bluuebunny/crossref_metadata_2025 huggingface dataset:
A correção monetária e os juros de mora aplicáveis aos créditos trabalhistas: uma análise crítica da jurisprudência do Supremo Tribunal Federal e da lei n. 14.905/2024
Authors: Xavier Beatriz Rêgo , Barbosa Guilherme Bezerra , Bruxel Charles da Costa
Published: January 2025

O presente trabalho tem como objetivo a análise crítica da jurisprudência do Supremo Tribunal Federal (STF), quanto à sistemática de atualização dos créditos trabalhistas, e da recente Lei n. 14.905/2024, que trouxe novo regramento à matéria. A pesquisa podeser classificada como qualitativa e documental, enquadrando-se, predominantemente, como um estudo de caso. Por meio da análise dos precedentes do STF, a presente pesquisa levou à conclusão de que a atual sistemática determinada pelo STF éinconsistente com os próprios parâmetros que nortearam a evolução da jurisprudência do Tribunal, assim como é inconsistente com as normas trabalhistas e constitucionais aplicáveis ao caso. A pesquisa também concluiu que a solução adotada pela Lei n.14.905/2024 é aplicável ao crédito trabalhista e corrige, ainda que parcialmente, as distorções ocasionadas pelos parâmetros fixados pelo STF nas ADC´s 58 e 59 e nas ADI´s 5867 e 6021.
Reflexões iniciais quanto ao uso da biometria nas relações de trabalho: do paradigma português às projeções no Brasil
Authors: Oliveira Neto Célio Pereira
Published: January 2025

Partindo da mais estruturada cultura portuguesa na tutela dos direitos fundamentais à proteção de dados no campo das relações de trabalho, e eleito como tema o uso da biometria para efeito de ingresso nas organizações, controle de assiduidade e dejornada, colhem-se experiências legislativas, doutrinárias e da Comissão Nacional de Proteção de Dados, projetando cenários para o Brasil, onde embora a biometria seja bastante utilizada, inexiste uma percepção do alcance dessa tecnologia e de seus efeitos,nem orientações concretas no campo das relações de trabalho, valendo-se de recente Nota Técnica da Autoridade Nacional de Proteção de Dados, que pode servir de parâmetro em que pese não relacionada às relações de trabalho.
Desenvolvimento e políticas públicas como instrumentos de liberdade: uma análise do pensamento de Amartya Sen
Authors: Arruda Kátia Magalhães
Published: January 2025

Esse trabalho pretende analisar a relação entre desenvolvimento e liberdade, tendo como referência os estudos de Amartya Sen, cujo pensamento tem se destacado por entender as privações materiais como restrições do direito fundamental à liberdade.O marco teórico é a obra “Desenvolvimento como liberdade”, com destaque para os temas da pobreza, da participação das mulheres como agentes de mudanças e do papel das políticas públicas na expansão das capacidades humanas e qualidade devida das pessoas. Para tanto, sem pretender uma incursão nas diversas teorias de justiça, pretende-se demonstrar, no pensamento do autor citado, como a opção por um critério de justiça desemboca na escolha das políticas públicas a seremimplementadas.
O caso Uber nas cortes trabalhistas do Brasil e seus reflexos na curva de Laffer
Authors: Oliveira Magno Gomes de , Oliveira Sylvianne Fontenelle Santos de
Published: January 2025

O presente estudo versa sobre o “Caso Uber no Brasil”, assim entendido como a Ação Civil Pública nº 1001379-33.2021.5.02.0004, em curso pelo juízo da 4ª Vara do Trabalho de São Paulo, que resultou em condenação da empresa Uber, em 14 de setembro de2023, a realizar a contratação de todos os motoristas ativos em sua plataforma, além de pagar R$1.000.000.000,00 (um bilhão de reais) em danos morais coletivos, tudo sem prejuízo da obrigação de que a empresa reconheça o vínculo empregatício de todos osmotoristas do aplicativo e formalize o registro dos mesmos em CTPS, sob pena de multa de R$10.000,00 (dez mil reais), por cada trabalhador não registrado3. O estudo apresentará reflexões sobre tal sentença à luz da jurisprudência atualmente dominanteno âmbito do Tribunal Superior do Trabalho, sobre os impactos econômicos da decisão em confronto com o percentual de desempregados no mercado brasileiro, e sobre seu cotejo com a “Curva de Laffer”.
Kontestasi Ketahanan Lembaga Keuangan Mikro Syariah Berbasis Sosioideologis
Authors: Muh Izza  , Mokhammad Khafidzin Fahmi  , Amalina Istikomah  , Ayu Diah Widiana
Published: January 2025

Tulisan ini bertujuan mengklaji ketahanan Lembaga Keuangan Mikro Syariah yang selama ini menjadi sorotan karena lahir dari keinginan masyarakat bawah. Ketahanan lembaga keuangan tidak selalu hanya berasal dari rasinalitas sisi finansial saja seperti fenomena LDR, NPL dan sejenisnya bahkan memiliki keterkaitan dengan aspek lain seperti kondisi social dan ideologisnya. Hal seperti ini lepas dari sorotan para akademisi dan praktisi bahkan media sekalipun. Jenis penelitian ini adalah field research dengan pendekatan basis sosioideologis. Metode pengumpulan data memakai dokumentasi, wawancara dan sejumlah instrument melalui gform pada 10 LKMS di Kabupaten dan Kota Pekalongan Jawa Tengah. Hasil riset menunjukkan ada dua corak kelembagan LKMS yaitu  1) LKMS bercorak Baitul Mal wa Tamwil melalui pengelolaan dana social dan LKMS bercorak afiliasi keormasan melalui branding religuitas produk. Ketahanan LKMS berangkat dari 8 kriteria yaitu 1) adaptasi teknologi, 2) inovasi produk, 3) peran sosial, 4) investasi  5) kepercayaan masyarakat, 6) pemasaran produk, 7) kolaborasi kelembagaan dan 8) pengalama  keuangan Kontestasi pola ketahanan LKMS berbasis sosioideologis berorentasi pada tiga aspek yaitu orentasi ketahanan normative mencakup stabilitas keuangan, orentasi ketahanan ideologis melalui keseimbangan antara nilai-nilai syariah dan kebutuhan pasar seperti inivasi produk religius, pemasaran, investasi, dan orentasi ketahanan sosiologis melalui keseimbangan antara adaptasi teknologi, pelaksanaan CSR, dan kepercayaan
Nanocomposite patches for transdermal drug delivery: A review
Authors: Singpanna Kanokwan , Pornpitchanarong Chaiyakarn , Patrojanasophon Prasopchai
Published: January 2025

Transdermal drug delivery encounters limitations due to skin’s barrier resistance, which restricts drug penetration. Only small, lipophilic drugs can easily cross the skin, limiting the range of deliverable compounds. Variability in skin thickness and condition further affects drug absorption and efficacy. In addition, potential skin irritation or allergic reactions present safety concerns. Overcoming these barriers requires advanced formulations and technologies to enhance drug delivery efficiency and safety. Recent advancements in transdermal drug delivery have led to the development of nanocomposite systems that integrate biocompatible polymers with nanoparticles (NPs) to optimize drug transport across the skin barrier. These nanocomposites offer controlled release kinetics, ensuring sustained therapeutic drug levels while minimizing systemic side effects. By enhancing skin permeability and overcoming challenges such as poor drug solubility and inconsistent absorption rates, they enable effective delivery of both hydrophobic and hydrophilic drugs. The versatility of nanocomposites allows for precise customization of drug release profiles, tailored to specific therapeutic needs and patient requirements. This technology shows promise in improving patient compliance and therapeutic outcomes, offering a viable alternative to conventional drug delivery methods. Ongoing research focuses on refining nanocomposite formulations to enhance efficacy, scalability, and regulatory approval, aiming to expand their clinical applications across various medical fields. This review article provides a comprehensive overview of NPs widely used in transdermal delivery, including lipid-based, polymeric-based, and inorganic NPs. It also discusses types of transdermal patches, such as reservoir, matrix, drug-in-adhesive, and hydrogel patches. In addition, biomedical applications, limitations and future perspectives are thoroughly addressed.
Elimination of polycyclic aromatic hydrocarbons in light cycle oil via hydrogenation over NiMo-based catalysts
Authors: Sangjun Peeranat , Nuangjumnong Sippawich , Hunsiri Warodom , Hongkailers Surachet , Hinchiranan Napida
Published: January 2025

Light cycle oil (LCO) is a by-product obtained from the fluid catalytic cracking unit in petroleum refineries. Since LCO has a high content of organosulfurous compounds and polycyclic aromatic hydrocarbons (PAHs), which adversely affect the environment and animals, LCO cannot be directly applied in combustion engines. To utilize LCO as a higher value-added chemical, this work aimed to transform the PAHs in LCO into aromatics with a lower toxicity, such as BTX (benzene, toluene, and xylene), tetralins, and decalins, via hydrogenation over nickel (Ni)–molybdenum (Mo)-based catalysts. The effect of the catalyst’s support on the hydrogenation efficiency was investigated using -alumina ( -Al2O3), KIT-6, and -zeolite. The results showed that the NiMo/KIT-6 catalyst exhibited the highest ability for hydrogenation of PAHs (49.6% removal of PAHs) and produced alkylbenzenes, decalins, and tetralins at 12.0, 0.22, and 36.4% selectivity, respectively, when the reaction was conducted under 40 bar hydrogen pressure at 350 C for 3 h with a stirring rate of 300 rpm. This study proposed an alternative way to produce value-added chemicals from a by-product stream derived from the petroleum refinery process, thereby expanding the options for sustainable development.
Two-stage stochastic optimization of sustainable bioethanol supply chain based on demand uncertainty and seasonal availability of biomass
Authors: Fahrullazi Fahrullazi , Siemanond Kitipat
Published: January 2025

Bioethanol-blended gasoline fuel is one of the alternatives for reducing CO2 emissions in the transportation sector. Since its production is still dependent on demand fluctuations and feedstock availability, an optimal supply chain design needs to be evaluated. A two-stage stochastic optimization model with mixed-integer linear programming (MILP) was developed for designing the optimal bioethanol supply chain under the constraints of multi-feedstock second-generation biomass based on seasonal availability and demand uncertainty. Two optimization models were implemented. The goal of the first model was to maximize the expected profits of the supply chain based on the optimal combination of biomass type, plant location and biomass-bioethanol pathways. The second extension model focused on maximizing expected profits of the supply chain with the least amount of impact on the environment via the reduction of net emission to result in an optimal supply chain. The validation process was then performed by comparing the stochastic and deterministic models in terms of plant location and operating decisions. The first model was applied to actual data of a Thailand case study involving 26 existing plants and agricultural residue availability. The optimization result illustrates that the stochastic model is 16% more profitable than the deterministic model for all random data sets. Furthermore, the extension model shows that carbon credit can contribute to around 5% of the total profit earned. Thus, the proposed models can address demand uncertainty in supply chain design and can be implemented by policymakers to achieve sustainable bioethanol production.
Improved ultra-short-term pulse rate variability using hair detection and majority vote in subintervals
Authors: Sunkom Panupong , Worasawate Denchai , Srisurangkul Chadchai , Nakayama Minoru
Published: January 2025

Remote photoplethysmography (rPPG) is a non-contact method for extracting pulse signal from a region of interest (ROI) in a human facial video. This technique enables researchers to remotely measure both heart rate and pulse rate variability (PRV). However, when the forehead is used as the ROI for rPPG signal extraction, hair can obscure parts of the skin, and changes in ambient lighting may introduce spurious frequency spikes, which degrade the rPPG signal and PRV accuracy. This paper proposed a method to improve ultra-short-term PRV derived from the rPPG signal using the forehead ROI. The approach incorporated a hair detection algorithm to extract the rPPG signal from skin areas, excluding regions covered by hair. In addition, a majority voting mechanism was applied to subintervals to determine the optimal passband frequency for a bandpass filter, effectively eliminating spurious frequencies. The ultra-short-term PRV was then computed from the refined rPPG signal. Results show that the mean absolute error of the ultra-short-term PRV was improved for most subjects compared to the mean absolute error obtained via the conventional method.
Comparison of stress distribution on articular disc between the Hunsuck/Epker and NM-Low Z plasty technique for mandibular setback procedure
Authors: Sakyanun Chutiwat , Chaiprakit Narissaporn , Inglam Samroeng , Patchanee Siripatra
Published: January 2025

Novel modification of Low Z plasty (NM-Low Z) technique is a bilateral sagittal split osteotomy (BSSO) technique in which the incision line is designed to create more inferior support at the proximal segment compared to the Hunsuck/Epker (HE) modification. This study aimed to evaluate and compare the stress distribution patterns at the articular disc of the temporomandibular joint (TMJ) using the NM-Low Z technique and HE modification in mandibular prognathism models. Finite element models of the mandible including the TMJ from a CT scan of a patient with skeletal class III deformity that required mandibular setback surgery, were segmented using the NM-Low Z and HE modification techniques. The mandible was moved 7 mm posteriorly and fixed with 2.0 mm miniplates and screws. The material properties of the articular discs were simulated as homogenous, isotropic, and linear elastic materials. Finite element analysis was used to evaluate the equivalent von Mises stress on the articular disc of the TMJ. Various muscular and biting forces were applied to simulate 1, 3, and 12 months postoperatively in both models. The maximum von Mises stresses of the articular disc in the NM-Low Z model were 60.64, 36.43, and 76.38 MPa, while those of the HE modification model were 73.40, 29.94, and 82.51 MPa at 1, 3, and 12 months, respectively. Both techniques resulted in normal stress distribution patterns on the articular disc surface. In conclusion, the NM-Low Z technique is an option for BSSO in terms of providing a lower maximum von Mises stress at the articular disc than the HE modification technique, while also providing a normal stress distribution pattern similar to the HE modification technique.
Development of mangiferin-loaded anisotropic emulsion for cosmetic applications: A comprehensive study on formulation, antioxidant activity, stability, and skin compatibility
Authors: Sobharaksha Parapat , Mahamongkol Hansa , Channarong Sunee , Tansathien Kritsanaporn , Wongtrakul Paveena
Published: January 2025

Liquid crystal (LC) emulsions offer a promising system for topical application due to their ability to enhance skin penetration and to improve skin hydration. Mangiferin, a natural polyphenolic compound found in mango leaves, possesses numerous therapeutic properties, including antioxidant and anti-inflammatory effects. This research aimed to develop mangiferin-loaded LC emulsions, focusing on optimizing the formulation, evaluating antioxidation activity, conducting stability tests, and examining skin compatibility. The antioxidant activity was investigated of mangiferin in an aqueous solution and in the developed emulsion against the free radical, 2,2′-diphenyl-2-picrylhydrazyl (DPPH). The developed emulsions containing sorbitan palmitate and sucrose palmitate with a 4:1 ratio displayed an obvious Maltese cross image when observed under polarized light microscopy. The stability results of the developed emulsion containing mangiferin showed that although the mangiferin content, as analyzed by UV absorption, gradually decreased over 90-day study period, its scavenging activity against DPPH radicals remained consistent throughout the study. Furthermore, the mangiferin-loaded emulsion enhanced skin health by increasing water content and reducing transepidermal water loss, without causing any skin irritation.
Development of lutein-loaded niosomes for topical delivery
Authors: Sisavengsouk Southamany , Charoenying Thapakorn , Opanasopit Praneet , Pengnam Supusson
Published: January 2025

Lutein (Lut), a fat-soluble xanthophyll compound, is a derivative of carotenoids. It has several biological activities such as antioxidant, antimicrobial, and anti-inflammatory. In particular, the antioxidant activities of Lut are widely used as primary skin protection to alleviate oxidative injury caused by free radicals from sunlight. However, the structure of Lut is easy to decompose and is unstable to exposure by various stimuli such as pH, temperature, oxidation reaction, and light. Therefore, this study aimed to formulate niosomes to encapsulate Lut. Niosomes were prepared using the thin film hydration method. The droplet size, polydispersity index, zeta potential, encapsulation efficiency, and loading capacity were investigated. Moreover, photodegradation, the effect of limonene as a skin enhancer on skin permeation, and antioxidant activity were examined. The results revealed that the niosome formulation for Lut delivery contained Span20, cholesterol, and oleic acid at the ratio of 2:1:1. The niosomes with limonene exhibited the highest skin penetration compared to the niosomes without limonene and Lut suspension. The formulation with and without limonene as a component exhibited the highest antioxidant activity. In conclusion, encapsulating Lut in niosomes could facilitate its penetration into the skin as well as enhance antioxidant properties, which can be applied and further developed into cosmeceuticals.
Impact of travel and recreational activities on stress, happiness, and life satisfaction among university students
Authors: Baroi Bijon
Published: January 2025

Continuous effort in regular activities depletes resources, leading to fatigue and negative impacts on well-being. In contrast, travel and recreational activities can promote and sustain well-being by providing adequate recovery from these stressors. In the study, thirty-five graduate students participated, selected through purposive sampling. A pre-test-post-test design with a control group was used for the study. The study aimed to assess the effectiveness of participation in travel and recreational activities in reducing stress and enhancing happiness and life satisfaction among university students. The results revealed that stress levels significantly decreased for participants engaging in travel and recreational activity, while happiness and life satisfaction increased. In addition, significant differences were found in post-test scores of outcome variables between groups, even after controlling for pretest scores. The findings suggest that sufficient recovery from the demand of adulthood through travel and leisure activities contributes to well-being. These benefits could enhance student welfare and support the growth of other institutions by promoting healthier adults.
XORAZMLIK SHOIRALAR IJODIDA DARAXT OBRAZI TALQINI
Authors: Atajanova Nilufar
Published: January 2025

This articlе discussеs thе rеprеsеntation of thе imagе of trееs in thе works of Khorеzmian poеts. In particular, thе skill of crеating imagеs of Ullibibi Otayеva and Gavhar Ibodullayеva is highlightеd through poеtic analysis.
O BURNOUT COMO DOENÇA OCUPACIONAL NA MEDICINA: ABORDAGENS INTERDISCIPLINARES PARA MITIGAÇÃO E RECUPERAÇÃO
Authors: Moura João Sérgio de Sousa , Braga João Victor Venancio , fontes Natan Oliveira , Garcia Gustavo Gonçalves , Oliveira Plínio Rocha , Farias Victor Matheus Gonçalves Muniz de , Muniz Lucas Gabriel dos Santos , Santos Gustavo Araújo dos , Furtado Carolina Diniz , Lavor Lanniel Carvalho Leite de , Almendra Camila Marques , Santos João Pedro da Rocha , Leal José Natan Moura Portela , Barbosa Marcela Marques , Kouman Kobenan Stephane Jean Charles
Published: January 2025

O burnout é um fenômeno psicológico caracterizado pelo esgotamento físico, emocional e mental, frequentemente resultante de estresse crônico no ambiente de trabalho. O impacto do burnout na medicina vai além do indivíduo afetado, estendendo-se para a qualidade do atendimento ao paciente. Diante desse cenário, o objetivo geral deste estudo é analisar as estratégias interdisciplinares de prevenção e recuperação do burnout entre médicos. A pesquisa é fundamentada em uma revisão abrangente da literatura existente, para a coleta dos dados, foi utilizada a base de dados PubMed e Scielo, A pesquisa foi conduzida com os termos "Burnout”, “Medicina”, e “Estresse Ocupacional", aplicando o operador booleano "AND". Conclui-se que a o burnout é uma condição crescente entre os profissionais de saúde, especialmente médicos, devido à alta pressão, longas jornadas e exigências emocionais intrínsecas à profissão. A revisão das evidências revela que o burnout não afeta apenas a saúde dos médicos, mas também compromete a qualidade do atendimento ao paciente, resultando em falhas no cuidado, aumento de erros médicos e maior rotatividade de profissionais. Para mitigar esse problema, é essencial implementar estratégias que integrem apoio psicológico, mudanças organizacionais e políticas institucionais voltadas para a saúde mental dos profissionais da saúde. Tais abordagens podem contribuir significativamente para reduzir os níveis de burnout e melhorar o ambiente de trabalho. Por fim, as abordagens interdisciplinares se destacam como a solução mais eficaz para lidar com o burnout na medicina. A implementação de programas de prevenção e recuperação, que considerem tanto o apoio psicológico quanto a reestruturação do ambiente organizacional, é crucial para enfrentar a síndrome de forma holística. A promoção de uma cultura de apoio e bem-estar no ambiente de trabalho, juntamente com a educação contínua sobre o manejo do estresse, pode proporcionar aos profissionais de saúde as ferramentas necessárias para manter sua saúde mental.
Mustafa Demirci, Siyah Öfke: Ortaçağ İslâm Dünyasında Zenci Kölelerin İsyanı (869-883), Çizgi Kitabevi Yayınları, 3. Baskı, Konya 2021, 318 Sayfa, ISBN: 9786051960272
Authors: Naimi Muhammed Naim
Published: January 2025

During the Abbasîd period, Prof. Dr. Mustafa Demirci’s monograph on the ‘black rebellion’ that took place between 869-883 A.D. and was led by the Shiite leader Ali b. Muhammad, titled “Black Rage: The Rebellion of Zanj Slaves in the Medieval Islamic World (869-883)” by Prof. Dr. Mustafa Demirci is one of the most important studies both in terms of its subject matter and the author’s approach and perspective on the subject. The study, which was prepared with a rich academic iteratüre using basic sources and modern research on the subject, deals with issues such as the geography of the event, the causes and spread of the rebellion, the wars and warfare techniques to suppress the rebellion, the short and long-term effects of the damage left behind by the rebellion from an academic perspective in chronological order. The zanj rebellion started in the marshes of Basra in 869 as a result of Ali b. Muhammad (d. 883), who was originally white and claimed to be a descendant of the Prophet Ali (d. 883), organizing black slaves working under difficult conditions in the large farms in and around Basra, and the rebellion grew and spread in a short time. Muwaffak Billāh (843-891), the brother of the Abbasid Caliph Mu’temid Alallah’ın (843-892), who was assigned to suppress the rebellion, was victorious against the rebels after tough struggles, and the rebellion ended with the killing of the leader of the rebellion, Ali b. Muhammad, in 883.
Challenges and Solutions for Using Waste Materials in Various Construction Applications
Authors: Putra Jaya Ramadhansyah , Munirwan Reza Pahlevi , Bunyamin Bunyamin
Published: January 2025

The construction industry faces growing challenges in managing waste materials while striving for sustainability and resource efficiency. Incorporating waste materials into construction processes can mitigate environmental issues, reduce resource consumption, and enhance sustainability. This volume two of the Smart and Green Materials Journal explores the potential of utilizing waste materials in various construction applications, highlighting both the opportunities and obstacles associated with their integration. Key challenges include inconsistent material properties, environmental risks, and the absence of standardized guidelines for safe and effective use. Proposed solutions focus on advanced material characterization, innovative processing technologies, and the establishment of supportive policies and frameworks. By addressing these issues, the adoption of waste materials in construction can lead to reduced environmental impacts, cost savings, and the promotion of circular economy principles in the built environment.
A Comprehensive Literature Review of Relationship of Inflammatory Bowel Disease and Celiac Disease
Authors: Erick Persson Jeffry  , Charles Sanjaya Seikka
Published: January 2025

Background: The relationship between Inflammatory Bowel Disease (IBD) and Celiac Disease (CeD) has garnered significant attention in recent research, revealing complex interactions that may inform both pathogenesis and treatment strategies. Literature Review: The variability in prevalence rates of CeD among IBD patients, as reported by (Bengi et al., 2019), underscores the complexity of these diseases and the interplay of genetic, environmental, and immunological factors. This is further supported by (Hyun, 2021), who explore the connections between metabolic disorders and IBD, suggesting that chronic intestinal inflammation may predispose individuals to additional health issues, thereby reinforcing the idea of shared inflammatory pathways. Additionally, (Akiyama et al., 2022) elucidates the increased prevalence of CeD in patients with immune-mediated inflammatory diseases, indicating that the coexistence of these conditions can influence clinical outcomes. Finally, (Yemula, 2024) emphasizes the role of gut microbiota in the pathophysiology of CeD, suggesting that microbial changes may influence both conditions. The interconnectedness of IBD and CeD is evident, with shared genetic, immunological, and environmental factors driving the relationship. The literature collectively advocates for further research to clarify these interactions and improve patient management strategies, particularly regarding screening and dietary considerations. Conclusion: In conclusion, the relationship between IBD and CeD is characterized by complex interactions influenced by shared genetic predispositions, environmental factors, and dysregulated gut microbiota. The findings underscore the necessity for a nuanced understanding of these conditions to enhance diagnostic approaches and treatment strategies.
A Comprehensive Literature Review of Relationship of Insuline Resistance and Thyroid Cancer
Authors: Erick Persson Jeffry  , Charles Sanjaya Seikka
Published: January 2025

Background: The relationship between insulin resistance and thyroid cancer has garnered increasing attention in recent years, as emerging evidence suggests a complex interplay between metabolic disorders and cancer risk. Literature Review: The study by (Malaguarnera et al., 2012) outlines the role of insulin and IGFs in promoting cell proliferation and migration, implicating these factors in tumorigenesis. This perspective is echoed in the literature review by (Shih et al., 2012), which discusses the rising incidence of thyroid cancer, particularly in small tumors, and emphasizes the need to investigate the role of diabetes and metabolic syndrome further. The meta-analysis conducted by (Yeo et al., 2014) reinforces the association between diabetes and thyroid cancer, suggesting that insulin resistance may be a significant contributor to this risk. Meanwhile, (Chiefari et al., 2021) explores the mechanisms linking chronic hyperinsulinemia to cancer development, emphasizing the importance of inflammatory processes in this relationship. Recent research by (Xu et al., 2022) specifically isolates the effects of insulin resistance in euthyroid patients, further supporting the notion that insulin resistance is a risk factor for differentiated thyroid cancer. Lastly, (Wu et al., 2024) synthesizes the current understanding of diabetes and thyroid cancer, identifying several mechanisms, including oxidative stress and hyperinsulinemia, that may underlie this association. Conclusion: In conclusion, the reviewed literature collectively underscores the significance of insulin resistance as a potential risk factor for thyroid cancer. It highlights the need for further studies to elucidate the biological mechanisms involved and to explore the implications for prevention and treatment strategies. The complexity of the relationship between metabolic disorders and cancer risk suggests that a multi-faceted approach is necessary for future research.
A Comprehensive Literature Review of Management and Quality of Life of Hepatocelullar Carcinoma
Authors: Erick Persson Jeffry  , Charles Sanjaya Seikka
Published: January 2025

Background: The management of hepatocellular carcinoma (HCC) is a multifaceted challenge that significantly impacts patients' quality of life (QoL). The literature reveals a growing body of research dedicated to understanding the intricate relationship between HCC management and health-related quality of life (HRQoL), as evidenced by a series of systematic reviews and studies spanning over a decade. Literature Review: The systematic review conducted by (Fan, 2011) underscores that patients with HCC experience a notably poorer HRQoL compared to those with chronic liver disease and the general population. Further, the global survey by (Gill et al., 2018) highlights significant gaps in patient information at diagnosis, with a majority feeling inadequately informed. The exploration of advanced HCC treatment options by (Li et al., 2019) reveals that while curative therapies exist for early-stage HCC, patients often present with advanced disease, where treatment options are limited. The study by (Zhou & Fountzilas, 2019) further examines the impact of systemic therapies on QoL, revealing that side effects from anticancer agents can lead to treatment interruptions, thereby diminishing the overall efficacy of the treatment. This finding highlights the importance of ongoing research to manage drug toxicity and improve the QoL of patients undergoing systemic therapy. The systematic review by (Wohlleber et al., 2021) advocates for standardized HRQoL measures, emphasizing their importance in informing treatment strategies and enhancing patient care. The review also discusses various HRQoL instruments, underscoring the need for their integration into clinical practice to better capture the patient experience. n examining prognostic factors, (Minami et al., 2022) emphasizes the role of early detection and effective management of HCV in improving both survival rates and QoL Conclusion: In conclusion, the literature collectively emphasizes the intricate interplay between HCC management and quality of life. There is a clear need for continued research and enhanced clinical practices that prioritize patient-centered care, effective communication, and the integration of psychosocial support to improve the overall QoL for individuals living with HCC.
A Comprehensive Literature Review of Diagnosis and Management of Multi Drug Resistant Tuberculosis
Authors: Erick Persson Jeffry  , Charles Sanjaya Seikka
Published: January 2025

Background: The review of the literature on the diagnosis and management of multidrug-resistant tuberculosis (MDR-TB) reveals a pressing global health challenge characterized by complex factors influencing its prevalence and treatment. (Chhabra et al., 2012) lay the groundwork by identifying systemic issues such as inadequate healthcare resources and poor case detection as significant contributors to the MDR-TB epidemic.  Literature Review: (J. Sloan & M. Lewis, 2016) further contribute to the discourse by exploring novel treatments and their applicability in low-resource environments. They emphasize the importance of improved diagnostics and the integration of new therapeutic strategies, while also addressing the financial barriers associated with MDR-TB treatment. (Kolloli & Subbian, 2017) shift the focus to host-directed therapies, arguing for innovative management strategies to address the complexities introduced by co-infections and chronic illnesses. They call for a reevaluation of traditional treatment regimens, particularly for patients with MDR- and extensively drug-resistant tuberculosis (XDR-TB), highlighting the need for approaches that enhance effectiveness. (Yadav, 2023) reviews recent advancements in MDR-TB research, particularly in diagnostic technologies and treatment methodologies. The article reinforces the urgency of addressing the global challenge posed by MDR-TB through innovative strategies that facilitate faster and more accurate diagnosis, ultimately aiming for improved patient outcomes. Conclusion: In conclusion, the literature collectively illustrates the dynamic and intricate landscape of MDR-TB management. The articles underscore the critical need for continued research, enhanced diagnostics, and innovative treatment strategies to effectively combat this growing public health crisis. A multifaceted approach that includes international collaboration, financial investment, and the integration of new technologies is essential for addressing the challenges posed by MDR-TB and improving patient outcomes.
Realidad. Una construcción social
Authors: Vázquez Pérez Eduardo Daniel
Published: January 2025

La realidad tal y como la conocemos no es en sí la realidad, es sólo una concepción de lo que socialmente nos han dicho que es la realidad social porque se ha impuesto. Esto como consecuencia de que la realidad social no es estática, dado que se encuentra en un constante dinamismo que se refuerza en las relaciones sociales y el lenguaje que emplean los sujetos sociales con el que construyen verdades artificiales para compartirlas en el entramado de la vida social para nombrar, etiquetar y significa de manera legítima lo conocido. No obstante, es importante recordar que el lenguaje empleado por parte de los entes sociales no es otra cosa que un instrumento racionalizado por el poder que tiene la finalidad de controlar, coaccionar, administrar y subordinar a los entes sociales a través de la implementación de ideologías, por lo que su desconocimiento y superación se convierten en una enorme tarea para liberarse de las diversas formas de violencia estructural que imperan en la sociedad.
Feminismo Comunitario y el binomio del Chacha (hombre)-Warmi (mujer) en el Cono Sur
Authors: Huanca-Arohuanca Jesús Wiliam
Published: January 2025

Hablar de los movimientos feministas es siempre controversial, más todavía, cuando es el hombre quien busca entender el entramado de la mujer frente a los patriarcados establecidos en América Latina (AL). El propósito del ensayo es introducir al debate a un feminismo comunitario que observa la presencia del binomio Chacha-Warmi en los aposentos de la superficie Aimara frente al ascenso del feminismo radical. Teniendo la brújula precedente como enunciado, se aborda en principio el espectro de la Pachamama como matriz del feminismo comunitario y, en el seno secundario, se insiste en la persecución de ideales y principios a través de algunas exponentes de referencia que sustentan el feminismo comunitario. Finalmente, la idea es construir una alternativa frente al proyecto de colonialidad presente en las agendas gubernamentales y el marco de contingencias que colocan a la mujer en medio de un fuego cruzado entre la discriminación de género, las relaciones de poder, racismo y la violencia de género.
Editorial for the Second Volume of the Journal of Educational Impact
Authors: Soyer Mehmet
Published: January 2025

As we present the second volume of the Journal of Educational Impact, we are proud to showcase a diverse collection of research and reflections that highlight the transformative power of education in fostering equity, empathy, and critical engagement. This volume brings together innovative studies and thought-provoking analyses that address some of the most pressing challenges in education today, from community-based learning to pedagogical partnerships and the evolving role of leadership in times of crisis. Each contribution offers valuable insights for educators, researchers, and practitioners committed to creating meaningful and inclusive learning environments.
Efektivitas Penerapan Pendekatan Kontekstual dengan Strategi REACT (Relating, Experiencing, Applying, Cooperating, Transfering) dalam Pembelajaran Matematika Siswa Kelas VTK SD Mangkura Makassar
Authors: Hadia Veronika
Published: January 2025

Penelitian ini bertujuan untuk mengetahuai efektivitas penerapan Pendekatan Kontekstual dengan strategi REACT (Relating, Experiencing, Applying, Cooperating, Transfering) dalam pembelajaran matematika siswa kelas V SD MangkuraMakassar. Jenis penelitian ini adalah pre eksperimen dengan desain One Grup Pretest-Posttest Design. Populasi dalam penelitian ini adalah seluruh siswa kelas VTK SD MangkuraMakassar yang terdiri dari tiga kelas dan sampel yang digunakan adalah siswa kelas V1 yang berjumlah 25 orang. Analisis statistik yang digunakan adalah analisis deskriptif dan inferensial. Dari hasil analisis tersebut diperoleh bahwa: 1) Hasil  belajar siswa sebelum menerapkan Pendekatan Kontekstual dengan strategi REACT (Relating, Experiencing, Applying, Cooperating, Transfering) berada pada kategori rendah dengan rata rata 60,08 dengan standar devisiasi 14,734 sedangkan  hasil belajar siswa setelah  menerapkan Pendekatan Kontekstual dengan strategi REACT (Relating, Experiencing, Applying, Cooperating, Transfering) berada pada kategori tinggi dengan rata-rata 84,24 dengan standar devisiasi 11,092 serta berdasarkan pengujian hipotesis pada taraf signifikan α=0,05 dengan dk=24 diperoleh  yang berarti bahwa rata-rata hasil belajar siswa juga melebihi KKM; 2) Terjadi peningkatan dari pretest ke posttest dengan nilai gain 0,60 dan berada pada kategori sedang; 3) Persentase aktivitas siswa  sebesar 83,33% dan berada pada kategori sangat aktif; 4) Persentase respon siswa sebesar 81,6% dan berada pada kategori positif; 5) Persentase keterlaksanaan pembelajaran sebesar 84,13% dan berada pada kategori baik. Dari hasil tersebut disimpulkan bahwa Pendekatan Kontekstual dengan strategi REACT (Relating, Experiencing, Applying, Cooperating, Transfering) efektif dalam pembelajaran matematika siswa.
HAPPINESS AND ACADEMIC ACHIEVEMENT OF STUDENTS IN THE MATHEMATICS AND NATURAL SCIENCE FACULTY, UNIVERSITY OF MAKASSAR
Authors: Ngitung Rosdiana
Published: January 2025

Penelitian ini bertujuan untuk mengetahui hubungan antara kebahagiaan dan prestasi akademik mahasiswa Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Negeri Makassar. Selain itu peneliti memperoleh gambaran perbedaan kebahagiaan antara mahasiswa laki-laki dan perempuan serta faktor-faktor penyebab kebahagiaan. Jumlah responden dalam penelitian ini adalah sejumlah 135 mahasiswa Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Negeri Makassar. Alat ukur yang digunakan dalam penelitian ini Adalah Dispositional Positive Emotions Scale yang dibuat oleh Shiota, Kaltner, dan John pada tahun 2006 untuk mengukur kebahagiaan dan Indeks Prestasi Kumulatif (IPK) untuk mengukur prestasi mahasiswa. Hasil penelitian menunjukkan bahwa kooefisien korelasi sebesar 0,607 dengan nilai signifikansi sebesar 0,000 (p<0,05). Hasil ini menunjukkan bahwa terdapat hubungan antara kebahagiaan dan prestasi akademik mahasiswa di Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Negeri Makassar. Penelitian ini juga menunjukkan bahwa mahasiswa perempuan lebih memiliki kebahagiaan yang tinggi dibandingkan laki-laki. Mahasiswa di Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Negeri Makassar memiliki adaptasi dan penyesuaian diri yang baik serta interaksi sosial yang baik dengan lingkungan kampus sehingga dapat meingkatkan kebahagiaan dan prestasi akademik mahasiswa.
The Political Theory Journal’s contribution to the establishment and advancement of the Ho Chi Minh National Academy of Politics
Authors: NGUYEN THANG LOI
Published: January 2025

The Political Theory Journal is a scholarly research and commentary agency of the Ho Chi Minh National Academy of Politics, periodically releasing three publications: a Vietnamese print edition, an English print edition, and an electronic journal available in both Vietnamese and English. The Journal actively contributes to the fulfillment of the Academy’s political objectives by implementing the principles and purposes of disseminating and educating Marxism-Leninism, Ho Chi Minh’s ideology, the Party’s guidelines and directives, as well as the State’s policies and laws; reporting on and reflecting the accomplishments of theoretical research and summarizing practical experiences; and combating and refuting erroneous and antagonistic viewpoints against the Party’s guidelines.
Optimizing 5G Resource Allocation in PSO with Machine Learning Approach to Open RAN Architectures
Authors: Hussien Osama , Jahankhani Hamid
Published: January 2025

This paper proposes a novel machine learning-based approach to solve the resource allocation problem in 5G Open Radio Access Networks (O-RAN). While traditional methods rely on meta-heuristic optimization techniques such as Whale Optimization Algorithm (WOA), we present an ensemble learning framework that combines multiple advanced algorithms to achieve efficient and practical resource allocation. Our approach decomposes the complex mixed-integer non-linear programming (MINLP) problem into two complementary tasks: Remote Radio Head (RRH) assignment through classification and Physical Resource Block (PRB) allocation through regression. Through extensive experimentation, we demonstrate that our ensemble method achieves 75-78\% accuracy in RRH assignment with mean squared error of 0.3922 in PRB allocation, while providing near-instantaneous decision-making capabilities after training. The proposed solution offers significant advantages in computational efficiency and scalability compared to traditional optimization approaches, particularly in scenarios requiring real-time resource allocation decisions. Furthermore, we present a comprehensive comparative analysis between our machine learning approach and existing optimization-based methods, highlighting the trade-offs and complementary strengths of each approach. Our findings suggest that machine learning-based resource allocation can serve as a viable alternative or complement to traditional optimization methods in 5G networks.
GASÁ SA GAZA: PANITIKAN AT PANININDIGAN SA PANAHON NG DIGMA
Authors:   Polytechnic University of the Philippines, MJ Rafal
Published: January 2025

Matindi ang hamon ng taong 2023.

Bago matapos ang taon, lumantad sa ating lahat ang lagim na matagal nang nangyayari sa Gaza—ang paglipol ng Israel sa mga Palestino, ang sistematikong pagpapaalis sa lupaing marapat namang para talaga sa mga katutubong Palestino. Ngunit hindi sa kaso ng Israel na kinasasapakat ng imperyalistang Estados Unidos upang tuloy-tuloy ang opensibang militar laban sa mga inaakusahang teroristang Hamas, pinalalabnaw ang rebolusyunaryong diwa ng pagbawi para pulbusin ang hindi naman mapupulbos na adhika at tapang ng mga Palestino na ipaglaban ang kanilang lupa at lahi. Wika nga ni Yahya R. Sarraj, ang mayor ng Gaza, sa kanyang maikling artikulo sa The New York Times, “Palestinians deserve to be free and have self-determination. Gaza’s emblem is the phoenix, which rises from the ashes. It insists on life” (2023).

Hindi na ito usapin na lamang ng relihiyon. Lupa at lupa pa rin ang dahilan kung bakit may digmaan. At laging ang mga bata, kababaihan at matatanda ang unang nasasawi sa ganitong lagim. Tuloy-tuloy rin ang digmaan sa pagitan ng Ukraine at Russia. Tila ba nasa bingit tayo ng napipintong pagkawasak at ang tanging nagagawa na lamang natin ay sumaksi sa mga nangyayari at maaari pang mangyari.

Ngunit kung saksi lamang tayo sa pagbangon ng phoenix mula sa abo, hindi ba’t tila kasabwat na rin tayo ng mga kaaway habang may lagim na nailalantad sa ating harapan? Gayunman ang maibabato ng karaniwang tao: ano ang magagawa ng tulad kong maliit sa ganito kalalaking pangyayari?

Dito marahil pumupuwang ang panitikan. Dito nagkakaroon ng kahulugan ang manunulat.
Philippine Women Leaders’ Presence, Practices, and Challenges in Higher Education in the New Normal
Authors:   Polytechnic University of the Philippines, Manimtim Herminia , Perez Emeteria Leonila ,   Polytechnic University of the Philippines
Published: January 2025

The Covid-19 pandemic confronted the educational system by surprise and compelled school leaders to enforce decisive institutional policies and changes to maintain community cohesion and students’ learning and well-being without the benefits of physical classrooms and campuses. The new normal calls for greater women leadership participation in educational institutions. This paper then expounds and draws attention on themes such as women’s presence in school administration, barriers that limit women leadership advancement and participation, women leaders’ qualities and practices, and challenges faced as leaders in the new normal educational milieus. A focused review of ideas and perspectives about women leadership and an integrative presentation of relevant data from literature were utilized.
Apport de la m é thode de détoxification par humidification de la farine de manioc dans la lutte contre le Konzo dans le district de Kwango
Authors: BALOW’A KALONJI KAMUNA Ignace , KANKU KALALA André
Published: January 2025

Le Konzo est une paralysie spastique, dont l’apparition est brusque, permanente et incurable des membres inférieurs. Il est une maladie neurologique attribuée à l’exposition au cyanure du fait de la consommation prolongée de grandes quantités du manioc insuffisamment traité. L’objectif général de cette étude est d’évaluer l’apport de la méthode de détoxification par humidification de la farine de manioc dans la lutte contre le Konzo dans un district de la province de Kwango. La quintessence de la méthode consiste à ajouter petit à petit, dans une quantité de la farine de manioc disponible à la préparation de fufu, de l’eau propre, en remuant constamment, jusqu’à ce que la farine soit humide. Et le mélange obtenu est séché au soleil avant son utilisation. Une étude rétrospective est réalisée sur des données colligées sur un échantillon de 746 enfants âgés de 6-14 ans, durant la période de trois ans par le PRONANUT dans les différents villages de l’actuelle Province du Kwango. Une prévalence de 16% des cas de Konzo dans les ménages enquêtés et une diminution significative de la teneur en thiocyanate dans les urines des enquêtés ont été trouvées à la fin de la période d’étude. L’intégration de la méthode de détoxification par humidification de la farine de manioc dans les habitudes alimentaires de la population de la province de Kwango, aboutit à une diminution significative de la teneur en thiocyanate dans les urines des enquêtés, trois ans après.
Aspect épidémiologique de la cataracte dans la pathologie ophtalmologique de la ville de Bumba
Authors: NGANA MANGONGO HIBA
Published: January 2025

Nous avons effectué une étude rétrospective de la cataracte à l’Hôpital Général de Référence de Bumba. Les éléments étudiés étaient: la fréquence, les sexes, l’âge, les types de cataractes, la localisation de lésion, la provenance des sujets et les types de cataractes. Il ressort des résultats trouvés que sur 600 malades consultés pour les problèmes ophtalmologiques, 450 cas soit 75% concernaient la cataracte. Parmi eux, il y avait 45,3% des malades de sexe masculin et 54,7 % de sexe féminin. Les malades venant des milieux ruraux représentaient 50%, ceux de la ville de Bumba 24 %. Les lésions des cataractes étaient de 64,4 % bilatérales et 35,5 % unilatérales. Le type de cataractes secondaires était le plus représenté (47,1%), séniles (35,8%), traumatique (16,2%) et infantile (0,9%).