bluuebunny/crossref_metadata_2025 huggingface dataset:
Antioxidant Potential of Ethanol Extract from Mango Parasite (Dendrophthoe petandra) to Maintain Crude Palm Oil (CPO) Quality
Authors: Susparini Ninik Triayu , Rohmatulloh  , Situmeang Boima , Lailatusholihah Isna , Rohmiyati Siti
Published: August 2022

The present study aimed to determine the effectiveness of adding natural antioxidants from ethanolic extract of mango parasite (Dendrophthoe petandra) to oxidation stability of crude palm oil (CPO) during storage. The parameters tested were levels of free fatty acid (FFA), acid values, and deterioration of bleachability index (DOBI). The antioxidant activity of D. petandra extract obtained was IC50 of 6.369 ppm. Concentrations of D. petandra extract range from 200 to 1000 ppm. Based on the results, the ethanolic extract of D. petandra was able to reduce the FFA and acid value and increase the DOBI compared to the negative control. The lowest FFA levels and acid numbers were obtained from samples with addition of 1000 ppm natural antioxidants with FFA of 4.2% and acid value of 7.4 mg KOH/g, while the DOBI value increased to 1.300.
Organisational citizenship behaviour’s antecedents as predictors of job satisfaction: Empirical evidence from banks in emerging economies
Authors: Maibvisira Gabriel , Mutambara Emmanuel , Mashia Cynthia
Published: August 2022

It was imperative to determine the impact of antecedents of organisational citizenship behaviour of altruism and conscientiousness on job satisfaction in the banking sector since this strategic sector has been experiencing employee job dissatisfaction-related challenges as evidenced by high staff turnover. The reviewed literature focused on the effect of Organ’s (1998) organizational citizenship behavior (OCB) dimensions of altruism and conscientiousness and employee job satisfaction. The article adopted a positivist philosophy and the explanatory research design since it sought to establish cause and effect relationships between the two constructs. The target population was 150 and a sample of 109 participants was used. A simple random sampling technique was used to select study participants. A Likert scale questionnaire was employed to collect data electronically due to the COVID-19 pandemic movement restrictions. The study findings were that both altruism and conscientiousness have a positive and significant impact on job satisfaction in the banking sector. Thus, it was recommended that the banking sector should create workplace environments that foster OCB to enhance employee job satisfaction. This study was critical since banks are a strategic sector (Bonga, Chirenje, & Mugayi, 2019), particularly in emerging economies as providers of start-up and working capital to both public and private organisations.
Exact mathematical Formula that connect 6 dimensionless physical constants
Authors: Pellis Stergios
Published: August 2022

In this paper we will present a new exact
formula for the fine-structure constant in terms of the golden angle,the
relativity factor and the fifth power of the golden mean. A new
interpretation and a very accurate value of the fine-structure constant
has been discovered in terms of the golden radio. We propose the exact
equivalent mathematical expression for the proton to electron mass ratio
using Fibonacci and Lucas numbers and two other exact mathematical
expressions for the proton to electron mass ratio. We present the exact
mathematical expressions that connect the proton to electron mass ratio
and the fine-structure constant. Also we will find a new formula for the
Planck length and a new formula for the Avogadro’s number. First we will
find the beautiful unity formula that connects the gravitational
coupling constant and the fine-structure constant. This equation is the
simple unification of the  gravitational and the electromagnetic
interactions. We will present the exact mathematical formulas that
connect six dimensionless physical constants. The six dimensionless
physical constants are the proton to electron mass ratio μ,the
fine-structure constant α,the ratio Ν1 of the electric force to the
gravitational force between electron and proton,the Avogadro’s number
NA,the gravitational coupling constant αG of the electron and the
gravitational coupling constant αG(p) of the proton. Also we will find a
new formula for the gravitational constant G. Finally we will be
presented the formula for the cosmological constant Λ. This unity
formula is a simple analogy between atomic physics and cosmology.  All
these equations are simple,elegant and symmetrical in a great physical
meaning.
Rational design engineering of a thermostable α- carbonic anhydrase from Sulfurihydrogenibium yellowstonense to improve its thermostability for industrial applications
Authors: Ghaedizadeh Shima , Zeinali Majid , Dabirmanesh Bahareh , Rasekh Behnam , khajeh khosro , Banaei-Moghaddam Ali Mohammad
Published: August 2022

Carbon dioxide (CO2) capture and storage (CCS) processes could benefit
from thermostable carbonic anhydrases (CAs), which can significantly
increase the rate of CO2 absorption into solvents. Since conventional
CO2 absorption techniques are usually performed under high-temperature
conditions in industrial plants, implementing highly thermostable CAs is
very important to introduce a robust and economical process. The present
study employed a combination of in silico tools to rationally engineer a
thermostable CA (SspCA) originating from a thermostable bacterium
Sulfurihydrogenibium yellowstonense. Based on the results, while the
general folding of the enzyme and its catalytic efficiency was retained
in the K100G mutant, the melting temperature increased by 3°C, and the
CO2 hydration activity half-life at 85°C increased by two times.
Molecular dynamics (MD) simulations were performed to determine the
underlying causes of the thermostability improvement. The K100G mutation
was shown to cause a reduction in protein local flexibility mainly by
confining the flexible parts due to rearrangement of salt bridges and
hydrogen interactions network. In sum, while strengthening the
importance of rational design in thermostable enzymes, the present study
showed the capability of merely one rationally-designed mutation which
indirectly resulted in CA thermostability improvement by exerting local
structural rigidification in its neighboring part.
Learning curve and initial experience for left bundle branch area pacing with standard stylet-driven pacing leads: comparison with conventional right ventricular pacing
Authors: Kim Tae-Hoon , Yu Ga-In , Yu Hee Tae , Joung Boyoung , Pak Hui-Nam , Lee Moon-Hyoung
Published: August 2022

Introduction: His bundle pacing (HBP) was developed as a
physiological conduction system pacing to complement the problem of
conventional right ventricular pacing (RVP) related to dyssynchrony.
Recently, left bundle branch area pacing (LBBAP), which overcomes the
shortcomings of HBP, has been implemented. Most researches on initial
experiences with LBBAP have reported that it was achieved through a
lumen-less pacing lead (LLL) with a fixed helix design; however, there
are situations in which LLL cannot be used. The purpose of present
research is to evaluate the initial experience and learning curve of
LBBAP using a standard stylet-driven lead with an extendable helix
design. Methods: 265 patients who underwent LBBAP or
conventional RVP performed by operators without previous LBBAP
experience at Yonsei University Severance Hospital in Korea between
December 2020 and October 2021 were enrolled. LBBAP was performed using
a stylet‐driven pacing lead with an extendable helix. The learning curve
was evaluated by analyzing fluoroscopy and procedure times.
Results: LBBAP was successful in 65 of 69 (94.2%) patients
during the observation period. In 65 patients who underwent LBBAP, mean
fluoroscopy and procedural times were 17.1 ± 17.2 minutes and 64.2 ±
33.5 minutes, respectively. The learning curve for achieving LBBAP
plateaued after the 24th case, with a gradually shortened in procedure
time. Conclusion: During the initial experience with LBBAP,
fluoroscopy and procedural times improved with increasing operator
experience. For operators who were experienced in cardiac pacemaker
implantation, the steepest part of the learning curve was over the first
20-25 cases.
Improving Fraud Performance with a Different Perspective
Authors: Chui Lawrence C. , Curtis Mary B. , Pike Byron J.
Published: August 2022

Chui, Curtis, and Pike (2022) find that auditors encouraged to take a forensic specialist's perspective provide a more effective and efficient risk response in varying fraud risk environments than with their traditional mindset. The study provides evidence that auditors can adopt the forensic perspective which focuses on fraud detection, while maintaining their typical audit roles and responsibilities. We summarize their key findings and discuss practical implications and actionable suggestions for audit practitioners. These insights suggest a potential low-cost mechanism to improve auditors' fraud risk assessments and subsequent risk responses.
Rising Hemoglobin A1c in the Non-Diabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests
Authors: Vehik Kendra , Boulware David , Killian Michael , Rewers Marian , McIndoe Richard , Toppari Jorma , Lernmark Ake , Akolkar Beena , Ziegler Anette-Gabriele , Rodriguez Henry , Schatz Desmond A , P. Krischer Jeffrey , Hagopian William A. , Group TrialNet Study , Group TEDDY Study
Published: August 2022

  

Objective: Biomarkers predicting risk of type 1 diabetes (Stage 3) among children with islet autoantibodies are greatly needed to prevent DKA and facilitate prevention therapies. 

Research Design and Methods: Children in the prospective TEDDY study (n=707) with confirmed diabetes-associated autoantibodies (GADA, IA-2A and/or IAA) and ≥2 HbA1c measurements were followed to diabetes or median age 11.1 years. Once confirmed autoantibody positive, HbA1c was measured quarterly. Cox models and receiver operative characteristic (ROC) analyses revealed the prognostic utility for risk of Stage 3 on a relative HbA1c increase from the baseline visit or an OGTT 2-hr plasma glucose (2-hPG). This HbA1c approach was then validated in the TrialNet Pathway to Prevention study (n=1190).

Results: A 10% relative HbA1c increase from baseline best marked increased risk of Stage 3 in TEDDY (74% sensitive; 88% specific). Significant predictors of risk for HbA1c change were age and HbA1c at baseline test, genetic sex, maximum number of autoantibodies and maximum rate of HbA1c increase by time of change. The multivariable model featuring a HbA1c >10% increase and these additional factors revealed increased risk of Stage 3 in TEDDY (HR=12.74, 95%CI 8.7-18.6, p<0.0001) and TrialNet (HR=5.09, 95%CI 3.3-7.9, p<0.0001). Furthermore, the composite model using HbA1c >10% increase performed similarly to an OGTT 2-hPG composite model (TEDDY AUC=0.88 and 0.85, respectively) and to the HbA1c model in TrialNet (AUC=0.82).

Conclusion: An increase of >10% in HbA1c from baseline is as informative as OGTT 2-hPG in predicting risk of Stage 3 in youth with genetic risk and diabetes-associated autoantibodies.
Corrigendum: Dermatofibrosarcoma Protuberans Re-excision and Recurrence Rates in the Netherlands Between 1989 and 2016
Authors: Van Lee Charlotte B. , Kan Wilner Christopher , Gran Sonia , Mooyaart Antien , Mureau Marc A.M. , Williams Hywel C. , Matin Rubeta , Van den Bos Renate , Hollestein Loes M.
Published: August 2022

Abstract is missing (Corrigendum)
FOREIGN LANGUAGE TEACHER’S PROFESSIONAL COMPETENCE IN FORMING FUTURE AGRARIANS’ CREATIVE THINKING
Authors: Kravets Ruslan
Published: August 2022

The article is devoted to a foreign language teacher’s professional competence in forming future agrarian’s creative thinking. It reveals the essence and the structure of future agrarians’ creative thinking as an integrative unity of cognitive processes and individual intellectual skills, which determine flexibility, originality and productivity of professional task solving, have been elucidated. Its components (motivation-value, cognitive, activity-creative), indicators, levels and pedagogical conditions (development of intrinsic motivation on the basis of a dialogical approach, activation of independent creatively-exploratory educational work by means of problem-oriented teaching, providing creative cooperation among the subjects of a pedagogical process by using methods of interactive teaching), which enable effective forming the creative thinking in the process of professional training, have been defined. The methodology of sequential forming of future agrarians’ creative thinking has been developed. The functionalstructural model of forming future agrarian’s creative thinking has been experimentally verified. The results have been confirmed by statistical changes in the levels of the creative thinking in the experimental group compared to the control one.
THE ARTIST MODEL IN CULTURAL INTERPRETATION
Authors: Lifintseva Olena
Published: August 2022

The article reveals the approaches of scientists to understand the phenomenon of the artist in the modern cultural space. The study considers the definitions of the artist model, as well as their essence. The article proposes the author's definition of the term “Аrtist” in a cultural interpretation. The existence of significant indicators of creatively gifted personality, which are manifested in creative abilities, psychological qualities and value orientations, indicating the high level of the artist in the communicative space of culture. The study is based on general scientific theoretical methods of analysis, which allowed us to work out and explore the concepts of scientists in the formation of the artist model. It has been proven that the artist as a unique creatively gifted personality is the bearer of the initiative principle, the creator of spiritual values and artifacts of culture, which seeks self-esteem in the processes of cultural formation to achieve maximum correspondence in art and culture.
ENVIRONMENTAL IMPERATIVE IN THE CONTEXT OF GLOBALIZATION PROCESSES: MODERN CHALLENGES
Authors: Korchak Nataliia , Kozachenko Tatiana
Published: August 2022

Today, scientists and public figures are increasingly leaning towards the idea that the new model of globalization characterized by multifaceted nature should be formed in the world. In this context, the criterion for measuring the success of states should not be the desire for high economic growth rates but the possibility of transition to sustainable development models, which pay special attention to environmental globalization. The purpose of the article is a scientific and practical substantiation of the essence, role, and significance of environmental imperative, which will improve the mechanisms and tools for implementing environmental policy amidst globalization processes. Methods used in the study comprise general scientific ones (analysis and synthesis, induction and deduction), methods of theoretical research (from abstract to concrete), and historical method. In terms of the analysis of potential environmental threats and vulnerability, a risk-based approach and world-systems theory were applied. The theoreticalmethodological analysis of the essence of the environmental imperative amidst globalization processes was presented. The reality and scale of today’s environmental threats were proved. The authors formulated a conceptual vision of the scenario of influence events as separate factors that destroy the environment of the whole planet and the danger of nuclear conflict, as well as the synergistic effect of ensuing consequences. The mechanisms and the ability of the country and the world to counter probable environmental threats through identifying their potential vulnerabilities are substantiated.
BASIC CONCEPTS OF STATE GOVERNANCE OF DEPARTMENTAL MEDICINE IN UKRAINE
Authors: Sukhanova Yana , Kryzyna Natalia
Published: August 2022

The article is devoted to the study of the categorical-conceptual apparatus of state governance in the field of health care and departmental medicine in Ukraine. The article highlights the definitions, principles of functioning of the health care sector, state governance of the health care sector and state governance of departmental medicine, which is a functional entity that is able to unify approaches to medical care, its availability and quality. The study of the problem of state governance of departmental medicine in Ukraine in wartime necessitated the analysis of scientific interpretations of the basic concepts: “medicine”, ”departmental medicine”, ”health care», «state governance”, “state governancein the field of health care “I”. The current state of the medical industry in Ukraine is characterized by low efficiency of available financial and economic, logistical and human resources, slow pace of change in the implementation of innovative diagnostic methods and technologies and lack of understanding of standards and indicators of quality and management in providing medical services to all patients. departmental health care. The Sustainable Development Strategy “Ukraine – 2030” envisages the implementation of reforms and programs of state development and reform of the health care system: creation of a patient-oriented system capable of providing medical care for all citizens of Ukraine at the level of developed European countries; increasing the personal responsibility of citizens for their own health (Strategy-of-sustainable-development-of-Ukraine-until-2030, 2017). Which prompted the study of the problem of state governance of Ukrainians departmental medicine.
I nærkamp med Notefienden: skam, myndiggjøring og performativ læringa
Authors: Schøien Kristin Solli , Bandlien Bjørn-Terje , Østern Anna-Lena
Published: August 2022

Denne studien er et bidrag til performativ musikkforskning, med et pedagogisk utgangspunkt. Metodologisk utforsker forfatterne eksperimentelle innganger til musikkforskning gjennom performance-skriving og collageteknikk. Artikkelen er en studie av på hvilke måter en komponists nærkamp med notefienden, vanskene med å lese og skrive noter, får agens i hennes komposisjon og formidling av musikk. Musikken i studien er komponert til tekster av den norske dikteren Herman Wildenvey, og studien gjør nedslag i tre tidsperioder med et spenn på tre desennier. Gjennom performance-skriving viser forfatterne hvordan notelesingsvanskene både hindrer og utfordrer det kreative arbeidet, og gjennom diffraktiv analyse undersøkes notefiendens agens i tre diffraksjoner: (1) når komponisten skaper melodiene til Wildenveys lyrikk, (2) når sangene blir urfremført og lydfestet, og (3) når komponisten og pianisten performativt utforsker en av sangene i samspill. Studien viser at notelesingsvanskene får betydning for komponistens valg av musikkstil, selvforståelse og kroppslige tilstedeværelse i musikken, og for det musiker-metaspråket som komponist og pianist utvikler i samspillsituasjonen. Studien avdekker gjennom et postperspektiv, inspirert av Barad, hvordan erfaringer fra en tidlig musikkpedagogisk praksis setter spor som har virkning i nåtid. Artikkelen gir også et eksempel på hvordan performativ læring er agent for endring og myndiggjøring i et livslangt perspektiv.
Post-approaches to education and the arts: Putting theories to work in arts educational practices
Authors: Jusslin Sofia , Bodén Linnea , Magnusson Lena O , Østern Tone Pernille
Published: August 2022

This special issue explores how post-approaches to education and the arts emphasize learning, teaching, and knowledge-production in the arts as performative processes of becoming in-between humans and other materialities in a more-than-human world. Moreover, the articles included in the special issue reveal that such an endeavor calls for new ways of doing research through post-qualitative and practice-led research methodologies.
Vitamin D Deficiency in Elderly Saudi Patients with Type 2 Diabetes Mellitus
Authors: SJ Aljabri Khalid
Published: August 2022

Introduction: Vitamin D deficiency and type 2 diabetes mellitus (T2DM) remain major health problems. We conducted a cross sectional study to investigate the prevalence vitamin D deficiency in elderly patients with T2DM. Method: A cross-sectional single center study was conducted in 1622 patients 60 years or more with T2DM attended the Diabetes Centre at King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia between January 2018 and December 2018. The serum concentration of 25-hydroxyvitamin D (25-OHD) and HbA1c were measured. Results: There were 1622 patients with T2DM, 28.3% male and 71.7% female. Vitamin D deficiency was found in 37.6%. Moreover, vitamin D deficiency was significantly more prevalent among females than males (61.6% vs. 38.4% respectively, p<0.0001). In addition, Vitamin D deficient patients were statistically significant younger than non-vitamin D deficient (69.0±7.3 vs. 70.7±8.2 respectively, p<0.0001). Vitamin D deficient patients have statistically significant higher HbA1c than non-vitamin D deficient (8.3±1.9 vs. 7.4 ±1.6 respectively, p<0.0001). The mean 25-OHD was statistically significant lower in the age 60-69 years patients compared to ≥70 years patients (61.6 vs. 65.3 nmol/l respectively, p=0.02). There was higher frequency of vitamin D deficiency found in the age 60-69 years patients compared to ≥70 years patients with males statistically significant most frequent than females in the 60-69 years compared to ≥70 years patients. 25-OHD concentration was significantly correlated with age and HbA1c. Regression analysis of odd ratio of risk factors for patients with vitamin D deficiency showed that female gender, age and HbA1c were statistically significant associated with vitamin D deficiency. Conclusions: The prevalence of vitamin D deficiency in elderly patients with T2DM is high and that more females with T2DM are affected than males.
Effects on Metabolic Parameters of Addition of SGLT‐2 Inhibitors on Patients with Type2 Diabetes Inadequately Controlled with DPP‐IV Inhibitors and Metformin
Authors: Majumder Anirban
Published: August 2022

Background: Practice guidelines are open regarding choice of therapy after metformin. The second line agent’s insulin (INS), sulphonylureas (SU) and thiazolidinediones (TZD) may cause either hypoglycaemia or weight gain. Dipeptidyl peptidase‐IV (DPP-4) inhibitors are unlikely to produce that. Sodium‐glucose transporter‐2 (SGLT -2) inhibitors are newer agents with the advantage of weight loss. Indian data regarding combination therapy with Metformin withDPP-4 inhibitors plus SGLT-2 inhibitors arescanty; hence this study is relevant .Moreover the number of patients studied, duration of study, study variables and effects of three SGLT-2inhibitors were analyzed separately. Objectives: To study the glycaemic and other metabolic parameters after treatment with SGLT‐2 inhibitors-canagliflozin or, dapagliflozin, or, empagliflozin in type 2 Diabetes (T2DM) patient inadequately controlled (HbA1c >7.5%) with DPP-4 inhibitors plus metformin. Methodology: Data of 101 T2DM patients inadequately controlled (HbA1c> 7.5%) with DPP-4 inhibitors plus metformin who were prescribed canagliflozin 100 mg or, dapagliflozin 5 or 10 mg, or empagliflozin 10 mg or 25 mg once daily with mean follow‐up duration of 23 weeks were analyzed. Subjects receiving INS, SU and TZD were excluded from analysis. Changes in weight, blood pressure, glycaemia, lipids, renal and hepatic parameters were studied. Subgroup analyses were done to see effects of three SGLT‐2 inhibitors. Results: Results showed that addition of SGLT-2 inhibitors produced favourable effects on all metabolic parameters studied. Conclusion: Our study shows that addition of SGLT2 inhibitors on existing therapy with DPP-4 inhibitors and metformin produces favourable effects on metabolic parameters with the advantage of weight loss and without producing major hypoglycaemic events.
Addressing Diabetes in Global Communities through the Practical Implementation of Lifestyle Education: Lessons Learned from the Pacific Islands
Authors: Clarke Camille
Published: August 2022

It is well known that chronic diseases are strongly liked to poor lifestyle practices. These conditions are especially striking among low income, minority communities who bear a disproportionate burden of disease. Though practice guidelines for chronic disease prevention and management recommend that treatment begin with evidence-based lifestyle medicine, many physicians cite inadequate confidence and lack of knowledge and skill as the major barriers to counseling patients about lifestyle interventions. Furthermore, time constraints, clinical and administrative demands often make it challenging for primary care providers to deliver appropriate lifestyle related recommendations. Current changes in the healthcare climate and reimbursement structure, however, demand that we rethink current healthcare delivery models and prioritize preventive and lifestyle interventions so that sustainable positive health outcomes can be attained especially among vulnerable communities. Lifestyle medicine, defined as the evidence-based therapeutic approach to prevent, treat and reverse lifestyle-related chronic diseases. It offers promise in achieving this goal through community based offering and primary care integration utilizing multidisciplinary teams. Lifestyle education, among minority populations, however, requires thoughtful cultural considerations and adaptations. This article highlights strategies learned from international work among Pacific Islanders who suffer from a disproportionate burden of noncommunicable diseases; and offers recommendations on how diverse populations can be positively engaged to curb the rising diabetes epidemic both locally and internationally.
The Perception of Medical Students Regarding the Approach to Obesity as a Priority
Authors: Ribeiro Jonathan Nícolas dos Santos
Published: August 2022

Obesity is a chronic disease and increasing incidence, studies reveal that treating and preventing seven of the top 10 killer diseases. Although much is published about the theme, there is a degree of ignorance on the part of the medical community about the treatment of obesity and its impact on chronic diseases. The present work investigated the medical student's view of the impact of obesity as a priority when dealing with related comorbidities. A survey was conducted, assessing the medical student's perception of the patient with obesity. Of a total of 377 students, 267 (70.82%) stated that other diseases such as diabetes and hypertension should be prioritized when evaluating the obese patient, while 110 (29.17%) stated that obesity should be prioritized. Based on the outcomes presented, it can be concluded that the perception of medical students regarding obesity approach still shows a predominance opinions that other diseases should be a priority over obesity.
Hyperlipidimia, Hyperleptinemia and Insulin Resistance Intercorrelation with Obesity
Authors: Chandra Nimai Chand
Published: August 2022

The present study has shown a parallel increase of triacylglycerol, cholesterol, and low density lipoprotein (LDL) along with an increase in body mass and BMI of human obese subjects. Conversely a fall in HDL concentration was observed. Plasma leptin level increased proportionately with increase of body weight as obesity advanced from obese to morbid type. A positive correlation was observed between leptin and insulin concentrations in obese subjects. A parallel increase of plasma glucose concentration was followed with decreased expression of insulin receptor, measured in adipose tissue, with the progress of obesity. The decreased insulin receptor concentration might be the reason for seen insulin resistance and increased insulin level which marked the positive correlation with associated liptin level in obese subjects.
Characterization of Adults with Initial Diagnosis of Type 2 Diabetes Mellitus in Peru
Authors: Rocca Jesus
Published: August 2022

Aims: To describe the characteristics of adults with an initial diagnosis of type 2 diabetes mellitus (T2D) in multiple regions of Peru. Methods: Descriptive case series study performed at 26 centers. Subjects age >20 years with T2D debut were included. Exclusion criteria were pregnancy, use of drugs known to alter glucose metabolism, and having renal, hepatic, respiratory, or cardiac insufficiency. Results: 581 subjects were enrolled, 48.9% were female, mean age was 53.2 years (SD ± 12.8). Mean weight was 77.3 kg (SD +/- 16.6), 39.2% were overweight and 45.1% were obese. Mean waist circumference was 100.6 cm (SD +/- 13.1). Mean blood glucose and HbA1c were 249.4 mg/dl and 8.9%, respectively. Subjects from Lima and the northern sites had higher levels of glucose and HbA1c. Subjects from high altitude sites had higher rates of fatty liver and lower levels of LDL-c and total cholesterol. Younger patients tended to have more metabolic alterations. Conclusions: This study is among the first to describe characteristics of adults with T2D debut in Peru. People from Lima and the northern provinces as well as those diagnosed at an early age seem to be at higher risk.
Contribution to the Management of Abnormal Insulin Secretion in Diabetes of Pregnancy using Antidiabetic Medicinal Plants in Cameroon
Authors: Nolé Tsabang
Published: August 2022

Abnormal insulin secretion occurs during hypoinsulinism and hyperinsulinism. Hypoinsulinism is absolute or relative insulin insufficiency which produces a very common clinical sickness called diabetes mellitus. Hyperinsulinism designs an overhead normal level of insulin in a patient’s blood. Hyperinsulinism is the disproportionate production of insulin by tumors of the pancreatic β cells. Patients who suffer from hyperinsulinism disorder undergo hypoglycemic crises, weakness, intense perspiring, and vertigo. This alteration is not known by people of surrounding areas of developing countries like Cameroon. To identify previous work used to write this article a systematical search was done using engines including: “Antidiabetic plants help to control the hyperinsulism in pregnant diabetic women or animals” and “Toxicity of a given recorded plant name” used to verify the harmlessness of recorded plants. Plants that caught our attention are plants already used by hinterlands diabetic women in Cameroon. An increase in insulin secretion by fetal pancreas and placenta coincides with an increased number of insulin-producing B-cells to lower glucose levels in the bloodstream and promote the storage of glucose in adipose and muscle tissue, liver and other body tissues. It was demonstrated that insulin released from the liver stimulate also glucose uptake and naturally maternal insulin does not cross the placenta. Well controlled healthy pregnant women have a good chance of having a normal pregnancy and birth. But in developing countries diabetes is not generally well controlled during pregnancy in many hinterland areas and still affecting maternal and baby health. At the time of birth newborns diabetic mothers are still often larger, and after birth their vagina is harder and may upsurge the risk for nerve injuries and other trauma during birth. Also many risk including birth defect of the lower spine, birth defect of the brain, and limb result from pre-existing diabetes. Screening of all pregnancy for insulin resistance and early intervention may help to reduce these connected complications. Do antidiabetic plants more economical and available, taken by indigenous gestational diabetics control GDM?
Risk Factors for Methicillin Resistant Staphylococcus aureus (MRSA) from Diabetes Patients with Foot Ulcers (DFU) in a Tertiary Hospital
Authors: Nnachetam Unegbu Valentine
Published: August 2022

Diabetic foot ulcer (DFU) is a major complication of diabetes mellitus. Risk of MRSA should be considered in selecting empirical antibiotics. This study was aimed to determine the Risk factors of Methicillin Resistant Staphylococcus aureus (MRSA) from Diabetes patients with foot ulcers (DFU). A total of 204 patients with diabetic foot were included in the study. Data collected using a pre-designed questionnaire included patient characteristics and medical history to determine risk factors for developing an MRSA infection in the foot. Specimens were obtained by scraping the ulcer base or the deep portion of the wound edge with a sterile curette, and were promptly sent to the laboratory for culture and identification. The prevalence of MRSA in DFU patients was 22.1%. Male patients with DFU were more infected with MRSA 26(12.7%) than females 19(9.3%) with statistical significance (p < 0.04). The age group 41 – 60 years had the highest prevalence of 27(13.2%) with statistically significance (p < 0.03). Farmers and DFU patients of 6 – 10 years had the highest prevalence of 20(9.8%) and 22(10.8%) without statistical significance. Risk factors were all significantly associated to MRSA colonization of diabetic foot ulcers and includes patients who had Type 2 diabetes for 1 – 5 years, and fasting blood sugar greater than >126, patients who smoked and drank for more than 10 years, and patients with body mass >30kg/m2. The prevalence of MRSA in DFU patients was 22.1% which was high. Risk factors were all statiatically associated to MRSA colonization of diabetic foot ulcers. The results from this study will guide healthcare workers on how to educate the patients in the study environment on the possible risk factors contributing to the colonization of MRSA in diabetic foot ulcers and the use of antibiotic therapy to eliminate MRSA from colonized wounds.
TANDA TASHIH DAN INDUSTRIALISASI MUSHAF AL-QUR’AN
Authors: Kholiq Hasan Moh. Abdul , Daroini Hikmatul Jazila
Published: August 2022

This paper attempt to answer how a Mushaf publisher obtained the letter "Tanda Tashih"? And how is the influence of the letter "Tanda Tashih" Mushaf on consumer confidence in the industrialization of the Mushaf al-Qur'an ?. This field research used a qualitative descriptive method with a phenomenological approach. The results showed that the "Lajnah Pentashihan Mushaf Al-Qur'an (LPMQ)" Ministry of Religion of the Republic of Indonesia has established strict procedures and accountability in issuing the letter "Tanda Tashih" as a legal permit for the circulation of Mushaf in Indonesia. The letter "Tanda Tashih"  or Circular Permit can minimize various errors in publishing the Mushaf al-Qur ʻan. All companies publishing al-Qur'an in  Indonesian is obliged to comply with and follow the procedures and regulations for publishing al-Qur'an that have been established by the LPMA. The aim is to guarantee the correctness of the Al-Quran manuscripts and to give consumers a sense of trust. Surat Tanda Tashih has a far-reaching and profound influence on consumers' confidence in buying the Mushaf of the Qur'an. The existence of the Surat Tashih letter has become one of the most important factors in the development of the industrialization of the Mushaf al-Qur ʻan in Indonesia.
PEMIKIRAN PENDIDIKAN TAUHID AHMAD AS-SURKATI DAN IMPLEMENTASINYA TERHADAP PENDIDIKAN DI AL-IRSYAD
Authors: Shobron Sudarno , Widyantoro Yuda Dwi
Published: August 2022

The purpose of this study is to describe the thoughts of Sheikh Ahmad As Surkati about monotheism education and the implementation of Sheikh Ahmad As Surkati's thoughts about monotheism education at Al Irsyad Surakarta Junior High School, so that it can be used as a material for consideration in order to improve the quality of conducting monotheism education. This study uses a qualitative type and includes field research (field research), because the data is fully excavated from the field. This study uses an implementative philosophical approach. Sources of data in this study were obtained directly from field research from a number of sources concerning information about the implementation of the thoughts of Sheikh Ahmad As Surkati about monotheism education at the Middle School Al Irsyad Surakarta. Data collection techniques used in this study were through observation, interviews, and documentation. Data analysis was performed descriptively using the inductive method. The results showed that the thoughts of Shaykh Ahmad As Surkati about monotheism education included three main things, ijtihad and taqlid, sunnah and bid'ah and grave pilgrimage and bertawasul to the prophets and saints. The implementation of Shaykh Ahmad As Surkati's thoughts on monotheism education at Al Irsyad Surakarta Junior High School was carried out through habituation and inclusion in the subject matter of Fiqh.
KEARIFAN LOKAL SEBAGAI SARANA PENDIDIKAN ISLAM MULTIKULTURAL: STUDI HIDDEN CURRICULUM DI PONPES NURUL HUDA SRAGEN
Authors: Afiah Siti , Asy'arie Musa , Aryani Sekar Ayu
Published: August 2022

Penelitian ini bertujuan untuk mengetahui bagaimana kearifan lokal dipraktekkan sebagai sarana pendidikan Islam, bagaimana hidden curriculum berimplikasi terhadap perilaku santri serta berperan dalam penguatan karakter multikultural. Menggunakan metode kualitatif yang bersifat eksploratif dengan fokus  holistik yaitu place, actor dan activity. Teknik pengumpulan data dilakukan dengan observasi, wawancara, dan dokumentasi.  Sumber data sesuai  purpossive sampling adalah semua unsur personalia yang terlibat dalam kegiatan  pondok pesantren. Hasil penelitian diantaranya (1) kearifan lokal sebagai sarana pendidikan Islam dipraktekkan dengan menyampaikan nilai-nilai Islam melalui kegiatan budaya lokal seperti pagelaran wayang kulit, filsafat Jawa dalam kemasan bahasa yang sederhana, arsitektur masjid model Jawa yang mengutamakan keterbukaan dan kebersamaan serta upaya pelestarian budaya tradisional yang berakar pada rasa syukur kepada Tuhan. (2) Hidden curriculum berimplikasi terhadap perilaku santri  melalui wejangan dan tausiah pimpinan pondok. (3) Peranan hidden curriculum dalam penguatan karakter multikultural terlihat dari softskill santri yang menunjukkan kemampuan membangun sikap toleransi, kebersamaan dan kesetaraan.
IMPLEMENTASI BLENDED LEARNING DALAM PEMBELAJARAN PAI DI MAN 4 PASAMAN BARAT PADA MASA COVID-19
Authors: Tasniwati Tasniwati
Published: August 2022

Madrasahs ranging from ibtidaiyah level to Aliyah have Islamic religious education curriculum, in accordance with the results of readings on various literature and initial observations made in MAN 4 West Pasaman islamic religious education learning is still faced with complex problems, the right logic for this is normal conditions are still difficult especially covid-19 conditions. The purpose of this research is to describe how blended learning is implemented in PAI learning during covid-19, this research method is descriptive qualitative, the data source used is the head of madrasah, deputy head, teacher of PAI field and some students selected purvosiv, to get data from informants used techniques that are prevalent in qualitative research namely observation, interview and documentation studies. The result of this study is, learning planning using blended learning there are differences in planning during and offline, the implementation of PAI learning with blended learning during covid-19 in MAN 4 Pasaman is done by dividing the learning ship based on odd weeks and odd classes. Third, evaluation of PAI learning with Blended learning is done by utilizing google form and video practice made by students.
ISLAMIC CHARACTER VALUES IN ECOLOGICAL EDUCATION PRACTICES AT SANGGAR ANAK ALAM (SALAM) NITIPTAYAN BANTUL
Authors: Anwiyah Rifatul , Rahmatullah Azam Syukur , Fauzan Aris
Published: August 2022

The purpose of this study is to analyze the values of Islamic character in the practice of ecological education in the non-formal school of Sanggar Anak Alam (SALAM), Nitiptayan, Bantul by examining the problem how the environmental practices carried out by the Nitiprayan Bantul Nature Studio? the ecological practices carried out by Sanggar Anak Alam?, how is the process of instilling Islamic character values in environmental practices at Sanggar Anak Alam?. based on the results of the data obtained, namely the importance of character education of Sanggar Anak Alam have a strong relationship with the substance of values in Islamic teachings which are reflected in fundamental aspects and give meaning to Islam. This study describes the development of the environment is to maintain the balance of nature and the balance of the social atmosphere. This research also confirms that the community, which also gives meaning to the relationship of spirituality with a deeper appreciation of religion, tends to have a deep concern for environmental issues. The character education process from this ecological practice can be shown from the learning cycle, namely awareness, habituation, actual training, example and reflection.Tujuan penelitian ini adalah menganalisis nilai – nilai karakter Islami dalam praktik pendidikan ekologi di sekolah non – formal Sanggar Anak Alam (SALAM), Nitiptayan, Bantul dengan mengkaji permasalahnnya bagaimana praktik ekologi yang dilakukan Sanggar Alam Nitiprayan Bantul ?, apa nilai karakter Islam yang terkandung pada praktik ekologi yang dilakukan oleh Sanggar Anak Alam ?, bagaimana proses penanaman nilai – nilai karakter Islam pada praktik ekologi di Sanggar Anak Alam ?.  berdasarkan hasil data yang didapatkan yaitu nilai – nilai pendidikan karakter Sanggar Anak Alam memiliki hubungan kuat dengan subtansi nilai dalam ajaran Islam yang tercermin dalam aspek – aspek yang nyata dan memberikan makna Islam. Penelitian ini digambarkan pengembangan lingkungan hidup adalah terpelihara keseimbangan alam dan keseimbangan lingkungan hidup sosial. Riset ini juga memberkan afirmasi bahwa komunitas yang juga memberikan makna pada hubungan spiritualitas dengan lebih menghayati agama cenderung punya kepedulian yang tinggi pada masalah lingkungan hidup. Proses pendidikan karakter dari praktik ekologi ini dapat ditunjukan dari siklus pemebalajaran yaitu penyadaran, pembiasaan, praktik nyata, keteladanan dan refleksi.
THE CONCEPT OF WAQF IN INDONESIAN LAW: ITS HISTORY AND DEVELOPMENT مفهوم الوقف في القانون الإندونيسي: تاريخه وتطوره
Authors: Kuncoro Ardhika Wahyu , Urrosidin Mohammad Syifa , Husni Ahmad Bin Muhammad
Published: August 2022

: يهدف هذا البحث إلى كشف العلاقة بين نظرية الوقف المتفق عليها عند جمهور الفقهاء وبين ما يكون في القانون الوقفي الإندونيسي. وهذه القضية مثيرة للإهتمام، لأن التآزر بين القانون الوضعي وارتباطه بالشريعة الإسلامية مهم لضمان صحة الأساس القانوني الذي سيتم تطبيقه في عامة الناس، وخاصة في إندونيسيا كأكبر الدول عددا للمسلمين في العالم. وسيتناول البحث مفهوم الوقف في القانون الإندونيسي الماضي والحالي وبيان تطور فقه الوقف فيه. وقد استخدم الباحث ثلاثة مناهج؛ هي: الاستقرائي والتحليلي والمنهج المقارن. ومن أهم النتائج التي توصل إليها الباحث: إن مفهوم الوقف في إندونيسيا يختلف قبل تشريع القانون رقم ٤١ عام ٢٠٠٤م وبعدها، وتشمل التطورات القانونية الناتجة على تطوير المحاولات الإدارية، وتطوير نوعية العين الموقوفة (الموقوف به)، وتطوير إدارة ممتلكات الوقف.
HUKUM BERJENGGOT DALAM ISLAM: KAJIAN TERHADAP FENOMENA JENGGOT SEBAGAI FASHION DALAM TEORI SOSIAL
Authors: Yudisman Septevan Nanda
Published: August 2022

Beards are natural for Adam, like mustaches or beards, as if beards always refer to the impression of terrorists or radical Islamic groups. In many cases in the real world, in various parts of the world, beard discrimination is a serious problem. beard (lihyah) is the name of the hair that grows on both cheeks and chin. So, all the hair that grows on the chin, under the two lower jawbones, cheeks, and sides of the cheeks is called lihyah (beard) except the mustache. Keeping and leaving the beard is also Islamic law and the sunnah of the Prophet sallallaahu 'alaihi wa sallam. Men's beard fashion on this one is currently growing and in great demand, beards are intended as a sign of men's macho. This is a very plausible reason. Men do have hair hormones and facial hair, which since ancient times has been used as a means of showing good looks, maturity, and male charm in the eyes of women.Beards are not just an order from religious law, but more than that, maintaining a beard is beneficial for health. Maintaining a beard is scientifically proven to be healthy. Especially when it comes to shaving the beard, there are elements that go against nature and resemble women. Because the beard is a symbol of the perfection of men and a sign that distinguishes them from women.Jenggot adalah  hal alami bagi kaum Adam, layaknya kumis atau jambang, Seakan jenggot selalu pasti merujuk pada kesan teroris atau kelompok Islam radikal.Banyak kasus di dunia nyata, di berbagai belahan dunia, diskriminasi jenggot ini menjadi masalah yang serius. jenggot (lihyah) adalah nama rambut yang tumbuh pada kedua pipi dan dagu. Jadi, semua rambut yang tumbuh pada dagu, di bawah dua tulang rahang bawah, pipi, dan sisi-sisi pipi disebut lihyah(jenggot) kecuali kumis. Memelihara dan membiarkan jenggot juga merupakan syariat Islam dan sunnah Nabi shallallahu ‘alaihi wa sallam. fashion jenggot laki-laki yang satu ini sekarang ini lagi berkembang dan sangat diminati , jenggot dimaksudkan sebagai tanda ke-macho-an kaum pria. Ini alasan yang sangat masuk akal. Laki-laki memang memiliki hormon rambut-rambut dan bulu di wajah facial hair yang sejak dari jaman dahulu telah digunakan sebagai sarana menunjukkan ketampanan, kedewasaan, dan pesona laki-laki di mata kaum Hawa. Jenggot bukan hanya sekedar perintah dari hukum agama, namun lebih dari itu, memelihara jenggot bermanfaat untuk kesehatan. memelihara jenggot terbukti ilmiah dapat menyehatkan. Lebih-lebih dalam hal mencukur jenggot ini, ada unsur-unsur menentang fitrah dan menyerupai perempuan. Sebab jenggot adalah lambang kesempurnaan laki laki dan tanda yang membedakannya dengan perempuan.
PERSPEKTIF ISLAM TENTANG TEORI KONEKSIONISME DALAM PEMBELAJARAN
Authors: Saifudin Saifudin
Published: August 2022

Faktor penting keberhasilan belajar seseorang adalah metode belajarnya. Untuk kepentingan tersebut para ahli dan ilmuan mengembangkan pelbagai konsep, bentuk dan model metode belajar. Dalam pelbagai literatur disebutkan bahwa metode-metode belajar yang dikembangkan adalah sebagai berikut, yaitu: Psikologi Klasik, Psikologi Daya, Mental State, Behaviorisme, Koneksionisme, Psikologi Gelstalt, dan Psikologi Filed Theory. Dari tujuh metode tersebut, teori atau metode belajar koneksionisme banyak dikaji dan diaplikasikan oleh orang tua, guru/dosen sebagai pendidik anak-anak didiknya serta masyarakat pada umumnya. Secara empiris, konsep belajar koneksionisme banyak dipraktekkan pada semua tingkat pendidikan, baik pada level pendidikan dasar, menengah, maupun pendidikan tinggi.  Konsep atau teori belajar koneksionisme dikembangkan oleh Edward Lee Thorndike (1874-1949). Sebagai pakar psikologi Pendidikan, Thonndike dalam mengembangkan teorinya melakukan pelbagai macam ekspirimen yang mengkombinasikan kajian psikologi dan biologi. Oleh karena itu secara epistemologis, teori dan hasil kajiannya sarat dengan metode-metode ilmiah khas Barat. Kendati demikian, teori belajar koneksionisme tersebut telah banyak dipraktekkan di dunia pendidikan, termasuk pendidikan Islam. Agar para orang tua dan guru/dosen tidak terjebak pada koneksionisme an sich, diperlukan kajian kritis atas teori tersebut dalam perspektif Islam. Masalah pokok yang dikaji dalam penelitian adalah apa dan bagaimana konsep/teori koneksionisme dikembangkan dalam pembelajaran dan bagaimana pandangan Islam atas teori tersebut.