bluuebunny/crossref_metadata_2025 huggingface dataset:
Mixup (Sample Pairing) Can Improve the Performance of Deep Segmentation Networks
Authors: Isaksson Lars J. , Summers Paul , Raimondi Sara , Gandini Sara , Bhalerao Abhir , Marvaso Giulia , Petralia Giuseppe , Pepa Matteo , Jereczek-Fossa Barbara A.
Published: October 2021

Researchers address the generalization problem of deep image processing networks mainly through extensive use of data augmentation techniques such as random flips, rotations, and deformations. A data augmentation technique called mixup, which constructs virtual training samples from convex combinations of inputs, was recently proposed for deep classification networks. The algorithm contributed to increased performance on classification in a variety of datasets, but so far has not been evaluated for image segmentation tasks. In this paper, we tested whether the mixup algorithm can improve the generalization performance of deep segmentation networks for medical image data. We trained a standard U-net architecture to segment the prostate in 100 T2-weighted 3D magnetic resonance images from prostate cancer patients, and compared the results with and without mixup in terms of Dice similarity coefficient and mean surface distance from a reference segmentation made by an experienced radiologist. Our results suggest that mixup offers a statistically significant boost in performance compared to non-mixup training, leading to up to 1.9% increase in Dice and a 10.9% decrease in surface distance. The mixup algorithm may thus offer an important aid for medical image segmentation applications, which are typically limited by severe data scarcity.
A New Hand-Movement-Based Authentication Method Using Feature Importance Selection with the Hotelling’s Statistic
Authors: Doroz Rafal , Wrobel Krzysztof , Porwik Piotr , Orczyk Tomasz
Published: October 2021

The growing amount of collected and processed data means that there is a need to control access to these resources. Very often, this type of control is carried out on the basis of bio-metric analysis. The article proposes a new user authentication method based on a spatial analysis of the movement of the finger’s position. This movement creates a sequence of data that is registered by a motion recording device. The presented approach combines spatial analysis of the position of all fingers at the time. The proposed method is able to use the specific, often different movements of fingers of each user. The experimental results confirm the effectiveness of the method in biometric applications. In this paper, we also introduce an effective method of feature selection, based on the Hotelling T2 statistic. This approach allows selecting the best distinctive features of each object from a set of all objects in the database. It is possible thanks to the appropriate preparation of the input data.
Evaluating Dropout Placements in Bayesian Regression Resnet
Authors: Shi Lei , Copot Cosmin , Vanlanduit Steve
Published: October 2021

Deep Neural Networks (DNNs) have shown great success in many fields. Various network architectures have been developed for different applications. Regardless of the complexities of the networks, DNNs do not provide model uncertainty. Bayesian Neural Networks (BNNs), on the other hand, is able to make probabilistic inference. Among various types of BNNs, Dropout as a Bayesian Approximation converts a Neural Network (NN) to a BNN by adding a dropout layer after each weight layer in the NN. This technique provides a simple transformation from a NN to a BNN. However, for DNNs, adding a dropout layer to each weight layer would lead to a strong regularization due to the deep architecture. Previous researches [1, 2, 3] have shown that adding a dropout layer after each weight layer in a DNN is unnecessary. However, how to place dropout layers in a ResNet for regression tasks are less explored. In this work, we perform an empirical study on how different dropout placements would affect the performance of a Bayesian DNN. We use a regression model modified from ResNet as the DNN and place the dropout layers at different places in the regression ResNet. Our experimental results show that it is not necessary to add a dropout layer after every weight layer in the Regression ResNet to let it be able to make Bayesian Inference. Placing Dropout layers between the stacked blocks i.e. Dense+Identity+Identity blocks has the best performance in Predictive Interval Coverage Probability (PICP). Placing a dropout layer after each stacked block has the best performance in Root Mean Square Error (RMSE).
Damage Detection of the Rod in the Crossflow Using Surrogate-Based Modelling
Authors: Upnere S. , Auzins J.
Published: October 2021

An effective and accurate methodology is developed to create an inverse surrogate model for the mass reduction analysis of the rod in the rod bundle inserted in the crossflow. The performance of two surrogate modelling approaches has been evaluated. These models are the Response Surface Method and Legendre polynomial approximations. The relationship between dominant frequencies, support stiffness and rod mass derived from Computational Fluid Dynamics simulations is used as input data for approximations. The selection of sample points is implemented with a new type of orthogonal design. The results have shown that the proposed methodology can reliably replace the finite volume model and drastically reduce computational time.
Private and Public Sector Employer Actions for Home Office Workers During the COVID-19 Epidemic
Authors: Nowacki Krzysztof , Grabowska Sandra , Lis Teresa
Published: October 2021

A research was conducted among the employees referred to work in the home office in connection with the announced state of the epidemic in Poland. The research was conducted using a questionnaire method, the study was attended by 199 respondents. The research is burdened with an error in the selection of statistical sample units, which resulted from the respondents’ involvement and their truthfulness. The aim of the article is to assess the activities of employers from the private and state sectors in Poland, related to the delegation of employees to work in the home office, and to analyze the skills and possibilities of self-organization of work by employees. An important result of the survey was to demonstrate the differences in the behavior of public and private sector employers. The study shows that the private sector has adapted better to sudden changes than the state sector.
Regional brands produced beyond the region: An analysis of beer brands from recently closed breweries in Europe
Authors: Hasman Jiří , Hána David , Materna Kryštof
Published: October 2021

Global industry has been undergoing changes in the concentration of brand ownership and production, with acquisitions and closures being a major factor in this evolution. The impacts of such activities are commonly studied from an economic perspective and from the perspective of internal firm-level and deal-level factors, while the influence of external geographical factors is largely neglected. Our research focuses mainly on the importance of geographical cultural factors affecting beer brands whose production location was moved after the closure of the original breweries. The research includes a complete sample of 30 brands from recently closed breweries across Europe. Brands are divided into seven categories according to how their marketing strategy has (or has not) changed in terms of exploiting regional and national identity. The overall success of these brands is then measured in terms of the development of their share in the home countries’ markets. Differences in brands’ strategies and successes are explained through a wide range of country-level factors and the individual characteristics of the breweries. It is shown that the level of beer tradition or identity in the countries, as well as the country’s beer life-cycle position, plays a crucial role in the evolution of the studied brands.
Indigenous journalism, media innovation, and social change: A review of previous research and call for more critical approaches
Authors: Ní Bhroin Niamh , Sand Stine , Rasmussen Torkel
Published: October 2021

Indigenous journalism can facilitate the inclusion of Indigenous voices in the public sphere, thereby contributing to social change. Contemporary Indigenous journalism is in part facilitated by the introduction and diffusion of paradigmatic media innovations, including the Internet, mobile technology, and social media. Based on a literature review, we investigate how media innovations are understood to facilitate Indigenous journalism and find that few empirical studies directly address this question. Analyses of Indigenous journalism, reaching beyond the potential for increased access to media and for amplification of Indigenous voice, are lacking. Furthermore, little research investigates how the appropriation of new technological affordances influence the production of Indigenous journalism. Our review also indicates that while Indigenous political participation can be facilitated by media innovation, these innovations can also serve to reinforce existing power relations. We submit that more critical analytical approaches are required to investigate how media innovations might facilitate the potential of Indigenous journalism for social change.
Sliding Mode Control of Hybrid Renewable Energy System Operating in Grid Connected and Stand-Alone Mode
Authors: Benadli Ridha , Bjaoui Marwen , Khiari Brahim , Sellami Anis
Published: October 2021

This paper studies innovative application of sliding mode control (SMC) for a Hybrid Renewable Energy System (HRES) in grid-connected and autonomous modes of operation. The considered HRES includes a photovoltaic (PV), wind turbine (WT) based on a Permanent Magnet Synchronous Generator (PMSG). The PV generator is coupled to the common DC bus via a DC/DC converter. The latter is controlled by an MPPT algorithm based on the Adaptive Perturbation and Observation Algorithm Method (APOAM) to search the optimum working of this source. A SMC is utilized to manage the PV voltage to achieve the Maximum Power Point (MPP) by altering the obligation duty cycle. The battery interfaced by a bidirectional buck-boost DC/DC converter can be charged or discharged depending on the production situation. On the one hand, the wind turbine conversion chain is equipped with a PMSG and a rectifier controlled to regulate the operating point of the wind turbine to its optimum value. During a Stand-Alone Mode (SAM) operation, the Voltage Source Converter (VSC) was used for controlling the output voltage in terms of amplitude and frequency delivered to the AC load. However, in Grid-Connected Mode (GCM) operation, the VSC was adapted to control the electrical parameters of the grid. To better appreciate the advantages of the proposed SMC approach, we have proposed a series of comparative tests with the conventional PI control in the operating modes GC and SA and under different scenarios. The proposed control strategy has undeniable advantages in terms of control performance and very low total harmonic distortion THD value compared with the conventional PI control. Finally, It is concluded that the proposed approach improves the quality and provides a stable operation of the HRES.
Target motion management in breast cancer radiation therapy
Authors: Piruzan Elham , Vosoughi Naser , Mahdavi Seied Rabi , Khalafi Leila , Mahani Hojjat
Published: October 2021

Background

Over the last two decades, breast cancer remains the main cause of cancer deaths in women. To treat this type of cancer, radiation therapy (RT) has proved to be efficient. RT for breast cancer is, however, challenged by intrafractional motion caused by respiration. The problem is more severe for the left-sided breast cancer due to the proximity to the heart as an organ-at-risk. While particle therapy results in superior dose characteristics than conventional RT, due to the physics of particle interactions in the body, particle therapy is more sensitive to target motion.

Conclusions

This review highlights current and emerging strategies for the management of intrafractional target motion in breast cancer treatment with an emphasis on particle therapy, as a modern RT technique. There are major challenges associated with transferring real-time motion monitoring technologies from photon to particles beams. Surface imaging would be the dominant imaging modality for real-time intrafractional motion monitoring for breast cancer. The magnetic resonance imaging (MRI) guidance and ultra high dose rate (FLASH)-RT seem to be state-of-the-art approaches to deal with 4D RT for breast cancer.
Towards Green and Smart Seaports: Renewable Energy and Automation Technologies for Bulk Cargo Loading Operations
Authors: Philipp Robert , Prause Gunnar , Olaniyi Eunice O. , Lemke Florian
Published: October 2021

In 2018, 4.1 billion tonnes of freight and 437 million passengers passed through the 1200 European ports. This dimension of geographically concentrated activities is the rationale that ports are characterised by a high-energy demand and a high share of emissions. Driven by a growing awareness for a cleaner environment, a stronger focus on sustainability and intensified environmental regulations, ports are forced to take responsibility when it comes to environmental issues. As a response, in recent studies, the concept of ‘green ports’ emerged. Simultaneously, in the context of digitalisation, the term ‘smart ports’ has received growing attention in the latest scientific discussions, too. Since an important driver towards greener maritime operations is linked to digitalisation, we argue that digital efforts in ports should next to the automation of inherent logistics processes also contribute to reducing the emissions and energy demands. Previous studies have primarily concentrated on the automation of container handling operations. Hence, there exists a research gap concerning the automation of bulk cargo handling operations in ports. Thus, this study addresses the question of how to automate the dry bulk cargo loading operations in the frame of a green and smart port development. The developed case study refers to the seaport of Wismar, whereby the results show that the digitalisation and greener port operations can be successfully aligned. Overall, this study extends the discussion on green and smart port development, while it contributes to the scientific literature by proving that both conceptual ideas can be achieved in the operating business.
Numerical Study on Erosion Wear and Strength of Main Gas Pipelines Bends
Authors: Yaroslav Doroshenko , Galyna Kogut , Yuliia Doroshenko , Oleh Tarayevs’kyy , Taras Pyrig
Published: October 2021

The purpose of this work is to ensuring the strength of main gas pipelines bends by studying the peculiarities of single-phase and multiphase flows movement through the internal cavity, the processes of erosion wear and the wall stress state. The problem of synergistic influence of gas-dynamic processes (uneven pressure distribution in the internal cavity), temperature difference and erosion wear on the stress state of the bends of main gas pipelines was solved by numerical simulation. Based on the results of simulation the processes of bends erosion wear, an algorithm for three-dimensional simulation of bend walls erosion defects was developed. The complex three-dimensional geometric shape of the erosion defects of the bend wall varied according to the rate of erosion wear process. This algorithm made it possible to determine the regularities for the influence of the bend erosion defects magnitude on bends stress state. It was established that considering the maximum depth of bend erosion defects 9.6 mm, 10.5 mm and 11.9 mm, the equivalent stresses in the deepest places of the erosion defect were greater than on the concave side of the bend and in straight sections of the pipeline.
Financial Stability dan Misstatement Laporan Keuangan dengan Opportunity Fraud sebagai Variabel Moderating
Authors: Suryawan Kadek Yoga , Budiasih I Gusti Ayu Nyoman
Published: October 2021

The research aims to obtain empirical evidence of the influence of Financial Stability on Misstatement of Financial Statements and to determine the ability of Opportunity Fraud to moderate the influence of Financial Stability on Misstatement of Financial Statements. This research was conducted at the Indonesia Stock Exchange (IDX) which has corporate financial data, especially manufacturing companies. The method of determining the sample using a purposive sampling technique. The number of samples in this study were 308 observational data. The analysis technique used is Moderated Regression Analysis (MRA). The results showed that Financial stability had a positive effect on the misstatement of financial statements of manufacturing companies listed on the Indonesia Stock Exchange in 2015-2018 and Opportunity Fraud weakened the influence of Financial Stability on the Misstatement of Financial Statements of manufacturing companies listed on the Indonesia Stock Exchange in 2015 - 2018.

Keywords: Experience; Competence; Independence; Audit Fees; Quality Audits.
Alokasi Belanja Rutin dan Belanja Modal pada Indeks Pembangunan Manusia Tahun Anggaran 2015-2017
Authors: Kakadir Petrus , Suaryana I Gusti Ngurah Agung , Putri I Gusti Ayu Made Asri Dwija , Wirawati Ni Gusti Putu
Published: October 2021

This study aims to determine the effect of routine and capital expenditure allocations on the human development index in the regency/municipality of Papua province. This study covers 29 districts/cities in the province of Papua using an associative quantitative approach. The analysis technique used is multiple linear regression analysis technique. The results of the analysis show that routine expenditures have a positive and significant effect on the human development index, while capital expenditures have a negative and non-significant effect on the human development index. The failure of capital expenditures to affect the human development index occurred, in addition to the low amount of capital expenditure allocated in an effort to improve people's welfare, also due to the allocation of capital expenditures that had not been carried out on target.

Keywords: Routine Shopping; Capital Expenditures; Human Development Index.
Reaksi Pasar Atas Pengumuman Anugerah Program Penilaian Peringkat Kinerja Perusahaan dalam Pengelolaan Lingkungan Hidup
Authors: Wirajaya I Gde Ary , Pangestu Teresia Arta
Published: October 2021

This study aims to examine the market's reaction to information regarding the announcement of a company performance rating assessment program award in environmental management. Market reaction is measured by abnormal return around the announcement date of the environmental management program. This research is conducted at the Indonesia Stock Exchange. The population in this study are all publicly listed companies receiving PROPER awards listed on the IDX in 2018 for a total of 51 companies. Samples that met the purposive sampling criteria are 50 companies. The analysis technique used is one sample t-test and independent samples t-test.  The results of this study indicate that there is a market reaction around the PROPER rating announcement date, and there is no different market reaction between companies with good ratings and companies with bad ratings.

Keywords: Event Study; Abnormal Return; PROPER.
Kompetensi Akuntansi Sumber Daya Manusia dan Kinerja Pegawai dengan Produktivitas sebagai Variabel Intervening
Authors: Arsani Ni Kadek Budi , Rasmini Ni Ketut
Published: October 2021

This study aims to determine the effect of human resource accounting competence on employee performance with BUM Desa productivity as an intervening variable. Data collection was done through a questionnaire. This study uses a quantitative approach with primary data sources and secondary data. The population in this study were all BUM Desa in Gianyar Regency. The sample in this research is BUM Desa in Gianyar Regency with purposive sampling method. The analysis technique used is path analysis. The test results show that human resource accounting competence has a positive effect on the productivity of BUM Desa in Gianyar Regency. The productivity of BUM Desa has a positive effect on employee performance at BUM Desa, Gianyar Regency. Human resource accounting competence has a positive effect on employee performance at BUM Desa Gianyar Regency. Human resource accounting competence has a positive effect on employee performance through productivity at BUM Desa, Gianyar Regency.

Keywords: Human Resource Accounting Competence; Productivity; Employee Performance.
Pengujian Monday Effect pada Indeks LQ-45 di Bursa Efek Indonesia pada saat Pandemi
Authors: Kepakisan Komang Bagus Surya , Damayanthi I Gst Ayu Eka
Published: October 2021

Research in Indonesia found many anomalies in the stock market, such as the Phenomenon of Monday effect. The diversity of research results encourages to re-research the Phenomenon of Monday effect on different conditions, namely pandemic. The purpose of this study is to find out the occurrence of Monday effect on the Indonesia Stock Exchange at the time of the pandemic. This research was conducted on all LQ-45 companies in March to October 2020. Data collection by observing the available secondary data. The analysis technique used is one sample t-test. This research proves that there is no difference in average return on Monday which the phenomenon of Monday effect doesn’t occur during a pandemic.

Keywords: Monday Effect; LQ-45 Index; Indonesia Stock Exchange.
TRANSFORMACIJA ULICE CVIKAUER U KEMNICU, NEMAČKA: PARTICIPATIVNO DELOVANJE KAO OSNOV PROJEKTANTSKOG REŠENJA
Authors: Priljeva Sofija
Published: October 2021

Značaj ljudskog delovanja i socijalnih interakcija u formiranju određenih prostora, sagledani su i interpretirani kroz primer participacije građana u procesu urbanog planiranja u gradu Kemnicu (nem. Chemnitz) u Nemačkoj. Dovodeći u vezu postojeće stanje jednog istočnonemačkog grada i želju njegovih stanovnika, posetilaca i gradske vlasti da stvore klimu u kojoj prostor komunicira sa ljudima, koji se oblikuje i razvija na osnovu ljudske inicijative, a zauzvrat pruža mir i prijatno mesto za odrastanje i život, postavlja se pitanje koji su to uslovi koje treba ispuniti da bi se uspostavio ovakav sklad, i da li se uvođenjem participacije građana izražava njihovo osnovno pravo - pravo na grad.
IMPLEMENTACIJA PAMETNOG SISTEMA U PROJEKAT STAMBENE JEDINICE ZA SLEPU OSOBU
Authors: Sejdija Renata
Published: October 2021

Ovaj rad se bavi istraživanjem i analizom problema i ograničenja, sa kojima se susreću osobe bez čula vida, kao i posledicama gubitka vida. Istraživanje treba da doprinese svest o poboljšanju kvaliteta života osobama sa invaliditetom. Upravo je to i cilj projekta, koji je postignut tako što se pametna tehnologija uvela u stambenu jedinicu. Na taj način, stvorio se jedan nezavisan život, jer je i osnovna funkcija ovog stambenog prostora da poveća stepen slobode.
РЕВИТАЛИЗАЦИЈА РУРАЛНОГ НАСЕЉА ГОДИЊЕ – ЗАСЕЛАК ЛЕКОВИЋИ
Authors: Бајовић Никола
Published: October 2021

Рурална насеља у Црној Горизаузимају значајан дио територије, као таквипредстављају значајан сегмент у очувањуидентитета културе, а имају и битну улогу уразвојном потенцијалу државе.Циљ рада је да се системским истраживањем,дедуктивном методом, анализом различитихставова, детерминише типологија, свеобухватнапроблематика руралних насеља и понуди јединственорјешење у будућем развоју. Тема овог рада је наједном мјесту приказати и препознати, ограничења,могућности, могући правац ревитализације и обновеједног типичног руралног насеља Црмничке регије,насеља Годиња и оживјети га новим савременимоблицима привређивања.Након спроведене анализе изнијете су икомпаративне предности руралних насеља, такопосебну пажњу у њиховом даљем развоју требаобратити на: очување квалитета природногпејзажа, унапређења квалитета туристичке понуде,активирање и ревитализацију пољопривреде иактивирање непосредног планинског залеђа у сврхутуристичког развоја. Неспорно је да руралнипростори Црне Горе имају потенцијала да прерасту уразвијене средине уз адекване стратегије одрживогруралног развоја што би свакако утицало нацјелокупни развој Црне Горе.
IDEJNO REŠENJE VINARIJE NA FRUŠKOJ GORI
Authors: Sailović Anđela
Published: October 2021

U radu se predstavlja projekat kompleksa vinarije sa svim funkcionalnim, pratećim cjelinama. Osnovni cilj rada je bilo istražiti postojeće vinarije, te ih analizirati i zatim pozitivne vrijednosti implementirati u radu. Za ispunjavanje ovog cilja bilo je potrebno odabrati određene kriterijume kojima se treba voditi.
KROZ OBJEKTIV: ARHITEKTURA, GRAD I FOTOGRAFSKI MEDIJ U XX I XXI VEKU
Authors: Aničić Sanja
Published: October 2021

Osnovni predmet istraživanja jeste arhitektonska fotografija u XX i XXI veku, prikazana kroz interdisciplinarni obuhvat. U prvom delu rada prikazana je istorija arhitektonske fotografije kojom se obuhvata njen uticaj na razvoj modernog pokreta, kao i uticaj na modernog čoveka i promenu njegove percepcije o prostoru. Drugi deo rada se posvećuje razmatranju uloge fotografskog medija u arhitekturi modernizma, kao i njegov uticaj na savremeni grad i društvo.
BEZBJEDNOST INFORMACIONIH SISTEMA
Authors: Šmitran Dejna , Morača Slobodan
Published: October 2021

Ovaj rad u sebi objedinjuje nekoliko krucijalnih aspekata računarskih mreža, počevši od organizacije i administracije virtuelne privatne mreže, do zaštite sistema i bezbednosti podataka. Organizacija mreže se bavi hardverskim i softverskim rješenjima koja su potrebna da bi se mreža realizovala po zahtijevima korisnika. Administraciju mreže čine njeno održavanje, nadgledanje i unapređivanje kako bi ona bila dugotrajna i efikasna, te na taj način zadovoljavala najviše IT standarde. Zaštitu sistema i bezbednost podataka čine sva hardverska i softverska rješenja neophodna da spriječe i otklone potencijalne prijetnje po sigurnost i bezbjednost sistema.
UTICAJ NEMATERIJALNE MOTIVACIJE NA STEPEN ZADOVOLJSTVA ZAPOSLENIH
Authors: Kulizić Jovana
Published: October 2021

U radu je prikazan uticaj nemateri­jalne motivacije na stepen zadovoljstva zaposlenih, na osnovu kojih se predlažu mere unapređenja.
UTICAJ LIDERSTVA NA ORGANIZACIONO UČENJE
Authors: Galečić Slavica
Published: October 2021

U radu se analizira uticaj liderstva na organizaciju koja uči, na osnovu kojih se predlažu mere unapređenja.
MARKETING DOGAĐAJA U IT INDUSTRIJI
Authors: Voćkić Jelena
Published: October 2021

Razvoj informacionih tehnologija uticao je na to da dođe do bržeg i rapidnijeg razvoja svih delatnosti, a naročito onih koje su srodne. Marketing događaja se danas, baš zbog postojanja informacionih tehnologija, u mnogome razlikuje od nonoga koje je bilo karakteristično za prošli vek. Tradicionalni postulati marketinga su i dalje prisutni, ali u izmenjenom i dopunjenom obliku. Adekvatnom upotrebom svih medija, tradicionalnih i savremenih, može da se poveća vidljivost i promocija nekog događaja, a kada je u pitanju događaj u sferi informacionih tehnologija, ciljna grupa je ta kojoj se sama promocija mora prilagoditi i približiti na adekvatan način.
UNAPREĐENJE PROCESA SKLADIŠTENJA U ORGANIZACIJI „VRTLARI“ DOO MALI IĐOŠ
Authors: Brkljač Biljana
Published: October 2021

Predmet rada jeste prikaz procesa skladištenja u organizaciji „Vrtlari“ DOO iz Malog Iđoša. Nakon teorijskih osnova iz oblasti logistike, kompletnog procesa skladištenja, kao i metoda i tehnika koje su korišćene u radu detaljno je predstavljen i analiziran proces vođenja skladišnog poslovanja ove organizacije. U završnici rada za uočene probleme definisane su adekvatne mere unapređenja.
ЗНАЧАЈ И УЛОГА ТЕХНИЧКОГ ЗАКОНОДАВСТВА ЗА БЕЗБЕДНОСТ ПРОИЗВОДА НА ТРЖИШТУ
Authors: Вујичић Драгана
Published: October 2021

У раду су дата основна објаш­њења везана за појам техничког законодавства, са посебним освртом на техничко законодавство ЕУ. Детаљно су објашњени Нови и Глобални приступ. Анализирана је инфраструктура квалитета и ниво техничког законодавства у Републици Србији.
GAP АНАЛИЗА ЗА ИМПЛЕМЕНТАЦИЈУ СТАНДАРДА ISO 45001 НA ПРИМЕРУ КОМПАНИЈЕ „COFICAB SERBIA DOO DEČ“
Authors: Глумац Вања , Хаџистевић Миодраг
Published: October 2021

У овом раду приказан је развој стандардизације, као и стандарда из области безбедности и здравља на раду. Објашњени су захтеви стандарда Међународне организације за стандардизацију – ISO 45001. Стандард дефинише захтеве које треба да испуни систем менаџмента безбедношћу и здрављем на раду. Затим је урађена анализа испуњености ових захтева у компанији COFICAB SERBIA DOO. При томе је коришћена GAP анализа, приказане су неусаглашености са стандардом и предложене мере за њихово отклањање.
ANALIZA BEZBEDNOSTI OD POŽARA HOTELA
Authors: Jevtić Paja
Published: October 2021

U radu je data analiza propisa I problema požarne bezbednosti u hotelima. Sprovedena je komparativna analiza propisa iz oblasti zaštite od požara za hotele u Republici Srbiji i Republici Hrvatskoj, zak­ljučeno je da su hrvatski propisi zahtevniji od srpskih. Na osnovu aktuelnih propisa u Srbiji, urađena je analiza bezbednosti od požara hotela „Stari Krovovi“ i utvrđeno je da je rizik od požara na prihvatljivom nivou. Vreme evakuacije dobijeno proračunskom, kao i softverskom metodom, je u granicama dozvoljenim propisima.
Value of Ultrasound in Evaluation of Abnormal Axillary Lymph Node
Authors: Hussien Abdelmohsen Radwan , El-Quadi Monaliza , Oconnell Avice
Published: October 2021

Understanding of the various appearances of axillary lymph nodes (LNs) is essential for diagnosing and planning of breast cancer treatment. In this article, the role of ultrasound in detecting abnormal appearing metastatic LNs s is discussed, with emphasis on most of the ultrasonographic features and tools which might help improve detection of axillary LN pathology.
Effects of keratinocyte-derived and fibroblast-derived exosomes on human epidermal melanocytes
Authors: Shi Hai-Xia , Zhang Ru-Zhi , Xiao Li , Wang Li
Published: October 2021

Background:

Exosomes have been demonstrated to carry proteins, membrane lipids, mRNAs and microRNAs which can be transferred to surrounding cells and regulate the functions of those recipient cells.

Objectives:

The objective of the study was to investigate the effects of exosomes released by keratinocytes and fibroblasts on the proliferation, tyrosinase activity and melanogenesis of melanocytes.

Methods:

Melanocytes, keratinocytes and fibroblasts obtained from human foreskin were cultured and exosomes secreted by keratinocytes and fibroblasts were harvested from the culture supernatants by ultracentrifugation. Each exosome fraction was divided into two parts; one part was subjected to high-throughput sequencing using an Illumina HiSeq sequencer to characterize the microRNA expression profiles, while the other part was labeled with the fluorescent dye PKH67 and was then co-cultivated with epidermal melanocytes.

Results:

High-throughput sequencing analysis showed 168 differentially expressed microRNA within exosomes derived from keratinocytes and from fibroblasts, 97 of those being up-regulated with the other 71 down-regulated. Gene ontology analysis showed that the target genes responsible for these differentially expressed microRNAs were mainly enriched in the protein-binding region of molecular functions. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis showed that target genes regulated by differentially expressed microRNA were mainly involved in mitogen-activated protein kinase (MAPK) signaling pathway, Ras signaling pathway, cAMP signaling pathway and Wnt signaling pathway. Keratinocyte-derived exosomes were taken up by melanocytes co-cultured with them and promoted the proliferation, tyrosinase activity and melanin synthesis of those melanocytes. However, fibroblast-derived exosomes had no similar effects on melanocytes.

Conclusion:

Keratinocyte-derived exosomes but not fibroblast-derived exosomes were taken up by melanocytes in co-culture and significantly stimulated their proliferation, tyrosinase activity and melanin synthesis. Those different effects may be mainly due to the differential expression of microRNAs in exosomes derived from the different types of cells.

Limitations:

Electron microscopy of the obtained exosomes and in-depth study of apparently differentially expressed microRNAs were not performed.
Pulmonary arterial hypertension: achievements and realities of modern treatment, a look into the future
Authors: Martynyuk Tamila V. , Chazova Irina E.
Published: October 2021

The paper summarizes the most important aspects of modern treatment of patients with pulmonary arterial hypertension (PAH): the goals of therapy are indicated, the issues of risk stratification of PAH progression/mortality, the place of combination specific therapy and switching strategies are considered, as well as new promising approaches to therapy; features of the course of the new coronavirus infection COVID-19 in this category of patients are discussed.
History and perspectives of the defibrillation
Authors: Isaev Georgy O. , Vasin Andrey А. , Mironova Olga Iu.
Published: October 2021

History of the discovery of fibrillation and defibrillation, stages of the development of the concept of defibrillation are described in the article. The differences in mechanisms of different types of defibrillation are given here. The modern state of defibrillation and future trends are discussed in our article.
Dynamics of Holter electrocardiogram monitoring in patients with chronic heart failure and atrial fibrillation on the background of cardiac contractility modulation
Authors: Safiullina Alfiya A. , Uskach Tatiana M. , Sharapova Yulduz S. , Kochetov Anatolii G. , Sapelnikov Oleg V. , Tereshchenko Sergey N.
Published: October 2021

Aim. To evaluate the dynamics of cardiac arrhythmias on the background of cardiac contractility modulation (MCC) in patients with chronic heart failure (CHF) and various forms of atrial fibrillation (AF) on the basis of daily electrocardiogram (ECG) monitoring.
Materials and methods. In 100 patients with CHF and AF, the following studies were performed before implantation of the MCC device and after 12 months of follow-up: 12-channel ECG with an estimate of the width of the QRS complex, transthoracic echocardiography (EchoCG), and Holter ECG monitoring. All patients received long-term optimal drug therapy for CHF before surgery.
Results. The results obtained indicate that there is no effect of MCC on the development and progression of ventricular arrhythmias in patients with CHF and AF during the year of follow-up, both extrasystole and tachyarrhythmias, regardless of the etiology and LVEF (less than 35% or more than 35%), and a decrease in the frequency of AF paroxysms in patients with CHF during treatment. These results are due to the reverse remodeling of the LV myocardium under the influence of the MCC device.
Conclusion. The use of MСС in patients with CHF and AF is a safe method of therapy that does not induce cardiac arrhythmias, including ventricular extrasystole. Large-scale comparative studies are required to evaluate these results.
COVID-19 and features of cardiovascular involvement
Authors: Tsyganova Elena V. , Glukhoedova Nataliia V. , Zhilenkova Aleksandra S. , Fedoseeva Tatiana I. , Iushchuk Elena N. , Smetneva Natalia S.
Published: October 2021

The article provides an overview of current information on the pathogenesis of COVID-19 and organ-specific lesions developing in this disease. The data on inflammation and its biochemical markers, on the features of coagulopathy, endothelial damage and microthrombosis are presented in detail. Particular attention is paid to the role of receptors for angiotensin converting enzyme type 2 and transmembrane serine protease type 2 in the development of organ-specific lesions in COVID-19. The pathogenesis of damage to the cardiovascular system is considered in detail with the presentation of data from foreign literature on changes in the myocardium and the author's results of transthoracic echocardiographic examination in patients who have undergone COVID-19.
Characteristics of patients with chronic thromboembolic pulmonary hypertension according to the Russian National Registry
Authors: Valieva Zarina S. , Martynyuk Tamila V. , Nakonechnikov Sergei N. , Chazova Irina E.
Published: October 2021

Aim. To assess demographic and clinical characteristics, to describe of the functional and hemodynamic status, profile of concomitant pathology, data of instrumental examination in chronic thromboembolic pulmonary hypertension (CTEPH) patients; to study the features of specific and supportive therapy according to the data of the Russian national registry.
Materials and methods. From 2012 till 2020 a multicenter, prospective study in 15 regional expert centers of the Russian Federation (www.medibase.pro) included 404 newly diagnosed CTEPH patients over the age of 18 years in the Russian registry of patients with pulmonary arterial hypertension and CTEPH (NCT03707561). The diagnosis was established by European and Russian clinical guidelines for the diagnosis and management of pulmonary hypertension. 154 inoperable CTEPH patients an additional analysis of specific and supportive therapy was performed.
Results. The study included 404 patients (55.6% women and 44.3% men) at the age of 58.6 [48.6; 69.3] years. Median time from symptom onset to the diagnosis verification waswas 2.4 years (from 0.1 to 2.9 years). 79.1% of patients were in the III and IV functional class (World Health Organization) at the time of diagnosis and in 44.1% with RHF (right heart failure). In assessing the profile of concomitant pathology, it was noted that CTEPH patients were more often with arterial hypertension (39.1%), erosive-ulcerative lesions of the stomach/duodenum (16.1%), atrial fibrillation (13.8%), obesity (13.1%). Distance in 6MWD (6-min walk distance) was 337.2 [250; 422] m, Borg dyspnea index scale 4.1 [3.0; 5.0] points. Hemodynamic parameters according to right heart catheterization were: Mean PAP (pulmonary arterial pressure) (51.114.04) mmHg, CO (cardiac output) (3.50.98) l/min, CI (cardiac index) (2.00.48) l/min/m2, PVR (2008528) dyns/cm5.
Conclusion. According to the Russian registry, inoperable CTEPH patients had precapillary PH (pulmonary hypertension) with severe functional status, in combination with frequent concomitant pathology (arterial hypertension, erosive-ulcerative lesions of the stomach/duodenum, atrial fibrillation, obesity, right heart failure). 66% of inoperable CTEPH patients received specific drug therapy.
The role of New Zealand endemic lizards in Salmonella transmission in the takahē translocation network
Authors:   , Rose Shanna
Published: October 2021

The dynamics of disease in wildlife populations often involve a complex relationship between physiological, environmental and ecological variables. Defining the pattern of pathogen infection between primary hosts, sympatric species and their environments is crucial in the understanding of potential impacts a pathogen may have on its host species. Very little is known about pathogens of native, New Zealand wildlife. Understanding the role pathogens play in structuring communities is crucial in the conservation of threatened New Zealand wildlife species. Salmonella is an important pathogen of reptiles, birds and mammals, and Salmonellosis has caused significant mortality in wildlife around the world. Recently, Salmonella has been isolated from takahē from a private island in the takahē translocation network. Reptiles have been implicated as asymptomatic carriers and transmitters of Salmonella, and lizards from a private (undisclosed) island have been implicated in the transmission of Salmonella to takahē. To investigate the capacity for lizards to act as a Salmonella reservoir in the takahē translocation network, I examined the distribution, abundance and Salmonella prevalence of lizards within takahē territories on the private island and on Maud Island where takahē also reside. Additionally, I investigated the presence of Salmonella in soil and water samples from takahē territories on the private island, Maud Island and at the Burwood Bush takahē rearing facility. Lizard densities on the private island were estimated to be between 466-6020 lizards/ha, and 118-1528 lizards/ha on Maud Island. Salmonella serovars concurrent with those isolated from takahē were isolated from 2% of lizards, 25% of water and 50% of soil samples on the private island, indicating that lizards and the environment play an important role in transmission and maintenance of Salmonella to takahē. Salmonella was not isolated from lizards or environmental samples on Maud Island or at Burwood Bush, indicating prevalence too low to detect in this study or a Salmonella reservoir unique to the private island. Further investigation of Salmonella sources; serovars and seasonal patterns of Salmonella infection is needed to better inform takahē translocation actions on the private island. Additionally, further examination of Salmonella in lizards and the environment is necessary to assess the risk of Salmonella infection to takahē on Maud Island.
The Impact of Waves and Tidal Currents on the Sediment Transport at the Sea Port
Authors: Truong Dinh Duc , Tri Doan Quang , Don Nguyen Cao
Published: October 2021

Dredged sediments in estuarine and coastal waters can cause sediment transport and water pollutant in marine environment since the sediments are diffused to waterbodies under the influence of wave and flow regimes. As a result, it increases turbidity and enhances sediment deposition at dump sites. In Vietnam, few authors have studied and assessed the environmental impact of dumping and dredged materials to the port areas. This paper combines a coupled spectral wind-wave, hydrodynamic, and sediment transport models in order to study the impact of tide and wave conditions to regional sediment transport patterns at Vung Ang port area in Vietnam. The results for the currents and waves were evaluated and validated using field data. Wind and wave data for the calculated domain are extracted from the WAVEWATCH-III (wave data) and NOAA global climate change models (wind data). The calibration and validation of the MIKE 21/3 showed a high conformity between the observed and simulated data based on the mean absolute error (MAE), the RMSE-observation standard deviation ratio (RSR) and the Percent bias (PBIAS). The MIKE 21/3 sediment transport simulation results showed that the highest suspended sediment concentrations were 2.5-3 g/m3 at the dredging position and the increased concentration along the transport route ranged from 1-1.5 g/m3. The simulation results showed the bed level change of the simulated domain. We found that the suspended sediment diffusion area decreased with the respective depth: Layer 1 (65.5 km2), Layer 2 (45.7 km2), and Layer 3 (37.4 km2). Therefore, the simulation results of the dredged materials activities were significantly affected by the wave and tidal regime on the sediment transport. Doi: 10.28991/cej-2021-03091749 Full Text: PDF
Impact of Length and Percent Dosage of Recycled Steel Fibers on the Mechanical Properties of Concrete
Authors: Gul Akhtar , Alam Bashir , Iqbal Muhammad Junaid , Ahmed Wisal , Shahzada Khan , Javed Muhammad Haris , Khan Ezaz Ali
Published: October 2021

The global rapid increase in waste tyres accumulation, as well as the looming social and environmental concerns, have become major threats in recent times. The use of Recycled Steel Fiber (RSF) extracted from waste tyres in fiber reinforced concrete can be of great profitable engineering applications however the choice of suitable length and volume fractions of RSF is presently the key challenge that requires research exploration. The present experimental work aims at investigating the influence of varying lengths (7.62 and 10.16 cm) and dosages (1, 1.5, 2, 2.5, 3, 3.5, and 4%) of RSF on the various mechanical properties and durability of concrete. Test results revealed that the varying lengths and dosages of RSF significantly affect the mechanical properties of concrete. The improvements in the compressive strength, splitting tensile strength, and Modulus of Rupture (MOR) of RSF reinforced concrete observed were about 26, 70, and 63%, respectively. Moreover, the RSF reinforced concrete showed an increase of about 20 and 15% in the yield load and ultimate load-carrying capacity, respectively. The durability test results showed a greater loss in compressive strength and modulus of elasticity and a smaller loss in concrete mass of SFRC. Based on the experimental findings of this study, the optimum dosages of RSF as 2.5 and 2% for the lengths 7.62 and 10.16 cm lengths, respectively are recommended for production of structural concrete. Doi: 10.28991/cej-2021-03091750 Full Text: PDF
Analysis of Conveyance Losses from Tertiary Irrigation Network
Authors: Syed Naeem Shah Bukhari , Shuqi Zhao , Babar Muhammad Munir , Soothar Rajesh Kumar
Published: October 2021

Irrigation canals are generally made through porous soil formations, since the soil is loose porous media – a huge amount of canal water is lost to conveyance losses. The situation becomes direr when these losses result in non-beneficial losses. The Sindh province of Pakistan has more than 70% saline groundwater, conveyance losses to such areas in the province not only become unusable but also creates water management problems. Perhaps the only cost-effective way to address these losses is canal lining. The present study was conducted in the command area of Belharo distributary, Sindh, Pakistan with an aim to determine the extent of losses from the tertiary irrigated network as these water channels are less considered in the literature with regards of conveyance losses. Using water balance method, conveyance efficiency and conveyance losses at 30% lined and 50 and 75% unlined length of the watercourses was observed. The results revealed that the tertiary irrigation channels face an average of 43% conveyance losses and major proportion of these losses is lost to non-beneficial losses from the study area. The study further suggests 75% lining of watercourses in order to minimize non-beneficial losses. This study also infers that with the use of geo-membrane lining, sizeable amount of fresh water can be saved. Doi: 10.28991/cej-2021-03091756 Full Text: PDF
Study of Pressure Distribution on an Irregular Octagonal Plan Oval-Shape Building Using CFD
Authors: Kumar Arun , Raj Ritu
Published: October 2021

This paper aims to study the wind flow characteristics and to analyze the wind pressure distribution on the surfaces around an irregular octagonal plan shape building model. There is a central open space in plan to provide more surface area around the building for natural ventilation. Plan area of the building is 300 m2(excluding the open space) and height is 50 m. Steady state flow of wind with 5% turbulence (moderate turbulence) under atmospheric boundary layer has been taken in the study. Numerical simulation with standard k-e model using ANSYS (CFX) software has been used for the purpose. Flow characteristics has been studied in terms of flow separation, reattachment of flow, creation of wakes and vortices. The surface pressure generated around the model has been studied in terms of coefficient of pressure. The model is symmetrical about both the axes in plan. Hence, study for different wind angle of attacks from 0° to 90° @ 30° interval has been conducted. The flow characteristics and unusual or critical coefficient of pressure on surfaces of the model observed have been discussed. Doi: 10.28991/cej-2021-03091760 Full Text: PDF