bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluasi Kebijakan Bukan Penerima Upah dalam Program Jaminan Hari Tua Di BPJS Ketenagakerjaan Palembang
Authors: Elvira Gustia Putri  , Doris Febriyanti  , Sanny Nofrima
Published: December 2024

Penelitian ini bertujuan untuk mengevaluasi kebijakan yang diterapkan terhadap pekerja bukan penerima program Jaminan Hari Tua (JHT) oleh BPJS Ketenagakerjaan di kota Palembang. Kebijakan ini penting untuk ditinjau mengingat adanya perbedaan perlindungan sosial bagi pekerja yang tidak terdaftar dalam program JHT. Metode penelitian yang digunakan adalah metode deskriptif kualitatif dengan pendekatan studi kasus. Data diperoleh melalui wawancara mendalam dengan sejumlah pekerja dan perwakilan dari BPJS Ketenagakerjaan, serta analisis dokumen terkait. Hasil penelitian menunjukkan bahwa terdapat beberapa kendala dalam implementasi kebijakan, termasuk kurangnya sosialisasi program, rendahnya kesadaran pekerja akan pentingnya JHT, serta adanya ketidaksesuaian antara kebijakan dengan kondisi riil di lapangan. Penelitian ini menyarankan adanya peningkatan dalam sosialisasi dan edukasi mengenai pentingnya JHT, serta perbaikan mekanisme pendaftaran dan pengawasan untuk meningkatkan cakupan program di kalangan pekerja. Dengan adanya evaluasi ini, diharapkan dapat dihasilkan rekomendasi kebijakan yang lebih efektif dan inklusif bagi perlindungan sosial pekerja di Palembang.
PERAN LAZISMU BANTUL KOTA DALAM MEMBERIKAN PELAYANAN KESEHATAN PADA LANSIA TAHUN 2023
Authors: Apriyani Ella , Mahendra Gerry Katon
Published: December 2024

Lansia ialah individu berusia 60 tahun ke atas. Pemerintah Indonesia berupaya meningkatkan kesejahteraan mereka lewat tetapkan hak atas jaminan sosial melalui Pasal 5 UU No. 13 Tahun 1998. Salah satu hak itu ialah pelayanan kesehatan. studi ini bertujuan mengetahui peran LAZISMU Bantul Kota guna memberi pelayanan Kesehatan pada Lansia dan menganalisis faktor penghambat maupun pendukung LAZISMU dalam pelaksanaan program Kesehatan itu. Metode yang dipakai ialah deskriptif kualitatif penelitian yang menggambarkan suatu hasil dimana penelitian itu berisikan tentang deskripsi, penjelasan, serta validasi terhadap fenomena yang tengah diteliti. dengan teknik penghimpunan data yakni observasi, wawancara,dan dokumentasi. Studi ini memakai teori peran dari Sutarto yang dikutip dalam Rika Elsia Gaurifa (2022) yakni konsepsi peran, harapan peran, pelaksanaan peran, berdasarkan dari hasil studi ini memperlihatkan pelayanan Kesehatan yang diberi LAZISMU Bantul Kota untuk masyarakat umum sudah baik, tetapi tidak untuk pelayanan kesehatan pada lansia karena kurang nya SDM LAZISMU Bantul Kota yang menjadi hambatan untuk berjalan nya program itu Namun program kesehatan itu juga memiliki pendukung yaitu tingkat keberhasilan LAZISMU dapat diukur dari jumlah dana zakat, infaq dan sedekah yang berhasil dikumpulkan dari masyarakat.
Eksplorasi Strategi Branding dalam Meningkatkan Citra Perusahaan di Era Digital
Authors: Umam Assa’ady M Chothibul , Febriana Widia , Wardi Putri Amalia , Talidobel Susilo , Nirwana Baiq Nadia
Published: December 2024

Penelitian ini bertujuan untuk mengeksplorasi strategi branding digital yang diterapkan oleh perusahaan di Indonesia dalam upaya meningkatkan citra merek mereka di era digital. Dalam penelitian ini, pendekatan kualitatif deskriptif digunakan untuk menganalisis data yang diperoleh dari wawancara mendalam, observasi, dan studi dokumentasi pada Perusahaan PT Rinjani Royal Cosmetindo yang aktif dalam penerapan branding digital. Hasil penelitian menunjukkan bahwa penggunaan media sosial, e-WOM (Electronic Word of Mouth), dan personalisasi konten merupakan strategi utama dalam membangun citra merek. Media sosial memberikan platform yang efektif untuk berinteraksi dengan konsumen, sementara e-WOM membantu memperkuat citra positif merek melalui ulasan dan rekomendasi pelanggan. Selain itu, personalisasi konten memungkinkan perusahaan untuk menciptakan pengalaman yang relevan bagi setiap konsumen, yang dapat meningkatkan loyalitas dan kepuasan pelanggan. Meskipun demikian, tantangan utama yang dihadapi oleh perusahaan dalam penerapan branding digital adalah kesulitan mengukur dampak langsung terhadap penjualan serta ketidak konsistenan antara branding digital dan tradisional. Untuk mengatasi tantangan dalam penerapan branding digital oleh PT Rinjani Royal Cosmetindo adalah dengan mengembangkan sistem analitik yang lebih efektif untuk mengukur dampak langsung dari strategi branding digital terhadap penjualan. Hal ini dapat dilakukan melalui penggunaan tools analisis data dan pengukuran ROI (Return on Investment) yang lebih terintegrasi. Selain itu, perusahaan perlu melakukan harmonisasi antara branding digital dan tradisional dengan menyusun pesan yang konsisten di seluruh saluran komunikasi, memastikan identitas merek tetap kuat dan mudah dikenali oleh konsumen. Penelitian ini menyimpulkan bahwa branding digital memiliki peran yang sangat penting dalam meningkatkan citra perusahaan, namun perusahaan perlu terus beradaptasi dengan perkembangan teknologi dan tren digital untuk memaksimalkan potensi dari strategi ini.
TANTANGAN PERTAHANAN NASIONAL MENUJU INDONESIA EMAS 2045
Authors: Ahmad Fanani  , I Wayan Midhio  , Afrizal Hendra
Published: December 2024

Golden Indonesia 2045 is a long-term vision launched to mark 100 years of Indonesian independence. This vision covers various aspects of development, including economic, social and defense. National defense policy is one of the key elements in ensuring the achievement of this vision, considering the importance of national stability and security as the foundation for sustainable development. This research aims to see the challenges in the aspect of national defense towards a golden Indonesia 2045 and the role of national defense in realizing a golden Indonesia 2045. The research method used is a literature study involving analysis of documents, books, journal articles and information from official websites. Indonesian national defense. The findings obtained by researchers in this research are that there are several challenges faced by Indonesian national defense such as Economic and Resource Challenges: Defense Budget Limitations and the Need for Military Modernization, Institutional and Bureaucratic Challenges: The Need for Reform of Defense Institutions and Bureaucracy and Budget Limitations and Priorities National: Balancing Economic Development and Defense Investment. Meanwhile, the role of national defense in realizing a Golden Indonesia 2045 is implementing Defense Diplomacy in the context of international cooperation in maintaining regional security and building national resilience and responding to non-conventional threats. Non-conventional threats such as terrorism, separatism, cyber attacks and climate change.
Analisis Self Confidence pada Pembelajaran Matematika Siswa Madrasah Aliyah
Authors: Ismiasih Novi , Mustika Tito Nur
Published: December 2024

Students are often afraid of failing and making mistakes, this fear triggers students' low self-confidence. Confidence or self confidence is an important aspect of a person's personality. Self confidence is a part that students must have in order to be able to carry out mathematics learning well. Students who have self confidence in studying mathematics will get maximum results, because self confidence plays an important role in student academic achievement. This research uses qualitative with descriptive type. The research subjects were 23 class XII students majoring in languages. The instrument in this research was a non-test instrument, namely a mathematical self confidence questionnaire consisting of 12 statements. The results showed that (1) 79.02% believed in their own abilities, (2) 52.9% acted independently in making decisions (3) 65.8% had a positive self-concept, (4) 82.76% were brave express an opinion. Meanwhile, the average percentage of all indicators is 70.12% who have good self-confidence and 29.88% lack self-confidence in learning mathematics.
Ảnh hưởng của phương pháp bào chế đến tác dụng an thần của Viễn chí trên thực nghiệm
Authors: Thùy Nguyễn Thị Phương , Khải Danh Đức , Giàu Lư Bích Ngọc , Hiệp Vũ Thị
Published: December 2024

Viễn chí có tác dụng an thần ích trí, hóa đàm, chỉ khái, giải độc, nhưng khi dùng sống có thể gây kích ứng dạ dày và tổn thương đường ruột. Để giảm độc tính và tăng hiệu quả điều trị, Viễn chí được bào chế bằng nhiều phương pháp, trong đó Bộ Y tế Việt Nam hướng dẫn hai phương pháp là Viễn chí sao cám và Viễn chí chích Cam thảo. Trong nghiên cứu này, tác dụng an thần được đánh giá bằng mô hình sáng tối và rotarod. Kết quả cho thấy Viễn chí phiến không thể hiện tác dụng an thần ở liều thử nghiệm. Viễn chí sao cám và Viễn chí chích Cam thảo đều thể hiện tác dụng an thần ở liều uống 2,88 g dược liệu/kg. Viễn chí sao cám có tác dụng an thần tương đương với Viễn chí chích Cam thảo trong các mô hình thử nghiệm. Sự gia tăng hiệu quả an thần có thể liên quan đến việc tăng hàm lượng saponin và tenuifolin sau khi chế biến. Như vậy, các phương pháp bào chế có ảnh hưởng đáng kể đến tác dụng an thần của Viễn chí. Những phát hiện này cung cấp bằng chứng để tối ưu hóa việc sử dụng Viễn chí trong lâm sàng.
Xây dựng và thẩm định quy trình định lượng đồng thời indapamid và perindopril tert-butylamin trong viên nén bằng phương pháp sắc ký lỏng hiệu năng cao
Authors: Linh Đinh Thị Lan , Nghĩa Nguyễn Thành
Published: December 2024

Nghiên cứu này được thực hiện nhằm xây dựng và thẩm định quy trình định lượng đồng thời indapamid và perindopril tert-butylamin trong viên nén bằng phương pháp sắc ký lỏng hiệu năng cao (HPLC) phù hợp với điều kiện cơ sở vật chất sẵn có. Một phương pháp đã được xây dựng để định lượng đồng thời indapamid và perindopril tert-butylamin với pha động gồm acetonitril-nước acid percloric 0,01 % (33:67), pha tĩnh là cột HiQ sil C18HS (250 mm × 4,6 mm, 5 µm), nhiệt độ cột 35 ℃, tốc độ dòng 1,2 mL/phút, thể tích tiêm mẫu 10 µL, đầu dò PDA, bước sóng phát hiện 215 nm. Điều kiện xử lý mẫu: chiết bằng ethanol, không siêu âm. Phương pháp đã được thẩm định đạt yêu cầu theo hướng dẫn của ICH gồm tính phù hợp hệ thống; độ đặc hiệu; tính tuyến tính từ (5-35) ppm và (10100) ppm lần lượt cho indapamid và perindopril tert-butylamin với hệ số tương quan R > 0,9999; giới hạn phát hiện và giới hạn định lượng lần lượt là 0,59 ppm và 1,79 ppm với indapamid và 1,47 ppm và 4,45 ppm với perindopril tert-butylamin; độ đúng, tỷ lệ thu hồi (98,0-102,0) %; độ chính xác SD < 2,0 %.
Effects of fish stocking density on water quality and the growth of red tilapia and vegetables in microalgae-aquaponic systems
Authors: Kinh Co Thi , Nho Nguyen Thanh , Hien Vo Thi Dieu , Huy Le Quang , Tung Tra Van , Manh Vu Quang , Hoang Le Thai
Published: December 2024

This study investigates the impact of fish stocking density on water quality, red tilapia (Oreochromis sp.) growth, and mustard green (Brassica integrifolia) growth in microalgae-aquaponics systems. Three densities were tested: D1 (90 fish/m³), D2 (70 fish/m³), and D3 (50 fish/m³). Water quality monitoring showed that TAN, NO₂⁻, and NO₃⁻ levels increased with fish density, while phosphate levels remained relatively stable. D1 had the highest total fish weight gain but a lower weight gain rate (91.9 %) compared to D2 (105.6 %) and D3 (134.1 %). D3 had the highest average weight gain per fish (67.78 g) and the best survival rate (100 %), whereas D1 had the lowest survival rate (94 %). Mustard greens grew best in D1. Microalgae density increased during experimental time, with D3 showing the highest biomass in both the algal and fish tanks. The results suggest that higher fish densities promoted plant growth, while lower densities benefited fish and microalgae, thus offering insights for optimizing recirculating microalgae-aquaponics systems.
Nghiên cứu chế biến rượu chưng cất từ mít Thái thứ phẩm (Artocarpus heterophyllus Lam.)
Authors: Phượng Nguyễn Vân Ngọc , Hùng Nguyễn Tấn
Published: December 2024

Nghiên cứu được thực hiện để khảo sát ảnh hưởng của 3 yếu tố bao gồm tỷ lệ nấm men (0,4 % - 1,2 % (w/v), độ Brix (22-30) và pH (3,6-4,5) đến độ rượu của sản phẩm rượu từ mít Thái. Thử nghiệm được thiết kế theo mô hình Box-Behnken để xác định các điều kiện tối ưu cho quá trình lên men dịch mít. Dịch mít sau lên men được chưng cất để đánh giá một số chỉ tiêu chất lượng của rượu (methanol, aldehyde và cảm quan). Kết quả cho thấy hàm lượng ethanol của dịch mít sau lên men đạt 15,31 % (v/v) khi lên men 9 ngày ở các các điều kiện thích hợp được xác định tỷ lệ men 0,799 %, dịch quả ở 26,71 oBrix và pH 4,06. Chất lượng mít sau chưng cất đạt tiêu chuẩn Việt Nam theo TCVN 7045: 2013 và có chất lượng cảm quan khá. Kết quả nghiên cứu cho thấy, có thể tận dụng nguồn mít Thái thứ phẩm làm nguyên liệu lên men rượu nhằm tạo ra sản phẩm có giá trị gia tăng cũng như góp phần đa dạng hóa sản phẩm và nâng cao giá trị kinh tế cho mít thứ phẩm.
Thử nghiệm lên men nem chua nấm sò vua (Pleurotus eryngii) sử dụng vi khuẩn acid lactic
Authors: Châu Lưu Minh , Tiên Nguyễn Thị Mỹ , Long Bùi Hoàng Đăng , Tiên Đoàn Thị Kiều , Thành Nguyễn Văn , Phong Huỳnh Xuân , Thạnh Nguyễn Ngọc
Published: December 2024

Nấm sò vua (Pleurotus eryngii) là một loại nấm ăn giàu giá trị dinh dưỡng và dược học; quả thể có kích thước lớn, hình dáng đẹp, thịt chắc, dày và hơi giòn. Nghiên cứu này được tiến hành nhằm tuyển chọn chủng vi khuẩn lactic có khả năng lên men và xác định các điều kiện thích hợp để lên men nem chua nấm sò vua. Mười chủng vi khuẩn lactic đã được chọn lọc và các điều kiện lên men thử nghiệm bao gồm nhiệt độ ủ (nhiệt độ phòng, 30 °C, 37 °C), mật độ giống (103, 105, 107 tế bào/mL), loại nếp (nếp Thái, nếp Thái thơm, nếp Long An dẻo, nếp Cái hoa vàng, nếp lứt), tỷ lệ nấm và nếp (40:60, 50:50, 60:40 w/w) và nồng độ muối (1 %, 2 %, và 3 % w/w). Kết quả cho thấy chủng vi khuẩn HCGT31 có khả năng sinh acid lactic cao nhất sau 2 ngày lên men với hàm lượng 19,05 g/L. Điều kiện lên men nấm sò vua tốt nhất là ở nhiệt độ 37 °C và mật độ giống 107 tế bào/g, sử dụng nếp Thái thơm với tỷ lệ nấm và nếp là 50:50 w/w và nồng độ muối là 1% w/w. Sản phẩm nem chua sau 24 giờ lên men có hàm lượng acid là 7,43 g/L, pH = 4,44 và điểm đánh giá cảm quan là 15,89/20 theo TCVN 3215:79.
DERMATOLOJİK BOZUKLUKLARIN TEDAVİSİNDE GÖZ HAREKETLERİYLE DUYARSIZLAŞTIRMA VE YENİDEN İŞLEMENİN (EMDR) KULLANIMI
Authors: Kaçmaz Hilal Nur , İlerisoy Melike
Published: December 2024

Stres ve kaygı benzeri yaşantıların dermatolojik bozuklukların etiyolojisinde yer alan önemli faktörler olması nedeniyle bu rahatsızlıkların tedavisinde psikoterapötik müdahalelerin kullanımı giderek yaygınlaşmaktadır. Bu çalışmada EMDR yöntemi ile ele alınan deri yolma bozukluğuna ilişkin bir olgu sunumuna yer verilmiştir. Danışanın karşı koyamadığı deri yolma isteğinden dolayı yüz bölgesinde bulunan sivilceleri kaşıması, kaşıma sonrası oluşan yara ve morluklar sebebiyle danışmaya gelmesi üzerine sorun, EMDR odaklı dört oturum ve bir kontrol seansı olmak üzere toplam beş seansta ele alınmıştır. Her seansa ilişkin danışanın geribildirimleri ve kontrol seansındaki izleme bulguları çerçevesinde EMDR’nin danışanın deri yolma davranışının azalması ve kontrol altına alınmasında etkili olduğu, genel iyilik halinin artmasına yardımcı olduğu görülmüştür. Psikodermatolojik bir hastalık olan deri yolma bozukluğunun olası ruhsal faktörler açısından ele alınarak EMDR tekniğinin uygulandığı bir olgu çerçevesinde değerlendirilmesini amaçlayan bu çalışmanın multidisipliner tedavi yöntemlerinin geliştirilmesi bağlamında ilgili alana katkı sağlayacağı düşünülmektedir.
Digital pills and smart drug delivery: revolutionizing precision medicine- a review
Authors: Nagalakshmi S
Published: December 2024

The advent of digital pills and smart drug delivery systems marks a transformative era in precision medicine. This review explores the integration of digital technologies in pharmaceutical therapies, focusing on how these innovations enhance patient adherence, optimize therapeutic outcomes, and provide real-time data for healthcare providers. By leveraging advanced materials and microelectronics, digital pills have the potential to track ingestion patterns, monitor physiological responses, and personalize treatment regimens, facilitating a move away from one-size-fits-all approaches. We discuss the technological advancements driving this revolution, such as ingestible sensors, automated dosage dispensers, and mobile health applications. Additionally, we address the challenges and ethical considerations surrounding the use of digital pills in clinical practice, including data privacy, patient consent, and the implications for healthcare equity. This comprehensive review underscores the promise digital pills and smart drug delivery systems hold for improving patient outcomes and shaping the future of personalized medicine.
Green Cloud Technologies for SAP-driven Enterprises
Authors: Jampani Sridhar , Gudavalli Sunil , Ravi Vamsee Krishna , Goel Om , Jain Arpit , Kumar Lalit
Published: December 2024

Green Cloud Technologies are rapidly transforming the landscape of enterprise IT solutions, particularly for SAP-driven businesses. As organizations increasingly turn to cloud computing for its scalability, flexibility, and cost-efficiency, the environmental impact of traditional data centers has raised significant concerns. Green Cloud Technologies aim to address these concerns by leveraging sustainable practices, renewable energy sources, and energy-efficient infrastructures in cloud data centers. For SAP-driven enterprises, which rely on complex, resource-intensive business processes, adopting green cloud solutions offers a dual benefit: reducing operational costs while supporting corporate sustainability goals. This paper explores the role of Green Cloud Technologies in SAP environments, highlighting the integration of energy-efficient systems, eco-friendly hardware, and sustainable cloud services. It also examines best practices for SAP-driven enterprises to optimize resource usage, minimize carbon footprints, and align with global environmental standards. By adopting Green Cloud solutions, businesses not only contribute to environmental conservation but also enhance their competitiveness by aligning with increasingly stringent regulatory requirements and stakeholder expectations for sustainability.
Tinospora cordifolia (Giloy): A Review of the Various Pharmacological Pathways of a Highly Potential Medicinal Ayurveda Plant
Authors: Bhardwaj Amartya Kumar , Sahani Vandana , Patil Shivanand M.
Published: December 2024

Tinospora cordifolia, often known as "Amrita" or "Guduchi," is a medication that played a significant role in Indian systems of medicine (ISM) and has been utilised in the treatment of many ailments since the beginning of time. The term "guduchi" comes from the Sanskrit language and translates to "which protects the body from diseases." There is another name for this herb, and that name is "Amrita," which is a reference to the celestial elixir that is described in Hindu mythology. The medication is a well-known Indian bitter that is used for a variety of conditions, including fevers, diabetes, dyspepsia, jaundice, urinary issues, skin illnesses, and frequent diarrhoea and dysentery. Furthermore, it has been demonstrated to be effective in the treatment of cardiovascular disorders, leprosy, helminthiasis, and rheumatoid arthritis syndrome. In addition to being a significant medicine, it is utilised in a variety of preparations, including Satva, Ghrita, Tail, Swarasa, and all of these. An examination of the Charaka Samhita, the Sushruta Samhita, the Ashtanga Hridaya, the Ashtanga Sangraha, the Bhavprakash Nighantu, the Raj Nighantu, the Dhanvantari Nighantu, the Shaligrama Nighantu, the Priya Nighantu, the Kaiydev Nighantu, the Madanpal Nighantu, and the Shodhal Nighantu, as well as the internet and contemporary medical literature, have all been examined for this review article. There was a widespread recognition that the Tinospora cordifolia plant possessed high degrees of medicinal, therapeutic, curative, healing, and alleviating properties. By virtue of its anti-toxic, anti-inflammatory, anti-pyretic, and anti-oxidant qualities, guduchi possesses a significant potential for therapeutic application. Moreover, there is no evidence to suggest that Guduchi contains any hazardous substances or has any adverse effects, which further demonstrates that it is safe to use. Concluding remarks: The medicinal characteristics of the plant Tinospora cordifolia (Giloy) have been confirmed by the studies that were presented in this review. These studies focus on the therapeutic and safety features of the herb, and they demonstrate that it can prevent a variety of diseases or abnormalities by naturally boosting immunity in human bodies.
Review on Medicinal Herbs in the Treatment of Gout
Authors: Kumar Munna , Kori Arti , Patil Shivanand M.
Published: December 2024

Joint urate crystals are the hallmark of the inflammatory condition known as gout. Acute gout is characterised by the abrupt development of swelling and pain that begins in the greater toe. This condition is linked to high levels of uric acid in the blood, which can occur when the kidneys do not excrete enough of the acid or when the body produces too much uric acid. Allopurinol, which inhibits the enzyme xanthine oxidase and hence lowers blood uric acid levels, is the mainstay of conventional gout treatment in contemporary medicine. Pain and inflammation can be managed with the help of nonsteroidal anti-inflammatory drugs (NSAIDs). It has also been seen that non-pharmacological approaches, such as dietary improvements, can improve patients' situations. Many people believe that herbal treatments are safer and more effective than conventional pharmaceuticals, especially when it comes to patient adherence and the potential for adverse effects. Celery and parsley, when used together, have demonstrated effects comparable to those of allopurinol. This article's goal is to provide a summary of allopurinol's herbal substitutes.
Review on Ketoprofen (Anti-Inflammatory Drug)
Authors: Kumar Bhupendra , Sahani Vandana , Patil Shivanand
Published: December 2024

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely utilized for its analgesic, anti-inflammatory, and antipyretic properties. This review article examines ketoprofen's pharmacological profile, efficacy, and therapeutic applications, particularly in the management of acute and chronic pain, including dysmenorrhea, osteoarthritis, and rheumatoid arthritis. Ketoprofen exerts its effect by inhibiting the cyclooxygenase (COX) enzymes, COX-1 and COX- 2, reducing the synthesis of prostaglandins responsible for pain and inflammation. Various formulations of ketoprofen are available, including oral tablets, topical gels, suppositories, and injectables, each tailored to specific clinical needs and patient preferences. Recent advancements in topical and extended-release formulations have improved patient adherence and minimized gastrointestinal side effects traditionally associated with NSAIDs. However, ketoprofen remains contraindicated in patients with certain cardiovascular, renal, and gastrointestinal conditions, underscoring the need for careful patient selection and dosage adjustment. This review highlights ketoprofen's clinical efficacy, safety profile, and evolving therapeutic applications, providing insight into its role within the broader scope of pain management strategies.
Review on Allopurinol in the Treatment of Gout
Authors: Aryan  , Sahani Vandana , Patil Shivanand M.
Published: December 2024

Gout and pain are synonymous, and a study in this issue of the BJP reports a novel anti-nociceptive effect of allopurinol, the drug most commonly used to treat gout. Allopurinol works by inhibiting xanthine oxidase (XO), the enzyme responsible for converting hypoxanthine to uric acid which is deposited as crystals in the joints of gout sufferers. Hypoxanthine is a metabolite of, and a possible precursor to, adenosine.  find that acute inhibition of XO with allopurinol produces a modest adenosine A1 receptor-mediated anti-nociceptive effect in common tests of chemical and thermal nociception in mice. A concomitant increase in cerebrospinal fluid levels of adenosine supports their hypothesis that inhibiting XO increases adenosine levels via salvage from hypoxanthine. Elevating endogenous adenosine levels by inhibiting metabolism is a well-established strategy for producing anti-nociception in many preclinical models, but inhibiting XO is likely to be particularly beneficial in some chronic pain states because of the pro-nociceptive reactive oxygen species that are produced by XO activity. Thus, allopurinol may have unexpected benefits in pain associated with chronic inflammation, diabetes and vascular dysfunction.
Optimizing IT Infrastructure for Business Continuity
Authors: Annam Sri Nikhil
Published: December 2024

IT infrastructure is a critical value to ensuring business continuity. It describes the means to maximize IT infrastructure for both resilience, scalability, security, and cost-effectiveness. Based on the current adoption trends in hybrid clouds, edge computing, and automation, the research outlines approaches for improving disaster recovery, fault-tolerant systems, and emerging technologies in AI and IoT. It gives concrete recommendations and also emphasizes performance metrics for sustainable IT infrastructure planning. The study relies on the latest technical information, as well as tables and code snippets to illustrate optimization methods.
Advancements in Biodegradable Materials: Impacts on Soil and Water Quality
Authors: Singh Hanumant
Published: December 2024

This study explores the degradation rates of various biodegradable materials and their impact on soil and water quality under both laboratory and field conditions. The materials examined include polylactic acid (PLA), polyhydroxyalkanoates (PHA), starch-based plastics, cellulose-based films, and compostable plastics. Results show significant variation in degradation rates, with cellulose-based films and starch-based plastics exhibiting the fastest degradation, while PLA degraded the slowest, particularly in aquatic environments. In soil, the degradation of biodegradable materials led to increased microbial activity and changes in nutrient levels, particularly nitrogen and phosphorus. However, concerns about nutrient pollution and soil imbalances emerged, particularly with the faster-degrading materials. In aquatic environments, the impact of biodegradable materials on water quality was less pronounced, with only slight changes in dissolved oxygen, nitrate, and phosphate levels. The study emphasizes the need for careful management and monitoring of biodegradable materials to prevent unintended environmental consequences, such as nutrient pollution or microbial imbalances. These findings contribute to the growing understanding of biodegradable materials' real-world performance and their potential to serve as a more sustainable alternative to conventional plastics, while also highlighting the challenges associated with their environmental impact.
Endocrinology and Autoimmune Diabetes
Authors: Majid Abd Ulameer Alhumairi Rasha , I K Aljuboori Shaymaa , Aso Taher Tara , Tariq Sabaar Zeena
Published: December 2024

Therapists within the constantly evolving area of endocrinology, including diabetes treatment in especially, have to rapidly incorporate novel knowledge into their daily practice. Endocrinology is a field of medical or physiology that examines the endocrine system, including its hormonal substances, or disorders. It is structured in an interesting, individualized manner. A frequent endocrine condition that impacts the amount of sugar in the blood called diabetes. There are some linked facts regarding endocrinology as well as diabetes: this style gives readers an additional accessible or targeted method to quickly answer particular medical issues by listing them. This extensive written content, which encompasses the most prevalent medical challenges in endocrinology or diabetes, has been created by a famous, worldwide panel of specialists. Endocrinologists, diabetic specialists, internal health medical professionals, general doctors, fellows, or resident would all find it very interesting.
Role of SAP Order Management in Managing Backorders in High-Tech Industries
Authors: Yadav Nagender , Prasad Rohan Viswanatha , Kyadasu Rajkumar , Goel Om , Jain Arpit , Vashishtha Sangeet
Published: December 2024

Effective order management is critical in the high-tech industry, where rapid innovation, fluctuating demand, and global supply chain complexities create unique challenges. SAP Order Management emerges as a robust solution for addressing these challenges, particularly in managing backorders. Backorders, a common issue in high-tech industries, can significantly impact customer satisfaction, operational efficiency, and profitability. This paper explores the role of SAP Order Management in mitigating backorder risks and streamlining the fulfillment process.
SAP’s comprehensive tools offer real-time visibility into inventory, orders, and demand forecasts, enabling companies to prioritize high-value orders, reallocate resources effectively, and minimize delays. Its integration with advanced analytics allows businesses to identify root causes of backorders, such as supply chain disruptions or inaccurate demand planning. Furthermore, SAP’s automation capabilities facilitate efficient workflows by automating order prioritization and fulfillment processes, reducing manual errors and operational bottlenecks.
In high-tech industries, where product lifecycles are short and customer expectations are high, the ability to manage backorders effectively is vital. SAP Order Management supports seamless collaboration across departments, ensuring that sales, supply chain, and production teams work cohesively to meet demand. This study highlights case examples where SAP Order Management has improved order accuracy, reduced backorder rates, and enhanced customer experiences in high-tech firms.
Ultimately, SAP Order Management proves to be a transformative tool for high-tech companies, enabling them to address backorder challenges proactively and maintain a competitive edge in a fast-paced market.
Trends in the Use of Animated Teaching Media in Learning Islamic Religious Education: A Review of Bibliometric Analysis
Authors: Huda Ali Anhar Syi’bul , Anwar Saepul
Published: December 2024

IRE learning can be meaningful in various ways, one of which is applying animation media in the learning process, but not only at the level of application, it needs further development, namely through what renewable topics can be developed in the future. Based on this background, this research aims to examine the development of animation media in IRE learning over the past 10 years and future opportunities. The research design uses a qualitative approach with bibliometric research methods through the help of the publish or perish (PoP) application and VOSViewer and the data source comes from the Crossref database with a sample of 1000 published articles which are then filtered back to 988 published articles, while the analysis used is descriptive. The results revealed that the development of research on the topic of animated media in IRE learning over the past 10 years (2014-2024) experienced an increasing condition with a peak in 2022 with 196 publications. Productive researchers on the topic include Ulfia Ustina, Abdullah Arief Cholil, and Ali Bowo Tjahjono from UNISSULA Semarang University with 4 published articles. Some topics that can be developed in the future include efficiency, mean, line, issue, Islamic, national education, view, faculty miles, cycle, percentage, data display, element, idea, multiculturalism, Allah swt, Islamic education, religion, religion, covid pandemic, public SMP, model implementation, students, technology, role, data source, and data reduction.
Development of Manipulative Media “Brusil Board” for Curved Side Space
Authors: Mutina Mutina , Qohar Abd.
Published: December 2024

Curved-sided space is a math material taught at the junior high school level. This material is considered difficult for students because there are so many formulas that must be understood as well as memorized. Therefore, learning media is needed that can help the above problems. This research aims to produce a valid and practical Brusil Board manipulative media used by teachers and students in learning activities for the volume of curved-sided space. The type of research used is Research and Development with the ADIIE model which consists of 5 stages including analysis, design, development, implementation, and evaluation stage. The test subjects consisted of ten students of the master of mathematics education. The research instruments used include validation sheets and student response questionnaires. The results show that the total average percentage of the validation test was 84.25% from the experts and the total average percentage of the practicality test was 90% from the test subjects. So, it can be concluded that the Brusil Board manipulative media is declared very valid and practical to be used by teachers and students in learning so that the concept of volume of curved-sided space can be well constructed in students' knowledge.
The Future Impact of Artificial Intelligence according to the Opinions of Hungarian and Turkish Youth in the Sight of a National Competitveness
Authors: Revak Bernadett , Csiszarik-Kocsir Agnes
Published: December 2024

: The 21st century has brought many changes to our lives. Digitalisation has gained unprecedented momentum, leading to a series of innovations in the field. Artificial intelligence was in its infancy at the beginning of the millennium. Research into artificial intelligence as given a boost by the rise in computer power and the ubiquity of the internet, which opened up new avenues for research. The real breakthrough for artificial intelligence came in the 2010s, when deep learning and the use of neural networks became widespread and generalised. Opinions on the future of AI are very mixed. One thing is certain: its rapid future development will transform the labour market, education, but the production and manufacturing sectors will be no exception. Artificial intelligence applications are capable of autonomous decision-making and creative problem solving, which will make people increasingly comfortable. Today's young people will certainly learn, work and live in an environment that will be significantly influenced by AI applications. That is why we consider it very important to get the views of the young, currently school-age generation on this topic, in order to prepare them adequately for the challenges and expectations. To be able to cope in a world where artificial intelligence is at work, young people need to have the right digital skills and competences, which the education system must provide them with. Our study aims to highlight the differences between Hungarian and Turkish young people, and to show the development directions and gaps for future success.
Financial Literacy and Basic Concepts in the 21st Century
Authors: Csiszarik Viktor
Published: December 2024

Today's rapidly changing world has opened a new chapter in human history. New innovations and innovations in finance and in all aspects of life have completely rewritten the scope and nature of the skills and competences needed to succeed in the economy. New players have emerged in the financial world, introducing new products. This new body of knowledge is difficult for each generation, especially the older ones, to adapt to. New products, new payment instruments and new forms of savings have emerged in recent years to which the older generation is finding it difficult to adapt. The aim of my study is to present, on the basis of the results of a questionnaire survey carried out in Hungary, the new solutions and concepts that are having a breakthrough effect in the field of finance. I would also like to discuss the new payment solutions, payment instruments and other general concepts from the point of view of their use, which will be decisive in the future financial world.
Simulations of Public Debt
Authors: Kara Ahmet
Published: December 2024

Public debt trajectories are multidimensionally interconnected with the other processes in the economy, and as such, they had better be analyzed within a system framework that takes into account the public-debt related interrelations and feedback loops which could involve many macroeconomic as well as microeconomic factors (including the non-economic ones) that could have significant influences on the trajectories in question. In this paper, we develop a simple system-based framework where we begin to exemplify the interrelations and causal connections embodied within the system. By explicating such interrelations, we will account for the underlying interconnectivity that, together with other factors, give rise to the formation of the debt trajectories which could span over a number of years. Once the underlying interconnectivity and the relevant factors are specified, we can construct a system dynamics model so as to simulate the debt trajectories under conditions that are of practical significance to policy makers. Simulating the trajectories, with a reasonable degree of accuracy, opens the doors to the optimal management of debt processes. Correctly predicting the debt figures at different points in time enables the policy makers to design and implement policies so as to influence/control the trajectory to achieve the debt-related objectives. An example of the policy of this kind will be provided in the text.
The Transition Policy from Kindergarten to Primary Education
Authors: Andriana Chusnia , Burhanuddin Burhanuddin , Sobri Ahmad Yusuf
Published: December 2024

This research aims to comprehensively investigate the implementation of the kindergarten to primary school (PAUD-SD) transition policy in Tumpang District. The research method employed is qualitative with a descriptive approach. Data collection involved interviews, document gathering using recording tools and notebooks, along with references from relevant literature. Data analysis was conducted using the qualitative analysis method by Miles and Huberman, involving data reduction, data presentation, and data verification. To validate data authenticity, a triangulation approach was utilized, engaging various methods and diverse data sources. The research findings indicate that the implementation of the PAUD-SD policy in Tumpang District has been initiated through socialization by the district's education coordinator. This led to an agreement to establish PAUD-SD communication forums in each village, involving collaboration between Kindergarten and Primary School teachers to plan joint programs such as parenting for new student's parents, exchange visits between Primary School and Kindergarten, and a decision not to conduct mid-term or final evaluations for firstgrade students for the initial 6 months. However, the formal work program is awaiting guidance from the Malang Regency Education Office. The impact of this research underscores recommendations for promptly taking concrete actions to ensure that the establishment of the PAUD-SD transition forums in Tumpang District effectively achieves its objectives.
Boosting Learning Interest in Phase F Marketing Students with Eko and Nomi Comics: Teaching Scarcity and Basic Economic Problems
Authors: Wulandari Ela , Utomo Sugeng Hadi , Rokhmani Lisa , Handayani Sri
Published: December 2024

Media are an important part of learning process. Choosing and using the right media should be done carefully to ensure that learning goals are met successfully. This research aimed to develop an engaging and effective comic-based learning media to enhance students' interest in learning Economics and General Administration, particularly on the topic of scarcity and basic economic problems for Phase F of Vocational High School (SMK) with Marketing Expertise Competency. The method used was Research and Development (R&D) with a Borg and Gall. The developed Eko and Nomi comic was designed using Pixton and Canva applications to effectively integrate visual and textual elements. This research aimed to determine: (1) the feasibility of digital comic-based learning media and (2) the practicality of the media was analyzed based on the results of the questionnaire filled out by the students. The subjects of this research were 66 students in the Phase F Marketing program and 3 validators. Data collection was conducted using observation, interviews, and questionnaires. The instruments used included a product feasibility questionnaire and a student response questionnaire. The results of the research showed that the feasibility tests by media and content experts, scores of 74.5% categorized as valid and 87.87% categorized as very valid were obtained, respectively. Thus, the average feasibility test score by experts was 81.18%, categorized as very valid. The practicality test was derived from the students' responses, with an average score of 80.09%, categorized as practical.
On the Reliability of Black-Market Exchange Rate: Evidence from Algeria
Authors: Bouteldja Abdelnacer , Sifeeddine Benbekhti
Published: December 2024

The existence of a well-defined and stable money demand function is an essential condition for conducting of an effective monetary policy. In Algeria, as is the case for most of developing countries, excessive control on foreign exchange leads to the emergence of black-market exchange rate. As a consequence, two exchange rates (official and black) coexist and operate simultaneously. The gap between the two rates has widened since the adoption of the structural adjustment program in 1994. Despite its negative impact on Algerian economy, this market has not, so far, attracted attention of researchers. Using an autoregressive distributed lag technique for a set of quarterly data going from 1990Q1- 2021Q4, we aim to investigate the effect of black-market exchange rate on the demand for money. Our results provide further evidence for the inclusion of the black rather than the official rate when drawing a monetary policy.
Strengthening Algerian Economic Enterprise Environmental Competitiveness Analysis: The Case of Algeria Telecom in Laghouat
Authors: Oukacha Larabi
Published: December 2024

This study aimes to identify the role of environmental analysis in strengthening the competitiveness of Algeria Telecom, the operational agency in Laghouat. A descriptive analytical methodology was used to analyze the mentioned institution data, and a questionnaire was used as the main tool for collecting the analyzed data using the SPSS statistical software package. A number of results are reached, the most important of which is the existence of a statistically significant positive relationship between the contribution of environmental analysis and the strengthening of competitiveness in Algeria Telecom. In the light of these findings, the study made a set of recommendations and proposals on the subject. It can be concluded that this study enhances the importance of environmental analysis in strengthening the competitiveness of enterprises, especially in the telecommunications sector. The findings and recommendations provided may be important in guiding policies and actions for similar organizations in strengthening enterprises’s competitiveness.
Pengaruh Kualitas Pelayanan Dan Harga Terhadap Kepuasan Konsumen Pengguna Bus Di Kota Serang
Authors: IRWAN IRWAN ZAINI , Handoko Pryo
Published: December 2024

This research was conducted to find out whether many people still use bus transportation services in the city of Serang, this is considering the rapid development of railway companies in Indonesia, including in the city of Serang. The aim of this research is to determine the influence service quality and price on consumer satisfaction of bus users in Serang City, as well as to determine the influence of service quality and price simultaneously on onsumer satisfaction of bus users in Serang City. This research uses quantitative methods with regression analysis techniques. The population of this research is bus users in the city of Serang. The research sample used random sampling statistics with a research sample of 55 Serang city bus user. Data collection was carried out by distributing questionnaires. Data was analyzed using the SPSS application. The research results show that service quality has a positive effect on consumer satisfaction and price has a positive effect on consumer satisfaction. The magnitude of the influence of the two independent variables on the dependent can be seen from the R Square value, is 73.6%, While the remainder is influenced by other variables at 26.4%.
PENGARUH KEPEMIMPINAN TRANSFORMASIONAL DAN BUDAYA ORGANISASI TERHADAP KINERJA PEGAWAI DI KANTOR DPR RI KOMISI X
Authors: Rifky Rifky Hermiansyah , Sondjaya Trisna
Published: December 2024

DPR RI dan memiliki tanggung jawab dalam mengurus ketenagakerjaan, kesehatan, dan kesejahteraan sosial. terkait dengan prestasi kerja pegawai yang bekerja pada Kantor DPR RI komisi X di Jakarta yang diperoleh dari hasil pengamatan mengalami penurunan yang disebabkan oleh beberapa faktor yang dilihat dari kepemimpinan transformasional di mana menunjukkan pimpinan dinilai masih kurang dalam menginspirasi pegawai lain untuk pencapaian tujuanPendekatan dalam penelitian ini adalah pendekatan kuantitatif. Menurut Sugiyono (2020:16), metode penelitian kuantitatif dapat diartikan sebagai metode penelitian yang berlandaskan pada filsafat positivisme, digunakan untuk meneliti pada populasi atau sampel tertentu, pengumpulan data menggunakan instrumen penelitian, analisis data bersifat kuantitatif/statistik, dengan tujuan untuk menguji hipotesis yang telah ditetapkanPengujian construct validity melalui analisis faktor terhadap instrumen penelitian ditujukan untuk mengukur pengaruh Kepemimpinan Transformasional dan Budaya Organisasi terhadap Kinerja Pegawai Siswa Komisi X DPR RI. Variabel yang digunakan dalam penelitian ini adalah Kepemimpinan Transformasional. skor total yang merupakan jumlah seluruh skor butir menggunakan rumus korelasi Product Moment dengan alpha 5%. Kepemimpinan Transformasional terhadap Kinerja Pegawai di DPR RI Komisi X Hasil penelitian menyatakan bahwa Kepemimpinan Transformasional di DPR RI Komisi X berdasarkan perhitungan dengan SPSS menunjukkan terdapat hubungan Kepemimpinan Transformasional dengan Kinerja Pegawai sebesar 0.146. Budaya Organisasi terhadap Kinerja Pegawaiberdasarkan perhitungan SPSS dapat nilai korelasi sebesar 0,332 . Minat Berwirausaha Dari hasil pengolahan data penelitian dengan bantuan perhitungan SPSS 27.0.1.
PERANAN BADAN USAHA MILIK DESA (BUMDes) DALAM MENINGKATKAN PEREKONOMIAN MASYARAKAT DESA (Studi Kasus Pada Bumdes Cibokormas Desa Cibarani Kecamatan Cisata Kabupaten Pandeglang)
Authors: Sujana Endang , Jumanah
Published: December 2024

Badan Usaha Milik Desa (BUMDes) adalah suatu lembaga usaha desa yang di kelola oleh masyakat dan pemerintah desa dalam upaya memperkuat perekonomian desa yang dibentuk berdasarkan kebutuhan masyarakat dan potensi desa. Namun nyatanya terbentuknya BUMDes di Desa Cibarani belum mampu meningkatkan perekonomian masyarakat Desa Cibarani Kecamatan Cisata. Terdapat berbagai hambatan yang dialami dalam pengelolaan BUMDes.
Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus yang mengungkap permasalahan pada sistem pengelolaan BUMDes di Desa Cibarani Kecamatan Cisata. Untuk mempermudah dalam menganalisi permasalahan maka dianalisis dengan menggunakan teori mengenai sistem pengelolaan BUMDes berdasarkan hasil penelitian dari Pusat Kajian Dinamika Sistem Pembangunan (PKSP) Universitas Brawijaya (2017: 13).
Adapun hasil penelitian bahwa ditemukan peranan BUMDes dalam meningkatkan perekonomian masyarakat desa belum optimal serta BUMDes Cibokormas belum sepenuhnya menjalankan prinsip dalam pengelolaan BUMDes, terdapat kendala atau hambatan salah satunya yaitu partisipasi masyarakat yang rendah, tingkat kepercayaan rendah, SDM yang kurang berkualitas, serta modal usaha yang minim. Berbagai upaya sudah dilakukan namun belum mampu membawa perkembangan bisni dan belum mampu memperkuat perekonomian Desa Cibarani.
 
Kata kunci : Peranan, BUMDes, Ekonomi masyarakat.