bluuebunny/crossref_metadata_2025 huggingface dataset:
Occlusion-Robust Online Multi-Object Visual Tracking using a GM-PHD Filter with CNN-Based Re-Identification
Authors: Baisa Nathanael L.
Published: April 2022

We propose a novel online multi-object visual tracker using a Gaussian mixture Probability Hypothesis Density (GM-PHD) filter and deep appearance learning. The GM-PHD filter has a linear complexity with the number of objects and observations while estimating the states and cardinality of time-varying number of objects, however, it is susceptible to miss-detections and does not include the identity of objects. We use visual-spatio-temporal information obtained from object bounding boxes and deeply learned appearance representations to perform estimates-to-tracks data association for target labeling as well as formulate an augmented likelihood and then integrate into the update step of the GM-PHD filter. We also employ additional unassigned tracks prediction after the data association step to overcome the susceptibility of the GM-PHD filter towards miss-detections caused by occlusion. Extensive evaluations on MOT16, MOT17 and HiEve benchmark datasets show that our tracker significantly outperforms several state-of-the-art trackers in terms of tracking accuracy and identification.
Tác động của con người lên sinh vật biển
Authors: Hanh Ha Thi Hong
Published: April 2022

Tác động của con người lên sinh vật biển
Leading counterterrorism organizations need to take action now
Authors: Quang-Loc Nguyen
Published: April 2022

How to sustain the international relations?
HUBUNGAN DAN PEMBAGIAN KERJA DALAM PENGELOLAAN KOPERASI
Authors: N andhini putri
Published: April 2022

masyarakat merupakan sebua oerganisasi yang merupakan kumpulan dari sejumlah individu memiliki visi dan misi yang sama dalam kehidupan
ANALISIS PENDAPATAN NASIONAL DALAM ISLAM
Authors: Sugiatni Evi
Published: April 2022

Pendapatan nasional merupakan salah satu bentuk alat yang digunakan untuk menetapkan tingkat perekonomian yang ada di dalam suatu negara. Dan perhitungan yang ada di dalam pendapatan nasional bertujuan untuk mendapatkan sebuah gambaran yang berkaitan tingkat pertumbuhan ekonomi yang sudah di peroleh dalam suatu negara. Pendapatan nasional ini dapat hitung apabila kita telah mengetahui nilai dari beberapa unsur yang ada di dalam negara, salah satu unsur itu adalah GDP ( Gross Domestic Product ). Adapun beberapa instrumen atau alat yang digunakan dalam menghitung pendapatan nasional yaitu seperti zakat, Infaq Zadaqah, waqaf, dan Pay. Instrumen inilah yang perluh kita ketahui lebih dahulu di dalam pembahasan pendapatan nasional terutama pada pembahasan pendapatan nasinal secara syariah atau no-Konvensional..
ANALISIS PENDAPATAN NASIONAL DALAM EKONOMI ISLAM
Authors: Rasti Ardina
Published: April 2022

pendapatan nasional dapat diartikan sebagai jumlah barang dan jasa yang dihasilkan suatu negara pada periode tertentu biasanya satu tahun.
A New Online Assessment of Cognitive Functions: Problem Solving, Executive Functions and Academic Outcomes in Primary School
Authors: Berg Valeska , Rogers Shane L. , McMahon Mark , Garrett Michael , Manley Dominic
Published: April 2022

Problem solving is a critical skill for life and academic success. The identification of problem solving skills early in life requires appropriate assessment tools. However, to date well-structured problem solving tasks that children can both engage with and enjoy are lacking. This study reports on the evaluation of one such task (eFun Castle Adventure) developed as part of a research project that investigated related cognitive constructs (executive functions), a traditional problem solving task (Tower of Hanoi), and academic outcomes. A sample of 260 students aged 6-9 from three primary schools was tested on two problem solving tasks and three executive functions tasks (working memory, inhibition, and cognitive flexibility). Additionally, enjoyment rating with the problem solving tasks and grades were examined. The results showed that students enjoyed playing the new problem solving task more than the traditional task. Furthermore, we found moderate associations between the two problem solving tasks, low intercorrelations with executive function tasks, and low to medium correlations between executive functions and problem solving. Executive functions are related to and predict academic outcomes, whereas the relationship between well-structured problem solving and academic outcomes is less clear and needs further research. The new eFun problem solving and executive function tasks were found to be promising new measures to assess cognitive functions in an easy, accessible, and secure way in the classroom.
Development and Validation of the Climate Capability Scale
Authors: Horry Ruth , Rudd Jennifer , Skains R. Lyle , Ross Helen
Published: April 2022

Climate change poses a serious existential threat to life on our planet. If we are to mitigate against the most damaging impacts of climate change, we need citizens who are willing and able to make changes to their individual behaviours, but who are also politically engaged and motivated to advocate for systemic change; we need citizens who are Climate Capable. Across four studies with 849 adult and 458 adolescent participants (aged 12-15), we developed and validated a 24-item Climate Capability Scale. We demonstrate that the scale is internally consistent, has good test-retest reliability, correlates with measures of related constructs such as environmental worldview and scientific literacy, and predicts self-reported pro-environmental behaviour. The Climate Capability Scale may have particular value in educational and public engagement contexts for measuring the effectiveness of programs and interventions designed to increase Climate Capability.
A General Cognitive Ability Factor for the UK Biobank
Authors: Williams Camille , Labouret Ghislaine , Wolfram Tobias , Peyre Hugo , Ramus Franck
Published: April 2022

UK Biobank participants do not have a high-quality measure of intelligence or polygenic scores of intelligence to simultaneously examine the genetic and neural underpinnings of intelligence.We created a standardized measure of general intelligence (g) relative to the UK population and estimated its quality. After running a GWAS of g on UK Biobank participants with a g of good quality and without neuroimaging data (N = 187,288), we derived a g polygenic score for UK Biobank participants with neuroimaging data.The g factor from eight cognitive tests for individuals with at least one test (N = 501,650) explained 29% of the variance in cognitive test performance. The polygenic score for British individuals with neuroimaging data (N = 27,174) explained 7.6% of the variance in g.We provided high-quality g factor estimates for most UK Biobank participants and g factor polygenic scores for UK Biobank participants with neuroimaging data.
Polish Adaptation of the Igroup Presence Questionnaire
Authors: Strojny Pawel , Lipp Natalia , Strojny Agnieszka
Published: April 2022

The importance of presence is growing along with the research on virtual environments. Measuring sense of presence may be crucial not only for designing better software, but also because a high presence level can determine other desired features such as transfer of skills with professional simulators. The authors conducted a translation and study that aimed to provide a Polish version of the Igroup Presence Questionnaire (IPQ-PL). The questionnaire was completed by 245 participants. Confirmatory factor analysis was used to test two models – a three factor structure and a bifactor model with orthogonal rotation. Both models have satisfactory fit. The internal consistency of the scale is high and its external validity is satisfying. The obtained results indicate that the proposed Polish version of the IPQ is a valid tool for measuring the presence in virtual environments. Thus, it may be used in studies related to presence conducted on Polish samples.
Attentional Switch to Memory: An early and critical phase of the cognitive cascade allowing autobiographical memory retrieval
Authors: Servais Anaïs , Christophe Hurter , Barbeau Emmanuel
Published: April 2022

Remembering and mentally reliving yesterday’s lunch is a typical example of episodic autobiographical memory retrieval. In the present review, we reappraised the complex cascade of cognitive processes involved in memory retrieval, by highlighting one particular phase that has received little interest so far: attentional switch to memory (AStoM). As attention cannot be simultaneously directed toward external stimuli and internal memories, there has to be an attentional switch from the external to the internal world in order to initiate memory retrieval. We formulated hypotheses and developed hypothetical models of both the cognitive and brain processes that accompany AStoM. We suggest that gaze aversion could serve as an objective temporal marker of the point at which people switch their attention to memory, and discuss the possibility of identifying a similar EEG marker. We also highlight several fields (neuropsychology, neuroscience, social cognition, comparative psychology, human-machine interfaces, robot interactions) in which AStoM markers could be essential. Our review thus provides a new framework for understanding memory retrieval.
Mixed-heritage Individuals and Systemic Risk During Negotiation of Identity
Authors: Tsai Aurora , Straka Brenda , Kimura Daisuke
Published: April 2022

Poststructuralist research in language and identity demonstrate how individuals exert agency to enact alternative identities, reshape power structures, and gain access to resources (e.g., Darvin & Norton, 2015). However, this approach to agency carries immense risk for minoritized individuals, who must regularly negotiate their identities under systemic racism and linguistic discrimination. We focus on mixed-heritage individuals (MHIs), who are regularly questioned or denied their ethnoracial identities through everyday microaggressions (Nadal et al., 2011) and examine 293 MHIs’ responses to open-ended survey questions, describing the strategies they use and risks experienced during negotiation of identity. Findings reveal MHIs use explanations, cultural capital, and linguistic styling to express ethnoracial identities; however, experiences of denial, objectification, racial imposter syndrome, and anxiety lead many to assess which situations are safe to enact their identities and which are not. Consequently, we discuss the importance of recognizing systemic risk during negotiation of identity for racialized individuals.
Structural violence and physical death at Tlatelolco: selecting the chronically malnourished for sacrifice at a Late Postclassic Mesoamerican city (1300-1521 CE)
Authors: Blevins Kelly Elaine , McGrane Madeline , Lory Josefina Mansilla , Arroyo Salvador Guilliem , Buikstra Jane E.
Published: April 2022

Human sacrifice in Mesoamerican cities was diverse, highly ritualized, and remains incompletely characterized. Knowing who was selected for ritual violence is essential for interpreting specialized mortuary deposits and furthering research on Mexica society. To understand the structure and variability of sacrificial and mortuary practices, we examine here three burial contexts from Tlatelolco, a densely populated city in the heart of the Triple Alliance. The interment contexts of Paso a Desnivel (n=45) and Grupo Norte (n=52) had been excavated from within the ceremonial center near the Tlatelolco Templo Mayor, and Atenantitech (n=40) from a bordering calpulli or neighborhood. To establish which contexts are likely sacrificial deposits, we compare the age-at-death distributions, biological sex, and perimortem ritual trauma across these sites. We seek to understand if social status determined sacrificial inclusion by using metabolic and infectious disease as proxies for resource inequality. We find that the residential deposit approximates an attritional mortality distribution and that ceremonial center deposits primarily comprised non-adults, who also presented with significantly higher rates of metabolic and infectious disease than the non-adults from the residential site. Informed by previous studies and the ethnohistorical literature, we propose that impoverished individuals living on the margins Mexica society were chosen as sacrificial victims. High prevalence of metabolic and infectious disease co-morbidity indicate that these individuals endured long-term nutritional deficiency, apparently vitamin C. Further, variation in age, pathology, and perimortem treatment among ceremonial center deposits reveal the striking diversity of ritualized killings in a prominent Mexica city.
Concordance of self-reported sexual intercourse frequency between members of mixed-sex couples attempting conception
Authors: Bond Julia C. , Geller Ruth J. , White Katharine O. , Hatch Elizabeth E. , Rothman Kenneth J. , Wise Lauren A.
Published: April 2022

Studies about sexual health require accurate information on sexual behaviours, yet there is no gold standard for assessing sexual behaviour. Concordance of partner reports is one way to estimate the reliability and, indirectly, the validity of such data. We aimed to evaluate the inter-partner concordance of self-reported intercourse frequency among mixed-sex couples attempting conception. We analyzed data from Pregnancy Study Online (PRESTO), a North American prospective preconception cohort study. During 2013–2021, self-reported intercourse frequency at baseline was ascertained using the same question for both partners: “In the past month, about how often did you have sexual intercourse with your partner?” with categorical response options. We used unweighted and linear-weight weighted kappas to assess inter-partner concordance of reported intercourse frequency and log-binomial regression to estimate unadjusted and adjusted prevalence ratios (PR) and 95% confidence intervals (CI) for predictors of discordance. Among 3,015 couples, 1,927 (63.9%) reported exactly concordant categories of intercourse frequency, while the female partner reported more frequent intercourse in 715 (23.7%) couples and the male partner reported more frequent intercourse in 373 (12.4%) couples. Unweighted and weighted kappas were 0.50 (95% CI 0.48, 0.53) and 0.63 (95% CI 0.61, 0.65), respectively. Predictors of discordance included marital status (unmarried versus married: PR = 1.61 [95% CI 1.11, 2.29] for the male partner reporting more frequent intercourse) and longer relationship length (5–9 years, PR = 1.14 [95% CI 0.96, 1.34]; ≥ 10 years, PR = 1.14 [95% CI 0.92, 1.42], respectively, compared with < 5 years) for the female partner reporting more frequent intercourse.
Ethnocultural Approach to the Formation of Musical and Pedagogical Repertoire on the Example of Vocal Lyrics of Chuvash Composers
Authors: Agakova Alisa Leonidovna
Published: April 2022

The purpose of the article is to substantiate the ethno-cultural approach to the formation of the musical and pedagogical repertoire of students of the Chuvash State Institute of Culture and Arts. The implementation of the ethno-cultural approach ensures the orientation of their professional training to the development of culture as a historically determined type of human activity with certain ethnic characteristics. The author examines the potential of Chuvash vocal lyrics in the aspect of an ethnocultural approach, for which he analyzes romance in detail as a genre of Chuvash composer music. Based on the method of stylistic analysis, conclusions are drawn about the derivative character of the Chuvash romance, which goes back through the Russian medium to the medieval European musical tradition. The first Chuvash romances were vocal works based on the words of the classics of Russian literature A. Pushkin and M. Lermontov translated into the Chuvash language. Subsequently, independent Chuvash works with an ethnic sound appeared in the Chuvash musical art (works by O. Agakova, Y. Grigoriev). Romances have enriched Chuvash chamber music with vivid artistic images, they are characterized by a deep insight into the drama of verse, sincerity, lyricism and nobility of utterance, a variety of forms. The musical and pedagogical repertoire of vocal students should be supplemented with works of both the early stage (romances to the words of Pushkin and Lermontov translated into Chuvash) and modern (romances with ethnic sounding accompaniment with a characteristic Chuvash folk music mode and metrorhythmics, with Russian and Chuvash texts).
Training students of the College of Culture for a stage performance of the Chuvash folk dance
Authors: Nyanina Liudmila Nikolaevna
Published: April 2022

Folk dance is an important tool in preparing students of the College of Culture for teaching as leaders of an amateur creative team. The content of their training includes the choreographic creativity of different peoples. The purpose of the article is to determine the necessary and sufficient minimum knowledge about the specific features of the Chuvash national choreography so that students can use this knowledge to implement choreographic productions, improve performing techniques and embody the manner of performing the Chuvash folk dance. The material of the research was the author's long-term observations of the Chuvash folk choreography, passed through personal experience of staging dances for the professional stage. The work is based on the description method and in general is of a review nature. Folk dance is the most expressive layer of the Chuvash culture. It contains a significant potential necessary to maintain the vital properties of the Chuvash ethnos. In particular, it has unique ethnic features and only in some cases allows borrowing from other peoples. In general, the Chuvash dance in movements repeats the aesthetics of national embroidery. Important properties in the Chuvash dance are endowed with hands: women's movements are extremely smooth and slow, men's are sharp and fast. The position of the hands, combined with the movement of the legs and the body as a whole, create a unique ethnic flavor. Chuvash dances have dialectal differences according to ethnographic groups, while they are based on a single complex, historically dating back to rituals and ceremonies.
On the Problem of Rational Use of the Potential of the Natural and Cultural Heritage of the Crimea: Features of Development Based on the Concept of a Unique Historical Territory
Authors: Nikolaenko Nikolay Vasilevich
Published: April 2022

The article is devoted to the problem of rational use of the potential of natural and cultural heritage objects. The relevance of the article is due to the fact that the development of Crimean tourism and local history organizations urgently requires practical measures to modernize socio- and ethno-cultural activities, and also leads to the search for new forms of interaction with local museums and the development of innovative methods and principles of preserving cultural and historical heritage. The author of the article considers the ecomuseum project "Belbek Valley" as an opportunity to reconstruct the appearance of rural dwellings of the 8-9 centuries. He raises the question of the materialization of such a reconstruction, the creation of a museum complex that will clearly present an early medieval rural settlement. The purpose of the article is to give an idea of the initial stage of design, i.e. the identification of the main objects of the prospective territory of the Crimea, followed by the development of a comprehensive program for the development of the region on the principles of the concept of unique historical territories. The materials for the study were natural monuments, archaeological sites, medieval historical and cultural memorials of the Crimean Peninsula. Based on the method of theoretical analysis, the uniqueness of the ecomuseum project "Belbek Valley" was substantiated. The conclusion of the article is made about the mountainous southwestern part of the Crimean Peninsula as a unique territory, which is a holistic, dispersed museum, full of monuments of nature, history, and culture.
Эколого-ценотический и флористический анализ популяций Dactylorhiza fuchsii (Druce) Soo в Казахстанской части Алтайской горной страны
Authors: Сумбембаев А.А. , Данилова А.Н. , Премина Н.В. , Матвеева Е.В.
Published: April 2022

Целью статьи явилось определение экологического оптимума и пластичности вида в обследованных сообществах на основе сходства и различия фитоценозов. Материалы получены в результате обследо-вания территории маршрутно-рекогносцировочным методом. На основании полевых исследований в обследуемом регионе выделено четыре основные популяции, отмечено 12 местонахождений. Установлено, что ценофлора популяций D. fuchsia в Казахстанской части Алтайской горной страны сформирована 251 видом, относящимся к 49 семействам, 155 родам. Характерными видами-маркерами являются Betula verrucosa, Juncus compressus, Poa palustris, Poa pratensis, Filipendula ulmaria, Geum rivale, Sanguisorba officinalis. Ценоэкотипы занимают влажные луговины, опушки березовых и смешанных лесов, долины рек и ручьев с неоднородным увлажнением и богатым гумусным субстратом. Флоропопуляционное сходство обследованных популяций варьирует в пределах 12–24 %. В экологическом отношении во всех популяциях основу фитоценозов составляют мезофиты — 74 %, доля мезогигрофитов — 18, ксеромезофитов — 8 %. В составе жизненных форм доминируют травянистые растения — 219 видов (87 %). Древесно-кустарниковая флора представлена бедно — 32 вида (13 %). Самоподдержание и раз-множение вида осуществляется семенами. Экологический оптимум D. fuchsia приходится на разнотравно-вейниковые, разнотравно-лабазниковые, злаково-луковые, хвощево-злаковые, осоково-кустарниковые фитоценозы.
Пустынный снегирь Bucanetes githagineus (M.H.C. Lichtenstein, 1823) в Казахстане
Authors: Федоренко В.А.
Published: April 2022

Пустынный снегирь Bucanetes githagineus (M.H.C. Lichtenstein, 1823) для современной территории Ка-захстана впервые отмечен в 1993 г. За последующие без малого три десятка лет эти данные пополнились незначительно — зафиксировано ещё восемь встреч, большая часть из которых относится к территории Мангышлака. Несмотря на то, что в Мангистауской области пустынный снегирь неоднократно отмечен в гнездовой период, до настоящего времени достоверных фактов его гнездования в Казахстане не было. В статье дан обзор всех находок пустынного снегиря для республики, кадастр для них, а также карта местонахождений пустынного снегиря, как в Казахстане, так и на территорияхсоседних стран. В ре-зультате полевых работ зарегистрировано новое местонахождение пустынного снегиря на юге респуб-лики — в Туркестанской области, в восточной части пустыни Кызылкум, в горах Каратау. Отмечено две пары птиц. Впервые на территории Казахстана найдено гнездо пустынного снегиря. Оно располагалось в нише одного из валунов, на каменистом склоне юго-восточной экспозиции горы Карамола. Гнездо находилось на стадии строительства лотка, проведены наблюдения за его строительством. При последующей проверке гнездо оказалось недостроенным и брошенным. Гнездо заколлектировано и помещено в коллекцию Института зоологии МОН РК. Таким образом, получены первые данные о биологии пустынного снегиря в Казахстане.
A comprehensive review on complex generics
Authors: Avhad Pratibha A. , Chalikwar Shailesh S. , Bhairav Bhushan A.
Published: April 2022

Complex generic is a generic with multifaceted dynamic constituent, multifaceted preparation, multifaceted path of administration, or multifaceted medicine device mixture. For over three decades, generics have been a desirable and cost-effective production route. Since the pharmaceutical cluster aimed at cheap generic medicines takes active development, biopharmaceutical firms remain focusingon multifaceted medicine, which provides extra worth towards affected person via speaking extra unmet requirements besides allow them to attain pharmaceutical souk variation and advanced using. The complexity of chemisimilar and biosimilar products has limited the replacement of unwieldy large-scale clinical trial data withsimpler, single-dose, pharmacokinetic and pharmacodynamic comparisons between test and reference. This limitation should be recognized by defining the sensitivity of any test used to detect differences in dose.
Атмосфералық жауын-шашын минерализациясының Қазақстан территориясы бойынша бақыланған өзгерісі
Authors: Құрманова М.С. , Мадибеков А.С.
Published: April 2022

Мақалада Қазақстан Республикасының территориясында атмосфералық жауын-шашын минерализациясын зерттеудің негізгі нəтижелері келтірілген. Бірқатар көлдераймағында жауын-шашын минерализациясының күрт төмендеуі мен жоғарылау тенденциясы бар екендігі анықталды. Жауын-шашын минерализациясының статистикалық маңызды өсу тренді Шалқар көлі (Ақтөбе облысы), Марқакөл көлі маңындарында бақыланса, төмендеу тренді Балқаш (батыс бөлігі), Билікөл, Үлкен Шабақты, Кіші Шабақты жəне Бурабай көлдері аумағында анықталды. Жауын-шашын жер үсті жəне жер асты суларының пайда болуының негізгі факторы болып табылады. Қазақстан территориясының аумағының үлкендігіне, орографиялық жəне климаттық жағдайына байланыстытерритория аумағында жауын-шашынның əркелкі таралуы бақыланады. Еліміздің едəуір бөлігі, таулы аймақтарды қоспағанда, атмосфералық жауын-шашынның тапшылығын сезінуде. Геохимия ғылымында атмосфералық жауын-шашын химиялық құрамын зерттеу атмосфера–жер беті–теңіз арасындағы тұздық алмасуды сипаттайды. Дүниежүзілік метеорологиялық ұйым (ДМҰ) бағдарламасы бойынша жауын–шашын сынамасынан: аниондар — сульфаттар, хлоридтер, нитраттар; катиондар — аммоний, натрий, калий, кальций, магний; ауыр металдар — қорғасын, мыс, кадмий, мышьяк, қышқылдық жəне үлесті электрөткізгіштік анықталады. Атмосфералық жауын-шашын химиялық құрамындағы əртүрлі қоспаларды білу агрохимиктер, гидрохимиктер, гидрогеологтар мен геохимиктер үшін табиғи жəне жер үсті суларын, топырақтың беткі қабатын зерттеу, алдын алу шараларын жүргізу үшін, сондай–ақ, санитарлық-гигиеналық мақсаттарға, өндірістік аудандардағы ауа ластану деңгейін анықтау үшінде өте маңызды.
Поиск зоонозных инфекций верблюдов, представляющих потенциальную опасность здоровью человека в Казахстане
Authors: Карамендин К.О. , Кыдырманов А.И. , Хан Е.Я. , Сейдалина Ə.Б. , Қасымбеков Е.Т.
Published: April 2022

Приводимые в мире исследования показывают важность контроля за распространением зоонозных ин-фекций. В последние годы выявлены новые, в том числе потенциальные пандемические штаммы коронавируса у верблюдов, что обусловливает необходимость регулярногомониторинга за состоянием ви-русных популяций у этого животного. Цель исследования заключается в выявлении спектра вирусных и бактериальных популяций, циркулирующих среди верблюдов в Казахстане и представляющих опасность для здоровья человека и животных. В статье использованы вирусологические и молекулярно-генетические методы: взятие биологических образцов от верблюдов, выделение из них нуклеиновых кислот, получение библиотек для секвенирования нового поколения, биоинформационный анализ полученных данных и серологические тесты. В результате массового параллельного секвенирования обнаружены контиги вирусов, классифицированные на 3 больших рода: Pestivirus, Circovirus и Hepevirus. Особый интерес вызывает обнаружение коротких последовательностей, сходных с таковыми вируса гепатита Е, что требует дальнейших, более глубоких исследований в этом направлении. Серологические исследования верблюдов Мангистауской области не выявили антитела на вирус Ближневосточного респираторного синдрома (БВРС, MERS-CoV), что говорит об отсутствии его циркуляции у верблюдов в Западном Казахстане либо о происшествии длительного времени после его возможного присутствия. Таким образом, исследование вирусных метагеномов верблюдов в регионе, близкому к Ближ-нему Востоку, является важной задачей научного поиска. Метагеномное исследование позволит выявить не только штаммы коронавируса, но и произвести анализ других неизвестных вирусных инфекций, важных как для сельского хозяйства, так и для здоровья человеческой популяции.
Simultaneous Immobilization of Gadolinium Ions and Di(o-carborano-1,2-dimethyl)borate on Fe3O4 Nanoparticles
Authors:   Institute of Nuclear Physic of the Republic of Kazakhstan, Korolkov I.V. , Zibert A.V. ,   L.N. Gumilyov Eurasian National University, Lisovskaya L.I. ,   Institute of Nuclear Physic of the Republic of Kazakhstan, Ludzik K. ,   University of Lodz, Anisovich M.V. ,   Republican Unitary Enterprise, Scientific-Practical Centre of Hygiene, Vasilyeva M.M. ,   Republican Unitary Enterprise, Scientific-Practical Centre of Hygiene, Shumskaya A.E. ,   Institute of Chemistry of New Materials, Usseinov A. ,   L.N. Gumilyov Eurasian National University, Yeszhanov A.B. ,   Institute of Nuclear Physic of the Republic of Kazakhstan, Zdorovets M.V. ,   Institute of Nuclear Physic of the Republic of Kazakhstan
Published: April 2022

Neutron capture therapy is a promising method for cancer treatment based on the targeted delivery of specific isotopes into cancer cells and subsequent irradiation with epithermal neutrons. As a result, a large amount of energy is released at a distance comparable to the size of the cell, destroying it from the inside. Magnetic iron oxide nanoparticles can be used for the targeted delivery of isotopes. In this article, iron oxide nanoparticles (Fe3O4) were modified with silanes and polyelectrolyte complexes for simultaneous immobilization of gado-linium ions and carborane compounds through ionic interaction for potential application in targeted delivery into cancer cells for neutron capture therapy. Structure, size and element composition was elucidated by the Fourier-transform infrared spectroscopy (FTIR), Energy-dispersive X-ray spectroscopy (EDA), dynamic light scattering (DLS) and X-ray diffraction (XRD) analysis. It was found that, according to EDA, resulting nano-particles consist of 15.4 % boron and 1.5 % gadolinium, with average hydrodynamical size of 386 nm meas-ured by DLS. An in vitro cytotoxicity test using HepG2 (a cancer cell line) and human skin fibroblasts (a normal cell line) showed minor cytotoxicity in concentration range from 0.05 to 1 mg/mL.
Editorial
Authors: Fiddian-Qasmiyeh Elena , Berg Mette Louise
Published: April 2022

Since the publication of our last issue, which included special sections on The Stakes of Sanctuary and Religion and Refugees, COVID-19 has continued to disrupt peoples’ lives and rhythms in multiple ways around the world. Vaccination programs have enabled many people in Europe and North America to start traveling again for work, to visit family, or for pleasure, yet long-standing global inequalities and inequities have persisted, with deadly effect. At the time of writing (end of February 2022), while 79 percent of the populations of high- and middle-income countries have received at least one vaccine dose, only 13 percent of people in low-income countries have been able to access the vaccine (Holder 2022), reflecting what Tedros Adhanom Ghebreyesu (Director-General of the World Health Organization) calls global “vaccine apartheid.”
Reflecting on Crisis
Authors: Manoussaki-Adamopoulou Ioanna , Sedacca Natalie , Benchekroun Rachel , Knight Andrew , Saavedra Andrea Cortés
Published: April 2022

This article offers a collective “gaze from within” the process of migration research, on the effects the pandemic has had on our interlocutors, our research fields, and our positionalities as researchers. Drawing from our experiences of researching a field in increasing crisis, and following the methodological reflections of the article written by our colleagues in this issue, we discuss a number of dilemmas and repositionings stemming from—and extending beyond—the effects of the COVID-19 pandemic. Focusing on issues of positionality, ethics of (dis)engaging from the research field, and the underlying extractivist nature of Global North academia, we propose our own vision of more egalitarian and engaged research ethics and qualitative methodologies in the post-pandemic world.
The Powerful (Vagueness of) Numbers?
Authors: Krause Ulrike
Published: April 2022

The Global Trends Reports represent UNHCR’s key tool to share information about annual developments in relation to displacement, primarily through numbers. Among the many subjects covered, they often also address different forms of accommodation. But how do such quantifications produce (non)knowledge and link with the humanitarian landscape? This article explores accommodation categories, quantifications, and local categorizations as presented in the Global Trends Reports published from about 2003 to 2020. While the numbers appear to display precise knowledge on refugees’ whereabouts, gaps prevail in the reports: accommodation categories remain undefined, calculations are partly unclear, and local recategorizations occur suddenly without explanation. This article argues that these issues produce nonknowledge, and that the reports’ continuous attention to accommodation data simulates refugees’ controllability and governability.
QSAR MODELING AND DESIGN OF A NEW MODEL OF ANTIHIV DRUG 1-ARYL-TETRAHYDROISOQUINOLINE DERIVED USING THE PM3 SEMIEMPIRICAL METHOD
Authors: T. Male Yusthinus , Sutapa I. W. , Kapelle I. B. , Lopulalan M.
Published: April 2022

Quantitative Structure-Activities Relationship Analysis (QSAR) on the 1-aryl-tetrahydroisoquinoline derivative as a candidate for the anti-HIV drug (Human Immunodeficiency Virus) has been done. The analysis using an electronic descriptor of atomic net charge, dipole moment, polarization, HOMO-LUMO energy, and log P was calculated using the PM3 semiempirical method. The best equation model is determined using multilinear regression analysis. The QSAR analysis show that the best QSAR equation model of 1-aryl-tetrahydroisoquinoline derivatives: pEC50= -23.019-10.867(qC3)-162.911(qC4)-107.057(qC6) + 53.621(qC8) - 0.047 (µ) + 0.158 (α) + 0.175 (log P); (n = 36; r = 0.935; r2 = 0.875; SE= 0.135927366; Fcount/Ftable= 7.945277618; PRESS = 2.857943). The compound with the higher activity value is the best theoretically derivative compound for the anti-HIV drug candidate. The new model of the 1-aryl-tetrahydroisoquinoline derivative from the design is expected to have better activity than the 1-aryltetrahydroisoquinoline derivative compound that already exists is 1-(6-acetylpyridine-2-yl)-7,8-methoxy-quinoline.
COLORIMETRIC METHOD FOR TOTAL PHENOLIC AND FLAVONOID CONTENT DETERMINATION OF FIG (Ficus carica L.) LEAVES EXTRACT FROM WEST JAVA, INDONESIA
Authors: Saptarini N.M. , Pratiwi R. , Maisyarah I.T.
Published: April 2022

Fig (Ficus carica L., Moraceae) contains phenolics, flavonoids, tannins, sesquiterpenes, and organic acids. These secondary metabolites content creates an opportunity to utilize fig as a functional food or standardized herbal preparations. This study aimed to determine the total phenolic and flavonoid content of fig leaves extract by the colorimetric method. In this study, fig leaves from Ciwidey District, West Java Province, Indonesia were used. Fig leaves were extracted with 70% ethanol by the maceration method. Folin-Ciocalteu method was used to determine total phenolic content and AlCl3 method was used to determine total flavonoid content. Fig leaves extract had total phenolic content of 2.52 ± 0.243 mg GAE/g simplicia and total flavonoid content of 2.028 ± 0.007 mg RE/g simplicia. Fig leaves from Ciwidey District, West Java, contain good total phenolic and flavonoid content, so they have the potential to be developed into standardized herbal preparations.
USING PREPARATIVE CHROMATOGRAPHY AND NMR/LCMS/FT-IR, ISOLATION, IDENTIFICATION, AND CHARACTERIZATION OF POSACONAZOLE OXIDATIVE DEGRADATION IMPURITIES
Authors: Prasad Ketha Naga Venkata Durga , Kolli Deepti
Published: April 2022

Posaconazole is a pharmacological ingredient that is used to treat fungal infections. It comes in the form of delayedrelease tablets. During the forced degradation studies of Tablets, two unknown oxidative degradation impurities were discovered. The impurities were made from Posaconazole using meta-Chloroperoxybenzoic acid as an oxidant in the degradation process. Preparative chromatography was used to separate impurities, and spectroscopic techniques such as IR, NMR, and MS were used to deduce the structures. For the measurement of the total of six associated impurities of Posaconazole in Delayed-Release Tablets, a reverse phase HPLC technique was developed and validated according to ICH Q2 criteria
MOLECULAR FIELD-BASED QSAR STUDIES AND DOCKING ANALYSIS OF MERCAPTOQUINAZOLINONE BENZENE SULFONAMIDE DERIVATIVES AGAINST hCA XII
Authors: P. Gopinath  , Kathiravan M. K.
Published: April 2022

Selective targeting of the tumor-associated hCA XII isozyme is a promising strategy to obtain effective and safer agents in cancer therapy. A series of mercapto-quinazolinone benzene sulfonamide derivatives were subjected to molecular field analysis to derive 3D-QSAR models. Structural properties such as physicochemical, topological, electro-topological, and quantum-chemical descriptors were calculated using the Molecular Design Suite of V-life MDS 4.6 Software. The contour map generated from the SA-kNN model explains the significance of electrostatic and steric descriptors for hCA XII binding interaction. Molecular docking studies favored structural insights in association with QSAR. Most interacting residues Asn67, Gln92, Thr199 and His119 stabilized the compounds in the active pocket. The results suggest structural insights as well as highlight the key binding features of mercaptoquinazolinone benzene sulfonamide derivatives against hCA XII which can be utilized for the design and development of potent leads.
GREEN SYNTHESIS OF REDUCED GRAPHENE OXIDE SILVER NANOCOMPOSITE USING Anisomeles malabarica (L.) R. BR. LEAF EXTRACT AND ITS ANTIBACTERIAL ACTIVITY
Authors: Rakkimuthu R. , Aarthi S. , Neelamathi E. , Sathishkumar P. , Anandakumar A. M. , Sowmiya D.
Published: April 2022

The development of new antimicrobial materials has arisen in response to the need to prevent and control the growth of pathogenic microorganisms without the use of antibiotics. The Silver (Ag) nanoparticles attached r-GO (rGO/Ag) nanocomposite was synthesised in the present work using a one-pot in-situ chemical reduction approach and studied for antibacterial property. We developed a rapid preparation of graphene from graphite using modified Hummers method and reduced by A. malabarica leaf extract. UV-Vis spectroscopy and FT-IR were used to characterize the synthesized GO and rGO–Ag nanocomposite. The antibacterial properties of the synthesized GO and rGo-Ag nanocomposite were evaluated against human pathogenic organisms like Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus using agar well diffusion method. At 50µl concentrations, synthesised GO inhibited Pseudomonas aeruginosa (19 mm) and rGO-Ag nanocomposite inhibited Staphylococcusaureus (28 mm).Antibacterial properties of the nanocomposites were found to be efficient against both gram positive and gram negative bacteria. Thus, green synthesized RGO-supported Silver nanoparticles play an important role in the medical disciplines.
STOPPED FLOW KINETICS AND MECHANISTIC STUDY OF PERIODATE DEGRADATION OF PERSIST CARCINOGENIC 2,6 XYLIDINE BY Mn(II) CATALYST
Authors: Saini Karuna , Kaushik R. D. , Singh Jaspal
Published: April 2022

The periodate oxidation of 2,6 xylidine catalyzed by Mn(II) in a solution containing acetone miscible in water was studied using stopped-flow kinetics. The reaction was progressed at 450 nm. The influence of various parameters such as pH, dielectric constant on the reaction was also investigated. Furthermore, various thermodynamic parameters and the value of rate constants were monitored. Tests for quinone, melting point, UV spectra, and FTIR spectrum were used to characterize the final product as 2,6 -dimethyl-p-benzoquinone. Besides, the reaction rate remains unaffected by free radical scavengers. The reaction stoichiometry was reported as 1 mol 2,6-XYL: 2 mol NaIO4. The rate law, that is, d[C]/dt = kK3K4Kw[Mn(II)] [2,6-XYL]0 [IO4 - ]0 [H+ ] / {K2Kw + (Kw+KbK2) [H+ ] + Kb (H+ ) 2} confirms the findings under pseudo-first-order conditions. The 1/kcat versus [H+ ] profile further anticipated the rate law.
Комп’ютерне моделювання молекулярних систем в підготовці вчителів хімії та інформатики
Authors: Моісеєнко Михайло Вікторович
Published: April 2022

Метою дослідження є проектування та реалізація комп’ютерно-орієнтованого навчання майбутніх учителів хімії та інформатики моделювання об’єктів (процесів, явищ та систем) квантової механіки на магістерському рівні вищої освіти. Задачами дослідження є обґрунтування необхідності навчання магістрів хімії – майбутніх учителів хімії та інформатики – комп’ютерного моделювання об’єктів квантової механіки за підтримки спеціалізованого програмного засобу «Активний конструктор ієрархічних систем», визначення змісту лабораторного практикуму з дисципліни (факультативного курсу) «Новітні інформаційні технології в наукових дослідженнях та освіті» та особливостей методики його навчання. Об’єктом дослідження є процес навчання бакалаврів та магістрів хімії – майбутніх учителів хімії та інформатики. Предметом дослідження є зміст та програмні засоби навчання комп’ютерного моделювання об’єктів квантової механіки. В роботі засвідчено необхідність ґрунтовного навчання майбутніх учителів хімії та інформатики теорії та практики комп’ютерного моделювання об’єктів квантової механіки, подано розгорнутий зміст комп’ютерно-орієнтованого лабораторного практикуму вибіркової дисципліни (факультативного курсу) «Новітні інформаційні технології в наукових дослідженнях та освіті» для магістрів спеціальності 014 Середня освіта (Хімія), зазначено особливості методики його упровадження. Результати дослідження планується узагальнити для формулювання рекомендацій щодо проектування освітніх стандартів та навчальних планів підготовки магістрів за спеціальністю 014 Середня освіта (Хімія) та спеціалізацією 014 Середня освіта (Інформатика).
Українськомовний міжособистісний конфлікт
Authors: Білоконенко Людмила Анатоліївна
Published: April 2022

У монографії проаналізовано міжособистісний мовний конфлікт як комунікативне явище. Узагальнено різні підходи до типології мовного конфлікту, виявлено його сутність і диференційні ознаки. Доповнено теоретичні положення щодо українськомовного конфлікту як соціокультурного, прагматичного та когнітивного явища, що формується в суспільстві відповідно до української національної самосвідомості. Типологізовано мовні маркери, які визначають українську репрезентаційну систему міжособистісного конфлікту. Уведено до наукового обігу поняття надтексту міжособистісного конфлікту, обґрунтовано критерії його вирізнення. Запропоновано наукову систематизацію моделей мовленнєвої поведінки осіб на різних стадіях конфлікту. Схарактеризовано особливості сприйняття міжособистісного мовного конфлікту в українському комунікативному середовищі. Монографія адресована науковцям, викладачам, аспірантам, студентам, а також усім, хто цікавиться актуальними проблемами сучасної української мови.
Дистрибутивні характеристики предикатів стану в українській літературній мові
Authors: Березовська-Савчук Наталя Анатоліївна
Published: April 2022

У монографії здійснено комплексний дистрибутивний аналіз прислівникових і дієслівних предикатів, що виражають семантичну категорію «стан» в українській літературній мові; обґрунтовано принципи організації синтагматики тих лексичних одиниць, які виступають організаційним центром речень із загальним пропозитивним значенням «стан»; подано визначення дистрибуції як основного способу виявлення синтагматичних властивостей мовних одиниць; розмежовано поняття сполучуваності, валентності, інтенції та дистрибуції; виявлено дистрибутивні характеристики безсуб’єктних предикатів стану в українській мові; описано дистрибутивне оточення суб’єктних предикатів стану; схарактеризовано обов’язкову й факультативну дистрибуцію суб’єктно-об’єктних предикатів стану. Для студентів філологічних факультетів, аспірантів, викладачів вищих навчальних закладів, усіх, хто цікавиться проблемами української літературної мови.
Романи "муженського циклу" Володимира Винниченка: проблематика, жанрово-стильові особливості
Authors: Варданян М. В.
Published: April 2022

У монографії досліджується проблематика та жанрово-стильові особливості романів В.Винниченка "Вічний імператив", "Нова Заповідь", "Лепрозорій", "Слово за тобою, Сталіне!". Розглядаються концептуально-жанрові пошуки митця у контексті його творчості та в контексті доби. Увагу зосереджено на осмисленні художньої моделі, в якій утілені соціально-філософські погляди концептуального письменника. З'ясовується специфіка творення конфліктів, композиції, структури образів персонажів як носіїв певних ідей, зверненість автора до символіко-міфологічної поетики, уточнюються жанрові номінації романів "муженського циклу", визначається їхній синтетичний характер.
Куницеві
Authors: Абелєнцев В. І.
Published: April 2022

У монографії, присвяченій питанням екології, поширення і господарського використання куницевих - цінних хутрових звірів фауни України, наведено загальну характеристику родини, діагнози родів та повні описи видів, вказано ворогів і паразитів куницевих та їх хвороби; даються рекомендації по регулюванню промислу і збільшенню чисельності корисних видів. Розрахована на спеціалістів - зоологів, біологів, що працюють у наукових, загальних учбових, сільськогосподарських та інших закладах, а також всіх, хто цікавиться сучасними відомостями про фауну України
Методика застосування рухливих ігор
Authors: Шутько В. В.
Published: April 2022

В методичних рекомендаціях представлені пропозиції практичного використання рухливих ігор в різних формах і проявах їх застосування у дітей шкільного віку. В кінці кожного розділу додаються питання для самоконтролю. Для студентів педагогічних вузів та вчителів фізичної культури.
Оцінка фізичної підготовленості студентів за курсами
Authors: Марчик В. І. , Макаренко Н. Г.
Published: April 2022

В роботі досліджували відмінності у фізичній підготовленості при порівнянні відповідних показників студентів (жіночої статті) першого і другого. Для оцінки фізичної підготовленості використана «сходова» проба Аронова, яка рекомендується для здорових людей у віці до 50 років Визначення оцінки фізичної підготовленості показало значне погіршення показників у студентів 2 курсу при порівнянні з показниками студентів 1 курсу. Відмічено, що планування одного заняття фізичного виховання на тиждень не сприяє розвитку морфологічних і функціональних можливостей студента, а тим більше формуванню навички до регулярних занять фізичними вправами.
Потреби студентської молоді у фізичному вдосконалені
Authors: Марчик В. І.
Published: April 2022

В роботі вивчали задоволення потреб студентів у фізичному вдосконалені через навчальний процес фізичного виховання у вузі. Серед студентів, що мають активну позицію до занять фізичними вправами пріоритети пропонованих видів спорту розподіляються за пріоритетом так: легка атлетика, спортивні ігри, плавання. Студенти з нейтральною позицією до занять не виявили явних пріоритетів з пропонованих видів спорту. Ідея існування спортивного клубу у вищому навчальному закладі з більшою різноманітністю видів фізичних вправ та їх вільним вибором не є популярною серед студентської молоді. Проведене дослідження дає підставу стверджувати, що переважна більшість студентів задовольняють свої потреби фізичного вдосконалення через існуючу систему організації фізичного виховання у вузі.
Функціональні можливості першокурсників спеціальної медичної групи
Authors: Марчик В. І. , Переверзєва С. В. , Андріанов В. Є.
Published: April 2022

В роботі досліджували відповідність функціональних показників студентів 1 курсу спеціальної медичної групи до середніх норм. В більшості показники ЧЧС є достатньо високими, що вказує на низький рівень функціонального розвитку. У студентів спецмедгрупи показники норми маси тіла за індексом Кветеля та життєвого індексу поступаються показникам студентів основної медичної групи.