bluuebunny/crossref_metadata_2025 huggingface dataset:
Équivoques et tourments de l’utopie
Authors: Capdevila Nestor
Published: March 2022

L’histoire de l’Union soviétique a prétendu réaliser l’utopie avant d’en confirmer l’impossibilité. Le présent livre développe cette ambivalence en faisant jouer la polysémie de l’idée d’utopie (négativité, rêve, projet, illusion) et en reproduisant le conflit entre l’utopiste et l’anti-utopiste sous la forme des tourments de la conscience utopique, où la limite entre la libération et l’oppression devient énigmatique. Conceptualiser l’utopie, c’est construire un espace conflictuel de prises de position. Elle apparaît comme l’effet changeant des rencontres conjoncturelles entre des visions contradictoires du monde social et politique. Sa polarité dans l’imaginaire avec l’idéologie est le point d’articulation entre la politique et l’histoire comme processus ouvert, incertain et non totalisable. Elle existe alors sous la forme d’un travail de l’espérance, conçu comme une interprétation et une intervention dans des conjonctures jugées oppressives, même si son contenu reste indéterminé et controversé. L’incapacité où se trouve la conscience moderne de tracer une ligne de démarcation entre le possible et l’impossible, l’utopie, l’idéologie et le réel, explique qu’un concept d’utopie soit à la fois problématique et indispensable.
Le meilleur ou le vrai
Authors: Danino Philippe
Published: March 2022

Accusé par Burgh de considérer sa propre philosophie comme la meilleure de toutes, Spinoza rectifie : il sait seulement qu’est vraie celle qu’il comprend. Mais on ne trouvera chez lui ni réelle thématisation ni véritable définition de l’idée de philosophie, pas plus qu’un vaste programme de connaissances, comme s’appliquent à en dresser Bacon, Descartes ou Hobbes.

Cet ouvrage enquête alors sur la présence, chez Spinoza, d’une conception précise, voire singulière, de l’idée de philosophie. Étudier les occurrences du terme « philosophie », la nature de la définition qui en est proposée, les raisons de passer du titre pressenti de Philosophie à celui d’Éthique, voilà qui produit autant d’indices d’une idée de philosophie comme praxis de distinction ou, selon l’expression d’Althusser, comme activité de tracer des lignes de démarcation. Mais l’ouvrage établit encore que la philosophie ne prend elle-même sens qu’en ce geste, c’est-à-dire par le biais de relations nécessaires avec ce qui a priori n’est pas elle : le vulgaire, l’ignorant, le théologien, le souverain ou même d’autres philosophes. L’idée de philosophie, en d’autres termes, s’autoproduit dans un système de rencontres singulières. En analyser les fruits permet alors de recomposer la nature de la « vraie philosophie » : une pratique de production d’idées et de leur communication. Mais se fait jour, en outre, comme un naturel philosophe, un effort s’éprouvant selon une réjouissance propre au « vrai philosophe », déjà sage en vertu de son mouvement, visant son perfectionnement et l’accroissement de sa puissance.
Albert Camus, de la transfiguration
Authors: Bove Laurent
Published: March 2022

Lire Camus au-delà de la « philosophie de l’absurde » et de l’image sartrienne d’un « moraliste » tourné contre l’histoire, c’est le projet de cet ouvrage qui revisite l’œuvre en éclairant ses soubassements immanentistes et sa critique radicale de la modernité. Son fil d’Ariane est une philosophie du corps déchiffrée à travers le récit de L’Étranger et les peintures du Christ de Piero della Francesca que Camus admire. Et ce sont alors les thèmes de la résurrection du corps et de la transfiguration qui permettent d’explorer les axes les plus prospectifs des textes dans les domaines de l’éthique, de la politique et de l’histoire. Ce livre montre qu’il y a encore, pour nous, aujourd’hui, dans l’expérience singulière et l’œuvre courageuse d’Albert Camus, de quoi penser et résister.
MULTI-SCALE DIRECTED ACYCLIC GRAPH-CNN FOR AUTOMATED CLASSIFICATION OF DIABETIC RETINOPATHY FROM OCT IMAGES
Authors: Sunija A. P. , Krishna Adithya K. , Gopi Varun P. , Palanisamy P.
Published: March 2022

Diabetic Retinopathy (DR) is the principal cause of vision loss that interrupts the regular interaction of vascular, neural, and retinal constituents leading to impaired neuronal function and retinal abnormalities. Diagnosis of DR from Optical Coherence Tomography (OCT) image is difficult and time-consuming because several small features must be identified and graded, which results in a strenuous diagnosis when integrated with the complexity of the grading system. This study focuses on classifying DR from normal Spectral Domain-OCT (SD-OCT) images using the Directed Acyclic Graph (DAG) network without any pre-processing techniques. The proposed DAG-CNN model comprises 16 convolutional blocks, which learns multi-scale features automatically from multiple layers in the convolutional network and combines them effectively for the DR and normal prediction. The proposed model is tested on the public OCTID_DR and private LFH_DR SD-OCT databases containing DR and healthy OCT images. The model achieved an accuracy, precision, recall, F1-score, and AUC on OCTID_DR database of 0.9841, 0.9727, 0.9818, 0.9772, and 0.9836, respectively; and on LFH_DR database the respective values are 0.9988, 1, 0.9976, 0.9988, and 0.9988 with only 0.1569 Million of learnable parameters. This method significantly reduces the number of learnable parameters and the model’s computational complexity in terms of memory required and FLoating point OPerations (FLOPs). Guided Gradient-weighted Class Activation Mapping (Grad-CAM) is performed to highlight the regions of SD-OCT images that contribute to the decision of the classifier. Our model significantly surpasses the accuracy of the existing models with lower resource consumption and higher real-time performance.
Lauric Acid as an Energy Storage Material to Increase Distillation Solar Productivity in Indonesia
Authors: Caturwati Ni Ketut , Rosyadi Imron , Yusuf Yusvardi , Saputra Ehsan Tri
Published: March 2022

The use of energy storage materials in a solar distillation system is intended to increase condensate production by making changes in the temperature of the system change slowly, not following fluctuations in the intensity of solar radiation that can change quickly and drastically. One of the effective energy storage systems is the use of Phase Change Materials (PCMs), materials that involve a phase change process in storing and releasing heat, because the latent heat involved in the phase change process has a large enough value under constant temperature conditions so that temperature stability in the system is achieved. The choice of PCM type used in solar distillation is determined by the average temperature that can be reached by the water in the basin, which is strongly influenced by local environmental conditions. This study compares the productivity of the distillate produced by the double slope solar distillation system that uses Lauric Acid as PCM and that does not use PCM. Both studies were conducted at the same time. The optimal amount of LA that must be added to the solar distillation system to get the highest increase in condensate production value is 7.54 kg of Lauric Acid for 64.8 kg of raw water..
High Strength of Aluminium-Based Composites by Different Methods of Severe Plastic Deformation (SPD)
Authors: Pramono Agus , Zulfia Anne , Dhoska Klodian , Suryana Suryana , Milandia Anistasia , Zulaida Yeni Muriani , Juniarsih Andinnie
Published: March 2022

Composite materials were applied to meet the demands of production efficiency on industrial because they offered the superior properties both of aspects on mechanical and physical properties were constantly being refined and developed with several methods. Composite technology with aluminum as a matrix as well as ceramic materials as reinforcement was very dependent on a result of the perfection of the manufacturing process on the matrix material and reinforcement was used. Aluminum currently still dominates as a matrix because of its ductility, while reinforcing materials that are widely used are ceramic elements such as silicon carbide (SiC) and alumina (Al2O3). Using of SiC/Al2O3 has been widely studied because of the remarkable improvement of the mechanical properties it produces. The addition of number of SiC particles to Al2O3 was able to significantly increase the hardness properties. In this study, a number of composite manufacturing methods were compared from the results of properties by accumulative press bonding (APB), accumulative roll bonding (ARB), and repetitive press roll forming (RPRF). The mechanical properties of RPRF results are known to produce better properties, especially mechanical properties. Mechanical properties were observed from tensile and hardness tests. The finer grain size is produced by increasing the compression cycle and increasing the mechanical properties when adding double reinforcement of the SiC/Al2O3, which causes the strength and hardness of the RPRF results to increase. Whereas other methods such as APB and ARB it is not compatible with composite materials, this proves that the RPRF method was very suitable for processing composite materials compared to APB and ARB methods.
Effect of Thermomechanical Processing on the Microstructures and Mechanical Properties of Cu-28Zn-2Al Alloys
Authors: Basori Imam , Ponco Mahardika Sandy , Sari Yunita
Published: March 2022

This research was conducted to investigate the effect of thermomechanical process on microstructures and mechanical properties of Cu-28Zn-2Al alloys. Thermomechanical process was carried out by cold rolling process with 70% thickness reduction and followed by annealing process with variation temperature of 400°C, 500°C and 600°C. The result show that the β phase and shear bands are found in the samples. Further, cold rolling process can increase hardness of Cu-28Zn-2Al alloys from 100 to 172 VHN. The heat treatment with annealing process at 400°C tend to decrease the tensile strength of cold rolled samples from 695 to 472 MPa and more decreased until 422 MPa at 600°C. In contrast, annealing process at 400°C tend to increase the elongation from 10 to 28% and more increased up to 56% at 600°C. This phenomenon prove that the annealing process will increase ductility of cold rolled samples of Cu-28Zn-2Al alloys.
The Effect of Orientation Angle and Layer Thickness on Surface Roughness of ABS Material on FDM
Authors: Kholil Ahmad , Syaefuddin Eko Arif , Premono Agung , Nugraha Farhan
Published: March 2022

Surface roughness of ABS material on FDM process due to different orientation angle and layer thickness are investigated using an experimental method. The aim of this paper is to determine the effect of orientation angle and layer thickness on surface roughness on 3-dimension FDM printing on ABS material. A rectangle model with 60 mm length,10 mm in width, and 10 mm in height is used in this research. The orientation angle of model is 30, 45, and 60 degrees in layer thickness of 0.15 mm and 0.25 mm. The results indicates that the different orientation angle of the layer thickness causes the roughness value of the printed surface. The roughness surface value increases along with increasing of the orientation angle. The highest surface roughness value occurs at 60 degrees orientation angle in 0.15 mm layer thickness.
Synchronous gallbladder carcinoma in a patient with distal bile duct cholangiocarcinoma: a histopathological surprise
Authors: Indunil L. , Pathirana A. , Nandasena M. , De Silva G. P. U. P.
Published: March 2022

No abstract available
Epigastric hernia complicated with bowel ischaemia
Authors: Wijenayake W. , Senarath R. M. U. S. , Jayasekara J. M. S. , Divinda P. M. T.
Published: March 2022

Epigastric hernia, a form of abdominal ventral hernia, accounts for 0.5 – 10.0% of all abdominal wall hernias. These may be congenital due to incomplete midline fusion of developing lateral abdominal wall domains or acquired. It usually occurs in individuals in the age groups of 20 to 50 years and in infants. It is rarely large enough to admit more than a small amount of extra-peritoneal fat. We discuss an epigastric hernia known only for little more than 4-hours, presented strangulated, leading to ischaemia of small bowel requiring resection and review literature on epigastric hernias and their complications.
Impact of microscopic intermediate sub inguinal varicocelectomy on varicocele and infertility
Authors: Balagobi B. , Gobishangar S. , Vinojan S. , Charles J. C.
Published: March 2022

Varicocele is primarily tortuous dilation of the internal spermatic vein [ISV] and pampiniform plexus in the scrotum. It’s the most common correctable cause of infertility. It has a higher prevalence in primary and secondary infertility in men. In this article, we reviewed the advantages and disadvantages of microscopic intermediate sub inguinal [MISV] varicocelectomies over conventional surgical methods. Although various mechanisms are postulated for pathogenesis, increased venous reflux is accepted as the predominant cause. Varicocelectomy is done to ligate the veins and reduce venous reflux without affecting the arteries, vas deferens and lymphatics. Open, laparoscopic and microscopic varicocelectomies are the different surgical approaches of varicocele. Embolization is another treatment option. MISV is a relatively novel technique and considered superior to the conventional treatment approaches because of increased spontaneous pregnancy rates, reduced recurrence, increased seminal parameters and fewer postoperative complications, as evidenced by many studies. Microscopic visualization and usage of micro-doppler in surgery gives more safe and easy handling of the operative field. Absolute indications for varicocelectomy are documented infertility, clinically palpable varicocele abnormal seminal parameters and potentially treatable female infertility or normal fertility. Persistent pain, discrepancies in the testicular volume of more than 20% and hypogonadism are considered as relative indications for varicocelectomies. MISV should be regarded as the gold standard treatment method for varicocele.
Music therapy for elderly sleeping quality
Authors: Law Siukan , Au Dawn Chingtung , Leung Albert Wingnang , Xu Chuanshan
Published: March 2022

Elderly people have sleeping disorder problems which can be occurred frequently. This is a significant public health issue because sleeping disorder leads to cause depression, diabetes, cardiovascular, Alzheimer’s disease. Currently, music therapy might be a good choice instead of western medicines for the treatment of a sleeping disorder. This short communication describes the background of sleeping disorder, music therapy, and its research progress as well as the future development. A simple systematic search of publications in PubMed, Embase, Cochrane Library, and google search without language restriction is performed. Because of the little finding on the music therapy for sleep disorders in present literature, therefore, there is a short communication written by some literature reviews before starting a novel study of sleeping disorders for elderly people.
Recenti dualismi in bioetica
Authors: Fiori Angelo , Sgreccia Elio
Published: March 2022

Non disponibile
Profilo etico-giuridico delle vaccinazioni obbligatorie e facoltative
Authors: Bompiani Adriano
Published: March 2022

L'autore affronta il tema delle vaccinazioni obbligatorie e facoltative sotto il profilo etico e giuridico. In particolare, dopo aver accennato alla differenziazione fra ordine etico ed ordine giuridico, si sofferma sui seguenti aspetti: 1) analisi dei fattori etici insiti nelle decisioni dell'autorità sanitaria: obbligatorietà e volontarietà dei trattamenti vaccinali; 2) valutazione dei fattori etici che dovrebbero guidare l'atteggiamento del cittadino di fronte alla richiesta di trattamenti sanitari - volontari od obbligatori - a carattere preventivo; 3) libertà morale del genitore e del bambino; 4) caratteristiche intrinseche di liceità del trattamento (sicurezza dei risultati, innocuità del vaccino sotto il profilo tecnico, ecc.).
Medicina funzionale-psicosomatica in neonatologia
Authors: Tortorolo G.
Published: March 2022

Il neonato, in particolare quello pretermine e soprattutto per condizioni di patologia neonatale, può andare incontro oltre che a sequele da cause organiche, anche a sequele da cause funzionali. L'autore, richiamandosi nella introduzione all'esperienza della Divisione neonatologica dell'Università Cattolica di Roma, presso la quale è istituito un Corso permanente di formazione in psicoprofilassi e psicosomatica neonatologica, presenta e discute, brevemente ma in modo chiaro, la etiopatogenesi e la clinica delle turbe psicosomatiche nel neonato, nonché la loro profilassi e terapia.
Extensive calcification in genitourinary tuberculosis misdiagnosed as ureteral calculi
Authors: Singh Gurpremjit , Navriya Shiv Charan , Kumar Sunil
Published: March 2022

Ureteral calcification in genitourinary tuberculosis is extremely rare. A 36-year-old female presented with a diagnosis of right ureteral calculi. On further investigations, she was found to have a right nonfunctioning kidney with a suspected diagnosis of genitourinary tuberculosis which was confirmed on histopathology.
Membrane-organizing extension spike protein and its role as an emerging biomarker in oral squamous cell carcinoma
Authors: Bommanavar Sushma , Kanetkar Sujata R , Datkhile Kailas D , More Ashwini L
Published: March 2022

Oral squamous cell carcinoma (OSCC) is the most malignant tumor worldwide with a relatively poor prognosis. This can be due to lack of using new specific biomarkers as a mode of pristine interventional therapy for detecting the lesions at an early stage, thereby not allowing it to proceed to a severe advanced stage. Biomarkers, being the products of malignant cells, can prove to be promising prognostic factors in understanding the molecular pathogenesis of oral cancer. One such biomarker is membrane-organizing extension spike protein (MOESIN). Belonging to the family of ezrin/radixin/MOESIN proteins, MOESIN acts as a structural linker between plasma membrane and actin filament of the cell moiety and is involved in regulating many fundamental cellular processes such as cell morphology, adhesion and motility. This narrative review is a systematic compilation on MOESIN and its role as an emerging biomarker in OSCC.
Evaluation of salivary oxidative stress in oral lichen planus using malonaldehyde
Authors: Singh Shruti , Singh Jaya , Biradar Basavaprabhu C. , Sonam Manjari , Chandra Shaleen , Samadi Fahad M.
Published: March 2022

Background:

Oral lichen planus is a chronic, mucocutaneous, inflammatory disease, with an unknown etiology. Reactive oxygen species and oxidative damage to the tissues might be the cause. Malonaldehyde (MDA), a low molecular weight end product of lipid peroxidation reaction is a suitable biomarker of endogenous DNA damage. monitoring the oxidant-antioxidant status of saliva may serve as an efficient marker of disease development in oral lichen planus patients.

Aim and Objectives:

To evaluate salivary oxidative stress in oral lichen planus subject using MDA and compare it with control subjects. Furthermore, to compare MDA levels in erosive and hypertrophic lichen planus.

Materials and Methods:

The current study is case–control study. Unstimulated salivary samples in the morning hours were taken from oral lichen planus subjects (n = 25) and controls subjects without any oral disease (n = 25). The saliva was centrifuged at 900 g for 10 min at a temperature of 4°C. Then, the entire filtrate was transferred to Eppendorf test tubes and frozen at–80°C until analysis. Salivary MDA was done through thiobarbituric acid reactive substance assay as per the protocol laid down by the manufacturer (Sigma Aldrich Lipid Peroxidation Assay Kit).

Results:

The data were expressed as the mean ± standard deviation and the statistical analysis was done using Student's t-test using SPSS version 21 IBM software. The salivary level of MDA was significantly higher than that of controls (P < 0.05).

Conclusion:

The higher level of MDA in patients with oral lichen planus suggests that free radicals and the resulting oxidative damage may be important in the pathogenesis of oral lichen planus lesions.
Mandibular metastasis of follicular thyroid carcinoma
Authors: Jawanda MK , Narula R , Gupta S , Gupta P
Published: March 2022

Metastasis is one of the most common consequences of malignant tumors, and it is one of the leading causes of morbidity and mortality. Metastatic cancers to oral cavity are extremely rare. Moreover, the true incidence has yet to be determined. Despite their rarity, they are important clinically, since they can be the first and the only evidence of spread in many situations. Breast, kidney, lung, prostate and gastrointestinal tract are the most common sources of metastases in the oral cavity. Thyroid carcinoma is the most prevalent type of endocrine cancer, yet it rarely spreads to the oral cavity. After papillary thyroid carcinoma, follicular thyroid carcinoma is the second-most frequent kind of thyroid cancer. Jawbones are more commonly affected than soft tissues. Literature research revealed that till date, 44 cases of metastatic follicular thyroid cancer to the jawbones have been documented with mandibular preponderance (40 cases). With the rising occurrence of oral metastatic tumors in recent years, it has become increasingly important to diagnose them early to avoid future consequences. We present here an unusual case of metastatic follicular thyroid cancer in the mandible of an elderly adult along with a comprehensive review of the literature.
The diverse role of oral fibroblasts in normal and disease
Authors: Vijayashree R. J. , Sivapathasundharam B.
Published: March 2022

Fibroblasts are the major cellular component of the connective tissue. They differ both structurally and functionally based on their location. The oral fibroblasts vary from the dermal fibroblasts in their origin, properties and also functions. These cells play an important role in wound healing, tumor progression and metastasis, allergic reactions. In this review, the various functions of the oral fibroblasts are discussed in detail.
Ear-Related Problems among Headphone users in the Kingdom of Saudi Arabia
Authors: Aljuaid M Sattam , Althobaiti Hazem K , Alotaibi S Hamoud , Sarriyah Abdulhameed Fouad , Alsuwat Mohammed Abdullah , Alfaqih H Eyad , Almnjwami Rakan Fiasel Mohammed
Published: March 2022

Background and Objectives:

The middle ear cleft and the tympanum inflammation are defined as otitis media. The patient's use of headphones has been linked to aural hygiene issues and ear canal infections. Interestingly, there are not enough studies discussing the hazardous effects of prolonged use of headphones. This study aims to estimate the prevalence of ear infection among headphone users.

Materials and Methodology:

A cross-sectional study was conducted between February 2021 and December 2021 among 435 Saudi participants through a pretested questionnaire that was published using an online-based (electronic) form. The questionnaire included items related to pattern of hearing devices used among them and ear-related problems. This study includes all persons using earphones in the Kingdom of Saudi Arabia whose native language is Arabic.

Results:

Experiencing ear-related problems is statistically significantly correlated with ear infection (P = 0.000), using both ears (P = 0.000), female gender (P = 0.009), being a student (P = 0.003), using the hearing device >120 min/day (P = 0.015); however, it is not statistically correlated with age, type of residency, or the type of device being used (P > 0.05).

Conclusion:

Increased usage of hearing devices and prolonged time of use can have detrimental effects on ear problems. These possible effects are statistically significantly correlated with young age, female gender, being a student, using the device for more than 120 min/day, using the device for more than 4 years, or having chronic diseases in the past.
Ultrasound Features and Estimated Risk of Malignancy in Thyroid Nodules
Authors: Doubi Aseel O. , Alshammari Nouf H. , Bedaiwi Reenad Hussain , Alshdokhi Ali Mohammad , Aljomah Dana , Albosaily Ahmad , Aldhahri Saleh
Published: March 2022

Introduction:

A significant uncertainty surrounding the diagnostic accuracy of ultrasound (US) and the risk features in thyroid nodules exist to date which impacts clinical practice and guidelines. Methods: This retrospective descriptive observational study included patients with thyroid nodules with US reports over 10 years and either had a fine-needle aspiration (FNA) cytology result, a pathology report or both. Results: A total of 483 patients were included. Most of the patients were <55 years old (67.3%) and the majority of them were females (91.3%). The FNA cytology results indicated that 311 (64.4%) of the thyroid nodules were benign and 32 (6.6%) were malignant. Overall, only 181 (37.5%) of the patients had a final histopathologic assessment; of these, 80 (44.2%) had malignant thyroid nodules, 78 (43.1%) had benign nodules, and 23 (12.7%) had microcarcinoma. multivariate logistic regression analysis revealed that having US features of hypoechogenicity (adjusted odd ratio 3.37; 95% confidence interval [CI] 1.03–11.00) and a microlobulated or irregular margin (aOR 3.65; 95% [CI] 1.13–11.79) were the only sonographic characteristics that had a statistically significant association with thyroid cancer based on final pathology.

Conclusion:

Thyroid nodules showing hypoechogenic echogenicity and microlobulated or irregular margin on US need to be closely followed and given the appropriate management based on their risk criteria.
A Study of High Refinement Simulation Prediction on the CAB Development for FMVSS226 Ejection Mitigation Performance
Authors: Shan Jinhui , Xue Lele , Wang Cheng
Published: March 2022

NHTSA released the FMVSS226 Standard in 2011, and defined the requirements for ejection mitigation systems, which limit the linear travel of headform by 100mm. In China regulations, there are similar requirements starting in 2021. Therefore, on the basis of the existing airbag design, adding the rollover protection function becomes a challenge for the airbag development. During the development of the curtain airbag, the cushion design, inflator type, and the fold pattern, all have an important influence on the airbag unfolding direction, the airbag positioning time and the airbag internal pressure, and then significantly affect the occupant protection performance afterwards. In order to reduce the cost and shorten the development time, it is necessary to predict the process of cushion deployment kinematics and the internal pressure of the airbag with high refinement, and based on it to predict and evaluate the FMVSS226 ejection mitigation performance. In this paper, a set of complete simulation development process is proposed and developed with FEA simulation method. Based on the step-by-step simulation and test validation of the tank test, fabric material mechanical properties test, airbag folding test, airbag static deployment test, drop tower validation test, the high accuracy curtain airbag simulation model could be established. With this model, the airbag internal pressure and deployment shape at 1.5s and 6s were calculated. Based on the test validation at the specified target point of A4, the proper friction coefficients were obtained and validated. Then, the delicate FMVSS226 ejection mitigation simulation model was generated, afterwards the remained target points simulations were performed. According to the comparison between the calculated results and test results, the total discrepancy of the distance between head form and window glass was within 4.4%, which has high accuracy.
The Banana (Musa balbisiana Colla) Peels Flour Modulates HTR2B Receptor Expression in the Liver Diabetic Rats
Authors: Meliala Andreanyta , Narwidina Paramita , Nurrahma Herlin Ajeng , Supriyanto Irwan
Published: March 2022

Uncontrolled diabetes mellitus (DM) has been linked to depression and lipid metabolism impairment. Serotonin (5-HT) has been known to improve lipid metabolism and affect mood. The 5-Hydroxytryptophan (5-HTP) in banana peel flour (BPF) is a precursor to synthesize 5-HT in the body, which is linked to initiating liver regeneration via HTR2B receptors. The impact of 5-HTP in the diet on HTR2B receptor expression has yet to be thoroughly investigated. We aimed to elucidate the correlation between serum lipid profile and immobility time in Tail Suspension Test (TST) as depressive-like behavior and compare the expression of HTR2B receptor in healthy and diabetic rats. Male Wistar (Rattus norvegicus) rats were assigned to the control and treatment groups in a DM model with streptozotocin (60 mg/kg) injected intraperitoneally, then either fed standard diet or BPF 10% supplemented standard diet for 21 days. Immunohistochemical staining was used to examine the expression of 5-HT, HTR2B receptors. We determined that diabetic rats fed the standard diet supplemented 10% BPF group showed significantly lower concentrations of total cholesterol and triglycerides compared to diabetic rats fed a standard diet and it was positively correlated between total cholesterol and LDL with the duration of immobility time in TST. The average immunoreactivity score in diabetic rats fed 10% BPF was the highest among the other groups, indicating that the available BPF dose is sufficient for HTR2B activation, which will support the liver cell regeneration process, and should be investigated further.
In Silico Study of Haematococcus pluvialis Biomarker Compound as Supplement to Fish Bone Remodelling
Authors: Kusumawati Daniar , Widyarti Sri , Maftuch Maftuch , Rahayu Sri
Published: March 2022

This study aims to determine the docking predictions for RAR, RXR, and ROR in the bone remodeling pathway using Haematococcus, which is the highest carotenoid-producing microalgae. Furthermore, it determines the projection of using this carotenoid-producing alga in bone development. Carotenoids include provitamin A and non-provitamin A, which are predicted to replace vitamin A in bone control. It is also required in silico proof of carotenoids' function of bone remodeling control. Furthermore, molecular and visualization docking validation was conducted using PyRx and Discovery Studio Visualizer software respectively. According to binding affinity and RMSD value, each biomarker compound had particular binding sites on RARα, RARβ, RORβ, and RORγ. Astaxanthin was the only compound with binding sites on all four receptors. Through enzymatic action, provitamin A carotenoids can serve as a precursor to retinol, allowing them to act as a native RXR ligand. Therefore, the biomarker compound used in Haematococcus pluvialis can replace the role of vitamin A in the regulation of fish bones. The prediction of bone regulation in biomarker compounds through the RAR-RXR pathways inhibited osteoblast and osteclast. Otherwise, VDR-RXR pathways regulated osteoclast maturation and osteoblast mineralization.
Allometric Model, Aboveground Biomass and Carbon Sequestration of Natural Regeneration of Avicennia lanata (Ridley). at in-active Pond of Muna Regency, Southeast Sulawesi
Authors: Hasidu Fajar , Prasetya Arif , Maharani Maharani , Syaiful Muhammad , Analuddin Kangkuso
Published: March 2022

This study aimed to establish an allometric model for estimation of aboveground biomass, and carbon sequestration in A. lanata mangrove forest growing in Muna Regency, Southeast Sulawesi. Research methods were done by transect and 5 quadrats with size of 100 m2 each. A total of thirteen individual trees with different sizes were harvested. While DBH and D30 were measured. The samples were separated into stems, branches, and leaves and then weighted. The sample from each fresh organs were taken and brought to the Laboratory and then oven dried at 80°C for 7 days. The allometric equations were established by using independent variables (DBH and D30), and dependent variables (Ws, Wb, Wl). The partial and  overall aboveground biomasses were calculated from allometric model, while carbon stock and CO2 sequestration were estimated. The results showed that the independent variable of DBH was more applicable for estimation of Ws, Wb, Wl, and total biomasses (Mg ha-1) of A. lanata forest, which were estimated as 28.28±3.48, 6.40±0.79, 5.00±0.66, and 40.08±4.97 respectively. The carbon stock in stems (13.24±1.63 Mg ha-1) was higher than in branches (3.01±0.37 Mg C ha-1) as well as in leaves (2.35±0.31 Mg C ha-1). The total of carbon stock were estimated at about 18.83±2.33 Mg C ha-1. Meanwhile, the total of CO2 absorption by A. lanata mangrove was 43.95±5.45 Mg CO2 ha-1. Therefore a regenerated A. lanata mangrove in this in-active pond area had potentiality on carbon stock and sequestrations, although these vegetation condition was still in the growth stage.
Synchrone Betrachtung mehrsprachiger geografischer Namen des Sprachenpaares Deutsch-Slowenisch anhand digitaler Texte und Diskurse
Authors: Krevs Birk Uršula
Published: March 2022

Im Beitrag wird das Vorkommen ausgewählter zweisprachiger deutsch-slowenischer Toponymika in digitalen Texten und Diskursen aufgegriffen, um die aktuelle Medialisierung historisch gewachsener deutsch-slowenischer toponymischer Zweisprachigkeit exemplarisch zu erfassen. Da bei der Einteilung der Namenpaare für dieselbe geografische Gegebenheit vordergründig der geschlossene Sprachraum entscheidend ist, folgen die exemplarischen Darstellungen den einzelnen Namenpaartypen und deren sozio- und diskursivlinguistischen Charakteristika. Für Namenpaare, die im zusammenhängenden deutschen Sprachraum (sln. Dunaj – dt. Wien), im slowenischen Sprachraum (sln. Ljubljana – dt. Laibach), in deutsch-slowenischen gemischtsprachigen Gebieten, die insular (sln. Stare Žage – dt. Altsag in der Gottschee) oder in Sprachkontaktregionen (sln. Železna Kapla – dt. Bad Eisenkappel in Kärnten, auch in der Steiermark) vorkommen, werden jeweils zwei digitale, online zugängliche Texte präsentiert, die diese Namenpaare im digitalen Format distribuieren und aus synchroner Sicht zur diskursiven Dynamik der slowenischen und deutschen zweisprachigen Toponymik beitragen.
Lexikologie
Authors: Putterer Elisabeth
Published: March 2022

Die vom Narr Francke Attempto Verlag herausgegebene Reihe LinguS (Linguistik und Schule) zeichnet sich dadurch aus, dass die Bänder nicht nur ein Grundlagenwissen in verschiedenen Bereichen der Sprachwissenschaft vermitteln, sondern dieses Wissen aus einer sprachdidaktischen Perspektive mit Bezug auf die Unterrichtspraxis behandeln. Die Publikation von Christine Römer und Afra Sturm – der 9. Band der Reihe LinguS  – bietet einen Überblick über die Grundbegriffe der Lexikologie, in dessen Mittelpunkt dementsprechend der Wortschatz und die Wortschatzvermittlung in der Schule stehen. Die Autorinnen charakterisieren ihr Buch als „eine Hilfe für das angemessene Beschreiben, Lernen und Lehren des deutschen Wortschatzes“ (S. 9).
Themendynamiken digitaler Diskurse
Authors: Kralj Saša , Polajnar Janja
Published: March 2022

Im Beitrag wird mittels eines qualitativ-quantitativen Zugangs zu deutschsprachigen und slowenischen Kommentarforen gezeigt, wie Themendynamiken diskurslinguistisch in kontrastiver Perspektive untersucht werden können. Während mit qualitativer Analyse Teilthemen samt Themenkonstituenten im Hinblick auf Akteurinnen und Akteure je Sprache erarbeitet werden, schafft die quantitative Analyse und Visualisierung frequenter Themenkonstituenten mit AntConc eine gute Vergleichsbasis für die Exploration einzelner Teilthemen sowie Themendynamiken im Diskursverlauf und sprachübergreifend in unterschiedlichen Sprachkorpora. Durch den Vergleich werden Konvergenzen (gemeinsame Teilthemen) und Divergenzen erarbeitet: Zum einen lassen sich kulturell begründete Unterschiede auf thematischer Ebene aufzeigen, die den Umfang und die Entfaltung der behandelten Teilthemen betreffen, zum anderen wird die Dialogizität auf struktureller Ebene untersucht. Insgesamt zeigt sich, dass Kommentarforen als eigenständiges Diskursmedium mit eigenen Themenentwicklungen auch in sprachübergreifender Perspektive eine wichtige Rolle bei der Wissenskonstruk­tion spielen.
Impact Analysis of Academic Guidance and Training Soft Skill to Improve Student's Self-Concept and Independence Through Tuweb
Authors: Widuroyekti Barokah , ‪Dian Ratu Ayu Uswatun Khasanah  , Binti Isrofin  , Jahyu Hartanti  , Dwikoranto Dwikoranto
Published: March 2022

The implementation of learning activities during the pandemic is carried out online, including learning activities at the Distance Learning Program Unit of the Open University of Semarang using Web-based Tutorials (Tuweb) using Microsoft Team. Online learning requires students to study independently. The purpose of this study was to integrate the impact of user experience, academic self-concept and adversity quetion on independent learning in students. This type of research is quantitative research. Data collection techniques using a psychological scale. The psychological scale used in this study is (1) the learning independence scale. (2) academic self-concept scale (3) adversity quotient scale and (4) user experience scale. The measurement results show a TLI of 0.955. This output shows the accuracy, consistency of the accuracy of the composite reliability measuring instrument which shows the accuracy, consistency of the accuracy of a measuring instrument in making measurements. Student independence is influenced by academic self-concept and user experience, but the adversity quotient does not have a significant effect.
Using Toulmin's Argument Pattern on Problem Solving Model to Improve Problem-Solving Analysis Ability: Learning Alternatives During the Covid-19 Pandemic
Authors: Dwikoranto Dwikoranto
Published: March 2022

The lecture process even in the Covid-19 pandemic must continue. The right of students to obtain good teaching must still be fulfilled. Lectures are conducted online using the Zoom, WhatsApp, Google Drive, Google Form platforms. The platform is assembled in a problem solving model with Toulmin's Argument Pattern. Problem solving analytical skills are the main focus of the Statistics course. This study aims to improve students' analytical problem solving skills, describe their improvement and describe student responses with Toulmin's Argument Pattern in problem solving models. The research design used a one group pre-test and post-test design. The research subjects were 30 students of the Unesa Physics Department. The instruments used in collecting data include: (1) problem solving analysis ability test sheets, (2) student response questionnaires. The research data scores that have been collected after going through a series of prerequisite tests, normality tests and homogeneity tests are then analyzed using paired t-tests to find out if there are differences in pre-test scores and post-test scores for solving analytical skills. student problems. The mean level of improvement in pre-test scores and post-test scores was calculated using normalized gain. The results showed an increase in problem-solving analytical skills in the medium and high categories. Student responses in lectures were very positive.
Drug Eruptions with Cases: Fixed Drug Eruption and DRESS Syndrome
Authors: AKYÖN Şeyma Handan , GENÇ Yeşer
Published: March 2022

Cutaneous drug reactions usually occur with mild and self-limiting lesions, but severe forms can be life-threatening. Non-steroidal anti-inflammatory drugs, antibiotics, and anticonvulsants often cause drug reactions. Herein, we presented two cases of immunological drug reaction, one with mild and localized fixed drug eruption and the other with more severe and diffuse DRESS syndrome.
Exergaming to Improve Balance and Decrease the Risk of Falling in Adults with Knee Osteoarthritis: A Mixed-Methods Feasibility Study
Authors: Manlapaz Donald G. , Sole Gisela , Jayakaran Prasath , Chapple Cathy
Published: March 2022

Aim: To investigate the feasibility and acceptability of exergaming using Nintendo Wii Fit™ to improve balance and reduce the risk of falls in individuals with knee osteoarthritis (OA).
Methods: A mixed-methods, explanatory sequential study design was utilized in this study. Participants with knee OA and a history of falling participated in a 16-week single-group pre-post experimental study design (eight weeks of usual care and exergaming program). This was followed by semi-structured focus groups to ask about the feasibility and acceptability of the study.
Results: The pre-defined feasibility criteria such as recruitment, retention (83%), and compliance (78%) were successfully met. This was affirmed by the participant's views on the procedures of the study in terms of the frequency and duration of the assessment and intervention sessions, which they reported to be acceptable. The study demonstrated that it is safe to use Nintendo Wii Fit™ as an exergaming tool as no adverse events were reported. Participants enjoyed playing Wii Fit™ games and found exergaming motivating and interactive despite some barriers to using technology.
Conclusion and Implications: The study appears feasible and safe, with some modifications that need to be considered in future research. Given the findings of this study, future research should employ a similar rigorous study design. The potential of this technology for helping to motivate and challenge participants to increase adherence to exercise could ultimately result in better outcomes and self-management of the condition.
Assessing Telerehabilitation Readiness among Older Adults with Hypertension in Communities in Rizal and Laguna: A Cross-Sectional Analytic Study
Authors: Callejo-Tiuseco Archelle Jane , Rimando Christian Rey , Sosa Ken Erbvin , Bergonio Yalena Mikaela , Sy Michelle Audrey Cordero , Crespo Carlos Angelo , Lim Hannah , Mallari Lorenzo Joel , Santos Crissy Jane , Sto. Domingo Fernando Levy , Zabarte Shermarie Klein
Published: March 2022

Aim: To determine acceptance of telerehabilitation, accessibility to technological resources, and technical literacy, and determine the relationship between mentioned variables among older adults with hypertension.
Methods: This cross-sectional analytic study collected data through an online survey using the Web-Based Patient-Reported Outcomes Capture System-Needs, Acceptance, and Readiness Assessments questionnaire. Purposive sampling was used through the assistance of partner communities from UST Simbahayan. Relationships between independent (socio-demographics and readiness) and dependent variables (acceptance) were analyzed through robust regression (p-value<0.0001) using STATA.
Results: Most older adults (n = 174) were female and had secondary schooling. The overall acceptance of telerehabilitation was measured through a 4-point Likert scale (Mean = 3.42; Median = 3.57). In terms of readiness, the majority have computer access and internet access at home but have a frequency of use of less than a month. Younger age increased acceptance by 0.48%, while a college graduate increased acceptance by 13%. Living in Laguna and Rizal also increased acceptance by 13% and 26%, respectively. In contrast with past studies, this research revealed that frequency of ICT use and Internet access are not predictive of acceptance of telerehabilitation.
Conclusion and Implications: Younger age, higher educational attainment, place of residence, and computer access at home were predictive of acceptance of telerehabilitation. The results suggest the need to include other quantitative aspects of telerehabilitation readiness. The findings of the study may aid in identifying the readiness of other communities in receiving telerehabilitation and addressing the barriers to implementing telerehabilitation.
Evaluation of an Arnis-Based Exercise Program for Community-Dwelling Older Adults in the Philippines: An Exploratory Study
Authors: Barlis Jason , Lipardo Donald S. , Añonuevo Diane Ernabel , Chang Eimee Jealyne , Ferrer Sophia Anne , Lama Juean Joloue , Rivera Danielle Koleen , Saludo Kristopher , Turiano Marie Therese , Porto Jerome A. , Laxa Robinson
Published: March 2022

Aim: Arnis is the national martial art of the Philippines. Similar to Tai Chi, a martial art with established therapeutic effects, it can improve the balance control of older adults. However, there has been no study conducted to prove this. This study aimed to design and evaluate an Arnis-based exercise program to improve the static and dynamic balance control of community-dwelling Filipino older adults.
Methods: A qualitative exploratory study using the Delphi Method was conducted. A 12-week moderate-intensity Arnis-based exercise program for older adults was designed. A Physical Therapist, Geriatrician, Sports Scientist, Arnis Expert, and Senior Citizen separately evaluated the video-recorded exercise program. Semi-structured interviews were individually completed online to gather their feedback. Three researchers completed the thematic analysis.
Results: Four themes represented the evaluation of the Arnis-based exercise program: Program presentation, Participant consideration, Program aspects, and safety provisions. After one round of interviews, a strong consensus was reached based on the program's appropriateness, difficulty level, benefits, and feasibility for older adults. However, the exercise program needs to be revised to improve on the aspects of safety, instructions, structure, and progression.
Conclusion and Implications: The resource persons recommend the Arnis-based exercise program as an appropriate and feasible intervention to improve the static and dynamic balance control of older adults. However, the second round of interviews is recommended to evaluate further the revised program. More studies also are necessary to establish the actual effect of this Arnis-based exercise program using experimental design.
Utilization of Smart Insole Technology in Gait Analysis: Towards Potential Gait Risks
Authors: Galagate Mary Rose G. , Guillermo Renzo Louizz T. , Maritana Anne Gwyneth B. , Velasquez Jan Meera A. , Batar Jose Angelo G. , Petil Er. D.
Published: March 2022

Aim: To identify the inter-rater reliability of a Sensory Insole technology for gait analysis (SIT).
Method: The study utilized the quasi-experimental research design with sixty respondents obtained through purposive convenient sampling. The researcher utilized Slovin's formula to determine sample size. Intra Class Coefficient (ICC) was used to determine the reliability of the tool and Cronbach’s Alpha was used to determine internal consistency
Result: The SIT had excellent reliability when assessing foot flat (ICC=0.94), push-off (ICC=0.94), swing phase (ICC=0.917); and good reliability when measuring loading phase (ICC=0.84). For internal consistency, the SIT showed high reliability when assessing for loading phase (Cronbach’s alpha=0.84), foot flat (Cronbach’s alpha=0.945), push off (Cronbach’s alpha=0.94), and swing phase (Cronbach’s alpha=0.92).
Conclusion and Recommendations: The study indicates that SIT was a reliable tool in gait analysis and can be an alternative tool in such measurements. This can help clinicians provide objective findings in the gait assessment.