bluuebunny/crossref_metadata_2025 huggingface dataset:
Immersive virtual reality fitness games for enhancement of recovery after colorectal surgery: study protocol for a randomised pilot trial
Authors: Wolf Sebastian , Zanker Johannes , Sommer Florian , Vlasenko Dmytro , Pinto David R. M. , Hoffmann Michael , Anthuber Matthias , Schrempf Matthias C.
Published: December 2022

Background

Physical inactivity after surgery is an important risk factor for postoperative complications. Compared to conventional physiotherapy, activity-promoting video games are often more motivating and engaging for patients with physical impairments. This effect could be enhanced by immersive virtual reality (VR) applications that visually, aurally and haptically simulate a virtual environment and provide a more interactive experience. The use of VR-based fitness games in the early postoperative phase could contribute to improved mobilisation and have beneficial psychological effects. Currently, there is no data on the use of VR-based fitness games in the early postoperative period after colorectal surgery.

Methods

This pilot trial features a single-centre, randomised, two-arm study design with a 1:1 allocation. Patients undergoing elective abdominal surgery for colorectal cancer or liver metastases of colorectal cancer will be recruited. Participants will be randomly assigned to an intervention group or a control group. Patients randomised to the intervention group will perform immersive virtual reality-based fitness exercises during their postoperative hospital stay. Feasibility and clinical outcomes will be assessed.

Discussion

Early mobilisation after surgery is crucial for reducing many postoperative complications. VR-based interventions are easy to use and often inexpensive, especially compared to interventions that require more medical staff and equipment. VR-based interventions could serve as an alternative or complement to regular physiotherapy and enhance mobilisation after surgery. The proposed pilot study will be the first step to evaluate the feasibility of VR-based interventions in the perioperative period, with the aim of improving the postoperative rehabilitation of cancer patients.

Trial registration

The trial has been registered in the German Clinical Trials Register (DRKS) Nr. DRKS00024888, on April 13, 2021, WHO Universal Trial Number (UTN) U1111-1261–5968.
Biomimetic hydrogel blanket for conserving and recovering intrinsic cell properties
Authors: Um Seung-Hoon , Seo Youngmin , Seo Hyunseon , Lee Kyungwoo , Park Sun Hwa , Jeon Jung Ho , Lim Jung Yeon , Ok Myoung-Ryul , Kim Yu-Chan , Kim Hyunjung , Cheon Cheol-Hong , Han Hyung-Seop , Edwards James R. , Kim Sung Won , Jeon Hojeong
Published: December 2022

Background

Cells in the human body experience different growth environments and conditions, such as compressive pressure and oxygen concentrations, depending on the type and location of the tissue. Thus, a culture device that emulates the environment inside the body is required to study cells outside the body.

Methods

A blanket-type cell culture device (Direct Contact Pressing: DCP) was fabricated with an alginate-based hydrogel. Changes in cell morphology due to DCP pressure were observed using a phase contrast microscope. The changes in the oxygen permeability and pressure according to the hydrogel concentration of DCP were analyzed. To compare the effects of DCP with normal or artificial hypoxic cultures, cells were divided based on the culture technique: normal culture, DCP culture device, and artificial hypoxic environment. Changes in phenotype, genes, and glycosaminoglycan amounts according to each environment were evaluated. Based on this, the mechanism of each culture environment on the intrinsic properties of conserving chondrocytes was suggested.

Results

Chondrocytes live under pressure from the surrounding collagen tissue and experience a hypoxic environment because collagen inhibits oxygen permeability. By culturing the chondrocytes in a DCP environment, the capability of DCP to produce a low-oxygen and physical pressure environment was verified. When human primary chondrocytes, which require pressure and a low-oxygen environment during culture to maintain their innate properties, were cultured using the hydrogel blanket, the original shapes and properties of the chondrocytes were maintained. The intrinsic properties could be recovered even in aged cells that had lost their original cell properties.

Conclusions

A DCP culture method using a biomimetic hydrogel blanket provides cells with an adjustable physical pressure and a low-oxygen environment. Through this technique, we could maintain the original cellular phenotypes and intrinsic properties of human primary chondrocytes. The results of this study can be applied to other cells that require special pressure and oxygen concentration control to maintain their intrinsic properties. Additionally, this technique has the potential to be applied to the re-differentiation of cells that have lost their original properties.
A demand side controller of electrolytic aluminum industrial microgrids considering wind power fluctuations
Authors: Ding Xin , Xu Jian , Sun Yuanzhang , Liao Siyang , Zheng Jingwen
Published: December 2022

Direct wind power purchase for large industrial users is a meaningful way to improve wind power consumption and decrease industrial production costs. Short-term wind power fluctuations may lead to large-scale wind power curtailment problems. To promote use of wind energy, a demand side control method is proposed based on output regulator theory for a grid-connected industrial microgrid with electrolytic aluminum loads to continuously track and respond to wind power fluctuations. The control model of the EALs and the dominant frequencies of the wind power fluctuation signals are analyzed and incorporated into the demand side control plant. The feedback control signals with active power deviations on the tie-line are used to design the demand side controller. Simulations are conducted for an actual industrial microgrid to validate the feasibility and effectiveness of the proposed method. The results demonstrate that the proposed controller based on output regulator theory is able to effectively track wind power fluctuations.
Lymphopenia during 177Lu-DOTATATE therapy leading to recurrence of tuberculosis: a case report
Authors: Boughdad Sarah , Da Mota Michael , Mendes De Carvalho Mélanie , Firsova Maria , Prior John O. , Schaefer Niklaus
Published: December 2022

We report the case of a 72-year-old woman who presented with tuberculous arthritis during the setting of 177Lu-DOTATATE therapy for a grade-2 neuro-endocrine pancreatic tumor with liver metastases. We hypothesized that this recurrence might have been related to the occurrence of lymphopenia, which is common during PRRT. Indeed, though lymphopenia is frequently dismissed, it could lead to the development of opportunistic diseases and its severity should be examined, especially in case of abnormal clinical symptoms.
Long loop technique with bifemoral access as salvage technique for repositioning of dislodged port catheters
Authors: Van den Bosch Vincent , De Beukelaer Frédéric , Isfort Peter , Keil Sebastian , Kuhl Christiane K. , Bruners Philipp , Pedersoli Federico
Published: December 2022

Background

Repositioning of dislocated port systems’ catheters is usually performed with a pigtail catheter and/or a goose snare. In case of an inaccessible port catheter tip due to thrombosis, this classic approach may be not successful. For these cases, we describe a long loop bailout technique with bifemoral access.

Technique

Via a right transfemoral access, a first attempt to reposition the dislodged port catheter using pigtail catheter and goose snare was performed. After an unsuccessful attempt and delineation of thrombosis of the catheter tip, the contralateral femoral vein was subsequently punctured and a sheath was placed. Through both vascular sheaths, pigtail catheter and goose wire were advanced distally to the catheter. The guidewire in the pigtail catheter was snared, thus creating a “Long loop” configuration. Pulling down both catheters simultaneously with improved stability allowed to detach the catheter tip from the vessel wall and replacement into the superior vena cava was possible. Refinement of catheter tip position was done using the goose snare. This technique was applied on 5 patients with dislodged port catheters in the jugular vein (2/5), the innominate vein (1/5), the subclavian vein (1/5) and the azygos vein (1/5) with a technical success of 100%. No complications were observed.

Conclusion

The Long loop technique can be used as salvage approach to reposition a dislodged catheter in case of failure with pigtail catheter and goose snare.
The Stieda process of the talus: the anatomical knowledge and clinical significance of an overlooked protrusion
Authors: Ogut Eren
Published: December 2022

Background

The Stieda process (SP) is an extended lateral tubercle of the posterior process of the talus. Although there are different classifications for SP in the literature, it is essential to know the differential diagnosis of SP from fractures and accessory ossicles. This review aims to classify the SP and to guide the formation, prevalence, etiopathology, symptoms, differential diagnosis, and treatment.

Main body of the abstract

The authors conducted a literature review that lasted up to September 2022 and used the databases PubMed, Web of Science, and Google Scholar to explore the SP of the talus in all of its aspects. Out of 3802 publications, only 34 could be included, and most of them were studies on posterior ankle impingement syndrome (PAIS). The occurrence, prevalence, etiopathology, clinical significance, symptoms, differential diagnosis, and treatment methods of SP were investigated based on the literature. SP is formed by the fusion of a secondary ossification center at the posterolateral side of the talus with an incidence of 12–36.5%. It is frequently observed in males. It causes reduced plantar flexion, impairment in the inversion of the foot, pain, and swelling in the posterior ankle joint, PAIS, and SP fractures after trauma.

Short conclusion

SP can be diagnosed by lateral ankle radiography or MRI in patients complaining of PAIS. The initial treatment of the SP should include reducing inflammation, swelling, pain, and limiting activities. If neither modality affects the patient, surgical treatment will be performed, and SP will be resected until the impingement disappears.
Gut microbiota of homing pigeons shows summer–winter variation under constant diet indicating a substantial effect of temperature
Authors: Dietz Maurine W. , Matson Kevin D. , Versteegh Maaike A. , van der Velde Marco , Parmentier Henk K. , Arts Joop. A. J. , Salles Joana F. , Tieleman B. Irene
Published: December 2022

Background

Gut microbiotas play a pivotal role in host physiology and behaviour, and may affect host life-history traits such as seasonal variation in host phenotypic state. Generally, seasonal gut microbiota variation is attributed to seasonal diet variation. However, seasonal temperature and day length variation may also drive gut microbiota variation. We investigated summer–winter differences in the gut bacterial community (GBC) in 14 homing pigeons living outdoors under a constant diet by collecting cloacal swabs in both seasons during two years. Because temperature effects may be mediated by host metabolism, we determined basal metabolic rate (BMR) and body mass. Immune competence is influenced by day length and has a close relationship with the GBC, and it may thus be a link between day length and gut microbiota. Therefore, we measured seven innate immune indices. We expected the GBC to show summer–winter differences and to correlate with metabolism and immune indices.

Results

BMR, body mass, and two immune indices varied seasonally, other host factors did not. The GBC showed differences between seasons and sexes, and correlated with metabolism and immune indices. The most abundant genus (Lachnoclostridium 12, 12%) and associated higher taxa, were more abundant in winter, though not significantly at the phylum level, Firmicutes. Bacteroidetes were more abundant in summer. The Firmicutes:Bacteroidetes ratio tended to be higher in winter. The KEGG ortholog functions for fatty acid biosynthesis and linoleic acid metabolism (PICRUSt2) had increased abundances in winter.

Conclusions

The GBC of homing pigeons varied seasonally, even under a constant diet. The correlations between immune indices and the GBC did not involve consistently specific immune indices and included only one of the two immune indices that showed seasonal differences, suggesting that immune competence may be an unlikely link between day length and the GBC. The correlations between the GBC and metabolism indices, the higher Firmicutes:Bacteroidetes ratio in winter, and the resemblance of the summer–winter differences in the GBC with the general temperature effects on the GBC in the literature, suggest that temperature partly drove the summer–winter differences in the GBC in homing pigeons.
Developing a co-production strategy to facilitate the adoption and implementation of evidence-based colorectal cancer screening interventions for rural health systems: a pilot study
Authors: Kim Jungyoon , Estabrooks Paul , Aggarwal Alisha , McMillan Analisa , Alshehri Khalid
Published: December 2022

Background

Evidence-based colorectal cancer screening (CRCS) interventions have not been broadly adopted in rural primary care settings. Co-production of implementation strategies through a bundled approach may be promising in closing this gap by helping rural healthcare practitioners select and implement the best fitting CRCS interventions to the local context. This paper describes the process and outcomes of co-development and delivery of the bundled implementation strategy to improve adoption and implementation of CRCS interventions with two rural clinics.

Methods

We used a bundle of implementation strategies with a core focus on academic-clinical partnership development (strategy 1) and Plan-Do-Study-Act cycles (strategy 2) to identify clinical partner interests/preferences on delivery methods and content needed to facilitate intervention identification and implementation that improves CRCS. We also developed an implementation blueprint for each clinic (strategy 3) through an online blueprinting process based on adapted “Putting Public Health Evidence in Action” (PPHEA) training curriculum. Clinic physicians and staff (n = 7) were asked to evaluate the bundled approach based on overall reactions and perceptions of innovation characteristics using 5-point Likert scale. After completing the bundled approach, we collected implementation outcomes and limited intervention effectiveness of the CRCS evidence-based interventions (EBIs) developed through the process.

Results

Our co-production strategy yielded a prototype online blueprinting process consisting of 8 distance-learning PPHEA modules that guide selection and implementation of EBIs tailored to CRCS. Modules were delivered to clinic participants with minor adaptations, using PDSA cycle to improve quality of module contents and formats. Overall, participants in both clinics reported positive reactions toward the bundled approach. Both clinics reported improvements in how they perceived the characteristics of the innovation (the bundled approach) to tailor selected CRCS EBIs. As a result of the bundled strategies, each clinic selected and adopted specific EBI(s) with the varying degrees of implementation and CRCS outcomes.

Conclusions

The bundle of implementation strategies used were feasible and acceptable in rural primary care practices to facilitate the use of EBIs to improve CRCS.
Analysis of variance of injection moulding process parameters and clay particles size effects on impact strength, shrinkage and warpage of polyethylene/kaolin clay composites
Authors: Trish Abdulrouf , Elhrari Wael , Etmimi Hussein , Klash Abdalah
Published: December 2022

A correlation effect between particle size of kaolin clay and injection moulding process parameters on impact strength, shrinkage and warpage of high-density polyethylene/kaolin clay (HDPE/KC) composites was carried out using analysis of variance (ANOVA). Kaolin clay with particle sizes of < 75, 75–106 and 106–150 μm was used. The process parameters that were taken into consideration were injection temperature, packing pressure and packing time. In general, experimental results showed that the impact strength and shrinkage of the HDPE/KC composites clearly depended on the injection temperature. However, no clear dependency of the warpage on the injection temperature was observed. Furthermore, clay particle size showed to have an influence only on the shrinkage of the composites, where smaller clay particle size led to injected composite parts with relatively less shrinkage. ANOVA showed that the effect of injection temperature on shrinkage of composites containing clay particle sizes of < 75 and 106–150 μm was statistically significant (p= 0.01 and 0.04, respectively). However, the effect of injection temperature on shrinkage of the composite made with clay having particle sizes of 75–106 μm was not significant (p= 0.07). ANOVA also indicated that the injection temperature effect on the impact strength of composites that contain clays with particle sizes of < 75 μm and 75–106 μm was significant (p= 0.03 andp= 0.01, respectively), whereas the injection temperature effect on the impact strength of the composite containing clay with a particle size of 106–150 μm was not significant (p= 0.17). Contrary to shrinkage and impact strength, the effect of the studied parameters on the warpage was not statistically significant, which was in good agreement with the experimental observations.
Modelling mood updating: a proof of principle study
Authors: Clark James E. , Watson Stuart
Published: December 2022

Background

Recent developments in computational psychiatry have led to the hypothesis that mood represents an expectation (prior belief) on the likely interoceptive consequences of action (i.e. emotion). This stems from ideas about how the brain navigates its external world by minimising an upper bound on surprisal (free energy) of sensory information and echoes developments in other perceptual domains.

Aims

In this paper we aim to present a simple partial observable Markov decision process that models mood updating in response to stressful or non-stressful environmental fluctuations while seeking to minimise surprisal in relation to prior beliefs about the likely interoceptive signals experienced with specific actions (attenuating or amplifying stress and pleasure signals).

Method

We examine how, by altering these prior beliefs we can model mood updating in depression, mania and anxiety.

Results

We discuss how these models provide a computational account of mood and its related psychopathology and relate it to previous research in reward processing.

Conclusions

Models such as this can provide hypotheses for experimental work and also open up the potential modelling of predicted disease trajectories in individual patients.
Construção de agenda e desafios locais à valorização e ao desenvolvimento coletivo do negócio de artesanato no Alto do Moura-PE
Authors: Sousa Jessica Rani Ferreira de , Sá Marcio , Lorêto Myrna Suely Silva , Souza Denise Clementino de
Published: December 2022

Este trabalho teve como objetivo analisar os principais desafios à formação de uma agenda pública para valorização e desenvolvimento coletivo do artesanato no Alto do Moura, centro de artes figurativas em barro situado no município de Caruaru, Pernambuco. Por meio de pesquisa qualitativa, foram efetuadas entrevistas com artesãos e formadores de opinião, com grupos focais e elaboração de notas de campo. A técnica utilizada foi a análise temática de conteúdo do material empírico. Os principais desafios elencados corresponderam à complexidade e à multidimensionalidade das demandas relatadas; à necessidade de sensibilidade no olhar para as questões simbólicas referentes a traços culturais da atividade artesã; à dissonância entre a visão do negócio pelos artesãos e visão adotada pelo poder público e órgãos de fomento e, por fim, à gestão da transversalidade de questões que demandam políticas intersetoriais.
Instabilidade das burocracias decisórias, planejamento e ineficiência no ciclo das políticas públicas
Authors: Lopez Felix
Published: December 2022

Neste artigo tecnológico, argumenta-se que um dos principais problemas no planejamento e naimplementação de políticas públicas no Brasil é a instabilidade dos membros das burocracias decisóriasem seus cargos, na União, nos estados e nos municípios. O artigo apresenta as evidências para fundamentar o argumento com base na análise de dados sobre a rotatividade e o tempo de duração dos dirigentes nos cargos. Discute, em seguida, os principais incentivos a esse fenômeno, de maneira especial a fragmentação partidária e os incentivos das regras eleitorais. O texto apresenta as implicações do fenômeno para o campo das políticas públicas, entre as quais as dificuldades de construir capacidades de planejamento de médio e longo prazo e, de modo indireto, o desperdício de recursos públicos. Sugere-se, ao final, que um dos meios de mitigar o problema, para além de alterar incentivos partidários e eleitorais, é estreitar os níveis de discricionariedade na escolha dos dirigentes em níveis inferiores ao topo da hierarquia decisória.
Case Report: Ludwig's angina - 'The Dangerous Space'
Authors: Vasanth Satish , Chandran Satheesh , Pandyan Deepak Abraham , Gnanam Padmashini , Djearamane Sinouvassane , Wong Ling Shing , Selvaraj Siddharthan
Published: December 2022

Background: Ludwig's angina is a potentially life-threatening disease characterized by diffuse bilateral cellulitis with an odontogenic origin. This unique infection is now rare owing to the antibiotic era.

Case: This patient presented to the emergency room with trismus, jaw and neck swelling, mild respiratory distress with tachypnea, hyperthermia, and panic. Clinical examination and radiographic evaluation confirmed the diagnosis of Ludwig's angina. As it is a quickly spreading infection, the patient was taken up for immediate surgical decompression leading to pus drainage, removal of the offending tooth, bacterial culture and sensitivity, and administration of empirical antibiotics. As we had operated promptly, there was no need for emergency airway intervention, and the patient had immediate relief from airway distress.

Conclusions: Early accurate diagnosis with conservative surgical decompression, thereby negating the need for airway intervention, was vital to avoiding mortality which is always possible in such an expeditious infection.
Small groups satisfy: A descriptive analysis of engagement in virtual learning
Authors: Sallander Kayla , Yarnell Angela , Barry Erin
Published: December 2022

Background: Due to COVID-19 restrictions, students participated in a virtual Summer Leadership Program (SLP), consisting of small group discussions and large lectures, instead of a more traditional in-person experience. The purpose of this paper was to assess what forms of virtual learning students found most engaging during their summer leadership training.

Methods: Students were surveyed prior to and after the SLP. The pre-survey included seven Likert-scale questions and one free response question (Google form survey open from 7/14/20-7/16/20). The post-survey included 24 Likert-scale questions and four open-answer questions (Google form survey open from 7/23/20-7/24/20). Both surveys were administered to all first year students at Uniformed Services University (N=176). There were 158 responses for the pre-SLP survey and 123 responses for the post-SLP survey. Topics focused on expectations, engagement, self-assessment, and areas for improvement.

Results: Survey results showed that students were most engaged with small group sessions where they were asked to apply their knowledge and skills. Students felt less engaged in large lectures.

Conclusion: In the virtual environment, students are more engaged in small group settings where they are asked to apply their knowledge and skills. This information can be used to plan sessions within the virtual environment to garner increased engagement from students.
Preferences and expectations of feedback of individual genetic research results in African genomics: Views of South African parents of children with neurodevelopmental disorders
Authors: Matshabane Olivia P , Albertus Cleo A , Faure Marlyn C , Ralefala Dimpho , Donald Kirsten A , Wonkam Ambroise , De Vries Jantina
Published: December 2022

Background: Genomic research is expanding at an exponential pace across the globe and increased access to genome analysis has led to greater generations of genetic results with specific relevance to individuals. This study aims to explore preferences and expectations of feedback of individually relevant genetic research results among parents of children with neurodevelopmental conditions.

Methods: Following a qualitative approach, we conducted four deliberative focus group discussions with (n=27) South African parents of children involved in genomics research on neurodevelopmental disorders.

Results: Most participants expressed a strong interest in receiving genetic results regardless of severity, actionability and preventability.  These results were viewed as valuable because they could empower or emancipate individuals, families, and communities. Receiving risk information was also believed to motivate healthier lifestyle choices. However, some participants were uncertain or articulated a desire not to receive results due to fears of anxiety or psychological distress. In addition, participants expected to receive results as a demonstration of respect from researchers and articulated it as an act to build trust between researchers and participants.

Conclusions: Internationally, a debate continues around whether individually relevant genetic results should or should not be fed back to participants of genomic research studies. In Africa, there is scant literature which has investigated this question and no policies to guide researchers. This study provides a basis of empirical data on perspectives of African participants which could inform work on the development of a consolidated approach to the feedback of genetic research results in the continent.
Protocol for the Addressing the Social Determinants and Consequences of Tuberculosis in Nepal (ASCOT) pilot trial
Authors: Rai Bhola , Dixit Kritika , Dhital Raghu , Rishal Poonam , Gurung Suman Chandra , Paudel Puskar Raj , Mishra Gokul , Bonnett Laura , Siqueira-Filha Noemia , Khanal Mukti Nath , Lonnroth Knut , Squire S Bertel , Caws Maxine , Wingfield Tom
Published: December 2022

BACKGROUND: The World Health Organization’s End TB (tuberculosis) Strategy advocates social and economic support for TB-affected households but evidence from low-income settings is scarce. We will evaluate the feasibility and acceptability of a locally-appropriate socioeconomic support intervention for TB-affected households in Nepal.

METHODS: We will conduct a pilot randomised-controlled trial with mixed-methods process evaluation in four TB-endemic, impoverished districts of Nepal: Pyuthan, Chitwan, Mahottari, and Morang. We will recruit 128 people with TB notified to the Nepal National TB Program (NTP) and 40 multisectoral stakeholders including NTP staff, civil-society members, policy-makers, and ASCOT (Addressing the Social Determinants and Consequences of Tuberculosis) team members. People with TB will be randomised 1:1:1:1 to four study arms (n=32 each): control; social support; economic support; and combined social and economic (socioeconomic) support. Social support will be TB education and peer-led mutual-support TB Clubs providing TB education and stigma-reduction counselling. Economic support will be monthly unconditional cash transfers during TB treatment with expectations (not conditions) of meeting NTP goals. At 0, 2, and 6 months following TB treatment initiation, participants will be asked to complete a survey detailing the social determinants and consequences of TB and their feedback on ASCOT. Complementary process evaluation will use focus group discussions (FGD), key informant interviews (KII), and a workshop with multi-sectoral stakeholders to consider the challenges to ASCOT’s implementation and scale-up. A sample of ~100 people with TB is recommended to estimate TB-related costs. Information power is estimated to be reached with approximately 25 FGD and 15 KII participants.

CONCLUSIONS: The ASCOT pilot trial will both generate robust evidence on a locally-appropriate, socioeconomic support intervention for TB-affected households in Nepal and inform a large-scale future ASCOT trial, which will evaluate the intervention’s impact on catastrophic costs mitigation and TB outcomes.

The trial is registered with the ISRCTN (ISRCTN17025974).
Modeling of processes in semiconductor structures under radiation exposure
Authors: Zolnikov Konstantin , Gamzatov N. , Evdokimova Svetlana , Potapov Andrey , Dopira Roman , Kucherov Yuriy , Yanochkin Igor' , Stoyanov Sergey Vital'evich , Plotnikov Aleksey
Published: December 2022

The radiation impact of outer space has an impact on electronic equipment and their characteristics change. The paper considers the simulation of the process of motion of holes generated in the oxide, which cause local deformation of the potential field of the lattice. Jumps of polarons make the motion of holes dispersed and highly dependent on temperature and oxide thickness. The article presents the temperature dependences of the voltage shift after a single radiation pulse. When holes move to the Si/SiO2 interface, some of the holes are captured by traps. The effect of the influence of the capture cross section on the increase in holes in traps is noticeable in the electrical dependence of the increase in the number of oxide traps immediately after irradiation. The graphs of the dependence of the threshold voltage shift due to oxide traps on the electric field in the oxide are plotted in this work. Immediately after its appearance, the charge of oxide traps begins to be neutralized. To study this process, time, temperature, and electrical dependences are plotted, and the ratio of trapped electrons to the number of trapped holes is shown for dry and wet gate oxide technologies at different oxide thicknesses. Thus, the influence of temperature and radiation influences on the motions of holes and oxide traps in semiconductor structures is shown.
On some models of optimization of crop production under conditions of biological risks
Authors: Barsukova Margarita , Ivano Yaroslav , Kolokol'ceva Irina
Published: December 2022

The aim of the work is to build and use problems of parametric and stochastic programming to solve problems of optimizing the production of agricultural products under conditions of biological risks. To achieve the goal, two tasks were solved: determining the patterns of variability of some series characterizing possible risks in crop production, and building mathematical models to optimize crop production, taking into account the damage caused by plant pests. The paper proposes models for optimizing the production of crop products under conditions of biological risks. Some indicators of such tasks are described using probabilistic estimates. To optimize the production of agricultural products under the influence of biological risks, mathematical models with probabilistic estimates, as well as a parametric programming model, were built. Examples of approbation of models in the planning of production of crop production are given. The work used materials on the number of rodents, invasions of locust pests for the long-term period 2009-2020. according to the Irkutsk region. In addition, information on the yield of agricultural crops in the municipalities of the southern territory of the region, as well as data on the activities of CJSC Irkutsk Semen, located in the Irkutsk region, are involved. To model series on the number of rodents, areas of distribution of acridoids and the number of their larvae per unit area, methods of probability theory and mathematical statistics were used (technologies for constructing probability distribution laws, regression analysis and assessment of the quality of models). The variability of agricultural crop yields was assessed using the methods of constructing trends and factor dependencies. When optimizing the production of crop products, methods for constructing and solving extreme problems were used. Models of parametric and stochastic programming are proposed. At the same time, the experience of developing applied models for optimizing the production of agricultural products with and without taking into account risks was applied.
Development of a quantitative investment algorithm based on Random Forest
Authors: Novikova Tatyana , Evdokimova Svetlana , Wu Gotsui
Published: December 2022

In modern research of the stock market, specialists and scientists are improving algorithms and models, combining them with each other, with strategies and market conditions for stock selection. This paper presents an overview of stock selection models for quantitative investment, which was the basis for the proposed procedure and algorithm of quantitative investment, which allow modeling the investment process. The developed algorithm is based on the CART decision tree and Random Forest, which includes the bagging algorithm. The bagging algorithm divides the training set into several new training sets that build their own calculation models, and then their results are summed and integrated to obtain the final prediction. The randomness of Random Forest comes into play in the process of selecting samples from the training dataset and in selecting features to calculate the best split points. However, the proposed strategy is more stable than other stock selection strategies, is more suitable for building quantitative stock selection models, the proposed algorithm has an advantage over other algorithms, and is also more promising for further development.
Affine-periodic solutions for generalized ODEs and other equations
Authors: Federson Márcia , Grau Rogelio , Mesquita Carolina
Published: December 2022

It is known that the concept of affine-periodicity encompasses classic notions
of symmetries as the classic periodicity, anti-periodicity and rotating symmetries
(in particular, quasi-periodicity). The aim of this paper is to establish the basis
of affine-periodic solutions of generalized ODEs. Thus, for a given real number $T> 0$ and an invertible $n\times n$ matrix $Q$, with entries in $\mathbb C$,
we establish conditions for the existence of a $(Q,T)$-affine-periodic solution
within the framework of nonautonomous generalized ODEs, whose integral form displays the nonabsolute Kurzweil integral, which encompasses many types
of integrals, such as the Riemann, the Lebesgue integral, among others. The main tools employed here are the fixed point theorems of Banach and of Krasnosel'skiĭ.
We apply our main results to measure differential equations with
Henstock-Kurzweil-Stiejtes righthand sides as well as to impulsive differential equations and dynamic equations on time scales which are particular cases of the former.
Cor Triatriatum and Recurrent Thromboembolic Stroke
Authors: Zaw Hein Htet
Published: December 2022

A woman with recurrent thromboembolic stroke was found to also have cor triatriatum. When the patient first presented with weakness, she was thought to have ischaemic stroke because she had conventional risk factors, but she was later confirmed to have cor triatriatum. The main method of treatment is surgery. However, if surgery is contraindicated, anticoagulation can be used as second-line treatment, but this can be difficult. This report describes the follow-up of a middle-aged female patient with cor triatriatum over 6 years during which she experienced multiple strokes despite different methods of anticoagulation.
First record of predation by the Andean white-eared opossum Didelphis pernigra on the red swamp crayfish Procambarus clarkii in Colombia
Authors: González-Ruiz Yesid de los Ángeles , Pimiento-Ortega Mabel Giovana , Herrera-Martínez Yimy
Published: December 2022

La zarigüeya de Virginia (Didelphis virginiana) ha sido identificada como depredador del cangrejo rojo de río (Procambarus clarkii) en Norteamérica.  En las regiones en donde ha sido introducido este cangrejo se han identificado otras especies de mamíferos que lo integran en su dieta.  El presente trabajo es el primer registro de depredación de D. pernigra, especie endémica de la cordillera de los Andes, sobre el cangrejo exótico invasor P. clarkii en Colombia.  Se realizaron transectos de 100 m en bosque ribereño de la cuenca media del río Chicamocha, Colombia, en donde se recolectaron las heces y se registraron huellas, posteriormente se obtuvieron registros fotográficos de individuos de zarigüeya en la zona.  Las heces se pesaron, disolvieron y separaron en cajas de Petri.  Las huellas e individuos fotografiados se identificaron empleando bibliografía especializada.  En las heces se encontraron estructuras que permitieron identificar, 5 individuos de la especie P. clarkii, un odonato y semillas de Poaceae.  Las huellas y ejemplares fotografiados corresponden a la especie D. pernigra, una especie registrada previamente en la región.  La colonización y reproducción de P. clarkii representa una nueva oferta de recursos que la especie D. pernigra ha integrado a su dieta.  La depredación de P. clarkii por parte de D. pernigra puede estar relacionado con el comportamiento nocturno de las 2 especies, que aumenta la posibilidad de depredación.  Probablemente las especies del género Didelphis, en Sudamérica, puedan modificar su dieta, si aumenta el área de invasión de P. clarkii.
Multimodalidade e Ensino Remoto: uma análise dos significados multimodais das atividades realizadas em Ambientes Virtuais de Aprendizagem
Authors: Rangel da Costa Paula Cristina , Dos Reis da Fonseca Lucas Eduardo
Published: December 2022

Assolado pela pandemia de COVID-19, o contexto de ensino global precisou ser alterado. O que era físico, passou a ser virtual e, nesse momento, torna-se latente uma das questões relacionadas aos contextos de multiletramentos que já vinha sido amplamente debatida: a multimodalidade (KALANTIZIS, 2020). Por meio da análise das atividades de dois ambientes virtuais de aprendizagem, de Instituições Públicas de Ensino, este artigo aborda os sentidos gerados nessas atividades e realiza uma coleta de dados a fim de compreender quais dos sentidos multimodais são mais produtivos na relação de ensino-aprendizagem. Desta forma, o presente estudo contribui para o entendimento de quais práticas multimodais são bem-sucedidas dentro do contexto abordado e o que pode ser incorporado às relações de ensino pós-pandêmicas.
ÍNDICES DA ADERÊNCIA DO INTÉRPRETE À METODOLOGIA DO DIREITO CIVIL-CONSTITUCIONAL/ SIGNS OF THE INTERPRETER’S ADHERING TO THE CONSTITUTIONALIZED PRIVATE LAW METHOD
Authors: Souza Eduardo Nunes de
Published: December 2022

Resumo: O presente artigo dedica-se a abordar alguns equívocos comuns acerca da metodologia civil-constitucional, em particular certos procedimentos interpretativos indevidamente atribuídos a essa escola hermenêutica. Parte-se, em primeiro lugar, da relevância da valorização do dado normativo pelo intérprete, analisando-se, em seguida, o papel e os limites da subsunção na perspectiva civil-constitucional e, ainda, a inevitabilidade da ponderação diante da complexidade de fontes normativas do sistema.Palavras-chave: Direito civil-constitucional. Hermenêutica jurídica. Análise funcional do direito. Unidade do ordenamento. Abstract: The article that follows is devoted to addressing some common misconceptions about the constitutionalized private law methodology, in particular certain interpretative procedures unduly attributed to this hermeneutical school. It departs from the relevance of the valorization of positive norms by the interpreter and then analyses the role and the limits of subsumption in the civil-constitutional perspective, as well as the inevitability of the weighing before the complexity of legal sources.Keywords: Constitutionalized private law. Legal hermeneutics. Functional legal analysis. Unity of the legal system.
CONSTITUIÇÃO ECONÔMICA E DESENVOLVIMENTO: A POLÍTICA ECONÔMICA BRASILEIRA DE 1995 A 2018 / ECONOMIC CONSTITUTION AND DEVELOPMENT: THE BRAZILIAN ECONOMIC POLICY FROM 1995 TO 2018
Authors: Lopes Maria Eduarda Olímpio , Lelis Davi Augusto Santana de
Published: December 2022

Resumo: O artigo analisa as políticas econômicas adotadas pelos Presidentes Fernando Henrique Cardoso, Luís Inácio Lula da Silva, Dilma Rousseff e Michel Temer, no período de 1995 a 2018, e sua relação com a Constituição Econômica. O problema da pesquisa está em compreender se tais políticas cumprem a ordem econômica da Constituição de 1988, respeitando o dirigismo constitucional e garantindo a busca pelo desenvolvimento. A Constituição de 1988 recepciona uma pluralidade ideológica, que permite políticas voltadas tanto para o aspecto financeiro neoliberal como para o viés econômico social. Para concretização constitucional enquanto unidade, as ações estatais devem passar pelo filtro hermenêutico da ideologia constitucionalmente adotada que ressignifica, no texto constitucional, os fundamentos das ideologias econômicas puras. Como resultado, constata-se que a Constituição Econômica recepciona ambiguidade ideológica e políticas econômicas de diversas ideologias. Conclui-se que mesmo sendo recebidas pela Constituição Econômica, as políticas econômicas do período analisado não implementaram processo de desenvolvimento por completo no Brasil, falhando assim em desempenhar a ideologia constitucionalmente adotada e em alcançar os objetivos dirigentes da Constituição de 1988. Palavras-chave: Políticas Econômicas; Constituição Econômica; Constituição Dirigente; Ideologia Constitucionalmente Adotada; Desenvolvimento. Abstract: The article analyzes the economic policies adopted by Presidents Fernando Henrique Cardoso, Luís Inácio Lula da Silva, Dilma Rousseff and Michel Temer, from 1995 to 2018, and their relationship with the Economic Constitution. The research problem is to understand whether such policies comply with the economic order of the 1988 Constitution, respecting constitutional leadership and guaranteeing the search for development. The 1988 Constitution welcomes an ideological plurality, which allows policies aimed at both the neoliberal financial aspect and the social economic bias. For constitutional concretization as a unit, state actions must pass through the hermeneutic filter of the constitutionally adopted ideology that resignifies, in the constitutional text, the foundations of pure economic ideologies. As a result, it appears that the Economic Constitution receives ideological ambiguity and economic policies from different ideologies. It is concluded that even though they were received by the Economic Constitution, the economic policies of the period analyzed did not fully implement the development process in Brazil, thus failing to carry out the constitutionally adopted ideology and to achieve the guiding objectives of the 1988 Constitution.Keywords: Economic Policies; Economic Constitution; Governing Constitution; Constitutionally Adopted Ideology; Development.
GOVERNO DIGITAL: POLÍTICA PÚBLICA, NORMAS E ARRANJOS INSTITUCIONAIS NO REGIME FEDERATIVO BRASILEIRO: A EDIÇÃO DA LEI FEDERAL N. º 14.129/2021 E O DESENVOLVIMENTO DA POLÍTICA NACIONAL DE GOVERNO DIGITAL / DIGITAL GOVERNMENT: PUBLIC POLICY, RULES AND INSTITUTIONAL ARRANGEMENTS IN THE BRAZILIAN FEDERATIVE REGIME. THE NEW FEDERAL LAW 14.129/2021 AND THE DEVELOPMENT OF A NATIONAL DIGITAL GOVERNMENT POLICY
Authors: Baptista Patrícia , Antoun Leonardo
Published: December 2022

Resumo: O artigo apresenta o governo digital sob a perspectiva de política pública, de sistema normativo e de arranjo institucional. Identifica normas e arranjos institucionais na política desenhada pelo governo federal brasileiro. Considera o ponto de vista das unidades da federação, para indicar a necessidade de integração federativa com preservação da autonomia local em face do protagonismo federal. E, por último, discorre sobre as virtudes, os riscos e os desafios para os entes da federação no desenvolvimento da política de governo digital.Palavras-chave: Governo digital. Governo eletrônico. Política pública. Sistema normativo. Arranjo institucional. Regime federativo. Estados-membros. Autonomia federativa. Proteção de dados. Transparência. Eficiência. Privacidade. Coordenação interfederativa. Desigualdade digital. Abstract: The article explores the idea of digital government conceived as a public policy, a regulatory system and an institutional arrangement. It identifies norms and institutional arrangements in the policy designed by the Brazilian federal government. And in regard of the federation units, it indicates the need for federative integration with preservation of local autonomy in the face of federal protagonism. And, finally, it discusses the virtues, risks and challenges in the development of digital government policy.Keywords: Digital government. Electronic government. Public policy. Regulatory system. Institutional arrangement. Federative system. States-members. Federative autonomy. Data protection. Transparency. Efficiency. Privacy. Inter-federative coordination. Digital inequality.
Política externa da UE para o leste pós-Guerra Fria: mudanças de rota no contexto da invasão da Ucrânia | EU foreign policy for the post-Cold War east: Route changes in the context of the invasion of Ukraine
Authors: Tostes Ana Paula Balthazar
Published: December 2022

A arquitetura institucional da UE gerou uma envergadura de actorness no contexto global (Hettne; Söderbaum, 2005) e levou a investimentos em políticas de vizinhança, para expandir seus valores e princípios comunitários no seu entorno (Lucarelli; Manners, 2006). Desde o alargamento da União para o leste, foram lançadas a Política Europeia de Vizinhança e a Parceria Oriental, como orientações pragmáticas de sua política externa para a região de disputa de influência com a Rússia desde o fim da Guerra Fria. O artigo busca contribuir com uma análise deste cenário de contendas e interdependência, em que condições de tolerância sustentam “conflitos congelados” (Coyle 2019; European Parliament, 2016) na região. Especialmente, o caso da Ucrânia oferece instrumentos de análise sobre arranjos e colapso de negociações baseadas em tensões e interesses alinhados aos diferentes projetos políticos representados pela Rússia e UE, e busca oferecer elementos históricos e políticos para o exame sobre condicionantes e desdobramentos da guerra.Palavras-chave: Política Externa da UE; Crise na Ucrânia; conflito congelado.ABSTRACTThe institutional architecture of the EU has generated a scale of actorness in the global context (Hettne; Söderbaum, 2005) and has led to investments in neighborhood policies to expand its community values and principles in its surroundings (Lucarelli; Manners, 2006). Since the enlargement of the Union to the east, the European Neighborhood Policy and the Eastern Partnership were launched, as pragmatic guidelines of its foreign policy for the region of Influence dispute with Russia since the end of the Cold War. The article seeks to contribute to an analysis of this scenario of disputes and interdependence, in which conditions of tolerance sustain “frozen conflicts” (Coyle 2019; European Parliament, 2016) in the region. In particular, the case of Ukraine offers tools for analyzing the arrangements and collapse of negotiations based on tensions and interests aligned with the different political projects represented by Russia and the EU, and seeks to offer historical and political elements for the examination of the constraints and unfolding of the war. Keywords: EU Foreign Policy; Crisis in Ukraine; frozen conflict. Recebido em: 31 mai. 2022 | Aceito em: 29 nov. 2022.