bluuebunny/crossref_metadata_2025 huggingface dataset:
Appraisal of Urban Sprawl in Mega Cities of Punjab Pakistan in context of Socio-Political Issues using RS/GIS
Authors: Saifullah Muhammad , Zafar Memoona , Sohail Anam , Mehmood Faiza , Musharaf Muhammad , Khan Jehanzaib , Ashfaq Ayesha , Mahmood Syed Amer
Published: January 2023

Urbanization has become a hot issue in context of environmental and socio-political scenarios which is addressed at every forum internationally. The mega cities are considered the main origin of socio-economic development which caused to emerge a number of issues like biodiversity, environmental degradation, resource consumption, implementation of law and order and provision of basic facilities to the general public. The area under investigation consists of Lahore, Gujranwala and Sheikhupura. The study site was bounded by 73-75 E longitudes and 31-33 N latitudes. We used Landsat satellite data to map Spatio-temporal variations in urban sprawl from 1990 to 2019 with a temporal window of 15 years. The Landsat data is free, highly reliable and considered as primary source. The classification results show that the total area of study site was site was 29355 km2 including 21933km2 were green index 4595 km2 was under human settlements and 2827 km2 was the waterbody in 1990. The classification of Landsat image of the year 2005 describes that area of human settlements was increased to 9366 km2, the volume of water body was reduced to 2111km2 and the vegetation was also degraded to 17878km2. Again, the urban area was computed using satellite imagery for the year 2019 which was 16105km2 in 2019. Kappa stat proved the accuracy of supervised classification what was around 87%. Remotely sensed datasets proved the reliability of Landsat satellite images for estimation of urban sprawl during last three decades.
Flash flood simulation in the urbanised catchment: a case study of Bratislava-Karlova Ves
Authors:   Comenius University in Bratislava, RUSINKO Adam , HORÁČKOVÁ Šárka ,   Slovak Academy of Sciences
Published: January 2023

Flash floods are a dangerous phenomenon that generally affects small drainage basins. They are primarily initiated in the upper parts of the slopes, but their damaging effects are manifested mostly in residential areas, where naturally flowing streams were removed from the surface to the underground artificial channels. Therefore, there are no precise data about stream water levels available and only using surface runoff modelling is possible to simulate what happened during flash floods. Karlova Ves (Bratislava City District), formerly a small viniculture village, was threatened by floods (most probably including pluvial type) in history. In this paper, we used GRASS GIS tool r.sim.water to simulate the surface runoff of a flash flood that occurred in summer 2014 in the catchment of Čierny potok. The flood on 23 August 2014 was reported to have the highest rainfall per hour ~40 mm during the time of local meteorological measurements. The current orthophotomap was used to classify the land cover classes, which were assigned the value of the Manning’s roughness coefficient and infiltration rate. The topography was expressed by DTM from high-resolution LiDAR data. Our preliminary results indicate that land cover and land use are the essential factors that influence the initiation of flash floods, although the main driver of lower infiltration and change in flow direction is caused by urbanisation and a high proportion of impervious areas. Simulation showed that during 60 minutes of extreme rainfall (40 mm/hr) a surface runoff can reach a depth of water up to two meters in terrain depressions by a maximum discharge of 25 cubic meters. The revitalisation of natural urban areas by increasing vegetation cover in areas prone to flash floods and accumulation of water during higher rainfalls helps to prevent the damage caused by floods. URL: https://www.gcass.science.upjs.sk/
Immunotherapy in Small Cell Lung Cancer
Authors: Rossi Antonio
Published: January 2023

Small-cell lung cancer (SCLC) is extremely sensitive to standard treatments, including conventional cytotoxic chemotherapies and radiotherapy, and has poor prognosis and short survival. Standard therapies have reached a plateau of effectiveness and new therapeutic strategies are needed to improve SCLC patient outcomes going forward. Immunotherapy has revolutionised the treatment of solid malignancies, offering a novel way to harness the host immune system to target malignant cells in patients whose disease may no longer respond to cytotoxic therapy. This review describes the available data for the checkpoint inhibitors, such as anti-cytotoxic T-lymphocyte antigen-4 protein (CTLA-4), anti-programmed cell death-1 protein receptor (PD-1), and ligands (PD-L1 and PD-L2) alone or in combination with first-line chemotherapy or in relapsed SCLC. Several trials investigating immunotherapy in SCLC patients are ongoing and the results are awaited soon. Moreover, further immune checkpoint inhibitors directed against other targets, such as the killer-cell immunoglobulin-like receptor and lymphocyte-activation gene-3, are in clinical development.

Overall, the high expectations from the oncology community are that the drugs under development will offer new and improved treatment options for SCLC patients.
Torsion of Normal Adnexa in the Third Trimester of Pregnancy Mimicking Acute Appendicitis
Authors: Mathew Mariam , Al Ghaithi Huda , Al Shukaili Sumaiya , Shivrudraiah Girija
Published: January 2023

Maternal ovarian torsion in pregnancy is very rare. Non-specific symptoms, signs, and imaging findings make the diagnosis difficult. A delay in diagnosis can lead to irreversible damage to adnexa and fetal compromise. Difficulties encountered in the diagnosis and management of adnexal torsion in the third trimester of pregnancy are highlighted in this article.
Active Selection and Single Embryo Transfer: Insights from Virtual Trials
Authors: Scriven Paul N.
Published: January 2023

Transferring embryos that are most likely to successfully implant and develop is important in optimising the efficiency of assisted conception. Slow-freezing of spare embryos has a high attrition rate; thus, actively selecting a viable embryo for a fresh transfer can theoretically result in a superior cumulative live birth rate compared to a conventional assessment of morphology. However, with vitrification and its much lower attrition rate, active selection may not deliver an improved cumulative live birth rate, as more viable embryos may be excluded due to the limitations of the technique than are lost due to warming attrition. For some women, the principal benefits of active selection techniques are likely to be associated with a reduction in the number of miscarriages and a reduced time to achieve a successful pregnancy or start another stimulated cycle. Active selection procedures need to be safe, accurate, and effective, without jeopardising the chance of a live birth. The analysis presented in this paper shows that, from the perspective of a self-funding woman, adding a costly active selection option is entering into a lottery for a better result that is most likely to offer no advantage and even the possibility of an inferior outcome for some. Gauging willingness-to-pay to avoid miscarriage and to reduce treatment time is likely to be complex, and depends on who is making the decision and how they are counselled. Evaluating cost-effectiveness, for which the unit of health is one live birth, is unlikely to be helpful in supporting a case for public funding or private insurance for a better selection technique. The author of this paper explores the theoretical potential of active embryo selection to optimise a full cycle of assisted conception, with particular reference to single embryo transfer.
Reproductive Function and Fertility in Women with Congenital Adrenal Hyperplasia
Authors: Pereira Nigel , Lin-Su Karen
Published: January 2023

Congenital adrenal hyperplasia (CAH) refers to a group of disorders that are associated with defective adrenal steroidogenesis, the most common of which is 21-hydroxylase deficiency. The advent of neonatal screening, molecular genetics, and glucocorticoid and mineralocorticoid replacement has vastly improved the diagnosis and treatment of CAH; therefore, most infants and children with CAH successfully transition into adulthood. Several quality-of-life issues emanate from this transition, of which reproduction and fertility are notable. In this review, the authors appraise the effects of elevated androgens in CAH on the anatomic, hormonal, and psychosocial aspects of reproductive function. These CAH-associated alterations in reproductive anatomy or endocrine function can impair natural fertility, most often depending on the severity of CAH. In addition to assessing the fertility rates of women with CAH attempting natural conception, as well as those requiring assisted reproductive treatments, the authors also review data pertaining to the mode of delivery and pregnancy outcomes in these women. Finally, the importance of reproductive and preconception counselling in women with CAH attempting conception is briefly discussed.
Associations Between Emotion Regulation Strategies and Anxiety in Lithuanian Medical Students
Authors: Žukaitė Silvija , Antinienė Dalia
Published: January 2023

Background. Appropriate emotion regulation is crucial for medical students to properly prepare for the practical part of their career. Emotion dysregulation, however, is associated with maladaptive emotion regulation strategies, which in turn often causes higher levels of anxiety. This could lead to difficulties concerning the studying process and preparation for the future career. This research is conducted due to the lack of previous studies.

Methods. Medical students of Lithuanian University of Health Sciences participated in an online survey. There were a total of 98 female and 18 male students, mean participant age M = 21,6 (SD = 2,21). The survey consisted of 3 questionnaires – Cognitive Emotion Regulation Questionnaire – Short Form (CERQ-SF), GAD-7 and sociodemographic questions. Scales were used to assess emotion regulation strategies and subjective anxiety levels.

Results. Female students experience higher levels of anxiety compared to their male counterparts. High levels of anxiety are associated with year 2–6 students; 1st year students are the only ones experiencing low levels of anxiety. However, it is worth mentioning that no statistical significance groups was found in those groups. Results suggest a weak negative correlation between adaptive ER strategies and anxiety, with a moderate positive correlation between maladaptive ER strategies and anxiety. No statistical significance was found between genders, years of study or age concerning the use of ER strategies.

Conclusion. Our findings suggest weak negative correlation between adaptive ER strategies and anxiety; moderate positive correlation between maladaptive ER strategies and anxiety was also found.

Keywords: medical students, emotion regulation, anxiety.
Emotional states of people attending sports and health clubs during and after the period of the Covid-19 pandemic
Authors: Šniras Šarūnas , Klusaitis Medas
Published: January 2023

Background. The measures of social and physical isolation during the period of the Covid-19 pandemic had an influence on people’s way of life and mental health. It was noticed one of the biggest problems during the period of the Covid-19 pandemic was an increase of negative emotions and decrease of physical activity among people that usually do sports. In the article, the main attention is paid to emotional states of people attending sports and health clubs during and after the period of the Covid-19 pandemic.

Methods. The following research methods were applied: SAN questionnaire, interview survey and the situation anxiety assessment scale by Spielberger and Khanin. A Chi square (χ²) test was applied for the comparison of the results between the researched groups. The research was performed in the academic year 2021/2022 and 97 physically active people that did sports in sports and health clubs, including 35 women and 62 men, were researched.

Results. The results revealed the people attending sports and health clubs assessed their well-being during the period of the Covid-19 pandemic in the following way: even 46 percent of the researched assessed it as low, 37 percent indicated the average level and 17 percent – the high level. However, after the Covid-19 pandemic, just 24 percent of the researched assessed their well-being as low, 34 percent indicated the average level and 42 percent – the high level. The people that attended sports and health clubs assessed their activity during the pandemic: 48 percent indicated the low level, 31 percent – the average level, and 21 percent – the high level. These indexes became better after the pandemic: 28 percent assessed their activity as low and average, and 44 percent – as high. The pandemic restrictions also had a big influence on the mood of those researched: the level of the mood of the researched attending sports and health clubs was low with even 47 percent, average with 23 percent, and high with 30 percent. However, the mood indexes were distributed after the pandemic: 22 percent indicated the low level, 25 percent – the average level and 53 percent – the high level. It was noticed even 58 percent of the researched assessed their situation anxiety as high during the pandemic, 23 percent – as average, and 19 percent – as low. Meanwhile, after the pandemic, the same researched assessed their situation anxiety in the following way: 49 percent – as low, 25 percent – as average, and 26 percent – as high. Conclusions. The indexes of well-being, activity, mood and situation anxiety of people attending sports and health clubs were much better after the Covid-19 pandemic than during the period of the Covid-19 pandemic.

Keywords: Covid-19, sports and health clubs, emotional state, well-being, activity, mood, situation anxiety
Effects of Acute Noxious Heat Exposure on The Attention Required by Tasks of Three Levels of Difficulty in Young Healthy Men
Authors: Ivanovė Soneta , Brazaitis Marius
Published: January 2023

Background: This article discusses the current knowledge on the effects of heat stress on cognitive abilities. Whole-body hyperthermia (WBH) has a negative effect on mental performance. In this study, we investigated whether short-term whole-body immersion in water at 45°C (HWI-45°C), which induces a strong neurotransmitter and temperature flux without inducing whole-body hyperthermia, would impair mental performance in humans.

Methods: Fourteen men (aged 25±6 years) were enrolled in this study and participated in three experiments: (i) a brief (5-min) immersion of the whole body in 37°C water (WI-37°C); (ii) a brief (5-min) immersion of the whole body in 45°C water (HWI-45°C); and (iii) a control trial in a thermoneutral condition at an ambient temperature of 24°C and 60% relative humidity. Before and after immersion, cognitive performance was tested. All tests were performed in a quiet and semi-darkened laboratory.

Results: Baseline simple, 2-choice and procedural reaction time and percentage of correct answers did not differ significantly across all trials. 2-choice reaction time was reduced (i.e. faster reaction) only after immersion to 37°C water. Interestingly, only whole-body immersion to 45°C was a sufficient trigger to reduce procedural reaction time.

Conclusion: young healthy men do not deteriorate in response to whole-body hot water immersion for a short duration. By contrast, we here show faster reaction time in procedural reaction task, which was the most difficult of the three to perform.

Keywords: Heat stress, hot water immersion, cognitive performance.
Lyderystės raiška sporto organizacijose: Lietuvos sporto organizacijų vadovų ir darbuotojų požiūris
Authors: Drupė Skaistė
Published: January 2023

Straipsnyje analizuojama lyderystės raiška sporto organizacijose. Atlikus tyrimą nustatyta, kad idealus lyderis nagrinėto tipo organizacijose turi būti sutelkiantis, motyvuojantis, lankstus ir turėti stiprių sąsajų su sportu. Išryškėjo, kad lyderiams būdingas motyvavimas, lankstumas, o sutelktumas ir sąsajos su sportu pastebimos kiek rečiau. Lyderystės potencialą sporto organizacijose riboja kliūtys, kylančios iš išorinės aplinkos ir organizacijos lygmenyje. Išorinėje aplinkoje veikia biurokratija, įstatyminės bazės trūkumai ir spragos, pandemija, pokyčių neįgyvendinimas valstybiniame lygmenyje. Organizaciniame lygmenyje susiduriama su specialistų pritraukimo sunkumais, finansiniais apribojimais ir kt.
Raktažodžiai: lyderis, transformacinė lyderystė, pasidalytoji lyderystė, sportas, motyvacija
Vyresnių klasių mokinių probleminio interneto naudojimo ir su fiziniu aktyvumu bei psichologine sveikata susijusių rodiklių sąsajos
Authors: Jasulaitis Mindaugas , Miežienė Brigita , Emeljanovas Arūnas
Published: January 2023

Straipsnyje aprašyto bandomojo tyrimo metu buvo vertintos probleminio interneto naudojimo (PIN), fizinio aktyvumo (FA), sėsliai praleisto laiko (SPL) ir psichologinio distreso (PD) sąsajos tarp Lietuvos vyresnių klasių mokinių. Rezultatai parodė, kad fiziškai aktyvesni tiriamieji pasižymi mažesniu, o sėsliai daugiau laiko praleidžiantys – didesniu probleminiu interneto naudojimu. Nustatyta, kad fiziškai aktyvesniems tiriamiesiems būdingi mažesni PIN ir PD. Tik trečdalis vyresnių klasių mokinių yra pakankamai fiziškai aktyvūs. Merginos yra mažiau fiziškai aktyvios, daugiau laiko praleidžia sėsliai ir patiria daugiau psichologinio distreso nei vaikinai. Naudojimasis internetu tarp lyčių nesiskiria, o moksleivių amžius nesisieja su jų PIN, PD ir SPL.
Raktažodžiai: probleminis interneto naudojimas, vidutinis-didelis fizinis aktyvumas, psichologinis distresas
Neformaliojo sportinio ugdymo iššūkiai COVID-19 pandemijos metu
Authors: Nenartavičius Rokas , Fominienė Vilija
Published: January 2023

Straipsnyje analizuojama su kokiais iššūkiais sporto šakų trenerių nuomone susidūrė jie patys ir jų ugdytiniai COVID-19 pandemijos metu. Buvo išskirtas jaunųjų sportininkų motyvacijos sportuoti mažėjimas, jų negebėjimas išpildyti treniruočių sąlygų bei neigiama aplinkos, kurioje jie treniruojasi, įtaka sportinei veiklai. Treneriai, prisitaikydami prie pasikeitusių sąlygų buvo priversti papildomai ieškoti informacijos, investuoti savas lėšas į treniruočių procesą, suprasti treniruočių vedimo nuotoliniu būdu ypatumus, demonstruoti savo išradingumą vykdant užsiėmimus, nuolatos kelti sportininkų motyvaciją.
Raktažodžiai: pandemija, sportas, neformalus ugdymas, treneriai, sportininkai
Fabrication of Self-Healable, Robust, and Superhydrophobic Nanocomposite Films
Authors: Park Siwoo , Ha Young-Geun
Published: January 2023

Despite the recent advances in nature-inspired superhydrophobic surfaces with multifunctional properties such as self-healing, self-cleaning, antibacterial material, anti-biofouling, and oil-water separation in various industrial applications, there have been very few reports of robust superhydrophobic surfaces fabricated via a low-cost method. Herein, we report a rationally designed, self-healable, robust, and superhydrophobic nanocomposite film, fabricated by a one-step reaction process from a multi-component solution. These superhydrophobic nanocomposite films can be readily fabricated over a large area with high throughput via simple spray coating of the component solution. As the spray-coating materials, we used functionalized hydrophobic silica nanoparticles (hydrophobic-SiO2 NPs) to achieve hierarchical textured structures, and low surface energy. Then, thermal crosslinkers and long hydrocarbon silanes were added to improve the stability and hydrophobicity of the fabricated nanocomposite films. Because of the synergetic effect of the hydrophobic NPs and crosslinked polymeric compounds, the spray-coated superhydrophobic nanocomposite films exhibited excellent superhydrophobicity (static water contact angles > 150°), high transparency (>80%), high stability, and self-healing abilities. Tests confirmed the rationally designed, solution-based spray coating method provides a simple route to construct transparent, robust, and self-healing superhydrophobic surfaces, with high throughput and large area, which can be utilized in various industrial applications, including conventional products and advanced non-wetting surfaces.
PKM Pengembangan Wisata Edukasi Pedesaan Berbasis Budaya Berkelanjutan di Desa Kedung Caluk Krejengan Probolinggo
Authors: Febrianto Achmad , Robiyono Robiyono , Zainullah Zainullah , Wafi Abdul , Firmansyah Fauzan
Published: January 2023

Objek wisata Kingkong Park merupakan objek wisata baru di Desa Kedungcaluk, Kecamatan Kerejengan yang memiliki banyak destinasi wisata. Wisata Kingkong Park memiliki sumber daya alam yang melimpah, sehingga memiliki potensi wisata yang cukup besar untuk dikembangkan sebagai daya tarik wisata selanjutnya. Program yang dilaksanakan adalah untuk lebih mengembangkan wisata Kingkong Park. Melihat dari potensi sumber daya alam yang ada di Desa Kedungcaluk Kecamatan Kerejengan Kabupaten Probolinggo dalam pengelolaan pariwisata terdapat beberapa aspek yaitu perencanaan, pengelolaan, monitoring dan evaluasi, namun dalam pelaksanaannya belum optimal untuk itu diperlukan pengelolaan pariwisata. Pengembangan sumber daya manusia, masyarakat lokal yang ramah dan pembentukan komunitas lingkungan yang berdaya Cara untuk meningkatkan perekonomian masyarakat adalah dengan mengadakan event-event yang melibatkan masyarakat sekitar objek wisata, menjaga program bank sampah, dan menjalin kerjasama dengan pihak ketiga. Dampak positifnya adalah terbukanya lapangan pekerjaan, peningkatan pendapatan masyarakat, pemanfaatan fasilitas wisata. Dampak negatifnya adalah pengembalian investasi yang tidak pasti
Assessment of Groundwater and Surface-Water Resources of Gushkara in Purba Bardhaman (West Bengal, India) using the Water Quality Index
Authors: Nandi Roy Aparnita , Manas Paramanik
Published: January 2023

Survival of life on earth indispensably depends on water. Population explosion and its consequences resulted in the usable water sources being unusable in many regions. Regular monitoring of water quality becomes necessary to protect public health. The present study aimed to evaluate the water quality status of various water resources of Gushkara (West Bengal, India). The result showed that the status of the water quality index (WQI) of the studied surface-water sources is ‘poor’ or ‘very poor’ (ranges 50.582 - 87.969) whereas the groundwater and municipal water supply are rather safer (ranges 15.804 - 36.210). There is also an indication of faecal coliform contamination in surface-water sites. Overall water quality is better in winter than other two seasons. Some parameters in surface-water crossed the recommended level while some reached near that level. So immediate attention is necessary to rectify the situation.
Green Manufactured Nanoparticles as Potent Larvicides: A Short Review
Authors: Priyadarshini J. Flora , Ashok K.  , Babu M.
Published: January 2023

Resistance and insufficient attention to the applicable standards are typical explanations of pesticide treatment failure to insecticide resistance such as organophosphates and control agents. There is therefore a need for a safer, cheaper and more efficient investigation of mosquito control agents with new modes of actions. Recently, biologically produced nanoparticles have been seen as a possible strategy to fighting malaria vectors and also as a therapy for mosquito illnesses. Here we provide current understanding on the efficacy of biogenic nanoparticles (NPs) in vector-borne conditions.
In Vitro Antioxidant and Antimicrobial Activity of Isolated Flavonoid from the Methanolic Extract of Spermacoce hispida Leaves
Authors: Durgadevi S.  , Rose A. Leema , Vidhya S.  , Priya F. Janeeta , Kanmani P. Lydia Festus
Published: January 2023

The purpose of this research was to separate the flavonoid component of the Spermacoce hispida plant that is responsible for its medicinal effects. A methanolic extract of Spermacoce hispida leaves was used to study the separation of flavonoids from a plant component. Phytochemical analysis of methanol extract confirmed the presence of flavonoid compounds. The extracted flavonoid component was refined using thin-layer chromatography and column chromatography. The structures of the isolated compounds were characterised using UV-Visible, FT-IR, 13C, 1H NMR, and Mass spectroscopy. Therefore, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[-Lrhamnopyranosyl-(16)—D-glucopyranosyloxy] was given as the name for the isolated molecule. There has to be further biological investigation of this plant's isolated flavonoid. Flavonoids are a distinct class of plant secondary metabolites having pharmacological benefits that have been used for centuries in traditional medicine. They support a diverse array of medical procedures that may provide novel and therapeutic medication discoveries. Flavonoids' potential as antioxidants in the face of oxidative stress has been the subject of a lot of recent research. To what extent flavonoids may serve as antioxidants and as antimicrobials is explored in this study.
Evaluation of Biochemical and Hematological Parameters in Polycystic Ovarian Syndrome Among Urban College Girls
Authors: Sujatha M.  , Safiya  , Reeba  , Annambhotla Pavani
Published: January 2023

Polycystic Ovarian Syndrome (PCOS) is characterised by increased level of androgens (Male hormones) and decreased level of female hormones causing a set of symptoms in affected females of reproductive age. The present study was aimed to find out the prevalence of PCOS among the urban College girls at Chennai and to analyse the effect of PCOS on hormones, biochemical as well as haematological parameters in the subjects. Out of 1500 urban college girls those who have participated in the survey at Chennai, 147 girls aged between 19-22 were found to have PCOS during the experimental period which was held from July 2019 to March 2020. The percentage of PCOS prevalence among the urban college girls was claimed to be 9.8 % (approximately 10 %). The percentage of obesity, overweight, normal weight and underweight among the urban college girls was arrived by calculating their Body Mass Index (BMI). Out of 1500 urban girl participants, 243 (16.2%) were found to have BMI in between 25 – 29.9 (overweight). It has been observed that 78 girls (5.2%) had BMI more than 29.9 (Obesity). Nearly 117 girls (5.8%) showed BMI lesser than 18.5 (Underweight). Out of 78 obese girls about 40 girls were found to have PCOS (51.28%) and nearly 85 girls had PCOS out of 243 overweight girls (34.97%). The levels of testosterone were found to be increased and progesterone was found to be decreased in test group. High sensitive C reactive protein (HS - CRP) levels showed significant (p
Biogenesis of Metal Nanoparticles and its Potential Targeted Drug Delivery Systems for Urolithiasis
Authors: Priya F. Janeeta , Rose A. Leema , Vidhya S.  , Arputharaj A.  , Manimegalai V.  , Durgadevi S.
Published: January 2023

Urinary stones are a biggest issue that people experience worldwide. Urinary tract infections that lead to struvite urinary stones are the result of improper organ function, particularly kidney. The present study concentrated on an economical and environmentally friendly method for producing copper nanoparticles utilizing Eclipta prostrata leaves extract as a reducing and capping agent. UV-Visible spectroscopy shows SPR band at 256 nm which was used to validate the synthesis of copper nanoparticles. According to FT-IR Spectroscopic investigations, phytoconstituents have a major role in the reduction and capping of copper nanoparticles. E. prostrata mediated copper nanoparticles were crystallized and had a spherical shape, according to XRD and SEM. The EDX analysis showed the elemental composition and the amount of copper nanoparticles. The copper nanoparticles mediated by E. prostrata were found to have an inhibitory efficiency of 88.3% showing that they were an effective inhibitor for the struvite crystals. According to FT-IR spectra the shifting of the band confirmed that the phytocomponents present in E. prostrata leaves extract is responsible for anti-urolithiatic activity.
Forest Cover Change Detection using Geospatial Technologies in Chandaka National Park, Odisha, India
Authors: Joshi K.  , K.M. Sethy
Published: January 2023

Forest plays a vital role in carbon sequestration and climate regulation. A crucial tool for managing forest, particularly in protected regions, is keeping track of how the land cover changes in natural places. Using geospatial approaches, such as remote sensing and geographic information system (GIS), the present study has revealed spatio-temporal changes in land use categories and forest cover in the Chandaka National Park of Odisha, India, throughout the period of 1980-2020. The Landsat, LISS III and Sentinel satellite images of the year 1980, 2000 and 2020 were utilized respectively to map five land use land cover categories i.e. deciduous broadleaf forest, crop land, mixed forest, scrub land and water bodies in this preserved area. The satellite images were classified using a Supervised Classification method using Maximum Likelihood algorithm and ground control points (GCPs) were used for the spatial statistical analyses. The overall accuracies of the classification method in land cover categories in year 1980, 2000 and 2020 were 90.45%, 92.76% and 94.68%, respectively. Elsewhere, in order to study land use land cover (LULC) change and loss in forest of the Chandaka National Park, LULC classification, per-pixel scales post classification and self-knowledge on the LULC change process were used. The LULC change detection results showed that deciduous broadleaf forest decreased from 179.01 sq. km (76.66%) in 1980 to 132.75 sq. km (56.85%) in 2020, while mixed forest cover increased by 8.17 sq. km (3.50%) in 1980 to 38.84 sq. km (16.63%) in 2020. Crop land, Scrub land and Water bodies were also increased by 3.34%, 3.27% and 0.07%, respectively. Two significant change processes in the area are the logging activities in several places for timber and the conversion of natural forests with plantation. Agriculture expansion in the forest’s periphery is linked to the dramatic decline in forest cover change. The decline in forest cover is also a result of the production of charcoal and lumber exploitation. Overall, our findings indicated that more public awareness and participatory forest management are necessary to preserve Chandaka National Park. This study highlights the use of geospatial technologies in understanding the changes in LULC in the Chandaka National Park.
Effect of a Suspension of Carica papaya Leaf Extract on the Thrombocytopenia Induced by Carboplatin in Mice
Authors: I.S. Chakrapani , Srinivas N.  , Kumar P. Anil , Jayappa K.  , Rajasekhar M.
Published: January 2023

A low platelet count characterises thrombocytopenia. Thrombocytopenic disorders (dengue, chikungunya, malaria, etc.) are on the rise in cities. This is now present in over 125 countries. Low platelet counts are caused primarily by decreased platelet generation and increased platelet degradation. It has been shown in several research that papaya leaf extract may increase platelet count. The major objective of the proposed research was to examine the haematology and histopathology of different organs for any adverse effects of Carica papaya leaf extract on raising platelet count in induced thrombocytopenic experimental animals. To test whether a rise in platelet count was present, papaya leaves were macerated in a mixture of nhexane, acetone, ethanol, and methanol in distilled water for 8 h using a Soxhlet device. Toxicologists may benefit from experimental animal haematological and histopathological studies.
Impact of Simplified Kundalini Yoga Practices on Thyroid Stimulating Hormone and Anxiety in Middle-Aged Menopausal Women
Authors: Valli T.  , Arunachalam P.
Published: January 2023

In this study, one hundred and twenty middle-aged menopausal women aged forty to fifty were chosen at random from Chennai, India. Forty women were screened before being divided into two groups of twenty each. The same dependent variable, thyroid stimulating hormone, and anxiety, were reviewed after twelve weeks in both groups. To establish the significant difference between the dependent variable, thyroid-stimulating hormone, and anxiety, an analysis of variance was used. The level of statistical significance was fixed at 0.05.
Foot Muscle Strength, Muscle Shortness, Balance, and Shoe Preferences in Different Foot Postures
Authors: ÜNVER Banu , TAŞKIRAN Hanifegül , AKGÖL Ahmet Cüneyt
Published: January 2023

Objective: The aim of this study was to investigate the foot muscle strength, muscle shortness, tibialis posterior endurance, balance, and the shoe preference differences between the neutral and pronated foot posture.

Methods: Forty-nine participants consisting of 23 women and 26 men, and age of between 18 and 45 years were participated in the study. Foot posture, medial longitudinal arch height, height, gastrocnemius and hamstring muscle shortness, foot and ankle muscle strength, tibialis

posterior muscle endurance, static balance, and shoe preferences of the participants were evaluated. Subjects were recruited into two groups according to their foot posture evaluated with Foot Posture Index: as those with neutral and pronated foot posture.

Results: Navicular drop, gastrocnemius, and hamstring muscle shortness were significantly higher in participants with pronated foot posture compared to those with neutral foot (p0.05).

Conclusion: Flexibility of gastrocnemius and hamstring muscles were reduced, but foot muscle strength, tibialis posterior muscle endurance, and balance remained unaffected in young individuals with excessive foot pronation. Moreover, shoe preferences may not affect the foot posture in young people. Although all age-related biomechanical effects of foot pronation are not well known yet, muscle shortness seems to arise earlier than muscle weakness and reduced balance in pronated foot posture
Evaluation of Nursing Care in the Early Postpartum Period
Authors: KARAÇAY YIKAR Seda , GÖZÜYEŞİL Ebru , NAZİK Evşen , VAR Ebru
Published: January 2023

Objective: Evaluation of the care given in the postpartum period is vital in terms of the quality of care. The aim of this study was to evaluate nursing care in the early postpartum period.

Methods: This descriptive and cross-sectional study was conducted in a postpartum clinic between December 2016 and January 2017 with 130 mothers in postpartum period, and 18 nurses and midwives working in the same postpartum clinic. Data were collected using a personal information form, and the Postpartum Nursing Care Evaluation Tool (PPNCET). The data analysis was conducted using percentages, arithmetic mean, independent samples t-test, Mann-Whitney U test, and Kruskal-Wallis test.

Results: The mean age of the mothers was 26.80 ± 4.90, and of the nurses and midwives was 35.83 ± 12.14. The mean PPNCET score of the mothers was 141.58 ± 32.03. The mean care subscale score of the mothers was 69.88 ± 12.06 and of the education subscale was 71.70 ± 19.97.

The mean PPNCET score of the nurses and midwives was 153.50 ± 23.18. The mean care subscale score of the nurses and midwives was 73.38 ± 8.84, and the mean education subscale score was 80.11 ± 14.33.

Conclusions: The mean PPNCET score of mothers and nurses and midwives were higher than the average. Higher PPNCET scores of the nurses and midwives compared to the mothers suggests that either the postpartum care given was not perceived as adequate by the mothers, or the care was not served in adequate quality. To increase postpartum care satisfaction of the mothers, involving nurses and midwives in the care process more is suggested. In line with these results, planning in-service training programs to develop the knowledge and skills of the nurses and midwives would be beneficial in increasing the quality of service
A prospective study concerning the effect of pharmaceutical care services on patients with heart failure
Authors: TANER Neda , BERK Barkın
Published: January 2023

Objective: Heart failure (HF), caused by an abnormality in cardiac function, is the inability of heart tissue to pump blood or deliver sufficient oxygen, resulting in abnormal diastolic volume. Drug-Related Problems (DRPs) can cause significant but preventable morbidity and mortality once specific medication errors and their contributing factors are identified. The aim of this prospective study is to determine the effect of pharmaceutical care in patients with heart failure in a Turkish hospital.

Methods: A total of 160 patients with heart failure (80 patients in the control group, 80 patients in the intervention group) were examined at a university hospital. The results of the Pharmaceutical Care Survey were evaluated in accordance with the objective of the study. In addition, using the Pharmaceutical Care Network Europe (PCNE) classification system V8.01, the role and importance of the clinical pharmacist in identifying, preventing and resolving drug-related problems encountered during the treatment of two groups was assessed. The number and causes of potential DRPs were taken into scrutiny.

Results: Comparing the results of the Pharmaceutical Care Survey in both groups at the end of the 6th month, the study group shows a

significant improvement in the rates of “forgetting to take medication” (2.9%) and “experiencing any side effects from your drug” (4.5%). Compared to other problems, ineffectiveness of the drugs used in treatment was reported as the most common drug-related problem (n=23; 28.7%) in the study group (p
The Effect of Duration of Active Labor Phase on Postpartum Fatigue and Comfort
Authors: GÖKER Nuray , BİLGİN Zümrüt
Published: January 2023

Objective: This study aims to examine the effect of the duration of the active labor phase on postpartum fatigue and comfort. Methods: This descriptive study was conducted in a maternity hospital in Istanbul, Turkey date 2018. Nulliparous pregnant women without any risk (n: 120) participated in the study. Data were collected using the “Information Form”, the “Visual Analogue Scale”, the “Postpartum Comfort Scale” and the “Visual Analogue Scale for Fatigue”, and statistically analyzed. Results: The mean age of the women was 23.66±4.24 years. 22.5% felt very tired in the postpartum period. Their mean duration of active labor phase was 5.00±1.88 hours. Their Postpartum Comfort Scale and Visual Analogue Scale for Fatigue mean scores were 131.30±13.39 and 96.67±47.82, respectively. Conclusion: Duration of active labor phase did not affect postpartum fatigue and comfort of women
Phylogenomic resolution of order- and family-level monocot relationships using 602 single-copy nuclear genes and 1375 BUSCO genes
Authors: Timilsena Prakash Raj , Wafula Eric K. , Barrett Craig F. , Ayyampalayam Saravanaraj , McNeal Joel R. , Rentsch Jeremy D. , McKain Michael R. , Heyduk Karolina , Harkess Alex , Villegente Matthieu , Conran John G. , Illing Nicola , Fogliani Bruno , Ané Cécile , Pires J. Chris , Davis Jerrold I. , Zomlefer Wendy B. , Stevenson Dennis W. , Graham Sean W. , Givnish Thomas J. , Leebens-Mack James , dePamphilis Claude W.
Published: January 2023

We assess relationships among 192 species in all 12 monocot orders and 72 of 77 families, using 602 conserved single-copy (CSC) genes and 1375 benchmarking single-copy ortholog (BUSCO) genes extracted from genomic and transcriptomic datasets. Phylogenomic inferences based on these data, using both coalescent-based and supermatrix analyses, are largely congruent with the most comprehensive plastome-based analysis, and nuclear-gene phylogenomic analyses with less comprehensive taxon sampling. The strongest discordance between the plastome and nuclear gene analyses is the monophyly of a clade comprising Asparagales and Liliales in our nuclear gene analyses, versus the placement of Asparagales and Liliales as successive sister clades to the commelinids in the plastome tree. Within orders, around six of 72 families shifted positions relative to the recent plastome analysis, but four of these involve poorly supported inferred relationships in the plastome-based tree. In Poales, the nuclear data place a clade comprising Ecdeiocoleaceae+Joinvilleaceae as sister to the grasses (Poaceae); Typhaceae, (rather than Bromeliaceae) are resolved as sister to all other Poales. In Commelinales, nuclear data place Philydraceae sister to all other families rather than to a clade comprising Haemodoraceae+Pontederiaceae as seen in the plastome tree. In Liliales, nuclear data place Liliaceae sister to Smilacaceae, and Melanthiaceae are placed sister to all other Liliales except Campynemataceae. Finally, in Alismatales, nuclear data strongly place Tofieldiaceae, rather than Araceae, as sister to all the other families, providing an alternative resolution of what has been the most problematic node to resolve using plastid data, outside of those involving achlorophyllous mycoheterotrophs. As seen in numerous prior studies, the placement of orders Acorales and Alismatales as successive sister lineages to all other extant monocots. Only 21.2% of BUSCO genes were demonstrably single-copy, yet phylogenomic inferences based on BUSCO and CSC genes did not differ, and overall functional annotations of the two sets were very similar. Our analyses also reveal significant gene tree-species tree discordance despite high support values, as expected given incomplete lineage sorting (ILS) related to rapid diversification. Our study advances understanding of monocot relationships and the robustness of phylogenetic inferences based on large numbers of nuclear single-copy genes that can be obtained from transcriptomes and genomes.
Cumulative Antibiogram: A Rapid Method to Hinder Transmission of Resistant Bacteria to Oral Cavity of Newborn Babies
Authors: Malița Mădălina Adriana , Manolescu Loredana Sabina Cornelia , Pîrvu Cristina Florentina , Costea Radu Catalin , Marcov Elena Cristina , Burlibasa Mihai , Pîrvu Daniela Aurelia , Burlibașa Liliana , Radu Mihaela Corina , Prasacu Irina , Perieanu Viorel Ștefan
Published: January 2023

Background: A rapid bacterial diagnostic is needed more and more in the treatment of patients, because of the emergence of antibiotic resistance. The cumulative antibiogram, an annual report that monitors antimicrobial resistance trends in health care facilities, may provide a profile of empirical therapy useful in diverse emergency situations, such as transmission of resistant bacteria to oral cavity of newborn babies. We aimed to draw a profile of antibiotic resistance encountered. Methods: We assessed the antibiotic resistance (ABR) profile in childbearing women and newborn babies in Ploiesti Obstetrics and Gynecology Hospital by the disk diffusion method characterizing the multidrug-resistant organisms after isolation and identification by phenotypic tests. Extended-spectrum β-lactamase (ESBL)-producing Enterobacterales (ESBL-E), Carbapenem-resistant Enterobacterales (CRE), vancomycin-resistant Enterococci (VRE), methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant Group B Streptococcus (VR-GBS) were detected. Results: The prevalence of antibiotic resistance was 11.32% (53/468), while the prevalence of the ESBL-E, MRSA, VRE and VR-GBS strains was 8.34% (39/468). Within the bacteria isolated from fifty-three childbearing women, the prevalence of ESBL-E, MRSA, VRE and VR-GBS was 22.64% (12/53), 32.08% (17/53), 11.32% (6/53) and 7.55% (4/53). In the whole studied group, the prevalence was 2.56% (12/468), 3.63% (17/468), 1.28% (6/468) and 0.86% (4/468). Resistant bacteria were detected at birth in the oral cavity of the newborn babies in all cases. Maternal and neonatal isolates shared similar characteristics. Conclusions: Cumulative antibiogram is useful in case of empiric treatment needed in diverse emergencies, such as transmission of resistant bacteria to oral cavity of newborn babies.
Nutritional and Functional Properties of Novel Italian Spray-Dried Cricket Powder
Authors: Ruggeri Marco , Bianchi Eleonora , Vigani Barbara , Sánchez-Espejo Rita , Spano Mattia , Totaro Fila Carlotta , Mannina Luisa , Viseras César , Rossi Silvia , Sandri Giuseppina
Published: January 2023

Insects, especially crickets, have been proposed as a novel source of nutrients in human nutrition since they possess bioactive molecules, including high protein content, lipids, chitin, vitamins and minerals. In this work, the nutritional and functional properties of a novel Italian spray-dried (SD) cricket powder were evaluated. The powder was characterized by physico–chemical properties (morphology, size distribution, solid state, thermal profiles, and surface zeta potential), and antioxidant properties. Moreover, preclinical properties (cytocompatibility and pro-inflammatory immune response) were assessed. The powder was characterized by microparticle structure with bulges and rough surfaces, showing distinctive antioxidant properties. The preclinical results suggested that the SD crickets were biocompatible towards Caco-2 and macrophages without immune response, representing an interesting material for the food industry that could provide health benefits in addition to the basic nutritional value of traditional foods.
Bio-Functional Activities of Tuscan Bee Pollen
Authors: Chelucci Elisa , Chiellini Carolina , Cavallero Andrea , Gabriele Morena
Published: January 2023

Bee pollen represents one of the most complete natural foods playing an important role in the diet for its health qualities and therapeutic properties. This work aimed to characterize a Tuscan bee pollen by evaluating its phytochemical profile and the in vitro and ex vivo antioxidant activities. The isolation and taxonomic and functional characterization of yeasts in the sample has been also conducted. Finally, the pollen anti-inflammatory potential has been assessed on a TNFα-inflamed human colorectal adenocarcinoma cell line (HT-29). Our results highlighted a good phytochemical composition in terms of polyphenols, flavonoids, flavonols, monomeric anthocyanins, and carotenoids. In addition, we detected good antioxidant activity and radical scavenging capacity by in vitro and ex vivo assays, as well as good antioxidant activity by isolated yeasts. Data showed no cytotoxic effects of bee pollen extracts, with average viability values >80% at each tested dose. Moreover, TNFα treatment did not affect HT-29 viability while upregulating IL-8, COX-2, and ICAM-1 gene expression, otherwise reduced by both doses of bee pollen. In conclusion, our sample represents an interesting functional food and a potential probiotic product, having high phytochemical compound levels and good antioxidant activities, as well as anti-inflammatory effects on the TNFα-inflamed HT-29 cell line.
Investigation of Beat Wave Propagation along Lossy Dielectric Bar for Wind Tunnel Microwave Experiments
Authors: Bao Rong , Peng Xin , Yang Yin , Xiong Neng , Tao Yang , Wu Jifei , Liu Dawei
Published: January 2023

Lossy dielectric bars have potential applications in high power microwave (HPM) radiation-effect experiments performed in wind tunnels. Under plane excitation, beat wave patterns are observed along lossy and lossless dielectric bars in 3-D electromagnetic simulation results. Mode analysis is performed to clarify the two main modes in the beat waves—the leaky and guided modes. Comparisons are made between the theoretical and simulated results and acceptable agreements are obtained. The absorbing array of lossy dielectric bars is further investigated. The array can attenuate 90% of the microwave power at 10 GHz when a ten-meter series of such arrays is arranged. It is expected that the proposed absorbing array can achieve the required attenuation, considering that the testing object under microwave radiation is also an absorbing structure itself.