bluuebunny/crossref_metadata_2025 huggingface dataset:
Genomic Characterization of a Relative of Mumps Virus in Lesser Dawn Bats of Southeast Asia
Authors: Paskey Adrian C. , Lim Xiao Fang , Ng Justin H. J. , Rice Gregory K. , Chia Wan Ni , Philipson Casandra W. , Foo Randy , Cer Regina Z. , Long Kyle A. , Lueder Matthew R. , Glang Lindsay , Frey Kenneth G. , Hamilton Theron , Mendenhall Ian H. , Smith Gavin J. , Anderson Danielle E. , Wang Lin-Fa , Bishop-Lilly Kimberly A.
Published: March 2023

The importance of genomic surveillance on emerging diseases continues to be highlighted with the ongoing SARS-CoV-2 pandemic. Here, we present an analysis of a new bat-borne mumps virus (MuV) in a captive colony of lesser dawn bats (Eonycteris spelaea). This report describes an investigation of MuV-specific data originally collected as part of a longitudinal virome study of apparently healthy, captive lesser dawn bats in Southeast Asia (BioProject ID PRJNA561193) which was the first report of a MuV-like virus, named dawn bat paramyxovirus (DbPV), in bats outside of Africa. More in-depth analysis of these original RNA sequences in the current report reveals that the new DbPV genome shares only 86% amino acid identity with the RNA-dependent RNA polymerase of its closest relative, the African bat-borne mumps virus (AbMuV). While there is no obvious immediate cause for concern, it is important to continue investigating and monitoring bat-borne MuVs to determine the risk of human infection.
Growth Velocity and Nutritional Status in Children Exposed to Zika Virus during Pregnancy from Amazonas Cohort, Brazil
Authors: Peixoto Lucíola de Fátima Albuquerque de Almeida , Abtibol-Bernardino Marília Rosa , Guerra Cecilia Victoria Caraballo , de Oliveira Geruza Alfaia , Chaves Beatriz Caroline Soares , de Souza Rodrigues Cristina , de Andrade Anny Beatriz Costa Antony , de Fátima Redivo Elijane , Fernandes Salete Sara Alvarez , Otani Rodrigo Haruo , da Silva Neto Alexandre Vilhena , da Silva Balieiro Antônio Alcirley , Cabral Celso Rômulo Barbosa , Baia-da-Silva Djane , Castilho Márcia da Costa , Bôtto-Menezes Camila Helena , Alecrim Maria das Graças Costa , Leal Maria do Carmo , Benzecry Silvana Gomes , Martinez-Espinosa Flor Ernestina
Published: March 2023

The high incidence of Zika virus (ZIKV) infection in the period of 2015–2016 in Brazil may have affected linear height growth velocity (GV) in children exposed in utero to ZIKV. This study describes the growth velocity and nutritional status based on the World Organization (WHO) standards of children exposed to ZIKV during pregnancy and followed up in a tertiary unit, a reference for tropical and infectious diseases in the Amazon. Seventy-one children born between March 2016 and June 2018 were monitored for anthropometric indices: z-score for body mass index (BMI/A); weight (W/A); height (H/A) and head circumference (HC/A); and growth velocity. The mean age at the last assessment was 21.1 months (SD ± 8.93). Four children had congenital microcephaly and severe neurological impairment. The other 67 were non-microcephalic children (60 normocephalic and 7 macrocephalic); of these; 24.2% (16 children) had neurological alterations, and 28.8% (19 children) had altered neuropsychomotor development. Seventeen (24.2%) children had inadequate GV (low growth velocity). The frequencies of low growth among microcephalic and non-microcephalic patients are 25% (1 of 4 children) and 23.9% (16 of 67 children); respectively. Most children had normal BMI/A values during follow-up. Microcephalic patients showed low H/A and HC/A throughout the follow-up, with a significant reduction in the HC/A z-score. Non-microcephalic individuals are within the regular ranges for H/A; HC/A; and W/A, except for the H/A score for boys. This study showed low growth velocity in children with and without microcephaly, highlighting the need for continuous evaluation of all children born to mothers exposed to ZIKV during pregnancy.
Heparan Sulfate and Enoxaparin Interact at the Interface of the Spike Protein of HCoV-229E but Not with HCoV-OC43
Authors: Fuochi Virginia , Floresta Giuseppe , Emma Rosalia , Patamia Vincenzo , Caruso Massimo , Zagni Chiara , Ronchi Federica , Ronchi Celestino , Drago Filippo , Rescifina Antonio , Furneri Pio Maria
Published: March 2023

It is known that the spike protein of human coronaviruses can bind to a secondary receptor, or coreceptor, to facilitate the virus entry. While HCoV-229E uses human aminopeptidase N (hAPN) as a receptor, HCoV-OC43 binds to 9-O-acetyl-sialic acid (9-O-Ac-Sia), which is linked in a terminal way to the oligosaccharides that decorate glycoproteins and gangliosides on the surface of the host cell. Thus, evaluating the possible inhibitory activity of heparan sulfate, a linear polysaccharide found in animal tissues, and enoxaparin sodium on these viral strains can be considered attractive. Therefore, our study also aims to evaluate these molecules’ antiviral activity as possible adsorption inhibitors against non-SARS-CoV. Once the molecules’ activity was verified in in vitro experiments, the binding was studied by molecular docking and molecular dynamic simulations confirming the interactions at the interface of the spike proteins.
Burden of Influenza and Respiratory Syncytial Viruses in Suspected COVID-19 Patients: A Cross-Sectional and Meta-Analysis Study
Authors: Costa Vivaldo Gomes da , Gomes Ana Júlia Chaves , Bittar Cíntia , Geraldini Dayla Bott , Previdelli da Conceição Pâmela Jóyce , Cabral Ágata Silva , Carvalho Tamara , Biselli Joice Matos , Provazzi Paola Jocelan Scarin , Campos Guilherme Rodrigues Fernandes , Sanches Paulo Ricardo da Silva , Costa Paulo Inácio , Nogueira Maurício Lacerda , Araujo João Pessoa , Spilki Fernando Rosado , Calmon Marília Freitas , Rahal Paula
Published: March 2023

Non-SARS-CoV-2 respiratory viral infections, such as influenza virus (FluV) and human respiratory syncytial virus (RSV), have contributed considerably to the burden of infectious diseases in the non-COVID-19 era. While the rates of co-infection in SARS-CoV-2-positive group (SCPG) patients have been determined, the burden of other respiratory viruses in the SARS-CoV-2-negative group (SCNG) remains unclear. Here, we conducted a cross-sectional study (São José do Rio Preto county, Brazil), and we collected our data using a meta-analysis to evaluate the pooled prevalence of FluV and RSV among SCNG patients. Out of the 901 patients suspected of COVID-19, our molecular results showed positivity of FluV and RSV in the SCNG was 2% (15/733) and 0.27% (2/733), respectively. Co-infection with SARS-CoV-2 and FluV, or RSV, was identified in 1.7% of the patients (3/168). Following our meta-analysis, 28 studies were selected (n = 114,318 suspected COVID-19 patients), with a pooled prevalence of 4% (95% CI: 3–6) for FluV and 2% (95% CI: 1–3) for RSV among SCNG patients were observed. Interestingly, FluV positivity in the SCNG was four times higher (OR = 4, 95% CI: 3.6–5.4, p < 0.01) than in the SCPG. Similarly, RSV positivity was significantly associated with SCNG patients (OR = 2.9, 95% CI: 2–4, p < 0.01). For subgroup analysis, cold-like symptoms, including fever, cough, sore throat, headache, myalgia, diarrhea, and nausea/vomiting, were positively associated (p < 0.05) with the SCPG. In conclusion, these results show that the pooled prevalence of FluV and RSV were significantly higher in the SCNG than in the SCPG during the early phase of the COVID-19 pandemic.
Associations between Health Literacy, Trust, and COVID-19 Vaccine Hesitancy: The Case of Hong Kong
Authors: Tian Cindy Yue , Mo Phoenix Kit-Han , Dong Dong , Qiu Hong , Cheung Annie Wai-Ling , Wong Eliza Lai-Yi
Published: March 2023

This study investigates how health literacy (HL) and trust in health information affected COVID-19 vaccine hesitancy among Chinese Hong Kong adults. A cross-sectional study was conducted in August 2022. A total of 401 participants completed the study. Participants completed a newly developed Hong Kong HL scale and self-reported their trust levels in health information from different resources. The proportions of early uptake of the first dose and booster dose of COVID-19 vaccine were 69.1% and 71.8%, respectively. The risk of delaying the first dose was higher among participants with inadequate functional HL (OR = 0.58, p = 0.015), adequate levels of two subdomains of critical HL (OR = 1.82, p = 0.013; OR = 1.91, p < 0.01), and low-level trust in health information from the government (OR = 0.57, p = 0.019). Respondents with adequate interactive HL (OR = 0.52, p = 0.014) and inadequate level of one subdomain of critical HL (OR =1.71, p = 0.039) were more likely to delay the booster dose. This negative association between critical HL and vaccination was suppressed by trust in health information from the government. This study shows that HL and trust in health information from the government are associated with COVID-19 vaccine hesitancy. Efforts should be directed at providing tailored communication strategies with regard to people’s HL and increasing public confidence in health authorities to decrease vaccine hesitancy.
A Systematic Review of Factors That Influence Parents’ Views and Practices around Routine Childhood Vaccination in Africa: A Qualitative Evidence Synthesis
Authors: Mavundza Edison J. , Cooper Sara , Wiysonge Charles S.
Published: March 2023

A Cochrane review which explored the factors that influence caregivers’ views and practices around routine childhood vaccines worldwide was conducted by Cooper and colleagues. After sampling 154 studies that met their inclusion criteria, the authors included 27 studies in their synthesis, of which 6 were from Africa. The aim of the current review was to synthesise all 27 studies conducted in Africa. We wanted to determine if the inclusion of additional African studies will change any of the themes, concepts or theory generated in the Cochrane review. Our review found that parents’ views and practices regarding childhood vaccination in Africa were influenced by various factors, which we categorised into five themes, namely, ideas and practices surrounding health and illness (Theme 1); social communities and networks (Theme 2); political events, relations, and processes (Theme 3); lack of information or knowledge (Theme 4); and access-supply-demand interactions (Theme 5). All of the themes identified in our review were also identified in the Cochrane review except for one theme, which was lack of information or knowledge. This finding will help to promote vaccine acceptance and uptake in Africa by developing and implementing interventions tailored to address lack of knowledge and information around vaccines.
Comparison of Immunogenicity and Reactogenicity of Five Primary Series of COVID-19 Vaccine Regimens against Circulating SARS-CoV-2 Variants of Concern among Healthy Thai Populations
Authors: Sudjaritruk Tavitiya , Mueangmo Oramai , Saheng Jutamad , Winichakoon Poramed , Salee Parichat , Wongjak Worawan , Chaito Tanachot , Praparattanapan Jutarat , Nuket Khanuengnit , Solai Nuttarika , Wipasa Jiraprapa , Chawansuntati Kriangkrai , Chaiwarith Romanee
Published: March 2023

To compare immunogenicity and reactogenicity of five COVID-19 vaccine regimens against wild-type SARS-CoV-2 and variants of concern (VoCs) among Thai populations, a prospective cohort study was conducted among healthy participants aged ≥18 years who had never been infected with COVID-19 and were scheduled to get one of the five primary series of COVID-19 vaccine regimens, including CoronaVac/CoronaVac, AZD1222/AZD1222, CoronaVac/AZD1222, AZD1222/BNT162b2, and BNT162b2/BNT162b2. Anti-receptor binding domain (anti-RBD-WT) IgG and neutralizing antibody (NAb-WT) against wild-type SARS-CoV-2 were measured at pre-prime, post-prime, and post-boost visits. NAb against VoCs (NAb-Alpha, NAb-Beta, NAb-Delta, and NAb-Omicron) were assessed at the post-boost visit. Adverse events (AEs) following vaccination were recorded. A total of 901 participants (CoronaVac/CoronaVac: 332, AZD1222/AZD1222: 221, CoronaVac/AZD1222: 110, AZD1222/BNT162b2: 128, and BNT162b2/BNT162b2: 110) were enrolled. Anti-RBD-WT IgG and NAb-WT levels increased substantially after each vaccine dose. At the post-boost visit, BNT162b2/BNT162b2 induced the highest GMC of anti-RBD-WT IgG level (1698 BAU/mL), whereas AZD1222/BNT162b2 induced the highest median NAb-WT level (99% inhibition). NAb levels against VoCs, particularly the Omicron strain, were markedly attenuated for all vaccine regimens (p < 0.001). Overall, no serious AEs following vaccination were observed. All five primary series of COVID-19 vaccine regimens were well-tolerated and elicited robust antibody responses against wild-type SARS-CoV-2 but had attenuated responses against VoCs, particularly the Omicron strain, among healthy Thai populations.
A Voice-Annotated Digital Decision Aid to Promote Child Influenza Vaccination: A Feasibility Study
Authors: Gun Shih Ying , Moosa Aminath Shiwaza , Poh Chen Wei , Ng Sherryl Lei , Tan Ngiap Chuan
Published: March 2023

(1) Background: Child influenza vaccine uptake is suboptimal due partly to vaccine hesitancy. A voice-annotated digital decision aid, Flu Learning Object (FLO), was developed to facilitate parental decision-making. This study assessed parental views on FLO’s usability and utility and determined its preliminary effectiveness in increasing vaccine intention and uptake; (2) Methods: A single-center mixed method study was conducted in a public primary care clinic in Singapore. Parents of children aged 6 months to 5 years who were unvaccinated in the preceding year were recruited. In-depth interviews explored their views of using FLO. Pre- and post-FLO questionnaires assessed their vaccine intention and perceived usability using the System Usability Scale (SUS); (3) Results: 18 parents were recruited. They became more aware of benefits and potential complications, distinguished influenza from the common cold, and recognized recommendations by National Childhood Immunisation Schedule. FLO addressed parents’ concerns and supported their decision-making process. FLO has good usability with a mean SUS score of 79.3, ranked at approximately the 85th percentile. The usage of FLO significantly increased vaccine intention from 55.6% to 94.4% (p = 0.016) with an actual vaccine uptake rate of 50%; (4) Conclusions: Parents generally accepted FLO, which positively influenced their intention to vaccinate their child against influenza.
Gallocatechin Gallate Inhibits the Replication of Pseudorabies Virus via Suppressing the Entry and Release Stages in Its Replication Cycle
Authors: Bo Zongyi , Zhu Jinjin , Guo Mengjiao , Zhang Chengcheng , Cao Yongzhong , Zhang Xiaorong , Wu Yantao
Published: March 2023

The pseudorabies virus is a widespread swine pathogen that has caused significant economic losses to the global pig industry. Due to the emergence of PRV variant strains in recent years, vaccines cannot provide complete protection against the infection of PRV. Therefore, the research on antiviral compounds is of great importance for PRV treatment. In this study, an EGFP-labeled PRV was used to screen anti-PRV compounds from 86 natural product extracts. Gallocatechin gallate was found to efficiently inhibit the replication of PRV with a half-maximal inhibitory concentration (IC50) of 0.41 μM. In addition, it was found that gallocatechin gallate was unable to directly inactivate PRV and had no effect on the attachment stage of PRV. However, it was found that gallocatechin gallate significantly suppressed the viral entry stage. Furthermore, it was found that the release stage of PRV was also significantly suppressed by gallocatechin gallate. Together, this study found that gallocatechin gallate could efficiently inhibit the replication of PRV by suppressing the entry and release stages of PRV, which will contribute to the development of a new therapeutic strategy against PRV infection.
A Review on the Stability, Sustainability, Storage and Rejuvenation of Aerobic Granular Sludge for Wastewater Treatment
Authors: Shameem K. S. , Sabumon P. C.
Published: March 2023

Aerobic granular sludge (AGS) is a recent innovative technology and is considered a forthcoming biological process for sustainable wastewater treatment. AGS is composed of the dense microbial consortium of aerobic, anaerobic, and facultative types of bacteria. The mechanism of AGS formation and its stability for long-term operation is still a subject of current research. On the other hand, AGS makes the treatment process sustainable in a cost-effective way. However, in order for AGS to be applied in a broader range of applications, there are several challenges to overcome, such as slow-speed granulation and the disintegration of AGS after granulation. Many factors play a role in the stability of granules. The storage of granules and the later use of them for granulation startup is a feasible method for reducing the time for granulation and maintaining stability. This review focuses on the granulation process and characteristics of AGS, granulation time and the stability of AGS under different conditions, the comparison of different storage methods of granules, and their recovery and rejuvenation. From this review, it is evident that additional research is required to assess the effectiveness of regenerated AGS after prolonged storage to promote AGS technology for commercial applications.
Impact of Artificial Islands and Reefs on Water Quality in Jinmeng Bay, China
Authors: Fan Jiadong , Kuang Cuiping , Liu Huixin , Wang Dan , Liu Jiantao , Wang Gang , Zou Qingping
Published: March 2023

Recurrent green tide has been widely studied due to its severe damage to coastal ecosystem. Jinmeng Bay, a popular resort in northeastern China, has suffered from green tide events since 2015, after the constructions of artificial islands and submerged reefs. To investigate the potential impacts of artificial islands and reefs on the water quality in Jinmeng Bay, a MIKE 21 numerical model was established by coupling a hydrodynamic model with a transport model of Chemical Oxygen Demand (COD) and nitrate ion (NO3−). The changes in the water quality in Jinmeng Bay by the initial, first-stage and current construction conditions of artificial islands and submerged reefs were simulated. The model results indicated that: (1) The artificial islands and reefs in Jinmeng Bay hinder the tidal currents and weaken the tidal actions. (2) The weakened tidal actions at the estuary lead to the accretion of COD and NO3−. The neap tides generate a littoral zone with the high concentration of COD and NO3−, and the spring tides maintain the zone at the estuary. (3) NO3− is more sensitive than COD to the variation of hydrodynamic conditions. The NO3− concentration in the north of Conch artificial island is altered significantly, where the construction of the artificial structures decrease the concentration by ~30%, while the demolition of the connection road increases the concentration beyond its initial values by 16~21%. (4) Under the current construction conditions, the rising concentrations of COD (up to 2%) and NO3− (up to 40%) increase the frequency and scale of green tides in Jinmeng Bay considerably. Therefore, continuous monitoring of water quality is required for this region.
Organization of remote workers’ labor
Authors:   Department of Banking and Entrepreneurship, State University of Management, Moscow,, Makeeva Viktoriya Gennadievna , Minchenkova Olga Yurievna ,   Department of Theory and Systems of Sectoral Management, Russian Presidential Academy of National Economy and Public Administration, Moscow, Fedorova Natalya Vasilievna ,   Department of Management, Moscow University for the Humanities
Published: March 2023

The article deals with issues related to new forms of employment and the requirements that must be taken into account when using them. New programs and IT technologies that can be applied instead of foreign ones are presented. The materials of the article can be used as part of the training in the areas of "Enterprise Economics" and "Personnel Management".
Role and significance of the State National Dance and Song Theater "Altam" in the cultural space of the Altai Republic
Authors:   Moscow University for the Humanities, Kurdyapov Bayram Vyacheslavovich
Published: March 2023

The article is devoted to the consideration of issues related to the study of the role and significance of the State National Dance and Song Theater "Altam" in the cultural space of the Altai Republic. In the process of the research, special attention is paid to the methods and tools through which the theater attracts spectators and cultural and art workers. Also, specific examples describe the influence of the theater on the familiarization of the Altai population with art, as well as on the preservation and multiplication of cultural heritage.
Current issues of compliance practice in the transition to electronic personnel reporting
Authors:   Department of Psychology and Human Capital Development, Financial University under the Government of the Russian Federation, Buyanova A.V. , Benavides Mal'donado R.K. ,   Faculty of Law of the Higher School of Economics
Published: March 2023

The article discusses the problems associated with the transition to electronic personnel reporting and the possibility of solving them through the introduction of compliance practices in the company.
Conclusion and termination of an employment contract with employees under the age of 14
Authors:   Polytechnic College of Sakhalin State University, Kartashova G.N.
Published: March 2023

The article deals with topical issues of legal regulation of the conclusion and termination of an employment contract with employees under the age of 14. The author draws attention to issues that are not regulated in legislation, but raise questions in practice. The article also raises the question of the relationship between labor and civil law contracts in the regulation of the labor of minors.
To the question of remuneration for shift workers
Authors:   Departments of Environmental, Natural Resource and Labor Law of Udmurt State University, Izhevsk, Russkikh T.V.
Published: March 2023

The salary received by an employee under an employment contract is, as a rule, his only source of livelihood. Within the framework of this article, some problems of remuneration of workers working in shifts are considered. The article concludes that the abuse by employers of the freedom granted to them by the Labor Code of the Russian Federation leads to a significant deterioration in the position of shift workers compared to ordinary workers. At the same time, differentiation norms should not be interpreted arbitrarily in violation of the Constitution of the Russian Federation and fundamental norms of labor law, and should be discriminatory. It is concluded that the freedom of the employer as a party to an employment contract, even within the framework of the institution of remuneration, should be limited within certain limits. The ways of improving the current labor legislation are proposed.
Russian lubricants to replace foreign analogues
Authors:   Kupper Group of Companies, Mamykin Sergey
Published: March 2023

The analysis of the current situation on the lubricants market in Russia is given, the problems and prospects of import substitution in the industry are noted. The author touches upon the technologies that the company uses in the production of lubricants, including its own copper clading technology — CLAD (Cuprum Lining Antiwear Defense), which provides the company with an advantage in the market.
Technology for developing a plan for the development of the OT-system of a food enterprise
Authors:   Constant Company. Nizhny Novgorod, Shishkin A.A.
Published: March 2023

The main industry automation systems of processes "1C:UPP" and "1C:ERP" are considered. The main stages of the implementation of the 1C:ERP system as an element of the digital transformation of an industrial enterprise on the example of the food industry are given.
The use of an alternative feed ingredient in the diet of pigs
Authors:   LLC Scientifi c Testing Center “Cherkizovo”, Russia, Moscow, Troitskiy AD, Novofedorovskoe, Kornilova E. V. , Nikolaev S. I. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Karapetyan A. K. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Chekhranova S. V ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Shkalenko V. V. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Danilenko I. Yu. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Kashyrina A. A. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd
Published: March 2023

The main grain feeds for animals in our country are still corn, wheat and barley. It is known that animals and poultry are competitors to humans in terms of grain consumption. Therefore, it is currently relevant in the fi eld of mono-gastric animals feeding to search for non-traditional feed sources. One of these is sorghum grain. The purpose of the work was to increase the live weight of young pigs when using low-cost compound feed with sorghum. We carried out a scientifi c and economic experiment at the LLC “TOPAGRO” enterprise in the Volgograd region on young pigs of three-breed hybrids. The animals of the control group received an farm diet with corn, and in the diet of the animals of the 1st, 2nd and 3rd experimental groups, 50, 75 and 100 % of corn was replaced with sorghum. In the feeding diet of pigs, partial or complete replacement of corn grain with sorghum of the variety Kamyshinskoe 75 contributed to an increase in the digestibility of nutrients compared with the indicators of analogues of the control group. The live weight of pigs on 119 days of experiment in the 1st experimental group was by 1,77 % higher than the control group, in the 2nd experimental group by 3,09 % (P > 0,95) and in the 3rd experimental group by 2,66 kg than in the control group. Control slaughter of animals has shown that the slaughter yield in the experimental groups was higher than in the control group from 0,53 to 0,91 abs.%. Thus, the replacement of corn grain with sorghum in the diets of pigs of the 1st, 2nd and 3rd experimental groups positively aff ected the digestibility of nutrients of compound feed and meat productivity of pigs.
Productive and biological traits of cows when including in the ration biological additives
Authors:   Kurgan Maltsev State Agricultural Academy – a branch of the Federal State Budgetary Educational Institution of Higher Education “Kurgan State University”, Russia, Kurgan region, Lesnikovo, Mikolaychik I. N. , Morozova L. A. ,   Kurgan Maltsev State Agricultural Academy – a branch of the Federal State Budgetary Educational Institution of Higher Education “Kurgan State University”, Russia, Kurgan region, Lesnikovo, Abileva G. U. ,   Kurgan Maltsev State Agricultural Academy – a branch of the Federal State Budgetary Educational Institution of Higher Education “Kurgan State University”, Russia, Kurgan region, Lesnikovo
Published: March 2023

At the present stage of the development of animal husbandry the fundamental factor in realizing the genetic potential of dairy productivity and preserving the health of cows is to provide animals with biologically complete feeding. The purpose of the work was to study the infl uence of biotechnological additives in the rations of highly productive cows on their productive and biological traits. The research was carried out in CJSC “Glinki” in the Kurgan region on highly productive cows of Black-and-White breed. The cows of the control group received the basic ration adopted on the farm. In addition to the basic ration the cows of the 1st experimental group were fed a probiotic additive Lactur at a dose of 2 kg/t of concentrated feed, the analogues of the 2nd experimental group were fed a prebiotic additive Acid Lac 3 kg/t of concentrated feed and the cows of the 3rd experimental group were fed together the probiotic additive Lactur 1 kg/t and the prebiotic additive AsidLak 1,5 kg/t of concentrated feed. The paper scientifi cally substantiates and experimentally confi rms the zootechnical and economic feasibility of the complex use of the probiotic additive Lactur and the prebiotic additive AcidLac in the rations of highly productive cows in order to increase their productive and biological traits. The use of biological additives in the rations of highly productive cows as part of concentrated feeds is economically feasible to increase the dairy productivity of cows, reduce the prime-cost of milk and increase the profitability of its production. A particularly positive eff ect was provided by the complex introduction of pro- and prebiotic feed additives into the ration of cows in the dry period and lactating cows, which positively affected their further productive traits during the period of increasing the milk yield and throughout lactation, which was confirmed by the increase in milk yields, fat and protein content in milk.
Reproductive traits of cows of Holstein breed and dynamics of their changes during productive life
Authors:   Federal State Budgetary Educational Institution of Higher Education “South Ural State Agrarian University”, Russia, Chelyabinsk region, Troitsk, Gritsenko S. A. , Kostomakhin N. M. ,   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow
Published: March 2023

In order to obtain maximum milk productivity of cows, it is necessary to constantly maintain a high level of reproduction traits of cows in the herd to ensure timely eff ective insemination of them for the annual production of calves. The economy of dairy farming, the level of breeding work, the longevity of animals depends on the state of reproduction of the herd. The purpose of the research was to study the reproductive traits of cows of Holstein breed and the dynamics of their changes during productive life. The research was carried out on the basis of the Agricultural Production Cooperative “Plamya”, a milk production enterprise where Holstein cattle are bred. In order to conduct the study, the indicators of the reproductive traits of cows of the entire productive herd were evaluated in dynamics over 5 years of production use. The material for the analysis of the dynamics of change was taken from the database of the information and analytical system “SELEX-Dairy cattle”. Thus, it was found that during the study period the annual calf crop increased by 102,4 % or by 2 calves. The average number of inseminations per effective one was 2,1 doses over the period. In the period from 2017 to 2021, in the herd the duration of the open days period ranged from 128 to 140 days. The best indicator was noted in 2019. On average, for the herd over a fi ve-year period, there was an increase in the duration of the open days period by 12 days compared to 2017 data. As a result of a comprehensive analysis of the state of reproduction traits of cows in the herd, it was found that the indicators of reproductive trais of cows had a slight deviation from the threshold (normative) values, which indicates a fairly high level of breeding work carried out by specialists of the farm.
Foreign experience of management in the field of agricultural development: history, current state, influence of digitalization
Authors:   Institute of System Research in Agro-industrial Complex of the National Academy of Sciences of Belarus, Republic of Belarus, Minsk, Kovalev I. L. , Kostomakhin M. N. ,   Federal State Budgetary Scientifi c Institution “Federal Research Center Agro Engineering All Russian Institute of Mechanization”, Russia, Moscow
Published: March 2023

The purpose of the work was to analyze the foreign experience of management in the fi eld of agricultural development: history, current state, the influence of digitalization. A number of highly promising modern trends in the development of agriculture in the world has been described in the article. In our days, the centralized management model in the development of rural areas and agribusiness still dominates in European countries, with all this the modern general approach of the policy of the EU and other European countries outside this union in regional development consists, first of all, in transferring as much management functions as possible to the regional level. This approach is also characteristic of the domestic model of agricultural development policy. The most important and eff ective tool (direction) of modernization of any of the known control systems in the modern world is their digitalization. Digitalization of management in the agricultural sector at all levels from the state to the subject of small agribusiness will not be an exception. Further digital transformation of management in domestic agriculture represents a higher level of digital integration, which affects the most complex organizational changes in government structures and agribusiness. The results of the implementation of these tasks would be able to dramatically affect the growth of profi ts in the agricultural business, the competitiveness of products and will allow the agricultural industry as a whole to reach the modern world technological frontiers.
Analisis Perhitungan Harga Pokok Produksi Pada Perusahaan Manufaktur Usaha Kecil (Studi Kasus: Perusahaan Cherryka Bakery Yogyakarta)
Authors: Kristrianto S. Prasetyo Andre , Marini Yushita
Published: March 2023

Today, cost accounting practices are needed for manufacturing companies, including companies engaged in bakery, both small and large companies. Cherryka Bakery is a small business manufacturing company in the production of various cakes and breads that calculates the cost of production using an order cost system for each bread order. In practice, where the calculation of the cost of production carried out by Cherryka Bakery only includes elements of direct raw materials and indirect raw materials, so it is considered less relevant to use an order cost system, therefore the author is interested in analyzing the calculation of the cost of production at Cherryka Bakery Yogyakarta. . This research uses qualitative methods on financial data sourced from Cherryka Bakery and field studies in conducting data analysis on the calculation of the cost of production and its application. The results of this study can be concluded that Cherryka Bakery's cost accounting system is still weak, so the authors suggest setting appropriate standard costs. with the needs of the elements of production and non-production costs from the specifications of each product so that it can be more in line with the characteristics of Cherryka Bakery.
Accounting Prudence Pada Perusahaan Bernotasi Khusus
Authors: Odang Nilam Kelama , Rangkuti Maryam Monika
Published: March 2023

Financial statements prepared using the accrual basis give rise to accounting prudence. The main factor that causes prudence to arise is conditions full of uncertainty, which creates caution, such as that caused by the Covid-19 pandemic. This study aims to analyze differences in accounting production before and during the Covid-19 pandemic for companies with special notations (2018 – 2021). The method used in this study is a quantitative method using the Paired T-Test for data analysis. The results of the study show that there is no significant difference between accounting prudence at companies with special notations before and during the Covid-19 pandemic.
Avances terapeúticos en atrofia muscular espinal
Authors: Di Rosa Rebeca Rodríguez , Ochoa Tania Pamela Barzallo , Vivar María Angélica Córdova , Iñiguez Mateo Nicolás Andrade , Ortiz Kevin Sebastian Criollo , Caraguay Sarahí Alejandra Vergara , Sanmartín Fausto Andrés Martínez , Avilés Christian Gonzalo Carpio
Published: March 2023

Antecedentes. La atrofia muscular espinal es una patología neurológica degenerativa hereditaria. Causa una degeneración paulatina de las motoneuronas de la asta anterior medular, también conocida como enfermedad de primera motoneurona. Como resultado, se genera debilidad y atrofia muscular progresiva. Afecta a 1 infante por cada 10000 nacidos vivos, por lo cual, es catalogado como una causa relevante de morbi-mortalidad infantil. A pesar de no existir cura actualmente, los medicamentos más conocidos son el nusinersen y el onasemnogén abaparvovec, actuando a nivel genético en el tratamiento de la enfermedad. Metodología. El presente estudio es una revisión tipo Scoping Reviw con metodología PICO y PRISMA utilizando la base de datos PUBMED a través de descriptores bibliográficos con la utilización de palabras clave aplicando criterios de elegibilidad de inclusión y exclusión. Objetivo. Detallar los nuevos avances terapéuticos para el manejo de la atrofia muscular espinal. Discusión y Resultados. Con un total de 17 artículos seleccionados se demostró que las nuevas opciones terapéuticas enriquecen las opciones médicas para tratar esta enfermedad, con menores costos y resultados exitosos a largo plazo. Conclusión. Es una de las enfermedades genéticas con más alta tasa de mortalidad alrededor del mundo. Un diagnóstico precoz mejora notablemente el pronóstico del paciente y permite tomar la decisión adecuada frente al tratamiento, asegurando la eficacia del mismo.
Uso da Bauhinia forficata no tratamento da Diabetes Mellitus: revisão integrativa
Authors: Lacerda Aline Alves Mendes , Duarte Ana Paula Ferreira , Miranda Eduarda Silva , Lobão Lúcia Meirelles
Published: March 2023

Existem, aproximadamente, 21.000 plantas medicinais, sendo 800 delas usadas para fins antidiabéticos. O presente estudo tem como objetivo apresentar uma atualização da efetividade da fitoterapia no tratamento do diabetes mellitus utilizando como referência a planta pata de vaca (Bauhinia forficata). Foi realizada uma revisão integrativa, através da busca de artigos nas bases de dados LILACS, MEDLINE e Google Acadêmico, utilizando os descritores “diabetes mellitus” AND “Bauhinia forficata” OR “pata de vaca”. Os artigos apontam redução dos níveis de creatinina, índice HOMA, LDL e colesterol total com o uso da planta. Desse modo, a efetividade na melhora dos sintomas da doença é comprovada, devido às propriedades farmacológicas apresentadas pela pata de vaca. Portanto, faz-se necessário que haja melhorias na implementação de políticas públicas e capacitação profissional para efetiva utilização da fitoterapia no tratamento de doenças crônicas.
A Study on the Progress of Iron-making Technology Development Identified at Donghae Songjeong-dong Remains
Authors:   The hoseo Archaeological Society, Choi Yeongmin
Published: March 2023

Donghae Songjeong-dong remains have been known as the important remains with regard to iron manufacture in the eastern region of Korea, but they have not been fully explored.
This study aggregated and re-examined the artifacts related with iron manufacture, excavated at Songjeong-dong remains, and the results of metallurgical analysis.
Archaeological materials include blast pipe, crucible, and furnace bottom, and the metallurgical analysis examined Songjeong-dong District Ⅱ and the remains of the trunk road site. The blast pipe is categorized into two types based on the caliber and thickness, and type Ⅱ was the same as the ones found among the articles excavated at Gapyeong Majang-ri remains. The crucible was the one used to produce cast ironware. The shape of the smelting furnace could be restored based on the examination of the furnace bottom. Results from metallurgical analysis evidenced the smelting technology.
Also, they also showed the progress of iron-making technology such as the introduction of the blast pipe for smelting and the cast ironware production technology. It is presumed that this iron-making technology was transmitted from the western region of Korea to the eastern region.
Periodization and Development of a Dwelling Cluster in Jungdo-dong, Chuncheon in the Bronze Age
Authors:   The hoseo Archaeological Society, Oh Kangwon
Published: March 2023

The dwelling cluster of Jungdo-dong is largely divided into six stages and eight periodization. The period from the Stage I(11th century BC) to the Stage Ⅲ(9th century BC) in Jungdo-dong was characterized by a combination of raised band decoration pottery, doublerimmed vessel, and rounded bottom upright rimmed pottery; a small-sized plain pit hearth dwelling and a medium and large-sized stone-lined hearth dwelling are combined in the Stage I(11th century BC), a large-sized stone-lined hearth dwelling and a plain pit hearth dwelling in the Stage Ⅱ(10th century BC), and lastly a small-sized plain pit health dwelling in the Stage Ⅲ (9th century BC). In addition to the small-sized plain pit hearth dwelling and the rim perforation decorated pottery, mandolin-shaped bronze daggers, various stone daggers, stone spearheads, stone arrowheads, etc. are associated in the Stage Ⅳ-1 (6th century BC), but in the Stage Ⅳ-2(5th century BC), the compacted medium-sized clay surface, the plain pit hearth dwelling, and artifacts similar to those of the Stage Ⅳ-1 are associated.
The compacted large-sized clay surface, the plain pit hearth dwelling, the rim perforation decorated pottery, etc. are combined in the Stage Ⅴ-1(4th century BC), the compacted middle-sized clay surface, the plain pit hearth dwelling, the rim perforation decorated pottery, the round attached-rim vessel, etc. in the Stage Ⅴ-2 (early to late 3rd century BC), and lastly the small-sized plain pit hearth, the hearth-free dwelling, the rim perforation decorated pottery, the round attached-rim vessel, etc. in the Stage Ⅵ(late 3rd century BC to mid 2nd century BC). The dwelling cluster of Jungdo-dong reached its peak in the Stage Ⅳ-2, which was clearly evident from the fact that the dwelling cluster in the Stage occupied 47% of the total area of Jungdodong.
The small-sized dwelling cluster in the Stage I had the smallest proportion, which was associated with the dwelling left over from the seasonal and temporary economic activities of the raised band decoration pottery group.
An Investigation of Preschool Teachers’ Use of Traditional Turkish Music in Music Activities
Authors: İnanıcı Murat Kamil , Sağer Turan
Published: March 2023

This study aims to determine to what extent preschool teachers include traditional Turkish music within the scope of music activities and what is the effect of this music on children. The study which was designed as qualitative research. A total of 50 preschool teachers, 92% of whom are female (n=46) and 8% are male (n=4), constitute the participants of the study. In the study, “semi-structured interview form” prepared by the researchers was used as a data collection tool. The obtained data were analyzed according to thematic analysis technique. The research findings were analyzed under four themes: “Likes and Use”, “Teaching”, “Developmental Contributions” and “Challenges and Solutions”. As a result of the research, it was found that preschool teachers partially included traditional Turkish music in their music activities, they did not receive training on teaching traditional Turkish music during their undergraduate education, children had various difficulties in vocalizing traditional Turkish music, and traditional Turkish music had development areas such as cognitive, psychomotor and language skills on children. It has been concluded that it has positive effects on the development of cultural memory and cultural transmission.
The Views of Middle School Students on Distance and Face-to-Face Education on Mathematics Education during the Covid-19 Pandemic
Authors: Baldemir Bilal , Tutak Tayfun
Published: March 2023

The spread of the Covid-19 all over the world have negatively affected many areas, leading to a number changes throughout the world. Being one of these areas, education had to undergone some changes and shifted to distance education during the Covid-19 pandemic. However, distance education has also brought some discussions and problems. This study was carried out to investigate the thoughts of middle school students on distance education and face-to-face education. Based on quantitative research design, this study adopted a phenomenological design Data were collected from a participant group consisting of 240 secondary school students (60 5th grade, 60 6th grade, 60 7th grade and 60 8th grade) through a scale prepared by the researchers. The data were analyzed using SPSS package program with descriptive statistics such as frequency and percentage. As a result of the study It was found that middle school students’ views on distance education and face-to-face education differed significantly with regard to parents’ education level, gender, grade level and average monthly family income.
Modeling and Control of the Extreme Ideology Transmission Dynamics in a Society
Authors: Azizah Nur , Bakhtiar Toni , Sianturi Paian
Published: March 2023

In this work, we propose a mathematical model to analyze the spread of extreme ideology in society. The so-called SERTA model divides the entire population into five compartments, namely susceptible, extremist, recruiter, treatment, and aware, to describe the state of the willingness of community members toward extreme ideology. We first present a model with constant control, i.e., a model without a dynamical control instrument, and provide the stability analysis of its equilibrium points based on the basic reproduction number. We then reformulate the model into an optimal control framework by introducing three control variables, namely prevention, disengagement, and deradicalization, to enable intervention of the dynamical process. The optimality conditions are obtained by employing Pontryagin's maximum principle, showing the optimal interdependence of state, co-state, and control variables. Numerical simulations based on the well-known Runge-Kutta algorithm and forward-backward sweep method are carried out to evaluate the effectiveness of control strategies under different scenarios. From the simulation results, it is found that by applying the three controls, the optimum solution is obtained. Besides that, in this study, disengagement contributes the most effect in suppressing extremist and recruiter populations, both by using single control and multiple controls.
Peramalan Data Cuaca Ekstrim Indonesia Menggunakan Model ARIMA dan Recurrent Neural Network
Authors: Hikmah Hikmah , Asrirawan Asrirawan , Apriyanto Apriyanto , Nilawati Nilawati
Published: March 2023

Extreme weather modeling is a challenge for modeling experts in Indonesia and the world. Extreme weather prediction is a complex problem because the chances of it happening are very small, so the developed models often have a low level of accuracy. The purpose of this research is to combine the classic model, Autoregressive Integrated Moving Average (ARIMA), recurrent neural network (RNN) model using Adam and SGD estimation (RNN-Adam and RNN-SGD) with the reLU, tanh, sigmoid and gaussian activation functions. In addition, the ARIMA-RNN mix model was also demonstrated in this study. These models are applied to monthly period extreme weather data obtained from the Meteorology, Climatology and Geophysics Agency (BMKG) of West Sulawesi Province which are converted into training data and test data. The RMSE value is used to see the level of prediction accuracy in both training data and test data. Based on the research results, the best model obtained for modeling Indonesia’s extreme weather is the ARIMA-RNN-Adam mix model with the reLU activation function based on the RMSE value on the training and test data. At n = 50, the smallest RMSE and MSE values of the third model are the ARIMA-RNN-Adam model which is 0.23212 using the reLU activation function, then the ARIMA-RNN-SGD model which is 0.25432 with the same activation function, while the ARIMA value is 0.3270. At n=100 it can be seen that the smallest RMSE and MSE values of the three models are the ARIMA-RNN-Adam model which is equal to 0.25149 using the reLU activation function, then the ARIMA-RNN-SGD model which is equal to 0.25256 with the same activation function, while the ARIMA value is 0.2644.