bluuebunny/crossref_metadata_2025 huggingface dataset:
The demographic profile of a patient with stroke
Authors:   Clinica 3, Institutul Naţional de Recuperare, Medicină Fizică şi Balneoclimatologie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Mitoiu Brînduşa Ilinca , Ojoga Florina ,   Clinica 3, Institutul Naţional de Recuperare, Medicină Fizică şi Balneoclimatologie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Nica Adriana Sarah ,   Clinica 3, Institutul Naţional de Recuperare, Medicină Fizică şi Balneoclimatologie, Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

Aim. Spastic hemiparesis is part of a complex clinical manifestation associated with a pathology of the central nervous system in a context of an ischemic or hemorrhagic stroke or in connection with various structural and functional innate or acquired changes. Disabling both the functional and psychosocial areas, spastic hemiparesis is a major element for the patient-centered concerns in the last decades. The study aims to create a demographic profile of a patient with stroke. Material and methods. The present study took into account patients hospitalized for clinical and functional assessment and specific rehabilitation program within a period of 6 months. It has aimed the collection of the demographic data including age, gender, living environment, education, as well as of the clinical data (age of the disease, comorbidities, smoker profile, features of the cerebral pathology, cognitive level). Results. The data were grouped to outline the profile of a hemiplegic patient addressed to our clinic for diagnosis and therapy. Discussions. A descriptive study of the group using data collected by direct interview or from medical documents was done. The limitations of the study are the difficulties in addressability especially for the patients that live in the rural areas and the lack of centralized data from other recent studies nationwide. Conclusion. The resulting data is very close to those shown in similar studies conducted in Europe and suggests the need for further development of health policies focusing on the needs of the neurological patients.
Influence of Mesocarp Fibre Inclusion on Thermal Properties of Foamed Concrete
Authors: Siti Shahirah Suhaili  , Md Azree Othuman Mydin  , Hanizam Awang
Published: September 2021

The addition of mesocarp fibre as a bio-composite material in foamed concrete can be well used in building components to provide energy efficiency in the buildings if the fibre could also offer excellent thermal properties to the foamed concrete. It has practical significance as making it a suitable material for building that can reduce heat gain through the envelope into the building thus improved the internal thermal comfort. Hence, the aim of the present study is to investigate the influence of different volume fractions of mesocarp fibre on thermal properties of foamed concrete. The mesocarp fibre was prepared with 10, 20, 30, 40, 50 and 60% by volume fraction and then incorporated into the 600, 1200 and 1800 kg/m3 density of foamed concrete with constant cement-sand ratio of 1:1.5 and water-cement ratio of 0.45. Hot disk thermal constant analyser was used to attain the thermal conductivity, thermal diffusivity and specific heat capacity of foamed concrete of various volume fractions and densities. From the experimental results, it had shown that addition of mesocarp fibre of 10-40% by volume fraction resulting in low thermal conductivity and specific heat capacity and high the thermal diffusivity of foamed concrete with 600 and 1800 kg/m3 density compared to the control mix while the optimum amount of mesocarp fibre only limit up to 30% by volume fraction for 1200 kg/m3 density compared to control mix. The results demonstrated a very high correlation between thermal conductivity, thermal diffusivity and specific heat capacity which R2 value more than 90%.
Hybrid Renewable Energy System for A Sustainable House-Power-Supply
Authors: Mohamed S. Emeara  , Ahmed Farouk AbdelGawad  , Emad Hamdy Ahmed
Published: September 2021

The main objective of the present research is to design a hybrid wind and solar energy-supply system for a rural residential building to meet its energy demands. The monthly averaged daily energy consumption for the dwelling was found to vary between 19 and 36 kWh. The system under consideration included some subsystems, namely: the hot-water service, the space-heating facility, and the power-utility system (wind electricity supply and storage system). The optimum design was obtained by carrying out a cost-benefit analysis for each of the subsystems. The hot-water system was designed to be based on solar flat-plate collectors, and a wind tree. The optimum hot-water facility is consisted of three flat-plate collectors, a storage heat exchanger with three coils, which are attached to flat-plate solar collectors, under-floor heating systems, and a wind tree power system. The large dimensions of the house were the limiting factor when investigating the feasibility of a solar-powered space-heating system. The existence of large windows made the space heating a very dif?cult and expensive task. The results show that the cost of the system is very expensive compared to the connection to the main grid. But on the other side, there will be a return investment value each year and the system will get all its costs after 14 years. Thus, if the average life of the system is 20 years old, the system will get profit after 14 years for six more years, in addition to the clean energy out from the system and the very beneficial positive effect on the environment.
Employer of Last Resort as a new ‘New Deal’: A few thoughts on Turkey
Authors: Aslan Ilker
Published: September 2021

Modern Monetary Theory emerges as a plausible alternative to solve Turkey’s staggering unemployment problem. This proposed solution here is the introduction of job guarantee program, which produces a non-discretionary automatic stabilizer that fosters both price stability and full employment. As a monetary sovereign, Turkey has the capacity to use deficit spending to bring growth and provide full employment to the millions who are in involuntary unemployment. The goal here is to tame the business cycles without throwing millions into unemployment, which has social and economic ramifications. In the absence of job creation by the private sector, this can be achieved through the use of government, providing job guarantees and the state acting as an employer of last resort by creating public projects, which will be cyclically adjusted in order to achieve full employment. 
The Youngest Planet to Have a Spin-Orbit Alignment Measurement AU Mic b
Authors: Addison Brett C. , Horner Jonathan , Wittenmyer Robert A. , Heitzmann Alexis , Plavchan Peter , Wright Duncan J. , Nicholson Belinda A. , Marshall Jonathan P. , Clark Jake T. , Günther Maximilian N. , Kane Stephen R. , Hirano Teruyuki , Wang Songhu , Kielkopf John , Shporer Avi , Tinney C. G. , Zhang Hui , Ballard Sarah , Bedding Timothy , Bowler Brendan P. , Mengel Matthew W. , Okumura Jack , Gaidos Eric , Wang Xian-Yu
Published: September 2021

We report measurements of the sky-projected spin–orbit angle for AU Mic b, a Neptune-size planet orbiting a very young (∼20 Myr) nearby pre-main-sequence M-dwarf star, which also hosts a bright, edge-on, debris disk. The planet was recently discovered from preliminary analysis of radial-velocity observations and confirmed to be transiting its host star from photometric data from the NASA’s TESS mission. We obtained radial-velocity measurements of AU Mic over the course of two partially observable transits and one full transit of planet b from high-resolution spectroscopic observations made with the Minerva-Australis telescope array. Only a marginal detection of the Rossiter–McLaughlin effect signal was obtained from the radial velocities, in part due to AU Mic being an extremely active star and the lack of full transit coverage plus sufficient out-of-transit baseline. As such, a precise determination of the obliquity for AU Mic b is not possible in this study and we find a sky-projected spin–orbit angle of

λ
=

47

−
54

+
26

°

. This result is consistent with both the planet’s orbit being aligned or highly misaligned with the spin axis of its host star. Our measurement independently agrees with, but is far less precise than observations carried out on other instruments around the same time that measure a low-obliquity orbit for the planet. AU Mic is the youngest exoplanetary system for which the projected spin–orbit angle has been measured, making it a key data point in the study of the formation and migration of exoplanets—particularly given that the system is also host to a bright debris disk.
Study of some risk factors for fungal contamination of dental unit waterlines in Alexandria, Egypt
Authors: Omran Eman Abdel Hamid , Abbass Aleya Abdel Gawad , Abaza Amani Farouk , Elzouki Eman Moftah
Published: September 2021

Introduction: Monitoring the microbial quality of water in dental unit waterlines is an important part of infection control measures carried out in dental clinics. Fungal contamination of such waterlines has not been extensively studied, compared with bacterial contamination. This study aimed at assessing the magnitude and risk factors for fungal contamination of dental unit waterlines.

Methodology: This cross-sectional study included 82 dental units, randomly collected from 3 private clinics and 8 governmental hospitals in Alexandria, Egypt. A total of 204 water samples from dental unit waterlines output were membrane-filtered and cultured for fungal enumeration and species identification. The biofilm forming-ability was assessed for the most prevalent fungal species. The acceptability of samples was determined according to the Swedish drinking water guidelines.

Results: The acceptability of samples was 89.7%. The most common mould was Aspergillus flavus, while Candida spp. was the most common yeast (10 isolates), with unusual predominance of Candida dubliniensis (9 isolates). All isolates of Aspergillus flavus and Candida dubliniensis were biofilm-formers. The risk factors for fungal contamination of dental unit waterlines included: dental specialty (p = 0.042), time of sample collection (p < 0.001), older age of dental unit (p < 0.001) and use of 5-15% of sodium hypochlorite.

Conclusions: The presence of biofilm-forming fungi in dental unit waterlines is a potential hazard, even when samples have acceptable levels of fungal counts. Risk factors for contamination are numerous and should be addressed.
Left Atrial Appendage Function Assessment by Tissue Doppler Transesophageal Echocardiography in Acute Ischemic Stroke Patients
Authors: Abdel Mawla Tamer , Momtaz Osama , Gayed Mohamed Abdel , Abdelrazek Gomaa
Published: September 2021

Background: Strokes due to Cardioembolic causes are the most severe in ischemic stroke subtypes. LAA flow patterns and function could be assessed accurately by TEE. The study aimed to present the importance of Transesophageal echocardiography in the assessment of LAA function and its relation to cardioembolic stroke. Methods: 120 patients were enrolled in the study and were subdivided into 3 subgroups, each group included 40 patients. Group A; patients had a stroke with normal sinus rhythm, Group B; patients had a stroke with atrial fibrillation, and Group C; normal control subjects. The study participants were evaluated by medical history, physical examination, standard 12-leads electrocardiogram, a transesophageal echocardiographic detailed evaluation of the LAA, and brain CT and/or MRI for patients with stroke. Results: both stroke patients with AF and sinus rhythm had significantly higher LAA mean orifice diameter and higher LAA length than control patients, significantly lower mean LAA medial wall tissue Doppler upward and downward motion velocities than control patients and that patients with stroke and AF had significantly lower mean LAA pulsed wave emptying and filling velocities than both patients with stroke and sinus rhythm and control patients. Presence of LAA thrombi, spontaneous echo contrast, and stroke recurrence were higher in stroked AF patients than stroke patients with sinus rhythm. Conclusion: increased LAA orifice diameter, LAA length, and reduced filling and emptying velocities and upward and downward motion velocities of the medial wall of LAA as detected by TEE are associated with stroke and cardio embolization.
An Image is Worth a Thousand Species: Scaling high-resolution plant biodiversity prediction to biome-level using citizen science data and remote sensing imagery
Authors: Gillespie Lauren , Ruffley Megan , Expósito-Alonso Moisés
Published: September 2021

Accurately mapping biodiversity at high resolution across ecosystems has been a historically difficult task. One major hurdle to accurate biodiversity modeling is that there is a power law relationship between the abundance of different types of species in an environment, with few species being relatively abundant while many species are more rare. This “commonness of rarity,” confounded with differential detectability of species, can lead to misestimations of where a species lives. To overcome these confounding factors, many biodiversity models employ species distribution models (SDMs) to predict the full extent of where a species lives, using observations of where a species has been found, correlated with environmental variables. Most SDMs use bioclimatic environmental variables as the dependent variable to predict a species’ range, but these approaches often rely on biased pseudo-absence generation methods and model species using coarse-grained bioclimatic variables with a useful resolution floor of 1 km-pixel.

Here, we pair iNaturalist citizen science plant observations from the Global Biodiversity Information Facility with RGB-Infrared aerial imagery from the National Aerial Imagery Program to develop a deep convolutional neural network model that can predict the presence of nearly 2,500 plant species across California. We utilize a state-of-the-art multilabel image recognition model from the computer vision community, paired with a cutting-edge multilabel classification loss, which leads to comparable or better accuracy to traditional SDM models, but at a resolution of 250m (Ben-Baruch et al. 2020, Ridnik et al. 2020). Furthermore, this deep convolutional model is able to accurately predict species presence across multiple biomes of California with good accuracy and can be used to build a plant biodiversity map across California with unparalleled accuracy. Given the widespread availability of citizen science observations and remote sensing imagery across the globe, this deep learning-enabled method could be deployed to automatically map biodiversity at large scales.
Semantic Search in Legacy Biodiversity Literature: Integrating data from different data infrastructures
Authors: Pachzelt Adrian , Kasperek Gerwin , Lücking Andy , Abrami Giuseppe , Driller Christine
Published: September 2021

Nowadays, obtaining information by entering queries into a web search engine is routine behaviour. With its search portal, the Specialised Information Service Biodiversity Research (BIOfid) adapts the exploration of legacy biodiversity literature and data extraction to current standards (Driller et al. 2020). In this presentation, we introduce the BIOfid search portal and its functionalities in a How-To short guide. To this end, we adapted a knowledge graph representation of our thematic focus of Central European, primarily German language, biodiversity literature of the 19th and 20th centuries. Now, users can search our text-mined corpus containing to date more than 8.700 full-text articles from 68 journals, and particularly focussing on birds, lepidopterans and vascular plants. The texts are automatically preprocessed by the Natural Language Processing provider TextImager (Hemati et al. 2016) and will be linked to various databases such as Wikidata, Wikipedia, the Global Biodiversity Information Facility (GBIF), Encyclopedia of Life (EoL), Geonames, the Integrated Authority File (GND) and WordNet. For data retrieval, users can filter search results and download the article metadata as well as text annotations and database links in JavaScript Object Notation (JSON) format. For example, literature that mentions taxa from certain decades or co-occurrences of species can be searched. Our search engine recognises scientific and vernacular taxon names based on the GBIF Backbone Taxonomy and offers search suggestions to support the user. The semantic network of the BIOfid search portal is also enriched with data from the EoL trait bank, so that trait data can be included in the search queries.

Thus, scientists can enhance their own data sets with the search results and feed them into the relevant biodiversity data repositories to sustainably expand the corresponding knowledge graphs with reliable data. Since BIOfid applies standard ontology terms, all data mobilized from literature can be combined with data on natural history collection objects or data from current research projects in order to generate more comprehensive knowledge. Furthermore, taxonomy, ecology and trait ontologies that have been built or extended within this project will be made available through appropriate platforms such as The Open Biological and Biomedical Ontology (OBO) Foundry and the Terminology Service of The German Federation for Biological Data (GFBio).
Effect of lisinopril therapy on serum leptin, oxidative stress and C-reactive protein in hypertensive patients
Authors: Althanoon Zeina A. , Mahmood Isam H.
Published: September 2021

The pathogenesis of essential hypertension through the interaction with elements of the rennin angiotensin aldosterone system is affected by oxidative stress and inflammation. The present study aimed to assess the effects of ACE-Inhibitor, lisinopril, on blood pressure, lipid profiles (total cholesterol, triglycerides, LDL and HDL), MDA, and TAS, hsCRP, and serum leptin levels n hypertensive patients. A case control study included 100 newly diagnosed mild to moderate hypertensive patients and another 100 apparently healthy aged and sex matched subjects as controls. The patients were treated with 10 mg lisinopril orally per day for three months’ duration. Venous blood sample was taken to test levels of MDA, GSH and TAS, hsCRP, lipid profiles and leptin in the serum before and after lisinopril therapy for both patients and controls. Systolic and diastolic blood pressure were also assessed before and after lisinopril therapy for both patients and controls. In hypertensive patients treated with lisinopril, markers of oxidative stress (MDA, TAS and GSH), high sensitive C-reactive protein and leptin were all found to be decreased significantly after drug treatment (p < 0.01). Lisinopril affectively lowered systolic and diastolic BP values (p < 0.01). A significant decrease in lipid profile (p < 0.01) with a significant increase in HDL-C and TAS levels (p < 0.01) were found in lisinopril treated group in comparison with their values before treatment. Lisinopril may be used as a treatment for high blood pressure, as well as for the insulin resistance, hyperleptinemic, and low-grade inflammatory states that are associated with the disease.
Scenopinus jerei, a new species of window fly (Diptera, Scenopinidae) from Finland
Authors: Pohjoismäki Jaakko , Haarto Antti
Published: September 2021

A new species of window fly (Diptera: Scenopinidae), Scenopinus jereisp. nov., with characteristic bicoloured legs and completely black halteres, is described from Finland. To exclude potential previously named species, a survey of the relevant type specimens as well as original descriptions of the Palearctic and Nearctic Scenopinus species has been conducted, including old Scenopinus fenestralis (Linnaeus) synonyms. Scenopinus jereisp. nov. is likely to be an overlooked, boreal forest specialist living in the nests of cavity-nesting birds. An identification key to the European species is provided.
Clinical Outcomes of a New Hybrid Monofocal IOL With Extended Depth of Focus
Authors: Baur Isabella D. , Khoramnia Ramin , Weindler Jan , Naujokaitis Tadas , Poompokawat Piyanut , Auffarth Gerd U.
Published: September 2021

PURPOSE:

To evaluate a new extended depth of focus intraocular lens (IOL), the xact Mono-EDOF ME4 (Santen Pharmaceuticals), Conformitè Europëenne–marked as a monofocal IOL, which has four diffractive rings intended to enhance intermediate vision.

METHODS:

Results are reported for 47 IOLs implanted in 28 patients who underwent cataract surgery and implantation of the xact Mono-EDOF ME4 IOL in one (9 patients) or both (19 patients) eyes. Postoperative follow-up examinations included visual acuity testing (monocular and binocular; uncorrected distance visual acuity [UDVA], corrected distance visual acuity [CDVA], uncorrected intermediate visual acuity [UIVA], distance-corrected intermediate visual acuity [DCIVA]), defocus curve and contrast sensitivity testing, and dysphotopsia evaluation.

RESULTS:

Follow-up at 6 months postoperatively revealed a monocular UDVA of 0.08 ± 0.15 logMAR, binocular UDVA of −0.02 ± 0.09 logMAR, monocular CDVA of −0.07 ± 0.08 logMAR, binocular CDVA of −0.09 ± 0.09 logMAR, monocular UIVA (70 cm) of 0.18 ± 0.16 logMAR, binocular UIVA (70 cm) of 0.09 ± 0.12 logMAR, monocular DCIVA (70 cm) of 0.25 ± 0.14 logMAR, and binocular DCIVA (70 cm) of 0.13 ± 0.11 logMAR. Defocus curve testing demonstrated a functional defocus of 1.25 diopters at 0.20 logMAR for monocular and 1.50 diopters at 0.20 logMAR for binocular testing. The contrast sensitivity corresponded to the age-appropriate normal values. Patients reported low levels of halo and glare.

CONCLUSIONS:

The xact Mono-EDOF ME4 IOL showed good functional results for far and intermediate distance visual acuity while inducing a low level of photic phenomena.

[
J Refract Surg
. 2021;37(9):601–608.]
Intraocular Povidone Iodine During Pars Plana Vitrectomy for Severe and Atypical Endophthalmitis
Authors: Mi Xiaofan , Malbin Brett , Lin Xihui
Published: September 2021

BACKGROUND AND OBJECTIVE:

To describe the experience and clinical outcomes of povidone iodine (PI) infusion in the setting of pars plana vitrectomy for the treatment of endophthalmitis.

MATERIALS AND METHODS:

This was a retrospective case series of 12 patients with clinical and/or culture evidence of endophthalmitis requiring pars plana vitrectomy with 0.025% PI used in vitreous irrigation solution during vitrectomy. The primary endpoint was clinical resolution of the infection. Secondary endpoints included visual recovery, need for repeat surgery, and ocular toxicity

RESULTS:

There were 11 eyes that showed clinical or culture evidence of resolution of infection postoperatively (91.7%); 10 eyes had improvement in vision postoperatively (83.3%). Overall uncorrected visual acuity improved from 20/5321 (2.43 ± 0.58 logMAR) to 20/375 (1.27 ± 1.05 logMAR) (
P
= .0003). No clinical evidence of ocular toxicity or unexplained vision loss due to PI was observed.

CONCLUSIONS:

PI infusion during pars plana vitrectomy for endophthalmitis appears safe and led to excellent post-surgical results in a traditionally high-risk cohort.

[
Ophthalmic Surg Lasers Imaging Retina.
2021;52:485–490.]
Modeling the trajectory of motion of a linear dynamic system with multi-point conditions
Authors: Petrovna ZUBOVA Svetlana ,   Faculty of Mathematics, Voronezh State University, Voronezh, Russia, Alexandrovich RAETSKIY Kirill
Published: September 2021

The motion of the linear dynamic system with given properties is modeled; conditions for system state at various arbitrarily points in time are given. Simulated movement carried out due to the calculated input vector function. The method of undefined coefficients is used to construct the input vector function and the corresponding trajectory. The proposed method consists in the formation of the state vector function, the trajectory of motion and the input vector function in exponential-polynomial form, that is, in the form of linear combinations of the powers of the time parameter with vector coefficients. This linear combination is complemented by a scalar exponential function with an additional parameter in the exponent to change the type of trajectory. To find the introduced coefficients, formulas and a linear algebraic system are formed. To find the introduced coefficients, the formed linear combinations are substituted directly into the equations describing the dynamic system and into the given multipoint conditions for finding the entered coefficients. All this leads to obtaining algebraic formulas and linear algebraic systems. Only the matrices included in the system that describe the dynamics of the model (and similar matrices with higher exponents) are the coefficients for the unknown parameters of the resulting algebraic system. It is proved that the fulfillment of the condition Kalman is sufficient for the solvability of the resulting system. To substantiate the solvability of the system, the properties of finite-dimensional mappings are used: decomposition of spaces into subspaces, projectors on subspaces, semi-inverse operators. But for the practical use of the proposed method, it is sufficient to solve the obtained linear algebraic system and use the obtained linear formulas. The correctness of the obtained model is investigated. Due to the non-uniqueness of the solution to the problem posed, the trajectory of motion can be unstable. It is revealed which components of the desired coefficients are arbitrary. It is showed which ones to choose, to make the movement steady, that is, so that small changes in the given multi-point values, as well as a small change parameters of the dynamic system corresponded to a small change in the trajectory of motion. An example is given of constructing trajectories of a material point in a vertical plane under the action of a reactive force in order to hit a given point with a given speed.
HPLC-MS identification and expression of Candida drug-resistance proteins from African HIV-infected patients
Authors: Abrantes Pedro M D S ,   Maternal Endogenous Infections Studies (MEnIS) Research Laboratories, Department of Medical Biosciences, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa, Fisher Randall , Bouic Patrick J D , McArthur Carole P , Fielding Burtram C , Africa Charlene W J ,   Separated Sector Cyclotron Laboratory, iThemba LABS, Radiation Biophysics Division, National Research Foundation, Cape Town, South Africa,   Synexa Life Sciences, PO Box 36596, Chempet 7442, South Africa,   Department of Oral and Craniofacial Sciences, School of Dentistry, University of Missouri-Kansas City, MO 64108, USA,   Molecular Biology and Virology Laboratory, Department of Medical Biosciences, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa
Published: September 2021

The objective of this study was to elucidate the proteomic mechanisms of drug resistance in HIV-infected African patients. Cell membrane fractions from forty oral Candida isolates isolated from African HIV-positive patients were analysed using HPLC-MS with the aim of identifying proteins associated with their pathogenicity and drug resistance. Heat shock proteins that mediate the fungicidal activity of salivary peptides were found in all tested Candida fractions, with pH-responsive proteins associated with increased pathogenicity only being present in the three most commonly isolated species. ABC multidrug transporter efflux pumps and estrogen binding proteins were only found in C. albicans fractions, while ergosterol biosynthesis proteins were identified in four species. The combination of various adherence, invasion, upregulation and efflux pump mechanisms appear to be instrumental for the Candida host colonization and drug resistance emergence in HIV-infected individuals.
Fall of Monuments as a Tool for Social Change
Authors: Wijegoonawardana N.
Published: September 2021

This paper will explore a different form of global socio-political protest, which spread in cities worldwide and was characterized by the pulling down of certain monuments in public space. This investigates how the fall of monuments operates as a tool for political resistance against marginalization, discrimination and exclusion, a binding factor for democracy and social justice, and as a means of dealing with contested heritage. Protesters referring to themselves as ‘Fallist,’ common across the world, raise concerns about race, identity, position and recognition in society. They choose pulling down monuments as a tool through which they demand addressing of socio-political injustices. In consideration of the above this study employs the methodological application of qualitative exploratory design as well as analyzing contemporary cases of street protest surrounding the pulling down of monuments from different geographic and socio -political contexts, including South Africa, United States and the United Kingdom. This paper further argues that the pulling down of monuments is thus not merely about contesting the past; it also operates as a tool for inquiring, critiquing, and changing the present.
Histone Deacetylase as a Valuable Predictive Biomarker and Therapeutic Target in Immunotherapy for Non-Small Cell Lung Cancer
Authors: Shin Hyun-Seock , Choi Juwhan , Lee Jinhwan , Lee Sung Yong
Published: September 2021

Purpose Histone deacetylase inhibitors (HDACis) are epigenetic regulators and used clinically for hematopoietic malignancies. Recently, HDACis have received attention as a factor that modulates the immune system. In this study, the role of histone deacetylase (HDAC) expression as a predictive marker in lung cancer patients who were treated with immune checkpoint inhibitors (ICIs) and the role of HDACi and ICI combination treatment in the mouse tumor model were analyzed.Materials and Methods The overall response rate (ORR) and progression-free survival (PFS) were analyzed by the expression of HDAC. In vitro assay, the mRNA and protein expression levels of cytokines and programmed death-ligand 1 (PD-L1) were analyzed after HDACi treatment. In vivo assay, TC-1 tumor-bearing mice were treated with HDACi and mouse programmed cell death 1 (PD-1) inhibitor.Results The HDAC6 low expression group showed high ORR and prolonged PFS. When the selective HDAC6 inhibitor was administered to the A549 cell line, the levels of interleukin-1β and interleukin-6 decreased and the expression of PD-L1 was reduced. Mice that received both the mouse PD-1 inhibitor and pan-HDACi had a smaller tumor size than that of the mice from the control group. Moreover, mice treated with the mouse PD-1 inhibitor and pan-HDACi generated greater numbers of E7-specific CD8+ T cells.Conclusion HDAC6 expression can predict the prognosis of non–small cell lung cancerpatients who were treated with ICIs. Furthermore, co-treatment with HDACi and PD-1 inhibitor was shown to decrease the tumor growth rate and create a favorable tumor microenvironment for cytotoxic T lymphocytes in the TC-1 mouse model.
The Allison–Faulkner construction of
Authors: Petrov Victor , Rigby Simon W.
Published: September 2021

We show that the Tits index$E_{8,1}^{133}$cannot be obtained by means of the Tits construction over a field with no odd degree extensions. The proof uses a general method coming from the theory of symmetric spaces. We construct two cohomological invariants, in degrees$6$and$8$, of the Tits construction and the more symmetric Allison–Faulkner construction of Lie algebras of type$E_8$and show that these invariants can be used to detect the isotropy rank.
Dancing with the Fan
Authors: Visočnik Gerželj Nataša
Published: September 2021

The article addresses several issues concerning a Japanese fan and the kimonos found in the collection of Ivan Skušek from Slovene Ethnographic Museum. They belonged to Ivan Skušek’s Japanese wife Marija Tsuneko Skušek, and were after her death donated to the museum together with other objects from the Skušek collection. With analysing these items and researching the life of Marija Tsuneko Skušek the article discusses the roles these objects had in transmitting Japanese culture to Slovene audience with a focus on the Japanese dances as one way of transmission. During her life in Ljubljana, Marija Skušek in one way adopted to the Slovene society very quickly, but on the other hand she presented Japanese culture and her identity in several lectures along with Japanese songs, dances and a tea ceremony. With researching the roles and values of these object in the museum collection, the article also discusses the importance of understanding not only the physical appearance of the items and their life, but also the wider background of items and collection, focusing also on the owner of these items in the relation to the collector. It is also important to stress how these objects transformed from daily objects of use to rarefied art after they were handed over to the museum, and within this process their value also changed.
The Food, Water, Air and Fire Doctrines in Ancient Indian and Greek Philosophies from a Comparative Perspective
Authors: Škof Lenart
Published: September 2021

The main aim of this article lies in the comparison of ancient cosmico-natural elements from the Vedic period with their counterparts in the Presocratics, with a focus on food, air, water and fire. By way of an introduction to the ancient elemental world, we first present the concept of food (anna) as an idiosyncratic Vedic teaching of the ancient elements. This is followed by our first comparison—of Raikva’s natural philosophy of Vāyu/prāṇa with Anaximenes’s pneûma/aér teaching in the broader context of both the Vedic and Presocratic teachings on the role of air/breath. Secondly, water as brought to us in pañcāgnividyā teaching from Bṛhadāraṇyaka Upaniṣad and Chāndogya Upaniṣad is compared to the teaching of the Greek natural philosopher Thales. Finally, the teaching on fire as heat being present in all beings (agni vaiśvānara) and in relation to cosmic teachings on fire in the ancient Vedic world are compared to Heraclitus’ philosophy of fire as an element. Additionally, this article also presents a survey and analysis of some of the key representatives of comparative and intercultural philosophy dealing with the elemental and natural philosophy of ancient India and Greece.
Between Ethnology and Cultural History
Authors: Vampelj Suhadolnik Nataša
Published: September 2021

While a few larger collections of objects of East Asian origin entered Slovenian mu­seums after the deaths of their owners in the 1950s and 60s, individual items had begun finding their way there as early as the nineteenth century. Museums were faced early on with the problem not only of how to store and exhibit the objects, but also how to categorize them. Were they to be treated as “art” on account of their aesthetic value or did they belong, rather, to the field of “ethnography” or “anthropology” because they could illustrate the way of life of other peoples? Above all, in which museums were these objects to be housed?
The present paper offers an in-depth analysis of these and related questions, seeking to shed light on how East Asian objects have been showcased in Slovenia (with a focus on the National Museum and the Slovene Ethnographic Museum) over the past two hundred years. In particular, it explores the values and criteria that were applied when placing these objects into individual categories. In contrast to the conceptual shift from “ethnology” to the “decorative and fine arts,” which can mostly be observed in the categorization of East Asian objects in North America and the former European colonial countries, the classification of such objects in Slovenia varied between “ethnology” and “cultural history,” with ethnology ultimately coming out on top. This ties in with the more general question of how (East) Asian cultures were understood and perceived in Slovenia, which is itself related to the historical and social development of the “peripheral” Slovenian area compared with former major imperial centres.
Romanian Horse Names
Authors: Pușcaș Andreea-Nora
Published: September 2021

The present study focuses on identifying and classifying the equine zoonyms used in recent years in Romania, with the purpose of identifying the language trend and, if possible, what stands behind the motivation of onymic units. In addition, a comparison with the results of another study undertaken by us will be made, more specifically, a paper dealing with horse names extracted from the first survey (The Horse) issued by The Museum of the Romanian Language in 1922. The current study aims to identify the changes this onomastic segment was subject to.
Lessico medico italiano e polacco a confronto: il caso dei sintagmi terminologici di tipo malattia di Banti/choroba Bantiego
Authors: Dyda Anna , Pronińska Aleksandra
Published: September 2021

Contrastive analysis of Italian and Polish medical vocabulary: case of terminological syntagms such as malattia di Banti/choroba Bantiego

The main objective of this paper is to analyze medical terminology based on eponyms in Italian and Polish languages. The study is divided into an introduction, five sections and a conclusion. In the first part of the paper, the subject was introduced by determining the definitions of certain elements presented in the study, namely eponyms, synonyms and variants. In the following parts of the article, we proceed with the intralinguistic and interlinguistic analysis of eponymic terms. On the intralinguistic level, we have analyzed the eponymic terms in Italian as well as the co-presence of the other terms in medical language, while for interlinguistic analysis we have observed how medical terms with Italian onomastic component are used in the Polish language.
L’altérité, la culture et l’interculturel dans l’ouvrage L’altérité en classe de langue. Pour une méthodologie éducative de Jean-Claude Beacco
Authors: Pudo Dorota
Published: September 2021

Alterity, Culture and Interculturality in the book L’altérité en classe de langue. Pour une méthodologie éducative by Jean-Claude Beacco The article discusses the book L’altérité en classe de langue. Pour une méthodologie éducative by Jean-Claude Beacco. This work, proposing an innovative way of treating alterity in a foreign language classroom, adopts a critical stance toward earlier “intercultural” approaches and proposes a coherent, innovative and systematic pedagogical methodology.
Phân tích hiệu quả kỹ thuật của nông hộ nuôi tôm sú thâm canh tại Thị xã Giá Rai, Tỉnh Bạc Liêu
Authors: Duyên Thi Thị Mỹ
Published: September 2021

Bài nghiên cứu nhằm mục đích đo lường hiệu quả kỹ thuật và xác định các yếu tố quyết định hiệu quả kỹ thuật sản xuất tôm sú thâm canh của nông hộ tại thị xã Giá Rai, tỉnh Bạc Liêu. Dựa vào kết quả khảo sát 44 nông hộ nuôi tôm sú thâm canh trên địa bàn thị xã Giá Rai, nghiên cứu sử dụng phương pháp phân tích màng bao dữ liệu (DEA) để đo lường hiệu quả kỹ thuật và hiệu quả theo quy mô. Kết quả cho thấy, hiệu quả kỹ thuật trung bình và hiệu quả quy mô trung bình của các hộ nuôi tôm sú thâm canh lần lượt là 59% và 79.9%. Kết quả của mô hình Tobit cho thấy có ba yếu tố có tác động tích cực đến hiệu quả kỹ thuật của hộ nuôi, bao gồm trình độ học vấn, mật độ giống và xét nghiệm.
Yếu tố ảnh hưởng đến việc áp dụng VietGAP của hộ trồng xoài ở Đồng bằng sông Cửu Long
Authors: Nhân Trần Quốc , Phúc Lương Hoàng , Nay Nguyễn Văn , Dễ Lê Văn
Published: September 2021

Nghiên cứu nhằm xác định các yếu tố ảnh hưởng đến việc chấp nhận áp dụng tiêu chuẩn VietGAP vào sản xuất xoài của nông hộ ở Đồng Bằng Sông Cửu Long (ĐBSCL). Số liệu sử dụng cho nghiên cứu được thu thập từ 110 hộ sản xuất xoài, trong đó 49 hộ sản xuất theo quy chuẩn VietGAP và 61 hộ sản xuất tự do tại tỉnh Hậu Giang và Sóc Trăng. Mô hình hồi qui nhị phân (logit) được sử dụng chủ yếu trong nghiên cứu để phân tích số liệu. Kết quả nghiên cứu cho thấy nếu nông hộ có tham gia vào các tổ chức nông dân, tần suất tiếp cận Cán Bộ Khuyến Nông (CBKN) nhiều và hộ có có tiếp cận với Internet sẽ có xu hướng chấp nhận áp dụng quy chuẩn VietGAP vào sản xuất xoài. Trong khi đó, trình độ học vấn chủ hộ càng cao thì hộ ít có xu hướng áp dụng VietGAP.
Các nhân tố ảnh hưởng đến ý định dự thi chứng chỉ Kế toán viên và Kiểm toán viên - Nghiên cứu thực nghiệm tại Cần Thơ
Authors: An Nguyễn Thúy , Hương Lê Phước , Phương Huỳnh Nhựt
Published: September 2021

Nghiên cứu nhằm đánh giá các nhân tố ảnh hưởng đến ý định tham dự thi lấy chứng chỉ kế toán viên và kiểm toán viên (Certified Public Accountant - CPA) của Việt Nam đối với cá nhân có chuyên ngành bậc đại học là kế toán và kiểm toán trên địa bàn thành phố Cần Thơ. Nghiên cứu này dựa trên thuyết hành vi hợp lý (Theory of Reasoned Action - TRA) và thuyết dự định hành vi (Theory of Planned Behaviour - TPB) để xây dựng mô hình nghiên cứu. Dữ liệu được thu thập bằng cách phỏng vấn 400 đáp viên thông qua bảng câu hỏi. Sử dụng phân tích nhân tố khám phá EFA, phân tích nhân tố khẳng định CFA và mô hình cấu trúc tuyến tính SEM, nghiên cứu đã cho thấy có mối quan hệ thuận chiều của quy định liên quan kỳ thi, quan điểm cá nhân về nghề nghiệp, yếu tố kỳ vọng và thái độ đối với việc dự thi, tiếp theo đó, thái độ dự thi lấy chứng chỉ và sự hỗ trợ từ trường đại học đào tạo ngành có mối quan hệ thuận chiều với ý định dự thi. Từ đó, nghiên cứu đề xuất một số giải pháp để thúc đẩy ý định dự thi của những cá nhân phù hợp với chuyên ngành đào tạo, và các hướng nghiên cứu tiếp theo để xác định các nhân tố thúc đẩy từ ý định đến quyết định dự thi lấy chứng chỉ CPA Việt Nam.
Perancangan Dan Pembuatan Company Profile Berbasis Website Sebagai MEdia Promosi Dan Informasi Pada Sekolah Tinggi Teologia Ekklesia Pontianak
Authors: Firgia Listra , Nurcahyo Azriel Christian
Published: September 2021

Sekolah Tinggi Teologia Ekklesia Pontianak salah satu Perguruan Tinggi Swasta yang berada di Pontianak. Dalam mempromosikan STT Ekklesia ke masyarakat masih menggunakan konvensional seperti brosur, flyer, dan spanduk. Tujuan dari penelitian ini adalah merancang dan membuat website sebagai media promosi. Sekolah Tinggi Teologi Ekklesia Pontianak bisa memanfaatkan website sebagai media promosi untuk menunjukan bahwa Sekolah Tinggi Teologia Ekklesia Pontianak tersebut memiliki alternatif untuk mempromosikan kampusnya. Pada penelitian ini menggunakan HTML, CSS dan JavaScript untuk pembuatan website dan memiliki kriteria website yang menarik, rapi dan isi konten yang dapat dimengerti sehingga masyarakat dapat melihat website tersebut menggunakan media handphone, laptop yang sudah mempunyai tampilan halaman website yang sesuai dengan device. Metode yang digunakan dalam penelitian ini yaitu wawancara dan observasi. Hasil yang telah dilakukan dengan merancang, membuat dan implementasi website sebagai media promosi, diharapkan akan meningkatkan kualitas baik itu fasilitas, tenaga pengajar dan sebagainya untuk dapat bersaing dengan Sekolah Tinggi lainnya.

Kata Kunci— School, website, promosi, informasi, company profile
Sistem Pengelolaan Data Pesanan dan Servis Jok Berbasis Web Menggunakan Metode RAD
Authors: Rahmat Robi Waliyansyah  , Supratiyan Edi Dwi , Harjanta Aris Tri Jaka
Published: September 2021

Toko Romeo Jok adalah toko mebel yang menjual berbagai jenis mebel dan menyediakan jasa servis segala jenis mebel yang berada di Kabupaten Pati. Toko Romeo Jok masih menggunakan pendataan data pesanan dan servis secara manual maka terjadi masalah kurang terorganisirnya data pesanan dan servis, dan data mudah untuk hilang. Sehingga diperlukan sebuah sistem pengelolaan data yang dapat menyimpan dan menyajikan data pesanan dan servis secara akurat, efektif, dan efisien. Pembangunan sistem pengelolaan data pesanan dan servis berbasis web ini bisa digunakan Toko Romeo Jok untuk mengelola data pesanan dan servis secara cepat, mudah, dan akurat. Pada tahap perancangan sistem ini memgunakan metode pengembangan Rapid Application Development (RAD), yaitu metode yang menyediakan pengembangan yang cepat dan mendapatkan hasil yang bagus . Sistem pengelolaan data pesanan dan servis jok berbasis web ini di buat menggunakan bahasa pemograman PHP dan mengunakan software xampp dan text editor seperti sublime text, pembuatan desain sistem menggunkan draw.io, basis data nya menggunakan MySQL. Berdasarkan Hasil UAT dari aspek penilaian antar muka mendapat persentase 82% dari aspek penilaian kemudahan pengoperasional mendapatkan presentase 84% dan dari aspek kemanfaatan isi sistem ini mendapat persentase 83%. Sistem ini terbukti layak digunakan karena pada hasil pengujian white box dan black box keduanya mendapat hasil persentase 100%.
Analisis Potensi Daerah Rawan Longsor di Kecamatan Bawen dan Tuntang dengan Metode Simple Additive Weighting (SAW)
Authors: Mira  , Lestari Merryana , Gudiato Candra , Prasetyo Sri Yulianto , Fibriani Charitas
Published: September 2021

Intensitas curah hujan yang tinggi pada penghujung tahun 2020 dan awal tahun 2021 tidak hanya menyebabkan beberapa daerah di Indonesia terendam banjir, namun juga tanah longsor. Tanah Longsor dapat terjadi karena adanya pergerakan tanah di musim penghujan serta dipengaruhi kondisi tektonik di Indonesia yang selalu berubah-ubah. Kecamatan Bawen dan Tuntang adalah dua Kecamatan yang berada di Kabupaten Semarang, Jawa Tengah. Kedua daerah tersebut dilanda bencana banjir dan tanah longsor pada April 2020 silam. Kerugian materiil dan moril dari penduduk setempat tentunya tidak dapat dihindari. Untuk melakukan pencegahan sedini mungkin agar dapat menekan kerugian di masa mendatang, perlu dilakukan penelitian mengenai potensi daerah-daerah yang rawan longsor di Kecamatan Bawen dan Tuntang. Analisis yang dilakukan menggunakan metode Simple Additive Weighting (SAW) untuk menghitung persentase suatu daerah terjadi longsor. Adapun parameter yang digunakan antara lain tutupan lahan, kemiringan kelerengan, curah hujan, Soil Adjusted Vegetation Index (SAVI), Normalized Difference Vegetation Index (NDVI), dan Normalized Difference Wetness Index (NDWI). Hasil dari penelitian ini menunjukkan bahwa  tingkat kerawanan bencana tanah longsor di Kecamatan Bawen dan Tuntang tergolong “kurang rawan”. Hasil dari penelitian ini diharapkan dapat menjadi dokumen perencanaan tata ruang berbasis mitigasi bencana tanah longsor di Kabupaten Semarang, khususnya pada Kecamatan Bawen dan Tuntang.
Mathematical Modeling of Heat and Mass Transfer in Heat Pipes in a One-Dimensional Formulation when Cooling Active Phased Antenna Arrays
Authors: Radaev S.
Published: September 2021

The work proposes test one-dimensional models of heat and mass transfer in heat pipes during cooling of active phased antenna arrays, which can be used in processing the test results of flat heat pipes in order to determine their performance characteristics and identify the parameters required for modeling in a more complex setting (for example, in flat and taking into account the presence of several localized sources of heat supply). To take into account the influence of the heat release power on the equilibrium temperature inside the heat pipe, the model has been added to take into account the dependence of the steam saturation temperature on the pressure, which is realized inside the steam pipeline when the heat pipe is heated. Numerous calculations carried out made it possible to refine the mathematical model. In particular, a significant effect on the temperature distribution along the heat pipe is shown, taking into account the dependence of the steam saturation temperature on the pressure in the parawire. It is shown that the introduction of standard functions for the characteristics of the coolant (water) in the liquid and vapor state, as well as taking into account the capillary pressure on temperature, makes it possible to refine the resulting solution.