bluuebunny/crossref_metadata_2025 huggingface dataset:
An Evaluation of the Instructions in English Textbook for the Tenth-Grade Students of Senior High School
Authors: Farida Luthfia Nibrosi
Published: May 2023

The research aims to (1) explain whether the students can understand the English textbook instructions (2) explain the component of the English textbook instructions that affect the students’ unsuccess in understanding the textbook instructions (3) evaluate whether the English textbook instructions for the tenth grade of senior high school meet the criteria of Ur (1996) and Harmer (2007) theories. This research uses a descriptive qualitative research design, then the data collection techniques are observation, interview, and document analysis, the analysis begins with reading and studying all the data. Then continues by observing and interviewing the students and the English teacher. The result of this study showed that 38% of the students found themselves capable of understanding they were able to understand instructions in the textbook. The rest of the students still struggled in understanding the textbook instruction. Unfamiliar words are the most affecting the students’ unsuccess in understanding textbook instructions. The textbook instructions that exist in the textbook entitled “Bahasa Inggris untuk kelas X” is categorized as “very clear” and “very unambiguous” based on Ur (1996) and Harmer (2007) theories. The results of the analysis showed that students need teacher assistance in understanding textbook instructions even though the instructions are categorized as clear instructions.

Keywords: Textbook Analysis, Textbook Instructions, English Textbook
Conceptual Problems of Political Parties Cadre Management in the Reform Era in Indonesia
Authors: Joko Purnomo Girisusilohadi , Purwana Dedi , Anwar Choirul
Published: May 2023

This study describes the dynamics and practices of political party management in Indonesia after entering the reform era. The hopes for the welfare of the Indonesian people towards the existence of political parties in Indonesia have not shown significant results. Political parties are still trapped by internal interests compared to the big goal of improving the welfare of society, even the party's reputation in politics tends to decrease in society because of practices that violate the norms of decency. This study uses a qualitative method with a descriptive analysis approach
From the existing data, factual problems of political parties were found. The political party cadre system is unable to build cadre capacity, there is no capacity standardization in cadre recruitment, cadre capacity shifts to financial capacity, personal motivation is still unstable and always changes when cadres have occupied legislative positions and regional heads. The organizational climate of political parties is periodic, only before elections, there is no integrated teamwork in political parties, political work in political parties still depends on the interests of cadres. The leadership role in the lower regions is not able to translate the vision, mission and policy directives of the top level leaders, the top level leadership is unable to absorb aspirations and communication from the lower level leadership.
This research has a novelty that the management of political parties really needs the implementation of human capital. The human capital approach is currently still being applied to profit institutions and has never been tested in non-profit institutions, namely political party organizations.

Keywords: political parties, cadre governance, reformation era, human capital, leadership
The Relationship Between Platelet Lymphocyte Ratio (PLR) with Depressed Level in Patients with Chronic Kidney Disease (CKD) Undergoing Regular Hemodialysis at Haji Adam Malik General Hospital Medan
Authors: Lubis Wika Hanida
Published: May 2023

Background: Inflammation and stress levels associated with Chronic Kidney Disease (CKD) can lead to poor quality of life and adverse medical outcomes. Currently, the commonly used inflammatory tests in CKD patients are C-reactive protein (CRP), procalcitonin (PCT), and ferritin. Nonetheless, these tests have some drawbacks, such as being less specific, expensive, and difficult to access. Therefore, the platelet-lymphocyte ratio (PLR) can be considered as a promising alternative as a prognostic indicator in CKD patients with major depression.
Methods: This research is an analytical study with a cross-sectional design carried out in February 2023 until the number of samples is fulfilled, at the Hemodialysis Installation of RSUP. H. Adam Malik to analyze the relationship of PLR in depressed patients with CKD undergoing regular hemodialysis. The data analysis used is the Pearson correlation test if the data is normally distributed. If the data is not normally distributed, Spearman's correlation test is performed. Statistical analysis used a 95% confidence level (p<0.05).
Results: In this study, the demographic characteristics of 86 patients were obtained with a mean age of 49.08 years with a standard deviation of 14.11. Based on the Spearman rho test, it was found that there was no significant correlation between the PLR score and the BDI II score with a p value of 0.975. The r value is 0.003. This shows that there is a very weak correlation between the PLR score and the BD II score.
Conclusion: There is no correlation between Depression level and Platelet Lymphocyte Ratio (PLR) in CKD patients undergoing regular hemodialysis.

Keywords: Depression, Platelet Lymphocyte Ratio (PLR), chronic kidney disease (CKD), Inflammation
Saberes locais na construção dos conceitos sobre o solo: contribuição da etnopedologia.
Authors:   , Caetano do Nascimento Josilene
Published: May 2023

O presente trabalho aborda o solo, recurso básico que suporta toda a cobertura vegetal e exerce múltiplicas funções ecossistêmicas para o equilíbrio ambiental e a manutenção da vida no Planeta. A relação do ser humano com o solo remonta a própria história da Agricultura e é estudada pela Etnopedologia. A pesquisa, um estudo de caso, objetivou verificar a percepção dos agricultores familiares da Comunidade Rural Pitombeira, município de Sumé, Cariri paraibano, sobre o solo: qualidade, fertilidade, usos e práticas conservacionistas. A pesquisa foi dividida em duas etapas, a pesquisa bibliográfica e a pesquisa a campo. A pesquisa bibliográfica se constituiu na coleta dos referenciais para a fundamentação teórica. Foram coletados dados referentes ao tema junto à biblioteca e internet. Na pesquisa de campo foi realizado um estudo de caso, com levantamento de dados a partir da aplicação de questionários, que visa descrever as características dos agricultores suas opiniões, atitudes e visões sobre o solo. Os resultados indicam que os agricultores associam solo, qualidade e fertilidade do solo à produção agrícola e produtividade das culturas, evidenciam na percepção sobre a Caatinga a problemática climática que emerge do imaginário popular sobre o ambiente inóspito e não associam o recurso solo ao bioma Caatinga. O diálogo foi fundamental para entender a visão dos agricultores, auxiliando no processo de interação, de forma a permitir mais aproximação na condução da pesquisa. Considera-se que o saber Etnopedológico deve permear as atividades da construção do conhecimento agroecológico e da conservação do solo, promovendo a discussão sobre o saber empírico e o saber científico e que as metodologias participativas e dialógicas devem ser incentivadas nos trabalhos de diagnóstico e percepção, sobretudo quando se pretende diminuir os impactos aos recursos naturais e estimular a adoção de práticas conservacionistas.
Respostas aos agricultores: produtividade do feijão (vigna unguiculata brs pujante) em função de diferentes fontes de adubação orgânica.
Authors:   , Carvalho Silva Aline
Published: May 2023

Avalia o desenvolvimento da cultura de feijão (Vigna unguiculata BRS Pujante), utilizando diferentes fontes de adubação orgânica. Conduz um experimento, em delineamento inteiramente casualizado, com cinco tratamentos (composto, húmus, esterco caprino, mix dos adubos e o controle), em quatro repetições. Adota práticas culturais agroecológicas para o preparo inicial do solo e condução do experimento, e em seguida foi efetua a aplicação dos tratamentos, com antecedência de duas semanas da semeadura. Foram avaliados o número de vagem, número de grãos com e sem vagem, massa da matéria verde e seca. Os resultados mostraram efeito significativo das fontes de adubo orgânico sobre a testemunha, com maior expressão para o esterco caprino, que superou os demais em todas as variáveis analisadas. Conclui-se que, nas condições edafoclimáticas do experimento, a aplicação de diferentes fontes de adubação orgânica promoveu ganhos importantes na produtividade do feijoeiro irrigado por gotejamento, evidenciando a importância da matéria orgânica do solo para os agroecossistemas familiares.
Contextualizando a educação em solos com professores e estudantes de uma escola municipal.
Authors:   , de Carvalho Silva Luana
Published: May 2023

O solo é o recurso ambiental responsável por inúmeros serviços ecossistêmicos que sustentam a vida. Conhecer o solo é promover possibilidades de minimização dos processos erosivos que comprometem a vida em todas as suas manifestações, permitindo que este valioso recurso possa dar continuidade a multiplicidade de funções que exerce no equilíbrio ambiental. Considerando que a escola é espaço para ampliar a socialização de conhecimento sobre solos, que devem ser construídos desde as primeiras séries, a pesquisa objetivou compreender a percepção de alunos e professores em relação a esta temática. O estudo foi realizado numa escola municipal de ensino fundamental do município de Sumé (PB). A metodologia constou da aplicação de questionários com estudantes e professores, apresentação de palestras e realização de vivências. De forma geral, os estudantes associam solo à terra (69%), que o solo serve para plantar (38%), ligam a presença do solo a zona rural (11%), acham que queimar e desmatar fazem mal ao solo (19%). Já os professores apresentam uma visão holística do solo (39%), mas não trabalham o tema solo em sala (50%) e considera a abordagem do tema solo nos livros didáticos de regular a insuficiente (39%). A vivência trouxe muito interesse aos participantes. Concluí-se que é preciso, na perspectiva da Educação em Solos, para a formação cidadã, inserir a temática de forma mais expressiva nos conteúdos escolares, de forma inter e multidisciplinar, sobretudo, contextualizando com as especificidades dos diversos Territórios.
Avatars of Censorship and the Human Condition in a Post-utopian Society
Authors: Ivanov Constantin
Published: May 2023

The promotion of the scenario which fully covers the electricity demand from renewable sources leads to an electricity price increase, mostly impacting poor population from the Republic Moldova. In order to decrease the Absolute Poverty Rate, the paper proposes a way to determine the appropriate allowances. Achieving the objective is hampered by the fact that the existing Methodology for calculating the Absolute Poverty Threshold does not expressly contain the component related to the expenses for the electricity services provided. Such an algorithm is proposed in this regard using the structure of household consumption by categories of consumption, available at distribution companies. The calculations showed that the promotion of the concept of covering the power demand from renewable sources does not significantly harm the payment capacity of household consumers, in terms of the 2020-2021 years costs.
Ang Pagbebenta sa Imahen ng Kalalakihan sa mga Piling Tindahang Pandamit sa Pilipinas
Authors: Cañete Reuben
Published: May 2023

The concept of space as "neutral" has been critiqued in the contemporary period as a form of occlusion for other acts that are performed by its actors, the masses that populate this space. Among newer critical perspectives, space is an active location occupied by social and individual agency, resulting in the "multifunctionality" of this space. In the present context, Filipino public space is defined by urbanization as determined by capitalistic economic forces that interlink labor bodies and consumerist products within a comprehensive system of material and sexual exchange. This paper looks at the phenomena of "selling" the image of masculinity among selected clothing and fashion stores like Bench, Folded & Hung, and Penshoppe as a manifestation of the functionalization of consumer space as a potential location for the male body to become a product itself in the new market of globalization, the shopping mall. Utilizing the critical theory and political economy, the study analyzes the relations between material existence in the city during the age of globalization; the role that labor plays as both consumer and product; and the role that desire plays as an active mechanism in the development of the visual and sexual economy in the late period of capitalism. Another aim of this paper is to outline a theory of consumption that can be interrelated to Marx's theory of production, in order to produce a more comprehensive analysis of the effects of material existence in society, and in the lives of its people.
HOW FAMİLY PLANNİNG SERVİCES WERE AFFECTED DURİNG THE COVID-19 PANDEMİC?
Authors: KARAKAŞ Sevda , KURU AKTÜRK Nur Bahar , İŞBAY Beyzanur
Published: May 2023

This study was planned to determine how family planning services were affected during the COVID-19 pandemic. Our descriptive study was carried out at the Gynecology and Pediatrics Training and Research Hospital in Istanbul.The study population consisted of sexually active women aged 18-40 who applied to the hospital between January and March 2022 and volunteered to participate in the study.As a result of the power analysis in determining the study sample, the sample size was determined as 390 women.The data used in the study were collected through face-to-face interviews. In our study,it was found that 79.5% of sexually active women with a mean age of 30.78±5.7 years could not receive FP services during the COVID-19 pandemic, one out of every five women had difficulty accessing modern contraceptive materials, and one out of every four unintended pregnancies resulted in abortion.It was determined that due to the COVID-19, 72.8% of women could not get FP service because they had problems accessing the health institution,80.3% could not get FP services because health institutions were dense,87.9% could not get FP service because they could not get an appointment from health institutions and 25% could not get FP service because they were afraid of the risk of the COVID-19 transmission in health institutions. The critical purpose of FP services in community-based nursing services is to prevent unintended pregnancies and ensure safe motherhood.Our study's high rate of inaccessibility (79.5%) to AP services proves that FP services are interrupted during the COVID-19 period.
Evaluation of Consumers' Perceptions and Purchase Decisions Regarding Plant-Based Milk Alternatives in Turkey
Authors: ÇAKIR BİÇER Nihan , BAŞ Dilşat , SEÇKİNER Selda , KAHRIMAN Meryem , BAŞ Murat
Published: May 2023

In the global world, plant-based milk alternatives have taken an important place in the food industry and have attracted great interest from consumers. This study was conducted to determine the main reasons why individuals prefer plant-based milk alternatives and the driving factors affecting their purchasing behavior towards plant-based milk alternatives. For this purpose, the sociodemographic characteristics, and general nutritional habits of 895 participants were questioned. In addition, the status of consuming plant-based milk alternatives of the participants in the last year was questioned and the purchasing decisions of the participants who reported that they consume these products and the factors that drive them to buy these products were evaluated. 796 women (88.9%) and 99 men (11.1%) participated in the study. The mean age of the participants is 31.17±9.62. Most of the participants (36.4% of women and 72.7% of men) reported that they never consumed plant-based milk alternatives. The most consumed plant-based milk alternatives were determined as almond milk (80.9%), coconut milk (60.2%), and soy milk (51.2%). The most frequent reason why consumers choose plant-based milk alternatives is determined as "Non-dairy milk contains good fat". The participants reported that dieticians have the most influence on their choices (x̄=3.35±1.27) and these products were mostly purchased from supermarkets and online channels. In addition, considering that drinking plant-based milk is beneficial for health (OR=1.978) and exercising regularly (OR=1.337) increases the odds of being a regular consumer. In conclusion, it is determined that consumer acceptance of plant-based milk alternatives is affected by the consumer's perception of healthy food, marketing strategies, and consumer expectations.
Quantifying the Impact of Dysmenorrhea Symptoms on Quality-of-Life and Access to Oral Contraceptives by Income
Authors: Choksey Rhea , Mangal Rohan K. , Stead Thor S. , Jones Terrika , Flores Rosa , Ganti Latha
Published: May 2023

Background

Dysmenorrhea, or painful menstrual periods, is one of the most common gynecological complaints. Most reports of uterine contractions range between moderate to severe pain, and patients often elect to cope with their discomfort without assistance from a physician. In the process, women experiencing dysmenorrhea are more likely to report absenteeism from work and school.

Objectives

This study measures the reported impact of dysmenorrhea on patients’ lives and elucidates a relationship between income and access to oral contraceptives.

Methods

Two hundred women completed a survey about their symptoms, level of pain, treatments, and the extent to which dysmenorrhea affected day-to-day obligations. Most questions were multiple-choice while others permitted several answer selections or were free response. The data was analyzed using JMP statistical software.

Results

Eighty-four percent of respondents reported moderate to severe pain during menstruation. This discomfort has caused 65.5% of the cohort to miss work and 68% to avoid participating in social gatherings. Pain relief medications are most often used as treatment - 143 respondents took ibuprofen, 93 took acetaminophen, and 51 took naproxen. 29.5% of respondents are prescribed birth control for cramps and blood flow. Income (p = 0.049), age (p = 0.002), and education (p = 0.002) were significant predictors for oral contraceptive pill (OCP) use. The lowest income groups were found to use OCPs at less than half the rate as the highest income respondents.

Conclusion

Dysmenorrhea affected most participants in the cohort with an impact that extends beyond professional obligations. Income was found to be positively correlated with increased OCP use, whereas education level was inversely correlated. Clinicians should consider how patients’ backgrounds influence their access to OCP options. An improvement on this study’s findings would be to establish a causal relationship between these demographic factors and access to OCPs.
A STUDY OF SOCIO-POLITICAL ISSUES TRIGGERING INSTABILITY AND FAILURE OF STATE IN NOBODY KILLED HER
Authors: Farooq Athar , Ahmed Abrar , Ahmed Mustanir
Published: May 2023

Pakistan’s history is evidence of the fact that it has failed to achieve stability and growth since its founding. Political instability started in the early years and continues to this day thereby leaving the state institutions crippled and inefficient. The political and economic problems have also weakened the state’s writ and the combination of these varied factors has pushed the state towards failure. This research studies novel, Nobody Killed Her, to analyze the state failure in the novel. The characters in the novel suffer because of the lawlessness of the state and not given their fundamental human rights. Qualitative content analysis technique is used to carry out this research. The study comes to conclusion that state responsibilities are not fully executed by the government institution in the selected novel. The results of study offer significant information in reaching the conclusion and making the desired and leading decisions about phenomena. It further establishes link between hybrid regimes and failed states, as well as the dire predicament that failed states place their population.
Elementos kantianos na filosofia da matemática de Ernst Cassirer
Authors: Amaral Lucas Alessandro Duarte
Published: May 2023

A tarefa deste artigo é explicitar algumas influências kantianas na filosofia da matemática do neokantiano da escola de Marburgo, Ernst Cassirer. Conforme argumentamos, em sua primeira obra sistemática, Conceito de Substância Conceito de Função: uma investigação sobre as questões fundamentais da Crítica do Conhecimento (1910), certos pressupostos da filosofia transcendental de Kant (tais quais, e.g., seu compromisso anti-metafísico manifesto e sua ideia de “lógica transcendental”) desempenharam papéis importantes na filosofia da matemática de Cassirer, servindo enquanto conceitos complementares ao logicismo-estrutural defendido pelo neokantiano.
O conceito de técnica na pedagogia social de Paul Natorp
Authors: Braga Joaquim
Published: May 2023

Para fazer da pedagogia social uma verdadeira alternativa ao psicologismo dominante nas teorias educativas do seu tempo, Paul Natorp apoia a sua abordagem conceptual em três eixos capitais, a saber: a vontade, a comunidade e a autodeterminação. É, contudo, o conceito de técnica que propriamente estabelece as condições de ligação entre esses eixos e, por sua vez, lhes dá um sentido pedagógico alargado a todas as esferas da sociedade em que a questão da formação dos indivíduos é mais visível e necessária. Sendo intimamente associada ao conceito de trabalho, a visão natorpiana da técnica confere à própria pedagogia social um estatuto tecnológico que, como se verá, adquire um poder vigilante sobre todos os outros domínios em que há mediação técnica. Atendendo a esta sua dupla implicação, intentarei mostrar como a técnica, na teoria d Natorp, se funda numa visão tecnocêntrica das relações e instituições sociais, assim como das capacidades racionais atribuídas aos indivíduos.
Empirical Study on the Impact of Environmental Uncertainty on Dynamic Adjustment of Financial Flexibility
Authors: Li Xingyue
Published: May 2023

From the perspective of environmental uncertainty, this paper further studies whether the dynamic adjustment of the financial flexibility of enterprises will be affected by environmental uncertainty and its changes. Through the research, it is found that there is a reasonable level of target flexibility, and the actual financial flexibility of enterprises will constantly converge to the target. Environmental uncertainty will accelerate the dynamic adjustment of financial flexibility. The change in environmental uncertainty will also accelerate the dynamic adjustment speed of financial flexibility. It can help enterprises correctly understand financial flexibility, and then guide enterprises to make reasonable and effective financial decisions so that the financial decisions of enterprises are more scientific.
Apreciación de espacios públicos de esparcimiento: un recurso de medición de la infraestructura en la ciudad
Authors: Gómez-Vera Laura Teresa , Retana Olvera Juan Luis
Published: May 2023

El diseño de proyectos urbanos ha tenido un auge importante no sólo por su identificación en la ciudad des­de sus formas, sino como un conjunto en sí mismo entre los elementos funcionales que la integran y conforman su esencia. El propósito del presente trabajo es ex­poner macro indicadores para medir el desempeño de los es­pacios públicos abiertos y cerrados de esparci­miento en las ciudades, así como las condiciones de conectividad que presentan. Se muestran las categorías de inclusión y pertenencia a fin de medir estos atributos en la población usuaria. Desde esa lógica se desprenden diez ma­cro indicadores de tipo cuantitativo, que a su vez dan lugar a 180 sub-indicadores. Además se incluye un mo­delo que induce a la conformación de un indicador glo­bal. Las aportaciones de este estudio se reflejan en la diferenciación que estas categorías tienen con respec­to a los estudios de diseño urbano para intervenir en la gestión y planeación de políticas que respondan a los lineamientos del derecho a la ciudad.
Provenance variation in growth characteristics of Acacia catechu Willd. in Himachal Pradesh, India
Authors: Lekha Chander , Sharma Kulwant
Published: May 2023

The present study was conducted in the provenance trail of Acacia catechu raised at Regional Horticulture Research Station, Jachh, Himachal Pradesh, India (32o18’N and 75o55’E, 428 m above mean sea level alt., 1000-1250 mm rainfall. Significant variations (P<0.05) were observed for height, diameter (DBH), sapwood, heartwood percentage and above ground biomass among the provenances. Wide ranges in the means were exhibited by height (6.76 m to 9.74 m), DBH (10.20 cm to 15.25 cm), sapwood (41.60-67.72%), heartwood (21.13-47.91%), above ground biomass (20.20 kg to 54.49 kg per tree) of tress. The highly significant and positive correlation (0.6632) was found between diameter and above ground biomass of trees. The highly significant and negative correlation (-0.9752) was recorded between heartwood and sapwood percentage. The heritability estimates (98%) were highest for height and lowest (13.1%) for bark percentage. The genetic gain and genetic advance were the highest (42.81%, 24.31%) for sapwood and least (4.82%, 0.46%) for bark percentage. The genotypic and phenotypic coefficient of variation ranged from 6.19% to 23.89%, and 6.43% to 34.54%, respectively for different parameters. The variations are useful for breeding work on this important multipurpose tree of subtropical regions.
הוראת STEM ולמידת STEM בבתי ספר – הגדרות, מטרות ודרכי ההערכה והשלכותיהן לגבי הכשרת מורים
Authors: שטיינברג שרון
Published: May 2023

בספרות המחקרית אין הגדרה אחידה להמשגה של המונח 'STEM'. ראשי התיבות 'STEM' מייצגים את הכינויים באנגלית של מדעים (פיזיקה, כימיה, ביולוגיה), טכנולוגיה, הנדסה ומתמטיקה. הספרות כוללת מגוון של שימושים במונח STEM. לפני שנת 2000 המונח התייחס לדיסציפלינות הנפרדות – שם נרדף למדעים. מחקרים התמקדו בצורך לשפר הצלחות במקצועות אלה, כמעט ללא שילוב של הנדסה וטכנולוגיה. גם בשני העשורים האחרונים יש המשתמשים במונח כתחליף למושג 'מדעים', לתיאור תחום דעת אחד מבין התחומים: כימיה, פיזיקה, ביולוגיה ומתמטיקה. ישנה מחלוקת לגבי מספר מקצועות ה־STEM וסוגם החייבים להיות משולבים יחד. לפי חלק מההגדרות, שילוב של שניים או שלושה מהמקצועות המרכיבים את המונח STEM ייחשב לחינוך STEM, ואילו על פי גישה אחרת חייבים לשלב יחד רכיבים של הנדסה, טכנולוגיה, מתמטיקה ולפחות מקצוע מדעי אחד. אולם, קיימת ביקורת שההתמקדות במספר תחומי הדעת ובשאלה אילו תחומים יש לשלב, מגבילה מדי וחשוב יותר להתמקד בפרקטיקות ובתהליכי חציית גבולות של תחומי הדעת. מסיבה זאת יש הכוללים בנוסף לתחומי הדעת המקוריים, גם תחומים נוספים, למשל, מפסיכולוגיה וממדעי החברה, כגון כלכלה או פוליטיקה וממשל או מחשבים ומדעי הנתונים או רפואה. לפעמים מוסיפים אות לראשי התיבות, למשל לתיאור התחום הנוסף. מאמר זה מתמקד במונח המקורי הרווח STEM, אך העקרונות רלוונטיים גם לתוספות של תחומי דעת. המונח STEM תכלולי (אינטגרטיבי) מתאר הוראה שחוצה תחומי דעת שונים ומשלבת ביניהם.
Mecanismo bioquímico de los cánceres: Una revisión del linfoma
Authors: Hernández Centeno David , Sigarán García Camila , Madrigal Solano Tatiana , García Madrigal Mareling
Published: May 2023

Entre los tipos de cáncer que afectan el sistema inmune, está el linfoma caracterizado por ser un conjunto heterogéneo de neoplasias hematológicas de los tejidos linfoides, originando en diferentes progenitores de las células B, células T y células NK. Representan uno de los tipos de cáncer más comunes y poseen una alta tasa de mortalidad. Se clasifica en dos grupos principales, el linfoma de Hodgkin y el linfoma no Hodgkin. Estas células cancerígenas llevan a cabo una reprogramación metabólica aberrante que les permite abastecerse de macromoléculas y metabolitos necesarios para su proliferación, asimismo cuentan con mutaciones en distintas vías de señalización química como aquellas mediadas por citoquinas – JAK/STAT, del factor nuclear kappa-B – y la PI3K/Akt/mTOR, permitiendo regular procesos de la progresión cancerígena. El sistema inmune cuenta con la capacidad de detectar y eliminar células malignas, pero se ha observado que esta enfermedad cuenta con mecanismos y estrategias que permiten erradicar la respuesta inmunitaria y ser resistentes a su regulación mediada por muerte celular y otros procesos moleculares. No obstante, estudios de la biología del cáncer y el desarrollo de novedosos métodos para el diagnóstico y terapia han impactado positivamente en la prevención y control de este tipo de enfermedad.
Síndrome de Ovario Poliquístico: Actualización en diagnóstico y tratamiento
Authors: Barquero Gen Meylin Cecilia , Bitter Rosales Maressa
Published: May 2023

El Síndrome de Ovario Poliquístico es un conjunto de manifestaciones clínicas que poseen un diverso origen fisiopatológico, por ende, también posee floridas manifestaciones clínicas en las pacientes que lo padecen, esto origina que el diagnostico de esta patología sea una tarea complicada, y que el tratamiento de este sea sumamente individualizado respecto a las manifestaciones clínicas que posee cada paciente. Durante los últimos años se han propuesto distintos métodos de diagnóstico, sin embargo, los criterios de Rotterdam son los más utilizados y aplicando estos criterios se reconocen 4 distintos tipos de fenotipos de SOP. Respecto al tratamiento también se han planteado distintos manejos sobre esta patología incluyendo los cambios en el estilo de vida y el uso de anti androgénicos, para poder tratar el hirsutismo y el acné presentes en las pacientes. Sin embargo, uno de los aspectos más importantes a la hora de enfocar el tratamiento es el deseo de paridad de la paciente en cuestión. A lo largo de esta revisión bibliográfica se especificarán las distintas actualizaciones en diagnóstico y tratamiento, así como una propuesta de un algoritmo de manejo.
The Impact of the Establishment of a Unified National Market on the New Material Industry
Authors: Liu Yang , Ge Qiuying , Xu Quan , Hei Yihao
Published: May 2023

Since the reform and opening up policy in 1978, China's economic growth has brought an irreplaceable miracle to the world. In the past year, with a huge increase in international uncertainties, China has proposed the idea of building a unified national market, which is the fundamental support and inherent requirement for China to build a new development pattern in the new era. This article will be focusing on Bengbu City, Anhui Province, analyzing the current situation of the new material industry in Bengbu, analyzing the existing problems, and finally proposing relevant opinions to provide effective suggestions for the construction of a unified national market.
Research on Innovative Dynamic Allocation of Human Resources for University Teachers
Authors: Yuan Kunming
Published: May 2023

The research on the human resource management mode of university teachers has great practical significance, and innovating the human resource management mode of university teachers has increasingly become the core of internal management in universities. The dynamic allocation of human resources for university teachers covers basic content such as planning, recruitment, training, and development. The four parts together constitute the management module of resource dynamic allocation. The core to solving the allocation imbalance is to expect a quantifiable proportion of teachers, and to maximize the role of each individual is the ultimate goal of the dynamic allocation of human resources for university teachers. Among the influencing factors of the dynamic allocation of human resources for university teachers, external factors include the socio-economic environment and ideological environment, while internal factors mainly include the proportion of teachers, the ratio of students to teachers, the proportion of senior professional titles, the proportion of doctoral students, and the proportion of full-time teachers. The recruitment, training development, and development positioning of universities should have strategic operational norms, and the three aspects should be practical and feasible in university practice.
Winston’s Redemption in Orwell’s Nineteen Eighty-Four
Authors: Zhou Zhenni , Zhong Jingdong
Published: May 2023

Nineteen Eighty-Four is a political satire against the totalitarian government by the famous British writer George Orwell, one of the “Anti-Utopia Trilogy.” It depicts the destruction of Winston’s personality under the violence of war, lies, government surveillance, and physical restraint, and satirizes the dark and fearful totalitarian government. This paper will briefly elaborate on the previous studies on the novel. Then, the paper will explore Winston’s attempts at various forms of redemption in a society, resisting totalitarian oppression and ideological control. The far-reaching social and political significance of his redemptive acts will also be discussed.
Obstacle Analysis of Photovoltaic Building Rural Promotion
Authors: Zhang Chenyu
Published: May 2023

Photovoltaic buildings are promoted and developed in rural areas in the form of new, efficient and low-carbon clean energy utilization, which is an effective way to achieve the goal of " double carbon. " This chapter first introduces the concept and characteristics of photovoltaic buildings, and then analyzes the obstacles existing in the popularization and application of photovoltaic buildings in rural areas. They are: insufficient government support and tendentiousness, insufficient economic incentive policies, photovoltaic building-related enterprises. There is no upstream and downstream industrial chain, small scale of construction and interest-driven in rural areas, rural residents are bound by traditional concepts and lack of understanding of photovoltaic buildings. Finally, the countermeasures and suggestions for the promotion of photovoltaic buildings in rural areas are put forward from the perspectives of government, enterprises and rural residents.
The Application of Exercises in English Classroom Teaching based on the Concept of New English Curriculum Standard
Authors: Dai Caihong
Published: May 2023

Practice is a crucial link in classroom teaching. How to improve students' practice is an important problem that teachers should pay attention to in teaching. This paper mainly studies the application of practice teaching in the classroom, is a essential part of the language teaching practice, and the paper research mainly from contact with listening, speaking, reading, writing and translating a few aspects, analysis of English practice should pay attention to some problems, as well as the students how to use the classroom practice, promote efficiency of learning and learning interest problem is analyzed.
Research on Precision Advertising Push Method based on Neural Network
Authors: Qi Sheng , Long Yanbin
Published: May 2023

This project relates to an accurate advertising push method based on neural network, which belongs to the field of advertising technology.The method comprises the following steps: obtaining the sample vectors of each sample of potential users corresponding to the target advertisement;The sample vector is used to train the depth Q network, and the target depth Q network corresponding to the trained target advertisement is obtained;Obtain the target vector of each potential user corresponding to the target advertisement;According to the target vector and target depth Q network of potential users corresponding to the target advertisement, the target potential users to be pushed by the target advertisement at the next push time are obtained.This project can reduce the advertising expenses of enterprises, and also make the effect of enterprise advertising push better.
Study on the Prediction of Runoff Usability in Kaihua County
Authors: Cao Guangtian , Sun Jie
Published: May 2023

Small hydropower is an important infrastructure for people's livelihoods and clean renewable energy, but there are still many weak links in the planning, design, construction, operation, and management of small hydropower in some regions. Kaihua County is located at the source of the Qianjiang River, and the rational development and utilization of its water resources are of great significance for protecting the water ecological environment at the source of the Qianjiang River and achieving the development strategy goal of "ecological county and characteristic county" in Kaihua County. To alleviate the water reduction caused by the development and utilization of watershed hydropower and rural hydropower interception and diversion, and further provide data support for the assessment of small hydropower cleaning and rectification in Kaihua County, At the same time, it also provides data basis for the ecological flow management of small hydropower discharge. This article conducted a study on the available amount of runoff in Kaihua County. This article uses the ANFIS model to predict the runoff at Misai Station in Kaihua County. The simulation and prediction relative errors of this model can meet the error requirements, and this model can be applied to predict the runoff at Misai Station in Kaihua County. Using the simulated model for prediction, the runoff depth of Misai Station in Kaihua County in 2022 is approximately 2450.420. In 2023, the runoff depth of Misai Station in Kaihua County is approximately 2146. In 2024, the runoff depth of Misai Station in Kaihua County is approximately 771.16. The predicted results can provide a reference basis for the development of hydropower resources in Kaihua County and the regulation of discharge flow of the hydropower station in Kaihua County.
Clinical Efficacy of VSD in the Treatment of Orthopedic Trauma and Infected Wounds
Authors: Ding Guorui
Published: May 2023

Objective: To study the clinical effects of negative pressure closed drainage (VSD) in the treatment of orthopedic trauma as well as infected trauma. Methods: Fifty patients with orthopedic trauma and infected wounds admitted to hospital from March 2017 to May 2019 were selected and randomly grouped, and the various clinical effects of the two groups were compared. Results: All clinical effects of patients in the observation group were better than those in the control group (P < 0.05). Conclusion: The treatment of orthopedic trauma and infected trauma patients by VSD technology can improve the clinical effect and is worth promoting.
An Exploration of Strategies for Continuation Writing Teaching in High School
Authors: Xu Qingfang
Published: May 2023

With the deepening reform of education and the proposition of key competence, many disciplines have carried out reforms to improve students' key competence. In order to improve students' reading ability, thinking ability, writing ability and many other qualities, senior high school English has added a new form in the English exam, continuation writing, so that students can complete the subsequent writing practice on the basis of reading. Writing, as an important and foundational language competency, has always been a very important part of the training at every stage of English learning. Reading is the foundation of writing, and continuation writing is an effective way to train students. Continuation writing is a comprehensive examination of students' English literacy. In traditional writing, there are many problems such as teachers' insufficient attention and students' weak motivation, which make students fail to achieve good results in the process of writing. Based on the problems faced in the teaching of writing and the actual English teaching classroom, this paper puts forward some strategies to help teachers improve the teaching effect of continuation writing.
A Phosphorous-based Polyol for Flame Retarded Rigid Polyurethane Foam
Authors: Zhang Xiaoai , Xie Yichao , Guo Weiping , Yan Li
Published: May 2023

A phosphorus-containing polyol (P-polyol) was synthesized with diethyl ethylphosphate (DEEP) and trihydroxymethyl phosphane oxide (THPO) via transesterification reaction, which was introduced into rigid polyurethane foam (RPUF) by in-situ chemical reaction. The optimum synthesis conditions of P-polyol were investigated as follows: butyldihydroxychlorostannane as catalytic agent, the molar ratio of DEEP to THPO was 1:1 at 120-170℃, the yield was over 85%, the apparent viscosity of P-polyol was 1400 MPa.S with the hydroxyl value about 480 mg KOH/g  and the acid value about 100 mg KOH/g. With the increase of adding P-polyol, the flame retardant properties of the RPUF increased continuously. When the P-polyol amount in white material was 40%, the LOI reached24.7% and vertical combustion test rated UL 94 V-0. TGA results show that the P-polyol promotes the degradation and the formation of char residue of RPUF significantly. The polyurethane foam had the characteristics of condensation phase. Simultaneously, the compressive strength of RPUF was increased by 50 % and 21% in horizontal and vertical direction, respectively, compared with neat RPUF.
Structure and properties of the films based on ternary transition metal borides: theory and experiment
Authors: Onoprienko A. A. , Ivashchenko V. I. , Shevchenko V. I.
Published: May 2023

The review presents the results of theoretical and experimental studies of the structure, bonding between atoms, mechanical properties, thermal stability, and oxidation and corrosion resistance of films based on ternary transition metal borides.
The Just-About-Right Pilot Sample Size to Control the Error Margin
Authors: Obodo Scholastica C. , Toher Deirdre , White Paul
Published: May 2023

In practice, the required sample size for a two-arm randomised controlled trial cannot always be determined pre-study with great accuracy. This lack of accuracy has economic, ethical and scientific implications. The sample size for a pilot study is an important consideration in helping the decision making for the sample size of a follow-on trial. Consideration of under- and over-estimation of the sample size results in the idea of a Just-About-Right (JAR) sample size. For studies involving a minimally clinical important difference (MCID) we present the pilot sample sizes to meet investigator desired JAR considerations.
On the Separate Assessment of Structural Effects on the Simple Beam Deflection in the Light of Fractional Calculus
Authors: Lustosa J. I. S. , Bannwart F. C. , Oliveira E. C.
Published: May 2023

Euler-Bernoulli (EB) and Timoshenko-Ehrenfest (TE) theories model simple beams under linear constraints. But even keeping these constraints, specific structural effects in real applications compromise the accuracy of the models, such as stress concentration due to force reactions on the support contacts or bucking, for example. Both EB and TE solutions assume planar cross sections and structural stability, and therefore do not address those particular effects; the interest in using them is to explore the conditions under which shear effects are significant or not. Numerical solutions such as the ones obtained from the Finite Element Method (FEM) reach structural effects quite well, depending on the complexity of the problem and degree of refinement. However, although accurate, the numerical solutions do not distinguish whethera particular effect is on charge or not; they implicitly encompass all of them as a whole. To diagnose them for simple beams, analytical solutions such as EB or TE can be employed as long as they noticeably differ from the corresponding affected structures modeled in a FEM environment, the latter taken as reference. To measure this disagreement one can either directly compare each resulting deflection profile or, alternatively, compare the analytical solutions EB or TE against the corresponding fractional calculus ones fed with theFEM data. The second case, focus of this study, provides a better measurement, to our understanding, as the fractional order informs the magnitude of the effect not depending on absolute values, which allows a fairer evaluation. Each structure effect must be isolated so that to obtain the individually consequent order deviation from the original integer value. A separate assessment using fractional calculus is proposed in this work to, first, evaluate the effects of stress concentration on the support contacts, and, second, to preparethe modeling to potentially reveal another structural effect. Consistent results have been achieved.
Synchronization of the Circadian Rhythms with Memory: A Simple Fractional-Order Dynamical Model Based on Tow Coupled Oscillators
Authors: De Cezaro F. Travessini , Glaeaser S. S. , De Cezaro A.
Published: May 2023

Disruptions of the circadian rhythm are associated with internal desynchronization. It affects some internal functions of our body and behavior that are important to our health. Our modern lifestyle has contributed to millions of people developing some circadian rhythm disruptions, making the subject very important clinically as well as economically. Motivated by studying a simple mathematical model that can reveal some features of internal synchronization desynchronization, in this contribution, we extend the coupling oscillator phase model proposed by Strogatz [14] in the sense that memory is considered in the modeling. Such memory is a result of the introduction of Caputo-type fractional derivatives in the coupling oscillators’ phase model dynamics, resulting in a fractional phase model. We show that the proposed fractional coupling oscillator phase model is well-posed. Furthermore, we analyzethe synchronization phenomena. We obtain the synchronized solutions explicitly when the memory is equally distributed between the oscillators. In contrast, when distinct levels of memory are imposed in the modeling, we obtain lower and upper bounds because any existing synchronized solution must be confined in between. We present numerical realizations that support the theoretical findings in great detail.
Perancangan Ulang UI/UX Mika dengan Metode Design Thinking
Authors: Felix Felix , Pipin Sio Jurnalis , David David , Al-Mawaddah Thiyara
Published: May 2023

Mika adalah portal akademik yang digunakan oleh Universitas Mikroskil untuk mengakamodasi kebutuhan-kebutuhan yang berkaitan dengan data akademik. Pengguna Mika berasal dari berbagai kelompok seperti mahasiswa, dosen, dosen penasihat akademik, BAA, Prodi, hingga pihak Wakil Rektor I. Sebagai salah satu website penting bagi warga kampus Mikroskil, Mika masih dapat dikembangkan dengan lebih baik lagi untuk menghasilkan UI/UX yang sesuai dengan kebutuhan pengguna. Pengembangan Mika sampai sekarang masih menggunakan teknik-teknik yang belum berorientasi kepada pengguna sehingga belum mencapai potensi yang maksimum. Design Thinking hadir sebagai suatu pendekatan yang mampu memberikan solusi yang lebih baik. Hal ini dikarenakan metode ini berpusat kepada pengguna sehingga kebutuhannya dapat terpenuhi meskipun pengguna sendiri bisa saja belum tahu pasti apa masalah yang dihadapinya. Masalah demikian dikenal dengan istilah ill-defined problem dan wicked problem. Design Thinking terdiri dari 7 tahapan yaitu: Understand, Observe, Define point of view, Ideate, Prototype, Test, dan Reflect. Setiap tahapan dapat dikerjakan dengan beragam tool yang ada sesuai dengan kebutuhan dan kondisi. Tool-tool tersebut juga dapat digunakan secara seri maupun paralel. Hasil penelitian ini diharapkan mampu menghasilkan sebuah rancangan UI/UX Mika yang lebih sesuai dengan kebutuhan pengguna sehingga dapat memaksimalkan potensi website tersebut.