bluuebunny/crossref_metadata_2025 huggingface dataset:
Grid Refinement in ICON v2.6.4
Authors: Zängl Günther , Reinert Daniel , Prill Florian
Published: May 2022

Abstract. This article describes the implementation of grid refinement in the ICOsahedral Nonhydrostatic (ICON) modeling system. It basically follows the classical two-way-nesting approach known from widely used mesoscale models like MM5 or WRF, but differs in the way how feedback from fine grids to coarser grids is applied. Moreover, the ICON implementation supports vertical nesting in the sense that the upper boundary of a nested domain may be lower than that of its parent domain. Compared to the well-established implementations on quadrilateral grids, new methods had to be developed for interpolating the lateral boundary conditions from the parent domain to the child domain(s). These are based on radial basis functions (RBFs) and partly apply direct reconstruction of the prognostic variables at the required grid points, whereas gradient-based extrapolation from parent to child grid points is used in other cases. The technical implementation on the unstructured ICON grid is based upon sorting the boundary interpolation points at the beginning of the grid-point index vector, so that computations on boundary interpolation points can be excluded by appropriate start indices without the need of IF masks. The run-time flow control is written such that limited-area domains can be processed identically to nested domains except for the lateral boundary data supply. To demonstrate the functionality and quality of the grid nesting in ICON, idealized tests based on the Schär mountain wave test case (Schär et al., 2002) and the Jablonowski-Williamson test case (Jablonowski and Williamson, 2006) are presented. The results show that the numerical disturbances induced at the nest boundaries are small enough to be negligible for real applications. This is confirmed by experiments closely following the configuration used for operational numerical weather prediction at DWD, which demonstrate that a regional refinement over Europe has a significant positive impact on the forecast quality in the northern hemisphere.
Hydrometeorological evaluation of two nowcasting systems for Mediterranean heavy precipitation events with operational considerations
Authors: Lovat Alexane , Vincendon Béatrice , Ducrocq Véronique
Published: May 2022

Abstract. Heavy precipitation events and subsequent flash floods regularly affect the Mediterranean coastal regions. In these situations, forecasting rainfall and river discharges is crucial especially up to 6 h, which is a relevant lead time for emergency services in times of crisis. The present study investigates the hydrometeorological skills of two new nowcasting systems: a numerical weather model AROME-NWC and a nowcasting system blending numerical weather prediction and extrapolation of radar estimation called PIAF. Their performance is assessed for 10 past heavy precipitation events that occurred in southeastern France. Precipitation forecasts are evaluated at a 15- min time resolution and the availability times of forecasts, based on the operational Météo-France suites, are taken into account when performing the evaluation. Rainfall observations and forecasts were first compared using a point-to-point approach. Then the evaluation was conducted from an hydrological point of view, by comparing observed and forecast precipitation over watersheds affected by floods. In general, the results led to the same conclusions for both evaluations. On the very first lead times, up to 1 h 15 min and 1 h 30 min of forecast, the performance of PIAF was higher than AROME-NWC. For longer lead times (up to 3 h) their performances were generally equivalent. An assessment of river discharges simulated with the ISBA-TOP coupled system, which is dedicated to Mediterranean flash flood simulations and driven by AROME-NWC and PIAF rainfall forecasts, was also performed on two exceptional past flash flood events. The results obtained for these two events show that using AROME-NWC or PIAF rainfall forecasts is promising for flash flood forecasting in terms of peak intensity, timing, and first wave of discharge, with an anticipation of these phenomena that can reach several hours.
High-Reynolds-number investigations on the ability of the full-scale e-TellTale sensor to detect flow separation on a wind turbine blade section
Authors: Soulier Antoine , Braud Caroline , Voisin Dimitri , Danbon Frédéric
Published: May 2022

Abstract. The complexity of the flow over a wind turbine blade makes its understanding and monitoring a challenging task, especially on operating wind turbines. The innovative electronic TellTale (e-TellTale) sensor is developed for that purpose – detecting the flow separation on wind turbines blades. In this paper, high-Reynolds-number wind tunnel tests have been performed with different configurations of full-scale e-TellTale sensors and wall pressure measurements on a wind turbine blade section. A comparison between the lift curve and the e-TellTale signal was used to evaluate the ability of the sensor to detect flow separation. Results show different interesting properties of the sensor response depending on its size, position along the chord and fitting process that could be used in real applications.
Escritoras romanas para la educación literaria en Latín II
Authors: San Juan Manso Enara
Published: May 2022

Aunque la literatura fue en Roma una actividad prácticamente exclusiva de los hombres, también algunas mujeres romanas llegaron a expresarse mediante la palabra escrita. De esas escritoras únicamente conservamos textos aislados o fragmentos, que no suelen ser objeto de atención de antologías y manuales de literatura latina. En este trabajo analizamos el modo en el que el currículo de Latín II de 2.º de Bachillerato orienta el estudio de la literatura y hacemos una propuesta para contribuir a la educación literaria mediante la inclusión de textos de esas mujeres en la asignatura.
Ana Peñas Ruiz (ed.) (2021). Literatura y ELE: miradas desde los estudios literarios y culturales. Madrid: Enclave-ELE y UDIMA. 330 pp.
Authors: Albaladejo García María Dolores
Published: May 2022

Reseña de la obra de Ana Peñas Ruiz (ed.) (2021). Literatura y ELE: miradas desde los estudios literarios y culturales. Madrid: Enclave-ELE y UDIMA. 330 pp.
La interferencia de la L1 inglés en la producción escrita de ELE: estudio basado en un corpus informatizado de aprendices
Authors: Núñez Nogueroles Eugenia Esperanza , Ruiz-Cecilia Raúl
Published: May 2022

Este trabajo explora la interferencia que la lengua materna (inglés) ejerce en la producción escrita en la lengua meta (español). Para ello, se han examinado 50 textos creados por estudiantes de ELE de nivel inicial (A1 y A2)[1] cuya L1 es el inglés. La muestra se extrajo de un corpus de acceso público y los resultados indicaron que los estudiantes etiquetados dentro del nivel A2 cometieron el doble de errores en comparación con sus homólogos de A1. Esto nos lleva a reflexionar sobre la necesidad de abordar el fenómeno de la interferencia lingüística en la planificación didáctica para evitar futuras fosilizaciones. Según esta investigación, los tipos de errores que deberían priorizarse son los morfológicos y léxico-semánticos (criterio gramatical) y los de selección incorrecta y de orden inverso (criterio lingüístico).
María del Carmen Méndez Santos (2021). Introducción a la lingüística aplicada para la enseñanza del español: 101 preguntas para ser profe de ELE. Madrid: Edinumen. 247 pp.
Authors: Hidalgo Gallardo Matías
Published: May 2022

Reseña de la obra de María del Carmen Méndez Santos (2021). Introducción a la lingüística aplicada para la enseñanza del español: 101 preguntas para ser profe de ELE. Madrid: Edinumen. 247 pp.
Amando López Valero, Eduardo Encabo Fernández, Isabel Jerez Martínez, Lourdes Hernández Delgado (2021). Literatura infantil y lectura dialógica. La formación de educadores desde la investigación. Barcelona: Octaedro. 138 pp.
Authors: Regueiro Salgado Begoña
Published: May 2022

Reseña de la obra de Amando López Valero, Eduardo Encabo Fernández, Isabel Jerez Martínez, Lourdes Hernández Delgado (2021). Literatura infantil y lectura dialógica. La formación de educadores desde la investigación. Barcelona: Octaedro. 138 pp.
Jaume Centelles Pastor (2020). El abrazo de la literatura. Itinerarios lectores para infantil y primaria. Barcelona: Graó. 181 pp.
Authors: López Hernández Beatriz
Published: May 2022

Reseña de la obra de Jaume Centelles Pastor (2020). El abrazo de la literatura. Itinerarios lectores para infantil y primaria. Barcelona: Graó. 181 pp.
Para una didáctica integrada de las hablas andaluzas y el español de América
Authors: Ramírez Quesada Estrella
Published: May 2022

Más allá de la polémica, hoy superada, en torno al denominado andalucismo del español de América, en este artículo se presenta una propuesta didáctica para la enseñanza media con el fin de trabajar estas variedades del español de manera integrada. Ello favorece una visión más cercana a la realidad del funcionamiento de la variación lingüística y permite, a través del conocimiento histórico –perspectiva a menudo eliminada de la enseñanza de la lengua en secundaria–, fomentar un aprecio por la diversidad lingüística basado en el conocimiento y no solo en la valoración externa. Así, tras la introducción y el marco teórico que sustentan la propuesta didáctica, se ofrece una secuenciación de actividades que pueden realizarse en su conjunto o de manera selectiva para trabajar las hablas andaluzas y el español de América, además de una serie de conclusiones entre las que cabe destacar la adaptabilidad de las actividades y los recursos a aulas de diferentes niveles y contextos educativos.
El uso de las interjecciones propias e impropias por estudiantes de ELE: frecuencias de uso y valores reflejados en el corpus CAES
Authors: Sánchez Morillas Carmen María , Valero Fernández Pilar
Published: May 2022

Dentro de la metodología comunicativa de la enseñanza de lenguas extranjeras o segundas lenguas se ha llevado a cabo un especial énfasis en la enseñanza de distintos componentes lingüísticos desde la perspectiva analítica del nivel de lengua del discente. No obstante, dentro del nivel gramatical, no podemos negar que existen partículas, en este caso las interjecciones, que todavía quedan relegadas al olvido en los manuales de español u otros materiales de enseñanza. Por este motivo, en esta investigación nos centramos en ofrecer el uso que los estudiantes de ELE hacen de las mismas en función de su nivel de lengua (desde el nivel A1 hasta el nivel C1, según el MCER), así como mostrar el inventario de interjecciones propias e impropias que conocen y emplean en sus textos escritos, la frecuencia de uso que hacen de estas, la función con la que son empleadas y, por último, las particularidades que presentan. Para la ejecución de dicho análisis de investigación, tanto de carácter cuantitativo como cualitativo, se partirá de la última versión (1.3., de abril 2020) de los datos extraídos del Corpus de aprendices de español como lengua extranjera (CAES), elaborado por la Universidad de Santiago de Compostela a partir de las producciones escritas de estudiantes extranjeros de los diferentes niveles lingüísticos y de seis lenguas maternas diferentes: árabe, chino mandarín, francés, inglés, portugués y ruso.
Bibliotecas, editoriales y LIJ en la red: análisis bajo el prisma del fomento lector
Authors: Vila Carneiro Zaida , Martín-Macho Harrison Ana
Published: May 2022

En este trabajo se compara, de forma cuantitativo-cualitativa, la interacción de las bibliotecas y las editoriales de literatura infantil y juvenil con el público infantojuvenil a través de las redes sociales. Se ofrece un análisis cuantitativo de su presencia en redes sociales, acompañado de una descripción cualitativa de las tendencias predominantes en el uso que estas instituciones, mediadoras de lectura, hacen de las redes sociales. En concreto, se ha analizado la presencia en redes de las 15 editoriales que aparecen en el directorio de editoriales juveniles de la Biblioteca Nacional de España, así como de 19 bibliotecas públicas españolas, una por cada comunidad y ciudad autónoma, con una activa presencia en redes sociales y en cuyos perfiles destacan actividades e información destinadas a un público infantojuvenil. Se señalan ejemplos de buenas prácticas y de otras mejorables.
Immediate enforcement of judgments in the Republic of Moldova
Authors:   University of European Studies of Moldova, Prisac Alexandru
Published: May 2022

In this article, we have analyzed the grounds for the immediate execution of court decisions and their assurance. We have highlighted the most essential aspects that can appear in the judicial practice of the immediate execution of court decisions. Given the fact that the purpose of the immediate execution of the judgment is to avoid the risk of patrimonial vulnerability of the creditor, we also analyzed certain aspects related to ensuring the execution of the judgment.
A Validated Stability Indicating RP-HPLC Method for Simultaneous Determination of Lopinavir and Ritonavir in Bulk and Tablet Dosage Form
Authors: Prasanthi Prasanthi , Gowri Sankar Dannana
Published: May 2022

A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Lopinavir and Ritonavir in its pure form as well as in tablet dosage form. Chromatography was carried out on a Kromasil C18 (4.6 x 250mm, 5µm) column using a mixture of TEA buffer (pH 4.0), Methanol in proportion 65:35 v/v as the mobile phase at a flow rate of 1.0ml/min, the detection was carried out at 227nm. The retention time of the Lopinavir and Ritonavir were found to be 2.079, 4.045 min respectively. The method produce linear responses in the concentration range of 5-35µg/ml for both Lopinavir and Ritonavir. The method precision for the determination of assay was below 2.0% RSD. The method is useful in the quality control of bulk and pharmaceutical formulations. The optimized method was validated and proved to be suitable for the quality control of the mentioned drugs in their different pharmaceutical dosage forms, according to ICH guidelines. The developed method was found to be fairly precise, rapid and economical for simultaneous estimation of Lopinavir and Ritonavir when compared with the reported method.
Applications of Fourier Transform Infrared and UV-Visible Spectroscopy for the demonstrating sameness of Ganirelix peptide in Liquid Injection Formulation
Authors: Ummiti Kumarswamy , Kumar J.V. Shanmukha
Published: May 2022

Ganirelix (or Ganirelixum) is a synthetic peptide molecule made up of covalently bonded 10 amino acids. The structural order of peptides determines their biological properties. The minor change in the structure of therapeutic peptides can have a significant impact on their biological behaviors. In this regard, the ganirelix drug product was sterilized at 121°C for 15 mins and further exposed to thermal and humidity at 25°C/60%RH and 40°C/75% RH for 6 months. The ganirelix was isolated using flash chromatography and freeze- dried. We applied Fourier transform infrared (FTIR) and Ultraviolet -Visible (UV-Vis) spectroscopic techniques to investigate temperature and humidity effects on the chemical structure of Ganirelix. FTIR scans were conducted in the wave number range of 4000 – 400cm-1 and UV scans were conducted in the wavelength range of 190 – 400nm. The attained IR stretching vibrations, maximum UV absorbance results, overlayed IR and UV-Vis spectra of Ganirelix in temperature stressed generic drug product is closely comparable to reference listed drug (RLD). In addition, it showed homology in the finger print region of the FTIR with those of the reference listed drug (RLD).
Transanethole protects against Global Cerebral Ischemia through its Anti-inflammatory and Anti apoptotic activity
Authors: Saila. M Hima , Thakur Santhrani
Published: May 2022

Aim and Objective: In this research study, transanethole at a dose of 250 and 500mg/kg p.o was investigated for its potency against Bilateral Common Carotid Artery occlusion (BCCAO) for 1 hr accompanied by 22 hrs reperfusion. Method: Healthy Albino Wistar rats (200–250gm) were divided randomly into 4 groups (n=9). Group I was considered as sham control, received 2% tween 80p.o, group II was considered as ischemic- reperfusion (disease control) and received 2% tween 80p.o and group III and IV were considered as prophylactic treatment groups and received transanethole at doses of 250mg/kg, p.o and 500mg/kg, p.o. respectively. After pretreatment with transanethole for14 days, rats were subjected to bilateral common carotid artery occlusion (BCCAO) for 1 hour accompanied by 22 hr reperfusion (I/R). After 22 hrs of reperfusion, motor coordination, behavioral assessment, infarct area, brain water content, excitatory mediators, inflammatory and apoptotic markers were determined. Results: Transanethole improved the motor coordination, lowered the brain water content, infarction volume and attenuated the levels of excitatory mediators. Western blotting analysis was performed to identify the proinflammatory mediators (TNF α, p38 MAPK), anti-inflammatory cytokine IL 10 and apoptotic marker proteins (Caspase 3, Bcl-2 and Bax) in brain tissue. Prophylactic treatment with trans anethole significantly down regulated the expressions of TNF-α, caspase 3, Bax, dephosphorylated p38 MAPK and upregulated the expressions of Bcl-2, IL 10 in a dose dependent manner in comparison with disease control group. Conclusion: An anti-inflammatory and anti- apoptotic activity of transanethole protected from cerebral ischemia reperfusion injury.
Preliminary Phytochemical Screening and Infra-Radiation Test of Crude the Leaves of Nothophanax scutellarium Merr., Moringa oleifera and Piper betle L.
Authors: Sriyanti Cut , Nizwan Siregar Tongku , Mudatsir Mudatsir , Gani Azhari
Published: May 2022

Biodiversity in Indonesia is home to medicinal plants in the world, including Nothopanax scutellarium Merr., Moringa oliefera Lam., Piper betle L. Several researchers have examined the active compounds contained in these plants. This study focused on preliminary phytochemistry and FTIR analysis of leaf extracts of Nothopanax scutellarium Merr., Moringa oliefera Lam., Piper betle L. Phytochemicals were extracted with ethanol 70% by maceration. The results showed that the active compounds of flavonoids, steroids, tannins, phenols, saponins, and alkaloids were present in the three leaves. FTIR analysis observed the main peak at wavenumber 3623.44 cm-1 in the mangkokan leaf extract, wavenumber 3690.64 cm-1 in the moringa leaf extract, and wavenumber 3683.89 cm-1 in the piper betle leaf extract. All of which showed the O-H phenol functional group.
Storytelling corporativo: una revisión crítica de los enfoques de investigación y la metodología en la literatura académica del 2011 al 2020
Authors: Atarama-Rojas Tomás , Robledo-Dioses Kelly , López-Hermida Russo Alberto
Published: May 2022

Los académicos de diferentes campos del conocimiento están de acuerdo en que el storytelling ha ganado especial relevancia en el contexto actual. Esto resulta evidente en la comunicación corporativa, donde se ha instaurado ya el término de storytelling corporativo, para hacer referencia a las historias que las empresas cuentan a sus diferentes grupos de interés (stakeholders). En este campo, se han encontrado diversas investigaciones académicas que desde diferentes enfoques y con distintas metodologías tratan de dar luces sobre la naturaleza, los alcances y las limitaciones del storytelling en el mundo de la empresa. Esta investigación presenta una revisión crítica de esta literatura académica y destaca que la ausencia de unidad conceptual y de aproximaciones metodológicas validadas por la comunidad científica han hecho del storytelling un tópico del que se escribe mucho, aunque sin ofrecer un conocimiento articulado o soluciones prácticas para su aplicación en el desarrollo de la estrategia de comunicación de la empresa.
通識英文兼任教師之微觀政治策略與利益
Authors: 林孟煒 林孟煒 , Meng-Wei Mavise Lin 洪志成
Published: May 2022

台灣一般大學及技職校院通識英文課程多仰賴兼任教師授課，而教師回應課程管理制度要求呈現質量化教學成果，所採取之教學因應策略是否能維持專業取向仍少有論述。研究用建制俗民誌設計大綱，訪談六位在十三所大學語言中心任教通識英文兼任教師，藉微觀政治視角分析其回應管理之策略。發現：(1)面對各校差異要求，兼任教師採取「配合」或「力求表現」策略，力求表現指教師利用話術或利益交換，說服學生呈現更多成果。(2)相對專任，兼任教師多保持沉默，不讓管理單位感到困擾。(3)採取力求表現策略之動機，來自文化認同利益與自我專業認同利益：文化認同利益改變師生溝通、班級經營及輔導方式，而自我專業認同利益讓其在多變教學環境中自我強化。

 

Teaching of General English courses at universities and at universities of science and technology in Taiwan relies heavily on part-time instructors. The strategies undertaken by part-time instructors of General English in response to course management regulations affect their teaching practice. The study participants were six part-time General English instructors teaching at 13 university language centers. This study applied the institutional ethnography approach to designing interview guidelines and analyzed the interaction strategies applied by the instructors in response to the language centers’ requirements from the micropolitics perspective. The following was discovered: 1) Most of the educators “went along” with distinct requirements, whereas some chose to “be noticed” and used strategies, such as sales talk or quid pro quo negotiation, to improve student outcomes. (2) The part-time instructors tended to “keep silent” and were careful to “not cause any trouble” even when they found the requirements to be unrealistic. 3) The “being noticed” strategy was associated with cultural-ideological and professional identity interests. Cultural-ideological interests influence the instructor–student interactions, class management, and tutoring strategies. Professional identity interests enable them to think positively and help students in alternative ways when they encounter a frequent change in the teaching context.

 
Uno sguardo al neurosviluppo raggiunto ai 2 anni di età
Authors: Segre Giulia , Costantino Ilaria , Scarpellini Francesca , Tessarollo valeria , Clavenna Antonio , Bonati maurizio
Published: May 2022

When a child develops a psychological disorder, even a mild one, early diagnosis is essential to provide a timely and appropriate intervention that can improve the child’s symptoms and development. Early identification can prevent consequences of differing levels, in the short and long term, in the individual, in their family and in society as a whole. Hence the importance of the paediatrician’s point of view and clinical knowhow in identifying potential disorders early, but also of the parents’ views. It is therefore important to actively involve parents in initial diagnosis. In this regard, within the NASCITA Project, a study branch aimed to build a shared, active approach between parents, paediatricians and neuropsychiatrists/psychologists was activated for the 2-year health assessments (well-child visits) phase. Three tests were used: the M-CHAT-R (Modified Checklist for Autism in Toddlers, Revised) to evaluate language, social skills, behaviour, sensory areas; the PSI-SF (Parenting Stress Index - Short Form) to verify the degree of discrepancy perceived by the parent between the child’s requests and their ability to deal with them properly; the DERS (Difficulties in Emotion Regulation Scale) to highlight the difficulties of each parent in recognising, interpreting, and managing their emotions. The tests were given to 380 parents (142 couples, 215 mothers and 23 fathers) by 45 family paediatricians during the well-child visit held at two years of age. In all, 33 children (9%) resulted at risk, with a score of ≥ 3, 1 of whom was found to be at high risk. For 64 children (16.8%) at least one of the parents tested positive for PSI-SF and for 19 (5%) children at least one parent tested positive with the DERS. After combining the results obtained from the three tests and the clinical evaluation and by assessing the child’s condition with respect to those results, the paediatrician can provide the parents with a concise description of what emerged and the specialist with a summarised report. Such an effort leads to timely, shared communication within the parent-paediatrician-neuropsychiatrist triad that includes specificity of intervention and that can contribute to the effectiveness of the response.
Sindrome dello spettro autistico e macrocefalia: la sindrome di Cowden
Authors: Iacono Alessandra , Parmeggiani Giulia , Mellino Chiara , Moschettini Valerio , Marchetti Federico
Published: May 2022

The paper reports the story of a 4-year-old boy presenting with macrocephaly and autism spectrum disorder. Genetic testing for an overgrowth syndrome revealed the presence of a heterozygous mutation in the PTEN gene, responsible for Cowden syndrome. The clinical case is an example of the need to investigate all cases of autism spectrum syndrome that may present an underlying genetic mutation, with important care implications that may derive from it.
Pianificazione condivisa di cure: quando il meglio riesce a essere amico del bene
Authors: Fachin Alice , De Zen Lucia
Published: May 2022

The authors describe a favourable experience of home management by parents of a syndromic child with highly recurrent, difficult to treat seizures.
Una tosse… a clacson
Authors: Colussi Lara
Published: May 2022

The case of a ten-year-old boy with persistent cough is presented. The diagnosis of bizarre disruptive honking cough was eventually made. The possible clinical features of the somatic cough are discussed.
O RECEPTOR B2 DE CININA NÃO EXERCE EFEITOS RENOPROTETORES EM MODELO DE RABDOMIÓLISE INDUZIDA POR GLICEROL EM CAMUNDONGOS
Authors: Macedo Michel Monteiro , França Erivelton Fernandes , Mafra Fernando Francisco Pazello , da Silva Romildo Torres , Gomes Pedro Paulo Gattai
Published: May 2022

Investigamos o papel protetor do receptor B2 de cininas em modelo animal com rabdomiólise induzida por glicerol. Camundongos machos C57Bl/6 (n=28) foram separados em 4 grupos: selvagens não tratados, knockout B2 não tratados, selvagens tratados e knockout B2 tratados. Aqueles tratados com glicerol receberam uma injeção de glicerol (50% v/v, 7 mL/ kg, i.m.). Após 48 h, urina e sangue foram coletadas para dosagem de creatinina e ureia. Rins foram extraídos para avaliação histológica, e níveis de expressão de mRNA de receptores B1 e B2 de cininas e mediadores inflamatórios foram medidos por qPCR. A creatinina e ureia séricas mostraram diferenças entre camundongos selvagens não tratados e tratados (0,66 ± 0,04 vs 2,61 ± 0,53 mg/dL, P < 0,01; 33,51 ± 2,08 vs 330,2 ± 77,7 mg/dL, P 30 vezes, 31,34 ± 8,9) nos rins. Animais injetados com glicerol apresentaram maior grau de lesão que os animais não tratados. Camundongos selvagens e knockout tratados apresentaram lesão renal, com comprometimento da função renal. Camundongos knockout B2 tratados não apresentaram um fenótipo diferente nos marcadores de lesão renal, quando comparados ao grupo tratado selvagem. Concluímos que o receptor B2 de cininas não tem papel protetor na lesão renal.
Analysis and evaluation of cardiovascular and gastrointestinal risk of nonsteroidal anti-inflammatory drugs selective and non-selective cyclooxygenase inhibitors
Authors: Martín González Antonio , Martín Arias Luis Hermenegildo , Sanz Fadrique Rosario , Salgueiro Vázquez Esther
Published: May 2022

Introduction: the aim of this study is to review the current evidence on the clinical use of NSAIDs, coxibs and nonselective, and to evaluate its cardiovascular (CVR) and gastrointestinal risk (GIR) by means of a meta-analytic procedure.

Materials and methods: cohort and case-control studies showing CVR and GIR associated with NSAIDs versus no treatment were selected. We estimated the pooled RR and the 95% confidence interval (CI) for all NSAIDs as a whole and individually.

Results: both coxibs (RR, 1.22 [95%CI, 1.17-1.28]) and nonselective NSAIDs (RR 1.18 [95%CI, 1.12-1.24]) were associated with an increased CVR. The coxibs CVR remained even for low-dose and low-baseline CVR subgroups. Analysis by drug disclosed that rofecoxib (RR 1.39 [95%CI, 1.31- 1.47]), along with diclofenac (RR, 1.34 [95%CI, 1.26-1.42]) and etoricoxib (RR 1.27 [95%CI, 1.12-1.43]) were the NSAIDs associated with the highest CVR.

Gastrointestinal risk meta-analysis showed that coxibs were associated with a GIR increment [RR1.64 (95% CI 1.44-1.86)]. Analysis by drug disclosed that etoricoxib [RR 4.48 (95% CI 2.98-6.75)]presented the highest GIR followed by rofecoxib [RR 2.02 (95% CI 1.56-2.61)] and celecoxib [RR1.62 (95% CI 1.46-1.78)]. GIR was also high for <65 year-old and low-dose coxibs subgroups.

Conclusion: according to our study the use of NSAIDs (coxibs and nonselective) are associated with a similar CVR increment, even for low-dose and low-baseline CVR subgroups. On the other hand, the use of coxibs is associated with a GIR increased, which would be high even for low-dose coxibs and <65-year-old subgroups. The risk would be higher for etoricoxib than for celecoxib and rofecoxib.

Keywords: adverse drug reactions; nonsteroidal anti-inflammatory drugs; cardiovascular risk; meta-analysis; observational studies; cyclo-oxygenase 2 inhibitor; gastrointestinal events
Central and South Asian Energy Projects: Prospects and Challenges for Pakistan
Authors: Ali Haider Saleem
Published: May 2022

After the 2013 elections, the Government of Pakistan (GoP) stepped up its efforts to combat the energy crisis, persisting in the country. Due to limited energy resources and poor infrastructure, Pakistan looked towards resource-rich countries to secure energy supplies. On the other hand, the Central Asian Republics (CARs) have an abundance of energy resources and are looking for the markets to export their surplus energy resources. The Central Asia South Asia-1000 (CASA-1000), Turkmenistan-Afghanistan-Pakistan-India pipeline (TAPI) and Turkmenistan-Uzbekistan-Tajikistan-Afghanistan-Pakistan (TUTAP) electricity project have been launched. The development work on these projects is already underway. These projects are an attempt to promote development. through cooperation. However, there are many obstacles that could impede energy transfer to Pakistan. This paper attempts to examine the impact of these projects on Pakistan’s economic development. It also analyses the measures that have been taken to address the challenges and present some recommendations for ensuring efficient delivery of these projects.
Degrees of Psychological Well-Being among Students of Palestinian Universities in Hebron Governorate
Authors: Al Jundy Nabeel I. , Talahmeh Jbarah A.
Published: May 2022

This study aims at investigating the levels of psychological well-being among Palestinian university students in Hebron District, and adapting Ryff's Psychological Well-being Scales to the Palestinian environment, The researchers applied the Ryff’s Psychlogical Well-being Scales on a simple random sample of (200) students located at three Palestinian universities (Hebron University, Al-Quds open University, & Polytechnic University). Validity was confirmed. Moreover, the reliability of the scale was confirmed by using Cronbach a coefficient. The study concluded that the degrees of Palestinian students' psychological wellbeing were moderate. In addition to that, the study found that there were differences in the degree of psychological well-being according to gender in favor of females, differences according to the type of specialization in favor of students in the human colleges, differences due to the economic level in favor of students with higher incomes, and differences due to the place of residence in favor of villagers students. Furthermore, the study found there were no differences in the average psychological well-being due to the sitting university. Finally, the study has come out a set of recommendations stemming from its results, such as the need to address welfare for Palestinians, especially in crowded cities, as well as the need to motivate university students in science faculties, and to reduce the degrees of tension induced by the difficult context in which Palestinians live.
The Impact of Small Group Instruction on Preschool Literacy Skills
Authors: Abu Al Rub Majedah
Published: May 2022

This study focused on 17 preschool students in a northern Jordan city. Preschoolerswere taught specific literacy skills in a small group instructional setting. The students’ skill level was assessed at the beginning and middle of the school year. The researcher’s goal was to determine if teaching literacy skills in a small group setting would improve the skill level of the preschool students. Results showed that using small groups was an effective way to increase preschool students’ literacy skill levels.
Effectiveness of Computerized Training Program to Develop Skills of Phonology Awareness to Activate Reading and Writing Abilities of a Sample of Talented Students with Learning Disabilities
Authors: Oleimt Enas M.
Published: May 2022

This study aimed to explore the effectiveness of a computerized training program to develop the skills of phonology awareness to activate the reading and writing abilities of a sample of talented students with learning disabilities. The sample consisted of 60 students in the school year 2015-2016. The researcher employed the Phonological and Articulation Disorders Scale (Oliemat and Al-Rosan, 2016) and the computerized training program of phonology awareness (Oliemat and Al-Fayez, 2012). Results revealed statisticaly significant differences in favor of the experimental group. Results also showed statisticaly significant differences in the posttest attributed to age in the phonology awareness level in favor of age category (8-9 years). The study recommended benefiting from these results when preparing remedial, educational, and training programs for students with various disabilities; conducting training programs on computerized software of phonology awareness; designing other computerized software for all types of phonological disorders and other ages of talented students with learning disabilities.
University Service Quality in the Community Service and Continuing Education Center at Sultan Qaboos University: An Empirical Study Using SERVQUAL Scale
Authors: Salah Eldean Nisreen S. , Bartamani Mariyam S.
Published: May 2022

The study aimed to define strategies to achieve university service quality in the Community Service and Continuing Education Center (CSCEC) at Sultan Qaboos University (SQU) using the SERVQUAL scale. The scale examines the gap between expectations and perceptions. The researchers translated the scale and rephrased some of its items in a way that was suitable the study population. The instrument was administered to a random sample of SQU academics, and the CSCEC employers and trainees. Descriptive analysis methods were used in the study in addition to a group of appropriate statistical procedures. The results revealed a high level of quality services that the center provides or plans to povide. The results also indicated that there were no significant differences regarding the demographical variables of type, job and age in all of the service quality dimensions. In addition, the study suggests some strategies to achieve university service quality in the community service and continuing education center at Sultan Qaboos University.
THE QUALITY OF INFORMATION AS THE BASIS OF THE SOCIAL ORDER OF THE POST-INDUSTRIAL SOCIETY IN THE 21ST CENTURY
Authors: Жуйков Андрей Алексеевич , Михайлов Андрей Павлович
Published: May 2022

В статье отмечается, что постиндустриальное общество XXI в. находится в серьезной зависимости от качества информации, так как именно она выступает основой многих современных явлений, процессов, а следовательно - предопределяет функционирование социальных институтов и подсистем. В этой связи существенной проблемой является то, что социальная система не обладает эффективными механизмами противодействия вредной информации, в ней актуализированы многочисленные лакуны, потенциально или реально дисфункциональные по информационному критерию. Это в свою очередь создает информационные риски социальному порядку, стабильности социума. В статье анализируются факторы, оказывающие влияние на снижение качества информации, к числу которых относятся: информационная перегрузка, деятельность агрессивных коммуникаторов, распространение самотранслирующейся информации в виртуальном пространстве, дисфункциональность социальных институтов и социальных подсистем в условиях инновационного развития. Утверждается, что качество информации способно оказывать воздействие на выстраивание параметрики социального порядка. Делается вывод о том, что информационные ресурсы традиционного и инновационного плана требуют концептуального осмысления посредством проведения эмпирических социологических исследований, на основе которых представляется возможным сформировать эффективную систему профилактики и противодействия вредной информации.

The post-industrial society of the 21 century is seriously dependent on the quality of information, since it is information that forms the basis of many modern phenomena and processes, and therefore predetermines the functioning of social institutions and subsystems. In this regard, a significant problem is that the social system does not have effective mechanisms for countering harmful information. Numerous gaps are actualized in it, potentially or really dysfunctional according to the information criterion. This, in turn, creates informational risks to the social order and stability of society. The publication analyzes factors influencing the decrease in the quality of information. Those are information overload, the activities of aggressive communicators, the spread of self-relayed information in the virtual space, and the dysfunctionality of social institutions and social subsystems in conditions of innovative development. The research shows that the quality of information can influence the construction of social order parameters. It is concluded that the information resources of the traditional and innovative plan require conceptual understanding through empirical sociological research, based on which it is possible to form an effective system for preventing and combating harmful information.
The effect of smart phone use on student health status
Authors: Suman Miss , Devasirvadam S. Victor
Published: May 2022

The aim of the study is to assess the impact of smart phones use on health status among students. Material and methods: Quantitative research approach was adopted to assess the impact of Smart Phone on Health Status among student: A study of self- financing colleges of J&K. The present study was conducted at selected nursing college in J&K. Purposive sampling technique was used to select the students who were selected from nursing colleges. The tool was developed by keeping in mind the objectives of the study and prepared after extensive review of literature, internet sources and through discussion with guide, co-guide and opinions of various experts in the field of Medical health nursing, Psychology, psychiatric, social and preventive medicine. The reliability of the tool was assessed by Cronbach’s alpha method, which was Likert’s scale impact of smart phone on Physical Health Status (r=.845), Likert’s scale impact of smart phone on Psychological Health Status (r=.764). The tool was found to be reliable. The pilot study was carried out on 30 samples to assess the feasibility for conducting main research study and to assess the relevancy of the tool. The pilot study was conducted at BEE ENN nursing college, Jammu.
Sociological theories of juvenile delinquency
Authors: Raturi Smriti , Rastogi Sachin
Published: May 2022

The present paper studies Juvenile Delinquency from the perspective of the sociological theories of criminology. Since, Juvenile Delinquency as a concept originates from the societal parameters, and flourishes within the society; it correlates with the societal framework; it's imperative to understand how Delinquency has taken its present shape. Therefore, the paper discusses the sociological theories to understand the relationship between crime to Delinquency. The present paper also tries to research whether one or two theories can suffice the need to understand Juvenile Delinquency or whether all the theories should be studied in correlation with each other in different societal frameworks.
Analysis of the world scientific production on educational psychology (2000-2022)
Authors: Arias-Chavez Dennis , Ramos-Quispe Teresa , Castillo Nilo Albert Velásquez
Published: May 2022

The aim of the study was to characterize the world scientific production on Educational Psychology in the Scopus and Web of Science databases, between January 2000 and January 2022. We worked with a universe of 526 documents from the WoS database and 829 from Scopus, extracted from 167 and 316 sources respectively. Regarding the number of authors, Scopus presents 1336 and WoS, 925. Single-authored documents total 294 in Scopus and 229 in WoS. The collaboration index between authors is slightly higher in WoS (2.64) compared to 2.39 in Scopus. The authors Mok, M. and Mackay T., and the journals Educational and child psychology and Psychiatria Danubina stand out. The United States is the most productive country in terms of scientific evidence. The type of scientific production that stands out the most is original articles. The growth of scientific production is corroborated by the emergence of the pandemic and its impact on education, requiring the support of psychology.
Hubungan Pengetahuan Remaja Putri Terhadap Bahaya Kehamilan Pada Usia Remaja
Authors: Indah Indah Dwi Ayuni , Islami Dian , Jannah Miftakhul , Putri Adilla , Nurhasanah
Published: May 2022

Latar belakang: Masa remaja merupakan masa transisi dari masa kekanak-kanakan ke masa dewasa yang diawali dengan pubertas. Pada masa ini terjadi berbagai perubahan, baik dari segi fisik, social, maupun emosional. Salah satu faktor yang mempengaruhi masalah kehamilan remaja yaitu tingkat pengetahuan remaja. Kurangnya pengetahuan mengenai seks dan kesehatan reproduksi mendorong remaja yang memiliki pengetahuan kurang untuk melakukan perilaku negative seperti seksual pranikah yang akan menyebabkan kehamilan pada usia remaja.
Tujuan: Untuk menganalisa hasil sebuah penelitian yang berfokus pada pengetahuan remaja putri terhadap bahaya kehamilan pada usia remaja.
Metode: Penulisan literature review ini dengan pencarian artikel nasional, melalui penelusuran internet melalui google cendikia,ensiklopedia menggunakan kata kunci yang digunakan dengan pencarian artikel yaitu pengetahuan, dan kehamilan remaja.
Hasil: berdasarkan literature review menunjukkan rendahnya tingkat pengetahuan remaja terhadap faktor penyebab kehamilan pada masa remaja, terdapat peningkatan pengetahuan setelah diberikan informasi berkaitan dengan risiko kehamilan pada usia muda.
Kesimpulan: Dari hasil literature review ini disimpulkan dengan adanya pengetahuan remaja yang masih minim, diharapkan kepada seluruh remaja agar lebih aktif dalam mencari informasi-informasi yang terkait tentang bahaya kehamilan dimasa usia muda, sehingga pada remaja itu sendiri dapat mengetahui dan menghindari bahaya yang akan terjadi dan  kemungkinan disebabkan karena kehamilan di usia muda.
Analisis Faktor-Faktor Yang Berpengaruh Terhadap Stres Kerja Perawat Pada Masa Pandemik Covid-19
Authors: Trisnawati Elis , Rindu  , Solehudin
Published: May 2022

Latar Belakang: Pandemi dapat memiliki dampak psikologis yang signifikan pada perawat, mereka sangat penting dalam melaksanakan perawatan kesehatan. Penelitian sebelumnya telah menunjukkan bahwa pandemi memperburuk stres yang dirasakan oleh perawat, karena mereka mengatasi tuntutan emosional, fisik, dan kognitif yang intens. Stres merupakan respon psikologis dan fisiologis terhadap suatu stressor yang bersipat negatif, tekanan emosional, mental maupun trauma.
Tujuan: Penelitian ini bertujuan mengetahui faktor-faktor yang berhubungan dengan stres kerja perawat pada masa pandemik Covid-19 di Rumah Sakit X Bogor tahun 2021.
Metode: Jenis penelitian ini bersifat analitik korelasi dengan pendekatan cross-sectional dengan jumlah responden 131. Uji statistik dilakukan uji regresi logistik.
Hasil: penelitian menunjukan bahwa didapatkan perawat yang mengalami stres kerja ringan dan sedang sebanyak 129 responden (85%) dan mengalami kecemasan berat sebanyak 2 responden (1,5%). Faktor-faktor stres yang berpengaruh terhadap stres kerja perawat diantaranya usia (p-value = 0,000) dan pendidikan (p-value = 0,011). Faktor- faktor stres yang terdiri dari umur, pendidikan, secara bersamaan mempengaruhi stres kerja perawat.
Kesimpulan: faktor yang mempengaruhi stres kerja di masa pandemic yaitu umur dan dan pendidikan pada perawat di Rumah Sakit X Bogor.
Analisis Faktor Risiko Kejadian Hipertensi di Wilayah Kota Depok
Authors: Asri Intan Puspita , Pitriani Salamah Nurul , Maryanah Putri Anna , Putri Nabila E Shofia , Khairunnisa Aisyah , Afifah Faidah , Kusumastuti Istiana
Published: May 2022

Latar Belakang: Hipertensi adalah salah satu penyakit tidak menular yang sering disebut “the silent killer” karena sering terjadi tanpa keluhan sehingga tidak disadari oleh penderita, kemudian mendapatkan dirinya memiliki penyakit penyulit atau komplikasi dari hipertensi. Kasus hipertensi menurut Data WHO 2015 menunjukkan sekitar 1,13 miliar orang didunia dan diperkirakan pada 2025 ada 1,5 miliar orang yang terkena hipertensi serta setiap tahun ada 9,4 juta orang meninggal akibat hipertensi.
Tujuan: Penelitian ini dilakukan bertujuan untuk menganalisis faktor risiko kejadian hipertensi di wilayah Kota Depok.
Metode: Penelitian ini menggunakan metode kualitatif yang dilaksanakan secara online melalui observasi google formulir (kuesioner). Pengolahan data yang dilakukan dari data sekunder (profil kesehatan kota depok 2019 dan jurnal pendukung lain) dan data primer (kuesioner – google formulir) menggunakan microsoft excel
Hasil: Hasil dari penelitian ini menunjukkan bahwa faktor genetic, faktor perilaku, faktor pelayanan kesehatan menjadi faktor resiko dalam kejadian hipertensi di wilayah kota Depok. Cakupan informan yang mengalami kejadian penyakit hipertensi adalah 98 (9,6%) dari 207 (21%) yang memiliki resiko penyakit genetik.
Kesimpulan: faktor terbesar yang berhubungan dengan kejadian hipertensi di Kota Depok yaitu kurangnya aktivitas fisik sebanyak 54 orang dari 98 kejadian hipertensi dan tidak rutin cek kesehatan sebanyak 59 orang dari 98 kejadian hipertensi. Untuk meningkatkan aktivitas fisik dan cek kesehatan secara rutin adalah dengan melakukan penyuluhan mengenai pola hidup sehat yang baik agar masyarakat mau memperbaiki pola hidupnya dan terhindar dari resiko penyakit hipertensi.
Hubungan Sumber Informasi, Dukungan Teman Sebaya dan Sikap Remaja Putri Terhadap Perilaku SADARI
Authors: Hidayani  , Jannah Miftakhul , Patras Kuswati
Published: May 2022

Pendahuluan : Perilaku SADARI merupakan  upaya yang dilakukan untuk deteksi dini kanker payudara dengan melakukan pemeriksaan pada payudara sendiri dengan cara meraba dan melihat apakah terdapat benjolan atau massa pada payudaranya.
Tujuan : Untuk mengetahui hubungan antara sumber informasi, dukungan teman sebaya dan sikap remaja putri terhadap perilaku pemeriksaan payudara sendiri (SADARI), pada santri putri di Ponpes X Kab. Pringsewu, Prov. Lampung tahun 2021.
Metode : Jenis penelitian ini menggunakan kuantitatif dengan desain penelitian deskriptif analitik melalui pendekatan Cross-Sectional. Dan analisis pengolahan data menggunakan uji Chi-Square. Serta sampel dalam penelitian ini menggunakan Total Sampling karena jumlah populasi yang kurang dari 100 sehingga populasi dijadikan sampel seluruhnya yaitu santri putri kelas 1 dan 2 Tsanawiyah yang berjumlah 72 orang.
Hasil : Hasil penelitian menunjukkan bahwa 37 responden (52,4%) remaja putri dengan perilaku SADARI kurang, 38 responden ( 52,8%) mendapat sumber informasi, 40 responden (55,6%)  tidak mendapat dukungan teman sebaya, dan 38 responden ( 52,8%) memiliki sikap positif.
Kesimpulan : Hasil penelitian menunjukkan terdapat hubungan signifikan  antara variabel sumber informasi dengan nilai (p-value 0,001) dan (OR 6,019), Dukungan teman sebaya dengan nilai (p-value 0,005) dan (OR 4,569), Sikap dengan nilai (p-value 0,004) dan (OR 4,615) terhadap Perilaku SADARI pada Santri Putri di Ponpes X Kab. Pringsewu, Prov. Lampung tahun 2021.