bluuebunny/crossref_metadata_2025 huggingface dataset:
Best practices for teaching the concept of the derivative: Lessons from experienced calculus instructors
Authors: Mkhatshwa Thembinkosi Peter
Published: March 2024

Much research has reported on difficulties exhibited by students when working with the concept of the derivative in first-semester university calculus. In an effort to generate and share a resource on effective instructional practices related to the teaching of the concept of the derivative, a 12-item questionnaire was administered to experienced calculus instructors in the United States. Most of the 10 experts who participated in this study considered providing ample examples and practice problems, using graphing utilities such as Desmos and GeoGebra, and employing problem solving strategies in the teaching of the concept of the derivative to be effective in supporting students learn about the concept of the derivative, among other things. These experts further remarked on representations of the concept of the derivative and real-world contexts they typically use in their teaching of the concept, in addition to providing rationales for the choice of real-world contexts they typically use in their teaching of the concept. Recommendations for instruction are included.
Kauppatieteiden koulutus ja planetaarinen hyvinvointi
Authors: Aaltonen Valtteri
Published: March 2024

Väitöstilaisuuden aiheena on vastuullisuus kauppatieteiden koulutuksessa ja planetaarinen hyvinvointi tämänkin alan uutena päämääränä ja näkökulmana. Kauppatieteiden koulutuksella tarkoitan sitä kauppatieteiden kandidaatin ja – maisterin tutkintoihin tähtäävää koulutusta, jota tarjotaan kauppakorkeakouluissa eli yliopistoissa tai tiedekunnissa, joiden oppiaineita ovat muun muassa johtaminen ja organisaatiot, markkinointi, laskentatoimi, yrittäjyys, kansainvälinen liiketoiminta, rahoitus ja taloustiede. Planetaarinen hyvinvointi on käsite, joka viittaa elämän edellytysten prosesseihin ja planeetan erilaisten elämänmuotojen lajityypillisiin tarpeisiin näiden eri elämänmuotojen ja niiden asuttamien ekosysteemien keskinäisriippuvuudet huomioivalla tavalla.
Väitöskirjassani eli tässä puheenvuorossa väitän, että planetaariseen hyvinvointiin tähtäävä vastuullisuus kauppatieteiden koulutuksessa edellyttää autenttisuuden, organisoinnin rytmien ja prosessuaalisuuden tunnistamista ja soveltamista käytäntöön.
Valtteri Aaltosen väitöskirja ”Organising responsible management education: examining the processuality and possibilities towards planetary well-being” tarkastettiin 13.12.2023 Jyväskylän yliopistossa. Vastaväittäjänä toimi professori Pasi Heikkurinen (LUT yliopisto) ja kustoksena apulaisprofessori Marjo Siltaoja (Jyväskylän yliopisto). Tämä teksti perustuu Aaltosen väitöstilaisuuden lektioon. Väitöskirjaan voi tutustua osoitteessa: https://urn.fi/URN:ISBN:978-951-39-9853-0
Examinees’ Four Skills Performance Balance in High Stake Foreign Language Examinations
Authors: Venturis Antonio , Vaiopoulou Julie
Published: March 2024

The present study aims to investigate the balance of the examinees’ performances in different skills tests as part of a foreign language examination. In many cases, the examinees’ performances in the four skills present significant deviations. This deviation raises the question of whether it is an indication of an error in the construction or rating of the test or whether it is an expected result. In order to explore this question, a study was conducted using real data collected from 8715 candidates who participated in Italian language exams, administered by the Greek State Certificate Language Proficiency System (KPG), between 2011 and 2015 (ten sessions). The data were analysed with Latent Class Analysis (LCA) and indicated that there is no balance between the performances of the examinees in the different skills tests.
The Performance of Discus (Symphysodon discus) Hatchery in Joel Nararya Farm, Sukarame, Bandar Lampung
Authors: Santanumurti Muhammad Browijoyo
Published: March 2024

Indonesia has biodiversity in ornamental fish commodities. ). One of the ornamental fish that has the potential to be developed is the discus fish. The hatchery of discus fish is an important activity in the aquaculture process. This study aimed to determine the performance of discus fish hatchery in Joel Nararya Farm, Sukarame, Bandar Lampung. This study observed 2 broodstock of hatchery prouction, code A (Female Pigeon x Male Pigeon) and B (Female Pigeon x Male Blue Turqoise). This study showed that the fecundity was 153 eggs for A and 160 eggs for B. The fertilization rate showed a value of 73% for codes A and B. The hatching rate value indicated a value of 15% for code A and 64% for code B. The performance of discus fish hatchery was not optimum. The farm should use 2:2 ratio male and female to increase the eggs production. The code A hatchery aquarium was also too close to the passing places of broodstock so that they were easily stressed and affected the hatching rate. It need to be replaced to proper location.Â
PENGARUH PENGGUNAAN Ipomoea aquatica (KANGKUNG) PADA SISTEM CRS (Close Resirculation System) BUDIDAYA IKAN LELE DENGAN TEKNOLOGI FITOREMEDIASI
Authors: Saad Moch , Purnamasari Ika , Prihatini Endah Sih , Mas'ud Faisol
Published: March 2024

Akumulasi limbah tersebut dapat menyebabkan penurunan kualitas air yang berpengaruh terhadap proses fiiologis, tingkah laku, pertumbuhan, dan mortalitas ikan. Teknologi budidaya yang ramah lingkungan dan hemat air sangat dibutuhkan. Salah satu upaya pengelolaan untuk meningkatkan kualitas air dan mengoptimalkan pemanfaatan limbah air budidaya adalah dengan sistem fitoremediasi secara resirkulasi tertutup. Salah satu upaya pengelolaan untuk meningkatkan kualitas air dan mengoptimalkan pemanfaatan limbah air budidaya adalah menggunaan sistem fitoremediasi dengan resirkulasi tertutup. Tujuan penelitian ini adalah untuk mengetahui pengaruh penggunaan Ipomoea aquatica (kangkung) pada sistem CRS (close resirculation system) budidaya ikan lele dengan teknologi fitoremediasi teknologi yang efektif dan efisien. Metode penelitian yang digunakan adalah deskriptif kualitatif untuk menguji perbandingan antara budidaya lele tradisional, menggunakan sirkulasi serta menggunakan teknologi Ipomoea aquatica (kangkung) dengan sistem CRS (close resirculation system) budidaya ikan lele. Penelitian dilaksanakan pada bulan Mei hingga Juli 2021 di kelompok Pembudidaya Ikan â€œLestari Makmurâ€Â  di Desa Sambangan, Kecamatan Babat, Kabupaten Lamongan, Propinsi Jawa Timur. Berdasarkan hasil uji coba teknologi fitoremediasi menggunakan kangkung dengan sistem CRS (closed resirculation system) yang dibandingkan dengan tanpa menggunakan metode tersebut menunjukkan bahwa teknologi fitoremediasi menggunakan kangkung dengan sistem CRS (closed resirculation system) memberikan hasil yang positif dan lebih baik dalam meningkatkan kualitas budidaya ikan lele. Ikan lele yang dipelihara menggunakan teknologi fitoremediasi memperlihatkan kualitas air yang relatif baik dibandingkan tanpa menggunakan teknologi fitoremediasi, pertambahan bobot juga terlihat menunjukkan pola peningkatan yang baik dengan tingkat kelulus hidupan yang lebih tinggi dengan rata-rata 97%.
Evaluasi Kawasan Konservasi Laut Dengan Pendekatan Pressure State Response
Authors: Haryani Eny Budi Sri
Published: March 2024

Penelitian ini dilakukan di Kawasan Konservasi Laut (KKL) Raja Ampat, Provinsi Papua Barat, pada bulan Oktober 2019. Pada awal penetapan sebagai KKL tahun 2007, kondisi perairan Raja Ampat dipersepsikan baik, dengan keanekaragaman sumberdaya ikan (SDI) tinggi. Namun saat ini perlu dievaluasi, setelah 15 tahun sejak ditetapkan menjadi KKL. Tujuan penelitian ini untuk mengevaluasi kondisi KKL dengan pendekatan analisis PSR (pressure, state, response), dengan pengumpulan data primer dan sekunder. Data primer berupa persepsi masyarakat terhadap pengaruh adanya KKL terkait kondisi SDI, ekosistem dan sosial ekonomi masyarakat, dengan instrumen penelitian berupa kuesioner dan wawancara dengan purposive sampling terhadap responden, yaitu penangkap ikan, aktivis dan tokoh masyarakat, wisatawan dan penentu kebijakan setempat, menggunakan skala jawaban persentase (%). Data sekunder diperoleh dari dinas terkait berupa kondisi demografi, geografis dan sosial budaya. Hasil penelitian, di KKL Raja Ampat terdapat pressure (tekanan) berupa kesejahteraan masyarakat rendah, sumber mata pencaharian mengandalkan penangkapan ikan, aktivitas perikanan merusak dan illegal fishing dari nelayan pendatang, berkembangnya pariwisata bahari dan isu rencana penambangan di laut. State (kondisi eksisting) bahwa perairan belum rusak, jumlah kapal dan nelayan serta biaya melaut meningkat, harga ikan meningkat, kondisi terumbu karang dan mangrove lebih baik, dengan kesejahteraan meningkat dan KKL dianggap baik. Juga ketersediaan ikan semakin banyak, sehingga penangkapan ikan semakin mudah, walaupun area penangkapan ikan menjadi jauh, sehingga kesejahteraan masyarakat semakin baik. Response (tanggapan) dengan membuat regulasi pada skala desa atau kabupaten, yang fungsinya untuk menyelamatkan SDI, ekosistem pesisir dan kesejahteraan masyarakat.Â  Data isian kuesioner, bila diklasifikasi dengan kisaran, persepsi baik kisaran 50-90 % responden, suatu kondisi yang baik, sedangkan persepsi buruk/jelek dengan kisaran 0-20% responden. Saran kebijakan, bahwa response yang ada agar segera diatur dalam peraturan daerah, dan segera dibuat strategi pengembangan KKL Raja Ampat berdasarkan analisis PSR ini yang dilengkapi bioeconomic analysis danÂ  economic valuation, agar strategi pengembanganÂ  KKL lebih realistis, dengan dasar analisis ilmiah yang valid.Â
ANALISIS PENDAPATAN DAN RISIKO USAHA BUDIDAYA UDANG VANAME (Litopenaeus vannamei) DI DESA GLAGAH KECAMATAN GLAGAH KABUPATEN LAMONGAN
Authors: Purnamasari Ika , Ali Mukti , Habibullah A Fajar
Published: March 2024

Budidaya udang vaname meskipun mempunyai nilai ekonomis yang tinggi namun tidak terlepasresiko dan ketidakpastian.Sumber resiko dan ketidak pastian dalam usaha perikanan diantaranya fluktuasi hasil produksi, fluktuasi harga jual, biaya produksi yang tinggi, produktifitas yang rendah, kondisi alam yang tidak dapat diprediksi dan lain sebagainya yang akan mempengaruhi hasil pendapatan. Tujuan penelitian yaitu menganalisis besarnya pendapatan dan risiko usaha budidaya udang vaname di Desa Glagah, Kecamatan Glagah, Kabupaten Lamongan. Metode analisis pertama yang digunakan adalah analisis pendapatan. Metode analisis yang kedua yaitu analisis resiko menggunakan ukuran ragam atau simpangan baku dan koefisien variasi (CV).Hasil penelitian menunjukan bahwa rata-rata total biaya produksi usaha budidaya udang vaname dalam satu siklus produksi yaitu sebesar Rp14.696.687/Ha dan rata-rata penerimaan sebesar Rp 44.675.705/Ha sehingga keuntungan yang diperoleh pembudidaya sebesar Rp 29.979.018/Ha. Besarnya keuntungan tersebut diperoleh dari perkalian harga jual udang dan hasil produksi udang vaname, dimana hasil produksi udang vaname yaitu rata-rata 843,24 Kg/Ha dan harga jual Rp 52.500. Hasil analisis resiko produksi, resiko harga dan resiko pendapatan berturut- turut nilai koefisien variasinya yaitu 0,13 ; 0,02 ; dan 0,24. Hal tersebut menunjukkan bahwa besarnya risiko yang dihadapai pembudidaya udang vaname di Desa Glagah rendah.
EFEKTIVITAS PROBIOTIK TERHADAP EFISIENSI PAKAN DAN ULAS DARAH IKAN KOMET (Carassius auratus)
Authors: Suseno Dewi Nurmalita , Puspitasari Indah , Jayanti Shara
Published: March 2024

Penelitian ini dilakukan untuk mengetahui potensi efektivitas pemberian probiotik kepada efisiensi pakan dan dalam darah ikan komet sebagai parameter kesehatan ikan. Dosis pakan yang dicampurkan dengan probiotik ialah yaitu (A0=kontrol; A1=50ml/kg; A2=100 ml/kg ml/kg; A3=200 ml/kg; A4=400 ml/kg) dilakukan selama Â± 1,5 bulan masa pemeliharaan. Hasil perhitungan FCR perlakuan A2 hasil analisa varian menggunakan kruskal wallis pada FCR ikan komet menunjukkan adanya perbedaan signifikan (P=0,012) antara ikan yang diberikan dosis probiotik yang berbeda , serta ikan mas komet mampu meningkatkan respon imunitas ikan terhadap antigen yang masuk dalam tubuh ikan,Â  hal ini dibuktikan dengan peningkatan jumlah leukosit dan jumlah aktifitas fagositosis pada preparate ulas darahÂ
Persepsi Kelompok Pembudidaya Ikan (POKDAKAN) Terhadap Kinerja Penyuluh Perikanan Di Dinas Perikanan Kota Samarinda
Authors: Akbar Muhammad Rizki , Sugiharto Eko , Haqiqiansyah Gusti
Published: March 2024

Persepsi merupakan proses seseorang memahami dan mengetahui beberapa hal melalui panca indranya. Latar belakang kehidupan seseorang dapat mempengaruhi timbulnya persepsi pada seseorang. Persepsi yang timbul dari anggota kelompok pembudidaya ikan menjadikan adanya proses pemahaman terhadap penyuluhan yang diberikan baik berupa informasi atau teknologi. Persepsi yang terbentuk dari anggota kelompok pembudidaya ikan dapat menjadi salah satu faktor penghambat atau pendorong dalam pengembangan usaha budidaya sehingga perlu dilakukannya penelitian mengenai persepsi kelompok pembudidaya ikan (POKDAKAN) Karya Joyo Makmur terhadap kinerja penyuluh perikanan dilakukan dari bulan September 2022 hingga Juli 2023. Lokasi penelitian di Kelurahan Lempake, Kecamatan Samarinda Utara, Kota Samarinda. Reesponden berjumlah 10 orang yang terdiri dari seluruh anggota POKDAKAN Karya Joyo Makmur. Tujuan dari penelitian ini untuk mengetahui persepsi POKDAKAN Karya Joyo Makmur terhadap kinerja penyuluh perikanan di Dinas Perikanan Kota Samarinda. Pengambilan data menggunakan kuesioner yang digunakan dalam wawancara. Analisis data yang digunakan dalam penelitian ini adalah Skala Likert. Hasil penelitian menunjukkan bahwa 6 indikator persepsi kinerja berada pada tingkat tinggi atau sangat baik, sedangkan 1 indikator yang berada pada tingkat sedang atau cukup baik. Skor kumulatif dari indikator tersebut adalah 56,01 yang berarti sangat memuaskan.
Studi Perbandingan Histopatologi Udang Vaname yang Terinfeksi Vibrio parahaemolyticus dari Tiga Tambak Berbeda
Authors: Khusnah Asmaul , Satyantini Woro Hastuti , Amin Muhammad
Published: March 2024

Udang vaname merupakan salah satu jenis udang yang memiliki nilai ekonomis tinggi. Hal ini dikarenakan banyaknya permintaan konsumen terhadap udang vaname. Namun budidaya udang vaname tidak mudah, komoditas tersebut mudah terserang penyakit apabila padat tebar terlalu tinggi dan kualitas air yang buruk. Kualitas air yang buruk dapat mengakibatkan imunitas udang vaname menurun dan mengakibatkan mudah terserang penyakit salah satunya Acute Hepatopancreatic Necrosis Disease (AHPND). Penyakit tersebut dilaporkan salah satunya diakibatkan oleh adanya barkteri Vibrio parahaemolyticus yang menginfeksi udang. Tujuan penelitian ini adalah untuk mengetahui kerusakan jaringan udang vaname yang terinfeksi bakteri Vibrio parahaemolyticus di tiga tambak yang berbeda. Metode yang digunakan pada penelitian ini adalah purposive sampling dengan metode observasi. Teknik pengumpulan data dilakukan dengan cara observasi lapang, yakni mengumpulkan data-data primer dan sekunder di lapangan. Data diambil dari tiga lokasi, yaitu Tuban, Sidoarjo dan Pasuruan. Hasil histopatologi dilakukan skoring kerusakan kemudian dianalisis dengan IBM SPSS menggunakan Uji Kruskal Wallis dan dilanjutkan Uji Z. Berdasarkan hasil penelitian menunjukkan bahwa kerusakan jaringan pada insang dan hepatopankreas akibat infeksi dari bakteri V.parahaemolyticus memiliki kerusakan yang cukup parah. Kerusakan yang terjadi pada insang mulai dari fusi lamella dan edema. Sedangkan kerusakan yang terjadi pada hepatopankreas adalah peluruhan sel dan infiltrasi. Maka dapat disimpulkan bahwa ketiga tempat yang terinfeksi V.parahaemolyticus terdapat perbedaan tingkat kerusakan jaringan hepatopankreas dan insang pada udang vaname yang terjadi pada hepatopankreas dan insang banyak hingga sangat banyak. Kerusakan terbanyak terjadi pada sampel udang yang berasal dari Kabupaten Sidoarjo
Religiosity and family resilience who perform Rambu Solo’ Ritual in Toraja
Authors: Pongdatu Laurenzia Putri Salo , Huwae Arthur
Published: March 2024

Rambu Solo’ is one of the customs that the Toraja people still preserve. The implementation of Rambu Solo’ becomes a challenge for some families because this ritual becomes an obligation done as a form of gratitude to people who have died. Besides that, Rambu Solo’s ceremony requires every family to be able to pay off their debt (indan) from the ritual. This problem makes the family depressed, so it is expected that the family can be resilient in daily life. Thus, This study aims to find out the relationship between religiosity and the family resilience of those who carry out Rambu Solo’s ritual in Toraja. The method used is quantitatively correlational. Participants involved as many as 93 Toraja people aged 22-50 years who had or were carrying out Rambu Solo’ ritual using incidental sampling techniques. The measurement scale uses the religiosity scale and the family resilience scale. The results showed a significant positive relationship between religiosity and the family resilience of those who perform Rambu Solo’ ritual in Toraja. This result has implications that families among Toraja who have the debt (Indan) due to carrying out Rambu Solo’ ritual, can survive after getting out of the pressure by paying off their debt (Indan).
Strategi politik golkar pasca orde baru: Studi kasus pemilihan legislatif 2019 di daerah pemilihan Jawa Barat VIII
Authors: Jamil Husnul , Kurniawan Rahmat
Published: March 2024

Setelah Orde Baru, Partai Golkar mengalami penurunan dukungan elektoral secara bertahap sepanjang siklus pemilu berturut-turut. Namun pada pemilu legislatif 2019, Golkar tampil sebagai partai unggulan dalam perolehan suara di daerah pemilihan Jawa Barat VIII. Penelitian ini menggunakan pendekatan penelitian kualitatif dengan menggunakan studi literatur sebagai pengumpulan data untuk memperoleh temuan penelitian. Hasil penelitian menunjukkan bahwa, strategi politik Partai Golkar diawali dengan proses konsolidasi internal partai. Agenda partai secara signifikan menekankan peningkatan pembangunan ekonomi dan penguatan kader dan sayap. Institut Golkar, sebuah organisasi yang didedikasikan untuk pelatihan politik, aktif mencari dan merekrut generasi muda untuk menjadi kader. Pada kampanye pemilu tahun 2019 di daerah pemilihan Jawa Barat VIII, Partai Golkar menerapkan kebijakan tegas nihil toleransi terhadap anggotanya yang terlibat prosedur hukum. Pendekatan ini efektif menjaga reputasi partai dan menumbuhkan kepercayaan masyarakat. Golkar aktif menjalin kerja sama dengan banyak organisasi masyarakat dan pemuda demi menjaga proses demokrasi pada pemilu 2019 di daerah pemilihan Jawa Barat VIII. Golkar di daerah pemilihan Jawa Barat VIII telah melibatkan jasa pakar politik untuk meningkatkan pemahaman geopolitik. Keputusan mengambil alternatif ini dilatarbelakangi oleh terbatasnya sumber daya teknis partai di bidang survei, periklanan, dan pengolahan Big data. Konsultan didatangkan karena partainya menekankan pada manajemen pemilih. Partai Golkar memanfaatkan data besar yang diperoleh dari platform media sosial untuk merumuskan program kampanye yang secara efektif merespons perubahan demografi pemilih, dengan penekanan khusus pada peningkatan dana kampanye politik, pengaruh pemilih muda, dan perluasan akses internet dan media sosial.
Komodifikasi tenaga kerja dalam praktik gotong royong di masyarakat pedesaan
Authors: Enggarianto Alifio Adlin , Masrukin Masrukin , Primadata Ankarlina Pandu
Published: March 2024

Praktik gotong royong yang seharusnya diorientasikan untuk memperkuat kolektivitas dan afektifitas masyarakat telah mengalami perubahan. Perubahan tersebut direfleksikan pada komodifikasi tenaga kerja dalam praktiknya. Berdasarkan hal tersebut, penelitian ini bertujuan untuk menganalisis komodifikasi tenaga kerja dalam praktik gotong royong dan faktor yang melatarbelakanginya. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi kasus, menggunakan purposive sampling untuk pemilihan partisipan dan wawancara mendalam untuk pengumpulan data, sedangkan analisis dilakukan dengan menggunakan model interaktif Miles dan Huberman. Hasil penelitian menunjukkan terjadinya komodifikasi tenaga kerja dalam praktik gotong royong memaknai adanya perubahan hubungan timbal balik di dalam praktiknya. Melalui perspektif George Caspar Homans mengenai pertukaran sosial bahwasannya level analisa hubungan timbal balik dalam sebuah tindakan sosial terletak pada reward (imbalan) yang diharapkan atas cost (pengorbanan) yang dikeluarkan. Sehubungan dengan itu, praktik gotong royong yang semula dijalankan oleh masyarakat untuk mendapatkan imbalan berupa persetujuan sosial mulai mengalami perubahan. Kini praktik gotong royong diukur sebagai komoditas materiil seiring terjadinya ketidaksiapan masyarakat dalam menghadapi tekanan sosial akibat pandemi Covid-19 dan kecemburuan sosial atas ketidakmerataan bantuan sosial di saat pandemi Covid-19. Meskipun pandemi Covid-19 sudah berakhir, komodifikasi tenaga kerja dalam praktik gotong royong masih terjadi karena kecemburuan sosial atas ketidakmerataan bantuan sosial di saat pandemi Covid-19 masih membekas hingga saat ini.
Typological similarities in the lyrical works “The Prisoner to the Butterfly That Flew into His Dungeon” by V. A. Zhukovsky and “The Prisoner of Chillon” by G. G. Byron
Authors: Oksenchuk Vera Nikolaevna
Published: March 2024

The aim of the research is to detect typological similarities in the works of V. A. Zhukovsky and G. G. Byron at the level of the images of the main characters, as well as the spatial-temporal organization of the text, with particular attention to the category of “liberation”. The research material includes lyrical works “The Prisoner to the Butterfly That Flew into His Dungeon” (1813) and “The Prisoner of Chillon” (1816). Comparative studies have already noted the contact links and typological similarities between the creative works of V. A. Zhukovsky and G. G. Byron, but a comparative analysis to identify and study parallels on different levels of the text has not been conducted yet, and this in turn determines the research novelty of the present study. For the first time, an analysis of the texts is presented at the level of characters, themes (prison, prisoner, impossibility of liberation), and spatial-temporal characteristics. The article thoroughly examines the interaction of the two lyrical works at the plot and imagery levels. The basis for examination comprises common elements of plots and motifs, similarities and differences in the images of central characters. The result of the research is that, despite the authorship of the authors belonging to the same literary movement (Romanticism), not only similarities in the realization of such images and situations are observed, but also significant differences. The comparative categories will include: the image of the hero, space and time, the image of freedom, liberation, prison. The identified connections and similarities indicate a literary contact between the authors and literatures, revealing the specifics of contact relationships and typological similarities in the works of V. A. Zhukovsky and G. G. Byron.
Prevención del suicidio. Una perspectiva salubrista. De lo individual a lo colectivo
Authors: Bimbela Pedrola José Luis
Published: March 2024

El suicidio me cuestiona individual y colectivamente. Personal y profesionalmente. Emocional y éticamente. Física y socialmente. Y, desde luego, espiritualmente. Y me alegra muchísimo que desde la salud pública (a la que nada humano le es ajeno) ya se estén poniendo en marcha acciones de todo tipo dirigidas a lograr una prevención eficaz y sostenible en un tema que era tabú hasta hace muy poco tiempo. 

De igual manera que hacer frente, en su momento, a la pandemia del VIH/SIDA con valentía y decisión permitió incorporar mejoras en la salud pública de España que se acabaron consolidando, como el papel activo de pacientes y familiares (tanto en las consultas individuales como en las intervenciones educativas a través de las escuelas de pacientes); si se afronta la cuestión del suicidio con coraje y determinación se podrá alumbrar una nueva sociedad. Mejor y más saludable. Ética, física, emocional, social y espiritualmente. 

De todo ello trataré en ese artículo. Desde la teoría y desde la práctica. Con evidencias científicas y con experiencias vivenciales. Con dichos y con hechos. Con reflexión y con intuición. Con mucho amor y con algo de humor.
Uso e impacto de los programas gubernamentales de apoyo al sector agropecuario de la Comarca Lagunera de Durango, México
Authors: Espinoza-Arellano José De Jesús , García-Zamarripa José Feliciano , Molina-Morejón Víctor Manuel , Gaytán-Mascorro Arturo , Orona-Castillo Ignacio
Published: March 2024

El objetivo de este trabajo fue analizar los programas gubernamentales de apoyo al campo en la Comarca Lagunera de Durango, su origen, cobertura, destino, seguimiento e impactos. La investigación se realizó con un enfoque de estudio de caso. Se diseñó y aplicó un cuestionario con el que se entrevistaron a 89 productores. Se encontró poco seguimiento a los programas derivado del débil sistema de extensionismo agropecuario en la región. Los recursos que el Gobierno Federal ha destinado para el apoyo al campo no se han reflejado en el cumplimiento del objetivo principal del Programa de Fomento a la Agricultura de incrementar la productividad de las unidades de producción.
Evaluación del desarrollo de la comunidad de Yajalón, Chiapas, desde una perspectiva sustentable
Authors: Velázquez Avendaño Jorge Antonio
Published: March 2024

Se evalúa el desarrollo de la comunidad de Yajalón, Chiapas, entre dos posibles orientaciones: hacia un modelo de desarrollo no sustentable y hacia uno sustentable, el cual equilibra el bienestar humano y el beneficio social con el uso de recursos y prácticas productivas comprometidas con la protección ambiental que preserven recursos para las generaciones futuras. La evaluación considera el uso de indicadores y niveles jerárquicos. Para obtener los resultados, se aplicó el Índice General de Sustentabilidad, el cual indica que el IGS de la comunidad se orienta hacia un desarrollo no sustentable en un nivel de inestabilidad. Se concluye que el sistema no tiene la oportunidad de recuperarse y menos aún a la preservación para el futuro.
Vivienda y necesidades estratégicas de género. Un estudio sobre mujeres académicas usando modelos de regresión logística exacta
Authors: Chávez González Martha Eugenia , Saldaña Zepeda Dayna Priscila , Preciado Jiménez Susana Aurelia
Published: March 2024

El objetivo del presente trabajo es evaluar si el arreglo familiar en el que cohabitan las docentes universitarias de una institución pública en México, determina la tenencia y la satisfacción de los espacios de sus viviendas. Para el análisis, se proponen dos modelos de regresión logística exacta que tienen al arreglo familiar como variable predictora para explicar la variabilidad. Los datos fueron recolectados mediante una encuesta en línea. Los resultados encontrados muestran evidencia de que la tenencia de la vivienda a favor de las docentes se efectúa con independencia de la dinámica de relaciones personales en el hogar. En cambio, el arreglo familiar sí explica la percepción de comodidad en los espacios compartidos de la vivienda.
Importancia de la milpa mazahua en el noroeste del Estado de México: perspectiva ante el cambio de uso de suelo
Authors: Marcial Medina Berenice , Marín-Togo María Consuelo , González Pablo Lorena
Published: March 2024

La milpa es un sistema agrícola que engloba prácticas, creencias y conocimientos locales construidos con el paso de los años. El objetivo de este trabajo es reflexionar acerca de la incidencia del cambio de uso de suelo en las diferentes actividades y procesos que se entretejen en la milpa como unidad de estudio, mediante una revisión bibliográfica acerca del tema, en la zona noroeste del Estado de México, México. Se identificaron prácticas agrícolas tradicionales; una amplia diversidad de arvenses con diferentes usos; una diversa gastronomía local asociada y rituales. Finalmente, se reflexiona sobre la manera en que el cambio de uso de suelo afecta los saberes, conocimientos y prácticas relacionadas a este sistema agrícola.
Isolation of novel Actinomyces oris and Aggregatibacter actinomycetemcomitans bacteriophages and study of their biological characteristics in vitro
Authors: Kochetova T. A. , Yuskevich V. V. , Zurabov F. M. , Sadykova G. T. , Medvedev P. V. , Popova V. M.
Published: March 2024

SCIENTIFIC RELEVANCE. The incidence of periodontal infections with antibiotic-resistant strains of Actinomyces oris and Aggregatibacter actinomycetemcomitans capable of forming biofilms in the oral cavity is increasing, and the effectiveness of antimicrobials against biofilms is insufficient. Therefore, the isolation of bacteriophages active against A. oris and Ag. actinomycetemcomitans is an urgent task.

AIM. This study aimed to isolate bacteriophages active against A. oris and Ag. actinomycetemcomitans, study their biological properties, and select optimum culture conditions providing pure lines and high titres of bacteriophages.

MATERIALS AND METHODS. Bacteriophages were isolated from biosamples of saliva, dental plaque, and periodontal pocket contents. The study determined bacteriophage characteristics, including the optimum multiplicity of infection, phage–cell system cultivation time, resistance to various temperatures and pH, and storage stability. Bacteriophage morphology was studied using transmission electron microscopy. Negative colony morphology, lytic activity, host range, and specificity were assessed using spot testing and the Gratia method. Bacterial strains were obtained from the strain collection of the Micromir research and production centre.

RESULTS. The authors isolated and studied 3 novel bacteriophages active against A. oris (vB_AorP_1/G-12, vB_AorP_2/Ch-28, and vB_AorP_3/Bl-35) and 1 bacteriophage active against Ag. actinomycetemcomitans (vB_AacS_1/Dc-1). The A. oris bacteriophages were classified as podoviruses, and the vB_AacS_1/Dc-1 bacteriophage was classified as a siphovirus. The phages formed completely transparent round plaques without a halo, with a diameter ranging from 0.8±0.1 to 4.0±0.2 mm. The optimum parameters established to obtain pure phages with maximum titres included a multiplicity of infection of 0,1–10 and phage–cell system cultivation time of 8–12 hours. The study demonstrated the ability of A. oris bacteriophages to lyse Actinomyces naeslundii strains. Of the 15 A. oris bacteriophage strains studied, vB_AorP_1/G-12, vB_AorP_2/Ch-28, and vB_AorP_3/Bl-35 lysed 10, 8, and 12 bacterial strains, respectively. The vB_AacS_1/Dc-1 phage isolate exhibited lytic activity against both tested strains of Ag. actinomycetemcomitans. The studied phages demonstrated stability under abiotic stress and long-term storage conditions.

CONCLUSIONS. The authors isolated 3 novel bacteriophages active against A. oris and 1 bacteriophage active against Ag. actinomycetemcomitans and studied their biological properties. The isolated bacteriophages are promising as candidates for further research using clinical strains and whole-genome sequencing.
Certification of a pharmacopoeial reference standard for potency testing of recombinant interferon α-2b
Authors: Gaiderova L. A. , Lebedeva Yu. N. , Lobanova T. N. , Lipatova E. K. , Volkova R. A. , Fadeikina O. V.
Published: March 2024

SCIENTIFIC RELEVANCE. Potency testing of recombinant interferons requires a reference standard. The availability of International Standards (ISs) that are commonly used to assess the quality of recombinant interferons is currently limited. Therefore, the quality of interferons should be assessed using pharmacopoeial reference standards (RSs) certified using ISs (if available).

AIM. This study aimed to certify a pharmacopoeial RS for potency testing of recombinant interferon α-2b.

MATERIALS AND METHODS. The potency determination involved comparing the inhibition of the virus-induced cytopathic effect observed in cell culture with the candidate RS and the WHO International Standard for Human rDNA-derived interferon α-2b. The study used A-549 and MDBK cell lines with encephalomyocarditis (EMC) and vesicular stomatitis (VSV) viruses. The authors followed the requirements of the State Pharmacopoeia of the Russian Federation (Cell-Culture Bioassays for Interferon Products, OFS.1.7.2.0002.15). The results were recorded using instrumental and visual methods. The calculations used mathematical statistics. To factor in the influence of intermediate precision, the authors applied Student’s t-test.

RESULTS. The authors developed a certification programme and procedure and certified the pharmacopoeial RS for recombinant human interferon α-2b (rhIFN α-2b) to identify the corresponding medicinal products (by virus neutralisation) and test their potency (by antiviral activity in cell culture). Upon receipt, the candidate RS was verified for compliance with regulatory specifications. According to the test results, the potency of the candidate pharmacopoeial RS was 4.47×10⁸ IU/mL, and the expanded uncertainty was 8.12×10⁷ IU/mL, with a coverage factor of k=2 and a confidence level of 95%. The pharmacopoeial RS for rhIFN α-2b was considered to have the same shelf-life period as the corresponding medicinal products  if stored at a temperature not higher than –40 ºC. When thawed, the pharmacopoeial RS for rhIFN α-2b can be stored at a temperature of 2–8 ºC for up to 1 month.

CONCLUSIONS. Upon certification for potency testing, the pharmacopoeial RS for rhIFN α-2b has been included in the Register of Reference Standards of the Russian Pharmacopoeia as Recombinant Human Interferon α-2b (Potency) FSO.3.2.00455. The introduction of this pharmacopoeial RS will help to conduct the identification and potency testing of all Russian interferon α-2b products at an appropriate scientific and methodological level. As a result, Russian pharmaceutical manufacturers and quality control agencies will no longer depend on imported ISs.
Production and immunological characterisation of recombinant flagellin C of Pseudomonas aeruginosa
Authors: Zherebtsov A. P. , Kaloshin A. A. , Mikhailova N. A.
Published: March 2024

SCIENTIFIC RELEVANCE. Pseudomonas aeruginosa is one of the main causative agents of focal and diffuse suppurative inflammations in immunocompromised individuals. The multiple antimicrobial resistance of Р. aeruginosa has created an urgent need to develop effective preventive vaccines against this bacterium and to enhance their protective properties by selecting adjuvants. A promising strategy is to use flagellin, a P. aeruginosa flagellum component inducing the innate immune system through interaction with toll-like receptor 5 (TLR5) and activating the T-cell immune response, as a component or adjuvant in vaccine development.

AIM. This study aimed to produce recombinant flagellin C (FliC) of P. aeruginosa and investigate its immunogenicity, adjuvanticity, and protective properties.

MATERIALS AND METHODS. The fliC nucleotide sequence was obtained by PCR on template DNA of P. aeruginosa PA-103 and was inserted into the pQE-30 plasmid for subsequent expression in Escherichia coli M15. Recombinant FliC purification involved two stages: isolation of inclusion bodies and their dissolution in buffers containing urea and guanidine hydrochloride. Mice were immunised by two intraperitoneal injections with a two-week interval. The immunisation used purified recombinant FliC at a dose of 50 μg per animal and its combination with the Klebsiella pneumoniae surface antigen in a 1:1 ratio. Serum samples from immunised mice were tested for specific antibodies to recombinant FliC by enzyme-linked immunosorbent assay (ELISA). The protective properties of FliC were assessed by intraperitoneal challenge of mice with cultures of P. aeruginosa PA-103 and K. pneumoniae 204.

RESULTS. The authors obtained the producing strain, generated recombinant FliC, and purified the protein to a 97.6% purity. The analysis of serum samples from immunised mice by ELISA and the protection assessment in challenge experiments showed that the purified recombinant FliC protein had immunogenic properties. Furthermore, the experimental challenge of FliC-immunised mice with P. aeruginosa confirmed that recombinant FliC had protective properties, as evidenced by the protection index of 3.0. Recombinant FliC exhibited adjuvant properties, as demonstrated by the effectiveness index of 6.1 observed in the experimental challenge of mice immunised with the combination of recombinant FliC and the surface antigen of K. pneumoniae.

CONCLUSIONS. The purified recombinant FliC protein of P. aeruginosa demonstrated protective activity in mice challenged with P. aeruginosa and adjuvant properties when combined with the K. pneumoniae surface antigen, increasing the immunogenicity of the latter. The use of recombinant FliC holds promise for the creation of a candidate vaccine against P. aeruginosa infection.
Impact of teacher professional development on student achievement with a focus on Bosnia and Herzegovina: Analyzing TIMSS 2019 results in Western Balkan countries and Croatia
Authors: Bikić Naida , Buzađija Nevzudin , Nuić Ines
Published: March 2024

Students in Bosnia and Herzegovina (B&H) score very low on international assessments (TIMSS & PISA), lower than the countries in the region with which it shares similar background. In this paper the characteristics of teachers’ professional development (TPD) in the region of Western Balkan countries (Albania, B&H, Kosovo, Montenegro, North Macedonia, and Serbia) and Croatia are brought into correlation with average results in mathematics and science on TIMSS 2019. Research questions analyze teachers’ attitudes towards their profession and investigate the impact of professional development (PD) of mathematics and science teachers in the last two years, with a specific focus on the situation in B&H, on students’ achievement in mathematics and science. The findings indicate a lack of TPD as a contributing factor to lower results in B&H. The research suggests that B&H should consider reforms in the education system and enhance teachers’ attitudes towards their profession through intensified PD programs to advance education and learning.
Secondary school teachers’ interest and self-efficacy in implementing STEM education in the science curriculum
Authors: Asilevi Mirjam Ndaimehafo , Havu-Nuutinen Sari , Kang Jingoo
Published: March 2024

This study examines the role of Namibian secondary school science, technology, engineering and mathematics (STEM) teachers’ interest in STEM education and self-efficacy in implementing STEM education in science education curricula. Furthermore, it aimed to distinguish male and female Namibian teachers’ interests and self-efficacy regarding STEM education and investigate how different teaching subjects affect them. To achieve this goal, a survey was completed with (n=200) secondary school teachers, both males and females. Data were analyzed quantitatively using exploratory factor analysis and analyzed covariance. The results show that most teachers were highly interested and confident in implementing STEM subjects into science curricula. While Namibian teachers indicated a high level of interest, they also revealed a high lack of interest in STEM, implying that at least some teachers felt bored and meaningless in implementing STEM education. However, gender plays a significant role in teachers’ negative self-efficacy, with male teachers being less confident than female teachers in implementing STEM education. Moreover, teachers in the present study have high positive and negative self-efficacy levels regarding implementing STEM education. Therefore, these findings highlight the need for a paradigm shift, especially in the Namibian science curricula, to promote STEM subjects and to improve science education. Potential implications from this research also suggest that teachers’ participants benefit significantly from learning within a community by engaging in solutions to real-world problems.
Memory, Trauma, and Liturgies of Exile in Baruch 1:1–3:8
Authors: Wilson Walter T.
Published: March 2024

The book of Baruch describes a set of penitential rituals ostensibly established early in the exilic period to be performed by worshipping assemblies in Babylon and Jerusalem. Prominence is assigned to the ceremonial recitation of a book composed by Baruch in Babylon, which becomes the basis of a letter sent by the exiles to the priests in Jerusalem for use in temple liturgies (1:1–14). As they hear the first part of the book (1:15–3:8), worshippers develop reflexive modes of awareness as they encounter various configurations of time and space, thereby performing exilic subjectivities through which they internalize “prosthetic” memories of loss, subjugation, and disaffection.
Purity, Cult, and Empire
Authors: Rhyder Julia
Published: March 2024

This article analyzes the proclamation of Antiochus III concerning the temple and city of Jerusalem, quoted in Ant. 12.145–46, in light of three sets of evidence: Greek comparative materials from the broader Mediterranean world; biblical and Second Temple writings; and archaeological remains from Hellenistic Jerusalem, especially those that attest to the presence of non-sacrificial animals in the city. The evidence suggests that Ant. 12.145–46 preserves traces of an authentic proclamation, written in the style of a Greek ritual norm and probably with royal backing. We should not conclude from this, however, that the proclamation reflects the reality of how all Jews in Jerusalem conceptualized the purity of the temple and their obligations when butchering and tanning their animals within the city. I rather argue for a more complex interpretive approach that views royal edicts as fueling local debates surrounding temple purity, the sacred economy, and priestly prerogatives in Hellenistic Jerusalem.
Estudo de estabilidade físico-química de preparação extemporânea líquida à base de tretinoína para administração via sonda
Authors: COELHO Letícia Mastrangelo , VEIGA Alan de Almeida , DE SOUZA Lauro Mera , DE SOUZA Gisele Mendes , COSTA Vitor Henrique , CARLOTTO Juliane
Published: March 2024

Objetivo: O estudo visou investigar o teor e a estabilidade físico-química da formulação oral líquida obtida a partir de cápsulas gelatinosas moles de tretinoína (ATRA) no veículo óleo/água, visto a demanda desta formulação para pacientes entubados em tratamento de leucemia promielocítica aguda. Métodos: As análises foram realizadas por Cromatografia Líquida de Alta Eficiência (CLAE) acoplada a detector UV, utilizando coluna C-18. A corrida foi executada com fase móvel composta por água ultrapura com ácido acético glacial 0,5% (v/v) como solvente A e acetonitrila como solvente B, em corrida isocrática (25:75) (A/B), com fluxo de 1 mL/min, temperatura de 30°C e detecção em 355 nm. A injeção da amostra foi de 10 μL e o tempo de corrida foi de 12 min. As formulações orais foram preparadas a partir de ATRA (Vesanoid, FQM) em óleo mineral/água ultrapura (3:7) (v/v), por processo de dissolução e aquecimento a 40ºC, em dosadores orais protegidos da luz e conservadas sob refrigeração (2 - 8°C). As análises foram realizadas nos dias 1, 2, 3, 7, 9 e 14. Resultados: A preparação extemporânea apresentou estabilidade física visual aceitável, com alteração de aspecto pelo enrijecimento da fase aquosa corrigida com aquecimento da formulação em banho-maria a 40°C. O teor de ATRA foi considerado adequado até o D3, conforme a Farmacopeia Brasileira (FB) 6ª edição, apresentando 103,3%, 94,8% e 95,6%, nos dias 1, 2 e 3, respectivamente. A concentração de isotretinoína, produto de degradação, variou de 0,16% a 1,44%, entre os dias 1 e 14, respectivamente. Conclusão: Os resultados sugeriram que a preparação oral líquida apresentou teor satisfatório e estabilidade físico-química por até 48 horas após o preparo, quando conservada protegida da luz e sob refrigeração, conforme preconizado pela RDC 67/2007.
MEDIA TEXTS AND PERSUASION
Authors:   Ivan Franko National University of Lviv, Yatsymirska Mariya , Markevych Bohdan ,   Ivan Franko National University of Lviv
Published: March 2024

Abstract. The article clarifies specific concepts of persuasion in media texts; describes new techniques of media influence based on materials of online publications; shows the role of expressive means of language and emotions in visual communication. In social communication, persuasive logos refer to meaningful words and thoughts conveyed through mass media and logically perceived as a reasonable persuasion to proper actions based on the principles of morality, ethics, and culture; informational and influential accents. In modern science (Philosophy, Psychology, Rhetoric, Linguistics), logos has acquired not only new meanings, but also has become an important concept of rational expression of free ideas, meanings, reflections. From this perspective, new media serve as the most concentrated source of logosphere and eidosphere creation, which should be thoroughly studied and analyzed every day. The research on multimedia texts, genre diversity, new platforms, and online publications has significantly contributed to the Media Studies. Techniques of persuasive communication, methods of argumentation, and verbal tools form a separate area of the research within the field. Unlike manipulation, persuasion is the conscious use of written or spoken language, interactive visualization, and infographics to influence someone’s beliefs, views, or actions; gain someone’s support, approve the suggested ways of behavior, intentions, etc. Means of persuasion in media texts serve as logical information accents aimed at the proper perception of the corresponding meanings. In general, factors of persuasion are to influence the masses and the motivation of their actions, modify views, and form public opinion. In journalism, these are meaningful words, thoughts, principles of high-quality narrative with the use of convincing arguments, facts and, most importantly, positive intentions for the readers. Persuasive media texts exclude manipulation of public opinion, trust and people’s inclination to perceive doctrines imposed on them. Keywords: persuasion, concept, visual information, social communication.
Chitosan Membranes Stabilized with Varying Acyl Lengths Release Cis-2-Decenoic Acid and Bupivacaine at Controlled Rates and Inhibit Pathogenic Biofilm
Authors: Choi Landon Reed , Harrison Zoe , Montgomery Emily C. , Bush Joshua R. , Abuhussein Ezzuddin , Bumgardner Joel D. , Fujiwara Tomoko , Jennings Jessica Amber
Published: March 2024

Background: Adherence of complex bacterial biofilm communities to burned tissue creates a challenge for treatment, with infection causing 51% of burn victim deaths. This study evaluated the release of therapeutics from wound care biomaterials and their antimicrobial activity against pathogens Staphylococcus aureus, Acinetobacter baumannii, and Pseudomonas aeruginosa. Methods: Electrospun chitosan membranes (ESCMs) were fabricated and acylated with chain lengths ranging from 6–10 carbons then loaded with 0.15 mg of anti-biofilm agent, cis-2-decenoic acid (C2DA), and 0.5 mg of local anesthetic, bupivacaine. Results: Combinations of therapeutics released from modified ESCMs at a cumulative amount of 45–70% of bupivacaine and less than 20% of C2DA. Results from bacterial studies suggest that this combination reduced biofilm 10-fold for S. aureus, 2-fold for Acinetobacter baumannii, and 2–3-fold for Pseudomonas aeruginosa by 24 hours. Additionally, dual loaded groups reduced planktonic Staphylococcus aureus ~4-fold by 24 hours as well as Acinetobacter baumannii ~3-fold by 48 hours. Conclusions: The combination of therapeutics used has a significant role in biofilm prevention for selected strains via direct contact or diffusion in aqueous solutions.