bluuebunny/crossref_metadata_2025 huggingface dataset:
Alejandro de la Sota y el sueño de habitar el Mediterráneo
Authors: Pascual Rubio Ana , Bravo Bravo Juan
Published: December 2024

Alejandro de la Sota es un maestro esencial de la arquitectura española del siglo XX. A lo largo de su obra, la atención a lo popular se revela como una constante que evoluciona desde la asimilación casi literal de sus primeras realizaciones, hasta la sintetización de sus elementos esenciales, a través de la abstracción y el empleo de nuevos materiales, de sus últimas propuestas. Desde esta perspectiva, el objetivo del presente artículo es analizar la influencia de la arquitectura popular en su producción, a través del estudio de la documentación original que se conserva de diversas propuestas domésticas, algunas de ellas inéditas, realizadas por el arquitecto para el entorno del Mediterráneo, entre los años cincuenta y ochenta. Ninguna de ellas llegará a materializarse, de manera que quedarán en el ideario del arquitecto como un anhelado sueño; el sueño de habitar el Mediterráneo.
Las otras fábricas de Curro Inza
Authors: Verdasco Novalvos Ángel
Published: December 2024

Curro Inza, arquitecto miembro del Organicismo madrileño, desarrolló una primera etapa de construcciones fabriles que terminó en 1966 con la construcción de la primera fase de la fábrica de embutidos de Segovia. Pero existe una segunda etapa de proyectos industriales aún desconocidos y por estudiar. Tras terminar Segovia, se traslada al año siguiente a trabajar y enseñar en Pamplona.Y desde allí dejará escritas una serie de reflexiones sobre cómo enfrentarse al proyecto fabril. Reflexiones que determinarán los proyectos de la segunda etapa fabril que incluye la ampliación de Segovia y varias fábricas construidas en Navarra. En ellas el arquitecto desarrolla asuntos como el interés por lo metálico, lo epidérmico y las estructuras ligeras de grandes luces que hastael momento no había utilizado. Estos proyectos sirven para conocer la obra completa del autor pues las fábricas navarras son, hasta día de hoy, un conjunto de proyectos desconocidos, en parte debido a que la repentina muerte del autor limitó su difusión y conocimiento.
La Bolsa de Berlage
Authors: Molema Jan , García García Rafael
Published: December 2024

La Bolsa de Ámsterdam proyectada por Berlage entre 1896 y 1903 con un proyecto de concurso previo entre 1884 y 1885, fue el edificio central y gran punto de inflexión en la obra del arquitecto neerlandés. El tema tratado en este artículo pone el foco en la decisión de basar el proyecto en un riguroso sistema modular, lo cual fue realizado en 1898 modificando de forma importante el estado previo del proyecto. Con dicha premisa, se indaga en las razones que motivaron dicho cambio, prestando especial atención a las influencias culturales y al contexto urbano en que se proyectó. La parte nuclear es, no obstante, el análisis del sistema modular sobre el que a través de un minucioso trabajo de observación se desvela su novedad e importancia, más allá de la conocida trama de triángulos reflejada en los bien conocidos dibujos de sus alzados. En forma casi cristalina, todo el edificio en su tridimensionalidad resultó ser un exacto entramado que tomó como punto de partida un laborioso trabajo de encaje de modulación de su planta. Sobre ella, el sistema de proporciones basado en el triángulo egipcio encontró múltiples resonancias no solo en los alzados sino también en sus espacios principales.
Hubungan antara Faktor Karakteristik Petani dengan Tingkat Adopsi Budidaya Padi Varietas Ciherang di Kabupaten Bangkalan
Authors: Putri Cut Adira Titania , Sugihardjo Sugihardjo , Lestari Eny
Published: December 2024

The Ciherang variety developed by the Department of Agriculture’s Research Center is useful for increasing rice productivity and obtaining varieties that are resistant to pests and diseases. Bangkalan Regency seeks to support agricultural development by introducing the Ciherang variety as a step to increase production and the welfare of farmers in the region. The ability to accept an idea is different for each individual, including farmers. Therefore, this study needs to be conducted to determine the factors of farmer characteristics in the level of adoption of Ciherang rice cultivation in Bangkalan Regency. This study aimed to determine the relationship between farmer characteristic factors and the level of adoption of Ciherang rice cultivation in Bangkalan Regency. This research uses quantitative methods, including field survey techniques and purposive sampling techniques, to determine the research location in Bangkalan Regency. The research sample was taken as many as 60 farmers using proportional random sampling technique. Data analysis in this study used the Spearman rank correlation test. The results showed that internal and external factors of farmer characteristics in the form of age, education level, farming experience, land tenure status, and information sources have a significant correlation to the level of adoption of Ciherang rice cultivation in Bangkalan Regency. In contrast, farm size and extension worker intensity do not have a significant correlation with the level of adoption of Ciherang rice cultivation in Bangkalan Regency.
Identifikasi Perencanaan, Implementasi dan Evaluasi Program Corporate Social Responsibility Perusahaan Karet di Kabupaten Tulang Bawang Barat, Lampung
Authors: Gitosaputro Sumaryo , Irawan Sahrul Ari
Published: December 2024

Corporate social responsibility (CSR) is one of the mandatory programs implemented by companies that contributes to the progress of the nation. Private companies, state-owned companies, and Regional-Owned Enterprises (BUMD), especially private companies, are not entirely optimal in implementing CSR. This study aims to determine the extent to which CSR planning, implementation, and evaluation at PT. Huma Indah Mekar are given to the community around the company's area. This study is a field study accompanied by an internship. The research is a qualitative descriptive type using interviews and observations as research instruments. The research was conducted at PT. Huma Indah Mekar by making human resource development (HRD) and HRD Staff as informants. The results of this study show that the CSR program in the company has been well planned, from building renovation, education scholarships, blood donation, and mass circumcision. The targets, objectives, and implementation forms have been prepared and planned well by the company's CSR team. The implementation of this CSR program includes the place, actors, objects, and feelings of the community around the recipients of the CSR program. The evaluation of the program that has been implemented provides an illustration of the need for improvement and re-planning of future CSR programs.
Isotermas de sorción de ingredientes y dietas para aves de corral
Authors: Sordi C. , Tavernari F.C. , Surek D. , Sartoretto L.M. , Teixeira C.J.S.
Published: December 2024

Este estudio tenía como objetivo determinar las isotermas de absorción de los ingredientes y la dieta de las aves. Las muestras se encapsularon en cápsulas y se deshidrataron por secado en horno en un desecador durante más de 24 horas. Las muestras se transfirieron al desecador que contiene agua en la base y se colocaron en el horno, retirándose una muestra de cada material a intervalos incrementales. La muestra se pesó y para la determinación de la actividad del agua y la materia seca. Los datos de humedad y actividad del agua fueron evaluados por ocho modelos matemáticos. El modelo matemático del GAB ajustó los datos experimentales para constituir la isoterma de cada material. Se encontraron isotermas de sorción de tipo II, excepto para el BHT: valores demostrados que no encajaban en la determinación de la isotermia. El comportamiento higroscópico de los ingredientes fue: L-treonina, piedra caliza, BHT, DL-metionina, L-valina, L-triptófano, fosfato, caolín, suplemento vitamínico, sal, desactivador de micotoxinas, dieta del gallo en pellets, dieta del gallo en pellets, dieta de la capa de puré, dieta de capas peletizadas, maíz, bacitracina-zinc, suplemento vitamínico mineral, fitasa, salvado de arroz, salvado de trigo, suplemento mineral, salvado de soja, coccidiostático, L-lisina HCl y cloruro de colina. Los ingredientes y las dietas tienen diferentes comportamientos higroscópicos: pueden llevar a un deterioro y a una baja precisión en los valores nutricionales de la dieta, ya que la formulación se basa en su estado.
Caracterización de parámetros de calidad seminal en variedades amenazadas de la raza porcina Ibérico
Authors: Díaz-Ruiz E. , González-Ariza A. , León J.M. , Peláez-Caro M. , Venegas M. , Forero F.J. , Salgado J.J. , Pérez-Marín C.C. , Navas-González F.J. , Delgado J.V. , Galán-Luque I. , Arando A.
Published: December 2024

El cerdo Ibérico es una raza autóctona española que se encuentra ampliamente distribuida en las zonas de dehesas del suroeste peninsular donde juega un papel fundamental en la conservación de dicho ecosistema. El objetivo del presente trabajo fue llevar a cabo una caracterización de distintos parámetros indicativos de la calidad seminal en tres variedades de cerdo Ibérico. Para ello, se utilizaron sementales de las variedades Retinto del Andévalo, Torbiscal y Negro de los Pedroches, analizándose 16 muestras por animal, y valorándose en cada eyaculado las variables volumen, concentración, morfología, motilidad y parámetros cinemáticos. Según los resultados obtenidos se observaron diferencias significativas para todas las variables estudiadas excepto para la velocidad curvilínea (VCL) e índice de rectitud (STR). En relación al volumen espermático, se observaron diferencias significativas entre sementales, siendo el verraco nº 2 de la variedad Retinto del Andévalo quien presentó el valor más alto (89.4 ± 15.39 mL). En cuanto a la concentración espermática, el ejemplar de la variedad Negro de los Pedroches fue quien reportó mayor concentración media (467.6 ± 71.84 x 106 spz/mL), siendo así mismo el que presentó un mayor porcentaje de morfoanomalías. Finalmente, los valores de motilidad total y progresiva fueron más elevados en el verraco nº 1 de la variedad Retinto del Andévalo (91.98 ± 2.86% y 61.67 ± 5.92%, respectivamente). En conclusión, la calidad seminal observada en los verracos de la raza porcina Ibérico en el presente estudio, es apta según los valores de referencia para la especie para su uso en programas de reproducción asistida, a excepción del ejemplar de la variedad Negro de los Pedroches el cual posee un alto número de morfoanomalías.
Situación actual y perspectivas del sector caprino mundial y español
Authors: Salgado J.J. , González-Ariza A. , Díaz-Ruíz E. , Peláez-Caro M.P. , Galán-Luque I. , Delgado J.V. , Navas-González F.J. , Camacho M.E.
Published: December 2024

El caprino ya no es una especie ganadera marginal, sino que está tomando cada vez más peso en la producción animal internacional. En países de renta media y baja, donde se concentra más del 95% del censo mundial, el caprino supone un pilar fundamental para la obtención de carne, leche y queso, y se explota en pequeños rebaños, siguiendo unas prácticas de manejo rudimentarias y bajo climas extremos. En países desarrollados, por otro lado, el sector se ha especializado en la producción lechera muy tecnificada, la carne se considera un subproducto y los censos están disminuyendo, pues la tendencia actual es a tener menos granjas, pero de mayor tamaño y eficiencia. España es una potencia productora de leche caprina, líder en tecnificación y genética, aunque aún conserva rebaños de razas muy rústicas que se explotan en sistemas tradicionales de pastoreo y que aportan diversos beneficios a nuestra sociedad. En esta revisión se exponen los censos y producciones caprinas mundiales y nacionales en la actualidad, así como su evolución y tendencia. Además, se analiza el impacto económico de la pandemia en el sector español, y se habla de las perspectivas y dificultades a las que se enfrenta.
Caracterización de las curvas de crecimiento biológico de la gallina Andaluza Azul, una raza local amenazada
Authors: Galán I. , Arando A. , González A. , Navas F.J. , Salgado J.I. , Díaz E. , Peláez M.P. , León J.M. , Delgado J.V. , Camacho M.E.
Published: December 2024

El objetivo del presente estudio fue realizar una evaluación de las curvas de crecimiento de la raza aviar Andaluza Azul, raza que se encuentra en estado amenazado y tiene su censo concentrado en Andalucía. Aunque actualmente se cría generalmente como una raza ornamental, su producción puede ser considerada al desarrollar sistemas alternativos de producción, y el huevo, que es su producto principal, tiene características diferenciadas al compararlo con los comerciales. Para el análisis de los datos de crecimiento se ajustaron modelos de Gompertz, Von Bertalanffy, Brody, Verhulst y logístico, basándose en cinco criterios de bondad de ajuste y flexibilidad: cuadrado medio del error, Pseudo-R2, criterio de información de Akaike, criterio de información de Akaike corregido y criterio de información bayesiano. Para las hembras, la función que mejor ajustó fue la de Gompertz, mientras que Von Bertalanffy fue el modelo de mejor ajuste para los machos. Los valores para los parámetros a (peso adulto), b (constante) y k (pendiente) o m (determinación del punto de inflexión) se obtuvieron al ajustar estos modelos según el sexo. Se obtuvieron valores de 1861,96 y 3000,81 g para el parámetro a, para gallinas y gallos, respectivamente. Los valores de b fueron 4,240 y 0,865 para hembras y machos, respectivamente, mientras que los valores de k fueron 0,021 (hembras) y 0,013 (machos), lo que indica que la raza Andaluza Azul tiene valores muy similares a otras razas mediterráneas que fueron inicialmente seleccionadas para la producción de huevos y que se han criado tradicionalmente en sistemas extensivos.
Caracterización etnológica de vacas criollas en el Estado de Campeche, México
Authors: López-Caraveo E. , Estrada-León R.J. , Severino Lendechy V. , Bojórquez-Cat J.C. , Moo-Huchin V,M, , Sierra-Vásquez A.C.
Published: December 2024

Las vacas criollas de Nunkiní (VCN) en Campeche, son una población reducida que aún subsisten en condiciones nutricionales y sanitarias difíciles y, en los últimos años se han visto afectadas por los cruzamientos con otras razas mejoradas, a pesar de sus características de adaptabilidad y rusticidad. El objetivo de la presente investigación fue realizar una caracterización etnológica de VCN bajo condiciones tropicales del Estado de Campeche, México. Se eligió una muestra de 46 vacas seleccionadas en diez unidades de producción pecuarias (UPP) pertenecientes a la comunidad de Nunkiní, Campeche. Se evaluaron siete características fanerópticas, seis morfológicas, se determinó la edad, y diez rasgos morfométricos, además de nueve índices zoométricos. Los datos fueron analizados mediante estadística descriptiva, coeficientes de correlación y análisis clúster, utilizando el paquete estadístico SAS®. Se encontraron nueve variantes del color del pelaje siendo las más frecuentes: el hosco (24%), negro (21.7%), rubio (15,2%) y blanco (13%), respectivamente. El peso corporal promedio fue de 256.76±47.09 kg y la edad de 8.5±4.28 años. Los coeficientes de correlación de Pearson mostraron que la mayoría de las variables están relacionadas significativamente (P
Perfil morfológico e faneróptico do remanescente do Cavalo	Nordestino no estado da Paraíba, Brasil
Authors: Ribeiro N.L. , Medeiros G.R. , Costa J.H.S. , Santos S.G.C.G. , Nascimento G.V.
Published: December 2024

Objetivou-se com o presente trabalho caracterizar o perfil fenotípico, através de caracteres morfológicos e fanerópticos do remanescente do Cavalo Nordestino no estado da Paraíbae auxiliar no processo de atualização do padrão racial junto a Associação Brasileira dos Criadores de Cavalo Nordestino (ABCCN). Foram utilizados 200 animais ao acaso, a partir de 3 anos de idade (25 machos inteiros, 69 machos castrados e 106 fêmeas). A avaliação foi feita visualmente e as informações, anotadas em caderno fichado. Foram avaliadas características qualitativas, como coloração da pelagem, perfil cefálico e de chanfro, forma do pescoço, inclinação da garupa, inserção de cauda, largura do peito, formato do olho, cor e tamanho dos cascos. Assim, cada caractere recebeu uma sequência de números, correspondente a cada classe fenotípica. Na distribuição da pelagem observa-se uma diversidade nos tipos de pelagens encontradas, destacando-se a tordilha (35,95%), castanha (34,24%), seguido da alazã (14,87%), foram encontradas pelagens baia, preta e tobiana. O perfil do chanfro com maior frequência é do tipo reto 73,58%; 56,00% e 79,71% fêmeas, machos inteiros e castrados, respectivamente, seguido do subconvexo. A conformação da garupa mostrou-se em sua maior frequência do tipo ligeiramente inclinada, e em menor frequência a horizontal. Os animais avaliados apresentam, em geral, pelagem predominantemente castanha e tordilha, chanfro retilíneo e subconvexo, pescoço piramidal, cascos pequenos, escuros ou pretos, garupa ligeiramente inclinada e cauda de inserção baixa.
Desenmarañando Hilos Temporales: Evaluando Correlaciones en las Líneas Temporales de Asociaciones de Razas Caninas Autóctonas en las Islas Baleares
Authors: Alanzor Puente J.M. , Pons Barro Á.L. , González Ariza A. , Marín Navas C. , Concepción Felipe I. , Delgado Bermejo J.V. , Navas González F.J.
Published: December 2024

Este estudio investiga las dinámicas temporales del reconocimiento de razas autóctonas de perros en las Islas Baleares, revelando una compleja interacción de relaciones a lo largo de diversas etapas. El análisis, representado a través de un mapa de calor y una matriz de correlación, destaca la importancia del reconocimiento temprano de las razas al mostrar fuertes correlaciones negativas con etapas posteriores, dando forma a la trayectoria para la preservación estandarizada de las razas. Las asociaciones emergen como actores centrales, exhibiendo correlaciones positivas en sus dinámicas temporales y contribuyendo significativamente a la sostenibilidad del ecosistema isleño. Notablemente, el estudio identifica conexiones matizadas entre la secuencia temporal del desarrollo de las asociaciones y los logros subsiguientes de reconocimientos oficiales autonómicos y nacionales. Los hallazgos proporcionan perspectivas valiosas sobre los patrones intrincados que rigen la preservación de las razas, ofreciendo una guía integral para estrategias de conservación informadas y contribuyendo a esfuerzos más amplios en la conservación de la biodiversidad y la tutela del patrimonio cultural único de las Islas Baleares.
Reanudación de la actividad ovárica posparto en ovinos en el trópico alto colombiano
Authors: Alvarado G.P. , Torres C.M. , Grajales L.H.
Published: December 2024

Se evaluó el comportamiento de la condición corporal, peso vivo y niveles de progesterona en el posparto durante el periodo de reanudación de la actividad ovárica, en función del tipo racial (Criolla Colombiana, Romney Marsh, Hampshire y Corriedale) y tipo de parto (sencillo y múltiple) en 32 hembras ovinas. La estadística se realizó bajo un modelo de estructura factorial, usando el paquete SAS. Dentro de los resultados se encontró que la condición corporal y el peso empiezan a recuperarse a partir del día 21, siendo la Criolla y la Romney Marsh las que inician más tempranamente; el tiempo de reactivación ovárica posparto fue de 31,8 ± 14,1 días en promedio, sin presentar diferencias significativas dentro de los grupos evaluados. El tipo de parto presentó un efecto significativo en el intervalo parto primera ovulación (P
Hierbas tropicales (Phyllantus amarus, Moringa oleifera y Viscum album) como aditivo alimentario en la producción de conejos: efectos sobre el rendimiento, hematología, bioquímica sérica y marcadores de estrés oxidativo
Authors: Jimoh O.A. , Daramola O.T. , Okin-aminu H.O.
Published: December 2024

Objetivou-se avaliar o comportamento ingestivo de vacas de leite submetidas a níveis de ureia na dieta a base de silagem de sorgo. Este estudo foi realizado após a aceitação pelo Comitê de Ética em uso animal da Universidade Estadual do Piauí, caso nº 0356/19. Foram utilizadas 05 vacas lactantes ¾ Holandês x ¼ Gir Leiteiro, no terço médio de lactação, com idade média de 60 meses e peso corporal médio de 518 kg ± 52 kg que foram distribuídas em cinco tratamentos, em delineamento experimental de quadrado latino 5x5. Os tratamentos U-50; U-75; U-100; U-125 e U-150 correspondiam a 51,2; 77,7; 104,1; 140,8 e 173,5 g de ureia consumidos por dia, respectivamente. As avaliações do comportamento foram realizadas no 20º dia de cada período, sendo feitas observações a cada cinco minutos, por um período de 24 horas, sendo feitas cinco avaliações, totalizando 120 horas de avaliações. A análise dos dados foi realizada pelo procedimento de análises de variância e regressão (SAEG versão 9.0). Adotou-se como nível de significância 0,05. Não houve efeito (P
Influência do equilibrio eletrolítico da dieta na absorção e metabolismo de aminoácidos em animais não ruminantes
Authors: Maia K.M. , Pozza P.C. , Dalcin L.C. , Vasconcellos R.S. , Marcato S.M.
Published: December 2024

As aves e os suínos são animais considerados homeotérmicos, porém estes animais apresentam a necessidade de serem criados em ambientes com temperatura a umidade controlados. Pois a exposição ao estresse térmico durante seu desenvolvimento pode resultar na diminuição do consumo causando distúrbios metabólicos, como a alcalose respiratória, que provoca quedas no desempenho e produção. Visando diminuir estes efeitos uma das medidas é a redução na quantidade de proteína bruta, assim como a correção dos íons envolvidos no balanço eletrolítico da dieta. O equilíbrio eletrolítico influência função na regulação ácido-base do organismo e no metabolismo dos aminoácidos. Portanto esta revisão tem como objetivo elucidar a influência que o balanço eletrolítico da dieta tem sobre a absorção e metabolismo dos aminoácidos em animais não ruminantes. A correção do cálculo no balanço eletrolítico e a redução nos níveis de proteína nas dietas podem evitar distúrbios metabólicos, além de promoverem melhoras no desenvolvimento. Porém, há necessidade de mais pesquisas relacionado o efeito que o balanço eletrolítico pode causar sobre a absorção dos aminoácidos, haja visto que os dados encontrados na literatura são bastante conflitantes.
Importancia de la acreditación de la educación superior en el Ecuador
Authors: Enríquez Estrella Miguel Ángel , Fernández-Sánchez Lineth , Sancho Aguilera David , Loaiza Maldonado Iliana del Cisne
Published: December 2024

Accreditation of higher education in Ecuador takes on a paramount significance for the development of academic activities. This study focuses on the distinction between evaluation and accreditation, emphasizing their relationship. The accreditation in Ecuadorian higher education is addressed, considering parameters such as teaching, research, and engagement with society, highlighting its relevance. The employed method centers on the construction and analysis of the Referential Framework, playing a crucial role in providing a clear and accessible understanding of the research topic. The results underscore the importance of continuous training and knowledge updates in university education, especially in an environment characterized by constant changes. In conclusion, the need for implementing continuous evaluation processes at all levels of the educational institution is emphasized.
Una aproximación documental a la gentrificación debida al turismo en los espacios rurales
Authors: Zarza Ballina Joana , Cruz Jiménez Graciela
Published: December 2024

Tourism as a solution to the problems of rural communities has generated various unwanted situations such as gentrification, which has diverse environmental implications. The aim of the article is to analyze the scientific production on tourism-related gentrification to identify knowledge gaps and formulate research proposals that contribute to the topic. For this purpose, documents from 2008 to 2022 were consulted, including open access sources on Google Scholar and restricted access from Elsevier. This resulted in categorization into four thematic lines: Socio-spatiality and Socio-spatial and Sociocultural Impacts of Tourism-related Gentrification, Capitalism and Displacement, Gentrification in Rural Areas, and Gentrification and Government. It is concluded that the third line is of increasing interest in publications on gentrification, given the challenges faced by rural tourist areas.
Evaluación de la calidad de cuatro playas de Tacna (Perú) utilizando índices basados en desechos marinos
Authors:   , Zorrilla Herrera Carla Isbel
Published: December 2024

Se analizaron cuatro playas (Los Palos, Tres Cruces, Caleta Vila Vila y Los Hornos) de la región de Tacna, Perú con el objetivo de determinar los índices de calidad de desechos marinos durante la temporada de verano. Se tomó un área de 100 m2 para cada una de las cuatro playas, en las que se recolectaron siete categorías de desechos marinos: plástico, metal, vidrio, papel, tela, caucho y desechos peligrosos, en intervalos de cada 15 días en seis visitas. El principal desecho encontrado fue el plástico (54.18%), seguido por el papel (26.10%), metal (10.25%), desechos peligrosos (3.55%), tela (2.84%), y el caucho (0.32%). Se determinaron seis índices basados en desecho marinos: densidad de desechos marinos en donde la playa con mayor densidad fue Los Palos; dos índices de diversidad, Shannon-Wiener y equitatividad de Pielou, encontrándose que las cuatro playas fueron bajas en diversidad y con dominancia en los residuos plásticos. Finalmente, tres índices de calidad, donde el Índice general mostró que la Playa Los Hornos está en la categoría "Limpio" y las otras playas en "Sucio". El Índice de costa limpia que presentó la playa Los Hornos en "Limpio" y las otras tres playas en "Moderado". Para el Índice de artículos peligrosos se evidencia que la playa Tres Cruces está en la "Clase III", la playa Los Hornos en la "Clase V" y las otras dos playas en la "Clase IV". Los índices de calidad basados en desecho marinos permiten clasificar las playas de Tacna, Perú.
Imbalance in the duality of criminal activity and its proving
Authors: Afanasyev A. Yu.
Published: December 2024

Objective: to verify and confirm (or refute) the hypothesis about the mismatch between the means of proof and the means of criminal activity in terms of strength and diversity, which causes imbalance in the dualism of criminal activity and its proving.

   Methods: in solving the research problem, we used, first of all, dualistic and hypothetical-deductive methods, as well as methods of functional systems, comparison and other general scientific methods.

   Results: criminal activity and its proving show the dualism of two complex functional systems, which are opposite, not reducible to each other, equal, but not equipollent. The lack of equipollency is manifested in the inconsistency of the means of proof with the means of criminal activity in terms of strength and diversity. On the one hand, the available means of proof are outdated and limited; on the other hand, they are used ineffectively when forming evidentiary systems of different levels. This leads to imbalance in the dualistic system. This is confirmed by systemic problems of reality – critically low disclosure rate, violation of the rights and freedoms of participants in criminal proceedings, low level of compensation for damages from crimes, protracted procedures of multi-volume criminal cases, etc.

   Scientific novelty: for the first time, the activity of proving is presented as a complex functional system, which together with criminal activity forms a dualism. In this dualistic system, an imbalance is found, consisting in the non-equipollent relationship between the two functional systems, where the means of proving are inferior to the means of criminal activity both in strength and in diversity. In this regard, the article attempts to reveal the mechanism of proving in order to determine how the two sides in the dualistic system can be balanced.

   Practical significance: the provisions laid down in the study can in the future act as a methodological basis for improving the means of proving and increasing the effectiveness of forming evidentiary systems of different levels.
Dual panic theory: new Insight into moral panics
Authors: Adams O. L. , Behl J.
Published: December 2024

Objective: to comprehensively analyze the moral panic concept, developed in the works by S. Cohen, and to elaborate, on its basis, a new concept – the dual panic theory.

   Methods: dialectical approach to cognition of social phenomena, allowing to analyze them in historical development and functioning in the context of the totality of objective and subjective factors, which predetermined the following research methods: formal-logical, sociological.

   Results: Moral panics have been broadly discussed in the public discourse since S. Cohen’s (1972) seminal text on the topic. Despite copious research, we believe that the theory is in need of expansion due to the increased complexity of societal interactions. Through the lens of an increasingly polarizing American culture, we believe the original concept of moralpanics is overly simplified and no longer encompasses the intricacies of American society. Using the story of the McCloskey family’s 2020 interactions with Black Lives Matter protestors and Goode and Ben-Yehuda’s (1994) definitional criteria, we propose a new, expanded theory of moral panics – Dual Panic Theory.

   Scientific novelty: based on the analysis of the existing approaches to the moral panic concept, the paper offers and elaborates a new concept – the dual panic theory. It suggests that an event can happen that causes a competing panic by two opposing sides of an issue. Different from a culture war, dual panics are genuine panics about an action rather than a reaction to oppositional outrage from a competing interest group. Goode and Ben-Yehuda argue that researching moral panic cannot be complete without an examination of all societal levels, from elites to grassroots, and the full spectrum from ideology and morality at one end to crass status and material interests at the other. As society has evolved, so too must the theoretical explanations of societal reactions, moral panic or otherwise.

   Practical significance: the main provisions and conclusions of the article can be used in scientific, pedagogical and law enforcement activities when considering the issues related to the moral panic concept.
Long-term clinical outcomes with an average of 6 years follow-up in dRTA patients treated with ADV7103 an oral twice-daily fixed and prolonged-release combination of potassium bicarbonate and potassium citrate (Sibnayal®).
Authors: Bertholet-Thomas Aurelia , de-mul Aurelie , Roussey-Kesler Gwenaëlle , Podracka Ludmila , Novo Robert , Nobili Francois , Knebelmann Bertrand , Harambat Jerome , Golubovic Emilija , Boyer Olivia , Maio Massimo Di , Caillez Mathilde , Baudouin Veronique , Chidler Laure , Leblanc Veronique , Bacchetta Justine
Published: December 2024

Background:
Distal renal tubular acidosis (dRTA) is a rare disease characterized by hyperchloremic metabolic acidosis affecting growth, bone and kidney health.
Methods:
The aim of B22CS study was to evaluate long-term safety and efficacy of ADV7103, a prolonged-release alkalizing formulation with twice daily dosing, in children and adults with dRTA.
Results:
A total of 30 patients with inherited dRTA (mean age:10.6±6.0 years) already treated with ADV7103 entered this long-term study (average of 6 years).
ADV7103 was well tolerated over the study duration. ADV7103 allowed a sustained control of metabolic acidosis as plasma bicarbonate level was 22.0±3.2 mmol/L at baseline versus 22.6±2.5 mmol/L at the End of Follow-up (EoF), p=NS.
From baseline to EoF, mean Z-score height significantly increased (-0.6±1.0 to -0.3±1.0, p=0.03), without significant change in weight and body mass index. Kidney function remained stable from baseline to EoF: estimated glomerular filtration rate =105±17 and 104±20 mL/min/1.73m2, respectively, p=NS.
Urinary ratios: Calcium/Creatinine (UCa/UCr), Citrate/Creatinine (UCi/UCr), Calcium/Citrate (UCa/UCi) were not significantly different between baseline and EoF (p=NS). Both percentages of patients with nephrocalcinosis and with nephrolithiasis remained stable between baseline and EoF (p=NS).
Mean lumbar bone mineral density Z-score significantly increased from baseline (-1.1±1.0) to EoF (-0.8±1.0), p=0.005, with significant improvement between baseline and EoF in pre- and post-pubertal patients (p=0.035 and p<0.001, respectively), whilst it was maintained in pubertal patients (p=NS).
Conclusion.
Long-term data support the good safety and efficacy profile of ADV7103 in the treatment of dRTA with adequate control of metabolic acidosis, stable kidney function and significant positive long-term clinical outcomes.
Influence of a preload on the fatigue behaviour of S355 and S700 cruciform joints
Authors: Guilmois Lauriane , Huther Isabel , Jubin Laurent , Lefebvre Fabien , Leray Vincent
Published: December 2024

Preload application techniques are often used to verify the structural integrity of mechanical systems. Generally, these procedures are performed after the fabrication but before the commissioning of such equipment, without any assessment of the preload impact on fatigue behaviour. These approaches are imposed by standards such as ASTM or DNV that define applicable preload conditions but neither technical justification nor quantification of the impacts are usually given. The aim of this study is to evaluate the effect of a preload for various levels of plastic strains on structural steel S355 or high-strength steel S700 cruciform joints. Fatigue tests were performed in tension (R = 0.1) without preload as reference and after two different levels of preload corresponding to, on one hand a local stress close to the weld toe equal to 1.25 times the yield stress and on the other hand a local stress equal to 1.56 times the yield stress. The fatigue results show an increase of the fatigue strength, depending on the configuration (load-bearing weld beads or load-bearing weld beads), between two and seven FAT classes for the highest level of preload.
Comprehensive Analysis of PIK3CA Mutations in Advanced Colorectal Cancer Using Circulating Tumor DNA Profiling
Authors: Milsap Allante , Tsai Jill , Jafry Baqir , Kim Alex , Kazmi Syed , Verma Nilesh
Published: December 2024

Mutations in PIK3CA are prevalent in advanced colorectal cancer (CRC) and are associated with advanced-stage disease and poor prognosis. However, the prognostic value of these mutations remains unclear. In order to better understand their role in CRC progression, we evaluated the genomic landscape of PIK3CA mutations (PIK3CAm) in advanced CRC using plasma-based ctDNA from ~17,000 samples (Guardant360 database). Mutation co-occurrence, MSI-H status, TMB scores, and exon-specific mutation frequencies were analyzed. Our study shows that the frequency of PIK3CAm (19.2%) and distribution of exons 9 and 20 are similar to those found previously in the literature. Our results demonstrate PIK3CAm having a low frequency of MSI-H co-occurrence, higher TMB scores, and increased co-occurring alterations with notable increased in APC, BRAF, EGFR, ERBB2and KRAS, which may suggest higher genomic instability. Our findings underscore the clinical significance of PIK3CAm in CRC and supports the development of tailored therapeutic strategies targeting this mutation.
Acceleration of the the MVS Workflow using Graphics Processors
Authors: Díaz-Cano Roberto , Folch Francesc , Quintana-Ortí Enrique S. , Alonso-Jordá Pedro
Published: December 2024

Computer Vision (CV) leverages artificial intelligence to analyse digital images, offering insights for a wide range of different applications. While CV software often relies on open source libraries such as OpenCV, it is probably more common for this software to use custom codes. Creating particular solutions stems from the very nature of the specific CV problems being addressed but, despite these particularities, there are common links at the core that are either not addressed by generic CV libraries or require significant customisation for specific applications. Understanding the nature of real problems faced by a digital image analysis use case can contribute as much as solving a generic CV problem, and this is the aim of this paper.
This article addresses the problem of migrating to CUDA a part of MVS, a complex CV workflow utilised in a real-world, industrial use case. The primary challenge lies in minimising the overhead due to data transfers between the host and GPU (graphics processing unit), or even within the device’s memory itself. While the speed-up achieved may not rival that of other applications more suitable to GPU architecture (in particular, massively data parallel applications), the algorithms and data distribution proposed in this study effectively offload a substantial portion of the workflow to the GPU in the context of low (integer) arithmetic intensity and real-time constraints. This frees the CPU to handle other workflow components and increases the capability to incorporate more cameras, significantly boosting productivity and economic performance.
Rational inattention as a transdiagnostic marker of mental disorders
Authors: Houser Troy
Published: December 2024

People tend to choose immediate payouts over larger payouts to be made in the future. This is called temporal discounting. Substantial research has indicated that steeper temporal discounting is associated with reduced self-control and various mental disorders, making it a plausible transdiagnostic marker of mental disorders. Recently, a novel theoretical framework and accompanying computational model has called into question the interpretation of temporal discounting as lack of self-control. Instead, this new framework suggests that temporal discounting is a function of uncertainty in cognitive representations of the future. This is an important distinction with regard to temporal discounting’s transdiagnostic standing because it means that reduced allocation of cognitive resources to representing future reward (rational inattention) is the transdiagnostic marker of mental disorders and not solely a lack of self-control. To test this possibility, here we compare the model of rational inattention to the classical hyperbolic model of intertemporal choice. We additionally evaluate the ability of rational inattention to predict a suite of psychopathological symptoms. We find that rational inattention does capture intertemporal choice better than the traditional model and that it correlates with dimensions of psychopathology. This work can inform cognitive-behavioral interventions of various mental disorders, as well as guide future research on intertemporal decision-making.
Psychological Responses to Acute Exercise in Patients With Stress-induced Exhaustion Disorder: a Cross-over Randomized Trial
Authors: Kling Jenny , Asplund Robert Persson , Ekblom Örjan , Blom Victoria
Published: December 2024

Background
Understanding acute psychological responses to physical exercise is important since they likely influence the initiation and maintenance of this behavior. Given its effectiveness in reducing symptoms in various psychological disorders, physical exercise should be further explored in Exhaustion Disorder (ED; ICD-10-SE: F43.8A), a condition characterized by persistent exhaustion following long-term psychosocial stress. Currently, no studies are available on the psychological effects of acute exercise in ED patients.
Aims
This study aims to (1) investigate the psychological responses to acute exercise in ED patients compared to healthy controls and (2) determine if these responses differ between low and moderate exercise intensities.
Methods
We conducted a two-armed cross-over trial in two groups: ED patients (n = 30) and healthy controls (n = 30). On two separate occasions, participants completed a 22-minute exercise at low or moderate intensity on a cycle ergometer, in randomized order. The main outcome was perceived fatigue, and secondary outcomes were feelings of energy, anxiety, stress, perceived exertion, and perceived psychological discomfort, all measured before, during, and up to 24 hours after exercise. Effects of the exercise conditions were assessed with repeated measures analysis of variance.
Results
ED patients reported higher exertion and psychological discomfort before and during exercise, higher fatigue, anxiety, and stress but lower energy throughout the trial compared to the controls. ED patients experienced more reduced fatigue and stress after both intensities (p < 0.05), and a more elevated energy after moderate-intensity exercise compared to controls (p < 0.05). No interactions between groups were found for anxiety over time. No differences were observed between pre-exercise and 6 hours or 24 hours post-exercise in any variables. The only intensity effect (p < 0.05) in the ED patients was a more pronounced energy decline 30 minutes after moderate-intensity exercise.
Conclusions
A 22-minute exercise was perceived as more strenuous by patients with exhaustion disorder and generated greater improvements in feelings of fatigue, energy, and stress compared to healthy individuals, without delayed negative changes. These findings can inform intervention design and guide clinical practice.
Trial registration
The study was retrospectively registered on 05/30/2024 at Clinical Trials.gov, with trial registration number 2022-04943-01.
Effect of antihypertensive drugs on mortality and readmission in new-onset hypertension patients with acute exacerbations of chronic obstructive pulmonary disease in hospitals: A multicenter retrospective observational cohort study
Authors: Wang Yi , Chen Jia-Hao , Lin Jian-Cheng , Sun Jia-Yan , Di Yin , Guo Qiang
Published: December 2024

Background: COPD is the third leading cause of death worldwide, and is often complicated by exacerbations, infections, and cardiovascular complications, which frequently result in poor patient prognosis.
METHODS: Patients were categorized into a good prognosis group and a poor prognosis group on the basis of their 28-day survival events and readmission status. Propensity score matching (PSM) was used to eliminate the interference of confounding factors between groups on clinical outcomes. Univariate and multivariate regression analyses were performed on both matched and unmatched cohorts to assess the impact of various factors on mortality.
RESULTS: Multivariate analysis of the unmatched cohort revealed that the use of DCCBs (HR = 2.006, 95% CI 1.202-3.350, P = 0.008) and elevated C-reactive protein levels (HR = 1.004, 95% CI 1.001-1.008, P = 0.013) were independent risk factors for hospital readmission within one year. Conversely, β-blocker use (HR = 0.230, 95% CI 0.068-0.772, P = 0.017) was a protective factor. In the PSM cohort, univariate analysis revealed that DCCB use (HR = 1.760, 95% CI 1.042-2.972, P = 0.034), FEV1% pred ≤ 40.10% (HR = 2.347, 95% CI 1.278-4.310, P = 0.006), and CRP ≥ 11.59 mg/L (HR = 2.084, 95% CI 1.242-3.497, P = 0.005) were independent risk factors for readmission within one year, wheras β-blocker use (HR = 0.227, 95% CI 0.067-0.765, P = 0.017) was a protective factor. Patients not treated with DCCBs had better prognoses than did those treated with DCCBs. Beta-blocker users had a lower readmission rate, although beta-blockers did not significantly affect the 28-day survival rate.
CONCLUSIONS: The use of DCCBs, FEV1% pred ≤ 40.10%, and elevated CRP levels were independent risk factors for readmission within one year for moderate to severe AECOPD patients with new-onset hypertension. Conversely, β-blockers were protective against readmission in this patient group.
Risk of recurrence in surgically treated Middle-ear Cholesteatomas - A retrospective cohort study
Authors: Jacobsen Line Voss , Rasmussen Simon Mylius , Schousboe Lars Peter
Published: December 2024

Cholesteatomas are benign tumors in the temporal bone which can damage surrounding structures through inflammatory, osteolytic activity. Surgery is the only curative treatment, but there is potential for recurrence. This study aimed to investigate the risk of recurrence after surgically treated middle-ear cholesteatoma in order to evaluate the need for post-operative follow-up. Medical records of patients with the diagnosis middle-ear cholesteatoma were thoroughly and systematically reviewed to gather information about surgery until recurrence, death or end of follow-up. Data was analysed by performing a time-to-event analysis and descriptive statistics. We found that among 267 included patients, 20% had recurrent disease. Stratified by age, 18% of the adults and 36% of the children experienced recurrence, with 78% of adults and 39% of children experiencing recurrence beyond the recommended follow-up time of 2 and 5 years, respectively. Children had a significantly higher risk of recurrence compared to adults. The majority of patients with recurrence were treated with mastoidectomy. In conclusion, the recurrence rate after cholesteatoma surgery is 20%, in accordance with previous findings. A prolonged, age-stratified and more systematic follow-up is suggested considering the high risk of recurrence in children compared to adults.
Assessing the Quality of Mortality Data in Zunyi, China: A Comparative Study of Garbage Coding Before and After Intervention
Authors: Zhang Bo , tang haibo , Wei Deqin , Long Tao , Huang Yuanmou , wang Jian , Zhang Yi , Shi Xiuquan , Tian Dalin , Guo Hailei , Cao Jiayan
Published: December 2024

BACKGROUND: Accurate mortality data are crucial for understanding mortality patterns, informing public health strategies, and evaluating national health programs. In 2022 and 2023, the Centers for Disease Control and Prevention in Zunyi, China, provided specialized training to staff responsible for cause-of-death surveillance.
METHODS: This study evaluated the quality of cause-of-death data reported by healthcare organizations in Zunyi city before and after the intervention, with a focus on the classification and extent of garbage codes. By comparing the distributions of various causes of death and their changes over the two years, we analyzed the differences and distribution patterns of garbage codes. The study participants were grouped by age and sex.
RESULTS: The cause-of-death data from Zunyi demonstrated good completeness over the two-year period. The proportion of definite causes of death increased significantly from 87.5% to 94.8%, whereas the proportion of unusable causes decreased notably, from 7.32% to 2.87%. Similarly, the proportion of garbage codes relative to total deaths decreased from 12.60% to 5.20%, with significant reductions in categories 3 and 5. The major garbage codes in both years exhibited a positively skewed distribution, which was primarily associated with aging and cardiovascular diseases. The proportion of garbage codes decreased across both the male and the female groups over the age of 65.
CONCLUSION: This study offers a cost-effective approach to improve the quality of cause-of-death data through a junk code-based assessment method. By implementing these measures, the accuracy and utility of cause-of-death data can be greatly enhanced.