bluuebunny/crossref_metadata_2025 huggingface dataset:
Establishing and Boosting Communication in The European Reference Network For Rare Neurological Diseases (ERN-RND): The Impact of Offering Free Educational Webinars
Authors: Brunelle-Praschberger Alicia , Post Annemarie E.M. , Hermanns Sanja , Graessner Holm
Published: October 2021

Background: Since it first started operating in 2017, the European Reference Network for Rare Neurological Diseases (ERN-RND) implemented a multi-channel communication strategy to effectively reach its target audience: healthcare professionals, patients, researchers, industry representatives and the general public. It first created a website containing useful and up to date information followed by social media accounts. We compared the analytical data collected about the ERN-RND website and social media channels (Twitter, Facebook, YouTube) during two periods: October 2018 to September 2019 and the year after the ERN-RND free educational webinars were launched, from October 2019 to September 2020. This allowed us to quantify the impact of offering a tangible product (webinars) on the communication strategy. Results: The analytical data obtained from October 2018 to September 2019 and from October 2019 to September 2020 clearly shows a significant increase in traffic and followers since the launch of the ERN-RND webinars in November 2019. We also created a communication survey which was disseminated between February and June 2021. We collected responses from 61 people: 38 healthcare professionals, 11 scientists, 10 patients (advocates), 2 industry representatives, 1 patient association, 1 charity representative, 1 resident and 1 master student. Most respondents answered ”webinars” as the number one reason when asked about which content they look for on the ERN-RND website. Conclusions: Offering a tangible product - such as the webinars presented in this report - to a specific target group (healthcare professionals) supported our communication strategy by driving traffic to ERN-RND communication channels. It has also successfully tackled ERN-RND’s general aim: by enabling the flow of knowledge on rare neurological and movement disorders reach the medical community in hospitals treating patients with these rare and complex conditions, patients ultimately benefit from improved and faster diagnosis, care, and treatment. We aim to set up similar strategies to effectively reach other or the same target groups. For healthcare professionals, organising eConsultations via the Clinical Patient Management System (CPMS) or disseminating standards of care such as diagnostic and therapeutic algorithms as well as clinical practice guidelines might offer potential. For the patient community, organising customised and multilingual webinars could also work.
External Debt Burden and Infrastructural Development Nexus in Nigeria: An ARDL Approach (1981-2020)
Authors: Onwuka Chinonye Emmanuel
Published: October 2021

This study focused on external debt burden and infrastructural development nexus in Nigeria using data spanning between the periods 1981 to 2020 by employing the use of Autoregressive Distributed Lag Model (ARDL) and granger causality test as the major statistical techniques of analysis. From the findings, the coefficient of error correction term shows that about 70 percent of the discrepancy between the actual and the long run or equilibrium value of infrastructural development is corrected or eliminated each year. The coefficient of determination (R2) is 0.680 which shows that about 68 percent variations in the infrastructural development were explained by the independent variables. The Augmented Dickey Fuller (ADF) unit root test shows that all variables were stationary at first difference. The results for the Bounds test reveal that there is a long run relationship among the variables. This is because the F-statistics value (5.194) is greater than upper Bounds critical values at 5% level of significant. The ARDL results show that external debt, domestic debt and inflation rate have a negative impact on infrastructural development in the long run while exchange rate and interest rate has a positive effect on infrastructural development in the long run. Also, domestic debt and exchange rate were found to have a significant impact on infrastructural development while external debt, inflation rate and interest rate were found to be insignificant in the long run. Furthermore, the granger causality test results indicate while there is no causality between external debt and infrastructural development, there seems to be a unidirectional causality between domestic debt and infrastructural growth in Nigeria. The study concludes that federal government of the country should cut down excessive borrowings and that the existing ones are invested in projects that would eventually generate enough returns to defray such debts accordingly. Also, an adoption of policy framework that will ensure macroeconomic stability such as price stability, job creation, increased output, political stability, etc. becomes fundamental in getting rid of heavy reliance on external debt in the country.
Investigating Molecular Mechanisms of Insecticide Resistance in the Eastern Democratic Republic of the Congo
Authors: Bandibabone Janvier , McLoughlin Charles , N'Do Sévérin , Bantuzeko Chimanuka , Byabushi Vital , Jeanberckmans Muhigwa , Guardiola Maite , Zawadi Bertin , Diabaté Abdoulaye , Prudhomme Jorian , Walker Thomas , Messenger Louisa Alexandra
Published: October 2021

BackgroundMalaria vector control in the Democratic Republic of the Congo is plagued by several major challenges, including inadequate infrastructure, lack of access to health care systems and preventative measures, and more recently the widespread emergence of insecticide resistance among Anopheles mosquitoes. Across 26 provinces, insecticide resistance has been reported from multiple sentinel sites. However, to date, investigation of molecular resistance mechanisms among Anopheles vector populations in DRC has been more limited.MethodsAdult Anopheles gambiae s.l. and Anopheles funestus s.l. were collected from two sites in Sud-Kivu province and one site in Haut-Uélé province and PCR-screened for the presence of 11 resistance mutations, to provide additional information on frequency of resistance mechanisms in the eastern DRC, and to critically evaluate the utility of these markers for prospective country-wide resistance monitoring. ResultsL1014F-kdr and L1014S-kdr were present in 75.9% and 56.7% of An. gambiae s.l. screened, respectively, with some individuals harbouring both resistant alleles. Across the three study sites, L43F-CYP4J5 allele frequency ranged from 0.42-0.52, with evidence for ongoing selection. G119S-ace1 was also identified in all sites but at lower levels. A triple mutant haplotype (comprising the point mutation CYP6P4-I236M, the insertion of a partial Zanzibar-like transposable element and duplication of CYP6AA1) was present at high frequencies. In An. funestus s.l. cis-regulatory polymorphisms in CYP6P9a and CYP6P9b were detected, with allele frequencies ranging from 0.82-0.98 and 0.65-0.83, respectively. ConclusionsThis study screened the most up-to-date panel of DNA-based resistance markers in An. gambiae s.l. and An. funestus s.l. from the eastern DRC, where resistance data is lacking. We identified several new candidate markers (CYP4J5, G119S-ace1, the triple mutant, CYP6P9a and CYP6P9b), which are diagnostic of resistance to major insecticide classes, and warrant future, larger-scale monitoring in the DRC to inform vector control decisions by the National Malaria Control Programme.
Determinants of Male Involvement in Family Planning Services in Abia State, Southeast Nigeria
Authors: Amuzie Chidinma Ihuoma , Nwamoh Uche Ngozi , Ukegbu Andy , Umeokonkwo Chukwuma David , Azuogu Benedict Ndubueze , Agbo Ugonma Okpechi , Balogun Muhammad Shakir
Published: October 2021

Background: Male involvement in family planning (FP) remains low in male-dominant communities. Family planning contributes to the regulation of fertility and population growth in Nigeria. Increasing male involvement in family planning services is crucial in reducing maternal morbidity and mortality in patriarchal societies such as Nigeria. This study identified the determinants of male involvement in family planning services in Abia State, Nigeria. Methods: This was a cross-sectional study conducted in twelve communities of Abia State, Nigeria. A total of 588 married men who met the eligibility criteria were recruited using a multistage sampling technique. An interviewer-administered semi-structured questionnaire was used to collect data on the variables. Univariate, bivariate and multivariate analysis was done. The level of significance was set at 5%. Results: The overall level of active male involvement in family planning services was 55.1% (95% CI:51.0%- 59.2%). The mean age of the respondents was 42.4±8.0 years. Access to television (aOR= 1.58, 95% CI: 1.05-2.39), spouse employment status (aOR= 2.02, 95% CI: 1.33-2.06), shared decision-making (aOR= 1.66, 95% CI: 1.05-2.62), and accompanying spouse to the FP clinic (aOR= 3.15, 95% CI: 2.16-4.62) were all predictors of active male involvement.Conclusion: Active involvement of men in family planning services was moderate. This was predicted by access to television, employment status of spouse, shared decision-making, and accompanying spouse to the FP clinic. There is a need to focus on the identified factors in order to further improve the active involvement of men in FP services.
Experimental Investigation On Machining Performance During Orbital Drilling of CFRP
Authors: Kong Linghao , Gao Dong , Lu Yong , Zhang Pengfei
Published: October 2021

As the most promising CFRP hole making method, orbital drilling is widely concerned. This paper aims to understand the influence of the cutting parameters, tool diameters and ratio between milling and drilling (Rm&d) on thrust force, cutting temperature, tool wear and machining quality in CFRP orbital drilling. The effects of cutting parameters on thrust force and cutting temperature were studied by orthogonal experiments, and experiments were performed to investigate the variations of tool diameters, ratio between drilling and milling on thrust force, cutting temperature, tool wear and machining quality. The experimental results show that the tangential feed rate has no apparent effects on thrust force, but it appreciably impacts on the cutting temperature. The selection of tool diameter and the Rm&d has specific influence on tool wear, machining quality and cutting temperature. The result is helpful for selecting cutting parameters and tool diameters for high quality holes machining in CFRP orbital drilling.
A Robust Fast Bridging Algorithm for Laser Cutting
Authors: Hu Qirui , Lin Zhiwei , Fu Jianzhong
Published: October 2021

Bridging the different parts together is considered a simple but effective strategy to reduce the number of piercing operations during laser cutting. However, fast bridging is never an easy task. In this paper, we present a near-linear bridging algorithm for the input parts with the shortest total bridge length. At first, the input part contours are discretized into a point cloud, then the point cloud is triangulated with the Delaunay standard. The shortest line segments between any two adjacent parts are found in the triangles connecting the two parts. These segments are finally extended into bridges. To solve the problem of the damages to the contour characteristics caused by the bridges, some restrictions are set on the screening of the discrete point cloud and the Delaunay triangles. This algorithm not only ensures the minimum total distance of all bridges, but also avoids the problem of generating bridge loops. Computational experiments show that the proposed bridging algorithm is much faster than that in existing commercial software. The feasibility and superiority of the algorithm are verified by actual lasering cutting experiments.
Cryptoanalysis on a Cloud-Centric Internet-of-Medical-Things-Enabled Smart Healthcare System
Authors: Chang Jinyong , Ren Qiaochuan , Zhang Anling
Published: October 2021

The interconnecting of the biomedical sensors (in healthcare system) with cloud for the internet-of-medical-things (IoMT) technology has great potential to ameliorate people's living conditions. The privacy-preserving of personal health information (PHI) and the mutual authentication between the sensors and other entities are two main factors that affect the further applications of cloud-centric IoMT technology. In the recent work [IEEE IoT Journal, vol. 7(10), 10650-10659, 2020], Kumar and Chand applied identity-based aggregate signcryption scheme to the smart healthcare system (KC-system, for short), which provides privacy-preserving of PHI and the mutual authentication function, simultaneously. However, in this paper, we carefully analyze the security of KCsystem and find out that the critical authentication keys of entities can be easily recovered from their communication contents. In other words, the mutual authentication function of KC-system can be easily broken. Moreover, the recovering of the keys will lead to the tedious processes, including obtaining partial private key (from network manager) and requesting for key-protection (from key-protection servers), become completely useless. Finally, we remark that it seems to be hard to remedy the current KC-system so that it is immune to our attack.
Influence of a Turbulent Jet Engine Exhaust on Laguerre-Gaussian Correlated Shell-Model Beams
Authors: Nabil Hassan , Balhamri Adil A. , Belafhal Abdelmajid
Published: October 2021

In this paper, we investigated the influence of a turbulence jet engine exhaust on Laguerre-Gaussian correlated shell-model beams (LGSMBs). The analytical formulae of the cross-spectral density function as well as the beam width are derived based on the Huygens-Fresnel diffraction principle and the second-order moments of the Wigner distribution function, respectively. From our main results, the spectral density, the degree of coherence and beam width of a LGSMB are analyzed numerically. It is found that for high source coherence width, the spectral density changes gradually its profiles from circular to elliptical shape at short propagation distance, then the beam transforms into a well like Gaussian at long propagation distance. Although, at very short propagation distance, the beam becomes an elliptical dark hollow if the source coherence is very lower. Also, the numerical results show that the LGSMB spreads more rapidly than the GSMB in the same conditions.
A new low complexity bus travel time estimator for fleet management system
Authors: Alizade Emad , Hendessi Ali , Hendessi Faramarz , Hashemi Massoud Reza
Published: October 2021

Improving the experience of using the public transportation system can be done by estimating the arrival time of the bus and notifying the passengers. Consequently, the accuracy of the estimation affects this experience. As the number of buses, stations, and service areas increases, so does the data collected in the cloud, making travel time estimation-related data processing more challenging. Despite this challenge, a distributed method for estimating the arrival time of the bus is considered in this paper. Also, we present a way to decentralize data processing and distribute it on each bus. Besides, using the Kalman filter and updating the estimated values at short intervals improves the estimation error. Examination of the degree of complexity shows that the proposed method has significantly reduced the complexity in the cloud, which makes the proposed method can be implemented in metropolitan areas. The results of implementation on a dataset, show that the proposed method has a good performance in terms of mean square error and root mean square.
Adaptive Machining Scheme for Multi-Hole Part with Multi-Position Accuracy Requirements
Authors: Sun Zhen , Feng Pingfa , Zeng Long , Zhang Shaoqiu , Cheng Xi
Published: October 2021

The machining of multi-hole parts often has complex correlated position accuracy requirements. When some position accuracies do not meet the requirements, several hole axes need to be adjusted. Previous methods usually correct all deviated axes to their theoretical locations. However, the correction workload is too large and inefficient. This paper proposes an efficient and adaptive hole position correction model for multi-hole part. First, the method establishes the topological relationship of the holes and faces on the part according to the position accuracy requirements of the multi-hole part. Then, the goal is to minimize the number of holes that need to be corrected. In this model, the parallelism of holes, perpendicularity, and other constraints are considered. The simulation and experimental results show that the use of this model can effectively reduce the number of holes that need to be corrected during the compensation of the position error between holes. It improves the efficiency in the subsequent compensation process significantly.
Beta3-Adrenergic Receptor (β3-AR) Modulation Prior to and / or at the end of Sustained Ischaemia and / or Early Reperfusion May Prove to be a Valuable Cardioprotective Strategy
Authors: Salie Ruduwaan , Marais Erna , Lochner Amanda
Published: October 2021

β3-AR activation contributes partly or may be solely responsible for ensuing cardiac damage in myocardial ischaemia or heart failure. This would largely depend on disease stage, severity, experimental model as well as drug specificities which should be considered when investigating β3-AR pharmacology for potential therapeutic applications. These conceptions largely contribute to the discrepancies of the subsequent role of β3-AR activation in the cardiovascular disease process. The β3-AR delivers a sustained intracellular signal because of its resistance to short term agonist promoted desensitization, making this receptor an ideal target for therapeutic intervention and in this manner protecting the heart from catecholamine overstimulation. The current communication highlights the importance of the cumulative effect of BRL (PerT) treatment, at the end stage of ischaemia as well as BRL (PostT) treatment, at the onset of reperfusion. This undoubtedly illustrate the significance of the end stage of ischaemia as well as the onset of reperfusion in the concept of ischaemia- reperfusion damage and the importance of the application of cardioprotective interventions at these time periods. Subsequently, if cardioprotective regimens are initiated during the late phase of ischaemia and continued into early reperfusion, it is likely that they will enhance protection, especially with longer durations of ischaemia.
A novel meta-heuristic optimization algorithm based on cell division: Cell Division Optimizer
Authors: Jain Sehej , Bharti Kusum Kumari
Published: October 2021

A novel meta-heuristic algorithm named as the Cell Division Optimizer (CDO) is proposed. The proposed algorithm is inspired by the reproduction methods at the cellular level, which is formulated by the well-known cell division process known as mitosis and meiosis. In the proposed model Meiosis and Mitosis govern the exploration and exploitation aspects of the optimization algorithm, respectively. In the proposed method, the solutions are updated in two phases to achieve the global optimum solution. The proposed algorithm can be easily adopted to solve the combinatorial optimization method. To evaluate the proposed method, 50 well-known benchmark test functions and also 2 classical engineering optimization problems including 1 mechanical engineering problem and 1 electrical engineering problem are employed. The results of the proposed method are compared with the latest versions of state-of-the-art algorithms like Particle Swarm Optimization, Cuckoo Search, Grey Wolf Optimizer, FruitFly Optimization, Whale Optimizer, Water-Wave Optimizer and recently proposed variants of top-performing algorithms like SHADE (success history-based adaptive differential evolution) and CMAES (Covariance matrix adaptation evolution strategy). Moreover, the convergence speed of the proposed algorithm is better than the considered competitive methods in most cases.
Ruthenian Devotional Songs As Collectors’ Items?
Authors: Stern Dieter
Published: October 2021

At the turn of the sixteenth and the seventeenth centuries, syllabic devotional songs in Ruthenian (RDS) make their first appearance as occasional appendices or notes in the margins of manuscripts serving quite divergent functions (triodia, evangelia and the like). The first systematic collections of RDS were compiled abroad by Ruthenian monks having left Ukraine for monasteries around Moscow from the 1660s onwards. It required several more decades, till the beginning of the eighteenth century, before these songs were also being systematically collected in song manuscripts throughout the Ruthenian lands themselves. The article argues against established views to the effect that this documentary gap was due to a massive loss of seventeenth-century Ruthenian song manuscripts. It should rather be taken at face value as an indication that some perceptual change with respect to devotional songs is likely to have taken place among Ruthenian literate classes at the beginning of the eighteenth century. It is argued that the rise of Ruthenian song manuscripts marks the beginning of a collecting culture, which treats devotional songs as a cherished and coveted collectable, where heretofore no particular value seems to have been accorded to these songs. The article explores the social profiles of song collectors and the individual makeup of song collections to offer a hypothetical outline of this emerging collecting culture, addressing issues of modes of exchange, methods of collecting and compiling, the specific relationship between collector and collectable, with a view to arguing for a highly individualized and intimate culture between private devotion and incipient object-oriented consumerism.
The Role of English Proficiency in the Adaptation of Ukrainian Immigrant Children and Youth in Saskatchewan, Canada
Authors: Bryzh Kateryna , Makarova Veronika
Published: October 2021

This article reports the results of a small-scale study examining the role of English language proficiency in the adaptation of Ukrainian immigrant children and youth to life in Saskatchewan, Canada. The main objective of the study was to describe issues related to English as a Second Language (ESL) proficiency as they are perceived by Ukrainian children and youth and by their parents. The second objective of the study was to explore the following factors in the adaptation process: age, gender, duration of stay in Canada, age upon arrival in Canada, ESL class attendance, school type (English as the language of instruction or bilingual), and level of English proficiency. A total of 60 participants (30 children/youth and 30 parents) took part in the study. The methodology (mixed quantitative/qualitative) involved semi-structured interviews with the children/youth participants, an evaluation of their ESL proficiency, and a questionnaire survey of parents’ views on ESL-related adaptation difficulties experienced by children/youth. The results demonstrated that most Ukrainian immigrant children/youth reported that limited English proficiency was a major problem for them when they moved to Canada. The results of the study suggest that the difficulties experienced by a child who immigrates to Canada depend on the child’s ESL speaking proficiency, general ESL proficiency, duration of stay in Canada, and age upon arrival in Canada.
Non-compliant Reading and Annotating in the Ruthenian Reformation: Cyril of Jerusalem’s Mystagogical Catechisms from Szymon Budny’s Library
Authors: Ivanova Maria
Published: October 2021

While the works of the Antitrinitarian thinker and religious leader Szymon Budny (ca. 1530-93) have been the subject of extensive scholarly research, his library, marginalia, and reading practices have been significantly less examined. Following the discovery of a copy of Cyril of Jerusalem’s Mystagogical Catechisms (Vienna, 1560) belonging to Budny, I analyze Budny’s notes and comments regarding the Latin translation of Cyril’s text as a case study of Budny’s attempt to recover the Church Father from the Catholic post-Tridentine agenda and his own subsequent re-appropriation of Cyril for his radical non-adorantist program. By exploring Budny’s subversive reading and annotating strategies, I demonstrate Budny’s original contributions to the development of Antitrinitarian thought in Europe. I also illustrate how marginalia and paratexts reflect not only the history of the book in which they are found, but also how they throw light on religious and intellectual history.
The prevalence of posterior tongue tie in patients with transverse maxillary deficiency
Authors: Tome Wakako , Moon Won
Published: October 2021

Objectives

To investigate the prevalence of posterior tongue tie in orthodontic patients using numerical and clinical assessment methods in order to identify an association between posterior tongue tie and transverse maxillary deficiency.

Materials and methods

Seventy-nine participants from an orthodontic clinic were divided into two groups. The first group of 44 patients exhibited a skeletally narrow maxilla and required maxillary skeletal expansion (MSE group) and 35 patients without a transverse discrepancy comprised a control group. Posterior tongue tie was examined by the Kotlow tongue tie classification, tongue range of motion ratio (TRMR) and via a clinical assessment. The prevalence of posterior tongue tie was compared between the two groups.

Results

There was no significant difference in the level of the Kotlow classification grade between the two groups (p > 0.05) and the overall majority was diagnosed as normal. However, a higher proportion of posterior tongue tie was found in the MSE group than in the control group by clinical assessment (MSE group, 72.7%; control group, 42.9%; p = 0.005). The proportion of TRMR grade 2 was also higher in the MSE group than in the control group (p = 0.001). Of the subjects diagnosed with posterior tongue tie by clinical findings, approximately 94% showed TRMR grades 2 or 3.

Conclusions

A clinical assessment of posterior tongue tie was found to be simple and accurate, whereas a numerical assessment alone provided diagnostic difficulty. Considering the high prevalence of observed posterior tongue tie in the MSE group, there was a significant association between posterior tongue tie and transverse maxillary deficiency.
HP-PdF2-type FeCl2 as a potential Cl-carrier in the deep Earth
Authors: Yuan Hongsheng , Man Lianjie , Kim Duck Young , Popov Dmitry , Meng Yue , Greenberg Eran , Prakapenka Vitali , Zhang Li
Published: October 2021

We report for the first time the formation of a HP-PdF2-type FeCl2 phase (space group Pa3), through high pressure-temperature (P-T) reactions in the hydrous systems (Mg0.6Fe0.4)SiO3–H2O–NaCl and FeO2H–NaCl in a laser-heated diamond-anvil cell up to 108 GPa and 2000 K. Applying single-crystal X-ray diffraction (XRD) analysis to individual submicrometer-sized grains, we have successfully determined the crystal structure of the as-synthesized FeCl2 phase, in agreement with our theoretical structure search results. In situ high P-T XRD data revealed the substitution of Cl for OH(O) in such a cubic Pa3 structure, demonstrating that this topology is a potential host for both H and Cl in the deep Earth. The chemical analysis of the recovered sample showed that the post-perovskite phase contains considerable amounts of Na2O and Fe2O3. The coexistence of the cubic FeCl2 phase and post-perovskite suggests that the lowermost mantle could be a potential reservoir of Cl. The possible presence of volatiles such as H and Cl in the deep lower mantle would impact the composition and iron valence state of the post-perovskite phase.
Designing Wayang Kulit Purwa with Gatotkaca as the Character in Game
Authors: Bonafix Nunnun
Published: October 2021

Young generation nowadays has lack of knowledge on the culture of shadow puppet (wayang kulit) which is a heritage that has a high value of art and philosophy. This is caused by the impact of foreign cultures rapidly entering Indonesia. The rapid development of the information technology through internet & game has led to globalization that seems to be not limited to space and time. The speed of information and foreign cultures cannot be stopped. The culture of shadow puppet (wayang kulit) is getting eroded and is not much known by the modern society nowadays. This is an irony to a big nation which has a rich heritage, so it is our obligation as a citizen to maintain and preserve it. Based on the formulae of AIGA 2015 that defines (time + content + context) / time = experience design, the game of wayang kulit (shadow puppet) Gatotkaca put forbattled different experience to users in exploring the information and entertainment in those media. Having the spirit of moderate Postmodernism, the design plan called User Interface which combines the modern and classic traditional elements will encourage new experience to the users (Experience Design). The design recognizes times and trends, and it keeps changing as the development of the times. The design can be a pace setter to next individuals who are called to maintain and preserve national cultures, in general, and wayang kulit purwa, in particular, through digital media. The development in the modern era will not change the identity of shadow puppet (wayang kulit) culture since it has solid foundation.
Design of Gradual Contemporary Wayang Visual Character Indonesia For Sticker Chatting And Game Applications
Authors: Darmawan James , Harnoko Irwan
Published: October 2021

UNESCO international recognition in 2003 stated that wayang is one of Indonesia's cultural heritage, but the sense of belonging for wayang is still low among the nation's next generation of Indonesia. So at this time, both the government and the educators, still working to improve the regeneration of wayang knowledge and recognition for the young nation and the world, including through game application. In this study, the researchers created a contemporary virtual character of wayang, and will be inserted as a character sticker chatting and game application. This wayang virtual characters can be used as tools for reintroduction to young people around the world. This method will be conducted by researchers include depictions classification of facial expressions of emotion, collaborate with simplified visual approach, to obtain the corresponding visual characteristics of the wayang virtual characters. Researchers also used visual basic character as a prototype for contemporary form deformation, so it can be applied to the target games application and communication functions.
The Application of Gestalt and Design Principles on Visual Based Games for Children
Authors: Udin Noor
Published: October 2021

There are various visual games that we know, from puzzle, guess the picture, mix and match, and many more. Kids around the world play visual games because it is fun, imaginative, and stimulate their creativity. This research elaborates how visual games become more interested with the organization of visual elements through design principles and Gestalt theory. It proves that visualbased games are chosen by children and parents to develop their creativity and imagination.
Character Development Creativity in Unit Blocks for Visual Spatial Intellegence Improvement of Children with Special Needs
Authors: Tobroni Muhammad Imam
Published: October 2021

Autism is a neurodevelopmental disorder that is present from birth or early childhood. People with autism usually have impaired social interaction, difficulties in verbal and non- verbal communication, and repetitive behaviour. One of the forms of autism treatment is therapy. Vision therapy through toys that require concentration and creativity is able to treat autism as it won’t limit the imagination of children with the disorder. Toys usually have their own patterns and programs that tend to limit children’s creativity, imagination and visual and spatial intelligence. This can lead to children’s stress and lack of confidence. A character design on unit block toys is a form of vision therapy. It develops children’s visual and spatial creativity and intelligence. It also helps children to be independent and helps with their perception. Unit blocks consist of pieces of wooden blocks with different shapes and sizes that can form even bigger shapes, based on children’s imagination and ability to design a space or a building. Children’s visual and spatial intelligence help them visualize and notice shapes, colours, spaces, and designs of the unit blocks accurately, modify their surroundings based upon their perceptions, and recreate the aspects of their visual experiences. Playing Lego blocks will help develop the visual spatial intelligence of children with autism as it stimulates their ability to express ideas and to design a character the way they like.
Character Design in Games Analysis of Character Design Theory
Authors: Kuntjara Hagung , Almanfaluthi Betha
Published: October 2021

A character plays an important role in game sales on an application store. The first thing people notice when choosing a certain genre of a game on the application store is the character. Character appears in a game visual icon, alongside the name of the game and some stars representing the rating and the number of download. By looking at the game character, people will be able to tell the game genre and type, also the targeted users. Advanced technology might allow a game to develop better but analyzing the game character from its art and design aspect is also needed for it to be successful in the market. This paper will explain character design development and its art and design aspect using constructive method. The analysis can be used for better understanding on how games designers work and come up with the right idea of a game’s characters based on the game’s general idea.
How gaming, artificial intelligence and big data is changing education
Authors: Janine Teo Peihan
Published: October 2021

With 263 million children and youth out of school, there is a need for a highly scalable way to provide quality education to the underprivileged. Solve Education!(SE!)’s solution is combining an addictive game with the “Learning-by-Doing” Principle. Leveraging artificial intelligence and big data analysis, SE! explores the possibility of combining multi-user online strategy games with casual puzzle games to increase user retention rates, and in the process educating the users effectively over a longer period of time. Game mechanics are used to increase user retention by boosting motivation, while big data analysis allows SE! to understand the users’ in-game behavior and how they learn best. Artificial intelligence helps to deliver the right content to the user at the right time, optimizing the learning process, and enabling in-game adaption to the users’ learning needs
The Design and Development of Backend System for a Game Application
Authors: Tandey Louis Joshua
Published: October 2021

This paper is discussed a technical report regarding the backend system and the web application to manage the game and the API that the game client of Dishcover Indonesia will frequently request to a web application is one of the many ways that can be used to manage content that is saved on the backend for a system. An API is also a method. The author, part of a team development for a game, will attempt to provide a solution so that to easily maintain the content of the game and a method for the client to access with them.
Dishcover Indonesia: Android Cooking Game on Indonesian Cuisine
Authors: Widjaja Jeremy Jodi
Published: October 2021

The video game industry can be said to be one of the more modern undying industries that are ever growing and evolving. In Indonesia, there are several game development companies, however, there is currently no game that utilizes Indonesian cuisine as the main theme. It is also noted that there have been no recent cooking games that are unique nor a sequel. Currently, there is a gap in which consumers are not playing cooking games although they enjoy them. As a result, the author attempts to develop a game that can reach users’ expectations for a modern Android cooking game. Users were tested in two phases. Before the development, users were asked to rate their expectations of a cooking game and the current competition. After the development of the game, users were given the beta to test and rate their evaluation of the application. Based on the results of the two surveys, the game has achieved the results desired in the beginning of the project development.
Sesame Credit: Social Compliance Gamification in China
Authors: Reis Alessandro Vieira dos , Press Livia Topper
Published: October 2021

Sesame Creditis the gamified Chinese social credit. It aims at monitoring and controlling the behavior of more than a billion citizens until 2020. Basing itself on the distribution of rewards and punishments to individuals, upon scoring based on the compliance of the aforementioned citizens towards laws and government interests. The present study probes Sesame Credit from data collected from academic papers, Chinese government official documents, as well as media articles.An interpretative analysis is conducted based on the Octalysismethod of gamification and the motivational method known as the Self-Determination Theory. Residing as main conclusions: a) the efficiency of the Sesame Credit depends on extensive and continual monitoring of the population by the Chinese government; b) despite the coercive aspects, such gamification is observed to be as popular in China, due to a millenary tradition of people’s compliance to the social and those of authority obedience
Gamification Analysis for Motivation and Engagement Using Running Apps
Authors: Karlna Nia , Utoyo Arsa Widitiarsa , Saptaputra Emmanuel Himawan
Published: October 2021

Gamification is the application of game features, mainly elements of video games, in a context not related to the game in order to promote motivation and commitment to learning. The application of gamification in a pedagogical context provides some remedy for many people who feel alienated from traditional teaching methods. The use of gamification could provide a partial solution to the decrease in the motivation and commitment of the students that the user faces today. Specifically, the younger environment could benefit greatly from gamification not only for its enjoyment but also for a healthy life. This critical analysis of gamification literature wants to be part of a sequence on the effect of gamification on motivation and commitment. A methodology proposed in the study of the effects of gamification in motivation and commitment, as well as an empirical study, consists of a smartphone application that provides tracking and gamification elements. While the control arm consists of on an application designed identically only with the characteristics of tracking health information. The proposal will be made among young people who use applications on the day off from cars in Jakarta
Predicting the Effect of Violent Gameplaying to Violent Behavior Intention among Females using Tree Regression and AdaBoost Tree Regression
Authors: Maniah Maniah , Heryadi Yaya , Trisetyarso Agung , Abbas Bachtiar Saleh , Suparta Wayan , Gaol Ford Lumban
Published: October 2021

The issue on the effect of violent video game to aggressive behavior has gained wide interest from various communities. This paper presents some results of predicting quantitative measure of aggressive behavior from variables that measure violent video game playing. Experiment results showed that Decision Tree Regression (DTR) and Adaptive Boosting Tree Regression (AB-DTR) models predicted aggressive behavior intentions with high accuracy. For predicting Hostile variable: DTR’s training and testing RMSE (0.0, 0.0); AB-DTR’s training and testing RMSE (0.08, 1.08). For predicting Instru variable: DTR’s training and testing RMSE (0.0, 2.18); AB-DTR’s training and testing RMSE (0.0, 3.30) respectively.
Subliminal Paradigmatic on Designing Character in Games
Authors: Lubis Sulaiman Hakim , Zufri Tubagus
Published: October 2021

Not only rely on aesthetics alone, but character design also requires things that underlie decision making in the design process. The consideration may refer to the type of story, style and appearance that also refers to the form, which is part of the elements of design, but other than those designers must also be paid attention to other things that related with the problem that occurs when the game is played. Games will be played by players who in fact have experiences that will later be brought into the game and instead bring experience from within the game to the real world. This unconscious condition can also be used as a design consideration.
Re-Introducing Indonesian Traditional Games through an Interactive Multiplayer Table Game - Gobak Sodor
Authors: Pratalaharja Emanuel , Dirgantoro Bayu
Published: October 2021

Nowadays, many people have left their country’s traditions and cultures due to advancement of technologies. Indonesia is rich in diversity, also its traditional games that are an inseparable part of Indonesian culture that should be preserved. Traditional games are almost unknown and abandoned as children lack early knowledge because parents and teachers disregard their important role in teaching these games to children. Traditional games are not up- to-date and are replaced by modern and digital games. Moreover, children nowadays have less free time and are physically less active. Additionally, there are less fields to play nowadays. This project aims to re-introduce Indonesian traditional games by creating an interactive multiplayer table game about Gobak Sodor for Indonesian children from Generation Z, especially those around 9-12 years old. It also aims to overcome misconceptions that traditional games are not fun and increase interest on traditional games. The research methodology was done through literature studies, qualitative methods including site visits and in-depth interviews. Overall, the game can be a fun playing experience that can be played in limited space and time to re-introduce traditional games to children and encourage them to preserve Indonesian culture.
NUCLEARES EO SUBMARINO DE PROPULSÃO NUCLEAR: UMA PROPOSTA DE SIMULAÇÃO
Authors: de Andrade Flôr Cláudio Rogério , Scovino Gitahy Paula , Araújo Carlos Alexandre , Viana Souza Guimarães Victoria , Janick Vinícius
Published: October 2021

Atualmente, somente Estados Unidos, Rússia, Reino Unido, França, China e Índia possuem submarinos com propulsão nuclear. A situação singular do Brasil, por ser o primeiro paíssem armas nucleares a ter essa tecnologia e por, provavelmente, ser o primeiro país a colocar o combustível nuclear naval sob salvaguardas faz com que ele receba pressões para aderir ao Protocolo Adicional (PA) da Agência Internacional de Energia Atômica (AIEA). O artigo tem como apresentando uma apresentaçãode um projeto preliminar de uma simulação, como ferramenta de auxílio à tomada de decisão de alto nível, a fim de fazer frente às tendências e incertezas que podem interferir com o projeto do Submarino Convencional de Propulsão Nuclear Brasileiro (SCPN). Para tal propósito, são usadas como teoriasdos jogos, como de tomada de decisão, como de simulações / jogos de guerra e de análise. Foi verificado que, partindo da premissaque o SCPN será comissionado em 2029 é importante que o Brasil tome uma decisão em relação ao PA da AIEA Antes desse ano e que cenários prospectivos podem ser revistos ou reformulados anualmente ou a cada dois anos para Especificado, de modo a aumentar a probabilidade de se atender aos interesses brasileiros.
UM VENENO LETAL E UMA REFLEXÃO SOBRE A PROPRIEDADE INDUSTRIAL DE BENS PERIGOSOS: O CASO DA RICINA
Authors: Prado Dall'Agnol Rogéria , Francisco da Silva Gabriel
Published: October 2021

Este trabalho teve como objetivo o desenvolvimento de indicadores sobre patentes e / ou pedidos de patentes de produtos ou processos que envolvessem a ricina (Ricinus communis L.), uma toxina contida nas sementes de mamona e que é considerada um dos venenos mais letais do mundo. Foi realizado o mapeamento do quantitativo de todos os depósitos de pedidos de patentes relacionados a esta toxina, cruzando-se os dados obtidos com outras informações com o fim de obter novos indicadores que permitissem uma análise de exploração inicial a respeito da Propriedade Industrial e a proliferação da ricina como Arma Química. Foi realizadauma pesquisa exploratória com abordagens qualitativas e quantitativas em relação à coleta e análise de dados. Humilharescolhida para a recuperação dos dados de patentes foi a Derwent Innovations Index. Dos resultados obtidos foi possívelobservar que há aumento, principalmente nos últimos 10 anos, de pedidos de patentes que envolvem a medicina e que, com 4144 mil, a China detém o maior número de pedidos de patentes, seguida de 1243 mil pedidos da Organização Mundial de Propriedade Intelectual (OMPI), ficando os Estados Unidos em terceira posição com 705 pedidos e o Brasil em décima posição com 45 pedidos de patentes. Ficaevidente o crescimento nos números de pedidos de patentes envolvendo a ricina e que o grande número de informações contidas nos documentos de patentes bem como as concessões estes para exploração industrial podem colaborar para o uso da ricina como Arma de Destruição em Massa.
Correlation of the variations in prevalence of coronavirus disease 2019 and vitamin D receptor gene polymorphisms in cohorts from 26 countries
Authors: KARCIOĞLU Lütfiye
Published: October 2021

Aim: This study aimed to investigate the correlation between the rates of coronavirus disease 2019 (COVID-19) prevalence and mortality and the frequency of vitamin D receptor (VDR) gene polymorphisms at the loci rs7975232 (ApaI), rs1544410 (BsmI), rs2228570 (FokI), and rs731236 (TaqI) in cohorts from 26 countries.Methods: The study included the use of 26 countries where VDR gene polymorphisms at the loci rs731236 (TaqI), rs7975232 (ApaI), rs2228570 (FokI), and rs1544410 (BsmI) were determined and where the relevant frequencies of alleles in healthy populations were reported: Italy, China, Turkey, Japan, Mexico, Russia, India, Poland, Egypt, Czechia, Ethiopia, Saudi Arabia, Greece, the Netherlands, Korea, Spain, the United States, Pakistan, Nigeria, Lebanon, the Central African Republic, Finland, Iran, Tunisia, Brazil, and Croatia. The COVID-19 prevalence and mortality rates (per million population) reported for each country on 6 December 2020 were recorded.Results: A significant positive correlation was found between the frequency of AA genotype of rs7975232 and the COVID-19 prevalence (r=0.45, r2=0.20, p=0.02) and mortality (r=0.42, r2=0.17, p=0.03) rates. Twenty percent of the variability in prevalence and 17% of the variability in mortality could be explained by the frequency of AA genotype. Similarly, a significant positive correlation was found between the frequency of TT genotype of rs731236 and the COVID-19 prevalence (r=0.42, r2=0.17, p=0.03) rates. Seventeen percent of the variability in prevalence could be explained by the frequency of TT genotype. The correlations between the frequency of rs1544410 and rs2228570 and the COVID-19 prevalence and mortality were not significant.Conclusion: The variation in COVID-19 prevalence in the 26 populations included can be explained by the polymorphisms at the rs7975232 (ApaI) and rs731236 (TaqI) loci.