bluuebunny/crossref_metadata_2025 huggingface dataset:
ENDOCRINOLOGIA PEDIÁTRICA: ATUALIZAÇÕES EM DISTÚRBIOS HORMONAIS NA INFÂNCIA
Authors: Coelho Giovanna Nunes Vrech , Simionato João Vitor Godinho , Carvalho Pedro Henrique dos Santos , Bontempo Reginaldo Lucas , Moura Renato Amorim Pereira De Carvalho , Pinto Diogo José Fonseca Monteiro , Mota Larissa Manhaes Chagas , Martins Bruna Menezes , Leal Maria Paula Barcelos Hundertmark , Polita Beatriz Rodrigues , Mano Eduarda Guedes Pereira de Azevedo , Carneiro Amanda Martins , Costa Karina Araújo Martins da , Moreira Henrique Correia , Freitas Edenizar Gomes de , Engleitner Júlia Nascimento , Fernandes Thayane Dias , Miguez Juliana Pinho , Junior Vanilson Pires Cerqueira , Neta Teresa Teixeira Ferreira , Nascimento Júlio César Machado do , Filho Rogério Lopes de Moura Fé , Pereira Narjara Samya Rodrigues , Giácomo Brenda Santana Araujo , Vieira Izadora Carneiro , Reis Davi Bayma
Published: April 2024

A endocrinologia pediátrica é uma área vital da medicina que requer constante atualização e pesquisa. Por meio do estudo dos distúrbios hormonais na infância e da endocrinologia pediátrica, é possível esperar a melhoria da qualidade de vida e o cuidado das crianças afetadas por esses distúrbios. Trata-se de um estudo cujo objetivo foi estudar atualizações mais recentes em distúrbios hormonais na infância, com foco na endocrinologia pediátrica. Nesse sentido, realizou-se uma revisão sistemática de literatura, com a seleção de estudos científicos publicados entre os anos de 2019 e 2024, disponíveis nas bases de dados Scielo, Medline e Lilacs. Após análise dos resultados, a principal conclusão é que avanços recentes na pesquisa genética têm proporcionado uma compreensão mais profunda das bases moleculares de distúrbios hormonais pediátricos, como a síndrome de Kallmann e a Síndrome de Prader-Willi, abrindo caminho para terapias mais direcionadas e eficazes no futuro.
Test of Acceptance of Batawoli-Based Nugget Modificationslocal Food Materials Milk Fish (Chanos Chanos) as Alternative Snack For Stunting Toddlers
Authors: Koestya Mutiara Devyntha Putri , Taufiqurrahman  , Hatijah Nur , Soesanti Inne
Published: April 2024

Stunting, a growth disorder in children characterized by height or length below the standard for their age, can be prevented by ensuring adequate intake of energy and protein. This study aims to assess the acceptability of modified Batawoli nuggets as a potential snack alternative for toddlers with stunting. The research employed a true experimental design with control and treatment groups. Organoleptic tests were conducted on Batawoli nugget formulations with varying ratios: F0 (1:0:1:1), F1 (1:2:1:1), F2 (1:1:1:1), and F3 (2:1:1:1). Data analysis utilized the Mann Whitney test. The findings reveal organoleptic test scores for each formulation: F0 scored 3.35 (somewhat liked), F1 scored 3.9 (somewhat liked), F2 scored 3.46 (somewhat liked), and F3 scored 3.52 (somewhat liked). The study concludes that the most preferred formulation, based on all indicators, is F1 (1:2:1:1), which provides an energy value of 3.5 kcal/g (>1.5 kcal/g) and a Protein Efficiency Ratio of 12.6% (within the range of 10% - 16%). Consequently, this formulation presents a promising local complementary food option for toddlers with stunting.
Organoleptic Test and Iron Level Test Tofu Moringa meatballs as an alternative snack for Teenage Girls
Authors: Akmalia Zida Shabrina , Christyaningsih Juliana , Hatijah Nur , Buanasita Annas
Published: April 2024

Many teenage girls in Indonesia suffer from anemia, prompting exploration into alternative dietary interventions. Moringa leaves, known for their high iron content, offer a potential solution. This study aimed to formulate tofu meatballs enriched with moringa flour, evaluating their iron content and organoleptic qualities as a feasible iron supplement for adolescent girls. Three tofu meatball formulations were tested: F1B with no added moringa flour, F2B with 5 g, and F3B with 10 g. Iron content was assessed using ICP-OES, and organoleptic tests were conducted. Statistical analysis included the Kruskal-Walli’s test, with Mann-Whitney test for significant differences. Results revealed F2B had the highest iron content at 1.34 mg/100 g, followed by F1B at 1.06 mg/100 g, and F3B at 1.23 mg/100 g. However, iron levels per serving fell short of the 10% daily requirement. While F1B was preferred for taste, aroma, color, and texture, F2B and F3B were still acceptable. Future improvements could involve using boiled moringa leaves and seasoning to enhance organoleptic qualities.
Description of Knowledge, Attitudes, Behavior of Snacking Habits and Nutritional Status of Students at MI Darun Najah Kloposepuluh Sukodono Sidoarjo
Authors: Millatal Haq Marisa , Intiyati Ani , Buanasita Annas , Nugroho Riezky Faisal
Published: April 2024

Street food is food that is sold and served by street vendors on the side of the road and in public places, which can be eaten directly without further processing or preparation. This study aims to describe the level of knowledge, attitudes, behavior, eating habits, and nutritional status of students at MI Darun Najah Klopoten Sukodono Sidoarjo. This research method uses a descriptive method. The total population of this study was 311 students in grades 4, 5, and 6 and a sample of 56 students was taken using Proportionate Stratified Random Sampling. Data collection was carried out through interviews with knowledge questionnaires, attitudes, FFQ forms, and anthropometric measurements. From the results of the study, most of the students had a sufficient category of knowledge (64.3%), good attitude (71.4%), frequent snacking behavior (53.6%), and good nutritional status (55.4%). From this, it can be concluded that most students still have sufficient knowledge and behavior of frequent snacking habits. It is recommended that the school hold outreach to students regarding information on snacks and nutrition and how to eat good and healthy snacks. School canteens are also expected to provide nutritious snacks.
EXERGAMES COMO RECURSO PARA A MELHORA DA MOBILIDADE, EQUILÍBRIO E APTIDÃO FÍSICA NA DOENÇA DE PARKINSON: UMA REVISÃO SISTEMÁTICA
Authors: Câmara Jorge Stéfani Caroline , Freitas da Costa Brunna Gabrielli , Lago Ferreira Cássio Bruno , Monteiro Jacob Mellina
Published: April 2024

Introdução: A Doença de Parkinson (DP) compromete a marcha, postura, equilíbrio e aptidão física. Muitos estudos utilizam a realidade virtual não imersiva (RVNI) como opção de tratamento para essas alterações. Objetivo: Analisar evidências científicas sobre os efeitos do uso de exergames sobre a mobilidade, equilíbrio e aptidão física de pacientes com DP. Métodos: Revisão sistemática nas bases de dados Cinahl, Embase, Medline, Lilacs, Pubmed, PEDro e Scopus, entre maio e agosto de 2021, com os descritores: “Parkinson”, “Virtual reality”, “Physiotherapy”, “Mobility”, “Balance” e "Exergames". Os critérios de elegibilidade foram: ensaios clínicos a partir de 2010 até junho de 2021 nos idiomas português, inglês e espanhol que utilizaram exergames comparados à fisioterapia convencional para o tratamento de pacientes com DP, tendo como desfechos: equilíbrio, mobilidade e aptidão física. Resultados: Oito artigos foram selecionados para a revisão. Foram extraídas informações relacionadas aos efeitos do uso de exergames sobre os desfechos citados, dados epidemiológicos, testes e escalas aplicadas. Conclusão: O uso de exergames contribuiu para a melhora significativa do equilíbrio, mobilidade e para os componentes “força muscular de membros inferiores” e “resistência cardiorrespiratória” da aptidão física. Porém, mais estudos sobre o uso de exergames  em outros componentes de aptidão física na DP devem ser feitos. Assim, o uso de exergames pode ser considerado como alternativa terapêutica para a melhora de tais desfechos em pessoas com DP.
Accounting Transformation in Digital Era
Authors: - Manisha Verma , - Rajanikant Verma , - Utkarsh Tripathi
Published: April 2024

The progression of technology has undeniably yielded a profound and incontrovertible influence upon the realm of accounting. Historically, accountants relied upon manual calculations and paper-based ledgers to reconcile financial statements, a practice that often resulted in the generation of imprecise and labour-intensive financial records, plagued by numerous computational inaccuracies. However, within the context of the present dynamic era, enterprises specializing in technology have pioneered the conception and refinement of automated accounting software, thereby facilitating a streamlined, precise, and time-efficient accounting process. Over recent years, the landscape of the accounting profession has experienced radical metamorphosis following the advent of blockchain technology and artificial intelligence, which have indelibly revolutionized the very foundations of accounting, ushering in new paradigms and prospective trends.
Building Flexible, Data-driven Framework for Real-time Analysis
Authors: - Srikanth Iyengar , - Yash Shingade , - Ayush Singh , - Kailas Devadkar , - Jignesh Sisodia
Published: April 2024

In the contemporary business landscape, the escalating demand for real-time predictive analytics is driven by the imperative for dynamic decision-making. Traditional analytics models often prove inadequate in addressing the need for agility required to respond swiftly to rapidly changing circumstances. Real-time predictive analytics, however, offers a transformative solution, empowering organizations to make informed and timely decisions in fast-paced environments. This capability proves invaluable in industries were staying ahead of emerging trends is critical, fostering a proactive approach to decision-making that can significantly impact competitiveness.

The sheer volume and diversity of data require sophisticated solutions for processing and analysis. Real-time predictive analytics becomes an indispensable tool, offering the capability to promptly extract valuable insights from massive datasets. This not only enhances decision-making but also allows organizations to stay ahead by uncovering trends and patterns in real time.

Scalability is a fundamental consideration for organizations on a growth trajectory. Real-time predictive analytics frameworks provide a scalable foundation, allowing businesses to seamlessly expand their analytical capabilities. This adaptability ensures that the framework can handle the increasing demands for processing power and storage, aligning with the evolving needs of a growing organization.
Assessing Passenger Satisfaction with Smart Airport Technologies: An Empirical Study
Authors: - Khushi Sharma
Published: April 2024

Airports serve as crucial components within the air transport value chain, necessitating continual adaptation to meet evolving technological demands and enhance passenger experiences. The evolution towards Smart Airports or Airport 3.0 underscores the imperative for modernization to facilitate safe, efficient, and seamless travel experiences, particularly pertinent amidst the challenges posed by events like the COVID-19 pandemic. This study delves into the concept of Smart Airports, focusing on passenger perceptions of technology and its role in shaping competitiveness within the tourism sector. Through an analysis of passenger perceptions and expectations, this research aims to provide a clearer understanding of the Smart Airport concept, considering gender perspectives, which represent a novel contribution to existing literature. Recognizing the pivotal role of air transport infrastructures in destination competitiveness, this study investigates the impact of technology improvements on passenger satisfaction and overall travel experience. By examining the relationship between airport technologies and passenger perceptions, satisfaction, and enjoyment, this research underscores the importance of integrating new technologies to enhance airport services and meet evolving passenger needs. The study further explores the potential of ICT in reducing travel time and enhancing overall passenger experiences, with a particular emphasis on understanding gender-specific influences on perceptions of airport technologies. Through a comprehensive analysis, this paper seeks to contribute to the ongoing discourse on Smart Airports and their significance in shaping the future of air travel.
A Comparative Study of Physical Fitness Components among National Level Hockey and Football Players of Rajasthan
Authors: - Megha Gehlot , - Dr. Santosh Lamba
Published: April 2024

For Hockey and Football players Speed, Strength and Endurance are the important variables according to the Sports Science. Keeping in view the concept, this study was taken to compare the level of Physical Fitness between Hockey and Football players. Total number of 40 National level (20 each) Football and Hockey player of Rajasthan. The age of subjects ranged between 18 to 28 years.

Data of Physical Fitness Components between Football and Hockey players was compared by using T Test. The level of significance was kept at 0.05 level of significant. The result of the study revealed that there was No significant difference between the Speed, Strength and Endurance of Rajasthan national level Hockey and Football players.
Battery Cell Thermal Control in Electric Vehicles Using Water Cooling Block
Authors: D. Sriram Sanjeev  , Dr. S. Gnanasekaran
Published: April 2024

Research and development efforts in the field of transportation have recently focused on creating clean, safe, and high-efficiency modes of transportation. It has repeatedly been predicted that electric, hybrid, and fuel-cell vehicles will soon displace conventional automobiles. This research offers an illustration of how a battery-electric vehicle may regulate the flow of coolant over specific battery cells. Each lithium-ion battery cell's heat level is measured by a sensor, which also controls the cooling process. The PID controller (Arduino) and Water Pump both function using a 12V rechargeable battery. Temperature sensors are employed to monitor each Li-ion battery cell independently and provide feedback as an analog signal. The flow of the pump is controlled by the battery's feedback, and the coolant goes via a convey to achieve temperature control. When compared to lead-acid / nickel-metal hydride batteries, lithium-ion batteries offer better energy densities. Moreover, it is far less expensive and doesn't need nickel or cobalt. Also, it is safer since it is more stable. Each battery cell has a water cooling block installed specifically for more effective cooling. When compared to the method of calculating the total battery heat without any controller on any individual cells of the battery, the method of implementing a water cooling block in individual cells will be more effective. The temperature variation in the battery cell was significantly decreased by a water cooling block, which also lowered the thermal effect by around 40%. In the battery cell, a number of cycles and the depth of discharge are recorded, and the findings show that while the coolant temperature rises from roughly 30°C to 50°C, the battery cell's interior temperature drops drastically from 60°C to 20°C of heat.
Keywords: Lithium-ion Battery, Temperature Monitoring, Temperature Management, Predictive Algorithms, and Sustainability
Effect of Heat Treatment on Magnetic Properties of EN8D Steel Used in Automotive Applications
Authors: Dr. S. C. Bali  , Vaibhav Bhavsar
Published: April 2024

The present study focuses on achieving the optimum combination of mechanical and magnetic properties for EN8D steel. SAE 1010 and EN8D steels are the candidate materials to manufacture the fixed nucleus of the disk-type electro-mechanical horn. Both materials have either good magnetic or mechanical properties. The main function of fixed nucleus is to get magnetized and pull the mobile nucleus towards it. However, as magnetization and demagnetization take place in the range of 300-500 Hz, fixed and mobile nucleus continuously strikes each other at high frequency. Due to such high frequency working condition, fixed nucleus is prone to failure under wear and tear or under fatigue. For this kind of application, a combination of magnetic and mechanical properties is required in the material used to manufacture fixed nucleus. Thus, in current paper, the effects of chemical composition, microstructure, hardness, strength and toughness of EN8D steel before and after austenizing and tempering heat treatment are evaluated and compared with as-rolled EN8D and SAE 1010 steels, which are mostly used for manufacturing fixed nucleus. Magnetic permeability was evaluated using JMatPro software and compared. Austenizing treatment is performed at 900 °C for 1 hour, followed by water quenching. Tempering treatment of the same was performed at 550 °C for 2.5 hours. The Ultimate Tensile Strength (UTS) and hardness of EN8D after heat treatment decreased from 917 to 781 MPa and 269 to 233 HV0.1 respectively. Charpy V-Notch (CVN) toughness of EN8D steel after heat treatment increased from 12 to 45 joules. It indicates that the decrease in strength and hardness resulted into increase in toughness. Microstructure changes from ferrite and pearlite to combination of tempered martensite, ferrite and bainite. Magnetic permeability evaluated by JMatPro software shows increment from 450 to 564 Gauss/Oersted in EN8D steel after heat treatment.
Keywords: Electro-mechanical horn, fixed nucleus, magnetic permeability, JMatPro, SAE1010 steel, EN8D steel
Lėtinio skausmo problema Lietuvoje ir pasaulyje
Authors: Rapalavičius Aurimas , Andriukaitytė Monika , Masionytė Justina
Published: April 2024

Lėtinis skausmas laikomas savarankiška liga, neigiamai veikiančia žmogaus fizinę, socialinę ir emocinę sveikatą. Lėtinio skausmo gydymas yra daugiadalykis, įtraukiantis įvairių specialybių gydytojus ir įvairius gydymo metodus, todėl sudėtinga užtikrinti, kad visi pacientai galėtų gauti tinkamą, prieinamą, įvairų, koordinuotą ir veiksmingą gydymą. Šiame straipsnyje aptariama lėtinio skausmo problema Lietuvoje ir pasaulyje. Tikslas. Analizuojant mokslinę literatūrą, išnagrinėti bei aprašyti lėtinio skausmo problemą Lietuvoje ir pasaulyje. Metodai. Literatūros paieška atliekama „UpToDate“, „PubMed“, „ScienceDirect“ ir „Cochrane Library“ duomenų bazėse. Dauguma apžvelgtų publikacijų yra ne senesnės nei 10 metų. Straipsnyje pateikiama tik apibendrinta mokslinės literatūros apžvalga. Išvada. Lėtinis skausmas išlieka plačiai paplitusia ir svarbia sveikatos priežiūros problema visame pasaulyje. Labai svarbu gerinti teikiamų specializuotų skausmo diagnozavimo ir gydymo paslaugų kokybę bei prieinamumą. Taip pat privalu užtikrinti, kad tiek nemedikamentinis, tiek medikamentinis gydymas būtų individualizuotas ir saugus.
Production benefits on encoding are modulated by language experience: Less experience may help
Authors: Brown Rachel M. , Roembke Tanja C.
Published: April 2024

Several lines of research have shown that performing movements while learning new information aids later retention of that information, compared to learning by perception alone. For instance, articulated words are more accurately remembered than words that are silently read (the production effect). A candidate mechanism for this movement-enhanced encoding, sensorimotor prediction, assumes that acquired sensorimotor associations enable movements to prime associated percepts and hence improve encoding. Yet it is still unknown how the extent of prior sensorimotor experience influences the benefits of movement on encoding. The current study addressed this question by examining whether the production effect is modified by prior language experience. Does the production effect reduce or persist in a second language (L2) compared to a first language (L1)? Two groups of unbalanced bilinguals, German (L1) – English (L2) bilinguals (Experiment 1) and English (L1) – German (L2) bilinguals (Experiment 2), learned lists of German and English words by reading the words silently or reading the words aloud, and they subsequently performed recognition tests. Both groups showed a pronounced production effect (higher recognition accuracy for spoken compared to silently read words) in the first and second languages. Surprisingly, the production effect was greater in the second languages compared to the first languages, across both bilingual groups. We discuss interpretations based on increased phonological encoding, increased effort or attention, or both, when reading aloud in a second language.
It is So Lonely Without You’: M. Gorky and Screenwriter A.S. Voznesensky (Based on New Materials from the IWL RAS Archives)
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Plotnikova Anastasia G.
Published: April 2024

The paper deals with the history of the relationship between the bright representative of the Silver Age, the writer A. S. Voznesensky and M. Gorky. The investigation is based on new archival materials from A.M. Gorky Institute of World Literature of the Russian Academy of Science. The life trajectories of Gorky and Voznesensky often went in parallel, since they were people of similar beliefs and the same social circle. We know about only one their meeting, which happened in Moscow in 1902, but their connection was carried out through letters and mutual acquaintances. Five letters of Voznesensky, stored in the archives of the Institute of World Literature of the Russian Academy of Sciences, cover the period from 1910 to 1936. In his letters, Voznesensky talks about himself, about the difficult situation of Soviet writers and the tragic fate of the writer Andrei Sobol. Gorky, in a letter dated as of 1910, gives an assessment of the previously unknown play by A.S. Voznesensky. These materials are shedding light on some facts of M. Gorky’s biography and allow for the fuller covering of the life and creative path of A.S. Voznesensky and for a deeper understanding of the literary process of the first third of the twentieth century in general.
Feminine and Masculine Images in Stories by N.A. Krasheninnikov
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Kaplun Marianna V.
Published: April 2024

The paper examines a collection of short stories by the Russian writer Nikolai Alexandrovich Krasheninnikov (1878–1941) Shadows of Love, which was published in 1915. According to critics, in his stories Krasheninnikov draws the “dreary path” of heroes who come to life at the moment of meeting with deceptive illusions. The collection’s author builds a whole system of male and female perception of relationships, using a fairly simple formula, characteristic of modernist works in which the hero or heroine is tested by betrayal or jealousy. According to Krasheninnikov, both a woman and a man who find themselves in a situation of adultery exist in an active-passive Vestnik slavianskikh kul’tur. 2024. Vol. 71 Philological sciences 167 paradigm of dependence on invented relationships (both the traitor and the one who is being cheated, and active principle can awaken in a woman, and passive becomes a companion of a man, depending on the chosen role. It is noteworthy that for a woman in Krasheninnikov’s stories, adultery is seen, first of all, as one of the manifestations of female rebellion in a patriarchal society, even if marital relations are not abusive for a woman. Opened betrayal or suspicion of it destroys masculine perception of the world, no matter how it was created, through a priori unequal marriage or loving relationships. The motif of adultery yields to the theme of a man’s search for illusory love, both in the opening and closing story of the cycle, which indicates the desire of author to both find one’s way to the essence of intersexual relations and catch the elusive “mood of love” with one stroke, which is typical for a short story genre (collection dedicated to A.P. Chekhov). The Poetics of the stories is built not so much on the antithesis of the manifestation of feminine and masculine principles, but on a preliminary attempt to reveal the psychology of sex, continued by the author in the novels of the 1910–1920s.
Private Museum in the Space of Culture: Issues of Definition and Statistics
Authors:   Russian Research D.S. Likhachev Institute of Cultural and Natural Heritage, Yureneva Tamara Yu.
Published: April 2024

Private museums play an important role in the modern cultural space of Russia; their activities make a significant contribution to the preservation and actualization of cultural heritage. The study of private museums as a special typological group that developed in the post-Soviet period has a number of terminological and statistical issues. In the context of the legal insecurity of the name “museum” and the lack of licensing of museum activities, many private organizations call themselves museums, but at the same time they do not meet the definition of a museum in the Russian legislation and the definition of the International Council of Museums (ICOM). Despite carrying out some functions of a museum and practicing some types of activities characteristic of museums, they are not museums, but museum-type institutions — creative workshops, recreational or play centers, shops, etc. There is no term “private museum” in the legislation, and the measurement uncertainty of this category of institutions remains in the statistics. An analysis of the statistical reports of a number of European countries shows that the category of “private museum” in different countries has different content. In Russia, due to the peculiarities of conducting statistical monitoring of the museum sphere, private museums are not taken into account by means of state statistics. The problem of terminological uncertainty of a private museum also exists in museology: there is no single interpretation of this group of institutions, and its specific features and essential characteristics need further study and definition.
Specifics of Renovation of the Temple and Manor Complexes (by the Example of the Smolensk and Lipetsk Regions)
Authors:   Plekhanov Russian University of Economics, Reshetova Margarita V. , Kantaryuk Ekaterina A. ,   Lipetsk State Technical University, Kantaryuk Mark V. ,   The Cosmo-Damianov Church Kazinka of the Gryazinsky Deanery of the Lipetsk Diocese, Kantaryuk Gleb V. ,   Lipetsk State Technical University
Published: April 2024

The issues of creating an integral space for the life of an extremely complex, contradictory modern person as a unique personality, with all the complex of his mental and spiritual components, brings to the fore the issue of emotional comfort. Achieving the harmony of the individual and the microcosm of the environment of his daily habitation passes into the plane of artistic and aesthetic searches and solutions. The relevance of the study lies in identifying the principles of designing a modern spiritual, cultural and socio-psychological space, where the formation and development of a new personality takes place. Currently, this issue is of special relevance for design education. The methodological basis of the research consists of general scientific methods (dialectical-materialistic method, induction, deduction, analysis, synthesis) and the method of comparative analysis. The novelty of the work is revealed in a creative approach to the environment. Basing on the analysis of architectural forms and the natural environment, the authors establish compositional techniques for the relationship between artificial and natural elements of temple complexes and estate territories. The paper highlights modern cultural and humanistic functions in the environment of temple and estate complexes as places of concentration of new spiritual and moral values of a person. The conclusions include providing techniques for harmonizing the artificial and natural objects of temples and estate complexes. The cultural and semantic unity of architectural objects, small architectural forms and open spaces shapes the artistic and figurative environment of the complex. The study represents compositional solutions in the form of the relationship of point, linear, planar and volumetric elements of the environment of multifunctional environmental complexes (by the example of the renovation projects of the Aleksino estate (Smolensk region) and the Kosmo-Damianovskiy temple in the village of Kazinka (Lipetsk region)).
Labor in the Practice of Hesychasm in Ancient Rus`
Authors:   Industrial University of Tyumen, Sarpova Olga V.
Published: April 2024

In the context of “fluid modernity”, one may perceive a need to preserve and protect basic patterns, with the labor playing an important role. Each culture develops and substantiates its own attitude towards work. Hesychasm has been the spiritual foundation of Russian society since the time of Sergius of Radonezh. As a consequence, in the spiritual practice of hesychasm physical work was an essential part of the life of hesychast monks. Studying the Legends of Old Russian Saints and the charters of coenobitic monasteries shows that the Old Russian monasticism had embraced the Doctrine of St. Gregory Palamas about unity of spiritual and bodily in man's earthly life and the possibility of cleansing the body from sin as a basis. In the praxis of Russian hesychasm, spiritual labor was inseparable from physical labor, which did not contradict the practice of internal doing, but always closely accompanied and supplemented it. The soul and body worked tied together. Since spiritual labor was complex and difficult, the physical labor of a monk was meant to be no less difficult. In order to ordeal themselves, the hesychast monks left the livable conditions of monasteries for alienation of the north-east of Rus', and thus found themselves in more severe conditions where only intense physical labor ensured their survival. The soul was solidified through hard work. The strengthened soul, in turn, became the basis for overcoming the trials chosen by the monk and achieving the goal of unity with God in earthly life.
Rural Shrines: Votive Crosses of Mezen
Authors:   N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences, Permilovskaya Anna B.
Published: April 2024

Wooden architecture is a special, independent direction of The Russian traditional construction. Its unique quality and diversity are represented in Russia, which has always been a “forest, taiga” country. This truly is a national architecture, that had absorbed the mythopoetic and Christian worldview of the people. The history of Russian wooden architecture is largely the history of wooden architecture in the Russian North. The subject of this study is the peasant rural sacral objects: votive crosses of the Mezen`, one of the most severe regions of the Russian North. The author relies on several sources: field materials (architectural-ethnographic expeditions), with measurements, photographic recording, and the preparation of scientific passports. As well as work with informants: collecting local narratives and legends related to the history of specific crosses, the experience of practical museumification and setting up the votive cross and the village foundation pillar in the Mezen` sector of the Museum “Malye Korely”. The paper analyzes crosses as historical, ethnographic, stavrographic sources, works of wooden architecture and woodcarving, Pomors pilot signs. The aim of the study is to determine the meaning of the cross as one of the main symbols of the Orthodoxy in the cultural landscape of the Northern and Arctic territories.
Birleşik Arap Emirlikleri Sermayesinin Ekonomi Politiği: Yatırım ve Yardım
Authors: Pulat Abdüssamet
Published: April 2024

Bu çalışma petrol geliri sayesinde yüksek miktarda sermaye birikimine sahip olan BAE (Birleşik Arap Emirlikleri)’nin sermaye gücünün politik etkinliğini incelemektedir. Körfez bölgesinin ikinci büyük ekonomisine sahip olan BAE, özellikle 2000’li yıllardan itibaren hem kendi bölgesinde hem de uluslararası alanda artan bir görünürlüğe sahiptir. Bu durum Arap Ayaklanmaları’nın ardından Ortadoğu’da yaşanan bölgesel güç mücadelesinde daha açık bir şekilde görülmüştür. Emirliklerin artan bu görünürlüğünün bir diğer tarafı ise kendi bölgesindeki ülkelerin yanı sıra dünyanın birçok ülkesine gönderdiği yardımlar ve bu ülkelerde yaptığı yatırımlardır. Makale bu iki olgudan hareketle BAE’nin yaptığı bu yatırım ve yardımların dış politikada bir araç olarak nasıl kullanıldığını ve etkinliğini araştırmaktadır. Bu doğrultuda ilk olarak söz konusu ülkenin sermayesinin en yoğunlaştığı ülke olan ABD’deki yatırımları ve bu yatırımların politik yönü incelenmektedir. İkinci kısımda ise BAE sermayesinin hem yatırım hem de yardım olarak en çok aktığı bölge olan Ortadoğu’daki politik yönü Mısır, Ürdün ve Fas üzerinden ele alınmaktadır.
A clinical analysis of clinicopathological features and prognostic factors of triple-negative breast cancer
Authors:   Department of General Surgery, Coltea clinical Hospital, Bucharest, Romania, Rajput-Anghel Oana-Adriana , Burcos Traean ,   Department of General Surgery, Coltea clinical Hospital, Bucharest, Romania,   Department of General Surgery, “Carol Davila” University, Bucharest, Romania
Published: April 2024

Objectives. The aim of this study was to explore the clinicopathological characteristics, prognostic factors, recurrence patterns and survival analysis of triple negative breast cancer patients compared to non-triple negative breast cancer patients. Materials and methods. The cohort included 420 patients who were diagnosed with breast cancer. The patients were evaluated based on the molecular classification and grouped into TNBC and non-TNBC. Data was explored using SPSS Version 29.0.0.0. Patient and tumor characteristics were studied. Univariate and multivariate Cox Regression was used to analyze prognostic factors. Kaplan Meier method with the log-rank test was performed to observe DFS and OS. Outcomes. The triple negative subtype was observed in 57(13.6%) patients. Patients with TNBC had a greater proportion of grade 3 tumors compared to those with non-TNBC (43.9% vs. 5.5%, p<.001). In the univariate analysis pathological type, tumor size, tumor grade, nodal invasion, lymphovascular invasion, perineural invasion and extra-nodal extension were identified as statistically significant prognostic factors. The mean time to relapse for TNBC was lower 60.0 (95% CI, 37.16 to 82.83) compared to the non-TNBC group with a mean time to relapse of 72.0 months (95% CI, 55.81 to 88.18), nevertheless distributions were not statistically significant X2(1)=1.524, p.217. Mean overall survival was 80.53 months (95% CI, 77.75 to 83.32) in non-TNBC compared to TNBC of 80.04 month (95% CI, 66.76 to 93.33) with a non-statistically significantly Log rank test X2(1)=1.252, p.263. Conclusions. Triple negative breast cancer represents a heterogenous molecular and prognostic group of tumors which needs further clinical trials in order to develop targeted therapies.
Rethinking antipsychotic use in dementia: a literature review on efficacy, safety, and alternatives
Authors:   Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia, Basubrain Omar Sami
Published: April 2024

Background an objectives. Dementia and its associated behavioral and psychological symptoms (BPSD) significantly impact patients’ quality of life, healthcare systems, and caregivers. Current treatments often include antipsychotic medications; however, their efficacy and safety profiles require careful evaluation. This review aimed to examine the use of antipsychotics in dementia, focusing on their role, efficacy, adverse effects, and clinical monitoring guidelines. Materials and methods. We conducted a thorough literature review in PubMed and Medline databases, using search terms like “dementia”, “BPSD”, “antipsychotics”, “adverse effects”, and “clinical guidelines”. Our analysis encompassed a range of research studies, including meta-analyses, randomized controlled trials, observational studies, and clinical practice guidelines. Results. While antipsychotics can be effective in managing severe BPSD symptoms like agitation and psychosis, their use carries an increased risk of mortality, stroke, and other adverse effects. Therefore, strict adherence to clinical guidelines and close monitoring are crucial to minimize these risks. Importantly, non-pharmacological interventions should always be the first-line treatment for BPSD whenever possible. Conclusions. Antipsychotics may be necessary for severe BPSD when nonpharmacological approaches are insufficient. Clinicians must carefully weigh the potential benefits against significant risks, utilizing the lowest effective doses, strict monitoring protocols, and considering alternative pharmacological options when possible. Unveiling safer and more specific BPSD treatments is a critical area for continued research.
Influence of variants mutations on the progression and outcome of COVID-19 in Pakistan
Authors: Khan Dr. Fahim Ullah , Osama Alam  , Fahim Ullah Khan  , Autif Hussain Mangi  , Mir Sadiq Shah  , Saira Abbas  , Surayia Shahab Rani  , Jalander Shah  , Yafes Ali Shah  , Shanab Ali Shah  , Muhammad Yasir Shah  , Naveed Ullah Khan  , Majid Ayaz  , Muhammad Afnan Khattak  , Nasir Khan
Published: April 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the coronavirus disease 2019 pandemic (COVID-19) has put millions of people at risk in an increasing number of countries, suggesting a serious threat to global public health. The first identification in late 2019, the strain has undergone several changes that have resulted in several genetically different variations that are cause for concern. By comprising the Delta, Gamma, Beta, and Alpha variations, each of which has shown evidence of increased virulence, transmissibility, or capacity for immune evasion as compared to ancestral strains. Their advancement over ancestral strains in transmission was discovered by genomic surveillance, highlighting the vital necessity for monitoring the evolution of SARS-CoV-2. Remdesivir and other treatments showed promising results in reducing the duration of the disease; however, the development of antivirals to prevent the emergence of new variations is still an important goal. The vaccine also provides hope, although its effectiveness against new genotypes needs to be evaluated. Pakistan is also facing the implications of COVID-19. The months-long closing of colleges and universities affected education as well. As SARS-CoV-2 continues to evolve, creating efficient antiviral therapies and guaranteeing vaccination accessibility continue to be critical concerns.
Atmospheric Retrievals of the Young Giant Planet ROXs 42B b from Low- and High-resolution Spectroscopy
Authors: Inglis Julie , Wallack Nicole L. , Xuan Jerry W. , Knutson Heather A. , Chachan Yayaati , Bryan Marta L. , Bowler Brendan P. , Iyer Aishwarya , Kataria Tiffany , Benneke Björn
Published: April 2024

Previous attempts have been made to characterize the atmospheres of directly imaged planets at low resolution (R ∼ 10–100 s), but the presence of clouds has often led to degeneracies in the retrieved atmospheric abundances with cloud opacity and temperature structure that bias retrieved compositions. In this study, we perform retrievals on the ultrayoung (≲5 Myr) directly imaged planet ROXs 42B b with both a downsampled low-resolution JHK-band spectrum from Gemini/NIFS and Keck/OSIRIS, and a high-resolution K-band spectrum from pre-upgrade Keck/NIRSPAO. Using the atmospheric retrieval framework of petitRADTRANS, we analyze both data sets individually and combined. We additionally fit for the stellar abundances and other physical properties of the host stars, a young M spectral type binary, using the SPHINX model grid. We find that the measured C/O, 0.50 ± 0.05, and metallicity, [Fe/H] = −0.67 ± 0.35, for ROXs 42B b from our high-resolution spectrum agree with those of its host stars within 1σ. The retrieved parameters from the high-resolution spectrum are also independent of our choice of cloud model. In contrast, the retrieved parameters from the low-resolution spectrum show strong degeneracies between the clouds and the retrieved metallicity and temperature structure. When we retrieve both data sets together, we find that these degeneracies are reduced but not eliminated, and the final results remain highly sensitive to cloud modeling choices. We conclude that high-resolution spectroscopy offers the most promising path for reliably determining atmospheric compositions of directly imaged companions independent of their cloud properties.
Detection of an Atmospheric Outflow from the Young Hot Saturn TOI-1268b
Authors: Pérez-González Jorge , Greklek-McKeon Michael , Vissapragada Shreyas , Saidel Morgan , Knutson Heather A. , Linssen Dion , Oklopčić Antonija
Published: April 2024

Photoevaporative mass-loss rates are expected to be highest when planets are young and the host star is more active, but to date there have been relatively few measurements of mass-loss rates for young gas giant exoplanets. In this study we measure the present-day atmospheric mass-loss rate of TOI-1268b, a young (110–380 Myr) and low density (0.71

−
0.13

+
0.17

g cm−3) hot Saturn located near the upper edge of the Neptune desert. We use Palomar/WIRC to search for excess absorption in the 1083 nm helium triplet during two transits of TOI-1268b. We find that it has a larger transit depth (

0.285

−
0.050

+
0.048

%

excess) in the helium bandpass than in the TESS observations, and convert this excess absorption into a mass-loss rate by modeling the outflow as a Parker wind. Our results indicate that this planet is losing mass at a rate of

log

M

̇

=
10.2
±
0.3

g s−1 and has a thermosphere temperature of

6900

−
1200

+
1800

K. This corresponds to a predicted atmospheric lifetime much larger than 10 Gyr. Our result suggests that photoevaporation is weak in gas giant exoplanets even at early ages.
Constraints on the Evolution of the Ionizing Background and Ionizing Photon Mean Free Path at the End of Reionization
Authors: Davies Frederick B. , Bosman Sarah E. I. , Gaikwad Prakash , Nasir Fahad , Hennawi Joseph F. , Becker George D. , Haehnelt Martin G. , D’Odorico Valentina , Bischetti Manuela , Eilers Anna-Christina , Keating Laura C. , Kulkarni Girish , Lai Samuel , Mazzucchelli Chiara , Qin Yuxiang , Satyavolu Sindhu , Wang Feige , Yang Jinyi , Zhu Yongda
Published: April 2024

The variations in Lyα forest opacity observed at z > 5.3 between lines of sight to different background quasars are too strong to be caused by fluctuations in the density field alone. The leading hypothesis for the cause of this excess variance is a late, ongoing reionization process at redshifts below six. Another model proposes strong ionizing background fluctuations coupled to a short, spatially varying mean free path of ionizing photons, without explicitly invoking incomplete reionization. With recent observations suggesting a short mean free path at z ∼ 6, and a dramatic improvement in z > 5 Lyα forest data quality, we revisit this latter possibility. Here, we apply the likelihood-free inference technique of approximate Bayesian computation (ABC) to jointly constrain the hydrogen photoionization rate ΓHI and the mean free path of ionizing photons λ
mfp from the effective optical depth distributions at z = 5.0–6.1 from XQR-30. We find that the observations are well-described by fluctuating mean free path models with average mean free paths that are consistent with the steep trend implied by independent measurements at z ∼ 5–6, with a concomitant rapid evolution of the photoionization rate.
Tracing the Galactic Disk with the Kinematics of Gaia Cepheids
Authors: Zhou Xiaoyue , Chen Xiaodian , Deng Licai , Wang Shu
Published: April 2024

Classical Cepheids (CCs) are excellent tracers for understanding the structure of the Milky Way disk. The latest Gaia Data Release 3 provides a large number of line-of-sight velocity information for Galactic CCs, offering an opportunity for studying the kinematics of the Milky Way. We determine the 3D velocities of 2057 CCs relative to the Galactic center. From the projections of the 3D velocities onto the X–Y plane of the Galactic disk, we find that the V

R
and V

ϕ
velocities of the northern and southern warps (directions with highest amplitude) are different. This phenomenon may be related to warp precession or asymmetry in warp structure. By investigating the kinematic warp model, we find that the vertical velocities of CCs are more suitable for constraining the warp precession rate than the line-of-node angle. Our results suggest that CCs at 12–14 kpc are the best sample for determining the Galactic warp precession rate. Based on the spatial structure parameters of Cepheid warp from Chen et al., we determine a warp precession rate of ω = 4.9 ± 1.6 km s−1 kpc−1 at 13 kpc, which supports a low precession rate in the warp model. In the future, more kinematic information on CCs will help to constrain the structure and evolution of the Milky Way better.
Investigating 56 High Galactic Latitude Open Cluster Candidates in
Gaia DR3
Authors: Wu You , Chen Jing , Zhang Su , Wei Xingyin , He Feilong , Zhao Yunbo , He Xuran
Published: April 2024

Using Gaia DR3 data, we revisit 56 high Galactic latitude (∣b∣ ≥ 30°) open cluster (OC) candidates with poor shapes of
color–magnitude diagrams (CMDs), including unclear and paired main sequences
(MSs). We aim to confirm their physical reality and explore whether the special
MS morphology is intrinsic to genuine OCs. Initially, we redetermine cluster
memberships by integrating five outlier detection algorithms into pyUPMASK.
However, this work fails to reproduce the 56 clusters. Instead, we find an
alternative set of 56 clusters, six of which are non-duplicates. To ascertain
whether the six clusters are real OCs, we build synthetic CMDs to derive
reliable cluster properties, including fundamental parameters, binary fraction,
and mass of the cluster. Subsequently, we investigate the structural parameters
and the age–mass and mass–radius relations of the six candidate OCs. Finally, we
utilize a multidimensional approach, incorporating cluster properties, spatial
structure, kinematic attributes, and CMD verification, to assess their physical
reality as genuine OCs further. Our results suggest that the six candidates
should be physical OCs, exhibiting well-defined CMD characteristics. Moreover,
we discover two of the six OCs as potential binary clusters.
Concise Spectrotemporal Studies of Magnetar SGR J1935+2154 Bursts
Authors: Keskin Özge , Göğüş Ersin , Kaneko Yuki , Demirer Mustafa , Yamasaki Shotaro , Baring Matthew G. , Lin Lin , Roberts Oliver J. , Kouveliotou Chryssa
Published: April 2024

SGR J1935+2154 has truly been the most prolific magnetar over the last decade: it has been entering into burst active episodes once every 1–2 yr since its discovery in 2014, it emitted the first Galactic fast radio burst associated with an X-ray burst in 2020, and it has emitted hundreds of energetic short bursts. Here, we present the time-resolved spectral analysis of 51 bright bursts from SGR J1935+2154. Unlike conventional time-resolved X-ray spectroscopic studies in the literature, we follow a two-step approach to probe true spectral evolution. For each burst, we first extract spectral information from overlapping time segments, fit them with three continuum models, and employ a machine-learning-based clustering algorithm to identify time segments that provide the largest spectral variations during each burst. We then extract spectra from those nonoverlapping (clustered) time segments and fit them again with the three models: the cutoff power-law model, the sum of two blackbody functions, and the model considering the emission of a modified blackbody undergoing resonant cyclotron scattering, which is applied systematically at this scale for the first time. Our novel technique allowed us to establish the genuine spectral evolution of magnetar bursts. We discuss the implications of our results and compare their collective behavior with the average burst properties of other magnetars.