bluuebunny/crossref_metadata_2025 huggingface dataset:
Manifestation of ocular tuberculosis in a north Indian tertiary care centre: Case series
Authors: Singh Neha , Singh Praveen
Published: August 2024

Ocular tuberculosis acts as a challenge throughout the world, and its pathophysiology, diagnosis, and treatment are a topic for debate. The present case series represents retrospective study focusing on the variable clinical presentations, the diagnostic and therapeutic characteristics of ocular tuberculosis. We report 12 patients of ocular tuberculosis with variable presentations.

: Retrospective analysis of records of patients diagnosed with ocular tuberculosis from August 2022 till March 2023 was done. Diagnosis of ocular tuberculosis was based on detailed ocular and systemic examination including best corrected visual acuity (BCVA), Slit lamp examination, fundus examination, OCT. The patients presenting with features suggestive of ocular tuberculosis were further investigated with complete blood count (CBC), erythrocyte sedimentation rate (ESR), Monteaux test, Chest X-ray, Cartridge Based Nuclear Amplification Test (CBNAAT) and rheumatological work up.

Out of 12 of ocular tuberculosis patients, 4 were diagnosed with active retinal vasculitis, 3with choroiditis, 3 had panuveitis, and remaining 2 patients had unilateral nodular episcleritis. The diagnosis was based on compatible clinical picture, highly positive Tuberculin skin test and dramatic response to anti-tuberculous drugs. All 12 cases were strongly Mantaux test positive (2 developed injection site ulceration). All cases were started on ATT immediately with pulmonologist consultation and showed clinical improvement after 1 month.

Ocular tuberculosis can have myriad presentations. Positive Mantaux test plays an important role in supporting diagnosis of ocular tuberculosis.
A spectrophotometric analysis of copper and zinc released from stainless steel brackets coated with a combination of copper oxide and zinc oxide nanoparticles in artificial saliva
Authors: Duraisamy Sangeetha , Anandan Nirmala , Patil Digvijay
Published: August 2024

Nanocoating stainless steel orthodontic brackets with a combination of copper and zinc oxide nanoparticles might alter the quantity of ions released from them in saliva. The purpose of the study was to evaluate the quantity of copper and zinc ions released from stainless steel brackets coated with a combination of copper oxide and zinc oxide.

Stainless steel orthodontic brackets (Ormco Mini -Diamond series 0.22” slot, MBT prescription) (ORMCO CORP Glendora, California, USA) (n= 15 in each group) were coated with nanoparticles of copper oxide (Group I) , zinc oxide (Group II) and a combination of copper oxide –zinc oxide (Group III) nanoparticles using a spray pyrolysis method . The quantity of copper and zinc ions released from these three groups of brackets, when stored in artificial saliva and intubated at 37 C was evaluated at 24hrs, 7th day, 14th day and 28th day using an atomic absorption spectrometer.

The three groups of coated brackets released significantly more copper and zinc ions than the uncoated brackets. The copper oxide nanocoated and zinc oxide nano coated stainless steel orthodontic brackets released more copper and zinc ions when compared to the copper oxide - zinc oxide combination nanocoated orthodontic brackets and uncoated brackets. The highest surge of ion release was noted at the 7th day in all the three coated groups for both the ions evaluated.

Brackets coated with a combination of copper oxide and zinc oxide nanoparticles demonstrated reduced levels of copper and zinc ion release in artificial saliva when compared to copper oxide nanocoated brackets and zinc oxide nanocoated brackets.

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Stability of skeletal open bite correction in adult patients by molar intrusion: A meta analysis
Authors: Prakash V. S.  , Sharma Anil , Verma Santosh , Chauhan Arun Kumar
Published: August 2024

To review and compile literature to check the post retention stability of skeletal open bite correction by molar intrusion.

Articles were searched in Electronic database of English literature i.e. PubMed, Cochrane Library, Embase and google scholar.

Titles and abstracts of potential articles with inclusion criteria were examined and included based on consensus agreement.

Abstracts of articles having characteristics that were uncertain were examined, with full article retrieval if necessary. The reference list of the retrieved articles were also searched.

On comparing the mean post treatment and post retention of overbite derived from their respected forest plot graphs, there was 32 percent relapse in the overbite correction.

This study states that skeletal open bite patients treated with molar intrusion have 68 % stability, whereas the intruded molar have a 95% stability.
Severe dental malocclusion in a case of repaired unilateral cleft palate managed by orthodontic mechanotherapy alone
Authors: Kakodkar Sachin S.
Published: August 2024

Cleft palate is a developmental abnormality that perforates the palate, and divides the arch segments producing grave malocclusion. Crossbites, labiolingual displacements, rotations, archform distortion and incompatibility are a few facets characterizing the problem. Teeth may be congenitally missing or periodontally infirm in the vicinity of the breakdown. If the skeletal jaw base discrepancy is not major, orthognathic surgery may be omitted and orthodontic mechanics alone can suffice to manipulate the teeth into a decent occlusion. Restorative work for esthetic embellishment can enhance the overall result, particularly if teeth are malformed. This case report describes how severe dental malocclusion arising from a repaired unilateral cleft palate defect was corrected with a fixed preadjusted edgewise appliance, adorning smile esthetics and boosting the patient’s self-confidence.
Chatbots and Citizen Satisfaction: Examining the Role of Trust in AI-Chatbots as a Moderating Variable
Authors: El Gharbaoui Ouissale El , El boukhari Hayat , Salmi Abdelkader
Published: August 2024

This study seeks to investigate the effect of deploying artificial intelligence (AI)-chatbots on citizen satisfaction within the public sector in Morocco, with a particular emphasis on the moderating variable of trust in AI-chatbots. Through an exploration of this correlation, the study aims to comprehend the way in which the incorporation of AI-chatbots into public services affects the perceptions and levels of satisfaction of citizens, with a great interest in how trust in these technologies could either amplify or lessen the impact of these technologies. The research sheds light on the current landscape of these technologies using a survey that was issued to citizens. The survey reveals that even if chatbots are still in their earliest phases of adoption, they are already meeting citizen expectations.
Mobile Web Application for Durian Orchard Management and Geospatial Data Visualization Using Deep Learning
Authors: Puttinaovarat Supattra , Saeliw Aekarat , Kongcharoen Jinda , Pruitikanee Siwipa , Pengthorn Pimlaphat , Ketkaew Athicha , Khaimook Kanit
Published: August 2024

Durian, a globally popular fruit, is primarily exported by Thailand, making it the foremost contributor to the world market. Nevertheless, there remains a notable absence of a comprehensive platform or application catering to both consumer tourists and businesses seeking domestic purchases. Prior research has highlighted several shortcomings, notably the inability of existing applications to provide location-based search functionality or automatically identify durian plantation plots from digital photographs. Consequently, this study proposes the development of a mobile web application aimed at managing, processing, and visualizing geospatial data pertaining to orchards and durian plantations. Through the integration of mobile technology, geospatial technology, and machine learning, the research endeavours to address these deficiencies. The findings indicate promising results, particularly in the accurate classification of durian plantations using four machine learning algorithms: convolutional neural network (CNN), support vector machine (SVM), random forest, and k-nearest neighbor (KNN). Among these algorithms, CNN exhibited the highest accuracy, achieving a value of 95%, with precision, recall, and f-measure values of 95.55%, 94.44%, and 94.97%, respectively.
Applying Translaryngeal Ultrasonography in Unilateral Vocal Cord Paralysis before Thyroid Cancer Reoperation: A Single Center Study
Authors: Moslemi Sam , Nasiri Shirzad , Sharghi Sina , Yaghoubi Notash Aidin
Published: August 2024

Background: One of the most dangerous complications of thyroid surgery is recurrent laryngeal nerve (RLN) paralysis. The gold standard method to assess this damage is Videolaryngoscopy. However, we aimed to modify this approach by using Translaryngeal Ultrasonography (TLUS). We performed TLUS with a highly trained thyroid sonographer and an endocrine surgeon in 47 patients with recurrent thyroid cancer and unilateral RLN paralysis preoperatively, and compared the results with Videolaryngoscopy. The experienced sonographer identified 45 injuries in 47 patients, and the endocrine surgeon found 39 vocal cord injuries. It appears that TLUS, when performed by experienced practitioners, is a more accurate and safe modality for assessing vocal cord function in the preoperative setting of thyroid cancer reoperation.
GSYH ve Mülteciler Arasında Bir Nedensellik Analizi: Türkiye ve Ürdün Karşılaştırması Örneği
Authors: Alan Mehmet Mubarek , Çelikkaya Süha
Published: August 2024

Bu çalışmada Türkiye ve Ürdün’ün 1965-2020 yılları arasındaki nominal GSYH ve mülteci sayılarından yararlanılarak, ülkelerdeki gayri safi yurtiçi hasıla ile mülteci sayıları arasında nedensellik ilişkisinin olup-olmadığı araştırılmıştır. Ülkeler kendi içlerinde analize tabi tutulmuş ve bu ilişkiyi belirleyebilmek için sırasıyla; birim kök testleri (ADF, PP, KPSS) uygulanmıştır. Durağanlıkları test edilen serilerin Johansen Eş bütünleşme Analizi ile uzun dönem ilişkileri tespit edilmiş ve son aşamada da Granger Nedensellik Testi ile gayri safi yurtiçi hasıla ve mülteci sayıları arasındaki nedensellikler belirlenmiştir. Beklenen sonuç mültecilerin, üretimi simgeleyen gayri safi yurtiçi hasılanın yüksek olduğu ülkelere yönelmesi, bir başka ifade ile gayri safi yurtiçi hasıladan mültecilere doğru bir nedensellik ilişkisinin çıkmasıydı. Ancak çalışma çıktısında elde edilen sonuç beklenenden farklı çıkmıştır. Türkiye ve Ürdün’de çıkan nedensellik ilişkilerinin ters yönlü olduğu tespit edilmiştir. Türkiye’de mülteci sayılarından gayri safi yurtiçi hasılaya doğru bir nedensellik çıkmışken, Ürdün’de gayri safi yurtiçi hasıladan mülteci sayılarına doğru bir nedensellik ilişkisi tespit edilmiştir. Bu iki ülkenin analizinden de gayri safi yurtiçi hasıla ve mülteci sayıları arasında tek yönlü nedensellik olduğu sonucu çıkmıştır.
Tîpolojîya Dem û Cihî ya Çîrokên Gelêrî yên Kurdî
Authors: Subaşı Kenan
Published: August 2024

Çîrokên gelêrî û vegêran du çemkên pir peywendîdar ên edebî ne. Carinan mimkûn e di şûna hev de jî bên bikaranîn. Di eslê xwe de vegêran ji çîrokê berfirehtir e. Loma asayî ye ku carinan ji bo çîrokê vegêran jî bê gotin. Çîrok jî weku vegêraneke devkî yan jî nivîskî reh û rîşên xwe yên pir kevin hene. Heta berî ku çîroka modern ji aliyê vegêranê ve bê xurtkirin û bi gelek pêlên weku modernîzm û postmodernîzmê ve bê dewlemendkirin, çîroka klasîk yan jî gelêrî bi piranî li ser binyateke vegêranî ya sade dihat ristin. Lê ev sadebûn weku stûnên sereke yên vegêranê ne ku her dem di nav deqeke honandî de xuyane. Ev çar stûn weku vegêr/çîrokbêj, karakter, rûdan, dem û cih dikarin bên binavkirin. Me di vê xebatê de çîrokên gelêrî yên Kurdî xisûsen ji aliyê stûna çarem a vegêranê (dem û cih) ve nirxand û di encamê de em gihiştin tîpolojîyeke dem û cihî ya çîrokên gelêrî yên Kurdî. Di vê nirxandinê de me weku rêbaz di hilbijartina çîrokan de senifandina Aarne-Thompson bingeh danî û ji aliyê xurtbûna vegêranê ve di nav çîrokên çapkirî yên Kurdî de piştî xwendineke giştî 18 çîrok hilbijartin. Herwiha di lêhûrbûna dem û cihî ya çîrokan de jî me xisûsen xebata Gerard Genette, Seymour Chatman û Marie-Laure Ryan bingeh girt.
Toxicity standards of biosolid leachate
Authors: Alexandre Rafael Lucas , Manzatto Caroline Menezes , Giacobbo Emilly , Florentino Robert Willian , Martins Kelly Geronazzo
Published: August 2024

Sewage treatment in Brazilian cities generates biosolids that can be useful in the agricultural field, although they pose contamination risks to the environment and to human health. Ecotoxicity tests are essential to ensure the safety of such a use, since they assess biosolids’ toxicity in the soil and in water. The aim of the current study is to assess biosolids leachate phytotoxicity by using lettuce seeds. In order to do so, Petri dishes were used to incubate the seeds, which received the biosolids leachate and remained under controlled temperature conditions, in the dark, for 168 hours. Overall, the herein assessed parameters have evidenced that the biosolids leachate diluted up to 60% had positive effect on (i.e., it stimulated) seedling growth and germination. However, phytotoxic effect was observed when it was applied without any dilution, since it reduced seed germination and growth parameters. Therefore, the lower the leachate concentration, the higher the Lactuca sativa root growth, a fact that highlights the phytotoxic effect of this leachate.
Peningkatan Wawasan Sertifikasi Halal melalui Sosialisasi UU No. 33 Tahun 2014 Pada UMKM di Kecamatan Baron, Nganjuk
Authors: Rizal Rizal Furqan Ramadhan , Nourmanita Neny Ayu , Rosyidiana Hafidz
Published: August 2024

Kecamatan Baron merupakan salah satu kecamatan di kabupaten Nganjuk yang memiliki jumlah UMKM cukup banyak namun masih banyak produknya yang belum tersertifikasi halal sehingga perlu adanya kegiatan pengabdian masyarakat yang fokus pada sosialisasi sertifikasi halal. Tujuan dari kegiatan pengabdian supaya pelaku UMKM di Kecamatan Baron mendaftarkan produknya supaya resmi tersertifikasi halal oleh MUI. Metode Pengabdian yang digunakan adalah metode ABCD yang terdiri dari 5 tahapan kemudian diterapkan pada kegiatan pengabdian. Untuk mengukur tingkat pemahaman para peserta FGD terhadap sertifikasi halal dilakukan penyebaran kuisioner dan menghasilkan nilai yang signifikan yakni 47% menjadi 78%. Peningkatan pemahaman pelaku UMKM di Kecamatan Baron diikuti dengan kesadaran mendaftarkan usahanya kepada fasilitator sertifikasi halal dengan dibantu oleh para mahasiswa KKN UIN Sayyid Ali Rahmatullah Tulungagung.
Impact of internal phase volume on the physical, morphological and mechanical characteristics of emulsion templated scaffolds
Authors: Aldemir Dikici Betül
Published: August 2024

Objectives: The high porosity of tissue engineering scaffolds is advantageous as they provide a high degree of infiltration of nutrients, enable cell penetration, and support vascularisation. However, the mechanical strength is also critical for providing structural support to the defect site throughout the regeneration process. In this study, we aimed to establish a relationship between internal phase volume and emulsion-templated scaffolds' physical, morphological and mechanical characteristics.
Methods: In this work, tetra methacrylate functionalised polycaprolactone (4PCLMA) polymers were synthesised via ring-opening polymerisation followed by methacrylation. 4PCLMA-based emulsion templated matrices with 60%, 75% and 82% internal phase volumes were fabricated (P60, P75, and P82). These scaffolds' densities, porosities, average pore and window sizes, degree of interconnectivity values, and mechanical properties were investigated.
Results: Increasing internal phase volume reduced the density of the foams by almost two-fold. No direct correlation was observed between average pore size and internal phase volume. Both the average window sizes and the degree of interconnectivity values increase with increasing internal phase volume. Compression modulus values are calculated as 0.46±0.04 MPa, 0.23±0.02 MPa and 0.14±0.01 MPa for P60, P75, and P82, respectively. Increasing internal phase volume from 60% to 82% caused a more than 2-fold reduction in the stiffness of the emulsion-templated matrices.
Conclusions: Accordingly, by reporting on this experimental framework, we established a relationship between internal phase volume and the physical, morphological and mechanical characteristics of 4PCMA-based scaffolds to precisely engineer these characteristics for specific tissue engineering applications.
Descrição, importância e pesquisa sobre programas de reforço: explicando a personalidade, ordenando os comportamentos e esclarecendo sentimentos
Authors: Costa Carlos Eduardo , Banaco Roberto Alves , Becker Rodrigo Morande , Luiz André Connor de Méo
Published: August 2024

Programas de reforço estão na base da vasta maioria dos comportamentos dos organismos e, portanto, conhecê-los é de suma importância para todo analista do comportamento. O presente artigo pretende apresentar uma introdução dos programas de reforço positivo que todo estudante de Análise do Comportamento deveria conhecer. A proposta é começar do simples – visando estudantes de graduação e pós-graduação – mas permitir o estudo aprofundado por meio de das diversas citações e referências contidas no presente trabalho. O artigo fornece exemplos para além do laboratório em cada programa de reforço descrito – procurando levar o leitor a entender a relação entre o tema central e a construção da personalidade e os possíveis sentimentos engendrados – além de trazer assuntos relacionados, tais como: o conceito de contingência, operações motivadoras (ou estabelecedoras) e abolidoras, procedimentos de teste discreto e de operante livre.
O fenômeno do morrer na novela “A morte de Ivan Ilitch” de Lev Tolstói: uma análise fenomenológico-psicológica das vivências psíquicas
Authors: Goto Tommy Akira , Silva Heitor Henrique Nunes
Published: August 2024

O artigo aborda a relação entre a Psicologia e a Literatura, destacando a influência mútua entre essas disciplinas desde o final do século XIX até os dias atuais. Autores como S. Freud e C.G. Jung utilizaram obras literárias para embasar suas teorias, enquanto a Literatura, por sua vez, foi influenciada pelo avanço psicológico, explorando temas relacionados à natureza humana. O trabalho investiga o “fenômeno do morrer” na novela “A morte de Ivan Ilitch” de Lev Tolstói, analisando as vivências psíquicas do protagonista diante desse processo. Para obtenção e manipulação dos dados, a presente pesquisa utilizou-se da proposta “pesquisa fenomenológico-empírica” apresentada por Giorgi e Souza (2010), e ampliada por Goto (2022). Utilizando a metodologia fenomenológico-empírica, foram identificadas as vivências psíquicas de dor física, sofrimento psíquico afetivo e a consciência de uma vida sem sentido. A fundamentação teórica baseou-se na Fenomenologia e na Psicologia Fenomenológica de Husserl. O estudo contribui para a compreensão das vivências psíquicas relacionadas à morte e destaca a importância da interdisciplinaridade entre a Psicologia e a Literatura na análise dos aspectos humanos mais profundos.
Gender Performativity in Sports and Physical Education
Authors: Larsson Håkan
Published: August 2024

The purpose of Gender Performativity in Sports and Physical Education is to explore a perspective of gender called gender performativity. The notion of gender performativity was coined by Judith Butler in the early 1990s. It starts from the ide a that gender is something people do rather than something they are. Such a perspective offers new ways of understanding gender, and therefore also gender equity, in sports and physical education. It offers new ways to think about how inequitable practices can change. Empirical illustrations of gender performativity in sports and physical education are mainly drawn from Håkan Larsson's thirty-year research on the matter, but connections are also made to other research in the field.
Pengaruh Model Problem Based Learning (PBL) Terintegrasi Pembelajaran Berdiferensiasi Terhadap Kemampuan Berpikir Kreatif Peserta Didik Pada Mata Pelajaran IPAS Kelas IV di MI Sunan Giri
Authors: Diniyah Ayu Lestari
Published: August 2024

Important skills to master in the 21st century include critical thinking, creative thinking, communication, and collaboration. Creative thinking is the ability to use one's thought processes to generate new ideas and knowledge. Preliminary research indicates that students do not yet possess strong creative thinking skills, as the current teaching models do not facilitate the development of these abilities. To foster students' creative thinking, an integrated Problem Based Learning (PBL) model with differentiated instruction can be utilized. This study aims to determine the effect of the integrated Problem Based Learning (PBL) model with differentiated instruction on the creative thinking abilities of fourth-grade students in the IPAS subject at MI Sunan Giri. This research employs a quantitative experimental method with a Pre-Experimental One-Group Pretest-Posttest design. The results indicate that the integrated Problem Based Learning (PBL) model with differentiated instruction has a significant impact on students' creative thinking abilities, with the average pretest score being 53.23 and the posttest score being 75.32.
Assessing the effectiveness and history of buffer strip implementation in preventing soil sediment and nutrient losses to surface waters
Authors:   Aarhus University, Denmark, Kronvang Brian , Zak Dominik ,   Aarhus University, Denmark, Skarbøvik Eva ,   Norwegian Institute of Bioeconomy Research (NIBIO), Norway, Buseth Blankenberg Anne-Grete ,   Norwegian Institute of Bioeconomy Research (NIBIO), Norway, Stutter Marc ,   The James Hutton Institute, UK
Published: August 2024

Buffer strips are one of the most widely utilised mitigation measures to reduce sediment and nutrient transfer from soil erosion and surface runoff on fields to neighbouring surface waters. Their effectiveness in terms of retaining sediment and nutrients has been documented by numerous experimental studies, with buffer strip width and soil type the most important factors influencing their performance. A recent review of more than 270 experimental studies on the effectiveness of buffer strips showed an average sediment retention amounting to 72%. Similarly, the average retention for total phosphorus and total nitrogen in buffer strips amounted to 75% and 32%, respectively. Newly developed engineered buffer strips have proven to be increasingly efficient at retaining dissolved nutrients transported via tile drainage water. This chapter looks at the history of buffer strips in countries including Denmark, Scotland and Norway, offering valuable insights in to how to improve the uptake of buffer strips.
The Position of Women and Women's Rights in Islamic Family Reform: A Comparison in Indonesia and Tunisia
Authors: Umi Umi Khoirun Nisa , Ummil Fadhliyah Soraya  , Maryani  , Umar Yusuf
Published: August 2024

This research was prepared with the aim of discussing the position and fight for women's rights in the Islamic Family reform (Comparison in Indonesia and Tunisia). Some women demand that their rights be taken away by male hegemony. This theme ultimately falls within the scope of the Holy Quran which is used as a source of legitimization of the relationship between men and women. The research method used in this study is the method of collecting data through library research. Data is collected by gathering information from various sources of literature, including books, magazines, journals, and others. From this research, it can be concluded that the reform of Islamic family law in Indonesia and Tunisia was carried out to answer the needs of the times and especially to raise the degree (status) of women, namely through nurturing, preserving and then fighting for women's rights. Although the minimum standards of marriage and polygamy differ in the two countries, they share a similar principle and goal: the protection of women's rights. Nonetheless, these rights are equivalent by nature in sharia (maqasyid ash-shari'ah), such as the right to mental and psychological health (equivalent to the nature of hifz an-nafs/maintaining the soul), then the right to maintain reproductive health (equivalent to the nature of hifdz al-nasl/maintaining offspring), Furthermore, the right to obtain equal opportunities in the field of education (commensurate with the nature of hifdz al-'aql / preserving the intellect) and the provisions of polygamy between the two countries also have commensurate goals and principles, namely to protect women's honor or human rights (commensurate with the principle of hifdz al-'ird).
MANAJEMEN DAKWAH MUHAMMAD IBN ABD AL-WAHHAB (KAJIAN SOSIO-HISTORIS)
Authors: Hamidah Hamidah
Published: August 2024

Muhammad ibn ‘Abd al-Wahhab memilih perbaikan aqidah sebagai sasaran awal perjuangan dakwahnya. Ia tidak memulai perjuangannya de-ngan perbaikan politik atau sosial dan ekonomi masyarakat. Karena aqidah masyarakat Nejed khususnya pada saat itu telah rusak, paham animisme pun masih mempengaruhi keyakinan umat. Mereka kembali ke masa Jahi-liyah, sehingga di samping beribadah kepada Allah, mereka juga mengerjakan perbuatan-perbuatan keberhalaan, berziarah ke sebatang kurma, batu tertentu, dan sebagainya yang diyakini mempunyai kekuatan gaib. Di samping itu mayoritas muslim Nejed telah dipengaruhi oleh kepercayaan sekte Syi’ah yang terlalu mengagung-agungkan orang-orang soleh, sehingga keluar dari batas penghormatan sebagaimana yang diajarkan Rasulullah s.a.w.Persoalan aqidah merupakan hal yang pokok. Ia berkeyakinan bahwa jika aqidah masyarakat itu baik dan bersih, maka segi-segi kehidupan lainnya akan menjadi baik, karena aqidah adalah ruh kehidupan keagamaan yang sekaligus ruh kehidupan dunia. Untuk mewujudkan tujuan perjuangan dakwahnya, Muhammad ibn ‘Abd al-Wahhab menempuh cara dakwah: dakwah bil lisan, bil hal dan bil qolam.
Kata Kunci: Manajemen Dakwah, Muhammad Ibn Abd al-Wahhab
The role of inflammatory response in the development of atherosclerosis, myocardial infarction, and remodeling
Authors: Botros Monica , Fadah Kahtan , Mukherjee Debabrata
Published: August 2024

Inflammation is an intrinsic part of the body’s immune response, significantly influencing a myriad of physiological and pathological processes. There is now clinical and experimental evidence suggesting that inflammation accelerates atherosclerosis and its associated complications. The presence of macrophages, T and B cells inside the atherosclerotic plaque fueled this concept and steered subsequent research endeavors toward understanding the pathophysiology of atherosclerosis including plaque formation and destabilization leading to plaque rupture resulting in myocardial injury and remodeling. Understanding the mechanism behind atherosclerosis will aid in developing appropriate treatment interventions. Shifting research and drug development from a singular focus on cholesterol-lowering agents to include adjunctive anti-inflammatory therapies is crucial. Targeting a root cause, i.e., inflammation, will help decrease the incidence and progression of atherosclerosis and improve patient outcomes. In this review, we aim to discuss the current understanding of the intricate role of inflammation in the pathogenesis of atherosclerosis, myocardial infarction, and cardiac remodeling. This synthesis will encompass an exploration of the various inflammatory cells involved, the intricate network of chemokines orchestrating inflammatory responses, and the pathways that underpin these cardiovascular conditions. Furthermore, we will explore promising diagnostic and therapeutic strategies aimed at addressing inflammation in cardiovascular diseases. These include interventions such as colchicine, monoclonal antibodies, and nanoparticles designed to deliver and accumulate drugs at the molecular level within cells.
Analisis Kecelakaan Lalu Lintas (Ruas Jalan Km 10 - Km 17 Gambut)
Authors: Adawiyah Robiatul , Rahmatullah Rahmatullah , Surya Adhi
Published: August 2024

Dengan segala perkembangan yang terjadi , tentu muncul beberapa masalah transportasi salah satunya kecelakaan lalu lintas. Mulai dari kecelakaan ringan, kecelakaan berat yang banyak menimbulkan kerugian materi dan korban jiwa. Tujuan penelitian ini adalah Untuk mengetahui jumlah angka kecelakaan lalu lintas dan daerah rawan kecelakaan lalu lintas di Ruas Jalan Km 10 – Km 17 Gambut. Dalam menganalisis kecelakaan lalu lintas di lokasi penelitian, diperlukan data-data yang mendukung penelitian yaitu data sekunder yang diperoleh dari Kepolisian Resort Banjar. Hasil penelitian Jumlah angka kecelakaan lalu lintastahun 2019 yang terjadi di Ruas Jalan Km 10 – Km 17 Gambut sebanyak 31 kali dengan korban luka berat 0 %, luka ringan 74 %, meninggal dunia 26 %. Titik daerah rawan kecelakaan di Ruas Jalan Km 10 – Km 17 Gambut berada segmen 1 ( km 10 – km 11 ), segmen 2 ( km 11 – km 12 ), segmen 3 ( km 12 – km 13 ), segmen 5 ( km 14 – km 15 ). Diharapkan kepada semua pengguna jalan tetap berhati-hati dan untuk Pemerintah terkait agar ada perawatan dan pemeliharaan pada setiap ruas jalan yang kurang mendapatkan perawatan karena lingkungan jalan juga berpengaruh dalam kecelakaan lalu lintas.
Pengaruh Pemanfaatan Claystone Sebagai Alternatif Bahan Pengganti Agregat Halus Terhadap Kualitas Paving Block
Authors: Putranto Fikry Pandu , Prasetia Irfan
Published: August 2024

Claystone adalah batuan yang pada umumnya bersifat plastis, berkomposisi hidrous alumunium silikat (2H2OAL2O32SiO2) atau mineral lempung yang mempunyai ukuran butir halus. Pada saat dilakukan pembangunan TPA Regional Banjarbakula ditemukan cukup banyak material claystone, dimana ada sekitar lebih dari 8000 m3 claystone. Karena tidak dimanfaatkan dengan cukup baik, sebagian besar claystone tersebut dibuang dan dipindahkan dari TPA Regional Banjarbakula. Berdasarkan hal tersebut maka perlu dilakukan pemanfaatan, agar apabila ditemukan lagi material claystone dalam jumlah yang besar tidak akan terbuang sia-sia dan dapat dimanfaatkan dengan optimal. Penelitian ini dilakukan untuk mengetahui pengaruh claystone yang ditemukan di TPA Regional Banjarbakula sebagai alternatif bahan pengganti agregat halus terhadap kualitas paving block dan mengetahui campuran yang optimum. Pada pembuatan sampel paving block variasi claystone yang digunakan sebanyak 0%, 25%, 50%, 75%, dan 100% dengan FAS 0,4. Pengujian kuat tekan sampel paving block dilakukan pada umur 7 dan 28 hari. Berdasarkan hasil pengujian kuat tekan, nilai kuat tekan paving block dengan campuran claystone 25% pada umur 28 hari sebesar 18,08 Mpa memiliki nilai kuat tekan yang paling mendekati kekuatan paving block normal atau tanpa campuran claystone sebesar 18,24 Mpa. Kekuatan dari paving block dengan campuran claystone bisa semakin meningkat seiring dengan lamanya waktu curing.
Analisis Neraca Air Sub Das Martapura
Authors: Miranti Febry Asthia , Rahmadania Meireinda
Published: August 2024

Sungai Martapura merupakan Sungai yang melintasi Kabupaten Banjar dan Kota Banjarmasin yang termasuk dalam DAS. Sungai ini bermuara ke Sungai Barito yang bagian hulunya merupakan persimpangan antara Sungai Riam Kiwa dan Sungai Riam Kanan. Sub DAS E merupakan bagian dari Sub DAS Martapura. Neraca air merupakan analisis hasil pendekatan terhadap nilai-nilai proses hidrologi yang terjadi di lapangan. Metode Neraca Air (Water Balance) membandingkan antara ketersediaan air dengan kebutuhan air yang ada. Tujuan dari penelitian ini adalah tersedianya perhitungan neraca air yang dapat dijadikan dasar untuk menghasilkan konsep alokasi air dalam bentuk rencana penyediaan air tahunan. Analisa ketersediaan air didasarkan pada perhitungan debit aliran dasar hasil perhitungan FJ Mock. Didapatkan hasil perhitungan Neraca Air pada debit tahun kering (80%) mengalami surplus.
Pengaruh Sudut Bukaan Heksagonal Terhadap Kapasitas Geser Castellated Steel Beam
Authors: Barkiah Ida , Darmawan Arya Rizki , Dzikry Muhammad Fitrah
Published: August 2024

Bukaan pada badan castellated steel beam mempengaruhi peningkatan kapasitas lentur balok baja dan kapasitas geser pada profil baja castellated steel beam. Penelitian dilakukan dengan menentukan bentang elemen balok baja konvensional dan castellated steel beam yang memiliki panjang yang sama. Balok baja diberikan pembebanan dua beban terpusat pada dua titik di 1/3 bentang. Penelitian ini menyimpulkan bahwa efek dari geometrik bukaan pada castellated steel beam akan menurunkan kapasitas geser. Pada sudut bukaan heksagonal 45°-50° terjadi penurunan kapasitas geser sekitar 18%. Nilai kapasitas geser optimum terjadi pada sudut bukaan 20° dengan penurunan kapasitas geser sebesar 3%. Pola keruntuhan yang terjadi merupakan tekuk diagonal (tekuk akibat geser) badan di 1/3 bentang.
Studi Penjadwalan Menggunakan Metode CPM dan PDM dengan Microsoft Project 2019 pada Proyek Pembangunan Pondok Darul Hijrah Putera Martapura
Authors: Marina Marina , Kartadipura Retna Hapsari
Published: August 2024

Pada proyek gedung Wisma Darul Hijrah Putera dibuat penjadwalan yang diharapkan dapat membantu berlangsungnya proyek. Untuk itu, digunakan metode Critical Path Method (CPM) dan Presedent Diagram Method (PDM) untuk mendapatkna hasil indeks dari penjadwalan. Dari hasil analisis penelitian ini didapatkan penjadwalan Proyek Pembangunan Gedung Wisma Darul Hijrah Putera yaitu dikerjakan selama 64 bulan 26 hari dengan metode CPM yang dimulai pada tanggal 31 Agustus 2020 dan berakhir pada tanggal 26 januari 2026 serta 14 bulan 18 hari dengan metode PDM yang dimulai pada tanggal 31 Agustus 2020 dan berakhir pada tanggal 18 November 2021. Perbedaan waktu yang besar disebabkan perbedaan penggunaan konstrain pada setiap metode.
Development of Web-Based Building Permit (IMB) Information System
Authors: Noor Muhammad Syarifuddin , Prasetia Irfan
Published: August 2024

An integrated information management system is needed to provide convenience not only for organizers but also can provide information such as completion time, costs, and procedures that can be informed directly and transparently. The purpose of this research is to find out the obstacles faced and to design a web-based building permit (IMB) information system with mobile features to speed up the IMB creation process. The research method used is the waterfall model method. The method used to analyze the problems and constraints in the process of making the IMB by the Frontliner, Head of Section, the Technical Team, and the Head of the IMB by experimenting with the application of the IMB Issuance Information System. From the data that has been obtained, an information system design is carried out with the stages of requirements, design, analysis, design, coding, system implementation, system verification, and validation. The results of this study obtained a web-based IMB information system design to facilitate the process of issuing IMB. With the existence of a management information system, IMB proposals based on the results of verification and validation can be applied and provide convenience and speed up the IMB management process.
Saluran Gendong Sebagai Proteksi Sedimentasi Aliran Permukaan Dari Lahan Tambang Batu Bara Pada Saluran Irigasi D.I. Tapin
Authors: Wirdyanata Gleny Floresa
Published: August 2024

Pembangunan jaringan irigasi D.I. Tapin diproyeksikan akan melayani 5.472 Ha sawah. Dalam pengerjaanya trase saluran irigasi melewati berbagai jenis lahan, antara lain lahan bekas tambang, yang berdampak pada saluran irigasi eksisting terisi lumpur dari lahan bekas tambang batu bara setiap kali musim hujan di ruas BTKN 5 – BTKN 6. Hal ini menyebabkan terputusnya aliran ke hilir. Oleh karena itu diperlukan proteksi saluran irigasi dari aliran permukaan yang membawa material sedimen. Terdapat 2 alternatif solusi yaitu merubah saluran terbuka menjadi saluran tertutup dengan menggunakan struktur gorong – gorong, atau menambah saluran gendong untuk memproteksi saluran irigasi dari aliran permukan (run off) di luar area irigasi. Kedua alternatif tersebut dilakukan analisis biaya, waktu, mutu, metode pelaksanaan, serta operasional dan pemeliharaan. Didapatkan kesimpulan solusi untuk permasalahn ini menggunakan alternatif II yaitu pekerjaan saluran gendong sebagai proteksi sedimentasi aliran permukaan dari lahan tambang batu bara pada Saluran Irigasi D.I. Tapin. Hal ini karena waktu pengerjaan lebih cepat 21 hari, metode pelaksanaan lebih sederhana, Operasional dan pemeliharan lebih mudah, serta biaya lebih besar Rp. 225.490.090 masih dalam batas kewajaran oleh pengguna jasa.
Perubahan Pekerjaan Beton Lining in Situ ke Beton Precast pada Jaringan Irigasi D.I. Tapin Kabupaten Tapin
Authors: Darmawan Hafiz
Published: August 2024

Penilitian ini bertujuan untuk mengevaluasi dan menganalisis perubahan metode pada lining beton pada saluran irigasi, antara beton insitu dan beton Precast. Dengan dilakukannya evaluasi terhadap perubahan metode pekerjaan tersebut akhirnya didapatkan bahwa metode dengan menggunakan beton Precast memiliki beberapa kelebihan dibandingkan beton insitu. Dari segi mutu pelaksanaan, mutu beton menjadi mutu K-225 yang semula hanya beton mutu K-175. Selain itu beton Precast bisa meminimalkan kehilangan/material losses dalam waktu pelaksanaan karena dicetak pada bidang yang presisi, dan waktu pelaksanaan yang secara signifikan bisa lebih cepat.  Pada Analisis biaya penggunaan beton Precast mengalami kenaikan harga yang diakibatkan oleh kenaikan mutu beton, langsir, dan penambahan dowel bar. Namun dari hasil analisis terlihat juga bahwa semakin banyak volume beton Precast maka biaya konstruksi bisa semakin turun.
Pengaruh Kompetensi Manajerial Terhadap Project Performance Pada Proyek Konstruksi Gedung di Jabodetabek
Authors: Imansyah Fatih Nuurahman Putro
Published: August 2024

Proyek konstruksi memiliki sifat keunikan yang berbeda-beda, kompleks, dan penuh ketidakpastian sehingga diperlukan suatu fungsi manajemen yang baik, meliputi kegiatan perencanaan, kegiatan pelaksanaan, dan kegiatan pengendalian. Tidak sedikit proyek konstruksi menimbulkan permasalahan-permasalahan yang berdampak pada keterlambatan penyelesaian proyek. Oleh karena itu diperlukan project performance yang baik melalui empat parameter, yaitu tepat biaya, tepat waktu, sesuai dengan mutu dan safety sehingga dapat meningkatkan kepuasan stakeholder yang terkait dalam pelaksanaan proyek tersebut. Penelitian ini bertujuan untuk menguji pengaruh manajerial terhadap project performance. Jumlah responden dalam penelitian ini adalah sebanyak 112 responden, seluruh responden merupakan para profesional yang bekerja di proyek konstruksi gedung di Jabodetabek (Jakarta, Bogor, Depok, Tangerang dan Bekasi). Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kuantitatif dengan instrumen berupa angket kuesioner. Data penelitian yang diperoleh dari hasil pengisian kuesioner dianalisis dengan menggunakan teknik analisis SEM PLS dengan bantuan program SmartPLS. Hasil penelitian ini menunjukkan bahwa manajerial dapat berpengaruh terhadap project performance.
PEMBANGUNAN DERMAGA SUNGAI TAYAN KABUPATEN SANGGAU DENGAN MEMPERTIMBANGKAN MUKA AIR TERTINGGI SERTA TERENDAH
Authors: Hawinuti Riska , Suprianus Suprianus
Published: August 2024

Dermaga Sungai Tayan sebagai penunjang kegiatan bongkar muat penumpang dan barang via jalur sungai diharapkan mampu meningkatkan taraf hidup dan perekonomian masyarakat, dimana kondisi dermaga pada saat survey awal, memerlukan perbaikan dan peningkatan berupa pekerjaan fisik dermaga dan fasilitas penunjangnya. Tujuan penulisan artikel ini adalah meninjau pekerjaan dermaga terhadap posisi elevasi atas dermaga (EAD) dan muka air tertinggi dan terendah untuk tiap jenis dermaga. Metode yang digunakan adalah observasi langsung pada pekerjaan fisik dermaga bongkar muat, dermaga dolphin dan dermaga sampan. Berdasarkan EAD dan kondisi muka air, direncanakan untuk kapal maksimal 1000 Dead Weight Tonnage (DWT) pada dermaga bongkar muat dan dermaga dolphin; serta, maksimal 7 DWT untuk dermaga sampan. Elevasi untuk dermaga bongkar muat: EAD +100,017 Meter di Atas Permukaan Laut (MDPL); muka air tertinggi +99,670 MDPL; muka air pasang normal +98,017 MDPL dan muka air normal +95,517 MDPL. Untuk dermaga dolpin: EAD +97,170 MDPL; muka air normal +91, 517 MDPL dan muka air rendah +88,267 MDPL. Serta untuk dermaga sampan: EAD +97,170 MDPL; muka air normal +91, 517 MDPL dan muka air terendah +88,267 MDPL. Kedalaman dasar sungai +81,527 MDPL dengan muka air terendah +88,267 MDPL masih dapat digunakan kapal dengan draft < 6,74 m sehingga aman bagi kapal pada saat muka air terendah / surut.
Instalasi Air Bersih dan Air Kotor pada Rusunawa Telaga Gorontalo
Authors: Nento Ilyas Rivaldi U. , Husnan Rawiyah , Alitu Aryati
Published: August 2024

Air bersih merupakan air yang digunakan untuk keperluan sehari-hari dan dapat dikonsumsi, sedangkan air kotor merupakan air limbah hasil dari aktifitas manusia dan tidak dapat dikonsumsi. Adanya penyaluran air bersih dan air kotor diperlukan demi kepentingan penghuninya. Penelitian ini bertujuan untuk menganalisis kebutuhan air bersih dan air kotor pada Gedung Rusun Telaga Gorontalo sesuai dengan perhitungan yang dilakukan serta instalas air bersih dan air kotor. Hasil analisis dilakukan dengan menggunakan metode survey dan melihat siteplan yang tersedia. Terdapat 42 unit rumah dengan tipe 36 yang terbagi menjadi 3 lantai dengan luas unit total sebesar 1.512 m2, memiliki jumlah penghuni sebanyak 168 orang, dengan nilai kebutuhan air per orang (Qr) sebesar 100 liter/orang/hari. Hasil analisis menunjukkan bahwa kebutuhan air bersih Rusun Telaga Gorontalo sebesar 20,16 m3/hari, limbah air buangan yang dihasilkan sebesar 13,44 m3/hari dan volume septictank yang dihaslikan sebesar 35,12 m3. Untuk instalasi pipa air bersih, beberapa pipa tidak sesuai dengan hasil perhitungan seperti pipa kloset penggelontor kamar dan pipa urinoir tempat wudhu sedangkan untuk instalasi pipa air kotor dan air buangan yang terpasang sudah sesuai dengan hasil perhitungan.
Penggunaan Beton Plastis pada Dinding Halang Tubuh Bendung Proyek Bendungan Jlantah
Authors: Adhi Bagas Wahyu , Markawie Markawie
Published: August 2024

Pondasi  merupakan  bagian  yang  sangat  penting  bagi  suatu struktur tak terkecuali untuk bangunan air seperti bendungan. Perbaikan pondasi bendungan bertujuan agar tegangan tanah yang  timbul  sebagai  akibat  berat  sendiri  dari  bendungan, tekanan air, gaya gempa, dan muatan -muatan yang bekerja tidak  melebihi  daya  dukung  tanah  pondasi  bendungan  di bagian bawah maupun di tebing kiri dan kanan bendungan. Pada Proyek Pembangunan Bendungan Jlantah terdapat permasalahan berkaitan dengan pondasi bendungan. Perbaikan fondasi Bendungan Jlantah semula didesain menggunakan grouting tirai, tetapi dari hasil uji grouting pada bagian palung sungai hasilnya tidak dapat mencapai nilai kekedapan air (Lugeon) yang disyaratkan. Mengingat endapan alluvial dan lapisan batuan yang lapuk kuat masih cukup porus, maka diperlukan perbaikan pondasi secara khusus menggunakan dinding halang (cut-off wall atau diaphragma wall).Tujuan dari penggunaan dinding halang / Diaphragm wall adalah sebagai perkuatan pondasi pada tubuh bending. Metode yang digunakan dalam pembuatan beton plastis adalah trial eror di laboratorium untuk mendapatkan hasil yang sesuai dengan standar. Kesimpulan yang diperoleh dari beton plastis pada dinding halang adalah sudah sesuai dengan standar yang berlaku.
National Medical Commission’s new rule on capping the number of undergraduate medical seats in high performing States: pragmatic or quixotic?
Authors: Venkatachari Mahesh , Arun Babu Thirunavukkarasu
Published: August 2024

The article analyses the recent amendment by the National Medical Commission (NMC) in India, capping the number of undergraduate medical seats in high-performing states, which has sparked a debate. With a healthcare system catering to the diverse needs of 1.4 billion people, regional disparities in healthcare personnel distribution have emerged, especially among doctors. The advantages of the amendment include a focused approach on lagging states and the potential distribution of doctors to improve overall health indices. However, concerns arise over infringement of the autonomy of state governments, potential hindrance to high-performing states, and the impact on doctors' postgraduate choices. This commentary explores the complex factors influencing doctor distribution, including state policies, infrastructure and migration patterns. While emphasising the need for equitable healthcare access, and it also stresses the need for a balanced approach to address the challenges in doctor distribution to ensure both state and national healthcare needs are met effectively.
The Growth Dynamics of King Grass (Pennisetum purpureophoides) in The Application of Beef Cattle Dung Enriched Azolla microphylla
Authors: Hidayat Nur , Prasetyo Prasetyo , Haryoko Imbang , Setiyaningrum Agustinah , Harwanto Harwanto , Ulfah Annistia Rahmadian
Published: August 2024

Research on the cultivation of king grass (Pennisetum purpureophoides) was conducted to obtain information on growth, productivity, and continuity in providing forage for a sustainablee ruminant farming business. One of the cultivation factors is fertilization using beef cow manure as a renewable, inexhaustible natural resource or organic fertilizer. Improving the quality beef manure is important for better stimulation of plant growth and production. Fertilizer can be enriched with Azolla microphylla as a good nitrogen contributor. This study used beef cow dung fertilizer at doses of 10, 20, 30 tons per hectare per defoliation, and Azolla microphylla enrichment by 0%, 10%, and 20 % as treatments in a completely randomized design (CRD). The observed variables were plant growth (plant height, stem diameter, number of plants, and number of leaves as production), every 14 days until harvesting on day 42. The data obtained were analyzed descriptively based on the dynamics of plant growth. The result showed that the growth dynamics of the king grass were strongly influenced by fertilizer and plant’s age but no interaction each other. In conclusion fertilizer made of beef cattle dung enriched with Azolla microphylla is a feasible nitrogen source. The optimum results were obtained from using 30 tons beef cattle dung enriched with 20% Azolla microphylla to fertilize per hectare per defoliation soil.
Evaluation of Onion Peel as Feed Additive on Performance Production Broiler
Authors: Nurul Jannah Saadatin , Edhy Sudjarwo  , Osfar Sjofjan
Published: August 2024

This study evaluated the impact of adding onion (Allium cepa L.), shallot (Allium ascalonicum L.), and garlic (Allium sativum L.) peels as additives to the broiler production. The material used was 189 one-day-old commercial broiler chicken Lohmann strain (unsexing) and assigned to nine treatments and three replications: T0(-): basal diet, T0(+): basal diet + antibiotic (zinc bacitracin 0.1%), T1: basal diet + 0.5% garlic peel, T2: basal diet + 0.5% shallot peel, T3: basal diet + 0.5% onion peel, T4: basal diet + 0.25% garlic peel and 0.25% shallot peel, T5: basal diet + 0.25%. garlic peel + 0.25% onion peel, T6: basal diet + 0.25% shallot peel + 0.25% onion peel, T7: basal diet + 0.167% garlic peel + 0.167% shallot peel + 0.167% onion peel. Feed intake, final body weight, feed conversion ratio (FCR), mortality, productivity index, and income over feed cost were the variables that were observed in the current study.  The data were analysed using Analysis of Variance (ANOVA). The results of the study show that the addition of the three garlic powders do not give any effect (P>0.05) on feed intake, final body weight, FCR, mortality, production index and IOFC. The conclusions of this study showed that garlic peel, shallot peel, and onion peel could be used as feed additive. This choice yields positive effects on production performance, particularly in terms of Feed Conversion Ratio (FCR) and the production index.