bluuebunny/crossref_metadata_2025 huggingface dataset:
HIV in pregnant women group in the Republic of Guinea: frequency and genetic characteristics
Authors: Balde T.A.L. , Shchemelev A. N. , Ostankova Yu. V. , Boumbaly S. , Valutite D. E. , Davydenko V. S. , Serikova E. N. , Zueva E. B. , Anufrieva E. V. , Skvoroda V. V. , Vasileva D. A. , Esaulenko E. V. , Semenov A. V. , Totolian Areg A.
Published: July 2023

The aim of this study was to assess the prevalence and study of the molecular genetic characteristics of the human immunodeficiency virus in pregnant women of the Republic of Guinea.

Materials and methods. The material for the study was blood plasma samples of 972 pregnant women from the Republic of Guinea. The patients were examined for the presence of HIV infection serological (Ag+Ab) and molecular markers (RNA). For patients with a positive PCR result and a sufficient viral load (>500 c/ml), the genetic sequences of the pol gene fragment responsible for the synthesis of pro and rev proteins were obtained by Sanger sequencing. These sequences were used for phylogenetic analysis and examined for drug resistance mutations.

Results and discussion. 12.96% of patients was positive in ELISA. Among women who were positive in ELISA, RNA was detected in 76.98% of cases, however, in 11 cases, RNA was detected in patients without serological markers of HIV infection, so the incidence of HIV RNA in the entire surveyed population was 11.11%. In the vast majority of cases, the circulating recombinant form 02_AG is found. Based on the analysis, we assume a significant contribution of recombinant forms of HIV to the genetic diversity of the virus in the region under study.

The incidence of DR mutations was quite high (26.80%). The most frequent substitutions were in position 20 of the protease (70.10%, 95% CI 59.96–78.98%), of which the K20I mutation was dominant. In addition, the L10I/V mutation was relatively common, increasing the replication of viruses with other PI resistance mutations. Among the mutations associated with HIV resistance to NNRTIs, a non-polymorphic mutation V179T was found.

Conclusion. An important factor influencing the effectiveness of Prevention of Mother to Child Transmission identified in this study was the high prevalence of PDR among pregnant women in Guinea. The high prevalence of drug resistance mutations found in this study in pregnant women, as well as in ART-naive women, indicates that current regimens in Guinea are insufficient to prevent vertical HIV infection.
The Influence of The Internet As A Source of Online Literature and The Level of Student Plagiarism
Authors: Sukri Muhammad , Damopolii Muljono , Nursalam Nursalam
Published: July 2023

This study aims to describe the level of intensity of internet use as a provider of online literature and the level of plagiarism committed by students. In addition, the significance of the influence of the intensity of internet use as a provider of online literature on the level of student plagiarism is also seen here. The population in this study was all students of the Department of Islamic Religious Education, Faculty of Tarbiyah and Teacher Training, UIN Alauddin Makassar, for the 2019/2020 academic year, totaling 312 people. Using stratified random sampling, 31 people were selected as the sample. Data collection was carried out using a questionnaire and analyzed with descriptive and inferential statistics. The results of this study indicate that first, the measure of the intensity level of internet use as a provider of online literature is included in the moderate qualification, namely the average (mean) of 32.65. Second, the measure of the level of plagiarism among students of the Department of Islamic Religious Education, the Faculty of Tarbiyah, and Teacher Training is included in the moderate qualification, namely the average (mean) of 38.39. Therefore, this article concludes that there is a significant influence between the intensity of internet use as a provider of online literature and the level of plagiarism.
Technological Pedagogy And Content Knowledge: Digitizing 21st Century Learning
Authors: Nurlailli Hidayati  , Hakiman  , Noor Alwiyah
Published: July 2023

This study aims to determine the application of technological pedagogical and content knowledge (TPACK) by teachers in the implementation of Akidah Akhlak subject learning in class XI of Madrasah Aliyah. The research method used is descriptive-qualitative. Data collection in the study was carried out using observation, interview, and documentation techniques. Data validity was carried out using source triangulation and method triangulation techniques. The results showed that the application of TPACK in learning involves the use of technological devices, both non-digital and digital, such as laptops and LCDs, and that teachers are able to use PowerPoint, YouTube videos, and Google Classroom in creating learning materials. Teachers use technology in the classroom to manage learning practices and assess the learning process effectively and efficiently.
DIMENSIONAMIENTO ÓPTIMO DE UN SISTEMA HÍBRIDO DE ENERGÍA SOLAR-EÓLICA Y BANCO DE BATERÍAS UTILIZANDO INTELIGENCIA ARTIFICIAL
Authors: Gualdron Oscar E. , Laguado R Raquel I. , Florez S Elkin G.
Published: July 2023

Para realizar el pronóstico de datos meteorológicos con el fin de realizar un análisis del potencial solar y eólico del aeropuerto Camilo Daza de la ciudad de Cúcuta, redes neuronales multicapa tipo Perceptron configuradas con 9 neuronas de 4-4 capas y 10 tiempos o las iteraciones se utilizan para ajustar las variables de procedimiento de la regresión. Para ello se utiliza la metodología presentada por Jorge Aguilera y Leocadio Hontoria y la distribución de densidad de probabilidad de Weibull, con la intención de garantizar una menor inversión inicial con un uso adecuado y completo del sistema solar, el sistema eólico y el banco de baterías, de modo que que la relación costo/inversión/beneficio sea viable.
MENINGKATKAN HASIL BELAJAR SISWA MELALUI METODE DISKUSI PADA MATA PELAJARAN IPS DI KELAS VIII-1 SMP NEGERI 4 MEDAN
Authors: SIREGAR JURIAH
Published: July 2023

Penelitian ini bertujuan untuk melihat aktivitas  dan prestasi belajar siswa saat bekerja dalam kelompok dikelas pada mata pelajaran IPS Terpadu dengan metode diskusi di kelas VIII-1 SMP N 4 Medan. Awal KBM dilakukan tes hasil belajar (Pretes), dengan data rata-rata 23,6 hal tersebut menunjukkan bahwa rata-rata siswa jarang membaca buku sebelum  pembelajaran disekolah.  Kemudian dilanjutkan KBM, akhir KBM  ke II dan  KBM ke IV dilakukan  tes hasil belajar  Postes I dan Postes II  hasilnya  masing-masing menunjukkan 72,8 dan  85,0. Melihat data tersebut ada perubahan dan perubahan tersebut akibat tindakan guru selama KBM pada Siklus II. Walaupun  hasil belajar siswa tuntas tapi data tersebut tuntas minimum ini akibat siswa belum terbiasa belajar saling membantu. Selama KBM siswa kelihatan  lebih tertarik terhadap mata pelajaran dan keingintahuannya sedikit lebih tinggi yang mengindikasikan bahwa ketertarikan siswa terhadap pelajaran  karena keingintahuannya. Ini merupakan efek dari  metode diskusi yang cukup menumbuhkan sikap ingin tahu dan minat terhadap pelajaran.   Kata kunci : Metode Diskusi, Hasil Belajar
PENGELOLAAN MODEL PEMBELAJARAN TGT DALAM MENINGKATKAN MOTIVASI BELAJAR IPS KELAS VII-5 SMP NEGERI 3 PERCUT SEI TUAN
Authors: Br. Ginting Idawati
Published: July 2023

Abstract: Management of Cooperative Learning Model to Improve Learning Motivation TGT IPS In Class VII-5 SMP Negeri 3 Percut Sei Tuan. This study aims to determine how the implementation of cooperative learning model TGT type in improving student motivation .. The research process was conducted in two cycles each of 4 meetings. The results showed an increase in students' motivation high motivation of 16.67% with a mean achievement 43.99% of indicators of motivation to learn in the initial observation, increasing became 33.33% with the average achievement of 46.40% at mid-cycle I and became 61.11% with the average achievement of 69.62% at the end I. in the mid-cycle second cycle students who are highly motivated rose to 80.56% with the average achievement of 75.09%, and at the end of the cycle II reached 91.67% with a mean of 80.99% achievement of indicators of students' motivation. Keywords : Motivation, Learning Methods Abstrak : Pengelolaan Model Pembelajaran Kooperatif Tipe TGT Dalam Meningkatkan Motivasi Belajar IPS Di Kelas VII-5 SMP Negeri 3 Percut Sei Tuan. Penelitian ini bertujuan untuk mengetahui cara penerapan model pembelajaran Kooperatif Tipe TGT dalam meningkatkan motivasi belajar siswa.. Proses penelitian ini dilaksanakan dalam dua siklus masing-masing 4 kali pertemuan. Hasil penelitian menunjukkan peningkatan motivasi belajar siswa yang bermotivasi tinggi dari 16.67% dengan rerata capaian 43.99% dari indikator motivasi belajar pada observasi awal, meningkatan menjadi 33.33% dengan rerata capaian 46.40% pada pertengahan siklus I dan menjadi 61.11% dengan rerata capaian 69.62% pada akhir siklus I. Pada pertengahan siklus II siswa yang bermotivasi tinggi naik mencapai 80.56% dengan rerata capaian 75.09%, dan di akhir siklus II mencapai 91,67% dengan rerata capaian 80.99% dari indikator motivasi belajar siswa.   Kata Kunci : Motivasi Belajar, Metode Pembelajaran
PENERAPAN PERMAINAN TRADISIONAL ENGKLEK DALAM MENINGKATKAN KEMAMPUAN KOGNITIF ANAK USIA 5-6 TAHUN DI TK BINA GUNA
Authors: Desvarosa Eliya
Published: July 2023

Abstract: Application Of Hopscotch Traditional Games Improve Cognitive Ability In Children Aged 5-6 Years In Kindergarten Bina Guna. The aim of research to determine the increase cognitive abilities of children through play hopscotch grouped B1 TK Bina Guna Terrain Academic Year 2015/2016. The subjects were children in group B1 amounted to 16 children. The results of the first cycle analysis of 16 children in the classical there are 4 children (25%) had cognitive abilities develop according to expectations, and 12 children (75%) have the cognitive abilities begin to develop value is 49.60. The second cycle of 16 children 4 children (25%) have the cognitive ability developed very well, 9 children (56%) had cognitive abilities develop according to expectations, and as many as three children (19%) had cognitive abilities began to grow with the average value of the class ie 68.36. Keywords: Traditional Games hopscotch, Cognitive Ability   Abstrak : Penerapan Permainan Tradisional Engklek Dalam Meningkatkan Kemampuan Kognitif Anak Usia 5-6 Tahun Di TK Bina Guna. Tujuan penelitian untuk mengetahui peningkatan kemampuan kognitif anak melalui permainan engklek dikelompok B1 TK Bina Guna Medan Tahun Ajaran 2015/2016. Subjek penelitian adalah anak kelompok B1 berjumlah 16 anak. Hasil analisi siklus I dari 16 anak  secara klasikal terdapat 4 anak  (25%) memiliki kemampuan kognitif berkembang sesuai harapan, dan 12 anak (75%) memiliki kemampuan kognitif mulai berkembang dengan nilai yaitu 49,60. Siklus II dari 16 anak 4 anak  (25%) memiliki kemampuan kognitif berkembang sangat baik, 9 anak  (56%) memiliki kemampuan kognitif berkembang sesuai harapan, dan sebanyak 3 anak (19%) memiliki kemampuan kognitif mulai berkembang dengan nilai rata-rata kelas yaitu 68,36.   Kata Kunci : Permainan Tradisional Engklek,  Kemampuan Kognitif
Utilisation of Actiphage in combination with IS900 qPCR as a diagnostic tool for rapid determination of paratuberculosis infection status in small ruminant herds
Authors: Beinhauerova Monika , Slana Iva
Published: July 2023

Introduction

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of paratuberculosis, a chronic infectious intestinal disease occurring in domestic and wild ruminants. Early diagnosis of infected herds enabling timely adoption of control measures is tremendously important in view of the fact that the disease has a significant economic impact on farmers. The aim of this study was to evaluate the possibility of rapid detection of viable MAP on small ruminant farms based on environmental sample examination using a novel phage-based test named Actiphage.

Material and Methods

A total of 9 fresh and 28 frozen (8 or 11 years at -70°C) environmental samples originating from paratuberculosis-affected farms were analysed for the presence of MAP by four different diagnostic methods: Actiphage combined with real-time PCR targeting insertion sequence 900 (IS900 qPCR), conventional phage amplification assay, culture (frozen samples only), and direct ĪS900 qPCR.

Results

Viable MAP was detected in one fresh environmental sample using Actiphage–IS900 qPCR. None of the frozen samples tested positive using this diagnostic approach, which was consistent with the results of culture examination also providing information on viability.

Conclusion

This study describes other possible and innovative uses of phage-based methods in paratuberculosis control strategies. The Actiphage-qPCR was found to be less laborious than culture and provided results within six hours, suggesting that it may be a valuable tool for rapid initial determination of the infectious status of farmed animals based on environmental sample examination.
Numerical Analysis of Resistance Characteristics of a Novel High-Speed Quadramaran
Authors: Liu Xin , Yang Jinglei , Wu Defeng , Hou Liang , Li Xiaowen , Wan Qian
Published: July 2023

This paper utilised computational fluid dynamics (CFD) technology to calculate the resistance of a novel high-speed quadramaran in calm water using the Navier‒Stokes (N‒S) equation, analysed the total resistance, frictional resistance, and residual resistance characteristics of this novel high-speed quadramaran at different length Froude numbers, and compared them with the results of a conventional high-speed catamaran with the same displacement. The results showed that the total resistance of the quadramaran had a significant hump at the Froude number of 0.6, due to the complexity of the wave interference among the four demihulls, and the hump value was about 1.6 times that of the catamaran. Above the hump speed, the total resistance of the quadramaran decreased with the increase of the Froude number, until reaching the Froude number of 1.06, when the curve became flat, and it showed a maximum resistance reduction of 40% at the Froude number of 1.66 compared with the catamaran, where the total resistance curve was steep. The frictional resistance of the quadramaran increased gradually with the growth of the Froude number, which was basically consistent with the change trend of the catamaran. The residual resistance of the quadramaran first rose and then reduced with the rising Froude number, the curve showed a large hump due to the adverse wave interference, and the hump value was about 1.7 times that of the catamaran. Above the Froude number of 1.06, as the wave interference changed from adverse to favourable, the quadramaran had lower residual resistance than the catamaran. The bow and stern demihulls of the quadramaran were also analysed for their resistance characteristics. The total resistance of the bow demihulls increased gradually with the increase of the Froude number, the curve had a small hump at the Froude number of 0.7, and above the hump speed, the curve was steep. The total resistance of the stern demihulls first increased and then decreased with the growth of the Froude number, the hump value at the Froude number of 0.85 was significant and was about 2 times that of the bow demihulls, and the curve became flat above the Froude number of 1.51.
Image Processing Method for Cargo Container Identification in a Stack Within the Cargo Temperature Control and Fire Safety System on Container Ships
Authors: Konon Vladyslav
Published: July 2023

The current research is focused on the identification of cargo containers in a stack from their images in the infrared and visible spectra, in order to locate the container-origin of ignition within the cargo temperature control and fire safety system. The relevance of the topic is reinforced by the functional requirements for shipboard safety, which are embodied in Chapter II-2 of the Safety of Life at Sea (SOLAS) Convention, and demanded by the necessity of enhancing safety measures during cargo transportation by the world container fleet. The thermal imager’s field of view (FOV) and the coordinate dependencies between the object and its image have been studied and modelled, and an algorithm for fire detection has been defined within the scope of the current research in connection with the containers within the camera’s FOV. A corresponding verification has been carried out by means of simulation modelling using the Unity and C# programming language capabilities.
Understanding Fuel Saving and Clean Fuel Strategies Towards Green Maritime
Authors: Nguyen Van Nhanh , Rudzki Krzysztof , Dzida Marek , Pham Nguyen Dang Khoa , Pham Minh Tuan , Nguyen Phuoc Quy Phong , Xuan Phuong Nguyen
Published: July 2023

Due to recent emission-associated regulations imposed on marine fuel, ship owners have been forced to seek alternate fuels, in order to meet the new limits. The aim of achieving low-carbon shipping by the year 2050, has meant that alternative marine fuels, as well as various technological and operational initiatives, need to be taken into account. This article evaluates and examines recent clean fuels and novel clean technologies for vessels. The alternative fuels are classified as low-carbon fuels, carbon-free fuels, and carbon neutral fuels, based on their properties. Fuel properties, the status of technological development, and existing challenges are also summarised in this paper. Furthermore, researchers have also investigated energy-saving devices and discovered that zero-carbon and virtually zero-carbon clean fuels, together with clean production, might play an important part in shipping, despite the commercial impracticability of existing costs and infrastructure. More interestingly, the transition to marine fuel is known to be a lengthy process; thus, early consensus-building, as well as action-adoption, in the maritime community is critical for meeting the expectations and aims of sustainable marine transportation.
Employee Productivity: Exploring the Multidimensional Nature with Acculturation, Open Innovation, Social Media Networking and Employee Vitality in the Indian Banking Sector: An Analytical Approach
Authors: Kumari Savita , Jindal Priya , Mittal Amit
Published: July 2023

Purpose: The multi-dimensional nature of ‘employee productivity’ as a research construct needs extensive exploration, especially in view of the job-resources framework and in terms of stakeholder and accountability perspectives. The research study explored the topic with “individual” perceptions in exploring the pattern and tendency of the impact of acculturation and other organizational resources and protocols on the “perceived employee productivity”.
 
Theoretical framework: The theoretical implications of the research lie in the empirical exploration of the influences across employees, workplace-provided job resources, and contextual aspects that seem to shape the impetus for employee productivity.
 
Design/Methodology/Approach: The study delved into the aspects of ‘acculturation’, ‘open innovation’, ‘social media networking’, ‘employee vitality’, and ‘employee productivity’ for measuring the phenomenon in the Indian banking sector. The factors were operationalized with Likert scaling instruments and extractive factor analysis and structural equation modeling were leveraged.
 
Findings: The study observed a positive significant relationship among acculturation, open innovation, social media networking, employee vitality, and employee productivity in the Indian banking sector.
 
Research, Practical & Social implications: The research provides evidence that the organizational provision of job resources is a driving force behind the attainment of effective and sustainable employee productivity in the banking service sector. The research outcomes support and vindicate the prior research on the role of job resources in coping with workplace-derived uncertainties and exhibiting workplace productivity.
 
Originality/Value: The research outcomes illustrate the set of implications that possess meaning for core managerial application. The research has achieved the operationalization of employee productivity based on organizational support in the form of job resources.
PENGEMBANGAN MEDIA PUZZLE BERBASIS ANDROID PADA MATERI PETUNJUK PENGGUNAAN ALAT
Authors: Puspowati Dwi
Published: July 2023

The purpose of this study is to develop innovative, practical and effective learning media in Indonesian subjects with instructional materials for the use of tools. This research was motivated by the number of MI which did not have adequate learning media. This study uses the ADDIE development procedure with stages, Analysis, namely analyzing everything that includes needs and development, Design is making a framework, arrangement and appearance, Development includes the process of developing validation and revision media, Implementation is carried out in learning with media that has been developed and Evaluation, namely evaluating the media developed related to the level of effectiveness and attractiveness in learning. Data collection techniques used a questionnaire to assess the feasibility of the media and pretest and posttest questions to collect student value data. This research was conducted in class IV MI Qomarul Huda Banaran, Tembarak District, Temanggung Regency. The results of this study indicate that the Android-Based Puzzle learning media falls into the proper and effective category. This learning media was declared feasible based on the feasibility test according to media experts with a total percentage of 92% and valid material experts with a percentage of 81%. Whereas in its application, 32 students were able to increase the class average score from 68.33 to 86.7. So that the Android-based Picture Frame learning media is included in the valid, effective and feasible category to use.
PENGGUNAAN APLIKASI CLOUDX DAN QUIZZIZ UNTUK MENDUKUNG PEMBELAJARAN SEJARAH SECARA DARING
Authors: Marbun Tiarima
Published: July 2023

This remote classroom action research (CAR) was conducted to improve learning outcomes through CloudX, an application media. The subjects of this study were high school students, XII IPS-3 SMA Negeri 2 Tarakan. They are 33 students, consisting of 12 male students and 21 female students. It was  chosen since the students are solid and easy to cooperate. There are many problems in it, but the students are generally more responsive to the teacher. This classroom action research was conducted in two cycles with three teaching meetings in each. Both is designed to improve their learning outcomes using the CloudX. The results of the research prove that through the media can improve the students’ learning outcomes, as evidenced by the data in each aspect of observation. The action imlemented has been proved to have a good impact on the learning process. In the learning outcomes aspect, first cycle of meeting 1 showed 63.6% while in the second cycle of meeting 6 it increased to 90.9%% even though there were still 3 students or 9.1% had not achieved minimum completeness and 1 person was never present from the beginning research until the research is completed. Thus, the students who have not completed will be given remedial in a separate meeting in Google Classroom so as to achieve completeness in learning. Thus, learning using the CloudX has been proved to increase the student learning outcomes. It is recommended for teachers to use the CloudX Application in online learning.
Cooling and Heating a Greenhouse in Baghdad by a Solar Assisted Desiccant System
Authors: Joudi Khalid Ahmed , Hasan Mustafa Moayad
Published: July 2023

Modeling the microclimate of a greenhouse located in Baghdad under its weather conditions to calculate the heating and cooling loads by computer simulation. Solar collectors with a V-corrugated absorber plate and an auxiliary heat source were used as a heating system. A rotary silica gel desiccant dehumidifier, a sensible heat exchanger, and an evaporative cooler were added to the collectors to form an open-cycle solar assisted desiccant cooling system. A dynamic model was adopted to predict the inside air and the soil surface temperatures of the greenhouse. These temperatures are used to predict the greenhouse heating and cooling loads through an energy balance method which takes into account the soil heat gain. This is not included in conventional methods. The results showed satisfactory agreement with published papers. Also, the results of heating and cooling loads obtained revealed good agreement with those obtained from conventional methods when the soil heat gain is included. Two identical collectors in series of total area of 5.4m2 were employed as a heating system which provides an outlet air temperature of 30 o C at air mass flux of 0.06 kg/s.m2 at midday in January. While, a 65 oC outlet air temperature was achieved for the same mass flux at midday in August. The desiccant cooling system was operated in five operating modes; the ventilation mode and four recirculation modes with 20%, 50%, 70%,and 90% recirculation. The simulation results showed that a regeneration temperature of 60-70 o C is satisfactory for a cool supply air temperature of about 19.5 o C. Also, it was noted that 20-30 % recirculation of return air would result in suitable indoor greenhouse conditions for most periods of system operation. In addition, the coefficient of performance COP of the system was high compared with the conventional vapor compression systems.
Simultanous Electricity Production and Wastewater Ttreatment in a Microbial Fuel Cell Inoculeted with Anaerobic Sludge
Authors: Ismail Zainab Ziad , Jaeel Ali Jwied
Published: July 2023

In order to reduce the environmental pollution associated with the conventional energy sources and to achieve the increased global energy demand, alterative and renewable sustainable energy sources need to be developed. Microbial fuel cells (MFCs) represent a bio-electrochemical innovative technology for pollution control and a simultaneous sustainable energy production from biodegradable, reduced compounds. This study mainly considers the performance of continuous up flow dual-chambers MFC fueled with actual domestic wastewater and bio-catalyzed with anaerobic aged sludge obtained from an aged septic tank. The performance of MFCs was mainly evaluated in terms of COD reductions and electrical power output. Results revealed that the COD removal efficiency up to 89% was obtained for wastewaters having an average initial COD concentration of 350 mg/L. Stabilized power outputs were clearly observed achieving a maximum value of 170 mW/ m2.
Design and Implementation of a Multiplier free FPGA based OFDM Transmitter
Authors: Esttaifan Bashar Adel , AbdulLateef Oday , Mahmoud Waleed Ameen
Published: July 2023

Orthogonal Frequency Division Multiplexing (OFDM) is an efficient multi-carrier technique.The core operation in the OFDM systems is the FFT/IFFT unit that requires a large amount of hardware resources and processing delay. The developments in implementation techniques likes Field Programmable Gate Array (FPGA) technologies have made OFDM a feasible option. The goal of this paper is to design and implement an OFDM transmitter based on Altera FPGA using Quartus software. The proposed transmitter is carried out to simplify the Fourier transform calculation by using decoder instead of multipliers. After programming ALTERA DE2 FPGA kit with implemented project, several practical tests have been done starting from monitoring all the results of the implemented blocks (VHDL code) and compare them with corresponding results from simulation system implemented in matlab 2010a. The results of these practical tests show that the suggested approach gives a significant improvement in reducing complexity and processing delays (45 nsec) in comparison with the conventional implementations of OFDM transmitter.
PREDIKSI KOMPUTASI OBAT TRADISIONAL SULAWESI SELATAN Sauropus androgynus SEBAGAI BIOAKTIF SENYAWA ANTIOKSIDAN
Authors: Annisa Andi Bunga Sari
Published: July 2023

Sauropus androgynus adalah salah satu tanaman obat yang dapat ditemukan dengan mudah di daerah Sulawesi Selatan, tanaman ini telah banyak digunakan oleh masyarakat terutama bagikesehatan karena memiliki kandungan senyawa yang potensinya sangat besar dalam menyembuhkan berbagai jenis penyakit. Penelitian ini bertujuan untuk mengetahui senyawa dan potensi biaktivitasnya menggunakan pendekatan database melalui website http://kanaya.naist.jp/knapsack_jsp/top.html, http://way2drug.com/passonline/, http://classyfire.wishartlab.com/queries/new dan https://www.genome.jp/kegg/pathway.html. Hasil yang diperoleh dari penelitian ini yaitu terdapat 3 senyawa yang terkandung di dalam tanaman daun katuk yaitu Liriodendrin, Kaempferol 3-gentiobioside-7-rhamnoside dan Corchoionoside C yang termasuk dalam golongan senyawa flavonoid. Berdasarkan penyaringan potensi senyawa biaktivitas tanaman tersebut, ditemukan 22 potensi yang meliputi agenterapiteuk, antifilatiksin, antikanker, antikolestrol, antiinflamasi, antitumor, pelindung hati, antioksidan, antidiabetes, antivirus, detoksifikasi, antiinfeksi, antianemia, pelindung jantung, antiallergen, detoksifikasi racun, pencahar sembelit, antifungal, pemutih, antiradiasi, immunostimulant dan antidepresan. Oleh karena itu tanaman daun katuk (Sauropus andrgynus) memiliki potensi yang besar untuk dikembangkan di bidang Kesehatan berbasis kearifan local masyarakat Sulawesi Selatan.
Predicting the Past: Imputation of Historical Data
Authors: Spicer Rachel , Monroe M. Willis , Slingerland Edward , Muthukrishna Michael
Published: July 2023

Research using historical data is becoming more common across the social sciences. However, approaches using historical data suffer from a more acute missing data problem than approaches using contemporary data. Complete datasets are required to use many common statistical and machine learning techniques, the majority of which cannot handle missing data. One approach to handling missing data is to impute the missing values. Using the Database of Religious History (DRH), a large historical database, comprised of both quantitative and qualitative data, this research compares the accuracy and bias of 10 imputation methods. k-nearest neighbors (k-NN), missForest, Generalized low rank models (GLRM), Factorial analysis for mixed data (FAMD), DataWig, and five methods implemented in the R package mice (multiple imputation by chained equations). On average, a missForest approach had higher imputation accuracy and among the lowest bias compared to the other methods. The accuracy and bias of different methods implemented in mice were highly variable, highlighting the importance of researchers stating the precise method used for imputation, rather than general phrases such as ‘data were imputed using mice’.
Disease Modifying Therapies in Multiple Sclerosis: A Review
Authors: Raza Mohsin
Published: July 2023

Multiple Sclerosis is a  autoimmune demyelinating disease of the nervous system.This review paper evaluates disease modifying therapies for multiple sclerosis , a chronic autoimmune disease of the central nervous system. Over 20 Disease Modifying Therapies are available, categorized into injectables, oral agents, and infusions. The review covers their efficacy, safety, and tolerability. Established injectable Disease Modifying Therapies include interferon beta and glatiramer acetate, while newer oral agents like fingolimod offer conveniencewith more adverse effects. Infusions like natalizumab have higher efficacy but greater risks of adverse events. The paper also discusses newer Disease Modifying Therapies like cladribine. Treatment should be individualized based on patient characteristics, risk factors, and treatment goals. Overall, this review provides a comprehensive summary to aid clinicians in selecting appropriate Disease Modifying Therapies for Multiple Sclerosis.
The Impact of Profit and Cash Flow on Financial Distress Conditions in Hotel, Restaurant, and Tourism Sub-Sector Companies Listed on The Indonesia Stock Exchange
Authors: Nasution Umar Hamdan
Published: July 2023

This study aims to ascertain the effect that applying job expansion has on employee engagement. Purposive sampling was employed in the research at PT. Bank Aceh Syariah Medan Region, resulting in a sample size of 346 respondents. Multiple linear regression analysis is the method utilized for analysis. The findings indicated that employee engagement was impacted by employment expansion. The results of the t-test, which had a significance level of 0.000 but a lower threshold of 0.05 (0.000<0.05), clearly demonstrated this. Additionally, the results of the test for the coefficient of determination reveal that an increase in employee engagement has a 28% positive impact on job size, with the remaining 72% being influenced by other factors. A tough work expanding inspires sentiments of significance. High engagement results from self-meaning that develops as a result of task design that is in line with objectives and self-values. Additionally, work arrangements that encourage employees to create meaning in their work result in higher levels of engagement than those that downplay the significance of meaningful work in employees' lives.
RECOGNITION AND ENFORCEMENT OF INDONESIAN SHARIA ARBITRATION AWARDS IN FOREIGN COUNTRIES: CHALLENGES AND OPPORTUNITIES
Authors: Abdul Jamil  , Bin Shuaib Farid Sufian , Nur Heriyanto Dodik Setiawan
Published: July 2023

The Sharia Arbitration Board (Basyarnas) in Indonesia was formed to resolve disputes arising from agreements that are based on Islamic law. The existence of this body is essential in Indonesia, considering that the majority of the Indonesian Moslem community has begun to develop and utilize a Sharia-based economic system. During the current economic globalization, it is possible that foreign elements come into play in economic relationships. Thus, in the event of a dispute, the prevailing party must be able to use a Basyarnas arbitration award for enforcement and execution in the country where the losing party's assets are stored. By using a normative legal research method, this paper examines the efficacy of Basyarnas arbitration awards recognition and enforcement, particularly in countries with common law systems. Under the New York Convention on the Enforcement of Foreign Arbitral Awards, Basyarnas arbitration awards should not only be recognized and enforced in the court of the country of origin but also in jurisdictions where the losing parties’ assets located. This study concludes that Basyarnas arbitration awards should also be recognized and enforced in the countries with common law systems, because Sharia law is contrary to public policy in domestic law in the enforcing state. Hence, Basyarnas arbitration awards can be recognized in other countries if the award does not conflict with public policy in the enforcing state.
COVID-19 VACCINE HESITANCY IN MALAYSIA: CHALLENGES WITHIN THE LAW AND WAY FORWARD
Authors: Haron Hafidz Hakimi , Arsat Nadiah , Fauzi Muhammad Ashraf
Published: July 2023

For hundreds of years, vaccines have been a critical tool in the prevention of viral diseases. Vaccination programmes have gained prominence as one of the primary strategies for combating the COVID-19 pandemic. Despite this, COVID-19 vaccination programmes have frequently been viewed negatively by many. This is evident by the fact that vaccine hesitancy continues to grow at an unprecedented rate which is much facilitated by the rapid growth of communication and information technology. Despite the fact that vaccines and vaccinations are considered medical products, the difficulties they present are socio-legal in nature. The study examines four major factors that contribute to COVID-19 vaccine hesitancy in Malaysia namely compulsory vaccination and adverse event following vaccination (AEFI), information disclosure, misleading religious beliefs and sentiments, and misinformation and disinformation. It should be noted that, the identification and discussion of the factors mentioned above are vital as the failure of any future vaccination campaigns resulting from vaccine hesitancy would pose a huge threat to achieve the United Nations' Sustainable Goals (UNSDG), especially in respect of good health and sustainable economic growth. Therefore, for the purpose of this research, the paper adopts qualitative research approach to achieve its objectives. The paper recommends that the Malaysian vaccination legal framework be strengthened.
BALANCING THE RIGHT OF GIG ECONOMY WORKERS IN THE CONTEXT OF COLLECTIVE BARGAINING
Authors: Noor Shuhadawati Mohamad Amin
Published: July 2023

Collective bargaining forms an integral part of a trade union. In Malaysia, workers are protected under the relevant employment legislations that provide basic minimum rights. Although Malaysia’s freedom of association is embodied in the Federal Constitution, the rights of the gig economy workers, more often than not, are neglected. This is evident from the exclusion of this category of workers from the definition stated in the employment legislations. With this exclusion, gig economy workers are denied from establishing and joining a trade union. This subsequently unable them to have collective bargaining powers that resulted in the exploitation of their rights. The method adopted in this study is doctrinal in nature by analysing various employment related legislations and international conventions relating to trade union and collective bargaining and decided cases. It has been revealed that the weak definition of workmen impedes the right of workers in the gig economy to form a trade union. Based on the shortcoming identified, it is understood that the government plays a critical role in helping these workers to overcome barriers through strengthening the available legislations. This study proposed for gig economy workers to utilise other avenues currently available in other countries with the hope that collective agreement, non-binding agreement and application-based society exclusively for gig economy workers that could eventually lead to the forming of a trade union.
FIGHTING THE MENACE OF THE SOCIETY: PURSUING THE CORRUPTS
Authors: Nik Ahmad Kamal Nik Mahmood
Published: July 2023

In 2021, Transparency International ranked Malaysia 62 out of 180 countries in the world, and the perceived level of corruption in the public sector was recorded at 63.30% as compared to 17.06% in the private sector. Historically, the effort to prevent corruption in Malaysia began in 1950 with the introduction of the Prevention of Corruption Ordinance (POCO) 1950 to replace the previous laws of the Federated Malays States (Enactment No. 23 of 1938), the State of Johore (Johore Enactment No. 14 of 1940) and the former Straits Settlements (Straits Settlements Ordinance No. 14 of 1937). Applying doctrinal research and adopting a historical and descriptive approach, the paper seeks to describe the history of the anti-corruption law and agencies created before and after independence focusing on the agencies’ organisational and structural development. There is also a brief discussion on the late Tan Sri Harun Mahmud Hashim who helmed the anti-corruption agency. Since independence, the government had tirelessly carried out efforts to combat corruption with the formation of the Criminal Investigation Department (Special Crime) and the Anti-Corruption Section (ACS) and then consolidated into one body called the Anti-Corruption Agency (ACA) with the passing of the Anti-Corruption Agency Act 1982. In 2008, the government unanimously approved the establishment of the Malaysian Anti-Corruption Commission (MACC) by replacing the ACA Act 1997 with the Malaysia Anti-Corruption Commission Act 2009, which came into effect on 1 January 2009. The MACC became an independent, transparent, and professional body to effectively and efficiently manage the nation’s anti-corruption initiatives
THE LIFE OF TAN SRI HARUN M. HASHIM: A MEMOIR
Authors: Najibah Md Zin  , Khadijah Mohd Najid
Published: July 2023

This article will provide an insight into the colourful journey of Tan Sri Harun Hashim – his life experience, education background, his distinguished career path and achievements as well as contributions made especially to the education sector and the legal profession. It is also an attempt to provide a glimpse of the other side of Tan Sri Harun Hashim, off the limelight – as a father, a grandfather, a mentor and a friend, as he left his footprints firmly etched in the memory of his loved ones. This research employs a qualitative method focusing on in-depth interviews as well as a comprehensive analysis of relevant books, articles, newspaper reports and documentations. In this article, fragments from the colourful journey of Tan Sri Harun Hashim come from stories narrated through interviews with those who were close to him and had personal encounters with Tan Sri while some other information is extracted from his well-known column, “The Benchmark”, appearing in the New Straits Times from 1994 until his demise in 2003. “The Benchmark” provided useful insights into the ideals and aspirations of Tan Sri, and relayed some first-hand information on his life journey and extraordinary experiences. Some information on Tan Sri’s personal life is gathered from exclusive interviews with Tan Sri’s family members themselves, conducted by the authors and Hisham Harun, Tan Sri Harun’s son. This article aims at offering a unique biography of Tan Sri Harun Hashim who was known to be a gem to the nation, especially in the legal and education sectors in Malaysia. It is an effort to highlight and set in stone the legacy left by him so that it becomes a benchmark for the younger generations to follow and emulate.
Characteristics of the use of digital twins by industrial enterprises: the experience of foreign countries and Kazakhstan
Authors: Tashenova L.V. , Babkin A.V. , Mamrayeva D.G. , Kulzhambekova B.Sh.
Published: July 2023

Object: digital twins, adapted to the tasks of industrial companies.

Methods: content analysis for the purpose of organizing and structuring the main scientific research related to the study of the use of digital twins, their role and importance for industrial companies; the analysis method that allowed to evaluate the current state of digitalization of production processes in companies; a graphic interpretation method that allowed to visualize the obtained results.

Findings: the concept of “digital twin” is considered and the aspects of its application in the sphere of industrial production are analyzed on the example of foreign companies and enterprises of Kazakhstan; the tasks of digital twins and the advantages of their implementation in production are pointed out; the stages of building digital twins were studied.

 Conclusions: the study showed that the use of digital twins opens up new opportunities to improve the efficiency and competitiveness of an industrial company. The results provided an opportunity to assess the annually growing interest in the technology of digital twin; based on the analyzed sources, successful examples of the implementation of digital twins in the activities of industrial enterprises of foreign countries and Kazakhstan are considered.
Analysis of the experience of managing the development of giftedness in the education system
Authors: Karkulova А.А. , Satanov A.B. , Zhumageldi N.M. , Shakeyev S.S.
Published: July 2023

Object: Based on the analysis of managerial experience in the development of giftedness in the education system of foreign countries, the article describes the models for the development of the education of gifted children adopted in the developed countries of the world. A working understanding of giftedness is defined at the present stage of the practice of implementing the education of the gifted in the conditions of Kazakhstani practice in the context of a specialized education system for gifted children. The possibility of using adapted organizational conditions for the development of specialized educational institutions for gifted children is substantiated.

Methods: Theoretical analysis of foreign research materials on the problem of the development of education for gifted children, analysis of the legislative framework of the Republic of Kazakhstan on the research problem.

Findings: The analysis of theoretical materials made it possible to identify the presence of problem areas – the lack of a unified understanding of giftedness in science, which led to the existence in practice of a large number of educational models for the development of gifted children in the developed countries of the world. The grounds for understanding giftedness in Kazakh science are revealed. We believe that the definition of giftedness should have a functional characteristic, which allows using an activity approach in working out a model for the development of the education of gifted children, as well as taking into account the direction of development of the activities of gifted people, focused on the tasks set for the development of state programs.

Conclusions: An analysis of models for the effective development of the education of gifted children, implemented in the developed countries of the world, is presented. We believe it is possible to develop an adaptive development model of the Kazakh model for the development of education for gifted children.
OPTIMAL CONTROL OF AN AUTONOMOUS LIME SOLUTION DISPENSER TO WHEAT STRAW WHEN MANUFACTURED ON MOBILE COMBINED PELLETS FOR BIOGAS PLANTS
Authors: Shvorov S. , Polischuk V. , Miroshnyk V. , Opryshko O. , Tsygulyov I. , Davidenko T.
Published: July 2023

The object of the study is the drive electric motor of the autonomous lime solution dispenser for wheat straw when making pellets for biogas plants. The purpose of the work is to determine the optimal control law of the drive electric motor of the autonomous dispenser of lime solution to wheat straw when pellets for biogas plants are produced on mobile harvesters. To achieve the goal, the following tasks were solved: the substantiation of the pellet production technology for biogas plants using mobile harvesters was carried out; a model of functioning of the drive electric motor of an autonomous dispenser of lime solution for wheat straw was developed. With the help of the proposed model, it is possible to determine the optimal control modes of the drive electric motor of the autonomous lime solution dispenser for wheat straw with minimal power consumption for heat losses and for overcoming viscous friction in the lime solution dosing process. The most important result of the research is the substantiation of the pellet production technology using the self-propelled Metitron 560 combine harvester using a special lime solution dispenser for extruded straw, which ensures the highest rate of methane release. The significance of the research results is that the use of pellets of extruded straw and lime allows to increase the rate of methane release by more than 60% compared to the fermentation of untreated straw. It is advisable to use an autonomous energy-efficient dispenser on the Metitron 560 harvester, which is capable of producing pellets of 6 to 12 mm in size from straw of various crops directly in the field with the addition of lime solution to increase biogas output. The advantage of using pellets from extruded wheat straw is also that such raw materials are better transported and stored in warehouses, which is necessary for the continuous operation of biogas plants, since agricultural waste is seasonal.