bluuebunny/crossref_metadata_2025 huggingface dataset:
Borneo Vortices in a warmer climate
Authors: Liang Ju , Catto Jennifer L. , Hawcroft Matthew K. , Tan Mou Leong , Hodges Kevin I. , Haywood James M.
Published: January 2023

Borneo Vortices (BVs) are weather systems that are responsible for devastating hydro-climatic extremes and significant losses of life and property in Southeast Asia. The typical resolution of most current climate models is insufficient to resolve these high-impact, synoptic-scale weather systems. Here, an ensemble of high-resolution models projects that future BVs may become less frequent and more stationary, driven by the weakening of the Northeast monsoon flow and associated cold surges across North Borneo. However, substantial increases in both the intensity and the total amount of precipitation from BVs are projected. Such changes are driven by the more humid and convectively unstable lower troposphere. As a result, the contribution of BVs to the accumulation of both total precipitation and extreme precipitation is projected to increase considerably in the vicinity of the southern South China Sea, making individual BVs more threatening to the adjacent coastal regions.
Towards precision radiation oncology: endocrine therapy response as a biomarker for personalization of breast radiotherapy
Authors: Udden S. M. Nashir , Baek GuemHee , Pandey Kamal , Vidal Chantal , Liu Yulun , Rahimi Asal S. , Kim D. Nathan , Nwachukwu Chika R. , Mani Ram S. , Alluri Prasanna G.
Published: January 2023

Targeted therapies, such as endocrine therapies (ET), can exert selective pressure on cancer cells and promote adaptations that confer treatment resistance. In this study, we show that ET resistance in breast cancer drives radiation resistance through reprogramming of DNA repair pathways. We also show that pharmacological bromodomain and extraterminal domain inhibition reverses pathological DNA repair reprogramming in ET-resistant breast tumors and overcomes resistance to radiation therapy.
The antidiabetic drug metformin aids bacteria in hijacking vitamin B12 from the environment through RcdA
Authors: Yao Luxia , Wang Yihan , Qin Shenlu , Zhu Shihao , Wu Lianfeng
Published: January 2023

Years of use of the antidiabetic drug metformin has long been associated with the risk of vitamin B12 (B12) deficiency in type 2 diabetes (T2D) patients, although the underlying mechanisms are unclear. Accumulating evidence has shown that metformin may exert beneficial effects by altering the metabolism of the gut microbiota, but whether it induces human B12 deficiency via modulation of bacterial activity remains poorly understood. Here, we show that both metformin and the other biguanide drug phenformin markedly elevate the accumulation of B12 in E. coli. By functional and genomic analysis, we demonstrate that both biguanides can significantly increase the expression of B12 transporter genes, and depletions of vital ones, such as tonB, nearly completely abolish the drugs’ effect on bacterial B12 accumulation. Via high-throughput screens in E. coli and C. elegans, we reveal that the TetR-type transcription factor RcdA is required for biguanide-mediated promotion of B12 accumulation and the expressions of B12 transporter genes in bacteria. Together, our study unveils that the antidiabetic drug metformin helps bacteria gather B12 from the environment by increasing the expressions of B12 transporter genes in an RcdA-dependent manner, which may theoretically reduce the B12 supply to T2D patients taking the drug over time.
Comparative transcriptomics reveals highly conserved regional programs between porcine and human colonic enteric nervous system
Authors: Li Tao , Morselli Marco , Su Trent , Million Mulugeta , Larauche Muriel , Pellegrini Matteo , Taché Yvette , Yuan Pu-Qing
Published: January 2023

The porcine gut is increasingly regarded as a useful translational model. The enteric nervous system in the colon coordinates diverse functions. However, knowledge of the molecular profiling of porcine enteric nerve system and its similarity to that of human is still lacking. We identified the distinct transcriptional programs associated with functional characteristics between inner submucosal and myenteric ganglia in porcine proximal and distal colon using bulk RNA and single-cell RNA sequencing. Comparative transcriptomics of myenteric ganglia in corresponding colonic regions of pig and human revealed highly conserved programs in porcine proximal and distal colon, which explained >96% of their transcriptomic responses to vagal nerve stimulation, suggesting that porcine proximal and distal colon could serve as predictors in translational studies. The conserved programs specific for inflammatory modulation were displayed in pigs with vagal nerve stimulation. This study provides a valuable transcriptomic resource for understanding of human colonic functions and neuromodulation using porcine model.
Murine breast cancers disorganize the liver transcriptome in a zonated manner
Authors: Vandenbon Alexis , Mizuno Rin , Konishi Riyo , Onishi Masaya , Masuda Kyoko , Kobayashi Yuka , Kawamoto Hiroshi , Suzuki Ayako , He Chenfeng , Nakamura Yuki , Kawaguchi Kosuke , Toi Masakazu , Shimizu Masahito , Tanaka Yasuhito , Suzuki Yutaka , Kawaoka Shinpei
Published: January 2023

The spatially organized gene expression program within the liver specifies hepatocyte functions according to their relative distances to the bloodstream (i.e., zonation), contributing to liver homeostasis. Despite the knowledge that solid cancers remotely disrupt liver homeostasis, it remains unexplored whether solid cancers affect liver zonation. Here, using spatial transcriptomics, we thoroughly investigate the abundance and zonation of hepatic genes in cancer-bearing mice. We find that breast cancers affect liver zonation in various distinct manners depending on biological pathways. Aspartate metabolism and triglyceride catabolic processes retain relatively intact zonation patterns, but the zonation of xenobiotic catabolic process genes exhibits a strong disruption. The acute phase response is induced in zonated manners. Furthermore, we demonstrate that breast cancers activate innate immune cells in particular neutrophils in distinct zonated manners, rather than in a uniform fashion within the liver. Collectively, breast cancers disorganize hepatic transcriptomes in zonated manners, thereby disrupting zonated functions of the liver.
Influence of air exposure on structural isomers of silver nanoparticles
Authors: Vernieres Jerome , Tarrat Nathalie , Lethbridge Sean , Watchorn-Rokutan Erica , Slater Thomas , Loffreda David , Palmer Richard E.
Published: January 2023

Up to date, the influence of ambient air exposure on the energetics and stability of silver clusters has rarely been investigated and compared to clusters in vacuum. Silver clusters up to 3000 atoms in size, on an amorphous carbon film, have been exposed to ambient air and investigated by atomic-resolution imaging in the aberration-corrected Scanning Transmission Electron Microscope. Ordered structures comprise more than half the population, the rest are amorphous. Here, we show that the most common ordered isomer structures is the icosahedron. These results contrast with the published behaviour of silver clusters protected from atmospheric exposure, where the predominant ordered isomer is face-centred cubic. We propose that the formation of surface oxide or sulphide species resulting from air exposure can account for this deviation in stable isomer. This interpretation is consistent with density functional theory calculations based on silver nanoclusters, in the size range 147-201 atoms, on which methanethiol molecules are adsorbed. An understanding of the effects of ambient exposure on the atomic structure and therefore functional properties of nanoparticles is highly relevant to their real-world performance and applications.
Self-transport of swimming bacteria is impaired by porous microstructure
Authors: Dehkharghani Amin , Waisbord Nicolas , Guasto Jeffrey S.
Published: January 2023

Motility is a fundamental survival strategy of bacteria to navigate porous environments, where they mediate essential biogeochemical processes in quiescent wetlands and sediments. However, a comprehensive understanding of the mechanisms regulating self-transport in the confined interstices of porous media is lacking, and determining the interactions between cells and surfaces of the solid matrix becomes paramount. Here, we precisely track the movement of bacteria (Magnetococcus marinus) through a series of microfluidic porous media with broadly varying geometries and show how successive scattering events from solid surfaces decorrelate cell motion. Ordered versus disordered media impact the cells’ motility over short ranges, but their large-scale transport properties are regulated by the cutoff of their persistent motility. An effective mean free path is established as the key geometrical parameter controlling cell transport, and we implement a theoretical model that universally predicts the effective cell diffusion for the diverse geometries studied here. These results aid in our understanding of the physical ecology of swimming cells, and their role in environmental and health hazards in stagnant porous media.
Multifunctionality of temperate alley-cropping agroforestry outperforms open cropland and grassland
Authors: Veldkamp Edzo , Schmidt Marcus , Markwitz Christian , Beule Lukas , Beuschel René , Biertümpfel Andrea , Bischel Xenia , Duan Xiaohong , Gerjets Rowena , Göbel Leonie , Graß Rüdiger , Guerra Victor , Heinlein Florian , Komainda Martin , Langhof Maren , Luo Jie , Potthoff Martin , van Ramshorst Justus G. V. , Rudolf Carolin , Seserman Diana-Maria , Shao Guodong , Siebicke Lukas , Svoboda Nikolai , Swieter Anita , Carminati Andrea , Freese Dirk , Graf Torsten , Greef Jörg M. , Isselstein Johannes , Jansen Martin , Karlovsky Petr , Knohl Alexander , Lamersdorf Norbert , Priesack Eckart , Wachendorf Christine , Wachendorf Michael , Corre Marife D.
Published: January 2023

Intensively managed open croplands are highly productive but often have deleterious environmental impacts. Temperate agroforestry potentially improves ecosystem functions, although comprehensive analysis is lacking. Here, we measured primary data on 47 indicators of seven ecosystem functions in croplands and 16 indicators of four ecosystem functions in grasslands to assess how alley-cropping agroforestry performs compared to open cropland and grassland. Carbon sequestration, habitat for soil biological activity, and wind erosion resistance improved for cropland agroforestry (P ≤ 0.03) whereas only carbon sequestration improved for grassland agroforestry (P < 0.01). In cropland agroforestry, soil nutrient cycling, soil greenhouse gas abatement, and water regulation did not improve, due to customary high fertilization rates. Alley-cropping agroforestry increased multifunctionality, compared to open croplands. To ameliorate the environmental benefits of agroforestry, more efficient use of nutrients is required. Financial incentives should focus on conversion of open croplands to alley-cropping agroforestry and incorporate fertilizer management.
Gelatin/calcium chloride electrospun nanofibers for rapid hemostasis
Authors: Yu Xinrong , Gao Zichun , Mu Jiaxiang , Lian He , Meng Zhaoxu
Published: January 2023

A novel gelatin/calcium chloride nanofibrous membrane has been prepared as a rapid hemostatic dressing.
A novel donor–acceptor structured diketopyrrolopyrrole-based conjugated polymer synthesized by direct arylation polycondensation (DArP) for highly efficient antimicrobial photothermal therapy
Authors: Wu Zhihui , Wang Jing , Zhao Linlin , Li Chenxi , Lu Yan
Published: January 2023

Novel photothermal conjugated polymers with unique two alternating D–A pairs along backbone was synthesized by direct arylation polycondensation (DArP), achieving highly efficient sterilization.
Synthesis and structure elucidation of triarylmethyl radicals with anthryl substitution
Authors: Wang Peng , Hu Jinlian , Xu Zhuofan , Pu Zhaofangzhou , Sato Sota , Zhang Xiaotao , Hu Wenping , Sun Zhe
Published: January 2023

Two stable triarylmethyl radicals with one or two anthryl substitutions are synthesized in gram scale, and are isolated in the crystalline state.
A fluorescent probe for alkylating agents and its quantification of triflate as a genotoxic impurity
Authors: Zhang Dan , Wang Sifan , Yang Fangxi , Qi Qingrong , Li Yanfang , Huang Wencai
Published: January 2023

A fluorescent probe for the selective and sensitive detection of ethyl triflate, a genotoxic impurity, was developed and its application in fludarabine was demonstrated.
Photocatalytic reductive C–O bond scission promoted by low-work-function Cd single atoms and clusters
Authors: Sun Lulu , Huang Yike , Liu Shiyang , Liu Xiumei , Luo Nengchao , Wang Feng
Published: January 2023

Photocatalytic C–H bond scission over ZnS is promoted by metallic Cd, allowing for the reductive scission of the weakened C–O bond near the C–H bond.
Fluorescence, ultrasonic and photoacoustic imaging for analysis and diagnosis of diseases
Authors: Chu Binbin , Chen Zhiming , Shi Haoliang , Wu Xiaofeng , Wang Houyu , Dong Fenglin , He Yao
Published: January 2023

This feature article focuses on introducing three kinds of non-invasive imaging technology,i.e., fluorescence, ultrasonic and photoacoustic imaging, in which optical and/or acoustic signals are employed for diagnosing various diseases.
Spinel Li4Ti5O12 hollow nanospheres prepared with colloid carbon spheres as templates for high power Li-ion battery anodes
Authors: Chen Yao , Tao Chuanying , Lu Zehua , Zhang Kaicheng , Liu Yong , Xu Gang , Han Gaorong
Published: January 2023

Spinel Li4Ti5O12 hollow nanospheres self-assembled with lamellar nanocrystallites, prepared by employing colloid carbon spheres as templates, exhibit excellent capacity retention.
Effect of antifluorite layer on the magnetic order in Eu-based 1111 compounds, EuTAsF (T = Zn, Mn, and Fe)
Authors: Plokhikh Igor V. , Tsirlin Alexander A. , Khalyavin Dmitry D. , Fischer Henry E. , Shevelkov Andrei V. , Pfitzner Arno
Published: January 2023

Neutron powder diffraction and DFT calculations explain the difference between magnetic structures in layered 1111-type compounds EuTAsF (T = Zn, Mn and Fe) depending on the properties (magnetism, metallicity) of the T-containing layer.
Capillary forces exerted by a water bridge on cellulose nanocrystals: the effect of an external electric field
Authors: Karna Nabin Kumar , Wohlert Jakob , Hjorth Anna , Theliander Hans
Published: January 2023

Capillary forces between cellulose channels depend on the direction and magnitude of an applied electric field. An electric field applied parallel to a solid–liquid interface increases the capillary force while a perpendicular field reduces it.
Synergistic effect of exfoliation and substitutional doping in graphitic carbon nitride for photocatalytic H2O2 production and H2 generation: a comparison and kinetic study
Authors: Mishra Bhagyashree Priyadarshini , Acharya Lopamudra , Parida Kulamani
Published: January 2023

The fabricated exfoliated e-BCN demonstrated stupendous H2O2 production and H2 generation owing to sufficient active surface area and enhanced aromatic π-conjugation, faster charge migration/separation efficiency.
Application of statistical learning and mechanistic modelling towards mapping the substrate electronic space in a Cu-catalyzed Suzuki–Miyaura coupling
Authors: Gómez-Mudarra Francisco A. , Aullón Gabriel , Jover Jesús
Published: January 2023

DFT and statistical learning allow mapping the electronic substrate effects on a Cu-catalyzed Suzuki–Miyaura reaction between iodobenzenes and aryl boronate esters. The resulting substrate map can be used to predict the outcome of similar reactions.
The binding of reducible N2 in the reaction domain of nitrogenase
Authors: Dance Ian
Published: January 2023

Promotional N2 (for the HD reaction of nitrogenase) binding at the exo-Fe2 position of FeMo-co allows reducible N2 (forming NH3) to diffuse in and bind exergonically at the endo coordination position of Fe2 or Fe6 in the central reaction domain.
A remarkably stable acyclic phosphamethine cyanine dye
Authors: Dionisi Erica M. , Binder Justin F. , LaFortune James H. W. , Macdonald Charles L. B.
Published: January 2023

The first long-term air- and moisture-stable phosphamethine cyanine salt is obtained through the use of 4,5-dicyanoimidazolium ligands.
Energy-efficient electrochemical ammonia production from dilute nitrate solution
Authors: Kim Keon-Han , Lee Heebin , Huang Xiaopeng , Choi Jong Hui , Chen Chunping , Kang Jeung Ku , O’Hare Dermot
Published: January 2023

Highly efficient electrochemical nitrate reduction could be key for sustainable ammonia production. Our NiFe LDH/Cu foam electrode exhibits an NH3 selectivity of 95.8% with 98.5% nitrate conversion.
A high-energy aqueous Zn‖NO2 electrochemical cell: a new strategy for NO2 fixation and electric power generation
Authors: Ma Longtao , Chen Shengmei , Yan Wenhao , Zhang Guobin , Ying Yiran , Huang Haitao , Ho Derek , Huang Wei , Zhi Chunyi
Published: January 2023

We developed an aqueous electrochemical Zn‖NO2 cell, which can efficiently capture NO2, then convert it to NO2− and eventually to value-added NH3, while simultaneously producing electric power.
Thermal swing intermittently-operated biological activated carbon filtration for rapid, non-sewered treatment of psychrophilic black water
Authors: Hur Andy Y. , Page Martin A. , Guest Jeremy S.
Published: January 2023

TS-IOBAC filtration is an energy-efficient biological treatment process for decentralized wastewater treatment in cold climates.
Decarboxylative arylation with diaryliodonium(iii) salts: alternative approach for catalyst-free difluoroenolate coupling to aryldifluoromethyl ketones
Authors: Kikushima Kotaro , Yamada Kohei , Umekawa Narumi , Yoshio Natsumi , Kita Yasuyuki , Dohi Toshifumi
Published: January 2023

α-Aryl-α,α-difluoroketones were synthesizedviadecarboxylative arylation using diaryliodonium salts under catalyst-free conditions without organometallic intermediates. The products can be transformed into various difluorinated functional groups.
Enhanced electrical properties of microcellular polymer nanocomposites via nanocarbon geometrical alteration: a comparison of graphene nanoribbons and their parent multiwalled carbon nanotubes
Authors: Salari Meysam , Habibpour Saeed , Hamidinejad Mahdi , Mohseni Taromsari Sara , Naguib Hani E. , Yu Aiping , Park Chul B.
Published: January 2023

Geometric factors of nanofillers considerably govern the properties of conductive polymer composites (CPCs).
Distance measurements between 5 nanometer diamonds – single particle magnetic resonance or optical super-resolution imaging?
Authors: Pinotsi Dorothea , Tian Rui , Anand Pratyush , Miyanishi Koichiro , Boss Jens M. , Chang Kevin Kai , Welter Pol , So Frederick T.-K. , Terada Daiki , Igarashi Ryuji , Shirakawa Masahiro , Degen Christian L. , Segawa Takuya F.
Published: January 2023

5 nanometer sized detonation nanodiamonds (DNDs) are studied as potential single-particle labels for distance measurements in biomolecules.
Hemicurcuminoids (1-styryl-1,3-diketones) – valuable multi-faceted building blocks for organic synthesis
Authors: Zimnitskiy Nikolay S. , Korotaev Vladislav Yu. , Barkov Alexey Yu. , Kochnev Ivan A. , Sosnovskikh Vyacheslav Ya.
Published: January 2023

For the first time, a review has been conducted on the methods for the synthesis, as well as on the chemical, physical and biological properties, of 5-arylpent-4-ene-1,3-diones (hemicurcuminoids).
Metal-metalloid bond containing complexes of the bulky organotellurium ligand: applications in catalysis of C–O coupling and aldehyde to amide transformation reactions
Authors: Oswal Preeti , Arora Aayushi , Purohit Suraj , Bahuguna Anurag , Sharma Pankaj , Roy Jiben , Kumar Arun
Published: January 2023

Air and moisture insensitive palladium and ruthenium complexes of the organotellurium ligand and their application in C–O coupling and aldehyde to amide transformation.
Synthesis of disulfide surrogate peptides incorporating an ethylene glycol bridge
Authors: Wei Xiao-Xiong , Cui Ji-Bin , Zhao Rui , Luo Jie , Li Yi-Ming , Bierer Donald , Shi Jing
Published: January 2023

We report a new diaminodiacid containing an ethylene glycol bridge for the synthesis of disulfide surrogate peptides.
Organic redox cascade cyclization of 2-alkynylquinones by ascorbic acid in combination with a copper catalyst and its application to formal synthesis of liphagal
Authors: Jeong Taejoo , Okanishi Yusuke , Yotsui Sora , Kim In Su , Yoshimitsu Takehiko
Published: January 2023

The combination of a quinone-ascorbic acid organic redox reaction and a concomitant copper catalysis in situ enables new approach to hydroxybenzofurans with structural variations.
pH-Responsive lower critical solution temperature behaviour of a dibenzo-24-crown-8 based low-molecular-weight gelator in water
Authors: Zheng Bo , Zhang Huizheng , Wang Na , Gao Lingyan
Published: January 2023

A dibenzo-24-crown-8 based low-molecular-weight gelator can form a gel in aqueous media and show lower critical solution temperature behaviour, which can be switched off and on by adding base and acid.
Multiple switchable circularly polarized luminescence from nucleotide/terbium(iii) complexes
Authors: Yang Chujing , Zhang Zhiwei , Chen Jingqi , Zhang Xinying , Dai Yankai , Li Xuyi , Chen Yingying , Xu Jiaqiang , Feng Lingyan
Published: January 2023

Nucleotide and terbium complexes exhibit circularly polarized luminescence and can be reversed by a magnetic field, pH, and nucleotides.
Assemblies of poly(N-vinyl-2-pyrrolidone)-based double hydrophilic block copolymers triggered by lanthanide ions: characterization and evaluation of their properties as MRI contrast agents
Authors: Yon Marjorie , Gibot Laure , Gineste Stéphane , Laborie Pascale , Bijani Christian , Mingotaud Christophe , Coutelier Olivier , Desmoulin Franck , Pestourie Carine , Destarac Mathias , Ciuculescu-Pradines Diana , Marty Jean-Daniel
Published: January 2023

MRI probes based on HPICs are described.
Wearable chemical sensors based on 2D materials for healthcare applications
Authors: Zhang Ruifang , Jiang Jing , Wu Wenzhuo
Published: January 2023

We provided an overview of recent advances in 2D-material-based wearable chemical sensors for healthcare applications. We also explored the challenges and opportunities associated with designing and implementing 2D wearable chemical sensors.
Preclinical safety assessment of red emissive gold nanocluster conjugated crumpled MXene nanosheets: a dynamic duo for image-guided photothermal therapy
Authors: Singh Barkha , Bahadur Rohan , Maske Priyanka , Gandhi Mayuri , Singh Dipty , Srivastava Rohit
Published: January 2023

We show the synthesis method of red emissive gold nanocluster conjugated crumpled MXene nanosheets. This material was applied as bio-imaging and PTT agent. Thein vivotoxicity was performed in ratsviaboth the oral and I.V. modes of administration.
A sprayed graphene transistor platform for rapid and low-cost chemical sensing
Authors: Fenech-Salerno Benji , Holicky Martin , Yao Chengning , Cass Anthony E. G. , Torrisi Felice
Published: January 2023

Lab-on-printed circuit board platform for scalable electrochemically-gated graphene field effect transistors test strips, measuring pH and Na+ ion concentration.
Magnetic nanocomposites for magneto-promoted osteogenesis: from simulation auxiliary design to experimental validation
Authors: Hao Lili , Li Jiaxiang , Wang Peng , Wang Zongliang , Wang Yu , Zhu Yongzhan , Guo Min , Zhang Peibiao
Published: January 2023

Computer simulation auxiliary design of magnetic nanocomposites for magneto-promoted osteogenesis through activation of the mechanically sensitive ion channel Piezo1.
Single particle level dynamics of photoactivation and suppression of Auger recombination in aqueous Cu-doped CdS quantum dots
Authors: Das Sharmistha , Rana Gourab , Ali Fariyad , Datta Anindya
Published: January 2023

Fluence dependent fluorescence correlation spectroscopy for elucidation of Cu-doping-induced suppression of Auger recombination in aqueous CdS quantum dots.
Metal-free direct C-6–H alkylation of purines and purine nucleosides enabled by oxidative homolysis of 4-alkyl-1,4-dihydropyridines at room temperature
Authors: Jiang Qingsong , Liu Xiguang , Wang Weili , Chen Yiwen , Yu Mingwu
Published: January 2023

The highly C6-regioselective alkylation of purines and purine nucleosidesviaoxidative homolysis of 4-alkyl-1,4-dihydropyridines at room temperature without metal catalysts and additional acids is reported for the first time.
Synthesis of functionalized 3-aryl-3H-benzofuranone derivatives from aryl acetate via [3 + 2] annulation of 1,4-dihydroxy-2-naphthoic acid ester
Authors: Wang Huan , Zhou Yuxiang , Xie Ying , Liu Yi , Li Yulong , Zhang Hao , Long Jilang
Published: January 2023

A new and efficient [3 + 2] cascade reaction has been developed for the synthesis of 3-aryl-3H-benzofuranone derivatives from aryl acetate via [3 + 2] annulation of 1,4-dihydroxy-2-naphthoic acid ester or 1,4-naphthoquinone.
A tridentate phenoxy-phosphine (POP) divalent chromium complex and its reactivities in olefin polymerization
Authors: Ji Li , Song Ping , Zhou Youyun , Sun Xiu-Li , Gao Yanshan , Tang Yong
Published: January 2023

We reported the synthesis and characterization of a Cr(ii) complex based on a tridentate phenoxy-phosphine ligand and studied its reactivities in ethylene and norbornene homopolymerization and ethylene copolymerization with norbornene or 1-octene.
Bis(pentafluorophenyl)borane-catalyzed E-selective isomerization of terminal alkenes to internal alkenes
Authors: Phatake Ravindra S. , Müller Tizian , Averdunk Arthur , Gellrich Urs
Published: January 2023

The bis(pentafluorophenyl)borane-catalyzed E-selective isomerization of terminal alkenes to internal alkenes via a hydroboration/retro-hydroboration sequence is reported.
Liposomes loaded with dual clinical photosensitizers for enhanced photodynamic therapy of cervical cancer
Authors: Alimu Gulinigaer , Yan Ting , Zhu Lijun , Du Zhong , Ma Rong , Fan Huimin , Chen Shuang , Alifu Nuernisha , Zhang Xueliang
Published: January 2023

A novel type of PS (Ce6-MB@Lips) which could be excited by a NIR laser was synthesized. After effective cell internalization, the stable Ce6-MB@Lips showed high phototoxicity and ROS production capacity, and excellent ability to promote tumor cell apoptosis in vitro.
Metal peroxides as potential photocatalysts for environmental remediation
Authors: Prasanna V. Lakshmi , Harikaran Dhakshnamoorthi , Avisar Dror , R. Vijayaraghavan.
Published: January 2023

Metal peroxides as a chemical source of H2O2 and semiconductor photocatalysts.
Microstructure, grain and nanowire growth during selective laser melting of Ag–Cu/diamond composites
Authors: Xin Chenxing , Zhao Xiya , Geng Haoze , Hao Liang , Li Yan , Chen Tao , Gong Ping
Published: January 2023

Selective laser melting technique is a viable alternative to fabricating metal matrix composites with controllable structures; however, its implementation remains challenging because of the unpredicted defects arising from the reinforcement.
Virtual screening and activity evaluation of human uric acid transporter 1 (hURAT1) inhibitors
Authors: Yang Yacong , Hu Yu , Yao Fengli , Yang Jinbo , Ge Leilei , Wang Peng , Xu Ximing
Published: January 2023

Alphafold2 was used to predict URAT1 protein structure, then the docking sites were identified, and three hit compounds were obtained through virtual screening and bioactivity verification.
Synthesis of polynorbornadienes by ring-opening metathesis polymerization and their saturated derivatives bearing various ester groups and carboxyl groups
Authors: Lin Xiaoxue , Shi Jianjun , Niwayama Satomi
Published: January 2023

Polymer libraries were synthesized in a controlled living manner from half-esters efficiently prepared by the selective monohydrolysis of symmetric diesters.
Development of a continuous synthesis process for carbamazepine using validated in-line Raman spectroscopy and kinetic modelling for disturbance simulation
Authors: Glace Matthew , Wu Wei , Kraus Harrison , Acevedo David , Roper Thomas D. , Mohammad Adil
Published: January 2023

Mitigation of failure modes in the continuous synthesis (CS) of a drug substance (DS) has the potential to widen the adoption of continuous manufacturing (CM) technologies by the pharmaceutical industry.
Mapping hyperbolic order in curved materials
Authors: Pedersen Martin Cramer , Hyde Stephen T. , Ramsden Stuart , Kirkensgaard Jacob J. K.
Published: January 2023

We present a new method for visualisation and analysis of patterns on triply periodic negatively curved surfaces by mapping to two-dimensional hyperbolic space.
Membrane-mediated dimerization of spherocylindrical nanoparticles
Authors: Sharma Abash , Zhu Yu , Spangler Eric J. , Carrillo Jan-Michael Y. , Laradji Mohamed
Published: January 2023

Dimerization of two spherocylindrical nanoparticles (SCNPs) into a wedged dimer. Dimeric endocytosis requires that the SCNPs adhere simultaneously at nearby locations.
The adsorption kinetics and mechanism of odorous gases onto textile fibers
Authors: Bai Wenli , Yu Hao , Liu Longlong , Pakdel Esfandiar , Tang Bin , Su Hongli , Hurren Christopher , Liu Lei , Wang Jinfeng , Wang Xungai
Published: January 2023

A new insight into odor adsorption onto common fibers promotes health and wellbeing through managing malodor and indoor air pollutants.
Superior thermoelectric properties of bulk and monolayer fullerene networks
Authors: Li Wenwen , Yang Rui , Sun Mengtao
Published: January 2023

The structure, electronic energy band, and thermoelectric properties of bulk and monolayer fullerene (C60) networks were analyzed in detail, stimulated by the successful experimental synthesis of C60 networks [Hou L., et al., Synthesis of a monolayer fullerene network, Nature, 2022, 606, 507].
Manipulating the interaction of Pt NPs with N-hollow carbon spheres by F-doping for boosting oxygen reduction/methanol oxidation reactions
Authors: Lyu Chaojie , Cheng Jiarun , Yang Yuquan , Wu Jiwen , Wu Kaili , Yang Yunguo , Lau Woon-Ming , Wang Ning , Pang Dawei , Zheng Jinlong
Published: January 2023

F-doping enhances the strong interaction between Pt NPs and carbon skeleton, and leads to higher Ptx+content that can effectively adsorb *OOH intermediates for direct 4e−pathway in ORR, also promote the complete oxidation of COadsto CO2in MOR.
Perovskite-quantum dot hybrid solar cells: a multi-win strategy for high performance and stability
Authors: Huang Ke , Liu Junlong , Yuan Jianjuan , Zhao Wenchao , Zhao Kui , Zhou Zhihua
Published: January 2023

A comprehensive and critical review of the recent progress on hybrid QD-perovskite solar cells was presented with the aim of advancing their commercial applications.
A tetrathiafulvalene salt of the nitrite (NO2−) anion: investigations of the spin-Peierls phase
Authors: Soriano Loïc , Orio Maylis , Pilone Olivier , Jeannin Olivier , Reinheimer Eric , Quéméré Nicolas , Auban-Senzier Pascale , Fourmigué Marc , Bertaina Sylvain
Published: January 2023

The first nitrite salt of a tetrathiafulvalene derivative exhibits a rare chessboard-like organization of the conducting stacks, with a spin-Peierls transition at 70 K.
Visible/solar-light-driven thiyl-radical-triggered synthesis of multi-substituted pyridines
Authors: Sahoo Ashish Kumar , Rakshit Amitava , Pan Avishek , Dhara Hirendra Nath , Patel Bhisma K.
Published: January 2023

A light-mediated synthesis of thio-functionalized pyridines has been achieved using γ-ketodinitriles and thiophenols under green LED irradiation or direct sunlight.
Numerical‐discrete‐scheme‐incorporated recurrent neural network for tasks in natural language processing
Authors: Liu Mei , Luo Wendi , Cai Zangtai , Du Xiujuan , Zhang Jiliang , Li Shuai
Published: January 2023

A variety of neural networks have been presented to deal with issues in deep learning in the last decades. Despite the prominent success achieved by the neural network, it still lacks theoretical guidance to design an efficient neural network model, and verifying the performance of a model needs excessive resources. Previous research studies have demonstrated that many existing models can be regarded as different numerical discretizations of differential equations. This connection sheds light on designing an effective recurrent neural network (RNN) by resorting to numerical analysis. Simple RNN is regarded as a discretisation of the forward Euler scheme. Considering the limited solution accuracy of the forward Euler methods, a Taylor‐type discrete scheme is presented with lower truncation error and a Taylor‐type RNN (T‐RNN) is designed with its guidance. Extensive experiments are conducted to evaluate its performance on statistical language models and emotion analysis tasks. The noticeable gains obtained by T‐RNN present its superiority and the feasibility of designing the neural network model using numerical methods.
Performance improvement of an indirect AC/DC/AC matrix converter‐based IPMSM drive system under unbalanced three‐phase input voltages
Authors: Liu Tian‐Hua , Li Hong‐Wen
Published: January 2023

Most matrix converters use indirect control, which includes a three‐phase virtual AC/DC converter and a virtual inverter, to control their nine AC switches. However, matrix converters do not use electrolytic capacitors to store energy. As a result, unbalanced three‐input voltages directly cause unbalanced three‐phase output voltages, which deteriorate the performance of IPMSM drive systems. To solve this problem, this paper proposes an improved method, which includes inverter stage control and AC/DC stage control, for matrix converter‐based IPMSM drive systems under unbalanced three‐phase input voltages. The inverter stage control adjusts the duty cycles of the virtual inverter to compensate for the fluctuations of the virtual DC‐bus voltage. Therefore, the harmonic currents of the IPMSM are significantly reduced, and the speed ripples of the IPMSM are reduced as well. The AC/DC stage control uses a virtual AC/DC converter to control the three‐phase input currents near sinusoidal waveforms with a unity power factor. Finally, a hybrid algorithm that combines the inverter stage control and the AC/DC stage control is demonstrated. A digital signal processor, type SH 7237, and a field programmable gate array, type 10M16SAU16917G, are used in parallel as the computational and control center.
Hybridization of particle swarm optimization algorithm with neural network for COVID‐19 using computerized tomography scan and clinical parameters
Authors: Sameer Humam Adnan , Gharghan Sadik Kamel , Mutlag Ammar Hussein
Published: January 2023

The 2019 coronavirus disease began in Wuhan, China, and spread worldwide. This pandemic was concerning, given its significant and worrying impact on human health. Strategies to manage the disease begin with diagnosing the infection, often using the real‐time reverse transcription polymerase chain reaction (RT‐PCR) assay. However, this process is time intensive. Therefore, alternative rapid methods to diagnose the coronavirus with high accuracy are needed. X‐ray and computerized tomography (CT) scans are reasonable solutions for rapid coronavirus diagnosis. The dataset of 500 patients was tested, including 286 uninfected patients and 214 infected with COVID‐19. Clinical parameters, including heart rate (HR), temperature (T), blood oxygen level, D‐dimer, and CT scan, including red‐green‐blue (RGB) pixel values of the left and right lungs, were collected from 500 patients and used to train an artificial neural network (ANN) to diagnose coronavirus. The ANN was hybridized with a particle swarm optimization (PSO) algorithm to improve diagnosis accuracy. The results show that the proposed PSO‐ANN method significantly improved diagnosis accuracy (98.93%), sensitivity (100%), and specificity (98.13%). The effectiveness of the proposed method was confirmed by comparing the findings with those of previous studies.
Fast frequency response technology of photovoltaic power plant based on equivalent modelling
Authors: Yin Yu
Published: January 2023

With the centralized access of large capacity and high proportion of new energy to the power grid, the power structure has undergone great changes, and the fast frequency response resources available to the power grid have gradually decreased. If high‐power DC blocking occurs, it will pose a serious threat to the frequency security of the power grid, and the frequency regulation pressure of the power grid and the risk of safe operation will continue to increase. To this end, a fast frequency response technology for photovoltaic power plants based on equivalent modelling is proposed. According to the principle of equivalent modelling, the equivalent model of a single unit of photovoltaic power station is established through the parameters of photovoltaic array, photovoltaic inverter, unit transformer, unit transformer and collector line. According to the fast frequency response performance requirements of photovoltaic power plants, combined with the characteristics of photovoltaic power plants, a feasible scheme for fast frequency response of photovoltaic power plants is introduced. The case study on the implementation of fast frequency response project in photovoltaic power station shows that according to the order and type of AGC command and fast frequency response command, photovoltaic power station has conducted command superposition tests under 50 ±0.2 Hz and 50 ±0.09 Hz disturbance amplitudes respectively, and the results are qualified. The integration of automatic generation control/automatic voltage control (AGC/AVC) and fast frequency response function of photovoltaic power station is realized by using relevant technologies, so that the photovoltaic power station can actively support the grid frequency and voltage.
Hubble Space Telescope survey of Magellanic Cloud star clusters
Authors: Milone A. P. , Cordoni G. , Marino A. F. , D’Antona F. , Bellini A. , Di Criscienzo M. , Dondoglio E. , Lagioia E. P. , Langer N. , Legnardi M. V. , Libralato M. , Baumgardt H. , Bettinelli M. , Cavecchi Y. , de Grijs R. , Deng L. , Hastings B. , Li C. , Mohandasan A. , Renzini A. , Vesperini E. , Wang C. , Ziliotto T. , Carlos M. , Costa G. , Dell’Agli F. , Di Stefano S. , Jang S. , Martorano M. , Simioni M. , Tailo M. , Ventura P.
Published: January 2023

In the past few years, we have undertaken an extensive investigation of star clusters and their stellar populations in the Large and Small Magellanic Clouds (LMC and SMC) based on archival images collected with the Hubble Space Telescope. We present photometry and astrometry of stars in 101 fields observed with the Wide Field Channel of the Advanced Camera for Surveys and the Ultraviolet and Visual Channel and the Near-Infrared Channel of Wide Field Camera 3. These fields comprise 113 star clusters. We provide differential-reddening maps for those clusters with significant reddening variations across the field of view. We illustrate various scientific outcomes that arise from the early inspection of the photometric catalogs. In particular, we provide new insights into the extended main-sequence turnoff (eMSTO) phenomenon: (i) We detected eMSTOs in two clusters, KMHK 361 and NGC 265, which had no previous evidence of multiple populations. This finding corroborates the conclusion that the eMSTO is a widespread phenomenon among clusters younger than ∼2 Gyr. (ii) The homogeneous color-magnitude diagrams (CMDs) of 19 LMC clusters reveal that the distribution of stars along the eMSTO depends on cluster age. (iii) We discovered a new feature along the eMSTO of NGC 1783, which consists of a distinct group of stars on the red side of the eMSTO in CMDs composed of UV filters. Furthermore, we derived the proper motions of stars in the fields of view of clusters with multi-epoch images. Proper motions allowed us to separate the bulk of bright field stars from cluster members and investigate the internal kinematics of stellar populations in various LMC and SMC fields. As an example, we analyze the field around NGC 346 to disentangle the motions of its stellar populations, including NGC 364 and BS 90, young and pre-main-sequence stars in the star-forming region associated with NGC 346, and young and old field stellar populations of the SMC. Based on these results and the fields around five additional clusters, we find that young SMC stars exhibit elongated proper-motion distributions that point toward the LMC, thus providing new evidence for a kinematic connection between the LMC and SMC.
Les enjeux éthiques du suivi à long terme des cancers pédiatriques
Authors: Camus Agathe , Henry Julie
Published: January 2023

Dans l’article précédent, nous avons abordé les contours fragiles et fluctuants de ce qui est appréhendé comme une « vie normale » par les personnes guéries d’un cancer dans l’enfance ainsi que la manière dont celle-ci devient un objet d’interlocution complexe et singulier pour les professionnels de santé impliqués dans le suivi à long terme des cancers pédiatriques. Le présent article décrit la seconde étape de l’enquête qualitative que nous avons menée, reposant sur la mise en place d’un groupe de réflexion éthique. Elle a permis de révéler la manière dont le suivi à long terme vient questionner et transformer les pratiques de soin et de suivi dans le champ de la cancérologie pédiatrique. Il précise également l’apport spécifique de la philosophie de terrain dans ce contexte.
Maltraitance envers les enfants et Covid-19
Authors: Loiseau Mélanie , Cottenet Jonathan , Gilard-Pioc Séverine , François-Purssell Irène , Mikaeloff Yann , Quantin Catherine
Published: January 2023

En France, au début de l’année 2020, environ 690 000 vies ont pu être épargnées grâce au confinement général de la population et aux mesures restrictives de lutte contre la Covid-19. Conséquence inattendue, ces mesures ont eu un impact sur une autre frange vulnérable de la population : celle des jeunes enfants, pour lesquels il a été démontré une augmentation des maltraitances subies à cette période. À partir de données de la littérature et de l’apport de nos travaux de recherche dans le domaine, nous proposons une documentation de cette crise des violences intra-familiales, intriquée dans la crise sanitaire de la Covid-19.
Topological structures for microchannel heat sink applications – a review
Authors: Lu Kaijie , Wang Chunju , Wang Changrui , Fan Xueliang , Qi Fei , He Haidong
Published: January 2023

The microchannel heat sink (MCHS) has the advantages of small heat transfer resistance, high heat transfer efficiency and small size, which exhibits good heat transfer performance in the field of active heat dissipation of electronic devices integrated with high heat flux density. In this paper, the application of MCHS in thermal management is reviewed in recent years, and the research progress of microchannel topology on enhancing heat transfer performance is summarized. Firstly, the research progress on the cross-sectional shape of the microchannel shows that the heat transfer area and fluid flow dead zone of the microchannel is the keys to affecting the heat transfer performance; Secondly, the microchannel distribution and the bionic microchannel structure have a great role in enhancing heat transfer performance, especially in microchannel temperature uniformity; Thirdly, the disturbing effect caused by interrupted structures in microchannels such as ribs and concave cavities has become a hot topic of research because it can weaken the thermal boundary layer and increase heat dissipation. Finally, the commonly used MCHS materials and cooling media are summarized and introduced. Based on the above reviews of MCHS research and applications, the future trends of MCHS topologies are presented.
« Les réacteurs français ont un meilleur niveau de sûreté que lors de leur mise en service »
Authors: Dupin Ludovic
Published: January 2023

Alors que les premiers réacteurs nucléaires atteignent les 40 ans d’activité, la question de leur fonctionnement à long terme est de plus en plus importante. C’est l’Autorité de sûreté nucléaire (ASN) qui sera seule décisionnaire sur ce sujet. Son président Bernard Doroszczuk nous éclaire sur les grands enjeux de cette réflexion.
La sûreté à l’épreuve de la complexité : les limites de l’action managériale
Authors: Krasnopevtseva Natalia Jubault , Thomas Catherine , Kaminska Renata
Published: January 2023

Les « systèmes presque totalement sûrs » se veulent reposer sur une sûreté réglée visant à prévoir tout ce qui est possible, et une sûreté gérée prévue pour faire face à l’imprévu. Mais l’accumulation des règles ou leur mauvaise application peut fragiliser l’édifice. Identifier les limites de l’action managériale est nécessaire pour accroître la fiabilité de ces systèmes et en gérer la sophistication.
Vie des populations et radioprotection dans les territoires contaminés
Authors: Schneider Thierry
Published: January 2023

Comment vivent les populations confrontées aux questions de radioprotection en situation post-accidentelle ? Comment vivre dans ces territoires contaminés ? Les cas de Tchernobyl depuis le début des années 1990 et de Fukushima apportent des réponses, notamment dans le cadre des activités de la Commission internationale de protection radiologique (CIPR).
Les effets biologiques des rayonnements ionisants
Authors: Prévôt-Bitot Nathalie
Published: January 2023

L’étude de l’impact des rayonnements ionisants sur l’ADN, les organes et l’organisme est un sujet de recherche vivant et très actif. La compréhension des mécanismes biologiques et des effets-seuil est au coeur des stratégies de radioprotection.
Effects of Exercise Intervention Based on Self-efficacy Theory on
Pregnant Women with Gestational Diabetes Mellitus
Authors: Tan Yingyao , Huang Fangying , Wang Yan , Lan Yutao , Cai Shu
Published: January 2023

Background During pregnancy, gestational diabetes mellitus (GDM)is a
common complication. Although some exercise programs have been recommended
clinically, many pregnant women have low exercise compliance, making it
difficult to effectively control blood sugar. Therefore, this study constructed
an exercise intervention plan based on self-efficacy theory and explored the
effect of the program on blood glucose and pregnancy outcomes in patients with
gestational diabetes mellitus.

Methods A randomized controlled trial was conducted. A usual exercise
program was implemented for the participants in the control group, and the
participants in the intervention group received an exercise program on the basis
of the control group and combined with the self-efficacy theory. Participants
were assessed based on exercise self-efficacy, blood glucose, weight gain,
exercise compliance, and pregnancy outcomes at week 4, week 8 and week 12.

Results One hundred three gestational diabetes mellitus patients were
recruited at baseline, 53 in the intervention group and 50 in the control group.
After the intervention, the exercise self-efficacy score and exercise compliance
of the intervention group were higher than those of the control group
(P<0.05). Fasting blood glucose, 2-h post-prandial plasma glucose,
weight gain during the intervention period, incidence of neonatal hypoglycemia,
and incidence of gestational hypertension were lower than those in the control
group (P<0.05).

Conclusion Implementing an exercise intervention based on self-efficacy
theory for gestational diabetes mellitus patients can improve exercise
self-efficacy and exercise compliance, effectively control blood glucose and
weight gain, improve pregnancy outcomes, and promote maternal and infant
safety.