bluuebunny/crossref_metadata_2025 huggingface dataset:
The influence of metformin and empagliflozin administration on gut microbiota in individuals with type 2 diabetes mellitus and hypothyroidism
Authors: Moskva K.A. , Kikhtyak O.P. , Kikhtiak T.A. , Farmaha M.L. , Farmaha M.L. , Leshchuk Y.S.
Published: August 2024

Background. There is a lack of studies focusing on the combined impact of metformin, empagliflozin, and levothyroxine on the gut microbiota in patients with type 2 diabetes mellitus (T2DM) and hypothyroidism. The purpose of the study was to examine how the combination of metformin and empagliflozin affects gut microbiota composition in patients with type 2 diabetes and hypothyroidism. Materials and methods. We enrolled 47 patients who have been receiving hormone replacement therapy with levothyroxine at a stable dose over the past 2 years and were newly diagnosed with T2DM. All participants were divided into two groups and received either metformin alone or metformin plus empagliflozin for 6 months. Metabolic and hormonal parameters were measured before and after treatment, and stool samples were analyzed using PCR sequencing. Results. The study found that in both groups, there was an improvement in carbohydrate metabolism, lipid profile, and liver transaminases after treatment. The group treated with metformin plus empagliflozin had a more significant reduction in glucose, glycated hemoglobin, and atherogenicity coefficient than the group treated with metformin alone. We also found that combination therapy resulted in lower levels of Firmicutes and an increase in the number of Actinobacteria, as well as a higher ratio of Bacteroides fragilis to Faecalibacterium prausnitzii. Conclusions. The study shows for the first time that the combination of metformin, empagliflozin, and levothyroxine can directly affect the gut microbiota composition in patients with T2DM and hypothyroidism. These changes may be necessary for treating this cohort of patients and require further investigation.
Зв’язок функції щитоподібної залози матері з плацентарною гемодинамікою під час вагітності
Authors: Paienok O.S. , Protsiuk R.G. , Paienok A.V. , Zadorozhna B.V. , Hrytsyshyn B.R. , Ihnatovych S.V.
Published: August 2024

Проведено обстеження 164 вагітних жінок, які були розділені на три групи. До І групи увійшли 76 вагітних (46,4 %) з еутиреоїдним зобом I–IІ ступеня. Другу групу становили 63 жінки (38,4 %) із субклінічним гіпотиреозом та дифузним зобом I–IІ ступеня. Третя група була контрольною та складалася з 25 (15,2 %) вагітних без патології щитоподібної залози. Вивчали стан плаценти із характеристикою ультразвукової плацентографії, визначали порушення дозрівання плаценти, площу, локалізацію, виявляли патологічні зміни плацентарної тканини. Оцінювали зміни систолічно-діастолічного співвідношення в маткових артеріях, артеріях пуповини, визначали індекс резистентності в маткових артеріях та пульсаційний індекс в аорті та середній мозковій артерії плода за допомогою методу кольорового доплерівського картування кровотоку в системі «мати — плацента — плід». При вивченні ехографічної картини структурних змін плаценти виявлено вірогідне порушення її дозрівання, особливо в групі з еутиреоїдним зобом. Ультразвуковий скринінг встановив, що в кожної другої вагітної з тиреопатією стан плаценти не відповідав терміну вагітності, відзначалися набряклість, кісти та інфаркти плаценти, висока частота дифузних змін плацентарної тканини, гіперехогенні включення в навколоплідних водах. Звертає на себе увагу підвищення індексу резистентності в маткових артеріях, особливо у вагітних із субклінічним гіпотиреозом. Зі збільшенням терміну гестації периферичний опір мікросудинного русла плаценти підвищується у зв’язку з інволюційно-дистрофічними змінами та циркуляторними розладами, що дозволяє розробити критерії прогнозування та діагностики плацентарної дисфункції, попередити перинатальні порушення у вагітних із тиреопатіями.
Mental disorders as symptoms of brain tumors (literature review)
Authors: Yevtushenko N.Yu. , Zotov O.S.
Published: August 2024

Brain tumors can cause a variety of psychiatric symptoms, which can manifest in changes in the affective sphere, behavior, and cognitive abilities. These are called neuropsychiatric symptoms, also known as neurobehavioral symptoms. The most frequent psychiatric manifestations of brain tumors are depressive episodes, anxiety disorders, panic attacks, personality changes, psychotic episodes, memory deficiency, mania, auditory and visual hallucinations, eating disorders. If untreated timely, neuropsychiatric symptoms can have a significant impact on patients’ quality of life and survival. In extreme cases, these changes can lead to situations when the patient, due to changes in behavior, may pose a threat to himself and others. However, timely screening for psychiatric disorders in brain tumors allows for timely development of a set of measures to provide patients with palliative care. The purpose of this article is to review the association of psychiatric disorders in patients with brain tumors and to describe the way they can manifest
Випадок міграції силікону в аксилярні лімфовузли після розриву імпланта молочної залози
Authors: Cheshuk V.E. , Kropelnytskyi V.O. , Novokhatska L.V.
Published: August 2024

У статті описаний випадок міграції силікону після розриву силіконових імплантів молочних залоз в аксилярні лімфатичні вузли. У літературі описують силіконові утворення після розриву імплантів нечасто, така статистика відсутня. Через те, що після порушення цілісності імпланта в більшості випадків його видаляють одразу, міграція силікону в лімфатичні вузли не відбувається. У цьому випадку пацієнтка довгий час (2 роки) не зверталась по допомогу після розриву імплантів, і лише коли виявила ріст лімфатичних вузлів в аксилярній ділянці ліворуч, звернулась до спеціалістів. Було проведено обстеження молочних залоз — МРТ-мамографія з контрастом, яка підтвердила розриви по нижньолатеральній поверхні. Виконали видалення імплантів, часткове видалення капсули і реконструкцію молочних залоз більшими, ніж попередні, імплантами. Одужання без ускладнень. Естетичний вигляд задовільний. Висновок: тактика видалення розірваних імплантів, фіброзної капсули навколо них та препекторальної реконструкції грудних залоз новими імплантами може бути цілком виправданою в окремих випадках.
Spectrophotometry Based Oxidative Coupling Method for Determining Thymol Utilizing a Coupling Agent
Authors: Zayan Batool Mansour , Humeidy Israa Talib , Abdel Aziz Mohammad Salim
Published: August 2024

Developing a spectroscopic approach to assess the medicinal substance thymol was one of the research's objectives. Using an oxidative coupling reaction between thymol solution and N,N-dimethyl-p-phenylenediamine dihydrochloride solution (N,N-DMPPDADH) in alkaline media with potassium periodate as an oxidizing agent, the current technology forms a blue-colored soluble product. The wavelength at which a colored product exhibits maximum absorption is 600 nm. According to Beer's law, the concentration range covered by the approach under review is 1.25–20.00 μg/mL of thymol. The specific molar absorbance value of 10725.71 L/mol cm indicates the method's sensitivity. The Sandell significance value was 0.014 μg/cm2, which represents sensitivity per unit length. The precision of the method is demonstrated to be commendable, and the low relative standard deviation value of 0.16% supports this. This method's accuracy in identifying thymol at such low quantities is demonstrated by its confirmed detection limit of 0.0124 μg/mL. The developed technique has been useful in screening thymol in pharmaceutical products, with mouthwash being the focus of particular attention. Thymol content in real-world samples was accurately determined using the approach, as evidenced by the reported 101.13% recovery rate of thymol in the examined samples.
Synthesis and Adsorption of Alginate and Starch-Based Hydrogels for Cationic Dye from Aqueous Solution: Thermodynamic and Isotherm Modeling Non-linear
Authors: Aljeboree Aseel Mushtaq , Alkaim Ayad Fadhil
Published: August 2024

This work prepared new eco-friendly biocomposite hydrogels by graft co-polymerization from starch (ST), sodium alginate (SA), acrylamide (AM), and acrylic acid (AC). The performance of starch graft-poly(acrylamide-co-acrylic acid) (ST-g-P(AM-co-AC)) and sodium alginate graft-poly(acrylamide-co-acrylic acid) (SA-g-P(AM-co-AC)) absorbent hydrogels was evaluated for efficient dye removal from aqueous solution due to their unequal network structure and a restricted number of the hydrophilic groups. Adsorption characteristics of the as-prepared hydrogels were tested for methylene blue (MB) as an adsorbate. The removal percentage increases when increased the adsorbent doses of both hydrogels due to the increase of active sites of the hydrogel. The isotherm models and thermodynamic studies of MB dye on hydrogels have been assessed at several conditions like adsorbent dosage, solution temperature, and equilibrium time. The equilibrium results followed the Freundlich model. The thermodynamic parameter indicated that MB dye adsorption on hydrogels was endothermic and spontaneous. On the basis of the obtained result, the hydrogels are environmental and expansive adsorbent that might be a reliable alternative to elimination dyes from aqueous solution.
Cloud Point Extraction Method for Spectrophotometric Determination of 3-Aminophenol in Environmental Samples
Authors: Imran Alaa Mousa , Dhahir Saadiyah Ahmed , Muklive Ahmed Jassim
Published: August 2024

This work describes the development of new spectrophotometric techniques for 3-aminophenol assessment. The first technique involves using benzidine in an alkaline solution to convert 3-aminophenol into a colored complex. The produced complex has a red color with an absorbance of 462 nm. Between the concentration range 5–14 μg mL−1, Beer's law is obeyed with a correlation coefficient (R2) of 0.99781, a limit of detection (LOD) of 0.0423 μg mL−1, and a limit of quantification (LOQ) of 0.1411 μg mL−1. The recovery was between 87.2–95.43%, the relative standard deviation (%RSD) was 2.40–3.31% and the molar absorptivity was 3.545 × 103 L mol−1 cm−1. Secondly, cloud point extraction (CPE) was used to determine a trace amount of the colored product in the first method, followed by measuring with a UV-vis spectrophotometer. The linearity of the calibration curve was above the range of 5–14 μg mL−1, and the R2 was 0.9988. The LOD and LOQ were found to be 0.0318 and 0.1059 μg mL−1, respectively. The recovery was between 99.49–99.82%, the %RSD was 0.67–2.00% and the molar absorptivity was 4.724 × 103 L mol−1 cm−1. This method was successfully employed for 3-aminophenol detection in several wastewater samples from Rustamiya, under the Al Doura and Diyala bridge.
Clitoria ternatea Increases Milk Production in Dairy Cows by Inhibiting Dopamine Receptor D2: A Computational Study
Authors: Leondro Henny , Hadiani Dimas Pratidina Puriastuti , Krisnaningsih Aju Tjatur Nugroho , Lestari Oke Anandika , Wahyudi Didik , Gusmalawati Dwi , Tribudi Yuli Arif , Prihandini Peni Wahyu
Published: August 2024

Dairy cow's milk is a primary commodity in various countries and increasing milk production in dairy cows is crucial. Clitoria ternatea has the potential to enhance milk production in dairy cows. This research aims to analyze C. ternatea's ability to induce milk production in dairy cows by targeting the DRD2 protein. The compounds within C. ternatea were screened for drug-likeness, toxicity, physicochemical properties, and membrane permeability parameters. The DRD2 protein in dairy cattle was modeled using homology modeling. The interaction stability between C. ternatea compounds and DRD2 was analyzed through molecular docking and dynamic using AutoDock Vina and Webgro. The study results revealed that among the 18 compounds, 5 passed the drug-likeness screening: citronellal, alpha-terpinolene, 15-methyxypaysine, allyl-crotyl-zinc, and 9,12-octadecadiynoic. These 5 compounds exhibited low toxicity and demonstrated easy penetration of lipid membranes. Molecular docking results indicated that citronellal and alpha-terpinolene had the lowest binding energy values and were bound to the inhibitor's side. Molecular dynamic simulations also confirmed the stability of the interaction between citronellal and alpha-terpinolene with DRD2. In conclusion, this research suggests that C. ternatea can potentially increase milk production in dairy cows by inhibiting the DRD2 protein, primarily through citronellal and alpha-terpinolene.
Screening of Potential Compounds in Tomato (Solanum lycopersicum) as Candidates for Anti Diabetes Mellitus Complications
Authors: Narwasthu Sekararum , Fahmi Muhamad , Kurnianingsih Nia , Wihastuti Titin Andri , Fatchiyah Fatchiyah
Published: August 2024

This study aimed to identify the potential of natural compounds in tomatoes for diabetic complications intervention using amino acid profile, HP-TLC, antioxidant assay, enzymatic inhibitor assay, and in silico approach. Fresh air-dried tomatoes were analyzed for several screening assays including amino acid determination, HP-TLC, antioxidant activity using FRAP, α-amylase, and α-glucosidase enzyme inhibition. Virtual screening, molecular docking and molecular dynamics were performed using Molinspiration, pKcSM, AutoDock Vina, Discovery Studio, PyMOL, and Yasara software. Tomato bioactive compounds showed promising drug-likeness, antioxidant and α-amylase/glucosidase inhibitory activities, and potential for AGE-RAGE interaction. Out of 19 compounds from whole tomatoes complying with Lipinski’s rule of five, genistein, apigenin, and naringenin exhibited high oral absorption potential. Tomato contains genistein compound based on HP-TLC and the compound has high antioxidant and antidiabetic activities. Genistein has a stronger binding affinity with RAGE compared to AGE, indicating its potential as a competitive inhibitor. Additionally, genistein displayed stable ligand movements and higher binding energy values in MD simulations compared to the control. These findings suggest the potential of tomato bioactive compounds for further development as antidiabetic agents targeting AGE-RAGE interaction. In conclusion, genistein in tomatoes is indicated as a candidate for anti-complications of diabetes mellitus.
Strong Anisotropic Rashba Effect with Tunable Spin-Splitting in Two-Dimensional Janus Vanadium Dichalcogenides Monolayer
Authors: Affandi Yusuf , Absor Moh. Adhib Ulil , Anshory Muhammad , Amalia Wardah
Published: August 2024

Motivated by the recent discovery of the Rashba effect in two-dimensional (2D) Janus Transition Metal Dichalcogenides (TMDs) systems, we explore the Rashba effect on the Janus VXY (X = S, Se, Y = Se, Te) monolayer. By employing first-principles density functional theory (DFT) calculations, we find a strong anisotropic Rashba splitting observed around Γ points in the first Brillouin zone. We analyze this anisotropy of Rashba splitting by using k·p perturbation theory synergized with group symmetry analysis. By giving the effect of the biaxial strain, we manipulate the characteristics of the Rashba splitting on the Janus Vanadium Dichalcogenides system. Through spin texture analysis, we reveal both the in-plane and out-of-plane components of the spin textures, providing further evidence for the anisotropic nature of the Rashba spin-orbit coupling (SOC). The observed tuneable Rashba splitting by applying the strain effect shows that the Janus Vanadium dichalcogenides system has the potential to be used as a semiconductor material for spintronic devices.
Doping TiO2 with Cr and Cu Elements from Electroplating Wastewater as a Single Source for Improvement of the Photocatalyst Activity under Visible Light in the Degradation of Anionic Surfactant
Authors: Wahyuni Endang Tri , Budi Sulistyaning , Aurellia Dea , Widianti Rizky Aprilia , Lestari Novianti Dwi , Jaafar Nur Farhana , Suherman Suherman
Published: August 2024

This paper discusses the use of electroplating wastewater containing Cr and Cu as a single dopant source to improve the activity of TiO2 photocatalysts under visible light. Sol-gel doping was used to dop TiO2 with Cr and Cu in the wastewater. The doped TiO2 photocatalysts were characterized using SRUV/visible and XRD instruments, and their effect on the degradation of linear alkyl benzene sulphonate (LAS) in laundry wastewater was evaluated. The electroplating wastewater used in this research contains Cr and Cu about 2000 and 20 mg/L, respectively. These metals were successfully doped into a TiO2 structure, which significantly reduced the gap energy of TiO2, allowing it to be more active under visible light. The highest photodegradation of the 125 mg/L LAS in 25 mL of the laundry wastewater with pH 7 was achieved by using 30 mg of TiO2/Cr-Cu (200/2) photocatalyst, which degraded up to 60% of LAS in 60 min. With the same conditions, the LAS photodegradation increased to 100% upon the second run. This approach can help turn hazardous electroplating wastewater into a valuable material to solve environmental problems.
Risk Factors for Cannabis Use-Related Consequences in Emerging Adults
Authors: Samardzic Tamara , Soulliere Berlyn , Sagar Sanya , Miller Carlin J.
Published: August 2024

Cannabis use in Canada is a public health concern, especially it has been legalized for medical and recreational use. Although widely used, it appears there are negative consequences for some, but not all, cannabis consumers, and it remains challenging to predict which individuals will experience difficulties. This study examines the role of several risk factors in predicting negative outcomes of cannabis use in university students with a particular focus on personality and mental health variables. Undergraduate students (N=370) enrolled in a southwestern Ontario university participated in an online study. Preliminary analyses suggested that higher stress and lower conscientiousness were associated with cannabis use. In follow-up analyses, perceived stress was significantly associated with functional consequences of cannabis use when the quantity of cannabis used was accounted for in the analyses. Agreeableness and conscientiousness were significantly associated with overall GPA after controlling for amount of cannabis used. Individuals using low-to-moderate levels of cannabis had fewer functional consequences than individuals using higher amounts of cannabis, but these groups could not be differentiated in terms of their overall GPA. These results address a niche in the field of cannabis research in higher education and have significant implications in terms of policy and clinical practice.
Water quality assessment in the coastal zone of Campeche, southeastern Gulf of Mexico
Authors: Poot-Delgado Carlos Antonio , Rendón-von Osten Jaime , Okolodkov Yuri B. , Lara-Flores Maurilio
Published: August 2024

The purpose of this study was to assess the water quality at several sites with anthropogenic impact in the southeastern Gulf of Mexico. Eight sites at 3 coastal localities with different kinds of anthropogenic activity were monitored in September and November 2016. Water temperature, salinity, pH, dissolved oxygen, inorganic nutrients, heavy metals in sediments, fecal coliforms and phytoplankton abundance were determined. The pH values and the dissolved oxygen suggested a predominance of photosynthetic activity. Elevated nutrient contents were associated with sites of rainwater discharge with anthropogenic activities, as well as with biogeochemical processes. Inorganic nutrients, especially ammonium, nitrites and nitrates, heavy metals, and phytoplankton abundance showed influences of anthropogenic factors and can be considered indicators of water quality, although fecal coliforms (up to 900 Most Probable Number 100 mL-1) were not a good indicator of fecal contamination. The Nanoflagellates were the most abundant, followed
by diatoms. The non-toxic diatom Cylindrotheca
closterium, known to be a bloom-forming species,
and the harmful cyanobacterium Trichodesmium sp.
showed proliferations on the order of 105 cells L-1.
These phytoplankton responses are indicative of
the eutrophication due to fluctuations in environmental conditions because of the intensity and type
of human activities that take place in the study area.
Intervención multidisciplinar en un varón con trastorno por atracón: Estudio de un caso
Authors: Valdez Aguilar Mariana , Vazquez-Arevalo Rosalia , Mancilla-Diaz Juan Manuel
Published: August 2024

Objetivo: Evaluar la factibilidad de una intervención multidisciplinar (psicológica,  nutricional y actividad física) en línea en un  hombre con trastorno por atracón (TPA).
Método: Recibió el tratamiento un varón de 24 años de edad con TPA desde los 18 años. La intervención consistió en 24 sesiones de dos horas a la semana en las que se abordó contenidos de psicoeducación, inteligencia emocional y modificación del estilo de vida. Se aplicaron instrumentos psicométricos y medidas antropométricas a través de tres momentos de evaluación: pre, post y un seguimiento dos meses después.
Resultados: Hubo una disminución mayor al 20% de la frecuencia de atracones y de la sintomatología de ansiedad y depresión. En cuanto a la inteligencia emocional se observó mejoró  tanto en la post evaluación como en el seguimiento.Respecto a los hábitos alimentarios, el paciente disminuyó su consumo de cereales, grasas y azúcares y aumentó la ingesta diaria de frutas y verduras, además introdujo  la actividad física en su rutina diaria.
Discusión: El tratamiento fue efectivo en las variables clínicas intervenidas, lo que implica la posibilidad de abordar el trastorno de manera integral y personalizada, prevenir recaídas y mejorar la calidad de vida del paciente a largo plazo. Los hallazgos son relevantes ya que es uno de los primeros estudios de tratamiento en México y sobretodo en hombres, ayudándolos en el reconocimiento del vínculo emoción y alimentación.
Propiedades psicométricas de los autoreportes de ingesta emocional: Una revisión sistemática
Authors: Vázquez Vázquez Vanessa Monserrat , Franco-Paredes Karina , Díaz-Reséndiz Felipe de Jesús , Bosques-Brugada Lilián Elizabeth , Tovar-Garza Erin Yaqueline
Published: August 2024

El interés por la ingesta emocional (IE) ha ido en aumento, así como el número de autoreportes que permiten evaluarla. El objetivo de la presente investigación fue realizar una revisión sistemática de la calidad psicométrica de los autoreportes de IE en población adulta (PROSPERO ID: CRD42022374665). La búsqueda se realizó en PubMed, Web of Science, Scopus, Springer link, Taylor & Francis, Science Direct e identificación manual considerando los lineamientos PRISMA. La calidad metodológica y de las propiedades de medida fueron evaluadas a partir de los estándares y criterios COSMIN. Fueron analizados nueve autoreportes que denotaron discrepancias conceptuales y que en su mayoría se trataron de escalas multidimensionales. Las principales evidencias de validez reportadas fueron la estructural (a través de análisis factorial exploratorio o análisis de componentes principales) y de constructo, en menor medida, algunos artículos realizaron procedimientos cualitativos como parte de la validez de contenido. En tanto a la confiabilidad, el procedimiento más empleado fue el análisis de consistencia interna (α = .77 - .94) y en menor medida la estabilidad temporal. La Positive-Negative Emotional Eating Scale y la Salzburg Emotional Eating Scale obtuvieron mejores calificaciones respecto a su calidad metodológica y métrica. Las mayores deficiencias identificadas en los autoreportes fueron respecto a la validez de contenido, lo que pone en evidencia la necesidad de fortalecer esta propiedad métrica, así como la validez estructural y la consideración de otras poco o nulamente reportadas.
Implementing Scalable Solutions for Space Debris Mitigation
Authors: Aneja Ameya
Published: August 2024

Abstract: Collision of space debris present in the LEO (Low Earth Orbit) poses a serious threat to the current operational space missions as well as to the future utilization of the LEO space. These also result in major environmental impairment and significant economic losses due to damage to satellites and space stations. It thus becomes imperative to develop effective strategies and design and build systems which can aid in the removal of both small and large debris. This paper investigates the various existing space debris mitigation models such as ElectroDynamic Debris Eliminator (EDDE), ESA’s Space Harpoon, Laser Ablation, and JAXA’s Electrodynamic tether. A useful comparison is drawn amongst these different techniques while evaluating their efficiency within the framework of methods for space debris capture and removal. The advantages and drawbacks of these technologies are discussed through examples, previous and ongoing projects. The paper also aims to briefly introduce a novel concept for debris mitigation and to motivate more rigorous research in this area
Efecto del aprovechamiento forestal en la formación de madera en árboles remanentes de Abies religiosa
Authors: Rojas-García Fabiola , Gómez-Guerrero Armando , Terrazas Teresa , Endara-Agramont Angel , Gutiérrez-García Genaro , Reyes-Hernández Valentín , Ángeles-Pérez Gregorio , De Jong Bernardus
Published: August 2024

El manejo forestal puede modificar la estructura y la calidad de la madera. En este estudio se evaluó el efecto de un aprovechamiento forestal sobre la formación de madera en árboles remanentes. En un bosque de Abies religiosa (oyamel) intervenido con un aclareo del 50 % de área basal durante 2014, se inventariaron 10 sitios de muestreo (1000 m2). Se analizaron mediante técnicas dendrocronológicas 80 núcleos de crecimiento provenientes de 40 árboles remanentes. Se evaluó la microdensidad y las características celulares de la madera tardía. Los anillos de crecimiento de Abies religiosa (oyamel) presentaron una buena delimitación entre madera temprana y madera tardía en la cronología de 90 años desarrollada. El aprovechamiento forestal incremento en 42,4 % el ancho de anillo; la microdensidad varió de 189 kg·m-3 a 417 kg·m-3 ( = 335 kg·m-3); las traqueidas presentaron una disminución de 8,02 % en el espesor de la pared celular y el diámetro del lumen aumento un 29,8 %. Se identificó una fila de canales traumáticos fechada en 2014, posiblemente relacionados con el estrés de la corta. Las modificaciones en la anatomía de la madera causaron una variación en la microdensidad de la madera, que repercute en la cuantificación volumétrica y de biomasa a nivel del rodal.
Improved Pairwise Measurement-Based Surface Code
Authors: Grans-Samuelsson Linnea , Mishmash Ryan V. , Aasen David , Knapp Christina , Bauer Bela , Lackey Brad , Silva Marcus P. da , Bonderson Parsa
Published: August 2024

We devise a new realization of the surface code on a rectangular lattice of qubits utilizing single-qubit and nearest-neighbor two-qubit Pauli measurements and three auxiliary qubits per plaquette. This realization gains substantial advantages over prior pairwise measurement-based realizations of the surface code. It has a short operation period of 4 steps and our performance analysis for a standard circuit noise model yields a high fault-tolerance threshold of approximately 0.66%. The syndrome extraction circuits avoid bidirectional hook errors, so we can achieve full code distance by choosing appropriate boundary conditions. We also construct variants of the syndrome extraction circuits that entirely prevent hook errors, at the cost of larger circuit depth. This achieves full distance regardless of boundary conditions, with only a modest decrease in the threshold. Furthermore, we propose an efficient strategy for dealing with dead components (qubits and measurements) in our surface code realization, which can be adopted more generally for other surface code realizations. This new surface code realization is highly optimized for Majorana-based hardware, accounting for constraints imposed by layouts and the implementation of measurements, making it competitive with the recently proposed Floquet codes.
Pemanfaatan Buah Buni (Antidesma Bunius (L. Spreng) dalam Produk Olahan Minuman Wine Kaya Antioksidan
Authors: Purnamasari Gusti Agung Ayu Nirmala , Purnantara I Made Hadi
Published: August 2024

Pemanfaatan merupakan suatu kegiatan, proses, cara atau perbuatan menjadikan sesuatu yang sudah ada menjadi lebih bermanfaat atau dengan kata yaitu berfaedah. Salah satu produk olahan minuman yang sudah dikenal luas dan terkenal di kalangan masyarakat adalah Wine. Wine adalah minuman berakohol yng dhasilkan dari hasl fermentasi buah - buahan yang sudah dihancurkan dan diambil jus buahnya saja untuk difermentasi menjadi wine. Slah stu buah yang sering digunakan sebagai bahan baku pmbuatan wine adlah buah anggur, oleh karena itu penulis tertarik untuk mencoba dan mengetahui pemanfaatan wine berbahan dasar buah buni sebagai pengganti buah anggur dalam pembuatan wine pda umumnya. Tjuan dri penelitiian ini adalah untuk mengetahui bagaimana perbandingan wine berbahan dasar buah buni dilihat dari segi warna, rasa, aroma, tekstur, penampilan, daya tahan, minat beli konsumen dan biaya produksi. Dalam data ini menggnakan analisiis ujii organoleptiik dengann responden sebanyak 30 pnelis. Dengan daya tahan wine buah buni ini dapat bertahan selama 1 bulan dalam suhu ruang dan dapat bertahan selama kurang lebih 2 bulan jika diletakan dalam chiller atau suhu berpendingin. Sedangkan biaya produksi dalam pembuatan wine berbahan dasar buah buni adalah Rp 65.000.
 
Utilization is an activity, process, way or action to make something that already exists more useful or in the word useful. One of the processed beverage products that is widely known and famous among the public is Wine.  Wine is a alcoholic beverage produced from the fermentation of fruits that have been crushed and taken only fruit juice to ferment into wine. One fruiit that is often used as raw materiial for winemaking is grapes, therefore the author is interested in trying and knowing the use of wine made from grapes as a substitute for grapes in winemaking in general. The purpose of this study is to find out how the comparison of wine made from buni fruit in terms of color, taste, aroma, texture, appearance, durability, consumer buying interest and production costs. In thiis data using organoleptiic test analysiis with respondents as many as 30 pnelists. With the durability of this bean fruit wine can last for 1 month at room temperature and can last for approximately 2 months if placed in a chiller or refrigerated temperature. While the production cost in making wine made from buni fruit is Rp 65,000.
Б.Дэмчигдорж монгол хэл судлаач болох нь
Authors: Jantsan Bat-Ireedui
Published: August 2024

In the history of Mongolian linguistics, many people have studied the Mongolian language and linguistics, but some people are not well known by the public. One of them is Demchigdorj Baljirtündev, who was in charge of Mongolian language affairs at the Ministry of Enlightenment (Education) of Mongolia in 1960 and was also researching the modern Mongolian language. Heritage and documentary materials related to the life and research work of this person have recently been registered in the fund of our institute, and based on those materials, this article is being written in order to clarify and inform about the research done by this person in the Mongolian language.
Миньхэ монгор хэлний *ki- үйл үгийн түүхэн хувьслын тухай орчин цагийн монгол хэлний байдалтай харьцуулан үзэх нь
Authors: Shiotani Shigeki ,   Osaka University
Published: August 2024

This paper considers the development of the verb *ki- (to do) in the Minhe Monguor language from a diachronic perspective, compared with Modern Mongolian. As a result of the research, *ki- (to do) became ge- [gǝ-] as a simple word and -ke- [-kǝ-] as the denominal verbal suffix in forming verbs from words of Chinese origin. Moreover there is another alternation of the suffixes -ke- [-kǝ-] ~ -qi- [-ʨi-] which men tend to use more often. In other words these three morphemes have the same origin *ki- and the phonological changes can be explained as occurring in the order 1.*ki- > -ke- [-kǝ-] (voiceless), 2.*ki- > -qi- [-ʨi-] (palatalized), and 3.*ki- > ge- [ɡǝ-] (voiced) etc. Finally, the similarities and differences between two languages were mentioned in the conclusion.
REMOVAL OF MERCURY (Hg) FROM TAILINGS WASTE CONTAMINATED SOIL BY PHYTOREMEDIATION USING VETIVER (Vetiveria zizanioides L.)
Authors: Bayani Hartila , Hamdan Abd Mujahid , Hidayat Muslich
Published: August 2024

Mercury waste from unlicensed gold mining (PETI) is absorbed by the soil, so that the soil contains Mercury (Hg). This will cause environmental pollution. The Hg waste treatment method using the phytoremediation method has been able to bind Hg contained in the soil. However, phytoremediation of Hg waste from tailings soil using vetiver plants (Vetiveria zizanioides L.) has never been specifically studied. This study aims to determine the removal of Hg from soil contaminated with traditional gold mining tailings waste to determine the effect of Hg levels in the soil on the growth of Vetiveria zizanioides L. Vetiveria zizanioides L. plants in the soils that previously had heavy metal Hg as a pollutant with concentration variations of 1.8816 ppm and 1.9113 ppm and harvest variations of 7, 14, and 21 days. The results showed that Vetiveria zizanioides L. can accumulate Hg in the roots, soil, and leaves. The highest Hg accumulation in the roots of all types of concentration variations of 1.8816 ppm and 1.9113 ppm were 1.52 µg/g, 1.52 µg/g and 1.32 µg/g; 1.254 µg/g, 0.6813 µg/g and 0.59 µg/g on stems; while 1.02 µg/g, 0.49 µg/g and 0.04 µg/g on the soil. From the data that has been presented, it can be seen that the sample of Vetiveria zizanioides L. is able and effective in reducing the concentration levels of contaminants contained in tailings waste soil. The results of a simple linear regression test for Hg waste treatment showed that there was an effect of time/day on the decrease in the levels of the test parameters. The results indicate the use of Vetiveria zizanioides L has the potential to be used in the treatment of Hg-contaminated waste soil.
Comparison of Tracking Calculation Method of Solar Eclipse and Al-Durru Al-Anîq in Local Solar Eclipse
Authors: Farih Al Husna Muhammad
Published: August 2024

Tracking solar eclipses is a method for calculating local solar eclipses written by Muhammad Wasil. The method that has been outlined in this program is said to have a high level of accuracy. Another method that has been recognized for its level of accuracy is the creation of K.H. Ahmad Ghozali in the book al-Durru al-Anîq. Even though both methods are classified as contemporary reckoning, differences in the algorithms will result in differences in the final results. This is the basis for studying the two methods to find out the specifications of the differences in the algorithms used, as well as knowing how far the difference in the calculation results is. This research examines it using a comparative analysis approach. As a result, the differences in the two methods include the data input source, stages and formulas used, as well as differences in the final calculation results, which range from 0 to 29 seconds.
The distribution of shoulder enhancement and associated features among NEIALs spectra observed with the EISCAT Svalbard 42m radar
Authors: Bashkim DALIPI  , SYLA Naim , Fisnik ALIAJ  , Donat DALIPI  , Arbër ZEQIRAJ
Published: August 2024

Reports link NEIALs phenomena to ionospheric plasma processes, yet their full understanding remains unexplored. One of the reasons is that the plasma analysis using the Grand Unified Incoherent Scatter Data Analysis Program (GUISDAP) fails on occasions when these phenomena occur. However, we can evidence some aspects of the spectra, such as appearance, morphology, frequency of occurrence, and spectrum features, by analyzing the raw data using the Real-Time Graph (RTG) program. We obtained these data using the 42-meter EISCAT Svalbard radar. This article talks about the features of NEIALs, such as their spectral shape, enhanced spectral signatures, altitude distribution of spectral enhancement, frequency of NEIAL occurrence, maximum power returned, shoulder asymmetry enhancement, and frequency shift of the whole ion line spectrum. Additionally, we have discussed NEIALs characteristics related to specific ionospheric E and F regions.
Hydrolysis With Two Enzymes in Edible Fern (Diplazium esculentum) as a Source of Flavours
Authors: Kartikasari Subekah Nawa , Witono Yuli , Handoyo Tri , Santoso Umar
Published: August 2024

Abstract- Ferns (Diplazium esculentum) play a significant economic and ecological role in certain areas. They are one of the forest vegetables that grow in cool and humid air or tropical forests, often cultivated by people or growing wild. Ferns are popular due to their high levels of vitamins, minerals, protein, and fat, as well as their abundance in production, chemical-free nature, cheapness, unique flavor, and chewy taste. They can be processed as vegetables and have the potential to be developed as a healthy flavor source from vegetables as a substitute for MSG. Currently, there is a lack of knowledge about the technology for processing fern flavors and the potential health benefits of ferns.
 
Keywords: Glutamic acid, bromelain enzyme, flavor, protease (biduri).
Creative Food Product of Healthy Puffed Riceberry Snack Bar Developed by Private-Community-University Collaborations
Authors: Panyoyai Naksit , Wattanakul Watcharapong , Suwannalers Piluntasoot , Bunsongthae Akharasit , Khumcharoen Sakunrat , Kaima Prakaydao , Prompratan TongMed , Kaewyodkong Wannipa
Published: August 2024

“Riceberry” a variety cultivated for its high anthocyanin content, offers bio-functional benefits. The development of Riceberry products not only enriches the nutritional profile but also adds a creative dimension to the One Tambon One Product (OTOP) initiative of Thailand. The collaborative effort of Hin Kling, a community enterprise in Nakhon Sawan, Chiang Mai Rajabhat University (CMRU), and the support from the Petroleum Authority of Thailand (PTT) Public Company Limited, has been instrumental in this venture. Adopting the Four Ps model (process, product, packaging, and product marketing), the collaboration focused on refining production processes, ensuring product quality, providing informative packaging, and devising effective marketing strategies. The study revealed that saturated fat content was reduced by two-fold through the innovative approach of blending palm oil with soybean oil for frying puffed rice. The resulting puffed rice was then combined with various ingredients and shaped into bars, offering a product with a commendable shelf life of up to three months. Moreover, a commitment to health was demonstrated by reducing the added palm sugar, leading to lower sugar content, reduced calories, and improved texture in the healthier product. Rigorous quality checks, including water activity value, anthocyanin content, and total and pathogenic bacteria count, ensured that the product met the standards set for cereal bars. To enhance consumer awareness, the product's nutritional value was highlighted through a detailed nutritional facts section on the food label. Additionally, a captivating community story was crafted to introduce the health-focused product to the wider health food market. The three-party collaboration behind the Riceberry initiative has successfully delivered a bio-functional, nutritious, and creatively presented product tailored for health-conscious consumers.
Impact of Pomegranate Peel (Punica granatum L.) Extract on Rice Starch-Pectin-Based Films for Maintaining the Organoleptic Properties of Tomatoes
Authors: Laramli Nurraihanah Kamilia , Supri Sarifah , Wen Xia Felicia Ling , Afifah Jauharotul , Maimunah Yunita , Rovina Kobun
Published: August 2024

Pomegranate peel (Punica granatum L.) is commonly disregarded as a byproduct in the juice industry despite its rich content of bioactive compounds. This study investigates the impact of incorporating pomegranate peel extract at concentrations of 0%, 1%, 2%, and 3% into rice starch-pectin-based films. Characterization of the films was conducted using Fourier Transform Infrared Spectroscopy (FTIR) and Field Emission Scanning Electron Microscopy (FESEM). Physicochemical properties including thickness, color, opacity, moisture content, water solubility, and water vapor permeability were assessed. The results demonstrate that the incorporation of pomegranate peel extract significantly enhanced the properties of the rice starch-pectin-based films (p < 0.05). Moreover, antimicrobial assays revealed substantial inhibition of Escherichia coli by films containing 3% pomegranate peel extract. Furthermore, the efficacy of these films was evaluated using real tomato samples to assess their potential to extend the shelf life of perishable foods. The findings suggest that the inclusion of pomegranate peel extract in the film matrix contributes to natural pigment preservation, mitigates microbial contamination, and maintains the organoleptic attributes of tomatoes, thereby potentially enhancing their shelf life. These results underscore the promising applications of pomegranate peel extract in the development of sustainable and functional food packaging materials.
Characteristics of Isothermic Sorption Curves and Determination of the Best Equation Model for Egg Flour
Authors: Syamsuri Riswita , Dirpan Andi , Laga Amran , Salengke Salengke
Published: August 2024

Egg flour storage is influenced by temperature, relative humidity, and water activity. Equilibrium of moisture content is closely related to sorption isotherm to determine optimal storage conditions. This research evaluated the characteristics of isothermic sorption curves and determined the appropriate equation model to describe isothermic sorption curves on various types of egg flour. The egg flour used is egg white flour, egg yolk flour, and whole egg flour (white and yolk), which is ohmic pasteurized for 5 minutes at 600C, then oven and vacuum dried. After that, the samples were stored in a desiccator with different humidity levels (10-80%) at a temperature of 300C. The desiccator is inserted into the incubator to maintain the temperature. This research used four equation models: Oswin, Chung-Pfost, Caurie, and Helsey. The results showed that the isothermic sorption curve of egg flour had a sigmoid absorption type, which reflected a Type II isothermic pattern. Based on the coefficient of determination (R2) and RMSE, the Oswin equation model is the most appropriate for describing the isothermic sorption pattern for all egg flour tested. This model can be used to predict optimal storage conditions for egg flour.
Análisis del grado de documentación del Sistema de Gestión de Seguridad y Salud en el Trabajo frente a la Resolución 1111 de 2017, de una empresa de construcciones de la ciudad de Cúcuta.
Authors: Piña Lerma Jattin Eslava , Vásquez Leguizamón Cecilia
Published: August 2024

Esta investigación permitió diseñar el Sistema de Gestión de Seguridad y Salud en el Trabajo basándose en el Decreto 1072 del 2015 en una empresa de construcciones para dar respuesta a la necesidad de establecer lineamientos claros sobre información documentada. Inicialmente, se realizó un diagnóstico para conocer el estado actual de la empresa. De la misma manera, se empleó la Guía Técnica Colombiana (GTC 45) para identificar los peligros y valorar los riesgos en Seguridad y Salud Ocupacional. Finalmente se tomó como referente el Decreto 1072 de 2015 para hacer la documentación de los requisitos mínimos legalesde un sistema de gestión. Todo esto con el fin de presentar un trabajo seguro en la empresa durante el desarrollo de sus actividades laborales,Esta investigación permitió diseñar el Sistema de Gestión de Seguridad y Salud en el Trabajo basándose en el Decreto 1072 del 2015 en una empresa de construcciones para dar respuesta a la necesidad de establecer lineamientos claros sobre información documentada. Inicialmente, se realizó un diagnóstico para conocer el estado actual de la empresa. De la misma manera, se empleó la Guía Técnica Colombiana (GTC 45) para identificar los peligros y valorar los riesgos en Seguridad y SaludOcupacional. Finalmente se tomó como referente el Decreto 1072 de 2015 para hacer la documentación de los requisitos mínimos legales de un sistema de gestión. Todo esto con el fin de presentar un trabajo seguro en la empresa durante el desarrollo de sus actividades laborales,Esta investigación permitió diseñar el Sistema de Gestión de Seguridad y Salud en el Trabajo basándose en el Decreto 1072 del 2015 en una empresa de construcciones para dar respuesta a la necesidad de establecer lineamientos claros sobre información documentada. Inicialmente, se realizó un diagnóstico para conocer el estado actual de la empresa. De la misma manera, se empleó la Guía Técnica Colombiana (GTC 45) para identificar los peligros y valorar los riesgos en Seguridad y Salud Ocupacional. Finalmente se tomó como referente el Decreto 1072 de 2015 para hacer la documentación de los requisitos mínimos legales de un sistema de gestión. Todo esto con el fin de presentar un trabajo seguro en la empresa durante el desarrollo de sus actividades laborales,utilizando la promoción de la salud y la prevención de la enfermedad y evitar la aparición de accidentes laborales y/o enfermedades profesionales que afecten el bienestar óptimo de los trabajadores.
Atuação fisioterapêutica no tratamento do Lúpus Eritematoso Sistêmico: revisão de literatura
Authors: Machado Moura Drielle , Luiz Albuquerque Vieira Renan , Galindo da Silva Moraes Lusicleide , Rezende Barreto Arihelli , Alvarenga Fachardo Oliveira Gilmara , Ribeiro de Souza Hanilton , Oliveira de Almeida Vanessa
Published: August 2024

Lúpus Eritematoso Sistêmico (LES) é uma doença inflamatória crônica, multissistêmica, de etiologia desconhecida e caráter autoimune, que provoca danos teciduais. O tratamento do Lúpus Eritematoso Sistêmico (LES) é desafiador devido à sua natureza multifacetada, e a fisioterapia emerge como uma importante ferramenta complementar. Diante do exposto, teve-se como objetivo geral analisar por meio de revisão de literatura os benefícios da fisioterapia no tratamento do LES. E objetivos específicos: Analisar a fisioterapia respiratória em pacientes portadores LES, descrever a fisioterapia no alívio da dor e destacar a atuação do (a) fisioterapeuta na melhoria da qualidade de vida dos pacientes com LES. A pesquisa baseia-se em revisão bibliográficas realizada nas bases de dados indexadas da Biblioteca Virtual em Saúde (BVS), Google Acadêmico, Scielo e PubMed. Com recorte temporal entre 2010 a 2020. Os descritores utilizados nas buscas foram: LES, doença reumática, tratamento fisioterapêutico. A partir da análise dos 11 artigos científicos utilizados para compor esta revisão, pôde-se notar que a abordagem fisioterapêutica consiste em uma intervenção ouro para o tratamento do LES, promovendo melhorias na qualidade de vida dos pacientes. Desta forma pode-se concluir que, por meio de intervenções fisioterapêuticas é possível alcançar melhora significativa no tratamento do LES.