bluuebunny/crossref_metadata_2025 huggingface dataset:
Figure 1 from The Significance of Comprehensive Metabolic Phenotypes in Cancer Risk: A Japan Multi-Institutional Collaborative Cohort Study
Authors: Watanabe Takeshi , Nguyen Tien Van , Katsuura-Kamano Sakurako , Arisawa Kokichi , Ishizu Masashi , Unohara Taichi , Tanaka Keitaro , Shimanoe Chisato , Nagayoshi Mako , Tamura Takashi , Kubo Yuko , Kato Yasufumi , Oze Isao , Ito Hidemi , Michihata Nobuaki , Nakamura Yohko , Tanoue Shiroh , Koriyama Chihaya , Suzuki Sadao , Nakagawa-Senda Hiroko , Koyama Teruhide , Tomida Satomi , Kuriki Kiyonori , Takashima Naoyuki , Harada Akiko , Wakai Kenji , Matsuo Keitaro
Published: November 2024

Flowcharts of the selection of study participants. A, Study participants for analyses of examination-based metabolic phenotypes. B, Study participants for analyses of questionnaire-based metabolic phenotypes.
Supportive Care for Common Conditions in Small Vulnerable Newborns and Term Infants: The Evidence
Authors: Jiang Li , Lee Him Rachel , Sihota Davneet , Muralidharan Oviya , Dominguez Georgia , Harrison Leila , Vaivada Tyler , Bhutta Zulfiqar A.
Published: November 2024

Introduction: Small vulnerable newborns (SVNs) are at an increased risk of early death and other morbidities. Essential interventions provided to SVN, and other high-risk newborns have been proven critical in improving their outcomes. We aimed to provide an update on the effectiveness and safety of these interventions in low- and middle-income countries (LMICs). Method: Following a comprehensive literature scope, we updated or reanalyzed LMIC-specific evidence for essential SVN care interventions. Results: A total of 113 individual LMIC studies were identified. Most of them were of high risk of bias. Kangaroo mother care significantly reduced SVN’s mortality by discharge. Early erythropoiesis stimulating agent lowered SVN’s risk of receiving blood transfusion. Prophylactic oral or intravenous ibuprofen resulted in a decreased risk of patent ductus arteriosus in SVN. But it did not have a significant effect on mortality and led to a higher risk of gastrointestinal bleeding. No pooled LMIC data were available for universal screening of hyperbilirubinemia in high-risk newborns. Sunlight therapy had no effect in treating hyperbilirubinemia but increased the risk of hyperthermia. Reflective curtains with phototherapy resulted in a greater and faster decline in bilirubin than standard phototherapy in treating hyperbilirubinemia. Early child development interventions were shown to have a favorable effect on cognitive and motor scores in SVN. The evidence for family involvement and family support was limited and uncertain. Conclusion: We present the most updated LMIC evidence for interventions targeting SVN. Despite their effectiveness and safety in improving certain neonatal outcomes, further high-quality trials are required.
Effects of Childhood Trauma and Anxiety on the Hypothalamic-Pituitary-Adrenal Axis in Chronic Subjective Tinnitus with Distress
Authors: Cassiers Laura Lucia Maria , Van Den Eede Filip , Schruers Koen , Gilles Annick , Van Rompaey Vincent , Sabbe Bernard G.C.
Published: November 2024

Introduction: There is some evidence for hypothalamic-pituitary-adrenal (HPA) axis hypofunction in chronic tinnitus, but findings are contradicting possibly due to clinical heterogeneity. This study aimed to assess differential effects of childhood trauma and anxiety on HPA-axis functioning in adults suffering from chronic subjective tinnitus with distress. Methods: Salivary cortisol data were collected in 22 chronic subjective tinnitus sufferers (without major depression) and 29 healthy controls after awakening, at baseline, and after a low-dose (0.5 mg) dexamethasone challenge. A factorial ANCOVA was conducted to compare the main effects of group (tinnitus versus. controls), trauma, and their interaction effect on the cortisol awakening response (CAR). Linear mixed models were fitted for baseline and post-dexamethasone cortisol levels with group, sampling time, trauma, and their interactions as fixed factors and subject as the random effect. The Beck Anxiety Index, Anxiety Sensitivity Index, and Panic Disorder Severity Scale were included to investigate effects of anxiety. Results: A significant interaction between group and trauma (F [1, 47] = 6.9755, p = 0.0112) was found, with the tinnitus group showing lower CARs (M = 5.1808, SD = 0.5821) than the comparison group (M = 5.9974, SD = 0.5251) in traumatized individuals only. No effects were found for baseline or post-dexamethasone cortisol. Anxiety scores had no effects on any of the outcome variables. Conclusion: A differential effect of childhood trauma, but not anxiety, on the HPA-axis function in chronic subjective tinnitus was partly confirmed by the finding of a blunted CAR in tinnitus sufferers reporting early-life adversity.
Cross-Generational Impact of Maternal Exposure to Low Level of PM2.5 on Kidney Health
Authors: Chen Hui , Nguyen Long The , Feng Min , Wang Baoming , Xu Bai , Yarak Rochelle A. , Chan Yik Lung , Viswanathan Seethalakshmi , Komala Muralikrishna Gangadharan , Pollock Carol A. , Oliver Brian G. , Saad Sonia
Published: November 2024

Introduction: Inhaled fine and ultrafine particulate matter may affect organs other than the lung, including the kidney. Recent studies have consistently shown the possibility of air pollution in highly polluted countries to be nephrotoxic. However, in countries like Australia, where air quality generally adheres to or remains below the WHO standards, the subtle yet consequential impacts of chronic exposure to seemingly safe levels of traffic PM2.5, are a subject of increasing significance. However, how such exposures in the peri-pregnancy period affect kidney health in mothers and the offspring is unclear, which formed the aims of this study. Methods: Female Balb/c mice were exposed to PM2.5 (5 μg/day) delivered nasally for 6 weeks prior to mating, during gestation and lactation (PM group). In a subgroup, PM2.5 was switched to saline from mating until offspring were weaned to model mothers moving to areas with clean air. Kidneys were analysed in dams and adult offspring at 13 weeks of age. Results: PM2.5 induced oxidative stress without histological changes in the dam’s kidney. However, male PM offspring displayed in utero underdevelopment, characterised by reduced body weight and kidney-to-body weight at birth compared to control offspring, and lower glomerular numbers, with a marked increase in albuminuria, glomerulosclerosis, inflammation, oxidative stress, and mitochondrial injury. Female PM offspring had delayed postnatal development, lower glomerular numbers, increased glomerulosclerosis, and oxidative stress injury markers. Removal of PM2.5 from conception significantly reduced DNA oxidation and kidney damage in the offspring. Conclusion: There is no safe level of ambient PM2.5 for kidney health when exposed in utero. Maternal PM2.5 exposure equally impacts the kidney health of male and female offspring. Removal of PM2.5 from conception was overall protective to the offspring.
Lu-PRRT used more intensively on advanced GEP and lung NENs: preliminary results on toxicity from a randomized study.
Authors: Grassi Ilaria , Nicolini Silvia , Marini Irene , Matteucci Federica , Ranallo Nicoletta , Di Iorio Valentina , Sarnelli Anna , Foca Flavia , Monti Manuela , Fabbri Lucia , Fantini Lorenzo , Rossi Alice , Paganelli Giovanni , Severi Stefano , Sansovini Maddalena
Published: November 2024

Introduction. Lu-PRRT in NETs is usually delivered with a total cumulative activity (TCA) of 29.6 GBq, divided into 4 cycles and with fixed interval between cycles (IBC) of 8 weeks. Based on prevoius radiobiological studies, reducing IBC could improve efficacy without increasing toxicity. The purpose of this study is to evaluate safety of Lu-PRRT with two different IBC: intensive (every 5 weeks) or standard (every 8-10 weeks).
Methods. From May 2016 to July 2018 patients with advanced and progressive GEP and bronchial NENs were enrolled in a prospective randomized phase II study. Patients with risk factors for toxicity (RF) were planned for a TCA of 18.5 GBq, patients without RF of 27.8 GBq, divided into 5 cycles. Patients were then randomly assigned to be treated according to the intensive or to the standard IBC. Toxicity was monitored according to CTCAE.
Results. 120 patients (61 in the intensive group and 59 in the standard one) were evaluable for overall toxicity. 5 patients (4.1%) had major (G3) hematological toxicity, 2 in the intensive group and 3 in the standard one. Other G3 toxicities related to creatinine, alanine aminotransferase, nausea, and asthenia were observed in the intensive group. 112 patients (54 in the intensive group and 58 in the standard one) performed at least 2 cycles and were also evaluable for cycle-by-cycle toxicity, resulting similar between the two groups.
Conclusion. According to our preliminary results, Lu-PRRT administered intensively could be considered as safe as the standard schedule, when TCA is chosen according to the RF. Further data are needed to confirm these results.
Clinical Predictors of Good/Poor Response to Growth Hormone Treatment in Children with Idiopathic Short Stature
Authors: Dauber Andrew , Phillip Moshe , Ferran Jean-Marc , Kelepouris Nicky , Nedjatian Navid , Olsen Anne Helene , de Lima Jorge Alexander Augusto
Published: November 2024

Introduction: Children with idiopathic short stature (ISS) are known to have varying responses to growth hormone (GH) treatment (GHT).
Methods: We conducted a post hoc analysis to identify clinical characteristics predictive of good and poor response during year 1 of GHT. Data from the NordiNet® IOS (NCT00960128) and the ANSWER Program (NCT01009905) were used. Patients were grouped according to their response to GHT; good, middle, and poor responders had a change in HSDS of >1.0, 0.4–1.0, and <0.4, respectively. Patients were also grouped according to their responsiveness to GH dose. Logistic regression modelling was performed to identify clinical characteristics predictive of response to GHT.
Results: The response analysis set included 207 patients. Patients were 3–11 years old (males) or 3–10 years old (females) at treatment start and were prepubertal throughout year 1 of treatment. Age at treatment start (odds ratio [OR] 0.69, 95% confidence interval [CI] 0.5;0.9, p = 0.0169) and distance from target HSDS (OR 2.05, 95% CI 1.1;3.9, p = 0.0259) were found to be significant independent predictors of being in the good- versus poor-response groups. When patients were grouped according to their responsiveness to GH dose, a positive correlation between GH dose and change in HSDS was observed.
Conclusion: We identified younger age and further distance from target HSDS as clinical predictors of response to GHT in a heterogenous population of children with ISS. Future studies, designed to identify the genetic determinants of response to GHT could further facilitate individualisation of GHT.
Surveillance after endoscopic resection for colorectal tumors: a comprehensive review
Authors: Hotta Kinichi , Matsuda Takahisa , Sano Yasushi , Fujii Takahiro , Saito Yutaka
Published: November 2024

Background:
The goal of surveillance after the endoscopic resection of colorectal tumors is to reduce colorectal cancer (CRC) incidence and mortality. Considering the effective use of the limited endoscopic capacity and the cost of surveillance, it is desirable to develop a surveillance program that is as minimal as possible. In Europe (European Society of Gastrointestinal Endoscopy (ESGE)) and the United States (US) (Multi-Society Task Force (MSTF)), after the results of the National Polyp Study (NPS) were established, guidelines were developed that stratified risk based on initial endoscopy, and surveillance programs for each risk group were proposed. More than 10 years later, the "colonoscopy screening and surveillance guidelines" were developed with the basic principle of "aiming for zero colorectal cancer deaths during surveillance, bowel preservation, and emphasis on patient quality of life" as the guideline principles in Japan.
Summary:
Randomized controlled trials (RCTs) to evaluate the appropriate surveillance intervals after endoscopic resection of colorectal tumors: the NPS, the Nottingham Study, and the Japan Polyp Study (JPS) are summarized. The ESGE, USMSTF, and Japanese guidelines compared low-risk adenoma, high-risk adenoma, advanced neoplasia, piecemeal resection, and serrated lesions by category.
Key Messages:
Surveillance guidelines based on risk stratification were developed in Japan. Guidelines are meaningful only when they are effectively utilized in clinical practice. They must also be revised based on new evidence. It is hoped that new knowledge will be accumulated, especially in Japan, on topics that are currently lacking.
The One Anastomosis Gastric Bypass is a suitable alternative to Roux-en-Y Gastric Bypass in patients with BMI > 50 kg/m2 : a propensity-score matched analysis
Authors: van der Laan Lindsy , Sizoo Dionne , de Heide Loek J.M. , van Beek André P. , Emous Marloes
Published: November 2024

Introduction: Body Mass Index (BMI) ≥ 50 kg/m2 is more challenging for the bariatric surgeon, because of a thicker abdominal wall, more visceral fat, and hepatomegaly by liver steatosis. This study aims to give an overview of 5-year outcomes after OAGB and RYGB in these patients in terms of weight loss, remission of comorbidities, and complications.
Methods: This retrospective single-center cohort study focused on patients with BMI ≥ 50 kg/m2 undergoing OAGB or RYGB between 2015 and 2017 at a non-academic teaching hospital in the Netherlands. A 1:1 propensity-score matched (PSM) comparison was conducted.
Results: In total, 158 patients underwent OAGB and 32 patients RYGB. After performing a 1:1 PSM, we obtained two nearly identical cohorts of 28 patients. Follow-up data after five years was available in 79% of the patients after OAGB and 82% of the patients after RYGB. Both procedures resulted in equal weight loss, remission of comorbidities, and short-term complications. More minor mid-term complications were seen after OAGB (50% versus 18%; p=0.011) due to reflux complaints (50% versus 7%; p<0.001). The number of patients with major mid-term complications did not differ (7% after OAGB versus 14% after RYGB; p=0.388). The only major complication after OAGB was conversion to RYGB due to reflux in 7.1% of the patients. In contrast, major complications following RYGB were more diverse.
Conclusion: Both procedures resulted in similar weight loss, remission of comorbidities, short-term complications, and major mid-term complications; making OAGB a suitable alternative to RYGB for patients with a BMI > 50 kg/m2.
Early Changes in Ocular Biomarkers in Patients with Vogt–Koyanagi–Harada Disease After Pulse Steroid Therapy
Authors: Muto Tetsuya , Kawaguchi Shunsuke , Kusuda Shoichiro , Misu Keita , Sakamoto Masaaki , Machida Shigeki , Imaizumi Shinichiro , Sekiryu Tetsuju
Published: November 2024

Introduction: This study aimed to identify when ocular biomarker changes occur within 1 month and which ocular biomarkers correlate with best-corrected visual acuity (BCVA) at months 1 and 6.
Methods: We evaluated 33 patients with Vogt–Koyanagi–Harada (VKH) disease who received pulse steroid therapy. The central anterior-chamber depth (ACD) and peripheral ACD were evaluated. We also analyzed axial length (AL), BCVA, spherical equivalent (SE), choroidal foveal thickness (CFT), and retinal foveal thickness (RFT). Patients were divided into two groups based on BCVA at months 1 and 6, and correlations with ocular biomarkers were investigated.
Results: RFT and CFT were significantly reduced as early as day 1 (P < 0.001). AL gradually increased, with a significant increase observed at month 1 (P < 0.05). BCVA improved significantly along with SE reduction, with significant changes observed at week 1 (P < 0.05 and P < 0.01, respectively). Anterior chamber biomarkers gradually increased, with significant increases at week 2 for central ACD (P < 0.05) and at month 1 for peripheral ACD (P < 0.05). The better BCVA group at month 1 significantly correlated with thicker RFT (P < 0.01), better BCVA (P < 0.05), shallower central ACD (P < 0.05), and shallower peripheral ACD (P < 0.05) at the initial visit. No correlation was observed between the better BCVA group at month 6 and ocular biomarkers at the initial visit.
Conclusion: Although RFT and CFT changes are the earliest indicators, changes in the anterior-chamber structure appeared to be slow and delayed. Thicker RFT, better BCVA, shallower central ACD, and shallower peripheral ACD at the initial visit correlated with better BCVA at 1 month.
Character education content in science textbook for senior high school students
Authors: Limiansi Kintan , Suranto Suranto , Paidi Paidi , Zuchdi Darmiyati
Published: November 2024

Student textbooks need to contain character education following curriculum objectives. This study aimed to describe the character content in high school science textbooks 10th-grade, analyze the distribution of character content on each topic, and identify similarities in each textbook. The research objectives were answered by inferential content analysis. The books analyzed were two textbooks (one published by the government and one published by a private company). The results showed that both textbooks contained dimensions of the Pancasila student profile presented explicitly and implicitly. The analysis showed that the character content in book 1 was 262 and in book 2 was 463. Book 1 is dominated by critical reasoning (39%) and book 2 is dominated by independence (34%). The distribution of characters on each topic in the two books is different, but both books contain all dimensions of the character profile of Pancasila students. The results of this study are considered for teachers to use various books and learning resources in learning. In addition, the results of this study also provide initial information for future researchers to develop a mechanism for measuring the profile of Pancasila students as a feature of the Independent Curriculum.
The role of authoritative parenting and self-regulation in controlling adolescent aggressiveness
Authors: Abdillah Muhamad Hasan , Zurqoni Zurqoni , Saugi Wildan , Sutoko Ibnu
Published: November 2024

Seeing the many cases of adolescent violence that occurred in Yogyakarta, Indonesia, this study was interested in examining the suitability of authoritative parenting and self-regulation abilities to the level of adolescent aggressiveness. The subjects of this study were 154 class XII students of State Senior High School 1 Sleman. The sample selection was obtained using a stratified random sampling technique. The aim is to obtain student representation from each class. Researchers use the scale as the main tool in obtaining research data on aggressiveness, authoritative parenting and self-regulation. The data was then analyzed using multiple linear regression with the SPSS V26 program. The results of the analysis showed that, simultaneously, authoritative parenting and self-regulation were very significant in suppressing the emergence of aggressiveness in adolescents (F=51.76 and Sig.=.000). Then, both authoritative parenting (Beta=-.37 with Sig.=.000) and self-regulation (Beta=-.35 with Sig.=.000) both were able to have a significant effect on adolescent aggressiveness partially. The conclusion is that adolescents need authoritative parenting at this phase; this is necessary to avoid the emergence or development of aggressiveness in adolescents. Besides that, adolescents must also be equipped with self-regulation skills because most activities are carried out without parental supervision.
Factors that contribute to the sustainability of graduate education in Malaysian research-based universities
Authors: Sariman Mohd Fathi , Tasir Zaidatun , Hashim Noor Hazarina
Published: November 2024

Today, research is a crucial agenda of universities, and graduate education plays an important role in producing research, publications, and innovation. Thus, the quality of graduate education among Malaysian research universities must be enhanced by exploring the factors that contribute to the sustainability of graduate education. This is done systematically based on relevant literatures and experts’ opinions in graduate education. Therefore, the objective of this study is to identify factors that contribute to the sustainability of graduate education among Malaysian research-based universities (RUs). Findings demonstrate that the factors are governance of graduate education, quality of supervision, quality of programs, quality of students, research facilities, research ecosystem, and financial assistance.
Unraveling social and economic problems: what basics of critical thinking skills are needed?
Authors: Sri Utami Wiwik , Kusaeri Kusaeri , Ridho Ali , Yusuf Ahmad , Widodo Bambang Sigit , Prastiyono Hendri , Murtini Sri
Published: November 2024

Equipping knowledge and developing critical thinking skills about social and economic issues to students is important. This study aimed to analyze the ability of prospective students of Islamic State of Madrasah of Insan Cendekia (ISM-IC) to think critically about socioeconomic problems. This research reveals a critical thinking skills gap among prospective students of Madrasah Tsanawiyah/Islamic Junior High School (IJHS) and non-IJHS who participated in the national selection of new students (NSoNS). This study uses a cross-sectional survey approach with standard instruments from the NSoNS ISM-IC. Data was obtained from 1,832 participants in the social sciences group test, consisting of 1,197 people from IJHS and 635 from non-IJHS. Data analysis using R Programming, package ‘ggstatsplot’, and via Microsoft Excel. The result is: i) a gap in social studies scores between IJHS and non-IJHS students of -0.215, with the social studies scores of IJHS students lower than non-IJHS; ii) critical thinking skills are proven to have a very real impact on the occurrence of social studies score gaps, through the inability of students to answer the higher-order thinking skills (HOTs) category questions. This finding indicates the urgency of the education unit to provide nuanced literacy models and learning and HOTs to increase think of critic ability about socioeconomic matter.
Theoretical framework used in parental involvement research: a scoping review
Authors: Solichah Novia , Fardana Nur Ainy , Samian Samian
Published: November 2024

Theoretical perspectives are important in framing a research model of parental involvement. Despite numerous studies examining parental involvement, their findings continue to exhibit inconsistency when viewed through a theoretical lens. A literature review conducted in 2017 examined the theoretical frameworks employed in parental involvement studies conducted between 2007 to 2011. The primary objective of this study is to analyze and offer novel insights into the theoretical perspectives that underpin parental involvement research, adhering to PRISMA guidelines. We conducted an extensive study of literature published between 2012 to 2023 that met the following inclusion criteria: research papers, reports on parental involvement, and reports on theoretical framework. Our study encompassed a systematic search of electronic databases, including Scopus, EBSCO Sciences, Emerald, and Science Direct from July to September 2023 to identify relevant articles. A total of 366 articles were obtained, and 44 articles met the criteria. Four theories frequently utilized in parental involvement research emerged from this study, namely Bronfenbrenner’s Bioecological Theory; Bourdieu, Coleman, and Lareau’s social capital; Social Identity Theory; and Ajzen’s Theory of Planned Behavior. The findings of this research serve as a foundational resource for future research on parental involvement across diverse contextual settings.
Strategies for students’ well-being development: the task-oriented classroom approach
Authors: Wahyuni Esa Nur , Maksum Ali , Aziz Rahmat , Mangestuti Retno
Published: November 2024

Promoting students’ well-being is a vital aspect of education. Creating a conducive classroom learning environment is essential, and task orientation plays a significant role. This paper aims to explore three research objectives related to the influence of the learning environment on student well-being by focusing on creating a task-oriented learning environment. The study employs a quantitative approach with a cross-sectional study design. The study analyzed 1,698 students (676 male and 994 female students) from nine cities in East Java, Indonesia. The results of the simultaneous regression analysis showed that R=.578, R2=.334, and p<.10. The learning environment was found to predict student well-being by 33.4% significantly. At the same time, task orientation was identified as the most dominant factor affecting student well-being. The study’s findings suggest that task orientation could be a solution to enhance student well-being in classroom learning practices. This study suggests the need for teacher development to improve teachers’ professional ability to facilitate learning in the classroom. Future research should consider using central variables, including moderating and intervening variables, to explore the relationship between the learning environment and student well-being.
Disruptive technologies in the university curriculum: use of artificial intelligence
Authors: Reeves Huapaya Enma Sofía , Lazo Chucos Gilmer , Parillo Sosa Efrain , Meza Melva Iparraguirre
Published: November 2024

The so-called “digital era” is synonymous with the transformation of every aspect of human life. This transformation is given by the development of new technologies that modify the way humans communicate and cooperate. Now, it can be said that formal education, compared to other economic sectors, is lagging in the integration of novel technologies in higher education curricula, especially in terms of implementing artificial intelligence (AI). The objective of this research was to conduct a systematic review of the scientific production related to the incorporation of artificial intelligence as a disruptive technology in the university curriculum. It was carried out using a qualitative approach based on a systematic review. The review showed a greater scientific production between 2022 and 2023; it was also evidenced that, as a technology, artificial intelligence has become a disruptive element thanks to its ability to change the role and work performed by teachers, students, and educational institutions. Consequently, the university of the future urgently needs to plan, design, develop, and implement curricula that include artificial intelligence, with the purpose of training better professionals, capable of acting effectively in a technological and productive environment.
Online teaching and learning in higher education institution in the Northern Philippines
Authors: Galanto Ormilla Rashid Ceazar , Ogano Ongan May Grace
Published: November 2024

The study investigates the shift to online education in the Philippines due to the COVID-19 pandemic and its impact on the education system. Understanding this transition is vital as it signifies a significant adaptation affecting both faculty members and students. Conducted at Ifugao State University, Ifugao, Philippines, we employed a convergent parallel design using online surveys and interviews to determine the perceptions of 30 faculty members and 30 students and their experiences regarding pandemic driven online teaching-learning modes. Findings revealed varied satisfaction levels, with students emphasizing time management and comfort with online technologies for successful learning. The study offers insights into the diverse experiences within the online teaching-learning landscape during the pandemic. It highlights the need for faculty training, flexible class schedules, alternative dissemination methods, and institutional support to enhance online teaching-learning strategies.
Management of action research in school: a bibliometric analysis
Authors: Moktar Azlin , Alias Bity Salwana , Rasul Mohamad Sattar
Published: November 2024

This paper employs bibliometric analysis and visualization techniques, including VOS Viewer, to scrutinize trends in managing action research in schools. Utilizing a dataset of 337 articles sourced from Web of Science (WoS) until 2023, the study adheres to PRISMA guidelines to systematically examine authorship patterns, trends, and themes. The analysis reveals a surge in publication rates and a focus on collaborative problem-solving, inclusivity, and global perspectives, with notable contributions from journals like educational action research and authors (such as Wood). Diverse author collaborations and global representation underscore interconnected research themes. Additionally, four distinct clusters—knowledge and leadership, action research and engagement, caring and impact, and empowerment and participation—emerge, encapsulating action research management in schools. However, challenges such as limited discussion platforms, resource constraints, and contextual barriers persist, necessitating enhanced reflective practices and collaborative learning. While bibliometric analysis provides quantitative insights, the study advocates for complementing such approaches with qualitative methods to ensure a comprehensive understanding of action research management in schools, guiding future strategies in educational research.
The Chinese adaptation of turnover intention scale in early childhood pre-service teachers
Authors: Mingxing Shao , Razali Fazilah , Muhamad Mohd Mokhtar , Nasiruddin Nasnoor Juzaily Mohd , Xinchong Sha , Wenling Li
Published: November 2024

The issue of teacher turnover is a global concern, with particularly devastating impacts on early childhood education. Turnover intention (TI) is the most powerful predictor of actual turnover behavior, making early identification of TI crucial for reducing attrition among early childhood preservice teachers (PSTs). Despite this, no measurement tool exists in China to assess the TI of early childhood PSTs. This study aimed to provide a Chinese version of turnover intention scale for student teachers (TIS-ST) and evaluate its psychometric properties for assessing the TI of Chinese early childhood PSTs. A stratified random sampling method was used to select a sample of 537 early childhood PSTs. The psychometric properties of the Chinese version of TIS-ST were assessed through construct validity, measurement invariance, convergent validity, internal consistency reliability, item analysis, and composite reliability analyses. The results demonstrated that the Chinese version of TIS-ST has adequate validity, reliability, and measurement invariance across age. The Chinese version of TIS-ST can facilitate the dynamic identification and understanding of Chinese early childhood PSTs’ TI across different ages and can lead to targeted interventions that address the root causes of attrition among early childhood PSTs. This can ultimately result in more stable and effective early childhood education systems.
A significant systematic review: impact of school head leadership competencies on teacher development
Authors: Ambon Josephine , Alias Bity Salwana , Mansor Azlin Norhaini
Published: November 2024

This article critically examines the impact of school head leadership competencies on teacher continuous professional development (CPD). Utilizing the Preferred reporting items for systematic reviews and metaanalyses (PRISMA) guidelines, a comprehensive search analyze 1,041 English-language publications from 2020 to 2024 taken from the Scopus, Web of Science and Eric databases. These articles collectively underscore the transformative role of leadership in cultivating professional learning community (PLC) enhancing teacher outcomes and spearheading innovative approaches to CPD. The data were collected, reviewed, and underwent a peer-review process before a systematic review. This article synthesizes findings from final articles (n=29) into three main themes: leadership and PLCs, effects of PLCs on teacher outcomes, and innovative approaches to CPD. These themes facilitate not only the CPD of teachers but also contribute to the overall educational environment by fostering collaboration, innovation, and resilience to changes in educational standards and practices. The findings reveal that effective leadership competencies are instrumental in promoting a culture of CPD among teachers. The evidence suggests a compelling link between school head leadership competencies and significant advancements in teacher CPD. This review provides valuable insights for educational policymakers, school administrators and scholars, emphasizing the critical needs for targeted leadership training programs that enhance the efficacy of CPD initiatives.
Desenho Gráfico Popular: catálogo de matrizes xilográficas de Juazeiro do Norte Ceará
Authors:   Universidade Federal do Ceará, Carvalho Gilmar de
Published: November 2024

Este catálogo “ Desenho Gráfico Popular” consolida a série Cadernos do IEB concebida como instrumento de apoio à pesquisa. Registra, observando as normas e facilitando a consulta, a importância do conjunto de matrizes e impressos xilográficos doado por Gilmar de Carvalho. Três centenas de matrizes, outras tantas de folhetos e vinte e dois álbuns de gravura provenientes do nordeste ampliam e diversificam um acervo já referencial para o estudo de nossa literatura de cordel. Este é o catálogo da coleção de gabaritos, panfletos, álbuns e outros materiais impressos a partir de xilogravuras que Gilmar de Carvalho doou à Coleção de Artefatos ditos Populares do IEB-USP (Instituto de Estudos Brasileiros da Universidade de São Paulo). Em uma breve introdução, de Carvalho explica que o uso da xilogravura nos primórdios das artes gráficas ajudou a estimular a produção de publicações populares no Cariri, interior do Ceará, na década de 1940. Esta coleção de materiais provém da área onde ainda existem as artes gráficas tradicionais e onde, de 1986 a 1995, foram produzidas novas versões em resposta às novas exigências. Em nossa atual era dominada pela informática, Gilmar de Carvalho presenciou casos em que uma xilogravura foi utilizada para produzir a arte final de uma fotogravura, ou utilizou uma xilogravura digitalizada.
Intravital Imaging of Disease Mechanisms in a Mouse Model of CCM Skin Lesions—Brief Report
Authors: Orlich Michael M. , Norrén Amanda , Desai Malavika , Holm Annegret , Kozakewich Harry , Schoofs Hans , Mäkinen Taija , Bischoff Joyce , Gaengel Konstantin
Published: November 2024

BACKGROUND:

Cerebral cavernous malformation (CCM) is a disease characterized by vascular malformations that primarily develop in the brain. These malformations are prone to leak, and their rupture or thrombotic closure can cause life-threatening hemorrhages and strokes. Mouse models have been instrumental to study the disease, but most cause premature lethality, precluding the investigation of disease mechanisms through intravital microscopy. Current mouse models also do not recapitulate human CCM skin lesions.

METHODS:

Endothelial-specific deletion of
Ccm3
via systemic tamoxifen application at postnatal day 4 or 5 prolongs survival and induces vascular malformations in the mouse brain and ear skin. CCM skin lesions can also be induced by topical tamoxifen administration directly to the ear. The thin, flat morphology of the ear skin is ideal for intravital microscopy. Dextran dyes and platelet markers allow to study blood flow and blood clot formation in living animals, in real time.

RESULTS:

We report that human CCM skin lesions can be recapitulated in a mouse model and that skin lesions share hallmarks of CCM brain lesions. Intravital imaging reveals that CCM skin lesions are slow-flow malformations prone to thrombus formation.

CONCLUSIONS:

Intravital imaging of CCM skin lesions expands the toolkit of CCM research and allows longitudinal studies of lesion growth.
Limosilactobacillus reuteri ameliorates maternal separation stress in newborn mice and alters subsequent adult behaviour
Authors: Saleh Z.M. , Okeugo B. , Venna V.R. , Blixt F.W. , Quaicoe V.A. , Park E.S. , Giorgberidze S. , Luo M. , Taylor C.M. , Rhoads J.M. , Liu Y.
Published: November 2024

Maternal separation (MS) in mice results in behavioral deficits and gut microbiota dysbiosis that all persist into adulthood. Limosilactobacillus reuteri DSM 17938 modulates gut microbiota, alters systemic metabolites, and facilitates immune regulation. To assess the effect of DSM 17938 on biochemical and behavioural stress-associated changes, newborn mice were exposed to unpredictable MS (MSU) daily from day 7 to day 20 of life, with intragastric administration of DSM 17938 or PBS as control. Body weight, brain levels of cholecystokinin (CCK), glial fibrillary acidic protein (GFAP), corticosterone, and stool microbiota were assessed at day 21. Behaviour tests including Y-maze (YMT), Tail Suspension (TST), and Open Field (OFT) were evaluated in adult mice. MSU resulted in a decrease in early postnatal growth, which improved with DSM 17938. Reduced CCK and increased corticosterone brain levels due to MSU were reversed by DSM 17938. GFAP levels increased with MSU, indicating that the decreased brain CCK was likely secondary to neuronal damage. DSM 17938 treated offspring demonstrated better cognitive function and less anxious behaviour in adult behaviour tests. DSM 17398 corrected stress related gut microbial dysbiosis. In conclusion, early life modulation of gut microbiota by DSM 17938 had beneficial effects on stress-associated physical and biochemical changes caused by MS in neonates and on subsequent adult behaviour.
Califat ottoman et nationalisme arabe vu du Maghreb : les Jeunes Tunisiens prennent la plume
Authors: Moreau Odile , Tedeschi Luca
Published: November 2024

This essay offers a reflection on the political-religious relevance of the Ottoman caliph in the Maghreb, proving to be a factor of Muslim unity, capable of influencing Arab political discourse and public opinion in the early 20th century.

The analysis of the Young Tunisians’ press investigates the nationalist movement’s view of the Ottoman caliph between 1907 and 1918. Focusing on the response to the transformations involving the Ottoman caliph from the Young Turk Revolution in 1908 to the First World War, the article examines Le Tunisien and La Revue du Maghreb, charting the orientation of the Young Tunisians in the face of these changes : the reintroduction of the Ottoman constitution, the deposition of Abdülhamid II, the rise to the throne of Mehmed V, and the rumors for an Arab caliphate.

As a result, the analysis of this case study shows the loyalty to the Ottoman caliph by the Young Tunisians. Finally, this approach allows to read the relationship between Young Tunisians and Young Turks from a different angle. Indeed, if the Tunisian nationalists view the Young Turk Revolution and a constitutionalist and liberal political project as a source of inspiration, and, at the same time, they affirm a strong pan- Islamist sentiment.
Le califat chez les islamistes légalistes : une utopie dépassée ?
Authors: Seniguer Haoues
Published: November 2024

The subject of Islamism is certainly controversial from a scholarly point of view, but it is also and above all regularly caught up in the media maelstrom. This makes it difficult to see things clearly. I defend one central hypothesis : Islamism, which I define as a form of intensified politicisation of Islam, from its Egyptian epicentre onwards, has never had the practical means to realise its original claims, i.e. to systematically realise the Great Narrative (al-riwāya al-kubrā), i.e. [to build the Muslim individual, the Muslim home, the Muslim society, the Muslim state, the Islamic caliphate, up to the point of assuming the leadership of humanity (ustāḏiyyat al-ʿālam)]. However, it is not so much the history of its failures, especially political ones, as the successive setbacks it has had to deal with that fundamentally characterises the legalist tendency in which we are particularly interested. This tendency has more or less explicitly renounced the caliphal utopia and is confronted, like any other political organisation, with the principle of reality.
6. Ties
Authors: Weatherson Brian
Published: November 2024

In this chapter I respond to an objection that theories like mine are committed to implausible closure failures in cases where choosers have very similar options to choose between. I show that the objections rely on the assumption that the chooser aims to maximise expected utility, and this isn’t the right criteria of correctness for decisions in close call situations. It isn’t true that when one is selecting cans off the supermarket shelf, one’s selection is rational iff it is utility maximising. Rather, the rational chooser in such a situation will adopt a strategy that has the best long-run consequences. In this case, the strategy will probably be something like the strategy of picking arbitrarily unless it is clear that one of the choices is defective. Given a theory of rational choice that emphasizes the importance of decision making strategies, rather than the importance of utility maximisation, my preferred epistemological theory gets the right answers. There are two traps to avoid here: closure failure and scepticism. And the focus on strategies, and on choices by ordinary humans not by idealized utility maximisers, lets us avoid both.
9. Evidence
Authors: Weatherson Brian
Published: November 2024

This chapter sets out my interest-relative theory of evidence. I argue that one’s evidence just is what a radical interpreter would say one’s evidence is. But, I go on to argue, in some cases that means we end up playing a kind of coordination game with the radical interpreter. What our evidence is turns on what the right solution to that game. And the solution is interest-relative, but not in the way that knowledge is, nor in the way that rational belief is.
A Note on the Relation between the Cold-V Brightness Temperature Feature and the Above-Anvil Cirrus
Authors: Liang Ziling , Huang Yi
Published: November 2024

Severe convective storms, including supercell thunderstorms, are known to produce distinctive features in satellite imagery, one of which is the cold (enhanced) “V” brightness temperature anomaly pattern. This feature is frequently used by weather forecasters to aid severe weather warnings and is often attributed to the above-anvil cirrus (AAC). However, multiple explanations of the cold-V feature have been proposed, and its relation to AAC continues to be debated. This note aims to clarify their relation, by using the satellite images synthesized from the high-resolution simulation of overshooting convective storms by the Global Environmental Multiscale model combined with the Moderate Spectral Resolution Transmittance radiative transfer model. It is found that most of the AAC are optically too thin to create the cold-V temperature contrast in the brightness temperature field. As the cloud body that contributes the most to satellite-measured radiance locates at the effective emission level, the cloud temperature at this level is found to best explain the brightness temperature features, with a spatial correlation generally exceeding 0.80. Therefore, the temperature inhomogeneity inside the anvil cloud, as opposed to the AAC, is found to be the cause of the cold-V feature. This finding cautions against the notion of a causality relation between the AAC and the cold-V feature and suggests they should be considered as separate evidence in interpreting the satellite images for severe weather forecasts.

Significance Statement

The cold-V feature in infrared satellite imagery is an important indicator used for severe weather warnings. It was believed that this pattern is caused by specific high-altitude clouds known as the above-anvil cirrus. However, our study suggests otherwise. We found that the variations in temperature within the main body of the anvil cloud, not the above-anvil cirrus, are actually responsible for this pattern. This is important because it changes how meteorologists interpret satellite images, potentially leading to more accurate weather forecasts. Our findings encourage further research into understanding cloud temperatures and their impact on weather prediction, which is vital for public safety and preparedness for extreme weather.
Outcomes After Duodenoduodenostomy for Superior Mesenteric Artery Syndrome
Authors: Ang Darwin , Hofmann Alana , Attili Abdelrahman , Sang Whiyie , Soltani Tandis , Richards Winston , Ferber Laurence , Taylor Dana
Published: November 2024

Background

Superior Mesenteric Artery Syndrome (SMAS) is a very rare disease that causes starvation and malnutrition secondary to a mechanical obstruction of the 3rd portion of the duodenum between the superior mesenteric artery and aorta. Long-term outcomes following surgery for SMAS by current methods have a high failure rate of 21%-67%. We report the 3-year outcomes of a novel operation for SMAS described as the duodenoduodenostomy (DD).

Methods

This is a longitudinal case series of 12 patients who underwent the DD operation for SMAS, comparing pre-surgery to post-surgery 3-year outcomes. Weight, Body Metabolic Index (BMI), iron levels, and subjective data were collected to assess restoration of nutrition, correction of malabsorption, and lifestyle. The Wilcoxon signed-rank test was applied to nonparametric matched or dependent samples, with statistical significance set at P < 0.05.

Results

At the end of 3 years, there was a significant increase in median weight and BMI, at 108 lbs vs 123.1 lbs ( P-value 0.0156) and a BMI of 18.57 vs 20.59 ( P-value 0.0161). At 3 months, iron levels normalized after surgery and stayed normal at 45 mcg/dL vs 130 mcg/dL ( P-value = 0.046). After 3 years, 75% of patients gained weight and BMI while 83% were able to maintain their BMI to a normal range.

Conclusion

Our study demonstrates that DD surgery leads to significant increases in weight and BMI, accompanied by improved iron levels. The DD procedure emerges as a promising surgical option in the definitive treatment for SMAS.
Blood low shear rate rheometry: influence of fibrinogen level and hematocrit on slip and migrational effects
Authors: Picart C. , Picart C. , Piau J.M. , Galliard H. , Carpentier P.
Published: November 2024

Red blood cell (RBC) aggregation is of prime importance in vivo and in vitro for low flow rates. It may be estimated by rheometrical measurements at low shear rates, but these are perturbed by slip and migrational effects which have already been highlighted in the past. These effects lead to a torque decay with time so that the true value of the stress at low shear rates may be greatly underestimated. Elevated aggregation being associated with different diseases, pathological blood samples show more pronounced perturbing effects and a strong time dependency in low shear rate rheometry.

To test the dependence of slip and migrational effects on RBC aggregation, and particularly to determine the way in which they depend upon fibrinogen concentration ([Fb]), a home‐made measuring system with roughened internal and external walls (170 $\mu$ m roughness) was used to study low shear rate rheometry for RBC suspensions in PBS buffer containing albumin (at 50 g/l) and fibrinogen at various concentrations. The influences of hematocrit, shear rate, and fibrinogen concentration were investigated. Particular attention was paid to data acquisition at low shear rates ( $10^{-3}$ s $^{-1}$ to $3\times10^{-2}$ s $^{-1}$ ). The combined influence of hematocrit and fibrinogen was investigated by adjusting hematocrit to 44 or 57% and fibrinogen concentration ([Fb]) to 3.0–4.5–6.5 g/l. Microscopic observations of the blood samples at rest were performed. They showed that different structures were formed according to fibrinogen concentration. The rheometrical measurements indicated that torque decay with shearing duration was strongly dependent on fibrinogen concentration and on shear rate at fixed hematocrit. Migrational and slip effects were more pronounced as shear rate decreased, fibrinogen concentration was raised, and hematocrit was lowered. The results have been explained on the basis of the expected microstructure of flowing blood in relation to the microscopic observations at rest.