bluuebunny/crossref_metadata_2025 huggingface dataset:
Protective Effect of Pyridoxine on Lead Nitrate Induced Histomorphological Changes in Rat Liver
Authors: Abbasi Sumaira , Khan Huma Musarrat , Khan Muhammad Yunus
Published: October 2022

Objective: To study the effects of Pyridoxine on lead nitrate generated histological and morphological changesin rat liver.Study Design: It was an experimental study.Place and Duration of Study: The study was carried out at Anatomy Department of College of Physicians andrd st Surgeons, Islamabad, Pakistan from 03rd September, 2019 to 31st December, 2020.Materials and Methods: In this study 90 male rats were used and divided into three groups. Control group Awas kept on normal diet. Experimental group B1 was given lead nitrate and B2 was given lead nitrate andpyridoxine by oral gavage for a period of 2 weeks. All rats were sacrificed after 2 weeks. Results of quantitativevariables such as inflammatory and Kupffer cells were expressed in mean ± S.D. To detect significant differenceamong the groups, ANOVA accompanied by Post Hoc Tukey test was applied and qualitative data such as central vein congestion, steatosis, and necrosis were expressed in percentages and Chi Square test.Results: Exposure to pyridoxine reduces the degenerative changes caused by lead nitrate such as increase inthe number of Kupffer and inflammatory cells. Central vein congestion, steatosis and necrotic foci were alsoreduced with a significant p-value.Conclusion: An ameliorative effect of pyridoxine on the degenerative changes in the liver induced by leadnitrate was proven through a decrease in the number of kupffer and inflammatory cells. Central veincongestion, steatosis and necrotic foci were also reduced significantly.

How to cite this: Abbasi S, Khan HM, Khan MY. Protective Effect of Pyridoxine on Lead Nitrate Induced Histomorphological Changes in Rat Liver. Life and Science. 2022; 3(4): 163-167. doi: http://doi.org/10.37185/LnS.1.1.269
Choreiform-Ballistic Movements Due to Endocrine Deficiencies
Authors: Haroon Maryam
Published: October 2022

Choreiform-ballistic movements are often associated with lesions in the basal ganglia and subthalamicnucleus. For a patient with dancing movements, hyperglycemia might be an initial presentation. We herebypresent a case of a young 19 years old girl already on insulin and presented with the sub-acute onset ofabnormal movements. The purpose of this case report was to elaborate the possibility of choreiformmovements as a rare presentation of endocrine deficiencies like type I diabetes in association withpseudohypoparathyroidism as well as the role of insulin, calcium, and vitamin D analogues in reducing thefrequency and severity of these movements. Literature review showed a similar presentation with hyperosmolarnon-ketotic coma / hyper-osmolar hyperglycemic state (HONK/HHS) secondary to type 2 diabetesmellitus in middle and old-aged patients but not reported so far in young patients having type I diabetesmellitus with other underlying endocrine abnormalities.How to cite this: Haroon M. Choreiform-Ballistic Movements Due to Endocrine Deficiencies. Life and Science. 2022; 3(4): 203-205. doi: http://doi.org/10.37185/LnS.1.1.274
Acupuncture Does Work and is Not Just Based on a Mere Placebo Effect!
Authors: Liem Andrew KSE
Published: October 2022

Acupuncture (a treatment method through stimulation with needles of specific treatment points aimed at energy pathways, the meridians, to bring the body back into balance) has been part of traditional Chinese medicine (TCM) for over 2000 years now. Modern medical acupuncturists trained in the West understand and use acupuncture in addition to or even as an alternative to modern therapeutic concepts. In addition to the mother country of China, acupuncture is used by millions of patients in the US and Germany, and for certain indications simply reimbursed by health insurers. So far, no real physiological mechanism explains its action, although an analgesic effect has been proven. In the current age of evidence-based medicine, this leads to controversial discussions that are usually very emotional and where physician-acupuncturists are often portrayed as quacks. Most studies on acupuncture come from China and are mostly published in Chinese and all too often of poor quality. However, there are also good randomized controlled trials (RCTs) on acupuncture that show significant effects at least in pain and postoperative nausea and vomiting (PONV).
Vulnerability to SARS-CoV-2 infection and disease: ripping the curl after the storm
Authors: Barreiro Pablo , San Román Jesús
Published: October 2022

SARS-CoV-2 infection now seems to have entered the announced endemic phase. The population’s immunity is increasingly more robust, thanks to successive vaccination and booster campaigns, and the almost inevitable exposure and re-exposure to the virus itself, which has truly served as a natural immunizing mechanism. On the other hand, the genetic drift of the virus is leading it to become another catarrhal agent, as are the other endemic human coronaviruses. However, it should not be lost sight of that there are still segments of the population with susceptibility to severe COVID, who will be candidates to continue receiving vaccine boosters or antiviral drugs in the initial stages of infection.
Norovirus infection as a model of chronic or recurrent infection in common variable immunodeficiency
Authors: Moral Moral Pedro , Cabañero-Navalon Dafne , Garcia-Bustos Victor , Núñez Beltrán María , Salavert Lletí Miguel
Published: October 2022

Common variable immunodeficiency (CVID) is the most frequent symptomatic primary immunodeficiency (PID) in general population. PID are genetic diseases that share a dysfunction in the immune system entailing a greater risk of both chronic and recurrent infections. These patients can also develop chronic gastrointestinal infections caused by norovirus with persistent viral dissemination, which can be detected months after primoinfection. Additionally, a proportion of CVID patients show a typical severe enteropathy presenting with recurrent diarrhoea, intestinal malabsorption, inflammatory lesions, and villous atrophy. Some studies have related this enteropathy with chronic intestinal infection caused by norovirus.
New definitions of susceptibility categories EUCAST 2019: clinic application
Authors: Nabal Díaz Sandra G. , Algara Robles Olga , García-Lechuz Moya Juan M.
Published: October 2022

In January 2019, the European Committee for the Study of Antimicrobial Susceptibility (EUCAST) introduced some changes in the definitions of clinical categories for antibiotic susceptibility. The objective of these changes was to improve the credibility of category “I”, optimizing and lengthening the survival and use of available antibiotics in the face of increasing antimicrobial resistance. This article aims to describe and explain these changes in the EUCAST criteria as well as make a short review about the factors on which the antibiotic susceptibility criteria depend.
Latent tuberculosis infection: approach and therapeutic schemes
Authors: Fortún Jesús , Navas Enrique
Published: October 2022

Tuberculosis continues to be a major public health problem. A priority objective is the implementation of early diagnosis, contact investigation and latent tuberculosis infection (LTBI) testing. World Health Organization (WHO) concludes that there is no gold standard for the diagnosis of LTBI; both the tuberculin test and IGRA (interferon gamma release assays) indirectly identify tuberculosis infection; both tests are considered acceptable but imperfect. WHO recommends that regimens that include rifamycins are equally effective but less toxic and more adherent than long regimens with isoniazid.
Timing in antibiotic therapy: when and how to start, de-escalate and stop antibiotic therapy. Proposals from a stablished antimicrobial stewardship program
Authors: Pasquau-Liaño Juan
Published: October 2022

The current morbimortality of serious infections is unacceptable and there is a need to promote the increase in the efficacy of empirical and targeted antibiotherapy. This could be achieved by initiatives coming from ASP teams aimed at promoting increased efficacy of antibiotic therapy .In the optimization of the antibiotic therapy there are several critical points in which an adequate timing could achieve benefits in the survival of patients with severe infections: prompt initiation of empirical treatment; de-escalation performance, appropriate targeted treatment; and finally, curtail antibiotic duration.
When Existence is Inefficient
Authors: Jackson Allyn
Published: October 2022

How hard is it to solve a problem when a solution is guaranteed to exist? It is to address questions like this that the theoretical computer scientist Christos Papadimitriou invented the complexity class PPAD. Allyn Jackson explores the origins and impact of PPAD, whether Nash equilibrium points are PPAD-complete, and how PPAD differs from the better-known complexity class NP.
THE HOSPITALITY INDUSTRY DEVELOPMENT FACTORS
Authors: Humenyuk Anzhela
Published: October 2022

Purpose. The purpose of the article is to systematize the main factors in the development of hospitality, which exist at the present stage of development.

Methodology of research. In order to implement research tasks, the use of a number of methods that form the basis of research methodology is provided. In particular, the theoretical aspects of systematization of approaches and features are formulated using the method of systematization, which allowed to identify key elements within the research issues. The comparative method required to compare and supplement the statements of the authors who studied these issues was also used.

Findings. The systematization of the main factors of hospitality development, which exist at the present stage of development, is presented. The main scientific approaches that determine the characteristics of the classification of factors of hospitality development are identified, among which are: the approach that involves the structuring of factors in this category, related to the focus on performance (critical impact) and predictability in the future; the approach, which establishes the classification of factors of formation of partnership of hospitality entities between themselves and related market participants (a sign of partnership); approach related to the classification of factors of customer choice of hospitality facilities (a sign of customer preferences); an approach based on the classification of factors related to the orientation of the place in the market environment (market sign). The key factors of hospitality development characteristic of the current stage of development are formulated, in particular: performance factors (or factors of critical influence), prognostic factors, partnership development factors, customer preferences factor, market factors.

Originality. The scientific novelty lies in the fact that the study further developed the question of classification of essential features and the composition of factors in the development of hospitality, which exist at the present stage of scientific thought.

Practical value. The practical significance of the results of the study is that the presented factors can be used for actual and predictive assessment of the development of the hospitality industry and its actors.
Key words: hospitality, efficiency, critical nature of influence, sign of partnership, market sign, customer preferences, segmentation, marketing analysis.
THE IMPACT OF HIGHLY SKILLED LABOUR MIGRATION ON HOST COUNTRIES (SWISS EXPERIENCE)
Authors: Bryk Mykhailo
Published: October 2022

Purpose. The aim of the article is systematization of theoretical approaches to the essence of international migration processes of highly qualified labour, as well as clarification of the impact of migration of highly qualified labour on host countries using the example of the Swiss economy.

Methodology of research. In the course of writing the article, the methods generally accepted in economic science were applied: theoretical and comparative analysis – to reveal the essence and meaning of migration processes; analysis and synthesis, grouping method – to determine the number of people, causes and consequences of emigration of the country’s population; abstract and logical ‒ for theoretical generalization and formulation of conclusions.

Findings. The consequences of immigration processes for the Swiss economy are studied. To understand the phenomenon of migration of highly qualified specialists, approaches to its definition are considered, including the theory of “brain drain”, which explains the negative consequences of the migration of highly qualified specialists in sending countries, the theory of “brain recruitment”, which describes the positive effects of this migration on receiving countries.

Originality. An assessment of the main causes and consequences of migration processes for the social and economic development of the country was carried out, a systematization of theoretical approaches to the essence of international migration processes of highly qualified labour force was carried out, and the impact of migration of highly qualified labour force on host countries was clarified using the example of the Swiss economy.

Practical value. The results of the conducted research can be used in the process of further implementation of deep social and economic reforms and radical institutional transformations in Ukraine, aimed at the formation of competitive advantages of the labour market and its effective functioning.

The use of international experience to improve the efficiency of the domestic labour market will have positive consequences for the national economy in the future.

Key words: highly qualified specialists, migration, integration, labour migration, migration processes, immigration, potential, workforce.
PECULIARITIES OF THE APPLICATION OF THE JOINT TRANSIT PROCEDURE IN THE CONTEXT OF THE STANDARDS OF INTERNATIONAL LEGISLATION
Authors: Tetiana Ruda
Published: October 2022

Purpose. The aim of the article is to study the main aspects of the international normative regulation of the application of the joint transit procedure.

Methodology of research. The following methods were used to achieve the goal: induction and deduction, theoretical generalization, abstraction, dialectical cognition – when studying scientific sources and legislation and researching theoretical aspects of the implementation of the joint transit procedure, determining the categorical apparatus of the investigated issues; abstract and logical – for summarizing theoretical propositions, forming conclusions.

Findings. The essence and features of the application of transit systems in the EU have been determined. In particular, the characteristics of joint and allied transit are given. The legal and regulatory framework that regulates issues related to the use of these transit systems is outlined. The advantages of countries joining the Convention on the common transit procedure are given, as well as the conditions for applying the common transit procedure are outlined. The peculiarities of the joint transit procedure have been analysed. Duties of transit subjects are outlined.

The essence, contents and functionality of the electronic transit system (New Computerised Transit System – NCTS) are disclosed. The characteristics of application programs developed by the EU with the aim of their implementation in countries that are not members of the EU, but are on the way to joining the Convention on the common transit procedure, are described. The process of exchanging customs information provided by NCTS and the security aspects of its preservation within the system are analysed. The advantages of the practical implementation of the electronic transit system in Ukraine are outlined.

Originality. The study of the theoretical aspects of the common transit procedure and the implementation of the electronic transit system (NCTS) in the activities of domestic customs authorities has gained further development.

Practical value. The main provisions of this study can be used in the process of developing proposals regarding the conceptual directions of reforming customs procedures in Ukraine.
Key words: transit, joint transit, allied transit, implementation of the common transit procedure, electronic transit system (NCTS).
ESSENCE AND ROLE OF STATE EXPENDITURES IN REGULATING THE DISTRIBUTION OF THE POPULATION’S INCOME
Authors: Tetiana Valihura
Published: October 2022

Purpose. The aim of the article is to generalize the theoretical approaches to determining the essence, classification and composition of state expenditures and substantiation of their role and mechanism in regulating the distribution of population income.

Methodology of research. The theoretical and methodological basis of the research is the fundamental provisions of financial science, set forth in the works of Ukrainian and foreign scientists on the issues of formation of state expenditures. The following general scientific and special methods were used in the research process: logical analysis, synthesis, theoretical generalization (in the process of distinguishing the concepts of “budget expenditures” and “budget costs”); induction, deduction, abstract and logical (when characterizing the essence of state expenditures, state purchases and social transfers); abstraction, description, comparison (to substantiate the mechanism of influence of state expenditures on improving the financial condition of the population).

Findings. It has been established that, in terms of economic essence, “budget expenditures” is a broader concept than “budget costs”, since they, under the conditions of exchange for the necessary value equivalent, can be turned into expenses. It is substantiated that public purchases and social transfers are a type of public expenditure. After all, the essence of public procurement consists in the allocation of budget funds for the purchase of goods and services necessary for the functioning of state and local authorities and the population.

Instead, social transfers by their content are a system of monetary or in-kind payments to the population that are not related to their participation in economic activity at the present time or in the past. A graphical interpretation of the mechanism of influence of state expenditures on the improvement of the financial condition of the population is presented.

Originality. Approaches to the classification of state expenditures have been improved. According to the method of influence on the financial condition of the population, it is proposed to divide expenses into those that directly improve the financial condition of the population, and those that improve the financial condition of the population through reproductive processes.

Practical value. The results of the presented research can be used in the process of forming and implementing financial policy in terms of the use of state expenditures to improve the financial condition of the population.
Keywords: state expenditures, state purchases, social transfers, population income distribution.
THE ROLE OF LOCAL TAXES AND FEES IN THE CONDITIONS OF DECENTRALIZATION
Authors: Yevhenii Shapovalov
Published: October 2022

Purpose. Research of the current state and main trends of local taxes and fees, their fiscal and regulatory role in the conditions of budget decentralization and the functioning of the new administrative-territorial system.

Methodology of research. The theoretical and methodological basis of the article is the fundamental provisions of modern economic science. In the research process, the following methods were used: theoretical generalization and scientific abstraction - when substantiating the categorical-conceptual research apparatus; the method of system analysis - in the formation of the theoretical and methodological base of the study and the structural structure of the study; the method of comparative analysis - when identifying patterns and main trends of local taxes in the conditions of fiscal decentralization, methods of descriptive statistics and visual analysis - for a visual presentation of the main provisions of the study and formulation of the relevant conclusions of the conducted study.

Findings. The indicators of receipts from local taxes and fees for the period from the beginning of budget decentralization to the beginning of 2022 were analyzed, the main trends in the receipt of these payments and changes in their structure were determined. A trend towards an increase in the specific weight of the tax on immovable property other than land in the structure of local taxes was established. The reasons for the increase in the share of the single tax in the structure of local taxes and fees was studied. The influence of revenues from the payment of local taxes and fees on the dynamics of monthly revenues to local budgets was determined.

Originality. The conceptual foundations of understanding the role of local taxes and fees in the conditions of fiscal decentralization are deepened. Scientific and methodical approaches to the analysis and knowledge of the revenue part of local budgets have been improved.

Practical value. The results of the research can be used by local self-government bodies and state authorities for further work with the rates of local taxes and fees, their administration in conditions of decentralization.
Key words: tax, local taxes, budget, decentralization, local budgets, territorial communities, local self-government budgets, property tax, single tax, fee for parking spaces for vehicles, tourist fee.
Financial Support of Natural Agricultural Production in Ukraine
Authors: Labenko Oleksandr , Dolzhenko Inna , Klymenko Maksym , Ilchuk Olena
Published: October 2022

The processes of modern globalization and social transformations have significantly increased the priority of environmental protection, accordingly, they require the implementation of priority measures to solve urgent problems in the field of environmental protection and the simultaneous rational use of natural resources. The solution to these problems significantly depends on the system of financial support formed in the countries, as well as the established composition and volumes of funding sources and the determined directions of their use, which determines the need for a scientifically based analysis. The purpose of the work is to study the innovation activity of Ukrainian enterprises by sources of their financing and the development of practical recommendations for choosing the optimal model of influence on innovation efficiency of innovation support. The methodological basis of the research was the use of a set of general scientific and special methods: generalizations and scientific abstraction, historical-logical, extrapolation, and tabular visualization methods. Results of the research - The system of financial support for environmental protection at the current stage of the development of the economy of Ukraine was investigated. It is noted that environmental taxes should not just fill the state budget of the country, but stimulate the payer to have a positive and responsible attitude towards the natural environment. The dynamics of revenues to the budgets due to the application of environmental taxation mechanisms was studied and a conclusion was drawn regarding its effectiveness. The effectiveness of the implementation of the fiscal and regulatory functions of the environmental tax in Ukraine was evaluated. The order of distribution of environmental tax funds, as the main source of replenishment of environmental funds, was considered and the inefficiency of its use was analyzed. It was established that the environmental tax does not fully fulfill its fiscal function because the received income does not allow for fully financed environmental protection measures. The obtained results can be used as a basis for reforming the environmental tax in the direction of increasing its fiscal and effective effectiveness.
O corpo-vivente: centro de orientação eu-mundo-outro
Authors: Maria Aparecida Viggiani Bicudo
Published: October 2022

Este artigo tem como pergunta norteadora: "como e por que o corpo vivente é assumido na fenomenologia husserliana enquanto centro orientador eu-mundo-outro?".  No intuito de perseguir a direção por ela indicada, toma-se por base os Capítulos Terceiro e Quarto do "Idee per uma Fenomenologia pura e per uma filosofia fenomenológica" volume II (Husserl, 2002, 2005), do parágrafo 35 ao 47. Entende-se que o estudo desse texto viabiliza a exposição das ideias que esse autor apresenta sobre o corpo-vivente, as quais abordam questões concernentes à fisicalidade do corpo, às suas dimensões psicofísicas, à constituição de valores, à constituição da intersubjetividade.
O Ecossistema do Esporte e a Materialidade do ESG
Authors: Mattana Camila , Bugarim André
Published: October 2022

A natureza, é, por si só, um chamado para a prática de esportes, porém, para que ocorra esta relação simbiótica e sustentável entre ambos, é preciso uma atenção quanto à responsabilidade solidária e individual de cada ator dessa interação. Do ponto de vista do ESG (ambiental, social e de governança), ao analisar o ecossistema do esporte, é possível verificar que não se trata apenas de uma relação entre atletas e torcedores. A materialidade do esporte vai além dos estádios, ginásios, piscinas e praças do desporto no geral, bem como o ciclo de vida de uma iniciativa esportiva é capaz de gerar milhares de oportunidades, sobretudo em relação a uma perspectiva econômica global, com compromissos e estratégias alinhados entre os seus stakeholders, a ponto de ser um benchmarking importante para o desenvolvimento sustentável de um país.
Governança Pública Humanizada: oportunidades para elevar o bem-estar social e a prosperidade sustentável
Authors: Canêdo Ramos Flávia Cristina , Lourenço Luana , Matias de Abreu Welles
Published: October 2022

O que a sociedade espera da atuação governamental? Por certo, se essa for a pergunta principal de uma pesquisa de opinião junto à população serão obtidas respostas bastante variáveis, a depender do respondente: diminuir a desigualdade social, garantir o exercício dos direitos constitucionais, cuidar do meio ambiente, solucionar falhas de mercado, melhorar a distribuição de renda, garantir a segurança física e patrimonial, saúde e educação, dentre outras temáticas. Observa-se, no entanto, que todas as respostas poderão ter por base um mesmo pano de fundo: as ações governamentais devem dar conta das demandas fundamentais populacionais, fazendo entregas eficazes (atingindo suas metas), efetivas (resolvendo de fato os problemas sociais) e eficientes (otimizando recursos).
Aus Prinzip kostensparend
Authors: Seiters Christina
Published: October 2022

Schon als das Braunschweiger Heidbergbad in den 1970er Jahren als Europabad errichtet wurde, standen intelligente, kostensparende Ideen im Mittelpunkt der Umsetzung. Ein Fokus, der bis heute erhalten geblieben ist, denn auch der mittlerweile realisierte Ersatzneubau überzeugt durch niedrige Energiekosten.
Rechtsscheinvollmachten
Authors: Voppel Reinhard
Published: October 2022

Immer wieder stellt sich die Frage, ob die Person, die einen Auftrag erteilt oder eine Änderungsanordnung trifft, dazu überhaupt bevollmächtigt ist. Im Einzelfall kann die Annahme einer Rechtsscheinvollmacht helfen.
Analisis Stabilitas Tanggul Penahan Tanah Pedestrian Zona II Situ Bagendit
Authors: Nurhuda Tiara
Published: October 2022

Abstract: Situ Bagendit is one of the natural tourism areas in Garut Regency with an area of 124 Ha. Besides being a tourist attraction, Bagendit Lake is also a suggestion for irrigation in the surrounding area. In addition to channeling irrigation, earth retaining embankments built together with pedestrians must also meet the safety requirements of stability. This study aims to determine the value of the safety factor of the Situ Bagendit embankment against slipping and overturning. To determine the value of stability, the forces and moments acting on the embankment and water are analyzed. The value of slip or shear stability is 1.73 and the value of rolling stability is 2.1, where the value is categorized as safe because it is more than 1.25. It was concluded that the Situ Bagendit II embankment was categorized as safe against sliding and overturning

Abstrak: Situ Bagendit merupakan salah satu kawasan wisata alam di Kabupaten Garut dengan luas 124 Ha. Selain menjadi objek wisata, situ Bagendit juga sebagai saran irigasi di daerah sekitar. Disamping untuk menyalur irigasu, tanggul penahan tanah dibangun bersamaan dengan pedestrian juga harus memenuhi persyaraytan aman dari stabilitas. Penelitian ini bertujuan untuk mengetahui nilai faktor aman tanggul Situ Bagendit terhadap gelincir dan guling. Untuk mengetahui nilai stabilitas maka dianalisis gaya-gaya dan momen yang bekerja pada tanggul dan air. Nilai stabilitas gelincir atau geser adalah 1,73 dan nilai stabilitas guling adalah 2,1, dimana nilai tersebut dikategorikan aman karena lebih dari 1,25. Dissipulkan bahwa tanggul Situ Bagendit II dikategorikan aman terhadap geser maupun guling
Employee Productivity Analysis in the Production Department at PT. "X"
Authors: Avrianto Alam , Gumilar Irfan Rizky
Published: October 2022

Productivity is an important aspect because it will affect the sustainability of an organization/company, as well as PT. X. Based on the results of data collection, it is seen that there is a decrease in production productivity shown by the amount of production that is below the target. The purpose of this research is to analyze the causes of the decline in productivity. This study uses quantitative and descriptive methods in measuring the dimensions of employee productivity where the research data used is population data which is all employees in the production section. Based on the results of the study, it is known that the decrease in productivity is caused by the poor attitude and behavior of employees at work. This is indicated by the presence of other movements in addition to the core movement in making products such as using a mobile phone, chatting, etc. at work. Although the majority of the dimensions can be said to be good but with the lack of good attitudes and behavior of employees, it has a very large influence on the productivity of the company.
Поперечники класів функцій у ваговому просторі

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Authors: Vakarchuk S. B.
Published: October 2022

УДК 517.5
У просторі

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досліджуються апроксимаційні характеристики оптимізаційного змісту для класів функцій

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та вказано умову на мажоранту, при виконанні якої вдається обчислити їх точні значення. Наведено декілька конкретизацій точних результатів.
Метод усереднення в задачі оптимального керування для збуреного параболічного рівняння
Authors: Kapustyan O. V. , Stanzhytskyi O. M. , Fartushny I. D.
Published: October 2022

УДК 517.9Розглядається задача оптимального керування, що складається з параболiчного нелiнiйного рiвняння з швидко коливними коефiцiєнтами й адитивним керуванням та коерцитивним функцiоналом вартостi. Доведено, що оптимальне значення збуреної задачi близьке до оптимального значення вiдповiдної задачi з усередненими коефiцiєнтами.
Оцiнка та досягнення зважених критерiїв якостi у дескрипторних системах керування
Authors: Mazko A. G.
Published: October 2022

УДК 517.925.51; 681.5.03Розглянуто клас лiнiйних дескрипторних систем керування з обмеженими збуреннями. Встановлено критерiй та достатнi умови iснування статичних регуляторiв, при яких замкнена система є допустимою i гарантується бажана оцiнка зваженого рiвня гасiння зовнiшнiх i початкових збурень. Запропоновано новi методи синтезу узагальнених

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-регуляторiв за станом, що зводяться до розв’язання лiнiйних матричних нерiвностей без додаткових обмежень.Для iлюстрацiї отриманих результатiв наведено приклад дескрипторної системи стабiлiзацiї електричного кола.
Effect of Partial Shading on the Performance of Various 4×4 PV Array Configurations
Authors: Narne Dharani Kumar , Kumar T. A. Ramesh , Alla Rama Koteswara Rao
Published: October 2022

Electrical energy usage has drastically increased in recent decades, resulting in significant demand for renewable energy sources, especially solar. With the development of technology, extracting energy from photovoltaic (PV) modules has become easier and more economical. The performance of PV array decreases under an intermittent environment such as partial shading conditions (PSCs), causing fluctuations in PV array power output. This paper presents the analysis of a 4×4 PV array configuration under different PSCs. The power output of PV array depends on factors such as the type of configuration, size of array, and shading patterns. The performance of various types of 4×4 PV array configurations under different shading situations are compared and analyzed in this study, and the results presented.
The relationship between ulcerative colitis activity and vitamin D, mean platelet volume and platelet distribution width
Authors: KAYA Mehmet Nur , YILDIZ Ayla
Published: October 2022

Aim: In our study, we aimed to show the relationship between ulcerative colitis activity and vitamin D, platelet distribution width, and mean platelet volume.

Material and Method: Our study was conducted at the Internal Medicine Clinic. We planned to cross-sectionally investigate the severity of ulcerative colitis activity, vitamin D level, mean platelet volume, platelet distribution width and other laboratory parameters of patients admitted to the hospital. The Truelove and Witts’ severity index was used to determine ulcerative colitis activity. In accordance with the guidelines, serum 25-OH vitamin D levels of >30 ng/ml were considered as sufficient vitamin D, 20-30 ng/ml as vitamin D insufficiency,
Effective Implementation of the Text-Based Approach in English Second Language Classrooms
Authors: Matiso Nomasomi Hilda , Makena Bulelwa
Published: October 2022

Effective implementation of the Text-based Approach in English Second Language (ESL) Classrooms is a grave component of the educational system. The main aim of this paper was to investigate the effective implementation of the Text-based Approach in grade 10 learners and to propose measures that could enhance its effective implementation. The study adopted an interpretive paradigm embedded in a qualitative approach. Semi-structured interviews were utilised to collect data from 12 conveniently selected participants. Content analysis was used to analyse data, which were categorised into themes. The findings of this paper revealed that factors that hinder the effective implementation of the Text-based Approach are inadequate knowledge of curriculum stipulations, language barrier, misunderstanding of the approach, and the disaggregation of the English language. The authors conclude that there is an urgent need for teachers to have upgraded and relevant language-learning methodologies, thereby recommending that the Department of Education should organise workshops for the teachers to familiarise them with the recent methods of language teaching and learning.

Keywords: Text-based Approach, Communicative competence, Language learning, Pedagogical content knowledge, Authentic texts
Ambipolar Diffusion in the Lower Solar Atmosphere: Magnetohydrodynamic Simulations of a Sunspot
Authors: MacBride Conor D. , Jess David B. , Khomenko Elena , Grant Samuel D. T.
Published: October 2022

Magnetohydrodynamic (MHD) simulations of the solar atmosphere are often performed under the assumption that the plasma is fully ionized. However, in the lower solar atmosphere a reduced temperature often results in only the partial ionization of the plasma. The interaction between the decoupled neutral and ionized components of such a partially ionized plasma produces ambipolar diffusion. To investigate the role of ambipolar diffusion in propagating wave characteristics in the photosphere and chromosphere, we employ the Mancha3D numerical code to model magnetoacoustic waves propagating through the atmosphere immediately above the umbra of a sunspot. We solve the nonideal MHD equations for data-driven perturbations to the magnetostatic equilibrium and the effect of ambipolar diffusion is investigated by varying the simulation to include additional terms in the MHD equations that account for this process. Analyzing the energy spectral densities for simulations with/without ambipolar diffusion, we find evidence to suggest that ambipolar diffusion plays a pivotal role in wave characteristics in the weakly ionized low density regions, hence maximizing the local ambipolar diffusion coefficient. As a result, we propose that ambipolar diffusion is an important mechanism that requires careful consideration into whether it should be included in simulations, and whether it should be utilized in the analysis and interpretation of particular observations of the lower solar atmosphere.
Environmental DNA metabarcoding is a promising method for assaying fish diversity in cenotes of the Yucatán Peninsula, Mexico
Authors: Alter S. Elizabeth , Arroyave Jairo
Published: October 2022

The karst aquifer of the Yucatán Peninsula (YP) in southeastern Mexico is a unique ecosystem in which water-filled sinkholes, locally known as cenotes, connect subterranean waters with the surface. This system is home to around 20 species of freshwater fishes, including several that are endemic and/or threatened. Studies on this unique ichthyofauna have been partially hampered by the technical difficulties associated with sampling these habitats, particularly submerged caves. In this proof-of-concept study, we use environmental DNA (eDNA) metabarcoding to survey the diversity of freshwater fishes associated with the YP karst aquifer by sampling six cenotes from across the Ring of Cenotes region in northwestern Yucatán, a 180-km-diameter semicircular band of abundant karst sinkholes. Through a combination of conventional sampling (direct observation, fishing) and eDNA metabarcoding, we detected eight species of freshwater fishes across the six sampled cenotes. Overall, our eDNA metabarcoding approach was effective at detecting the presence of fishes from cenote water samples, including one of the two endemic cave-dwelling fish species restricted to the subterranean section of the aquifer. Although our study was focused on detecting fishes via eDNA, we also recovered DNA from several other vertebrate groups, particularly bats. These results suggest that the eDNA metabarcoding approach represents a promising and largely noninvasive method to assay aquatic biodiversity in these vulnerable habitats, allowing more effective, frequent, and wide-ranging surveys. Our detection of DNA from aerial and terrestrial vertebrate fauna implies that eDNA from cenotes, besides being a means to survey aquatic fauna, may also offer an effective way to quickly survey non-aquatic biodiversity associated with these persistent water bodies.
Resurrection of Pleurospermum lecomteanum H.Wolff (Apiaceae) based on molecular and morphological evidence
Authors: Zhou Jing , Niu Junmei , Wang Xinyue , Zhou Shilin , Liu Zhenwen
Published: October 2022

The taxonomic placement of Pleurospermum lecomteanum, previously synonymized with Pleurospermum wilsonii, was carefully examined using herbarium specimens and molecular evidence. The results showed that Pleurospermum lecomteanum is distinguished from P. wilsonii by several morphological characters. Its phylogenetic position is separate from P. wilsonii in the ML tree. Therefore, Pleurospermum lecomteanum should be restored as a distinct species.
Association between serum ferritin levels and colorectal cancer risk in Korea
Authors: Kim Hyunho , Han Kyungdo , Ko Seung-Hyun , An Ho Jung
Published: October 2022

Background/Aims: The concentration of serum ferritin, a storage form of iron, may be associated with carcinogenesis in various cancers. There are only limited studies on the relationship between serum ferritin levels and colorectal cancer (CRC) risk, especially in the Asian population. This study aimed to analyze the association between CRC incidence and serum ferritin levels.Methods: This was a national cohort study that used health checkup and insurance claims data of the Korean population. CRC incidence according to the serum ferritin level was analyzed during 2008–2018 in 17,116 participants.Results: The hazard ratio (HR) of CRC incidence decreased as serum ferritin levels increased (Q1: HR, 1.000 [95% confidence interval [CI], reference]; Q2: HR, 0.811 [95% CI, 0.558 to 1.178]; Q3: HR, 0.654 [95% CI, 0.442 to 0.968]; Q4: HR, 0.443 [95% CI, 0.285 to 0.687]; p = 0.0026). In subgroup analysis, 40 to 64 years of age, sex, body mass index of < 25 kg/ m2, presence of metabolic syndrome, absence of diabetes mellitus, and absence of anemia had HRs of < 0.5 (95% CI) in the highest quartiles compared with that in the lowest quartiles.Conclusions: This study shows an inverse association between serum ferritin and CRC risk. Serum ferritin measurement can aid in identifying young adults requiring active CRC screening.
La modélisation cartographique des controverses, un outil au service de l’esprit critique ?
Authors: Desfriches Doria Orélie
Published: October 2022

L’objet de l’article vise à présenter un retour réflexif sur les acquisitions des étudiants, en matière d’esprit critique, lors d’expérimentations pédagogiques autour d’enseignements sur l’analyse des controverses. Nous abordons les apports des SIC à ce champ de recherches, notamment sur la considération du rôle des médias et des publics dans l’étude des controverses et la diversification des objectifs des enseignements de controverses. Nous décrivons notre cadre théorique d’appréhension de l’objet « controverse » et notre approche originale d’analyse des controverses (MASCO). Un focus est ensuite proposé sur les liens entre cartographie et modélisation dans l’optique de préciser un autre apport des SIC aux études de controverses. Par la suite, nous présentons l’analyse de résultats partiels de l’évaluation de l’enseignement expérimental que nous dispensons. Nous terminons en discutant les méthodologies d’évaluation de ces enseignements de l’esprit critique par les controverses.
Les signes à l’épreuve des systèmes de croyance
Authors: Saemmer Alexandra , Tréhondart Nolwenn
Published: October 2022

Suivant l’idée que l’éducation aux médias et à l’information constitue à la fois un champ de recherche théorique et une praxis pédagogique, nous présentons, dans cet article, une démarche critique en sémiotique sociale que nous développons sur différents terrains depuis plusieurs années (photographies d’actualité, sites de presse en ligne, séries, livres numériques, plateformes sociales). Après un rapide état de l’art consacré aux conceptualisations de la « réflexivité », nous nous pencherons sur deux objets centraux actuellement dans l’éducation aux médias — les réseaux sociaux et l’image d’actualité — en montrant comment cette démarche de recherche transposée en contexte pédagogique permet d’engager l’apprenant.e et l’enseignant.e dans un processus de co-construction réflexif des significations, qui permet de compléter les méthodes de décryptage classique par une prise de conscience quant au rôle joué par les habitudes, normes, allants de soi et croyances dans la production du sens.
Carnet de controverses en temps de Covid : pour une autre communication de crise en santé
Authors: Zacklad Manuel
Published: October 2022

Dans cet article nous présentons une enquête qui croise ethnographie en ligne et ethnographie engagée sur le réseau LinkedIn. Nous commençons par présenter une typologie « anthropo-épistémique » des postures de recherche pour préciser l’approche qui est la nôtre dans l’étude des groupes subalternes que nous avons observés sur ce réseau social. Nous décrivons ensuite quatre espaces de controverses actifs liés à la gestion de la crise du Covid-19 et à la communication à son égard : controverses liées à l’importance de l’épidémie, à l’interdiction des traitements, à la pertinence des mesures sociales telles que confinement national et couvre-feux et enfin, l’imposition des passes sanitaire et vaccinal. L’analyse de ces controverses, dont les protagonistes sont souvent des experts du domaine sans rapport avec la vision caricaturale du complotiste ignare et malfaisant, montre que les méthodes classiques de communication en santé, basées sur des méthodes persuasives, sont inopérantes et tendent même à produire l’effet inverse de celui recherché. Nous plaidons pour une « communication de crise épistémique » fondée sur l’intelligence coopérative du public, des médiateurs, des spécialistes et des scientifiques, qui ouvre des espaces d’expérimentation et de débat à toutes les échelles où les échanges sont possibles.
Management of Psychiatric Phenomena in Lewy Body Dementia
Authors: Hinkle Jared T. , Pontone Gregory M.
Published: October 2022

Lewy body dementia (LBD) encompasses both dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD). These forms of dementia are pathologically related by the findings of Lewy body neuronal inclusions. Patients with either disease are commonly faced with psychiatric symptoms such as psychosis, depression, and anxiety. This review discusses the similarities and differences between PDD and DLB with respect to the phenomenology, management, and impact of key psychiatric manifestations. An important overarching theme is that most pharmacologic options available to practitioners are of generally modest benefit and require important consideration for the potential to worsen other symptoms. Thus, patients require careful monitoring and reassessment, as well as counseling on nonpharmacologic strategies and support for caregiver burden.

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Psychiatr Ann
. 2022;52(10):410–414.]
Brief Psychotic Episode After Vitamin C Overdose Due to Fear of Getting COVID-19
Authors: Gökçay Hasan , Köse Hüseyin , Ağaç Talha , Solmaz Mustafa
Published: October 2022

Coronavirus infection (COVID-19) caused by the new coronavirus SARSCoV-2 is a global public health problem. Ascorbic acid (vitamin C) is low-cost, safe, antioxidant, anti-inflammatory, and immunomodulating, and has viral load-reducing effects when taken as a supplement. In addition, vitamin C neutralizes free radicals and protects the body against cellular damage, and it can provide a protective effect against cardiovascular diseases by regulating the production of free radicals via nitric oxide. This situation makes ascorbic acid a notable treatment candidate for preventing the worsening of COVID-19. In our case, we present a patient who had a brief psychotic episode following ingestion of high-dose vitamin C due to fear of getting infected with SARS-CoV-2. The psychotic episode may have developed due to increased levels of circulating vitamin C in the central nervous system, which may affect dopamine and GABA levels and changes in NMDA receptor function in the brain. We aim to draw attention to possible neurotoxicity and inflammation caused by free radicals on neuropsychiatric diseases.

[
Psychiatr Ann
. 2022;52(10):442–444.]