bluuebunny/crossref_metadata_2025 huggingface dataset:
Mengukur Peran Manajemen Pengetahuan, Human Capital, dan Inovasi dalam Memengaruhi Kinerja Guru [Measuring the Role of Knowledge Management, Human Capital and Innovation in Influencing Teacher's Performance]
Authors: Wijaya Octavia Marlene
Published: August 2022

The purpose of this research was to know the influence of knowledge management, human capital and innovation to the school’s performance at school X in Tangerang. The data collection was held using questionnaires from the populations of teacher in senior high school which was 42 teachers. The research methodology of this research was quantitative with path analysis to find the correlation between variables. The data processing used PLS-SEM method. The result of this research was that knowledge management influenced positively 0,690 to the human capital, knowledge management influenced positively 0,424 to the innovation, knowledge management influenced positively 0,185 to the performance of the organization, human capital influenced positively 0,533 to the innovation, and innovation influenced positively 0,698 to the performance of the organization. Human capital influenced negatively 0,018 to the performance of organization. This research found that there was a need of an improvement of human capital management especially in teacher’s turnover to avoid the loss of intangible asset, knowledge to maintain the performance of School X for long term. It was found that it was needed that the development of knowledge transfer as a part of knowledge management in School X to keep knowledge retention so in the future, the existed human capital would be able to produce innovation and maintain for the long term’s performance.
Fréquence des microfilaires canines dans le Sud du Nigeria
Authors: Uche U.E. , Odunze E.B.K.
Published: August 2022

Une étude a été conduite sur la fréquence des microfilaires dans le sang des chiens présentés à la consultation du centre hospitalier vétérinaire de l’Université de Nsukka et de la clinique vétérinaire d’Enugu. Elle a révélé que 9 des 200 chiens examinés étaient infestés, soit 4,5 %. Dirofilaria repens et Dipetalonema reconditum ont été identifiés. L’infestation était très sévère chez les mâles et chez les sujets âgés de 1 à 2 ans. Les Doberman Pinscher étaient les plus touchés, les chiens nigérians locaux l’étant le moins. Compte tenu de la pénurie d’informations en provenance du Sud Nigeria sur ce sujet, ces résultats s’inscrivent bien dans la ligne de l’importance croissante de la filariose canine, tant au point de vue clinique que comme zoonose.
Effet du traitement au lévamisole (L. tétramisole) sur la réceptivité des chèvres à la fasciolose à  Fasciola gigantica
Authors: Goraish I.A. , Abdelsalam E.B. , Tartour G. , Abbas B. , Aradaib I.E.
Published: August 2022

L’administration répétée d’un total de six doses hebdomadaires de lévamisole (L. tétramisole, 7,5 mg/kg S/C) s’est avérée augmenter la résistance à la fasciolose à Fasciola gigantica chez les chèvres. Cette résistance accrue a été révélée par une baisse du nombre de vers découverts à l’autopsie et par le développement de lésions hépatiques moins graves. L’élévation de l’activité enzymatique du plasma, de même que les dégradations du foie provoquées par Fasciola, étaient moins marquées chez les chèvres traitées au lévamisole. Le traitement au lévamisole était aussi associé à une plus grande réponse des anticorps contre l’infection à Fasciola gigantica.
Conduite de la reproduction en grands troupeaux laitiers dans les conditions marocaines. 1. Influence du programme d’action vétérinaire intégré de reproduction sur les bilans de fertilité
Authors: Lakhdissi H. , Lahlou Kassi A. , Thibier M.
Published: August 2022

La présente étude rapporte l’évolution comparée de divers paramètres de fertilité et de fécondité dans 4 grands troupeaux laitiers marocains pendant 4 années consécutives avant (les 2 premières années), puis pendant (les 2 dernières années) la mise en place d’un suivi de troupeaux adapté selon le Programme d’Action Vétérinaire Intégré de Reproduction (PAVIR). La mise en place de ce programme n’a pas modifié le taux de fertilité (56 % en première insémination naturelle-moyenne globale) ni le pourcentage de femelles ayant eu 3 inséminations ou plus (13 %). En revanche, il a notablement amélioré les performances de fécondité. L’intervalle vêlage insémination fécondante est passé de 150 jours en moyenne les premières années (avant la mise en place du programme) à 122 jours les 2 années suivantes. Les problèmes mal résolus de détection des chaleurs constituent encore un facteur limitant à l’amélioration ultérieure de ces troupeaux.
Etude des systèmes d’élevage bovin, traditionnel en Guadeloupe, Antilles françaises. Résultats d’enquêtes
Authors: Salas Michel , Planchenault Dominique , Roy F.
Published: August 2022

Dans le cadre d’un projet d’étude sur les systèmes d’élevage bovin traditionnel guadeloupéen, des enquêtes ont pu être effectuées sur 700 troupeaux dans tout le département. Dans un premier temps les différents paramètres de l’exploitation guadeloupéenne ont permis de différencier cinq types d’élevage. L’analyse actuelle des données apporte des informations sur la démographie et la structure des troupeaux, l’origine et la race des animaux ainsi que sur les paramètres de reproduction et de production. L’étude de ces paramètres a été faite pour chacun des types prédéterminés. Les animaux de « race, créole forment la quasi-totalité du cheptel bovin et présentent de très bonnes dispositions au plan de la reproduction, qualités incomplètement utilisées dans les systèmes d’élevage traditionnel (fertilité 72 p. 100, intervalle intervêlage de 16 à 17 mois, âge à la première saillie fécondante : 30 mois).
Etiologie des kératoconjonctivites des bovins. Recherche de Moraxella  chez les taurins N'Dama du Sénégal
Authors: Konté M.
Published: August 2022

L'auteur cherche à déterminer l'existence de la kératoconjonctivite infectieuse à Moraxella bovis chez les taurins sénégalais. L'étude est faite en saison sèche puis en saison des pluies. Les prélèvements sont effectués uniquement sur les animaux porteurs de kératoconjonctiv ite ou de larmoiement intense avec photophobie. L'observation clinique fait état d'une symptomatologie multiforme, affectant 3, 7 p. 100 des effectifs en saison sèche et 2, 27 p. 100 en hivernage. L'analyse bactériologique ne révèle à aucun moment Moraxella bovis; par contre, Acinetobacter calcoaceticus est mis en évidence dans 8, 9 p. 100 des cas cliniques en saison sèche et 1, 10 p. 100 en hivernage; le germe ne manifeste pas de pouvoir pathogène expérimental et serait simplement saprophyte.
Pouvoir attractif, pour  Glossina tachinoides , de produits chimiques isolés des odeurs animales
Authors: Mérot P. , Filledier J. , Mulato C.
Published: August 2022

Des expériences destinées à identifier les produits qui, dans l’odeur animale, sont attractifs pour Glossina tachinoides ont été entreprises par le CRTA de Bobo-Dioulasso, Burkina Faso. Des dérivés phénoliques ont partiellement simulé l’effet de l’odeur de bovin. L’adjonction d’octenol, pourtant inefficace seul, a potentialisé ce pouvoir attractif. Cela permet d’espérer, à moyen terme, la possibilité d’utiliser le piégeage avec attractif pour les glossines riveraines.
Investor Legitimate Expectation and Indirect Expropriation in Domestic Regulation Concerning the Application of Domestic Raw Application
Authors: Zaidun Muchammad , Yuniarti  , Widhayani Dian Pawestri
Published: August 2022

Law No 11/2020 concerning Job Creation (Omnibus Law’) mandates the use of domestic raw materials for all industries in Indonesia. Following the passage of the Omnibus Law, Indonesia issued Government Regulation No 28/2021 concerning Industrial Management and Presidential Regulation No 12/2021 concerning the amendment of Presidential Regulation No 16/2018 concerning Government Procurement of Goods and Services. Both regulations oblige all industries in Indonesia to use domestic raw materials pursuant to the Omnibus Law. In investment law, this kind of policy could lead to indirect expropriation because when an investor makes an investment in a host country, the raw material and machines for production might come from their home state or other states. Furthermore, a public-private partnership contract with investors funding infrastructure projects for at least 50 years using materials agreed upon in advance will lead to indirect expropriation. The method used in this research was legal research theory with statute and conceptual approaches. From this research, the policy of the Indonesian government can be described as indirect expropriation because the regulation is effective and enforced.
Reactive oxygen species in the progression and treatment of malignant mesothelioma
Authors: Cote Ava , Messier Terri , Cunniff Brian
Published: August 2022

Malignant mesothelioma (MM) is an aggressive cancer that affects the pleural and peritoneal mesothelial lining of the lungs and abdomen. Survival rates for patients with MM remain extremely low and effective treatments are limited. MM tumors harbor both genotypic and phenotypic features that indicate MM tumor cells are under increased oxidative stress, similar to other aggressive cancers. This increased oxidative stress in MM cells supports aggressive growth while providing a therapeutic vulnerability exploitable by redox-modulating compounds. MM tumor cells also exhibit altered mitochondrial structure and function that contribute to the disease through perturbations in metabolism and reactive oxygen species (ROS) production and metabolism. Targeting the altered redox status in cancer through increasing cellular ROS levels directly or inhibiting cellular antioxidant pathways and disrupting ROS scavenging mechanisms has become an exciting area for therapeutic intervention. This review discusses ROS sources and signaling, mitochondrial structure and function and targeting mitochondria ROS as a therapeutic approach for the treatment of MM.
Whether Chinese Primary School English Teacher Are Able to Help Students Learn With a Deep Approach
Authors: Wang Zhixuan
Published: August 2022

In order to improve the quality of education, there is a great concern for students’ learning methods. Students’ learning methods are basically divided into deep and surface methods. The deep approach is seen as the one that is encouraged to be used. However, in the views of the researchers, students in Asian countries tend to prefer to use surface methods of learning. Therefore, the authors would like to critically analyse an innovative teaching activities in a Chinese primary school to investigate whether Chinese primary school English teachers might be able to help their students achieve deep learning through changes in their classrooms.
A Literature Review of CSR Disclosure Quality: Evidence From Restatements
Authors: Yuan Taizhe
Published: August 2022

In the preceding 20 years, CSR reporting has made significant strides. This study examines the quality of CSR disclosure from the perspective of CSR restatements after reviewing prior literature. Long-term improvement in enterprises’ quality of CSR disclosure is believed to be made possible by more advanced reporting requirements, improved services from skilled auditors, and continuously evolving CSR reporting systems.
Identication and Classification of Menoreh Durians Based on Molecular - RAPD Markers
Authors: Nandariyah Nandariyah - , Yuniastuti Endang -
Published: August 2022

Menoreh durian is an accessions durian fruit originally from Kulonprogo district, Special Region of Yogyakarta, Indonesia. In the context of proposing Menoreh durian to be a new superior variety, it is necessary to have an identity and position in the molecular genetic group. The aim of the study was to obtain the identity and position of the of Menoreh Durian  in the molecular genetic classification. The wet laboratory experiment was using PCR-based RAPD method. Eleven accessions of durian were identified and characterized then grouped based on molecular analysis which were pink Menoreh and 3 Yellow Menoreh accsessions, Petruk, Sunan, Sukun, Sitokong, Montong, Kani and Aspar. The RAPD method was carried out in stages: DNA extraction, DNA quantity and quality test, amplification, electroforesis, visualization and analysis of results. The RAPD classification of 11 durian accessions , resulted in three groups; namely group I which consisted of Menoreh Kuning, Petruk, Aspar Sunan and Menoreh Jambon; Group II consisted of Montong, Sitokong, and Kani from Thailand; and group III consisted of only Sukun accession. Based on this grouping, Menoreh Kuning dan Menoreh Jambon which were separated from other groups at a genetic distance of more than 0.25 indicated that the accession of Menoreh Kuning and Menoreh Jambon only as variety.

 

 
Antibacterial Activity of Chayote (Sechium edule Swartz) Squash Extracts and Their Phytochemical Constituents
Authors: Sulistiyani Nur Indah , Ainurrofiq Ahmad , Suryanti Venty
Published: August 2022

Antibacterial activity of chayote (Sechium edule Swartz) squash extracts against pathogenic bacteria has been evaluated. Dried chayote squash powder was extracted using methanol which was then extracted successively using hexane, chloroform, ethyl acetate, and butanol. The antibacterial activities of the extracts were tested by the hole diffusion method. Methanol extract of chayote squash had antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, and Escherichia coli but did not have antibacterial activity against Enterobacter aerogenes, Shigella dysenteriae, and Salmonella typhi. Ethyl acetate extract had the highest antibacterial activity against P. aeruginosa and E. coli. The ethyl acetate extract contains phenolics, condensed tannins, flavonoids, and terpenoids. The ethyl acetate extract had a MIC of 50 mg/ml for S. aureus, B. subtilis, P. aeruginosa, and E. coli. Different bioactivities of tested extracts were found due to various chemical compositions of extracts as a result of different polarities of the solvent.
Coastal resilience : benefits of wrack and dune systems and current management practices
Authors: Provost Leigh , Bryant Mary , Eisemann Eve , Bryant Duncan
Published: August 2022

The purpose of this US Army Engineer Research and Development Center (ERDC) technical note (TN) is to review both the ecological and geomorphological impacts of wrack on dune systems and provide an overview of current beach dune and wrack management practices. As part of the US Army Corps Regional Sediment Management (RSM) Program, this TN also introduces a case study investigating wrack management solutions for dune stabilization.
Monkeypox in Pregnancy: Susceptibility, Maternal and Fetal Outcomes, and One Health Concept
Authors: Najimudeen Mohamed , Chen Hana W. Jun , Jamaluddin Nurul Akmal , Myint Myo Hla , Marzo Roy Rillera
Published: August 2022

An overlooked endemic zoonosis in Africa, monkeypox infection, which has spread to multiple non-endemic countries since early May 2022, was declared a Public Health Emergency of International Concern by the World Health Organization on July 23, 2022. As of August 8, 2022, over 28,000 confirmed and probable monkeypox cases were reported globally, including 6 deaths from the African continent and 4 deaths from the non-endemic regions. Although the current outbreak mostly belongs to the West African clade, which has a lower-case fatality ratio of <1%, there is limited data among immune-weakened individuals infected with monkeypox. It is still unknown if pregnant people are more susceptible to monkeypox. In addition, it is unclear whether having monkeypox increases the risk of birth defects. This commentary addresses reported cases of monkeypox infection in pregnancy and the possible maternal and fetal outcomes, including congenital monkeypox, miscarriage, or stillbirth. Factors behind the escalating global monkeypox outbreak, as well as the prevention and control of monkeypox via the One Health approach, are discussed to shed light on curbing the continuous emergence of monkeypox.
 
Copyright © 2022 Najimudeen et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.
Shallow Water: The Next Frontier for Deepwater Rigs, or Just a Passing Fad?
Authors: Jacobs Trent
Published: August 2022

Petrobras, one of the world’s top offshore operators, has shared new information about how it used an ultradeepwater rig in a place where it was never intended to work—in shallow water.

What makes its recent subsea campaign novel is that the Brazilian national oil company avoided mooring the rig and instead relied on dynamic positioning (DP).

Two key pieces of technology made this possible. The first is called a blowout preventer (BOP)-tethering system which sits on the seabed and absorbs much of the load being placed onto the wellhead structure. The second is a digital twin software that determines the safety of the rig’s position during drilling.

Petrobras is not the first to accomplish such a feat in depths less than 2,000 ft. But it is among the few to recount its learnings in multiple technical papers as it did at the recent Offshore Technology Conference (OTC) in Houston.

The fresh insights surrounding the Petrobras projects stem from an initial well drilled and completed 2 years ago with a sixth-generation drillship, the Norbe VIII, owned by Brazilian contractor Ocyan.

The new well is in the Albacora field within the Campos Basin and was the first of several planned to be drilled or plugged and abandoned by Petrobras in DP-only mode.

Over a 16-day period in May 2020, the Norbe VIII worked in water depths of about 1,475 ft where it successfully tapped into a pre-salt oil reservoir with a total depth of more than 16,000 ft.

For both firms, the project in the Campos Basin marked a first.

Never before had they used a rig in DP-only mode at such shallow depths, which amounted to about 15% of the rig’s maximum depth rating. Following the first well, Petrobras drilled at least one more in June 2021 in DP-only mode.

Notably, Petrobras was in the midst of selling off the Albacora field during its experimentation with DP-only shallow-water drilling. The mature asset was discovered by the state-run operator in 1984 about 75 miles from the coast and has been producing from post-salt reservoirs for the past 35 years.

But earlier this year, the company said it was hoping to fetch a higher price based on better-than-expected reservoir tests from the deeper pre-salt target it drilled in May 2020.
Field/Laboratory/Field Cycle Optimizes Fracture Placement, Well Performance
Authors: Carpenter Chris
Published: August 2022

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 204189, “8,070 Miles From the Field to the Laboratory and Back: A Pragmatic Sequencing of Laboratory- and Field-Based Fluid Testing and Quality Assurance/Quality Control—A Case History From Sichuan Region, China,” by A. Casero, SPE, A. Gomaa, and J. Ronderos, SPE, Titan Global Oil Services, et al. The paper has not been peer reviewed.

This paper illustrates comprehensive laboratory efforts undertaken to evaluate different high-viscosity friction reducers (HVFRs) and crosslinked gel products, their successful field application supported by a robust and effective field quality-assurance/quality-control (QA/QC) process, and the critical importance of maintaining an effective field/laboratory/field cycle to optimize fluid design and maximize results. A successful execution of several treatments in a challenging shale play in the Sichuan region of China achieved record proppant placements and, just as importantly, demonstrated repeatability and consistency over time, which had not previously been attained.

Geological Setting

The Sichuan Basin in southern China is a very active unconventional play targeting the Longmaxi Shale, a high-pressure/high-temperature shallow-to-deep marine shale deposited on top of the Baota limestone during the Late Ordovician and Early Silurian ages. The highly complex subsurface geomechanical environment is considered the main root cause of widespread casing deformation and associated challenges facing hydraulic fracturing.
Study Reviews Carbon-Capture Methods in Steelmaking Plants
Authors: Carpenter Chris
Published: August 2022

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper OTC 31540, “Comparative Review Study on Different Carbon-Capture Methods and Applications in Steelmaking Plants From an Economic Point of View,” by Thinesh S. Arul Rajoo, Khaled A. Elraies, SPE, and Ully Z. Husna, SPE, Universiti Teknologi Petronas, et al. The paper has not been peer reviewed. Copyright 2022 Offshore Technology Conference. Reproduced by permission.

The complete paper discusses carbon-capture processes and applications in the steelmaking industry from an economic point of view. Carbon capture is an expensive process, which can create hesitation in implementation. However, this process has not been properly quantified, which is the authors’ primary goal.

Introduction

The first portion of the complete paper describes the primary techniques used in carbon capture:

- Chemical absorption

- Physical absorption and membrane separation

- Precombustion

- Oxyfuel and partial oxyfuel combustion

- Direct air capture
Safety and feasibility of novel reconstruction method using long and narrow cobra- head- shaped gastric tube in laparoscopic proximal gastrectomy for cancer
Authors: Ueda Yoshitake , Kawasaki Takahide , Tanabe Sanshi , Suzuki Kosuke , Ninomiya Shigeo , Shiroshita Hidefumi , Etoh Tsuyoshi , Inomata Masafumi , Shiraishi Norio
Published: August 2022

Purpose.
To clarify the safety and feasibility of laparoscopic proximal gastrectomy (LPG) with our novel reconstruction methods, clinical outcomes of this LPG were evaluated and compared to those of LPG with our conventional method.
Methods.
Novel method is a reconstruction with a long and narrow gastric tube with widening of the proximal side of the gastric tube created by linear stapler. Esophagogastrostomy is performed by direct anastomosis with overlap method between the posterior wall of the esophagus and anterior wall of the gastric tube using a linear stapler. In conventional method, direct anastomosis between the esophagus and a gastric tube by a circular stapler was performed. Short- and long-term outcomes of a novel method were compared with those of conventional method.
Results.
A total of 39 patients whom LPG was performed were enrolled in this retrospective study. The amount of blood loss in the Novel method group (n = 30) was significantly less than those in the Conventional method group (n = 9) (40 vs. 110 ml, p < 0.01). No cases of anastomotic leakage and stenosis were observed in both groups. The cases of postoperative reflux esophagitis at 1 year after operation in the Novel group were less than those in the Conventional group (10% vs. 33%). In the Novel group, postoperative recurrence was observed in 2 patients (7%).
Conclusion.
LPG with novel reconstruction method using long and narrow cobra- head-shaped gastric tube can be easily performed, and may be feasible for the treatment of gastric cancer in the upper third of the stomach.
The Role and Value of In-Country African Instructors in International Experiential Training Programs; A Qualitative Case Study from the University of Minnesota
Authors: Nawagi Faith , Raman Aruna
Published: August 2022

Background: For effective delivery of International experiential training programs, many universities in the Global North, have created partnerships with universities in the global south especially in Africa to enhance their capacity and diversity of learning for their students. However, there is hardly any literature that exhibits the value and roles of African instructors in international experiential learning programs.Methods: This was a qualitative case study that examined the role of instructors and experts from Africa in influencing student learning processes and outcomes in the GCC 3003/5003 - Seeking Solutions to Global Health Issues. Semi-structured interviews with (2) students, (2)University of Minnesota lead faculty for the course, and (3) in-country instructors/experts from countries in East Africa and the Horn of Africa were conducted. Data was analyzed thematically.Results: The African In-country course instructors/experts describe themselves as “conduits” and “bridge builders,” filling gaps in knowledge for students, and “providing a true picture reflection of happenings on the ground.” Conclusions: In-country African instructors’ roles can be viewed as those aimed at validating students' ideas to apply to the local settings, streamlining students' focus, providing a platform for multi-stakeholder engagement to a particular topic coupled with bringing a real in-country context experience in the classroom.
A water reservoir on the Moon revealed by water diffusion in the Chang’e-5 impact glasses
Authors: He Huicun , Ji Jianglong , Zhang Yue , Hu Sen , Lin Yangting , Hui Hejiu , Hao Jialong , Li Rui-Ying , Yang Wei , Tian Heng-Ci , Zhang Chi , Anand Mahesh , Tartese Romain , Gu Lixin , Li Jin-Hua , Zhang Di , Mao Qian , Jia Li-Hui , Li Xiao-Guang , Chen Yi , Zhang Li , Ni Huaiwei , Wu Shitou , Wang Hao , Li Qiuli , He Huaiyu , Li Xian-Hua , Wu Fu-Yuan
Published: August 2022

The last decade of lunar exploration has revealed the presence of significant quantities of water on the Moon’s surface, notably characterised by global water retention, release, and replenishment1-9. This led to the proposition that a hydrated layer exists at depth in lunar soils, buffering a water cycle on the Moon globally9. However, so far no candidate reservoir has been identified for this hydrated layer. Here, we report the water abundances, hydrogen isotope compositions, and their core to rim variations, measured in impact glass beads from the Chang’e-5 (CE5) lunar soils. These targets preserve hydration signatures as revealed through water abundance profiles indicating diffusion of solar wind-derived hydrogen inwards into the glasses. Modelling suggests diffusion timescales of less than 661 years at a temperature of 296 K, which could provide an efficient mechanism to explain the recharge of water to sustain the lunar surface water cycle. We estimate that the amount of water contributed by impact glass beads in lunar soils can reach up to 7 × 1013 kilograms. These findings provide the first ground truths that could explain the water cycle at the Moon’s surface and demonstrate potential water reservoirs on airless bodies in the solar system.
Herbivore digestion as environmental filter - which seed traits help species survive?
Authors: Lepková Barbora , Mašková Tereza
Published: August 2022

Herbivorous animals are one of the vectors for seed dispersal of open-landscape plant species. The plant species are expected to be adapted to this type of dispersal and researchers presume they have specific seed traits. To find which traits help seeds survive the passage through digestion of wild herbivores, we conducted a comprehensive feeding experiment with almost forty species of plants and four species of herbivorous mammals. We fed specified numbers of seeds to the animals, collected the dung and germinated the dung content. We explored whether seed morphological traits and seed nutrient contents are good predictors of seed survival after passage through the herbivore digestive system. We also tested how the seed survival differed after the passage through different herbivore species. We found that species survival and germination success was positively correlated to seed nitrogen content and negatively to seed elongation. However, when we tested species from main families separately, i.e., legumes, grasses, and all other species, these trends changed directions. This suggests that seed dispersal by free-ranging wild herbivores is more a random process than driven by seed traits.
Dynamic Spectrum Access in Cognitive Radio Network using Static Neighbor Graph based prediction
Authors: S Mangairkarasi , D Arivudainambi
Published: August 2022

In Cognitive Radio Network (CRN), secondary users are allowed to access the licensed spectrum bands when it was not used by the primary user. The activities of the secondary users such as “how long to sense” and “how long to transmit” make a considerable intrusion into the quality of service of the secondary user due to dynamic spectrum access. Dynamic spectrum access techniques improve the efficiency of spectrum utilization. To alleviate the processing delay involved in spectrum utilization, spectrum prediction technique has been proposed for CRN. In this paper, an approach called Static Neighbor Graph (SNG) based prediction used for the prediction of the occupancy status of a primary user. Besides the prediction, the secondary user evades the sensing duty on busy channels which makes a considerable reduction in sensing time and energy consumption significantly. Along with SNG, the Carrier Sense Multiple Access/Collision Avoidance (CSMA/CA) is suggested for the coordination of the channel access to the secondary network. The performance of this proposed work has been illustrated and validated in terms of throughput, packet delivery ratio, and channel utilization.
Role of local Ru hexamers in superconductivity of ruthenium phosphide
Authors: Bozin Emil , Koch Robert , Aryal Niraj , Ivashko Oleh , Liu Yu , Aabeykoon Milinda , Bauer Eric , Zimmermann Martin v. , YIN WEIGUO , Petrovic Cedomir
Published: August 2022

Superconductivity in binary ruthenium pnictides occurs proximal to and upon suppression of a mysterious non-magnetic ground state, preceded by a pseudogap phase associated with Fermi
surface instability, and its critical temperature, Tc, is maximized around the pseudogap quantum critical point. By analogy with isoelectronic iron based counterparts, antiferromagnetic fluctuations became "usual suspects" as putative mediators of superconducting pairing. Here we report on a high temperature local symmetry breaking in RuP, the parent of the maximum-Tc branch of these novel superconductors, revealed by combined nanostructure-sensitive powder and single crystal X-ray total scattering experiments. Large local Ru6 hexamer distortions associated with orbital-charge
trimerization form above the two-stage electronic transition in RuP. While hexamer ordering enables the nonmagnetic ground state and presumed complex oligomerization, the relevance of pseudogap
fluctuations for superconductivity emerges as a distinct prospect. As a transition metal system in which partial d-manifold filling combined with high crystal symmetry promotes electronic instabilities, this represents a further example of local electronic precursors underpinning the macroscopic
collective behavior of quantum materials.
Ignition control and waste heat assessment of spontaneous combustion gangue hill by gravity heat pipe group: a case study in Shanxi Province, China
Authors: Zhou Xueyu , Guo Liangliang , Zhang Yongbo , Chang Ke
Published: August 2022

Spontaneous combustion gangue hill has attracted great attention due to serious environmental pollution and terrible geological disasters. However, the rich thermal resources inside are often ignored. In order to control the spontaneous combustion of gangue hill and utilize the internal waste heat resources, this project studied the combined treatment effect of 821 gravity heat pipes, laid 47 sets of temperature monitoring devices, evaluated the storage of waste heat resources and proposed different waste heat utilization methods. The results show that: (1) The positions of spontaneous combustion are all located on the windward slope. The highest temperature is in the range of 6m~12m underground, exceeding 700 ℃. (2) The single-tube experiment of gravity heat pipe shows that the effective temperature control radius is 2m. The cooling effect is obvious in the range of 3m~5m underground. However, the temperature rises at the depth of 1 m underground. (3) After 90 days of treatment of the gravity heat pipe group, the temperature at the depths of 3m, 4m, 5m and 6m in the high temperature zone dropped by 56℃, 66℃, 63℃ and 42℃ respectively. The maximum temperature drop exceeds 160℃. The average temperature drop in the middle and low temperature areas is between 9°C and 21°C. (4) The concentration of harmful gases (CO, SO2and H2S) decreases by more than 90%. The hazard level is greatly reduced. (5) The amount of waste heat resources contained within ten meters of the spontaneous combustion gangue hill is 7.83E13J. Waste heat resources can be used for indoor heating and greenhouse cultivation. And, under the temperature difference of 50 °C, 100 °C and 150 °C, the electric energy generated by the heat through the thermoelectric conversion device in the high temperature zone of the gangue hill is 4056.8 kW·h, 7468.2 kW·h and 10603 kW·h, respectively.
Visual prognosis and surgical timing of Ahmed glaucoma valve implantation for neovascular glaucoma secondary to diabetic vitrectomy
Authors: Lee Jong Suk , Lee Young Bok , Kim Tae-Woo , Park Kyu Hyung
Published: August 2022

Background: Evaluate the visual outcomes of Ahmed glaucoma valve implantation (AGVI) in patients with neovascular glaucoma (NVG) who underwent diabetic vitrectomy and suggest appropriate AGVI timing.Methods: Medical records of patients who underwent AGVI due to NVG after diabetic vitrectomy were reviewed. Successful intraocular pressure (IOP) control was defined as an IOP between 6 and 21 mmHg. Visual outcome was compared before NVG diagnosis and after AGVI, and the “unfavorable visual outcome” was based on 0.3 LogMAR unit of best corrected visual acuity (BCVA). Various factors including surgical timing were evaluated to identify the risk factors associated with unfavorable visual outcome. Results: A total of 35 eyes were enrolled and divided into group 1(medically uncontrolled NVG group, 16 eyes) and group 2(NVG group responded well to the initial non-surgical treatment but eventually required AGVI, 19 eyes). Despite the favorable rate of normalization of post-AGVI IOP (85.7%), 43.8% in Group 1 and 26.3% in Group 2 showed unfavorable visual outcomes. In group 1, delayed surgical timing of AGVI showed a significant association with unfavorable visual outcomes (P = 0.041). In group 2, poor patient compliance was the main factor of unfavorable visual outcomes.Conclusions: When NVG occurs in patients with proliferative diabetic retinopathy after vitrectomy, physicians should be cautious not to delay the surgical intervention, especially in patients with IOP of 30 or more despite non-surgical treatment. Early AGVI within six days might be necessary to preserve useful vision in these patients.
Young Generations' Hopelessness Perpetuates Long-term Conflicts
Authors: Hasler Béatrice S. , Leshem Oded A. , Hasson Yossi , Landau Daniel H. , Krayem Yara , Blatansky Chen , Baratz Guy , Friedman Doron , Psaltis Charis , Cakal Huseyin , Cohen-Chen Smadar , Halperin Eran
Published: August 2022

Transforming long-term conflicts into peaceful intergroup relations is one of the most difficult challenges for humanity. Such meaningful social changes are often driven by young people. But do young people living in contexts of long-term conflicts believe that change is even possible? In a series of six studies (Ntotal= 119,671) over two decades and across two unrelated intractable conflicts in Israel/Palestine and Cyprus, we found that younger (compared to older) generations from both respective rival groups have less hope for peace, and consequently less conciliatory attitudes. We also show that this gradual improvement of peace-promoting emotions and attitudes with increasing age can be experimentally accelerated in young people through a virtual reality-based aging simulation. These findings provide a new perspective on the fundamental question of why long-term conflicts are so difficult to resolve and highlight the importance of instilling hope in young generations to advance peace processes.
Factors associated with acute kidney injury among preterm infants administered vancomycin: A retrospective cohort study
Authors: Shin Baek Sup , Shin Seung Han , Park Seul Gi , Kim Ee-Kyung , Kim Han-Suk
Published: August 2022

Background
Vancomycin (VCM) is a widely used antibiotic for the treatment of gram-positive microorganisms, with some nephrotoxic effects. Recent studies have suggested that piperacillin-tazobactam (TZP) aggravates VCM-induced nephrotoxicity in adults and adolescents. However, there is a lack of research investigating these effects in the newborn population. Thus, this study aimed to investigate whether the concomitant use of TZP with VCM use increases the risk of acute kidney injury (AKI) and to explore the factors associated with AKI in preterm infants treated with VCM.
Methods
This retrospective study included preterm infants with birth weight < 1,500g in a single tertiary center who were born between 2018 and 2021 and received VCM for a minimum of 3 days. AKI is defined as a minimum increase in serum creatinine (SCr) of 0.3 mg/dl and an increase in SCr of at least 1.5 times the baseline. The study population was categorized as those with or without concomitant use of TZP. Data on perinatal and postnatal factors associated with AKI were collected and analyzed.
Results
Of the 70 infants, 17 died before 7 postnatal days or antecedent AKI and were excluded. Among the remaining participants, 25 received VCM with TZP (VCM + TZP) and 28 patients VCM without TZP (VCM-TZP). Gestational age (GA) at birth (750.4 ± 232.2 vs 838.1 ± 268.7, p = 0.212) and birthweight (26.5 ± 2.6 grams, p = 0.859) were comparable between the two groups. There were no significant differences in the incidence of AKI between groups. Multivariate analysis showed that GA (adjusted OR: 0.58, 95% CI: 0.35–0.98, p = 0.042), patent ductus arteriosus (PDA) (adjusted OR: 5.23, 95% CI: 0.67–41.05, p = 0.115), and necrotizing enterocolitis (NEC) (adjusted OR: 37.65, 95% CI: 3.08–459.96, p = 0.005) were associated with AKI in the study population.
Conclusions
In very low birthweight infants, concomitant use of TZP did not increase the risk of AKI during VCM administration. Instead, a lower GA, PDA, and NEC were associated with AKI in this population.
Pre-clinical efficacy of CD20-targeted chimeric antigen receptor T cells for non-Hodgkin's lymphoma
Authors: Wen Hairuo , Lou Xiaoyan , Qu Zhe , Qin Chao , Jiang Hua , Yang Ying , Kang Liqing , Geng Xingchao , Yu Lei , Huang Ying
Published: August 2022

Background:A 4-1BB/CD3-ζ-costimulated CAR-T against CD20 (CAR-T20) was subjected to a systemic efficacy evaluation in a cell coculture model, and NOD-SCID IL-2 receptor gamma null mice (short for NSG mice) were xenografted with human Burkitt's lymphoma Raji cells.Methods:CAR-T20 cells were incubated with target cells (K562, K562 CD20 or Raji cells) at ratios of 10:1 and 5:1 for 24 h, and the killing rate was estimated by an LDH cytotoxicity assay. To evaluate the effect of CAR-T20 on the survival time of tumor-bearing animals, 30 NSG mice were employed, and Raji-Luc cells (5×105cells per mouse) were administered prior to CAR-T20 administration. The survival time, optical intensity of Raji-Luc cells, clinical symptoms, and body mass of the animals were observed. Another 144 male NSG mice were employed to investigate the proliferation and antitumor effects of CAR-T20. Human cytokine and murine cytokines were detected at 1, 7, 14, 21, 28, 42, 56 and 90 days post-CAR-T administration, while biochemistry index analysis, T-cell and CAR-T-cell detection in peripheral blood, and histopathological examination were performed at 14, 28, 56 and 90 days post-administration.Results:CAR-T20 cells had a specific killing effect on CD20-expressing cellsin vitro. At a dose of 1×106per mouse or above, CAR-T20 prolonged the median survival time from 14 days to more than 3 months, inhibited the proliferation of Raji cells in mice, and alleviated the clinical manifestations and weight loss caused by the Raji-Luc cell load. CAR-T20 at a dose of 2×106per mouse or above inhibited the proliferation of Raji cells in mice for up to 111 days post-administration without recurrence. The numbers of T cells and CAR-T cells in the animals administered CAR-T20 increased significantly when Raji cells were markedly proliferated and subsequently decreased when Raji cells were predominantly inhibited. CAR-T20 increased human IFN-γ, murine TNF and murine IL-6 levels and decreased human IL-10 levels in tumor-bearing mice. The incidences of xenografted tumors in organs/tissues were also reduced effectively by CAR-T20.Conclusion:The effective dose of CAR-T20 in mice starts from 1×106per mouse, equivalent to a clinical dose of 5×106/kg. Together, our data support the clinical translation of CAR-T20 for R/R B-cell NHL patients.
Tumor–stroma ratio, predict the prognostic and PD-L1 expression in hepatocellular carcinoma
Authors: Wang Dong , Luo Jia , Tao Yiming
Published: August 2022

Background: With the depth research of tumor microenvironment, tumor stroma was considered to play a leading role in the tumor malignant behavior, the PD-L1 was also related with the tumor stroma. Tumor–stroma ratio (TSR) has already been regarded as a novel prognostic factor in many cancers. Our study aims to assess the TSR and PD-L1 clinical value in the HCC patients. Material and methods: 95 patients who diagnosed HCC, were included in our res. TSR was estimated on HCC specimen HE sections, and the optimal TSR cut-off value was determined by ROC curves. The correlation between TSR and clinicopathologic features was also culculated. Immunohistochemistry staining was also carried out to analysis the PD-L1 expression levlel in HCCs. Results: The optimal TSR cut-off value was 0.525. The median OS of the stroma-high and stroma-low groups was 27 vs. 36 momths. The median RFS of the stroma-high and stroma-low groups was 14.5 vs. 27 months. In Cox multivariate, TSR was an independent prognostic factor in HCCs overall survival (OS) and recurrence free survival (RFS) who underwent liver resection. Immunohistochemistry (IHC) staining revealed that TSR-high HCC samples with high PD-L1-positive cells expression. Conclusions: Our results suggest that TSR can predict the prognosis in the HCCs who underwent liver resection, the TSR has relation with the PD-L1 expression and may be the therapy target which can dramatically improve the HCC patients’ clinical outcomes.
Revealing the potential of Guianese waste fibers from timber production and clearings for the development of local and bio-based insulation fiberboards.
Authors: Bossu Julie , Moreau Jérome , Delisée Christine , Moigne Nicolas Le , Corn Stéphane , Sonnier Rodolphe , Viretto Amandine , Beauchene Jacques , Clair Bruno
Published: August 2022

In French Guiana, the development of bio-circular value chains to convert residual biomass into insulation fiberboard represents a promising opportunity to build energy-efficient houses. The objectives of this work are to select and characterize resources of interest and discuss the relationships between fiber properties, manufacturing parameters and fiberboards performances. Five local wood and bark residuals fibers are fractionated and fractions are analyzed by laser granulometry, thermal gravimetric analysis (TGA) and pyrolysis combustion flow calorimeter (PCFC). Fiberboards are produced using a thermomechanical process and their microstructure, thermal and sorption properties are characterized by X-ray microtomography, hot plate technique, and dynamic vapor sorption (DVS). Morphological analysis shows that large and elongated wood fractions allow the formation of thick and cohesive fibrous networks, while the bark small-sized fractions are more difficult to process, requiring more compaction and synthetic fibers as additives. However, despite processing difficulties, bark fiberboards show the best insulation performances, comparable to commercial reference products. In addition, TGA and PCFC tests reveal that bark fibers show better thermal stability and fire behavior compared to wood. Finally, they also show a strong affinity for water, highlighting the need for further investigations on their ageing under tropical conditions of use.
Targeting Labile Iron-Mediated Ferroptosis on Renal Proximal Tubular Epithelial Cells Provides a Potential Therapeutic Strategy for Rhabdomyolysis-Induced Acute Kidney Injury
Authors: Cao Ji , Haiying Zhu , Cen Jie , Hong Chenggang , Wang Haiyang , Wen Yuanmei , He Qiaojun , Yu Yongping , Chen Wenteng
Published: August 2022

Acute kidney injury (AKI) is a global health problem and occurring in a variety of clinical settings. Despite some advances in supportive clinical care, no medicinal intervention has been demonstrated to reliably prevent AKI so far. Thus, it is highly demand to investigate the involved pathophysiology and mechanisms, as well as discover therapeutics on the basis. In this work, an upregulated mRNA level of ferroptosis biomarkers (Ptgs2 and Acsl4), and an elevated renal iron and malondialdehyde (MDA) level were observed in the early stage of murine rhabdomyolysis induced-AKI (RM-AKI), which support a pathogenic role of labile iron-mediated ferroptosis and provide a chance of utilizing iron chelation for RM-AKI preventions. Given that the existing small molecule-based iron chelators did not show promising preventions against RM-AKI, we further designed and synthesized a new hydroxypyridinone-based iron chelators for potently inhibiting labile iron-mediated ferroptosis. And a lead AKI-02 was identified with remarkable protection of renal proximal tubular epithelial cells from ferroptosis and excellent iron chelation ability. Moreover, administration of AKI-02 led to a recovery of renal function, which was substantiated by the decreased BUN and creatinine, as well as reduced labile iron level and improved histopathology. Thus, our studies highlighted the targeting labile iron-mediated ferroptosis as a therapeutic benefit against RM-AKI.
Water-food-energy nexus in global cities: solving urban challenging interdependencies together
Authors: Hachaichi Mohamed , Egieya Jafaru
Published: August 2022

Understanding how water, food, and energy interact in the form of the water-food-energy (WFE) nexus is essential for sustainable development which advocates enhancing human well-being and poverty reduction. Moreover, the application of the WFE nexus has seen diverse approaches to its implementation in cities across the globe. There is a need to optimize knowledge sharing to improve urban information exchange focused on the WFE nexus’ application and impact on the UN Sustainable Development Goals. In this study, Natural language processing (NLP) and affinity propagation algorithm are employed to explore and assess the application of the WFE nexus on a regional basis as well as at city levels. The results show that after the exhaustive search of a database containing 32,736 case studies focusing on 2,233 cities, cities with the most potential to encounter resource shortages (i.e. WFE limitation) are systematically underrepresented in literature (African and Latin American cities). Hence, with regional and topic bias, there is a potential for more mutual learning links between cities that can increase WFE nexus policy exchange between Northern and Southern hemispheres through bottom-up case-study knowledge. In addition, this study shows that Southern hemisphere cities can benefit from knowledge transfer because of their limited urban intelligence programs.