bluuebunny/crossref_metadata_2025 huggingface dataset:
Future-proofing the city: A human rights-based approach to governing algorithmic, biometric and smart city technologies
Authors: Wernick Alina , Artyushina Anna
Published: April 2023

While the GDPR and other EU laws seek to mitigate a range of potential harms associated with smart cities, the compliance with and enforceability of these regulations remain an issue. In addition, these proposed regulations do not sufficiently address the collective harms associated with the deployment of biometric technologies and artificial intelligence. Another relevant question is whether the initiatives put forward to secure fundamental human rights in the digital realm account for the issues brought on by the deployment of technologies in city spaces. In this special issue, we employ the smart city notion as a point of connection for interdisciplinary research on the human rights implications of the algorithmic, biometric and smart city technologies and the policy responses to them. The articles included in the special issue analyse the latest European regulations as well as soft law, and the policy frameworks that are currently at work in the regions where the GDPR does not apply.
Characterization of crude saponins from stem bark extract of Parinari curatellifolia and evaluation of its antioxidant and antibacterial activities
Authors: Halilu Emmanuel Mshelia
Published: April 2023

Saponins are surface active glycosides which occur in plants as one of the secondary products of primary metabolism. Saponins have been reported to demonstrate antimicrobial, antioxidant and other biological activities. This study was designed to characterize the crude saponins extracted from stem bark of Parinari curatellifolia and to study the antibacterial and antioxidant activities. The saponin was extracted using standard protocol and was subjected to physicochemical characterization. Foaming and haemolysis tests as wells as determination of foaming index were conducted to confirm the presence of saponins. The solubility of the crude saponins was tested in various organic solvents at room temperature. The nature of the aglycone moiety was identified using Salkowski’s and Liebermann–Burchard’s tests. The glycone moiety was identified using Fehling’s test. Fluorescence test was conducted using UV light at 254 and 366 nm. The TLC separation profile was determined in suitable solvent system. The saponin was subjected to UV and FTIR finger printings using standard methods. Silver nanoparticles were synthesized and characterized using standard method. The saponins were evaluated for antioxidant and antibacterial activities using standard procedures. The foaming index was found to be 1666.6. The crude saponin showed different degrees of solubility in the solvents tested and was found to be highly soluble in methanol, ethanol and DMSO. Generally, the saponins were found to be insoluble in non-polar solvents. The aglycone moiety was found to be triterpenoidal in nature and the glycone was found to be a reducing sugar. The crude saponin produced fluorescence at 254 nm which indicated the presence of some chromophores. The TLC showed the presence of some metabolites with varying Rf values. The UV analysis revealed two absorption peaks at 480 nm and 580 nm. The FTIR finger printing showed absorptions characteristic of some functional groups at different frequencies. The crude saponin and silver nanoparticles demonstrated free radical activity against DPPH free radical with IC50 of 5.878 mg/mL and IC50 0.2477 mg/mL, respectively while the H2O2 radical had IC50 of 5.750 mg/mL. The saponin inhibited the growth of Staphylococcus aureus with zone diameter of inhibition between 2 and 3 mm. The saponins are triterpenoidal in nature and demonstrated antioxidant and antibacterial activity.
Study of the matrix composition effect on gamma spectrometry analysis using Monte Carlo simulation: application for soil to crop transfer factor determination
Authors: Bengroun Maroua , Azbouche Ahmed , Amrani Naima
Published: April 2023

Self-absorption effect has a significant impact on gamma spectrometry measurement for the highly precise determination of the radionuclides activity. Among the main factors affecting the self-absorption effect especially at low gamma energies is the matrix composition of the sample. For this purpose, we studied the matrix composition effect on the self-absorption correction for plant and soil matrices using a Monte Carlo simulation model, composed of High Purity Germanium (HPGe) detector and a cylindrical geometry source. The simulated configuration model was validated by comparison of simulated full energy peak efficiency (FEPE) values with the experimental ones using a standard radioactive solution, covering large interval gamma energies in the range of 59.54–1836.12 keV. The results show that the FEPE values of low gamma energies are affected by the matrix composition, where in the soil matrix the FEPEs decreased by 36% and only by 1% in the plant matrix. The Monte Carlo results were applied in order to accurately calculate the transfer factor of the environmental radionuclides 226Ra, 232Th and 40K from soils to several crops, mustard, artichoke and fennel through their specific activities.
Decision Support for Managing Conservation Seed Bank Collections: Comparing Germination and Viability
Authors: Hoyle Gemma L. , Hodges Joshua A. , Clinton Brook , Tooth Rhys , Neeman Teresa , Guja Lydia K.
Published: April 2023

Without knowledge of seed germination requirements, conservation seed bank collections cannot be utilised, nor their viability monitored over time. When germination is low, deciding whether to invest further seed, time and resources into investigating why can be difficult. We investigated the germinability of 37 grassy ecosystem seed bank collections, including germination response to fire-related cues. Where germination was < 75% we investigated seed viability using the tetrazolium chloride (TZ) staining test. Germination and TZ test results were then compared to determine next steps in collection management. Using 95% confidence intervals of the difference between germination and viability, the 37 collections were assigned to one of seven different data- informed management decisions. This approach provides a detailed decision support framework for conservation collection management, to strengthen current guidelines and ensure that time and resources are effectively allocated. Other seed banks could customise this approach depending on the number of seeds used in testing and what percentage of germination is considered sufficient.
The Effect of Problem-based Learning through Blended Learning on Digital Literacy of Eleventh-Grade Students on Excretory System Material
Authors: Yustina Y. , Mahadi I. , Daryanes F. , Alimin E. , Nengsih B.
Published: April 2023

This study aims to analyze students’ digital literacy through problem-based Learning (PBL) through Blended Learning (BL). The research was carried out in the eleventh grade of SMA Negeri Plus Riau in the even semester of the 2021/2022 academic year. This research is quasi-experimental, using a closed questionnaire with 4 Linkert scales. The research parameter is students’ digital literacy with eight indicators: Functional Skills and Beyond, Creativity, Collaboration, Communication, The Ability to Find and Select Information, Critical Thinking and Evaluation, Cultural and Social Understanding, and E-Safety. Data were obtained using the Linkert scale and converted into Value (N). Value every aspect is the score obtained from the answer indicators that are checked (considered the most appropriate) and divided by the maximum score multiplied by 100. The average value of each aspect is obtained from the total value of each indicator divided by the number of indicators, then analyzed descriptively and qualitatively. Digital literacy students in the control class got an average score of 77.5 (good category) and 85.25 in the experimental class (very good category). Of the eight indicators, the highest digital literacy indicator in the control and experimental classes is creativity, with scores of 85 and 88, respectively. The E-Safety indicator scores 85 and 90. The lowest score was the Critical Thinking and Evaluation indicator, in the control and experimental classes, with a 75, categorized as good. Problem-based learning model through blended learning positively affects the digital literacy of eleventh-grade students of SMA Negeri Plus Riau on the excretory system material.
Problem-based Interactive Physics E-Module in Physics Learning Through Blended PBL to Enhance Students' Critical Thinking Skills
Authors: Sujanem R. , Putu Suwindra I. N.
Published: April 2023

Problem-based interactive physics e-modules (Probinphys), accessed online, were chosen as an alternative method for enhancing high school students’ CTS. This study analyzed the efficacy of the Probinphys E-Module in enhancing high school students’ CTS and described student responses toward the Probinphys E-Module through the Blended-Problem Based Learning (blended-PBL) model. The Probinphys e-module was efficient in enhancing CTS if there was a significant enhancement in student CTS and the minimum average N-gain was in the moderate or consistent category. Student responses toward the Probinphys e-module were in the high category. This research applied one group pretest and posttest group design, involving 79 students in three groups from grade eleven. Before and after learning with the Probinphys E-Module, the three groups of students were given the same CTS test. The collected data were analyzed using Paired-Test, normalized gain (N-gain), and ANOVA. The results show that using the Probinphys e-module in blended PBL efficiently enhances students’ CTS, as indicated by the average N-gain for the three groups in the high category. The average N-gain is the same at 0.5 for the three groups or consistently. Student response toward the Probinphys e-module in blended-PBL is very high.
On the Influence of Patriarch Nikon on the Spread of Orthodoxy in Mordovia (on the Example of a Pre-Restoration Study of the Icon of the Iver Mother of God of 19th Century)
Authors: Syunyaeva-Lobacheva Svetlana K. , Schipina Rimma V.
Published: April 2023

Introduction. The history of the development of the spiritual culture of Mordovia has an inseparable connection with Russia. The article is devoted to the consideration of the historical and cultural aspect in the composition of iconographic studies of the Icon of the Iver Mother of God of 19th century (Fig. 1, 2) as an object of restoration, which is the relevance of research.

Materials and Methods. During the research, the iconographic method was used in combination with the historical and cultural approach.

Results. The results obtained make it possible to learn the history of the existence of the iconographic type of the Icon of the Iver Mother of God, to reveal its religious and cultural role, as well as to trace a number of historical events associated with the missionary activities of Patriarch Nikon in Mordovia, which is the scientific novelty of the publication.

Discussion and Conclusion. The social significance of the study is determined by the focus on the preservation, restoration and popularization of cultural heritage objects as material evidence of historical events related to the development of the spiritual culture of the Mordovian people. Particular emphasis is placed on the significance of this image for Mordovia as the birthplace of Patriarch Nikon. The christening of the Mordovian people contributed to the strengthening of the statehood of the Ponyzovyе region, which developed a spiritual and moral culture.
The Principle of “Dialogic Thinking” by Michael Bakhtin as his Fundamental Methodological Discovery
Authors: Somkin Aleksander A.
Published: April 2023

Introduction. The paper gives the analysis of the work of the outstanding Russian and Soviet philologist and humanist philosopher Mikhail Mikhailovich Bakhtin (1895–1975). The peak of his creative activity falls at the beginning of the 20th century, when he was living in St. Petersburg. Here he spent a lot of time studying the work of representatives of modern Western European philosophy, as well as the works of Russian religious philosophers, gradually forming his doctrine of dialogism.

Materials and Methods. The methodological ground of the study consists of the comparative and historical-philosophical approaches, as well as a systematic approach that allows us to consider the teachings of M. M. Bakhtin on dialogical thinking as an integral system.

Results. A brief review of fundamentally new ideas put forward by M. M. Bakhtin in various areas of socio-humanitarian knowledge – philosophical anthropology, ethics, social philosophy, axiology, cultural studies, literary criticism, linguistics is given. The principle of “dialogical thinking” as the main methodological discovery of M. M. Bakhtin and its philosophical aspects are considered in detail.

Discussion and Conclusion. The originality and novelty of the teachings by M. M. Bakhtin in relation to other authors who also developed the ideas of dialogism are substantiated. The fundamental difference between the concepts of M. Buber and E. Husserl from the teachings of M. M. Bakhtin is shown. For the Russian philosopher the dialogical approach is a megaparadigm and a universal methodological principle of modern socio-humanitarian knowledge.
Intervalo crítico de nitrógeno y época de muestreo en Coffea canephora en suelos Cambisoles
Authors: Pérez-Díaz Alberto , Bustamante-González Carlos , Viñals-Núñez Rolando , Rivera Ramón
Published: April 2023

Introducción. La introducción comercial de Coffea canephora en Cuba ocurrió en 1930. Se han realizado investigaciones sobre los requerimientos de fertilizante nitrogenado, pero no han incluido el análisis foliar como criterio para el diagnóstico del estado nutricional. Objetivos. Establecer los intervalos críticos de los contenidos de nitrógeno foliar y el momento de muestreo más adecuado para proponer correcciones a la fertilización nitrogenada en café. Materiales y métodos. La investigación se desarrolló entre el 2008 y 2011. Se estudió la respuesta del cafeto a dosis de nitrógeno (0, 50, 100, 150, 200 kg ha-1) en un diseño experimental de bloques al azar con cuatro réplicas en suelos del orden Cambisoles. Los muestreos foliares se realizaron en las etapas de floración, fructificación, crecimiento del grano e inicio de maduración. Se determinaron las relaciones entre el rendimiento relativo y las dosis de fertilizante, así como entre las concentraciones foliares de N y el rendimiento relativo. Se estimó el intervalo crítico de contenidos de N (%) que permitió alcanzar de 90 % a 100 % de los rendimientos relativos. Resultados. Los intervalos críticos de nitrógeno (ICN) para rendimientos entre 90 % y 100 %, fueron similares entre años y localidades para la fructificación, aunque variaron entre las etapas fenológicas. Las mayores concentraciones foliares y el intervalo más amplio de estos (2,79–2,97 % N) se encontró en el inicio de fructificación, momento que se consideró más adecuado para corregir el sistema de fertilización empleado. Hubo relación entre los rendimientos relativos de las cosechas anuales y las concentraciones foliares de N para el cafeto robusta. Conclusiones. El intervalo crítico de N foliar en cafeto se estableció en la etapa de fructificación con una concentración de 2,79 %. El muestreo al iniciar la fructificación fue el más adecuado para valorar la corrección de la fertilización nitrogenada.
inovação tecnológica e os desafios representados pela Inteligência Artificial
Authors: Machado José dos Santos , Holanda Francisco Sandro Rodrigues , Bandeira Arilmara Abade , Menezes Adauto Cavalcante , Nogueira Toniclay Andrade , Santos Jane Barbosa , Brilhante Ana Lis Pimentel
Published: April 2023

A Inteligência Artificial (IA) é definida como um amplo ramo da ciência da computação que lida com a construção de máquinas “inteligentes”, capazes de realizar tarefas que normalmente requerem inteligência humana e carrega um enorme potencial para novos serviços e produtos. O objetivo do presente estudo foi identificar os principais desafios para a inovação tecnológica apresentados pela utilização da Inteligência Artificial. Foi realizada uma revisão conhecida como Scoping Review, usando critérios do Cochrane Systematic Reviews associados ao PRISMA, na base Scopus e foram identificados 1.391 registros, usando os descritores artificial intelligence, innovation e challenges. Por meio dos métodos de seleção e classificação foram analisados 40 artigos, que sinalizam que as principais áreas da ciência que estão utilizando a Inteligência Artificial como inovação tecnológica são ciência da computação, engenharias e ciências sociais. Os principais desafios encontrados foram; permitir com IA ofertas de inovações autônomas, integrar a tecnologia de IA nas organizações para processos e resultados de inovação digital, falta de especialistas na área de IA e a necessidade de reformulação das leis e regulamentos referentes a IA.
APLIKASI METODE REGRESI LINIER SEDERHANA UNTUK MEMPREDIKSI KEDATANGAN JUMLAH WISATAWAN MANCANEGARA PASCA PANDEMI COVID 19
Authors: KAROMAH BINTI
Published: April 2023

The visits of foreign tourists are quite a concern because they can be used as a source of regional and state economic income. The decline in tourist arrivals in recent years caused by the impact of this pandemic has sufficiently affected the economic cycle in areas that are usually tourist destinations. The purpose of this research is to find out the number of foreign tourist visits in the future so that the authorities can make further decisions. The method used in this research is simple linear regression. The data used in this study is the number of foreign tourists in 2015-2021 coming from the Central Statistics Agency (BPS). From the results of the study it was found that the results of predicting the number of foreign tourists using the simple linear regression method showed increasing results from year to year, namely starting in 2022 there were 29,584,805.
Symbolic capital of the region in the context of the construction of an ethno-cultural brand (case of the Republic of Mordovia)
Authors: Pakshina Iraida , Kalachina Olga
Published: April 2023

The purpose of the article is to identify the cultural and symbolic attributes that form the symbolic capital of the Republic of Mordovia. As part of the study, a representative survey of 384 residents was conducted in accordance with quotas by sex, age, place of residence, as well as a complete survey of the target group — employees of cultural institutions of the Republic of Mordovia (763 people) using an interactive questionnaire on the Google Forms platform.
The study of cultural and symbolic attributes and the main components of the ethno-cultural image is due to the search for competitive advantages of the territory to determine and form the image of the region, taking into account the potential of national cultures. The results of the study made it possible to determine a set of authentic and original meanings and images that ensure fame and cause a stable positive association with Mordovia.
It was revealed that natural-geographical, ethno-cultural and socio-economic components give the republic its uniqueness and recognition. The natural and geographical advantage of the territory is unique natural and recreational resources, favorable geographical position, proximity to the federal center and the presence of a network of high-quality roads of federal and republican significance. The national and cultural identity of the region acts as a resource for generating its positive reputation. The organization of interesting and non-trivial cultural events that attract local and external audiences increases the attractiveness of the republic. The socio-economic advantage of Mordovia is determined by the production of industrial products and food products that have a high reputation among consumers. For the inhabitants of the region, the places of concentration, preservation and promotion of the cultural heritage of the region, located in the regional centers, become important.
The authors confirmed that the Republic of Mordovia has rich intangible assets that make it possible to construct its own unique ethno-cultural brand of the territory.
The influence of online customer reviews on the purchase decision process for handmade products
Authors: Krasnostavskaia Nataliia , Bozhuk Svetlana , Pletneva Natalia , Bocharnikova Aleksandra
Published: April 2023

Studying the behavior of consumers of various goods and services in the offline and online environment is a necessary element of an effective business in any field. Consumer behavior studies provide insight into how the process of making a decision to purchase a product takes place, and also allows you to identify the tools of influence on consumers on the part of manufacturers and sellers. The author presents a review of the literature on the influence of online reviews on customer behavior, and the author also conducted a study to clarify the presence and level of influence of online customer reviews on the purchase decision process for handmade products. Based on the analysis of the literature, the article identifies the factors of online customer reviews that influence the purchase decision process for handmade products: the quality of online customer reviews, the characteristics of online customer reviews and the number of online customer reviews. The quality of online customer reviews is determined by relevance, reliability, understandability, sufficiency, number of words in the online review, usefulness of the online reviews, and enjoyment of the online reviews. The characteristics of online customer reviews are determined by the text, images and rating in the online customer review. The results of the study showed that online reviews, among other sources of information, are considered quite reliable by buyers, online reviews have an impact on the purchase decision process for handmade products. Among the online review quality metrics, the perceived reliability of an online review, the number of words in an online review, and the perceived usefulness of an online review have the biggest impact on the purchase decision process for handmade products. Among the specific characteristics of an online review, the images in the online review are the most influential. The number of online reviews is also one of the important factors influencing the purchase decision process for handmade products. The results obtained are important for developing directions for improving the marketing tools of the master of handmade products.
Validity study of educational technology on gynecological high dose rate (HDR) brachytherapy
Authors: Ximenes Meiriane Lopes , Firmeza Mariana Alves , Rodrigues Andrea Bezerra , Aguiar Maria Isis Freire de , Souza Gabriela Lacerda , Serpa Georgia de Sousa , Oliveira Patrícia Peres de
Published: April 2023

ABSTRACT Objective: to construct and validate an educational booklet on high dose rate gynecological brachytherapy (HDR) for women with gynecologic cancer. Methods: a methodological study, with the construction and validity of a booklet based on the Doak, Doak and Root theoretical-methodological framework. Content and appearance validity was guided by the Delphi technique, by 11 judges, selected using Jasper’s criteria. Afterwards, clinical validity was carried out with the target population. Results: the booklet, built from evidence from an integrative review, validated with judges, obtained an overall CVI of 0.98. After clinical validity with 27 women, it presents 24 sheets with illustrations produced by a graphic designer, subdivided into topics: gynecological system anatomy and gynecological cancer epidemiology, gynecological brachytherapy definition, therapeutic steps, approach to side effects and management, and two pages for notes. Conclusions: the booklet has validity for use in HDR gynecological brachytherapy treatment.
Estudo de validação de tecnologia educativa sobre braquiterapia ginecológica de alta taxa de dose (HDR)
Authors: Ximenes Meiriane Lopes , Firmeza Mariana Alves , Rodrigues Andrea Bezerra , Aguiar Maria Isis Freire de , Souza Gabriela Lacerda , Serpa Georgia de Sousa , Oliveira Patrícia Peres de
Published: April 2023

RESUMO Objetivo: construir e validar uma cartilha educativa sobre braquiterapia ginecológica de alta taxa de dose (high dose radiation-HDR) para mulheres com câncer ginecológico. Métodos: estudo metodológico, com construção e validação de uma cartilha embasada no referencial teórico-metodológico de Doak, Doak e Root. A validação de conteúdo e aparência norteou-se pela técnica Delphi, por 11 juízes, selecionados através dos critérios de Jasper. Após, realizou-se a validação clínica com a população-alvo. Resultados: a cartilha, construída a partir de evidências de uma revisão integrativa, validada com juízes, obteve IVC global de 0,98. Após validação clínica com 27 mulheres, apresenta 24 folhas, com ilustrações produzidas por designer gráfico, subdividida em tópicos: anatomia do sistema ginecológico e epidemiologia dos cânceres ginecológicos, definição de braquiterapia ginecológica, etapas terapêuticas, abordagem dos efeitos colaterais e manejo, e duas páginas destinadas para anotações. Conclusões: a cartilha possui validação para uso no tratamento de braquiterapia ginecológica de HDR.
Construction of educational technology on non-violent communication between health professionals: an experience report
Authors: Adriani Paula Arquioli , Hino Paula , Taminato Mônica , Fernandes Hugo
Published: April 2023

ABSTRACT Objective: to report the construction of an educational technology to promote non-violent communication for health professionals. Methods: an experience report on the development of an educational technology on non-violent communication for health professionals, prepared by members of a social university extension project. The Plan-Do-Study-Act cycle was used as a process or product management procedure. Results: two complete management method cycles were performed. A mini almanac was generated as a final product, which addressed the main elements of non-violent communication, an example of its use in everyday life, hobbies and interspersed activities. Conclusion: educational technology construction (mini almanac) by members of a university extension project was facilitated using the Plan-Do-Study-Act cycle, proving to be a resource for disseminating non-violent communication in health work and promoting a culture of peace.
Construção de tecnologia educacional sobre comunicação não violenta entre profissionais de saúde: relato de experiência
Authors: Adriani Paula Arquioli , Hino Paula , Taminato Mônica , Fernandes Hugo
Published: April 2023

RESUMO Objetivo: relatar a construção de uma tecnologia educacional de promoção da comunicação não violenta para profissionais de saúde. Métodos: relato de experiência sobre o desenvolvimento de uma tecnologia educacional de comunicação não violenta para profissionais de saúde, elaborada por membros de um projeto social de extensão universitária. Foi utilizado o ciclo Plan-Do-Study-Act como procedimento de gestão de processo ou produto. Resultados: foram executados dois ciclos completos do método de gestão. Foi gerado como produto final um mini almanaque, que abordou os elementos principais da comunicação não violenta, exemplo de seu uso no cotidiano, passatempos e atividades intercaladas. Conclusão: a construção da tecnologia educacional (mini almanaque) por membros de um projeto de extensão universitária foi facilitada com uso do ciclo Plan-Do-Study-Act, mostrando-se um recurso de difusão da comunicação não violenta no trabalho em saúde e promoção da cultura de paz.
Avaliação da morbimortalidade e da sobrevida em pacientes portadores de carcinomatose peritoneal submetidos a cirurgia citorretorredutora e quimioterapia hipertérmica intraperitoneal (HIPEC)
Authors: VALLEJO JAIRO SEBASTIÁN ASTUDILLO , QUEIROZ FABIO LOPES DE , LACERDA FILHO ANTÔNIO , FRANÇA NETO PAULO ROCHA , COSTA BRENO XAIA MARTINS DA , PAIVA RODRIGO ALMEIDA , GARCIA SILVÉRIO LEONARDO MACEDO , SILVA SERGIO BOTREL
Published: April 2023

RESUMO O diagnóstico de carcinomatose peritoneal (CP), indica um estágio avançado do câncer e em geral está associado a um mau prognóstico com sobrevida média variando de 6 a 12 meses. A cirurgia citorredutora (CRS) associada à quimioterapia intraperitoneal hipertérmica (HIPEC) tem sido descrita como uma opção de tratamento para os pacientes portadores de CP primária como nos portadores de mesotelioma, ou secundária como em portadores de cancer colorretal ou pseudomixoma, até recentemente considerados sem possibilidade terapêutica. Objetivo: Avaliar os resultados do tratamento de pacientes portadores de CP submetidos a CRS + HIPEC. Foram analisadas as taxas complicações pós-operatórias, mortalidade e a sobrevida desses pacientes. Resultados: Foram incluídos 56 pacientes com CP, submetidos a c CRS + HIPEC, no período de Outubro 2004 a Janeiro 2020. A taxa de mortalidade foi de 3,8% e taxa de morbidade de 61,5%, sendo a ocorrência de complicações significativamente maior quanto maior o tempo cirúrgico (p<0,001). A sobrevida global pela curva de Kaplan-Meyer foi de 81%, 74% e 53% em 12, 24 e 60 meses respectivamente. Já a sobrevida por diagnóstico nos mesmos períodos foi de 87%, 82%, 47% para os pacientes portadores de pseudomixoma e de 77%, 72% e 57% para pacientes portadores de câncer colorretal (Log -RANK 0,371, p=0,543). Conclusão: A CRS + HIPEC é uma opção de tratamento para pacientes portadores de CP primária ou secundária. Embora com taxa de complicações elevadas, pode proporcionar aumento da sobrevida quando comparado com resultados prévios da literatura e em alguns casos até a cura.
Assessing morbidity, mortality, and survival in patients with peritoneal carcinomatosis undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
Authors: VALLEJO JAIRO SEBASTIÁN ASTUDILLO , QUEIROZ FABIO LOPES DE , LACERDA FILHO ANTÔNIO , FRANÇA NETO PAULO ROCHA , COSTA BRENO XAIA MARTINS DA , PAIVA RODRIGO ALMEIDA , GARCIA SILVÉRIO LEONARDO MACEDO , SILVA SERGIO BOTREL
Published: April 2023

ABSTRACT Peritoneal carcinomatosis (PC) indicates advanced stage cancer, which is generally associated with a poor outcome and a 6 to 12 months. Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is an option for treating patients with primary PC, such as mesothelioma, or secondary PC, such as colorectal cancer (CRC) or pseudomixoma. Until recently, such patients were deemed untreatable. Objective: The purpose of this study was to assess the results of CRS + HIPEC in patients with PC. Postoperative complications, mortality and survival rates were evaluated according to the diagnosis. Results: Fifty-six patients with PC, undergoing full CRS + HIPEC between October 2004 and January 2020, were enrolled. The mortality rate was 3.8% and the morbidity rate was 61.5%. Complications were significantly higher in proportion to the duration of surgery (p<0.001). The overall survival rates, as shown in the Kaplan-Meyer curve, were respectively 81%, 74% and 53% at 12, 24 and 60 months. Survival rates according to each diagnosis for the same periods were 87%, 82% and 47% in patients with pseudomixoma, and 77%, 72% and 57% in patients with CRC (log-rank 0.371, p=0.543). Conclusion: CRS with HIPEC is an option for pacients with primary or secondary PC. Although complication rates are high, a longer survival rate may be attained compared to those seen in previously published results; in some cases, patients may even be cured.
The care of the patients with hipoplastic left heart syndrome in places of social and economic vulneability. An ethical analysis
Authors: ROCHA ISAURA ELAINE GONÇALVES MOREIRA , FONSECA FLÁVIA LINS BEZERRA DE SOUZA , SILVA JOSIMÁRIO
Published: April 2023

ABSTRACT The birth of a child means hope and joy, particularly for the parents and the healthcare team. When this child is born with a severe malformation and a poor prognosis, as in the case of hypoplastic left heart syndrome, the scenario is one of great uncertainty and emotional suffering. The role of the health team becomes fundamental for the identification of conflicts of values and for the search for shared decisions that promote the best benefit to the child. When the diagnosis is made during fetal life, it is necessary to develop counseling strategies appropriate to the context of each family. In places with limited care resources, precarious prenatal care and short temporal conditions, the recommended counseling is compromised. Indication of treatment requires technical competence and a detailed analysis of ethical issues, and consultation with institutional clinical bioethics services or commissions is important. The article proposes to address the moral conflicts of two clinical cases and the respective bioethical analysis that involves principles and values in contexts of vulnerability and uncertainty, contrasting two situations where the indication of treatment was based on accessibility to treatment.
A curva de aprendizado da varicocelectomia laparoscópica bilateral: um estudo prospectivo
Authors: BELKOVSKY MIKHAEL , PASSEROTTI CARLO CAMARGO , MAXIMIANO LINDA FERREIRA , OTOCH JOSÉ PINHATA , CRUZ JOSE ARNALDO SHIOMI DA
Published: April 2023

RESUMO Varicocele ocorre em 15% dos homens e em 35% dos homens inférteis. Desde 1992, a correção cirúrgica com varicocelectomia laparoscópica é o padrão ouro para o tratamento de pacientes sintomáticos ou com análise seminal anormal. A curva de aprendizado para esse procedimento frequentemente realizado ainda não foi descrita. No presente estudo, investigamos a curva de aprendizado de um único urologista em treinamento realizando suas primeiras 21 varicocelectomias laparoscópicas usando ferramentas qualitativas e quantitativas para avaliar seu desempenho durante o processo. Nossos resultados mostram que 14 varicocelectomias laparoscópicas bilaterais são suficientes para atingir o platô da curva de aprendizado.
Cessação do tabagismo para doença arterial periférica: protocolo de revisão sistemática
Authors: KURAMOTO DANIELLE AKEMI BERGARA , ZANIN LUIZ FERNANDO SANTETTI , FLUMIGNAN RONALD LUIZ GOMES , FLUMIGNAN CAROLINA DUTRA QUEIROZ , REICHER MARCELLO ERICH , CORREIA REBECA MANGABEIRA , NAKANO LUÍS CARLOS UTA
Published: April 2023

RESUMO Introdução: a doença arterial periférica tem o tabagismo como principal fator de risco vascular evitável. Entretanto, a maioria dos estudos não destaca o tabagismo como principal variável de exposição. Objetivos: avaliar o impacto das intervenções de cessação do tabagismo versus comparador ativo, placebo ou nenhuma intervenção, nos desfechos da doença arterial periférica. Métodos: usaremos o Cochrane Handbook for Systematic Review of Interventions para orientar todo este processo de revisão. Consideraremos ensaios controlados paralelos ou randomizados por cluster (ECRs), quase-ECRs e estudos de coorte. Buscaremos no CENTRAL, MEDLINE, Embase, PsycINFO, LILACS e IBECS. ClinicalTrials.gov e ICTRP serão consultados para ensaios em andamento ou não publicados. Criaremos uma tabela, usando o software GRADE pro GDT, relatando as estimativas de efeito agrupado para os seguintes desfechos: mortalidade por todas as causas, amputação de membro inferior, eventos adversos, distância percorrida, gravidade clínica, permeabilidade secundária do vaso ou enxerto e qualidade de vida. Avaliaremos esses resultados de acordo com as cinco considerações GRADE para avaliar a certeza do corpo de evidências para esses resultados e tirar conclusões sobre a certeza das evidências na revisão.
Smoking cessation for peripheral arterial disease: systematic review protocol
Authors: KURAMOTO DANIELLE AKEMI BERGARA , ZANIN LUIZ FERNANDO SANTETTI , FLUMIGNAN RONALD LUIZ GOMES , FLUMIGNAN CAROLINA DUTRA QUEIROZ , REICHER MARCELLO ERICH , CORREIA REBECA MANGABEIRA , NAKANO LUÍS CARLOS UTA
Published: April 2023

ABSTRACT Background: peripheral arterial disease has smoking as its main avoidable vascular risk factor. However, most studies do not focus on smoking as the main exposure variable. Objectives: to assess the impact of smoking cessation interventions versus active comparator, placebo or no intervention, on peripheral arterial disease outcomes. Methods: we will use the Cochrane Handbook for Systematic Reviews of Interventions to guide whole this review process. We will consider parallel or cluster-randomised controlled trials (RCTs), quasi-RCTs, and cohort studies. We will search CENTRAL, MEDLINE, Embase, PsycINFO, LILACS and IBECS. We will also conduct a search of ClinicalTrials.gov and the ICTRP for ongoing or unpublished trials. Each research step will involve at least two independent reviewers. We will create a table, using GRADE pro GDT software, reporting the pooled effect estimates for the following outcomes: all-cause mortality, lower limb amputation, adverse events, walking distance, clinical severity, vessel or graft secondary patency, and QoL. Conclusions: we will assess these outcomes according to the five GRADE considerations to assess the certainty of the body of evidence for these outcomes, and to draw conclusions about the certainty of the evidence within the review.
DEVENIR UN CUERPO VAGUEANDO: LA EDUCACIÓN Y EL CUERPO EN EL PENSAMIENTO DE TIM INGOLD
Authors: PICH SANTIAGO
Published: April 2023

RESUMEN: El artículo trata del lugar del cuerpo y la educación en el pensamiento del antropólogo escocés Timothy Ingold. Presentamos los principales presupuestos metateóricos del autor, haciendo hincapié en aquellos que son vectores centrales para nuestro argumento: los pares, naturaleza-cultura, cuerpo-mente y animalidad-humanidad. El pensamiento de Ingold es una apuesta en una formación humana referenciada en el devenir, entendida como inserción singular en una tradición que está siempre situada en el plano de la historicidad y de la inmanencia, que no tiene un rumbo predefinido, sino que se constituye en el andar vagueando, a partir de una relación de atención y percepción del mundo mediada por los otros que ya están presentes en él. El cuerpo es concebido como una dimensión constitutiva del ser humano, sin el cual no es posible comprender el modo de estar-siendo-con-los-otros en el mundo, sino que en él se realizan las potencialidades humanas, siendo que la atención y la percepción son cruciales. Al problematizar los desdoblamientos de ese pensamiento para la formación humana y la educación corporal, encontramos potentes herramientas conceptuales para criticar la tradición moderna de educación, bien como para vislumbrar otro modo de concebir la formación humana y la educación corporal, que son entendidas no como una mera transmisión de saberes con los cuales se opera lógicamente, ni como el entrenamiento de un cuerpo material que debe rendir lo máximo posible, sino entendidos como la transmisión de un modo singular de percepción y (re)creación del mundo y como una instancia de crear caminos vagueando, respectivamente.
AS TECNOLOGIAS DIGITAIS COMO RECURSOS PEDAGÓGICOS NO ENSINO REMOTO: IMPLICAÇÕES NA FORMAÇÃO CONTINUADA E NAS PRÁTICAS DOCENTES
Authors: AURELIANO FRANCISCA EDILMA BRAGA SOARES , QUEIROZ DAMIANA EULINIA DE
Published: April 2023

RESUMO: A presente pesquisa emerge de inquietações sobre os impasses que transpassam a experiência do Ensino Remoto Emergencial (ERE), durante a Pandemia da COVID-19 desencadeada em 2020. Neste sentido, este artigo relata acerca de uma pesquisa cujo objetivo foi analisar as implicações do uso das tecnologias digitais no processo de formação continuada e nas práticas dos professores alfabetizadores, durante o ensino remoto, em 2020, na Escola Municipal Francisco Francelino de Moura. O estudo desenvolveu-se mediante revisão bibliográfica dos principais conceitos que fundamentam o processo de alfabetização: mediação pedagógica, prática docente e ERE. Além disso, foram verificados os documentos normativos desse tipo de ensino, a Base Nacional Comum Curricular (BNCC), entre outros. Realizou-se ainda, uma pesquisa de campo de cunho qualitativo com duas professoras alfabetizadoras do 1º e 2º ano (Ciclo de Alfabetização). Utilizou-se como procedimento de tratamento dos dados a Análise de Conteúdo. Constatou-se que as professoras desenvolveram novas práticas, principalmente com o uso das tecnologias digitais e, apesar das dificuldades encontradas, buscaram conhecer e apropriarem-se desses recursos resultando em uma prática reflexiva de constante pesquisa e aperfeiçoamento.
Estudo Sinótico e da Estrutura Vertical de um Vórtice Ciclônico de Altos Níveis Ocorrido em Janeiro de 2016
Authors: Lyra Matheus José Arruda , Arraut Josefina Moraes
Published: April 2023

Resumo Os Vórtices Ciclônicos de Altos Níveis (VCAN) são um dos principais sistemas que provocam alterações no tempo durante a pré-estação chuvosa do Nordeste do Brasil (NEB). O principal objetivo deste estudo é compreender a configuração do VCAN que se desenvolveu durante 26 dias em janeiro de 2016 através da análise sinótica e termodinâmica. Além do vórtice, sistemas de diferentes escalas espaciais e temporais como a Zona de Convergência do Atlântico Sul (ZCAS), Oscilação Madden-Julian (OMJ) se configuraram simultaneamente, junto com o El Niño que se encontrava ativo desde 2015. A conexão entre os sistemas supracitados provocou um grande aumento nos índices de chuva no NEB. A configuração do VCAN em conjunto com a ZCAS sendo impulsionados pela propagação da OMJ determinaram o excesso de chuvas durante os dias analisados. A periferia oeste do vórtice se posicionou próxima à costa leste do NEB, provocando uma alteração no padrão de convergência do transporte de umidade de grande escala, que passou a convergir sobre o NEB, elevando os índices de precipitação em alguns estados. A avaliação da estrutura vertical do VCAN por meio de seções verticais indicou movimentos ascendentes somente na periferia oeste, a periferia leste foi caracterizada por forte inibição convectiva.
Minituber production in yam for alternative vegetative propagation: types of cuttings, substrates, and anatomy
Authors: Santos Crislaine Alves dos , Arrigoni-Blank Maria de Fátima , Gois Itamara Bomfim , Costa Andréa Santos da , Oliveira Sara Dayan da Silva , Blank Arie Fitzgerald
Published: April 2023

ABSTRACT: Yam is a tuber vegetable crop with vegetative propagation. The crop is low yielding due to the difficulty of obtaining quality material for propagation and the high cost of acquisition. The cutting technique is a new alternative for vegetative propagation of yam. The present studyevaluated the production of minitubers of yam through cuttings, and follow the formational growth of the minitubers. Different types of cuttings, obtained from three positions on the shoots, and three substrates were tested. The types of cuttings and substrates did not significantly affect the number of minitubers per cutting, this number ranging from 1.18 to 1.75. The best results were obtained using Tropstrato Florestal® and median-position cuttings for the following variables: minituber length (17.47 mm), minituber diameter (12.63 mm), minituber fresh weight (2.12 g), and percentage of cuttings with two minitubers (75%). Anatomical analysis showed cell divisions and starch accumulation in the nodal region at seven days after planting the cutting. Emergence of the minituber could be observed at 21 days. The production of yam minitubers through stem cuttings is enhanced using cuttings obtained from the median position of the shoot and using the commercial substrate Tropstrato Florestal®.
Risk factors associated with stillbirth in sows
Authors: Sens Junior Vamiré Luiz , Rosa Emanoelle Regina , Fagundes Deivison Pereira , Peripolli Vanessa , Ulguim Rafael da Rosa , Siqueira Bruna Pereira , Messias Hérica da Silva , Bortolozzo Fernando Pandolfo , Bianchi Ivan
Published: April 2023

ABSTRACT: In this study, the risk factors associated with stillbirth in sows were identified and their odds ratio assessed. For this purpose, 587 farrowings on Farm A and 929 on Farm B were monitored, and the sow parity, body condition score, farrowing duration, total number of piglets born, numbers of live births, stillbirths, and mummified piglets, obstetric interventions, and piglet sex and weight were recorded. At the end of farrowing, piglets classified as stillborn were necropsied to confirm the diagnosis. Consequently, 5.49% of the piglets on Farm A and 5.10% of those on Farm B were stillborn. On both farms, sows with a high parity, prolonged farrowing, and a large litter size had the highest odds ratio of stillbirths. On Farm B, farrowing intervention through the use of vaginal palpation and oxytocin increased the odds of stillbirth by 1.7 and 2.5 times, respectively. Heavy litters increased the odds of stillbirth by 1.4 times. Additionally, low-birth-weight piglets were 2.3 and 3.1 times more likely than their medium-birth-weight and high-birth-weight counterparts, respectively, to be stillborn. In conclusion, on both farms, the risk factors associated with stillbirth were a high parity, a large litter size, and prolonged farrowing.
Number of lesions, severity and incubation period of isolates of Corynespora cassiicola in soybean cultivars
Authors: Puia Jacqueline Dalbelo , Hoshino Adriano Thibes , Shimizu Gabriel Danilo , Moreira Ana Maria da Silva , Vigo Sandra Cristina , Canteri Marcelo Giovanetti
Published: April 2023

ABSTRACT: This study checked the severity and incubation period of isolates of Coryneporacassiicola (C.c) in soybean cultivars, as well verified whether the position of leaflets influences the susceptibility of the plant to target spot. The experiment was conducted in randomized block with 8 isolates of C.c and 8 soybean cultivars factorial scheme, with five repetitions each block. The plants were inoculated with suspension from 2x104 conidia mL-1. The number of lesions per leaf and the incubation period (IP) were evaluated. The ISO 4S isolate caused greater number of lesions in plants. BMX Potência RR, BMX Força RR, and NA 5909 RG had the lowest occurrence of lesions, while the cultivar BMX Elite IPRO showed the highest number of lesions. More lesions were detected in the lower leaf compared to the upper leaf of the plants. The longest IP was observed for ISO 4S in both leaflets, while the lowest IP for ISO 1A, 3A and 2A in the lower leaf, and for ISO 11S and 1S in the median leaf. For cultivars, significant difference in IP was observed only in the lower leaf, with the longest and shortest IP detected for BMX Elite IPRO and BRS 284, respectively. In general, the upper leaf of the plants presented the shortest IP while the lower leaf had the longest IP.
Acid resistance of Salmonella Typhimurium ATCC 14028 after desiccation stress during peanut storage
Authors: Pereira André Aquino Mariano , Amorim Neto Dionisio Pedro , Hertwig Aline Morgan von , Maia Rafael Pimentel , Nascimento Maristela
Published: April 2023

ABSTRACT: Salmonella is a relevant pathogen, which causes foodborne outbreaks associated with both high and low moisture foods (LMF). This study evaluated the effect of previous desiccation stress on the acid resistance of S. Typhimurium ATCC 14028 using blanched peanut kernels as an LMF model. Salmonella was recovered from the peanut samples throughout 180 days of blanched peanut kernels storage at 28 ºC. During this period two death rates were verified, 0.04 log cfu/g/day in the first 30 days and 0.007 log cfu/g/day between 30 and180 days.Regarding acid resistance, there was no difference (P > 0.05) in the Salmonella growth/death kinetics between the undesiccated sample (TSB)and the cells recovered from peanut samples over 180 days of storage after 4 h at pHs 3.0, 3.5, 4.5 and 7.2. The average growth rate observed for pH 7.2 was 0.44 log cfu/ml/h. At pH 4.5, the Salmonella counts did not change significantly over 4 h. In contrast, Salmonella populations declined by 0.14 to 0.29 log cfu/ml/h at pH 3.5. At pH 3.0 declines were estimated to be 0.65 log cfu/ml/h for the undesiccated sample and 2.07 log cfu/ml/h for Salmonella recovered from peanuts stored for 120 days. Therefore, our data indicated that desiccation stress caused during the peanut storagedid not influence the Salmonella acid resistance.