bluuebunny/crossref_metadata_2025 huggingface dataset:
Nutritional and hematological profile of children with severe acute malnutrition rehabilitated with or without vitamin B12
Authors: Khanna Siddharth , Kumar Praveen , Sharma Sunita , Chandra Jagdish , Sinha Rajesh
Published: January 2022

Background: Aim of the study was to study the effect of vitamin B12 supplementation in children with severe acute malnutrition (SAM).Methods: A total of 100 children were enrolled in the study in two different time frames.  Group A consisted of 50 children with SAM enrolled from November 2016 to May 2017 and managed as per existing national protocol for facility-based SAM management while group B consisted of 50 children enrolled from June 2017 to Dec 2017 who were tested for vitamin B12 deficiency on admission and supplemented with vitamin B12 in presence of vitamin B12 deficiency hematological and anthropometric parameters of both groups were compared at 12 weeks of rehabilitation.  Results: At 12±1 weeks, 38% children from group A and 24% from group B were still anemic (p=0.13). No one from either group had folic acid deficiency while deficiency of vitamin B12 was present in 14% and 6% cases in group A and group B respectively (p>0.05). Mean weight gain at 12±1 weeks, in group A and non-supplemented sub-group of group B was comparable (p>0.59). However, mean weight gain in supplemented sub-group of group B was significantly higher compared to group A (p>0.05) and non-supplemented sub-group of group B (p<0.05).Conclusions: Significant number of SAM children remain anemic when treated with current guidelines. Additional vitamin B12 supplementation in vitamin B12 deficient group showed improvement in weight gain among SAM children.
Impact of COVID-19 pandemic on diabetes: a cross-sectional study at urban health centre in Goa
Authors: Gauns Sneha Laxman , Dhupdale Nitin Y.
Published: January 2022

Background: Diabetes is an important comorbidity which is contributing to the mortality among COVID-19 patients. There are limited studies in Goa which have measured the impact of COVID-19 on the diabetes. Therefore, this study is undertaken to measure the impact of lockdown on glycaemic control in patients with T2DM. The study objectives were to assess the changes in HbA1c and to identify some factors affecting the glycaemic control during the pandemic on the urban population of Goa during the period of pandemic. Methods: A cross-sectional comparative study was undertaken during August to September 2020 amongst Diabetic patients undergoing treatment at Santa Cruz (Goa). Data was collected via oral questionnaire and from patients records at 6 months before and after lockdown after IEC approval. The data was entered into excel v2010, and analysed using SPSS v22 and expressed as simple proportion and percentages.Results: Out of total 50 patients enrolled in the study, the mean post-lockdown HbA1c (8.2±2.1) was found to be higher as compared to pre-lockdown values (7.3±1.3) and the difference was statistically significant (p<0.05). The Chi Square test was calculated comparing HbA1c after lockdown with Diet, exercise and drug compliance which was found to be statistically significant (p<0.05).Conclusions: Mean HbA1c of 50 T2DM patients was higher post lockdown. There is a need to re enforce necessary lifestyle modification and prescribed drug compliance for adequate diabetes control during COVID-19 pandemic to reduce overall morbidity.
A study of demographic and economic profile of COVID-19 mortalities in tertiary health care hospital setting
Authors: Kulshrestha Alok , Gupta Girjesh , Gumashta Raghavendra , Mahor Rajendra Singh , Kulshrestha Manu
Published: January 2022

Background: The health care system could not cope up with upsurge of cases being reported. This enormous magnitude of patient load derailed functionality of hospitals and has put in public health challenges to prevent subsequent pandemics and ensure all time readiness of health care system. This study focused to understand the interactive phenomenon among demographic and economic profile of COVID-19 mortalities in a hospital setting of a tertiary health care facility.Methods: A cross sectional study was undertaken using retrospective data analysis and qualitative study through group discussions among clinical subject specialist of various streams to assess and arrive at a reasoned cause analysis targeted towards prospective technical gains for institutional, individual and facility-based strengthening.Results: The age group 31-70 years had highest COVID-19 deaths (80%) with 51-70 years representing very high deaths (46.9%). Least mortalities were noted among those with occupation of agriculture (7.1%). Zone wise distribution shows that the joint family of east zone showed highest percentage of COVID-19 mortalities among females (22.2%) whereas it was lower among males (10.1%) however in the same zone and in the type of family.Conclusions: The study concludes of felt need for elaborate preparedness of programmatic, managerial and implementer-based facility support to enable health care facility for minimizing and preferably zeroing mortalities due to ongoing or future pandemics. It shall surely provide the quantum and directionality to the needed efforts by all stakeholders at various levels of interventions for sustainable gains directed towards universal health care.
Experience and adaptability of menstrual cup as a menstrual hygiene management method among its users in Kerala
Authors: C. Sreedevi , A. K. Jayasree , Zachariah Shilu Mariam , N. Divyamol , K. S. Deepak
Published: January 2022

Background: Inadequate menstrual management has long been a major health issue. A growing number of women are turning to menstrual cups as a viable and secure choice. Because it is not an absorbent like tampons, the risk of infection and other severe health problems is rare or absent. Current study is conducted to assess the perceived benefits and difficulties faced by those who use menstrual cup as a method of menstrual hygiene management (MHM) technique.Methods: A cross sectional study was undertaken among 211 women who had used menstrual cup for at least six consecutive cycles. Participants were selected using snowball sampling and data was collected by an online questionnaire.Results: Mean age of participants was 32.16 years and majority got information regarding cup from friends or online sources. Experience of insertion and removal became significantly easier after the third time use onwards. Majority of the health problems and economic difficulty for purchasing MHM products significantly got reduced after starting the use of cup. Few reported allergy and irritation 6 (3%), rashes 2 (1%), dryness 5 (2.5%) and infection 4 (2%). Difficulty in availability of clean water 15 (7.2%), access to clean toilet 3 (1.4%), need for privacy 8 (3.8%) and difficulty in sterilization while travelling 44 (21.2%) were other reported challenges. Improvement in attendance 78 (38.4%), work participation 115 (55.8%), economic benefit 190 (91.3%), health benefits 143 (70.4%) and social activity158 (76.7%) were reported by participants after starting cup use.Conclusions: Menstrual cup is a safe and comfortable alternative. Health concerns are significantly less compared to other MHM products. More awareness campaigns and better availability of cup should be there in the community.
Being autistic during the COVID-19 process: from a public health nurse’s perspective
Authors: Yildirim Nilufer , Elmas Semra
Published: January 2022

Parents have an important role in supporting, controlling and managing autistic children's daily life at home. During the COVID-19 pandemic, routine life has changed and a decision for social isolation has been made. The purpose of this case study is to provide an overview of how the child with autism performs daily activities during the pandemic process, the state of self-care skills, and what are the daily developer activities at home. Data collection methods used in this study are interviews and observations. The results of this study show that children with autism can be supported, supervised and guided effectively by their parents at home. It is thought that the case report will provide an idea for diagnosis, and create a training and consultancy program for public health nurses working with autistic children in the field.
Noise pollution and post-COVID-19 pandemic mobility: a case for ambient noise
Authors: Kumar Mohan , Naik Gitismita
Published: January 2022

Noise as a hindrance to health is a low priority in India. The existing statutory controls for noise pollution in India are highly inadequate amidst an implementation gap and should better suit Indian culture and social set-up. Though ubiquitous in nature, community noise and industrial noise are the two major settings from where noise occurs. Exposure to noise above the threshold and over prolonged periods can lead to auditory and non-auditory effects on health; including but not limited to cardiovascular diseases, neurosis, mental illness, stomach ulcers, respiratory disorder exacerbations, sleep disturbances, fetal and maternal complications, child developmental disabilities, psychological dysfunctions/ negative social behavior, road traffic and industrial accidents. The social and economic costs associated with noise pollution are manifold. COVID-19 pandemic has forced countries worldwide to enforce lockdowns resulting in an involuntary ambient noise reduction and other ecological changes like cleaner rivers and air. To sustain the environmental ‘gains’ of enforced lockdowns, it is important for national governments and international health agencies to emphasize better implementation of rules governing pollution in addition to adopting/adapting newer proven technologies; making ‎post-COVID-19 pandemic mobility more environmentally sound, healthy ‎and sustainable. Noise pollution mitigation strategies should be worked out at city levels and having a coordinated and long-term integrated noise pollution research is the need of the hour.
Effect of Different Organic Sources on Nutrient Dynamics and Microbial Count of Black Gram [Vigna mungo (L.) Hepper]
Authors: Kumar N. Vinod , Patil M.B. , Nadadouda B.T. , Beerge Ramesh
Published: January 2022

Background: Concerning fertilization, the pulse crops are more responsive to organic manures but indiscriminate and continuous use of chemical fertilizers has venomous effects on physical, chemical and biological properties of the soil thereby affecting the sustainability of crop production, besides causing environmental pollution. Methods: The study aimed at understanding the effect of different organic amendments on nutrient dynamics of black gram (Vigna mungo), which was carried out at the IFS unit, College of Agriculture, Vijayapur, during Kharif-2019 to study the effect of different combinations of organic sources on nutrient availability, nutrient uptake and soil microbial load in black gram. Result: The application of vermicompost + ghanajeevamrutha @ 100% RDP + Rhizobium + PSB recorded significantly higher soil organic carbon (SOC) (0.70%), soil available nitrogen (291.39 kg ha-1), phosphorus (36.30 kg ha-1) and potassium (580.53 kg ha-1) and significantly higher uptake of nutrients i.e., nitrogen (52.07 and 75.43 kg ha-1), phosphorus (10.12 and 16.08 kg ha-1) and potassium (37.67 and 55.42 kg ha-1) at 45 and 75 DAS compared to all other treatments. Similarly, application of FYM + vermicompost @ 100% RDP + Rhizobium + PSB has recorded the highest microbial count of bacteria [24.40 × 106 CFU (Colony Forming Units) g-1], fungi (17.0 × 103 CFU g-1) and actinomycetes (7.50 × 103 CFU g-1), demonstrating the importance of usage of organics for improving the nutrient availability, uptake and microbial load in black gram.
Backstepping-based state estimation for a class of stochastic nonlinear systems
Authors: Yin Xin , Zhang Qichun
Published: January 2022

The state estimation problem is investigated for a class of continuous-time stochastic nonlinear systems, where a novel filter design method is proposed based on backstepping design and stochastic differential equation. In particular, the structure of the filter is developed following the nonlinear system model, and then the estimation error dynamics can be described by a stochastic differential equation. Motivated by backstepping procedure, the nonlinear dynamics can be converted to an Ornstein–Uhlenbeck process via the control loop design. Thus, the estimation can be achieved once the estimation error is bounded and the variance of the error can be optimized. Since the ideal estimation error is a Brownian motion, the filter parameters can be selected following the Lyapunov stability theory and variance assignment method. Following the same framework, the multivariate stochastic systems can be handled with the block backstepping design. To validate the presented design approach, a numerical example is given as the simulation results to demonstrate the state estimation performance.
The WNT/β-catenin pathway regulates expression of the genes involved in cell cycle progression and mitochondrial oxidative phosphorylation in the postmitotic cardiac myocytes
Authors: Olcum Melis , Cheedipudi Sirisha M. , Rouhi Leila , Fan Siyang , Jeong Hyun-Hwan , Zhao Zhongming , Gurha Priyatansh , Marian Ali J.
Published: January 2022

Introduction: Aging is associated with cardiac myocyte loss, sarcopenia, and cardiac dysfunction. Adult cardiac myocytes are postmitotic cells with an insufficient proliferative capacity to compensate for myocyte loss. The canonical WNT (cWNT) pathway is involved in the regulation of cell cycle reentry in various cell types. The effects of the cWNT pathway on the expression of genes involved in cell cycle reentry in the postmitotic cardiac myocytes are unknown. Aim: The aim of the study was to identify genes whose expression is regulated by the β-catenin, the indispensable component to the cWNT signaling, in the postmitotic myocytes. Methods and Results: Cardiac myocyte-specific tamoxifen-inducible MerCreMer (Myh6-Mcm) mice were used to delete the floxed exon 3 or exons 8 to 13 of the Ctnnb1 gene to induce gain-of-function (GoF) or loss-of-function (LoF) the β-catenin, respectively. Deletion of exon 3 leads to the expression of a stable β-catenin. In contrast, deletion of exons 8-13 leads to the expression of transcriptionally inactive truncated β-catenin, which is typically degraded. GoF or LoF of the β-catenin was verified by reverse transcription-polymerase chain reaction (RT-PCR), immunoblotting, and immunofluorescence. Myocyte transcripts were analyzed by RNA-Sequencing (RNA-Seq) at 4 weeks of age. The GoF of β-catenin was associated with differential expression of ~1700 genes, whereas its LoF altered expression of ~400 genes. The differentially expressed genes in the GoF myocytes were enriched in pathways regulating the cell cycle, including karyokinesis and cytokinesis, whereas the LoF was associated with increased expression of genes involved in mitochondrial oxidative phosphorylation. These findings were validated by RT-PCR in independent samples. Short-term GoF nor LoF of β-catenin did not affect the number of cardiac myocytes, cardiac function, myocardial fibrosis, myocardial apoptosis, or adipogenesis at 4 weeks of age. Conclusion: Activation of the β-catenin of the cWNT pathway in postmitotic myocytes leads to cell cycle reentry and expression of genes involved in cytokinesis without leading to an increase in the number of myocytes. In contrast, suppression of the β-catenin modestly increases the expression of genes involved in oxidative phosphorylation. The findings provide insights into the role of β-catenin of the cWNT pathway in the regulation of cell cycle reentry and oxidative phosphorylation in the postmitotic cardiac myocytes.
Life Alterations and Stress During the COVID-19 Pandemic in Japan: Two-Time Comparison
Authors: Okuyama Junko , Seto Shuji , Fukuda Yu , Ito Kiyoshi , Imamura Fumihiko , Funakoshi Shunichi , Izumi Shin-Ichi ,   Department of Physical Medicine and Rehabilitation, Tohoku University Graduate School of Medicine  2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan,   Core Research Cluster of Disaster Science, Tohoku University, Miyagi, Japan,   International Research Institute of Disaster Science (IRIDeS), Tohoku University, Miyagi, Japan,   Faculty of Letters, Notre Dame Seishin University, Okayama, Japan,   Miyagi Psychiatric Center, Miyagi, Japan
Published: January 2022

No other infectious disease that has had a long-lasting impact on humanity in recent times has caused as much hardship as the coronavirus disease, COVID-19. While several cross-sectional surveys have reported the effects of the pandemic on daily life, there have been very few longitudinal reports from Japan. Therefore, we conducted web-based questionnaire surveys 131 and 610 days after the first case of COVID-19 infection was reported in Japan. There were 244 and 220 participants in the first and second surveys, respectively. The percentage of participants who felt stressed increased from 76 to 97% from the first to the second survey, while the frequency of going out and playing sports/exercising did not change. Regarding the problems faced due to COVID-19, the number of people who mentioned the word “stress” increased significantly in the second survey. The changes in perceived stress under difficult circumstances over a period of time can aid prediction and support during the COVID-19 pandemic in the future.
Population Density and Regional Differences Determine the Probability of COVID-19 Infection
Authors: Karaki Hideaki ,   Foundation of Food Safety and Security Central Building, 1-23-6 Hamamatsu-cho, Minato-ku, Tokyo 105-0013, Japan
Published: January 2022

With the passage of almost two years since the outbreak of COVID-19, the characteristics of the infection have become clearer. It is now known that the peaks of infections recur approximately every four months, the probability of infection varies greatly by region, and the probability of infection correlates with population density.
COVID-19 and Spanish Flu, the Representative Pandemics of the 21st and 20th Centuries
Authors: Shinoda Sumio ,   Collaborative Research Center for Infectious Diseases in India, Okayama University Tsushima-naka, Okayama, Okayama 700-8530, Japan
Published: January 2022

We are still in the early stage of 21st century and the two pandemics Spanish flu and COVID-19 are the presentative pandemics in 20th and 21st centuries, respectively. The Spanish flu pandemic raged from 1918 to 1920, just after World War I. It was the first influenza pandemic worldwide; since then, humankind has experienced many such pandemics. Spanish flu is caused by a virus. However, since virology was not well established at that time, the new clinical system was needed to cope with “unknown pathogen”; during the pandemic, high infection rates were recorded, but our predecessors managed to somehow tackle the situation. With respect to the ongoing COVID-19 pandemic, both the virus and its genome were clarified quickly. Nonetheless, it has turned out to be quite an intriguing infectious disease, with the high rates in developed countries, such as the US and those in Europe, which have aging societies, and low rates in developing countries such as those in Africa, where the population is largely young. Here, I compared and discuss the two pandemics, COVID-19 and Spanish flu.
Agent-Based Simulation and Modeling of COVID-19 Pandemic: A Bibliometric Analysis
Authors: Tang Jing , Vinayavekhin Sukrit , Weeramongkolkul Manapat , Suksanon Chanakan , Pattarapremcharoen Kantapat , Thiwathittayanuphap Sasinat , Leelawat Natt ,   International School of Engineering, Faculty of Engineering, Chulalongkorn University 254 Phayathai Road, Pathumwan, Bangkok 10330, Thailand,   Disaster and Risk Management Information Systems Research Unit, Chulalongkorn University, Bangkok, Thailand,   Thammasat Business School, Thammasat University, Bangkok, Thailand,   Department of Industrial Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand
Published: January 2022

The coronavirus disease has caused an ongoing pandemic worldwide since 2019. To slow the rapid spread of the virus, many countries have adopted lockdown measures. To scientifically determine the most appropriate measures and policies, agent-based simulation and modeling techniques have been employed. It can be challenging for researchers to select the appropriate tools and techniques as well as the input and output parameters. This study conducted a bibliometric analysis, especially a co-word network analysis, to classify relevant research articles into five clusters: conceptual, economic-based, organizational, policy-based, and statistical modeling. It then explained each approach and point of concern. Through this, researchers and modelers can identify the optimal approaches for their agent-based models.
Author Addendum Conundrum: Reconciling Author Use of Addenda With Publisher Acceptance
Authors: Byl Lauren
Published: January 2022

The purpose of this paper is simultaneously to investigate researcher use and awareness of author addenda (e.g., the Scholarly Publishing and Academic Resources Coalition [SPARC] author addendum) and publisher awareness and acceptance of the same. Researchers at U15 Group of Canadian Research Universities institutions were targeted, and a survey was sent to faculty, graduate, and postdoctoral associations to share with their members. Following a low response rate, the survey was sent to a listserv of copyright librarians in Canada with a message that encouraged them to share it with researchers at their institutions. Eighty-one researchers responded to the survey. Eighty-six percent of researchers (n = 70) indicated that they were unaware of author addenda. Researchers were asked to identify how often they negotiate their publishing agreements, and of those who answered the question, 84.2% (n = 64) responded that they never negotiate. Thirteen publishers or publishing organizations were contacted and asked if they would participate in phone interviews about copyright practices and author addenda. Two large multinational publishers agreed to participate. Both publishers indicated that very few authors attempt to negotiate their agreements and that of those who choose to negotiate, even fewer use addenda. Both indicated that they do not accept the SPARC author addendum. This study’s small sample sizes mean that more information needs to be collected before firm conclusions can be drawn. Based on the responses from the two large publishers, the best way to help Tri-Agency-funded researchers may be for libraries and the Tri-Agency to negotiate with publishers for funder-based exceptions.
Transforming Your Conference Presentation into a Journal Article
Authors: MacDonald Katya
Published: January 2022

In many disciplines, most conference presentations end when the conference does; they do not go on to become peer-reviewed articles. Yet there is also research to suggest that continuing to work with a conference paper to turn it into an article leads to higher research productivity overall, with additional benefits of increasing a researcher's confidence, motivation, and capacity for further research (Lee & Boud, 2003).This article was itself once a conference presentation or, more precisely, a workshop entitled “Transforming Your Conference Paper into a Journal Article” developed for University of Saskatchewan and Saskatchewan Library Association member librarians, and presented to researchers and writers from diverse disciplines. At those presentations attendees asked whether I would be turning this presentation into an article – a very meta question that did indeed seem like a logical next step! Synthesizing multidisciplinary scholarship on academic writing, resources from academic writing coaches, and case studies, this piece is intended to be a DIY workshop focusing on concrete strategies for addressing major barriers in the conference paper-to-article editing process.
Mentoring Library School Interns at a Distance: Insights Gained from a Remote Community of Practice
Authors: Hemming Deborah , Phinney Jackie
Published: January 2022

In Fall 2020, while working remotely due to the COVID-19 pandemic, we initiated a Community of Practice (CoP) model for library school interns working on a video tutorials accessibility project for Dalhousie University Libraries. This feature outlines the background of the project, our approach to training interns remotely on Camtasia software, the development of the CoP, and our key takeaways as supervisors. While the CoP was originally intended as a source of support for the group of interns, the experience ended up being incredibly beneficial to us in our development as supervisors as we learned to mentor at a distance. We reflect on how our mentorship styles changed throughout the project and explore future directions for continuing the project with a new cohort of library interns.
ESTIMATION OF THE FOSSIL FUEL FRACTION COMPONENTS DUE TO THE SUESS EFFECT IN URBAN AREA
Authors:   Department of Physics, University Cheikh Anta Diop, Dakar, Senegal., Sene Matar , Ndeye Maurice ,   Radiocarbon Laboratory, Institut Fondamentale dAfrique Noire (IFAN), University Cheikh Anta Diop, Dakar, Senegal., Diouf Abdou ,   Department of Physics, Atoms Lasers Laboratory, University Cheikh Anta Diop, Dakar, Senegal.
Published: January 2022

Long used in the domain of archaeology, the C14 isotope has become an essential tracer in the evaluation of environmental fossil pollution. Since modern times, the combustion of fossil fuels such as coal, oil, natural gas, etc. in urban and/or industrialized areas releases a significant amount of fossil CO2 into the environment. Thisincrease the concentration of CO2, but also causes changes in the isotopic composition of carbon resulting in a deceased of the C14 concentration in the atmosphere and in other carbon reservoirs (terrestrial and marine biosphere).This phenomenon is the SUESS effect. The most favorable types of samples for such a study are leaves of trees or cernes. These reflect better the changes of the radiocarbon concentration in the atmosphere due to the biological assimilation of carbon from the air through photosynthesis. The evaluation of the Suess effect in polluted areas (Dakar region:UCAD Botanic Garden, Mbao Forest, SAR Factory, Beach)can be done using mass balance equations. From this model, we determined the fraction of fossil fuels .The values we found vary between 0.25% in UCAD Botanic Garden and 4.19% in Mbao Forest, and they are all positive, which effectively proves the existence of the Suess effect in our sites.
PREVALENCE OF CARPAL TUNNEL SYNDROME SYMPTOMS AMONG DENTISTS IN BENGHAZI CITY - LIBYA
Authors:   BDs, MDPH, Assistant Lecturer At Preventive and Community Dentistry Department, Head of Pedodontic, Orthodontic, and Preventive and Community Dentistry Department At Libyan International Medical University., Ali Abdelnabi Abdelmonem , Mohammed Al Kuwafi Rafeeq ,   BDS, MSc, German Board Of Oral And Maxillofacial Surgery, Doctoral Degree By LBMS, Lecturer at Oral and Maxillofacial Department, Vice Dean at Libyan International Medical University., Abdulsalam Hashim Khadeejah ,   BDS, General Dental Practitioner At Libyan International Medical University., Ahmed Bugedar Marwa ,   BDS, General Dental Practitioner At Libyan International Medical University.
Published: January 2022

Introduction: Many diseases may affect the nerves of a wrist, one of them is Carpal Tunnel Syndrome (CTS). In the general population, the frequency of CTS prevalence ranged between 3% and 6%. Objectives: To demonstrate the prevalence of CTS symptoms among dentists working in Benghazi-Libya. Methods: A cross-sectional study was conducted in 2019. 205 dentists working in 14 different dental clinics across the city were asked to fill in a questionnaire regarding the symptoms of CTS. Results: Out of 205 questionnaires distributed, only 132 dentists (64.4 %) responded, 73 were male (55.3%) and 59 (44.7%) were female. Out of those participants, 81 dentists (61.3 %) had one or more symptoms of CTS. 32 dentists (24.2%) experienced hand or wrist pain at night, whereas 42 dentists (31.8%) complained of wrist pain during the daytime. In addition, 19 dentists (14.4%) felt hand numbness and 34 (25.8%) suffered from hand weakness during work. Moreover, hand-tingling problems were observed in 23 dentists (17.4%), and the difficulty with grasping and using small objects were reported in 19 dentists (14.4%). Finally, the difficulty of handling manual devices and surgical forceps was detected in 12 dentists (9.1%) and 37 dentists (28%) respectively. Conclusion: This study shows a significant number of dentists working in Benghazi have symptoms of Carpal Tunnel Syndrome.
ATYPICALPRESENTATION OF PREECLAMPSIA. ABOUT A CASE
Authors: Atfi F. , Abbassi M. Jalal I. El , Lamrissi A. , Fichtali K. , Bouhya Maternity El Harouchi Casablanca S.
Published: January 2022

3 to 5% of pregnancies are complicated by pre-eclampsia, which remains one of the main causes of fetal-maternal mortality and morbidity worldwide. The rate is higher in Morocco where the lack of prenatal consultation explains why pre-eclampsia is diagnosed at advanced stages. It is also responsible for 10 to 15% of maternal deaths in the Western world, and it remains the second leading cause of maternal death in France after the hemorrhage during delivery. Severe early pre-eclampsia (before 32 weeks of pregnancy) is associated with a risk of maternal mortality 20 times higher than after 37 weeks, and a higher risk of perinatal complications: prematurity, intrauterine growth retardation, premature detachment of the normoinsere placenta and perinatal mortality [3].Its pathophysiology is complex and multifactorial. The identification of biochemical and biophysical markers that point to placental and endothelial dysfunction allows us to improve our practices through new screening tests (4), which make it possible to target at-risk pregnancies, and to initiate treatment early. Currently, the coexistence of arterial hypertension, proteinuria and edema is arbitrary and inconstant. Preeclampsia can occurwithout the clinical data mentioned above or appear before the second half of pregnancy. Its symptoms are variable and reflect multisystem dysfunction [3]. Its development is unpredictable and can be overwhelming. The objective of this article is to report a case of atypical preeclampsia (before week 20 of gestation) associated with a HELLP Syndrome then to analyze the clinical features of atypical forms, differential diagnosis and progress in biochemical markers and biophysics that can aid in diagnosis.
IDIOPATHIC THROMBOCYTOPENIC PURPURA(ITP) AND ROLE OF A UNANI DRUG IN ITS MANAGEMENT. A SINGLE CASE STUDY
Authors:   P.G.Scholars, Deptt. of Moalijat(Medicine)., Zahoor Ahmad Shiekh , Afzal Asma ,   P.G.Scholars, Deptt. of Moalijat(Medicine)., Ul-Islam Naquib- ,   Professor, Deptt. of Moalijat (Medicine) Regional Research Institute of Unani Medicine, NaseemBagh Campus, University of Kashmir, Srinagar J&K (INDIA) 190006.
Published: January 2022

Idiopathic Thrombocytopenic Purpura (ITP) is immune- mediated with involvement of autoantibodies, most often directed against the platelet membrane glycoprotein IIb/IIIa, which sensitise the platlet, resulting in premature removal from the circulation by cells of the reticulo-endothelial system.ITP is a blood disorder that causes a decrease in the number of platelets in the blood. Platelets help stop bleeding. So, a decrease in platelets can result in easy bruising, bleeding gums, and bleeding inside the body. The lower the platelet count, the greater the risk of bleeding. ITP may be acute or chronic. Eventhough, most cases of ITP are self-limiting, but treatment include steroids, other drugs and in resistant cases, splenectomy is the treatment option. Even though classical Unani texts has no mention of any such disease, but this disease can be discussed under the title of bleeding disorders.A single Unani drug was selected in a dosage of 500 mgs twice daily in a patient who was otherwise advised splenectomy for the disease.
CLASSIFICATION OF BAOULE SENTENCES ACCORDING TO FREQUENCY AND SEGMENTATION OF TERMS VIA CONVOLUTIONAL NEURAL NETWORKS
Authors:   Ecole Superieure Africaine Des Technologies dInformation Et De La Communication (ESATIC), Cote dIvoire., Kouassi Konan Hyacinthe , Adles Kouassi Francis ,   Ecole Superieure Africaine Des Technologies dInformation Et De La Communication (ESATIC), Cote dIvoire., L. Diety Guy ,   Universite Virtuellede Cote dIvoire (UVCI)., Asseu Olivier ,   Ecole Superieure Africaine Des Technologies dInformation Et De La Communication (ESATIC), Cote dIvoire.,   Institut National Polytechnique Felix Houphouet Boigny (INP-HB), Cote dIvoire.
Published: January 2022

In the Baoule language, several sentences express the same fact. Classification of sentences is a task of Natural Language Processing (NLP). Deep learning has turned out to be a kind of method that has a significant effect in this area. In this paper, we propose a convolutional neural network (CNN) based system for sentence classification. We introduce into this system a word representation model to capture semantic characteristics by encoding the frequency of terms and segmenting the sentence into clauses. The experimental results show that our system produces satisfactory results.
ACUTE ADRENAL INSUFFICIENCY AFTER CORTICOSTEROID THERAPY TO GAIN WEIGHT CASE REPORT
Authors:   Endocrinology Department CHU Agadir Morocco., Damoune I. ,   Laboratoire de la recherche en science de la sante Faculty of Medicine University Ibn Zohr Agadir Morocco., Akioud F. ,   Endocrinology Department CHU Agadir Morocco., Loubna L ,   Endocrinology Department CHU Agadir Morocco., Ajdi F. ,   Endocrinology Department CHU Agadir Morocco.,   Laboratoire de la recherche en science de la sante Faculty of Medicine University Ibn Zohr Agadir Morocco.
Published: January 2022

Obesity is considered a sign of beauty in some regions, especially in southern Morocco and some sub-Saharan countries, the use of glucocorticoids to gain weight is a common practice among women in these regions. We report the case of a female patient who presented with acute adrenal insufficiency after long term exogenous administration of steroids to gain weight.
RISK FACTORS AND CLINICAL PROFILE OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
Authors:   Consultant Cardiology, SSH, GMC Jammu, Jammu and Kashmir, India., Ali Nasir , Ahmed Wani Owais ,   DrNB Cardiology, SSH, GMC Jammu, Jammu and Kashmir, India., Maqbool Syed ,   Consultant Cardiology, SSH, GMC Jammu, Jammu and Kashmir, India., Masood Khan Suhail ,   DrNB Urology, SSH, GMC Jammu, Jammu and Kashmir, India., Mohi Ud Din Dar Parvez ,   Assistant Professor And Head of Trauma and Emergency Medicine, All India Institute of Medical Sciences, Vijaypur, Jammu, Jammu and Kashmir, India.
Published: January 2022

Background: New instances of AMI reveal the presence of risk factors in the population that contribute to a rise in AMI. The occurrence of recurring AMI attacks, on the other hand, indicates the quality of care received by the patient during the AMI attack and subsequent treatment. The goal was to look into the risk factors and clinical profiles of those who had an acute myocardial infarction. Methods: The current hospital-based cross-sectional study lasted two years and involved 50 eligible participants who were chosen based on the inclusion and exclusion criteria established for the purpose of determining the clinical profile and risk variables. Results:The most typical age range was 61-70 years (36 percent ). The average age of the study groups patients was 53.88 years. The study group was dominated by male patients. This male-to-female ratio does not necessarily reflect the prevalence of myocardial infarction in the population. In the current study group, the most prevalent MI was inferior wall MI (46 percent ). 18 patients (36%) were smokers, and 20 patients (40%) of the 50 patients had problems. Thirteen of the patients developed arrhythmias (26 percent ). Conclusions:The elderly were the most typically impacted. Males were more likely to have AMI. In the current investigation, the most common lesion was inferior wall myocardial infarction. Smoking was the most common risk factor discovered in this investigation.
FAST DISINTEGRATING TABLETS - A NEW ERA IN NOVEL DRUG DELIVERY SYSTEM
Authors:   Department of Pharmaceutics, Matoshri College of Pharmacy, Eklahare, Nashik (Maharashtra)., Pawar Harshala , Pawar Aishwarya ,   Department of Pharmaceutics, Matoshri College of Pharmacy, Eklahare, Nashik (Maharashtra)., N. Bhavsar Shraddha ,   Department of Pharmaceutics, Matoshri College of Pharmacy, Eklahare, Nashik (Maharashtra).
Published: January 2022

Among all dosage forms, fast-Disintegrating tablets are one of the most commonly used dosage forms, especially in children, because their nervous system and muscular system are not well developed compared to them in adults. and in adult patients with Parkinsons disease or hand tremors. Some fixed dosage forms, such as capsules and tablets, now have difficulty swallowing (dysphagia), which results in many cases of non-compliance and renders therapy ineffective. The most preferred routes of administration for various drugs are oral dosage forms and the oral route with specific limitations such as first-pass metabolism by the liver, psychiatric patients, at-risk patients, and non-cooperators. FDTs dissolve easily in saliva without the need for water. Fast- Disintegrating tablets dissolve in saliva in a minimum of less than 60 seconds., And these are really fast-digesting tablets. FDT formulations contain super disintegrants to increase the rate of tablet degradation in the buccal cavity. FDTs have advantages because they are easy to manufacture, have the right dosage, good chemical and physical strength, and are an ideal alternative for children and adult patients. FDTs have a faster rate of degradation, faster absorption, so that in vitro drug release time increases and this property of the drug (dosage form) increases bioavailability. FDT formulations have specific advantages in both conventional tablet and liquid dosage forms. There are many technologies for spray drying, cotton candy process, sublimation, melt granulation, direct freeze pressing / lyophilization, phase transition process, mass extrusion, etc. This overview provides brief information on FDT, including the definition, benefits, needs or requirements of FDT, key characteristics FDT, limitations, various challenges in the development of FDT, marketed tablet formulations that cause rapid digestion and so on.
ORGANIZATIONAL PERFORMANCE CHALLENGED BY THE EVALUATION
Authors:   Maitre-Assistant en Sociologie du Travail et des Organisations, Enseignant Chercheur au Departement de Sociologie-Anthropologie de la Faculte des Sciences Humaines et Sociales de lUniversite dAbomey-Calavi (Benin)., B. Kouin Jaures
Published: January 2022

Assessment is a management tool for organizational performance. Indeed, the production of a good performance in a company begins with the evaluation of the working conditions of the employees that make it possible to know if the factors of production are favorable and if the workers are motivated. Then comes the evaluation of the employees performance, which is the mechanism for assessing his productivity through his behavior in the workplace, his adherence to the established culture. Thus, effective management of the organization depends on taking into account the human dimension, which is the source of performance. It is advisable, through this article, to deconstruct the concept of performance in order to configure it in a sociological perspective which considers the organization as structured by the interrelation of the social actors superimposed on different strata where the hierarchical superiors command the subordinates to generate models of social production and reproduction. This article examines organizational performance through the lens of the sociology of organizations through the human dimension interface. It is the result of a survey carried out in a public agency and at the ministry in charge of secondary education and has the general objective of analyzing the performance of employees based on their behavior in the workplace. It is qualitative in nature and models of self-determination and interactionism have been referenced for analysis of the data.
PSEUDOTUMOR CEREBRI COMPLICATING MULTISYSTEM INFLAMMATORY SYNDROME IN CHILD
Authors:   Service De Pediatrie, Hopital Cheikh Khalifa Ibn Zaid, Casablanca., Almiaadi Hasnaa , Ech-Charii Nadia ,   Service De Pediatrie, Hopital Cheikh Khalifa Ibn Zaid, Casablanca., Chekhlabi Nabila ,   Service De Pediatrie, Hopital Cheikh Khalifa Ibn Zaid, Casablanca., Dini Nouzha ,   Service De Pediatrie, Hopital Cheikh Khalifa Ibn Zaid, Casablanca.
Published: January 2022

Purpose :To report a case of pseudotumor cerebri in a Child associated with coronavirus disease. Methods : A previously 12 year old boy presented to our hospital with a 5 days history of fever,headache,vomiting and general malaise.Initial laboratory investigation revealed significantly elevated neutrophilic leukocytosis and markers of inflammation were significantly elevated, pharyngeal swab for severe acute respiratory syndrome coronavirus (SARS-CoV 2) by polymerase chain reaction was negative , while anti-sars-CoV-2 antibody was highly reactive.Neuro-ophtalmic examination revealed a visual accuity of 20/20 in both eyes with bilateral papilloedema.Neurogical examination was otherwise normal,MRI of the brain and magnetic resonnance venogram revealed abnormalities consistent with increased intracranial pressure.The opnening pressure of cerebrospinal fluid was 40 cmH2O and CSF composition was normal. Results : Based on our patients symptom the diagnostic of pseudotumor cerebri associated with multisystem inflammatory syndrome in child was made and the child was traited with oral acetazolamide.Edema of the optic disc regressed following therapy Conclusion : In conclusion pseudotumor cerebri syndrome may be seen in the content of SARS-CoV-2 infection and should be kept in the differential diagnosis for headache and vision loss in this population. Clinicians need to be aware of this potential neuro-ophtalmic complication in MIS-c diagnosis and treatment can prevent visual loss.
Occurrence and antibiotic resistance of Vibrio parahaemolyticus isolated from the Tunisian coastal seawater
Authors: Zaafrane Sami , Maatouk Kaouthar , Alibi Sana , Ben Mansour Hedi
Published: January 2022

Vibrio parahaemolyticus is a gram-negative bacterium ubiquitous in seawater or estuarine water throughout the world. It is a major cause of seafood gastroenteritis complications. In this study, the presence of V. parahaemolyticus was investigated in 66 seawater samples collected during 2018 from 15 stations spread along the Tunisian coast using selective media including CHROMagar Vibrio media. The results show that only eight samples contained V. parahaemolyticus. However, while Vibrio alginolyticus was detected in all samples; both Vibrio cholerae and Vibrio vulnificus were not found. Nine of the presumed V. parahaemolyticus colonies were purified on tryptic soy agar from eight positive samples then identified by the API 20E biochemical test and confirmed by the presence of a specific target toxR gene. The detection of virulence genes, thermostable direct haemolysin (tdh) and thermostable-related haemolysin (trh), by the polymerase chain reaction (PCR) showed the presence of only two trh-positive isolates. The assessment of antibiotic susceptibility of the V. parahaemolyticus isolated revealed a complete resistance to colistin, amikacin, penicillin and cefotaxime and a total sensitivity to chloramphenicol, nitrofurantoin and sulfamethoxazole-trimethoprim with a multiple antibiotic resistance index (MAR) ranging from 0.4 to 0.5.
Heavy metal pollution in selected upland tributaries of Sri Lanka: comprehension towards the localization of sources of pollution
Authors: Kodikara K. A. S. , Lewandowski S. , De Silva P. M. C. S. , Gunarathna S. D. , Madarasinghe S. K. , Ranasinghe P. , Jayatissa L. P. , Dahdouh-Guebas F.
Published: January 2022

This study aimed to assess the heavy metal (HM) profile of the main upland tributaries of three major rivers, the Mahaweli, the Deduru and the Gin Rivers, which are commonly used for urban water supply in Sri Lanka. The HM profiles of arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg) were investigated by ICP-MS. Land-use classification was performed to locate the main sources of pollution. Mean pH, TDS and conductivity showed significant inter-site mean differences (p < 0.001). The mean contents of the HMs, considering all rivers, were observed in the order [Hg] > [As] > [Pb] > [Cd] at the sources and [As] > [Hg] > [Pb] > [Cd] at the river mouths. Particularly, in the Mahaweli River, the mean As content was 0.08 ± 0.05 μg·L−1 and showed an increasing trend from the source to the river mouth. In the Deduru River, the mean Hg content was 0.14 ± 0.15 μg·L−1, and of all rivers studied, the highest content of 0.50 ± 0.17 μg·L−1 was recorded. The Gin River showed significant inter-site mean differences (p < 0.05) in [Pb], [As] and [Hg]. In all rivers studied, [As] was significantly higher in water samples collected near agricultural lands and urban areas as compared with the other land-use/cover types, which was further proved by a significant positive correlation (coefficient = 0.479, p = 0.0325). We, therefore, emphasized that HM pollution is more likely due to anthropogenic activities in the upper catchment with less lithogenic contamination. However, national water quality management should be further strengthened and new policy enforcement is emphasized.
3D numerical simulation of dam-break flow over different obstacles in a dry bed
Authors: Maghsoodi Reza , Khademalrasoul Abdolghafour , Sarkardeh Hamed
Published: January 2022

In this research, a numerical investigation was carried out on the effect of obstacle presence on the water flow during the dam-break in a dry bed. The validity of the numerical simulations was confirmed after comparing the results with the experimental evidence. Rectangular, trapezoidal and triangle obstacles were simulated numerically to explain the obstacle effect on the water flow. Water surface tracking and turbulent flow were modeled using the Volume of Fluid (VOF) method and the standard k-ω model, respectively. Pressure and velocity variations during the dam-break flow are presented and analyzed.
Spatial distribution, geochemical behaviors and risk assessment of antimony in rivers around the antimony mine of Xikuangshan, Hunan Province, China
Authors: Sheng Linlin , Hao Chunming , Guan Shengdi , Huang Zhanbin
Published: January 2022

Pollutants derived from antimony (Sb) mining can easily cause pollution of surrounding water bodies. However, qualitative source analysis of river pollution is mostly conducted, and quantitative source analysis is still lacking. A total of 21 water samples were collected to analyze the pollution status of the heavy metal element Sb, explore the Xikuangshan (XKS) area river heavy metals pollution mechanism, undertake quantitative analysis of the sources of pollution, and carry out irrigation water suitability assessment and potential ecological risk assessment. The results showed that, compared with the mining non-affected area, the maximum excess multiple of Sb in surface water and rivers in Hunan XKS area is 411.31. When the river fluid flows through the mining-affected area, the heavy metal element Sb content increases rapidly, and then decreases due to dilution process. Positive matrix factorization (PMF) source analysis showed that the main source of Sb pollution in the rivers is the impact of mining and smelting (83.60%), followed by the role of waste rock leaching (16.40%). After irrigation, 27.78% of the river water had strong ecological risks, and 16.67% had extremely strong ecological risks. This achievement provides a theoretical basis and technical guarantee for protecting and using the local water body of the mining area.