bluuebunny/crossref_metadata_2025 huggingface dataset:
contribuição da sala de recursos na aprendizagem do estudante com deficiência
Authors: Silva Elian Marinho , Aquino Joabson Melo Silva de
Published: February 2024

O artigo apresenta os resultados de pesquisas relacionadas à educação de crianças, adolescentes e jovens com necessidades educacionais especiais, onde foi dada ênfase à busca de uma possível solução para os problemas relativos à atenção à diversidade.  O objetivo do presente trabalho é a modelagem de uma concepção de recursos e suportes para a atenção educacional aos alunos com essas características, mediada pela formação docente. A utilização do método de análise de conteúdo em sua modalidade descritivo-explicativa, modelagem e sistematização de experiências foram os caminhos para a integração de julgamentos, critérios, pontos de vista e avaliações que nortearam a proposta e sua implementação a partir das possibilidades oferecidas pela formação docente. As necessidades educacionais especiais estão relacionadas à deficiência e a estados como alterações comportamentais, dificuldades de aprendizagem generalizadas ou específicas, altas habilidades intelectuais, defasagem educacional e situações sociais diversas; sua complexidade implica um desafio profissional ao qual responde a concepção de desenvolvedor proposta, cuja metodologia fornece soluções alternativas por meio de oficinas de reflexão implementadas com professores em unidades educacionais. Os resultados permitiram concluir que os professores incorporem em sua atuação profissional, elementos teóricos e práticos que favorecessem a atenção aos alunos com necessidades educacionais especiais em condições de inclusão educacional, por meio da reavaliação de recursos e apoio a boas práticas em uma escola inclusiva.
bibliotecário como aliado no combate às fake news no contexto da desinformação
Authors: Ribeiro Ronald de Jesus Alves , Redigolo Franciele Marques
Published: February 2024

A pesquisa aborda o papel do bibliotecário-mediador no combate às fake news e à desinformação. Aborda por meio de conceitos os termos disseminação da informação, letramento informacional e das fake news, a partir de estudos bibliográficos de especialistas na área da Biblioteconomia e Ciência da Informação. O objetivo da pesquisa foi ressaltar a importância desse profissional como mediador da informação no combate das notícias falsas, explicado pela literatura pertinente, onde consiste em identificar o papel do bibliotecário-mediador da informação na responsabilidade social e comprometimento ético com os usuários ao apresentar o letramento informacional nos espaços das bibliotecas como ferramenta de análise crítica da informação. O trabalho é do tipo descritivo e explicativo, de caráter bibliográfico e documental, com abordagem qualitativa. Na análise e discussão dos resultados, o letramento informacional aparece como uma ação que pode ser promovida pelo bibliotecário no combate às fake news e à desinformação. Em suas considerações finais, a pesquisa reforça a importante contribuição do bibliotecário-mediador no combate de notícias falsas, ao promover nos espaços em que atua práticas que envolvam o letramento informacional, seja por meio de palestras, oficinas ou de serviços à comunidade, com fito de minimizar a desinformação na sociedade atual.
Acessibilidade de usuários cegos em bibliotecas universitárias
Authors: Santos Rafael Batista dos , Mota Francisca Rosaline Leite
Published: February 2024

Trabalho em formato de Resumo Expandido.
Sistema Braille como mecanismo para a alfabetização de pessoas com deficiência visual
Authors: Santos Rafael Batista dos , Leite Francisca Rosaline
Published: February 2024

O sistema Braille representa um conjunto complexo de informações que possibilita a comunicação e a educação de pessoas com deficiência visual. Objetivo: discutir sobre o sistema Braille como ferramenta ou instrumento na alfabetização dos deficientes visuais. Metodologia: revisão de literatura, por meio de artigos publicados nas bases de dados SciELO e no Banco Digital de Teses e Dissertações (BDTD). Referencial Teórico: o aprendizado em todas as disciplinas, como matemática, ciências humanas e ciências sociais, está diretamente ligada às habilidades de leitura e escrita e à capacidade de coletar, usar e transmitir informações. Sem dúvida pessoas alfabetizadas podem se destacar na escola e passar para a idade adulta com vantagens competitivas para o emprego e a vida que são menos possíveis para aqueles que não as dominam bem ou não as têm. Considerações Finais: No mundo de hoje, a alfabetização, ou seja, a capacidade de ler e escrever, é vital para o sucesso da educação, de uma carreira e qualidade de vida. Seja focando em um bom livro, discando um número de telefone, fazendo uma lista de compras ou escrevendo um relatório em um computador, ser alfabetizado significa participar efetivamente sociedade. Aprender a ler e escrever em Braille pode fazer uma enorme diferença na vida de uma criança ou adulto com deficiência visual.
Fake news pra quê?
Authors: Cisne Caroline Santos de
Published: February 2024

A pesquisa consiste em apresentar o resultado da aplicação do projeto “Fake News pra quê?” realizado com alunos do 8º ano de uma escola básica municipal da cidade de Biguaçu, estado de Santa Catarina. O projeto, elaborado pela bibliotecária da escola, autora deste artigo, foi implementado em parceria com a professora de português da escola. Neste sentido o artigo demonstra o papel do bibliotecário escolar no enfrentamento às fake news. O projeto aconteceu em 8 (oito) etapas, correspondentes a oito aulas, nas quais a bibliotecária teve participação ativa nas discussões e nos momentos de pesquisa. Finalizado o projeto, foi possível observar o comprometimento e interesse dos alunos pela temática apresentada e ao realizar as atividades propostas. O projeto proporcionou aos alunos o contato com informações falsas e suas consequências, permitiu a leitura e escrita e ainda trabalhou a competência em informação dos alunos.
The Effects of Dairy Consumption on Vaccine Immune Response and Immunoglobulins: A Systematic Literature Review
Authors: Suh Mina , Mitchell Meghan , Hooda Naushin , Bylsma Lauren C. , Cohen Sarah S.
Published: February 2024

Public health interest in vaccinations and immune protection has increased with the COVID-19 pandemic. Dairy products are an important source of protein and other nutrients, and there are unresolved research questions regarding the potential health impact of dairy products on the enhancement of immune response. A systematic literature review was conducted to synthesize the published literature reporting the effects of dairy interventions on: 1) the vaccine-specific immune response and 2) immunoglobulins in the absence of vaccination. To assess study validity and quality, we used the Academy of Nutrition and Dietetics Quality Criteria Checklist. Sixty-one studies (59 clinical trials, 1 cohort, 1 cross-sectional survey) were included, spanning 1983-2017. Ten trials evaluated the effect of dairy intervention on vaccine-specific IgG, IgA, IgM, vaccine-specific antibody titers, seroprotection rates, or seroconversion rates. Of these, 7 reported significant increases with dairy interventions for post-vaccine tetanus antibodies, mean change in tetanus antibody level, total antibody titers to flagellin from Salmonella Adelaide, mean antibody titers to influenza B, influenza-specific IgA and IgG levels, and seroconversion or seroprotection rates for influenza A and B. Fifty-six studies evaluated dairy’s effects on immunoglobulins without vaccinations. The results were heterogenous, with some studies reporting significant enhancement of immunoglobulins (IgA, IgE, or IgG), while others observed no differences between groups. Clinical relevance of the immunoglobulin changes was not investigated in these studies. Dairy products and their components could enhance the efficacy of vaccines. This review highlights the evidence gaps and provides a potential roadmap for additional research.
Use of evidence and expertise in UK climate governance: The case of the Cumbrian Coal Mine
Authors: Willis Rebecca
Published: February 2024

There is a clear scientific consensus that no new coal mines can be developed, if the Paris Agreement to limit global temperature rises is to be met. Yet in December 2022, following a lengthy Public Inquiry, the UK Government approved the development of Woodhouse Colliery in Cumbria. In doing so, it accepted the claim that the coal mine would be ‘zero carbon’, and could even result in lower global emissions overall. As this paper demonstrates, there is no independent evidence to support these claims, whilst a large body of independent evidence comes to the opposite conclusion. This paper uses the example of Woodhouse Colliery to examine the use of evidence and expertise in climate governance processes. It finds that the nature of expertise and evidence is not properly considered, and that there is ambiguity and confusion surrounding the implementation of the UK’s climate legislation, particularly the Climate Change Act. It also finds that the ways in which the decision-making process solicited and assessed evidence was flawed, promoting a ‘false balance’. This ambiguity and false balance provide scope for developers to argue the case for destructive developments, even while claiming adherence to climate ambitions. The paper concludes by suggesting reforms to governance processes, to provide a more transparent and credible implementation of policies to achieve the UK’s net zero target. Suggested reforms include clearer rules governing fossil fuel phase-out; greater transparency and better handling of conflicts of interest in decision-making; and devolution of climate responsibilities to local areas.
Epistemofagia
Authors: Borges Bruno Gonçalves , Fernandes Júnior Antônio
Published: February 2024

Em 1986, Gilles Deleuze publica Foucault. Não parece ser um livro homenagem. Mais do que isso, constitui-se um testemunho da influência ou o registro de um movimento de fluxo e contrafluxo com o pensamento de Michel Foucault na elaboração dos conceitos deleuzianos. Apesar de a referida obra circular no Brasil desde 1988 com tradução local, nos últimos anos ganhou destaque a publicação de Michel Foucault: as formações históricas, tradução dos cursos ministrados por Deleuze que constituem a segunda parte de Foucault. Mas, o que essa nova publicação traz de expectativa? Será ela uma amostra daquilo que todo/a autor/a um dia pode se deparar: (re)dizer o dito, fazer uma (re)leitura sob outras condições (ou até formações)? É nisso que concentrou nosso esforço, pois enxergamos alguns procedimentos que, potencialmente, contribuem para o entendimento do (re)dizer nas suas variadas modulações. Em síntese, esse conjunto procedimental alimentou uma leitura comparada entre os diferentes materiais analisados, de modo que é possível apreender os movimentos operados por Deleuze e como eles exigem uma sensibilidade por parte do leitor e, que, aqui, desdobramos em atos: de escrevinhar e escriturar, e procedimentos: de decupagem e bricolagem da escritura.
O mito da garantia do crescimento a partir de reformas institucionais: a reforma trabalhista brasileira contemporânea (2016-2019)
Authors: Brito Elohá Cabreira , Conceição Octávio Augusto Camargo
Published: February 2024

A visão de que a implantação de um arcabouço institucional adequado é suficiente para a obtenção do crescimento econômico tem prevalecido no terreno acadêmico e político, especialmente no Brasil. Neste contexto, o artigo objetiva: i) analisar, a partir dos estudos de North e Acemoglu, como tal perspectiva decorre de uma interpretação neoclássica da abordagem da Nova Economia Institucional (NEI); ii) resgatar as vertentes heterodoxas da Economia Institucional, para demostrar como essa interpretação neoclássica é um exemplo de mito autorizado; e iii) analisar os reflexos na economia da reforma trabalhista brasileira de 2017, buscando mostrar se a mudança institucional garantiu crescimento econômico.
Os efeitos do Programa Auxílio Emergencial sobre os indicadores da COVID-19: uma análise por Propensity Score Matching
Authors: Caetano de Sousa Junior Valdecy , Rodrigues de Oliveira Raphael , Giomo Danniele
Published: February 2024

O objetivo do artigo é avaliar a eficácia do Programa Auxílio Emergencial (PAE) na redução da probabilidade de os indivíduos apresentarem sintomas relacionados ou testarem positivo para Covid-19. A hipótese testada é que pessoas que receberam Auxílio Emergencial puderam reduzir a circulação e manter um grau mais alto de isolamento social, e por isso tiveram menor propensão a apresentar sintomas relacionados e ou testarem positivo. A metodologia adotada foram os modelos de Pareamento por Escore de Propensão (PSM), com dados da pesquisa PNAD-COVID19 (IBGE) do período de maio a dezembro de 2020. Os resultados encontrados confirmam a hipótese deste trabalho.
Mudanças na persistência da inflação brasileira: uma análise a partir de testes de quebra estrutural
Authors: Herald da Costa Campos Rodolfo , Silva José Alderir da , Geovane Pereira Gomes Thiago , Ferreira da Silva Francisco Danilo , Dos Santos Torres Vagner
Published: February 2024

A persistência da inflação está relacionada com o grau em que os valores futuros de inflação estão relacionados com os choques passados, ou ainda, com a velocidade de ajuste de sua trajetória para o equilíbrio de longo prazo. Este artigo tem como objetivo mensurar a persistência da inflação no período pós Plano Real e verificar possíveis instabilidades neste parâmetro. Modelos univariados e estruturais são utilizados para mensurar a persistência da inflação. Os resultados encontrados sugerem a existência de instabilidades no parâmetro da persistência, com uma diminuição neste valor após a adoção do sistema de metas para a inflação.
Índice da cesta básica e dinâmica de preços dos seus componentes no município de Varginha-MG
Authors: Dos Santos Portugal Júnior Pedro , Augusto Dionísio Vivaldi Guilherme , Franklin Frogeri Rodrigo , Dos Santos Portugal Nilton
Published: February 2024

O presente trabalho examinou o comportamento do Índice da Cesta Básica de Varginha e dos preços dos seus produtos componentes entre junho de 2018 a dezembro de 2021, verificando aqueles que mais influenciaram o desempenho do indicador. Adotou-se a análise quantitativa, com lógica dedutiva e epistemologia positivista. Os resultados mostraram que produtos hortifrutigranjeiros, feijão carioquinha, leite integral e carne bovina juntos explicam 95,5% a variação do Índice da Cesta Básica de Varginha no período estudado. Salienta-se a importância de investimentos na produção local dos produtos alimentícios a fim de minimizar o impacto da volatilidade no valor da cesta básica.
La persistencia del pasado
Authors: Ekerman Maximiliano
Published: February 2024

En el siguiente artículo se reconstruyen las tensiones y conflictos que generó la desarticulación de la censura cinematográfica durante el gobierno de Raúl Alfonsín (1983−1989). Se buscará demostrar que no bastó con la promulgación de una nueva ley de calificación cinematográfica, ni con la creación de un nuevo organismo más plural y democrático para terminar con la influencia que los grupos conservadores habían ejercido sobre el mundo cinematográfico durante décadas. También se busca dar cuenta, de los embates que tuvo que soportar la industria del cine por parte de viejos adversarios como la Iglesia Católica y sus aliados tanto en la justicia como en las ligas católicas, pero también de algunos funcionarios del propio gobierno radical, que buscaron limitar los «excesos de libertad» en la producción de cine. Para desarrollar estas ideas hemos analizado una importante cantidad de fuentes primarias entre las que se destacan principalmente la prensa especializada, el Plan Nacional de Cultura 1984−1989, la legislación cinematográfica, los films cuestionados y una entrevista realizada a Manuel Antín, director del Instituto Nacional de Cine entre los años 1983 y 1989.
«El arte existe por la necesidad humana de plasmar nuestra experiencia viva»
Authors: Solá Paola
Published: February 2024

Escritora, cineasta y guionista, Paula Markovitch nace el 28 de mayo de 1968 en la ciudad de Buenos Aires. Hija de los artistas Genoveva Edelstein y Armando Markovitch -insiliados en San Clemente del Tuyú durante la última dictadura militar- creció en una pequeña y modesta casa frente al mar rodeada del arte de sus padres. Con una inclinación temprana hacia las letras, escribe desde los ocho años y aún hoy recuerda con cariño y admiración sus primeras obras escritas en un taller de dramaturgia dictado por Griselda Gambaro. En la ciudad de Córdoba, conoce al guionista y cineasta Sergio Schmuler, quien le propone mudarse a México para poder trabajar y vivir de la escritura -entre otros textos- de guiones cinematográficos. Allí, lleva dirigidas cuatro películas. 

Sus películas están atravesadas por una mirada sobre el arte como una necesidad vital transformadora tanto para el artista como para el mundo, en las que busca trasmitir lo que llama una experiencia viva.
Percepción de la prensa sobre la tuberculosis en Barranquilla (Colombia) 1938 - 1946
Authors: Bilbao Ramírez Jorge Luis , Acuña Reyes Estefany Paola , Martínez Sequeira Mayte , Pertuz Yepes Katia , Vidal Martínez Jecenia , Crespo Camacho Elvira
Published: February 2024

El objetivo de esta investigación fue comprender la percepción de la prensa en torno a la tuberculosis como enfermedad y el paciente tuberculoso de la Ciudad de Barranquilla (Atlántico, Colombia), durante el periodo comprendido entre 1938 ?Creación del Ministerio de Trabajo, Higiene y Previsión Social? y 1946 ?Creación del Ministerio de Higiene?, a partir de un análisis documental del diario “La Prensa”. Las categorías emergentes comprendieron la percepción de la enfermedad, paciente tuberculoso, prevención, tratamiento antituberculoso e institucionalización. El análisis mostró que el diario “La Prensa” orientaba su percepción a considerar al paciente tuberculoso como pobre, residente en viviendas no higiénicas y con mala higiene privada, evidenciándose una exculpación del Estado e invisibilidad de probables casos de la enfermedad en personas de la élite. Asumiendo además el rol de divulgador de noticias emanadas de instituciones, funcionarios públicos y representantes de organizaciones sociales que defendían su actuar en la Lucha Antituberculosa.
Antimicrobial peptides and other potential biomarkers of critical illness in SARS‐CoV‐2 patients with acute kidney injury. AMPAKI‐CoV study
Authors: Theotonio dos Santos Lucas Ferreira , Barbeiro Hermes Vieira , Barbeiro Denise Frediani , de Souza Heraldo Possolo , Pinheiro da Silva Fabiano
Published: February 2024

Antimicrobial peptides (AMPs) constitute a complex network of 10–100 amino acid sequence molecules widely distributed in nature. While over 300 AMPs have been described in mammals, cathelicidins and defensins remain the most extensively studied. Some publications have explored the role of AMPs in COVID‐19, but these findings are preliminary, and in vivo studies are still lacking. In this study, we report the plasma levels of five AMPs (LL‐37, α‐defensin 1, α‐defensin 3, β‐defensin 1, and β‐defensin 3), using the ELISA technique (MyBioSource, San Diego, CA, United States, kits MBS2601339 (beta‐defensin 1), MBS2602513 (beta‐defensin 3), MBS703879 (alpha‐defensin 1), MBS706289 (alpha‐defensin 3), MBS7234921 (LL37)), and the measurement of six cytokines (tumor necrosis factor‐α, interleukin‐1β, interleukin‐6, interleukin‐10, interferon‐γ, and monocyte chemoattractant protein‐1), through the magnetic bead immunoassay Milliplex® and the MAGPIX® System (MilliporeSigma, Darmstadt, Germany, kit HCYTOMAG‐60 K (cytokines)), in 15 healthy volunteers, 36 COVID‐19 patients without Acute Kidney Injury (AKI) and 17 COVID‐19 patients with AKI. We found increased levels of α‐defensin 1, α‐defensin 3 and β‐defensin 3, in our COVID‐19 population, when compared to healthy controls, along with higher levels of interleukin‐6, interleukin‐10, interferon‐γ, and monocyte chemoattractant protein‐1. These findings suggest that these AMPs and cytokines may play a crucial role in the systemic inflammatory response and tissue damage characterizing severe COVID‐19. The levels of α‐defensin 1 and α‐defensin 3 were significantly higher in COVID‐19 AKI group in comparison to the non‐AKI group. Furthermore, IL‐10 and the product IL‐10 × IL‐1B showed excellent performance in discriminating AKI, with AUCs of 0.86 and 0.88, respectively. Among patients with COVID‐19, AMPs may play a key role in the inflammation process and disease progression. Additionally, α‐defensin 1 and α‐defensin 3 may mediate the AKI process in these patients, representing an opportunity for further research and potential therapeutic alternatives in the future.
25 Jahre Fachangestellte für Medien- und Informationsdienste: Ein kurzer Rück- und Ausblick
Authors: Holste-Flinspach Karin
Published: February 2024

1998 bis 2023: Aus Anlass von 25 Jahren FaMI-Ausbildung ein Rückblick auf die Entstehungsgeschichte des Berufes, seine Entwicklung und ein Ausblick auf die derzeitige von Neuordnungsbestrebungen bestimmte Entwicklung.
„Steter Tropfen höhlt den Stein“ – es braucht einen langen Atem auf dem Weg zur Barrierefreiheit
Authors: Büchel Claudia
Published: February 2024

Es dauerte insgesamt zehn Jahre, bis die Stadtbibliothek Neuss (Rhein-Kreis Neuss, NRW) die Kriterien erfüllte für das Signet „Neuss barrierefrei“. Sie verfolgt dabei einen ganzheitlichen Ansatz, der Vermittlungs- und Medienangebote, Veranstaltungen, Fortbildungen für die Mitarbeitenden und eine kompetente Ansprechpartnerin umfasst.
Effectiveness and safety of a mumps containing vaccine in preventing laboratory-confirmed mumps cases from 2002 to 2017: A meta-analysis
Authors: Gao Bu-Gang , Huang Ling-feng , Xie Ping
Published: February 2024

Emerging evidence has figured that serum conversion rate of mumps is a crucial link of mumps disease. Nevertheless, a rising number of mumps outbreaks caused our attention and studies examining the serum conversion cases were conducted in small samples previously; this meta-analysis was conducted to assess the immunogenicity and safety of a mumps containing vaccine (MuCV) before 2019. We identified a total of 17 studies from the year of 2002–2017. In the case–control studies, the vaccine effectiveness (VE) of MuCV in preventing laboratory-confirmed mumps was 68% (odds risk: 0.32; 95% confidence interval [CI], 0.14−0.70) while in the cohort studies and randomised control trials, 58% (relative risk [RR]: 0.42; 95% CI, 0.26−0.69). Similar intervals of effectiveness rates were found during non-outbreak periods compared with outbreak periods (VE: 66%; RR: 0.34; 95% CI, 0.18−0.68 versus VE: 49%; RR: 0.51; 95% CI, 0.21−1.27). In addition, the MuCV group with two and three doses did not show enhanced laboratory-confirmed mumps than one dose (VE: 58%; RR: 0.42; 95% CI, 0.20−0.88 versus VE: 65%, RR: 0.35; 95% CI, 0.20−0.61) for the reason of the overlap of 95% CI. MuCV had comparable effectiveness comparing non-outbreak and outbreak period, one dose, and two or three doses. MuCV displayed acceptable adverse event profiles.
Issues in assessing analytical performance specifications in healthcare systems assembling multiple laboratories and measuring systems
Authors: Theodorsson Elvar
Published: February 2024

Analytical performance specifications (APS) are usually compared to the intermediate reproducibility uncertainty of measuring a particular measurand using a single in vitro diagnostic medical device (IVD MD). Healthcare systems assembling multiple laboratories that include several IVD MDs and cater to patients suffering from long-term disease conditions mean that samples from a patient are analyzed using a few IVD MDs, sometimes from different manufacturers, but rarely all IVD MDs in the healthcare system. The reproducibility uncertainty for results of a measurand measured within a healthcare system and the components of this measurement uncertainty is useful in strategies to minimize bias and overall measurement uncertainty within the healthcare system. The root mean squares deviation (RMSD) calculated as the sample standard deviation (SD) and relative SD includes both imprecision and bias and is appropriate for expressing such uncertainties. Results from commutable stabilized internal and external control samples, from measuring split natural patient samples or using big-data techniques, are essential in monitoring bias and measurement uncertainties in healthcare systems. Variance component analysis (VCA) can be employed to quantify the relative contributions of the most influential factors causing measurement uncertainty. Such results represent invaluable information for minimizing measurement uncertainty in the interest of the healthcare systemʼs patients.
Lessons in clinical reasoning – pitfalls, myths, and pearls: a woman brought to a halt
Authors: Rezigh Austin , Rezigh Alec , Sherman Stephanie
Published: February 2024

Objectives

Limitations in human cognition commonly result in clinical reasoning failures that can lead to diagnostic errors. A metacognitive structured reflection on what clinical findings fit and/or do not fit with a diagnosis, as well as how discordance of data can help advance the reasoning process, may reduce such errors.

Case presentation

A 60-year-old woman with Hashimoto thyroiditis, diabetes, and generalized anxiety disorder presented with diffuse arthralgias and myalgias. She had been evaluated by physicians of various specialties and undergone multiple modalities of imaging, as well as a electromyography/nerve conduction study (EMG/NCS), leading to diagnoses of fibromyalgia, osteoarthritis, and lumbosacral plexopathy. Despite treatment for these conditions, she experienced persistent functional decline. The only definitive alleviation of her symptoms identified was in the few days following intra-articular steroid injections for osteoarthritis. On presentation to our institution, she appeared fit with a normal BMI. She was a long-time athlete and had been training consistently until her symptoms began. Prediabetes had been diagnosed the year prior and her A1c progressed despite lifestyle modifications and 10 pounds of intentional weight loss. She reported fatigue, intermittent nausea without emesis, and reduced appetite. Examination revealed intact strength and range of motion in both the shoulders and hips, though testing elicited pain. She had symmetric hyperreflexia as well as a slowed, rigid gait. Autoantibody testing revealed strongly positive serum GAD-65 antibodies which were confirmed in the CSF. A diagnosis of stiff-person syndrome was made. She had an incomplete response to first-line therapy with high-dose benzodiazepines. IVIg was initiated with excellent response and symptom resolution.

Conclusions

Through integrated commentary on the diagnostic reasoning process from clinical reasoning experts, this case underscores the importance of frequent assessment of fit along with explicit explanation of dissonant features in order to avoid misdiagnosis and halt diagnostic inertia. A fishbone diagram is provided to visually demonstrate the major factors that contributed to the diagnostic error. The case discussant demonstrates the power of iterative reasoning, case progression without commitment to a single diagnosis, and the dangers of both explicit and implicit bias. Finally, this case provides clinical teaching points in addition to a pitfall, myth, and pearl specific to overcoming diagnostic inertia.
Static behavior of piled raft foundation in clay
Authors: Alnumairi Zainab Sadoon , AlShareefi Suhair Razzaq
Published: February 2024

Wall piles supported with anchors are considered one of the most prevalent types of engineering support. This research includes studying the behavior of wall piles through a numerical parametric study using the FE-method program (PLAXIS 2D). The study includes the most influencing factors such as the angle of the inclination, the vertical spacing between the rows of anchors, and the distance of the first row of anchors from the ground surface. The effects of these factors on the stability of the wall were studied. Optimal positioning of the anchors is crucial, as it maximizes their effectiveness and contributes significantly to reducing the overall construction costs. The use of a guys queue for the economic aspect saves the cost of executing two guys queue because the effect of having two rows does not significantly change the transfer values. The optimum angle of inclination of the tensioner row is 15° in favor of safety, and as it gives good stability of the wall to the wedge wall, with an increase in this angle, the horizontal movement decreases. The first optimum dimension for a row of guys from the horizontal surface of the earth is O = 25%H. Decrease the values of horizontal movement of the wall by increasing the angle of friction.
Removal of phytic acid in protein via pretreatment of rapeseed meal
Authors: Li Yanlei , Sun Yiying , Lu Lin , Gao Zhiming , Wu Yuehan , Yuan Dan , Jiang Wenxin
Published: February 2024

To obtain rapeseed protein with low phytic acid (PA), soy protein isolate (SPI) was used to investigate the interactions between SPI and PA. The influence of pretreatment (soaking using salt solution and dialysis) of the defatted rapeseed meal on the PA and protein content in the final rapeseed proteins was also studied. The results showed that electrostatic interactions dominated the protein–PA interaction, which was affected by pH and ionic strength. Accordingly, the pH and ionic strength in the soaking medium also influenced the PA remained in the rapeseed proteins. The PA content decreased with the ionic strength (400–800 mM) and relatively low PA was obtained at pH 6.0 (soaking environment). Finally, 52.8 % of the PA have been removed and PA content remained in rapeseed protein isolate (RPI) reached about 0.84 mg/g, at the same time, the protein content was maintained around 86.70 %. Overall, soaking using salt solution and dialysis could be an effective method to achieve high quality rapeseed protein with low PA.
Realizing finite groups as automizers
Authors: Bayard Sylvia , Lynd Justin
Published: February 2024

It is shown that any finite group 𝐴 is realizable as the automizer in a finite perfect group 𝐺 of an abelian subgroup whose conjugates generate 𝐺.
The construction uses techniques from fusion systems on arbitrary finite groups, most notably certain realization results for fusion systems of the type studied originally by Park.
Predicting cued and oddball visual search performance from fMRI, MEG, and DNN neural representational similarity
Authors: Yeh (葉律君) Lu-Chun , Thorat Sushrut , Peelen Marius V.
Published: February 2024

Capacity limitations in visual tasks can be observed when the number of task-related objects increases. An influential idea is that such capacity limitations are determined by competition at the neural level: two objects that are encoded by shared neural populations interfere more in behavior (e.g., visual search) than two objects encoded by separate neural populations. However, the neural representational similarity of objects varies across brain regions and across time, raising the question of where and when competition determines task performance. Furthermore, it is unclear whether the association between neural representational similarity and task performance is common or unique across tasks. Here, we used neural representational similarity derived from fMRI, MEG, and deep neural networks (DNN) to predict performance on two visual search tasks involving the same objects and requiring the same responses but differing in instructions: cued visual search and oddball visual search. Separate groups of human participants (both sexes) viewed the individual objects in neuroimaging experiments to establish the neural representational similarity between those objects. Results showed that performance on both search tasks could be predicted by neural representational similarity throughout the visual system (fMRI), from 80 msec after onset (MEG), and in all DNN layers. Stepwise regression analysis, however, revealed task-specific associations, with unique variability in oddball search performance predicted by early/posterior neural similarity, and unique variability in cued search task performance predicted by late/anterior neural similarity. These results reveal that capacity limitations in superficially similar visual search tasks may reflect competition at different stages of visual processing.

Significance StatementVisual search for target objects is slowed down by the presence of distractors, but not all distractors are equally distracting – the more similar a distractor is to the target, the more it slows down search. Here, we used fMRI, MEG, and a deep neural network to reveal where, when, and how neural similarity between targets and distractors predicts visual search performance across two search tasks: oddball visual search (locating the different-looking object) and cued visual search (locating the cued object). Results also revealed brain regions, time points, and feature levels that predicted task-unique performance. These results provide a neural basis for similarity theories of visual search and show that this neural basis differs across visual search tasks.
Informing Policy and Responding to Crisis
Authors: Hein HannaLore
Published: February 2024

This article explores historians’ role in shaping public policy amid crises through the programs of the Idaho State Historical Society (ISHS). ISHS navigated the post-2008 recession, aligning with the History Relevance Campaign to redefine history’s societal value and develop a legislative outreach program. This article encapsulates the ISHS’s journey and history’s power—through the agency’s new briefing paper program—to inform, unite, guide policy, and promote informed governance. The article describes the author’s workflow, which features traditional research methodology and adaptable project management philosophies and stresses the value of searchable research libraries as a framework for historians to manage multiple projects.
Commemorating in Place
Authors: Auerbach Joanna
Published: February 2024

What makes historical tourism so compelling? The author reflects upon her personal experience of Holocaust tourism to tease out its meaning and appeal. The paper considers the making of meaning through the in-situ experience, including through association, sensory perception, and imagination. The paradigm of dark tourism, traditionally associated with superficial consumption, is dismissed as being too naive a rendering of the visitor experience. Instead, the author commends the tourist’s inherent capacity to make connections between the past and the present, and thereby generate meaning. Ultimately, however, the author finds her most authentic response to “being there” is one of commemoration, since she knows that what she is visiting in the present is not history itself, but merely a memory of it.
The Rhetoric of Freedom
Authors: Hollis Sylvea
Published: February 2024

Over the past few years, the National Council on Public History (NCPH)’s annual meeting has given attention to the forthcoming 250th anniversary of the American Revolution. NCPH has worked with the National Park Service (NPS) to present a scholar’s roundtable with different annual themes. The roundtable at the 2023 meeting examined “The Rhetoric of Freedom.” This essay opens with an exploration of the theme. What follows is an introduction to the scholars who participated in the roundtable; a description of their suite of programming; and a summary of their findings. I close with a “best practices” case study of the Aiken-Rhett House, an urban plantation mansion in Charleston, South Carolina. The case study answers a reoccurring question that emerged from roundtable discussions: How do historians engage public(s) in narratives of freedom, bondage, and nation building?
The first pain and palliative care unit in mozambique: howit all began?
Authors: Pinto Emilia , Schwalbach Teresa , Gonçalves Ferraz , Sacarlal Jahit , Castro Luisa , Rego Guilhermina
Published: February 2024

Background: Access to health care is a major challenge in low- and middle-income countries. Dispite its limitation in Africa, countries such as Uganda, South Africa and Kenya top the list with the largest number of specialist hospices. Although there are Palliative Care (PC) Policies in Mozambique since 2012 which are approved by the Ministry of Health that provide for the integration of this care at all levels. However, there was no integration into the National Health System, until 2017. One of the necessary measures for the development of PC in a country is the integration of PC into the structure and financing of the National Health System. The process of implementing PC in Mozambique begun in 2009 with the creation of the Mozambican Palliative Care´s Association, PC Policies, the Curriculum Design and PC Reference Manual in 2012, and the Mozambican Pain Study Association in 2013. In response to the progressive increase in HIV/AIDS patients, and particularly those with cancer with palliative needs and suffering. In the main hospital of the country, in the Pain Unit, Palliative Care Service was oppened in September 2019 resulting in the Pain and Palliative Care Unit. It has multidisciplinary specialized professionals team, the first in Portuguese-speaking African countries. However, the similarity to many other countries with few resources, access and availability of opioids was a harsh reality. Conclusion: Mozambique was the first Portuguese-speaking African Country to create a Pain and Palliative Care Unit with a specialized team. However, access and availability of opioid drugs is one of the major challenges.
Epidemiological data on lower limb lymphedema
Authors: Pereira de Godoy Jose Maria , Pereira de Godoy Capeletto Paula , Carolina Pereira de Godoy Ana , Maria Pereira de Godoy Lívia , Jose Pereira de Godoy Henrique
Published: February 2024

Objective: The aim of the present study was to evaluate epidemiological data of patients seen at a clinic specialized in the treatment of lymphedema. Methods: A retrospective, cross-sectional study was conducted involving data from 150 consecutive patients with lower limb lymphedema in clinical stages II and III treated at the Godoy Clinic in São Jose do Rio Preto. The follow data were collected: sex, age, type of lymphedema (primary or secondary), cause of secondary lymphedema (cancer, trauma, venous disease) and limb dominance. The diagnosis of lymphedema was based on the clinical history and physical examination; in cases of doubt, lymphoscintigraphy of the lower limbs was requested. Descriptive statistics were performed and results were expressed as percentages. Results: Twenty-five (16.66%) of the patients were male and 125 (83.33%) were female. Mean age was 42.52 years (41.8 years among the men and 42.67 years among the women). One hundred nine cases (72.66%) were primary lymphedema and 41 (27.33%) were secondary. Among the secondary cases, 27 (18%) were related to cancer treatment, 10 (6.6%) were linked to trauma and four (2.6%) were cases of phlebolymphedema. Mean age was 51.4 years among the patients with cancer treatment-related lymphedema, 41 years among those with trauma-related lymphedema and 64.25 years among those with phlebolymphedema. The left leg was affected in 61 cases (40.66%), the right leg was affected in 37 cases (24.66%) and lymphedema was bilateral in 52 cases (34.66%). Conclusion: Primary lymphedema was predominant and affected women more than men. Primary lymphedema occurred at an earlier age compared to cancer treatment-related lymphedema and phlebolymphedema. The left leg was affected more often, followed by bilateral lymphedema and, finally, the right leg alone.
Mathematical biology: a powerful science for progress
Authors: Kllogjeri Qamil , Kllogjer Pellumb
Published: February 2024

This paper is about mathematical biology as a new fast growing and cooperative field of the two sciences: biology and mathematics. The challenge is that more quantitative becomes the biology science, wider and deeper becomes the application of mathematics in this science, hence more exciting results will be in the global scope. Many experiments in biology need quantification in order to make measurements, to discover and estimate the influence of different factors in the phenomenon under study, and draw right conclusions. An example is the estimation of the total number of choices a fly faces while travelling through the apparatus for fractionating the flies. The combinations of the successive choices result with a great number. Comparative experiments estimate differences in response between treatments or between the two groups involved in the experiment. There are many cases where the comparisons are biased, no matter how precise the measurements are done, because of the way a group is partitioned into two subgroups. The biologist needs to know all the possible partitions and the respective numbers of comparisons, make them part of the experiment and find out which partition gives the lowest error. In this paper our intention is to help biologists and researchers with few formulas that can be used for calculations in different experiments.
Evaluation of two biostimulants in soybean production
Authors: Jorge Suárez Héctor , Zuaznabar Zuaznabar Rafael , González Nuñez Miguel González Nuñez , Rosa González Juan Carlos , González Rodríguez Juan Miguel
Published: February 2024

The results of a study of soybean (Glycine max, (L.)) are presented, which was developed in areas of the Basic Sugarcane Seed Bank of the province of Cienfuegos, located in areas of the Espartaco community with the variety INIFAT- 70. The study was planted on May 24 and harvested on September 12 with 111 days, the application of biostimulants was carried out on July 19 at 55 days after planting, the randomized block design was used with 3 treatments (Control, FitomasEC and Fitomasplus) and 5 replicates, in plots of 36 m2. The seed used was basic from the bank itself with more than 95% germination and the study area was not fertilized. The treatments used were: Witness and/or control, FitomasEC an application at 2 liters ha-1, Fitomasplus an application 2.0052 liters ha-1 (tank mix 2 liters ha-1 of FitomasEC and 5.2 milliliters ha-1 of enerplant), The variables evaluated were ton ha-1 and the economic valuation. A simple classification analysis of variance (ANOVA) was performed and as there were significant differences between the treatments, the mean comparison test was performed using the multiple range test with Tukey's p<0.05 test. For data analysis, the statistical package Statgraphics Plus 5.0 was used. It was obtained as a result that the application of biostimulants increased soybean production, resulting significant with Fitomasplus, which achieved increases compared to the control of 25% and compared to FitomasEC of 22%, the Benefit/Cost ratio reported a positive effect of 1.02 for the FitomasEC and 1.25 for Fitomasplus with respect to the control.
Water - a foundation of dissipative regulation of a living organism
Authors: Orzhelskyi Igor , Kuznetsov Andrey
Published: February 2024

Dissipative processes of self-organization occur in both living and non-living matter. The same laws govern living and non-living matter, but the mechanism of their manifestation is different. The distinctive feature of living matter is "functional information," which is an attribute characteristic only of living matter. Functional information is a purposeful indication of the change in the structural-functional state of the living matter. Feedback plays an essential role in self-organization and the dynamic balance of dissipative systems. Self-organization is based on positive feedback (PF). Dynamic equilibrium of the system is ensured by negative feedback (NF). There is a constant competitiveness between the two types of feedback - PF and NF. In biological systems, the balance of PF and NF is maintained based on auto-oscillatory homeostasis processes. The regulatory function of homeostasis correlates with the dynamics of the ratio of free and bound water phases in the hydration-dehydration processes of biopolymers. Water regulates homeostasis and supports metabolism by maintaining the bound-free water phase ratio balance.
Approaches for sustainable production of soybean under current climate change condition
Authors: Fatima Aiman
Published: February 2024

Soybean is an important cash crop, cultivated worldwide for food, oil and feed production. Soybean production worldwide in 2020 was 353.5 million metric tons. This plant however, faces many challenges due to climate change. Increase in temperature, drought, floods etc. are the outcomes of climate change. These have a clear negative impact on soybean cultivation. This ultimately leads to food insecurity and economic losses. This review focuses on approaches which can be employed to address the climate change associated challenges in sustainable soybean production. The approaches like genetic engineering, aeroponics, nanotechnology, development of cultivars, plant pigments and hormones usage can be opted to help combat the impact of changing climate. Management of soybean under adverse climate change conditions will increase the yield and bring agriculture based economic prosperity.
Pretreatment of lignocellulosic biomass conversion into biofuel and biochemical: a comprehensive review
Authors: Siddique Mohammad , Nawaz Mengal Ali , khan Suleman , Ali khan Luqman , khan Kakar Ehsanullah
Published: February 2024

The most potential feedstock for industrial civilizations is lignin derived from biomass. The most prevalent aromatic polymer on earth and one of the most difficult materials for commercial application is lignin. Reducing sugars, which can be used to make biofuels and some other products, are among the many chemicals that lignocellulose biomass releases during pretreatment. Lignocellulosic material (LCMS) is a material that is easily accessible, renewable, recyclable, and plentiful. Sustainability has gained traction as a result of climate change and environmental harm. The need for a flexible strategy to meet rising global energy demands has led many academics to concentrate on renewable biofuel made from sustainable sources. Construction of industrial biorefineries using lignocellulose feedstock for biofuel production and other bioproducts. The effective and scalable valorization of lignin is one of the main issues. Its presence prevents the biochemical conversion of lignocelluloses into fuels and chemicals, which depends on the extraction of cellulose and hemicellulose. To produce sustainable energy, lignocellulosic biomass must undergo pretreatment to speed up fragmentation and reduce lignin content. Temperature, time, particle size, and solid loading are the controlling factors for lignin extraction. This study covers the working conditions, parameters, yield percentages, techno-economic evaluations, challenges, and recommended next steps for the direct conversion of biomass to hydrogen. It detailed how green pre-treatment techniques can be used to produce green biofuels, and prospects for the application of green pre-treatment technologies on an industrial scale are also provided. The sustainable lignocellulose biorefinery has a path forward thanks to effective lignin recovery and valorization techniques.