bluuebunny/crossref_metadata_2025 huggingface dataset:
Treatment of unipolar affective disorders in pregnant women – benefits and risks
Authors: Pałuchowska Julia , Szymkowicz Anna , Rosołowska-Żak Sara M. , Sambura Maria , Paschke Patrycja , Miczek Igor P.
Published: August 2024

Zaburzenia psychiczne są coraz częstszą jednostką chorobową w społeczeństwie na całym świecie, w znacznym stopniu dotykają również kobiety w ciąży. Według najnowszych badań na depresję cierpi w Polsce 1,5 mln osób i aż 350 mln ludzi na świecie. Ustalono również, że problem dotyczy aż 10,5% kobiet w całej Europie. Zwiększone ryzyko zachorowania na zaburzenia afektywne odnotowuje się w grupie wiekowej między 18 a 44 rokiem życia, czyli populacji kobiet w wieku rozrodczym. Środowisko medyczne stoi przed dylematem wdrożenia leczenia, które zapewni bezpieczeństwo dziecka podczas przyjmowania leków, a także bierze pod uwagę konsekwencje przerwania leczenia związane z efektem odstawienia substancji psychotropowych i możliwością nawrotu objawów chorobowych u kobiet. Celem pracy był przegląd i podsumowanie metod leczenia zaburzeń depresyjnych u kobiet w ciąży, jak również ocena korzyści i ryzyka związanych z podjęciem różnych terapii leczniczych.
Dokonano przeglądu publikacji naukowych opublikowanych w językach angielskim i polskim w bazach PubMed i Google Scholar. Posłużono się takimi słowami kluczowymi jak „depression” oraz „pregnancy”. Leczenie zaburzeń depresyjnych u kobiet w ciąży jest nadal tematem spornym i wymaga indywidualnego podejścia do każdej pacjentki. W trakcie terapii należy rozważyć ewentualne korzyści wynikające z leczenia farmakologicznego, które niesie za sobą ryzyko powikłań u płodu, oraz wybór mniej inwazyjnych metod niefarmakologicznych. Proces diagnostyczny i wybór dalszego postępowania powinny również obejmować potencjalne ryzyko związane z nieleczeniem choroby afektywnej jednobiegunowej u ciężarnych.

Materiały i metody:

Przeprowadziliśmy przegląd publikacji naukowych opublikowanych języku angielskim i polskim w bazach PubMed i Google Scholar. Posługiwaliśmy się słowami kluczowymi takimi jak „depression” oraz „pregnancy”

Wnioski:

Leczenie zaburzeń depresyjnych u kobiet w ciąży jest nadal tematem spornym i wymaga indywidualnego podejścia do każdej pacjentki. W trakcie terapii należy rozważyć ewentualne korzyści leczenia farmakologicznego, które niesie za sobą ryzyko powikłań u płodu oraz wybór mniej inwazyjnych metod niefarmakologicznych. Proces diagnostyczny i wybór dalszego postępowania powinien również obejmować potencjalne ryzyko związane z nieleczeniem choroby afektywnej jednobiegunowej u ciężarnych.
Breed and Reproductive Status Effects on Some Blood Parameters Dryland Goats (Algeria)
Authors: Belkacem Lilia , Rouabah Zahra , Allaoui Assia , Bachtarzi Karina , Belkadi Souhila , Safsaf Boubakeur , Tlidjane Madjid
Published: August 2024

Background: The Damascus breed, known for its prolificacy and milking ability, is recently imported in Algeria. The current investigation aimed to study the effects of physiological status on blood progesterone and some biochemical parameters in Shami goats and their crosses with local breeds in arid conditions of Algeria. Methods: Ten female goats, aged 1.5 to 3 years, were divided into two equal groups: Damascus and Crossbred (Damascus × Arbia). Does were estrus synchronized and naturally mated. Blood samples were collected before intravaginal sponge insertion (non-pregnant), in early (30 days after sponge removal), mid (90 days), late pregnancy (130 days) and 30 days after kidding. Result: The results showed a significant effect of the reproductive stage on progesterone levels in both groups, on glycemia and cholesterolemia in Crossbred does (p less than 0.05) and uremia in the Damascus group. Concentrations of triglycerides and creatinine revealed no significant difference between physiological phases in both groups. Breed effect was detected in early and mid-pregnancy for P4. Changes in assessed parameters of both groups reflect the goat’s adaptation to the increased requirement of pregnancy and lactation in the arid conditions of Algeria.
Effect of Garlic Extract (Allium sativum) on Hematological and Clinical Chemistry Parameters of Laying Quail
Authors: Hidayatik Nanik , Yuliani Gandul Atik , Agustono Bodhi , Kristianingtyas Luviana , Novianti Arindita Niatazya , Hestianah Eka pramyrtha , Khairullah Aswin Rafif
Published: August 2024

The purpose of this study was to determine the effect of garlic extract (Allium sativum) in drinking water on the hematological profile of laying quail. In a completely randomized design (CRD), one hundred and twenty laying quail were randomly allocated to four treatments, with six replicates of five quail each. The treatment drink water are as follows, the control P0 (0%), 1% garlic extract (P1), 2% garlic extract (P2) and 4% garic extract (P3). Feed and water were supplied ad libitum. The parameters measure were; the number of erythrocytes, hemoglobin, hematocrit, lymphocytes, monocytes and granulocytes. Blood samples from each quail were collected to analyze the hematological parameters. The result of hematological data showed that supplementation of garlic extract in drinking water had a significant effect (P less than 0.05) on hemoglobin levels, but did not have a significant effect (P greater than 0.05) on erythrocyte, hematocrit, lymphocyte, monocyte and granulocyte levels. Meanwhile, the hemoglobin levels themselves showed that treatment P2 (2%) had a significant effect compared to other treatments. Based on clinical chemistry it shows that adding garlic extract with concentrations of 0% (control), 1%, 2% and 4% to drinking water does not have a significant effect (P greater than 0.05) on Aspartate transamnase (AST), Alanine aminotransferase (ALT), total cholesterol, triglycerides, BUN, creatinine and glucose. It can be concluded that the best treatment is giving 2% extract in drinking water which is able to improve the haematological profile of quail in terms of increasing hemoglobin levels.
Optimizing the Supplementation of Calcium and Phosphorus in the Diets of Asian Seabass (Lates calcarifer) in Freshwater based Recirculating Aquaculture System
Authors: Moses T.L.S. Samuel , Ahilan B. , Chidambaram P. , Felix N. , Jayakumar N.
Published: August 2024

Background: Calcium and phosphorus are important mineral nutrients for all energy-producing cellular and metabolic pathways. Fish obtain Ca and P from their feed because of the low level of calcium and phosphorus in the freshwater especially in the RAS system. This study was investigated to evaluate the growth characteristics, survival rate, calcium and phosphorus composition and haematological and biochemical parameters of Asian Seabass (Lates calcarifer) under the influence of varied combinations of calcium and phosphorus in the formulated sinking feed. Methods: The experiment was carried out with Asian Seabass fingerlings, each with an initial average weight of 2.00±0.15 g which were randomly distributed in 54 Nos. of PE tanks with a volume of 500 Litres @ 30 Nos./tank. The experiment duration was 60 days and was carried out in a 6×3 factorial design. The fishes were fed with a sinking pellet diet containing calcium Ca 0.0, Ca 0.5% and Ca 1.0% and phosphorus P 0.0, P 0.5%, P 1.0%, P 1.5%, P 2.0% and P 2.5% and all the possible combinations of above percentages of calcium and phosphorus in the experimental diets. Result: The growth characteristics and survival rates were significantly higher in 1% of calcium and phosphorus-contained feed, the calcium and phosphorus composition and haematological and biochemical parameters also confirmed the experimental results. Our study outcome was useful for formulating a calcium and phosphorus-incorporated sinking feed to Asian Seabass for better growth in the recirculating aquaculture system.
Influence of Planting Methods on Growth, Yield and Storage of Onion (Allium cepa L.) var. Bhima Shakti
Authors: Jeevitha D. , Chimmalagi Umesh , Adishesha K. , Hosamani Goutam B. , Vinay T.V. , Dharmatti P.R.
Published: August 2024

Background: Successful crop production in any crop depends on the good agronomic practices. Being a commercial crop, onion needs good attention during the crop growth stages, most of the times, in onion cultivation farmers follow broadcasting method which leads to the wastage of seeds, seedling mortality and poor germination and it will affect the total yield and productivity. Methods: To identify the best planting method an investigation on performance of seed drill versus transplanted onion was conducted at University of Agricultural Sciences, Main Agriculture Research Station, Dharwad. Result: Results indicated that, T3- (Transplanting) performed superior for all the vegetative and yield parameters studied. Plant height 55.57 cm, leaf number (7.86, 8.29 and 8.08 in pooled), Leaf width (1.03 cm, 0.99 cm pooled 1.01 cm). Total yield: (21.97 t/ha, 22.05 t/ha and 22.01 t/ha), marketable yield (20.74 t/ha, 20.95 t/ha and 20.85 t/ha), bulb weight (64.00 g, 53.00 g and 53.90 g in pooled analysis). From this, it can be concluded that transplanting of onion was better compared to other methods.
Comparative Metabolomics Analysis of 3 New Potato Varieties against the Atlantic Cultivar; Bioinformatics based Experimental Study
Authors: Zhao Liang , Hu Fang , Keremu Nasirula , Cheng Yanjun , He Liming , Yu Hui
Published: August 2024

Background: Varietal differences in metabolite composition play a crucial role in determining agronomic traits, nutritional quality and stress resilience in Solanum tuberosum. Methods: Three potatoes varieties; Longshu 7, Longshu 10 and Longshu 14 were selected and bred by the at the Potato Research Institute of Gansu Academy of Agricultural Sciences between December 2021 to December 2023. Thereafter, comparative metabolomics analysis of three new potato varieties (LS7, LS10 and LS14) was undertaken against the well-established Atlantic cultivar. We employed a bioinformatics-based experimental approach to analyze the metabolomic data obtained from the three new potato varieties (LS7, LS10 and LS14) and the Atlantic cultivar. Metabolite profiling was performed using high-throughput liquid chromatography-mass spectrometry (LC-MS) techniques. Differential metabolite analysis and pathway enrichment analysis were conducted to identify significant metabolic differences and enriched pathways among the varieties. Result: Results revealed substantial differences in metabolite composition and pathway enrichment between the new potato varieties and the Atlantic cultivar. Metabolites involved in diverse metabolic pathways, including glucoside and hydroxyproline in LS7, kaempferol and ascorbic acid in LS10 and phenyl-butyryl-glutamine and ascorbic acid in LS14, exhibited significant upregulation or downregulation compared to the Atlantic cultivar. Pathway enrichment analysis highlighted the prominence of ABC transporters across all comparisons, suggesting their universal role in mediating cellular processes and stress responses in potato varieties. In conclusion, these findings contribute to our understanding of potato metabolism and pave the way for the development of novel breeding approaches to meet the evolving demands of global agriculture and food security.
“Mirroring” the World Versus “World-Making”: The Crisis of Ethics in Indian Mental Health Systems
Authors: Kottai Sudarshan R.
Published: August 2024

In the context of neoliberalism and increasing globalization, technocratization, and scientification of mental health care, people suffering from socio-politico-economic problems ranging from poverty to structural violence are often transmogrified into “patients” with mental health problems to be “treated” with psychopharmaceuticals and individualized psychological therapies. Drawing from three socio-political issues India witnessed in the past 3 years, concerning three marginalized sections, namely, farmers, LGBTQIA+ people, and migrant workers, I illustrate the silence of mainstream mental health disciplines in India on sheer instances of structural violence and social suffering. Deflection of attention from human rights violations by mainstream mental health systems raises critical questions about the ethics and politics of mental health disciplines. The social, political, and material contexts that are central to lived experiences are almost always unaccounted in mental health academia, research, and practice. Engaging people with lived experiences advances equity by breaking down power dynamics, establishing collaborative decision-making, and improving equitable outcomes. Thus, knowledge production in mental health becomes irrelevant to political action and transformative policies that are crucial for positive mental health outcomes. By ignoring and thus implicitly sanctioning discriminatory, exploitive neoliberal architecture, mental health systems maintain the very upstream factors that cultivate and sustain mental distress. In this way, mainstream mental health practice in India fails to undertakeworld-making, raising deeper questions in public mental health ethics.
Síntese e Caracterização Espectroscópica do Dióxido de Silício (SiO2) Obtido a partir da Calcinação do Bagaço da Cana-de-Açúcar
Authors: E. S. Reis Maria , V. A. Martins Marccus , G. Rodrigues Bianca , P. C. Oliveira Jocélia
Published: August 2024

Esse trabalho reportou a obtenção e caracterização espectroscópica da sílica (SiO2) a partir da biomassa do bagaço da cana-de-açúcar. Inicialmente, otimizou-se o tratamento químico em meio básico para a diminuição do caráter orgânico das fibras. Após essa etapa as fibras foram calcinadas a 800 °C para obtenção do SiO2. Os espectros de infravermelho (FTIR) revelaram o desaparecimento de ligações químicas após o tratamento na solução de NaOH (0,5 mol.L-1) e a presença de ligações pertencentes aos grupos de silicatos (Si-O-Si) nas cinzas. Os espectros de Difração de Raios X confirmaram a obtenção de sílica cristalina com predominância da fase quartzo.
Influência das Propriedades Dielétricas de Solventes nas Características Estruturais e Ópticas da Molécula HPMP
Authors: M. Silva Poliana , Cristine Fernandes Daphne , V. B. Soares João , C. de Castro Jhenyfer , M. O. Junior Euripedes , Valverde Clodoaldo
Published: August 2024

A interação entre as moléculas de solvente e soluto pode alterar a estrutura molecular e as propriedades ópticas do meio. Este estudo analisa as propriedades geométricas e elétricas de um derivado de chalcona, 1-{4-hydroxy-3-[(pyrrolidin-1yl)methyl]phenyl}-3phenylprop- 2-en-1one (HPMP), usando dados de cristalografia de raios-x. Para as propriedades geométricas, nove solventes foram examinados com um modelo de solvatação contínua polarizável, aplicando o funcional B3LYP e o conjunto de base 6-311++G(d,p) no programa Mercury 3.9, visando determinar valores de distâncias máximas, dimensões de ligações, ângulos diedrais e desvio quadrático médio. As propriedades elétricas, como o momento de dipolo e a polarizabilidade, foram calculadas usando métodos quânticos ab initio.
Evaluasi Kekuatan Struktur Jembatan Rasuk Plat BH 1385 KM 347 + 431 Purwokerto Terhadap Beban Statis Lokomotif CC 206
Authors: Ferdiansyah Fajryn , Kurniawan Muhammad Adib , Imron Nanda Ahda
Published: August 2024

This research analyzes the strength of the upper structure of plate girders BH 1385 KM 347 + 431 between Karanggandul - Purwokerto on the downstream route of Cirebon-Kroya. The analysis includes assessing its capacity to withstand the locomotive series CC 206 load, considering its construction history since 1917 and the planned load in 1911. The bridge's steel profile was measured for technical drawings involving the steel profile's inertia with hole elongation. Working loads were manually analyzed and compared with SAP 2000 application results. The analysis indicates a deflection of 0.717 cm manually and 0.624 cm with SAP 2000, with bending stresses of 0.903 T/cm2 and 0.592 T/cm2, respectively. Both results remain below the allowable deflection limit of 1.35 cm and the stress limit of 1.300 T/cm2, confirming the bridge's current safety. These calculations serve as a reference for the bridge's safety.
ABSTRAK
Penelitian ini menganalisis kekuatan struktur bagian atas jembatan baja tipe rasuk plat BH 1385 KM 347 + 431 di antara Karanggandul - Purwokerto, jalur hilir Cirebon-Kroya. Analisis mencakup kemampuan jembatan menahan beban lokomotif seri CC 206 dengan mempertimbangkan sejarah konstruksi sejak 1917 dengan rencana muatan rencana tahun 1911. Pengukuran profil baja jembatan dilakukan untuk gambar teknis dan perhitungan melibatkan inersia profil baja dengan perlemahan lubang keling. Beban-beban yang bekerja kemudian dianalisis secara manual dan dibandingkan dengan hasil aplikasi SAP 2000. Hasil menunjukkan lendutan jembatan sebesar 0,717 cm secara manual dan 0,624 cm dengan SAP 2000, serta tegangan lentur masing-masing 0,903 T/cm2 dan 0,592 T/cm2. Kedua hasil tetap di bawah izin maksimum lendutan 1,35 cm dan tegangan 1,300 T/cm2, menunjukkan jembatan masih aman menahan beban saat ini. Hasil perhitungan ini dapat digunakan sebagai acuan keamanan jembatan.
Development of Evaluation Indicators for Logistic Transportation System with Triple Bottom Line Approach: Jakarta Study Case
Authors: Julian Muhammad Hafiz Risat , Nahry Nahry
Published: August 2024

Jakarta has significant problems related to logistics transportation, including congestion, environmental pollution, and the negative impact of operating overloaded trucks. To overcome these externalities, it is necessary to have an urban logistics system and planning cycle that considers the concept of sustainability. This study aims to propose an arrangement of indicators as a tool for evaluating the urban logistics transportation system. The research was carried out through a literature study process, identification of the long list of indicators and selection criteria, independent selection, surveys and interviews, ranking with the VIKOR Method, and validation with expert considerations. A final set of indicators was produced, namely ten indicators, divided into economic, social, and environmental aspects, for evaluating the sustainability of the city's logistics transportation system. This research is helpful as input in developing a set of indicators for evaluating the logistics transportation system in urban areas, especially in Jakarta Capital Special Region.
ABSTRAK
Jakarta memiliki permasalahan signifikan terkait transportasi logistik, antara lain kemacetan, pencemaran lingkungan, dan dampak negatif pengoperasian truk dengan muatan berlebih. Untuk mengatasi eksternalitas tersebut, diperlukan sistem logistik perkotaan dan siklus perencanaan yang mempertimbangkan konsep keberlanjutan. Penelitian ini bertujuan untuk mengusulkan suatu susunan indikator sebagai alat bantu evaluasi sistem transportasi logistik perkotaan. Penelitian dilakukan melalui proses studi literatur, identifikasi Long-list indikator dan kriteria seleksi, seleksi mandiri, survei dan wawancara, pemeringkatan dengan Metode VIKOR, dan validasi dengan pertimbangan para ahli. Dihasilkan seperangkat indikator akhir, yaitu sepuluh indikator yang terbagi dalam aspek ekonomi, sosial, dan lingkungan untuk menilai keberlanjutan sistem transportasi logistik kota. Penelitian ini bermanfaat sebagai masukan dalam mengembangkan seperangkat indikator untuk mengevaluasi sistem transportasi logistik di perkotaan, khususnya di Daerah Khusus Ibukota Jakarta.
The Critical Discourse Analysis of Moral Values in a Senior High School English Textbook Published by Indonesian Ministry of Educational Culture
Authors: Hidayatullah Ikmal , Setyono Budi , Ariyanto Sugeng
Published: August 2024

The effect of globalization in all sectors of life will impact on the moral degradation of the Indonesian students. It is due to the fact that it is easy for students to imitate cultural behaviors from other countries through social media that are difficult to be controlled by parents and teachers. School children who are still immature in mind may easily adopt the fast spread of information from different parts of the world regardless of whether or not they are appropriate with the Indonesian culture. Culturally, what is considered good behaviors in one country may not be accepted in other countries or vice versa. Therefore, the inclusion of moral education (character education) in Indonesia is crucial to avoid students’ misconception of moral values and to direct students’ behaviors in appropriate ways.
INCREASED INCIDENTS OF STUNTING IN MAJENE DISTRICT WEST SULAWESI
Authors: Masriadi  , Mahmud Nur Ulmy , Javid Nazli , Wulandari Sri , Fachrin Suharni A.
Published: August 2024

Introduction: Stunting is a condition of chronic malnutrition caused by malnutrition that occurs over a long period of time, caused by food supply that does not match the nutritional needs of children. Developmental delay occurs when the child is still in the mother's womb and appears when the child is two years old. There is prevalence of stunted toddlers in 6 districts in West Sulawesi, namely Majene District (40.6%), Polewali Mandar District (39.3%), Mamasa (38.6%), Mamuju (33.8%), Central Mamuju (28.1%), and Install Wood  (25.8%). Aims: Analysis of risk factors for stunting in Majene district. Method: This type of study is an observational study with a case-control study design. The number of toddlers is 418 toddlers. The sample for this study included 112 toddlers aged 0-59 months. The sampling technique is by means of proportional sampling. Results: the study shows that Kadarzi (OR 17.274), self-efficacy (OR 3.240), and socio-culture are risk factors for increased stunting in Majene District, KAP variable (OR 0.321) is a protective factor against stunting in Majene District. Conclusion: Kadarzi, self-efficacy, and socio-cultural variables are risk factors for stunting in Majene Regency. It is hoped that mothers will pay more attention to their toddler's nutritional intake from birth, especially on exclusive breastfeeding, MP-ASI, and various foods, and routinely bring their toddlers to the posyandu every month to find out their toddler's nutritional growth and development.
THE USE OF SOCIAL MEDIA AS A SOURCE OF COMPLEMENTARY FEEDING INFORMATION FOR MOTHERS
Authors: Hanindita Meta Herdiana , Widjaja Nur Aisiyah , Hidayati Siti Nurul , Irawan Roedi , Hidayat Boerhan
Published: August 2024

Introduction: In the digital age, social media (SM) has undeniably transformed the way parents access information, including complementary feeding (CF) practices. Approximately 57.1% mothers in Indonesia obtained information about CF from the internet, ranging from parenting forums to social media platforms like Instagram. Aims: To explore the use of SM as source of CF information among mothers in Indonesia. Method: Exploratory cross-sectional study was conducted in 1631 mothers of children 0-23 months in May 2023, using an online questionnaire. The analysis of the data was conducted using the statistical software SPSS 21.0 Results: Of all the subjects, the largest group consisted of those aged 26-30 years. A majority had a high level of education, had SM, and spent 30-60 minutes (59.2%) searching for CF information. Full-time mothers were more influenced by SM (p=0.043). A notable distinction existed in the choice of social media based on the level of education. The higher the education, the more Instagram was used, while the lower the education, the more TikTok was used (mothers p=0.000; fathers p=0.002). The higher the education, the more information sources were sorted (mothers p=0.014; fathers p=0.000), and the more the educational background of the informant was considered (mothers p=0.000; fathers p=0.000). Conclusion: Mothers seek CF information from SM because it is faster, easier and convenient. However, it is often not evidence-based, and the amount of conflicting information confuses parents. Health efforts with a promotive approach that are evidence-based, understandable and applicable are needed and can be carried out through SM.
MOTHER’S HEALTH LITERACY WITH STUNTING INCIDENCE OF TODDLERS IN JEMBER
Authors: Mazida Zulfa , Noveyani Adistha Eka , Prasetyowati Irma
Published: August 2024

Introduction: Mothers have a role in caring for and fulfilling toddler nutrition which is very important to prevent stunting in toddlers. Mothers’ skills in carrying out their roles are influenced by mothers’  knowledge through health literacy, namely the capability to access, assess, and process health information. Prevalence of stunting in East Java was 26.8% in 2019, exceeding the limit set by WHO. Jember is the second area contributing to the largest prevalence of stunting in East Java. Aims: This study aimed to analyze the relationship of mothers’ health literacy with stunting incidence of toddlers. Methods: This study used a case control design. The respondents were mothers with stunting toddlers (n=51) and mothers with non-stunted toddlers (n=51). The secondary data sources were the stunting data of the Kalisat Primary Healthcare in February 2022 and the primary data sources were the results of interviews used the HLS-EU-16 Indonesia Questionnaire. Data analysis used chi-square test. Results: There was a relationship between mothers’ health literacy and  stunting incidence of toddlers with a p-value of  0.001 (p-value < 0.05 so that the two variables have a significant relationship. Conclusion: Mothers’ health literacy has a strong association with stunting incidence of toddlers.
Pemberian Edukasi untuk Meningkatkan Pengetahuan Siswa dalam Pelaksanaan Bantuan hidup Dasar
Authors: Siwi Adiratna Sekar , Kurniawan Wasis Eko , Hidayat Arif Imam
Published: August 2024

Keadaan gawat darurat merupakan keadaan klinis pasien membutuhkan tindakan medis segera untuk menyelamatkan nyawa dan kecacatan berikutnya. Kondisi jantung berhenti berdenyut merupakan salah satu kasus kegawatdaruratan. Kasus henti jantung sering terjadi secara tiba-tiba tanpa gejala awal yang dapat terjadi dimana saja dan kapan saja. Hal yang perlu dipahami oleh semua profesi kesehatan termasuk orang awam yaitu konsep dasar gawat darurat. Ada tiga konsep dasar gawat darurat, pertama adalah kecepatan waktu saat pertama korban ditemukan, kedua ketepatan dalam memberikan pertolongan pertama, dan ketiga adalah pertolongan oleh petugas kesehatan yang kompeten. Pemahaman yang utuh tentang konsep gawat darurat, sehingga angka kematian dan kecacatan dapat diminimalisir. Salah satu upaya pertolongan pertama yang perlu dimiliki adalah Basic Life Support (BLS) atau Bantuan Hidup Dasar (BHD). Penyuluhan dan pelatihan merupakan upaya yang penting dilakukan untuk meningkatkan pengetahuan dan keterampilan masyarakat awam dalam memberikan pertolongan pre hospital. Penyuluhan dan pelatihan ini baik diberikan sejak usia muda untuk menciptakan generasi muda yang berkompeten dalam mengaplikasikan serta mensosialisasikan cara untuk memberikan pertolongan pre hospital. Metode yang dilakukan pada kegiatan ini adalah ceramah dan diskusi. Peserta pengabdian ini adalah anggota pengurus BEM serta mahasiswa tingkat awal sejumlah 40 orang. Diketahui tingkat pemahaman tentang BHD sebelum pengabdian sebagian besar dalam kategori pengetahuan baik (78%) dan setelah dilakukan tindakan sebagian besar dalam kategori pengetahuan baik (95%). Pengabdian kepada masyarakat ini telah berhasil mencapai tujuan utama yaitu meningkatkan pengetahuan siswa tentang pelaksanaan Bantuan Hidup Dasar sebagai upaya pertama dalam menyelamatkan korban tidak sadar.
OPTIMALISASI PERAN SERTA MASYARAKAT DALAM PELAYANAN KESEHATAN JIWA
Authors: Zaini Mad , Widada Wahyudi , Dwi Cahya Ningrum Dian , Isnaini Agustina Intan
Published: August 2024

Prevalensi masalah kesehatan jiwa di Indonesia terus mengalami peningkatan. Hasil Riset Kesehatan Dasar Tahun 2018 menunjukkan lebih dari 19 juta penduduk berusia lebih dari 15 tahun mengalami masalah kesehatan psikososial, dan lebih dari 12 juta penduduk berusia lebih dari 15 tahun mengalami depresi. Desa Sukorambi merupakan wilayah transisi perkotaan di Kabupaten jember sehingga memungkinkan masuknya budaya dari luar daerah Jember, hal ini disebabkan banyaknya pendatang baru di wilayah tersebut. Selain itu sebagian masyarakat Desa Sukorambi adalah masyarakat dengan mata pencaharian sebagai petani atau berkebun. Metode yang dipergunakan dalam kegiatan ini adalah pelatihan kesehatan jiwa dan deteksi masalah kesehatan jiwa di masyarakat. Peserta yang ikut dalam kegiatan ini sebanyak 40 orang. Dalam kegiatan ini, seluruh peserta aktif dalam kegiatan pengabdian masyarakat. Pengetahuan peserta tentang masalah kesehatan jiwa di masyarakat juga mengalami penigkatan. Luaran dalam kegiatan ini adalah terbentuknya kader kesehatan jiwa dan laporan hasil kegiatan sebagai data dasar perencanaan intervensi tahap selanjutnya.
Authors: Nurlita Sarah , Setiawati NIna , Kartikasari Aprillia
Published: August 2024

Background: Pregnancy often cause discomfort, including frequent micturition and the risk of hemorrhoids. In pregnant women with hemorrhoids history before pregnancy, hemorrhoids are more susceptible to recurrence. Because these complaints are temporary, non-pharmacological treatment is recommended. A therapy that can overcome these two complaints is Kegel exercises. Kegel exercise is a movement to tighten the pelvic floor muscles which aims to strengthen the urinary tract and muscles in the genitalia and anus area. Health education using demonstration methods and booklet media regarding Kegel exercises, benefits, and prevention of hemorrhoid recurrence. Pre-test and post-test are carried out to determine the client's understanding of the education provided. The client is a 37 years old woman with G4P2A1 H22 Week with complaints of frequent micturition and a history of hemorrhoids before pregnancy.
Results: Clients can demonstrate Kegel exercises independently without instructions and the frequency of micturition is reduced. The client's post test results increased to 80% and the client began to increase healthy behavior by increasing fluid intake.
Conclusion: There is a decrease in the frequency of micturition and an increase in healthy behavior in clients after being given Kegel exercise education.
Authors: Sashikirana Amalda , Upoyo Arif Setyo , Triyanto Endang
Published: August 2024

Hypertension as one of non-transmitted disease with the highest number of sufferers in Indonesia, is frequently causing any complaints on its sufferer such as high blood pressure that did not decrease even though sufferer has taken medicine, heart ponding that could lead to difficulty to sleep. The aim of this research is to find out the effect of foot massage and gamelan music therapy to decrease in blood pressure and heart rate, along with the increase in sleep quality in hypertensive patient. This research use study case approach to a 61 years old female patient. Results of this research shows that there are changes in blood pressure with an average decrease by 10.3 mmHg per day in systolic pressure and average decrease by 4.3 mmHg per day in diastolic pressure. Meanwhile, average decrease of heart rate is about 1.3 beats per minute per day after intervention and average increase of PSQI score by 1.3 point. Conclusion: foot massage and gamelan music therapy can be applied as complementary therapy alongside medication therapy to decrease blood pressure and heart rate, as well as to increase sleep quality in hypertensive patients.
Keyword: blood pressure, foot massage, gamelan music therapy, heart rate, sleep quality
Bell's Theorem Begs the Question
Authors: Christian Joy
Published: August 2024

I demonstrate that Bell's theorem is based on circular reasoning and thus a fundamentally flawed argument. It unjustifiably assumes the additivity of expectation values for dispersion-free states of contextual hidden variable theories for non-commuting observables involved in Bell-test experiments, which is tautologous to assuming the bounds of ±2 on the Bell-CHSH sum of expectation values. Its premises thus assume in a different guise the bounds of ±2 it sets out to prove. Once this oversight is ameliorated from Bell's argument by identifying the impediment that leads to it and local realism is implemented correctly, the bounds on the Bell-CHSH sum of expectation values work out to be ±2√2 instead of ±2, thereby mitigating the conclusion of Bell's theorem. Consequently, what is ruled out by any of the Bell-test experiments is not local realism but the linear additivity of expectation values, which does not hold for non-commuting observables in any hidden variable theories to begin with. I also identify similar oversight in the GHZ variant of Bell's theorem, invalidating its claim of having found an inconsistency in the premisses of the argument by EPR for completing quantum mechanics. Conceptually, the oversight in both Bell's theorem and its GHZ variant traces back to the oversight in von~Neumann's theorem against hidden variable theories identified by Grete Hermann in the 1930s.
Navigating Artificial General Intelligence (AGI): Societal Implications, Ethical Considerations, and Governance Strategies
Authors: Bikkasani Dileesh Chandra
Published: August 2024

Artificial General Intelligence (AGI) represents a pivotal advancement in AI with far- reaching implications across technological, ethical, and societal domains. This paper addresses the following: (1) an in-depth assessment of AGI’s transformative potential across different sectors and its multifaceted implications, including significant financial impacts like workforce disruption, income inequality, productivity gains, and potential systemic risks; (2) an examination of critical ethical considerations, including transparency and accountability, complex ethical dilemmas and societal impact; (3) a detailed analysis of privacy, legal and policy implications, particularly in intellectual property and liability, and (4) a proposed governance framework to ensure responsible AGI development and deployment. Additionally, the paper explores and addresses AGI's political implications, including national security and potential misuse. By analyzing and considering computer science, philosophy, economics, and policy perspectives, we offer a multidisciplinary view of AGI’s challenges and opportunities, advocating for proactive measures to align AGI development with human values and societal interests.
Patients’ Satisfaction after the Treatment of Moderate Sleep Apnea and Nocturnal Bruxism with Botox or/and Thermoformed Occlusal Splints: Preliminary Study
Authors: Rezk Gavrilă Talaat Gabriel , Bechir Anamaria , Nicolau Andrada Camelia , Bechir Edwin Sever
Published: August 2024

The aim of the study was to investigate the effects of Botox injection therapy, with or without wearing thermoformed occlusal splints, in patients with sleep apnea and nocturnal bruxism and to determine their degree of satisfaction after completing the therapy. The selected patients (n = 36, 24 female and 12 male) with sleep apnea and nocturnal bruxism were divided into two groups. The first group of 18 patients (G1) was treated by injecting Botox (Allergan) into the masseter muscle. The 18 patients in the second group (G2) benefited from associated therapy represented by Botox injections in masseter muscle and the wear of thermoformed occlusal splints. Four monitoring sessions were realized: at baseline, at three weeks, at three months, and at six months after the effectuation of treatments. The associated therapy (Botox and thermoformed occlusal splints) presented much better results over time in decreasing the sleep apnea and nocturnal bruxism symptoms than the one represented only by injections with Botox, but Botox injections presented a rapid relief of both disease signs. Patient satisfaction after the applied treatments was very good, but in patients with associated therapy, it was better after six months than in first-group patients.
Second Victims among Austrian Nurses (SeViD-A2 Study)
Authors: Potura Eva , Roesner Hannah , Trifunovic-Koenig Milena , Tsikala Panagiota , Klemm Victoria , Strametz Reinhard
Published: August 2024

Background: The Second Victim Phenomenon (SVP) significantly impacts the well-being of healthcare professionals and patient safety. While SVP has been explored in various healthcare settings, there is limited data on its prevalence and associated factors among nurses in Austria. This study investigates the prevalence, symptomatology, and preferred support measures for SVP among Austrian nurses. Methods: A nationwide, cross-sectional, anonymous online survey was conducted using the SeViD questionnaire (Second Victims in German-speaking Countries), which includes the Big Five Inventory-10 (BFI-10). Statistical analyses included binary logistic regression and multiple linear regression using the bootstrapping, bias-corrected and accelerated (BCa) method based on 5000 bootstrap samples. Results: 928 participants responded to the questionnaire. Among the respondents, 81.58% (744/912) identified as Second Victims (SVs). The primary cause of becoming a SV was aggressive behavior from patients or relatives. Females reported a higher symptom load than males, and higher agreeableness was linked to increased symptom severity. Notably, 92.47% of SVs who sought help preferred support from colleagues, and the most pronounced desire among participants was to process the event for better understanding. Conclusions: The prevalence of SVP among Austrian nurses is alarmingly high, with aggressive behavior identified as a significant trigger. The findings emphasize the necessity for tailored support strategies, including peer support and systematic organizational interventions to mitigate the impact of SVP on nurses and to improve overall patient care. Further research should focus on developing and implementing effective prevention and intervention programs for healthcare professionals in similar settings.
Thermomechanical and Viscoelastic Characterization of Continuous GF/PETG Tape for Extreme Environment Applications
Authors: Colón Quintana José Luis , Tomlinson Scott , Lopez-Anido Roberto A
Published: August 2024

The thermomechanical and viscoelastic properties of a glass fiber polyethylene terephthalate glycol (GF/PETG) continuous unidirectional (UD) tape were investigated using differential scanning calorimetry (DSC), thermo-mechanical analysis (TMA), and dynamic mechanical analysis (DMA). The study identified five operational conditions based on Army Regulation 70-38 Standard. The DSC results revealed a glass transition temperature of 78.0 ± 0.3°C, guiding the selection of temperatures for TMA and DMA tests. TMA provided the coefficient of thermal expansion in three principal directions, consistent with known values for PETG and GF materials. DMA tests, including strain sweep, temperature ramp, frequency sweep, creep, and stress relaxation, defined the linear viscoelastic region and temperature-dependent properties of the material. The frequency sweep indicated an increase in modulus with rising frequency, identifying several natural frequency modes. Creep and stress relaxation tests showed time-dependent behavior, with strain increasing under higher loads and stress decreasing over time for all tested input values. Viscoelastic models fitted to the data yielded R² values of 0.99, demonstrating good agreement. The study successfully measured thermo-mechanical and viscoelastic properties across various conditions, providing insights into how temperature influences the material's mechanical response under extreme conditions.
Is Hydrogen Viable as Alternative Fuel for Heavy-Duty Vehicles Based on Internal Combustion Engines?
Authors: Baldinelli Arianna , Francesconi Marco , Antonelli Marco
Published: August 2024

Hydrogen mobility embodies a promising solution to address the challenges posed by traditional fossil-fuel-based vehicles. The use of hydrogen in small heavy duty road vehicles based on internal combustion engines (ICEs) may be appealing for two fundamental reasons: direct electrification seems less promising in heavy duty transport systems and fuel cell-based hydrogen vehicles implementation may not proceed at the expected pace due to higher investment costs compared to ICEs. On the other hand, hydrogen combustion is gaining attractiveness and relies on robust and cheap technologies, but it is not the only renewable solution. In this framework, this work presents a methodology to assess Weel-to-Whell primary energy consumption and CO2 emissions of small heavy-duty vehicles. The methodology is applied in a real case-study, namely a passenger coach travelling on a 100 km-mission in non-optimized conditions. Therefore, the suitability of hydrogen is compared with standard diesel and other alternative diesel-type fuels (biodiesel and synthetic diesel types). Hydrogen shows competitivity with standard diesel from the point of view of CO2 emission reduction (-29%) while it hides a higher primary energy consumption (+40%). Nonetheless, HVO brings the highest benefits both from the point of view of primary energy consumption and emission reduction, namely -35% and 464-634 kgCO2/100km avoided compared to hydrogen.
A Perception Survey of Lean Management Practices for Safer Off-Site Construction
Authors: Simukonda Wakisa , Emuze Fidelis
Published: August 2024

Lean practice is recognised for having a great potential in promoting safety risk management in offsite construction (OSC). This paper presents results of a study conducted to assess the impact of lean practice in safety risk management in OSC in a developing country. A quantitative approach using survey-based questionnaire was adopted. Lean management practices (LMPs) identified from literature review were empirically tested using a sample survey of 103 OSC contractors. The survey responses were subjected to descriptive and inferential statistics. The top ranked LMPs for safety risk management in OSC included two mistake proofing practices, i.e., use of personal protective equipment (PPE) and use of hazard warning equipment; two last planner system (LPS) practices, i.e., involvement of workers in safety planning and providing necessary working equipment and one first run studies (FRS) practice, i.e., critical analysis of work methods. These LMPs are useful in controlling high consequence safety risks in OSC. Based on evidence found in this study, the paper argues that lean practice can bring great value in the safety risk management in OSC in countries where OSC is transitioning.
Harnessing the Power of ChatGPT in Cardiovascular Medicine: Innovations, Challenges, and Future Directions
Authors: Leon Marc , Ruaengsri Chawannuch , Pelletier Glenn J , Bethencourt Daniel Miguel , Shibata Masafumi , Flores Manuel Quiroz , Shudo Yasuhiro
Published: August 2024

Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality globally, posing significant challenges to public health. The rapid development of artificial intelligence, particularly Large Language Models like ChatGPT, has revolutionized various fields, including cardiovascular medicine. ChatGPT, recognized for its broad applicability, efficiency, and public acceptance, has been integrated into multiple facets of CVD management. This comprehensive review examines the current applications of ChatGPT in cardiovascular medicine, emphasizing its innovative and significant role in enhancing diagnosis and clinical decision-making, improving medical education, and facilitating research and academic communication. Furthermore, the review article addresses the significant challenges associated with ChatGPT and proposes directions for future development to overcome these obstacles and boost its effectiveness. By exploring the vast potential of ChatGPT to meet the needs of the large CVD patient population and the extensive community of cardiovascular professionals, this review aims to provide valuable insights for optimizing its use in cardiovascular medicine, ultimately improving patient outcomes and advancing the field.
Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles in Liver Injury
Authors: Dong Jingjing , Luo Ying , Gao Yingtang
Published: August 2024

Liver injury caused by various factors significantly impacts human health. Stem cell transplantation has potential for enhancing liver functionality, but safety concerns such as immune rejection, tumorigenesis, and the formation of emboli in the lungs remain. Recent studies have shown that stem cells primarily exert their effects through the secretion of extracellular vesicles (EVs). EVs have been shown to play crucial roles in reducing inflammation, preventing cell death, and promoting liver cell proliferation. Additionally, they can function as carriers to deliver targeted drugs to the liver, thereby exerting specific physiological effects. EVs possess several advantages, including structural stability, low immunogenicity, minimal tumorigenicity targeting capabilities, and convenient collection,. Consequently, these factors have garnered significant attention from researchers and are expected to become alternative therapeutic agents to stem cell therapy. This article provides a comprehensive review of the current research progress on the use of stem cell-derived EVs in the treatment of liver injury.
COVID-19 Pandemic Increases the Risk of Anxiety and Depression among Adolescents: A Cross-Sectional Study in Rural West Bengal, India
Authors: Mitra Amal K. , Dutta Sinjita , Mondal Aparajita , Rashid Mamunur
Published: August 2024

About 14% of adolescents experience mental illnesses globally. The rate increased after the COVID-19 pandemic. This study aimed to estimate the prevalence of COVID-related major mental illnesses (depression and anxiety) and their predictors among adolescents. This community-based cross-sectional study was conducted among 350 adolescents aged 10-19 years, recruited from rural communities in West Bengal, India. The study areas included 27 subcenters in the Budge Budge II Block, which comprised 1,91,709 population and 45,333 households. Data were collected from randomly selected households by trained research assistants through house-to-house interviews. Pretested standardized questionnaires, Patient Health Questionnaire (PHQ) for depression, Generalized Anxiety Disorder (GAD) for anxiety, and a demographic questionnaire were used for data collection. The prevalence of anxiety was 35.7% (125 out of 350), and the prevalence of depression was 30.0% (105 out of 350). Females had significantly higher scores of anxiety (6.67 ± 4.76 vs. 3.42 ± 3.17, respectively, p <0.001) and depression (5.51 ± 4.99 vs. 3.26 ± 3.86, respectively, p <0.001) compared to males. Adolescents who had COVID-19 cases or deaths in the family had significaly higher scores of anxiety and depression compared to those who didn’t have these events. In multivariate analysis, the statistically significant predictors of anxiety were COVID-19 death in the family, COVID-19 cases in the family, female gender, and a lower income group (p <0.001 for all). For depression, the significant predictors included COVID-19 death in the family, COVID-19 cases in the family, female gender, a lower income group, and a higher age group in adolescents (p <0.001 for all). Based on the study results, we recommend that immediate attention is needed for adolescents’ mental health support and coping with stresses following COVID-19.