bluuebunny/crossref_metadata_2025 huggingface dataset:
Resting State EEG Correlates of Suicide Ideation and Suicide Attempt
Authors: Amico Francesco , Frye Richard E. , Shannon Scott , Rondeau Steve
Published: May 2023

Suicide is a global phenomenon that impacts individuals, families, and communities from all income groups and all regions worldwide. While it can be prevented if personalized interventions are implemented, more objective and reliable diagnostic methods are needed to complement interview-based risk assessments. In this context, electroencephalography (EEG) might play a key role. We systematically reviewed EEG resting state studies of adults with suicide ideation (SI) or with a history of suicide attempts (SAs). After searching for relevant studies using the PubMed and Web of Science databases, we applied the PRISMA method to exclude duplicates and studies that did not match our inclusion criteria. The selection process yielded seven studies, which suggest that imbalances in frontal and left temporal brain regions might reflect abnormal activation and correlate with psychological distress. Furthermore, asymmetrical activation in frontal and posterior cortical regions was detected in high-risk depressed persons, although the pattern in the frontal region was inverted in non-depressed persons. The literature reviewed suggests that SI and SA may be driven by separate neural circuits and that high-risk persons can be found within non-depressed populations. More research is needed to develop intelligent algorithms for the automated detection of high-risk EEG anomalies in the general population.
Radiotherapy and Chemotherapy Features in the Treatment for Locoregional Recurrence of Endometrial Cancer: A Systematic Review
Authors: Ronsini Carlo , Iavarone Irene , Reino Antonella , Vastarella Maria Giovanna , De Franciscis Pasquale , Sangiovanni Angelo , Della Corte Luigi
Published: May 2023

Radiation therapy (RT) is the standard of care in patients with locoregional or isolated vaginal recurrence who never underwent irradiation. It is often associated with brachytherapy (BT), whereas chemotherapy (CT) is a rare treatment option. We systematically searched the PubMed and Scopus databases in February 2023. We included patients with relapsed endometrial cancer, describing the treatment of locoregional recurrence, and reporting at least one outcome of interest—disease-free survival (DFS), overall survival (OS), recurrence rate (RR), site of recurrence, and major complications. A total of 15 studies fulfilled the inclusion criteria. Overall, 11 evaluated RT only, 3 evaluated CT, and 1 analyzed oncological outcomes after administration with a combination of CT and RT. In total, 4.5-year OS ranged from 16% to 96%, and DFS ranged from 36.3% to 100% at 4.5 years. RR ranged from 3.7% to 98.2% during a median follow-up of 51.5 months. Overall, RT showed a 4.5-year DFS from 40% to 100%. CT revealed 36.3% DFS at 4.5 years. RT showed a 4.5-year OS ranging from 16% to 96%, whereas CT revealed a 27.7% OS rate. It would be appropriate to test multi-modality regimens to evaluate outcomes and toxicity. EBRT and BT are the most employed options to treat vaginal recurrences.
Spatiotemporal Variation in Land Use and Ecosystem Services during the Urbanization of Xining City
Authors: Wei Jinpeng , Tian Ming , Wang Xia
Published: May 2023

Based on the five phases of land use data from Xining corresponding to 1980, 1990, 2000, 2010, and 2020, we used the equivalent factor method to analyze the values of spatial-temporal variation characteristics of land use and ecosystem services in Xining. The results showed that (1) farmland and developed areas were the most active types of land, and the continuous occupation of farmland and developed areas led to the formation of a kind of “cross shape” in the spatial pattern of conversion of land use types along the Huangshui River, Beichuan River, and Nanchuan River from south to north and from northwest to southeast, respectively, with the central urban area serving as a core of the pattern; (2) the transformation between different land use types mainly occurred in the land-slope range between 0–15° and altitudes between 2000–2750 m; and (3) the ESV of Xining increased by RMB 2165.26 × 106 in the past 40 years. The period from 2000 to 2020 was the main growth period of the ecosystem service value of Xining. Urbanization had a great impact on the variation in land use types and the evolution of ecosystem service values. In the middle and late stages of urbanization, different types of land use changed significantly within each county and district. The ecosystem service values of the central districts were low, with those of the marginal districts and counties being higher, forming a “core-periphery” trend and a phenomenon of hollowing ESV. (4) The spatial agglomeration effect of the ESV per unit area was continuously enhanced in Xining. The high-high (slope-altitude) type of area was distributed in the north and west of Xining, whereas the low-low type of area was distributed in the urban area at the intersection of major rivers in the southeast of Xining.
The Role of ECG Strain Pattern in Prognosis after TAVI: A Sub-Analysis of the DIRECT Trial
Authors: Drakopoulou Maria , Oikonomou Georgios , Apostolos Anastasios , Karmpalioti Maria , Simopoulou Chryssa , Koliastasis Leonidas , Latsios George , Synetos Andreas , Benetos Georgios , Trantalis George , Sideris Skevos , Dilaveris Polychronis , Tsioufis Costas , Toutouzas Konstantinos
Published: May 2023

Background: The presence of an electrocardiographic (ECG) strain pattern—among other ECG features—has been shown to be predictive of adverse cardiovascular outcomes in asymptomatic patients with aortic stenosis. However, data evaluating its impact on symptomatic patients undergoing TAVI are scarce. Therefore, we tried to investigate the prognostic impact of baseline ECG strain pattern on clinical outcomes after TAVI. Methods: A sub-group of patients of the randomized DIRECT (Pre-dilatation in Transcatheter Aortic Valve Implantation Trial) trial with severe aortic stenosis who underwent TAVI with a self-expanding valve in one single center were consecutively enrolled. Patients were categorized into two groups according to the presence of ECG strain. Left ventricular strain was defined as the presence of ≥1 mm convex ST-segment depression with asymmetrical T-wave inversion in leads V5 to V6 on the baseline 12-lead ECG. Patients were excluded if they had paced rhythm or left bundle branch block at baseline. Multivariate Cox proportional hazard regression models were generated to assess the impact on outcomes. The primary clinical endpoint was all-cause mortality at 1 year after TAVI. Results: Of the 119 patients screened, 5 patients were excluded due to left bundle branch block. Among the 114 included patients (mean age: 80.8 ± 7), 37 patients (32.5%) had strain pattern on pre-TAVI ECG, while 77 patients (67.5%) did not exhibit an ECG strain pattern. No differences in baseline characteristics were found between the two groups. At 1 year, seven patients reached the primary clinical endpoint, with patients in the strain group demonstrating significantly higher mortality in Kaplan–Meier plots compared to patients without left ventricular strain (five vs. two, log-rank p = 0.022). There was no difference between the strain and no strain group regarding the performance of pre-dilatation (21 vs. 33, chi-square p = 0.164). In the multivariate analysis, left ventricular strain was found to be an independent predictor of all-cause mortality after TAVI [Exp(B): 12.2, 95% Confidence Intervals (CI): 1.4–101.9]. Conclusion: Left ventricular ECG strain is an independent predictor of all-cause mortality after TAVI. Thus, baseline ECG characteristics may aid in risk-stratifying patients scheduled for TAVI.
Selection of Operation Conditions for a Batch Brown Seaweed Biosorption System for Removal of Copper from Aqueous Solutions
Authors: Hansen Henrik K. , Gutiérrez Claudia , Valencia Natalia , Gotschlich Claudia , Lazo Andrea , Lazo Pamela , Ortiz-Soto Rodrigo
Published: May 2023

Heavy metal exposure from wastewater is an important environmental issue worldwide. In the search for more efficient treatment technologies, biosorption has been presented as an alternative for contaminant removal from wastewaters. The aim of this work is to determine the operation parameters of copper adsorption followed by biosorbent regeneration. The algae Durvillaea antarctica and Lessonia trabeculata were used as biosorbents in batch experiments. These biosorbents were exposed to different conditions, such as pH, copper concentration, exposure time, mass-to-volume ratios and regeneration reagents. Batch sorption tests revealed an adequate pH of 4.5–5.0. The selected biosorbent was D. antarctica due to a considerably higher copper retention capacity. As a regenerating reagent, sulfuric acid was more efficient. For diluted copper solutions (10 to 100 mg L−1), a biosorbent particle size of between 1.70 and 3.36 mm showed better retention capacity than larger particles and a biosorbent mass-to-volume ratio of 10 g L−1 was desirable for these metal concentrations.
Recent Progress in Porphyrin/g-C3N4 Composite Photocatalysts for Solar Energy Utilization and Conversion
Authors: Chen Sudi , Wei Jiajia , Ren Xitong , Song Keke , Sun Jiajie , Bai Feng , Tian Shufang
Published: May 2023

Transforming solar energy into chemical bonds is a promising and viable way to store solar energy. Porphyrins are natural light-capturing antennas, and graphitic carbon nitride (g-C3N4) is an effective, artificially synthesized organic semiconductor. Their excellent complementarity has led to a growing number of research papers on porphyrin/g-C3N4 hybrids for solar energy utilization. This review highlights the recent progress in porphyrin/g-C3N4 composites, including: (1) porphyrin molecules/g-C3N4 composite photocatalysts connected via noncovalent or covalent interactions, and (2) porphyrin-based nanomaterials/g-C3N4 composite photocatalysts, such as porphyrin-based MOF/g-C3N4, porphyrin-based COF/g-C3N4, and porphyrin-based assembly/g-C3N4 heterojunction nanostructures. Additionally, the review discusses the versatile applications of these composites, including artificial photosynthesis for hydrogen evolution, CO2 reduction, and pollutant degradation. Lastly, critical summaries and perspectives on the challenges and future directions in this field are also provided.
Purification of Natural Pigments Violacein and Deoxyviolacein Produced by Fermentation Using Yarrowia lipolytica
Authors: Nemer Georgio , Louka Nicolas , Rabiller Blandin Paul , Maroun Richard G. , Vorobiev Eugène , Rossignol Tristan , Nicaud Jean-Marc , Guénin Erwann , Koubaa Mohamed
Published: May 2023

Violacein and deoxyviolacein are bis-indole pigments synthesized by a number of microorganisms. The present study describes the biosynthesis of a mixture of violacein and deoxyviolacein using a genetically modified Y. lipolytica strain as a production chassis, the subsequent extraction of the intracellular pigments, and ultimately their purification using column chromatography. The results show that the optimal separation between the pigments occurs using an ethyl acetate/cyclohexane mixture with different ratios, first 65:35 until both pigments were clearly visible and distinguishable, then 40:60 to create a noticeable separation between them and recover the deoxyviolacein, and finally 80:20, which allows the recovery of the violacein. The purified pigments were then analyzed by thin-layer chromatography and nuclear magnetic resonance.
Molecular Confirmation of Accipiter Birds of Prey as Definitive Hosts of Numerous Sarcocystis Species, including Sarcocystis sp., Closely Related to Pathogenic S. calchasi
Authors: Šukytė Tautvilė , Butkauskas Dalius , Juozaitytė-Ngugu Evelina , Švažas Saulius , Prakas Petras
Published: May 2023

The present study aimed to test intestinal scrapings of the Northern Goshawk (Accipiter gentilis) and the Eurasian Sparrowhawk (Accipiter nisus) from Lithuania for S. calchasi and other Sarcocystis species characterised by bird–bird life cycles. The protozoan parasite Sarcocystis calchasi can cause respiratory and neurological diseases in a variety of birds; however, the distribution of this parasite is not well-examined. Sarcocystis species were identified with nested PCR and sequencing of the partial ITS1 region. Sporocysts and/or sporulated oocysts of Sarcocystis spp. were observed in 16 (100%) Northern Goshawks and 9 (56.3%) Eurasian Sparrowhawks. Four species, S. columbae, S. halieti, S. turdusi, and S. wobeseri, were confirmed in the Eurasian Sparrowhawk. Apart from the latter four species, S. calchasi, S. cornixi, S. kutkienae, and S. lari were established in the Northern Goshawk. A higher prevalence of Sarcocystis spp. and species richness in Northern Goshawks is associated with the differences in the diet of two examined Accipiter species. This study is the first report of S. calchasi in Lithuania. Furthermore, the genetically distinct species Sarcocystis spp. 23LTAcc, which is most closely related to S. calchasi, was found in three Northern Goshawks.
Looking at the Molecular Target of NS5A Inhibitors throughout a Population Highly Affected with Hepatitis C Virus
Authors: Ramos Diogo , Pinto Miguel , Sousa Coutinho Rodrigo , Silva Carolina , Quina Miriam , Gomes João Paulo , Pádua Elizabeth
Published: May 2023

Hepatitis C virus (HCV) is associated with liver damage and an increased progression rate to cirrhosis and hepatocellular carcinoma. In Portugal, it is prevalent in vulnerable populations such as injection drug users (IDU). HCV is characterized by a high intra-host variability, and the selecting driving forces could select variants containing resistance-associated substitutions (RAS) that reduce treatment effectiveness. The main goal of this study was to analyze the sequence variation of NS5A in treatment-naïve IDU. The epidemiological and clinical status of hepatitis C were analyzed, and samples were sequenced by Sanger and Next-Generation sequencing (NGS) to assess RAS and confirm HCV subtypes. Phylogenetic classification was concordant: 1a, 52.4%; 1b, 10.7%; 3a, 20.2%; 4a, 8.3%; 4d, 7.1%; and one 2k/1b recombinant. A 1a/3a mixed infection was detected by NGS. RAS were found in 34.5% (29/84) of samples using Sanger sequencing, while in 42.9% (36/84) using NGS. In sequences from subtypes 1a and 1b, RAS K24R, M28V, Q30H/R, H58D/P/Q/R, and RAS L31M and P58S were detected, respectively. In subtype 3a, RAS A30S/T, Y93H and polymorphisms in position 62 were identified. Additionally, RAS P58L was detected in genotype 4. The strategy used for the molecular survey of baseline HCV resistance is of particular importance to achieve treatment effectiveness and contribute to the elimination of hepatitis C.
Integrating BLUP, AMMI, and GGE Models to Explore GE Interactions for Adaptability and Stability of Winter Lentils (Lens culinaris Medik.)
Authors: Hossain Md. Amir , Sarker Umakanta , Azam Md. Golam , Kobir Md. Shahriar , Roychowdhury Rajib , Ercisli Sezai , Ali Daoud , Oba Shinya , Golokhvast Kirill S.
Published: May 2023

Lentil yield is a complicated quantitative trait; it is significantly influenced by the environment. It is crucial for improving human health and nutritional security in the country as well as for a sustainable agricultural system. The study was laid out to determine the stable genotype through the collaboration of G × E by AMMI and GGE biplot and to identify the superior genotypes using 33 parametric and non-parametric stability statistics of 10 genotypes across four different conditions. The total G × E effect was divided into two primary components by the AMMI model. For days to flowering, days to maturity, plant height, pods per plant, and hundred seed weight, IPCA1 was significant and accounted for 83%, 75%, 100%, and 62%, respectively. Both IPCA1 and IPCA2 were non-significant for yield per plant and accounted for 62% of the overall G × E interaction. An estimated set of eight stability parameters showed strong positive correlations with mean seed yield, and these measurements can be utilized to choose stable genotypes. The productivity of lentils has varied greatly in the environment, ranging from 786 kg per ha in the MYM environment to 1658 kg per ha in the ISD environment, according to the AMMI biplot. Three genotypes (G8, G7, and G2) were shown to be the most stable based on non-parametric stability scores for grain yield. G8, G7, G2, and G5 were determined as the top lentil genotypes based on grain production using numerical stability metrics such as Francis’s coefficient of variation, Shukla stability value (σi2), and Wrick’s ecovalence (Wi). Genotypes G7, G10, and G4 were the most stable with the highest yield, according to BLUP-based simultaneous selection stability characteristics. The findings of graphic stability methods such as AMMI and GGE for identifying the high-yielding and stable lentil genotypes were very similar. While the GGE biplot indicated G2, G10, and G7 as the most stable and high-producing genotypes, AMMI analysis identified G2, G9, G10, and G7. These selected genotypes would be used to release a new variety. Considering all the stability models, such as Eberhart and Russell’s regression and deviation from regression, additive main effects, multiplicative interactions (AMMI) analysis, and GGE, the genotypes G2, G9, and G7 could be used as well-adapted genotypes with moderate grain yield in all tested environments.
Use of Thermography to Evaluate Alternative Crops for Off-Season in the Cerrado Region
Authors: Silva Alberto do Nascimento , Ramos Maria Lucrecia Gerosa , Ribeiro Junior Walter Quadros , da Silva Patrícia Carvalho , Soares Guilherme Filgueiras , Casari Raphael Augusto das Chagas Noqueli , de Sousa Carlos Antonio Ferreira , de Lima Cristiane Andrea , Santana Charles Cardoso , Silva Antonio Marcos Miranda , Vinson Chistina Cleo
Published: May 2023

Future predictions due to climate change are of decreases in rainfall and longer drought periods. The search for new tolerant crops is an important strategy. The objective of this study was to evaluate the effect of water stress on the physiology and productivity of crops with potential for growing in the off-season period in the Cerrado, and evaluate correlations with the temperature of the canopy obtained by means of thermography. The experiment was conducted under field conditions, with experimental design in randomized blocks, in a split-plot scheme and four replications. The plots were: common bean (Phaseolus vulgaris); amaranth (Amaranthus cruentus); quinoa (Chenopodium quinoa); and buckwheat (Fagopyrum esculentum). The subplots were composed of four water regimes: maximum water regime (WR 535 mm), high-availability regime (WR 410 mm), off-season water regime (WR 304 mm) and severe water regime (WR 187 mm). Under WR 304 mm, the internal concentration of CO2 and photosynthesis were reduced by less than 10% in amaranth. Common bean and buckwheat reduced 85% in photosynthesis. The reduction in water availability increased the canopy temperature in the four crops and, in general, common bean was the most sensitive species, while quinoa had the lowest canopy temperatures. Furthermore, canopy temperature correlated negatively with grain yield, biomass yield and gas exchange across all plant species, thus thermal imaging of the canopy represents a promising tool for monitoring crop productivity for farmers, For the identification of crops with high water use management for research.
Phenolic Content, Antioxidant Capacity, and Browning Impact of Apple Slices during Microwave Drying: A Chemometric Approach
Authors: Soproni Vasile Darie , Bandici Livia , Teusdea Alin Cristian , Hathazi Francisc Ioan , Arion Mircea Nicolae , Molnar Carmen Otilia , Leuca Teodor , Dalea Claudia Andrada , Vicas Simona Ioana
Published: May 2023

Apples represent a category of products frequently consumed by people, owing both to their beneficial effects on human health and to their antioxidant effects. Microwave (MW) treatment is a simple and fast method that can be used successfully in the food industry to obtain dry apple slices, rich in bioactive compounds and with a pleasant aspect. This study presents the effect of applying microwave treating to apple slices from two cultivars (Golden Delicious and Idared), for three, four, and five minutes, respectively, at a power of 450 W, in order to reduce the browning effect. For this purpose, the browning index (BI), chromatic parameters (CIE L*a*b*), total phenolic content (Folin-Ciocâlteu method), and antioxidant capacity (by Ferric Reducing Antioxidant Power (FRAP assay) were evaluated in the case of apple slices before and after MW treatment. Based on the results obtained, it can be argued that the microwave treatment results in a significant increase in the total phenolic content and enhances antioxidant capacity in the case of both apple cultivars. Apples from the Idared cultivar have a higher total phenolic content than apples from the Golden cultivar, and this concentration increased by 56.14% and 48.9%, respectively, after MW treatment. In terms of antioxidant capacity, Idared apples also recorded a higher value compared to Golden cultivars. According to the results of the multivariate analysis, there are variations between the two apple categories with regard to the phenolic content and the browning process; browning was inhibited at the five-minute exposure to microwaves. The apple processing domain may use our findings in order to produce high-quality finished products, with a pleasant aspect, which retain the bioactive compounds of the fruit.
Bioherbicide from Azadirachta indica Seed Waste: Exploitation, Efficient Extraction of Neem Oil and Allelopathic Effect on Senna occidentalis
Authors: de Paulo Barbosa Larissa Macelle , Oliveira Santos Jorge , Mouzinho de Sousa Rayssa Carolinne , Barros Furtado Jomar Livramento , Vidinha Pedro , Suller Garcia Marco Aurelio , Aguilar Vitorino Hector , Fossatti Dall’Oglio Daiane
Published: May 2023

Bioherbicides are an alternative to minimize the damage caused to the environment using agrochemicals. This study had the objective of extracting neem oil from ripe waste fruits that Azadirachta indica A. Juss and optimizing the process using solvents (or a mixture of solvents) with different polarities. Then, through a solid-liquid extraction system (Soxhlet), the solvents hexane, methanol/hexane (1:1), ethanol, and hexane/ethanol (1:1) were used to determine the process with the highest yield and most efficiency. The physicochemical parameters of the extracted oil (density, acidity value, iodine value, saponification value, esters value, and molecular weight) and the % of free fatty acids were determined. In addition, the allelopathic properties of the oil (0%, 2%, 3%, and 4% m/v) on septic weed Senna occidentalis seeds were evaluated, analyzing their growth and development parameters (germination, germination speed, hypocotyl, and radicle length). Hexane was the most efficient (4 h) in neem oil extraction, with the highest yield (43%). It also provided a better oleic and linoleic acid content (41.3% and 18.6%), similar to ethanol extraction (41.1% and 20.22%). Moreover, the allelopathic properties were more prominent for the oils extracted with hexane and hexane/ethanol. This optimized process provides an efficient alternative to obtain a natural herbicidal potential for strategically controlling harmful plants.
The Status and Duties of Ecclesiastical Judges in Cases Concerning the Nullity of Marriage
Authors: Bzdyrak Grzegorz Marcin
Published: May 2023

The author discusses the status and duties of an ecclesiastical judge in processes concerning the declaration of nullity of marriage under canon law. The author addresses the requirements for candidates for the office of judge and highlights the changes introduced by the Motu Proprio Mitis Iudex Dominus Iesus in 2015. Next, the duties of the ecclesiastical judge in a matrimonial process are covered. First, the author points to the general duties and focuses on the most relevant ones. Second, the judge’s more specific duties are addressed. A major research problem investigated is who can be an ecclesiastical judge and what requirements the candidates must meet, both in the light of ecclesiastical and natural law. The author does not omit to discuss the origin of the power to judge and its consequences. The article cites papal speeches to the members of the Tribunal of the Roman Rota. They are a valuable source of guidance on exercising the power to judge. Special attention is paid to the ministry of the bishop as the first judge, as well as in light of the changes introduced by Pope Francis.
Haber-i Vâhid Yaklaşımının Kur'ân Yorumuna Etkisi
Authors: YILDIRIM Tuğba
Published: May 2023

Hz. Peygamber zamanında dînî konulardaki bilgiler, bizzat kendisinden alındığı için bu bilgilerin sorgulanmasına genellikle ihtiyaç duyulmamıştır. Ancak sonraki dönemlerde bu bilgilere rivayet ve nakil yoluyla ulaşılması, nakledilen haberlerin bilgi ve amel değerinin araştırılması gereğini doğurmuştur. Tevatür derecesine ulaşamamış haber olarak kabul edilen haber-i vâhidin, bilgi ve amel değeri tartışmalara konu olmuştur. Fıkıh, hadis ve kelâm ilimleri arasında müşterek kullanılan ve tartışılan bu terimin tefsir ilmi açısından da ele alınmasını amaçlayan çalışmamız, bu yönüyle özgün bir nitelik taşımaktadır. Haber-i vâhidin çoğunlukla delil değeri üzerinden tartışılması, bilhassa fıkıh alanında yapılan çalışmaları, mezheplerin bu konudaki görüş ve tutumlarını tespit etmeye yönlendirmiştir. Buradan hareketle çalışmada, mezhep kimliğiyle ön plana çıkmış farklı mezheplere mensup müfessirler özelinde haber-i vâhid yaklaşımının ele alınması hedeflenmektedir. Her müfessirin mensup olduğu mezhebin yaklaşımını esas alarak Kur’ân’ı yorumlamasının sebep olduğu, haber-i vâhid örneğinde Kur’ân yorumunun ideal bir tefsir tarzı olup olmadığı probleminin değerlendirilme gayreti, çalışmanın önemine katkı sağlamaktadır.
Originality of chronotope palette of Amelie Nothomb works
Authors: Cherkashyna Tetiana , Bieliavska Mariia , Satanovska Hanna , Pesotska Diana , Kushchenk Zhanna
Published: May 2023

The article is dedicated to studying the chronotypical models and their impact upon poetical features of novels by French-speaking female writer Amelie Nothomb. Such novels by Nothomb as “Hygiene and the Assassin”, “The Stranger Next Door”, “Attempt”, “Fear and Trembling”, “The Character of Rain” and “Cosmetics of the Enemy”. Attention is paid to inter-genre and enter-gender synthesis of Nothomb novels which significantly influences the specifics of building up the chronotypical models of the novels being analyzed. Studying peculiarity of genre form of A.Nothomb novels revealed polygenre synthesis which is inherent for them which is based upon diffusion of epic and dramatic kinds of great and small epic genres. Distinctive feature of novel works by this female writer is determined by complex stratification of chronotype layers, comprising chronotype models of enclosed spaces, idyll chronotype, chronotype of raving, chronotype of art, chronotype of childhood, chronotype of love. Analysis of time-space models testifies about inclination of the writer to realistic, recognizable space with involvement of effective toponyms from historic and social-cultural contexts as different from time and space ambiguity which is inherent for postmodern text. Enclosed spaces are typical for Nothomb novels (building, house, room). Time in the novels has distinctive features of biographic, calendar, day time and historic time. Events take place in logical time sequence, creating linear process, ascending gradation of events is frequent to enhance psychological tension.
El gestor empresarial y las complicaciones contemporáneas de su misión: Retos y perspectivas
Authors: Abad Pablo
Published: May 2023

Esta investigación tiene como objetivo identificar las complicaciones contemporáneas afrontadas por los gestores empresariales en el desarrollo de sus funciones. Mediante la revisión de la literatura, se analizan factores externos, como la innovación y la globalización, que pueden ser amenazantes pero cuya relevancia se ve opacada por la pandemia de la COVID-19. Los hallazgos principales muestran que, en conjunto con complicaciones históricas, la pandemia ha enfrentado a la gestión empresarial con retos consistentes, incidiendo así en la perspectiva de su misión contemporánea.
'Thank you for telling our story’: An exploration of the needs of migrant nurses undergoing competence assessment
Authors:   , Harvey Geoffrey
Published: May 2023

The New Zealand health care system is heavily dependent on the inflow of internationally qualified nurses. It is becoming increasingly important to understand this group, to be able to attract, retain and develop this essential component of the health care system. While interest has been shown by the research community towards these nurses, this enquiry sought to give them a voice, to let them express what they felt their needs were and therefore to empower them as a previously undervalued and unheard group in nursing in New Zealand; it sought to tell their story. The aim of this research enquiry was to understand the needs of nurses migrating to New Zealand – providing an opportunity for international nurses to provide their voice and perspective on what they need from new colleagues and therefore become empowered to succeed. A case study methodology was used, following the emancipatory and constructivist paradigms. The case in the present work-based enquiry was the international nurse who entered the competence assessment process and nurse workforce. Two groups were investigated: newly arrived candidates for NZ nurse registration and international NZ registered nurses who were already working here. Data was collected using a survey questionnaire and semi-structured interviews. The investigation revealed that international nurses had their own perspective on what they needed in order to be successful. Suggestions were gained around Competence Assessment Programme content. Responses were compared to the Maslow hierarchy of needs framework and a new model called the Prism Model of Migrant Nurse Needs was created. This study has revealed new and significant information about how migrant nurses can be supported to succeed, both during their initial process of assessment and when they join the nurse workforce. The health care system in New Zealand is heavily dependent on international nurses. By better understanding their needs, international nurses can be more effectively supported to succeed during their professional assessment and employment in the healthcare sector.
INTELLECTUAL CAPITAL TERHADAP CAPITAL GAIN MELALUI CORPORATE PERFORMANCE
Authors: Arifin Andi Harmoko
Published: May 2023

This research aims to find out and analyze the effect of Intellectual capital on capital gains through corporate performance. The characteristics of the sample data include data on the financial statements of 10 companies belonging to the automotive company group with a financial reporting period of 6 years. From this data, indicators are calculated using a ratio formula based on variable measurement indicators with statistical application programs, including SPSS version 21 (Statistical Program for Social Science) and AMOS (Analysis Moment of Structure) version 20, which are packages in the SEM (Structural Equation Model) program. ). The results of this study indicate that intellectual capital, which consists of value added capital employed, value added Human capital , and structural capital value has a positive and significant effect on corporate performance. Intellectual capital consists of value added capital employed, value added Human capital , and structural capital value through corporate performance has a positive and significant effect on capital gains. Intellectual capital consisting of value added capital employed, value added Human capital , and structural capital value has a positive and significant impact on capital gains. It indicates that increasing the intellectual capital budget will immediately increase the company's capital gains. Corporate performance has a positive and significant influence on capital gains. It suggests that the level of corporate performance will be followed by the rise and fall of the company's capital gains.

Key words: Intellectual Capital, Capital Gain, Corporate Performance
Future of Carbon Storage in the Yangtze River Basin, China under Alternative Climate and Land-Use Pathways
Authors: Zhang Qi , Zhang Guanshi , Zhang Xiu , Liu Dongsheng , Fang Ruying , Dong Na , Wu Hongjuan , Li Sen
Published: May 2023

While the Chinese government has put a strong emphasis on combating climate change and pledged to strive for “carbon neutrality” in the 2060s, it is fundamental to assess the likely evolution of carbon storage in China’s terrestrial ecosystems. Here, we conducted a simulation study grounded by recent empirical evidence and advances in modeling techniques to project the spatiotemporal dynamics of carbon storage of the Yangtze River Basin (YRB)’s ecosystem from 2015 to 2050. Two sets of scenarios were developed to analyze the plausible effects of land-use change, climatic change, and carbon policy on carbon dynamics. The results show that the estimated total carbon storage of the YRB’s ecosystem was 21.75 Pg C in 2015, accounting for about a quarter of the total in China. Model simulations projected an overall increase in carbon storage of the YRB’s ecosystem. Under the combined scenarios, land-use change and climate change contributed to total carbon sequestration by 1.45 to 2.02 PgC and 1.64 to 2.00 PgC, respectively. Under the carbon tax scenario, due to an increase in the extent of forest driven by different carbon regimes, the YRB was projected to absorb 1.26 to 2.32 PgC by 2050. Several regions had been projected under threats of severe carbon losses, including a few places with high present-day carbon density in the middle reaches of the YRB. Our results could provide a more complete picture of carbon sequestration potential of the YRB’s ecosystems, which could benefit the formulation of nature-based solutions.
Business Modeling Innovation Using Artificial Intelligence Technology
Authors: Riya Widayanti  , Lista Meria
Published: May 2023

Startups embracing artificial intelligence (AI) as a component of their business models are quickly emerging right now. The application of AI technology in business has been going on for a while, even though recent research reveals that new or alternative business models are being implemented.It might be claimed that AI technology has been used to business models for a very long time, which puts into question the uniqueness of these business models. In order to better understand how AI companies' business models may differ from traditional IT business models, this study compares them to each other. The first step is to create a taxonomy of business models for AI businesses using a sample of 162 Worldwide Stratup, from which four archetypal business models are derived: Deep technology researcher, data analytics supplier, AI product and service provider, and facilitator of AI development The following are three main elements of startup business models for AI firms that are discussed based on this descriptive analysis: (1) new value propositions made possible by AI, (2) Various uses of data to create value and (3) How AI technology affects general business reasoning. By defining their key purposes, common instantiations, and distinguishing features, this research adds to our fundamental understanding of the AI start-up business model. This study suggests intriguing directions for further investigation in the field of entrepreneurship. À It is structured to foster entrepreneurial activity. Taxonomies and models are actually instrument.
Implementation of White Hat SEO-Based Digital Incubator Platform
Authors: Ihya Syihabul Fadli  , Nuke Puju Lestari  , Ananda Alifia Putri
Published: May 2023

Advances in information technology are developing rapidly in various areas of life. The Internet is one of the most influential information and communication technologies. A website, one of the Internet technologies, is not only a medium of information, but also a process that supports a company's business. No effect. SEO (Search Engine Optimization) is one of the advertising methods using search engine optimization so that the website created by our  company will be displayed on the top of the search engine page or on the first page (first page). This research was initially conducted on the Business Incubator website, which did not follow his SEO techniques. Then some steps were also taken by implementing on-page SEO  techniques such as title tag, content, meta keywords, keyword optimization for meta description and sharing on social media. This point. A test as a benchmark for successful implementation of SEO techniques. As a result of implementing SEO techniques, his website's SERP (Search Engine Results Pages) on search engines increased and in the second month he successfully landed on Google's second page and was indexed by Google Search. The first page was not successful in March.
Education on the Use of Iot Technology for Energy Audit and Management Within the Context of Conservation and Efficiency
Authors: Wahyu Sejati  , Vivi Melinda
Published: May 2023

Education on the use of IoT technology for energy audit and management within the context of conservation and efficiency The demand for electrical energy rises in direct proportion to a region's economy. The basic electricity rate rises in response to the steadily growing demand for electrical energy. Increased use of electrical energy is a result of wasteful conduct and a disregard for equipment standardization.  increases the utilization of electrical energy. The local population still does not appear to be concerned or aware of how crucial it is to keep the electrical supply sustainable.Many studies that are pertinent to energy efficiency and conservation education have been conducted.Thus, the community needs to be informed of this information in order to, among other things, increase understanding, encourage the community to behave economically, conduct audits, and manage electrical energy in accordance with standardized practices. SMK N 1 Brebes, a vocational school for electrical and electronics, is a setting that is pertinent to the use of this technology. The development in students' abilities after engaging in this activity shows that it has delivered education in the form of reading material and energy management practice.
Implementation of Information and Communication Technology in Management Learning System During the Covid 19 Pandemic
Authors: Putri Fadia Sasabila , Dermawanis Zega
Published: May 2023

This study examines the use of information technology in the management system of Indonesian higher education institutions. This could have been more optimal and evenly distributed in terms of hardware and management. This study is an international journal study. Input resource findings include visualizers/document cameras, computers, whiteboards, student-ready systems, and application programs. Output resources include projectors, interactive whiteboards, and displays. monitor, television, etc. Finally, other ICT devices include digital cameras, switchers, digital recorders, and other innovations. In short, inequalities in the infrastructure supporting the application of this technology in education and the need for better preparedness of human resources for the use of information and communication technologies in learning.
Conformational approach to the crystallization mechanisms of organosilicon liquids of PMS brand in a non-uniform temperature field
Authors: Matveev N. N. , Lisitsyn V. I. , Kamalova N. S. , Evsikova N. Yu. , Vnukova S. V.
Published: May 2023

The possibility of using the conformational approach to describe the crystallization kinetics during melt-crystal phase transitions in an inhomogeneous temperature field and to determine the molar mass range corresponding to a change in the crystallization mechanism is shown using the example of PMS brand organosilicon liquids. It is established that the curve of dependence of the mean square of the dipole moment of a macromolecule on the average molar mass of an organosilicon polymer contains three sections, each of which has its own crystallization mechanism.
A QUALITATIVE STUDY ON THE IMPROVEMENT OF DISEASE MANAGEMENT POLICIES IN DIABETES IN TURKEY
Authors: Mutlu Hatice , Sur Haydar
Published: May 2023

This study, it was aimed to determine the need for disease management in diabetes in Turkey and to reveal the recommendations for diabetes disease management policies as part of the identified needs. In this study, the research design was planned as a case study and, the snowball sampling method was used as part of the scope of qualitative research. A total of 21 individuals, 6 doctors, 3 diabetic nurses, 6 academics, and 6 adult diabetics were actualized using semi-structured forms with a thorough interview technique. The data collected were evaluated with descriptive analysis and content analysis methods. In the analysis of the data, the “Nvivo 12. Program” was used. The findings were discussed based on the relevant literature, and conclusions and recommendations were reached in line with the research purposes. The participants stated that the practices related to disease management in diabetes have improved compared to the past, but that the development process should continue. The participants stated that there is a need for a multidisciplinary systematic process structuring that will prioritize the patient and their needs and that will help patients to live their lives healthy and free from complications. In terms of the burden of disease, diabetes is a significant issue that affects both Turkey and the rest of the world. We propose that the health policy, health service delivery, health system structure, and multidisciplinary work related to the disease management approach in diabetes in Turkey should be determined and steps should be taken to improve it.
Implementasi Pendidikan Karakter di Sekolah Katolik dalam Terang Dokumen Educating to Fraternal Humanism
Authors: Dasrimin Henderikus
Published: May 2023

The teaching of biblical inspiration is one of the basic understandings of the Bible in the Catholic Church. Reading and using the Bible does not guarantee the correct understanding of biblical inspiration. Therefore, this article intends to examine the understanding of biblical inspiration by the Christians and the church's teaching in the documents Dei Verbum and The Inspiration and Truth of Sacred Scriptures. This study uses qualitative method with a field study and literature study. Through this study, an understanding was obtained that the Christians have not understood the teaching of biblical inspiration correctly based on the church’s teaching, where inspiration signifies the cooperation between God and humans in writing the Scriptures. Thus the church needs to make a pastoral service to explain the church's teaching about biblical inspiration correctly.
Sigillum Sacramentale: Rahasia Sakramental Pengakuan Dosa. Studi Kanonik
Authors: Galed Daniel Ortega
Published: May 2023

One of the special graces possessed by a priest is the authority to act in persona Christi capitis when granting absolution for the sins of the penitent. They received this authority from Christ himself, the only One who could forgive human sins. However, that grace also brings a great duty. They are bound by a divine obligation to keep the seal of confession. This canonical study will describe how the concept of the sigillum sacramentale or the inviolable sacramental seal of confession is developed in canon law. It will also explain what is meant by divulging the seal of confession directly and indirectly. From the perspective of the Penal Code of Canon law, it will also discuss canonical sanctions for priests who violate them and how the punishments will be revoked. Finally, this study is expected to foster seriousness and responsibility for priests in serving the Sacrament of Penance, the sacrament that reconciles humans with God.
Pelatihan dan Pendampingan E-Learning Readiness pada Transformasi Pembelajaran Daring-Luring Berbasis PBL Untuk Guru SMP dan MTS
Authors: Winarsih Dwi , Ramadhika Boris , Singgih Suwito
Published: May 2023

Transformasi pembelajaran dari daring ke luring menimbulkan berbagai masalah, salah satunya adalah kesiapan guru. Program Pengabdian Kepada Masyarakat ini bertujuan untuk mempersiapkan kompetensi guru pada transformasi pembelajaran daring-luring dengan berbasis pada Problem Based Learning (PBL). Metode yang digunakan dalam kegiatan ini adalah observasi, pelaksanaan, dan evaluasi. Kegiatan ini dilaksanakan di dua mitra, yaitu MTs Maâ€™arif dan SMP Alqodiriyah yang berada di desa Windusari, Magelang, Jawa Tengah yang berlangsung dari bulan Juni-September 2022. Hasil dari kegiatan ini berupa kegiatan dalam rangka memfasilitasi kesiapan guru akan perubahan pembelajaran ke luring, dengan tidak menghilangkan apa yang sudah dipelajari terkait dengan pembelajaran daring, yaitu E-learning readiness. Pengaplikasian teknologi dengan memanfaatkan aplikasi seperti Quizziz, Google Classroom, dan Filmorago menjadi solusi dari masalah yang ada di kedua mitra tersebut. Pelatihan dan pendampingan yang dilakukan terbukti mampu memberikan peningkatan terhadap guru dalam menghadapi transformasi pembelajaran daring-luring. Kedepannya, guru diharapkan mampu secara mandiri mengembangkan materi-materi lain guna menunjang pembelajaran yang lebih maju. Kata Kunci: E-learning readiness, PBL, Pelatihan, Pendampingan
Pelaksanaan Focus Group Discussion Sebagai Upaya Penguatan Reputasi Nanas Bikang Sebagai Indikasi Geografis
Authors: Darwance Darwance , Sari Rafiqa , Asits Aruna
Published: May 2023

Sebagai daerah bercorak kepulauan, Kepulauan Bangka Belitung memiliki banyak sumber daya alam yang di antaranya berpotensi didaftarkan sebagai indikasi geografis, salah satunya adalah Nanas Bikang yang ada di Desa Bikang, Kecamatan Toboali, Kabupaten Bangka Selatan. Hanya saja, Nanas Bikang belum terdaftar sebagai indikasi geografis sampai saat ini. Nanas Bikang baru terdaftar sebagai varietas lokal, bukan indikasi geografis. Nanas Bikang terdaftar dengan Tanda Daftar Varietas Tanaman Nomor: 1557/PVL/2020 yang dikeluarkan oleh Pusat Perlindungan Varietas Tanaman dan Perizinan Pertanian Kementerian Pertanian Republik Indonesia tanggal 26 Oktober 2020. Oleh sebab itu, melalui kegiatan pengabdian kepada masyarakat, dilaksanakan Focus Group Discussion (FGD) sebagai upaya penguatan reputasi Nanas Bikang sebagai indikasi geografis. Dari kegiatan yang dilaksanakan, diketahui bahwa pada dasarnya Nanas Bikang memiliki karakter khas yang berpotensi diidaftarkan sebagai indikasi geografis. Oleh sebab itu, sejumlah langkah konkrit harus dilakukan, termasuk menjaga reputasi yang ada sekarang.
Workshop Pengolahan Mie Kopi
Authors: Murti Paulus Damar Bayu , Kuspradanarto Raka Bachtiar , Mahardika Anggara , Hapsari Martina Widhi , Anggraeni Novia , Rizkaprilisa Windy
Published: May 2023

Mie merupakan jenis pangan yang dapat digunakan sebagai pengganti karbohidrat dari nasi. Biasanya mie ini tergolong sebagai makanan instan karena tidak memerlukan proses memasak yang begitu lama. Pandemi mengajarkan untuk tetap di rumah saja, dan kita dituntut untuk terus kreatif dan inovatif walau di rumah saja. Kegiatan pengabdian masyarakat ini bertujuan untuk memberikan pelatihan pengolahan mie kopi kepada masyarakat khususnya kepada Ibu-Ibu PKK tingkat Kota Semarang, Provinsi Jawa Tengah. Metode yang digunakan dalam kegiatan pengabdian kepada masyarakat ini adalah metode pelatihan demo memasak dilakukan secara daring menggunakan platform zoom meeting. Kegiatan berlangsung dimulai dengan tahapan persiapan, pelaksanaan, tanya jawab, dan pelaporan. Sebanyak kurang lebih 40 orang jumlahnya yang mengikuti kegiatan pelatihan mie kopi ini. Materi yang disampaikan dalam kegiatan workshop mie kopi ini adalah pembuatan mie dari bahan dasar tepung, penggilingan, pembentukan mie, dan proses memasak mie kopi menjadi sebuah hidangan. Kegiatan ini mendapatkan respon positif dari para peserta online yang hadir dengan berbagai pertanyaan disampaikan saat workshop berlangsung. Setelah kegiatan dilaksanakan, diharapkan peserta memperoleh ide inovasi pangan baru dalam bentuk mie kopi.