bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of Electromagnetic Wave Propagation in Triple Walled Carbon Nanotubes
Authors: Basmaci Ayşe Nihan , Filiz Seckin
Published: February 2024

This study examines the behavior of electromagnetic wave propagation in a unique and complex three-walled carbon nanotube structure. The structure is formed by nesting three distinct nanotubes, and the interactions between them are thoroughly analyzed, taking into account their varying electromagnetic, material, and nano properties. The structure is designed at a nanoscale to provide a comprehensive description of electromagnetic wave propagation, including the electromagnetic interaction between the second nanotube, located in the middle of the structure, and the other two nanotubes situated in both the inner and outer portions of the structure. This study presents novel findings that differ from existing literature on the subject, contributing to our understanding of this important area of research.
Effects of Selective Serotonin Reuptake Inhibitors Exposure in Stressed Pregnant Mice on the Anxiety Behavior of the Offspring
Authors: Ardianto Chrismawan , Aprilia Pingkan , Rahmadi Mahardian , Sumartha I Nengah Budi
Published: February 2024

Background: Stress hurts problem-solving abilities, while anxiety disorders and depression are associated with unpleasant feelings and impaired daily functioning. Open field test (OFT) is used to assess anxiety-like behavior in animals by observing their exploratory behavior. Pregnant women are vulnerable to stress, which increases the risk of premature birth and low birth weight. Stress during pregnancy can also lead to preeclampsia and behavioural problems in newborns. Selective serotonin reuptake inhibitors (SSRIs), commonly used antidepressants during pregnancy, help manage mental disorders by increasing serotonin levels and regulating the endocrine system. They reduce glucocorticoid levels, thereby alleviating anxiety and stress in pregnant women. Objectives: This research investigates the correlation between the administration of SSRIs to stress-induced expectant mothers, the manifestation of depression-like behaviour, and the expression of glucocorticoid receptors in the offspring's hippocampus. Material and Methods: This study included four mouse groups: control without stress, control with offspring stress, stress model with footshock on dams and o ffspring, and stress with fluvoxamine treatment. Depressive and stress-related behaviors were measured using OFT. Results: OFT was used to assess the behaviour of offspring mice. Significant differences were observed in the number of crossings in the centre area and behaviour. The SSRI treatment showed potential anxiolytic effects, while stress led to reduced behaviour. These findings contribute to understanding anxiety-related responses and the effects of stress and SSRI treatment in animal models. Conclusions: OFT revealed significant differences in anxiety behaviour, specifically in the number of crossing centres, the centre area, and behaviour. SSRI treatment exhibited anxiolytic effects, while stress-decreased behaviour findings enhanced our understanding of anxiety responses and the impact of stress and SSRI treatment in animal models.
Detecting Location Errors with ERA5 Pseudo Stations
Authors: Bezeau Clara , Geissel Elizabeth , Hayes Emily , Miria Gertrude , Platt Connor , Whelan William , Yang Teng , Thorne Peter
Published: February 2024

Significant efforts are made to eliminate biases from models and
observations, especially at operational centres. However, these biases
still significantly impact the quality of assimilated data products. In
the case of numerical weather prediction, residual biases can result in
suboptimal utilization of available data or even render them unusable.
In climate research based on re-analyzed datasets, it can be difficult
to distinguish between accurate signals and trends from inaccurate ones
caused by biases in models and data.This study used a detection
algorithm written in the R language to perform statistical computing and
data analysis. The algorithm was applied to a synthetic study utilizing
pseudo-stations based on ERA5 to simulate and detect instrumental
effects. Rather than using observational data from real-world sources,
the study generated artificial scenarios to guarantee the quality of the
data assessment.ERA5 is a well-known atmospheric reanalysis product that
was used to create simulated or pseudo-weather stations. These stations
were designed to mimic actual stations but were generated
computationally to enable controlled experimentation. The study
constructed twenty-five pseudo-stations in Frankfurt, Germany, within
the latitude 49–50° and longitude 8–9° in the Northern Hemisphere. The
study utilized the ERA5 land surface dataset of hourly 2-m air
temperature of September in 2013 and 2014. The study tool significantly
improves data quality assessment by evaluating the synthetic dataset’s
precision, dependability, and general robustness. It introduces a range
of factors to assess the degree to which the data quality can be
enhanced and maintained, including station movements, errors, and
noise.To determine the likelihood of the threshold correlation occurring
at our confirmed noise threshold, the correlation values occurring at
1.53 for each locational trial were extracted. Our threshold correlation
was evaluated to see if it occurred within a likely range of
correlations occurring at 1.53 degrees of noise, where 0.9744052 is less
than 0.9744667 but greater than 0.9781093. This process helps improve
detection methods for data anomalies, contributing to advancements in
data quality assessment.
Digital Transformation of Tax Administration in the Republic of Korea: Lessons from Experience and Ways Forward
Authors:   Development Research in the Center for International Development, Kim Daeyong
Published: February 2024

This governance brief details the digitalization of the Republic of Korea’s (ROK) tax administration, assesses how its strategy can bolster tax revenues, and explores how developing countries can replicate its strategy to roll-out e-taxation models.
Resolving Demand-Side Issues in Electric Vehicle Financing in India
Authors: Sinha Sudhendu , Teja Joseph , Acharya Jiwan Sharma , Challa Keerthi Kumar , Koparkar Prasad , Sharma Vivek , Srinivasan Ajay , Thakkar Hemal N.
Published: February 2024

This working paper presents an overview of the electric vehicle (EV) financing landscape in India, along with suggestions on how to enhance financing options and services to promote the adoption of EVs. The key proposal involves offering a credit guarantee to instill confidence in lenders and enable them to finance EVs at competitive interest rates and loan-to-value ratios, comparable to those offered for traditional internal combustion engine vehicles.
Efficacy of focused shockwave therapy in patients with moderate-to-severe carpal tunnel syndrome: a preliminary study
Authors: Vongvachvasin Pimpisa , Phakdepiboon Thitiporn , Chira-Adisai Waree , Siriratna Punpetch
Published: February 2024

Objective: To evaluate the efficacy of focused extracorporeal shockwave therapy for symptoms and function in patients with moderate-to-severe carpal tunnel syndrome.
Design: A single-blind randomized controlled trial.
Subjects: Twenty-four outpatients with moderate-to-severe carpal tunnel syndrome.
Methods: Patients were randomly allocated into 2 groups: a focused extracorporeal shockwave therapy group and a control group. The focused extracorporeal shockwave therapy group received conservative treatment in addition to focused extracorporeal shockwave therapy with an energy flux density ranging from 0.01 to 0.15 mJ/mm2, a frequency of 4–5 Hz, and 1500 pulses per session once a week for a total of 3 sessions. The control group received only conservative treatment, which comprised gliding exercises for carpal tunnel syndrome, a night wrist splint, and lifestyle modification. The Thai version of the Boston Carpal Tunnel Questionnaire (T-BCTQ), a nerve conduction study, and ultrasonography of the median nerve cross-sectional area were performed before treatment and at 3 and 6 weeks after baseline.
Results: The T-BCTQ symptom and function scores had significantly decreased in both groups, favouring focused extracorporeal shockwave therapy at all time-points. In addition, distal sensory and motor latency were significantly different between the groups at 3 weeks from baseline.
Conclusion: Focused extracorporeal shockwave therapy plus conservative treatment effectively provided short-term improvement in symptoms, hand function, and nerve conduction in patients with moderate-to-severe carpal tunnel syndrome compared with conservative treatment alone.
Baltic Amber in Hungarian Bronze Age. New data and current stage of research
Authors: Jaeger Mateusz , Kulcsár Gabriella , Melis Eszter , Stróżyk Mateusz , Piszora Paweł , Csányi Marietta , Csuvár-Andrási Réka , Fischl Klára P. , Guba Szilvia , Pap Evelin , Pásztor Emília , Patay Róbert , Szathmári Ildikó , Szilas Gábor , Čivilytė Agnė , Kiss Viktoria
Published: February 2024

Amber was one of the key raw materials distributed in Bronze Age Europe. One of its varieties – succinite – wasexchanged over a vast area stretching from its sources on the southern shores of the Baltic Sea to the shores of the Mediterranean Sea. The chemical identification of Baltic amber significantly expands our knowledge of the dynamics and nature of the relationships connecting different regions of Europe in the first half of the second millennium BC. One of the most significant cultural-geographical areas reached by this amber was the Carpathian Basin. This text presents a summary of the current state of knowledge about the context, chronology, and the extent of amber occurrence in the Hungarian Bronze Age. At the same time, it supplements the catalogue of finds with artefacts acquired in recent years, providing new information regarding radiocarbon dating and spectral analysis of selected amber artifacts.
Human Papilloma Virus: Emerging Risk Factor in Oral Squamous Cell Carcinoma among Asians
Authors: RMSHB Medawela
Published: February 2024

Oral and oro-pharyngeal cancer grouped together is the 6th most common cancer in the world. Annual estimated global incidence is around 300373 for oral cancer (GLOBOCAN 2012).
Historiography of Immunology in Oral Pathology-A Concise Review
Authors: Bommanavar Sushma
Published: February 2024

The historiography of immunology has become a bustling, pluripotent discipline, and continues to develop in many new and exciting directions that include immunohistochemistry and immunopathology in the field of Oral pathology. Immunology, the science that studies the structure and functioning of the immune system, began long before anyone knew about disease causing microbes or even that individuals had an immune system that protected the body against disease. In the field of Oral pathology, one encounters various immunological diseases in routine day-to-day practice, hence having the complete knowledge on this aspect which many a times is overlooked, is of utmost importance for proper investigations and latest research in this field that in turn comes from the past historical knowledge. The terminology and techniques today have the foundation in the past. The historical considerations of past events give perspective to the present programmes and direction for future development. Hence, the present review is a good starting point for compiling the historiography of immunology in the field of Oral pathology and includes a short compilation of the past historical background about basic immunology, hypersensitivity and autoimmunity. In addition, future consideration of this discipline in Oral pathology should be emphasized and targeted.
Pemanfaatan Augmented Reality untuk Keterampilan Komunikasi Sosial Anak dengan Gangguan Spektrum Autisme
Authors: Wagino  , Sujarwanto  , Niratama Fairus
Published: February 2024

Gangguan spektrum autisme (ASD) adalah gangguan neurologis yang menyebabkan anak yang didiagnosis mungkin menghadapi kesulitan dalam komunikasi sosial atau memiliki serangkaian perilaku yang berulang atau terbatas.  Tujuan penelitian ini untuk menganalisis pemanfaatan augmented reality untuk keterampilan komunikasi sosial anak dengan gangguan spektrum autisme. Jenis penelitian ini merupakan penelitian kualitatif. Pengumpulan data dengan menggunakan metode kualitatif maupun kuantitatif. Subjek penelitian terdiri dari berbagai kelompok usia dan tingkat keparahan dan harus mencakup kedua jenis kelamin. Hasil penelitian menunjukkan efek penggunaan AR terhadap pembelajaran individu adalah positif. Namun, mengingat beragam keterampilan yang ditargetkan dalam studi terpilih, dan heterogenitas peserta, kesimpulan sumatif mengenai keefektifan AR untuk mengajarkan keterampilan komunikasi sosial kepada individu dengan ASD berdasarkan literatur yang ada tidak mungkin dilakukan. Kefektifan relatif AR di antara lebih banyak peserta, teknologi berbeda yang mendukung AR, intervensinya, dan evaluasi di lingkungan kelas diperlukan. Penelitian ini memberikan wawasan tentang solusi berbasis augmented reality (AR) yang dikembangkan untuk gangguan spektrum autisme (ASD).
Hematological values of captive Indotestudo travancorica (Boulenger, 1907) and Batagur kachuga (Gray, 1931): a short communication
Authors:   Mypetclinic, Milano, Italy, Bardi Edoardo , Lubian Emanuele , Romussi Stefano , Whitaker Nikhil , Giordano Alessia
Published: February 2024

The Indian subcontinent is home to many species of herpetological and conservation interest. The aim of this study was to provide a first assessment of hematological values in Travancore tortoises (Indotestudo travancorica) and redcrowned roofed turtles (Batagur kachuga), two endangered species on which medical literature is still lacking. In late spring, 19 blood specimens of healthy I. travancorica and 17 of B. kachuga were sampled. Both populations were housed at the Madras Crocodile Bank Trust – Centre for Herpetology (Tamil Nadu, India). From each animal, a blood sample was obtained from the dorsal coccygeal vein and stored in a lithium-heparin test tube. For both species, manual red and white blood cell counts (RBC and WBC) were performed using a Natt & Herrick stain in a Neubauer chamber. Only for I. travancorica, hematocrit values were assessed by centrifugation of capillary tubes, and used to calculate mean corpuscular volume; this investigation was not performed on B. kachuga due to equipment malfunction. Due to the small sample size, only descriptive statistics were applied, and the obtained values were compared with the known references of other chelonians. Only for B. kachuga, the composition of the sampled population made it possible to run cross sectional comparisons between adult and juvenile individuals, as well as between males and females. No difference was found between males and females, but a significant difference (P<0,05) was found for WBC counts between juvenile and adult animals.
Phenotypic and genotypic investigation of antimicrobial resistance and extended-spectrum beta-lactamase production among Escherichia coli isolated from bovine mastitis
Authors:   Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran, Aflakian Fatemeh , Mohseni Niloufar , Hafiz Maryam , Nikoueian Helia , Askari Badouei Mahdi , Rafati Zomorodi Abolfazl
Published: February 2024

Escherichia coli has been one of the most highlighted pathogens isolated from clinical cases of mastitis. Unfortunately, the deficiency of appropriate antimicrobial stewardship and overuse of antimicrobial agents have increased antimicrobial resistance in animal isolates. The current study aimed to demonstrate the prevalence of extended-spectrum beta-lactamase (ESBL) production, resistance genes, and multi drug resistant (MDR) among E. coli isolates from cases of clinical mastitis. For this purpose, 40 E. coli isolates were collected from clinical mastitis milk samples from five farms in Mashhad, Iran. The antimicrobial susceptibility testing (AST) was applied to 15 antimicrobial agents of veterinary and human medicine interest. Also, ESBL production was evaluated using a doubledisc synergy test (DDST). The distribution of 20 resistance genes was sought among E. coli isolates by six multiplexPCR and three uniplex-PCR assays. The highest sensitivity was identified against imipenem and amikacin (100%). On the other hand, the highest resistance was observed for tetracycline and trimethoprim-sulfamethoxazole (70% - 72.5%), respectively. According to the AST and DDST tests, one isolate was confirmed as ESBL-producing and MDR. In addition, the most frequent resistance genes were blaTEM and AmpC (100% each). The qnrA encoding resistance to quinolones was similarly prevalent and detected in 50% of the isolates. In conclusion, at least three resistant genes were detected in 28 isolates (70%), but the majority of isolates were sensitive against most of the tested antibiotics. This fact might relate to the low expression of these genes within the isolates. The horizontal gene transfer of the present genes may confer resistance to other related bacterial species in humans or domestic animals.
The effect of seaweed formulations on in vitro fermentation, nutrient utilization and growth performance in crossbred calves
Authors:   Animal Nutrition Division, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India, Handique Bornalee , Singh Putan , Kumar Verma Ashok , Yengkhom Rojita
Published: February 2024

The aim of this research was to study the effect of seaweed formulations on in vitro rumen fermentation, nutrient utilization and growth performance of crossbred calves. The study included 18 male crossbred calves of 130±7.56 kg body weight, divided into 3 groups of 6 each following a completely randomized design. Calves in the control (T0) were fed a standard diet, while treatment groups T1 and T2 were supplemented with AF-KWP or AFRD-5 at the rate of 4% of concentrate mixture, with 1% calcium carbonate and 1% dicalcium phosphate replacing the mineral mixture, and common salt offered in T0 . The experiment was conducted for a period of 120 days. At the end of the experiment, a metabolism trial was conducted to study the nutrient utilization. In vitro total gas and methane production was significantly (P<0.05) lower in the seaweed supplemented groups. A significant difference (P<0.05) was also observed in the retention of calcium and phosphorus between the different groups. A non-significant difference was observed in nutrient digestibility, dry matter intake, total gain in body weight, average daily gain and feed conversion ratio between the three treatment groups. It might be concluded that seaweed formulations significantly reduced in vitro total gas and methane production without affecting true dry matter digestibility and true organic matter digestibility. Moreover, seaweed formulation supplementation did not affect the growth performance and nutrient utilization in the crossbred calves.
Coxiella burnetii occurrence in dairy herds in Gabrovo Region, Bulgaria, evaluated by serological and molecular analyses of bulk-tank milk samples
Authors:   National Diagnostic and Research Veterinary Medical Institute “Prof. Dr. G. Pavlov”,  Department of epizootology and animal infectious diseases, Sofia, Bulgaria, Borisov Simeonov Konstantin , Genova-Kalou Petia Dinkova
Published: February 2024

This study investigated the occurrence of Coxiella burnetii in dairy cattle, goat herds and sheep flocks in the Gabrovo Region, central Bulgaria, to identify the potential sources of Coxiella burnetii infection diagnosed in veterinarians and farm workers in this region. To detect infection on livestock farms, we tested bulk-tank milk (BTM) for the presence of antibodies and/or the Coxiella burnetiid genome using ELISA and PCR, respectively. A total of 81 herds were tested, including 23 dairy cattle herds, 43 sheep herds, 9 goat flocks, and 6 mixed flocks (sheep and goats). By ELISA, antibodies against Coxiella burnetii were detected in 30.4% of the BTM tested samples from cattle farms, 60.4% of the sheep farms, and 11.1% of the goat BTM samples. The results were inconclusive in 6.98% of the tested sheep milk samples and 11.1% of the goat milk samples. There was a statistically significant correlation between the herd size and the ELISA S/P % values on the dairy cattle farms. Excretion of the pathogen in milk was detected by PCR in 9 out of 67 BTM samples, including 5 out of 19 cattle BTM samples, 3 out of 39 sheep BTM samples and 1 out of 5 goat BTM ones. The results indicate that C. burnetii infection is widely prevalent in the region, which calls for adequate control and prophylactic measures to reduce the health risks from the transmission of this zoonosis to humans.
Comparative studies on the detection of Theileria annulata infection by clinical, parasitological and molecular techniques in buffaloes (Bubalus bubalis)
Authors:   Department of Veterinary Parasitology, College of Veterinary Science & Animal Husbandry, Kamdhenu University, Junagadh, Gujarat, India, Jamsubhai Thakre Bhupendrakumar , Kumar Binod , Arjanbhai Vagh Arshi , Nayankumar Brahmbhatt Nilima , Chimanbhai Gamit Krishna
Published: February 2024

During the period of 2019-2021, a total of 715 buffaloes were screened for Theileria infections. A set of clinical parameters were used to identify the theileriosis suspected animals which were later confirmed through microscopic tests (peripheral thin blood smear examination and lymph node biopsy smear examination) and molecular assay (cytochrome b based T. annulata specific polymerase chain reaction test). On the basis of clinical evaluation, 33.43% (239/715) buffaloes were suspected for the presence of theileriosis. Through laboratory examination, 63.60% (152/239), 7.48% (16/214) and 100% (239/239) were found positive for Theileria infection by blood smear examination, lymph node biopsy and PCR, respectively, among the clinically suspected theileriosis animals. The efficiency of PCR was recorded to be highest, followed by microscopic examination of peripheral blood smears, and the lowest value was obtained for lymph node biopsy smear examination. The results indicated that PCR is a highly sensitive diagnostic technique for confirmatory diagnosis of T. annulata parasitic infection in buffaloes, even at very low level of parasitemia. Analysis of the data based on thin blood smear examination revealed that the field incidence of theileriosis was 11.55% in the south-western region of Gujarat, India. The high incidences of T. annulata infection in buffaloes may be due to the sub-tropical climate of the region which is favorable for the growth and development of vector ticks and parasites.
Hemangiopericytoma in a senior cat - a case report
Authors:   Department of Veterinary Pathology, Afyon Kocatepe University, Turkey, Fatih Bozkurt Mehmet , Yunus Tüfekci Erkan
Published: February 2024

Even though hemangiopericytoma cases are common in humans and dogs, research so far indicates that they rarely occur in cats. A 13-year-old cat was admitted to an animal hospital with a bleeding mass located close to the caudal mammary glands. No abnormalities were detected in the complete blood count or serum chemistry profile. Following the results of cytology of a fine needle aspiration sample, complete removal of the mass was performed. Hemangiopericytoma was diagnosed by pathological and immunohistochemical analyses of the mass with CD31, vimentin, desmin, SMA, GFAP, SOX-10, S100B and pan-Cytokeratin. Metastasis or recurrence was not observed in the 10-month period after surgery. Compared to previous cases of feline hemangiopericytoma, this is the first cytologically examined tumor located in the mammary gland region, and represents the fourth feline hemangiopericytoma case in the literature.
Long-term supplementation with EPA and DHA changes the fatty acid profile of rat tissues, upregulates NRF2 expression and downregulates TGFβ expression
Authors:   Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia, Starčević Kristina , Roškarić Petra , Percan Valentina , Mašek Tomislav
Published: February 2024

We studied the influence of long-term treatment with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the liver, and kidney lipogenesis, inflammation and antioxidative gene expression. Male Wistar rats were divided into three groups on the basis of the different n6/n3 fatty acid ratios achieved by using different dietary oil blends: the control (CON, n6/n3 ratio was ~7), the N6 group (n6/n3 ratio was ~50) and the DHA group (n6/n3 ~1). Treatment significantly influenced the fatty acid profile of the liver and kidney tissues. The most characteristic changes were an increased content of EPA and DHA in the DHA group in both tissues, of the kidney and liver. The expression of transforming growth factor beta (TGF-ß) was downregulated in the liver tissue by long-term EPA/DHA supplementation. This could be attributed to a decrease in the production of arachidonic acid-derived proinflammatory mediators, and an increase in EPA and DHA derived eicosanoids. DHA and EPA supplementation also significantly increased expression of the NRF 2 gene. This finding suggests that n3 PUFA could influence the activation of the NRF 2 pathway, which is important in cell antioxidative defense. In conclusion, we have shown that long-term dietary supplementation with DHA and EPA could influence lipid metabolism, inflammation and antioxidative defense. Therefore, the long-term addition of dietary DHA and EPA could potentially influence the most important pathological processes in aging.
Endometrial mRNA expression of key inflammatory genes and progesterone receptor in uterine tissue of bitches with endometritis
Authors:   Animal Reproduction Research Institute (INIRA), Faculty of Veterinary Sciences, National University of La Plata, La Plata, Buenos Aires, Argentina, García Mitacek María Carla , Praderio Romina Gisele , Stornelli María Cecilia , De La Sota Rodolfo Luzbel , Stornelli María Alejandra
Published: February 2024

Our study aimed to evaluate the gene transcription of Cyclooxygenase 1 (COX1), cytokines (Interleukin 6 [IL6], Interleukin 8 [IL8], and Leukemia Inhibitory Factor [LIF]), and Progesterone Receptor (PR) in clinically healthy bitches with a normal endometrium and with endometritis, without the presence of cystic endometrial hyperplasia. Forty-eight mixed breed bitches in dioestrus were used. Uterine biopsies were collected for diagnosis of a normal endometrium (n=15), and endometritis (n=30). Three samples were excluded from the study (two bitches with cystic endometrial hyperplasia and one bitch with atrophy). Samples were collected by cytobrush to quantify mRNA by qPCR. Data were analyzed using a generalized mixed model. COX1, IL6, and IL8 mRNA expression in bitches with endometritis was significantly higher than in a normal endometrium (P=0.0002, P=0.002, and P=0.003, respectively). In contrast, LIF and PR mRNA expression in bitches with endometritis was significantly lower than with a normal endometrium (P=0.006 and P=0.001, respectively). IL6 (AUC 0.67) was the most favorable biomolecular marker for predicting endometritis in bitches. There was an evident change in the mRNA expression of COX1, cytokines, and PR in clinically healthy bitches with a normal endometrium and endometritis without cystic endometrial hyperplasia. These results suggest that biomolecular markers such as COX1, IL6, IL8, LIF, and PR could help diagnose endometritis in a bitch.
Investigation of the tumor microenvironment, hypoxia and angiogenesis by immunohistochemical and histopathological methods in canine mammary tumors
Authors:   Izmir Bornova Veterinary Control Institute, Pathology Laboratory, Bornova, Izmir, Turkey, Guner Erdinc , Hatipoglu Fatih
Published: February 2024

The tumor microenvironment (TME) is an important component for studying tumor behavior in several cancers in human beings. However, little information regarding the role of the TME in canine mammary tumors (CMTs) is available compared to humans. In this study, the aim was to investigate the relationship between the TME, hypoxia and angiogenesis through CD31, VEGF, HIF-1a, CD68 and CD163 expression by using immunohistochemical (IHC) methods in formalin-fixed paraffin-embedded canine mammary tumor samples [(n=34: malignant (n=28) and benign (n=6)], to compare them with the clinicopathological features of tumors, and to analyze the relationship between them. There was no significant relationship between CD31, VEGF, HIF-1a, CD68 and CD163 expression in malignant tumors compared to benign tumors (P>0.05). There was an association between microvessel density and clinicopathological variables (the tumor size P=0.013, the presence of necrosis P=0.022) and individual histological grade (G2 vs. G3 P=0.028) in malignant tumors. While there was a positive correlation between CD68 and CD163 in malignant tumors in the dogs (P<0.01), no correlation was determined between other antibodies. Immunohistochemical determination of the level of angiogenesis in the TME may give further useful information about the angiogenic potential and grading of the clinical aggressiveness of some CMTs.
UNA LA CULTURA DE SEGURIDAD INTEGRAL Y SU IMPACTO SOCIAL Y AMBIENTAL EN LA POBLACIÓN MEDIANTE LA EJECUCIÓN DE PROYECTOS DE VINCULACIÓN CON LA SOCIEDAD POR LA TECNOLOGÍA SUPERIOR EN CIENCIAS MILITARES AERONÁUTICAS
Authors: ACUÑA HERRERA MARIA EUGENIA , VIÑACHI BERMEO HERBERT HUMBERTO , YÉPEZ PAZMIÑO ANA MARIA , Barba Cevallos Rosanna Paulina
Published: February 2024

El Proyecto de Vinculación con la Sociedad denominado “Desarrollo de Cultura de Seguridad, en Comunidades Rurales durante el período septiembre 2019 - septiembre 2022”, ejecutado en su parte pertinente entre el 20 de marzo y el 14 de mayo de 2021, por la Tecnología Superior en Ciencia Militares Aeronáuticas, Modalidad Dual del Departamento de Seguridad y Defensa de la Universidad de las Fuerzas Armadas – ESPE, en el sector rural de la Provincia de Cotopaxi, del Cantón Latacunga, de la Parroquia Mulaló en la Comuna San Ramón y el Barrio Ticatilín, en éste los estudiantes de la carrera pusieron en práctica sus conocimientos sobre seguridad integral, permitiendo dar a conocer a la comunidad las responsabilidades sociales en el marco de la salud y cuidado ambiental ante la presencia del COVID-19, logrando que la población objetivo haga suyo el conocimiento. Frente a la incultura de la comunidad sobre seguridad integral, los discentes capacitaron en prevención y enfrentamiento de amenazas a través de la instrucción en medidas de: bioseguridad, defensa y protección del medio ambiente, asistencia y ayuda humanitaria. En el estudio de investigación se utilizó la observación directa, bibliográfica, de campo y un aplicativo para evaluar el impacto en la zona. De los resultados obtenidos se desprende que se mejoró el estilo de vida de los miembros de la comunidad al utilizar las medidas de seguridad integral ante la pandemia de COVID 19 y se fortaleció las relaciones entre los actores civiles y militares, posicionando la imagen institucional.
Reactor calculation automation for the synthesis of a sulfur-containing sorbent intended for heavy metal ions extraction from wastewater
Authors: Aslamova Vera Sergeevna , Aslamov Aleksandr Anatol'evich , Golovkova Elena Aleksandrovna , Shneigelberger Evgeniya Aleksandrovna
Published: February 2024

An automated algorithm for calculating the time of the full cycle of operation, the stages of thermal stabilization and cooling of the reaction mixture in a reactor designed for the synthesis of a sulfur-containing sorbent produced on the basis of waste products from metallurgy, petrochemistry (sulfur), epichlorohydrin (1, 2, 4-trichloropropane) and the pulp and paper industry (lignin) for extraction from wastewater of heavy metal ions. The use of algorithms and a program for automated calculation of the reactor helps to reduce the complexity of production costs and the cost of the finished sorbent, increases the reliability of calculations and the quality of design solutions. The developed algorithms and program include the following calculation routines: physico-chemical properties of the components of the reaction mixture and the choice of a mixing device (propeller three-bladed agitator), taking into account the viscosity of the mixture; hydrodynamic calculation of the mixing device and heat transfer when heating the mixture from 20 to 45 °C; heat transfer during thermal stabilization and cooling of the working mixture, as well as the time of the full cycle of the reactor. The proposed algorithm of heat transfer during thermal stabilization of the reaction mass is based on the determination of the temperature range of water heating, compensating for heat losses. For this purpose, the inverse problem of heat transfer with unknown temperatures over a hot heat carrier is formulated and solved, such that the average value between them is a thermostabilizable value. An algorithm for calculating the cooling process of the reaction mixture in a sulfur-containing sorbent synthesis reactor, taking into account heat losses to the environment in the amount of 5%, is presented. A program has been developed that implements the presented algorithms in C#, designed to automate the calculation of a sulfur-containing sorbent synthesis reactor designed to extract heavy metal ions from wastewater.
Processing and Analysis of the Data Obtained Using Photogrammetry for 3D Scanning
Authors:   Politehnica Timisoara University, Bătrîna Dragoș-Ștefan , Sticlaru Carmen ,   Politehnica Timisoara University
Published: February 2024

Nowadays, 3D scanning can be considered a tool that can be easily used by anyone. There are a lot of 3D scanning methods in which time and money are invested so that they can become more developed, but in the next pages one of the most cost effective to obtain a 3D model, photogrammetry will be described. The method of processing, data gathering (photographs) and an analysis of surface deviation will be presented.
Kinetostatics of a Robotic Prehension Device Driven by Shape Memory Alloy Elements
Authors:   Babeș-Bolyai University, Vela Daniel-Gheorghe , Vela Ion ,   Technical Sciences Academy of Romania, Miclosina Calin-Octavian ,   Babeș-Bolyai University
Published: February 2024

This paper presents the kinetostatic calculus for a robotic prehension device driven by shape memory alloy elements. The constructive-functional scheme is presented, as well as the forces that occur in the prehension process. In order to maintain the workpiece orientation and fixing, the prehension force expression and the relation of the necessary driving force are determined.
Anthropomorphic Robot Factors and Shoppers’ Acceptance of Autonomous Service Robots in Shopping Mall Complexes in Lagos State, Nigeria
Authors:   University of Lagos, Akinbodun Olubukola
Published: February 2024

This study examines the influence of anthropomorphic robot factors on shoppers’ acceptance of autonomous service robots in shopping mall complexes. It also contributes to the Service Robot Acceptance Model from the context of a developing country by validating three robot factors such as appearance, social capability and usefulness from shoppers’ perspectives.
Adaptive-PID Experimental STM32F4 Controller for Rotary Inverted Pendulum
Authors:   Bosch Global Software Technologies, Ho Chi Minh city University of Technology and Education, Pham Le-Anh-Dung , Tran Vu-Quan ,   Ho Chi Minh city University of Technology and Education, Nguyen Thanh-Tay ,   Ho Chi Minh city University of Technology and Education, Le Minh-Huy ,   Ho Chi Minh city University of Technology and Education, Nguyen Viet-Duc ,   Ho Chi Minh city University of Technology and Education, Le Van-Hiep ,   Ho Chi Minh city University of Technology and Education, Pham Thanh-Thai ,   Ho Chi Minh city University of Technology and Education, Trinh Tan-Dai ,   Ho Chi Minh city University of Technology and Education
Published: February 2024

Rotary inverted pendulum (RIP) is a classical model of control engineering. Paper deals with a PID-adaptive structure which is based on structure of neuron to train Kp, Ki, Kd through operation. In simulation, our adaptive controller is proven to work in larger range than classical PID controller. Through experimental model using STM32F4, we prove vibration of system under adaptive-PID is smaller than under classical PID structure. Then, combination of neuron network (NN) and PID control can be used as simple structure for single-input multi output (SIMO) systems which are similar to RIP.
The Self-Efficacy Perception for Environmental Education and Ecological Footprint Awareness of the Child Development Programme Students
Authors: Pullu Emine Kübra , GÖmleksiz Mehmet Nuri
Published: February 2024

The purpose of this study was to examine the correlation between the self-efficacy perception for environmental education and ecological footprint awareness of the child development programme students. Sample group of the study which was carried out according to the correlational survey model was specified according to convenience sampling. The sample group consisted of students studying in child development departments in four universities in Turkey. In the study, “Self-Efficacy Scale for Environmental Education” and “Ecological Footprint Awareness Scale” were used as data collection tools. For the data analysis, the Kolmogorov-Smirnov, t, variance tests and The Spearman’s correlation coefficient was used. In the research results, it was revealed that the environmental education self-efficacy perception and ecological footprint awareness levels of the students of the child development programme positively affect each other at a moderate level.
Serotonin Immunoreactive Cells in Extrahepatic Bile Ducts, Major Duodenal Papilla and Gallbladder in the Domestic Pig
Authors: Stefanov Ivaylo
Published: February 2024

The main part of serotonin in the body is synthesized and released by a certain type of enteroendocrine cells in the intestinal mucosa called enterochromaffin cells. The scarce qualitative and quantitative data on enterochromaffin and serotonin-positive mast cells in porcine extrahepatic bile ducts and gallbladder, motivated us to undertake the present study. The aim of this study was to determine the localization and density of serotonin-positive cells in the wall of the extrahepatic bile ducts and gallbladder in pigs. An immunohistochemical method was used to identify enterochromaffin cells and determine their percentage relative to the total number of endocrine cells labeled with chromogranin A. Serotonin-positive mast cells were identified after tryptase staining of serial sections. The endocrine function of mast cells was demonstrated by chromogranin A immunolabeling. The highest number of enterochromaffin cells were found in the intramural part of the ductus choledochus, followed by the papilla duodeni major, extramural part of the ductus choledochus, ductus hepaticus comunis, ductus cysticus, and gallbladder. In all parts of the extrahepatic bile ducts, the highest number of mast cells was found in the muscle layer, followed by the serosal layer and the propria. The expression of serotonin in the enterochromaffin cells of the biliary glands and in the mast cells of the analyzed organs suggests a possible synthesis of serotonin, which probably regulates physiological and pathological processes.
Importance of natural conditions in Poland in the operation of fully organic farms and those with co-existing conventional production
Authors: Zieliński Marek , Gołębiewska Barbara , Adamski Marcin , Sobierajewska Jolanta
Published: February 2024

This study addresses the issue of assessing the functioning of farms in areas with diverse natural farming conditions by evaluating them using the latest version of the Agricultural Production Area Valorization (APAV) index. Analyses were performed on three types of farms: fully organic farms, organic farms with co-existing conventional production, and conventional-production farms. To achieve the research objective, 259 communes were selected depending on the level of their APAV. Assessments were made of their production potential, production organization, production and economic results in communes with average APAVs below, equal to, and higher than the national average (66.6 points) based on data from farms continuously keeping accounts for the Polish farm accountancy data network (FADN) in between 2019–2021. The Shannon-Wiener index (S-W index) was used to measure the degree of diversity of crop species in the farms’ sown crops, and determine what proportion of those were structure-forming plants. This research demonstrates that in order for interest in organic production to develop under current conditions, there must be sufficient financial support for agricultural producers, especially in areas with more difficult farming conditions.
Sensitivity of the global agricultural sector to changes in climate policy - EU countries compared to the rest of the world
Authors: Wąs Adam , Sulewski Piotr , Kobus Paweł , Pietrzykowski Robert , Jeszke Robert , Pyrka Maciej
Published: February 2024

There has been a decline in greenhouse gas (GHG) emissions per capita in all world regions since the 1990s. In developing countries, this decline has been attributed to population growth and an increase in absolute emissions, while in developed countries, the trend is mainly due to a decrease in absolute emissions combined with minor population changes.

This paper aims to delve into the intricacies of global GHG emissions, with a spotlight on the agricultural sector. This paper assesses the patterns and reasons behind the decline in GHG emissions per capita since the 1990s across different regions. In particular, it addresses the concept of the “sustainable intensification of agriculture” and the debate between intensive vs. less-intensive production in the context of GHG emissions. Despite having high emissions per hectare, we argue that European countries show lower emissions in relation to production value, highlighting the region’s production intensity and efficiency. Compelling visual data representations and references from significant international bodies, such as the IPCC and EEA, bolster the paper’s findings and conclusions.
OPTIMIZACIJA PROIZVODNIH PROCESA PRIMENOM SIMULACIJA U KOMPANIJI BIOELEMENTS D.O.O
Authors: Tot Tamaš , Bojić Sanja Pavao
Published: February 2024

Tema ovog rada je izrada simulacionog modela, analiza i optimizacija tokova materijala proizvodnog sistema u kompaniji Bioelements d.o.o., pri čemu je fokus usmeren na procese sečenja metala na laseru, pripreme i odlaganja materijala i zavarivanja sklopova određenih mašina u cilju smanjenja zaliha. Ovi procesi se izvode na 4 vrste mašina prema broju porudžbina od strane kupca. Simulacija je rađena u softveru Tecnomatix Plant Simulation koji nudi razne mogućnosti za optimizaciju proizvodnih i logističkih sistema u 2 i 3 dimenzije.
СТАТИЧКО ИСПИТИВАЊЕ И ВЕРИФИКАЦИЈА ПРИМЕНОМ МКЕ СТАЗЕ МОДЕЛА МОСНЕ ДИЗАЛИЦЕ
Authors: Јошић Дарио , Иланковић Никола
Published: February 2024

Овај рад приказује поступак инжењерске анализе датог проблема која се састоји од теоријске и експерименталне анализе. Предмет разматрања је понашање конструкције стазе модела мосне дизалице. Урађена су испитивања у виду мерења напона под одређеним условима и резултати истих су упоређени са претходно добијеним резултатима из софтвера.
PREDIKTIVNO MODELOVANJE HRAPAVOSTI POVRŠINE PRI OBRADI GLODANJEM LEGURE TITANIJUMA Ti-6Al-4V UZ UPOTREBU MAŠINSKOG UČENJA
Authors: Đurić Mile , Savković Borislav
Published: February 2024

Analiziranje uticaja ulaznih faktora na izlaznu veličinu (hrapavost), modelovanje optimalne kombinacije faktora u cilju postizanja bolje hrapavosti obrađene površine.
POREĐENJE UTICAJA OD VERTIKALNOG SAOBRAĆAJNOG OPTEREĆENJA NA ARNIRANO-BETONSKOM PREDNAPREGNUTOM MOSTU NA 2 POLJA
Authors: Aleksandrić Lazar , Rašeta Andrija
Published: February 2024

U ovom radu su upoređeni rezultati dobijeni od vertikalnog opterećenja na armirano-betonskom mostu korišćenjem evropskih normi EN 1991-2 i korišćenjem srpskog Pravilnika o tehničkim normativima za određivanje veličine opterećenja drumskih mostova iz 1991. godine.
КУЛТУРА БЕЗБЕДНОСТИ САОБРАЋАЈА
Authors: Чутурић Дарко
Published: February 2024

Култура безбедности саобраћаја је релативно нов концепт који у последње време добија пажњу у области безбедности саобраћаја. Култура безбедности саобраћаја чини се као интуитиван и моћан концепт којим се објашњавају посматране разлике у међународним, регионалним и демографским ризицима од незгода, као и склоност ка високоризичном понашању.
АНАЛИЗА БЕЗБЕДНОСТИ САОБРАЋАЈА У ПРОЦЕСУ РАЗВОЈА ПРОЈЕКТА
Authors: Лукић Марина
Published: February 2024

Анализа безбедности на путевима је важан део у пројектовању путева. Основни циљ јесте избор ефикасних решења безбедности саобра­ћаја међу више алтернатива пројекта пута.
ANALIZA I KONTROLA KVALITETA REDUKCIJE ŠUMA NA DIGITALNIM FOTOGRAFIJAMA
Authors: Babić Tamara , Jurič Ivana
Published: February 2024

U radu je kroz teorijske osnove opisan šum, vrste šuma i postupci za njegovo uklanjanje, kao i kontrola kvaliteta fotografije. U praktičnom delu se vršila korekcija na primerima fotografija u JPG i RAW formatu i prikazani su rezultati istraživanja kontrole kvaliteta upotrebom SSIM metrike.
BEZBIJEDNOST I ZDRAVLJE NA RADU U PROCESIMA ZAVARIVANJA
Authors: Despotović Paulina , Adamović Dragan Ljubomir
Published: February 2024

Zavarivanje je osnovni proizvodni proces koji se koristi u postupcima spajanja materijala u različitim industrijama. Poznavanje različitih tehnologija zavarivanja, od elektrolučnog do laserskog zavarivanja, omogućava izbor najpogodnije tehnike. Procesi zavarivanja mogu doprineti zagađenju vazduha kroz emisiju praškastih materija, uključujući suspendovane čestice iz kategorija PM10 i PM2.5. Primjenom efikasnih ventilacionih sistema, kontrola izduvnih gasova i mehanizama za filtriranje, oslobađanje ovih praškastih supstanci se može svesti na minimum. U radu je istaknuta važnost upotrebe lične zaštitne opreme (LZO) kao ključne zaštite u okruženju zavarivača. Pravilan izbor i upotreba LZO može da umanji rizike povezane sa procesima zavarivanja i doprineti opštem blagostanju radnika.
Proceedings of the Pirogov Surgical Societies № 2575–2578
Authors: Editorial Article
Published: February 2024

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A atualidade dos clássicos da Novos Estudos Cebrap
Authors:   Equipe editorial
Published: February 2024

Nestes mais de 40 anos desde a publicação do primeiro número da Novos Estudos Cebrap, em dezembro de 1981, seus artigos foram lidos, relidos, citados e comentados por pesquisadores, estudantes e pessoas interessadas em ciências humanas no Brasil e em outras partes do mundo. Esses textos integraram ementas de disciplinas universitárias e pautaram a mídia, tornando-se objetos de debate dentro e fora da academia. Foi assim que, com espírito democrático e interdisciplinar, a revista influenciou e ajudou a consolidar diversas áreas das ciências humanas no Brasil. Agora, olhando para essa trajetória, podemos dizer que esses artigos se tornaram clássicos por participarem de maneira determinante na comunicação e na divulgação científica. Por esse motivo, eles não são clássicos apenas da revista, mas de suas áreas disciplinares e do grande público. São textos que repercutiram entre as leitoras e os leitores da revista e ainda continuam a fazê-lo, seja como parte de suas formações ou como fontes para pesquisas mais recentes. Os clássicos têm dimensão universal, atravessam gerações, fronteiras e nacionalidades, sem perder suas características. São textos que nunca envelhecem e sempre tem algo a dizer. A seção “A atualidade dos clássicos da Novos Estudos Cebrap” aparece pela primeira vez neste número com a proposta de registrar o debate com esse passado que se mostra vivo no presente e aponta para o futuro. Na tentativa de celebrar e promover o diálogo, serão apresentados nessa seção comentários que indicam mudanças, novidades e a atualidade de problemas e interpretações anunciadas a princípio em artigos publicados nestes 40 e poucos anos de história. A equipe editorial.