bluuebunny/crossref_metadata_2025 huggingface dataset:
Study the Relationship of PCSK9 Gene Polymorphism and PCSK9 Protein on Serum Bad Cholesterol and Risk of CVDs in Iraqi Patients
Authors: Abdulkareem Rafid A. , Khaleel Anas Abdaljaleel
Published: June 2021

Cardiovascular disease responsible for number 1 of death worldwide. Many genetic and environmentalfactors influence the development of CVDs. PCSK9 protein responsible for degradations of LDLRwhich lead to increase blood level of bad cholesterol. Gain of function mutation in PCSK9gene result inhypercholesterolemia and loss of function lead to hypocholesterolemia. Aim of this study: to investigatethe polymorphism of rs775278198 of PCSK9 gene and serum level of PCSK9 with their effect on LDL-Clevel in CVDs patients. Materials and methods: a common SNP PCSK9 gene was studied using Real-Time PCR and technique to show association between PCSK9 SNP with risk of developing CVDs. fifty ofcardiovascular diseases patients who were clinically diagnosed by physicians and fifty apparently healthyindividuals were conducted within this study. Blood samples were collected from all subjects after overnightfasting. Genomic DNA was extracted from blood samples and analyzed for rs775278198 SNP in PCSK9gene with specific primers and probes using Real-Time PCR technique. Also, serum levels of PCSK9 wereevaluated using Elisa kit supplied by Bioassay Technology Laboratory. In addition LDL-C levels weremeasured by lipid profile test kit (CHOL2) supplied by Roch. Identification of PCSK9 SNP polymorphismand PCSK9 serum levels with LDL-C levels in this study success percentage of the methods. Results: inReal Time PCR, CVDs patients appeared the TT (20 vs 4, OR=6, p=0.028) genotypes were significantlyhigher in patients when compared to controls group (20 vs 4%, OR=6, P=0.028) .In comparison of theserum levels of PCSK9 in CVDs patient were higher than PCSK9 serum levels in controls group (p value=f0.000005) at the same time there is a positive relationship between PCSK9 serum levels and LDL-C levelsas measured by Pearson Correlation.
Whether or Not A Shunt is Placed in the Brain (Pre/Post Repair) for Patients with a Lumbar Meningocele and Hydrocephalus Undergoing a Lumbar Meningocele Procedure
Authors: Ali Abbas Hashim Almusawi
Published: June 2021

This study involves the important comparison in doing V-P shunt operation before surgical correction and repair to the neonates born with spinal dysraphism meningocele at the lumber region versus doing V-P shunt after repair of neural tube defect meningocele to avoid post operative (correction of neural tube defect) leaking cerebrospinal fluid and surgical wound infection.The study 50 newborn babies with hydrocephalus and spinal dysraphism meningocele.
GATA 3 Reactivity in Adenoid Cystic Carcinoma and Pleomorphic Adenoma of Salivary Glands
Authors: Ali Zaki NAJI  , Ammar Eesa Mahdi
Published: June 2021

Objectives:The main targets is evaluate clinicopathological distribution and comparison of immunohistochemical (IHC) expression of GATA 3 between in adenoid cystic carcinoma (ACC) and pleomorphic adenoma (PA) of salivary . Design and Methods: This retrospective analysis, open surgical specimens of salivary gland that were done , and consisting of 150 cases that divided into three groups: normal salivary gland tissues (n=50), adenoid cystic carcinoma(n=50), and pleomorphic adenoma(n=50). Clinical data (age, sex, previous diseases ), physical examination, and investigations are done for all patients. In addition.These 150 cases of paraffin embedding blocks of salivary tissue were stained by ordinary stained (hematoxylin and eosin staining ). Manual IHC staining of GATA 3 was done. Results: Age groups is younger for normal salivary gland tissues than PA, and ACC . Sex distribution was slightly increase in male in comparison to female in normal salivary gland tissues and PA. GATA 3 staining was showing more positivity in normal salivary gland tissues (43/50 patients) than PA (27/50 patients) and ACC (14/50 patients). This positivity in GATA 3 IHC staining were more in male sex, regarding 55.8% in normal salivary gland tissues than ACC50% and PA 51.9% . Age group 31-40, 40-50 and 61-70 years were showing more positive GATA 3 IHC staining in normal salivary gland tissues, PA, and ACC respectively. there was insignificant association between GATA 3 IHC staining with either age groups or sex groups distribution .Conclusion: GATA3 IHC is good marker and can used for searching salivary gland tumor origin, assisting in diagnosis Salivary gland tumors subtypes but GATA3 IHC staining has no association to specific sex or age groups in Salivary gland tumors. Usage of surgical operations for histopathological specimens preparation are better and give good efficiency for IHC markers staining.
Molecular Association of Sexually Transmitted Infections and Methylation Pattern of SNRPN Gene Promoter among Males with Abnormal Semen
Authors: Noor AL-Hamid  , Abdul Kareem AL-Kazaz
Published: June 2021

Infertility affects about 8-12% of couples worldwide, and male infertility accounts for a half of these cases, therefore, thisstudy was undertaken to focus on some factors affecting male’s fertility such as DNA methylation and genital tract infections by sexually transmitted diseases. The study groups included infertile males as a patient group (n=63) in an age mean (32.28 ± 6.88 years) and fertile males as a control group (n=13)in an age mean (34.07 ±6.52years).Seminal fluid was collected from all males attending a clinical laboratory for routine semen analysis, seminal fluid analysis was performed according to World Health Organization guidelines, all of the 63 infertile males was suffering from reduced sperm concentration (9.42 ± 8.70 million/ml), reduced progressive motility (2.89 ± 5.45%) and abnormal sperm morphology (27.06 ± 16.50%), while control group have a higher values thus, there was a highly significant difference in semen parameters between the two groups.The DNA samples of the patients group (n=44) and control group (n=13) was subjected to bisulfite treatment to convert un-methylated C-residues to uracil, this step was performed to allow the qualitative detection of methylation at the promoter of Small nuclear ribonucleoprotein polypeptide N gene by Real time polymerase chain reaction using two sets of designed primers (methylated and un-methylated sets) allowing one set of the primers to anneal, and amplify the desired region.The results of real time PCR for the detection of methylation in SNRPN gene promoter showed hyper methylation in the promoter of SNRPN in some samples (22.7%), a slight methylation in others (20.4%) and no methylation in other samples (56.8%) from infertile males, while all the 13 control samples showed no methylation.
Determination of Vitamin D Concentration in Diabetic and Non Diabetic Men and Its Correlation with Age
Authors: Abdulhadi M. Jumaa  , Meqdam Atiyah Khalaf  , Hassan Yashar Hassan
Published: June 2021

Background Vitamin D is synthesized from precursors” present at the surface of the epidermis and then undergo biotransformation which achieved at the hepatocytes and finally by hydroxylation enzymes in the nephrons “ . “sunrays play a crucial role in the beginning of D vitamin formation processes, parathyroid hormone is an essential hormone secreted by parathyroid glands and play a key role in the activation of D vitamin by renal alfa hydroxylase”. Food sources of D vitamin are also important for supplementation of human body with some requirements. This Study Aimed to compare the concentration of vitamin D in diabetic patients, and non-diabetic men and its association with age.Patients and Methods the current study started at the beginning of june 2018 and continued until the end of March 2019 , at the outpatient unit in especial private hospital at Tikrit city - Iraq. Eighty men have been enrolled in present study.Results Eighty men were participate in the present study, distributed as 40 non diabetic subjects as controls and 40 diabetic patients. The mean and standerad deviation of D vit. levels of non-insulin dependant diabetes and normal physically fit men show there is significant reduction of D vit. Measurements of the diabetic men patients suffering from T2DM, (13.58 ± 5.29) as compared with control subjects, (19.95 ± 6.5). there are significant decrease of vit. D measurements of T2DM young patients. In T2DM patients less than 18 years old have significant reduction in vitamin D concentration, (13.41 ± 5.1), as compare with T2DM patients aged 18-40 years, (17.23 ± 7.3). Measuremets of D vit. Durind heat season and compare to cold months.The evaluation of D vit. During hot monthes show significant rise(26.4 ± 7.1) in comparison with winter status(13.65 ± 4.2). Conclusions the present study conclude that, D vit. Levels show highly important increament in hot months as compare with winter season and there are significant reduction in the concentration of vitamin D in young age type 2 diabetic patients
ASSOCIATION FORMATION TECHNIQUE IN PRESCHOOL CHILDREN
Authors:   Master of Preschool Education, Navai State Pedagogical Institute, Uzbekistan, Navai, Rakhmatova Gulobod
Published: June 2021

This article discusses association formation technique in preschool children. Language is a linguistic structure with a multifaceted complex structure. It is natural for a person to influence the use of language, to try to "express it in their own way." Instead, language is also a powerful force that helps regulate a person's social life. Such a relationship between the language and the person who uses it, of course, does not go unnoticed in the language. One of the methods that serves to determine the richness of the human vocabulary, its formation and development, is the method of associative experiment.
THE ROLE OF "SPIRITUALITY" AND "ETHICS" CATEGORY IN THE DEVELOPMENT OF THE UZBEK LANGUAGE
Authors:   Lecturer, Shahrisabz branch of TSPU named after Nizami, Bobojonova Shohsanam Sharifboyevna
Published: June 2021

This article reflects the role of spirituality and morality in the spiritual development of young people. The role and importance of national spirituality in the life and development of society is widely covered.
Thermal Analysis and Computer Aided Exhaust Valve Design Automation Using CREO and Microsoft Excel Spreadsheet
Authors: Chabru Siraj , Kulkarni P. S.
Published: June 2021

3D modeling has widely been used because of their ease in visualization, understanding and generation of manufacturing drawing sheets compared to 2D drafting. 3D Modeling is the timeconsuming process and many draftsmen does not have the skill to draw a 3D object inside a CAD packages. Internal combustion engine consists of two type of valves inlet valve and exhaust valve. The pair of inlet and exhaust valve is called as poppet valves. Exhaust valve is the mechanical object reputedly required nearly in all internal combustion engines. In this paper we are automate the exhaust valve design by creating graphical user tool using visual basic programming language inside the Microsoft excel spreadsheet. This excel spreadsheet is later integrated to CREO database for automatic 3D valve Modeling. Exhaust valve is the nose of the internal combustion engine to eject the exhaust gases out form the engine at a time of exhaust stroke. It is continuously come under the high temperature and pressure. Steady state thermal analysis has been carried out using FEA. To demonstrate our study, we are considered to design and analysis the exhaust valve for Honda CB Twister 110cc having chamfer angle of 45 degrees. For the 3D modeling we use CREO and ANSYS 18.0 is used for FEA analysis.
Senegal Farmer Networks Respond to COVID-19
Authors: Latané Annah , Voisard Jean-Michel , Brower Alice Olive
Published: June 2021

This study leveraged existing data infrastructure and relationships from the Feed the Future Senegal Naatal Mbay (“flourishing agriculture”) project, funded by the US Agency for International Development (USAID) and implemented by RTI International from 2015 to 2019. The research informed and empowered farmer organizations to track and respond to rural households in 2020 as they faced the COVID-19 pandemic. Farmer organizations, with support from RTI and local ICT firm STATINFO, administered a survey to a sample of 800 agricultural households that are members of four former Naatal Mbay–supported farmer organizations in two rounds in August and October 2020. Focus group discussions were conducted with network leadership pre- and post–data collection to contextualize the experience of the COVID-19 shock and to validate findings. The results showed that farmers were already reacting to the effects of low rainfall during the 2019 growing season and that COVID-19 compounded the shock through disrupted communications and interregional travel bans, creating food shortages and pressure to divert seed stocks for food. Food insecurity effects, measured through the Household Food Insecurity Access Scale and cereals stocks, were found to be greater for households in the Casamance region than in the Kaolack and Kaffrine regions. The findings also indicate that farmer networks deployed a coordinated response comprising food aid and access to personal protective equipment, distribution of short-cycle legumes and grains (e.g., cowpea, maize) and vegetable seeds, protection measures for cereals seeds, and financial innovations with banks. However, food stocks were expected to recover as harvesting began in October 2020, and the networks were planning to accelerate seed multiplication, diversify crops beyond cereals, improve communication across the network. and mainstream access to financial instruments in the 2021 growing season. The research indicated that the previous USAID-funded project had likely contributed to the networks’ COVID-19 resilience capacities by building social capital and fostering the new use of tools and technologies over the years it operated.
Castro Rodolfo Norberto y otro c/ Ordiz Osvaldo Martín y otros | daños y perjuicios
Authors: CNCiv.
Published: June 2021

Tribunal: Cámara Nacional de Apelaciones en lo Civil

Sala / Juzgado / Circunscripción / Nominación: D

Partes: Castro Rodolfo Norberto y otro c/ Ordiz Osvaldo Martín y otros s/ daños y perjuicios

Fecha: 9 de marzo de 2020
New species of the genus Pseudamnicola from Kythira Island (Mollusca: Gastropoda: Hydrobiidae)
Authors: Glöer Peter , Porfyris Anastasios
Published: June 2021

Recent investigations of hydrobiids from Kythira Island (Greece) revealed two Pseudamnicola species, P. magdalenae Falniowski 2016, already sequenced by Szarowska et al. (2015), and an unnamed species of the latter genus. The aim of this paper is to describe the new species of the genus Pseudamnicola from Kythira Island.
Glass Foam Made with Silicon Nitride and Manganese Oxide by Microwave Irradiation
Authors: Dragoescu Marius Florin , Paunescu Lucian , Axinte Sorin Mircea
Published: June 2021

A high mechanical strength (6.1 MPa) glass foam was produced by sintering/foaming at 830 ºC in an experimental 0.8 kW-microwave oven. The basic raw material was a colorless flat glass waste and the foaming agent was Si3N4 powder (2 wt.%). As an oxygen supplying agent, a MnO2 powder (3.1 wt.%) was used. The main physical, mechanical, thermal and morphological characteristics of the optimal sample were: apparent density of 0.47 g/cm3, porosity of 77.6%, thermal conductivity of 0.105 W/m·K, compressive strength of 6.1 MPa and pore size between 0.15-0.40 mm. The optimal glass foam sample has the required characteristics of a thermal insulation material usable under mechanical stress conditions in civil engineering. The originality of the paper is the application of the unconventional microwave heating technique, faster and more economical, unlike the other papers in the same area published in the literature, followers of the traditional conventional heating technique.
Multiepoch Optical Images of IRC+10216 Tell about the Central Star and the Adjacent Environment
Authors: Kim Hyosun , Lee Ho-Gyu , Ohyama Youichi , Kim Ji Hoon , Scicluna Peter , Chu You-Hua , Mauron Nicolas , Ueta Toshiya
Published: June 2021

Six images of IRC+10216 taken by the Hubble Space Telescope at three epochs in 2001, 2011, and 2016 are compared in the rest frame of the central carbon star. An accurate astrometry has been achieved with the help of Gaia Data Release 2. The positions of the carbon star in the individual epochs are determined using its known proper motion, defining the rest frame of the star. In 2016, a local brightness peak with compact and red nature is detected at the stellar position. A comparison of the color maps between 2016 and 2011 epochs reveals that the reddest spot moved along with the star, suggesting a possibility of it being the dusty material surrounding the carbon star. The relatively red, ambient region is distributed in an Ω shape and corresponds well to the dusty disk previously suggested based on near-infrared polarization observations. In a larger scale, differential proper motion of multiple ring-like patterns in the rest frame of the star is used to derive the average expansion velocity of transverse wind components, resulting in ∼12.5 km s−1(d/123 pc), where d is the distance to IRC+10216. Three-dimensional geometry is implied from its comparison with the line-of-sight wind velocity determined from half widths of submillimeter emission line profiles of abundant molecules. Uneven temporal variations in brightness for different searchlight beams and anisotropic distribution of the extended halo are revisited in the context of the stellar light illumination through a porous envelope with postulated longer-term variations for a period of ≲10 yr.
An 86 GHz Search for Pulsars in the Galactic Center with the Atacama Large Millimeter / submillimeter Array
Authors: Liu Kuo , Desvignes Gregory , Eatough Ralph P. , Karuppusamy Ramesh , Kramer Michael , Torne Pablo , Wharton Robert , Chatterjee Shami , Cordes James M. , Crew Geoffrey B. , Goddi Ciriaco , Ransom Scott M. , Rottmann Helge , Abbate Federico , Bower Geoffrey C. , Brinkerink Christiaan D. , Falcke Heino , Noutsos Aristeidis , Hernández-Gómez Antonio , Jiang 江 Wu 悟 , Johnson Michael D. , Lu 路 Ru-Sen 如森 , Pidopryhora Yurii , Rezzolla Luciano , Shao Lijing , Shen 沈 Zhiqiang 志强 , Wex Norbert
Published: June 2021

We report on the first pulsar and transient survey of the Galactic Center (GC) with the Atacama Large Millimeter/submillimeter Array (ALMA). The observations were conducted during the Global Millimeter VLBI Array campaign in 2017 and 2018. We carry out searches using time series of both total intensity and other polarization components in the form of Stokes parameters. We incorporate acceleration and its derivative in the pulsar search, and also search in segments of the entire observation to compensate for potential orbital motion of the pulsar. While no new pulsar is found, our observations yield the polarization profile of the GC magnetar PSR J1745−2900 at millimeter wavelength for the first time, which turns out to be nearly 100% linearly polarized. Additionally, we estimate the survey sensitivity placed by both system and red noise, and evaluate its capability of finding pulsars in orbital motion with either Sgr A* or a binary companion. We show that the survey is sensitive to only the most luminous pulsars in the known population and future observations with ALMA in Band-1 will deliver significantly deeper survey sensitivity on the GC pulsar population.
Revision of the genus Coccidula Kugelann (Coleoptera, Coccinellidae)
Authors: Szawaryn Karol , Nedvěd Oldřich , Biranvand Amir , Czerwiński Tomasz , Nattier Romain
Published: June 2021

The genus Coccidula Kugelann includes five species distributed in the Holarctic, with one species in North America and four in Palearctic region. Coccidula belongs to the tribe Coccidulini which historically was treated as a separate subfamily within ladybird beetles, but recent studies confirmed its placement as a tribe within the broadly defined subfamily Coccinellinae. All species are revised and a new synonymy of Lithophilus naviauxi Duverger with C. litophiloides Reitter is proposed. Light and electron microscopy pictures support morphological descriptions. An identification key to all species is also provided.
Le théâtre à l’école en France : une potentialité au service des apprentissages ?
Authors: Sanchez Lisa , Creissen Sara , Blanc Nathalie
Published: June 2021

Quelle est la place du théâtre dans le système scolaire français, en tant qu’outil pour contribuer aux apprentissages et au bien-être des élèves ? Cet article vise à répondre à cette question en prenant appui sur une étude menée au Québec (Dubois & Tremblay, 2015) dans le but d’établir la place du théâtre dans les pratiques enseignantes. Reprenant leur méthodologie d’analyse appliquée au cas français, la première contribution de cet article réside dans le décalage observé entre les recommandations ministérielles et les formations proposées aux enseignants les préparant à l’utilisation du théâtre en milieu scolaire. Partant de ce constat, la deuxième partie de l’article est consacrée à la présentation des résultats de travaux en faveur de cette mobilisation du théâtre en contexte scolaire. Les pratiques d’utilisation du théâtre à l’école sont envisagées dans toute leur diversité, avec des travaux qui rapportent des bénéfices pour les élèves, tant sur le plan cognitif que motivationnel. Forte des résultats déjà disponibles, la pratique du théâtre en milieu scolaire est avancée comme une ligne de recherche prometteuse au service d’un meilleur développement des élèves.
Retard de croissance et retard de développement chez les enfants d’Afrique sub-saharienne
Authors: Dembélé Bernard , Amadou Sanni Mouftaou
Published: June 2021

Le retard de croissance a des effets négatifs sur le développement des enfants. En revanche, la stimulation protège du retard développemental. L’objectif de cette étude est d’évaluer dans quelle mesure le sexe des enfants module ces relations en Afrique sub-saharienne. L’analyse utilise les données groupées des dernières enquêtes démographiques et de santé du Cameroun, du Congo-Brazzaville, du Tchad et du Togo. La définition du statut développemental s’appuie sur l’index de développement précoce des enfants à 3-4 ans et l’évaluation de la stimulation sur des activités d’éveil physique et psychologique regroupées en 6 catégories. Les modèles explicatifs utilisés sont le probit simple et bivarié. Globalement, deux enfants sur cinq sont en retard de croissance, avec une prévalence équivalente entre sexe. Plus de la moitié des enfants connaissent à des degrés divers un problème développemental, accentué pour les garçons. Les effets du retard de croissance sur le retard développemental de l’enfant sont notables surtout pour le jeune garçon, mais ils sont atténués par le recours à la stimulation active dès l’enfance. La robustesse des résultats fondés sur quatre pays devrait inciter la promotion des activités de stimulation dans un contexte de prévalence élevée du retard de croissance et de retard développemental.
Mesurer la spécificité de deux communautés étatsuniennes avant la guerre de Sécession : Sainte-Geneviève et Potosi, Missouri
Authors: Villerbu Soazig
Published: June 2021

Sainte-Geneviève et Potosi sont deux petites villes du sud-est du Missouri qui ont, comme particularité, d’avoir leurs origines dans le peuplement colonial français de la région et d’avoir cru en une croissance mirifique dans les années 1800 et 1810. Mais cette croissance n’est jamais réellement venue et l’objectif de cette étude est donc de mesurer en quoi leur destin peut être qualifié de spécifique en le comparant d’abord avec ceux d’autres petites villes de la région et en scrutant ensuite leur développement propre (structures sociales, niveaux de fortune, mobilités) en fait autant marqué par de réelles convergences que de fortes différences, alors que les armées de l’Union qui les occupent en 1861 n’y voient guère que des villes rebelles à mater.
La fonte au cœur du modèle mussipontain (1856-1970)
Authors: Lamoureux Carole
Published: June 2021

Créée en 1856, la société Pont-à-Mousson (PAM) produit de la fonte brute avec pour principal débouché les tuyaux d’adduction d’eau et de gaz. En 1970, lors de la fusion avec Saint-Gobain, ces activités demeurent centrales pour son identité et sa stratégie. À plus d’un égard, le choix initial de la fonte, constamment renouvelé, semble avoir orienté le modèle industriel de l’entreprise. Avant 1914 s’est en effet déployé un modèle axé sur l’écoulement de la fonte brute jusque sur les marchés d’exportation. Le tuyau en fonte rencontre cependant la concurrence croissante de l’acier. Tandis que le ciment et le béton montent également en gamme, PAM s’empare d’une innovation qui lui confère un avantage technique et commercial : la fonte ductile.
« Tramway à deux sous », naissance d’une politique du transport public urbain : une tentative du premier maire socialiste de Marseille, Siméon Flaissières (1892-1902)
Authors: Kokubu Hisao
Published: June 2021

Les réseaux de tramways en France se sont développés depuis les années 1890. À Marseille, le premier maire socialiste Siméon Flaissières commença dès le 1 er  janvier 1900 une politique du transport public urbain, introduisant le système du « tramway à deux sous » et l’électrification totale du réseau. Le système de la concession fut assez profitable à la municipalité afin de réaliser le « socialisme municipal » dans les services publics de transport. Cette politique de Flaissières a été relativement efficace sur le plan des résultats électoraux et lui a permis de gagner les élections municipales de 1900. Pourtant, son effet politique ne fut pas durable. En effet, dès l’année 1902, un grand nombre d’électeurs de quartiers ne lui avait plus donné leurs faveurs.
Le métropolitain d’Hector Guimard : un Art nouveau officiel
Authors: Montamat Bruno
Published: June 2021

Le formidable élément de développement urbain que fut le métropolitain parisien, construit à une époque charnière de la mobilité humaine, est aisément reconnaissable dans le monde entier par l’esthétique novatrice de ses édicules et entourages d’entrée. Créés en 1900 par l’« architecte d’Art » Hector Guimard, ils constituent une véritable signature visuelle de ce mode de transport populaire par leur qualité graphique et leur dynamisme formel. Les différentes récupérations mémorielles que connue l’histoire complexe du métro contribuèrent à une légende noire de l’Art nouveau, attisée par l’artiste lui-même, qu’il s’agit aujourd’hui de réétudier finement, hors de tout travail hagiographique. Animée par la patrimonialisation de la capitale, l’union de l’État et de la Ville de Paris joint à l’intérêt commercial d’une société privée belge pour sa réalisation, apparaît comme un exemple réussi d’habilité politique en faveur d’un art moderne pour tous, mise en œuvre par le rationalisme symbolique du « style Guimard ».
Le déterminant démonstratif ce : d’un marqueur token -réflexif à une instruction contribuant à la construction de référents
Authors: De Mulder Walter
Published: June 2021

L’objectif de cet article est de voir dans quelle mesure on peut se servir des idées sous-jacentes à l’approche socio-cognitive qui a récemment été appliquée à l’analyse du fonctionnement des SN démonstratifs complexes ce N-ci et ce N-là pour repenser le sens et le fonctionnement des SN démonstratifs introduits par ce . Il est conclu que le sens du déterminant démonstratif ce doit toujours être défini à l’aide de la notion de token -réflexivité mais que les idées de l’approche socio-cognitive permettent de compléter l’interprétation du SN démonstratif conformément à l’indication que le référent du SN démonstratif doit être identifié à partir d’éléments dans le contexte de son occurrence.
Ça et là : formes privilégiées de reprise méta-discursive dans l’interaction orale
Authors: Grobet Anne
Published: June 2021

En adoptant une perspective cognitive sur l’anaphore et en s’appuyant sur l’analyse d’extraits d’interactions, l’article décrit les spécificités d’emplois oraux de là et de ça tout en expliquant la fréquence de leur utilisation méta-discursive. Si ces deux formes ont en commun de pouvoir être décrites comme des anadéictiques, leur fonctionnement diffère : là opère un fléchage sur le discours antérieur, opérant un cadrage spatio-temporel ou énonciatif pouvant être associé à un changement de topique ou de cadre participatif, tandis que ça opère un pointage indexical qui, combiné à des structures syntaxiques segmentées, indique une forte topicalité, en lien avec l’implication du locuteur.
L’urbanisation subalterne en Inde
Authors: Zérah Marie-Hélène , Denis Éric , Mukhopadhyay Partha
Published: June 2021

En Inde où vit un dixième des citadins de notre planète, l’urbanisation n’est pas limitée à l’expansion de très grandes métropoles comme Mumbai, Delhi ou Bengaluru. Les villes de moins de 100 000 habitants regroupent quarante pour cent des urbains. Souvent oubliées, invisibles et négligées par les politiques urbaines, ces petites villes dont le nombre n’a de cesse de croître au fur et à mesure que les localités se diversifient constituent une caractéristique majeure de la transition territoriale qui s’opère en Inde. Nous proposons la notion d’urbanisation subalterne pour désigner ce caractère in situ des mutations urbaines dans un contexte de faiblesse structurelle des migrations résidentielles vers les grandes villes. Fondée sur une synthèse d’une vingtaine d’études de ces petites localités, nous mettons en évidence différentes configurations urbaines que l’on peut synthétiser en 4 types : les villes sous influences, les micropolis, les bourgs marchands et les localités ordinaires. Les échanges entre ces localités comme les liens avec leur arrière-pays ainsi que leur insertion dans des chaînes de valeur globalisées composent de nouveaux territoires urbains étendus. Ces halos urbains structurent une urbanisation horizontale qui doit être envisagée comme une opportunité dans le contexte grandissant d’incertitude générale et de saturation des métropoles.
Des bienfaits de l’usage des « monographies comparées ». Retour sur une comparaison transatlantique
Authors: Briche Henri
Published: June 2021

Tiraillée entre singularité des cas et montée en généralité, la comparaison demeure très souvent prisonnière des limites de chacune de ces approches. Depuis peu, une technique hybride s’est développée dans la recherche urbaine afin d’apporter des éléments de réponse à cette tension. Au croisement des méthodes hypothético-déductives et inductives, les « monographies comparées » identifient les variables à comparer sans pour autant évincer la complexité de chacun des terrains étudiés. Appliquée durant un travail de thèse comparant les politiques de redéveloppement urbain et ses effets sur les minorités ethniques dans deux villes en décroissance – Detroit (USA) et Saint-Étienne (France) – la technique des « monographies comparées » a été salutaire pour dépasser trois écueils de la comparaison transatlantique. L’exceptionnalité des villes américaines, l’absence des pouvoirs publics dans le redéveloppement urbain américain et l’invisibilité de la variable ethnique en France sont ainsi battus en brèche. À l’aune de ces apports, les « monographies comparées » s’inscrivent pleinement dans la dynamique de porosité des recherches urbaines contemporaines.
Le dessin, la grossesse et l’enfant à naître
Authors: Perelman Olga , Riazuelo Hélène , Carvalho Eduarda , Missonnier Sylvain
Published: June 2021

Partant de trois travaux de recherche en psychologie clinique psychanalytique et développementale ayant porté sur les représentations du corps de la femme enceinte et du bébé à naître au cours de la grossesse, nous cherchons à souligner l’intérêt de proposer le dessin au cours d’entretiens en période périnatale comme support à l’élaboration psychique. Notre objectif est ainsi d’exposer ces trois recherches et les contextes cliniques dans lesquels cette méthodologie a été exploitée (populations de femmes enceintes primipares et multipares, données quantitatives et qualitatives). L’analyse des dessins se révèle pertinente lors d’entretiens de recherche mais également en matière de prévention psychopathologique périnatale. La proposition de dessiner a sollicité un matériel associatif riche accompagnant le travail de représentation parentale maternelle.
De la difficulté scolaire au handicap, un nouveau mode d’exclusion ? À propos du parcours de trois enfants
Authors: Laure Frédéric , Chagnon Jean-Yves
Published: June 2021

L’article propose une étude critique du phénomène de médicalisation voire « handicapisation » de la difficulté scolaire. Chaque année, il est en effet constaté une augmentation considérable du nombre d’enfants en difficultés dans l’école pour apprendre ou devenir élèves qui basculent vers le champ du handicap. L’hypothèse soutenue ici est que cette inflation numérique révèle des défaillances dans le diagnostic et la prise en charge de la difficulté scolaire, défaillances qui font encourir le risque d’un basculement abusif de la difficulté vers le handicap. Après être revenus sur les mutations anthropologiques qui composent un terreau fertile à un tel phénomène, nous interrogeons les différentes politiques publiques et leurs instances qui ont conduit à ce basculement du pédagogique vers le médical, plus spécifiquement neurologique. Nous montrons comment la loi de 2005 pour l’égalité des droits et des chances a été utilisée et déviée, sur le terrain, de son principe fondateur pour compenser et soulager les pédagogues de choix politiques et idéologiques dans la prise en charge de la difficulté scolaire, notamment l’affaiblissement des RASED. Trois situations cliniques sont étudiées : elles nous permettent de comprendre du dedans ce qui se joue entre parents, enseignants, éducateurs et soignants dans cette absence de mise en sens et cette urgence de solutions rapides. La constitution d’un dossier de demande de reconnaissance de handicap à destination de la Maison Départementale des Personnes Handicapées (MDPH) s’effectue sans qu’un véritable travail de réflexion collective, notamment sur les plans pédagogique, psychopédagogique et psychopathologique, ait pu avoir lieu, et ce, malgré une surabondance de bilans. Nous montrons comment les « équipes éducatives », qui préexistent à la constitution des dossiers à destination de la MDPH, peinent à être des lieux où l’élève se pense dans son environnement au sens large et, où, de plus en plus, la logique de la compensation des manques individuels domine sur celle de l’accessibilité aux savoirs.
Ethics in Public and Community Psychiatry
Authors: Freudenreich Oliver , Kontos Nicholas , Querques John
Published: June 2021

Public and community psychiatrists who care for patients with serious mental illnesses regularly face ethical challenges. This article summarizes key ethical considerations in the care of a population that can be difficult to engage and may reject treatment, sometimes necessitating coercive care. The digital revolution in medicine, with its promises and perils and accelerated by coronavirus disease 2019 (COVID-19), has added ethical complexity regarding privacy and access to care. Shared decision-making, a process to resolve ethical dilemmas, and commitments to professionalism and reflective practice are emphasized as three ways to practice ethically in public and community psychiatrists' daily work. Additionally, COVID-19 has highlighted that engagement in social justice is a critical element of ethical practice for physicians today.

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Psychiatr Ann
. 2021;51(6):272–277.]
Individual- and System-Level Solutions for Promoting Integrated Medical Care for People with Serious Mental Illness in Public and Community Psychiatry
Authors: Schnitzer Kristina , Cather Corinne
Published: June 2021

People with serious mental illness (SMI) face a striking mortality disparity of 10 to 28 years as compared to the general population, largely attributable to chronic and preventable disease. In this article, we highlight a few practical steps that individual psychiatrists can take to implement recommended screening, monitoring, and treatment strategies for metabolic risk parameters as well as guidance for promoting tobacco cessation. We introduce several selected multicomponent behavioral interventions with demonstrated effectiveness for obesity and diabetes in this population. The article closes with a brief overview of organizational models for collaborative care and reverse integrated care, which aim to improve health outcomes for those with SMI through a team-based approach to medical and psychiatric care—such models may be considered by service providers at the institutional level.

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Psychiatr Ann
. 2021;51(6):261–265.]
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Presentation, Diagnosis, and Management
Authors: Hur Moon Hee
Published: June 2021

Pediatric demyelinating syndromes are a spectrum of diseases affecting the central nervous system. In the past decade, major advances have been made in this field, including the discovery of antibody-based biomarkers and treatment guidelines for specific syndromes. When myelin oligodendrocyte glycoprotein (MOG) antibodies were first discovered, they were thought to be a biomarker for multiple sclerosis (MS). However, further research has shown that MOG positivity during the first episode of a pediatric demyelinating syndrome is a predictor of a course that is distinct to MS. This article discusses the clinical manifestations of MOG antibody associated disease and key distinguishing features in the investigation, treatment, and prognosis between MOG and other demyelinating diseases.

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Pediatr Ann
. 2021;50(6):e254–e258.]
Stability results of a singular local interaction elastic/viscoelastic coupled wave equations with time delay
Authors: Akil Mohammad , Badawi Haidar , Wehbe Ali
Published: June 2021

The purpose of this paper is to investigate the stabilization of a locally coupled wave equations with non smooth localized viscoelastic damping of Kelvin-Voigt type and localized time delay. Using a general criteria of Arendt-Batty, we show the strong stability of our system in the absence of the compactness of the resolvent. Finally, using frequency domain approach combined with the multiplier method, we prove a polynomial energy decay rate of order \begin{document}$ t^{-1} $\end{document}.
Convergence of maximum likelihood supertree reconstruction
Authors: Dinh Vu ,   Department of Mathematical Sciences, University of Delaware, Newark, Delaware, USA, Ho Lam Si Tung ,   Department of Mathematics and Statistics, Dalhousie University, Halifax, Nova Scotia, Canada
Published: June 2021

Supertree methods are tree reconstruction techniques that combine several smaller gene trees (possibly on different sets of species) to build a larger species tree. The question of interest is whether the reconstructed supertree converges to the true species tree as the number of gene trees increases (that is, the consistency of supertree methods). In this paper, we are particularly interested in the convergence rate of the maximum likelihood supertree. Previous studies on the maximum likelihood supertree approach often formulate the question of interest as a discrete problem and focus on reconstructing the correct topology of the species tree. Aiming to reconstruct both the topology and the branch lengths of the species tree, we propose an analytic approach for analyzing the convergence of the maximum likelihood supertree method. Specifically, we consider each tree as one point of a metric space and prove that the distance between the maximum likelihood supertree and the species tree converges to zero at a polynomial rate under some mild conditions. We further verify these conditions for the popular exponential error model of gene trees.
Modeling the Critical Success Factors for Business Intelligence Implementation
Authors: Chaudhry Kanika , Dhingra Sanjay
Published: June 2021

Business intelligence (BI) helps organizations to make better and quicker decisions. The primary requirement, as per previous studies, for any successful BI implementation in an organization and its' stakeholders, is to understand and pay heed to the vital issues and factors governing it. The objective of this study is, thus, to analyze the various critical success factors (CSF’s) for Business Intelligence Implementation, in context to the Indian sub-continent. In this qualitative study, the CSF’s for BI implementation are classified, through the review of the literature and to identify the relationship among the CSF's, Interpretive Structural Modeling (ISM) is applied along with MICMAC classification method. The ISM approach's outcome shows that management support and business goal alignment are the most significant driving factors for implementing BI. These findings may help recognize the crucial facts that affect the firms adopting BI in India and give some insights for other countries
COVID-19 Information Seeking and Utilization Among Women in Warri Metropolis, Delta State, Nigeria
Authors: Adomi Esharenana E. , Oyovwe-Tinuoye Gloria O.
Published: June 2021

The study is intended to explore COVID-19 information seeking and utilization among women in Warri Metropolis, Delta State, Nigeria. Descriptive survey research design was adopted using a self-constructed questionnaire to collect data. Data were analyzed using simple percentages. Findings revealed that a majority of the women need information on COVID-19 preventive measures, followed by causes of the pandemic; Internet is the source of COVID-19 information used by the highest number of respondents, followed by television and social media; a majority of them consider the authority of the source of the information on coronavirus followed by usefulness of the information; a majority access COVID-19 information to enable them identify symptoms of the disease followed by protection against COVID-19 infection while concern for reliability of much of the available information on the pandemic was a major barrier to their utilization of COVID-19 information. It is recommended that effort should be made by government to get mobile network operators to reduce network tariff.
Direct and Indirect Effects of ICT Infrastructure, Skills, and Use on Entrepreneurship
Authors: Shrivastava Utkarsh , Ofstein Laurel , Golhar Damodar
Published: June 2021

The information and communication technology (ICT) enabling infrastructure, requisite skills, and subsequent usage in the country could facilitate ease of doing business (EDB) and support the heterogeneous distribution of resources for new businesses to flourish and remain competitive. However, from a policy perspective, the pathways through which ICT impacts entrepreneurial activities in a country are not clearly understood. In this study, we empirically investigate the direct and indirect (via EDB) effect of ICT infrastructure, skills, and use (at business, government, and individual level) in influencing entrepreneurial activity in a country. The results show that the citizens' ICT skills and ICT use, directly and indirectly, impact entrepreneurial initiatives in a country. In contrast, ICT infrastructure and use by the government only have an indirect impact on them. The study's findings should help guide national initiatives for promoting the creation of new businesses in a country.
Unsettled Issues Regarding Communication of Automated Vehicles with Other Road Users
Authors:   Silicon Valley Mobility, Beiker Sven
Published: June 2021

The focus of this SAE EDGE™ Research Report is to address a topic overlooked by many who choose to view automated driving systems and AVs from a “10,000-foot” perspective: how automated vehicles (AVs) will actually communicate with other road users. Conventional (human-driven) vehicles, bicyclists, and pedestrians already have a functioning system of understating each other while on the move. Adding automated vehicles to the mix requires assessing the spectrum of existing modes of communication – both implicit and explicit, biological and technological, and how they will interact with each other in the real world. The impending deployment of AVs represents a major shift in the traditional approach to ground transportation; its effects will inevitably be felt by parties directly involved with the vehicle manufacturing and use and those that play roles in the mobility ecosystem (e.g., aftermarket and maintenance industries, infrastructure and planning organizations, automotive insurance providers, marketers, telecommunication companies). Unsettled Issues Regarding Communication of Automated Vehicles with Other Road Users brings together the multiple scenarios we are likely to see in a future not too far away and how they are likely to play out in practical ways.
Unsettled Issues on Human-Robot Collaboration and Automation in Aerospace Manufacturing
Authors:   Cranfield University, Webb Philip , Fletcher Sarah ,   Cranfield University
Published: June 2021

This SAE EDGE™ Research Report builds a comprehensive picture of the current state-of-the-art of human-robot applications, identifying key issues to unlock the technology’s potential. It brings together views of recognized thought leaders to understand and deconstruct the myths and realities of human- robot collaboration, and how it could eventually have the impact envisaged by many. Current thinking suggests that the emerging technology of human-robot collaboration provides an ideal solution, combining the flexibility and skill of human operators with the precision, repeatability, and reliability of robots. Yet, the topic tends to generate intense reactions ranging from a “brave new future” for aircraft manufacturing and assembly, to workers living in fear of a robot invasion and lost jobs. It is widely acknowledged that the application of robotics and automation in aerospace manufacturing is significantly lower than might be expected. Reasons include product variability, size, design philosophy, and relatively low volumes. Also, the occasional reticence due to a history of past false starts plays a role too. Unsettled Issues on Human-Robot Collaboration and Automation in Aerospace Manufacturing goes deep into the core questions that really matter so the necessary step changes can move the industry forward.
Unsettled Topics Concerning Human and Autonomous Vehicle Interaction
Authors:   Raztech Research Institute, Razdan Rahul
Published: June 2021

This report examines the current interaction points between humans and autonomous systems, with a particular focus on advanced driver assistance systems (ADAS), the requirements for human-machine interfaces as imposed by human perception, and finally, the progress being made to close the gap. Autonomous technology has the potential to benefit personal transportation, last-mile delivery, logistics, and many other mobility applications enormously. In many of these applications, the mobility infrastructure is a shared resource in which all the players must cooperate. In fact, the driving task has been described as a “tango” where we—as humans—cooperate naturally to enable a robust transportation system. Can autonomous systems participate in this tango? Does that even make sense? And if so, how do we make it happen?