bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Bambara groundnut and butternut blend on proximate, mineral, beta-carotene and folic acid contents of sorghum flour
Authors: Kobue-Lekalake Rosemary , Gopadile Oduetse Daniel , Haki Gulelat Desse , Seifu Eyassu , Molapisi Moenyane , Sekwati-Monang Bonno , Gwamba John , Sonno Kethabile , Mokobi Boitumelo , Bultosa Geremew
Published: September 2022

The refined sorghum flour (SF) used is limited in fiber and micronutrients because of bran removal during milling, and protein digestibility is poor due to kafrin crosslinking. In this research, the effects of Bambara groundnut (BG) (15%, 25%, 35%) and butternut (BU) powder (23%) blending on SF were investigated, using 100% SF as a control. The proximate, mineral, beta-carotene and folic acid compositions of the flour mix were determined. As the BG levels increased, the protein, fat, fiber, and ash contents increased significantly (p < 0.05), ranging between 8.62–14.19%, 2.36–3.38%, 1.37–3.04% and 0.87–2.19%, respectively. The iron, zinc, calcium and phosphorus contents in mg/100 g were 3.43–5.08, 2.96–3.74, 80.00–106.67 and 150.63–594.53, respectively. The beta-carotene (mg/100 g) and folic acid (μg/100 g) contents were < 0.01–0.63 and 0.75–1.42, respectively. The mineral, beta-carotene and folic acid contents of the flour mix varied significantly (p < 0.05) from the control. The pro-vitamin A beta-carotene content was improved in the blend flours with the addition of BU powder, whereas, in the control sample, it was not detected (<0.01 mg/100 g). With the 35% BG blend, increases of 37% protein, 45% crude fiber, 48% iron, 26% zinc, 133% calcium and 154% folic acid contents from the control were observed. The study showed food-to-food fortification of SF with BG flour and BU powder has the potential to combat malnutrition, and the public health challenges associated with deficiencies in bioactive fibers, proteins and micronutrients (pro-vitamin A carotenoids, folic acid and minerals).
Deep arrhythmia classification based on SENet and lightweight context transform
Authors: Zeng Yuni , Lv Hang , Jiang Mingfeng , Zhang Jucheng , Xia Ling , Wang Yaming , Wang Zhikang
Published: September 2022

Arrhythmia is one of the common cardiovascular diseases. Nowadays, many methods identify arrhythmias from electrocardiograms (ECGs) by computer-aided systems. However, computer-aided systems could not identify arrhythmias effectively due to various the morphological change of abnormal ECG data. This paper proposes a deep method to classify ECG samples. Firstly, ECG features are extracted through continuous wavelet transform. Then, our method realizes the arrhythmia classification based on the new lightweight context transform blocks. The block is proposed by improving the linear content transform block by squeeze-and-excitation network and linear transformation. Finally, the proposed method is validated on the MIT-BIH arrhythmia database. The experimental results show that the proposed method can achieve a high accuracy on arrhythmia classification.
Synchronization control of time-delay neural networks via event-triggered non-fragile cost-guaranteed control
Authors: Wang Wenjing , Dong Jingjing , Xu Dong , Yan Zhilian , Zhou Jianping
Published: September 2022

This paper is devoted to event-triggered non-fragile cost-guaranteed synchronization control for time-delay neural networks. The switched event-triggered mechanism, which combines periodic sampling and continuous event triggering, is used in the feedback channel. A piecewise functional is first applied to fully utilize the information of the state and activation function. By employing the functional, various integral inequalities, and the free-weight matrix technique, a sufficient condition is established for exponential synchronization and cost-related performance. Then, a joint design of the needed non-fragile feedback gain and trigger matrix is derived by decoupling several nonlinear coupling terms. On the foundation of the joint design, an optimization scheme is given to acquire the minimum cost value while ensuring exponential stability of the synchronization-error system. Finally, a numerical example is used to illustrate the applicability of the present design scheme.
Preteklost in prihodnost
Authors: Breg Valjavec Mateja , Ciglič Rok , Čonč Špela , Geršič Matjaž , Perko Drago , Zorn Matija , Verbovšek Timotej , Tičar Jure , Šebela Stanka , Vrščaj Borut , Kastelic Peter , Bergant Janez , Medved Anže , Dolinar Mojca , Jemec Auflič Mateja , Bokal Gašper , Kumelj Špela , Jež Jernej , Volk Bahun Manca , Hrvatin Mauro , Komac Blaž , Mangafić Alen , Sivilotti Paolo , Lisjak Klemen , Čož Nejc , Fležar Urša , Hočevar Lan , Oliveira Teresa , Krofel Miha , Drešček Urška , Jež Jan , Drobne Samo , Degan Ajda Katarina , Švigelj Anton , Zrimšek Bernarda , Koblar Simon , Tiran Jernej , Razpotnik Visković Nika , Gabrovec Matej , Polajnar Horvat Katarina , Nared Janez , Šturm Tomaž , Gaberc Niko , Kop Boštjan , Golobič Nataša , Kolbl Eva , Jereb Planinšek Špela , Klement Jaka , Nograšek Sebastijan , Adamec Jakub , Polgár Michal , Švab Lenarčič Andreja , Brnot Marija , Duhovnik Marjana , Čotar Klemen , Dougan Jernej Nejc , Kokalj Žiga , Stegnar Gašper , Kovač Marko , Marsetič Aleš , Kanjir Urša , Novak Natalija , Jesenko David , Drešček Urška , Triglav Čekada Mihaela , Prah Klemen , Knez Matjaž , Mazej Tinkara , Repe Blaž , Krevs Marko , Žorž Grega
Published: September 2022

The book Preteklost in prihodnost ('The past and the future') is the sixteenth volume in the GIS v Sloveniji (GIS in Slovenia) book series and commemorates its 30th anniversary. The goal of the volume is to present the wide variety of research findings on geographical information systems in Slovenia in recent years. Powerful geoinformatic tools and precise data facilitate research on processes and phenomena, and their modelling. The volume presents project outputs and research results in areas such as geology, geomorphology, hydrology, pedology, agriculture, natural disasters, environmental protection, geography, surveying, archaeology, transport, telecommunication infrastructure, tourism, cultural heritage, education, cartography, geographical names, remote sensing, and others. Readers discover new features regarding the applicability of geographical information systems and learn about interesting research findings in many areas.
Exploratory Study of Societal Contexts and Industry Performance
Authors: Grant Delvin , Yeo Benjamin
Published: September 2022

There is inconclusive evidence on the effectiveness of information and communication technologies (ICT) at the industry level. Using the influence-impact model as a theoretical framework, the authors apply data mining techniques to identify ICT, financial, and geographical predictors of industry performance. The authors find that ICT are necessary but insufficient, and a mix of technical advancement, financial factors, and geography affect industry performance at different stages of development. These findings are used to discuss ICT for development (ICT4D) research, and abduct hypotheses for theory development with implications for future research.
Determinants of Employees' E-HRM Continuous Intention to Use
Authors: Ayyash Mohannad Moufeed , Herzallah Fadi A. T. , Alkhateeb Maan Ali
Published: September 2022

This work intends to examine the determinants of employees' continuous intention to utilize electronic human resource management (e-HRM) based on the technology continuous theory. Furthermore, it scrutinizes the direct and moderating effect of computer self-efficacy for the continuous intention to utilize e-HRM and how it moulds the direct relationship between perceived usefulness, attitude, and satisfaction. In this study, structural equation modelling (SEM) was used to examine the data obtained from a survey of 159 employees. The findings revealed that perceived usefulness, satisfaction, computer self-efficacy, and attitude had a direct and positive impact on continuous intention to use e-HRM. In addition, computer self-efficacy played a moderating role in the relationship between satisfaction, perceived usefulness, attitude, and the continuous intention to use e-HRM. The findings can be utilized by e-HRM service providers to devise strategies that can strengthen the employee's continuous intention and by scholars to increase, improve, and assess the research concerning e-HRM.
Perception About Online Classes Specific to Discipline and Living Locality of Students
Authors: Ramanujam Elangovan , Sundareswaran R. , Basha J. Jeelan
Published: September 2022

Online education has gained immense popularity among the working people and students pursuing higher education. Various renowned universities all over the world are offering online degrees and diplomas to all people through digital technologies. This enhances the concept of online classes due to the complete shutdown of educational institutions for an indefinite COVID-19 pandemic situation. Though the online classes are an immediate and emergency paradigm shifting in teaching and learning, it has certain drawbacks that concern the student to a larger extent. To examine the effects of online classes in terms of quality, comfort, and compatibility, this study analyzes the students' perception of various arts, science, and engineering colleges. Drawing on data from various students and its statistical test has inferred various challenges faced by the students with respect to their discipline and living locality. The result of statistical analysis recommends more improvisations and special considerations to the educational institutions to make this mode a viable solution.
Aerodynamic and Acoustic Design of the Joby Aviation eVTOL Propeller
Authors:   Joby Aviation, Bain Jeremy , Stoll Alex , Mikic Gregor
Published: September 2022

Joby Aviation is developing a six propeller, all electric vertical takeoff and landing aircraft for the Urban Air Mobility mission. The two primary design goals of this aircraft are safety and low noise. The aircraft is designed for high density operations near residences and workplaces, so it is imperative that the acoustic emissions of the aircraft are minimized for community acceptance. After flight testing the initial full scale prototype aircraft, a redesign process was undertaken to further improve the propeller acoustics. This process included rapid composite manufacturing to enable experimental tests of intermediate designs. The propellers were initially designed using a low fidelity lifting line and prescribed wake design code. Design studies were made based off this initial design using the high fidelity Navier-Stokes solver OVERFLOW and FW-H solver PSU-WOPWOP. This process resulted in an increased solidity, reduced tip speed, and a swept anhedral blade tip. The final design was tested and shown to have a 3 dBA decreased OASPL at a hundred foot radius and 45 degrees below the propeller plane in hover when producing the same thrust as the previous propeller design. The newly designed blade has been flight tested on the Joby production prototype aircraft.
Acoustics Analysis of a Quiet Helicopter for Air Taxi Operations
Authors:   University of California Davis, Li Sicheng , Lee Seongkyu
Published: September 2022

This paper investigates tonal noise and broadband noise for rotor designs used on urban air mobility vehicles. The rotor aerodynamics in edge-wise forward flight is calculated using the blade element theory, coupled with a dynamic inflow model and the moment-balance trim analysis. Loading noise and thickness noise are obtained using the lifting-line loading distribution and the dual-compact thickness noise model in PSU-WOPWOP.With the forward flight capability developed in UCD-QuietFly, broadband noise is obtained, including trailing-edge noise, trailing-edge bluntness noise, and airfoil stall noise. The air taxi designs, with varied tip speeds and the same mission specifications, are studied for their tonal noise and broadband noise. First, it is found that broadband noise is the dominant noise source for the rotor designs with low tip speeds and fewer blades, while tonal noise is dominant for the high-tip-speed designs. Second, for human hearing, A-weighting maintains the importance of broadband noise while reduces tonal noise significantly. Third, broadband noise is the dominant noise source for the rotor out-of-plane observers, while tonal noise is dominant for the in-plane observers. Fourth, both tonal noise and broadband noise increase proportionally with increasing the forward speed. Finally, low tip speed and more blades are found to be the preferable design features in terms of psychoacoustic metrics.
Structural Design and Aeromechanical Analysis of a Next-Generation Mars Hexacopter Rotor
Authors:   University of Maryland, Chi Cheng , Datta Anubhav , Lumba Ravi
Published: September 2022

Three-Dimensional (3D) aeromechanical analysis is carried out on the rotor blades of a 20 kg Mars Hexacopter. The objectives are to understand the aeroelastic behavior of its unique and ultra-thin low-Reynolds number and high-Mach number blades and study the interactions of structures, aerodynamics, and control moments in the Martian atmosphere. Beginning with structural analysis in vacuum, comprehensive analysis is carried out in hover and forward flight using 3D FEM, 2D airfoil tables, and free-wake. Natural frequencies of the rotor, elastic response of the blade, control momentoftheroot, airloads, wake, and 3D stresses are studied. Two types of designs are considered: a baseline design with pitch axis at the quarter chord and an unconventional design with the pitch axis moved to the mid-chord. Unusual nose-up elastic twist is observed on the rotor blades that appears to stem from the trapeze effect that counteracts the f lattening effect of the propeller moment. By moving the pitch axis to mid-chord, the control moment is reduced by 30%-40% without any noticeable adverse effect on stability due to the low Lock number. Both designs have maximum stresses well below the material limits but the mid-chord design has a more uniform distribution of stress in general and lower levels of shear stress in particular. These, and many other unconventional phenomena make Martian aeromechanics unique and ripe with possibilities of innovations tailored to its atmosphere.
Flight Dynamics Model Identification of a Meso-Scale Twin-Cyclocopter in Hover
Authors:   Texas A&M University, Runco Carl , Benedict Moble
Published: September 2022

In this paper a linear flight dynamics model of a micro twin cyclocopter is experimentally derived from flight test data and analyzed. The twin cyclocopter is a novel aerial vehicle that uses two cyclorotors spinning in the same direction to generate thrust, and a nose propeller to counter the reaction torque as well as provid additional thrust. This twin cyclocopter is unique for its size, design, and coaxial nose rotor that balances reaction torques along the vertical axis. AVICONmotion capture system was used to collect attitude and position data during perturbation maneuvers about hovering flight to excited the modes of the system. This data was used to extract a bare airframe linear time invariant f light dynamics model of the vehicle around the trim state, hover, using time-domain system identification techniques. The parameters of the model were derived using least squares between the states and control (regressors) and the outputs. The method of stepwise regression was used to add regressors to the model, and statistical metrics were used to determine the significance of the selected regressors. The model illustrates some unique flight qualities of this micro air vehicle. It is shown that the roll and yaw modes are gyroscopically coupled with a high and a low frequency mode, both of which are stable. Two different control methods for yaw are implemented and their differences quantified: thrust vectoring of the cyclorotors and differential torque of the coaxial nose. The former was shown to be more effective in controlling yaw. The coupled nature of the cyclocopter and unique configuration of control actuators presents opportunities for controls techniques to improve handling qualities.
Machine Learning Based Approach to Improve Low-Fidelity Predictions for a Compound Helicopter
Authors:   Rensselaer Polytechnic Institute, Makkar Gaurav ,   US Army Research Lab, Reddinger Jean-Paul , Gandhi Farhan , Kopsaftopoulos Fotis
Published: September 2022

A novel machine learning approach is introduced, with the goal of minimizing the number of points required to correct a low-fidelity model using sparse high-fidelity data. The method is applied to a low-fidelity comprehensive trim analysis of a compound helicopter with three degrees of control redundancy: main rotor speed, auxiliary thrust, and stabilator setting. The final low-fidelity correction model applies small changes to the power requirement and main rotor trim control predictions to more closely match the high-fidelity data. To reduce the computational time, and labor cost of querying the high-fidelity data, the algorithm prioritizes data acquisition by iteratively selecting the data where the error is expected to exceed the model tolerance by the greatest margin. The model is trained until the error model anticipates a scaled accuracy of 5% at the minimum power region at each flight speed, with no more than 20% error across the entire trim envelope. For the low-fidelity correction model, this tolerance is met through training with data from 89 trim states, which is a 79% reduction from the 428 trim states required to obtain comparable accuracy for a purely data-driven machine learning approach. Evaluation on a testing data set yields a rate of 95-98% of testing points actually falling within the error tolerance goals, compared to 80-93% for the purely data-driven model.
Recurrence and 5-year survival rate in patients with borderline ovarian tumors and related factors in Kurdistan
Authors: Sharami Seyedeh Reyhaneh Yousefi , Farhadifar Fariba , Tabatabaei Roya
Published: September 2022

The aim of this study was to investigate the recurrence rate and five-year survival in patients with borderline ovarian tumors and related factors. This retrospective cohort study was performed on 20 women diagnosed with a borderline ovarian tumor in Kurdistan province, Iran, between 2007 and 2019. Patients' records were reviewed and a researcher-made questionnaire was completed for each patient, which included demographic and clinical variables related to patient survival. The most common type of ovarian borderline tumor was the serous borderline ovarian tumor (75%). In fifty percent of the cases, cystectomy was used as th treatment. Recurrence was observed in three patients (15%), two of which were treated with cystectomy, and the other case was treated by TAH + BSO method (p = 0.64). There was no significant difference in terms of the type of surgery, history of infertility, history of taking contraceptive pills, age, age at diagnosis, and BMI between the two groups with and without recurrence (p > 0.05). The overall survival rate was 100% and none of the patients died at the end of follow-up. There was no relationship between any of the clinical and demographic variables with disease recurrence, and since all patients were alive after the end of the follow-up period. In summary, it was not possible to assess the relationship between patients' survival rate and studied variables.
Pedogeography of Canada
Authors: Putnam D F
Published: September 2022

L'auteur appuie, au début, sur le besoin d'études "pédogéographiques" au Canada, à la lumière du rôle important joué par l'agriculture dans le développement d_u pays. Puis on retrace, dans un bref historique,
l'opposition d s premières administrations provinciales et fédérales à de telles sciences et études et, l'intérêt graduel pour les sciences pédologiques après la fondation de l'Ontario Agricultural College en 1874. Les relevés des sols dans les
provinces sont compilés et cartographiés, montrant tout le territoire connu à l'heure actuelle, avec ses familles de sols, ses terres occupées, etc., et le territoire encor inconnu et non cartographié. Le territoire canadien est divisé en grandes zones ou domaines
pédologiques fondés sur les travaux, accomplis jusqu'ici. Ces zones sont décrites en tenant compte des facteurs suivants: associations végétales, climat, caractéristique du sol et utilisation présente. On compte dix grandes zones: 1 ° sols bruns, brun
foncé, 3° sols noirs, 4 ° sols gris boisé, 5° sols très calcaires, de la cordillère, 7° sols de la côte du Pacifique, 8° sols podzoliques brun et gris, 9° sol podzoliques bruns, 10° podzols. Enfin, on résume les différents
système de classification d s terres employés par les provinces, afin d'illustrer les techniques des agronomes et pédologistes canadiens, puis l'on cite les estimés de terre en fermes.
The shelters along the east coast of Lake Superior
Authors: Gutsell B V , Fraser J K
Published: September 2022

Les havres qui peuvent servir de reguge ou d'abri, le long de la côte est du lac Supérieur, entre l'embouchure de la rivière Montréal et la baie Héron, sont au nombre d'une vingtaine. Voila l'une des résultats d'une expédition
entreprise par le petit navire canadien C.G.S Bayfield, en 1949. Cette expédition avait pour but de découvrir et de signaler les principaux abris que les petits navires peuvent utiliser en cas de tempête, de grands vents ou d'accident, lorsqu'ils croisent le long de cette côte
inhospitalière. On a choisi six havres pour illustrer les trois types de refuges que l'on rencontre le plus souvent dans ces parages. Ce sont les havres situés à l'embouchure des rivières Montréal et Puckasaw, le havre de la baie naturelle de Ganley et celui de l'anse
Sinclair, enfin les abris qui résultent de la proximité des îles avec le rivage, espèeves de chenaux étroits et profonds, soit le havre des îles Agawa et celui de Mamainse.
A survey of single-country atlases
Authors: Nicholson N L
Published: September 2022

Les recherches préliminaires sur l'Atlas du Canada consistaient, au tout début, à étudier un certain nombre d'atlas nationaux et quelques atlas mondiaux. Les résultats de cette étude sont présenté dans cette article.
D'abord on détermine les dimensions et le poids des atlas, pour arriver à la conclusion qu'un atlas national ordinaire mesure 13 pouces de largeur et 17 pouces de hauteur et qu'il pèse environ 12 livres. Les cartes sont groupées par planche et chaque planche est détachable;
toutes les planches ont placées à l'intérieur d'une couverture spéciale et épaisse. On examine ensuite les principales projections et échelles. Une carte du Canada, incluant le nord de l'île Ellesmere, remplit exactement une feuille-planche ordinaire, si l'on
utilise l'échelle au 1/ 10,000,000° et la projection conique équivalente de Lambert à deux parallèles (parallèles nord du 49c et du 77° degré). Presque tous les atlas nationaux utilisent des échelles très simples pour leurs cartes régionales et
locales. Ces échelles sont des multiples ou des fractions de l'échelle de la carte de base. Enfin, la matière ou le contenu des atlas nationaux est catalogué d'après le sujet, premièrement, en quatre grandes parties (générale, physique économique et
sociale) et deuxièmement en trente-deux subdivisions. Les résultats sont groupés dans un tableau. Ces résultats sont discutés brièvement; on souligne le contenu de quelques atlas, l'importance et l'espace consacrés à certains sujets. En conclusion, on
définit un atlas national comme: " une collection de cartes qui décrit les propriétés physiques de la terre et des eaux, occupées et administrées par les citoyens du pays intéressé, en même temps que l'adaptation et l'utilisation de ces ressources
physiques par l'homme."
The climate of the Island of Newfoundland: a geographical analysis
Authors: Hare K
Published: September 2022

Cette étude sur le climat de l'île de Terre-Neuve intéresse plu le géographe que le météorologiste; en fait, elle est écrite pour lui, car l'auteur met en relief les principaux éléments du climat, comme la
température, le précipitations et l'humidité, et il explique les effets du climat sur la végétation et les transports. En décrivant le milieu physique, on attire l'attention sur l'influence de la mer sur le climat de l'île, par la présence du courant froid du
Labrador qui l'encercle presque complètement, du courant de Gaspé et la formation de glaces, en hiver, sur les eaux avoisinantes. Beaucoup de gens croient que les températures annuelles enregistrée à Terre-Neuve sont froides et inclémentes. L'analyse détaillée
des températures saisonnières démontre que le climat de l'île ressemble à celui de Montréal, en hiver, et qu'il se compare favorablement à celui d'Edmonton, en été. On étudie ensuite le cycle annuel du gel et du dégel; on définit la
période de dégel comme la période de l'année pendant laquelle la température moyenne reste constamment au-dessus de 32 degrés, et la période de gel comme la période correspondante ayant une température moyenne audessous de 32 degrés. Le dégel
s'effectue en avril et le gel e forme en novembre. On souligne les conséquences de la période sans gelée sur la végétation et l'agriculture, et celles de la période de gelée sur le transports d'hiver et la fermeture des ports locaux. L'humidité est
analysée d'après le rapport entre la vapeur d'eau et l'air sec de l'atmosphère, le minimum d'humitidé est enregistré en hiver, et le maximum en été. Les précipitations sont abondantes et bien réparties toute l'année; on note cependant, des variations
saisonnières; la moyenne de précipitation est de 50 pouces sur la côte et de 40 pouces dans l'intérieur. Il tombe plus de 100 pouces de neige par année. La saison agricole est tardive et plus courte que celle des environs de Montréal et des basses-terres du
Saint-Laurent, elle s'étend de la fin de mai et du début de juin à la fin de septembre et au début d'octobre. Ensuite on classe le type de climat en relation a naturelle, en particulier avec les essences forestières. On décrit, dans les dernières pages, les effets
climatiques sur l'accessibilité de Terre-Neuve par air et par mer. Dans le premier cas on analyse les conditions de visibilité, la hauteur des nuages, le dégagement du ciel et l'accroissement de la glace, dans le deuxième cas, on traite de la formation de la glace sur les eaux
environnantes, la présence de la brume et la vélocité et périodicité des vents. En appendice, on trouve une liste des stations météorologiques avec tableaux statistiques sur la température, les précipitations, etc., pour plusieurs
stations.
The physical basis of ranching in the interior plateau of British Columbia
Authors: Weir T R
Published: September 2022

On peut discerner, dans le plateau intérieur du sud de la Colombie Britannique, les principaux facteurs physiques propices à l'élevage des bestiaux, facteurs qui aident à déterminer les zones et les types d'élevage. Étudiant
d'abord le relief et le drainage, l'auteur divise le plateau en trois sous-régions: celle du nord, peu ondulée, marécageuse et pauvrement irriguée, celle du sud, mieux irriguée et au relief plus accentué, enfin une sous-région montagneuse située à la
périphérie des deux autres. Il distingue ensuite deux types de climats: un climat de steppe dans les basses terres et un climat continental et humide dans les hautes terres. Mais l'élément physique le plus important est la végétation naturelle, que ce soit une
végétation herbacée, en partie buissonneuse et arbustive ou, au-dessus, une végétation forestière. A ces facteurs il faut ajouter le cloisonnement des prés par des clôtures, la qualité et la quantité des fourrages et les restrictions légales.
L'étude de tous ces facteurs permet de diviser le plateau en quatre zones d'élevage: une zone d'hiver, inhospitalière et restreinte en étendue, située surtout dans le fond des vallées, une zone de printemps, une zone d'été, située au-dessous de
l'étage forestier, avec ses prés et ses pâturages alpins, enfin une zone d'automme qui est une zone de printemps encore intouchée ou broutée pour la deuxième fois. Telles sont les zones qui servent à l'élevage de plus de 100,000 têtes de bétail et de
30,000 moutons.
A vegetation map of the Carter Basin area, Lake Melville Lowlands, Newfoundland
Authors: Gadbois P , McKay I A
Published: September 2022

La présente carte fait voir les régions naturelles végétales d'une superficie restreinte de la rive méridionale du lac Melville; elle indique de plus Je comportement des grands types végétaux représentatifs des basses
plaines de débordement et des terrasses dans ce secteur du Labrador. On se basa sur ]a méthode du pourcentage d'humidité du sol pour la détermination des différents types végétaux, telle que décrite dans les ouvrages d'Hustich et de Rare: on a pu ainsi
établir des séries humides, semi-humides et sèches. Les principales essences végétales et leur distribution, qui est fonction du drainage de surface du territoire étudié, furent finalement envisagées.
Multidrug resistance in bacteria isolated from indoor air of female hostels in a tertiary institution
Authors: Adebayo-Olajide Testimonies Chikanka , Olorunfunmi Moriamo Olorunkemi
Published: September 2022

Objective:

To determine the occurrence of multidrug resistant bacteria from the indoor environment of female hostels in a tertiary institution in order to provide epidemiological data.

Methods:

The bacterial quality of the three female hostels was evaluated using the settle plate method, where Petri dishes containing different types of culture media were opened in the rooms. Isolated bacteria were identified using standard microbiological procedures. Using disc diffusion method, the antibiogram of the isolates was determined and based on this, the multiple antibiotics resistance index was also determined.

Results:

The total heterotrophic colony forming units (CFU) for Hall A ranged from 2.09 x102 to 1.73 x103 CFU/m3 while that of Hall B ranged from 4.71 x102 to 1.10 x103 CFU/m3 and a statistically significant difference between the counts of both halls was observed (P=0.04). Microorganisms isolated included Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Corynebacterium sp., Escherichia
coli, Klebsiella pneumoniae and Proteus
mirabilis. All the isolates exhibited multidrug resistance to amoxycillin-clavulanic acid, cefuroxime and ceftriaxone. Proteus mirabilis, Klebsiella pneumoniae and Corynebacterium sp. had the least multiple antibiotic resistance index with 0.2 while Staphylococcus aureus had the highest with 0.8.

Conclusions:

Female university hostels may become sources of exchange of microorganisms, especially in overcrowded rooms. A large percentage of isolates were multidrug resistant which could pose difficulty and increased cost of treatment of their resulting infections. Regular surveillance and control of the agents that encourage the growth of these bacteria present in indoor air is needed.
Postpartum Psychosis as a Presentation of Panhypopituitarism
Authors: Muralidharan Jananee , Tom Rose , Idiculla Jyothi
Published: September 2022

We describe a young patient diagnosed with postpartum psychosis, and managed with antipsychotics. She presented with hyponatremia after an episode of gastroenteritis. Further probing revealed a history of amenorrhea after the delivery. Workup showed panhypopituitarism. This treatable cause can mimic postpartum psychosis.
Coronavirus disease 2019 infection and neurological manifestations
Authors: Shrivastava Saurabh RamBihariLal , Shrivastava Prateek Saurabh
Published: September 2022

The coronavirus disease 2019 (COVID-19) pandemic has changed the dynamics of health care once for all, and we have to continue to mount an unprecedented response to eventually defeat the novel virus pandemic. A wide range of neurological manifestations have been reported among pediatric and adult patients with COVID-19 infection both during and after the patient has recovered from the illness. In terms of preexisting neurological conditions, people with these illnesses are not only vulnerable to acquire the novel viral infection, but at the same time are prone to experience an exacerbation of their preexisting illnesses, and also have poor treatment outcomes, including death. To conclude, a wide range of acute and postacute neurological manifestations have been attributed to the COVID-19 infection worldwide. This calls for the need to create awareness among health-care professionals about neurological symptoms and complications in the post-COVID period.
Promotion of eco-friendly Diwali
Authors: Nimbalkar Abhijit Vishwajit , Gothankar Jayashree Sachin , Patil Reshma Sachin , Pandve Harshal Tukaram
Published: September 2022

Background:

Diwali is a major festival in India and is celebrated with great enthusiasm and fervor. Due to bursting of firecrackers on large scale during Diwali releases harmful gases and toxic substances into the atmosphere leading to air pollution. It causes health problems for children, patients, and senior citizens.

Objectives:

The objective of this study was (1) To assess the knowledge, attitude, and practice of school-going students regarding the use of firecrackers. (2) To determine the prevalence of symptoms related to bursting of firecrackers among students and their families. (3) To find out the association between students' knowledge about health effects of firecrackers and their parents' education.

Materials and Methods:

An observational, cross-sectional study was done by using self-administered, validated, and pretested pro forma. The study was conducted in all schools located within 250 m2 of distance from the urban health training center of a private medical college. There were three schools falling under these criteria. All 8th standard students (215) of these three schools were included in the study.

Results:

Out of the total, 77% were boys. Many, i.e. 63% of students burst firecrackers during Diwali. The majority of students, i.e. 67% have knowledge about health effects of firecrackers. The majority, i.e. 80% of students promote eco-friendly Diwali celebration. The use of firecrackers was highly significant among boys (<0.001) and whose parent's education was below graduate level (<0.001). Symptoms of cough (30%), shortness of breath (22%), and eye injuries (3%) were reported due to bursting crackers.

Conclusions:

Overall knowledge about health effects of crackers was higher among students whose father's education was graduate and above. Thus, students have a positive attitude toward eco-friendly Diwali celebration.
Implementing a Combined Instruction Model on Pregnancy Options Counseling for Pre-clinical Medical Students
Authors: Brown Lucy D , Combs Sarah , McKinzie Alexandra , Barber McKenzie , Komanapalli Sarah , Wu Cynthia Y , Hardman Sara , Stout Julianne
Published: September 2022

Introduction:

The Association of Professors of Gynecology and Obstetrics (APGO) recommends that pre-clinical medical students learn how to counsel on pregnancy options as a standard learning topic during undergraduate medical curriculum.

Materials and Methods:

Second-year medical students viewed pre-recorded lectures and attended a panel on pregnancy options counseling covering adoption, abortion, and pregnancy continuation. Students were then surveyed about their experiences.

Results:

Participants (n = 57) were primarily female (74%), non-Hispanic (89%), and Caucasian (77%). Students determined that most (80–100%) of the APGO Student Learning Objectives were adequately covered by the panel and pre-recorded lectures. Students reported on a 5-point Likert-type scale a statistically significant increase (P < 0.0001) in their perceived preparedness to counsel across each pregnancy option category: abortion (2.17 ± 0.94 before vs. 3.5 ± 0.94 after), adoption (1.81 ± 0.86 before vs. 2.56 ± 1.04 after), and continuation of pregnancy (2.52 ± 1 before vs. 3.38 ± 0.95 after). Eighty-seven percent of the respondents felt that the panel was inclusive of diverse viewpoints.

Discussion:

Students appreciated the pre-recorded lectures and case-based panel as providing important exposure to pregnancy options counseling. Students noted a significantly increased preparedness to counsel a newly diagnosed pregnant patient on abortion, adoption, and pregnancy continuation, most notably with abortion counseling. The overwhelmingly positive reception of the panel highlights the desire of medical students to learn about these issues.

Conclusion:

This study demonstrates the efficacy of combined instruction modalities, including traditional didactics, case-based learning, and an expert provider panel, in educating students on pregnancy options counseling.
Short-Axis Imaging of the Pulmonary Valve through a Modified Parasternal View
Authors: Krishna Mani Ram , Sennaiyan Usha Nandhini
Published: September 2022

Background:

The aortic and pulmonary valves are both tricuspid valves. All cusps of the aortic valve can be imaged in the parasternal short-axis view but the pulmonary valve cusps are not routinely imaged during trans-thoracic echocardiography.

Methods:

We evaluated the feasibility of imaging all three pulmonary valve cusps in the short-axis by a modified parasternal view in 100 consecutive children below the age of 5 years.

Results:

A satisfactory short-axis imaging of the pulmonary valve was possible in 96 of 100 consecutive children in whom a complete echocardiogram study was performed. This detected abnormalities in the pulmonary valve in 10 children. This included bicuspid pulmonary valves, tricuspid pulmonary valves with unequal cusps, and a quadricuspid pulmonary valve. Visualization of the pulmonary valve permitted preoperative planning of pulmonary valve repair in one infant with a concomitant large ventricular septal defect.

Conclusion:

An adequate visualisation of the pulmonary valve leaflets by a modified parasternal view during trans-thoracic echocardiography was feasible in a vast majority of young children. The modified pulmonary short-axis view should hence be included as the part of a comprehensive pediatric echocardiographic protocol.
Investigating the Prognosis Gene Profile of Triple-Negative Breast Cancer
Authors: Chang Ya-Ting , Kao Li-Ting , Liao Guo-Shiou , Chen Ying-Chuan , Hu Je-Ming , Chang Yu-Tien
Published: September 2022

Background:

Current therapeutic strategies have poor effects in triple-negative breast cancer (TNBC) patients due to lack of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2 expression. Identification of novel genes of TNBC prognosis aids in the development of effective treatment strategies.

Aim:

We aim at explore key genes related to TNBC recurrence.

Methods:

RNAseq and clinical characteristics data were derived from The Cancer Genome Atlas Breast Invasive Carcinoma project. Ninety-seven TNBC patients were included. We used DESeq2 and Cox regression to identify significant genes to TNBC recurrence. Pathway enrichment analysis and protein–protein interaction plot were conducted to understand the functions of target genes.

Results:

We discovered top nine important genes for TNBC recurrence. Lower mRNA expression of potassium voltage-gated channel subfamily Q member 5, H3 clustered histone 10, and ADP-ribosylation factor-like protein 17 and higher mRNA expression of synuclein beta, interleukin 6 (IL-6), casein kappa, RHOC, phosphodiesterase 8B, and laminin subunit alpha 3 (LAMA3) were associated with higher risk of recurrence. IL-6, LAMA3, and Ras homolog family member V (RHOV) genes out of nine candidate genes can make the best prediction of TNBC recurrence (area under receiver operating characteristic curve: 0.95, sensitivity: 0.89 and specificity: 0.97). The top three significant Gene Ontology (GO) pathways are nucleosome, ion gated channel activity, and epidermis development. Significant GO pathways can be categorized into four functions: cell–cell adhesion, cell transportation, cell proliferation, ion channel and transporter, and immune.

Conclusion:

We discovered that the gene set of IL6, LAMA3, and RHOV can accurately predict TNBC recurrence. These genes warrant further study to confirm their causal association with TNBC prognosis and possible treatment targets.
Dynamic Somatosensory Evoked Potential and Magnetic Resonance Imaging in Pudendal Neuropathy
Authors: Örmeci Burcu , Uyanık Handan Uzunçakmak , Taşdelen Neslihan , Keleş Elif Çiðdem , Erdoğru Tibet , Öge Ali Emre
Published: September 2022

Aim:

Pudendal neuropathy (PN) is a common cause of chronic perineal pain and usually diagnosed long after the onset of symptoms. Diagnostic work-up of PN mainly includes radiologic and neurophysiological studies. However, there is no established diagnostic test to confirm the clinical diagnosis. This study aims to evaluate the correlation between the dynamic pudendal somatosensory evoked potential (SEP) and pudendal magnetic resonance imaging (MRI) in patients with PN diagnosed clinically based on Nantes criteria as the gold standard for comparison.

Methods:

Forty-three patients (25 females, 18 males) were included in the study. Dynamic pudendal SEP as a novel method, which includes both provocative positioning and stimulation of each side separately, and pudendal MRI were performed in each patient.

Results:

Dynamic pudendal SEPs were found to be abnormal in 42, normal in 12 of the 54 clinically symptomatic nerves and abnormal in 2, normal in 30 of the 32 clinically asymptomatic nerves. Pudendal MRI was abnormal in 19, normal in 35 of the 54 clinically symptomatic nerves and abnormal in 8 and normal in 24 of the 32 clinically asymptomatic nerves. There was 84% agreement between clinical diagnosis and dynamic pudendal SEP (high sensitivity and specificity), 49% agreement between clinical diagnosis and pudendal MRI (low sensitivity and acceptable specificity), 53% agreement between dynamic pudendal SEP and pudendal MRI.

Conclusions:

The novel dynamic pudendal SEP method seems to be useful in supporting the clinical diagnosis of PN, while pudendal MRI lacks sufficient sensitivity to be used alone in diagnosis of PN.
Localized tetanus mimics acute perforated viscus
Authors: Idris Iqlima , Mafauzy Mohamad Masykurin , Baharuddin Kamarul Aryffin , Alwi Farah , Mohamad Wan Syahmi Wan
Published: September 2022

Abdominal tetanus is the rarest presentation of localized tetanus in which other muscles are not involved. Proper diagnosis is challenging as it mimics acute abdomen. We describe the challenges in diagnosing this atypical localized tetanus in an adult and a review of case reports. Our patient is a 40-year-old male who presented to the emergency department with generalized abdominal pain for 3 days. His physical examination revealed a guarded abdomen with tenderness in the epigastric region, while systemic examinations were unremarkable. The initial diagnosis was acute abdomen with suspected perforated viscus. Subsequently, he developed arching of the back on day 3 of admission with markedly elevated serum creatine kinase levels. A diagnosis of localized tetanus was made, and an uneventful recovery was achieved after management. Clinicians should be aware of the atypical presentations of abdominal tetanus as it mimics acute abdomen. Early recognition and initiation of treatment significantly reduce morbidity and mortality risks.
The Patient Living With Diabetes
Authors: Bouwmeester Carla
Published: September 2022

Care of people with diabetes involves the management of co-morbid conditions such as obesity, renal disease, and cardiovascular conditions that may be more prevalent in some socioeconomic and racial or ethnic groups. The pharmacist needs to consider the patient™s perspective to optimize care for a person living with diabetes.
Part Six: Antidiabetic Medication Benefits Beyond Glucose Lowering in Older People
Authors: Pogge Elizabeth K. , Early Nicole K.
Published: September 2022

Older people with type 2 diabetes are at an increased risk for macrovascular (damage to arteries that can lead to myocardial infarction or stroke) and microvascular (damage to small blood vessels including retinopathy and nephropathy) disease. Since 2008, newly approved antidiabetic medications have been required to show cardiovascular safety as part of the US Food and Drug Administration approval process. Since this time, new data have emerged regarding the differences between agents in terms of reducing diabetes-related complications. Older people often are at risk for or currently have one or more diabetes-related complication. When managing antidiabetic medication in older people, it is imperative to consider the risk versus benefit of each medication and to use agents that have proven benefits.
The US Environmental Protection Agency Focus on Compliant Pharmaceutical Waste Management Now Includes Long-term Care
Authors: Smith Charlotte A. , Skibinski Kathleen , Livingston Monica
Published: September 2022

The article provides a summary of changes in the US Environmental Protection Agency’s (EPA) regulation of hazardous waste pharmaceuticals as they pertain to both long-term care-provider pharmacies and longterm care facilities. The article describes the EPA's Final Rule: Management
Standards for Hazardous Waste Pharmaceuticals and Amendment to the P075 Listing for Nicotine, which became effective in some states on August 22, 2019, and is slowly being adopted by states nationwide. The new rule applies to all health care settings, including provider pharmacies and, for
the first time, specifically refers to long-term care facilities as regulated entities. A major benefit of the Final Rule is the removal of over-the-counter nicotine gums, lozenges, and patches from regulation as a P-listed hazardous waste, which previously has had a major negative impact
on the hazardous waste generation status of health care facilities. Waste-generation parameters are provided to enable both provider pharmacies and consultant pharmacists to evaluate their specific practices to determine applicability. The biggest change is the removal of all hazardous waste
pharmaceuticals from the future calculation of generator status, thereby enabling facilities to meet the requirements of Very Small Quantity Generators or Small Quantity Generators of hazardous waste. All Small Quantity and Large Quantity Generators of hazardous waste must notify their state
of their generator status once the state adopts the Final Rule by completing Form 8700-12. This article provides a variety of references to provide The American Society of Consultant Pharmacists members with additional resources and information.
Geriatric Pharmacotherapy Case Series: Poly-Provider Leading to Polypharmacy
Authors: Matthews Megan E. , Evangelista Patricia , Gurvich Tatyana
Published: September 2022

Background: This case study reviews the complicated treatment of an older person under the care of numerous specialists in the ambulatory care setting. As various providers made concurrent changes in pharmacotherapy without communication with other providers, the patient
experienced acute changes and decompensation. Assessment: Polypharmacy played a significant role in the acute decompensation of the patient. Changes made in the context of specific specialties inadvertently had a negative impact on other disease states. Outcome:
Intentional communication between all providers on the patient’s health care team resulted in a deeper understanding of the overall plan and therapeutic goals. Care synchronization ultimately improved patient outcomes. The clinical pharmacy team provided multiple pharmacotherapy
recommendations to improve pain and anxiety without jeopardizing safety and therapeutics for other disease states. These interventions provided a key element that streamlined and improved patient-centered care. Conclusion: In this case, poly-provider was responsible for
polypharmacy that significantly impacted the patient’s care and quality of life. Pharmacists and the pharmacists’ patient care process play a significant role in improving patient-centered care by identifying medication changes and potential side effects, especially in the wake
of interventions by multiple providers.