bluuebunny/crossref_metadata_2025 huggingface dataset:
Instituições de formação de professores como comunidades de escrita: estudo com base nos títulos dos relatórios de mestrado
Authors: Filipe Barbeiro Luís , António Brandão Carvalho José , Barbeiro Célia
Published: June 2022

As escolhas e decisões na escrita académica incluem o próprio título. As escolhas podem envolver estruturas linguísticas, marcas de pontuação, estratégias comunicativas, aspetos gráficos. Elas refletem-se na adequação aos objetivos sociocomunicativos do género e na projeção alcançada na comunidade académica. O presente estudo incide sobre os títulos dos relatórios de mestrado em quatro instituições de ensino superior portuguesas de formação de educadores de infância e professores. O objetivo do estudo é observar se as características dos títulos diferenciam as instituições, apontando para a existência de comunidades próprias de implementação destes mestrados e de escrita académica. Para a realização do estudo, reuniu-se um corpus de 800 relatórios de mestrado e efetuou-se a análise comparativa dos títulos quanto ao número de elementos, estrutura, estratégias comunicativas, presença no título das dimensões de prática profissional e de investigação e outros indicadores facultados pela Linguística de Corpus, como frequência de palavras e palavras-chave. Os resultados revelam diferenças entre as instituições quanto à predominância das escolhas em relação aos títulos, designadamente quanto ao número de elementos, estruturas sintático-semânticas, estratégias, palavras-chave e saliência dada às dimensões pedagógica e investigativa. Estes resultados indicam que as instituições se constituem como comunidades locais, nas quais predominam determinadas escolhas. As diferenças remetem para o seu funcionamento enquanto comunidade científica de formação, comunidade discursiva e também comunidade de escrita académica. Nesta última dimensão, o desafio é que a comunidade de cada instituição, sem anular a sua identidade, potencie as funções que quer atribuir aos títulos.
Cambios fisicoquímicos y antioxidantes de zapote negro (Diospyros digyna, Ebenaceae) durante el desarrollo de frutos en el árbol
Authors: Merino-Sánchez Liliana , Romero-Luna Haydee Eliza , García-Barradas Oscar , Mendoza-López María Remedios , Jiménez Fernández Maribel
Published: June 2022

Antecedentes y Objetivos: El fruto de Diospyros digyna, conocido como zapote negro, es un fruto exótico, consumido y comercializado en el sur de México. Ha sido poco estudiado y se desconocen los cambios en los perfiles de sus propiedades fisicoquímicas y antioxidantes durante su etapa de desarrollo en el árbol. Por lo tanto, los objetivos de este estudio fueron 1) evaluar las propiedades fisicoquímicas y la actividad antioxidante durante el desarrollo y maduración de frutos de D. digyna, con el fin de conocer los cambios del fruto, y 2) establecer el momento adecuado de cosecha de este fruto climatérico. Métodos: Se evaluaron las propiedades físicas del fruto D. digyna, tales como, firmeza, color, velocidad de respiración del fruto completo, así como la composición proximal, el índice de madurez y compuestos bioactivos incluyendo actividad antioxidante de la pulpa del fruto, esto cada dos semanas durante 14 semanas de desarrollo del fruto en el árbol.Resultados clave: Durante el período de análisis de 14 semanas, el peso y las dimensiones del fruto de D. digyna aumentaron en aproximadamente 90%. El contenido de vitamina C incrementó de 60 a 369 mg/100 g de fruta fresca. Sin embargo, la concentración de carotenoides totales, taninos, polifenoles, acidez y tasa de respiración disminuyeron. La actividad antioxidante determinada por el porcentaje de captación de radicales DPPH (2, 2-difenil-1-picrilhidrazilo) fue de 30%, junto con un alto poder reductor (2.4 D.O.) al final del estudio. La resistencia a la fractura de la cáscara y la pulpa de la fruta fue de 1.4 N y 5.35 N, respectivamente. Conclusiones: Este estudio realiza un seguimiento de los cambios físicos, en la respiración, composición y actividad antioxidante ocurridos durante el desarrollo del fruto D. digyna en el árbol, demostrando que la semana 10 es el mejor momento de cosecha, ya que no hay cambios importantes a partir de ese momento. Así mismo, se confirma que el zapote negro puede ser una fuente importante de vitamina C.
Biología reproductiva y distribución potencial de Ficus pringlei (Moraceae), una especie microendémica del Nuevo Mundo
Authors: Rojas-Cortés Ángela P. , Cuervo-Robayo Ángela P. , Cornejo-Tenorio Guadalupe , Ibarra-Manríquez Guillermo
Published: June 2022

Antecedentes y Objetivos: Uno de los géneros de árboles más diversos y ecológicamente importantes de los trópicos es Ficus. La caracterización de las fases de desarrollo y cambios morfológicos de su sicono es fundamental para facilitar los estudios de polinización y dispersión, pero estos aspectos solo se han caracterizado en pocas especies en América. Ficus pringlei es endémico de México y no se dispone de información detallada sobre su distribución potencial y aspectos reproductivos. Este estudio tuvo como objetivo describir las fases del desarrollo del sicono de F. pringlei, determinar su tipo de polinización, y detectar áreas con ambientes potencialmente adecuados para localizarlo.
Métodos: Se recolectaron siconos para describir las diferentes fases de su desarrollo. Los siconos y sus avispas polinizadoras se fijaron en alcohol para ser procesadas y descritas mediante microscopía electrónica de barrido. Se usaron modelos de nicho ecológico para predecir áreas con ambientes adecuados para localizar a F. pringlei.
Resultados clave: El sicono cambió de tamaño, color, consistencia y forma del ostiolo durante sus fases de desarrollo; particularmente en las etapas más críticas de su interacción con polinizadores o dispersores. Se registró un desarrollo asincrónico, tanto a nivel individual, como poblacional, de los siconos. Ficus pringlei presenta una polinización activa. El área potencialmente adecuada de distribución se concentró principalmente en los bosques tropicales secos de los estados de Jalisco y Michoacán. La variable más importante para explicar el modelo de distribución de F. pringlei fue la estacionalidad de la temperatura, con valores mayores en las zonas al norte de la Faja Volcánica Transmexicana.
Conclusiones: Las diferentes fases de desarrollo de esta especie son consistentes con las descritas previamente para otras especies monoicas. Ficus pringlei solo se distribuye en el occidente de México, principalmente en bosques tropicales secos y se encuentra minoritariamente en Áreas Protegidas. Por lo tanto, es importante establecer estrategias que aseguren su conservación.
FORMATION OF CYTOKINE-HORMONAL INTERACTIONS AT BOYS WITH DIFFUSE NONTOXIC GOITER WITH PHYSIOLOGICAL AND PATHOLOGICAL PUBERTY
Authors: Plekhova O. I. , Shlyakhova N. V. , Turchina S. I.
Published: June 2022

Cytokine-hormonal interrelations at 291 boys aged 14–17 adjusted to level of puberty and the thyroid gland condition were analyzed. It was shown that the formation of cytokine-hormonal relationships depends on of the both on presences of thyroid pathologies and on degree of puberty. The role of cytokines increased at boys both with thyroid pathology and the sex delay development. Existence of close connections between thyroid, sex hormones, insulin-like growth factor, sex hormonebinding globulin, melatonin and cytokines (IL-1β, TNF-α, IL-6, IL-10) also was established. The character and the structure of interactions reflected the differences in formation of mechanisms of the sex delay development against the thyroid gland pathology.
INFLUENCE OF BLOOD PRESSURE, BODY WEIGHT AND GLYCEMIC LEVEL ON THE DEVELOPMENT OF DIABETIC POLYNEUROPATHY
Authors: Orlyk O. S. , Mankovskyi B. M.
Published: June 2022

It studied influence of different factors on diabetes neuropathy of different severity are represent in the article. The degree of manifestation of neurological symptoms was avaluated by the score NSS (Neurological Symptoms Score). Patients with index up to 5 points by NSS score had a mild grade of diabetes neuropathy; the group with medium grade of diabetes neuropathy indicated from 5 to 10 points; last group with most severe grade of diabetes neuropathy included patients with index more then 10 point by the score NSS. It studied the influence on severity of diabetes polyneuropathy such factors as: body mass index, glycemic compensation and blood pressure in patients with diabetes mellitus. In conclusion we must say, that factors which predispose to diabetic polyneuropathy are: decompensation of diabetes, marked obesity and arterial hypertension
Laparoscopic retropubic extraurethral adenomectomy
Authors: Eremenko S. N. , Eremenko A. N. , Mykhaylichenko V. Yu. , Dolgopolov V. P. , Chernega V. S. , Khalilova A. S.-A.
Published: June 2022

Introduction. Existing methods of surgical treatment of benign prostatic hyperplasia are accompanied by the frequent development of postoperative complications, such as urinary incontinence, retrograde ejaculation, and urethral strictures. The method of preserving the prostatic urethra has been developed for a long time. At present, it is possible to use the operation technique and perform laparoscopic urethral-sparing adenomectomy.Objective. To assess the possibility of performing extraurethral adenomectomy with prostatic urethral preservation using the laparoscopic approach, its advantages and disadvantages.Materials and methods. Based on St. Luke’s Simferopol сlinical Multidisciplinary Medical Center, 35 successful laparoscopic operations were performed to remove benign prostate hyperplasia with the prostatic urethra preservation. The features of the operation are laparoscopic access, a transverse section of the capsule, alternate isolation of adenomatous nodes while preserving the prostatic urethra on the catheter without replacing it during the operation, suturing the capsule with a decrease in space from the removed adenomatous nodes. Urethral preservation provided accelerated epithelialization of the defect, in the absence of the formation of a “prevesical” space.Results. After the operation, it is possible to turn off the urinary bladder irrigation system earlier (up to 4 – 6 hours after the operation) and early removal of the catheter after surgery (2 – 3 days). The hospital stay averaged 5.7 days. Urination was restored immediately after catheter removal in 92% of the patients. There were no elements of dysuria, particularly urinary incontinence. Prostate volume measured throughout transrectal ultrasound after operation was 20 – 24 cm³.Conclusion. The technique of retropubic extraurethral adenomectomy with prostatic urethral preservation can be performed in laparoscopic technique. The advantages are early activation of the patient and discharge from the hospital, early removal of the catheter with restoration of independent urination, absence of dysuria, urinary incontinence, and postoperative complications. The results of our study demonstrate the effectiveness of the laparoscopic extraurethral adenomectomy technique, the further development of this technique, and the possibility of its application in practice.
Identifying Potential Gamification Elements for A New Chatbot for Families With Neurodevelopmental Disorders: User-Centered Design Approach
Authors: Bui Truong An , Pohl Megan , Rosenfelt Cory , Ogourtsova Tatiana , Yousef Mahdieh , Whitlock Kerri , Majnemer Annette , Nicholas David , Demmans Epp Carrie , Zaiane Osmar , Bolduc François V
Published: June 2022

Background

Chatbots have been increasingly considered for applications in the health care field. However, it remains unclear how a chatbot can assist users with complex health needs, such as parents of children with neurodevelopmental disorders (NDDs) who need ongoing support. Often, this population must deal with complex and overwhelming health information, which can make parents less likely to use a software that may be very helpful. An approach to enhance user engagement is incorporating game elements in nongame contexts, known as gamification. Gamification needs to be tailored to users; however, there has been no previous assessment of gamification use in chatbots for NDDs.

Objective

We sought to examine how gamification elements are perceived and whether their implementation in chatbots will be well received among parents of children with NDDs. We have discussed some elements in detail as the initial step of the project.

Methods

We performed a narrative literature review of gamification elements, specifically those used in health and education. Among the elements identified in the literature, our health and social science experts in NDDs prioritized five elements for in-depth discussion: goal setting, customization, rewards, social networking, and unlockable content. We used a qualitative approach, which included focus groups and interviews with parents of children with NDDs (N=21), to assess the acceptability of the potential implementation of these elements in an NDD-focused chatbot. Parents were asked about their opinions on the 5 elements and to rate them. Video and audio recordings were transcribed and summarized for emerging themes, using deductive and inductive thematic approaches.

Results

From the responses obtained from 21 participants, we identified three main themes: parents of children with NDDs were familiar with and had positive experiences with gamification; a specific element (goal setting) was important to all parents, whereas others (customization, rewards, and unlockable content) received mixed opinions; and the social networking element received positive feedback, but concerns about information accuracy were raised.

Conclusions

We showed for the first time that parents of children with NDDs support gamification use in a chatbot for NDDs. Our study illustrates the need for a user-centered design in the medical domain and provides a foundation for researchers interested in developing chatbots for populations that are medically vulnerable. Future studies exploring wide range of gamification elements with large number of potential users are needed to understand the impact of gamification elements in enhancing knowledge mobilization.
A Remote Digital Monitoring Platform to Assess Cognitive and Motor Symptoms in Huntington Disease: Cross-sectional Validation Study (Preprint)
Authors: Lipsmeier Florian , Simillion Cedric , Bamdadian Atieh , Tortelli Rosanna , Byrne Lauren M , Zhang Yan-Ping , Wolf Detlef , Smith Anne V , Czech Christian , Gossens Christian , Weydt Patrick , Schobel Scott A , Rodrigues Filipe B , Wild Edward J , Lindemann Michael
Published: June 2022

BACKGROUND

Remote monitoring of Huntington disease (HD) signs and symptoms using digital technologies may enhance early clinical diagnosis and tracking of disease progression, guide treatment decisions, and monitor response to disease-modifying agents. Several recent studies in neurodegenerative diseases have demonstrated the feasibility of digital symptom monitoring.

OBJECTIVE

The aim of this study was to evaluate a novel smartwatch- and smartphone-based digital monitoring platform to remotely monitor signs and symptoms of HD.

METHODS

This analysis aimed to determine the feasibility and reliability of the Roche HD Digital Monitoring Platform over a 4-week period and cross-sectional validity over a 2-week interval. Key criteria assessed were feasibility, evaluated by adherence and quality control failure rates; test-retest reliability; known-groups validity; and convergent validity of sensor-based measures with existing clinical measures. Data from 3 studies were used: the predrug screening phase of an open-label extension study evaluating tominersen (NCT03342053) and 2 untreated cohorts—the HD Natural History Study (NCT03664804) and the Digital-HD study. Across these studies, controls (n=20) and individuals with premanifest (n=20) or manifest (n=179) HD completed 6 motor and 2 cognitive tests at home and in the clinic.

RESULTS

Participants in the open-label extension study, the HD Natural History Study, and the Digital-HD study completed 89.95% (1164/1294), 72.01% (2025/2812), and 68.98% (1454/2108) of the active tests, respectively. All sensor-based features showed good to excellent test-retest reliability (intraclass correlation coefficient 0.89-0.98) and generally low quality control failure rates. Good overall convergent validity of sensor-derived features to Unified HD Rating Scale outcomes and good overall known-groups validity among controls, premanifest, and manifest participants were observed. Among participants with manifest HD, the digital cognitive tests demonstrated the strongest correlations with analogous in-clinic tests (Pearson correlation coefficient 0.79-0.90).

CONCLUSIONS

These results show the potential of the HD Digital Monitoring Platform to provide reliable, valid, continuous remote monitoring of HD symptoms, facilitating the evaluation of novel treatments and enhanced clinical monitoring and care for individuals with HD.
User Perceptions of eHealth and mHealth Services Promoting Physical Activity and Healthy Diets: Systematic Review (Preprint)
Authors: Bergevi Julia , Andermo Susanne , Woldamanuel Yohannes , Johansson Unn-Britt , Hagströmer Maria , Rossen Jenny
Published: June 2022

BACKGROUND

Physical activity and a diet that follows general recommendations can help to prevent noncommunicable diseases. However, most adults do not meet current recommended guidelines, and support for behavior change needs to be strengthened. There is growing evidence that shows the benefits of eHealth and mobile health (mHealth) services in promoting healthy habits; however, their long-term effectiveness is uncertain because of nonadherence.

OBJECTIVE

We aimed to explore users’ perceptions of acceptability, engagement, and usability of eHealth and mHealth services that promote physical activity, healthy diets, or both in the primary or secondary prevention of noncommunicable diseases.

METHODS

We conducted a systematic review with a narrative synthesis. We performed the literature search in PubMed, PsycINFO, and CINAHL electronic databases in February 2021 and July 2021. The search was limited to papers published in English between 2016 and 2021. Papers on qualitative and mixed method studies that encompassed eHealth and mHealth services for adults with a focus on physical activity, healthy diet, or both in the primary or secondary prevention of noncommunicable diseases were included. Three authors screened the studies independently, and 2 of the authors separately performed thematic analysis of qualitative data.

RESULTS

With an initial finding of 6308 articles and the removal of 427 duplicates, 23 articles were deemed eligible for inclusion in the review. Based on users’ preferences, an overarching theme—eHealth and mHealth services provide value but need to be tailored to individual needs—and 5 subthemes—interactive and integrated; varying and multifunctional; easy, pedagogic, and attractive; individualized and customizable; and reliable—emerged.

CONCLUSIONS

New evidence on the optimization of digital services that promote physical activity and healthy diets has been synthesized. The findings represent users’ perceptions of acceptability, engagement, and usability of eHealth and mHealth services and show that services should be personalized, dynamic, easily manageable, and reliable. These findings can help improve adherence to digital health-promoting services.
Virtual Specialist Care During the COVID-19 Pandemic: Multimethod Patient Experience Study (Preprint)
Authors: Dainty Katie N , Seaton M Bianca , Estacio Antonio , Hicks Lisa K , Jamieson Trevor , Ward Sarah , Yu Catherine H , Mosko Jeffrey D , Kassardjian Charles D
Published: June 2022

BACKGROUND

Transitioning nonemergency, ambulatory medical care to virtual visits in light of the COVID-19 global pandemic has been a massive shift in philosophy and practice that naturally came with a steep learning curve for patients, physicians, and clinic administrators.

OBJECTIVE

We undertook a multimethod study to understand the key factors associated with successful and less successful experiences of virtual specialist care, particularly as they relate to the patient experience of care.

METHODS

This study was designed as a multimethod patient experience study using survey methods, descriptive qualitative interview methodology, and administrative virtual care data collected by the hospital decision support team. Six specialty departments participated in the study (endoscopy, orthopedics, neurology, hematology, rheumatology, and gastroenterology). All patients who could speak and read English and attended a virtual specialist appointment in a participating clinic at St. Michael’s Hospital (Toronto, Ontario, Canada) between October 1, 2020, and January 30, 2021, were eligible to participate.

RESULTS

During the study period, 51,702 virtual specialist visits were conducted in the departments that participated in the study. Of those, 96% were conducted by telephone and 4% by video. In both the survey and interview data, there was an overall consensus that virtual care is a satisfying alternative to in-person care, with benefits such as reduced travel, cost, time, and SARS-CoV-2 exposure, and increased convenience. Our analysis further revealed that the specific reason for the visit and the nature and status of the medical condition are important considerations in terms of guidance on where virtual care is most effective. Technology issues were not reported as a major challenge in our data, given that the majority of “virtual” visits reported by our participants were conducted by telephone, which is an important distinction. Despite the positive value of virtual care discussed by the majority of interview participants, 50% of the survey respondents still indicated they would prefer to see their physician in person.

CONCLUSIONS

Patient experience data collected in this study indicate a high level of satisfaction with virtual specialty care, but also signal that there are nuances to be considered to ensure it is an appropriate and sustainable part of the standard of care.
An International Core Capability Framework for Physiotherapists to Deliver Quality Care via Videoconferencing: A Delphi Study (Preprint)
Authors: Davies Luke , Hinman Rana S , Russell Trevor , Lawford Belinda , Bennell Kim ,   International Videoconferencing Steering Group
Published: June 2022

BACKGROUND

The provision of physiotherapy care via telehealth is becoming increasingly common and, in some circumstances, is a necessity, as observed during the COVID-19 pandemic. Therefore, it is important to understand what are the core capabilities that physiotherapists need in order to deliver quality care via videoconferencing.

OBJECTIVE

The objective of our study was to develop a discipline-specific core capability framework for physiotherapists to deliver quality care via videoconferencing.

METHODS

An international Delphi panel comprising a steering group and experts in the field, including physiotherapy researchers, physiotherapy clinicians, representatives of physiotherapy organizations, and consumers, was established by drawing on the research team’s academic, research, and clinical networks as well as contacting international physiotherapy organizations. The draft framework was developed by the research team and steering group, based on relevant documents identified within the literature. The panel considered a draft framework of 73 specific capabilities mapped across 8 domains. Over 3 rounds, panelists rated their agreement (Likert or numerical rating scales) on whether each capability was essential (core) for physiotherapists to deliver quality care via videoconferencing. The capabilities that achieved consensus, defined as 75% of the panel ratings being ≥7 out of 10 in round 3, were retained.

RESULTS

A total of 130 panelists from 32 countries participated in round 1, with retention rates of 65% and 60% in rounds 2 and 3, respectively. The final framework comprised 60 capabilities across the following seven domains: compliance (capabilities: n=7), patient privacy and confidentiality (capabilities: n=4), patient safety (capabilities: n=7), technology skills (capabilities: n=7), telehealth delivery (capabilities: n=16), assessment and diagnosis (capabilities: n=7), and care planning and management (capabilities: n=12).

CONCLUSIONS

This framework outlines the specific core capabilities that are required of physiotherapists to provide quality care via videoconferencing. The core capability framework provides guidance for physiotherapists to deliver care via videoconferencing and will help inform the future development of physiotherapy curricula and professional development initiatives in the delivery of telehealth.
Social Media Listening and Digital Profiling Study of People With Headache and Migraine: Retrospective Infodemiology Study (Preprint)
Authors: Goadsby Peter , Ruiz de la Torre Elena , Constantin Luminita , Amand Caroline
Published: June 2022

BACKGROUND

There is an unmet need for a better understanding and management of headache, particularly migraine, beyond specialist centers, which may be facilitated using digital technology.

OBJECTIVE

The objective of this study was to identify where, when, and how people with headache and migraine describe their symptoms and the nonpharmaceutical and medicinal treatments used as indicated on social media.

METHODS

Social media sources, including Twitter, web-based forums, blogs, YouTube, and review sites, were searched using a predefined search string related to headache and migraine. The real-time data from social media posts were collected retrospectively for a 1-year period from January 1, 2018, to December 31, 2018 (Japan), or a 2-year period from January 1, 2017, to December 31, 2018 (Germany and France). The data were analyzed after collection, using content analysis and audience profiling.

RESULTS

A total of 3,509,828 social media posts related to headache and migraine were obtained from Japan in 1 year and 146,257 and 306,787 posts from Germany and France, respectively, in 2 years. Among social media sites, Twitter was the most used platform across these countries. Japanese sufferers used specific terminology, such as “tension headaches” or “cluster headaches” (36%), whereas French sufferers even mentioned specific migraine types, such as ocular (7%) and aura (2%). The most detailed posts on headache or migraine were from Germany. The French sufferers explicitly mentioned “headache or migraine attacks” in the “evening (41%) or morning (38%),” whereas Japanese mentioned “morning (48%) or night (27%)” and German sufferers mentioned “evening (22%) or night (41%).” The use of “generic terms” such as medicine, tablet, and pill were prevalent. The most discussed drugs were ibuprofen and naproxen combination (43%) in Japan; ibuprofen (29%) in Germany; and acetylsalicylic acid, paracetamol, and caffeine combination (75%) in France. The top 3 nonpharmaceutical treatments are hydration, caffeinated beverages, and relaxation methods. Of the sufferers, 44% were between 18 and 24 years of age.

CONCLUSIONS

In this digital era, social media listening studies present an opportunity to provide unguided, self-reported, sufferers’ perceptions in the real world. The generation of social media evidence requires appropriate methodology to translate data into scientific information and relevant medical insights. This social media listening study showed country-specific differences in headache and migraine symptoms experienced and in the times of the day and treatments used. Furthermore, this study highlighted the prevalence of social media usage by younger sufferers compared to that by older sufferers.

CLINICALTRIAL
The acceptability, safety, and effects of a smartphone application for university students who self-harm: an open study (Preprint)
Authors: Cliffe Bethany , Moore Emma , Whittle Kathryn , Stallard Paul
Published: June 2022

BACKGROUND

Many university students self-harm but very few seek professional support for it. Smartphone apps have been identified as acceptable sources of support for students who self-harm, but they are yet to be explored in this population.

OBJECTIVE

This study sought to explore the acceptability, safety and effects of a specific app (BlueIce) with university students.

METHODS

This was a small, exploratory, mixed methods study with university students attending university wellbeing services who were struggling with self-harm. Self-harm thoughts and behaviours, coping self-efficacy, and symptoms of anxiety, depression and borderline personality disorder were measured before and after students used the app alongside treatment as usual for 6 weeks. Follow up interviews were also used to explore how students perceived BlueIce in more in depth.

RESULTS

There were improvements in scores on measures of mental health, and participants found BlueIce to be acceptable, safe and helpful. They reported feeling more able to cope with difficult feelings following using the app, and better understood what triggered self-harm for them. They also discussed how it had benefitted their general wellbeing, and felt it could be widely helpful for students struggling with various difficulties further to self-harm.

CONCLUSIONS

Overall, BlueIce was an acceptable, safe and helpful source of support for university students struggling with self-harm thoughts and/or behaviours in this study.

CLINICALTRIAL

N/A
Identity Crisis As A Threat Among Indonesian Young Generations
Authors: Manurung Elisha Samantha Dewi , Salsabila Faukha Ilmania , Wirawan Putu Tanisya Putri , Anggraini Nadila Dwi , Pandin Moses Glorino Rumambo
Published: June 2022

In living life as a part of a nation and state, people sometimes feel confused about what is more important between the country and the state, and they sometimes even underestimate the two. The state is an organization of power from the fellowship of human life, while the nation refers to the harmony of human life. A country must have its own national identity that differs from other countries since the national identity of a nation shows its personality. This study aims to observe the condition of national identity among the young generation and attempts to overcome the threat of a national identity crisis. The method used in this study is descriptive analysis with data collection techniques by conducting surveys and interviews. The population in this study consist of private high school and university students. In this study, the sample used was 160 people aged 15-20 years. The results indicated that the young generation is at a critical stage of national identity. It was caused by their inabilities to wisely use technology and a lack of sense of nationalism as well as love for their homeland. This study found many, lacks as it is seen in the students who still used their respective regional languages because they were vulnerable to any trigger according to the perspectives, principles, and goals of each student. Furthermore, based on research results, teenagers tend to be more fond of foreign cultures and consider Indonesian cultural heritage outdated. For this reason, it is necessary to instill a sense of pride and love for the homeland among young people so that the culture remains sustainable. The researchers suggest the Indonesian people, especially the young generation to have more concern about the national identity of the Indonesian nation since it is essential to increase the horizon of knowledge, and it is also hoped that the young generation can apply an understanding on national identity and be able to implement the points of Pancasila in life nation, society, and state.
Intrapersonal Factors Relationship in Adolescent Pregnancy
Authors: Damayanti Nyoman Anita , Sulistyorini Yuly , Purnomo Windhu , Hargono Rachmat , Hariastuti Iswari , Herowati Diyah , Mardiyono Mardiyono , Aziz Udin Kurniawan , Religia Wandera Ahmad
Published: June 2022

IDHS (2017) shows that there is most unwanted pregnancy among young women in the age group of 15-19 years (16.4%). The unwanted pregnancy can be caused by several factors. Malang Regency had a 15-19 year ASFR of 47.71 in 2018, which was higher than the national target. For this reason, it is significant to conduct research for addressing adolescent pregnancy and to analyze the relationship between interpersonal factors (level of education, employment status, and dating experience) and adolescent pregnancy. The researchers used a case-control design in 50 villages in 15 subdistricts of Malang District. The respondents consisted of 114 adolescent women (20-25 years old) divided into case groups (who had been pregnant at age 19 years) and the control group (who did not get pregnant at age 19 years). They were then interviewed using questionnaires, and the data were analyzed using statistical tests. The results showed that there is a significant relationship between the level of education and adolescent pregnancy (p = 0.000 < α, C = 0.618). On the other hand, there is no relationship between employment status (p = 0.424), dating experience (p = 0.438), and adolescent pregnancy. Therefore, adolescents do not only need to be encouraged to pursue higher education to improve adolescent self-quality but they also need to prevent themselves from pregnancy.
Jarak Sosial antara Keturunan Cina dan Pribumi dalam Proses Pembauran Di Kecamatan Rengasdengklok Kabupaten Karawang
Authors: Yulia Lia , Akhmad Nulhaqim Soni
Published: June 2022

Penelitian ini membahas jarak sosial yang terjadi antara etnik keturuna Cina dan Pribumi sehingga terjadi ketidakharmonisan kehidupan sosial dalam upaya proses pembauran di Kecamatan Rengasdengklok Kabupaten Karawang. Penelitian ini menggunakan pendekatan kualitatif yaitu metode deskriptif analitis untuk mencari faktor apa yang menimbulkan terjadinya jarak sosial antar etnik, terutama antara keturunan Cina dengan masyarakat pribumi dan bagaimana persepsi masyarakat keturunan Cina dan masyarakat Pribumi terhadap perwujudan pembauran di Kecamatan Rengasdengklok. Hasil penelitian menunjukkan bahwa ada tiga faktor penentu terjadinya jarak sosial yang mempengaruhi proses pembauran antar etnik keturunan Cina dan Pribumi, yaitu: stereotip, prasangka sosial, dan perilaku diskriminasi. Sedangkan persepsi masyarakat keturunan Cina dan Pribumi terhadap perwujudan pembauran di Kecamatan Rengasdengklok adalah bahwa pembauran atau asimilasi merupakan kesadaran yang datang dari hati nurani masyarakat itu sendiri yang mau menerima perbedaan budaya antar etnik, terutama di wilayah Kecamatan Rengasdengklok.
Petani Muda dalam Kewirausahaan Sosial Kubis di Desa Cisanta
Authors: Kurniasandi Didi , Hartono Rudi , Maryani Ait
Published: June 2022

Saat ini, jumlah rumah tangga petani muda di Indonesia sangat sedikit, sedangkan untuk pertanian keberlanjutan sangat diperlukan keterlibatan petani muda. Teknologi GAP belum banyak diterapkan padahal sangat penting untuk menjamin produk panen yang aman dikonsumsi. Telah dilakukan penelitian untuk menganalisis secara deskriptif kapasitas kewirausahaan dan penerapan GAP serta faktor-faktor yang berhubungan dengan strategi peningkatannya. Penelitian dilaksanakan di Desa Cisantana, Kecamatan Cigugur, Kabupaten Kuningan, Jawa Barat terhadap 31 petani muda sebagai responden. Variabel yang diteliti adalah karakteristik responden, dukungan penyuluhan, dan minat petani muda menggunakan metode observasi, pengisian kuisioner, serta wawancara. Data dianalisis deskriptif, korelasi rank spearman, dan non-parametrik kendall’s W. Hasilnya penelitian menunjukan bahwa kapasitas kewirausahaan petani muda dan penerapan budidaya GAP kubis yang termasuk dalam kategori sedang. Dukungan penyuluhan secara signifikan berhubungan kuat dengan kapasitas kewirausahaan petani muda, sedangkan karakteristik pengalaman pelatihan dan karakteristik luas lahan secara signifikan berhubungan kuat dengan penerapan GAP. Untuk strategi peningkatan disajikan dalam rencana kegiatan penyuluhan materi administrasi GAP dan keterampilan sosial. Pemilihan media dan metode penyuluhan yang digunakan disesuaikan dengan kondisi di lapangan.
Urine Output Monitoring for the Diagnosis of Early-Onset Acute Kidney Injury in Very Preterm Infants
Authors: De Mul Aurélie , Parvex Paloma , Héneau Alice , Biran Valérie , Poncet Antoine , Baud Olivier , Saint-Faust Marie , Wilhelm-Bals Alexandra
Published: June 2022

Background and objectives

The current threshold used for oliguria in the definition of neonatal AKI has been empirically defined as 1 ml/kg per hour. Urine output criteria are generally poorly documented, resulting in uncertainty in the most accurate threshold to identify AKI in very preterm infants with known tubular immaturity.

Design, setting, participants, & measurements

We conducted a bicentric study including 473 very preterm infants (240/7–296/7 weeks of gestation) born between January 2014 and December 2018 with urine output measurements every 3 hours during the first 7 days of life and two serum creatinine measurements during the first 10 days of life. AKI was defined using the neonatal Kidney Disease Improving Global Outcomes (KDIGO) definition. We tested whether higher urine output thresholds (1.5 or 2 ml/kg per hour) in modified AKI definitions may better discriminate neonatal mortality compared with the current definition.

Results

Early-onset AKI was developed by 101 of 473 (21%) very preterm infants. AKI was diagnosed on the basis of urine output criteria alone (no rise in creatinine) for 27 of 101 (27%) participants. Early-onset AKI was associated with higher risk of death before discharge (adjusted odds ratio, 3.9; 95% confidence interval, 1.9 to 7.8), and the AKI neonatal KDIGO score showed good discriminative performance for neonatal mortality, with an area under the receiver operating characteristic (ROC) curve of 0.68 (95% confidence interval, 0.61 to 0.75). Modified AKI definitions that included higher urine output thresholds showed significantly improved discriminative performance, with areas under the ROC curve of 0.73 (95% confidence interval, 0.66 to 0.80) for the 1.5-ml/kg per hour threshold and 0.75 (95% confidence interval, 0.68 to 0.81) for the 2-ml/kg per hour threshold.

Conclusions

Early-onset AKI was diagnosed on the basis of urine output exclusively for a quarter of the cases. Furthermore, modified AKI definitions that included higher urine output improved the discriminative performance for predicting mortality.
Economía política de El Mezquital en el marco de las transformaciones agrarias y económicas en Durango durante el Porfiriato
Authors: Quiñones Martínez Cynthia Teresa
Published: June 2022

El presente trabajo expone las particularidades del desarrollo económico del partido de El Mezquital ubicado al sur del estado de Durango, México, en relación con el resto de los partidos de dicho estado a finales del Porfiriato. Se ofrece un panorama de la estructura de la propiedad de la tierra, de la producción agropecuaria y de la composición demográfica de acuerdo con sus ocupaciones; se pone énfasis en la construcción gubernamental de un imaginario en torno a El Mezquital como una zona llena de riqueza forestal y minera aunque hostil social y geográficamente, lo que impactó en la poca exploración y nula inversión económica, así como en la preservación de la propiedad colectiva de los pueblos tepehuanos en el periodo álgido de compraventa de tierras. La historiografía existente se ha centrado en los grandes centros económicos del estado, relegando a El Mezquital precisamente por su poco impacto en la economía estatal; sin embargo, es relevante conocer y entender las características sociales, económicas y geográficas que contribuyeron al particular desarrollo económico de este partido a finales del siglo xix. Las principales fuentes primarias utilizadas son informes de diversos agentes de gobierno y notas de la prensa.
Sobre Carlo Ginzburg y Bruce Lincoln, Old Thiess, a Livonian Werewolf. A Classic Case in Comparative Perspective
Authors: Jacinto Lizette
Published: June 2022

Reseña sobre Carlo Ginzburg y Bruce Lincoln, Old Thiess, a Livonian Werewolf. A Classic Case in Comparative Perspective (Chicago; London: Chicago University Press, 2020).
Sobre Andrea Rodríguez Tapia, Realistas contra insurgentes. La construcción de un consenso historiográfico en el México independiente (1810-1852)
Authors: Martín Blázquez Francisco Miguel
Published: June 2022

Reseña sobre Andrea Rodríguez Tapia, Realistas contra insurgentes. La construcción de un consenso historiográfico en el México independiente (1810-1852) (Bilbao: Servicio Editorial de la Universidad del País Vasco, 2019).
Anomalous Object Detection with Deep Learning
Authors: Poojitha L.
Published: June 2022

Abstract: In many computers vision systems, object identification and monitoring are crucial characteristics. Object identification and monitoring is a difficult job in the fields of computer vision that attempts to identify, recognize and track things across a video series of pictures. It aids in the understanding and description of object behaviour rather than relying on human operators to monitor the computers. Its goal is to find moving things in a video clip or a security camera. On the other hand, rely heavily on computers, on the other hand many respect attributes approaches. The system collects a snapshot from the camera, process it as per the models requirements and the outputs the data to the tensorflow framework which provides a list of the frames discoveries and the objects dependability points and connections to their binding containers. Before exposing the object to the user, the software takes those connections and creates a rectangle adjacent to it. This research detects the presence of anomalous items in camera-captured sequences, with anomalies being things that correspond to categories that should not be present in a given scene.
Early Stage Detection of Autism Spectrum Disorder using Machine Learning
Authors: M Mr. Anand
Published: June 2022

Abstract: Autism Spectrum Disorder is an inescapable neurodevelopmental problem recognized by universal troubles since youth across complementary social correspondence and restricted, redundant notification and ways of behaving. Yet ideal ASD research focused in essentially on kids, there is rising affirmation that ASD is a strong neurodevelopmental disarray. In any case, despite the fact that wellbeing and furthermore instruction administrations for youngsters with ASD are tolerably well established, administration arrangement for grown-ups with ASD is in its start. There is an insufficiency of prosperity organizations research for adults with ASD, including recognizing confirmation of ailments, intensive treatment fundamentals, headway of new blooming pharmacotherapies, solicitation of progress and developing across the future, and considered sex uniqueness and the perspective of people with ASD.
EVALUATION OF TRACE METAL CONTENTS IN MUSHROOM SAMPLES FROM AZDAVAY DISTRICT, KASTAMONU, TURKEY
Authors: ATASOY Muhammet , YILDIZ Dilek
Published: June 2022

Mushrooms are a popular food because they are an important source of essential amino acids, proteins and dietary fibers, but they have a great capacity to accumulate metals from substrate. Due to this reason, the content of 5 trace metals (Fe, Cr, Zn, Pb, Se) of fruit bodies of 21 fungi species originally found in Azdavay, Kastamonu Region, Turkey were analyzed by atomic absorption spectroscopy. The contents of investigated trace metals in mushroom samples were found to be in the range of 4.6–3478.7 mg kg-1 for Fe, 5.1–19.9 mg kg-1 for Cr, 10.4–138.6 mg kg-1 for Zn, 5.8–28.0 mg kg-1 for Pb and 0.65–1.47 mg kg-1 for Se. The relative standard deviations (R.S.D.) were found below 10%. The accuracy of procedure was confirmed by CRMs (BCR 191 Brown bread, ERM-BD 151 Skimmed milk powder).
Acute fatty liver of pregnancy accompanied with disseminated intravascular coagulopathy and encephalopathy: a case report
Authors: Qazi Saba Saleem , danish Shiza , Akhai Anusha , Khwaja Hania , Tahir Muhammad Junaid , Eljack Moh. , Farooqui Sabeeh Khawar , Asghar Muhammad Sohaib
Published: June 2022

Acute fatty liver disease of pregnancy (AFLP) is a rare condition
associated with other common liver manifestations such as hemolysis,
elevated liver enzymes, and low platelets syndrome (HELLP). We present a
27-year-old pregnant woman who developed hepatic encephalopathy and DIC
after being diagnosed with Acute fatty liver disease of pregnancy.
Additively Custom-made 3D Printed Subperiosteal Implants for the rehabilitation of the Severely Atrophic Maxilla (a case report)
Authors: Arshad Mahnaz , Khoramshahi Nourin , Shirani Gholamreza
Published: June 2022

In the past decade, on account of computer-aided prosthetic
manufacturing techniques, subperiosteal implants were introduced as a
safe option for patients with compromised alveolar ridges. We present 3
years follow-up of a complete maxillary rehabilitation by subperiosteal
implants in a young patient after an endosseous implant treatment
failure.
Non-allelic homologous recombination leading to premature transcription termination in the ARSB gene as a novel cause of Mucopolysaccharidosis type VI
Authors: Bychkov Igor , Filatova Alexandra , Baydakova Galina , Sikora Nataliya , Skretnev Alexandr , Tabakov Vyacheslav , Skoblov Mikhail , Zakharova Ekaterina
Published: June 2022

Mucopolysaccharidosis type VI (MPS VI) is a lysosomal storage disorder
associated with pathogenic variants in the ARSB gene. Herein, we
present a novel type of ARSB mutations, which is an insertion of
the LHFPL2 gene fragment derived from unequal non-allelic
homologous recombination between these two genes. The 52 kb insertion,
containing the LHPL2 exon 3, was identified in reverse complement
orientation deep in the intron 4 of ARSB using whole genome
sequencing. Subsequent RNA analysis determined its deleterious effect,
which is premature transcription termination. Two mobile genetic
elements of the L1 class with high sequence similarity were identified
in both genes at the site of recombination and their close spatial
proximity is suggested to favor structural rearrangements in this locus.
The recombination was identified in compound heterozygous state with the
nonsense variant c.966G>A (p.Trp322*) in patient with an
early-onset form of MPS VI. Almost complete absence of the full-length
ARSB mRNA isoform expression from both alleles correlates well
with a severe phenotype of the patient. The results of our study expand
mutational spectrum of the ARSB gene towards complex structural
variants and novel molecular-genetic mechanisms.