bluuebunny/crossref_metadata_2025 huggingface dataset:
Directly observed and reported respectful maternity care received during childbirth in public health facilities, Ibadan Metropolis, Nigeria
Authors: Esan Oluwaseun Taiwo , Maswime Salome , Blaauw Duane
Published: October 2022

Respectful maternity care (RMC) is believed to improve women’s childbirth experience and increase health facility delivery. Unfortunately, few women in low- and middle-income countries experience RMC. Patient surveys and independent observations have been used to evaluate RMC, though seldom together. In this study, we assessed RMC received by women using two methodologies and evaluated the associated factors of RMC received. This was a cross-sectional study conducted in nine public health facilities in Ibadan, a large metropolis in Nigeria. We selected 269 pregnant women by cluster sampling. External clinical observers observed them during childbirth using the 29-item Maternal and Child Health Integrated Program RMC observational checklist. The same women were interviewed postpartum using the 15-item RMC scale for self-reported RMC. We analysed total RMC scores and RMC sub-category scores for each tool. All scores were converted to a percentage of the maximum possible to facilitate comparison. Correlation and agreement between the observed and reported RMC scores were determined using Pearson’s correlation and Bland-Altman analysis respectively. Multiple linear regression was used to identify factors associated with observed RMC. No woman received 100% of the observed RMC items. Self-reported RMC scores were much higher than those observed. The two measures were weakly positively correlated (rho = 0.164, 95%CI: 0.045–0.278, p = 0.007), but had poor agreement. The lowest scoring sub-categories of observed RMC were information and consent (14.0%), then privacy (28.0%). Twenty-eight percent of women (95%CI: 23.0% -33.0%) were observed to be hit during labour and only 8.2% (95%CI: 4.0%-18.0%) received pain relief. Equitable care was the highest sub-category for both observed and reported RMC. Being employed and having completed post-secondary education were significantly associated with higher observed RMC scores. There were also significant facility differences in observed RMC. In conclusion, the women reported higher levels of RMC than were observed indicating that these two methodologies to evaluate RMC give very different results. More consensus and standardisation are required in determining the cut-offs to quantify the proportion of women receiving RMC. The low levels of RMC observed in the study require attention, and it is important to ensure that women are treated equitably, irrespective of personal characteristics or facility context.
Characterization of peptide-protein relationships in protein ambiguity groups via bipartite graphs
Authors: Schork Karin , Turewicz Michael , Uszkoreit Julian , Rahnenführer Jörg , Eisenacher Martin
Published: October 2022

In bottom-up proteomics, proteins are enzymatically digested into peptides before measurement with mass spectrometry. The relationship between proteins and their corresponding peptides can be represented by bipartite graphs. We conduct a comprehensive analysis of bipartite graphs using quantified peptides from measured data sets as well as theoretical peptides from an in silico digestion of the corresponding complete taxonomic protein sequence databases. The aim of this study is to characterize and structure the different types of graphs that occur and to compare them between data sets. We observed a large influence of the accepted minimum peptide length during in silico digestion. When changing from theoretical peptides to measured ones, the graph structures are subject to two opposite effects. On the one hand, the graphs based on measured peptides are on average smaller and less complex compared to graphs using theoretical peptides. On the other hand, the proportion of protein nodes without unique peptides, which are a complicated case for protein inference and quantification, is considerably larger for measured data. Additionally, the proportion of graphs containing at least one protein node without unique peptides rises when going from database to quantitative level. The fraction of shared peptides and proteins without unique peptides as well as the complexity and size of the graphs highly depends on the data set and organism. Large differences between the structures of bipartite peptide-protein graphs have been observed between database and quantitative level as well as between analyzed species. In the analyzed measured data sets, the proportion of protein nodes without unique peptides ranged from 6.4% to 55.0%. This highlights the need for novel methods that can quantify proteins without unique peptides. The knowledge about the structure of the bipartite peptide-protein graphs gained in this study will be useful for the development of such algorithms.
Globalization and employment nexus: Moderating role of human capital
Authors: Mushtaq Mansoor , Ahmed Shabbir , Fahlevi Mochammad , Aljuaid Mohammed , Saniuk Sebastian
Published: October 2022

While globalization has increased the movement and interconnection of goods, technology, and information, it has also affected employment. Many studies have analyzed the impact of globalization on employment creation resulting in positive and negative findings. However, an area of literature still needs to be explored studying how human capital affects the impact of globalization on employment creation. The current study contributes to the literature by analyzing the moderating role of human capital in the globalization-employment nexus in 26 Asian countries. For this, annual panel data were collected from 1996 to 2019. The estimations have been done using 12 model specifications, 6 for direct and 6 for indirect impact association between globalization and employment through the human capital channel. The study uses generalized least square (GLS) method and generalized method of moments (GMM) for empirical analysis. The static and dynamic analysis shows that globalization’s direct and indirect impact on employment through the channel of human capital is positive. Industrial value added and economic growth leads to more employment creation, whereas population growth dampens it. Human capital plays a positive role in getting the advantage of globalization in terms of employment creation. This study confirms the literature recommendations of promoting human capital development to achieve globalization’s benefits for more employment creation.
Body composition reference values in Singaporean adults using dual-energy X-ray absorptiometry—The Yishun study
Authors: Soh BaoLin Pauline , Lee Shuen Yee , Wong Wai Yin , Pang Benedict Wei Jun , Lau Lay Khoon , Jabbar Khalid Abdul , Seah Wei Ting , Chen Kexun Kenneth , Srinivasan Sivasubramanian , Ng Tze Pin , Wee Shiou-Liang
Published: October 2022

Objectives

This study establishes age- and sex-specific reference values for fat mass index (FMI), lean mass index (LMI), appendicular LMI (aLMI), and body fat distribution indices including Android/Gynoid % fat ratio and Trunk/Limb % fat ratio in multi-ethnic Singaporean adults.

Methods

A population-based cross-sectional study using dual-energy X-ray absorptiometry (Hologic Discovery Wi) was carried out to measure whole body and regional fat and lean mass in community-dwelling adults. A total of 537 adults (57.5% women), aged from 21 to 90 years, were recruited from the large north-eastern residential town of Yishun. Age- and sex-specific percentile reference values were generated for FMI, LMI, aLMI, Android/Gynoid % fat ratio and Trunk/Limb % fat ratio using the Lambda–Mu–Sigma method. The relationship between the parameters and age were assessed through the Pearson’s correlation coefficient.

Results

All parameters demonstrated significant correlation with age (p < 0.05) for both men and women, except for LMI in women, with the strength of r ranging from 0.12 (weak correlation) to 0.54 (strong correlation). LMI (r = −0.45) and appendicular LMI (r = −0.54) were negatively associated with age in men while none (r = −0.06) to weak correlation (r = −0.14) were shown in women for the same parameters respectively. The Android/Gynoid % fat ratio and Trunk/Limb % fat ratio were positively related to age for both men (r = 0.37 & 0.43, p < 0.001) and women (r = 0.52 & 0.48, p < 0.001).

Conclusion

We have established DXA-based body composition reference data for the Singapore adult population. These reference data will be particularly useful in geriatric, obesity and oncology clinics, enabling the prescription of appropriate therapy to individuals at risk of morbidity from unfavorable body composition phenotypes. It also adds on to the limited reference database on Southeast Asian body composition.
Role of Scl39a13/ZIP13 in cardiovascular homeostasis
Authors: Hara Takafumi , Yamada Ikuko , Ohashi Takuto , Tamura Masaru , Hijikata Atsushi , Watanabe Takashi , Gao Minghao , Ito Kana , Kawamata Saeko , Azuma Shiori , Yoshigai Emi , Sumiyoshi Yukiko , Yasuhiro Natsumi , Ohara Osamu , Santos Heloísa G. dos , Fukada Toshiyuki
Published: October 2022

Zinc plays a critical role in many physiological processes, and disruption of zinc homeostasis induces various disorders, such as growth retardation, osteopenia, immune deficiency, and inflammation. However, how the imbalance in zinc homeostasis leads to heart disease is not yet fully understood. Cardiovascular diseases are a major cause of death worldwide, and the development of novel therapeutic targets to treat it is urgently needed. We report that a zinc transporter, ZIP13, regulates cardiovascular homeostasis. We found that the expression level of Zip13 mRNA was diminished in both primary neonatal cardiomyocytes and mouse heart tissues treated with the cardiotoxic agent doxycycline. Primary neonatal cardiomyocytes from Zip13 gene-knockout (KO) mice exhibited abnormal irregular arrhythmic beating. RNA-seq analysis identified 606 differentially expressed genes in Zip13-KO mouse-derived primary neonatal cardiomyocytes and Gene ontology (GO) analysis revealed that both inflammation- and cell adhesion-related genes were significantly enriched. In addition, telemetry echocardiography analysis suggested that arrhythmias were likely to occur in Zip13-KO mice, in which elevated levels of the cardiac fibrosis marker Col1a1, vascular inflammation-related gene eNOS, and Golgi-related molecule GM130 were observed. These results indicate the physiological importance of ZIP13—it maintains cardiovascular homeostasis by resolving inflammation and stress response. Our findings suggest that optimizing ZIP13 expression and/or function may improve cardiovascular disease management.
The clinical efficacy and safety of equipment-assisted intravesical instillation of mitomycin C after transurethral resection of bladder tumour in patients with nonmuscular invasive bladder cancer: A meta-analysis
Authors: Zhou Weijian , Liu Jianping , Mao Dongdong , Hu Changying , Gao Dianjun
Published: October 2022

Background

This review and meta-analysis aimed to systematically evaluate the clinical efficacy and safety of equipment-assisted intravesical instillation of mitomycin C (MMC) in patients with nonmuscular invasive bladder cancer (NMIBC) after transurethral resection of bladder tumour (TURBT).

Methods

The Embase, PubMed, CNKI, CBM, WANGFANG, VIP, Cochrane Library, and Clinicaltrial.com databases were searched for articles published before April 2022. The experimental group was treated with intravesical instillation of MMC assisted by equipment, including radiofrequency-induced thermochemotherapy, conductive thermochemical therapy, electromotive drug administration, or locoregional hyperthermia. The control group was treated with simple MMC perfusion. The outcomes of interest in the meta-analysis were recurrence, progression, side-effects, gross haematuria, and bladder irritation.

Results

A total of 15 studies that enrolled 1,190 patients were included in the meta-analysis. Compared to that of the control group, device-assisted intravesical instillation of MMC significantly reduced both tumour recurrence (odds ratio [OR] = 0.32, 95% confidence interval [CI] [0.24, 0.42], P <0.00001) and progression (OR = 0.29, 95% CI [0.12, 0.67], P = 0.004). There were no significant differences between the two groups in terms of safety (OR = 1.21, 95% CI [0.66,2.21], P = 0.54), bladder irritation (OR = 1.06, 95% CI [0.72,1.55], P = 0.78), or gross haematuria (OR = 1.11, 95% CI [0.64,1.94], P = 0.72).

Conclusions

Equipment-assisted intravesical instillation of MMC significantly reduced the recurrence and progression of patients with NMIBC who underwent TURBT and improved their quality of life. Given the significant heterogeneity in research quality and sample size among earlier studies, more prospective, multicentre, large sample randomized controlled trials are needed to supplement and verify this in the future.
Comparative performance of public and private primary care service delivery in Malaysia: An analysis of findings from QUALICOPC
Authors: Ong Su Miin , Lim Ming Tsuey , Fah Tong Seng , Kamaliah M. N. , Groenewegen Peter , Sivasampu Sheamini
Published: October 2022

Introduction

Primary care services are essential in achieving universal health coverage and Malaysia is looking into public-private partnership to overcome resource constraints. The study aims to compare the performance of primary care service delivery dimensions between public and private sector.

Methods

This cross-sectional study used the data from the Malaysian International Quality and Costs of Primary Care (QUALICOPC) study conducted in 2015–2016. The relative performance of each sector in four dimensions was compared using multi-level linear regression by incorporating a dummy variable indicating public sector in the model.

Results

The public sector was shown to have higher performance in comprehensiveness and coordination, while the private sector was better in continuity. There was no significant difference in accessibility. The public primary care services were better in serving primary care sensitive conditions, better informational continuity, and with better skill-mix and inter- and intra- professional relationship. Meanwhile, the private sector was stronger in referral decision making process, specialist feedback and greater out of hours facilities access.

Conclusions

The public and private sectors differ in their strengths, which the government may tap into to strengthen primary care services. Other areas for improvement include seamless care strategies that promote good referral, feedback, and information continuity.
Shared understandings of vaccine hesitancy: How perceived risk and trust in vaccination frame individuals’ vaccine acceptance
Authors: Martinelli Mauro , Veltri Giuseppe Alessandro
Published: October 2022

Extensive research has framed vaccine hesitancy as a property of a heterogeneous group of individuals, ranging from total acceptance to complete refusal. Nevertheless, not much research has explored this heterogeneity, mainly focusing on central tendencies of single belief-related items. Using data from an original survey on a sample of Italian citizens, this paper examines this heterogeneity, exploiting individuals’ cognitive variation to map clusters of individuals who share similar cognitive schemas on vaccine uptake. The results showed the existence three groups, characterized by a different articulation of predictors of vaccine hesitancy, revealing different understandings of vaccine uptake. We then analyzed within-cluster characteristics and showed that cognitive segmentation was connected to different levels of perceived risk, confidence, and support for vaccination. We further showed that cognitive clustering also entailed a mean of social stratification that was correlated with individuals’ educational levels, and that the predictors of vaccine hesitancy were articulated differently in each group. This study, adopting a recent perspective in the analysis of systems of beliefs, moves one step further in disentangling the complexity of vaccine acceptance. Results suggested the usefulness of including individuals’ cognitive characteristics in vaccine hesitancy research and in the development of interventions addressed at increasing vaccine acceptance.
A Novel CNN pooling layer for breast cancer segmentation and classification from thermograms
Authors: A. Mohamed Esraa , Gaber Tarek , Karam Omar , Rashed Essam A.
Published: October 2022

Breast cancer is the second most frequent cancer worldwide, following lung cancer and the fifth leading cause of cancer death and a major cause of cancer death among women. In recent years, convolutional neural networks (CNNs) have been successfully applied for the diagnosis of breast cancer using different imaging modalities. Pooling is a main data processing step in CNN that decreases the feature maps’ dimensionality without losing major patterns. However, the effect of pooling layer was not studied efficiently in literature. In this paper, we propose a novel design for the pooling layer called vector pooling block (VPB) for the CCN algorithm. The proposed VPB consists of two data pathways, which focus on extracting features along horizontal and vertical orientations. The VPB makes the CNNs able to collect both global and local features by including long and narrow pooling kernels, which is different from the traditional pooling layer, that gathers features from a fixed square kernel. Based on the novel VPB, we proposed a new pooling module called AVG-MAX VPB. It can collect informative features by using two types of pooling techniques, maximum and average pooling. The VPB and the AVG-MAX VPB are plugged into the backbone CNNs networks, such as U-Net, AlexNet, ResNet18 and GoogleNet, to show the advantages in segmentation and classification tasks associated with breast cancer diagnosis from thermograms. The proposed pooling layer was evaluated using a benchmark thermogram database (DMR-IR) and its results compared with U-Net results which was used as base results. The U-Net results were as follows: global accuracy = 96.6%, mean accuracy = 96.5%, mean IoU = 92.07%, and mean BF score = 78.34%. The VBP-based results were as follows: global accuracy = 98.3%, mean accuracy = 97.9%, mean IoU = 95.87%, and mean BF score = 88.68% while the AVG-MAX VPB-based results were as follows: global accuracy = 99.2%, mean accuracy = 98.97%, mean IoU = 98.03%, and mean BF score = 94.29%. Other network architectures also demonstrate superior improvement considering the use of VPB and AVG-MAX VPB.
Virological suppression among gay, bisexual, and other men who have sex with men living with HIV in Vancouver, Canada: A longitudinal cohort study from 2012–2017
Authors: Armstrong Heather L. , Gitelman Julian , Cui Zishan , Bacani Nicanor , Sereda Paul , Lachowsky Nathan J. , Card Kiffer G. , Sang Jordan M. , Raymond Henry F. , Montaner Julio , Hall David , Howard Terry , Hull Mark , Hogg Robert S. , Roth Eric A. , Moore David M.
Published: October 2022

Introduction

In 2010, British Columbia (BC) implemented HIV Treatment as Prevention (TasP) as policy. We examined trends in virologic suppression and determinants of significant viremia among a prospective biobehavioural cohort of men who have sex with men (gbMSM) in Vancouver from 2012–2017.

Methods

Respondent-driven sampling was used to recruit sexually active gbMSM (≥16 years) who completed biannual study visits with a computer-assisted self-interview and clinical CD4 and viral load (VL) testing. We linked participant data with the BC HIV Drug Treatment Program to obtain antiretroviral dispensing and VL data. We conducted a trend analysis of VL suppression using univariable generalized estimating equation (GEE) multi-level modelling and multivariable GEE to identify factors associated with episodes of VL ≥200 copies/mL.

Results

Of 774 participants, 223 were living with HIV at baseline and 16 were diagnosed during follow-up (n = 239). We observed a significant trend towards reduced levels of unsuppressed VL (>200 copies/mL) from 22% (07/2012-12/2012) to 12% (07/2016-12/2016) (OR:0.87; 95%CI:0.83–0.91 for each 6-month period). Among those with at least one follow-up visit, (n = 178, median follow-up = 3.2 years, median age = 46.9 years), younger age (aOR:0.97; 95%CI:0.94–0.99, per year), ecstasy use (aOR:1.69; 95%CI:1.13–2.53), crystal methamphetamine use (aOR:1.71; 95%CI:1.18–2.48), seeking sex via websites (aOR:1.46; 95%CI:1.01–2.12), and lower HIV treatment optimism (aOR:0.94; 95%CI:0.90–0.97) were associated with episodes of elevated viremia.

Conclusions

During a period when TasP policy was actively promoted, we observed a significant trend towards reduced levels of unsuppressed VL. Continued efforts should promote HIV treatment optimism and engagement, especially among younger gbMSM and those who use ecstasy and crystal methamphetamine.
How level 5 leadership escalates organizational citizenship behaviour in telecom sector of Pakistan? Exploring mediatory role of organizational dissent
Authors: Sarfraz Rafia , Rathore Kashif , Ali Kashif , Khan Mukaram Ali , Zubair Syed Sohaib
Published: October 2022

Role of leadership in managing organizational behaviour of employees is of key essence. However, at times unconventional behaviour of employees can pose a challenge for the leaders, which in this case is organizational dissent. This study has examined the relationship between level 5 leadership and organizational citizenship behaviour (individual level-OCB-I) in presence of organizational dissent at employing a quantitative approach and a survey design. All managerial cadre employees of telecommunication sector were chosen as a population of the study. Data from 450 respondents from all four telecom companies was analysed using PLS-SEM. The findings of the study revealed that there is direct significant relationship between level 5 leadership and OCB-I of employees i.e., L5L~ OCB-I. Furthermore, the results showed an indirect relationship between level 5 leadership and OCB-I of employees through organizational dissent i.e., L5L~OD~OCB-I is significant. Telecom is a rapidly growing sector that plays a significant role in the economic growth of Pakistan. The study shows that OCB-I in telecom sector of Pakistan can be leveraged through level 5 leadership.
Effects of a farm-specific fecal microbial transplant (FMT) product on clinical outcomes and fecal microbiome composition in preweaned dairy calves
Authors: Slanzon Giovana S. , Ridenhour Benjamin J. , Parrish Lindsay M. , Trombetta Sophie C. , Moore Dale A. , Sischo William M. , McConnel Craig S.
Published: October 2022

Gastrointestinal disease (GI) is the most common illness in pre-weaned dairy calves. Therefore, effective strategies to manipulate the microbiome of dairy calves under commercial dairy operations are of great importance to improve animal health and reduce antimicrobial usage. The objective of this study was to develop a farm-specific FMT product and to investigate its effects on clinical outcomes and fecal microbial composition of dairy calves. The FMT product was derived from feces from healthy donors (5–24 days of age) raised in the same calf ranch facility as the FMT recipients. Healthy and diarrheic calves were randomly enrolled to a control (n = 115) or FMT (n = 112) treatment group (~36 g of processed fecal matter once daily for 3 days). Fecal samples were collected at enrollment and again 9 days later after the first FMT dose. Although the FMT product was rich in organisms typically known for their beneficial probiotic properties, the FMT therapy did not prevent or ameliorate GI disease in dairy calves. In fact, calves that received FMT were less likely to recover from GI disease, and more likely to die due to GI disease complications. Fecal microbial community analysis revealed an increase in the alpha-diversity in FMT calves; however, no major differences across treatment groups were observed in the beta-diversity analysis. Calves that received FMT had higher relative abundance of an uncultured organism of the genus Lactobacillus and Lactobacillus reuteri on day 10. Moreover, FMT calves had lower relative abundance of Clostridium nexile and Bacteroides vulgatus on day 10. Our results indicate the need to have an established protocol when developing FMT products, based on rigorous inclusion and exclusion criteria for the selection of FMT donors free of potential pathogens, no history of disease or antibiotic treatment.
Gait variability during abrupt slow and fast speed transitions in older adults with mild cognitive impairment
Authors: Boripuntakul Sirinun , Kamnardsiri Teerawat , Lord Stephen Ronald , Maiarin Surinthorn , Worakul Puangsoi , Sungkarat Somporn
Published: October 2022

Gait speed modulation, including abruptly decreasing or increasing gait speed, is a challenging task and prerequisite for safe mobility in the community. Older adults with Mild Cognitive Impairment (MCI) exhibit gait deficits under challenging walking conditions which may increase their risk of falls. The purpose of this study was to investigate spatiotemporal variability during slow and fast speed transitions in older adults with and without MCI. Twenty-five older adults with MCI (mean age = 68.56 ± 3.79 years) and 25 cognitively intact controls (mean age = 68.72 ± 4.67 years) participated. Gait performance during gait speed transitions was measured in two walking conditions: 1) a slow to fast speed transition in response to a randomly presented cue, and 2) a fast to slow speed condition in response to a randomly presented cue. Means and variability of spatiotemporal parameters during the transitions were measured and mixed model repeated measures ANOVAs were used to assess interaction and main effects. The older adults with MCI exhibited greater variability of step length (MCI = 13.93 ± 5.38, Control = 11.12 ± 3.15, p = 0.03) and swing time (MCI = 13.35 ± 6.01, Control = 10.43 ± 2.87, p = 0.03) than the controls during the fast to slow speed transitions. No other between-group differences were evident for the gait parameters across the two walking conditions. The findings suggest that older adults with MCI have reduced ability to adapt their gait during transitions from fast to slow walking speeds. This impairment may indicate a decline in automated regular rhythmic gait control and explain in part why this group is at increased risk of falls. Slow speed transition task might be incorporated as a fall risk screening in older adults with MCI.
One year of digital teaching in psychiatry as a response to the COVID-19 pandemic: Knowledge gain and content evaluation of medical students for two summer semesters in 2020 and 2021
Authors: Besse Matthias , Signerski-Krieger Jörg , Wiltfang Jens , Bartels Claudia , Belz Michael
Published: October 2022

After the beginning of the COVID-19 pandemic in 2020, digital teaching had to be implemented by most universities at short notice and widely replaced classroom teaching. As a consequence, digital teaching further reduced direct social interaction for students. One year after the introduction of digital teaching formats at our university medical center (department of psychiatry and psychotherapy), teaching evaluation of students from summer semesters 2020 and 2021 (SS20, SS21) were compared. The main objective of this study was to objectify whether students evaluate digital teaching less favorably after one year of its implementation. Ratings of 311 medical students on (1) knowledge gain, (2) teaching contents and (3) subjective advantages of digital teaching were analyzed for the two separate cohorts SS20 (n = 175) and SS21 (n = 136). Students also rated their pandemic-related stress level, and if learning progress had been reduced by the pandemic in general. Significant knowledge gain was achieved for all included domains in psychiatry (all p < .001), and did not differ between SS20/SS21. Teaching contents in SS21 were rated worse in six out of eight domains compared to SS20 (p < .001 to .05). Also, subjective advantages of digital teaching vanished in most domains comparing the cohorts of SS21 and SS20 (p < .001 to .05). No differences were found for pandemic-related stress level and subjective learning progress. Limitations include the post-hoc design, possible bias from individual exam grades, and sampling bias. The present study showed that knowledge gain can be considered to be stable one year after the pandemic-related implementation of digital teaching. However, sustainability of this teaching format should be monitored critically: The subject of psychiatry and psychotherapy thrives on direct communication, which can be compromised when using digital formats only. In this light, implementation of more interactive formats in digital teaching is discussed.
Psychometric properties of the Slovenian version of Internet Disorder Scale–IDS-15
Authors: Žmavc Mark , Pontes Halley M. , Griffiths Mark D. , Selak Špela
Published: October 2022

Background

Conceptualising internet addiction and assessing its symptoms has presented a significant challenge for researchers over the past 25 years. Recently, the Internet Disorder Scale (IDS-15), which is based on the criteria for Internet Gaming Disorder (IGD) from DSM-5, has emerged as a promising instrument to assess internet addiction. The main objective of the present study was to evaluate the psychometric properties of the Slovenian IDS-15.

Methods

The sample was recruited from the National Survey on the Use of Tobacco, Alcohol and Other Drugs that was conducted in 2018 on a nationally representative sample (N  =  16,000; age range: 15–64 years; 62.4% response rate). The final sample comprised 9,161 participants, with 80.9% reporting having used the internet at least once a week (n  =  7,413). A structured questionnaire was designed and internet addiction was assessed using the IDS-15.

Results

Confirmatory Factor Analysis showed acceptable fit to the proposed four-factor structure of the IDS-15. The reliability, and criterion, convergent and discriminant validity were also found to be adequate with a notable exception of the first item of the scale, as shown by its lower factor loading and higher variability. Additionally, latent profile analysis was used to distinguish between internet users with low (n = 3,818; 51.5%), medium (n = 3,111; 42.0%) and high (n = 484; 6.4%) addiction risk. Furthermore, the high-risk class was associated with higher IDS-15 factor scores, higher frequency of internet use in leisure time, and lower age of first internet use.

Conclusions

The present study provides new insights about the strengths and shortcomings of the IDS-15. Moreover, the results provide an insight into the prevalence of internet addiction in Slovenia, as well as associations with other potential factors. The results serve as the basis for further analyses on internet addiction epidemiology, policymaking activities, and design for targeted public health interventions in Slovenia.
Associations of maximum and reactive strength indicators with force–velocity profiles obtained from squat jump and countermovement jump
Authors: Nishioka Takuya , Okada Junichi
Published: October 2022

Understanding the properties associated with the vertical force–velocity (F–v) profiles is important for maximizing jump performance. The purpose of this study was to evaluate the associations of maximum and reactive strength indicators with the F–v profiles obtained from squat jump (SJ) and countermovement jump (CMJ). On the first day, 20 resistance-trained men underwent measurements for half squat (HSQ) one-repetition maximum (1RM). On the second day, jump performances were measured to calculate the drop jump (DJ) reactive strength index (RSI) and the parameters of F–v profiles (theoretical maximum force [F0], velocity [V0], power [Pmax], and slope of the linear F–v relationship [SFv]) obtained from SJ and CMJ. The DJ RSI was not significantly correlated with any parameter of the vertical F–v profiles, whereas the relative HSQ 1RM was significantly correlated with the SJ F0 (r = 0.508, p = 0.022), CMJ F0 (r = 0.499, p = 0.025), SJ SFv (r = −0.457, p = 0.043), and CMJ Pmax (r = 0.493, p = 0.027). These results suggest that maximum strength is a more important indicator than reactive strength in improving vertical F–v profiles. Furthermore, the importance of maximum strength may vary depending on whether the practitioner wants to maximize the performance of SJ or CMJ.
Lung cancer prediction using machine learning on data from a symptom e-questionnaire for never smokers, formers smokers and current smokers
Authors: Nemlander Elinor , Rosenblad Andreas , Abedi Eliya , Ekman Simon , Hasselström Jan , Eriksson Lars E. , Carlsson Axel C.
Published: October 2022

Purpose

The aim of the present study was to investigate the predictive ability for lung cancer of symptoms reported in an adaptive e-questionnaire, separately for never smokers, former smokers, and current smokers.

Patients and methods

Consecutive patients referred for suspected lung cancer were recruited between September 2014 and November 2015 from the lung clinic at the Karolinska University Hospital, Stockholm, Sweden. A total of 504 patients were later diagnosed with lung cancer (n = 310) or no cancer (n = 194). All participants answered an adaptive e-questionnaire with a maximum of 342 items, covering background variables and symptoms/sensations suspected to be associated with lung cancer. Stochastic gradient boosting, stratified on smoking status, was used to train and test a model for predicting the presence of lung cancer.

Results

Among never smokers, 17 predictors contributed to predicting lung cancer with 82% of the patients being correctly classified, compared with 26 predictors with an accuracy of 77% among current smokers and 36 predictors with an accuracy of 63% among former smokers. Age, sex, and education level were the most important predictors in all models.

Conclusion

Methods or tools to assess the likelihood of lung cancer based on smoking status and to prioritize investigative and treatment measures among all patients seeking care with diffuse symptoms are much needed. Our study presents risk assessment models for patients with different smoking status that may be developed into clinical risk assessment tools that can help clinicians in assessing a patient’s risk of having lung cancer.
CHOP: Maximum Coverage Optimization and Resolve Hole Healing Problem using Sleep and Wake-up Technique for WSN
Authors: Narayan Vipul , Daniel A.K.
Published: October 2022

The Sensor Nodes (SN) play an important role in various hazardous applications environments such as military surveillance, forests, battlefield, etc. The Wireless Sensor Network (WSN) comprised multiple numbers of sensor nodes which are used to perform sensing the physical conditions and subsequently transmitting data to the Base Station (BS). The nodes have limited batteries. The random distribution of nodes in the hazardous areas causes overlapping of nodes and coverage hole issues in the network. The Coverage Optimization and Resolve Hole Healing (CHOP) Protocol is proposed to optimize the network's overlapping and resolve the coverage hole problem. The working phases of the proposed protocol are network initialization, formation of the cluster, Selection of Cluster Head, and sleep and wake-up phase. The issues are optimized, and maximum coverage is achieved for a specific sensing range. Using statistics and probability theory, a link is established between the radius of the node and the coverage area. The protocol used the sleep and wake phase to select optimal nodes active to achieve maximum coverage. The proposed protocol outperformed and showed improvements in the network's performance and lifetime compared to LEACH, TEEN, SEP, and DEEC protocols.
Prevalence and resistance to gastrointestinal parasites in goats: A review
Authors: Mpofu Takalani Judas , Nephawe Khathutshelo Agree , Mtileni Bohani
Published: October 2022

Gastrointestinal parasitism, particularly nematode infection, is a major health issue affecting goats worldwide, resulting in clinical diseases and productivity loss. Prevalent gastrointestinal parasites (GIPs) affecting goats in South Africa are the Strongyloides papillosus, Eimeria spp., and Strongyles, especially the Haemonchus contortus and Trichostrongylus spp. According to the issues discussed in this paper and by other authors, the prevalence and intensity of various GIPs vary with an animal's location, breed, age, sex, and season. Because GIPs easily develop resistance to chemical treatment, selecting and breeding genetically GIP-resistant animals would be a relatively simple and inexpensive strategy for reducing or eliminating the current reliance on chemotherapy. Potential phenotypic indicators for selecting GIP-resistant goats include parasitological, immunological, and pathological phenotypic markers. Synergistic use of these indicators should be encouraged for a more accurate simplified genotype selection of resistant animals. Genes with Mendelian inheritance, particularly those involved in immunoregulatory mechanisms, have been identified in goats. Exploring this knowledge base to develop cost-effective molecular tools that facilitate enhanced genetic improvement programs is a current challenge. Future statistical and biological models should investigate genetic variations within genomic regions and different candidate genes involved in immunoregulatory mechanisms, as well as the identification of single nucleotide polymorphisms known to affect GIP infection levels.
Botsourcing, Roboshoring or Virtual Backoffice? Perspectives on Implementing Robotic Process Automation (RPA) and Artificial Intelligence (AI)
Authors: Kedziora Damian
Published: October 2022

Services, the largest component of the world's economy, have significant impact on shaping economic and social relations between organizations and human beings. For many decades, services sector has been cyclically evolving and changing, which has lately accelerated particularly due to the strong influence of emerging technologies. Certain solutions became a thing of the past, some started to transform faster, while others emerged disturbingly, revolutionizing current state of art. The ways and modes services enable humans and technologies to interact and cocreate value have also started to take new, innovative and fascinating forms. Over the past years, global services market got centralized and technologically reshaped influencing lives of us all. Offshoring (global sourcing), enabled by cloud computing, made multiple transnational companies take advantage of migrating some operational processes to different locations (‘nearshore’ or ‘farshore’).
Representasi Feminisme di Iklan Minuaman Olatte Versi “Taste Of Friendship Ep 1 (Cara Ranty Ungkapin Hati)”
Authors: Paramitha Annisa Widya , Rahardjo Turnomo
Published: October 2022

ABSTRACT

The rapid development of advertising in recent years, since there are many factors, such as: development of modernisation, culture and also internet. Nowadays, advertisement not only find in the television, but you also easily find the advertisement in social media. Youtube is the most used social media, since they have number 1 rank in Indonesia as the favourite of social media, the percentage of the score is 93,8%. This research used semiotics theory by John Fiske to analysis the data. The result of this research finds 3 level from the Olatte’s advertisement, such as: Level of reality, in this level find the4 codes (dress, speech, gesture, makeup and expressions). The second one is level of representation, in this level the researcher find 3 codes (Teknik of camera, lighting and music). The last one in the level of ideology, the researcher finds the liberal of feminism used in this advertisement, also liberal feminism is the most dominant that used in this advertisemet.
THE RELATIONSHIP BETWEEN AWARENESS AND KNOWLEDGE LEVEL OF CLINICAL DENTAL STUDENTS ABOUT ORAL CANCER DISEASE
Authors: Tarius Stefani Marlene , Skripsa Tira Hamdillah , Wulandari Diah Rahayu
Published: October 2022

Background: Oral cancer is the sixth most common type of cancer with two out of three cases occurring in developing countries. As clinical dental students, knowledge and awareness about oral cancer should also be improved with the aim of helping them as future dentists to be more ready to act immediately in prevention phase and early diagnosis of oral cancer.Objective: This study aims to analyze the relationship between the level of knowledge and the level of awareness of dental students about oral cancer.Methods: An observational analytic study with a cross sectional study design. A total of 91 clinical dental students participated in this study. Oral cancer awareness and knowledge level were measured using a pre-validated questionnaire. Spearman’s rho correlation test was used to determine the association between oral cancer awareness and knowledge level of clinical dental students.Results: Out of 91 clinical dental students, 61 (67%) students got excellent-graded awareness and 57 (62,6%) students got good-graded knowledge. Spearman rho correlation test showed oral cancer awareness were significantly associated (p=0,007) with oral cancer knowledge level. Significant positive linear correlations (r=0,279) between oral cancer awareness and knowledge level were also observed from the study results.Conclusion: Clinical dental students’ oral cancer awareness and knowledge level are significantly associated.
SIMULASI LEAN DAN SIKLUS PDCA UNTUK KARTU IDENTITAS ANAK DI DISDUKCAPIL GARUT
Authors: Rahmawati Dewi , Nawangpalupi Catharina Badra
Published: October 2022

Meningkatnya minat masyarakat dalam membuat Kartu Identitas Anak di Kabupaten Garut membuat volume pembuatan menjadi lebih banyak dan berdampak pada lambatnya proses pelayanannya. Hal ini terbukti dimana jumlah pengajuan rata-rata 70 orang per hari menjadi 150 per hari. Berdasarkan hal tersebut, tujuan dari penelitian adalah untuk mengidentifikasi dampak dari lambatnya pelayanan yang berakibat penumpukannya masyarakat di area pelayanan. Adapun metode yang digunakan adalah observasi, wawancara dan melakukan identifikasi pelayanan menggunakan SIPOC dengan cara berfikir  Lean dan siklus PDCA, kemudian dilakukan simulasi menggunakan Arena. Hasil dari penelitian menunjukan bahwa proses pengecekan data yang berulang, kartu tercetak lebih dari satu akibat penginputan data yang ganda atau gagal dalam pencetakan, menunggu verfikasi. Adapun proses pengiriman dokumen dari bagian administrasi ke area pengolahan data merupakan salah satu potensi terjadinya penumpukan dokumen karena lokasinya berbeda. Oleh karena itu, untuk meminimasi hal tersebut dilakukan usulan perbaikan  dan menghasilkan bahwa proses pelayanan KIA dapat dieliminasi dari 5 aktivitas menjadi  menjadi 4  serta petugas pelayanan dari 3 menjadi 2. Pemanfataan petugas menjadi efisien serta melakukan perbaikan layout untuk meminimasi pergerakan dengan memperhatikan proses bekerja dengan menggunakan 5S.
Analisis Program Pengendalian Tuberkulosis dengan Strategi DOTS di Puskesmas Manutapen Kupang
Authors: Mayopu Belinna Eslly , Fretes Fiane De , Tauho Kristiani Desimina
Published: October 2022

Background: Tuberculosis (Tb) is a global challenge for public health problems, including Indonesia. Kupang is the city in East Nusa Tenggara (NTT) that has the highest number of Tb cases with a Success Rate (SR) about 85% in 2017. However, in 2018 the SR rate decreased to about 81%. Adherence to taking medication can have an effect on increasing the SR rate. In NTT, had many cases of withdrawal problems caused by Tb patient not taking medication regularly. The Tb control Program in NTT is based on the Directly Observed Treatment Short Course (DOTS) Strategy that focuses on case finding and cure rates. The five components of DOTS are: 1) Political commitment 2) Case finding 3) Standard treatment 4) Drug management and availability systems 5) Monitoring, recording and reporting system. The purpose of this study is to analyze the implementation of DOTS strategy in Manutapen Public Health Center (Puskesmas)Methods: This study was a descriptive qualitative method with used in-depth interviews. The main informants were three health officer participants from the Puskesmas. Triangulation informants were one participant of the Disease Control and Prevention Program of the Kupang Health Officer, one PMO participant, and one Tb patient participant.Result: Tb control with DOTS strategy encountered obstacles including a lack of political commitment related to funding new Tb cases, the high workload made the Tb officers unable to monitor the patients, and unreported cases.Conclusion: Tuberculosis control program with the DOTS strategy in Manutapen Public Health Center kupang was not optimalized.
Hubungan Kunjungan Antenatal Care (ANC) dengan Kejadian Komplikasi Obstetri di Indonesia : Analisis Data Sekunder Survei Demografi dan Kesehatan Indonesia (SDKI) Tahun 2017
Authors: Sudaryo Mondastri Korib , Sam Aini Qur'ani
Published: October 2022

Background: More than 500,000 mothers died each year due to complications in pregnancy. Even though obstetric complications become unpredictable events and caused more than 90% of maternal deaths at or around delivery. Therefore, the approach taken is to assume all pregnancies are risky. One of the strategies that can be used to prevent and reduce the incidence of maternal mortality in Indonesia is to find out whether there is a relationship between antenatal care (ANC) visit with the incidence of obstetric complications so that further management planning can be done more effectively in terms of lowering maternal mortality in Indonesia. Methods: This study used secondary data from the Indonesia Demographic and Health Survey (IDHS) in 2017 with a cross-sectional design. The sample in this study were mothers aged 15-49 years who had children in the last 5 years who were eligible with the inclusion criteria by taking total sampling.Result: The results of the final modeling of multivariate cox regression analysis showed that there was a relationship between ANC visit with obstetric complications with a PR value of 1.34 (95% CI 1.28-1.41) with a p-value of 0.0001. Conclusion: There is a relationship between ANC visit to obstetric complications in Indonesia after being controlled by parity and place of delivery variables.
ANALISIS EKO-EFISIENSI PADA UKM TEPUNG TAPIOKA (Studi Kasus Pada UD Sinar Cerah Kecamatan Margoyoso Kabupaten Pati)
Authors: Wulan Devi Widyana , Suryoko Sri
Published: October 2022

Eco-efficiency is a concept/strategy the delivery of competitive price of goods and services that satisfy human needs and bring the quality of life, while progressively reducing ecological impacts and resource intensity throughout the life-cycle, to a level at least in line with the earth’s estimated carrying capacity. Eco-efficiency actions include reduction of the material intensity of goods and services, reduction of the energy intensity of goods and services, reduction of toxic dispersion, enhancement of materials recyclability, maximum sustainable, use of renewable resources, extension of product durability, and maximum service intensity of products. The problem that occurs at Tapioca Flour SMEs UD Sinar Cerah is a huge NPO cost which is 78.5% of the total production cost. This study aims to determine the application of eco-efficiency in the Tapioca Flour SMEs UD Sinar Cerah, Margoyoso District, Pati Regency. This research uses a descriptive-analytical method with a qualitative approach. Data collection techniques used include observation, oral interviews ,and literature study. Observations were made on the use of raw materials, water, and energy used in production. The analysis showed that in one year UD Sinar Cerah produced 3,354,780 kg of tapioca flour. The accumulated annual cost of NPO UD Sinar Cerah is Rp. 17,282,564,465.00. UD Sinar Cerah has the opportunity to implement eco-efficiency measures in the process of cutting poles, settling, and encircling to save NPO costs as much as 164,037,436.00 per year. The suggestion given to Tapioca Flour SMEs UD Sinar Cerah is to increase the accuracy and caution in the use of raw materials, energy, and water that has not been measured.