bluuebunny/crossref_metadata_2025 huggingface dataset:
Left Behind Economically or Politically? Economic Grievances, Representation, and Populist Attitudes
Authors: Habersack Fabian , Wegscheider Carsten
Published: September 2024

Research on the relationship between discontent and populist attitudes abounds. However, whether this discontent arises in response to economic grievances or a perceived lack of representation remains understudied. While previous research has considered both as independent factors, we assume their interaction drives populist attitudes. We argue that deprivation and sentiments of being left behind exacerbate the feeling that one’s policy positions are not recognized and represented in politics. To test this claim empirically, we draw on recent data from the German Longitudinal Election Study of 2021. We combine egocentric and sociotropic indicators of being left behind and interact these with the perceived distance of one’s own policy positions to the positions of the opposition and government parties represented in parliament. We find that both perceptions of personal and societal deprivation, as well as a greater perceived distance from the government, are associated with populist attitudes. Furthermore, we find that the effect of distance from the government is contingent on someone’s economic position, albeit the direction of the interaction effect contradicts our initial expectations: The effect of perceived ideological distance from the government on populist attitudes is primarily reinforced among those who are better off rather than for those who struggle economically. This implies that populist attitudes ought to be addressed depending on the source of discontent rather than treating populism as a general expression of indiscriminate protest. Our analysis contributes to understanding the various origins of populist attitudes and to developing possible ways of mitigation.
Walking to School: What Streets Do Children Prefer?
Authors: Michail Nafsika , Ozbil Torun Ayse
Published: September 2024

Active school travel provides children with a daily opportunity to engage actively with their local urban environments. Despite widespread recognition that understanding the underlying factors of children’s navigation choices is crucial for developing effective environmental interventions to promote active school travel, there is limited evidence on children’s experiences regarding their school journeys. This is due in part to the fact that most studies rely on GIS-calculated routes which may not adequately represent children’s actual home-school journeys, and hence actual experiences. This study aims to identify specific environmental attributes influencing children’s navigation choices based on children’s (9–10 year olds) actual walking routes to school in Newcastle upon Tyne, UK. 45 pairs of selected and avoided streets were compared using a range of urban form (e.g., street connectivity measured through space syntax variables) and street design (e.g., footpath width) characteristics. Statistical analysis highlighted significant design attributes as potential determinants of navigation selections. In-depth street-level observations provided insight into the urban character of these street pairs, identifying the environmental qualities that could offer opportunities for active and safe commuting among children. This study contributes to the literature by broadening our understanding of the environmental attributes that may promote active school travel. Our findings, based on children’s actual experiences, may also inform urban planners and designers on designing inclusive child-friendly cities.
Specifics of Psychological Safety of Teachers of Russian Universities in Modern Conditions
Authors: Prjazhnikov N.S.
Published: September 2024

The article clarifies the concept of “psychological safety” taking into account the specifics of modern Russian universities. The foundation of such security is the self-esteem of the teacher, who is capable of realizing the highest meanings of his profession even under unfavorable conditions and with disrespectful attitude towards himself. A generalized model of possible factors and risks influencing psychological safety is proposed, among which not only traditionally unfavorable factors are highlighted, but also overly favorable ones, which can lead to excessive “calmness” of the teacher and reduce his creative activity. A typology of possible risks to psychological well-being is proposed, which presupposes the teacher’s readiness for retrospective, situational and prospective reflection of his work. Options for preventing risks to psychological well-being are also considered, based on the teacher’s willingness to make a reasonable compromise when dubious directives are followed if they do not threaten self-esteem and at the same time there are opportunities for more decent work.
Design, Synthesis and Cholinesterase Inhibitory Activity of Novel 1,3,4-Thiadiazole Derivatives
Authors: Kaya Betül , Acar Çevik Ulviye , Çiftci Bilge , Isık Mesut , Kaplancıklı Zafer Asım , Beydemir Şükrü
Published: September 2024

Inhibition of the cholinesterases (AChE and BChE) plays a pivotal role in the symptomatic treatment of Alzheimer’s disease. The present study reports the synthesis and anticholinesterase activity of five novel thiadiazole analogs in search of anti-Alzheimer agents. The structures of the newly synthesized compounds were characterized using 1H NMR, 13C NMR and HRMS. Tested compounds inhibited acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes with IC50 values in the range of 8.250-20.382 μM and 14.143-0.986 μM, respectively. N-(4-Chlorophenyl)-2-[(5-(allylamino)-1,3,4-thiadiazol-2-yl)thio]-N-(3-nitrobenzyl)acetamide (6e) was determined as the most potent inhibitor against both tested enzymes when compared with standard drug tacrine. Molecular docking study was carried out to reveal the binding interactions between compound 6e and the active site of AChE
Static Magnetic Field Focusing With Neodymium Magnets For Wound Healing: A Numerical Study
Authors: Aydın Elif Feyza , Zengin Reyhan
Published: September 2024

Static magnetic fields (SMFs) find widespread applications in diverse scientific, technological, and medical domains. This study explores the potential of neodymium permanent magnets in focusing and controlling SMFs, specifically emphasizing wound healing applications. Numerical simulations using COMSOL Multiphysics create a uniform static magnetic field for wound healing. The study systematically increases the number of neodymium magnets, demonstrating enhanced magnetic flux density and a focused magnetic field. The results affirm the efficacy of neodymium magnets in generating a uniform static magnetic field between 160-600 m Tesla. This research proposes neodymium permanent magnets as a promising tool for wound healing applications, offering a non-invasive and focused therapeutic approach. While the study provides valuable insights, further experimental and clinical validations are necessary to establish the real-world efficacy of this method. The work contributes to the evolving understanding of static magnetic fields as a viable therapeutic modality for various medical conditions, particularly in the context of wound healing.
Supramolecular Solvent Liquid Phase Microextraction of Voriconazole İn Pharmaceutical and Environmental Samples With High Performance Liquid Chromatography Detection
Authors: Yılmaz Erkan , Yıldız Gülnihal
Published: September 2024

In this study, a new analytical method based on the supramolecular solvent liquid phase microextraction (Ss-LPME) and HPLC was developed for the analysis of voriconazole as an active drug in the class of antifungals with a wide spectrum of action at trace levels. Nano/micro sized supramolecular phase formed in 1-decanol, tetrahydrofuran and aqueous environment was used as extraction agent for separation and preconcentration of trace level of voriconazole. For the optimization of the Ss-LPME method, important analytical parameters such as the effect of sample solution pH, volume of 1-decanol, amount of THF, ultrasounic irridation time, centrifugation time and sample solution volume on the extraction efficiency were evaluated. Optimal conditions of the Ss-LPME; pH: 8, 1-decanol volume: 200 µL, THF volume: 300 µL, ultrasounic irridation time:10 min and centrifugation time: 8 min. For the developed Ss-LPME/HPLC procedure, the limit of detection (LOD), limit of quantification (LOQ) and enhancement factor (EF) were found 2.7 µg·L-1, 8.8 µg·L-1 and 36, respectively. The Ss-LPME/HPLC procedure was applied to waste water, lake water and drug samples. The fact that recovery values ranging from 100% to 108.5% were obtained for these real samples proved that this method can be used successfully in the matrix environments studied
Geometry Optimization, Molecular Docking and ADMET Studies of Echimidine Molecule
Authors: Bıçak Bilge
Published: September 2024

Plants are an important food group that has been used as a source of nutrition and healing from past to present. Plants contain secondary metabolites that are still under investigation in drug development studies. Alkaloids, which are secondary metabolites, have antioxidant and antibacterial properties as well as therapeutic potential in various diseases such as Alzheimer's disease. Acetylcholinesterase (AChE) inhibitors come to the fore in the treatment strategy of Alzheimer's disease. Echimidine, a pyrrolizidine alkaloid, is an important compound known to be active in AChE inhibition. Molecular docking method has an important place in elucidating biochemical processes by examining the interactions of drugs or drug candidates with the receptors targeted for the disease. Additionally, information on the absorption, distribution, metabolism, excretion, and toxicity (ADMET) of drug candidate molecules is important in drug development studies. In this study, echimidine molecule was optimized, the molecular docking study was carried out with AChE and the interaction types, binding profile, and binding affinity of echimidine was determined. ADMET analysis of echimidine was also realized to estimate its drug potential. With this study, geometry optimization of the molecule, elucidation of its interactions with AChE, and prediction of its pharmacokinetic properties were achieved for the first time.
In Vitro Antioxidant Assessment of Methanol and Water Extracts of Anthemis kotschyana Boiss. var. kotschyana
Authors: Güçlü Gülşen
Published: September 2024

The genus Anthemis, with approximately 130 species globally, is significant within the Asteraceae family and is widely used in traditional medicine. Studies on the biological activity of Anthemis kotschyana, an endemic species found in Turkey, are limited. This study investigated the chemical constituents and antioxidant activity of Anthemis kotschyana using two different extracts, methanol and water. The major components of the plant were determined by GC‒MS. According to the data obtained, the major component was found to be "2-propenoic acid, a tridecyl ester" in the water extract and "cyclododecane" in the methanol extract. When the DPPH and ABTS radical scavenging activities were analysed, the methanol extract was found to be more active than the water extract in the DPPH experiment, while the opposite was observed in the ABTS experiment. The TPC was greater than the TFC based on the acquired results. The TPC of the water extract was 83.7 ± 15.6 mg GAE/g, the TPC of the MeOH extract was 170.7 ± 17.4 mg GAE/g, and the TFC of the water extract was 24.3 ± 7.2 QE/g, while the TFC of the MeOH extract was 65.6 ± 5.3 QE/g. For both substances, the amount of methanol extract was greater than that of the water extract. In conclusion, further studies on this species, known for its antioxidant activity and potential as a source of phenolic compounds, could support its use as a therapeutic agent in the future.
Determination of Cytotoxic Activity of Aronia melanocarpa (Michx.) Elliot Fruit Extracts on Breast Cancer (MCF-7) and Cervical Cancer (HeLa) Cell Lines
Authors: Sönmez Gürer Eda , Altıntaş Ayhan
Published: September 2024

Aronia (chokeberry) fruits are consumed as fresh fruit due to their high antioxidant activity, and are also preferred among the public in the production of natural medicines. Aronia melanocarpa (Michx.) Elliot, a species of the Rosaceae family, contains many phytochemical compounds such as flavonoids, phenolic compounds, lignans, terpenes, tocopherols, phospholipids, organic acids and high amounts of anthocyanins. In this study, it was aimed to determine the in vitro anticarcinogenic activities of A. melanocarpa (Michx.) Elliot fruit extracts prepared with 6 different solvents. In the study, the cytotoxic effects of the fruits were investigated using breast cancer cell line (MCF-7) and cervical cancer cell line (HeLa), and their effects on healthy cells were investigated using human endothelial cells (HUVEC) and mouse fibroblast cells (L929) by the MTT method. As a result of the study; It was determined that the highest cytotoxicity on the breast cancer (MCF-7) cell line was observed in the ethanol extract (IC50=111.44 µg/mL) and the lowest cytotoxicity was observed in the hexane extract (IC50=661.80 µg/mL). It was determined that the highest cytotoxicity on the cervical cancer (HeLa) cell line was observed in the ethanol extract (IC50=95.14 µg/mL) and the lowest cytotoxicity was observed in the ethyl acetate extract (IC50=319.51 µg/mL). According to these values; It was determined that all extracts of Aronia fruit had cytotoxic effects on MCF-7 and HeLa cell lines, selectivity index values were higher in HeLa cells, and they did not have cytotoxic effects on HUVEC and L929 healthy cell lines (IC50=411.25-663.27 µg/mL). Thus, it has been determined that the fruits of the Aronia melanocarpa species are promising in the development of new natural resources, new drugs and therapeutic agents in cancer treatment, thanks to their anticancer activities and low cytotoxicity. It is recommended that further research be conducted on the mechanisms of anticancer activity in the future
The Investigation of Bunching and No Bunching Regions of Sinusoidal Mounds
Authors: Tüzemen Ahmet Türker
Published: September 2024

We studied the evolution of an initial surface which was sinusoidal mound shaped for Diffusion Limited (DL) regime. We supposed that there were two dimensional concentric circular steps on initial surface and attractive/repulsive interactions between these monoatomic steps. While following the surface's evolution, the equation of motion related to each step radius's change and diffusion equation have been solved. We obtained bunching and no bunching regions of studied initial surfaces in a parameter space with their scaling characteristics. Our results in this examination can be summarized as; bunching (no bunching) region expands (shrinks) with increasing of wavelength or amplitude of the initial surface. The curves separating bunching/no bunching regions scale with each other. In the case of the amplitude (wavelength) is changed, the scaling factor is (A_0⁄(A_0^' ))^(1/6) ((λ⁄λ^' )^(1/2)). When both the wavelength and amplitude of the surface are changed at the same time, the scaling factor is equal to (A_0⁄(A_0^' ))^(1/6)×(λ⁄λ^' )^(1/2).
Optimized Deep Eutectic Solvent System for Liquid Phase Microextraction of Brillant Blue FCF in Diverse Analytical Food Matrices
Authors: Kızıl Nebiye
Published: September 2024

This study introduces a novel microextraction technique for the analysis of Brilliant Blue FCF, a widely used food dye, employing a deep eutectic solvent (DES). The method aligns with green chemistry principles by favoring environmentally benign solvents, ensuring rapid and efficient extraction. Specifically, a DES composed of tetrabutylammonium bromide (TBAB) and phenol (Ph) was prepared in a cost-effective and expedient manner. To enhance extraction efficiency within the deep eutectic solvent-based dispersive liquid-liquid microextraction (DB-DLLME), critical parameters such as the volume of DES, quantity of dispersive agent, extraction time, and sample volume were systematically optimized. The accuracy of the method was conducted at pH 3 by spiking various food samples with known concentrations of the analyte. Analytical performance metrics, including recovery efficiency, limit of detection (LOD), limit of quantification (LOQ), and relative standard deviation (RSD), were determined and reported as 0.86 µg/L, 2.88 µg/L, and 0.4-1.3% respectively. Furthermore, the method has been successfully utilized for analyzing samples of confectionery, beverages, water, and chewing gum.
Calculation of resistance force at firm clay digging with a cylindrical bucket
Authors: Buryi Grigory G.
Published: September 2024

BACKGROUND: The performance of single-bucket hydraulic excavators affects many areas of activity. This parameter of the machine largely depends on the volume of the material being moved. However, the bucket resistance forces do not allow large buckets to be installed on an excavator.
AIM: The paper discusses the design of the bucket which resistance to digging is reduced when it embeds into the ground. This statement has to be verified.
METHODS: For this aim, the process of embedding the bucket into firm dry clay is considered. This kind of soil is the most difficult to be processed. Since there is no viscosity in this soil, the equations of spatial problems of elasticity theory are used to describe the process. A number of assumptions are made, and the system of differential equations describing stresses in the soil is solved.
RESULTS: The result of the solution is the obtained dependence for determining the normal pressure from the soil in the process of its destruction, which helps to determine the overall digging resistance force. The initial parameters of the soil and bucket of the proposed design, developed for the excavator based on the YuMZ tractor, are described. The initial parameters are substituted into the resulting solution.
CONCLUSION: The obtained value of the digging resistance force is significantly lower than the force that the hydraulic drive of an ordinary excavator has to overcome.
ANALISIS PENDAPATAN DAN NILAI TAMBAH AGROINDUSTRI TEMPE DAN TAHU (STUDI KASUS: DESA PULO JANTAN, KECAMATAN NA-IX-X, KABUPATEN LABUHANBATU UTARA)
Authors: Tanjung Mhd Rizki Hamdani , Suswati Suswati , Harahap Gustami
Published: September 2024

Salah satu industri pengolahan kedelai yang potensial adalah industri tempe dan tahu. Pengolahan tempe merupakan salah satu produk potensial yang dapat dikembangkan karena hingga 50% konsumsi kedelai Indonesia digunakan untuk pembuatan tempe, 40% untuk tahu dan 10% untuk produk lainnya. Terdapat beberapa industri yang berada di Desa Pulo Jantan, Kecamatan Na-IX-X, Kabupaten Labuhanbatu Utara salah satunya industri Makmur sejahtera yang bergerak pada industri tahu dan tempe, dengan menggunakan kedelai sebagai bahan baku produksinya. Industri Makmur Sejahtera melayani permintaan di sekitar wilayah Kabupaten Labuhan Batu Utara. Metode yang digunakan dalam penelitian ini adalah metode Hayami. Metode pendekatan dalam penelitian ini adalah metode kualitatif dan metode kuantitatif. Hasil dari penelitian yang diperoleh Adalah adanya perbedaan nilai tambah kedelai pada produksi tahu dan tempe sebesar 44% atau sekitar Rp41.831/kg kedelai yang diolah pada UKM Bapak Angga dan sebanyak 55% atau sekitar Rp41.498/kg kedelai yang diolah pada UKM Ibu Suarni.Kata Kunci: Kedelai, Produksi Tahu-Tempe, Pendapatan,kecamatan Na – IX- X
Trends in Influencer Marketing: A Bibliometric Analysis and Future Directions
Authors: Erdoğan Hamit , Mucan Özcan Burcu
Published: September 2024

Influencer marketing is one of the trending research topics in marketing. In this context, this study aims to bibliometrically evaluate the work published by academics about influencer marketing. Bibliometric analysis was applied to 1584 English articles in the Scopus database containing the subject title of influencer marketing and its synonyms. The data were analyzed under four headings—information of published articles, citation analysis, word cloud and author information—through the R program version 4.2.2. Additionally, the Voyant Tools text analysis program was used in some analyses. The research results will provide a detailed report on English articles in the Scopus database regarding influencer marketing between 2002 and 2022. It is thought that the research results will provide a general guide for future studies on influencer marketing.
Havacılıkta Ekip Kaynak Yönetimi ve Emniyet Kontrol Odağı İlişkisi: Öz Yeterlilik ve İş Akış Deneyiminin Rolü
Authors: Erceylan Nusret , Atilla Gaye , Eryılmaz İnan
Published: September 2024

Bu araştırma, havayolu pilotlarının emniyet kontrol odaklarının ekip kaynak yönetimine ilişkin tutumları üzerindeki etkisinin belirlenmesi ile bu ilişkide pilotların öz yeterlilik ve iş akış deneyimlerinin ayrı ayrı ve seri aracılık rollerinin sorgulanması amacıyla yürütülmüş, elde edilen sonuçlar ile uygulayıcılara EKY etkinliklerini geliştirici tavsiyelerde bulunulması amaçlanmıştır. Araştırma verileri Türkiye’de çalışmakta olan 410 havayolu pilotundan anket yöntemiyle toplanmıştır. Araştırma hipotezleri, oluşturulan yapısal eşitlik modellemeleri ve aracılık analizleri ile test edilmiştir. Elde edilen bulgular, havayolu pilotlarının emniyet kontrol odaklarının bu pilotların ekip kaynak yönetimi tutumları üzerinde yordayıcı etkisi olduğunu göstermiş olup, öz yeterlilik ve iş akış deneyiminin bu ilişkide ayrı ayrı ve seri çoklu aracılık rolüne sahip olduğunu, ayrı bağımsız değişkenler olarak da ekip kaynak yönetimini yordadıklarını ortaya koymuştur.
Algılanan Örgütsel Destek ile Örgütsel Bağlılık Arasındaki İlişkinin İncelenmesi: Sağlık Çalışanları Üzerine Bir Araştırma
Authors: Uyar Seda
Published: September 2024

Bu araştırmanın amacı algılanan örgütsel destek ile örgütsel bağlılık arasındaki ilişkiyi incelemek ve algılanan örgütsel destek ve örgütsel bağlılığın demografik faktörlere göre farklılıklarını tespit etmektir. Araştırmanın evrenini Erzurum’da faaliyet gösteren bir kamu hastanesindeki tüm sağlık çalışanları oluşturmaktadır. Araştırmanın örneklemini ise bu kamu hastanesinde görev yapmakta olan 338 sağlık çalışanı oluşturmaktadır. Araştırmanın verileri toplanırken ilk olarak sağlık çalışanlarının demografik özelliklerini ölçen bilgi formundan yararlanılmıştır. Sonrasında algılanan örgütsel destek Ölçeği ve Örgütsel Bağlılık Ölçeği sorularına yer verilmiştir. Araştırma amacı doğrultusunda bağımsız gruplarda t testi ve bağımsız gruplarda tek yönlü varyans (ANOVA) analizi ve ölçek ve alt gruplar arasındaki ilişkinin yönünü tespit için de korelasyon analizi yapılmıştır. Araştırma sonucunca algılanan örgütsel destek ile örgütsel bağlılık ve alt boyutları olan duygusal, normatif ve devam bağlılığı arasında pozitif yönde anlamlı bir ilişki tespit edilmiştir. Sağlık çalışanlarının çalışma saatleri, hastanedeki çalışma pozisyonları ve medeni durumları ile örgütsel bağlılık ve alt boyutlarından olan normatif bağlılık ortalamalarında anlamlı bir fark tespit edilmiştir. Cinsiyet, yaş ve aylık gelir durumu ile örgütsel bağlılık, duygusal bağlılık, devam bağlılığı, normatif bağlılık ve algılanan örgütsel destek ortalamalarında anlamlı bir fark tespit edilememiştir.
Üniversite Öğrencilerinde Dijital Oyun Bağımlılığının Duygu Düzenleme Güçlüğüne ve Sosyal Kaygı Düzeyine Etkisinin İncelenmesi
Authors: Altıok Sevim , Kahraman Sait
Published: September 2024

Bu çalışma, internet erişimi ve dijital materyallerin artmasıyla üniversite öğrencileri arasında yaygınlaşan dijital oyun bağımlılığının, duygu düzenleme güçlüğü ve sosyal kaygı düzeyi üzerindeki etkisini incelemiştir. Çalışma, Manisa ilindeki üniversitelerde eğitim gören 406 bireyle yürütülmüştür. Örneklem, rastgele örnekleme yönteminde kullanılmış olup, örneklemin içerisinde 273 kadın ve 133 erkek bulunmaktadır. Araştırmada “Yetişkinler için dijital oyun bağımlılığı ölçeği”, “Sosyal Kaygı Ölçeği”, “Duygu Düzenleme Güçlüğü Ölçeği” ve “Kişisel Bilgi Formu” kullanılmıştır. Toplanan verilerin analizi için SPSS 27 yazılımında Pearson Korelasyon Analizi, Çoklu Doğrusal Regresyon Analizi, Bağımsız Gruplar t-Testi ve ANOVA testleri kullanılmıştır. Çalışmanın neticesinde dijital oyun bağımlılığı ile duygu düzenleme güçlüğü ve sosyal kaygı düzeyi arasında pozitif korelasyon sonucu elde edilmiş olup erkeklerde bağımlılık düzeyi daha yüksektir. Regresyon analizlerine göre dijital oyun bağımlılığının sosyal kaygı üzerinde yordayıcı etkisi vardır. Duygu düzenleme ve sosyal kaygı değişkenleri bağlamında değerlendirdiğimizde kadınların dijital bağımlılık düzeyinin artması bu iki değişkeni erkeklere oranla daha fazla etkilenmektedir.
Editorial: Perspectives on Machine Learning
Authors: Haw Su-Cheng
Published: September 2024

Progress in machine learning technology has truly impacted our lives by tailoring many of our daily experiences to be seamless and intuitive. This innovation has brought about changes in day-to-day routines; from suggesting music based on our emotions to offering recommendations for places to visit or meals to try out. This special issue explores various Machine Learning technologies. Among some are Machine Learning advances that improve human interaction, predict user behaviours, analyse user reviews, and optimize high-risk investments like Bitcoin trading. These technologies enhance user experiences, help businesses refine marketing strategies, and provide quick insights from vast amounts of information, elevating AI to new heights. With the rise of transformation into advanced technologies taking prominence in our lives, we expect to see these machine learning innovations being integrated across many sectors and uses.
Data Perception and Information Disorder in the Italian Context During the Pandemic
Authors: Ciofalo Giovanni , Ugolini Lorenzo , Ciammella Fabio
Published: September 2024

This paper aims to learn how Italian audiences received and perceived data-driven television news during the Covid-19 pandemic. During this time, the logic and practices of creating and consuming television journalism were disrupted by the pandemic emergency. The paper presents the results of research carried out as part of a wider project titled “The Social Effects of Fake News” which was conducted from 2018 to 2022 within the CoRiS department of Sapienza University of Rome. The research project was reshaped in 2020, to understand the effects of what has been called “information disorder” in the areas of health, medicine, and science at a time when, together with the pandemic, an “infodemic” also emerged.1 We use Wardle and Derakhshan’s notion of “information disorder” as presented in their Council of Europe report.2
The results of the survey research we conducted show a surprising paradox. We found an interesting pattern of receiving and using information content based on data, in which users trust those who produce and validate certain data and at the same time do not believe that same data. This pattern of use indicates a particular approach to dealing with news among the Italian public. We have labelled it “know-it-all.” This article aims to deepen the understanding of this paradox of trust in experts but not in the data they deliver and how journalistic practice should deal with this conundrum.
Data Journalism, Digital Verification and AI. The Case for Newsroom Convergence
Authors: Postma Laura
Published: September 2024

This article discusses the opportunities and challenges of implementing data journalism, digital verification and AI in the centre of the newsroom. Data journalism, digital verification and fact-checking continue to be seen like jobs for specialists. As has AI, they have all entered newsrooms in various forms over the past two decades. This article comes out of preparatory work for an online course on data literacy for journalism, communication and creative industries students called MediaNumeric. The course focuses on search and exploration of data, digital skills, and tracking and debunking misinformation. As part of this special issue, this article wants to offer a sense of what is at stake in data entering newsrooms, and editorial and media production offices.
Agronomic dataset on potato growth and yield in the Netherlands
Authors: Ten Den Tamara , Van de Wiel Inge , Van Ittersum Martin , Van Evert Frits , De Wit Allard , Reidsma Pytrik
Published: September 2024

Data was collected at two field locations in the Netherlands: on the clayey soils in Lelystad and the sandy soils of Vredepeel during 2019 and 2020. The original aim of this dataset was to calibrate and evaluate crop growth models for estimating potential, water-limited and nitrogen-limited yield levels for modern potato cultivars. Therefore, treatments include different cultivars, irrigation regimes, nitrogen fertilization, and light interception. During the two seasons extensive data was collected either passively, via non-destructive or via destructive measurements. Passive measurements consisted of weather and soil moisture data and were taken continuously throughout the season. Non-destructive data was collected on photosynthesis, reflection/light intensity, SPAD chlorophyll values, plant height, crop phenology, and groundwater level roughly every other week throughout the seasons. Destructive measurements were taken on biomass (leaves, stems and tubers), leaf area, NPK content (leaves), and the number of tubers between five and seven times per season. Additionally, during the final harvest data was collected on the tuber size distribution, marketability, and NPK content of the tubers.
Magnitude of sympathovagal imbalance and its correlation with inflammatory response and oxidative stress in pregnant women at risk of pregnancy induced hypertension: a cross-sectional study
Authors: K. Vidya Karpagam , Pal Gopal Krushna , Habeebullah Syed , S. Velkumary , R. Soundaravally
Published: September 2024

Background: Pregnancy-induced hypertension (PIH) is a common complication of pregnancy but it’s genesis isn’t known. It is proposed to be due to an excessive inflammatory response in the mother secondary to placental or maternal factors. The study aimed to measure the magnitude of sympathovagal imbalance (SVI) and to evaluate the role that oxidative stress and the inflammatory response play in the development of sympathovagal imbalance in pregnant mothers with risk factors of pregnancy-induced hypertension.
Methods: A cross-sectional study was carried out among pregnant women with at least one risk factor for PIH and age-matched pregnant women without risk factors for PIH as controls from March 2023 to February 2024 in a tertiary care hospital in Pondicherry. The intergroup differences in the mean between the two groups were compared using the Mann Whitney test and the Student's T-test.
Results: Short-term heart rate variability was significantly higher among cases while time domain analysis didn’t show significance. Total Cholesterol (TC), Triglycerides (TG), Very Low-Density Lipoprotein (VLDL) and Low-Density Lipoprotein (LDL) were significantly higher among the cases and High-Density Lipoprotein (HDL) was low in cases compared to controls. There is a strong correlation of Low Frequency to High Frequency (LF-HF) ratio with Tumor Necrosis Factor-alpha (TNF-α) and high sensitivity (hs-CRP) in patients with risk factors of PIH.
Conclusions: Pregnant women at risk of pregnancy-induced hypertension showed increased inflammatory response, oxidative stress and dyslipidaemia. Hence, conducting sessions for stress management not only during pregnancy but also in the pre-pregnancy period can alleviate sympathetic dysfunction.
Effect of smartphone use on sleep and mental health status of Indian medical students: a cross-sectional study
Authors: Haque Shiraza , Singh Shraddha , Narayan Jagdish , Tripathi Adarsh , Ahmad Manzoor , Kumar Toyaj , Verma Shivam
Published: September 2024

Background: In today's digital era, technology plays an integral role in daily life, particularly among students facing significant health challenges associated with increased screen time. The increased screen usage has been linked to deteriorating physiological and psychological well-being, contributing to physical inactivity, and a sedentary lifestyle, leading to serious health conditions such as obesity, depression, and disrupted sleep patterns. Medical students are particularly susceptible to these effects due to prolonged screen use, which compromises both their mental and physical health and increases the risk of addiction. This study aims to explore the impact of digital screen time on sleep quality, cardiometabolic health, and mental health conditions such as depression, anxiety, and stress among medical students.
Method: A cross-sectional study was conducted at the Department of Physiology, KGMU, Lucknow, involving 113 medical students. Data collection utilized a structured questionnaire alongside validated instruments: PSQI for sleep quality assessment, DASS21 for psychological distress evaluation, and SAS-SV for smartphone addiction screening.
Results: The findings revealed that participants reported high average smartphone usage (8.84±10.62 years) and screen time (49.98±15.17 hours weekly). Statistical analysis demonstrated significant associations between smartphone dependency (p<0.0001), psychological distress (p<0.0001), and compromised sleep quality (Global PSQI score: 6.87±3.84) highlighting prevalence of disrupted circadian rhythms and compromised health.
Conclusion: This study highlights the critical need for guidelines on screen usage based on age, lifestyle, and professional demands and regulating screen use early can mitigate its detrimental health consequences, including disturbed sleep and mental health.
A case report on unusual cause of childhood obesity and visual disturbances-Bardet-Biedl syndrome
Authors: Panuganti Suresh Kumar , Modi Sujeeth Kumar , Patel Pooja Nilesh , Boda Sudha
Published: September 2024

Bardet-Biedl syndrome (BBS) represents a rare genetic condition distinguished by a multifaceted set of clinical features, including obesity, retinal dystrophy, polydactyly, renal dysfunctions, and cognitive dysfunction. BBS mostly affects children of consanguineous marriages. It is frequently overlooked during initial pediatric examinations. The lack of syndromic diagnostic strategy for identifying genetic disorders by healthcare professionals is being acknowledged as a significant concern. Here, we reported a patient (9 year 4 months old male) born to second degree consanguineous parents, who presented with major features of Bardet-Biedl Syndrome (BBS). The patient came to us with the symptoms including increasing weight gain and visual disturbances. In our case, the diagnosis was made after a comprehensive clinical assessment and genetic testing. Genetic testing showed that the patient had a heterozygous missense variant of the BBS10 gene (chr12: g.76347012 C>A; Depth: 117x). This result confirmed the diagnosis of Bardet-Biedl-Syndrome. This case report highlights a patient diagnosed with BBS, focusing on the clinical manifestations, genetic characteristics and potential avenues for future research.
Corticosteroid-induced Glaucoma: An avoidable blindness
Authors: Ajith Gayathri , Bhava Saravana , Kannan Rajesh , Subramaniam Bala
Published: September 2024

Healthcare professionals frequently advise the use of topical steroid eye drops to manage and control postoperative inflammation following phacoemulsification. Although there are many benefits associated with steroid usage, it is imperative to recognize the potential negative repercussions that may arise. In individuals who respond to steroids, the use of topical steroid drops can lead to an increase in intraocular pressure (IOP). Increase in IOP resulting from the side effects of steroids typically manifests several weeks following the initiation of eye drop therapy. The first documentation of steroid induced glaucoma (SIG) can be traced back to the 1950s on the administration of systemic adrenocorticotropic hormones. The elevation of IOP is a complex issue influenced by various factors, but the primary factor is the increased resistance within the outflow mechanisms of the trabecular meshwork. Out of all the risk factors related to ocular hypertension caused by steroid use, a preexisting glaucoma diagnosis is the most frequently seen. The usage of different routes of steroids administration has been linked to the occurrence of ocular hypertension. The current management approach prioritizes the exploration of steroid-sparing treatment options, discontinuing steroid use, employing medications to lower intraocular pressure, and considering interventional laser and surgical procedures.
Efficacy of topical autologous serum versus preservative free artificial tears in patients having isotretinoin induced dry eye diseases
Authors: Tripathi Ila , Sen Snigdha , Yadav Himanshu K , Jain Anu , Chahar Yatendra , Maurya Rajendra Prakash
Published: September 2024

Aim of this study was to compare the efficacy and safety of topical autologous serum versus preservative free artificial tears in management of systemic Isotretinoin induced dry eye

In this prospective observational analytical study a total of 182 eyes of 97 patients with systemic Isotretinoin induced dry eye were enrolled. Baseline evaluations including the ocular surface disease index (OSDI) scoring, Schirmer’s test, tear film break up time (TBUT) and National Eye Institute (NEI) grading for corneal and conjunctival staining were performrd. All study subject were underwent thorough ophthalmic examinations including best-corrected visual acuity (BCVA) assessments and intraocular pressure measurements. The study participants were divided into two groups: group I treated with 40% autologous serum (AS) and group II treated with preservative free artificial tears (PFAT). Follow-up evaluation were conducted at 15 days, 1 month, 2 months, and 3 months. Statistical Analysis: The results were analyzed using the Chi-square test and t-test. P<0.05 was considered statistically significant.

: After 3 months of treatment, a significant improvement was noticed in OSDI, Schirmer’s test, TBUT, and NEI Scoring in both AS and PFAT groups but improvement was found stronger in AS group as compared to PFAT group (p < 0.001).

Topical autologous serum may be an effective alternative for treatment of dry eye condition caused by drug Isotretinoin.
Choroidal thickness in type 2 diabetes mellitus patients using spectral domain optical coherence tomography
Authors: Ijeri Raghavendra K , Israel Mervin Jonathan , Sankolli Nikhita Anil
Published: September 2024

To measure the choroidal thickness in patients with type 2 diabetes mellitus and its comparison to healthy age-matched individuals.

This prospective comparative study conducted at departments of Ophthalmology, Shri B.M. Patil Medical College, Hospital and Research Centre, Vijayapura. Study included 192 patients, 96 with diabetes and 96 age-matched controls. Data acquired comprised demographics, a thorough eye examination, fundus photography and spectral domain optical coherence tomography measurements of choroidal thickness using enhanced depth imaging.

Mean age was 60.17±7.727 years with male predominance in both cases and controls. The mean duration of diabetes was 5.67±3.39 years. Positive correlation was noted between duration of diabetes and severity of retinopathy (p = 0.001). 21 patients did not have any evidence of diabetic retinopathy, while 75 patents had features of non-proliferative diabetic retinopathy, of which (31) had mild, (21) moderate, (12) severe and (11) with proliferative diabetic retinopathy. Mean choroidal thickness of controls was 327.308±18.945 microns, as compared to thinner choroids 295±15.082 microns in cases without retinopathy and 271 ± 36.122, 242 ±30.048, 193±15.748 microns in mild, moderate, severe non-proliferative diabetic retinopathy respectively and 191.492± 23.834 microns in proliferative diabetic retinopathy. Statistically significant differences were noted on comparing choroidal thickness between controls and cases (p = 0.001).

Choroidal thickness was maximum in control group with a p value of <0.001, while cases showed overall thinner choroids with increasing severity of retinopathy. Thinnest choroids were observed in patient with proliferative diabetic retinopathy. Choroidal thickness can be used as a non-invasive prognostic bio marker for diabetic retinopathy.
Role of yoga in prevention of obesity (Sthaulyata) a lifestyle disease
Authors: Gupta Brajesh , Pandey Smriti
Published: September 2024

: Srotas are the internal transport system of the body which provides assistance for the activites of significant biofactors like tridosh, seven dhatu , the oja etc. Acharya Charak described 13 srotas and Acharya Shushrut described 11 pair of Srotas. Medovahasrotas is mentioned of meda to the destination tissue i.e., the channel which supply nutrition to medodhatu is known as medovaha srotas. Each srotas have their own places of origin known as moolasthana. and are the moolasthana of medovaha srotas mentioned in ayurvedic literatures. Medovaha srotas is vitiated by different Ahar, Vihar like etc these factor cause medo dushti resulting in medovridhi/sthaulyata. WHO defined obesity as a common chronic disorder of excessive body fat. India rank among top 10 obese nations. Obesity is caused from lack of physical activity with increased intake of food. The sedentary habits, lack of exercise and various variety among daily diet. eg., fast food, frozen food, increase amount of soft drinks canned food results in obesity. Yoga is essential a spiritual discipline based on an extremely subtle science which focuses on bringing harmony between body and mind. It plays important role in management of obesity and for effective prevention of progression complication.

: The world is looking towards drugless therapies like Yoga and Naturopathy. Both are rapidly growing as the best alternative treatments. Sushruta has also mentioned the drugless therapy and quotes that the diseases may be cured by following proper diet and lifestyle without any medicine. But in the absence of proper diet and lifestyle, even after giving hundreds of medicines, the disease cant be cured. An attempt to evaluate utility of Yoga in the management of overweight and obesity has been made through this study.

: The present study is a conceptual study done in P.G. department of Kriya Sharir, State Ayurvedic college and Hospital, lucknow

: Life style modification involves altering long term habits, typically for eating or physical activity and maintaining the new behaviour. Yoga and life style modification can be used to treat a range of disease include obesity. Some Yoga and Asanas which are very helpful in reduce weight in obese persons are Trikonasana, Pawanmuktasana, Sarvangasana, Dhanurasana etc.
WHO guidelines for quality control of herbal medicines: From cultivation to consumption
Authors: Jain Sourabh D , Shrivastava Shravan Kant , Agrawal Ankit , Gupta Arun Kumar
Published: September 2024

WHO guidelines serve as a comprehensive framework for ensuring the safety, efficacy, and quality of herbal products throughout their lifecycle, from cultivation to consumption. Here's why adherence to these guidelines is crucial. By following WHO guidelines, manufacturers can implement practices that minimize the risks associated with herbal medicines, including contamination, adulteration, and variability in potency. This helps protect public health and ensures that consumers can use herbal products with confidence. Quality control measures recommended by WHO contribute to the consistency and reliability of herbal medicines.

Standardization of production processes and the establishment of quality parameters help maintain the potency and efficacy of herbal products, leading to more predictable therapeutic outcomes. Adherence to WHO guidelines facilitates compliance with regulatory requirements established by national authorities and international bodies. Regulatory agencies often refer to WHO guidelines when developing regulations for the manufacturing, distribution, and labeling of herbal medicines. Compliance with these guidelines helps manufacturers meet regulatory standards and gain market authorization for their products. WHO guidelines provide a harmonized approach to quality control practices, promoting consistency and uniformity in the assessment of herbal medicines worldwide. This facilitates international trade and ensures that products manufactured in one country meet quality standards accepted globally, fostering trust and confidence among consumers and healthcare professionals. The systematic review highlights the ongoing efforts of WHO to review and update guidelines based on emerging scientific evidence and best practices. Adhering to these evolving guidelines encourages continuous improvement in quality control practices and fosters innovation in the herbal medicine industry.
Nada por el estilo
Authors: Pérez Vidal Iván
Published: September 2024

Con textos de Iván de la Torre Amerighi, Jaime Rodríguez Alba, Dionisio Cañas y el propio Iván Pérez Vidal. Esta publicación se enmarca en el proyecto desarrollado por Iván Pérez Vidal a través de las ayudas Margarita Salas 2021. (Ministerio de Universidades. Programa Next Generation EU, Plan de recuperación, transformación y Resiliencia, Universidad de Castilla-La Mancha) y ha sido financiada con las ayudas al retorno de investigadores de la UCLM tras la estancia de investigación en el Laboratorio de creaciones Intermedia de Universidad Politécnica de Valencia.
Unique fatty acid composition of coriander seed biodiesel
Authors: Simsek Suleyman , Koç Esra , Öztürk Ayşegül
Published: September 2024

Biodiesel is a renewable and environmentally friendly alternative fuel that can be used in diesel engines without modification. In this study, biodiesel production from coriander seed oil obtained through a two-stage transesterification process using the cold pressing method was carried out in the Konya region. First, the oil's acid value was reduced through acid-catalyzed pretreatment to form coriander seed oil methyl esters, and then biodiesel was produced using standard transesterification with methanol and sodium methoxide catalyst.
Coriander (Coriandrum sativum) contains an unusual fatty acid not previously reported as a major component in biodiesel fuels: petroselinic acid (6Z-octadecenoic acid; 68.5% by weight).
Coriandrum sativum seed oil methyl ester was evaluated to have properties suitable for diesel engines, complying with EN 14214 and ASTM D6751 standards, with a unique fatty acid composition and excellent oxidative stability.
Pengaruh Jenis Kemasan pada Perubahan Kualitas Salak Pondoh Banjarnegara dalam Bentuk Tandan Selama Transportasi dan Penyimpanan
Authors: Ratik Srimurni Rafika , Yuliasih Indah , Darmawati Emmy , Muliani Yenny , Herdiana Mega
Published: September 2024

Salak (Salacca edulis Reinw.) in bunch form can be attractive to consumers because its own unique shape. The use of primary and secondary packaging can maintain fruit quality. This study aims to evaluate quality change of salak in bunches including physical damage, mechanical damage, physiological and microbiological damage. Salak bunches were stored for 22 days, with observations every 3 days to analyze fruit damage, TSS, weight loss, and fruit hardness. The study used a single-factor completely randomized design, involving 3 treatments: wooden crates (K1), cardboard without net foam (K2), and cardboard with net foam (K3). Data were analyzed descriptively, analysis of variance, and DMRT at the 5% level. Primary packaging was effective in reducing mechanical damage to fruit after 13 hours of transportation, with mechanical damage reaching 0 (zero) due to net foam. The type of packaging used had a significant effect on quality change of salak during storage, namely physical, physiological and microbiological damage, weight loss, hardness, and TSS. Cardboard packaging with net foam was the best treatment, showing low physiological and microbiological damage until the 16th day of storage, which amounted to 4.05, as well as a low rate of change in quality for 22 days.
 
Keywords: Salak bunches, storage, packaging, fruit quality, transportation