bluuebunny/crossref_metadata_2025 huggingface dataset:
TABLE 2 from Perceived Appropriateness of Assessing for Health-related Socioeconomic Risks Among Adult Patients with Cancer
Authors: Vu Milkie , Boyd Kelly , De Marchis Emilia H. , Garnache Bridgette G. , Gottlieb Laura M. , Gross Cary P. , Lee Nita K. , Lindau Stacy Tessler , Mun Sophia , Winslow Victoria A. , Makelarski Jennifer A.
Published: May 2024

Sociodemographic and health care factors in relation to desire for assistance with HRSRs among a sample of patients with cancer
FIGURE 3 from Perceived Appropriateness of Assessing for Health-related Socioeconomic Risks Among Adult Patients with Cancer
Authors: Vu Milkie , Boyd Kelly , De Marchis Emilia H. , Garnache Bridgette G. , Gottlieb Laura M. , Gross Cary P. , Lee Nita K. , Lindau Stacy Tessler , Mun Sophia , Winslow Victoria A. , Makelarski Jennifer A.
Published: May 2024

Prevalence of desire for assistance with HRSRs among a sample of patients with cancer. A, Among those with the particular HRSR. B, Among the entire sample (N = 153; one participant had missing data for desire for assistance).
Supplementary Table S2 from Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
Authors: Lee Jin , Mashima Tetsuo , Kawata Naomi , Yamamoto Noriko , Morino Shun , Inaba Saori , Nakamura Ayane , Kumagai Koshi , Wakatsuki Takeru , Takeuchi Kengo , Yamaguchi Kensei , Seimiya Hiroyuki
Published: May 2024

Chemical compounds used for the screening
Supplementary Materials and Methods from Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
Authors: Lee Jin , Mashima Tetsuo , Kawata Naomi , Yamamoto Noriko , Morino Shun , Inaba Saori , Nakamura Ayane , Kumagai Koshi , Wakatsuki Takeru , Takeuchi Kengo , Yamaguchi Kensei , Seimiya Hiroyuki
Published: May 2024

Supplementary Materials and Methods
Supplementary Figure S6 from Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
Authors: Lee Jin , Mashima Tetsuo , Kawata Naomi , Yamamoto Noriko , Morino Shun , Inaba Saori , Nakamura Ayane , Kumagai Koshi , Wakatsuki Takeru , Takeuchi Kengo , Yamaguchi Kensei , Seimiya Hiroyuki
Published: May 2024

Estimation of ALDH1A3 gene amplification and the levels of biomarkers in 5-FU treated xenograft tumors
Supplementary Figure S5 from Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
Authors: Lee Jin , Mashima Tetsuo , Kawata Naomi , Yamamoto Noriko , Morino Shun , Inaba Saori , Nakamura Ayane , Kumagai Koshi , Wakatsuki Takeru , Takeuchi Kengo , Yamaguchi Kensei , Seimiya Hiroyuki
Published: May 2024

BRD4 knockdown suppresses 5-FU-induced ALDH1A3 upregulation.
Data from Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
Authors: Lee Jin , Mashima Tetsuo , Kawata Naomi , Yamamoto Noriko , Morino Shun , Inaba Saori , Nakamura Ayane , Kumagai Koshi , Wakatsuki Takeru , Takeuchi Kengo , Yamaguchi Kensei , Seimiya Hiroyuki
Published: May 2024

Abstract
Anticancer drug-tolerant persister (DTP) cells at an early phase of chemotherapy reshape refractory tumors. Aldehyde dehydrogenase 1 family member A3 (ALDH1A3) is commonly upregulated by various anticancer drugs in gastric cancer patient-derived cells (PDC) and promotes tumor growth. However, the mechanism underlying the generation of ALDH1A3-positive DTP cells remains elusive. Here, we investigated the mechanism of ALDH1A3 expression and a combination therapy targeting gastric cancer DTP cells. We found that gastric cancer tissues treated with neoadjuvant chemotherapy showed high ALDH1A3 expression. Chromatin immunoprecipitation (ChIP)-PCR and ChIP sequencing analyses revealed that histone H3 lysine 27 acetylation was enriched in the ALDH1A3 promoter in 5-fluorouracil (5-FU)-tolerant persister PDCs. By chemical library screening, we found that the bromodomain and extraterminal (BET) inhibitors OTX015/birabresib and I-BET-762/molibresib suppressed DTP-related ALDH1A3 expression and preferentially inhibited DTP cell growth. In DTP cells, BRD4, but not BRD2/3, was recruited to the ALDH1A3 promoter and BRD4 knockdown decreased drug-induced ALDH1A3 upregulation. Combination therapy with 5-FU and OTX015 significantly suppressed in vivo tumor growth. These observations suggest that BET inhibitors are efficient DTP cell–targeting agents for gastric cancer treatment.
Significance:
Drug resistance hampers the cure of patients with cancer. To prevent stable drug resistance, DTP cancer cells are rational therapeutic targets that emerge during the early phase of chemotherapy. This study proposes that the epigenetic regulation by BET inhibitors may be a rational therapeutic strategy to eliminate DTP cells.
Towards understanding the effect of work on teacher’s mental health: a mixed method study
Authors: Aziz Rahmat , Abdullah Irwan , Rahayu Iin Tri , Sa'diyah Elok Halimatus , Nashori Fuad
Published: May 2024

Working as a teacher significantly impacts mental health, both psychological well-being and psychological distress. This study examines the effect of working as a teacher on mental health. A mixed-method sequential explanatory design was chosen because it aims to test theories and provide detailed explanations for the results. Quantitative data were collected from 153 primary school teachers in East Java, and qualitative data were collected from 12 teachers who were purposively selected as interview subjects. The data were collected through interviews and four psychological scales (work commitment, engagement, job satisfaction, and mental health). Statistical inferential analysis and thematic analysis were used to analyse the data. The analyses showed that teachers’ jobs affected their mental health in terms of psychological well-being and psychological distress. Work commitment effected on mental health R=.653, R2=.426 p<.001; work engagements effected on mental health R=.479, R2=.230 p<.001; and job satisfaction effected on mental health R=.668, R2=.446 p<.001. The findings suggest that teachers’ mental health can be strengthened through their attitudes and behaviours towards work.
Distinct dietary patterns lead to lower B12 intake in type 2 diabetes: a case-control study
Authors: Rawat Swapnil , Kumari Meena , Nagpal Jitender
Published: May 2024

B12 deficiency has a higher prevalence in type 2 diabetes mellitus (T2DM) patients. The causes of this observation are poorly understood. Self-imposed (vegan/vegetarian) or advised dietary modification or intake of metformin could be contributing. Hence, we undertook this study to evaluate the dietary intake of Vitamin B12 in diabetes patients in comparison with age-matched healthy controls. Fifty T2DM patients (cases) and 50 age-matched volunteers (controls) aged 35-60 years were enrolled at a tertiary hospital, in New Delhi. Sociodemographic and dietary information was gathered and the average dietary intake of B12 was estimated using the Cobalamin Intake in North Indians-Food Frequency Questionnaire (COIN-FFQ) (developed and validated). Medical records were reviewed for biochemical parameters (HbA1c, lipid profile, and blood sugar) of the last three months. The mean age was 50.66±6.09 years (n=100) and the mean body mass index of 28.49±4.53 kg/m2. The mean intake of dietary B12 was 3.2±1.7 μg/day and 3.8±1.4 μg/day (p=0.047) in diabetes patients and controls respectively. Thirty-six percent of diabetes patients did not meet the currently recommended daily dietary intake of B12 intake (vs. 14% of controls; p=0.011). Diabetes patients have a lower dietary intake of Vitamin B12 attributable to their distinctive dietary pattern. It is necessary to explore the factors leading to lower dietary B12 intake in diabetes patients.
Adherence of inactivated polio vaccine immunization for children in Central Java Province
Authors: Sriatmi Ayun , Martini Martini , Patriajati Sutopo , Budiyono Budiyono , Handayani Novia , Kusumawati Aditya , Armunanto Armunanto
Published: May 2024

Indonesia is a country with high-risk polio transmission. Administering inactivated polio vaccination (IPV) after drops-polio or oral polio vaccination (OPV) was a strategy stopping polio transmission because its ability to ward off poliovirus which was very dangerous. The IPV coverage was very low and have never reached the target since it was launched in 2016. The study purpose was analyzing determinants factors of IPV adherence. A cross-sectional survey conducted in 31 districts in Central Java Province. Sample was 685 children aged 11-23 months and selected using purposive and accidental sampling method. Collecting data by interview using structured questionnaire and observation with maternal and child health (MCH) Handbook to identify immunization status. The collected data was analyzed univariate, bivariate, and multivariate. As many as 74.3% of children received IPV. Partially, variables of delivery history, immunization status, knowledge, attitudes, sources of information, and service satisfaction were related to IPV adherence. Simultaneously, immunization status, attitudes, and sources of information influenced IPV adherence with an overall effect 35.2%. Immunization status as the dominant influencing factor. Efforts were needed reducing resistance to IPV through psychological approach that was motivating and personal, also using of social media as a medium for positive information and communication, in addition to improve immunization service system.
Correlation of offspring thyroid function and maternal iodine status in iodine deficient-coastal area
Authors: Ekawanti Ardiana , As’ad Suryani , Natsir Rosdiana , Umar Husaini , Irawati Deasy , Kadriyan Hamsu , Zubaidi Fitriannisa Faradina , Ayunda Rahmah Dara
Published: May 2024

Thyroid hormone is vital for children's growth and metabolism, relying on sufficient iodine levels for synthesis. Maternal intake determines iodine supply to fetuses and children under two years old. This study aimed to correlate offspring thyroid function with maternal iodine status in coastal areas. A cohort study was conducted, involving pregnant coastal residents. Maternal urinary iodine levels were measured via the ammonium persulfate method, while offspring thyroid stimulating hormones (TSHs) and free thyroxine hormone (fT4) levels were assessed using electro-chemiluminescence immunoassay (ECLIA). Iodine intake was determined through a semiquantitative food frequency questionnaire (FFQ). The correlation between offspring thyroid function and maternal iodine status was analyzed using Pearson’s correlation test. Differences in TSHs and fT4 levels among iodine status groups were examined using the One way-ANOVA test. Maternal iodine status was insufficient with a median urinary iodine of 125 μg/L, resulting in a 60.8% prevalence of iodine insufficiency. Iodine intake (62.20±43.45 μg/day) fell short of recommended levels (RDA). Offspring TSH was 2.29±1.07 μIU/mL, fT4 was 1.26±0.14 ng/dL. TSH and fT4 concentrations showed no significant inter-group differences (p=0.852, p=0.075). Offspring thyroid function did not correlate with maternal iodine status (TSHs: p=0.314; fT4: p=0.258). Offspring thyroid function did not correlate to maternal iodine status in a population of iodine-insufficient and mercury-contaminated coastal areas.
Marching exercise on balance and blood pressure among Thai community-dwelling older adults at risk of falling
Authors: Boonsa-ard Wittawat , Chompoopan Worawut
Published: May 2024

Falls are a major cause of death among older people, and they are becoming a bigger problem as people lose their balance. A quasi-experimental study was conducted to examine the effects of marching exercises on the balance abilities of community-dwelling Thai seniors at risk of collapsing. Thirty-five participants were randomly assigned to the experimental or control group. The experimental group engaged in a 12-week marching exercise program that included a continuous foot-turning phase. The control group did not engage in any form of exercise. Compared to the control group, the experimental group demonstrated significant improvements in their ability to maintain their balance. The experimental group's timed up and go test (TUG) score decreased by 3.54 seconds, 95%CI: (2.13 to 4.95), p<0.001 while the functional reach test (FRT) score increased by 4.80 centimeters, 95%CI: (2.34 to 7.25), p<0.001. The systolic blood pressure decreased by 8.62 mmHg, the diastolic blood pressure by 6.48 mmHg, and the heart rate by 4.04 beats per minute. These findings imply that regular marching exercise may improve balance in at-risk older adults. Further research is necessary to clarify the effects of marching exercise on people diagnosed with chronic diseases.
Prevalence of COVID-19 vaccines side effects among health care workers in Kirkuk City, Iraq
Authors: Mohamdamen-Ameen Omed Hamarasheed , Hasan Nashwan Nadhim , Ismael Zhyan Abdullah
Published: May 2024

Frequent local and general side effects were revealed after vaccination with COVID-19 vaccine, which played a role in public confidence in and acceptance of the vaccine since the evidence source for the safety of the vaccines and their side effects were exclusively provided only from manufacturer-funded researches. This study aimed to assess the prevalence of COVID-19 vaccines side effects among health care workers in Kirkuk City, Iraq. This cross-sectional study was done in governmental hospitals in Kirkuk City/Iraq from May 7, 2022 to August 15, 2022 among 373 healthcare workers (only those who were vaccinated with the COVID-19 vaccine). The data were analyzed through the statistical package for social sciences (SPSS) program version 23.0. Total of 246 (66%) healthcare workers experienced at least one side effect following the COVID-19 vaccination. Reported side effects among females were higher (70.1%) than males (60.4%) and they were a little higher (67.2%) among participants with age ≤40 years. The most repeated side effects were general fatigue, injection site pain, and headache. In conclusion the majority of the reported side effects were mild to moderate in severity and not considered life-threatening. The rate of COVID-19 side effects was lower among the participants who received Sinopharm's COVID-19 vaccine in comparison to others vaccines.
Triglyceride to high-density lipoprotein cholesterol ratio as a marker of non-alcoholic fatty liver disease in type 2 diabetes
Authors: Dwitama Adiwinoto Robert , Pranoto Agung , Sugihartono Titong , Adi Soelistijo Soebagijo , Pratama Adiwinoto Ronald
Published: May 2024

Type 2 diabetes mellitus (T2DM) and non-alcoholic liver disease (NAFLD) shared a common feature, insulin resistance (IR), which is marked by a change in the lipoprotein fraction, namely increased triglycerides (TG) and decreased high-density lipoprotein cholesterol (HDL-C) levels. Blood lipids are routinely examined in T2DM patients; thus, our study aimed to investigate the performance of TG/HDL-C ratio values to identify hepatic steatosis, the earliest manifestation of nonalcoholic fatty liver disease (NAFLD), in T2DM patients. One hundred adult T2DM patients over 30 years old were recruited from the diabetes outpatient clinic at the Dr. Soetomo General Academic Hospital from August to October 2023. Data regarding sociodemographics, medication, glycosylated hemoglobin (HbA1c), lipid profiles, and FibroScan with controlled attenuation parameter (CAP) were collected from all participants. The group with hepatic steatosis (CAP≥237 dB/m) had a higher body mass index (BMI), higher TG levels, and TG/HDL-C ratio values. The TG/HDL-C ratio was significantly correlated with CAP values. Hepatic steatosis can be identified using the TG/HDL-C ratio with a cut-off value of 2.83 (sensitivity:72.4%; specificity:71.4%). An elevated TG/HDL-C ratio is associated with a higher risk (OR:6.562; p<0.05) of having hepatic steatosis. The TG/HDL-C ratio is a potential marker to predict NAFLD in T2DM patients.
Validation of supervisor support scale and work-life balance checklist in Malay Language among Malaysian working mothers
Authors: Hamzah Hazalizah , Ramlee Fatanah , Panatik Siti Aisyah , Chee-Seng Tan , Jalil Nurul Iman Abdul , Zulkifli Syara Shazanna
Published: May 2024

Working mothers burdened with work and household responsibilities face challenges with work-life balance, which could be empowered through supervisor support in the workplace. Therefore, it is vital to identify the impact of supervisor support on working mothers’ work-life balance. However, available instruments to measure both constructs for the Malay-speaking Malaysian population are dearth. This study assessed the psychometric properties of the Malay version of the supervisor support scale (SS-Malay) and work-life balance checklist (WLB-Malay) and investigated the relationship between these variables among Malaysian working mothers. Using purposive sampling, 200 working mothers (M=38.80, SD=8.43) for the pilot study and 275 working mothers (M=38.33, SD=7.86) for the actual study completed either an online or printed survey consisting of demographic information, the supervisor support scale, and the work-life balance checklist. Exploratory factor analysis conducted on the pilot study data reported a two-factor structure for WLB-Malay and one factor for SS-Malay. Similarly, confirmatory factor analysis confirmed the unidimensional factor of SS-Malay, and two factors of WLB-Malay: concerned about work, and self. Reliability was established with alpha, omega, and composite reliability values of more than .70. Discriminant validity was established with correlation values of less than .90, and concurrent validity was established with significant moderation positive association between constructs. Structural equation modelling reported a satisfactory model fit for both scales and identified a positive impact of supervisor support on work-life balance among Malaysian working mothers. Accordingly, both WLB-Malay and SS-Malay are culturally fit for Malaysian working mothers.
Spatial autocorrelation of dengue in relation to population density in Balangan District, Indonesia: an ecological study
Authors: Ridha Muhammad Rasyid , Yudhastuti Ririh , Ambar Garjito Triwibowo , Norjanah Norjanah , Juhairiyah Juhairiyah , Andiarsa Dicky , Norleyandi Untung
Published: May 2024

Dengue in Balangan Regency has the 2nd highest incidence rate (IR) in South Kalimantan at 126.64 per 100,000 population. This study aimed to determine the distribution pattern and conduct spatial analysis of dengue with population density in Balangan Regency. This quantitative research requires secondary data of dengue cases and Population Density in time series 2017-2021 with spatial analysis methods. The results showed that high dengue cases were in areas that had high density. Based on spatial analysis, dengue cases have a positive spatial relationship in 2017-2019 and a negative spatial relationship in 2020-2021 where dengue cases have a non-clustered distribution pattern (spread). Paringin City, East Paringin, Bungin, Maradap, Panggung, and Awayan villages are categorized as high-highly vulnerable to dengue. The findings of this study indicate that there is an influence of population density on the incidence of dengue. Monitoring of areas with high population density using spatial analysis is necessary for early detection of areas with high potential for dengue incidence.
Maternal risk factors for stunting in children aged 24-59 months
Authors: Dayani Tiara Rica , Widyantari Kadek Yuke
Published: May 2024

Stunting is a problem of growth and development disorders in children which is related to nutritional problems in the world. In 2022, 21.6% of children aged under five years in Indonesia were stunted. Several factors influence stunting, including environmental (social), household factors, maternal and child factors. The aim of this study was to determine maternal risk factors for stunting in children aged 24 to 59 months. This research, with a case control study design, involved 191 participants (91 stunted children and 100 non-stunting children). The results found that maternal factors associated with stunting in children aged 24-59 months included maternal height (P<0.005, OR 2.025), birth spacing (P<0.005, OR 1.912), gestational age (P<0.005, OR 2.622), history of illness during pregnancy (P<0.005, OR 2.453), and consumption of iron tablets during pregnancy (P<0.001, OR 7.600). In the multivariate analysis, consumption of iron tablets and maternal height were the factors identified as being most related to the incidence of stunting in children aged 24-59 months.
Assessment of demographic factors and mental health status: initiating a healthy campus program
Authors: Djannah Sitti Nur , Trisnowati Heni , Andriyani Andriyani , Akmal Akmal , Tino Marilou D. , Briones Jane T. , Siswanto Deny Hadi
Published: May 2024

Mental health issues have been essential in formulating global health policies for 30 years. The campus community is inseparable from the problem of mental health disorders, which can affect the work either students, lecturers, or staff. This research aimed to describe mental health conditions among the campus community based on demographic factors as an opportunity to initiate a healthy campus program. This study used a quantitative method with a cross-sectional design. The population was an academic community at a private campus in Yogyakarta, Indonesia. There are 347 samples taken by accidental sampling. The mental health instrument used the self-reporting questionnaire. There, 60.81% of respondents experienced psychological disorders, and 73.49% of respondents needed to be referred to a mental health professional regarding addiction, psychotic disorders, and post-traumatic stress disorder (PTSD). There was a significant relationship between demographic factors consisting of gender, age, type of work, employment status, education level, faculty, and emotional disorders with a p-value of <0.005. Moreover, age, gender, education level, type of work, and employment status related to mental disorders due to addiction, psychosis, and PTSD with a p-value<0.005. It is concluded that a large proportion of responders need a referral to a mental health expert. To promote a healthy campus, university officials should follow up with health promotion initiatives such as partnering with the local health office and public health center for additional treatment and improving policy support.
Importancia del conocimiento específico de los docentes sobre el TDA/H y su manejo en el aula de clase
Authors: Sánchez Álvarez Doris Omaira , Duque Hurtado Diana María , Manco Santamaría Magda Luz , Pareja Molina Alvaro Diego
Published: May 2024

El estudio explora, por una parte, el nivel de conocimiento que los docentes de tres colegios públicos de Envigado tienen del Trastorno por Déficit de Atención con o sin Hiperactividad (TDA/H), y por otra, la importancia y las implicaciones que ello conlleva en la interrelación que mantienen con los estudiantes de sexto grado, que tienen este trastorno. Si bien los docentes pueden poseer un conocimiento suficiente sobre el tema, es en el manejo del tratamiento con medicamentos y en la estabilidad de los docentes en los procesos de enseñanza en dicho grado, en donde puede haber problemas que es necesario identificar y solucionar. En este sentido, se evalúan también los factores socio-demográficos, personales y laborales que pueden incidir en la manera como se interrelacionan los docentes con sus estudiantes, para plantear recomendaciones a los diferentes actores de la comunidad educativa, en especial a las directivas, a los propios docentes para que, conjuntamente, planteen y pongan en marcha estrategias que mejoren las prácticas pedagógicas y con ello se mejore la formación integral de los estudiantes y consecuencialmente su calidad de vida.
Perfil de valores en estudiantes de licenciatura de la Universidad de los Llanos
Authors: Chávez Ávila Patricia
Published: May 2024

Los propósitos de este trabajo son: dar a conocer el perfil de valores de los estudiantes de licenciatura de la Universidad de los Llanos, identificar la importancia relativa que conceden a cada valor y formular líneas de acción frente a la formación integral del educando. Se trata de un estudio descriptivo con tendencia cualitativa que se desarrolló en dos fases: en la primera fase se utilizó la escala de medición “Estudio de valores” de Gordon W. Allport y Phillip E., aplicada a una muestra de 432 estudiantes, 249 mujeres y 183 hombres. En la segunda fase, se desarrollaron ocho grupos focales de discusión, cuatro conformados por estudiantes y cuatro por docentes. El perfil de las estudiantes muestra una tendencia hacia estilos de valor económico y teórico, en promedio, los valores sociales, políticos y religiosos, y una baja puntuación en lo estético. El perfil de los estudiantes señala una tendencia hacia valores de tipo social, en promedio, los valores teóricos, económicos, estéticos y religiosos, y una puntuación baja en el político. Las líneas de acción en las cuales la universidad debe trabajar para favorecer la formación integral de sus educandos giran en torno a cuatro categorías que en orden de importancia son: docencia, proyección, bienestar y comunicación.
Psychotria pendens (Rubiaceae, Psychotrieae), a new ultramafic species from Central Palawan, Philippines
Authors: BAUTISTA MARY ANN C. , CHUA-MANGUSSAD VERNALUZ , CERVANCIA JEHSON , BUSTAMANTE RENE ALFRED ANTON
Published: May 2024

Psychotria pendens from the lowland ultramafic forest of Mt. Victoria, Palawan Island, Philippines is herein described as a new species of Rubiaceae. The new species is morphologically similar to P. rubiginosa (Gitingensis species group) by having monochotomous inflorescence and oblanceolate to oblong-elliptic leaves but is distinguished by its large, leaf-like, valvate stipules with biattenuate to biacuminate tips, pendent inflorescence, glabrous abaxial leaf surface, narrowly triangular bracts, and glabrous calyx. Molecular analysis revealed that this newly discovered species belongs to the Pacific Psychotria clade, and is allied to the Philippine species P. luzoniensis and Hawaiian species P. mariniana. The species is assessed as Critically Endangered (CR) based on the IUCN Red List categories and criteria.
A new species of the spider genus Mexentypesa Raven (Araneae: Nemesiidae) from Hidalgo, Mexico and taxonomic comments on M. chiapas Raven
Authors: SALINAS-VELASCO HÉCTOR VICENTE , VALDEZ-MONDRAGÓN ALEJANDRO , BUENO-VILLEGAS JULIÁN
Published: May 2024

A new species of the enigmatic spider genus Mexentypesa (Raven, 1987) from a cloud forest in Hidalgo state, Mexico is described: M. hidalguensis sp. nov. The description of the species is based on both male and female adult specimens. This discovery increases the diversity of the genus to two species: Mexentypesa chiapas (Raven, 1987) and the new species described herein. Additionally, Aptostichus sabinae syn. nov. (=M. chiapas), which was previously described as a different species, is formally synonymized.
A new species of Aegus Macleay, 1819 (Coleoptera: Lucanidae: Lucaninae: Aegini) from Thailand with checklist of the genus species from the country
Authors: PATHOMWATTANANURAK WUTTIPON , JIARANAISAKUL KAWIN
Published: May 2024

In this study, Aegus occidentalis Pathomwattananurak & Jiaranaisakul, new species is described from Tenasserim Range, western Thailand. Its habitus and genitalia are illustrated and compared with its closest relatives for both sexes. A checklist of the species of Aegus Macleay, 1819 (Coleoptera: Lucanidae: Lucaninae: Aegini) from Thailand is provided, which includes three new country records: Aegus babai Nagai, 1994, A. insignis Nagel, 1941 and A. laticollis Arrow, 1943. Additionally, a new junior synonym, Aegus chelifer Macleay, 1819 = Aegus chelifer crassodontus Bomans, 1992 new synonym, is proposed. Distribution maps of Aegus species in Thailand are also provided.
To the knowledge of the subtribe Pericalina Hope, 1838 (Coleoptera, Carabidae, Lebiinae), with description of new genus, new subgenus and species from Oriental region
Authors: ANICHTCHENKO ALEXANDER
Published: May 2024

A new genus Acoptodera gen. n. is described to place Coptodera piligera Chaudoir, 1883 previously attributed to genus Trichocoptodera Louwerens, 1958, as well as new subgenus Pericalocephala subgen. n. to place remarkable new species from Vietnam: Acoptodera (Pericalocephala) paradoxa sp. n. By the presence of hairs on head, pronotum and elytra, new genus is similar with Trichocoptodera Louwerens, 1958, but can be easely distinguished by flattened pronotum with wide lateral margins and by rounded elytra with serrate edges and fringe of setae on the sides. The status and characters of genera thought to be near relatives of Coptodera genus-group, are briefly discussed. Images of habitus and genitalia are provided.
Two new species of the comb-footed spider genus Lasaeola Simon, 1881 (Araneae: Theridiidae) from China
Authors: TANG GANG , LIU FENG , LIU ZI-YUE , YANG SU-FANG , PENG XIAN-JIN
Published: May 2024

Two new species of the spider genus Lasaeola Simon, 1881 are described from China based on both sexes: Lasaeola pinna n. sp., and Lasaeola tengchongensis n. sp. Distribution data, detailed morphological characteristics, and illustrations of body and genital organs are presented.
The morphology of the preimaginal stages of Choreutis muhabbet Koçak, 2008 (Choreutidae, Lepidoptera)
Authors: BĄKOWSKI MAREK , KEMAL MUHABBET
Published: May 2024

This work presents the first description of the last instar larval and pupal morphology of the metalmark moth species Choreutis muhabbet Koçak, 2008. All diagnostic morphological features are described in detail, and illustrated with photographs and line drawings.
Diagnostic features for the genus Choreutis (Hübner) based on the described last instar larvae and pupae, are proposed and discussed. We compare the description of larval and pupal morphology of C. muhabbet to known morphological features of the preimaginal stages of other Choreutis species, especially with Choreutis pariana (Clerck).
The Free-Running Circasemilunar Period Is Determined by Counting Circadian Clock Cycles in the Marine Midge Clunio Marinus
Authors: Neumann Jule , Rajendra Dharanish , Kaiser Tobias S.
Published: May 2024

Semilunar rhythms are found in numerous marine organisms, but the molecular mechanism and functional principles of endogenous circasemilunar clocks remain elusive. Here, we explore the connection between the free-running circasemilunar clock and the circadian clock in the marine midge Clunio marinus with three different chronobiological assays. First, we found that the free-running circasemilunar period of the adult emergence rhythm in C. marinus changes linearly with diel T-cycle length, supporting a day-counting mechanism. Second, under LD 6:6, periods of circasemilunar and circadian emergence were comparable to those under LD 12:12, indicating that the circasemilunar counter in C. marinus relies on endogenous circadian oscillations rather than external T-cycles. Finally, when desynchronizing the circadian clock with constant light, the free-running circasemilunar emergence rhythm disappeared as well, suggesting that it requires a synchronized circadian clock. These results oppose the long-held view that C. marinus’ free-running circasemilunar clock operates independently of the circadian clock. In a broader evolutionary context, our results strengthen the idea that the circasemilunar clocks of dipterous insects are based on different functional principles compared to the circasemilunar or circalunar clocks of marine annelids and algae. These divergent clock principles may indicate multiple evolutionary origins of circasemilunar and circalunar clocks.
Behavioral Problems Associated with Digital Screen Exposure in Children Aged 2–5 Years: Cross-sectional Study
Authors: Kaur Nimran , Gupta Madhu , Kiran Tanvi , Malhi Prahbhjot , Grover Sandeep
Published: May 2024

Objective:

To assess the emotional problems associated with digital-screen exposure (DSE) among 2–5-year-old children in Chandigarh, North India.

Methods:

A cross-sectional study was conducted among 400 randomly selected families with children aged 2–5 years using the validated DSE questionnaire and the standard preschool-child behavior checklist from October 2017 to March 2018. The American (2016) and Indian (2020) Academy of Pediatrics guidelines were followed to define excessive DSE. To estimate the probability for the predictors of emotional problems with DSE, we performed the per-binary multivariate logistic regression model, giving an adjusted odds ratio (AOR), using IBM SPSS Statistics for Macintosh, Version 25.0.

Results:

The mean age of the children was 3.5 years (standard deviation = 0.9). Nearly 15% of children were with borderline/clinical cases of emotional problems. The significant protective factors for individual emotional problems among children were watching learning media content [Oppositional defiant disorder (AOR = 0.39 CI 0.22, 0.72, p = 0.002)], having DSE less than one hour [Attention deficit hyperactivity disorder (AOR = 0.19 CI 0.08, 0.43, p<0.0001)], presence of media rules at home [Sleep problems (AOR = 0.03 CI 0.001, 0.69, p = 0.028)], age of initiating DSE before two years [Total emotional problems (AOR = 0.5, 0.22, 0.93, p = 0.03)], and caregivers DSE of less than two hours per day [Depression (AOR = 0.04 CI 0.002, 0.75, p = 0.031)]. While the significant predictors were playing outdoors almost every day [Total emotional problems (AOR = 2.2 CI 1.06, 4.78, p = 0.034)], average activity of less than 30 minutes per day [Total emotional problems (AOR = 2.4 CI 1.22, 4.73, p = 0.01)], boys [Total emotional problems (AOR = 2 CI 1.08, 3.55, p = 0.028)], children aged less than 3.5 years [Total emotional problems (AOR = 1.9 CI 1.05, 3.59, p = 0.03)] and higher socio-economic status [Withdrawn (AOR = 5 CI 1.19, 20.97, p = 0.028)].

Conclusion:

There was a moderate prevalence of emotional problems among children with excessive DSE. Specific emotional problems were significantly associated with the DSE among children.
Anaesthetic Management for a Dilated Cardiomyopathy Patient, Scheduled for Lumbar Spine Surgery
Authors: Srivastava Vinit K. , Gangireddy Hareendranath , Hamsa Vellore Srikanth , Krishna Yethirajyam Rama
Published: May 2024

Background:

Dilated cardiomyopathy (DCM) is characterized by dilatation and impaired contraction of left or both ventricles. Diagnostic criteria are left ventricular ejection fraction less than 40% or fractional shortening less than 25%. Perioperative anesthetic management of these patients are very challenging for anesthesiologists and intensive care team.

Case presentation:

A 55-year-old female, presented with complaints of severe low-back ache with bilateral lower limb involvement without involvement of bladder and bowel. Severe cord compression at the L4-5 level and severe lumbar canal stenosis were detected by magnetic resonance imaging. Echocardiography showed that the left ventricle (LV) had global hypokinesia, with an ejection fraction of 25% to 30%. The planed surgical procedures were L4 lumbar laminectomy and L4-5 microdiscectomy.

Conclusion:

Continuous monitoring and control of hemodynamic parameters as well as central venous pressure guided fluid therapy is the cornerstone in improving outcome in patients with dilated cardiomyopathy for non-cardiac surgery.
The Inequality in Healthcare Access in Bihar: Pattern and Determinants
Authors: Ahmed Shakeel
Published: May 2024

Healthcare access varies across socioeconomic determinants and therefore, states’ demographic and socioeconomic structure plays an important role in an individual’s health status in the state. For example, richer have better access to healthcare than poorer, and women have lower healthcare access than men. In this study, the role of socioeconomic determinants in healthcare access is discussed in five states of India—Jharkhand, Uttar Pradesh, Odisha and Madhya Pradesh; therefore, this article aims to determine how healthcare access across socioeconomic determinants varies across states. The study is based on the National Sample Survey 75th round of data on health (2017–2018). A comparative study is conducted to know the percentage of non-access to healthcare (unmet needs) across different socioeconomic determinants such as age, gender, income, religion, caste and others. A logistic regression model is used to determine significant socioeconomic factors in healthcare access in all five states. The concentration index and concentration curve show the inequality in healthcare access across income quintiles. The result shows that Bihar has the highest cases of non-access to healthcare across most socioeconomic determinants followed by Odisha and Jharkhand. In addition, cases of non-access to healthcare in all five states are largely higher than the national average. The result further shows that only a few socioeconomic determinants such as income class and caste are significant to healthcare access and state-wise, they vary.

JEL: I140; I150; I18
In Utero Extrahepatic Bile Duct Damage and Repair: Implications for Biliary Atresia
Authors: de Jong Iris E. M. , Wells Rebecca G.
Published: May 2024

Biliary atresia (BA) is a cholangiopathy affecting the extrahepatic bile duct (EHBD) of newborns. The etiology and pathophysiology of BA are not fully understood; however, multiple causes of damage and obstruction of the neonatal EHBD have been identified. Initial damage to the EHBD likely occurs before birth. We discuss how different developmental stages in utero and birth itself could influence the susceptibility of the fetal EHBD to damage and a damaging wound-healing response. We propose that a damage-repair response of the fetal and neonatal EHBD involving redox stress and a program of fetal wound healing could—regardless of the cause of the initial damage—lead to either obstruction and BA or repair of the duct and recovery. This overarching concept should guide future research targeted toward identification of factors that contribute to recovery as opposed to progression of injury and fibrosis. Viewing BA through the lens of an in utero damage-repair response could open up new avenues for research and suggests exciting new therapeutic targets.
Decoding BCOR-ITD Sarcomas: Case Report of a Rare Pediatric Tumor With Challenges in Diagnosis
Authors: Medina-Ceballos Emilio , Niveiro María , Ureña-Horno Laura , Sesé Marta , Tasso María , Navarro Samuel , Garrido-Pontnou Marta
Published: May 2024

Sarcomas characterized by BCOR gene alterations, are a distinct clinico-pathological group of high-grade tumors, that represent 5% of small round cell tumors without EWSR or FUS fusion. Diverse genetic alterations characterize this group, including BCOR-CCNB3 gene fusion being the most common alteration and less frequently internal tandem duplications (ITDs). We present a compelling case of a 3-year-old girl diagnosed with a high-grade nasoethmoidal sarcoma exhibiting BCOR-ITD. The diagnostic process illustrates the histological and immunophenotypic spectrum, requiring an extensive immunohistochemical panel and diverse molecular tests for accurate classification. Additionally, this case highlights the challenges in detecting BCOR-ITDs using different NGS panels, advocating for alternative molecular approaches. Our patient after 10 months since diagnosis is alive with progressive disease. This emphasizes the urgency for ongoing research to refine diagnostic methods and develop effective therapeutic strategies for these rare and aggressive tumors.
Music cooperating teachers’ perceptions of the university-cooperating teacher partnership
Authors: Baugh Molly K , Conway Colleen M
Published: May 2024

The purpose of this study was to examine three music cooperating teachers’ perceptions of the university-cooperating teacher partnership. Using a phenomenological interview design, data included two focus group interviews (framing the student teaching semester) and an individual interview in the middle of the term. Participants were experienced cooperating teachers who were working with a student teacher in the research study term and had worked with student teachers in the past. Findings include cooperating teachers’ perceptions of their roles, the balance of P–12 student and student teacher learning, and university and cooperating teacher interactions. Conclusions support the notions that cooperating teachers embrace their multi-faceted role in teacher education, prioritize P–12 student learning, and desire deeper connections with the university.
Examining the Link Between Entrepreneurialism and Employability: A Literature Review
Authors: Jain Amita , Singla Ankita
Published: May 2024

Policymakers and higher education institutions share global concerns about unemployment and equipping companies with a quality workforce. The dynamism of today’s business world has changed the nature of employability. In order to survive in this frequently changing business world, graduates must not only focus on their employability skills but also on entrepreneurial attributes. This article tries to understand the connection between entrepreneurship and employability. In like manner, this article carries out a review of literature in these two fields relying upon the Scopus database. This study extracted the final corpus of 236 articles and processed it further in Vos Viewer to know the most influential authors, countries, organisations and articles followed by an extensive review of 40 articles. This study reveals that the employability literature and entrepreneurial literature are mainly connected through entrepreneurship education and entrepreneurial skills. This study also offers future research direction by exposing some research gaps. This article will help higher education institutions understand the need to develop entrepreneurialism among graduates to enhance their employability.
The Impact of Gamification Depth on Higher Educational Students’ Intrinsic Motivation and Performance Levels
Authors: Yie Darren Lim , Sanmugam Mageswaran , Yahaya Wan Ahmad Jaafar Wan , Khlaif Zuheir N
Published: May 2024

Most studies on gamified learning have neglected gamification depth, which has motivated the current study to identify the impact of gamified depth on students’ intrinsic motivation and performance levels. A quasi-experimental approach was employed, which involved a total of 117 undergraduate students divided into control ( n = 57) and experimental ( n = 60) groups. The students were exposed to two gamified platforms, namely Kahoot! for shallow gamification and Classcraft for deep gamification, over four weeks. The Intrinsic Motivation Inventory (IMI) served to measure changes that occurred in students’ intrinsic motivation levels and the achievement test in the final lesson. Paired t-tests, an independent t-test and regression analysis were conducted to test the study hypothesis. Deep gamification significantly increased learners’ intrinsic motivation level (+0.1845), while shallow gamification decreased it (−0.6439). Contrarily, students in the shallow gamified learning environment achieved a higher performance with a mean value of 73.42 compared to the counterparts in a deep gamified environment (50.83). Students’ language mastery, interest, attitude and familiarity with technology were postulated to impact the study outcomes. Distinct subjects, age groups and a suitable experiment period are recommended for future studies to develop a proper gamified depth framework in the educational sector.
Becoming Changemakers: How Social-Emotional Learning Can Enhance Civic Agency Development
Authors: Nachtigal Tom , Zetlin Ariana , Shen Lisa Utzinger
Published: May 2024

To better prepare students for active and thoughtful participation in a democratic society, civic education should foster an array of civic competencies. Cultivating student civic agency—an under-studied civic competency—is of particular importance to equip students to authentically use their voice in their communities. But what does it look like to foster student civic agency in a classroom setting? This article leverages a social and emotional learning (SEL) framework to uncover the active curricular ingredients and educational mechanisms through which a student-led civics curriculum has fostered civic agency. In this multi-site case study, we analyze the implementation of an eighth grade student-led civics curriculum in a northeastern U.S. state. We outline how implicit SEL processes in these classrooms, stemming from a pedagogical focus on “changemakers,” supported development of civic agency. We found that the changemakers theme facilitated student exploration of their own civic identity and values, while prompting students to critically examine political power structures. Notably, the theme also helped students to develop a narrative of self as changemakers and to envision themselves actively engaged in civic spaces. This study adds insights to growing evidence on the multi-faceted benefits that civically-oriented SEL may offer to preparing young people to engage in democracy.
Status Quo of Artificial Intelligence’s Role in the HRM Operations
Authors: Khan Mohsin , Reddy V. Vijay Kumar
Published: May 2024

Coexistence of technology and business dates back to the late 18th century when the first ever use of a computer was for recording the census by the US government in 1890. The use of technology in business can be ascribed to different organisations in the different nations on the parallel lines of time. It includes invention of cash machines and their use by Barclays in England in the early 1960s, the induction of telephone-based modems for order management by Baxter Pharmaceuticals and use of small desktop computing device called Minitel for processing customer orders in France were the other notable developments in the history of coexistence of technology and business. Increasing operations in the business functions have created an urge for the technological innovation in the industry to handle the operations electronically. Figueiredo and Cohen (2019) say that technology has become an indispensable component of every business function by delivering ease in operations and productivity. The end of the 20th century had witnessed the leaping progress in computing in the form of artificial intelligence (AI) performing the tasks that were unimaginable to comprehend a decade back in time. Developments in the technological research and development prove that organisations have started inducting AI into as many fields as possible at a considerable pace. As a part of the shifting technological dynamics in the industry HR function has also transformed digitally. Tools like enterprise applications have forayed intensely into the operations of human resources management (HRM). These enterprise resource planning (ERP) tools remain to primarily serve the integration of HRM to the other functions. However, enterprise tools could not serve the purpose of supporting decisiveness in the areas of HR planning, workforce design and performance management at large. However, Tuck (2019) argues that AI is assuming increased responsibilities in the different sections of the society and business including the HRM function. At present, the amount of knowledge on the status quo of the role of AI in the HRM functions is scarcely available. Literature related to this disruptive technology in the HR function is still at the nascent stage. This study will examine the role of AI as a key component in the HRM function, which is regarded to be highly human-driven.