bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of the patency of the left portal vein during mesoportal shunting in children with extrahepatic portal hypertension
Authors: Sokolova Daria A. , Mitupov Zoricto B. , Kurtak Nikita D. , Razumovsky Alexander Y.
Published: July 2021

BACKGROUND: One of the most common causes of extrahepatic portal hypertension in children is portal vein thrombosis. The causes of this disease are different and, in most cases, remain unrecognized. Along with this, the mesoportal shunt (Rex shunt) proved itself and today is considered the gold standard to treat extrahepatic portal hypertension in children. The restoration of hepatopetal blood flow eliminates gastroesophageal bleeding, splenomegaly, hypersplenism, and many other complications. For the results of mesoportal shunt to be successful, several conditions must be met, one of which is the patency of the umbilical portion of the left portal vein. Despite the importance of preoperative diagnostics of the patency of this area, the most optimal instrumental research method has not yet been found.
AIM: This literature review aims to highlight the main issues of extrahepatic portal hypertension etiopathogenesis, surgical treatment methods, and the most effective preoperative diagnostic methods to assess the patency of the left portal vein.
RESULTS: The authors analyzed the sources of domestic and foreign literature on the etiology, pathogenesis of HSV in children, and laboratory and instrumental diagnostic methods to assess the patency of the PVI to plan the mesoportal shunting operation.
CONCLUSIONS: Extrahepatic portal hypertension is a polyetiological disease with a possible hereditary predisposition to a thrombotic process under the influence of various triggers. The most common causes of portal vein thrombosis are omphalitis and umbilical vein catheterization in the neonatal period. Unfortunately, to date, none of the existing instrumental diagnostic methods can reliably answer the question about left portal vein patency. Due to the small number of works, the lack of a unified view on the problem of preoperative diagnosis of patients with extrahepatic portal hypertension, we could not reliably determine the specificity, sensitivity, and accuracy of each instrumental method. Therefore, we could not identify the gold standard method. Nevertheless, with further improvement of the methods for preoperative assessment of the left portal vein patency, surgeons will be more likely to predict the successful outcome of mesoportal shunting, which will generally affect the surgical treatment quality of extrahepatic portal hypertension in children.
Extracorporeal detoxification for septic complications in children during the acute period of severe combined craniocerebral trauma
Authors: Novikova Tatyana A. , Yeletskaya Elena V. , Ivanova Tatyana F. , Amchislavsky Valery G.
Published: July 2021

BACKGROUND: The clinical application of extracorporeal detoxification methods in patients with severe concomitant traumatic brain injury has several features and limitations due to intracranial hypertension, traumatic cerebral edema, and the risk of their growth during extracorporeal detoxification. The modern literature presents the results of using extracorporeal detoxification methods in severe concomitant trauma in children. However, practically no data are available on the possibility of their use in severe concomitant craniocerebral trauma, which determines the relevance of research in this direction.
AIM: This study aims to improve the treatment results of affected children with severe concomitant craniocerebral trauma with the addition of septic complications using extracorporeal detoxification methods.
MATERIALS AND METHODS: The experience using extracorporeal detoxification methods, including prolonged veno-venous hemodiafiltration combined with LPS sorption and plasma separation membrane in patient intensive care with severe concomitant craniocerebral trauma complicated by sepsis and septic shock development, is presented.
RESULTS: The use of extracorporeal detoxification methods contributed to eliminating septic shock, stabilization of hemodynamic and internal homeostasis parameters, and regression of multiple organ failure in patients with severe concomitant traumatic brain injury. Monitoring the intracranial pressure and preventing disequilibrium syndrome development enabled avoiding an increase in intracranial hypertension in studied patients.
CONCLUSIONS: Timely and adequate use of extracorporeal detoxification methods improves the clinical course of the acute period of traumatic illness in children with severe concomitant traumatic brain injury. The safe use of efferent therapy methods in patients with severe concomitant traumatic brain injury is ensured by invasive monitoring of intracranial pressure and preventing the development of disequilibrium syndrome.
Direct inguinal hernias in children
Authors: Svarich Vyacheslav G. , Kagantsov Ilya M. , Svarich Violetta A.
Published: July 2021

AIM: Based on the accumulated clinical material, this study aims to show the possibilities of diagnosing and treating direct inguinal hernias in children.
MATERIALS AND METHODS: During the period from 2000 to 2020, 3221 children with inguinal hernias were treated in the surgical department of the Republican Childrens Clinical Hospital in Syktyvkar. Of the above group of children with inguinal hernias, seven patients (0.22%) had direct inguinal hernias. The above was confirmed by ultrasound examination. In laparoscopic imaging, a rectal hernia was defined as a recess of the peritoneum of a stellate or rounded shape in the projection of the medial umbilical fossa. Two patients underwent the Bassini herniation procedure. Two children underwent laparoscopic hernia repair with intracorporeal suture insertion. In three patients, hernia repair was performed using the PRMS method.
RESULTS: Long-term results were followed up from six months to 15 years. Immediate and postoperative complications were noted. No recurrence of hernia was reported.
CONCLUSIONS: When establishing direct inguinal hernia diagnosis in children is clinically determined in the form of a rounded, soft-elastic formation localized medially and above the Pupart ligament next to the projection of the external (superficial) inguinal ring of the inguinal canal. It is easily set into the abdominal cavity with rumbling and confirmed by ultrasound examination results. The most preferred treatment method for direct inguinal hernia in children, in our opinion, is hernia repair using the percutaneous internal ring suturing (PIRS) method.
Strategy for the prevention of bacterial complications with inhaled nitrogen oxide in newborns
Authors: Pukhtinskaya Marina G. , Estrin Vladimir V.
Published: July 2021

BACKGROUND: The nitrogen oxide molecule (NO) is a one of the most important factors in the anti-infectious resistance of the bodys immune system.
AIM: This study aims to improve the effectiveness of preventing bacterial complications by including nitric oxide inhalations as part of traditional intensive care.
MATERIALS AND METHODS: Ninety-seven full-term newborns without signs of bacterial complications were included in a controlled, randomized, blind clinical trial. The main group (n = 44) received inhaled nitrogen oxide (iNO). The control group (n = 53) did not receive iNO. On days 1, 5, and 20 the plasma concentrations of IL-1, IL-6, IL-8, TNF-, G-CSF, sFas, FGF, and NO were determined by capture ELISA; CD3+CD19, CD3CD19+, CD3+CD4+, CD3+CD8+, CD69+, CD71+, CD95+, CD3+HLA-DR+, CD14+, CD3CD56+, Annexin-V+/FITC; PI+/PE immunophenotype analysis.
RESULTS: In the main group, sepsis developed in 4 patients and 13 controls (p1 = 0.04; p2 = 0.005). Fatalities occurred in 6 patients, and 10 controls (p1 = 0.37; p2 = 0.59) in the main group. The median duration of the IVL in the main group was 5 days, and 10 days for controls (p = 0.00007). Stays in ORIT were main 11 days for patients in the main group, and 15 days for controls (p = 0.026). On day 3, when compared with controls, patients in the main group had significantly reduced (p 0.05) of TNF-, IL-8 and IL-6, CD3+CD69+, CD3+CD95+, lymphocytes in apoptosis, increasing (p 0.05) G-CSF, sFas, FGF, NO; CD14+, CD3 +CD19.
CONCLUSIONS: iNO used as a part of intensive care decreases the frequency of sepsis development, the duration of mechanical ventilation, and hospitalization. iNO also tends to decrease the lethal outcome frequency, reduces cytokine aggression, inhibits lymphocyte apoptosis, activates the monocyte-macrophage immunity and proliferative processes. It is appropriate to continue research.
Congratulations to colleagues
Authors: Gorbachev Oleg S.
Published: July 2021

Congratulations pediatric surgeons, celebrating their anniversaries.
The 50-th anniversary of Dmitry A. Morozov
Authors: Rozinov Vladimir M.
Published: July 2021

Description of the professional activities and merits of the pediatric surgeon celebrating his anniversary.
The days of pediatric surgery in Vyatsk Land
Authors: Razin Maksim P. , Shumikhin Vasil S.
Published: July 2021

A brief report of the Russian Symposium of Pediatric Surgeons and the 60th Conference of Student Scientific Circles of Pediatric Surgeons held in April 2021. The topic of the symposium Complications of acute appendicitis in children aroused great interest among the delegates, 96% of whom were ill and vaccinated against COVID-19, and an extensive online audience. Based on the results of this symposium, the decision was made to transform its content into clinical guidelines. The winners of the student research papers were determined.
Wastewater Disposal Has Not Significantly Altered the Regional Stress State in Southern Kansas
Authors: Skoumal Robert J. , Cochran Elizabeth S.
Published: July 2021

Wastewater disposal is primarily responsible for the increased seismicity rate since ∼2013 in southern Kansas. Previous work that used shear-wave splitting (SWS) in southern Kansas interpreted an ∼90° temporal rotation in the fast polarization direction and attributed it to increased pore pressures resulting from fluid injection. However, this interpreted rotation coincided with a change in the stations used to make the SWS measurements. We investigate the temporal variability of fast azimuths in southern Kansas by making SWS measurements on earthquake families with similar source–receiver paths recorded on a stable local seismic network. We select high-quality SWS measurements by investigating the stability of results across 65 different frequency bands between 0.5 and 15 Hz. We find that the fast polarization direction in southern Kansas is relatively constant with an average east-northeast (∼N79°E) orientation between 2014 and 2017. Our fast polarization measurements are primarily a reflection of the maximum principal horizontal stress direction (SHmax). We observe a slight spatial change in SHmax to the northeast (∼N55°E) near the Nemaha ridge in Oklahoma. However, we do not observe any significant temporal rotation of SHmax or variation in delay time (i.e., crack density) in southern Kansas, contrary to the earlier study. The previously interpreted ∼90° rotation may either be a reflection of a very local stress change or a misinterpretation of SWS results potentially due to the use of inconsistent source–receiver paths. Our SWS measurements cover the period of peak wastewater disposal and seismicity rates and suggest an absence of significant temporal rotations in the local anisotropy and stress orientations associated with wastewater disposal.
Representación femenina en las campañas publicitarias de marcas deportivas=Female representation in advertising campaigns for sports brands
Authors: Sánchez-Labella Martín Inmaculada
Published: July 2021

ResumenEste artículo pretende conocer el modo en que las marcas deportivas más valoradas, según el Informe BrandZ 2020, han representado o representan a las mujeres en aquellas campañas enfocadas en incentivar los principios de igualdad en el ámbito deportivo. El análisis de las campañas de Nike, Adidas, Under Armour y The North Face muestra que estas recurren a los valores de superación, diversidad y libertad, y lo hacen sin representaciones estereotipadas. Aunque se percibe un compromiso con la igualdad en el deporte, de las representaciones y el mensaje publicitario se extraen connotaciones sexistas. Salvo en el caso de la campaña Now is her time (Adidas), las otras representan la lucha por la igualdad como una tarea exclusiva de las mujeres.AbstractThis article aims to find out how the most valued sports brands, according to the BrandZ 2020 Report, have represented or represent women in those campaigns focused on promoting the principles of equality in the sports field. The analysis of the campaigns of Nike, Adidas, Under Armour and The North Face shows that they draw on to the values of personal improvement, diversity and freedom, and they do so without stereotyped representations. Although a commitment to equality is perceived, sexist connotations are extracted from the representations and the advertising message. Except in the case of “Now is her time” (Adidas’s campaign), the other brands represent the fight for equality as an exclusive task of women.
Aceptación de mitos sobre agresión sexual en universitarios colombianos=Acceptance of myths about sexual agression among Colombian university students
Authors: Zakzuk-López Sharick , Vázquez-Miraz Pedro
Published: July 2021

ResumenLa presente investigación estudia la relación entre la aceptación de mitos sobre la agresión sexual en estudiantes de una universidad colombiana. Es un estudio de alcance correlacional con un diseño no experimental transversal en el que participaron 176 estudiantes, escogidos por medio de un muestreo no probabilístico por conveniencia. Se aplicó, de manera presencial y virtual, el instrumento Acceptance of Modern Myths about Sexual Aggression (AMMSA) en su adaptación al español. Se concluyó que existen diferencias significativas entre las variables sexo y facultad con los resultados en la prueba, siendo los hombres e ingenieros quienes mostraron una mayor normalización de situaciones sexualmente violentas.AbstractThe following investigation studies the relationship between the acceptance of myths about sexual aggression among students at a Colombian university. The study has a correlation scope with a non-experimental cross-sectional group comparison design, in which 178 students were involved. The Acceptance of Modern Myths about Sexual Aggression scale (AMMSA), adapted into Spanish, was applied directly and virtually. As a result, this study has demonstrated the significant differences between the sex and faculty variables and the results of the test, in which the males and engineers showed a greater normalization of sexually violent situations.
Análisis desde la perspectiva de género del engagement de los principales youtubers de divulgación científica=Analysis of the engagement of the main popular science youtubers from a gender perspective
Authors: Cambronero-Saiz Belén , Segarra-Saavedra Jesús , Cristófol-Rodríguez Carmen
Published: July 2021

ResumenLa participación de las mujeres en YouTube es menor que la de los hombres, tanto en forma de audiencia como produciendo y divulgando contenidos. A través del análisis de los principales youtubers científicos españoles diferenciados por género, esta investigación calcula sus tasas de engagement (likes, dislikes y comentarios) y su alcance en términos de visualizaciones, así como el tipo de materia abordada en cada caso. Se evidencia que los hombres copan los canales científicos en YouTube, que mayoritariamente proceden de disciplinas STEM, siendo más productivos y obteniendo mayor alcance, seguimiento e impacto. Sin embargo, a pesar de que los videos conducidos por mujeres tienen menos suscriptores y visualizaciones, todos ellos tienen un mayor número de interacciones y mayor engagement comportamental. AbstractThe participation of women on YouTube is lower than men, both in terms of audience and in terms of producing and disseminating content. Through the analysis of the main Spanish scientific youtubers differentiated by gender, this research calculates their engagement rates (likes, dislikes and comments) and their reach in terms of views, as well as the type of subject matter addressed in each case. It shows that men dominate science channels on YouTube, which are mostly from STEM disciplines, being more productive and obtaining greater reach, follow-up and impact. However, despite the fact that the videos led by women have fewer subscribers and views, they all have a higher number of interactions and greater behavioral engagement.
El rol del audiovisual en la activación de la memoria autobiográfica en víctimas de violencia de género=The role of audiovisual in the activation of autobiographical memory in victims of gender violence
Authors: Sainz de Baranda Andújar Clara , Blanco-Ruiz Marian , San Segundo Rosa
Published: July 2021

ResumenEl objetivo de este artículo es catalogar los recursos audiovisuales que reflejan las situaciones de violencia contra las mujeres, siendo éstos capaces de activar la memoria autobiográfica de las víctimas. Se han realizado entrevistas semiestructuradas a 59 profesionales que trabajan con víctimas de violencia de género, se abordan estos relatos de las profesionales que utilizan recursos audiovisuales en su trabajo con las víctimas de violencia de género. Su discurso, como informantes clave, se ha analizado con Atlas.ti.v.8. Los 138 títulos audiovisuales muestran una gran heterogeneidad, con representación de las múltiples violencias que sufren las mujeres. Incorporar estos nuevos recursos posibilitarán enseñar a las máquinas emociones específicas derivadas de la experiencia traumática que supone la violencia de género.AbstractThe aim of this article is to catalogue the audiovisual resources that reflect situations of violence against women, which can activate the autobiographical memory of the victims. The methodology used is based on semi-structured interview with 59 professionals who work with victims of gender violence. Their discourse was analysed with Atlas.ti.v.8. The 138 titles mentioned show a great heterogeneity in the audiovisuals, with a representation of the multiple forms of violence suffered by women, beyond the intimate partner or ex-partner. Incorporating these new resources will make it possible to teach the machines specific emotions derived from the traumatic experience of gender-based violence.
Percepción de las profesionales de la publicidad sobre la igualdad laboral en su sector=Women working in advertising and their perceptions about the equality in this sector
Authors: Buitrago Álex , Martín García Alberto
Published: July 2021

ResumenUn porcentaje de las plantillas de las agencias de publicidad y los departamentos de comunicación de las marcas está conformado por mujeres graduadas y licenciadas en titulaciones de Ciencias de la Comunicación. El objeto de esta investigación reside en conocer cuál es su percepción acerca de la posición que ocupan, así como de las dificultades que se encuentran para acceder a puestos de responsabilidad y ascender en el organigrama empresarial. Los resultados revelan que el sector de la publicidad sigue sin estar vertebrado desde la igualdad. Entre otros aportes, los datos indican que, ante ciertas situaciones laborales como la posibilidad de un ascenso, las mujeres perciben que deben hacer méritos superiores a los hombres para alcanzar puestos similares.AbstractAdvertising agencies and brands are formed by women graduates in studies belonging to Communication Sciences. Through this research, we aim to give these women a voice and find out first-hand what their perception is about the position they occupy, as well as the difficulties they encounter entering into a profession and moving up the organisation chart of the company they represent. The results indicate that we are dealing with an issue that has not been solved from an equality point of view, revealing that, in certain work situations, such as the possibility of promotion, women mostly have the perception that they have to do better than men in order to reach the same position.
Impact of the COVID-19 Pandemic on Ophthalmic Practice. Historical Aspects and Clinical Examples
Authors: Trubilin V. N. , Poluninа E. G. , Kurenkov V. V. , Andzhelova D. V. , Kazaryan E. E. , Markova E. Yu. , Chinenova K. V. , Evstigneeva Yu. V.
Published: July 2021

This article presents data on clinical ophthalmological manifestations of COVID-19 described in the literature, clinical examples that we met in pandemic conditions, COVID-19 including early and late manifestations, as well as references to studies conducted decades ago and aimed to evaluate the effects of coronavirus infection on the visual organ. The purpose of the most studies was to study the effect of COVID-19 on the visual organ indicate that the most common ophthalmological manifestation of this disease is conjunctivitis, which occurs in 3–10 % of cases. Our observations showed that patients with COVID-19, when applying for an appointment with an ophthalmologist after 1–3 months, make complaints about the feeling of dryness, discomfort in the eyes, itching and redness of the eyelids. These complains arose immediately after the illness and persisted during the above terms. This phenomenon can be explained by the fact that any inflammatory process occurring on the eye surface disrupts the process of lacrimation and leads to the emergence of dry eye syndrome. It is necessary to pay close attention to complaints from the visual organ not only in patients with COVID-19 in the early stages of the disease, but also in the coming months after stopping the acute pathological process. As studies have shown, coronavirus can involve the posterior segment of the eye in the pathological process, since this virus has a retinotropic effect. This hypothesis can be confirmed by the reports of several authors who studied with optical coherence tomography (OCT) the state of the retina 11–33 days after the onset of symptoms in patients with COVID-19. OCT data indicate the presence of hyperreflexive zones at the level of the ganglion cell layer and the plexiform layer, the severity of these zones being greater in the papillomacular bundle region. In addition, cases of thromboembolic complications affecting the vascular system of the eye are described. Considering the fact that in the development of thromboembolism of the central artery and retinal vein, therapy is as effective as possible in the first hours from the beginning of this pathological process development, close attention should be paid to patients’ complaints to visual impairment occurred against the background of coronavirus infection. The data presented in this article open up a range of possibilities for conducting new scientific research that will help to preserve the vision and health of our patients as effectively as possible.
Dendritic Branching of Retinal Ganglion Cells as a Biomarker of Glaucomatous Optic Neuropathy and Alzheimer’s Disease and a Target of Neuroprotective Therapy
Authors: Zueva M. V. , Zhuravleva A. N. , Bogolepova A. N.
Published: July 2021

Irreversible damage to the structure of axons and death of the retinal ganglion cell (RGC) soma in primary open-angle glaucoma (POAG) and Alzheimer’s disease (AD) develop against the background of the already existing clinical manifestation, which is preceded by a slow period of progressive loss of synapses and dendrites of the RGCs. Recent studies have shown that the integrity of the RGC’s dendritic branching can serve as both a target of neuroprotective therapy and a sensitive marker of retinal degeneration in AD and glaucoma. To develop methods of complex neuroprotective therapy, it is necessary to substantiate the targets and tactics of affecting the dendritic tree of the RGCs, the remodeling of which, according to modern concepts, can be closely and antagonistically related to the regeneration of the axon after its damage in trauma and neurodegenerative diseases. RGCs are highly capable of functional modification. Currently, it has been proven that the use of neuroprotective drugs and neurotrophins is promising for maintaining the adaptive plasticity of RGCs and restoring their synaptic contacts at the level of the retina and brain. Understanding the features of the adaptive plasticity of RGCs in AD and glaucoma will make possible to use technologies to activate the internal potential of neuronal remodeling, including the modification of dendritic branching of RGCs and regeneration of their axons, in the preclinical stages of these diseases. Increasing knowledge about the sequence and mechanisms of early events in the retina’s inner plexiform layer will contribute to the development of targeted neuroprotective therapy and new technologies to detect early POAG, AD, and, possibly, other systemic and local neurodegenerative conditions.
New Qualitative Methods for Assessing the “Fluid” in the Retina in Age-Related Macular Degeneration
Authors: Budzinskaya M. V. , Plyukhova A. A.
Published: July 2021

Age-related macular degeneration (AMD) is a chronic disease of the central retina and one of the main causes of blindness in patients over 60 years of age in industrialized countries. Currently, anti-vascular endothelial growth factor therapy (anti-VEGF therapy) has become the standard of neovascular AMD treatment, leading to the prevention of progressive vision loss in more than 90 % of treated patients during a two-year follow-up period. In the modern world there are transition from quantitative assessment of “fluid” according to optical coherence tomography (OCT) — the thickness of the central retinal zone, to qualitative — the presence of IRF, SRF, fluid under RPE. The data obtained by Zinkernagel have shown that, despite good functional results (an increase in visual acuity), the administration of the drug once every 2 months leads not only to fluctuations in IRF and SRF, but also to serous PED [4]. The existing qualitative and quantitative analysis is not perfect. Fluctuation is a new qualitative marker of the study of disease activity, it is defined as the sum of all types of fluid (IRF + SRF + fluid under RPE) in a certain time interval (with monthly measurement of the indicator). The fluctuation index was determined from the cumulative change in the thickness of the retina in the fovea over time [6]. Thus, the fluid is considered as a key morphological criterion for the activity of nVMD and an indication for (initiation or continuation) of antiangiogenic therapy. At the same time, there is evidence that a lower level of each type of fluid (IRF, SRF, fluid under RPE) is associated with better BCVA results against the background of anti-VEGF therapy [17]. The stability of retinal thickness during anti-VEGF therapy is no less important parameter than the statement of fluid resolution at a certain time, and it appears that better control of the central retinal thickness was associated with higher overall NEI VFQ-25 scores and individual scales reflecting important daily activities of the patient [16].
Effect of Hemodialysis on Diabetic Retinopathy
Authors: Vorobyeva I. V. , Pinchuk A. V. , Bulava E. V. , Lazareva K. E. , Zhuravel N. S.
Published: July 2021

Diabetes mellitus is a serious health problem in both developed and developing countries. It is expected that by 2040 the incidence of diabetes mellitus in the world will increase to 642 million people. With the increase in the incidence of diabetes mellitus, the incidence of diabetic vascular complications increases, which worsen the quality of life of patients and triple the risk of death. Diabetic retinopathy is one of the most common microvascular complications of diabetes mellitus, leading to progressive loss of visual function. Diabetic retinopathy occurs in conjunction with diabetic nephropathy. This fact is associated with the anatomical similarity of the blood-retinal barrier and the glomerular filtration barrier, as well as with the general pathogenetic mechanisms of the effect of hyperglycemia on peripheral microcirculation. On average, after 10–15 years, patients with decompensated diabetes mellitus develop end-stage renal failure, requiring renal replacement therapy, such as peritoneal dialysis, programmed hemodialysis, and kidney transplantation. This article highlights the latest data on the effect of programmed hemodialysis on the morphofunctional state of the retina in patients with diabetes mellitus.
First Clinical Results of Modular Intraocular Lens Implantation
Authors: Batkov E. N. , Artemyeva T. F. , Pashtayev N. P. , Pozdeyeva N. A.
Published: July 2021

Introduction. Recent population studies reveal steady growth in intraocular lens (IOL) exchanges including those for refractive and other optical reasons. To lower complication risks related to IOL exchange, we introduced a modular IOL model with replaceable optical part.

Purpose: preliminary analysis of modular IOL implantation clinical results.

Patients and methods. From August 2018 to February 2020, five patients as part of their surgical treatment for various forms of cataract received newly designed modular IOLs. The modular IOL is composed of two separate parts — haptic and optic, manufactured from the same elastic acrylic material with hydrophobic properties. The haptic includes a closed ring and a pair of open equally distant loops in a unified design. The haptic ring with projections serves as a base for optical disk. The current study evaluated characteristics of the IOL implantation and assembly process, as well as possible development of intra- and early postoperative complications.

Results. First implantations of the modular IOL accomplished using standard surgical instrumentation and disposables passed without complications. We did not observe scratches, breaks or any other mechanical damage to neither haptic, nor optical parts. During simultaneous implantation, optical disks fixated in haptic rings preserved their due positioning after transiting through slender injector channel. There were no specific, modular-IOL related complications in the early postoperative period. The optical disk maintained correct location, delimited by fixation leaflets of the haptic ring.

Conclusion. Early results for clinical application of the novel modular IOL demonstrated feasibility of its safe implantation in disassembled and preassembled modes.
Results of Using Different Modes of Presentation of Stereostimuli in the Study of Stereo Vision in Normal Children and in Children with Non-Paralytic Strabismus without Functional Scotoma
Authors: Rychkova S. I. , Likhvantseva V. G.
Published: July 2021

The work is devoted to one of the actual problems of current ophthalmology — creating effective methods of studying stereovision.

The purpose — comparative analysis of the capability of stereoperception under conditions of using different regimes of alternating presentation of stereo stimuli with different characteristics in children with strabismus and in children without ophthalmopathology.

Patients and methods. 294 school children — 167 children of the control group (without ophthalmopathology) and 127 children with non-paralytic strabismus without functional scotoma (FSS) were observed. We used stereostimuli with different characteristics in the following regimes of presentation: 1) the regime of simple monocular alternating (alternate presentation of an image for the right and left eye); 2) the regime having an “empty” interval (black background) between monocular phases; 3) the regime having a binocular phase (a binocular image containing details corresponding to the stimuli for the right eye and the left eye) between monocular phases.

Results. It was found that the majority of children with non-paralytic strabismus, who are incapable of stereoperception with the classic Fly-test and Lang-test, can perceive the stereoeffect with alternating presentation of stereostimuli within individual ranges of durations of monocular phases, a binocular phase and an “empty” interval. In children of the control group when switching from the simple alternation regime to the “empty” interval regime the maximal durations of monocular phases, which preserved the stereoeffect, decreased and when switching to the binocular phase regime they significantly increased. In children with strabismus linear images are simpler for stereoperception than random-dot images as well as in children of the control group (p < 0.001); stimuli creating the effect of the frontoparallel separation of details get perceived better than those creating the decline effect or the turning effect (p < 0.001); stimuli creating the effect of the vertical stripes decline get perceived better than those creating the effect of the horizontal stripes turning (p < 0.001). However, as opposed to the children of the control group, in children with strabismus the stereoeffect gets formed better under conditions of the peripheral localization of linear details than under conditions of the central one.

Conclusion. Using computer programs with different regimes of alternating presentation of stereostimuli with certain characteristics allows to effectively evaluate individual capability of stereoperception which is necessary for the personalized approach to the selection of visual stimuli and stimuli presentation regimes in functional treatment of patients with non-paralytic strabismus.
New Drugs for Ophthalmology Based on 6-methyl-3-(thietan-3-yl)uracil (Experimental Research)
Authors: Gabdrakhmanova A. F. , Mesheryakova S. A. , Kifldiyarov F. Kh. , Kurbanov S. A.
Published: July 2021

Purpose: develop of new drugs for ophthalmology based on 6-methyl-3-(thietan-3-yl)uracil and methyluracil.

Materials and methods. An experimental study was carried out on 10 rabbits with a body weight of 3.5–4.0 kg of chinchilla breed. A thermal burn of the cornea in the eyes of 6 rabbits and a chemical burn of the cornea in the eyes of 4 rabbits were modeled. Therapy with the use of drugs was carried out: ophthalmic ointment — in thermal burns, ophthalmic medicinal films based on 6-methyl-3-(thietan-3-yl)uracil and methyluracil in chemical burns.

Results. The use of ophthalmic ointment based on 6-methyl-3-(thietan-3-yl)uracil for thermal burns led to a decrease in conjunctival hyperemia and resorption of corneal edema by 4–5 days. On the 14th day of therapy, the microscopic picture of the rabbits cornea had the usual normal structure. The use of 6-methyl-3-(thietan-3-yl)uracil and methyluracil based ophthalmic drug films yielded the following results: centripetal epithelialization of corneal erosion was observed, epithelial regeneration was higher with the use of methyluracil eye drug films and total epithelization was achieved on the 7th day of observation than when using eye drug films based on 6-methyl-3-(thietan-3-yl)uracil, where total epithelization occurred on the 14th day. Complete restoration of the surface epithelial layer of the cornea in both groups was observed on the 21st day.

Conclusions. The use of new drugs based on 6-methyl-3-(thietan-3-yl)uracil and methyluracil in various types of corneal burns showed good tolerance in the eyes of experimental animals, shortened the treatment time, and achieved high wound healing efficacy.
Our Experience Olopatadine Treatment of Allergic Conjunctivitis in Children
Authors: Vorontsova T. N. , Zaitseva M. V. , Chramtsova M. A.
Published: July 2021

The authors analyzed the treatment results of 53 patients (106 eyes) with allergic conjunctivitis. All patients received Olopatadine 0.2 % (Visallergol) in drops once a day during 1 month. All patients underwent the same tests: scraping from the conjunctiva for the presence of eosinophils, evaluation of the inflammation symptoms using 4-ball scale, biomicroscopy of cornea and conjunctiva with staining by lissamine green and tear film stability (Norn’s method). All of the above-mentioned tests were performed before the treatment, on 14-th day and after the course of therapy. The inflammatory reaction of conjunctiva, the amount of discharge in the conjunctival cavity and the staining of the conjunctiva with lissamine green decreased in all patients starting from the 14-th day of treatment. The maximal effectiveness of the drop was registered in patients with the chronic type of allergic conjunctivitis. The manifestation of the disease reduced significantly after 1 month of treatment, but it does not disappear completely. So it is necessary to continue therapy after 1 month. The laboratory methods of diagnosis confirm the effectiveness of Visallergol by disappearance of eosinophils in the conjunctiva scrapings. The secondary dry eye syndrome developed in all types of the allergic conjunctivitis and needs a long-term treatment. The maximal intensity of dry eye syndrome was registered in patients with chronic type of the allergic conjunctivitis. The drop can be used starting from 2 years old.
Sequential anticancer therapy in a patient with metachronous primary uterine cancer and breast cancer
Authors: Sultanbaev A.  V. , Nasretdinov A.  F. , Sultanbaeva N.  I. , Menshikov K.  V. , Musin Sh.  I. , Izmailov A.  A. , Lipatov O.  N. , Pushkarev V.  A. , Valiakhmedov R.  B. , Pushkarev A.  V. , Mufazalov F.  F.
Published: July 2021

Breast cancer (BC) is a heterogeneous disease characterized by the presence or absence of membrane receptor overexpression on tumor cells that correlates with the disease prognosis. Understanding of the patterns and mechanisms of tumor progression gained through clinical experience of managing BC patients is important. The treatment strategy depends on the hormone receptor status of the tumor, the HER2 / neu expression, and the proliferative activity level. A clinical case of advanced luminal A breast cancer is reported, and the rationale for sequential treatment strategy is provided taking into account the clinical situation and clinical course of the disease. Adequate endocrine therapy for hormone-positive metastatic BC provides long-term tumor control like in this case, as well as a high quality of life over the entire course of sequential treatment with anticancer drugs.
Nivolumab: 5 years from the day of international registration of immunotherapy of metastatic kidney cancer
Authors: Tsimafeyeu I. V.
Published: July 2021

Five years ago, on November 23, 2015, the US Food and Drug Administration (FDA) approved nivolumab for the treatment of metastatic renal cell carcinoma, thus ushering in a new era of immunotherapy for this tumor. The purpose of this review is to systematize the accumulated results of studies of nivolumab in monotherapy and in combinations.
On Trying to be With Each Other: A Conversation Between Laura Vriend and Nichole Canuso
Authors: Vriend Laura , Canuso Nichole
Published: July 2021

No abstract available.
Screendance Festivals and Online Audiences
Authors: Bench Harmony , Christa Gabri , Guadarrama Yolanda M. , Hagan Cara , Hargraves Kelly , Hayes Marisa
Published: July 2021

No abstract available.
Editorial: This Is Where We Dance Now
Authors: Bench Harmony , Harlig Alexandra
Published: July 2021

No abstract available.
Multi Parametric Method for the Objective Acoustic Evaluation of the Voice Produced by Laryngectomy Patients
Authors: Kabache Mahraz , Guerti Mhania
Published: July 2021

A reliable perceptive analysis implying several sessions of listening turns out to be consuming in time and in human resources, and therefore not allowing a regular use in clinical practice. At the level of the Ear, Nose and Throat (ENT) services the rehabilitative speech therapist is in charge of estimating by listening to the quality of the voice, which entraines a non reliable perceptive evaluation compared with the one that will be proposed in this work. In this study, objective instrumental approaches based on physical measures has been proposed. These approaches allowing the analysis and estimation of the acoustic characteristics of the voice of the patients having a total laryngectomy. The results are compared with those obtained in a healthy vocal speaker. The outcomes indicate that objective evaluations can provide a homogeneous database for a better interpretation of articulators and vocal dysfunctions.
Monitoring of Photovoltaic Performance as an Alternative Energy Source in Campus Buildings
Authors: Sunanda Wahri , Tiandho Yuant , Gusa Rika Favoria , Darussalam Muhammad , Novitasari Dwi
Published: July 2021

Universitas Bangka Belitung is currently supplied by electricity from the State Electric Company in 690 kVA. Concerning utilizing renewable energy at Universitas Bangka Belitung, the solar power plant is an alternative energy source that will implement. Therefore it is necessary to design a solar power plant with a monitoring system to be known at any time the performance of the solar power plant. Monitoring is conducted in real-time via a website displaying several photovoltaic parameters, including voltage, current, humidity, temperature, and solar irradiation. From the measurement results obtained environmental parameters for temperature between 26°- 56.4°C, humidity 23.6% RH - 85.6% RH and solar irradiation 4.4 W/m2 - 1281.4 W/m2. The measured voltage of 11.41 - 18.95 volts with the rated current from the load used is 0.05 - 1.5 amperes.
Combining Work and Pension in Norway: Gathering Information and Imagining the Future
Authors: Grødem Anne Skevik , Kitterød Ragni Hege
Published: July 2021

The Norwegian pension system has provided unprecedented flexibility to combine work and pension drawing from the age of 62, and this has become a popular option. Using qualitative interviews with 28 older workers, we explore their information strategies and motivations. We find that many informants struggle to understand the various options and their consequences and use different strategies to shield themselves from insecurity: they downplay the issue or point to factors beyond their control. Two key motives for early pension take-up are the desire to secure the money for one’s family in the event of early death and to get the money while still vigorous. Informants typically imagine life after 80 as quiet and with fewer material demands. In conclusion, the analysis shows how adaptations to the flexible pension system are embedded in notions of ageing, institutional trust, and a newfound sense of ownership regarding one’s retirement savings.
Strengthening of oil exporters’ position within OPEC+ in the world oil market
Authors: Chuvakhina Larisa G. , Moldenhauer Nikolai A. , Nasirbeik Anahita
Published: July 2021

No Abstract.
Planned redesign of beehive coke ovens for pollution control and power generation
Authors: Kumar Samanta Binay , Kumar Jain Manish
Published: July 2021

Fossil fuel based thermal power or ovens not only exude greenhouse gases and pollutants but transfer enormous amount of waste heat up in air. Heat gets enveloped in the stratosphere and circulate around the earth; escalating global warming. France, Czech Republic, Slovakia, Austria, Andorra, Luxembourg, Poland and Germany made it the hottest June on record in 2019. Around 50 coke ovens around Dhanbad are losing and facing closure, with fate of employees doomed. Jharkhand State Pollution Control Board, Dhanbad had been issuing letters to the small-scale refractory and beehive hard coke-ovens to bring down stack gas emissions to below 150mg/Nm3 of suspended particulate matter (SPM), equivalent to the standards of large thermal power plants, deploying electrostatic precipitators (ESP). Some locally made pollution control devices were deployed, but these reduced the chimney draft and coking time increased. Installation of wet scrubbing methods would not be economic and slow down production. With experience as the Manager of a by-product coke oven, the chimney detour method with mechanical exhauster suggested for beehive coke oven. Proposed design not only can generate power, but also trap pollutants by a kind of wet scrubbing and produce byproducts like coal tar. Various associations of small-scale hard coke ovens and refractory industries had approached The Institution of Engineers (India), Dhanbad Local Centre. In this paper, the authors briefly present how waste heat can be converted to power, while absorbing pollutants in hydraulic main in the unique chimney detour method and producing coal tar, exuding clean gas.
Adoption of mission critical communications in mines
Authors: Bhattacharya Jayanta
Published: July 2021

No Abstract.
A review on underground mine ventilation system
Authors: Haitham Kanam Omer , Obaid Ahmed Maher
Published: July 2021

In the field of mines, there are dozens of methods concerned with the optimization of ventilation system in underground mines and how bad ventilation system is playing a major effect on miners and mine’s activities. The ventilation system is considered very important because it consumed high energy of mines of total power consumption. This paper is a review of previous studies, which have been done before on design of ventilation system and its optimization methods like, using of software tools to simulate the numerical equations based on the pressure, temperature, flow rate, and other effected parameters, which are recorded by various ways of surveying. It has observed that Ventsim software is widely used because of its flexibility in dynamic simulation based on various parameters included deep, fan position and flow rate.
Why ground penetrating radar (GPR) should be allowed for testing in the mines
Authors: Bhattacharya Jayanta
Published: July 2021

No Abstract.
How to induct and adopt automation in the minerals, oil and gas sector
Authors: Bhattacharya Jayanta
Published: July 2021

No Abstract.
Research on solar water heating system based on TRNSYS simulation optimization
Authors: Yan Yan , Zhang Liyan , Li Yuhan , Xu Xiangyu , Jiang Zhencheng , Cheng Feiyu
Published: July 2021

In this paper, the typical system of solar energy system: natural circulation system and forced circulation system are analyzed. The two systems are simulated on the TRNSYS platform, and the configuration of the system itself has been discussed. The purpose is to provide reference for the scientific implementation of solar energy architecture integration. On the basis of summarizing the solar energy construction technology, the natural circulation system and the forced circulation system of solar hot water system have been discussed emphatically. The simulation experiment is designed on the TRNSYS platform. The influence of different heat collection area and water tank volume on solar energy guarantee rate and system efficiency has been discussed by simulation data. Finally, the optimal allocation scheme of natural constraints of natural circulation and forced circulation has been obtained.
Underground communication is keeping pace with surface communication
Authors: Bhattacharya Jayanta
Published: July 2021

No Abstract.
High angle conveying in opencast mines can be green, efficient, economic and flexible
Authors: Kumar Bag Shyamal
Published: July 2021

No Abstract.