bluuebunny/crossref_metadata_2025 huggingface dataset:
Sivas İzzeddin Keykavus Darüşşifası Restorasyon Müdahaleleri
Authors: YİĞİTER Elif , KUNDURACI Osman
Published: June 2023

İzzeddin Keykavus Darüşşifası Sultan I. İzzeddin Keykavus tarafından 1217 yılında inşa edilmiştir. Darüşşifa işlevini Osmanlı döneminde devam ettiremeyen yapının vakıf şartları medrese hizmeti doğrultusunda değiştirilmiş ve 19. yüzyılın sonlarına kadar medrese olarak kullanılmıştır. Osmanlının savaşlarla geçen son dönemlerinde terk edilmiş, bakımsızlık sonucu bazı bölümleri yıkılmış ve büyük oranda tahrip olmuştur. 1930 sonrası eski eserlerin tescillenmesi ve onarılmasına yönelik çalışmalarla Darüşşifa’da koruma onarım programına alınmıştır. Bu kapsamda ilk çalışmalar 1938 yılı kazılarıyla başlamış, 1960 sonrası kapsamlı onarım çalışmalarıyla devam etmiştir. 1960-1970 yılları arasında gerçekleştirilen onarımlar bütünleme ve sağlamlaştırmaya yönelik olmuş, bugünkü çehresini ise 2009-2012 yılları arasındaki restorasyonlar ile kazanmıştır. Hem mimari özellikleri hem de vakfiyesiyle dönemi hakkında önemli bilgiler veren Darüşşifa’nın iyi bir şekilde korunması ve onarımlarının özenle yapılması gerekmektedir. Yapının özgün durumuna müdahale edilip edilmediği ise restorasyon çalışmalarının detaylı bir şekilde araştırılması sonucunda açıklık kazanacaktır. Bu kapsamda Darüşşifa’nın günümüze kadar geçirdiği çeşitli onarımlar ele alınmıştır. Ayrıca yapıda meydana gelen bozulmalar ve sebepleri tespit edilmiş, gerçekleştirilen onarımlar restorasyon tekniklerine göre değerlendirilmiştir.
Musaca Nekropolü Kazıları Cam Buluntuları
Authors: ELİÜŞÜK Mevlüt
Published: June 2023

Manisa ili Akhisar ilçesi Musaca mahallesi 103 ada, 1-2 parsellerde Gürdük Barajı yol güzergahı ve etki alanında, yol çalışmalarında tespit edilen nekropol alanında Manisa Müze Müdürlüğü’nce kurtarma kazılarında 34 mezar içerisinde 47 yetişkin bireye ait iskelet tespit edilirken, alanda bebek/çocuk mezarına rastlanmamıştır. Bebek/çocuk mezarlarının bulunmamış olması Thyateira kazılarında sadece çocuklara ait mezarların tespit edildiğinden, buradaki çocuk mezarlarının olasılıkla başka bir alanda olduğu ile açıklanmıştır. Musaca mahallesinin antik yerleşimi hakkında herhangi bir bulguya ulaşılamamıştır. Antik Dönem’de Polis’lerin hinterlandı dâhilinde ki tarımsal yerleşimler Kome olarak adlandırılmaktadır. Nekropolün 15 km güney batısındaki Thyateira “Akhisar” antik kenti varlığı olası Musaca yerleşim yerinin, Thyateira antik kentinin bir komesi olduğu anlaşılmaktadır. Nekropoldeki mezarlar basit toprak ve sandık mezar olarak iki grup altında değerlendirilmiş olsa da mezarların taş kapaklarının aynı olduğu anlaşılmıştır. Mezarlarda ele geçen cam buluntular unguentarium ve şişe olarak iki grupta değerlendirilmiştir. Buluntular ölü gömme ritüeli içerisinde libasyon ile ilişkilendirilmiştir. Mezarlardan ele geçen cam buluntular genel olarak MS 2-3. yüzyıllar arasına tarihlendirildiğinden, Musaca Nekropolü’nün kullanım dönemleri için de bu tarih aralığını vermek mümkündür. Tespit edilen cam formlarının Anadolu’nun genel cam tipolojisiyle uyumlu olduğu görülürken; şamdan biçimli unguentariumların yerel özellikler gösterdiği anlaşılmaktadır. Kırsal bir yerleşimdeki mezarlarda ele geçen cam eserlerin birebir benzerlerinin Bergama ve Tire gibi koleksiyonlarda belgelenmiş olması Batı Anadolu’da bu formların yaygın olarak kullanıldığını göstermektedir. Nekropolün yerleşim yeri tespit edilemediğinden kırsal alanda yaşayan halkın ekonomik durumu hakkında kesin yargıda bulunmak mümkün olmamakla birlikte mezar hediyesi olmayan örneklerin fazlalığı ve hediye bulunan mezarlardaki hediye sayısının azlığı, ekonomik seviyenin çok da iyi olmadığına da işaret etmektedir.
Sakinlerin Gözünden Huzurevi Yaşamını Anlamak
Authors: TAŞ Levent , CEBECİOĞLU Gülçin , KORKMAZ Ali Hikmet
Published: June 2023

Çalışmada yaşlı bireylerin huzurevi yaşamına bakışı ele alınmaktadır. Huzurevleri toplum açısından düşkün ve kimsesiz kişilerin yaşadığı yerler gibi görülür. Yaşlanmayla birlikte ortaya çıkan sosyal, psikolojik ve ekonomik vb. değişimler birçok dezavantaja neden olmaktadır. Huzurevleri ile yaşlıların karşılaştıkları dezavantajların ve sorunların en aza indirilmesi hedeflenmektedir. Özellikle barınma, beslenme ve güvenlik gibi ihtiyaçların karşılanmasında ortaya çıkan dezavantajların giderilmesinde huzurevlerinin pek çok katkısının olduğu düşünülmektedir. Bu konuda araştırmalar yapılmasına karşın huzurevi sakinlerinin huzurevi yaşamı hakkındaki düşünceleri akademik açıdan yeterli ilgiyi görmemektedir. Bu çalışmada sakinlerin gözünden huzurevi yaşamının özünün anlaşılması amaçlanmıştır. Bu amaçla katılımcıları huzurevi yaşamını tercihe götüren nedenlere ve huzurevi yaşamındaki deneyimlerine odaklanılmıştır. Araştırmada fenomenolojik nitel araştırma deseni benimsenmiştir. 2019 yılı Mayıs ve Haziran aylarında 21 katılımcı ile 30-60 dakika süren derinlemesine görüşmeler yapılmıştır. Verilerin analiz edilmesi sonucunda huzurevi sakinlerinin huzurevi yaşamını tercih etme sebepleri olarak ekonomik yetersizlik, sosyal destek ihtiyacı, huzur ve özgürlük arayışı tespit edilmiştir. Ayrıca sakinler huzurevi yaşamını gündelik ihtiyaçlarını rahatlıkla karşılayabildikleri konforlu bir yaşam olarak tanımlamaktadır. Ancak sakinlerin gözünde huzurevi yaşamının ailenin sağladığı sosyal ve psikolojik destekten yoksun bir yaşam olduğu anlaşılmaktadır. Bu temalar çerçevesinde huzurevi yaşamının özünün zorunluluk, konfor ve özlem kavramlarıyla tanımlanabileceği sonucuna ulaşılmıştır.
Mübadelenin Gücü: Kojin Karatani’de Kapitalizm ve Karşı Hareketler
Authors: DEMİRTAŞ Mustafa
Published: June 2023

Bu çalışmada, toplumsal formasyonların tarihini mübadele tarzları perspektifinden yeniden ele alan Kojin Karatani’nin felsefi ve politik görüşleri üzerine düşünmeyi deneyeceğiz. Karatani’ye göre kapitalizm, sermaye-ulus-devlet üçlüsüyle işleyen bir sistemdir; kapitalizmi anlamak ve ona karşı çıkmak için bu üçlüyü dikkate almamız gerekir. Bu çalışmada, sermayeye karşı girişilecek her eylemin devleti ve ulusu da karşısına alması gerektiğini belirten Karatani’nin kapitalizme ve ona karşı hareketlere dair görüşlerini inceleyeceğiz. Kapitalist ulus-devlet, oluşturduğu üçlü yapı sayesinde insanlığı geri dönülemez bir felakete sürüklediğinden bu felaketten çıkmak için Karatani’nin sunduğu imkânları ele alacağız. Siyasal ve sosyal düşüncede toplumsal formasyonların tarihi genellikle üretim kavramı etrafında düşünülür. Toplumsal formasyonların tarihini üretim kavramı yerine mübadele tarzları üzerinden düşünen Karatani’nin siyasal ve sosyal düşüncede farklı bir yerde durduğunu ileri süren bu çalışma, mübadele tarzları üzerinde duran Karatani perspektifinin sermaye birikim süreçlerine karşı çıkmaya çalışan toplumsal hareketler ve mücadele pratikleri açısından sonuçları olduğunu iddia eder. Bu iddia etrafında, bir yandan Karatani’nin sermaye-ulus-devleti aşmada ortaya koyduğu yaklaşımı sistemli ve eleştirel bir şekilde irdeleme fırsatı yakalar. Diğer yandan, üretimden ziyade mübadele tarzlarına odaklanmanın daha eşitlikçi ve özgürlükçü bir yaşam yaratmaya katkısını ortaya koyar.
Velid b. Abdülmelik Dönemi İmar Faaliyetleri
Authors: ŞİMŞİR Mehmet , DEMİR Kemal
Published: June 2023

Emevîlerin altıncı halifesi Velid b. Abdülmelik, hem kendi döneminde hem de sonraki süreç üzerinde önemli tesirler bırakan etkili bir kimsedir. Onun zamanında gerçekleştirilen fetih hareketleri sonucunda devletin siyasî sınırları doğuda Çin, batıda İspanya toprakları, kuzeyde İç Anadolu ve Kafkasya bölgesine kadar genişlemiştir. Bu sayede devletin gelirleri artmış ve hazinesi zenginleşmiştir. Velid b. Abdülmelik döneminde Ürdün ve Filistin topraklarını kapsayan bölge başta olmak üzere devletin birçok yerinde yoğun bir inşa faaliyetine girişilmiştir. Camiler, kasırlar inşa edilmiş, yeni şehirler kurulmuş, bazı bölgeler ihya edilmiş ve bazı eski yapılar onarılmıştır. Bu çalışmada Emevî halifesi Velid b. Abdülmelik döneminde (86-96/705-715) meydana gelen imar faaliyetleri üzerinde durulmuş, on yıllık süreç içerisinde yapılan imar faaliyetlerinin İslam sanat anlayışından ziyade daha çok nerede, ne zaman ve ne amaçla yapıldığı tespit edilmeye çalışılmıştır. Nitel araştırma yöntemi kullanılan çalışmada, öncelikli olarak literatür taraması yapılmış ve konuyla ilgili bilgi veren temel kaynaklar ile güncel araştırmalar tespit edilmiştir. Bu kaynaklardan doküman inceleme tekniğiyle elde edilen veriler betimsel olarak analiz edilmiştir. Tarihsel bilgileri ortaya koymanın yanı sıra konuyla ilgili yeni ve özgün çıkarımlarda bulunulmaya çalışılmıştır.
Risky is the New Safe
Authors: GİRAY Louie
Published: June 2023

Written by Randy Gage, Risky is the New Safe is an accessible, easy-to-read book that provides out-of-the-box insights on how to approach life, become successful, and live unconventionally through risking. Randy Gage is an American author, businessman, and motivational speaker, who is known for his inspiring rags-to-riches life story. Divided into seven chapters creatively named after parts of the opera, the main argument of the book is using the old, conventional, and safe paradigms is risky. It demands for a change in thinking and encourages the readers to act by embracing risk. It is not deadening and is recommended to decision-makers and to those who are interested in undertaking the risky and unconventional pathway.
Exploring the usefulness of the Brief COPE in clinical and positive psychology: A discriminant content validity study
Authors: Siaputra Ide Bagus , Rasyida Afinnisa , Ramadhanty Amanda Meuthia , Triwijati Noeroel Kentjono Endah
Published: June 2023

The Brief Coping Orientation to Problem Experienced (COPE) scale is widely used for measuring coping strategies. However, concerns persist regarding the dimensions captured by the scale and the accuracy of item representation. This study examined the relevance of adapted Brief COPE items using discriminant content validity (DCV). A panel of experts (n = 15) assessed the extent to which the items corresponded to their intended dimensions. Intraclass correlation (ICC) estimates ranged from 0.640 to 0.828, indicating agreement among experts. A one-sample t-test evaluated DCV, revealing that 21 out of 28 items distinctly and exclusively measured intended dimensions, confirming their discriminant content validity. Seven items were excluded: three did not measure coping strategies (non-dimension), and four measured them in different dimensions (wrong-dimension). The discriminant content-validated Brief COPE scale improves coping assessment, benefiting psychological therapies and providing researchers with refined measures for each coping strategy dimension, addressing dimensional concerns.
Physicochemical and microbiological quality of refrigerated raw bovine milk commercialized in Presidente Médici, Rondônia state, Western Amazon, Brazil
Authors: Rocha Viviane Gotardi , Guedes Gabriel Goes , Dantas Filho Jerônimo Vieira , Oliveira Antonia Valcemira Domingos de , Gasparotto Paulo Henrique Gilio , Cavali Jucilene , Pontuschka Rute Bianchini
Published: June 2023

The aimed was to evaluate the quality of raw milk from some suppliers in rural and urban areas and test the hypothesis that they are not safe for immediate consumption. The study was conducted with suppliers in rural and urban areas in Presidente Médici municipality, Rondônia state. The method of the Ministério da Agricultura, Pecuária e Abastecimento (MAPA), was used, which consists of titrating a portion of the sample with a sodium hydroxide solution of known concentration, using phenolphthalein as an indicator. According to Brazilian legislation and literature, stability of Alizarol, foreign substances, Chloride, Hypochlorite, Hydrogen Peroxide and Colostrum were analyzed. Microbiological analysis, standard plate count (SPC) and quantification of thermotolerant coliforms were also performed using the most probable number (MPN) technique. Values ​​above the limits established by legislation were found, mainly for temperature and titratable acidity, in addition to stability results against Alizarol and the presence of colostrum. There were high microbial contents with regard to SPC, and, in this case, the presence of pathogenic microorganisms cannot be disregarded. The presence of thermotolerant coliforms may indicate probable contact of milk with feces. Therefore, it is considered that the samples analyzed here are not safe for ingestion in the raw form.
Panorama da mineração brasileira em relação a alguns dos principais minerais críticos necessários à transição energética
Authors: Santos Yolacir
Published: June 2023

A necessária transição energética ao encontro de matrizes de baixo carbono que a sociedade atual vem vivenciando, ocasionará o aumento da demanda de diversos metais, tais como cobalto, cobre, níquel e lítio. Neste contexto, o presente artigo abordou os principais minérios portadores dos elementos, as reservas minerais brasileiras que porventura existam, os maiores produtores mundiais, a produção mineral brasileira, os principais projetos e requerimentos para estas substâncias protocolados na Agência Nacional de Mineração. Ao final, verificou-se que apesar do Brasil não estar entre os principais produtores em nenhum dos materiais, verifica-se a existência de extração mineral em solo brasileiro, exceção apenas em relação ao cobalto.
Identification of circRNA-miRNA-mRNA Network Regulated by Hsp90 in
Human Melanoma A375 Cells
Authors: Fu Qiang , Gao Hengyuan , Liu Kaisheng , Su Juan , Zhang Jianglin , Guo Xiaojing , Yang Fang
Published: June 2023

Background:

Melanoma is the deadliest form of skin cancer. Heat shock protein
90 (Hsp90) is highly expressed in human melanoma. Hsp90 inhibitors can suppress the growth of
human melanoma A375 cells; however, the underlying mechanism remains unclear.

Methods:

A375 cells were treated with SNX-2112, an Hsp90 inhibitor, for 48 h, and wholetranscriptome
sequencing was performed

Results:

A total of 2,528 differentially expressed genes were identified, including 895 upregulated
and 1,633 downregulated genes. Pathway enrichment analyses of differentially expressed mRNAs
identified the extracellular matrix (ECM)-receptor interaction pathway as the most significantly enriched
pathway. The ECM receptor family mainly comprises integrins (ITGs) and collagens
(COLs), wherein ITGs function as the major cell receptors for COLs. 19 upregulated miRNAs
were found to interact with 6 downregulated ITG genes and 8 upregulated miRNAs were found to
interact with 3 downregulated COL genes. 9 differentially expressed circRNAs in SNX-2112-
treated A375 cells were identified as targets of the ITG- and COL-related miRNAs. Based on the
differentially expressed circRNAs, miRNAs, and mRNAs, ITGs- and COL-based circRNAmiRNA-
mRNA regulatory networks were mapped, revealing a novel regulatory mechanism of
Hsp90-regulated melanoma.

Conclusion:

Targeting the ITG-COL network is a promising approach to the treatment of melanoma.
Zero-valent Iron Nanoparticles: Biogenic Synthesis and their Medical
Applications; Existing Challenges and Future Prospects
Authors: Hayat Minahil , Bukhari Sayyad Ali Raza , Ashraf Muhammad Irfan , Hayat Sumreen
Published: June 2023

Objective:

In the last decade, nanobiotechnology is emerging as a keen prudence area
owing to its widespread applications in the medical field. In this context, zero-valent iron nanoparticles
(nZVI) have garnered tremendous attention attributed to their cheap, non-toxic, excellent
paramagnetic nature, extremely reactive surface, and dual oxidation state that makes them excellent
antioxidants and free-radical scavengers. Facile biogenic synthesis, in which a biological
source is used as a template for the synthesis of NPs, is presumably dominant among other physical
and chemical synthetic procedures. The purpose of this review is to elucidate plant-mediated
synthesis of nZVI, although they have been successfully fabricated by microbes and other biological
entities (such as starch, chitosan, alginate, cashew nut shell, etc.) as well.

Methods:

The methodology of the study involved keyword searches of electronic databases, including
ScienceDirect, NCBI, and Google Scholar (2008-2023). Search terms of the review included
‘biogenic synthesis of nZVI’, ‘plant-mediated synthesis of nZVI’, ‘medical applications of
nZVI’, and ‘Recent advancements and future prospects of nZVI’.

Results:

Various articles were identified and reviewed for biogenic fabrication of stable nZVI with
the vast majority of studies reporting positive findings. The resultant nanomaterial found great
interest for biomedical purposes such as their use as biocompatible anticancer, antimicrobial, antioxidant,
and albumin binding agents that have not been adequately accessed in previous studies.

Conclusion:

This review shows that there are potential cost savings applications to be made when
using biogenic nZVI for medical purposes. However, the encountering challenges concluded later,
along with the prospects for sustainable future development.
Manufacturing and Applications of Cellulosic Films in Packaging:
An Alternative for Plastic Films
Authors: Akhtar Saamir , Gupta Arun Kumar , Kumar Himanshu
Published: June 2023

Background:

Different synthetic materials are constantly being utilized as raw materials
for packaging, which might have several drawbacks, like plastic, some of which have poor
lifespans. Plastic can get damaged, scratched, or fractured over time, easily take in tastes and fragrances,
and significantly affect the environment and health. Excessive plastic waste may lead to
environmental pollution and related consequences. Plastics that contaminate food have also been
linked to health problems like high blood pressure, heart palpitations, headaches, nausea, diarrhea,
and flushing.

Objective:

The present review entails the hazards associated with the usage of plastic as a packaging
material and highlights the necessity to reduce its use and promote alternatives and sustainable
production. Thus, the present review portrays the need for biopolymers, types of plant polymers,
methods of cellulose extraction and derivatization, the manufacturing process of cellulosic films
and thereby use as film and coatings for food preservation. The current review also summarizes
different quality control tests for effective utilization as an alternative to synthetic polymers.

Conclusion:

Different polymers derived from agricultural products are excellent candidates for
creating packaging materials. Similar to polysaccharides, these polymers, including nanocomposites,
films, composites, etc., are helpful in a wide range of applications. Cellulose, one of the most
widespread polysaccharides in the world, offers a variety of appealing special qualities. It appears
reasonable and must be considered that cellulose can be used effectively as a raw material for packaging.
In this review, we explore how cellulose is used in the packaging industry to make composites,
coating materials, and edible and non-edible films.
The Effect of DNA Concentration on the HRM Performance in Detecting
Jak2 p.V617F Variant in Patients with Myeloproliferative Neoplasms
Authors: Soltani Atefeh , Shariati Aref , Didehdar Mojtaba , Anoushirvani Ali Arash , Tabaeian Seidamir Pasha , Moradabadi Alireza
Published: June 2023

Introduction:

Janus kinase 2 (JAK2) is an intracellular signaling protein. JAK2 p.
V617F is a common variant in normal karyotype myeloproliferative neoplasms (MPN). Highresolution
melting (HRM) analysis is one of the essential methods for detecting the JAK2 p.V617F
variant. In this study, we have investigated the effect of DNA concentration on detecting the JAK2
p.V617F variant using the HRM method.

Methods:

Genomic DNA was extracted from human blood and diluted ten times in distilled water
from 1 to 0.03; afterward, HRM was conducted for each dilution (triplicate). Using SPSS v.20.0
software, the mean Tm of each dilution was calculated and compared.

Results:

The HRM results revealed the JAK2 wild type and variant to have Tms of 81/64°C and
80/76°C, respectively. At the endpoint of the pre-amplification, the dilutions had different emissions.
The statistical analysis revealed no statistically significant differences in Tm between samples
with varying DNA concentrations (P value > 0.05).

Conclusion:

There have been no significant differences obtained in the analysis of JAK2 p.V617F
point variant in different DNA dilutions, implying that the HRM analysis has no relation to DNA
concentration.
Phytochemical-based Nanoformulations for Drug-resistant Brain Cancer
Authors: Saini Neha , Bhatt Shailendra , Kumar Manish
Published: June 2023

Background:

Brain tumor is the deadliest to treat with conventional drug therapy as it has
various side effects on patients leading to organ failure.

Objective:

It is difficult to treat brain cancers or deliver drugs to the targeted organ due to the numerous
challenges faced. The current cytotoxic drugs have serious side effects, such as causing extreme damage
to healthy cells, anemia associated with bone marrow suppression, constipation, small intestine infection,
inflammatory responses, immunodeficiency, and multiorgan toxic effects. Low solubility, poor cell penetration,
hepatic disposition, narrow therapeutic index, and rapid uptake by normal tissues are also a few
challenges. To overcome these issues, it is important to choose plant-based drugs in nano-formulations to
inhibit tumor cell growth without harming the normal cells of an individual. The biggest challenge in
treating tumors is multidrug resistance, which can be overcome by choosing combination therapies of
drugs based on phytochemicals and chemotherapeutic agents, which may lead to minimized adverse effects
on patients with brain tumors.

Results:

As the use of nano-technology for targeted delivery enhances the performance of chemotherapeutic
agents, the drugs with poor characteristics can further be encapsulated in nano-carriers and easily
delivered to the poorly accessible areas of the brain.

Conclusion:

Based on the current progression in nanoformulations, so many new therapeutic approaches
are available to provide better therapeutic results. However, there seems to be a multitude of issues that
need to be addressed in order to ensure efficient results in treating cancer and thus lessening the fatality
rate.
Implementation of Lean management Practices in Azerbaijan (on the Example of a Private Company)
Authors: Alaskarova Yelena , Aleskerova Alina , Dr. Daróczi Miklós
Published: June 2023

Organizations are facing crucial modifications as global market and conditions change day after day. To keep up with fast changing realities, it’s important to apply innovation decisions to the current stage of organizations. Lean management consolidates tools and techniques to revert from traditional way of operating to the new human oriented one. In the carried-out research its outlined, human resources management plays a big role in spreading and supporting lean initiatives. It was suggested that, Lean and Human resources management are compatible and should work together to obtain sustainable success by implementation of an innovation approach such as Lean.  Both lean management and human resource management focus on the same goals with different methods in terms of control of businesses. All positivist approaches and practices are included in these approaches and practices, which are developed with a focus on the interests of the community, in order for the process to be concluded positively. The employee-centred management approach of human resources management is crucial to lead and maintain good environment in the teams. For this reason, in the lean management philosophy, it is aware that the corporate structure has responsibilities in terms of training the employees, eliminating their problems and supporting them in struggling with the responsibilities they undertake. This paper is quantitative, online survey has been conducted with employees of a private company in Azerbaijan and results were analysed in statistical analysis software SPSS and relevant suggestions and recommendation were given for reorganization to enable lean friendly environment on a sample of the given company.
Keywords: Contineous improvement, Human resources management, Industry 4.0, Lean Managament, Lean philisophy.
The Influence of the Boundary Conditions on the Buckling of Thin-walled Cans during Manufacturing
Authors: Gönczi Dávid
Published: June 2023

In this paper the effect of the boundary conditions on the stability of thin-walled aerosol cans under axial pressure is investigated. The main objective is to outline the main characteristics of this highly nonlinear mechanical problem and to present methods to simulate the buckling of cans with different boundary conditions. Due to the numerical difficulties coming from the contact between the can and different components of the machines, the effect of the different supports of the can is investigated on the crushing (or buckling) force at which the loss of stability occurs. The commercial finite element software Abaqus is used to solve the problems and to present the efficiency of FE codes in the design process of cans.
Roguelike games
Authors: Orbán Szabolcs Gergely , Szabados György Norbert , Bácsné Bába Éva , Fenyves Veronika , Bács Zoltán , Molnár Anikó , Ráthonyi Gergely , Rizwan Hussain
Published: June 2023

The spread of the gameable personal computers and game consoles resulted in the diversification of the video game genre, and from the 7th generation of the gaming consoles, the experience support of the games became largely enhanced. These games are now consumable owing to their resolution, the content, the plots are so fascinating so that they tie the gamer to the seat. Gamers seek experiences in the games. Still, such a special genre called roguelike was established, which is characterized by the constant termination of this world of experience in such a way that the gamer, as a results of the high level of difficulty, is obliged to start the game again and again. These new genre games are now leading titles of the new generation consoles, such as Demon’s Souls or the Returnal, gaining huge role in the introduction and sale of the new gaming console PS5. This study aims to reveal specifications of this genre, moreover, aims to describe through empirical research how gamers relate to it, and whether features of these games contribute to the devotion to them or lead to the disappointment from this world of experience.
Электромагнитно-индуцированная прозрачность в ячейках конечных размеров с антирелаксационным покрытием стенок
Authors: Волошин Г.В.
Published: June 2023

In this paper, we propose an approach that makes it possible to obtain an analytical expression of the spectral dependence of the resonance of electromagnetically induced transparency detected by bichromatic radiation in a cell of finite size in the longitudinal direction of the laser beam. Specular and diffuse reflections of atoms from walls are considered. It was found that a significant difference between these types of reflections takes place only for cells of small longitudinal dimensions compared to the splitting wavelength of the ground state of atoms. A physical explanation is proposed for the difference between the Stokes and anti-Stokes scattering channels of probe radiation in terms of dressed states.
Оптическая спектроскопия ионов Er-=SUP=-3+-=/SUP=- в кристаллах BaY-=SUB=-1,8-=/SUB=-Lu-=SUB=-0,2-=/SUB=-F-=SUB=-8-=/SUB=-
Authors: Астраханцева А.В. , Шавельев А.А. , Кузнецов С.В. , Николаев А.Г. , Болдырев К.Н. , Низамутдинов А.С. , Семашко В.В.
Published: June 2023

The spectral and kinetic characteristics of Er3+ ions in heavily doped BaY1.8Lu0.2F8 mixed crystals have been studied. Absorption and luminescence spectra were recorded for BaY1.8Lu0.2F8 crystals with Er3+ ion concentrations of 20.0 and 30.0 at.%. The kinetic dependences of luminescence decay in the infrared range have also been studied. A model of the level populations of Er3+ ions is constructed on the basis of a three-level scheme for pumping the 4I11/2 state at a wavelength of 970 nm without taking into account up-conversion processes. The gain of BaY1.8Lu0.2F8 crystals with Er3+ ion concentrations of 20.0 and 30.0 at.% is estimated at different pump powers.
Оптические и люминесцентные свойства керамик MgAl-=SUB=-2-=/SUB=-O-=SUB=-4-=/SUB=-, активированных ионами Eu в высокой концентрации
Authors: Валиев Д.Т. , Хасанов О.Л. , Двилис Э.С. , Пайгин В.Д. , Линь Ч. , Степанов С.А.
Published: June 2023

The series of MgAl2O4 ceramics doped with high level of europium oxide (Eu2O3) up to 15 wt.% was fabricated by the Spark Plasma Sintering technique. The prepared ceramics have been tested using the various experimental techniques: X-ray diffraction, scanning electron microscopy, as well as optical and cathodoluminescence spectroscopy. The influence of europium oxide on the complex of optical and luminescent characteristics of MgAl2O4:Eu ceramics is discussed. The nature of the luminescence centers and the luminescence decay parameters are considered in detail.
Новые апконверсионные объемные и нанолюминофоры на основе Sr-=SUB=-2-=/SUB=-Y-=SUB=-8-x-y-=/SUB=-Yb-=SUB=-y-=/SUB=-Tm-=SUB=-x-=/SUB=-Si-=SUB=-6-=/SUB=-O-=SUB=-26-=/SUB=-
Authors: Зуев М.Г. , Васин А.А. , Ильвес В.Г. , Соковнин С.Ю.
Published: June 2023

Polycrystalline phosphors with a Sr2Y8-x-yYbyTmxSi6O26 (x=0.005-0.5, y=0.2,0.3) total formula were synthesized. Nanoluminophor has been obtained from the Sr2Y7.695Yb0.3Tm0.005Si6O26 microcrystalline sample by the vacuum electron been evaporation, in the amorphous state, with the ~10.6 nm particle size. It is found, raman spectra undergoing modification by the transition from bulk- to nanosize state. Photoluminescene spectra micro- and nanophosphors are studied. Intensity of the blue emission, by the UV ligth excitation, grows in the x=0.005-0.02 region, with the x increasing. Upconversion photoluminescence (UPCL) spectra of the bulk phosphors and nanosample based on the Sr2Y7.695Yb0.3Tm0.005Si6O26 were measurd. At the pumping power around 70.8 mW, by the laser source with the λ=980 nm, thereshold population of the 3F3 level of Tm3+ ions exist. At a power higher 70.8 mW, a sharp increase of the luminescence intensityof the bulk- and nanophosphor occurs. For the 3H4->3H6 transition thereshold pumping power absent. This indicates that, pumping, during Yb->Tm energy transer, is a single photon process.
Actividad cicatrizante del extracto hidroetanólico liofilizado de Piper angustifolium en cuyes con lesiones subcutáneas y dérmicas
Authors: Carhuapoma-Delacruz Victor , Huaman Cusi Brian , Maldonado Chilquillo Janeth Vanessa , Soldevilla Choque Luis Mariano , Quispe Gaspar Maricruz , Valencia Mamani Nicasio , Jurado Escobar Melanio , Esparza Mario
Published: June 2023

Las lesiones subcutáneas y dérmicas en cuyes (Cavia porcellus) son de importancia clínica, sin embargo, su tratamiento no ha sido eficaz con productos veterinarios tradicionales. Por lo anterior, se evaluó la actividad cicatrizante del extracto hidroetanólico liofilizado de Piper angustifolium a diferentes concentraciones en cuyes con lesiones subcutáneas y dérmicas, así como el costo del tratamiento. Se emplearon 92 cuyes hembras de raza Perú de seis meses de edad con heridas subcutáneas y dérmicas, previo examen clínico. Los grupos consistieron: G1-M 40 %, G2-M 70 %, G3-CP y G4-CN. Se aplicaron a animales del G1 y del G2 a concentración de 40 % y 70 % de extracto etanólico de matico y del G3 violeta de genciana por vía tópica durante 15 días. El tratamiento G2 demostró ser eficaz en cicatrización a los 10 días en relación con G1 y G3. El tiempo y el diámetro de cicatrización mostraron diferencias significativas (p < 0,05), en G2 fue de 0,04 ± 0,1c a los 10 días de estudio, siendo inferiores a G3 (0,80 ± 0,1a) y G1 (0,36 ± 0,4c). El menor costo/tratamiento (dólares estadounidenses) fue para G2 ($1,80) con respecto a G1 ($2,5) y G3 ($3,2) y el extracto hidroetanólico liofilizado de 70 % de Piper angustifolium resultó ser un eficaz cicatrizante en lesiones subcutáneas y dérmicas en cuyes, a menor costo en relación con los tratamientos convencionales.
Customer satisfaction survey, menu development and HACCP training to improve the food service quality of canteens
Authors: Budiningsari Dwi , Helmiyati Siti , Wisnusanti Setyo Utami , Lestari Lily Arsanti , Putie Sridanti Annissa
Published: June 2023

Canteen is an important aspect of the food environment in providing healthy food and supporting good nutrition status. The food service quality of the canteens could be improved by customer satisfaction survey and followed up with staff training. This study aimed to measure customer satisfaction via surveys and identify the impact of menu development training as well as HACCP training for canteen staff. The survey was collected using an online form involving 1,022 customers. The training was attended by 31 canteen staff. In addition to menu development-training, we also conducted Hazard Analysis Critical Control Point (HACCP) training. Menu development training includes topics such as menu variation, creating new recipes, and food traffic light system. A descriptive post evaluation was conducted to evaluate the impact of the training. A 6-question survey to assess how well the canteen staff retained knowledge from the provided food safety training were performed. From the survey, it was obtained the mean score for each indicator as follows: 3.32 for food taste, 3.22 for menu variation, 3.48 for canteen hospitality, 3.43 for canteen cleanliness, and 3.14 for food prices. The staff gave responses that the training was useful to increase foodservice quality and board the healthy food knowledge of canteen staff. Food traffic light systems that were placed in front of the counters could help customers to choose healthier foods. The results of HACCP training showed that all participants got more than half of the questions right. The responses of surveyed staff members suggest that the training was useful in increasing food service quality as well as food safety knowledge and practices of canteen staff. Sustainability of training impacts should be evaluated to gain comprehensive evaluation and identify further intervention to improve the food quality of canteens.
Analysis of blood donors’ characteristics during third-peak COVID-19 in Bojonegoro Regency, Indonesia
Authors: Nurkasanah Siti -
Published: June 2023

The third peak of Coronavirus disease 2019 (COVID-19) in Indonesia was recorded on February-March 2022 had an impact on voluntary blood donors at the Indonesian Red Cross (IRCS) Bojonegoro. The objective of this research was to analyze the blood donors’ characteristics during third-peak COVID-19 in Bojonegoro Regency. This research was descriptive analysis study using secondary blood donor data from February 22, 2022 to March 19, 2022 at IRCS Bojonegoro. The data was collected in donor selection process accordance the Indonesian and WHO blood donor selection guidelines. The average number per daily blood donors was tested using the Mann-Whitney-U test using IBM SPSS type 23 software with significancy p<0.05. The results showed there were 219 people (80.51%) on 22-28 February and 332 people (83.63%) on 1-19 March 2022 who approved to donate at IRCS Bojonegoro. There was a significant decrease in the average of daily male blood donors (p=0.01), average age group: 17-24 years (p=0.013), 35-44 years (p=0.002), and 45-54 years (p=0.030), hemoglobin (Hbl) levels on 16.1-17 g/dL (p=0.000), systolic blood pressure (SBP) <120 (p=0.03) and 130-139 (p= 0.02) and diastolic blood pressure (DBP) <80 (p=0.001), pulse rate (PR) 65-74 beats/minute (p=0.016), and blood type O+ (p=0.008). The characteristics of blood donors at the third peak of COVID-19 in Bojonegoro Regency decreased significantly in the number of male blood donors, age group, SBP, DBP, PR, and O+ blood type.
Add-on Rehmannia-6–Based Chinese Medicine in Type 2 Diabetes and CKD
Authors: Chan Kam Wa , Kwong Alfred Siu Kei , Tan Kathryn Choon Beng , Lui Sing Leung , Chan Gary C.W. , Ip Tai Pang , Yiu Wai Han , Cowling Benjamin John , Taam Wong Vivian , Lao Lixing , Feng Yibin , Lai Kar Neng , Tang Sydney C.W.
Published: June 2023

Background

Diabetes is the leading cause of CKD and kidney failure. We assessed the real-world effectiveness of Rehmannia-6–based Chinese medicine treatment, the most used Chinese medicine formulation, on the change in eGFR and albuminuria in patients with diabetes and CKD with severely increased albuminuria.

Methods

In this randomized, assessor-blind, standard care–controlled, parallel, multicenter trial, 148 adult patients from outpatient clinics with type 2 diabetes, an eGFR of 30–90 ml/min per 1.73 m2, and a urine albumin-to-creatinine ratio (UACR) of 300–5000 mg/g were randomized 1:1 to a 48-week add-on protocolized Chinese medicine treatment program (using Rehmannia-6–based formulations in the granule form taken orally) or standard care alone. Primary outcomes were the slope of change in eGFR and UACR between baseline and end point (48 weeks after randomization) in the intention-to-treat population. Secondary outcomes included safety and the change in biochemistry, biomarkers, and concomitant drug use.

Results

The mean age, eGFR, and UACR were 65 years, 56.7 ml/min per 1.73 m2, and 753 mg/g, respectively. Ninety-five percent (n=141) of end point primary outcome measures were retrievable. For eGFR, the estimated slope of change was −2.0 (95% confidence interval [CI], −0.1 to −3.9) and −4.7 (95% CI, −2.9 to −6.5) ml/min per 1.73 m2 in participants treated with add-on Chinese medicine or standard care alone, resulting in a 2.7 ml/min per 1.73 m2 per year (95% CI, 0.1 to 5.3; P = 0.04) less decline with Chinese medicine. For UACR, the estimated proportion in the slope of change was 0.88 (95% CI, 0.75 to 1.02) and 0.99 (95% CI, 0.85 to 1.14) in participants treated with add-on Chinese medicine or standard care alone, respectively. The intergroup proportional difference (0.89, 11% slower increment in add-on Chinese medicine, 95% CI, 0.72 to 1.10; P = 0.28) did not reach statistical significance. Eighty-five adverse events were recorded from 50 participants (add-on Chinese medicine versus control: 22 [31%] versus 28 [36%]).

Conclusions

Rehmannia-6–based Chinese medicine treatment stabilized eGFR on top of standard care alone after 48 weeks in patients with type 2 diabetes, stage 2–3 CKD, and severely increased albuminuria.

Clinical Trial Registry

Semi-individualized Chinese Medicine Treatment as an Adjuvant Management for Diabetic Nephropathy (SCHEMATIC), NCT02488252.
Assessing the English Speaking Self-Efficacy of Translation-Major Undergraduates: A Current Perspective
Authors: Yuehua Huang , Qiumei Wang
Published: June 2023

Self-efficacy is a vital determinant of students’ future accomplishments or setbacks and has been recognized as a significant influencer of their motivation to learn, intimately linked with academic achievement. Nonetheless, English learners often grapple with a lack of self-efficacy in their speaking skills. In order to investigate the current state of undergraduate translation students’ English speaking self-efficacy, a quantitative research design, coupled with a survey strategy, was employed. This investigation involved data gathered from 163 undergraduate translation students across three universities located in Guangxi, China. The findings reveal that translation-major undergraduates possess a moderate level of English speaking self-efficacy. Intriguingly, there were no noticeable differences in speaking self-efficacy and its three dimensions based on the academic year, indicating consistency in speaking self-efficacy across different academic levels. The gender-based comparison also yielded interesting results. There was no significant disparity in English speaking self-efficacy between male and female students. However, when it came to self-regulated self-efficacy—a crucial aspect of autonomous learning—female students significantly outperformed their male counterparts. Drawing from these research outcomes, this paper proposes targeted recommendations to enhance English speaking self-efficacy among undergraduate translation students.
Body and appearance-related self-conscious emotions and disordered eating in a simple of adult men/Emociones autoconscientes relacionadas con el cuerpo y la apariencia y trastornos alimentarios en una muestra de hombres adultos
Authors: Mendia Jara , Borreguero Nerea , Pascual Aitziber , Conejero Susana
Published: June 2023

En los últimos años, ha aumentado el número de hombres que padecen un Trastorno de la Conducta Alimentaria (TCA). Sin embargo, apenas se han realizado estudios sobre TCA con muestras de hombres. Este trabajo pretende arrojar algo de luz a este respecto, explorando las siguientes cuestiones en una muestra de hombres adultos: 1) analizar las relaciones entre las emociones autoconscientes asociadas al cuerpo y a la apariencia y la sintomatología de TCA y, 2) estudiar las diferencias entre un grupo de hombres que están en riesgo de desarrollar un TCA y otro grupo de hombres que no presentan dicho riesgo en las emociones autoconscientes asociadas al cuerpo y a la apariencia. Participaron 207 hombres de entre 18 y 50 años de nacionalidad española o latinoamericana. Los hombres que estaban en riesgo de desarrollar un TCA presentaron más vergüenza corporal y culpa corporal que aquellos que no tenían dicho riesgo. Sin embargo, no se encontraron diferencias estadísticamente significativas entre ambos grupos en el orgullo corporal. Estos hallazgos muestran que, a diferencia de lo que ocurre en mujeres, el orgullo corporal no parece desempeñar un papel tan relevante en estos trastornos como el que tienen la vergüenza corporal o la culpa corporal.
Accountable Proxy Re-Encryption for Secured Data Sharing
Authors: V Bhuvaneshwari
Published: June 2023

Abstract: Proxy re-encryption (PRE) provides a promising solution for encrypted data sharing in public cloud. When data owner Alice is going to share her encrypted data with data consumer Bob, Alice generates a re-encryption key and sends it to the cloud server (proxy); by using it, the proxy can transform Alice’s ciphertexts into Bob’s without learning anything about the underlying plaintexts. Despite that existing PRE schemes can prevent the proxy from recovering Alice’s secret key by collusion attacks with Bob, due to the inherent functionality of PRE, it is inevitable that the proxy and Bob together are capable to gain and distribute Alices decryption capabilities. Even worse, the malicious proxy can deny that it has leaked the decryption capabilities and has very little risk of getting caught. To tackle this problem, we introduce the concept of Accountable Proxy ReEncryption (APRE), whereby if the proxy is accused to abuse the re-encryption key for distributing Alice’s decryption capability, a judge algorithm can decide whether it is innocent or not. We then present a non-interactive APRE scheme and prove its CPA security and accountability under DBDH assumption in the standard model. Finally, we show how to extend it to a CCA secure one.
Assessment of Use of Pozzocrete on Strength of Concrete
Authors: Deepak Gunjagi
Published: June 2023

Abstract: Concrete demand has increased to satisfy the need of infrastructural development facilities. Tremendous amount of natural resources and energy is consumed for production of ordinary Portland cement. It also emits substantial quantity of carbon dioxide into the atmosphere. Therefore, it has been need of the hour to find out alternatives for making eco-friendly concrete. Many siliceous and alumnio-siliceous material are available which possess little or no binding values. But these materials in finely divided forms when come in contact with moisture, they chemically react with calcium hydroxide to form compounds those have binding properties. In the current studies when research was conducted on pozzocrete in laboratory it was well established that when pozzocrete is used in concrete, it increases the strength of concrete. Pozzocrete being finer than cement, gives more specific surface, fills the voids, increases workability of concrete and also reduces the problem of shrinkage in concrete. In the current study, the behavior of pozzocrete with cement concrete is reported. Percentage variation of pozzocrete in cement concrete to replace cement is tested to achieve economy as well as higher strength of RCC structural members. An experimental investigation was carried out on pozzocrete in reinforced cement concrete. Weigh batching method was used for 10% to 30% replacement of cement by pozzocrete in M20 grade concrete. It was found out that 30% replacement of cement with pozzocrete gave most acceptable results in flexural behavior. Workability and ductility of concrete was also found to be increased with increase in flexural strength.
Survey Paper on Big Data Technologies
Authors: Joshi Priti
Published: June 2023

Abstract: In the 21st century with the tremendous increase in the usage of internet and extreme advancement in Technology huge amount of Data is generated every second. This Data is combination of structured semistructured and unstructured data which is called as Big data. Being able to use this data provides huge opportunities and to turn these opportunities into reality, people need to use data to solve problems. Handling Big data has various challenges like Storage, Search, analysis, sharing, visualization, transfer and privacy violations. Big data analytics can help better and faster decision making, modeling and predictive analysis for enhanced business intelligence.
Development and Validation of Simultaneous Spectroscopic Method for Tetracycline Hydrochloride and Clotrimazole
Authors: Mishra Janhavi
Published: June 2023

Abstract: A simple and accurate simultaneous method was developed for tetracycline hydrochloride (TH) and clotrimazole with a mixture of solvents. the combination is used to Validate the developed UV-spectrophotometric method as per ICH guidelines, The concentration of Tetracycline hydrochloride & clotrimazole in the sample solution was determined by solving the respective simultaneous equations generated by using absorptivity coefficients and absorbance values of TH & Clotrimazole at these wavelengths 361 nm and 259 nm respectively. and both satisfy Beer's law in concentration ranges of 4-20 µg/ml for TH and 10- 30 µg/ml for Clotrimazole. The method was effectively used to estimate TH and clotrimazole in Buccal film without the interference of common excipients.