bluuebunny/crossref_metadata_2025 huggingface dataset:
CORRELATION BETWEEN ECONOMIC GROWTH AND PUBLIC DEBT LEVEL IN SELECT COUNTRIES OF THE EUROPEAN UNION
Authors: Sobczak Wioleta , Radziewicz Elżbieta
Published: July 2021

The complex correlation between public debt and economic growth is very important and is a focus of research within the scientific community and among policy makers. The main purpose of this paper is to identify the correlation between the level of public debt and the level of economic growth in select European Union countries. It is an empirical study of the transmission mechanisms and impact of public debt on economic growth in countries which joined the European Union in 2004 or later. The time range of the analyses covers the years 2000–2019. Estimation of the model parameters shows that the level of public debt had an impact on economic growth only in some countries.
OPPORTUNITIES FOR SELF-FINANCING THE USE OF HIGH-YIELDING SUNFLOWER SEEDS AMONGST SMALLHOLDER FARMERS IN TANZANIA: PERCEPTIONS VS. REALITY OF LIQUIDITY LIMITATIONS
Authors: Tibamanya Felister Yakobo , Kuzilwa Joseph Andrew , Mpeta Daniel Fabiano
Published: July 2021

This paper investigates the opportunities for smallholder farmers to self-finance the use of high-yielding sunflower seeds, by considering their marketable noncommercial asset levels and their perceptions versus the reality of liquidity limitations. The study used a cross-sectional survey covering 416 randomly selected smallholder sunflower farmers in the study area of Tanzania. It makes use of the crafted choice experiment approach to assess the degree of liquidity constraints among smallholder farmers in buying high-yielding seeds, and their willingness to receive a low-interest credit or loan to purchase high-yielding seeds given before or after sowing. Results reveal that liquidity limitation is a perceived rather than a real problem, and it is feasible for farmers to self-finance the use of high-yielding seeds using their own marketable noncommercial liquid assets like livestock and chickens. The results further indicate however, that smallholder sunflower farmers are lacking adequate knowledge of the value of their liquid assets and of the opportunity cost or benefit of taking a credit/loan to finance the use of high-yielding seeds. The implications of these findings is that educating and sensitizing farmers about their potential resources, financial base, and the real cost of credit may influence their choice for self-financing and borrowing options as a way to improve their productivity.
Acute Leukemia
Authors: Larson Richard A. , Walter Roland B
Published: July 2021

The acute leukemias are malignant clonal disorders characterized by aberrant differentiation and proliferation of transformed hematopoietic progenitor cells. These cells accumulate within the bone marrow and lead to suppression of the production of normal blood cells, with resulting symptoms from varying degrees of anemia, neutropenia, and thrombocytopenia or from infiltration into tissues. They are currently classified by their presumed cell of origin, although the field is moving rapidly to genetic subclassification. This review covers epidemiology; etiology; classiﬁcation of leukemia by morphology, immunophenotyping, and cytogenetic/molecular abnormalities; cytogenetics of acute leukemia; general principles of therapy; acute myeloid leukemia; acute lymphoblastic leukemia; and future possibilities. The figure shows the incidence of acute leukemias in the United States. Tables list World Health Organization (WHO) classification of acute myeloid leukemia and related neoplasms, expression of cell surface and cytoplasmic markers for the diagnosis of acute myeloid leukemia and mixed-phenotype acute leukemia, WHO classification of acute lymphoblastic leukemia, WHO classification of acute leukemias of ambiguous lineage, WHO classification of myelodysplastic syndromes, European LeukemiaNet cytogenetic and molecular genetic subsets in acute myeloid leukemia with prognostic importance, cytogenetic and molecular subtypes of acute lymphoblastic leukemia, terminology used in leukemia treatment, and treatment outcome for adults with acute leukemia.
This review contains 2 figures, 15 tables, and 119 references.
Keywords: Acute leukemia, acute myeloid leukemia, acute lymphoblastic leukemia, cancer, cytogenetics, chromosomal abnormality
To Eat or Not to Eat-An Inflammatory Issue
Authors: R Macciochi Jenna
Published: July 2021

Comprised of a rich and complex microbial ecosystem, the human intestinal tract is both an immunological organ and supplier of the body’s energy demand and nutrient requirements. This intestinal microbiota provides a large reservoir of bacterial lipopolysaccharide, (known also as endotoxin) that has an immediate stimulatory action on the innate immune system. The gut has evolved mechanisms to detoxify endotoxin and neutralise its potential inflammatory properties. However, this potent inflammatory molecule is transiently detectable in the circulation of healthy individuals following ingestion of food by virtue of a transient gut epithelial permeability arising from the digestive process itself. This acute post-prandial inflammation is somewhat dependent on meal composition with energy rich meals dense in saturated fat and low in fibre and polyphenols exacerbating the process. Chronic exposure to circulating endotoxin by this mechanism has been associated with a dysregulated cardiometabolic phenotype and risk of cardiovascular disease. Spending the majority of wake time in the post-prandial state therefore may contribute to the pathogenesis of these diseases. In this review, I present an overview of the mechanisms by which post-prandial inflammatory events and raise the possibility of modulating meal frequency as a dietary tool to, at least in part, ameliorate the detrimental outcomes of endotoxemia.
Discovering Novel Biomarkers for Pulmonary Hypertension
Authors: Patel Nadiya
Published: July 2021

Groundbreaking research into a new biomarker that can indicate cardiac damage and mortality in pulmonary hypertension patients has been identified in a recent study by Tzouvelekis, et al. on ‘S100A12.
It is Disturbing, in Spite of the Existence of Appropriate Legislation, Illegal Distribution of Medicines
Authors: Mustafa Omer Abdeen
Published: July 2021

The strategy of price liberalisation and privatisation had been implemented in Sudan over the last decade, and has had a positive result on government deficit. The investment law approved recently has good statements and rules on the above strategy in particular to pharmacy regulations. Under the pressure of the new privatisation policy, the government introduced radical changes in the pharmacy regulations. To improve the effectiveness of the public pharmacy, resources should be switched towards areas of need, reducing inequalities and promoting better health conditions. Medicines are financed either through cost sharing or full private. The role of the private services is significant. A review of reform of financing medicines in Sudan is given in this study. Also, it highlights the current drug supply system in the public sector, which is currently responsibility of the Central Medical Supplies Public Corporation (CMS). In Sudan, the researchers did not identify any rigorous evaluations or quantitative studies about the impact of drug regulations on the quality of medicines and how to protect public health against counterfeit or low quality medicines, although it is practically possible. However, the regulations must be continually evaluated to ensure the public health is protected against by marketing high quality medicines rather than commercial interests, and the drug companies are held accountable for their conduct.
Method of Reconstruction the Intact Surface for Surgical Accesses
Authors: Ismail Saied Husham Farouk
Published: July 2021

The aim of this work lies in designing software used for preoperative planning of the surgical access risk. In order to obtain a realistic and useful simulation we focused our study on the physical modeling of the brain targeting and on the maneuvers of the surgical instruments. A new method of intact surface construction, which will assist in accurate neurosurgical planning, was discussed. Moreover, the three-dimensional model and its visualization were described. This visualization method allows of combining the calculated data about the surgical intervention risks with the geometrical data describing patient's head. Therefore, this methodology will help to build an intelligent system that has the ability of selection the best approach of surgical intervention access. The current technique is based on geometrical synthetic object creation, this object “in next stages of the surgical planning approach” would be applied directly to the data describing the risks of surgical access, and this in turn will allow estimating the real risk value of the surgical access. The advantage of this method is that the creation of the object is based on surgical access approach. The best surgical access is based on finding the smallest distance of surgical intervention toward the target, taking into the account the reduction of brain tissue damage. The method of the intact vertex can significantly reduce the amount of memory overloading, also a method of filtration used to extract artifacts resulting in unreal vertices, caused in rendering errors and memory overloading, was used. Also, using data describing the correlation between the object vertices allows arifacts filtration without any need for additional transformations. All that improves the rendering procedure and the accuracy of the surgical intervention by 30%.
Is there any Relation of Normal Body Temperature with Stress Eating?
Authors: Naeem Qureshi Hira
Published: July 2021

The relation of normal body temperature with stress eating was aim of present research. 125 subjects took part in present research, where their normal body temperature measured. Thermometer is widely used to measure body temperature. The normal temperature of body is in between 36.5–37.5°C (97.7–99.5°F). The overeating during stress and tension is called stress tension. The unhealthy and junk foods are also connected with stress eating. The 125 students take part in this study. They measured their body temperature by thermometer and check that there is any relation of temperature with stress eating. This was resulted from current study that normal body temperature has no effect on stress eating.
Pattern of Medication Prescribing and Factors Associated with Meeting of Target Blood Pressure among Persons with Hypertension in Federal Police Referral Hospital, Ethiopia
Authors: Shimels Tariku
Published: July 2021

Introduction: Hypertension is one of the highly growing chronic health challenges worldwide causing a significant number of deaths and cardiovascular complications. The prevalence of the condition in Ethiopia was estimated to be 19.5% with an urban and rural subgroup proportion of 25.7% and 14.7% respectively. This study was conducted to assess the pattern of prescribing antihypertensive medications and factors associated with BP target meeting among persons with hypertension in Federal Police Referral Hospital. Method: An institution based cross sectional study was conducted from 15th October 2016 to 15th January 2017. A systematic random sampling technique was employed in selecting the study participants. Data was collected using a semi-structured interview of study participants and visiting medication records. SPSS version 20 was used for data entry and analysis. Results: Of the 330 subjects required to be included in the study, 318 (96.4%) fulfilled the inclusion criteria and were considered for further analysis. Diuretics were the top prescribed class of antihypertensive agents accounted by 201(63.2%) of the subjects. Hydrochlorothiazide, a thiazide diuretic, was the most frequent. Next highly utilized classes of drugs included; calcium channel blockers among 172 (54.1%) subjects followed by angiotensin converting enzyme inhibitors prescribed for 153 (48.1%) participants. Target meeting for the systolic and diastolic blood pressure accounted for 142 (44.7%) and 140(44%) of the study subjects respectively. Overall target meeting of the two variables was attained by 103(32.4%) of the participants. Conclusion: Diuretics were the class of drugs most frequently prescribed succeeded by CCBs and ACEIs. The result of this study has also shown that overall BP target meeting among the subjects was suboptimal. Multivariate binary logistic regression has shown that gender, duration of therapy and dietary adherence were associated with BP target meeting.
Immobilization of Heparin on Bacterial Nanocellulose Hydrogels Induces Tubulogenesis of Human Endothelial Cells
Authors: M Dos Reis Emily
Published: July 2021

Models that mimic the angiogenesis initial processes, as adhesion, migration, proliferation and tubulogenesis, are extremely valuable for investigating the action of new anti-cancer drugs. There still is a need for an angiogenesis model that reflects in vivo environment. To address this challenge, we developed a 3D matrix well-defined based on covalently immobilization of heparin (HEP) on bacterial nanocellulose (BNC) hydrogels. Successful immobilization was confirmed by qualitative and quantification analysis. Human umbilical vein endothelial cells (HUVECs) were seeded on bottom and top surfaces of BNC and BNC-HEP hydrogels and cells behavior were analyzed. The bottom surfaces of BNC-HEP hydrogels were able to support cell adhesion and promote proliferation and tubulogenesis formation. Results here presented indicate that the tubulogenesis process could be controlled by physico-chemical properties of the developed hydrogel. The interaction between the bioactive molecule, heparin, and the particular microstructure of BNC induced tubulogenenic behavior of HUVECs in vitro.
Flexible Endoscopy and Cervical Dysplasia Grade 1 and 2
Authors: Samir Anter Salwa
Published: July 2021

Cervical intraepithelial neoplastic grads1 were studied by flexible endoscopy obtaining five images: First image obtaining using white light the second and third image obtaining by blue, green narrow band image respectively by the special technique of endoscopy the fourth image was obtaining after that acetic acid was applied lastly, the iodine stain is applied and the fifth image was recorded after end of examination the five image were recorded and reviewed to be studied in correlation with cytology and histopathology results to be obtaining accurate diagnosis for CIN1
Apple Fruit as a Source of Health Beneficial Compounds
Authors: AK Sabaz
Published: July 2021

Fruits are well known for their high value in human health. Epidemiological studies indicate that consumption of fruits, vegetables and their products are inversely related to carcinogenesis, coronary heart disease, mortality, and aging processes.
Lovastatin as a Treatment of Cardiovascular and Neurological Disorders
Authors: Tokay Tursonjan
Published: July 2021

There is evidence that statins which are mainly used in treatments of dyslipidemia can be used for attenuating symptoms of cardiovascular and neurodegenerative diseases. Lovastatin and other statins are known to function through inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase which is involved in the majority processes such as cell differentiation, proliferation and migration. Recently it was revealed that lovastatin is effective in the reducing total and low-density-lipoprotein cholesterol, lowering the risks of post-surgical complications and mitigation of anticancer drugs’ side effects. Moreover, there are other combinations with other drugs to treat cardiovascular diseases. In addition, antiinflammatory and immunomodulatory effects of lovastatin diminish neurological disorders such as multiple sclerosis (MS). Especially, combination treatment of lovastatin and rolipram in suboptimal doses is considered to be the most promising approach for protecting neuronal axons from demyelination and promoting neuro repair in MS. Although lovastatin demonstrates promising option for treatment of cardiovascular and neurological diseases, more clinical trials and studies in vivo and in vitro are required.
Bacteriological Quality of Some Local Herbal Drugs Sold In Port Harcourt, Nigeria and Antibacterial Susceptibility of Isolates Compared with Clinical Isolates
Authors: Smart Enoch Amala
Published: July 2021

The world is witnessing an unprecedented rise in the use of herbal medicines. In Nigeria some individuals solely believe in the curative ability of local herbal drugs for the treatment of different forms of ailment. Most local herbal drugs are advertized to cure more than an aliment such as infections and hepatitis, diabetes and gastroenteritis, malaria, general body pain and weakness etc. The preparation and packaging of these local herbal medications are not carried out under appropriate hygienic conditions and they could be prone to contamination by potential pathogenic bacteria. Aim: The aim of this study was to determine the bacteriological quality of some local herbal drugs marketed in some parts of Port Harcourt Rivers State Nigeria and their antimicrobial activity compared to some orthodox antimicrobial agents. Materials and Methods: Ten (10) different local herbal drugs were purchased from hawkers, examined for bacteriological quality and antibacterial activities. Each of the sample for bacteriological examination were diluted serially in sterile peptone water by pipeting 1mL of the neat to 9ml of sterile peptone water in a test tube and subsequently diluted to 105 and 0.01mL of the last dilution 105 were cultured on Nutrient and MacConkey agar plates. Susceptibility testing were carried out with the isolated bacteria. The susceptibility was compared with that of already identified clinical isolates of E. coli and S. aureus. Results: The results obtained showed E. coli (69.9%), S. aureus (18.9%), Klebsiella sp. (3.7%) and Bacillus sp. (7.5%) respectively. Antimicrobial susceptibility testing of the isolated bacteria from the local herbal drugs were 100% resistant to the orthodox drugs tested against them, whereas the clinical isolates tested were 50% susceptible to the orthodox drugs. The bacteria isolated from herbal drugs and the isolates from clinical specimens were 100% resistant to the local herbal drugs. Conclusion: The bacteriological qualities of the local herbal drugs marketed in some parts of Port Harcourt were poor due to improper hygiene during processing and packaging. Bacterial isolates from the local herbal drugs were resistant to the local herbal drugs and the orthodox drugs. Contaminated local herbal drugs might serve as means of transmitting infections and medium for exchanging resistant genes by the contaminating bacteria. The antibacterial property of herbal drugs may have been altered by the activities of bacteria
ELF1-Like Protein of Physarum Polycephalum ELF1 (PELF1) Act as a DNA Binding Protein, P14-3-3 Interacted Protein and Regulates DNA Structure
Authors: Shide Liu
Published: July 2021

The function of transcription extension factor 1 (elf1) protein was mainly studied by Saccharomyces cerevisiae, but it was rarely reported in low eukaryotes. In addition, the role of Physarum ELF1 (PELF1) and PELF1/Physarum 14-3-3 (P14-3-3) protein interaction is poorly understood. Q-PCR analysis of the PELF1 mRNA levels indicates that it involved DNA structure formation. Further, confirmed that the DNA binding site of PELF1 is located within 1 to 22 amino acids from the N-terminus. The site of the interaction between PELF1 and P14-3-3 is located on the 40-RDAGI-44 aa peptide at the corner of the βA→βB of the C4 zinc finger domain. Key peptides and amino acids affecting PELF1 binds to DNA. Electrophoretic mobility shift analysis (EMSA) results showed that PELF is faster than P14-3-3/PELF1 complex when they binding to PardC. Atomic force microscopy (AFM) showed that both PELF1/DNA complex and P14-3-3/PELF1/DNA complex aggregated, but P14-3-3/PELF1/DNA complex aggregated most. ITC (Isothermal Titration Calorimetry) showed that P14-3-3/PELF1 complex binds PardC DNA 10 times higher than PELF1 binds to PardC DNA. Finally, our data not only represent the first report of PELF1 regulation of DNA structure formation, but also enhance our understanding of PELF1 as a DNA binding protein and PELF1/P14-3-3 interaction.
Invitro Impact of Diallyl Disulphide (Dads) on the Biochemical Components of the Cell Envelope of Staphylococcus Aureus Atcc 25293
Authors: Fatima Farheen
Published: July 2021

Diallyl Disulphide (DADS) is a phytochemical found in the plants of the genus Allium. It is the principal organosulphuric component of distilled garlic oil. Many medicinal benefits like antimicrobial, antiviral and insecticidal are attributed this compound. However the biochemical explanation for such an action remains unexplored. This current study strives to explore the explanation for antimicrobial activity of the compound using the most common skin inhabitant Gram positive bacteria, commonly causing nosocomial infections- Staphylococcus aureus. The Minimum Inhibition Concentration (MIC), Minimum Bactericidal (MBC) Concentration of DADS, its effect on growth curve and time kill curve of S. aureus has been established. In the current study S. aureus was cultured in the broth containing 1/8 MIC of DADS. The staphylococcal cells were harvested; biochemical components were extracted and quantitated using appropriate biochemical analytic tests. The biochemical components focused on were of those abundantly present and those that contribute to the materialization of the staphylococcal cell envelope total lipids, total lipid phosphorous and total carbohydrates. The biochemical component extracts of S. aureus tested revealed significant reduction in the total lipids (70%), total lipids phosphorous (50%) and total carbohydrates (34%). This reduction in the components may be attributed to the hypolipidemic and hypoglycemic properties of DADS and could further lead to changes in the anabolic processes. Since the cell envelope of the bacterial cell is primarily made up of lipids, phospholipids and peptidoglycan (a carbohydrate polymer). The evident reductions in the studied components indicate reflective impact of DADS on the cell envelope of S. aureus. This study can be extrapolated in innovation of a new phytochemical-antibiotic against the life threatening multidrug resistant human pathogens
Management Skill to Successful Make in an Extra-Marital Affair:Rare Chance to Meet Fact File Study of Transformed in Pharmacy Colleges in Formerly Pune University
Authors: Hajare Rahul
Published: July 2021

A woman who sleeps with a man she just met signals that she has low self-esteem or that she is actually only using him for sex.
β-type Ti Alloys for Biomedical Applications
Authors: Yamanoglu Ridvan
Published: July 2021

In the world market, medical products emerge as a sector that directly concerns people’s life quality and related activities. The medical product industry continues to grow rapidly in the world, especially in developed countries in line with the advances in technology, along with the elderly population and welfare level. In this context, biomedical implants constitute an important branch of the medical product industry. Among the materials preferred for implant production, the metallic biomaterials are very popular due to their superior mechanical properties. Ti and Ti alloys, among the metallic biomaterials, draw more attention considerably compared to stainless steel and Co-Cr alloys due to their characteristic features such as high specific strength and superior corrosion resistance, low density and low modulus of elasticity. Although the elastic modulus of titanium and its alloys is low compared to the other metallic biomaterials, it remains higher than bone. β-type Ti alloys have been developed to prevent the stress shielding effect caused by the elastic modulus mismatch and sterilization of the biomaterials used in the body from toxic alloy elements. In this article, the effect of the use of β-type Ti alloys, which are extremely prospective materials and open to development, in the body on host organisms, and the efficiency of the developed alloys have been investigated.
Promising Drug Design Strategies: Intrinsically Disordered Proteins
Authors: C Michaux
Published: July 2021

In contrast to the classical paradigm “one sequence - one structure - one function” that a given protein sequence corresponds to a well-defined three-dimensional (3D) structure and an associated function, it was discovered in the 1990s that an increasing number of proteins can be functional in the absence of a stable 3D-structure.
Evaluation of Stress Biomakers (Cytokines) in Presence of Unpredictable Chronic Stress (UCS) in Sprague Dawley Rats after Treatment with the Biofield Energy Treated Novel Proprietary Test Formulation
Authors: Jana Snehasis
Published: July 2021

Unpredictable chronic stress (UCS) model was used to evaluate the effect of Consciousness Energy Healing Treatment (the Trivedi Effect®) on a novel test formulation in male Sprague Dawley (SD) rats for the estimation of serum cytokines such as TNF-Alpha, IFN-Gamma, IL-6, and IL-2, along with C-reactive protein (CRP) using ELISA assay. A test formulation was formulated including minerals (calcium, copper, iron, magnesium, selenium, and zinc), vitamins (ascorbic acid, alpha tocopherol, cholecalciferol, cyanocobalamin, and pyridoxine HCl), cannabidiol isolate, Panax ginseng extract, and β-carotene. The constituents of the test formulation were divided into two parts; one part of each ingredient was defined as the untreated test formulation, while the other parts and three groups of animal received Biofield Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Mr. Mahendra Kumar Trivedi. The cytokines estimation results showed that the level of IL-2 was reduced by 14.2% in Biofield Energy Treatment per se to the rats (G6) group as compared with the disease control group (G2). TNF-α level in serum was decreased by 11% in the G6 group as compared with the G2 group. IL-6 level in serum was decreased by 21.7%, 30.8%, 16.3%, 10.1%, and 13.4% in the G5, G6, G7, G8, and G9 groups, respectively as compared with the G2. However, IFN-γ level was decreased by 18.3% and 11% in the G6 and G9 groups, respectively as compared with the G4. Similarly, CRP level was significantly decreased by 25.8%, 15.2%, and 14.6% in the G5, G6, and G7 groups respectively, as compared with the G4. All-inclusive, Mr. Trivedi’s Biofield Energy Healing Treatment/Blessing per se along with other preventive treatment groups showed a significant impact on various inflammatory disorders (gout, inflammatory arthritis myositis, rheumatoid arthritis, scleroderma, etc.). Therefore, the outcomes could be slowdown the stress-related disease progression and its complications/symptoms in the preventive maintenance groups (viz. G6, G7, G8, and G9).
Benign Prostatic Hyperplasia in African American Men Merits Greater Consideration in Academic Medicine
Authors: Wiedemer MS Joseph
Published: July 2021

Benign Prostatic Hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland, which is highly prevalent in aging men. This process of benign prostate enlargement is known to occur more rapidly in African American men, which has resulted in a disproportionately increased prevalence relative to the general population. In the United States, the cause of this disproportionately increased risk in African Americans is believed to be due to both genetic factors as well as a complex myriad of variables related to health disparities. Despite a robust increase in research related to prostate cancer in African American men, the issue of BPH/LUTS in the African American community deserves equally increased attention in academic medicine. The purpose of this article is to provide a brief review of the medical literature on BPH/LUTS in the African American community to highlight unknown components of the disease and to demonstrate the need for more equitable urologic healthcare.
An Assessment of Teachers' Performance Management System: The Case of Saudi Ministry of Education
Authors:   , Alshaikhi Nada
Published: July 2021

Performance management system (PMS) is now seen as a strategic initiative to enhance individuals’ performance and consequently that of the organisation. The aims of performance management (PM) are to create a shared vision of the goals and objectives of an organisation and to help individuals to understand and recognise their duties and responsibilities as contributing to managing and improving both themselves and their organisation. The main aim of this study is to examine the effectiveness of PMS of teachers in the Saudi Ministry of Education. In addition, the study analyses the ability of management departments within the Saudi Ministry of Education to make administrative decisions based on PM outcomes that may affect teachers’ careers. The current research aims to identify the shortcomings of the PMS for teachers in order to determine how teaching quality may be developed and improved. The study also aims to examine teachers’ perspectives of the determinants of teachers’ PM satisfaction in the Saudi Ministry of Education. This is accomplished through a self-administered questionnaire survey of teachers, designed to measure teachers’ opinions of the PMS. A total of 502 teachers completed the survey. Statistical Package for Social Science (SPSS) and Analysis of Moment Structure (AMOS) were used to analysis the data. The findings of the study demonstrate that teachers’ perceptions regarding their PMS are generally oriented towards dissatisfaction. The results show that this dissatisfaction arises from the problems relating to the PM process itself. Additionally, the PMS for Saudi teachers does not capture the necessary information for managers to make informed decisions and policies in relation to the teachers. Moreover, many PMS-related problems such lack of training of head teachers for conducting PMS along with teachers’ beliefs about bias errors existing in PMS caused teachers’ dissatisfaction. The findings revealed ineffectiveness in PMS and suggested that moving towards effectiveness requires setting goals and objectives, providing ongoing feedback, conducting accurate performance appraisal, fairness of performance appraisal, pay for performance, meeting training and development needs, promotion decisions, management commitment to the PM process, the involvement of teachers in developing the PMS and their understanding of the purpose of the PMS. Therefore, this study has proposed recommendations to overcome the shortcomings of the existing system and to enhance teachers’ satisfaction with their PM.
The educational environment for improving students' self-study: best european practices
Authors: Murzina Olena , Lisnevska Alina , Masytska Tetiana , Melnyk Iryna , Levchuk Tereza , Sokolova Viktoriia
Published: July 2021

The aim of the article is to investigate the influence of educational environment on students' self-study, which can deepen the understanding of pedagogical design of mixed education. During the study and assessment of informational sources the economical and statistical, abstract-logical, economical and mathematical research methods, methods of factor and correlation analysis were used. The obtained indicators, on the one hand, are a positive result and indicate the effectiveness of the model for the use of the educational environment Moodle to improve students' self-study, and, on the other hand, point to the need for management actions aimed at raising the level of organization and implementation of the educational process. The implementation of best practices of European countries, namely the educational environment Moodle, allows the organization of active cognitive self-study activities of students, improve their performance, increase the amount of information provided in the classroom, increase motivation for learning.
Labor training in design and technological activities of students
Authors: Sribna Yuliia , Borysova Tetiana , Savenko Ihor , Kaliazin Yurii , Tytarenko Valerii , Svyrydiuk Nataliia
Published: July 2021

The aim of this article is to establish the effectiveness of labor training of students by using modern pedagogical and technological systems; determination of strong interest in implementation of project activities, as well as determination of teachers' attitude to implementation of labor training based on project-technological activities. The main method in the article is the experiment method; also, the questionnaire and observation methods were used. The result of the research is to establish the necessity of introducing design-technological activities into the process of labor education as a form of motivation and formation of strong interest of schoolchildren. It was found that project-technological activity is positively perceived by teachers in the field of labor education and is considered by them as effective and corrosive. It is stated that the labor lessons form a set of knowledge and skills in the technological sphere, develop a strong interest in creative work, and create conditions for the realization of intellectual abilities.
Physical activity of the older population as a factor of active longevity
Authors: Bronnikova Evgeniya M. , Kulyamina Olga S. , Vinogradova Marina V. , Shatsky Alexander А. , Ponyashova Anastasia S.
Published: July 2021

The article presents the results of a study based on the data of an all-Russian sociological survey of the population. 2444 people over 60 years old were interviewed throughout Russia. Based on the obtained data, an assessment was made of the relationship between physical activity and self-assessment of the level of health, the duration of the illness per year, and the conduct of a healthy lifestyle. It was revealed that at a statistically significant level, elderly people who go in for sports assess themselves as healthier than those who do not play sports and lead a less active lifestyle, it was revealed that healthier and less often sick elderly people are more active in sports.
PEMBERDAYAAN EKONOMI PRODUKTIF PADA SANTRI PESANTREN AT-TAQWA, KAB. SUMEDANG MELALUI BUDIDAYA MAGOT LALAT TENTARA HITAM (Hermetia illucens) SEBAGAI AGEN BIOKONVERSI LIMBAH ORGANIK SEKALIGUS SUMBER PAKAN TERNAK TINGGI PROTEIN
Authors: Supriatna Ateng , Kulsum Yuni , Cahyanto Tri , Darniwa Adisty Virakawugi , Julita Ucu , Fadillah Afriansyah , Adawiyah Ayuni
Published: July 2021

Permasalahan kemiskinan dan lingkungan masih menjadi perhatian utama pemerintah pusat maupun daerah. Program yang dilakukan oleh pemerintah yaitu dengan mengembangkan program pemberdayaan sumber daya manusia terutama yang berusia muda. Melalui program pengabdian masyarakat berbasis pesantren diharapkan dapat meningkatkan peran santri pondok pesantren At-Taqwa, Kabupaten Sumedang Jawa Barat dalam pemberdayaan ekonomi kreatif sehingga mampu meningkatkan kesejahteraan santri dan masyakat sekitar pesantren. Model pendekatan yang diterapkan dalam pelaksanaan pemberdayaan ini adalah pendekatan partisipatoris sekaligus pemberdayaan masyarakat berbasis asset atau resources. Budidaya magot lalat tentara hitam (hermetia illucens) sebagai agen biokonversi limbah organik sekaligus sumber pakan ternak tinggi protein ini merupakan program yang berhasil menginisiasi perkembangan ekonomi kreatif di kalangan santri At Taqwa.
PENERAPAN TEKNOLOGI WINDROW COMPOSTING BAGI MASYARAKAT SEKITAR TPA MUARA FAJAR PEKANBARU
Authors: Zahrina Ida , Yenie Elvi
Published: July 2021

Volume sampah organik yang cukup besar di TPA Muara Fajar dapat dimanfaatkan oleh warga sekitarnya dengan mengolahnya menjadi kompos. Selain dapat memperpanjang umur TPA, kegiatan pengomposan ini juga dapat meningkatkan perekonomian masyarakat. Oleh karena, perlu adanya kegiatan pengabdian kepada masyarakat sekitar TPA Muara Fajar agar memiliki ketrampilan dalam mengolah sampah organik menjadi kompos dengan teknologi windrow composting. Teknologi ini cocok diterapkan bagi warga sekitar TPA Muara Fajar karena dapat diaplikasikan untuk semua jenis sampah organik, loading capacity yang besar, serta menghasilkan kompos dengan kualitas yang baik. Kegiatan ini diikuti oleh warga RT 01 RW 03 Kelurahan Muara Fajar, Pekanbaru melalui sosialisasi, penyuluhan, pelatihan serta evaluasi. Dari kegiatan ini, masyarakat telah mampu memproduksi kompos dari sampah organik. Namun masih perlu kegiatan pengabdian lanjutan untuk membentuk unit usaha kompos di masyarakat.
Mini Review : Sedem System as a Tool to Characterize Excipients in Solid Dosage Form
Authors: Sopyan Iyan , Khairunisa Rizka Guntina
Published: July 2021

SeDem System is a new system that can be applied in solid dosage form preformulation studies of medicines. It have parameters to evaluates critical quality attributes of materials that have an impact on final drug product’s quality. SeDeM studies could be used as a method for identifying the best excipient and calculating the maximum amount of excipient required for formulation. SeDeM method can , providing formulation with the lowest amount of excipients as it combines the Active Pharmaceutical Ingredients (API) with only one excipient and the standard formula of lubricants, thus avoiding the used of unnecessary excipients, such as diluents, binders and agglutinants. The information given by the SeDeM system contributes to a quality by drug design development.Keywords: SeDeM System, Excipients
PENGARUH KEPEMIMPINAN, MOTIVASI DAN KOMPENSASI TERHADAP KEPUASAN KERJA KARYAWAN DI PERUSAHAAN PT. MITRA KARUNIA INDAH
Authors: Novialni Riska , Pragiwani Meita
Published: July 2021

Penelitian ini bertujuan untuk mengetahui hubungan antara Kepemimpinan, motivasi dan kompensasi terhadap kepusasan dari kerja karyawan di PT. Mitra Karunia Indah.Populasi penelitian ini adalah karyawan yang bekerja pada kantor pusat (head office) PT. Mitra Karunia Indah dengan menggunakan google from sebagai media kuesioner. Metode pengambilan sampel menggunakan teknik Slovin dengan jumlah sampel 124 responden. Strategi yang digunakan dalam penelitian ini adalah strategi kuantitatif yang diukur dengan perhitungan Koefisien Determinasi (R2) parsial serta pengujian hipotesis uji t dengan SPSS 25.0 .Hasil penelitian menunjukan bahwa, (1) Kepemimpinan secara parsial berpengaruh signifikan terhadap kepuasan kerja karyawan, (2) Motivasi secara parsial berpengaruh signifikan terhadap kepuasan kerja karyawan, (3) Kompensasi secara parsial berpengaruh signifikan terhadap Kepuasan Kerja This study aims to determine the relationship between leadership, motivation and compensation for employee job satisfaction at PT. Mitra Karunia Indah.The study population was employees who worked at the head office of PT. Mitra Karunia Indah using Google from as a media questionnaire. The sampling method using Slovin technique with a sample of 124 respondents. The strategy used in this study is a quantitative strategy that is measured by calculating the partial determination coefficient (R2) and testing the t-test hypothesis with SPSS 25.0.The results showed that, (1) Leadership partially had a significant effect on employee job satisfaction, (2) Motivation partially had a significant effect on employee job satisfaction, (3) Compensation partially had a significant effect on Job Satisfaction.
FAKTOR-FAKTOR YANG MEMPENGARUHI KUALITAS AUDIT INTERNAL KEMENTERIAN AGRARIA DAN TATA RUANG/BPN
Authors: Luthfi Muhammad , Myrna Rita , Candradewini Candradewini
Published: July 2021

Salah satu cara dalam mencapai tata kelola pemerintahan yang baik, akuntabel dan dapat dipertanggungjawabkan, adalah melalui audit internal yang baik. Dari berbagai faktor pengaruh terhadap kualitas hasil audit, penelitian ini bertujuan untuk menganalisis seberapa besar pengaruh kompetensi dan independensi auditor internal secara parsial dan simultan terhadap kualitas audit internal di Kementerian Agraria dan Tata Ruang/BPN (ATR/BPN). Metode penelitian yang digunakan adalah analitik kuantitatif dengan desain potong lintang. Metode analisis yang digunakan adalah Partial Least Square – Structural Equation Modelling (PLS-SEM). Dari pengujian terhadap model penelitian, didapatkan bahwa kompetensi dan independensi secara parsial memiliki pengaruh positif dan signifikan terhadap kualitas audit; dan secara simultan, kompetensi dan independensi memiliki pengaruh positif dan signifikan sebesar 53,7%. Hasil penelitian menunjukkan bahwa kompetensi dan independensi merupakan faktor yang mempengaruhi kualitas audit internal di Kementerian ATR/BPN. Maka diharapkan Kementerian ATR/BPN dapat memperhatikan kedua hal tersebut agar kualitas audit dapat dipertahankan bahkan ditingkatkan lebih baik lagi. Penelitian lebih lanjut dibutuhkan dengan metode penelitian yang berbeda serta melibatkan variabel dan jumlah sampel yang lebih banyak.
PERAN RASIO KEUANGAN DAN KINERJA KEUANGAN PERUSAHAAN
Authors: Putra Bintang Ramadani , Alexandri Moch. Benny
Published: July 2021

ABSTRAK Penelitian ini bertujuan untuk (1) bagaimana manfaat dari analisis rasio keuangan?(2) bagaimana rasio keuangan dapat memprediksi peringkat obligasi (3) bagaimana rasio keuangan dapat memprediksi distress pada perbankan (4) bagaimana rasio keuangan dapat memprediksi perubahan laba rugi (5) bagaimana rasio keuangan dapat menunjukan pengaruh merger terhadap kinerja keuangan. Hasil penelitian Seperangkat rasio keuangan (leverage, likuiditas, solvabilitas, profitabilitas dan produktivitas) mempunyai kemampuan membentuk model untuk memprediksi peringkat obligasi. Suatu rasio tidak memiliki arti jika berdiri sendiri, melainkan harus dibandingkan dengan rasio keuangan pada periode sebelumnya sehingga dapat mengetahui kecenderungan selama periode tertentu. Selain dibandingkan dengan rasio periode sebelumnya dapat juga dibandingkan dengan rasio keuangan dari perusahaan lain dengan jenis perusahaan yang sama.Kata Kunci : Rasio Keuangan, Analisis, Distress, Laba Rugi ABSTRACT This study aims to (1) how are the benefits of financial ratio analysis? (2) how financial ratios can predict bond ratings (3) how can financial ratios predict distress in banking (4) how can financial ratios predict changes in income (5) how financial ratios can show the effect of the merger on financial performance. Research Results A set of financial ratios (leverage, liquidity, solvency, profitability and productivity) has the ability to form models to predict bond ratings. A ratio has no meaning if it stands alone, but must be compared with financial ratios in the previous period so that we can find out trends during a certain period. Apart from being compared with the ratios of the previous period, it can also be compared with the financial ratios of other companies with the same type of company. Keywords: Financial Ratios, Analysis, Distress, Profit and Loss
ANALISIS METODE ECONOMIC ORDER QUANTITY (EOQ) DAN ANALISIS KLASIFIKASI ABC SERTA ANALISIS VITAL, ESENSIAL DAN NON ESENSIAL (VEN) TERHADAP PERSEDIAAN OBAT
Authors: Alexandri Moch. Benny , Pragiwani Meita , Inayah Inayah
Published: July 2021

Penelitian ini memiliki tujuan (1) Bagaimana sistem penentuan persedian obat di Klinik-Apotek Dharma Tangerang., (2) Bagaimana analisis metode economic order quantity (EOQ) terhadap penentuan persediaan obat di Klinik Apotek Dharma Tangerang. (3) Bagaimana analisis klasifikasi ABC terhadap penentuan  persediaan obat pada Klinik Apotek Dharma Tangerang. (4) Bagaimana metode analisis vital, esensial dan non esensial (VEN) terhadap penentuan persediaan obat pada Klinik Apotek Dharma Tangerang. Jenis penelitian ini adalah deskriptif kuantitatif dengan memaparkan bagaimana pengendalian persediaan obat yang diterapkan di Klinik Apotek Dharma Tangerang. Lewat data yang diperoleh akan  dianalisis menggunakan metode economic order quantity (EOQ),  metode analisis klasifikasi ABC dan analisis vital, esensial dan non esensial (VEN).Hasil penelitian ini Pada penggunaan analisis klasifikasi ABC berdasarkan nilai investasi dapat diketahui kelompok A dari golongan obat vital 69,83% dengan volume 17 unit, golongan obat esensial 70,23% dengan volume 13 unit dan golongan non esensial 70,69% dengan volume 6 unit.Kelompok B dari golongan obat vital 20,16% volume 18 unit, golongan obat esensial 19,24% dengan volume 14 unit dan golongan non esensial 17,88% dengan volume 7 unit. Kelompok C golongan vital 10,01% volume 31 unit, esensial 10,53% dengan volume 31 unit dan golongan non esensial 9,48% dengan volume 23 unit. Dengan metode EOQ dalam pengadaan sediaan obat biaya pembelian unit obat untuk golongan obat vital Rp 1.069.223.104 dengan nilai EOQ terendah 1 dan tertinggi 105, untuk golongan obat esensial Rp. 280.472.456 nilai EOQ terendah 1 dan tertinggi 41, dan golongan obat non esensial Rp. 148.042.836  dengan nilai EOQ terendah 1 dan tertinggi 58.
DETERMINANT TAX AVOIDANCE IN BASIC AND CHEMICAL INDUSTRY MANUFACTURING COMPANIES LISTED ON THE IDX
Authors: Hamilah Hamilah , Situmorang Kenny F.
Published: July 2021

Profitability is one factor to attribute the company’s financial condition to tax avoidance. Leverage is a ratio to measure a company’s ability to pay all its liabilities both short-term and long-term. In addition to profitability and leverage, sales growth can also affect tax avoidance activities. By measuring the sales growth of a company can predict how much profit it earns so that the company will tend to practice tax avoidance. The purpose of this research is to build a theory that serves to explain a relationship. The relationship used is a causal relationship that influences variables and other variables. The study uses quantitative research methods with a causal descriptive and associative approach to determine the influence between two or more variables. The test results showed that returns on assets, debt to equity ratio, and sales growth affected the cash effective tax rate.f research
DIGITAL LITERACY COMPETENCES IN IMPROVING THE PROBLEM-SOLVING SKILLS IN FACING THE INDUSTRIAL REVOLUTION 4.0
Authors: Harnani Nining , Amijaya Dodi Tisna , Setiadiwibawa Luthfi
Published: July 2021

This study aims to determine student’s digital literacy competences in improving the problem-solving skills in facing the era of Industrial Revolution 4.0, which is conducted on students at several state and private universities in Bandung. This study is expected to contribute to determining student’s digital literacy competences. The methods used in this study are descriptive and verification methods, in which the data obtained will be turned into numbers, converted into percentages, and then described. The sampling technique used is purposive sampling technique, namely students at colleges and universities, both public and private in Bandung. In this study, the sample used is 300 students. The analytical tool used is regression analysis with the SPSS program. Based on the results of the study, it is found that the digital literacy competences of students in Bandung can be categorized as Good, and the problem-solving skills of students in Bandung can be categorized as Good. The results of regression analysis shown that t-count (10,902) > t-table (1,967). This means that the digital literacy competences have an effect on problem-solving skills, in which every change of 1 (one) unit in the digital literacy competences can increase the problem-solving skills by 720 units. Therefore, it can be concluded that the digital literacy competences significantly influence the problem-solving skills.