bluuebunny/crossref_metadata_2025 huggingface dataset:
Spectral analysis of the polarisation of drifting subpulses
Authors: Castelltort Schnaas Ander
Published: November 2022

Pulsars are among the most extreme objects in the Universe. Each one is born during a supernova – a dramatic explosion that happens when a bright star is many times bigger than our Sun and runs out of fuel. The heavy core of the star collapses under its own weight into something denser than the nucleus of an atom. Each pulsar has a magnetic field that is millions of times stronger than any that can be produced here on the Earth. Like a cosmic lighthouse, this magnetic field generates beams that sweep across the Galaxy with each rotation of the star (Gold, 1968); however, the underlying physics of the pulsar emission mechanism remains poorly understood after decades of study. Unlike the steady beam of a lighthouse, a pulsar's beam crackles and pops with lightning-like discharges of energy (Ruderman & Sutherland, 1975). By studying this highly dynamic signal, we learn about what generates the radio waves and what happens as they travel through the turbulent plasma in the pulsar's strong magnetic field. A relatively rare number of pulsars exhibit quasi-periodic variations in the polarization state of their emission (Primak et al., 2022). To provide new insight into the origin of this behaviour, I have developed a novel statistical method of studying quasi-periodic polarization fluctuations. I apply this technique to the first-discovered pulsar, and compare and contrast the results with previous work. The method can be applied to a wide range of radio pulsars and used to estimate the fraction of pulsars that exhibit quasi-periodic polarization fluctuations. In doing so, this experiment will provide new experimental constraints on theories of radio emission and propagation in the pulsar magnetosphere, and facilitate a deeper understanding of the physics of relativistic plasmas in strong magnetic fields.
Do oral health therapists need to collaborate?
Authors: Martin Melody
Published: November 2022

It is imperative oral health therapists (OHTs) collaborate with peers from other disciplines. Interprofessional collaboration contributes to improved health outcomes, improvements in health systems, and increased patient and practitioner satisfaction (World Health Organisation, 2010). The legislation provides a clear mandate for interprofessional collaboration. The Health Practitioners Competence Assurance Act (2019) clause 118 states professional regulatory authorities have a responsibility to promote collaboration across, and between health professionals in the delivery of health services. The World Health Organization (2010) explains that embedding interprofessional education (IPE) enables health graduates to develop the capability necessary to practice confidently as interprofessional collaborative practitioners. Despite these factors, IPE is not immersed within the AUT OHT curriculum. To inform and guide sustainable change in line with the evidence and legislative requirements, this study uses a hermeneutic phenomenological methodology to draw on AUT OHT educators lived experiences of interprofessional education and collaborative practice (IPECP), and applies an interpretative lens to understanding these experiences, informed by van Manen (1990). The findings from the research will provide insights that aim to inform future IPECP curriculum development. Taking an informed approach to developing IPE for AUT OHT students, it aims to prepare collaborative and practice-ready graduates, and ultimately improve the health outcomes of those they serve. In this presentation, I will highlight the importance of IPECP for OHT at AUT, share some of the stories told during the semi-structured interviews with AUT OHT educators on their lived experiences of IPECP and summarise my research to date.
Evaluation of osteoarthritic features in peripheral joints by ultrasound imaging: A systematic review
Authors: Molyneux Prue
Published: November 2022

The role of ultrasound imaging for osteoarthritis (OA) diagnosis in peripheral joints has not been clearly defined. To further understand this role, the objectives of this study were to determine how structural and inflammatory OA features in peripheral joints are assessed, defined and graded by ultrasound imaging. MEDLINE, CINAHL, Cochrane and SPORTDiscus databases were systematically searched in March 2021. To be eligible, studies needed to (1) include participants with peripheral joint OA, and (2) use grey scale and/or power Doppler ultrasound imaging to assess one or more ultrasound features in peripheral joints of the hands and feet. Methodological quality of all included studies was assessed using the Critical Appraisal Skills Program tool [1]. A total of 159 citations were identified for screening. Thirty-two articles were included for final analysis and were of good methodological quality. Thirty articles evaluated ultrasound features of hand OA and two assessed ultrasound OA features in the foot. There were inconsistencies between studies in terms of what ultrasound features were assessed, how these features were defined and what grading system was applied to determine degree of osteoarthritic change. The review found inconsistencies in the definition of synovial pathology. Consequently, it is unclear whether synovial pathology is best represented as separate entities or combined as a single domain, termed “synovitis”. How OA ultrasound features were defined and graded has largely been extrapolated from recommendations originally constructed for populations with rheumatoid arthritis. Given the prognostic value of synovitis for OA progression and that inflammation associated with OA is fundamentally different from that in rheumatoid arthritis [2, 3], the validity of applying definitions, grading systems and atlases originally developed for rheumatoid arthritis needs consideration. This review strengthens the case for further refinement and validation of OA definitions, grading systems and ultrasound atlases specific to peripheral joints.
Assessing operating conditions of silicone torsional vibration dampers of ship propulsion systems
Authors: Sibryaev Konstantin Olegovich , Pokusaev Mikhail Nikolaevich , Gorbachev Maxim Michailovich , Ibadullaev Adel Damirovich
Published: November 2022

The article considers the assessment of operational conditions of silicone torsional vibration dampers

of ship propulsion systems. The static data of the foreign company “Holset” on the average time of preventive repairs of silicone dampers with removable covers are given, the performance indicators of these devices are presented. The parameters of efficiency and technical state of the silicone dampers are determined. As it has been found out from the technical operation, the replacement of torsional vibration dampers is needed only if there appear any clear signs

of their malfunction or damage. The main methods of diagnostics of operating condition of silicone dampers are analyzed (diagnostics and determination of the residual resource based on the results of the torsiography procedure of the ship shafting, sampling the damper filler (silicone liquid) with further conducting the physico-chemical analysis. The key factors affecting the performance of silicone dampers are considered (state of the filler of polymethylsiloxane liquid (PMS-liquid), leakage of PMS-liquid, design of the silicone damper, resonant modes of the main engine operation). Conclusions are drawn about the optional correspondence of the appointed terms of operation of torsional vibration silicone dampers and their technical state; the need for periodic, timely troubleshooting; inefficient determining the operability and technical state of the dampers based on sampling the filler (silicone liquid).
ANALISA DAN PERANCANGAN SISTEM PEMASARAN UMKM TERINTEGRASI BERBASIS CLOUD SERVER
Authors: Latubessy Anastasya , Triyanto Wiwit Agus
Published: November 2022

ABSTRAK Usaha Mikro Kecil dan Menengah (UMKM) memberikan pengaruh positif bagi pertumbuhan ekonomi di negara kita. UMKM akan berkembang dengan baik jika didukung oleh sistem pemasaran yang baik pula. Sistem pemasaran dapat dikatakan berhasil, jika hasil yang produksi dari tiap-tiap UMKM dapat dikenal secara global. Untuk mempromosikan hasil produksi secara global, dibutuhkan media yang tepat. Kehadiran Internet sebagai indikator perkembangan dunia Teknologi dan Informasi saat ini, dapat dimanfaatkan sebagai media tepat dalam proses pemasaran hasil produksi UMKM. Namun, jumlah UMKM yang terus meningkat membutuhkan kapasitas daya tampung besar dalam sebuah sistem pemasaran terintegrasi. Cloud server merupakan teknologi yang menonjolkan fleksibilitas dan skalabilitas dalam penggunaan server. Hadir sebagai solusi tepat dalam pengembangan sistem terintegrasi. Sehingga pada penelitian ini, dilakukan analisa kebutuhan untuk menghasilkan pemodelan sistem pemasaran dengan menggunakan pemodelan UML (Unified Markup Language) dan juga melakukan perancangan arsitektur sistem berbasis cloud server. Kata kunci: Analisa, Perancangan, Sistem, Terintegrasi, UMKM, Cloud, Server.
visualización del espacio geográfico en las écfrasis del Libro de Alexandre con Recogito y Visone
Authors: Calarco Gabriel
Published: November 2022

El presente artículo se propone explorar la representación del espacio geográfico en las écfrasis del Libro de Alexandre. Con este fin, se utilizaron las herramientas gratuitas y abiertas Recogito y Visone para georreferenciar el texto y desarrollar una herramienta interactiva en línea, así como diferentes visualizaciones, que permiten explorar la información geográfica de esta obra. Mediante el análisis de estas visualizaciones se presenta una reflexión sobre lo que estas herramientas pueden aportar para la representación de la geografía en el poema, así como las limitaciones que presentan para trabajar con esta fuente específica. A partir de estas consideraciones se proponen algunas estrategias de intervención editorial, con el fin de acercar lo mejor posible el mundo cultural y la cosmovisión del espacio de la clerecía castellana del siglo XIII al público moderno a través del uso de estas herramientas.
relación con la luz. Las cartas de la Mujer Vampiro, la Verídica, una novela digital olvidada de Cristina Rivera Garza
Authors: Olaizola Andrés
Published: November 2022

El presente artículo se propone examinar Una relación con la luz. Las cartas de la Mujer Vampiro, la Verídica, una novela digital por entregas que Cristina Rivera Garza publicó entre el 2005 y el 2007. 
El objetivo del artículo es analizar cómo se despliega en esta novela digital por entregas uno de los procedimientos centrales en la poética de Rivera Garza, la expansión. Para ello, articularemos un análisis específicamente de contenido con una lectura distante a través del empleo de la herramienta digital Voyant Tools.
PENGGUNAAN ALAT PERAGA DALAM METODE BERCERITA UNTUK MENINGKATKAN PERBENDAHARAAN KATA ANAK 5-6 TAHUN
Authors: Agusriani Ade , Sumiati Siti , Ismail Wahyuni , Nurhayati Andi , Rachmatiah St
Published: November 2022

Improving vocabulary  in children is very important to be stimulated, , the more vocabulary mastered by children it can facilitate children in interacting and communicating with others. This study aims to determine whether the vocabulary mastered by children is able to re-discuss the story that has been heard through the method of storytelling using props in children aged 5-6 years. Community service research in the form of service learning was conducted in kindergarten Aisyiyah Branch 1 Sungguminasa with a number of participants as many as 3 children.  The instruments used in the form of props are images of animals that are cut out according to their shape and pasted on cardboard paper, besides the instruments used are also sheets of evaluation of implementation and intervention. Data were analyzed using descriptive statistics. The results of this study showed that the 3 participants ' language development was different, there were children who had dared to propose to retell stories that had been heard but still could not tell them in order, there were also children who could tell it well but needed more time because they were still hesitant and shy and among them there were children who only heard and listened to their friends tell stories. The findings in this study imply that storytelling methods can improve children's vocabulary, if they focus on listening and listening to the content of the story.
Assessing the Knowledge, Awareness, and Preventive Particles of Dengue Fever in Beled Hawo District, Somalia
Authors:   Medical Doctor, Al-Huda Hospital, Dollow, Gedo, Somalia, Gaal Ali Osman
Published: November 2022

Dengue fever is a viral infection transmitted by mosquitoes, particularly in tropical and sub-tropical environments. The rising prevalence of the disease is posing a significant threat to public health across Sub-Saharan Africa. The primary goal of the study is to evaluate the level of knowledge and awareness as well as the preventive measures implemented in the Beled Hawo district of Gedo, Somalia. Methodology: A cross-sectional study design was used for the investigations, and a structured questionnaire was used to gather sociodemographic data as well as knowledge-based dengue fever treatment and prevention practices among the residents of Beled Hawo District. Findings: The results indicate that a majority of 78.1% and 86.4% of the respondents were knowledageble and had a reasonable understanding of the disease respectively. Notwithstanding this, a majority of them were mistaken about the peak biting period of the Aedes mosquito. In addition, 61 percent of responses identified fever as a typical disease symptom. Futhermore, some had the wrong impression of the preventive measures as more than 17% of those surveyed failed to mention environmental cleanup as a mitigating strategy. The study results may be useful to local authorities and healthcare institutions as it provides information on the gravity of the dengue problem in particular pockets of Beled Hawo district, thus aid in informing them on necesary mitigation measures and local health programming strategies. The study may also inform policy makers at the Ministry of health and health departments. The study shall also contribute to the academia and serve as a source of literature in guiding future researches.
Musculoskeletal Pain among Work from Home Population during the COVID-19 Pandemic - A Cross Sectional Study
Authors:   Postgraduate, Department of Community Medicine, Chettinad Hospital and Research Institute, Tamil Nadu, India, S Manju
Published: November 2022

Background: The COVID-19 pandemic and the subsequent lockdowns had brought many changes in the working patterns of the people. Work from home, which has been becoming the new normal is suspected to increase the prevalence of musculoskeletal disorders and stress. Aim: To assess the prevalence of musculoskeletal pain among the work from home population and hence bring the required changes to ergonomics. Methods and Materials: This is a cross-sectional study, conducted among the urban population (IT employees) of Chengalpattu district. A total of 180 participants were included in the study. Standardized Nordic Musculoskeletal Questionnaire, adapted to fit the current study was used as a self-administered online questionnaire to collect data from the participants. Results: Prevalence of musculoskeletal disorders among work from home population was found to be 84% with low backache being the most common musculoskeletal pain. Around 50% of the participants either had an increase in pain (18.9%) or reported that the pain started only during the lockdown (30.6%). Majority of the participants (55.6%) had more than 8 hours of work per day, which may be attributed to the increase in musculoskeletal pain. Perceived stress levels were found to be increased during the work from home period. Conclusion: The absence of ergonomic office furniture may lead to increased faulty posture increasing the musculoskeletal pain, hence awareness on factors like right posture, using the right furniture should be ensured among home working population. By bringing out the required changes in ergonomics for the home working population, the prevalence of musculoskeletal disorders and stress can be reduced.
Improving the Supply Chain Management
Authors: Xu Lijuan , Zhang Mengze , Abdullayeva Irada
Published: November 2022

This paper develops a methodological approach to assessing the supply chain management in small- and medium-sized businesses with further testing it in the companies in the post-Soviet economies. The research objectives were achieved in terms of a sophisticated multi-country project resulting in assessment of the supply chain management for small- and medium-sized businesses in Russia, Kazakhstan, and Azerbaijan (256 businesses in total). The study was implemented through a phased application of online survey methods using closed-ended single-choice questions, including a 5-point Likert scale, mean score ranking, and ABC analysis using the Pareto principle. The assessment showed that, regardless of the surveyed country, almost all respondent businesses use a reactive supply chain design. Since the reactive design does not allow for the implementation of resilient supply chain development, the recommended practices, which have been developed during the pilot phase, deal with improving the supply chain management and gradual transformation of the reactive design into a cooperative management model to ensure resilient supply chain development under uncertainty.
Perceptions, Choices and Usage of Ecological Household Chemicals: Results from an Online Citizen Survey in Latvia
Authors: Klavina Aneka , Kalpisa Maija , Paegle Linda , Akulova Lasma , Vanadzins Ivars
Published: November 2022

Chemical products are widely used in our everyday activities. As the availability and accessibility of ecological chemical products increases, the usage of these products should be promoted and encouraged since it is better for the environmental and human health. However, there is a gap between individual perceptions on these products and actual usage, therefore the aim of this study was to compare the knowledge and perceptions on chemical products and their labelling in Latvian adult citizens and whether this knowledge impacts their choices and usage of chemical products. An online survey was used to gather data from 412 respondents (21.8 % (n = 90) men, 78.2 % (n = 322) women, average age 39.5 years, 77.2 % (n = 318) had obtained higher education). 62.2 % (n = 237) of respondents use household chemicals every day: 6.7 % (n = 25) more than five times a day, 25.9 % (n = 99) two to five times a day and 29.6 % (n = 113) at least once a day. Although 78.2 % (n = 257) of respondents indicated that it was important to them that the household chemicals are ‘ecofriendly’, only 7.4 % (n = 28) of them responded that they always purchase eco-labelled chemical products and 60.1 % (n = 229) do it sometimes. Almost a third of respondents (28.9 %, n = 110) have not payed attention whether the product has an eco-label. Survey data also shows that 91.9 % (n = 351) respondents’ choice regarding household chemicals is affected by their previous experience, including product effectiveness, product ‘ecofriendliness’ (62.1 %, n = 237) and product price (59.2 %, n = 226). Many respondents have correctly identified eco-labels, but at the same time, more than a third of respondents (17.9–39.8 %) mistake other labels to be eco-labels as well.
Bioinformatics analysis of various signal peptides for periplasmic expression of parathyroid hormone in E.coli
Authors: Juibari Aref Doozandeh ,   Department of Biology, University of Guilan, Rasht, Iran, Ramezani Sina ,   Department of Biology, University of Guilan, Rasht, Iran, Rezadoust Mohammad Hosein ,   Faculty of Agriculture, University of Guilan, Rasht, Iran,   Mohammad Hosein Rezadoust, Ph.D in nanobiotechnology, Faculty of Agriculture, University of Guilan, Rasht, Iran, E-mail: Rezadoost2012@gmail.com
Published: November 2022

Hypoparathyroidism is a rare endocrine disease which is characterized by the deficiency of serum calcium levels. RhPTH is prescribed as a therapy for the management of refractory hypoparathyroidism. The aim of this study is to investigate 32 signal peptides of gram-negative bacterial origin and evaluate their potential for efficient secretion of recombinant human PTH (1–84)In E.coli to obtain higher expression of recombinant PTH in bacterial systems by using this fusion partner. SignalP and ProtParam servers were employed to predict the presence and location of signal peptide cleavage sites in protein sequence and computation of various physical and chemical parameters of protein respectively. Also, SOLpro server was applied for prediction of the protein solubility. Then ProtComp and SecretomeP online servers were employed to determine protein location. The evaluations showed that theoretically two signal peptides Lipopolysaccharide export system protein LptA (lptA) and Periplasmic pH-dependent serine endoprotease DegQ (degQ) are the most appropriate signal peptides examined. Due to the lack of post-translational modification in PTH, its periplasmic expression has preferences. Based on the results of this study, using bioinformatics and reliable servers signal peptides with appropriate secretory potential can be obtained which lead to the highest expression level.
The Level and Frequency of Faculty Incivility as Perceived by Nursing Students of Lorestan University of Medical Sciences
Authors: Mohammadipour Maryam ,   Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran, Hasanvand Shirin ,   Department of Nursing, Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran,   Shirin Hasanvand, Department of Nursing, Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. Tel: 09166690887, Fax: 06633120140. E-mail: hasanvand.sh@lums.ac.ir, Goudarzi Fateme ,   Department of Nursing, Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran, Ebrahimzadeh Farzad ,   Department of Biostatistics and Epidemiology, Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran, Pournia Yadollah ,   Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
Published: November 2022

Background

Little evidence exists concerning students’ perception of faculty incivility. Given the growing trend of incivility and the stressful nature of these behaviors, the present study aimed to investigate the level and frequency of faculty incivility as perceived by nursing students.

Methods

A stratified random sample of 178 students from four nursing faculties of Lorestan University of Medical Sciences participated in the present cross-sectional study. The Incivility in Nursing Education-Revised Survey, consisting of 24 items, was used to investigate the prevalence and frequency of faculty incivility, and the mean and frequency of each item was calculated separately. The data were analyzed using descriptive and analytical statistics (chi-square, independent t-test and analysis of variance), and the significance level was set at 0.05.

Results

Most of the participants were single, did not live in a dormitory, and ranged in age from 19 to 23. From their perspective, disrespect, physical threat, property damage, and physical violence were of paramount importance. 61.8% of them argued that they had “sometimes” and “always” experienced “unfair assessment” during the last year. Creating codes of behavior, enhancing awareness of civility, and developing and implementing policies for managing incivility were proposed as the most important strategies for improving civility.

Conclusion

Faculty members should be prepared for establishing friendly and respectful relationships, effective teaching, and applying a reality-based assessment. Identifying different and prevalent kinds of faculty incivility and making faculty members aware of them paves the way for faculty members to rethink their performance.
Designing Data Elements and Minimum Data Set (MDS) for Creating the Registry of Patients with Gestational Diabetes Mellitus
Authors: Ahmadi Maryam ,   Department of Health Information Management, School of Management and Medical Information Sciences, University of Medical Sciences, Tehran, Iran, Mirbagheri Esmat ,   Department of Health Information Management, School of Management and Medical Information Sciences, University of Medical Sciences, Tehran, Iran,   Esmat Mirbagheri, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran, Tel.: +98 9171876641; Fax: +98 21 88883334, E-mail: Mirbagheri.e@iums.ac.ir
Published: November 2022

The prevalence of gestational diabetes mellitus (GDM) is increasing in Iran. Collection of patients’ data is commonly conducted through using medical records. However, for providing a structured reporting based on the information needs, a minimum data set is a fast, inexpensive, and suitable method. For exchanging high-quality data between different healthcare centers and health monitoring organization, the data are required to be uniformly collected and registered. The present study aims at designing an MDS for creating the registry of GDM. The present study is an applied one, conducted in two stages, with a qualitative Delphi method in 2018. In the first stage of the study, it was attempted to extract the data elements of mothers with GDM, through reviewing the related studies and collecting these patients’ data from the medical records. Then, based on the results of the first stage, a questionnaire including demographic, clinical, and pharmaceutical data was distributed among 20 individuals including gynecologists, pharmacists, nurses, and midwives. The validity of the questionnaire was examined by a team of experts and its reliability was examined by using Cronbach’s alpha. Data analysis was conducted using descriptive statistics (frequency, percentage, and mean) and excel. An MDS of gestational diabetes mellitus was developed. This MDS divided into three categories: administrative, clinical, and pharmaceutical with 4, 18, and 2 sections and 35, 199, and 12 data elements, respectively. Determining the minimum data sets of GDM will be an effective step toward integrating and improving data management of patients with GDM. Moreover, it will be possible to store and retrieve the data related to these patients.
Correlation between Pregnancy Related Weight Gain, Postpartum Weight loss and Obesity: a Prospective Study
Authors: Nartea Roxana ,   National Institute of Rehabilitation and Balneology, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Mitoiu Brindusa Ilinca ,   National Institute of Rehabilitation and Balneology, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Brindusa Ilinca Mitoiu, MD, PhD, National Institute of Rehabilitation and Physical Medicine, 11 a Ion Mihalache Road, District 1, Bucharest, Romania; Phone +40723552797, E-mail: brindusailinca@yahoo.com, Nica Adriana Sarah ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: November 2022

Weight gain during pregnancy can be a real risk factor for long-term obesity which has implications in all areas of medicine. This study is designed to assess pregnancy-related weight gain and postpartum weight loss, to identify a possible correlation between weight gain during pregnancy and the risk of obesity in the late postpartum period. The batch comprised 306 women, hospitalized in the Obstetrics and Gynecology Section of the “Nicolae Malaxa” Clinical Hospital between June - November 2017. During this study, we assessed the weight status using the Weight, Body Mass Index, Height, and Abdominal Circumference. These parameters were clinically assessed in three periods pre-pregnancy, early postpartum period, late postpartum period. We also collected data on the evolution of the pregnancy using the anamnesis and the personal pregnancy monitoring sheet. Pregnancy and postpartum period represent a key moment in women’s lives in which the risk of obesity is real. Understanding women experiences with weight changes during pregnancy and postpartum period can improve the management of losing weight following pregnancy, avoid long-term weight gain and so reduce the risk for obesity. Also, the correct management of obesity should include the assessment of somatic disorders that may cause major dysfunction, requiring complex rehabilitation programs.
The Effects of Ventriculoperitoneal Shunt on Gait Performance
Authors: Baltateanu Dumitru ,   Elias University Emergency Hospital, Bucharest, Romania,   Dumitru Baltateanu, Elias University Hospital, Department of Neurosurgery, 17 Marasti Bd, Sector 1, Bucharest, Romania, Tel: +40723266122; E-mail: dorubaltateanu@yahoo.com, Ciobanu Ileana ,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Berteanu Mihai ,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Published: November 2022

Most studies on patients with normal pressure hydrocephalus (NPH) regard pre-post Tap test and long-term follow-up after shunt surgery. Quantitative and qualitative assessment tools specific to rehabilitation medicine can provide an objective measurement of the benefit of the neurosurgical intervention at 1-month follow-up. The aim of this retrospective study was to assess the early benefit of the ventriculoperitoneal shunt with low or medium pressure valve on the gait capacity of persons with NPH, one month after surgery. This is a retrospective study reviewing 19 inpatients with NPH who underwent neurosurgery for ventriculoperitoneal shunt with low or medium pressure valve, one month after a positive result on a tap test, in a 5-year period. The assessments regarding the gait abilities were performed 24 hours before the surgical intervention and one month after surgery. Assessment tools used were: the 3 meters Timed Up and Go Test (TUG), the 10 Meters Walking Test (10MWT) and the Berg Balance Scale. A positive response to the tap test predicted improvements of gait and balance in patients with NPH after shunt surgery. Best results in regards to gait and balance are achieved when early diagnosis and intervention are performed. Complex comorbidities generate and enhance significant and persistent gait impairment.
Uropathogenic Escherichia coli virulence characteristics and antimicrobial resistance amongst pediatric urinary tract infections
Authors: Alfuraiji Narjes ,   1. Department of Pharmacology, College of Medicine, University of Kerbala, Kerbala, Iraq,   Narjes Alfuraiji, Department of Pharmacology, College of Medicine, University of Kerbala, Kerbala, Iraq. E-mail address: narjes.c@uokerbala.edu.iq,   https://orcid.org/0000-0001-5338-6443, Al-Hamami Amal ,   2. Department of Pediatrics, College of Medicine, Aliraqia University, Baghdad, Iraq,   https://orcid.org/0000-0001-7957-1372, Ibrahim Maysaa ,   2. Department of Pediatrics, College of Medicine, Aliraqia University, Baghdad, Iraq,   https://orcid.org/0000-0001-9573-6894, Rajab Hassan Khuder ,   3. Department of Pharmacology, College of Medicine, Tikrit University, Tikrit, Iraq,   https://orcid.org/0000-0003-0297-5461, Hussain Balsam Waleed ,   4. Department of General Surgery, Al-Yarmouk Teaching Hospital, Baghdad, Iraq,   https://orcid.org/0000-0003-4394-5517
Published: November 2022

Uropathogenic Escherichia coli (UPEC) harbors virulence factors responsible for bacterial adhesion and invasion. In addition, the bacterium is accountable for the occurrence of pediatric urinary tract infections globally and is becoming problematic due to the emergence of antimicrobial resistance. The current research investigated UPEC prevalence, virulence characteristics, and antimicrobial resistance in pediatric urinary tract infection (UTI). 200 urine specimens were taken from hospitalized pediatric patients who suffered from UTIs. E. coli was recovered from urine specimens using the microbial culture. Disc diffusion method was used to assess antimicrobial resistance and polymerase chain reaction (PCR) to assess the virulence factors distribution amongst the UPEC bacteria. Seventy-five out of 250 (30.00%) urine samples were positive for the UPEC bacteria. The UPEC prevalence amongst pediatric patients was 25.83% and 33.84%, respectively. UPEC bacteria harbored the maximum resistance toward gentamicin (45.33%), ampicillin (44.00%), and ciprofloxacin (40.00%). Cytotoxic necrotizing factor 1 (Cnf1) (53.33%) and pyelonephritis-associated pil (pap) (42.66%) were the most frequently identified virulence factors amongst the UPEC bacteria. The high prevalence of UPEC isolates harboring antimicrobial resistance and virulence factors suggest that diseases caused by them need more expansive healthcare monitoring with essential demand for novel antimicrobials.
Islamic praying changes stress-related hormones and genes
Authors: Sobhani Vahid ,   1. Exercise Physiology Research Center, Lifestyle Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran,   https://orcid.org/0000-0002-4513-0488, Manshadi Ehsan Mokari ,   2. Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran,   https://orcid.org/0000-0002-6081-7448, Aghajani Jafar ,   3. Department of Molecular Genetics, Faculty of Marvdasht, Islamic Azad University, Shiraz, Iran,   https://orcid.org/0000-0003-1363-2018, Hatef Boshra ,   2. Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran,   Boshra Hatef, Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. E-mail: boshrahatef@bmsu.ac.ir,   https://orcid.org/0000-0002-2638-3463
Published: November 2022

Islamic praying (Namaz) can be considered a mental, spiritual, and physical practice. The study aimed to investigate the early effect of Namaz on stress-related hormones and the expression of stress-induced genes such as IL6 and BDNF. Eighty-three healthy women and men who continually practice Namaz participated in the study. The saliva samples were taken before and after Namaz to measure cortisol and alpha-amylase hormone levels. Also, to evaluate the expression of BDNF and IL6 genes, 11 specimens were selected randomly. Based on baseline sampling, the participants were classified into three groups: cortisol levels lower than 5, between 5–15, and upper than 15 ng/ml. The results indicated that cortisol significantly increased and decreased in the first and third groups after Namaz, respectively. In addition, the increase of alpha-amylase also occurred in subjects with a low baseline level of its concentration. Regarding genetic expression examination, there was a significant decrease in BDNF gene expression after the Namaz. In addition, the change of cortisol and alpha-amylase hormones after Namaz related to the baseline level changed to approach the optimal range after Namaz. These findings were reported for the first time and need more studies.
The bioengineered HALOA complex induces anoikis in chronic myeloid leukemia cells by targeting the BCR-ABL/Notch/Ikaros/Redox/Inflammation axis
Authors: Singh Vivek ,   1. Department of Biochemistry, King George's Medical University, Lucknow, Uttar Pradesh, India, Singh Ranjana ,   1. Department of Biochemistry, King George's Medical University, Lucknow, Uttar Pradesh, India,   Ranjana Singh,Department of Biochemistry, King George's Medical University, Lucknow, Uttar Pradesh, India. E-mail: ranjanasingh.2509@rediffmail.com, Mahdi Abbas Ali ,   1. Department of Biochemistry, King George's Medical University, Lucknow, Uttar Pradesh, India, Tripathi Anil Kumar ,   2. Department of Clinical Hematology, King George's Medical University, Lucknow, Uttar Pradesh, India
Published: November 2022

Blast crisis (BC) is an outcome that arises during the treatment process of chronic myeloid leukemia (CML), which is possibly attained by the dysregulation of the Notch and Ikaros signaling pathways, BCR-ABL translocation, redox, and inflammatory factors. This study demonstrated that biotherapeutic agents target aberrant molecular axis in CML-BC cells. The HALOA complex was synthesized by simple mixing of apo α-lactalbumin with oleic acid, which manages to inhibit BCR-ABL (b3a2 in K562 cells) translocation. It elevates the production of reactive oxygen species (ROS), reactive nitrogen species (RNS), and protein carbonyl, which induces DNA fragmentation in K562 cells but not in NIH cells. The complex manages to reduce the toxicity surrounding apoptotic cells by enhancing the production of superoxide dismutase (SOD) and the total antioxidant level. The HALOA complex increases leptin to maintain normoxic conditions, ultimately preventing angiogenesis. This complex downregulates the expression of IL-8 and MMP-9 and elevates the expression levels of Notch 4, Ikaros, and integrin alpha-D/CD-11d (tumor-suppressive), which conjointly prevents inflammation, metastasis, and epithelial-mesenchymal transition (EMT) in CML cells. Meanwhile, the complex downregulates Notch 1 and 2 (oncogenic), consequently inducing anoikis in CML cells. Overall, the HALOA complex shows credibility by targeting the combined molecular factors responsible for the pathogenesis of the disease and will also help to overcome MDR conditions in leukemia.
The prevalence of common CFTR gene mutations and polymorphisms in infertile Iranian men with very severe oligozoospermia
Authors: Jafari Leyla ,   1. Department of Biology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran, Safinejad Kyumars ,   2. Department of Biology, Borujerd Branch, Islamic Azad University, Borujerd, Iran,   Kyumars Safinejad, Department of Biology, Borujerd Branch, Islamic Azad University, Borujerd, Iran. E-mail: q_safinejad@yahoo.com, Nasiri Mahboobeh ,   1. Department of Biology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran, Heidari Mansour ,   3. Department of Medical Genetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran, Houshmand Massoud ,   4. Department of Medical Genetics, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran
Published: November 2022

Due to progress in infertility etiology, several genetic bases of infertility are revealed today. This study aimed to investigate the distribution of mutations in the CFTR gene, M470V polymorphism, and IVS8 poly T. Furthermore, we aimed to examine the hotspot exons (4, 7, 9, 10, 11, 20, and 21 exons) to find a new mutation in cystic fibrosis transmembrane conductance regulator (CFTR) gene among infertile Iranian men very severe oligozoospermia (<1 million sperm/mL ejaculate fluid). In the present case-control study, 200 very severe oligozoospermia (20–60s) and 200 fertile men (18–65s) were registered. Five common CFTR mutations were genotyped using the ARMS-PCR technique. The M470V polymorphism was checked out by real-time PCR, and poly T and exons were sequenced. The F508del was the most common (4.5%) CFTR gene mutation; G542X and W1282X were detected with 1.5% and 1%, respectively. N1303K and R117H were detected in 0.5% of cases. F508del was seen as a heterozygous compound with G542X in one patient and with W1282X in the other patient. Also, in the case of M470V polymorphism, there are differences between the case and control groups (p=0.013). Poly T assay showed statistical differences in some genotypes. The study showed no new mutation in the exons mentioned above. Our results shed light on the genetic basis of men with very severe oligozoospermia in the Iranian population, which will support therapy decisions among infertile men.
Immunological parameters of recurrent miscarriages among women in Thi-Qar province
Authors: Hamadi Ghaneemah Malik ,   1. Department of Community Health, Nasiriyah Technical Institute, Southern Technical University, Thi-Qar, Iraq,   Ghaneemah Malik Hamadi, Department of Community Health, Nasiriyah Technical Institute, Southern Technical University, Thi-Qar, Iraq. E-mail: ghaneemahm@stu.edu.iq,   https://orcid.org/0000-0003-0811-7353, Lafta Sally Fadhel ,   2. Public Health Laboratory, Thi-Qar, Iraq,   https://orcid.org/0000-0002-3985-0710
Published: November 2022

Recurrent miscarriage (RM) is defined as the loss of pregnancy three or more consecutive times in the first and second trimester, which in some cases occurs due to immune abnormalities. This study aimed to assess some immunological parameters in women with recurrent miscarriages, including the level of antiphospholipid antibody (APA), anticardiolipin (ACA), antinuclear antibody (ANA), complement C3 and C4, and interleukine-3 (IL-3). We included 100 patients together with 100 healthy women as a control. ELIZA was used to measure some types of autoantibodies. APA and ACA significantly increased (P≤0.05) in patients compared to control. In addition, 29% of the patients were positive for antinuclear antibodies (ANA), while the control subjects had negative results for these autoantibodies. Regarding the complement, the serum levels of C3 and C4 were significantly elevated in the serum level of patients when compared to the control group, but in treated patients (heparin and low-dose aspirin), the levels of the complement (C3 and C4) showed a significant decrease in patients compared to total controls. Cytokine level (IL-3) significantly decreased in untreated patients 302.78 pg/ml compared to treated patients (741.57 pg/ml). Antiphospholipid antibodies are more prevalent among women with recurrent miscarriages and are also believed to be the result of abnormal autoimmune activation.
متعة الطَّرَد في رحلات أبي نواس
Authors: Abbawoy Hussein Ahmed , Jasim Asmaa Saber
Published: November 2022

يعنى هذا البحث بدراسة متعة الطَّرَد في شعر أبي نواس إذ يعد الطَّرَد أو الصيد ظاهرة اجتماعية انحدرت إلى العصر العباسي من العصور التي سبقته ولم يكن مقصوراً على تسلية أُمراء القوم وذوي الوجاهة منهم ممن اتخذوه ميداناً لمتعتهم ورياضتهم ، بل ظل في جانبه النفعي مهنة ارتـزاق لبعض المعوزين . وقد كان لهــذا النـشاط الــواسع بوصفه ريـاضةً تُمارَس للمتعة والتسلية والهوايـة أن شغـف به خلفاء بني العباس وكبار القـوم وبـاقتناء جوارحـه وضواريـه وبـدت آثـاره واضحـة في الـمجتمع العبـاسي حينـئذٍ وراح النـاس يقلـدون الـمـلوك والسـادة ، حتى استشرى وعـمَّ جميع الطبقات، ليغدو أهم وسائـل تزجية أوقات الفراغ ، ونوعاً من الترفيه الحضاري في صورة أكثـر مـلاءمة لمقـتضيات حـال أنس الجـماعة المترفة وانبساطها.
التوزيع الجغرافي للسكان وكثافتهم في محافظة صلاح الدين لسنتي (2014، 2019)
Authors: Shalal Adel Taha
Published: November 2022

يكشف هذا البحث معرفة واقع توزيع السكان وكثافتهم في محافظة صلاح الدين من خلال عرض تحليلي وموضوعي لطبيعة ونمط ذلك التوزيع في حضر وريف المحافظة وبيان جملة العوامل الجغرافية المؤثرة فيه سواء كانت الطبيعية منها ام البشرية, والذي يسعى البحث الى تناولها وتحديد مستويات تأثيرها على تباين التوزيع الجغرافي لسكانها من وجهة نظر ديموغرافية وبيئية مختلفة.
   وتهتم دراسته في عرض صورة واضحة عن تقييم الابعاد والاتجاهات الحالية والمستقبلية لتوزيع السكان وأنماطه المختلفة بين الوحدات الادارية لمنطقة الدراسة وفقاً لأوجه العلاقات السكانية المساحية فيها ومقدار أثر الارتباط القائم بينها, ومدى انعكاسه على تباينه المكاني بعامة وحجم المعوقات التي تواجه سبيل توزيعه على مساحتها الجغرافية بنحو خاص, وبالتالي إمكانية وضع الحلول والمعالجات المناسبة له, هذا وقد خلص البحث في مخرج معطياته ونتائجه المتحققة الى وجود حالة من الاختلال والتباين في توزيع سكان منطقة الدراسة طبقاً لأهمية الموقع ونمط التركز السكاني فيها, فضلاً عن شكل التوزيع غير المتوازن في بعض مناطق واجزاء اخرى منها, والتي تعود اساساً الى وجود قصور لدى المعنيين في التخطيط السكاني والبيئي فيها على مستوى توزيع السكان في الحضر والريف, الى جانب تلك العوامل      الجغرافية المؤشرة آنفاً, والتي رسمت بمجموعها ملامح التوزيع الفعلي للسكان وكثافته في المحافظة.
التوزيع الجغرافي للصناعات الإنشائية وعوامل توطنها في قضاء الحويجة
Authors: Abdullah Sabah Othman , Hamid Nasser Darwish
Published: November 2022

تحتل الصناعات الإنشائية مكانة مهمة ومتميزة ليس على صعيد قضاء الحويجة فحسب بل وعلى صعيد المحافظة والقطر ككل , إذ إن أهميتها تتجلى بكمية وأنواع المنتجات للصناعات الإنشائية التي تقوم في انتاجها , فضلا" عن استيعابها أعدادا" كبيرة من اليد العاملة والمساعدة في القضاء على البطالة, إذ إن معظم هذه الصناعات تعتمد على المواد الأولية المحلية والتي توجد في اغلب أنحاء القضاء. اذ تتجلى أهمية هذه الصناعات بارتباطها الوثيق بالنمو السكاني والتطور الحضري وزيادة الاهتمام في مشاريع الاسكان وتنمية البيئة الارتكازية بشتى انحاء القضاء والمحافظة , ولا سيما المنتجات الاساسية كالبلوك والغسالات والكسارات وانواع البلاط المختلفة , اذ إن قيام أكثر من(117) صناعة من الصناعات الإنشائية في القضاء وتوزيعها على مركز ونواحي القضاء وإن كان هذا التوزيع يتصف بالتباين , و يعود هذا الى توفر المقومات الطبيعية والبشرية والانشطة الاقتصادية. وقد تطرق البحث الى التوزيع الجغرافي للصناعات الإنشائية , ويأتي في المرتبة الاولى مركز القضاء الذي يحتوي على (59) منشأة صناعية, تأتي بالمرتبة الثانية ناحية الزاب وتظم (38) منشأة صناعية, وجاءت بالمرتبة الثالثة ناحية العباسي التي تحتوي على (17) منشأة صناعية, وتأتي في المرتبة الاخيرة ناحية الرياض التي تحوي على (3) منشأة صناعية فقط من مجموع الصناعات الإنشائية في القضاء, وهنا يتضح التباين الكبير في توزيع الصناعات الإنشائية بين النواحي الادارية في القضاء.
Hellenistic Philosophy in Contemporary Intellectual Culture
Authors: Brovkin V. V.
Published: November 2022

The article deals with the place of Hellenistic philosophy in contemporary culture. It is established that the revival of interest in Hellenistic philosophy began at the end of the XX century and was associated with the research of P. Hadot and M. Foucault. The idea of these authors about Hellenistic philosophy as an art of living based on certain spiritual practices has become widespread in modern intellectual circles. It is shown that the philosophical teachings of Hellenism, especially Stoicism and Epicureanism, claim today to be a spiritual guide to life. Modern psychotherapy turns to Stoicism for help in the treatment of psychological disorders. Some ideas of Hellenistic philosophers continue to remain relevant in the field of socio-political relations.
Nutritional rehabilitation in children with Pierre Robin syndrome
Authors: Vora Ayushi Amit , Mathur Radhika , Prabhu Sanjay B.
Published: November 2022

Pierre Robin Syndrome (PRS) or sequence is a common craniofacial abnormality characterised by micrognathia, which causes glossoptosis and upper airway obstruction. This causes feeding difficulty resulting in severe malnourishment. Cleft plate is also commonly seen in this condition. Here, we present three cases less than 6 months of age with PRS and concurrent nutritional compromise. Common presenting symptoms included respiratory distress, stridor, cyanosis, and poor growth. In addition, caregivers had difficulty in feeding these children, resulting in severe acute malnutrition requiring hospitalization. These children had to undergo early surgical intervention in the form of tongue lip adhesion and jaw advancement procedures to ensure better airway resolution and nutritional outcomes. They were, then, started on F-75 formula with improved methods of feeding as per severe acute malnourishment under 6 months protocol, which resulted in adequate weight gain and good overall outcome.
An unusual case of extrapulmonary sequestration presenting as vomiting in a neonate
Authors: Patwardhan Leena , Khawale Mausmi , Mamtora Dhruv
Published: November 2022

Pulmonary sequestration is a rare, mostly sporadic disorder, with an incidence of 0.1–6% of all congenital lung malformations. It is also called as bronchopulmonary foregut malformation (BPFM) or accessory lung. A 16-day-old female child presented with vomiting and inability to take feeds. She was investigated further and differentials included foregut duplication cyst and BPFM. Surgical exploration confirmed the diagnosis of a BPFM. Delay in diagnosis may lead to complications such as torsion and sepsis.