bluuebunny/crossref_metadata_2025 huggingface dataset:
Extracellular Vesicles Derived from Metastatic Melanoma Cells Transfer α7-nAChR mRNA, Thus Increasing the Surface Expression of the Receptor and Stimulating the Growth of Normal Keratinocytes
Authors: Bychkov Maksim L. , Kirichenko Artem V. , Mikhaylova Irina N. , Paramonov Alexander S. , Kirpichnikov Mikhail P. , Shulepko Mikhail A. , Lyukmanova Ekatherine N.
Published: October 2022

We have previously shown that extracellular vesicles secreted by metastatic melanoma cells stimulate the growth, migration, and stemness of normal keratinocytes. This study showed for the first time that extracellular vesicles secreted by the metastatic melanoma cell lines mel H, mel Kor, and mel P contain, both at the mRNA and protein levels, the 7-type nicotinic acetylcholine receptor (7-nAChR), which is involved in the regulation of the oncogenic signaling pathways in epithelial cells. Incubation with the vesicles secreted by mel H cells and containing the highest amount of mRNA coding 7-nAChR increased the surface expression of 7-nAChR in normal Het-1A keratinocytes and stimulated their growth. Meanwhile, both of these effects disappeared in the presence of -bungarotoxin, an 7-nAChR inhibitor. A bioinformatic analysis revealed a correlation between the increased expression of the CHRNA7 gene coding 7-nAChR in patients with metastatic melanoma and a poor survival prognosis. Therefore, extracellular vesicles derived from metastatic melanoma cells can transfer mRNA coding 7-nAChR, thus enhancing the surface expression of this receptor and stimulating the growth of normal keratinocytes. Targeting of 7-nAChR may become a new strategy for controlling the malignant transformation of keratinocytes.
Risk Management Within the Framework of the Concept of Sustainable Development
Authors: Trifonov Yu. V. , Brykalov S. M. , Trifonov V. Yu.
Published: October 2022

The issues related to the transformation of risk management subsystems within the framework of the concept of sustainable development in companies, enterprises, firms and organizations are considered. The ways of solving problems aimed at the formation of separate subsystems of riskmanagement, within which the concept of sustainable development is fully taken into account, are proposed. Th e variants of embedding such subsystems into existing management systems are analyzed.The goal-setting procedures of companies are proposed, coordinated with the principles of sustainable development and taking into account social, environmental and other risks. The analyzed goals are divided into four groups. Relevant risks are identifi ed, identifi ed and described for each of the groups. It is noted that there is a need for careful regulation of the processes of creating and reformatting risk management subsystems, taking into account compliance with the principles of sustainable development. The proposed methods for the formation of risk management subsystems are partially illustrated by the example of a large company that is part of the Rosatom State Corporation.
The Main Directions of Transformation of the Resource Provision of the Risk Management System of the Organization
Authors: Pankrukhina A. M. , Syunyakova V. R. , Kapustina N. V.
Published: October 2022

In the conditions of uncertainty of doing business, special importance is attached to the risk management of the organization. Effective risk management is impossible without competent resource support of the risk management system. In turn, the rational allocation of the organization’s resource potential is also impossible without a risk management system. The instability of the external environment constantly generates new risks, and to manage them, it is necessary to transform the resource complex of the organization in accordance with new trends.

   Identification of such trends that can signifi cantly change the approach to the resource provision of the risk management system is the purpose of this work.

   Approaches to the defi nition of such basic concepts as “risk” and “resource potential” were considered, diff erences in the main standards in the field of risk management on the issue of risk management stages were described. Also, the need to create and take into account recommendations on the side of the risk management system when making decisions, in particular, the use of a risk-based approach when using resource potential, was justifi ed. In addition, three main trends in the development of modern business were identifi ed: the strengthening of the infl uence of geopolitical risks, business consolidation and the introduction of the concept of sustainable development based on ESG principles. Th e key risks were identifi ed, the appearance of which may become or has already become a consequence of the above-mentioned directions of business transformation, and the necessary resource support for the implementation of measures to manage these risks was described.
METHODOLOGICAL APPROACHES TO THE FORMATION OF THE RATING OF THE CONSTITUENT ENTITIES OF THE RUSSIAN FEDERATION, REFLECTING THE EFFICIENCY AND QUALITY OF MEDICAL CARE BY PROFILE
Authors: Mikhailov I. A. , Omelyanovsky V. V. , Samsonova E. S. , Kusakina V. O. , Lebedenko G. G.
Published: October 2022

Aim of the study - determination of approaches to the formation of the rating of the constituent entities of the Russian Federation, reflecting the state of medical care in various profiles (the effectiveness and quality of medical care in various profiles). The study included a comprehensive analysis of the structure and content of the reports based on the results of national medical research centers field events using classification and grouping methods. Assessment of the advantages and disadvantages of the used variants of the methodology for forming the subject rating of the Russian Federation used the method of selective SWOT analysis of methodologies published in the form of scientific articles. Further, based on the results obtained, the main requirements for building a rating system for subjects of the Russian Federation based on the indicators of efficiency (performance) and the quality of medical care were formulated. The possibility of applying international experience in building benchmarking systems in the Russian Federation is analyzed and requirements are formulated for building a subject rating system of the Russian Federation, taking into account the peculiarities of the domestic healthcare system. There are 3 main methodological approaches to the formation of the subject rating of the Russian Federation: a quantitative score rating assessment of quantitative indicators without weight coefficients, a qualitative rating assessment of the effectiveness of medical care in a profile without weight coefficients, and a mixed score-rating assessment of quantitative and qualitative indicators using weight coefficients determined only by an expert method. It has been established that many of the existing approaches to the formation of the subject rating of the Russian Federation are based on a combination of a point rating and weight coefficients established by an expert method. Since different indicators have different contributions to the final integral value of the subject rating of the Russian Federation, it is advisable to conduct another study to establish weight coefficients for indicators.
NORMATIVE AND LEGAL ASPECTS OF THE FORMATION OF THE BASIC PREREQUISITES OF PUBLIC HEALTH (PUBLICATIONS REVIEW)
Authors: Kirshchina I. A. , Shestakova T. V. , Soloninina A. V. , Krasheninnikov A. E. , Habriev R. U.
Published: October 2022

Preservation of public health is the main goal of social progress and development of the society. The search for potential opportunities to improve individual and public health indicators is a positive predictor of increasing the socio-economic efficiency of the society and increasing the healthy life expectancy of citizens. The scientific review provides arguments in favor of the need for professional collaboration of specialists from various industries in order to universally realize the most important right of citizens to protect their own and public health. Regulatory legal documents defining national and international policy in the field of health protection and forming the general vector of development of health care activities were used as the sources of information for the formation of the basis of the study. As a result of a logical generalization of global and national priorities and trends in the development of the healthcare sector, the main prerequisites (determinants) of health saving of citizens, adopted by the world community and reflected in domestic documents, are formulated. The main prerequisites (determinants) of health are defined as: promotion of activities that advantage health protection; creation of a single preventive space; specification of the concept of 'responsible attitude to health'; coverage of the entire life cycle of a person and all spheres of his activity in the formation of a responsible attitude to health and motivation for its preservation; development of information technologies in the field of health protection; expansion of intersectoral and interdisciplinary cooperation in order to maintain and strengthen health; improvement of public health literacy; transformation of health services from the standpoint of health protection; development of human resources to ensure health-saving activities. The identified determinants of the preservation of individual and public health can act as a theoretical basis for the development of a scientific and practical methodology aimed at solving problems of improving health through the potential of interdisciplinary interaction of specialists in various fields of activity.
DETERMINANTS OF QUALITY OF LIFE AND MORBIDITY IN THE ADULT POPULATION
Authors: Bakirova E. A. , Galiullin D. A. , Shulaev A. V. , Kitaeva E. A , Galiullin A. N.
Published: October 2022

In the Russian Federation, the number of working-age population is growing annually: in 2014, the number of able-bodied population was 33.8 million people(23.5%), while in 2018 this figure increased to 37.3 million (25.9%) [6]. In the Republic of Tatarstan, at the beginning of 2019 the number of able-bodied citizens reached 986 thousand people(26.0%). The purpose of this study was to analyze the determinants of the adult living standarts and the impact of these determinants on morbidity rates. A survey of 897 people using the SF-36 international questionnaire 'SF-36 Health Status Survey'. The majority of the working-age population under study was aged 60-64 (30%) and 65-69 (26%), aged 55-59 and 70-74 were 12% and 18% respectively. The smallest number of those under study was aged 75-79 (8%) and 80 and older (6%). Thus, our research has shown that the living standarts of over working-age population living in a large metropolis tends to significantly decrease depending on the age and gender. There was discovered a high level of prevalence of medical and social risk factors in these individuals, which are involved in the formation of the determinant of living standarts. For the first time, it was revealed that in people over the working age, the intensity of morbidity depends on the level of determinants of living standarts. The data obtained make it possible to develop measures to improve the quality of life of people over the working age and reduce their morbidity.
EPIDEMIOLOGICAL FEATURES OF PAPILLOMAVIRUS INFECTIONS AND CERVICAL CANCER IN THE REPUBLIC OF BASHKORTOSTAN AND THE KALININGRAD REGION
Authors: Olkov I. G. , Kononova I. N. , Grishina N. K. , Dobrokhotova Yu. E.
Published: October 2022

In the context of improving cancer prevention programs, it becomes relevant to justify the introduction of regional HPV cervical cancer screening programs based on a study of the prevalence of human papillomavirus infection and cervical cancer.Aim: to identify the main patterns of the prevalence of human papillomavirus infection and cervical cancer in Bashkortostan and the Kaliningrad region for the scientific substantiation of the criteria for the adoption of regional screening programs.A prospective analytical cohort single-stage observational examination of 3428 women of the Republic of Bashkortostan and 1246 women of the Kaliningrad region was carried out, as well as a retrospective observational analytical study of cervical cancer incidence in Bashkiria and the Kaliningrad region according to the official statistics from 2011 to 2020 compared to Russian indicators.In Bashkortostan and the Kaliningrad region, HPV DNA was detected in 48.7% and 54.2% of women of reproductive age, respectively, of which HPV of high oncogenic risk (HPV HR) was 51.7 ± 6.2%, and 23.4% were found to have PCM . In the Kaliningrad region, HPV DNA was detected in 47.2% of the women under study, HPV VR - 31.1%, in 25.5% accompanied by cervix uteri diseases. An increase in the incidence is noted in the Kaliningrad region by 38.6% over 10 years, with an annual increase of 3.8%. In Bashkortostan, the growth is demonstrated by 31.8% with an annual increase of 3%, which is significantly higher than in the Russian Federation (13.3%, р=0.001). For 10 years, the prevalence of cervical cancer has increased in the Kaliningrad region by 10.1%, with an average annual increase of 1.1%. In Bashkortostan, the prevalence of CSM increased by 4.7% with an annual increase of 0.3%.The high prevalence of HPV infection among women of reproductive age, the unfavorable dynamics of indicators of cervical HPV-associated oncopathology in remote regions of the Russian Federation (Bashkiria and the Kaliningrad region) is a scientifically based criterion for the reorganization of regional cervical screening programs. The implementation of Organized screening with primary HPV examination with mandatory separate genotyping of types 16 and 18 and the remaining 12 types of HPV HRC in a complex will enhance the effectiveness of ongoing preventive measures and meet international standards.
TOPICAL ISSUES OF MEDICAL REHABILITATION OF PATIENTS WITH THE CONSEQUENCES OF SEVERE TRAUMATIC BRAIN INJURY AT THE MUNICIPAL LEVEL
Authors: Sereda A. N. , Achkasov E. E. , Memetova A. S. , Kim V. V.
Published: October 2022

The article presents the age-sex structure of people who have suffered severe traumatic brain injury on the example of a municipal medical organization providing medical care and medical rehabilitation in outpatient settings. The high prevalence of this type of injury among males of working age has been established. The duration of temporary disability and the timing of referral of this category of people for medical and social examination are reflected. There is a high level of disability among people who have suffered severe traumatic brain injury, and in most cases they are assigned more severe first and second disability groups. The article reflects the personnel problems of a municipal medical organization providing outpatient medical care in the formation of a multidisciplinary rehabilitation team, which require their resolution at the regional level.
RESEARCH OF PROBLEMS OF MEDICAL AND SOCIAL WORK IN THE RUSSIAN FEDERATION (REVIEW OF DISSERTATIONS)
Authors: Martynenko A. V.
Published: October 2022

The development of social work in the field of health protection (medical and social work) largely depends on the ongoing scientific research on this topic. The review presents an analysis of dissertations, which demonstrate research on various aspects of medical and social work as a professional activity. The analyzed studies cover a 25-year period from the beginning of the first dissertation work in this area. Dissertations were carried out within the framework of medical, sociological and pedagogical sciences, it is based on the interdisciplinary approach in the formation of the modern system of social work in the Russian Federation.
Medical and economic analysis of the effectiveness of the structural units of a medical organization
Authors: Marisov L. V. , Kobyatskaya E. E. , Butareva M. M. , Metsger A. V.
Published: October 2022

Medico-economic analysis in a medical organization is a set of techniques and methods for assessing the indicators of medical, industrial and financial activities, the purpose of which is to choose ways to rationally use internal resources. The main objectives of medical and economic analysis is to determine the reserves for the use of the organization's resources; introduction of effective technologies of the treatment process; assessment of the effectiveness of medical care, assessment of the effectiveness of management decisions. The combination of types of analysis, their subordination to management goals can improve the efficiency of the medical organization and its structural divisions.In the context of increasing competition in the medical services market, the importance of medical and economic analysis in medical organizations of various forms of ownership is growing. State medical institutions are no exception. Modern autonomous and budgetary healthcare institutions operate in the status of independent economic entities, while the role of the chief physician as the organizer of the medical and economic process, as well as the role of the head of the structural unit, who must analyze the results and costs, calculate the need for material and financial resources, determine efficiency of medical activity.The subject of the analysis of this article is to determine the optimal algorithm for conducting a medical and economic analysis in the context of the functioning of the structural units of a medical organization.
IMPROVING THE ORGANIZATION OF LABOR AND THE QUALITY OF MEDICAL CARE AT PARAMEDIC AND OBSTETRIC STATIONS
Authors: Gadzhiev R. S. , Agalarova L. S. , Ragimov G. G.
Published: October 2022

In the provision of primary health care to the rural population, the role of paramedic and obstetric stations (FAP) is great.The purpose of the study is to develop a system of measures aimed at improving the quality of medical care provided at paramedic and obstetric stations. The study was conducted in 2019-2020 on the basis of 26 FAP of 12 central district hospitals (CRH) of the Republic of Dagestan. The organization of labor of 26 paramedics and 26 midwives during 1740 hours was studied by the method of time-lapse observation. The content of 16511 visits by the FAP population was analyzed. The expert evaluation method studied the quality of medical care to 445 patients on 7 FAP. The main work of FAP paramedics accounts for 74.5%, and for midwives - 76.3% of all labor costs. A significant share in the cost structure is occupied by preventive (22.9% for paramedics and 27.8% for midwives) and diagnostic and therapeutic activities (17% and 15.6%). There are high costs for transitions and relocations (17.3% and 14.1%) and for working with documentation (13.7% and 14.5%). In the structure of visits by the population of paramedics and midwives of FAP, for reasons of the greatest proportion are visits with therapeutic and diagnostic purposes (37%), followed by visits for medical appointments (32.8%) and preventive (23.9%). The quality of medical care provided by paramedics to patients with therapeutic diseases was inadequate in 23.8% of cases. Every third (35.7%) patient was treated with FAP unreasonably. Out of the total number of patients who were treated unreasonably on FAP, according to experts, 62.5% had to be treated in the CRH, 34.8% - in the district hospital (outpatient clinic).
ISSUES ON EDUCATION OF CHILDREN IN LONG-TERM MEDICAL NEEDS IN HEALTHCARE ORGANIZATIONS
Authors: Besschetnova O. V. , Volkova O. A. , Aliev Sh. I.
Published: October 2022

The article presents a theoretical analysis of domestic and foreign experience in teaching children undergoing long-term treatment or rehabilitation in the context of medical care. The specification of educational process, its differences from the traditional classroom-lesson system, the main role of stakeholders such as administration and medical organization, teachers, children and parents and different educational technologies, as well as the basic functions of the education of children in a hospital school are analyzed.
TRAINING OF GROUP MODEL CLINIC SUPERVISION IN DOCUMENTATION OF NURSING CARE AT SANSANI HOSPITAL, PEKANBARU
Authors: Mayenti Fitra , Meri Dilgu , Redho Ahmad , Deswita Deswita
Published: October 2022

Documentation of nursing care is the responsibility of nurses in improving the quality of nursing services. Nursing documentation is an indicator of quality in assessing the quality of services provided by nurses. Good supervision can improve the competence and performance of nurses in the room. Supervision is a manager's professional support in providing assistance and direction to nursing staff to develop their abilities and competencies of nursing staff. Sansani Hospital in documenting care has made a policy that the application of nursing care documentation is according to standards, but the implementation is still not up to standard. The implementation of supervision in the documentation by the supervisor has not been optimal. Therefore, the IbM team will conduct clinical supervision training for the model group in documenting nursing care. IbM is carried out for 1 year, while the targets in this IbM are the head of the room and the team leader at Sansani Hospital. The solutions offered are socialization of clinical supervision and documentation of nursing care and simulation of the implementation of group model clinical supervision. IbM's output target is clinical supervision training on a group model in nursing care documentation developed in the form of modules and publications in online media. After the training, it was found that there was an increase in knowledge about the supervision of the model group in the documentation of nursing care.
DIGITALIZATION OF THE TSANAWIYAH MADRASAH EDUCATION PROCESS IN CIMACAN DISTRICT, CIANJUR REGENCY IN SUPPORTING SMART VILLAGES
Authors: Khaerudin Muhammad , Ramdhani M Asep , Prasetyo Adityo Budi
Published: October 2022

The strong current of globalization has driven advances in technology, information and communication which then brought and forced changes in governance for various sectors, ranging from education, business to government. Communication technology is seen as capable of acting as an effective and efficient solution to a problem. One of the main phenomena of this technological advancement is the emergence of the Industrial Revolution 4.0. The Industrial Revolution 4.0 is marked by the widespread use of the internet, with sensors that are getting smaller, stronger and cheaper. School Digitization is an implementation of new learning, which is prepared to face the industrial revolution 4.0. The characteristics of the new learning are student-centered, use multimedia, prioritize collaborative work, exchange information, and encourage critical thinking and problem solving. Students do not only learn in conventional ways by listening to lectures from teachers and reading textbooks. However, they are challenged to collect relevant information, collaborate with friends, and solve problems from the problems they face and present them.
Body surface distribution of T wave alternans is modulated by heart rate and ventricular activation sequence in patients with cardiomyopathy
Authors: Ghoraani Behnaz , Suszko Adrian M. , Selvaraj Raja J. , Subramanian Anandaraja , Krishnan Sridhar , Chauhan Vijay S.
Published: October 2022

Background

T wave alternans (TWA) is an electrocardiographic marker of heightened sudden death risk from ventricular tachyarrhythmias in patients with cardiomyopathy. TWA is evaluated from the 12-lead electrocardiogram, Frank lead, or Holter lead recordings, however these clinical lead configurations will not record TWA from adjacent regions of the body torso.

Objective

We tested the hypothesis that changing heart rate or ventricular activation may alter the body surface distribution of TWA such that the clinical ECG leads fail to detect TWA in some patients; thereby producing a false-negative test.

Methods 

In 28 cardiomyopathy patients (left ventricular ejection fraction 28±6%), 114 unipolar electrograms were recorded across the body torso during incremental atrial pacing, followed by atrioventricular pacing at 100, 110 and 120bpm. TWA was measured from each unipolar electrogram using the spectral method. A clinically positive TWA test was defined as TWA magnitude (Valt) ≥1.9 uV with k ≥3 at ≤ 110bpm.

Results 

Maximum Valt (TWAmax) was greater from the body torso than clinical leads during atrial (p<0.005) and atrioventricular pacing (p<0.005). TWAmax was most prevalent in the right lower chest with atrial pacing 100 bpm and shifted to the left lower chest at 120 bpm. TWAmax was most prevalent in left lower chest with atrioventricular pacing at 100 bpm and shifted to the left upper chest at 120 bpm. Using the body torso as a gold standard, the false-negative rate for clinically positive TWA with clinical leads was 21% during atrial and 11% duringatrioventricular pacing. Due to TWA signal migration outside the clinical leads, clinically positive TWA became false-negative when pacing mode was switched (atrial->atrioventricular pacing) in 21% of patients.

Conclusions

The body surface distribution of TWA is modulated by heart rate and the sequence of ventricular activation in patients with cardiomyopathy, which can give rise to modest false-negative TWA signal detection using standard clinical leads
Same-Day Use of Cigarettes, Alcohol, and Cannabis Among Sexual Minority and Heterosexual Young Adult Smokers
Authors: Nguyen Nhung , McQuoid Julia , B. Neilands Torsten , Dermody Sarah , Holmes Louisa M. , Ling Pamela M , Thrul Johannes
Published: October 2022

Objective: Sexual minority (SM) young adults have higher rates of substance use than heterosexuals, but little is

known about daily use of multiple substances, which confer numerous health risks for this population. Using daily

diary data from a smartphone-based study, we examined the associations between sexual identity (i.e., SM vs.

heterosexual) and patterns of same-day multiple substance use (i.e., cigarettes and alcohol, cigarettes and cannabis,

alcohol and cannabis, and all 3 substances). Method: Young adult smokers (N  147, aged 18–26, 51.7% female,

41.5% SM, 40.8% White) reported consecutive daily assessments on substance use over 30 days. We used

generalized estimating equations to examine associations between sexual identity and patterns of same-day multiple

substance use, controlling for demographic factors and psychological distress. Results: Of 2,891 daily assessments,

16.7% reported same-day use of cigarettes and alcohol, 18.1% cigarettes and cannabis, 1.5% alcohol and cannabis,

and 15.0% use of all 3 substances. SM participants (vs. heterosexuals) had significantly greater odds of reporting

days with use of cigarettes and cannabis [Adjusted Odds Ratio (AOR)  2.05, 95% Confidence Interval (CI) [1.04,

4.01]] and use of all three substances (AOR  2.79, 95% CI [1.51, 5.14]) than days with single substance use or

no use. Conclusions: These findings warrant tailored interventions addressing multiple substance use among SM

young adults and temporally accurate measures of multiple substance use patterns.
Behavioral plasticity allows ungulates to balance risk and reward following megafire
Authors: Calhoun Kendall , Connor Thomas , Gaynor Kaitlyn , Van Scoyoc Amy , McInturff Alex , Kreling Samantha , Brashares Justin
Published: October 2022

Anthropogenic climate and land use change has accelerated the frequency of extreme climatic disturbances such as megafire. These megafires dramatically alter ecosystems and threaten the long-term conservation of economically and ecologically important species, including native ungulates. Recent work suggests that ungulate species may be able to adjust to the immediate effects of megafire by adjusting their movement and behavior, but whether these adjustments persist or change over time following these major disturbances is far less is understood. We take advantage of a rare research opportunity to examine how a dominant ungulate species, black-tailed deer (Odocoileus hemionus columbianus), adjusts its movement and behavior immediately following a megafire. We collected GPS data from 24 individual doe over the course of a year and fit these data to resource selection functions (RSFs) and hidden Markov movement models (HMMs) to assess whether and how deer alter habitat selection and behavioral decisions to adjust to novel landscape conditions following this megafire. We found compelling evidence of adaptive capacity across black-tailed deer following megafire, with deer modifying their habitat usage and behavior following megafire. Deer avoided exposed (chaparral) and severely burned areas immediately following megafire, but later altered these behaviors to eventually select for areas that burned at higher severities to potentially take advantage of enhanced forage in these recovering areas. These results suggest that despite their high site fidelity, this deer population, and similar ungulate species, can effectively navigate altered landscapes to track relatively sudden shifts in predation risk and resource availability. The successful adjustment of dominant ungulate species to extreme disturbances such as these could help facilitate resilience at broader ecological and trophic scales.
THE IMAGE OF HRYHORII SKOVORODA IN POETIC INTERPRETATIONS BY PAVLO TYCHYNA AND VASYL STUS
Authors: Havryliuk Nadiia
Published: October 2022

The comparison of works by P. Tychyna and V. Stus allows us not only to see the common and different in the interpretation of Hryhorii Skovoroda (comparative aspect) but also to notice the reasons for one or another interpretation (historical aspect). In P. Tychyna's works H. Skovoroda is inscribed in the character's historical time (Koliivshchyna) in the same way as the author of the poem is inscribed in his historical reality (Sovietism), while in V. Stus’s poems both the character and the author are outside their time (Koliivshchyna and Sovietism respectively). For both poets — H. Skovoroda and V. Stus — the external appeared as transient, and ‘the inner man’ had the status of eternal one. Tychyna and V. Stus use the image of Н. Skovoroda as their alter-ego. The former author describes Н. Skovoroda as a revolutionary who stands on the principles of class ideology. Tychyna had been writing his poem-symphony “Skovoroda” in the period from the formation of Soviet power to the time of Stalinism as its most brutal version. This poem-symphony is a tribute to the time, which helped him phisically survive. In V. Stus’s version, Н. Skovoroda is thinking about moral self-improvement. He is a philosopher who cares for the fate and future of the Ukrainian people. V. Stus, living under the Soviet system, did not accept it and put up a strong resistance to it as a representative of the sixtiers. Stus’s poetry considered in this article may be regarded as a polemic with the poem-symphony “Skovoroda” by P. Tychyna. Moreover, the poem “Introduction to the poem “Skovoroda” by V. Stus shows that this polemic was planned in the format of the same genre — the poem, although it never unfolded, remaining only in fragments. Tychyna’s work also has a fragmentary nature due to both the long time of writing and the two-layered image of H. Skovoroda. The poet tried to show Skovoroda as a philosopher and a revolutionary (with the dominance of the latter).
BETWEEN FEELING AND INTELLECT: THE PHILOSOPHY OF LOVE IN THE NOVEL “THE DISEASE” BY YEVHEN PLUZHNYK
Authors: Hirniak Mariana
Published: October 2022

The primary aim of the paper is to clarify the main approaches to the philosophy of love, represented in the intellectual novel “The Desease” by Yevhen Pluzhnyk, to outline the sociocultural footing of the issues, raised in the work, as well as to bring to light the relationship of reflections on multidimensionality of love and the characters’ attempts to comprehend the peculiarities of human existence in the world. The methodological premises and theoretical frameworks for the research were provided by the studies on psychoanalysis, hermeneutics, philosophical and literary anthropology. While trying to understand the essence of love, the characters of Pluzhnyk’s novel, like the philosophers from different epochs, distinguish among love-passion, love-friendship, family love, which is developed in the matrimony, and ‘true love’ that is close to the divine one. The ‘true love’ is a willingness to sacrifice as well as realizing the uniqueness of other person; it motivates to feel responsibility for Other and to see him/her not from a selfish but from a values-based perspective.

However, the relationships between the characters along with their reflections on love in the novel by Pluzhnyk are not an ordinary illustration of the different philosophical concepts. The writer also actualizes the ideological context of the 1920s and encourages his characters to think whether love between the representatives of the hostile social ‘classes’ is possible and whether the ‘new’ human has the right to love at all. Comprehension of the phenomenon of love in the novel “The Desease” is intertwined with the reflections on the identity of the person, on his/her internal crisis, provoked by the rationalistic approach to life, as well as on the peculiarities of the dialogue with the Other. The characters of the novel also seek to understand ‘the science of life’, to solve the problem of separating private and public spaces of existence, to grasp the contradistinction of the value positions ‘to take’, aimed at the self, and ‘to give’, which is laid in the basis of love and appears to be an important feature of the human entity.
THE AMBIGUITY OF INTERTEXT: SOURCES AND FUNCTIONS OF QUOTATIONS IN PAVLO ZAHREBELNYI’S NOVEL “I, BOHDAN (CONFESSION IN GLORY)”. PART ONE
Authors: Nazarenko Mykhailo
Published: October 2022

The paper is the first part of a study on the poetics of intertext in Pavlo Zahrebelnyi’s novel “I, Bohdan”. The work by Zahrebelnyi vividly illustrates the difference between the intention of the author and the intention of the text. The writer’s self-commentaries were inevitably ideologically engaged, while the intention of the text, that is, the textual strategy of the novel, can be reconstructed. Special attention should be paid to the textual points where the senses are generated and tensions or contradictions between different levels of the text emerge — especially those between direct utterance and intertextual subtext. Thus, the definition of the intention of the text is at the same time its deconstruction, in the Derridian sense of the word. The unambiguity of the ideological content of the novel is greatly complicated by the introduction of the direct and hidden quotations and allusions to the writers who lived and worked long after Khmelnytskyi’s time. These authors may be Ukrainian (Skovoroda, Shevchenko, Franko, Kotsiubynskyi, Tychyna, Sosiura), Russian (Pushkin, Akhmatova, Pasternak, Bakhtin), European and American (Mickiewicz, Faulkner, Churchill). The narrator of the novel is Bohdan Khmelnytskyi, a monument in the Kyiv square and at the same time a hetman who’s dying in 1657. The hero exists beyond time and at every point in time. Anachronistic quotations contribute to the creation of the image of the hetman as the embodiment of all the Ukrainian history and culture in the world context. The narrator sometimes enters into a dialogue with the authors of the original texts and may argue with them. Numerous (or even all) literary versions of Khmelnytskyi’s image, in the Polish and Ukrainian paradigms, the late populist and the socialist realist ones, are presented as dubious or simply false. The main objects of controversy are Sienkiewicz (as the author of the novel most hostile to the hetman) and Shevchenko (as the author most critical towards Khmelnytskyi in the Ukrainian tradition). Bohdan as the founder of the new Ukrainian nation is equal to Shevchenko as a historical figure and prophet; the narrator of the novel, although he disagrees with Shevchenko’s opinion, still cites it. The reader, in the end, must decide for himself whom he trusts more and for what reason. Since Shevchenko’s ruthless words are quoted in the first chapter of the novel, the rest should be read in this — extremely ambiguous — ideological perspective.
Effectiveness of using google form in evaluation of students' learning outcomes of UMNU Kebumen during the covid-19 pandemic
Authors: Wahyuningsih Endang , Ferita Rolina Amriyanti
Published: October 2022

The purpose of this study is to determine  the effectiveness of using Google Forms in evaluating learning outcomes for discrete mathematics courses of UMNU Kebumen students during the Covid-19 pandemic. Evaluation of learning outcomes is needed to find out the results of the student learning process. During the Covid-19 pandemic, with a government circular, learning and evaluation are carried out by online. The increasing of online learning give a challenge for educators to choose the right method to facilitate students in online learning, especially in terms of assessment. One of the applications that can be used as an online assessment is Google Forms. This study uses a quantitative-descriptive approach. There were thirty-seven students who became respondents in this study. The use of the Google Forms  application in evaluating student learning outcomes turned out to be "effective" with the percentage of student completeness of 78.38%, namely in the "good enough" category. This result prove that the use of Google Forms as a medium to evaluate student learning outcomes is effective during the Covid-19 pandemic.
Kamusal Alanların İdeolojik Kurgusu: Bir Eleştirel Toponimi Denemesi
Authors: BOZDOĞAN Selim , BENEK Sedat
Published: October 2022

Yer adlarıyla ilgili Türkçe literatürdeki çalışmaların büyük çoğunluğunun, olguyu nesnelleştirerek mevcut verilerin betimlenmesi, sınıflandırılması ve sayısallaştırılması şeklinde incelediği saptanmıştır. Olguya sağlanan bu pozitivist ayrıcalığın, adlandırmanın doğasında yatan iktidar ilişkilerinin göz ardı edilmesine neden olduğu belirlenmiştir. Bu çalışmanın amacı, adlandırma pratiklerinin iktidar ve ideoloji ile olan ilişkisini, teorik bir çerçevede tartışmaktır. Bu tartışma, “iktidar mutlak mekân perspektifi ile adlandırır” varsayımından hareket etmektedir. Çalışmanın teorik ve kavramsal (gösterge, ideoloji) bağlamı, mutlak mekân eleştirisine dayanmaktadır. Bu eleştiri; iktidar, adlandırma, ideoloji ve gösterge kavramlarından hareketle teorik bir okuma biçimine yoğunlaşmaktadır.
Studi Komparatif Prestasi Belajar Praktikum Ilmu Dasar Keperawatan bagi Mahasiswa yang Daring dan Mahasiswa yang Hybrid di Era New Normal
Authors: Muthmainnah Muthmainnah , Muthia Rahmi , Susmiati Susmiati , Nelwati Nelwati
Published: October 2022

WHO mencatat hingga awal November 2021 terdapat 248 juta orang menderita Covid-19 di 223 negara. Sebanyak 5,01 juta masyarakat yang terkena Covid-19 meninggal dunia. Kasus terkonfirmasi COVID-19 Provinsi Sumatera Barat sampai tanggal 2 November 2021 sebanyak 89 ribu orang. Menuju era new normal, perlu adanya akselerasi menormalkan kehidupan kampus dengan mengkombinasikan pembelajaran daring dan luring (hybrid learning) termasuk mahasiswa keperawatan UNAND. Tujuan penelitian yaitu mengetahui perbandingan prestasi belajar mahasiswa setelah praktikum daring dan hybrid mata kuliah Ilmu Dasar Keperawatan. Metode yang digunakan kuantitatif non eksperimen dengan analisis komparasional. Sampel berjumlah 122 responden menggunakan teknik simple random sampling. Teknik analisis data menggunakan uji mann whitney. Hasil tes menunjukkan bahwa mahasiswa yang praktikum Ilmu Dasar Keperawatan daring memiliki nilai median 69,8, sedangkan mahasiswa yang praktikum Ilmu Dasar Keperawatan hybrid memiliki nilai median 74,6. Hasil analisis data dengan uji mann whitney menunjukkan bahwa tidak terdapat perbedaan prestasi belajar mahasiswa yang praktikum Ilmu Dasar Keperawatan daring dengan mahasiswa yang praktikum Ilmu Dasar Keperawatan hybrid. Hal ini menunjukkan bahwa metode praktikum tidak mempunyai pengaruh yang signifikan terhadap prestasi belajar Ilmu Dasar Keperawatan.
EDUKASI KELOMPOK REMAJA DALAM PENGELOLAAN INFORMASI PARIWISATA BERBASIS MEDIA SOSIAL DI WILAYAH PESISIR
Authors: Tarifu La , Jopang Jopang , Sarmadan Sarmadan , Sudirman Faturachman Alputra , Sarpin Sarpin , Rajab Muhammad , Tawulo Megawati Asrul , Yusuf Bakri , Kasim Syaifudin Suhri
Published: October 2022

The development of tourism in the coastal area of Soropia District, Konawe Regency has not shown maximum results so that it does not have an impact on increasing people's income in the region. The purpose of this community service is to provide an understanding to the community about the tourism potential that exists in the coastal area of Soropia village and provide understanding to groups of teenagers in coastal areas on the importance of managing tourism information. The method used in educating youth groups in managing social media-based tourism information in coastal areas uses the lecture method by describing various information on the potential of local tourism products in Soropia Village. The results of community service show that the management of tourism information in the coastal area of Soropia District, Konawe Regency has not fully involved the local community, including youth groups. Through this activity, Soropia village youth have understood the importance of their role in disseminating information related to tourism potential in the coastal area of Soropia village, one of which is through digital posters that can be disseminated through social media. Dissemination of the digital poster through social media to promote tourism and attract the wider community to travel in Soropia village. This activity has formed an understanding of youth groups in the coastal area of Soropia District, Konawe Regency regarding the management of tourism information.
Edirneli Nazmî Dîvânı’nı Tezkireler Işığında Okumak: Bir Sanatçının Üslup Değerlendirmelerinden Sahile Vuran İnciler
Authors: EKİCİ Ayşegül
Published: October 2022

Şairler ilâhî bir kudretle şiir söyleme yetisine sahip olup günlük konuşma dilinin söz dağarcığı onlar için kifayetsiz kalmaktadır. Böyle bir durumda sanatçı, duygu dünyasını karşılayacak yeni kelimeler türetemeyeceği için var olan kelimelere yeni anlamlar yükleme yoluna gider. Geniş hayalleri ve derin duyguları onu bu yola sevk eder. İşte bu serüvendeki farkındalık noktasında her sanatçı kendi üslubunu oluşturur. Terry Eagleton’un ifadesiyle bir yazı parçasının yüzeyi gizli derinliklerinin itaatkȃr yansımasından başka bir şey değildir. Modern dünyada üslup değerlendirmeleriyle alakalı dil bilimsel metodlar denenmekle beraber gelenekten de istifade edilmesi gerekmektedir. Tezkireler, çok sayıda Osmanlı Dönemi şairlerinin biyografisini sunarken sanatçının dili nasıl kullanması gerektiği konusunda ipuçları sunar. Üslupla ilgili bu değerlendirmelerde ise ortak bir terminolojinin kullanıldığı dikkat çekicidir. Tezkirelerdeki bu terminoloji ışığında bir sanat eserine nasıl bakılması gerektiği ve eserin nasıl yazılması gerektiği konusundaki düşüncelere sahip olmak mümkündür. Edirneli Nazmî Dîvân’ı hem birçok türü barındırması hem de şiir sayısı bakımından oldukça dikkat çekici bir eserdir. Çalışmamızın amacı XVI. yüzyıl şairlerinden Edirneli Nazmî Dîvân’ını tezkireler ışığında okuyarak geleneksel terimlerle üslup bilgisinin çalışılabileceğini göstermektir. Üç bölümden oluşan çalışmamızın ilk bölümünde; tezkirelerdeki poetik terimlerden yola çıkarak Edirneli Nazmî’nin üslup değerlendirmeleri tespit edilmiştir. Bu bölümde Dȋvȃn içinde yer alan Arz-ı Hâl-i Be-Pȃdişȃh isimli mesnevȋ sebeb-i te’lîf bölümünden dolayı konu dahilinde ayrıca incelenmiştir. İkinci bölümde, ilk bölümden hareketle şairin poetikası ortaya konmuştur. Son bölümde ise şairin poetikasıyla eserinin ne kadar örtüşüp örtüşmediği konusunda karşılaştırma metoduna gidilerek çıkarımlarda bulunulmuştur.
Software Systems Implementation and Domain-Specific Architectures towards Graph Analytics
Authors: Jin Hai , Qi Hao , Zhao Jin , Jiang Xinyu , Huang Yu , Gui Chuangyi , Wang Qinggang , Shen Xinyang , Zhang Yi , Hu Ao , Chen Dan , Liu Chaoqiang , Liu Haifeng , He Haiheng , Ye Xiangyu , Wang Runze , Yuan Jingrui , Yao Pengcheng , Zhang Yu , Zheng Long , Liao Xiaofei
Published: October 2022

Graph analytics, which mainly includes graph processing, graph mining, and graph learning, has become increasingly important in several domains, including social network analysis, bioinformatics, and machine learning. However, graph analytics applications suffer from poor locality, limited bandwidth, and low parallelism owing to the irregular sparse structure, explosive growth, and dependencies of graph data. To address those challenges, several programming models, execution modes, and messaging strategies are proposed to improve the utilization of traditional hardware and performance. In recent years, novel computing and memory devices have emerged, e.g., HMCs, HBM, and ReRAM, providing massive bandwidth and parallelism resources, making it possible to address bottlenecks in graph applications. To facilitate understanding of the graph analytics domain, our study summarizes and categorizes current software systems implementation and domain-specific architectures. Finally, we discuss the future challenges of graph analytics.
Interaksi Sosial Antara Mahasiswa Muslim Dengan Mahasiswa Non Muslim di Lingkungan Universitas Syiah Kuala
Authors: Sanusi Sanusi , Maimun Maimun , Sirait Gabriella Martina
Published: October 2022

Tujuan penelitian ini untuk menjawab permasalahan yaitu (1) bagaimana interaksi sosial yang terjadi antara mahsiswa muslim dengan mahasiswa non-muslim dalam lingkungan kampus Universitas Syiah Kuala, (2) apa saja faktor penghambat interaksi sosial antara mahasiswa muslim dengan mahasiswa non-muslim dalam lingkungan kampus Universitas Syiah Kuala. Penelitian ini menggunakan metode kualitatif dan jenis penelitian deskriptif. Subjek penelitian yaitu mahasiswa muslim dan mahasiswa non-muslim yang berjumlah 10 (sepuluh) orang, dengan teknik pengumpulan data wawancara mendalam. Hasil penelitian menunjukkan bahwa (1) interaksi sosial yang terjalin antara mahasiswa muslim dengan non-muslim yaitu kerjasama dalam mengerjakan proyek kelas atau penyelesaian sebuah acara baik didalam kelas maupun didalam organisasi kemahasiswaan, persaingan dalam hal akademik, konflik mengenai agama tidak pernah terjadi dan akomodasi, kesadaran akan kedewasaan sesama mahasiswa dalam penyelesaian suatu masalah, (2) faktor penghambat interaksi sosial antara mahasiswa muslim dengan mahsiswa non-muslim yaitu simpati untuk memulai interaksi sosial diawal sangat canggung, berlebihan dalam memberikan kritik terhadap karya atau tugas sesama mahasiswa, hambatan dalam interaksi antara mahasiswa muslim dengan mahasiswa non-muslim yaitu adanya perbedaan sikap mahasiswa dalam menanggapi dan mengerjakan sebuah proyek kelas yang ditugaskan oleh dosen. Upaya untuk mengatasi hambatan-hambatan tersebut yaitu dengan memberikan teguran terhadap mahasiswa yang melakukan kritikan secara berlebihan tersebut, mengajak mahasiswa yang sulit bergaul untuk melakukan kegiatan bersama. Hasil temuan di lapangan yang telah dipaparkan menunjukkan kesesuaian dengan asumsi teori aksi dari Talcott Parsons yang menjelaskan bahwa salam bertindak, manusia juga menggunakan  cara, teknik, prosedur, metode serta perangkat yang diperkirakan cocok untuk mencapai tujuan tertentu.