bluuebunny/crossref_metadata_2025 huggingface dataset:
ABC transporter mis-splicing associated with resistance to Bt toxin Cry2Ab in laboratory- and field-selected pink bollworm
Authors: Mathew Lolita G. , Ponnuraj Jeyakumar , Mallappa Bheemanna , Chowdary Lingutla R. , Zhang Jianwei , Tay Wee Tek , Walsh Thomas K. , Gordon Karl H. J. , Heckel David G. , Downes Sharon , Carrière Yves , Li Xianchun , Tabashnik Bruce E. , Fabrick Jeffrey A.
Published: September 2018

Evolution of pest resistance threatens the benefits of genetically engineered crops that produce Bacillus thuringiensis (Bt) insecticidal proteins. Strategies intended to delay pest resistance are most effective when implemented proactively. Accordingly, researchers have selected for and analyzed resistance to Bt toxins in many laboratory strains of pests before resistance evolves in the field, but the utility of this approach depends on the largely untested assumption that laboratory- and field-selected resistance to Bt toxins are similar. Here we compared the genetic basis of resistance to Bt toxin Cry2Ab, which is widely deployed in transgenic crops, between laboratory- and field-selected populations of the pink bollworm (Pectinophora gossypiella), a global pest of cotton. We discovered that resistance to Cry2Ab is associated with mutations disrupting the same ATP-binding cassette transporter gene (PgABCA2) in a laboratory-selected strain from Arizona, USA, and in field-selected populations from India. The most common mutation, loss of exon 6 caused by alternative splicing, occurred in resistant larvae from both locations. Together with previous data, the results imply that mutations in the same gene confer Bt resistance in laboratory- and field-selected strains and suggest that focusing on ABCA2 genes may help to accelerate progress in monitoring and managing resistance to Cry2Ab.
Influence of internal climate variability on Indian Ocean Dipole properties
Authors: Ng Benjamin , Cai Wenju , Cowan Tim , Bi Daohua
Published: September 2018

The Indian Ocean Dipole (IOD) is the dominant mode of interannual variability over the tropical Indian Ocean (IO) and its future changes are projected to impact the climate and weather of Australia, East Africa, and Indonesia. Understanding the response of the IOD to a warmer climate has been largely limited to studies of individual coupled general circulation models or multi-model ensembles. This has provided valuable insight into the IOD’s projected response to increasing greenhouse gases but has limitations in accounting for the role of internal climate variability. Using the Community Earth System Model Large Ensemble (CESM-LE), the IOD is examined in thirty-five present-day and future simulations to determine how internal variability influences properties of the IOD and their response to a warmer climate. Despite small perturbations in the initial conditions as the only difference between ensemble members, significant relationships between the mean state of the IO and the IOD arise, leading to a spread in the projected IOD responses to increasing greenhouse gases. This is driven by the positive Bjerknes feedback, where small differences in mean thermocline depth, which are caused by internal climate variability, generate significant variations in IOD amplitude, skewness, and the climatological zonal sea surface temperature gradient.
A multi-cellular 3D bioprinting approach for vascularized heart tissue engineering based on HUVECs and iPSC-derived cardiomyocytes
Authors: Maiullari Fabio , Costantini Marco , Milan Marika , Pace Valentina , Chirivì Maila , Maiullari Silvia , Rainer Alberto , Baci Denisa , Marei Hany El-Sayed , Seliktar Dror , Gargioli Cesare , Bearzi Claudia , Rizzi Roberto
Published: September 2018

The myocardium behaves like a sophisticated orchestra that expresses its true potential only if each member performs the correct task harmonically. Recapitulating its complexity within engineered 3D functional constructs with tailored biological and mechanical properties, is one of the current scientific priorities in the field of regenerative medicine and tissue engineering. In this study, driven by the necessity of fabricating advanced model of cardiac tissue, we present an innovative approach consisting of heterogeneous, multi-cellular constructs composed of Human Umbilical Vein Endothelial Cells (HUVECs) and induced pluripotent cell-derived cardiomyocytes (iPSC-CMs). Cells were encapsulated within hydrogel strands containing alginate and PEG-Fibrinogen (PF) and extruded through a custom microfluidic printing head (MPH) that allows to precisely tailor their 3D spatial deposition, guaranteeing a high printing fidelity and resolution. We obtained a 3D cardiac tissue compose of iPSC-derived CMs with a high orientation index imposed by the different defined geometries and blood vessel-like shapes generated by HUVECs which, as demonstrated by in vivo grafting, better support the integration of the engineered cardiac tissue with host’s vasculature.
Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3
Authors: Kawane Tetsuya , Qin Xin , Jiang Qing , Miyazaki Toshihiro , Komori Hisato , Yoshida Carolina Andrea , Matsuura-Kawata Viviane Keiko dos Santos , Sakane Chiharu , Matsuo Yuki , Nagai Kazuhiro , Maeno Takafumi , Date Yuki , Nishimura Riko , Komori Toshihisa
Published: September 2018

Runx2 and Sp7 are essential transcription factors for osteoblast differentiation. However, the molecular mechanisms responsible for the proliferation of osteoblast progenitors remain unclear. The early onset of Runx2 expression caused limb defects through the Fgfr1–3 regulation by Runx2. To investigate the physiological role of Runx2 in the regulation of Fgfr1–3, we compared osteoblast progenitors in Sp7−/− and Runx2−/− mice. Osteoblast progenitors accumulated and actively proliferated in calvariae and mandibles of Sp7−/− but not of Runx2−/− mice, and the number of osteoblast progenitors and their proliferation were dependent on the gene dosage of Runx2 in Sp7−/− background. The expression of Fgfr2 and Fgfr3, which were responsible for the proliferation of osteoblast progenitors, was severely reduced in Runx2−/− but not in Sp7−/− calvariae. Runx2 directly regulated Fgfr2 and Fgfr3, increased the proliferation of osteoblast progenitors, and augmented the FGF2-induced proliferation. The proliferation of Sp7−/− osteoblast progenitors was enhanced and strongly augmented by FGF2, and Runx2 knockdown reduced the FGF2-induced proliferation. Fgfr inhibitor AZD4547 abrogated all of the enhanced proliferation. These results indicate that Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation, at least partly, by regulating Fgfr2 and Fgfr3 expression.
Studying the integrated functional cognitive basis of sustained attention with a Primed Subjective-Illusory-Contour Attention Task
Authors: Cowley Benjamin Ultan
Published: September 2018

Sustained attention plays an important role in everyday life, for work, learning, or when affected by attention disorders. Studies of the neural correlates of attention commonly treat sustained attention as an isolated construct, measured with computerized continuous performance tests. However, in any ecological context, sustained attention interacts with other executive functions and depends on lower level perceptual processing. Such interactions occur, for example, in inhibition of interference, and processing of complex hierarchical stimuli; both of which are important for successful ecological attention. Motivated by the need for more studies on neural correlates of higher cognition, I present an experiment to investigate these interactions of attention in 17 healthy participants measured with high-resolution electroencephalography. Participants perform a novel 2-alternative forced-choice computerised performance test, the Primed Subjective Illusory Contour Attention Task (PSICAT), which presents gestalt-stimuli targets with distractor primes to induce interference inhibition during complex-percept processing. Using behavioural and brain-imaging analyses, I demonstrate the novel result that task-irrelevant incongruency can evoke stronger behavioural and neural responses than the task-relevant stimulus condition; a potentially important finding in attention disorder research. PSICAT is available as an open-source code repository at the following url, allowing researchers to reuse and adapt it to their requirements. https://github.com/zenBen/Kanizsa_Prime/.
Hybrid System of an Optical Nanofibre and a Single Quantum Dot Operated at Cryogenic Temperatures
Authors: Shafi K. Muhammed , Luo Wei , Yalla Ramachandrarao , Iida Kazunori , Tsutsumi Emi , Miyanaga Akiharu , Hakuta Kohzo
Published: September 2018

Recent progress in quantum nanophotonics brings novel ways for manipulating single photons in various nano-waveguides. Among them, one promising approach is to use optical nanofibres (ONFs), tapered optical fibres with sub-wavelength diameter waists. Here, we develop a hybrid system of an ONF and a single quantum dot (QD) operated at cryogenic temperatures. We deposit a single colloidal CdSe QD on an ONF waist and observe emitted photons through the fibre guided modes. We systematically investigate emission characteristics for both the neutral exciton and charged exciton (trion) for one specific QD. We quantitatively show that the trion at cryogenic temperatures acts as an excellent quantum emitter for the ONF and QD hybrid system. The present ONF/QD hybrid system at cryogenic temperatures paves the way for quantum information technologies for manipulating single photons in fibre networks.
Meaning Guides Attention during Real-World Scene Description
Authors: Henderson John M. , Hayes Taylor R. , Rehrig Gwendolyn , Ferreira Fernanda
Published: September 2018

Intelligent analysis of a visual scene requires that important regions be prioritized and attentionally selected for preferential processing. What is the basis for this selection? Here we compared the influence of meaning and image salience on attentional guidance in real-world scenes during two free-viewing scene description tasks. Meaning was represented by meaning maps capturing the spatial distribution of semantic features. Image salience was represented by saliency maps capturing the spatial distribution of image features. Both types of maps were coded in a format that could be directly compared to maps of the spatial distribution of attention derived from viewers’ eye fixations in the scene description tasks. The results showed that both meaning and salience predicted the spatial distribution of attention in these tasks, but that when the correlation between meaning and salience was statistically controlled, only meaning accounted for unique variance in attention. The results support theories in which cognitive relevance plays the dominant functional role in controlling human attentional guidance in scenes. The results also have practical implications for current artificial intelligence approaches to labeling real-world images.
A comparative analysis of approaches to network-dismantling
Authors: Wandelt Sebastian , Sun Xiaoqian , Feng Daozhong , Zanin Massimiliano , Havlin Shlomo
Published: September 2018

Estimating, understanding, and improving the robustness of networks has many application areas such as bioinformatics, transportation, or computational linguistics. Accordingly, with the rise of network science for modeling complex systems, many methods for robustness estimation and network dismantling have been developed and applied to real-world problems. The state-of-the-art in this field is quite fuzzy, as results are published in various domain-specific venues and using different datasets. In this study, we report, to the best of our knowledge, on the analysis of the largest benchmark regarding network dismantling. We reimplemented and compared 13 competitors on 12 types of random networks, including ER, BA, and WS, with different network generation parameters. We find that network metrics, proposed more than 20 years ago, are often non-dominating competitors, while many recently proposed techniques perform well only on specific network types. Besides the solution quality, we also investigate the execution time. Moreover, we analyze the similarity of competitors, as induced by their node rankings. We compare and validate our results on real-world networks. Our study is aimed to be a reference for selecting a network dismantling method for a given network, considering accuracy requirements and run time constraints.
Radiomics of US texture features in differential diagnosis between triple-negative breast cancer and fibroadenoma
Authors: Lee Si Eun , Han Kyunghwa , Kwak Jin Young , Lee Eunjung , Kim Eun-Kyung
Published: September 2018

Triple-negative breast cancer (TNBC) is sometimes mistaken for fibroadenoma due to its tendency to show benign morphology on breast ultrasound (US) albeit its aggressive nature. This study aims to develop a radiomics score based on US texture analysis for differential diagnosis between TNBC and fibroadenoma, and to evaluate its diagnostic performance compared with pathologic results. We retrospectively included 715 pathology-proven fibroadenomas and 186 pathology-proven TNBCs which were examined by three different US machines. We developed the radiomics score by using penalized logistic regression with a least absolute shrinkage and selection operator (LASSO) analysis from 730 extracted features consisting of 14 intensity-based features, 132 textural features and 584 wavelet-based features. The constructed radiomics score showed significant difference between fibroadenoma and TNBC for all three US machines (p < 0.001). Although the radiomics score showed dependency on the type of US machine, we developed more elaborate radiomics score for a subgroup in which US examinations were performed with iU22. This subsequent radiomics score also showed good diagnostic performance, even for BI-RADS category 3 or 4a lesions (AUC 0.782) which were presumed as probably benign or low suspicious of malignancy by radiologists. It was expected to assist radiologist’s diagnosis and reduce the number of invasive biopsies, although US standardization should be overcome before clinical application.
Exogenous application of calcium to 24-epibrassinosteroid pre-treated tomato seedlings mitigates NaCl toxicity by modifying ascorbate–glutathione cycle and secondary metabolites
Authors: Ahmad Parvaiz , Abd_Allah Elsayed Fathi , Alyemeni Mohammed Nasser , Wijaya Leonard , Alam Pravej , Bhardwaj Renu , Siddique Kadambot H. M.
Published: September 2018

The present study tested the efficacy of 24-epibrassinolide (EBL) and calcium (Ca) for mediating salinity tolerance in tomato. Salinity stress affected the morphological parameters of tomato as well as leaf relative water content (LRWC), photosynthetic and accessory pigments, leaf gas exchange parameters, chlorophyll fluorescence and the uptake of essential macronutrients. The salt (NaCl) treatment induced oxidative stress in the form of increased Na+ ion concentration by 146%, electrolyte leakage (EL) by 61.11%, lipid peroxidation (MDA) 167% and hydrogen peroxide (H2O2) content by 175%. Salt stress also enhanced antioxidant enzyme activities including those in the ascorbate–glutathione cycle. Plants treated with EBL or Ca after salt exposure mitigated the ill effects of salt stress, including oxidative stress, by reducing the uptake of Na+ ions by 52%. The combined dose of EBL + Ca reversed the salt-induced changes through an elevated pool of enzymes in the ascorbate–glutathione cycle, other antioxidants (superoxide dismutase, catalase), and osmoprotectants (proline, glycine betaine). Exogenously applied EBL and Ca help to optimize mineral nutrient status and enable tomato plants to tolerate salt toxicity. The ability of tomato plants to tolerate salt stress when supplemented with EBL and Ca was attributed to modifications to enzymatic and non-enzymatic antioxidants, osmolytes and metabolites.
Electronic and Hydrogen Storage Properties of Li-Terminated Linear Boron Chains Studied by TAO-DFT
Authors: Seenithurai Sonai , Chai Jeng-Da
Published: September 2018

It has been extremely difficult for conventional computational approaches to reliably predict the properties of multi-reference systems (i.e., systems possessing radical character) at the nanoscale. To resolve this, we employ thermally-assisted-occupation density functional theory (TAO-DFT) to predict the electronic and hydrogen storage properties of Li-terminated linear boron chains (Li2Bn), with n boron atoms (n = 6, 8, …, and 16). From our TAO-DFT results, Li2Bn, which possess radical character, can bind up to 4 H2 molecules per Li, with the binding energies in the desirable regime (between 20 and 40 kJ/mol per H2). The hydrogen gravimetric storage capacities of Li2Bn range from 7.9 to 17.0 wt%, achieving the ultimate goal of the United States Department of Energy. Accordingly, Li2Bn could be promising media for storing and releasing H2 at temperatures much higher than the boiling point of liquid nitrogen.
Modified Bethesda system informing cytopathologic adequacy improves malignancy risk stratification in nodules considered benign or atypia(follicular lesion) of undetermined significance
Authors: Lee You-Bin , Kim Ji-Ye , Cho Haeyon , Hahn Soo Yeon , Shin Jung Hee , Lee Seung-Eun , Jun Ji Eun , Kim Sun Wook , Chung Jae Hoon , Kim Tae Hyuk , Oh Young Lyun
Published: September 2018

We modified the nondiagnostic/unsatisfactory category of the Bethesda system for reporting thyroid cytopathology to inform cytopathologic adequacy to better stratify the malignancy risk. Malignancy rates from 1,450 cytopathologic specimens not satisfying adequacy criteria from April 2011 to March 2016 were calculated based on sub-classification of the nondiagnostic/unsatisfactory category and sonographic patterns using matched surgical pathology. Rates were compared with those of 1,446 corresponding adequate specimens from July to December 2013. Upon resection, 63.2% of nondiagnostic, 36.7% of unsatisfactory + benign, 72.5% of unsatisfactory + atypia (follicular lesion) of undetermined significance, 98.1% of unsatisfactory + suspicious for malignancy, and 100.0% of unsatisfactory + malignant cases were confirmed to be malignant on surgical pathology. In nodules with inadequate specimens, those with high suspicion sonographic patterns had a malignancy rate (93.2%) higher than the others (45.5%) (p < 0.001). Nodules with unsatisfactory + benign specimens had a higher malignancy rate (36.7%) than satisfactory benign specimens (14.3%) (p = 0.020). For atypia (follicular lesion) of undetermined significance, the malignancy rate of inadequate specimens (72.5%) was higher than that of adequate specimens (51.3%) (p = 0.027). Sparse cellular samples with a few groups of benign follicular cells should not represent a benign lesion. There might be value in qualifying atypia (follicular lesion) of undetermined significance cases less than optimal.
Viral infections in fire ants lead to reduced foraging activity and dietary changes
Authors: Hsu Hung-Wei , Chiu Ming-Chung , Shoemaker DeWayne , Yang Chin-Cheng Scotty
Published: September 2018

Despite the presence of conserved innate immune function, many insects have evolved a variety of mechanical, chemical, and behavioral defensive responses to pathogens. Illness-induced anorexia and dietary changes are two behavioral defensive strategies found in some solitary insects, but little is known regarding the role of such behaviors in social insects, especially in ants. In the present study we examined if such reduced foraging activity exists for a social insect, the invasive fire ant Solenopsis invicta, and its viral pathogen, Solenopsis invicta virus 1 (SINV-1). Virus-free fire ant colonies were split into two colony fragments, one of which subsequently was inoculated with SINV-1. Four food resources with different macronutrient ratios were presented to both colony fragments. SINV-1-inoculated colony fragments consistently displayed reduced foraging performance (e.g., foraging intensity and recruitment efficiency), a decline in lipid intake, and a shift in dietary preference to carbohydrate-rich foods compared with virus-free fragments. These findings provide the first evidence for virus-induced behavioral responses and dietary shifts in shaping the host-pathogen interactions in fire ants. The findings also suggest a possible mechanism for how fire ant colonies respond to viral epidemics. Potential implications of these behavioral differences for current management strategies are discussed.
RETRACTED ARTICLE: Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats
Authors: Magar Shital , Nayak Deepika , Mahajan Umesh B. , Patil Kalpesh R. , Shinde Sachin D. , Goyal Sameer N. , Swaminarayan Shivang , Patil Chandragouda R. , Ojha Shreesh , Kundu Chanakya Nath
Published: September 2018

Despite the availability of multiple therapeutic agents, the search for novel pain management of neuropathic pain is still a challenge. Oxidative stress and inflammatory signaling are prominently involved in clinical manifestation of neuropathic pain. Toxicodendron pubescens, popularly known as Rhus Tox (RT) is recommended in alternative medicines as an anti-inflammatory and analgesic remedy. Earlier, we reported anti-inflammatory, anti-arthritic and immunomodulatory activities of Rhus Tox. In continuation, we evaluated antinociceptive efficacy of Rhus Tox in the neuropathic pain and delineated its underlying mechanism. Initially, in-vitro assay using LPS-mediated ROS-induced U-87 glioblastoma cells was performed to study the effect of Rhus Tox on reactive oxygen species (ROS), anti-oxidant status and cytokine profile. Rhus Tox decreased oxidative stress and cytokine release with restoration of anti-oxidant systems. Chronic treatment with Rhus Tox ultra dilutions for 14 days ameliorated neuropathic pain revealed as inhibition of cold, warm and mechanical allodynia along with improved motor nerve conduction velocity (MNCV) in constricted nerve. Rhus Tox decreased the oxidative and nitrosative stress by reducing malondialdehyde (MDA) and nitric oxide (NO) content, respectively along with up regulated glutathione (GSH), superoxide dismutase (SOD) and catalase activity in sciatic nerve of rats. Notably, Rhus Tox treatment caused significant reductions in the levels of tumor necrosis factor (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β) as compared with CCI-control group. Protective effect of Rhus Tox against CCI-induced sciatic nerve injury in histopathology study was exhibited through maintenance of normal nerve architecture and inhibition of inflammatory changes. Overall, neuroprotective effect of Rhus Tox in CCI-induced neuropathic pain suggests the involvement of anti-oxidative and anti-inflammatory mechanisms.
T cell immunomodulation by clinically used allogeneic human cancellous bone fragments: a potential novel immunotherapy tool
Authors: El-Sherbiny Yasser M. , El-Jawhari Jehan J. , Moseley Timothy A. , McGonagle Dennis , Jones Elena
Published: September 2018

Multipotential stromal cells (MSCs) demonstrate strong immunomodulation capabilities following culture expansion. We have previously demonstrated that human cancellous bone fragments (CBFs) clinically used as viable allografts for spinal fusion have resident MSCs that exhibit T cell immunomodulation after monolayer expansion. This study investigated the immunomodulatory ability of these CBFs without MSC culture-expansion. CD4 positive T cells were induced to proliferate using CD3/CD28 stimulation and added to CBFs at different ratios of T cells per gram of CBF. A dose-dependent suppressive effect on T cell proliferation was evident and correlated with increased culture supernatant levels of TGF-ß1, but not PGE2. CBF-driven immunosuppression was reduced in co-cultures with TGF-ß neutralising antibodies and was higher in cell contact compared to non-contact cultures. CBF gene expression profile identified vascular cell adhesion molecule-1, bone marrow stromal antigen 2/CD317 and other interferon signalling pathway members as potential immunomodulatory mediators. The CD317 molecule was detected on the surface of CBF-resident cells confirming the gene expression data. Taken together, these data demonstrate that human clinically used CBFs are inherently immunomodulatory and suggest that these viable allografts may be used to deliver therapeutic immunomodulation for immune-related diseases.
Radial trunk-centred reference frame in haptic perception
Authors: Dupin Lucile , Hayward Vincent , Wexler Mark
Published: September 2018

The shape of objects is typically identified through active touch. The accrual of spatial information by the hand over time requires the continuous integration of tactile and movement information. Sensory inputs arising from one single sensory source gives rise to an infinite number of possible touched locations in space. This observation raises the question of the determination of a common reference frame that might be employed by humans to resolve spatial ambiguity. Here, we employ a paradigm where observers reconstruct the spatial attributes of a triangle from tactile inputs applied to a stationary hand correlated with the voluntary movements of the other hand. We varied the orientation of the hands with respect to one another and to the trunk, and tested three distinct hypotheses regarding a reference frame used for integration: a hand-centred, a trunk-centred or an allocentric reference frame. The results indicated strongly that the integration of movement information and tactile inputs was performed in a radial trunk-centred reference frame.
Transcriptomic analysis of left-right differences in human embryonic forebrain and midbrain
Authors: de Kovel Carolien G. F. , Lisgo Steven N. , Francks Clyde
Published: September 2018

Left-right asymmetry is subtle but pervasive in the human central nervous system. This asymmetry is initiated early during development, but its mechanisms are poorly known. Forebrains and midbrains were dissected from six human embryos at Carnegie stages 15 or 16, one of which was female. The structures were divided into left and right sides, and RNA was isolated. RNA was sequenced with 100 base-pair paired ends using Illumina Hiseq 4000. After quality control, five paired brain sides were available for midbrain and forebrain. A paired analysis between left- and right sides of a given brain structure across the embryos identified left-right differences. The dataset, consisting of Fastq files and a read count table, can be further used to study early development of the human brain.
Design of a simple paper-based colorimetric biosensor using polydiacetylene liposomes for neomycin detection
Authors: Kang Do Hyun , Kim Keesung , Son Younghwan , Chang Pahn-Shick , Kim Jinsang , Jung Ho-Sup
Published: September 2018

A paper-based analytical device (μPAD) combined with self-signaling polydiacetylene liposomes was developed for convenient visual neomycin detection.
A novel bisphenol A electrochemical sensor based on a molecularly imprinted polymer/carbon nanotubes-Au nanoparticles/boron-doped ordered mesoporous carbon composite
Authors: Hu Xiaopeng , Feng Yingying , Wang Hao , Zhao Faqiong , Zeng Baizhao
Published: September 2018

An electrochemical sensor for bisphenol A was prepared based on molecularly imprinted polymer/carbon nanotubes-Au nanoparticles/boron-doped mesoporous carbon composite.
Facile synthesis of a metal–organic framework nanocarrier for NIR imaging-guided photothermal therapy
Authors: Li Yawei , Xu Na , Zhou Junli , Zhu Wenhe , Li Letian , Dong Mingxin , Yu Haotian , Wang Lei , Liu Wensen , Xie Zhigang
Published: September 2018

Near infrared Cy dye was efficiently embedded into zeolitic imidazolate framework-8 by a facile route for further using in the imaging-guided photothermal therapy.
Cyclic OFF/Part/ON switching of single-molecule magnet behaviours via multistep single-crystal-to-single-crystal transformation between discrete Fe(ii)–Dy(iii) complexes
Authors: Chen Wen-Bin , Chen Yan-Cong , Huang Guo-Zhang , Liu Jun-Liang , Jia Jian-Hua , Tong Ming-Liang
Published: September 2018

Multistep single-crystal-to-single-crystal transformation modulates OFF/Part/On single-molecule magnet behaviours for three discrete Fe(ii)–Dy(iii) complexes.
Fe-Catalyzed three-component carboazidation of alkenes with alkanes and trimethylsilyl azide
Authors: Li Wei-Yu , Wu Chuan-Shuo , Wang Zhou , Luo Yang
Published: September 2018

Iron out the difference. Carboazidation of alkenes using cycloalkanes, CH2Cl2, CHCl3and CCl4as alkylating reagents proceeded smoothly in the presence of TMSN3, DTBP and a catalytic amount of Fe(acac)3to afford chain extended alkyl azides and γ-azido chloroalkanes in good to high yields.
Organocatalytic decarboxylative alkylation of N-hydroxy-phthalimide esters enabled by pyridine-boryl radicals
Authors: Gao Liuzhou , Wang Guoqiang , Cao Jia , Yuan Dandan , Xu Cheng , Guo Xuewen , Li Shuhua
Published: September 2018

The decarboxylative alkylation of N-hydroxyphthalimide (NHPI) based reactive esters with olefins has been achieved via an organocatalytic strategy.
A water-stable homochiral luminescent MOF constructed from an achiral acylamide-containing dicarboxylate ligand for enantioselective sensing of penicillamine
Authors: Zhang Qingfu , Lei Mingyuan , Kong Fang , Yang Yan
Published: September 2018

A water-stable homochiral luminescent MOF was obtained by spontaneous symmetry-breaking crystallization from achiral precursors; it exhibits enantioselective sensing of d/l-Pen.
A new C,N-cyclometalated osmium(ii) arene anticancer scaffold with a handle for functionalization and antioxidative properties
Authors: Ortega Enrique , Yellol Jyoti G. , Rothemund Matthias , Ballester Francisco J. , Rodríguez Venancio , Yellol Gorakh , Janiak Christoph , Schobert Rainer , Ruiz José
Published: September 2018

New osmium(ii) complexes with an uncoordinated ester group for functionalization that are able to decrease the levels of intracellular ROS.
Growth of hierarchical TiO2flower-like microspheres/oriented nanosheet arrays on a titanium mesh for flexible dye-sensitized solar cells
Authors: Xu Yuanmei , Li Xueshi , Xiao Ming , Xiong Xiaoming
Published: September 2018

A triple-layer TiO2(TiO2-TL) structure was synthesized with an over-layer composed of TiO2flower-like microspheres (MSs), a middle layer of nanosheet arrays (NSAs) and an under-layer of compact film (CF) on a titanium (Ti) mesh substrate using a one-step hydrothermal route and used to make a series of flexible dye-sensitized solar cells (DSSCs).
Reaction kinetics and a physical model of the charring layer by depositing Al2O3 at ultra-high temperatures
Authors: Guan Yi-Wen , Li Jiang , Liu Yang , Yan Qi-Long
Published: September 2018

The thermochemical ablation of insulation material caused by slag deposition in solid rocket motors has increasingly attracted researchers’ attention.
The influence of absorbing boundary conditions on the transition path time statistics
Authors: Caraglio Michele , Put Stefanie , Carlon Enrico , Vanderzande Carlo
Published: September 2018

A novel analytical expression, explicitly taking into account absorbing boundaries, exactly describes TPT distributions for particles crossing a parabolic potential.
FLP catalysis: main group hydrogenations of organic unsaturated substrates
Authors: Lam Jolie , Szkop Kevin M. , Mosaferi Eliar , Stephan Douglas W.
Published: September 2018

This article is focused on recent developments in main group mediated hydrogenation chemistry and catalysis using “frustrated Lewis pairs” (FLPs).
The investigation of the electrocatalytic and corrosion behavior of a TiO2–RuO2 anode modified by graphene oxide and reduced graphene oxide nanosheets via a sol–gel method
Authors: Royaei N. , Shahrabi T. , Yaghoubinezhad Y.
Published: September 2018

The participation of GO in the coating structure improved the ClER activity, selectivity, and the electrochemical stability of the electrodes significantly.
Photoluminescence, radioluminescence and thermoluminescence properties of Eu3+doped cadmium tantalate phosphor
Authors: İlhan Mustafa , Keskin İlker Çetin
Published: September 2018

For investigate spectroscopic properties, Eu3+doped columbite type CdTa2O6phosphors were synthesized using the solid state reaction method.
Teaching from the primary inorganic literature: lessons from Richard Andersen
Authors: Stewart Joanne L. , Bentley Anne K. , Johnson Adam R. , Nataro Chip , Reisner Barbara A. , Watson Lori A.
Published: September 2018

Teaching inorganic chemistry using the primary literature motivates students to learn deeply and to engage with the important discoveries of the field.
Simultaneous hetero-atom doping and foreign-thiolate exchange on the Au25(SR)18 nanocluster
Authors: Wei Xiao , Kang Xi , Wang Shuxin , Zhu Manzhou
Published: September 2018

Hetero-atom-Ag doping and foreign-ligand exchange have been synchronously achieved on the Au25(SR)18 template.
Construction of in situ self-assembled FeWO4/g-C3N4 nanosheet heterostructured Z-scheme photocatalysts for enhanced photocatalytic degradation of rhodamine B and tetracycline
Authors: Dadigala Ramakrishna , Bandi RajKumar , Gangapuram Bhagavanth Reddy , Guttena Veerabhadram
Published: September 2018

Constructing a direct Z-scheme photocatalyst of in situ self-assembled FeWO4/g-C3N4 nanosheet composite provides a sustainable pathway for organic pollutant degradation.
Functional evaluation of doxorubicin decorated polymeric liposomal curcumin: a surface tailored therapeutic platform for combination chemotherapy
Authors: Sheena Thankaraj Salammal , Balaji Perumalsamy , Venkatesan Rajiu , Akbarsha Mohammad Abdulkader , Jeganathan K.
Published: September 2018

The present study deals with the hypothesis and design of new platform for the accommodation of curcumin and doxorubicin in surface engineered liposomes for combination chemotherapy.
Electronic effects on reactivity and anticancer activity by half-sandwich N,N-chelated iridium(iii) complexes
Authors: Guo Lihua , Zhang Hairong , Tian Meng , Tian Zhenzhen , Xu Yanjian , Yang Yuliang , Peng Hongwei , Liu Peng , Liu Zhe
Published: September 2018

This work demonstrated how the chemical reactivity and anticancer activity as well as the selectivity of these half-sandwich N,N-chelated iridium(iii) complexes can be controlled and fine-tuned by the modification of the ligand electronic perturbations.
Photochemical strategies for the green synthesis of ultrathin Au nanosheets using photoinduced free radical generation and their catalytic properties
Authors: He Suisui , Hai Jun , Li Tianrong , Liu Sha , Chen Fengjuan , Wang Baodui
Published: September 2018

A photochemical strategy using photoinduced methylene blue radicals for the green synthesis of ultrathin Au nanosheets. The resulting Au nanosheets show highly sensitive recognition of cancer cells and efficient activity and selectivity toward the hydrogenation of α,β-unsaturated aldehydes.
Hybrid plasmonic nanostructures based on controlled integration of MoS2 flakes on metallic nanoholes
Authors: Garoli Denis , Mosconi Dario , Miele Ermanno , Maccaferri Nicolò , Ardini Matteo , Giovannini Giorgia , Dipalo Michele , Agnoli Stefano , De Angelis Francesco
Published: September 2018

A novel method for the preparation of hybrid 2D-material/plasmonic nanostructures paving the way toward hybrid plasmonic nanopores.
Iodine-catalyzed cross-coupling of isocyanides and thiols for the synthesis of S-thiocarbamates
Authors: Pathare Ramdas S. , Patil Vikas , Kaur Harpreet , Maurya Antim K. , Agnihotri Vijai K. , Khan Shahnawaz , Devunuri Nagaraju , Sharon Ashoke , Sawant Devesh M.
Published: September 2018

Synthesis of S-thiocarbamates by employing simple and readily available precursors under mild reaction conditions with good to excellent yields.
Proton-conducting poly(ether sulfone ketone)s containing a high density of pendant sulfonic groups by a convenient and mild post-sulfonation
Authors: Wang Chenyi , Zhou Yuanpeng , Shen Bin , Zhao Xiaoyan , Li Jian , Ren Qiang
Published: September 2018

A class of new poly(ether sulfone ketone)s containing a high density of pendant sulfonic groups on the sulfonated structural units were designed and the resulting membranes exhibited overall good performance at low IEC levels.
A relationship between the V4+/V5+ ratio and the surface dispersion, surface acidity, and redox performance of V2O5–WO3/TiO2 SCR catalysts
Authors: Zhao Xuteng , Yan Yongyi , Mao Lei , Fu Maochen , Zhao Hairui , Sun Lvsheng , Xiao Youhong , Dong Guojun
Published: September 2018

The electron transfer process between vanadium species is omitted and the activated transition state is formed directly.
Coordination properties of N,N′-bis(5-methylsalicylidene)-2-hydroxy-1,3-propanediamine with d- and f-electron ions: crystal structure, stability in solution, spectroscopic and spectroelectrochemical studies
Authors: Kaczmarek Malgorzata T. , Skrobanska Monika , Zabiszak Michal , Wałęsa-Chorab Monika , Kubicki Maciej , Jastrzab Renata
Published: September 2018

The self-assembled metal-promoted synthesis and properties of N,N′-bis(5-methylsalicylidene)-2-hydroxy-1,3-propanediamine (H3L) complexes with d- and f-metal ions are described.
A multistep methodology for calculation of the tensile modulus in polymer/carbon nanotube nanocomposites above the percolation threshold based on the modified rule of mixtures
Authors: Zare Yasser , Rhee Kyong Yop
Published: September 2018

A multistep model is proposed for calculating the tensile modulus values of polymer/carbon nanotube (CNT) nanocomposites (PCNTs) based on the modified rule of mixtures, assuming a percolated network of nanoparticles.
Expression of Ac-PK2 protein from AcMNPV improved the progeny virus productionviaregulation of energy metabolism and protein synthesis
Authors: Wei Lili , Liang Aihua , Fu Yuejun
Published: September 2018

Baculovirus encoded PK2 protein can increase viral fitness through inhibition of the eIF2α family kinases activity.
Electric heated cotton fabrics with durable conductivity and self-cleaning properties
Authors: Lee Suhyun , Park Chung Hee
Published: September 2018

This study was carried out to improve durability and reduce conductivity degradation of polypyrrole-deposited cotton fabrics by introducting a superhydrophobic surface.
Copper antimony sulfide thin films for visible to near infrared photodetector applications
Authors: Vinayakumar V. , Shaji S. , Avellaneda D. , Aguilar-Martínez J. A. , Krishnan B.
Published: September 2018

Copper antimony sulfide (CuSbS2) thin films for visible to near infrared photodetection
Development of an Fe3O4@Cu silicate based sensing platform for the electrochemical sensing of dopamine
Authors: Das Ashok Kumar , Kuchi Rambabu , Van Phuoc Cao , Sohn Youngku , Jeong Jong-Ryul
Published: September 2018

Abnormal levels of dopamine (DA) in body fluids is an indication of serious health issues, hence development of highly sensitive platforms for the precise detection of DA is highly essential.
Nonisothermal decomposition and safety parameters of HNIW/TNT cocrystal
Authors: Zhang Jiao-Qiang , Xu Yun-Long , Jia Qian , Zhang Shi-Jie , Liu Ning , Gao Hong-Xu , Hu Rong-Zu
Published: September 2018

To explore the thermal decomposition behavior and evaluate the thermal safety of the cocrystal HNIW/TNT, its thermal and kinetic behaviors were studied by DSC technique.
Sequential deposition of microdroplets on patterned surfaces
Authors: Kant Pallav , Hazel Andrew L. , Dowling Mark , Thompson Alice B. , Juel Anne
Published: September 2018

We use a combination of experiments and numerical modelling to investigate the influence of physico-chemical-patterned substrates on the spreading of fluid deposited as a partially overlapping sequence of droplets via inkjet printing. We find that both topography and wettability variations are required for robust pixel filling without overspill.
In situ synthesis and in operando NMR studies of a high-performance Ni5P4-nanosheet anode
Authors: Feng Xuyong , Tang Mingxue , O'Neill Sean , Hu Yan-Yan
Published: September 2018

Nickel phosphide (Ni5P4) nanosheets are synthesized using in situ chemical vapor deposition of P on Ni foam, which demonstrate good electrochemical performance including high rate capability. The lithiation mechanism is studied with operando NMR.
Efficient near-infrared (NIR) polymer light-emitting diodes (PLEDs) based on heteroleptic iridium(iii) complexes with post-modification effects of intramolecular hydrogen bonding or BF2-chelation
Authors: Fu Guorui , Zheng Hao , He Yani , Li Wentao , Lü Xingqiang , He Hongshan
Published: September 2018

Two new heteroleptic iridium(iii)-complexes capable of NIR emission are used to fabricate NIR-PLEDs with high efficiency and almost negligible efficiency-roll-off.
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease
Authors: Hu Ning , Wang Jun , Hu Pengfei , Li Zhongmei
Published: September 2018

Renalase gene rs2576178 polymorphism has been demonstrated to be a risk factor of ischemic stroke, essential hypertension, and end-stage renal disease, but the association Renalase with risk of coronary artery disease (CAD) has been less reported. Therefore, we detected Renalase rs2576178 polymorphism in 449 CAD patients and 507 healthy controls using matrix-assisted laser-desorption ionization (MALDI)/time of flight (TOF)-mass spectrometry (MS). It was found that GG genotype or G allele of rs2576178 polymorphism was associated with the risk of CAD. Stratified analysis indicated that Renalase polymorphism significantly increased the risk of CAD in females, smokers, and alcoholics. However, there was no significant association between different genotypes of rs2576178 polymorphism and clinical parameters. In summary, Renalase rs2576178 polymorphism is associated with increased risk of CAD, but this finding should be confirmed by larger studies with more diverse ethnic populations.
Miniaturised triple‐band antenna loaded with complementary concentric closed ring resonators with asymmetric coplanar waveguide‐fed based on epsilon negative transmission line
Authors: Kumar Rajkishor , Singh Reshma , Chaudhary Raghvendra Kumar
Published: September 2018

This study presents an open‐ended triple‐band miniaturised metamaterial (MTM) inspired antenna based on the epsilon negative‐transmission line (ENG‐TL). The zeroth‐order resonance (ZOR) and first‐order resonance (FOR) characteristics are implemented using the ENG‐TL theory. The proposed MTM antenna consists of rectangular and square‐shaped complementary concentric closed ring resonator (CCCRR) in the left and right half of the asymmetric coplanar waveguide (CPW) ground plane, respectively. The CCCRR generates an extra coupling capacitance and inductance, which help for improving the gain at ZOR mode and better impedance matching at higher‐order mode. The resonance characteristic of the antenna is controlled by the shunt elements due to its open‐ended boundary condition. The proposed triple‐band MTM antenna offers measured −10 dB impedance bandwidths of 8.54% (1.12–1.22 GHz), 10.25% (2.22–2.46 GHz) and 35.75% (2.94–4.22 GHz). All these three bands show good impedance matching with appropriate gain and high radiation efficiency and also having an omnidirectional pattern in the xz‐plane and dipolar type pattern in the yz‐plane. The designed antenna shows an overall dimension of 0.11λ0 × 0.11λ0 × 0.006λ0 at ZOR frequency (1.16 GHz).
Challenges and novel solution for wide‐area protection due to renewable sources integration into smart grid: an extensive review
Authors: Eissa M. M.
Published: September 2018

Wide‐area protection and control (WAPAC) is a new technology in the smart grid system. The high penetration of wind farms in power systems is likely to have an adverse impact on the relay operation even if the short‐circuit current in such systems decays rapidly due to crowbar resistance. By including various renewable sources, and information and communication technology components, the power grid will become more complex. Approaches based on wide‐area monitoring system (WAMS) are developed to solve the current challenges of the future of high renewable resources penetration. This study provides the latest main components of the WAMS architecture and the innovation in WAPAC research development using phasor measurement units (PMUs). As the extensive article review in this area is given that show no solution until now for wide‐area protection in case of high wind farm penetration. A new wide‐area protection based on PMUs is deployed. The main concept is based on describing by differential equations the dynamic operation of the transmission lines. In case of faults, the equations become non‐linear and become difficult to be solved. This is the first time to develop such an idea to identify the protected faulted zone and guarantees sustainability for the power flow.
Auxiliary dead‐band controller for the coordination of fast frequency support from multi‐terminal HVDC grids and offshore wind farms
Authors: Jose Khadijat , Joseph Tibin , Liang Jun , Ugalde‐Loo Carlos Ernesto
Published: September 2018

High‐voltage direct‐current (HVDC) grids may provide fast frequency support to ac grids with the aid of supplementary control algorithms and synthetic inertia contribution from offshore wind farms. However, when all converters within the HVDC grid are fitted with these supplementary controllers, undesirable power flows and reduced power transfers may occur during a power imbalance. This is due to simultaneous frequency oscillations on the different ac systems connected to the HVDC grid arising during the support operation. To prevent this adverse effect, an auxiliary dead‐band controller (ADC) is proposed in this study. The ADC modifies the dead‐band set‐point of the fast frequency controllers using measurements of the rate of change of frequency and frequency deviation. A four‐terminal HVDC integrated with an offshore wind farm is modelled to analyse and study the effectiveness of three different supplementary fast frequency control algorithms. Results show that the proposed ADC scheme improves the performance of fast frequency control algorithms. For completeness, a small‐signal stability analysis is carried out to confirm that a stable system operation is maintained.