bluuebunny/crossref_metadata_2025 huggingface dataset:
Impacto del acceso a los servicios de agua y alcantarillado en anemia en niños menores de 5 años en Perú
Authors: Guzmán-Castillo Wagner , Acosta Sullcahuaman Luis Alberto , Lázaro Pérez Arturo Rodolfo , Gonzales Chavez Christiam Miguel , Moreno Alvarado Herman Paul , Peña Wagner Cynthia Roxana , Leiva Ganoza Kate Bertha , Zevallos Timoteo Marcos Yair , Crisólogo Rodriguez Mirton Enrique , Quispe Tito Adolfo , Castillo Villanueva Wilmer
Published: November 2022

La anemia es un problema multidimensional que se agudiza en edades tempranas. Cuando las tasas de prevalencia de anemia superan el 40 %, la OMS lo reconoce como un grave problema de salud pública. En Perú, infantes entre edades de 6 y 36 meses presentan anemia en el 43,5 % del ámbito urbano y el 51,1 % del ámbito rural. El objetivo del estudio fue determinar el impacto del acceso de agua y alcantarillado en anemia en infantes menores de 5 años, para ello, empleamos el Propensity Score Matching como técnica de evaluación de impacto y a través del uso de data de la Endes 2019. Los resultados muestran que, en general, contar con acceso a agua y alcantarillado contribuye a disminuir la presencia de esta enfermedad. Concluimos que en general, contar con servicios de agua y alcantarillado incide en disminuir la anemia en 14,6 % en hogares con infantes menores de 5 años, particularmente, contar con servicio solo de agua, contribuye en una disminución de 12,4 % y solo con servicio de alcantarillado la disminución de anemia en este grupo es de 7,6 %. Al comparar el impacto del acceso de estos dos servicios en anemia según ámbitos urbano y rural, este resulta mayor en el ámbito urbano y cuando se accede solo al servicio de agua, lo cual estaría relacionado con la mayor incidencia de acciones de cloración.
Pharmacokinetic/Pharmacodynamic Study of Salt-Processed Product of Cuscutae
Semen with Hepatoprotective Effects
Authors: Zhang Ying , Xu Shuya , Liu Mengnan , Xu Xinfang , Han Ting , Jia Zhe , Li Xiangri , Lin Ruichao
Published: November 2022

Background:

Salt-processed product of cuscutae semen (SCS), which is documented in Chinese pharmacopoeia
(2020 edition), is one of the processed products of cuscustae semen. SCS possesses hepatoprotective effects.
However, Pharmacokinetic/Pharmacodynamic (PK-PD) study of SCS with intervening acute liver injury (ALI) has
not been reported yet. Effective constituents are still not well addressed.

Objective:

This study was performed to study PK-PD properties with the purpose of linking SCS hepatoprotective
effects to key therapeutic outlines to guide therapeutic use in clinical settings.

Methods:

Rats were orally administered SCS after the acute liver injury model was established. Plasma biochemical
analysis, antioxidative analysis, and liver histopathology were measured to evaluate the hepatoprotective effects of
SCS. Blood samples were collected at different time points (0 h, 0.083 h, 0.25 h, 0.5 h, 1 h, 1.5 h, 2 h, 3 h, 4 h, 8 h,
12 h, 24 h) for PK/PD study after SCS administration. Contents of chlorogenic acid, hyperoside and astragalin were
estimated by UHPLC-ESI-MS. The relationship between concentrations of chlorogenic acid, hyperoside, and
astragalin and hepatoprotective effects was assessed by PK-PD modeling.

Results:

The results showed that SCS ameliorated liver repair and decreased the serum levels of alanine aminotransferase
(ALT), aspartate transaminase (AST) markedly. Hepatic oxidative stress was inhibited by SCS, as evidenced
by a decrease in malondialdehyde (MDA) and an increase in glutathione (GSH) and superoxide dismutase (SOD) in
the liver. PK-PD correlation analysis indicated that concentrations of chlorogenic acid, hyperoside, and astragalin
were negatively correlated with level of AST and ALT.

Conclusion:

The encouraging finding indicates that SCS has beneficial effects on CCl4-induced liver damage. Chlorogenic
acid, hyperoside, and astragalin are three effective constituents to exert hepatoprotective effects while astragalin
may have maximum pharmacological activity. PK-PD study reveals the positive relationship between drug concentration
and action intensity of SCS against liver injury. This research provides a robust foundation for future studies.
Antidepressant-like Properties of Melatonin and Atorvastatin Combination
following the Restraint Stress in Mice: A Study of Oxidative Stress
Factors
Authors: Nikoui Vahid , Hosseinzadeh Azam , Khotab Solmaz Javadi , Mousavi Seyyedeh Zahra , Abolmaali Meysam , Mehrzadi Saeed
Published: November 2022

Background:

Antidepressant properties of melatonin and atorvastatin have been reported
by clinical and experimental studies. Since both melatonin and atorvastatin possess antioxidant
properties and considering the involvement of oxidative stress factors in depression, the aim of the
present investigation was to study the possible role of oxidative stress factors in the antidepressant-
like effect of melatonin and atorvastatin combination in mice forced swimming test.

Methods:

Following the induction of restraint stress, mice were randomly divided into eight
groups including the non-stressed and stressed vehicle-treated groups, melatonin- and atorvastatintreated
groups, a combination of melatonin and atorvastatin-treated group, and fluoxetineadministrated
group. The open field test (OFT) and forced swimming test (FST) were carried out,
and the hippocampus and prefrontal cortex were removed for the measurement of oxidative stress
factors.

Results:

Induction of restraint stress increased the immobility time in FST, and melatonin (10
mg/kg) significantly reduced it. Atorvastatin at both doses of 1 and 10 mg/kg could not alter the
immobility time, significantly. Co-administration of melatonin and atorvastatin (10 mg/kg) exerted
a significant antidepressant-like response and decreased the immobility time compared with melatonin
or atorvastatin (10 mg/kg), alone. Induction of restraint stress elevated the malondialdehyde
(MDA) levels in mice's hippocampus, while pretreatment of animals with atorvastatin (10 mg/kg)
could reverse it. The co-administration of melatonin and atorvastatin (10 mg/kg) increased the cortical
superoxide dismutase (SOD) activity compared with atorvastatin alone, but could not alter the
catalase (CAT) activity.

Conclusion:

It is concluded that atorvastatin might augment the antidepressant-like properties of
melatonin in FST.
Investigation of the Impact of Tropical Red Clay Soils' Mineralogical Composition on their Physical and Mechanical Properties– a Case Study Ruaka – Kenya
Authors: Hassan Samar Ali , Shitote Stanley Muse , Thuo Joseph Ng'ang'a
Published: November 2022

Introduction:

Residual soils covering large areas of the earth have been chiefly discovered in the last 30 years in most volcanic tropical and subtropical countries. Understanding their behaviour is essential for various infrastructure developments.

Methods:

The physical and mechanical properties of the soils are affected by their mineralogical composition. There is a need to determine the mineralogical composition of the soils and investigate the impact on properties. This paper presents the results of a laboratory study conducted on red clay soil from Ruaka, a suburb in Kenya, to investigate the effect of mineral and chemical composition on the soil’s physical and mechanical properties. Disturbed and undisturbed samples were subjected to different tests such as Atterberg limits, soil classification, consolidation test, X-ray fluorescence, X-ray diffraction and petrology test based on the British Standard soil classification system (1377-1994). The soils were classified as clay with high plasticity, and high clay content varied between 59-79% resulting in mechanical instability of the soil in this site.

Results:

The mineral and chemical analysis indicated the formation of unique minerals like Halloysite, Quartz, Kaolinite, and Mica, which influenced the geotechnical properties of clay. The index properties of clay recorded high values; the moisture content and plastic limit varied between 37- 46% with a slight increase as depth increased; the liquid limit varied between 63-68% with increased depth.

Conclusion:

The average value of maximum dry density was reported as around 1247 kg/m3 with high optimum moisture content, reaching 35.5%. Besides that, the soil had a high void ratio of 1.145 to 1.63, which increased the permeability of the clay to 1.223E-5 cm/s. The properties of red clay soils in more than ten tropical regions in Kenya compared with the soil under study are also presented in this paper.
An investigation of the lexico-grammatical profile of English legal- lay language
Authors: Busso Lucia
Published: November 2022

The article presents a study on the lexico-grammar of the genre ofEnglish legal-lay language (Tiersma 1999), using the English subcorpus of theCorIELLS corpus (Busso forthcoming). The study explores four grammaticalconstructions (in Goldberg 2006’s Construction Grammar sense): nominalisationsheading prepositional phrase attachments, modal verb constructions, participialreduced relative constructions, and passive constructions. Specifically, we usecollostructional analysis (Stefanowitsch 2013), followed by a vocabulary analysisusing English core vocabulary as a reference (Brezina and Gablasova 2015), anda comparative frequency analysis with corpora of legal language and general-domain written prose. Results of this first part of the study foreground how legal-lay language is quantitatively different from both neighbouring genres, suggestingthat it might be considered a “blended” genre. We further explore the data in termsof accessibility for speakers, using readability metrics and a survey on Englishparticipants. Both methods show that legal-lay language is at an intermediatelevel of complexity between legal jargon and general-domain prose; however, wefurther note that readability metrics generally underestimate speakers’ ability tocomprehend legal-lay language.
Variación genética de Balmea stormiae (Rubiaceae) en el centro-occidente de México
Authors: Mejía-Jiménez Dulce Karina , Montero Castro Juan Carlos , González-Rodríguez Antonio , Lara-Cabrera Sabina Irene , Ruiz-Sánchez Eduardo , Mendoza-Cuenca Luis Felipe
Published: November 2022

Antecedentes y Objetivos: Los individuos de Balmea stormiae (Rubiaceae) son árboles o arbustos hemiepífitos que habitan malpaíses con bosques de pino-encino en poblaciones disyuntas en Centroamérica y México. La especie se considera en peligro de extinción y particularmente se ha documentado que las poblaciones de Michoacán han estado expuestas a fuertes presiones antropogénicas. Por tal motivo, en este estudio se estimó la diversidad genética en cuatro poblaciones de Michoacán, contrastando esta información con la obtenida en una población de Jalisco, ambas regiones ubicadas en el centro-occidente de México.Métodos: Las muestras vegetales fueron recolectadas en cinco poblaciones de la región occidente del Cinturón Volcánico Transmexicano. Para evaluar la diversidad genética, se utilizó el intrón rps16 del ADN de cloroplasto, el espaciador transcrito externo (ETS) del ADN ribosomal nuclear y marcadores dominantes ISSR de ADN nuclear (Inter Secuencias Simples Repetidas por sus siglas en inglés).Resultados clave: Los marcadores moleculares revelaron alta diferenciación genética entre las poblaciones de Jalisco y Michoacán, la cual se atribuye a la baja conectividad entre estas. Posiblemente se deba a la baja capacidad de dispersión a larga distancia de las semillas y el polen. Se detectó flujo genético moderado y expansión demográfica reciente en las poblaciones de Michoacán. Los niveles de variación genética en las poblaciones de Michoacán concuerdan con la edad de los flujos de lava, siendo Arocutín y Zacapu las poblaciones más diversas sobre los flujos de lava más antiguos.Conclusiones: Los resultados podrían explicarse por el origen relativamente reciente, producto de la actividad volcánica del Holoceno, de los ambientes en los que habita esta especie, sumado a la perturbación recurrente relacionada con grandes asentamientos prehispánicos de Michoacán.
Extrusión húmeda y tratamiento químico del pasto maralfalfa (Pennisetum sp)
Authors: Jaimes Cruz Ligia Johana Johana , Correa-Cardona Héctor Jairo , Giraldo-Mejía Ángel
Published: November 2022

Objectives. Test the effect of wet extrusion and the application of two alkaline compounds on the in vitro digestibility of dry matter (IVDDM) and neutral detergent fiber (IVDNDF) of maralfalfa grass. Methods. 48 samples of 51 days of regrowth were chopped and assigned to eight treatments: raw, chopped, and dehydrated grass (CTRL); raw, chopped, and extruded grass (EXTR); EXTR treated with 0.45, 0.90, and 1.35% of lime (Ca(OH)2) or urea for 21 days in micro-silos under aerobic conditions (EXTR0.45Ca, EXTR0.90Ca, EXTR1.35Ca, EXTR0.45U, EXTR0.90U, and EXTR1.35U, respectively). The content of dry matter (DM), nitrogen (N), calcium (Ca), neutral detergent fiber (NDF), acid detergent lignin (ADL) and the in vitro digestibility of dry matter (IVDDM) and NDF (IVDNDF) were determined for each sample. Results. The EXTR presented lower N content, higher NDF content, and higher IVDNDF than the CTRL. On the other hand, the EXTR1.35Ca treatment showed the highest Ca concentration and the highest IVDDM and IVDNDF, while the EXTR0.90U treatment presented the highest N concentration and an IVDNDF statistically similar to that of the EXTR1.35Ca. Conclusions. The wet extrusion of maralfalfa grass alone increases IVDNDF; however, IVDDM and IVDNDF are maximized when treated with 1.35% of Ca(OH)2.
Cytohistopathological Correlation of 884 Cervical Pap Smears as Bethesda System 2014: A Hospital-Based Study
Authors: Khairwa Dr Anju
Published: November 2022

Cervical carcinoma is most common in Indian women of which Rural women are predominantly affected. The most common etiological factor is human papillomavirus (HPV ). The present study aims to assess the diagnostic accuracy, sensitivity, specificity, and different patterns of cervical Pap smears by comparing histological findings. The index study is a retrospective cross-sectional analytical study. The data was collected at the pathology department from May 2017 to December 2019 according to hospital ethical protocol. Cervical Pap smears received by the pathology department underwent Pap staining. A total of 884 Pap smears were satisfactory and included in the study. The age of enrolled women was 46.4 ± 9.7 years. 800 cervical Pap smears were reported as negative for intraepithelial lesion (NILM), and 84 Pap smears were reported as abnormal. Abnormal pap smears included 64 (7.1%) atypical squamous cell-undetermined significance (ASC-US), 9 (1.01%) low-grade squamous intraepithelial (LSIL), 5 (0.56%) high-grade squamous intraepithelial lesion cannot be ruled out (ASC-H), 3 cases (0.33%) of high grade squamous intraepithelial lesion (HSIL), 2 cases (0.22%) of atypical glandular cell-not specific otherwise (AGC-NOS) and 1 case (0.11%) of squamous cell carcinoma. The cytohistological correlation was found in 56 patients, including 41.07% with chronic cervicitis, 26.75% with chronic cervicitis with squamous metaplasia, 5.35% with cervical polyps, 3.57% with CIN-1, 14.28% with carcinoma in situ, 7.14% with squamous cell carcinoma (keratinizing), 1.78% with squamous cell carcinoma (non-keratinizing) patients. Cytohistological correlation of 56 cases revealed sensitivity (83.33%), specificity (94.73%), PPV (88.23%), NPV (92.3%) and accuracy (91.07%). The cervical Pap test is cost-effective, almost as sensitive, and accurate as histology in screening for cervical lesions.
Investigación educativa
Authors: Acosta Torres Laura Susana , de la Fuente Hernández Javier , Sifuentes Valenzuela María Cristina , Martis Florez José Ramiro
Published: November 2022

En las páginas de este libro se recogen dos experiencias y seis trabajos de investigación educativa, desarrollados individualmente o en equipo, en condiciones y campos de conocimiento diferentes, pero todos tienen en común el contexto de una investigación educativa no experimental, emergente, de carácter interpretativa o de investigación-acción, y que en función de su finalidad se aplicaron metodologías para asegurar la precisión de la información, la verificación y explicación de los resultados, el empirismo de los datos o fuentes de información y el razonamiento para presentar las conclusiones.
C,T1,T2: A COMPLEMENTARY METHOD TO DETECT MULTIPLE POPULATIONS WITH THE WASHINGTON FILTER SYSTEM
Authors: Frelijj H.
Published: November 2022

The Planetary Society's LightSail-2 mission successfully validated the orbital maneuvering capability of a solar radiation pressure (SRP) propelled spacecraft. This paper presents a study on two alternative attitude strategies for the orientation of a solar sail. The goal is to increase the effect of the SRP acceleration over the spacecraft's orbital trajectory, with the intention of maintaining or even gaining altitude over time. Furthermore, one of these strategies was employed while varying a few of the mission's parameters to determine if it would be viable to maintain the spacecraft's average altitude. Results show that it is possible to increase the average altitude of the spacecraft over time while still reducing the number of maneuvers necessary to change the spacecraft's attitude. With that result in hand, it is also possible to change some of the mission parameters without compromising the solar sailing performance.
Graph Theory in Social Media Related to Whatsapp
Authors: K B Vidhyadharani , M Ramya
Published: November 2022

Abstracts: Graphs are extensively used to model social structures based on different kinds of relationships between people or groups of people. WhatsApp media can conveniently be modelled using graphs, the connection between individuals in WhatsApp media can be described using graphs ranging from two individuals connected and communicating to different WhatsApp groups, this can be comfortably explained by graphs. The idea of directed graphs, undirected graphs and adjacent matrix as it’s related to WhatsApp groups has been presented.
Legal Assistance of the Justice Seeking Community through the Legal Aid Postal Service at the Pasarwajo Religious Court
Authors: Salam Safrin , Suhartono Rizki Mustika , Karim La Ode Muhammad , Anisa Siti Nur , Mayanti Sri
Published: November 2022

Keberadaan Lembaga Bantuan Hukum dalam mewujudkan keadilan yang berpihak pada masyarakat keadilan sangat penting di Negara Indonesia. Salah satu perwujudan itu diwujudkan dalam bentul Pemberian Layanan bantuan hukum yakni Pos Bantuan Hukum di Pengadilan Agama Pasarwajo. Kegiatan ini merupakan bentuk pengabdian kepada masyarakat antara dosen fakultas hukum, Yayasan Lembaga Bantuan Hukum Amanah Peduli Kemanusiaan yang bermitra dengan Pengadilan Agama Pasarwajo dalam pemberian bantuan hukum kepda masyarakat miskin. Pada dasarnya, Posbakum Pengadilan Agama Pasarwajo telah menerapkan dan melaksanakan ketentuan yang ada dalam Perma Nomor 1 Tahun 2014 jo. SOP Pelayanan Pos Bantuan Hukum (POSBAKUM) Pengadilan Agama Pasarwajo No : SOP/AS/02 Tanggal 2 sedangkan peran Posbakum Pengadilan Agama Pasarwajo ada 4 yakni a) Memberikan bantuan hukum secara prodeo menurut UU 16 Tahun 2016 dan Perma No. 1 Tahun 2014; b) Memberikan akses keadilan bagi masyarakat yang kurang mampu terhadap pelayanan pengadilan; c) Melaksanakan asas peradilan yang cepat, murah dan biaya ringan; d) Mewujudkan peradilan yang agung sebagai mitra dari pengadilan agama pasarwajo.
Legal Assistance of the Justice Seeking Community through the Legal Aid Postal Service at the Pasarwajo Religious Court
The existence of legal aid institutions in realizing justice in favor of the justice community is very important in the State of Indonesia. One of the manifestations is manifested in the form of providing legal aid services, namely the Legal Aid Post at the Pasarwajo Religious Court. This activity is a form of community service between law faculty lecturers and The Amanah Peduli Humanitarian Legal Aid Foundation (YLBH ALIM), in partnership with the Pasarwajo Religious Court, in providing legal assistance to the poor. Basically, the Pasarwajo Religious Court Posbakum has implemented and implemented the provisions contained in Perma Number 1 of 2014 jo. SOP for Legal Aid Postal Services (POSBAKUM) of the Pasarwajo Religious Court No. SOP/AS/02 dated two while the roles of Posbakum for the Pasarwajo Religious Court are 4, namely a) Providing legal assistance on a free basis according to Law 16 of 2016 and Perma No. 1 of 2014; b) Providing access to justice for underprivileged communities to court services; c) Implementing the principle of fast, low-cost and low-cost justice; d) Realizing a great judiciary as a partner of the Pasarwajo.
Zona perifolicular dentária no gato
Authors: Louro Leopoldo Marques
Published: November 2022

Estuda-se: osteogênese, mesênquima e vascularização ao redor do folículo de molar de gatos com 8 a 10 horas, 2, 4 e 10 dias. Através de diversas medições, procura-se estabelecer relação entre folículo e alvéolo.
Osteoma do seio maxilar: apresentação de um caso
Authors: Kilian Egon A.
Published: November 2022

Revisão geral sobre osteomas do crânio, considerando sua patogenia e classificação. Um caso de osteoma esponjoso, situado no seio maxilar direito, que foi removido por acesso vestibular, foi apresentado.
Currículo ideal de odontologia
Authors: Schifino Leonardo
Published: November 2022

O autor, neste artigo, trata da organização de um currículo ideal para o Ensino Odontológico no Brasil, levando em conta seu panorama real e atual, baseando-se nas condições da Faculdade de Odontologia de Porto Alegre, da Universidade do Rio Grande do Sul. Faz considerações sobre uma série de itens que poderiam melhorar o ensino como número de horas-aluno, provas parciais teóricas e arguições, provas de segunda época, trabalhos práticos, adestramento manual, trabalhos em manequim e pacientes, trabalhos de ambulatório, inter-relação de cadeiras, etc. Apresenta um currículo que considera ideal para o Ensino Odontológico brasileiro e aponta as medidas que poderiam levar a sua execução.
Dispositivo prático para levantamento radiográfico da maxila
Authors: Vale José D. Freitas
Published: November 2022

O autor descreve, detalhadamente e com ilustrações, a confecção e emprego de um dispositivo prático de resina acrílica para suporte de películas radiográficas intraorais. Na técnica radiográfica é descrito o levantamento radiográfico completo da maxila com, no máximo, 5 (cinco) películas do tipo «standard».
Alterações nas bases de dentaduras de resina
Authors: Martins Eleutério A. , Filho Solon Galvão
Published: November 2022

É apresentado um levantamento e feita uma análise da literatura relativa a desarmonia oclusal decorrente das alterações ocorridas nas bases dimensionais de dentaduras de resina acrílica ocorridas durante e imediatamente após a conversão. Da análise pode-se concluir que: 1. Todas as fases da conversão são importantes. 2. Material de inclusão, meio isolante, espessura das bases, manipulação da resina, pressão de moldagem, ciclo de polimerização sao fatores que devem ser analisados em conjunto quando da interpretação de dados de qualquer pesquisa. 3. A fricção da resina de encontro às paredes do molde somada à espessura das bases parecem ter influência capital nos problemas de indução e libertação de esforços.
Estado y políticas públicas de educación en Colombia
Authors: Ángel Osorio Julialba , Nieto Gómez Libia Esperanza , Giraldo Díaz Reinaldo , Cabrera Otálora Martha Isabel
Published: November 2022

En este libro se muestran resultados de investigaciones que se han ido madurando al interior del grupo, perspectivas que han sido ensayadas, presentadas a la comunidad académica y a la sociedad a través de artículos de investigación en revistas científicas, los cuales han recibido retroalimentación de lectores, investigadores y académicos en Colombia y en el mundo. Con esta publicación se da respuesta a inquietudes planteadas en las investigaciones, se hace énfasis en algunos conceptos, se amplían horizontes de análisis, referentes teóricos, fuentes bibliográficas para reunirlos en una única publicación. Igualmente, en el libro se muestran estudios más recientes que desarrolla el Grupo de Investigación Tecnogénesis.
Estado del arte: Tendencias de la investigación sociológica en Colombia 1997-2013
Authors: Wilches M. Luis Eduardo , Meneses Tania , Martínez Carlos , Rojas Sonia , Quitián David , Ríos Jaime
Published: November 2022

Este informe presenta los resultados finales de la investigación Estado del Arte: tendencias de la investigación sociológica en Colombia, entre 1997 y 2013. Parte de dos grandes tensiones articuladoras y propositivas: la brecha del conocimiento, como eje global de legitimación del conocimiento, el papel de la disciplina frente a este fenómeno hegemónico y la necesidad de aproximar al qué hacer de la disciplina con enfoque Glocal, para alcanzar una lectura de país desde y con los territorios, es decir con la Colombia profunda. La investigación cualitativa, de corte documental y con enfoque comprensivo desde la lógica de la teoría fundamentada posibilitó, no sólo el ejercicio de reconocer los temas de interés que los grupos de investigación de las instituciones de formación superior en Sociología en nuestro país, sino que además realza la necesidad y genera propuestas de articulación del programa con la Red Colombiana de Facultades y Departamentos de Sociología –RECFADES, para apuntar al fortalecimiento de la disciplina en el país y en el contexto latinoamericano.
Factores de riesgo Psicolosociales que inciden en el proyecto de vida de estudiantes universitarios de modalidad a distancia
Authors: Vargas Hurtado Gloria Isabel , Sánchez Ramírez Liliana , Garibello Piñeros María Camila
Published: November 2022

El estudio Factores de riesgo psicosociales que inciden en el proyecto de vida de estudiantes universitarios de modalidad a Distancia, se desarrolló bajo el enfoque mixto de investigación y diseño de tipo descriptivo. Se aplicó la escala (E-FRPED), factores de riesgo psicosociales, a las 8 zonas de la Universidad Nacional Abierta y a Distancia con 2.363 respuestas, identificando las características principales de factores de riesgo, acorde con cada dimensión: psicológica (cognición, emocióny personalidad); socioambiental (estilo de vida, relaciones interpersonales, proyecto de vida y transformación personal) y pedagógica (modalidad a distancia, pedagogía y gestión del estudio independiente). Los resultados destacan la identificación de Factores Psicosociales Protectores donde los estudiantes reconocen fortalezas que ofrece la universidad en su formación profesional.
Extracerebral anaplastic meningioma
Authors: Carillio Guido , Lavecchia Anna Maria , Misuraca Demetrio
Published: November 2022

Anaplastic meningioma rarely involves organs outside the brain. In our
case a patient with cerebral meningioma developed lung metastases after
19 years from the initial appearance. This unusual tumor presentation
could make complex the diagnosis.
Late diagnosis of X-linked hyper-IgM syndrome presenting as community-acquired pseudomonas aeruginosa pneumonia-related septic shock
Authors: Yang Lin , Chen Lina , Xie Liang , Xiong Ying , Liu Hanmin
Published: November 2022

Pseudomonas aeruginosa (P. aeruginosa) is a gram-negative aerobic
bacterium, which is rarely seen in community-acquired infection.
Attention should be paid to its high mortality and invasive progress.
X-linked hyper-IgM syndrome (XHIGM; HIGM1; OMIM:308230) is one type of
primary immunodeficiency disease (PIDs), characterized by markedly
decreased serum IgG, IgA, and IgE levels and normal or elevated serum
IgM levels. We report a patient who developed a particularly severe
community-acquired P. aeruginosa pneumonia-related septic shock, and a
delayed diagnosis of X-linked hyper IgM syndrome was made by genome
sequencing. Fatal community-acquired P. aeruginosa infections in
children, including previously healthy children, should be considered to
search for underlying PIDs by exome/genome sequencing.
Sentinel node performance by laparotomy in a large myomatous uterus with early-stage endometrial cancer: lessons to be learned
Authors: MARGIOULA-SIARKOU CHRYSOULA , PETOUSIS STAMATIOS , Alberis Aristarchos , DINAS KONSTANTINOS
Published: November 2022

Even in cases of large myomatous uterus where laparoscopical resection
is not feasible, it is still possible to perform the method of sentinel
node with open surgical technique. We present the clinical image of a
large myomatous uterus with endometrial cancer where sentinel node was
performed succesffuly by laparotomy.
Use of thyroid hormones in hypothyroid and euthyroid patients: A THESIS questionnaire survey of Serbian physicians
Authors: Nedeljkovic-Beleslin Biljana , Attanasio Roberto , Hegedüs Laszlo , Nagy Endre , Negro Roberto , Papini Enrico , Perros Petros , Ciric Jasmina , Zarkovic Milos
Published: November 2022

Introduction/Objective. Hypothyroidism is a common disease and treatment with levothyroxine (LT4) is effective. However, variations in management are frequent. The aim of this study was to identify practices and attitudes of Serbian physicians relating to the treatment of hypothyroidism. Methods. An anonymized questionnaire was distributed electronically to members of the Serbian Thyroid Society, Serbian Association of Endocrine Surgeons, and Section for Endocrinology of the Serbian Medical Society. Results. Out of 170 invitations, 99 responses were received. LT4 was the first choice for the treatment of hypothyroidism in 90% of patients. After starting LT4 replacement therapy most respondents would recheck thyroid-stimulating hormone (TSH) in 4?6 weeks (n = 51, 62%) and in eight weeks (n = 29, 35%). In total, 61% of respondents (n = 60) indicated that they would consider treating euthyroid patients with LT4, the commonest indication being female infertility with high levels of thyroid antibodies (54%, n = 50). More than half respondents (58%, n = 45) would recommend combined LT4 + LT3 therapy for patients on LT4 with normal serum TSH who still complain of symptoms of hypothyroidism. 53% (n = 41/77), reported that the frequency of patients with normal serum TSH who still complain of hypothyroid symptoms is less than 5%. Conclusion. LT4 was the first choice of therapy for the treatment of hypothyroid patients, whereas LT3 + LT4 combination treatment is considered in patients with persistent symptoms of hypothyroidism despite normalization of TSH. The most common indication for thyroid hormone treatment in euthyroid patients was female infertility with high levels of thyroid antibodies. Alternative LT4 formulations like liquid solution or soft-gel capsules ?formulations presently not available in Serbia, were largely reserved for specific conditions (interfering drugs, malabsorption, inability to take LT4 in the fasting state, unexplained poor biochemical control of hypothyroidism).
Auditor Style and Common Disclosure Issues: Evidence from SEC Comment Letters
Authors: Baugh Matthew D. , Schmardebeck Roy
Published: November 2022

Policies and procedures that centralize decision making within an audit firm create auditor style effects. Prior research suggests this style increases financial-statement comparability, implicitly making financial statements more useful. However, a potential hazard of auditor style is the propagation of decision errors. We examine the association between auditor style and common disclosure issues among audit clients. We measure auditor style as the presence of a common auditor and use comments given in the Securities and Exchange Commission’s (SEC’s) filing-review process to measure the occurrence of common disclosure issues. We find that auditor style is associated with common disclosure issues among Big 4 clientele. We also find that clients with the same auditor converge in issues as tenure increases and some evidence that clients assume the issues of a subsequent auditor. These results provide the first evidence that auditor style has potential costs in the form of common disclosure issues.

Data Availability: All data are publicly available.

JEL Classifications: M41; M42.
As repercussões da intervenção de D. Martinho da Costa Lopes na Comissão de Direitos Humanos das Nações Unidas
Authors: Silva Fernandes Moisés
Published: November 2022

After leaving Dili on 17 May 1983, the former Apostolic Administrator of Dili, Monsignor D. Martinho da Costa Lopes, went abroad to try to raise awareness of the tragic situation in which Timor-Leste found itself, after it became annexed by Indonesia on 7 December 1975. Almost eight months later, he went to the United Nations’ Human Rights Commission in Geneva, with the support of Pax Christi International. Monsignor D. Martinho da Costa Lopes was a pioneer of peace through self-determination and independence for Timor-Leste, which was only achieved in 1999.
Metabolomics and Its Role in Inflammatory Bowel Disease: What Do We Know?
Authors: Tsonev Nikolay , Zvezdov Dimitar , Gashkova D. , Andreeva D. , Stefanova M.
Published: November 2022

Inflammatory bowel diseases comprise of ulcerative colitis and Crohn's disease, both of which have increasing incidence. Despite not having completely understood pathogenesis, genetic factors, environmental factors and microbiota are thought to play a role in a predisposed individual. Common symptoms include abdominal pain, diarrhea, fever, weight loss and rectal bleeding. Diagnosis is made by clinical, laboratory, endoscopic, radiologic and histologic examinations. Nevertheless, about 15% of patients do not have a definitive diagnosis. Metabolomics measures metabolites in a biological sample (feces, serum, urine, tissue and air) thereby having the potential to clarify disease pathogenesis and find new biomarkers, which will then aid in diagnosis, guide therapy and give prognosis.
Challenges and Opportunities of Online Assessment Implementation During Covid-19 Pandemic in Indonesia Based on Recent Studies
Authors: Diarsini Made Sri , Artini Luh Putu , Padmadewi Ni Nyoman , Ratminingsih Ni Made , Utami I Gusti Ayu Lokita Purnamika , Marsakawati Ni Putu Era
Published: November 2022

Online learning has become a new trend in Indonesian educational practices due to the Covid-19 pandemic. Since the teaching and learning process changes from face-to-face to online, conducting online assessments has become a requirement. The shift brings some challenges and opportunities. This study attempts to describe the challenges and opportunities of implementing online assessment during the Covid-19 pandemic in Indonesia. A library research method was implied by analyzing related research articles conducted between 2020-2022. The research procedures adapt George’s (2008) library research model. The findings reveal three challenges related to internet connectivity and the consequence of indirect interactions between the students and instructors. The first challenge is that online assessment is costly. Both teachers and students are required to pay the costs of internet access, own a digital device, and possess digital literacy. The second challenge is the possible problem of cheating and plagiarism. The next challenge is difficulty to follow students’ progress, interact effectively with them, and handle-less motivated and discouraged students. However, there are some opportunities as far as online assessment is concerned. There is more flexibility with time and space, direct and immediate feedback to students, strategies to deal with students’ anxiety, encouraging autonomous learning, increasing knowledge and experiences in online language assessment, and time management skill.
Description of Grade VII Students'Concept Understanding on Set Topic
Authors: Rezki Miftahul , Rifandi Ronal , Tasman Fridgo , Yokri Veggi , Yerizon
Published: November 2022

This research has the aims to explain about the understanding of students mathematical concepts on set topic. This research is a descriptive research whose population is 7th grade students with a sample of 94 students. The instrument used in this research is a test question regarding the set material which contains indicators of mathematics conceptual understanding. The result of the test analysis show that as many as of students with exellent concept understanding, of students with good concept category, of students with sufficient category, of students with low concept criteria, and of students with most low concept understanding criteria.
Ježiš - sapienciálne výroky
Authors:   Univerzita Mateja Bela v Banskej Bystrici, Pedagogická fakulta, Katedra teológie a katechetiky PDF, Šoltésová Viktória
Published: November 2022

Cieľom práce je rozpoznanie sapienciálnych výrokov v Ježišovom učení analýzou relevantnej múdroslovnej literatúry, kánonických aj nekánonických zdrojov o živote a učení Ježiša Krista. Práca sa bude snažiť komparatívnou metódou zameranou na žáner múdroslovia v Starom zákone a prípadného múdroslovia v Novom zákone v Ježišových rečiach, odpovedať na otázky, ktoré prirodzene vyvstávajú pri štúdiu daných textov. Metódou biblickej exegézy analyzujeme vybrané Ježišove reči, ktoré môžu mať múdroslovný charakter. Komparatívny rozbor poukazuje na paralely v rôznych textoch príbuzného žánru a spôsob výkladu múdroslovia. Výsledkom výskumu by mala byť zbierka Ježišových múdroslovných výrokov tematicky rozdelených do kategórií.
Possible Integration of the Security System of the Member Countries of the European Union
Authors: Matis Jozef , Nagyová Lenka
Published: November 2022

The processes of globalization and postmodernism are important determinants of the integration of the European Union countries in the field of ensuring security. Ensuring security of the European Union countries requires the creation of an integrated security system of these countries. This study is concerned with the theoretical analysis of an important factor - disponible (available) groups - in ensuring security of the European Union. These groups were defined as professional or volunteer response forces of a military, paramilitary and non-military nature.Two possible ways of integrating national disponible groups into the developing security system of the European Union ensuring its military as well as non-military security were analyzed. The success of integration of the national security systems of the European Union countries into the security system of the European Union depends not only on the elites - national (local) and transnational, but also on the transformation of citizens of national (member) states into citizens of the European Union - European citizens.
Risk Factors for Peri-implant Diseases
Authors: Ser-Od Tungalag
Published: November 2022

No abstract in English
Dietary Intake of Polyunsaturated Fatty Acids Lowers the Risk of Osteoporosis in Older Korean Females
Authors: Lee Kyujo , Kim Kyeong-Rae , Choi Syungkyun , Jang Il-Tae , Kim Hyunwoo
Published: November 2022

Objectives: Osteoporosis is an important issue because it is associated with the risk of fractures. However, there is no study in the Republic of Korea on the relationship between PUFAs and the osteoporosis prevalence in middle-aged Korean women using public data. Methods: We intend to prepare basic data for osteoporosis by analyzing the prevalence of osteoarthritis in 3,294 women aged over 50 based on demographic and nutritional characteristics using the 7th KNHANES data using multiple logistic regression. Results: In unadjusted logistic regression analysis, the group with higher than average daily intake of PUFA had a lower prevalence of osteoporosis than the group with lower PUFA intake. In the final model, after adjustment for demographic variables such as sex and age, the group with high PUFA intake had up to 20% lower prevalence of osteoporosis than the other group. However, the effect size in the adjusted and unadjusted models was increased. Conclusions: A higher consumption of omega-3 and omega-6 fatty acids than the average daily intake in Korean women ages 50 years and older was negatively correlated with osteoporosis prevalence. We infer that adequate intake of PUFAs such as omega-3 and omega-6 fatty acids may help prevent osteoporosis.
Antiviral Efficacy and Safety of Tenofovir Alafenamide Compared to Tenofovir Disoproxil Fumarate in the Treatment of Chronic Hepatitis B
Authors: Narangerel Tuvshinbayar , Ravdan Amaraa , Baljinnyam Gegeebadrakh , Badrakh Burmaajav , Oidov Baatarkhuu
Published: November 2022

Objectives: To provide compare of the efficacy and safety tenofovir alafenamide (TAF) to tenofovir disoproxil fumarate (TDF) in patients with HBeAg-negative and HBeAg-positive chronic hepatitis B. Methods: We performed a randomized, unblinded, non-inferiority study in which patients with compensated cirrhosis (Child-Pugh A and B stage) between 18-70 years old with a positive chronic hepatitis B test were randomized to receive either TAF, TDF, or were switched from TDF to TAF. The primary efficacy endpoint was the proportion of patients with HBV-DNA < 29 IU/ml at week 48. Results: The efficacy endpoint, an HBV-DNA < 29 IU/ ml at weeks 48, was achieved by 251 (79.9 %) of 314 patients receiving TAF, which was not significantly different from the 113 (74.8 %) of 151 patients receiving TDF. After 48 weeks of treatment, patients receiving TAF had significantly smaller bone mineral density reductions than patients receiving TDF. At week 48, the median decrease in eGFR was significantly less in the TAF recipients than the TDF recipients. Conclusion: TAF treatment has the same efficacy as TDF treatment. However, TAF treatment had a better safety profile than TDF. Patients receiving TAF had a significantly smaller median decrease in the eGFR by the Cockcroft-Gault equation than patients receiving TDF.
Establishment of Reference Interval for M2BPGI Glyco-Biomarker in the Serum of Mongolian People
Authors: Enkhbayar Uranbaigali , Khuyagaa Ser-Od , Dambadarjaa Davaalkham , Namdag Bira , Radnaa Otgonbayar
Published: November 2022

Objectives: Establishment of reference interval for M2BPGI glyco-biomarker in the serum of relatively healthy Mongolian people. Methods: Serum analysis for M2BPGI glyco-biomarker, hepatitis virus markers, and AFP analysis were performed using a fully automated chemiluminescence immunoassay analyzer. Non-parametric methods were used for establishment of reference interval according to the guideline of the Clinical Laboratory Standards Institute. Statistical analysis was done by using SPSS ver. 20.0; SPSS Inc., Chicago, IL software. Results: Total of 3384 people were involved in this study. Of the total participants, 40% were overweight and 31.3% were obese. Also, of the population 10.1 percent were positive for HBsAg, 17 percent were positive for Anti-HCV, and 1.1 percent had co infection of both HBV and HCV. A total of the 316 individuals met the inclusion criteria for reference interval establishment and 77 (24.4%) of them were men and 239 (75.6%) were women. The reference interval of M2BPGI glyco-biomarker for men was 0.883 ± 0.311C.O.I and for women was 0.951 ± 0.411C.O.I. Conclusion: It is determined that the reference interval for M2BPGI glyco-biomarker in the serum of relatively healthy Mongolian people was 0.936 ± 0.391C.O.I.
Workplace Stress and Physiological Indices Correlation Study Results
Authors: Dondonkhuu Otgonbaatar , Tserenkhuu Lkhagvasuren , Nyam Naranbaatar , Jurmeddorj Munkhkhand
Published: November 2022

Objective: Numerous studies demonstrated that while performing diverse routines in hospitals, nurses often face overcommitment and low social support. We have aimed in this study to address work-related stress level of nurses working at referral hospitals in Mongolia through determining the stress induced changes in blood pressure as well as alpha-amylase level in saliva. Methods: The study involved a totally of 473 nurses from tertiary referral hospitals of Mongolia. We employed the Work Stress Profile questionnaire of Rice and Likert scale in measuring the questions. Additionally, we measured the α-amylase level in the saliva of nurses. The arterial blood pressure, level of glucose in blood and heart pulse were evaluated by a cross-sectional model. Results: The study was conducted by collecting an age group similar to the age pyramid of nurses working in referral hospitals. The participants illustrated low levels of work stress in 7.6%, medium levels in 27.1%, and high levels of work stress in 65.3%, respectively. When we examine whether the level of stress exposure of nurses differs between the groups by high, medium, and low levels of workplace stress, the analysis of one factor variance confirms the statistical real difference (F = 3.071), (p = 0.028). The study results revealed that long lasting accumulated work stress triggers hypertension. Conclusion: The workplace stress of the nurses depends on many different physiological factors.
Elevated Levels of Anti-oxLDL Antibody in Relation with Acute Myocardial Infarction
Authors: Tserendavaa Sumiya , Choi Jung Rae , Malchinkhuu Munkhzol
Published: November 2022

Objectives: We aimed to determine the serum level of anti-oxLDL antibody at the involving of acute myocardial infarction. Methods: In the case-control study, patients with acute myocardial infarction (coronary stenosis > 85%) as determined by quantities coronary angiography in the case group (n = 26) and healthy people with carotid artery stenosis (< 0.7 mm) have been involved in the control group (n = 50). We determined Anti-oxLDL antibody and oxLDL titers by ELISA. Results: Anti-oxLDL antibody levels for the case group were greater than the control group (p < 0.01). Using binary logistic regression, the anti-oxLDL antibody was significantly associated with acute myocardial infarction (OR = 1.082, p < 0.01). Conclusions: Elevated serum anti-oxLDL antibodies may be a risk factor for developing acute myocardial infarction and concerning the correlation of anti-oxLDL antibodies and acute myocardial infarction
Detection of Cell Death Mechanisms: Methods and Protocols
Authors: Odkhuu Erdenezaya
Published: November 2022

No abstract in English
Factors Influencing Satisfaction among Employees in Maternity Hospitals
Authors: Tseleejav Batbold , Luvsansambuu Tumurbaatar , Tudevdorj Erkhembaatar , Jurmeddorj Munkhkhand , Nyam-Osor Munkhtsetseg , Luvsan Munkh-Erdene
Published: November 2022

Objective: To evaluate the level of job satisfaction among the employees of maternity hospitals and to describe variables related to their job satisfaction. Methods: A cross-sectional study was undertaken that focused on 480 full time staff of three maternity hospitals located in the capital city of Mongolia, Ulaanbaatar. Data was collected between July 2019 and September 2019. We selected 3 hospitals as our sample target in order to assess an organizational management capability index using 9 chapters with 90 criteria that used over 30 local public organizations. The Minnesota Satisfaction Questionnaire was used as a data gathering tool to assess employee’s satisfaction which measures on a five-point Likert scale. Results: Overall, 48.0 % of participants had low levels of satisfaction with their jobs. Factors that were statistically significant to employees’ job satisfaction in the univariate analysis were entered into the logistic regression analysis including employees’ professional title, department work hours, work requirements, and life and work stress. The results of the logistic regression analysis suggested that employees’ job satisfaction was related to their age, working hours, leadership attention, wage and promotion as well as cooperation with colleagues. Conclusion: There is an urgent need for maternal hospitals in Mongolia to establish a more reasonable promotion and management system for employees and pay more attention to less-experienced staff and help them release their work stress.