bluuebunny/crossref_metadata_2025 huggingface dataset:
Solanum pubescens Wild Fruits Essential Oil - A Golden Casket for its
Antimicrobial and Anti-inflammatory Mediated Wound Healing Efficacy
in Vertebrate Model Mus musculus
Authors: Rahman Haseebur , Rahman Nazneen , Haris Mir , Pradhoshini Kumara Perumal , Shareef Mohamed Ahadu , Musthafa Mohamed Saiyad , Rajagopal Rajakrishnan , Alfarhan Ahmed , Thirupathi Anand , Chang Soon Woong , Balasubramani Ravindran
Published: April 2022

Background:

Solanum pubescens Willd, growing wild in the hills of Rayadurg jurisdiction of Southwestern Andhra Pradesh, has gained significant attention among researchers for its diverse folkloric applications, existence of novel phytochemicals and leaf extracts which hold great medicinal promises. To date, the S. pubescens fruit’s essential oil (SPO) has never been investigated.

Methods:

The current research has been focused to evaluate the chemical composition of S. pubescens fruit essential oil through Gas Chromatography–Mass Spectrometry (GC-MS), followed by the investigation of antibacterial, antifungal, anti-inflammatory, analgesic and wound healing activities in appropriate models to uncover its biological potentials. Extraction of (Solanopuboil/SPO) from the fresh unripe fruits of Solanum pubescens was carried out in Buchner funnel and Whatman no.10 filter paper and concentrated at 40oC using a rotary evaporator. The metabolic proﬁling of SPO was analysed by GC–MS technique. The MIC, MBC, activity index, and total antimicrobial activity of SPO were evaluated using standard procedures. Anti-inflammatory activity of SPO was screened using Carrageenan induced paw oedema and Cotton pellet-induced granuloma. Tail immersion test, Acetic acid writhing response and Formalin paw lick test was performed in rats in order to examine the analgesic activity of SPO. Wound healing activity of SPO was investigated by performing the incision wound model, Excision wound model and Dead space wound model in rats.

Results:

The SPO displayed a constant degree of antimicrobial activity against B. cereus, B. subtilis, E. coli, A. niger, A. fumigatus and C. albicans with significant anti-inﬂammatory and analgesic activities. Also, a prominent wound healing potential of it was observed in
excision, incision and dead space wound models with considerable elevation in granulation tissue hydroxyproline, hexuronic acid and hexosamine content in association with remarkable regulation of anti-inflammatory and antioxidant markers i.e., Lipid peroxidase (LPO), Nitric Oxide (NO), Superoxide dismutase (SOD), Glutathione (GSH), Catalase (CAT), Glutathione Peroxidase (GPx).

Conclusion:

These findings strongly validate the therapeutic potential of S. pubescens fruit essential oil in antimicrobial and anti-inflammatory mediated wound healing
and suggests its promising application as valuable and novel indigenous leads in the food and pharmaceutical industries. To the best of our knowledge, this is the first-ever investigatory report on the systematic phytochemical and therapeutic examination of S. pubescens fruit essential oil.
Binding Sites of Anticancer Drugs on Human Serum Albumin (HSA): A
Review
Authors: Molaei Pejman , Mahaki Hanie , Manoochehri Hamed , Tanzadehpanah Hamid
Published: April 2022

Background:

To recognize the action of pharmacologically approved anticancer drugs in
biological systems, information regarding its pharmacokinetics, such as its transport within the
plasma and delivery to its target site, is essential. In this study, we have tried to collect and present
complete information about how these drugs bind to human serum albumin (HSA) protein. HSA
functions as the main transport protein for an enormous variety of ligands in circulation and plays a
vital role in the efficacy, metabolism, distribution, and elimination of these agents.

Method:

Therefore, this study includes information about the quenching constant, the binding
constant obtained from Stern-Volmer and Hill equations, and molecular docking.

Results:

Molecular docking was carried out to detect the binding models of HSA–anticancer drugs
and the binding site of the drugs in HSA, which further revealed the contribution of amino acid
residues of HSA in the drug complex binding.

Conclusion:

This review study showed that site I of the protein located in domain II can be
considered the most critical binding site for anticancer drugs.
Antioxidation Abilities of Sesquiterpenoids from Curcuma aromatica
in vitro
Authors: Zhang Mi , Dai Weifeng , Wang Dong , Chen Chonglian
Published: April 2022

Aim and Objectives:

In our previous study, 21 sesquiterpenoids with different skeleton
types were isolated from the radix of Curcuma aromatica Salisb., a traditional Chinese medicine
used for treating depression and qi and blood stasis. C. aromatica enhanced PC12 cell viability upon
damage by H2O2. The aim of this study was to elucidate the antioxidation capability of these
sesquiterpenoids using a model of H2O2-induced PC12 cells and analyze the correlation between
their structure and bio-activity.

Materials and Methods:

PC12 cells were simultaneously treated with 400 μM H2O2 and sesquiterpenoid
compounds or vitamin E (used as a positive control) for 24 h. The activities of GSH-Px,
LDH, CAT, and SOD were detected by ELISA kits. The reactive oxygen species (ROS) level in
the cells was determined by the fluorescence probe DCFH-DA. [Ca2+]i was detected based on the
Fluo 2-AM fluorescence labeling assay. The structures of sesquiterpenoids were featured with 41
selected molecular descriptors, and the relationship between active parameters and structural features
was determined by the partial least squares (PLS) analysis.

Results:

All twenty-one sesquiterpenoids from the radix of C. aromatica increased the activities of
GSH-Px, CAT, and SOD, and decreased the LDH leakage, and levels of ROS level and [Ca2+]i to
different degrees. Some relationships were observed between the molecular descriptors featured by
the sesquiterpenoids and GSH-Px, CAT, SOD, LDH, ROS, and [Ca2+]i by PLS analysis.

Conclusions:

Twenty-one sesquiterpenoids showed different antioxidation abilities as measured by
a model of H2O2-induced PC12 cells. Five molecular descriptors were positively correlated with
GSH-Px, CAT, SOD, and were negatively correlated with LDH and [Ca2+].
Silk Derived Fe/N-Doping Porous Carbon Nanosheets for Chloramphenicol Electrochemical Detection
Authors: Chang Wenzhuo , Zhu Yongxi , Ma Yongjun , Zheng Zhixiang , Wang Chunming
Published: April 2022

Background:

The use of modified electrochemical sensors is essential for the detection of antibiotic
drug abuse. The main objective of this article is to develop a silk-derived carbon material for the modification
of pyrolytic graphite electrodes (PGE) for the sensitive detection of chloramphenicol (CAP).

Methods:

We proposed a pyrolysis synthesis of porous carbon nanosheets (Fe-Silk PNC) using silk as a
precursor. Properties of carbon nanosheets had been improved by the Fe-Nx atoms doping, which was
attributed to the β-sheet structures and amino-group-rich chemical structures of silk fibroin, and this material
has been used to modify the pyrolytic graphite electrode (PGE) for the electrochemical determination
of CAP. Scanning electron microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FT-IR)
were used to determine the morphology and properties of Fe-Silk PNC surface. In the electrochemical
determination, cyclic voltammetry (CV) showed a superior current response while bare electrode performed
an inferior result. In addition, different scan rate, pH, accumulation time and accumulation potential
were carefully optimized, which proved that this material is appropriate for CAP detection. Finally,
differential pulse voltammetry (DPV) method was used for quantitative measurements.

Result:

In this study, DPV determination of CAP showed the linear relationship with increasing concentration
ranged from 1 to 200 μM, and the low detection limit was 0.57 μM (S/N = 3). SEM and FT-IR
results further demonstrated the N-doped carbon nanomaterials were successfully synthesized. With excellent
sensing performance achieved, the practicability of the sensor has been evaluated to detect CAP in
chicken, shrimps and fish.

Conclusion:

In summary, a silk derived biomass porous carbon nanomaterial Fe-Silk PNC was simply
fabricated and used as a novel electrode material. This kind of novel Fe-Silk PNC modified electrode
exhibited excellent sensitivity, anti-interference ability, repeatability, wide linear rang, and was successfully
used for determination of CAP in real samples. Therefore, the biomass derived nanomaterial is expected
to be used in new sensing materials.
Recensie van: Daens / Frans-Jos Verdoodt
Authors: Van Campenhout Nico
Published: April 2022

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Snel weer op weg. Het verleden van de Vlaamse Automobilistenbond (VAB)
Authors: Bossaert Sophie
Published: April 2022

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Emmanuel de Boms burgerlijke ongehoorzaamheid en de vernederlandsing van de Burgerwacht
Authors: Ceustermans Chris
Published: April 2022

Tot de Eerste Wereldoorlog was de Bur-gerwacht in België een van de symbolen bij uitstek van de jonge natie. Zoals in andere maatschappelijke domeinen, leidde de overheersing van de Franse taal er tot toenemende spanningen. In vergelijking met het gerecht en onderwijs, duurde het erg lang tot de Nederlandstaligen in de Burgerwacht taalrechten verkregen. De rol van schrijver en Van Nu en Straks’er Emmanuel de Bom (1868-1953) is daarbij weinig gekend. De Bom lag nochtans na een actie van burgerlijke ongehoorzaamheid en gevangenisstraf aan de basis van vernederlandsingscampagnes van de Burgerwacht in 1895-1896. Op basis van De Boms persoonlijk archief en via krantenberichten reconstrueren we de in die tijd geruchtmakende zaak ‘De Bom versus Burgerwacht’. Daaruit blijkt dat de anarchistische actie van De Bom en de daaropvolgende publieke campagne de weg bereidden voor de ‘taalwet Heuvelmans’ van 1897 inzake de Burgerwacht.__________
Emmanuel de Bom’s civil disobedience and the Dutchification of the Civil GuardUntil the First World War, the ‘Burgerwacht’ [Civil Guard] in Belgium was one of the young nation’s exemplary symbols. As in other societal spheres however, the predominance of the French language resulted in heightened tensions, and compared to justice and education, it took a long time before Dutch speakers acquired linguistic rights in the Civil Guard. The role of the writer and member of the journal Van Nu en Straks [Of Now and Later] Emmanuel de Bom (1868-1953) in this process has largely remained unknown, even though his action of civil disobedience and subsequent imprisonment gave the impetus for the campaigns to demand for the Dutchification of the Civil Guard in 1895-1896. Using De Bom’s personal archive and newspaper articles, we will reconstruct the then notorious case of ‘De Bom versus the Civil Guard’. It will become clear how De Bom’s anarchist action and the subsequent public campaign lay the groundwork for the 1897 ‘Language Law Heuvelmans’ that addressed the issue of the Civil Guard.
Recensie van 1942. Het jaar van de stilte / Herman Van Goethem
Authors: Stynen Andreas
Published: April 2022

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Juryverslag Pil-van Gastelprijs voor Geschiedenis 2019
Authors: De Smedt Helma
Published: April 2022

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Влияние водорода на электрические и фотоэлектрические свойства тонкопленочных структур InP/Pd, полученных золь-гель методом
Authors: Гребенщикова Е.А. , Шутаев В.А. , Матвеев В.А. , Губанова Н.Н. , Шилова О.А. , Яковлев Ю.П.
Published: April 2022

The current-voltage characteristics and photoelectric properties of semiconductor structures containing Pd nanoparticles in thin films synthesized by the sol-gel method on an n-InP substrate have been investigated. The experimental results show that in presence of hydrogen the cut-off voltage changes. The photovoltage and photocurrent upon illumination of the structure with an LED (λ = 0.9 μm) and pulsed exposure to hydrogen change, that was observed earlier for hydrogen-sensitive Pd/n-InP Schottky diodes. The prospects of using the structures under study as a sensitive element for hydrogen sensor are discussed.
Микромеханизм многомасштабного динамического разрушения
Authors: Мещеряков Ю.И. , Диваков А.К. , Жигачева Н.И. , Коновалов Г.В. , Нечунаев А.Ф.
Published: April 2022

The shock propagation in non-uniform medium is studied theoretically and experimentally. A set of experiments on shock loading of high-strength low-alloyed AB2 steel is performed. The "trigger" mechanism for switching the dynamic fracture from one scale to another is shown to be the resonance interaction of plastic flow oscillations and mesoscopic structural elements. There is a threshold strain rate at which the defect (decrease) of mass velocity at the plateau of compressive pulse increases abruptly. Under strain rates higher threshold value, a multitude of short transcrystalline cracks is formed, which results in decay of shock wave,
Повышение эффективности фотопьезоэлектрического индуцирования акустических волн в полуизолирующих монокристаллах арсенида галлия
Authors: Митрохин В.И. , Кривенко Н.Н. , Логинов В.А. , Железный С.В.
Published: April 2022

The work is devoted to the analysis of the influence of acoustic losses on the efficiency of inducing resonant acoustic waves in single-crystal gallium arsenide plastids using infrared light pulses. It is established that the amplitude of the excited mechanical vibrations depends on the magnitude and position of the internal friction in the crystal on the temperature scale due to acousto-electronic relaxation. Recommendations on the choice of the element of the alloying admixture of gallium arsenide are formulated.
Identification of a Novel c.3080delC JAG1 Gene Mutation Associated With Alagille Syndrome: Whole Exome Sequencing
Authors: Panwar Deepak , Lal Vandana , Thatai Atul
Published: April 2022

Background

Alagille syndrome is an autosomal dominant disorder associated with variable clinical phenotypic features including cholestasis, congenital heart defects, vertebral defects, and dysmorphic facies.

Objective

Whole exome sequencing (WES) has become technically feasible due to the recent advances in next-generation sequencing technologies, therefore offering new possibilities for mutations or genes identification.

Methods

WES was used to identify pathogenic variants, which may have significant prognostic implications for patients’ clinical presentation of the proband. In this paper, we have uncovered a novel JAGGED1 gene (JAG1) mutation associated with Alagille syndrome in a 5-year-old girl presented with conjugated hyperbilirubinemia and infantile cholestasis.

Results

The exome sequencing analysis revealed the presence of a novel JAG1 heterozygous c.3080delC variant in exon 25. The detected variant introduced a stop codon (p.P1027RfsTer9) in the gene sequence, encoding a truncated protein. Our exome observations were confirmed through Sanger sequencing as well.

Conclusions

Here, we report a case of a patient diagnosed with Alagille syndrome, conjugated hyperbilirubinemia, and infantile cholestasis, with emphasis on its association with the detection of the novel JAG1 mutation, thereby establishing the genetic diagnosis of the disease.
Emergency Telemedicine Mobile Ultrasounds Using a 5G-Enabled Application: Development and Usability Study
Authors: Berlet Maximilian , Vogel Thomas , Gharba Mohamed , Eichinger Joseph , Schulz Egon , Friess Helmut , Wilhelm Dirk , Ostler Daniel , Kranzfelder Michael
Published: April 2022

Background

Digitalization affects almost every aspect of modern daily life, including a growing number of health care services along with telemedicine applications. Fifth-generation (5G) mobile communication technology has the potential to meet the requirements for this digitalized future with high bandwidths (10 GB/s), low latency (<1 ms), and high quality of service, enabling wireless real-time data transmission in telemedical emergency health care applications.

Objective

The aim of this study is the development and clinical evaluation of a 5G usability test framework enabling preclinical diagnostics with mobile ultrasound using 5G network technology.

Methods

A bidirectional audio-video data transmission between the ambulance car and hospital was established, combining both 5G-radio and -core network parts. Besides technical performance evaluations, a medical assessment of transferred ultrasound image quality and transmission latency was examined.

Results

Telemedical and clinical application properties of the ultrasound probe were rated 1 (very good) to 2 (good; on a 6 -point Likert scale rated by 20 survey participants). The 5G field test revealed an average end-to-end round trip latency of 10 milliseconds. The measured average throughput for the ultrasound image traffic was 4 Mbps and for the video stream 12 Mbps. Traffic saturation revealed a lower video quality and a slower video stream. Without core slicing, the throughput for the video application was reduced to 8 Mbps. The deployment of core network slicing facilitated quality and latency recovery.

Conclusions

Bidirectional data transmission between ambulance car and remote hospital site was successfully established through the 5G network, facilitating sending/receiving data and measurements from both applications (ultrasound unit and video streaming). Core slicing was implemented for a better user experience. Clinical evaluation of the telemedical transmission and applicability of the ultrasound probe was consistently positive.
The Impact of Perioperative Remote Patient Monitoring on Clinical Staff Workflows: Scoping Review
Authors: León Maria Alejandra , Pannunzio Valeria , Kleinsmann Maaike
Published: April 2022

Background

Remote patient monitoring (RPM) interventions are being increasingly implemented in health care environments, given their benefits for different stakeholders. However, the effects of these interventions on the workflow of clinical staff are not always considered in RPM research and practice.

Objective

This review explored how contemporary RPM interventions affect clinical staff and their workflows in perioperative settings.

Methods

We conducted a scoping review of recent articles reporting the impact of RPM interventions implemented in perioperative settings on clinical staff and their workflow. The databases accessed were Embase and PubMed. A qualitative analysis was performed to identify the main problems and advantages that RPM brings to staff, in addition to the approaches taken to evaluate the impact of those interventions. Different themes were identified in terms of the challenges of RPM for clinical staff as well as in terms of benefits, risk-reduction strategies, and methods for measuring the impact of these interventions on the workflow of clinical staff.

Results

A total of 1063 papers were found during the initial search, of which 21 (1.98%) met the inclusion criteria. Of the 21 included papers, 15 (71%) focused on evaluating new RPM systems, 4 (19%) focused on existing systems, and 2 (10%) were reviews.

Conclusions

The reviewed literature shows that the impact on staff work experience is a crucial factor to consider when developing and implementing RPM interventions in perioperative settings. However, we noticed both underdevelopment and lack of standardization in the methods for assessing the impact of these interventions on clinical staff and their workflow. On the basis of the reviewed literature, we recommend the development of more robust methods for evaluating the impact of RPM interventions on staff experience in perioperative care; the adoption of a stronger focus on transition management when introducing these interventions in clinical practice; and the inclusion of longer periods of assessment, including the evaluation of long-term goals.
Construction of a Linked Data Set of COVID-19 Knowledge Graphs: Development and Applications
Authors: Wang Haofen , Du Huifang , Qi Guilin , Chen Huajun , Hu Wei , Chen Zhuo
Published: April 2022

Background

With the continuous spread of COVID-19, information about the worldwide pandemic is exploding. Therefore, it is necessary and significant to organize such a large amount of information. As the key branch of artificial intelligence, a knowledge graph (KG) is helpful to structure, reason, and understand data.

Objective

To improve the utilization value of the information and effectively aid researchers to combat COVID-19, we have constructed and successively released a unified linked data set named OpenKG-COVID19, which is one of the largest existing KGs related to COVID-19. OpenKG-COVID19 includes 10 interlinked COVID-19 subgraphs covering the topics of encyclopedia, concept, medical, research, event, health, epidemiology, goods, prevention, and character.

Methods

In this paper, we introduce the key techniques exploited in building COVID-19 KGs in a top-down manner. First, the schema of the modeling process for each KG in OpenKG-COVID19 is described. Second, we propose different methods for extracting knowledge from open government sites, professional texts, public domain–specific sources, and public encyclopedia sites. The curated 10 COVID-19 KGs are further linked together at both the schema and data levels. In addition, we present the naming convention for OpenKG-COVID19.

Results

OpenKG-COVID19 has more than 2572 concepts, 329,600 entities, 513 properties, and 2,687,329 facts, and the data set will be updated continuously. Each COVID-19 KG was evaluated, and the average precision was found to be above 93%. We have developed search and browse interfaces and a SPARQL endpoint to improve user access. Possible intelligent applications based on OpenKG-COVID19 for further development are also described.

Conclusions

A KG is useful for intelligent question-answering, semantic searches, recommendation systems, visualization analysis, and decision-making support. Research related to COVID-19, biomedicine, and many other communities can benefit from OpenKG-COVID19. Furthermore, the 10 KGs will be continuously updated to ensure that the public will have access to sufficient and up-to-date knowledge.
Distinguishing Admissions Specifically for COVID-19 From Incidental SARS-CoV-2 Admissions: National Retrospective Electronic Health Record Study
Authors: Klann Jeffrey G , Strasser Zachary H , Hutch Meghan R , Kennedy Chris J , Marwaha Jayson S , Morris Michele , Samayamuthu Malarkodi Jebathilagam , Pfaff Ashley C , Estiri Hossein , South Andrew M , Weber Griffin M , Yuan William , Avillach Paul , Wagholikar Kavishwar B , Luo Yuan ,   The Consortium for Clinical Characterization of COVID-19 by EHR (4CE), Omenn Gilbert S , Visweswaran Shyam , Holmes John H , Xia Zongqi , Brat Gabriel A , Murphy Shawn N
Published: April 2022

Background

Admissions are generally classified as COVID-19 hospitalizations if the patient has a positive SARS-CoV-2 polymerase chain reaction (PCR) test. However, because 35% of SARS-CoV-2 infections are asymptomatic, patients admitted for unrelated indications with an incidentally positive test could be misclassified as a COVID-19 hospitalization. Electronic health record (EHR)–based studies have been unable to distinguish between a hospitalization specifically for COVID-19 versus an incidental SARS-CoV-2 hospitalization. Although the need to improve classification of COVID-19 versus incidental SARS-CoV-2 is well understood, the magnitude of the problems has only been characterized in small, single-center studies. Furthermore, there have been no peer-reviewed studies evaluating methods for improving classification.

Objective

The aims of this study are to, first, quantify the frequency of incidental hospitalizations over the first 15 months of the pandemic in multiple hospital systems in the United States and, second, to apply electronic phenotyping techniques to automatically improve COVID-19 hospitalization classification.

Methods

From a retrospective EHR-based cohort in 4 US health care systems in Massachusetts, Pennsylvania, and Illinois, a random sample of 1123 SARS-CoV-2 PCR-positive patients hospitalized from March 2020 to August 2021 was manually chart-reviewed and classified as “admitted with COVID-19” (incidental) versus specifically admitted for COVID-19 (“for COVID-19”). EHR-based phenotyping was used to find feature sets to filter out incidental admissions.

Results

EHR-based phenotyped feature sets filtered out incidental admissions, which occurred in an average of 26% of hospitalizations (although this varied widely over time, from 0% to 75%). The top site-specific feature sets had 79%-99% specificity with 62%-75% sensitivity, while the best-performing across-site feature sets had 71%-94% specificity with 69%-81% sensitivity.

Conclusions

A large proportion of SARS-CoV-2 PCR-positive admissions were incidental. Straightforward EHR-based phenotypes differentiated admissions, which is important to assure accurate public health reporting and research.
Impacto de las políticas de calidad en los procesos educativos de la educación superior*
Authors: Silva Laya Marisol
Published: April 2022

Se analiza cómo las políticas de calidad educativa –atención integral al estudiante y enfoques centrados en el aprendizaje– son acogidas al interior del sistema de educación superior, en qué medida brindan orientación a las instituciones que lo conforman, cómo se han traducido en acciones específicas dirigidas a mejorar los procesos educativos y cuáles son sus alcances y vacíos. Para ello, se hace un análisis de los objetivos y metas del PRONAE 2001-2006 y se revisa de manera general el comportamiento del sector universitario en torno a las metas que propuso. Adicionalmente, se examina la operación de las políticas en la Universidad de Occidente. Se concluye que, a pesar de la movilización y despliegue de ciertas iniciativas institucionales, aún falta una comprensión cabal y acciones efectivas para poner en marcha las políticas que buscan impulsar nuevos enfoques y estrategias educativas que incrementen la calidad académica.
Design of Laparoscopic Morcellator Endo-Surgery Instrument
Authors: Shende Dr. Pankaj , Siddique Wasim Ahamed , Dhotkar Sanket , Bopate Sumit , Chandel Aishwarya
Published: April 2022

Abstract: The main report is based on Morcellators which is surgical tool that doctors use to cut bigger chunks of tissue into smaller once, usually during laparoscopic surgery we intend to built prototype of low-cost morcellators using dc motor controlling .By studying techniques of pwm and various other morcellators. Nowdays the cost of abdomenal surgery is high the main reason behind this is the surgical cost involve in this process.The machinery is mostly imported from German countries as a result the cost is high so we intended to build an morcellator which is low in cost. Keywords: morcellars, laparoscopy, surgey, Atmega328p.
Fake Job Detection Using Machine Learning
Authors: Khandagale Priya , Utekar Akshata , Dhonde Anushka , Karve Prof. S. S.
Published: April 2022

Abstract: The research proposes an automated solution based on machine learning-based classification approaches to prevent fraudulent job postings on the internet. Many organizations these days like to list their job openings online so that job seekers may access them quickly and simply. However, this could be a form of scam perpetrated by con artists who offer job seekers work in exchange for money. Many people are duped by this fraud and lose a lot of money as a result. We can determine which job postings are fraudulent and which are not by conducting an exploratory data analysis on the data and using the insights gained. In order to detect bogus posts, a machine learning approach is used, which employs numerous categorization algorithms. The system would train the model to classify jobs as authentic or false based on previous data of bogus and legitimate job postings. To start, supervised learning algorithms as classification techniques can be considered to handle the challenge of recognizing scammers on job postings. It will employ two or more machine learning algorithms, selecting the one that yields the highest accuracy score in the prediction of whether a job advertising headline is genuine or not. Keywords: Fake Job, Online Recruitment, Machine Learning, Ensemble Approach.
Car Service Slot Booking System
Authors: Reddy Chaganti Sandeep , Savant Dr. Preeti
Published: April 2022

Abstract: The purpose of implementing this application was for users to book a slot for car servicing by using the car bath app. The automobile Car Bath industry is additionally growing staggeringly and automobile owners favor requesting cleanup services through their mobile devices. To make the automotive wash programming computer code additional reliable, distinctive panels are developed for all users. The service provider's panel advantages to showcasing and automatizing the entire automotive particularization and washing services business online are viable in a very single click. The options of our appointment booking computer code have created the net automotive wash system sturdy. easy showing the services, booking the appointments 24/7, the choice of fixing the service packages, on-line transactions, etc. area unit a number of the main characteristics to spice up productivity. This application is simple and users will book the automotive service squeeze the automotive Car Bath app. This application mostly saves time and human work free. Users can book the services at anytime and anywhere. This type of service is now growing very rapidly and the booking system is used very easily and more accessible. Now every ware there is all online services and just one click away. The car Bath app is allowed to book the slot for car service. By using this app customers can book the service at their flexible time. It's a user-friendly application. In this application customer, data will store very securely. By using this application customers can save time and energy. By using this app, we can book any type of vehicle for service. Currently, technology is very fast. People want to measure an expensive life with minimum physical work. This application is an android app that will be run on any android compatible tablet and portable. The app can alter any automobile user to book an appointment for automobile service. Index Terms: Car bath service, android application, booking, and user-friendly.
A Research on Placement Management System
Authors: Banu Alfiya , S. K Dr. Manju Bargavi
Published: April 2022

Abstract: The project is to create an application for a college's placement management system, which is mostly web- based. It's a web-based application built on the Windows platform for the college'splacement department to save informationabout its students in a database for firms to use in their recruitment process if they have the necessary login credentials. All of the necessary information about the pupils is stored in the system. The system saves all of the students' personal information as well as their technical skills, which are needed for a CV to be sent to an employer. The system can be used by institutions to manage student information and placement details.Students should be able to access their accounts and upload their work. This project helps students to keep track of their personaland academic information. It saves time by decreasing manual labor and reducing theamount of paper used. Keywords: Authorization, Admin, Student, TPO, Web development.
Hyperledger Fabric Implementation for a Transparent Food Product Supply Chain
Authors: H Srikanth , K Anagha , Rengarajan Dr. A. , N Prof. Priya
Published: April 2022

Abstract: Blockchain technology came into existence because of bitcoin and has seen an extensive set of applications in recent times. In the last few years, numerous projects have been taken up to make use of the efficient features provided by this technology. The main focus of the blockchain is to maintain trust among the users. Farmers of the country are facing huge issues because of the corruption in the supply chain involved due to which they are not getting the proper market price for the goods produced. With the help of the Blockchain we can make the contract transparent and make the payment systems automatic which in return will help the economic situation of the farmers and reduce corruption in the system. Keywords: blockchain, supply chain, Hyperledger, agricultural, transparency
Savvy Gadget for Visually Challenged
Authors: S Swapna , J Geetha Ramani , M S Roshini , N Uma , P A Yazhini
Published: April 2022

Abstract: This article involves a gadget that is very useful for the visually challenged people. The main advantage of this project is it is cost effective and easy to use. 30 million individuals are for all time visually impaired and 285 billion are visually challenged, as indicated by the WHO. At the point when you consider them, you will understand very well that without the guide of others they mightn't walk to at any point arrive at your objective one needs to request headings. During their day to day routines, they need to confront more difficulties. The visually impaired handle is more secure for an individual to walk. The gadget we made detects the thing before the individual and gives the user a vibration response. Furthermore, the person can go without uneasiness. This application is the best answer for take care of the issues. Keywords: Visually challenged, walking stick, arduino, sensor technology, blind.
Multi-objective Heat Sink Optimization by Using Taguchi Method
Authors: Shinde Anil , Mane Ajit , Palake Adinath , Mohite Balkrushan , Khot Akash , Vhatkar Tirupati , Kharavate Ankur
Published: April 2022

Abstract: Nowadays, with the rapid growth in electronic devices, compact and efficient heat sinks are required in day-to-day life. That’s why it's need to be use optimized heat sinks. The excess heat generated causes damage in different parts also generates major problems in the system. So, in this work three-dimensional square channel of copper material is used to study heat transfer coefficient and pressure drop. The comparative numerical analysis of thermal management system different parameter like coolant fluid, inlet velocity of fluid, shape of obstacles, aspect ratio of obstacles and number of obstacles is presented in this paper. Analysis and optimization of the heat sink are done by three different methods i.e., experimental, analytical, and simulation. In this work analytical and simulation method is used for the optimization of a heat sink. There are many software’s are available for analysis and optimization, by using the “COMSOL Multi-physics software” we optimize multi objectives heat sink. After analytical and numerical analysis, to optimize best result Taguchi method is preferred, for that MINITAB software is used. Keywords: Heat transfer coefficient, pressure drop, micro heat sink, Taguchi method, Analysis, optimization, COMSOL Multiphysics software, MINITAB software.
BeCareful: Personal Safety Application with Scream Detection
Authors: Bandre Ajit , Chinchkar Snehal , Zope Ruchira , Jadhav Sheetal
Published: April 2022

Abstract: It's turning more and more unsafe for a person to travel alone in the dark. the foremost effective because of avoiding being a victim of a violent crime is to identify and switch resources to help you out of unsafe things. whether or not or not you are in peril or get separated from friends throughout the night and do not understand the thanks to getting home, having facilitated at hand once we want it is a relief. thence we tend to gift BeCareful, a non-public safety application. BeCareful means providing protection, saving, shielding or defending yourself from danger. This application tracks things of the user through GPS and permits a non- public to at once request for facilitating in black things with merely a regulator. It transmits the user’s location And AN alert message to the positive and registered contacts once the user feels unsafe. These contacts can track the user’s location in real-time and provide the desired facility. Keywords: GPS, Google Maps, SOS messages, Google API, Firebase.
Optimal synthesis into fixed XX interactions
Authors: Peterson Eric C. , Bishop Lev S. , Javadi-Abhari Ali
Published: April 2022

We describe an optimal procedure, as well as its efficient software implementation, for exact and approximate synthesis of two-qubit unitary operations into any prescribed discrete family of XX-type interactions and local gates. This arises from the analysis and manipulation of certain polyhedral subsets of the space of canonical gates. Using this, we analyze which small sets of XX-type interactions cause the greatest improvement in expected infidelity under experimentally-motivated error models. For the exact circuit synthesis of Haar-randomly selected two-qubit operations, we find an improvement in estimated infidelity by 31.4% when including alongside CX its square- and cube-roots, near to the optimal limit of 36.9% obtained by including all fractional applications of CX.
Eigenstate entanglement in integrable collective spin models
Authors: Kumari Meenu , Alhambra Álvaro M.
Published: April 2022

The average entanglement entropy (EE) of the energy eigenstates in non-vanishing partitions has been recently proposed as a diagnostic of integrability in quantum many-body systems. For it to be a faithful characterization of quantum integrability, it should distinguish quantum systems with a well-defined classical limit in the same way as the unequivocal classical integrability criteria. We examine the proposed diagnostic in the class of collective spin models characterized by permutation symmetry in the spins. The well-known Lipkin-Meshov-Glick (LMG) model is a paradigmatic integrable system in this class with a well-defined classical limit. Thus, this model is an excellent testbed for examining quantum integrability diagnostics. First, we calculate analytically the average EE of the Dicke basis{|j,m⟩}m=−jjin any non-vanishing bipartition, and show that in the thermodynamic limit, it converges to1/2of the maximal EE in the corresponding bipartition. Using finite-size scaling, we numerically demonstrate that the aforementioned average EE in the thermodynamic limit is universal for all parameter values of the LMG model. Our analysis illustrates how a value of the average EE far away from the maximal in the thermodynamic limit could be a signature of integrability.
A new direction for calculating the strength of bent reinforced concrete elements along inclined sections with an example of calculating an experimental beam
Authors: Starishko Ivan N.
Published: April 2022

The reliability of the operation of structures and structures as a whole Received: March 25, 2021 during their operation significantly depends on many factors that are not always Revised: May 27, 2021 fully taken into account by the calculation. One of the reasons for this may be a narrow Accepted: June 3, 2021 focus of many experimental researches, the results of which are taken for guidance in the development of the theory of calculation. Sometimes the calculation theories are not at all substantiated by experimental research. The experimental research methodology will give a positive effect for the development of a reliable theory for the calculation of bent reinforced concrete elements along inclined sections only when it combines the whole variety of influence of the main factors on the operation of the investigated elements, including the type of loads applied during testing - evenly distributed or focused, with deep analysis of the obtained results. In the proposed theory of strength calculation for inclined sections of bent reinforced concrete elements the relationship in the development of the stress-strain state under the action of a load both in normal and inclined sections to the longitudinal axis of the elements, up to the destruction of beams, obtained as a result of experimental theoretical research, is used. This ensures a close coincidence of the experimental and calculated data, increases the reliability, durability and economic efficiency of structures during their operation.
Research of the accessibility of Russian universities websites for persons with visual disabilities
Authors: Pudich Alexander S. , Grif Mikhail G. , Bakaev Maxim A.
Published: April 2022

Problem statement. Nowadays the demand for university websites has increased. According to the law, versions for visually impaired have been introduced on educational sites in Russia. The research objective is to evaluate accessibility of sites and quality of versions for visually impaired (mainly in an automatic way), and to identify the best way to implement such solutions and to create accessible sites in general. Methodology. A software system for collecting metrics from websites in two versions - a normal and for visually impaired users - has been developed. Quantitative metrics based on the HTML code of home- pages and visual analysis of homepages screenshots are compared. Metrics were also received by manual testing. Results. Data from 571 universities websites with open access to files was observed. The correlation analysis of metrics was carried out. The quality of versions for visually impaired was assessed, recommendations were made for technical implementation and a standard set of settings for panel of version for visually impaired users. Statistics of used ready-made solutions, as well as website development tools, was collected. Conclusion. An idea has appeared about current issues in the field of accessibility of educational sites in Russia, and about what can be used to evaluate and developing of accessible sites. The recommendations can be used as one of the guidelines for developing or checking versions for visually impaired.
Penularan Patogen CVPD Melalui Vektor D. citri Stadia Imago dan Nimfa pada Bibit Jeruk Rough Lemon dan Siem
Authors: Marlina Marlina , Mapegau Mapegau , Hayati Islah
Published: April 2022

Penelitian ini bertujuanuntuk mempelajari penularan penyakit CVPD  melaluivektor Diaphorina citri  stadia imago dan nimfa pada jeruk Siem dan Rough Lemon. Percobaan dilaksanakan dengan menggunakan Rancangan Acak Lengkap pola faktorial dua faktor.Faktor Kultivar  Jeruk (Rough  Lemon, dan Siem)  diletakkan  sebagai  faktor  pertama,  sedangkan  fakor   stadia  vektor (Nimfa, dan Imago) sebagai faktor kedua. Empat kombinasi perlakukan masing-masing diulang 5 kali.Tiap perlakuan terdiri dari 2 pot tanaman percobaan.Data respons tanaman terhadap penyakit CVPD yang diinokulast melalul vektor D.citri berbeda stadia diperoleh dengan menghitung:1) masa inkubasi yang diperoleh dengan cara mengamati lamanya waktu yang diperlukan tanaman sejak diinokulasi patogen sampai timbulnya gejala pertama;2) persentase daun klorosis yang diperoleh melalui pengamatan daun sampel yang diambil secara acak dan dihitung jumlah daun yang klorosis dari jumlah daun tanaman sampel, 3) persentase cabang yang bergejala, diperoleh dengan menghitung jumlah cabang yang bergejala dari jumlah cabang seluruhnya per tanaman tiap perlakuan.Hasil penelitian menunjukkan bahwa masa inkubasi penyakit CVPD, persentase daun klorosis, dan persentase daun bergejala lebih cepat dan lebih tinggi pada jeruk Siem dibandingkan dengan pada jeruk Rough Lemon, baik yang ditulari melalui inokulasi dengan D. citri stadia imago maupun stadia nimfa. Tetapi penularan melalui inokulasi D. citri pada stadio imago lebih cepat memunculkan masa inkubasi, persentase daun, klorosis, dan persentase cabang bergejala lebih tinggi dibandingkan dengan stadia nimfa. Jeruk siem dan penularan penyakit CVPD melalui D. citri stadia nimfa dapat dijadikan cara deteksi dini penyakit CVPD pada jeruk
DUKUNGAN SOSIAL DALAM QS. AD-DHUHA DAN QS. AL-INSYIRAH
Authors: Arlotas Rena Kinnara
Published: April 2022

Introduction Al-Quran is a guide to human life, include a balance between physical and mind, worship and self ability, relationships between people, and so on. Regarding guidance in human relations, the Koran has also given us instructions on how to provide social assistance for others who need it. This can be seen in QS. Ad-Dhuha and Al-Insyirah.Objective This research supports to see how social support is contained in QS. Ad-Dhuha and Al-Insyirah.The results of this research is social support contained in the QS. Ad-Dhuha and Al-Insyirah consist of emotional support, network support, esteem support, instrumental support, and information support. The benefits received by Rasulullah SAW after receiving this support are psychological well being, calm, and the burden becomes lighter. Rasulullah SAW also provides social support to others, especially orphans and beggar, and always give thanks to Allah SWT.Recomendatian So, we always believe in Allah SWT, always be grateful for all the support and gifts that He has given and we also always provide social support for others.
Keyword: Social support, QS Ad-Dhuha, QS. AL-Insyirah
ABSTRAK
Pendahuluan Al-Quran adalah petunjuk hidup manusia yang meliputi keseimbangan antara lahir dan batin, ibadah dan kemampuan diri, hubungan antar manusia, dan sebagainya. Mengenai petunjuk dalam hubungan antar manusia, Al-Quran juga telah memberikan petunjuk bagi kita mengenai bagaimana memberikan dukungan sosial bagi orang lain yang membutuhkannya. Hal ini antara lain terlihat dalam QS. Ad-Dhuha dan Al-Insyirah.
Tujuan Penelitian ini bertujuan untuk melihat bagaimana dukungan sosial yang terkandung dalam QS. Ad-Dhuha dan Al-Insyirah.
Hasil Dari hasil penelitian diketahui bahwa dukungan sosial yang terkandung dalam QS. Ad-Dhuha dan Al-Insyirah adalah berupa dukungan emosional (emotional support), dukungan jaringan (network support), dukungan penghargaan (esteem support), dukungan instrumental (tangible aid), dan dukungan informasi (informational support). Manfaat yang dirasakan Rasulullah SAW setelah mendapat dukungan tersebut adalah meningkatnya psychological well being, hatinya menjadi tenang dan lapang, serta bebannya menjadi terasa lebih ringan. Rasulullah SAW juga disuruh untuk memberikan dukungan sosial kepada orang lain, khususnya anak yatim dan orang yang meminta minta, serta senantiasa bersyukur pada Allah SWT.
Saran Gambaran ini juga menjadi tuntunan bagi kita untuk selalu beriman kepada Allah SWT, senantiasa bersyukur atas segala dukungan dan karunia yang telah diberikan-Nya dan hendaknya kita juga senantiasa memberikan dukungan sosial bagi orang lain.
Kata Kunci: Dukungan sosial, QS Ad-Dhuha, QS. AL-Insyirah
A Religião e as funções institucionais do Estado
Authors: De Campos Echeverria João Paulo
Published: April 2022

Trata-se de estudo formulado no sentido de identificar o poder do exercício da religiosidade no espaço público e no fomento às políticas públicas, especialmente a partir da perspectiva de que a religião compete com o Estado na determinação da conduta dos indivíduos em sociedade. O estudo perpassa uma noção conceitual de Estado, assim como trabalha a dinâmica das instituições públicas e das políticas públicas oferecidas pelo Estado, para concluir que a formulação histórica (e religiosa) da sociedade não pode ser ignorada quando da criação de instrumentos normativos por parte do Estado.
Long time well-posedness of 2-D MHD boundary layer equation without resistivity
Authors: Chen Dongxiang , Li Xiaoli
Published: April 2022

This paper investigates the long time well-posedness of 2-D MHD boundary
layer equation without resistivity. It is proved that if the initial
data satisfies \begin{align*}
\|(u_0,h_0-1)\|_{H_{\mu}^{3,0}}+\|(u_0,h_0-1)\|_{H_{\mu}^{1,2}}+\|(u_0,h_0-1)\|_{H_{\mu}^{2,1}}\le
\varepsilon, \end{align*} then the life
span of the solution is at least of order
$\varepsilon^{-\f43}$.
On the low Mach number limit of the compressible \\ viscous micropolar fluid model
Authors: Yang Jianwei , Yang Xiao , Yang Jianqin , Shi Qihong
Published: April 2022

In this paper, we consider the low Mach number limit problem for the
compressible viscous micropolar fluid model based on the concept of
dissipative measure-valued solutions. We prove that the dissipative
measure-valued solutions of the compressible micropolar fluid model
converge to the smooth solution of the incompressible micropolar system
in the case of well-prepared initial data when the Mach number tends to
zero.