bluuebunny/crossref_metadata_2025 huggingface dataset:
Differences from Within
Authors:   , Gordon Ari , Chang Mell Joshua , El Haddad Elias
Published: August 2022

The human-restricted bacterial species Moraxella catarrhalis and Haemophilus influenzae are common members of the healthy nasal microbiome, but they are also leading causes of ear infections in children (otitis media, or OM) and of lung exacerbations in adults with chronic obstructive pulmonary disease. Clinical outcomes of colonization are influenced by host and environmental factors, as well as the extensive genetically encoded differences in virulence among isolates of the same species. We performed comparative functional genomics on diverse M. catarrhalis isolated from children with OM to identify genetic and physiological differences associated with severe disease leading to tympanic membrane rupture. This work found that rupture-associated strains were phylogenetically distinct but shared a common global transcriptional pattern when co-cultured with human airway epithelial cells, distinguishing them from more typical strains. Additional analyses suggest that shared genetic differences in rupture-associated strains enhance invasion and survival in airway epithelial cells through their altered regulation of several metabolic pathways. These differences may enhance survival of M. catarrhalis in the middle ear, leading to more severe outcomes for OM patients. We also performed comparative genomic studies on collections of H. influenzae strains to identify genes whose presence or absence are associated with colonization persistence after OM treatment. Collectively, this thesis work has added to the growing evidence that pathogenicity varies among strains of M. catarrhalis and H. influenzae and has identified genes that may be driving these differences.
Law enforcement practice of territorial bodies of military police in criminal proceedings
Authors: Пасько Н.Э.
Published: August 2022

В статье проводится анализ деятельности территориальных органов военной полиции в рамках уголовного процесса. Отдельное внимание уделено правоприменительной практике. Рассмотрено нормативное регламентирование их служебной деятельности. Обнаружен ряд коллизий, имеющих системный характер. Сделан вывод о необходимости своевременного совершенствования существующей нормативно-правовой базы.

The article analyzes the activities of the territorial bodies of the military police in the framework of criminal proceedings. Special attention is paid to law enforcement practice. The normative regulation of their official activity is considered. A number of collisions of a systemic nature have been detected. The conclusion is made about the need for timely improvement of the existing regulatory framework.
New introduction of electronic document management in the field of labor relations
Authors: Кожихин А.П.
Published: August 2022

Рассматриваются новые правовые положения о внедрении в сферу трудовых отношений электронного документооборота на основании изменений в Трудовом кодексе Российской Федерации, внесённых Федеральным законом от 22 ноября 2021 года № 377-ФЗ. Подчёркивается объективная обусловленность указанных новаций активным развитием цифровой экономики и расширением применения в деятельности хозяйствующих субъектов цифровых технологий. Показываются появляющиеся возможности взаимодействия сторон трудовых отношений - работодателя и работника с дополнительным использованием необходимого документооборота в электронном виде.

New legal provisions on the introduction of electronic document management into the sphere of labor relations are being considered on the basis of amendments to the Labor Code of the Russian Federation introduced by Federal Law No. 377-FZ of November 22, 2021. The objective conditionality of these innovations by the active development of the digital economy and the expansion of the use of digital technologies in the activities of economic entities is emphasized. The emerging opportunities for interaction between the parties to labor relations - the employer and the employee with the additional use of the necessary document flow in electronic form are shown.
The possibility of introducing, as well as the objective application of a progressive scale of taxation on the territory of the Russian Federation
Authors: Арабаджийская Е.И. , Останков Д.А.
Published: August 2022

Статья посвящена рассмотрению сущности прогрессивного налогообложения на доходы физических лиц и его отличительным особенностям, позволяющим отличать данную систему налогообложения от других. Актуальность изучения данного явления связана с появлением нововведений в нашем налоговом законодательстве и необходимостью изучения перспектив применения данных новшеств на практике. В работе изучены примеры реализации прогрессивной шкалы налогообложения в других странах, а также приводится теоретический анализ данного вида налогообложения, подробно описывающий как его положительные, так и отрицательные моменты.

The article is devoted to the consideration of the essence of progressive taxation on personal income and its distinctive features that make it possible to distinguish this taxation system from others. The relevance of studying this phenomenon is connected with the appearance of innovations in our tax legislation and the need to study the prospects of applying these innovations in practice. The paper examines examples of the implementation of the progressive scale of taxation in other countries, and also provides a theoretical analysis of this type of taxation, describing in detail both its positive and negative aspects.
Digitalization of legal education: challenges or opportunities
Authors: Дорохов Н.И.
Published: August 2022

В статье рассматриваются состояние, актуальные проблемы и перспективы развития цифровых технологий в области современного юридического образования; обосновываются положения относительно трансформации профессиональной подготовки юристов в цифровую эпоху. Цель представленного исследования заключается в теоретико-методологическом осмыслении места и роли цифровизации, ее инструментария в системе юридической практики и современного юридического образования, выявление и обоснование возможных рисков и оптимальных путей их разрешения с учетом современных юридических реалий. Данный подход, с одной стороны, свидетельствует об очевидной актуальности и востребованности исследования заявленной темы; с другой стороны, требует весьма четких методологических подходов и методов исследования, в их числе – общефилософские (общемировоззренческие) подходы, общенаучные методы (приемы) и в определенной степени частнонаучные (специальные) методы. Основные результаты исследования указывают на комплексный характер цифровизации юриспруденции, включая систему юридического образования; обосновывают общие выводы и рекомендации по реализации потенциала цифровизации как основного тренда дня сегодняшнего.

The article discusses the state, current problems and prospects for the development of digital technologies in the field of modern legal education; substantiates the provisions regarding the transformation of the professional training of lawyers in the digital age. The purpose of the present study is to theoretically and methodologically understand the place and role of digitalization, its tools in the system of legal practice and modern legal education, to identify and justify possible risks and the best ways to resolve them, taking into account modern legal realities. This approach, on the one hand, indicates the obvious relevance and relevance of the study of the stated topic; on the other hand, it requires very clear methodological approaches and research methods, including general philosophical (worldview) approaches, general scientific methods (techniques) and, to a certain extent, particular scientific (special) methods. The main results of the study indicate the complex nature of the digitalization of jurisprudence, including the system of legal education; substantiate general conclusions and recommendations for realizing the potential of digitalization as the main trend of today.
Assessment of Soil in the Vicinity of an Unengineered Landfill
Authors:   Environment Authority, Oman, Raisi Sumaiya Abdul Hameed Al
Published: August 2022

Soil represents a major sink for metals that are released into the environment from various sources, including landfills. Some of these metals may be persistent due to their fairly mobile nature; whereas others are more mobile and have the potential to leach through soil profile at a higher rate, reaching the groundwater. Thus, a pollution problem arises when heavy metals are mobilized into soil solutions and transported to groundwater. Therefore, soil analysis is essential for identifying the characteristics of soil in a study area, relating it to leachate and leachate percolation, and defining the extent of contamination, if any. Due to the growing concern about the risk of groundwater contamination in landfills areas, especially in the widely used unengineered landfills, soil from three newly constructed boreholes in the vicinity of the Al Amirat unengineered landfill in Muscat was examined to determine the extent of soil contamination. The soil assessment indicated that soil samples in the vicinity of Al Amirat landfill do not pose any toxicity because they are not considered hazardous. However, since most metals are mobile within the soil profile, an effect on groundwater might occur in the long run if no action is taken to prevent it.
Study on the Opportunities Related to Coastal Vulnerability in Indonesia Using Bibliometric Analysis
Authors:   Research Centre for Limnology, National Research and Innovation Agency Indonesia (BRIN), Jl Raya Jakarta-Bogor km 46, Cibinong, Indonesia, Daruati Dini , Handoko Unggul , Yulianti Meti , Ridwansyah Iwan , Rahmadya Aldiano , Verawati Dewi
Published: August 2022

Coastal areas have very important roles and benefits. Unfortunately, most of them in the world are experiencing the effects of climatic changes such as rising sea levels, increasing coastal erosion, and marine intrusion. Meanwhile, there have been many studies on coastal vulnerability from various aspects and perspectives. Therefore, it is necessary to study the trend on coastal vulnerability from past historical records of several decades ago and also from the aspects that have not been studied. This study aims to identify gaps and opportunities related to coastal vulnerability to provide solutions to sustainability themes in the future. Also, there is a need for this study since it is not monotonous and contains a novel element. The method used in this review article is Web of Science (WoS) as the database source, while VOSviewer is used to visualize and analyze the Bibliometric maps. WoS is a website that provides subscription-based access to multiple databases that provide comprehensive citation data for many different academic disciplines, while VOSviewer is a software tool for constructing and visualizing bibliometric networks. The analysis shows that for over 20 years, topics related to coastal vulnerability around the world are divided into four categories, each of which shows the most frequently occurring themes, namely climate change, coastal vulnerability, sea level, and vulnerability. Subsequently, there is a gap in coastal vulnerability, which is a topic on climate change that has been rarely studied in Indonesia since 2015. This bibliometric approach is used to identify key themes in each study or scope of knowledge that has been conducted so far, which is beneficialin determining novel future research.
Impact of the Use of the Physics Crocodile Simulator in the Teaching and Learning of Electricity in High School (Morocco)
Authors:   the Faculty of Sciences Dhar Mahraz, Sidi Mohamed Ben Abdellah University, Fez, Morocco, Hamamous Adil , Benjelloun Nadia
Published: August 2022

The integration of Information and Communication Technologies in education is no longer a "pedagogical luxury" also a search for human learning settings that are compatible with today's students' experiences. Computer animations and simulations are the most used technological tools for educational purposes, especially with the lack of experimental equipment in school laboratories, the use of interactive simulations has emerged as a real competitor to the real experience, and an effective alternative to traditional practices. This work aims to study the impact of the use of the simulator crocodile Physics 605, on the understanding and learning of students in the second year of the scientific baccalaureate option physical sciences at the high school Abdellah Laroui of the city of Fez. A comparative study was conducted between interactive simulations using the Physics crocodile simulator and the real experience, considering the acquisition and application of cognitive skills as a key performance indicator. The experiment took place with the adoption of a pre-test and post-test method with an experiment group (25 students) and a simulation group (25 students), the data were then analyzed using the statistical analysis program SPSS v 21, for the analysis of quantitative data, non-parametric Mann-Whitney U tests of independent samples were used. At the end of the session, we invited the students of the simulation group (25 students) to answer on the directive survey questions (closed questions). In addition, the directive type interview (open questions) was conducted with the teachers (10) of physical sciences of the high school Abdellah Laroui of the city of Fez, moreover the data were processed by the software SPHINX v5. The results of the descriptive statistics show that the Physics crocodile simulator has a remarkable effect on the acquisition and application of new knowledge in the lesson on the RC dipole (series association of an ohmic conductor of resistance R and a capacitor of capacitance C); these effects are comparable to those in the real experiment. In addition, the results obtained showed a considerable improvement in some other indicators such as motivation, engagement, and interaction among students compared to the classical method.
Text Selection and Preferences of EFL Students While Reading on Smartphones
Authors:   the Centre for Research in Language and Linguistics, National University of Malaysia, 43600 Bangi, Malaysia, Oh Chen May , Krish Pramela , Hamat Afendi
Published: August 2022

Reading on smartphones is now a common activity due to the variety of platforms that cater to all kinds of users. The number of texts and range of difficulty levels in the English language are significant for EFL students because they affect their language acquisition efforts. This qualitative case study investigates the types of texts that EFL students engage with on smartphones and the approaches they use to select specific texts to read. Students submitted screen recordings of their smartphone activities and justified their actions through interviews. Findings were thematically reported. The study revealed the kinds of texts students engaged with and how they were selected and evaluated. Students generally avoided texts perceived as challenging but attempted texts with topics that attracted them. These findings shed more light on text features that students seek and create awareness for content creators to produce digital content that is engaging and relevant for educational purposes.
Industry and Education Practitioners’ Perceptions Regarding the Implementation of Work-Based Learning through Industrial Internship (WBL-II)
Authors:   the Department of Automotive Engineering, Yogyakarta State University, Yogyakarta, Indonesia, Sutiman Sutiman , Sofyan Herminarto , Arifin Zainal , Nurtanto Muhammad , Mutohhari Farid
Published: August 2022

The crucial problem in implementing Vocational Education on diplomas in Indonesia is the relevance of competence to industry needs, work culture, and sustainable career development. The industrial internship is one of the programs and subjects organized by Vocational Education to unravel the available chain of problems. However, the fact is that the implementation of industrial internships has not positively impacted students. This study explores industry and education practitioners' perceptions regarding applying work-based learning through an industrial internship for Vocational Education Diploma (VED). Fourteen expert practitioners were involved in data collection through semi-structured interviews. Qualitative data were analyzed thematically using NVivo 12. The findings in this study were grouped into two clusters or themes, namely the role of diploma education and the skills needed by students during internships in the automotive industry. The education sector must understand the mindset, internship orientation, program planning, career path orientation in industry, and mastery of case study competencies. Internship students must master the skills of observing, increasing efficiency, productivity, service functions and access to technology, and optimizing interactions with supervisors. The success of WBL-II is in the mutual interest of stakeholders and is integrated with the higher education curriculum. This study is an input for the professional implementation of WBL-II in the future.
Correlation between single pre delivery symphysis-fundal height beyond 36 weeks of gestation and birth weight of newborn after delivery
Authors: Sultana Rahima , Rouf Salma , Shorna Sharmin Akhter , Akter Laila
Published: August 2022

Background: Accurate assessment of fetal weight is important for optimal obstetric management of labouring mothers. Among the methods of fetal weight estimation, symphysis-fundal height (SFH) measurement is inexpensive and non-invasive readily available simple and acceptable procedure of fetal weight estimation. On the other hand, high rate of low birth weight is one of the causes of high perinatal mortality in our country. Objective was to assess fetal birth weight by measuring symphysis-fundal height.Methods: This cross-sectional observational study was conducted in the department of obstetrics and gynaecology, Dhaka Medical College Hospital, Dhaka from July 2017 to June 2018. Total 200 consecutive pregnant women of gestational age more than 36 weeks were selected as per inclusion and exclusion criteria. The fetal birth weight was measured before delivery of the foetus by measuring SFH and using the formula and was compared with actual birth weight.Results: Maximum (35.5%) pregnant mother were in age group 21-25 years followed by 29.5% in 26-30 years, 25.5% in 31-35 years and 9.5% in >35 years age group and mean age was 28.27±4.95 years. Mean weight of new born was 2.81±0.61 kg. Mean symphysis-fundal height 32.76±3.73 cm and maximum (48.5%) pregnant mother had SFH in 35-36 cm group, followed by 30.5% had ≤30 cm and 21.0% had 31-34 cm in this study. New born birth weight had significant positive correlation with symphysis-fundal height.Conclusions: Symphysis-fundal height has significant positive correlation with birth weight of new born.
The protein C deficiency and its effects on in-vitro fertilization outcome and recurrent pregnancy loss: a Syrian cohort study
Authors: Khoury Fadi , Deeb Haya , Jarouj Rana , Khoury Hanna , Alhalabi Nawras , Alhalabi Marwan
Published: August 2022

Background: Protein C deficiency is a rare disease; it could be primary or secondary. Female patients with protein C deficiency may develop pregnancy-associated thrombosis. The clear association between the protein C deficiency and fertility or in-vitro fertilization (IVF) results has not been known yet. In our study, we aimed to determine the prevalence of protein C deficiency in Syrian infertile women and to assess the impact of protein C deficiency on abortion, recurrent IVF Failure, and IVF results.Methods: the electronic patients’ results were retrospectively screened. A total of 238 women, who had IVF cycles between January 2012 and December 2017 in a tertiary care hospital, met our including criteria.Results: the prevalence of protein C deficiency was 13.45%. There was a significant association between the protein C level and recurrent pregnancy loss (RPL). Furthermore, the protein C deficiency has an impact on the IVF results. Additionally, we did not find any association between protein C deficiency and age or number of previous IVF cycles.Conclusions: the protein C could be the hidden factor that affects IVF results. More research should be done to better understanding the role of protein C in infertility and IVF.
Efficacy of the Swede score in prediction of high-grade lesions of cervix
Authors: Chowdhury Lipika , Chowdhury Shahanara , Banu Nasreen , Sharmin Zenifar , Tabassum Masuma , Sultana Marjan , Alam S. K. Tasnuva
Published: August 2022

Background: Cervical cancer is a preventable lesion that can be identified by stepwise screening methods. Visual inspection of the cervix with acetic acid, Lugol’s iodine, pap smear, and HPV are the primary screening methods. This study aims to evaluate the efficacy of the Swede score in predicting high-grade lesions of the cervix among patients attending a colposcopy clinic. Methods: This observational cross-sectional study was performed in a colposcopy clinic under the department of obstetrics and gynaecology at CMCH. All referral patients to the colposcopy clinic were the study population. Women aged between 25-65 years was the study subject. Results: Majority (47.5%) of the patient’s Swede score was 4 and 20.1of % of patients had scores of 5-6 and only 1.3% of patients had scores ≥7%. 63 (79%) patients had low grade/normal/ cervical intraepithelial lesion (CIN) 1, 16 (20%) patients had high grade/non-invasive cancer/CIN 2 and only 1 patient had high grade/suspected invasive cancer/CIN 3. A score of 6 had a specificity of 100% for CIN 2 with a sensitivity of 30% positive and negative predictive value (PPV=100%; NPV=90.9%). Lowering the score to 5 for predicting CIN 2 improved the sensitivity at the expense of specificity (sensitivity=60%; specificity=90%; PPV= 94%; NPV=46.2%).Conclusions: Swede scoring system is consistent and reproducible, has a simple structure, and thus contributes to preventing cervical cancer. Swede score of 6 or more has 100% specificity; this scoring method is a preferred method for the treatment of high-grade CIN.
Fetal growth and its correlation with level of glycemic control in pregnancy with diabetes: an observational study in tertiary care centre of North India
Authors: Sharma Akanksha , Pandey Amita , Das Vinita , Agrawal Smriti
Published: August 2022

Background: Diabetes in pregnancy is a known risk factor for macrosomia and intensive glycemic control is a well-known strategy to prevent this macrosomia. However, does this tight glycemic control is actually beneficial or is it one of the reasons for small for gestational age babies in these women? Is a clinical enigma. We planned this study to see effects of glycemic control on fetal weight and to answer if tight control is always better.Methods: This prospective observational study was conducted in the department of obstetrics and gynaecology in a tertiary care centre (King George medical university) over a period of one year (June 2017-June 2018). All pregnant women with GDM and pre-gestational diabetes with singleton pregnancy were registered in the study after proper consent, followed up for glycemic control, fetal weight. Antepartum risk factors and complications of diabetes were also noted in these women.Results: Total 88 patients included in the study. Five with pre-gestational diabetes, 83 with GDM. Small for gestational age neonates were seen in 54.1% cases, large for gestational age were seen in 2 cases and rest of neonates were appropriate for gestational age. 89.4% had good glycemic control, 7% had over-zealous glycemic control and 3.5% had under-controlled sugars.Conclusions: The results in the study strongly supported the efficacy of good glycemic control in prevention of LGA/macrosomia. However, optimal glycemic control in third trimester does not guarantee appropriate weight of fetus as incidence of SGA/FGR neonates was fairly high (53.9%) even in good glycemic control group.
Histopathological evaluation of endometrial patterns in workup of abnormal uterine bleeding
Authors: Raman Jayasree , Pushpangadan Prakash , Philip Febby K. , Pillai Shobha S.
Published: August 2022

Background: Abnormal uterine bleeding (AUB) is defined as bleeding pattern that differs in frequency, duration and amount from the normal cyclical flow. Endometrium in AUB vary depending on etiology and age. The present study attempts to categorize the histopathology of endometrium in abnormal uterine bleeding in women of various age groups.Methods: A hospital based prospective study was carried out in 220 cases of abnormal uterine bleeding. Paraffin processed endometrial biopsies analyzed correlating the clinico-radiological data. Endometrial samples of infertility and pregnancy related bleeding were excluded.Results: 220 cases of AUB from 25 years to 78 years of age were evaluated under three groups, reproductive (23%), perimenopausal (52%) and postmenopausal (25%). AUB was most common in the perimenopausal group. The predominant pattern seen was physiological cyclical endometrium (67.2%). Disordered proliferative endometrium (18.63%) was the predominant abnormal pattern. Malignant lesions were (99.5%) in postmenopausal age and disordered proliferative endometrium seen predominantly (65.85%) in perimenopausal age group. As per PALM-COEIN classification, uterine structural abnormalities (PALM) were found in 70 (31.9%), non-structural causes (COEIN) in 150 (68.1%). Endometrial thickness >16 mm on radiology were seen in endometrial carcinoma.Conclusions: Endometrial morphology vary with ovulatory abnormalities, anovulation and uterine abnormalities. Acronym PALM-COEIN is useful in categorizing AUB. The incidence of disordered proliferation, hyperplasia and malignancy seen in extremes of age, reiterates that early clinic-radiological workup and endometrial study are the mainstay in early detection of lesions.
Art and craft of episiotomy
Authors: Patil Gayatri L. , Pujar Tejaswi V. , A. S. Sridevi , Priya Edamadaka Vishnu , B. K. Sridevi
Published: August 2022

Background: Episiotomy is the most common obstetric surgical procedure performed in labor room. Mediolateral and Midline episiotomies are the most common types. Post-delivery suture angle is the most important determinant factor which predicts the risk of anal sphincter injuries. Mediolateral episiotomy has a significantly lower risk of OASIS rate when compared to midline episiotomies. Aim of the study was to know whether mediolateral episiotomies are actually mediolateral and does the angle of episiotomy influences the risk of anal sphincter injuries, maternal/fetal complications in the perinatal period.Methods: An observational study was conducted on 250 postpartum patients admitted to our hospital. Details of episiotomy in relation to incision angle, length, depth and post suturing angle were noted within two days of delivery.Results: Among the subjects included there were 40.8 % incisions were RMLE, average length was 3.32cms, average suture angle is 28.69 degree. OASIS was seen in 19.5% cases more so with midline episiotomies.Conclusions: Episiotomy is an essential, must to know skill. Compulsory ssupervised clinical teaching and use of skill lab training can prevent potential detrimental consequences.
A comparative study of spontaneous versus induced labor in primi and multiparous women at tertiary care centre
Authors: Damor Priyanka , Chavhan Suresh Kumar
Published: August 2022

Background: Objectives of the study were to compare progression of spontaneous versus induced labor in primigravida and multigravida women.Methods: Pregnant women admitted in labor room of RNT medical college Udaipur during January 2021 to June 2021 were selected for this study. A total of 200 pregnant women were selected and divided into two groups. Women in group A were induced while in group B were women with spontaneous onset of labour. Labor progression in both was compared.Results: In group A, the mean duration of active phase in primigravida was 4.08+2.30 hr. In group A, the mean duration of the second stage in a primigravida was 25.5+8.15 min and in a multigravida was 17.38+9.95 min. In group B,the mean duration of second stage in a primigravida was 41.3+9.6 min, while in a multigravida was 22.72+6.2h. The mean duration of active phase in group A in the primigravida and multigravida was almost similar, showing that induction does not have any effect on the duration of active phase. The mean duration of the second stage of group A in primigravida was 25 min and multigravida were 17 min showing that induction reduces the duration of the second stage.Conclusions: Induction of labor when done at the right gestational age for correct indication is beneficial to women as it reduces the complications caused due to the continuation of high-risk pregnancies.
Transfer or not to transfer? a medical dilemma
Authors: Singh Neeta , Patel Garima , Saini Monika , Sethi Ankita
Published: August 2022

Morphological assessment predominantly determines the quality of embryos although, several methods are available for it. Dilemma to transfer arises when clinicians are left with mere poor grade embryos. This case report encompasses a case of 37 years primary infertile female managed with GnRH antagonist cycle for tubal factor infertility. Post ovarian stimulation and ovum pickup, only two 4 celled grade-C embryos were available for transfer. Reluctantly the embryo was transferred, but fortunately resulted in a healthy live intrauterine pregnancy. This case report questions the aptness of the current methods to determine embryo quality and also enlightens whether the ethical or medical conundrum holds true regarding relation between embryo quality and chances of a fruitful pregnancy.
A case report of incidentally elevated maternal serum alkaline phosphatase managed in a poor resource setting
Authors: Naik Salonee Milind , Naik Pornima Rajkumar
Published: August 2022

The normal serum concentration of alkaline phosphatase (ALP) in adults ranges from 47 to 147 IU/l. Alkaline phosphatase is known to be produced by syncytiotrophoblasts in the placenta during pregnancy. Its levels are normally increased in pregnant women and levels of up to twice the upper limit can be considered normal.  There have been case reports pointing out that an abnormal rise in serum ALP levels could be a marker for placental insufficiency preterm delivery. Here we report a case with delivery of a normal infant and no placental pathology at term. There are very few reports of extreme elevations of ALP in a pregnancy without any co-morbidities and delivery of normal infant with a subsequent decline to normal after delivery. We present the case of a 23-year-old pregnant woman with an incidentally detected 10 fold elevated serum ALP which was managed at a sub district level hospital which is a poor resource setting. She was expectantly managed and delivered a healthy new-born with an unremarkable intrapartum and post-partum period. Her ALP levels were monitored during the peri-partum period and gradually declined. This case is important because it shows that an isolated increase in a biochemical marker can give a good feto-maternal outcome after expectant and vigilant management.
Factors related to the death of diabetic patients with COVID-19 hospitalized in Joseph Raseta Befelatanana University Hospital in Antananarivo, Madagascar
Authors: Andrianiaina Miora M. A. , Randrianomanana Tsikinirina V. , Raherison Rija E. , Razanamparany Thierry , Raharinavalona Sitraka A. , Rafamatanantsoa Jean F. , Rakotomalala Andrianirina D. P. , Andrianasolo Radonirina L.
Published: August 2022

Background: Diabetes mellitus is associated with severe and even fatal forms of COVID-19. The objective of this study was to identify the factors linked to the death of COVID-19 diabetic patients in order to improve their care.Methods: An analytical cross-sectional study was carried out in the endocrinology department of the Joseph Raseta Befelatanana University Hospital Center, Antananarivo, Madagascar. It has concerned all the cases of COVID-19 diabetics (162 patients) recorded from April 2020 to July 2021 (16 months).Results: In our study, the case fatality rate of COVID-19 in diabetics was 14.49%. Significant factors related to death, after univariate analysis, were:  vascular complications including nephropathy (OR=4.74), neuropathy  (OR=5.38) and ischemic heart disease (OR=3.9), presence of other comorbidities (OR=9.02), dyspnea (OR=4.60), seizures (OR=6.22) or alertness disorder (OR=4.35), lower oxygen saturation (p=0.04), pleurisy (OR=4.67), signs of cardiac decompensation (OR=3.46), an elevated mean blood sugar level (p<0.001), leukocytosis (p=0.02) and thrombocytopenia (p<0.001), impaired renal function (p=0.02) and pleurisy on chest imaging (OR=5.29).Conclusions: Death factors in diabetics with COVID-19 can be diverse. They do not only include the cardiovascular complications of the diabetes, but also a worse clinical respiratory presentation on the admission, a higher inflammatory syndrome, and a greater imbalance of blood sugar during the hospitalization.
Analgesic effects of caudal dexmedetomidine versus midazolam combined with bupivacaine on postoperative pain following paediatric infraumbilical surgeries
Authors: Oruobu-Nwogu Ayanate , Aggo Alfred T. , Johnson Uyoata U.
Published: August 2022

Background: There is continued search for an ideal adjuvant necessitated by the limited duration of singleshot caudal block. The study aimed to compare the analgesic effects of caudal 1.5 µg/kg dexmedetomidine versus 50 µg/kg midazolam combined with 0.20% bupivacaine in children.Methods: Following ethical approval and parental consent, 66 American Society of Anesthesiologists (ASA) class I or II children aged 1-6 years were randomized into three groups (A, B, and C) of 22 each. All patients had laryngeal mask airway (LMA) general anaesthesia induced with propofol and maintained with isoflurane in 100% oxygen. Group A received 1 ml/kg 0.20% bupivacaine and 1.5 µg/kg dexmedetomidine (1 ml), B received 1 ml/kg 0.20% bupivacaine plus 50 µg/kg midazolam (1 ml) while C received 1 ml/kg 0.20% bupivacaine and 0.9% normal saline (1 ml), via the caudal space. Pain was assessed using the face, leg, arm, cry, consolability (FLACC) scale. The time to first analgesic request, (TTFAR) was defined as the period from caudal injection to pain score of ≥4. Analgesic was given when FLACC score was ≥4.Results: All 66 children completed the study. The TTFAR was longest in group A (14.4±2.36), followed by group B (12.0±3.69), and shortest in group C (5.6±1.45), p=0.01, with greatest 24 hours analgesic consumption in group C, p=0.01.Conclusions: Caudal dexmedetomidine or midazolam combined with bupivacaine significantly prolonged the analgesic duration, with superiority of dexmedetomidine over midazolam group in analgesic profile.
Training course on emotional intelligence effect of nurses’ interpersonal relationship style on Tabanan General Hospital
Authors: Prihandhani I. G. A. A. Sherlyna , Hakim Nina Rismawati
Published: August 2022

Background: A skill training course on emotional intelligence is primary when it comes to nursing practice, contradicting the result of a particular research, exposing the fact that ample numbers of nurses are lacking the adequacy of interpersonal relationship which remains ignored instead. In consequence, a strategy in increasing nurses’ interpersonal relationship style through a training program is viewed as necessary. The aim of the study was to recognize training course on emotional intelligence (TCEI) effect of nurses’ interpersonal relationship style on Tabanan General Hospital.Methods: This research was designed as quasi-experiment including both pre-test and post-test with the use of control group. The corresponding population was all 78 nurses at the agency of Tabanan General Hospital determined by a technique of total sampling. The method to teach emotional intelligence includes both techniques of exploration and reflection, for instance brain storming, question and answer session, case analysis, small group discussion, and critical thinking on emotionality. The instrument used was interpersonal style inventory rating scale questionnaire with its validity and reliability been tested.Results: The result of this research exposes the presence of TCEI effect nurses’ interpersonal relationship style on Tabanan General Hospital with the value of p≤0.0001. In addition, it as well shows an increasing score in regard with the TCEI. Concluding from the statistic test using Wilcoxon, it is stated the said increasing score is worth p≤0.0001.Conclusions: The TCEI has been proven to have an influence on nurses’ interpersonal relationship style on Tabanan General Hospital.
Sexual dimorphism of nasal index, nasal breadth and nasal height among young Kashmiri population
Authors: Gulzar Shameema , Hussain Ashaq , Kumar Irshad Ahmad , Itoo Mohd Saleem , Mir Nasir Sayeed
Published: August 2022

Background: Nose contributes as a very important and prominent part of the face; and occupies the most visible position on normafrontalis. There is an anthropometric harmony between different structures of face including nose, lips, eyes, forehead, chin and cheek. Our study was aimed to determine sexual and ethnic differences in external nose measurements of young adult Kashmiri population and to provide baseline data for reconstructive cosmetic surgeons and forensic experts.Methods: This study was conducted among 300 healthy participants (150 males and 150 females) belonging to Kashmiri population. Nasal height, length and breadth were measured using a vernier caliper. Then, the nasal index was determined for each subject. The obtained data was subjected to statistical analysis.Results: In case of males, mean nasal index was 83.31±12.31 mm, mean nasal length was 57.28±4.51 mm, mean nasal breadth was 48.41 mm and mean nasal height was 36.17±20.9 mm, while in case of females mean nasal index was 226.83±46.41 mm, mean nasal length was 50.16±3.54 mm, mean nasal height was 13.97±2.01 mm and mean nasal breadth was 31.02 mm.Conclusions: Nasal type among the Kashmiri male population is predominantly mesorrhine while in females it is hyperplatyrrine or very wide nose.
A study to assess the level of knowledge regarding prevention and management of acute respiratory infection among mothers of children 0-5 years in selected hospital in Siliguri
Authors: Kumar Primi , Patra Paramita , Paul Rima , Roy Moumita , Khatun Samina , Ghosh Lisa , Dutta Sohini , Roy Rajashree , Sadhu Debalina , Setara Afrin , Naiya Sayanti , Routh Sudipa , Thoki Sneha , Bomzan Sakshi , Barman Mousumi
Published: August 2022

Background: In developing countries like India acute respiratory infection (ARI) contributes in child mortality upto 75% and out of 10, 7 deaths are due to ARI. The knowledge of the mothers towards the disease is a significant determinant of child’s health.Methods: A descriptive cross-sectional study included 100 mothers of children 0-5 years admitted in pediatric ward and postnatal ward in selected hospital Siliguri during the year 2022 in the month of March. Data was collected using structured interview method.Results: 20% of mothers have good knowledge in prevention and 33% had good knowledge in management of ARI.Conclusions: As the leading cause of death among children, knowledge assessment about ARI among the mothers is very important, which helps for better understanding of the intensity of the problem.
Unusual presentation of a rare congenital anomaly: interrupted aortic arch presenting in adulthood with myocardial infarction
Authors: Rana Abhilasha , Krishnan Venkatram , Jamwal Rupie
Published: August 2022

Interrupted aortic arch (IAA) is a very rare congenital cardiac anomaly in which there is complete interruption of a part of the aortic arch due to abnormal regression of a segment of the left fourth arch during development. The condition usually presents in the neonatal period with abrupt onset cardiac failure and shock after closure of the ductus arteriosus that maintains perfusion distal to the IAA in fetal life. In most cases, immediate surgery is necessary to save the life of the patient. In very rare cases, a massive collateral circulation can develop to compensate for the arch interruption and the condition may remain asymptomatic until adulthood, when it can present with early cardiovascular disease due to the chronic hemodynamic changes. Cross sectional imaging plays a major role in diagnosis and surgical planning in such adult patients. Surgery is usually recommended, even in asymptomatic cases, to prevent early onset cardiovascular diseases. Possibility of previously undiagnosed cardiovascular disease should always be a consideration when evaluating a young patient with myocardial infarction.
An audiological profile of keratitis-ichthyosis-deafness syndrome
Authors: Lonhare Rahul Kumar , Ansari Imran , Sahu Preeti , Mahallik Debadatta
Published: August 2022

Keratitis-ichthyosis-deafness (KID) syndrome is a rare genetic multi-system disorder. It is characterized by defects of the surface of the corneas (keratitis), red, rough thickened plaques of skin (erythrokeratoderma) with sensorineural hearing impairment. The skin of the palms of the hand, soles of the feet and the nails may be affected. Most cases are sporadic caused by mutations in the (GJB2 gene). Most cases are sporadic but familial cases with autosomal dominant inheritance have been reported a rare congenital ectodermal disorder characterized by vascularising keratitis hyperkeratotic skin lesions and hearing loss. The 2-year male child was presented at audiology and speech pathology unit department of ENT at Pt. Jawaharlal Nehru memorial hospital, Raipur, patient came with the complaint of inability to hear since birth. The present report outlined persistent severe sensorineural hearing loss in child with KID syndrome.
An impact of digital accounting on small and medium enterprises in India
Authors: Tailor R. K. , Rajput Ankita , Prasad Gautam
Published: August 2022

A small and medium business person requires cell phone bookkeeping applications that can be utilized to generate monetary details to cross-check the monetary circumstances of their work. Surviving cell phone bookkeeping apps are now universally utilized by SMEs. In this research, the efficacy of cell phone bookkeeping apps was studied. Productive cell phone apps should be uncomplicated for SMEs to operate for generating monetary details in line with bookkeeping qualities, and the monetary declarations created must be serene for work holders to utilize.
A preceptoria em enfermagem na pandemia do COVID-19: relato de experiência em uma Unidade Básica de Saúde em Cacoal/RO
Authors: Reco Cruz Jessíca , Cesar Schweickardt Júlio , Rocha Ernandes Bianca Gabriela , Lopes de Sousa Cássia , Dantas Sara , Teodora Viana Teresinha Cicera , Lelis de Oliveira Wuelison , Chaddad Yamin Filho Marco Antonio
Published: August 2022

No Brasil, a Atenção Primária à Saúde (APS) é uma das portas de entrada para pessoas com suspeita ou confirmação da COVID-19, sendo responsável pela coordenação do cuidado e monitoramento dos casos que apresentem sintomas leves. APS é também compo de ensino prático em enfermagem. Buscamos através do relato de experiência de um estágio supervisionado em enfermagem, numa cidade da Amazônia, estado de Rondônia, fazer alguns apontamentos dos tempos que vivemos. A vivência proporcionou a todos, acadêmicos e à preceptoria, uma visão diferenciada da Atenção Básica e da própria profissão.  Desse modo, podemos dizer que a realização de um estágio e a preceptoria permitiu a reflexão sobre alguns aspectos que envolvem a pandemia: processos de trabalho, orientações sanitárias, educação permanente em saúde e os processos formativos.
Simulação computacional do covid19 por meio do modelo SEIR: efeito do isolamento social
Authors: Kock Kelser de Souza , Duarte Gustavo Chiaradia Ribeiro
Published: August 2022

Objetivos: Simular a evolução da epidemia do COVID19 em uma população hipotética utilizando o modelo SEIR. Métodos: realizou-se uma simulação computacional por meio do modelo SEIR considerando 4 cenários: o isolamento social (Ro=1,5), sem medidas de isolamento (Ro=2,5), aglomeração social (Ro=3,5) e isolamento social durante 90 dias (Ro=1,5) e após sem medidas de isolamento (Ro=2,5). As simulações foram realizadas em um período de 240 dias. Resultados: cenário 1 apresenta 4,57% de infectados; cenário 2 obteve-se 15,4% de infectados; cenário 3 representa 22,9% de infectados; cenário 4, nos primeiros 90 dias obteve-se 4,11% de infectados e após 90 dias, aumentou para 10,71% de infectados. Conclusão: o isolamento social é uma ferramenta imprescindível para o combate a pandemia, não só por diminuir o pico de infectados, como também para achatar a curva de infecções ao longo do tempo.
O (IN)VISÍVEL NO (IN)VISÍVEL: UM OLHAR PSICANALÍTICO SOBRE A RELAÇÃO ENTRE A PANDEMIA DE COVID-19 E A VULNERABILIDADE SOCIAL
Authors: Moreira Francisco Jadson Franco
Published: August 2022

A OMS declarou a COVID-19 em março de 2020, uma pandemia, quando todos os continentes confirmaram casos. Já foi detectado cerca de 330.000 casos em todo mundo, com mais de 14.000 óbitos, demonstrando sua transmissibilidade (número básico de reprodução - R0, estimado entre 1,4 a 5,5) e letalidade estimada em cerca de 4,1% (OMS, 2020).Objetivo: o estudo objetivou apresentar uma reflexão sobre Vulnerabilidade Social e Psicanálise no contexto da Pandemia na cidade de Fortaleza- Ceará- Brasil. Método: Trata-se de um estudo descritivo do tipo reflexivo, realizado em agosto de 2020, por meio de levantamento bibliográfico sobre a temática. Resultados: Apresentam reflexões sobre o laço social direcionado a aspecto da constituição humana e da sociedade em situação de vulnerabilidade social na luta contra o vírus invisível, o estudo elabora também correlações teóricas com conceitos da psicanálise. Considerações Finais pontua espaços de compreensão do ser humano, e oportunidades fundantes para refletir práxis, sobretudo do profissional de psicologia nos atuais dias. O (IN)VISÍVEL NO (IN)VISÍVEL: UM OLHAR PSICANALÍTICO SOBRE A RELAÇÃO ENTRE A PANDEMIA DE COVID-19 E A VULNERABILIDADE SOCIAL
Atenção Primária à Saúde e o contexto da pandemia de COVID-19: reflexões sobre o cuidado em saúde de pessoas idosas
Authors: Buno Carolina Da Silva , Bulgarelli Alexandre Favero
Published: August 2022

O contexto global de emergência em saúde pública causada pela pandemia de COVID-19 desafia os diversos países a pensar estratégias para prevenção e controle da infecção por Sars-CoV-2.  Os idosos são o principal grupo de risco para os casos mais agravados da doença, levando os sistemas de saúde a (re) pensarem seus modelos de atenção e propor estratégias capazes de responder as demandas pré-existentes destes usuários, somados às novas questões evidenciadas pela pandemia. Neste contexto, a Atenção Primária à Saúde (APS) é espaço estratégico para a oferta de cuidados de forma equânime e integral, sendo o principal ponto da rede de atenção acessado pelos usuários idosos. Com o advento da emergência em saúde pública pela COVID-19 este nível de atenção continuou sendo a referência para o atendimento de primeiro contato aos casos sintomáticos respiratórios leves e moderados. Frente tais contextos realizou-se um estudo com aproximação metodológica qualitativa, desenhada dentro de um método indutivo objetivando descrever o acesso aos serviços de saúde na atenção primária na perspectiva dos usuários idosos e traçar um paralelo com questões envolvendo a COVID-19. A produção de informações se deu por meio de entrevistas narrativas semiestruturadas, o material tratado e analisado à luz da técnica de Análise Temática de Conteúdo. Observa-se que houve o aumento das evasões de consultas de acompanhamento e complicações às condições de saúde pré-existentes dos usuários idosos, desafiando a APS a fortalecer as formas de cuidado centradas nos territórios, pautadas, também, na prevenção e promoção ao COVID-19. Novas estratégias para continuidade dos cuidados foram desenvolvidas e ganharam lugar no cotidiano do trabalho das equipes de APS, como as teleconsultas e telemonitoramentos.  Sem estratégias que possibilitem outras formas de cuidado a pandemia de COVID-19 pode representar um fator dificultador de acesso dos usuários idosos aos serviços da atenção primária