Tendency Of Incidence With Nonspecific Ulcerative Colitis In Kazakhstan
Authors:   Astana Medical University, Nur-Sultan, Republic of Kazakhstan, Kenzhebekova Shyryn ,   Central Asian Cancer Institute, Nur-Sultan, Republic of Kazakhstan, Sakhanov Sauirbay ,   Astana Medical University, Nur-Sultan, Republic of Kazakhstan; Central Asian Cancer Institute, Nur-Sultan, Republic of Kazakhstan, Turebaev Dulat ,   Astana Medical University, Nur-Sultan, Republic of Kazakhstan, Nurtazinova Gauhar ,   Astana Medical University, Nur-Sultan, Republic of Kazakhstan, Urazova Saltanat ,   Astana Medical University, Nur-Sultan, Republic of Kazakhstan, Kulmirzaeva Dariyana ,   National Center of Neurosurgery, Nur-Sultan, Republic of Kazakhstan; Central Asian Cancer Institute, Nur-Sultan, Republic of Kazakhstan, Amanshayeva Akmaral ,   Central Asian Cancer Institute, Nur-Sultan, Republic of Kazakhstan, Bilyalova Zarina ,   Central Asian Cancer Institute, Nur-Sultan, Republic of Kazakhstan, Izimbergenov Mirsaid ,   Astana Medical University, Nur-Sultan, Republic of Kazakhstan, Kozhakhmetov Saken ,   Astana Medical University, Nur-Sultan, Republic of Kazakhstan; Central Asian Cancer Institute, Nur-Sultan, Republic of Kazakhstan, Igissinov Nurbek ,   Astana Medical University, Nur-Sultan, Republic of Kazakhstan; Central Asian Cancer Institute, Nur-Sultan, Republic of Kazakhstan; Eurasian Institute for Cancer Research, Bishkek, Kyrgyz Republic
Published: June 2021

Nonspecific ulcerative colitis is a chronic inflammatory bowel disease of an immune nature with frequent localization in the large intestine. A pattern is noted that in the northern and western continents they suffer more often than in Asia. To identify risk factors in a population, epidemiological studies must firstly assess the incidence of disease. Aim. To study the trends of nonspecific ulcerative colitis (NUC) incidence in Kazakhstan. Material and methods. The research material was compiled summary reporting form number 12 of the Ministries and the Health of the Republic of Kazakhstan on new cases of nonspecific ulcerative colitis (ICD-10 – K51), established for the first time. A retrospective study was used as the main method for studying the incidence of NUC. According to generally accepted methods of biomedical statistics, extensive, intensive and equalized indicators of the incidence of NUC were calculated. Results and discussion. For 2013-2018 14,079 new cases of NUC were registered in the republic, of which 15 were in children – 15.3%, teenagers – 4.8% and adults – 79.8%. The average annual incidence rate of NUC in the entire population of Kazakhstan was 13.5±2.10/0000 (95% CI=9.4-17.50/0000), and for population groups having been studied was: in children – 7.2±2.10/0000 (95%CI=3.8-12.00/0000), among teenagers – 18.7±5.00/0000 (95% CI=9.0-28.50/0000) and the adult population 15.4±1.90/0000 (95% CI=11.8-19.10/0000). The difference in morbidity between groups was statistically significant. Disease tended to decrease in all age groups: in the adult population (Т=−12.3%), children (Т=−43.7%) and in adolescents (T=-50.1%). Conclusion. According to the dynamics, NUC incidence in Kazakhstan has a decreased tendency due to the child and adolescent population. The results obtained are recommended to be taken into account by health authorities when making managerial decisions. Keywords: nonspecific ulcerative colitis, morbidity, trends, Kazakhstan.