bluuebunny/crossref_metadata_2025 huggingface dataset:
INOVAÇÕES TECNOLOGICAS ALIADAS À EDUCAÇÃO E OS DESAFIOS DOCENTES EM SALA DE AULA
Authors: SACRAMENTO VIVIAN CRISTINA BRAVO
Published: September 2023

O presente texto tem como objetivo verificar como a nova tecnologia aliada à educação e como os desafios docentes está sendo integradas à prática pedagógica. Por fazer parte do mundo moderno notamos que as escolas atualmente usam estas ferramentas no processo ensino-aprendizagem. Por isso, o ensino não pode descuidar da investigação voltada para a realidade que os docentes estão inseridos, porque são estes elementos que serão determinantes para modificar a ação dos mesmos. Neste estudo serão realizadas pesquisas bibliográficas, buscando desta forma, descrever e conceituar os recursos tecnológicos disponíveis no ambiente escolar, sua utilização e a importância dos mesmos neste contexto.
Corn biochar influences yield attributes of two varieties of chili (Capsicum annuum) in the coastal region
Authors: Faria Naznin  , Riad Mahmud  , Tasnova Tasin  , Md. Nahid Hashan  , kazi Rukiya  , Rafat Nur Abdullah Khan
Published: September 2023

A solid biomass pyrolysis byproduct is biochar. The most important uses of this carbon-rich, porous substance are soil enhancement, remediation, and pollution management. Biochar improves soil fertility, water retention, and fertilizer efficiency. Biochar stores plant nutrients, reduces salinity and drought, and neutralizes soil acidity. This component is environmentally favorable. It reduces chemical fertilizer and irrigation as well as lowers farmer costs. Green chili benefits greatly from organic fertilizer. Biochar must pay more attention to this economically valued crop despite its importance. Under a randomized complete block design (RCBD) with 3 replications, a field experiment determined the best dose to boost chili plant yield. Thus, to determine how two green chili varieties—Bangladeshi local hybrid 'Anal 1701 DG F1' (V1) and Indian hybrid 'Bijlee Plus F1' (V2)—react to different corn biochar doses. The treatments included T1 (Control), T2 (0.1kg/m2), T3 (0.3kg/m2), T4 (0.5kg/m2), and T5 (0.7kg/m2). Using biochar significantly (*p<0.05) increased yield characteristics. Bijlee plus F1 had the highest yield and yield-related parameters above Anal 1701 DG F1. The combination of treatments and varieties yielded the maximum (2.40 ton/ha) in T5V2, while the lowest (0.3134 ton/ha) was in T1V1. Most yield-related characteristics (fruit number per plant, single fruit weight, mature chili length, diameter, and total yield) were achieved from T5 treatment and T5V2 interaction. Corn biochar performed well on green chili varieties and yield-related parameters. The investigation proposed using Bijlee plus F1 variety and 0.7kg/m2 corn biochar (T5) dose to maximize chili production. This is an excellent recommendation for the farmers of coastal areas.
A Reasoning of Xunzi’s (荀子) State Governance Ideas: A Case Study on The Theory of Human Nature (Xing性)
Authors: BEDEL Burçin
Published: September 2023

Xunzi was a Chinese thinker who lived in the period of Warring States (480/403-222 BCE). He was critical of philosophical ideas in his time and brought forward ideas for establishing and preserving order in society. He created a state governance system in which rituals (li 禮) and law (fa 法) worked together. He reasoned his ideas on state governance and theories about an ideal society on his theories of human nature, and he has been criticized for his negative attributions to it. However, in the book bearing his name, Xunzi, it is seen that there are different presentations of his views on human nature. This article presents these different perspectives on Xunzi’s theory of human nature and shows why he attributed negative qualities to it. It offers a better understanding of the character of his theories, in this way, enlightens the way to a better understanding of his state governance ideas.
THE EFFECT OF THE PREPARATION "RIBAV-EXTRA" ON THE DEVELOPMENT OF BLACKBERRY PLANTS OF THE FREEDOM VARIETY DURING ADAPTATION
Authors:   Federal State Budget Scientific Institution «North Caucasian Federal Scientific Center of Horticulture, Viticulture, Wine-making», Krasnodar, Russia, EGOROVA O.V. , AMOSOVA M.A. ,   Federal State Budget Scientific Institution «North Caucasian Federal Scientific Center of Horticulture, Viticulture, Wine-making», Krasnodar, Russia
Published: September 2023

The paper presents data on the use of the growth regulator “Ribav-Extra” at the stage of blackberry adaptation. Blackberry microplants of the Freedom variety have a high adaptive capacity. In the variant with “Ribav-Extra”, 98 % of plants adapted, in the control variant - 95 %. It has been established that treatment with a growth regulator promotes the development of the plant root system. After treatment with the preparation, 10 roots or more were formed on the plant, in the control variant, on average, 4-5 roots were formed on the plant. The bulk of the roots had a length of more than 4 cm (up to 7 cm), in the control variant 2-4 cm.
CHANGE IN THE QUALITY OF CHARDONNAY GRAPE SHOOTS DEPENDING ON THE ROOTSTOCK IN THE CONDITIONS OF THE CENTRAL ZONE OF THE KRASNODAR REGION
Authors:   Federal'noye gosudarstvennoye byudzhetnoye obrazovatel'noye uchrezhdeniye vyssheye obrazovaniye «Kubanskiy gosudarstvennyy agrarnyy universitet imeni I.T. Trubilina», KUSTOV T.A.
Published: September 2023

The article presents a study of the influence of various rootstocks on the change in the quality of cuttings of Chardonnay grape variety in the conditions of the Central zone of the Krasnodar region. In the course of the research, the following calculations and observations were carried out: the average diameter of the shoot and core, the cross-sectional area of the shoot, core and wood, as well as the aging coefficient and the conditional aging coefficient were determined. Compliance with the quality standards of cuttings of the Chardonnay variety, depending on the rootstock, was determined using the aging coefficient in accordance with GOST 28181-89, as well as using the conditional aging coefficient according to the method of Prof. N.V. Matuzok. Scion-rootstock combinations with the best indicators of maturation in the conditions of the central zone of the Krasnodar region were identified.
THE EFFECTIVENESS OF ACARICIDE SHANSITEK, EС IN THE CONTROL OF FRUIT TREE RED SPIDER
Authors:   Federal State Budget Scientific Institution «North Caucasian Federal Scientific Center of Horticulture, Viticulture, Wine-making», Krasnodar, Russia, KIEK D.A. , PODGORNAYA M.E. ,   Federal State Budget Scientific Institution «North Caucasian Federal Scientific Center of Horticulture, Viticulture, Wine-making», Krasnodar, Russia, KOVALEVA A.I. ,   Federal State Budget Scientific Institution «North Caucasian Federal Scientific Center of Horticulture, Viticulture, Wine-making», Krasnodar, Russia
Published: September 2023

Under the influence of weather and climatic conditions, the harmfulness and spread of the fruit tree red spider Panonychus ulmi Koch increases. The early release of imago in 2023 was already noted in the third decade of May. The article presents data on a decrease in the number of fruit tree red spider in the Prikuban zone of the central subzone when using the preparation Shansitek, EC (Abamectin,18 g/l) 1 l/ha and Apollo, SC (Clofentesin 500 g/l) 0.6 l/ha.
AFYONKARAHİSAR MİLLETVEKİLİ RUŞEN EŞREF (ÜNAYDIN) BEY’İN KURUCU MECLİS’TEKİ FAALİYETLERİ (1923-1927)
Authors: ÖNGEL Çağlar
Published: September 2023

1918 tarihinde İtilaf Devletleri’nin Anadolu’yu işgal etmesiyle birlikte Milli Mücadele dönemi başlamıştır. 1921 yılının Ocak ayında itibaren ise Türk İstiklal Harbi dönemi başlayarak 11 Ekim 1922 tarihinde Mudanya Ateşkes Antlaşması’na kadar sürmüştür. Türkiye Cumhuriyeti’nin tapusu niteliği taşıyan Lozan Barış Antlaşması ise 24 Temmuz 1923 tarihinde imzalanmış ve 23 Ağustos 1923 tarihinde kurucu meclis olarak nitelendirilen milletvekillerinin oylamasıyla kabul edilmiştir. İşte bu meclis içerisinde yer alan milletvekillerinden birisi de Ruşen Eşref Ünaydın’dır. Ruşen Bey, genellikle edebi yönüyle bilinmektedir. Kendisi, birçok gazetede yazılar yazmış, kitaplar çıkarmıştır. Özellikle Milli Mücadele dönemini kalemiyle desteklemiştir. Eşref Bey, üç dönem Afyonkarahisar milletvekilliği yapmıştır. Milletvekilliği 1933 tarihinde sonra erince Dil komisyon üyeliği, Türk Dili Tetkik Cemiyeti görevlerinde yer almıştır. Tiran, Atina, Budapeşte, Roma, Londra büyükelçiliklerinde çalışmıştır. Bu çalışma, Ruşen Eşref Bey’e ait bilgilerde bu zamana kadar ele alınmamış, Cumhuriyetin ilk milletvekillerinden birisi olması münasebetiyle, meclisteki yaptığı faaliyetler ele alınacaktır. Ruşen Bey’in kurucu meclisteki konuşmaları, katıldığı oylamalar, itiraz ettiği konular, üzerinde durduğu ve ısrarcı olduğu hususlar hakkında bilgi verilecektir.
Pinna Edge Biopsy of 7 and 21 Day Old C57BL/6 Mice as a Method for Identification and Genotyping
Authors: Chen Diane D , Molk Denise M , Palley Lori S , Jarrell Donna M
Published: September 2023

Identifying and genotyping mice prior to weaning can be useful for mouse colony management. Mice of an undesired genotype can be identified prior to weaning and removed from further study, resulting in a reduction of housing costs, and labor time. We hypothesized that a pinna edge biopsy
(PEB) performed by removing a portion of its edge with scissors is a reliable method for identifying and genotyping mice on postnatal day (PND) 7 consistent with PND 21, weaned mice. The pinnae of 54 C57BL/NCrl6 mice were biopsied on PND 7, and another 54 were biopsied on PND 21. Nine
pinna patterns were tested. The accuracy of pattern identification was assessed on PND 7, 14, 21, 30, and 63. The mean times were compared for performing the biopsy on PND 7 and PND 21 mice, and the average time taken to identify the patterns were determined. Weight, milk spot presence, pup
rejection, morbidity, and mortality were examined at various time points. During the biopsy, bleeding of the pinna, urination, vocalization, and flinching were assessed. No significant differences were detected in DNA quality, relative DNA quantity, genotyping reliability, or body weight (P
≥ 0.05) between mice biopsied on PND 7 and PND 21. Flinching at the time of PEB was significantly higher in PND 21 mice as compared with PND 7 mice (P < 0.00001). Pinna pattern identification accuracy for mice biopsied on PND 7 and PND 21 were 96% and 98%, respectively.
This study validates the use of PEB for simultaneous identification and genotyping of PND 7 mice.
Green Digital Twins in the Product Life Cycle
Authors: Deuse Jochen , Wagstyl David , Hernandez Moreno Victor , Polikarpov Mikhail , Wöstmann René , Hoffmann Florian
Published: September 2023

Reducing emissions from industrial processes is crucial for global cli-mate protection goals. Many countries have set ambitious targets, such as Germany's goal to reduce industrial emissions by 20% before 2030. To achieve these goals, innovative technologies for sustainable industrial production are needed. Digital technologies offer opportunities to analyze energy and resource consumption, leading to data-driven improvements that contribute to climate protection. The demand for traceability solutions, including product carbon footprints and digital product passports, has increased due to EU regulations. Digital technologies have emerged as powerful enablers to meet this demand. Green Digital Twins, which optimize energy efficiency, minimize carbon emissions, and reduce environmental impact, provide a technological solution for sustainable transformation. While digital twins have gained traction in the industrial environment through standardization and demonstration activities, the technological impact throughout the product life cycle have not been adequately considered. This research paper explores how green Digital Twins contribute to sustainable industrial production throughout the product life cycle. The findings highlight opportunities and challenges in revealing emissions and constructing green Digital Twins for various purposes, thereby contributing to climate protection targets. Jochen Deuse (1, 2), WagstylDavid (1), Victor Hernandez Moreno (2), Mikhail Polikarpov (1), René Wöstmann (1), Florian Hoffmann
FACTORS INFLUENCING TOURIST SATISFACTION WITH AGRITOURISM IN THE MEKONG DELTA, VIETNAM
Authors:   Faculty of Business Administration, University of Economics, University of Danang, Da Nang, Vietnam, SON Nguyen Truong , NGUYEN Quoc Nghi ,   School of Economics, Can Tho University, Can Tho, Vietnam, HOANG Thi Hong Loc ,   School of Economics, Can Tho University, Can Tho, Vietnam
Published: September 2023

The Mekong Delta, Vietnam possesses great potential and advantages for developing agritourism. To ensure the sustainable development of agritourism, enhance service quality, and improve tourist satisfaction are essential. This study aims to identify the factors influencing tourist satisfaction with agritourism in the Mekong Delta. Data were collected using a quota sampling method, with a sample size of 228 tourists who had visited and experienced agritourism in the Mekong Delta, Vietnam. A mixed-method approach combining qualitative and quantitative research was used to test research hypotheses. By applying structural equation modeling (SEM), the study demonstrated that local culture, natural landscape, novelty, assurance, tourism human resources, and perceived value positively influenced tourist satisfaction with agritourism in the Mekong Delta. Among these factors, the natural landscape had the most impact on tourist satisfaction with agritourism in the Mekong Delta.
SPATIAL REGRESSION MODEL OF URBAN WALKABILITY UNDER THE 15-MINUTE CITY APPROACH
Authors:   Universidad Nacional de Colombia, Sede Manizales. Facultad de Ingeniería y Arquitectura, Departamento de Ingeniería Civil, Grupo de Investigación en Movilidad Sostenible, Manizales, Colombia, ARISTIZÁBAL Juan E. , SARACHE William ,   Universidad Nacional de Colombia, Sede Manizales. Facultad de Ingeniería y Arquitectura, Departamento de Ingeniería Industrial, Manizales, Colombia, ESCOBAR Diego A. ,   Universidad Nacional de Colombia, Sede Manizales. Facultad de Ingeniería y Arquitectura, Departamento de Ingeniería Civil, Grupo de Investigación en Movilidad Sostenible, Manizales, Colombia
Published: September 2023

The 15-minute city aims to decentralize the urban economic poles to provide local services to its entire population. The objective of this research is to geographically determine the economic poles in an intermediate Latin American city and evaluate their geospatial coverage. This research develops a geographic accessibility model to analyze the spatio-temporal distribution of the economic poles, considering the socioeconomic stratum of households in Manizales (Colombia). Moreover, we apply a spatial regression model of pedestrian trips. Results show that proximity to urban economic poles is directly correlate with pedestrian trips. In Manizales, only 35.8% of the population reaches its closest economic pole within a 15-minute walk; moreover, accessibility inequities mainly affecting lower-income families were detected. The 15-minute city approach poses a high potential to contribute to urban spatial justice to the extent that urban planners facilitate the growth of economic activities and services in neighborhoods, with special attention to the less privileged.
THE EPISTEMOLOGICAL VALUES OF TRAVEL & TOURISM COMPETITIVENESS INDEX AND ITS PREDICTIVE POWERS ON TOURIST ARRIVALS IN AFRICA; PLS-SEM APPROACH
Authors:   Aksum University, Department of Tourism Management, Institute of Archaeology and Tourism, Aksum, Tigray, Ethiopia, HIYAB Weldearegay G. , HASSAN Thowayeb H. ,   Social Studies Department, College of Arts, King Faisal University, Al Ahsa, Saudi Arabia, HASSANIN Mostafa A. ,   Mass Media Communication Department, College of Arts, King Faisal University, Al Ahsa, Saudi Arabia, ALMAKHAYITAH Muhanna Yousef ,   Social Studies Department, College of Arts, King Faisal University, Al-Ahsa, Saudi Arabia
Published: September 2023

This study aimed to assess the explanatory power of the sub-indices and pillars of the Travel & Tourism Competitiveness Index on ITA taking Africa as a case. The study extended the epistemological articulations and empirical values of the TTCI by introducing ITA as a dependent variable. It took WEF's 7 years report on TTCI of 29 African economies. Results show that the predictive powers of half of TTCI Sub-indices as formative indicators to ITA are weak and negative. Analogously, the collinearity, validity, and reliability issues of sub-indices were substantially not resolved. These findings have implied that the TTCI has to articulate its predictive bearing before it can be accepted as an epistemologically and practically relevant concept that prescribes policy issues especially on the course of diagnosing the African Tourism ecosystem.
Opportunities and Prospects for Preclinical Drug Safety Assessment Using Alternative Methods: Experience from the Toxicology in the 21st Century (Tox21) Programme in the USA
Authors: Perfilova V. N.
Published: September 2023

SCIENTIFIC RELEVANCE. The Tox21 (Toxicology in the 21st Century) programme was developed by the US Tox21 Consortium with the aim to replace animal-based toxicity assessments of chemicals with a wide range of in vitro and in silico testing approaches and has since been successfully applied in practice.

AIM. The study aimed to review information on alternative in vitro models developed as part of the Tox21 programme for testing the toxicity of chemical compounds.

DISCUSSION. According to the information provided by the National Toxicology Program, Environmental Protection Agency, National Center for Advancing Translational Sciences, and other Tox21 Consortium members on their official websites and in the literature, the Tox21 Consortium has developed a quantitative high-throughput screening technology for testing the safety of chemicals and created the Tox21 10K library of chemical compounds using this screening technology. The library has been successfully used to create models that predict the toxicity of chemicals prior to preclinical studies. Researchers have proposed new approaches to studying the safety of chemical compounds in human cell lines to replace in vivo studies. Innovative organ-on-chip, multi-organ-on-chip, and organoid models are free from the drawbacks and limitations of cell-line models and offer more accurate representations of complex cell–matrix and organ–organ interactions. Developed under the Tox21 programme to search for new chemical toxicity biomarkers and gene signatures, novel transcriptomics (toxicogenomics) technologies can be used to classify toxicants according to their health risks and to identify potential side effects long before discovering any pathological changes in the body. The Interagency Coordinating Committee on the Validation of Alternative Methods conducts technical evaluation of alternative testing methods and promotes their implementation into regulatory practice.

CONCLUSIONS. Thus, new tools and technologies provide an opportunity for switching from in vivo toxicity testing of candidate medicinal products to in silico and in vitro methods.
Manajemen Kinerja Sumber Daya Manusia di Kantor Wilayah Kementerian Agama Provinsi Sulawesi Tengah
Authors: Langke Rusman
Published: September 2023

Manajemen kinerja merupakan suatu proses yang dilakukan untuk keberhasilan organisasi dalam mencapai tujuan organisasi. Untuk memotivasi para pegawai untuk dapat memiliki motivasi kerja yang tinggi maka diberikan kompensasi dengan imbalan yang memadai sesuai kinerja yang dilakukan, mengikutsertakan dalam pendidikan dan pelatihan yang relevan bidang tugasnya, menciptakan iklim kerja yang kondusif agar nyaman dalam melaksanakan kerja dengan penuh komitmen. Tujuan penelitian untuk mengatur kinerja dengan lebih terstruktur dan terorganisir, mengetahui seberapa efektif dan efisien suatu kinerja, membantu dalam penentuan pengambilan keputusan, meningkatkan kemampuan dan mendorong para pegawai Kementerian Agama di Provinsi Sulawesi Tengah untuk meningkatkan kinerjanya. Rancang bangun suatu organsasi dibutuhkan manajemen melalui langkah-langkah atau tahapan untuk mencapai tujuan organisasi yang efektif dan efesien. Tahapan yang dimaksud adalah (1) Directing/planning terhadap target yang akan dicapai dengan memperhatikan prinsip SMART (Measureable, Achievable, Realistic, dan Timebound); (2) Managing/supporting yang berfokus pada manage, dukungan, dan pengendalian terhadap jalannya proses agar tetap berada pada jalurnya; (3) Review/appraising terhadap kinerja yang telah dilaksanakan; dan (4) Developing/ rewarding yang berfokus pada pengembangan dan penghargaan, (5) Timebound dengan menentukan batas waktu pekerjaan diselesaikan sesuai rencana kerja
Penerapan Metode Hill Al-Musykilah Pada Pembelajaran Maharah Al-Kalam Siswa Madrasah Aliyah
Authors: Masitoh Harum , Nur Mufidah Luk-Luk , Nurhayati Anin
Published: September 2023

Arabic is a subject that must be presented within the scope of madrasah learning. Arabic consists of 4maharah(skills), andmaharahwhich is considered the most important ismaharah al-kalam(speaking skills). Madrasa students are expected to be able to apply Arabic in the school environment. However, the majority of Aliyah madrasah students are embarrassed to express themselves using Arabic during learning. They tend to be rigid and are not used to expressing feelings and ideas in Arabic orally. To overcome this problem, teachers should choose and use the right method for learning Arabic, in particularmaharah al-kalam. The many and varied Arabic language methods must be adapted to the abilities and conditions of the students. In this article, the author will focus on discussing the application of the methodhill al-musykilat(problem solving) in learningmaharah al-kalam. This method is considered appropriate if applied to Aliyah madrasah students. With reasons, learning objectivesmaharah al-kalamcan be achieved with this method. As for one of the goals is that students are able to think and analyze problems, and express answers using Arabic orally in accordance with the problems that have been presented previously.
Lock-in vs. Institutional Blockage: Lost in Translation
Authors:   Institute of Economics of the Russian Academy of Sciences, Vernikov A. V. , Kurysheva A. A. ,   Southern Federal University
Published: September 2023

In this article, we explore a well-known concept that explains how institutions can become deeply ingrained in a community, so that it becomes difficult to remove, even if most people consider them ineffective. This phenomenon can occur when institutions emerge by chance or are intentionally implemented. In English, this phenomenon is referred to as “lock-in”, but in Russian it has been inaccurately translated as blokirovka (literally “blockage”). This Russian word, however, conveys the opposite meaning, referring to the rejection or delibe­ra­te exclusion of a foreign or extrinsic institution from its native context. Our analysis of relevant sources uncovers the evolution of the “lock-in narrative” within institutionalist discourse and its transformation into the concept of “the effect of blockage” in Russian-language literature. To address this translation inaccuracy, which originated in 1997, we propose to reserve the term “blocking” exclusively for instances involving the rejection of a new institution. “Lock-in” is better understood as indicating irreversibility, a strong commitment to, or unwavering adherence to a specific social practice. We explain why it should not be confused with another widely recognized phenomenon in institutional evolution known as “path dependence”. Furthermore, we examine the frequently used Russian-language metaphor “institutional trap”, which is often interchanged with “lock-in”. We highlight that Original Institutional Economics had previously explored these unique cases of institutional evolution long before they were reintroduced into economic theory as part of the lock-in and path dependence narratives. Our paper contributes to the rectification of names (zhèngmíng) aimed at getting rid of redundant substances in academic discourse.
“Conceptual Framework” of Economic Theory: History, Potential, and Prospects of Application
Authors:   Institute of Economics of the Ural Branch of the Russian Academy of Sciences, Dyatel E. P.
Published: September 2023

Conceptual framework stands as a pivotal notion in the methodological landscape of European sciences, having found productive applications in physics, mathematics, linguistics, and sociology. In the realm of economics, however, its potential remains underexplored, making it imperative to explore its heuristic value and integrate this methodological concept in contemporary research. This article aims to outline the conceptual framework of economic theory at different stages of its development and explore how it can organize the structure of economic science. The study analyzes the evolution of conceptualism in a sequence. This journey starts with classical education, shaping a scholar’s worldview, and classical science, combining rational (descriptive) and experimental (explanatory) research. It extends to modern (non-classical) scientific concepts, like neoclassical, evolutionary, and neo-institutional economic theory. The article examines different viewpoints, including those of positivists (E. Mach, R. Carnap, etc.), postpositivists (K. Popper, T. Kuhn, I. Lakatos), and economists (K. Marx, L. Walras, D. North). It identifies and describes the conceptual framework of Marxism, which is based on materialist dialectics and historical materialist perspectives. The article also shows how using the conceptual worldview and fundamental concepts effectively structures normative economics, classical political economy, neoclassicism, and other areas of economics.
Modernizing Investment Technology for Digital Financial Asset Issuance and Trading: An Empirical Study
Authors:   Volgograd Branch of the Plekhanov Russian University of Economics, Goncharova M. V. , Goncharov A. I. ,   Volgograd Branch of the Plekhanov Russian University of Economics,   Volgograd State University
Published: September 2023

The article analyzes Russian investment practices to demonstrate the possibilities for updating the functions of accounting and registration entities (depositories, registrars) and operational-investment firms (ope­rators of financial, investment platforms, information systems for issuing digital financial assets). The focus is made on modernizing technology for digital financial assets, which has stagnated for over two years. The article aims to offer recommendations for improving the issuance and trading of digital financial assets while complying with current Russian financial market regulations. The limitations posed by these regulations have hindered the development of financial support processes for businesses seeking external private investment sources. The research follows a materialistic positivist approach, using diverse scientific methods like statistics, structure analysis, comparisons, and empirical studies. Based on the analysis of operational data from Russian financial companies, the authors propose ways of optimizing their presence in the market. Additionally, the article proposes the establishment of a unified register of investment assets and a depository registration platform under the auspices of the Bank of Russia. It outlines the key components and functional objectives of digi­tal investment and accounting technology within the prudential investment blockchain of the Bank of Russia, which is recommended for use in conjunction with the aforementioned entities. The article proposes establishing an investment marketplace, Investuslugi.ru, within a regulatory sandbox framework and as a subsidiary joint-stock company linked to the Russian Direct Investment Fund, overseen by the Bank of Russia. This marketplace would offer open internet access to issuers and investors and facilitate automatic transactions involving existing and prospective digital investment assets in their best interests.
Content Analysis of the Postgraduate Theses Based on Wood Anatomy in Turkey
Authors: TIRAK HIZAL Kamile
Published: September 2023

This study examines master’s theses and doctoral dissertations on wood anatomy in Turkey in terms of completion year, thesis type, titles of advisors, gender of authors and advisors, universities, subject area, related subjects, samples, stain, and name of wood species. Content analysis was carried out on the theses selected through criterion sampling. The research data were collected through document analysis and analyzed using the SPSS 20.0 program. Within the scope of the research, it was determined that 33 master’s theses and 17 doctoral dissertations, which were found in the thesis scanning center of Higher Education Council (YÖK) of Turkey, were completed in the field of wood anatomy between 1990 and 2022. According to the results, the first thesis indexed by YÖK belongs to 1990 and is master’s thesis, and theses were mainly conducted by female researchers. It was seen that the highest number of postgraduate theses were prepared in Karadeniz Technical University and Istanbul/Istanbul-Cerrahpaşa University. The most studied subject is wood anatomy with fiber morphology, and the most studied other subject is ecological wood anatomy. Both microscopic and macroscopic investigations were done, and most of the theses were only investigated by microscopically. The most used stain was safranin and theses were made on solid wood samples which were cut from the trees or woody plants. This study is very important for scientific developments and will reveal the missing points in the country and provide a vision for future studies.
CURRENT PRINCIPLES OF ANTI-CYTOKINE THERAPY OF SARCOIDOSIS
Authors:   SI “National institute of phthisiology and pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”, Merenkova Ie. O.
Published: September 2023

Sarcoidosis is a systemic granulomatous disease, which may affect any organ, but lungs, lymphatic system and skin either alone or in combination are involved most. Natural course of diseases is quite variable: spontaneous regression may occur, but in approximately 25 % of patients a chronic disease is registered. Based on long term follow-up of 452 sarcoidosis patients, overall mortality was 3,9 and 9 % in 5 and 10 years, respectively. Mortality in sarcoidosis is closely related with progressive pulmonary fibrosis, presence of pulmonary hypertension or concomitant cardio-vascular disease. In 10 % of the patients in average sarcoidosis may become refractory to the standard therapy, which increases the risk of death or disability. Current review uncovers major mechanisms of sarcoidosis, emphasizing the role of several cytokines in development of sarcoid granulomatous inflammation and presents leading principles of anticytokine therapy of sarcoidosis.
Control of PIK3CD by NOD2.
Authors: Mamoor Shahan
Published: September 2023

We provide evidence here from overexpression-based gain-of-function studies in human cells (1, 2) which demonstrate control of the delta catalytic subunit of PI-3-kinase PIK3CD by the NLR (nucleotide-binding oligomerization domain-like receptor) family protein NOD2.
Responsible data sharing: Identifying and remedying possible re-identification of human participants
Authors: Morehouse Kirsten , Kurdi Benedek , Nosek Brian A.
Published: September 2023

Open data collected from humans creates a tension between scholarly values of transparency and sharing on the one hand, and privacy and security on the other. A common solution is to make datasets anonymous by removing personally identifying information before sharing. However, ostensibly anonymized datasets may be at risk of re-identification if they include demographic information. In the present article, we (a) review current privacy standards; (b) describe computer science data protection frameworks and their adaptability to the social sciences; (c) provide practical guidance for assessing and addressing re-identification risk; (d) introduce two open-source algorithms – MinBlur and MinBlurLite – to increase privacy while maintaining the integrity of open data; and (e) highlight aspects of ethical data sharing that require further attention. Technical innovations can support competing values so that science can be as open as possible to promote transparency and sharing, and as closed as necessary to maintain privacy and security.
Reliability of Raman analyses of CO2-dominated fluid inclusions as a rapid barometer at Kīlauea
Authors: DeVitre Charlotte , Wieser Penny
Published: September 2023

Interpreting signals of volcanic unrest requires knowledge of the architecture of the magmatic system, particularly the depths at which magmas are stored. Such information can also be vital to help predict changes in eruptive style and vigour. However, popular petrological tools to assess magma storage depths (e.g., melt inclusions) are costly, present large uncertainties, and are too slow for real-time monitoring. Here, we evaluate the reliability and efficiency of Raman Spectroscopy measurements of CO2-dominated fluid inclusions as a geobarometer relative to more established methods such as microthermometry and melt inclusion barometry. We calculate storage pressures for 102 olivine-hosted fluid inclusions from the 2018 Lower East Rift Zone eruption of Kīlauea, which are statistically indistinguishable to those determined from melt inclusions. We show that calibrated Raman spectroscopy yields densities within 5-10% of microthermometry measurements for CO2-dominated fluid inclusions (< 10% mol H2O in the fluid phase) but is a far more suitable method for systems like Kīlauea dominated by shallow magma storage. Overall, pressures determined from fluid inclusions by Raman spectroscopy are robust, and require only a fraction of the work, time, and resources of melt inclusion studies.
Diurnal cortisol profiles in autistic adolescents and young adults: Associations with social difficulties and internalizing mental health symptoms
Authors: Ilen Laura , Delavari Farnaz , Feller Clémence Mathilde , Zanoletti Olivia , Sandi Carmen , Schneider Maude
Published: September 2023

Several autism-related characteristics, such as social difficulties, may contribute to high perceived stress and increased exposure to stressful life events in some autistic individuals. Repeated exposure to stress might lead to the dysfunction of the hypothalamic-pituitary-adrenocortical (HPA)-axis and be a vulnerability factor for developing mental health difficulties. Previous studies show contradictory findings on salivary cortisol in autism. In the current study, we investigated diurnal cortisol profiles in autistic adolescents and young adults, as well as their associations with social difficulties, stress exposure and mental health symptoms. Autistic (n=48, Mage=17.6) and non-autistic (n=51, Mage=18.4) participants collected salivary cortisol at home six times a day for two days. Social difficulties, exposure to stressful life events/bullying, and mental health symptoms were assessed with questionnaires and clinical interviews. Similar diurnal cortisol slopes (DCS) and cortisol awakening responses (CAR) were observed between the groups, but autistic participants showed higher total cortisol output (AUCG, area under the curve with respect to ground) during the day (b=19.09, p=0.009). In the autistic group, more severe social difficulties were associated with flatter DCS (b=0.01, p=0.007). Finally, cortisol alterations were associated with self-reported mental health symptoms, especially in autistic females in analyses uncorrected for multiple comparisons. In conclusion, our results do not indicate autism-related group-level alterations in most diurnal cortisol measures, but autistic youth showed higher total cortisol (AUCG) compared to non-autistic peers. More detailed investigation of inter-individual variability in cortisol profiles within autistic people might give us important insights into vulnerability to developing stress-related mental health difficulties.
The current practice of latent growth curve modeling in the social and behavioral sciences: Observations and recommendations
Authors: Miller Matt L. , Ferrer Emilio , Ghisletta Paolo
Published: September 2023

We examine recommendations for three key features of latent growth curve models in the structural equation modeling framework. As a basis for the discussion, we review current practice in the social and behavioral sciences literature as found in 441 reports published in the 19 months beginning in January 2019 and compare our findings to extant recommendations. We then provide suggestions for empirical researchers, reviewing the application of these very popular models, specifically focusing on comparison of alternative change models, time metric and interval features implemented, and the treatment of individually-varying time intervals.
Burst versus continuous delivery design in digital mental health interventions: evidence from a randomized clinical trial.
Authors: Marciniak Marta Anna , Shanahan Lilly , Yuen Kenneth S.L. , Veer Ilya , Walter Henrik , Tüscher Oliver , Kobylinska Dorota , Kalisch Raffael , Hermans Erno , Binder Harald , Kleim Birgit
Published: September 2023

Objective: Digital mental health interventions delivered via smartphone-based apps effectively treat various conditions, but optimizing their efficacy while minimizing participant burden remains a key challenge. Here, we investigated the potential benefits of a burst delivery design, i.e., intervention delivered only in pre-defined time intervals, in comparison to the continuous delivery of the intervention.Methods: We randomly assigned ninety-three participants to continuous delivery (CD) or burst delivery (BD) groups. The CD engaged in ReApp, a mobile app that increases positive cognitive reappraisal with a consistent delivery schedule with five prompts per day throughout the three-week-long study, while BD received five daily prompts only in the first and third weeks of the study.Results: No significant differences were found between the groups in adherence, mental health outcomes, specifically depressive and anxiety symptoms, and the level of perceived stress, and perceived helpfulness of the intervention. BD group significantly decreased in perceived difficulty of the intervention over time.Conclusions: These results suggest that the burst delivery may be as suitable for digital mental health interventions as the continuous delivery. The perceived difficulty of the intervention declined more steeply for the BD group, indicating that it has improved the feasibility of the positive cognitive reappraisal intervention, without hurting its efficacy. This outcome may inform the design of less burdensome interventions with improved outcomes in future research.
Comparing summed probability distributions of shoreline and radiocarbon dates from the Mesolithic Skagerrak coast of Norway
Authors: Roalkvam Isak , Solheim Steinar
Published: September 2023

By developing a new methodology for handling and assessing a large number of shoreline dated sites, this paper compares the summed probability distribution of radiocarbon dates and shoreline dates along the Skagerrak coast of south-eastern Norway. Both measures have previously been compared to elucidate demographic developments in Fennoscandia, but these have not been based on probabilistic methods for shoreline dating. The findings indicate a largely diverging development of the two data sets through the Mesolithic. The number of shoreline dated sites undergoes some process of overall decrease through the period, while the radiocarbon data is characterised by a lacking signal in the earliest parts of the period and then undergoes a logistic growth that quickly plateaus and remains stable for the remainder of the period. The precise nature of this discrepancy will necessitate further substantiation and the method of shoreline dating itself still requires further testing and assessment. Having noted this, we still tentatively suggest that while the number of shoreline dated sites is not devoid of influence from a demographic signal, this measure could be more heavily influenced by mobility patterns. Conversely, we also suggest that the lacking radiocarbon data from the earliest part of the Mesolithic is in part the result of mobility patterns, but that the radiocarbon data more directly reflects population dynamics.
The Micro Socio-Economic Class scheme
Authors: Smallenbroek Oscar , Hertel Florian R. , Barone Carlo
Published: September 2023

This document describes the development of the Micro Socio-Economic Class Scheme (MSECS), which was assessed against other class schemes by Hertel, Barone, Smallenbroek (2023). MSECS goal is to develop a micro-level disaggregation of the European Socio-economic Classification (ESEC) (Rose, Harrison 2010) and of its variant ESEC-MP, which disaggregates managers and professional (Smallenbroek, Hertel, Barone 2022). MSECS is an adaptation of ESEG (Meron et al. 2014) that can be nested into ESEC thus providing a micro-level scheme with 37 categories within macro-level ESEC categories. This nested scheme arguably inherits the theoretical rationale from ESEC to the extent that MSECS categories while respecting the boundaries drawn by employment relations.
Orthodontic pain – the state of the evidence
Authors: Cheong Joo Ming , Tolos Siti Marponga
Published: September 2023

Pain is a common side effect of orthodontic treatment. An understanding of its mechanism, implications and subsequent management is essential for any orthodontist to improve patient compliance and satisfaction with treatment. This paper provides a comprehensive review and state of the evidence on orthodontic pain from the viewpoint of clinicians and patients – clinical features, its pathways, factors influencing pain perception, and finally the pharmacological and non-pharmacological management of orthodontic pain.
Prevalence and orthodontic management of missing permanent maxillary lateral incisor at a referral centre in Sabah
Authors: Lee Jin Han
Published: September 2023

This was a cross-sectional study of the prevalence and orthodontic management of developmental missing permanent maxillary lateral incisor of patients referred for orthodontic treatment from year 2010 to 2020. The dental records of written case notes, radiographs, and study models that fulfilled the inclusion criteria were selected using systematic sampling and were assessed retrospectively. Sample were taken from every five dental records. Dental records that did not fulfil the inclusion criteria were substituted. Data taken were the demographic data, side of the missing maxillary lateral incisor, and the orthodontic management. All variables were analysed descriptively. The differences between orthodontic open space and orthodontic close space with respect of unilateral and bilateral missing permanent maxillary lateral incisor were tested using Fisher’s exact test. From the total of 291 samples, there were 11 (3.78%) patients presented with missing permanent maxillary lateral incisor. The mean age of the patients was 17.46 ± 1.52 years. All 11 patients were females. There were six (54.55%) patients presented with bilateral missing permanent maxillary lateral incisor, while five (45.45%) were unilateral. From the unilateral group, there were three (27.27%) patients presented with right side missing permanent maxillary lateral incisor. Six (54.55%) patients were treated with orthodontic open space, while five (45.45%) patients were treated with orthodontic close space. In conclusion, the prevalence of missing permanent maxillary lateral incisor was 3.78%. All patients were females. More patients presented with bilateral missing permanent maxillary lateral incisor. The treatments provided were orthodontic open space and orthodontic close space.
An All-Inclusive Digital Framework for Collaborative Community Transformation for Sustainable Development
Authors: Olowolayemo Akeem , Daud Nuha Hafizah , Tanni Maymuan Gulfam , Omar Ba Khadher Mohammed Abdullah
Published: September 2023

Technology as a part of world development can be utilized for public welfare and services. In this current era, people's lives and activities depend mostly on technology. Consequently, technology can foster massive contribution to problem-solving in communities and can easily enable several services hitherto considered difficult. One area of interest is the utilization of technology to enable faster solutions to common problems in a community. Monitoring the challenges and developments in a community through a community reporting and collaborative transformation system is still not that popular despite the obvious benefits. The idea of crafting a digital collaborative transformation system becomes crucial to solving the common problems in a community and how to achieve a smooth collaborative relationship between the citizens and their respective political representatives. Consequently, this study aims to offer a comprehensive framework for the development of a digital collaborative community transformation, consisting of community members’ responses and communication channels linked with the person-in-charge,  budgeting suggestions, volunteering, as well as nomination and voting systems. The approach adopted in this study is to use an exploratory strategy to discuss all the critical processes from the standpoint of the users, as well as the technology for designing, creating, and integrating the system to gather users’ inputs.
Application of Data Science on Food Waste Problem: A Preliminary Work
Authors: Ramlan Amir Syazwan , Mohamad Dzain Iman Zulhakim , Hassan Raini
Published: September 2023

Food waste refers to food that is fit for human consumption, but is discarded after it is kept past its expiration date or allowed to spoil due to factors like food spoilage, market surplus, and individual shopping and eating habits. It is a common problem worldwide, including in Malaysia. In reality, one-third of the total food generated is wasted or lost annually, and at least 820 million people worldwide do not have sufficient food. This study attempts to observe the current trends in the amount of food waste generated in Malaysia so that the public awareness can be increased. This paper also wishes to study about the undernourishment crisis for lowering the extreme hunger issues and to reduce the food losses especially rice, along the production and supply chain. This study indirectly aligns with sustainable development goals (SDG) related to zero hunger, and responsible consumption and production. Initially, the data science processes were implemented including data collection, data pre-processing, data cleaning, data exploration and selection, data wrangling, and exploratory data analysis (EDA). In Japan, the food waste issue was not given enough attention. It reflects the significant upswing in its early graph, which then began to decline. On the other hand, the food waste issue in Korea initially exhibited a sharp surge before a progressive drop. Regarding the undernourishment issue, almost all Southeast Asian nations nowadays are putting a lot of effort into eradicating or drastically lowering undernutrition among their citizens compared to the past. Rice is the common food type in Southeast Asia, which means it gets discarded frequently. The residents of Southeast Asia regard rice as a main food source.