bluuebunny/crossref_metadata_2025 huggingface dataset:
Desafíos éticos para la investigación en Latinoamérica
Authors: Toro Edgardo , Duque Deyanira , Rincón Magda L. , Guerra Cristobal , Olivares Fernanda , Valenzuela Magdalena , Reid Corinne , Calia Clara
Published: January 2024

El propósito del estudio fue identificar los desafíos éticos que enfrentan los investigadores en Latinoamérica. Metodología: se planteó un estudio cualitativo en el que participaron 31 investigadores latinoamericanos, representantes de 6 países. En la primera fase, se realizó una encuesta en línea con pregunta abierta diligenciada por los 31 investigadores; en la segunda fase, una entrevista semiestructurada en donde participaron 23 de estos investigadores. Desarrollo: se identificaron 6 desafíos para la ética de la investigación: i) desde y hacia una Latinoamérica global, ii) hacia una cultura de investigación ética, iii) la ética dentro y fuera de la investigación, iv) relaciones humanas en investigación, v) presencia/ausencia de los comités de ética, vi) COVID-19, un nuevo escenario. Entre los aspectos más relevantes planteados por los participantes,se encuentran la generación de investigaciones sensibles a la variabilidad cultural que impactan positivamente las problemáticas locales, la necesidad de gestar alianzas sur-sur que definan políticas públicas en el tema, la reorientación de políticas latinoamericanas centradas en la región, el impulso a la formación en ética de la investigación desde inicios de la formación, la apertura de discusiones sobre el tema en la región para el desarrollo de directrices y una mayor conciencia en este tópico, la reflexión sobre el papel de los comités de ética como asesores y educadores, la flexibilidad en el consentimiento informado adaptable a las diversas condiciones y contextos, además de retos específicos derivados de la situación de pandemia por COVID-19.
The Effectiveness of Therapy Based on Acceptance and Commitment regarding Reducing Hopelessness and Anxiety of Working Children in Yazd city
Authors: Mahdvar Elahe , Choobforoushzadeh Azadeh , Mohammad panah Azra , Shirovi Elahe
Published: January 2024

Introduction: The phenomenon of working and street children is one of the problems that plagues most big cities. Working children means children and teenagers who, according to social laws, under the age of 18 engage in activities to earn money. The purpose of this research is to investigate the effectiveness of treatment based on acceptance and commitment regarding reducing hopelessness and anxiety of working children in Yazd City.
Method: The method of the current research was semi-experimental, and its design was pre-test-post-test with a control group and a four-week follow-up. The statistical population included working children in the age group of 8 to 12 who were covered by the welfare management of Yazd city in the spring of 2019. The study sample included 30 working children who were placed randomly in 2 control and experimental groups using convenience sampling. Data collection tools included Kazdin's Children’s Hopelessness Scale and Spence's Children’s Anxiety Scale. The experimental group received 8 one and half an hour sessions of treatment based on commitment and acceptance, but the control group was placed on the waiting list. Data analysis was done using analysis of covariance test and SPSS software.
Results: The results of the present study, according to the analysis of covariance, showed that the treatment based on acceptance and commitment significantly reduced the level of frustration and anxiety in working children (p<0/05).
Conclusion: Based on the findings, it can be concluded that the treatment based on commitment and acceptance has been able to reduce hopelessness and anxiety of working children. It is suggested to organize psychological interventions and trainings with the help of relevant organizations in order to improve working children’s mental health and reduce their anxiety and frustration.
Investigating the Factors Related to the Reduction of Salt Consumption in Women in Southern Iran: Application of ،ranstheoretical Model
Authors: Pourjalil Farzaneh , Homayuni Atefeh
Published: January 2024

Introduction: Reducing salt consumption in population is one of the easiest, most efficient and cost-effective ways to reduce the burden of cardiovascular diseases. The present study was conducted with the aim of investigating the factors related to the reduction of salt consumption using transtheoretical model among women in southern Iran.
Methods: This was a cross-sectional study (descriptive-analytical) conducted from November 2022 to February 2023 on women of 18-59 who visited comprehensive health centers in Bastak city. A total number of 452 subjects were selected using convenient sampling method. Data were collected using a questionnaire   with three sections: demographic information, a researcher-made questionnaire based on transtheoretical model constructs, and salt consumption reduction questionnaire. Data were analyzed using Kruskal-Wallis tests, Pearson's correlation and regression analysis with SPSS software (v. 22).
Results: The results showed that participants were between 18 and52 with a mean of 35/51±10/13. 23/5% of the participants were in pre-contemplation stage, 21/7% in the contemplation stage, 20/8% in preparation stage, 11/3% in action stage, and 22/8% in maintenance stage.  Pearson correlation analysis results indicated that there were significant positive relationships between cognitive processes (r= 0/44, p<0/01), behavioral processes (r= 0/54, p<0/01), self-efficacy (r=0/43, p<0/01) , decision balance (r= 0/37, p<0/01), and salt consumption reduction behavior; but, there was a significant negative correlation between temptation and salt consumption reduction behavior (r=-0.34, p<0/01). Moreover, regression analysis results revealed that age, counter conditioning, self-efficacy, raising awareness, decision balance, helping relationships, and temptation can predict 38/1% of the total variance in salt consumption reduction behavior (p<0/05).
Conclusion: According to the findings, self-efficacy, temptation, cognitive and behavioral change processes, and advantages and disadvantages of salt reduction play a major role in salt consumption reduction behavior. It is suggested that these variables be taken into account in developing and implementing educational interventions.
CONSTRUINDO O ESTADO E TECENDO O LUGAR DOS PODERES
Authors: Antônio Edna Maria Matos
Published: January 2024

O artigo analisa as demandas originadas nos órgãos de representação provincial no pós-Independência encaminhadas para a Assembleia Legislativa do Império com o fim de fornecer elementos para a análise da relação entre o centro de poder e as províncias no Primeiro Reinado. Aborda a importância da questão regional no processo de luta política que levou a América portuguesa a se separar de Portugal (1820-1823) e os anseios relacionados à construção de instâncias e rotinas que permitissem o exercício do poder regional em algum nível ou intensidade. Essa reflexão, com apoio bibliográfico especializado, analisa a experiência da província de Sergipe, sua trajetória e demandas interpostas a análise da Assembleia Legislativa do Império. A tensão entre expectativas de centralização e descentralização e a observância de assuntos de interesse absolutamente locais e outros de envergadura nacional põem em evidência que o arranjo encontrado se situou a meio termo das aspirações elaboradas no início dos debates que levaram à Independência, mostrando que muitas decisões importantes para a localidade continuavam dependentes de decisão de instância superior e poder em formato centralizado.
POLÍTICA INDÍGENA, INDEPENDÊNCIA DO BRASIL E A CÂMARA MUNICIPAL DA VILA DE ÍNDIOS DE ARRONCHES – CEARÁ
Authors: Costa João Paulo Peixoto
Published: January 2024

O processo de independência política do Brasil contou com uma heterogênea participação população, com sua diversidade de experiências, culturas políticas, projetos de futuro e formas de atuação. Nas povoações sujeitas ao Diretório dos Índios com categoria administrativa de vila havia câmaras municipais, onde as lideranças indígenas tinham prioridade na ocupação de cargos de vereação. O presente artigo se dedica a refletir sobre o caso da câmara municipal da vila de índios de Arronches. Analisaremos fontes que se remetem ou que foram produzidas no senado, e a mais importante delas para este estudo é um livro presente na Biblioteca Nacional (1793-1831). Tentaremos identificar o papel que a câmara dessa uma vila de índios assumiu no processo de independência e como pôde ser um ambiente possível de exposição das demandas da comunidade indígena que representava.
PARA ALÉM DO 22
Authors: Santos Edyene Moraes dos , Araújo Johny Santana de , Araújo Roni César Andrade de
Published: January 2024

A chamada para este dossiê teve como objetivo fomentar o debate acerca do processo de formação do Estado Imperial do Brasil, que não se encerra em 1822, mas que pode ser analisado a partir das especificidades das Províncias do Norte, envolvendo pesquisadores, docentes e discentes interessados nessa temática, como forma de incentivar investigações e colaborações acadêmicas no Maranhão e em outras regiões do Brasil e do exterior.
BATALHAS IMPRESSAS
Authors: Abrantes Elizabeth Sousa , Mateus Yuri Givago Alhadef Sampaio
Published: January 2024

A Independência do Brasil no Maranhão foi marcada por singularidades, entre as quais uma guerra civil provocada pela demora em aderir à nova ordem política instituída com a separação política da metrópole, capitaneada pelas províncias do Sul do país. A guerra, no entanto, não ocorreu apenas nos campos de batalha do sertão maranhense, mas foi combatida também por meio das narrativas da imprensa oficial da província, por meio do jornal O Conciliador do Maranhão. Este estudo tem por objetivo analisar os discursos veiculados na imprensa local em prol da união com Portugal no contexto das lutas pela Independência no Maranhão, abordando as representações sobre as forças expedicionárias formadas pelos independentistas e os embates em torno da formação de uma opinião pública contrária à incorporação da província do Maranhão ao nascente império brasileiro.
El camino de Damasco del converso Francisco de Acevedo: De Galicia al Perú (1591-1604)
Authors: Tardieu Jean-Pierre
Published: January 2024

Un joven converso gallego, iniciado en la fe de Moisés por las mujeres de su familia cerca de la frontera portuguesa, poco antes de trasladarse al Perú a ﬁnes del siglo XVI, solicitó, en 1603, la absolución del Santo Oficio de Lima, obsesionado por la salvación de su alma y sus experiencias místicas. Manejando su estado de ánimo neurótico, los inquisidores intentaron sacar todo el provecho de un caso de poca relevancia para darse los medios de acabar con un núcleo criptojudaizante que se había extendido hasta las Indias.
Mediasi Kinerja Keuangan pada Hubungan Leverage dan Likuiditas terhadap Penghindaran Pajak
Authors: Mardiana Mardiana , Setiyowati Supami Wahyu
Published: January 2024

Purpose: Tax avoidance is a strategic approach aimed at reducing the tax burden while staying within the boundaries of applicable regulations. The objective of this study was to examine how leverage and liquidity influence tax avoidance, with financial performance acting as an intermediary factor.

Method: The research focused on publicly listed financial sector companies on the Indonesia Stock Exchange (IDX) from 2019 to 2022. The sample selection process adhered to specific criteria, resulting in a sample size of 38 companies. Smart PLS was employed as the data analysis technique.

Results: The findings indicated that leverage had an impact on financial performance, liquidity affected financial performance, and financial performance played a role in tax avoidance. However, financial performance did not act as a mediator in the relationship between leverage, liquidity, and tax avoidance.

Implications: This research can be used as material for study and evaluation for the government in relation to existing tax policies. On the other hand, it is expected to increase compliance and awareness of the company in fulfilling its tax obligations.

Novelty: This research uses profitability mediation in the relationship between leverage, liquidity, and tax avoidance
Dramaturgy Study: The Story of “Si Pandir” on The Effectiveness of Village Fund Management
Authors: Cahyono Suham , Sudaryati Erina , Sawarjuwono Tjiptohadi
Published: January 2024

Purpose: The aim of this study was to uncover the intricacies of village fund budget management by offering a comprehensive portrayal of the behaviors exhibited by the key actors involved in village budget management, both in front and behind the scenes. The aim of this study focuses on the workings of the X village fund budget, highlighting the role of third parties in optimizing the utilization of the X village fund budget.

Method: A qualitative method with a dramaturgical study approach is used in this study to answer the proposed study proposition

Results: The findings indicate that the dynamics observed in the management of the X village fund budget can lead to optimal resource allocation aligned with the village's development objectives and the well-being of its community. This is because the village fund administrators engage in strategic budgetary maneuvers to achieve the utmost efficiency in budget management. The positive impact stemming from the proactive involvement of the village apparatus, colloquially referred to as "Si Pandir," is the promotion of equitable development and the enhancement of village welfare. Through collaboration with relevant government entities, the village apparatus can facilitate the provision of advanced and fair amenities for the village, fostering cooperation that benefits the entire community.

Implications: The results of this study can be used for future research to develop an optimal village fund management concept, not only from the perspective of the related village apparatus but also involving the active participation of the local community.

Novelty: This research elaborates on village fund management with the Pandir legend as the most popular folklore in Java.
Analisis Determinan Pencegahan Fraud Pengelolaan Dana Desa dengan Moralitas sebagai Moderasi
Authors: Putri Hanah Ladhinah , Yuliani Nur Laila , Mranani Muji , Anisa Friztina
Published: January 2024

Purpose: This study aims to test empirically and analyze the effect of competence, internal control systems, religiosity, and whistleblowing on fraud prevention in managing village funds with morality as a moderating variable.

Method: The research sample was village officials in Secang District, Magelang Regency using the purposive sampling method and obtained 78 respondents, while for testing the hypothesis using moderated regression analysis.

Results: The results showed that competence had a positive effect on fraud prevention in managing village funds and religiosity had a negative effect on fraud prevention in managing village funds. Meanwhile, the internal control system and whistleblowing have no effect on fraud prevention in managing village funds. Morality strengthens the influence of religiosity on fraud prevention while morality weakens the influence of competence on fraud prevention in village fund management. However, morality does not moderate the influence of internal control system variables and whistleblowing on the prevention of village fund management fraud.

Implications: This research is expected to add to knowledge, insight, and empirical evidence and can be a reference for further research on fraud prevention in village fund management. In addition, it is hoped that this will provide additional information and input to encourage the Village Government to improve fraud prevention in managing village funds

Novelty: This research builds on previous research by adding a whistleblowing variable which is expected to improve performance and prevent fraud.
Revealing Islamic Cultural Values behind Capital Accounting Practices: A Study of Islamic Ethnomethodology
Authors: Thalib Mohamad Anwar
Published: January 2024

Purpose: This study aims to reveal the values of local wisdom behind the practice of capital accounting.

Method: This study uses an Islamic paradigm with an Islamic ethnomethodology approach.

Results: The results showed that the source of capital from the coachmen to buy the transportation of the hansom and horses were the gifts of their parents and other businesses. The capital is conditional on the value of responsibility to finance family needs and the value of patience for an undetermined amount of income. These two values reflect the parents' expressions in the form of delo sipati lo malu'o, tiloliyo kulu-kulu walaiyo modudu'o. It means to express feelings of family responsibility, and mopo'o tanggalo duhelo means full of patience.

Implications: The results of this study seek to preserve accounting based on local culture.

Novelty: The results of this study contribute to the presence of the concept of capital accounting practices based on Islamic cultural values in the Gorontalo community.
Corporate Spiritual Responsibility (CSpR): Kontruksi Model CSR berdasarkan Surat Al-Mudassir dan Kitab Tarbiyah Wa Tahdzib
Authors: Jannah Fitriyahtul , Leniwati Driana
Published: January 2024

Purpose: This study aims to construct the model of Corporate Social Responsibility (CSR) based on Surah Al Mudassir and Kitab Tarbiyah Wa Tahdzib in Islamic boarding schools.

Method: This research uses a postmodernist-interpretivist paradigm where the research tries to integrate the meaning of each data obtained through interviews and construct a Corporate Social Responsibility (CSR) model based on Surah Al Mudassir and the Kitab of Tarbiyah Wa Tahdzib.

Results: Empirically in Islamic boarding schools, it was found that 1) The application of Corporate Social Responsibility (CSR) towards profits is interpreted as sustenance that arises from a sense of sufficiency and gratitude, 2) The application of Corporate Social Responsibility (CSR) towards people is interpreted as charity service. 3) The implementation of corporate social responsibility (CSR) for the planet is interpreted as mutual concern and responsibility.

Implications: this study provides implications for accounting science, especially the concept of CSR in a broader context

Novelty: This study focuses on the construction of a CSR model that integrates organizational culture, religion and spirituality into a CSR model based on Surah Al Mudassir and Kitab Tarbiyah Wa Tahdzib
Sanksi Terhadap Pelaku Kekerasan Pada Anak Yang Mengakibatkan Luka Berat
Authors: Anggraini Meli Dwi , Zailia Siti , Armasito Armasito
Published: January 2024

Recently there has been frequent violence against children which of course violates children's rights. Various types of violations against violence against children seem to assume that children do not have rights to be protected. The main problem of this research is how to study Islamic law and positive law against sanctions on juvenile crimes that result in serious injuries in Decision Number: 1961/Pid.Sus/2016/PN .Plg. The purpose of this research is to examine the sanctions for perpetrators of crimes against children both in terms of Islamic law and positive law. The type of research used is literature (library research) which is analyzed using descriptive analysis techniques. The approach method is comparative, namely comparing Islamic law and positive law regarding sanctions for perpetrators of child crimes. The results of this study reveal that the judge's considerations in convicting criminals against perpetrators of violence against children who cause serious injuries in Decision Number: 1961/Pid.Sus/2016/PN .Plg. That is, the judge has first considered the facts at trial. In Islamic criminal law, criminal acts are punished with ta'zir, that is, in accordance with the actions and the decision is left to the ruler's policy or law. The difference between the two laws is that the witness imposed on the perpetrators of abuse according to law number 13 of 2014 is in the form of imprisonment, whereas in Islamic law it is in the form of qishas, diyat and ta'zir punishments.
Kedudukan Laporan Akhir Hasil Pemeriksaan (LAHP) Ombudsman Ditinjau Dari Fiqih Siyasah dan Undang-Undang
Authors: Thohari Imam
Published: January 2024

Maladministration cases that often occur can harm a number of people. Therefore, it is necessary to have an agency that specifically accepts reports on these matters, namely the Ombudsman of the Republic of Indonesia. In the process, the report will be concluded in the Final Examination Results Report (LAHP) regarding whether or not the case is proven. This study aims to examine the position of the Final Examination Report Report (LAHP) in the Siyasah Fiqh and Law Number 37 of 2008 concerning the Ombudsman of the Republic of Indonesia. The formulation of the problem is how is the Position of the Ombudsman Final Examination Report (LAHP) in terms of Fiqh Siyasah and Law Number 37 of 2008 concerning the Ombudsman of the Republic of Indonesia? The type of research used in this study is empirical. While the approach used in this study is the Sociological Legal Approach (Sociological Juridical). This research was conducted through interviews and study of documents, files and annual reports as well as books and other related documents. The research location is the Ombudsman Representative of South Sumatra. The results of the study concluded that first, in terms of the Fiqh Siyasah Ombudsman, it is included in the Wilayatul Hisbah which is obliged to uphold 'Amr Ma'ruf Nahi Munkar among public service providers. Second, the position of the LAHP in review based on the law has been recognized by the state and must be carried out by the reported party or the reported superior based on the hierarchy of laws in force in Indonesia.
Hukum Perempuan Sholat Berjamaah di Masjid
Authors: Cholidi Cholidi , Zuraidah Zuraidah
Published: January 2024

Congregational prayers in Islam have added value. Likewise praying in the mosque has additional appreciation from Allah Subhanahu wa Ta'ala. Especially if the prayers are performed in congregation and carried out in the mosque. But in daily reality there are those who judge that congregational prayers performed at the mosque by women are not a good deed. Therefore, this article discusses the issue of how the law holds congregational prayers for women in mosques according to the perspective of madhhab scholars. The purpose of this study was to examine the legal basis for congregational prayers at the mosque for women based on the opinion of the Islamic scholars. This research is a literature research by examining the treasures of the book referred to by the school's scholars. From searching this article, it was found that the opinion of madhhab scholars absolutely prohibits (forbids) women from participating in congregational prayers at the mosque.
Penerapan Sanksi Pencurian Terhadap Penderita Kleptomania Menurut Hukum Positif dan Hukum Pidana Islam
Authors: Fikri Ikhwan , Fathimah Ema , Tiara Bunga Putri
Published: January 2024

One of the cases that needs to be anticipated and followed up in criminal cases is theft, which often disturbs the public. An example is the case of a criminal act of theft committed by a kleptomania sufferer by a housewife who lives in Kupang City in 2017. This research discusses the analysis of jinayah fiqh or Islamic criminal law and positive law on the application of criminal sanctions for theft based on KUPANG District Court Decision Number 32/Pid.B/2018/PN Kpg. The research method used by researchers is a normative research method which is carried out by examining laws and regulations that are directly related to the crime of theft. The results of the research that have been studied by researchers are that according to article 44 paragraph of the Criminal Code concerning the responsibility of perpetrators of criminal acts of theft who experience mental disabilities such as sufferers of kleptomania, the judge has the authority to decide on an order and send the perpetrator of the crime to a mental hospital for the longest possible time. one year, while the crime of theft by a person suffering from kleptomania according to Islamic law is not subject to a had sentence but rather a ta'zir punishment as ta'dib or teaching in the form of a rehabilitation sentence and a fine which is accountable to the victim.
Pemanfaatan Sawah Warisan Secara Bergilir Menurut Hukum Islam dan Hukum Adat
Authors: Endry Endry , Torik Muhammad , Purnomo Bitoh
Published: January 2024

The use of inherited rice fields in rotation is in accordance with customary inheritance law and article 189 KHI, namely using collective principles. This is not in accordance with the individual principle in Islamic inheritance law. One reason is that in the collective system there is a delay in the distribution of inherited assets. This has the potential to cause conflict. The formulation of the problem in this research is how to implement the use of heritage rice fields in rotation among the Mayapati Village community. The aim of the research is to examine through Islamic law and customary law the rotational use of inherited rice fields in the Mayapati Village community. The type of research is field research with data collection through interviews, observation and documentation. This research is also normative legal research with a qualitative approach, namely data obtained through library materials such as books, documents or statutory regulations related to the problems that occur. Descriptive in nature, that is, the problem is formulated according to the facts that occurred. According to customary law, inherited rice fields are used in rotation according to a collective system. According to the view of Islamic law, inheritance should be divided based on the parts regulated in the text. Referring to the Compilation of Islamic Law, the rotational use of inherited rice fields which is in accordance with Islamic Law is only inherited collectively, in accordance with property rights in Islamic law, namely ownership for the benefit only or haqqul intifa', while the rotational use of rice fields is not in accordance with work regulations. with muzara'ah.
Lei de cotas e assistência estudantil no Instituto Federal do Acre: análise das taxas de permanência e êxito nos cursos do ensino médio integrado (Campus Rio Branco)
Authors: Barbosa Lorena Rodrigues , Lobregat Maria Cristina , Lobão Mario Sérgio Pedroza
Published: January 2024

The article analyzes the retention and success rates of students entering in 2019 in Integrated High School courses at the Federal Institute of Acre (Campus Rio Branco), benefiting from student assistance notices (socioeconomic support programs) during the period of curricular completion and, furthermore, observes existing policies, their applicability and effects regarding the retention and success of incoming students in the form of quota places and broad competition. The methodology used was of a qualitative-quantitative approach and applied in nature. As for procedures, it is considered documentary and bibliographic. Based on concepts from the Nilo Peçanha Platform, data collected from the School Registration Coordination and the Student Assistance Center both at the Rio Branco Campus were discussed, obtaining retention and success rates and reflecting on the effects of the assistance policy student. Based on research carried out in Federal Institutes on the topic of permanence and success in technical courses. In view of the research carried out, the results demonstrated, in many situations, that the ideal of democratizing the entry of vulnerable popular classes is not a guarantee of success in professional training and that there is a need to think about the development of institutional actions for the strategic plan of permanence and success.
“Isso não vai tirar a feminilidade dela de forma alguma”
Authors: Lima George Almeida , Martins Daiane Grillo , Silva Fábio Júlio Serafim da , Mariante Neto Flávio Py , Vasques Daniel Giordani
Published: January 2024

Objetivo: Este estudo objetivou analisar a percepção das mulheres sobre sua participação nas aulas de capoeira no município de Campos Sales/CE. Metodologia: Este estudo, de caráter qualitativo e exploratório, utilizou-se da entrevista semiestruturada enquanto recurso para coleta de dados. Participaram deste estudo, três mulheres, duas de 17 e uma de 18 anos, praticantes de capoeira em Campos Sales/CE. Resultados e discussão: a prática da capoeira em Campos Sales/CE possui singularidades que dificultam a inserção e permanência das mulheres, como: consolidação da masculinidade hegemômica, ausência de locais específicos, troca constante de professores, despesas inerentes às graduações e ausência de equipamentos. Considerações Finais: a inserção das mulheres na capoeira desencadeia maiores esforços para que possam inserir-se e manterem-se na capoeira, pois além de fatores estruturais, precisam negociar sua participação a partir da legitimação de posturas agressivas, buscando lutar “de igual para igual” com os(as) demais participantes.
Rosae multiflorae fructus regulates the lipogenesis in high-fat diet-induced NAFLD mice model
Authors: Kim Kibong , Jang Hyun Joo , Baek Suji , Ahn Sang-hyun
Published: January 2024

[Purpose] Exercise helps modify the lipid profile in the body, partly through its impact on sterol regulatory element binding protein-1 (SREBP-1) and peroxisome proliferator-activated receptor-γ (PPAR-γ). Individual differences in response to exercise and genetic variations may influence the response to PA. Therefore, this study explored Rosae multiflorae fructus (RMF) as a supplement candidate that improves exercise capacity and controls non-alcoholic fatty liver disease (NAFLD) by suppressing lipogenesis and controlling lipid peroxidation.[Methods] RMF is a natural herbal medicine used in Dongui Bogam. RMF has antioxidant, anti-inflammatory, and anti-allergic effects. However, the effects of RMF on NAFLD have not yet been investigated. In this study, we examined the effects of RMF in a mouse model of high-fat diet-induced NAFLD. Mouse livers were isolated and analyzed using H&E staining and immunohistochemistry.[Results] RMF downregulated lipid peroxidation markers, such as CYP2E1, in the livers of mice with high-fat diet-induced NAFLD. Additionally, the RMF significantly reduced the lipid accumulation-related protein expression of CD36, SREBP-1, and PPAR-γ.[Conclusion] RMF exerts anti-lipid peroxidation and anti-lipogenic effects in a high-fat diet-induced NAFLD mouse model.
Investigating Fabry disease - some lessons learned
Authors: Schiffmann Raphael
Published: January 2024

Despite recent advances, there is still much to be learned about the pathogenesis of Fabry disease. The categorization of GLA gene missense mutations has been complicated by the fact that some missense variants may fall into more than one category. For instance, the A143T variant may cause late-onset Fabry disease in some subjects and not result in Fabry disease in others (pseudo-deficient). Efforts to mitigate the pathobiology of α-galactosidase A deficiency should differentiate between damaging (maladaptive) consequences and compensatory (adaptive) changes. Current therapy leaves a significant unmet need, especially concerning cardiovascular complications and cardiological clinical outcomes. Non-Fabry-specific therapy is necessary and quite beneficial and must be utilized. Its contribution should be considered when trying to assess the net effect of Fabry-specific therapy. Enzyme replacement therapy (ERT) can be administered to patients independently of their GLA genotype, as it slows the decline of kidney function in most patients if initiated sufficiently early in the disease course. Migalastat has better tissue penetration than ERT, but its usefulness is restricted to patients with amenable missense GLA variants. However, it is important to realize that in a substantial proportion of common amenable mutations, migalastat increases α-galactosidase A activity level beyond the disease threshold and thus eliminates the metabolic disturbance that is at the center of Fabry disease. Substrate reduction therapy and gene therapy approaches are being developed, but these therapeutic modalities have their own limitations and difficulties.
Potassium fertigation and organic fertilisation in ‘Syrah’ grape in Northeastern Brazil: yield, must characteristics and phenolic compounds
Authors: Oliveira da Silva Alexsandro , Silva Costa Bruno Ricardo , Oldoni Henrique , José Silva Davi , Bassoi Luis Henrique
Published: January 2024

The effect of both potassium and organic fertilisation on grape yield and must composition originating from wine grapevines cultivated in the São Francisco river basin, in the semi-arid region of Northeastern Brazil, is not well known. Since soils from that region usually have low organic matter content, we hypothesise that soil application of organic fertiliser and potassium application through drip irrigation enhances the availability of this nutrient in the soil, and it influences grape yield and quality. Hence, five doses of potassium (0, 20, 40, 80 and 160 kg ha-1) applied through a drip irrigation system and two doses of goat manure as organic fertiliser applied into the soil (0 and 7.5 m3 ha-1) after pruning were evaluated concerning yield and berry quality of grapevine ‘Syrah’ over four growing seasons (April 2013 to July 2015) in Petrolina, state of Pernambuco, Brazil. The experimental design was randomised blocks with 5 replications. We evaluated yield (t ha-1), weight of 100 berries (g), must volume (mL), total soluble solids (°Brix), pH and total titratable acidity (‰), K, Mg and Ca contents and phenolic compounds (total polyphenols, anthocyanins and flavonoids). The increasing application of potassium at the different doses of organic fertiliser did not alter the crop yield, except in the second season. Nonetheless, K concentration in grape must was influenced in the four growing seasons, with higher values at fitted K2O doses by polynomial regression of 83.62 kg ha-1 (first season), 101.25 kg ha-1 (second season), 120.00 kg ha-1 (third season) and 77.99 kg ha-1 (0 m3 ha-1 organic fertiliser) and 96.07 kg ha-1 (7.5 m3 ha-1 organic fertiliser) in the fourth season. The addition of increasing doses of potassium interfered with the wine grape quality, which is an important factor to be considered in relation to its acidity. Organic fertilisation did not affect the most quality characteristics of the grapes.
English Indonesian BilingualAttitudes Toward Codeswitching In Classroom Communication
Authors: Margana Margana
Published: January 2024

This paper deals with the attitudes of English teachers and first grade students toward code-switching in classroom communication at junior high schools in Yogyakarta. It aims to describe their attitudes towards CS and to seek out practical implications for English language teaching and learning in Indonesia. To achieve the objectives, 240 first grade students and60English teachers from selected junior high schools volunteered to participate in this study. They were selected by a purposive sampling technique. Data was gathered thorough questionnaires and analyzed qualitatively and quantitatively using the statistical software of SPPS. The results revealed that(1)CS was positively perceived by participants, and(2) no significant difference in participant attitudes toward CS was found, in terms of gender, age, onset of English study, and teaching experience.
Raising Knowledge Of Illocutionary Acts And Implicatures Used In A Thesis Examination Context For Students Of English Language Education Study Program
Authors: Margana Author:
Published: January 2024

This paper deals with raising knowledge of the illocutionary acts and implied meanings for students of English education study program. It aims to describe the types of illocutionary acts, illocutionary forces, and conversational implicatures used in the thesis examination. Such types of knowledge should be well understood as the knowledge confers a clear description of the use of speech acts in the thesis examination. More specifically, students of English education study programs should be aware of the types of illocutionary acts, namely representatives, directives, commissive, expressive, and declarative which are further classified according to the illocutionary forces of each illocutionary act. Added to this, the knowledge of conversational implicatures: generalised conversational implicatures and particularised conversational implicature are also of great importance to minimise mis-conception and mis-interpretation of speech acts which possible occur in the thesis examination practices.Key words: illocutionary acts illocutionary forces implicatures
The Importance Of Teaching Literature To Students
Authors: Maharsi Ista
Published: January 2024

Literature, in its own self, possesses rich heritage, social, political, philosophical, and economical reflection of an era. It has long been used to depict various circumstances, sound social critiques on a particular condition, reflect characteristics of an age, portray culture of a society, and reveal conspiracy in a country. Literature is widely learned and discussed in schools, yet its benefits and values are often questioned. This paper is aimed to elaborate the idea of the necessity of teaching literature to students and how it can be bought into classrooms.Key words: literature, language, values, students
Establishing American Literature Through James Fenimore Cooper's The Deerslayer
Authors: Agustina Mia Fitria
Published: January 2024

Women have very unique characteristics. They are far different from men. Therefore, women needs are also different from men needs including the need to read. Men tend to read adventure works. The adventure works fulfill man's need to taste the adventure as the hero-individual or group in adventures works is able to overcome obstacles and dangers to accomplish some important and moral mission. In another hand, women prefer to read romance ones. It is because romance formula provides what women desired. Moreover romance works are the feminine equivalent of the adventure stories. Furthermore, chick-lits, the women best friend, is one of the romance works. As it is used romance formula, chick-lits has ability to provide women's desire. It transforms the need, and interprets it through the narrative of chick-lits. That is why, because to find out how the interpretation of the works is an fascinating challenge, this paper tries to see the connection between chick-lits romance formula and how it affects the readers, the women.Key words: chick-lits, women, romance formula, and the needs
The Hidden Loopholes Undermining Photonic Quantum Nonlocality: Quantum Rayleigh Scattering and Time-Dependent Multi-Photon Pure States of Independent Photons
Authors: Vatarescu Andre
Published: January 2024

The locality condition of probabilities underpinning the derivation of Bell inequalities can be violated classically. The wave function collapse results in the factorization of quantum probabilities. It is possible to differentiate, locally, between ensemble probabilities of single detections with and without wave function collapse for the alleged quantum nonlocality. The theoretical concept of photonic quantum nonlocality cannot be implemented physically because of the quantum Rayleigh scattering of single photons. A distinction needs to be made between the correlation of individual, single measurements of pure states and the correlation of the ensemble states of the mixed states. The correlation operator of Pauli vector operators delivers the same probabilities of correlated detections of photons for both independent and multi-photon states as for ‘entangled’ states of photons. As single-photon sources are not needed, the design and implementation of quantum computing operations and other devices will be significantly streamlined.
Alena Tensor and Its Possible Applications in Unification Theories
Authors: Ogonowski Piotr , Skindzier Piotr
Published: January 2024

The Alena Tensor is a recently discovered class of energy-momentum tensors that provides a mathematical framework in which the description of a physical system in curved spacetime and its description in a flat spacetime with fields are equivalent. As demonstrated in previous publications, in curved spacetime this tensor reproduces Einstein Field Equations and in flat Minkowski spacetime, it describes a physical system with fields that can be widely configured. The use of the discussed tensor may significantly simplify Quantum Field Theory equations and it also provides canonical, generalized four-momentum with vanishing four-divergence that satisfies Klein-Gordon equation. This article discusses the perspectives of application of Alena Tensor in unification theories against the background of existing research directions.
Control the Coefficient of a Differential Equation as an Inverse Problem in Time
Authors: TERNOVSKI VLADIMIR , ILYUTKO VICTOR
Published: January 2024

There are many problems based on solving non-autonomous differential equations of the form x¨(t)+ω2(t)x(t)=0, where x(t) represents the coordinate of a material point and ω is the angular frequency. The inverse problem involves finding the bounded coefficient ω. Continuity of the function ω(t) is not required. The trajectory x(t) is unknown, but the initial and final values of the phase variables are given. The variation principle of minimum time for the entire dynamic process allows for the determination of the optimal solution {x(t),ω(t)}. Thus, the inverse problem is an optimal control problem. No simplifying assumptions were made.
The Impact of Social Support and Resilience on Stress and Quality of Life in Cancer Patients Receiving Immunotherapy
Authors: Ruiz-Rodríguez Iván , Melguizo-Garín Anabel
Published: January 2024

The treatment of cancer and associated healthcare procedures often impose a detrimental effect on patients’ quality of life. Symptoms stemming from treatment often hinder patients’ social interactions, emphasizing the crucial role of social support in preserving quality of life and alleviating stress. Moreover, patient resilience serves as a valuable asset in mitigating stress levels and upholding an optimal quality of life amidst the challenges posed by the illness. This study aims to explore the correlation between diverse sources and forms of social support, resilience, and their impact on the quality of life and stress levels among patients undergoing cancer immunotherapy. This study involved thirty patients undergoing immunotherapy at Costa del Sol Hospital in Marbella. Resilience correlated with improved cognitive functioning and diminished symptoms. Informational support from healthcare providers and emotional support from friends were linked to symptom alleviation, such as reduced appetite and insomnia. Moreover, emotional support from friends emerged as a predictor for decreased perceived stress. Interventions targeting the improvement of quality of life and reduction of stress among cancer patients should prioritize assessing support needs and involving the patient's social network, especially during the treatment phase.
Revealing the Impact of Ga/Y Doping on the Thermal and Electrical Behavior in LaMnO3 Ceramics Materials
Authors: Vlazan Paulina , Malaescu Iosif , Marin Catalin Nicolae , Poienar Maria , Vlase Gabriela , Vlase Titus , Sfirloaga Paula
Published: January 2024

In this work, we report a series of undoped and 1% Ga or Y doped lanthanum manganite compounds which have been synthesized via sol-gel technique. The obtained materials were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and scanning electron microscopy (SEM/EDX). The XRD results confirmed a good crystallinity for all the studied samples and a change in the crystal structure of Ga or Y doped lanthanum manganite (Pm-3m space group) is observed compared to pristine sample (R-3c space group). Thermal analysis highlighted a different behavior of the doped samples compared to the undoped sample observed by the different mass loss in the analyzed temperature range. For these materials, it is shown for the first time that the static electrical conductivity, σDC of Ga or Y doped LaMnO3 compounds increases compared to the σDC pristine sample, and the thermal activation energy of the conduction EA,cond increases linearly with the temperature, for all three studied sample.
Hovenia dulcis Fruit Peduncle Polysaccharides Reduce Intestinal Dysbiosis and Hepatic Fatty Acid Metabolism Disorders in Alcohol-Exposed Mice
Authors: Liu Liangyu , Zhu Sijie , Zhang Yuchao , Zhu Zhenyuan , Xue Yong , Liu Xudong
Published: January 2024

Alcohol abuse can lead to alcoholic liver disease, becoming a major global burden. Hovenia dulcis fruit peduncle polysaccharides (HDPs) has the potential to alleviate alcoholic liver injury may play essential roles in treating for alcohol-exposed liver disease, however, the hepatoprotective effects and mechanisms remain unclear. In this study, the hepatoprotective effects of HDPs and its potential mechanisms were investigated in alcohol-exposed mice by liver metabolomics and gut microbiome. The results found that HDPs reduced medium-dose alcohol-caused dyslipidemia (significantly elevated T-CHO, TG, LDL-C), elevated liver glycogen levels and inhibited intestinal-hepatic inflammation (significantly decreased IL-4, IFN-γ and TNF-α), consequently reversing hepatic pathological changes. By applying gut microbiome analysis, HDPs showed significant decreases in Proteobacteria while significant increases in Firmicutes at the phylum level, and increased Lactobacillus abundance while decreased Enterobacteria abundance, maintaining the composition of gut microbiota. Further hepatic metabolomics analysis revealed that HDPs had a regulatory effect on hepatic fatty acid metabolism, by increasing the major metabolic pathways including arachidonic acid metabolism and glycerophospholipid metabolism and identified two important metabolites C00157 and C04230 involved in the above metabolism. Overall, HDPs reduced intestinal dysbiosis and hepatic fatty acid metabolism disorders in alcohol-exposed mice, suggesting that HDPs has a beneficial effect on alleviating alcohol-induced hepatic metabolic disorders.
Selective Heterogeneous Fenton Degradation of Formaldehyde Using the Fe-ZSM-5 Catalyst
Authors: Zhou Peiguo , Hou Jiaxin , Zhang Donghui , Liao Ziqiao , Yang Liping , Yang Wenjing , Ru Xin , Dai Zongbiao
Published: January 2024

As one of toxic Volatile Organic Pollutant (TVOCs), formaldehyde has a toxic effect on microorganisms, and then inhibits the biochemical process of formaldehyde wastewater treatment. Therefore, the selective degradation of formaldehyde is of great significance to achieve formaldehyde wastewater high-efficiency and low-cost treatment. This study constructed a heterogeneous Fe-ZSM-5/H2O2 Fenton system for selective degradation to target compounds. By bonding Fe3+ onto the surface of ZSM-5 molecular sieve, Fe-ZSM-5 was prepared successfully. XRD, BET and FT-IR spectral studies shown the prepared Fe-ZSM-5 was mainly composed of micropores. The influences of different variables on formaldehyde selective heterogeneous Fenton degradation performance were studied. The 93.72% formaldehyde degradation and the 98.15% selectivity of formaldehyde compared with glucose had demonstrated in the optimized Fenton system after 360 min. Notably, the resultant selective Fenton oxidation system had a wide range of pH suitability from 3.0 to 10.0. Also, the Fe-ZSM-5 was used in 5 consecutive cycles, while the degradation efficiency of formaldehyde did not drop dramatically. Using reactive oxygen species scavengers, hydroxyl radical was the main active substance to degrade formaldehyde. Furthermore, the great degradation performance of this system to high concentration of formaldehyde was acquired, and the degrading efficiency was more than 95%.