bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Emotional Maturity on Human Rights Action Intentions Among Celebrities Victimized by Sexual Harassment
Authors:   Korea Safety Culture Society, Lee Won June
Published: January 2025

This study investigates the impact of emotional maturity on intentions to engage in human rights actions for celebrities who have experienced sexual harassment, with a focus on the dual mediating roles of perceived physical attractiveness halo and human rights awareness, alongside moderating effects of gender and generational differences (pre-MZ vs. MZ generation). Data were gathered from a nationwide sample of 624 adults aged 25 to 59 and analyzed using structural equation modeling with AMOS and Mplus. Results indicate that while women show higher human rights awareness than men regarding sexually harassed celebrities, gender differences are not observed in human rights action intentions. Additionally, the pre-MZ generation demonstrates higher human rights awareness compared to the MZ generation, with no significant generational difference in action intentions. Emotional maturity positively correlates with human rights action intentions across genders and within the MZ generation, mediated in part by increased human rights awareness. For the pre-MZ generation, emotional maturity indirectly affects action intentions via full mediation through human rights awareness. Finally, among women and the MZ generation, heightened perception of the physical attractiveness halo effect weakens the positive impact of emotional maturity on action intentions, illustrating this perception’s mediating effect. No similar effect is found in men or the pre-MZ generation, underscoring the moderating role of gender and generational characteristics. Practical implications of these findings are discussed.
ANALISIS KETEBALAN SHELL UNTUK MENENTUKAN LAJU KOROSI DAN SISA UMUR TANGKI T-126 PPSDM MIGAS CEPU
Authors: Muhammad Abu Nashor , Novianto Hernawan
Published: January 2025

Penelitian ini bertujuan untuk mengevaluasi kondisi dan performa Tangki T-126 di PPSDM Migas Cepu dengan menganalisis ketebalan shell untuk menentukan laju korosi dan sisa umur tangki. Tangki T-126 digunakan untuk menyimpan produk Solar dan telah beroperasi sejak tahun 1984. Berdasarkan pengukuran di lapangan dan perbandingan dengan inspeksi sebelumnya, ditemukan penurunan ketebalan shell yang signifikan dari inspeksi sebelumnya. Hasil perhitungan menunjukkan laju korosi sebesar 0,05714 mm/tahun pada course 1 dan 0,02857 mm/tahun pada course 2 dan 3, dengan sisa umur masing-masing 20 tahun, 75 tahun, dan 79 tahun. Penelitian ini menekankan pentingnya inspeksi dan pemeliharaan rutin untuk memastikan kelangsungan operasi tangki. Dengan memahami laju korosi dan sisa umur tangki, perusahaan dapat mengoptimalkan strategi pemeliharaan dan mengurangi risiko kegagalan operasional yang dapat berdampak negatif pada produksi dan keselamatan.
Long-term follow-up result of short metaphyseal femoral stem in primary total hip arthroplasty: A retrospective study
Authors: Kumar Manoj , Sharma Ayush , Ksheerasagar Vivek P , Ghosh Akash K , Lal Mukund
Published: January 2025

BACKGROUND

Total hip arthroplasty (THA) has increased along with an increasing demand for improved quality of life. Combined with prolonged life expectancy, the number of revision surgeries is expected to increase. Stress shielding is a significant issue with traditional femoral stems used in THA, making revision surgeries particularly challenging in younger patients. This has sparked renewed interest in studying safety and functional outcomes of short metaphyseal femoral stems, which have the potential to alleviate these challenges and simplify revision surgeries.

AIM

To evaluate the long-term outcomes of short-stem THA.

METHODS

A total of 124 hips that underwent THA using the short femoral stem (TRILOCK® Depuy) between May 2006 and November 2008 were included in this study. Patients were followed for a period of 15 years. Outcomes were assessed in terms of pain relief, hip joint range of motion, improvement in mobility, and functional outcomes using the modified Harris Hip Score, Oxford hip score, and Western Ontario and McMaster Universities Osteoarthritis index score.

RESULTS

A total of 124 hips in 98 patients were evaluated. Significant improvements in functional outcomes were observed over the 15-year follow-up period, with no cases of subsidence, implant loosening, or complications necessitating revision surgery. The only complication reported was heterotopic ossification in 1 patient.

CONCLUSION

Short metaphyseal stems provide better functional outcomes with early mobilization, and its long-term follow-up without subsidence, implant loosening, or proximal femoral bone loss simplifies revision surgery in younger patients.
Limited evidence to support demineralized bone matrix in foot and ankle surgical procedures: A systematic review
Authors: Hartman Hayden , Butler James J , Calton Megan , Lin Charles C , Rettig Samantha , Tishelman Jared C , Krebsbach Sebastian , Randall Grace W , Kennedy John G
Published: January 2025

BACKGROUND

Demineralized bone matrix (DBM) is a commonly utilized allogenic bone graft substitute to promote osseous union. However, little is known regarding outcomes following DBM utilization in foot and ankle surgical procedures.

AIM

To evaluate the clinical and radiographic outcomes following DBM as a biological adjunct in foot and ankle surgical procedures.

METHODS

During May 2023, the PubMed, EMBASE and Cochrane library databases were systematically reviewed to identify clinical studies examining outcomes following DBM for the management of various foot and ankle pathologies. Data regarding study characteristics, patient demographics, subjective clinical outcomes, radiological outcomes, complications, and failure rates were extracted and analyzed. In addition, the level of evidence (LOE) and quality of evidence (QOE) for each individual study was also assessed. Thirteen studies were included in this review.

RESULTS

In total, 363 patients (397 ankles and feet) received DBM as part of their surgical procedure at a weighted mean follow-up time of 20.8 ± 9.2 months. The most common procedure performed was ankle arthrodesis in 94 patients (25.9%). Other procedures performed included hindfoot fusion, 1st metatarsophalangeal joint arthrodesis, 5th metatarsal intramedullary screw fixation, hallux valgus correction, osteochondral lesion of the talus repair and unicameral talar cyst resection. The osseous union rate in the ankle and hindfoot arthrodesis cohort, base of the 5th metatarsal cohort, and calcaneal fracture cohort was 85.6%, 100%, and 100%, respectively. The weighted mean visual analog scale in the osteochondral lesions of the talus cohort improved from a pre-operative score of 7.6 ± 0.1 to a post-operative score of 0.4 ± 0.1. The overall complication rate was 27.2%, the most common of which was non-union (8.8%). There were 43 failures (10.8%) all of which warranted a further surgical procedure.

CONCLUSION

This current systematic review demonstrated that the utilization of DBM in foot and ankle surgical procedures led to satisfactory osseous union rates with favorable wound complication rates. Excellent outcomes were observed in patients undergoing fracture fixation augmented with DBM, with mixed evidence supporting the routine use of DBM in fusion procedures of the ankle and hindfoot. However, the low LOE together with the low QOE and significant heterogeneity between the included studies reinforces the need for randomized control trials to be conducted to identify the optimal role of DBM in the setting of foot and ankle surgical procedures.
Pengembangan dan Validasi Media Video Pembelajaran Materi Zat dan Perubahannya untuk Siswa SMP
Authors: Sari Fatmi Intan , Aththibby Arif Rahman , Pratiwi Dasrieny
Published: January 2025

Era modern saat ini, penggunaan teknologi di kelas sangat membantu proses pembelajaran. Salah satu teknologi yang digunakan dalam pembelajaran adalah video pembelajaran untuk membantu siswa lebih memahami ide-ide abstrak. Tujuan dari riset ini adalah untuk membuat video pembelajaran sains yang akan diajarkan kepada siswa kelas tujuh di SMP Muhammadiyah Ahmad Dahlan Metro tentang zat dan perubahannya tersebut berubah. Model ADDIE, yang terdiri dari lima Langkah yitu analisis, desain, pengembangan, implementasi, dan evaluasi adalah metodologi penelitian dan pengembangan yang digunakan. Kuesioner angket respon siswa dan lembar kuesioner validasi yang memverifikasi kesesuaian media dan materi adalah alat yang digunakan untuk mengukur kevalidan dan respon siswa terhadap media video pembelajaran yang dikembangkan. Rumus uji Aiken digunakan untuk menentukan keabsahan ahli media dan materi. Tiga validator ahli media yang berbeda menghasilkan validasi media sebesar 0.86 (validitas sangat tinggi) dan tiga validator ahli materi menghasilkan validasi materi sebesar 0.87 (validitas sangat tinggi). Uji coba dengan 27 siswa yang menjadi subjek penelitian mengungkapkan bahwa 86.36% respon siswa termasuk dalam kategori "sangat baik". Berdasarkan hasil penelitian dapat dikatakan bahwa perangkat pembelajaran berupa video pembelajaran tentang zat dan perubahannya sangat valid dan dapat direspon positif oleh siswa kelas VII SMP Muhammadiyah Ahmad Dahlan Metro.
Price prediction of dual-listed stocks with RF and LSTM algorithms: NYSE and BIST comparison
Authors: Cici Karaboğa Emine Nihan , Şekeroğlu Gamze , Kızıloğlu Esra , Karaboğa Kazım , Acılar Ayse Merve
Published: January 2025

Companies are looking for ways to access capital from developed markets instead of local markets to find financing. While some companies use debt instruments for this purpose, others use equity financing methods. One of the techniques used in equity financing is the simultaneous registration of shares on national and foreign stock exchanges, also known as the dual-registration method. Investors entering international markets by investing in dual-registered shares is important for companies to gain capital. However, another important issue for those investing in stocks is the ability to gain capital through accurate prediction of price movements. The aim of this study is to predict the prices of Turkcell stocks traded on Borsa Istanbul and the New York Stock Exchange (NYSE) using machine learning and deep learning methodologies. The results of the analyses conducted with the Random Forest Regressor and Long Short-Term Memory algorithms, which are machine learning and deep learning algorithms, respectively, showed that both algorithms exhibited a lower error rate in predicting the closing prices of Turkcell stocks on the NYSE.
Exploring the Role of Sentence-Final Particles in Spoken Cantonese: A Comparative Study Based on the POS-based Dependency Networks
Authors: Chen Yixi , Yan Jianwei
Published: January 2025

Sentence-final particles (SFPs) are pervasive in spoken Cantonese for expressing speakers’ attitudes. This study explores the global and local features of SFPs in both spoken Cantonese and Mandarin Chinese using two part-of-speech-based (POS-based) dependency networks. Results show that (1) globally, spoken Cantonese and Mandarin Chinese networks exhibit centralization and scale-free properties, reflecting the communication efficiency of human languages. However, spoken Cantonese manifests weaker centralization properties, as demonstrated by the diversity of its edges. Moreover, SFPs in spoken Cantonese have a greater degree and in-degree than those in Mandarin Chinese, indicating a stronger ability to form syntactic connections with other POSs in the language structure. (2) locally, Cantonese SFPs display more extensive mood expression devices, notably differing in PART-NOUN (discourse:sp), PART-ADV and PART-ADJ dependencies compared to Mandarin Chinese. Additionally, specific examples illustrate how Cantonese SFP usage differs from Mandarin Chinese, showcasing their distinct discourse functions. The findings suggest that communication efficiency is a cross-lingual universal, while spoken Cantonese is distinctive in its use of diverse SFPs to express moods. This study may shed new light on adapting the complex network approach to explore the similarities and differences across human languages.
Decoding online literature: A Quantitative Analysis of Language Features in Chinese Online Literature
Authors: Wang Yubo , Wang Lüyuan , Wang Xuanqi , Xie Fang
Published: January 2025

Chinese online literature has rapidly gained popularity, displaying characteristics that differ from traditional literature, and has now become an important and unique literary genre. Chinese readers of online literature account for nearly half of the total number of Chinese internet users, approximately 537 million. This study aims to explore the linguistic characteristics of online literature through a combination of qualitative and quantitative methods. The study builds a large-scale corpus from the largest Chinese online literature website Qidian, focusing on six quantitative linguistic indicators: word frequency, lexical richness, lexical density, word vectors, punctuation distribution, and average paragraph length. Additionally, three text mining indicators—thematic concentration, information entropy, and authorial perspective—are introduced. The findings reveal that online literature features a casual and informal language style, characterized by a high frequency of function words, shorter average paragraph lengths, and significant reliance on dialogue. Furthermore, the thematic concentration is generally low, which is related to the verbosity of online works and their emphasis on narrative flow rather than detailed descriptions. Overall, this paper provides empirical data to enhance the understanding of the linguistic features of online literature and suggesting that future research could adopt broader metrics and more comprehensive text mining techniques.
Water Quality Status and Primary Productivity of Anchuthengu - Akathumuri Backwater, System in Southern Kerala
Authors: Rakhi, R.  , G.S. Babitha , Sheeba S.
Published: January 2025

Water quality assessment is crucial for evaluating its sustainable use by dependent biota. The present study investigates physico-chemical parameters and primary productivity of the Anchuthengu - Akathumuri backwater (8° 39’ to 8° 44”N latitude and 76° 45’ to 76° 47”E longitude) located in southern Kerala from March to August 2022. Significant spatial and temporal fluctuations were observed in temperature, salinity, phosphate-phosphorus, nitrate-nitrogen, and nitrite-nitrogen. Dissolved CO2 , alkalinity, BOD, DO, and pH levels remained within optimal ranges. Reduced transparency during monsoon months was attributed to turbidity and low solar radiation, accompanied by decreased salinity (0-5). Fluctuating levels of sulphate (10-25 mg/l), nitrate nitrogen (4-5 mg/l), nitrite nitrogen (0.1-0.2 mg/l), and phosphate (0.2-0.3 mg/l) were likely influenced by irregular monsoons and anthropogenic activities. Seasonal analysis of Gross Primary Productivity (GPP) and Net Primary Productivity (NPP) indicated significant variation among sampling stations. This study provides insights that can guide the implementation of mitigating measures to preserve the health of the backwater ecosystem.
Constraints Faced by Farmers in Adoption of Integrated Farming System in Cuddalore District of Tamil Nadu, India
Authors: Kumar P. Sanjith , Ramesh P.  , Vengatesan D.  , C. Prabakar
Published: January 2025

Integrated farming system play a vital role in transforming the Indian economy by boosting rural livelihoods, enhancing food security and contributing to a more sustainable and equitable society. This study explores the constraints faced by farmers in adopting Integrated Farming Systems (IFS) in the Cuddalore district of Tamil Nadu. The adoption of IFS is crucial for enhancing agricultural productivity, sustainability, and income diversification. However, various challenges hinder its implementation among local farmers. The research utilizes a mixed methods approach, incorporating surveys, interviews, and focus group discussions with farmers. The constraints were classified into production, situational, financial and marketing constraints. The respondents were asked to mention the various constraints faced by the farmers in adoption of integrated farming system. The constraints were ranked by using Garrett Ranking method. Findings reveal a complex interplay of factors hindering IFS adoption, top constraints under each dimension they are non-availability of quality seed, planting materials/breed/species (75.22 GMS), uneven distribution of rainfall (76.02 GMS), loan disbursement procedure is cumbersome (77.44 GMS) and exploitation by the middleman (78.90 GMS). This study highlights the need for targeted interventions to address these constraints and promote the successful implementation of IFS in Cuddalore district. The findings reveal that while farmers recognize the potential benefits of IFS, a lack of supportive infrastructure and institutional frameworks significantly impedes their willingness to adopt these practices. Recommendations for policy interventions and capacitybuilding initiatives are discussed to promote the successful integration of IFS in the region.
Impact of Integrated Nutrient Management on Yield and Economic Returns in Mustard (Brassica juncea L.)
Authors: Chand Priyanka , Sharma Jaidev , Kanaujiya Pradeep Kumar , Rajput Pradeep , Parashar Aman
Published: January 2025

A field experiment was conducted during the Rabi seasons of 2021-2022 and 2022-2023 to evaluate the economic feasibility of Integrated Nutrient Management (INM) on the yield and economic returns of mustard (Brassica juncea L.). The experiment included fourteen treatments and was replicated three times in a randomized block design (RBD). In the 2021-2022 season, the highest seed yield of 21.46 q/ha was recorded in treatment T10 (50% NPK + vermicompost @ 5 t/ha + ZnSO4 @ 40 kg + Azotobacter), while the lowest seed yield of 9.11 q/ha was observed in T1 (Farmer’s practice). Similarly, in the 2022-2023 season, T10 again recorded the highest seed yield of 21.86 q/ha, whereas T1 showed the lowest yield of 9.35 q/ha. The stover yield followed a similar trend, with T10 exhibiting the highest yields of 51.36 q/ha in 2021-2022 and 52.06 q/ha in 2022-2023. In contrast, T1 had the lowest stover yields, recording 27.41 q/ha and 27.85 q/ha in the respective years. From an economic perspective, in the 2021-2022 season, the T9 treatment (75% NPK + vermicompost @ 2.5 t/ha + ZnSO4 @ 40 kg/ha + Azotobacter) proved to be the most economically feasible. It incurred a cultivation cost of Rs. 33,810, yielding a gross income of Rs. 105,798 and a net income of Rs. 71,988 per hectare. This was closely followed by T10 (50% NPK + vermicompost @ 5 t/ha + ZnSO4 @ 40 kg/ ha + Azotobacter), with a cultivation cost of Rs. 40,060, a gross income of Rs. 110,064, and a net income of Rs. 70,004 per hectare. In the 2022-2023 season, the T9 treatment continued to show favourable economic results, with a cultivation cost of Rs. 33,810, a gross income of Rs. 116,624, and a net income of Rs. 82,814 per hectare. Similarly, T10 recorded a cultivation cost of Rs. 40,060, generating a gross income of Rs. 120,827 and a net income of Rs. 80,767 per hectare. The benefit-cost (B-C) ratio further highlighted the economic viability of the treatments. In 2021-2022, T9 had a B-C ratio of 2.13, while T10 recorded a ratio of 1.75. In the 2022- 2023 season, the B-C ratio for T9 increased to 2.44, and for T10, it rose to 2.02. Overall, these results indicate that the T9 treatment (75% NPK + vermicompost @ 2.5 t/ha + ZnSO4 @ 40 kg/ha + Azotobacter) was the most economically viable option for mustard cultivation across both years, offering higher net returns and a superior B-C ratio.
Assessing the Impact of Anthropogenic Activities on Biodiversity and Ecosystem in the Western Ghats
Authors: Philip Amal , K Thomas Deepa
Published: January 2025

Human activity poses serious risks to the Western Ghats, a UNESCO hotspot for biodiversity. This study looks at how human activity affects the ecosystem health and biodiversity in this environmentally delicate area. Changes in land use, such as deforestation for plantations, agriculture, and infrastructure development, will be examined in the research. The assessment will focus on how these activities jeopardize endemic species, cause habitat disruption, and fragment ecosystems. Acclaimed for its ability to unite economic growth and conservation, ecotourism is becoming recognized as a potentially bright future for areas in the Western Ghats, known for their abundant biodiversity. These abstract analyses about how the growth of ecotourism has affected the way of life for the locals in the region. It looks at the possible advantages, such generating cash and jobs, as well as the possible disadvantages, including resource pressure and displacement. A UNESCO-designated hotspot for biodiversity, the Western Ghats are home to remarkable endemism and species richness. However, a variety of human activities pose serious challenges to this natural treasure trove. The influence of human pressures on the Western Ghats’ biodiversity and ecological function is examined in this research. Certain species are on the verge of extinction due to overfishing and poaching. Water sources are contaminated by industrial effluents, agricultural runoff, and overuse of pesticides, which impacts aquatic life and interferes with ecosystem functions. We will investigate the ways in which habitat loss, species decline, and disruption of ecosystem services are caused by deforestation, urbanization, agriculture, and other human-driven processes. The aim is to comprehend how the Western Ghats’ natural integrity may be preserved while local populations are empowered through ecotourism.
Therapeutic Benefit of Nadayoga for The Management of Insomnia
Authors: Dwivedi Ayushi , Srivastava Mona , S. Byadgi Parameswarappa
Published: January 2025

Insomnia, a common sleep disorder characterized by difficulty falling and staying asleep, affects millions worldwide, impacting overall health and quality of life. Traditional treatment options include pharmacological and behavioral therapies, but alternative approaches such as yoga have gained attention for their holistic benefits. Nadayoga, a branch of yoga focusing on sound and music, shows promise as a therapeutic intervention for insomnia. This paper explores the efficacy of Nadayoga in managing insomnia, examining its underlying mechanisms, clinical evidence, and practical applications.
Method: Through an extensive review of literature and empirical studies, we uncover the profound benefit of Nadayoga on Insomnia Furthermore, we investigate the physiological and psychological mechanisms underlying these effects, shedding light on the intricate interplay between the mind and body in the context of yoga practice. Our findings emphasize the potential of yoga as a holistic approach to address a wide range of health issues, from physical ailments to mental stressors. For the making of this article, we have compiled information from various texts Pubmed, web of sciences, Google Scholar and various references.
In conclusion, the synthesis of scientific evidence and traditional wisdom underscores the significance of Nadayoga as a valuable tool in addressing sleep-related issues. It extends an invitation to individuals grappling with sleep disturbances to embrace a holistic approach that harmonizes ancient practices with contemporary understanding.
The Concept of Liberation (Moksha) in Indian Philosophy: An Analysis
Authors: Upadhyay Sonam , sanwal Kiran , P.K. Goswami Prof.
Published: January 2025

Indian philosophy extensively explores the concept of liberation (moksha), regarded as the ultimate goal of human existence. Moksha signifies the cessation of the cycle of birth and death (samsara) and the realization of one’s true self, free from ignorance (avidya) and suffering (dukkha). This paper delves into the diverse interpretations of moksha across major philosophical traditions such as Vedanta, Samkhya, Yoga, Jainism, and Buddhism. While Vedanta emphasizes self-realization through the knowledge of Brahman, Samkhya and Yoga focus on detachment and the separation of Purusha from Prakriti. Jainism advocates for ethical living and spiritual purity, while Buddhism aims for nirvana through the cessation of desires. The analysis underscores the philosophical underpinnings, methods of attainment, and the implications of moksha on ethics, metaphysics, and human well-being. This study bridges classical texts and contemporary relevance, providing a holistic understanding of moksha as a transformative spiritual ideal.
Including DOIs in RSS Feeds: Implementation
Authors: Fenner Martin
Published: January 2025

Last week I wrote about the options we have for including DOIs in RSS feeds. This week is implementation time. Starting today, the Atom feed of this blog includes the DOI in the Atom metadata field.
Pharmacist-led smoking cessation programs: A comprehensive review of effectiveness, implementation models, and future directions
Authors: Oluwaseyi Inumidun Alli  , Samuel Ajibola Dada
Published: January 2025

Pharmacist-led smoking cessation programs have emerged as effective interventions in addressing the global tobacco epidemic, leveraging the accessibility and expertise of pharmacists to provide tailored behavioral counseling, pharmacological support, and follow-up care. This review examines the effectiveness of these programs, highlighting their ability to achieve higher quit rates, improved patient satisfaction, and cost-effectiveness compared to traditional methods. Various implementation models, including those in community pharmacies, hospital settings, and telehealth platforms, are explored, along with the challenges of scaling these interventions, such as limited awareness, training gaps, and inadequate reimbursement. Future directions emphasize innovations in digital tools, personalized medicine, artificial intelligence, and policy and funding support to enhance program reach and sustainability. Recommendations are provided for pharmacists, healthcare systems, and policymakers to address barriers, expand access, and foster collaboration, ultimately integrating pharmacist-led smoking cessation into mainstream healthcare as a critical strategy for tobacco control.
Eventos trombóticos associados às vacinas contra Covid-19: revisão integrativa
Authors: Pimentel Rogério de Araújo , Arantes Ana Paula Felix , Costa Matheus André Ribeiro da , Sudré Tamyris Mendes de Faria , Oliveira Deise Aparecida de Almeida Pires
Published: January 2025

A vacinação contra a Covid-19 desempenhou um papel crucial na mitigação da pandemia, levando a uma diminuição significativa nas hospitalizações e mortes. No entanto, surgiram relatos de eventos trombóticos raros, como a síndrome de trombose com trombocitopenia induzida pela vacina (VITT), especialmente com vacinas de vetor viral. Estudos sugerem uma relação com essas vacinas, em particular para mulheres jovens, enquanto as vacinas de mRNA, como Pfizer e Moderna, apresentam riscos bem menores. A VITT está relacionada à produção de anticorpos contra o fator plaquetário 4, resultando em ativação plaquetária. Dados recentes indicam que a primeira dose de vacinas adenovirais está mais ligada a esses eventos, embora ainda sejam muito raros. O tratamento de tais eventos segue protocolos convencionais, com variações nas diretrizes entre países. Comparações entre tipos de vacinas enfatizam a necessidade de avaliar o risco-benefício para diferentes grupos populacionais, destacando a segurança e eficácia das vacinas de mRNA. O estudo propõe uma revisão integrativa sobre essas questões.
Conhecimento local e as vias de transmissão cultural no uso de plantas medicinais no município de Buritirana, Maranhão
Authors: Silva João Lucas Azevedo da , Lima Graziela da Costa , Nogueira Francinete da Silva , Silva Kaio de Moura , Gonçalves Wemerson de Carvalho , Carvalho Niara Porto de
Published: January 2025

O uso de plantas medicinais no tratamento de doenças é uma prática bastante comum entre pessoas que residem em zonas rurais. Os saberes que essas pessoas têm vem sofrendo enorme desvalorização frente a diminuição das vias de transmissão desse conhecimento local. No estado do Maranhão, estudos sobre plantas medicinais têm recebido um maior enfoque nos últimos anos, contudo ainda são escassos e pontuais quando se trata do percentual de estudos versus o número de municípios analisados e por ser um estado rico em diversidade vegetacional e cultural. Desta forma, objetivou-se realizar o levantamento das etnoespécies utilizadas como medicinais pelas comunidades delimitadas no zoneamento rural no município de Buritirana –Maranhão. A coleta das espécies indicadas como medicinais foi realizada por meio da técnica de turnê guiada. Foram realizados cálculos dos valores de importância relativa (IR), valor de uso (VU) e Fator de Consenso dos Informantes (FCI). A hortelã (Mentha spicata L.) se destacou como a espécie com maior VU= 0,72. A rota mais utilizada para transmissão do conhecimento local sobre essas plantas curandeiras, segundo os entrevistados, é a vertical (quando ensinado pelos pais). Com os dados obtidos foi possível catalogar uma variedade de plantas medicinais no município permitindo o registro do saber tradicional pelas comunidades.
Simulasi Rambu Lalu Lintas AR Real-Time untuk Edukasi Interaktif Berbasis Gamifikasi
Authors: Eva Handriyantini  , Bernard Dikson Gandawinata
Published: January 2025

Enhancing understanding and awareness of traffic safety is a critical challenge, particularly among younger generations. This study aims to develop a real-time Augmented Reality (AR)-based traffic sign simulation application integrated with gamification elements to improve user engagement and comprehension. The research employed a Research and Development (R&D) approach involving 30 respondents as application users. The development process included needs analysis, user interface design using a user-centered approach, implementation of markerless tracking technology, and integration of time-based challenges and virtual rewards as gamification elements. The testing results indicated a 30% improvement in post-test scores compared to pre-test scores, demonstrating the application's effectiveness in enhancing users' understanding of traffic signs. This application is not only relevant for formal education in schools but also holds potential as an innovative tool for traffic safety campaigns. The study supports the theory that the integration of AR and gamification can create engaging and effective learning experiences.
Dampak Migrasi TKW terhadap Pengasuhan Keluarga di Indramayu: Peran Remitan dalam Menyokong Kesejahteraan
Authors: Ahmad Ro’i Alfaza  , Bambang Yuniarto  , Ahmad Sururi
Published: January 2025

The migration of Indonesian Women Workers (TKW) significantly contributes to family economies through remittances but also creates social and emotional challenges. This study aims to analyze the impact of TKW migration on child-rearing patterns and the role of local communities in supporting their families in Indramayu. A qualitative approach using a case study method was employed, involving in-depth interviews, observations, and document analysis. The results reveal that remittances from TKW serve as the primary source of family income, yet the absence of mothers causes emotional gaps and changes in parenting patterns. Children are often cared for by grandparents or placed in Islamic boarding schools (pesantren), leading to varied effects on their education and discipline. Faith-based communities play a significant role in supporting TKW families, particularly through moral and social education. This study recommends strengthening the role of local communities and implementing social protection policies for TKW and their families to mitigate the negative impacts of migration.
Kegiatan Cooking Class dalam Meningkatkan Kemandirian dan Keterampilan Siswa
Authors: Faqih Faqih Hakim Hasibuan , Dira Puspita Sari
Published: January 2025

Student independence and skills are now a problem that can be solved. In today's digital age, student independence and skills must be increased. Based on the literature review carried out, researchers can conclude that cooking class is a fun activity for students and can increase students' independence and skills which are reflected in the cooking activities carried out by students with teachers at elementary schools. Through this study, it is hoped that teachers will be able to carry out cooking class activities for elementary school students in grades 1, 2 and 3 using ingredients available around them, and paying attention to safety elements for children. Parents at home can also involve their children in cooking activities at home, even though the children are still in the developmental stage so that cooking tasks at home can be adjusted to the child's development and safety. So that children become more independent and skilled in doing housework, especially cooking.
Revitalisasi Pendidikan Karakter KH. Hasyim Asy’ari dalam Kitab Adāb Al-‘Ālim Wa Al-Muta’allim
Authors: Syarif Maulidin  , Nurul Vazilatul Umayah  , Ulin Nuha
Published: January 2025

This research aims to examine the thoughts of K.H. Hasyim Asy'ari in the book Adāb Al-'Ālim Wa Al-Muta'allim is related to the revitalization of character education. The background to this research is based on the importance of character education in shaping the morality and integrity of the younger generation, especially in the context of Islamic education. The method used is library research with a qualitative approach, which collects data from the works of K.H. Hasyim Asy'ari and other relevant literature. The research results show that K.H.'s thinking Hasyim Asy'ari in this book contains character education values ​​that can be applied to improve the current education system, such as the importance of simplicity, honesty and moral awareness. This finding has the implication that K.H. Hasyim Asy'ari can be used as a basis for developing a character education curriculum based on Islamic values, in order to form a better generation in the future.
Consumo de alcohol durante el COVID-19 en Latinoamérica según edad y situación de empleo
Authors: Villanueva-Blasco Víctor José , Villanueva-Silvestre Verónica , Belda Ferri Lorena , Vázquez-Martínez Andrea , Isorna Folgar Manuel , Canay Roberto , Abad Villaverde Beatriz
Published: January 2025

Esta investigación evaluó el consumo de alcohol en población adulta Latinoamericana y
del Caribe latino durante el confinamiento por COVID-19, atendiendo a la edad y situ-
ación laboral. Diseño no probabilístico con muestreo por conveniencia, con una muestra
de 4975 participantes. Se analizó edad, situación laboral y consumo de alcohol durante el
confinamiento y retrospectivamente antes de la pandemia. Los resultados muestran que
independientemente del país, los jóvenes de 18-29 años disminuyeron el consumo durante
el confinamiento; mientras que el mayor aumento fue en adultos de 45-54 años. Los traba-
jadores a tiempo completo consumieron más que las personas desempleadas. Empleados
a tiempo completo y a tiempo parcial, disminuyeron su consumo durante el confinamiento.
Trabajadores por cuenta propia mostraron un consumo de alcohol significativamente supe-
rior al de empleados a tiempo completo y a tiempo parcial, durante el confinamiento. Es
importante impulsar políticas de prevención del consumo de alcohol en el ámbito laboral.
Drogas en prisiones: una exploración de su presencia desde la perspectiva de los reclusos
Authors: Segura Nieto Alejandro , Pons Diez Xavier
Published: January 2025

Esta investigación tiene como objetivo realizar una aproximación a la problemática del consumo de drogas en las prisiones. Se pretende recopilar datos acerca de la presencia de las drogas en las prisiones y sus formas de uso en ese contexto. Para ello, se construyó una entrevista semiestructurada que fue aplicada a una muestra de 22 personas que han pasado por alguna de las prisiones de la Comunidad Valenciana (España). Tras aplicar análisis de contenido con evaluación interjueces, los resultados revelan la existencia de disfuncionalidades en cuanto a la prevención y el control del consumo de drogas en las prisiones, reflejadas en la gran disponibilidad de drogas en prisión, el entorno estresante y la falta de intervención eficaz por parte de los trabajadores penitenciarios, todo lo cual sugiere que la prisión es un contexto con una elevada disponibilidad para el consumo.
Sex differences in alcohol and tobacco use in Ecuadorian college students
Authors: Vaca-Quintana Diego , Bassante Christian , Moreta-Herrera Rodrigo , Merlyn-Sacoto Marie-France , López-Barrionuevo Carlos , Porras Belén
Published: January 2025

This study aims to report levels, sex differences, and sex as a risk factor in alcohol and tobacco use among Ecuadorian college students. A descriptive and comparative method was employed. The sample consisted of 546 college students (69.1% women), aged between 17 and 41 years, from four universities located in the cities of Ambato and Quito. The results indicated low levels of alcohol and tobacco use, with significant sex differences showing higher consumption among men. Men were found to be 2.1 times more likely to consume alcohol and 3 times more likely to use tobacco compared to women. In conclusion, alcohol and tobacco use is a common behavior among the sample, with sex being a key factor in both the increase in consumption and the development of risky consumption patterns.
FREQUENCY OF MICROALBUMINURIA IN TYPE II DIABETES MELLITUS PATIENTS: A CROSS SECTIONAL STUDY
Authors: SAJJAD J , WAHAB S , HIDAYAT S , ZAHID U , ABDULLAH HA , MUSHEER Z
Published: January 2025

Microalbuminuria is an early marker of diabetic nephropathy and an important predictor of cardiovascular and renal complications in patients with Type II diabetes mellitus. Identifying its prevalence and associated risk factors is crucial for early intervention Objective: The objective of this study was to determine the frequency of microalbuminuria and its associated risk factors in patients with Type II diabetes mellitus. Methods: This cross-sectional study was carried out in the medical ward of a tertiary care hospital from March 2024 to September 2024. Two hundred fifty patients, aged 30 years or older, diagnosed with Type II diabetes, were selected. The presence of microalbuminuria was assessed using urine albumin-to-creatinine ratio measurements. Results: Mean age was 52.04 ± 12.311 years, gender-wise there were 152 males (60.8%) and 98 females (39.2%) patients. The frequency of microalbuminuria was 76 (30.4%). Microalbuminuria was notably associated with BMI, duration of diabetes, and the presence of hypertension, with significant associations observed (p < 0.05) for all these factors. Conclusion: Our study demonstrated that microalbuminuria was found in 30.4% of patients presenting with diabetes type II, with significant associations observed for hypertension, BMI, and the duration of diabetes.
NITROGEN PRIMING SOURCES AFFECT THE SEED GERMINATION, GROWTH AND FRUIT ATTRIBUTES OF BITTER GOURD
Authors: ANWAR M , WAHOCHO NA , MEMON NUN , KANDHRO MN , ABBAS T , TALPUR KH , JAMALI MF , KAKAR K
Published: January 2025

The production of bitter gourd is often hampered by low seed germination rates due to its hard seed coat, which leads to sluggish seed germination, poor stand establishment, and yield losses. Nutrient seed priming has emerged as a promising technique to overcome these challenges by enhancing seed vigor and germination performance, hence explored in bitter gourd. The study pursued a thorough assessment of the effects of seed priming with nitrogen sources (Urea and KNO3) on germination, growth, fruit characteristics, and shelf life of bitter gourd cultivars (Fighter and Palee). The treatments included unprimed seeds (Control), seed priming with tap water, seed priming with urea solution (1% and 2%), and seed priming with KNO3 solution (1% and 2%).  The results revealed that priming with KNO3 at 2% concentration emerged as the superior treatment across multiple growth parameters, yielding the highest germination rate (85.40%), longest vine length (179.34 cm), and most abundant leaf count vine-1 (298.89). This priming also led to a significant reduction in days to flowering and enhanced the fruiting phase, resulting in earlier fruit development (59.53 days), increased fruit length (22.80 cm), and the highest single fruit weight (104.87 g). The priming with KNO3 at 2% also showed promising results for fruit shelf-life characteristics and improved shelf life (6.07 days) and minimal weight loss (4.61%). Between the two varieties, 'Palee' consistently outperformed 'Fighter,' showcasing superior performance for all the attributes observed in the study. These findings highlight the significant role of priming in enhancing the germination, fruit characteristics and shelf life of bitter gourd.
Exploring the Metabolic and Mitogenic Potential of a Hyper-Stable Variant of FGF1
Authors:   University of Arkansas, Fayetteville, Starr Emma , Edirisinghe Oshadi ,   University of Arkansas, Fayetteville, Kumar Thallapuranam ,   University of Arkansas, Fayetteville
Published: January 2025

Fibroblast growth factors (FGFs) are a family of 22 human cytokines involved in critical cellular processes, such as proliferation, differentiation, metabolism, angiogenesis, tumor metastasis, and wound healing. Among these, fibroblast growth factor 1 (FGF1) possesses a powerful mitogenic potential as it can nonspecifically bind to all four FGF receptors. However, the therapeutic applications of FGF1 are hindered by its inherent thermal and proteolytic instability, especially at physiological temperatures. This is believed to be attributed to the heparin-binding pocket at the C-terminus, which contains numerous positively charged residues that repel each other. To combat this instability, FGF1 binds to a negatively charged glycosaminoglycan, heparin. Heparin is hypothesized to play a crucial role in FGF1 signal transduction and intracellular signaling.

To overcome the thermal instability of FGF1, a hyper-stable variant of FGF1 (hsFGF1) was engineered with five amino acid substitutions (R136E, K126N, Q54P, S61L, and H107S), including two mutations within the heparin-binding region. This variant maintains structural integrity with enhanced thermal and proteolytic stability, yet no longer depends on heparin for its activity. Differential scanning calorimetry revealed a substantial increase in thermal stability (ΔTm = 27°C) for hsFGF1 compared to wild-type FGF1 (wtFGF1). Furthermore, limited trypsin digestion assays showed that hsFGF1 exhibits significantly greater resistance to proteolytic cleavage, indicating a more compact and stable protein conformation. Despite its reduced heparin-binding affinity, hsFGF1 retains its mitogenic and metabolic functions. Remarkably, cells treated with hsFGF1 elicited an enhanced proliferation and increased glycolytic respiration compared to those treated with wtFGF1, suggesting that heparin is not critical for FGF1- mediated signaling. Our findings challenge the existing paradigm regarding heparin's role and provide novel insights into the structural and metabolic properties of FGF1. These findings hold significant promise for the development of FGF-based therapeutics targeting wound healing, diabetes, and obesity.
Isolation and molecular detection of Pasteurella multocida and Gallibacterium anatis in Poultry from Five Provinces in Iraq
Authors: Shaymaa Jameel Owaid  , A. H. Ulaiwi
Published: January 2025

The current study aimed at isolation and identification with molecular detection of Pasteurella multocida and Gallibacterium anatis from five provinces in Iraq. Samples were collected from 68-layer farms in different provinces (Baghdad, Diyala, Babylon, Salahuddin, and Wasit). Out of 12 swabs of suspected chicken cases, bacteriological diagnosis detected 5 isolates as Pasteurella multocida by using blood agar and biochemical tests, and out of 21 samples, only 6 isolates were Gallibacterium anatis using the same blood agar and biochemical tests. Additionally, the positive samples detected by RT- PCR technique was used to confirm the isolates. To conclude, Pasteurella multocida and Gallibacterium anatis were isolated bacteria from respiratory infections in layer poultry farms in Iraq.
Modeling Extreme Healthcare Costs Using the Neutrosophic Cauchy Distribution
Authors:   Department of Mathematics, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia, Afrah Afrah ,   School of Economics, Beijing technology and business university, Beijing, China, Amin Adnan
Published: January 2025

Real data modelling of extreme events, such as rainfall, temperature, financial costs is very important in neutrosophic statistical methods. The Cauchy distribution is one of statistical models used for modelling such extreme events in natural processes. In cases of imprecise data which most often involve vague, incomplete and ambiguous information, standard statistical methods cannot fully describe the spectrum of uncertainty. In this study, we have considered a new Cauchy distribution under neutrosophic context to deal with uncertain data. The proposed neutrosophic Cauchy distribution (NCD) may analysis extreme events data involving incomplete observations. We provide basic mathematical characteristics and important statistical functions of the Cauchy model under neutrosophic framework. A complete procedure of random numbers generation using neutrosophic quantile function is discussed. The unknown parameters of the proposed are estimated using the maximum likelihood approach. Numerical results show that the proposed model adequately fits the data involving extreme and imprecise values. The performance and flexibility of the model are also supported by an application to a real data set.
A Review of Research and Development on Lung Cancer Drugs
Authors: Ma Jun
Published: January 2025

With an incidence of 1.2 million new cases reported annually worldwide, 80% of which are non-small cell lung cancer, the majority of which are advanced at the time of diagnosis and have a poor prognosis, lung cancer continues to be the leading cause of cancer-related mortality in many countries. The effectiveness of chemotherapy for advanced lung cancer is still lacking, despite notable advancements in this area. The most prevalent histologic form of lung cancer is non-small cell lung cancer (NSCLC). Platinum-based chemotherapy is the conventional treatment for individuals with advanced non-small cell lung cancer (NSCLC), although it has a high rate of side effects and is not very effective. In recent years, molecular targeted therapy has become an important therapeutic tool for patients with advanced NSCLC with the continuous development of lung cancer targets and molecular targeted drugs. At present, these drugs have been successfully applied in the clinic and achieved remarkable efficacy, creating a new era of molecularly targeted therapy for NSCLC. The paper summarizes the progress of molecularly targeted therapy for advanced NSCLC. Targeted therapeutic drugs are now widely used in clinical practice and play an important role in tumor treatment, but most of them are resistant after a period of time. In addition, the high price limits their uses in general patients. Therefore, new drugs with lower efficacy, smaller side effects, a longer effective time, and a reasonable price are expected to come out as soon as possible