bluuebunny/crossref_metadata_2025 huggingface dataset:
Case Report: Acute Respiratory Distress Syndrome With Meningoencephalitis With A Known Case of H.I.V.
Authors: Roshani Patel  , Shakib H. Sheikh  , Indu Alwadkar  , Priyanka Meshram  , Ranjana Sharma  , Roshan Umate
Published: November 2022

Introduction: Meningoencephalitis and meningitis have a broad differential diagnosis: Infections caused by entero-viruses, human HPV types 1-4, 5, and 6, paramyxovirus (mumps), measles virus, and adenoviruses are among the causes of T.B. Clinical signs of primary H.I.V. infection cause hyperthermia, exhaustion, cold and cough, migraine, nasal cavity inflammation, widespread allergy, lymphadenopathy, and digestive issues. 2 Up to 17% of individuals get aseptic meningitis, meningoencephalitis, and encephalitis, which could be related to a quicker course of treatment for the disease and complication. After the onset of the initial H.I.V. infection symptoms and all other symptoms have subsided, neurological symptoms may develop or show up to 3 months later. Respiratory failure is a reasonably typical presentation to the I.C.U. in HIV-infected individuals. Since the meningoencephalitis epidemic, the overall incidence of Pneumocystis jiroveci as a cause of respiratory failure has decreased. There is evidence that continuing or initiating HAART in critically sick H.I.V. patients is helpful and should be addressed following a multidisciplinary discussion. Conclusion: One instance of meningoencephalitis and two cases of meningitis caused by primary H.I.V. infection is discussed. Patients with H.I.V. frequently enter the I.C.U. Due to respiratory insufficiency. Since the AIDS crisis, Pneumocystis jirovecii has generally become less common as a cause of respiratory failure. There is proof that starting or maintaining HAART is suitable for H.I.V. patients who are critically sick, so this should be taken into consideration following a multidisciplinary discussion. A literature analysis was carried out because critical care professionals have significant moral and practical repercussions when selecting whether to assist HIV-infected patients in the I.C.U.
The Nursing Management of the Snyder Robinson Syndrome
Authors: Samyak Pazare  , Shakib H. Sheikh  , Indu Alwadkar  , Mayuri Yelekar  , Ranjana Sharma  , Pratiksha Munjewar
Published: November 2022

Snyder-Robinson syndrome
Case report on Management and outcome of Prostatomegaly with Bilateral Hydronephrosis with diabetic Mellitus
Authors: Shruti Moon  , Aparna Kawale  , Dharti Meshram  , Priyanka Meshram  , Pratiksha Munjewar  , Aniket Pathade
Published: November 2022

Background: - Prostamegaly is a term that refers to prostate gland enlargement due to a 30cc(ml), Benign prostatic hyperplasia (BPH), after recognizing an enlargement prostate gland, becomes more frequent in men as they become grown up. An enlarged prostate gland may cause briny symptoms such as preventing urine from leaving the bladder. They reason bladder, urethral, and kidney problems. The blockage of urine before the renal pelvis causes hydronephrosis. The obstruction causes dilatation of the nephron tubules and flattering of the tube lining within the kidneys resulting in renal calyces enlargement. Acute or chronic hydronephrosis can occur. Presentation of case: A 70- year male came to the hospital with chief complaints of repeated hypoglycemic attacks with a gasping state. He was intubated in casualty in an unconscious state. Physical examination and investigation were done and the doctor diagnose a case of Prostatomegaly with Bilateral Hydronephrosis with diabetes mellitus. After physical examination and investigation were done and doctor diagnose a case of Prostamegaly with Bilateral Hydronephrosis with diabetes mellitus. Medical interventions provide to the patient such as Inj. Citri 1mg given in twice a day to reduce the infection, Inj. Pan 40 mg given twice a day, Inj. Emest 4 mg intravenously given in three times a day, Tab. Urimax was given in once a day, Tab. Amlo 5 mg given in once a day, Tab. Mucomix 600 is given twice a day. Tab. Neurobiol forte gave in stat. after receiving medical management patient's outcome was good. Conclusion: - Early diagnosis and treatment are very important to secure the life of a patient and prevent further complications.
A CASE REPORT ON RIGHT SIDE CORTICO- CAVERNOUS FISTULA
Authors: Sukanchi Pohekar  , Pallavi Dhole  , Ruchira Ankar  , Roshan Umate
Published: November 2022

INTRODUCTION: The cortico-cavernous fistula is uncommon and uncommonly uncommon. A cortico-cavernous fistula is characterized by an abnormal vascular connection between the internal or external carotid arteries and the venous channels of the cavernous sinus. If left untreated, it might cause additional complications such as intracerebral hematoma, subarachnoid hemorrhage, epistaxis, and otorrhagia. Secondary cortico-cavernous fistula cause glaucoma.CASE PRESENTATION: The interventional radiology unit of the tertiary care hospital in Wardha received an admission of a 22-year-old man. He arrived complaining of a 15-day-old facial and nasal bone injury, which had left him with suitable eye redness, pain, and edema in addition to a headache. Additionally, he was traumatized by a vehicle accident. There is no history of hematemesis, nausea, or vomiting. There is no history of a cold, a cough, or a concussion. Such illnesses as diabetes mellitus, hypertension, T.B., and asthma were absent. There was a physical examination. Save for the eye, other physical characteristics are typical. Redness and swelling are seen in the right eye. Above the conjunctiva, is a thick, red blood vessel. The S1 and S2 noises were usual. On the abdomen, there are no scars or enlargements.THERAPEUTIC MANAGEMENT: The patient was admitted for interventional radiology therapy of a cortico-cavernous fistula. Vital readings for the patient, like blood pressure, were 120/80. The measurements were 37 °C temperature, 75 b/m pulse, and 15 b/m respiration rate. After the patient's accident-related medical history was obtained, an evaluation of the patient's physical condition, blood work, a C.T. Scan, an MRI, an X-ray, and an E.C.G was evaluated. The patient had received antibiotics, antiplatelet medications, antiemetics, antacids, and analgesics. The patient had received antibiotics, antiplatelet drugs, antiemetics, antacids, and painkillers. The patient has been advised to undergo cortico-cavernous fistula embolization surgery.
Case report on: - A case report on management and outcomes of Bart Syndrome
Authors: Vaibhav Raut  , Seema Kolhe  , Pratiksha Munjewar  , Roshan Umate
Published: November 2022

A limited number of (neutropenia), a weaker and enlarged heart, skeletal myopathy, recurrent infections, and short height are all features of the rare illness known as Bart syndrome. Bart syndrome nearly always affects men. Dilated cardiomyopathy frequently manifests at birth or during the first few months of life in males with Bart syndrome. The heart muscle weakens and loses its capacity to pump blood with time. Elastic fibres may replace muscle fibres in some parts of the heart muscle in people with Bart syndrome, which adds to cardiomyopathy. Endocardial fibroelastosis is the name of the disorder that causes the muscle to thicken and affects how well it pumps blood. Heart failure can result from heart issues in persons with Bart syndrome. Rarely the cardiomyopathy improves with time, and those affected eventually show no signs of cardiac illness. Main symptoms and significant findings: A 5 months old baby boy was admitted to the hospital. Wardha on dated Jun 23 2022. Chief complaints of enlarged heart, low blood cell count, weakness of muscles, and fatigue.Additionally, there can be increased levels of chemicals like 3-methyglutaconic acid and 2-ethyl hydracrylic acid in the urine or blood. The primary diagnosis, therapeutic interventions, and outcomes: The patient was treated conservatively without surgery after the doctor discovered Bart syndrome following a physical examination and investigation. When the patient was brought to our hospital, the wounds had crusts and dead tissue but showed no evidence of infection. We removed crusts and dead tissue using mechanical and hydrodebridement techniques with sterile saline. Next, we administered an antimicrobial ointment to prevent disease and encourage wound contraction. A gauze bandage infused with petrolatum was also used to keep wounds moisturized. Antibiotics weren't administered intravenously or orally. The skin lesions were entirely epithelialized and healed after three months, leaving just a pigmented scar in their place. He underwent all treatments, and the results were positive. Her complaints have slightly decreased. Conclusion: We describe a case where Bart syndrome symptoms were found following our patient's enlarged heart, low blood cell count, muscle weakness, and exhaustion. These symptoms exactly matched those listed as official Bart syndrome symptoms. An uncommon congenital skin condition known as Bart syndrome has a distinctive clinical appearance. It's crucial to search for related oddities. The prognosis for the syndrome is generally good, however, the best results can be achieved by treating it as soon as feasible.
Case report on:- A case report on management and outcomes of vesicle calculi with right ureteric calculi
Authors: Vishal Ramteke  , Seema Kolhe  , Pratiksha Munjewar  , Roshan Umate
Published: November 2022

Stone diseases that affect the urinary system include urinary tract stones. One common disorder of the urinary system is stones in the urinary tract. According to where they occur, the four different types of stones are categorized as well as urethra, bladder, kidney, and ureteral stones. The patient healed fast and was released after receiving a series of systematic and successful treatments, including completing the one-stage operation. Whole urinary calculi can be eliminated after a single therapy, and urolithiasis persisting over the entire term is uncommon. After seven days of treatment, the clinical improvement response was outstanding and considerable. After receiving Unani therapy for a month without surgical intervention, a U.S.G. finding was suggestive of the absence of any calculi in the left kidney and ureter. The formulations prevented urinary supersaturation of lithogenic chemicals and proved safe and efficient. Clinical findings: For the past four years, problems included abdomen ache, frequency, hesitation, and a burning sensation while passing pee. There was a history of blood in the urine on several occasions. He then proceeded to Rural hospital Wardha. Diagnostic evaluation: After being admitted, the patient had an abdominal computed tomography (C.T.) scan.The findings revealed right ureteric calculi and vesicle calculi. The results of a routine urinalysis indicate that the blood's WBC count is 4,578/L and that the creatinine (Cr) level is 140 mmol/L. Therapeutic intervention: Catheterization and bilateral nephrostomy were our first treatments, which resulted in grey pyuria. Simultaneously, piperacillin-tazobactam was widely utilized as an anti-inflammatory agent. Outcome: The patient's health has improved once all interventions have been completed. The patient's lower abdomen pain and burning when urinating have subsided, and she is now stable. Conclusion: Rarely occurs urolithiasis with an entire challenging course.
Case Report on Neglected bilateral feet Congenital Talipes Equinovarus with Callosities on the lateral aspect
Authors: Rohini kakde  , Samrudhhi Gujar  , Ashish Bhagat
Published: November 2022

Background: Congenital deformity of both feet is also called clubfoot. A common congenital orthopedic condition characterized by an excessively turned in the foot (equinovarus) and high medial longitudinal arch (cavus). If neglected the deformity can result in long‐term disability and pain. Interventions can be conservative such as splinting or stretching or surgical. Talipes equinovarus is one of the more common congenital abnormalities affecting the lower limb and can be challenging to manage. There is evidence for a genetic contribution to congenital talipes equinovarus etiology. Case Presentation: A 7 years old Male child came to the Pediatric department with a chief complaint of deformity of both feet since birth. No Interventions were done during the first month of the baby. And that serial casting was done on both feet for 1 year, yet no correction was observed. After 1 year of age posterior soft tissue release of the right leg. After every 10 days, serial casting was done and yet no correction was observed. Now came to the Pediatric department for further management. On arrival, a physical examination of the foot was carried out which shows swelling over the right leg along with tenderness. The Contrast Enhanced Computed Tomography was done later he was treated with antibiotics, analgesics, and antacids. Conclusion: It is a congenital deformity foot. The congenital deformity of the foot may occur lateral and bilateral. The congenital deformity of the bilateral foot is common in children. The bilateral deformity of the foot affects 80% or more. The most significant contributing component to its cause appears to be heredity. The prevalence of congenital talipes is uncommon and roughly equal in both sexes.
To Assess the Effectiveness of Information Booklet About Perimenopausal Symptoms and Coping Strategies Adopted By Class Iv Workers In AVBRH
Authors: Abhilash Satone  , Abhishek Ade  , Namrata Agashe  , Amisha Chavan  , Archana Teltumbde
Published: November 2022

Background: The researcher observed a knowledge gap among the female class IV employees of Acharya Vinoba Bhave Rural Hospital, Sawangi (Meghe) Wardha, regarding perimenopausal symptoms and coping mechanisms. Many of them stated how unpleasant it was to carry out regular tasks while experiencing menopausal symptoms. The researchers came to the conclusion that in order to assist these class IV employees in their everyday lives, it is important for them to understand perimenopausal symptoms and the tactics that may be used by them to manage these symptoms.Method: The plan was implemented using an interventional method. Data were collected using a non-probability convenience sampling technique. 46 ladies at Sawangi (M) Wardha's AVBRH have been selected to take part in the study.Result: 2.17 percent of class IV workers had poor levels of knowledge, while 97.83 percent had average levels, according to the knowledge table for women. Scores on the preliminary knowledge exam varied from four to ten, with four representing the lowest score and ten representing the highest. The average pretest knowledge scores were 8.13, 1.27 and 40.65, 6.37, respectively, while the average knowledge score percentage was 8.13, 1.27.Conclusion: The research revealed that most women over 45 have an average degree of awareness (47%) of female perimenopausal syndrome. Thus, study hypothesis is accepted. This shows that women who are 45 years of age and older are well-informed about female perimenopausal syndrome.
Assess the Effectiveness Of Information Booklet Regarding Recycle Of Plastic Waste Among Community People
Authors: Shaila Bagwe  , Rajnandini Bawankar  , Prajwal Bhagat  , Avantika Bhoyar  , Shalini Moon
Published: November 2022

INTRODUCTION: Plastic is widely utilized all around the world. India is one of the top 15 polluters of plastic in the world, producing over 26,000 tonnes of plastic waste daily. On August 20, the LokSabha forbade the use of single-use plastic water bottles and other items. The government-run railroads will adhere to the same rules at all stations and aboard trains. According to a 2018 analysis by the Energy and Resource Institute in Delhi (TERI), which used information from India's federal pollution control agency, the country's annual output of solid garbage is made up 8% by plastic, the most of which is produced in Delhi, Kolkata, and Ahmedabad (CPCB) A total of 60 community members in Paloti Sawangi (M), Wardha, participated in this study.METHOD: For this study the Non- Probability quantitative sampling technique had been used.RESULT: One group per pre-test and post-test in the study's design. The knowledge of effective recycling and trash disposal practices for plastic was assessed. The study's findings showed that the average post-test score was 20.46, greater than the table value of 0.0001 S,p0.05 level, with a calculated pair-paired "t" value of 43.25. Additionally, the respondent's knowledge exceeded the mean pre-test knowledge score, which was 7.05 overall with a standard deviation of 2.25.CONCLUSION: Due to this, the information brochure on the risks of using plastic and correct disposal was successful and statistically significant. The study discovered no association between any specific demographic characteristic and the post-test knowledge score at a significance level of 0.05. The data analysis included both descriptive and inferential statistical methods.
TO ASSESS THE MATERNAL AND NEONATAL OUTCOME OF OLIGOHYDRAMNIOS AMONG THE ANC MOTHERS
Authors: Akash.R. Chaudhari  , Prachi S. Chaware  , Pallavi V. Chonde  , Debarati P. Bera  , Pradhnya Sakle
Published: November 2022

Background : Oligohydramnios is a condition in which the amniotic fluid volume (AFV) is lower than usual for the gestational age. The volume of the amniotic fluid changes throughout pregnancy and increases linearly up to 34–36 weeks, which results in a reduced post-term gestation. This pattern facilitates fundal height measurements and pregnancy ultrasound analysis for the clinical evaluation of AFV. After the sonography has thoroughly scanned the belly, the largest vertical pockets of amniotic fluid can be seen that are free of the unborn child's body components or umbilical cord. Both single-fetal and multifetal gestations are considered to have oligohydramnios if the pocket is smaller than 2 cm. Objective : To assess the maternal and neonatal outcome of oligohydramnios among the ANC mothers. To associate the maternal and neonatal outcome of oligohydramnios among the ANC mothers with selected demographic variables. Research Design : Research Approach descriptive Research Approach. Setting of the study: the study was conducted at AVBR Hospital sawangi Meghe Wardha Population : ANC mothers. Sampling technique : simple random sampling .Sample size : 25. CONCLUSION : In order to analyse the maternal and newborn outcome of oligohydramnios among ANC moms, the researcher used a descriptive research design, which is examined in the section that follows the thorough analysis in this thesis. Under the headings of sepsis, perineal laceration, postpartum haemorrhage, premature membrane rupture, placental insufficiency, twin to twin transfusion syndrome, and cardiomyopathy, the mother outcome is broken down. Additionally, the neonatal outcome is broken down into the categories of low birth weight, APGAR scores at 1 and 5 minutes, reflexes, congenital anomalies, admission to the NICU, intrauterine growth restriction, birth asphyxia, foetal distress, delayed lung maturation, preterm birth, and stillbirth.The demographic characteristics did not significantly affect the maternal or neonatal outcome of oligohydramnios. As a result of the assessment and low levels of amniotic fluid found in this study, it is advised that all women increase their ANC visits in order to lower the risk of oligohydramnios in ANC mothers.
Assess the Effectiveness of Video Assisted Teaching on Knowledge Regarding Child Birth Preparation Among Primi Gravida Mother in hospital
Authors: Ishwari Deotale  , Abhishek Deshmukh  , Lakisha Dhoble  , Sayali Deshmukh  , Bali Thool
Published: November 2022

Background: The researcher noticed that pregnant mother in the prenatal OPDs of the hospitals lacked knowledge about labor preparation throughout her clinical experience. In the third trimester, many of them were unprepared for their life' most significant event. Many new mothers described their labour and delivery as being "awful."The researcher concluded that in order for these mothers to have a satisfying and healthy birthing experience, they needed to get information on labor preparation.Method: This interventional trial was carried out in August 2020 at a hospital in the Maharashtra (India) city of Wardha. The population of primigravida moms was chosen for this study using a non-probability convenience sampling approach.Result: In this study 30 sample taken for the research the research design taken for that pre-experimental and the study was quantitative research study. The research conducted in hospital H0 show that primigravida mother knowledge level in pre-test 16.67% which is poor score, 83.33% which is The H0 was acceptable because the average score had a minimum of 3 and a maximum of 10. In the post-test 33.33% the score was very good, 66.67% score was excellent The H1 was approved since the post-test minimum and maximum scores were 17 and 25, respectively. It is concluded that there is H0 and H1 is accepted. It helpful in improve the knowledge level of primigravida mother.Conclusion: We draw the conclusion from this study that there is a lack of understanding among primigravida mothers regarding childbirth preparation, so we launched the video aided programme to raise knowledge and awareness of the subject.
EVALUATE THE EFFECTIVENESS OF PLANNED TEACHING PROGRAMME ON KNOWLEDGE REGARDING BONE DENSITY INVESTIGATION AND ITS IMPORTANCE IN SELECTED COMMUNITY AREA
Authors: Rohini Kakde  , Prachi Kamble  , Nishant Kate  , Bhavesh Kathwate  , Darshana Wankhede
Published: November 2022

The cross-sectional research on premenopausal women
To Assess the Effectiveness Of Self-Instructional Module On Knowledge Regarding Good Sleep Practice Among Antenatal Mothers
Authors: Dhananjay Vihirkar  , Sahil Vihirkar  , Mayur Waghaye  , Apeksha Wakade  , Sheetal Sakharkar
Published: November 2022

BACKGROUND OF THE STUDY: - Sleeping is a physiological habit that occurs in all animal species. A third of a person's lifecycle is made up of it. Although the specific features of sleep are unspecified, they appear to be vital to living because chronic sleep deprivation causes severe physical impairment, cognitive decline, and death. Sleep disturbances have clinical significance because they are symptoms of almost all mental illnesses. Different people need various amounts of sleep. The recommended daily allowance of night's sleep is around 7 and 9 hours. While some people need about 12 hours of sleep each night, others can function well on less than 6 hours. Good sleeping habits and getting enough sleep are crucial for enhancing cognitive function, preventing health issues, and avoiding psychiatric disorders. In Iran (87%), China (87%), and the United States (53-71%), antenatal women have poor sleep quality.METHODOLOGY: - Using a purposive sampling strategy, the study's pre-experimental one-group pre-test and post-test research design analyzed the healthy sleep habits of 100 pregnant mothers.CONCLUSION: - As a result, the knowledge of antenatal mothers regarding good sleep practices will improve. And this has an impact on mother’s antenatal period.
Case Report on Turricephaly
Authors: Kirti dhale  , Vaishali Taksande  , Ashish Bhagat
Published: November 2022

Turricephaly is regarded as one of the most challenging cranial malformations to treat because increasing intracranial pressure can occur when cranial height is reduced. In typical medical and nursing situations, kids with turricephaly can be identified by thier osteogenesis imperfecta, ophthalmic proptosis, hydrocephalus, and certain facial characteristics such substantial temporal steamrolling, facial asymmetry hypoplasia, and micrognathia.Turricephaly is a rare and potentially fatal autoimmune disease. In the beginning, estimates of turricephaly from antiquity to the present are shown, and in the end, the findings of a personal investigation into the generally disturbed social behaviour and A 4 year male child admited in pediatric department in hospital the patient reported Head swelling, nausea, occipital area swelling, both eyes swelling, and irregular skull form. the primary therapeutic interventions was given to the patient and he was treated with syp zincovit 5 ml BD antibiotic intravenous fluids during hospitalization and the treatment was continued until my final day of care.
Case Report on Dengue Induced Myocarditis
Authors: Kunal Ingole  , SavitaPohekar  , Ashish Bhagat
Published: November 2022

Background: Due to the wide range of clinical symptoms, myocarditis is a difficult diagnosis. Myocarditis can range from mild to severe, resulting in congestive heart failure, arrhythmias, cardiogenic shock, and death. It predicts morbidity and mortality in dengue-infected patients. Case presentation: we presented a 12year old child who came to the pediatric department brought by mother with a chief complaint of high grade Fever insidious onset since 5 days, Episodes of vomiting non projectiles, non-foul smelling contain food particles since 5 days and pain in abdomen more in right hypochondrial region, non-radiating. He has a no previous history of hospitalization.During a physical examination Head to toe examination reveals few abnormalities; the kid is slim and skinny, with a dreary appearance. He is frail and uncooperative.. Though it found that he develop acute myocarditisand the patient treated with antibiotic, antacid , antipyretic, antidiuretic as well as antiemetic.Conclusion: Dengue-induced myocarditis is a serious condition. Through direct virus activity on cardiomyocytes, dengue virus can induce unusual symptoms such as acute myocarditis, cardiogenic shock, and death. Physicians caring for dengue patients should be aware of this potential result. Elevated cTn-I predicts length of stay and in-hospital death in dengue-infected patients. Diabetes, hypertension, low blood bicarbonate, high serum creatinine, and any echocardiographic abnormalities were all linked to poor outcomes in dengue-infected people.
Case Report On paranasal sinusitis with Diabetes mellitus and hypertension
Authors: Samiksha Bhoyar  , Swapna more
Published: November 2022

Background: An inflammation of the mucous membranes in the paranasal sinuses is known as paranasal sinusitis. The facial bones close to, behind, and above the nose have cavities called sinuses. All paranasal sinuses have mucous membrane lining and are joined to the nasal cavities.Case presentation: A 70 years old male came to the Ear Nose Throat department with the chief complaint of generalized headache , dull activity .Also complaint of reduce vision on both eye , blur vision of near by object and unable to see distant object, reduced sensation of smell . Patient had history of Diabetes mellitus since 5 year and having hypertension since 2 year and patient was diagnosed with covid -19 since 5 month back, was hospitalized for 15 days.On arrival physical examination of the face was carried out with shows swelling around both the eye , Nostrils finding are yellowish greenish foul smelling debris in bilateral nostrils septal perforation present posteriorly .MRI and histopathology was done later he was treated antibiotics and analgesic.
A case report on Subacute small Intestinal obstruction secondary to malignant prehepatic flex
Authors: Pawan V Chaple  , Archana Teltumbhde
Published: November 2022

In patients with distributed stomach and pelvic cancers, acute and subacute digestive obstruction is a common occurrence. MBO (dangerous gut check) is predicted to occur in the year 1028. ovarian malignancies account for 5.542 percent of colorectal illnesses and 4% of colorectal cancers. In general, it is estimated to occur in 2% of all patients with a cutting-edge threat. It addresses a pattern of recurrence in some patients and a progression of illness in others. As a result, a show with an entrail check has a significant impact on both patients and their families. This audit depicts the current MBO administration, as well as the clinical, interventional, and careful approaches that are used in combination to improve outcomes in these difficult patients.Case presentation: She is, a 50-year-old Female admitted to rural hospital with the objection of torment in mid-region, Nausea, and regurgitating seance 2 days. The patient has no set of experiences of Hypertension and Diabetes Mellitus Tuberculosis and asthma, Patient was cognizant and situated, All scheduled examination was finished. Patient colonoscopy shows climbing colon friable, lumen impeding mass, and various biopsies taken from the mass. Impression Carcinoma climbing colon. Decisions: A 50-year-old female patient conceded to the emergency clinic with the main grievance of torment in mid-region, Nausea, and heaving seen 2 days. After all examination patient was analyzed as an instance of Subacute little Intestinal obstacle auxiliary to harmful prehepatic flex. Presently she is going to be under treatment. Presently tolerant guess is better compared to past and counsel the patient for the ordinary multi-day follow up.
Polytrauma with Grade-IV Liver Laceration and Grade-II Renal Laceration: A Case Report
Authors: Pema Chuki  , Shalini H. Moon  , Khushbu Meshram  , Archana Dhengre  , Pradnya Sakle  , Roshan Umate
Published: November 2022

Background: One of the leading causes of mortality and morbidity is road accidents. The commonest cause of polytrauma is due to road traffic accidents, other causes may include self-harming activities, suicide, and murder. Nearly two- thirds deaths due to Road Traffic accidents are reported in India mostly in the age group of 15-44 years. Rescue of patients with polytrauma requires maintaining hemostasis while concurrently administering treatments and using proper triage management according to the severity of the injuries, especially in situations of severe trauma with pulmonary contusion and significant blood loss. Massive hemothorax and extensive tracheobronchial hemorrhage result from serious lung injury. Depending on the amount of chest leakage in cases with hemothorax, emergency surgery is advised. Here we report a case of a 20-year-old adult male who was brought by his parents to the emergency department in a conscious state. The patient reported sustained injuries over the face, chest, and left knee. All the necessary laboratory investigations were done after which the patient was shifted to the Surgery Intensive Care Unit. The primary therapeutic intervention was given to the patient and was treated with blood transfusion, antibiotics, antiemetics, and antacids, and a diet was planned during hospitalization.
Case report on Wilson’s disease with hepatic encephalopathy and type 1 hepatorenal syndrome
Authors: Prajwal Bhagat  , Shalini Moon  , Roshan Umate
Published: November 2022

An uncommon inherited condition of copper metabolism is known as Wilson disease. The copper-transporting enzyme ATP7B, which is mostly found in the liver and brain, has undergone several mutations that result in hereditary abnormality. Clinical symptoms are loss of vision for 2 days, and after eye examination, there was a yellowish discoloration in the eye. The patient did not want to eat anything due to the disease condition, and he has been having a loss of appetite for 2 days. Early infancy to young adulthood and even later ages can see the start of the condition. Clinical, biochemical, and molecular indicators are used in conjunction to make the clinical diagnosis. Early or even better pre-symptomatic disease stages are when chelating medicines and zinc salts are most useful as a treatment.
Case Report on Mucoepidermoid Carcinoma of Salivary Gland
Authors: Shaila Bagwe  , Ruchira Ankar  , Ashish Bhagat
Published: November 2022

Background: The most prevalent kind of salivary gland cancer is mucoepidermoid carcinoma. The main clinical signs of Salivary gland mucoepidermoid carcinoma region is characterized by a lump in the face, neck, discomfort in the mouth, or trouble swallowing. The initial therapy is the surgical removal of the whole tumor .and in the final stage of chemotherapy, radiation therapy is also used. A 43year old male came to the medicine unit with complaints of edema all over the right-side face below the right ear since from 1 year. loss of appetite and disturbance in sleeping patterns. As per the patient’s verbalization, he was apparently all right before a year, and after that, he started to show swelling over the right side of the face and below the right ear for 1 year, for he took treatment in the primary health care center. But after 4 months it was not relieved so again, he went to the private hospital where he has treated with anti-inflammatory medications but still got no relief. Later this swelling was associated with the loss of appetite and disturbance in sleeping patterns now after a year he came to the tertiary care hospital for management. Salivary gland cancer represents 5% of total head and neck tissue cancers. tumors. Small salivary gland tumors, which make up 10% to Approximately Malignant salivary gland neoplasms make up 15% of all cases. The second most frequent cancer type is mucoepidermoid carcinoma. tiny tumors of the salivary glands are common. (12–40 percent worldwide).
A REVIEW: MICROEMULSION-BASED POLYMER MATRIX TRANSDERMAL PATCH FOR THE TREATMENT OF INFLAMMATION
Authors: MITTAL R.  , Md. AKHTAR S.  , BEE R.
Published: November 2022

The inflammation is the Immunogenic response when a foreign particle or material or any antigen is entered in the body. The topical delivery or a transdermal delivery is defined as it is a route of administration of a drug via skin or to protect the drug from the metabolism process. The topical formulations are of different types such as lotion, creams, patches, gels and ointments. The transdermal patches are the system where the medicine is diffused from the matrix of polymer and penetrates the skin and the drug shows the therapeutic benefit to the patient. Microemulsion patches are the novel delivery system in which the drug is in micron size ranges and then easily penetrates the skin and becomes a more successful drug delivery over the conventional patches. The microemulsions are the thermodynamically stable biphasic seen as a clear solution in which the drug is entrapped in a dispersed phase and the continuous phase is work as the vehicle for the administration of the dose. There are some tests like entrapment efficiency and Invitro drug release testing for determination of its efficacy. There are some characterization tests like electro conductivity study, rheological properties and centrifugation study has also performed the folding endurance surface pH and the water content and the stability testing has been performed. The microemulsion patch drug delivery system has been found to have more bioavailability and duration of action than the conventional patches or the topical formulation.
The Effectiveness Of Mindfulness On Blood Pressure And Brain Wave Of Elderly People
Authors: Wala Almosawy  , Marwan S Abbas , Abbas Adnan Kamil
Published: November 2022

Blood pressure in the elderly is considered as one of the health disturbing factors. In this study, we seek to evaluate the effectiveness of mindfulness-based therapy on blood pressure and brain waves in the elderly.

Method

The present study was a quasi-experimental with experimental and control groups. In this study, 8 elderly people were trained in 8 mindfulness techniques one by one. The brain waves and blood pressure of the subjects were then compared with those in the control group. In this study, a sphygmomanometer and electroencephalography device were used.

Results

The results showed that the mean blood pressure of the experimental group decreased compared to the control group in the post-test stage. Also, the alpha and theta brain waves of the experimental group increased compared to the control group.

Discussion

According to the findings of the present study, mindfulness method can reduce blood pressure in elderly people with high blood pressure and on the other hand, increase brain waves associated with relaxation, namely alpha and theta.
Assessment Of Some Amino Acids, Metal And Biomarkers In Diabetic Patients With Type2 DM In Thi-Qar Governorate, South Of Iraq
Authors: Doaa Ayaad Khudhair ; Firas Fadel Alyaseen
Published: November 2022

The study was designed to investigate the levels of l-arginine, l-carnitine, zinc, magnesium and chromium in patients with type2 diabetes. 100 samples of peoples with type 2 diabetes aged )17-65( years were used, divided into (50 males and 50 females), and the data was compared with 100 healthy subjects (50 males and 50 females) as a control group. Also, biochemical parameters of fasting blood glucose, serum insulin, serum c-peptide and cumulative hemoglobin HbA1c% were measured for both patients and control groups.  The results indicate that diabetic patients have lowered levels of l-arginine and l-carnitine (88.03± 4.45b, 38.79± 4.18b) sequentially, and zinc, magnesium and chromium (0.54± 0.08b, 1.58± 0.10b, 0.12± 0.02b) sequentially in blood compared with the healthy subjects of control group where the levels of l-arginine, l-carnitine, zinc, magnesium and chromium (107.59± 9.75a, 56.48± 4.08a, 0.90±  0.12a, 1.99± 0.20a, 0.22 ± 0.04a) sequentially, Also there was elevated of levels of fasting blood glucose, serum insulin, serum c-peptide and HbA1c% in diabetic patients (206.85± 33.34a, 27.48± 5.78a, 4.45± 0.81a, 9.09± 1.52a) sequentially compared with the control groups (87.04 ± 9.37b, 16.48 ± 3.64b, 2.66 ± 0.73b, 3.83 ± 0.96b) sequentially.
Anorexia In Hemodialysis Patients
Authors: Mr. Darshan UKalhane . Suhas Tiwaskar , Roshan Umate
Published: November 2022

Anorexia is characterized by a decrease in appetite. One-third of patients on hemodialysis(HD) have anorexia, which is characterized as the lack of the urge to eat. We essentially don't know how the disease started. Leptin, ghrelin, neuropeptides, inflammation, altered amino acid pattern, and uremic toxins as intermediate molecules have all been proposed as potential contributing factors. Malnutrition and cachexia are both facilitated by anorexia, which lowers oral protein and energy intake.

There is no doubt that it lowers life quality.

It is debatable if anorexia has any clinical significance as astandal one prognostic factor in HD patients. The therapy approach used to treat this crippling ailment may include regular dialysis sessions and nutritional advice.

By bringing plasma branched-chain amino acids back to normal with branched-chain amino acid supplementation, anorexia may be reduced and energy and protein intake may be increased... Megestrol acetate's ability to stimulate appetite has to be supported by sufficient randomized studies. Melanocortin-receptor antagonists and subcutaneous ghrelin injection seem like potential treatment approaches.

The uremic syndrome frequently leads to eating and appetite issues, which worsen malnutrition in dialysis patients. According to the findings, uremic anorexia could without the development of visceral and abdominal fatless food consumption. this type of obesity is characterized by The prevalence of intake and malnutrition) is higher in dialysis patients. than obesity brought on by excessive eating.
Case Report On Cirrhosis Of Liver
Authors: Meenal D. Bhoyar , Suhas Tiwaskar , Roshan Umate
Published: November 2022

Introduction: - The liver is irrevocably damaged and replaced with scar tissue as a result of the late-stage liver disease cirrhosis. Scar tissue prevents your liver from functioning properly. Cirrhosis typically develops decades after the onset of chronic liver disease. Men experience it twice as frequently as women. Clinical Findings:-Weakness, loss of appetite, easy bruising, skin yellowing (jaundice), itching, and weariness are all symptoms of cirrhosis. Diagnostic Evaluation: -Blood test: - HB % = 9.3gm%, total RBC count = 2. 99cu.mm, total WBC count = 11800cu.mm, total platelet count = 1.23 lac cu.mm, total protein = 6.5g/L, total bilirubin = 15.8g/L, lymphocytes = 10%, monocytes = 0.2%, albumin =2.2. Peripheral Smear: - RBCs - Normocytic mildly hypochromic Platelets - Reduced on smear APC - 38000 cells/mm³ as per cell counter no Haem parasite seen. Ultrasonography:- Options include liver needle biopsy, ultrasonography, and magnetic resonance imaging (MRI). an innovative imaging technique called electrography. Therapeutic Intervention: - Inj. Albumin 20% × OD, Inj. Vitamin K 10mg ×OD, Inj. Optineuron ×OD, Inj. Pan 40mg × OD, Inj. Emset 4mg × SOS, Inj. Levoflox 500mg × OD.

Outcome: -  After treatment the patient show

Improvement. His appetite is improved and skin condition is also improved and his Weakness is reduced.

Conclusion:- With a known case of liver cirrhosis, the patient was admitted to the hospital with complaints of weakness, loss of appetite, easy bruising, jaundice, itching, and weariness. His condition improved after receiving the proper care.
History Of Malaria
Authors: Bhushan Balvir , Suhas Tiwaskar , Roshan Umate
Published: November 2022

A human victim will get bitten by a female Anopheles mosquito that has been exposed to the malaria-causing Plasmodium parasites. The leading cause of mortality globally is malaria, but in Africa, unfavorable outcomes can be prevented with early detection and timely treatment The most typical illness in Africa is numerous nations Malaria exists in Asia, which is imported from endemic regions in the industrialized world. Beginning in the second century B.C, China used the plant sweet sagewort to treat malaria It took a long time for quinine to be used as malaria prophylactic. The global campaign to eradicate Beginning January 1955, malaria struck Croatia. proclaimed 1964 is slated to be a triumph. Organization for World Health oversees a global malaria prevention program with a focus on improving primary healthcare locally, early illness identification, timely treatment, and disease prevention. Compared to five years ago, malaria is not as common now. However, Malaria cases have increased in recent years. increased significantly around the world. Although the rate of change has slowed, it is still moving in the direction of the WHO's objectives. According to reports, malaria killed 435,000 people and affected 219 million people worldwide in 2017This burden of illness and death is a more than a century-long process's worldwide study and effort aimed towards enhancing the treatment, diagnosis, and prevention of malaria. The most prevalent illness with the biggest number of cases is malaria. Native examples can be seen in various Asian and African nations. Malaria causes 0.3-2.2% of worldwide deaths, and in tropical areas, It may go up to a height of 11–30% of those who suffer from the most severe illness According to several studies, the incidence of malaria parasite infection has increased in 2015.
Deficiency Of Vitamin D In India
Authors: Pranali Babhulkar , Suhas Tiwaskar , Aniket Pathade
Published: November 2022

Vitamin D deficiency (VDD) is a global health issue that affects both industrialized and emerging countries. With prevalence rates across all age categories in India, vitamin D deficiency is across the entire Indian continent. Regardless of the fact that there is sufficient sunlight in India which is required for endogenous vitamin D synthesis. Nutrient D inadequacy is probably going to play a significant part in the exceptionally high pervasiveness of osteoporosis, rickets, cardiovascular disease, diabetes, sicknesses and contaminations like tuberculosis in India. In India, regularly consumed foods only occasionally contain vitamin D supplements such as in dairy products. Numerous factors might contribute to vitamin D deficiency, such as skin color, lack of sunshine exposure, vegetarian eating habits, and low consuming of meals enriched with vitamin D. A sufficient amount of sun exposure, eating dietary sources of vitamin D, and fortifying foods with vitamin D can all help avoid VDD.
Study Effects Of Aqueous Extract Of Local Fenugreek Seeds And Olive Leaves In Some Biochemical Traits At Iraqi Awassi Sheep
Authors: Shadan Abdel Wahab Saleh , Sarmad Abdul Razak Abood Alssadi
Published: November 2022

This study was conducted to determine the effect of using an aqueous extract of local fenugreek seeds and olive leaves on some of the biochemical traits of Iraqi Awassi sheep. Twenty Awassi sheep aged 11-12 months with an average weight of 48.50 kg were used in this study. The ewes of the experiment were divided into five transactions. The duration of the study reached four complete estrus cycles (70 days) with the addition of 14 days at the start of the experiment to unify estrus to make the total days of the experiment 84 days (12 weeks). The animals were randomly distributed into five equal groups with four repetitions in each group as follows: the first control treatment dosed the ewes with distilled water only, T2 the second treatment was dosed with fenugreek seed aqueous extract at a concentration of (25 mg/ ml/ kg), T3 the third treatment was dosed with fenugreek seed aqueous extract at a concentration of (50 mg/ ml/ kg), T4 the fourth treatment was dosed with olive leaf aqueous extract at a concentration of 25 mg/ ml/kg. T5, the fifth treatment, was dosed with an aqueous extract of olive leaves at a concentration of (50 mg/ml /kg). As for biochemical parameters, there was a least significant decreasing (P≤0.05) in blood glucose level in the third treatment and total period in comparing with all other treatments Over the duration of the experiment. T3 recorded a significant superiority (P≤0.05) in total protein compared to other treatment groups. Although there was a decreasing in total protein concentrations of T5 in the third, fourth and total periods compared to T3. No significant differences between all study groups at albumin level except in total period which T5 Outperformed control group. T2 and T3 were recorded significantly decreasing (P≤0.05) in AST and ALT compared to the control group, as for the T5 showed the lowest significant decrease was recorded in (P≤0.05) of all experimental withdrawals. In addition to the moral decline recorded by the ewes of the T4 group compared to the control group from the second withdrawal to the end of the experiment.
Synthesis And Characterization Of New 1,2,4- Triazine Based On 2,5-Dihydrazino-1,3,4- Thiadiazole
Authors: Shaimaa Y. Ibraheam
Published: November 2022

The chemistry of 1,2,4-triazine derivatives received a great deals of attention in recent year due to the use of such ring system as the core structure in many heterocyclic compound covering wide range of applications in many different field especially in industrial and biological fields. An efficient aza Diels-Alder reaction have been used in this presentation to prepare the hetero adducts represented by N2,N5-di(3,5,6-tri aryl-5,6-dihydro-1,2,4-triazine-4(3H)-yl)-1,3,4-thiadiazole-2,5-diamino( 9-20)from hetero dienes and hetero dienophile. However the preparation starting form 1,3,4-thiadiazole-2,5 dithaiole (1) which converted directly to the dihydrazino derivatives(2) which then afford under condensation reaction hetero dienophile represented by 2,5-bis Schiff bases of 1,3,4-thiadiazole(3-6) by its reaction with substituted benzaldehyde . The last compound were reacted through one-pot free solvent aza Diels-Alder reaction with appropriate hetero diene( hydrazine with substituted benzaldehyde in ratio 1:2)  (7&8 )  to afford 1,2,5-triazine derivatives (9-20) using grinding and MWI techniques as a types of green chemistry approaches.