bluuebunny/crossref_metadata_2025 huggingface dataset:
Hydrogels with Tethered Transcription Circuit Elements for Chemical Communication and Collective Computation
Authors: Chen Kuan-Lin , Cole Joshua , Chou Cheng-Hung , Schaffter Samuel W. , Moerman Pepijn , Rubanov Moshe , Sneh Keren , Schulman Rebecca
Published: October 2024

Tissues, robots, and other distributed systems must make decisions about information originating from and then orchestrate responses at different physical locations. Cell-cell communication processes are essential for morphogenesis, immune response, and wound healing. Devising methods for programming analogous distributed behaviors in synthetic materials, such as multi-scale pattern formation or self-assembly, remains a challenge. Here, we devise a design principle for distributed chemical computing and construct a library of transcription circuit elements, termed tethered genelets (TGs), that implement this design principle within networks of 50-micron hydrogel nodes (HNs). TGs exhibit digital behavior in the form of a "distance-response curve" - they switch off in response to signals emanating from an HN within a specific distance but are unaffected by faraway signals. Computational studies show that this property allows HN networks to reliably propagate information without attenuation and to program specific spatiotemporal patterns such as pulses and oscillations with tunable frequencies. In experiments, we verify that TGs send and receive signals as designed and validate the function and modularity of a library of 15 TGs circuit elements. The resulting design principle and library of molecules now provide a means of programming a diverse range of distributed chemical behaviors, allowing for distributed communication and dynamics in soft robots, responsive surfaces, and other bio-materials.
Excited State Structure and Minimum Energy Conical Intersection Optimization Using DFT/MRCI
Authors: Wang Tzu Yu , Neville Simon P. , Schuurman Michael S.
Published: October 2024

The combined density functional theory and multi-reference configuration interaction (DFT/MRCI) method is a semi-empirical selected-CI electronic structure approach that is both computationally efficient and of predictive accuracy for the calculation of electronic excited states and simulation of electronic spectroscopies. However, given that the reference space is generated via selected-CI, a challenge arises in the construction of smooth potential energy surfaces. To address this issue, we treat the local discontinuities as noise within the Gaussian Progress Regression framework and learn the surfaces by explicitly optimizing a white-noise kernel. The characteristic polynomial coefficient surfaces, which are smooth functions of nuclear coordinates even at conical intersections, are learned in place of the adiabatic energy surfaces and are used to optimize the DFT/MRCI(2) minimum energy conical intersection geometries for representative intersection motifs in the molecules ethylene, butadiene, and fulvene. One consequence of explicitly treating the noise in the surfaces is that the energy difference cannot be made arbitrarily small at points of nominal intersection. Despite the limitations, however, we find the structures as well as the branching spaces to compare well with \textit{ab initio} MRCI and conclude that this approach is a viable method to learn a smooth representation of DFT/MRCI(2) surfaces.
The Propionic Chains of Biliverdin Influence Oligomerization in Sandercyanin
Authors: Mainas Eleftherios , Curtin Gregory , Riddles Shaena , Pieri Elisa
Published: October 2024

Sandercyanin is a mildly fluorescent biliprotein with a large Stokes shift, a tetrameric quaternary structure and a biliverdin chromophore that is not covalently bond to the protein. To adapt this promising protein for use in bioimaging, it is necessary to produce monomeric mutants that retain the spectroscopic properties while increasing the fluorescent quantum yield. Modulating these properties through the protonation state of biliverdin’s propionic tails is a possible avenue, if detailed mechanistic information on the role of such chains becomes available. In this study, we use a microstate model for the titration process of biliverdin and couple it with Constant pH Molecular Dynamics to study protonation states in the apo protein, the artificial monomer and the tetramer, and identify shifts. Our results indicate that several residues might have a central role in oligomerization as a response to the presence of biliverdin, and especially to the protonation state of the propionic tails. While the absorption properties are not strongly impacted by the tails, their protonation state has an impact on the chromophore geometry, which likely influences fluorescence.
9-Fluorenylmethoxycarbonyl (Fmoc)-modified taurine as a hydrogelator bearing sulfonate group
Authors: Sugiura Shintaro , Higashi Sayuri L. , Shintani Yuki , Shibata Aya , Hirosawa Koichiro M. , Suzuki Kenichi G.N. , Ikeda Masato
Published: October 2024

Here, we report that a 9-fluorenylmethoxycarbonyl (Fmoc)-modified taurine (Fmoc-Tau) can act as a hydrogelator. The supramolecular hydrogels of Fmoc-Tau were constructed through the self-assembly to form self-assembled fibrous structures under physiologically relevant aqueous conditions. Fluorescence microscopy was employed to investigate the accumulation of basic fibroblast growth factors along the self-assembled fibrous structures.
A Framework for Optimizing Continuous Methane Monitoring System Configuration for Minimal Blind Time: Application and Insights from over 100 Operational Oil & Gas Facilities
Authors: Metzger Noah , Lashgari Ali , Ismail Umair , Ball David , Eichenlaub Nathan
Published: October 2024

Continuous monitoring systems (CMS) that utilize fixed-point sensors provide high temporal resolution point-in-space measurements of ambient methane concentration. This study introduces a modular framework for optimizing CMS configurations, encompassing sensor density (number of sensors) and near-optimal placement. By introducing a metric called ‘blind time’, this study attempts to capture periods where the network fails to make detections that could satisfy the regulatory requirement of quantifying emissions every 12 hours. This framework is then applied to 124 operational oil and gas production facilities with a wide variety of site characteristics and meteorological conditions. This study determines a representative blind time for near-optimum CMS configurations for operational facilities and then investigates the impact of different sensor network densities on the performance of the CMS. The results demonstrate that 3-sensor networks, when placed in near-optimum arrangements, can achieve blind time of less than 10% and a mean time to detection of approximately 82 minutes.
EFFECT OF LAND PREPARATION, WATER MANAGEMENT PRACTICES, AND PLANTING OPERATION ON PLANTING QUALITY IN RICE PRODUCTION
Authors: Mairghany Modather , Elsoragaby Suha , Adam Nor Maria , Yahya Azmi
Published: October 2024

This study was conducted at Sungai Burong Tanjung Karang Kuala Selangor, Malaysia to investigate the effects of planting methods and techniques on planting quality. The problem is that the farmers do not follow Rice Check quality points in land preparations for flooding, drainage, and water depth which affects the planting quality (planting density, spacing, and planting losses). The results showed that following standardized practices has a positive effect on planting quality. Soil penetration resistance and soil bulk density decrease with the increase of the field flooding period and increase with the sedimentation period increase. Soil penetration resistance and bulk density have a negative effect on planting losses. The working speed of the transplanting machine was affected by the field condition SPR, Db, and WC affect the transplanting speed which affects the planting quality (planting density, spacing, and planting losses). The flooding period has a positive effect on planting losses, while the sedimentation period has a negative effect. Floating hills and buried hills decrease with the increase of flooding periods, and water depth, and with the decrease of the sedimentation soil penetration resistance, and soil bulk density. Bulk density and soil penetration resistance have a positive effect on planting density and spacing as they decrease, planting density and spacing decreases, and vice versa. The flooding period has a negative effect on planting density and spacing, while the sedimentation period has a positive effect. About 50.5% of the farmers used the right required amount of water for irrigation, and also the right time for irrigation.
Pengaruh Subtitusi Tepung Uwi Ungu-Kacang Tanah dan Penambahan Cmc (Carboxymethyl Cellulose) terhadap Karakteristik Makaroni
Authors: Cahyono Murti Siti Tamaroh , Marni Marni , Yulianto Wisnu Adi
Published: October 2024

Pembuatan makaroni dengan bahan tepung baku uwi ungu, kacang tanah dan pembahan CMC merupakan pemanfaatan bahan pangan lokal. Tujuan penelitian ini adalah untuk mengetahui perbandingan tepung uwi ungu, kacang tanah dan penambahan CMC terhadap sifat fisik, kimia dan tingkat kesukaan makaroni yang memenuhi syarat dan disukai panelis. Pada penelitian ini membuat makaroni dengan perbandingan penambahan  tepung terigu, tepung uwi ungu dan tepung kacang tanah (100% : 0% : 0%) ; (85% : 10% : 5%) ; (70% : 20% : 10%) ; (55% : 30% : 15%) dan penambahan CMC ( 0,5%,  0,75% dan 1%). Analisa yang dilakukan pada penelitian uji fisik pada makaroni terdiri atas warna dan tekstur. Uji kimia terdiri atas kadar air, kadar abu, kadar protein, aktivitas antioksidan, fenol dan antosianin, serta tingkat kesukaan makaroni. Hasil penelitian menunjukkan bahwa perbandingan  penambahan  tepung terigu : tepung uwi ungu : tepung kacang tanah dan penambahan CMC terhadap makaroni berpengaruh nyata terhadap uji warna, tekstur, aktivitas antioksidan, serta  tingkat kesukaan makaroni. Makaroni dengan perlakuan terbaik yang paling disukai panelis dan memiliki aktivitas antioksidan tinggi yaitu pada perlakuan dengan perbandingan tepung terigu 55: tepung uwi ungu 30: tepung kacang tanah 15 dan penambahan CMC 0,75% memiliki kandungan kadar air  6,85%, kadar abu 3,19%, kadar protein 17,74%, aktivitas antioksidan 64,10 %RSA,  fenol 52,54 mg EAG/100 g dan antosianin 45,06 mg/100 g.
Pengaruh Penambahan Carboxymethyl Cellulose terhadap Karateristik Mi Basah
Authors: Setiyoko Agus , Awaliya Nila Soviatul
Published: October 2024

Ekstrak bunga telang memiliki kandungan senyawa bioaktif yang berperan sebagai antioksidan. Pemanfaatan ekstrak bunga telang dalam mi basah dapat menjadi alternatif sebagai pewarna alami. Penambahan CMC diharapkan dapat meningkatkan tekstur dari mi basah yang dihasilkan. Tujuan penelitian ini adalah menghasilkan mi basah dengan penambahan CMC dan ekstrak bunga telang untuk mengetahui pengaruh penambahan CMC dan ekstrak bunga telang terhadap sifat fisik, kimia dan tingkat kesukaan mi basah yang dihasilkan. Mi basah dibuat dari tepung terigu, CMC, ekstrak telang, garam dan air yang dicampur dan diuleni hingga kalis, kemudian adonan didiamkan, dipipihkan, dipotong menjadi untaian mi dan direbus. Analisis yang dilakukan meliputi pengujian fisik warna, tensile strength, rehidrasi dan rendemen, kadar air, kadar abu, aktivitas antioksidan serta uji kesukaan. Metode penelitian yang dilakukan menggunakan Rancangan Acak Lengkap (RAL) faktorial dengan 2 faktor, faktor pertama konsentrasi penambahan ekstrak bunga telang dan faktor kedua konsentrasi penambahan CMC. Penambahan ekstrak bunga telang sebesar 3%, 6% dan 9%, dan penambahan CMC sebesar 0,5%, 0,75% dan 1%. Data yang diperoleh kemudian dianalisa statistik menggunakan Univariate Analysis of Variance dan apabila terdapat beda nyata dilanjutkan Duncan Multiple Range Test (DMRT). Hasil penelitian menunjukkan bahwa perlakuan terpilih yaitu mi basah dengan penambahan CMC 0,75% dan ekstrak bunga telang 9% dengan karakteristik fisik L* 50,93, a* 0,90, b* 3,81, tensile strength 0,012Mpa, rehidrasi 0,85 g/ml, rendemen 97,30%. Sifat kimia meliputi kadar air 29,15 b/b, kadar abu 0,85 b/b dan aktivitas antioksidan 1,49 %RSA. Mi basah yang disukai panelis adalah mi basah dengan penambahan ekstrak bunga telang 9% dan CMC 0,75%.
Jahe Emprit Instan Dengan Variasi Waktu Blanching dan Penambahan Ekstrak Serai
Authors: Gesta Andika Laura  , Dwiyati Pujimulyani  , Siti Tamaroh
Published: October 2024

Rimpang jahe (Zingiber officinale var amarum) mengandung senyawa antioksidan seperti fenol, dan flavonoid dan minyak atsiri dapat mencegah penyakit degenerative dan antimikroba. Tujuan penelitian yaitu menghasilkan minuman jahe emprit instan dengan penambahan ekstrak serai dan lama waktu blanching terpilih yang disukai dan mempunyai aktivitas antioksidan. Penelitian dilakukan dengan Rancangan Acak Lengkap 2 faktor yaitu penambahan ekstrak serai (10, 20 ml) dan lama waktu blanching (0, 5, 10 menit). Minuman Jahe emprit instan kemudian dianalisis fisik dan tingkat kesukaan. Data penelitian diuji statistik menggunakan Analysis of Variance (ANOVA) dan Duncan Multiple Range Test (DMRT) dengan tingkat signifikasi 5%. Sampel terpilih dianalisis sifat kimia yaitu kadar air, aktivitas antioksidan, dan fenol total. Hasil penelitian menunjukkan bahwa penambahan ekstrak serai dan lama waktu blanching berpengaruh nyata terhadap warna dan uji kesukaan minuman jahe emprit instan. Minuman jahe emprit instan terpilih yaitu dengan penambahan ekstrak serai 20 ml dan lama waktu blanching 10 menit memiliki nilai kadar air 0,86% bb, aktivitas antioksidan 18,06% RSA, dan fenol total 6,47 mg EAG/g bk.
Karakteristik Sari Buah dengan Variasi Rasio Labu Kuning-Apel-Nanas dan Lama Pasteurisasi
Authors: Salsabila Yumna , Slamet Agus Slamet , Kanetro Bayu
Published: October 2024

Sari buah merupakan minuman yang diperoleh dengan mencampur air minum, sari buah, atau campuran sari buah yang tidak difermentasi, dengan bagian lain dari satu jenis buah atau lebih, dengan atau tanpa penambahan gula, bahan pangan lainnya, dan bahan tambahan pangan yang diizinkan. Sari buah dibuat dari campuran labu kuning, apel, dan nanas untuk meningkatkan kualitas gizi dan sensori. Tujuan penelitian untuk mengetahui variasi rasio labu kuning-apel-nanas, dan lama pasteurisasi terhadap sifat fisik, kimia, serta tingkat kesukaan sari buah yang memenuhi syarat serta disukai panelis. Rancangan pola faktorial digunakan dalam penelitian ini. Faktor pertama adalah rasio labu kuning-apel- nanas, 1:1:1, 2:1:1, dan 3:1:1. Faktor kedua adalah lama pasteurisasi, yaitu 10, 15, dan 20 menit. Hasil penelitian menunjukkan variasi rasio labu kuning-apel-nanas serta lama pasteurisasi berpengaruh nyata terhadap kekeruhan, warna, dan tingkat kesukaan kecuali pada parameter aroma sari buah. Sari buah yang paling disukai panelis yaitu dengan rasio labu kuning-apel-nanas 3:1:1, dan lama pasteurisasi 10 menit yang memiliki pH 4,04, kadar vitamin C 6,78 %b/v, aktivitas antioksidan 21,32 %RSA, dan kadar beta karoten 1,29 μg/g.
Pengaruh Jenis dan Konsentrasi Penambahan Penstabil terhadap Karakteristik Es Krim Alpukat (Persea Americana Mill)
Authors: Yohanes Bayu  , Suryani Lilis , Ichlasia Ainul Fitri
Published: October 2024

Bahan baku es krim pada umumnya adalah susu sapi, yang banyak mengandung laktosa yang merupakan salah satu jenis alergen. Oleh karena itu saat ini banyak dikembangkan es krim dengan bahan dasar susu nabati dan buah-buahan. Salah satu alternatif bahan baku nabati dalam pembuatan es krim nabati adalah bubur buah alpukat. Kandungan lemak alpukat bersifat lunak/lembut, sehingga dapat membentuk tekstur yang baik pada es krim, Namun kandungan asam oleat yang tinggi dapat menyebabkan es krim yang dihasilkan mudah meleleh sehingga untuk memperbaiki hal tersebut diperlukan stabiliser. Zat penstabil memiliki peranan sebagai penstabil dalam proses pencampuran bahan baku es krim, menstabilkan molekul udara dalam adonan es krim, dengan demikian air tidak akan mengkristal, dan lemak tidak akan mengeras. Zat penstabil yang umum digunakan dalam pembuatan es krim adalah CMC, gelatin, karagenan, gum arab dan pectin. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan kombinasi dua faktor, yaitu jenis pestabil yang terdiri dari tiga jenis: CMC; gum arab; karagenan; dengan 2 konsentrasi zat pestabil yaitu 0,25%; 0,50% dan 0,75% dengan dua kali ulangan. Hasil penelitian menyatakan bahwa es krim alpukat dapat dihasilkan dengan penambahan penstabil CMC. Secara khusus hasil penelitian didapatkan: a) Interaksi antara variasi konsentrasi dan jenis penstabil berpengaruh nyata terhadap total padatan, kadar protein, kadar lemak dan tingkat kesukaan es krim alpukat yang dihasilkan. b)  Semakin besar konsentrasi pestabil CMC dan gum arap total padatan es krim alpukat semakin besar, namun pada 0,25 dan 0,50% tidak berbeda nayata; c) Semakin besar konsentrasi penstabil kadar protein dan lemak juga semakin besar, namun jika lebih dari 0,5% menurun kembali, d) berdasarkan tingkat kesukaan diketahui bahwa es krim yang terbaik diperoleh dari es krim alpukat yang dibuat dengan penambahan penstabil CMC 0,5% yang mempunyai total padatan 0,25%b/b, kadar protein 0,75%b/b dan kadar lemak 0,50%b/b. Saran perlu ditindak lanjut untuk sifat fisik es krim yang dihasilkan.
Conscious Techniques Affected the Adolescent’s Ability In Early Breast Cancer Detection
Authors: Andi Hayyun Abiddin Andi , Mujito  , Wulandari Ning Arti
Published: October 2024

Breast cancer is a malignant tumor and grows in the breast tissue resulting in death. Breast cancer prevention by means of breast self-examination. This study aimed to determine the effect of video media on conscious techniques with a combination of demonstrations on the practical ability of adolescents in early detection of breast cancer. The method used a quasi-experimental design, non-equivalent control group design with a population of 279 and a sample of 40 respondents with inclusion criteria of young women, aged 16 years as students of SMA Negeri 1 Tarik Sidoarjo. The data collection measured skills in 2 groups of respondents. The experimental intervention group used videos and demonstrations, while the intervention control group used lectures and leaflets. The intervention was done in 1 day, the posttest was conducted 7 days after the intervention. The results showed that the average value of the pretest posttest of the two groups increased. The results of the statistical test paired T-Test obtained a significant value of p-value = (0.000 < 0.05) meant that there was an effect of providing video media with conscious techniques with a combination of demonstrations on the practical ability of adolescents in early detection of breast cancer. Educators should develop programs to improve skills for early detection of breast cancer, in collaboration with health workers through health promotion so that all students are aware of health.
The role of autonomic imbalance in the pathogenesis of hypertension and the therapeutic effectiveness of renal denervation (literature review)
Authors: Skomkina I. A. , Mordovin V. F. , Falkovskaya A. Yu. , Zyubanova I. V. , Lichikaki V. A. , Manukyan M. A. , Solonskaya E. I. , Vtorushina A. A. , Khunkhinova S. A. , Afanasiev S. A.
Published: October 2024

Arterial hypertension (AH) remains a global problem of modern healthcare, since, despite advances in clinical pharmacology and the use of modern antihypertensive drugs, it continues to be a major risk factor for cardiovascular complications. This necessitates a more in-depth study of the pathogenetic mechanisms of this disease and the development of new pathogenetically based methods of its treatment. Every year more and more studies are published, the results of which indicate the significant role of autonomic imbalance in the pathogenesis of the disease. The article presents the main modern data concerning the study of this problem. A detailed analysis of works devoted to the role of sympathetic hyperactivation in a sustained increase in blood pressure (BP) and the development of pharmacotherapy-resistant forms of hypertension (RAH) was carried out. Particular attention is paid to the influence of modern endovascular methods on changes in the severity of immunoinflammatory processes, through the activation of which the hypertensive effects of increased activity of the sympathetic nervous system are realized. Possible mechanisms of the therapeutic effectiveness of renal denervation and prospects for further clinical application of the method are described.
Possibilities of mitochondrial dysfunction diagnosis in chronic heart failure
Authors: Garganeeva A. A. , Kuzheleva E. A. , Tukish O. V. , Vitt K. N. , Andreev S. L. , Muslimova E. F. , Korepanov V. A. , Afanasiev S. A. , Gulya M. O. , Syromyatnikova E. E. , Vladimirova E. A. , Stepanov I. V.
Published: October 2024

The article presents preliminary study results of association of direct ultrastructural characteristics of mitochondria (MTC) in cardiomyocytes and indirect signs of mitochondrial dysfunction with clinical course and outcomes of chronic heart failure (CHF). According to electron microscopy of the myocardium a violation of the ultrastructure of MTC of cardiomyocytes is accompanied by a decrease in the rate of oxygen absorption by mitochondria of leukocytes of peripheral blood, separation of oxidation and phosphorylation processes, an increased rate of radiopharmaceuticals leaching from myocardium, indicating mitochondrial membrane damage, low tolerance to physical load and reduced oxygen consumption at peak of load test, which confirms the feasibility of studying associations of indirect signs of mitochondrial dysfunction with ultrastructural changes in the mitochondrial cardiomyocytes and clinical manifestations of heart failure.
Development of Intellectual Testing for Electric Motor Installation in Vocational Education
Authors: Taruno Djoko Laras Budiyo , Nugroho Nur Rohman Eko
Published: October 2024

This study aims to understand the functionality of computerized adaptive testing software based on a website application model for the competency of electric motor installation in vocational education. The research method in this research uses research and development and the waterfall model. The research subjects are teachers and students in the electric motor installation subject. Data collection is done using the Noeeriat software instrument. The results of this study are as follows: (1) This tool can function well. This is indicated by testing on the authority of teachers (86.22%) and students (87.50%). (2) The usability level of the tool is considered very feasible in terms of functionality, display, and usefulness. (3) This tool contributes to an improvement in student learning outcomes. This tool can be used to measure the level of students' competency achievement, as a basis for compiling progress reports on learning outcomes, and as a foundation for improving the learning process.
TRANSFORMATIVE IMPACT OF THE DIGITAL AGE ON YOUTH MENTAL HEALTH: NAVIGATING CHALLENGES AND EMBRACING SOLUTIONS
Authors: Tamrakar Latika , Tamrakar Samiksha , Thakur Varsha
Published: October 2024

The digital age has significantly altered the landscape of communication, work, and social interaction, particularly impacting the younger generation. While digital advancements offer numerous benefits, they also introduce challenges to mental health. This paper explores the impact of digital technology on youth mental health, emphasizing social media pressures, digital addiction, cyberbullying, Fear of Missing Out (FOMO), and information overload. It further examines the role of educational institutions in promoting digital literacy and responsible online behavior. By reviewing current literature and proposing interventions, this study provides a comprehensive understanding of how society can mitigate the adverse effects of the digital age on youth mental health.
FROM LOOM TO CLASSROOM: EXPLORING THE EDUCATIONAL POTENTIAL OF JOLAHA ART OF WEAVING'S EMBEDDED MATHEMATICAL CONCEPTS
Authors: Sharma Pankaj , Verma Sunil
Published: October 2024

One of the current challenges in mathematics education is how to link school mathematics to student’s culture and everyday activities to improve the quality of the student’s mathematical learning. Drawing ideas from scholarship in ethno-mathematics, this study attempted to comprehend the mathematical concepts embedded in the weaving art of jolaha peoples. The study employed a qualitative research method to unravel the mathematical elements. Evidence of mathematical practices of the Jolaha community in the art of weaving indicated that irrespective of the mathematical experience, they all employed a certain level of informal mathematics in the discharge of their duties. The researcher explored the Jolaha weaving skills from a mathematical perspective and noted the mathematical ideas, concepts of traditional counting systems, traditional measurement units, concepts of translation, and rhombus that can be used to teach mathematics through ethno-mathematical strategies in the classroom, and concluded with discussion of mathematical elements that can be integrated with the mathematics curriculum to enhance mathematics teaching in the classroom.
Türkiye'deki Bankaların Hisse Senedi Fiyatını Etkileyen Finansal Faktörler
Authors: Abdelfattah Saeed , Aktaş Metin
Published: October 2024

Pay senedi fiyatlarını etkileyen faktörlerin tahmin edilmesi, sürdürülebilir karlılığı sağlayacak yatırımların seçilmesi açısından önem arz eden bir konudur. Dolayısıyla bu çalışmanın amacı, Türk bankacılık sektöründe bankaların pay senedi fiyatları üzerinde etkili olan finansal oranları tespit etmektir. Bunun için 2015-2023 dönemini kapsayan veriler ile panel veri analizi yapılmaktadır. Analizde Türk bankacılık sektöründe faaliyet gösteren 10 mevduat bankasının yıllık finansal oranları, Breusch ve Pagan Lagrangian çarpanı testi, Breusch Pagan ve Cook Weisberg testi, Wooldridge otokorelasyon testi ve Arellano-Froot-Rogers tahmin yöntemi ile analiz edilmektedir. Çalışmanın sonuçları, toplam mevduat/toplam aktifler, net kar (zarar)/toplam aktifler ve faiz gelirleri/faiz giderleri oranlarının pay senedi fiyatları üzerinde pozitif bir etkiye sahip olduklarını, finansal aktifler (net)/toplam aktifler, toplam krediler/toplam aktifler ve likit aktifler/toplam aktifler oranlarının ise pay senedi fiyatı üzerinde negatif bir etkiye sahip olduklarını göstermektedir.
Dynamic Fluid Module: Problem-Based Learning Combined with STEM to Increase Students' Scientific Creativity
Authors: Suyidno Suyidno , Hadianti Raisa , Miriam Sarah , Siswanto Joko
Published: October 2024

Scientific creativity is one of the main competencies in 21st century life, but this competency is not practiced in schools. This study aims to describe the effectiveness of dynamic fluid module using STEM-PBL to improve students' scientific creativity. This module contains lesson plans, module content, materials and scientific creativity tests. This research includes research and development using an adaptation of the ADDIE model. The research trial used a one group pretest and posttest design on 21 students of class XI IPA 1 SMA Negeri 1 Takisung. Data were obtained from student learning outcomes tests, with module effectiveness of 0.41 in the moderate category. Thus, the dynamic fluid module using STEM-PBL developed is effective for increasing students' scientific creativity.
Development of Student Handbook on the Extraction of Secondary Metabolites Based on Premna serratifolia Research
Authors: Auliany Shella , Hadiarti Dini , Kurniawan Rizmahardian Ashari
Published: October 2024

This study aims to develop a digital module on the extraction of secondary metabolites based on P. serratifolia research as a self-study resource for students. This study utilized the Thiagarajan 4D development model, which encompasses the stages of definition, design, and development without dissemination. Participants in the study comprised students from Universitas Muhammadiyah Pontianak, Akademi Farmasi Yarsi Pontianak, and Universitas Tanjungpura who had previously studied extraction materials. Subject matter, media, and language experts provided validity scores of 94.69%, 88%, and 84.37%, respectively, resulting in an average validity score of 89.02%, categorizing the student handbook as highly valid. Small and large group trials yielded practicality percentages of 93.81% and 93.69%, respectively, with an average score of 93.75%, indicating the student handbook high practicality. Consequently, the student handbook on secondary metabolite extraction based on P. serratifolia research is deemed highly valid and practical as a self-study resource on the topic.
Strengthening Marketing Strategies in Organic Agricultural Products Through Organic Farmer Training in Indonesia
Authors: Setiawan Zunan , Dharmawan Donny , Ariani Dian , Ekasari Silvia , Munizu Musran
Published: October 2024

This Community Service (PKM) activity aims to improve the marketing skills of organic plant farmers in Indonesia through online training focused on digital marketing strategies, branding development, and distribution network expansion. The method used was participatory training, involving 30 farmers as a sample, with data collection carried out through pre-test and post-tests to measure changes in participants' knowledge and skills. The results showed a significant improvement in participants' understanding of organic product marketing, with the average pre-test score of 2.5 increasing to 4.2 in the post-test. This increase is mainly seen in the ability of participants to utilize social media and e-commerce platforms to market their products. In addition, qualitative interviews showed that participants felt more confident in developing product branding and expanding marketing networks, although challenges related to internet infrastructure were still faced in some areas. Post-training mentoring also provides additional support that helps participants implement the strategies learned. In conclusion, this training is efficacious in improving the marketing skills of organic farmers. It can be a model that can be applied more widely to strengthen the competitiveness of organic agricultural products in Indonesia.
Some Characteristics Properties for Linear Operator on Class of Multivalent Analytic Functions Defined by Differential Subordination
Authors: Swayeh Ghali Zainab , Kareem Wanas Abbas
Published: October 2024

The purpose of this paper is to consider a linear operator and define a certain class  of analytic and multivalent functions in the open unit disk associated with differential subordination. Also, we discuss some geometric properties for this class.
Dynamical Properties of Rough Group Spaces
Authors: Hatef Fahem Eman , Hameed Hamzah Sattar
Published: October 2024

Our main aim  is introduced some concepts in dynamical system in rough theory . We give the definition of periodic points and critical points and investigate their properties in rough  actions . Also, we illustrated the relation between them.
ESTUDO DA INFLUÊNCIA DOS PARÂMETROS DE PROCESSO NAS CARACTERÍSTICAS DE PEÇAS DE PLA FABRICADAS POR FDM
Authors: Silva Renata Sobrado Jabour Braz da , Barbosa Patrícia Alves
Published: October 2024

A popularização da manufatura aditiva (MA) no segmento industrial se deve ao fato deste processo de fabricação avançado possibilitar a obtenção de peças com geometrias complexas, customizadas com otimização da resistência/peso, além do uso eficiente de matéria-prima e redução de resíduos. Dentre as tecnologias de MA, a modelagem por fusão e deposição (FDM – Fused Deposition Modeling) se destaca por ser a tecnologia mais difundida de fabricação por extrusão de peças termoplásticas, apresentando a melhor relação custo-benefício, devido à simplicidade de funcionamento, com componentes e insumos relativamente acessíveis. Apesar de todas as vantagens, é conhecido que componentes fabricados por MA apresentam características anisotrópicas, relacionadas diretamente com as variáveis de entrada do
processo, o que impacta fortemente as propriedades da peça. Nesse contexto, o presente trabalho teve por objetivo avaliar a influência dos parâmetros de processo nas propriedades mecânicas de amostras de PLA (poliácido láctico) fabricadas por FDM. O polímero PLA, foi definido para a presente investigação, por ser um dos principais materiais usados na fabricação por manufatura aditiva. Este termoplástico traz vantagens
como bom acabamento superficial, alta dureza superficial e resistência à abrasão. Para tanto, foram fabricadas amostras em diferentes condições de processamento, com 100% de preenchimento, variando-se a temperatura de extrusão e a velocidade de deposição, e avaliadas as respostas dos corpos de prova submetidos à ensaios de tração e dureza Shore D. Concluiu-se que os resultados de limite de resistência à tração e limite de resistência a ruptura não possuem influência em relação aos parâmetros estudados. Já os resultados do módulo de elasticidade, alongamento e dureza Shore D, mostram influências significativas.
EDITORIAL
Authors: Borges Jorge Amaro de Souza
Published: October 2024

É com grande satisfação que apresentamos a edição do primeiro semestre de 2024 da
Revista Apae Ciência. Este número é especialmente dedicado à inclusão sob suas múltiplas
dimensões e às diversas abordagens para melhorar a qualidade de vida das pessoas com deficiência, sobretudo a partir da relação entre teoria e prática. A Revista Apae Ciência se destaca,
justamente, por trazer textos que refletem as práticas institucionais do movimento apaeano,
fazendo um importante diálogo com a pesquisa científica. A seguir, organizamos os artigos por
temas, facilitando a navegação e a compreensão dos diversos trabalhos e pesquisas realizadas.
A HIDROCINESIOTERAPIA COMO RECURSO AUXILIAR AO APRIMORAMENTO MOTOR DE PACIENTES COM TEA
Authors: Almeida Neto Leonidio Lins de , Leite Junior Adênio de Almeida , Araujo Rosália Maria Lins , Silva Paula Fracilene Mota Soares da , Veloso Ágata Brendel Pessoa
Published: October 2024

CO Transtorno do Espectro Autista (TEA) ocasiona alterações motoras, comunicativas
e sociais. Objetivou-se prover, com a hidroterapia, a melhoria motora funcional de pacientes
com TEA. Tratou-se de um estudo observacional, descritivo, em uma série de casos, sendo selecionados três pacientes da APAE-JP que apresentaram diagnóstico do TEA. As intervenções
foram feitas semanalmente, por quatro meses, sendo relevante a sua aplicação, indicando ampla
melhoria das habilidades motoras e sociais.
A FORMAÇÃO CONTINUADA DE DOCENTES DA EDUCAÇÃO INFANTIL COM VISTAS A UMA PRÁTICA INCLUSIVA PARA ESTUDANTES COM DEFICIÊNCIAS
Authors: Rocha Aline Cristina Viana , Petronílio Cacilda Nogueira , Meireles Caroline Vanizia , Couto Maristela Santana , Jesus Viviane Soares de , Nonato Gleides Ander
Published: October 2024

Este artigo é o resultado de um estudo que buscou analisar e discutir a importância da
formação continuada como uma ferramenta na busca por uma escola inclusiva, bem como verificar a associação entre teoria e prática como um facilitador diante dos desafios enfrentados
pelos profissionais que atuam na Educação Infantil. Partindo do pressuposto de que para haver
inclusão de fato é necessário que haja formação dos profissionais e de que ela seja continuada
tendo em vista a sua relevância para além da formação inicial, buscou-se responder à seguinte
pergunta: Quais são os impactos da formação continuada dos docentes na busca pela inclusão
de estudantes com deficiências matriculados na Educação Infantil? Especificamente, o objetivo
deste estudo foi analisar e discutir a importância dessa formação para os profissionais que atuam
com a inclusão de estudantes com deficiências na Educação Infantil, a partir das percepções de
diferentes autores que se debruçam sobre o tema. Neste sentido, a metodologia utilizada foi
uma revisão bibliográfica com abordagem qualitativa e de cunho descritivo. Dentre as constatações, observou-se que a formação continuada de professores facilita e possibilita a melhoria na
inclusão dos alunos com deficiências, tendo em vista que essa modalidade de formação oferece
instrumental para o aprimoramento da ação dos professores no ambiente escolar
A EDUCAÇÃO AO LONGO DA VIDA EM PARCERIA COM O SERVIÇO DE PROTEÇÃO SOCIAL ESPECIAL PARA AS PESSOAS COM DEFICIÊNCIA INTELECTUAL IDOSAS E AS SUAS FAMÍLIAS, NA PROMOÇÃO DA QUALIDADE DE VIDA NO PROCESSO DE ENVELHECIMENTO
Authors: Oliveira Adriana Daiana de
Published: October 2024

A parceria entre Educação ao Longo da Vida e o Serviço de Proteção Social Especial
para Pessoas com Deficiências, Idosas e Suas Famílias desempenha um papel crucial na promoção da inclusão, no fortalecimento de habilidades e no apoio a famílias. Este artigo é um
relato de experiência do serviço socioassistencial desenvolvido pela APAE de Irani-SC, que
explora a importância de promover a habilitação e reabilitação no campo da assistência social
para pessoas com deficiência intelectual em processo de envelhecimento e como a colaboração
entre a educação e os serviços de proteção social especial pode enriquecer suas vidas. A cooperação entre essas duas áreas permite uma abordagem personalizada para atender às necessidades específicas de cada indivíduo. Além disso, a troca de conhecimentos entre profissionais da
educação e assistência social pode levar a estratégias mais eficazes para melhorar a inclusão, a
aprendizagem e o desenvolvimento.
EFICIÊNCIA DOS JOGOS INFANTIS NA APRENDIZAGEM DA MATEMÁTICA
Authors: Oliveira Elaine de , Sousa Maria de Jesus Rodrigues de , Silva Naira Franciely Morais , Pereira Valéria Fernandes
Published: October 2024

Este artigo explora os jogos lúdicos no ensino da matemática nas séries iniciais. Baseado em uma revisão bibliográfica, o estudo analisa como jogos educativos podem melhorar o desenvolvimento pedagógico e o raciocínio lógico de crianças com dificuldades de aprendizagem. O objetivo é investigar a eficiência dos jogos infantis, no desenvolvimento de habilidades matemáticas e na promoção do interesse pela disciplina. A metodologia adotada inclui uma revisão de literatura sobre a aplicação de jogos no ensino da matemática e a análise de estudos de caso que demonstram sua eficácia. Os materiais e métodos utilizados envolvem a aplicação de jogos matemáticos em ambientes escolares e a observação de seus efeitos sobre o desempenho dos alunos. Os resultados indicam esses jogos, facilitam a compreensão de conceitos matemáticos abstratos, promovem a prática de habilidades matemáticas de forma divertida e interativa, e aumentam o engajamento e a motivação dos alunos. A conclusão ressalta que a integração de jogos na educação matemática não só melhora o desempenho acadêmico das crianças, mas também torna o aprendizado mais agradável e eficaz.
Palavras-chave: Matemática. Jogos lúdicos. Desenvolvimento. Aprendizagem
ESTUDO DE CASO - O PROCESSO LEGISLATIVO EM TERESÓPOLIS – INCONSTITUCIONALIDADES PRETÉRITAS E PROSPECÇÕES LEGÍSTICAS
Authors: Santos Fernando Rangel Alvarez dos , Quintanilha Andressa Lima , Patricio João Matheus de Lellis Silva
Published: October 2024

A presente investigação teve por contexto analisar o processo legislativo, especialmente no Município
de Teresópolis, nos últimos 05 anos, tendo por objetivo geral: analisar os motivos determinantes que conferem fundamento a declaração de inconstitucionalidade/constitucionalidade das leis municipais de Teresópolis,
analisando pontualmente se o processo legislativo está ou não, na sua gênese, respeitando a Constituição da
República. A metodologia envolveu a coleta de dados por meio de análise quantitativa, apurando o quantitativo
de projetos de lei que tiveram o veto do Poder Executivo derrubado ou mantido. Na abordagem qualitativa, a
partir dos dados acima pesquisados, analisaram-se as motivações das inconstitucionalidades constatadas, tanto
por parte do Poder Executivo, como do Poder Judiciário, relacionadas ao processo legislativo (vício de iniciativa, vício material etc). A pesquisa encontra-se no estado da arte, não havendo percepções dos resultados por
ora, todavia pretende-se perquirir, se possível, a criação de possíveis soluções procedimentais, sobretudo para
possibilitar um diálogo entre os poderes constituídos.
A VOLATILIDADE DE FUNDOS DE INVESTIMENTO APÓS A PANDEMIA DA COVID-19
Authors: Fonseca Danilo Amaral da , Fernandes Priscila Pereira , Marques Filipe Medas , Barata Victor José Pires , Ramos Eliza Rosa de Oliveira
Published: October 2024

A Covid-19 teve seu primeiro caso confirmado no Brasil em fevereiro de 2020, chegando atualmente aos
mais de 28 milhões de casos, tendo seu estado elevado a pandemia em março de 2020. Neste cenário, destaca-
-se a taxa de juros e inflação, de modo, que neste período, ambas apresentaram comportamento de mudanças
significativas, estando a Selic em 10,75% ao ano e o IPCA em 10,38% nos últimos 12 meses. O objetivo geral
desta pesquisa foi investigar uma possível mudança na rentabilidade dos fundos de investimento no Brasil após
a pandemia da Covid-19. Esta pesquisa utilizou uma abordagem quantitativa. A coleta de dados foi através do
site da CVM, com utilização de Software Excel para tabulação. Para análise dos dados foi utilizado teste t para
diferença de médias. De acordo com os dados coletados, não se pode afirmar que a rentabilidade média dos
fundos tenha sofrido alteração entre os dois períodos. Isso não significa que fundos de outras categorias, como
ações, multimercado ou imobiliários, tenham tido comportamento semelhante. Os resultados encontrados corroboram com os conceitos teóricos apresentados, destacando-se que, mesmo em um cenário de incertezas, os
fundos de investimento de renda fixa não apresentaram mudanças significativas em sua rentabilidade.
Cerca de meio século depois: as políticas de consumidores na União Europeia
Authors: Frota Mário
Published: October 2024

Resumo: O objectivo é o de passar em revista as políticas de consumidores da Europa das Comunidades e da União que se estendem por cerca de meio século. No seu núcleo essencial, os direitos fundamentais erigidos em Carta, tal como o pre
dispusera o Conselho da Europa em 1973 e a Comunidade Económica Europeia no programa preliminar em 1975: o direito à protecção e assistência [a protecção contra danos físicos causados por produtos perigosos, a protecção contra danos cau
sados nos interesses económicos dos consumidores], o direito de indemnização por prejuízos, o direito à informação, à educação e à representação e consulta. A análise do plano preliminar de acção e dos que se lhe seguiram: com o advento do Tratado
de Maastricht e o Acto Único Europeu se ensaiam outros rumos e principia o ciclo dos planos trienais, do de 1990-92 ao de 1999-2001, com o Tratado de Amesterdão.
O Tratado de Nice acomoda o Plano Quinquenal 2002-2006, esboçando-se subsequentemente, os planos de 2007-2013 e 2014-2020. Em 2020, surge o plano ora em execução – o de 2021-2025 -, de cujos eixos se realça quer a transição Ecológica na esteira da sustentabilidade, que os Objectivos do Milénio elegem de modo peculiar,
quer os notáveis progressos da transformação digital que há que assistir desvelada
mente na reconfiguração dos cenários sobre que se projecta a sociedade de consumo
na sua absorção pelo digital. O pano de fundo da sociedade digital há-de enformar as novéis relações de consumo que se transferem da órbita analógica para a digital com
os desafios que aí se postulam.
Palavras-chave: Direitos do Consumidor. Políticas do Consumidor. União Europeia. Plano de Acção Preliminar. Plano Quinquenal 2021-2025
O modelo europeu de resolução alternativa de conflitos de consumo: reflexões para o MERCOSUL
Authors: Squeff Tatiana Cardoso , Silva Bianca Guimarães
Published: October 2024

Resumo: O uso da internet vem modificando as relações sociais em todas as áreas, inclusive no mercado de consumo, de modo que o número de obrigações contraídas
através do meio cibernético é cada vez maior. Com isso, surge a necessidade de o Direito readaptar-se frente a essa realidade, buscando novas formas de responder aos
conflitos de consumo que tem neste ambiente o seu ponto de partida.
De nuevo en torno al tema de la protección de datos en la Unión Europea
Authors: Pozo Carlos Francisco Molina del
Published: October 2024

Resumen: El presente trabajo examina, de manera detallada, el marco normativo de la protección de datos en el ámbito de la Unión Europea, con un enfoque central en el Reglamento General de Protección de Datos y los derechos asociados. Se ana lizará la jurisprudencia más destacada del Tribunal de Justicia de la Unión Europea (TJUE), destacando asuntos clave que han influido en la interpretación y aplicación
de las leyes de privacidad.
Effects of Preoperative Training on Static and Dynamic Balance among Female Athletes with Injured ACL
Authors: Parastoo Shamseh Kohan , Heidar Sadeghi , Maziar Meghdadi
Published: October 2024

Aims: The purpose of this research was to study the effects of preoperative training on static and dynamic balance among female athletes with injured ACLs. Methods: This semi-experimental study involved a 2-group pretest-post-test design. Subjects were 36 (19 control and 17 experimental) female athletes with injured ACLs, that were chosen with the available sampling method. The experimental group did the preoperative training in the eight weeks and the control group did not participate in any training program during this period. Static and dynamic balance and lower body muscle strength were measured. The paired sample T-test was used to compare pre and post-test results and the independent sample T-test achieved comparisons between the two groups. Results: The results indicated that static (with eyes opened and closed) dynamic balance and muscle strength were improved significantly (p < 0.05) in the exercise group, but no significant change (p > 0.05) was found in the control group. Also, significant differences were found in improvement changes results between the two groups (p < 0.05). Conclusion: Results of the study confirmed that preoperative training can have a beneficial effect on improving static and dynamic balance among female athletes with injured ACLs.
Pemanfaatan Website UMKM Unggulan Desa Karangbendo Kabupaten Banyuwangi sebagai Sarana Penunjang Kegiatan Promosi
Authors: Ratri Indira Nuansa , Ratri Arum Andary , Prasetyo Junaedi Adi , Fahrurrozi Rahmad , Rentianto Tresnarai Juniarizky
Published: October 2024

Desa Karangbendo merupakan salah satu desa di Banyuwangi yang pendapatannya bertumpu pada Tanah Kas Desa, Hasil Swadaya, dan Partisipasi masyarakat. Permasalahan yang dialami oleh mitra berdasarkan hasil analisis situasi yang telah dilakukan antara lain: Pemasaran asosiasi UMKM Unggulan masih tradisional, minimnya pengetahuan tentang strategi peningkatan brand awereness, dan tidak adanya profil asosiasi UMKM Unggulan Desa untuk kegiatan pemasaran. Berdasarkan beberapa permasalahn yang dialami, tim pengabdi mengusulkan beberapa solusi untuk mitra yaitu: pembuatan website pada UMKM Unggulan Desa Karangbendo dan memberikan pelatihan pada pengisi konten website secara kolektif pada lima UMKM Unggulan Desa Karangbendo. Untuk menerapkan solusi tersebut, maka tim pengabdi melakukan beberapa metode antara lain: Metode pelaksanaan pembuatan website asosiasi UMKM Unggulan Desa Karangbendo, metode pelaksanaan pembuatan video asosiasi UMKM Unggulan Desa Karangbendo, monitoring dan evaluasi kegiatan, serta partisipasi mitra dalam proses pelaksanaan. Rangkaian kegiatan ini menghasilkan website terintegrasi yang dapat diakses oleh seluruh pihak yang berkepentingan yang berisikan informasi tentang UMKM Unggulan Desa Karangbendo baik itu produk, lokasi maupun kontak yang dapat dihubungi yang nantinya dapat meningkatkan brand awareness pada masing-masing UMKM Unggulan.