bluuebunny/crossref_metadata_2025 huggingface dataset:
Gender differences in the observation of gesture distance: a physiological study
Authors: Gallo Fabrizia , González-Villar Alberto , Ott Laurent , Sampaio Adriana , Nandrino Jean-Louis , Bartolo Angela
Published: July 2023

Intransitive gestures are expressive and symbolic, whereas pantomimes are object-related actions. These gestures convey different meanings depending on whether they are directed toward (TB) or away from the body (AB). TB gestures express mental states (intransitive) or hygiene/nutritional activities (pantomime), while AB gestures modify the behavior of the observer (intransitive) or demonstrate tool use with an object (pantomime). A substantial body of literature suggests that females exhibit stronger social cue processing compared to males. Considering the social significance of gestures, this study aims to explore the physiological gender differences in the observation of AB and TB gestures.
Pupil dilation and High Frequency Heart Rate Variability (HF-HRV) were measured in 54 participants (27 female) while observing TB and AB gestures. The Interpersonal Reactivity Index (IRI) and the Vicarious Distress Questionnaire (VDQ) were used to assess social-emotional processes. Results showed greater pupil dilation in females for TB gestures, but no significant gender differences for HF-HRV. Males showed a significant correlation between increased pupil dilation to both TB and AB gestures and empathy levels (IRI). The support scale of the VDQ correlated significantly with TB gestures in males. These findings provide insight into the neurobiological basis of gender differences in perceiving social gestures.
High dimensional mass cytometry analysis unravels distinct profiles of peripheral blood mononuclear cells in patients with neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein associated disease or in health
Authors: yao mengyuan , Wang Wenjing , Sun Jiali , Guo Tianshu , Bian Jiangping , Xiao Fuyao , Li Yuanyuan , Cong Hengri , Wei Yuzhen , Zhang Xinghu , Liu Jianghong , Yin Linlin
Published: July 2023

Background
Neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein-antibody associated disease (MOGAD) are rare demyelinating diseases of the central nervous system but can cause severe disability. Although these two diseases share inherent similarities, they show different pathogenesis, clinical features, and treatment response. Investigation performed by a more powerful approach is needed.
Methods
Cytometry by time-of-flight mass spectrometry (CyTOF) was used to cluster and phenotype the immune cell subsets in peripheral blood mononuclear cells (PBMCs) isolated from patients with NMOSD or MOGAD and healthy controls (HC). RNA sequencing was used to screen pivotal genes. The obtained algorithm-based data were further verified through traditional flow cytometry and qPCR analysis.
Results
We identified 29 cell clusters and found several immune cluster changes between NMOSD and MOGAD. Interestingly, no significant differences were found in the B cells fraction between patients and HC group. Immunity dysfunction was mainly attributed to changes of diverse subsets in T cells and mononuclear phagocytes (MNPs). Similar properties of two distinct CD56 + natural killer (NK) cell phenotypes and transcription factor T-bet + or chemokine receptor CCR2 + subsets were shown between patients and health.
Conclusions
Our results show an overview of the circulating PBMCs landscape of NMOSD and MOGAD patients compared to that of HC. Our data reveal that different immune phenotypes may involve in the distinct pathogenesis of NMOSD and MOGAD and highlight T cells or MNPs as a potential target for precision treatment.
Artificial intelligence-based assistance in clinical 123I-FP-CIT SPECT scan classification
Authors: wolfswinkel evander , wielaard jette , lavalaye jules , hoff jorrit , booij jan , de wit tim , habraken jan
Published: July 2023

Purpose
Dopamine transporter (DAT) imaging with 123I-FP-CIT SPECT is used to support the diagnosis of Parkinson’s disease (PD) in clinically uncertain cases. Previous studies showed that automatic classification of 123IFPCIT SPECT images (marketed as DaTSCAN) is feasible by using machine learning algorithms. However, these studies lacked sizable use of data from routine clinical practice. This study aims to contribute to the discussion whether artificial intelligence (AI) can be applied in clinical practice. Moreover, we investigated the need for hospital specific training data.
Methods
A convolutional neural network (CNN) named DaTNet-3 was designed and trained to classify DaTSCAN images as either normal or supportive of a dopaminergic deficit. Both a multi-site data set (n = 2412) from the Parkinson’s Progression Marker Initiative (PPMI) and an in-house data set containing clinical images (n = 932) obtained in routine practice at the St Antonius hospital (STA) were used for training and testing. STA images were labeled based on interpretation by nuclear medicine physicians. To investigate whether indeterminate scans effects classification accuracy, a threshold was applied on the output probability.
Results
DaTNet-3 trained with STA data reached an accuracy of 89.0% in correctly identifying images of the clinical STA test set as either normal or with decreased striatal DAT binding (98.5% on the PPMI test set). When thresholded, accuracy increased to 95.7%. This increase was not observed when trained with PPMI data, indicating the incorrect images were confidently classified as the incorrect class.
Conclusion
Based on results of DaTNet-3 we conclude that automatic interpretation of DaTSCAN images with AI is feasible and robust. Further, we conclude DaTNet-3 performs slightly better when it is trained with hospital specific data. This difference increased when output probability was thresholded. Therefore we conclude that the usability of a data set increases if it contains indeterminate images.
Visual Attention Is Not Attuned to Non-Human Animal Targets’ Pathogenicity: An Evolutionary Mismatch Perspective
Authors: Rengiiyiler Sezer , Teközel Mert
Published: July 2023

A considerable amount of research has revealed that there exists an evolutionary mismatch between ancestral environments and conditions following the rise of agriculture regarding the contact between humans and animal reservoirs of infectious diseases. Based on this evolutionary mismatch framework, we examined whether visual attention exhibits adaptive attunement toward animal targets’ pathogenicity. Consistent with our predictions, faces bearing heuristic infection cues held attention to a greater extent than did animal vectors of zoonotic infectious diseases. Moreover, the results indicated that attention showed a specialized vigilance toward processing facial cues connoting the presence of infectious diseases, whereas it was allocated comparably between animal disease vectors and disease-irrelevant animals. On the other hand, the pathogen salience manipulation employed to amplify the participants’ contextual-level anti-pathogen motives did not moderate the selective allocation of attentional resources. The fact that visual attention seems poorly equipped to detect and encode animals’ zoonotic transmission risk supports the idea that our evolved disease avoidance mechanisms might have limited effectiveness in combating global outbreaks originating from zoonotic emerging infectious diseases.
(Un)Usual Stories about Drunkenness: An Example of Vinjak as a Cultural-Symbolic Resource
Authors: Milanović Minić Nevena
Published: July 2023

This paper aims to map and analyse the central themes in narratives of alcohol intoxication caused by a popular type of strong alcoholic beverage – vinjak. Stories of being “drunk on vinjak” are distinctive compared to other forms of intoxication, and the specific events and atmosphere of such drunkenness are attributed to the characteristics of said beverage. Vinjak thus takes on a specific cultural-symbolic potential within and, accordingly, to the broader social context in which it was created and is being consumed. Narratives of drinking and intoxication are generated post-festum, through the reconstruction of events and actors, and are treated as a specific form of narrative genre. By emphasizing and exploiting the mismatch and lack of order, as well as the transgression of social rules and conventions, drunken stories are intended to arouse curiosity and ‘scandalise’ the listeners, while also sending cultural messages about the potential risks and consequences of vinjak-intoxication.
On the Possibilities and Constraints of Studying the Ethnic Makeup of the Population Using Census Data from the Principality and Kingdom of Serbia: the Case of Eastern Serbia
Authors: Knežević Aleksandar
Published: July 2023

Since the first half of the nineteenth century, various census data have been collected regarding the ethnic characteristics of the Serbian population, although the data are incomplete and collected irregularly. The ten censuses conducted in the Principality of Serbia between 1833 and 1874 have immense archival value, but their usefulness for ethno-demographic studies is limited. Similarly, while the statistics collected in the censuses of the Kingdom of Serbia from 1874 to 1910 are somewhat more reliable than the previous ones, they suffer from the absence of a direct question on ethnicity.

To determine the ethnic structure of the population during this time period, a researcher had to rely on an indirect approach through the identification of ethnic groups based on their linguistic affiliation. However, it is important to note that this method only provides an approximate estimation of ethnic composition. Despite this limitation, available census data can still provide valuable insights into the ethnic composition of the population of the Principality and Kingdom of Serbia, with the number and share of the Vlach population as the most numerous ethnic minority taking centre stage. This means that any data analyses must begin with the understanding that the indicators can only be presented for the Romanian-speaking population.

If we accept the indirect approach to determining population ethnicity, we can deduce from the data that the number of Vlachs in Eastern Serbia increased up to 1895, and their percentage share increased up to 1884. It is noteworthy that the dynamics of the number of Vlachs until 1895 were relatively stable, implying that the increase was practically linear and consistent with the growth tendency of Serbia’s overall population at the time.

Within the framework of demographic analysis, data on declared Vlachs in almost all censuses since the post-war census cannot be used to derive explainable demographic indicators. Therefore, it is reasonable to suspect that such data would also be of limited use in other academic fields, particularly in law, politics, and public life in general. This highlights the importance of paying closer attention to earlier ethno-statistic records, especially the first statistical aberration reported in the last decade of the nineteenth century.
Wikipedia as a Battleground for an Exclusive Ethnic Appropriation of Cultural Heritage: Who Does Avdo Međedović Belong to?
Authors: Raković Slaviša
Published: July 2023

Wikipedia, consisting of articles from various areas of knowledge, drawn from natural and social sciences as well as from different domains of culture, is one of the most widely read webpages. Although it does not pretend to be a location where ‘truth’ can be found, one of the principles of Wikipedia is the verifiability of information, i.e. editors have an obligation to reference their sources. Nevertheless, many Wikipedia texts of interest to different and often conflicting cultural groups show bias towards one interpretation of ‘truth’. This is not surprising, because Wikipedia is open for anyone to create content. It is also not surprising that Wikipedia has become a battleground of different narratives, given that it is one of the most popular pages on the Internet. Wikipedia texts in different languages ​​on issues of the ethnic ‘ownership’ of certain segments of cultural heritage in the Balkans are interesting illustrations of this kind of struggle over dominant narratives. As a specific example in this text, I use Wikipedia resonances of the findings of Milman Parry, the Harvard classicist, from his journey to Yugoslavia in the 1930s. Parry, with the help of his student Albert Lord and local fixer Nikola Vujnović, interviewed many guslars from Herzegovina, Montenegro and Serbia, and recorded and wrote down their songs. Academic interpretations of the findings had a significant echo, both within academia and the wider public sphere, even back then, and it continues to this day. One of the ‘consequences’ of this echo nowadays concerns the exclusive ethnic-cultural appropriation of the guslars in the context of ethnic and geopolitical tensions in the Balkans. The availability of Parry and Lord’s recorded material and transcripts on the Internet in the last couple of decades has contributed to the popularisation among a wider audience of the topic of the ethnic origin of the guslars the two academics spoke with. These tensions surrounding the issue of origin of certain guslars within academic and popular discourse have also penetrated Wikipedia. In this paper it is claimed that Wikipedia biographies of the most famous of Parry and Lord’s guslar interlocutors reflect existing academic and popular discourses regarding the process of establishing the ethnic Self while distancing oneself from ‘Others’. Specifically, an insight into the multilingual Wikipedia biography entries of Avdo Međedović, dubbed the Homer of the Balkans, shows how different communities of memory, through ethno-politically motivated citation strategies on Wikipedia, directly or indirectly deny one another cultural authenticity.
Development of a Low-Cost Monitoring and Warning System for a Data Processing Room
Authors: TİMUR Oğuzhan , TEKE Ahmet
Published: July 2023

Continuity is crucial in systems that provide uninterruptible service. When errors or warnings occur, they should be reported to the responsible people as quickly as possible and fixed right away. Since manual control will cause errors, monitoring and control should be performed automatically. In order to fill this need, expensive hardware and software are used in the market. The purchased package includes a lot of extra features that are not required. Additionally, the majority of these systems use brand-specific sensors and other hardware components. In this study, the identical operation is carried out with significantly greater cost efficiency and brand independence by using microcontroller-based hardware. The designed system can be operated in desktop, web and mobile environments thanks to the computer program that is written. In the data processing center of a university hospital, the proposed cost-effective system has been used, and it has been discovered that it is capable of carrying out the same tasks as the more expensive systems.
Glycerol used for denitrification in full-scale wastewater treatment plants: nitrous oxide emissions, sludge acclimatization, and other insights
Authors: Alessio Fenu , Lennert Dockx , Sandra Van Damme , Frederik Wynants , Verhaeghe Kirke , Koen Van Laer , Joris Roels , Rosalia Delgado
Published: July 2023

Glycerol is commonly employed for denitrification purposes in full-scale wastewater treatment. In non-acclimatized biomass, the glycerol is very inefficient resulting in a high C/N ratio and low-standard denitrification rates. The acclimatization is driven by the microbial enrichment of Saccharimonadales and Propionibacteriales as found in different sampled municipal sludges flanking the dominant presence of Burkholderiales. The selective strategy is based on a very efficient process in terms of C/N ratios and standard denitrification rates, but it leads to nitrite accumulation. As a result, severe and unexpected nitrous oxide emissions were found in full-scale with emission factors up to 2.5% kgN2O (kgKJNremoved)−1. Simultaneous dosage of isobutirate in a full-scale experiment could counter the nitrous oxide emissions. As nitrous oxide emissions were found proportional to the dosed glycerol-based COD, the authors suggest that, in case of acclimatization of biomass to glycerol, an emission factor based on the dosed COD should substitute the general nitrous oxide emission factors based on incoming or removed nitrogen to the plant.
β Pore-forming Protein-based Evolutionary Divergence of Gnathostomata
from Agnatha
Authors: Kumar Bhupendra , Kashif Mohd , Alsaiari Ahad Amer , Khan Mohammad Imran , Kalam Abul , Ahmad Abrar , Lone Rayees Ahmad , Almehmadi Mazen , Dudhagi Shivanand Suresh , Zamzami Mazin A
Published: July 2023

Introduction:

The first vertebrates were jawless fish, or Agnatha, whose evolution diverged
into jawed fish, or Gnathostomes, around 550 million years ago.

Methods:

In this study, we investigated β PFT proteins' evolutionary divergence of lamprey immune
protein from Agnatha, reportedly possessing anti-cancer activity, into Dln1 protein from
Gnathostomes. Both proteins showed structural and functional divergence, and shared evolutionary
origin. Primary, secondary and tertiary sequences were compared to discover functional domains
and conserved motifs in order to study the evolution of these two proteins. The structural and functional
information relevant to evolutionary divergence was revealed using hydrophobic cluster analysis.

Results:

The findings demonstrate that two membrane proteins with only a small degree of sequence
identity can have remarkably similar hydropathy profiles, pointing towards conserved and
similar global structures. When facing the lipid bilayer or lining the pore lumen, the two proteins'
aerolysin domains' corresponding residues displayed a similar and largely conserved pattern.
Aerolysin-like proteins from different species can be identified using a fingerprint created by PIPSA
analysis of the pore-forming protein.

Conclusion:

We were able to fully understand the mechanism of action during pore formation
through structural studies of these proteins.
Recent Developed Nitrogen/Sulfur Heterocyclic Compounds with Marked and
Selective Antiviral Activities (Microreview)
Authors: Mutalabisin Fathiy , Ghafarikhaligh Mahta , Mihankhah Peyman , Khaligh Nader Ghaffari
Published: July 2023

Millions of deaths have been reported due to viral infections in medical history, and
various viral infections are mentioned as the main cause of death. Although different types of
research have been conducted to develop effective medication, there is a high demand to truly
cure various viral infections. The resistance to the existence of antiviral drugs on the market is
the main threat to human health, and an intrinsic demand to develop and synthesize new scaffolds
is highly required to find less toxicity and high antiviral activity. Nitrogen-sulfur heterocyclic
compounds have extensively exhibited efficient biological and pharmacological activity
against viral species, and physicochemical and pharmacokinetic properties. In this microreview,
recently developed nitrogen-sulfur heterocyclics and their performance with
marked and selective antiviral activities are summarized. We hope this micro-review will help
early scientists interested in the design of new compounds with selective and pronounced antiviral activities
to identify and satisfy the necessary criteria for the further development of nitrogen-sulfur heterocyclic compounds.
Synthesis and Characterisation of Flavonoid Mannich Bases and the
Evaluation of their Cytotoxic Activity
Authors: Chang Chew-Cheen , Sim Kooi-Mow , Lim Tuck-Meng , Pichika Mallikarjuna Rao , Mak Kit- Kay
Published: July 2023

With multi-drug-resistant tumours continuously evolving, developing new drugs with
enhanced efficacy is essential. This study aims to synthesise flavonoid Mannich bases and evaluate
their cytotoxic activity. The flavonoids isolated from the leaves of Muntingia calabura were used as
reactants for the synthesis. Twenty flavonoid Mannich bases were synthesised via the Mannich
reaction. Cytotoxic activity of the parent compounds and synthesised compounds were evaluated
against two breast cancer cell lines, i.e., MCF-7, MDA-MB-231, and one normal breast cell line,
MCF-10A, via MTT assay. Cytotoxic activity against the MDA-MB-231 cancer cell line showed that
flavonoid Mannich bases exhibited greater activity than their parent compounds. 5,7-dihydroxy-8-(4-
methoxybenzylamine)-2-phenyl-4H-chromen-4-one (4f) showed the highest cytotoxic activity against
MDA-MB-231 cell with IC50 of 5.75±0.82 μM. For the MCF-7 cell line, the parent compounds and
Mannich bases showed moderate activity with the IC50 range of 9.17-68.5 μM. For cytotoxic activity
against the MCF-10A cell line, the parent compound, 5,7-dihydroxyflavone (4), showed the highest
toxicity against MCF-10A with IC50 of 10.55±1.05 μM. The results suggest synthetic modifications
have produced compounds with improved anticancer activity and selectivity against breast cancer
cells.
Intranasal Drug Delivery of Antiviral Agents - A Revisit and Way
Forward
Authors: Affrald R Jino , Narayan Shoba
Published: July 2023

Even to this date, oral drug delivery in the form of tablets, capsules, and syrups is considered
as the most accepted one. However, oral delivery as a methodology requires that the active molecules
and their formulations are water-soluble. Nasal drug delivery is characterized by ease of permeability
through the epithelial mucosa, low enzyme activity, and a wide range of immunocompetent
cells. For the transfer of drugs and active molecules through the nasal route, it is often essential to resort
to nanodelivery methods, such as liposomes, microspheres, nanoemulsions, and so on. The use of
nanodelivery vehicles has become more important in the modern context of viral infections, including
those of the respiratory tract. Nanoformulations are developed in the form of nasal gels, sprays, drops,
rinses, etc. Nanoformulations of antigens, vaccine and immune adjuvants, and antivirals are now gaining
importance. There are promising reports on nanoparticles of metals, metal oxides, polymers, and
so on that have the potential to detect and inhibit viruses by themselves. This review looks into the nasal
nanoformulations in detail and provides an insight into how their efficacy can be improved. To
overcome known drawbacks, such as degradation and active mucociliary clearance by antigenpresenting
cells at the site of administration, polymers, such as PEG, are incorporated in the nanoformulation.
Polymeric systems also provide better tunability of physicochemical properties. The mechanism
of nasal spray-based drug delivery systems is also discussed in this paper. The review, thus, provides
a detailed insight into the way forward for the development of nasal formulations.
Current Diagnosis and Treatment for Hepatocellular Carcinoma with
Macrovascular Tumor Thrombosis
Authors: Chen Zhen-Hua , Feng Jin-Kai , Liu Zong-Han , Wang Kang , Cheng Shu-Qun
Published: July 2023

Macrovascular tumor thrombosis (MVTT) is common among patients with advanced
hepatocellular carcinoma (HCC), and it contains two main types, portal vein tumor thrombus
(PVTT) and hepatic vein tumor thrombus (HVTT). MVTT is a significant prognostic factor, and
the prognosis of HCC with MVTT remains unsatisfactory. The classification of MVTT varies in
different studies, and the management of HCC and MVTT differs among Eastern and Western
countries. Over the past years, a multidisciplinary approach, including surgical resection, radiotherapy,
and transcatheter arterial chemoembolization, especially the advent of new targeted drugs
and immune checkpoint inhibitors, has brought considerable survival benefits for HCC patients
with MVTT. Recently, multiple novel treatment strategies, such as neoadjuvant therapy or tumor
downstaging based on radiotherapy, immunotherapy, and molecular-targeted therapy, have broadened
the treatment landscape of MVTT. In this review, we conclude the consensus and progress
regarding diagnosis and treatment for patients with HCC and MVTT.
Coloured Cereals: Nutritional Benefits and Therapeutic Properties
Authors: Rani Nitu , Mishra Tanya , Thakur Babita , Kaur Rajinder , Kaur Sukhminderjit
Published: July 2023

:

Worldwide, cereals are staple foods and are needed for proper growth and development of humans. In the food industry, coloured cereals have gained popularity as potential nutraceuticals. These are high in phytochemicals, which are crucial in protecting the body from allergies, cancer, diabetes, and cardiovascular disease. Due to their strong antioxidant effects, phenolic compounds have sparked a lot of interest in many scientific fields. Anthocyanins have the potential of functional food ingredient. Anthocyanins are the ubiquitous family of natural pigments which are found in large quantities in various cereals such as corn, wheat, barley, rice, sorghum and its varieties and various colored cereals like black, red, and pink cereals. Cereals contain phenolic compounds which are found in either bound or Free State, which is called the total phenolic compound content. The present review provides health benefits properties of various photochemical of cereals, including phenolics, flavonoids, anthocyanin, proanthocyanidins, tocopherols and phytates.
Disruptive Innovation as a Network Dilemma: A Conceptual Model
Authors: Ataman Kaan , Myhr Niklas , Nistor Cristina
Published: July 2023

Adoption of innovative products, formats and technologies has long been studied in the management and marketing literature. Organizations that adopt new products and processes in order to stay competitive need to determine which technologies will be the winners rather than passing fads. Extant literature has characterized the innovator’s dilemma for adopting new products from several points of view, from decision makers’ response to niche customers perspective (Christensen, 1997) to a focus on organizational capabilities (Henderson, 2006), while also characterizing the incumbent’s strategic response to disruptive innovation (Christensen et al., 2015). Our paper develops a new conceptual model of innovation adoption in markets with network effects. In particular, we focus on the problem that many current companies face: which (if any) new network will be the winner and how to respond? Our model captures surprising aspects of the disruptive innovation dilemma in networks.
Implementasi gerakan penguatan pendidikan karakter sebagai wahana pendidikan nilai
Authors: Aulia Syifa Siti , Arif Dikdik Baehaqi , Amalia Rosidah
Published: July 2023

This study aims to analyze the implementation of the movement to strengthen character education in terms of 3 aspects policy, implementation, and assessment of the implementation of activities. This research uses a descriptive method with a qualitative approach. The object of the study was the Movement for Strengthening Character Education in Kulon Progo Regency. Data collection uses observation, interview, and documentation techniques. Data analysis using interactive model analysis techniques from Miles and Huberman. The results showed that Kulon Progo district has implemented a systematic comprehensive character education strengthening movement in terms of policy, namely with the issuance of Kulon Progo Regent Regulation Number 65 of 2017 concerning guidelines for the implementation of strengthening character education in education units. The implementation of strengthening character education in Kulon Progo Regency consists of 3 main bases, namely, religion, the practice of Pancasila values, and the culture of humanity. Evaluation is carried out in the concept of monitoring and evaluation carried out through observation (direct observation) to collect data both administrative and supporting records to assess character education strengthening activities carried out by the Youth Education and Sports Office of Kulon Progo District.
Predictive modeling of marine fish production in Brunei Darussalam's aquaculture sector: A comparative analysis of machine learning and statistical techniques
Authors: Nazmi Haziq , Siau Nor Zainah , Bramantoro Arif , Suhaili Wida Susanty
Published: July 2023

The aquaculture industry has witnessed significant global growth, offering opportunities for sustainable fish production. This research delves into the application of data analytics to develop an appropriate predictive model, utilizing diverse machine learning and statistical techniques, to forecast marine fish production within Brunei Darussalam's aquaculture sector. Employing a machine learning-based algorithm, the study aims to achieve enhanced prediction accuracy, thereby providing novel insights into fish production dynamics. The primary objective of this research is to equip the industry with alternative decision-making tools, leveraging predictive modeling, to identify trends and bolster strategic planning in farm activities, ultimately optimizing marine fish aquaculture production in Brunei. The study employs various time series and machine learning techniques to generate a precise predictive model, effectively capturing the inherent seasonal and trend patterns within the time-series data. To construct the model, the research incorporates notable algorithms, including autoregressive integrated moving average (ARIMA), long short-term memory (LSTM), linear regression, random forest, multilayer perceptron (MLP), and Prophet, in conjunction with correlation analysis. Evaluation of the model's performance and selection of the optimal forecasting model are based on mean absolute percentage error (MAPE) and root mean squared error (RMSE) metrics, ensuring a robust analysis of time series data. Notably, this pioneering research stands as the first-ever attempt to forecast marine fish production in Brunei Darussalam, setting a benchmark unmatched by any existing baseline studies conducted in other countries. The experiment's results reveal that straightforward machine learning and statistical techniques, such as ARIMA, linear regression, and random forest, outperform deep learning methods like MLP and LSTM when forecasting univariate time series datasets.
Appropriateness and Comprehensiveness of Using ChatGPT for Perioperative Patient Education in Thoracic Surgery in Different Language Contexts: Survey Study
Authors: Shao Chen-ye , Li Hui , Liu Xiao-long , Li Chang , Yang Li-qin , Zhang Yue-juan , Luo Jing , Zhao Jun
Published: July 2023

Background

ChatGPT, a dialogue-based artificial intelligence language model, has shown promise in assisting clinical workflows and patient-clinician communication. However, there is a lack of feasibility assessments regarding its use for perioperative patient education in thoracic surgery.

Objective

This study aimed to assess the appropriateness and comprehensiveness of using ChatGPT for perioperative patient education in thoracic surgery in both English and Chinese contexts.

Methods

This pilot study was conducted in February 2023. A total of 37 questions focused on perioperative patient education in thoracic surgery were created based on guidelines and clinical experience. Two sets of inquiries were made to ChatGPT for each question, one in English and the other in Chinese. The responses generated by ChatGPT were evaluated separately by experienced thoracic surgical clinicians for appropriateness and comprehensiveness based on a hypothetical draft response to a patient’s question on the electronic information platform. For a response to be qualified, it required at least 80% of reviewers to deem it appropriate and 50% to deem it comprehensive. Statistical analyses were performed using the unpaired chi-square test or Fisher exact test, with a significance level set at P<.05.

Results

The set of 37 commonly asked questions covered topics such as disease information, diagnostic procedures, perioperative complications, treatment measures, disease prevention, and perioperative care considerations. In both the English and Chinese contexts, 34 (92%) out of 37 responses were qualified in terms of both appropriateness and comprehensiveness. The remaining 3 (8%) responses were unqualified in these 2 contexts. The unqualified responses primarily involved the diagnosis of disease symptoms and surgical-related complications symptoms. The reasons for determining the responses as unqualified were similar in both contexts. There was no statistically significant difference (34/37, 92% vs 34/37, 92%; P=.99) in the qualification rate between the 2 language sets.

Conclusions

This pilot study demonstrates the potential feasibility of using ChatGPT for perioperative patient education in thoracic surgery in both English and Chinese contexts. ChatGPT is expected to enhance patient satisfaction, reduce anxiety, and improve compliance during the perioperative period. In the future, there will be remarkable potential application for using artificial intelligence, in conjunction with human review, for patient education and health consultation after patients have provided their informed consent.
Epidemiological Investigation of Neonatal Jaundice in Tikrit City: Assessing Neonatal Risk Factors from 2022 to 2023
Authors: Al-Jiboury Firdous Salih M. , Salman Abid Ahmed , Sarhat Ashoor R
Published: July 2023

Objectives:  This study aimed to assess the prevalence of neonatal jaundice and explore associated risk factors in Tikrit City, Iraq.

  Methods: The current study was  a cross sectional study involved 312 neonates (204 of them with jaundice and 108 without jaundice ), attending Salahaddin General hospital from 1st October 2022 to 30th January 2023. The Study sample was convenient . Jaundiced and Non-jaundiced neonates were enrolled into the study when they enter the wards of pediatrics and neonatal intensive care unites in  Salahaddin General Hospital and those visits outpatient clinics of pediatricians and the general population during a free neonatal jaundice screening campaign in Tikrit City.

Results: The prevalence of neonatal jaundice is (9.2%). The most frequent cases was having total serum bilirubin(TSB) level ≤18 milligram/dc liter(mg\dl) (84.8%).The mean ±standard deviation (SD) of hyperbilirubinemia level is (15 ± 3.366 mg\dl ) and  the high TSB level was reported among male gender(58.3%).The percent of preterm babies   was (33.3%) of total sample .The most cases had normal weight (66.7%) at time of delivery ,mean ±SD  of weight is (2698.5±693.54gram) and had no bruises or hematoma as cephalohematoma (89.2%).There was no blood diseases in about (72.5%) of total sample and no history of infection in (68.1%) of cases. The most frequent methods of feeding was breast feeding (39.7%). Regarding to time of appearance of jaundice, the most frequent cases were among those with age group (≤5 days )(89.7%) .The mean±SD  for age of neonate at time of admission is (6.2±3.6 day).

Blood group incompatibility(ABO  incompatibility) was found in (60.8%) of cases with TSB level ≤18 mg/dl and (11.3%) of cases of TSB level <18 mg\dl . While Rhesus incompatibility(Rh incompatibility) was found in (13.2%) of cases with TSB level ≤18 mg/dl .

Conclusion: This study highlights a prevalence of 9.2% for neonatal jaundice in Tikrit City and identifies important risk factors such as blood group incompatibility and preterm birth. Early detection and appropriate management of neonatal jaundice are crucial to prevent potential complications and ensure optimal neonatal care.
Analysis Of The Views of Kiai NU and Muhammadiyah in Bangkalan Madura Regarding The Use of Bitcoin as A Means of Payment of Zakat
Authors: Fatimatus Zahroh  , Mahfiana Layyin
Published: July 2023

This study aims to find out the views of NU and Muhammadiyah kiai in Bangkalan Madura related to  Bitcoin law  and zakat payment law with Bitcoin.  This research was motivated because the pros and cons related to the use of Bitcoin and zakat payments using Bitcoin money until now are still a discussion of scholars until the kiai in Bangkalan Madura also differ in opinion regarding the Bitcoin law, where most of the kiai NU and Muhammadiyah Bangkalan related to  Bitcoin law and zakat law with Bitcoin declare haram, because it contains elements  of  gharar (obscurity ), maysir (gambling), as well as the absence of official regulation from the government. Therefore, zakat with Bitcoin is not allowed. However, there are some scholars who state that the digital money law is halal because digital money like crypto is classified as a "virtual treasure" thus it applies mandatory zakat to Bitcoin money. In addition, there are also differences in regulations between the government and BAPPEBTI,  where the government states in Law No. 7 of 2011 concerning currency that it does not accept payment instruments other than Rupiah, while in BAPPEBTI regulations provide protection for Bitcoin users so as not to feel losses. However, obeying government rules is mandatory.
Relationship Between Symptom Perception and Postprandial Glycemic Profiles in Patients With Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass Surgery
Authors: Tripyla Afroditi , Ferreira Antonio , Schönenberger Katja A. , Näf Noah H. , Inderbitzin Lukas E. , Prendin Francesco , Cossu Luca , Cappon Giacomo , Facchinetti Andrea , Herzig David , Bally Lia
Published: July 2023

OBJECTIVE

Post–bariatric surgery hypoglycemia (PBH) is a metabolic complication of Roux-en-Y gastric bypass (RYGB). Since symptoms are a key component of the Whipple’s triad to diagnose nondiabetic hypoglycemia, we evaluated the relationship between self-reported symptoms and postprandial sensor glucose profiles.

RESEARCH DESIGN AND METHODS

Thirty patients with PBH after RYGB (age: 50.1 [41.6–60.6] years, 86.7% female, BMI: 26.5 [23.5–31.2] kg/m2; median [interquartile range]) wore a blinded Dexcom G6 sensor while recording autonomic, neuroglycopenic, and gastrointestinal symptoms over 50 days. Symptoms (overall and each type) were categorized into those occurring in postprandial periods (PPPs) without hypoglycemia, or in the preceding dynamic or hypoglycemic phase of PPPs with hypoglycemia (nadir sensor glucose <3.9 mmol/L). We further explored the relationship between symptoms and the maximum negative rate of sensor glucose change and nadir sensor glucose levels.

RESULTS

In 5,851 PPPs, 775 symptoms were reported, of which 30.6 (0.0–59.9)% were perceived in PPPs without hypoglycemia, 16.7 (0.0–30.1)% in the preceding dynamic phase and 45.0 (13.7–84.7)% in the hypoglycemic phase of PPPs with hypoglycemia. Per symptom type, 53.6 (23.8–100.0)% of the autonomic, 30.0 (5.6–80.0)% of the neuroglycopenic, and 10.4 (0.0–50.0)% of the gastrointestinal symptoms occurred in the hypoglycemic phase of PPPs with hypoglycemia. Both faster glucose dynamics and lower nadir sensor glucose levels were related with symptom perception.

CONCLUSIONS

The relationship between symptom perception and PBH is complex, challenging clinical judgement and decision-making in this population.
Effect of Human Capital Investment on Income Inequality in Kenya
Authors: Adan Molu A. , Muriithi Dennis K. , Mbaabu Onesmus
Published: July 2023

Human capital investment has a crucial role in economic growth, and as such, it has been regarded as a significant aspect of government spending. The Gini index score reported an average of 41.6 percent in 2018, which is higher than the generally recognized perfect equality Gini index of 20%, suggesting that Kenya has been suffering from high income disparity. There has been a widespread belief that income inequality and human capital investment are mutually exclusive. The theoretical and empirical approaches in the literature provide mixed findings on the relationship. From 1990 to 2019, this study examined the effect of human capital investment on income inequality in Kenya while adjusting for interest rates and GDP per capita. The study adopted a causal research design to determine if a cause-and-effect association between the variables occurs. The time series data were subjected to diagnostic tests to ensure the presumptions of ordinary least squares held. Health expenditure was found to have a negative and statistically significant effect on income inequality after controlling for the interest rate and GDP per capita. After accounting for changes in interest rates and GDP per capita, the result shows that education investment has a negative and statistically insignificant effect on income inequality. The human development index was discovered to have a negative and statistically significant effect on disparity in income which was verified by the robust check. An inverted U was found using the Kuznets test, which was performed to broaden the scope of the research but yielded an insignificant result. The study recommends the formulation and implementation of policies that adhere to the Abuja Declaration on Health, which requires that 15% of government expenditure be allocated to health. The study recommends strict adherence to the 100% transition from primary to post-primary education. The study's conclusions are pertinent to the development and implementation of successful policies that encourage human capital investment, resulting in a decrease in Kenya's levels of income inequality.
Accountability Analysis of Subulussalam City Grants and Social Assistance
Authors: Handayani Alum , Ikhsan Ikhsan
Published: July 2023

This research will discuss accountability in the provision of grants and social assistance in the City of Subulussalam. Accountability is a form of success or failure in carrying out mandatory responsibilities and carrying out tasks through regular accountability media. This research uses a qualitative method with field studies through observation, interviews, and documentation, the reason for choosing this method is because researchers can see firsthand how accountability for grants and social assistance is in the City of Subulussalam. Accountability in the provision of grants and social assistance is seen through indicators of public accountability according to Manggaukung Raba (2006), namely by looking at legitimacy for policymakers, the existence of adequate moral quality, sensitivity, openness, optimal use of resources, efficiency, and effectiveness.
The Importance of Expressing Politeness: English Education Student's Perspectives
Authors: Daulay Sholihatul Hamidah , Azmi Nabilah , Pratiwi Tara
Published: July 2023

This study focuses on how important it is to apply politeness in speaking with someone from the perspective of English Education students. To do this research, researchers used qualitative methods. One of the techniques that researchers use in this study is the non-interactive technique that is the questionnaire. This questionnaire was chosen to explore deeper information about the opinions of English Education Students at State Islamic University of North Sumatera Medan starting from the 2nd â€“ 8th Semester (participants or respondents) on the importance of expressing politeness. Researchers chose the questionnaire technique in order to shorten the time and got more participants rather than had to conduct interviews. This study reports the choice of being polite for people is influenced by differences in power relations, such as notion of status, age, gender, and social distance. This study emphasizes that politeness is needed to be implemented since rudeness creates conflict between one to another person.
La rebelión muladí en al-Andalus y los inicios de la sublevación de 'Umar Ibn Hafsun en las épocas de Muhammad I y al-Mundhir (880-888)
Authors: Marín Guzmán Roberto
Published: July 2023

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Western, Wilda Celia. Alquimia de la nación: nasserismo y poder. México: El Colegio de México, 1997.
Authors: López Villicaña Román
Published: July 2023

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Martínez Montávez, Pedro. El reto del islam: la larga crisis del mundo árabe contemporáneo. Madrid: Temas de Hoy, 1997.
Authors: Gómez García Luz
Published: July 2023

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Margaret M. Pearson. China's New Business Elite: The Political Consequences of Economic Reform. Berkeley-Los Ángeles-Londres: University of California Press, 1997. 207 pp.
Authors: Anguiano Roch Eugenio
Published: July 2023

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Audrey R. Kahin y George McT. Kahin. Subversion as Foreign Policy. The Secret Eisenhower and Dulles Debacle in Indonesia. Seattle & Londres: University of Washington Press, 1995. 318 pp.
Authors: Anguiano Roch Eugenio
Published: July 2023

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REGULASI DIRI, EFIKASI DIRI DAN PROKRASTINASI SANTRI PONDOK PESANTREN AL-IMAM ASHIM MAKASSAR DALAM MENGHAFAL ALQURAN
Authors: Sulaiman Abdul Rajab , Saprin  , Wahyuni Ismail
Published: July 2023

Penelitian ini bertujuan untuk mengetahui tingkat hubungan self-regulation dan self-efficacy dengan prokrastinasi akademik dalam menghafal Al-Qur'an santri Pesantren Al-Imam Ashim Makassar. Jenis penelitian yang digunakan adalah ex post facto dengan metode kuantitatif. Dengan jumlah sampel 51. Instrumen yang digunakan adalah kuesioner. Analisis data menggunakan teknik statistik deskriptif dan inferensial sederhana dan berganda. Hasil penelitian menunjukkan rata-rata tingkat self-regulation sebesar 60,7 dan berada pada kategori interval kelas baik. Nilai rata-rata pada tingkat efikasi diri adalah 37,05 dengan kategori sedang. Nilai rata-rata pada tingkat prokrastinasi adalah 37,62 dengan kategori rendah. Hasil analisis regresi sederhana dan berganda menandakan ada hubungan antara self-regulation dengan self-efficacy, dengan nilai r-hitung lebih besar dari r-tabel yaitu  0,358 dan 0,279 dengan signifikansi 0,05, selanjutnya hubungan yang berlawanan antara self-efficacy. regulasi dan penundaan. Nilai uji hipotesis r-hitung lebih kecil dari r-tabel yaitu -0,470 dan 0,279 dengan signifikansi 0,003 < 0,05. Kemudian hubungan antara self-efficacy dan penundaan yang berlawanan. Nilai uji hipotesis rhitung = -0,665 rtabel = 0,279 dengan signifikansi 0,001 < 0,05 maka diterima. Ada hubungan antara regulasi diri, efikasi diri secara bersama-sama dengan prokrastinasi, dengan nilai 0,529 dengan signifikansi 0,000 < 0,05. Implikasi dari penelitian ini adalah prokrastinasi santri dalam menghafal Al-Quran di Pondok Pesantren Al-Imam Ashim Makassar dapat ditekankan dengan meningkatkan self-regulation berdasarkan teori yang dikaji dalam penelitian ini. Kemudian prokrastinasi santri dalam menghafal Al Quran di Pondok Pesantren Al-Imam Ashim Makassar, juga dapat ditekankan dengan peningkatan efikasi diri berdasarkan teori yang dikaji dalam penelitian ini