bluuebunny/crossref_metadata_2025 huggingface dataset:
Developments in a surficial stratigraphic framework for 3D geological modelling
Authors: Sharpe D R , Bajc A F , Burt A K , Logan C , Mulligan R P
M , Russell H A J , Todd B
Published: March 2017

Work is ongoing on the development of a framework for a Southern Ontario regional 3D surficial geological model. The focus in 2016-17 has been on data capture and web enabling for online viewing/download. This work builds on and complements the extensive database
of subsurface information acquired over the last 15 years by the Ontario Geological Survey (OGS) as part of its surficial 3D mapping initiative. Recent coring programs in Simcoe County and the Niagara Peninsula have resulted in cores to bedrock being retrieved across much of the 'Golden horseshoe'.
Continuous coring provided ground-truthing for over 100 line-kms of reflection seismic data recently collected in these areas. Legacy and archival datasets are also being added to complement the cored-borehole dataset. The 3D model is built on a provincial digital elevation model supplemented for
Great Lakes by NOAA bathymetric data and for smaller lakes Canadian hydrographic field sheets (e.g., navigable waterways, Trent - Severn). Geological interpretations have been added from legacy high-resolution reflection seismic profiles in Lake Ontario (bedrock topographic elevation). The
stratigraphic framework is additionally being enhanced by the capture of section descriptions and borehole logs from past OGS surficial mapping projects, integrated into a PostgreSQL database. Stratigraphic classification of Provincial Groundwater Monitoring Wells and data-mining from Source Water
Protection technical reports will also inform the model as will data from the MOECC Water Well enhancement project.
In addition, downhole geophysical and geochemistry frameworks will assist with stratigraphic classification. Downhole geophysical data can reduce reliance on continuous-core data for stratigraphic studies once adequate work has established an index 'fingerprint' for stratigraphic units.
Consolidation of combined stratigraphic data in a PostgreSQL database supports serving this information online via Groundwater Information Network (GIN). GIN works in concert with parallel MOECC initiatives to support a distributed database framework for groundwater geoscience in
Ontario.
DESIGN GUIDELINES FOR AIR CONDITIONING SYSTEMS FOR OFF-ROAD OPERATOR ENCLOSURES
Authors:   HFTC6, Operator Accommodation
Published: March 2017

The purpose of this document is to establish air conditioning design guidelines that will apply to most systems rather than the specific design of any particular system. Operating conditions and characteristics of the equipment will determine the design of any successful system, and since these characteristics and conditions vary greatly from one application to another, the designer must determine the goals expected to be reached under the conditions encountered. To determine the capacity of such items as blowers, condenser fans, condenser coils, evaporator coils, filters, compressors, etc., will require the adherence to several guidelines, some of which are outlined in the following paragraphs.
Unibody Weld Quality Testing
Authors:   Motor Vehicle Council
Published: March 2017

The most important aspect of structural unibody repair is the correct application of Gas Metal Arc Welding, or G.M.A.W (formerly called Metallic Inert Gas, M.I.G) welding. It is the intent of the SAE Recommended Practice to inform the body repairman on how to evaluate his welds and check if the welder is properly adjusted. By doing this, he can improve the quality of his structural repairs and develop consistent welds.
Space-based NOx emission estimates over remote regions improved in DECSO
Authors: Ding Jieying , van der A Ronald Johannes , Mijling Bas , Levelt Pieternel Felicitas
Published: March 2017

Abstract. We improve the emission estimate algorithm DECSO (Daily Emission estimates Constrained by Satellite Observations) to better detect NOx emissions over remote areas. The new version is referred to as DECSO v5. The error covariance of the sensitivity of NO2 column observations to gridded NOx emissions has been better characterized. This reduces the background noise of emission estimates by a factor of 10. An emission update constraint has been added to avoid unrealistic day-to-day fluctuations of emissions. We estimate total NOx emissions, which include biogenic emissions that often drive the seasonal cycle of the NOx emissions. We demonstrate the improvements implemented in DECSO v5 for the domain of East Asia in the year 2012 and 2013. The emissions derived by DECSO v5 are in good agreement with other inventories like MIX. In addition, the improved algorithm is able to better capture the seasonality of NOx emissions and for the first time it reveals ship tracks near the Chinese coasts that are otherwise hidden by the outflow of NO2 from the Chinese mainland. The precision of monthly emissions derived by DECSO v5 for each grid cell is about 20 %.
Characterization of the OCO-2 instrument line shape functions using on-orbit solar measurements
Authors: Sun Kang , Liu Xiong , Nowlan Caroline R. , Cai Zhaonan , Chance Kelly , Frankenberg Christian , Lee Richard A. M. , Pollock Randy , Rosenberg Robert , Crisp David
Published: March 2017

Abstract. Accurately characterizing the instrument line shape (ILS) of the Orbiting Carbon Observatory-2 (OCO-2) is challenging and highly important due to its high spectral resolution and requirement for retrieval accuracy (0. 25 %) compared to previous spaceborne grating spectrometers. On-orbit ILS functions for all three bands of the OCO-2 instrument have been derived using its frequent solar measurements and high-resolution solar reference spectra. The solar reference spectrum generated from the 2016 version of the Total Carbon Column Observing Network (TCCON) solar line list shows significant improvements in the fitting residual compared to the solar reference spectrum currently used in the version 7 Level 2 algorithm in the O2 A band. The analytical functions used to represent the ILS of previous grating spectrometers are found to be inadequate for the OCO-2 ILS. Particularly, the hybrid Gaussian and super-Gaussian functions may introduce spurious variations, up to 5 % of the ILS width, depending on the spectral sampling position, when there is a spectral undersampling. Fitting a homogeneous stretch of the preflight ILS together with the relative widening of the wings of the ILS is insensitive to the sampling grid position and accurately captures the variation of ILS in the O2 A band between decontamination events. These temporal changes of ILS may explain the spurious signals observed in the solar-induced fluorescence retrieval in barren areas.
Optimization of wind plant layouts using an adjoint approach
Authors: King Ryan N. , Dykes Katherine , Graf Peter , Hamlington Peter E.
Published: March 2017

Abstract. Using adjoint optimization and three-dimensional steady-state Reynolds-averaged Navier–Stokes (RANS) simulations, we present a new gradient-based approach for optimally siting wind turbines within utility-scale wind plants. By solving the adjoint equations of the flow model, the gradients needed for optimization are found at a cost that is independent of the number of control variables, thereby permitting optimization of large wind plants with many turbine locations. Moreover, compared to the common approach of superimposing prescribed wake deficits onto linearized flow models, the computational efficiency of the adjoint approach allows the use of higher-fidelity RANS flow models which can capture nonlinear turbulent flow physics within a wind plant. The steady-state RANS flow model is implemented in the Python finite-element package FEniCS and the derivation and solution of the discrete adjoint equations are automated within the dolfin-adjoint framework. Gradient-based optimization of wind turbine locations is demonstrated for idealized test cases that reveal new optimization heuristics such as rotational symmetry, local speedups, and nonlinear wake curvature effects. Layout optimization is also demonstrated on more complex wind rose shapes, including a full annual energy production (AEP) layout optimization over 36 inflow directions and 5 wind speed bins.
Applying ANP in Establishing a Decision-Making Model for the Destination Selection of Large-scale Exhibitions
Authors: Wu Wen-Tsung , Chen Chie-Bein
Published: March 2017

This study investigates the decision-making issues in the selection of destinations for large-scale exhibitions by the cultural and creative industry. We use the Rubber Duck China Tour by the Dutch artist Florentijn Hofman as an example and adopt the analytic network process technique to evaluate destination options for the exhibition, as well as to explore the impacts of the evaluation of destination feasibilities on exhibition investment. The results show that power, a high benefit-cost ratio, first-tier cities, integration with local communities, and a rich and interesting theme are the top five factors that curators should consider when planning exhibitions. Considering the priority among cities of various tiers, first-tier cities are the most favorable, followed by fourth-tier, third-tier, and second-tier cities. The decision-making model provides curators with a reliable reference for selecting destinations for future exhibitions.
Nebulized Adrenaline in the Postoperative Management of Brachycephalic Obstructive Airway Syndrome in a Pug
Authors: Ellis Jenny , Leece Elizabeth Ann
Published: March 2017

Brachycephalic obstructive airway syndrome is a common problem in certain breeds, and may necessitate surgical procedures, such as rhinoplasty, palatoplasty, laryngeal sacculectomy, and/or arytenoid laryngoplasty, to improve the quality of life. However, laryngeal edema may necessitate the use of temporary tracheostomy tubes postoperatively to maintain a patent airway. This case demonstrates that administration of nebulized adrenaline in the immediate postoperative period where upper airway obstruction is life threatening can be used to reduce edema, therefore avoiding the need for tracheostomy.
Breed-Specific Vertebral Heart Scale for the Dachshund
Authors: Birks Ryan , Fine Deborah M. , Leach Stacey B. , Clay Sarah E. , Eason Bryan D. , Britt Lisa G. , Lamb Kenneth E.
Published: March 2017

The objectives of this study were to determine a breed-specific vertebral heart scale (VHS) range for the dachshund and compare results to the established reference range of 9.7 ± 0.5, calculate inter-observer variability, and correlate VHS with echocardiography. Fifty-one normal dachshunds had radiographs and an echocardiogram performed. Five observers measured VHS to the nearest 0.25 vertebra. The data was analyzed using one-way analysis of variance, Wilcoxon Rank Sum test, Mann-Whitney rank sum test, calculation of reference and confidence intervals, Spearman rank-order correlations, and generation of intra-class correlations and confidence intervals. P < .05 was considered significant. The median for right lateral VHS was significantly larger than left (10.3 [range 9.25–11.55] versus 10.1 [range, 8.7–11.31], p < .0001). VHS for females was significantly larger than for males (left: 10.56 [9.2–11.31] versus 9.74 [8.7–10.88] and right: 10.8 [9.5–11.55] versus 9.99 [9.25–10.8], p = .0002). Observer consistency was high with an intra-class correlation coefficient of 0.95. No significant correlation was found between left atrial echocardiographic parameters and VHS. Results indicate normal dachshunds have a median VHS above the published generic canine reference range, and VHS can be reliably performed by observers with varying degrees of clinical experience.
Safety of Benazepril in 400 Azotemic and 110 Non-Azotemic Client-Owned Cats (2001–2012)
Authors: Lavallee Jennifer O. , Norsworthy Gary D. , Huston Carla L. , Chew Dennis J.
Published: March 2017

This retrospective study examined cats after initiation of benazepril therapy to determine the frequency of systemic hypotension or elevations in serum creatinine and/or potassium. Medical records review identified azotemic and non-azotemic cats prescribed benazepril. Blood pressure was recorded at the first available time after initiation of therapy. No cats experienced documented systolic systemic hypotension (<90 mmHg). Serum creatinine, and potassium when available, were recorded at baseline and in time windows after initiation of treatment: 1–30 days and 31–60 days. Blood chemistry results were screened for hyperkalemia (≥6.0 mEq/L). During the first 2 mo after starting benazepril therapy, there was a low incidence (3.7%) and clinically insignificant magnitude of hyperkalemia. Serum creatinine increases of greater than 30% from baseline were noted. This change was found in 11.0% of cats during the first 30 days of therapy and in 13.7% of cats from days 31–60 after initiation of therapy. The long-term survival of the cats that had >30% increases in creatinine from baseline was not statistically different from the survival of those that did not experience these increases, which suggests this finding may not be a reason to discontinue therapy. Benazepril appeared safe in a heterogeneous population of cats.
Ecstatic Abundance: Queer Temporalities in LGBTQ Studies and Music Education
Authors: Gould Elizabeth
Published: March 2017

Attempts to normalize (some) variant sexualities assume that normativity leads at least to tolerance. Because it occurs in relationship to preestablished norms, normativity is achieved through assimilation. Judith Butler’s (1993) theory of performativity demonstrates this in terms of gender/sexuality by which the gendered/sexualized subject is produced as an effect of repetitions of coercive (heterosexual) norms that precede the subject. Operating within a temporal logic of norms first, the subject second, performativity cites the past, projecting heterosexual subjects into the future, leaving queer subjects nowhere, unless we resignify those norms for an assumed transgressive future. Queer subjects must go along to get along: to be normal, but “the trouble with normal” is that it obviates queer culture (Warner, 1999), bequeathing to queer subjects no past. In response to the double bind of no future and no past, I posit queer temporalities of LGBTQ studies and music education as saturated abundant presents in terms of Deleuzian becoming in the queer time of the infinitive: to become. Eliding the past and future, the infinitive is just before and just after. I argue LGBTQ studies, expressing a queer ethic of kinship, activates Sara Ahmed’s (2006) “refusal to inherit” the norms of lack, and asserts ecstatic abundance as an exuberant queer erotic. Using Philip Auslander’s (2004) performer-centered approach, I analyze Cris Williamson’s (1975) song, “Shooting Star” as ecstatic abundance, contingently constituting LGBTQ studies as unquenchable, inexhaustible, unruly.
The Role of the Passive Voice Mindset in Regulating Healthy Eating
Authors: Senay Ibrahim , Usak Muhammet , Acarturk Zeynep Ceren
Published: March 2017

Talking about eating in the passive, as opposed to the active voice, (e.g., The cake will be eaten vs. I will eat the cake) can lead people to see the act of eating to be triggered by the food to a greater extent, leading to the continuation of past eating habits. Depending on whether or not the past habits are healthy, the motivation for healthy eating may change as a result. In study 1, writing passive sentences increased the motivation for healthy eating to the extent that people reported eating healthy in the past. Moreover, in study 2 across 127 languages spoken in 94 countries, when the acted-upons of actions (e.g., the food in the act of eating) became relatively more salient in a language, people became more likely to act on cultural habits that may be relatively healthier, decreasing unhealthy eating. The results are important for understanding the perceived role of food in starting eating as it impacts healthy eating across cultures.
De one-tier board volgens de herziene Corporate Governance Code
Authors: Salemink T.
Published: March 2017

De one-tier board volgens de herziene Corporate Governance Code

De Corporate Governance Code 2008 is toegeschreven op vennootschappen met een two-tier board (dualistisch bestuurssysteem). Het biedt vennootschappen met een one-tier board (monistisch bestuurssysteem) volgens de Monitoring Commissie onvoldoende handvatten en behoeft om die reden herziening. Het is de vraag of de Commissie met de recente herziening van de Code voldoende in haar voornemen tot verduidelijking is geslaagd.
Gergithoides Schumacher, 1915 in Vietnam, with two new species, and taxonomic notes on the genus (Hemiptera: Fulgoromorpha: Issidae)
Authors: Constant Jérôme , Pham Hong-Thai
Published: March 2017

Two new species of the genus Gergithoides Schumacher, 1915 (Issinae, Hemisphaeriini), G. gnezdilovi sp. nov. from Bidoup-Nui Ba National Park in Central Vietnam and G. nui sp. nov. from Pia-Oac National Park in North Vietnam, are described. These are the only species of the genus formally recorded from Vietnam to date. Habitus, details and male genitalia are illustrated and a distribution map is provided. Four females representing three or four additional species, known from females only, are mentioned and illustrated. Taxonomic and biogeographical updates based on a thorough review of the literature are proposed and discussed for G. carinatifrons Schumacher, 1915, G. rugulosus (Melichar, 1906) and G. undulatus Wang & Che, 2003.
Hermes in the future
Authors: Bergenholtz Henning , Engberg Jan
Published: March 2017

No abstract.
Comprehensible legal texts - utopia or a question of wording? On processing rephrased German court decisions
Authors: Hansen Sandra , Dirksen Ralph , Küchler Martin , Kunz Kerstin , Neumann Stella
Published: March 2017

This paper presents a study on the comprehensibility of rephrased syntactic structures in German court decisions. While there are a number of studies using psycholinguistic methods to investigate the comprehensibility of original legal texts, we are not aware of any study looking into the effect resolving complex structures has on the comprehensibility. Our study combines three methodological steps. First, we analyse an annotated corpus of court decisions, press releases and newspaper reports on these decisions in order to detect those complex structures in the decisions which distinguish them from the other text types. Secondly, these structures are rephrased into two increasingly simple versions. Finally, all versions are subjected to a self paced reading experiment. The ﬁndings suggest that rephrasing greatly enhances the comprehensibility for the lay reader.
Phraseographie
Authors: Hallsteinsdóttir Erla
Published: March 2017

Multiword expressions – i.e. phraseological units – like idioms and collocations are one of the most interesting part of every language. In this article, I investigate phraseological units from a lexicographical point of view. I discuss the theoretical and methodological basis of phraseography as a discipline that includes aspects of lexicography, phraseology, corpus linguistics and theories of language learning. I demonstrate the importance of corpora as a source for the lexicographer and the use of corpus data. I also discuss the requirements for the lexicographical treatment of phraseological units by the compilation of a phraseological database for language learners in relation to their assumed needs that have already been described in detail.
Emery LeBlanc : le conteur oublié
Authors: Bourque Denis
Published: March 2017

Dans sonHistoire de la littérature acadienne, publiée en 1983, Marguerite Maillet faisait découvrir à ses lecteurs de nombreuses oeuvres appartenant au répertoire acadien sur lesquelles l’histoire littéraire était demeurée jusqu’alors à peu près silencieuse. Parmi celles-ci figurait un recueil de récits, publié par Emery LeBlanc en 1957, intituléLes entretiens du village, qu’elle considère comme« le meilleur livre publié durant cette période et le plus intéressant ».Reçu d’abord avec enthousiasme par les contemporains de l’auteur, ce livre a toutefois peu retenu l’attention de la critique, alors qu’en Acadie, il n’a pas encore d’institution littéraire. Malgré le fait qu’il ait suscité de l’intérêt lors de sa réédition en 1979 aux Éditions d’Acadie, il demeure de nos jours un ouvrage peu connu, voire méconnu. Le but de cet article est de le faire redécouvrir aux chercheurs et à ceux qui s’intéressent à la littérature acadienne et de lui restituer, autant qu’il se peut, la place qui lui revient dans l’histoire des lettres acadiennes. Un an avant la parution des premières oeuvres d’Antonine Maillet et de Ronald Després, cet ouvrage vient clore et compléter de façon remarquable le corpus d’oeuvres qui font partie de la littérature acadienne traditionnelle (1875–1957), dont il constitue une parfaite synthèse sur le plan historique, sociologique, géographique et ethnologique. Cet article se penche sur le contexte sociolittéraire dans lequel cet ouvrage se situe, sur la place d’Emery LeBlanc dans l’histoire des lettres acadiennes et sur les sources et les principales caractéristiques de ses récits.
La géographie des disparités économiques au sein des localités du Canada atlantique : une étude comparative au cours de la période 1981–2006
Authors: Simard Majella
Published: March 2017

En dépit de ses nombreux éléments de similitude liés notamment à la faiblesse de l’armature urbaine, à une économie fortement orientée vers la mise en valeur des ressources et à une démographie qui peine à se renouveler, le Canada atlantique se présente comme un milieu fort hétérogène. Cette diversité entraîne des niveaux différents de développement selon les endroits. Bien que, de façon générale, les disparités économiques aient eu tendance à s’atténuer au cours des 25 dernières années, il n’en demeure pas moins que plusieurs localités sont aux prises avec des problèmes aigus d’emploi et de faibles niveaux de revenu. Le but de cet article est de dégager l’évolution des disparités économiques au sein des quatre provinces atlantiques entre 1981 et 2006. L’analyse, qui porte sur les 752 subdivisions de recensement de ce territoire, est effectuée à partir de quatre variables clés dans l’étude des disparités. Celles-ci sont examinées en considérant diverses catégories de milieux, établies en fonction de leur taille démographique. Un indice composite conduit à la construction de typologies permettant de mettre en évidence différents niveaux d’évolution.
Adolescents’ experience of a rapid HIV self‐testing device in youth‐friendly clinic settings in Cape Town South Africa: a cross‐sectional community based usability study
Authors: Smith Philip , Wallace Melissa , Bekker Linda‐Gail
Published: March 2017

Introduction: Since HIV testing in South African adolescents and young adults is sub‐optimal, the objective of the current study was to investigate the feasibility and acceptability of an HIV rapid self‐testing device in adolescents and young people at the Desmond Tutu HIV Foundation Youth Centre and Mobile Clinic.

Methods: Self‐presenting adolescents and young adults were invited to participate in a study investigating the fidelity, usability and acceptability of the AtomoRapid HIV Rapid self‐testing device. Trained healthcare workers trained participants to use the device before the participant conducted the HIV self‐test with device usage instructions. The healthcare worker then conducted a questionnaire‐based survey to assess outcomes.

Results: Of the 224 enrolled participants between 16 and 24 years of age, 155 (69,2%) were female. Overall, fidelity was high; 216 (96,4%) participants correctly completed the test and correctly read and interpreted the HIV test result. There were eight (3,6%) user errors overall; six participants failed to prick their finger even though the lancet fired correctly. There were two user errors where participants failed to use the capillary tube correctly. Participants rated acceptability and usability highly, with debut testers giving significantly higher ratings for both. Younger participants gave significantly higher ratings of acceptability.

Conclusions: Adolescents and young adults found HIV self‐testing highly acceptable with the AtomoRapid and they used the device accurately. Further research should investigate how, where and when to deploy HIV self‐testing as a means to accompany existing strategies in reaching the UNAIDS goal to test 90% of all individuals worldwide.
Driving cancer evolution
Authors: Fitzgerald Devon M , Rosenberg Susan M
Published: March 2017

Tumor-growth-factor-beta signaling helps cancer cells to evolve and become resistant to drugs by down-regulating accurate DNA repair.
Photos of (no)thing: The becoming of data about sexuality at school
Authors: Allen Louisa
Published: March 2017

This paper asks, what ‘newness’ (Springgay & Zaliwska, 2015) does a new materialist feminist engagement with photos of ‘nothing’ produce for thinking about images as data in research about sexuality at school? Somewhat unusually, this paper takes as its focus – photos of what appear to be, nothing. These indecipherable photos were captured by student photo-diarists as part of research into the sexual cultures of schooling. Traditionally, these photos would not constitute data because they contain no identifiable people or objects, are blurry and were classified by photo-diarists as ‘mistakes’. This paper involves a revisiting of these images drawing on the work of Barad (2007), Hultman and Lenz Taguchi (2010) and MacLure (2013). It considers how ideas around onto-epistemology, intra-activity and agential realism might undo and unknow the researcher’s previous encounters with them. The paper argues feminist new materialism challenges the nature of what counts as data about sexuality at school and thereby the ontology of data about sexuality itself.
Barnehagen som skrivende organisasjon
Authors: Brennås Helene Berntsen
Published: March 2017

Denne artikkelen vil, gjennom posthumane innganger, gi et bilde på hvordan skriving som metode kan synliggjøre og dekonstruere dominerende diskurser, og betydningen overskridelser kan ha for pedagogisk praksis. Jeg har vært opptatt av å gå inn i skriving som overskridende metode, som kunnskaping i, om og med egne praksiser. Gjennom utforskning av teoretiske innganger i møte med datamaterialet er det tre sentrale trekk som utpeker seg når barnehagen som skrivende organisasjon tematiseres, det er betydningen av dekonstruksjon, affektive kaosorienterte forståelser og ontologiske mellomrom for bevegelse av handlingsmønstre i pedagogisk praksis. Er det slik at ved å dekonstruere dominerende diskurser, gjennom affektive kaosorienterte forståelser, skapes det rom for mulige ontologiske mellomrom - som videre kan føre til overskridelser i pedagogisk praksis? Det handler i så måte om hvordan vi gjennom skriftliggjøring av de små og nære hendelser i det levende livet i barnehagen kan dekonstruere dominerende diskurser og bryte etablerte handlingsmønstre, gjennom skrivehistorier som diffraksjonsapparat. Gjennom affektive kaosorienterte forståelser befinner vi oss i et mellomrom mellom det som er og det som kan bli, og i dette mellomrommet forstyrrer og utfordrer vi pedagogiske praksiser som "tas for gitt". På bakgrunn av det kan man gjennom denne studien tenke barnehagen som lærende organisasjon med skriving som overskridende metode som kompetansestrategi.Mine funn kan tye på at skriving som metode gjennom ovennevnte prosesser kan bidra til overskridelser, som deretter skaper mulighetsbilder for å styrke barnehagen som pedagogisk institusjon, samtidig som det åpner for innganger til å nytenke kunnskapsstrukturer - og innganger til barnehagefaglig arbeid.
Early childhood education teachers and leaders becoming the leadership(s)
Authors: Mettiäinen Virpi
Published: March 2017

Leadership research in early childhood education (ECE), and in education generally, has been bur-dened with the notion of effectiveness and how this effectiveness relates to the individual leader. Whereas in this paper, the author attempts thinking and becoming leadership assemblage by draw-ing on Mazzei (2013) use of Deleuze and Guattari’s concept of Body/Voice without Organs. As this conceptualization is closely connected to the notions of becoming and temporality, these aspects will also be discussed in this paper. Thinking together with these theoretical concepts, the author has worked with ECE teacher interviews and ECE leader discussions. This conceptualization can offer new understandings of temporality and becoming in educational leadership.
NLRP6 facilitates the interaction between TAB2/3 and TRIM38 in rheumatoid arthritis fibroblast‐like synoviocytes
Authors: Lin Yang , Luo Zhengqiang
Published: March 2017

In the present study, we investigated the role of nucleotide oligomerization domain‐like receptor family pyrin domain containing 6 (NLRP6) in rheumatoid arthritis (RA) and explored the underlying mechanism. We found that both mRNA and protein levels of NLRP6 are attenuated in synovial tissues and fibroblast‐like synoviocytes (FLS) of RA patients compared to patients with osteoarthritis. We also observed that pro‐inflammatory cytokine production is decreased and nuclear factor‐kappa B activation is inhibited in NLRP6‐overexpressing RA‐FLS. Furthermore, we found that NLRP6 overexpression promotes transforming growth factor‐b‐activated kinase 1‐binding protein 2/3 lysosome‐dependent degradation, and we provide evidence showing that NLRP6 plays the role of providing the docking site to facilitate the interaction between transforming growth factor‐b‐activated kinase 1‐binding protein 2/3 and tripartite motif 38 in RA‐FLS.
Three‐dimensional resistor network modeling of the resistivity and permeability of fractured rocks
Authors: Kirkby Alison , Heinson Graham
Published: March 2017

The resistivity and permeability of 3‐D fracture networks have been modeled as the fractures within these networks are incrementally opened. In these models, the ratio of the rock resistivity to that of the fluid is 104, and the rock permeability is 1 × 10−18 m2. The changes in both resistivity and permeability depend on characteristics of the network itself such as fracture density, as well as the aperture distribution within individual fractures. In dense fracture networks where the density constant α is equal to 30, a percolation threshold can be defined in terms of mean fracture aperture, below which both resistivity and permeability are close to their matrix values. At the percolation threshold, a change in mean aperture of 0.02 mm can change the permeability by 4 orders of magnitude and resistivity by a factor of 4. The percolation threshold does not necessarily occur at the same aperture for different flow directions, so fracture networks near their percolation threshold commonly show anisotropy in both resistivity and permeability. Most sparse networks (α equal to 0.3 or less) do not percolate no matter how open the fractures are. On the other hand, many fracture networks with an intermediate value of α (equal to around 3) will percolate only in one or two directions. This can lead to very strong anisotropy in both resistivity and permeability (up to a factor of 160 and 109, respectively), with anisotropy increasing as the aperture of the fractures increases.
Few‐Layer Graphdiyne Nanosheets Applied for Multiplexed Real‐Time DNA Detection
Authors: Parvin Nargish , Jin Quan , Wei Yanze , Yu Ranbo , Zheng Bing , Huang Ling , Zhang Ying , Wang Lianhui , Zhang Hua , Gao Mingyuan , Zhao Huijun , Hu Wenping , Li Yuliang , Wang Dan
Published: March 2017

Despite recent progress in 2D nanomaterials‐based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few‐layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real‐time detection of DNA with low background and high signal‐to‐noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single‐stranded DNA and double‐stranded DNA. Importantly, for the first time, a few‐layer GD NSs‐based multiplexed DNA sensor is developed.
Effect of diabetes mellitus on postoperative endoscopic sinus surgery outcomes
Authors: Filimonov Andrey , Chung Sei Yeon , Wong Anni , Brady Jacob S. , Baredes Soly , Eloy Jean Anderson
Published: March 2017

Background

Endoscopic sinus surgery (ESS) has become the treatment of choice for a variety of nasal conditions. The purpose of this study was to analyze the effect of diabetes mellitus (DM) on postoperative outcomes in ESS.

Methods

Data on endoscopic sinus surgery performed from 2005 to 2013 were collected from the American College of Surgeons National Surgical Quality Improvement (ACS‐NSQIP) database. Two groups were created, based on the presence of a DM diagnosis, and were analyzed for preoperative variables, comorbidities, and postoperative complications using SPSS statistical software.

Results

There were 644 patients included in the analysis, 85 of whom (13.2%) had a diagnosis of DM. Patients with DM were more likely to have higher rates of preoperative dyspnea and hypertension. After accounting for confounding factors, DM patients undergoing ESS were at higher risk of overall medical complications, pneumonia, unplanned reintubation, ventilator use of >48 hours, and mortality. However, after separating patients into outpatient and inpatient groups, DM was found to be an independent predictor of urinary tract infection in outpatients and of ventilator use >48 hours in inpatients.

Conclusion

DM patients undergoing ESS are at increased risk for postoperative medical complications. However, DM does not appear to increase the postoperative surgical complication rate in this population. Furthermore, DM does not appear to have an impact on ESS mortality, readmission, or reoperation rates.
Light transmission properties in inhomogeneously‐disordered random media
Authors: Xu Yuchen , Zhang Hao , Lin Yujun , Zhu Heyuan
Published: March 2017

Spatially inhomogeneous disorder exists widely in optical systems. We present a numerical study on the light transport properties and analysis of transmission channels in random media with inhomogeneous disorder. For the case of longitudinal inhomogeneity of disorder we find that the statistics of the transmission channels is independent of the inhomogeneity and the system can be equivalent to a counterpart with homogeneous disorder strength, both of which have the same statistical distribution of the transmission channels. However, for the case of transverse inhomogeneity of disorder, such equivalence does not exist. The distribution of the total transmission is broadened and one most transmitted incident channel emerges.
Tightly Bound Double‐Caged [60]Fullerene Derivatives with Enhanced Solubility: Structural Features and Application in Solar Cells
Authors: Brotsman Victor A. , Ioutsi Vitaliy A. , Rybalchenko Alexey V. , Markov Vitaliy Yu. , Belov Nikita M. , Lukonina Natalia S. , Troyanov Sergey I. , Ioffe Ilya N. , Trukhanov Vasiliy A. , Galimova Galina K. , Mannanov Artur A. , Zubov Dmitry N. , Kemnitz Erhard , Sidorov Lev N. , Magdesieva Tatiana V. , Paraschuk Dmitry Yu. , Goryunkov Alexey A.
Published: March 2017

A series of novel highly soluble double‐caged [60]fullerene derivatives were prepared by means of lithium‐salt‐assisted [2+3] cycloaddition. The bispheric molecules feature rigid linking of the fullerene spheres through a four‐membered cycle and a pyrrolizidine bridge with an ester function CO2R (R=n‐decyl, n‐octadecyl, benzyl, and n‐butyl; compounds 1 a–d, respectively), as demonstrated by NMR spectroscopy and X‐ray diffraction. Cyclic voltammetry studies revealed three closely overlapping pairs of reversible peaks owing to consecutive one‐electron reductions of fullerene cages, as well as an irreversible oxidation peak attributed to abstraction of an electron from the nitrogen lone‐electron pair. Owing to charge delocalization over both carbon cages, compounds 1 a–d are characterized by upshifted energies of frontier molecular orbitals, a narrowed bandgap, and reduced electron‐transfer reorganization energy relative to pristine C60. Neat thin films of the n‐decyl compound 1 a demonstrated electron mobility of (1.3±0.4)×10−3 cm2 V−1 s−1, which was comparable to phenyl‐C61‐butyric acid methyl ester (PCBM) and thus potentially advantageous for organic solar cells (OSC). Application of 1 in OSC allowed a twofold increase in the power conversion efficiencies of as‐cast poly(3‐hexylthiophene‐2,5‐diyl) (P3HT)/1 devices relative to the as‐cast P3HT/PCBM ones. This is attributed to the good solubility of 1 and their enhanced charge‐transport properties — both intramolecular, owing to tightly linked fullerene cages, and intermolecular, owing to the large number of close contacts between the neighboring double‐caged molecules. Test P3HT/1 OSCs demonstrated power‐conversion efficiencies up to 2.6 % (1 a). Surprisingly low optimal content of double‐caged fullerene acceptor 1 in the photoactive layer (≈30 wt %) favored better light harvesting and carrier transport owing to the greater content of P3HT and its higher degree of crystallinity.
Comparison of the two modes of the Western Pacific subtropical high between early and late summer
Authors: Dong Xiao , Lin Renping , Fan Fangxing
Published: March 2017

In this work, the first two leading modes of the western Pacific subtropical high (WPSH) between early and late summer are compared. Results show that the first mode of both June and August is featured by an anomalous anticyclonic circulation in the western North Pacific region. The second mode of June (August) is featured by an east–west (south–north) dipole over the North Pacific. Then, the association between the WPSH leading modes and El Niño‐Southern Oscillation (ENSO) is examined. Results show that all PC1s are connected with ENSO developing phase. The connection between June–July–August (JJA) PC2 and ENSO decaying can only be seen in July. In June and August, the connection with ENSO is relatively weak. Finally, the PCs‐related precipitation anomaly is explored. The regressed precipitation anomaly patterns have close connection with the 850‐hPa wind field anomaly. The PC1‐related precipitation shows negative anomaly in the western equatorial Pacific and positive anomaly in the maritime continent. In June a PC1‐related positive rain band is located south to Japan along 30°N, which is absent in August. The PC2‐related positive anomaly in equatorial central Pacific in JJA is mainly attributed to August, while the positive anomaly along the east coast of East Asia is in June and July rather than August. The reasons for the differences between early and late summer are also discussed.
Vergleich der Versagenswahrscheinlichkeit und der Versagenshäufigkeit von Brücken
Authors: Proske Dirk
Published: March 2017

In diesem Artikel werden Versagenshäufigkeiten von Brücken mit den Zielversagenswahrscheinlichkeiten moderner Normen verglichen. Die Bestimmung der Versagenshäufigkeiten basiert im Sinne einer Metaanalyse auf verschiedenen Veröffentlichungen, die sowohl verschiedene Bezugszeiten als auch verschiedene Regionen umfassen. Außerdem werden die Zielversagenswahrscheinlichkeiten für neue und bestehende Bauwerke kurz diskutiert. Der Vergleich der Werte zeigt eine relativ gute Übereinstimmung.
A comparison between the larval eyes of the dimly luminescent Keroplatus nipponicus and the brightly luminescent Arachnocampa luminosa (Diptera; Keroplatidae)
Authors: Meyer‐Rochow V. Benno , Yamahama Yumi
Published: March 2017

Larvae of the weakly blue‐luminescent fungus gnat Keroplatus nipponicus possess on either side of their heads a small black stemmatal eye with a plano‐convex lens approximately 25 μm in diameter. In total, 12–14 retinula cells give rise to a centrally fused rhabdom of up to 8 μm in diameter. The rhabdom's constituent microvilli, approximately 70 nm in width, are roughly orthogonally oriented, a requirement for polarization sensitivity. Screening pigment granules are abundant in the retinula cells and measure at least 1 μm in diameter. In comparison with the stemmatal eye of the brightly luminescent Arachnocampa luminosa, that of K. nipponicus is considerably smaller with a poorer developed lens and a rhabdom that is less voluminous, but possesses wider microvilli. Although the larval eye of K. nipponicus can be expected to be functional, as the larvae react to light with a behavioural response, the eyes are probably mainly involved in the detection of ambient light levels and not, as in A. luminosa, also in responding to the luminescence of nearby conspecifics.
Variation within MBP gene predicts disease course in multiple sclerosis
Authors: Zhou Yuan , Simpson Steve , Charlesworth Jac C. , van der Mei Ingrid , Lucas Robyn M. , Ponsonby Anne‐Louise ,   AUSLONG Investigators Group, Taylor Bruce V.
Published: March 2017

Objective

Prognosis following a first demyelinating event is difficult to predict, with no genetic markers of MS progression currently identified. Myelin basic protein (MBP) is a major component of the myelin sheath of CNS neurons and may play a central role in demyelinating diseases such as MS. However, genetic variation in MBP has not been implicated in MS onset risk in large genome‐wide association studies. We hypothesized that genetic variations in MBP may be a determinant of MS clinical course.

Materials and Methods

We investigated whether variations in the MBP gene altered clinical course (conversion to MS and/or relapse, and annualized change in disability), using a prospectively collected longitudinal cohort study of 127 persons who had had a first demyelinating event, followed up to the 5‐year review.

Results

We found one variant, rs12959006, predicted worse clinical outcomes. The risk genotype (CT + TT) was significantly associated with hazard of relapse (HR = 1.74, 95% CI = 1.19–2.56, p = .005) and of greater annualized disability progression (β = 0.18, 95% CI = 0.06–0.30, p = .004). We also found a significant interaction between the risk genotype and baseline anti‐HHV6 IgG in predicting MS (pinteraction = 0.05) and relapse (pinteraction = 0.02). Functional prediction analysis showed this variant is the target of many transcription factors and the binding sites of miR‐218 and miR‐188‐3p.

Conclusions

Our results provide novel insights into the role of genetic variation within the MBP gene predicting MS clinical course, both directly and by interaction with known environmental MS risk factors.
Reduced arterial elasticity due to surgical skeletonization is ameliorated by abluminal PEG hydrogel
Authors: Robinson Karyn G. , Scott Rebecca A. , Hesek Anne M. , Woodford Edward J. , Amir Wafa , Planchon Thomas A. , Kiick Kristi L. , Akins Robert E.
Published: March 2017

Arteries for bypass grafting are harvested either with neighboring tissue attached or as skeletonized vessels that are free of surrounding tissue. There are significant benefits to skeletonization, but reports suggest that skeletonized vessels may develop structural defects and are at risk for atherosclerosis. We investigated the specific short‐term effects of skeletonization on carotid artery biomechanics and microanatomy in a rabbit model. Six carotid arteries were surgically skeletonized. To support healing, three of these received polyethylene glycol hydrogel injected along their exterior surfaces. M‐mode ultrasonography was used to track circumferential cyclic strain in the skeletonized, hydrogel‐treated, and contralateral vessels. On day 21, the arteries were harvested, and vessel structure was assessed by histology, immunofluorescence microscopy, two‐photon elastin autofluorescence, and second harmonic generation (SHG) microscopy. Intimal‐medial thickness appeared unaffected by skeletonization, but the SHG signals indicated significant changes in collagen turnover in the adventitia. Skeletonized arteries also exhibited significantly decreased radial compliance (circumferential cyclic strain dropped ∼30%) and decreased numbers of elastic laminae (9.1 ± 2.0 to 2.3 ± 1.4). Hydrogel treatment protected against these effects with treated vessels maintaining normal mechanical properties. These results indicate that arterial skeletonization triggers immediate effects on vessel remodeling and reduced vessel compliance resulting in specific tissue alterations within 21 days, but that these effects can be attenuated by the placement of hydrogel on the exterior surface of the skeletonized vessel.
The effect of anatomical placental location on the third stage of labor
Authors: Fidan Ulaş , Ulubay Mustafa , Bodur Serkan , Ferdi Kinci Mehmet , Emre KaraşahiN Kazim , Cemal Yenen Müfit
Published: March 2017

According to the lower uterine segment and trophotropism hypotheses of placental implantation, placentation occurs in uterine segments with a high blood supply. The present study was designed to determine the clinical implications of these hypotheses by assessing the dynamics of the third stage of labor. Two‐hundred and ninety‐two prospectively followed pregnant women were assessed at the time of delivery. The uterine locations of the placentas were determined according to the position of the main placental volume and mass under a sagittal view obtained using a centrally located ultrasonography probe. Depending on the location of the placental mass, the patients were assigned to three groups: anterior, posterior, and fundal. The placenta was located in the anterior, posterior, and fundal wall in 52.7% (154/292), 37.7% (110/292), and 9.6% (28/292) of cases, respectively. The duration of the third stage of labor was 6.26 ± 3.89, 6.47 ± 3.68, and 7.42 ± 3.67 min in the anterior, posterior, and fundal placental groups, respectively (P = 0.06). The placenta was separated peripherally in 25% (n = 73) of the patients in each group and centrally in 75% (n = 219). The delta hematocrit value (hematocrit change) was 2.99 ± 4.39, 3.15 ± 6.52, and 2.76 ± 3.04 in the anterior, posterior, and fundal groups, respectively (P = 0.99). This study showed that the location of the placenta did not affect the dynamics of the third stage of labor. Clin. Anat. 30:508–511, 2017. © 2017 Wiley Periodicals, Inc.
Relational conversation: Linking head and heart as a means to transformation
Authors: Macaskie Jane
Published: March 2017

Aims

A study of therapists’ experiences of transformation generated conversational moments typical of the experiences being studied. This paper outlines dialogical moves within research conversations and suggests that these contribute to linking thinking and feeling, head and heart, within an intersubjective matrix, which may be therapeutic.

Method

Video recordings of research conversations were reviewed by researcher and co‐researchers using an adaptation of Interpersonal Process Recall, and key moments were analysed dialogically.

Findings

Following Stern's (The Present Moment in Psychotherapy and Everyday Life. 2004. New York: W.W. Norton) concept of moments of meeting, additional moments of not‐meeting, reflective moments of meeting and shared interest focus were identified, all functioning as building blocks of intersubjective connection and integration.

Discussion

Reflective moments of meeting in particular appear to be central to integrating thinking and feeling. Transformational opportunities appear to arise from such integration, while their absence seems to arise from a failure to integrate.

Implications for practice

A therapeutic model is presented focusing on the role of reflection within the intersubjective experiencing of therapist and client. Implications for reflective practice are suggested.

Conclusions

Attention to dialogical moves demonstrates the potential of research conversations to facilitate transformation for co‐researchers via the integration of thinking and feeling in reflection. Further research is suggested to track similar processes in therapy.