bluuebunny/crossref_metadata_2025 huggingface dataset:
Sentiment Analysis Using Cuckoo Search for Optimized Feature Selection on Kaggle Tweets
Authors: Kumar Akshi , Jaiswal Arunima , Garg Shikhar , Verma Shobhit , Kumar Siddhant
Published: October 2018

Selecting the optimal set of features to determine sentiment in online textual content is imperative for superior classification results. Optimal feature selection is computationally hard task and fosters the need for devising novel techniques to improve the classifier performance. In this work, the binary adaptation of cuckoo search (nature inspired, meta-heuristic algorithm) known as the Binary Cuckoo Search is proposed for the optimum feature selection for a sentiment analysis of textual online content. The baseline supervised learning techniques such as SVM, etc., have been firstly implemented with the traditional tf-idf model and then with the novel feature optimization model. Benchmark Kaggle dataset, which includes a collection of tweets is considered to report the results. The results are assessed on the basis of performance accuracy. Empirical analysis validates that the proposed implementation of a binary cuckoo search for feature selection optimization in a sentiment analysis task outperforms the elementary supervised algorithms based on the conventional tf-idf score.
Dynamic Backfilling Algorithm to Increase Resource Utilization in Cloud Computing
Authors: Nayak Suvendu Chandan , Parida Sasmita , Tripathy Chitaranjan , Pattnaik Prasant Kumar
Published: October 2018

In this article, the authors propose a novel backfilling-based task scheduling algorithm to schedule deadline-based tasks. The existing backfilling algorithm has some performance issues in comparison with the number of task scheduling in OpenNebula cloud platform. A lease could not be scheduled if it is not sorted with respect to its start time. In backfilling, a lease is selected in First Come First Serve (FCFS) to be backfilled from the queue in which some ideal resources can be found out and allocated to other leases. However, the scheduling performance is not better if there are similar types of leases to backfill. It requires a decision maker to resolve conflicts. The proposed approach schedules the number of tasks without any decision maker. An additional queue and the current time of the system is implemented to improve the scheduling performance. It performs quite satisfactorily in terms of number of a leases scheduling, and resource utilization. The performance result is compared with the existing backfilling algorithms.
A Systems Overview of Commercial Data Centers
Authors: Uzaman Sardar Khaliq , Khan Atta ur Rehman , Shuja Junaid , Maqsood Tahir , Rehman Faisal , Mustafa Saad
Published: October 2018

Data center facilities play a vital role in present and forthcoming information and communication technologies. Internet giants, such as IBM, Microsoft, Google, Yahoo, and Amazon hold large data centers to provide cloud computing services and web hosting applications. Due to rapid growth in data center size and complexity, it is essential to highlight important design aspects and challenges of data centers. This article presents market segmentation of the leading data center operators and discusses the infrastructural considerations, namely energy consumption, power usage effectiveness, cost structure, and system reliability constraints. Moreover, it presents data center network design, classification of the data center servers, recent developments, and future trends of the data center industry. Furthermore, the emerging paradigm of mobile cloud computing is debated with respect to the research issues. Preliminary results for the energy consumption of task scheduling techniques are also provided.
An SVM-Based Ensemble Approach for Intrusion Detection
Authors: Sahu Santosh Kumar , Katiyar Akanksha , Kumari Kanchan Mala , Kumar Govind , Mohapatra Durga Prasad
Published: October 2018

The objective of this article is to develop an intrusion detection model aimed at distinguishing attacks in the network. The aim of building IDS relies on upon preprocessing of intrusion data, choosing most relevant features and in the plan of an efficient learning algorithm that properly groups the normal and malicious examples. In this experiment, the detection model uses an ensemble approach of supervised (SVM) and unsupervised (K-Means) to detect the patterns. This technique first divides the data and forms two clusters as per K-Means and labels the clusters using the Support Vector Machine (SVM). The parameters of K-Means and SVM are tuned and optimized using an intrusion dataset. The SVM provides up to 88%, and K-Means provides up to 83% accuracy individually. However, the ensemble of K-Means and SVM provides more than 99% on three benchmarked datasets in less time. The SVM only classifies three instances of each cluster randomly and labels them as per a majority voting approach. The proposed approach outperforms compared to earlier ensemble approaches on intrusion datasets.
Dealing With Noise and Partial Volume Effects in Alzheimer Disease Brain Tissue Classification by a Fuzzy-Possibilistic Modeling Based on Fuzzy-Genetic Initialization
Authors: Lazli Lilia , Boukadoum Mounir
Published: October 2018

Segmentation is a key step in brain imaging where clustering techniques are widely used, particularly the fuzzy approach which offers active and robust methods against noise and partial volume effect (PVE). To address those imperfections, this article suggests an automatic segmentation of brain tissues for magnetic resonance and functional images of Alzheimer's patients, based on an efficient and robust genetic-fuzzy-possibilistic clustering scheme for the assessment of white matter, gray matter and cerebrospinal fluid volumes. The proposed hybrid clustering process based on: 1) A fuzzy possibilistic c-means algorithm that models the degree of relationship between each voxel and a given tissue. 2) A fuzzy c-means algorithm to initialize the clusters centers, with subsequent optimization by a genetic algorithm. Each stage of the proposed clustering process is validated on real brain data and synthetic images of an Alzheimer's Disease Neuroimaging Initiative (ADNI) phantom. A performance comparison is made with the usual fuzzy techniques. The visual and quantitative results obtained with the proposed approach using various signal-to-noise ratios prove its effectiveness to quantify the tissue volume of images of different modalities types in the presence of noise and PVE. The effectiveness in terms of computational rate is also demonstrated.
Cash on Delivery (COD) as an Alternative Payment Method for E-Commerce Transactions
Authors: Halaweh Mohanad
Published: October 2018

Since the emergence of the World Wide Web, various payment methods for e-commerce transactions have evolved rapidly over time, including credit cards, debit cards, smart cards, e-cash, e-checks, and e-wallets. In recent years, however, the use of cash-on-delivery (COD) has increased. This differs from all other methods of payment in terms of processing, time and place of payment, and parties involved, as well as security and privacy assurance. The aim of this article was to compare COD to other e-payment methods and to consider the implications of COD for both customers and e-vendors. The article also discusses implications for e-commerce practice and highlights areas for future research.
Importance and Impact of Culture and People in Continuous Improvement
Authors: Galli Brian J.
Published: October 2018

The primary objective of this article is to establish the importance and impact of culture and people within organizations to developing continuous improvement. The research encompasses an empirical analysis and chronological literature review to establish viable interactions between people and culture. It will discuss the critical factors in organizational culture and their ramifications on continuous improvement and the somewhat symbiotic relationship between culture and continuous improvement. Moreover, the article will indicate the impact of these relationships on the overall success of the business. The study will then make recommendations on how best organizations can implement sustainable measures to ensure continuous improvement in a highly dynamic and competitive environment.
Empirical Evidence of Organizational Knowledge From a Typological Perspective and Its Linkages With Performance
Authors: Ibidunni Ayodotun Stephen , Moses Chinonye Love , Adegbuyi Omotayo Adeniyi , Oladosun Muyiwa , Olokundun Maxwell
Published: October 2018

Empirical evidence on the role of individuals' and group tacit and explicit knowledge in driving performance, is clearly missing in organisational knowledge literature. To fill this gap, a survey of 504 Managerial, technical and administrative employees of organisations in the Nigerian telecommunications industry form the sample for this study. Based on the multiple regression analysis, the relationship between organisational knowledge and performance was established. The results indicate that managers should focus on group-tacit knowledge, individual-explicit knowledge and individual-tacit knowledge as the most strategic types of organisational knowledge for enhancing performance.
Constructing Identities in Online Encounters
Authors: Vivitsou Marianna
Published: October 2018

This article examines digital storytelling practices of 12-15-year-old students from Finland and Greece. In online settings, students construct virtual selves through video and text-based interactions with peers and, thus, perform identity work using English as the language of communication. This study examines digital storytelling as space of intertextuality where different speakers' utterances resignify the context of learning. The authors apply inductive analysis of interview data and a multimodal approach to digital stories as combinations of semiotic systems in order to link with a dynamic digital literacy. Findings indicate that the students use an impersonal, scientific-like style to explain how a chemical reaction happens in some stories. In others, they place the focus on human relationships with body language and gesture adding a personal style. However, rather than language, it is the way the story is performed and acted out that authenticates student work. This bears implications for both the teaching of English and the design of digital storytelling aiming for web-based peer exchanges.
The Ships of the Northwest Passages - Six Centuries of Technical & Operational Development
Authors: Noble Peter G.
Published: October 2018

While there were certainly marine activities in the approaches to the NW Passages in the pre-Colombian ages, the true search for a passage from the Atlantic to the Pacific, north around Canada was stimulated by the Treat of Tordesillas in 1494, two years after Columbus first "discovered" the Americas. In this treaty, Pope Alexander VI, divided the world beyond Europe between Spain and Portugal, effectively cutting off northern European access to China and the Spice Islands.

Almost immediately the King of England funded exploration of alternative routes and in 1497-98, John Cabot made voyages of discovery to the East Coast of N. America and Greenland. He is credited with the discovery of Newfoundland on one of these voyages.

Cabot was followed by a long line of others who explored for the NW passage and who have left their names in the geography of the north. Frobisher, Davis, Hudson, Baffin, Franklin, M’Clintock, and M’Clure all attempted to find a sea route from the Atlantic to the Pacific.

Further, Drake and Cook centuries apart attempted to find the Pacific end of the Passage without success. The passage was not successfully transited until Amundsen did so over a three-year period completing his transit in 1906, in his ship GJOA, but Larsen in the RCM schooner ST. ROCH made the first true non-stop voyage.

Today the idea of using the NW Passage as a commercial route between the Atlantic and the Pacific basins is unattractive, but increasing ship traffic in these waters is being seen with cruise ships, polar research ships, government resupply ships and ships carrying cargo from mining sites in the north.

This paper will give some history of the ships that have been used over the last six centuries of exploration for and navigation in the NW Passages, and will suggest that some of the hard-won experiences gained are still relevant today.
Development of a New Operational Iceberg Drift Forecast Model for the Grand Banks of Newfoundland
Authors: Turnbull I. D. , King T. , Ralph F.
Published: October 2018

During July 2018, an expedition was carried out offshore northern Newfoundland to central Labrador to profile, track, and forecast the drift of icebergs. One of the central goals of the drift modelling work was to test potential improvements in iceberg drift forecast accuracy up to 24 hours when measured iceberg profiles are used as opposed to estimated iceberg draft and mass. During the expedition, 14 icebergs were profiled using a rapid iceberg profiling system which uses a multibeam for the underwater portion of the iceberg and a LiDAR for the freeboard. The 14 icebergs were tracked on the vessel marine radar, and their drift was forecast using a physical model which time integrates the momentum balance of the forces acting on the iceberg. The iceberg profiles were three-dimensional point clouds which provided a highly accurate representation of the iceberg dimensions and shape, and from which a volume and mass could be readily calculated. The point cloud was projected into a two-dimensional plane from 16 perspective angles and averaged into a single projection of iceberg keel and freeboard against which the currents and winds were forced in the drift model, respectively. Average results for the forecast iceberg position versus observed at 24 hours show approximately a nearly 3 km or 18% improvement when iceberg profiles are incorporated into the drift model as opposed to using estimated iceberg draft, shape, and mass. The drift model will become part of an integrated ice profiling, forecasting, and management system for oil and gas exploration and drilling operations on the Grand Banks offshore Newfoundland.
Trends in Expedition Vessels in Polar Waters
Authors: Salminen Jukka , Vocke Maximilian
Published: October 2018

This paper will study the latest development of the expedition cruise market from lower ice class to latest heavy icebreaker class cruise ships. Expedition cruise industry is growing at the moment quite fast. New designs coming in to the market. Ice classes varies from PC6 to PC2.

The paper will describe current order book for expedition cruise vessels. Aker Arctic developed concept design together with Ponant and Stirling Design International for completely new type of expedition cruise vessel. The Ponant Icebreaker is a heavy PC2 class icebreaking cruise vessel designed to be a world's first truly luxury icebreaking cruise vessel capable to taking passenger to the North Pole. In the paper we will describe what kind of methods were used when selecting the design criteria when operating in extremely harsh environment.

When jumping from PC6 class to PC2 class it is a whole different game, several things must be taking in to account. Environmental impact is also important when designing vessels for fragile Polar environment and selecting the right systems in design phase is important. Passenger safety and comfort is very important. Taking the rules like of the Polar Code and Safe Return to Port rule causes some challenges when designing vessel for high Polar waters. Novel/Additive Information: Designing new type of vessel, which doesn't exist in the market is challenging. New ideas and solutions needs to be evaluated carefully. Selecting the best solutions is an utmost important.
Predicted Ice Images PRIIMA: Methodology and System Evaluation
Authors: Kountouris P. , Rabenstein L. , Cochrane P. , Krumpen T. , Hendricks S.
Published: October 2018

Objectives/Scope

Today's ice information is already outdated the moment it is available, due to sea-ice drift. All Arctic stakeholders are in an urgent need for ice forecasts. Presently there is no high-resolution ice forecast product available on the market. PRIIMA is going to tackle this problem. PRIIMA is being developed in a 6 months kick-start project funded by the European Space Agency (ESA). It started on March 1, 2018.

Methods, Procedures, Process

PRIIMA combines the lower resolution forecast information from operational sea-ice and weather models with an actual satellite image of the ice cover. It performs an image transformation from the recorded satellite image to a predicted image how it might look in 1-3 days. The process involves translation and rotation of ice features as well as scaling of the ice area. The concept is pragmatic in the sense that it establishes a helpful product developed in close collaboration with our test users from the field of cargo shipping, research ice breakers and expedition cruises.

Results, Observations, Conclusions

The prediction of sea-ice situations by image warping of near-real time radar images can be differentiated into scenarios with increasing complexity: Free drifting ice away from the coast with a relatively homogenous wind field can be addressed with a single global transformation operator (G1-method) or determined on the bases of the four corner coordinates of the image (L4C-method).Ice drift close to the coast or in presence of heterogeneous wind fields requires local transformation of subsets of the SAR image. A possible solution is to define a dense grid of control points which will constrain the movement of the inland pixels(LMP method).

The quality of PRIIMA primarily depends on the accuracy of the available wind forecasts. In free drifting sea-ice a 24-hours forecast of the position of individual ice features was within 1 km to the true position.

Novel/Additive Information

PRIIMA delivers ice forecasts with the resolution of a satellite radar image. It enables the operating ice manager a quick assessment of the upcoming ice situation.
Evaluating Risk and Determining Operational Limitations for Ships in Ice
Authors: Bond J. , Hindley R. , Kendrick A. , Kämäräinen J. , Kuulila L.
Published: October 2018

The IMO's International Code for Ships Operating in Polar Waters (Polar Code) entered in to force on 1 January 2017 and provides, for the first time, an international regulatory framework for ships operating in Polar waters. In addition to technical regulations, the Polar Code requires that the Polar Ship Certificate should reference a methodology to assess operational capabilities and limitations in ice: essentially setting operational limitations for the specific ship navigating in Polar waters. The Polar Operational Limit Assessment Risk Indexing System (POLARIS) has been developed as an acceptable methodology for providing guidance on the operational limitations in ice of ships assigned different ice classes and has been directly referenced by the IMO in the Polar Code. The system was developed as a collaborative effort, drawing on operational and regulatory experience from industry and national administrations with experience in setting navigational limitations for ice covered waters. This paper presents the technical background behind the system and supporting information on its practical use both as a voyage planning tool and as real-time guidance on assessing ice regimes ahead of the ship. Validation of the system in the context of other existing regulatory requirements is discussed. The limitations of the system are explored and commentary and proposals are provided on recommended future enhancements.
Nearshore Class Unmanned Surface Vehicles: The Last-Mile Solution for Arctic Littoral-Zone Surveys
Authors: Stewart Helen , Khadjinova Rada , Brumley Kelley , Earl Shannon , Waugh Alex , Thomas Nick , Waugh Bob , Rycroft David
Published: October 2018

Challenges and complications of hydrographic and marine surveys in the last mile between sea and shore are compounded in the Arctic by remoteness, lack of infrastructure facilities, difficult transport, and environmental hazards. Without safe, cost-effective, and technologically fit-for-purpose survey solutions, these last-mile surveys are often neglected or inadequate for their design purposes. These special challenges pose similar difficulties to littoral marine and freshwater surveys in temperate New Zealand. To meet these challenges, experienced surveyors from the New Zealand branch of a global survey company partnered with a New Zealand-based naval architect to design and build a seaworthy class unmanned surface vehicle (USVs) for work in remote and isolated environments. The new nearshore class USV is easy to transport by any commercial means, inexpensive, safe for a two-person crew to operate, and has a customizable payload with large capacity for its size.

The ability to work safely in harsh, remote environments at a reasonable cost make the new nearshore class USV an attractive and cost-effective option for surveying in the Arctic. This paper presents information on this survey solution and discusses advantages to USVs as a survey platform in Arctic environments.
Physical Model Testing for Supporting Ice Force Model Development of DP Vessels in Managed Ice
Authors: Islam Shameem , Wang Jungyong , Brown Jeffrey , Lau Michael , Gash Robert , Millan David , Ocean James Millan
Published: October 2018

The stationkeeping performance prediction of a Dynamic Positioning (DP) vessel greatly depends on the accurate modelling of the ice forces, which in turn depends on managed ice field characteristics (ice concentration, floe thickness, floe size, ice drift speed and direction and inclusion of brash ice and small ice pieces) and the DP system characteristics (DP gain set-ups, control algorithms etc.). Physical model testing is a key tool in understanding and validating the fundamental relationships between the ice environmental parameters and the dynamics of a DP vessel. The National Research Council's Ocean Coastal and River Engineering Research Centre (NRC-OCRE) has conducted two comprehensive series of experiments with one 1/40 scaled and one 1/19 scaled DP vessels, in various realistic managed ice conditions in the ice tank facility in early 2015 and in early 2018, respectively. The primary objective of the model testing programs was to generate a database on managed ice-DP vessel interactions, which was the core to NRC-OCRE's ice force model development and validation activities.

This paper describes the model test planning, preparation of managed ice field, the procedure of the model tests and the methodologies of data analysis for the two model testing programs. In both programs, the physical and mechanical characteristics of the ice field were modelled by controlling ice concentration, ice thickness, floe size, ice strength and the ice drift speed and direction. The ice concentration ranged from a light condition (7/10th) to a very heavy condition (9/10th+) with multiple ice floe sizes ranging between 12.5m to 100m. Multiple ice thicknesses ranging between 0.4m to 2m were used for multiple ice drift speeds (0.2 knots, 0.5 knots, and 1.2 knots) with various moderate to extreme ice encroachment angles. Ice forces were not measured directly but estimated based on the thrusters’ response. In addition, model's 6-DOF motions and accelerations were recorded. Multiple high definition cameras were used to capture the global and local ice-structure interactions both placed in above water and underwater locations. For the 2018 testing program, a new ceiling based video system was introduced that captured the images of the ice basin at multiple overlapping locations, which were processed offline to obtain time sequence full image of the ice basin.

Model testing results for a few representative cases are presented in this article. The DP system used in the testing demonstrated capabilities of the vessel in maintaining station for majority of test cases. The measurements as well as the videos showed complex and highly stochastic ice-ship-boundary wall interactions, particularly for high oblique cases. The data and video captured provided sufficient information for developing novel ice force models for real time applications.
Protection of Subsea Assets Using an Iceberg Protection Structure
Authors: Blundon Andrew , King Tony
Published: October 2018

For oil and gas projects offshore Newfoundland, Canada, subsea structures are generally placed in excavated drill centres which lower the equipment below the natural mudline, protecting the equipment from damage due to iceberg impact. This paper introduces a concept of protecting this equipment by utilizing a concrete structure affixed to the seabed using hammer driven piles.

Iceberg loads have been assessed utilizing a Monte Carlo iceberg contact model and a modified version of the Iceberg Load Software (ILS) developed for regions offshore eastern Canada. The Subsea Iceberg Protection Structure (SIPS) was designed using post-tensioned concrete construction. Preliminary concrete design in addition to pile capacity design is performed utilizing FE analysis. Using a hammer driven piled system, the maximum lateral resistance capacity can be determined in addition to the maximum impact energy absorption.

The internal Subsea Production System (SPS) system has been designed to specifically fit inside the SIPS while maintaining full ROV access for operation, maintenance and future well intervention.

The SIPS was designed as an L1 structure in accordance with ISO 19906. This includes impact from free floating and gouging icebergs. The design load for this impact event was calculated based on energy absorbed through ice crushing. The deformation and global movement of the SIPS was not considered as part of the energy absorption mechanism. The maximum ice crushing design load on the SIPS was determined for four locations on the Grand Banks offshore Eastern Canada.

In addition to the structural design of the SIPS, the piling system was analysed to determine the maximum capacity. The total lateral resistance was determined using a combination of a continuum model and a structural beam model (P-y method). The global movement was less than the maximum allowable deformation of the structure. The structure is therefore considered fit for purpose.

The projected construction and installation cost of this structure shows the potential for reduced costs compared to an excavated drill centre, thereby increasing the feasibility of potential tie-backs.

Using updated knowledge regarding iceberg size and geometry, areal density and ice strength, the analysis and design presented in this paper suggests that it may be more economical to install protection structures rather than dredge excavated drill centres, for marginal fields. In addition, the advancement of the internal SPS system is such that the equipment footprint is compact, requiring limited space within the SIPS.

This paper provides the necessary information to show that installing a structure to protect subsea equipment is technically achievable.
Calcium-Sensing Receptor Autoantibodies in Patients with Autoimmune Polyendocrine Syndrome Type 1: Epitopes, Specificity, Functional Affinity, IgG Subclass, and Effects on Receptor Activity
Authors: Habibullah Mahmoud , Porter Julie A. , Kluger Nicolas , Ranki Annamari , Krohn Kai J. E. , Brandi Maria L. , Brown Edward M. , Weetman Anthony P. , Kemp E. Helen
Published: October 2018

A major manifestation of autoimmune polyendocrine syndrome type 1 (APS1) is hypoparathyroidism, which is suggested to result from aberrant immune responses against the parathyroid glands. The calcium-sensing receptor (CaSR), which plays a pivotal role in maintaining calcium homeostasis by sensing blood calcium levels and regulating release of parathyroid hormone (PTH), is an autoantibody target in APS1. In this study, the aim was to characterize the binding sites, specificity, functional affinity, IgG subclass, and functional effects of CaSR autoantibodies using phage-display technology, ELISA, and bioassays. The results indicated that CaSR autoantibody binding sites were at aa 41–69, 114–126, 171–195, and 260–340 in the extracellular domain of the receptor. Autoantibodies against CaSR epitopes 41–69, 171–195, and 260–340 were exclusively of the IgG1 subclass. Autoantibody responses against CaSR epitope 114–126 were predominantly of the IgG1 with a minority of the IgG3 subclass. Only autoantibodies recognizing CaSR epitopes 114–126 and 171–195 affected receptor activity; inositol-phosphate accumulation was increased significantly in HEK293-CaSR cells, and PTH secretion from PTH-C1 cells was reduced significantly when either were incubated with purified Ab and Ca2+ compared with Ca2+ alone. In conclusion, although the majority of APS1 patients do not have CaSR-stimulating autoantibodies, the hypoparathyroid state in a small minority of patients is the result of functional suppression of the parathyroid glands.
High-Throughput Single-Cell Sequencing of both TCR-β Alleles
Authors: Hosoya Tomonori , Li Hongyang , Ku Chia-Jui , Wu Qingqing , Guan Yuanfang , Engel James Douglas
Published: October 2018

Allelic exclusion is a vital mechanism for the generation of monospecificity to foreign Ags in B and T lymphocytes. In this study, we developed a high-throughput barcoded method to simultaneously analyze the VDJ recombination status of both mouse TCR-β alleles in hundreds of single cells using next-generation sequencing.
Dalla conoscenza biologica alla dimensione esperienziale: le Health Humanities nei Corsi di Laurea in Farmacia / From biological knowledge to the experiential dimension: the Health Humanities within the pharmacy degree courses
Authors: Giardina Simona , Spagnolo Antonio G.
Published: October 2018

La sempre maggiore conoscenza fisiopatologica delle malattie non deve escludere la realtà antropologica del malato dal momento che la medicina ha una finalità terapeutico-assistenziale rivolta proprio al malato. Alla luce di queste considerazioni gli Autori mettono in luce l’importanza delle Medical Humanities anche nei Corsi di Laurea in Farmacia. Il farmacista infatti può essere un legame importante tra medico e paziente; può contribuire all’adesione del malato alla terapia e, dunque, il suo ruolo ha una implicazione etico-antropologica che non può essere sottovalutata. ---------- The Authors present their thoughts on the importance of the Humanities in pharmacy education. They underline how the Humanities contribute not only to the physician’s personal education and his or her clinical training but also to the pharmacist’s personal education. The Humanities have the ability to influence pharmacy student as a whole person: intellectually, emotionally and spiritually. In particular, great literature, art, history, can help professionals to develop and sustain professionalism. As students think about and empathize with the dilemmas that characters in these stories face, they come to better understand their patients, as well as themselves.
CUTANEOUS MANIFESTATIONS OF PRIMARY IMMUNODEFICIENCY DISEASES IN TUNISIAN CHILDREN
Authors: GUIRAT Naouel , Ben Khaled Monia , Ouederni Monia , Ben-Mustapha Imen , Kouki Ridha , Besbes Habib , Barbouche Mohamed Ridha , Mellouli Fethi , Bejaoui Mohamed
Published: October 2018

Abstract. Skin manifestations are frequent among patients with primary immunodeficiency diseases (PIDs). Their prevalence varies according to the type of immunodeficiency. This review provides the reader with an up-to-date summary of the common dermatologic manifestations of PIDs among Tunisian children. We conducted a prospective study on two hundred and ninety children with immune deficiency. Demographic details (including age, sex, and consanguinity) with personal and family history were recorded. Special attention was paid to cutaneous manifestations. Dermatological involvements were grouped according to the etiology of their most prominent sign. Cutaneous manifestations were found in 164 patients (56.5%). They revealed the diagnosis of PIDs in 71 patients (24.5 %). The mean age at presentation was 21 months. Overall the most prominent cutaneous alterations were infectious. They accounted for 106 cases (36.55%). The most prevalent causes of cutaneous infections were bacterial: 93 cases (32.06%). Immuno-allergic skin diseases were among the common findings in our study. These include eczematous dermatitis found in 62 cases (21.38%). Malignancy related PIDs was seen in a boy with Wiskott Aldrich syndrome. He developed Kaposi’s sarcoma at the age of 14 months. Cutaneous changes are common among children with PIDs. In pediatric patients with failure to thrive, chronic refractory systemic manifestations often present in other family members, recurrent cutaneous infections unresponsive to adequate therapy, atypical forms of eczematous dermatitis or unusual features should arouse the suspicion of PIDs and prompt specialized immunologic consultation should be made.
Conversations about measurement and evaluation in impact investing
Authors: Choda Amreen , Teladia Mishkah
Published: October 2018

In response to the enduring social, economic and environmental challenges facing the African continent and its population, development interventions are evolving to embrace new approaches, new partnerships and new means of achieving impact. One such area of heightened innovation and growing activity is impact investing. Impact investing is defined as investments made with the intention of generating both financial return and social or environmental impact. As this momentum in impact investing grows, a complementary area of activity has started to put down roots in Africa – social impact measurement.Genesis Analytics curated and managed the Innovations in Evaluation strand at the recent African Evaluation Association Conference, convened in Uganda in March 2017. This strand was supported by the Rockefeller Foundation and aimed to ignite conversations between impact investment stakeholders and evaluators focused on the African experience with social impact measurement.This article presents themes emerging from the presentations and conversations within the Innovations in Evaluation strand. The article begins with a brief explanation of the rise of impact investing, globally and within Africa, and then goes on to explain the structure of the Innovations in Evaluation strand. This strand included small group discussions and a think tank, which enabled sharing of ideas and experiences between strand participants. The article, therefore, documents the issues emerging during these discussions, including exploration of the concept of impact measurement and how this understanding differs across stakeholders, the currency of impact measurement and emerging practice.The article concludes with presenting what stakeholders and evaluators need to jointly explore to ensure that the African experience is well represented as the impact measurement movement continues to gain momentum globally.
Canon, criterion and circularity: An analysis of the epistemology of canonical theism
Authors: Pratt Morris-Chapman Daniel J.
Published: October 2018

In recent years, William J. Abraham has suggested the creation of a new subdiscipline for examining the epistemology of theology. This article provides an overview of this proposal, highlighting some of the philosophical concepts, such as ‘Aristotelian epistemic fit’ and particularism, that Abraham drew upon when formulating this approach. It then proceeds to an examination of Abraham’s application of these ideas to his preferred theological scheme, canonical theism. Limitations and challenges to Abraham’s position are discussed as well as ways in which weaknesses in his approach might be addressed.
Reflective perspectives on Paul
Authors: Van Aarde Andries G.
Published: October 2018

The article explores various aspects of understanding Paul. It focuses on his use of the expression ‘the gospel of God’ as the ‘good news’ that originates with God (a subjective genitive) and one that is about God (an objective genitive). The article argues that the cross and resurrection constitute the core of Paul’s message and that this message demands a new ethos because of the ‘dying and rising’ in participation with Christ Jesus. For Paul, the messianic era had already commenced. In Paul’s point of view, the heart of the gospel was the announcement of a historical happening, namely the crucifixion of the historical Jesus which is connected to another ‘event’, namely the resurrection of Jesus, which does not qualify as history. For Paul, faith is engagement with the kerygma, and not a kind of loyalty to inherited religious customs. Faith implies undivided loyalty, a personal decision and commitment to believe what is proclaimed.
Electron Spin Resonance (ESR) in detection of aquatic pollution through host-parasite relationship
Authors: Leite Lucas Aparecido Rosa , Kinoshita Angela , Baffa Oswaldo , Azevedo Rodney Kozlowiski de , Abdallah Vanessa Doro
Published: October 2018

Aquatic environmental pollution due to negative human activities remains a major problem. Bioindicators that primarily describe the total concentration of the respective pollutant are very useful tools to aid in the chemical analysis of water in order to obtain knowledge about the levels of pollutants in the environment. This study therefore used Electron Spin Resonance Spectroscopy (ESR) to detect the presence of transition metals (copper, iron and manganese) and possible radicals present in samples of Neoechinorhynchus curemai and its host tissues Prochilodus lineatus, as well in water and sediment of the Batalha River, at the same sample site where fish were collected. Spectral analysis of samples showed the presence of three metals (Cu2+, Fe3+ and Mn2+), in addition to nitric oxide (NO) and humic acid (HA). Quantification of the elements in the samples was possible only for Cu detected in the spectrum of parasites, which was equivalent to 2 ppm. ESR proved to be efficient in the detection of transition-metal ions (Cu2+, Fe3+ and Mn2+), in addition to NO and HA. However, the low concentration values of these compounds in P. lineatus tissues (liver, muscle and intestine) and in the water and sediment samples collected did not allow their quantification, as they were below the limit of detection. It can be concluded that N. curemai had the capacity to accumulate these ions, especially copper.
Drinking water quality in schools of the Santarém region, Amazon, Brazil, and health implications for school children
Authors: Meschede Marina Smidt Celere , Figueiredo Bernardino Ribeiro , Alves Renato Igor da silva , Segura-Muñoz Susana Inés
Published: October 2018

The quality of drinking water and its health implications for school children were examined at schools in the Santarém region, Amazon, Brazil. In this region, the population is fully supplied by groundwater from the voluminous Alter do Chão aquifer. Drinking water samples from three schools in Santarem city and from one school at the rural Mojuí dos Campos town were subjected to microbiological and physicochemical compositional analyses. The health risk of human exposure to chemical compounds through water intake was also evaluated. The results indicated that most water samples were contaminated with total coliform and with E. coli, which could cause serious intestinal disorders for school children. Drinking water was acidic and most of the chemical element concentrations were within Brazilian water potability recommended levels. One exception was the high aluminium content in schools from Santarem served by shallower wells, suggesting that further epidemiological studies are necessary and the monitoring of exposed school children should not be discarded. Elevated nitrate concentrations were also noted in schools from Santarém with shallower wells, indicating lack of sanitation and the importance of periodic monitoring of drinking water to prevent adverse health effects. Quantification of human health risk indicated a hazard in schools served by shallower wells, with aluminium as the main pollutant, followed by nitrate. The results showed that most drinking water quality parameters are in accordance with Brazilian legislation. However, microbiological contamination, water acidity, aluminium and nitrate concentrations must be taken into consideration for local governments in order to prevent related diseases among school children.
On the decategorification of Ozsváth and Szabó's bordered theory for knot Floer homology
Authors: Manion Andrew
Published: October 2018

We relate decategorifications of Ozsváth–Szabó's new bordered theory for knot Floer homology to representations of

\mathcal{U}_q(\mathfrak{gl}(1|1))

. Specifically, we consider two subalgebras

\mathcal C_r(n,\mathcal S)

and

\mathcal C_l(n,\mathcal S)

of Ozsváth–Szabó's algebra

\mathcal B(n,\mathcal S)

, and identify their Grothendieck groups with tensor products of representations

V

and

V^*

of

\mathcal{U}_q(\mathfrak{gl}(1|1))

, where

V

is the vector representation. We identify the decategorifications of Ozsváth–Szabó's

DA

bimodules for tangles with corresponding maps between representations. Finally, when the algebras are given multi-Alexander gradings, we demonstrate a relationship between the decategorification of Ozsváth–Szabó's theory and Viro's quantum relative

\mathcal A^1

of the Reshetikhin–Turaev functor based on

\mathcal{U}_q(\mathfrak{gl}(1|1))

.
Cartridge Cavity
Authors:   Air Brake Tubing and Tube Ftg Committee
Published: October 2018

This SAE Standard covers complete general and dimensional data for the manufacture of, T6061-T6 Aluminum cavities designed to receive Push To Connect threadless fittings known as “cartridges“, for air brake applications. This document is not intended to specify or recommend any style or manufacture of such cartridges but to establish uniform cavity dimensions for interchangeability purposes.
Etruscans and Trojans in Virgil’s Aeneid: Founders of New Civilisational Values of the Roman Empire
Authors: Cergol Jadranka
Published: October 2018

The paper presents fresh reflections on the role played by Etruscans and Trojans in the dramaturgy of Virgil’s Aeneid, seeking to define the civilisational values common to the two peoples – the peoples that were to form the foundations of a nascent Roman Empire both in Augustus’ political programme and in Virgil’s literary concept. Foregrounded is the thesis that Virgil’s conception and structure of the Aeneid juxtapose the historical fate of the Etruscans with the myth of the Trojans: both peoples are the bearers of new civilisational values, which are manifested in military fortitudo, in the monarchic constitution of the empire, and in religious pietas.
Determinación de las curvas IDF en Igueldo-San Sebastián. Comparación de diferentes métodos
Authors: López Rodríguez José Javier , Delgado Oihane , Campo Miguel Ángel
Published: October 2018

Las curvas de intensidad-duración-frecuencia (IDF) son una herramienta fundamental en ingeniería hidrológica. Se ha partido de la serie de precipitación de 88 años registrada cada diez minutos en la estación meteorológica de Igueldo (San Sebastián). Después de aplicar varios test para comprobar la homogeneidad y la no estacionariedad de la serie de precipitación, se determinaron las curvas IDF mediante un análisis de frecuencia con el programa Hydrognomon. Dichas curvas se compararon con las obtenidas a partir de la serie simulada con el modelo estocástico de Barlett-Lewis Modificado (MBL) y con las estimadas mediante la ecuación de Témez. El objetivo de este trabajo es la evaluación de estas dos últimas metodologías. Las curvas y los yetogramas generados con la expresión de Témez presentaron un buen ajuste a partir de periodos de retorno, T, mayores a 20 años. No fueron tan buenos los obtenidos a partir de la serie simulada con MBL.
Influencia del nivel inicial en la definición de resguardos estacionales en presas
Authors: Gabriel-Martin Ivan , Sordo-Ward Alvaro , Garrote Luis
Published: October 2018

El estudio presenta una metodología de carácter estocástico para la definición de Normas de Explotación optimizando tanto la explotación ordinaria como la seguridad hidrológica de la presa. Además, la metodología permite tener en cuenta la variabilidad del nivel inicial en el embalse en el momento de avenida. El caso de estudio es una presa bóveda clasificada como tipo A en función del riesgo potencial cuyo principal uso es el regadío. En el caso de estudio, se ha determinado un conjunto de resguardos que, cumpliendo la normativa relativa a niveles máximos en el embalse, maximizan la demanda máxima atendible para una garantía volumétrica del 90%. Se ha observado que al tener en cuenta la variabilidad del nivel inicial en el momento de avenida, la presa del caso de estudio no necesita resguardos para cumplir la normativa, mientras que si se supone embalse lleno el volumen de resguardo es de 70 hm3 en una de las estaciones. La metodología presentada puede ser de utilidad para el análisis y priorización de inversiones en seguridad hidrológica de presas existentes.
Les écoquartiers: dernier linéament contrarié de la grande histoire de l’Utopie?
Authors: Violeau Jean-Louis
Published: October 2018

Utopia today draws a critical horizon rather than a promising future. Too often, this promise may have been a tool to plea for patience and justify the immediate sacrifices in the name of a nebulous future. For a long time the construction of the city was an integral part of a larger project to build a new society. But under the contemporary aegis of "sustainable development", the new sentence is yet to take an original form. In eco-neighbourhoods, the plot is still despotic, and it only re-emerges from its box under the spectre of heliotropism, under the aegis of thermal performance and of neighbourhood plans dictated by the housing orientation. As for the "smart city" -a discovery of the field of marketing-, it will always draw a smile in our faces. Whereas sustainable development emerged in the 2000s as a soft and unanimous slogan, degrowth took over in the 2010s, turning into a hard cleaving slogan. But how to envision the "project" within this horizon without adopting a regressive posture?
Traducción, validación y adaptación transcultural del schoolagers´ coping strategies inventory para escolares colombianos
Authors: Briñez Ariza Karol Johanna , Castillo Clara Virginia Caro , Prado Marta Lenise Do
Published: October 2018

Objetivo: Realizar a tradução, validação e adaptação transcultural do Schoolagers' Coping Strategies Inventory (Inventário de Estratégias de Enfrentamento de Escolares) (SCSI) com estudantes colombianos. Métodos: Estudo metodológico realizado entre 2015 a 2016 com alunos de 8 a 15 anos de idade, de instituições de ensino públicas e privadas, em Ibagué, Colômbia. Utilizou-se a ficha de caracterização e o SCSI. A validação transcultural foi organizada em oito etapas: tradução oficial para o espanhol; tradução do original para o inglês; tradução reversa; versão consensual; validade facial e adaptação à língua pelos estudantes; validade facial e de conteúdo por especialistas; versão final; teste piloto e confiabilidade. Resultados: A versão original em inglês foi adaptada para o idioma espanhol colombiano, com a intervenção de estudantes, de estratos socioeconômicos altos e baixos, em grupos focais e teste piloto, utilizando suas expressões verbais e modificando 4 itens; e com a colaboração de especialistas em pesquisa metodológica e em coping, também modificando 4 itens, com confiabilidade de 0,80. Conclusão: O SCSI foi traduzido, validado e adaptado transculturalmente para a população colombiana. A versão obtida foi o SCSI-VCONF, o qual mostrou-se compreensível para a população-alvo e válida e confiável para pesquisas com escolares para determinar a frequência de uso e efetividade de estratégias de enfrentamento.