bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence Factor Analysis of Consumer Decision in Using Special Tariff Policy on Regional Rail in Indonesia (Case Study : Sawunggalih Regional Train)
Authors: Baldat Agil Gian , Septiani Isse Liana , Andriansyah Yuda , Sugiyanto Martinus Agus , Hariani Mira Lestira
Published: December 2024

Indonesian railway transportation service companies are constantly striving to improve service and facility optimization while increasing train passenger numbers. The purpose of this study is to examine the impact of special fare tickets on train user decisions in order to boost passenger traffic and strengthen railways' role in the regional economy. This study examines price, time (length), and certainty opportunities as influences on the decision to acquire special fare tickets for public transportation trains. The study took a quantitative approach, with the questionnaire asking about Ability to Pay (ATP) and Willingness to Pay (WTP). Furthermore, the data was examined using multiple linear regressions to identify the impact of variables on consumer behavior. Overall, 54% of respondents can buy rail tickets at official pricing, including regular and special fares. 44% of respondents always purchase special price train tickets for long journeys and always take trains. Therefore, the resulting regression model is as follows: Y=3.115 - 0.49X1 + 0.042X2. The price variable shows a negative influence (-0.49), indicating that the greater the ticket price, the less likely someone will purchase a special fare train ticket. In contrast, the time variable has a positive effect, with a value of + 0.043, indicating that the longer the time given, the more likely someone will opt to buy.
ÖRGÜTSEL YAŞAMDA DUYGU YOKLUĞUNUN DUYGU BIKKINLIĞINA DÖNÜŞÜMÜ: DUYGUSAL EMEK YAYILIMI
Authors: Eroğlu Şeyma Gün , Bayrak Kök Sabahat
Published: December 2024

Duygu konusunun insan yaşamındaki önemine rağmen örgütsel yaşamda uzun süre görmezden gelindiği görülmektedir. Klasik yaklaşım döneminde duygu konusu, irrasyonelliği bertaraf etmek adına uzun süre bir kenara bırakılmış, örgütlerde akılcılığı yapılandırmak anlayışıyla hemen hemen hiç üzerinde durulmamıştır. 1980’den sonra yönetim süreçlerinde yaşanılan çok boyutlu değişimler, rekabette üstünlüğün değişen unsuru olarak emek gücünü öncelemeğe başlamış ve böylece duygulara yaklaşım yeni bir perspektif kazanmıştır. Bu yıllar itibariyle, örgütlerin iş yapma yeteneklerini harekete geçiren, durduran veya yavaşlatan temel güdüleyicinin insan emeği ve özellikle onun duygusal boyutu olduğuna dikkat çekilmiştir. Bu, herhangi bir kişinin, kendinden beklenen işi etkili bir şekilde yerine getirebilmesi için mevcut yeteneklerini işe tam kapasite ile katabilmesi demektir. Bu perspektif günümüzde insanın duygusal yönünün kullanımına yoğun bir talep yaratmıştır. Hatta duygusal bir aşınma yaratacak kadar ciddi bir yayılım etkisi yaşadığına dikkat çekilerek konu duygusal tükenmişlik ile ilişkilendirilmektedir. Özellikle emekle ilişkili bu yeni pozisyon, Hochschild’in tarafından ‘duygusal emek’ şeklinde tanımlanarak kavramsallaştırılmıştır. Makale, örgütsel yaşamda duygu yoksunluğunun duygu aşınması yaratacak bir bıkkınlık seviyesine nasıl ulaştığını, hizmetler sektörüyle ilişkilendirerek açıklamayı amaçlamaktadır.
Conversatorios sobre Psicología del Trabajo y Organizacional en Guatemala (Sistematizaciones)
Authors: Linares Sindy S. , Guillén Barillas Miguel Alfredo
Published: December 2024

El primer conversatorio de Psicología del Trabajo y Organizacional de la Escuela de Ciencias Psicológicas de la Universidad de San Carlos de Guatemala, permitió un enriquecedor intercambio de conocimientos y experiencias entre participantes de diversas disciplinas y niveles de experiencia, abordando temas críticos como la precarización del trabajo y el estrés laboral, la gestión del riesgo psicológico y psicosocial, y las leyes y políticas públicas relacionadas. Se subrayó la importancia de un enfoque estructural e integral que contemple tanto cambios legislativos como acciones prácticas dentro de las organizaciones para mantener un entorno de trabajo saludable y productivo. Los días 17, 19, 24 y 26 de abril contaron con la participación de destacados profesionales como el Dr. Jorge Sandoval, la Lic. Malen Muñoz, la Lic. Silvana María Losi Garzaro, el Dr. Luis Manuel Fernández Hernández, la Lic. Diana Cameros, el Dr. Julio Neffa, el Dr. Erico Rentería y el Lic. Carlos Recinos, con la moderación de expertos como el Mtro. Miguel Guillen, la Doctoranda Mónica Pinzón González, la Lic. Sindy Linares y el Doctorando Mariano González. El evento resaltó la necesidad urgente de priorizar los riesgos psicosociales en el trabajo, que fueron identificados como una prioridad no atendida adecuadamente en Guatemala y otros países de América Latina, para fomentar cambios legislativos y acciones concretas dentro de las organizaciones.
Exploración de Niveles de Competencias Clínicas de los Estudiantes de la Licenciatura en Psicología en Intervención en Casos Suicidas
Authors: Auyón Marroquín Patricia Carolina , Rodas Jorge Ernesto
Published: December 2024

El suicidio es uno de los motivos de consulta más frecuentes dentro de la psicoterapia. Frente al aumento de casos de intento, el psicólogo clínico y psicoterapeuta debe poseer las competencias necesarias para brindar un abordaje adecuado y ético. El presente artículo aborda la percepción de los futuros profesionales de la psicología entorno al grado de dificultad de sus competencias básicas clínicas frente a la intervención de casos suicidas. La muestra se compuso de 30 participantes entre estudiantes del cuarto año y quinto año de la práctica supervisada como estudiantes con cierre de pensum en la licenciatura de Psicología de la Escuela de Ciencias Psicológicas de la Universidad San Carlos de Guatemala. El diseño de investigación fue bajo un enfoque mixto con alcance exploratorio en donde se utilizaron métodos cuantitativos para medir el grado de dificultad de fenológico en donde su utilizo una entrevista semiestructurada para explorar la experiencia subjetiva de los participantes. Los resultados demostraron que los participantes perciben con gran facilidad la mayor parte de sus competencias, aunque señalaron dificultad en relación a competencias ligadas a su rol como terapeutas, manejo de la entrevista y manejo de variables contextuales.
Investigating UX work in Software Startups: A Survey about Attitudes, Methods, and Key Challenges
Authors: Guerino Guilherme , Martinelli Suéllen , Choma Joelma , Leal Gislaine Camila , Balancieri Renato , Zaina Luciana
Published: December 2024

User eXperience (UX) work within the software industry entails implementing user-centered practices and techniques to acquire and apply insights about users. Given their challenging context characterized by small teams and limited resources, this application can provide software startups with a competitive edge. Despite a growing interest in this field, the perspectives of startup professionals regarding UX work and the challenges they face remain largely unexplored. This paper seeks to explore the perceptions of startup professionals regarding the usefulness of methods and techniques used in UX work, as well as the moments during user interactions with the product or service when they are applied, alongside the challenges inherent in the startup environment. To achieve this, we conducted a survey involving 90 professionals from software startups in Brazil, employing descriptive and inferential statistical methods for data analysis. Our findings reveal that software startup professionals prioritize understanding user needs, capturing feedback, and conducting user tests in their UX work. Interviews are the most commonly utilized method, although usability testing, competitive analysis, and high-fidelity prototyping are also valued across various stages of startup maturity. Furthermore, UX data is primarily collected during user interactions with the product. Additionally, we identified that specific challenges may have a reciprocal relationship with UX attitudes. These findings underscore the perceived value of UX work among software startup professionals, although perspectives vary depending on the startup's stage.
Uso da Inteligência Artificial por surdos para correção de textos escritos
Authors: Leite Ana Carla Kruger , Oliveira Márcia Gonçalves de , Xavier Gabriel S. Nascimento
Published: December 2024

A Inteligência Artificial (IA) desempenha um papel revolucionário para o desenvolvimento de diversas áreas, sobretudo pelo emprego de técnicas de Processamento de Linguagem Natural (PLN) comuns em softwares usados para produção, correção e tradução de textos. Este artigo se volta para as possibilidades de utilização da IA na produção escrita de surdos, cujo desafio de lidar com a escrita oriunda de uma língua oral constitui uma barreira de acesso à informação. Nesse sentido, partimos da experiência de uma pesquisadora surda na utilização de ferramentas de correção e tradução automática como estratégia de produção de textos científicos. As análises indicam um potencial de escrita com maior autonomia para surdos, sobretudo no contexto da pós-graduação, que demanda um exercício de escrita constante.
Graphite Plate for Pervaporation Wound Therapy
Authors: Omujal Francis , Mukisa Joseph
Published: December 2024

Graphitized carbon black is one of the carbon adsorbent biomaterials claimed to treat venomous wounds, but its efficacy has been debated by scientists. We have endeavored to explain the principle of the black stone as a graphite plate in wound therapy. The graphite plate is prepared using cattle and fish bones by pyrolysis. It has the ability to create vapor-pressure difference and promote toxin dehydration in the wound. In the process, bacterial membrane disruption and a reduction in reactive oxygen species production around the wound occurs. The permeant vapor decrease in the wound then reduces the swelling and bacterial infection on the wound surface, thus stimulating the growth of new tissue around the wound and vaporization of toxin. This promotes the secretion of growth factors that facilitate angiogenesis and extracellular matrix deposition in the wound, resulting in the release of cytokines for immune response regulation. The graphite plate can also affect the microenvironment around the wound including pH, temperature and reactive oxygen levels. Therefore, the graphite plate pervaporation is a promising and effective technique for the removal of trace amounts of organic material and infections introduced into the wound.
Unveiling the Role of Arbuscular Mycorrhiza in Seed Germination
Authors: Dutta Suman , Paul Debashis , Garai Sourav , Roy Anirban , Kumar Sudhir
Published: December 2024

Seed germination is a pivotal stage in the life cycle of plants, marking the transition from dormancy to active growth. Arbuscular Mycorrhizal (AM) fungi form symbiotic associations with the roots of most terrestrial plants, profoundly influencing various aspects of plant growth and development. This chapter provides a comprehensive exploration of the intricate relationship between AM fungi and seed germination, spanning genetic, molecular, ecological, and practical dimensions. Moreover, insights into hormonal regulation, mycorrhizal networks, soil conditions, and ecological implications mediated by AM fungi in modulating seed germination processes are also discussed. The chapter also addresses the role of AM symbiosis in conferring abiotic stress tolerance to seeds, particularly under drought, salinity, and temperature stress. Practical applications and management strategies involving the utilization of AM fungi in agriculture and restoration ecology are outlined, emphasizing their potential to improve seed germination rates and facilitate ecosystem restoration efforts. Challenges and future directions are discussed, underscoring the need for continued research to fully harness the benefits of AM symbiosis for sustainable plant growth and ecosystem management. In conclusion, this chapter offers a comprehensive synthesis of the role of AM fungi in seed germination, emphasizing its multidimensional impacts and potential applications across various fields.
Perspective Chapter: Global International Relations
Authors: Oren Eitan
Published: December 2024

This chapter examines the emerging scholarship on Global International Relations (Global IR), placing it in a broader disciplinary context. I review Global IR’s key claim (Mainstream International Relations Theory is inadequate), introduce its main tenets, benefits, and criticisms levelled at it, discuss one study of Global IR, and evaluate the extent to which it challenges mainstream IR theory. Having shown the contribution Global IR can make to our discipline, I point out five risks in doing Global IR and offer two ways to mitigate the substantial risk of essentialism. The conclusion makes the case for Global IR to promote greater epistemological innovation.
Competencies Replaceable by Artificial Intelligence in the Tuning Project for Latin America
Authors: Antonieta Romero-Sandoval Adriana
Published: December 2024

The Tuning Project for Latin America aims to harmonize competencies and learning outcomes in higher education, focusing on key generic competencies. This study explores how artificial intelligence can complement or replace these competencies using a systematic PRISMA methodological approach to identify qualitative literature on the application of AI in everyday activities. A total of 256 publications were analyzed, highlighting how AI can replace or complement the generic competencies of the Tuning Project in higher education, emphasizing its impact on education and professional adaptability and competitiveness. Recent literature underscores the transformation that artificial intelligence (AI) is generating in various fields and the labor market. An increase in publications shows a growing interest in its capacity to enhance and substitute generic competencies, driving the need to balance technological dependency with fundamental human skills. Curricular adaptation and the integration of innovative methodologies are essential to improve employability and education in a changing labor environment, further fostering social responsibility and professional ethics. Artificial intelligence (AI) is transforming education and the professional realm by enhancing and replacing generic competencies, despite its limitations in areas requiring creativity and empathy.
Systems Thinking on Artificial Intelligence Integration into Higher Education: Causal Loops
Authors: Zhing Liew Yee , Huey Ping Tan Andrew , Hwa Yap Eng , Shen Lim Chee , P.P. Abdul Majeed Anwar , Zhu Yuyi , Chen Wei , Chen Shu-Hsiang , Ying Tuan Lo Joe
Published: December 2024

This chapter employs a system dynamics lens to examine the intricate interplay between artificial intelligence (AI) integration and the landscape of higher education. Employing causal loop diagrams, it delves into the evolving dynamics of various key indicators in higher education affected by AI implementation. Beginning with an overview of disruptive technologies’ current roles in academia, including AI, it proceeds to illustrate the interrelationships in the form of feedback loops between technological advancements, pedagogical methodologies, institutional structures, and societal factors. Subsequently, it explores the systemic shifts in student learning experiences, faculty roles, and administrative practices catalysed by AI infusion. By illuminating the complex web of interactions, this chapter aims to provide insights crucial for fostering a harmonious and effective integration of AI within higher education systems.
Functional Transition Metal Oxides: Novel Photocatalytic Applications and Engineering Perspectives
Authors: Yelgel Celal , C. Yelgel Övgü
Published: December 2024

Solar-powered catalytic reactions are attractive for addressing energy and environmental issues. Photocatalysts are chemically stable semiconductors that initiate chemical reactions in adsorbed molecules when photoexcited charge carriers diffuse to the surface. The interface properties of photocatalysts play a crucial role in improving charge separation and charge transfer processes in photocatalytic reactions. Transition metal oxides (TMOs) are widely used as photocatalysts due to their excellent stability, affordability, abundance on Earth, and remarkable catalytic activity. Recent advancements in nanomaterial growth have significantly accelerated research in this field. This allows for fine-tuning catalyst performance by controlling the morphology of powder catalysts. Recent developments in surface characterisation of oxides have provided a deeper understanding of the atomic structure of surfaces and their interaction with the environment. The discovery of novel surface phases exhibiting unique electrical characteristics has opened up new routes for enhancing the performance of photocatalytic materials.
Conjunction of Grammatical Cohesion in BBC News About Taylor Swift is Time’s 2023 Person of The Year
Authors: Alam Beny
Published: December 2024

This study examines how conjunctions are used in BBC news articles, with a particular focus on the article titled “Taylor Swift is TIME’s 2023 Person of the Year”. By identifying different types of conjunctions, this study categorizes them into external and internal types and analyses their role in ensuring sentence coherence. Conducted over six months at STBA JIA, this study adopts a descriptive qualitative method and is based on Halliday and Hasan (1976) theory of grammatical cohesion. The findings indicate that simple additive conjunctions are the most frequent, accounting for 33.33% of all instances. Temporal conjunctions follow, with 29.16% for simple types and 8.4% for complex types. Among the classifications, external conjunctions dominate at 87.5%, reflecting the emphasis on real-world connections and events presented in the news.
George Orwell’e Ait 1984 Romanının Yeniden Çevirileri: Pierre Bourdieu’nün Sermaye Kavramı Üzerinden Bir İnceleme
Authors: Kayahan Selvin
Published: December 2024

Bu çalışma, George Orwell'in 1984 adlı romanının Türkçeye yapılan yeniden çevirilerini Fransız sosyolog Pierre Bourdieu'nün sermaye kavramı çerçevesinde incelemektedir. Orwell'in 1949 yılında yayınlanan, en az 65 farklı dile çevirisi yapılarak milyonlarca kişi tarafından okunmuş olan bu başyapıtı, 1958'de ilk kez Türkçeye çevrilmiş ve 2020 yılında telif süresinin sona ermesinin ardından birçok yayınevi tarafından yeniden çevrilmiştir. Çalışmada, 1984'ün yeniden çevirilerinin, yayınevlerine ekonomik, kültürel, sosyal ve simgesel sermaye kazandırmadaki rolü değerlendirilmiştir. Pierre Bourdieu'nün alan, habitus ve sermaye kavramları bu incelemenin teorik temelini oluşturmaktadır. Bourdieu’nün sosyolojik yaklaşımı, bir eserin çevirilerinin ekonomik, kültürel ve simgesel sermaye bağlamında nasıl etkiler yarattığını analiz etmek için bir çerçeve sunar. Ekonomik sermaye, yayınevlerinin kâr elde etme amaçlarını; kültürel sermaye, çevirmenlerin ve yazarların bilgi ve uzmanlıklarını; sosyal sermaye, yayınevlerinin oluşturduğu ağları; simgesel sermaye ise prestij ve tanınırlık gibi soyut değerleri ifade etmektedir. Çeviri sürecinin, yayınevleri, çevirmenler ve okurlar arasındaki güç dinamiklerini yansıttığı tartışılmıştır. Araştırma, yeniden çevirilerin sadece dilsel ya da kültürel bir gereklilikten değil, ticari ve simgesel nedenlerle de yapıldığını varsaymaktadır. Yayınevleri, 1984 gibi klasik eserlerin yeniden çevirilerini, pazardaki talepleri karşılamak, prestij kazanmak ve kültürel sermayelerini artırmak amacıyla tercih etmektedir. Orwell'in 1984 eserinin yeniden çevirileri, sadece edebi bir faaliyet değil, aynı zamanda toplumsal, kültürel ve ekonomik güç ilişkilerini yansıtan bir olgudur. Bu bağlamda çalışma, çeviri sosyolojisi alanına katkı sağlamaktadır.
حاکمیت قانون و پیامدهای آن در حقوق افغانستان
Authors:   دانش‌جوی دکتری حقوق کیفری و جرم‌شناسی، دانش‌گاه/ پوهنتون بین‌المللی اهل‌بیت (ع)، تهران، ایران و هیئت‌علمیِ دیپارتمنت‌ حقوق، پوهنځی/ دانش‌کدۀ حقوق و علوم سیاسی، پوهنتون/ دانش‌گاه جامی، هرات، افغانستان, شریفی زیرکسار حسین
Published: December 2024

حاکمیت قانون به‌عنوان زیربنای دولت قانون‌مدار، از اصول بنیادین حقوقی در جوامع مترقی محسوب می‌شود. این اصل، که برای حفظ قدرت و اقتدار کشور و تنظیم حقوق و آزادی‌های شهروندان به‌کار می‌رود، پیامدی اساسی چون تأمین عدالت اجتماعی و حقوق اساسی شهروندان را در پی دارد. با توجه به این‌که عدالت اجتماعی یکی از مؤلفه‌های ضروری یک جامعۀ پیش‌رفته است، بررسی مبانی تأمین آن از اهمیت ویژه‌‌یی برخوردار است. هدف این پژوهش، تبیین حاکمیت قانون و پیامدهای آن با تأکید بر حقوق افغانستان بوده و تلاش کرده است به این پرسش پاسخ دهد که: حاکمیت قانون چه پیامدهایی دارد؟ این پژوهش به روش توصیفی - ‌تحلیلی و با بهره‌گیری از منابع کتاب‌خانه‌یی انجام شده است. یافته‌های پژوهش نشان می‌دهند که مهم‌ترین پیامد حاکمیت قانون، تأمین عدالت اجتماعی و حقوق اساسی شهروندان است. این امر از طریق تدوین قوانین کیفی و اجرای عادلانۀ آن‌ها محقق می‌شود. بر این اساس، کنش‌گران حوزۀ کیفری باید در مراحل تعیین مجازات و اجرای آن مستقل و بی‌طرف عمل کنند و مجازات‌ها را با درنظرگرفتن شرایط متهم و مقتضیات جامعه تعیین و اجرا نمایند. علاوه بر این، اجرای قانون باید به‌گونه‌یی باشد که شهروندان ضمن تطبیق رفتارهای خود با قانون، احساس امنیت کنند؛ امری که به برقراری نظم، امنیت اجتماعی و صلح در جامعه منجر می‌شود.
Unravelling the Complex Interplay of Genetic Environmental Factors in Hirschsprungâ€™s Diseases
Authors:   Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Vadodara, Gujarat, India., Shah Hetvi , Shah Riddhi , Rathod Dr. Mrudangsinh ,   Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Vadodara, Gujarat, India., Parekh Dr. Kushal , Dudhat Dr. Kiran ,   School of Pharmacy, RK University, Rajkot, Gujarat, India.
Published: December 2024

The interconnection of single-gene mutations and environmental exposures to produce complex disorders may represent one of the most significant obstacles in disease gene discovery. Polygenic background, numerous and infrequent variations, and gene-gene interplay affect are the main reasons why complex diseases occur. In personalized medicine, the solutions are based on the prediction of the identification of an individual's health status by a high-volume genetic analysis as well as bio-environmental factors. Whether it is a consideration of a normal or abnormal gene order, each should be taken into account in order to understand the basic complex requirements of health. Though it is quite challenging, the initial stage that involves the identification of common and unusual sources of genetic variation in individuals with higher disease likelihood is the foundational step. The role of multifactorial and unifactorial genetic variations in the etiology of HSCR was further examined in the literature as well. SNPs, on the other hand, are general genetic variants that at most times are detected in population with frequencies at 5% and above. Hypothetical risk is elevated by spontaneous varying in other genes and rare genetic variants on RET gene, which were shown to induce HSCR. Feature genetic factors influencing HSCR formation and development can be clarified by studying the common variations between HSCR and other disorders shown by GWAS research. Research from the HSCR could increase the likelihood of specific drugs for precision medicine, which will be customized to varieties of individual patientâ€™s genome. Investigations of translational research, function, long-term studies, and the possibilities of gene-environment interactions, whole-genome sequencing, and a population oversample incorporate the broad aspects of future research topics.
Burden, Issues and Prospects of Prostate Cancer in Nigeria: A Review of Studies
Authors:   Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, Madonna University Elele, River State, Eustace Egere , Brian O Ogbonna ,   Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Nigeria
Published: December 2024

Background: Prostate cancer has constituted a big public health challenge, evidenced and characterised by increasingly high incidence and prevalence rates.

Objective: This study narratively reviewed the incidence, prevalence, burden, issues and prospects of prostrate cancer in Nigeria to generate evidence for policy and planning.

Methods: The research was a narrative review of all studies conducted on the incidence, prevalence, burden, issues, and prospect of prostrate cancer in Nigeria from 1970 to 2023.

Overall, total of 139 articles were obtained, 79 from Pubmed, 35 from ResearchGate and 10 from Google Scholar. After a thorough evaluation, 55 duplicate articles were screened out, and 50 articles were also excluded for not covering the scope of incidence, prevalence, burden, issues, and prospect of prostate cancer in Nigeria. A total of 33 articles were used for the study. Data were summarized and presented in evidence-based tables.

Results: The studies obtained were predominantly retrospective and cross-sectional studies. Most of the studies were carried out between 2010 to 2023. Prostate cancer screening uptake was hampered by socioeconomic constraints and poor risk perception. Early detection might be enhanced by population-based PSA screening, however economics must be considered.

Conclusion: The increase in the rates of incidence and prevalence of prostate cancer from 1970 to 2023 makes it necessary to call for strategic health policymakers for immediate interventions to stop the trends. These trends are largely affected by lifestyle factors, age, and poor information in the awareness of the disease.
Exploring the Clinical Impact of Magnetite Nanoparticles in a Multifaceted Approach to Treating Multiple Sclerosis
Authors:   Kharkiv National Medical University, Ukraine., Belousov A.N. , Belousova E.Yu. ,   Laboratory of Applied Nanotechnology of Belousov., Mysyk A.V. ,   Krasnokutsk Central District Hospital, Ukraine.
Published: December 2024

Multiple sclerosis (MS) is a serious neurological disorder due to its widespread prevalence, chronic nature, frequent progression to disability, and tendency to affect young people. The pathogenesis of MS is based on the immunopathogenesis hypothesis. Biocompatible magnetite nanoparticles, which exhibit selective sorption activity towards cell membrane surface proteins, circulating immune complexes, lymphocytotoxic antibodies, and the complement system, as well as enhance phagocytic activity and the completion index of leukocyte phagocytosis, can be effectively used for immunocorrection. The main goal of the study is to slow the progression of MS, improve the neurological status and overall condition of the patient, and reduce the dynamics of the spread of demyelinating lesions in the brain. Materials and methods: A patient diagnosed with multiple sclerosis, secondary progressive type, cerebrospinal form, at the clinical aggravation stage was included in the study. Neurological status and disability were assessed using the EDSS scale, and brain MRI with contrast enhancement was performed. The nanodevice Micromage-B was administered orally as an immunosorbent and immunomodulator. The regimen and dosage of Micromage-B were personalized. Assessments of general condition and neurological status were conducted every 7 days for 6 months, with contrast-enhanced brain MRI performed in the 5th month. Results: The use of Micromage-B in MS treatment led to an objective improvement in neurological status, with reduced stiffness and fatigue in the lower extremities. Gait and coordination improved, hand tremors decreased, depression and concentration disorders subsided, appetite was restored, and speech improved. Throughout the treatment period, positive dynamics in the normalization of neurological status were observed. After 6 months, the total score on the EDSS scale decreased from 210 to 45. The most significant improvements were observed in the evaluation of the pyramidal system and coordination, with the EDSS Disability Scale score decreasing from 6.0 to 5.0. For the first time, contrast-enhanced brain MRI showed a reduction in the number of new demyelination foci by the 4th month of Micromage-B administration. The positive changes in neurological status correlated with the MRI results. The recovery of central nervous system activity in MS is likely not only due to the immunosuppressive properties of magnetite nanoparticles but also due to the activation of remyelination mechanisms and oligodendrocyte differentiation through enzymatic methylation. Conclusion: The use of biocompatible nanodevices in the complex treatment of MS is promising. Further improvement and study of the regimen and method of using biocompatible magnetite nanoparticles to enhance MS treatment effectiveness are required.
Pengaruh Manajemen Kurikulum Berbasis Kompetensi terhadap Kompetensi Soft Skills dan Hard Skills Lulusan SMA
Authors: Pertiwi Ila Indah , Eljohn Grace , Fitriah Nur Indriana , Warman Warman
Published: December 2024

The Competency-Based Curriculum (KBK) approach is one of the solutions that is expected to be able to answer the needs of the times. However, reality shows that many high school graduates still face challenges in optimally integrating hard skills and soft skills. This study aims to analyze the influence of Competency-Based Curriculum management on the development of soft skills and hard skills competencies of high school graduates. This study uses a quantitative approach with a survey method to analyze the influence of Competency-Based Curriculum management on the development of soft skills and hard skills of high school graduates. This study shows that the management of the Competency-Based Curriculum (KBK) at the high school level has a significant positive influence on the development of students' soft and hard skills. From the aspect of curriculum management, planning obtained the highest score (85 out of a scale of 100), followed by implementation (80) and evaluation (78), which shows that the school has made optimal efforts in designing and implementing KBK, although the evaluation stage still needs improvement. In the development of soft skills, communication and cooperation skills received the highest scores of 85 and 84, respectively, while leadership and time management obtained scores of 75 and 72. On the other hand, students' mastery of hard skills is also in the good category with the highest score on technology-based skills (86) and the lowest score on analytical skills (74). The results of the linear regression test confirmed that there was a significant positive relationship between KBK management and the mastery of soft skills (regression coefficient 0.65; p < 0.01) and hard skills (regression coefficient 0.59; p < 0.01).
Hubungan antara Kecemasan dan Motivasi Belajar pada Siswa Sekolah Menengah Atas (SMA)
Authors: Grace Viona , Kartasasmita Sandy
Published: December 2024

Education has an important role in developing students‘ abilities, but significant changes in the education system, such as curriculum changes, and academic requirements often put pressure on students so that it can trigger anxiety and have an impact on students’ learning motivation. This study aims to determine the relationship between anxiety and learning motivation in high school students. The method used was a quantitative method involving 206 high school student participants based on purposive sampling. This study used the spearmen corellation method and the results showed that there was no relationship between anxiety and learning motivation of high school students. The correlation test results obtained an r value of -0.017 and p 0.814> 0.05. The results of the difference test using mann whitney and obtained there are differences in anxiety based on gender and differences in learning motivation based on grade level. The results of this study are expected to be useful for future researchers in conducting research with similar variables and useful for teachers to develop learning methods that can reduce student anxiety and can increase student learning motivation.
Rare Case of Human Herpes Virus-6 Meningitis in Immunocompetent Adult Patient Presented as Decrease Level of Consciousness
Authors: A. Albaiti Omar , Wali Ghassan , Ali Bayan
Published: December 2024

Background: Human herpesvirus 6 (HHV-6) is typically known for causing roseola in children, but its role in
encephalitis among immunocompetent adults is less documented.
Case Presentation: We report a case of a 35-year-old Indonesian male with no significant medical history, who was
admitted in August 2024 with high fever and altered consciousness. Symptoms began 10 days prior, escalating from
fever to severe headache and neck stiffness. Initial treatment with paracetamol and levofloxacin was ineffective.
Neurological examination revealed reduced consciousness (GCS 9/15) and behavioral abnormalities. Investigations
included a CT scan, blood tests, and CSF analysis.
Investigations: Initial CSF analysis showed elevated protein and lymphocyte predominance. The CSF FilmArray
Meningitis Panel confirmed HHV-6 infection. EEG indicated cerebral dysfunction, and MRI revealed non-specific white
matter changes.
Treatment and Follow-Up: The patient received empirical treatment with vancomycin, ceftriaxone, and acyclovir, later
switched to ganciclovir, leading to significant recovery. Follow-up indicated resolution of fever and neurological
symptoms.
Discussion: This case underscores HHV-6 as a potential cause of severe encephalitis in immunocompetent adults. The
effectiveness of the FilmArray Meningitis Panel in diagnosing HHV-6 emphasizes the need for awareness of this virus in
encephalitis cases. Further research is needed to refine treatment and diagnostic protocols for HHV-6 infections.
Conclusion: HHV-6 should be considered in the differential diagnosis of encephalitis in adults, especially when common
pathogens are excluded. Improved understanding and treatment strategies are essential for better patient outcomes.
Oral Tranexamic Acid Does Not Improve Arthroscopic Visibility During Rotator Cuff Repair
Authors: López-Villers Alejandro , Rojas Avilés José Luis , Valencia-Ramón Edwin , González-Rizo Israel , Franco del Río Guillermo R. , Guevara-Álvarez Alberto
Published: December 2024

Objective: To evaluate the quality of arthroscopic visibility during rotator cuff repair using oral Tranexamic Acid (TXA).
Secondary objectives included evaluating whether oral TXA administration has any impact on cerebral oxygenation,
mean arterial pressure (MAP), irrigation pump pressures, surgical and anesthetic times.
Methods: A prospective, comparative, randomized, double-blinded study was conducted on patients treated by
arthroscopic rotator cuff repair. The sample was divided into 2 groups: group A (n=24) received oral TXA 30 minutes
before the procedure and group B (n=20) was the control group without oral TXA. Variables were compared at 4
different surgical moments (tenodesis, rotator cuff repair, subacromial decompression, acromioclavicular
decompression). Visibility was categorized into 2 grades (grade I “poor visibility” or grade II “good visibility”), values for
cerebral oxygenation, MAP, irrigation pump pressures, surgical and anesthetic times were compared.
Results: The study included 44 patients, with a mean age of 57 years. Visibility was significantly better during tenodesis
in group A (p < 0.001), but there were no differences at other surgical moments. Cerebral oxygenation was higher in
group A (p < 0.05) at all surgical moments. There were no statistically significant differences in MAP control, irrigation
pump pressures, or surgical and anesthetic times.
The Influence of Islamic Character Education in Extracurricular Activities on Strengthening Students' Mental and Moral Aspects
Authors: Khodijah Siti , Asiah Siti , Kamaludin Dede , Komalasari Winda , Fitri Anisa , Diena Qoyyimah Fika , Lastika Adiansyah Nunung
Published: December 2024

Globalization has had a significant impact, both positive and negative, on Indonesian society, especially in the moral and mental aspects of the younger generation. Phenomena such as declining moral values, deviant behavior, and mental problems are challenges that need to be addressed through effective character education. This study aims to analyze the role of Islamic character education through extracurricular activities in strengthening the mental and moral aspects of students at MI Hidayatul Mukhlisin. The method used in this research is a qualitative approach with a case study method. Data were collected through in-depth interviews, observations, and document analysis related to the implementation of extracurricular activities based on Islamic character education at the school. The results showed that extracurricular activities such as scouts and Islamic values-based activities play a significant role in shaping students' characters. Islamic character education through these activities succeeds in: (1) improve students' morality and ethics, (2) strengthen spiritual and social aspects, (3) form Islamic personalities, and (4) build mental resilience in facing various life challenges. The implication of this research confirms the importance of integrating Islamic values in extracurricular activities as a strategy to form a young generation that is noble, has strong morals, and is able to adapt to the demands of globalization. Recommendations are given to schools to improve the planning and implementation of character-based activities and to extend this research to other school contexts for more generalizable results.
Ahlak Temelli Ekonomi: İslam Ahlak Ekonomisinin Kuramsal Temelleri ve Bileşenleri
Authors: Karadoğan Sercan
Published: December 2024

Bu makale, İslam ahlakının ekonomik sistem üzerindeki kurucu rolünü ele almaktadır. Çalışma, İslam’da ahlak ve ekonominin ilişkisini tarihsel ve çağdaş bağlamlarda inceleyerek İslam ekonomisinin temellerini ve bileşenlerini değerlendirmektedir. İslam’da ve özellikle Kur’an’da ahlak ve ekonominin hangi kavramlar bağlamında ele alındığı incelendikten sonra, İslam ekonomisi literatüründe yer alan farklı sosyo-ekonomik modeller ve örnekler üzerinden bir tartışma yürütülmektedir. Ekonomiyle ahlak arasındaki güçlü ilişkiyi vurgulayan İslam ahlak ekonomisi kavramsallaştırması öne çıkarılmaktadır. İslam ahlak ekonomisinin kuramsal temelleri dört ana aksiyom çerçevesinde ele alınmaktadır: tevhid, denge, özgür irade ve sorumluluk. Kur’an’daki birr ayeti ve İslam ahlak sistemine dayalı aksiyomlar, bireysel ve toplumsal düzeyde uyum ve adaleti sağlamada yol gösterici bir model sunmaktadır. Sonuç olarak, İslam ahlak ekonomisinin modern dünyada alternatif bir ekonomik paradigma olarak daha fazla görünürlük kazanması gerektiği sonucuna varılmıştır.
Ebussuud Efendi’nin Görüşleri ve Osmanlı Toprak-Vergi Rejimi Hakkında Bir Değerlendirme
Authors: Gürsoy Muhammed Emin
Published: December 2024

Bu çalışma, Ebussuud Efendi’nin fetvaları bağlamında Osmanlı toprak rejimi üzerine ekonomi-politik bir incelemedir. Osmanlı toprak rejiminin Ebussuud’un fetvalarının bir eseri mi olduğu yoksa Ebussuud’un fetvalarının Osmanlı sisteminin fıkhi zeminini oluşturmaktan ibaret mi olduğu kesin olmamakla birlikte, makalenin amacı arka planda yer alan iktisadi zihniyeti çözümlemektir. Bu çerçevede öncelikle klasik Hanefi fıkıh literatürüne ve toprak tartışmalarına iktisat tarihi bağlamında bakılmıştır akabinde Ebussuud’un fetvaları ve Osmanlı toprak rejimi aktarılmıştır. Söz konusu iktisadi zihniyeti doğrudan anlayabilmek için herhangi bir kaynak metin bulunmadığından tarihsel uygulamalardan ve Ebussuud’un görüşlerinden yola çıkılarak ekonomi-politik yorum yapılmaya çalışılmıştır. Son olarak, Ebussuud’un ve Osmanlı sisteminin İslam iktisadı içerisindeki yeri belirlenmeye ve bugünün dünyasında karşılık gelebileceği durumlar ve iktisaden taşıdığı muhtemel anlamlar değerlendirilmeye çalışılmıştır.
Chatbot Adoption Framework for Real-Time Customer Care Support
Authors: Nyongesa Geoffrey , Omieno Kelvin , Otanga Daniel
Published: December 2024

Computer programs or software that communicate with humans using natural language are referred to as chatbot applications. To provide customer care support services, there are no well-formulated guidelines for the implementation of artificial intelligence chatbots in Kenyan telecom companies. This study proposes an adoption framework for deploying artificially intelligent chatbots in Kenyan telecom companies. This was accomplished by determining the current level of the installation of chatbot apps in Kenya and identifying the primary metrics that might be used as indications for the dissemination of chatbots. A review of the earlier frameworks and models on technology adoption was conducted to determine the relevant metrics. A combination of research approaches was used in this study, with questionnaires and interview schedules being used to obtain quantitative and qualitative data, respectively. To examine qualitative data, content analysis was what was used. Using tables and charts, descriptive analysis was performed on the quantitative data, and the findings were presented. AI specialists working for Safaricom PLC and the Communications Authority of Kenya were the ideal candidates for this position. From the two different telecommunications companies, a sample was selected for the research study utilizing the Delphi approach. In this approach, the researcher reaches out to experts in the area of the study to gain in-depth knowledge of the issue being investigated because they serve as a guide on aspects to consider before using AI chatbots for customer support services provision. The results showed that chatbot applications are randomly implemented, the telecom firms are ready to adopt AI chatbots for customer service support. The adoption of the framework will help the telecom industry accept a reliable chatbot application which will in turn provide faster, accurate, and reliable service support to customers thus saving time and cutting costs. The framework that was built has the potential to serve as a guiding principle in the process of implementing chatbot technology within the telecom business settings. Further research should be done on the use of AI chatbots in other sectors like healthcare and agriculture.
Determination of some biological properties of the seeds of the Johnson grass (Sorghum halepense (L.) Pers.)
Authors: Şin Bahadır , Kadıoğlu İzzet , Yıldırım Celal
Published: December 2024

Dormancy is an important factor affecting seed germination and the emergence of weeds. In this study, the intensity of dormancy in freshly collected seeds of Sorghum halepense (L.) Pers. was determined, and various methods to break this dormancy were evaluated. These methods included sulfuric acid application, sanding, soaking in distilled water, folding method application, and gibberellic acid application. Additionally, the study aimed to determine the optimal, maximum, and minimum germination temperatures and assess seed germination at different burial depths. According to the experimental results, the most effective method for breaking dormancy was the application of 62.5% sulfuric acid for 30 minutes. The ideal germination temperature was found to be 30°C, with a germination rate of 87%. The minimum temperature for germination was 15°C (6% germination), and the maximum temperature was 40°C (48% germination). In terms of sowing depth, the highest germination rate was observed at a depth of 3 cm, where 50% of seeds germinated. It was also noted that the germination rate gradually decreased with increasing burial depth. The results of these experiments provide valuable information on effective methods for breaking seed dormancy in Sorghum halepense and offer insights into the optimal conditions for seed germination.
PEMBERDAYAAN IBU HAMIL TENTANG PEMILIHAN KONTRASEPSI PASCA PERSALINAN DI PUSKESMAS BELIMBING
Authors: Susilawati Dewi , Muthia Gina , Nilakesuma Nur Fadjri
Published: December 2024

Keluarga Berencana Pasca Persalinan (KBPP) dilakukan dalam 42 hari setelah melahirkan untuk mencegah kehamilan yang tidak diinginkan (KTD) dan menjaga jarak antar kehamilan minimal dua tahun. Tingginya adopsi kontrasepsi pasca melahirkan menunjukkan pentingnya KB dalam periode postpartum di Indonesia. Namun, cakupan metode kontrasepsi jangka panjang (MKJP) masih rendah, dipengaruhi oleh kurangnya pengetahuan, sikap negatif, dan rendahnya minat calon akseptor. Puskesmas Belimbing Kota Padang didapatkan banyak ibu hamil yang tidak mengetahui tentang pemilihan KBPP dan Tidak adanya media edukasi untuk kesejahteraan ibu hamil. Tujuan PkM adalah meningkatkan pengetahuan ibu hamil tentang KBPP serta adanya media edukasi yaitu booklet untuk pemberdayaan ibu hamil tentang pemilihan KBPP. Kegiatan dilaksanakan pada tanggal 17 Oktober 2024 kepada 5 pasang ibu hamil di Puskesmas Belimbing. Kegiatan ini dilakukan dua tahap. Tahap pertama tim pengabdian melakukan FGD kepada sasaran tentang pengalaman menggunakan alat kontasepsi. Tahapan kedua melakukan konseling kepada sasaran dengan media booklet tentang KBPP. Hasil kegiatan pelaksanaan Pk M terjadi peningkatan pengetahuan ibu hamil dari rata – rata 4,2 menjadi 8,4 tentang KBPP. Dengan demikian, metode FGD dan konseling menggunakan booklet ini dapat dianggap sebagai metode yang efektif untuk meningkatkan pengetahuan ibu hamil tentang KBPP sehingga cakupan KBPP dapat meningkat.
PENDAMPINGAN IMPLEMENTASI PEMBELAJARAN BERDIFERENSIASI PADA FASE A DI SDN PATIAN II DENGAN KURIKULUM MERDEKA
Authors: Punggeti Ratna Novita , Prijambodo Raden Firman Nurbudi , Matlubah Helliyatul
Published: December 2024

Tujuan dari kegiatan pengabdian masyarakat ini adalah untuk membantu guru-guru di SDN Patian II dalam menerapkan pembelajaran berdiferensiasi sesuai dengan Kurikulum Merdeka di Fase A (kelas 1 dan 2). Pembelajaran berdiferensiasi adalah metode yang bertujuan untuk memenuhi kebutuhan belajar individu siswa berdasarkan kesiapan, minat, dan profil belajar mereka. Diharapkan bahwa penerapan metode ini akan meningkatkan efektivitas proses pembelajaran, memaksimalkan potensi siswa, dan mendukung pencapaian profil siswa Pancasila. Kegiatan ini menggunakan pelatihan, pendampingan intensif, dan evaluasi implementasi. Kegiatan dimulai dengan menilai kebutuhan sekolah dan guru untuk mengetahui apa yang siswa pahami tentang pembelajaran berdiferensiasi. Kemudian, mereka diajarkan tentang ide-ide, prinsip, dan strategi pembelajaran diferensiasi, termasuk cara membuat RPP yang sesuai dengan kebutuhan siswa. Melalui observasi langsung dan diskusi reflektif, guru dibantu dalam menerapkan strategi pembelajaran diferensiasi di kelas mereka. Hasilnya mencakup peningkatan kemampuan guru untuk merancang dan menerapkan pembelajaran yang berbeda, yang ditunjukkan dengan peningkatan kualitas RPP, ide-ide baru untuk pembelajaran, dan pengelolaan kelas yang lebih sesuai dengan kebutuhan siswa. Siswa juga menunjukkan peningkatan partisipasi aktif dan hasil belajar yang lebih baik. Kegiatan ini meningkatkan kualitas pembelajaran di SDN Patian II. Namun, untuk terus menerapkan pembelajaran berdiferensiasi, diperlukan pelatihan tambahan, supervisi, dan evaluasi rutin. Oleh karena itu, diharapkan bahwa program ini akan berfungsi sebagai model pengembangan profesional guru yang dapat disesuaikan dengan kurikulum dan kebutuhan siswa.
The Duplex Nature of Indigeneity: Navigating Identity in the Ahuehuepan Diaspora
Authors: Schryer Frans J.
Published: December 2024

An examination of the impact of globalization on both sides of the US-Mexico border, focusing on people connected to the town Ahuehuepan in the state of Guerrero, tracing families, descendants, and people who locate the focus of their identity in a place they may have never seen.