bluuebunny/crossref_metadata_2025 huggingface dataset:
Recommendations for Cancer Epidemiologic Research in Understudied Populations and Implications for Future Needs
Authors: Martin Damali N. , Lam Tram Kim , Brignole Katy , Ashing Kimlin T. , Blot William J. , Burhansstipanov Linda , Chen Jarvis T. , Dignan Mark , Gomez Scarlett Lin , Martinez Maria Elena , Matthews Alicia , Palmer Julie R. , Perez-Stable Eliseo J. , Schootman Mario , Vilchis Hugo , Vu Alexander , Srinivasan Shobha
Published: April 2016

Medically underserved populations in the United States continue to experience higher cancer burdens of incidence, mortality, and other cancer-related outcomes. It is imperative to understand how health inequities experienced by diverse population groups may contribute to our increasing unequal cancer burdens and disparate outcomes. The National Cancer Institute convened a diverse group of scientists to discuss research challenges and opportunities for cancer epidemiology in medically underserved and understudied populations. This report summarizes salient issues and discusses five recommendations from the group, including the next steps required to better examine and address cancer burden in the United States among our rapidly increasing diverse and understudied populations. Cancer Epidemiol Biomarkers Prev; 25(4); 573–80. ©2016 AACR.

See all articles in this CEBP Focus section, “Multilevel Approaches to Addressing Cancer Health Disparities.”
Rapid Fiber-optic Raman Spectroscopy for Real-Time In Vivo Detection of Gastric Intestinal Metaplasia during Clinical Gastroscopy
Authors: Lin Kan , Wang Jianfeng , Zheng Wei , Ho Khek Yu , Teh Ming , Yeoh Khay Guan , Huang Zhiwei
Published: April 2016

We report a unique simultaneous fingerprint (FP) and high-wavenumber (HW) Raman spectroscopy technique coupled with a beveled fiber-optic Raman probe for improving in vivo detection of gastric intestinal metaplasia (IM)–precancerous lesions in real-time during clinical gastroscopy. A total of 4,520 high-quality in vivo FP/HW gastric Raman spectra (normal = 4,178; IM = 342) were acquired from 157 gastric patients undergoing endoscopic examination. Multivariate diagnostic algorithms based on principal components analysis and linear discriminant analysis together with the leave-one tissue site-out, cross-validation on in vivo tissue Raman spectra yield the diagnostic sensitivities of 89.3%, 89.3%, and 75.0%; specificities of 92.2%, 84.4%, and 82.0%; positive predictive values of 52.1%, 35.2%, and 28.4%; and negative predictive values of 98.9%, 98.8%, and 97.2%, respectively, by using the integrated FP/HW, FP, and HW Raman techniques for identifying IM from normal gastric tissue. Further, ROC curves generated show that the integrated FP/HW Raman technique gives the integration area under the ROC curve of 0.92 for IM classification, which is superior to either FP (0.89) or HW Raman (0.86) technique alone. This work demonstrates for the first time that the simultaneous FP/HW fiber-optic Raman spectroscopy has great potential to enhance early diagnosis of gastric precancer in vivo during routine endoscopic examination. Cancer Prev Res; 9(6); 476–83. ©2016 AACR.
Vascular Changes and Neurodegeneration in the Early Stages of Diabetic Retinopathy: Which Comes First?
Authors: Jonsson Karoline Boegeberg , Frydkjaer-Olsen Ulrik , Grauslund Jakob
Published: April 2016

Introduction: Neurodegeneration is an early component of diabetic retinopathy (DR). It is unclear whether neurodegeneration is an independent factor or a consequence of damaged retinal vasculature. The aims of this study were to review the literature concerning neurodegeneration in diabetic patients without or with early DR, and to examine whether neurodegeneration precedes visible vasculopathy in the pathogenesis of DR. Methods: A systematic literature search was performed to identify studies which used optical coherence tomography (OCT) or multifocal electroretinography (mfERG) to detect neurodegeneration in patients with no or mild DR as compared to healthy controls. Outcome measures were mean retinal thickness (RT), mean retinal nerve fiber layer (RNFL) thickness and ganglion cell layer (GCL) thickness. Also, mfERG amplitude and implicit time were analyzed. Results: Eleven studies which used mfERG and/or OCT to detect neurodegeneration were included. Two OCT studies found significant thinning of RT, 2 found thinning of RNFL, whereas 1 found thickening of RT, RNFL and GCL in patients without DR. Two mfERG studies found a significant delay of implicit time in the same patient group. Retinal thinning and delay of implicit time were also detected in patients with mild DR. Conclusion: Retinal neurodegeneration is an early component of DR, which can precede visible vasculopathy.
Turritopsis fascicularis Fraser, 1943 (Cnidaria: Hydrozoa): redescription and discussion of its phylogenetic position within the genus
Authors: MIGLIETTA MARIA PIA
Published: April 2016

Turritopsis fascicularis Fraser, 1943 was first described off Alligator Reef, Florida, USA, at a depth of 216 m. Presumably a deep-sea species, its validity has often been questioned due to the scarcity of available records. In this paper, T. fascicularis is re-described from some mature colonies from the upper slope of the Gulf of Mexico. Furthermore, new pictures of the colony, polyps, and medusa buds, are provided. A ~600bp sequence of the large ribosomal subunit of the mitochondrial RNA (lsu-rRNA, 16S), also known as the Hydrozoan barcoding molecule, is used for the first time to confirm the validity of T. fascicularis as a species, and analyze its phylogenetic position within the genus Turritopsis.
Evaluating Simulated Fraction of Attributable Risk Using Climate Observations
Authors: Lott Fraser C. , Stott Peter A.
Published: April 2016

Although it is critical to assess the accuracy of attribution studies, the fraction of attributable risk (FAR) cannot be directly assessed from observations since it involves the probability of an event in a world that did not happen, the “natural” world where there was no human influence on climate. Instead, reliability diagrams (usually used to compare probabilistic forecasts to the observed frequencies of events) have been used to assess climate simulations employed for attribution and by inference to evaluate the attribution study itself. The Brier score summarizes this assessment of a model by the reliability diagram. By constructing a modeling framework where the true FAR is already known, this paper shows that Brier scores are correlated to the accuracy of a climate model ensemble’s calculation of FAR, although only weakly. This weakness exists because the diagram does not account for accuracy of simulations of the natural world. This is better represented by two reliability diagrams from early and late in the period of study, which would have, respectively, less and greater anthropogenic climate forcing. Two new methods are therefore proposed for assessing the accuracy of FAR, based on using the earlier observational period as a proxy for observations of the natural world. It is found that errors from model-based estimates of these observable quantities are strongly correlated with errors in the FAR estimated in the model framework. These methods thereby provide new observational estimates of the accuracy in FAR.
Religious Authorities in the Military and Civilian Control
Authors: Levy Yagil
Published: April 2016

This article takes a step toward filling the gap in the scholarly literature by examining the impact of religious intervention in the military on civil-military relations. Using the case of Israel, I argue that although the subordination of the Israeli military to elected civilians has remained intact, and the supreme command has been mostly secular, external religious authorities operate within the formal chain of command and in tandem with the formal authorities, managing the military affairs. This religious influence is apparent in three major domains: (1) the theological influence on military deployment, (2) the exclusion of women from equal participation in military service, and (3) the role expansion of the Military Rabbinate as a quasi-state agency and its reflection in the socialization of secular soldiers and the development of alternative military ethics. Consequently, extra-institutional control of the military is at work.
Neighbourhood immigrant concentration effects on migrant and native youth’s educational commitments, an enquiry into personality differences
Authors: Nieuwenhuis Jaap , Hooimeijer Pieter , van Ham Maarten , Meeus Wim
Published: April 2016

In the literature examining neighbourhood effects on educational outcomes, the socialisation mechanism is usually investigated by looking at the association between neighbourhood characteristics and educational attainment. The step in between, that adolescents actually internalise educational norms held by residents, is often assumed. We attempt to fill this gap by looking at how the internalisation of educational norms (commitments) is influenced by neighbourhoods’ immigrant concentration. We investigate this process for both migrant and native youth, as both groups might be influenced differently by immigrant concentrations. To test our hypothesis we used longitudinal panel data with five waves (N = 4255), combined with between-within models which control for a large portion of potential selection bias. These models have an advantage over naïve OLS models in that they predict the effect of change in neighbourhood characteristics on change in educational commitment, and therefore offer a more dynamic approach to modelling neighbourhood effects. Our results show that living in neighbourhoods with higher proportions of immigrants increases the educational commitments of migrant youth compared to living in neighbourhoods with lower proportions. Besides, we find that adolescents with a resilient personality experience less influence of the neighbourhood context on educational commitments than do adolescents with non-resilient personalities.
Agreement Between HEDIS Performance Assessments in the VA and Medicare Advantage
Authors: Trivedi Amal N. , Wilson Ira B. , Charlton Mary E. , Kizer Kenneth W.
Published: April 2016

Medicare Advantage (MA) plans and the Veterans Affairs (VA) health care system assess quality of care using standardized Healthcare Effectiveness Data and Information Set (HEDIS) performance measures. Little is known, however, about the relative accuracy of quality indicators for persons receiving care in more than one health care system. Among Veterans dually enrolled in an MA plan, we examined the agreement between MA and VA HEDIS assessments. Our study tested the hypothesis that private health plans underreport quality of care relative to a fully integrated delivery system utilizing a comprehensive electronic health record. Despite assessing the same individuals using identical measure specifications, reported VA performance was significantly better than reported MA performance for all 12 HEDIS measures. The VA’s performance advantage ranged from 9.8% (glycosylated hemoglobin [HbA1c] < 7.0% in diabetes) to 54.7% (blood pressure < 140/90 mm Hg in diabetes). The overall agreement between VA and MA HEDIS assessments ranged from 38.5% to 62.6%. Performance rates derived from VA and MA aggregate data were 1.6% to 14.3% higher than those reported by VA alone. This analysis suggests that neither MA plans nor the VA fully capture quality of care information for dually enrolled persons. However, the VA’s system-wide electronic health record may allow for more complete capture of quality information across multiple providers and settings.
Reconsidering Power and Legitimacy in Technical Communication
Authors: Henning Teresa , Bemer Amanda
Published: April 2016

This article considers how issues of power and legitimacy in technical communication are connected to clearly defining what a technical communicator does. An articulation of what technical communicators do can grant the field power in presenting a united front to employers with respect to the value technical communicators bring to the workplace. So as to leverage the power and legitimacy associated with articulating what technical communicators do, this article reviews and revises the Bureau of Labor Statistics Occupational Outlook Handbook (OOH)’s definition of technical communicator. To effectively revise the OOH’s definition, this article reviews academic and practitioner scholarship in technical communication and the administration of technical and professional writing programs. It demonstrates that concerns about practical skills, conceptual skills, and flexibility are related to legitimacy and power. These concerns can be used as criteria to evaluate and revise the OOH’s definition of technical communicator. In closing, the article discusses the benefits associated with the revised definition and how these benefits are related to issues of power and legitimacy in the field.
Is Military Employment Fair? Application of Social Comparison Theory in a Cross-National Military Sample
Authors: Goldenberg Irina , Andres Manon , Resteigne Delphine
Published: April 2016

Although military and civilian personnel work closely together in defense organizations, they are subject to different human resources practices and conditions of service. Assessments of military personnel along a range of job characteristics are examined to identify areas in which they assess themselves as “better or worse off” than their civilian counterparts, and how these comparisons relate to perceptions of fairness using data from Belgium, Canada, and the Netherlands. Military personnel reported meaningfulness/support aspects (e.g., meaningful work) as similar for military and civilian personnel, indicated that negative impacts (e.g., risk of injury) were greater for military, and perceived variability in instrumental benefits (e.g., pay, advancement). Upward social comparison (i.e., seeing oneself as worse off) was related to lower perceived fairness, whereas downward social comparison was related to higher perceived fairness. This research informs mechanisms for promoting perceptions of fairness and enhancing military–civilian personnel relations in defense establishments.
Exploring Black Immigrants’ and Nonimmigrants’ Understanding of “Acting Black” and “Acting White”
Authors: Thelamour Barbara , Johnson Deborah J.
Published: April 2016

Immigrant and nonimmigrant Black adolescents’ perceptions of “acting Black” and “acting White” were compared using a concurrent mixed-methods approach. Using the Maryland Adolescent Development in Context Study data set, 39 second-generation African and Caribbean adolescent immigrants and a matched set of 39 nonimmigrant Black peers responded to the question “What does it mean to act Black/White?” Their responses were examined for differences and change over time. Quantitative analyses revealed that all Black youth shifted in their perspectives of acting White and acting Black but immigrant youth differed significantly from their nonimmigrant counterparts. Analysis of secondary qualitative text further highlighted respondents’ development and change at Time 2. These results underscore a racial cultural orientation process under the tridimensional model that acknowledges Black immigrants’ acculturation to African American culture in the United States.
Blood–brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice
Authors: Stranahan Alexis M , Hao Shuai , Dey Aditi , Yu Xiaolin , Baban Babak
Published: April 2016

Accumulating evidence indicates that obesity accelerates the onset of cognitive decline. While mechanisms are still being identified, obesity promotes peripheral inflammation and increases blood–brain barrier (BBB) permeability. However, no studies have manipulated vascular permeability in obesity to determine whether BBB breakdown underlies memory deficits. Protein kinase Cβ (PKCβ) activation destabilizes the BBB, and we used a PKCβ inhibitor (Enzastaurin) to block BBB leakiness in leptin receptor-deficient (db/db) mice. Enzastaurin reversed BBB breakdown in db/db mice and normalized hippocampal function without affecting obesity or metabolism. Flow cytometric analysis of forebrain mononuclear cells (FMCs) from db/db mice revealed macrophage infiltration and induction of the activation marker MHCII in microglia and macrophages. Enzastaurin eliminated macrophage infiltration and MHCII induction, and protein array profiling revealed parallel reductions in IL1β, IL6, MCP1, and TNFα. To investigate whether these signals attract peripheral monocytes, FMCs from Wt and db/db mice were plated below migration inserts containing peritoneal macrophages. Peritoneal macrophages from db/db mice exhibit increases in transmigration that were blocked by recombinant IL1RA. These studies indicate that BBB breakdown impairs cognition in obesity and diabetes by allowing macrophage infiltration, with a potential role for IL1β in trafficking of peripheral monocytes into the brain.
Technology enabled learning of metal forming processes for engineering graduates using virtual simulation lab
Authors: Sharma Rahul Swarup
Published: April 2016

Metal forming process is a widely used manufacturing process mainly for its economy, dimensional precision, and improved mechanical properties of the formed product. Real-time laboratory experiments are key to mechanical engineering course of metal forming. Lack of available capital in small engineering institutions constraints huge investments over machinery and necessary technologies. An interactive metal forming simulation lab is developed (i) having web-based global access to everyone (ii) with user friendly interface to move seamlessly and find topics (iii) enhancing learning by CAD simulations of metal forming processes (iv) to explore what-if situations experimenting over interactive simulation benches and (v) automatically scored e-quizzes for testing knowledge. This work helps amateur mechanical engineers and mechanical engineering undergraduate students of second, third, fourth, and fifth semesters, respectively, in learning and understanding of metal forming processes and concepts, allowing analysis and visualization of temperature changes, microstructure change, etc. This can be accessed through web address http://msvs-dei.vlabs.ac.in/ and contains over 200 modules. Each module is supported by adequate theory to reduce time and effort needed to understand different metal forming setups, various process parameters, materials, and equipments involved in the processes and provides interactive learning environment.
The emergence of materialism in geography: Belonging and being, space and place, sea and land
Authors: Nieuwenhuis Marijn
Published: April 2016

This article provides an analysis and discussion of the concept of emergence in the context of the materialist turn in the discipline of geography. Etymologically, the word emergence is said to describe that which ‘becomes visible after being concealed’ but is also described as an ‘unforeseen occurrence; a state of things unexpectedly arising, and demanding immediate attention’ ( Oxford English Dictionary). The concept is in this article analysed through the lens of two distinct traditions of thought. The first is commonly associated with relational ontologies of becoming. The second finds its ‘roots’ and is ‘grounded’ in a metaphysical analysis of the ontology of being. Divisions between these two schools of thought are characterized by conceptual differences over concepts of space and place, difference and sameness, process and constancy, land and sea, etc.

These differences are not restricted to the conceptual level but also bear political relevance. The article makes this explicit by looking at the theme of emergence, which can be understood either as a relational process of change or as a force of stability and a quest for origins. The former suggests an understanding of materiality that is always in a state of becoming, while the latter infers an approach to materiality that is static and permanent. The article critiques both of these approaches: the relational one for its lack of place, the metaphysical one for its reification of place and its omission of relationality. The article finishes with a call for an elemental ontological approach to place. Rather than abandoning place (Being) for the sake of space (Becoming), the material turn should seek ways to broaden understandings of place.
Ethnic Variables and Negative Life Events as Predictors of Depressive Symptoms and Suicidal Behaviors in Latino College Students
Authors: Chang Edward C. , Yu Elizabeth A. , Yu Tina , Kahle Emma R. , Hernandez Viviana , Kim Jean M. , Jeglic Elizabeth L. , Hirsch Jameson K.
Published: April 2016

In the present study, we examined ethnic variables (viz., multigroup ethnic identity and other group orientation) along with negative life events as predictors of depressive symptoms and suicidal behaviors in a sample of 156 (38 male and 118 female) Latino college students. Results of conducting hierarchical regression analyses indicated that the set of ethnic variables accounted for significant variance in both depressive symptoms and suicidal behaviors. The inclusion of negative life events was found to account for significant additional variance in both outcomes, beyond what was accounted for by ethnic variables. Interestingly, beyond main effects, results indicated a significant Other Group Orientation × Negative Life Events interaction effect to account for additional variance in depressive symptoms and suicidal behaviors. Some implications of the present findings are discussed, including the potential value for Latinos to broaden their attitudes and interactions with other ethnic groups.
Are elite cricketers more prone to suicide? A psychological autopsy study of Test cricketer suicides
Authors: Shah Ajit , Sava-Shah Shrenik , Wijeratne Chanaka , Draper Brian
Published: April 2016

Objectives:

It has been hypothesised that the very nature of the game predisposes elite cricketers to higher rates of suicide.

Aim:

We aim to estimate the suicide rate of male Test cricketers and to determine the reasons for suicide.

Methods:

The suicide rate in male Test cricketers was determined. A psychological autopsy was conducted using published biographical data.

Results:

Twenty suicides amongst 2794 male Test cricketers from 1877 to 2014 yielded a suicide rate of 715.4 per 100,000 for that period. Health, financial and relationship issues were prominent; depression and alcohol misuse were common.

Conclusions:

Most suicides in Test cricketers occurred post-retirement in mid to late life with similar correlates to those found in the general male population. The idiosyncrasies of cricket are unlikely to contribute to suicide; however, the post-retirement welfare of Test cricketers should remain a focus of concern and the greater supports available to contemporary Test cricketers needs to extend beyond retirement.
Development of a consensus reverse transcription PCR assay for the specific detection of tortoise picornaviruses
Authors: Marschang Rachel E. , Ihász Katalin , Kugler Renáta , Lengyel György , Fehér Enikő , Marton Szilvia , Bányai Krisztián , Aqrawi Tara , Farkas Szilvia L.
Published: April 2016

Picornaviruses (PVs) of different terrestrial tortoise species, previously designated as Virus “X,” have been frequently detected from various tissues by virus isolation in Terrapene heart cell culture as the preferred laboratory method for diagnosis. Here, we describe the development of 2 diagnostic reverse transcription (RT)-PCR–based assays for the identification and characterization of tortoise PVs belonging to the tentative genus Topivirus. To test the novel diagnostic systems, PVs were isolated from swab and tissue samples collected in Germany, Italy, and Hungary between 2000 and 2013. All 25 tested isolates gave positive results with both novel consensus primer sets. Sequencing of the amplified products confirmed that all studied viruses were members of the new proposed genus Topivirus. Phylogenetic analyses clearly distinguished 2 lineages within the genus. Based on sequence analysis, no association was observed between the geographic distribution and genetic relatedness. Furthermore, no strict host specificity was indicated. The PCR-based diagnosis may provide a time-saving and sensitive method to detect tortoise PVs, and evaluation of PV presence in these animals may help control virus spread.
Exploring Nurse Communication About Spirituality
Authors: Wittenberg Elaine , Ragan Sandra L. , Ferrell Betty
Published: April 2016

Objective:

Although spiritual care is considered one of the pillars of palliative care, many health-care providers never receive formal training on how to communicate about spirituality with patients and families. The aim of this study was to explore the spiritual care experiences of oncology nurses in order to learn more about patient needs and nurse responses.

Methods:

A survey was circulated at a communication training course for oncology nurses in June 2015. Nurses recalled a care experience that included the initiation of a spiritual care topic and their response to the patient/family. Data were analyzed using thematic analysis.

Results:

Nurses reported that communication about spirituality was primarily initiated by patients, rather than family members, and spiritual topics commonly emerged during the end of life or when patients experienced spiritual distress. Nurses’ experiences highlighted the positive impact spiritual conversations had on the quality of patient care and its benefit to families. Spiritual communication was described as an important nursing role at the end of patients’ lives, and nonverbal communication, listening, and discussing patients’ emotions were emphasized as important and effective nurse communication skills during spiritual care conversations. Approximately one-third of nurses in the sample reported sharing their own personal spiritual or religious backgrounds with patients, and they reported that these sharing experiences strengthened their own faith.

Conclusion:

It is evident that patients want to discuss spiritual topics during care. Study findings illustrate the need to develop a spiritual communication curriculum and provide spiritual care communication training to clinicians.
Applying Organizational Learning Research to Accountable Care Organizations
Authors: Nembhard Ingrid M. , Tucker Anita L.
Published: April 2016

To accomplish the goal of improving quality of care while simultaneously reducing cost, Accountable Care Organizations (ACOs) need to find new and better ways of providing health care to populations of patients. This requires implementing best practices and improving collaboration across the multiple entities involved in care delivery, including patients. In this article, we discuss seven lessons from the organizational learning literature that can help ACOs overcome the inherent challenges of learning how to work together in radically new ways. The lessons involve setting expectations, creating a supportive culture, and structuring the improvement efforts. For example, with regard to setting expectations, framing the changes as learning experiences rather than as implementation projects encourages the teams to utilize helpful activities, such as dry runs and pilot tests. It is also important to create an organizational culture where employees feel safe pointing out improvement opportunities and experimenting with new ways of working. With regard to structure, stable, cross-functional teams provide a powerful building block for effective improvement efforts. The article concludes by outlining opportunities for future research on organizational learning in ACOs.
Family Feuds Are Forever
Authors: Giorgio Grace A.
Published: April 2016

A follow-up reflection on the writing of “Family Feuds are Forever” explores how writing autoethnographically is not an innocent practice. When we write, we become vulnerable to others’ readings of our words and lived experiences. Yet, as writers of social science texts, we welcome this vulnerability, and in doing so, we discard our innocence. We create interpretations of events and a record for ourselves, and others, that are subject to outside and inside scrutiny. This reflection explores how writing autoethnographically as in “Family Feuds are Forever” challenges us to be ethical with ourselves and others.
The Norwegian Translation of the Adult Attention-Deficit/Hyperactivity Disorder Quality of Life Scale: Validation and Assessment of QoL in 313 Adults With ADHD
Authors: Gjervan Bjørn , Torgersen Terje , Hjemdal Odin
Published: April 2016

Objective: The aim of the study was to validate the Norwegian version of the Adult Attention-Deficit/Hyperactivity Disorder Quality of Life (AAQoL) scale and to explore Quality of Life (QoL) and functional outcomes in adults with ADHD. Method: A total of 313 adults with ADHD participated in the study. Data were collected from medical records and self-report questionnaires. Confirmatory factor analysis was performed to assess the model fit of the translated AAQoL. Chi-square statistics and t tests were used to investigate sample characteristics. Results: The analyses showed acceptable model fit between data and the model. Chi square = 863.179 (371 df, p < .0000), root mean square error of approximation (RMSEA) = 0.069 (90% confidence interval [CI]), comparative fit index (CFI) = 0.873, and Tucker–Lewis index (TLI) = 0.821. Cronbach’s alpha range for the scales was .761 to .869. The sample was characterized by poor QoL and impairment. Conclusion: The translated AAQoL is showing good initial indications of validity with acceptable psychometric properties in the sample. ADHD was associated with impairments in QoL, symptoms, and functional outcomes.
Ideal Body Size as a Mediator for the Gender-Specific Association Between Socioeconomic Status and Body Mass Index
Authors: Yepes Maryam , Maurer Jürgen , Stringhini Silvia , Viswanathan Barathi , Gedeon Jude , Bovet Pascal
Published: April 2016

Background. While obesity continues to rise globally, the associations between body size, gender, and socioeconomic status (SES) seem to vary in different populations, and little is known on the contribution of perceived ideal body size in the social disparity of obesity in African countries. Purpose. We examined the gender and socioeconomic patterns of body mass index (BMI) and perceived ideal body size in the Seychelles, a middle-income small island state in the African region. We also assessed the potential role of perceived ideal body size as a mediator for the gender-specific association between SES and BMI. Method. A population-based survey of 1,240 adults aged 25 to 64 years conducted in December 2013. Participants’ BMI was calculated based on measured weight and height; ideal body size was assessed using a nine-silhouette instrument. Three SES indicators were considered: income, education, and occupation. Results. BMI and perceived ideal body size were both higher among men of higher versus lower SES ( p < .001) but lower among women of higher versus lower SES ( p < .001), irrespective of the SES indicator used. Multivariate analysis showed a strong and direct association between perceived ideal body size and BMI in both men and women ( p < .001) and was consistent with a potential mediating role of perceived ideal body size in the gender-specific associations between SES and BMI. Conclusion. Our study emphasizes the importance of gender and socioeconomic differences in BMI and ideal body size and suggests that public health interventions that promote perception of healthy weight could help mitigate SES-related disparities in BMI.
Early childhood music education research: An overview
Authors: Young Susan
Published: April 2016

This article offers a short commentary on the “state of play” in early childhood music education research to accompany the articles published in this special issue. It provides an international overview of recent research trends in this field, with examples drawn from Europe, the Americas, Asia, the Middle East, East and South Africa and Australia.
Acceptability of vaccination against HIV: A mapping of Togolese people’s positions
Authors: Kpanake Lonzozou , Gbandey Sadji , Sorum Paul Clay , Mullet Etienne
Published: April 2016

In anticipation of a future HIV vaccine, we mapped the different personal positions regarding HIV vaccination of people in Togo. In early 2014, 363 adults indicated their willingness to receive a future HIV vaccine under different conditions varying as a function of five factors: perceived susceptibility to HIV, vaccine effectiveness, perceived severity of AIDS, vaccine cost, and family’s influence. We found five qualitatively different positions: unconditional acceptance (49%), depends on cost/effectiveness ratio (20%), depends on cost (18%), total indecision (10%), and complete reluctance (3%). Accordingly, HIV vaccination strategies in Togo and elsewhere in Africa need to be multifaceted and tailored.
Stylometric analysis for case linkage of Japanese communications from criminals
Authors: Zaitsu Wataru , Jin Mingzhe
Published: April 2016

The effectiveness of stylometric analysis of Japanese communications from criminals for linking crimes through text mining was investigated. Forty letters of threats and blackmails in the ‘ Glico–Morinaga’ case were analyzed as originals. These original letters were compared with four copycat letters in which the suspect in the ‘ Kuroko’s Basketball’ (KB) case imitated the writings in the ‘ Glico–Morinaga’ (GM) case. We focused on four stylometric features in the writings: (a) bigram of characters, (b) bigram of parts-of-speech, (c) unigram of vocabularies, and (d) frequency of use of Kanji, Hiragana, and Katakana. We analyzed these stylometric features using correspondence analysis and hierarchical cluster analysis. The results showed that all the ‘KB’ texts gathered in the same crowd or cluster, which was separate from those including the ‘GM’ texts. Moreover, the ‘GM’ texts were not consistently distant from each other. This study suggested that stylometric analysis could distinguish between original and copycat communications, and appropriately link crimes on the basis of written information.
Between coordination and regulation: Finding the governance in Internet governance
Authors: Hofmann Jeanette , Katzenbach Christian , Gollatz Kirsten
Published: April 2016

Following recent theoretical contributions, this article suggests a new approach to finding the governance in Internet governance. Studies on Internet governance rely on contradictory notions of governance. The common understanding of governance as some form of deliberate steering or regulation clashes with equally common definitions of Internet governance as distributed modes of ordering. Drawing on controversies in the broader field of governance and regulation studies, we propose to resolve this conceptual conundrum by grounding governance in mundane activities of coordination. We define governance as reflexive coordination – focusing on those ‘critical moments’, when routine activities become problematic and need to be revised, thus, when regular coordination itself requires coordination. Regulation, in turn, can be understood as targeted public or private interventions aiming to influence the behaviour of others. With this distinction between governance and regulation, we offer a conceptual framework for empirical studies of doing Internet governance.
Tor, what is it good for? Political repression and the use of online anonymity-granting technologies
Authors: Jardine Eric
Published: April 2016

Why do people use anonymity-granting technologies when surfing the Internet? Anecdotal evidence suggests that people often resort to using online anonymity services, like the Tor network, because they are concerned about the possibility of their government infringing their civil and political rights, especially in highly repressive regimes. This claim has yet to be subject to rigorous cross-national, over time testing. In this article, econometric analysis of newly compiled data on Tor network usage from 2011 to 2013 shows that the relationship between political repression and the use of the Tor network is U-shaped. Political repression drives usage of Tor the most in both highly repressive and highly liberal contexts. The shape of this relationship plausibly emerges as a function of people’s opportunity to use Tor and their need to use anonymity-granting technologies to express their basic political rights in highly repressive regimes.
The Experience and Persistence of College Students in STEM Majors
Authors: Xu Yonghong Jade
Published: April 2016

In this study, an online survey was constructed based on the extant literature on college student success. The survey was used to collect data from a sample of college students in science, technology, engineering, and math (STEM) majors in order to examine their learning experiences and to identify the factors that may influence their persistence to degree completion. The findings support the theoretical modeling of the academic and social aspects of student college experience. Nonetheless, it is the institutional conditions, particularly the quality of academic program and faculty teaching and accessibility, which dominate the STEM students’ college experience and their persistence in academic major and to graduation. Therefore, it is critical for academic institutions to invest in a supportive learning environment by emphasizing quality teaching, accessible academic advising, and related functions in order to successfully engage STEM students in college education and increase their likelihood of degree completion.
Human Trafficking in Ethiopia: A Scoping Review to Identify Gaps in Service Delivery, Research, and Policy
Authors: Beck Dana C. , Choi Kristen R. , Munro-Kramer Michelle L. , Lori Jody R.
Published: April 2016

The purpose of this review is to integrate evidence on human trafficking in Ethiopia and identify gaps and recommendations for service delivery, research and training, and policy. A scoping literature review approach was used to systematically search nursing, medical, psychological, law, and international databases and synthesize information on a complex, understudied topic. The search yielded 826 articles, and 39 met the predetermined criteria for inclusion in the review. Trafficking in Ethiopia has occurred internally and externally in the form of adult and child labor and sex trafficking. There were also some reports of organ trafficking and other closely related human rights violations, such as child marriage, child soldiering, and exploitative intercountry adoption. Risk factors for trafficking included push factors (poverty, political instability, economic problems, and gender discrimination) and pull factors (demand for cheap labor). Trafficking was associated with poor health and economic outcomes for victims. Key recommendations for service delivery, research and training, and policy are identified, including establishing comprehensive services for survivor rehabilitation and reintegration, conducting quantitative health outcomes research, and reforming policy around migration and trafficking. Implementing the recommendations identified by this review will allow policy makers, researchers, and practitioners to take meaningful steps toward confronting human trafficking in Ethiopia.
How the Ghosts Stole All the Kisses: Slow Modernity
Authors: Wilkinson Alex
Published: April 2016

We are getting faster, or so we have been led to believe. Planes, trains, and automobiles—alongside the substrates of online modernity—have seemed to suggest to us that the world is a place we are constantly in need of catching up with. In turn, partially in response to institutional demands on productivity, some academics have suggested slow methods in research.1Yet, what if we were never fast in the first place? What if the things and atmospheres of Western industrial modernity actually produce slow ontologies of feeling as we traverse space and place? Straddling history, literature, and (auto)ethnographic attunements to emotions and society, this article attempts to suggest there is a modernity which is slow—an “endless mastication”—in which we, as both subject and subjects, are chewed-up and spat out amid the endlessly deferring signs of the presence and absence of meaning in social space.
Computationally efficient visual–inertial sensor fusion for Global Positioning System–denied navigation on a small quadrotor
Authors: Liu Chang , Prior Stephen D , Teacy WT Luke , Warner Martin
Published: April 2016

Because of the complementary nature of visual and inertial sensors, the combination of both is able to provide fast and accurate 6 degree-of-freedom state estimation, which is the fundamental requirement for robotic (especially, unmanned aerial vehicle) navigation tasks in Global Positioning System–denied environments. This article presents a computationally efficient visual–inertial fusion algorithm, by separating orientation fusion from the position fusion process. The algorithm is designed to perform 6 degree-of-freedom state estimation, based on a gyroscope, an accelerometer and a monocular visual-based simultaneous localisation and mapping algorithm measurement. It also recovers the visual scale for the monocular visual-based simultaneous localisation and mapping. In particular, the fusion algorithm treats the orientation fusion and position fusion as two separate processes, where the orientation fusion is based on a very efficient gradient descent algorithm, whereas the position fusion is based on a 13-state linear Kalman filter. The elimination of the magnetometer sensor avoids the problem of magnetic distortion, which makes it a power-on-and-go system once the accelerometer is factory calibrated. The resulting algorithm shows a significant computational reduction over the conventional extended Kalman filter, with competitive accuracy. Moreover, the separation between orientation and position fusion processes enables the algorithm to be easily implemented onto two individual hardware elements and thus allows the two fusion processes to be executed concurrently.
A mixed-method outcome evaluation of a specialist Alcohol Hospital Liaison Team
Authors: McGeechan Grant J , Wilkinson Kirsty G , Martin Neil , Wilson Lynn , O’Neill Gillian , Newbury-Birch Dorothy
Published: April 2016

Aims:

To evaluate the effectiveness of an Alcohol Hospital Liaison Team at reducing alcohol-specific hospital attendances and admissions.

Methods:

In a mixed-method evaluation, 96 patients who accessed the team were monitored using data for alcohol-specific hospital attendances and Accident and Emergency (A&E) admissions before, during, and after engaging with the team. A feedback survey was sent to patients and a focus group was held with staff from the team to identify barriers and facilitators to the successful delivery of this service.

Results:

No differences were observed when looking at alcohol admissions or A&E attendances before patients engaged with the service to those after discharge. While hospital admissions decreased slightly and A&E attendances increased slightly, these differences were not significant. Hospital admissions and A&E attendances increased significantly during engagement with the service. The focus group identified confusion over who should be delivering brief interventions and that the team was holding onto patients for too long.

Conclusion:

The results of this evaluation demonstrated that this team was not effective at reducing alcohol attendances or admissions due to a number of factors. Policy makers should make note of the barriers to effectiveness highlighted in this article, before commissioning alcohol care teams in the future.
Workplace Discrimination Is Associated With Alcohol Abuse Among Ethnically Diverse Hospital Staff
Authors: Thrasher Angela D. , Wells Anita M. , Spencer S. Melinda , Cofie Leslie , Yen Irene H.
Published: April 2016

Research suggests that workplace discrimination plays a role in absenteeism, productivity, and turnover. A link among workplace discrimination, mental health, and health disparities may also exist. The purpose of this study was to determine whether self-reported workplace discrimination is associated with alcohol abuse among hospital workers. Cross-sectional analysis of baseline data collected from a prospective cohort study of workers in two healthcare institutions ( n = 664) was conducted. Workplace discrimination in the previous 12 months was reported by 14% ( n = 91) of participants who were four times more likely to score higher on likely alcohol abuse than their peers. White participants who reported any discrimination were more likely to score higher on likely alcohol abuse than racial/ethnic minority participants who reported any discrimination. Given a diversifying workforce, further research is needed on how workplace discrimination contributes to stress and maladaptive coping, and ultimately health disparities.
Minicircle DNA-mediated endothelial nitric oxide synthase gene transfer enhances angiogenic responses of bone marrow-derived mesenchymal stem cells
Authors: Bandara Nadeeka , Gurusinghe Saliya , Chen Haiying , Chen Shuangfeng , Wang Le-xin , Lim Shiang Y. , Strappe Padraig
Published: April 2016

Background

Non-viral-based gene modification of adult stem cells with endothelial nitric oxide synthase (eNOS) may enhance production of nitric oxide and promote angiogenesis. Nitric oxide (NO) derived from endothelial cells is a pleiotropic diffusible gas with positive effects on maintaining vascular tone and promoting wound healing and angiogenesis. Adult stem cells may enhance angiogenesis through expression of bioactive molecules, and their genetic modification to express eNOS may promote NO production and subsequent cellular responses.

Methods

Rat bone marrow-derived mesenchymal stem cells (rBMSCs) were transfected with a minicircle DNA vector expressing either green fluorescent protein (GFP) or eNOS. Transfected cells were analysed for eNOS expression and NO production and for their ability to form in vitro capillary tubules and cell migration. Transcriptional activity of angiogenesis-associated genes, CD31, VEGF-A, PDGFRα, FGF2, and FGFR2, were analysed by quantitative polymerase chain reaction.

Results

Minicircle vectors expressing GFP (MC-GFP) were used to transfect HEK293T cells and rBMSCs, and were compared to a larger parental vector (P-GFP). MC-GFP showed significantly higher transfection in HEK293T cells (55.51 ± 3.3 %) and in rBMSC (18.65 ± 1.05 %) compared to P-GFP in HEK293T cells (43.4 ± 4.9 %) and rBMSC (15.21 ± 0.22 %). MC-eNOS vectors showed higher transfection efficiency (21 ± 3 %) compared to P-eNOS (9 ± 1 %) and also generated higher NO levels. In vitro capillary tubule formation assays showed both MC-eNOS and P-eNOS gene-modified rBMSCs formed longer (14.66 ± 0.55 mm and 13.58 ± 0.68 mm, respectively) and a greater number of tubules (56.33 ± 3.51 and 51 ± 4, respectively) compared to controls, which was reduced with the NOS inhibitor L-NAME. In an in vitro wound healing assay, MC-eNOS transfected cells showed greater migration which was also reversed by L-NAME treatment. Finally, gene expression analysis in MC-eNOS transfected cells showed significant upregulation of the endothelial-specific marker CD31 and enhanced expression of VEGFA and FGF-2 and their corresponding receptors PDGFRα and FGFR2, respectively.

Conclusions

A novel eNOS-expressing minicircle vector can efficiently transfect rBMSCs and produce sufficient NO to enhance in vitro models of capillary formation and cell migration with an accompanying upregulation of CD31, angiogenic growth factor, and receptor gene expression.