bluuebunny/crossref_metadata_2025 huggingface dataset:
N-acetilcisteína un fármaco multiuso: aplicación en trastornos psiquiátricos y enfermedades neurodegenerativas
Authors: Betancourth Sanmartín Kevin , Méndez Mendoza Karla Nicole , Domínguez Villizhanay Juan Diego , León Martínez Fernando Mauricio
Published: August 2024

Objetivo: Investigar el uso de NAC como tratamiento en trastornos psiquiátricos y enfermedades neurodegenerativas. Materiales y métodos: Análisis descriptivo de artículos en español, inglés y portugués publicados en los últimos 9 años, en base de datos como: Scopus, Web of Sciences, Science Direct, PubMed, SciELO, Elsevier y Redalyc. Se utilizan descriptores DECs, MeSH y operadores booleanos. Resultados: La NAC es eficaz como mucolítico, antídoto para intoxicaciones por paracetamol y coadyuvante en trastornos respiratorios. También muestra propiedades proneurogénicas y neuroprotectoras, reduciendo el estrés oxidativo e inflamación cerebral en diversas enfermedades como EP, EA, TOC y otras. Conclusiones: La NAC tiene potencial terapéutico en afecciones neurológicas y psiquiátricas; pero se requieren más estudios para comprender su efectividad y alcance completo.
Evaluación de la Investigación Educativa en Ciencias Médicas y de la Salud
Authors: León Pérez Ronny Sebastián , Leiva Suero Lizette Elena , Quishpe Jara Graciela de las Mercedes , Hernández Navarro Elena Vicenta , Proaño Alulema Ricardo Xavier , Chicaiza Quishpe Diana Cristina
Published: August 2024

Resumen:
Introducción: Precisar los criterios de evaluación de la investigación educativa es crucial para asegurar la calidad, la fiabilidad y la validez de los estudios realizados, garantizando su impacto en el perfeccionamiento curricular y el desarrollo académico científico e investigativo de instituciones de Educación Superior.
 Objetivo: Realizar una revisión sistemática de la literatura sobre los criterios de evaluación de la investigación educativa.
Metodología: Se realizó Revisión sistemática de laliteratura científica según metodología PRISMA sobre artículos publicados en revistas indexadas, durante el periodo 2014-2024, en bases de datos: Scopus, WOS, PubMed, ProQuest, Embase, Redalyc, Ovid, Medline, DynaMed y ClinicalKey. Se emplearon dos modelos para combinar estadísticamente los resultados: de efectos fijos y de efectos aleatorios
Resultados: La revisión sistemática aportó 25 artículos, excluidos 8 y elegidos 13, que permitieron evaluar los aspectos de esta revisión.
Conclusiones: Los criterios de evaluación de la investigación educativa enunciados permiten una valoración objetiva y sistemática de los métodos, resultados e impacto, garantizando la rigurosidad y reproductibilidad de las mismas, facilitando la comparación entre estudios, promoviendo la transparencia y la credibilidad en el ámbito académico y científico. Todo lo cual incide en la mejora continua de las prácticas educativas en el campo de las Ciencias Médicas y de la Salud, orientando las políticas y estrategias pedagógicas basadas en evidencia robusta y bien fundamentada que facilita el perfeccionamiento curricular.
Palabras Clave: Academias e Institutos, Educación Médica, Investigación educativa
Experiencia Docente en los Laboratorios de Simulación Médica
Authors: Martínez Pérez Sofía Carolina
Published: August 2024

En los últimos años la simulación médica no solo ha revolucionado la manera en que se enseñan las habilidades clínicas, sino que también ha mejorado la preparación y la confianza de los estudiantes antes de enfrentarse a situaciones reales y como docentes en esta área nos brinda la oportunidad de estar a la vanguardia de esta evolución educativa.
La formación en los laboratorios de simulación médica es una experiencia enriquecedora y a la vez desafiante para el docente universitario siendo uno de los aspectos más enriquecedores la capacidad de innovar en los métodos de enseñanza, teniendo como nuestro mejor aliado la tecnología que nos permite crear escenarios altamente realistas que replican situaciones clínicas complejas, además de ser bien aceptados por las nuevas generaciones de estudiantes,  donde el uso de nuevas tecnologías es parte del éxito en la educación actual, sin embargo esta experiencia no está exenta de desafíos pues la  preparación de escenarios detallados y realistas requiere una inversión significativa de tiempo, recursos y capacitaciones constantes para mantenerse actualizado con las últimas tecnologías y métodos educativos para garantizar que la enseñanza sea de la más alta calidad.
Actualizaciones en el manejo del shock cardiogénico, una revisión de la literatura
Authors: Robalino Rosero María José , Zumárraga Denys Patricio
Published: August 2024

El shock cardiogénico es una patología que se presenta típicamente posterior a un infarto agudo de miocardio, aunque existen más etiologías, el IAM es la causa más frecuente, esta entidad clínica sigue teniendo un alto grado de mortalidad debido a que el paciente puede progresar rápidamente, teniendo una muerte inminente, es por lo que se requiere analizar y estudiar más ampliamente el manejo y tratamiento. Objetivo: Describir cuales son las nuevas actualizaciones en el manejo del shock cardiogénico. Metodología: El presente artículo se trata de una revisión bibliográfica que se basó en 27 artículos científicos obtenidos por fuentes de información como: Pubmed, Google scholar, Clarivate web de la ciencia y Scopus. La estrategia de búsqueda se basó en la utilización de palabras clave como. IAM, ICC, shock cardiogénico, manejo, tratamiento y PIC. Se incluyeron aquellos estudios que cumplían con los criterios de inclusión, los cuales son:  haber sido escritos en español e inglés, publicados en los últimos cinco años (2019-2023), que aborden el tema de shock cardiogénico y que sean originales, de acceso completo y gratuito. Los criterios de exclusión que se establecieron son: artículos que hayan sido publicados previo al 2019, investigaciones que no se relacionen con el tema de estudio y que hayan sido escritos en otro idioma diferente a inglés y español. Resultados: El shock cardiogénico (SC) es más común en hombres de 61 años, causado principalmente por infarto agudo de miocardio (IAM). La hipertensión y la diabetes son comorbilidades frecuentes. La intervención coronaria percutánea y el uso de norepinefrina y dobutamina son esenciales. La mortalidad es del 43.9% a los 30 días. Discusión: Es difícil de establecer un tratamiento estándar para el SC, debido a sus múltiples causas y fenotipos. La identificación rápida y el manejo adecuado son cruciales. Conclusiones: El SC, frecuentemente causado por IAM, tiene alta mortalidad, especialmente en pacientes adultos mayores con hipertensión. Los avances en terapias y dispositivos han mejorado el tratamiento. La detección rápida y el manejo personalizado son esenciales para mejorar la supervivencia.
Sinostosis carpiana en paciente masculino de 52 años: reporte de caso
Authors: Nivelo Andrade Lenin Ángel , Nivelo Andrade Daysi Aracely , Játiva Serrano Laura Prisila
Published: August 2024

La sinostosis ósea es la fusión de algunos huesos adyacentes, pueden tener origen traumático o congénito, su diagnóstico es incidental y no hay necesitad de tratamiento quirúrgico, a menos que haya problemas del desarrollo normal con dolor.
Para este estudio se utilizó un equipo de Rayos X Digital Directo, en un paciente que aseguraba haber sufrido varias fracturas de muñeca pero que no habían sido revisadas ni tratadas pues no acudió al médico y no tenía estudios anteriores de las mismas, cabe recalcar que no tenía movilidad correcta en esta articulación.
Los hallazgos imagenológicos permitieron conocer que las características de la lesión pertenecían a una sinostosis o coalición carpiana congénita ya que no existían trazos de fracturas antiguas
योग र प्राकृतिक चिकित्सा
Authors: न्यौपाने Neupane दामोदर Damodar
Published: August 2024

उपनिषद्मा भनिएको छ— शरीरमाद्यं खलु धर्मसाधनम् अर्थात् पहिले शरीरको रक्षा गर्नु, त्यसपछि धर्मको साधना गर्नु । धर्म आर्जन गर्ने माध्यम शरीर हो । मानव जीवनमा शरीरको अपरीहार्यतालाई आत्मसात् गर्दै पतञ्जलि योगदर्शनका आठ अङ्गहरूको महत्त्व र तिनको दैनिक जीवनमा प्रयोगका बारेमा यस लेखमा वर्णन गरिएको छ । प्राकृतिक चिकित्साका विभिन्न आयामहरू विशेष गरेर दश आधारभूत सिद्धान्तहरूका बारे चर्चा गरिएको छ । योग दर्शनले मानव जीवनको उच्चतम उपलब्धि आत्मसाक्षात्कारको प्रयोगात्मक पक्षको बारेमा विश्लेषण गर्ने प्रयत्न गरिएको छ भने प्राकृतिक चिकित्सा विज्ञानको सन्दर्भमा औषधि मुक्त उपचार पद्धतिको बारेमा चर्चा गर्ने प्रयास गरिएको छ । योगाभ्यासले मानिसको शारीरिक तथा मानसिक अवस्थालाई मजबुत बनाई प्राकृतिक चिकित्साको प्रभावलाई समेत बढाउँछ ।
सामाजिक समावेशिताको एथ्नोग्राफिक आयाम
Authors: अर्याल Aryal रुद्र Rudra
Published: August 2024

एथ्नोग्राफिक अध्ययनमा आधारित यो लेखले नेपालको सुदुरपश्चिमको पहाडी क्षेत्रमा रहेको एउटा उदाउँदो नगर र त्यस आसापासको ग्रामिण भेगहरूमा समावेशिता र असमावेशीका विविध आयाम र चरित्र बाहिर ल्याएको छ । हालका स्थानीय तहका सरकारले सामाजिक समावेशिताका विषयमा के कसरी चासो, चिन्ता राख्दै आफ्ना अधिकारहरूलाई उपयोगमा ल्याउन कत्तिको सफल छन् वा छैनन् भन्ने विषयमा यो लेखले प्रष्ट पारेको छ । जसरी असमावेशीकरणका विविध आयामहरू स्थानीय माताहतका समाज, समुदाय र सरकारहरूले भत्काउन सकेका छैनन् । त्यसैगरी समावेशीकरणको अभियान र अभ्यासले यथोचित स्थान पाउन नसकेको यो लेखले स्वीकार गरेको छ । यसका साथै साङ्गठनिक परिपाटी बोकेका स्थानीय घरपरिवार, गाउँटोल, संस्थासमूह, आदिको देखिने र लुप्त किसिमको असमावेशी चरित्रलाई प्राथमिकतामा राखी तिनलाई समावेशीको अवरोधकका रूपमा विश्लेषण गरिएको छ । गुणात्मक अनुसन्धान विधिमा आधारित रही सूचना र जानकारी सङ्कलनका लागि स्थलगत क्षेत्रको अवलोकन, विभिन्न व्यक्तिहरूसँगको औपचारीक र अनौपचारिक अन्तरवार्ता तथा कुराकानीहरू, छलफल, आदिको सहयोग लिइएको छ ।
चिताको ज्वाला कथामा रस
Authors: कार्की बेनुबहादुर
Published: August 2024

प्रस्तुत अनुसन्धानात्मक लेखमा कथाकार गुरुप्रसाद मैनालीको चिताको ज्वाला कथामा प्रयोग गरिएको रससिद्धान्तका कोणबाट विश्लेषण र मूल्याङ्कन भएको छ । यो लेख गुणात्मक अनुसन्धानमा आधारितपाठमा रहेका उद्धरणको विश्लेषणका आधारमा तयार भएको छ । यस लेखको सैद्धान्तिक आधार रस सिद्धान्त हो । यस कथामा अङ्गी रसका रुपमा शोक स्थायी भावको प्रकटीकरण हुने करुण रसको उपस्थिति छ भने यसलाई परिपाकावस्थामा पु¥याउनका लागि अन्य रसको प्रयोग भएको छ । यस कथामा अङ्ग रसका रुपमा श्रृङ्गार रस प्रयोग भएको छ भने अन्य रसमा भयानक रस, वीभत्सरस शान्त रस, र अद्भूत रसको प्रयोग भएको छ । यस लेखमा अङ्गी रसका रुपमा करुण रसको विश्लेषणका साथै यसमा आएका अन्य रसका विषयमा विमर्श भएको छ ।
इन्द्र बहादुर राईका कथामा परम्परावादी र प्रयोगवादी प्रवृत्ति
Authors: शर्मा Sharma उर्मिला Urmila
Published: August 2024

इन्द्रबहादुर राई नेपाली भाषा, संस्कृति, जाति र साहित्यप्रति असीम आस्था र विश्वास राख्ने बहुमुखी स्रष्टा हुन् । यिनको साहित्यसिर्जनले विशेष गरी नेपाली समालोचना र आख्यानका क्षेत्रमा नवीनता, प्रयोगशीलता र बौद्धिकताको प्रवेश र विस्तार भएको छ । प्रयोगवादी उपन्यासकार राई परम्परावादी र प्रयोगवादी कथाकार पनि हुन् । परम्परावादी कथाकारको रूपमा राईले प्रवासी नेपाली जीवनलाई यथार्थवादी र मनोवैज्ञानिक ढङ्गमा आफ्ना कथामा अभिव्यञ्जित गरेका छन् भने प्रयोगवादी कथाकारका रूपमा सिद्धान्ततः यिनी आयामिक र लीलालेखनका कथाकार हुन् । पश्चिमी चिन्तन र आख्यानलेखनलाई नेपाली कथापरम्परामा समाहित गर्न सक्षम राईले कथाको सिद्धान्त र प्रयोगलाई जीवनजस्तै प्रयोगशील र गतिशील बनाएका छन् । यस आलेखमा राईका कथामा पाइने परम्परावादी र प्रयोगवादी कथाप्रवृत्तिहरूको विश्लेषण गरिएको छ । यस किसिमको तुलनात्मक विश्लेषणबाट परम्परावादी र प्रयोगवादी दुवै किसिमका प्रवृत्तिलाई कथामा सशक्त रूपमा प्रस्तुत गर्न सक्नु कथाकार राईको उल्लेख्य वैशिष्ट्य हो भन्ने निचोड प्राप्त भएको छ ।
आफर कवितासङ्ग्रहमा दलित चेतना
Authors: श्रेष्ठ Shrestha चन्द्रमान  Chandraman
Published: August 2024

प्रस्तुत शोधलेखमा उन्मुक्त पुस्ताद्वारा लेखिएको ‘आफर’ कवितासङ्ग्रहको दलित चेतनाका आधारमा अध्ययन गरिएको छ । सामाजिक, सांस्कृतिक र आर्थिक दृष्टिले उत्पीडनमा पारिएका जातिहरूको समुदाय नै दलित हुन् । मनुवादी हिन्दू वर्णव्यवस्थामा आधारित नेपाली समाजमा दलित समुदायले लामो समयदेखि शोषण र उत्पीडन भोग्दै आएका छन् । दलित मुक्तिका लागि सर्वप्रथम भारतका भीमराव अम्बेडकरले सङ्गठित रूपमा आवाज उठाउने काम गरे । तिनै दलितका समस्यालाई प्रस्तुत गर्दै दलितमुक्तिको आह्वान गरिएको साहित्य नै दलित साहित्य हो । हिन्दू वर्णव्यवस्थाको विरोध, सामाजिक तथा सांस्कृतिक उत्पीडनको विरोध, स्वतन्त्रता, समानता र बन्धुत्वको भावना, श्रम शोषणको विरोध, दलित नायकत्वको स्थापना आदि दलित साहित्यका आधारभूत मान्यता हुन् । यस लेखमा दलित साहित्यसम्बन्धी यिनै मुख्य मान्यताहरूलाई आधार बनाएर ‘आफर’ कवितासङ्ग्रहको अध्ययन गर्ने काम गरिएको छ । अध्ययनका क्रममा ‘आफर’ भित्रका कविताहरूले दलितको समस्यालाई सघन रूपमा उठाउँदै उनीहरूको सामाजिक मूल्य स्थापित हुनुपर्दछ भन्ने मुक्तिको आवाजलाई प्रखर रूपमा प्रस्तुत गरेको निष्कर्ष निकालिएको छ ।
ACIDENTES PROVOCADOS POR CNIDÁRIOS NAS PRAIAS DE SÃO LUÍS - MA
Authors: Santos Diniz Thalline , Moreno Silva Lima Mauricio Emanuel , Lopes de Lima Kaio , Magalhães Silva Camila
Published: August 2024

As praias apresentam condições ambientais favoráveis para acidentes causados por organismos aquáticos. Este trabalho objetivou analisar as ocorrências de acidentes causados por animais marinhos nas praias de São Marcos e Calhau do município de São Luís-MA no período 2017 a 2021. Foram realizados levantamento de dados pretéritos nos órgãos competentes referente à ocorrência e frequência de acidentes por praia, período do ano de maior ocorrência, principais espécies causadoras, sintomas clínicos, medidas de primeiro socorro e medidas de precaução. Os resultados mostram, a ocorrência de 271 acidentes causados principalmente por caravela-portuguesa e água viva na Praia do Calhau, no mês de julho e nos meses de setembro a dezembro. As vítimas apresentaram os sintomas clínicos como: irritação, ardência, vermelhidão e marcas dolorosas. Estas foram submetidas às medidas de primeiros-socorros como aplicação de vinagre e/ou água do mar.  As medidas de precaução basearam-se da abordagem diária e campanha e orientação sobre os riscos. Neste contexto, percebe-se que os acidentes ocorridos nas praias ludovicenses causam transtornos aos frequentadores destas, ocasionando insegurança para banhistas. Além disso, provocam danos econômicos para a saúde pública e o turismo.
CHARACTERIZATION OF ENVIRONMENTAL INEQUALITIES AMONG A MINING TOWN'S NEIGHBORHOODS CASE STUDY: OUENZA – EAST OF ALGERIA
Authors: Berrahail Guendouze  , Soufiane Sid Ahmed  , Brahim Djebnoune
Published: August 2024

The waste resulting from mining can contaminate waterways or seep into soils and seriously pollute the environment; therefore it can impact the health of residents. However, these impacts are often deemed differently by this population. This difference is commonly called: "Environmental inequalities". This article spots the light on characterizing environmental inequalities in the mining town: Ouenza, which is located in the extreme east of Algeria. Through a questionnaire conducted in five areas of the town and using sphinx software to analyze results by CFA, we attempted to identify the impact of the extraction activity in this town and to determine the inequalities among the different zones and the factors behind them such as the proximity or the direction of wind.
The state, structural and dynamic trends and prospects for increasing profitability of agriculture in Russia
Authors:   Kabardino-Balkarian State Agrarian University, Nalchik, Russia, Rakhaev Khadis M. , Duguzheva Natella M ,   Kabardino-Balkarian State Agrarian University, Nalchik, Russia, Sarbasheva Elena M. ,   Kabardino-Balkarian State Agrarian University, Nalchik, Russia, Toguzaev Takhir Kh. ,   Kabardino-Balkarian State Agrarian University, Nalchik, Russia, Gazaeva Madina Sh. ,   Kabardino-Balkarian State Agrarian University, Nalchik, Russia
Published: August 2024

Profitability is the most important indicator of the financial condition of economic activity in terms of market relations. It expresses the degree of market performance and efficiency of enterprises, organizations, industries and products. Being a kind of synthetic indicator of performance, profitability depends on many factors of both production and market nature. Therefore, it becomes an important task not only to identify the factors influencing the level of profitability, their quantification and justification, but also to develop forecasts and measures to increase the level of profitability. All this involves statistical analysis, identification of the main structural and dynamic trends and the development of a set of measures to improve and sustain the level of profitability in the industry.
Current trends in demographic processes in rural areas of the Russian Federation
Authors:   VNIOPTUSKH is a branch of the Federal Scientific Center for Agrarian Economics and Social Development of Rural Areas – VNIIESH, Moscow, Russia, Afanasyev Valery I.
Published: August 2024

The latest demographic forecast of the population of the Russian Federation for the period up to 2046, conducted by Rosstat, reflects a negative trend, and rural areas are not an exception in it. In this situation, the relevance of research on demographic processes in rural areas is increasing. The article provides an analysis of statistical data on population dynamics, indicators of natural movement of rural and urban populations, which made it possible to identify the most difficult problems that have a negative impact on the demographic situation in rural areas. The author gives an assessment of the measures being implemented and necessary for the implementation of effective socio-economic development of rural areas, accompanied by an increase in the number of rural population and the quality of their lives.
Weather and climate conditions and food prices in the 1st quarter of 2024 in Russia and abroad
Authors:   VIAPI named after A.A. Nikonov is a branch of the Federal Scientific Center for Agrarian Economics and Social Development of Rural Areas– VNIIESH, Moscow, Russia, Sobolev Oleg S.
Published: August 2024

The article notes the weather and climatic conditions of agricultural production in the regions of the European part of the Russian Federation. They were characterized by heavy snowfalls, high levels of snow cover and low temperatures in January in the 1st quarter. A comparison of producer prices for grain, milk and meat on the food markets of Russia, the EU and the USA is provided. There was an increase in domestic sugar prices in the 1st quarter. Recommendations are given to curb domestic sugar inflation and inflation of domestic tomatoes.
GESTÃO DO CLIMA ORGANIZACIONAL E A EFICIÊNCIA DO HOME OFFICE
Authors: Loureiro Adeylson Felix
Published: August 2024

Este estudo visa explorar a correlação entre a gestão do clima organizacional e a eficiência do home office, um fenômeno significativamente ampliado em 2020 devido à pandemia de COVID-19. A ascensão do trabalho remoto levantou questionamentos sobre sua eficácia, especialmente no que diz respeito à produtividade e satisfação dos colaboradores. Adotando uma abordagem baseada em revisão sistemática da literatura, o objetivo principal é compreender como a gestão do clima organizacional influencia as dinâmicas organizacionais, coesão da equipe e experiência do colaborador no contexto do home office. Os resultados destacam que essa modalidade de trabalho apresenta oportunidades e desafios, tornando crucial a gestão do clima organizacional. A análise revela que estratégias específicas, como a promoção da comunicação, o estabelecimento de espaços de trabalho adequados e o suporte contínuo aos colaboradores, são essenciais para otimizar a eficiência do home office. Academicamente, este estudo contribui para o entendimento mais amplo das dinâmicas organizacionais contemporâneas, oferecendo insights valiosos para pesquisadores interessados na correlação entre gestão do clima e trabalho remoto. Do ponto de vista prático, fornece orientações essenciais para empresas e profissionais, destacando a importância da gestão do clima organizacional para promover ambientes de trabalho remoto eficientes e sustentáveis. Essas descobertas contribuem para práticas organizacionais mais adaptáveis e centradas no colaborador, facilitando a transição para modelos de trabalho flexíveis e inovadores.
Sistem Pakar Mengantisipasi Permasalahan Tanaman Jagung Manis Menggunakan Metode Certainty Factor Dan Dempster-Shafer
Authors: Nur Hasanah Pohan  , Ilka zufria  , Suhardi
Published: August 2024

Jagung manis (Zea mays L.) merupakan satu jenis tanaman utama dalam industri pangan dan pertanian. Namun, petani sering menghadapi kendala dalam mengidentifikasi dan mengatasi hama serta penyakit yang menyerang tanaman jagung manis. Penelitian dilakukan dengan tujuan menyelesaikan masalah dengan mengembangkan sistem pakar yang memanfaatkan metode Certainty Factor dan Dempster-Shafer. Temuan menunjukkan bahwa penggabungan metode ini meningkatkan ketepatan diagnosis terhadap hama dan penyakit yang biasa menyerang tanaman jagung manis. Sistem pakar yang dibangun berbasis web bertujuan untuk memberikan bantuan kepada petani dalam mengidentifikasi dan menyelesaikan hama dan penyakit pada tanaman jagung manis. Hasil penelitian mengungkapkan bahwa hama merupakan masalah utama dengan tingkat kejadian tertinggi mencapai 67%. Diharapkan penelitian ini dapat memberikan kontribusi signifikan bagi petani dalam meningkatkan hasil panen mereka serta memberikan informasi yang berharga bagi lembaga pertanian.
Pojęcie oraz typy dóbr osobistych w świetle prawa polskiego
Authors: Bieranowski Jakub
Published: August 2024

Dobra osobiste to wartości o charakterze niemajątkowym, mające szczególne znaczenie dla poszanowania godności i czci każdego człowieka, oddające jego przynależność psychiczną i fizyczną względem nich. Celem artykułu jest przedstawienie pojęcia oraz typów dóbr osobistych, które są uregulowane w Kodeksie cywilnym, Konstytucji RP oraz w ustawie o prawach autorskich i pokrewnych, a także w oparciu o praktykę sądową. Praca przedstawia dobra osobiste, takie jak: życie, zdrowie, nietykalność cielesną oraz integralność seksualną, wolność i swobodę sumienia, które dają możliwość zachowań zgodnych z wolą człowieka, wyrażania swoich poglądów oraz wyznawania religii. Kolejnym typem dóbr osobistych jest cześć, dobre imię i godność osobista, a także wizerunek, którego bez zgody nie można rozpowszechniać oraz nazwisko i pseudonim, stanowiące identyfikację jednostki. Praca prezentuje również inne dobra, takie jak tajemnica korespondencji czy nietykalność mieszkania. Wskazane dobra, uregulowane przez prawo, stanowią nieodzowne uprawnienia życia człowieka, a także przejawiają się w życiu codziennym oraz cechują się największą doniosłością w kontekście prawa do prywatności, dlatego zasługują one na szczególną uwagę.
The Monro-Kellie doctrine in its own context
Authors: Picard Nelson A.
Published: August 2024

In 1783, Alexander Monro secundus maintained that because the brain is enclosed in a case of bone and its substance is nearly incompressible, the quantity of blood within the head must be the same, or very nearly the same, at all times. Years later, this hypothesis was experimentally supported by George Kellie, and became known as the Monro-Kellie doctrine. However, this doctrine encountered resistance. Its reviewers have agreed to point out the historically understandable error of not having considered the CSF as a normal intracranial volume. Yet, almost nothing has been published about some of the physiological, pathophysiological, and therapeutic ideas prevailing at that time that may have influenced Monro’s hypothesis. Lastly, and perhaps most importantly, it is not clear why Monro, who knew the ventricular system in detail, did not include it as a potential compensatory compartment for changes in the intracranial blood volume.
Lateral compartment of the cavernous sinus from the endoscopic endonasal approach: anatomical considerations and surgical relevance to adenoma surgery
Authors: Xu Yuanzhi , Asmaro Karam , Lee Christine K. , Vigo Vera , Mohyeldin Ahmed , Nunez Maximiliano Alberto , Cohen-Gadol Aaron A. , Fernandez-Miranda Juan C.
Published: August 2024

OBJECTIVE

The cavernous sinus (CS) has 4 compartments: superior, inferior, posterior, and lateral. Among these, the lateral compartment is the most common location for residual tumor, given the risk of neurovascular injury. The authors’ study aimed to delineate the anatomical landmarks in this area and illustrate the technical nuances of the lateral transcavernous approach.

METHODS

Twenty-two colored silicone–injected specimens were dissected via an endoscopic endonasal approach to the lateral compartment of the CS. The anatomical landmarks and the internal carotid artery (ICA) mobilization technique were investigated. Two illustrative cases are provided.

RESULTS

The lateral compartment of the CS is bounded by the carotid-oculomotor membrane (COM) and optic strut as the roof and the petrolingual ligament and lingual process as the floor. It is divided into 2 asymmetrical subcompartments: the upper, larger subcompartment, located superior to the abducens nerve, accommodates the lateral parasellar ligament (LPL), inferolateral trunk (ILT), and branches of the tentorial artery; and the lower, smaller subcompartment, inferior to the abducens nerve, accommodates only the sympathetic nerve branches as they join the abducens nerve. The LPL is a well-defined ligamentous band and was identified in 38 (86%) hemispheres with 2 distinct configurations: 1) robust LPL (59%), with highly compacted ligamentous bands tightly adherent to the ICA; and 2) dispersed LPL (27%), with less compaction and adherence to ICA. The main attachment of the LPL to the cavernous ICA was most commonly observed at the horizontal ICA segment (55%), followed by the anterior (18%) and posterior (14%) genua. The ILT, as the main vessel in the lateral compartment, was identified in 41 (93%) hemispheres and originated from the horizontal ICA segment (80%) or the anterior genu (14%), from either the lateral (52%) or inferior (41%) aspect of the cross-section of the ICA. In 64% of hemispheres, the LPL wrapped the ILT, abducens nerve, and sympathetic nerve to form a broad and firm neurovascular-ligamental complex. Transection of the LPL, ILT, and COM enables medial ICA mobilization and enhances access to the lateral compartment of the CS, potentially increasing the exposure width by 6 ± 1 mm.

CONCLUSIONS

This study provides valuable insights into the anatomical intricacies of the lateral compartment of the CS and underscores the potential benefits of the endoscopic endonasal lateral transcavernous approach. Further clinical applications are essential for validating these findings and optimizing surgical outcomes.
Pipeline embolization device placement under local versus general anesthesia: a propensity score–matched study
Authors: Zhang Longhui , Wang Chao , Wu Xuefang , Wu Xinzhi , Zhang Yisen , Liu Jian , Jia Baixue , Zhu Haoyu , Miao Zhongrong , Chen Fangguang , Wang Yun , Jiao Qinggui , Zhang Ying , Lv Ming
Published: August 2024

OBJECTIVE

Pipeline embolization device (PED) placement for the treatment of intracranial aneurysms is safe and effective under general anesthesia (GA). However, GA is associated with certain risks, longer procedural time, and higher hospital cost. The authors aimed to compare clinical outcomes and hospital cost between GA and local anesthesia (LA) procedures in patients who underwent PED placement for intracranial aneurysm treatment.

METHODS

This retrospective study analyzed the charts of 216 patients with 223 intracranial aneurysms treated using the PED from June 2022 to March 2023. Cases were grouped according to type of anesthesia administered (LA or GA). Propensity score matching (PSM) was used to balance the groups to minimize confounding bias.

RESULTS

Eighty-four patients with 88 aneurysms were treated under LA, and 132 patients with 135 aneurysms were treated under GA. The complication rate and modified Rankin Scale score at 6 months were similar in both groups. Procedural time was significantly shorter with LA both before (87.47 ± 22.68 minutes vs 118.90 ± 46.80 minutes, p < 0.001) and after (84.75 ± 16.77 minutes vs 110.02 ± 38.56 minutes, p < 0.001) PSM. LA eliminates the need for postanesthesia recovery. Hospital cost was significantly lower in the LA group both before ($30,820.74 ± $3216.93 vs $32,846.62 ± $4731.50, p = 0.001) and after ($30,127.83 ± $2763.12 vs $33,874.41 ± $3163.56, p = 0.002) PSM.

CONCLUSIONS

PED placement under LA can achieve satisfactory outcomes similar to those of PED placement under GA; however, the use of LA reduces procedural time and hospital cost.
Sublabial transmaxillary approach to the inferior aspect of the orbit
Authors: Doğruel Yücel , Güngör Abuzer , Türe Hatice , Türe Uğur
Published: August 2024

OBJECTIVE

The objective was to demonstrate the surgical steps and outcomes of the sublabial transmaxillary microsurgical approach with endoscopic assistance to treat lesions in the inferior aspect of the orbit, as well as to describe the use of patient-specific 3D models to facilitate surgical preparation and improve experience with the technique.

METHODS

The authors’ study evaluated data from patients who underwent an endoscope-assisted sublabial transmaxillary approach for inferior orbital lesions. For 2 patients, 3D models were created for preoperative planning and assessment of the approach. Surgical steps comprised osteotomy to access the maxillary sinus, bony resection of the orbital floor, opening of the periorbital fascia, and dissecting and removing the lesion, followed by closure. The neuroendoscope was used to inspect the surgical cavity between each step.

RESULTS

The study included 5 patients with varying visual field defects and proptosis who underwent the sublabial transmaxillary microsurgical approach with endoscopic assistance. Complete resection was achieved in all, and all patients reported improvement in visual field defects and proptosis after the procedure. No complications were observed except for transient unilateral maxillary edema noted around the incision site in 3 patients during the early postoperative period, which resolved within a few days. Histopathological examination confirmed the diagnosis of cavernous malformation in all patients.

CONCLUSIONS

The sublabial transmaxillary approach is a direct and safe method to resect cavernous malformations at the inferior aspect of the orbit. It reduces the risk of complications associated with lateral, transcranial, and transnasal approaches that may cross critical structures. The microsurgical approach provides the benefit of two-handed dissection for lesions embedded in orbital fat, which can be challenging because of adhesions to surrounding tissues. The use of 3D models can facilitate surgical planning and enhance familiarity with the approach.
Velocity and pattern of growth of intracranial meningiomas
Authors: Häni Levin , Thomann Pascal , Maragkou Theoni , Vulcu Sonja , Schütz Alessa , Jesse Christopher Marvin , Söll Nicole , Hakim Arsany , Raabe Andreas , Schucht Philippe
Published: August 2024

OBJECTIVE

The authors’ aim was to assess the velocity and pattern of growth of meningiomas and to correlate the kinetics of tumor growth with their previously reported two-item radiological risk stratification and CNS WHO grade (5th edition, 2021).

METHODS

The authors performed a serial volumetric analysis of meningiomas diagnosed radiologically at their institution between 2003 and 2015. The primary endpoint was velocity of diametric expansion (VDE), which represents the slope of the linear regression of the mean tumor diameter against time. For the secondary analysis, they categorized the growth patterns as linear or exponential by fitting time-volume curves to a linear and exponential function. Three radiological risk categories based on T2-weighted iso/hyperintensity and absence of calcifications were compared: low risk (T2-weighted hypointense), intermediate-risk (T2-weighted iso/hyperintense with calcifications), and high-risk (T2-weighted iso/hyperintense without calcifications) tumors.

RESULTS

For the entire cohort of 240 meningiomas, the median (IQR) VDE was 0.33 (0.00–0.71) mm/year. Distribution of VDE differed significantly among radiological risk categories (0.49 vs 0.35 vs 0.05 mm/year, p < 0.001). High-risk and intermediate-risk tumors more frequently tended to grow exponentially compared to low-risk tumors (43.8% vs 37.0% vs 8.3%, p = 0.067). The authors found no correlation of growth velocity with CNS WHO grade in their cohort (1.30 mm/year for CNS WHO grade 1 vs 4.01 mm/year for CNS WHO grade 2, p = 0.185).

CONCLUSIONS

A radiological risk assessment using two parameters—T2-weighted signal iso/hyperintensity and absence of calcifications—allows estimation of growth velocity and characteristics of untreated intracranial meningiomas. Only high-risk tumors exhibit the potential for rapid growth. However, rapid tumor growth does not indicate a higher CNS WHO grade per se.
Intracranial ependymomas in pediatric patients: patterns of care, disparities, and survival outcomes from the National Cancer Database
Authors: Jagtiani Pemla , Karabacak Mert , Le Chi , Bahadir Zeynep , Morgenstern Peter F. , Margetis Konstantinos
Published: August 2024

OBJECTIVE

This study aimed to extract and analyze comprehensive data from the National Cancer Database (NCDB) to gain insights into the epidemiological prevalence, treatment patterns, and survival outcomes associated with intracranial ependymomas in pediatric patients.

METHODS

The authors examined data extracted from the NCDB spanning the years 2010 to 2017, with a specific emphasis on intracranial ependymomas in individuals aged 0–21 years. The study used logistic and Poisson regression, along with Kaplan-Meier survival estimates and Cox proportional hazards models, for analysis.

RESULTS

Among 908 included pediatric patients, 495 (54.5%) were male, and 702 (80.6%) were White. Kaplan-Meier analysis determined overall survival (OS) rates of 97.1% (95% CI 96%–98.2%) at 1 year postdiagnosis, 89% (95% CI 86.9%–91.1%) at 3 years, 82.9% (95% CI 80.3%–85.7%) at 5 years, and 74.5% (95% CI 69.8%–79.4%) at 10 years. Grade 3 tumors predicted a more than fourfold higher mortality hazard (p < 0.001; reference = grade 2). Infratentorial localization was also associated with a 1.7-fold increase in mortality hazard (p = 0.002; reference = supratentorial). Larger maximum tumor size (> 5 cm) correlated with a lower mortality hazard (HR 0.64, p = 0.011; reference ≤ 5 cm). The vast majority of patients (85.9%, n = 780) underwent resection. Uninsured patients had over fourfold higher prolonged length of stay (LOS) odds than those privately insured (OR 4.645, p = 0.007). Radiotherapy was received by 76.1% of patients, and the highest rates of radiotherapy occurred among children aged 5–12 years (p < 0.001). Only 25.6% received chemotherapy at any point during their treatment. Peak chemotherapy use emerged within ages 0–4 years, reaching 33.6% in this age group. Kaplan-Meier analysis indicated chemotherapy was associated with significantly worse OS (p = 0.041).

CONCLUSIONS

This comprehensive analysis of the NCDB provides valuable insights into the epidemiology, treatment patterns, and survival outcomes of intracranial ependymomas in pediatric patients. Higher tumor grade, infratentorial localization, and chemotherapy use was associated with worse OS, while larger tumor size correlated with lower mortality hazard. Disparities in care were identified, with uninsured patients experiencing prolonged LOS. These findings underscore the need for tailored treatment strategies based on patient and tumor characteristics and highlight the importance of addressing socioeconomic barriers to optimize outcomes for children with ependymomas.
Minimally invasive posterior cervical foraminotomy versus the anterior transcorporeal approach for cervical radiculopathy: a systematic review and meta-analysis
Authors: Rajjoub Rami , Nguyen Ryan , Ghaith Abdul Karim , El-Hajj Victor Gabriel , De Biase Gaetano , Onyedimma Chiduziem , Yolcu Yagiz U. , Jarrah Ryan , Elmi-Terander Adrian , Akinduro Oluwaseun O. , Abode-Iyamah Kingsley , Bydon Mohamad
Published: August 2024

OBJECTIVE

Surgical decompression is often indicated for symptomatic cases of cervical radiculopathy. In the cervical spine, minimally invasive posterior cervical foraminotomy (MIS-PCF) and the anterior transcorporeal approach (ATCA) are modern techniques available to surgeons. This systematic review and single-arm meta-analysis aimed to assess surgical and patient-reported outcomes of MIS-PCF and ATCA for cervical radiculopathy.

METHODS

A systematic review of the literature was conducted using 1) Ovid; 2) Epub Ahead of Print and In-Process, In-Data-Review & Other Non-Indexed Citations; and 3) Scopus databases, which reported outcomes following cervical decompression using MIS-PCF or the ATCA. Specifically, baseline characteristics, operative outcomes, and changes in visual analog scale (VAS) neck pain score were assessed. The quality of the studies was graded using the modified Newcastle-Ottawa Scale for observational studies.

RESULTS

Forty studies with 1661 patients were identified. The comparative analysis of both techniques revealed no significant differences in complication (7%, 95% CI 5%–10%, p = 0.75) or reoperation rates (5%, 95% CI 3%–7%, p = 0.41). Additionally, there were no significant differences in estimated blood loss (55.39, 95% CI 44.62–66.16 ml, p = 0.55) or operative time (85.15, 95% CI 65.38–104.92 minutes, p = 0.05). The ATCA showed significantly greater improvement (p < 0.01) in VAS neck pain scores following surgery (ATCA point reduction 6.7, 95% CI 6.0–7.5 points vs MIS-PCF 3.0, 95% CI 1.0–5.0 points).

CONCLUSIONS

The ATCA and MIS-PCF are effective modern techniques for the surgical treatment of radiculopathy. Both approaches showed comparable postoperative outcomes, including complication and reoperation rates. However, the ATCA was shown to provide significantly greater improvement in VAS neck pain scores.
360-degree Image Processing on NVIDIA Jetson Nano
Authors: Satyawan Arief Suryadi , Utomo Prio Adjie , Puspita Heni , Wulandari Ike Yuni
Published: August 2024

A wide field of vision is required for autonomous electric vehicles to operate object-detecting systems. By identifying objects, it is possible to imbue the car with human intelligence, similar to that of a driver, so that it can recognize items and make decisions to prevent collisions with them. Using a 360-degree camera is a wonderful idea because it can record events surrounding the car in a single shot. Nevertheless, 360º cameras produce naturally skewed images. To make the image appear normal but have a bigger capture area, it is required to normalize it. In this study, NVIDIA Jetson Nano is used to construct software for 360-degree image normalization processing using Python. To process an image in real-time, first choose the image shape mapping that can give information about the entire item that the camera collected. Then, choose and apply the mapping. Using Python on an NVIDIA Jetson Nano, the author of this research has successfully processed 360-degree images for local and real-time video as well as image geometry modifications.
Innovative Learning Media for Interior Design using Augmented Reality at Vocational High Schools
Authors: Sahria Yoga , Santoso Budi , Kuat Tri
Published: August 2024

One aspect of the concept of building design development is interior design. The accuracy of the placement of interior materials is very important for (SMK) students majoring in Building Drawing Engineering. However, it may be difficult to present and organize material in real life. This barrier can be caused by a lack of materials or the ability to see objects from multiple angles. To realize the Vocational Center of Excellence and SMK Bisa programs, augmented reality technology is present as a solution in vocational education. Augmented reality is a technology that allows virtual things to be placed in the real world. The reason for choosing this research topic is that users can interact with virtual things in an augmented reality environment providing them with hands-on experiences. Objects that are displayed in the form of interior materials can be in 3D so that they look as close as possible to the original object. Users can interact and change the location of interior materials directly and realistically using augmented reality applications. The method used in this research is the Lee & Owens Development Model starting from Assessment/analysis, Need assessment, front-end analysis, design, development, Implementation, and Evaluation. The application developed only includes some interior design materials, Design markers have a high level of augmentability, so users will be able to immediately see a 3D model when the marker is scanned, The application has been tested on several smartphones and the results are successful
Simulation and Analysis of Network Security using Port Knocking and Intrusion Prevention System on Linux Server
Authors: Parenreng Jumadi Mabe , Rizal Fahru , Wahyuni Maya Sari
Published: August 2024

This research aims to design and simulate a network security system using port knocking and an intrusion prevention system (IPS) on a Linux-based server and analyze its security using port scanning, brute force, and DoS attacks. IPS uses inline snort mode with DAQ NFQ. The test results show that port knocking successfully opens and closes the port according to the knock sequence so that only those who know the knock sequence can access the port. The port scanning, SSH, and FTP Brute Force test results were successfully detected by IPS so that the attacker could not obtain any information. DoS testing with LOIC increased server CPU and memory usage, but after IPS rules were applied, usage stabilized. DoS testing with slowhttptest makes the webserver inaccessible to users, but after the IPS rule is applied, web access runs normally. In conclusion, IPS was successful in preventing all attacks because the attack packets complied with IPS rules so they were detected as threats and dropped by IPS. Test results of the Telegram monitoring system show that the system succeeded in sending real-time attack notifications with an average time difference of 2.9 seconds, and the report, start, and stop features worked as expected.
Integration of Telkom ISP and 3 LTE Using PCC Method to Improve Internet Connection Stability
Authors: Putra Muh. Fardika Irwan Pratama , Parenreng Jumadi Mabe , Yahya Muhammad
Published: August 2024

This research focuses on improving internet connection stability at the Network Laboratory of JTIK, Faculty of Engineering, Universitas Negeri Makassar. The study aims to address the challenges of disruptions and instability frequently faced by users of Telkom WiFi in the laboratory, causing significant disruptions in internet activities. This instability is exacerbated by simultaneous internet usage, leading to network overload and bandwidth competition among users, ultimately reducing the overall network performance. As a solution, the research proposes the implementation of a network system that integrates Telkom ISP and 3 LTE using the PCC method. The system is equipped with a failover mechanism that automatically redirects the network connection to the active ISP when issues are detected. Additionally, the research categorizes users into admin lecturers and students, imposing bandwidth limitations specifically for students to prevent excessive network traffic. Three in-depth testing scenarios were conducted, demonstrating that the system smoothly redirects internet connections to the active ISP during issues, ensuring uninterrupted and effective internet access for users.
Hybrid Electrical Interchange System in IoT-Based Egg-Hatching Equipment
Authors: Parenreng Jumadi Mabe , Wahyuni Maya Sari , Lia Resky Amalia , Muliadi Muliadi , Adiba Fhatiah
Published: August 2024

Manual egg hatching still requires time and human labor every day to regulate temperature, adjust humidity, and turn the eggs. This egg hatcher works using solar panels as an alternative energy source. This study aims to design and determine the results of the effectiveness of testing the hybrid electrical interchange system on IoT-based egg hatchers. The research method used is the R&D method. Based on the results of the research, switching energy sources is declared valid because the tools and applications are integrated. The average voltage difference in the battery in charging condition by turning on the tool is -0.01 Volts, proving that even though it is in charging condition when the tool is turned on, the voltage in the battery will still decrease. The measurement results of the average daily energy demand on the hatchery by applying a hybrid electrical interchange system is 0.142 kWh and without applying the system 0.163 kWh, proving by applying a hybrid electrical interchange system device more efficient use of PLN electricity due to assistance from PLTS. On-off automation of lights and fans can keep the temperature at an ideal state of 37°C-39°C, thus affecting the egg-hatching process. On-off automation using a relay connected to a mist maker also affects keeping humidity at 55%-65% humidity, humidity also affects the egg-hatching process, where the success rate in hatching eggs is maximized. Based on the results of tests carried out by the hybrid electrical interchange system on IoT-based egg hatchers, it can be concluded that this tool can maintain the stability of temperature and humidity automatically in egg hatchers well until the eggs hatch.
Decision Support System for Selecting a Bus Company Using the SMART Method: A Case Study at Nuansa Utama Tour and Travel
Authors: Febriansyah Muhammad Adam , Latipah Latipah , Damastuti Natalia , Junaedi Lukman
Published: August 2024

The rapid development of bus transportation has a significant impact on the selection of bus companies, especially travel services. Nuansa Utama Tour, a travel service agency, still uses conventional methods in selecting a Bus Company, requiring more time and process. Each Bus Company has its characteristics, so it requires a decision-weighing method that is easy to understand. This research aims to build a system that helps travel owners choose Bus Company recommendations according to the conditions and criteria needed. This system uses the Simple Multi-Attribute Rating Technique (SMART) method to determine the best Bus Company based on various criteria needed. The system development process uses the waterfall method to facilitate systematic design with the simplest possible design and the data used is taken from case study needs through the interview process so that as a result of this system, travel owners get the most Bus Company recommendations according to their needs and the best ranking, and facilitate decision making with a more flexible time before use.
The Effect of Self-Regulated Learning Strategy on Student Learning Outcomes in Acid-Base Titration Material
Authors: Salsabila Marisa , Muchlis Muchlis
Published: August 2024

This research is based on the fact that students' learning outcomes in acid-base titration material in the low scores. The aim of this research is to investigate the effect of self-regulated learning strategies in acid-base titration material on student learning outcomes.
This research was quantitative research with a pre-experimental design with a one group pretest posttest design. This research began with a pretest, then at meeting 1, posttest 1 was given. After that, the implementation of Self-Regulated Learning (SRL) continued with posttest 2. The subjects used were 34 students at one of the State High Schools in Gresik. The instruments used were pretest and posttest sheets. Data analysis used was hypothesis testing and N-gain testing. Hypothesis testing showed that there was a significant difference between pretest and posttest 1 as well as between posttest 1 and posttest 2. Meanwhile the N-gain test shows that there was an improvement in learning outcomes from pretest and posttest 1 as well as from posttest 1 and posttest 2. The percentage of students who gain N-gain with medium criteria at meetings 1 and 2 was respectively 61.76% and 23.52% and for high criteria respectively 38.23% and 76.47%. The results of the hypothesis test and N-gain test showed that there was a positive influence on student learning outcomes in the acid-base titration material. Therefore, it can be concluded that SRL strategy-oriented learning influences learning outcomes and can improve student learning outcomes in acid-base titration material.