cases with ROM of upper sac, the mean gestational age at delivery was (33.9 ± 4.9) weeks in the selective feticide group, which was significantly higher than that in the expectant management (P = 0.038). Five fetuses (83.3%) with selective feticide delivered after 32wks, whereas only one (14.3%) case in expectant management group (P = 0.029). However, in the subgroup with ROM of lower sac, no significant difference of the mean gestation age at delivery between groups and none of cases delivered after 32 weeks. Conclusion There was a trend towards an increase in latency interval in DCDA twins with PV-ROM following selective feticide, compared to that with expectant management. Furthermore, selective feticide in cases with PV-ROM of upper sac has a favorable outcome.
Molluscicidal activity of Piper anisum (Spreg.) Angely Essential Oil and of its 1-butyl-3,4-methylenedioxybenzene Major Compound
Authors: Castilho Rubens Diego de C. , de Carvalho Rosângela R. , Ramos Ygor Jessé , Marques André Mesquita , Moreira Davyson de Lima
Published: August 2023

Schistosomiasis is a historically endemic disease in Brazil, which is caused by the trematode parasiteSchistosoma mansonihosted by the wormBiomphalaria glabratasnails. The searching for new environmental non-toxic active agents forB. glabratacontrol is emerging. Natural products as alternative drug lead can be justified by its low toxicity and environmental sustainability. In this work,Piper anisumessential oil (EO) and its major compound were investigated for molluscicidal activity against snails of the speciesB. glabrata, taking into account the seasonal variation of EO. Leaves ofP. anisumwere collected in different seasons and the EO was obtained by hydrodistillation. Chemical analysis of the EO by Gas Chromatography (GC) coupled to Mass Spectrometer (MS) and GC coupled to Flame Ionization Detector (FID) allowed identification and quantification of the EO compounds, respectively. The EO major compound 1-butyl-3,4-methylenedioxybenzene (BMDB) was also isolated from leafn-hexane extract. The molluscicidal activity was determined by exposing snails to increasing concentrations of the EO and BMDB, and the lethal concentration (LC50) was calculated. The chemical composition of the EO varied between seasons, with higher percentage (> 99%) of BMDB observed in the summer.The results showed molluscicidal activity againstB. glabrata, of all EO samples at 100 µg/mL. The LC50was determined as 35 ppm for BMDB suggesting this compound as an alternative source of biocontrol agent againstB. glabrata.