bluuebunny/crossref_metadata_2025 huggingface dataset:
Short-term efficacy of π-shaped esophageal jejunostomy in total laparoscopic radical resection of cardiac cancer and its effect on traumatic stress
Authors: Zhang Chensong , Pan Chengwu , wang Qingkang , Wang Yuanpeng , Wu Han , Ma Jiachi
Published: June 2023

Purpose
To analyze the clinical efficacy of total laparoscopic π-shaped esophageal jejunostomy and laparoscopic assisted Roux en-Y esophago-jejunostomy for cardiac cancer and their effects on traumatic stress.
Methods
We collected clinical data from 72 patients with adenocarcinoma of the esophagogastric junction who were treated in our department between June 2020 and July 2022. All patients underwent laparoscopic total gastrectomy + D2 lymphadenectomy, in whom 38 patients underwent total laparoscopic total gastrectomy with π-shaped esophageal jejunostomy and 34 patients underwent laparoscopic-assisted total gastrectomy with Roux en-Y esophago-jejunostomy. The short-term therapeutic effects, safety and effects on stress response indicators of different surgical methods were analyzed.
Results
There were no significant differences in baseline clinical and pathological data between the two groups (P > 0.05). The mean operation duration was 201.7 ± 80.3 minutes in the total endoscopic π-shaped esophageal jejunostomy group, which was longer than 166.9 ± 26.9 minutes in the laparoscopic-assisted Roux en-Y esophago-jejunostomy group (P < 0.05). The length of the surgical incision in the total endoscopic π-shaped esophageal jejunostomy group was significantly shorter, measuring 4.6 ± 2.1 cm, compared to the Roux-en-Y anastomosis group, which had an average length of 10.4 ± 2.1 cm (P < 0.01). In terms of intraoperative bleeding, the intraoperative bleeding volume of 130.3 ± 50.3 ml in the total endoscopic π-shaped esophageal jejunostomy group was significantly lower than that of 167.2 ± 72.8 ml in the laparoscopic-assisted Roux en-Y esophago-jejunostomy group (P < 0.05). Postoperative recovery time to exhaust was 3.8 ± 1.2 days in total endoscopic π-shaped esophageal jejunostomy group, significantly lower than 5.0 ± 2.0 days in laparoscopic-assisted Roux en-Y esophago-jejunostomy group (P = 0.003). In terms of postoperative extubation time, postoperative hospital stay, postoperative complications and the number of dissected lymph nodes, there were no significant differences between the total endoscopic π-shaped esophageal jejunostomy group and the laparoscopic-assisted Roux en-Y esophago-jejunostomy group (P > 0.05). In terms of stress indicators, there were no significant differences in stress indicators between the two groups before surgery, and the serum levels of CRP, cortisol (COR) and IL-6 in the π anastomosis group were significantly lower than those in the Roux en-Y esophago-jejunostomy group on postoperative days 3 and 5 (P < 0.05).
Conclusion
Total laparoscopic total gastrectomy with π-shaped esophageal jejunostomy demonstrates safety and feasibility. This surgical approach effectively reduces intraoperative bleeding, accelerates patient recovery time, minimizes postoperative pain, lowers the risk of complications, and minimally impacts the body's traumatic stress response.
Identification of COL12A1 as a novel diagnostic marker in pancreatic ductal adenocarcinoma by global proteome analysis
Authors: Qin Jiejie , Shi Minmin , Ren Lingjie , Jiang Lingxi , Shen Baiyong
Published: June 2023

Purpose: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive carcinoma without reliable non-invasive screening tests. This study aimed to identify and evaluate novel and reliable noninvasive serological biomarkers for screening PDAC.
Methods: We performed global proteome profiling of 67 PDAC tumor tissues and 67 matched normal adjacent tissues by mass spectrum to identify new biomarker in Ruijin cohort 1. This is further verified in proteome and mRNA sequencing data in published cohort by CPTAC. Next, COL12A1 and CA199 serological levels were determined in 47 PDAC sera and 75 healthy sera by enzyme immunoassay in Ruijin cohort 2.
Results: Finally, collagen type XII alpha 1 chain (COL12A1) was identified as a candidate for PDAC diagnosis in Ruijin cohort 1, and was validated to be higher in tumor tissues than the normal adjacent tissues (NATs) in CPTAC cohort. In addition, COL12A1 protein was significantly higher in case sera than control sera. The ROC analysis revealed that COL12A1 improved the performance of CA199 in discriminating PDAC from healthy individuals (AUCCA199 = 0.91 vs AUC CA199 + COL12A1 = 0.95, p < 0.05). COL12A1 also showed perfect ability to distinguish early-stage PDAC from healthy individuals (AUCCOL12A1 = 0.83), and was observed to significantly improve AUC of CA199 in stage I-II PDAC (AUCCA199 = 0.92 vs AUCCA199+COL12A1 = 0.97, p < 0.05).
Conclusion: This study reveals that COL12A1 is a potential serological diagnostic marker that complements CA199 in detecting early-stage PDAC. It is necessary for a large-scale study to validate the results.
The Effects of Mild but Chronic Stress at School on Brain Development:
A Comparative Morphometric Study Between Traditionally and Montessori-schooled Children
Authors: Schwery Patricia , Romascano David , Gómez Yasser Alemán , Messerli-Bürgy Nadine , Denervaud Solange
Published: June 2023

While many children suffer from stress due to school-related factors, some alternative schooling systems, such as the Montessori pedagogy, emphasize stress-free learning environments (e.g., no grades, no tests, peer-peer learning). This study compared brain markers of stress, i.e., hippocampus, amygdala, and medial prefrontal cortex (mPFC) volumes, as a function of school experience. A cross-sectional comparative morphometric study was run between 45 traditionally schooled children and 44 Montessori-schooled children (3-12 years). While both groups were comparable in terms of cognitive abilities, socio-economic environment, and anxiety levels, volumetric values within their hippocampus and their mPFC differed. While there was hippocampal growth across development for all participants, there was a higher gain for Montessori-schooled children. Furthermore, female traditionally schooled children showed a loss in hippocampal and mPFC volume across age, while female Montessori-schooled children showed a gain. It seems that traditional pedagogical approaches induce mild but chronic stress, affecting underlying brain structures.
Perception of space with a look at the concept of mobility and stillness in the historic houses of Tehran
Authors: Del Mohammad Sadegh Taher Tolou , Sadat Seyyedah Ashraf
Published: June 2023

Motion and stillness are necessary for architectural perception. Architectural space causes physical, visual and mental health mobility in the observer due to its mobility, fluidity and pause properties. In philosophy, the factor of motion is the basis of the perception of the truths of the material world, and journey of horizons and stillness is the basis of the perception of the truths of the spiritual world and the spiritual journey. The present study aims to perceive the space of a house by creating mobility and stillness. The present study is of qualitative analytical-descriptive type. The present study is an applied research that has been developed by descriptive-analytical method, with an emphasis on logical reasoning. At this stage, 10 houses of the Qajar period of Tehran are identified, compared, and analyzed through field observations and logical reasoning in the field of mobility and stillness. The research findings indicate that the average percentage of outdoor mobility in the spaces of historic houses in the Qajar period is 54.25% and the percentage of indoor mobility is 62.95%. The percentage of stillness in the interior of the houses is 30.55%. The results of the study show that in the houses of Qajar period of Tehran, the spaces of mobility inside the house are more than the still spaces, indicating the importance of mobility in the spaces of houses of Qajar period. The amount of outdoor mobility of the house is more than the green spaces and fountains, showing the attention to mobility, mobility and activity outside the house.
Analysis of US Airline Stock Performance using Latent Dirichlet Allocation (LDA)
Authors: Anaroua Amina Issoufou , Adhikari Hari , Choi Youngran
Published: June 2023

From changes in the interest rate to the hijacking of a commercial aircraft, there are many events that may result in a fluctuation in airline stock performance. Theimpact of US airlines’ stock performance was measured following aviation related news announcements on differing topics. The data accounted for aviation news of airlines, airports, regulations, safety, accidents, manufacturers, MRO, incidents, aviation training, general aviation, and others from Aviation Voice. A natural language processing, Latent Dirichlet Allocation (LDA), was utilized to investigate and search for patterns that can explain the movements of US airline stocks. First, the aviation related data was mined through text mining and topic modeling. Second, the LDA model approach was employed to help identify and capture certain topics mentioned in aviation voice news releases. Finally, the links between stock returns and the topics identified were investigated. The findings show that financial performance varies significantly across topics. Topics related to technology, fuel, and training positively affect the US airline stocks in the short and long terms moving average, while defense and travel cost-relatedtopics only affect the medium-term run.
Exploring Asymmetric Encryption of Harmonious-Type Labeling and Coloring Topological Coding
Authors: Zhang Xiaohui , Su Jing , Yao Bing
Published: June 2023

We use topological graphs to generate topological coding, which is a fundamental technology in number theory, algebra, and has potential application value in asymmetric encryption systems. This article proposes a method of using topological graph sequences to generate topological coding for protecting hash ciphers, which can effectively protect hash ciphers even in the event of password leakage. We use topology graphs with labelings and colorings to generate graph lattice, which is the application of graph markers in asymmetric encryption systems. There are various kinds of graph labeling, one of them is a harmonious labeling. In order to further study topological coding, we use the graph harmonious-type labelings and colorings to propose (k, d)-harmonious labelling , since they can be applied to build up a new approach of asymmetric encryption. Finally, several typical attack methods about graph lattice analyzed to verify the effectiveness of our scheme.
The post-disaster economic resilience; a study on the economic impact of flooding, and influence of cash and non-cash assistance across local and refugee population of Cox Bazar, Bangladesh
Authors: Adee Md Iltemas Amin , Lee Grace Hooi Yean , Rahman Habib
Published: June 2023

Natural disasters (i.e., flooding) exert a substantial impact on the economic activities of the poverty-stricken coastal population of Cox Bazar, Bangladesh. The economic impact of flooding is measured using individual-level data from the Cox Bazar Panel Survey (CBPS) data. Satellite data, such as the Landsat 8, the Shuttle Radar Topography Mission (SRTM) elevation data, and other resources have been used to identify the flooded areas and other geographical changes across the region. The DID results indicate flood-affected individuals had lower employment, longer work hours, and were more likely to seek jobs. However, those with jobs were found to have greater earnings. The 2SLS results indicate that cash and non-cash assistance mediate the relationship between flooding and economic outcomes. Individuals who received cash assistance were better at integrating as they had better employment rates and higher earnings. In contrast, recipients of non-cash assistance had lower employment rates and had no significant effect on earnings. In addition, the propensity score results imply that individuals with similar demographic characteristics, who have received cash assistance compared to those who did not, have lower food shortages and better health. Lastly, the triple difference estimator shows that individuals living in areas with better access to healthcare facilities had greater employment and earnings compared to those who didn’t.
Excess conductivity analysis of BiPb-2223 superconductor added with (Al2O3–15wt% ZrO2) nanopowders
Authors: aftabi a. , Mozaffari M. , Moghadam A.
Published: June 2023

Weak flux pinning and weak intergranular coupling are the main constraints of the Bi1.6Pb0.4Sr2Ca2Cu3O10+δ (BiPb-2223) superconductor that restrict its practical applications. It has been shown that introducing artificial pinning centers could enhance flux pinning capability in high-temperature superconductors. In this work, the excess conductivity analyses used to study the effects of Al2O3–15 wt% ZrO2 (AlZr) nanocomposite on the superconducting properties of the BiPb-2223 phase. A series of (BiPb-2223)1−x/(AlZr)x composite samples (0.0 wt% ≤ x ≤ 1 wt%) were synthesized. The XRD results and SEM micrographs showed that adding AlZr nanocomposite up to 0.5 wt% improves the Bi1.6Pb0.4Sr2Ca2Cu3O10+δ phase formation and intergranular coupling. The excess conductivity analyses showed that the Fermi energy EF, Fermi velocity VF, and coherence length along the c axis ξc(0) decrease with increasing the amount of the AlZr nanocomposite. the ξc(0) value decreases from 3.68 Å for AlZr free sample to 2.70 Å for x = 1.0 wt%. Moreover, different superconducting critical parameters, including lower and upper critical magnetic fields (Bc1(0) and Bc2(0)), and critical current density (Jc(0)) are estimated by the Ginsberg-Landau theory. Obtained values indicated a remarkable enhancement in the mentioned critical parameters by adding the AlZr nanocomposite. The Jc(0) value enhances from 1.4×103 A/cm2 for AlZr free sample to 3.5×103 A/cm2 for the sample with 1.0 wt% additives, which shows that the Jc(0) is improved by about 150%. The obtained values also show that the critical magnetic fields are improved by about 80% by adding the 1.0 wt% AlZr nanocomposite. The improvement of the superconducting parameters most likely attributes to the the flux pinning capability and intergranular coupling enhancment.
agenda externa governamental e o empresariado industrial brasileiro como um empreendedor político (2015–2018)
Authors: Santiago Rodrigo
Published: June 2023

Essa pesquisa insere-se no campo da análise de política externa (APE) e foca em governos e na organização de interesses setoriais, em particular, do empresariado industrial brasileiro como um empreendedor político. O espaço temporal (2015-2018) compreende um momento conturbado da vida política brasileira em que no seu segundo mandato, a presidente Dilma Rousseff sofre um processo de impeachment, e, então, é sucedida pelo vice-presidente Michel Temer. O método empregado foi o da análise de conteúdo. Conclui-se que a orientação ideológica do governo e o ativismo de grupos de interesses impactam diretamente nos rumos mais particulares da política em tela.
Delayed presentation of biopsy-proven eosinophilic myocarditis following COVID-19 mRNA vaccine
Authors: Janga Chaitra , Patel Tirth , Al Hennawi Hussam , Atam Sarin , Shah Shreeja , Naeem Ifrah , Memon Rahat , Haas Donald
Published: June 2023

Myopericarditis associated with COVID-19 mRNA vaccines has been recognized as an uncommon adverse reaction, especially among young, healthy adult males. Eosinophilic myocarditis is a rare form of inflammation reflecting a hypersensitivity reaction following an inciting event commonly caused by drugs including vaccines. Eosinophilic myocarditis, a subtype of myocarditis, is characterized by eosinophilic myocardial infiltrates. It is usually accompanied by systemic eosinophilia in the form of a drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and is rarely associated with myocyte fibrosis and/or necrosis. In this report, we present a case of biopsy-proven eosinophilic myocarditis in a 24-year-old male patient, likely secondary to COVID-19 mRNA vaccination. To our knowledge, this is the first report to describe delayed eosinophilic myocarditis following the COVID-19 mRNA vaccine. Clinicians should be aware of possible delayed presentation to avoid associated morbidity.
Spatiotemporal changes of evaporation in Golestan province based on quantile regressions
Authors: Ahmadi Sedigheh Bararkhanpour , Ghorbani Khalil , Salarijazi Meysam , Ghaleh Laleh Rezaei
Published: June 2023

The results reveal statistically significant trends with distinct slopes in distinct quantiles for each station and season so that the changes in the trend of high values (quantile 0.9) of evaporation were more than low values (quantile 0.1). In the spring, medium and high evaporation rates increased in the northern regions of the province (the highest trend slope, 0.15 mm/decade in the northeast), while they fell (with a slope of −0.15 mm/decade) in the southern regions. But the high values of evaporation in summer have increased in most of the stations (the highest trend slope, 0.15 mm/decade). In contrast, high levels of evaporation in autumn and winter grew at a rapid rate in the eastern part of the province (the highest slope according to season, 0.15 and 0.2 mm/decade), but they declined in the western half (the highest slope, −0.1 and −0.15 mm/decade, respectively). In general, there was a significant decreasing trend for evaporation, mostly in the western half, but there was an increasing trend, mostly in the eastern half of the province. Significant increases in daily evaporation, particularly during the dry season, will diminish water supplies, destabilize the agricultural sector, and eventually desertify the area.
Economic Research of Electricity Losses in PLN Due to Theft Differences with Methods Changing MCB and Influencing Measurement in kWh Meter
Authors: Utomo Teguh , Ardhenta Lunde
Published: June 2023

Today, there were many cases of theft or infringement of electricity in various ways. This was caused PLN to suffer losses due to the theft of electricity amounting to Rp 1.5 trillion per year. Electrical theft focused on kWh meter there were various kinds, such as by changing the side of the MCB and adding a needle on the kWh meter. The objective of this study were found out the recorded kWh ratio if the installation was installed normally with a modified installation by changing on the MCB side, adding a needle, and comparing the economic value that PLN should had obtained when the kWh meter was installed normally and the kWh meter was changed. The method used in the research for normal measurement  as much as 6 times the rotation of the disk and used 5 variations of load ; the measurement by changing the MCB and adding the needle was the same as the normal measurement, only when changing the MCB changes 2 A to 4 A, and when adding the needle, the disk was plugged with a needle. The result showed that the average of error difference between kWh meter that was installed normally with that has been changed on the side of MCB is 0, and kWh meter installed with normal that has been changed add needle equal to -44.1586. The difference in total cost of electricity for one month for normal kWh meter with which has been changed on the MCB side was Rp. 165.914.-, and for the normal kWh meter difference with the added needle of Rp. 58.610.
Оптические свойства золото-кремниевых структур вулканообразной формы, изготовленных с помощью фемтосекундного лазерного воздействия
Authors: Понкратова Е.Ю. , Агеев Э.И. , Жуков М.В. , Ларин А.О. , Мухин И.С. , Зуев Д.А.
Published: June 2023

Here, we experimentally study the photoluminescence of volcano-shaped hybrid structures created from a bi-layer gold-silicon film exposed by several femtosecond laser pulses at a wavelength of 1048 nm. The external and phase composition of the obtained structures were analyzed by a combination of atomic force microscopy and Raman studies. The damage threshold is found and the stability of the broadband photoluminescence of such structures is demonstrated.
Влияние содержания технического углерода на вольт-амперные характеристики полимерных композитов
Authors: Зюзин А.М. , Карпеев А.А. , Игонченкова К.Е.
Published: June 2023

The influence of the concentration (C) of technical carbon (CB) on the current-voltage characteristics (CVC) of composites based on an ethylene vinyl acetate matrix has been studied. It has been established that in polymer composites with low (С = 5%) and high (С  25%) concentrations, the conductivity is practically independent of the electric field strength. In composites with CB concentrations corresponding to the percolation region, the presence of two pronounced segments of the CVC was found. After reaching a certain threshold field, a sharp increase in conductivity was observed. The behavior of the current-voltage characteristics of such composites in the region of high fields is described with good accuracy by the Fowler-Nordheim expression.
Кинетика роста наномембран полупроводниковых соединений III-V с учетом потока реэмиссии
Authors: Дубровский В.Г.
Published: June 2023

Получено уравнение роста наномембран полупроводниковых соединений III-V на подложках с одномерными массивами полосков в оксидной маске с учетом потока реэмиссии элемента группы III. Показано, что высота наномембран увеличивается с увеличением расстояния между ними и уменьшением ширины мембран. Кинетика роста наномембран на маскированных подложках и их морфология сильно отличаются от случая адсорбирующих подложек, что необходимо учитывать при проведении ростовых экспериментов. Ключевые слова: полупроводниковые соединения III-V, наномембраны, поток реэмиссии, скорость роста, моделирование.
Определение параметров филаментов на сферическом токамаке Глобус-М2 с помощью метода допплеровского обратного рассеяния
Authors: Яшин А.Ю. , Пономаренко А.М. , Жильцов Н.С. , Кукушкин К.А. , Курскиев Г.С. , Минаев В.Б. , Петров А.В. , Петров Ю.В. , Сахаров Н.В.
Published: June 2023

In improved confinement (in H-mode) in the Globus-M2 tokamak, the development of edge-localized modes (ELMs) is accompanied by the appearance of filament structures. The use of the Doppler backscattering (DBS) method allowed to determine filament parameters both during ELMs triggered by sawtooth crashes and during independent ELMs. It is shown that the number of filaments observed during synchronized ELMs is greater and their area of observation is wider. The velocity of the filaments during all types of ELMs observed on Globus-M2 ELM is higher than on the previous tokamak Globus-M. Filaments developing immediately before an ELM burst are characterized by smaller amplitudes and velocities. Comparing the results of two diagnostic techniques, DBS and poloidal correlation Doppler reflectometry, to determine the velocity of such filaments, shows a similarity of the measured values, which may indicate linear scattering off these filaments.
Волоконно-оптический интерферометрический акселерометр горизонтального типа для сейсмоакустического мониторинга
Authors: Каменев O.Т. , Каменев А.О. , Петров Ю.С. , Подлесных А.А.
Published: June 2023

The possibility of constructing a horizontal type fiber-optic accelerometer based on a multi-turn sensing element, an optical scheme of the Mach-Zender interferometer and passive phase demodulation is shown. Laboratory tests of the accelerometer prototype were carried out. The sensitivity of the presented fiber-optic accelerometer is 1770 rad/g.
Влияние кинетики атомных ступеней на рост многокомпонентных кристаллов в условиях повышенных пересыщений
Authors: Редьков А.В. , Кукушкин С.А.
Published: June 2023

The process of growth of a multicomponent crystal at elevated supersaturations, in cases where the classical approximation of the immobility of atomic steps becomes incorrect, has been studied. Analytical expressions are derived that describe the rate of advancement of an ensemble of steps on a crystalline surface. The crystal growth rate is determined via layer-by-layer and spiral mechanisms. It is shown that the rate can differ significantly from the predictions of the classical theory of crystal growth. The results can be used to optimize the growth processes of both bulk crystals and thick epitaxial films of various multicomponent compounds and, in particular, semiconductor compounds of groups A3B5 and A2B6.
Исследование однородности распределения накачки в активном элементе в виде стержня мощных квантронов с диодной накачкой
Authors: Таривердиев С.Д. , Дракин А.Е. , Пагаев О.В. , Микаелян Г.Т. , Коромыслов А.Л. , Березуцкий А.В. , Демидчик А.И.
Published: June 2023

Experimental investigations and calculations of various optical schemes of high-power DPSS and solid-state lasers with cylindrical active elements and transverse pumping by laser diode arrays are presented. Numerical simulations were used to solve hydrodynamic problems and problems of geometric optics for DPSS with rod active elements pumping by quasi-continuous laser diode arrays. The dependencies of the uniformity of active element illumination on the geometry of the optical scheme were studied, as well as the influence of the uniformity of coolant flows over different pump arms on the uniformity of the luminescence distribution pro-file from the end of the active element. An optical pumping scheme for active element of a high-power DPSS with an optimal geometry is proposed and implemented.
Sociotechnical Challenges of Digital Health in Nursing Practice During the COVID-19 Pandemic: National Study
Authors: Livesay Karen , Petersen Sacha , Walter Ruby , Zhao Lin , Butler-Henderson Kerryn , Abdolkhani Robab
Published: June 2023

Background

The COVID-19 pandemic has accelerated the use of digital health innovations, which has greatly impacted nursing practice. However, little is known about the use of digital health services by nurses and how this has changed during the pandemic.

Objective

This study explored the sociotechnical challenges that nurses encountered in using digital health services implemented during the pandemic and, accordingly, what digital health capabilities they expect from the emerging workforce.

Methods

Five groups of nurses, including chief nursing information officers, nurses, clinical educators, nurse representatives at digital health vendor companies, and nurse representatives in government bodies across Australia were interviewed. They were asked about their experience of digital health during the pandemic, their sociotechnical challenges, and their expectations of the digital health capabilities of emerging nurses to overcome these challenges. Interviews were deductively analyzed based on 8 sociotechnical themes, including technical challenges, nurse-technology interaction, clinical content management, training and human resources, communication and workflow, internal policies and guidelines, external factors, and effectiveness assessment of digital health for postpandemic use.

Results

Sixteen participants were interviewed. Human factors and clinical workflow challenges were highly mentioned. Nurses’ lack of knowledge and involvement in digital health implementation and evaluation led to inefficient use of these technologies during the pandemic. They expected the emerging workforce to be digitally literate and actively engaged in digital health interventions beyond documentation, such as data analytics and decision-making.

Conclusions

Nurses should be involved in digital health interventions to efficiently use these technologies and provide safe and quality care. Collaborative efforts among policy makers, vendors, and clinical and academic industries can leverage digital health capabilities in the nursing workforce.
Nutrition, Obesity, and Seborrheic Dermatitis: Systematic Review (Preprint)
Authors: Woolhiser Emily , Keime Noah , Patel Arya , Weber Isaac , Adelman Madeline , Dellavalle Robert P
Published: June 2023

BACKGROUND

Pathogenesis of seborrheic dermatitis involves lipid secretion by sebaceous glands, Malassezia colonization, and an inflammatory response with skin barrier disruption. Each of these pathways could be modulated by diet, obesity, and nutritional supplements. Current treatment options provide only temporary control of the condition; thus, it is essential to recognize modifiable lifestyle factors that may play a role in determining disease severity.

OBJECTIVE

This study aimed to summarize published evidence on diet, nutritional supplements, alcohol, obesity, and micronutrients in patients with seborrheic dermatitis and to provide useful insights into areas of further research.

METHODS

A literature search of Scopus, PubMed, and MEDLINE (Ovid interface) for English language papers published between 1993 and 2023 was conducted on April 16, 2023. Case-control studies, cohort studies, and randomized controlled trials with 5 or more subjects conducted on adult participants (>14 years) were included, case reports, case series, and review papers were excluded due to insufficient level of evidence.

RESULTS

A total of 13 studies, 8 case-control, 3 cross-sectional, and 2 randomized controlled trials, involving 13,906 patients were included. Seborrheic dermatitis was correlated with significantly increased copper, manganese, iron, calcium, and magnesium concentrations and significantly lower serum zinc and vitamin D and E concentrations. Adherence to the Western diet was associated with a higher risk for seborrheic dermatitis in female patients and an increased consumption of fruit was associated with a lower risk of seborrheic dermatitis in all patients. The prebiotic Triphala improved patient satisfaction and decreased scalp sebum levels over 8 weeks. Most studies find associations between regular alcohol use and seborrheic dermatitis, but the association between BMI and obesity on seborrheic dermatitis severity and prevalence is mixed.

CONCLUSIONS

This review sheds light on specific promising areas of research that require further study, including the need for interventional studies evaluating serum zinc, vitamin D, and vitamin E supplementation for seborrheic dermatitis. The negative consequences of a Western diet, alcohol use, obesity, and the benefits of fruit consumption are well known; however, to fully understand their specific relationships to seborrheic dermatitis, further cohort or interventional studies are needed.

CLINICALTRIAL

PROSPERO CRD42023417768; https://tinyurl.com/bdcta893
A Virtual Hospital Model of Care for Low Back Pain, Back@Home: Protocol for a Hybrid Effectiveness-Implementation Type-I Study (Preprint)
Authors: Melman Alla , Teng Min Jiat , Coombs Danielle M , Li Qiang , Billot Laurent , Lung Thomas , Rogan Eileen , Marabani Mona , Hutchings Owen , Maher Chris G , Machado Gustavo C
Published: June 2023

BACKGROUND

Low back pain (LBP) was the fifth most common reason for an emergency department (ED) visit in 2020-2021 in Australia, with >145,000 presentations. A total of one-third of these patients were subsequently admitted to the hospital. The admitted patient care accounts for half of the total health care expenditure on LBP in Australia.

OBJECTIVE

The primary aim of the Back@Home study is to assess the effectiveness of a virtual hospital model of care to reduce the length of admission in people presenting to ED with musculoskeletal LBP. A secondary aim is to evaluate the acceptability and feasibility of the virtual hospital and our implementation strategy. We will also investigate rates of traditional hospital admission from the ED, representations and readmissions to the traditional hospital, demonstrate noninferiority of patient-reported outcomes, and assess cost-effectiveness of the new model.

METHODS

This is a hybrid effectiveness-implementation type-I study. To evaluate effectiveness, we plan to conduct an interrupted time-series study at 3 metropolitan hospitals in Sydney, New South Wales, Australia. Eligible patients will include those aged 16 years or older with a primary diagnosis of musculoskeletal LBP presenting to the ED. The implementation strategy includes clinician education using multimedia resources, staff champions, and an “audit and feedback” process. The implementation of “Back@Home” will be evaluated over 12 months and compared to a 48-month preimplementation period using monthly time-series trends in the average length of hospital stay as the primary outcome. We will construct a plot of the observed and expected lines of trend based on the preimplementation period. Linear segmented regression will identify changes in the level and slope of fitted lines, indicating immediate effects of the intervention, as well as effects over time. The data will be fully anonymized, with informed consent collected for patient-reported outcomes.

RESULTS

As of December 6, 2023, a total of 108 patients have been cared for through Back@Home. A total of 6 patients have completed semistructured interviews regarding their experience of virtual hospital care for nonserious back pain. All outcomes will be evaluated at 6 months (August 2023) and 12 months post implementation (February 2024).

CONCLUSIONS

This study will serve to inform ongoing care delivery and implementation strategies of a novel model of care. If found to be effective, it may be adopted by other health districts, adapting the model to their unique local contexts.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/50146
Performance Assessment of M35 and M40 Grades of Concrete Prepared using Construction and Demolition Waste
Authors: Pandey Dev Anand
Published: June 2023

Abstract: The world has, by now, identified the seriousness and challenges regarding the sustainability of resources amid major environmental concerns that are part of modern problems today. The construction industry all over the world has been explicitly using concrete owing to its quality, strength, and adaptability to various construction needs and situations. However, in the last few decades, increased awareness, legislation, and global initiatives to combat pollution, energy consumption, waste disposal, and global warming have pushed industries, researchers, engineers, and other stakeholders to substitute virgin materials with alternative construction materials. Construction and demolition account for about 30% of the total solid waste generated worldwide. The top ten countries including India and China which are contributing heavily to this waste stream, together generating about 2.5 billion metric tonnes every year. The C&D waste poses a significant strain on landfill sites, contributes to energy waste, and adds additional costs for its disposal. However, through careful sorting, processing, and recycling processes, a significant chunk of it can be reused and help minimise environmental impact. The work presented here involves fractional replacement of C&D waste aggregates viz., RCA and RA in amounts ranging from 05-25% as coarse and fine aggregates, respectively. Most of the previous works have not aimed at higher grades like M35 and M40, which form the subject matter of this paper. Several tests were conducted to estimate the fresh and hardened state properties of concrete, most important being compressive and tensile strength as well as slump test for workability.
Comparative Analysis of Machine Learning and Deep Learning Techniques for Intrusion Detection
Authors: Reddy K. Teja
Published: June 2023

Abstract: This comparative analysis examines the application of both machine learning and deep learning methods in network traffic classification. Network traffic classification holds significant importance in network security, traffic management, and Quality of Service provisioning. The analysis covers a range of popular machine learning techniques, such as Decision Tree, KNearest Neighbours, Naive Bayes, Logistic Regression, Multi-Layer Perceptron, and Feed Forward Neural Network with a sigmoid activation function. Each technique's strengths and weaknesses are discussed, along with the factors that influence the selection of a particular technique. Ultimately, the choice of machine learning approach depends on data characteristics, performance requirements, and available resources. The demand for prompt and accurate classification of Internet traffic has been steadily increasing, driven by the emergence of new applications in the field. Traditional approaches based on port numbers and packet payloads have become insufficient, prompting the adoption of pattern recognition techniques that leverage statistical flow-based features in training samples to classify unknown flows. To ensure real-time identification of traffic types, the chosen method must be capable of swift classification before the entire flow is completed. In this study, a supervised machine learning approach and deep learning techniques are proposed for the identification of various Internet applications. The proposed system exhibits the ability to detect application types based on just a few initial packets within each flow, enabling realtime operation. Promising results were achieved, with the Logistic Regression algorithm attaining the highest accuracy of 80.7%.
Mitigating Air Pollution in Indian Cities with the Use of Bio Facades
Authors: Singh Ar. Rashmi
Published: June 2023

Abstract: Today, the biggest issues facing the planet are air pollution and, as a result, global warming. These problems may affect the climate, human health. To mitigate air pollution frequently concentrate on reducing the sources of the pollutants. This approach can significantly lower the amount of new air pollutants, but it has little impact on the air's already-existing contaminants. By recognizing the current situation, this study seeks to limit the level of harm to humans by regulating air pollution through municipal engineering, facade structures, and architectural design. The air quality of the urban environment can be significantly influenced by the façades of buildings. The ability of nature to manage air pollution has been used to the realm of architecture. Therefore, this study compares three different forms of bio-façades (namely, Water façade, Green façade, and Microalgae) by utilizing nature's capacity to manage carbon dioxide. These facades do not harm human health and do not require any special technology. . Then, after identifying the aforementioned biological façade kinds, we compared their strength and weaknesses, cost, environmental stability and chose the best one. Which façade system is best according to Delhi and luck now’s air pollution condition. Purpose: The goal of this study is to gain a better understanding of how can we improve air quality and reduce pollutants with the help of bio facade.
Formulation and Evaluation of Sustained Release Matrix Tablet Metformin Hydrochloride
Authors: Mhaske Padmaja K.
Published: June 2023

Abstract: The present study outlines a systematic approach for designing and development of Metformin Hydrochloride sustained release matrix tablets. Different formulations were formulated by wet granulation technique using Xanthan gum and HPMC K100M as polymers along with other excipients The formulations were evaluated for their physicochemical properties.
Faktor-Faktor yang Berhubungan dengan Minat Masyarakat Berkunjung ke Pelayanan Kesehatan Selama Covid-19 di Kota Tangerang Selatan Tahun 2020
Authors: Sari Ranita Darma , Fajrini Fini , Latifah Moor , Suherman
Published: June 2023

ABSTRAK

Awal tahun 2020, dunia telah digemparkan dengan adanya virus baru yaitu corona virus dengan jenis baru (SARS-CoV-2) disebut Corona virus disease 2019 (COVID-19). Mengakses layanan medis secara jarak jauh dengan konsultasi dokter atau tenaga kesehatan untuk memastikan keberlanjutan perawatanyang dibutuhkan dan mempertimbangkan jika jadwalnya dapat ditunda sehingga dapat menyebabkan minat kunjungan ke pelayanan seperti Puskesmas, klinik dan Rumah Sakit berkurang. Tujuan penelitian ini adalah untuk diketahuinya faktor – faktor yang berhubungan dengan minat masyarakat berkunjungke pelayanan kesehatan selama COVID-19 di Kota Tangerang Selatan Tahun 2020. Penelitian ini merupakan penelitian deskriptif kuantitatif yang bersifat cross sectional, sebanyak 100 sampel diambil dengan menggunakanteknik probability sampling dengan simple random sampling. Hasil penelitian ditemukan variabel yang berhubungan dengan minat masyarakat yaitu, pengetahuan (p value = 0,005) dan sikap (p value = 0,005),sedangkan fasilitas (p value = 0,668) dan petugas (p value = 1,000). Perlu meningkatkan informasi mengenai COVID-19 maupun mengenai pelayanan kesehatan COVID-19 agar pengetahuan masyarakat baik dan tidak menyebabkan kepercayaan terhadap isu yang tidak benar di masyarakat.

Kata Kunci: Fasilitas, Minat Masyarakat, Petugas, Pengetahuan dan Sikap
Hubungan Karakteristik Sosial Ekonomi dan Keterpaparan Informasi Kesehatan dengan Penerimaan Vaksinasi Covid-19 pada Masyarakat di Kecamatan Medan Tuntungan
Authors: Manalu Sarah Patumona , Nurfahasdi Meutia , Rahayu Silda Adi , Nadhira Ade Citra
Published: June 2023

Covid-19 vaccination is one of the efforts to strengthen the body's resistance to the disease. The purpose of this study was to analyze the relationship between socio-economic characteristics and exposure to health information with the acceptance of covid-19 vaccination in the community in Medan Tuntungan District. This research is a cross sectional survey research. The population of people aged over 18 years in Medan Tuntungan District is 68,000 people. The data is analyzed by using univariate and bivariate analysis. The results of the study are that there is a relationship between sources of information about covid-19 and education (p-value 0.000), there is a relationship between sources of information and work (p-value 0.000), there is a relationship between work and vaccine status (p-value 0.040), there is a relationship between education and the incidence of infection ( p-value 0.001), there is a relationship between education and owned health insurance (p-value 0.000), and there is a relationship between work and owned health insurance (p-value 0.000). The conclusion is there is a relationship between the level of education, work, and information exposure with the receipt of the covid-19 vaccination in the Medan Tuntungan District.
KARSLI ÂŞIKLARIN İCRALARINDA KULLANDIKLARI ÂŞIK HAVALARININ TÜRK MÜZİĞİ MAKAM DİZİLERİ BAKIMINDAN DEĞERLENDİRİLMESİ
Authors: PELİKOĞLU Mehmet Can , ACAY Ferhat
Published: June 2023

Bu çalışma geçmişten günümüze çeşitli değişimlere uğrayarak varlığını sürdürmeyi başarmış olan âşıklık geleneğini ve bünyesindeki âşık havalarının Türk müziğiyle yakınlık durumunu konu edinmektedir. Çalışmada örneklem olarak geleneğin yoğun bir şekilde yaşatıldığı Kars ili ele alınmış ve ildeki âşık havalarının isimleri tespit edilmeye çalışılmıştır. Buradan hareketle yüz yüze ve telefon ile görüşmeyi kabul eden 7 Karslı âşıkla görüşmeler yapılmış, âşık havalarıyla ilgili sorulan sorulara cevaplar aranmaya çalışılmıştır.
Araştırma sürecinde konuya ilişkin kaynak taraması yapılmış ve kişisel görüşme tekniği kullanılmıştır. Çalışmanın akışında Kars ili âşıklık geleneği, makam, hava ve benzer anlamda kullanılan ayak terimi ile konuya ilişkin diğer kuramsal bilgilere yer verilmiştir. Karslı âşıkların bilgi ve görüşlerinden faydalanılarak edinilen bulgular değerlendirilmeye çalışılmıştır.
Elde edilen bulgular ışığında, görüşme yapılan Karslı âşıkların icralarında kullandıkları 126 hava ismine ulaşılmış ancak bir kısmının ezgisine ulaşılamamıştır. Bu hava isimlerinden ezgisine ulaşılan âşık havalarının icraları incelenmiş ve Türk müziği makam dizileriyle yakınlık yönünden değerlendirilmiştir. Tespit edilen âşık havalarının; Türk müziği makam dizilerinden en çok Segâh makamına, en az ise Rast ve Hicaz makamlarına yakınlık gösterdiği ve âşık meclislerinde bir icra sıralaması ritüelinin olduğu sonuçlarına ulaşılmıştır.
Drinking Establishments in the Novel Crime and Punishment. An Artistic Detail in the Legal Field of the Drinking Reform of 1861
Authors: Dekhanova Olga A.
Published: June 2023

By the middle of the 19th century, the theme of drunkenness as the cause of the most heinous vices and crimes had become one of the most discussed. Numerous abuses by the owners of drinking establishments led to a spontaneous manifestation of people’s sobriety in the late 50s of the 19th century. This caused significant damage to the state budget. The result of this confrontation was the introduction of a new government policy on drink sales. The terminological replacement of “kabak” with drinking house gradually replaced this name from everyday language but retained its historically negative reputation in the public mind. By the middle of the 19th century, the use of the lexeme “kabak” in the literary language already had a distinct metaphorical meaning. The “kabak”, as the main culprit of drunkenness and depravity, became the embodiment of social evil, and the problem of drunkenness was realized as a religious opposition “righteousness — sin.” The action of the novel Crime and Punishment takes place in the period of the first consequences of the new drinking reform. One of the features of the novel is Dostoevsky’s use of the lexeme “raspivochnaia” as an everyday colloquial name for a drinking house, carrying a pronounced emotional reaction of social rejection. “Raspivochnaia” is a thorough leitmotif of the story. It is an element of the general negative atmosphere of the city along with stuffiness, the smell of dust, lime, and slop. It is associated with descriptions of the psychological state of Raskolnikov. The mention of it accompanies all significant events and meetings for the characters. But the most important thing is its connection with the religious and moral problems of choice, with the inevitability of the fall into sin or the possibility of resurrection. This emotional and semantic image, which determines the further narrative, is built by Dostoevsky already at the very beginning of the novel, in the tavern where Marmeladov and Raskolnikov meet.
Schiller’s Motifs in Crime and Punishment by Fyodor Dostoevsky
Authors:   Lomonosov Moscow State University, Krinitsyn Aleksandr B.
Published: June 2023

Friedrich Schiller was one of the most important Western authors for Dostoevsky. The importance lay both in being inspired by Schiller’s ideas and their creative development, and in direct controversy to the point of ironic criticism. In the novel Crime and Punishment frequent appeals to Schiller are not followed by precise quotations or recognizable allusions, and as a result they require decoding and commenting. This article attempts to do this. The influence of Schiller’s heritage in the novel can be traced on different levels: common ideological motives (the polemic with the concept of schöne Seele; a theodicy based on the philosophical concepts of love and beauty); aesthetic positions (an aestheticization of suffering and crime as “sublime”); anthropology (the creation of an ideological hero; the judgment about the deep disharmony in the nature of the contemporary man, which leads to an unlimited “largeness of the soul” to the point of a terrible moral ambivalence), and innovative methods of psychologism (a depiction of a criminal’s psychology from the inside, with an effect of empathy). Of particular importance for the ideological content of the novel Crime and Punishment was Schiller’s drama The Robbers; in terms of psychological analysis, the dramatic passages of The Misanthrope and the story The Criminal of Lost Honour also played a significant role. The latter are first introduced in academic commentary on Dostoevsky’s novel.