bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of the Albanian University female students' knowledge, attitudes, and practices on cervical cancer
Authors: Merkuri Lumturi , Kamberi Fatjona , Qorri Erda , Shapo Leidon
Published: May 2023

Introduction: Cervical cancer is highly preventable and if diagnosed and treated early, highly curable. Yet it remains the fourth most common cancer in women worldwide. In Albania, cervical cancer is the second most frequent cancer among women 15 - 44 years. A national cervical cancer screening program has been established, which offers HPV tests as part of routine examinations in primary health care centres.
Aim: To assess knowledge, attitude, and practices (KAP) as well as associated factors regarding cervical cancer, among Albanian University female students, and provide useful information for the development of evidence-based preventive strategies for the future.
Methodology: A cross-sectional KAP study was conducted among Albanian University female students during March to May 2022. A total of 503 female students participated in the study (response rate of 82%). A Google questionnaire based on WHO guidance and similar KAP surveys was used to collect the study data. Descriptive analysis was used to analyze the knowledge, attitude, and practices of Albanian female students regarding cervical cancer.
Results: Overall, most students in the study (71.2%) had little knowledge about cervical cancer. Only a fifth of them (20.7%) knew about HPV as a risk factor for the disease with a smaller proportion (18.9%) recognized HPV vaccine as a preventive method. In terms of risky behaviors: 45.9% of respondents showed a positive attitude towards condom use; with 17.7% of students reporting several sexual partners. Only 6.8% of respondents had ever done an HPV test and a total of 7.5% were HPV vaccinated.
Conclusions: The study showed that respondents had a low level of knowledge and unfavorable attitudes about cervical cancer including risk factors, screening, and preventive procedures. The findings could serve as baseline information for further research in this area and highlight the need for more effective information-education-communication strategies to stimulate and support a shift towards positive behaviors of this target group.
Challenges in Managing AUB-C in Adolescence with Acute Lymphoblastic Leukemia in North Sumatera, Indonesia: A Case Report
Authors: Siregar Muhammad Fidel Ganis , Tambunan R. S.
Published: May 2023

Background : Abnormal Uterine Bleeding is a common problem not only cause health disturbance but also affect the physical, social, emotional status, and quality of life of a women. The most common symptom is abnormally heavy or prolonged uterus bleeding. FIGO introduce 9 categories cause of abnormal uterine bleeding, which are known as “PALM- COEIN”. In general, components in “PALM” are components of structural abnormality, which can be diagnosed by imagingand/or histopathological examination. While “COEIN” includes         non-structural abnormality.
Case Report: A 17 years old female without a history of sexual intercourse came to the gynecology polyclinic of the University Of North Sumatra hospital with a chief complaint of irregular menstruation that had been experienced bythe patient since 5 months ago. The patient claimed to have had menstruation for 10-14 days. 4-5 times changing pads. Gynaecology  examination within normal limits. Blood analysis has been done 3 times and the results came up with asignificant decrease of platelet counts and Haemoglobin levels.
Trans Abdomen Ultrasonography was done and showed no abnormality found. The patient was diagnosed with AUB-C in Acute lymphoblastic leukemia.
Conclusion: Abnormal uterine bleeding (AUB) is a common finding in women during their reproductive years. There are steps on how to diagnose an abnormal uterine bleeding disorder (AUB) based on comprehensive history taking, followed by a physical and additional workup.
Keywords: Abnormal uterine bleeding, acute lymphoblastic leukemia, menstrual bleeding, PALM- COEIN.
The COVID-19 Pandemic Influence on Doctor’s Service Performance Using Workload as a Mediation Variable
Authors: Rahmayanti Fida , Noermijati Noermijati , Armanu Armanu , Rohman Fatchur
Published: May 2023

ABSTRACT
Background:
The Covid-19 pandemic greatly affected doctors' increasing workload, especially in Primary Health Care Facilities. If this is not addressed immediately, it will affect the performance or quality of a doctor's service.
Aim:
This research objective is to identify the role of Primary Healthcare Facility doctors' workload in moderating the impact of the Covid-19 Pandemic on their performance.
Methods:
The explanatory-descriptive research was conducted using a quantitative approach. The research respondents were 103 general practitioners who worked at a Primary Healthcare Facility in Malang City (35.0% male and 65.0% female, the most extensive age range was 26-35 years (74.8%), with a working period of 1-5 years. 57 (55.3%) The research instrument was a questionnaire declared valid and reliable, distributed online, and analyzed using Partial Least Square.
Results:
The findings demonstrated that the Covid-19 pandemic significantly positively affected the performance of Primary Healthcare Facility doctors (β=0.455, t stat=11.390). The pandemic also significantly impacted workload (β=0.283, t stat=4.347). Workload impacted performance significantly and positively (β=0.224, t stat 4.157). Workload mediates the Covid-19 Pandemic influence on doctors' performance (β=0.063, t stat=3.005).
Conclusions:
Doctors at Primary Health Care have not all experienced a decline in performance despite the increased workload due to the Covid-19 Pandemic. It forces doctors to juggle between completing their tasks, fighting against disease, and improving their performance.
 
Keywords: Covid-19 Pandemic, Doctor’s Service Performance, Workload, Primary Health Care
A new record of Squalus montalbani (Chondrichthyes: Squaliformes: Squalidae) from the Nansha (Spratly) Islands, South China Sea
Authors: Zhang Mengyi , Shan Binbin , Liu Yan , Wang Liangming , Yang Changping , Liu Manting , Xie Qijian , Sun Dianrong
Published: May 2023

The Indonesian greeneye spurdog (or a dogfish shark), Squalus montalbani Whitley, 1931, is widely distributed in the warm temperate to tropical waters of Indonesia, Philippines, the island of Taiwan, and Australia. Previous studies suggested that the distribution of dogfish shark species in the South China Sea is composed of two species, Squalus mitsukurii Jordan et Snyder, 1903 and Squalus brevirostris Tanaka, 1917. In March 2020 a dogfish shark specimen was collected from the Nansha (Spratly) Islands, South China Sea. We identified it as S. montalbani based on morphology and mitochondrial DNA barcoding. Our results confirmed the presence of S. montalbani in the South China Sea, leading us to conclude that it represents a new species record of the genus Squalus in the region. Furthermore, our findings demonstrate that the combined approach is highly effective in identifying Squalus species that share similar morphological characteristics.
Defining ecological liabilities and structuring ecosystem accounts to support the transition to sustainable societies
Authors: Kervinio Yann , Surun Clément , Comte Adrien , Levrel Harold
Published: May 2023

Harnessing reliable and relevant information on ecosystems requires focusing and prioritising information acquisition on dimensions of interest. As a boundary object between ecosystem monitoring, research and public decision-making, ecosystem accounting can serve this purpose. We develop an argument in favour of a set of accounts, consistent with the statistical standard part of the System of Environmental-Economic Accounting (SEEA-EA), that explicitly links monetary accounts to ecosystem extent and condition accounts. The ecosystem condition account is structured in three categories reflecting the main values motivating integrated ecosystem management targets and notions of «good ecological status». These categories are: (i) the maintenance of their heritage dimensions, (ii) their capacity to sustainably provide ecosystem services and (iii) the maintenance of their overall functionality. We discuss how such ecosystem accounts and associated monitoring can form the basis both for assessing an ecological debt by using a cost-based approach and for designing an action-orientated information system suitable to support the transition towards sustainable societies.
Primulina jiulianshanensis, a new species of Gesneriaceae from Jiangxi Province, China
Authors: Xu Guo-Liang , Liang Li-Fen , Chen Di-Ya , Jing Zhi-Fang , Zuo Xiao-Hai , Zuo Zheng-Yu , Wen Fang
Published: May 2023

Primulina jiulianshanensis F.Wen & G.L.Xu, a new species of Gesneriaceae from Jiulianshan National Nature Reserve of Jiangxi Province, China, is described and illustrated here. Molecular evidence showed it was sister to P. wenii Jian Li & L.J.Yan, while the morphological observation found clear differences between them, petiole, both sides of leaf blades, adaxial surface of the calyx lobes, corolla inside toward the bottom, bract margins covered glandular-pubescent hairs in P. jiulianshanensis (vs. no glandular-pubescent hairs in P. wenii); lateral bracts 4–9 × ca. 2 mm, the central one 2–5 × 1–1.5 mm, adaxially glabrous but sparsely pubescent at apex (vs. lateral bracts 14–16 × 2.5–3.0 mm, the central one 10–12 × 1.3–1.6 mm, all adaxially pubescent); calyx lobes 8–11 × ca. 2 mm, each side with several brown serrate teeth at apex (vs. 14–15 × ca. 2.5 mm, margin entire); filaments and staminodes sparsely yellow glandular-puberulent (vs. white, glabrous).
Les cycles économiques de la France : une datation de référence
Authors: Aviat Antonin , Bec Frédérique , Diebolt Claude , Doz Catherine , Ferrand Denis , Ferrara Laurent , Heyer Éric , Mignon Valérie , Pionnier Pierre-Alain
Published: May 2023

Cet article propose une datation trimestrielle de référence des périodes de récession et d’expansion de l’économie française depuis 1970, réalisée par le comité de datation des cycles de l’Association française de science économique. La méthodologie repose sur deux piliers : 1) des estimations économétriques pour identifier les périodes candidates et 2) une approche narrative détaillant le contexte économique de l’époque pour finaliser la datation. De 1970 à 2019, quatre périodes de récession économique sont identifiées : les chocs pétroliers de 1974-1975 et 1980, le cycle d’investissement de 1992-1993 et la grande récession de 2008-2009. Pour la récession Covid, le pic est daté au dernier trimestre 2019 et le creux au deuxième trimestre 2020. Classification JEL  : E32, E37, C24, N14.
Les diplômes français se sont-ils dévalorisés ?
Authors: Argan Damiano , Gary-Bobo Robert
Published: May 2023

Nous étudions l’évolution des salaires des jeunes diplômés français entre 1992 et 2017, en nous appuyant sur les enquêtes Génération du Céreq. La dévalorisation des diplômes est définie de manière simple comme la baisse des salaires réels moyens des diplômés d’une même catégorie, et nous observons qu’une telle dévalorisation des diplômes s’est bien produite, de l’ordre de 10 %, pour les diplômes universitaires de master et pour les diplômes des écoles d’ingénieurs, entre 1997 et 2015. Il n’y a en revanche pas de dévalorisation pour les diplômes de niveau inférieur au baccalauréat, et nous rapprochons ce dernier résultat de la hausse du Smic. En mettant les données sous la forme d’un panel nous estimons des équations de salaire en contrôlant pour l’expérience (potentielle et effective) et le niveau de diplôme des individus. Les estimations confirment les résultats et montrent que la dévalorisation observée est due en partie à une baisse des rendements de l’expérience. Avec ces méthodes, on ne sait pas ce qui est dû à des changements inobservables dans la sélection des diplômés, mais il semble vraisemblable que la dévalorisation est principalement le résultat de la hausse substantielle du nombre des diplômés du supérieur dans la période étudiée, et non un effet de la conjoncture ou de l’antisélection. Classification JEL  : I24, I26, J24, J31.
Handicap et discriminations dans l’accès au logement : Un test multicritère sur les malvoyants
Authors: Challe Laetitia , Chareyron Sylvain , L’Horty Yannick , du Parquet Loïc , Petit Pascale
Published: May 2023

Nous mesurons l’effet d’une situation de handicap, la déficience visuelle, sur l’accès au logement dans le parc locatif privé en Ile-de-France à l’aide d’un protocole permettant de comparer cet effet à celui d’une origine maghrébine du candidat. Entre juin et juillet 2020, nous avons répondu à 1 000 annonces immobilières, ce qui correspond à l’envoi de 3 000 messages sollicitant la visite d’un logement. Alors même que nous utilisons un signal faible de handicap, une situation de malvoyance, nous mettons en évidence un impact élevé sur les chances d’être invité à visiter un bien immobilier. Le candidat qui signale ce type de handicap a un taux de réponse positive de 7,4 points de pourcentage inférieur au candidat n’affichant pas de handicap, soit une pénalité d’environ 15 % en termes relatifs. La différence est significativement plus faible, de celle obtenue lorsque le candidat fictif signale une origine maghrébine par la consonance de ses noms et prénoms, qui est de 10,5 points de pourcentage. Codes JEL: C81, C93, J15, R31
Women’s Political Participation and Energy Poverty in Sub-Saharan Africa: Effects and Transmission Channels
Authors: Tadadjeu Dessy , Tadadjeu Sosson , Njangang Henri , Djeunankan Ronald
Published: May 2023

La pauvreté énergétique reste un défi majeur pour la croissance économique durable et inclusive, la bonne gouvernance, la paix et la stabilité dans les pays développés et en particulier dans les régions en développement comme l’Afrique. Outre ce défi énergétique, la participation des femmes à la prise de décision politique reste un autre grand défi pour les pays africains. A ce jour, peu d’études ont examiné les effets de la participation politique des femmes sur la pauvreté énergétique. Par conséquent, l’objectif de cette étude est d’examiner les effets de la participation politique des femmes sur la pauvreté énergétique (mesurée principalement par l’accès à l’électricité) dans un panel de 45 pays d’Afrique subsaharienne sur la période 1997-2018. En outre, cet article examine les canaux de transmission par lesquels la participation politique des femmes affecte la pauvreté énergétique. Les preuves empiriques sont basées sur la technique d’estimation par les effets fixes et la méthode des moments généralisés (GMM), et les résultats suivants sont établis : Premièrement, les femmes parlementaires améliorent l’accès à l’électricité à la fois pour la population totale et pour les populations urbaines et rurales. En d’autres termes, les résultats montrent que les femmes parlementaires réduisent la pauvreté énergétique en Afrique subsaharienne. Ces résultats sont robustes à une série de contrôles de sensibilité. Deuxièmement, nous identifions le contrôle de la corruption et la démocratie comme les principaux canaux de transmission par lesquels les femmes parlementaires promeuvent l’accès à l’électricité. Ces résultats mettent en évidence le rôle important des femmes politiques dans la réalisation des objectifs de développement durable, notamment l’accès à l’électricité en Afrique.
Cannabis Toxicity in Children and Adolescents
Authors: George Princy , Wahl Michael
Published: May 2023

The legalization of recreational and medical cannabis has increased the availability and potency of cannabis products in homes and communities. Although state laws regarding legalization and commercial sale often encompass adult use only, pediatric toxicity from unintentional exposures to cannabis edibles and adolescent harm from chronic use are increasing in states and countries that have relaxed laws on use. Unintentional edible ingestions are shown to increase in regions that legalize and commercialize cannabis products at the retail level. Long-term effects on teenagers regarding psychiatric changes as well as acute gastrointestinal effects from hyperemesis syndrome are well documented in the medical literature. This article provides clinical information on the presentation, evaluation, and management of adverse effects from pediatric and adolescent teen exposures to cannabis seen in acute care and emergent settings.

[
Pediatr Ann
. 2023;52(5):e181–e186.]
Accumulated Short Bouts of Walking in Older Adults With Type 2 Diabetes: Effects on Glycosylated Hemoglobin (HbA1c) and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR)
Authors: Hsu Chin Hsing , Yang Chung Bing , Chen Mei Huang , Tsao Te Hung
Published: May 2023

The current study examined the effects of accumulated short bouts of walking on glycosylated hemoglobin (HbA1c) and homeostasis model assessment of insulin resistance (HOMA-IR) of older adults with type 2 diabetes. Differences in variables between models of accumulated bouts of walking and 10,000 steps were also investigated. Sedentary participants (
N
= 38) were randomized into one of three groups: accumulated 10-minute bouts of walking at 100 steps/min (10/100MW), accumulated 10,000 steps (10KS), or control. HbA1c, HOMA-IR, blood lipids, and cardiorespiratory fitness (VO2max) were assessed before and after the intervention. VO
2
max, HbA1c, and HOMA-IR in the 10/100MW and 10KS groups showed significant and comparable improvements postintervention compared to preintervention (
p
< 0.05). Furthermore, the change in average daily step count was significantly associated with the change in HbA1c of the two walking groups (
r
= −0.61 for 10KS and
r
= −0.63 for 10/100MW;
p
< 0.05). Accumulated short bouts of walking at 100 steps/min and 10,000 steps daily improved HbA1c and HOMA-IR of older adults with type 2 diabetes. [
Research in Gerontological Nursing, 16
(5), 250–258.]
A "nonlinear duality" approach to $ W_0^{1, 1} $ solutions in elliptic systems related to the Keller-Segel model
Authors: Boccardo Lucio
Published: May 2023

In this paper, we prove existence of distributional solutions of a nonlinear elliptic system, related to the Keller-Segel model. Our starting point is the boundedness theorem (for solutions of elliptic equations) proved by Guido Stampacchia and Neil Trudinger.
Anticorrosive Carbon-Based Polymer and Epoxy Nanocomposite Coatings
Authors: Madkour Loutfy
Published: May 2023

Carbon is used as a reinforcing phase in carbon-fiber reinforced polymer composites employed in aeronautical and other technological applications. Degradation of composite occurs under polarization in aqueous media. Epoxy-based coatings have gained significant research interest owing to sufficient hydrophobicity, conductivity, water transport behaviour, and corrosion resistance. Furthermore, the anti-corrosive polymer coatings with low nanotube content have shown enhanced surface hydrophobicity and anti-rusting properties in addition to strength, conductivity, and thermal resistance. Also, polymer base coatings assessing the strength of bonding of the coating to the substrate, and salt spray test are common. This book chapter highlights the potential corrosion challenges in multi-material combinations containing carbon-fiber reinforced polymers, the surface chemistry of carbon, its plausible effects on the electrochemical activity of carbon, and consequently the degradation processes on carbon-fiber reinforced polymers.
Corrosion Behaviour of Metallic Biomaterials in Physiological Environments
Authors: Pani Rakesh , Behera Rasmi Ranjan , Roy Sudesna
Published: May 2023

Metals are often used in a wide range of biomedical applications since they have good mechanical characteristics, like higher strength, ductility, and toughness. However, the primary disadvantage of metallic biomaterials is their rapid reactivity, which causes corrosion when exposed to physiological conditions like body fluids. When exposed to body fluids, the metallic biomaterial is subjected to wear and corrosion; hence, the mechanical properties are reduced. Corrosion resistance, which also has a significant impact on biocompatibility, affects the efficacy and longevity of an implant material. In this chapter, the body environment will be carefully examined and the potential impacts of corrosion on the biocompatibility of various biomaterials will be highlighted. The fundamentals of implant failure, recovery, and failure mechanisms will be mentioned, and the most common in-vitro and in-vivo corrosion processes will be discussed. Finally, the different methods for preventing biomaterial corrosion will be emphasised.
Overview of the Properties, Applicability, and Recent Advancements of Some Natural Products Used as Potential Inhibitors in Various Corrosive Systems
Authors: Kumar Ashish , Thakur Abhinay
Published: May 2023

This chapter provides an overview of recent advances in using eco-friendly plant extracts as green corrosion inhibitors for metals and alloys in corrosive mediums, with a focus on literature from the past five years. Characterization techniques, including gravimetric analysis, electrochemical impedance spectroscopy, kinetic and adsorption parameters, computational analysis, and surface morphologies techniques, are discussed to provide insights into the inhibition mechanism and the morphological configuration. This chapter will give the audience a better understanding of the properties, applicability, and recent developments in the utilization of natural products as corrosion inhibitors in several corrosive systems.
Novel Bio-Based Green and Sustainable Corrosion Inhibitors
Authors: Rbaa Mohamed , Galai Mouhsine , Berdimurodov Elyor , Tüzün Burak , Touhami Mohamed Ebn , Zarrouk Abdelkader , Lakhrissi Brahim , Elgendy Amr
Published: May 2023

Development of non-toxic and sustainable corrosion inhibitors is greatly needed, in view of these several forms of green corrosion inhibitors natural Chitosan oligosaccharide gained substantial advancement. In this book chapter, the Chitosan oligosaccharide was modified with an 8-hydroxyquinoline derivative to develop a novel bio-based, green, and sustainable mild steel corrosion inhibitor. Fourier transform infrared spectroscopy and nuclear magnetic resonance were used to characterize the modified oligosaccharide. Electrochemical measurements as well as theoretical investigations have been used to examine the anti-corrosion ability of developed chitosan. Electrochemical results confirm that the modified Chitosan oligosaccharide is a mixed type of inhibitor for mild steel. The experimental results have been in agreement with the theoretical study, which has shown that the developed material exhibits the excellent anti-corrosive activity for mild steel in Hydrochloric acid.
Corrosion Inhibition Studies of Synthesized Oleic Sources-Based Green Inhibitors From Agro-Industrial Waste
Authors: Sotelo Oscar , Henao John , Vazquez-Velez Edna , Poblano-Salas Carlos Agustin , Martinez-Valencia Horacio
Published: May 2023

Now, the use of corrosion inhibitors is an effective method to mitigate the corrosion in hydrocarbon extraction and transportation pipelines. Crude oil has several corrosive species, which includes chloride, carbon dioxide, and hydrogen sulphide. Organic type corrosion inhibitors are frequently used to prevent the metallic surface's corrosion due to the mechanism of adsorption related to the displacement of water molecules and the formation a monomolecular hydrophobic layer. With the aim of increasing the inhibition efficiency and obtaining a sustainable corrosion inhibitor, vegetables oils are extracted from agro-industrial waste such as rice, coffee, palm, avocado, etc., and have been used to synthesize a new generation of inhibitors, namely, green corrosion inhibitors, which are cheaper and environmentally friendly. Hence, the purpose of this chapter is to explain the concepts and fundaments about corrosion inhibitors based on imidazoline derivates of natural oils and include information on synthesis and electrochemical performance of a green corrosion inhibitor.
Performance of Benzimidazole Derivatives as Potential Corrosion Inhibitors in Phosphoric Acid Solutions
Authors: Ech-chihbi Elhachmia , Salim Rajae , Ouakki Moussa , Moussaif Ahmed , Rais Zakia , Taleb Mustapha
Published: May 2023

The use of organic compounds as corrosion inhibitors is one of the effective and economical methods to reduce corrosive attacks on metallic materials. In this work, the inhibition ability of two benzimidazole derivatives (SHA and BBC) against the corrosion of mild steel in Phosphoric acid solution was studied using electrochemical techniques, Scanning Electron Microscopy, Energy dispersive X-ray analysis, and Density Functional Theory method. The Potentiodynamic Polarization measurements indicate that the synthesized inhibitors are effective mixed-type inhibitors. SEM/EDX analysis strongly supports the obtained results and confirms the existence of barrier film on the metal surface.
Analyzing the Electrical Signals to Understand the Corrosion Presence in Dissimilar Spot Welds Using Austenitic Stainless Steels and Carbon Steels
Authors: Singgaran Nachimani
Published: May 2023

Welding austenitic stainless steel (ASS) together with carbon steel (CS) is a common practice in spot welding research, but there is a lack of information about the effect of corrosion pertaining to the dynamic resistance, and therefore some surface-corroded carbon steel plates are intentionally welded together with 304L austenitic stainless-steel plates. The welded samples underwent the tensile shear test, hardness test, metallurgical observation, and electrical signal interpretation. Bonding strengths and hardness distributions are both significantly affected by corrosion presence, which reduces the weld strength in overall measure. Microscopic examinations show that the corrosion has randomly scattered around the vicinity of weld nuggets while the electrical signal distinguishes the corroded weld over good welds in terms of electrical resistances.
Molecular Dynamics Simulation of Shock Wave Propagation in Aluminum Single Crystal
Authors: Ju Yuan Yuan , Zhang Lei
Published: May 2023

The characteristics of shock wave propagation in aluminum single crystal are simulated by using the molecular dynamics (MD) method based on the
embedded atom method
(EAM) potential function. The structure of the shock front and the Hugonoit relation are obtained. The simulated results show that a two-wave structure exists in the aluminum single crystal for the particle velocity bellower than 2 km/s and the velocity of the elastic wave increases slightly with the shock loading. While only plastic wave exists in the aluminum single crystal for the particle velocity higher than 2 km/s and the width of the shock front decreases by exponent with the normal stress. The MD simulation results are basically consistent with the experimental results.
Optimization of Ultrasonication Time and Amplitude to Obtain Microbial Nanocellulose with High Degree of Crystallinity
Authors: Nubatonis Lesybeth M. , Hartoto Liesbetini , Warsiki Endang , Syamsu Khaswar
Published: May 2023

The production of microbial nanocellulose implicates physical and mechanical methods such as the application of ultrafine grinders and ultrasonicators. Nano-sized microbial cellulose must contain high crystallinity to be utilized as a filler in nanocomposite polymers. This research aimed to optimize the processing time and amplitudes of the ultrasonication process to stimulate nano-sized microbial cellulose with high crystallinity. In this analysis the Surface Responses Method was used, that is Central Composite Design (CCD) with two factors, that is processing time (X1 = 30, 60, and 90 minutes) and ultrasonication amplitude (X2 = 70, 80, and 90 %) to the degree of crystallinity. The results indicated the optimum point was obtained at a combination of 60 minutes of processing time and 80% amplitudes with the highest degree of crystallinity of 76.23%. The Fourier Transform Infra-Red spectrum at wavenumbers 3340 cm-1 to 2899 cm-1 showed the characteristics of absorption bands in the form of carboxyl groups and hydroxyl groups, which indicate the existence of cellulose compounds. The scanning electron microscope showed the surface morphology of the ultrafine grinding microbial cellulose fibers was denser.
Neurosyphilis in a young man having HIV infection, blurring of vision and skin rash
Authors: Pagaddu JV , Valencia JC
Published: May 2023

We report a 22-year-old homosexual man, a known case of HIV-1 infection but non-compliant to medications, who presented with a 5-month history of progressive painless non-pruritic coin-shaped skin lesions and recent gradual bilateral blurring of vision. His history divulged a primary syphilitic event 1 year prior to the present clinical manifestations. Investigation led to the diagnosis of neurosyphilis with ocular involvement with concurrent signs of secondary syphilis. Treatment with aqueous crystalline penicillin G, ophthalmic steroid and tropicamide drops, and topical emollients resulted in significant clinical improvement of ocular symptoms and skin lesions. The diagnosis of neurosyphilis requires a high degree of clinical suspicion and should be included in the differential diagnosis of unexplained ocular symptoms, particularly in men who have sex with men and HIV-infected patients. This is necessary for the early diagnosis, appropriate management, and good outcome of these patients.
Development of a Drug Management Performance Application: A Needs Assessment in Indonesia
Authors: Faradiba  , Satibi  , Lazuardi Lutfan
Published: May 2023

Objectives: This study assessed the current state of pharmacy management information systems in Indonesia and systematically determined the improvements needed from the stakeholders’ perspective.Methods: This descriptive study used focus group discussions and observations in 13 institutions, and 17 respondents were selected by purposive sampling. The PIECES (performance, information, economy, control, efficiency, service) framework was used to help identify needs. The research was conducted from September 2021 to November 2021 at primary health centers and health offices in Yogyakarta, Indonesia and involved pharmacists and information systems staff.esults: There was no standardized information system in place to support drug management and no format or rules for drug labeling (performance). Pharmacists were not able to provide non-prescription services outside the pharmacy warehouse (information). A new system needs to be developed, and budget availability needs to be determined (economy). System security decreases when users share accounts (control), and the existing systems have not been integrated as needed (efficiency). It is first necessary to plan and support regulations for system development (service). The authors formulated a recommended drug labeling format and a proposed system integration plan.Conclusions: The development of an information system to support drug management is eagerly awaited by pharmacists in Indonesia to assist in their work. Further research on the development and implementation of an information system is needed to improve the quality of drug management at primary health centers.
Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus Images
Authors: Septiarini Anindita , Hamdani Hamdani , Setyaningsih Emy , Junirianto Eko , Utaminingrum Fitri
Published: May 2023

Objectives: The optic disc is part of the retinal fundus image structure, which influences the extraction of glaucoma features. This study proposes a method that automatically segments the optic disc area in retinal fundus images using deep learning based on a convolutional neural network (CNN).Methods: This study used private and public datasets containing retinal fundus images. The private dataset consisted of 350 images, while the public dataset was the Retinal Fundus Glaucoma Challenge (REFUGE). The proposed method was based on a CNN with a single-shot multibox detector (MobileNetV2) to form images of the region-of-interest (ROI) using the original image resized into 640 × 640 input data. A pre-processing sequence was then implemented, including augmentation, resizing, and normalization. Furthermore, a U-Net model was applied for optic disc segmentation with 128 × 128 input data.Results: The proposed method was appropriately applied to the datasets used, as shown by the values of the F1-score, dice score, and intersection over union of 0.9880, 0.9852, and 0.9763 for the private dataset, respectively, and 0.9854, 0.9838 and 0.9712 for the REFUGE dataset.Conclusions: The optic disc area produced by the proposed method was similar to that identified by an ophthalmologist. Therefore, this method can be considered for implementing automatic segmentation of the optic disc area.
Angélique Rougon: une déclinaison romanesque de l’enfant sauvage. Pour une lecture anthropologique du Rêve d’Émile Zola
Authors: Drouot Fanny
Published: May 2023

Angélique Rougon est le personnage principal du Rêve, roman atypique du cycle des Rougon– Macquart, parce qu’il a été conçu initialement par son auteur comme radicalement différent du reste de son oeuvre. Il prévoit ainsi pour son héroïne un destin heureux, en la faisant passer du statut d’enfant abandonnée à celui d’épousée triomphante. Pour autant, le conte, pensé comme un projet réussi de socialisation, tourne court et ce changement d’orientation fait du roman le siège d’une double tension: tension dans la création littéraire, parce qu’il manifeste un écart entre le plan et le texte final, et tension d’ordre anthropologique, parce qu’il remet ainsi en question la réalité du passage heureux d’un état symboliquement sauvage à un milieu défini par sa culture ancestrale.

Angélique Rougon: a novelistic version of the savage child. An anthropological reading of Emile Zola’s Le Rêve
Angélique Rougon is the main character from Le Rêve, a novel from Emile Zola’s Rougon–Macquart cycle, atypical because the author originally conceived of it in a way radically different from the rest of his work. He promises his heroine a happy destiny by moving her from her abandoned childhood identity to a triumphant marital status. But the tale fails at the same time as the project for a successful socialization, and the novel becomes an expression of two tensions: a literary tension on one side, because of the gap between the first plan and the completed text; and an anthropological tension on the other because it questions the possibility of a happy evolution from a symbolical savage state to an environment defined by its ancestral culture.
Wartościowanie dokumentacji — pomiędzy potrzebami administracji a oczekiwaniami nauki
Authors: Jaskółka-Leśniak Katarzyna
Published: May 2023

Wartościowanie dokumentacji jest istotnym procesem mającym wpływ na tworzenie źródeł do badań naukowych. Artykuł omawia zderzenie potrzeb administracji i oczekiwań nauki na gruncie oceny wartości archiwalnej dokumentacji przeprowadzanej przez archiwa państwowe. Pokazano w nim dwa podejścia do oceny wartości dokumentacji wynikające z jej przydatności do celów użytkowych lub naukowych, a także trudności przy przeprowadzaniu selekcji materiałów archiwalnych. Przedstawiono także postulaty w zakresie roli pracownika nadzoru archiwalnego w procesie wartościowania, mające na celu pogodzenie interesów nauki i potrzeb urzędowych.

Evaluating documentation — between the needs of administration and the expectations of science

Evaluating documentation is crucial for the process of creating sources for scientific studies. The paper discusses the clash between the needs of administration and the expectations of researchers regarding the assessment of documents’ archival value conducted by state archives. It demonstrates two approaches towards evaluating documentation resulting from its usefulness for scientific or practical applications, as well as difficulties concerning the selection of archival materials. It also proposes a role for archive supervisors in the evaluation process, which should balance the needs of science and those of administration.
Usefulness of computed tomography performed after forensic autopsy in the diagnosis of the battered child syndrome: a case report
Authors: Skowronek Rafał , Ptak Damian , Pilch-Kowalczyk Joanna
Published: May 2023

Diagnostic imaging methods routinely used in clinical practice (mainly multi-slice computed tomography, CT) are increasingly entering forensic practice, also in Poland. Typically these exams are performed prior to an appropriate external examination and autopsy. The aim of the study is to present a case in which computed tomography examination performed only after forensic medical autopsy turned out to be useful in the diagnosis of an abused child syndrome. The CT examination showed, inter alia, nighstick injury/fracture of the ulna in its distal part, and deformation of the base of the phalanx of the distal finger of the fourth left hand, corresponding to a fracture/crush. Post-mortem imaging may be useful in the case of a suspected abused child syndrome.
Postęp czy regres w działalności naukowej archiwów państwowych? Garść refleksji
Authors: Mazur Hubert
Published: May 2023

Celem artykułu jest próba odpowiedzi na pytanie, czy w obecnych czasach możemy mówić o regresie czy raczej o postępie w działalności naukowej archiwów. W polskiej literaturze brak kompleksowych opracowań poświęconych aktywności naukowej archiwów państwowych. Do jej podejmowania obligują lakoniczne zapisy ustawy o narodowym zasobie archiwalnym i archiwach oraz statuty tych instytucji. Przejawem pewnego kryzysu działalności naukowej archiwów jest jej mylenie lub utożsamianie z aktywnością popularyzatorską czy edukacyjną. Duże znaczenie dla postępu lub regresu w omawianym obszarze ma polityka prowadzona przez poszczególnych naczelnych dyrektorów archiwów państwowych, która bywa niespójna i bardzo zmienna. Aktywność naukowa polskich archiwów pośród pozostałych ich zadań jest słabo widoczna w działalności poszczególnych archiwów państwowych. Informacje o niej rzadko pojawiają się na stronach internetowych archiwów wprost. Są również zmarginalizowane w wadliwie skonstruowanych sprawozdaniach rocznych. Tezy o kryzysie w omawianej materii nie potwierdzają natomiast rosnące liczby publikacji (w tym także czasopism) wydawanych przez archiwa oraz referatów wygłaszanych przez ich pracowników na konferencjach naukowych.

The research activity of state archives — progress or decline? A handful of observations

This paper examines the research activity of archives and seeks to answer the question: are archives making progress in this area or are they actually taking a step back? In the Polish literature, there are no comprehensive studies dedicated to the research activity of state archives. However, pursuant to the brief provisions of the Polish act on the national archival fond and archives, as well as the articles of associations of state archives, these institutions are obliged to undertake such activity. One symptom of decline is conflating or identifying the research activity of archives with their cultural or educational undertakings. One factor that greatly affects the progress or decline in the discussed area are the policies implemented by heads of individual branches of state archives, as these tend to be inconsistent and unpredictable. On state archives’ websites, mentions of research activity of Polish archivists are barely noticeable among their other tasks. Also, state archives very rarely use their own websites to directly communicate their research activities. These activities are marginalized in defectively designed annual reports on the activity of archives. However, the argument that archives are undergoing a crisis in terms of research can be challenged by the growing number of publications (including journals) by the archives, as well as papers presented by their employees at academic conferences.
Investigation of the aerosol's optical properties over the dust prevalent semi-arid region at Jaipur, northwestern India
Authors: Solanki Ranjitkumar , Pathak Kamlesh
Published: May 2023

Jaipur is a key site to study Aerosol Optical Depth (AOD) due to unpredictable variation of atmospheric Aerosols particles in the recent years. Aerosols Optical Depth (AOD) and Angstrom Exponent (AE) were investigated over the semi-arid region, Jaipur (26.9124° N, 75.7873° E) Northwestern India during the April-2009 to December-2017 utilizing AERONET CIMEL sun-photometer level-2 data for aerosols spatial and temporal characteristics. The Aerosols Optical Depth AOD500 nm, AOD440 nm, and AOD340 nm were observed maximum in July-2011 and minimum observed in March-2013. The monthly mean Angstrom Exponent (AE) was maximum (1.53 ± 0.43) for 500-870 nm, (1.49 ± 0.4) for 440-870 nm, and (1.19 ± 0.32) for 340-440 nm in September 2011, while the lowest value recorded (0.26 ± 0.12) for 340-440 nm, (0.16 ± 0.08) for 440-870 nm and (0.15 ± 0.07) for 500-870 nm during June 2014. The backward trajectories analysis was performed using the Hybrid Single-Particle Lagrangian Integrated Trajectories (HYSPLIT) model to determine the sources of large aerosol loadings over the Jaipur region, and air mass simulations from the back trajectory, suggest that the Thar desert northwestern part of India is the source of highest aerosols dust particle over the study area during the pre-monsoon season.
Exploring digital services performance and issues in the developing countries.
Authors:   , Naeem Muhammad
Published: May 2023

PhD by publication is based on published work. As such, this thesis is based on seven published articles, and one article that is accepted at the time of writing. The data for these articles were collected from customers and professionals. The aim of the research was to identify and address issues with digital banking services to improve banking performance. Thus, this reflective critical commentary reflects on 8 journal articles published as part of the PhD process. This reflective project journey encompasses insights, knowledge, information, understandings, and judgements on the overall path to achieving the research aim. Consequently, insight from the reflective report is part of the process of developing a contribution to knowledge. The reflective critical commentary to follow includes a reflection on gaps in knowledge, methodological choices, and contributions to knowledge in terms of each of the articles. The overall focus of the reflective project considers the flow and connectivity of the publications as steppingstones to achieve one common aim through the publication of a series of the articles.
An update on proliferative glomerulonephritis with monoclonal immunoglobulin deposits in pediatric patients
Authors: Hiser Wesley , Xing Guolan , Zhou Xin Jin
Published: May 2023

Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) was first described by Nasr et al. in 2004 with a subsequent study composed of a larger patient cohort a few years later [1,2]. Although more commonly occurring in older adults, PGNMID has since been reported in a wide range of age groups including children [3-5]. PGNMID is categorized as a monoclonal gammopathy of renal significance (MGRS), and is additionally included in the recently expanded concept of monoclonal gammopathy of clinical significance (MGCS), which encompasses disorders of any organ system related to underlying plasma cell or B-cell clones [6]; however, most patients with PGNMID do not show evidence of a circulating monoclonal protein or clonal plasma cell proliferation, and monoclonal gammopathy has not been reported in any pediatric patients with the disease. Herein we briefly discuss the clinical and histopathologic features of PGNMID, as well as advances in our understanding of the pathogenesis and clinical course of the disease.
High-LET targeted microbeam irradiation induces local chromatin reorganization in living cells showing active basal mechanisms at highly complex DNA damage sites
Authors: Schwarz Benjamin , Sammer Matthias , Matejka Nicole , Rudigkeit Sarah , Reindl Judith
Published: May 2023

DNA repair eukaryotic cells have additional protective mechanisms that avoid uncontrolled interaction of different parts of the chromatin and damaged regions. Key factors here are the regulation of chromatin density and mobility. The 4D (temporal and spatial) organization of chromatin is controlling this security barrier by regulating the accessibility of genes, flexibility of DNA, and its ability to move inside the nucleus. How this regulation mechanisms are involved in DNA repair upon radiation damage is until now rarely known but an important part to understand the enhanced effectiveness of high linear energy transfer (LET) particles. The damage recognition via PARP1 and the subsequent chromatin decondensation via PARylation is a crucial step in the DNA damage response (DDR). Upon We used the SNAKE microbeam with a beam spot size of <1 µm to induce highly localized DNA damage in living cells using 55 MeV Carbon ions to investigate the chromatin rearrangements in the early stage of DDR. The nuclei were irradiated with a cross pattern consisting of 1000 ions per spot and 25 spots per cell either with one (11 000 Gy), two (22 000 Gy), or three crosses (33 000 Gy). The chromatin rearrangement was imaged live for several minutes after irradiation at the beam using SiR chromatin stain. Upon 91% of the cells show a localized decondensation starting from a few seconds up to minutes after irradiation. The chromatin is decondensed by 6%-8% in the beam path with a local condensation at the edges of up to 8%. Our results suggest that chromatin decondensation is a fast process in the first few seconds after damage induction. Furthermore, decondensation status does not change over minutes, which gives evidence that this process and therefore DDR is paused or even stopped. In combination with the existing knowledge about early reactions to damage induction our data support the model of PARP induced chromatin decondensation. Furthermore, it is evident that also ultra-high doses of radiation are, in first place not able to inactivate initial basal mechanisms as response to damage induction.