bluuebunny/crossref_metadata_2025 huggingface dataset:
Efeitos do uso de gliricídia e rocha fosfatada no crescimento e nos teores de N, P e K nas culturas do quiabo e pepino
Authors: Matos Sandoval Menezes de , Alves Romildo Nicolau , Chaves Josimar da Silva , Soares Ronielly Barbosa , Nascimento João Pedro Santos do , Silva Lucas Souza da , Leal Maria Lorrayne de Araújo , Marzano Ivana Marques , Moraes Gisely Sousa Campos , Souza Fernando Gomes de
Published: June 2021

As exigências nutricionais das hortaliças têm causado aos pequenos e médios produtores familiares prejuízos, com relação à redução da produtividade e a segurança alimentar da sociedade. Neste sentido, objetivou-se avaliar o desenvolvimento de plantas de quiabo (Abelmoschus escurentes L.) e de pepino (Cucumis sativus L.), utilizando esterco de ovinos associado com rocha fosfatada e a leguminosa gliricídia e a quantificação dos teores de N, P e K nas estruturas das plantas. O experimento foi conduzido no Instituto Federal de Ciência e Tecnologia de Roraima - Campus Novo Paraíso, em casa de vegetação, utilizando-se vasos com capacidade de 6 L-¹, preenchidos com solo (Neosolo) coletado da camada de 0-20 cm. O delineamento experimental foi em bloco ao acaso, com os tratamentos arranjados em fatorial 2x2, composto por dois níveis de gliricídia (sem gliricídia (S/G) e (com gliricídia (C/G) e, dois níveis de rocha fosfatada (sem rocha (S/R) e (com rocha (C/R), com quatro repetições, sendo distribuídos nos blocos de forma inteiramente casualizados. Foi adicionado aos vasos uma dose de esterco de ovinos, correspondente a 25 t ha-1. As variáveis determinadas no estudo foram: altura de planta (cm), espessura de caule (mm), número de folhas, diâmetro do fruto (mm), comprimento de fruto (cm), peso de fruto (g) e os teores de N, P e K na planta e nos frutos. Os resultados encontrados para os diferentes tratamentos não apresentaram diferenças. Observou-se que a padronização da fertilidade dos vasos interferiu diretamente nos resultados estatísticos. Desta forma, os agricultores podem renunciar ao uso da folha da gliricídia e da rocha fosfatada, desde que ele tenha esterco de ovinos disponível.
Advocacia do paciente pelos enfermeiros de terapia intensiva: uma revisão integrativa da literatura
Authors: Menezes Jennifer Aguilar Leocádio de , Manoel Mayara Souza , Vargas Mara Ambrosina de Oliveira , Camponogara Silviamar , Brehmer Laura Cavalcanti de Farias , Schneider Dulcinéia Ghizoni
Published: June 2021

Objetivo: Identificar a produção científica acerca do tema advocacia do paciente por enfermeiros no contexto da terapia intensiva entre os anos de 2010 a 2020. Métodos: Revisão integrativa da literatura sobre o tema advocacia do paciente em unidade de terapia intensiva (UTI) entre os anos de 2010 a 2020, realizada nas bases de dados: Publisher Medline (PUBMED), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Cochrane Library e Web of Science, e também na biblioteca eletrônica Scientific Electronic Library Online (SCIELO) Com a busca nas base de dados, e na biblioteca eletrônica, foram encontradas 217 referências, das quais, 18 atenderam aos critérios de inclusão e exclusão da pesquisa. Resultado: Os 18 artigos selecionados foram categorizados conforme os temas identificados com maior recorrência, os quais consistem em: enfermeiro como defensor do paciente e família, barreiras para a defesa do paciente e enfermeiro como articulador entre equipe, paciente e família. Conclusão: Essa revisão possibilita levar ao meio científico, o que vem sendo estudado acerca da advocacia do paciente em UTI nos últimos 10 anos, em âmbito nacional e internacional, além de evidenciar à importância do enfermeiro enquanto defensor dos direitos do paciente e da família, explanar sobre as barreiras existentes para que a advocacia do paciente pelo enfermeiro intensivista ocorra de forma qualificada, e também demonstra como o enfermeiro executa o papel de intermediário entre seu paciente, família e equipe multiprofissional.
As pesquisas abordando Ciências/Biologia em museus: Análise de uma década em revistas científicas
Authors: Almeida Filho Marcos Adelino , Silva Francisca Helenita Oliveira , Arruda Mariny Oliveira , Arruda Mariany Oliveira , Mendes Roselita Maria de Souza , Pantoja Lydia Dayanne Maia , Lucena Eliseu Marlônio Pereira de , Edson-Chaves Bruno , Bonilla Oriel Herrera
Published: June 2021

Os museus são importantes espaços que estimulam a reflexão, a criatividade e auxiliam no processo de construção do conhecimento e no ensino-aprendizagem de professores, alunos e comunidade. O objetivo do presente trabalho consistiu em realizar o estado da arte de artigos científicos dos anos de 2011 a 2020, em revistas de relevância, com a temática de ciências e biologia nos museus brasileiros, por meio de uma análise documental bibliográfica. As revistas analisadas possuem Qualis A1 e A2 da área de Ensino e Educação e foram escolhidas com base na Plataforma Sucupira da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES. Foram encontrados 46 artigos e a partir de suas análises, observou-se que a principal temática encontrada foi a de museus com as áreas de Ciências Naturais/geral, com maiores números de trabalhos no Museu de Astronomia e Ciências afins e Museu Espaço Ciência Viva, sendo a região Sudeste predominante com os estados do Rio de Janeiro e São Paulo. O principal público-alvo das pesquisas foram os funcionários dos museus e os professores do Ensino Fundamental e a análise qualitativa a abordagem mais utilizada. Os resultados encontrados revelam poucos trabalhos desenvolvidos sobre ciências/biologia em museus no Brasil, mas que os trabalhos existentes demonstram diversificação quanto aos espaços museológicos, ferramentas metodológicas para a obtenção dos dados e público-alvo, e reforçam a importância dos museus como locais de democratização da ciência.
Vigilância em Saúde & planejamento e avaliação em Unidades de Saúde da Família: Estudo qualitativo
Authors: Costa Ilka Lorena de Oliveira Farias , Trindade Creusa Barbosa dos Santos , Ferreira Ilma Pastana , Nunes Silvia Ferreira , Santos Valéria Regina Cavalcante dos , Lima Vera Lúcia de Azevedo , Lima Sérgio Beltrão de Andrade , Chaves Elem Cristina Rodrigues
Published: June 2021

Objetivo: Analisar o uso das ferramentas de Vigilância em Saúde, por enfermeiros gerentes, no processo de planejamento e avaliação das equipes da Estratégia Saúde da Família do Nordeste do Pará. Metodologia: Estudo qualitativo com 7 Enfermeiros das Unidades de Saúde da Família. Realizou-se entrevista e análise pelo método de Bardin e IRAMUTEC utilizando a Classificação Hierárquica Descendente e análise de similitude, produzindo seis classes lexicais representadas em Dendograma, considerando palavras com significância (p>0,05), conforme frequência total (f) e qui-quadradro (x²). Resultados foram expressos em Dendrograma, árvore de similitude e recortes das entrevistas em quadros matriciais. Resultados: Obteve-se a clivagem de 151 seguimentos de textos, aproveitando 76,16%, 5361 palavras, 633 ativas, 95 suplementares e média de 35,5 por seguimento. A partir da análise de similitude, percebe-se a palavra “Não” como núcleo central, ligado a “Vigilância em Saúde”, “Saúde” e “Ação”, portanto, inferindo a uma negação, falta, ausência e/ou uma problemática no contexto analisado. Conclusão: A descentralização das responsabilidades entre municípios não oportunizou o desempenho às demandas. Ficam evidentes a não adesão, nos modelos de gerencias e atenção à saúde, das ferramentas de Vigilância em Saúde nas Unidades de Saúde da Família do Nordeste do Pará, portanto, a não adequação das ações e serviços na Estratégia Saúde da Família considerando as características locais.
Hakemlik Mesleğini Sürdürme Ölçeği’nin (HMSÖ) Türkçeye Uyarlama Çalışması
Authors: Karaçam Aydın , Sabuncu Alpar , Akça Elif , Akduman Ozan , Güçlü Hakan
Published: June 2021

Bu araştırmada hakemlik mesleğinin sürdürülmesini etkileyecek, geçerli ve güvenilir, çok yönlü bir ölçeğin Türkçeye uyarlanması amaçlamıştır. Bu bağlamda Ridinger ve ark. (2017) tarafından geliştirilmiş olan “Referee Retention Scale (RRS), “Hakemlik Mesleğini Sürdürme Ölçeği (HMSÖ)”olarak Türkçeye uyarlanmıştır. Araştırmaya 2020-2021 yılında aktif hakemlik yapan 222 kişilik hakem grubu dahil edilmiştir. Bunların %50.5’i (n:112) basketbol, %12.6’sı (n:28) futbol, %24.8’i (n:55) hentbol ve %12.2’si (n:27) voleybol hakemidir. Örneklem grubunun %19.8’i (n:44) kadın, %80.2’sini erkek hakemler oluşturmaktadır. Verilerin çözümlenmesi SPSS 21 ve AMOS programları kullanılarak yapılmıştır. Çeviri-tekrar çeviri tekniği ile Türkçeye çevirisi yapılan ölçeğin yapı geçerliği için temel bileşenler analizi ve varimax döndürme teknikleri kullanılmıştır. HMSÖ’nün ölçüt geçerliği Pearson momentler çarpımı korelasyon katsayısı ile hesaplanmıştır. Bileşenlerin analizi sonucu, öz değerleri 1’den büyük yedi bileşenli bir yapı ortaya çıkmıştır. Ölçek bileşenleri için alfa iç tutarlık katsayılarının birinci faktör için .88, ikinci faktör için .79, üçüncü faktör için .70, dördüncü faktör için .80, beşinci faktör için .70, altıncı faktör için .78 ve yedinci faktör için .70 olarak hesaplanmıştır. Ölçeğin tümü için hesaplanan iç tutarlık katsayısı ise 83’dür. Ölçeğe uygulanan DFA analizi sonucunda x2/sd = 1.784, RMSEA = .06, CFI = .90, GFI = .85, RMR = .10 NFI = .81 ve IFI =90 olduğu görülmüştür.
PERAN DPRD DALAM MEMBANGUN PEMERINTAHAN YANG BAIK DAN BERWIBAWA
Authors: Nurochman Nurochman
Published: June 2021

DPRD Kota Batu  berusaha maksimal membangun pemerintahan daerah yang baik dan berwibawa. Standar baik dan kuat ini terletak terwujudnya suatu pemerintahan yang dapat menjalankan  perintah peraturan perundang-undangan dengan sebaik-baiknya sesuai dengan kepentingan masyarakat di Kota Batu. Penyelenggaraan pemerinatahan daerah  di Kota Batu identik dengan sejumlah pemerintahan daerah di Propinsi lain, yang sama-sama mengandalkan optimalisasi, efektifitas, dan profesionalitas kinerja dewan, sehingga apa yang diperankan oleh DPRD Kota Batu  pun menentukan bangunan pemerintahan sekarang dan mendatang. Oleh karena itu, DPRD Kota Batu  akan berusaha memaksimalisasikan peran yang sudah digariskan oleh norma yuridis.Kata kunci: dewan, peran, yuridis, kinerja, penyelenggaraan The Batu City DPRD tries its best to build good and authoritative regional government. This good and strong standard lies in the realization of a government that can best carry out the orders of laws and regulations in accordance with the interests of the people in Batu City. The implementation of regional government in Kota Batu is identical with a number of regional governments in other provinces, which both rely on the optimization, effectiveness and professionalism of the performance of the council, so that what is played by the Batu City DPRD determines the current and future government buildings. Therefore, the Batu City DPRD will try to maximize the role outlined by juridical norms.Keywords: board, role, juridical, performance, administration
PRO KONTRA KOMPARASI HUKUMAN MATI UNTUK PENGEDAR NARKOTIKA
Authors: Mardhani Candra Tri
Published: June 2021

AbstrakPro kontra soal hukuman mati bagi pengedar narkotika adalah logis. elaksanaan hukuman mati terhadap pengedar narkoba atau tindak pidana pengedaran narkotika di sejumlah Negara juga mempunyai kesamaan dan perbedaan. Persamaannya, bahwa tidak setiap pengedar bisa dijatuhi hukuman mati. Hanya pengedar dengan jumlah tertentu yang bisa dijatuhi dengan sanksi hukuman mati. Mereka (masing-masing Negara) tetap dalam suatu kesepakatan untuk menjadikan pengedar narkoba sebagai ancaman serius bagi kelangsungan hidup bermasyarakat dan bernegara, khususnya dalam merusak dan menghancurkan generasi mudaKata kunci: narkotika, hukuman mati, pengedar AbstractThe pros and cons of the death penalty for narcotics dealers are logical. the implementation of the death penalty for drug dealers or criminal acts of drug trafficking in a number of countries also have similarities and differences. Similarly, not every dealer can be sentenced to death. Only dealers with a certain amount can be sentenced to death penalty. They (each country) remain in an agreement to make drug dealers a serious threat to the survival of society and the state, especially in destroying and destroying the younger generation Keywords: narcotics, death penalty, dealer
HAK ANAK DALAM SISTEM PERADILAN PIDANA ANAK DI INDONESIA
Authors: Ramdani Ramdani
Published: June 2021

Penelitian ini membahas tentang “Hak Anak Dalam Sistem Peradilan Pidana Anak di Indonesia”. Penelitian ini bertujuan untuk mengentahui, menganalisis dan membahasn konsep serta bentuk dari hak anak dalam sistem peradilan pidana anak di Indonesia. Penelitian ini merupakan penelitian normativ dengan menggunakan pendekatan studi kepustakaan dengan menelaah, meneliti dan mengkaji perundang-undangan yang membahas tentang hak anak baik secara konsep maupun bentuk. Hasil dari penelitian ini secara garis besar dapat disimpulkan bahwa anak dalam dalam perkara pidana mendapat jaminan perlindungan hukum dalam berbagai bentuk seperti jaminan keselamatan baik fisik, mental maupun sosial dan memiliki akses terhadap informasi mengenai perkembangan perkara. Anak harus mendapatkan haknya berdasarkan kepentingan terbaik anak penghargaan terhadap anak. Jaminan perlindungan yang didapat tidak hanya dari Undang-undang No 11 tahun 2012 tentang sistem peradilan pidana anak namun juga dari Undang-undang No 13 tahun 2006 tentang perlindungan saksi dan korban. Negara dalam hal ini pemerintah dan aparatur penyelenggara memperhatikan implementasi yang efektif dengan pertimbangan kepentingan terbaik anak.Kata kunci: Sistem peradilan pidana anak, perlindungan anak, hak anakThis research discusses "Children's Rights in the Child Criminal Justice System in Indonesia". This study aims to identify, analyze and discuss the concepts and forms of children's rights in the juvenile justice system in Indonesia. This research is a normative study using a literature study approach by examining, researching and examining laws that discuss children's rights both in concept and form. The results of this study can be broadly concluded that children in criminal cases receive legal protection guarantees in various forms such as safety guarantees both physically, mentally and socially and have access to information regarding case developments. Children must get their rights based on the best interests of the child and respect for the child. The guarantee of protection is obtained not only from Law No. 11 of 2012 concerning the juvenile criminal justice system but also from Law No. 13 of 2006 concerning the protection of witnesses and victims. The state in this case the government and the apparatus organizers pay attention to effective implementation with consideration of the best interests of children.Keywords: Child criminal justice system, child protection, children's rights
Sifat Organoleptik Bakso Pada Berbagai Rasio Perbandingan Daging Sapi Dan Babi
Authors: Hetharia Charliany , Loppies Yerrynaldo , Handu Herman
Published: June 2021

Tujuan penelitian ini adalah untuk mengetahui rasio antara daging sapi dan daging babi yang disukai serta untuk mengetahui pengaruh rasio antara daging sapi dan daging babi terhadap sifat organoleptik bakso yang dihasilkan. Penelitian ini menggunakan rasio presentasi daging sapi dan daging babi yang berbeda yaitu Â P1 (75% daging sapi : 25% daging babi),Â  Â P2 (50% daging sapi : 50% daging babi), P3 (25% daging sapi : 75% daging babi), K1 (kontrol bakso sapi) dan K2 (kontrol bakso babi) Â dan 35 panelis Â sebagai ulangan. Peubah yang diamati adalah sifat organoleptik berupa warna, aroma, tekstur, rasa dan kekenyalan. Data yang diperoleh dianalisa dengan metode Kruskal-Wallis.Hasil penelitian menunjukkan bahwa perlakuan rasio daging sapi dan daging babi berpengaruh nyata pada taraf (P<0,05) terhadap sifat organoleptik warna dan kekenyalan tetapi tidak berpengaruh terhadap sifat organoleptik aroma, rasa dan tekstur. Berdasarkan hasil tersebut maka dapat disimpulkan bahwa rasio antara daging sapi dan daging babi yang disukai serta memberikan pengaruh terhadap sifat organoleptik adalah P2 (50% daging sapi : 50% daging babi)
CHARACTERIZATION OF PHYSICAL AND MECHANICAL PROPERTIES OF BIODEGRADABLE FOAM FROM MAIZENA FLOUR AND PAPER WASTE FOR SUSTAINABLE PACKAGING MATERIAL
Authors: Arya Yudanto Yusuf , Pudjihastuti Isti
Published: June 2021

Biodegradable Foam (Biofoam) production is an
effort to reduce plastic waste in Indonesia. This product is
made to replace Styrofoam, whose raw material is
carcinogenic in the form of styrene which cannot be
dissolved by the digestive system and is difficult to excrete
through urine or feces which can trigger the growth of
cancer in the long term and is harmful to the environment.
Biofoam in this study is made from cornstarch with the
addition of cellulose taken from paper waste. Based on the
research that has been done, cornstarch-based biofoam
with the addition of cellulose from paper waste as a biofiller
can affect the physical and mechanical characteristics of the
biofoam produced. The biofoam with a starch:cellulose
ratio of 13:10 grams resulted in the best value of water
adsorption in the amount 47.26%, also give the best result
on tensile strength value and biodegradability value in the
amount of 4.548 MPa and 11.943%. The addition of
cellulose to the biofoam mixture in an appropriate amount
will reduce the water absorption value of the biofoam.
Because cellulose can cover the cavities generated by the
starch expansion process in the biofoam. Therefore, the
addition of cellulose also affects the mechanical properties
of biofoam, namely tensile strength. Where the low filler
composition in the biofoam will increase the tensile
strength, but when the filler composition has passed an
optimum point, the filler particles will experience
agglomeration thereby reducing the tensile strength of the
biofoam product. The variation in operating conditions in
the manufacture of starch-based biofoam with the addition
of a biofiller in the form of cellulose from paper waste did
not significantly affect it. The variation in operating
conditions only affects the visual appearance of the biofoam
produced. Biofoam samples with the best visual appearance
were produced at an operating temperature of 160 ? with
an operating time of 30 minutes. Where high temperatures
can affect th
Algorithms of Nakhchivan (Azerbaijan) Grasslands and Their Economic-Geographical Assessment, Based on Landscape Planning
Authors: Hasanov A. , Ibrahimova L. , Aliyeva N.
Published: June 2021

According to the article, grasslands amount for 103,816 hectares out of 5,502.78 km2 total area of Nakhchivan AR. The grasslands play a vital role in the development of livestock, especially rearing of bovine animals, small-horned livestock and beekeeping. Descriptive research work has been conducted in the field, in order to determine the role of grasslands in the development of livestock farming. There is a strong need for conducting study of the area on the basis of landscape planning. As a consequence of a series of natural and anthropogenic factors, a number of environmental issues have arisen on grasslands, and as a result, some areas have become unusable. 58,020 hectares or more than 50% of grasslands became unusable. On the other hand, 45,796 hectares are in good condition. It should be outlined that since destructive factors outpower restorative factors, there is a risk of losing grasslands in the future. It is about time to seriously engage in the solution of environmental problems related to grasslands. Otherwise, we will face bitter consequences. Therefore, landscape planning should be applied in every research work. Hierarchical landscape composition of the area and the problems in each composition should be clearly defined, and the solutions should be developed accordingly. Research work is notably topical in this context.
Fundamentals of the Theory of Power Pulse Device
Authors: Niyazov N. , Dzhamankizov N. , Asanov A. , Ismanov Yu.
Published: June 2021

The article discusses a mathematical model of a power impulse device, which allows you to select the characteristics of the ejected liquid jet, such as the velocity at the moment of ejection, the pressure created in the nozzle of the power impulse device, etc., by changing the parameters of the device. A feature of the proposed mathematical model, which significantly distinguishes it from the previously considered models, is that the model was considered for the case of unsteady motion. This state of the medium in a power impulse device is the most characteristic, therefore the results obtained are more general. It is shown that, in contrast to the steady motion of a liquid, in the case of unsteady motion, an additional term appears, which can be defined as a head having an inertial character. It can be seen from the proposed mathematical model that the presence of an inertial head leads to the appearance of a flow deceleration effect, which, in turn, leads to an increase in the total liquid head in the direction of the flow. The pressure generated in the barrel acts against the direction of the hydraulic resistance. All of the above is applicable only for a certain moment in time or for the case when the acceleration of the fluid is constant. If the acceleration changes, then the action of the heads along the fluid flow is a function of time. This circumstance makes it possible to apply the result obtained with unsteady motion to create devices that form a high-pressure jet. A distinctive feature of the considered model is that it analyzes the behavior of the fluid in the power impulse device for two cases: 1. the volume of fluid in the barrel of the power impulse unit is greater than the volume of the nozzle; 2. the volume of fluid in the barrel is less than or equal to the volume of the nozzle. The results of the analysis showed that in the first case, the initial velocity of liquid ejection significantly exceeds this velocity in the second case. That is, it is the first case that is of practical importance.
Well-Placed Acetabular Component Oriented Outside the Safe Zone During Weight-Bearing Daily Activities
Authors: Zheng Nan , Hu Xiangjun , Dimitriou Dimitris , Dai Kerong , Guo Tao , Tsai Tsung-Yuan
Published: June 2021

Background:A comprehensive and thorough understanding of functional acetabular component orientation is essential for optimizing the clinical outcome after total hip arthroplasty (THA). This study aimed to quantify the functional acetabular anteversion and inclination of unilateral THA patients during walking and static standing and to determine whether the functional acetabular orientation falls within the Lewinnek safe zone.

Methods:Seventeen patients with unilateral THA received a CT scan and dual fluoroscopic imaging during level walking and static standing to evaluatein vivohip kinematics. The pelvic functional coordinate system of the 3D CT-based computer model was defined by the line of gravity and anterior pelvic plane (APP) to measure functional acetabular anteversion and inclination in different postures. The Lewinnek safe zone was used to determine the acetabular malposition during functional activities.

Results:The THA side demonstrated an average of 10.1° (± 9.6°, range –7.5° to 29.9°) larger functional anteversion and 16.0° (± 9.2°, range –7.2° to 29.9°) smaller inclination than native hips during level walking. Functional acetabular anteversion in the THA side during level walking and static standing was significantly larger than anatomical measurements (p< 0.05). Acetabular orientation of most well-placed THA components anatomically in the Lewinnek safe zone fell outside the safe zone during more than half of the gait cycle and static standing.

Conclusion:The current study revealed that an anatomically well-placed acetabular cup does not guarantee a well-functional orientation during daily activities. Thein vivomechanical performance and loading conditions of the THA component during other weight-bearing activities should be investigated in further studies.
The Rheology of the Carotid Sinus: A Path Toward Bioinspired Intervention
Authors: Iskander Andrew , Bilgi Coskun , Naftalovich Rotem , Hacihaliloglu Ilker , Berkman Tolga , Naftalovich Daniel , Pahlevan Niema
Published: June 2021

The association between blood viscosity and pathological conditions involving a number of organ systems is well known. However, how the body measures and maintains appropriate blood viscosity is not well-described. The literature endorsing the function of the carotid sinus as a site of baroreception can be traced back to some of the earliest descriptions of digital pressure on the neck producing a drop in blood delivery to the brain. For the last 30 years, improved computational fluid dynamic (CFD) simulations of blood flow within the carotid sinus have demonstrated a more nuanced understanding of the changes in the region as it relates to changes in conventional metrics of cardiovascular function, including blood pressure. We suggest that the unique flow patterns within the carotid sinus may make it an ideal site to transduce flow data that can, in turn, enable real-time measurement of blood viscosity. The recent characterization of the PIEZO receptor family in the sinus vessel wall may provide a biological basis for this characterization. When coupled with other biomarkers of cardiovascular performance and descriptions of the blood rheology unique to the sinus region, this represents a novel venue for bioinspired design that may enable end-users to manipulate and optimize blood flow.
A Correlation Analysis of Construction Site Fall Accidents Based on Text Mining
Authors: Luo Xixi , Liu Quanlong , Qiu Zunxiang
Published: June 2021

Construction site fall accidents are a high-frequency accident type in the construction industry and have received extensive attention from accident causal factor analysis and risk management research, but evaluating the relationship between accident causal factors and unstructured texts remains an area in urgent need of further study. In this paper, an analysis method based on text mining was chosen to analyze and process the collected data of 557 investigation reports of construction site fall accidents in China from 2013 to 2019. First, the accident reports were preprocessed to identify six types and 28 causal factors of fall accidents; subsequently, the 28 causal factors were classified into critical causal factors, subcritical causal factors and general causal factors according to their document frequency. Then, the Apriori algorithm was used to analyze the correlation of construction site fall accidents. Finally, strong association rules were obtained between the accident causal factors and between the causal factors and the types of construction site fall accidents. The results showed that 1) insufficient safety technology training and untimely elimination of hidden danger in safe production were the most frequent accident causal factors in fall accident reports. 2) There were different degrees of strong and weak correlations among the causal factors of construction site fall accidents, among which the higher the importance was, the stronger the correlation. 3) There were strong potential laws between the causal factors and the types of fall accidents, and the combination of some causal factors was most likely to lead to the occurrence of the corresponding accident types. This study scientifically and logically elucidated the inherent risk factors for fall accidents, which provides a theoretical basis for preventing fall accidents in construction projects.
Epigenetic Reprogramming Mediated by Maternal Diet Rich in Omega-3 Fatty Acids Protects From Breast Cancer Development in F1 Offspring
Authors: Abbas Ata , Witte Theodore , Patterson William L. , Fahrmann Johannes F. , Guo Kai , Hur Junguk , Hardman W. Elaine , Georgel Philippe T.
Published: June 2021

Diets rich in omega-3 fatty acids (FA) have been associated with lowered risks of developing certain types of cancers. We earlier reported that in transgenic mice prone to develop breast cancer (BCa), a diet supplemented with canola oil, rich in omega-3-rich FA (as opposed to an omega-6-rich diet containing corn oil), reduced the risk of developing BCa, and also significantly reduced the incidence of BCa in F1 offspring. To investigate the underlying mechanisms of the cancer protective effect of canola oil in the F1 generation, we designed and performed the present study with the same diets using BALB/c mice to remove any possible effect of the transgene. First, we observed epigenetic changes at the genome-wide scale in F1 offspring of mothers fed diets containing omega-3 FAs, including a significant increase in acetylation of H3K18 histone mark and a decrease in H3K4me2 mark on nucleosomes around transcription start sites. These epigenetic modifications contribute to differential gene expressions associated with various pathways and molecular mechanisms involved in preventing cancer development, including p53 pathway, G2M checkpoint, DNA repair, inflammatory response, and apoptosis. When offspring mice were exposed to 7,12-Dimethylbenz(a)anthracene (DMBA), the group of mice exposed to a canola oil (with omega 3 FAs)-rich maternal diet showed delayed mortality, increased survival, reduced lateral tumor growth, and smaller tumor size. Remarkably, various genes, including BRCA genes, appear to be epigenetically re-programmed to poise genes to be ready for a rapid transcriptional activation due to the canola oil-rich maternal diet. This ability to respond rapidly due to epigenetic potentiation appeared to contribute to and promote protection against breast cancer after carcinogen exposure.
Bone-Derived Modulators That Regulate Brain Function: Emerging Therapeutic Targets for Neurological Disorders
Authors: Chen Hongzhen , Shang Dewei , Wen Yuguan , Liang Chao
Published: June 2021

Bone has traditionally been regarded as a structural organ that supports and protects the various organs of the body. Recent studies suggest that bone also acts as an endocrine organ to regulate whole-body metabolism. Particularly, homeostasis of the bone is shown to be necessary for brain development and function. Abnormal bone metabolism is associated with the onset and progression of neurological disorders. Recently, multiple bone-derived modulators have been shown to participate in brain function and neurological disorders, including osteocalcin, lipocalin 2, and osteopontin, as have bone marrow-derived cells such as mesenchymal stem cells, hematopoietic stem cells, and microglia-like cells. This review summarizes current findings regarding the roles of these bone-derived modulators in the brain, and also follows their involvement in the pathogenesis of neurological disorders. The content of this review may aide in the development of promising therapeutic strategies for neurological disorders via targeting bone.
miR-548d-3p Alters Parasite Growth and Inflammation in Leishmania (Viannia) braziliensis Infection
Authors: Souza Marina de Assis , Ramos-Sanchez Eduardo Milton , Muxel Sandra Márcia , Lagos Dimitris , Reis Luiza Campos , Pereira Valéria Rêgo Alves , Brito Maria Edileuza Felinto , Zampieri Ricardo Andrade , Kaye Paul Martin , Floeter-Winter Lucile Maria , Goto Hiro
Published: June 2021

American Tegumentary Leishmaniasis (ATL) is an endemic disease in Latin America, mainly caused in Brazil byLeishmania (Viannia) braziliensis. Clinical manifestations vary from mild, localized cutaneous leishmaniasis (CL) to aggressive mucosal disease. The host immune response strongly determines the outcome of infection and pattern of disease. However, the pathogenesis of ATL is not well understood, and host microRNAs (miRNAs) may have a role in this context. In the present study, miRNAs were quantified using qPCR arrays in human monocytic THP-1 cells infectedin vitrowithL. (V.) braziliensispromastigotes and in plasma from patients with ATL, focusing on inflammatory response-specific miRNAs. Patients with active or self-healed cutaneous leishmaniasis patients, with confirmed parasitological or immunological diagnosis, were compared with healthy controls. Computational target prediction of significantly-altered miRNAs fromin vitro L. (V.) braziliensis-infected THP-1 cells revealed predicted targets involved in diverse pathways, including chemokine signaling, inflammatory, cellular proliferation, and tissue repair processes. In plasma, we observed distinct miRNA expression in patients with self-healed and active lesions compared with healthy controls. Some miRNAs dysregulated during THP-1in vitroinfection were also found in plasma from self-healed patients, including miR-548d-3p, which was upregulated in infected THP-1 cells and in plasma from self-healed patients. As miR-548d-3p was predicted to target the chemokine pathway and inflammation is a central to the pathogenesis of ATL, we evaluated the effect of transient transfection of a miR-548d-3p inhibitor onL. (V.) braziliensisinfected-THP-1 cells. Inhibition of miR-548d-3p reduced parasite growth early after infection and increased production of MCP1/CCL2, RANTES/CCL5, and IP10/CXCL10. In plasma of self-healed patients, MCP1/CCL2, RANTES/CCL5, and IL-8/CXCL8 concentrations were significantly decreased and MIG/CXCL9 and IP-10/CXCL10 increased compared to patients with active disease. These data suggest that by modulating miRNAs,L. (V.) braziliensismay interfere with chemokine production and hence the inflammatory processes underpinning lesion resolution. Our data suggest miR-548d-3p could be further evaluated as a prognostic marker for ATL and/or as a host-directed therapeutic target.
Potential Therapeutic Targeting of lncRNAs in Cholesterol Homeostasis
Authors: Ye Wen-Chu , Huang Shi-Feng , Hou Lian-Jie , Long Hai-Jiao , Yin Kai , Hu Ching Yuan , Zhao Guo-Jun
Published: June 2021

Maintaining cholesterol homeostasis is essential for normal cellular and systemic functions. Long non-coding RNAs (lncRNAs) represent a mechanism to fine-tune numerous biological processes by controlling gene expression. LncRNAs have emerged as important regulators in cholesterol homeostasis. Dysregulation of lncRNAs expression is associated with lipid-related diseases, suggesting that manipulating the lncRNAs expression could be a promising therapeutic approach to ameliorate liver disease progression and cardiovascular disease (CVD). However, given the high-abundant lncRNAs and the poor genetic conservation between species, much work is required to elucidate the specific role of lncRNAs in regulating cholesterol homeostasis. In this review, we highlighted the latest advances in the pivotal role and mechanism of lncRNAs in regulating cholesterol homeostasis. These findings provide novel insights into the underlying mechanisms of lncRNAs in lipid-related diseases and may offer potential therapeutic targets for treating lipid-related diseases.
Measuring Urban Vibrancy of Residential Communities Using Big Crowdsourced Geotagged Data
Authors: Wang Pengyang , Liu Kunpeng , Wang Dongjie , Fu Yanjie
Published: June 2021

The pervasiveness of mobile and sensing technologies today has facilitated the creation of Big Crowdsourced Geotagged Data (BCGD) from individual users in real time and at different locations in the city. Such ubiquitous user-generated data allow us to infer various patterns of human behavior, which helps us understand the interactions between humans and cities. In this article, we aim to analyze BCGD, including mobile consumption check-ins, urban geography data, and human mobility data, to learn a model that can unveil the impact of urban geography and human mobility on the vibrancy of residential communities. Vibrant communities are defined as places that show diverse and frequent consumer activities. To effectively identify such vibrant communities, we propose a supervised data mining system to learn and mimic the unique spatial configuration patterns and social interaction patterns of vibrant communities using urban geography and human mobility data. Specifically, to prepare the benchmark vibrancy scores of communities for training, we first propose a fused scoring method by fusing the frequency and the diversity of consumer activities using mobile check-in data. Besides, we define and extract the features of spatial configuration and social interaction for each community by mining urban geography and human mobility data. In addition, we strategically combine a pairwise ranking objective with a sparsity regularization to learn a predictor of community vibrancy. And we develop an effective solution for the optimization problem. Finally, our experiment is instantiated on BCGD including real estate, point of interests, taxi and bus GPS trajectories, and mobile check-ins in Beijing. The experimental results demonstrate the competitive performances of both the extracted features and the proposed model. Our results suggest that a structurally diverse community usually shows higher social interaction and better business performance, and incompatible land uses may decrease the vibrancy of a community. Our studies demonstrate the potential of how to best make use of BCGD to create local economic matrices and sustain urban vibrancy in a fast, cheap, and meaningful way.
Onsite Early Prediction of PGA Using CNN With Multi-Scale and Multi-Domain P-Waves as Input
Authors: Hsu Ting-Yu , Huang Chao-Wen
Published: June 2021

Although convolutional neural networks (CNN) have been applied successfully to many fields, the onsite earthquake early warning by CNN remains unexplored. This study aims to predict the peak ground acceleration (PGA) of the incoming seismic waves using CNN, which is achieved by analyzing the first 3 s of P-wave data collected from a single site. Because the amplitude of P-wave data of large and small earthquakes can differ, the multi-scale input of P-wave data is proposed in this study in order to let the CNN observe the input data in different scales. Both the time and frequency domains of the P-wave data are combined into multi-domain input, and therefore the CNN can observe the data from different aspects. Since only the maximum absolute acceleration value of the time history of seismic waves is the target output of the CNN, the absolute value of the P-wave time history data is used instead of the raw value. The proposed arrangement of the input data shows its superiority to the one directly inputting the raw P-wave data into the CNN. Moreover, the predicted PGA accuracy using the proposed CNN approach is higher than the one using the support vector regression approach that employed the extracted P-wave features as its input. The proposed CNN approach also shows that the accuracy of the predicted PGA and the alert performances are acceptable based on data from two independent and damaging earthquakes.
Anthropogenic Noise and Its Footprint on ELF Schumann Resonance Recordings
Authors: Tritakis V. , Contopoulos I. , Florios C. , Tatsis G. , Christofilakis V. , Baldoumas G. , Repapis C.
Published: June 2021

A set of various short artificial disturbances from rifle firings, car engine operation, car radio, shakings of the apparatus, etc., were generated deliberately near our ELF recording stations in order to identify their footprint on the recordings of atmospheric electromagnetic radiation in the Schumann resonance (SR) band (from about 2–50 Hz). Such disturbances simulate anthropogenic noises from hunters, hikers, campers, etc., which may occur in a remote-isolated ELF recording station. We expect that our work will assist fellow scientists to differentiate between artificial signals created from anthropogenic activity and real signals attributable to geophysical phenomena.
Rise of the Colorado Plateau: A Synthesis of Paleoelevation Constraints From the Region and a Path Forward Using Temperature-Based Elevation Proxies
Authors: Heitmann Emma O. , Hyland Ethan G. , Schoettle-Greene Philip , Brigham Cassandra A. P. , Huntington Katharine W.
Published: June 2021

The Colorado Plateau’s complex landscape has motivated over a century of debate, key to which is understanding the timing and processes of surface uplift of the greater Colorado Plateau region, and its interactions with erosion, drainage reorganization, and landscape evolution. Here, we evaluate what is known about the surface uplift history from prior paleoelevation estimates from the region by synthesizing and evaluating estimates 1) in context inferred from geologic, geomorphic, and thermochronologic constraints, and 2) in light of recent isotopic and paleobotanical proxy method advancements. Altogether, existing data and estimates suggest that half-modern surface elevations were attained by the end of the Laramide orogeny (∼40 Ma), and near-modern surface elevations by the mid-Miocene (∼16 Ma). However, our analysis of paleoelevation proxy methods highlights the need to improve proxy estimates from carbonate and floral archives including the ∼6–16 Ma Bidahochi and ∼34 Ma Florissant Formations and explore understudied (with respect to paleoelevation) Laramide basin deposits to fill knowledge gaps. We argue that there are opportunities to leverage recent advancements in temperature-based paleoaltimetry to refine the surface uplift history; for instance, via systematic comparison of clumped isotope and paleobotanical thermometry methods applied to lacustrine carbonates that span the region in both space and time, and by use of paleoclimate model mediated lapse rates in paleoelevation reconstruction.
Effective Teaching Practices for Success During COVID 19 Pandemic: Towards Phygital Learning
Authors: Chaturvedi Shakti , Purohit Sonal , Verma Meenakshi
Published: June 2021

Following the outbreak of COVID 19 in February 2020, Indian universities were shut down and used digital platforms to teach their students since then. Drawing from Kolb’s Learning Theory, John Dewey’s theory, Jack Mezirows transformative learning theory, and Jean Piaget’s theory, the authors in this paper offer a viewpoint on some of the practical teaching practices which can be adapted in business schools in India to be successful in this emerging blended or phygital environment. Using a Community of Inquiry (CoI) framework, the authors reflect on the effective teaching practices based on their own experience, theoretical knowledge gained from an exhaustive web search of various databases of the period, particularly from February to August 2020. The authors performed a careful manual content analysis of the selected research papers. They concluded seven principal teaching methods to create an effective blended environment for students and faculties in Indian business schools: a) reframing virtual spaces in India through online knowledge repository and virtual labs b) using reflective thinking for andragogical and pedagogical Indian approach c) Indian teachers’ readiness to offer various genres of courses on demand d) reinforcing resilience in Indian schools through meaningful participation and conflict resolution e) purposeful learning and inquiry-based learning for Indian students f) experiential learning through an inclusive online pivot in India g) useful apps are discussed to reach out to Indian parents community. These initiatives can influence academicians, educationists, podcasters, and the entire teacher fraternity to design an efficient and adequate teaching plan for the student community in India.
Radiofrequency Thermoablation On Ex Vivo Animal Tissues: Changes on Isolated Swine Thyroids
Authors: Pregel Paola , Scala Elisa , Bullone Michela , Martano Marina , Nozza Linda , Garberoglio Sara , Garberoglio Roberto , Bollo Enrico , Scaglione Frine Eleonora
Published: June 2021

The use of Radiofrequency thermoablation (RFA) for treating large thyroid nodules is limited by the modest efficiency of the available systems in terms of volume of the ablation zones (AZs). This increases the risk of incomplete ablation of the nodule. Systems employing perfused electrodes have been developed to increase the volume of the AZ. Aim of this study is to compare the size of the AZ induced by RFA systems using internally cooled perfused vs. non-perfused electrodes in swine thyroids. RFAs were performed on 40 freshly isolated swine thyroids using both systems. The perfused system was tested using 0.9% saline, 7% and 18% hypertonic saline solutions. Energy delivery to the tissue was stopped when tissue conductivity dropped (real life simulations) and after an established time of 20 seconds (controlled duration). Following RFA, thyroids were transversally and longitudinally cut. Photographs were taken for macroscopic morphometry of the ablated zones before and after formalin fixation, to evaluate tissue shrinkage. Microscopic morphometry was performed on PAS stained sections. In real life simulation experiments, gross morphometry revealed that AZs produced with electrodes perfused using 7.0% saline are larger compared to isotonic saline. Microscopically, all the conditions tested using the perfused system produced larger AZs compared to non-perfused system after 20 seconds of RFA. In conclusion, the perfusion with 7.0% NaCl solution increased the electrical conductivity of the tissue in real life simulations, resulting in larger ablated areas compared to the use of isotonic saline.
Protective Mechanism of Humanin Against Oxidative Stress in Aging-Related Cardiovascular Diseases
Authors: Cai He , Liu Yunxia , Men Hongbo , Zheng Yang
Published: June 2021

Physiological reactive oxygen species (ROS) are important regulators of intercellular signal transduction. Oxidative and antioxidation systems maintain a dynamic balance under physiological conditions. Increases in ROS levels destroy the dynamic balance, leading to oxidative stress damage. Oxidative stress is involved in the pathogenesis of aging-related cardiovascular diseases (ACVD), such as atherosclerosis, myocardial infarction, and heart failure, by contributing to apoptosis, hypertrophy, and fibrosis. Oxidative phosphorylation in mitochondria is the main source of ROS. Increasing evidence demonstrates the relationship between ACVD and humanin (HN), an endogenous peptide encoded by mitochondrial DNA. HN protects cardiomyocytes, endothelial cells, and fibroblasts from oxidative stress, highlighting its protective role in atherosclerosis, ischemia–reperfusion injury, and heart failure. Herein, we reviewed the signaling pathways associated with the HN effects on redox signals, including Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2), chaperone-mediated autophagy (CMA), c-jun NH2 terminal kinase (JNK)/p38 mitogen-activated protein kinase (p38 MAPK), adenosine monophosphate-activated protein kinase (AMPK), and phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)-Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3). Furthermore, we discussed the relationship among HN, redox signaling pathways, and ACVD. Finally, we propose that HN may be a candidate drug for ACVD.
A Research Study to Increase Usage of PVs in Residential Areas
Authors: Kiray Vedat
Published: June 2021

Self-generation of energy by residential houses has been met with many obstacles. When PV Solar energy technology is considered, the barriers manifest in problems related to the location, slope, strength, and shade exposure of house roofs are the most common. Therefore, it is not possible to meet daily energy needs from PV panels placed on the existing roofs of many houses. Solar Tracking Systems keep PV panels perpendicular to the Sun throughout the day, providing a significant increase in their efficiency. But the application of these systems on the roofs or houses is not suitable for many reasons, especially in terms of aesthetic appearance. This article is aimed at effectively showing how the slope and direction inconsistencies in the existing roofs of houses in residential areas cause great losses in the performance of PVs; also a research and design study is presented to find a solution to the application of Sun tracking systems in residential areas without creating aesthetic appearance problem. As a solution, combining a dual axis Sun tracking system with an aesthetic looking Gazebo has been considered. A design study was carried out for the targeted system, and the dimensions of a movable platform/roof such a system should have in order to meet the electricity needs of a house from the Sun throughout the year was investigated. How much energy the PV panels can collect annually is determined by a simulation program called “PV performance tool”.