bluuebunny/crossref_metadata_2025 huggingface dataset:
Propuesta de planificación lingüística para la inclusión de estudiantes no hispanohablantes en el sistema escolar chileno
Authors: Llopis i Alarcón Moisés , Flores Figueroa Claudia , Bahamondes Rivera Rosa
Published: December 2024

La llegada de estudiantes no hispanohablantes al sistema educativo chileno ha puesto de manifiesto la necesidad urgente de contar con un conjunto de acciones y estrategias integrales que aborden este fenómeno multidimensional. El presente trabajo articula una propuesta de planificación lingüística basada en cuatro ejes complementarios: 1) el desarrollo de la competencia intercultural, 2) la enseñanza de español como lengua adicional, 3) la enseñanza de contenidos curriculares en español, y 4) el reconocimiento y puesta en valor de la lengua materna o primera. Esta propuesta está diseñada a partir de las necesidades planteadas por la investigación precedente y mediante un trabajo de cinco años en un grupo de establecimientos públicos en tres regiones de Chile con alta matrícula de estudiantes no hispanohablantes.
De La Malinche al malinchismo: la complejidad de un destino único
Authors: Fernández dos Santos Mirta
Published: December 2024

Esta unidad didáctica ofrece una aproximación cultural a La Malinche, una controvertida figura histórica y nativa americana que jugó un papel fundamental en la conquista de México. Gracias a su conocimiento de idiomas (náhuatl, maya, español), pasó de ser esclava a ser intérprete, consejera y socia de Hernán Cortés. Por su fidelidad a los invasores, su nombre se convirtió en sinónimo de deslealtad en México. Así, la representación de La Malinche que impregnó la cultura mexicana desde el siglo XVI hasta finales del siglo XIX es la de una mujer traidora. Sin embargo, a lo largo del siglo XX, el revisionismo histórico-cultural ha empezado a operar cambios en el tratamiento y recepción de este conocido personaje del mundo hispánico, centrándose para ello en sus circunstancias biográficas desfavorables y en su papel como fundadora o madre de la nación mexicana.
La certificación de ELE en Grecia e Italia en la actualidad
Authors: Rammou Eirini
Published: December 2024

En los últimos años ha sido notorio el interés mostrado por dos países mediterráneos, Grecia e Italia, por el aprendizaje del español como lengua extranjera (ELE), lengua oficial de otro país mediterráneo, España, y de veinte países más en todo el mundo. También ha sido relevante la importancia que dan los griegos y los italianos a la certificación de ELE con su respectiva participación en los exámenes. El objetivo del presente estudio es presentar, de forma detallada, la situación actual de la certificación de ELE en Grecia e Italia. Además, se presentan datos generales de cada certificación y su estructuración. Asimismo, describe el estado actual del español como LE (lengua extranjera), tanto en Grecia como en Italia. Las conclusiones derivadas de esta investigación evidencian el interés mostrado por los griegos y por los italianos en el aprendizaje y certificación de ELE, así como su posible incremento en el futuro, teniendo en cuenta la realidad conformada en el ámbito de ELE con el pasar de los años y los estándares diferentes de ambos países.
Okula Hazırbulunuşluk: Tüm Yönleri ile Okula Geçiş
Authors: Eti İnanç , Yurtal Filiz , Akkaya Alıcı Yasemin , Polat Pınar , Özbek Serap , Çağlar Kabacık Sedef , Özer Yanarkaya Habibe , Dikici Sığırtmaç Ayperi
Published: December 2024

Okula Hazırbulunuşluk ve Okul Sisteminin Tarihi
Ebru DERETARLA GÜL
İnanç ETİ
Okula Hazırbulunuşluk ve Çocuğun Gelişimsel Özellikleri
Filiz YURTAL
Okula Hazırbulunuşluk: Bakış Açıları, Kuramlarve Teoriler
Gülsüm HOŞ
Ülkelerin Okula Hazırbulunuşluk Politikaları
Yasemin AKKAYA ALICI
Okula Hazır Bulunuşluğun Değerlendirilmesi
Pınar POLAT
Okula Hazırbulunuşlukta Çocuk ve Öğretmenın Rolü
Serap ÖZBEK
Okula Hazırbulunuşlukta Aile ve Toplumun Rolü
Sedef ÇAĞLAR KABACIK
Risk Altındaki Çocukların Okula Hazırbulunuşluğu
Habibe ÖZER YANARKAYA
Ayperi DİKİCİ SIĞIRTMAÇ
Synthesis of acenaphthylene-fused heteroarenes and polyoxygenated benzo[j]fluoranthenes via a Pd-catalyzed Suzuki–Miyaura/C–H arylation cascade
Authors: Yence Merve , Ahmadli Dilgam , Surmeli Damla , Karacaoğlu Umut Mert , Pal Sujit , Türkmen Yunus Emre
Published: December 2024

Acenaphthylene-fused heteroarenes with a variety of five- and six-membered heterocycles such as thiophene, furan, benzofuran, pyrazole, pyridine and pyrimidine were synthesized via an efficient Pd-catalyzed reaction cascade in good to high yields (45–90%). This cascade involves an initial Suzuki–Miyaura cross-coupling reaction between 1,8-dihalonaphthalenes and heteroarylboronic acids or esters, followed by an intramolecular C–H arylation under the same conditions to yield the final heterocyclic fluoranthene analogues. The method was further employed to access polyoxygenated benzo[j]fluoranthenes, which are all structurally relevant to benzo[j]fluoranthene-based fungal natural products. The effectiveness of our strategy was demonstrated via a concise, four-step synthesis of the tetramethoxybenzo[j]fluoranthene derivative 18, which represents a formal total synthesis of the fungal natural product bulgarein.
The Impact of Service Quality, Facilities, and Location on Customer Satisfaction at PT Satya Trinadi Komira Perkasa in Tangerang Branch
Authors: Sutarjo Sutarjo , Utami Wanda Yulia , Ristanto Ristanto
Published: December 2024

This research examines the influence of service excellence, resource availability, and locational strategy on customer satisfaction at PT Satya Trinadi Komira Perkasa, with a primary focus on its Tangerang Regency branch. A descriptive approach was implemented, utilizing questionnaires as the primary tool for data gathering. The study involved 97 participants, selected using incidental sampling methods. Data analysis was performed through multiple linear regression, facilitated by SPSS 26 software. The results from partial testing indicate that service excellence and resource availability significantly enhance customer satisfaction, while locational strategy also holds considerable impact. Simultaneously, the findings from combined tests demonstrate that service excellence, resource availability, and locational strategy collectively have a profound effect on customer satisfaction, confirming Ha and rejecting Ho. The research emphasizes the pivotal role of service excellence in meeting and exceeding consumer expectations, fostering loyalty, and building a competitive edge. Adequate facilities and a strategically selected location complement service delivery, contributing to an improved customer experience. Businesses aiming to maintain market relevance must prioritize these factors. The study highlights the critical importance of aligning customer satisfaction strategies with operational efficiencies to secure sustainable growth.
Competitive Advantages of Small and Medium-sized Enterprises in the Field of Employment of the Population of Russia
Authors:   Central Russian Institute of Management – Branch of RANEPA, Parushina Natalya V. , Lytneva Natalya A. ,   Central Russian Institute of Management – Branch of RANEPA
Published: December 2024

The sphere of entrepreneurship during the pandemic and the introduction of sanctions suffered significantly; there was an outflow of personnel from business, which requires radical and effective work with personnel and employment in the labor market. The performance indicators of national projects and the work of government officials depend on the situation with employment in business, the creation of proper working conditions, increasing wages and attracting the population to entrepreneurship. The study made it possible to assess the state and trends in the development of entrepreneurship in the country, assess the competitive advantages of companies, and the employment situation. To conduct the research, methods of grouping, comparison, analysis, construction of time series, and methods of constructive discussion were used. As a result of analyzing data on the number of SMEs, the turnover of enterprises, employed workers, and wages, criteria were identified that provide competitive advantages to small and medium-sized businesses locally in terms of attractiveness for employment. The authors outline prospects for increasing the competitiveness of small and medium-sized businesses. The priorities of the formation and implementation of state policy are set, which should be aimed at improving the provisions of the national project in the field of development and support of SMEs. The increase in theoretical knowledge in the process of research is the development of scientific and methodological approaches to the analysis of the entrepreneurship market from the standpoint of assessing its competitiveness for the country’s economy. For practice, the significance of the study is that it allows us to formulate conclusions for improving the tools for supporting and developing SMEs in the future.
Competitiveness of University Graduates in the Labor Market
Authors:   Financial University under the Government of the Russian Federation, Pulyaeva Valentina N.
Published: December 2024

The problems of developing professional competencies, training, retraining and advanced training of personnel are currently quite acute in the labor market in the Russian Federation. The article is devoted to assessing the competitiveness of graduates of educational institutions of higher education by analyzing the correspondence of competencies that are formed as a result of mastering educational programs of higher education and the requirements of the labor market. This study seems relevant in connection with the need to determine the directions of transformation of the Russian higher education system, caused by the global challenges of recent years and the higher education reform planned in 2023 by the President of the Russian Federation. Any changes in the education system should ultimately lead to an increase in the demand for graduates and their competitiveness in the labor market. The author reviewed studies of the competencies of the future and the skills most in demand in the labor market, as a result of which the most relevant meta-skills that are in greatest demand among employers were identified, namely: effective communications, including in foreign languages, systems thinking, the ability to solve non-standard problems and adaptability. Using the example of professions in the economic and socio-humanitarian spheres, the author analyzed the requirements for applicants set out in vacancies on the hh.ru portal. The most key skills for a number of professions were identified, and they were compared with the competencies that must be mastered by students in accordance with the Federal State Educational Standards in these areas of bachelor’s degree training. As a result, competencies were identified that require addition to educational standards and educational programs of higher education. The results obtained can be used in the practical activities of educational organizations of higher education to improve the educational process and, as a result, increase the competitiveness of their graduates.
Economic Ideology of Sanction Policy: Fundamentals for Unfair Competition
Authors:   Lomonosov Moscow State University, Osipov Vladimir S.
Published: December 2024

More and more new restrictions are being introduced against the Russian Federation – sectoral and financial sanctions, personal restrictions, new packages of sanctions are being prepared. The article attempts to show the hidden goals of the sanctions policy through a political and economic analysis of the states that initiated the sanctions policy. The analysis proves that the purpose of the sanctions is not only to weaken the Russian Federation economically, but also to poor the allies of the United States, as the initiator of the sanctions, in full accordance with the sanctions paradox of D. Drezner. Protectionism as an economic policy has become entrenched in the actions of the American administration, which can be observed in the processes of deindustrialization of Germany and the weakening of the economy of the European Union countries as a whole. It is important to note that the debt strategy adopted by the American authorities as an element of economic policy has deep historical roots and was proposed by J. M. Keynes to overcome the economic consequences of the war. The inability or unwillingness to abandon the debt strategy, as well as the rapid reduction in the possibilities of using internal sources of economic growth, dictates to the United States the need to ensure external sources of economic growth, where the forceful elimination of a competitor (the Russian Federation) from the European markets of energy products, fertilizers, agricultural raw materials and metals becomes the tip of the iceberg of the ­US sanctions policy, however, the underwater part of the iceberg remained hidden. This article is devoted to its exposure. The theoretical significance of the research is the description of the interdependence of sanctions policy and protectionism policy.
Patterns of Development of Competitive Innovative Business Ecosystems: Dynamic Management Models
Authors:   V. I. Vernadsky Crimean Federal University, Kirilchuk Svetlana P. , Nalivaychenko Ekaterina V. ,   V. I. Vernadsky Crimean Federal University, Golovchanskaya Elena E. ,   V. I. Vernadsky Crimean Federal University, Cherniavaia Anna L. ,   V. I. Vernadsky Crimean Federal University, Murasov Suleyman D. ,   V. I. Vernadsky Crimean Federal University
Published: December 2024

The subject of the study is dynamic management models of innovative business ecosystems. The object of the study is the processes of development of business ecosystems at the macro level. The purpose of the study is to highlight the competitive advantages of dynamic management models in innovative economic systems. The main methods used in the study are: functional – to analyze the behavior of the economic system; grouping scientific knowledge – to systematize the patterns of development of economic systems; the system method was used to study the fundamental foundations of the theory of management models; methods of induction and deduction, as well as time series analysis were used to identify the competitive advantages of dynamic models of innovative business management-ecosystems and their practical implementation. The elements of the behavior of business ecosystems, the main groups of patterns of their development and management stages, approaches to building dynamic models are presented. The results can be useful in developing strategies for the development of innovative business ecosystems, as well as in building management models to achieve competitive advantages. Understanding the patterns of development of competitive innovative business ecosystems and the use of dynamic management models will help Russian companies to remain competitive and successful in the market.
Comunicación Asertiva en Estudiantes de Nuevo Ingreso a la Universidad
Authors: Aguirre Rodríguez Jaime , Ruiz Balderrama Linda Ventura , Burciaga Sánchez Brenda Guadalupe , Carmona García Laura Georgina
Published: December 2024

El cambio de la preparatoria a la universidad representa un evento significativo en la vida académica de los estudiantes. En este proceso, la comunicación asertiva emerge como una habilidad esencial para enfrentar los retos sociales y académicos. Objetivo: evaluar el nivel de comunicación asertiva de los estudiantes de nuevo ingreso a la Facultad de Contaduría y Administración (FCA) de la Universidad Autónoma de Chihuahua (UACH), enfocándose en habilidades comunicativas, empatía y regulación emocional. Metodología: La investigación se realizó en la ciudad de Chihuahua, en el periodo de agosto a noviembre del 2024; el enfoque de la investigación fue cuantitativo de tipo aplicada, en donde la población de interés fueron estudiantes de primer semestre de agosto a diciembre de 2024, se aplicaron encuestas a una muestra de 219 estudiantes. Resultados: dentro de los principales hallazgos se detectó la existencia de diferencias significativas en el nivel de asertividad. Conclusión: existe la necesidad de implementar programas de intervención educativa. Este trabajo se sustenta en estudios recientes sobre comunicación asertiva en el ámbito educativo.
Toma de Decisiones en la Atención de Enfermería en Servicios de Urgencia: Una Revisión Sistemática
Authors: Velasco Pillajo Karla Noemi , Ortega Tixi Kevin Armando , Cambizaca Mora Grace del Pilar
Published: December 2024

Los profesionales de enfermería en servicios de urgencias cumplen un papel crucial como primer punto de contacto clínico, donde su liderazgo y capacidad para tomar decisiones rápidas y precisas son esenciales para la atención efectiva del paciente. Esta revisión sistemática tuvo como objetivo evaluar la literatura científica existente sobre la toma de decisiones en la atención de enfermería en servicios de urgencia, identificando los factores determinantes que influyen en este proceso. Se realizó una búsqueda exhaustiva en cinco motores de búsqueda: PubMed, Google Académico, Scopus y SciELO, incluyendo estudios en inglés, español y portugués, publicados en los últimos cinco años. Los resultados revelaron que la experiencia clínica, la formación continua, la autonomía profesional, y el uso de tecnologías como los sistemas de alerta temprana son factores clave en la toma de decisiones en estos entornos. Además, el apoyo interdisciplinario, la gestión del estrés y la carga de trabajo, así como un entorno físico adecuado, también se identificaron como elementos críticos para la toma de decisiones informadas y seguras. La sistematización de estos factores, alineada con las recomendaciones de los autores revisados, sugiere que un enfoque integral es fundamental para mejorar la calidad de la atención en los servicios de urgencias.
Uso de Exoesqueleto en la Mano Derecha: Estudio Piloto
Authors: Cabrera González Felipe de Jesús , Hernández López Karina Itzel , Márquez Silva Salomé
Published: December 2024

Antecedente y objetivo: Las lesiones en la extremidad superior son un problema ocupacional en el ser humano, en donde la mano es de vital importancia para el desempeño en las actividades de la vida diaria. Con el objetivo de conocer las investigaciones realizadas de los exoesqueletos en rehabilitación de la mano, que contribuyan en su función de agarre. Material y Métodos: consistió en una revisión bibliográfica, consultando las principales bases de datos como: Dialnet, Redalyc, PubMed, Google Académico y Scielo; incluyendo en el artículo un total de 14 trabajos que abordan el tema, que muestran una metodología experimental y en estudio piloto. Resultados: el 57% de los trabajos arrojaron que el uso de exoesqueletos en la rehabilitación es efectivo para el abordaje terapéutico, en pacientes con secuela de evento cerebrovascular, en 2 artículos se menciona que no existen efectos adversos significativos en el aumento del dolor, por lo que se consideran una opción óptima para no alterar la frecuencia cardiaca o la fatiga muscular en pacientes con algún tipo de lesión neurológica u ortopédica. Conclusiones: Las investigaciones de los exoesqueletos evidencian los beneficios de sus funciones, con impacto en la recuperación de secuelas neurológicas y ortopédicas como coadyuvante en el tratamiento rehabilitador fisioterapéutico.
Los efectos subjetivos en el autismo a partir de la construcción del neoborde: Caso Nicola Cavernícola
Authors: Rendón Chasi Álvaro Andrés , Zambrano Torres Johanna Estefanía , Torres Gallardo Tatiana Aracely , Álvarez Chaca Carlota Carolina
Published: December 2024

El presente trabajo tuvo por objetivo analizar la importancia de la intervención psicológica orientada por el psicoanálisis lacaniano con sujetos autistas a partir de la construcción del neoborde mediante un estudio de caso. La metodología utilizada se consolidó en una investigación cualitativa, el método fue descriptivo y se utilizó el estudio de caso único en el que se realiza a partir de cuatro categorías de análisis clínico: neoborde, objeto autístico, doble y transferencia.  Para el desarrollo de los antecedentes y aportes se ha realizado una revisión bibliográfica a través de un recorrido teórico y clínico del psicoanálisis lacaniano que expone la posibilidad de una intervención desde la psicología clínica que produzca efectos subjetivos a partir de la construcción del neoborde, categoría clínica desarrollada por los psicoanalistas franceses Eric Laurent, Jean-Claude Maleval, Jacques-Alain Miller y otros. Los resultados del trabajo demuestran cómo la expansión y especialización de los objetos autísticos que conforman el neoborde hacen posible abrir y flexibilizar el vínculo social y su lugar en el mundo.
Las Nenis: Estrategias de Mercadotecnia en el Nano Emprendimiento Femenino Mexicano
Authors: Mendoza Guerrero Diana Laura , Alcántara Hernández Ruth Josefina , Vega Barrios Alejandra
Published: December 2024

El nano emprendimiento femenino, particularmente el fenómeno de las "NENIS" (Nuevas Emprendedoras de Negocios por Internet), representa una importante fuerza económica en México. Este estudio analiza, mediante una investigación aplicada, descriptiva y cuantitativa, las estrategias de mercadotecnia empleadas por nano emprendedoras en cuatro ciudades mexicanas (Guadalajara, Ciudad del Carmen, Saltillo y Pachuca). Se aplicó un cuestionario a 1,671 emprendedoras entre mayo 2023 y febrero 2024, examinando sus perfiles sociodemográficos y las estrategias de mercadotecnia que implementan. Los resultados revelan que la mayoría son mujeres entre 18 y 54 años (89.7%), con educación media superior o superior (66.12%), que contribuyen significativamente a la economía familiar (77.05%). Sus principales estrategias incluyen ventas por internet (35%), fijación de precios basada en costos (31%), y uso predominante de redes sociales para publicidad (37%). Los productos con mayor oferta son alimentos y bebidas (12.09%) y productos de higiene y salud (8.80%), mientras que en servicios destacan los de belleza (6.28%) y organización de eventos (5.92%). Este estudio contribuye a la comprensión del emprendimiento femenino digital en México y proporciona evidencia empírica sobre las estrategias de mercadotecnia más efectivas impulsando así al emprendimiento femenino y su capacidad de adaptarse al mercado para lograr el éxito empresarial.
Estrategias metodológicas en el proceso de inclusión de estudiantes con TDAH en una escuela pública de la ciudad de Loja, periodo 2024
Authors: Cárdenas Santín María Fernanda , Jaramillo Toledo Rosalia Yomaira , Cárdenas Palacios María Soledad , Llerena Samaniego JessicaVerónica , Muñoz Silva Efrain Fernando
Published: December 2024

El objetivo del estudio es analizar las estrategias metodológicas implementadas en el proceso de inclusión de estudiantes con Trastorno por Déficit de Atención e Hiperactividad en una escuela pública de la ciudad de Loja, con el fin de identificar fortalezas, debilidades y oportunidades de mejora que contribuyan a una educación inclusiva y de calidad. Es un estudio cualitativo descriptivo de corte transversal, se aplicó una entrevista semiestructurada a los maestros, que permitió conocer su percepción y conocimiento sobre la inclusión educativa, se utilizó la ficha de observación con la finalidad de determinar el comportamiento de los estudiantes. Los resultados reflejan una variabilidad significativa en los niveles de conocimiento y experiencia de los docentes respecto al TDAH. Si bien algunos tienen una comprensión básica centrada en los síntomas visibles, como la hiperactividad, la impulsividad y la inatención, otros demuestran un entendimiento más profundo, reconociendo los subtipos del trastorno y su impacto en el aprendizaje. En cuanto a la inclusión educativa, los docentes reconocen su importancia para garantizar equidad y derechos, mostrando compromiso por integrar a estos estudiantes en sus aulas. Sin embargo, destacan barreras como la falta de recursos, personal de apoyo y formación en estrategias inclusivas, por lo que existe una necesidad urgente de capacitación continua, recursos adecuados y un enfoque integral que promueva una educación inclusiva y de calidad.
Evaluación de la Calidad de Vida en Pacientes con Estadificación Temprana de la Enfermedad Renal Diabética Tipo 2
Authors: Flamenco Antonio Cesar Augusto , Chiñas Rojas Heriberto , Morales Bravo Sonia Julia
Published: December 2024

Introducción: la enfermedad renal diabética (ERD) es la principal causa de insuficiencia renal crónica terminal, con alta morbilidad y costos significativos. El cuestionario KDQOL-SF36 es una herramienta eficaz y económica para evaluar la calidad de vida relacionada con la salud (CVRS) en esta población. Objetivo: evaluar la calidad de vida en pacientes con estadificación temprana de ERD tipo 2. Métodos: estudio prospectivo, descriptivo y transversal realizado en el Hospital General de Zona No. 32 de enero a junio de 2023. incluyo 44 pacientes que cumplieron los criterios de inclusión, utilizando el cuestionario KDQOL-SF36. Para el análisis de datos se utilizó frecuencias simples, porcentaje, media y análisis de varianza. Resultados: media de edad 67.2 años, predominando mujeres (52.28%). Comorbilidades: hipertensión arterial (81.8%). La calidad de vida fue más baja en limitaciones de rol por problemas emocionales y físicos. Estadios avanzados mostraron menor funcionamiento físico (32.19) y percepción global de salud (25.77). ANOVA identificó diferencias significativas en satisfacción del paciente y dolor. Conclusión: La ERD afecta principalmente a mujeres mayores con comorbilidades. Se destacan variaciones en dominios críticos según el estadio KDIGO, es necesario intervenciones integrales para mejorar la calidad de vida y reducir la progresión de la enfermedad.
Molecular identification of SAP9, SAP10 genes with virulence factors and antifungal susceptibility profile among Candida species isolated from women with urinary tract infections
Authors:   Department of Biology, College of Science, University of Thi-Qar, Thi-Qar, Iraq, Jihad Muna F. , Salih Manal Badi ,   Department of Biology, College of Science, University of Thi-Qar, Thi-Qar, Iraq
Published: December 2024

Background. In recent years, there has been a rise in the occurrence of urinary tract infections (UTIs) caused by Candida pathogens. This increase is attributed to the growing resistance of these pathogens to antifungal drugs often used for their treatment. Many virulence factors encoded by virulent genes, which enable opportunistic Candida to invade host tissues and cause infection, for survey the existence of SAP9 andSAP10 genes with determine some virulence factors and antifungal susceptibility profiles among Candida species isolated from women suffering from urinary tract infections. Methods. For this investigation, urine specimens were gathered from female individuals residing in Thi-Qar Province, located in southern Iraq, over the period spanning from December 2022 to March 2023. The identification of all isolates was performed using several laboratory techniques, including assessment of colony characteristics on culture media, Gramme staining, germ tube formation, and analysis of morphological chromatic features on chromogenic agar. The identification was further validated using PCR analysis. All isolates were assessed for their production of extracellular secretory proteinase and hemolysin. Additionally, they were tested for antifungal activity using the disc diffusion method. The DNA was isolated, and the PCR technique was employed to identify the presence of virulence genes (SAP9 and SAP10). Results. A total of 50 Candida species isolates were collected from 150 urine samples. These isolates belonged to four different species within the Candida genus. The most found species was C. albicans, accounting for 54% of the isolates. This was followed by C. krusei at 24%, C. glabrata at 16%, and C. tropicalis at 6%. Proteinase activity was observed in 84% of Candida isolates. All Candida isolates exhibit positive hemolysin production with varying degrees of intensity. Among Candida species showed high resistance to Itraconazole (86%) and Clotrimazole (76%). The prevalence of SAP9 and SAP10 genes among Candida albicans was 62.69% and 100%, respectively. Conclusions. The present study highlights the prevalence of SAP genes and virulence factors with antifungal susceptibility which reflect high pathogenicity of Candida species.
A study of polymorphism and the serum level of Haptoglobin of people suffering from sickle cell disease and/or hepatitis C
Authors:   Department of Biology, College of Science, University of Thi-Qar, Thi-Qar, Iraq, Jumma Sally Salih , Maktoof Afrah Abid ,   College of Veternary Medicine, University of AL-shatrah, Thi-Qar, Iraq College of Science, University of Thi-Qar, Thi-Qar, Iraq, Nuhiar Rasha Salih ,   College of Veternary Medicine, University of AL-shatrah, Thi-Qar, Iraq College of Science, University of Thi-Qar, Thi-Qar, Iraq
Published: December 2024

Background. Haptoglobin is a type of alpha2 globulin found in human plasma. Its primary function is to bind to the globin portion of free hemoglobin in the bloodstream. Objectives. To examine the genetic polymorphism of the Haptoglobin (Hp) gene in patients diagnosed with sickle cell anemia, hepatitis C, and the co-occurrence of sickle cell anemia and hepatitis C . Patients and methods. A total of 130 participants were categorized into several groups: 40 patients with sickle cell anemia, 40 patients with hepatitis C, 10 patients with both sickle cell anemia and hepatitis C, and 40 individuals in the control group. The DNA was extracted and the polymerase chain reaction (PCR) was conducted using genotype-specific primers for the three areas of the haptoglobin gene. The genotypes were identified by running electrophoresis on agarose gels and calculating the proportion of each allele that was amplified. After obtaining the sequencing results of the haptoglobin gene and for the studied samples and for the three plots Hp2, Hp 1S and Hp 1F, Sequences for all three segments were registered in the NCBI Genome Bank for the first time locally and some were given independent accession numbers, and it will be considered a database for any future researcher working on the Hp genotypes in Iraq. Results. In Sickle cell Patient Hp1-1(0.13), Hp2-2(0.55), Hp2-1(0.32), Hepatitis-C Patient Hp1-1(0.13), Hp2-2(0.63), Hp2-1(0.24), Sickle cell with Hepatitis C Patient Hp1-1(0.20), Hp2-2(0.60), Hp2-1(0.20), and Control group Hp1-1 (0.30), Hp2-2 (0.50), Hp2-1 (0.20). Hp2-2 was the most common phenotype across all categories, The T allele and TT genotype seem more visible in sickle cell anemia and hepatitis diseases than the AA genotypes of Hp-2 643 T>, and no correlation between patients and health control group with Hp1S gene. Also, the present study reports that there is no correlation between patients of sickle cell anemia and health control group with Hp-1F 867 G > A gene, but the G allele and GG genotype more visible in hepatitis diseases than the AA genotypes of Hp-1F 867 G > A gene. Conclusions. The Hp2-2 haptoglobin phenotype was the most common among patients. Different groups may have an influence on the development of sickle cell anemia and hepatitis C.
An association study of serum calcium as a predictor of severity and prognosis in diabetic ketoacidosis in a tertiary care hospital
Authors:   Department of General Medicine, Saveetha medical college, Saveetha Nagar, Thandalam, Chennai, India, Koduri Amukthamalyada , Kakumani Jagadeswar ,   Department of General Medicine, Saveetha medical college, Saveetha Nagar, Thandalam, Chennai, India, Bathena Arun Kumar ,   Department of General Medicine, Saveetha medical college, Saveetha Nagar, Thandalam, Chennai, India, Kumar S. Magesh ,   Department of General Medicine, Saveetha medical college, Saveetha Nagar, Thandalam, Chennai, India
Published: December 2024

Background and objectives. Diabetic ketoacidosis (DKA) is a severe complication of diabetes mellitus characterized by metabolic acidosis and elevated ketone levels. While serum calcium levels have been studied in various medical contexts, their significance in assessing the severity and prognosis of DKA remains insufficiently examined. This study aims to explore the relationship between serum calcium levels and the clinical outcomes of DKA patients in a tertiary care setting. Materials and methods. We conducted a retrospective cohort study involving 20 patients hospitalized with DKA. Clinical data and laboratory results, including initial serum calcium concentrations, were gathered for analysis. Patients were categorized based on their serum calcium levels, and the relationship between these levels and clinical outcomes, severity indicators, and duration of hospital stay was evaluated. Outcomes. The primary results reveal a notable association between admission serum calcium levels and the severity of DKA. Patients with lower initial calcium levels experienced more complications, extended hospital stays, and higher severity indicators. Additionally, the study suggests potential links between serum calcium and important factors related to DKA severity. Conclusion. This research highlights the possible role of serum calcium as a predictor of severity and prognosis in DKA. Recognizing the connection between serum calcium levels and clinical outcomes may enhance risk assessment, facilitate early interventions, and support customized management approaches. Further prospective studies are necessary to confirm these findings and investigate the underlying mechanisms at play.
The role of SNP (rs11908352) genetic polymorphisms on serum level of matrix metalloproteinase-9 in rheumatoid arthritis
Authors:   Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq, Al-Nuaimy Wafaa Ayad , Salloom Dunya Fareed ,   Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq
Published: December 2024

Background. MMP-9 plays a significant role in the destruction of the extracellular matrix (ECM) in various physiological and pathological processes, including tissue remodeling. MMP-9 is elevated in pathologies involving abnormal immune responses. The extent of joint damage varies significantly among individuals with rheumatoid arthritis (RA), and much of its genetic inheritance remains unexplained. Multiple autoimmune diseases share common genetic risk factors that may also influence disease progression. Genetic variants in MMP-9 could potentially affect its transcriptional expression or enzymatic activity. Objective. To evaluate the impact of serum MMP-9 levels and the SNP (rs11908352) in a group of patients with rheumatoid arthritis compared to a control group. Methods. Seventy-three RA patients with a mean age of 47.91 ± 1.44 years were included in this study, compared to sixty-eight healthy controls matched in age and gender, with a mean age of 46.42 ± 1.51 years. Serum levels of MMP-9 and rs11908352 SNPs were examined in individuals with RA and compared to the control group. Results. The findings revealed a notable increase in MMP-9 levels in RA patients compared to healthy controls (1.85 ± 0.12 vs. 1.31 ± 0.10). Additionally, rs11908352 SNP analysis showed a statistically insignificant rise in the frequency of the AA genotype and A allele in the patient group compared to controls (24.66% vs. 16.18%; p = 0.297; OR = 1.70) and (51.0% vs. 44.0%; p = 0.285; OR = 1.30), respectively. Genotype frequencies CA, CC, and allele frequency C showed nonsignificant decreases in RA patients compared to controls (52.05% vs. 55.88%; p = 0.736; OR = 0.86), (23.29% vs. 27.94%; p = 0.566; OR = 0.78), and (49.0% vs. 56.0%; p = 0.285; OR = 0.77), respectively. Patients with the AA genotype exhibited markedly elevated serum MMP-9 levels compared to the control group (p = 0.007). Conclusion. The results of this study demonstrated a significant correlation between serum MMP-9 levels and rs11908352 genetic variation in RA patients, suggesting that specific genetic regions associated with autoimmune diseases may influence the severity of joint damage in rheumatoid arthritis.
Comment on “How might China-US industrial policies affect the Philippines?: a quantitative exercise”
Authors: Varela Gonzalo
Published: December 2024

n.a.
Comment on “Industrial policy for innovation: why does it matter?”
Authors: de Dios Emmanuel
Published: December 2024

n.a.
Öğretmenlerin Çevresel Gürültüye Maruz Kalmasına Yönelik Örnek Bir Saha Çalışması
Authors: Taşkinoğlu Onur , Armağan Bülent
Published: December 2024

Gürültü insanların sağlığını, verimliliğini ve yaşam kalitesini etkileyen önemli unsurlardan biridir. Gürültü insanın zihnini meşgul eden çözümlenmesi gerekli bir sorundur. Çevresel gürültü yapım, ulaşım, inşaat ve eğlence gürültü kaynaklarından çevreye yayılan gürültüdür. Çevresel gürültü kaynakları içerisinde yer alan ulaşımın gürültüye çok büyük etkisi vardır. Şehir yaşamında en yaygın ve rahatsız edici kirlilik türlerinden biridir. Ulaşım denildiğinde, karayolu, raylı sistemler ve hava alanları akla gelmelidir. Karayolu gürültüsü, lastik ile yol arasındaki sürtünme, araç motorlarının sesleri ve egzozlarından, raylı sistemlerdeki gürültü, trenlerin ray üzerindeki geçişleri sırasındaki tekerlek ile ray arasındaki seslerden, havalimanlarındaki gürültü uçakların inişi ve kalkışı sırasında çıkardığı seslerden kaynaklanmaktadır. Çevresel gürültü kaynaklarına olan mesafe azaldıkça gürültün etkisi artmaktadır. Çevresel gürültü, çalışanlarda, dikkat dağınıklığı, yaptığı işe odaklanamama, iş verimliliğinde düşüş ve stres gibi olumsuz etkilere neden olabilmektedir. Bu makale ile öğretmenlerin maruz kalabileceği çevresel gürültü üzerine bir çalışma gerçekleştirilmiştir. İstanbul da Fatih ilçesinde dört lise seçilmiş olup, bu liselerde gürültü ölçümleri yapılmış ve anketler uygulanmıştır. Yapılan gürültü ölçümleri, liselerin sınıflarında pencere açık ve kapalı konumda olacak şekilde gerçekleştirilmiştir. Ölçümlerde 36,6 dBA ile 63,1 dBA aralığında gürültü sonuçları elde edilmiştir. Anketler kullanılarak öğretmenlerin gürültü algıları ölçülmüş, ölçümle anketin birbirini tutup tutmadığı değerlendirilmiştir. Gerek çevresel gürültü ölçümleri, gerekse anketler neticesinde çevresel gürültünün ez düşük olduğu liselerde genel olarak memnuniyetin yüksek olduğu ortaya konulmuştur. Okullarda iş güvenliği uzmanlarının çevresel gürültü konusunda dikkat etmesi gereken hususlar belirtilerek, yapılabilecek basit öneriler sıralanmıştır.
Characterizing Superflares in HR 1099 Using Temporal and Spectral Analysis of XMM-Newton Observations
Authors: Didel Shweta , Pandey Jeewan C. , Srivastava A.K.
Published: December 2024

In the present paper, we analyze three energetic X-ray flares from the active RS CVn binary HR 1099 using data obtained from XMM-Newton. The flare duration ranges from 2.8 to 4.1 hr, with e-folding rise and decay times in the range of 27–38 minutes and 1.3–2.4 hr, respectively, indicating rapid rise and slower decay phases. The flare frequency for HR 1099 is one flare per rotation period. Time-resolved spectroscopy reveals peak flare temperatures of 39.44, 35.96, and 32.48 MK, emission measures of 7 × 1053–8 × 1054 cm−3, global abundances of 0.250, 0.299, and 0.362 Z
⊙, and peak X-ray luminosities of 1031.21−32.29 erg s−1. The quiescent state is modeled with a three-temperature plasma maintained at 3.02, 6.96, and 12.53 MK. Elemental abundances during quiescent and flaring states exhibit the inverse-first ionization potential (i-FIP) effect. We have conducted a comparative analysis of coronal abundances with previous studies and found evidence supporting the i-FIP effect. The derived flare semi-loop lengths of 6–8.9 × 1010 cm were found to be comparable to the other flares detected on HR 1099; however, they are significantly larger than typical solar flare loops. The estimated flare energies, ranging from 1035.83−37.03 erg, classify these flares as super-flares. The magnetic field strengths of the loops are found to be in the range of 350–450 G. We diagnose the physical conditions of the flaring corona in HR 1099 through the observations of superflares and provide inference on the plasma processes.
SOFIA/HAWC+ Far-infrared Polarimetric Large-area CMZ Exploration Survey. IV. Relative Magnetic Field Orientation throughout the CMZ
Authors: Paré Dylan M. , Chuss David T. , Karpovich Kaitlyn , Butterfield Natalie O. , Iuliano Jeffrey Inara , Pan Xing , Wollack Edward J. , Zhang Qizhou , Morris Mark R. , Nilsson Mathilda , Zhao Roy J.
Published: December 2024

The nature of the magnetic field structure throughout the Galactic Center (GC) has long been of interest. The recent Far-InfraREd Polarimetric Large-Area Central Molecular Zone (CMZ) Exploration (FIREPLACE) Survey reveals preliminary connections between the seemingly distinct vertical and horizontal magnetic field distributions previously observed in the GC. We use the statistical techniques of the Histogram of Relative Orientation and the Projected Rayleigh Statistic to assess whether the CMZ magnetic field preferentially aligns with the structure of the CMZ molecular clouds or the morphology of the nonthermal emission of the GC nonthermal filament (NTF) population. We find that there is a range of magnetic field orientations throughout the population of CMZ molecular clouds, ranging from parallel to perpendicular orientation. We posit these orientations depend on the prevalence of gravitational shear in the GC, in contrast with what is observed in Galactic Disk star-forming regions. We also compare the magnetic field orientation from dust polarimetry with individual prominent NTFs, finding a preferred perpendicular relative orientation. This perpendicular orientation indicates that the vertical field component found in the FIREPLACE observations is not spatially confined to the NTFs, providing evidence for a more pervasive vertical field in the GC. From dynamical arguments, we estimate an upper limit on the magnetic field strength for this vertical field, finding B ≤ 4 mG. A field close to this upper limit would indicate that the NTFs are not local enhancements of a weaker background field and that the locations of the NTFs depend on proximity to sites of cosmic-ray production.
Stability of f(Q, B) Gravity via Dynamical System Approach: A Comprehensive Bayesian Statistical Analysis
Authors: Lohakare Santosh V. , Mishra B.
Published: December 2024

In this work, we explore the cosmological stability of f(Q, B) gravity using a dynamical system approach, where Q denotes the nonmetricity scalar and B represents the boundary term. We determine the model parameters of f(Q, B) through Bayesian statistical analysis, employing Markov Chain Monte Carlo techniques. This analysis incorporates numerical solutions and observational data from cosmic chronometers, the extended Pantheon+ data set, and baryonic acoustic oscillation measurements. Our findings reveal a stable critical point within the dynamical system of the model, corresponding to the de Sitter phase, which is consistent with current observations of the Universe dominated by dark energy and undergoing late-time accelerated expansion. Additionally, we utilize center manifold theory to examine the stability of this critical point, providing deeper insights into the behavior of the model. The cosmological implications of f(Q, B) gravity indicate a smooth transition in the deceleration parameters from deceleration to the acceleration phase, underscoring the potential of the model to describe the evolution of the Universe. Our results suggests that the f(Q, B) model presents a viable alternative to the standard ΛCDM model, effectively capturing the observed acceleration of the Universe and offering a robust framework for explaining the dynamics of cosmic expansion.
A Natural Laboratory for Astrochemistry: The Variable Protostar B335
Authors: Lee Jeong-Eun , Evans Neal J. , Baek Giseon , Kim Chul-Hwan , Noh Jinyoung , Yang Yao-Lun
Published: December 2024

Emission lines from complex organic molecules in B335 were observed in four epochs, spanning a luminosity burst of about 10 yr duration. The emission lines increased dramatically in intensity as the luminosity increased, but they have decreased only slightly as the luminosity has decreased. This behavior agrees with expectations of rapid sublimation as the dust temperature increases, and of slower freeze-out after the dust temperature drops. Further monitoring of this source, along with detailed chemical models, will exploit this natural laboratory for astrochemistry.
Introduzione
Authors: De Leo Maya
Published: December 2024

L’introduzione ripercorre brevemente le tappe principali della produzione storiografica relativa ai temi LGBTQIA+ e colloca gli articoli all’interno del dibattito storiografico internazionale, di cui sono descritti sinteticamente i nodi teorici principali.
“Coming to power”. Appunti per una storia della sottocultura S/M nei movimenti lesbici e omosessuali
Authors: Niri Virginia
Published: December 2024

L’articolo indaga in che modo le pratiche sessuali sadomasochiste siano state inserite in un pensiero politico e di comunità nei movimenti lesbici e omosessuali degli anni “Settanta” in Italia e negli Stati Uniti. Tema della ricerca è in particolare il nodo del potere e della sua elaborazione teorica, con riferimento alle pratiche femministe autocoscienziali e all’esplorazione di nuovi standard sessuali ed emozionali: in che modo dialogano con il sadomasochismo? Come sono accolte le pratiche SM? È davvero possibile parlare di «SM communities»?
San Basilio, storie de Roma: sceneggiatura di una borgata attrice della propria storia
Authors: Laruffa Alessandro
Published: December 2024

Tra il 2014 ed il 2017 un gruppo composto da membri dell’associazionismo, attivisti ed abitanti del quartiere San Basilio, quadrante nord-est di Roma, dà vita al progetto di public history San Basilio, storie de Roma, con l’obiettivo di ricostruire la storia della borgata attraverso un processo partecipato con la comunità locale. Nell’ambito delle attività progettuali viene prodotto un video-documentario che prende le mosse dalle origini della borgata negli anni Trenta sino all’attualità. Il contributo si propone di analizzare il progetto ed il documentario alla luce degli obiettivi prefissati, dell’approccio storiografico e dei risultati ottenuti. Quali valori aggiunti e criticità nel rendere una comunità locale “attrice” della propria storia?
Enormities of Early Marriages of Girls Lensing Physical-Mental Health Impairments
Authors: Singh Bhupinder
Published: December 2024

Early marriages have long been a source of worry because of the possible negative impacts on one's physical and mental health, especially when they involve females. Child marriage continues to be a common practice in many places, affecting millions of girls globally, despite global attempts to abolish it. Gender inequality, socioeconomic circumstances and cultural expectations are some of the main causes of early marriages. The physiological immaturity of young brides poses risks during pregnancy and childbirth, leading to higher rates of maternal and infant mortality. Legislation and enforcement play a pivotal role in preventing and combating child marriages. This chapter explores existing legal frameworks globally and highlights the importance of stringent laws, effective implementation and awareness campaigns to curb this harmful practice via- Policy Recommendations; Education and Awareness: Support Systems; Community Engagement because early marriages can have profound effects on the physical health of girls.