bluuebunny/crossref_metadata_2025 huggingface dataset:
The cost–effectiveness, of pegcetacoplan compared with ravulizumab for the treatment of paroxysmal nocturnal hemoglobinuria, in a UK setting
Authors: Hakimi Zalmai , Wilson Koo , McAughey Eoin , Pochopien Michal , Wojciechowski Piotr , Toumi Mondher , Knight Chris , Sarda Sujata P , Patel Nikita , Wiseman Catherine , de Castro Nuno Pinto , Nazir Jameel , Kelly Richard J
Published: July 2022

Aim:Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder characterized by hemolytic anemia, bone marrow failure and thrombosis. We evaluated, the cost–effectiveness of pegcetacoplan, a novel proximal C3 inhibitor, versus ravulizumab in patients with PNH and hemoglobin levels <10.5 g/dl despite eculizumab treatment in the UK healthcare and social services setting.Materials & methods:A Markov cohort framework model, based on the data from the pivotal trial of pegcetacoplan (PEGASUS/NCT03500549), evaluated lifetime costs and outcomes. Patients transitioned through 3 PNH hemoglobin level/red blood cell transfusion health states.Results:Pegcetacoplan provides lower lifetime costs/greater quality-adjusted life years (£6,409,166/14.694QALYs, respectively) versus ravulizumab (£6,660,676/12.942QALYs).Conclusion:Pegcetacoplan is associated with enhanced anemia control, greater QALYs and reduced healthcare costs versus ravulizumab in the UK healthcare and social services setting.
Microbiome and Cervical Cancer – A Review
Authors: Devi Anchana , Devi T. Ramani , Pushpa N. , Vijayakumar Dharani
Published: July 2022

Cervical cancer (CC) contributes to 6%-29% of all cancers in women. In India, 527,624 new cases of CC are added every year. India contributes to ¼ of deaths worldwide to CC it occurs often in women around the age of 30 yrs which is contributed by a specific kind of human papillomavirus causes long-term infection and inflammation (HPV) which result in morphological changes in the cells of cervix the region that connect vagina and uterus. Cervicovaginal microbiome is observed to be highly diverse among patients with CC where there is reduced number of Latobacillus spp that leads to dysbiosis and decrease in pH and eventually colonised by other anaerobic bacteria. The shift in community state types (CST) is highly associated with the Human Papillomavirus infection and its further progression to cervical dysplasia or CIN i.e. ‘Cervical intraepithelial neoplasia’ and malignant tumour of the cervix uteri. The purpose of this research is to figure out if there’s a link between the cervico-vaginal microbiota and gynaecological cancer and the review also focuses whether cervical microbiome signatures can predict the severity of infection leading to development of CC? Probiotics can be used as a potential alternative to balance the dysbiosis of the cervicovaginal environment. Hence the review summarizes the current knowledge and the interaction of different bacterial groups with Human Papilloma Virus infection and development of CC.
PENDAMPINGAN DIGITAL MARKETING PADA UMKM PKK KARANGPLOSO VIEW-NGENEP (PROGRAM BEMO “Belajar Marketing Online”)
Authors: Mudrifah Mudrifah , Pramuja Risky Angga
Published: July 2022

Pandemi covid menyebabkan masyarakat membuat inovasi untuk bertahan dalam dunia usaha, khusunya UMKM. Para pelaku usaha dituntut untuk melek teknologi untuk tingkat pemasaran yang lebih luas. Namun, pada desa karangploso masih banyak masyarakat yang belum menggunakan teknologi sebagai sarana pemasaran dan penjualan. Pendekatan yang dilakukan adalah dengan mengenalkan digital marketing kepada masyarakat karena saat ini pemasaran lebih pesat dan rapai pada penjualan online. Tujuan utama dari “digital marketing” adalah pemasaran yang memanfaatkan alat atau media digital untuk menjangkau target konsumen secara cepat, tepat dan luas. Sosialisasi strategi digital marketing dalam bentuk peman- faatan media social sangatlah penting karena dapat memberi pengetahuan kepada para pelaku Usaha Mikro Kecil Menengah. Hasil dari pengabdian ini adalah masyarakat mulai mengenal aplikasi penjualan online, mengetahui cara pemasaran online dan mulai memasarkan produk secara online.
Entangled subspaces and generic local state discrimination with pre-shared entanglement
Authors: Lovitz Benjamin , Johnston Nathaniel
Published: July 2022

Walgate and Scott have determined the maximum number of generic pure quantum states that can be unambiguously discriminated by an LOCC measurement [Journal of Physics A: Mathematical and Theoretical, 41:375305, 08 2008]. In this work, we determine this number in a more general setting in which the local parties have access to pre-shared entanglement in the form of a resource state. We find that, for an arbitrary pure resource state, this number is equal to the Krull dimension of (the closure of) the set of pure states obtainable from the resource state by SLOCC. Surprisingly, a generic resource state maximizes this number.Local state discrimination is closely related to the topic of entangled subspaces, which we study in its own right. We introduce r-entangled subspaces, which naturally generalize previously studied spaces to higher multipartite entanglement. We use algebraic-geometric methods to determine the maximum dimension of an r-entangled subspace, and present novel explicit constructions of such spaces. We obtain similar results for symmetric and antisymmetric r-entangled subspaces, which correspond to entangled subspaces of bosonic and fermionic systems, respectively.
Assessment of the forest land inventory accuracy using aerial laser scanning
Authors: Kovyazin V.F. , Pasko O.A. , Lepikhina O.Y. , Trushnikov V.E.
Published: July 2022

The use of forest resources in the context of globalized markets and implementing new technologies, enhanced competition and increasing environmental restrictions require reliable information. The method of aerial laser scanning opens up great prospects for the state inventory of forests. It is successfully used in many sectors of the economy, but it has not been worked out for state forest inventory. The purpose of the study is assessing the possibility of using aerial laser scanning within the framework of current regulations. The object of the study is a forest area of 11 840 hectares in the Leningrad region. The results of aerial laser scanning are combined with the data of ground-based taxation. It is established that deviations in the accuracy of determining the composition, density, average height and diameter, stand and wood stock are within the limits of permissible standards. It is shown that due to the sufficient accuracy of aerial laser scanning, it can be used effectively at conducting a state forest inventory.
Own way
Authors: Glazyev S. Yu.
Published: July 2022

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Islamic Perspective on the Concepts of Interaction among Multicultural Society
Authors: Mohd Khambali @ Hambali Khadijah , Mohd Paudzi Nur Hidayah , Sultan Mohsen Sallam Abdul Nasser
Published: July 2022

Interaction is an important and necessary action that everyone needs in life. Every human being depends on one another to fulfill their necessary needs. Islam has emphasized interaction through the many revealed verses in the Qur’ān as well as the sunnah of Prophet Muhammad (PBUH). In order to build a positive relationship, many concepts of interaction have been introduced by Islamic scholars specifically as guidance for Muslims that are also universally applicable to the whole nation regardless of different religions and ethnicities. The success in the implementation of these concepts can be proven from the rulings of Prophet Muhammad (PBUH) in Medina. The Constitution of Medina is a great guideline in building a solid united multicultural society. This article aims to explain more on the concepts of interaction according to the Islamic perspective. It also expounds on how this concept significantly impacts creating a peaceful co-existence among multicultural society especially in Malaysia as a multi-adherent society based on tasāmuh, mahabbah, and taʻāmul that underlying the concept of fiqh al-taʻāyush.
“Blessed Are Those Who Hunger and Thirst for Truth”: Biblical Allusions in N. S. Leskov’s Novella “The Vale”
Authors: Fedotova Anna A.
Published: July 2022

N. S. Leskov, Russian classic author of the second half of the 19th century, throughout his work actively turned to the Old and New Testaments, which was expressed in a significant number of biblical quotations and allusions in his works. Until now, there is no separate study on the functioning of biblical “text” in the writer’s prose. Within the framework of the proposed work, borrowings from the Old and New Testaments in one of Leskov’s last large-form works, the story, or, in the author’s definition, the “rhapsody” “The Vale,” are analyzed. The novelty of the study is determined by the fact that it identifies and interprets quotes and allusions from the Psalter, the prophetic books of Baruch and Isaiah, as well as the Gospel of John, used by the writer, which were not previously noticed in literary criticism. The article proves that Leskov’s biblical allusions are not disparate fragments of a “foreign” text, they function in a single semantic field of the work and form its subtext, help the writer convey to the reader the results of his moral and religious searches.
Two Versions of Psalm 143 in Paraphrases of Russian Poets of the Late 18 – First Half of the 19 century
Authors: Korovin Vladimir L.
Published: July 2022

The final verses (12–15) of Psalm 143 (144) are read differently in Greek and Jewish versions: the first is about the temporary well-being of sinners, while the second is about the bliss of the righteous. In the Church tradition, the Greek version, which included all the Patristic interpretations adopted by the Orthodox and Catholics, was considered canonical. The Jewish version in Russia was known from foreign translations until 1822. The first biblical paraphrases in Russian poetry of the 18th century were the paraphrases of Psalm 143, made in 1743 by Lomonosov, Trediakovsky and Sumarokov according to the Greek-Slavic version. This article discusses some later paraphrases of Psalm 143, the authors of which also had to make a choice between two versions of the original text. The example of Lomonosov was followed by N. P. Nikolev, G. A. Pakatsky and V. K. Kuchelbecker, as well as E. V. Karneev. The Jewish version was used by A. M. Kotelnitsky and N. M. Shatrov. The paraphrase of F. N. Glinka was regardless of the discrepancy between two versions of Psalm 143. The most interesting are the poems of Kuchelbecker and Shatrov. The article also clarifies the circumstances of the creation of some paraphrases and notes cases of their textual dependence on the “Psalter in the Russian Language” published by the Russian Bible Society and “Commentary on the Psalter” compiled by Archbishop Irenaeus (Klementievsky).
On the Main Text of the Poem by A. A. Fet “Apollo Belvedere”
Authors: Lukina Valentina A.
Published: July 2022

The article raises the issue of the main text of the poem by A. A. Fet “Apollo Belvedere” (1856). Not published during the poet’s lifetime, it was first published by B. V. Nikolsky in 1901 as a four-stanza text according to an autograph preserved in the so-called first workbook. Then, according to the same autograph (also consisting of four stanzas), it was printed by B. Ya. Bukhshtab. The study of the autograph in the workbook and the corrections contained in it, as well as its comparison with another autograph preserved in Fet’s letter to V. P. Botkin from October 21, 1857, gives good reason to talk about the existence of at least three versions of the poem , each of which consisted of three, not four stanzas. The version of the poem now accepted as the main one is a contamination that combines two versions (early and late) of the second stanza.
HISTORICAL RELATIONS BETWEEN BRAZIL AND PARAGUAY: NEGOTIATIONS AND QUARRELS BEHIND ITAIPU DAM
Authors: Pereira Carneiro Filho Camilo , Esposito Neto Tomaz
Published: July 2022

In the context of Brazil-Paraguay historical relations, the construction of the Itaipu hydroelectric dam on the Paraná River – in the border between the two countries – was one of the most important initiatives (in political, economic and energy terms). The events between Brazil and Paraguay involving the Itaipu project are part of South America's geopolitics. In this sense, the present article will focuses the negotiations that preceded and continued throughout the construction of the plant and the treaties and main events and agreements that established the criteria for the operation of the hydroelectric power plant. The Itaipu Treaty, signed in 1973, provides for the revision of financial clauses by 2023. The present work aims to examine the relations between Brazil and Paraguay throughout history and analyze the impacts of the Itaipu Dam on these relationships. This article is a qualitative research, from the perspective of International Relations and Political Geography, enriched with cartography created by the authors with Arc GIS software.
Mirroring its British masters
Authors: Costa Lima Felipe
Published: July 2022

The Indian state has been adopting controversial policies for countering the Maoist insurgency. Even worse, this behaviour seems to mirror Britishcolonial attitudes against India’s population at some level. Consequently, this article attempts to understand this probable ‘paradoxical’ conduct. Withthe support of the post-structuralist theory, I discuss state and outsourced terrorist practices of the Indian state apparatus against this insurgency. Toreach this goal, first, I try to explicate the concept of state terrorism and its application in India. Then, I analyse the historical development of theMaoist movement and India’s concrete policies of state and outsourced terrorism against this counter-hegemonic movement. I believe the British Raj’scolonial practices have had a deep dialectical influence on India’s state apparatus and major political parties to date. So, this inquiry may clarify thepersistence of colonial practices within India.
Emerging call for cancer family：Qualitative Research on Parents’ Expectation for Children with Cancer
Authors: Minrui Niu , Shuwan Dong , Huicai Wang , Jinrong Chen , Qiufeng Cao , Wenyu Ji , Yongxin Wang
Published: July 2022

Objective：The goal of this research is to understand more
about parents’ expectations for their cancer-affected children.
Methods: A semi-structured interview with 20 families of cancer
children took place in a tertiary, level A general hospital in
Xinjiang.To obtain qualitative data, phenomenological research
methods were used to examine the parents’ short and long-term planning
and expectations. Results: Our findings revealed that the
expectations of parents of children with cancer may be divided into two
broad periods. 1) As part of a short-term strategy. Expectations for
children’s physical and mental health,as well as education and the hope
that children would be able to adjust to social situations, were at the
top of the list. 2) Parents’ long-term expectations were lower in terms
of academic success and career planning, but they were more concerned
about their children’s marriages and the possibility of kids.
Conclusion： Parents were perplexed about their children’s
future path choices when they were diagnosed with cancer, and there was
a significant difference between anticipation and reality. According to
our findings, medical practitioners should make the barriers and
tensions faced by children’s families clearer, aid parents and give
social support and compassionate care to children’s families.
Multi-omics provides insights into genome evolution and betacyanin biosynthesis in halophyte of Suaeda salsa
Authors: Wang Xin , Xia Jiangbao , Bai Junhong , Wang Chen , Yin Shuo , Wang Wei , Liang Jinfeng , Wang Dawei , Yi Xinxin , Dai Shenghong
Published: July 2022

As an important halophyte in the Yellow River Delta, the Amaranthaceae
C3 Suaeda salsa (L.) Pall. has attracted much attention for the
“red carpet” landscape, and could be simply divided into red and green
phenotypes according to the betacyanin content in the fleshy leaves.
However, S. salsa has not been sequenced yet, which limited
people’s understanding at the molecular level. We adopted PacBio-SMRT,
Illumina HiSeq paired-end and Hi-C technique to provide a
chromosome-level genome of S. salsa (2n = 2x = 18 chromosomes),
and the size of this high-quality genome assembly was 445.10 Mb with
scaffold N50 of 47.37 Mb. The assembled genome was reported to have
19,580 genes, of which 99.52% were functionally annotated. Genome
annotation showed 67.12% as the repetitive sequences, with long
terminal repeats (LTR) being the richest (50.74%). Comparative genomics
indicated that S. salsa undergone a WGD event about 146.15
million years ago (Mya), and the estimated divergence time between
S. salsa and S. aralocaspica was about 16.9 Mya. A total
of four betacyanins including betanidin, celosianin II, amaranthin and
6’-O-malonyl-celosianin II were identified and purified in both
phenotypes, while two significantly up-regulated betacyanins (celosianin
II and amaranthin) may be the main reason for the red color in red
phenotype. In addition, we also performed transcriptomics and
metabolomics in both phenotypes to explore the molecular mechanisms of
pigment synthesis, and a series of structural genes and transcription
factors concerned with betacyanin production were selected in S.
salsa.
LCMQSINABM: Design of a Low-power hybrid Consensus Method for QoS-aware Sidechain-based IoT Networks via Augmented Bioinspired computing Models
Authors: Agrawal Shital
Published: July 2022

Security is one of the primary issues in any wireless network deployment, because, wireless nodes are susceptible to a wide-variety of internal & external attacks. These include improper authentication & access control, distributed denial of service (DDoS), sybil, spoofing, spying, masquerading, etc. Securing networks against these attacks requires an immutable, transparent, traceable, and distributed computing security model, that has minimum overheads. Most of these characteristics are fulfilled via use of blockchains, which assist in low-complexity deployment of security & hashing models. But the delay needed to scale these blockchains increases exponentially w.r.t. chain length, due to which researchers split the main blockchain into multiple sidechains. A wide variety of models are proposed by researchers for sidechain formation, and most of them are consensus dependent, which limits the scalability. Moreover, energy needed to mine blocks for these sidechains depends directly on the consensus model, encryption model, hash rules, and length of the blockchain. Thus, models proposed for sidechain formation are context-specific, and have limited scalability performance when used for multiple blockchain types. To overcome these limitations, and maintain high security performance, this text proposes design of a Low-power hybrid Consensus Method for QoS-aware Sidechain-based IoT Networks via Augmented Bioinspired computing Models. This method uses a combination of Proof-of-Work (PoW), Proof-of-Stake (PoS) & Proof-of-Authority (PoA) based consensus models, which assists in reducing its mining delay. The PoW model allows selection of nodes with higher performance, PoS allows selection of nodes with higher stake, and PoA ensures better control of IoT devices. Selection of these consensus models is done via use of an Improved Genetic Algorithm (IGA) model, that evaluates the power needed for mining, and minimizes it using a rule-based method. This is combined with a sidechain creation model, that assists in improving QoS performance via dynamically splitting the main blockchain into performance-specific sidechains. These sidechains are categorized into low-power, low-delay, and high-throughput sidechains, which are formed via Elephant Herding Optimization (EHO) model. Due to combination of IGA for consensus selection, and EHO for sidechain creation, the proposed model is able to reduce energy needed for mining by 15.4% when compared with various state-of-the-art models. It is also able to improve mining speed by 5.3%, while maintaining high security performance under different IoT Network attacks. Due to this performance enhancement, the proposed model is capable of being deployed for a wide variety of low-delay healthcare IoT, high-throughput industrial IoT, and low energy home IoT application deployments.
FINANCIAL INDEPENDENCE OF SMALL COMMUNES IN POLAND’S LUBELSKIE VOIVODESHIP: IMPORTANCE FOR FINANCIAL STABILITY
Authors: Cyburt Agnieszka
Published: July 2022

The aim of the study was to determine the level of financial independence of 81 small communes of Poland’s Lubelskie Voivodship (up to 5,000 inhabitants per commune) and to assess its significance for their financial stability. The following methods were used: literature analysis, ratio analysis and diagnostic survey. Financial data from 2017-2021 was adopted for the analysis. 69 heads of communes participated in the conducted survey. It was established that in the opinion of these leaders, income potential and financial independence are important factors affecting the financial stability of small communes, and their low level poses a threat to this stability. Three ratios were used to assess financial independence. The analyses showed that small communes were characterized by a low level of income independence and a high dependence on revenues transferred from the state budget, which is evident in the value of the expenditure independence ratio achieved.
The Use of Point-of-Care Bacterial Autofluorescence Imaging in the Management of Diabetic Foot Ulcers: A Pilot Randomized Controlled Trial
Authors: Rahma Sara , Woods Janet , Brown Sarah , Nixon Jane , Russell David
Published: July 2022

OBJECTIVE

To estimate comparative healing rates and decision-making associated with the use of bacterial autofluorescence imaging in the management of diabetic foot ulcers (DFUs).

RESEARCH DESIGN AND METHODS

This is a single-center (multidisciplinary outpatient clinic), prospective pilot, randomized controlled trial (RCT) in patients with an active DFU and no suspected clinical infection. Consenting patients were randomly assigned 1:1 to either treatment as usual informed by autofluorescence imaging (intervention), or treatment as usual alone (control). The primary outcome was the proportion of ulcers healed at 12 weeks by blinded assessment. Secondary outcomes included wound area reduction at 4 and 12 weeks, patient quality of life, and change in management decisions after autofluorescence imaging.

RESULTS

Between November 2017 and November 2019, 56 patients were randomly assigned to the control or intervention group. The proportion of ulcers healed at 12 weeks in the autofluorescence arm was 45% (n = 13 of 29) vs. 22% (n = 6 of 27) in the control arm. Wound area reduction was 40.4% (autofluorescence) vs. 38.6% (control) at 4 weeks and 91.3% (autofluorescence) vs. 72.8% (control) at 12 weeks. Wound debridement was the most common intervention in wounds with positive autofluorescence imaging. There was a stepwise trend in healing favoring those with negative autofluorescence imaging, followed by those with positive autofluorescence who had intervention, and finally those with positive autofluorescence with no intervention.

CONCLUSIONS

In the first RCT, to our knowledge, assessing the use of autofluorescence imaging in DFU management, our results suggest that a powered RCT is feasible and justified. Autofluorescence may be valuable in addition to standard care in the management of DFU.
Health and household environment factors linked with early alcohol use in adolescence: a record-linked, data-driven, longitudinal cohort study
Authors: Bandyopadhyay Amrita , Brophy Sinead , Akbari Ashley , Demmler Joanne , Kennedy Jonathan , Paranjothy Shantini , Lyons Ronan , Moore Simon
Published: July 2022

IntroductionEarly alcohol use has significant association with poor health outcomes. Individual risk factors around early alcohol use have been identified, but a holistic, data-driven investigation into health and household environmental factors on early alcohol use is yet to be undertaken.
ObjectivesThis study aims to investigate the relationship between preceding health events, household exposures and early alcohol use during adolescence using a two-stage data-driven approach.
MethodsIn stage one, a study population (N=1,072) were derived from the Millennium Cohort Study (MCS) Wales (born between 2000-2002). MCS data were first linked with electronic-health records. Factors associated with early (<= eleven years old) alcohol use were identified using feature selection and stepwise logistic regression. In stage two, analogous risk factors from MCS were recreated for whole population (N=59,231) of children (born between 1998-2002 in the Welsh Demographic Service Dataset) using routine data to predict the alcohol-related health events in hospital or GP records.
ResultsSignificant risk factors from stage two included poor maternal mental (adjusted odds ratio [aOR]=1.31) and physical health (aOR=1.25), living with someone with alcohol-related problem (aOR=2.16), single-adult household (aOR=1.45), ever in deprivation (aOR=1.66), child's high hyperactivity (aOR=3.57), and conduct disorder (aOR= 3.26). Children with health events, whose health needs are supported (e.g., are taken to the doctor), are at lower risk of early alcohol use.
ConclusionHealth events of the family members and the child can act as modifiable exposures and may therefore inform the development of prevention initiatives. Families with known alcohol problems, living in deprivation, experiencing child behavioural problems and those who are not taken to the doctor are at higher risk of early drinking behaviour and should be prioritised for early years support and interventions to target problem drinking in young people.
Interactive Media Development Using Articulate Storyline-Based Instructional Games for Teaching Fractions
Authors: Adhiana Vina Iman , Yuniawatika Yuniawatika , Ahdhianto Erif , Wantoro Jan
Published: July 2022

This research and development were carried out to produce valid and engaging interactive fractional learning media products using Articulate Storyline-based instructional games. This study used the type of research and development (RD) using the ADDIE model. The research subjects were the fifth-grader of State Elementary School 5 Saptorenggo Malang Regency. The techniques used in this study were validation questionnaires, observation, and interviews. Material experts, media experts, and teachers conducted a validity test to achieve a valid category result. The attractiveness test obtained a very high score and reached the very attractive category. The use of product development can improve student learning outcomes and provide an understanding of fractional material that is known from the value they get when doing practice questions and getting an average score above the Minimum Completeness Criteria. Thus, it can be said that this interactive media falls under the category of being appropriate for use in the learning process and being both valid and interesting. This research employed an Articulate Storyline-based learning game that covers the subject of mathematical fractions
Relationship between academic staff withdrawal behaviours and administrative effectiveness of heads of department of universities
Authors: Azelama Beauty Avoedoya , Osumah Obaze Agbonluae
Published: July 2022

The study examined the relationship between withdrawal behaviours and administrative effectiveness of heads of academic departments of the universities in Edo State Two research questions were raised and two hypotheses were formulated to guide the study. The study adopted the combination of survey method and correlational research design. A sample of 1,100 representing 40 percent of the population was drawn using the multi-stage stratified random sampling technique. The instruments used for the study were Absenteeism of Academic Staff (AASS) and Instrument for Measuring Lateness of Academic Staff (MLASS) and Head of Department Administrative Effectiveness Questionnaire (HODAEQ). Cronbach Alpha reliability was used to determine the reliability of the instruments. Hypotheses 1 and 2 were tested,  using the Pearson Product Moment Correlation Co-efficient. The results of the study showed that: there was a strong, inverse and significant relationship between academic staff absenteeism and administrative effectiveness of the Heads of Department. The study also found that there was a strong, inverse and significant relationship between academic staff, lateness and administrative effectiveness of the heads of department. It was therefore concluded that absenteeism and lateness withdrawal behaviour of academic staff has adverse effect on HOD’s administrative effectiveness. The study consequently recommended among others staff enlightenment on the adverse impact of Academic Staff withdrawal behaviours on Heads of Departments’ administrative effectiveness.
Fashion design education students learning readiness; increase or decrease
Authors: Ernawati Ernawati
Published: July 2022

This study is based on the problem of many students do not have the learning readiness in fashion design education. This study aimed at the influence of pedagogy and learning interest on fashion design education students learning readiness. The total population was 497 students of the Fashion Design Program of Universitas Negeri Padang. The sampling technique used in this study is total sampling. A total of 497 respondents were successfully collected. The data analysis technique used is Partial Least Square Structural Equation Modelling (PLS-SEM). The results showed that: There is a significant effect of pedagogy toward fashion design education students learning readiness and there is a significant effect of learning interest toward fashion design education students learning readiness. What could be said from the result of the study is that good pedagogical abilities of lecturers could be increased fashion design education students learning readiness and high learning interest of students could be increased fashion design education students learning readiness.
Survey of occupational stress among urban school librarians in Nigeria
Authors: Victor-Aigbodion Vera
Published: July 2022

Occupational stress is becoming increasingly common in all categories of workers. Due to the overwhelming demands of library customers, librarians are likely to suffer occupational stress as well.  The objective of this study is to assess the occupational stress of urban school librarians in selected Nigerian public secondary schools. A descriptive survey was conducted and the Occupational Stress Scale (OSS) was used to collect data from 75 urban secondary school Librarians in South-East Nigeria. Means, standard deviations, and analysis of variance were used to analyze the results. Findings suggested that male and female secondary school librarians in the sampled urban secondary schools felt similarly about their occupation's level of stress. In addition, urban school librarians with bachelor's degrees reported higher levels of occupational stress. Another finding showed that urban school librarians who are married showed more occupational stress than those who are single, separated/divorced and widowed. Moreover, no significant differences were found between urban secondary school librarians who worked in mixed or single sex schools for occupational stress. In conclusion, occupational stress is present among urban school librarians in Nigerian public secondary schools. It was recommended that stress management interventions should be tailored to assist these school librarians in managing their level of stress.
DIFFERENTIAL EXPRESSION OF MICRORNAs IN LUNG CANCER: A REVIEW ARTICLE
Authors: Ahmad Omair , Khan Bilal , Armoghan Mohammad , Gautam Swapnil Raj , Saiyyada Zakiya , Siddiqui Zainab
Published: July 2022

MicroRNAs (miRNAs) are small non-coding RNA molecules of approximately 16-24 nucleotide length. The miRNA biogenesis is a 2 step cleavage process mediated by Dorsha and Dicer. The nuclear cleavage by Dorsha / DiGeorge syndrome critical region 8 (DGCR8) generates 60-70 nucleotide long precursor microRNA (pre-miRNA). Furthermore, the pre-miRNAis exported to the cytoplasm by exportin 5 to be cleaved by Dicer. This resultant miRNA is further processed to generate a mature miRNA and get assembled into a RNA-induced silencing complex (RISC). Hence leading to transcriptional repression of the target mRNAs. It has been reported that one miRNA may target many genes accounting from a few to as many as thousands. Lung cancer (LC) ranks third worldwide and is marked by poor prognosis. The early staged LC patients usually exhibit no symptoms and the condition worsens till the time of first diagnosis. Therefore, studies are required to outline good early detecting and surveillance biomarkers for LC. Several evidences support the role of miRNAs in the pathogenesisof LC. They show differential expression pattern i.e. may be either upregulated or downregulated. The oncogenic miRNAs remain upregulated while the tummor suppressive miRNAs remain downregulated. In LC miRNAs are the important factors for tumour initiation, differentiation, apoptosis, proliferation as well as tumor progression. Thus, this review article focuses on the diagnostic significanceof miRNAs in LC.
PREGNANCY WITH PINK BLOOD: A CASE REPORT
Authors: Kumari Shweta , Ahmad Ayesha , Khatoon Fareha , Nishad Suman , Saambhavi Saambhavi
Published: July 2022

A24 year old female P1L1 presented to our hospital on first post operative day of emergency caesarean delivery with complaint of fever with chills and rigors. The per-operative notes showed the presence of thick pinkish maternal blood when compared to cord blood, which turned opaque white while sampling. On examination she had pallor and raised blood pressure. Her lipid levels were very high and ultrasound showed bilateral mild pleural effusion with minimal ascites with increase echogenicity of peripancreatic fat. She was started on injectable antibiotics following which she improved in symptoms. She was also started on fenofibrate and orlistat following which her lipid profile improved and the blood stopped turning opaque white and she was then discharged against medical advice due to financial constraints.
LYMPHOEPITHELIOMA LIKE CARCINOMA OF URINARY BLADDER: A RARE CASE REPORT
Authors: Jaiswal Jyoti , Shukla Shivangi , Shukla Garima , Parveen Huma , Chaudhary Reeta , Lal Nirupma
Published: July 2022

Urinary bladder neoplasm is the 10th most common cancer in the world, predominantly affecting males. Nowadays incidence of urinary bladder carcinoma in female has increased. It is a uncommon type carcinoma of urinary bladder. It resembles to non-keratinizing carcinoma of nasopharynx. This study report a case of 65 years old male presented with painless gross hematuria for 3 weeks. Patient was a known case of Meckel's diverticulum. Ultrasonography and cystoscopy showed a mass on lateral wall of urinary bladder measuring 3x3 cm . A radical cystectomy of the urinary bladder tumor was done. He was diagnosed as case of lymphoepithelioma like carcinoma of urinary bladder along with benign prostate hyperplasia and Meckel's diverticulum was made with stage 2.According to the WHO classification criteria, Lymphoepithelioma like carcinoma is a subtype of undifferentiated carcinomas. Immunohistochemical stains are helpful to differentiate Lymphoepithelioma from primary lymphoma of the bladder. Differentiation of LELCB from urothelial carcinoma is important, since it has better prognosis compared to pure urothelial carcinoma. It is important to diagnose this neoplasm for therapeutic as well as prognostic purpose.
Strategi Pemasaran Pendidikan dalam Meningkatkan Citra Sekolah
Authors: Fradito Aditia , Suti'ah Suti'ah , Muliyadi Muliyadi
Published: July 2022

AbstractThe purpose of research is the analysis of marketing strategies in enhancing the image. This study is a qualitative research using a case study approach. Techniques of collecting data through observation, documentation and interview . The study found that elementary school education services Islam Surya Buana prioritize its efforts on the fulfillment of expectations and customer satisfaction. Marketing education in improving the image of the school performed in some of the strategies; direct strategy and indirect strategy, difference strategy, financing strategy. However, an effective strategy in SD Islam Surya Buana is to show proof of the quality of graduates and image building service satisfaction through word of mout. The impact of marketing strategy for imaging in SDI Surya Buana are; a). The high of customer loyalty (public understanding). b). Public confidence is getting stronger (public confidence), c). The existence of public support (public support), d). The establishment of effective cooperation between schools and parents (public corporation). Key Words: Service, service marketing,  education marketingAbstrakTujuan penelitian adalah analisis strategi pemasaran dalam meningkatkan citra. Penelitian ini merupakan penelitian kualitatif menggunakan pendekatan studi kasus. Tehnik pengumpulan data melalui observasi, dokumentasi dan wawancara mendalam. Hasil penelitian menemukan bahwa layanan jasa pendidikan di SD Islam Surya Buana memprioritaskan pada upaya terpenuhinya harapan dan kepuasan pelanggan. Pemasaran pendidikan dalam meningkatkan citra dilakukan sekolah dalam beberapa strategi; strategi langsung, strategi tidak langsung, strategi perbedaan, strategi pembiayaan. Namun demikian stategi yang efektif di SD Islam Surya Buana adalah dengan menunjukkan bukti kualitas lulusan dan membangun citra kepuasan layanan melalui berita dari mulut ke mulut. Dampak strategi pemasaran dan implikasinya terhadap pencitraan di SDI Surya Buana adalah; a). Tingginya loyalitas pelanggan pengguna jasa pendidikan. b). Kepercayaan masyarakat semakin kuat, c). Adanya dukungan masyarakat, d). Terjalinnya kerjasama yang efektif antara sekolah dan orang tua siswa. Kata kunci: Layanan jasa, pemasaran jasa, pemasaran pendidikan
IMPLEMENTASI MANAJEMEN MUTU TERPADU	DI SEKOLAH/MADRASAH
Authors: SAPUTRO ANIP DWI
Published: July 2022

School/Madrasah is the system of education in this country, school/Madrasah has a system of education, such as basic education, objectives, curriculum, methods, patterns student teacher relationship, and so forth. Such a system can be created using an integrated quality management through concepts, strategies and applications. That's all it took the setup process management to achieve educational goals effectively and efisien.Sistem effective and efficient could be in the form of the integrated quality management (MMT). Implementation of Integrated Quality Management in Schools/Madrasah wear integrated quality management (MMT). From the description it can be concluded that the management could dikatan as a process in order to achieve the goal by working together through people and other organizational resources. Management becomes a reference system for mengordinir and control all of the potential that exists within a particular organization. The aim is to arrange everything so well done, accurate and complete. With reference to the quality standards of Government Regulation No. 19 Year 2005 on National Education Standards, which includes the provision of the eight standards, namely: 1) Standard Competency, 2) Content Standards, 3) Processing Standards, 4) Standards of Education and the Workforce, 5) Infrastructure Standards, 6) Standard Management, 7) Financing Standards Education, 8) Education Assessment Standards. Implementation of Integrated Quality Management Schools/Madrasah there are several strategies that can be implemented by the school/madrasah among others, include a self-evaluation to analyze the strengths and weaknesses of the school/madrasah. Based on the evaluation of school madrasah together parents and society determines the vision and mission of the school/madrasah in improving the quality of education or formulate the expected quality and continued with planning school programs/madrasah including financing, with reference to priorities and national policies in accordance with the conditions of the school/madrasah and resources available. Keywords: quality management and the school
GREEN MARKETING STRATEGY: HUBUNGAN GREEN PERCEIVED VALUE DAN GREEN TRUST
Authors: ALAMSYAH DONI PURNAMA
Published: July 2022

Green Marketing Strategy has become the latest strategy for the company, especially for two-wheeled vehicles in Indonesia with innovative environmentally friendly products. It is interesting assessed as innovation in environmentally friendly products has not been applied in Indonesia. So the focus of research studies on the description and influence between the variables in the green perceived value and green trust of consumers for environmentally friendly products. Descriptive and verification combined with survey method in this research with 105 respondents, who are consumers of Honda brand vehicles by using simple linear regression analysis techniques. Results found a good overview on the green perceived green value and green trust. As well as the relationships and the influence of green perceived value to green trust. So to say precisely when companies in Indonesia has used a green marketing strategy in the competitive business. Given the good response to the innovation of products friendly to the environments. Keywords: green perceived value, green trust
Characteristics of Wooden Furniture Drying Machine
Authors:   Department of Mechanical Engineering, Sanata Dharma University, Purwadi Petrus Kanisius , Prasetyadi A.
Published: July 2022

This study aims to determine the characteristics of the electric energy drying machine used to dry wooden furniture. Furniture made of mahogany. The research was conducted experimentally in the wood furniture industry. The size of the wood drying room is 8 m x 6 m x 3 m. The dryer works with a vapor compression cycle using R134a freon and several fans placed in the drying chamber. The drying process uses a closed air system. The total volume of dried wooden furniture is 12.9 m3. The initial moisture content in the wood ranges from 18% to 23%. Wooden furniture is considered dry if the moisture content in the wood furniture is less than 12%. Research gives satisfactory results. The performance of the drying machine or COP is 10.85. The drying time for wooden furniture is about 72 hours.
GENDER INTERACTION BETWEEN COVARIATES IN MANAGING ANXIETY VIA VLOGS
Authors: Shukor Siti Shuhaida , Madzlan Noor Alhusna
Published: July 2022

Background and Purpose: ESL learners found themselves engulfed with extreme anxiety when it comes to speaking in public. This study investigated the use of vlogs in managing anxiety between male and female undergraduate students and examined whether there is an interaction exists between both genders during the intervention that may influence the outcomes.
 
Methodology: This study employed a quasi-experimental design with a total of N=53 (15 males, 38 females) ESL participants from one public university in Malaysia. Before and after the intervention, a set of 'Personal Report of Public Speaking Anxiety (PRPSA) questionnaires were administered. A 2x2 between subjects factorial ANCOVA (or two-way ANCOVA) was computed by controlling the pre-test scores. After controlling for the pre-test as covariate, the two-way ANCOVA was performed to see if there was an interaction impact between gender (male vs female) and treatments (with and without vlogs) in terms of anxiety level scores.
 
Findings: In comparison to the control group, the experimental group performed better with F(1, 48)=6.695, p<.05, which showed that undergraduate students in the experimental group displayed less anxiety when using vlogs as compared to the treatment group. However, there was no significant difference of gender influence on the effectiveness of vlogs on learners’ anxiety with F(1, 48)=1.552, p>.05, Eta-squared = .03 when using vlogs. Nonetheless, there was a significant interaction between treatment groups and gender with F(1,48)=5.22, p<.05 which indicated that the relationship between the covariate and the dependent variable is different for each treatment group.
 
Contributions: This study is hoped not only to encourage ESL educators to make use of vlogs in their teaching and learning, but also to inform researchers with similar interest to consider the existence of covariates of the participants that might have impacted the research outcomes.
 
Keywords: Speaking, anxiety, covariates interaction, gender differences, vlogs.
 
Cite as: Shukor, S. S., & Madzlan, N. A. (2022). Gender interaction between covariates in managing anxiety via vlogs.  Journal of Nusantara Studies, 7(2), 1-20. http://dx.doi.org/10.24200/jonus.vol7iss2pp1-20
FUNDAMENTAL ELEMENTS IN SUSTAINING INTER-RELIGIOUS HARMONIOUS RELATIONS UNDER ISLAMIC PERSPECTIVES IN THE AGE OF NEW MEDIA
Authors: Mohd Khambali @ Hambali Khadijah , Ghazali Alwani , Senin Nurhanisah
Published: July 2022

Background and Purpose: Inter-religious harmony is crucial in maintaining peaceful co-existence and national stability of a multiracial and multi-religious society. The existence of minor racial or religious tension in the society can escalate to a crisis and jeopardise inter-religious relations in this age of new media. The failure to preserve religious harmony may expose the society to conflict and chaos. Thus, this article aims to discuss and elaborate the fundamental elements in sustaining harmony among multi-religious society from Islamic perspective in the age of new media.
 
Methodology: This research employs the qualitative research design. The research method used is content analysis, and the library data that comprises the physical and online books and articles on topics related to religious harmony and new media, was collected from the years 2010 until 2021. Using deductive reasoning, the challenges of new media in the area were identified and solutions proposed.
 
Findings: The findings indicated that the challenges of interreligious harmony in the age of new media are the rapid spread of atheism, religious pluralism, misperception of a religion due to its intra-faith issues, mistaken identity of a religionist versus racist, misunderstanding of ‘izzah as arrogance and misrepresentation of Islam. These challenges can be reduced by applying the fundamental elements to sustain interreligious harmony in Islamic perspective, namely ta`āruf (knowing each other), tafāhum (mutual understanding), ta`āwun (mutual cooperation), takāful (mutual protection), tasāmuḥ (mutual tolerant) and acceptance. Besides, Muslim educators or murabbiyun have to be the prosumers of the new media to continuously teach Islam, and instil iman and adab among fellow Muslims.
 
Contributions:  This article contributes to the foundation of peaceful co-existence in a multi-religious context because the fundamental elements discussed form the basis of fiqh al-ta’ayush or the understanding of co-existence, especially in the age of new media.
 
Keywords: Basis of religious harmony, inter-religious relation in Islam, fiqh al-ta’amul, fiqh al-ta’ayush, religions in the age of new media.
 
ite as: Mohd Khambali @ Hambali, K., Ghazali, A., & Senin, N. (2022). Fundamental elements in sustaining inter-religious harmonious relations under Islamic perspectives in the age of new media. Journal of Nusantara Studies, 7(2), 147-165. http://dx.doi.org/10.24200/jonus.vol7iss2pp147-165