bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of interleukin 1β and interleukin 1 receptor antagonist polymorphism genes, Helicobacter pylori infection and the state of the gastric mucosa in the development and progression of gastroesophageal reflux disease
Authors: Zhilina A. A. , Lareva N. V. , Luzina E. V.
Published: November 2020

The mechanisms of the gastroesophageal reflux disease (GERD) development and its complications are analyzed on the tissue and cell levels. That’s why studying polymorphism of interleukin (IL) genes is important. Genotypes IL1β-511Т/Т, IL1β31С/С and IL1RN2/2 (receptor antagonist IL1) associate with high risk of complicated course of GERD disease. Researching genes polymorphism of the pro-inflammatory cytokines of the patients having gastroesophageal reflux disease and changes in gastric mucosa it was determined that genotype IL1β-511Т/Т is associated with the deeper local level of IL1β. Meanwhile the patients having erosive esophagitis had lover level of IL1β. It was determined that genotype IL1RN2/2 and haplotype IL1RN*2 /IL1В-31*Т are connected with the high risk of esophagus cancer of patients having Helicobacter pylori. Genotype IL1β-511Т/Т and haplotype IL1β-511Т/Т /IL1RN1/1 of the patients having GERD are associated with the low risk of the esophagus cancer. So, the allele IL1RN*2 and genotype IL1RN2/2 can combine by independent predictors of GERD progression. The study of this field should be continued taking into account not only changes in gastric mucosa, presence of helicobacteriosis, but also the nature of gastroesophageal reflux.
Stomach cancer on the territory of the Far Eastern Federal District
Authors: Gordienko V. P.
Published: November 2020

Objective: General indexes of the disease and death rate among the Far East region due to stomach cancer during the last decade (2008–2017).

Methods: Disease and death rates, statistical reports of patients with oncology and official documents by public health authorities were analyzed.

Results: there were 25,155 new registered cancer cases in Far East region in 2017. It’s 26.6% higher than 10 years ago. 128,776 patients (2.1% of the region population) were under outpatient observation. In the structure of primary morbidity stomach cancer takes the fourth place, and in overall death-rate it’s on the 2nd place, going after trachea, bronchial and lung tumor. The number of patients having I–II phase of stomach cancer had increased from 2008 to 2017, the disease rate among women significantly decreased. The percentage of actively defined cases has increased by several orders for ten years. However the index of accumulation of contingents of the diseased with stomach cancer has decreased. The rate of morphological confirmation of such diagnosis turned out to be lower than the average rate in Russia. The proportion of the diseased registered for 5 years or more has exceeded average numbers. The death rate was the highest during the 1st year of being diagnosed. It can be explained by a very high rate of neglecting.

Conclusions: comparing the increasing number of cancer diseased in Far Eastern Region, the constant decrease of the disease and death rates were noticed at the beginning of the 21st century. This fact can’t be explained by an exact reason now.
Generation of secondary radiation on the surface of endoprostheses used for breast reconstruction during mastectomy, after radiation therapy
Authors: Gulian I. S. , Nikiforova N. O. , Kustov V. N. , Temchenko V. V. , Mandryko A. S. , Nevozhay V. I. , Pankratov I. V. , Matvienko N. A. , Rudyuk V. P.
Published: November 2020

Objective: Experimental estimate of the secondary radiation on the surface of implants and expanders, used for breast reconstruction in case of mastectomy, after making radiation therapy.

Methods: Special equipment was constructed by radiation study department. It consists of linear accelerator as a source of ionizing radiation and a gamma-ray spectrometer with the detector on the basis of ultrapure germanium. The objects of research were the implants and expanders of the different producers.

Results: The maximum amount of the secondary photons on the implants and expanders was generated on the energy level lower than 700 KEV. The level of photons’ generation between 600–300 KEV was higher on the surface of the implants than on the surface of expander filled with saline.

Conclusion: The photons of the secondary radiation with the energy level from 100 to 700 KEV are generated under the influence of ionizing radiation on the implants and tissue expander filled with saline. It can be one of the causes of capsular contractures development after mastectomy.
Kerjasama antara Biro Jasa Travel dengan Rumah Makan Perspektif Maqashid As-Syari’ah
Authors: Qinnatul Khoiroh  , Wawan Juandi
Published: November 2020

In developing a business, a person cannot be separated from the help of others. So that other people become partners in running a business. As the case in Bintang Jaya Abadi Travel Service Agency in Banyuwangi and Ayu Lestari Restaurant in Situbondo. Both of them enter into a cooperation contract in order to promote their businesses. Bintang Jaya Abadi Travel Service Agency wants to progress with the increase in customers or enthusiasts. This is inseparable from the existence of good services and facilities. Likewise, Ayu Lestari Restaurant wants to move forward. The cooperation contract that they do is in writing. However, with other travel service agencies, restaurants also use written cooperation. The cooperation contracts they do are sale and purchase agreements and greetings (orders). The contract between them is in accordance with the shari'ah objective, namely safeguarding property (hifdz al-maal). One form of action that can keep property so that it is used for right actions is the enactment of transactions, meaning that the transactions they carry out are in accordance with the principles of Islamic law.
Penentuan Harga Tiket Pesawat Lion Air Perspektif Hukum Ekonomi Syariah
Authors: Sherly Karlinda
Published: November 2020

Lion Air is a private company engaged in air transportation. It uses a low-cost concept “Low-Cost Carrier” with the slogan “We Make People Fly”. Airline ticket prices sold on Lion Air airline sites and travel agents often experience significant fluctuations. It can be seen in certain moments, such as Eid, long holidays, and other holidays. This study uses a descriptive qualitative approach. This research is research using a field approach in the form of primary data and secondary data. Meanwhile, data sources obtained using observation, interviews, and documentation. Then analyzed descriptively through, reduction, display and conclusion and prescriptive. The implementation of the principle of determining Lion Air ticket prices includes transactions between airlines and consumers, airlines with travel agents, and travel agents with consumers. The transaction in fiqh is classified as an ijarah contract. The second implementation is related to the ticket component which is closely related to fluctuation. Fluctuations caused by the law of normal supply and demand may have consequences, while fluctuations that occur due to company play are categorized as gharar.
Rekonstruksi Tujuan Pendidikan Islam: Studi Komparasi Pemikiran Majid Irsan al-Kilani dan Ahmad Dahlan
Authors: Ramadhan Ossi Marga
Published: November 2020

The process of education always goes through dynamic stages. It always adapts to the atmosphere of the students' conditions and current development. Therefore the reconstruction of Islamic education’s purpose is very important. Especially during the era of al-Kilani and Ahmad Dahlan, both of them met their respective concerns so that they thought to modify and to change Islamic education’s purpose. This article aims to find the standpoint of their version of Islamic education’s purpose. It was library research that referred to the sources of related literature and was processed using comparative descriptive analysis. The finding showed that there were similarities between them, such as first, the similarity in the setting of purpose formulation. Second, there were also similarities in the basic foundation for their educational purpose which are Al-Qur'an and Al-Hadith. However, there were a few differences from their standpoint such as in aspects of educational background and intellectual heritage.
AVALIAÇÃO DE FERIDAS CUTÂNEAS EM JUMENTOS TRATADAS COM POMADA À BASE DE EXTRATO DE AMEIXA-BRAVA A 10%
Authors: Souza Juliany Alves de , Bezerra Francisco Ermerson Ferreira , Gonçalves José Bruno Landim , Moura Maria Francicarla Nascimento , Ramos Luís Carlos Estrela , Felix Naianne Araújo , Beltrão Eduardo Santiago , Knupp Sheila Nogueira Ribeiro
Published: November 2020

:  Objetivou-se com este trabalho avaliar feridas cutâneas em jumentos tratadas com pomada à base de Ximenia americana (ameixa-brava) 10%. Foram utilizados sete asininos adultos, machos, da raça nordestina. Os mesmo animais foram submetidos a dois tipos de tratamentos distintos, o tratado e o controle, utilizando-se uma ferida em cada hemitórax. Foram avaliados parâmetros macroscópicos e medidas das áreas das feridas. Também foi calculado o percentual de contração das feridas. Durante a inspeção dos parâmetros macroscópicos, não foi observada diferença entre os grupos. Na avaliação do percentual de contração das feridas o grupo tratado mostrou uma discreta maior contração. A partir dos resultados obtidos conclui-se que a pomada à base de extrato de ameixa-brava a 10% não demonstrou capacidade de acelerar o processo cicatricial.
ABSCESSO CUTÂNEO ÚNICO EM CÃO PORTADOR DE HEPATOZOONOSE SUBCLÍNICA
Authors: Fernandes Mikaelly Mangueira , Sousa Larissa Do Nascimento , Nascimento Kenikywaynne Kerowaynne Felix do , Silva Juliana Trajano da , Ferreira Larissa Claudino , Duarte Amélia Lizziane Leite , Knupp Sheila Nogueira Ribeiro
Published: November 2020

O Hepatozoon canis é um protozoário que causa doença em cães através da ingestão de carrapatos infectados. A sintomatologia varia desde uma forma subclínica, em cães aparentemente sadios, até uma doença debilitante severa. O presente estudo tem por objetivo relatar a ocorrência de infecção subclínica por Hepatozoon sp. associada à presença de abscesso cutâneo. O cão apresentou infecção no tecido cutâneo após atividade de caça e possivelmente um traumatismo na região; apesar da avaliação hematológica normal da série vermelha no primeiro atendimento clínico. O envolvimento do gênero Hepatozoon foi confirmado apenas após repetição do hemograma. Sugere-se que imunossupressão gerada pela hepatozoonose subclínica possibilitou a ocorrência da infecção cutânea caracterizando um processo infeccioso neste paciente
CARCINOMA EM TUMOR MISTO EM CADELA: RELATO DE CASO
Authors: Matias Isabela Calixto , Oliveira Matheus Carlos de , Santos Tielly Geovana Lourenço , Oliveira Flaviane Neri Lima de , Araújo Ana Lucélia de , Santana Vanessa Lira de , Dantas Antônio Flávio Medeiros , Maia Lisanka Ângelo
Published: November 2020

Descreve-se um caso de carcinoma em tumor misto em uma cadela de sete anos de idade atendida no HV-ASA do IFPB, com histórico de crescimento de um nódulo há mais de nove meses. No exame clínico notou-se apatia, escore corporal ruim, aumento de linfonodos e massa de aproximadamente 25x17x10 cm de extensão em mama torácica esquerda, de consistência firme, ulcerada e drenando conteúdo piosanguinolento. Foi então realizado processo cirúrgico de nodulectomia e encaminhamento para biópsia e avaliação histopatológica. Macroscopicamente observou-se massas multilobuladas, encapsuladas, de coloração amarelada a amarronzada com presença de cavitações. Microscopicamente notou-se projeções papilares em meio a estroma fibrovascular e porção mesenquimal composta por tecido ósseo, caracterizando carcinoma em tumor misto.
ENDOCARDITE EM SUÍNOS NA REGIÃO SEMIÁRIDA DA PARAÍBA
Authors: Soares Laynaslan Abreu , Ramos Maria Estrela de Oliveira , Nóbrega Matheus Estrela Sulpino da , Durand Vitória Rodrigues , Alves Davi Nogueira Maciel , Borges Ismael Lira , Galiza Glauco José Nogueira , Maia Lisanka Ângelo
Published: November 2020

Descreve-se dois casos de endocardite em valva atrioventricular esquerda (VAE) em suínos provenientes da Suinocultura do IFPB. Relatou-se que o suíno A apresentava sintomatologia nervosa e o suíno B cianose de extremidades e tosse seca. Macroscopicamente, foi observado material amarelado, friável e de superfície irregular, ocluindo parcialmente o orifício da VAE dos suínos. Histologicamente, apresentavam área focalmente extensa de deposição acentuada de material eosinofílico, fibrilar a condensado, associado a infiltrado inflamatório neutrofílico e miríades bacterianas cocóides basofíllicos aderidos ao endocárdio. Com base nos achados clínicos, epidemiológicos e patológicos realizou-se o diagnóstico de endocardite bacteriana, no suíno A como achado de necropsia e o suíno B como causa de insuficiência cardíaca congestiva aguda (ICCA). 
FIBROMA EM EUPSITTULA CACTORUM NO SERTÃO PARAIBANO
Authors: Alves Paula Manuela de Miranda , Silva Caroline Gomes da , Oliveira Leonardo Vinícius Silva de , Santos Renata Arruda dos , Firmino Millenade Oliveira , Araújo Ana Lucélia de , Santana Vanessa Lira de , Maia Lisanka Ângelo
Published: November 2020

Relata-se um caso de fibroma em Eupsittula cactorum proveniente do município de Sousa. Foi atendido no HVASA-IFPB, um psitacídeo, macho, com sete anos de idade,que apresentava um nódulo cutâneo na asa direita, aderido ao osso. Após a remoção cirúrgica por nodulectomia, observou-se um nódulo com área avermelhada e ulcerada, e ao corte a superfície com tecido amarelado e friável. Microscopicamente, observaram-se células fusiformes distribuídas em feixes aleatórios e em redemoinhos com citoplasma moderado e eosinofílico, com núcleos alongados, cromatina frouxa à condensada e nucléolos evidentes, além de áreas multifocais de hemorragia. Com base nos achados clínicos, macroscópicos e microscópicos realizou-se o diagnóstico de fibroma.Apesar de ser uma neoplasia comum em psitacídeos, não há trabalhos caracterizando-o no sertão paraibano.
ENTERITE GRANULOMATOSA EM UM CÃO
Authors: Silva Caroline Gomes da , Soares Laynaslan Abreu , Matias Isabela Calixto , Araújo Ana Lucélia de , Knupp Sheila Nogueira Ribeiro , De Oliveira Flaviane Neri Lima , Dantas Antônio Flávio Medeiros , Maia Lisanka Ângelo
Published: November 2020

Relata-se um caso de um cão com enterite granulomatosa, proveniente da zona rural de São João do Rio do Peixe, que possuía o hábito de nadar em açude. Foi atendido na CMPA do HVASA-IFPB, campus Sousa, apresentando emagrecimento progressivo, hematoquezia e presença de massa em região hipogástrica. Na laparotomia exploratória, constatou-se espessamento de alças intestinais e aumento de linfonodos mesentéricos, sendo coletado fragmento de colón descendente através de biópsia incisional. Microscopicamente foram observadas imagens negativas de estruturas tubuliformes em áreas de necrose e de infiltrado inflamatório neutrofílico e histiocítico. No exame imuno-histoquímico não houve marcação positiva para o Pythium insidiosum. Com base nos achados clínicos, epidemiológicos e patológicos realizou-se o diagnóstico de enterite granulomatosa.
HAMARTOMA COLAGENOSO EM CÃO
Authors: Padilha Mayla De Lisbôa , Melo Lídio Ricardo Bezera de , Neto Pedro Barosa de Brito , Brito Angélica Fernandes Rodrigues de , Silva Leonardo De Barros , Monteiro Nayanny Morais de Oliveira , Campos Édipo Moreira , Lima Telma De Sousa
Published: November 2020

Hamartoma são lesões tumorais oriundas de um crescimento excessivo de estruturas normais aolocal em que naturalmente se encontram, a qual pode ocorrerem qualquer tecido ou órgão. Um canino, macho, 10 anos da raça Pitbull foi atendido com queixa principal de aparecimento de nódulos na região abdominal. Ao exame físico o animal apresentava três lesões nodulares de tamanhos variados na região abdominal. O animal foi encaminhado para realização de biopsia excisional. No exame histopatológico foi observada massa tumoral não encapsulada composta por denso feixe de fibras colágenas bem arranjadas na derme. Com base nos dados anatopatológicos e histopatológico, o diagnóstico foi de hamartoma colagenoso e o procedimento cirúrgico foi curativo.
PAPILOMATOSE PENIANA EM EQUINO
Authors: Melo Lídio Ricardo Bezerra de , Souto Erick Platini Ferreira de , Padilha Mayla De Lisbôa , Assis Daniel De Medeiros , Alves Rodrigo Cruz , Correia Gabriel Da Silva , Neto Eldinê Gomes De Miranda , Dantas Antônio Flávio Medeiros
Published: November 2020

Papilomas são neoplasias cutâneas benignas, tendo aparência de couve-flor. Objetivou-se descrever um caso de papilomatose peniana, baseada em achados clínicos e anatomopatológicos em equino castrado. Um equino de 15 anos, 350 kg, foi atendido por um médico veterinário apresentando lesões nodulares e crostosas em pênis e prepúcio e parafimose. O animal foi encaminhado à Clínica Médica e Cirúrgica de Grandes Animais do HV/UFCG, Campus de Patos-PB, para a realização da amputação do pênis. Na avaliação histológica do produto da penectomia observaram-se proliferações de ceratinócitos com aspecto digitiforme e foi estabelecido o diagnóstico de papilomatose peniana. Conclui-se que a proliferação dos papilomas no prepúcio e pênis do equino desencadeou um quadro de parafimose e consequente amputação do pênis, melhorando a sobrevida do animal.
DIABETES MELLITUS ASSOCIADO A NEOPLASIA MAMÁRIA E OUTROS FATORES EM CÃO – RELATO DE CASO
Authors: Oliveira Susana Pereira de , Araújo Sandy Beatriz Silva de , Landim Camila Pontes , Dias Diane Cristina de Araújo , Filho Ewerton De Medeiros
Published: November 2020

A diabetes mellitus é uma doença sistêmica causada pela falta relativa ou absoluta de insulina. Suas complicações crônicas são as principais causas da morbidade e mortalidade. O objetivo deste trabalho foi relatar um caso de diabetes mellitus em cadela com neoplasia mamária. Na anamnese, foi relatado polifagia, poliúria, polidipsia, perda de peso e cegueira. No exame físico, foi constatado nódulo mamário na região torácica cranial esquerda, o qual foi caracterizado como neoplasia benigna. Foram solicitados exames complementares para a confirmação do diagnóstico. O animal foi então diagnosticado com diabetes mellitus, havendo indícios de demais acometimentos e endocrinopatias possivelmente correlacionadas. Optou-se pela mastectomia unilateral esquerda e controle da diabetes por insulinoterapia e dieta com ração formulada para diabéticos.

 

 

 

Palavras-chave: endocrinopatias; complicações crônicas; doença sistêmica.
PRINCIPAIS OCORRÊNCIAS DE LESÕES EM FRANGOS NO ABATEDOURO DO INSTITUTO FEDERAL DE EDUCAÇÃO CIÊNCIAS E TECNOLOGIA (IFCE) CAMPUS IGUATU-CE.
Authors: Oliveira Francisco Thiago Vieira , Coelho Antônio Alison da Costa , Silva Teresa Cristina da Paixão , Araújo Luenny Carla Silva dos Santos Carvalho de
Published: November 2020

A produção brasileira de carne de frango é destaque no cenário mundial, sendo o segundo maior produtor e o primeiro exportador, porém abates clandestinos ainda são realidades. Objetivo descrever as principais lesões em frangos no abatedouro frigorifico do IFCE-Iguatu-CE, no período de 09 de janeiro a 19 outubro de 2017. As atividades realizadas no abatedouro de aves foram, o acompanhamento da avaliação anti-morteme post-mortem. Foi observado que as lesões que as carcaças, órgãos e vísceras apresentavam eram semelhantes. Condenações mais comuns: fígado, lesões traumáticas, descarte total e pés com calosidades, possuindo alterações de coloração, consistência e textura. Portanto, as similaridades entre as lesões encontradas, o destino e decisões tomadas quanto ao produto final é diferente.
HEMANGIOSSARCOMA EM UM CÃO
Authors: Oliveira Flaviane Neri Lima de , Soares Karoline Lacerda , Ramos Fernanda Ramalho , Leite Ialys Macêdo , Borges Olívia Maria Moreira , Souza Almir Pereira de , Galiza Glauco José Nogueira de , Dantas Antônio Flávio Medeiros
Published: November 2020

Hemangiossarcomas são neoplasias malignas oriundas do endotélio vascular com alto índice metastático que acometem com maior frequência os cães de meia idade. Objetivou-se com esse trabalho descrever um caso de um canino, SRD, macho, de sete anos de idade que morreu durante atendimento clínico e foi encaminhado para o Laboratório de Patologia Animal da referida instituição. Ao exame necroscópico verificaram-se aderências entre fígado, baço, estômago e omento. O fígado apresentava-se difusamente mais pálido e com massas vermelho-amareladas multifocais, de diferentes tamanhos e consistência flácida, distribuídas aleatoriamente na superfície capsular de todos os lobos que, ao corte, se aprofundavam ao parênquima. O diagnóstico de hemangiossarcorma multicêntrico foi estabelecido com base nos achados anatomopatológicos.
ANAPLASMOSE BOVINA – RELATO DE CASO
Authors: Paiva Ruana Rafaela Lira Torquato , Costa Orlandina Alves da , Marques Íris Silva , Silva Bismark Alves da , França Alex Carlos da Silva , Mayer Leonardo Lomba , Seal Desirée Coelho de Mello , Dias Regina Valéria da Cunha
Published: November 2020

Anaplasmose é uma enfermidade parasitária causada pela rickettsia intraeritrocítica Anaplasma marginale, queprovoca grande impacto econômico na produção de gado em muitos países. Sua transmissão pode ser feita por carrapatos, por via transplacentária, de forma iatrogênica ou por vetores mecânicos como moscas hematófagas e mutucas. A infecção é causada pelo desenvolvimento e multiplicação do parasita nas células sanguíneas e tem como principais sinais clínicos febre, anemia, icterícia, anorexia e prostração. O objetivo deste trabalho foi descrever um caso de anaplasmose em um touro, Gir, de dois anos de idade, pesando 450 kg, com intuito de esclarecer a respeito da importância do diagnóstico laboratorial e do acompanhamento do animal com sucessivos exames de sangue, visando um tratamento adequado e prognóstico favorável.
INFESTAÇÃO POR Felicola subrostratus EM FELINO: RELATO DE CASO
Authors: Pereira Paulo Douglas Gomes , Beserra Lucas Alencar Fernandes , Mariz Mateus Linhares de Almeida , Batista Samara Tereza Moraes , Azevedo Maria Emília Ferreira de , Lima Djvan Vieira , Sousa Almir Pereira de
Published: November 2020

Felicola subrostratus é um ectoparasito específico de felinos de distribuição mundial e infestação incomum. São mastigadores, cuja infestação, geralmente, é observada na face, e na região dorsal. Em geral, os sintomas incluem inquietação, prurido com seborreia, alopecia, escoriações e infecções bacterianas secundárias. O diagnóstico da pediculose pode ser realizado através da visualização direta do piolho e microscopia. Para o tratamento, inclui-se a utilização de ivermectina, selamectina, Fipronil e inseticidas. O objetivo deste trabalho foi relatar um caso de infestação F. subrostratus em um felino atendido no Hospital Veterinário da UFCG, Patos-PB, macho, SRD, não castrado e com 1 ano de idade. A queixa principal era de que o animal apresentava prurido intenso há 15 dias. No exame físico foram encontradas áreas de hipotricose na região abdominal e torácica, presença de ectoparasitas e mucosas levemente pálidas, temperatura retal 37,9°C, frequência cardíaca 176 bpm, frequência respiratória 40 mpm, escore corporal 3 (1-5), tugor cutâneo 2”, TPC 2”, linfonodos e ausculta cardiopulmonar sem alteração. O diagnóstico foi realizado por meio de cultura fúngica e tricograma. O tratamento foi realizado com utilização de anti – histamínico a base clemastina (Alergovet C) VO/BID por 7 dias, e aplicação tópica de Revolution®6%, no dorso do animal. A infestação por F. subrostratus em felino representa uma enfermidade pouco comum nessa espécie, estando associada principalmente com aglomerações, sendo de fácil diagnóstico e bom prognóstico quando tratada adequadamente.
CRIPTOCOCOSE NASAL EM CÃO: RELATO DE CASO
Authors: Pereira Paulo Douglas Gomes , Guedes Hitalo De Araújo , Mariz Mateus Linhares de Almeida , Azevedo Maria Emilia Ferreira de , Beserra Lucas Alencar Fernandes , Oliveira Maria Cristina Cordeiro de , Brito Larissa Keyla Fernandes , Gomes Tallyson Medeiros
Published: November 2020

A criptococose é uma doença fúngica multissistêmica de caráter oportunista, de ocorrência mundial, que acomete o homem e vários animais. A via mais frequente de contaminação é a inalatória, com posterior colonização do trato respiratório superior, podendo atingir os alvéolos e desenvolver a sintomatologia respiratória, ou ocorrer disseminação hematógena com possível comprometimento do sistema nervoso central. Foi atendido na Clínica Saúde Animal, Pombal – PB, um cão, macho, sem raça definida (SRD), 6 anos de idade, apresentando lesão ulcerativa em região nasal há mais de 30 dias, com histórico de tratamento anterior sem melhora clínica. Através do exame citológico chegou –se ao diagnóstico de Cryptococcus sp. Com a instituição do tratamento, o animal apresentou melhora clínica e regressão da lesão ao final do mesmo.
Facilitating difficult discussions in STEM
Authors: Goldsmith Gregory , Gormally Brenna M.G. , Green Rebecca , Harrison Aaron W. , Hoover Brian A. , Quides Kenjiro , Thammavongsy Zachary , Welles Shana R. , Zhang Bingjie , Gray Kelsey M.
Published: November 2020

Discussion can be an important and powerful tool in efforts to build a more diverse, equitable, and inclusive future for STEM. However, facilitating discussions on complex and uncomfortable issues, like racism and sexism, can feel daunting. We outline a series of steps that can be used in offices, laboratories, and classrooms to facilitate productive discussions that empower everyone to listen, contribute, learn, and ultimately act to transform STEM.
Quantifying ‘promising trials bias’ in randomized controlled trials in education
Authors: Sims Sam , Anders Jake David , Inglis Matthew , Lortie-Forgues Hugues
Published: November 2020

Randomized controlled trials have proliferated in education, in part because they provide an unbiased estimator for the causal impact of interventions. It is increasingly recognized that many such trials in education have low power to detect an effect, if indeed there is one. However, it is less well known that low powered trials tend to systematically exaggerate effect sizes among the subset of interventions that show promising results. We conduct a retrospective design analysis to quantify this bias across 23 promising trials, finding that the estimated effect sizes are exaggerated by an average of 52% or more. Promising trials bias can be reduced ex-ante by increasing the power of the trials that are commissioned and guarded against ex-post by including estimates of the exaggeration ratio when reporting trial findings. Our result also suggest that challenges around implementation fidelity are not the only reason that apparently successful interventions often fail to subsequently scale up. Instead, the findings from the initial promising trial may simply have been exaggerated.
Apparent Nutrient Digestibility and Carcass Yield of Broiler Chickens Fed Cooked Shea Nut Cake Diets of Different Fermentation Periods
Authors: AYODEJI ADEBAYO OLAOLUWA , CHIKEZIE JUDE , KILISHI HALIDU SHAFIU
Published: November 2020

Cake of shea nut is an agroforestry by-product and residue after fat extraction from shea nuts for fat with no economic value and its increasing output has become an environmental issue lately. A 30-day study was conducted to investigate the apparent nutrient digestibility and carcass yield of broiler chicken fed cooked cake of shea nut diets of different fermentation periods. A total of 144 unsexed Arbor Acres Plus day-old broiler chickens were divided into four dietary treatments with four replicates of nine birds each in a completely randomized design. The results showed that fermentation enhanced the nutrient profile of cake of shea nut meal especially concerning crude protein and crude fiber as compared to raw cake of shea nut meal. The treatment values for crude protein and crude fiber digestibility showed significant (p < 0.05) differences amongst the dietary treatments while other nutrient parameters measured were not significantly (p > 0.05) different. There was no significant (p > 0.05) difference amid the treatment means for the control (carcass, breast and liver yield) and the carcass, breast and liver yield of broiler chickens fed diets containing different periods of fermented-cooked cake of shea nut meal.
Tl-concentration dependence of scintillation properties in Tl-doped CsBr single crystals
Authors: Takahashi Kentaro , Kimura Hiromi , Nakauchi Daisuke , Kato Takumi , Kawaguchi Noriaki , Yanagida Takayuki
Published: November 2020

Photoluminescence and scintillation properties of CsBr single crystals with various concentrations of Tl (0.1%, 0.2%, 0.3%, 0.5% and 1%) were examined. Under an excitation at 260–280 nm and X-ray excitation, all the samples exhibited emission peaking around 360 and 510 nm with the decay time constants of μs order. The former emission would be due to 3P1 → 1S0 transitions of Tl+ ion associated with tetragonal structures, and the latter one was due to off-center configurations of self-trapped excitons localized near Tl+ ions at trigonal structures. The pulse height analysis under 137Cs γ-ray (662 keV) irradiation indicated that the 0.3%Tl-doped sample possessed the highest scintillation output among the prepared samples. From the results under various γ-ray irradiation, we confirmed that the scintillation output showed a good proportional response against γ-ray energy up to 1274 keV.
Low-energy cross-sectional cathodoluminescence analysis of the depth distribution of point defects in Si-ion-implanted β-Ga2O3
Authors: Sugie Ryuichi , Uchida Tomoyuki , Hashimoto Ai , Akahori Seishi , Matsumura Koji , Tanii Yoshiharu
Published: November 2020

Low-energy cross-sectional cathodoluminescence (CL) with a beam energy of 1 keV was applied to Si-ion-implanted β-Ga2O3 (−201) wafers to investigate implantation damage and recovery. The semi-quantitative CL-intensity depth profiles were obtained by considering nonradiative recombination at the surface. We found that the CL intensity did not fully recover, even after annealing at 1273 K. Such insufficient recovery was prominent in the Si-diffusion region, suggesting that Si-dopant activation and Si diffusion are strongly correlated through interaction with point defects generated by implantation, such as Si interstitials and Ga vacancies.
BILATERAL BREAST CANCER - CASE SERIES
Authors: Murugesan N. , Amudhan M. , Viswanathan M.S. , Bhanumati Bhanumati , Muthuraj Muthuraj , Gajendran Gajendran , Sundaram P.N. Shanmuga
Published: November 2020

This is a presentation of four rare and interesting cases of bilateral breast cancer. The cases vary from Synchronous double primary carcinoma breast, bilateral infiltrating ductal carcinoma, bilateral synchronous metastatic carcinoma and metachronous breast carcinoma. The incidence of developing either primary or metastatic carcinoma in the other breast is increased in patients who already have carcinoma in one side and mammography contributes greatly to the detection of these lesions. (1) It is of significant prognostic value and important in deciding the clinical management based on the classification whether it is a primary or a secondary lesion.
EVALUATION OF OUTCOME OF MEDIAL OPENING WEDGE HIGH TIBIAL OSTEOTOMY FOR UNICOMPARTMENTAL KNEE OSTEOARTHRITIS
Authors: Shewale R. N. , Khatri Ketan J.
Published: November 2020

Background: Osteoarthritis is often found in weight-bearing joints, the knee being the most common site. Most patients of symptomatic osteoarthritis of knee are associated with varus malalignment that is causative or contributory to painful arthritis. Correcting the malalignment of the knee relieves symptoms by transferring the functional load to the unaffected compartment. The goal of the treatment is to relieve medial compartment knee pain and slow down the arthritic progression. We report the outcome of a simple technique of medial opening wedge high tibial osteotomy in treating the medial compartment osteoarthritis of the knee.
Materials and method: A prospective interventional study was carried out over a period of 2 years from November 2017 to October 2019 in a sample size of randomly selected 41 patients having unilateral knee osteoarthritis. All patients after a proper preoperative assessment underwent high tibial osteotomy and the outcome was evaluated using knee society scoring system.
Results: The age of the patients ranged from 40 – 65 years with a mean age of 51 years, 13 were males and 28 were females showing female predominance (68.2%). The mean knee score and the mean functional score of the patients before surgery were 60 and 61.95 respectively and post operatively at the end of 6 months the knee score and functional score was 77 and 80.53 respectively. By the end of 6 months out of 41 patients, 12 patients (29.2%) had excellent functional outcome, 18 patients (43.90%) had good functional outcome, 09 patients (21.95%) had fair functional outcome while only 02 patients (04.87%) had poor functional outcome.
Conclusions: The present study shows that HTO is a good option in isolated medial compartment OA of knee. Significant increase in the knee score and functional score was found after high tibial osteotomy for the patients of osteoarthritis with varus deformity. Success of high tibial osteotomy relies on appropriate patient selection, proper osteotomy type and precise surgical technique.
IMPACT OF COVID 19 ON ENVIRONMENT AND NATURAL RESOURCES: AN OBSERVATIONAL STUDY
Authors: Kaura Sameer , Taneja Ashima , Garg Kamakshi , Kaur Gagandeep , Handa Surbhi , Kaur Harmeet , Gupta Sakshi , Kaur Anmol , Verma Hitesh , Singh Robin
Published: November 2020

The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID 19), caused by severe acute respiratory syndrome coronavirus 2(SARS CoV 2). COVID-19 needs to be seen beyond just the number of cases or deaths, especially in the context of its impact on air pollution, decline in road traffic accidents, improvement in air and water quality, decline in respiratory infection, nosocomial infections and pediatric chest infections, though some negative effect can be seen on the physical activity and hospital related transmission of COVID-19 to healthcare workers. An invisible virus has shown that it is possible that tangible policies can make world a better place to live in.
RAPID URINE TRYPSINOGEN-2 DIPSTICK ASSAY TO DIAGNOSE ACUTE PANCREATITIS IN EMERGENCY SETUP
Authors: S Shankar. , C Kolandasamy. , P Srinivasan.U. , L. Naganath babu O.
Published: November 2020

Background: Early diagnosis of acute pancreatitis remains a challenge in emergency set up. The early management results in better outcomes but none of the available investigations were rapid and accurate to guide the management in these patients. Hence in suspected cases of acute pancreatitis, the urinary trypsinogen 2 dipstick assay can be used to diagnose them at the earliest in the Emergency setup. The purpose of this study is to determine the accuracy of urine trypsinogen 2 assay in diagnosing acute pancreatitis.
Methods: The patients presenting with symptoms consistent with acute pancreatitis to the emergency department, at a tertiary care hospital in Southern India between November 2018 to November 2019 were included in a prospective observational study after obtaining Institutional ethical committee clearance. In addition to the routine investigations done in cases of acute abdomen, patients underwent urine trypsinogen 2 dipstick test. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) were calculated. Results were compared.
Results: A total of 50 cases were included in the study. The urine trypsinogen 2 dipstick test was positive in 35 of 37 patients with acute pancreatitis (sensitivity, 94.59%) and in none of 13 patients with abdominal pain but without any evidence of acute pancreatitis (specificity, 100%). The diagnostic accuracy of the urine trypsinogen 2 dipstick test was 96% in this study higher than other conventional laboratory investigations.
Conclusion: This study shows that the dipstick test has high diagnostic accuracy and can be considered for regular use for diagnosing pancreatitis along with the conventional methods.
EFFECT OF DUTASTERIDE (5 ALPHA-REDUCTASE INHIBITOR) TREATMENT ON REDUCING BLOOD LOSS, IN PERIOPERATIVE PERIOD OF OPEN PROSTATECTOMY DONE IN LARGE PROSTATE.
Authors: Goel Rahul
Published: November 2020

Objective- Open prostatectomy (OP) is still a very valid option in treatment of very large volume prostates in the absence of holmium laser enucleation ( holmium laser is a rarity and expensive in govt and self funded medical colleges), its main complication being intra and perioperative bleeding. Preoperative use of dutasteride has shown to decrease perioperative bleeding in TURP (transurethral resection of prostate), though till date OP being a standard procedure in large prostate management ,there is no study showing effect of dutasteride in perioperative bleeding in OP. The aim of this study was to evaluate whether pretreatment with dutasteride for 6 weeks before OP could reduce blood loss in surgery, as high watt holmium laser is still not available in most of the medical colleges ,treating patients for free .
Material and Methods- Data of 218 patients who underwent OP for BPH (benign prostatic hyperplasia), were investigated retrospectively. Of 218 patients ,46 were pretreated with dutasteride for 6 weeks and the rest were not under dutasteride treatment. Age, prostate volume , prostate specific antigen(PSA) levels, coagulation profile, platelet count, pre and post operative hemoglobin(Hb) levels ,and blood transfusion history were recorded .Blood loss was estimated as follows : pre operative Hb(-) post operative Hb(+) amount of blood transfusion. The 2 groups were compared by independent samples t-test and a p value of 0.05 was considered significant.
Results- The groups were similar in terms of age , prostate volume ,platelet counts, coagulation tests and post operative Hb levels. Preoperative Hb levels were lower in dutasteride group (13.4 vs 14.3,p=0.002) and amount of bleeding (-2.72g/dl vs.-1.93g/dl, p=0.01) was shown to be significantly lower in dutasteride group.
Conclusion -Our result showed that pretreatment with dutasteride for 6 weeks before OP for very large prostates, reduces perioperative bleeding , and can be used in medical colleges where treatment is free ,instead of using holmium laser, though further prospective randomized trials would support the effectiveness of such treatment.
Reproductive performance of the larger grain borer Prostephanus truncatus (Horn) (Coleoptera: Bostrichidae) on three different food hosts
Authors: Sadiku B.T , Kemabonta K.A , Makanjuola W.A
Published: November 2020

The reproductive performance, damage and weight loss of the Larger Grain Borer (LGB), Prostephanus truncatus (Horn) (Coleoptera: Bostrichidae) on three food hosts namely cassava (TMS 30572, TME 419 and TMS98/0505), maize (SUWAN-1-SR-Y, BR 9943-DMR-SR and 2009 TZEWDT STR) and wood (Albizia glaberrima, Gmelina arborea and Tectona grandis) were investigated. Samples of 100g of the food host were weighed in four replicates into 250ml Kilner® jar and infested with 10 pairs of 1-5 day old LGB. The developmental period of LGB on each of the food host was noted and recorded. Similarly, weight loss and weight of damaged grains was determined as basis for determining the susceptibility of the food hosts to LGB infestation. Proximate composition of infested and un- infested food hosts of LGB were determined following the analytical procedures. Maize was the most preferred host, followed by cassava as indicated by the high number of adult LGB and grain damage recorded on them. The development of LGB was completed on all maize and cassava varieties but not on any of the wood species examined. Percent damage, weight loss, and percent dust were significantly (P<0.05) different among the food hosts. The mean percent damage (79.0), percent weight loss (57.0) and percent dust (25.0) recorded in cassava variety-TMS30572 was significantly (p<0.05) higher than on other food hosts. No weight loss was recorded on T. grandis. This study revealed the ability of P. truncatus to breed and feed on the maize and cassava varieties with no evidence of breeding on the three wood species. Carbohydrate contents were higher in the most preferred food host, maize (70.91) and less preferred food, cassava (82.02) than non-preferred wood species (13.56), indicating that carbohydrate was an essential component in most preferred food. Infestation of LGB caused significant reduction (P<0.05) in the nutritional component of the food hosts. This study showed that LGB still remains an economically important insect pest of maize and cassava. Considering the importance of these two crops to the livelihood of smallholder farmers, appropriate monitoring and control measures should therefore be put in place to safe guard maize and cassava from the ravages of this pest for the attendant enhancement of food security in Nigeria.
Influence of Vitellaria Paradoxa Gaertn Depletion on the Incidence, Abundance and Distribution of Cirina Forda Westwood (Lepidoptera: Saturniidae) in Niger State, Nigeria
Authors: Muhammad M. I. , Ande A. T.
Published: November 2020

The pallid emperor moth, Cirina forda, is a prominent edible insect in Niger State but currently at great risk of extinction. The incidence, abundance and distribution of Cirina forda, was investigated for four consecutive seasons, i.e. May-June 2010, 2011, 2012 and 2013 to ascertain the effect of the depletion of its host plant, Shea butter trees, Vitellaria paradoxa. in Niger State, Nigeria. C. forda egg clusters located on the host plants were enumerated to ascertain the seasonal abundance by visual counting using hand lenses and binoculars (MARCO-model 750/8 m-988000 m). At each location, 100m2 land area in which three 10m2 portions were mapped as replicate sites, were investigated for host plant density, egg cluster abundance and distribution within three host plant canopy height ranges. The 41 locations in six Local Government Areas (LGAs) where C. forda occurred in Niger State in 2010 were investigated. The result indicated the GPS of each of the locations and showed that Niger state had a very rich but fast dwindling population of V. paradoxa. C. forda egg cluster abundance across the six LGAs showed Niger state as highly endowed but ephemeral and highly unpredictable, especially in terms of location where they occurred. The egg cluster abundance reduced drastically from 58.1± 12.1 and 56.1±24.1 egg cluster/host plant in 2010 and 2011, respectively to 41.3 ± 8.3 and 29.7 ±5.1 egg cluster/host plant in 2012 and 2013 cropping seasons, respectively. Locational similarities were observed in the trends of C. forda host plant density reduction and egg cluster abundance over the four cropping seasons and these were corroborated across the State. The decreasing densities of Shea butter trees was identified as posing serious threats to egg laying by C. forda. The possibility of the extinction of C. forda was identified as imminent and a conservation approach that stems the indiscriminate destruction of host tree, V. paradoxa (Shea butter trees) was proposed.
DevOps In Embedded Systems Domain
Authors: R Radhika
Published: November 2020

This is a point of view of Devops in embedded domain
Perancangan Interval Perawatan Mesin Secara Preventive Maintenance Dengan Metode Reliability Centered Maintenance ii (rcm ii) Studi Kasus : Pt. Gunung Selamat Lestari
Authors: Roganda Simbolon  , Doarjo Simbolon  , Paris Johannes Ginting
Published: November 2020

PT.Gunung Selamat Lestari merupakan perusahan yang bergerak dibidang produksi CPO dan kernel, perusahan ini sering mengalami kendala dalam memaintenance mesin produksi. Penelitian ini mencoba melakukan analisis terhadap permasalahan tersebut dan memberikan usulan perbaikan. Adapun metode atau tools yang digunakan dalam penelitian ini adalah FMEA dan Reliability Maintenance II (RCM II), metode ini digunakan untuk menetukan kegiatan dan interval perawatan berdasarkan pada RCM II Decision Worksheet sesuai dengan fungsi dan sistem dari mesin dan FMEA digunakan untuk mengidentifikasi penyebab kegagalan serta fek yang ditimbulkan dari kegagalan tersebut. Dengan perhitungan interval perawatan diperoleh perawaratan usulan dengan mempertimbangkan waktu kegagalan, hasilnya adalah komponen flexibel coupling selama 262 jam, liner cylinder selama 316 jam, dan steer arm selama 246 jam. Dengan kondisi ini maka terlihat jelas bahwa penerapan Reliability Centered Maintenance II lebih efisien, maka diharapkan perusahaan dapat menggunakan metode ini untuk diimplementasikan dalam kegiatan perawatan.
Rancangan Perbaikan Stasiun Kerja Di Pt Karsa Wijaya Pratama Dengan Menggunakan Metode Plibel Checklist Dan Qec (Quick Exposure Check)
Authors: Putri Pertiwi  , Zeny Fatimah Hunusalela
Published: November 2020

PT Karsa Wijaya Pratama merupakan industri yang bergerak pada bidang otomotif beberapa aktivitas yang dilakukan menggunakan mesin produksi yang manual, Berdasarkan pengamatan permasalahan yang timbul pada perusahaan tersebut yang menyebabkan resiko pada pekerjaan disebabkan postur tubuh pekerja yang tidak sesuai dengan standar. Penelitian diawali dengan mengetahui permasalahan dan menilai postur kerja dengan kuisioner PLIBEL Checklist dan Quick Exposure Check (QEC). Berdasarkan hasil rekapitulasi keseluruhan dengan metode PLIBEL Checklist nilai pada operator cutting sebesar 66,66% sedangan pada operator Finishing sebesar 44,44%. Pada metode Quick Exposure Check rekapitulasi resiko terbesar pada bagian punggung, bahu dan pergelangan tangan sebesar 72,15% untuk operator cutting, sedangkan operator finishing sebesar 55,11% sehingga dari hasil rekapitulasi perlu adanya perbaikan pada stasiun kerja masing-masing operator. Hal ini menunjukan perlu diadakan nya penelitian lebih lanjut dan dilakukan suatu perubahan pada stasiun kerja tersebut. Dari perhitungan Exposure Scor juga dapat dilihat bahwa nilai untuk punggung dan pergelangan tangan yang berada pada level High yang berarti resiko terjadinya cidera sangat tinggam hal tersebut disebabkan karna kurang nya alat penunjang kerja yang sesuai dengan kebutuhan dari masing-masing operator Untuk itu perlu nya usulan berupa alat penunjang seperti meja kerja dan kursi kerja sehingga diharapkan dapat meminnimalisir resiko cedera otot. Selain itu usulan ini juga dapat meningkatkan kinerja dari para operator. Rancangan perbaikan berupa rancangan fasilitas kerja, yaitu meja kerja operator dan kursi kerja operator dengan menggunakan aplikasi gambar CATIA.
Efektivitas Pemberian Terapi Dingin Terhadap Nyeri Pasien Ortopedi: Literature Review
Authors: Artanti Suci , Haryatmo Sapto
Published: November 2020

Penelitian ini bertujuan untuk mereview keefektifan terapi dingin terhadap nyeri pasien ortopedi, patofisilogi dibalik effektifitas kompres dingin, dan mereview potensial resiko terkait penggunaan terapi dingin. Metode yang digunakan adalah literature review. Literature dicari dengan menggunakan PubMed, Cochrane Library, Google Scholar, dengan kata kunci: “terapi dingin”, “kompres dingin”, “nyeri pasien ortopedi”, “cold terapy”, “cold compress”, “pain of orthopedic patients”. 56 artikel diseleksi dan didapatkan 10 artikel yang relevan. Terapi dingin terbukti efektif menurunkan nyeri pada pasien ortopedi. Terapi dingin merupakan prosedur yang mudah diaplikasikan dan aman bila dilakukan sesuai prosedur. Modifikasi penggunaan alat terapi dingin tidak memberi efek yang signifikan terhadap nyeri akan tetapi meningkatkan kenyamanan pasien. Efek samping penggunaan terapi dingin perlu diteliti lebih lanjut untuk memudahkan penyusunan prosedur yang aman dalam implementasi pemberian terapi dingin pada pasien ortopedi.
Perfil e prática de professores (as) no ensino de sociologia no contexto de sua (des) obrigatoriedade
Authors: Silva Eva
Published: November 2020

Este artigo objetiva apresentar a sistematização do desenvolvimento da pesquisa “O ensino de sociologia nas escolas públicas estaduais de ensino médio de um município do interior de São Paulo”, na qual foi traçado o perfil sociocultural, educacional e profissional de professores (as) de sociologia de escolas do ensino médio. Além disso, foram coletadas, a partir de conversas individuais com os (as) docentes, as representações acerca de suas práticas de ensino dessa disciplina, em suas metodologias e recursos didático-pedagógicos, potencialidades e limites.