bluuebunny/crossref_metadata_2025 huggingface dataset:
Müzik Performans Kaygısı Alanında Yapılan Araştırmaların Türkiye Ölçeğinde İncelenmesi
Authors: KURTASLAN Zafer , SARIKAYA Muhsin , DÖNMEZ Ender Can , KİBİCİ Volkan Burak
Published: September 2022

Bu araştırmanın amacı, Türkiye genelinde geçmişten günümüze, müzikal performans kaygısı alanında yapılmış olan tez ve araştırma makalelerinin incelenmesidir. Bu amaçla, araştırmada kullanılan veriler YÖK Ulusal Tez Merkezi, Dergi Park, TR Dizin ve Google Akademik veri tabanları kullanılarak alan yazın taraması ile elde edilmiştir. Alan yazın taraması sonucunda farklı düzeylerde yirmi beş tez ve yirmi makaleye ulaşılmıştır. Tez ve araştırma makaleleri yapıldıkları üniversite, yıl, düzey, yöntem ve teknikler bakımından içerik analizine tabi tutulmuştur. Bulgulardan elde edilen sonuçlar, müzikal performans kaygısı alanında 2009 yılından günümüze yapılan yirmi beş tezin yarısından fazlasının yüksek lisans düzeyinde olduğunu, yirmi dört üniversitede birer tez yapılırken Marmara Üniversitesinde altı tezin yapıldığını göstermiştir. Ayrıca, tezlerin çok yüksek oranda nicel araştırma desenleri kullanılarak gerçekleştirildiği sonucuna ulaşılmıştır. Bununla birlikte, müzikal performans kaygısı alanında 2012 yılından günümüze yazılan yirmi araştırma makalesinin tamamına yakınının nicel araştırma yöntemi ve derleme türünde oluşturulduğu sonucuna ulaşılmıştır. 1988-2021 yılları arasında yapılan üç bine yakın tez ve çok sayıda araştırma makalesi içerisinde müzikal performans kaygısı ile ilgili sadece yirmi beş tezin olması ve çok az sayıda makale üretilmesine dikkat çekilmiştir. Ayrıca Türkiye'deki araştırmalarda ağırlıklı olarak müzik performans kaygısının tek değişkenli ve boyutlu olarak ele alındığı ve çalışmaların tarama modeliyle gerçekleştirildiği gözlenmiştir.
Реалізація першого етапу модернізації однорядних контейнерних збірок зі зразками-свідками металу корпусу реактора ВВЕР-1000 енергоблока № 1 Південноукраїнської АЕС
Authors: Grytsenko O. , Bukanov V. , Diemokhin V. , Pugach O. , Vasylieva O. , Revka V. , Chyrko L. , Trygubenko O. , Chaikovskyi Yu.
Published: September 2022

Необхідною умовою експлуатації реактора ВВЕР-1000 є контроль стану металу корпусу протягом усього строку служби. Штатна програма зразків-свідків дає змогу контролювати стан його корпусу тільки протягом проєктного строку експлуатації. Тому, з метою забезпечення матеріалознавчого супроводу експлуатації корпусу в понадпроєктний період розроблено програми модернізації однорядних контейнерних збірок зі зразками-свідками металу корпусів реакторів ВВЕР-1000 АЕС України.

Суть модернізації полягає в перенесенні контейнерів зі зразками-свідками на рівень нижнього ряду штатної дворядної збірки з поворотом на 180º. Так забезпечується випереджаюче приблизно в 2,5 раза порівняно з корпусом опромінення зразків-свідків та вирівнювання флюенсів швидких нейтронів між зразками з метою підбору представницьких груп для випробувань.

Першим етапом програми модернізації однорядних контейнерних збірок реактора енергоблока № 1 Південноукраїнської АЕС передбачено модернізацію збірки 5Л2 зі зразками металу шва № 3. Її було вивантажено після 28-ї паливної кампанії, модернізовано та повернуто в реактор після 29-ї кампанії. Крім того, в межах проведення дозиметричного експерименту з метою дослідження характеристик поля нейтронів у місцях розташування зразків-свідків штатної програми в реактор було завантажено три метрологічні збірки з розширеним набором індикаторів нейтронного потоку.

Після закінчення 35-ї паливної кампанії модернізовану збірку 5Л2 було вивантажено з реактора й доправлено в Інститут ядерних досліджень Національної академії наук України, де її було розібрано та визначено флюенси швидких нейтронів, накопичені кожним зразком. Крім того, ґрунтуючись зокрема на даних дозиметричного експерименту оцінено похибки визначення флюенсів.

Після опромінення модернізованої контейнерної збірки було отримано 12 штатних зразків Шарпі з близькими флюенсами, що значно перевищують флюенс на корпус. Це, зі свого боку, дозволило провести їх випробування на ударний вигин з дотриманням усіх вимог нормативних документів та виконати достовірну оцінку зсуву критичної температури крихкості металу шва № 3 корпусу реактора енергоблока № 1 Південноукраїнської АЕС у понадпроєктний період його експлуатації.
Parametric Analysis of Correlation Functions for Acoustic Monitoring and Assessment of Underground Piping at NPPs
Authors: Vladimirsky А. , Vladimirsky I. , Dybach O.
Published: September 2022

Monitoring and assessment of the technical condition of underground pipelines of process systems important to safety is a relevant task of the ageing management process for existing NPPs. Methods applied in other industries having underground pipelines (oil/gas/public utilities) could be considered. The paper is devoted to theoretical issues of overcoming the interfering redundancy contained in the mutually correlated functions of the acoustic method for inspection of underground pipelines. The method has been tested in intensive leak inspection of urban heating pipelines and potentially could be beneficial for detecting leaks in the early stages of their occurrence in underground pipelines of the essential service water system at NPPs.
Toronto’s Little India in Residential Context: A Geographical Analysis of Census Data
Authors: Ritchie Isabel , Bauder Harald
Published: September 2022

Ethnic economies are an important part of the today’s global city. We examine Toronto’s Little India and map the corresponding ethnic and Visible Minority population and their residential locations across the Toronto Census Metropolitan Area (CMA). Although past research suggests that ethnic economies are typically accompanied by a local co-ethnic residential population, our study shows that this is not the case for Little India. While the South Asian population around Little India is increasing, it is growing at a slower pace than in some other parts of the Toronto CMA. We identify and examine four major South Asian residential clusters across the Toronto CMA that represent a potential customer base for the businesses of Little India.  
An Investigation Into The Comparability Of Common Jet Engine Materials With Next Generation Biofuels
Authors: Yoon Paul
Published: September 2022

Growing concerns regarding the environmental impact of burning fossil fuels and energy independence has spurned the transportation industry into developing a more eco-friendly and sustainable way to travel. The most promising frontier in this endeavor is the development of alternative fuels that will significantly reduce the carbon footprint of our current engines with little or no modifications required. The effect that one of these frontier fuels may have, camelina based biofuel, on various fuel system materials was evaluated in this report in accordance with ASTM D4054 in the form of a 50:50 mixture. The materials went through an immersion process at varying temperatures and tested under the numerous standards outlined by the American Society for Testing and Materials (ASTM). The results were compared to a benchmark Jet A1 fuel since the effects of this fuel on current fuel system materials is extensively known. The purpose of this research is to determine the viability of using a 50:50 biofuel mixture in current aircraft fuel systems by evaluating the physical properties after being fuel treated. The results showed that the biofuel mixture affected the non-metallic materials in varying degrees, while not affecting the metallic materials.
PENGARUH KEPEMILIKAN INSTITUSIONAL, UKURAN PERUSAHAAN, LEVERAGE DAN TRANSFER PRICING TERHADAP TAX AVOIDANCE (Studi pada Perusahaan Pertambangan yang Terdaftar Dalam Bursa Efek Indonesia Tahun 2014-2018)
Authors: Sadeva Bramantiyo Sonny , Suharno Suharno , Sunarti Sunarti
Published: September 2022

Tax avoidance is an effort made by the company to save tax payment that can be done legally. The purpose of this study to determin (1) the effect of institutional ownership on tax avoidance (2) the effect of size firm on tax avoidance (3) the effect of leverage on tax avoidance (4) the effect of transfer pricing on tax avoidance. This study uses secondary data in the form of audited financial statements originating from the Indonesia Stock Exchange (IDX). The population in this study is the mine industry during the 2014-2018 observation period. In this study used a purposive sampling method to represents a group of non-probability sampling techniques. This study uses multiple linear regression data analysis techniques with the results of the study show that institutional ownership do not have a significant influence on tax avoidance, size firm and transfer pricing have a positive and significant effect on tax avoidance, and leverage have a negative and significant effect on tax avoidance.
PENGARUH SANKSI PERPAJAKAN, PEMERIKSAAN PAJAK, KEPATUHAN WAJIB PAJAK DAN KESADARAN WAJIB PAJAK TERHADAP PENERIMAAN PAJAK PENGHASILAN (Studi Kasus di Kantor Pelayanan Pajak Pratama Sukoharjo)
Authors: Prabowo Didik , Harimurti Fadjar , Sunarti Sunarti
Published: September 2022

The purpose of this research is to analyse the significance of taxation sanctions, tax checks, taxpayer compliance and taxpayer awareness on the acceptance of income tax at Sukoharjo Primary Tax Service office. The population in this study is a taxpayer of a personal person registered with the primary Tax Service office of Sukoharjo until August 2019. Sampling techniques use purposive sampling, with a sample count of 40 respondents. Data collection methods used: questionnaires and documentation. Technical analysis of data used for validity tests, reliability tests, classical assumption tests, and multiple linear regression analyses. The results of the study gained the conclusion that there was a significant positive influence on taxation sanctions on income tax revenues. There is a positive and significant influence on tax checks on income tax revenues. There is a significant positive influence of taxpayer compliance with income tax acceptance. There is a significant positive influence of taxpayer awareness towards income tax acceptance.
PENGARUH RASIO KEUANGAN TERHADAP FINANCIAL DISTRESS PADA PERUSAHAAN TELEKOMUNIKASI
Authors: Sari Sekar Mayang , Utami Setyaningsih Sri , Indriastuti Dorothea Ririn
Published: September 2022

The purpose of this study was to analyze the effect of liquidity ratios, leverage, and profitability on financial distress in telecommunications companies listed on the Indonesia Stock Exchange in 2013-2019. The population in this study were 6 companies listed on the Indonesia Stock Exchange in 2013-2019. Sampling with saturated sampling method and obtained 6 samples. Collecting data using documentation techniques through the Indonesia Stock Exchange website. The analysis technique used is the classical assumption test, multiple linear regression analysis, t test, F test, and the coefficient of determination. The results showed that simultaneously and partially the ratio of liquidity, leverage, and profitability had a simultaneous effect on financial distress.
PENGARUH PENDIDIKAN, SELF EFFICACY, DAN KOMITMEN ORGANISASI TERHADAP KINERJA PENDAMPING SOSIAL
Authors: Norhalisa Linggar , Suprayitno Suprayitno , Sutarno Sutarno
Published: September 2022

Penelitian ini bertujuan untuk mengetahui pengaruh pendidikan, self efficacy, dan komitmen organisasi terhadap kinerja pendamping sosial. Sampel pada penelitian ini adalah pendamping sosial kecamatan Kartasura sebanyak 37 orang. Penelitian ini merupakaan penelitian diskriptif kualitatif dan kuantitatif. Teknik pengambilan sampel menggunakan teknik sampel total. Teknik pengumpulan data dilakukan dengan metode kuesioner.Teknik analisis data menggunakan analisis deskriptif, regresi linier berganda, uji t, uji F, dan koefisien determinasi.Hasil penelitian ini menunjukkan bahwa secara parsial maupun secara simultan pendidikan, self efficacy, komitmen organisasi berpengaruh signifikan terhadap kinerja pendamping sosial kecamatan Kartasura.
FAKTOR-FAKTOR YANG MEMENGARUHI INTEGRITAS LAPORAN KEUANGAN
Authors: Hidayah Laila , Fauziah Fitri
Published: September 2022

Tujuan penelitian untuk mengetahui pengaruh kualitas audit, ukuran perusahaan, kepemilikan institusional dan kepemilikan manajerial terhadap integritas laporan keuangan pada perusahaan manufaktur sektor aneka industri yang terdaftar di BEI tahun 2015-2019. Sampel penelitian ini adalah perusahaan Manufaktur sektor aneka industri yang terdaftar di Bursa Efek Indonesia (BEI) periode 2015-2019. Pemilihan sampel menggunakan metode purposive sampling. Teknik analisis data menggunakan analisis regresi linier berganda. Hasil penelitian disimpulkan bahwa kualitas audit dan ukuran perusahaan berpengaruh negatif terhadap integritas laporan keuangan. Kepemilikan institusional dan kepemilikan manajerial tidak berpengaruh terhadap integritas laporan keuangan
The Impact of Using Model and Augmented Reality Technology on Students’ Science Achievement, Motivation, and Interest Levels
Authors: SİVRİ Şeyma Nur , EROĞLU Eylem
Published: September 2022

In this study, it was aimed to investigate the effects of modelling and the material designed with augmented reality technology on the academic success of students, their motivation, and interest levels towards the science course. The study was conducted in 6th grade science units of "Support and Movement System" and "Systems in Our Body". In the study, quasi-experimental design with pre-test post-test control group was applied. The study was carried out with three groups: the control group, the augmented reality experimental group and the modeling experimental group. The research sample consists of a total of 66 students studying at a public middle school in the Küçükçekmece district of Istanbul province, during the 2020-2021 academic year. To collect data, a 30-item Science Achievement Test, a 23-item Science Motivation Scale, and a 27-item Science Interest Scale were applied. Kruskal Wallis test was applied for multiple comparisons, and Mann Whitney U tests were carried out for post-hoc comparasions. Wilcoxon Signed Ranks tests were applied for intragroup comparisons. According to the results of the study, it was concluded that the use of augmented reality and modeling technique in the science course had a statistically significant effect on the academic success, motivation, and interest of the students towards the science course.
Estado y regulación social de la muerte
Authors: Navarro Cosme Damián
Published: September 2022

El escrito presenta elementos para comprender el papel del Estado en el tratamiento social de tres casos de muertes excepcionales en el nordeste argentino, ocurridos entre 2012 y 2017. Para ello, recupera los conceptos de construcción estatal de las mentalidades y conciencia colectiva, presentes en las teorizaciones de P. Bourdieu (1997), P. Corrigan y D. Sayer (2007) sobre el Estado y su función de construir ideas desde las cuales se interpreta y actúa en el mundo social. Partiendo de allí, reconoce una serie de “rituales” o formas típicas de acción, tendientes a constituir un ordenamiento acorde al desarrollo del sistema económico; entre las cuales destaca la administración de la vida en función de su utilidad y el descarte de los cuerpos sobrantes, como fundamento para la inacción estatal en el tratamiento de los casos referidos.
Experiencia antropológica, muerte y salud intercultural en Catamarca (Argentina)
Authors: Martínez Bárbara
Published: September 2022

Nutriéndose de los aportes conceptuales y metodológicos de la antropología crítica, este trabajo presenta y explora los derroteros de campo etnográfico en la construcción de un Proyecto de salud intercultural en la provincia de Catamarca, Argentina, en la década de 2010, que surgió a partir de la demanda de los sectores involucrados. En particular, analiza los derroteros profesionales que se plantearon desde las disputas iníciales, y que continuaron en la organización, y en los primeros resultados de la experiencia. Asimismo, reflexiona sobre la salud como un proceso de construcción política, las trayectorias de la comunicación entre las partes, y el rol profesional de la antropología en estos contextos.
política de tierras y colonización en Chaco durante el Plan Trienal (1973-1976): planificación y análisis para un campo en transformación
Authors: Almirón Adrián Alejandro
Published: September 2022

La política de colonización durante la década del setenta en el Chaco ocupó un lugar preponderante, en especial durante el segundo gobierno de Deolindo Bittel entre los años 1973-1976. Estas medidas se relacionaban al denominado Plan Trienal planificado por el tercer gobierno de Juan Domingo Perón, las cuales buscaban promover la productividad agrícola y fortalecer la expansión de las áreas extrapampeanas. De esta forma, el artículo plantea analizar la reconstrucción de los proyectos de colonización diseñados por el Estado nacional y provincial. Estudiaremos el rol de las instituciones y de los  expertos en la formulación y en los trabajos realizados en el territorio a fin de lograr  cambios en el agro chaqueño.
electrificación del Sur de Santa Catarína: de las primeras iniciativas para la interconexión de los sistemas eléctricos
Authors: Farías de Moraes Fabio
Published: September 2022

El contenido de este artículo analiza las iniciativas privadas en el sector eléctrico en la región sur de Santa Catarina, desde las primeras décadas del siglo 20. Trata de la formación de las primeras redes con un alcance local, pasando de la interconexión regional, liderada por inversiones estatales, a la interconexión a sistemas más grandes, con cobertura en el sur de Brasil. Inicialmente, se enumeran algunos de los principales sistemas aislados, que, repartidos por el territorio sur de Santa Catarina, sirvieron a las diversas ubicaciones. En primer lugar, el elemento unificador de un sistema regional, la Central Termoeléctrica de la Siderúrgica Nacional ocupa un espacio en nuestra exploración. En segundo, otra inversión estatal de gran relevancia para la electrificación del sur del estado, el Complejo Termoeléctrico Jorge Lacerda, tiene un papel central. Finalmente, con algunas consideraciones panorámicas sobre el resultado de la electrificación en la región, finaliza este artículo.
Estudio de las necesidades de capacitación del entrenador empresarial en hoteles del destino turístico de Varadero.
Authors: Del Toro Soto Maithé del Toro Soto , Jiménez Valero Bisleivys , Velastegui López Luis Efraín
Published: September 2022

La capacitación del entrenador empresarial repercute en el desarrollo de las organizaciones. El propósito del siguiente estudio consiste en identificar las necesidades del entrenador empresarial en hoteles del destino turístico de Varadero.  Como escenario propicio se seleccionó un hotel de cada grupo hotelero (Cubanacán, Gran Caribe e Islazul). Para ello se empleó una encuesta de elaboración propia que contiene datos generales ocho preguntas, donde, las respuestas son de marcaje rápido y sencillo. Los resultados del diagnóstico muestran las dificultades en las acciones de capacitación para contribuir al desempeño exitoso de los entrenadores empresariales. Las debilidades más señaladas se inscriben en lo referido a la, la metodología de la enseñanza, el dominio de técnicas participativas, la actualización de los sistemas de conocimientos, las habilidades con las TIC. Presentan insuficiencias también en lo relativo a la participación en cursos de capacitación, en actividades metodológicas y en la participación en eventos. Dentro de las fortalezas se encuentran la formación inicial para el cumplimiento de sus funciones y los años de experiencia profesional de los trabajadores.
PENINGKATAN PENGUASAAN KOSA KATA BAHASA INGGRIS MELALUI METODE PERMAINAN WORD SEARCH GAME DI SISWA KELAS VIII SMPN 4 KOTA TERNATE
Authors: Garwan Suryani , Jusnita Naniek
Published: September 2022

The aim of this research is to know the improvement of word search game method that can increase student‘s English vocabulary acquisition. This research was used Classroom Action Research (CAR) which was done in three circles, each circle explained preparation, action, observation and reflection step. Data sources are students, peers, researchers, documents. The results word search game with method steps: (1) prepare a word search game, (2) Game rules, (3) Divide the group, (4) Division of word search game, (5) the time restriction, (6) Doing word search game, (7) Correcting the work, (8) giving evalution, (9) reward. In the assessmen to flearning out comes increased 100%.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS MACROMEDIA FLASH PADA MATERI SEL SISWA KELAS XI SMA
Authors: Hamid Kurniadi , Masruhim Muh. Amir , Hudiyono Yusak
Published: September 2022

This research is a development research. The aim of this research is to produce a media study base on Macromedia Flash to increase the result of study for students class XI in cell course. This development research applies 4-D model which includes define stage, design stage, develop stage, and disseminate stage. Base on the result of media test, obtained a media study base on Macromedia Flash is valid according to validators and qualified: (1) the ability of teachers to manage learning was good criteria,(2) the activity of students in learning process was active,(3) classical learning completeness is achieved,(4) the respond of students in learning component was positive. The result of research in effective class base on descriptive analysis obtained result that a media study base on Macromedia Flash has been fulfilled, among others: (1) result study in class XI reach 92, 86 % students achieved completeness, (2) the ability of teachers to manage learning was good, (3) student’s activity during the class achieved good criteria, (4) the respond of students in learning was positive. Based on the results of analysis data can be concluded that media study learning model base on Macromedia Flash on cell course in class XI senior high school was good quality.
PENGARUH PEMBELAJARAN INKUIRI TERBIMBING TERHADAP KETERAMPILAN PROSES SAINS SISWA SMP
Authors: Taib Halil , Haerullah Ade , Roini Chumidach
Published: September 2022

This research aims to find out the effect of Guided Inquiry Learning Model on students' Science Process Skills. This research is Experimental research designed. The study was conducted at junior high school one West Halmahera which is a state school. The research sample consisted of Class VIIA as Experiment Class and Class VIIC as Control Class. There are 32 students in each class. The research instrument used was a questionnaire for the product expert validation test. The Science Process Skill Test with inferential analysis uses the ANACOVA test to test the research hypothesis. The results of the study showed that the science process skills of students in the pre-test had a significant value (p) of 0,000 while for the guided inquiry model of 0.010. The test results in Table 1 also obtained a significance value (sig) of 0,000. This significant value is smaller than the alpha value of 0.05, so the statistical hypothesis (Ho) is rejected and accepts the research hypothesis. Thus, it can be concluded that there is a significant influence of guided inquiry learning models on the science process skills of students of junior high school one West Halmahera.
PENERAPAN MODEL PEMBELAJARAN KOOPERATIF TIPE THINK PAIR SHARE UNTUK MENINGKATKAN HASIL BELAJAR BAHASA INDONESIA PADA KONSEP MEMBACA PEMAHAMAN SISWA KELAS V SD INPRES LABUHA
Authors: Togubu Ina , Somadayo Samsu , Pamuti Pamuti
Published: September 2022

This study aims to determine the increase in learning outcomes of students in class V SD Inpres Labuha on the concept of reading comprehension by applying the cooperative learning model of the Think Pair Share type and to determine the activities of teachers and students when implementing the type of cooperative learning model Think Pair Share in grade V SD students. Labuha's Inpres on the concept of reading comprehension. The type of research used is Classroom Action Research (PTK). The research was conducted on the fifth-grade students of SD Inpres Labuha. The subjects of the research were 14 students of class V SD Inpres Labuha. The observer consists of two teachers, each with one teacher observing the activities of the teacher and another teacher observing the activities of students in the learning process. The techniques used in this research are test and non-test techniques. The test technique was used to determine student learning outcomes by using questions in the form of essays totaling 4 questions in cycle I and 4 questions in cycle II with a maximum score of 16. both classically and individually. The learning process that has been implemented is in accordance with the learning model Think Pair Share, starting from the stage Think (thinking individually), the stage Pair (pairing with a peer), the stage Share (sharing answers with other partners) can be carried out well by researchers and students class V SD Inpres Labuha. After being analyzed using descriptive statistics, it was found that an increase in student learning outcomes in class V SD Inpres Labuha through the cooperative learning model Think Pair Share on the concept of reading comprehension and the number of students who completed classical learning in the first cycle there were 8 students or 57%, in the second cycle, it increased. to 13 students or 92%, the results of observations on student activity increased by an average of 63% in the first cycle and 77% in the second cycle, while the results of teacher activity observations increased from 85% in the first cycle to 92% in the second cycle.
HAKIKAT BAHASA, NASIONALISME, DAN JATIDIRI BANGSA DALAM KEBIJAKAN PENDIDIKAN BAHASA
Authors: Sukarno Sukarno
Published: September 2022

Indonesia as a large archipelagic country causes Indonesia to have the largest number of regional languages in the world. Each region has its own regional language, so for the purposes of communication that unites the nation, a unified language is needed, Indonesian. Meanwhile, for the purposes of international relations, foreign languages, especially English, are vital. Thus, languages in Indonesia are categorized into regional languages, national languages, and foreign languages. As a means of communication, the language used reflects the function and character of the speaker. This paper discusses the nature of language, nationalism, national identity in language education policy.
THE ROLE OF ENGLISH AS GLOBAL LANGUAGE
Authors: Sofyan Nurlaily
Published: September 2022

English is now used as a lingua franca, most of the native and non-native speakers of English are using English as their mode of communication in their business matters or business organizations. English language is spread all over the world into almost all the fields such as science, engineering and technology, medicine, trade and commerce, scientific research, education, tourism, internet, banking, business, advertising, film industry, transportation, pharmacy and to name a few. The international expansion of English has been predicted and promoted regularly by leaders on both sides of the Atlantic over the past 200 years. In October 1934 the Carnegie Foundation sponsored a conference in New York on ‘The use of English as a world language’. ELF is used in a number of fields in which English is used as the mutual language of choice, such as science, politics, business, and education. The materials of higher education in English is to make it available for the learners and the teachers wherever they are located on this earth, most of the students, teachers and research scholars make use of this opportunity to enhance their qualification as well as knowledge. The widespread of English as an international language and with the advent of the internet as a mode of fast communication channel which has no boundaries, both are mutually enforcing novel trends and bringing tremendous changes in this age of globalization. English is the only language that is internationally spoken and accepted. Furthermore, the impact of the English language on the internet has been disclosed above and it also has been proved that there are many websites using English as their medium of communication. Even though there are certain fields that are not mentioned, it seems that English plays a dominant in those areas also.
Marfan Syndrome and Autosomal Dominant Polycystic Kidney Disease: A Case of Rare Co-occurrence or Coincidence?
Authors: Sekar Arjun
Published: September 2022

Background: Marfan syndrome (MFS) and autosomal dominant kidney disease (ADPKD) are two separate genetic disorders. The author describes the case of a young male with ADPKD who incidentally had Marfan-like features. A literature review was carried out to see if these two disorders could be linked.

Case presentation: A young male presented for incidentally found renal cysts. Kidney function was well preserved, but the patient had positive family history of ADPKD. During routine follow-up, a history of aortic valve disease was mentioned. This, along with the patient’s tall, lean stature and long extremities raised the concern for MFS. A detailed physical examination and workup by other specialists confirmed a clinical diagnosis of MFS. They had no known family history of MFS. The patient has been followed at Associates in Kidney Care, Des Moines, Iowa, USA, for the past 2 years.

Discussion: There are several reports of overlap of ADPKD and connective tissue disorders with an overlap of vascular disorders. ADPKD and MFS are caused by totally different mutations. However, the literature review showed that vascular abnormalities and connective tissue diseases may be more common with ADPKD. Studies have shown that there could be a common signalling pathway for connective tissue disorders when both genes are affected simultaneously. Further research is needed to identify these pathways. More frequent screening of vascular abnormalities might be warranted in those with both phenotypes.
The Voice of One to the Voices of Many: The Story of a Black Girl in STEM
Authors: Saleem Shihadah M.
Published: September 2022

In this article, I take the reader along on my journey as a professional Black woman from Queens, New York, who chose a career in science, technology, engineering, and mathematics (STEM) and education. In this paper, I identify many parallels in the experiences of four students engaged in STEM, through the lens of culturally responsive and sustaining education. I then discuss how these four teenage girls' individual experiences and thoughts converged, due to their participation in a STEM-based summer program. In this narrative, readers will discover how curiosity about STEM, along with sufficient education, determination, and support, can impact the lives of girls, their families, and communities. It also shines a light on the polarization experienced by Black girls and women in education. In the paper, I also reflect on and advise how girls and young professionals can utilize tools and influential people to embrace cultural differences, establish multiple measures of success, and focus on individual ability in order to sustain the stamina and rigor needed to pursue a career in STEM and education.
A New Strategy for Identification of Coal Miners With Abnormal Physical Signs Based on EN-mRMR
Authors: Zhou Mengran , Bian Kai , Hu Feng , Lai Wenhao
Published: September 2022

Coal miners’ occupational health is a key part of production safety in the coal mine. Accurate identification of abnormal physical signs is the key to preventing occupational diseases and improving miners’ working environment. There are many problems when evaluating the physical health status of miners manually, such as too many sign parameters, low diagnostic efficiency, missed diagnosis, and misdiagnosis. To solve these problems, the machine learning algorithm is used to identify miners with abnormal signs. We proposed a feature screening strategy of integrating elastic net (EN) and Max-Relevance and Min-Redundancy (mRMR) to establish the model to identify abnormal signs and obtain the key physical signs. First, the raw 21 physical signs were expanded to 25 by feature construction technology. Then, the EN was used to delete redundant physical signs. Finally, the mRMR combined with the support vector classification of intelligent optimization algorithm by Gravitational Search Algorithm (GSA-SVC) is applied to further simplify the rest of 12 relatively important physical signs and obtain the optimal model with data of six physical signs. At this time, the accuracy, precision, recall, specificity, G-mean, and MCC of the test set were 97.50%, 97.78%, 97.78%, 97.14%, 0.98, and 0.95. The experimental results show that the proposed strategy improves the model performance with the smallest features and realizes the accurate identification of abnormal coal miners. The conclusion could provide reference evidence for intelligent classification and assessment of occupational health in the early stage.
Biodiversity conservation and carbon storage of Acacia catechu willd. Dominated northern tropical dry deciduous forest ecosystems in north-western Himalaya: Implications of different forest management regimes
Authors: Kumar Dhirender , Thakur C. L. , Bhardwaj D. R. , Sharma Nidhi , Sharma Prashant , Sankhyan Neeraj
Published: September 2022

Sustainable forest management is the key to biodiversity conservation, flow of resources and climate change mitigation. We assessed the impact of various forest management regimes (FMRs): legal felling series [(reserve forest (RF), demarcated protected forest (DPF), un-demarcated protected forest (UPF), co-operative society forest (CSF) and un-classed forest (UF)] on biodiversity conservations and carbon storage in Acaciacatechu Willd. Dominated northern tropical dry deciduous forest ecosystems in Nurpur Forest Division of north-western Himalaya, India. The study revealed significant variations in floristic composition, biodiversity indices, population structure and C storage potential among different forest management regimes. The RF and DPF were found to be rich in species diversity and richness whereas the Simpson dominance index for trees and shrubs was maximum in UF and UPF, respectively. The diversity of understory herbs were higher in CSF and UF. The maximum density of seedlings, saplings and poles were recorded in RF followed by DPF and UPF, whereas the minimum density was found in CSF. The tree C density (69.15 Mg C ha−1) was maximum in UF closely followed by RF; whereas the minimum was recorded in CSF (33.27 Mg C ha−1). The soil C density was maximum in RF (115.49 Mg C ha−1) and minimum in CSF (90.28 Mg C ha−1). Similarly, the maximum total ecosystem C density was recorded in RF (183.52 Mg C ha−1) followed by DPF (166.61 Mg C ha−1) and minimum in CSF (126.05 Mg C ha−1). Overall, UF management regimes were shown to have a greater capacity for C storage in vegetation, whereas strict FMRs, such as RF and DPF, were found to be more diverse and have a higher soil and ecosystem carbon density. The study established that in the midst of climate and biodiversity emergencies, it is urgent to maintain, protect and strengthen the network of RF and DPF FMRs for biodiversity conservation, climate change adaptation and mitigation.
Prevalence, indications, and outcomes of operative vaginal deliveries among mothers who gave birth in Ethiopia: A systematic review and meta-analysis
Authors: Balis Bikila , Debella Adera , Ketema Indeshaw , Eshetu Bajrond , Zerihun Ebisa , Deressa Wayesa Alemayehu , Habte Sisay , Alemu Adisu , Bekele Habtamu
Published: September 2022

Background

Operative vaginal deliveries represent an alternative to address problems during the second stage of labor. Clinicians have access to two different instruments obstetrics forceps and vacuum which should be conducted with indication. Understanding the pooled prevalence of operative vaginal deliveries, its indications, and outcomes would help in adopting suitable measures to reduce operative vaginal deliveries-related maternal and neonatal complications. Therefore, this systematic review and meta-analysis aimed to determine the prevalence, indications, and outcomes of operative vaginal deliveries among mothers who gave birth in Ethiopia.

Methods

A literature search was done through databases such as PubMed, SCOPUS, Web of Sciences, CAB Abstract, and CINHAL (EBSCO) to search studies that have been conducted in Ethiopia. Relevant sources were consulted to retrieve unpublished studies. Original observational studies that reported the prevalence, indication and outcomes of operative vaginal deliveries conducted in the English language were identified and screened. Studies were independently assessed for inclusion, data extraction, and risk of bias.

Results

Twelve studies were reviewed. The overall pooled prevalence of operative vaginal delivery among mothers who gave birth in Ethiopia was 10% (95% CI: 8 to 13) with I2 = 98.82% and a p-value ≤ 0.001. Fetal distress, prolonged labor, and maternal exhaustion were the most common feto-maternal indications of OVDs whereas; neonatal death, poor Apgar score, admission to neonatal intensive care unit, perianal tear, and postpartum hemorrhage were complications that occur following the operative vaginal deliveries in Ethiopia.

Conclusion

This systematic review and meta-analysis showed one out of 10 mothers undergo operative vaginal deliveries. Almost all feto-maternal complications that arise following operative vaginal deliveries were preventable. Thus, concerned stakeholders should encourage quality OVDs practice by avoiding unnecessary indications and scaling up the skill of health professionals through special training.

Systematic review registration

http://www.crd.york.ac.uk/PROSPERO/, identifier CRD42022311432.
Population pharmacokinetic models of anti-PD-1 mAbs in patients with multiple tumor types: A systematic review
Authors: Shang Jingyuan , Huang Lin , Huang Jing , Ren Xiaolei , Liu Yi , Feng Yufei
Published: September 2022

Aims and background

A number of population pharmacokinetic (PPK) models of anti-programmed cell death-1 (PD-1) monoclonal antibodies (mAbs) in multiple tumor types have been published to characterize the influencing factors of their pharmacokinetics. This review described PPK models of anti-PD-1 mAbs that investigate the magnitude and types of covariate effects in PK parameters, provide a reference for building PPK models of other anti-PD-1 mAbs, and identify areas requiring additional research to facilitate the application of PPK models.

Methods

A systematic search for analyses of PPK models of eleven anti-PD-1 mAbs on the market that were carried out in humans was conducted using PubMed, Embase, and the Cochrane Library. The search covered the period from the inception of the databases to April 2022.

Results

Currently, there are fourteen analyses on PPK models of anti-PD-1 mAbs summarized in this review, including seven models that refer to nivolumab, four referring to pembrolizumab, one referring to cemiplimab, one referring to camrelizumab, and one referred to dostarlimab. Most analyses described the pharmacokinetics of anti-PD-1 mAbs with a two-compartment model with time-varying clearance (CL) and a sigmoidal maximum effect. The estimated CL and volume of distribution in the central (VC) ranged from 0.179 to 0.290 L/day and 2.98 to 4.46 L, respectively. The median (range) of interindividual variability (IIV) for CL and VC was 30.9% (8.7%–50.8%) and 29.0% (4.32%–40.7%), respectively. The commonly identified significant covariates were body weight (BW) on CL and VC, and albumin (ALB), tumor type, sex, and performance status (PS) on CL. Other less assessed significant covariates included lactate dehydrogenase (LDH), immunoglobulin G (IgG), ipilimumab coadministration (IPICO) on CL, and body mass index (BMI), malignant pleural mesothelioma (MESO) on VC.

Conclusion

This review provides detailed information about the characteristics of PPK models of anti-PD-1 mAbs, the effects of covariates on PK parameters, and the current status of the application of the models. ALB, BW, specific tumor type, sex, and PS should be considered for the future development of the PPK model of anti-PD-1 mAbs. Other potential covariates that were assessed less frequently but still have significance (e.g., LDH, IgG, and IPICO) should not be ignored. Thus, further research and thorough investigation are needed to assess new or potential covariates, which will pave the way for personalized anti-PD-1 mAbs therapy.
Molecular profile reveals immune-associated markers of medulloblastoma for different subtypes
Authors: Chen Jinyi , Kang Zhuang , Li Shenglan , Wang Can , Zheng Xiaohong , Cai Zehao , Pan Lexin , Chen Feng , Li Wenbin
Published: September 2022

Medulloblastoma, a common pediatric malignant tumor, has been recognized to have four molecular subgroups [wingless (WNT), sonic hedgehog (SHH), group 3, group 4], which are defined by the characteristic gene transcriptomic and DNA methylomic profiles, and has distinct clinical features within each subgroup. The tumor immune microenvironment is integral in tumor initiation and progression and might be associated with therapeutic responses. However, to date, the immune infiltrative landscape of medulloblastoma has not yet been elucidated. Thus, we proposed MethylCIBERSORT to estimate the degree of immune cell infiltration and weighted correlation network analysis (WGCNA) to find modules of highly correlated genes. Synthesizing the hub genes in the protein–protein interaction (PPI) network and modules of the co-expression network, we identify three candidate biomarkers [GRB2-associated-binding protein 1 (GAB1), Abelson 1 (ABL1), and CXC motif chemokine receptor type 4 (CXCR4)] via the molecular profiles of medulloblastoma. Given this, we investigated the correlation between these three immune hub genes and immune checkpoint blockade response and the potential of drug prediction further. In addition, this study demonstrated a higher presence of endothelial cells and infiltrating immune cells in Group 3 tumor bulk. The above results will be conducive to better comprehending the immune-related pathogenesis and treatment of medulloblastoma.
Complement activation in Hidradenitis suppurativa: Covert low-grade inflammation or innocent bystander?
Authors: van Straalen K. R. , Dudink K. , Aarts P. , van der Zee H. H. , van den Bosch T. P. P. , Giang J. , Prens E. P. , Damman J.
Published: September 2022

Hidradenitis suppurativa (HS) is a chronic auto-inflammatory skin disease with a complex and multifactorial pathogenesis involving both the innate and adaptive immune system. Despite limited evidence forlocalcomplement activation, conflicting results have been published on the role ofsystemiccomplement activation in HS. It was hypothesized that complement was consumed in highly inflamed HS skin, trapping complement from the circulation. Therefore, the aim of this study was to evaluate thislocalcomplement deposition in HS skin lesions using routine and commonly used complement antibodies.Direct immunofluorescence for C1q, C3c, C4d, C5b-9, and properdin was performed on frozen tissue sections of 19 HS patients and 6 controls. C5a receptor 1 (C5aR1) was visualized using immunohistochemistry.

Overall, we found no significant local complement deposition in HS patients versus controls regarding C1q, C3c, C4d, C5b-9, or properdin on either vessels or immune cells. C5aR1 expression was exclusively found on immune cells, predominantly neutrophilic granulocytes, but not significantly different relatively to the total infiltrate in HS lesions compared with controls. In conclusion, despite not being able to confirm local complement depositions of C1q, C3c, C4d, or properdin using highly sensitive and widely accepted techniques, the increased presence of C5aR1 positive immune cells in HS suggests the importance of complement in the pathogenesis of HS and supports emerging therapies targeting this pathway.
Electroencephalogram signals emotion recognition based on convolutional neural network-recurrent neural network framework with channel-temporal attention mechanism for older adults
Authors: Jiang Lei , Siriaraya Panote , Choi Dongeun , Zeng Fangmeng , Kuwahara Noriaki
Published: September 2022

Reminiscence and conversation between older adults and younger volunteers using past photographs are very effective in improving the emotional state of older adults and alleviating depression. However, we need to evaluate the emotional state of the older adult while conversing on the past photographs. While electroencephalogram (EEG) has a significantly stronger association with emotion than other physiological signals, the challenge is to eliminate muscle artifacts in the EEG during speech as well as to reduce the number of dry electrodes to improve user comfort while maintaining high emotion recognition accuracy. Therefore, we proposed the CTA-CNN-Bi-LSTM emotion recognition framework. EEG signals of eight channels (P3, P4, F3, F4, F7, F8, T7, and T8) were first implemented in the MEMD-CCA method on three brain regions separately (Frontal, Temporal, Parietal) to remove the muscle artifacts then were fed into the Channel-Temporal attention module to get the weights of channels and temporal points most relevant to the positive, negative and neutral emotions to recode the EEG data. A Convolutional Neural Networks (CNNs) module then extracted the spatial information in the new EEG data to obtain the spatial feature maps which were then sequentially inputted into a Bi-LSTM module to learn the bi-directional temporal information for emotion recognition. Finally, we designed four group experiments to demonstrate that the proposed CTA-CNN-Bi-LSTM framework outperforms the previous works. And the highest average recognition accuracy of the positive, negative, and neutral emotions achieved 98.75%.
Neurologic sequelae of phosphide poisoning: A case report
Authors: Shafiee Dolat Abadi Sahel , Zamani Nasim , Abbasi Sahar , Shojaei Maziar , Hassanian-Moghaddam Hossein
Published: September 2022

Background

Aluminum phosphide (ALP) is extremely toxic with a high mortality rate, mainly due to its cardiovascular complications. Some neurologic effects have also been reported with this pesticide.

Case presentation

We present a 23-year-old male who presented with confusion after ingestion of a toxic dose of ALP. Computerized tomography scan demonstrated diffuse bilateral hypoattenuation of the cerebellar hemispheres, midbrain, thalamus, and globus pallidus resulting in tonsillar and transtentorial herniation and eventually brain death four days after admission.

Conclusions

This is the first documented case of neurologic sequela following phosphide poisoning that emphasizes the importance of brain imaging studies for patients with loss of consciousness.