bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH CELEBRITY ENDORSER, BRAND IMAGE DAN BRAND TRUST TERHADAP KEPUTUSAN PEMBELIAN PADA PRODUK EMINA COSMETICS (Survei pada Mahasiswa Fakultas Ekonomi Universitas Slamet Riyadi Surakarta)
Authors: Novalia Ayu , Triastity Rahayu , Triastity Rahayu , Sumaryanto Sumaryanto , Sumaryanto Sumaryanto
Published: October 2022

The purpose of this study was to analyze the significance of the influence of celebrity endorsers, brand image and brand trust on purchasing decisions on Emina Cosmetics products. This type of research is a survey of students of the Faculty of Economics, University of Slamet Riyadi Surakarta. The type of data used is quantitative data and qualitative data. Data sources using primary data sources and secondary data. The population in this study were students who used Emina Cosmetics in the Faculty of Economics at Slamet Riyadi University in Surakarta with a sample of 100 people and the sampling technique used purposive sampling. Data collection techniques using questionnaires, observation and literature study. Data analysis techniques using the instrument test, classical assumption test, descriptive analysis, multiple linear regression analysis, t test, F test, and the coefficient of determination. The results of this study indicate that celebrity endorsers have no significant effect on purchasing decisions, brand image has a significant effect on purchasing decisions and brand trust has a significant effect on purchasing decisions.
Antecedents of E-Loyalty and its Impact to Online Repurchase Intention
Authors: Vallen Putri Utami , Antonio Ferdi
Published: October 2022

Research aims to examined further affect from application design, customer services, fulfillment, responsiveness, compensation, contact, e-service quality, e-WOM, e-recovery on e-loyalty and its impact to online repurchase intention. Data analysis method used PLS-SEM through total of 164 respondents Sayurbox application's users. The finding showed from nine antecedents, likewise from e-loyalty mediating variable, eight variables had significant affect to online repurchase intention and not included contact variable which appears not significant. The strongest affect came from responsiveness and application design. Meanwhile, the direct affect on e-loyalty revealed to be the strongest by e-recovery.
Analysis Of The Influence Of Company Size And Corporate Governance Mechanism On Profit In Consumer Sector Manufacturing Companies Listed On The Indonesia Stock Exchange
Authors: Diandra Soraya  , Puja Rizqy Ramadhan  , Mika Debora Br. Barus
Published: October 2022

The purpose of this research is to provide empirical evidence of the affect of firm’s size, and corporate governance mechanisms on earnings. Firms size was measure by natural logaritma of net sales, and corporate governance mechanisms were measure by three variabels (composition of independent board commisioner, audit quality were measure by industry specialize audit firm, and composition of audit committee). Earnings was measure by net profit. The population of this research is 36 companies in the manufacturing firms focusly consumntion sector which were listed in Indonesian Stock Exchange (IDX). The research data were collected from manufacturing companies’ financial statement for the period of 2018 to 2020. Based on purposive sampling method, there are 16 samples. The reseacrh hypotesis were tested using multiple regression analysis. The results of this research show that firm size and composition of independent board commisioner have positive significant relationships with earnings and then simultaneously firm size and corporate governance mechanism have significant relationship with earning. Variable Auditors’ industry spesialization and composition of audit committee have no significant relationship with earnings.
Implementation of PJOK Learning Media at the Elementary School Level During the COVID-19 Pandemic in Padang Jaya District North Bengkulu
Authors: Perdima Feby Elra , Suwarni  , Dwi Anggara
Published: October 2022

This study aims to determine the application of learning media and the implementation of PJOK learning during the Covid-19 period in Padang Jaya District, North Bengkulu. This type of research is qualitative. The subjects of this study involved 7 PJOK teachers, and 35 elementary school students. Instruments and data collection techniques using observation, questionnaires and interviews. The data analysis technique uses data reduction, data presentation, drawing/conclusion and verification. Based on the results of research on PJOK learning media during the Covid-19 pandemic that used learning media with whatsapp/online and did not get a percentage of 50% of the medium criteria. Based on the results of research from PJOK teachers, 62.32% good criteria and 69, 21% good criteria for students. The results obtained through observation.
Modification of Shooting Kits to Improve Shooting Accuracy in MBO Petanque Students Muhammadiyah Surakarta University
Authors: Barokah Muhammad Hisbul , Nurhidayat
Published: October 2022

This study aims to determine the effect of Modified Shooting Kits on Increase Shooting in MBO Petanque UMS Students. The practice of using modified shooting kits aims to make MBO petanque when running the training program become accustomed to throwing shots on the iron. The method used in this study uses an experimental method and uses a "one group pretest posttest design" design. The test instrument uses the shooting from the FIPJP rules with stations 1,2,3,4,5 and shooting ranging from 6 meters, 7 meters, 8 meters, and 9 meters. students of MBO Petanque UMS who are the subjects of this research. In taking the sample using the purposive sampling technique. Based on the t-test conducted, the data showed that the practice using modified shooting kits had a significant value of 0.003 <0.05 so there was a significant effect of shooting using modified shooting kits accuracy shooting in MBO petanque UMS students. practice model shooting modification kits accuracy shooting of MBO petanque average of pretest average of posttest 17.60 shooting increase of 7.20 for the accuracy of the shooting game compared to before the practice.
Effect of Bench Press Exercise and Triceps Strength Bullet Rejection Ability to be Reviewed from the Flexibility of the Togok to FIK UNM Makassar Students
Authors: Anto Sukamto  , Hikmad Hakim  , Rahma Dewi  , Nurkadri  , Fransen Sinaga
Published: October 2022

Fiction UNM Makassar student. The design used in this study is an experimental method using a 2x2 factorial design. This method is a test (validation) that is testing the effect of one or more variables on other variables. Factorial design is a research design by modifying the post-test-only control or pretest-posttest control group and the researcher adds other variables. The results of the research through hypothesis testing show that Farithmetic between columns (FA) = 26,444, looks bigger than = 4.113, it appears that > or P-value = 0.000 < 0.05 so H0 rejected and H1 accepted. Thus it can be concluded that overall there is a significant difference in the effect between bench press training and triceps strength on O'Brien's shot put ability to FIK UNM Makassar Students. interaction (FAB) = 163.155 and  = 4.113, it appears that > or P-value = 0.000 < 0.05, so H0 rejected and H1 accepted. In other words, it can be stated that the achievement of the O'Brien style shot put ability is influenced by the interaction between the training method and the flexibility of the togok.
Principal Leadership Effectiveness and Some the Determinant Variable
Authors: Basyaruddin Daulay  , Zainuddin  , Nasrun
Published: October 2022

This study aims to answer eight problems related to leadership effectiveness. It is realized that the quality of education in general and the achievement of students in particular is not a stand-alone thing, but it is the result of a learning process that is determined by various factors such as principals, teachers, students, curriculum, source books, libraries, laboratories, and facilities. other supports. The population of this study was the principal of a high school in Medan, amounting to 231 people. Sampling was carried out using a stratified proportional random sampling technique using the Cochran formula to produce a sample of 114 people. The research instrument used a questionnaire with a Likert. Research data is processed and analyzed by path analysis. The results of this study indicate that there is a direct effect of job design on managerial competence 0.5881; job design on achievement motivation 0.3105; job design on leadership effectiveness 0.2481; interpersonal communication on managerial competence 0.1428; interpersonal communication on achievement motivation 0.2573; interpersonal communication on leadership effectiveness 0.1779; teacher managerial competence on leadership effectiveness 0.1644; and achievement motivation on leadership effectiveness 0.1893. It can be stated that increasing the effectiveness of the principal's leadership can be done through job design, interpersonal communication, managerial competence, and achievement motivation.
Development of Athletic Learning Model Based on Traditional Games in Class IV Students Primary School (SD)
Authors: Hari Dirjo Joko Susanto  , Selvi Atesya Kesumawati  , Bayu Hardiyono  , Noviria Sukmawati
Published: October 2022

Athletics is a sport that grows and develops along with natural human activities, running, jumping and throwing are an inseparable part of the long history of Indonesian life. The purpose of this study was to determine the results of the development of a traditional game-based athletic learning model for fourth grade elementary school students. The sample of the small group in this study were students of SD Negeri 87 Palembang, totaling 27 people, while the large group sample was SD Negeri 88 Palembang and SD Negeri 89 Palembang, amounting to 65 people. The stages of the development model carried out are the stages of model analysis, design, development, implementation and evaluation (ADDIE). The instrument used in this research is a questionnaire. The results of the expert validity test using the Content Validity Index (CVI) and Content Validity Ratio (CVR) in the Engklek Question game with an average CVR value of -0.225. Based on these results, it can be said that the development of a traditional game-based athletic learning model for fourth grade elementary school students has good quality as a learning resource.
Analisis pengaruh perputaran modal kerja, struktur modal, dan ukuran perusahaan terhadap profitabilitas
Authors: Richard Ardo Muhamad , Masitoh Endang , Dewi Riana Rachmawati
Published: October 2022

This study looks at how changes in working capital turnover, capital structure, and firm size can affect a profitability. This study covers period from 2016-   2020. The data used in this study annual report for property and real estate sector companies listed on the Indonesia Stock Exchange between 2016 and 2020 period. The population used in this study is all  these companies. In this study, we use multiple linear regression analysis to analyze quantitative data. Sampling method using is objective sampling method Based on the sampling method, there are 13 company in the property and real estate sector that meet the criteria. Financial statement documentation The method used in this study is the method of collecting and recording annual report. The study looked at 65 samples from the company's annual report for 2016-2020. This Study found the working capital turnover and capital structure had an effect on profitability, while company size had no effect. The model determination test showed that the independent variables affected on profitability. This shows that an increase in working capital turnover and capital structure can increase on profitability, and conversely a decrease in working capital turnover and capital structure will reduce on profitability, but this shows that company size does not affect on profitability. Increasing or decreasing company size does not affect profit.
Optimalisasi Wewenang PPNS DJP dalam Penyitaan dan Pemblokiran Aset untuk Pemulihan Kerugian Pendapatan Negara
Authors: Burhan Andi Ulil Amri , Gunadi Gunadi
Published: October 2022

Penegakan hukum pidana di bidang perpajakan khususnya di Indonesia telah memasuki babak baru sejak disahkannya Undang-Undang Harmonisasi Peraturan Perpajakan di Tahun 2021 yang mengedepankan pemulihan kerugian pada pendapatan negara. Pendekatan yang dilakukan dalam pemulihan kerugian pada pendapatan negara dapat melalui keadilan restoratif dan pemulihan aset. Pendekatan keadilan restoratif diwujudkan melalui pengungkapan ketidakbenaran perbuatan sedangkan pendekatan pemulihan aset diwujudkan melalui pembayaran pidana denda. Untuk memastikan pidana denda terbayar, Penyidik Pajak harus memastikan tersedianya aset atau harta milik Wajib Pajak/Penanggung Pajak/Tersangka untuk diamankan dan memenuhi angka kerugian pada pendapatan negara. Wewenang melakukan pemblokiran dan penyitaan terhadap aset yang terkait dan tidak terkait dengan tindak pidana menjadi hal baru yang diatur di dalam ketentuan perpajakan di Indonesia dan diharapkan berujung pada terpulihnya kerugian pada pendapatan negara. Metode yang digunakan peneliti dalam tulisan ini adalah deskriptif kualitatif melalui kajian pustaka dan studi literatur untuk menjelaskan urgensi dari wewenang penyitaan dan pemblokiran aset oleh Penyidik Pajak, menguraikan tantangan yang akan dihadapi, dan rekomendasi untuk optimalisasi pelaksanaan wewenang tersebut. Peneliti menemukan tantangan dari pelaksanaan wewenang tersebut diantaranya disparitas pemahaman aturan dan kegiatan penelusuran aset sedangkan rekomendasi yang dapat peneliti berikan adalah perlunya aturan pelaksanaan dari Undang-Undang Harmonisasi dan Peraturan Perpajakan, sosialisasi pasal pidana kepada penegak hukum lainnya, dan memperkuat kerjasama baik internal maupun eksternal Direktorat Jenderal Pajak. Peneliti menyimpulkan bahwa dengan adanya wewenang ini, maka penegakan hukum pajak di Indonesia dapat mendorong terciptanya efek jera terhadap pelaku tindak pidana di bidang perpajakan dan efek takut terhadap calon pelaku tindak pidana di bidang perpajakan.
Pengaruh Sales Growth, Likuiditas Dan Ukuran Perusahaan Terhadap Financial Distress
Authors: Rochendi Lise Roswati , Nuryaman Nuryaman
Published: October 2022

The company's goal other than making a profit is to be able to continue to grow and survive in the competition, but the emergence of internal threats such as financial difficulties can hinder the achievement of the company's goals. Therefore, management is required to perform optimally in the company's activities, especially financial in order to avoid financial distress. This study aims to determine the effect of sales growth, liquidity and firm size on financial distress. The population of this study are transportation companies listed on the Indonesia Stock Exchange for the 2016-2021 period. The sample selection using purposive sampling technique, the sample obtained is 16 companies with a 6 year observation period so that there are 96 research data. The type of data used in this research is quantitative data. The data collection method uses secondary data in the form of financial reports. The method used is descriptive and verification method using a quantitative approach. The data analysis technique used in this research is logistic regression analysis, coefficient of determination, partial significance test using Eviews version 9. The results show that sales growth has no effect on financial distress, liquidity has no effect on financial distress and the size of the company has a negative effect on financial distress.
Fraud pada Program Jaminan Kesehatan Nasional Perpekstif: Kompetensi Auditor Internal dengan Pendekatan Fenomenologi
Authors: Yusuf Zulfadli , Nurwanah Andi , Sari Ratna
Published: October 2022

Penelitian ini bertujuan menganalisis kompetensi Auditor Internal dengan pendekatan fenomenologi dalam mencegah dan mendeteksi fraud pada program JKN di RSUD Andi Makkasau Parepare. Penelitian ini menggunakan metode kualitatif dengan pendekatan fenomenologi pada Satuan Pengawas Internal di RSUD Andi Makkasau Parepare dengan menggunakan teknik dokumentasi dan wawancara kepada SPI, Verifikator Internal, dan Koder. Peneliti menggunakan rerangka kompetensi inti auditor internal yang disusun oleh The Institute of Internal Auditors (IIA) untuk menganalisis secara deskriptif dengan epoche, reduksi fenomenologi, variasi imajinatif, dan penarikan simpulan terhadap kemampuan mencegah dan mendeteksi fraud program JKN. Hasil penelitian menunjukkan bahwa Auditor Internal SPI RSUD Andi Makkasau Parepare dalam mencegah dan mendeteksi fraud masih belum teruji kualitasnya karena kompetensi yang telah dikuasai belum dimanfaatkan dengan baik. Auditor Internal SPI masih menjalankan program lain dan sebagai Tim Verifikator Insentif Nakes semasa pandemi. Pada praktiknya, indikasi fraud program JKN lebih banyak diungkapkan oleh Verifikator Internal dan Koder. Namun, hal tersebut belum ditindaklanjuti oleh Tim Fraud karena merasa belum pernah menemukan kasus fraud yang menyebabkan terganggunya pelayanan kesehatan.
Analisis Dampak COVID-19 Terhadap Harga Saham Bank Syariah Di Bursa Efek Indonesia
Authors: Suwandi Eko Darmawan
Published: October 2022

This study aims to examine the impact of Covid-19 on the share price of Islamic banks. The research variables used are daily stock price data for Islamic banks for 40 stock trading days before the official announcement of the Covid-19 case in Indonesia and 40 stock trading days after the Covid-19 case was announced. The test results show that there is a difference in the share price of Islamic banks before the announcement of positive cases of Covid-19 in Indonesia and after the announcement of positive cases of Covid-19 in Indonesia, with a significance value of 0.000. After the Covid-19 announcement, it was seen that the share price of Islamic banks fell compared to before the announcement.
Pengaruh Intellectual Capital dan Diversity Gender terhadap Financial Distress Dimoderasi oleh Firm Size
Authors: Ramadanty Amanda Putri , Khomsiyah Khomsiyah
Published: October 2022

The study aimed to investigate the effect of intellectual capital and gender diversity on financial distress as measured by Zmijewski where firm size was as moderating variable. Population involved was that the company properties and real estate listed on the Indonesia Stock Exchange in the period of 2020 until 2021, 130 companies were as the population and the samples were chosen by using purposive sampling. The samples that met the criterion were 100 companies. The hypotheses were investigated by using Moderated Regression Analysis. The results revealed that intellectual capital has a negative effect on financial distress, gender diversity had a positive effect on financial distress. Firm size as moderation strengthens the relationship of intellectual capital and firm size as moderation weakens the relationship gender diversity to financial distress.Companies can pay attention to factors outside the financial statements by increasing intellectual capital in terms of resources, so that the company is able to organize financial performance well so as to avoid financial distress. In addition, the factor of gender diversity as a determinant of the decision making of the board of directors is based on gender. This has an effect on optimal and dynamic decision making. So as to improve the Company's performance and minimize the occurrence of financial distress.
Capital Structure, Accounting Conservatism, Agency Cost, dan Firm Value
Authors: Aprianti Vika , Khomsiyah Khomsiyah
Published: October 2022

The purpose of this research is to evaluate how capital structure, accounting conservatism, and  agency cost impact firm value. The financial reports companies listed on the IDX in 2019–2021 are data utilized in this analysis. The website of the Indonesian Stock Exchange (IDX) supplied the information for this research. There are 671 companies listed in 2019, 716 in 2020, and 769 in 2021. The samples in this research are non-cylicals consumer sector companies. There are 87 companies which was fit the criteria. The study aimed to investigate whether capital structure, accounting conservatism, and agency cost had an effect on firm value. Consequently, there was no effect of the company's capital structure on firm value. This indicates that shareholders are not too focused on capital structure to assess a company. However, companies that had high agency costs followed by good management. Thus, firm value was also high because it could be taken into consideration by shareholders to oversee management actions to support a better firm value. Then, accounting conservatism which showed caution over uncertainty in maintaining the quality of reported earnings. Accounting conservatism has a negative effect on firm value, this indicates that shareholders prefer companies that do not carry out accounting conservatism so that there is no early recognition of losses and company profits remain high.
Pengaruh struktur kepemilikan pada perusahaan keluarga yang terdaftar di Bursa Efek Indonesia: dimoderasi oleh Karakteristik Dewan
Authors: Yopie Santi , Hakim Caroline
Published: October 2022

This study was to examine family ownership, institutional ownership, managerial ownership, and foreign ownership on the performance of family firms. In addition, this study will also examine family ownership which is moderated by the independent board of commissioners and the board of directors. This study uses quantitative methods and is tested using the SPSS application and E-views. The sample in this study is a family company listed on the Indonesia Stock Exchange (IDX) for the period 2017 to 2021. The company's performance variable in this study is measured by Tobin's Q. This study will conduct three tests. The first test is all variables without moderation. The second test is family ownership which is moderated by an independent board of commissioners. The third test is family ownership which is moderated by the board of directors. The results of this study are family ownership and foreign ownership have a significant positive effect on company performance. Meanwhile, institutional ownership, managerial ownership, family ownership moderated by an independent board of commissioners, and family ownership moderated by a board of directors have an insignificant effect on company performance. The results of this study can conclude that not all share ownership can affect the performance of a company.
Pengaruh Produk Domestik Regional Bruto dan Upah Minimum Kabupaten Terhadap Penyerapan Tenaga Kerja Di Kabupaten Bogor Dari Tahun 2010 - 2020
Authors: Rasyid Harun Al , K Agus Tri Indah
Published: October 2022

Penelitian ini bertujuan untuk mengetahui pengaruh produk domestik regional bruto, tingkat upah, terhadap penyerapan tenaga kerja di Kabupaten Bogor  tahun 2010 -2020. Pendekatan yang digunakan adalah pendekatan kuantitatif dengan metode deskriptif. Jenis data dalam penelitian ini adalah data panel berupa sampel dari tahun 2010 - 2020 kabupaten Bogor  dengan penyerapan tenaga kerja tertinggi pada tahun 2019 dengan jumlah 2,791,651 pekerja. Dalam penelitian ini digunakan analisis regresi linear berganda , dengan sistem komputerisasi menggunakan SPSS. Setelah melakukan penelitian dengan data sekunder, dapat disimpulkan ada dua variabel yang mempengaruhi Penyerapan Tenaga Kerja yaitu Produk Domestik Regional Bruto dan Upah Minimum Kabupaten. Hasil penelitian secara simultan atau bersama-sama dalam Uji F, Kedua variable independen yaitu Produk Domestik Regional Bruto dan Upah Minimum Kabupaten secara bersama-sama mempengaruhi Penyerapan Tenaga Kerja di Kota Kabupaten Bogor. Kemudian dengan uji t, Produk Domestik Regional Bruto tidak berpengaruh Positif dan signifikan terhadap Penyerapan Tenaga Kerja di Kabupaten Bogor. Upah Minimum Kota berpengaruh Positif signifikan terhadap Penyerapan Tenaga Kerja di Kota Kabupaten Bogor. maka diperoleh kesimpulan bahwa  upah minimum Kabupaten berpengaruh terhadap Penyerapan tenaga kerja dan secara simultan terdapat pengaruh terhadap variabel bebas yaitu PDRB(X1) dan variabel UMK(X2) terhadap variabel terikat yaitu PTK(Y) dengan nilai adjusted R Square (R2) = 88%, serta 12% sisanya terpengaruh variabel lainnya.
Pengaruh Self Assessment System, Kesadaran Wajib Pajak Dan Account Representative Terhadap Kepatuhan WPOP Yang Melakukan Kegiatan Usaha Dan Pekerjaan Bebas Dengan Preferensi Risiko Sebagai Variabel Moderating
Authors: Fitriasuri Fitriasuri , Ardila Kristina
Published: October 2022

This study aims to determine the effect of the self-assessment system, taxpayer awareness, and account representative on the compliance of individual taxpayers who carry out business activities and independent work. individual taxpayer compliance, the effect of risk preference which acts as a moderating variable of the relationship between taxpayer awareness of individual taxpayer compliance, and the effect of risk preference which acts as a moderating variable of the relationship between account representatives and individual taxpayer compliance. This research was conducted by non-probability sampling method with a sample of 100 respondents from individual taxpayers. The data used are primary data through a questionnaire containing the respondents' answers. The data analysis used in this research is Moderated Regression Analysis. The results of this study show that the self-assessment system has a negative effect, while taxpayer awareness and account representation has a positive effect on individual taxpayer compliance. In addition, the risk preference moderating variable is not able to moderate the effect of the self-assessment system on individual taxpayer compliance, while the risk preference moderating variable can moderate the effect of taxpayer awareness and account representative on individual taxpayer compliance.
Preoperative and Postoperative Factors Affecting Functional Success in Anatomically Successful Retinal Detachment Surgery
Authors: Guner Mehmet Eren , Guner Melis Kabaalioglu , Cebeci Zafer , Kır Nur
Published: October 2022

Purpose: To investigate preoperative and postoperative factors affecting functional success in anatomically successful retinal detachment surgery.Methods: Seventy-five eyes of 75 patients with rhegmatogenous retinal detachment who underwent anatomically successful surgery from 2014 to 2019 with more than 1 year follow-up were included in the study. Demographic characteristics, ocular examination findings, preoperative and postoperative spectral domain optic coherence tomography images were retrospectively evaluated.Results: The mean age was 53.9 ± 17 years (range, 11–85 years). The mean follow-up period was 36.7 ± 16 months (range, 14–72 months). The mean best-corrected visual acuity of the patients before surgery was 1.35 ± 1.24 and at postoperative 12 months was 0.66 ± 0.5 logarithm of the minimum angle of resolution. Patients who were operated in 7 days of visual symptoms onset were found to have better visual acuity at the first and subsequent postoperative exams. Preoperative proliferative vitreoretinopathy, vitreous hemorrhage, and extent of retinal detachment were found to have a negative effect on functional success at 12 months. Regeneration of the outer retinal layers had a positive effect on visual acuity at 12 months but did not significantly increase visual acuity after 12 months. Multivariate analysis showed that preoperative external limiting membrane integrity was significantly associated with better functional outcomes.Conclusions: Early intervention, presence of preoperative external limiting membrane integrity, and restoration of postoperative outer retinal layers positively affected functional success. The presence of preoperative vitreous hemorrhage, preoperative proliferative vitreoretinopathy, and the extent of retinal detachment had a negative effect on prognosis at 12 months.
Fractal Dimension of Peripapillary Vasculature in Primary Open-Angle Glaucoma
Authors: Song Chae Hyun , Kim Seok Hwan , Lee Kyoung Min
Published: October 2022

Purpose: To compare the fractal dimensions of the peripapillary microvasculature as obtained by optical coherence tomography angiography (OCTA) between primary open-angle glaucoma (POAG) and controls.Methods: Optic nerve head and peripapillary area images were taken using the 20° × 20°-scan of Spectralis OCTA (Heidelberg Engineering) in 97 subjects (64 POAG patients, 33 control patients). The optic nerve head microvasculature was evaluated according to predefined slabs: the superficial vascular complex (SVC) and the avascular complex (AVC). The en face image of each slab was processed by ImageJ software (National Institutes of Health) in order to calculate the vessel density and the fractal dimension using the box-counting method. For comparison, the peripapillary retinal nerve fiber layer (RNFL) thickness was obtained from Spectralis OCT circle scans. The utilities of the parameters for discriminating between the POAG and control groups were assessed using areas under the receiver operating characteristic curves (AUCs).Results: The SVC fractal dimension was lower in the POAG than in the control group (p < 0.001), while AVC showed no intergroup difference (p = 0.563). The fractal dimension showed a good correlation with the vessel density in both SVC and AVC (both p < 0.001). In a multivariable regression analysis, the SVC fractal dimension was negatively correlated with age (p < 0.001) and axial length (p < 0.001) and positively correlated with average RNFL thickness (p < 0.001), while the AVC fractal dimension was positively correlated with the Bruch’s membrane opening size (p = 0.013). In terms of diagnostic utility, the AUC was significantly larger for the average RNFL thickness (AUC, 0.889) than for the SVC fractal dimension (AUC, 0.772; p = 0.008).Conclusions: The fractal dimension of SVC was associated with the average RNFL thickness and was reduced in POAG patients. Fractal dimension analysis could be used in evaluating peripapillary vascularity by OCTA.
Ijexá and Music Education: The Study of African-based Music as a Pathway to Valorize Minority Groups’ Collective Identities
Authors: Pereira Adrian Estrela , Konopleva Ekaterina , Dung Do T. , Nyamkhuu Byambasuren , Borodina Daria , Mészáros György
Published: October 2022

In the last decades, the music field has been going through significant changes due to discussions related to colonialism, ownership and representativeness. By questioning traditional music-related values and incorporating debates from diverse social and human sciences, researchers with different backgrounds have become attentive to the function of music education in promoting social justice. Focusing on the Ijexá rhythm, the following article has as its main aim to investigate, analyze and discuss implications of the application of approaches to music education that were developed based on minority groups’ traditional knowledge. Strongly influenced by the critical paradigm’s perspective, this paper presents four specific aims: 1) to present the main sociological, ethnomusicological and religious features of Ijexá; 2) to examine the intentions and effects of traditional Eurocentric approaches to music education; 3) to reflect on the connections between music, music education and collective identities; and 4) to analyze the possible social and educational impacts of the application of decolonization-oriented approaches to music education. Sustained by the aforementioned goals, this research employs the qualitative documental analysis as its methodological approach to examine different sources of written and audiovisual materials, to gather the data, to acquire the information and to develop the knowledge that supports and guides the presented discussions. Its critically oriented reflections intend to contribute to the ongoing scientific debate by investigating the application of an educational approach’s strand that is supported by African-based music and African-based traditions.
Determinants of Intermittent Preventive Malaria Therapy Among Pregnant Women in A Nigerian Teaching Hospital
Authors: O Ogbonna Brian , Amara Ezenne , Nneoma N Okpalanma , I Okeke Anthony , N Maduekwe Hilda , L Okoye Ifunanya , I Ejie Loveth , Amala Ofor , G Osuafor Nkeiruka , N Nnamani Monica , O Maduka Anthony , O Ovwighose Samuel , Ani Njideka Ifeoma , Adaora Ugwu Agatha , Anetoh Maureen , Nnenna Ajagu
Published: October 2022

Background: Intermittent Preventive Treatment of malaria in Pregnancy (IPTp) is mostly issued in most antenatal clinics across the country but there have been reports of poor utilization of this prophylaxis. Objective: This study assessed the determinants of IPTp among pregnant women attending a tertiary hospital in southeast Nigeria. Methods: The study was a descriptive cross-sectional study in which a self-administered questionnaire was distributed to 250 pregnant women receiving antenatal care in the study hospital. The data collected were analyzed with the aid of SPSS, using descriptive and inferential statistics. A p-value of less than 0.05 was considered significant. Results: A majority of the participants responded positively to most of the factors assessed, however, none was statistically significant. Conclusion: Based on these findings, pregnant women at a tertiary hospital in southeast Nigeria are aware of IPTp, nevertheless, most fail to commence the medication at the correct time.
Incidence, Characteristics, Maternal and Perinatal Outcomes of HELLP Syndrome
Authors: KALI Zercan , Cagiran Fatma Tanilir , Kirici Pinar , Meydanli Mehmet Mutlu
Published: October 2022

Objective: HELLP syndrome is associated with increased maternal and fetal complications. It was aimed to provide the incidence of HELLP syndrome and related maternal and neonatal mortality and morbidity. Patients and Methods: Patients diagnosed with HELLP Syndrome within the study period were subsequently assessed in this retrospective study of a 5-years period. Primary outcome was to establish the incidence of HELLP syndrome and to investigate the predicting factors for adverse maternal and fetal outcomes. Secondary outcome was to evaluate the factors related with disseminated intravascular coagulation (DIC). The diagnosis of HELLP syndrome was established with using the Sibai criteria. Results: A total of 12.324 women gave birth during the study period. One hundred four pregnant women were diagnosed with HELLP syndrome with an incidence of 0.84%.The rate of maternal mortality was 2.9% (n=3).Out of all, 86.5% (n=90) of the patients had at least one major complication following the birth. Out of all, 60.6% (n=63) of the neonates had at least one major complication following the birth. The rate of prematurity and IUGR was 61.5% (n=64) and 28.2% (n=29), respectively. There were 3 (2.8%) neonatal deaths. The stillbirth rate was 18.3% (n=19). Conclusion: HELLP syndrome is a serious clinical condition with an incidence of 8.4 per 1,000 deliveries and result in high maternal mortality and morbidity. The lack of a sufficient antenatal follow-up and the rural residence of pregnant women were found to be related with major maternal adverse outcomes.
Nodular and neoplastic skin lesions in an aquarium-managed group of Sabana Surinam toads Pipa parva
Authors: Beck MR , Berliner A , Mangus LM
Published: October 2022

Although skin disease is a common cause of morbidity and mortality in amphibians, published reports of integumentary conditions affecting skin-brooding anurans are extremely limited. This case series describes the clinical, macroscopic, and histopathologic features of nodular skin lesions in an aquarium-managed population of Sabana Surinam toads Pipa parva, a fully aquatic, skin-brooding species native to South America. The skin lesions represented an ongoing clinical concern in this group, affecting approximately 10-20% of animals throughout the study period, and were observed exclusively in females, suggesting an association with the females’ specialized cutaneous reproductive anatomy. Multiple animals died or were euthanized due to skin lesions, which were histologically complex and encompassed a range of hyperplastic, cystic, and neoplastic changes (with internal metastases in one animal). Cultures and special stains showed evidence of mixed polymicrobial infection, including occasional fungal hyphae and acid-fast organisms, but were predominated by Gram-negative bacteria. Lack of a significant response to various environmental modulations and therapeutic interventions indicates that the pathogenesis of the skin lesions is multifactorial. Additional research into the reproductive physiology and ideal environmental conditions (both social and physical) for this species will likely help identify new strategies for prevention and treatment of skin disease.
Qualitative Darwinism
Authors:   , Hofhuis Steije Thomas Hofhuis
Published: October 2022

Why did early modern Europeans hunt for witches? Were witch hunts a shrewd tool to oppress women or the poor, or were they just a way of making money? Or were witch-hunters primarily driven by a genuine belief in witchcraft? The witches’ sabbath, the diabolical pact and the nightly flight were elements in the early modern concept of witchcraft that seem to have been intelligently designed to trigger persistent witch persecutions. But in contrast to many explanations adduced by historians, witch hunts were not based on intelligent design. So how to explain them?

Steije Hofhuis suggests a new theory: Darwinian cultural evolution. He contends that the apparent design underlying the witch hunts emerged from a hidden evolutionary process. That process fostered the preservation of cultural variants which over time accidentally unleashed larger and larger persecutions. Witch-hunts did not so much evolve to serve human interests, but ensured their own “selfish” reproduction.

Historians have often compared witch persecutions to the outbreaks of contagious disease, but only as figure of speech. But shouldn’t we take the similarities more seriously? Were witch-hunts perhaps a cultural ‘virus’ that spread at the expense of its human hosts? This study bridges the gap between qualitative history and the upcoming field of Darwinian cultural evolution. The aim is to contribute to a new research program, based on the qualitative application of Darwinian theory to the humanities
Asthma and Food Allergies
Authors: Foong Ru-Xin , Swan Kate , Fox Adam T
Published: October 2022

There is a close association between various atopic diseases and it is well known that having one atopic disease can increase the risk of further atopy later in life. Research has shown that the development of food allergy in infancy can predispose individuals to the development of respiratory symptoms and subsequent asthma later in childhood. There is also evidence that shows early atopic conditions can be outgrown but may still influence the development of other atopic conditions, such as asthma, in the future. The exact mechanism of how this occurs is not yet fully understood, but the clinical implications for children with both diseases are important because not only are they at greater risk of more severe asthmatic episodes, but also of having respiratory symptoms in food-induced anaphylaxis. This narrative review looks at the relationship between food allergy and asthma and how they are linked to one another. It will also focus on the clinical implications associated with the two atopic conditions and the effect they may have on clinical practice.
Oral Immunotherapy for Food Allergy : What Have We Achieved So Far?
Authors: Anagnostou Katherine
Published: October 2022

The burden of food allergy is significant, multi-faceted, and well documented. In an effort to improve food-allergic patients’ quality of life, there is a continuous effort to provide novel treatment options for food allergy. Food immunotherapy is an exciting area of research that has seen tremendous progress over the last decade. This review examines the current literature and provides insights into key oral immunotherapy studies published so far. Areas requiring further study, the role of food oral immunotherapy, and its potential future applications for patient care are also discussed.
Microbiological Biohazards Associated with Occupational Allergies
Authors: Uzunoglu Emel
Published: October 2022

Microbiological occupational allergens usually originate from a part or products of bacteria, fungi, or arthropods. They may be harmful on their own or their impact may come from cross-reactions of their substance. It is mostly the respiratory system, conjunctiva, and skin that are affected. This short review clarifies the microbiological biohazards associated with occupational allergies.
Pernicious Anaemia: Mechanisms, Diagnosis, and Management
Authors: Ammouri Wafa , Harmouche Hicham , Khibri Hajar , Benkirane Souad , Azlarab Masrar , Mezalek Tazi Zoubida , Maamar Mouna , Adnaoui Mohamed
Published: October 2022

Pernicious anaemia (PA) is an autoimmune disease of multifactorial aetiology involving environmental and immunological factors. It is the most common cause of cobalamin deficiency anaemia worldwide. The disease is a macrocytic anaemia caused by a vitamin B12 deficiency, which, in turn, is the result of intrinsic factor deficiency, a protein that binds avidly to dietary vitamin B12 and promotes its transport to the terminal ileum for absorption. Despite the advances in understanding the pathogenesis and molecular biology, diagnosis of PA is still challenging for clinicians because of its complexity, diverse clinical presentations, and the limitations of the available diagnostic tools for the evaluation of cobalamin status and the presence of chronic autoimmune atrophic gastritis. Asymptomatic autoimmune gastritis, a chronic inﬂammatory disease of the gastric mucosa, precedes the onset of corpus atrophy by 10–20 years. Diagnostic dilemmas could occur when patients with PA present with spuriously normal or high cobalamin levels, normocytic or microcytic anaemia, nonanaemic macrocytosis, autoimmune haemolytic anaemia, pseudo-thrombotic microangiopathy, hyperhomocysteinemia-associated thromboembolism, pseudoleukemia, bone marrow failure, and neurologic manifestations without anaemia or macrocytosis. Other autoimmune disorders, especially thyroid disease, Type 1 diabetes mellitus, and vitiligo, are also commonly associated with PA. The present review focusses on novel aspects regarding the pathogenesis, clinical presentation, and the diagnostic approach of PA; the true usefulness of serum vitamin B12 levels; and the risk of adenocarcinoma and gastric carcinoids as well as their treatment and monitoring strategies.
Recent Findings in the Gut-Liver Axis and Associated Disease Therapy
Authors: Humphry Nicola
Published: October 2022

Several presentations at the recent International Liver Congress™ (ILC), held in London, UK, from 22nd–26th of June 2022, addressed the role of the gut microbiome in chronic liver disease. Debbie L. Shawcross from the Department of Inflammation Biology, School of Immunology and Microbial Sciences, Institute of Liver Studies, King’s College London, UK, outlined the role of the gut-liver axis in the pathogenesis of cirrhosis, and how existing and novel therapies manipulate gut microbes.

Emina Halilbasic from the Medical University of Vienna, Austria, and Benjamin H. Mullish from the Division of Digestive Diseases, Imperial College London, UK. Focused on the use of gut-based therapies in cholestatic liver disease. They explained the current understanding of the interplay between bile acids, microbiota, and the mucosal immune system, and the ways in which this may be manipulated for therapeutic gain.

The role of gut barrier impairment in alcohol-related liver disease (ArLD) was presented by Shilpa Chokshi from the Roger Williams Institute of Hepatology, Foundation for Liver Research, London, UK, and School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King’s College London, UK. Charlotte Skinner from the Department of Metabolism, Digestion, and Reproduction, Division of Digestive Diseases, Imperial College London, UK, described the role of gut proteases in this process, while Jasmohan S. Bajaj from the Virginia Commonwealth University, Richmond, USA, and Central Virginia Veterans Healthcare System, Richmond, USA, illustrated new therapies that target the gut-liver axis in this condition.

Yue Shen from Zhongshan Hospital, Fudan University, Shanghai, China, and the Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, China, described a combined microbiome-metabolome study to characterise the gut microbiome in hepatitis B virus infection-associated liver diseases (HBV-CLD), and how specific microbes might impact peripheral immunity. Finally, Bajaj outlined why the gut is a major target for hepatic encephalopathy (HE) treatment and described cutting edge research into therapies that show promise in this arena, such as soluble solid dispersion rifaximin, faecal microbiota transplantation (FMT), and rationally defined bacterial consortia. Overall, these presentations highlight an expanding knowledge of the gut-liver axis and promise an exciting future in liver treatment.
AKUPRESUR DALAM MENGURANGI EMESIS GRAVIDARUM
Authors: Masdinarsah Imas
Published: October 2022

ABSTRAK

Emesis gravidarum atau morning sikness yaitu keadaan  ibu hamil trimester 1 mengeluh merasa mual  muntah dalam 24 jam terjadi kurang dari 5 kali. Emesis gravidarum adalah rasa mual sera muntah yang dirasakan selama hamil, atau disebut juga dengan morning sickness. Hasil studi  menyatakan  lebih dari 80% wanita hamil  mengalami  emesis gravidarum sepanjang hari. Beberapa penelitian menyatakan emesis gravidarum terjadi pada primigravida 60-80%, pada  multigravida 40-60% (Beatrice knight,2000). Rancangan penelitian ini  quasi eksperimen dengan Pretest Only Design with Control Group. Subjek penelitian dibagi menjadi 2, yakni kelompok perlakuan dan kelompok kontrol. Pada kelompok perlakuan diberikan intervensi berupa akupresur dan pada kelompok kontrol diberikan vitamin B6. Akupresur diberikan kepada ibu  hamil trimester 1 yang mengalami mual muntah selama 30 detik diulang selama 4 kali  (lamanya sampai 2 menit). Sebelum dilakukan akupresur ibu diberikan pemahaman sugesti positif dalam menerima kehamilannya dahulu kemudian dilakukan akupresur. Tindakan akupresur  untuk mengurangi mual muntah dilakukan pada titik P6 dan ST 32. Pada penelitian ini populasinya adalah seluruh ibu hamil Trimester I di Desa Jagabaya  Kecamatan Cimaung  Kabupaten Bandung, Sampel dalam penelitian ini adalah ibu hamil trimester 1 yang mengalami mual muntah . Metode pengumpulan data menggunakan data primer berupa tindakan akupresur pada ibu hamil trimester 1 di titik P6 dan ST 32. Pemantauan dilakukan pada 66 responden yaitu 33 orang responden sebagai kelompok perlakuan dan 33 orang responden sebagai kelompok kontrol dengan melihat keluhan dari ibu hamil  trimester 1 yang mengalami emesis berkurang atau hilang. Analisa data menggunakan uji beda non parametrik (Mann Whitney Test) untuk melihat adanya perbedaan  dari ibu yang mengalami emesis sebelum dilakukan akupresur dan sesudah dilakukan akupresur.