bluuebunny/crossref_metadata_2025 huggingface dataset:
Editorial on “Transperitoneal laparoscopic approach for retroperitoneal tumors in adults”
Authors:   Hospital Británico de Buenos Aires, Quildrian Sergio D.
Published: December 2022

In this issue of Revista Argentina de Cirugía, Minetti et al.1 reported the results obtained in a retrospective series with the transperitoneal laparoscopic resection of retroperitoneal tumors. Although the series is not large, it makes evident the great heterogeneity that exists among primary retroperitoneal tumors. Thus, this definition excludes tumors originating in totally or partially retroperitoneal organs (urinary system, adrenal glands, pancreas, or rectum, among others) and the retroperitoneal extension or recurrence of tumors in other locations (lymphomas, germinal tumors, and gastrointestinal tumors with lymph node recurrence). These tumors originate from the vascular, adipose, lymphatic, muscle or neural tissue of the retroperitoneum. Although conventional surgery has been the preferred approach, the use of laparoscopy in several retroperitoneal tumors is increasing.
Implementation of E-Commerce and Web-Based Company Profile on CV. Andromeda Multi Sarana
Authors: Pohan Sry Dhina , Mubarok Mohammad Hilmi
Published: December 2022

CV.Andromeda Multi Sarana (AMS) is a company engaged in swallow consultants that provides solutions for farmers in conventional and modern cultivation in selling wallet business products. The wide sales area for wallet products proves that AMS is successful in marketing wallet products. At AMS, purchase data and wallet product data are processed manually, making it difficult to process large amounts of data and reporting is not integrated to the AMS leadership. The E-commerce system and company profile on AMS are made web-based using the prototype system development method which is useful in facilitating the process of completing the stages of making the system and according to the wishes of the user. The E-commerce system and company profile on AMS produce an integrated system capable of processing large amounts of data and a website that functions to expand AMS' market share with a company profile that explains the purpose of AMS.
Analysis of Domestic Historiographical Works on the History of Museum Business and the State of Russian Museum Historiography
Authors: Deveykis Marina
Published: December 2022

The purpose of the work is to identify, classify and analyze existing historiographical publications on the history of museum business. The study used general historical principles: objectivity, scientific and historicism, as well as methods of systematization and chronological. One of the significant features marking the latest trends in the Russian museum business can be characterized by the appearance of a significant number of publications devoted to the activities of museums, the history of their funds, collections, individual exhibits. At the same time, Russian museum literature has not received a broad historiographical assessment. Russian museologists drew attention to the incompleteness of the Russian historiography of museum business. This study was carried out for the first time, the result of it is the grouping of the entire set of submitted works according to the problem-thematic principle and conclusions on historical periods are given. According to the pre-revolutionary period, it should be noted that at that time the museum business was a fairly new type of professional activity, not fully formed and institutionalized. The Soviet period is characterized by increased research interest and attention to the problem of museums and the historiography of museum business. But the scientific and theoretical groundwork was still being formed at a slow pace. The democratization of society as a whole and the social sphere, education and culture has led to more extensive research of museum business. It is in the modern period that publishing and research activity is significantly increasing. In conclusion, promising directions for further research within the framework of the topic under consideration are presented.
Pengaruh Teknologi Keuangan Terhadap Preferensi Konsumen Memilih Uang Digital Dalam Transaksi Keuangan
Authors: Dewi Sandra , Febria Gheantisa , Anggraini Rina
Published: December 2022

Tujuan dari penelitian ini adalah untuk Untuk mengetahui pengaruh Financial Technology terhadap preferensi masyarakat memilih E-Money sebagai alternatif untuk mempermudah transaksi keuangan di Kota Bukittinggi. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif. Variabel penelitiannya adalah financial technology (X) sebagai variabel bebas dan preferensi konsumen memilih E-Money (Y) sebagai variabel terikat. Pengambilan sampel dengan teknik purposive sampling dengan jumlah sampel sebanyak 100 responden. Sedangkan teknik analisis data yang digunakan adalah analisis regresi sederhana, uji validitas, uji realibilitas, uji asumsi klasik dan uji hipotesis. Hasil data penelitian diuji menggunakan SPSS IBM 26. Berdasarkan hasil penelitian yang didapat melalui analisis regresi sederhana yaitu Y = 0,755 + 0,55X. Hasil penelitian menunjukkan bahwa financial technology berpengaruh positif dan signifikan terhadap prefrensi konsumen memilih E-Money karena thitung 17,564 > ttabel 1,660 dan signifikansi 0,000 < 0,05 maka H1 diterima. Berdasarkan hasi penelitian diharapkan masyarakat mampu untuk adaptif terhadap perkembangan serba modern yang dipengaruhi oleh revolusi industri 4.0 agar perubahan teknologi dapat mempermudah konsumen bukan sebaliknya, disisi lain dukungan dan sosialisai dari regulator (pemerintah) serta lembaga penyedia e-money juga harus ditingkatkan agar masyarakat tidak merasa diberatkan dengan adanya perubahan pada system yang diterapkan
Mengukur Kinerja Layanan Internet Indihome dari Opini Masyarakat Menggunakan Sentimen Analisis Twitter Dengan Metode Naïve Byes
Authors: Himawan Heribertus , Murtadho Rafif , Ferriswara Dian
Published: December 2022

In 2019, 73.7% of Indonesians said that their purpose for using the internet was to access social media. One of the social media used is Twitter. With many tweets that have been published through Twitter, these tweets can contain user opinions on a particular thing, it can be like an event in the surrounding Indihome. Through Twitter, users can discuss their complaints or satisfaction with the Indihome service. For that reason, a method is needed, namely sentiment analysis to find out whether the data contains negative or positive opinions. The author uses the Naïve Bayes method in conducting sentiment analysis on the opinions or opinions of Indihome service users on Twitter, to know how accurate the Naïve Bayes method is applied to sentiment analysis. After testing using the Naïve Bayes method, the results obtained are 82% accuracy, 78% precision, 84% recall, and 81% f1-score.
Pengaruh Komunikasi Dan Lingkungan Kerja Terhadap Kinerja Karyawan Di PT Stars Internasional Surabaya
Authors: Subardini Subardini , Yuniar Dian Vira Anggraeni , Asnawi Anita
Published: December 2022

Tujuan penelitian ini adalah untuk menguji pengaruh komunikasi dan lingkungan kerja terhadap kinerja karyawan yang dilaksanakan di Kantor PT Stars Internasional, Surabaya. Metode kuantitatif digunakan dalam penelitian dengan teknik pengumpulan data menggunakan kuesioner, wawancara dan observasi. Populasi penelitian adalah seluruh karyawan tetap di kantor PT Stars Internasional Surabaya dengan besar sampel yang diambil sebanyak 33 sampel dan analisis data yang dilakukan menggunakan program SPSS versi 25. Teknik analisis data yang digunakan dalam penelitian ini adalah menggunakan pengujian regresi linier berganda, uji koefisien determinasi dan pengujian hipotesis. Berdasarkan hasil penelitian dan uji hipotesis yang telah dilakukan menujukkan bahwa terdapat pengaruh signifikan dari komunikasi dan lingkungan kerja terhadap kinerja karyawan di PT Stars Internasional, Surabaya secara bersama-sama (simultan) hal ini dapat dilihat dari hasil nilai F hitung lebih besar dari F tabel yaitu 9,791 lebih besar dari 3,3158. Hasil uji hipotesis secara parsial komunikasi terhadap kinerja karyawan menunjukkan berpengaruh signifikan hal ini dilihat dari nilai t hitung lebih besar dari t tabel yaitu 2,763 lebih besar dari 2,0423. Hasil uji hipotesis secara parsial lingkungan kerja terhadap kinerja karyawan menunjukkan berpengaruh signifikan hal ini dilihat dari nilai t hitung lebih besar dari t tabel yaitu 2,103 lebih besar dari 2,0423.Untuk hasil uji hipotesis koefisien determinasi (R square) dalam penelitian ini menunjukkan bahwa variabel komunikasi dan lingkungan kerja memiliki pengaruh sebesar 39,5% terhadap kinerja karyawan.
ECD-IMC: an integrated marketing communications model for selected Philippine higher education institutions
Authors: DAGUMBOY ELOIDA
Published: December 2022

Private higher education institutions (HEIs) in the Philippines have been in turmoil due to three major occurrences: the Enhanced Basic Education Act of 2013, the Universal Access to Quality Tertiary Education Act of 2017, and the Coronavirus Disease. These contributed to the abating tertiary enrolment. One scheme for enduring the ordeal is the application of budgetary cuts. Competing in a scarcer market with financial constraints is an arduous task for marketing. The paper aimed to identify the most effective platform blend among numerous communication platforms employed in the industry by recognising the importance of integrated marketing communications (IMC) and maximising HEIs' return on marketing investments. About 380 students, parents, and administrators from five private HEIs in the National Capital Region offering Senior High School programs participated as survey respondents or interviewees. The paper utilised mixed methods, various statistical tools, and variance analyses. Among the twenty marketing communication platforms, the most efficient (efficiency rating>3.736) are referrals/word-of-mouth marketing, free entrance examination, website, scholarships/discounts, and social media. In contrast, in the lower quartile (efficiency rating<3.262) are billboards, television/radio/print ads, souvenir items, sending direct messages to prospective students, and newspaper articles. To some extent, the HEIs implementation level of the various platforms is aligned with communication platforms' efficiency ratings. Further, the study ascertained differences in the preference and reached ratings according to respondents' profiles. Finally, an Efficient, Coherent, and Dynamic (ECD)-IMC model was crafted to help HEI administrators/marketers improve their enrolment with the least possible costs and to provide reference to future researchers.
Communicating about sustainability on @greenpeaceid
Authors: Sirajuddin  , GS Achmad Daengs , Saragih Megasari Gusandra , Surya Elfitra Desy , Sandoval Marcos R. B.
Published: December 2022

Environmental challenges are critical issues that the entire international community is currently dealing with. The number of incidents of factory waste disposal, climate change, and biodiversity extinction all represent a significant threat to all creatures' survival. As a result, Greenpeace, as an environmental group, continues to work to stop the ongoing natural damage. This study aims to find out the sustainable communication model on the Greenpeace social media site. From January 1, 2022, to February 28, 2022, Krippendorff content analysis via Instagram @greenpeaceid was used. Based on the data analysis that has been carried out, sustainability communication on the Instagram @greenpeaceid social media site for the period January 1, 2022, to February 28, 2022, is more dominant in producing posts that contain the benefits of messages that invite people to care about environmental balance.
Digital tourism branding post-pandemic covid-19 on Twitter: Thailand dan Malaysia case study
Authors: Nita Aribah  , Suswanta
Published: December 2022

This study aims to analyse the function of social media as digital tourism branding carried out by Thailand and Malaysia after the COVID-19 pandemic. This research method uses descriptive qualitative methods with the help of the Nvivo 12 Plus application in processing the data. This study uses data from official Twitter social media accounts in Thailand and Malaysia. The results of this study indicate that the analysis of the Twitter conversations of the two accounts shows that the tweets and retweets of @AmazingThailand and @TourismMalaysia are mostly still focused on accounts from their respective domestic regions. The digital tourism branding, which is analysed using marketing communication theory, shows that Thailand and Malaysia have proactive efforts in planning indicators, creation, integration, and marketing strategies. Overall the digital tourism branding efforts carried out by Thailand and Malaysia are quite optimal.
Visualisation of image restoration for Indonesian public officials during the Covid-19 Pandemic
Authors: Pratiwi Miftha , Andarini , Rindang Senja , Setiyowati Rini , Santoso Anang Dwi
Published: December 2022

Most studies on image restoration concentrate on text analysis of firms and CEOs in the Western context; hence, there is a need to explore similar practices in public organisations or public officials in an Eastern context. This study intends to investigate tactics and methods for repairing the image of public officials in eastern nations, including Indonesia, to fill this void. Visual and thematic analysis was performed on a dataset containing 2,000 Instagram posts from seven public officials in Indonesia. According to our findings, the visual analysis identifies six content kinds, while the thematic analysis identifies ten content types. They constitute image restoration methods, such as compensation, bolstering, corrective action, and shifting the blame, and image recovery strategies, such as reducing offensiveness of event, corrective action, and denial. This study reveals that, contrary to western literature, public authorities in Indonesia tend to employ the method of minimising the offensiveness of an occurrence.
Parents' involvement on teen's movie consumption in the pandemic era
Authors: Indriani Sri Seti , Mohamad Permana Rangga Saptya , Basit Abdul
Published: December 2022

Abstract Watching movies at home through movie applications now has become a trend in this pandemic era. Adolescents who have online learning at home are forced to entertain themselves with indoor activities; spending more time watching movies is one example. As one of the online movie platforms, Netflix has gained 204 million subscribers in January 2021, following Amazon Prime with 150 million subscribers. This situation becomes a concern where adolescents seemingly have more freedom and access to select movies without parents' awareness. Adolescents are given trust in their competence to be conscious, critical, and analyse their content despite their age. This research's objects were to acknowledge how adolescents gain access to online movies despite the television content rating system and their parents' involvement in the adolescents' selection of movies. The research was conducted using a qualitative method with a case study approach. Informants were adolescents in the range of 11-14 years old and some parents. Results showed that most adolescents gained access to movies through online applications, namely Netflix, YouTube, Telegram, and illegal websites. These adolescents gained this information from friends and the TikTok application. Regarding the parents' involvement, most adolescents claimed that their parents did not contribute to their selection of movies, seemingly ignorant, and some parents even did not know what their children watch and do in their bedrooms. However, a few of them stated that their parents contributed to their selection of movies but sometimes gave adolescents some permission to watch unsuitable movies based on the television content rating system.
The value of signs in social media accounts of #kelasblogger Instagram community
Authors: Salman  , Rusadi Udi , Nasrullah Rully
Published: December 2022

The use of communication technology is only limited to a means of exchanging messages. However, there is a significant value behind it. As Baudrillard points out, in a consumer society, people buy products based on sign value, as indicated in this case study. The results of this study indicate that the #Kelasblogger community's Instagram social media posts contain various values, such as commodity ​​and non-commodity values. The value of the commodity is detected in the XL Go MiFi modem purchased to support travelling activities. The use of information technology-based social media makes people have similar or uniform behaviour and compete in enjoying and spreading the sign values ​​in their lives. This consumptive behaviour is caused by several underlying factors, namely the development of lifestyle into a separate commodity, the shift from production to consumption, and capitalism's shift from labour exploration to consumer exploration.
Analisis Pemecahan Masalah Matematika Berbentuk Soal Cerita pada Materi SPLDV Ditinjau dari Gaya Kognitif
Authors: Faizah Hanim
Published: December 2022

Keterampilan pemecahan masalah sangatlah penting untuk pembelajaran matematika. Memecahkan masalah matematika membutuhkan strategi yang melibatkan proses kognitif dalam memahami masalah. Tujuan dari  penelitian ini merupakan bentuk deskripsi dari kemampuan siswa dalam menyelesaikan pemecahan permasalahan pada materi SPLDV ditinjau dari gaya kognitif. Jenis riset ini merupakan riset deskriptif kualitatif dengan memakai metode uji tulis serta tanya jawab. Subjek yang dipakai pada riset ini merupakan siswa VIII- F SMP PGRI 1 Buduran dengan 2 anak didik FD serta 2 anak didik FI. Instrument yang dipergunakan mencakup uji GEFT( Group Embedded Figures Test), lembar pertanyaan pemecahan masalah serta pedoman wawancara. Analisa informasi mencakup reduksi data, penyajian informasi serta penarikan kesimpulan. Hasil studi membuktikan subjek FD mampu membaca permasalahan, menguasai statment lisan dari kasus serta belum sanggup mengganti dengan bentuk perkataan matematika, menerima informasi lebih garis besar, tidak sanggup meluaskan hasil penyelesaian permasalahan serta kerap tidak memperoleh hasil yang tepat. Sebaliknya subjek FI mampu membaca permasalahan, menguasai statment lisan dari kasus serta mengubahnya ke wujud perkataan matematika, lebih analitis dalam menerima informasi, bertugas dengan idenya sendiri, bisa meluaskan hasil penyelesaian permasalahan serta memperoleh hasil yang tepat. Simpulan dari riset ini ialah individu FD cukup mampu penuhi indikator permasalahan Newman. Sebaliknya individu FI mampu penuhi indicator Newman.
Anterior transpetrosal approach for microvascular decompression associated with the dolichoectatic vertebrobasilar artery in two patients with refractory trigeminal neuralgia: Technical note
Authors: Segawa Masafumi , Inoue Tomohiro , Tsunoda Sho , Noda Ryuichi , Akabane Atsuya
Published: December 2022

Background:

Trigeminal neuralgia (TN) due to compression from the dolichoectatic vertebrobasilar artery (DVBA) is extremely rare and difficult to treat due to its morphological characteristics. We report two cases of good transposition of DVBA and postoperative course obtained using the anterior petrosal approach and a new vasoculopexy method.

Methods:

We describe two cases of microvascular decompression (MVD) for refractory TN associated with DVBA. In both cases, MVD was performed through the anterior petrosal approach. The DVBA was decompressed using a GORE-TEX sling and WECK clip in an inferomedial direction.

Results:

Complete pain relief without new neurological deterioration was achieved immediately in both patients.

Conclusion:

We experienced a rare condition of TN due to exclusion by the DVBA. The anterior transpetrosal approach was extremely effective in this case. This approach secured the surgical field, allowed transposition of the DVBA, and caused no perioperative complications.
A postoperative complication of lumbar discectomy: A discal/annular cyst
Authors: Saleemi M , Abrar Sahibzada , Dherijha Muhammad SA , George K. Joshi
Published: December 2022

Background:

A postoperative discal/annular cyst following lumbar discectomy may reproduce the symptoms/signs of a recurrent lumbar disc herniation (i.e., back pain and radiculopathy).

Case Description:

A 21-year-old rugby player developed leg pain after an uncomplicated lumbar microdiscectomy. The repeat lumbar magnetic resonance imaging confirmed a postoperative lumbar annular/ discal cyst, for which he underwent repeat surgery. The diagnosis was further confirmed histopathologically at surgery.

Conclusion:

Although rare, postoperative discal/annular cysts may be potential causes of recurrent postoperative pain and lumbar radiculopathy mimicking recurrent disc herniations.
APPLICATION OF THE (R, S) MODEL WHEN PLANNING STOCKS IN AN INDUSTRIAL ENTERPRISE
Authors: Kulyk Anatolii
Published: December 2022

One of the current problems in the enterprise management system is the creation and replenishment of stocks, the organization of continuous monitoring and prompt supply of raw materials. Using mathematical models, you can solve the problem of forming the optimal production program of the enterprise, investing in production, as well as to carry out strategic planning of enterprise development. In each case, it is important to build a model that describes the system under study, and on its basis to find the optimal ratio between costs and benefits of the selected level of stocks and determine what size stocks are sufficient. Correct inventory management allows you to maintain the production process and meet the needs of consumers in a timely manner. The purpose of this study is to build a model with a system with fully backordering, which is the optimal value of the stock level and the amount of average quarterly costs, which corresponds to the optimal value. Research methods are based on a probabilistic model of management approach for the enterprise. The method of building a model of inventory management system with periodic inspections was used, which found the average values of the intensity of demand for raw materials, unit costs and the cost of order verification. Depending on the initial values of the parameters, the optimal reserve of the quarterly stock is calculated, which corresponds to the given demand intensity. The study concludes on the value of the optimal level of stocks, as well as the average cost for the period corresponding to the regulatory level of stock.
MODERN PARADIGM OF STRATEGIC MANAGEMENT MECHANISMS OF THE ENERGY COMPANIES' DEVELOPMENT
Authors: Shvedkyi Volodymyr
Published: December 2022

The article defines the essence of strategic management of the energy company development and reveals its features in the energy sector. It is noted that the mechanisms of strategic management of the development of energy companies, in contrast to the mechanisms of tactical and operational management, include not only interacting elements in the form of management methods, methods and functions, but also strategies, procedures for their adjustment in the process of changes in the organization, defined and set goals , which meet modern challenges and allow to gain competitive advantages. The strategic management mechanisms of the energy companies development include infrastructural support; information provision and security; organizational support; regulatory and legal support; pricing; financial support; strategic development planning; energy saving motivation, etc. Infrastructural support in the energy sector is formed by transport operators and energy distribution systems. Information support is an effective mechanism of the strategic management system of energy companies development, the strengthening of which will allow to substantiate energy-efficient management decisions, contributes to their transparency, efficiency, consistency and timeliness. Organizational support of the energy sector of Ukraine is carried out by authorities that perform the following strategic management functions: development and implementation of strategic development policy and strategic concepts; development management of state-owned energy companies; regulation of the development of energy companies and the energy sector in general; coordination of activities in matters of energy security; organization of efficient production and use of energy resources in communities and regions. The scheme of regulatory and legal support for the development of energy companies of Ukraine in the context of strategic management is given. When considering pricing, the possibility of introducing a tariff based on the regulatory base of assets, or RAB-tariff, is being considered. Investigating financial support in the strategic management system, it is noted that the energy company must have a stable financial position, because the indicator of financial stability is a guarantor of reliability and invested funds return for investors. When considering the optimal financial support of energy companies, attention is drawn to the expediency of organizing a strategic planning system. Among the organizational and economic mechanisms of strategic management of the development of energy companies, the motivation of energy saving is singled out in order to stimulate and support the behavioral activity of employees in the direction of energy saving.
Relativistic coupled-cluster study of SrF for low-energy precision tests of fundamental physics
Authors: Talukdar Kaushik , Buragohain Haimyapriya , Nayak Malaya K. , Vaval Nayana , Pal Sourav
Published: December 2022

SrF, being a laser-coolable molecule, can be an interesting system for spectroscopic tests of fundamental physics. We present an electronic structure study of this molecule within the four-component relativistic coupled-cluster singles and doubles (RCCSD) framework and employ the RCCSD-based methods to compute its molecular-frame dipole moment and core properties such as hyperfine structure coupling constant and molecular P, T -odd electronic structure parameters that are of great importance for the high-precision tests of fundamental physics. The impact of basis set size, Hamiltonian and nuclear model on the property calculation of SrF is also investigated. The computed results are in good agreement with the available experimental values. The present study shows that the SrF molecule could be useful for high-precision molecular experiments to explore physics beyond the Standard Model of elementary particles.
Rosai-Dorfman Disease (Sinus Histiocytosis With Massive Lymphadenopathy): A Case Report
Authors: Ahmed Farooq , Moinuddin and R. G. Devani Mohammed
Published: December 2022

Sinus Histiocytosis with Massive Lymphadenopathy also known as Rosai-Dorfman Disease is a rare histiocytic proliferative disorder of unknown etiology. It presents as massive bilateral painless cervical lymphadenopathy. We report a case of RosaiDorfman disease in a 11 year old boy who presented with bilateral painless cervical lymohadenopathy. Only a few such cases have been reported in the literature hence this case is being reported for its rarity.
Anaesthesia Considerations for Dissecting Thoracic Aortic Aneurysm
Authors: Shah Swati
Published: December 2022

Surgical intervention is needed when the diameter of aorta increases more than 4.5 cm. Risk of rupture increases with diameter more than 6.0-6.5 cm. True aneurysm exhibits dilatation of all three layers of the aorta unlike pseudoaneurysm that involves only the adventitia. The risk of rupture is estimated by aortic size index. Dissection is classified as acute subacute and chronic depending on the duration of the disease. The condition is managed either by open surgery endovascular aortic repair or medically. Principle for open surgery is resection of the primary intimal tear with reapproximation of the intima and adventitia. Major anesthetic considerations involve the management of blood pressure monitoring amp prevention of vital organs ischemia such as heart lungs kidney and central nervous system amp control of bleeding.
Bed Bugs
Authors: S. Shankar P.
Published: December 2022

Bed bugs are blood sucking arthropod parasites and are found in tropical and temperate regions. They are small oval-shaped flat reddish brown wingless insects. They possess a segmented abdomen and exhibit ant-like movement. They mate by traumatic insemination. Bed bugs have adapted to the human environment. They get distributed from human travel. They bite human hosts and suck the blood. They feed during night times without being noticed. Bite of bed bugs result in cutaneous and systemic reactions. They are not known to transmit or spread diseases. Antihistaminics control urticarial itchy lesions. Improved cleanliness will help in the control of beg infestations.
Spurious Drugs: A Tragedy in Health System?
Authors: Jagadeesh and L. M. Abhijith K.
Published: December 2022

Counterfeiting is selling or marketing of non-genuine products as genuine under the name of famous manufacturer without the awareness of both real manufacturer of the product and the consumer. Drugs are consumed for prevention or treatment of disease and hence they provide optimal wellbeing for patients. If the drugs are counterfeited it leads to decreased prevention and treatment of the disease and to an increased morbidity and mortality. At the same time counterfeit drugs may make loss to the real manufacturer and the Government. Counterfeit drugs are one of the global major problems. It is seen in both the developing and developed countries. Drugs can be counterfeited by many ways from changing the concentration of the active ingredient to packing and labeling. The present article provides a brief overview of the present scenario of the counterfeit drugs in India and worldwide problems caused by the counterfeit drugs and the preventive measures taken to reduce the counterfeit drugs.
Tuberculoid Leprosy with Type 1 Lepra Reaction
Authors: Hanumanthayya K. , Balasubrahmanyam G. , Sohila and P. Saranya K.
Published: December 2022

None
Lesions of Large Intestine in Elderly Indians:Image Analysis
Authors: Subbarao Kakarla
Published: December 2022

None
PENILE FRACTURE
Authors: L Rokade Muktachand , V Kamat Nikhil , Kanbur Ajay
Published: December 2022

Penile fracture is a rare surgical emergency caused by rupture of tunica albuginea when an erect penis is subjected to unusual force. This condition requires prompt diagnosis and surgical treatment to preserve sexual function and to prevent deformity.
CURRENT CONCEPTS OF BRAINSTEM DEATH
Authors: S Shankar P
Published: December 2022

None
LAPAROSCOPIC UTERO-OVARIAN ARTERY ANASTOMOSIS POST-HYSTERECTOMY: A CASE REPORT
Authors: Neeta R. Sawat Rajkishor M Warty , Parul M Shah , Tanvi R Warty
Published: December 2022

A 45 years old patient diagnosed as multiple uterine fibroids underwent a Total Laparoscopic Hysterectomy. Anastomosis of ipsilateral uterine artery to ovarian artery on the right was performed. Right uterine artery was harvested from its origin and anastomosed to the right ovarian artery with 5-0 monofilament polypropropylene on 16 mm round body needleEthicon Johnson amp Johnson Aurangabad intermittent circumferential sutures. Patient was administered low molecular weight heparin post procedure followed by low molecular weight heparin and low dose aspirin for six weeks. A repeat ultrasonography with pelvic Doppler revealed an enhanced blood flow through the right ovarian pedicle as compared to the left reduction in the Pulsatility Index PI 3 months post-surgery. This procedure may be beneficial in cases of hysterectomy with ovarian conservation to prevent the occurrence of posthysterectomy ovarian failure as a consequence of vascular damage to the ovarian vasculature following hysterectomy.
DERMAQUIZ
Authors: D Fadia Racchana
Published: December 2022

None
An Exploratory study on violence in a rural area near Bengaluru, Karnataka, India
Authors: R Ramesh Masthi N , A R Manasa
Published: December 2022

Background In India there has been an increased reporting of violence over the years and its magnitude varies from state-to-state. Most of the studies available in India are on violence occurring within the household like domesticintimate partner violence child abuse etc. There are very few studies available on violence that occurs outside the household in the community.ObjectivesObjectives of the study were to assess the burden of violence among people living in a rural area near Bengaluru to list out the different types causes and health consequences of violence to assess the opinion of the subjects on violence and to find out the various factors associated with violence.MethodsThis exploratory study was conducted in the villages coming under three Primary Health Centres in a rural area near Bengaluru over a period of3 months in the last quarter of 2016. The Study subjects were aged between 14 years to 60 years. The total sample size was 2013. A pretested structured questionnaire was applied anonymously as the survey tool to gather information.ResultsA total of 2046 subjects were surveyed of whom 159 7.7 experienced some kind of violence in the past one year. 54 were males 32.1 were high school educated 14.5 had received no formal education 89.9 were Hindus. The major form of violence was verbal abuse 83.6 followed by pushing around 12.6 slapping 10.7 hitting 9.4. 5.0 had abrasions and 3.0 had bleeding and pain.ConclusionsAbout 7 of the subjects had experienced violence. Verbal abuse was the most common type of violence. Substance use was significantly associated with violence.
A Case report of ischaemic infarct secondary to vitamin B 12 deficiency induced hyperhomocystenaemia
Authors: Biradar Sangram , Reddy Rishika , Soogareddy Sumangala
Published: December 2022

nbspA 29 year old male presented with complaints of giddinessswayingnbsp tonbsp rightnbsp sidenbsp andnbsp numbness innbsp leftnbsp uppernbsp limbnbsp andnbsp lowernbsp limbnbsp sincenbsp 15daysnbsp Therenbsp wasnbsp onenbsp episodenbsp ofnbsp seizurenbsp withnbsp anbsp apostnbsp ictalnbsp confusionnbsp andnbsp diplopia. Magnetic resonance imaging MRI showed acute infarct in right posterior parietal cortex and subcortical white matter and right centrum semiovale. Magnetic resonance angiography MRA showed hypoplastic right anterior communicating artery ACA.nbsp Serum homocysteine levels were elevated and serum Vitamin B12 levels reduced.Stroke caused by hyperhomocysteinemia secondary to vitamin B12 deficiency is rare and preventable cause of ischaemic stroke.nbsp
Diphtheria and Pertussis in adults: Are we witnessing a shift in their epidemiology?
Authors: S Shankar P
Published: December 2022

None
Role of Wnt signaling pathway in type 2 diabetes mellitus: An overview
Authors: Rajeev Gandham , Delphine Silvia C.R. Wilma
Published: December 2022

The Wnt signaling pathway was discovered in 1982 by Nusse and Varmus during their breast cancer research. The key effect or of this pathway the bipartite transcription factor beta-catTCF is formed by free beta-catenin beta-cat and a TCF protein including TCF7L2. The Wnt signaling pathway regulates cell survival migration proliferation differentiation and organ development. Extensive recent investigations have shown that several key components of the Wnt signaling pathway are implicated in metabolic homeostasis and the development of type 2 diabetes mellitus. ThsWnt signaling is critical for glucagon like peptide-1 GLP-1 secretion by the intestinal endocrine L-cells. Thus alteration in this pathway could lead to reduced secretion of GLP-1 which in turn could have effect on insulin secretion. The GLP-1 in concert with insulin plays a critical role in blood glucose homeostasis. In this review we introduce background knowledge of Wnt signaling pathway and its role in type 2 diabetes mellitus.nbsp
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Authors: Nitin Mahurkar Dr.
Published: December 2022

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Effect of the Ethanolic Extract of Gloriosa superba Linn (Langli) Roots on theReproductive System of Female Rats
Authors: Malpani Arati , Mahurkar Nitin , Manjunath Chetan
Published: December 2022

Background The rhizome extract of Gloriosa superba Linn family Liliaceae is known to induce labor and facilitate normal delivery.Objective The present study was undertaken to assess the effect of ethanolic extract of Gloriosa superba Linn EyGS roots on the reproductive system of female Wistar rats.Material and Methods Immature ovariectomized OVX Wistar rats were administered EyGS orally at 20 and 40 mgkg body weight. Uterotrophic assay was performed to evaluate the effect of EyGS on estrogenic and progestogenic activity. The parameters evaluated were number of cornified cells in the vagina uterine weight and decidual weight. Biochemical parameters histopathology of the uterus and in vitro uterotonic activity were also assessed.Results Analysis of the effect of EyGS on vaginal cornification and deciduoma formation demonstrated vaginal opening without cornified cells decrease in uterine weight proliferation of uterus and reduction in deciduoma formation. EyGS produced decrease in the estrogen and progesterone levels and 80 contractions of the uterus compared to oxytocin.Conclusion The results indicate that the ethanolic extract of Gloriosa superba Linn had antiestrogenic and antiprogestogenic potential in OVX rats based on the physical histological and biochemical analyses. EyGS showed uterotonic activity in vitro and proves the folklore use of Gloriosa superba Linn.Keywords Gloriosa superba uterotrophic assay estrogenic vaginal cornification
Effect of Aqueous Leaves Extract of Melia Azedarach Linn. on Experimental Colitis in Rats
Authors: Mansoor Ahmed Syed , Nizamuddin Darvesh Mohammad , Eranna Manjunatha , Rudrappa Nandeesh
Published: December 2022

Ulcerative colitis is one of the subtypes of inflammatory bowel disease IBD is characterized by confluent mucosal inflammation of the colon. It usually aggravated by an imbalance between destructive and defensive factors in the intestine. Melia azedarach Linn of family Meliaceae is a medicinal plant having traditional and medicinal repute rich in various bioactive phytoconstituents and also reported to possess anti-bacterial anti-pyretic anti-oxidant and anti-malarial activity.The present study was conducted to elucidate the ameliorative effect of aqueous leaves extract of Melia azedarach Linn. on Indomethacin induced colitis in male wistar rats. The animals were administered with inducer Indomethacin 7.5 mgkg and standard drug Sulphasalazine. The aqueous extract of leaves Melia azedarach administered at a dose of 200 400 mgkg p.o. Ulcer area ulcer index colon weight to length ratio macroscopic score haematological parameters colonic superoxide dismutase SOD glutathione GSH myeloperoxidase MPO malondialdehyde MDA and histological changes were recorded after the treatment regimen of 12 days.Subcutaneous instillation of indomethacin caused enhanced ulcer area ulcer index colon weight to length ratio colonic MPO MDA it caused significant decreased level of SOD and GSH. Pre-treatment with aqueous extract of leaves Melia azedarach for 12 days exhibited significant effect in lowering of oxidative stress colonic and elevation of SOD and GSH at a dose of 200 and 400 mgkg in Indomethacin induced colitis. The present investigation demonstrates Melia azedarach Linn. is of potent therapeutic value in the amelioration of experimental colitis in laboratory animals.
A Brief Review on Pharmacological Profile of Zingiber officinale
Authors: Sindhoora D , Bhattacharjee Ananya
Published: December 2022

Ginger Zingiber officinale Roscoe Zingiberacae is a medicinal plant that has been widely used in Chinese Ayurvedic and Tibb-Unani herbal medicines all over the world. Ginger is known for its numerous scientific properties and has been appreciated in various parts of the globe for the last 2500 years. Ginger has rich phytochemistry and many viewpoints that support wellbeing. Immunomodulatory anti-tumorigenic anti-inflammatory anti-apoptotic anti-hyperglycemic anti-lipidemic and anti-emetic activities are the key pharmacological actions of ginger and compounds derived from it. Ginger is a powerful antioxidant agent that can either reduce or prevent free radicals from being produced. It is considered a healthy herbal medication with few adverseside effects that are insignificant. There is currently a renewed interest in ginger as well as many scientific studies aimed at the isolation and detection of the active constituents of ginger the scientific verification of its pharmacological activity and its constituents and the verification of the basis for the use of ginger in a variety of different diseases and conditions.
Factorial Design Based Optimisation of Metoclopramide Hydrochloride Fast Dissolving Tablets
Authors: Md Sarfaraz , Dhanalakshmi B. , Doddayya H. , Arshad Ahmed Khan K.
Published: December 2022

Aim of the study The present investigation was aimed at developing taste masked fast dissolving tablets FDT of metoclopramide hydrochloride using 23 factorial design model.Materials and methods Metoclopramide hydrochloride is used as antiemetic drug and is intensely bitter in taste. The bitterness of drug was reduced by using a combination of flavour and complexing with beta-Cyclodextrins.The taste masking ability of complex was evaluated in healthy human volunteers. The taste masked fast dissolving tablet was developed by direct compression method using superdisintegrants like sodium starch glycolateSSG croscarmellose sodium CCS and crospovidone CP in different concentration as per 23 factorial design model.Results and conclusions The physico-chemical properties of tablets were evaluated prior to in vitro release studies. The hardness 4.7plusmn0.12 - 5.0plusmn0.20 kgcm2 friability 0.07plusmn0.22 - 0.83plusmn0.24 drug content 9.40plusmn0.36 - 10.46plusmn0.21 mg and disintegration time 8.24plusmn0.46 - 90.00plusmn0.70 sec of FDT were found uniform and acceptable as per limits. ANOVA was used to determine the significant effect. The model was found to be significant at the level of probability plt0.05 for disintegration time and also dissolution rate as well. From contour plots obtained the formula of optimized tablet was predicted. The optimised concentration of superdisintegrants was 15.6 mg of SSG 9.80 mg of CCS and 9.40 mg of CP. Optimised formula F9 gave disintegration time of 8.24plusmn0.46 sec and 99.262 of drug release. The formulations followed first order mechanism of release r20.793 ndash 0.926.
Evaluation of Alpha-Amylase Inhibitory and Antidiabetic Potential of Novel 1,3,4-Oxadiazole Derivatives
Authors: Hussain Mukinur , Chikkamath Vinuth , Ittagi Shanmukha
Published: December 2022

Oxadiazoles are the heterocyclic compounds containing one oxygen and two nitrogen atoms in a five membered ring possessing a diversity of useful biological effects. 134-oxadiazole is one of the most important heterocyclic moieties has wide spectrum of therapeutic activities. The activities include anticancer antimicrobial anti-inflammatory anti- HIV antitubercular antidiabetic and antifungal. The present study aims to assess the in-vitro alpha amylase inhibitory and in-vivo antidiabetic activity of some novel 134-oxadiazole derivatives. The synthesized oxadiazole derivatives SOZDs viz. SOZD1 SOZD2 SOZD3 SOZD4 and SOZD5 were evaluated for the amylase inhibition and alloxan-induced diabetic rat model. The assessment parameters are body weight fasting blood glucose FBG lipid profile enzymes and pancreas histopathology. Alphalpha-amylase inhibition assay depicted that maximum inhibition was observed at the concentration of 7000 mugml. Furthermore SOZDs treated diabetic rats show significant depletion in serum FBG urea and creatinine levels. There were statistical differences between the diabetic control and SOZD treatment groups with regard to lipid profile enzymes. Besides SOZDs reinforce the healing of alpha and beta cells of the pancreas in diabetic rats. It is evident from results that SOZD4 and SOZD5 derivatives showed a significant improvement of body weight blood parameters and lipid profile enzymes. Hence the findings of our study delineated SOZD4 and SOZD5 could be emerging as potential molecules for diabetic patients.
A (des)ordem do corpo: costuras entre moda e gênero
Authors: Tavares de Carvalho Pâmela , Carmona Garcia Luciana
Published: December 2022

O presente artigo, ancorado nos estudos discursivos, a partir do método arquegenealógico engendrado por Michel Foucault, tem como objetivo observar os mecanismos que constroem o corpo dito e visto nas linhas históricas, sociais e culturais como masculino, nas redes discursivas da Moda. De início contextualizamos a noção de acontecimento para que fosse possível tomar os enunciados que, em diferentes ordens, selecionam, organizam e redirecionam os discursos que falam sobre o homem e/ou a mulher. Em seguida, procuramos demonstrar como o corpo - e seus significantes e significados - tem sido o objeto pelo que se luta no espaço da Moda. O corpus para o qual se volta nosso olhar analítico é formado por um ensaio-reportagem publicado pela revista Manchete, edição número 0652, ano de 1964, no qual fora possível observar que a Moda, ao inscrever-se na desobediência do corpo, pode ser capaz de (re)modelar-se na multiplicidade do masculino e do feminino, desestabilizando ‘verdades’ sobre as políticas determinantes do corpo, do gênero e das subjetividades.
Das técnicas do desfilar aos vazamentos corporais
Authors: Costa Leahy Renata
Published: December 2022

Este artigo pretende abordar os corpos dos desfiles de moda a partir da compreensão do corpo como uma força sensório-motora expressiva, que nos permite considerar, em meio à visível uniformidade de performances nas passarelas, nuances das especificidades compositoras de tais aparições. Assim, apresentaremos a noção de vazamentos corporais, defendida na tese Metáfora do Cabide: corpo e aparição nos desfiles de moda (LEAHY, 2018), sobretudo a partir das noções de técnicas do corpo, do sociólogo e antropólogo Marcel Mauss (2003), e de esquema corporal, do filósofo fenomenólogo Maurice Merleau-Ponty (1999). Após situarmos as formas pelas quais os corpos vestidos realizavam suas performances nos desfiles até os modos contemporâneos, tratamos da questão das técnicas corporais utilizadas especificamente na atividade dos corpos nas passarelas, que podem ser compreendidas como técnicas do desfilar. A partir de breves exemplos de desfiles da São Paulo Fashion Week 42 (SPFW42) do ano de 2016, analisados na tese2, vamos perceber e discutir sobre os vazamentos operados e expressos por esses corpos, reconhecendo-os como elaborados em uma cultura, agenciados como potências sensíveis e motoras.

2Os desfiles analisados foram: Animale, Lab, Água de Coco e Ronaldo Fraga.