bluuebunny/crossref_metadata_2025 huggingface dataset:
A retrospective analysis of respiratory virus transmission before and during the COVID-19 pandemic in Pune the western region of India
Authors: Bhardwaj Sumit , Choudhary Manohar Lal , Jadhav Sheetal , Vipat Veena , Ghuge Rohan , Salvi Sonali , Kulkarni Rajesh , Kinikar Aarti , Padbidri Vikram , Bafna Sanjay , Bavdekare Ashish , D'costa Pradeep , Gujar Nilesh , Potdar Varsha
Published: September 2022

Background

SARS-CoV-2 was first reported in China in December 2019 and quickly spread across the world. Non-pharmaceutical interventions (NPIs) are the key to control the transmission of respiratory viruses. To stop the spread, NPI is widely recommended and is still followed by most countries.

Methods

At the National Influenza Center of the Indian Council of Medical Research-National Institute of Virology (ICMR-NIV), the surveillance of severe acute respiratory illness and acute respiratory illness cases for influenza and other respiratory viruses is in place. In this study, we analyzed surveillance data on respiratory viruses and/or SARS-CoV-2 testing from January 2017 to December 2021. Multiplex real-time PCR was used to detect the respiratory viruses.

Results

Our findings indicate that during the pandemic, the positivity for influenza A and B, metapneumovirus, parainfluenza virus, respiratory syncytial virus, and human coronavirus declined significantly.

Conclusion

The annual distinct seasonal outbreaks of influenza, RSV, and other respiratory viruses as observed during the pre-COVID-19 period were not observed during the COVID-19 pandemic in years 2020 and 21. Social distancing, lock-downs, and non-pharmaceutical interventions may play an important role in the reduction of respiratory viruses. Understanding the seasonal respiratory virus decline could help public health experts prepare for future respiratory virus pandemics.
Ways of HIV transmission in China: The effect of age, period, and cohort
Authors: Wang Tang , Gu Yaohua , Ran Li , Tan Xiaodong , Peng Shuzhen
Published: September 2022

Background

Acquired immunodeficiency syndrome (AIDS) is a global pandemic caused by human immunodeficiency virus (HIV), which is transmitted through human behaviors, such as sexual intercourse, intravenous drug injection, and blood transfusion. Rare studies have focused on the evaluation of the effects of culture, society, and HIV-related policies in adjusting people's HIV-related behaviors, i.e., ways of HIV transmission.

Methods

By taking the new HIV infections in Hubei Province each year from 1995 to 2020 as the sample, our study used the Hierarchical Age-Period-Cohort (HAPC) model to analyze the effects of age, period, and cohort on the trends of ways of HIV transmission.

Results

From 1995 to 2020, the number of new HIV infections in Hubei presented a general upward trend. A total of 34,636 HIV infections were reported during this period. According to the statistics of the new HIV infections in Hubei Province between 1995 and 2020, there is a negative correlation between age (−0.099, p < 0.001), squared age (−0.002, p < 0.001), and the rate of blood transmission. While there is a positive correlation between age (0.143, p < 0.001), squared age (0.002, p < 0.001), and the rate of HIV infection through sexual transmission. The significant period and cohort effects on ways of HIV transmission were also observed in the Chinese population.

Conclusion

Sexual and blood transmission are the two main ways of HIV infection in China and Hubei. The trend of blood transmission is in accordance with the wave of blood trade in the early 1990s in China. The trend of sexual transmission indicates an increasing need to promote safer sexual behavior among the older population and later generations and design more tailored, innovative, and diverse HIV prevention strategies, especially for the high-risk groups.
The Use of a Log-Normal Prior for the Student t-Distribution
Authors: Lee Se Yoon
Published: September 2022

It is typically difficult to estimate the number of degrees of freedom due to the leptokurtic nature of the Student t-distribution. Particularly in studies with small sample sizes, special care is needed concerning prior choice in order to ensure that the analysis is not overly dominated by any prior distribution. In this article, popular priors used in the existing literature are examined by characterizing their distributional properties on an effective support where it is desirable to concentrate on most of the prior probability mass. Additionally, we suggest a log-normal prior as a viable prior option. We show that the Bayesian estimator based on a log-normal prior compares favorably to other Bayesian estimators based on the priors previously proposed via simulation studies and financial applications.
Analysis of Peukert Generalized Equations Use for Estimation of Remaining Capacity of Automotive-Grade Lithium-Ion Batteries
Authors: Yazvinskaya Nataliya N. , Lipkin Mikhail S. , Galushkin Nikolay E. , Galushkin Dmitriy N.
Published: September 2022

In this paper, it is shown that the Peukert generalized equations C = Cm/(1 + (i/i0)n), C = 0.522Cmtanh((i/i0)n/0.522)/(i/i0)n and C = Cmerfc((i/ik − 1)/(1/n))/erfc(−n) are applicable for capacity estimation of the automotive-grade lithium-ion batteries within the discharge current range, from 0 to 10 Cn. Additionally, it is shown here that all the parameters (Cm, n, i0 and ik) in the Peukert generalized equations under study have a clear physical meaning, unlike in the classical Peukert equation, in which all the parameters are just empirical constants. In addition, it is shown that, in the case of lithium-ion batteries, the dependence of their released capacity on the discharge current reflects the phase transition statistical pattern in the electrodes’ active substance, which follows the normal distribution law. As the Peukert equation is used in many analytical models, the better electrochemical and physical meaning and understanding of this equation and its clarification are of great practical importance.
Pitavastatin and Ivermectin Enhance the Efficacy of Paclitaxel in Chemoresistant High-Grade Serous Carcinoma
Authors: Nunes Mariana , Duarte Diana , Vale Nuno , Ricardo Sara
Published: September 2022

Chemotherapy is a hallmark in high-grade serous carcinoma management; however, chemoresistance and side effects lead to therapeutic interruption. Combining repurposed drugs with chemotherapy has the potential to improve antineoplastic efficacy, since drugs can have independent mechanisms of action and suppress different pathways simultaneously. This study aimed to explore whether the combination of Paclitaxel with repurposed drugs led to a therapeutic benefit. Thus, we evaluated the cytotoxic effects of Paclitaxel alone and in combination with several repurposed drugs (Pitavastatin, Metformin, Ivermectin, Itraconazole and Alendronate) in two tumor chemoresistant (OVCAR8 and OVCAR8 PTX R P) and a non-tumoral (HOSE6.3) cell lines. Cellular viability was assessed using Presto Blue assay, and the synergistic interactions were evaluated using Chou–Talalay, Bliss Independence and Highest Single Agent reference models. The combination of Paclitaxel with Pitavastatin or Ivermectin showed the highest cytotoxic effect and the strongest synergism among all combinations for both chemoresistant cell lines, resulting in a chemotherapeutic effect superior to both drugs alone. Almost all the repurposed drugs in combination with Paclitaxel presented a safe pharmacological profile in non-tumoral cells. Overall, we suggest that Pitavastatin and Ivermectin could act synergistically in combination with Paclitaxel, being promising two-drug combinations for high-grade serous carcinoma management.
SPP1 Derived from Macrophages Is Associated with a Worse Clinical Course and Chemo-Resistance in Lung Adenocarcinoma
Authors: Matsubara Eri , Komohara Yoshihiro , Esumi Shigeyuki , Shinchi Yusuke , Ishizuka Shiho , Mito Remi , Pan Cheng , Yano Hiromu , Kobayashi Daiki , Fujiwara Yukio , Ikeda Koei , Sakagami Takuro , Suzuki Makoto
Published: September 2022

Osteopontin, also called secreted phosphoprotein 1 (SPP1), is a multifunctional secreted phosphorylated glycoprotein. SPP1 is also expressed in tumor cells, and many studies demonstrated that a high level of circulating SPP1 is correlated with a poor prognosis in various cancers. SPP1 is expressed not only by tumor cells but also by stromal cells, such as macrophages. However, there have been no studies distinguishing the SPP1 expression of cancer cells and tumor-associated macrophages (TAMs). Thus, in this study, we tried to accurately evaluate the SPP1 expression status on cancer cells and TAMs separately in patients with non-small cell lung cancer by using double immunohistochemistry. We demonstrated that high SPP1 expression on TAMs predicted a poor prognosis in lung adenocarcinoma patients. Additionally, we investigated the expression mechanisms related to SPP1 using human-monocyte-derived macrophages and revealed that the SPP1 expression level increased in macrophage differentiation mediated by granulocyte-macrophage colony-stimulating factor. Furthermore, SPP1 contributed to anti-cancer drug resistance in lung cancer cell lines. In conclusion, SPP1 production on TAMs predicted a poor prognosis in lung adenocarcinoma patients, and TAM-derived SPP1′s involvement in the chemo-resistance of cancer cells was suggested.
In Vivo Application of CRISPR/Cas9 Revealed Implication of Foxa1 and Foxp1 in Prostate Cancer Proliferation and Epithelial Plasticity
Authors: Cai Huiqiang , Agersnap Simon N. , Sjøgren Amalie , Simonsen Mikkel K. , Blaavand Mathilde S. , Jensen Ulrikke V. , Thomsen Martin K.
Published: September 2022

Prostate cancer is the most common cancer in men in the Western world and the number is rising. Prostate cancer is notoriously heterogeneous, which makes it hard to generate and study in pre-clinical models. The family of Forkhead box (FOX) transcription factors are often altered in prostate cancer with especially high mutation burden in FOXA1 and FOXP1. FOXA1 harbors loss or gain of function mutations in 8% of prostate cancer, which increases to 14% in metastatic samples. FOXP1 predominately occurs with loss of function mutations in 7% of primary tumors, and similar incidents are found in metastatic samples. Here, we applied in vivo CRISPR editing, to study the loss of functions of these two FOX transcription factors, in murine prostate in combination with loss of Pten. Deficiency of Foxp1 increased proliferation in combination with loss of Pten. In contrast, proliferation was unchanged when androgen was deprived. The expression of Tmprss2 was increased when Foxp1 was mutated in vivo, showing that Foxp1 is a repressor for this androgen-regulated target. Furthermore, analysis of FOXP1 and TMPRSS2 expression in a human prostate cancer data set revealed a negative correlation. Mutation of Foxa1 in the murine prostate induces cell plasticity to luminal cells. Here, epithelial cells with loss of Foxa1 were transdifferentiated to cells with expression of the basal markers Ck5 and p63. Interestingly, these cells were located in the lumen and did not co-express Ck8. Overall, this study reveals that loss of Foxp1 increases cell proliferation, whereas loss of Foxa1 induces epithelial plasticity in prostate cancer.
Detection of Mutations in pncA in Mycobacterium tuberculosis Clinical Isolates from Nepal in Association with Pyrazinamide Resistance
Authors: Shrestha Dipti , Maharjan Bhagwan , Thapa Jeewan , Akapelwa Mwangala Lonah , Bwalya Precious , Chizimu Joseph Yamweka , Nakajima Chie , Suzuki Yasuhiko
Published: September 2022

Without the proper information on pyrazinamide (PZA) susceptibility of Mycobacterium tuberculosis (MTB), PZA is inappropriately recommended for the treatment of both susceptible and multidrug-resistant tuberculosis (MDR-TB) in Nepal. This study aimed to collect information regarding PZA susceptibility in MTB isolates from Nepal by analyzing pncA and its upstream regulatory region (URR). A total of 211 MTB isolates were included in this study. Sequence analysis of pncA and its URR was performed to assess PZA resistance. First-line drug susceptibility testing, spoligotyping, and sequence analysis of rpoB, katG, the inhA regulatory region, gyrA, gyrB, and rrs were performed to assess their association with pncA mutation. Sequencing results reveal that 125 (59.2%) isolates harbored alterations in pncA and its URR. A total of 57 different mutation types (46 reported and 11 novel) were scattered throughout the whole length of the pncA gene. Eighty-seven isolates (41.2%) harbored mutations in pncA, causing PZA resistance in MTB. There was a more significant association of pncA alterations in MDR/pre-extensively drug-resistant (Pre-XDR) TB than in mono-resistant/pan-susceptible TB (p < 0.005). This first report on the increasing level of PZA resistance in DR-TB in Nepal highlights the importance of PZA susceptibility testing before DR-TB treatment.
Updates in Pathology for Retroperitoneal Soft Tissue Sarcoma
Authors: Mack Tanner , Purgina Bibianna
Published: September 2022

Retroperitoneal tumors are extremely rare. More than 70% of primary retroperitoneal soft tissue tumors are malignant. The most common sarcomas in the retroperitoneum include liposarcomas and leiomyosarcoma, however other sarcomas, along with benign mesenchymal tumors, can occur. Sarcomas are a heterogenous group of tumors with overlapping microscopic features, posing a diagnostic challenge for the pathologist. Correct tumor classification has become important for prognostication and the evolving targeted therapies for sarcoma subtypes. In this review, the pathology of retroperitoneal soft tissue sarcomas is discussed, which is important to the surgical oncologist. In addition, less common sarcomas and benign mesenchymal tumors of the retroperitoneum, which may mimic sarcoma clinically and pathologically, are also discussed.
13C-Labeled Artificial Root Exudates Are Immediately Respired in a Peat Mesocosm Study
Authors: Müller Raphael , Maier Andreas , Inselsbacher Erich , Peticzka Robert , Wang Gang , Glatzel Stephan
Published: September 2022

Globally, peatlands have been recognized as important carbon sinks while only covering approximately 3% of the earth’s land surface. Root exudates are known key drivers of C cycling in soils and rhizosphere priming effects have been studied extensively in terrestrial ecosystems. Their role for decomposition of peat still remains unclear, as little research about their fate and potential priming effects in peat exists. In this study, we aimed to evaluate pathways of root exudates and their short-term priming effects by daily determination of stable carbon isotope fluxes of CO2 and CH4. As the drainage of peatlands strongly alters processes of decomposition, we included measurements after drainage as well. Results revealed the immediate respiration of root exudates in peat, mainly as CO2, while CH4 release was associated with a lag time of several days. However, the largest proportion of added root exudates remained in the solid and liquid phase of peat. In conclusion, our findings suggest that no priming occurred as added substrates remained immobile in peat.
Discrimination of Mangrove Stages Using Multitemporal Sentinel-1 C-Band Backscatter and Sentinel-2 Data—A Case Study in Samut Songkhram Province, Thailand
Authors: Upakankaew Kamonporn , Ninsawat Sarawut , Virdis Salvatore G. P. , Sasaki Nophea
Published: September 2022

Discrimination of mangrove stage changes is useful for the conservation of this valuable natural resource. However, present-day optical satellite imagery is not fully reliable due to its high sensitivity to weather conditions and tidal variables. Here, we used the Vertical Transmit—Vertical Receive Polarization (VV) and Vertical Transmit—Horizontal Receive Polarization (VH) backscatter from the same and multiple-incidence angles from Sentinel-1 SAR C-band along with Normalized Difference Vegetation Index (NDVI), Normalized Difference Water Index (NDWI), Normalized Difference Moisture Index (NDMI), Normalized Difference Red Edge (NDVIRE) and Chlorophyll Index Green (CIGreen) from the optical satellite imageries from Sentinel-2 to discriminate between the changes in disturbance, recovery, and healthy mangrove stages in Samut Songkhram province, Thailand. We found the mean NDVI values to be 0.08 (±0.11), 0.19 (±0.09), and −0.53 (±0.16) for the three stages, respectively. We further found their correlation with VH backscatter from the multiple-incidence angles at about −17.98 (±2.34), −16.43 (±1.59), and −13.40 (±1.07), respectively. The VH backscatter from multiple-incidence angles was correlated with NDVI using Pearson’s correlation (𝑟2 = 0.62). However, Pearson’s correlation of a single plot (ID2) of mangrove stage change from disturbance to recovery, and then on to the healthy mangrove stage, displayed a 𝑟2 of 0.93 (p value is less than 0.0001, n = 34). This indicated that the multitemporal Sentinel-1 C-band backscatter and Sentinel-2 data could be used to discriminate mangrove stages, and that a reduced correlation to significant observations was the result of variations in both optical and SAR backscatter data.
Forest Recreation and Landscape Protection
Authors: Pintilii Radu-Daniel
Published: September 2022

Forests, which are viewed as an important natural resource for humanity, have been constantly threatened with degradation or even extinction since the dawn of the modern period [...]
Regulatory Control and the Effects of Condensation Water on Water Migration and Reverse Migration of Halostachys caspica (M.Bieb.) C.A.Mey. in Different Saline Habitats
Authors: Qin Lu , He Xuemin , Lv Guanghui , Yang Jianjun
Published: September 2022

Condensation water has been a recent focus in ecological hydrology research. As one of the main water sources that maintains the food chain in arid regions, condensation water has a significant impact on water balance in arid environments and plays an important role in desert vegetation. This study takes drought desert areas and high-salinity habitats as its focus—selecting Halostachys caspica (M.Bieb.) C.A.Mey. and its community in mild, moderate, and severe salinity soil—analyzed the source of condensation water utilized by these plants, and calculated its percentage of contribution. I. Study results revealed: (1) Scale-like leaves can absorb condensation water and the order of condensation water contribution to plant growth in different salinity habitats are severe > mild > moderate, such that the average contribution rates were 11.13%, 7.10%, and 3.79%, respectively; (2) The migration path of water movement in these three communities are formed in two main ways: (a) rain and condensation water recharge the soil to compensate for groundwater, while some groundwater compensates for river water and partially returns to the atmosphere by soil evaporation and plant transpiration; and (b) rain and condensation water directly compensate for river water and plant roots absorb river water, groundwater, and soil water in order to grow; (3) in mild habitats, the water movement path in plants is as follows: shallow root → stem → branches → leaves and shallow root → deep root; (4) in moderate habitats, stems act as the bifurcation point and the path follows as: stem → branches → leaves and stem → shallow root → deep root; and (5) in severe habitats, the path is as follows: deep root → shallow root → stem → branches → leaves, and finally returning to the atmosphere. These results elucidate the contribution of condensation water on Halostachys caspica growth and the migration path through the Halostachys caspica body. Condensation water obtained by Halostachys caspica communities in different salinity habitats provides a theoretical basis and data supporting the need for future research of condensation water on plants at the physiological level in arid regions and provides reference for the protection of saline soil and its ecological environment in arid regions.
Retrieving Adversarial Cliques in Cognitive Communities: A New Conceptual Framework for Scientific Knowledge Graphs
Authors: Fabre Renaud , Azeroual Otmane , Bellot Patrice , Schöpfel Joachim , Egret Daniel
Published: September 2022

The variety and diversity of published content are currently expanding in all fields of scholarly communication. Yet, scientific knowledge graphs (SKG) provide only poor images of the varied directions of alternative scientific choices, and in particular scientific controversies, which are not currently identified and interpreted. We propose to use the rich variety of knowledge present in search histories to represent cliques modeling the main interpretable practices of information retrieval issued from the same “cognitive community”, identified by their use of keywords and by the search experience of the users sharing the same research question. Modeling typical cliques belonging to the same cognitive community is achieved through a new conceptual framework, based on user profiles, namely a bipartite geometric scientific knowledge graph, SKG GRAPHYP. Further studies of interpretation will test differences of documentary profiles and their meaning in various possible contexts which studies on “disagreements in scientific literature” have outlined. This final adjusted version of GRAPHYP optimizes the modeling of “Manifold Subnetworks of Cliques in Cognitive Communities” (MSCCC), captured from previous user experience in the same search domain. Cliques are built from graph grids of three parameters outlining the manifold of search experiences: mass of users; intensity of uses of items; and attention, identified as a ratio of “feature augmentation” by literature on information retrieval, its mean value allows calculation of an observed “steady” value of the user/item ratio or, conversely, a documentary behavior “deviating” from this mean value. An illustration of our approach is supplied in a positive first test, which stimulates further work on modeling subnetworks of users in search experience, that could help identify the varied alternative documentary sources of information retrieval, and in particular the scientific controversies and scholarly disputes.
Complete Chloroplast Genome of Gladiolus gandavensis (Gladiolus) and Genetic Evolutionary Analysis
Authors: Qian Renjuan , Ye Youju , Hu Qingdi , Ma Xiaohua , Zheng Jian
Published: September 2022

Gladiolus is an important ornamental plant that is one of the world’s four most-grown cut flowers. Gladiolus gandavensis has only been found in the Cangnan County (Zhejiang Province) of China, which is recorded in the “Botanical”. To explore the origin of G. gandavensis, chloroplast genome sequencing was conducted. The results indicated that a total of 151,654 bp of circular DNA was obtained. The chloroplast genome of G. gandavensis has a quadripartite structure (contains a large single-copy (LSC) region (81,547 bp), a small single-copy region (SSC) (17,895 bp), and two inverted repeats (IRs) (IRa and IRb, 52,212 bp)), similar to that of other species. In addition, a total of 84 protein-coding genes, 8 rRNA-encoding genes, and 38 tRNA-encoding genes were present in the chloroplast genome. To further study the structural characteristics of the chloroplast genome in G. gandavensis, a comparative analysis of eight species of the Iridaceae family was conducted, and the results revealed higher similarity in the IR regions than in the LSC and SSC regions. In addition, 265 simple sequence repeats (SSRs) were detected in this study. The results of the phylogenetic analysis indicated that the chloroplast genome of G. gandavensis has high homology with the Crocus cartwrightianus and Crocus sativus chloroplast genomes. Genetic analysis based on the rbcl sequence among 49 Gladiolus species showed that samples 42, 49, 50, and 54 had high homology with the three samples from China (64, 65, and 66), which might be caused by chance similarity in genotypes. These results suggest that G. gandavensis may have originated from South Africa.
“The Last Thing You Have to Worry About”: A Thematic Analysis of Employment Challenges Faced by Cancer Survivors
Authors: Lyons Kathleen Doyle , Forcino Rachel C. , Rotenberg Sivan , Schiffelbein Jenna E. , Morrissette Kali J. , Godzik Cassandra M. , Lichtenstein Jonathan D.
Published: September 2022

The evidence base for interventions that support the employment goals of cancer survivors is growing but inconclusive. As the first step in initiating a community-engaged program of research aimed at developing and testing interventions to support the employment goals of cancer survivors, 23 cancer survivors, 17 healthcare providers, and 5 employers participated in individual interviews to elicit perceptions regarding local challenges and resources related to work maintenance and optimization within the context of cancer treatment. Interviews were recorded and transcribed verbatim. A thematic analysis was conducted to identify cross-cutting experiences that were voiced by all three types of participants. Three themes were found in the data: (1) the onus for identifying and articulating work-related issues is upon the cancer survivor; (2) the main support offered to cancer survivors involved time away from work and flexibility with scheduling work and treatment activities; and (3) participants voiced a lack of information regarding one or more aspects related to supporting employment goals of cancer survivors. Supportive resources designed for cancer survivors, employers, and/or healthcare providers are needed to help cancer survivors optimize their employment situations.
Media Exposure to Armed Conflict: Dispositional Optimism and Self-Mastery Moderate Distress and Post-Traumatic Symptoms among Adolescents
Authors: Pe’er Ayelet , Slone Michelle
Published: September 2022

Background: Rapid technological developments enable the immediate transmission of armed conflict events through a variety of media channels, inducing mass anxiety, fear, and helplessness. Youth are particularly vulnerable and face new challenges as a result of this exposure. The effects of media exposure to such events on psychological distress and post-traumatic symptoms were examined. Methods: A total of 161 participants aged 13–18 years completed a questionnaire battery that included measures of media exposure to armed conflict events, previous direct exposure to armed conflict events, psychological distress, post-traumatic symptoms, dispositional optimism, and self-mastery. A structural equation model (SEM) approach was employed for data analysis. Results: The extent of media exposure to armed conflict was directly associated with psychological distress and post-traumatic symptoms. Dispositional optimism moderated the association between media exposure and psychological distress, while self-mastery moderated the association between media exposure and post-traumatic symptoms. The effects of the Internet factor of media exposure, which included social media, were particularly disturbing as neither of the resilience factors moderated negative outcomes. Conclusions: The findings suggest that clinical interventions to enhance dispositional optimism and self-mastery as well as other potential resilience factors can protect adolescents from the severe effects of media exposure to violent armed conflict events. Developmental and public health implications related to vulnerabilities and resilience during adolescence are discussed.
Do Different Patterns of Employment Quality Contribute to Gender Health Inequities in the U.S.? A Cross-Sectional Mediation Analysis
Authors: Peckham Trevor , Seixas Noah , de Castro A. B. , Hajat Anjum
Published: September 2022

Compared to recent generations, workers today generally experience poorer quality employment across both contractual (e.g., wages, hours) and relational (e.g., participation in decision-making, power dynamics) dimensions within the worker–employer relationship. Recent research shows that women are more likely to experience poor-quality employment and that these conditions are associated with adverse health effects, suggesting employment relations may contribute to gender inequities in health. We analyzed data from the General Social Survey (2002–2018) to explore whether the multidimensional construct of employment quality (EQ) mediates the relationship between gender and health among a representative, cross-sectional sample of U.S. wage earners. Using a counterfactually-based causal mediation framework, we found that EQ plays a meaningful role in a gender–health relationship, and that if the distribution of EQ among women was equal to that observed in men, the probability of reporting poor self-reported health and frequent mental distress among women would be lower by 1.5% (95% Confidence Interval: 0.5–2.8%) and 2.6% (95% CI: 0.6–4.6%), respectively. Our use of a multidimensional, typological measure of EQ allowed our analysis to better account for substantial heterogeneity in the configuration of contemporary employment arrangements. Additionally, this study is one of the first mediation analyses with a nominal mediator within the epidemiologic literature. Our results highlight EQ as a potential target for intervention to reduce gender inequities in health.
Relationship between Different Dimensions of Workplace Spirituality and Psychological Well-Being: Measuring Mediation Analysis through Conditional Process Modeling
Authors: Ahmed Rizwan Raheem , Soomro Farwa Abbas , Channar Zahid Ali , Hashem E Alharthi Rami , Soomro Hassan Abbas , Pahi Munwar Hussain , Md Salleh Nor Zafir
Published: September 2022

The present study aims to identify the relationship between workplace spirituality, compassion, relationship with others at work, spiritual orientation, organizational value and alignment of personal values, and psychological well-being among universities’ teachers. Further, the mediating effect of job stress was also identified between workplace spirituality and psychological well-being. Similarly, the mediation of environmental mastery between organizational values and alignment of personal values and psychological well-being was examined. Finally, we examined the mediation of personal growth between spiritual orientation and psychological well-being. The data were collected through a structured and adapted five-point Likert scale using a purposive sampling technique, with a total sample of 873 male and female university teachers working in the private and government universities. We employed structural equation modeling to check the relationship among the considered variables for analysis purposes. The results show a strong positive relationship between the independent and dependent variables. The findings further demonstrated that the mediation analysis confirms that job stress mediates the relationship between workplace spirituality and psychological well-being, and environmental mastery mediates between organizational values and alignment of personal values and psychological well-being. Finally, personal growth mediates between spiritual orientation and psychological well-being. To maintain the excellent quality of education, educational institutes need to identify and imply the practice of workplace spirituality that will help to reduce job stress and improve the psychological well-being of universities’ teachers, thus resulting in better educational output.
Quantifying the Relationship between SARS-CoV-2 Wastewater Concentrations and Building-Level COVID-19 Prevalence at an Isolation Residence: A Passive Sampling Approach
Authors: Acer Patrick T. , Kelly Lauren M. , Lover Andrew A. , Butler Caitlyn S.
Published: September 2022

SARS-CoV-2 RNA loads can be detected in the excreta of individuals with COVID-19 and have demonstrated positive correlations with clinical infection trends. Consequently, wastewater-based epidemiology (WBE) approaches have been implemented globally as a public health surveillance tool to monitor community-level prevalence of infections. The majority of wastewater specimens are gathered as either composite samples via automatic samplers (autosamplers) or grab samples. However, autosamplers are expensive and can be challenging to maintain in cold weather, while grab samples are particularly susceptible to temporal variation when sampling sewage directly from complex matrices outside residential buildings. Passive sampling can provide an affordable, practical, and scalable sampling system while maintaining a reproducible SARS-CoV-2 signal. In this regard, we deployed tampons as passive samplers outside of a COVID-19 isolation unit (a segregated residence hall) at a university campus from 1 February 2021–21 May 2021. Samples (n = 64) were collected 3–5 times weekly and remained within the sewer for a median duration of 24 h. SARS-CoV-2 RNA was quantified using reverse-transcription quantitative polymerase chain reaction (RT-qPCR) targeting the N1 and N2 gene fragments. We quantified the mean viral load captured per individual and the association between the daily viral load and total persons, adjusting for covariates using multivariable models to provide a baseline estimate of viral shedding. Samples were processed through two distinct laboratory pipelines on campus, yielding highly correlated N2 concentrations. Data obtained here highlight the success of passive sampling utilizing tampons to capture SARS-CoV-2 in wastewater coming from a COVID-19 isolation residence, indicating that this method can help inform building-level public health responses.
Active Indoor Soundscape Design: A Case Study of Ceramic Passive Amplifiers
Authors: Li Feng , Xiang Jiali , Li Tao , Shen Danni , Li Tian
Published: September 2022

Indoor soundscape research has developed rapidly in recent years, with the aim of improving the single indoor noise reduction method and people’s acoustic comfort. However, practical solutions to promote the generation of positive indoor soundscapes are still insufficient. The purpose of this study was to explore the improvement effect of ceramic passive amplifiers on the indoor soundscape and the relationship between the improvement effect and different amplifier shapes. Objective sound pressure level (SPL) values and subjective soundscape perception were measured for 10 ceramic passive amplifiers based on the soundscape, mainly using a comparative method. Ten sample amplifiers were compared with the acoustic data of the original open-plan studio environment, and then with an electronic sound amplifier. The results show that ceramic passive amplifiers can improve the quality of the indoor soundscape by creating sound scenes with appropriate loudness. Regarding non-acoustic aspects, the shape and materials of ceramic passive amplifiers play a positive role in emotional guidance.
Key Considerations to the Introduction of Intergenerational Practice to Australian Policy
Authors: Radford Katrina , Fitzgerald Janna Anneke , Vecchio Nerina , Cartmel Jennifer , Gould Ryan Bruce , Kosiol Jennifer
Published: September 2022

Intergenerational practice programs provide purposeful interactions between generations. While research reports improved social and behavioral outcomes for cohorts, no study has explored both expert and potential consumer perceptions of the implementation of intergenerational practice programs. This study conducted a Delphi study of expert opinions, as well as a national survey of potential consumers (N = 1020), to provide critical insights into the potential barriers to implementing intergenerational practice programs. Results revealed that 71.3% of potential consumers would participate in intergenerational practice programs if they were available and experts agreed that the program was of benefit to both populations. However, there were shared concerns regarding the transport, safety, and outcomes of the program for participants. Based on our findings we offer several policy considerations in the implementation of intergenerational programs.
Pollution, Ecological Risk and Source Identification of Heavy Metals in Sediments from the Huafei River in the Eastern Suburbs of Kaifeng, China
Authors: Jin Bingyan , Wang Jinling , Lou Wei , Wang Liren , Xu Jinlong , Pan Yanfang , Peng Jianbiao , Liu Dexin
Published: September 2022

Rivers in urban environments are significant components of their ecosystems but remain under threat of pollution from unchecked discharges of industrial sewage and domestic wastewater. Such river pollution, particularly over the longer term involving heavy metals, is an issue of worldwide concern regarding risks to the ecological environment and human health. In this study, we investigate the long-term pollution characteristics of the Huafei River, an important urban river in Kaifeng, China. River sedimentary samples were analyzed, assessing the degree and ecological risk of heavy metal pollution using the geo-accumulation index and potential ecological risk index methods, whilst Pearson’s correlation, principal component and cluster analyses were used to identify the sources of pollution. The results show that heavy metal concentrations are significantly higher than their corresponding fluvo-aquic soil background values in China, and the geo-accumulation indexes indicate that of the eight heavy metals identified, Hg is most prevalent, followed in sequence by Cd > Zn > Cu > Pb > Ni > As > Cr. The potential ecological risk index of the Huafei River is very high, with the potential ecological risk intensity highest in the midstream and downstream sections, where it is recommended that pollution control is carried out, especially concerning Hg and Cd. Long-term sequence analysis indicates that Cu and Pb dropped sharply from 1998 to 2017, but rebounded in 2019, and that Zn shows a continuous decreasing trend. Four main sources for the heavy metal contaminants were identified: Cr, Cu, Ni, Pb, Zn and Hg derived mainly from industrial activities, traffic sources and natural sources; Cd originated mainly from industrial and agricultural activities; whilst As was mainly associated with industrial activities. Thus, special attention should be paid to Hg and Cd, and measures must be taken to prevent further anthropogenic influence on heavy metal pollution.
Municipal Wastewater Connection for Water Crisis and Jaundice Outbreaks in Shimla City: Present Findings and Future Solutions
Authors: Rathour Ranju Kumari , Sakhuja Deepak , Bhatt Arvind Kumar , Bhatia Ravi Kant
Published: September 2022

The felicitous tourist destination “Hills Queen” and the capital city of Himachal Pradesh, an enticing state in the Himalayan region, are met with water crisis every year and jaundice outbreaks occasionally. In 2016, there was a severe jaundice outbreak in Shimla city. In a contemporaneous investigation, we attempted to trace out the possible reason for these crises in Shimla. Samples were collected month wise from different water-supply sources and their physicochemical and microbial loads were analyzed. The microbiological examination found a totally excessive microbial load (1.064 × 109 cfu/mL on common) throughout the year with a maximum (>1.98 × 1010 cfu/mL) in the wet season and minimum (>3.00 × 107 cfu/mL) in the winter. Biochemical and morphological evaluation confirmed that most of the water resources reported a high number of coliforms and Gram-negative microorganisms due to sewage-water infiltration. These microorganisms in the water are responsible for the liver infection that ultimately causes jaundice. For safe and potable water, infiltration of municipal wastewater must be prevented at any cost. Scientific disposal of wastewater and purification of uncooked water have to be conducted earlier than consumption or use for different domestic functions, to avoid water crises and fetal ailment outbreaks in the near future.
Is Physical Activity an Effective Factor for Modulating Pressure Pain Threshold and Pain Tolerance after Cardiovascular Incidents?
Authors: Leźnicka Katarzyna , Pawlak Maciej , Maciejewska-Skrendo Agnieszka , Buczny Jacek , Wojtkowska Anna , Pawlus Grzegorz , Machoy-Mokrzyńska Anna , Jażdżewska Aleksandra
Published: September 2022

The purpose of this study was to investigate whether regular physical activity can alter the pressure pain threshold, pain tolerance, and subjective pain perception in individuals who have experienced a cardiovascular event. The study involved 85 individuals aged 37 to 84 years (M = 65.36) who qualified for outpatient cardiac rehabilitation, which consisted of 24 physical training sessions. The patients were all tested twice: on the first and last day of the outpatient cardiac rehabilitation program. Assessments of the pressure pain threshold and pain tolerance were performed with an algometer. To assess the pain coping strategies, the Pain Coping Strategies Questionnaire (CSQ) and parenting styles were measured retrospectively with subjective survey questions. The main results of the study showed that patients achieved significantly higher pressure pain thresholds after a physical training cycle (ps < 0.05, η2 = 0.05–0.14), but found no differences in the pain tolerance (ps > 0.05). A lower preference for the better pain coping strategy explanation (ß = −0.42, p = 0.013) and growing up in a family with a less neglectful atmosphere (ß = −0.35, p = 0.008) were associated with increased pressure pain threshold after physical training. The results suggest that physical activity is an important factor in modulating the pressure pain threshold.
Self-Assessment of Health Professionals’ Cultural Competence: Knowledge, Skills, and Mental Health Concepts for Optimal Health Care
Authors: Argyriadis Alexandros , Patelarou Evridiki , Paoullis Panagiotis , Patelarou Athina , Dimitrakopoulos Ioannis , Zisi Vasiliki , Northway Ruth , Gourni Maritsa , Asimakopoulou Evanthia , Katsarou Dimitra , Argyriadi Agathi
Published: September 2022

Current research often refers to cultural competence to improve health care delivery. In addition, it focuses on the cultural uniqueness of each health service user for optimal personalized care. This study aimed to collect self-assessment data from health professionals regarding their cultural competence and to identify their development needs. A mixed methods design was adopted using the Cultural Competence Self-assessment Checklist of the Central Vancouver Island Multicultural Society. This was translated into Greek, validated, and then shared with health professionals in Cyprus. Subsequently, a semi-structured interview guide was designed and utilized. This was structured in exactly the same question categories as the questionnaire. Data collection took place between October 2021 and May 2022, and convenience sampling was used to recruit 499 health scientists in Cyprus. The sample comprised doctors, nurses, psychologists, midwives, social workers, and physiotherapists. Subsequently, 62 interviews were conducted with participants from the same specialties. The results showed that (compared to other health professionals) nurses and psychologists are more sensitive to issues of cultural competence. It would appear that the more socially oriented sciences had better-prepared healthcare staff to manage diversity in context. However, there is a gap between knowledge and skills when comparing doctors to nurses; they seem to be more skilled and willing to intervene actively in cases of racist behavior or problem-solving. In conclusion, participants identified the importance of their cultural competence; they also realized the importance of optimal planning of personalized health care. There is a significant need for continuous and specialized cultural competence training for all health professions.
Post-Adoption Help-Seeking in Portugal: A Comprehensive Study on Parental Difficulties and Help-Seeking Behaviors and Perceptions
Authors: Alves Stephanie , Chorão Ana Luz , Caetano Bárbara , Henriques Margarida Rangel , Pastor Isabel , Pires Raquel
Published: September 2022

Effective psychological parenting interventions delivered to adoptive parents may prevent serious adjustment difficulties and promote a healthy functioning; however, less is known about adoptive parents’ specific parental difficulties and help-seeking behaviors and perceptions, the understanding of which is deemed necessary to design well-informed interventions. This study aimed to describe parental difficulties, help-seeking behaviors, satisfaction with, and perceived barriers to seek, professional help, and acceptability of psychological parenting interventions among Portuguese adoptive parents. Comparisons with biological parents (Study 1) and between adoptive parents that requested adoption-specialized and non-specialized support (i.e., adoption-specialized vs. non-specialized help-seekers) (Study 2) were explored. A cross-sectional online survey was conducted. Participants were 471 adoptive and 552 biological parents of children aged under 18 years who were recruited through schools, adoption agencies, and social networks. They completed measures assessing parental difficulties, help-seeking behaviors, satisfaction with, and perceived barriers to seek, professional help, and acceptability of psychological parenting interventions. Comparison tests between the study groups, Pearson’s correlations, analyses of covariance (ANCOVA) and multivariate logistic regressions (MLR) were performed. Parents’ well-being and normative parenting challenges were the most frequent difficulties in both groups, but only associated with adoptive parents’ help-seeking. Although difficulties related to a child’s problems/parent–child relationship were more frequent among adoptive parents, adoption-related difficulties were rarely reported. Adoptive parents sought professional help more frequently, regardless of parental difficulties. Knowledge-related barriers to seeking help were the most frequent among adoptive parents. Adoption non-specialized help was less satisfactory. Acceptability of psychological parenting interventions was high, but dependent on parental difficulties. Implications for post-adoption services’ development are discussed.
Latent Profile Analysis of Children’s Moral Character and the Classing Effect on Bullying in Rural China
Authors: Zhang Ruiping , Gao Linlin , Cheng Lan , Ren Ping
Published: September 2022

Moral character is the key component of positive youth development. However, few studies have examined children’s moral character and the association with bullying and bullied behavior. Guided by the framework of positive psychology, this study aimed to investigate the association of moral character with bullying and bullied behavior among children in rural China and whether the association differed between left-behind children (LBC) and non-left-behind children (NLBC). A total of 723 children (aged 11–16 years) in rural China completed standard questionnaires that contained six specific character traits and bullying/bullied behavior. Latent profile analysis revealed that children’s moral character was divided into three classes (i.e., low-character class, average-character class, and high-character class). Compared with children in low-character and average-character classes, children in the high-character class had the lowest bullying and bullied behavior. Children in the low-character class were those at greater risk of bullied behavior. The association of the latent character classes with bullied behavior differed between LBC and NLBC. These findings highlight the urgent need for character-based and targeted interventions to prevent children’s bullying and bullied behavior.