bluuebunny/crossref_metadata_2025 huggingface dataset:
The correlation of blood pressure changes and cardiac morpho- functional restructuring in young athletes
Authors: Balykova L. A. , Glotov A. S. , Ivyansky S. A. , Shirokova A. A , Soldatov O. M. , Grishutkina I. A. , Varlashina K. A. , Krasnopolskaya A. V.
Published: May 2020

A steady increase in the number of young sportsmen predetermines the relevance of studying the nature and severity of cardiovascular system remodeling in young athletes, including the development of arterial hypertension (AH) and left ventricular myocardial hypertrophy (LVHM).

Objective. To study the prevalence and nature of arterial hypertension (AH) and its associations with signs of cardiovascular remodeling in young athletes taking into account pathogenetic relationship and genetic determination.

Characteristics of children and methods. The study included 80 young athletes (including 42 boys, average age 14,5±1,54 years), divided into 4 groups depending on the kind of sports (1 – cyclic, 2 – game, 3 – complex coordination, 4 – power). We used the following research methods: “office” (i.e. during visit to the doctor) measurement of blood pressure, electrocardiography, echocardiography, color Doppler scanning of the neck vessels, daily monitoring of blood pressure, bicycle ergometry, genetic testing using the original panel with 448 markers.

Results. An increase in blood pressure at rest was detected in 2,5% of children engaged in power sports, an insufficient decrease at night – in 16,3% of children, and an excessive reaction of blood pressure to dosed physical activity – in 25% of children. These changes correlated with signs of sports remodeling, in particular with the formation of left ventricular myocardial hypertrophy, which was diagnosed in 7–12,5% of athletes. According to the results of genetic testing, pronounced polymorphism in the NO synthase gene at three loci (rs10918594, rs12143842, rs16847548) was associated with a reorganization of the cardiovascular system in 45% of athletes.

Conclusion. Violation of the circadian profile of blood pressure and excessive reaction to physical activity demonstrate 7,5–25% of young athletes, especially those involved in complex coordination and power sports. These changes were associated with the severity of sports remodeling and determined by a genetic predisposition.
Clinical and X-ray diagnostic criteria for maxillofacial damage in children with juvenile limited scleroderma
Authors: Skakodub A. A. , Geppe N. А. , Admakin O. I. , Chepurnova E. S. , Mamedov A. A. , Podchernyaeva N. S. , Chebysheva S. N. , Kharke V. V. , Dudnik O. V. , Radenska-Lopovok S. G.
Published: May 2020

The objective of our study was to improve the diagnosis of maxillofacial lesions in children with juvenile scleroderma. We performed a dental examination of 41 children from 4 to 17 years old with juvenile scleroderma. Based on the clinical X-ray examination we identified the main diagnostic signs of the maxillofacial damage in children with juvenile scleroderma, including partial hemiatrophy, plaque or linear facial lesions, reduced salivation, atrophic glossitis, plaque spots of mucous tongue atrophy, ischemia or shortening of the sublingual bridle, local recession of the gums of the lower jaw, dystopia and tooth supraposition, disocclusion, delay teething, spontaneous resorption of the permanent teeth roots, one-sided delay in the development of jaw bones. Using this complex of symptoms a dentist at the first visit can pre-diagnose scleroderma, which is especially important for the selection of adequate methods of treatment and prevention.
Financial evaluation of Tadawul All Share Index (TASI) listed stocks using Capital Asset Pricing Model
Authors: Vinodkumar Nisa , Khalid AlJasser Hadeel
Published: May 2020

The Kingdom of Saudi Arabia is strongly committed to stimulating savings culture in the local community by providing financial literacy in financial planning, investments, and budgeting. Inculcating the savings and investment behavior among the people will help materialize one of the elements of Saudi Vision 2030. Tadawul, being the most liquid stock market in the Middle East and North Africa, offers investors the ability to grow their capital with confidence through facilitating trading in different securities such as equities, debt instruments, and Exchange Traded Funds (ETFs). There is a great scope for investors to invest in the companies listed in Tadawul All Share Index (TASI) due to its strong economic fundamentals. The present study aims to apply the CAPM in Tadawul listed stocks, which will help in understanding the systematic and unsystematic risk associated with stocks, understanding their actual and theoretical return on stocks. The methodology adopted is the analysis of secondary data for all listed stocks in Tadawul using the Bloomberg terminal. The financial valuation includes elements like beta, alpha, correlation and standard deviation, expected return and actual return. The practical value obtained from the study will help investors go for undervalued stocks with lower beta, higher expected annual return, and lower systematic risks. Thus, the result shows the predicting power in KSA market and the scope for long-term investments by the investors to boost their savings and investment behavior and materialize one element of Vision 2030.
AcknowledgmentThis research was funded by the Deanship of Scientific Research at Princess Nourah bint Abdulrahman University through the Fast-Track Research Funding Program.
The role of moderating audit quality relationship between corporate characteristics and financial distress in the Indonesian mining sector
Authors: Wahyu Santosa Perdana , Eliakim Tambunan Martua , Rohima Kumullah Eva
Published: May 2020

Financial performance and corporate governance play an important role in financial distress in the mining sector, which is one of the most significant contributors to the Indonesian economy. This study aims to analyze the effect of corporate characteristics on financial distress (FD), which is moderated by corporate governance (audit quality), and uses the controlling variables (inflation rate and GDP). The study uses data from audited financial statements from mining sector in the Indonesia Stock Exchange for the period 2013–2018. Since the dependent variable (FD) is dichotomous, this study used a binary logistic regression model, as it is the case in many studies regarding the probability of bankruptcy filing. In line with the current study and some previous studies, leverage, efficiency (activity), market-to-book value, audit quality, and GDP affect the probability of financial distress significantly. Only liquidity and inflation do not impact FD. Besides, the moderating audit quality weakens the effect of liquidity and PBV; otherwise, it strengthens leverage and efficiency in predicting financial distress. As for managerial implications, this study concludes that corporate performance, corporate governance, and macro-risk factors affect the probability of financial distress. The authors suggest that mining firms need to pay attention to corporate governance and should watch the economic condition for business sustainability.
Balanced scorecard for implementing united territorial communities’ social responsibility
Authors: Pylypiv Nadia , Piatnychuk Iryna , Halachenko Oleksandr , Maksymiv Yuliia , Popadynets Nazariy
Published: May 2020

Under decentralization, local governments gain more rights and opportunities to use various types of resources, thus, increasing their level of responsibility (including social responsibility) for the use of resources. The paper aims to reveal the consequences of decentralization reform for the indicators of united territorial communities (UTCs) budgeting that reflect their general socio-economic condition, as well as the nature of the latter one; to adapt the balanced scorecard (BSC) to the feature of UTCs’ functioning, and to develop the UTCs strategic map. The paper indicates that the system of balanced indicators is an analytical tool for ensuring the realization of the concept of social responsibility of the UТСs. The research resulted in the development of the balanced scorecard of indicators for UTCs. It includes the following blocks: internal business processes, funding, service providers, service consumers, and environment. The research contributed to the development of UTCs strategic map based on BSC adapted to the peculiarities of UTCs. The strategic map provides an opportunity to link strategic goals of UTCs with the developed BSC blocks and allows for a successful implementation of the concept of UTCs’ social responsibility in conditions of the need to achieve sustainable development.
A EXPERIÊNCIA DO NEXT NOS SEUS OITO ANOS DE ATIVIDADES DESENVOLVIDAS COM O JOGO DE XADREZ NA UNIVERSIDADE
Authors: Pereira Kariston , Pavanati Iandra
Published: May 2020

O NexT (Núcleo de Estudos em Xadrez & Tecnologias) visa proporcionar à comunidade a oportunidade de aprender, praticar, treinar, competir, estudar e pesquisar o xadrez e suas tecnologias dentro da Universidade do Estado de Santa Catarina - UDESC. Na busca desse objetivo, o NexT tem desenvolvido diversas ações de ensino, pesquisa e extensão deste 2011. Entre elas destacam-se o Projeto “Sextas Xadrez na Universidade”, com o desenvolvimento de oficinas lúdico-didáticas orientadas de xadrez, para propiciar a integração dos participantes e possibilitar a troca de experiências entre os mesmos e o Projeto “Torneios de Xadrez na Universidade”, com a realização de competições e treinamentos entre os membros e potenciais membros do NexT. Vinculadas a este projeto, o NexT também desenvolve competições seletivas para os Jogos de Integração dos Acadêmicos da UDESC (JIUDESC), bem como a preparação dos atletas selecionados. Outro projeto de grande importância no NexT é o Projeto “Cursos de Xadrez na Universidade” que, a cada ano, conduz duas turmas no curso de xadrez de nível básico, permitindo aos aprendizes o acesso ao conhecimento enxadrístico elementar e também duas turmas do curso de nível intermediário, alternando temas como fundamentos de finais, tática, estratégia e aberturas.  Na pesquisa, o NexT já orientou trabalhos na Graduação e Dissertações de Mestrado. Vale também salientar conquistas tanto internas como nacionais do NexT enquanto programa de extensão, já que obteve a nota máxima no Edital ProExt 2014 do Ministério da Educação e, em 2018, foi avaliado como o melhor programa de extensão da UDESC. Com o desenvolvimento continuado deste núcleo e suas ações vinculadas, tem-se consolidado na UDESC uma comunidade de prática e treinamento enxadrísticos junto a um ambiente de pesquisa e estudos interdisciplinares, em que o jogo de xadrez é o elemento integrador.
O XADREZ COMO FERRAMENTA DE INTERAÇÃO SOCIAL EM ALUNOS PARTICIPANTES DO SERVIÇO DE CONVIVÊNCIA E FORTALECIMENTO DE VÍNCULOS
Authors: Brasilino Emerson Nunes , Brusamolin Valério
Published: May 2020

O objetivo desse artigo é estudar os atores que configuram a rede de desenvolvimento da socialização no âmbito do projeto SCFV- Serviço de Convivência e Fortalecimento de Vínculos, utilizando o xadrez como ferramenta tecnológica para a socialização dos alunos do SCFV com base na Teoria de Bruno Latour . A rede é composta por determinados atores, dentre eles destaca-se o xadrez aliado ao Sociodrama, ao projeto SCFV, ao professor/oficineiro, interação social. Com base na óptica de cada ator as conexões e inter- relações são observadas mediante a configuração da rede.
ANÁLISE DA PLATAFORMA SESSA: INSTRUMENTO PARA AVALIAÇÃO DA APRENDIZAGEM EM XADREZ
Authors: Santana Cleiton Marino , Ferreira Ana Julia Candida
Published: May 2020

Resumo: A assimilação das regras é fundamental para nortear a aprendizagem do jogo e, também, para o desenvolvimento das habilidades educacionais constituídas na prática.  Nessa perspectiva de avaliar o nível da aprendizagem dos alunos no xadrez, a plataforma Sessa https://www.plataformasessa.com.br/ apresenta-se como uma ferramenta avaliativa. Este estudo tem como objetivo analisar a proposta e funcionalidade da Plataforma. Essa pesquisa caracteriza-se como uma pesquisa aplicada e exploratória, e tem como objetivo gerar conhecimento para aplicação prática para a solução de problema específico. Observou-se que a plataforma Sessa é capaz de avaliar quantitativamente o nível de aprendizagem sobre as regras do xadrez, os resultados dos testes pode ser classificada por níveis, essa qualificação auxilia o entendimento dos alunos sobre o seu nível. Quando aos testes, verificou-se que o básico apresenta resultados mais rápidos e objetivos enquanto o teste completo resultados mais detalhados. A comparação do pré-teste com o pós-testes ajuda os professores a melhorar suas práticas pedagógicas, pois verificaram as habilidades que ainda não foram aprendidas pelos alunos. A plataforma apresenta um grande potencial de avaliação da aprendizagem das regras de xadrez e possibilita ainda reflexão sobre o processo de ensino-aprendizagem dos professores, ela ainda servirá como um banco de dados para estudos posteriores sobre a aprendizagem.
A composite of clay, cement, and wood as natural support material for the immobilization of commercial titania (P25, P90, PC500, C-TiO2) towards photocatalytic phenol degradation
Authors: Morjène L. , Tasbihi M. , Schwarze M. , Schomäcker R. , Aloulou F. , Seffen M.
Published: May 2020

Different types of commercial titania (P25, P90, PC500, and C-TiO2) were immobilized as single or mixed photocatalyst onto the surface of a natural support material made of cement, clay, and wood fibers. The successful immobilization was studied by different techniques showing a composite material with the mechanical properties of the support material and the photocatalytic behavior of the immobilized titania. The supported photocatalyst showed high mechanical stability and was applied to the photocatalytic degradation of phenol as a model pollutant under UV light irradiation. As the most active photocatalytic material, a mixture PC500 and P90 (comp-PC500/P90) was identified with an apparent pseudo first-order kinetic rate constant (kapp) of 0.010 min−1 at a degradation efficiency of 100%. The catalyst was used several times and showed minor loss in activity during four runs due to degradation intermediates adsorbed to the surface, shown by a color change from white to yellow.
Effects of Chlorine Dioxide on Oral Hygiene - A Systematic Review and Meta-analysis
Authors: Kerémi Beáta , Márta Katalin , Farkas Kornélia , Czumbel László M. , Tóth Barbara , Szakács Zsolt , Csupor Dezső , Czimmer József , Rumbus Zoltán , Révész Péter , Németh Adrienn , Gerber Gábor , Hegyi Péter , Varga Gábor
Published: May 2020

Background:

Effective and selective oral rinses are required in the daily medical and dental practice.
Currently mouthwashes used have substantial side effects.

Objectives:

Our aim was to evaluate the efficacy of chlorine dioxide-containing mouthwashes in comparison with
other previously established mouth rinses in healthy adults using oral hygiene indices.

Methods:

This work was registered in PROSPERO (CRD42018099059) and carried out using multiple databases
and reported according to the PRISMA statement. The search terms used were “chlorine dioxide” AND “oral”,
and only randomised controlled trials (RCTs) were included. The primary outcome was the alteration of the
plaque index (PI), while the secondary outcomes were the gingival index (GI) and bacterial counts. For the risk of
bias assessment, the Cochrane Risk of Bias Tool was used. Statistical analysis for data heterogeneity was performed
by Q-value and I2-tests.

Results:

364 articles were found in the databases. After the selection process, only five RCTs were eligible for
meta-analysis. Data heterogeneity was low. There were no statistical differences in effectiveness between chlorine
dioxide and other effective mouth rinses in PI (0.720±0.119 vs 0.745±0.131; 95%; confidence intervals (CIs):
0.487-0.952 vs 0.489-1.001, respectively) and GI (0.712±0.130 vs 0.745±0.131; 95% CIs: 0.457–0.967 vs 0.489–
1.001, respectively) and also in bacterial counts.

Conclusion:

Chlorine dioxide reduces both plaque and gingival indices and bacterial counts in the oral cavity
similar to other routinely used oral rinses, however, the evidence supporting this outcome is very limited. Therefore,
further large scale RCTs are needed to decrease the risk of bias.
Synthesis, Crystal Structure and Thermal Decomposition of a New Energetic Potassium Salt of dihydridobis(3-nitro-1,2,4-triazolyl) Borate
Authors: Guodong Wang , Yucun Liu , Guoqing Liu , Suming Jing , Longyu Liao
Published: May 2020

A new energetic organic potassium salt of dihydridobis (3-nitro-1,2,4-triazolyl) borate was synthesized from 3-nitro-1,2,4-triazole and potassium borohydride at 110 °C, and structurally characterized by elemental analysis, IR spectra, 13C NMR and singlecrystal X-ray diffraction. Results show that the crystal belongs to monoclinic system with space group of p21 / C and cell parameters of a = 10.335 (8) Å, B = 10.812 (8) Å, C = 9.821 (8) Å, α = 90 ˚, β = 106.470 (13), γ = 90 °, z = 4. Its crystal density is 1.755g/cm3. Thermal properties were studied with TG-DTA and DSC. There was only one sharp decomposition peak temperature of 270 °C at the heating rate of 10 °C/ min-1. The activation energies EK = 48.0kJ/mol-1 and EO = 49.8kJ/mol-1 were calculated by the Kissinger method and Ozawa method respectively (CCDC: 1975139).
Exosome-based Tumor Therapy: Opportunities and Challenges
Authors: Li Chunmei , Hou Xiaoming , Zhang Peng , Li Juan , Liu Xiaoguang , Wang Yuping , Guan Quanlin , Zhou Yongning
Published: May 2020

Background:

Exosomes play an important role in transferring information among different cell types, as they transport materials from the cell membrane to the cytoplasm. They are involved not only in normal physiological functions, but also in the occurrence and development of a variety of diseases. Cancer is a major health problem affecting humans. Currently, exosomes are considered novel stars in tumor therapy.

Objective:

To present a review focusing on the role of exosomes in tumorigenesis and development and the possibility of treating tumors with exosome-targeted therapies or using exosomes as carriers.

Methods:

We reviewed literature related to the biological origin and function of exosomes and exosome-tumor relationship.

Results:

Exosomes are closely related to tumor immunity, angiogenesis, pre-metastasis microenvironment, chemoresistance, energy metabolism, etc. Tumor therapy involving the targeting of exosomes involves block the generation, secretion, uptake of exosomes, and elimination of circulating exosomes, and develop antitumor vaccines. Exosome as delivery vehicles can be loaded with chemotherapeutic drugs, therapeutic genes, and other therapeutic drugs to target cells. Prospects and challenges of exosome-based tumor therapy are also discussed.

Conclusion:

Exosomes are involved in multiple processes during tumor development and should be further studied as novel targets for cancer therapy.
Hydralazine-Induced ANCA Associated Vasculitis (AAV) Presenting with Pulmonary-Renal Syndrome (PRS): A Case Report with Literature Review
Authors: Doughem Karim , Battisha Ayman , Sheikh Omar , Konduru Lakshmi , Madoukh Bader , Al-Sadawi Mohammed , Shaikh Shakil
Published: May 2020

:

Hydralazine, an arterial vasodilator, is a widely used medication for the management of
hypertension and heart failure, especially for patients who cannot tolerate the use of ACEIs or
ARBs. It is generally well-tolerated and has a safe profile in pregnancy. However, hydralazine can
induce immune-mediated side effects, such as hydralazine-induced lupus and less commonly hydralazine-
induced ANCA vasculitis. The latter most commonly affects the kidneys with or without
other organ involvement. There are several cases reported in the literature of hydralazine-induced
ANCA associated vasculitis (AAV) that have pulmonary manifestations, also known as hydralazine-
induced pulmonary-renal syndrome (PRS), a condition with a high risk of mortality. We are
reporting a case of Hydralazine-induced ANCA associated glomerulonephritis with severe diffuse
alveolar hemorrhage (DAH). In addition, we will review the current literature and discuss the importance
of prompt diagnosis and early management to decrease mortality and morbidity associated
with this serious condition.
The Role of Direct Oral Anticoagulant in Patients with Acute Coronary Syndrome on Single or Dual Antiplatelet Regime: Review of Opportunities and Challenges
Authors: Elnour Asim A. , Komócsi András , Kupó Péter , El Khidir Israa Y. , Zachariah Seeba , Sam Kishore G. , Asim Sahar , Sadeq Adel
Published: May 2020

Background:

Despite the developments of single or dual antiplatelet therapy consisting
of aspirin and/or clopidogrel, prasugrel or ticagrelor, post-acute coronary syndrome a room for potential
improvement towards optimal prevention persist. The addition of a direct oral anticoagulant
to the antiplatelet treatment of patients with the acute coronary syndrome is clinically practiced in
cases where anticoagulation is indicated by high thromboembolic risk.

Objective:

The main objective of this review was to explore the role of supplementation with a direct
oral anticoagulant to antiplatelet (aspirin or P2Y12 inhibitor) in patients with the acute coronary
syndrome.

Methods:

We have searched the Medline for studies involving direct oral anticoagulant use in acute
coronary syndrome. We have reviewed specific relevant 9 meta-analyses between the years 2012 to
2019.

Results:

Our review of nine meta-analyses has revealed that the addition of direct oral anticoagulant
to antiplatelet therapy compared with antiplatelet alone was beneficial about the composite endpoints
of major ischemic events in patients with the acute coronary syndrome. Furthermore, the
combined regimen of single antiplatelet plus direct oral anticoagulant is as effective as the triple
regimen of dual antiplatelet plus direct oral anticoagulant and results in less bleeding.

Conclusion:

Cardiologists should balance the efficacy with a higher risk of bleeding with more
intensified DOAC therapy. Better risk characterization and timely adaptation of the regime to the
patient's need should be tested. Recurrent ischemic events and bleeding event risk scoring should
guide individualized treatment.
Chronic Suppurative Otitis Media: A Case Report
Authors: Yazdi M.M. Karimi , Ghalavand Zohreh , Yazdi Alireza K. , Kodori Mansoor , Taheri Marzieh , Tabriz Mahboobeh S. , Eslami Gita
Published: May 2020

Background Context:

Chronic Suppurative Otitis Media (CSOM) is a common cause
of hearing impairment and disability. CSOM caused by Pseudomonas aeruginosa is usually
treated with topical ciprofloxacin and resistance to ciprofloxacin in CSOM isolates has rarely been
reported.

Case Presentation:

A 24-year-old male patient with CSOM due to p. aeruginosa was reported.
CSOM was prolonged for ten years and physician prescribed topical ciprofloxacin drops, pus suctioning
and ear pH alteration. The treatment wasn’t effective and the patient came back to the
clinic with relapse of suppurative otitis media. P. aeruginosa was isolated as the cause of CSOM
and the isolate was resistant to ciprofloxacin, aztreonam, imipenem, gentamicin, doripenem, cefepime,
levofloxacin, amikacin and susceptible to colistin and ceftazidime. There were two mutations
in gyrA and eight mutations were observed in nfxB genes. Finally, tympanomastoidectomy
was done.

Conclusion:

Usually topical antibiotics, especially ciprofloxacin, is effective against ear infections
but our case was different and the P. aeruginosa isolated from CSOM was resistant to most
of the antibiotics. One reason for CSOM recurrence might be surgery failure. The routine and primary
treatment for CSOM did not seem sufficient and tympanomastoidectomy is suggested to be
the best treatment approach for these patients.
The Combination of rTMS and Pharmacotherapy on In Vitro Models: A Mini-Review
Authors: Pourzitaki Chryssa , Dardalas Ioannis , Poutoglidou Frideriki , Kouvelas Dimitrios , Kimiskidis Vasilios K.
Published: May 2020

Background:

Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive brain stimulation technique that is being actively explored as a potential therapeutic modality in various neuropsychiatric disorders, such as depression, neuropathic pain, epilepsy, multiple sclerosis, and neurodegenerative disorders, including the Parkinson’s and Alzheimer’s disease. The Food and Drug Administration (FDA) approved rTMS for the treatment of major depression, migraine-associated headaches, and Obsessive Compulsive Disorder (OCD). The fact that a significant proportion of patients suffering from these disorders fail to respond to current pharmacological interventions indicates the need for alternative therapies like rTMS.

Objective:

The objective was to find and summarize all studies combining the use of rTMS and pharmacological interference in vitro, in order to facilitate future studies.

Methods:

The results of studies combining the use of rTMS with pharmacological interference in vitro were focused on. The PubMed database was searched using the terms “rTMS”, “repetitive”, “transcranial”, “magnetic”, “stimulation”, “in vitro”, “in vivo”, “cell cultures” untilMarch 2019 and 7 eligible studies were found.

Results:

Overall results show a synergistic effect of rTMS and pharmacotherapy in vitro with additive effectiveness, better prognosis, and superior potential management.

Conclusion:

The limited amount of knowledge denotes the need for additional in vitro studies on the combination of rTMS and pharmacotherapy, which could be extended to in vivo studies and ultimately help design clinical trials so as to improve the therapeutic management of patients with a wide array of neuropsychiatric disorders.
Promising Use of the New Biologics in the Management of Drug-Induced Hypersensitivity Reactions: Preliminary Approaches
Authors: Calogiuri Gianfranco , Brockow Knut , Nettis Eustachio , Macchia Luigi , Foti Caterina , Vacca Angelo
Published: May 2020

Biologics are an innovative class of drugs that can selectively influence immunological
responses at a cellular level. Although their use is usually restricted to some specific diseases, such as
autoimmune pathologies and tumors, their “off-label” administration has increased widely in the last
years. Drug treatment may induce hypersensitivity reactions which currently lack any gold standard
therapy but maybe a future field of application for biologics. Agents like anti-IgE (Omalizumab) and
Tumor Necrosis Factor-α inhibitors might be used in immediate-type and cell-mediated hypersensitivity
caused by medications, respectively, and the first trials in that direction are being reported in the
literature. In fact, the refined immunological mechanisms involved in the pathogenesis of drug hypersensitivity
might respond successfully to this new class of drugs.
Een sensitieve snelle benoemtest voor woordvindproblemen bij patiënten met een laaggradig glioom
Authors: Ras Priscilla , Satoer Djaina , Rutten Geert-Jan , Vincent Arnaud , Visch-Brink Evy
Published: May 2020

Patiënten met een laaggradig glioom (langzaam groeiende hersentumor) rapporteren vaak woordvindproblemen, terwijl deze met de huidig gebruikte benoemtests in de praktijk vaak niet geobjectiveerd worden. In deze studie worden de resultaten van een sensitieve snelle benoemtest (SBT) voor objecten besproken, toegepast bij deze patiëntengroep.

Via deze nieuwe test werden reactietijden verzameld van 18 patiënten met een vermeend laaggradig glioom en van 20 gezonde participanten. Om uit te sluiten dat bij glioompatiënten tragere reactietijden worden gevonden als gevolg van algehele cognitieve traagheid, zijn de resultaten van een test voor cognitieve snelheid (Trail Making Test-A, TMT-A) meegenomen in het onderzoek. De resultaten op de SBT zijn vergeleken met de resultaten op de klinisch veel gehanteerde Boston Naming Test (BNT) om zo de toegevoegde waarde van de SBT te kunnen evalueren. Tevens is het effect van woordfrequentie en Age of Acquisition (AoA) op de benoemtijden onderzocht. Glioompatiënten waren significant langzamer in het benoemen van de objecten dan de gezonde participanten. De tragere reactietijdenwerden niet verklaard door een algeheel tragere verwerkingssnelheid. Ook de BNT-scores konden de lagere reactietijden op de SBT niet verklaren. Een kwalitatieve vergelijking tussen de resultaten van de BNT en de SBT duidde op een hogere sensitiviteit van de SBT voor woordvindproblemen. In de groep gezonde participanten wordt een effect gevonden van woordfrequentie en AoA op de benoemsnelheden, in de patiëntengroep is echter geen effect van deze variabelen waar te nemen.

De resultaten laten een duidelijk verschil in benoemsnelheid zien tussen laaggradige glioompatiënten en gezonde participanten, terwijl patiënten zelden een afwijkende score behaalden op de BNT. Het lijkt zinvol om de SBT te gebruiken in de klinische praktijk, waarbij reactietijden als een belangrijk component meegenomen worden voor het diagnosticeren van woordvindproblemen bij glioompatiënten.
Knightly heroes in the later Middle Ages
Authors: Van Steensel Arie
Published: May 2020

Review of Elizabeth Morrison, ed., A knight for the ages. Jacques de Lalaing and the art of chivalry (Los Angeles: The J. Paul Getty Museum, 2018, 192 p., ill., index); and Gero Schreier, Ritterhelden. Rittertum, Autonomie und Fürstendienst in niederadligen Lebenszeugnissen des 14. bis 16. Jahrhunderts, Mittelalter-Forschungen, LVIII (Ostfildern: Jan Thorbecke Verlag, 2019, 393 p., index).
When future teachers meet real learners through telecollaboration: an experiential approach to learn how to teach languages online
Authors: Cappellini Marco , Hsu Yu-Yin
Published: May 2020

The integration of technology in language teaching has been one important topic in language education and teacher training. Teacher education has been one of the aims of telecollaboration since the beginning of the 2000’s. While the first pioneers worked with small groups of students (Develotte, Mangenot, & Zourou, 2005; MüllerHartmann, 2006), more recent projects are widening the application of telecollaboration for teacher education (Baroni et al., 2019). In the present article we present an adaptation of the model of Le Français en (Première) Ligne (hereafter F1L) proposed by Develotte et al. (2005) in two telecollaborative projects aiming at developing trainees’ techno-semiopedagogical competences.
Emanuel John: Die Negativität des Sittlichen
Authors: Gebrecht Raphael
Published: May 2020

Rezension von Emanuel John: Die Negativität des Sittlichen. Zur Überwindung ethischen Leides. Freiburg/München: Karl Albers 2019.
Data Analysis of COVID-19 THE GREAT EPIDEMIC OF THE YEAR 2020 (Preprint)
Authors: Singla Sonia
Published: May 2020

UNSTRUCTURED

What is COVID-19, and how to deal with COVID-19 during pandemic. Does it is the result of harming nature? Mostly the disease was spread from Wuhan, China and is found bat to be the cause of spreading to other animals which has infected human. Italy, Spain and almost all the world is facing the consequence of COVID-19. In India where the prevalence rate of disease is 1.9% and 2.5% incidence rate, most of the cases are being found in Kerala and Maharashtra with updated data more than 200. Now the question arises is wet and cold climate making the virus spread and can the virus be killed in high temperature and high humidity? After Italy, China more death cases have been found in Spain. Data Science plays a major role by using machine learning to solve various problems and can be used to solve various problems associated with COVID-19. For example, prediction of how many peoples in groups will get effected, which location or area is likely to be get effected, screening of patients, using chat boots for concluding how many peoples have got the symptoms and are likely to be effected and so on.
In this paper we have tried to show which areas are more likely to be affected, how lockdown have helped in reduction of death and what in future we can do to not face such situation again in life.
Evaluating Apple Inc Mobility Trend Data Related to the COVID-19 Outbreak in Japan: Statistical Analysis (Preprint)
Authors: Kurita Junko , Sugishita Yoshiyuki , Sugawara Tamie , Ohkusa Yasushi
Published: May 2020

BACKGROUND

In Japan, as a countermeasure against the COVID-19 outbreak, both the national and local governments issued voluntary restrictions against going out from residences at the end of March 2020 in preference to the lockdowns instituted in European and North American countries. The effect of such measures can be studied with mobility data, such as data which is generated by counting the number of requests made to Apple Maps for directions in select countries/regions, sub-regions, and cities.

OBJECTIVE

We investigate the associations of mobility data provided by Apple Inc and an estimate an an effective reproduction number R(t).

METHODS

We regressed R(t) on a polynomial function of daily Apple data, estimated using the whole period, and analyzed subperiods delimited by March 10, 2020.

RESULTS

In the estimation results, R(t) was 1.72 when voluntary restrictions against going out ceased and mobility reverted to a normal level. However, the critical level of reducing R(t) to <1 was obtained at 89.3% of normal mobility.

CONCLUSIONS

We demonstrated that Apple mobility data are useful for short-term prediction of R(t). The results indicate that the number of trips should decrease by 10% until herd immunity is achieved and that higher voluntary restrictions against going out might not be necessary for avoiding a re-emergence of the outbreak.
Canada’s Decentralized “Human-Driven” Approach During the Early COVID-19 Pandemic (Preprint)
Authors: Hansen Gregory , Cyr Amelie
Published: May 2020

UNSTRUCTURED

A country’s early response to a pandemic is critical for controlling the disease outbreak. During the COVID-19 pandemic, a number of southeast Asian countries adopted centralized, coordinated, rapid, and comprehensive approaches that involved smart technology (the “techno-driven” approach). In comparison, Canada’s approach appeared to be decentralized, uncoordinated, and slow, and it focused on educating citizens and enhancing social and human capital (the “human-driven” approach). We propose that in future pandemics, early and coordinated “techno-driven” approaches should receive more careful consideration to curtail outbreaks; however, these approaches must be balanced with protecting individuals’ freedoms.
Effects of Stem Cutting Time and Height on Yield Components and Yield of Rice Ratun System (Oryza sativa L.)
Authors: Nuzul Vicky Silvia
Published: May 2020

Ratun is the ability of the rice plant to regenerate new tillers after harvest, so it can be increased rice productivity. The aim of this research was to compare the yield components and yield between rice ratun with the parent rice, to analyze influence of stem cutting time and height on yield components and yield of rice ratun system and also to determine optimum cutting time and height for the yield components and yield of rice ratun. This research was heald in Pusat Inovasi Agroteknologi (PIAT) of  Gadjah Mada University, Kalitirto, Berbah, Sleman, Yogyakarta on March to June 2017.  The experiment used split-plot design with cutting time as the main plot and cutting height as sub plot with 3 blocks as replication. The cutting time consisted of 3 levels i.e. at harvest time, 7 days after harvest time, and 14 days after harvest time.  Meanwhile, cutting height consisted of 4 levels i.e. 3 cm, 13 cm, 23 cm, and 33 cm above the ground.The research showed that the yield components and yield of rice ratun lower than the parent rice. Cutting time at harvest time, 7, 14 days after harvest time with the cutting height close to the ground increase yield component and yield of rice ratun but delay the generative phase. The highest yield components and yield of rice ratun achieved at harvest time cutting time with cutting height 3 cm above the ground.
Karakter Morfologi Akar dan Hasil Padi Ratun (Oryza sativa L.) pada Perbedaan Waktu dan Tinggi Pemotongan Tunggul Sisa Panen
Authors: Pratama Ananta Bayu , Indradewa Didik , Ambarwati Erlina
Published: May 2020

Penelitian ini bertujuan untuk menentukan waktu dan tinggi pemotongan tunggul sisa panen yang optimal untuk mendukung pertumbuhan akar sehingga diperoleh daya hasil padi ratun maksimal. Percobaan lapangan disusun dalam Rancangan Acak Lengkap split plot 2 faktor dan 3 blok sebagai ulangan.  Percobaan lapangan disusun dalam Rancangan Acak Kelompok Lengkap split plot 2 faktor dan 3 blok sebagai ulangan.  Petak utama berupa waktu pemotongan tunggul, terdiri dari 3 taraf yaitu: saat panen (0 HSP), 7 hari setelah panen (7 HSP) dan 14 hari setelah panen (14 HSP). Anak petak berupa tinggi pemotongan tunggul, terdiri dari 4 taraf yaitu: 4 cm, 14 cm, 24 cm dan 34 cm. Variabel yang diamati berupa variabel morfologi akar dan hasil padi ratun. Data yang diperoleh dianalisis varians (ANOVA) dengan taraf kepercayaan 95%, dilanjutkan dengan uji polinomial orthogonal. Hubungan antar variabel pengamatan ditentukan dengan analisis korelasi. Hasil penelitian memberi informasi bahwa waktu pemotongan tunggul sisa panen hanya berpengaruh nyata terhadap diameter akar dengan waktu pemotongan terbaik 10 HSP yang menghasilkan diameter terbesar 0,89 mm, ketika dilakukan pemotongan tunggul setinggi 4 cm di atas permukaan tanah, namun tidak berpengaruh nyata terhadap sifat perakaran lainnya. Fase vegetatif yang paling lama (44 hari) dan  produktivitas gabah yang paling tinggi (3,39 – 3,54 ton/ha) diperoleh bila tunggul dipotong setinggi 4 cm di atas permukaan tanah, namun perbedaan waktu pemotongan tunggul tidak berpengaruh nyata terhadap kedua variabel tersebut.
Pengaruh Lama Penyinaran Tambahan Krisan (Dendranthema sp.) Varietas Bakardi Putih dan Lolipop Ungu terhadap Pertumbuhan dan Hasil
Authors: Puspitasari Sylvatera Ayu , Indradewa Didik
Published: May 2020

Krisan merupakan tanaman hari pendek. Jika tanaman ini mendapatkan panjang malam lebih dari 12 jam dalam sehari maka fase vegetatif (pertambahan tinggi) tidak berlangsung lama. Untuk mempertahankan fase vegetatif tanaman krisan maka perlu dilakukan penambahan lama penyinaran di malam hari. Penelitian ini bertujuan untuk mempelajari pengaruh lama penyinaran terhadap pertumbuhan, hasil dan kualitas varietas krisan yang berbeda serta mempelajari lama penyinaran tambahan optimal untuk menyerempakkan umur panen varietas krisan yang berbeda. Penelitian ini akan dilaksanakan pada bulan Agustus 2017 hingga Maret 2018 bertempat di lahan pertanaman krisan dan rumah plastik milik Asosiasi Tanaman Hias Bunga dan Daun Potong (ASTHABUNDA) Jalan Kaliurang km 21, Panggeran, Hargoninangun, Pakem, Sleman, DIY. Penelitian menggunakan Rancangan Faktorial 2 x 5, tata letak Rancangan Acak Kelompok Lengkap dengan tiga blok sebagai ulangan. Faktor 1 adalah lama penyinaran tambahan dengan 5 aras yaitu 0 hari (tanpa penyinaran), 10 hari, 20 hari, 30 hari dan 40 hari. Faktor 2 adalah varietas yaitu Bakardi Putih dan Lolipop Ungu. Kombinasi perlakuan berjumlah 10 perlakuan dengan masing masing kombinasi 3 sampel tanaman dengan 3 ulangan. Hasil penelitian menunjukkan penyinaran tambahan 20 hari pada varietas Bakardi Putih dan 30 hari Lolipop Ungu menghasilkan bunga krisan yang telah memenuhi grade A SNI. Peningkatan lama penyinaran tambahan sampai dengan 40 ari dapat meningkatkan pertumbuhan, hasil dan kualitas varietas Bakardi Putih lebih baik dibandingkan varietas Lolipop Ungu. Penyinaran tambahan 20 hari pada varietas Bakardi Putih dan 30 hari varietas Lolipop Ungu belum dapat menyerempakkan umur panen kedua varietas. Pada penyinaran 20 hari, umur panen varietas Bakardi Putih 86 hari dan 30 hari varietas Lolipop Ungu 106 hari.
Hubungan Sifat Perakaran dan Ketahanan Kekeringan Lima Kultivar Kedelai (Glycine max L.)
Authors: Purbowahyuani Roosanna , Kastono Dody , Indradewa Didik
Published: May 2020

Cekaman kekeringan merupakan salah satu faktor pembatas dalam budidaya tanaman kedelai di Indonesia. Salah satu upaya menanggulangi penurunan hasil yang disebabkan oleh kekeringan adalah dengan menggunakan kultivar kedelai yang tahan terhadap cekaman kekeringan. Penelitian dilakukan di rumah plastik di Kebun Tridharma Banguntapan, sub Laboratorium Ilmu Tanaman dan Laboratorium Ekologi Tanaman, Fakultas Pertanian, Universitas Gadjah Mada, Yogyakarta, dari bulan April-Agustus 2018. Penelitian ini bertujuan untuk mempelajari hubungan antara sifat perakaran dan toleransi cekaman kekeringan lima kultivar kedelai. Rancangan percobaan yang digunakan adalah petak terbagi (split plot) dengan tiga ulangan. Petak utama adalah pemberian air yang terdiri dari dua aras yaitu disiram sehari sekali dan disiram tujuh hari sekali. Anak petak berupa kultivar kedelai terdiri dari kultivar Anjasmoro, Burangrang, Demas 1, Dering 1, dan Devon 1. Data yang diperoleh kemudian dianalisis dengan analisis varian (ANOVA). Apabila terdapat beda nyata antar perlakuan, dilakukan uji lanjut Beda Nyata Jujur (BNJ) Tukey dengan taraf kepercayaan 95%. Hasil penelitian menunjukkan bahwa, kultivar kedelai yang paling tahan terhadap kekeringan adalah Demas 1. Kultivar kedelai yang tahan kekeringan memiliki permukaan akar yang lebih luas dibanding kultivar kedelai yang rentan kekeringan.
Serapan Hara N, P, K dan Hasil Biji Kedelai (Glycine max L. Merrill) pada Pemberian Bokashi Pelepah Pisang pada Tanah Pasir Pantai
Authors: Faozi Khavid , Yudono Prapto , Indradewa Didik , Ma'as Azwar
Published: May 2020

The ability of several soybean varieties to absorb nutrient nitrogen, phosphorus and potassium (NPK) may be different in the new growing environment in coastal sands which are treated with bokashi made from banana stem. The aim of this study was to determine the NPK nutrient uptake and the responses of several soybean varieties to the level of banana stem bokashi application in coastal sand fields and to determine the optimum dose based on the yield of soybean seeds. The research was a field experiment conducted for 4 months from January until April 2017. Pot experiments in the field have been done in Samas coastal sands, Srigading Village, Sanden Sub-district, Bantul Regency, Special Region of Yogyakarta. The factorial experiment (4x12) was repeated 3 times, arranged in a complete randomized block design (RCBD). The first factor was dose banana stem bokashi including 0, 20, 40, and 60 t.ha-1; was tested on 12 soybean cultivars namely Anjasmoro, Argomulyo, Burangrang, Demas 1, Dena 1, Devon 1, Gamasugen 1, Gema, Gepak Ijo, Grobogan, Kaba, and Slamet. The observational data were analyzed by the variant analysis of the error rate of 5% and if significantly different was followed by DMRT 5% error level. The results showed that bokashi made from the banana stem can be used as a soil enhancer for coastal sandy soil, as well as providing nutrients for the growth of soybean plants. Nutrient uptake of N, P, K, plant dry weight, and seed yields of Anjasmoro varieties, Argomulyo, Demas 1, Devon 1, Gepak Ijo, Kaba and Slamet increased with the application of banana stem bokashi at doses of  20 and 40 t.ha-1, and decreases at bokashi doses reaching 60 t.ha-1. The optimum dose of bokashi made from banana stem doses equals 35.80 t.ha-1 with a maximum seed yield of 22.24 g.pot-1.
Tanggapan Teki terhadap Cekaman Kekeringan pada Berbagai Jenis Tanah
Authors: Paiman Paiman
Published: May 2020

Teki (Cyperus rotundus) merupakan salah satu gulma dominan yang dapat tumbuh pada berbagai lahan pertanian dan berbagai jenis tanah pada kondisi air yang terbatas. Penelitian ini bertujuan untuk mengetahui pertumbuhan dan tanggapan teki terhadap cekaman kekeringan pada berbagai jenis tanah. Penelitian ini menggunakan percobaan pot yang disusun dalam rancangan tersarang dan diulang tiga kali. Faktor pertama yaitu jenis tanah yang terdiri atas 4 jenis yaitu tanah pasir pantai, alluvial, vulkanik dan grumusol. Faktor kedua yaitu cekaman kekeringan yang terdiri atas empat aras yaitu 25%, 50%, 75% dan 100% kapasitas lapang. Pengamatan meliputi tinggi gulma, panjang akar, jumlah umbi, luas daun, berat daun khas, rasio tajuk akar, kandungan prolin dan bobot kering gulma. Data hasil pengamatan dianalisis dengan analisis varian pada jenjang nyata 5%.  Perbedaan antara perlakuan dianalisis dengan uji jarak berganda Duncan pada jenjang nyata 5%. Hasil penelitian menunjukkan pertumbuhan teki pada tanah grumusol memiliki tinggi lebih tinggi, akar lebih panjang, berat kering gulma lebih berat. Namun, teki yang tumbuh pada tanah pasir pantai memiliki jumlah umbi lebih banyak, daun lebih luas, rasio tajuk akar dan kandungan prolin lebih tinggi. Daun teki terluas ditemukan pada teki yang tumbuh pada tanah pasir pantai dan grumusol. Daun tertebal ditemukan pada tanah vulkanik. Teki yang tumbuh pada tanah dengan kadar air 25% kapasitas lapang mennujukkan tinggi dan panjang akar lebih pendek, daun lebih sempit, jumlah umbi lebih sedikit, bobot kering lebih rendah dan kandungan prolin lebih tinggi. Terjadi interaksi nyata antara jenis tanah dan cekaman kekeringan pada parameter kandungan prolin daun.
A paixão do Entusiasmo, em Diana Luz Pessoa de Barros. Elucubrações semio-patafísicas
Authors: Beividas Waldir
Published: May 2020

Este texto de homenagem à nossa sempre mestre e guia teórico, Diana Luz Pessoa de Barros, pretende indicar breves pistas de estudos semióticos sobre a paixão do entusiasmo, tomando por inspiração a fina análise modal que Greimas fizera sobre a paixão da cólera, nos anos 1980, mas, desta feita, advertida quanto aos movimentos tensivos da semiótica de Zilberberg. A ideia foi mostrar que o estilo de pesquisa e de atitude teórico-acadêmica de Diana está balizado numa verdadeira paixão de entusiasmo, intenso, perante as ações de si própria e perante as ações do outro. Num segundo movimento do texto, a homenagem utiliza expedientes da ciência patafísica de Alfred Jarry para tecer certas elucubrações sobre onomástica, aplicada às quatro grandezas que definem o nome da homenageada: Diana, Luz, Pessoa, Barros.
ФОТОНИКА – НОВЫЙ ДРАЙВЕР GaAs
Authors: Кульчицкий Н.А. , Наумов А.В. , Старцев В.В.
Published: May 2020

Показано, что размещение дифракционной микроструктуры на плоской поверхности одной из рефракционных линз высокоапертурного триплета позволяет одновременно выполнить условия коррекции как хроматических, так и монохроматических аберраций и получить объективы, рассчитанные на средний и двойной инфракрасные диапазоны, имеющие достаточно высокие оптические характеристики.
ФАЗОВЫЕ ДИФРАКЦИОННЫЕ ОПТИЧЕСКИЕ ЭЛЕМЕНТЫ С ПОВЫШЕННОЙ ЭФФЕКТИВНОСТЬЮ ДЛЯ НАНОСКОПИИ
Authors: Прокопова Д.В. , Котова С.П.
Published: May 2020

Представлены результаты исследований по созданию фазовых дифракционных элементов, формирующих световые поля, в распределении интенсивности которых наблюдаются два главных максимума, вращающиеся при фокусировке и распространении. Их получение основано на оптике спиральных пучков света. Такие оптические элементы можно использовать для модификации функции рассеяния точки оптического флуоресцентного микроскопа с целью создания наноскопа – устройства, позволяющего проводить трехмерную локализацию излучающих объектов с нанометровой точностью.