bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of oral bioavailability of nanocapsules loaded-curcumin in-vivo
Authors: Ananda  , Nabeela Tariq  , Nosheen Rafiq  , Shahzad Yousaf  , Shabbar Abbas
Published: February 2021

Curcumin, a hydrophobic polyphenol found in rhizome of turmeric (curcuma longa) is one of the generally used spice in Asian countries. It has been found through studies that it has numerous health promoting properties and is proved to have curative properties as it possesses antioxidant and anti-inflammatory properties. Due to low oral bioavailability, decreased solubility, quick metabolism and removal from body, it is challenging to achieve maximum benefits from it. This study was aimed to enhance curcumin oral bioavailability by making use of nanoencapsulation technique. Biodegradable nanocapsules were prepared by consecutive addition of food grade polyelectrolytes including OSA-modified starch (PGU), as an emulsifier, chitosan and sodium-carboxymethylcellulose by ultrasonication technique using primary nanoemulsion as template. Results showed that the mean droplet diameter of nanocapsules was 160.57 ± 1.06 nm, the average PDI was 0.14 ± 0.01 and average charge was recorded as -24.43 ± 0.49 mV. Microscopy results showed that the nanostructures were spherical in shape having mean droplet diameter below 200nm. The nanocapsules assessment as a carrier in enhancing the in vivo oral bioavailability of curcumin was made; however, further studies and better tools are needed to clearly know the potential of developed nanosystem.
Effect of thymalin on adaptive immunity in complex therapy for patients with COVID-19
Authors: Khavinson V. Kh. , Kuznik B. I. , Volchkov V. A. , Rukavishnikova S. A. , Titova O. N. , Akhmedov T. A. , Trofimova S. V. , Ryzhak G. A. , Potyomkin V. V. , Saginbaev U. R.
Published: February 2021

Results of comparative assessment of level of antibodies of IgG to SARS-CoV-2 in dynamics at standard and complex methods of treatment with use of medicinal peptide medicine of a timus of a timalin for patients with COVID-19 are presented in article. It was found that as a result of standard treatment, patients showed a decrease in antibody levels by 53% after 104 days. The addition of thymalin to standard therapy slowed down the decline of this indicator. So, a similar indicator in patients who took thymalin was only 21%. This contributed to maintaining strained adaptive immunity. The detected immunomodulatory properties of the preparation of thymalin with respect to COVID-19 can be reflected both in the formation of an effective immune layer of the population through natural immunization, and in the process of antibody formation during vaccination of target contingents.
Pulmonary embolism: old problem, new approaches to treatment
Authors: Tyurin V. P. , Pronin A. G.
Published: February 2021

There is no indication when to perform thrombolytic or anticoagulant therapy in patients with moderate-high risk of early death in accordance with the stratification of the European society of cardiology. The purpose of the study: to establish clinical, laboratory, and instrumental criteria for the choice of therapy volume optimization in patients with moderate-high risk of early death. Material and methods. The study included 154 patients with pulmonary embolism (PE) of high, moderate-high, moderate-low risk of death. An analysis was performed to determine the most significant indications for thrombolytic therapy in PE. Results. The presence of established «undoubted» criteria indicates the need for thrombolytic therapy. These include an increase in the size of the right ventricle compared to the left, paradoxical movement of the interventricular septum, hypokinesia of the right ventricle on еchocardiography. «Questionable» criteria were also identified: more than 50 mm Hg increased pulmonary artery pressure, more than 20 mm dilation of the inferior Vena cava, more than 3 cm dilatation of the right ventricle on еchocardiography, deep SIQIII on ECG, syncopal states in the anamnesis, increased NT-proBNP values, less than 90% arterial blood saturation. Thrombolytic therapy is indicated for patients with a combination of 2 or more of these criteria, in other cases anticoagulant therapy is prescribed. Conclusion. The use of established criteria makes it possible to differentiate treatment of patients with moderate-high risk of early death and reduce the likelihood of developing chronic post-thromboembolic pulmonary hypertension by 2.9 times.
Military-field therapy issues in the clinical medicine journal (to the 100th anniversary of the journal foundation)
Authors: Simonenko V. B. , Knopov M. Sh. , Taranukha V. K.
Published: February 2021

The article presents materials on military-field therapy for the entire period of the journal publication (1920–2020). Over the past years the journal published about 240 scientific articles on various problems of military-field therapy: 20 — on organizational issues, more than 120 — on clinical problems , about 50 — jubilee and historical articles, and more than 50 — dedicated to personalities.
History of military radiology (to the 90th anniversary of the department of radiology and radiology with the course of ultrasound diagnostics of the Military Medical Academy)
Authors: Zheleznyak I. S. , Trufanov G. E. , Ataev A. G.
Published: February 2021

The Department of radiology and radiology with the course of ultrasound diagnostics of the Military Medical Academy celebrated its 90th anniversary. The Military Medical Academy was the first medical institution in Russia, which immediately after the discovery of x-rays formed the main directions of development of the discipline: research in the field of radiation physics, clinical direction and military radiology, as well as educational and methodological work. The basics of radiology were taught to 5th-year students at the Academy as early as 1897, two years after the discovery of x-rays by V. K. Roentgen. Since 1914, the first courses of military x-ray technicians were organized at the Academy, and in 1923 an independent course of radiology was introduced and the teaching of a new discipline was given a clinical orientation. Glorious traditions were formed at the Department solely due to a remarkable galaxy of scientists who worked within its walls and were at the origins of Russian clinical radiology. These are Professor Mikhail Isaevich Nemenov, academician of the AMN, Professor Georgy Artemyevich Zedgenidze, Professor Leonid Davidovich Lindenbraten, corresponding member of the AMN, Professor Albert Nikolaevich Kishkovsky and many other bright names. Over the years, the Department of radiology of the Academy became recognised as a major educational and scientific center for training and improvement of highly qualified professionals, not only medical institutions of the Ministry of defense of Russia, but also the health of the country. Currently, the staff of the Department is on the rise, carrying out high-level research activities and a complex of everyday radiation studies for the needs of the Academy’s clinics, medical institutions in St. Petersburg and the North-West region.
Patients’ Perspectives On Ideal Physician Behaviors
Authors: Bendapudi Neeli M. , Berry Leonard L. , Frey Keith A. , Parish Janet Turner , Rayburn William L.
Published: February 2021

We incorporated the views of patients to develop a comprehensive set of ideal physician behaviors. Telephone interviews were conducted in 2001 and 2002 with a random sample of 192 patients who were seen in 14 different medical specialties of Mayo Clinic in Scottsdale, Ariz., and Mayo Clinic in Rochester, Minn. Interviews focused on the physician-patient relationship and lasted between 20 and 50 minutes. Patients were asked to describe their best and worst experiences with a physician in the Mayo Clinic system and to give specifics of the encounter. The interviewers independently generated and validated seven ideal behavioral themes that emerged from the interview transcripts. The ideal physician is confident, empathetic, humane, personal, forthright, respectful and thorough. Ways that physicians can incorporate clues to the seven ideal physician behaviors to create positive relationships with patients are suggested.
RETHINKING THE ROLE OF KIAI LEADERSHIP IN MODERNIZING PESANTREN IN CIANJUR, WEST JAVA
Authors: Hasyim Abdul Wahid
Published: February 2021

Abstract: This article seeks the role of the Kiai in the modernization of pesantren in Cianjur, West Java. Taking the cases of Pesantren al-Musyarrofah, Pesantren Darul Falah, Pesantren as-Syuja’i, and Pesantren Darussuada al-Amin, this research uses qualitative methods. The study found that although these Pesantrens played a significant role in da’wah, education, and the development of socio-religious institutions in Cianjur, their existence of experienced ups and downs due to the management system practiced by the pesantren leadership. In addition, it was also implied that modern management combined with the Kiai charisma has become a success factor in the modernization of the pesantren.

Abstrak: Artikel ini berupaya mengkaji peran kiai dalam modernisasi pesantren di Cianjur, Jawa Barat. Dengan memokuskan pada kasus Pesantren al-Musyarrofah, Pesantren Darul Falah, Pesantren as-Syuja’i dan Pesantren Darussuada al-Amin, penelitian ini menggunakan metode kualitatif. Berdasarkan penelitian yang dilakukan ditemukan fakta bahwa meskipun berperan besar dalam bidang dakwah, pendidikan, dan pengembangan pranata sosial keagamaan di Cianjur, keberadaan keempat pesantren mengalami pasang surut yang disebabkan oleh sistem manajemen yang dipraktikan oleh pimpinan pesantren. Penelitian ini juga mengimplikasikan bahwa manajemen modern yang dipadukan dengan kharisma Kiai menjadi faktor keberhasilan modernisasi pesantren.

Keywords: Islamic education, pesantren, kiai, management, leadership
Perancangan Sistem Informasi Pengolahan Data Penjualan Secara Kredit dan Controlling Stock Dengan Menerapkan Metode Backorder Pada Toko Master Menggunakan Bahasa Pemrograman Java dan Database MySql
Authors: Prayoga J.
Published: February 2021

Had done the research on the Master Store, where the problems are used as the basis in writing this is a system of data processing sales on credit and controlling stock. Through the process of direct observation of the field has gained the weaknesses of the existing system. Although not entirely but more directed to a specific problem, it is expected to contribute significantly to the users of the system. The author designed the information system of data processing sales on credit and controlling stock based on Java Master Store, because with this information system will be faster, precise, and accurate. In designing this new system used the Java programming language and MySQL database, with the design of this new system the authors embody the system of data processing sales on credit and efficient controlling stock on the Master Store.

 

Keywords: Credit Sales Data Processing And Controlling Stock, JAVA, MySQL
PENGEMBANGAN PRODUKSI VCO (VIRGIN COCONOUT OIL) UNTUK INDUSTRI RUMAH TANGGA MELALUI SENTUHAN TTG (TEKNOLOGI TEPAT GUNA) DI DESA TONTULOW, KECAMATAN PINOGALUMAN, KABUPATEN. BOLAANG MONGONDOW UTARA, SULAWESI UTARA
Authors: Djamalu Yunita , Antu Evi Sunarti , Kurniawan Max , Harun Dayuwanto
Published: February 2021

Vco (Virgin Coconout Oil) merupakan minyak kelapa yang diolah secara tradisional oleh masyarakat didesa-desa yang mempunyai aroma dan rasa yang khas dan banyak digemari masyarakat Gorontalo. Tujuan jangka panjang program ini yakni mengembangkan produksi VCO (Virgin coconout oil) dalam skala industry rumah tangga dengan menggunakan alat teknologi tepat guna. Target khusus yang ingin dicapai yakni menjadikan desa Tontulowsebagai desa pusat produksi VCO di Gorontalo. Sasaran dari program yakni masyarakat penghasil VCO dalam skala kecil yang ada di desa Tontulow Kec. Botupingge Kab. Bone Bolango. Hal ini dipertimbangkan karena lokasi desa Tontulowbanyak ditumbuhi pohon kelapa dan ada beberapa kelompok masyarakat desa Tontulowpenghasil VCO yang belum lancar dan stabil dalam memproduksi virgin coconout oil. Metode yang digunakan dalam program ini adalah pelatihan penggunaan alat Teknologi tepat guna dalam pengolahan VCO dalam skala industri rumah tangga. Untuk mendukung metode tersebut maka alur kegiatannya meliputi perancangan alat, pembuatan/fabrikasi alat, uji coba alat, serta memberikan pelatihan.
Impelementasi Gamifikasi Pada Web STMIK PPKIA Pradnya Paramita
Authors: Arifin Samsul , Widarti Dinny Wahyu
Published: February 2021

Dalam menerbitkan Surat Keterangan pendamping Ijazah (SKPI) di Kampus STMIK PPKIA Pradnya Paramita, dibutuhkan data yang akurat dari mahasiswa, namun mahasiswa seringkali mengumpulkan diakhir masa kuliah mereka (menjelang lulus). Hal ini menyebabkan sekretaris Program Studi menjadi kewalahan. STMIK PPKIA Pradnya Paramita sudah memiliki aplikasi portal mahasiswa yang berfungsi untuk proses KRS, KHS, Jadwal Kuliah, Biodata Mahasiswa dan SKPI. Penggunaan aplikasi portal ini berjalan dengan baik, kecuali bagian SKPI. Didapat data bahwa 100% mahasiswa tidak ada yang mengisi formular SKPI semasa mereka kuliah. Mahasiswa mengisi hanya ketika menjadi syarat penerbitan ijazah. Untuk meningkatkan partisipasi mahasiswa dan ketersediaan data dalam penerbitan SKPI, maka diusulkan pengembangan aplikasi portal mahasiswa yang dapat menarik mahasiswa untuk mengisi data SKPI. Kesukaan orang untuk bermain aplikasi permainan mendorong pengembang aplikasi menerapkan fitur layaknya game dalam aplikasi merekam. Untuk itu perlu ditambahkan fitur seperti poin, level, badges, leaderboard seperti layaknya aplikasi permainan. Pengembangan aplikasi portal mahasiswa ini menggunakan SDCL dengan metode waterfall. Aplikasi yang sudah ada dikembangkan dengan menambah fitur gamifikasi dengan tujuan meningkatkan partisipasi mahasiswa dalam menggunakan aplikasi portal, khususnya untuk melengkapi dan memperbarui prestasi dan keterampilan yang sudah dikuasai.
Desain Aplikasi Pengadaan Benih Ikan Di Balai Benih Ikan Kabupaten Morowali Berbasis Android
Authors: Gobel Citra Yustitya , Santawal Santawal , Mayang Dewi Cahyani
Published: February 2021

Balai Benih Ikan (BBI) Korowalelo saat ini memiliki 14 Fasilitas kolam yang terdiri dari 6 Kolam Pematangan, 2 Bak Pemijahan, 4 Kolam Larva dan 2 Kolam Pendederan. Benih ikan yang telah dihasilkan akan dijual secara umum. Namun Informasi Pengadaan Benih Ikan di Balai Benih Ikan Kabupaten Morowali Utara ini masih kurang diketahui oleh masyarakat umum karena lokasi Balai yang berada didalam wilayah perumahan warga dan sistem penyebaran informasi Balai Benih Ikan yaitu bertanya kepada orang lain. Sehingga penulis merancang sebuah aplikasi berbasis android yang dapat memudahkan penyajian informasi kepada masyarakat umum serta mempermudah pemesanan benih ikan.Metode analisis sistem yang digunakan adalah metode waterfall dengan tahapan yaitu perancangan sistem (system engineering), interaksi intensif antar analis sistem (Requirement Analysis), desain (Design), pengkodingan (Coding), eksekusi program (Testing), pemeliharaan (Maintenance).Untuk menguji apakah aplikasi dapat berjalan dengan baik maka dilakukan pengujian white box dan black box dan dapat disimpulkan bahwa hasil perhitungan Cyclematic Complexcity (CC) sama dengan V (G) karena itu dapat disimpulkan bahwa sistem dapat berjalan secara efektif dan efisien.Implementasi sistem diterapkan pada android versi 7.0 (Nougat), versi 8.0 (Oreo), dan Versi 6.0 (Marshmallow
Perhitungan Matematis Algoritma C4.5 Untuk Memprediksi Penjualan Wallpaper (Studi Kasus : Toko Ali Banyuanyar Probolinggo)
Authors: Nurhidayati Nurhidayati , Marzuki Imam
Published: February 2021

Mewarnai dinding rumah dengan wallpaper memang bisa menambah kesan indah pada suatu ruangan, sehingga ruangan terlihat lebih ekspresif. Bermacam motif, warna, dan corak wallpaper dapat dipilih. Untuk meningkatkan penjualan wallpaper, Penjual harus lebih cermat menyediakan wallpaper mana yang akan banyak peminatnya. Perlu perekomendasian  jenis jenis wallpaper. Data yang diperlukan yaitu data merk wallpaper terbaik, warna, motif, kualitas bahan, ukuran, dan harga. Kemudian data tersebut diklasifikasikan. Metode yang digunakan untuk klasifikasi adalah data mining dengan algoritma C4.5. Dari proses perhitungan algoritma C4.5 akan didapatkan beberapa rule. Rule tersebut dijadikan dasar untuk memprediksi penjualan wallpaper.
Digital signal processing-based approach to identify splicing mutations for detecting genetic diseases
Authors:   Indian Institute of Information Technology Allahabad, Devghat, Jhalwa, Prayagraj-211015, U. P. India, Varadwaj Pritish Kumar , Purohit Neetesh ,   Indian Institute of Information Technology Allahabad, Devghat, Jhalwa, Prayagraj-211015, U. P. India, Lahiri Tapobrata ,   Indian Institute of Information Technology Allahabad, Devghat, Jhalwa, Prayagraj-211015, U. P. India, Antisiperov V.E. ,   Indian Institute of Information Technology Allahabad, Devghat, Jhalwa, Prayagraj-211015, U. P. India
Published: February 2021

More than ninety percent of genes in Homo Sapience are reported to exist as discontinuous segments of coding regions called as ‘Exons’ and are separated by intervening non-coding regions, called “Introns”. During the splicing mechanism, the non-coding regions got removed and coding regions are joined together for producing the precursor messenger RNA. The site of these Exon-Intron splicing is called Splice Site. The anomalies caused due to genetic mutation in spice site during the processing of precursor m-RNA into mature m-RNA causes several genetic diseases like Cancer, Dementia, Epilepsy, Hematological Disorders, Parathyroid Deficiency etc. It is estimated that as many as 50% of disease-causing mutations affect splicing. The present invention describes the design of digital signal processing-based approach to detect these Splicing Site. A successful identification of the splice site will help in finding the mutations hence can be used as an inference tool for predicting genetic disease.
Римма и Леонид Браиловские
Authors: Шаханова Антонина
Published: February 2021

Творчество четы художников Браиловских известно лишь относительно узкому кругу исследователей и ценителей искусства, несмотря на то, что их деятельность в области живописи, графики, архитектуры, декоративно-прикладного искусства и мемориальной скульптуры, в театрально-декоративной, археологической, выставочной и общественной работе начала ХХ века заслуживает пристального внимания. Статья раскрывает некоторые страницы их насыщенной событиями жизни.
MARGARET’S EMOTIONAL AND SOCIAL LONELINESS IN TENNESSEE WILLIAM’S “A CAT ON THE HOT TIN ROOF”
Authors: Husien Saddam
Published: February 2021

This study concentrates to analyze Margaret’s character about loneliness that experience by her in Tennessee William’s a Cat on the Hot Tin Roof. Loneliness is unpleasant situation that experience by someone when the one’s desire or ambition is not equivalent in social relationship. Furthermore, the source of the data is telling about someone who experiences loneliness which contains the type of loneliness, effect of loneliness and the effort to overcome from loneliness, consequently the theory of loneliness is chosen. Besides that, this study is qualitative design because the data are collected in the form of words. The data of this study are narrator’s explanations and the character’s utterances related to the loneliness experienced by Margaret and the writer has function as the key instrument in this research. According to the analysis of the drama, the writer has finds the answer of the research problem, that are types and effect of Margaret’s loneliness and Margaret’s effort to overcome or coping loneliness in Tennessee William a Cat on the Hot Tin Roof. There are two types of Margaret’s loneliness, they are emotional and social loneliness. Firstly, Margaret’s emotional loneliness is her unsatisfactory relation with Brick. She does not get intimate relation from Brick. Therefore, she cannot get unpleasant situation from Brick. Secondly, Margaret’s social loneliness, she as a part of Brick’s family is not respected and accepted in the family due to her childless and Brick’s addiction to liquor. Effects of Margaret’s loneliness. She transforms to be rude and frantic, she becomes talkative person, and the last effect is she has much power to be brave person. Margaret’s effort to overcome her loneliness, she tries to understand Brick’s situation and attitude to get attention and more communication with him.
LARANGAN LGBT MENJADI APARATUR SIPIL NEGARA DI KEJAKSAAN AGUNG
Authors: Zulfi Danang Ardiansyah
Published: February 2021

AbstractTheppurpose ofpthis research ispto providepa solution to the letter Number: Peng-01 / C / Cp.2 / 11/2019 which contradicts the constitution (1945 Constitution) and Law 39/1999 concerning Human Rights. Usingpnormative researchpwith anporientation thatpis not conceptual.pThrough thispresearch, the researcherpoffers the regulations that must be made based on the 1945 constitution. At the time of the election of candidates for civil servants in 2019, there are opening positions for prison guards and prisoner drivers, the announcement is contained in Letter Number: Peng- 01/C/Cp.2/11/2019 in the specific requirements of paragraph (2) applicants may not have sexual orientation disorders and transgender decisions from the attorney general must be revoked because they violate the constitution and Law 39 of 1999 concerning Human Rights, the Attorney General's Office should make a selection based on ability (competence) candidates for civil servants are not based on sexual orientation and transgender disabilities.Keywords: human rights; LGBT; The 1945 Constitution, AbstrakTujuan penelitian ini adalah untuk memberi solusi dari SuratPNomor: Peng-p01/C/Cp.2/11/2019 yang bertentanganPdengan konstitusi (Undang-UndangpDasarp1945) danpUndang-Undang 39 Tahunp1999 tentangpHak AsasipManusia. Menggunakanppenelitian normatifpdengan orientasi yangptidak bersumber kepadapkonseptual. Melaluippenelitian ini peneliti menawarkan peraturan yang dibuat harus berdasarkan konstitusi Undang-Undang Dasar 1945. Pada saat pemilihan calon pegawai negeri sipil tahun 2019 membuka lowongan pengawal tahanan dan supir tahanan, pengumuman tertuang pada surat SuratpNomor: Peng-p01/C/Cp.2/11/2019 pada persyaratan khusus ayat (2) pelamar tidak boleh mempunyai kelainan orientasi seksual dan transgender keputusan dari kejaksaan agung ini harus di cabut karena melanggar konstitusi dan Undang-Undang 39 tahun 1999 tentang Hak Asasi Manusia seharusnya Kejaksaan Agung melakukan seleksi berdasarkan kemampuan (kompetensi) calon pegawai negeri sipil tidak berdasarkan Kelainan orientasi seksual dan Transgender.
PENGGUNAAN CAIRAN ROKOK ELEKTRIK NON TEMBAKAU PADA KAWASAN TANPA ROKOK DI SURABAYA
Authors: Arzaqi Zam
Published: February 2021

AbstractThis study aims to analyze the use of non-tobacco e-cigarette liquids in non-smoking areas in Surabaya. The type of research used is empirical research. The data analysis technique used in this study is verbatim analysis. Verbatim is the writing (text) of words, sentences, or conversations from audio / video recordings. - qualitative analysis techniques. Based on the results of the research that has been done, it can be explained that the presence of e-cigarettes creates controversy where various parties consider that e-cigarettes provide a lower risk than conventional cigarettes so that they are safe to use and consider that local regulations related to KTR in Surabaya are not appropriate because they equate non-liquid e-cigarettes. tobacco with tobacco products. However, after investigating several studies, it was found that although some electric liquid products claim to be nicotine-free, nicotine content is still found in them, although not as much as nicotine liquid products. So based on this, it can be concluded that non-tobacco e-liquid is included in Perda Surabaya No. 2-2019 so that it is prohibited to use it in areas without smoking.Keywords: e-cigarette; e-liquid non tobacco; No Smoking AreaAbstrakPenelitian ini bertujuan untuk menganalisis penggunaan cairan rokok elektrik non tembakau pada kawasan tanpa rokok di Surabaya. Adapun jenis penelitian yang digunakan ialah penelitian empiris. Adapun teknik analisis data yang digunakan pada penelitian ini adalah analisis verbatim. Verbatim adalah penulisan (teks) kata-kata, kalimat, ataupun percakapan dari rekaman berupa audio/video. -teknik analisis kualitatif. Berdasarkan hasil penelitian yang telah dilakukan dapat dijelaskan bahwa kehadiran rokok elektrik menimbulkan kontroversi dimana berbagai pihak menilai bahwa rokok elektrik memberikan resiko yang lebih rendah dibandingkan rokok konvensional sehingga aman digunakan dan menilai bahwa peraturan daerah terkait KTR di Surabaya tidak tepat karena menyamakan cairan rokok elektrik yang non tembakau dengan produk tembakau. Namun setelah dilakukan penelusuran beberapa penelitian menunjukkan bahwa meskipun beberapa produk cairan elektrik mengklaim bebas nikotin namun tetap ditemukan kandungan nikotin di dalamnya meskipun tidak sebanyak produk liquid nikotin. Sehingga berdasarkan hal ini maka dapat disimpulkan bahwa cairan rokok elektrik (e-liquid) non tembakau termasuk di dalam Perda Surabaya No. 2-2019 sehingga dilarang di gunakan pada kawasan tanpa rokok.
Technology of polymer and composite materials
Authors:   V.P. Larionov Institute of Physical-Technical Problems of North, RAS, Siberian Branch, Lukachevskaya I.G. , Lebedev M.P. ,   Federal Research Centre «Yakutsk Scientific Centre, SB, RAS», Struchkov N.F. ,   V.P. Larionov Institute of Physical-Technical Problems of North, RAS, Siberian Branch
Published: February 2021

The influence of climatic factors on properties of basalt and fiberglass made by the infusion method has been studied by sequential laying some reinforcing material on the mold, impregnating with a three-component epoxy binder, consisting of ED-22, Iso-MTHFA, Agidol 53, and curing at a temperature of 160±2 °С, within 4 hours. Full-scale climatic tests of basalt fiber and fiberglass in a very cold climate zone demonstrated their resistance to climatic influences, which is confirmed by a high level of preservation of their strength parameters. Exposure of basalt fiber to natural conditions led to a decrease in tensile strength by 14% and an increase in flexural strength by 18%. The values of fiberglass increased by 9% (ultimate tensile strength) and 22% (ultimate tensile strength). Porosity measurements showed that after exposure, basalt-textolite samples increased open porosity by 62%, while glass-textolite samples decreased by 39%. After climatic tests, an increase in the average range of the inhomogeneities (Ra) of the surface of the basalt-textolite up to 0.48 μm (initial — 0.70 μm, after exposure — 1.18 μm). In fiberglass, the average roughness increases by 4 times after exposure (initial — 1.03 μm, after exposure — 4.08 μm).
Social Media Tools Accentuating Self-directed Personal Learning Trajectories: Underpinning Autonomous Learning Hub
Authors: Liton Dr. Hussain Ahmed
Published: February 2021

Social media enabled teaching learning.
Now the updated and revised manuscript is attached

herewith.
Right to Customization: Conceptualizing the Right to Repair for Informational Privacy
Authors: Tamo-Larrieux Aurelia , Zihlmann Zaira , Garcia Kimberly , Mayer Simon
Published: February 2021

Using a digital service is often framed in a binary way: Either one agrees to the service provider's data processing practices, and is granted access to the service, or one does not, and is denied the service. Many scholars have lamented these ‘take-it-or-leave-it’ situations, as this goes against the ideals of data protection law. To address this inadequacy, computer scientists and legal scholars have tried to come up with approaches to enable more privacy-friendly products and services. In this article, we call for a right to customize the processing of user data. Our arguments build upon technology-driven approaches as well as on the ideals of privacy by design and the now codified data protection by design and default norm within the General Data Protection Regulation. In addition, we draw upon the right to repair that is propagated to empower consumers and enable a more circular economy. We propose two technologically-oriented approaches, termed ‘variants’ and ‘alternatives’ that could enable the technical implementation of a right to customization. We posit that these approaches cannot be demanded without limitation, and that restrictions will depend on how reasonable a customization demand is.
EFEKTIFITAS PENGGUNAAN METODE DEMONSTRASI PADA PEMBELAJARAN FIQIH DI MA KAPETAKAN
Authors: Hakim Arif Rohman
Published: February 2021

Cara mengatasi kendala dalam solusi Hal tersebut antara lain: memotivasi siswa, memberikan arahan pelaksanaan pembelajaran Fiqih, meningkatkan infrastruktur untuk mendukung kegiatan belajar mengajar, memberikan evaluasi dan supervisi kegiatan siswa di sekolah, serta menambah jam sekolah. Hasil belajar berbasis data dalam pembelajaran siswa Diperoleh melalui angket yang disebarkan ke banyak subjek survei dari MA Kapetakan, kemudian dikumpulkan dan dianalisis melalui rumus distribusi frekuensi, terlihat bahwa di MA Kapetakan Cirebon, metode demonstrasi digunakan dalam pembelajaran Fiqih sangat efektif dalam kursus berikutnya. Hal ini berdasarkan jawaban dari narasumber pada tabel diskusi, dan terlihat dari kemampuan siswa yang sama-sama dapat memahami pelajaran dan praktik. Kesalahan saat mencoba menulis ulang. Periksa jumlah karakter atau karakter khusus.
A Review on Therapeutic strategies of Relapsed and Refractory Multiple Myeloma
Authors: Mukherjee Dattatreya
Published: February 2021

Improvement in treatment options in multiple myeloma (MM) makes the survival rate intodouble during recent years but most of the patient eventually relapses. The treatment of relapseand refracting MM is still now very complex. At the time of relapse, the use of alternative drugsis the current practice. Using Protease inhibitors like Bortezomib and immune-modulators likethalidomide gives a satisfactory treatment prognosis in MM. Now many new options areavailable like second and third generation protease inhibitor like carfilzomib and ixazomib, theimmune-modulator like lenalidomide, pomalidomide, the monoclonal antibody likedaratumumab, elotuzumab, Histone Deacetylase inhibitor, Kinesin Spindle inhibitor and NF-kB,MAPK, AKT inhibitors. Daratumumab, targeting CD38, has multiple mechanism of action likemodulation immunosuppressive bone marrow micro-environment. Daratuzumab has a goodprogression free survival when it is given with lenalidomide/ dexamethasone orbortezomib/dexamethsone. Autologous stem cell transplantation (ASCT) is important treatmentin relapsing and refracting MM. Donor lymphocytic infusion is a new and effective technique inthe treatment of relapsing and refracting MM. The advancement in the treatment of relapsed andrefractory MM has been discussed in this article. The final goal should be finding a balancebetween efficacy, toxicity and cost.
PEMBANGUNAN EKONOMI DESA DI SULAWESI SELATAN: Revitalisasi BMT sebagai unit usaha BUMDes
Authors: Suaib Andi Suwandi Putra
Published: February 2021

Salah satu lembaga keuangan mikro syariah yang telah eksis di tanah air adalah BMT. BMT memiliki subtansi dalam dirinya yang membedakannya dengan lembaga keuangan lainnya, tidak hanya berorientasi pada pengelolaan yang profit tetapi juga mempunyai peran sosial sehingga BMT memiliki potensi yang besar untuk dapat memberdayakan masyarakat dipedesaan. Revitalisasi BMT sebagai unit usaha BUMDes sangatlah dibutuhkan untuk merealisasikan pembangunan ekonomi desa di Sulawesi selatan. Peran pentingnya yakni optimalisasi dana desa dan sentralisasi distribusi harta di setiap desa.
WABAH ATAU VIRUS DALAM PERSPEKTIF ULUMUL QUR'AN
Authors: Munawaroh Novi Rojiyyatul
Published: February 2021

Abstrak :Virus merupakan suatu wabah yang sangat meresahkan bagi semua kalangan baik manusia atau pun makhluk hiduplainnya. Virus ini akan menjadi lebih menakutkan karena manusia merasa virus adalah sesuatu yang sangat mengancam keselamatan manusia. Dan pada tahun ini peristiwa yang berkaitan dengan virus sedang terjadi, yaitu maraknya virus yang menyerang manusia dikenal dengan virus corona atau covid 19. Sebagian besar manusia merasa hawatir dengan virus ini yang menyebabkan terganggunya kegiatan bersosialisasi antar individu. Covid 19 di masa ini juga menjadi penyebab terganggunya kegiatan baik itu kegiatan pendidikan dan kegiatan-kegiatan kemasyarakatan lainnya. Oleh sebab itu banyak sekali upaya yang sudah dilakukan untuk pencegahan dan pengobatan dari virus covid 19 ini, seperti disediakannya alat mencuci tangan di setiap tempat, memakai masker, membawa handsanytezer bahkan system sosialdistencing dan lockdown. Namun siapa sangka bahwa sejak zaman nabi masyarakat sudah mengenal dengan yang namanya virus atau wabah, karena pada masa kenabian dan kerasulan juga sudah terjadi hal tersebut. Dan tatacara menghadapinya sudah di ajarkan pula oleh nabi yang bisa kita lihat dan pelajari dari beberapa hadistnya. Metode penulisan data merupakan metode pengumpulan data, yang bisa di pertanggung jawabkan. Terealisasikannya gagasan ini akan menjadi solusi pengajaran terkait pencegahan dan cara menyikapi wabah terutama virus yang sedang marak sekarang ini yaitu covid 19.
Character in the British army: A precarious profession
Authors: Walker David Ian
Published: February 2021

Finding balance between institutional or bureaucratic inclinations and professional ones is a challenge for all professions, but this is especially difficult for the military profession owing to its unique role and the unusual pressures that are placed upon armed forces personnel. The military profession is charged with delivering violence for the benefit of wider society and by morally appropriate means. It is unique among professions by virtue of the authorised use of abhorrent methods and a requirement for personnel to be prepared to die in the performance of their duties. The special conditions of the military profession are further underscored by the supremacy of the mission and group over individual, such that at times institutional imperatives can dominate. The cultivation of appropriate professional military character is clearly a very complex endeavour, particularly when members of the profession must face some of the most challenging conditions imaginable. In this chapter, I shall focus on the British Army to argue that although the British Army Officer Corps is a profession, it must be considered a precarious one owing to an ongoing interplay between institutional and bureaucratic factors on the one hand and a requirement that Army officers exercise professional and ethical autonomy on the other. Moral aspects of the profession form the main emphasis of the chapter since a defining feature of any profession is its ethic or code of ethics (Bayles 1988, Oakley and Cocking 2002, Wolfendale 2009).
Influence of Naturalistic, Emotional Context and Intolerance of Uncertainty on Arousal-Mediated Biases in Episodic Memory
Authors: Reisman Samantha , Gregory David F. , Stasiak Joanne , Mitchell William John , Helion Chelsea , Murty Vishnu P.
Published: February 2021

Threat-related arousal is known to distort memory, biasing individuals towards perceptual details and away from contextual details. This work has mainly been conducted in laboratory settings, limiting the application of findings to real-world experiences. To test how threat-related arousal influences multi-featural memory for complex events, participants navigated an immersive haunted house while physiological arousal data was collected and later, recalled memories for the event after a 1-week delay. We found that threat-related arousal resulted in relatively fewer remembered events, but enhanced recall of perceptual details for events that were remembered. Further, the relationship between physiological arousal and perceptual bias was impaired in individuals with high intolerance of uncertainty, suggesting that uncertainty aversion may result in a generalization of threat-related perceptual biases to mundane events. These findings support a model by which heart rate and individual differences in uncertainty aversion interact to shape how threatening events are recorded in long-term memory.
Intrasexual and intersexual selection for neck musculature in men
Authors: Caton Neil , Lewis David M. G.
Published: February 2021

Over 150 years ago, Darwin (1871) argued that humans evolved to inflict and resist damage in violent combat. Until now, however, no research has examined the claim that humans have evolved anatomical structures to both better inflict and resist damage in real-world agonistic exchanges. Human neck musculature has long been theoretically implicated in force output and concussion resistance capacities, and we proposed that human neck musculature evolved to increase damage resistance (knockout resistance) and damage infliction (knockout power) in real-world violent combat. Larger neck musculature was indeed associated with greater fighting success, knockout resistance, and knockout power capabilities across 715 professional combatants, after comprehensively controlling for weight, height, age, fighter's debut date, sex, reach, leg reach, and facial structure (Study 1). We then discovered that human neck musculature is one of the most sexually dimorphic human anatomical features, when compared against over 70 other human anatomical features (Study 2; N = 6000). We then found that human psychological systems have evolved to generate social perceptions in response to neck musculature. Men with greater physiological neck strength are perceived as stronger fighters (Study 3, after controlling for weight, height, age, beardedness, and torso, arm, bicep, and lower body strength). Study 4 specifically showed that men with larger sternocleidomastoid and upper trapezius muscles -- muscles implicated in damage resistance and infliction, respectively -- are perceived as more dominant (i.e., strong, masculine, anger-prone, and aggressive) and attractive (i.e., short and long-term attractiveness). Our results comprehensively demonstrate that human neck musculature evolved to increase resource-holding potential in violent combat, for which human psychological systems have consequently evolved an attraction. Given that human neck musculature is novel to the psychological and biological sciences, implications are discussed for the research areas of formidability assessment, contest competition, violence, face perception, emotion recognition, attraction and relationship research, political and organisational psychology, sports performance, and biomedical research.
Development of Mathematic Learning Devices Based on Discovery Learning Model To Facilitate Students’ Mathematic Communication Ability
Authors: Khasanah Uswatun , Hutapea Nahor Murani , Zulkarnain Zulkarnain
Published: February 2021

The condition of the learning equipment used by the teacher is not in accordance with the demands of the 2013 curriculum. Learning activities and Student Worksheets (LKPD) used in the learning process have not been able to facilitate the improvement of students' Mathematical Communication Ability (KKM). Teachers have not designed learning tools that can encourage student activities to facilitate the improvement of KKM. This study aims to produce learning tools based on the Discovery Learning model to facilitate the improvement of the KKM of students that are valid and practical. This development research uses the ADDIE development model with the stages of Analysis, Design, Development, Implementation, and Evaluation. The products produced from this research on the development of learning tools are syllabus, lesson plans, LKPD and KKM questions. The results of the validation test for the syllabus, RPP, LKPD and KKM questions obtained consecutively a percentage of 92.19%, 93.37%, 93.14% and 94.64% with very valid categories. The practicality test results got a percentage of 84.52% for small group trials and 94.00% for teacher responses in the very practical category. The results of the validation and practicality test state that mathematics learning tools based on the Discovery Learning model can facilitate students' Mathematical Communication Ability.
Development of Mathematics Learning Tools with Problem Based Learning Model on Matrix Material to Facilitate Students' Critical Thinking Ability
Authors: Pertiwi Wiyana , Roza Yenita , Yuanita Putri
Published: February 2021

The ability of students to think critically in mathematics is is still low. The lack of learning tools that are considered to facilitate students' mathematical critical thinking skills is one of the cause it. The purpose of this study was to develop a mathematics learning tool with a quality problem-based learning (PBM) model to facilitate students' mathematical critical thinking skills. The learning tools developed consisted of a syllabus, lesson plans (RPP) and student worksheets (LKPD) on the matrix material for class X SMK. This research was a development research using the Borg and Gall model. The development consists of six stages, namely: 1) research and data collection; 2) planning; 3) development of the initial product draft; 4) initial field trials; 5) revised trial results; and 6) dissemination and implementation. The subject of this research trial was the students of SMK Nurul Falah Pekanbaru. The instrument used was validation instrument for the syllabus, lesson plans, and student worksheet. Based on the results of the validation data analysis, it shows that the learning tools developed were very valid. The results of the validation of the syllabus were 85.11; the average RPP score was 86.02; and the average LKPD score was 86.40. The average student response questionnaire to the initial field trial was 85.93 with the very practical category. The learning device developed was valid and practical for use by class X SMK students.
The Effectiveness of Collaborative Learning Throughtechniques on Group Investigation and Think Pair Share Students' Critical Thinking Ability on Chemical Equilibrium Material
Authors: Fauzi Fajrina , Erna Maria , Linda Roza
Published: February 2021

The purpose of this study was to determine the differences in the improvement of students' thinking skills using collaborative learning techniques Think-Pair-Share and Group Investigation. The research used was a quasi-experimental research design with non equivalent control posttest design. The data collection technique used critical thinking skills questions consisting of 5 essay test questions. Based on the research results of hypothesis testing using paired simple t-test , the results obtained were sig (2-tailed) <0.05, which means that collaborative learning of GI and TPS techniques is effective on critical thinking skills than the control class. Hypothesis testing is to see significant differences between collaborative learning. TPS and GI techniques used independent sample t-test and the results obtained were sig (2-tailed) <0.05, which means that there is a significant difference between collaborative learning of GI and TPS techniques on critical thinking skills. For the average percentage of critical thinking skills in the collaborative learning class, the Think-Pair-Share technique is 80.57% and Group Investigation is 76.73%, and in the control class it is 68.45%, which means the application of collaborative learning techniques Think-Pair- Share is more effectively used in improving students' critical thinking skills on chemical equilibrium material.
Common Fixed Point Theorems Using Compatible Mappings of Type (R) in Semi-metric Space
Authors: Rajopadhyaya Umesh , Jha K.
Published: February 2021

In this paper, we establish a common fixed point theorem for three pairs of self mappings in semi-metric space using compatible mappings of type (R) which improves and extends similar known results in the literature.
Pengaturan Perlindungan Data Pribadi Dalam Penggunaan Aplikasi Pedulilindungi
Authors: Nurhidayati Nurhidayati , Sugiyah Sugiyah , Yuliantari Kartika
Published: February 2021

PPandemi covid-19 sudah berlangsung selama 9 bulan,   dengan jumlah yang terpapar  terus  meningkat.  Berbagai upaya    dilakukan   pemerintah untuk mengurangi penyebaran wabah tersebut, salah satunya dengan meluncurkan Aplikasi PeduliLindungi. PeduliLindungi ditetapkan sebagai aplikasi yang membantu melakukan Tracing, Tracking, Fancing melalui infrastruktur, sistem dan aplikasi telekomunikasi yang terhubung dengan data center dalam negeri. Penelitian ini bertujuan untuk mengetahui  perlindungan data pribadi bagi pengguna Aplikasi PeduliLindungi. Metode Penelitian melalui studi literatur, dengan data sekunder, menggunakan bahan hukum primer, sekunder, tersier, dengan mengkaji berbagai peraturan,  mengingat sampai saat ini belum ada undang-undang yang mengatur  tentang perlindungan data pribadi. Hasil penelitian menunjukkan Perlindungan data pribadi pengguna  aplikasi ini didasarkan pada peraturan yang mengatur tentang Teknologi  Informasi dan Komunikasi, Kesehatan, dan Pelaksanaan administrasi Kependudukan, meskipun pemerintah memberikan jaminan keamanan bagi pengguna PeduliLindungi, namun sampai saat ini pengguna aplikasi PeduliLindungi masih  kurang diminati. Harapan kedepannya semakin banyak yang mengunduh PeduliLindungii, sehingga dapat menekan angka penyebaran covid-19. Selain itu pentingnya segera disahkan undang-undang perlindungan data pribadi untuk memberikan kepastian hukum.
Peran Sensitivitas Harga dalam Memoderasi Minat Pembelian
Authors: Nugraha Kristian Suhartadi Widi , Maliki Bachtiar
Published: February 2021

Penelitian ini bertujuan untuk mengetahui bagaimana peran sensitivitas harga sebagai moderasi dari kualitas produk, periklanan dan perceived risk terhadap minat pembelian. Sampel diambil dengan teknik purposive sampling dengan mengambil 120 responden. Analisis data menggunakan SEM-PLS menggunakan smartpls 3.0. Hasil penelitian menunjukkan bahwa kualitas produk berpengaruh signifikan terhadap minat pembelian, periklanan berpengaruh signifikan terhadap minat pembelian dan perceived risk berpengaruh signifikan terhadap minat pembelian, namun sensitivitas harga hanya dapat memoderasi periklanan terhadap minat pembelian. Sedangkan pada kualitas produk dan perceived risk, sensitivitas harga tidak memoderasi. Kata Kunci: kualitas produk, periklanan, perceived risk, sensitivitas harga,minat pembelian