bluuebunny/crossref_metadata_2025 huggingface dataset:
The digital competence of Chinese higher education students and the linkage with their career adaptability
Authors: Zhou Na , Wang Jiping , Liu Xin , Yang Liu , Jin Xinglin
Published: July 2023

Purpose

Recently, digital competence has become one of the most important work competencies of employees. This study investigated students' digital competence in the context of Chinese higher education and examined digital competence's relationship with students' career adaptability.

Design/methodology/approach

The participants were 298 Chinese higher education students from both universities and colleges. MANOVA (Multivariate Analysis of Variance) was carried out through SPSS (Statistical Package for the Social Sciences) 26.0 to examine whether digital competence varied with the students' personal characteristics, i.e. gender, grade level and school type. In addition, the structural equation model was employed with Mplus 8.3 to analyse the relationship between digital competence and career adaptability as well as the mediation role of digital informal learning and academic performance.

Findings

The descriptive statistics revealed that students performed best in the safety construct, whilst worst in the digital content creation construct. The result of MANOVA showed that the digital competence of the participants significantly varied with participants' gender, school type and grade level. Furthermore, the structural equation model results demonstrated that higher education students' digital competence was positively associated with the students' career adaptability. And the mediation role of digital informal learning and academic performance was also confirmed.

Originality/value

To the authors' knowledge, this is the first study focussing on the relationship between digital competence and career adaptability. In particular, both working and learning perspectives were considered to explore this relationship. Besides, the authors also displayed Chinese higher education students' digital competence with consideration of different districts and school types.
Governing land use planning in pursuit of customary tenure security: A case of Kilombero District in rural Tanzania
Authors: Gwaleba Method Julius , Kongela Sophia Marcian , Kombe Wilbard Jackson
Published: July 2023

Purpose

This paper aims to explore the role of participatory governance to actors’ participation in land use planning for tenure security in rural Tanzania. Three case studies where land use planning project implemented were selected to make assessment on how local actors were involved in the process.

Design/methodology/approach

This paper uses qualitative research methods, whereby semi-structured interviews with village landholders and key informants were conducted to get their perspectives on land use decisions and land tenure (in)security. Besides, focus group discussions with the village landholders were also used.

Findings

The research findings indicate low participation of local actors in land use planning process. Decisions on land use by the local actors were very minimal. Further, communication between the involved actors was also difficult.

Originality/value

The study offers insights on participatory governance into land use planning for tenure security. The study develops a framework to improve land use planning process toward tenure security outcome. A tri-partite strategy consisting of enabling mechanisms of governance capacity, institutional capacity and converging discourses articulates a framework for the evolution in the degree of local actors’ participation to improve security of land rights through land use planning process in rural Tanzania.
Outcomes of endovascular, open surgical and autotransplantation techniques for renal artery aneurysm repair: a systematic review and meta‐analysis
Authors: Choksi Harsham , Singla Animesh , Yoon Peter , Pang Tony , Vicaretti Mauro , Yao Jinna , Lee Taina , Yuen Lawrence , Laurence Jerome , Lau Howard , Pleass Henry
Published: July 2023

Background

Renal artery aneurysms (RAA) can be repaired with endovascular exclusion (EVR), open repair (OR), or ex‐vivo repair with renal autotransplantation (ERAT). This systematic review compares repair indications, aneurysm characteristics, and complications following these interventions.

Methods

A systematic review of databases including MEDLINE, PUBMED, and EMBASE by two independent reviewers for studies from January 2000–November 2022. All studies evaluating repair indications, RAA morphology, morbidity and mortality following EVR, OR, and ERAT were included.

Results

A total of 38 studies were included with 1540 EVR, 2377 OR and 109 ERAT subjects. Increasing aneurysm size, or diameters >20 mm, were the most common repair indications across EVR and OR (n = 537; 48%), and ERAT (n = 23; 52%). All ERAT repairs were at or distal to renal artery bifurcations (n = 46). Meta‐analyses demonstrated significantly shorter length of stay (LOS) with EVR compared to OR (mean difference −4.06, 95% confidence interval (CI) −5.69 to −2.43, P < 0.001). No significant differences were found in mean aneurysm diameter (P = 0.23), total complications (P = 0.17), and mortality (P = 0.85). Major complications (Clavien‐Dindo ≥III) across studies most commonly included acute renal failure (EVR 4.9% vs. OR 7.0%). Nephrectomy was the most common major complication in ERAT (5.5%).

Conclusions

Outcomes following EVR and OR of RAAs are comparable. EVR offers a shorter LOS, with no difference in morbidity or mortality. ERAT is currently only utilized for distal RAAs, however carries higher risk of infarction and nephrectomy necessitating specialized expertise or algorithms to assist appropriate selection of repair methods.
What can the experiences of rural women in Solomon Islands teach us about innovation in aquatic food systems?
Authors: Batalofo Margaret , Aruhe'eta Pollard Alice , Ride Anouk , Hauona Edlyn , van der Ploeg Jan , Isihanua Matthew , Roscher Matthew , Sukulu Meshach , Eriksson Hampus
Published: July 2023

In Solomon Islands, women's groups play an important role in promoting socially inclusive development and women's empowerment. In this paper, we summarise the experiences of a 5‐year participatory action research partnership to enhance rural livelihood activities based on aquatic foods. The women's savings groups that participated in this research identified solar‐powered freezers as an innovation suitable to their skills and environment. The 12 freezers we used in our partnership to pilot this innovation had tangible benefits. More than 700 unique users accessed the freezers, 3900 kg of fish was stored and over USD6,000 was saved in total; however, accumulation of savings varied greatly between groups. The women's groups demonstrated that operating solar‐powered freezers can be financially viable, and the innovation integrated well with their livelihood activities. This conclusion provides an alternative to dominant development narratives, which tend to focus on building large‐scale infrastructure, and often exclude women. Existing marketing skills and cooperation were strengths on which the women built. Poor‐quality technology was the biggest impediment to success. Solving this basic problem should be a priority for any future cold‐storage initiative.
Transcranial direct current stimulation over dorsolateral prefrontal cortex improves postural stability in non‐specific chronic low back pain patients with high fear of pain: A randomized sham‐controlled trial
Authors: Ehsani Fatemeh , Masoudi Mona , Hedayati Rozita , Jaberzadeh Shapour
Published: July 2023

Deficits in postural stability in response to environmental challenges are seen in chronic low back pain (CLBP) patients with high fear of pain (HFP). Hence, it is essential to follow effective approaches to treat postural stability deficits and improve the health status of these patients. The current study aimed to compare the effects of cathodal and anodal transcranial direct current stimulation (c‐tDCS and a‐tDCS) over the left dorsolateral prefrontal cortex (DLPFC) on postural stability in non‐specific CLBP patients with HFP. In this randomized clinical trial study, 75 patients were randomly assigned to left DLPFC a‐tDCS, left DLPFC c‐tDCS and sham stimulation groups (n = 25 in each group). All groups received a single‐session 2 mA tDCS for 20 min, but the stimulation was slowly turned off after 30 s in the sham group. Before, immediately, 24 h and 1 week after the interventions, postural stability indices were assessed using a Biodex Balance System. A significant reduction in most indices was shown in both a‐tDCS and c‐tDCS groups after interventions (immediately, 24 h and 1 week follow‐up) during static and dynamic postural tasks compared with the sham tDCS group (p < .01). In addition, some tests showed a significant difference between a‐tDCS and c‐tDCS (p < .05). The findings indicated positive effects of both a‐tDCS and c‐tDCS on the left DLPFC, with more efficacy of a‐tDCS on postural stability in LBP patients with HFP.
Comparing migratory connectivity across species: The importance of considering the pattern of sampling and the processes that lead to connectivity
Authors: Cresswell Will , Patchett Robert
Published: July 2023

Measuring the degree of migratory connectivity – how much and where different populations of species mix as they migrate over their annual cycle – is important because it informs the understanding of the evolution of migration, how populations will be affected by both habitat and climate change, and which areas to prioritize for conservation. But existing measures of connectivity may be difficult to compare because they measure different things and are confounded by sampling bias. Here we use tagging data from all available published landbird tracks up to July 2019 (224 populations, 86 species and 1524 individuals tracked in the three main global flyways) to identify robust measures to compare migratory connectivity across species. We consider two widely used descriptive measures: (1) degree of breeding population overlap on the non‐breeding grounds and (2) Mantel correlation, which tests the degree of spatial autocorrelation between the breeding and non‐breeding individuals; as well as one causative measure of the main process that leads to connectivity patterns: migratory spread of individuals from the same breeding population across the non‐breeding area. We investigated the sensitivity of these three measures to the distance between breeding locations of sampled populations (breeding distance) and their sample size. We also considered the confounding effects of migration distance because longer migrations decreased overlap and increased Mantel correlations and migratory spread. We found that the degree of overlap between breeding populations on the non‐breeding grounds decreased with increasing breeding distance and increased with increasing sample size. Mantel correlation coefficients also increased significantly with increasing breeding distance; sample size did not affect accuracy, but precision was greatly improved above a sample size of about 15 individuals. Migratory spread, however, was independent of breeding distance; sample size had only small effects on accuracy and precision, with no significant effects when more than four individuals per population were included. Furthermore, migratory spread was highly positively correlated with the maximum non‐breeding range. Overlap and Mantel correlations were highly confounded by the spatial pattern and amount of sampling, whereas migratory spread was relatively unconfounded, even by migratory distance. Although any descriptive migratory connectivity measure can help set priorities by determining current areas for conservation on the non‐breeding grounds, migratory spread, which leads to these patterns, needs fewer data, is comparable, and gives information on evolutionary flexibility and so ability to deal with changing habitat and climate.
RETRACTED: Influence of closed‐incision negative‐pressure wound therapy on the incidence of surgical site wound infection in patients undergoing spine surgery: A meta‐analysis
Authors: Liu Zhi‐Shen , Tian Shao‐Bin
Published: July 2023

The present meta‐analysis was conducted to comprehensively assess the impact of closed‐incision negative‐pressure wound therapy (ciNPWT) on the incidence of surgical site infections (SSIs) in patients undergoing spinal fusion surgery, thereby aiming to provide evidence‐based support for the prevention of postoperative wound infections during spinal surgery. Relevant studies pertaining to the application of ciNPWT in spinal surgery were retrieved through searches of the PubMed, Embase, MEDLINE and Cochrane Library databases, spanning from their inception to May 2023. The literature screening and data extraction were performed by two researchers based on predefined inclusion and exclusion criteria, followed by a quality assessment of the included studies. Meta‐analyses were performed using the odds ratios (ORs) and standardised mean differences (SMDs) as effect variables. RevMan 14.0 and STATA 17.0 were employed for meta‐analysis of the extracted data. In total, eight articles involving 1198 patients, including 391 in the experimental group and 807 in the control group, were included. The meta‐analysis results revealed that ciNPWT significantly reduced the incidence of SSIs in patients undergoing spinal fusion surgery (OR, 0.39; 95% CI: 0.22–0.67, p = 0.0007); however, it did not lead to a reduction in hospital stay duration (SMD: −0.48, 95% CI: −0.98 to 0.01, p = 0.06). Existing evidence suggests that ciNPWT has a positive impact on patients undergoing spinal fusion surgery, as it significantly reduces the incidence of postoperative surgical site wound infections; however, it does not result in a shorter hospital stay for patients.
Stratum corneum compliance enhances tactile sensitivity through increasing skin deformation: A study protocol for a randomized controlled trial
Authors: Sakaguchi Saito , Saito Kaoru , Arakawa Naomi , Konyo Masashi
Published: July 2023

Background

Tactile sensation plays a crucial role in object manipulation, communication, and even emotional well‐being. It has been reported that the deformability of skin (also described as skin compliance) that shows a large mechanical response to stimuli is associated with high tactile sensitivity. However, although the compliance of the stratum corneum, the outermost layer of skin, can change daily due to skin care and environmental factors, few studies have quantified the effect of the stratum corneum on tactile sensation.

Aims

We investigated the changes in tactile sensitivity resulting from skin hydration and identified corresponding alterations in the compliance of the stratum corneum.

Methods

A randomized controlled trial was conducted. Participants were randomly assigned to an intervention group (n = 20) that had a moisturizing cream applied to their cheeks or a control group (n = 19) that had Milli‐Q water applied to their cheeks. Tactile discrimination performance was assessed using psychophysical techniques before and after application. The water content, mechanical response characteristics, and penetration of PEG/PPG‐17/4 dimethyl ether from the cream in the stratum corneum were evaluated to identify hydration effects. Skin deformations occurring during tactile sensation were measured concurrently using a suction device employed for tactile stimulation.

Results

Tactile sensitivity was increased in participants who had cream applied to the skin surface, while no significant change was observed in participants who received Milli‐Q water. The improved discrimination of tactile stimulus intensity was directly related to the magnitude of skin displacement. The higher water content of the stratum corneum due to cream application decreased the dynamic modulus of elasticity of the stratum corneum and increased the skin's extensibility in response to tactile stimuli.

Conclusions

Hydrating the stratum corneum significantly enhances tactile sensitivity and is accompanied by an increase in skin extensibility, a factor in tactile intensity perception. The compliance of the thin stratum corneum layer plays a crucial role in tactile experiences that involve skin stretching.
Inequity in end‐of‐life care for patients with chronic liver disease in England
Authors: Woodland Hazel , Buchanan Ryan M. , Pring Andy , Dancox Mark , McCune Anne , Forbes Karen , Verne Julia
Published: July 2023

Background and Aims

The World Health Assembly recommends integration of palliative care into treatment of patients with any life‐limiting condition, yet patients with non‐malignant disease are less likely to receive specialist palliative care (SPC). This study compares SPC offered to patients with hepatocellular carcinoma (HCC) versus patients with chronic liver disease without HCC (CLD without HCC).

Methods

Patients who died from CLD or HCC over 5 years (2013–2017) in England were identified using a dataset linking national data on all hospital admissions (Hospital Episode Statistics – HES) with national mortality data from the Office for National Statistics (HES – ONS). The primary outcome was the proportion of patients who received inpatient SPC in their last year of life (LYOL). Secondary outcomes were (1) early inpatient SPC input and (2) the proportion dying in a hospice. The outcomes were compared between patients with HCC and CLD without HCC.

Results

29 669 patients were identified, 8143 of whom had HCC. Patients with HCC were significantly more likely to receive inpatient SPC input—adjusted OR 3.74 (95% CI 3.52–3.97) and early inpatient SPC input—adjusted OR 7.26 (95% CI 6.38–8.25) and die in a hospice OR 8.23 (95% CI 7.33–9.24) than patients with CLD without HCC.

Conclusions

These data highlight the stark inequity in access to SPC services between patients with HCC and patients with CLD without HCC in England. Addressing these inequities will improve end‐of‐life care for patients with CLD.
Public expenditure, risk sharing and economic growth
Authors: Zhang Lifeng
Published: July 2023

We develop an endogenous growth model with expanding variety in which asymmetric information frictions arise when R&D ﬁrms need access to external funding to ﬁnance their R&D investments and public expenditure aﬀects the magnitude of hidden costs, in turn affecting the severity of asymmetric information frictions. We show that public expenditure affects growth by influencing risk sharing, thereby identifying a new channel, unlike the standard mechanism used in the literature that emphasizes the role of public expenditure in directly improving the productivity of the private sector.
Resource nationalism among Russian academics: A centre‐periphery pattern?
Authors: Tinti Alessandro , Basile Linda , Cilento Marco
Published: July 2023

Under Putin's tenure, the geopolitical representation of Russia as an ‘energy superpower’ has become a powerful mainstay for the restoration of a global status and a revanchist foreign policy. This article seeks to assess the extent to which such a nationalist narrative is prevalent among Russian academics in the oil and gas sector. Using a survey administered to research and teaching staff in selected industrial universities in 2021, we found partial confirmation of the relevance of centre‐periphery relations and that nationalist attitudes are aligned with a state‐centric approach. However, this perspective does not necessarily entail opposition to industry privatisation or foreign partnerships. These findings highlight the inadequacy of a simplistic privatisation/nationalisation dichotomy in capturing the hybrid nature of resource governance in petro‐states. Additionally, our study suggests that resource nationalism plays a role in shaping experts' support for the government's energy policy. These findings contribute to the literature on resource nationalism and suggest potential avenues for future research exploring the role of higher education institutions in shaping resource governance.
Activation of receptor‐interacting protein 3‐mediated necroptosis accelerates periodontitis in mice
Authors: Yue Yuan , Chan Weicheng , Zhang Jing , Liu Jie , Wang Min , Hao Liang , Wang Jiajia
Published: July 2023

Objective

To investigate the involvement and role of receptor‐interacting protein 3 (RIP3)‐mediated necroptosis in periodontitis.

Methods

A periodontitis murine model was established by oral infection with Porphyromonas gingivalis, and activation of necroptosis pathway was identified by immunohistochemistry. Adeno‐associated virus was used to knock down Rip3 and the effect of Rip3 knockdown on periodontal inflammation was examined by Micro‐CT, qRT‐PCR and histological staining. In vitro, P. gingivalis‐LPS was used to infect fibroblast cell line L929 and siRNA was used to knock down Rip3. Necroptosis pathway signalling and inflammation in cells were detected by cell viability and death assay, Western Blot, qRT‐PCR and immunofluorescence analysis.

Results

Phosphorylation of RIP3 and mixed lineage kinase domain‐like protein (MLKL) was increased in the periodontal ligament of mice infected with P. gingivalis. RIP3 knockdown reduced osteoclastogenesis and inflammatory cytokines in the periodontal area, and alleviated alveolar bone loss in vivo. In vitro, P. gingivalis‐LPS‐induced RIP3‐mediated necroptosis in L929 cells, and knockdown of RIP3 by siRNA decreased the expression of inflammatory cytokines.

Conclusion

RIP3‐mediated necroptosis is activated in periodontitis and blocking necroptosis alleviates disease progression, indicating that RIP3 may be a potential target for periodontitis treatment.
Audiovisual information of oral epithelial dysplasia: Quality, understandability and actionability
Authors: Alamoudi Waleed , Riordain Richeal Ni , Fedele Stefano , Porter Stephen
Published: July 2023

Objectives

Online information on oral epithelial dysplasia (OED) is insufficient and of low quality. While only written information has been previously assessed, this study aims to evaluate the content and quality of audiovisual (AV) online information about OED.

Methods

One hundred and twenty‐seven materials were initially considered using six key words across two search engines (YouTube and Google). Ultimately, 29 materials remained for the final assessment. These materials were then analysed for content, quality (DISCERN instrument, JAMA benchmarks), understandability and actionability.

Results

Most contents were scientific (n = 25), while three videos were educational, and one video was a personal experience with OED. On a scale of 1–5, the overall DISCERN score was (mean ± SD = 2.26 ± 0.79), suggesting poor quality of information. Regarding JAMA benchmarks, there was no single material that fulfilled or lacked all four benchmarks. The overall mean understandability score was 82% and the actionability mean score was significantly low at 29%.

Conclusion

Although the vast majority of AV materials on OED were primarily produced for scientific purposes, these materials could be helpful as resources for patient education. Keeping in mind, however, that the desired quality and essential patient information about OED available online remains largely poor and missing.
Evaluation of the antiwear‐ability/scratch‐resistance efficacy of makeup products by in vitro test method application
Authors: Jiang Yanwen , Xu Zhongmou , Qiu Yuchen , Chen Gang , Wang Sijing
Published: July 2023

Objective

The objective of this study is to propose a method for assessing the antiwear‐ability (AW) or surface scratch‐resistance (SR) efficacy of makeup products through in vitro experiments.

Materials and method

The method primarily involves measuring the change in weight as a means of evaluating the overall effectiveness. AW/SR effects are evaluated by applying a fixed amount of makeup product on artificial fake skin and comparing the weight difference after simulated friction/scratch.

Results

The in vitro results indicate that this method is easy to operate and yields repeatable data. It consistently reflects differences between samples when compared to clinical studies.

Conclusions

This method effectively compares the AW/SR effects of makeup products and demonstrates utility in evaluating product efficacy and difference. It holds great scientific and practical value.
Is the Banking and Financial System Changing the Social and Political Global Dimension?
Authors: Guerco Laura
Published: July 2023

This paper aims to demonstrate how banking and financial centres, which are not formal political decision-makers, are gaining a growing and significant role in the social and political dimension. By focusing on the contemporary dominance of banks and financial centres, as opposed to an unduly narrow focus on their vital role in the interactions between nations, this study contributes to the much-needed conversation about the influence of non-State players in the social and political dimension. The case studies of banks involved in State and inter-State policy will be analysed using the theoretical framework presented in this thesis. The case study of PNB Paribas, which was allegedly involved in the Sudan war in 2002, by influencing political decision-makers and, as a result, changing political outcomes, will receive the majority of attention.
Twisted GGP problems and conjectures
Authors: Gan Wee Teck , Gross Benedict H. , Prasad Dipendra
Published: July 2023

In a series of three earlier papers, we considered a family of restriction problems for classical groups (over local and global fields) and proposed precise answers to these problems using the local and global Langlands correspondence. These restriction problems were formulated in terms of a pair $W \subset V$ of orthogonal, Hermitian, symplectic, or skew-Hermitian spaces. In this paper, we consider a twisted variant of these conjectures in one particular case: that of a pair of skew-Hermitian spaces $W = V$.
Ñamiajapú dajãrãsa: la obra como promesa de reencuentro
Authors: Herrera Casilimas Juan Camilo
Published: July 2023

Ñamiajapú dajãrãsa es un proceso de creación artística, colaborativo e interdisciplinar, surgido en 2018, que aborda el fenómeno de migración juvenil indígena en el departamento del Vaupés, en la Amazonía colombiana. A través de un ejercicio de memoria emotiva y reflexiva que conjuga la escritura con el archivo audiovisual, se exponen tantoaspectos contextuales y metodológicos del proceso creativo como preguntas y sentires generados a lo largo de cuatro años de la experiencia. De esta manera, se aproxima al lector a una iniciativa cuyo interés principal es posibilitar el encuentro y la relación entre creadores habitantes de Mitú, Villavicencio y Bogotá, indígenas y no indígenas, en un territorio común donde la confrontación y el diálogo entre narrativas culturales y generacionales, lenguajes y saberes constituyen la materia de creación y dan sentido a la acción desde el arte.
Práticas artísticas colaborativas para empurrar o céu e respirar
Authors: Mallmann Kalinka Lorenci , Machado Oliveira Andreia , André Genecí Fidélis
Published: July 2023

O presente artigo, cujo título se utiliza da expressão de origem indígena brasileira “empurrar o céu”, se trata de uma reflexão teórica em torno da crise mundial, acentuada pelo evento da pandemia, e propõe pensarmos, a partir do âmbito da arte, de que modo podemos seguir adiante, melhores do que antes. A arte colaborativa/arte socialmente engajada e o papel do artista, nesse contexto, atuariam como alternativasde subversão da crise e transformação social? Desse modo, esse artigo aborda a arte como campo de fazeres e atuação, muito além dos discursos teóricos instaurados. Sendo assim, discorremos sobre a arte como terreno para a efetivação do fazer a partir do conceito de arte e vida de Alan Kaprow e das considerações em torno das práticas artísticas colaborativas contemporâneas. Ao longo desse estudopretendemos problematizar o conhecimento eurocêntrico, o qual opera de modo excludente, trazendo o pensamento de autores indígenas brasileiros como Ailton Krenak,Davi Kopenawa, Kaka Werá, Jaider Esbell; em diálogo com o filósofo chinês Yuk Hui e a socióloga indígena boliviana Silvia Rivera Cusicanqui. Ambos os autores, de origem não ocidental, tensionam e enriquecem o discurso em torno do Antropoceno.Esse texto também se utiliza de referências artísticas contemporâneas com povos indígenas brasileiros para refletirmos em novos caminhos fomentados por práticas colaborativas em arte e seus métodos horizontais. Dentre os apontamentos desse estudo, foi possível vislumbrar o campo artístico como potência para criar outras concepções teórico-práticas, rumo ao sentido de decolonização do conhecimento geral, apesar de toda recusa estrutural do sistema global.
New record of the predatory gall midge Feltiella acarisuga (Vallot) (Diptera: Cecidomviidae) preying on red tomato spider mite Tetranychus evansi Baker and Pritchard (Acari: Tetranychidae) in Guiyang, China
Authors: Feng Bing-Xia , Li Xue-Lin , Jiang Zhao-Chun , Fu Jun-Xian , Wang Liang , Xiao Feng , Yang Mao-Fa , Liu Jian-Feng
Published: July 2023

N/A
Synthesis of sound field from moving complex sources with arbitrary trajectories by linear and spherical loudspeaker arrays
Authors: Sasaki Yo , Matsui Kentaro , Nakayama Yasushige
Published: July 2023

The spectral division method (SDM) and near-field compensated higher order ambisonics (NFC-HOA) are sound field synthesis techniques based on the spatial Fourier representation of sound fields. Previous studies have derived the driving functions of SDM for sound field synthesis with consideration to uniformly moving point sources and moving point sources with arbitrary trajectories. However, the driving functions of NFC-HOA for synthesizing sound fields from moving sound sources have not been proposed to date. For a more realistic auditory experience, the synthesis of a sound field produced by a moving sound source with a complex radiation property is required. This study focused on deriving the driving functions for synthesizing sound fields produced by moving sound sources with arbitrary trajectories and radiation properties. Sound fields were formulated in the angular spectrum and spherical harmonic domains and applied to SDM and NFC-HOA, respectively. Numerical and measurement experiments were conducted to evaluate the proposed method. The results reveal that the proposed method can synthesize the desired sound fields.
Two year follow-up of distal unruptured intracranial aneurysms treated with a surface modified flow diverter under prasugrel monotherapy
Authors: de Castro-Afonso Luis Henrique , Machado João Paulo , Nakiri Guilherme Seizem , Abud Thiago Giansante , Monsignore Lucas Moretti , Freitas Rafael Kiyuze , de Oliveira Ricardo Santos , Colli Benedicto Oscar , Abud Daniel Giansante
Published: July 2023

Background

A new generation of modified surface flow diverters (FDs) and monotherapy using new antiplatelets may reduce both ischemic and hemorrhagic complications during the treatment of intracranial aneurysms. Previous preliminary safety analysis of distal unruptured intracranial aneurysms treated with the FD p48 MW HPC (phenox-Wallaby, Bochum, Germany) under antiplatelet monotherapy with prasugrel showed promising results. However, the long term outcomes of distal intracranial aneurysms treated with FDs under antiplatelet monotherapy are not known.

Methods

This was a single center, prospective, pivotal, open single arm study. The primary (safety) endpoint was absence of any new neurological deficits after treatment until the 24 month follow-up. The primary (efficacy) endpoint was the incidence of complete aneurysm occlusion 24 months after treatment. The secondary (efficacy) endpoints were any incidence of aneurysm dome reduction 24 months after treatment.

Results

21 patients harboring 27 distal aneurysms of the anterior circulation were included. No patient had neurologic deficits in the time from treatment to the 24 month follow-up. Complete aneurysm occlusion occurred in 20 (74%) of 27 aneurysms at the 24 month follow-up. Four aneurysms (14.8%) had dome reduction, and three aneurysms (11.1%) remained unchanged.

Conclusions

In this pilot trial, treatment of distal unruptured intracranial aneurysms with an FD under monotherapy with prasugrel, followed by monotherapy with aspirin, appeared to be safe and effective. Randomized studies with long term follow-up are needed to confirm these results.
Introgression of non-native mitochondrial haplotypes from farmed to wild Atlantic salmon
Authors: Wacker Sebastian , Bolstad Geir H. , Diserud Ola H. , Hindar Kjetil , Karlsson Sten
Published: July 2023

Farmed salmon escape and interbreed with wild Atlantic salmon on a large scale. We studied introgression of mitochondrial haplotypes from farmed Atlantic salmon originating from the Eastern Atlantic phylogenetic group to wild salmon of the Barents-White Sea (BWS) phylogenetic group. We find that farmed genetic introgression introduced novel, non-native haplotypes into the BWS phylogenetic group. The mitochondrial genome has important functional effects and is inherited as a haploid from the mother. Hence, the observed introgression across natural genetic barriers is expected to cause long-lasting functional maladaptation of the hybrids in the maternal line. As the use of farmed Atlantic salmon from non-native phylogenetic groups is widespread in aquaculture, the impact on wild Atlantic salmon may be more severe than previously recognized. Our results highlight the ecological risks of releasing non-native wild and domesticated animals.
Banking Crises in Historical Perspective
Authors: Frydman Carola , Xu Chenzi
Published: July 2023

This article surveys the recent empirical literature on historical banking crises, defined as events taking place before 1980. Advances in data collection and identification have provided new insights into the causes and consequences of crises both immediately and over the long run. We highlight three overarching threads that emerge from the literature: First, leverage in the financial system is a systematic precursor to crises; second, crises have sizable negative effects on the real economy; and third, government interventions can ameliorate these effects. Contrasting historical episodes reveals that the process of crisis formation and evolution varies significantly across time and space. Thus, we also highlight specific institutions, regulations, and historical contexts that give rise to these divergent experiences. We conclude by identifying important gaps in the literature and discussing avenues for future research.
Social Inequality in High Tech: How Gender, Race, and Ethnicity Structure the World's Most Powerful Industry
Authors: Neely Megan Tobias , Sheehan Patrick , Williams Christine L.
Published: July 2023

The high-tech industry is the world's most powerful and profitable industry, and it is almost entirely dominated by white, Asian American, and Asian men. This article reviews research on social inequality in the high-tech industry, focusing on gender and race/ethnicity. It begins with a discussion of alternative ways of defining the sector and an overview of its history and employment demographics. Next is an analysis of gendered and racialized pathways into high-paying jobs in the industry, followed by a review of research on workplace organization that emphasizes how sexism and racism are embedded inside the firm and beyond it, through the design of high-tech products and services. Finally, gender and racial disparities in attrition rates are discussed. The conclusion calls for future research on social inequality and the funding structure of the industry, age discrimination inside tech, effective diversity policies, and labor movement activism throughout the high-tech industry.
Life Satisfaction and Dental Visits in Adults Aged ≥50 Years and Living with Diabetes Mellitus: A Comparison between Urban and Rural Mexican
Authors: Pérez Alvaro García , Cuevas-González Juan Carlos , Gutierrez Teresa Villanueva
Published: July 2023

Objective. To examine the association between low life satisfaction with past‐year dental visits in a rural‐urban national sample of 50‐year‐old Mexican adults with diabetes mellitus (DM). Methods. Data are drawn from the Mexican Health and Aging Study (MHAS), a cross‐sectional study conducted in 2018 involving 3,592 older adults aged 50 years and older and living in urban and rural areas in Mexico. Life satisfaction was measured using the Satisfaction with Life Scale (SWLS) and past‐year dental visits dichotomized as none and ≥1 dental visits. The Poisson regression analyses were used to assess the association, adjusting for confounders. Results. 62.9% were women, mean age was 65.5 (±9.6), and 16.5% lived in a rural area, while the female subjects continue to present a higher probability of visiting a dentist (PR = 1.28 (95% CI 1.08–1.51)). In terms of age, the ≥70‐year group presented 28% lower possibility of visiting a dentist (PR = 0.72 (95% CI 0.60–0.86)). The interaction showed that adults ≥50 years who reside in a rural area and have low life satisfaction were 40% less likely to have visited a dentist in the last year (PR = 0.60 (95% CI 0.37–0.98)) than adults ≥50 years who reside in an urban area and have high life satisfaction. Conclusions. The present study highlights the association between low life satisfaction and past‐year dental visits in rural populations. Therefore, rurality should be considered a possible confounder in analysis of life satisfaction in the older adult population.
Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer
Authors: Mayoh Chelsea , Mao Jie , Xie Jinhan , Tax Gabor , Chow Shu-Oi , Cadiz Roxanne , Pazaky Karina , Barahona Paulette , Ajuyah Pamela , Trebilcock Peter , Malquori Angela , Gunther Kate , Avila Anica , Yun Doo Young , Alfred Stephanie , Gopalakrishnan Anjana , Kamili Alvin , Wong Marie , Cowley Mark J. , Jessop Sophie , Lau Loretta M.S. , Trahair Toby N. , Ziegler David S. , Fletcher Jamie I. , Gifford Andrew J. , Tsoli Maria , Marshall Glenn M. , Haber Michelle , Tyrrell Vanessa , Failes Timothy W. , Arndt Greg M. , Lock Richard B. , Ekert Paul G. , Dolman M. Emmy M.
Published: July 2023

Abstract
For one-third of patients with pediatric cancer enrolled in precision medicine programs, molecular profiling does not result in a therapeutic recommendation. To identify potential strategies for treating these high-risk pediatric patients, we performed in vitro screening of 125 patient-derived samples against a library of 126 anticancer drugs. Tumor cell expansion did not influence drug responses, and 82% of the screens on expanded tumor cells were completed while the patients were still under clinical care. High-throughput drug screening (HTS) confirmed known associations between activating genomic alterations in NTRK, BRAF, and ALK and responses to matching targeted drugs. The in vitro results were further validated in patient-derived xenograft models in vivo and were consistent with clinical responses in treated patients. In addition, effective combinations could be predicted by correlating sensitivity profiles between drugs. Furthermore, molecular integration with HTS identified biomarkers of sensitivity to WEE1 and MEK inhibition. Incorporating HTS into precision medicine programs is a powerful tool to accelerate the improved identification of effective biomarker-driven therapeutic strategies for treating high-risk pediatric cancers.
Significance:
Integrating HTS with molecular profiling is a powerful tool for expanding precision medicine to support drug treatment recommendations and broaden the therapeutic options available to high-risk pediatric cancers.
Neurocriptococose e Sarcoma de Kaposi associados à infecção por HIV: relato de caso.
Authors: Nascimento Milena Christine Krol do , Locastre Erich Giuliano , Reis Elise Souza dos Santos
Published: July 2023

A infecção pelo Vírus da Imunodeficiência humana (HIV) pode causar uma doença que é um importante problema de saúde pública em todo o mundo – a Síndrome da Imunodeficiência Adquirida (SIDA). Dentro das doenças definidoras da SIDA, há a infecção fúngica extrapulmonar pelo Cryptococcus spp e a neoplasia conhecida como Sarcoma de Kaposi. A Criptococose é uma micose sistêmica oportunista, cuja contaminação ocorre por inalação de propágulos viáveis do fundo e envolve    primariamente os pulmões. O fungo possui tropismo pelo sistema nervoso central, ocasionando a meningite criptocócica que é a forma clínica mais comum da doença, ocorrendo geralmente em condições de imunossupressão. Já o Sarcoma de Kaposi é causado pelo tipo 8 do herpes-vírus e é um tumor vascular frequentemente associado a pacientes HIV positivos. O presente trabalho tem por objetivo relatar um caso clínico de um paciente masculino, jovem, com diagnóstico recente de infecção pelo HIV, além de presença de Criptococose no sistema nervoso central e afecção dermatológica compatível com Sarcoma de Kaposi
Granulomatoses Nasais: relatos de casos e revisão de literatura direcionada diagnóstico
Authors: Gomes Mariana Ignacio , Lins Eliane Maria Dias von Söhsten , Dutra Marcela Giorisatto , Abreu Mariana Aguiar Bianco de , Abreu Carlos Eduardo Cesário de , Monteiro Edson
Published: July 2023

Introdução: As granulomatoses nasais são inflamações crônicas específicas que podem ser divididas conforme etiologia (infecciosa, desconhecida, induzida por trauma e autoimune). Por terem o poder de disseminação sistêmica representam um importante risco para a vida, sendo essencial um diagnóstico rápido e um adequado tratamento. Objetivo: Descrever 4 casos de granulomatoses nasais e realizar uma breve revisão sistemática focada no diagnóstico. Método: Os artigos foram obtidos utilizando-se as plataformas de busca MEDLINE e LILACS, no período dos últimos 5 anos (2017-2022) e nos idiomas português, inglês e espanhol. Os descritores utilizados para busca foram: “Nasal Tuberculosis Diagnosis”, “Histoplasmosis Nasal Diagnosis”, “Nasal Leishmaniasis Diagnosis” e “Eosinophilic Granulomatosis Polyangiitis Criteria Diagnoses”. Dentre os critérios de inclusão, permaneceram na análise apenas os artigos que tratavam da área nasal ou nasossinusal e que focavam no diagnóstico clínico e/ou laboratorial. Relato de casos: Quatro pacientes atendidos no período de fevereiro de 2019 a fevereiro de 2022, com diagnóstico de granulomatose nasal e tratados pelo serviço de Otorrinolaringologia do Hospital Santa Marcelina de Itaquera, São Paulo/SP, sendo um caso de granulomatose eosinofílica com poliangeíte (GEPA), um de tuberculose, um de histoplasmose e um de leishmaniose. Resultados: Dos 208 artigos encontrados, apenas 25 foram selecionados após avaliação. GEPA: O diagnóstico atualmente baseia-se nos critérios do Colégio Americano de Reumatologia 2022. Tuberculose: O diagnóstico pode ser feito através de achados histopatológicos. Histoplasmose: O padrão-ouro é o achado histopatológico do fungo utilizando-se a coloração com ácido periódico de Schiff (PAS). Leishmaniose: O método considerado padrão-ouro é a biópsia com detecção molecular do DNA do parasita pela PCR.Discussão: Houve uma boa correlação entre os métodos empregados pata o diagnostico desses casos e os sugeridos pelos artigos analisados. Conclusão: Embora infrequentes, as granulomatoses nasais geram muita morbidade, são de diagnóstico complexo e devem ser lembradas nos pacientes com inflamações nasais ou sinusais de difícil resolução com os tratamentos convencionais. Utilizando o roteiro diagnóstico descrito nessa breve revisão, acreditamos que seja possível uma melhora substancial na assertividade diagnostica.
Alternativas às transfusões de sangue utilizadas no transplante hepático em pacientes Testemunhas de Jeová: uma revisão integrativa
Authors: Costa Ana Clara Freitas Galvão Soares , Fonseca Neto Olival Cirilo Lucena da
Published: July 2023

Introdução: O transplante hepático (TxH) é uma intervenção cirúrgica com possibilidade de sangramento variável, no qual pode ser necessário a transfusão de hemocomponentes ou de sangue total. Contudo, pacientes Testemunhas de Jeová (TJ) conhecidamente não aceitam receber transfusões de sangue ou de hemocomponentes heterólogos, sendo necessário o uso de um gerenciamento diferenciado e utilização de terapias hemostáticas. Métodos: Foram selecionados artigos da base de dados PubMed no período de 1991 a novembro de 2022 com os descritores os descritores “Liver Transplantation in Jehovah's Witnesses”. Após uma leitura criteriosa, 16 artigos foram selecionados para esta revisão. Resultados: foram identificadas as terapias hemostáticas do pré-operatório (eritropoietina, ácido fólico, ferro), intraoperatórias (técnica de piggyback, hemodiluição normovolêmica aguda, Cell saver) e pós-operatórias (manutenção de terapias estimuladoras da eritropoiese). Conclusão: Considerando o importante papel de terapias transfusionais e hemostáticas no TxH e a necessidade de alternativas para os pacientes TJ, este estudo identificou as técnicas mais utilizadas nesses pacientes e demonstrou os benefícios individuais de cada uma.
Malefícios do uso do cigarro eletrônico para a cavidade oral e para a saúde sistêmica- Revisão Integrativa de Literatura
Authors: Oliveira Junior Julio Cezar de , Gomes Loren Carianne Rodrigues , Kamiyama Samira Yukaki , Araújo Ricardo Junio Vieira , Feitosa Maria Carolina de Negreiros , Morais Isabella Pereira , Duarte Felipe de Souza
Published: July 2023

O uso do cigarro eletrônico tornou-se popular nos últimos anos, havendo um aumento na venda e utilização por parte, principalmente, dos jovens e adolescentes. Essa prática trás diversos malefícios para esses usuários, como o desenvolvimento de doenças pré-cancerígenas em específico na cavidade bucal e na região de cabeça e pescoço. O objetivo do presente estudo foi realizar uma revisão integrativa da literatura publicada e indexada nos últimos anos entre o período de 2016 e 2023. Foram utilizadas as bases de dados do Pubmed e Biblioteca Virtual de Saúde (BVS), tendo sido buscados os termos “Eletronic-cigarrete and harmful effects and oral cavity” no Pubmed e os termos “Cigarro eletrônico e cavidade oral” na Biblioteca Virtual de Saúde. Após a aplicação dos critérios de inclusão e exclusão, foi realizada a leitura criteriosa e avaliação do conteúdo dos artigos, sendo incluídos 14 artigos em nosso trabalho. Os resultados demonstraram que as substâncias presentes no cigarro eletrônico são capazes de modular respostas inflamatórias e a expressão de citocinas e interleucinas relacionadas a processos patogênicos, comprometendo a resposta imune local de células da cavidade bucal. Conclui-se, portanto, que a utilização do cigarro eletrônico comprovadamente trás malefícios não somente para a cavidade oral, como também para a saúde sistêmica do indivíduo. Seu uso deve ser desencorajado através da promoção de saúde bucal e de orientações de profissionais do ramo odontológico.
Online Social Network Effects in Labor Markets: Evidence from Facebook's Entry to College Campuses
Authors: Armona Luis
Published: July 2023

Using quasi-random variation from Facebook's entry to college campuses, I exploit a natural experiment to estimate the effect of online social network access on future earnings. I estimate that access to Facebook for an additional year in college causes a .62 percentile increase in a cohort's average earnings, translating to an average wage increase of around $970 in 2014, and decreases income inequality within a cohort. I provide indirect evidence that wage increases come through the channel of increased social ties between college alumni, strengthened employment networks, and increased match value between students' majors and later occupations.