bluuebunny/crossref_metadata_2025 huggingface dataset:
Priseljevanje v Slovenijo s področja nekdanjih jugoslovanskih republik v času socializma in njegov odmev v javnost
Authors: Piškurić Jelka
Published: December 2022

Prispevek prikazuje priseljevanje s področja nekdanjih jugoslovanskih republik v Slovenijo v času socializma. Avtorica pri tem poskuša prikazati, kako ga je sprejelo večinsko prebivalstvo. Z večjim pritokom pripadnikov drugih jugoslovanskih narodov, ki so v Sloveniji iskali boljše možnosti za zaslužek in življenje, so se odpirala vprašanja o priseljevanju in zaposlovanju delavcev iz drugih republik. Zadržan odnos Slovencev do priseljencev, na katerega so sprva vplivale zlasti kulturne in jezikovne razlike, se je v 80. letih krepil v luči politične in ekonomske krize, v katero se je poglabljala Jugoslavija.
Preparation and evaluation of polyherbal hand wash
Authors: Mouna A  , Ashok Kumar BS  , Sufiya Sulatana  , Brunda MA  , Bindu MA
Published: December 2022

The main objective is to prepare polyherbal Hand wash formulation by using methanolic extract of Azadirachta indica and Mimosa pudica, Aloe vera, Sodium lauryl sulphate, Glycerine, Methyl paraben, Sandalwood oil and Water. The developed hand wash formulations were subjected for evaluation. Formulated polyherbal hand wash was evaluated by the parameters like: colour, fragrance grittiness, pH, spreadability, foam retention, washability, foam height, viscosity and skin irritation test respectively. All parameters are within the standards.
ANALISIS KEPUASAN PENGGUNA PADA SISTEM APLIKASI PERPAJAKAN PT. ASURANSI SIMAS INSURTECH DI JAKARTA DENGAN METODE TAM
Authors: Sulistyowati Rini , Susilowati Herni
Published: December 2022

PT. Asuransi Simas Insurtech makes a taxation application to assist companies in carrying out taxation documentation both corporate tax documents and for counterparties. This application was created as a means to simplify and shorten the workings of companies and transaction opponents to access their tax documents or data. This study aims to determine whether the taxation application system of PT. Insurance Simas Insurtech can be accepted or not by employees and transaction opponents of PT. Insurance Simas Insurtech. From known problems, measurements are made using the right method. PT. Asuransi Simas Insurtech as the object of research. The tool for conducting this research is to use the Technology Acceptance Model method in the taxation application system at PT. Insurance Simas Insurtech. The relationship between the four factors that influence the acceptance of the taxation application system, namely, the perception of ease, perceived usefulness, user attitude and user interest in receiving the taxation application system. Users really believe that the system is indeed very beneficial and there is ease of use. This factor triggers an increase in the value of the taxation application of PT. Insurance Simas Insurtech for users.
The Impact of Digitalization and Trade Openness on Economic Growth: New Evidence from Richest
Asian Countries
Authors: BAKARI Sayef , WERIEMMI Malek El , MABROUK Mohamed
Published: December 2022

The aim of this investigation is to check the impact of digitalization and trade openness on
economic growth for top ten richest Asian countries. Static Gravity Model and Generalized Method
of Moments Model were estimated. We found that digitalization and trade openness have a
significant positive effect on economic growth. These results prove that trade openness and
digitalization is a source of economic growth for richest Asian countries. Due to the magnitude
of the positive externalities attached to the trade openness and digitalization, in terms of
technology transfer bias, financial capacities, economic policies, human expertise, plenty of
natural resources, large markets size, and spillover effect added to the domestic capacities and
the national investment, the pace of the phenomenal economic performance of the Asian economies
is very well marked.
Improving Micro-, Small and Medium Enterprise’s Access to Start-up Financing in ASEAN
Countries
Authors: MARAN Raluca
Published: December 2022

Lack of access to finance constitutes a major setback to the development of the micro-,
small and medium-sized enterprise (MSME) sector in the countries of the Association of Southeast
Asian Nations (ASEAN). MSMEs are confronted with stringent funding constraints in traditional
lending and capital markets, in particular at the early stages of their activity. Demand and
supply of capital to MSMEs thus entails more complex issues compared to the larger firms. This
paper presents a number of policy actions that have the potential to mitigate the financing
challenges faced by MSMEs in ASEAN at the start-up stage by enhancing the potential of
alternative funding sources such as business angel investment, crowdfunding, venture capital
investment and SME stock markets.
Institutional Quality and Economic Growth in Tanzania
Authors: GIBOGWE Vincent , KUFUOR Karen , NIGO Ayine
Published: December 2022

In this paper, we use the ARDL method to find the Impact of institutional quality on economic growth in Tanzania from 1990 to 2021. The ARDL technique frees variables from residual correlation as all variables are assumed to be endogenous. They distinguish between dependent and explanatory variables in any long-run relationship, identify the co-integrating vectors with multiple co-integrating vectors, and derive the Error Correction Model (ECM) or Error Correction Model (ECM) Vector Error Correction Model (VECM) by integrating short-run adjustments with long-run equilibrium without losing extended-run information. Our results show all adjustment terms in the respective models that have a long-run relationship have correct (negative) signs and are more than one, implying there is convergence in the long run; that is, the models returned to their long-run equilibrium; the rate (or speed) at which this happened ranged between 15% to 106.6% annually. Institutional quality has a significant affirmative (0.047) causal long-run effect on economic growth.© 2022 The Author(s). Published by RITHA Publishing. This article is distributed under the terms of the license CC-BY 4.0., which permits any further distribution in any medium, provided the original work is properly cited.
About Governance of Agricultural Knowledge and Innovation System. The Case of Bulgaria. Part II
Authors: BACHEV Hrabrin
Published: December 2022

This paper is the second part of the attempt to examine the governance, efficiency, and development of the Agricultural Knowledge and Innovation System (AKIS) in Bulgaria. In the years of EU membership, the expenditures for AR&D significantly decreased absolutely and relatively as a share in the total expenditures for R&D, which indicates diminishing importance and deteriorating financial, personnel, and material potential of the agrarian knowledge and innovation sector. The research continues the first part already published in the previous issue with the third point of view related to the governance of agrarian research in Bulgaria is unpacked; forth, the state of the system of education and training of agricultural producers in the country is analysed.© 2022 The Author(s). Published by RITHA Publishing. This article is distributed under the terms of the license CC-BY 4.0., which permits any further distribution in any medium, provided the original work is properly cited.
Prototipe Robot SUMO Otonom dalam Mengenali Object Musuh berbasis Sensor Ultrasonic
Authors: Amal Iskariman Halmahera
Published: December 2022

The current competition is not only done by humans, but has entered into interference from technology, one of which is robotics technology. One of the competitions is the sumo robot competition, the purpose of making this sumo robot is to be able to move independently or autonomously and be able to detect enemies and push enemies out of the arena, so that the functionalities of the robot are similar to sumo wrestlers and after that can be included in the competition. This sumo robot uses an arduino nano microcontroller as the brain of the robot, five ultrasonic sensors and two proximity sensors, in technical terms the assembly begins with the design, assembly, programming and finally testing. Robot testing is done by testing the characteristics of the movement based on sensor input. The result is the robot will react if there is an object with a radius of 75 cm from the robot and the robot also reacts when the floor surface is light colored.
A retrospective analysis of blood culture-negative endocarditis at a tertiary care centre in Switzerland
Authors: Dähler Roman , Brugger Silvio D. , Frank Michelle , Greutmann Matthias , Sromicki Juri , Marques-Maggio Ewerton , Imkamp Frank , Bauernschmitt Robert , Carrel Thierry , Zinkernagel Annelies S. , Hasse Barbara
Published: December 2022

AIMS OF THE STUDY: Numerous studies from different countries have contributed to an improved understanding of blood culture-negative infective endocarditis. However, little is known about its epidemiology and microbiology in Switzerland. We aimed to assess the epidemiology and microbiology of blood culture-negative endocarditis at the University Hospital Zurich, Switzerland. 

METHODS: We screened all patients hospitalised between 1997 and 2020 with possible or definite endocarditis at our institution. Thereof, we identified all cases with blood culture-negative endocarditis and retrospectively retrieved patient characteristics, microbiological, histopathological, radiographic and surgical data from medical records.

RESULTS: Among 861 patients screened, 66 (7.7%) cases of blood culture-negative endocarditis were identified. Thereof, 31 cases could be microbiologically documented or not documented (n = 30), and in five cases a non-infectious aetiology was confirmed. Endocarditis predominantly affected men (77%) and the left heart (79%); predisposing factors were prosthetic valves (42%), congenital heart disease (35%) and prior endocarditis (14%). The most common reasons for negative blood cultures were antibiotic treatment prior to blood culture sampling (35%), fastidious and slow growing microorganisms (30%) and definite non-infective endocarditis (8%). Coxiella burneti i and Bartonella spp. were the most common fastidious bacteria identified. In addition to serology, identification of causative microorganisms was possible by microbiological and/or histopathological analysis of tissue samples, of which polymerase chain reaction testing (PCR) of the 16S ribosomal RNA proved to be most successful.

CONCLUSIONS: The present study provides a detailed analysis of blood culture-negative endocarditis over a time span of more than 20 years in Zurich, Switzerland. Antibiotic treatment prior to blood collection, and fastidious and slow growing organisms were identified as main reasons for sterile blood cultures. Typical culture-negative bacteria were mainly found by PCR and/or culture of tissue samples.
Temporalizações e temporalidades: sobre o tempo no acontecimento do dizer
Authors: Biavati Nadia Dolores Fernandes , Carvalho Gabriele Cristine
Published: December 2022

O presente trabalho apresenta os modos como mobilizamos sentidos sobre o tempo nos acontecimentos de dizeres típicos da pandemia do SARS-COV-2. Destacamos formações, como “novo normal” e “dia D” e “hora H”, que caracterizam o referencial histórico da pandemia, pelo olhar da Semântica da Enunciação. Propomos o foco à temporalidade do dizer a que se refere Guimarães (2002, 2018), uma vez que o acontecimento temporaliza. Nesse ponto, discutimos uma proposta de olhar de separação didática dos sentidos que construímos sobre o tempo, realçando como a temporalidade do dizer acontece e o modo como temporalizações reconstroem e redefinem sentidos, colocando a nossa visão às significações e como elas se (re)moldam, produzindo os acontecimentos do dizer sobre/ na pandemia, uma vez que os sujeitos são tomados pela linguagem na historicidade e constituem o Logos. Desse modo, observamos como os discursos se dão a partir de referenciais, moldando o mundo pela linguagem que ora se delineia nas emergências.
Constructs and Outcomes of Fun in Digital Serious Games: The State of the Art
Authors: Tondorf Diego Fellipe , Hounsell Marcelo da Silva
Published: December 2022

Game design depends not only on understanding the creation process but also the elements that lead the game to be played. Fun, one of these elements, is of important value for the players’ enjoyment as well as their experience with the game, particularly with Serious Games (SG) due to its use as an instrument to serious matters. But there is no consensus on what it is and how to create something fun in SG. This paper performs a systematic literature mapping, to answer which are the constructs and outcomes related to fun. Out of 1062 papers, 62 were selected, 19 of which proved a direct impact of some factors on fun. It was found that the research on fun is increasing but slowly, 13 constructs have been proved to yield fun and 17 outcomes were investigated as a result from fun. Along with this, a Fun Framework was created based on related work. However, it was not possible to perceive a trend as to the rationale or form of evaluation focused on fun. Also, it was found that there is no consensual author regarding the definition of fun. The need for more research and discussion about fun, its causes and consequences became clear, despite the lack of a sound definition.
UNESCO-Weltkulturerbe und postkoloniale Diskurse
Authors: von Schorlemer Sabine
Published: December 2022

Die Abhandlung zielt darauf, innerhalb von facettenreichen postkolonialen Diskursen valide Kritikpunkte, die speziell das Teilgebiet des UNESCO-Weltkulturerbes betreffen, zu identifizieren und in den existierenden völkerrechtlichen und institutionellen Rahmen einzuordnen. Dies geschieht u. a. in Bezug auf die Nominierung und die Verwaltung von Weltkulturerbe im Rahmen der Welterbekonvention (1972), unter spezieller Beachtung der Partizipationsforderungen von unterschiedlichen Gemeinschaften. Auf diese Weise soll ein klareres Bild gewonnen werden, ob normative Schutzlücken und Umsetzungsdefizite – gegebenenfalls auch verdeckte postkoloniale Muster – existieren und, bejahendenfalls, welche Reformschritte seitens der UNESCO zu verzeichnen sind.

Die Autorin, die selbst Inhaberin eines UNESCO-Lehrstuhls ist, verortet dabei Kulturerbe als identitätsprägend und vertritt eine Perspektive, welche das Bewusstsein für den Nexus zwischen Weltkulturerbe, kulturellen Menschenrechten und Nachhaltigkeit schärft.
“From spoiling natives to no work, no food”: Food scarcity and the controversy of food rations during the South African War
Authors: Manaka Mpho
Published: December 2022

Food became scarce during the South African War (1899–1902), which led to large numbers of the population dying from starvation or diseases related to hunger. This was due to certain towns in the country being under siege, while farms and homesteads were burned down. The study on which this article is based, examined three main causes of food shortages during the South African War: the unequal distribution of food rations during the siege of Mafikeng, particularly in the concentration camps; complaints by white communities about the “spoiling of natives”; and the introduction of the “no work, no food” policy. The study further reviewed the use of food during commemorations following the establishment of the so-called relief of Mafeking dinners.
The Effect of Neutrophil to Lymphocyte and Neutrophil to Platelet Ratios on Prognosis in Stroke Patients
Authors: BOZ Pınar Bengi , BOZ Murat , ACAR Dilek , ŞANLI Zeynep Selcan , EVLİCE Ahmet , GİRAY Semih
Published: December 2022

Background: The aim of this study is to determine the correlation of neuroinflammatory response biomarkers neutrophil to lymphocyte ratio (NLR), neutrophil to platelet ratio (NPR) with risk factors, etiology, and prognosis in stroke patients.

Methods: Cases diagnosed with ischemic stroke were recruited in this study. Demographic data, comorbidities, laboratory findings, carotid doppler ultrasonography, NIHSS (National Institutes of Health Stroke Scale) and MRS (modified rankin scale) scores of the cases were documented. Afterwards, the cases were divided into 3 groups (posterior circulation infarct, anterior circulation infarct, and lacunar infarct).

Results: A total of 133 patients, 65 female and 68 males, aged between 24 and 94 were included in this study. At the end of hospitalization, NLR (p=0.001) and NPR (p=0.007) were significantly found high in patients with unfavorable functional outcome (MRS≥3) and those who died compared to NLR (p=0.001) and NPR (p=0.008) in the favorable functional outcome group. The NLR cut-off value for unfavorable functional outcome (95% confidence interval lower limit of area-under-curve of ROC≥0.7) was found to be 4.0.

Conclusion: High NLR and NPR values measured at first admission in patients with acute ischemic stroke are highly associated with unfavorable functional outcome and mortality, and NLR and NPR are important prognostic biomarkers in patients with acute ischemic stroke.
The association between frequent premature atrial contractions and recurrent stroke in a population of ischemic stroke
Authors: GÜNLÜ Serhat , AKTAN Adem
Published: December 2022

Objective: Premature atrial contractions (PACs) are a prevalent cardiac occurrence. Recent research indicates that PACs are linked to atrial fibrillation (AF), ischemic stroke, and mortality. We aimed to investigate the association of PACs and the risk of recurrent stroke in patients with ischemic stroke in sinus rhythm.
Methods: The study was conducted as a cross-sectional study. 24-hour standard three-lead Holter ECG monitoring was performed for seven days and analyzed. Patients were separated into two groups based on the results of Holter ECG monitoring: those with subclinical AF and those with frequent PACs. Frequent PACs were characterized as more than fourteen PACs per hour and >3 PAC runs each 24 hours. Subclinical AF was defined as atrial fibrillation, atrial flutter, or atrial tachycardia events detected by implantable or wearable cardiac devices in people without AF symptoms and in whom clinical AF was not previously detected.
Results: 150 patients, consisting of 82 men (54.7% of the total) and 68 women (45.3%), with an average age of 60.9±13.5 years, were enrolled in the research. Based on the Holter findings, patients were separated into subclinical AF (n=54) and frequent PACs (n=96).During hospitalization, recurrent ischemic stroke was detected in 6 patients (11%) in the subclinical AF arm and 26 patients (26%) in the frequent PACs arm (p=0.03). Six patients died of whom 4 died after a recurrent stroke event in the hospital. In univariate analysis age [OR: 1.03, 95%CI (1-1.07), p=0.02], dyslipidemia [OR: 2.68, 95%CI (1.16-6.18), p=0.021] and frequent PACs [OR: 2.97, 95%CI (1.13-7.76), p=0.026] were found significant predictors of recurrent stroke. Furthermore, in multivariate logistic regression analysis only frequent PACs [OR: 2.69, 95%CI (1-7.17), p=0.048] was found independent predictors of recurrent stroke.
Conclusion: Frequent PACs on Holter analysis were significantly associated with recurrent ischemic stroke.
Risk factors for hospital mortality of patients with COVID-19 and 6-month follow-up of discharged patients
Authors: ARSLAN GÜLEN Tugba , İMRE Ayfer , BOZOK Taylan
Published: December 2022

Objective: COVID-19 continues to pose a public health threat globally. This study evaluated the risk factors of hospitalized patients associated with hospital mortality for COVID-19 and symptoms on days 14, 28, and 6th-month.

Methods: The study included 133 adults hospitalized due to COVID-19 between April 1, 2020 and June 30, 2020. Patient files were retrospectively reviewed. The demographic characteristics of the patients were evaluated by dividing them into two groups according to the clinical severity of COVID-19. (group 1: mild+moderate, group 2: severe+critical). Risk factors associated with mortality were revealed. Symptoms on day 14 and day 28 were questioned in person or by phone if patients were discharged and symptoms at 6 months were questioned by phone.

Results: Comparison of laboratory findings between the groups showed that patients in group 2 had lower serum lymphocyte count and higher levels of C-reactive protein, ferritin, D-dimer, procalcitonin, and troponin T at admission and during follow-up (p
The Effect of Low Magnitude High Frequency Vibration on Bone Healing by Clamp Method in Nonunion Tibial Fractures
Authors: CELİK Ferhat , BİLGİN Hakkı Murat , AKKOC Hasan , OZKUL Emin , GEM Mehmet , OZERDEM Mehmet Sirac , KARIKSIZ Mesut , ERDEM Mustafa , ELCİ Serhat
Published: December 2022

Introduction: This study aimed to investigate the clinical effect of Low Magnitude High Frequency Vibration (LMHFV) on nonunion tibial fractures, noninvasively.

Methods: The Experimental (n=5) and control (n=5) groups were age-matched and pooled based on the Nonunion Tibia Score System (NUSS) (p>0.05). LMHFV (0.35g, 50 Hz, 20 minutes x 4/day) was applied to the experimental group for three months by a mechanical stimulator that we developed using a ‘clamp method’. The control group was followed during three months without any application other than routine treatment. The results were evaluated using the Radiographic Union Score for Tibial Fractures (RUST) and American Orthopedics Foot and Ankle Score (AOFAS). No statistically significant difference was observed between the groups at the beginning and in the end of the 3- month application for RUST and AOFAS scores (p>0.05).

Results: Pain and function assessment, at the beginning and end of the study, as a part of The AOFAS scorewere not statistically different (p>0.05) in the control group. However, increases in pain and function AOFAS scores were statistically significant in the experimental group at the end of the 3- month application (p
Yüksek Hepatik Fibrozis – 4 (FİB-4) İndeksi ile Asemptomatik Tiroid Nodülleri Arasındaki İlişki
Authors: DEMİR Esra , TANRIKULU Onur , DEMİR Bülent
Published: December 2022

Amaç: Asemptomatik hastalarda yapılan tiroid ultrasonu sırasında rastlanan insidental tiroid nodüllerinin karaciğer fibrozis skoruolan hepatik Fibrozis – 4 (FİB-4) indeksi ile ilişkisinin araştırılmasıdir. . Yöntemler: Hastanemiz iç hastalıkları polikliniğine genel kontrol amaçlı başvurmuş, herhangi bir semptomu olmayan ve yapılan tiroid ultrasonunda tiroid nodülü tesbit edilen veardışık seçilen100 hasta ile tiroid nodülü olmayan ardışık seçilen 100 kontrol hastası retrospektif olarak taranarak toplam 200 hastaçalışmaya dahil edildi. Hastaların yaşları, cinsiyetleri, Tiroid USG sonuçları , Abdominal USG sonuçları her bir hasta için ayrı ayrı kaydedildi. Tüm hastalar içinhepatik FİB-4 indeks skorlarıhesaplandı.Tek değişkenli ve çok değişkenli analizler için Spearman'ın korelasyon analizi ve ikili lojistik modeli kullanıldı. Bulgular: Hasta grubunun yaş ortalaması, hepatosteatoz derecesi, kreatinin duzeyive FİB-4dahayüksekti (p
Dicle Üniversitesi Tıp Fakültesi Hastanesi’nde Bruselloz Seroprevalansı: RoseBengal Testi ve Brucella Coombs Test Sonuçları
Authors: TEMİZ Hakan , ÖZCAN Nida , ARAÇ Eşref , ÖZBEK Erdal
Published: December 2022

Amaç: Bruselloz dünyanın birçok ülkesinde ve ülkemizde en yaygın görülen zoonotik hastalıklardan biridir. Bu çalışmada; 2021 yılı içerisinde hastanemiz mikrobiyoloji laboratuvarına çeşitli klinik ve polikliniklerden bruselloz şüphesi ile gönderilen hasta serum örneklerinde çalışılan RoseBengal Testi (RBT)ve BrucellaCoombs Testi (BCT) aglütinasyon titrelerinin, bölgemizdeki bruselloz seroprevalansını belirlemek için retrospektif olarak irdelenmesi amaçlanmıştır.

Yöntemler: Hastalardan serolojik testlerde kullanılmak üzere kan örnekleri alındıktan sonra serumları ayrıldı. Tarama testi olarak RoseBengal lam aglütinasyon testi kullanılmıştır. Tarama testi pozitif bulunan hasta serumlarına, Brucella immuncapture aglütinasyon testleri uygulanmıştır. Çalışmamızda uygulanan testlerde, BCT yöntemiyle 1/320 ve üzeri bulunan titreler pozitif olarak değerlendirilmiştir.

Bulgular: Çalışmada değerlendirilen 5.196 bruselloz şüpheli hasta örneğinden; RBT pozitif olan 336 (%6,5) hasta bulunmuştur. RBT pozitif olan serumların 257 tanesinin (%76,5) BCT titresi 1/320 ve üzerinde pozitif olarak saptanmıştır. BCT seropozitifliği %62,2 oranında en sık 20-50 yaş grubunda görülmüştür. BCTseropozitifliğinin hastanın başvurduğu kliniğe göre dağılımında ise en sık başvuru yapılan klinik %47,6 oranında enfeksiyon hastalıkları polikliniği idi. BCT seropozitif serumların 176’sı (%52,4) kadın, 160’ı (%47,6) ise erkek hastalara aitti.

Sonuç: Bruselloz, fakültatif intrasellüler bakterilerle ortaya çıktığından birçok organ ve sistemi etkileyebilmektedir. Hastalığın tanısında kültür altın standart olmakla birlikte serolojik testler de sıklıkla kullanılmaktadır. Bu çalışma ile elde edilen retrospektif veriler doğrultusunda hastanemizde bruselloz seroprevalansı %5 olarak saptanmıştır. Bu çalışmada serolojik test sonuçlarını değerlendirerek bölgesel verilerin oluşturulmasında katkı yarattığımızı düşünmekteyiz.
Alzheimer Hastalarında Gözlenenİnsomnia Risk Faktörlerinin Değerlendirilmesi
Authors: ŞANLI Zeynep Selcan , BENGİ BOZ Pınar , EVLİCE Ahmet Turan
Published: December 2022

Giriş: Yaşlı hasta popülasyonu dünya çapında ve ülkemizde hızla artmaktadır. Evde yaşayan 65 yaş üstü yaşlıların neredeyse yarısı uyku bozukluğu çekmektedir. Demansta uyku bozuklukları, uykuya dalmakta veya uykuyu sürdürmekte zorluk, uyku bölünmesi, gezinme ve aşırı gündüz uykululuk gibi sorunlarla birlikte yaygındır. Tedavi edilmeyen uyku bozuklukları, demanslı hastalarda bilişsel ve davranışsal semptomları şiddetlendirebilir ve yatak partnerleri ile aile üyeleri için önemli bir stres kaynağıdır. Ayrıca; uyku bozuklukları tedavi edilmediğinde geceleri yaralanma riskini artırabilir, yaşam kalitesini bozabilir ve bakıcılar için sosyal ve ekonomik yükleri hızlandırabilir. Bu çalışmada Alzheimer hastalığı (AD) tanılı olgularda insomnianın hangi etkenlere bağlı olduğunun belirlenmesi amaçlanmıştır.

Yöntemler: Çukurova Üniversitesi Tıp Fakültesi(ÇÜTF) Anabilim dalı demans polikliniğinde takipli Alzheimer hastalığı tanılı 170 hasta çalışmaya dahil edildi. Olguların demografik verileri, komorbiditeleri, laboratuar bulguları dökümante edildi. Ayrıca tüm olgulara Minimental durum testi (MMSE) uygulandı. İnsomnia tanısı InternationalClassificationof SleepDisorders-ThirdEdition(ICSD-3) tanı kriterlerine göre konuldu. Tüm sonuçlar gruplar arasında karşılaştırıldı. Verilerin istatistiksel analizi için SPSS programı 20.0 sürümü kullanıldı, p
Miyokard Enfarktüsü Hastalarında Nesfatin Düzeyi ve NesfatininTroponin ve CRP ile Korelasyonu
Authors: ADIYAMAN Mehmet Şahin , CANPOLAT ERKAN Revşa Evin , KAYA İlyas , ABA ADIYAMAN Özlem
Published: December 2022

Amaç: Miyokard enfarktüsü (MI), kardiyovasküler hastalık kaynaklı mortalite ve morbiditenin başlıca sebeplerindendir. Aterosklerotik plak rüptürü sonucu gelişen akut tromboz en önemli nedendir. Gıda alımı ve enerji homeostazında etkili olan nesfatin araştırılan belirteçlerdendir. Çalışmamızda miyokard enfarktüsü ile nesfatin düzeyi arasındaki ilişkiyi tespit etmeyi amaçladık. Ayrıca nesfatin düzeyinin troponin ve CRP ile ilişkisini açıklamayı planladık.

Yöntemler: Etik kurul onayı alınarak yapılan çalışmamıza, yeni tanı almış ve yatırılarak koroner anjiografi yapılmış akut koroner sendrom (AKS) hastaları dahil edildi. Obezite, kronik böbrek hastalığı, diabetes mellitus hastalığı olanlar dışlandı. Kontrol grubuna troponin değerleri yükselmeyen ve normal koroner anatomi tespit edilen 60 hasta dahil edildi. MI grubunda başvuru Ekg’sinde>2 mm st segment elevasyonu görülerek primer perkütan girişim yapılan 59 MI hastası değerlendirildi. Tüm hastalarda demografik bilgiler, hemogram, serum nesfatin, troponin, c-reaktif protein (CRP), lipid paneli ve diğer rutin biyokimyasal parametreler bakıldı. SPSS 22 istatistik paket programı kullanıldı.

Bulgular: MI grubunda troponin, LDL, CRP, WBC değerleri anlamlı düzeyde yüksek izlendi (p
Romatoid Artritli Hastalarda Statik ve Dinamik Pupillometri Parametrelerinin Değerlendirilmesi
Authors: DURSUN Mehmet Emin , ERDEM Seyfettin , KARAHAN Mine , AVA Sedat , HAZAR Leyla , DURSUN Birgül , KEKLİKÇİ Uğur
Published: December 2022

Amaç: Romatoid artritli yetişkin hastalarda statik ve dinamik pupilla yanıtlarını sağlıklı yetişkinler ile karşılaştırmayı amaçladık. Yöntemler: Bu prospektif çalışmaya, oftalmolojik muayenede herhangi bir patoloji saptanmayan romatoid artritli yetişkin hastalar ile benzer yaş ve cinsiyetteki sağlıklı yetişkinler dâhil edildi. Statik ve dinamik pupilla yanıtları otomatik pupillometri cihazı (MonPackOne; Metrovision, Perenchies, Fransa) kullanılarak ölçüldü. Statik pupillometri ölçümlerinden skotopik, mezopik, düşük fotopik ve yüksek fotopik pupil çapları kaydedildi. Dinamik pupillometri ölçümlerinden ise dinlenme pupil çapı, pupil kontraksiyon amplitüdü, pupil kontraksiyon latansı, pupil kontraksiyon süresi, pupil kontraksiyon hızı, pupil dilatasyon latansı, pupil dilatasyon süresi ve pupil dilatasyon hızı değerleri kaydedildi. Bulgular: Çalışmaya 32 romatoid artritli hasta, 30 sağlıklı kontrol alındı. Romatoid artrit ve kontrol grubunda yaş ve cinsiyet açısından istatistiksel anlamlı fark izlenmedi (Sırasıyla; p=0.621, p=0.806). Romatoid artrit grubunda statik pupilla yanıtlarından skotopik pupil çapı kontrol grubuna göre anlamlı olarak yüksekti (p=0.02). Mezopik, düşük fotopik ve yüksek fotopik ortamlardaki pupil çapları arasında romatoid artrit grubu ile kontrol grubu arasında istatiksel olarak anlamlı fark yoktu. Dinamik pupillometri ölçümlerinden pupil dinlenme çapı romatoid artrit grubunda istatiksel olarak anlamlı derecede geniş olarak ölçülürken (p
Management of Spine-Related Problems Following Sport Injuries: A Review Article
Authors: Roohollahi Faramarz
Published: December 2022

Context: Athletes have routine activity programs, and better physical health is expected among them. There is limited information about the connection between athletes' injuries during sports activity and their future health status. Objectives: The prevalence of spine changes related to sports activities and what risk factors were associated with these events in athletes. Method: SCOPUS, EMBASE, and Web of Science were used for article searching. Results: Sports injuries in sports happen frequently. Our data is limited to introducing sports with the highest risk of injury. A history of sports injury, an intense training program, and years of sports activities are factors predicting injury. It has been seen that former top male athletes have more activity than age-matched control individuals. Conclusions: Spinal injury management in athletes needs a proper diagnosis, work-up, and complex rehabilitation plans; otherwise, it can lead to spinal complaints in the future. Rest, appropriate analgesia, and rehabilitation are the three main primary treatments. The usage of orthoses is not recommended for these injuries in general.
Noninvasive Vagus Nerve Stimulation in the Treatment of Methamphetamine Use Disorder: A Review Article
Authors: Ghazvini Hamed , Zarghami Mehran , Rafaiee Raheleh , Beirami Elmira , Seyedhosseini Tamijani Seyedeh Masoumeh
Published: December 2022

Context: Methamphetamine (MA) use and the mortality it causes are increasing worldwide. The neurobiological mechanisms underlying the destructive effects of MA use are complex; however, there is much evidence that MA induces the dysfunction of monoaminergic transmission and causes oxidative stress, neuroinflammation, gliosis, and apoptosis. These toxic effects are associated with cardiotoxicity and neurotoxicity and with an imbalance in the autonomic nervous system, which altogether manifest themselves in clinical symptoms, such as neuropsychiatric disorders and cardiovascular diseases. Evidence Acquisition: There is no approved treatment for methamphetamine use disorder (MUD) despite all efforts made to date. The behavioral and pharmacological approaches currently used for the treatment of MUD are not completely effective. In this study, it is hypothesized that the stimulation of the vagus nerve and biological pathways underlying the processes of this stimulation might be effective as adjunctive therapy. Results: Despite the potential effects of vagus nerve stimulation (VNS) to improve MUD, no study has yet examined the clinical potential effects of VNS in patients with the disorder. Conclusions: Therefore, further studies, including experimental and clinical trials, are needed to examine the effects of VNS on MUD.
Decoding Selective Attention and Cognitive Control Processing Through Stroop Interference Effect: An Event-Related Electroencephalography-Derived Study
Authors: Kamali-Ardekani Razieh , Tavakkoli Neishabouri Alireza , Rabiei Mojtaba , Alizadeh Mohammadreza , Yoonessi Ali , Shafaghi Lida , Hadjighassem Mahmoudreza
Published: December 2022

Background: The process of cognitive control and resultant selective attention construct the shared root of a continuum of neurocognitive functions. Efficient inhibition of task-irrelevant information and unwanted attributes has been evaluated through various paradigms. Stroop tasks in different forms could provide a platform for detecting the state of this type of inhibition and selective attention. Computational modeling of electroencephalography (EEG) signals associated with attentional control could complement the investigations of this discipline. Objectives: We used a machine learning-based classification to examine whether earlier or later epochs are more representative. So, through the present preliminary investigation, Gaussian SVM models were trained on the early (150 - 300 ms) and late (350 - 500 ms) intervals. Methods: Ninety-six trials of a three-condition Color-Word Stroop task were performed while recording EEG. All subjects (9 participants) were right-handed (20 - 25 years), and half were male. Three-condition signal epochs were redefined as two conditions: (1) differentiated incongruent epochs (DIe), which are incongruent epochs that their equivalent congruent epochs are subtracted from and (2) neutral epochs, in which intervals of 150 - 300 ms and 350 - 500 ms post-stimulus were extracted. Preprocessed data were then analyzed, and the whole EEG epoch was considered the variable to be compared between conditions. An acceptably fitted support vector machine (SVM) algorithm classified the data. Results: For each individual, the comparison was made regarding DIe and neutral epochs for two intervals (150 - 300 and 350 - 500 ms). The SVM classification method provided acceptable accuracies at 59 - 65% for the 150 - 300 ms interval and 65 - 70% for the 350 - 500 ms interval within individuals. Regarding frequency domain assessments, the Delta frequency band for these two intervals showed no significant difference between the two conditions. Conclusions: The SVM models performed better for the late event-related epoch (350 - 500 ms) classification. Hence, selective attention-related features were more significant in this temporal interval.
Imaging Findings of a Renomedullary Interstitial Cell Tumor: A Case Report
Authors: Song Seung Ju , Lee Young Hwan , Kim Youe Ree
Published: December 2022

Introduction: Renomedullary interstitial cell tumors are benign tumors of renal medulla. They are usually asymptomatic, and preoperative diagnosis based on radiological findings is challenging. Therefore, in most clinical situations, nephrectomy is ultimately performed for differential diagnosis. Case Presentation: A 54-year-old woman presented to our hospital with hematuria. An incidental mass in the left kidney was detected on abdominal computed tomography (CT) scan. The mass showed iso-attenuation to renal parenchyma in the pre-contrast image and hypo-attenuation in the portal venous phase; however, some enhancement was observed in the central portion of the mass. Based on contrast-enhanced ultrasonography (CEUS) after one year, a slight septum-like enhancement was observed in the central portion of the mass in the venous phase. In dynamic contrast-enhanced T1- and T2-weighted magnetic resonance images (MRI), the mass showed a low signal intensity, and delayed persistent enhancement was observed in 10- and 15-minute delayed phases. The mass was finally diagnosed as a renomedullary interstitial cell tumor. Conclusion: The imaging findings of renomedullary interstitial tumors included a low-signal-intensity mass of renal medulla on T1- and T2-weighted MRI and delayed enhancement on CEUS and dynamic MRI.
Temporal Trend and Spatial Distribution of Drug Poisoning in Semnan Province: A Retrospective Longitudinal Study
Authors: Babakhanian Masoudeh , Mamashli Khadijeh , Ansariniya Faezeh , Rezaie Somayeh , Azadi Hamed , Ghazanfarpour Masumeh , Rahimi Pordanjani Sajjad
Published: December 2022

Background: Substance abuse and the risks of its consequences are the major public health problems in the world and Iran. Objectives: The objective of the present study is determination the epidemiological status and spatial distribution of high-risk and low-risk clusters along with estimating the relative risk of drug poisoning in Semnan in 8 years. Methods: A descriptive-analytical and retrospective longitudinal study was conducted that examined all 3360 poisoned patients who referred to the hospitals of Semnan province from 2011 - 2018. The total number of visits was received and analyzed by year with the relevant diagnostic code in ICD-10 from hospitals of the province, and data were analyzed using Joinpoint regression analysis, global Moran’s index and Kuldorff's spatial statistic scan at a significant level of 0.05. Results: The number of clients varied from 219 in 2011 to 570 in 2015. The patients' mean age was 26.7 years. The average annual number of cases per one hundred thousand individuals (annual cases/100000) was 598.4. The AAPC of the incidence of drug poisoning was 9.8 and significant in the whole province, demonstrating that the incidence of poisoning increased by an average of 9.8% per year in the whole province from 2011 to 2018. Semnan County with LLR = 533.07 was the most likely low-risk cluster, and Shahroud County was the most likely high-risk cluster with LLR = 219.94. Conclusions: Drug policies need to be adapted to the geographical differences in the place death. After clustering regions in poisoning incidents, the necessary interventions can be concentrated for these specific geographical locations.
Relationship of Parental Alexithymia and Neglect with Healthy Children's Maladjustment in Families with and Without Autistic Children
Authors: Hesami Elham , Bakhshani Nour Mohammad , Raisi Mahdi
Published: December 2022

Background: Family factors predict the incidence of developmental incompatibilities and psychological disorders. Moreover, having a child with autism can be an overwhelming experience for some families. Objectives: This study aimed to investigate the role of neglect and alexithymia in parents with or without an autistic child on the maladjustment level of their healthy children. Methods: In this descriptive-correlational study, two groups of families with (n = 16) and without (n = 16) an autistic child in the cities of Zahedan and Birjand were selected by the convenience sampling method. Data were collected using the Toronto Alexithymia Scale, Child Abuse Questionnaire (self-report scale), and Rutter's Child Behavior Disorders Questionnaire (parent form), which were then analyzed using Pearson's correlation coefficient and stepwise multiple regression test. Results: Significant results were obtained for specific and joint relationships between parental alexithymia and neglect and maladjustment of their healthy children (P = 0.041). However, the results obtained for the effect of the presence or absence of an autistic child in the family as a moderating variable were not significant (P = 0.556). Parental alexithymia had a significant positive correlation (r = 0.565, P = 0.001), and parental neglect had a significant negative correlation (r = -0.393, P = 0.029) with maladjustment of healthy children in the family. Conclusions: Neglect and alexithymia in parents specifically and jointly correlate significantly with their healthy child's maladjustment. However, the presence or absence of an autistic child in the family has no significant effect on this relationship. Parental alexithymia is a stronger predictor of the maladjustments of healthy children.
Investigating the Relationship Between Special Medical Waste Disposal and Needle Sticking of Staff in Hospitals of Iran University of Medical Sciences
Authors: Maleki Mohammadreza , Pourasghari Hamid , Nafar Hamideh
Published: December 2022

Background: Infectious hospital waste, including needles and sharp instruments, is one of the most important causes of needle sticks. Objectives: The study aimed to investigate the factors affecting the disposal of special medical waste with needle sticks among healthcare workers in hospitals at the Iran University of Medical Sciences. Methods: This descriptive-analytical, retrospective, and cross-sectional study were done regarding the data in the autumn of 2019. Among 6119 medical-service staff, 180 subjects have been exposed to the needle stick at least once. Data were collected in two parts. The data were analyzed using correlation tests by SPSS software version 25. Results: The most devices leading to injury were needles (58%), angiocatheter (21%), ampoules (17%), suture needles (12%), scalpels (9%), other tools (8%), and razor blades (7%). The five wards with the highest needle sticks were the operating room (24.44%), surgery (22.22%), emergency (15%), internal wards (10%), and paraclinical (8.33%). Also, several factors, such as work shifts and the amount of work experience of individuals, can play an essential role in the rate of needle stitching of medical personnel. Importantly, we found a significant relationship between the volume of medical waste and employee needlestick rates. Conclusions: According to the results, we found a significant positive relationship between the volume of medical waste and employees' needle sticking rate. The observance of standard guidelines and the development and increase of occupational safety protection training courses have the most significant role in reducing needle sticks.
Performance Challenges Faced by “Behvarzes” as Community Health Workers of Iran: A Systematic Review of Literature
Authors: Gharibi Farid , As'habi Atefeh , Nazari Maryam , Haghi Mehdi , Ebrahimi Tavani Masoumeh
Published: December 2022

Context: Iranian community health workers (known as behvarzes) have played an undeniable role in improving the health status of the rural community in recent decades. Therefore, this study aimed to identify the performance challenges faced by behvarzes using a literature review. Methods: This systematic review searched the Web of Science, Scopus, Science Direct, Springer, PubMed, ProQuest, SID, and Magiran databases/search engines in January 2020. There were 2 inclusion criteria, namely articles published in English or Persian languages and those published in or after 2000. The search strategy resulted in the retrieval of 1,472 primary articles, 16 of which were finally included in the study, and their related contents were entered into extraction tables. Then, the identified challenges were categorized based on the context, input, process, and product (CIPP) model. Results: The study results recognized the major challenges in 5 dimensions, including context (i.e., changes in societal, cultural, demographical, and epidemiological characteristics of rural communities), input (i.e., inadequate number of behvarzes, their insufficient competencies, and limited resources), process (i.e., increase in healthcare process complexity and the number of bahvarzes’ tasks and managerial problems), output (i.e., decrease in the quality, efficiency, accessibility, continuity, utilization, and effectiveness of services provided by behvarzes, poor health literacy of rural population and their weak involvement in health affairs, and emerging mental health problems in behvarzes), and outcome (i.e., low equity, urban-rural disparity in the diagnosis and treatment of diseases, and dissatisfaction of behvarzes and caregivers). Conclusions: This study revealed numerous important challenges faced by behvarzes, which need effective intervention by policymakers.
Faktor-Faktor yang Berhubungan dengan Tingkat Stres pada Mahasiswa dalam Proses Pembelajaran Daring selama Pandemi COVID-19
Authors: Surury Istianah , Nurjanah Mitha , Ardiani Azhar Hana
Published: December 2022

Pembelajaran daring merupakan solusi di masa pandemi COVID-19, namun juga memiliki kekurangan. Menghadapi metode pembelajaran daring membuat mahasiswa merasa cemas. Cemas yang berkepanjangan dapat menyebabkan stress yang mengganggu aktivitas. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kejadian tingkat stress pada mahasiswa dalam proses pembelajaran daring selama pandemi COVID-19 di Fakultas Kesehatan Masyarakat Universitas Muhammadiyah Jakarta. Penelitian ini merupakan penelitian kuantitatif dengan desain study cross-sectional. Sampel berjumlah 100 mahasiswa dengan teknik sampling Two Stage Cluster dan dilakukan pada Oktober-Desember 2020. Data dikumpulkan menggunakan kuesioner. Hasil penelitian menunjukkan, variabel sarana prasarana (p-value=0.057) dan kesulitan memahami materi (p-value=0.045) berhubungan dengan tingkat stress dalam pembelajaran daring. Variabel yang tidak berhubungan adalah status ekonomi (p-value=0.621), kendala jaringan (p-value=0.892) dan tugas perkuliahan (p-value=0.442). Faktor sarana dan prasarana seperti gadget memiliki pengaruh yang signifikan dalam memicu tingkat stress pada mahasiswa. Ketika sarana tersebut tidak dapat digunakan untuk mengakses perkuliahan, maka mahasiswa menjadi kesulitan mengikuti pembelajaran daring. Begitu pula ketika materi yang disampaikan tidak dapat dipahami, akibatnya mahasiswa tidak dapat memahami materi dengan baik, dan ini memicu stress mahasiswa.

Kata kunci: COVID-19, Mahasiswa, Pembelajaran Daring, Tingkat Stress.
Variabilitas Iklim (Curah Hujan, Suhu dan Kelembaban) Dengan Kejadian Diare Di Kota Tangerang Selatan Tahun 2015 – 2019
Authors: Siti Riptifah Tri Handari  , Taqiyah Hamidah
Published: December 2022

Tingginya morbiditas dan mortalitas kejadian diare di negara berkembang menjadi salah satu masalah kesehatan masyarakat. Beberapa faktor utama meningkatnya kejadian diare antara lain adanya perubahan iklim dan sanitasi lingkungan yang buruk. Penelitian ini bertujuan untuk melihat hubungan antara iklim (curah hujan, suhu dan kelembaban) dengan kejadian diare di Kota Tangerang Selatan tahun 2015 – 2019. Penelitian ini menggunakan studi ekologi. Data yang digunakan bersumber dari laporan kasus diare dari Dinas Kesehatan Kota Tangerang Selatan sedangkan data iklim seperti curah hujan, suhu udara dan kelembaban berumber dari data BMKG wilayah II Ciputat dari tahun 2015 – 2019. Hasil analisis menggambarkan rata-rata kejadian diare dari tahun 2015 – 2019 sebanyak 799 penderita, curah hujan 311.8 mm, suhu udara 27.90C dan kelembaban 79.3%. Terdapat hubungan antara curah hujan dengan kejadian diare dengan korelasi negatif (p=0.028; r= -0.284), berkorelasi negatif antara suhu udara dengan kejadian diare (p=0.001; r= -0.422), dan berkorelasi positif kelembaban dengan kejadian diare (p=0.0005; r=0.548). Variasi iklim memiliki hubungan yang bermakna dengan kejadian diare di Kota Tangerang Selatan tahun 2015 – 2019.