bluuebunny/crossref_metadata_2025 huggingface dataset:
TRATAMENTO DE PERFURAÇÃO RADICULAR ASSOCIADA A FRATURA DE LIMA: RELATO DE CASO
Authors: Lima Raniely Almeida , Braga Thayris Thauany Santos , Cavalcante Amanda Vitória Sousa , Junior Adail Rosa Alvarenga
Published: August 2024

A endodontia é uma especialidade da odontologia que busca promover a descontaminação dos canais radiculares, tratando as patologias que acometem a região do periápice. Nos últimos anos apresentou um grande avanço, já que foram desenvolvidas diversas tecnologias que possuem o objetivo de facilitar e otimizar o tratamento endodôntico, entretanto, apesar dos novos instrumentos ainda ocorrem acidentes que podem interferir no sucesso do tratamento endodôntico, como a perfuração radicular e a fratura de instrumentos no interior dos canais radiculares. O objetivo deste trabalho é relatar um caso clínico de uma paciente que buscou atendimento odontológico devido a fratura de lima e perfuração do assoalho da câmara pulpar durante a realização de tratamento endodôntico.
Uso de Netacad en Bogotá: incidencia tecnológica y evaluativa como modelo de aprendizaje
Authors: Ospina Beltrán Jorge Eduardo , Colmenero Fonseca Fabiola
Published: August 2024

Netacad en Bogotá como un modelo de aprendizaje, centrándose en su incidencia tecnológica y evaluativa. Netacad, una plataforma educativa en línea se ha implementado como una herramienta integral para potenciar el aprendizaje en entornos educativos de la ciudad, la investigación se enfoca en evaluar cómo esta tecnología influye en la enseñanza y el rendimiento de los estudiantes, se analizan aspectos tecnológicos, como la accesibilidad a recursos digitales, la interactividad de la plataforma y su adaptabilidad al contexto educativo de Bogotá. Además, se aborda la evaluación como componente clave, explorando cómo Netacad facilita la medición del progreso del estudiante y la efectividad del proceso de aprendizaje. Se considera la perspectiva de docentes y estudiantes en este análisis, examinando percepciones y experiencias en el uso de la plataforma. La metodología empleada corresponde a la de una investigación cualitativa, en donde se especifica la obtención de resultados descriptivos para ser analizados a la luz de la teoría y dentro del contexto de la Institución educativa distrital República de China. Adicionalmente, la investigación se puede enmarcar dentro del estudio descriptivo de caso único, dado que busca este lograr una mejor comprensión de un evento concreto y no de uno determinado que sea representativo de otros casos o que exponga un problema determinado. La muestra objeto de estudio se enfocó en los estudiantes del grado noveno de educación matriculados en la Institución educativa distrital República de China, zona urbana de Bogotá, Colombia; conformada por un total de 21 participantes de entre los 13 y 18 años. Partiendo de un estudio de innovación educativa empleando las nuevas tecnologías en comunicaciones a través de la Plataforma Netacad, el diseño metodológico es el método constructivista, aplicando como estrategia didáctica el Aprendizaje Basado en Problemas, la enseñanza para la comprensión y la adaptatividad en el aula.
Isolasi dan Identifikasi Mikroalga Sebagai Sumber Antioksidan Di Kawasan Teluk Tomini
Authors: Pakaya Mahdalena Sy. , Mustapa Mohamad Adam , Ramadhani Fika Nuzul , Papeo Dizky Ramadani Putri , Latif Multiani S. , Kongkolu Sitty Rahma Hutami
Published: August 2024

Penggunaan antioksidan sintesis seperti butil hidroksianisol (BHA) menimbulkan efek samping bersifat karsinogenik. Antioksidan merupakan senyawa yang menangkal radikal bebas, adapun sumber antioksidan alami salah satunya mikroalga. Mikroalga memiliki potensi sebagai sumber antioksidan, yang mencegah dan menghambat radikal bebas. Penelitian ini bertujuan untuk mengisolasi dan mengidentifikasi mikroalga yang berpotensi sebagai antioksidan yang berada di salah satu kawasan perairan Teluk Tomini. Penelitian ini menggunakan metode ekperimental yang dilakukan di Laboratorium Mikrobiologi Farmasi dan Laboratorium Bahan Alam Farmasi dengan teknik pengamatan morfologi secara mikroskopis untuk identifikasi, teknik pengenceran berseri untuk isolasi, dan teknik DPPH (2,2 diphenyl-1-picrylhydrazyl) untuk pengujian antioksidan yang dianalisis menggunakan spektrofotometer UV-Vis. Hasil identifikasi didapatkan 5 jenis mikroalga yang termasuk dalam kelompok alga Chlorophyta, Cyanophyta, Euglenophyta, dan Bacillariophyta. Mikroalga yang berhasil diisolasi yaitu MA1a merupakan kelompok (Chlorophyta), dan MA2a, MA3b termasuk kelompok (Cyanophyta). Hasil uji kualitatif menunjukkan hasil positif antioksidan pada ekstrak n-heksan MA1a, MA2a dan MA3b. Serta memiliki nilai aktivitas antioksidan dengan IC50 (MA1a dan MA3b) secara berturut-turut 128,15 µg/mL dan 102,50 µg/mL termasuk kategori sedang. Serta IC50 ekstrak n-heksan (MA2a) sebesar 98,51 µg/mL termasuk kategori kuat. Analisis data secara statistik uji anova dimana (p-value<0,05) menunjukkan perbedaan yang signifikan antara aktivitas antioksidan MA1a, MA2a, MA3b dan kontrol Vitamin Ca
Kedudukan Zakat Dalam Islam Perspektif al-Qur’andan Hadis
Authors: Abidin Muhamad Zainul
Published: August 2024

Abstrak: Tingginya kedudukan zakat tersebut dalam perspektif al-Qur’an dan hadis dapat dilihat dari tigal hal. (1) Zakat adalah pilar ketiga penyangga bangunan Islam setelah syahadat dan shalat. (2) Kewajiban zakat dalam Islam diketahui secara pasti dari informasi yang jelas dan tegas dalam al-Qur’an dan hadis. (3) Ancaman yang berat, baik di dunia maupun di akhirat bagi para pengemplang zakat. Penelitian ini adalah penelitian kepustakaan dengan menggunakan metode tafsir maudhu’i dan takhrij hadis. Metode tafsir maudhu’i digunakan untuk menggali informasi secara mendalam dan holistik dari al-Qur’an. Sementara metode takhrij hadis digunakan untuk mendapatkan informasi yang valid dan komprehensif dari hadis.
Abstract: The high position of the zakat in the Qur'an's perspective and the hadith can be seen from many sources. (1) Zakat is the third pillar of Islamic building support after confession and prayer. (2) The obligation of charity in Islam is well known from clear and explicit information in the Qur'an and hadith. (3) Serious threats, both in the world and in the hereafter for the zakat takers. This study is a library study using the method of maudhu’i interpretation and hadith takhrij. The maudhu'i interpretation method is used to dig deep and holistic information from the Qur'an. While the hadith method of the hadith is used to obtain valid and comprehensive information from the hadith.
Impacto da correção da hemoglobina na realização da capacidade de difusão do monóxido de carbono em laboratório de função pulmonar: uma revisão de literatura
Authors: Luis Ferreira de Souza Passos André , Silva Melo da Cruz Isabelle , Oliveira Sales Thassyo , Carlos da Silva Júnior José , Emilly Ogando de Jesus Sena Larissa , Edrei Gomes Santos Aleff , Vitor da Silva Araújo Mateus , Matias Batista Mota Filipe , Gabino de Oliveira Vinícius , Santana Santos Henriky , Alvino Fonseca de Carvalho Neto Bento , Beatriz Meneses Melo Maria
Published: August 2024

O estudo investigou o impacto da correção da hemoglobina na capacidade de difusão do monóxido de carbono (DLCO) em pacientes com diversas condições clínicas. A análise de seis estudos revelou que a correção da DLCO pela hemoglobina é crucial para uma interpretação precisa dos resultados, especialmente em pacientes anêmicos. Embora os resultados sejam consistentes, as limitações dos estudos, como o tamanho reduzido das amostras, destacam a necessidade de pesquisas mais amplas. Recomenda-se fortemente que a correção da hemoglobina seja tornada obrigatória na interpretação da DLCO, com diretrizes claras sobre o momento e as condições para a obtenção do hemograma. Essas medidas podem melhorar a qualidade dos cuidados respiratórios oferecidos aos pacientes e promover uma abordagem mais consistente e eficaz na prática clínica.
Strategi Implementasi Teknologi Informasi Manajemen Untuk Kesuksesan Bisnis
Authors: Lim Jeffry , Sebastian Sebastian , Junaidi Junaidi , Wenny Wenny , Eryc Eryc
Published: August 2024

Bisnis yang semakin berkembang di era globalisasi membutuhkan inovasi untuk bertahan. Berbagai bentuk bisnis, baik resmi maupun informal membutuhkan teknologi informasi untuk kesuksesan dalam usahanya. Tujuan penelitian ini yaitu mengidentifikasi kriteria pemilihan teknologi informasi yang tepat serta faktor-faktor penghambat dalam implementasi teknologi informasi dan strategi implementasi yang tepat. Metode yang digunakan dalam penelitian ini yaitu penelitian deskriptif. Hasil dari penelitian ini menyatakan bahwa penerapan strategi implementasi yang tepat dapat membantu bisnis untuk mencapai kesuksesan.
The Impact of Social Media on Standard Indonesian Language Competency: A Comparative Analysis Across Age and Educational Levels
Authors: Listiani Ikah , Djahadah Nurhayati , Putri Fatimah Nadia
Published: August 2024

The rapid proliferation of social media has significantly influenced the use of the Indonesian language, particularly in the erosion of standard language norms. This study investigates the impact of social media on the usage of standard Indonesian across various age groups and educational levels. Using a mixed-methods approach, data were collected through content observation on popular platforms such as Instagram, Twitter, and Facebook, complemented by in-depth interviews and a comprehensive literature review. The findings reveal a notable shift towards informal language use, characterized by slang, acronyms, and loanwords from English, particularly among younger and less-educated users. This research identifies a negative correlation between the frequency of social media usage and adherence to standard language rules, with significant variations observed across different demographics. The study also proposes strategic interventions, such as digital literacy programs, to preserve and promote the use of standard Indonesian in the digital era. These insights contribute to understanding the evolving dynamics of language in the context of social media and provide a foundation for formulating relevant language policies and educational strategies in Indonesia.
Declaration of the policies of Cell Reviews (Marseille, France) journal
Authors:   Rviews Press, Marseille, France, Sidibé Adama
Published: August 2024

Rviews Press launched Cell Reviews (Marseille, France), its first peer-reviewed journal for discussing the discoveries and achievements in life science. Cell Reviews is an Open Access journal aiming at promoting responsibility, rigor and fairness in publishing experience. Here are outline the journal aims as well as its editorial policies.
Update on Etiopathogenesis of Type 1 Diabetes (T1D): Emphasis on Part of Crosstalk of Gut Microbiome, Pancreatic Cells & Bystander Activation of Memory CD8+T Cells with Mitochondrial Melatonergic Pathway: Treatment Repercussions - A Narrative Review
Authors: Kochar Kaur Dr. Kulvinder , Nand Allahbadia Dr. Gautam , Singh Dr. Mandeep
Published: August 2024

Origin of type 1 diabetes mellitus(T1D) takes place from the incapacity of pancreatic ß cells to generate enough insulin generally as sequelae of considerable pancreatic ß cells damage. T1D gets classified as an immune modulated disease. Nevertheless, the events which guide pancreatic ß cells apoptosis still need events to be estimated, causing incapacity of avoidance of continued cellular damage. Changes in the mitochondrial working is definitely the main pathophysiological event reinforcing pancreatic ß cells depletion in T1D. Akin to numerous medical disorders, it has become attractive in T1D, the part of the gut microbiome inclusive of crosstalk of the gut bacteria with the fungal infection Candida albicans. Gut dysbiosis along with gut permeability are intricately correlated with escalated circulating lipopolysaccharide (LPS) and repressed butyrate quantities, which may work in decontrolling immune reactions and systemic mitochondrial working. Here we have reviewed the wider available outcomes of T1D pathophysiology, emphasizing the significance of mitochondrial melatonergic pathways of pancreatic ß cells in the guiding of mitochondrial impairment. The repression of mitochondrial melatonin makes pancreatic ß cells predisposed to Oxidative stress(OS ) and impaired mitophagy; minimally modulated by elimination of melatonin‘s induction of the PTEN induced kinase (PINK1) , thus repressing mitophagy and escalating autoimmune correlated major histocompatibility complex (MHC)-1. The melatonin’s immediate precursor N-acetyl serotonin (NAS), portrays a BDNF)”; simulator through the activation of the BDNF receptor TrkB. Since both full length (TrkB-FL) & truncated( TrkB-T1) possess a substantially robust part in pancreatic ß cells working and survival , NAS, portrays one more perspective of melatonergic pathways germane for pancreatic ß cells damage in T1D. Integration of the mitochondrial melatonergic pathways in T1D pathophysiology incorporates broader earlier differing outcomes over pancreatic intercellular events. The repressed Akkermansia muciniphilia, Lactobacillus johnsonii, butyrate, and shikimate pathway, inclusive of bacteriophages aid besides pancreatic ß cells apoptosis, however further to the bystander activation of CD8+T cells, that enhances effector function and avoids their thymic deselection. The gut microbiome is a significant estimator of the mitochondrial impairment guiding pancreatic ß cells elimination and autoimmune actions obtained from cytotoxic CD8+T cells. This possesses considerable future scientific work and treatment repercussions.
The DNA Phantom Effect in Medicine: Unraveling the Mysteries of Non-Physical DNA Interactions
Authors: Sai Ho Chan Dr. Willie
Published: August 2024

The understanding of DNA and its role in medicine has undergone significant advancements over the years. While the physical aspects of DNA have been extensively studied, recent research has shed light on the existence of non-physical interactions involving DNA, known as the DNA Phantom effect (1). This phenomenon challenges conventional scientific paradigms and opens up new avenues for exploring the intricacies of DNA and its potential implications in medicine. The DNA Phantom effect refers to the ability of DNA molecules to influence biological systems (2) even when physically absent. It suggests that DNA possesses an inherent non-physical property that allows it to interact with other molecules and organisms beyond the boundaries of traditional molecular biology (3). This effect has been observed in various experimental settings, including studies on water memory (4), remote healing, and the transmission of genetic information (5). One of the key areas where the DNA Phantom effect has garnered attention is in the field of water memory. Research has shown that water molecules can retain the memory of specific DNA sequences even after the physical DNA molecules have been removed (6,7). This implies that water has the the ability to store and transmit genetic information, potentially influencing biological processes. Understanding this non-physical interaction between DNA and water could have profound implications for drug development, personalised medicine, and the treatment of various diseases. Furthermore, the DNA Phantom effect has been linked to remote healing practices. Studies have demonstrated that individuals can influence the health and well-being of others through non-local interactions, suggesting that DNA may play a role in these phenomena. The mechanisms underlying these non-physical interactions are still not fully understood, but they offer a promising avenue for exploring the mind-body connection and the potential for non-invasive therapeutic interventions. Moreover, the transmission of genetic information through non-physical means has been observed in studies involving plants, bacteria, and even human cells. These findings challenges the traditional understanding of genetics, which primarily focuses on the physical transfer of DNA molecules. The non-physical interactions between DNA and its environment raise intriguing questions about the nature of genetic inheritance and the potential for non-genetic factors to influence gene expression. While the DNA Phantom effect holds great promise for advancing our understanding of DNA and its role in medicine, it also raises skepticism and controversy within the scientific community. Critics argue that the observed effects may be attributed to experimental artifacts or uncontrolled variables. However, proponents of the DNA Phantom effect emphasize the need for further research and exploration to fully comprehend the underlying mechanisms and potential applications.
Cumulative Sum Analysis for Spinal Blockade in Novices
Authors: Ventour Dr. Dale , Thannoo Geosanne
Published: August 2024

Objectives: To create CUSUM learning curves for spinal blockade in novices with less than 3 years’ anaesthetic experience and to determine the minimal number of attempts it takes to achieve competency. Method: During the period June 2021 to March 2022, 5 trainees accomplished a total of 308 spinal blockades. Of the 308 that were done, 226 were used for data analysis as this figure had correlating data collection forms 1 and 2. (see supplementary files) CUSUM learning curves were created using acceptable and unacceptable failures rates determined from a consultant consensus (see supplementary files), and success and failure criteria were obtained from the literature. Result: 60% of trainees achieved an 85% success rate (as determined by consultant consensus) with a median of 17 spinal blockades.The true failure rate (47.5%) was higher than the acceptable failure rate (15%). Hence for 60% trainees to be deemed competent with a 52.5% success rate, 17 (15-34) spinal blockades must be performed. Conclusion: CUSUM learning curves are a useful replacement to logbooks and work based assessments in determining progress and competency of trainees. More work needs to be done to obtain failure rates of expert anaesthetists in this country, so we can define acceptable and unacceptable failure rates for our population of trainees at the various institutions. Setting such standards nationally would aid the move towards competency-based training.
Comparison between Smoking and Non-Smoking in Term of Thrombocytes Count and Coagulation: Is there any Differences?
Authors: Miftah ALgmati Aishe Abdulhafeid , Alhussin Ali Ali Abdalmawla , Ghaith Mohammed Ashraf , Salahuddin Khalifa Ali , Ahmed Mohammed Fatima , Mahjoub ALjuhaimi Fatima , Shibob Abdullah Fatima , Ramadan Farag Mohammed
Published: August 2024

Introduction: Smoking is a major risk factor for cardiovascular disease, with a significant impact on platelet activation and thrombosis. This study aims to examine the effects of smoking on platelet activation and INR as a marker of thrombosis. This study aimed to investigate the influence of tobacco smoking on platelets count and coagulation tests (PT, PTT, INR) in adult males in sirte city. Materials and Methods: A case control study was carried out during 1/1/2023 to 15/2/2023. 200 males (100 smokers and 100 non-smokers) were participated in this study. with ages between 15-85 years enrolled in this study. Data were presented in median (interquartile range). Data was collected by using structural interviewing questionnaire. blood samples were collected in tri sodium citrate anti-coagulant for PT and INR, manually analyzed was using. Ethylene-di-amine-tetra-acetic acid (EDTA) anticoagulant for the platelets count, analyzed by (Sysmex, German) automated hematology analyzer. Main Results: The results showed that the Median platelets count was statistically no significantly between smokers (237) and non-smokers (256) , U = 5.696.000 , Z = 1.701, P = 0.089. Whereas, median PT was statistically significant between smokers (15) and non-smokers (14), U = 4.112.000, Z = -2.194 , P = 0.028. Also, median INR was statistically significant between smokers (1.4) and non-smokers (1.3), U = 4.063.500, Z = -2.316 , P = 0.021. Conclusion: The present study shows that smokers likely to have lesser platelet counts , longer PT, and higher INR values in comparable to non-smokers. Thus, smoking might be related with bleeding complaints but additional examinations are required.
Does Preoperative Anemia Influences Postoperative Mortality After Isolated CABG? A Sequential Analysis
Authors: CAUS Thierry , IAICHE Toufik
Published: August 2024

The potential impact of preoperative anemia on postoperative mortality after CABG is becoming widely endorsed by best practice guidelines in patient blood management. However clinical evidences are still scarce and very large number of patients are needed to prove certainty in preemptive therapeutic measures like iron substitution. We aimed at illustrate the usefulness of CUSUM in this setting and reviewed a historical series of 1282 patients operated on for isolated CABG. The negative effect of preoperative anemia on fatal outcome after CABG could be assessed with an unacceptable rate of failure after 266 anemic patients only. This should encourage trials based on sequential analysis with the hope to fasten emergence of conclusive results.
Inkluderende litteraturundervisning
Authors: Oksbjerg Marianne , Denning Rikke Christoffersen , Carlsen Dorthe , Ipsen Max , Beermann Hanne , Liengaard Trine , Fjalland Lene Pernille
Published: August 2024

ResuméFlere undersøgelser peger på, at ikke alle elever trives fagligt i skolen. I denne artikel undersøger vi inkluderende undervisning i et fagdidaktisk perspektiv med særligt fokus på elevers oplevelse af deltagelsesmuligheder i skolens litteraturundervisning på mellemtrinnet. Vi kæder faglig trivsel sammen med elevers muligheder for faglig deltagelse i litteraturundervisning. Formålet med projektet er at generere ny viden om, hvordan elever inkluderes i faglige fællesskaber i litteraturundervisningen. I studiet tager vi udgangspunkt i den opfattelse, at alle elever bør have faglige deltagelsesmuligheder. Studiet anlægger et elevperspektiv og peger på, at udvalgte elever ser ud til i højere grad at deltage socialt end fagligt, og særligt i overgangene mellem forskellige organiseringer af undervisningen ser de ud til at mangle faglige deltagelsesmuligheder.
AbstractSeveral studies indicate that not all students in school thrive academically. Here, academic well-being is linked to students’ opportunities for academic participation in literature lessons in middle school. The purpose of the project is to generate new knowledge about how students are included in academic communities in Danish classes where teaching aids are included. The study is based on the view that all students should have opportunities for academic participation. The study takes a learner perspective and points out that selected learners seem to participate more socially than academically, and especially in the transitions between different organizations of teaching, they seem to lack academic participation opportunities.
IMPROVING PRODUCTIVITY IN AN SME IN THE METALWORKING SECTOR THROUGH LEAN MANUFACTURING AND TPM TOOLS A CASE STUDY IN PERU
Authors: Florez-Cáceres Rocio Mercedes , Huamán-Echevaría Christian Elian , Quiroz-Flores Juan Carlos
Published: August 2024

The objective of this study is to increase the efficiency and productivity of a business that offers sandblasting and painting services. An integrated model incorporating lean manufacturing tools, including preventative and autonomous maintenance, 5S, and SMED, is presented in this article. The model consists of four distinct phases. The initial stage consists of diagnosing the company’s beginning state. The second stage entails the execution of the 5S methodology to arrange workstations. Following this, a maintenance programme was implemented, which ultimately resulted in the reduction of setup times for the painting machine configuration. Furthermore, an assessment was conducted on the realised enhancements, and metrics were compared both before and after deployment. Statistical validation was performed via a pilot study that occupied an extended period. The findings validated a productivity improvement of 10% and an efficiency increase of 23.8%. In addition, a 32.04% reduction in setup time was observed.
Note from the Editor
Authors: Schutte Corne
Published: August 2024

The Southern African Institute for Industrial Engineering (SAIIE) Annual Awards ceremony was held on 14 August in Stellenbosch. Two journal-specific awards were presented at this function: 1. The SAIIE Award for the Best Industrial Engineering Paper published in the South Africa Journal of Industrial Engineering (SAJIE). This year, the best article was awarded to “The Development of an Action Priority Matrix and Technology Roadmap for the Implementation of Data Driven and Machine-Learning-Based Predictive Maintenance in the South African Railway Industry.”, authored by Lindelani Nethamba and Schalk Grobberlaar, from the Department of Engineering and Technology Management, University of Pretoria. (https://doi.org/10.7166/34-3-2958). 2. The SAJIE Editor’s Award, which was presented to Prof Tinus Pretorius (Emeritus Professor at the University of Pretoria), for his support to the journal over many years as sponsor and reviewer. Our next edition will be the special edition, where the best submissions from related conferences in South Africa are published. The review process and selection for the SAIIE conference is already completed, and we are looking forward to showcase the research and new thinking from those conferences. This edition has a total of 12 articles, with nine articles from authors with South African connections and the balance from international authors. If you have suggestions on how we can take this journal forward, please let me know. Corne Schutte Editor
La parodia de la ficción sentimental en La Celestina
Authors: Lacarra María Eugenia
Published: August 2024

No disponible.
Estudios y aplicaciones de PRESEEA. Fonética, gramática y léxico
Authors: Engra Minaya Sara , De las Fuentes Gutiérrez Elisa , Paredes García Florentino
Published: August 2024

En el presente monográfico, Estudios y aplicaciones de PRESEEA. Fonética, gramática y léxico, se ofrecen diez artículos que contienen investigaciones realizadas en el marco del macro-proyecto PRESEEA y a partir datos correspondientes a los corpus recogidos en el seno delproyecto —si bien eventualmente pueden haberse usado otras fuentes—. El volumen se compone de tres bloques. El primero está dedicado a la fonética e incluye dos trabajos, unosobre unidades segmentales y otros sobre unidades suprasegmentales. El segundo bloque se centra en aspectos de variación gramatical y se compone de cinco artículos, donde se abordantemas como el gerundio perifrástico, el sujeto pronominal, la duplicación de clíticos o lasperífrasis. El último bloque contiene tres trabajos sobre léxico, uno de ellos sobre expresionescuantificadoras, otro sobre anglicismos y un tercero sobre unidades que tienen ciertas marcaslexicográficas. Los datos y resultados que se ofrecen corresponden a ciudades ubicadas enlas dos orillas: Colombia (Barranquilla, Cartagena, Valledupar, Cali y Medellín), Cuba (LaHabana), España (Granada, Alcalá de Henares, Valencia y Palma de Mallorca) y México(Tijuana, Puebla, Mexicali y Ciudad de México).
La expresión de sujetos pronominales en el español andino colombiano: el corpus PRESEEA-Cali
Authors: Orozco Rafael , Marmolejo Caicedo Margareth , Grajales Róbinson
Published: August 2024

Este trabajo constituye un análisis preliminar de la expresión variable de sujetos pronominales (ESP) en el corpus PRESEEA-Cali, Colombia. Exploramos los efectos de cinco variables predictoras (2 sociales y 3 lingüísticas) en 4425 muestras. Los resultados revelan la tasa pronominal (29,7%) más alta encontrada en una comunidad de habla latinoamericana continental. El condicionamiento lingüístico indica que persona y número gramatical ejercen el efecto más fuerte entre los predictores explorados; específicamente uno constituye el pronombre que más favorece los sujetos expresos. El condicionamiento social descubre que las mujeres promueven los sujetos expresos, tal como ocurre en la región Caribe, pero contrario a lo encontrado en Medellín. Además, los efectos de la edad revelan que los jóvenes favorecen los sujetos tácitos y los mayores favorecen los sujetos expresos. Este hallazgo puede tener implicaciones cognitivas, puesto que se espera normalmente que los hablantes jóvenes tengan tasas pronominales más altas.
Burnout Symptoms among Millennial Teachers in India: The Efficacy of the Emotional Self-Care Online Intervention Program (ESCOIP)
Authors:   University of Santo Tomas, Manila, Philippines, Thomas Joby , Reyes Marc Eric S. ,   University of Santo Tomas, Manila, Philippines
Published: August 2024

The phenomenon of teacher burnout has gained greater attention due to its grave impact on the educational system and the well-being of teachers. In this regard, millennial teachers’ experiences— currently comprising most of the teaching workforce—have gained attention in scholarly research. Thus, developing an efficacious online intervention program is crucial to alleviate and avoid teacher burnout among millennials. This study investigated the effectiveness of the Emotional Self-Care Online Intervention Program (ESCOIP) in treating burnout symptoms among Indian millennial teachers. The present study employed Conklin’s program development model, which involves three phases: (1) planning, (2) design and implementation, and (3) evaluation and program validation. The participants were millennial teachers born between the early 1980s and mid-1990s (N =521) from Kerala, South India, and they were randomly assigned to experimental (n = 20) and control (n = 20) groups. We used the Socio-demographic survey, the Maslach Burnout Inventory-Educator survey, and the Focus Group discussions to understand the prevalence and complexities involved in this problem. Paired t-test and MANOVA were used for data analysis, and partial eta squared (η2p) measured the extent of the effect of the ESCOIP. Results of the paired t-test and MANOVA revealed a statistically significant effect. Therefore, the online intervention program's outcomes demonstrated that the ESCOIP effectively treats burnout symptoms that millennial teachers experience.
Coping with salt stress
Authors: Liang Xiaoyan , Jiang Caifu
Published: August 2024

Salt stress delays seed germination in plants by increasing the hydrolysis of arginine-derived urea.
A roadmap for empowering cardiovascular disease patients: a 5P-Medicine approach and technological integration
Authors: Denysyuk Hanna V. , Pires Ivan Miguel , Garcia Nuno M.
Published: August 2024

This article explores the multifaceted concept of cardiovascular disease (CVD) patients’ empowerment, emphasizing a shift from compliance-oriented models to active patient participation. In recognizing that cardiovascular disease is a paramount global health challenge, this study illuminates the pressing need for empowering patients, underscoring their role as active participants in their healthcare journey. Grounded in 5P-Medicine principles—Predictive, Preventive, Participatory, Personalized, and Precision Medicine—the importance of empowering CVD patients through analytics, prevention, participatory decision making, and personalized treatments is highlighted. Incorporating a comprehensive overview of patient empowerment strategies, including self-management, health literacy, patient involvement, and shared decision making, the article advocates for tailored approaches aligned with individual needs, cultural contexts, and healthcare systems. Technological integration is examined to enhance patient engagement and personalized healthcare experiences. The critical role of patient-centered design in integrating digital tools for CVD management is emphasized, ensuring successful adoption and meaningful impact on healthcare outcomes. The conclusion proposes vital research questions addressing challenges and opportunities in CVD patient empowerment. These questions stress the importance of medical community research, understanding user expectations, evaluating existing technologies, defining ideal empowerment scenarios, and conducting a literature review for informed advancements. This article lays the foundation for future research, contributing to ongoing patient-centered healthcare evolution, especially in empowering individuals with a 5P-Medicine approach to cardiovascular diseases.
Surprising diversity of new plasmids in bacteria isolated from hemorrhoid patients
Authors: Wang Yihua , Su Wenya , Zeng Xiang , Liu Zhaopeng , Zhu Jiaming , Wang Mingyu , Li Ling , Shen Wenlong
Published: August 2024

Background

Hemorrhoids are common conditions at or around the anus, to which numerous people suffer worldwide. Previous research has suggested that microbes may play a role in the development of hemorrhoids, and the origins of these microbes have been preliminarily investigated. However, no detailed research on the microbes related to hemorrhoid patients has been conducted. This work aims to provide an initial investigation into the microbes related to hemorrhoid patients with high quality whole genome sequencing.

Methods

Forty-nine bacterial strains were isolated from seven hemorrhoid patients. Third-generation nanopore sequencing was performed to obtain high quality whole genome sequences. The presence of plasmids, particularly new plasmids, along with antibiotic resistance genes, was investigated for these strains. Phylogenetic analysis and genome comparisons were performed.

Results

Out of the 31 plasmids found in the strains, 15 new plasmids that have not been observed previously were discovered. Further structural analysis revealed new multidrug-resistant conjugative plasmids, virulent plasmids, and small, high-copy mobile plasmids that may play significant functional roles. These plasmids were found to harbor numerous integrases, transposases, and recombinases, suggesting their ability to quickly obtain genes to change functions. Analysis of antibiotic resistance genes revealed the presence of antibiotic resistant-integrons. Together with the surprising number of new plasmids identified, as well as the finding of transmission and modification events for plasmids in this work, we came to the suggestion that plasmids play a major role in genetic plasticity.

Conclusion

This study reveals that the diversity of plasmids in human-associated microbes has been underestimated. With the decreasing cost of whole-genome sequencing, monitoring plasmids deserves increased attention in future surveillance efforts.
La toma de decisiones de futuros maestros de primaria al interactuar con el pensamiento algebraico de niños
Authors: Pinto Eder , Piñeiro Juan Luis , Cortés Camila , Martínez-Videla María Victoria
Published: August 2024

En esta investigación se abordó la pregunta: ¿Cómo son las decisiones de futuros profesores de primaria (FP) al considerar el pensamiento algebraico de niños de 9 años? Se partió de un tipo específico de noticing para describir las decisiones de 21 FP al observar las estrategias empleadas por 3 niños para resolver la igualdad 6+4=+5. Los FP participaron en un curso de seis sesiones sobre enseñanza y aprendizaje del álgebra basado en el análisis de videos como vía para aproximarse a la práctica docente. Centrándose en las sesiones 1 y 2, se examinaron las respuestas escritas de los FP ante dos situaciones distintas. Los principales resultados muestran que, aunque las decisiones de los FP a menudo carecían de evidencias, sus razonamientos coincidían con aspectos específicos del pensamiento algebraico y la investigación tratada durante el curso. Finalmente, se identificaron dos posturas adoptadas por los FP al decidir: a) aritmética, centrada en los cálculos que deben seguir los niños, y b) relacional, enfocada en la relación de operaciones mediante el signo igual. Se discutió sobre el rol del noticing y el análisis de videos como herramientas para aproximar a FP a la práctica de enseñar álgebra en la educación primaria.
Oportunidades de aprendizaje de la práctica pedagógica en el campus universitario: planificación, ejecución y contribución en la formación profesional de futuros docentes
Authors: Matsumoto-Royo Kiomi , Conget Paulette
Published: August 2024

La formación inicial docente busca enseñar a enseñar. Para ello, se ha propuesto que los programas incorporen formalmente instancias de comprensión y entrenamiento en prácticas pedagógicas, tanto en las asignaturas como en terreno. Este estudio tiene como objetivo explorar la planificación, ejecución y contribución a la formación profesional de la incorporación de oportunidades de aprendizaje de la práctica pedagógica (OAP) en asignaturas impartidas en el campus universitario. Para ello, se realizó un estudio descriptivo en tres programas de formación docente: educación de párvulos, básica y media. Primero, se identificaron las OAP planificadas analizando las calendarizaciones de 72 asignaturas. Luego, se examinó la percepción al respecto de las OAP ejecutadas encuestando a 231docentes en formación. Finalmente, se indagó sobre la contribución de las OAP a la formación profesional entrevistando a 8 docentes en formación. Las OAP más planificadas por los formadores de docentes fueron planificar experiencias de aprendizaje y simular lo que hace un docente durante una experiencia de aprendizaje. Esta última fue la OAP más frecuentemente ejecutada por los docentes en formación, quienes reconocen que las simulaciones les permiten: 1) aplicar los contenidos, 2) aprender de los errores, 3) ejercitar el monitoreo metacognitivo y la autoevaluación y 4) aproximarse a la complejidad de la enseñanza. Los hallazgos de esta investigación pueden ser utilizados por las instituciones formadoras para fundamentar la incorporación y diseñar la implementación de la enseñanza de las OAP desde el primer año del trayecto formativo, haciendo un énfasis particular en la simulación de lo que hace un docente antes y durante una experiencia de aprendizaje.
Contrastando las expectativas de supervisores y docentes de aula respecto a sus funciones en la formación práctica de estudiantes de pedagogía
Authors: Montecinos Carmen
Published: August 2024

Las políticas de formación inicial del profesorado han buscado reforzar el componente práctico requiriendo a las universidades aumentar las actividades curriculares y establecer convenios con centros educativos. El objetivo de este estudio es analizar cómo los docentes universitarios y docentes de aula (tutores) entienden sus funciones al acompañar a docentes en formación que se encuentran realizando una asignatura de práctica en un centro educativo. En una primera etapa, se aplicó un cuestionario a 56 supervisores de práctica de 5 universidades chilenas (13 programas) y a 540 profesores tutores de 91 establecimientos que eran centros de práctica de esos programas. En la segunda etapa, se exploraron las perspectivas de los tutores a través de 12 entrevistas grupales. Los resultados muestran que hay más acuerdo que desacuerdo sobre las funciones de cada uno y cierta superposición, sin coordinación, en las funciones de estos dos actores. Más bien, se observan diferencias con relación a las prioridades en su trabajo con practicantes. Mientras que para los supervisores su función más importante es proporcionar a los practicantes herramientas teóricas para cumplir con las tareas contempladas para la asignatura de práctica, para los tutores lo principal es que los supervisores asistan a los centros de práctica para apoyar el desempeño de los practicantes y el trabajo de los tutores. Estas diferencias generan algunas tensiones, cuya resolución implica atender problemas estructurales relacionados con la falta de bidireccionalidad en las alianzas universidad-sistema escolar para la tarea compartida de preparar a la próxima generación de docentes. Por tanto, se sugiere avanzar en la construcción de significados, propósitos y prácticas compartidas que sustenten una colaboración auténtica y de impacto positivo en los centros de práctica, las carreras de pedagogía y sus estudiantes.
A Case Report on Management of Paraquat Poisoning Associated with Oral Fibrosis and Lung Fibrosis
Authors: Karthick P , Arun E , Nandakumar R , Sarumathy S
Published: August 2024

Paraquat, a brown, viscous liquid herbicide known as “N, N’-dimethyl-4,4’-bipyridinium dichloride,” rapidly deactivates upon contact with soil, making it an efficient herbicide with minimal chronic toxicity. However, the prognosis is poor for acute poisoning or high doses of paraquat. Since, there is currently no effective treatment for paraquat poisoning, preventative efforts must be prioritised. A 31-year-old male patient was brought to the Emergency Department after ingesting around 10 mL of paraquat while under the influence of alcohol. He complained of vomiting, throat pain, mouth ulcers, and difficulty swallowing and speaking. Upon oral examination, erosions were observed on the upper and lower lips, with erythema present on the tongue. The patient was diagnosed with deliberate self-harm paraquat poisoning-induced oral fibrosis. Computed Tomography (CT) chest scan revealed no fibrosis except for a few paraseptal emphysematous changes in the apical segments of the bilateral upper lobes. Gastric lavage was performed, and activated charcoal (60 mg) was administered as initial treatment. The patient was then treated with choline salicylate gel, dexamethasone, and acetylcysteine as an anti-inflammatory measure for oral fibrosis before being discharged. However, the patient returned with complaints of dysphagia, worsened oral ulcers, and an inability to take oral fluids, leading to readmission for these issues. A follow-up CT chest scan revealed patchy ground glass consolidatory changes with surrounding minimal fibrotic changes in the bilateral upper lobe. The patient exhibited elevated levels of White Blood Cells (WBC), neutrophils, Erythrocyte Sedimentation Rate (ESR), urea, Blood Urea Nitrogen (BUN), and C-reactive Protein (CRP), which were continuously monitored. Due to the oral ulcers and lung fibrosis, the patient was treated with methylprednisolone, acetylcysteine, povidone iodine mouthwash, and clotrimazole mouth paint. The patient was managed conservatively, and there was an improvement in symptoms.
Studies of Nodules and Productivity with Phosphate and Zinc Solubilizing Microbes in Lentil
Authors: Yaying Monica , Shukla Anil , Supriya  , Singh Shobhana , Choudhary Lachha , Tomar Manish
Published: August 2024

A field experiment was conducted at GB Pant University of Agriculture and Technology, Pantnagar during Rabi 2020 on Phosphorus and Zinc efficacy with phosphate and zinc solubilizing microbes in lentil (Lens culinaris) in tarai region. Twelve different doses of phosphorus and zinc with phosphate and zinc solubilizing microbes  viz. T1: Absolute Control (without P and Zn), T2: RDP@ 48 kg ha-1, T3: Soil application of ZnSO4@ 25 kg ha-1, T4: Biophos @ 5ml kg-1 seed, T5: Biozinc (5 ml kg-1 seed), T6: Biophos and Biozinc (5 ml kg-1 seed), T7: 50% RDP @ 24 kg + Biophos (5 ml kg-1 seed), T8: 12.5 kg ZnSO4 + Biozinc (5 ml kg-1 seed), T9: 50% RDP@ 24 kg + Biophos + Biozinc (5 ml kg-1 seed), T10: 50% recommended phosphorus dose application @ 24 kgha-1 + Biophos @ 5 ml seed-1 + Biozinc @ 5 ml kg-1 seed, T11: Recommended phosphorus dose application @ 48 kg ha-1 + nutrient mobilizer (LNm 43a) @ 20 g kg-1 seed and T12: 50% recommended phosphorus dose application @ 24 kg ha-1 + Soil application of 12.5 kg ZnSO4 ha-1 + nutrient mobilize @ 20g kg-1 seed were tested in randomized block design taking three replications. Results showed that the number and dry weight of nodules and grain yield found highest in treatment 50% RDP @ 24 +12.5 kg ZnSO4 + Biophos + Biozinc (5 ml seed-1 each) whereas treatment 12.5 kg ZnSO4 + Biozinc (5 mleed-1) showed highest harvest index compared to control.
Hydrogeochemical Characterization and Multivariate Analysis of Groundwater in Pala, Burkina Faso: Implications for Sustainable Water Management
Authors: Millogo Césard , Bakouan Corneille , Sako Aboubakar , Nakolendoussé Samuel
Published: August 2024

The quality of groundwater and spring water in the Pala locality, influenced by both natural processes and human activities, is a major issue in the supply of drinking water to the city of Bobo Dioulasso. The geological context is mainly composed of Sotouba sandstone. This influences the chemical composition of the aquifers through water-rock interaction. This study examines the hydrogeochemical characteristics of the region's water resources in order to shed light on sustainable management strategies. For this fact, physico-chemical parameters of rainwater, and existing springs and boreholes were analysed in accordance with current standards. Statistical methods including correlation analysis, principal component analysis (PCA), factor analysis (FA) and hierarchical clustering (HCA) were used for interpretation. The results indicate that spring water is less mineralised than borehole water, which shows greater variability in physical and chemical parameters such as pH, electrical conductivity (EC) and turbidity. Major ions, dominated by bicarbonates and calcium, influence the main water facies, which are calcic bicarbonate and calcic and magnesian bicarbonate. Analysis of heavy metals reveals concentrations below WHO standards. The PCA identifies the dominant factors influencing water chemistry.  Factor analysis highlights the significant contributions of ions and the importance of understanding hydrogeochemical processes. At present, the spring and borehole water in the study area is fit for drinking in terms of physico-chemical properties and metals in the parameters analysed. Recommendations include the establishment of monitoring frameworks to protect water quality from potential sources of pollution, underlining the need for proactive management strategies in the region.
Assessment of Small Object Detection Algorithm Based on Improved YOLOv5s
Authors: Meng Jintao , Shen Shaokai
Published: August 2024

The YOLOv5 algorithm is widely used in object detection due to its efficient inference speed and high accuracy. However, it still faces challenges in small object detection. This paper proposes a series of improvements, including the addition of small object detection layers, the integration of the CBAM attention mechanism, and the optimization of the loss function by introducing EIoU, to enhance the model's feature extraction capability and detection accuracy. First, the paper enhances the network's perception of small objects by adding pyramid low-level semantic layers and constructing new small object detection heads. Second, the CBAM module is integrated into the C3 module, improving the model's feature representation ability and effectively preventing information loss. Finally, by introducing the EIoU loss function, the quality contribution of anchor boxes is enhanced, improving the model's detection accuracy and regression speed. Experimental results show that the improved YOLOv5 algorithm performs excellently on the BDD100K dataset, especially in small object detection. Compared with the original algorithm, it shows improvements in detection accuracy, recall rate, and mean average precision (mAP), despite the slight increase in parameters and computation, it still meets real-time requirements. This research provides strong support for further enhancing small object detection in autonomous driving scenarios.