bluuebunny/crossref_metadata_2025 huggingface dataset:
Sítio histórico da Prainha de Vila Velha/ES
Authors: Oliveira Melissa Ramos da Silva , Pinheiro Victória Christina Simões
Published: December 2021

A memória contribui para manter o patrimônio cultural presente na história de um povo, porém como se dá essa relação afetiva entre usuário e espaço? O objetivo deste trabalho é investigar, com aplicação de questionários online sobre a Prainha para um público geral e específico, como os mecanismos cerebrais – memória, atenção e sentimentos – são acionados no processo de reconhecimento dos bens culturais do sítio histórico da Prainha. A partir de questionários procurou-se investigar as memórias da população e como elas podem impactar na preservação do sítio histórico. Os resultados evidenciaram que as memórias são fonte vida para a própria história.
Toxicity of entomopathogenic fungi against Spodoptera frugiperda larvae under laboratory conditions
Authors: Muhammad Ayaz Shahzad , Muhammad Irfan , Ahmad Abdul Wahab , Farhan Zafar , Abdulrehman Abdulrehman , Muhammad Shuban , Muhammad Raheel Saleem
Published: December 2021

Maize Fall Armyworm (FAW), Spodoptera frugiperda (Lepidoptera: Noctuidae) is considered an economically important pest and becoming the main threat to food security. This polyphagous pest is widely distributed in various countries of the world especially tropical and subtropical regions. The toxicity of two entomopathogenic fungi such as Metarhizium anisopliae and Beauveria bassiana were evaluated against 2nd instar larvae of FAW under controlled conditions. The results showed that among tested entomopathogenic fungi, B. bassiana was found more toxic than M. anisopliae. B. bassiana caused 79% larval mortality while M. anisopliae 59%. M. anisopliae and B. bassiana were showed LT50 of 84.01 h and 80.99 h, respectively. M. anisopliae and B. bassiana were showed LC50 of 1.3×107 and 1.8×107 spores ml−1, respectively. The current study concluded that Entomopathogenic fungi can give effective control against early instar and further studies are needed to check the efficacy against older instars under field and laboratory conditions.
[RETRACTED] Green Fast Keto: Weight Loss Diet Pills Health Risks and Shocking Results? v1
Authors: Fast Keto Green
Published: December 2021

[RETRACTED]

This bodyweight decline supplement will assist your power with welling
Performance enhancement in athletes: a survey to investigate the current clinical practice of Italian sport physiotherapists v1
Authors: Alessio Sauchelli Pasquale
Published: December 2021

Background and rationale Professional sport physiotherapist profile is characterised by eleven specific competences, defined by standards which are described by the Sports Physiotherapy for All (SPA) project [1]. Among these, performance evaluation and enhancement are fundamental in order to let athletes achieve their specific sport gestures best execution with a relevant impact on functional outcome. They alsoinfluencepositively on the decrease of injury risk [2-4]. Based on this cultural background, it is necessary that professionals evaluate their own clinicalpractice in order to match international standards, increase their work quality satisfying the functional requests of the sport environment, matching the perspective changes driven by the scientific community [2]. Study aim This survey aims to: •assess how Italian sport physiotherapists perform education and enhancement of the athlete performance in their clinical practice. •evaluate confidence of Italian professionals in performing such competence while managing the athlete performance. The average competencies of the analysed sample will be quantified and compared with what is set by the current scientific evidences regarding performance enhancement in athletes. Study design This observational cross-sectional study will be conducted in Italy through a digital questionnaire administration to a sample of 1093 sport physiotherapists [5]. Considering around 65000 Italian physiotherapists as a reference population, a confidence interval of 95% and a relative standard error of 3%, the necessary sample in order to have relevant results for the whole selected population is 1093 professionals [6-7]. This sample composed of Italian professionals will be recruited through social channels and/or newsletters sent by e-mail. The questionnaire will be filled in only after privacy law requirements acceptance and meeting inclusion criteria by the recruited sample. Results from this survey will be reported according to criteria set by STROBE guidelines and will be quantified and interpreted following the above-mentioned study aim. This study will be performed in accordance with the Checklist for Reporting Results of Internet E-survey criteria (CHERRIES) and with ethical principles contained in the Helsinki Declaration [8-10]. Committee on Bioethics of University of Pisa approved the present study.
High Throughput SARS-COV-2, PMMOV, and BCoV quantification in settled solids using digital RT-PCR v2
Authors: Topol (Verily Life Sciences) Aaron , not provided marlene.wolfe , White (Verily Life Sciences) Brad , Wigginton Krista , B B Boehm Alexandria
Published: December 2021

This process instruction describes the steps for quantitative analysis of nucleic acid from SARS-CoV-2 with a triplex Reverse Transcriptase droplet digital Polymerase Chain Reaction (RT-ddPCR) assay targeting the N Gene, S Gene and ORF1a and a duplex assay targeting Bovine Coronavirus Vaccine (BCoV) and Pepper Mild mottle virus (PMMoV) in extracted and purified RNA samples from solid wastewater samples for population level SARS-CoV-2 community surveillance. RT-ddPCR is a modified version of conventional RT-PCR workflows which involves separating the reaction mixture into many partitions (~20,000) before thermal cycling which allows for direct absolute quantification of the target RNA molecules. This protocol uses RNA extracted using this protocol: High Throughput RNA Extraction and PCR Inhibitor Removal of Settled Solids for Wastewater Surveillance of SARS-CoV-2 RNA. That RNA is generated from samples subjected to pre-analytical steps outlined in: High Throughput pre-analytical processing of wastewater settled solids for SARS-CoV-2 RNA analyses. This protocol describes 2 separate PCR reactions, one containing primer/probe mixtures targeting the three SARS-CoV-2 targets and one containing primer/probe mixtures targeting BCoV and PMMoV. BCoV is spiked into samples before nucleic acid extraction and serves as a process control as well as an indicator of PCR inhibition. PMMoV is an enveloped virus which is abundant in human fecal waste and serves as an endogenous control for data normalization. PMMoV RNA is abundant at such high levels in wastewater samples that the samples must be diluted by a factor of 100 before quantification. The readout of this assay is a concentration of each target in the extracted RNA samples (copies/uL). Scope This process instruction applies to quantitative analysis of nucleic acid from SARS-CoV-2 RNA from solid wastewater samples with ddPCR using a Bio-Rad AutoDG Droplet Digital PCR system consisting of the AutoDG Automated Droplet Generator and the QX200 droplet reader.
FPCount protocol - Full protocol v1
Authors: Csibra Eszter
Published: December 2021

FPCount is a complete protocol for fluorescent protein calibration, consisting of: 1. FP expression/purification using Thermo's HisPur Cobalt Resin. 2. FP concentration determination in a microplate reader. 3. FP fluorescence quantification in a microplate reader. Results can be analysed with the corresponding R package, FPCountR. --- Summary 1. Expression 2. Harvesting/Washing 3. Lysis 4. Fractionation 5. Gel1: Verification of Expression/Fractions 6. Purification 7. Gel2: Verification of Purification 8. Protein concentration and buffer exchange 9. Quantification of FP concentration (part1) 10. Quantification of FP fluorescence 11. Quantification of FP concentration (part2) 12. Protein Storage 13. Calibration of Plate Reader
FPCount protocol - in-lysate (purification free) protocol v1
Authors: Csibra Eszter
Published: December 2021

FPCount is a complete protocol for fluorescent protein calibration, consisting of: 1. FP expression and production of cell lysates. 2. FP concentration determination in a microplate reader. 3. FP fluorescence quantification in a microplate reader. Results can be analysed with the corresponding R package, FPCountR. This in-lysate version of the protocol uses the ECmax protein quantification protocol of FPs in lysates and does not require His-tag purification of the FPs. Note that it is only suitable for FPs with entries in FPbase. If you want to verify or validate results, it's recommended you follow the 'short' protocol, which requires FP purification, or the 'complete' protocol, which requires FP purification and compares three protein quantification methods. --- Summary 1. Expression 2. Harvesting/Washing 3. Lysis 4. Fractionation 8. Protein concentration and buffer exchange 9. Quantification of FP concentration (part1) 10. Quantification of FP fluorescence 12. Protein storage 13. Calibration of Plate Reader
PENDIDIKAN KARAKTER PEDULI LINGKUNGAN MELALUI PROGRAM ADIWIYATA BERBASIS EKOPEDAGOGIK
Authors: Handayani Trisni , MS Zulela , Yudha Chrisnaji Banindra
Published: December 2021

The moral degradation and character of the nation's children is increasingly worrying. This phenomenon can damage the realization of the superior generation of the nation's generation. So it takes a touch in basic education that can provide reinforcement and the formation of student character in loving the environment in a sustainable manner. This study aims to determine the effect of the Adiwiyata program on environmental education based on ecopedagogic-based care for high-class students at Cijantung 03 Jakarta Primary School The research method used is a descriptive associative quantitative approach, a simple paradigm research design. The sample used was stratified random sampling with validity testing using Pearson product-moment correlation. While the reliability test uses Alfa Cronbach. Based on the analysis of the data it can be concluded that the results of this study indicate that there is a significant influence in fostering environmental care character for schools that receive the Adiwiyata-based Ecopedagogic program including habits in maintaining the cleanliness and beauty of the school environment that has an impact on students' habits of maintaining, preserving, and discarding orderliness. rubbish and recycle the garbage in the environment
PENGARUH KEMAMPUAN LITERASI MEMBACA TERHADAP PRESTASI BELAJAR SISWA SEKOLAH DASAR
Authors: Amri Saeful , Rochmah Eliya
Published: December 2021

The background of this research is the low of reading literacy skills in SDN Pegagan. The low of reading skills is thought to have an effect on student achievement as well. This is indicated by the results of student achievement that are still low. The purposes of this research are to (1) Know the reading literacy skills of student (2) Know the level of student achievement, and (3) Know the influence of reading literacy skills on student achievement in SDN Pegagan. The study design used quantitative survey research with a sample of 88 students in SDN 1, 2, and 3 Pegagan. Data analysis used simple linear regression test. The results showed that (1) the reading literacy skills of students was quite sufficient at 67.53%, (2) The students' learning achievement was classified as very good at 81%, and (3) There was a significant influence of 5.4% between reading literacy skills and student achievement learning.
SHADOW TEACHER FOR SPECIAL NEEDS STUDENTS: CASE STUDY CLASS VI TAMAN MUDA IBU PAWIYATAN YOGYAKARTA
Authors: Qiftiyah Maratul , Calista Wina
Published: December 2021

This research is to describe the shadow teacher for students with special needs at Taman Muda Ibu Pawiyatan Yogyakarta Elementary School. This type of research is qualitative research. This is a qualitative descriptive study which produces descriptive data in the form of words based on detailed and in-depth field research. The subject of this study was the shadow teacher in class VI. Data collection techniques using observation and interviews. As for the data analysis which is done which includes: data reduction, data presentation, and concluding. Based on the results of the study it can be concluded that the shadow teacher who accompanies students with special needs (mild intellectual impairment) in class VI is doing an authoritarian accompaniment. The mentoring makes students experience pressure when learning, it is not uncommon for students to cry, and leave the classroom when learning. Also, the shadow teacher's actions disturb other students. That is what some parents in class IV agreed not to involve shadow teachers in the learning process in class.
PEMBELAJARAN PERSEN DENGAN MENGGUNAKAN MEDIA DOWNLOAD BAR PADA SISWA KELAS 5 SEKOLAH DASAR
Authors: Oktiningrum Wuli
Published: December 2021

Abstract:. This research was conducted on class V students of SD Negeri 179 Palembang, with the aim of knowing students' understanding of the percent material by using media download bars. The subjects in this study were 28 students with heterogeneous abilities. The research methodology used in this study is Design Research with a Realistic Mathematics Education (RME) approach. This study fulfilled five characteristics of RME, namely the use of laptops, computers and downloads of the internet (using of context), pictures of download bars (use of models), activities in LKK (pupil own creations and contributions), presentation and group discussion (interactivity) and problems change fractions into percent (intertwining). The results of this study indicate that students have been able to solve the percent problem by using media download bars.Keyword: Download Bar, Percent, RME, Design Research Abstrak: Penelitian ini dilakukan pada siswa kelas V SD Negeri 179 Palembang, dengan tujuan  mengetahui pemahaman siswa pada materi persen dengan menggunakan media download bar. Subjek pada penelitian ini sebanyak 28 siswa dengan kemampuan yang heterogen. Metodologi penelitian yang digunakan pada penelitian ini adalah  Design Research dengan pendekatan Realistic Mathematics Education (RME). Penelitian ini telah memenuhi lima karakteristik RME yaitu penggunaan laptop, computer dan download di internet (using of context), gambar bar download (penggunaan model), kegiatan pada LKK (pupil’s own creations and contributions), presentasi dan diskusi kelompok (interactivity) dan masalah merubah pecahan kedalam bentuk persen (intertwining). Hasil penelitian ini menunjukkan bahwa siswa telah mampu menyelesaikan soal persen dengan menggunakan media download bar.Kata Kunci: Download Bar, Persen, RME, Design Research
THE STATE OF BASIC EDUCATION IN NIGERIA BORDER COMMUNITIES
Authors: Muhinat BELLO Bolanle
Published: December 2021

The study investigated the state of basic education in the Nigerian international border communities of Sokoto State. A descriptive survey research design was adopted for the study. A multistage sampling technique was adopted for the selection of  597 out of 3,876 respondents. A 29 items four-point-Likert scale Researcher’s designed questionnaire that was translated into Arabic and Hausa languages with psychometric properties of content validity 0.80, 0.75, and 0.87and a reliability coefficient of 0.76, 0.82, and 0.71 while the interview items have a content validity of 0.77 and a reliability coefficient  0.78 was used to elicit the needed data. descriptive and Inferential statistic was used to analyze the data. Findings revealed that parental, teachers, governmental, and facilities factors pose challenges to basic education in the border areas, among others. Educational policymakers are recommended to take necessary measures to decentralized the curriculum of the education system in Nigeria to takes care of the educational needs of a different society.
PERANAN TECHNOLOGICAL PEDADOGICAL CONTENTS KNOWLEDGE (TPACK) DALAM KREATIVITAS MENYUSUN PERANGKAT PEMBELAJARAN
Authors: Jannah Widia Nur , Rahman Rahman
Published: December 2021

Tujuan dari penelitian ini adalah untuk melihat peranan Technological Pedadogical Contents Knowledge (TPACK) dalam kreativitas mahasiswa PGSD merancang perangkat pembelajaran Bahasa Indonesia SD. TPACK adalah pengetahuan tentang pembelajaran yang terintegrasi teknologi yang didasari pada analisis karakter materi dan aspek pedagogik. Metode penelitian menggunakan eksperimen (Single-One Group Pretest-Posttest Design). Intrumen penelitian yang digunakan adalah penilaian portofolio. Efektifitas dianalisis dengan menggunakan n-gain. Subjek penelitian adalah mahasiswa PGSD semester empat Universitas Muhammadiyah Cirebon tahun akademik 2019/2020. Kesimpulan penelitian ini terlihat adanya peningkatan yang signifikan pada kemampuan TPACK dalam kreativitas mahasiswa PGSD menyusun perangkat pembelajaran. Peningkatan dapat dilihat dari setiap indikatornya, yaitu pada keluwesan dalam konten 0,89, kebaruan  pedagogik dalam teknologi 1,31, serta elaborasi konten dan teknologi 1,00. Selain itu, berdasarkan uji t diketahui bahwa t hitung sebesar -28,75 dan taraf signifikansi yaitu 0,000 sehingga dapat disimpulkan bahwa  di tolak dan  diterima, dengan kata lain model blended learning berbasis project dapat meningkatkan kemampuan TPACK dalam kreativitas menyusun perangkat pembelajaran Bahasa Indonesia mahasiswa calon guru SD. Luaran dari penelitian ini menghasilkan perangkat pembelajaran seperti Rencana Pelaksanaan Pembelajaran (RPP) kurikulum 2013 dan media pembelajaran berbasis IT.
Information about the XII International Conference of the Russian Association for Human Reproduction "Reproductive Technologies Today and Tomorrow"
Authors: Korsak V. S.
Published: December 2021

From 3 to 5 September 2003, the XII International Conference of the Russian Association for Human Reproduction Reproductive technologies today and tomorrow took place in St. Petersburg. It was attended by about 400 doctors from all over Russia, from Ukraine, Belarus, Kazakhstan, Georgia, Uzbekistan, Latvia, Sweden, Slovenia, Austria and Scotland.
Influence of surgical intervention on life quality of gynecological patients
Authors: Ailamazyan Eduard K. , Vasilieva I. Y.
Published: December 2021

For investigation of the influence of surgical intervention on life quality of gynecological patients 72 women were inspected, whose clinical picture had as a leading syndrome the chronic pelvis pain (CPP), and 32 women with womb myoma, who did not complain against a pain in the pelvis. Life quality was evaluated before surgical intervention and in 10-12 months after it.

It was detected that due to the big expression of psyching disorders of neurotic level in women with CPPtheir starting level of quality life was considerably lower than in patients with womb myoma.

Inspection results manifested that operative treatment led tc improving life quality evaluating in 10-12 months after surgical intervention in women with womb myoma, but did not lead tc changes in majority of patients with CPP.
Eco in infertility. Inspection of pregnancy and delivery
Authors: Savelieva G. M. , Kurtser М. A. , Krasnopolskaya K. V. , Eroyan L. K.
Published: December 2021

During the period from 1996 to 2002, the IVF department of the Family Planning and Reproduction Center carried out IVF treatment in 2218 infertile patients. Based on many years of experience, the results of using this method are summarized, taking into account the modifications made to it, developed by the staff of the Center. Specific recommendations for the use of endosurgical methods for restoring natural fertility and IVF in cases of female infertility associated with tuboperitoneal factors and myoma are presented. The course of pregnancy and childbirth in patients with IVF programs has been analyzed and approaches have been outlined to reduce their reproductive losses.
The application of simultaneous treatment combined with endovideosurgery in case of gynecological disorders
Authors: Singaevsky S. B. , Yaroslavsky V. K. , Borisov А. V. , Atlasov V. O. , Revina O. G.
Published: December 2021

In this article we present considerable date about simultaneous operations in case of combination both surgical and gynecological pathology. The character of operative interactions is also discussed. There we show the results that characterize the application of laparoscopy and hysteroresectoscopy in case of treatment of differently located uterus myoma.
Ectopic pregnancy - modern aspects of diagnosis and treatment. Clinical and economic effect of the use of modern medical technologies in the treatment of tubal pregnancy
Authors: Komlichenko Е. V. , Tsivyan B. L. , Urakova R. V.
Published: December 2021

The authors present analysis of outcomes 768 operations for ectopic pregnancy by laparoscopy. They are offered the new method blood reinfusion during laparoscopy and the original algorithm of diagnosis an ectopic pregnancy. Laparoscopy is the main method of treatment for ectopic pregnancy.
Experience of surgical treatment of manifesting forms of adenomyosis
Authors: Rukhliada N. N. , Tsveliov Y. V.
Published: December 2021

One describes in this article the technique of performing surgeries with saved organs at manifested adenomyosis, one presents the treatment results of women with various clinico-morphological disease forms by means of different surgical methods.
Laparoscopy in differential diagnostics of gynecolodical pelvioperitonitis and acute appendicitis
Authors: Kalchenko O. V. , Vasilenko L. N. , Sabitov S. S. , Karatiuk T. I. , Kiseliov L. E. , Livshits M. Y. , Tastemirov B. A. , Mert N. E.
Published: December 2021

Diagnostic laparoscopy solves all the problems arising from the doubts in diagnosing acute appendicitis and pelvioperitonitis of gynecological genesis. It must be widely used in the cases where clinical and laboratory data do not allow to reliably diagnose acute appendicitis or its absence, this method also allow to specify the nature of the patient's disease.
Asessment of laparoscopy role for complex diagnostics and treatment of spreaded forms of purative-inflam- matory diseases of womb appendices
Authors: Abashin V. G. , Novicov E. I. , Iliin А. B. , Arakelian B. V. , Melnikov А. S.
Published: December 2021

Here, data are presented about 150 laparoscopic surgical operations in women with spreaded forms of purativeinflammatory diseases of womb appendices. Laparoscopy is optimal diagnostic and medical intervention in case of gynecological pelvioperitonites. Patients with purative-inflammatory diseases of womb appendixes, inclusions of close organs and wide peritonitis need in the surgical aid trough laparotomic access.
Menopausal metabolic syndrome and obesity
Authors: Repina М. A.
Published: December 2021

In this review, it is presented the importance for metabolic processes of decreasing estradiol concentration in connection with prolapsus of ovary function in women. Here, influence of different modes of substitute hormonal therapy, of different progestagenic components included in preparations is discussed.
Contribution of K.P. Ulezko-Stroganova то the investigation of the problem of female genitalia morphology
Authors: Tsvelev U. V.
Published: December 2021

The article is devoted to the biographical sketches of one of the most distinguished pathologists in gynecology K.P. Ulezko-Stroganova. The most contribution was done in the questions of myometrial tumours, adenomyosis and endometriosis.
Immunocompetent cells in the endometrium of patients with infertility and external genital endometriosis
Authors: Kulakov V. I. , Volkov N. I. , Bespalova J. V.
Published: December 2021

The article reports on the results of an immunohistochemical study of the endometrium of patients with infertility and external genital endometriosis. The analysis of the dynamics of the distribution of immunocompetent cells in the endometrium of patients with infertility due to external genital endometriosis in comparison with patients with infertility of tubo-peritoneal genesis was carried out.
Features of adaptation of newborns with intrauterine growth retardation
Authors: Evsyukova I. I. , Fomenko B. A. , Andreeva А. А. , Kovalchuk-Kovalevskaya O. V. , Dodkhoev D. S. , Kianksep А. N. , Tretyakova M. B. , Maslyanyuk N. A.
Published: December 2021

The morbidity, adaptation characteristics, production of melatonin and creatine kinase in newborns with intrauterine growth retardation were studied. It was found that with a symmetrical form of IUGR in newborns, there is not only a lag in growth, body weight, and the formation of postural and reflex reactions from the given gestational age, but also pronounced multiple organ failure, which significantly complicates their postnatal adaptation and, probably, determines a high frequency somatic pathology and disorders of psychomotor development in the following months of life. Children who have a lag in growth and body weight combined with a delay in the formation of postural and reflex reactions as a result of intrauterine infection and placental insufficiency of infectious genesis need therapy aimed at restoring and compensating for the impaired functions of the central nervous system and other functional systems of the body.
Activity of the brain isoenzyme creatine kinase in newborns with intrauterine growth retardation
Authors: Dodkhoev D. S. , Evsyukova I. I. , Tumasova Z. N. , Harutyunyan А. V.
Published: December 2021

The CK-BB activity in neonates with intrauterine growth retardation (IUGR) was investi-gated and the results were compared to their clinical condition in early neonatal period. The re-sults of the study have shown that the CK-BB activity was increased in neonates with symmetric IUGR and in the presence of chronic placental insufficiency of infectious genesis.
Pregnancy and delivery in patients with hepatolenticular degeneration
Authors: Vakharlovsky V. G. , Lagkueva F. K. , Kusova S. O. , Tzidaeva T. I.
Published: December 2021

Data of pregnancy course and delivery in 3 patients with hepatolenticular degeneration (GLD) a rare disease of autosomal recessive inheritance pattern are presented. In one case GLD was diagnosed prior pregnancy and treatment with cuprenil was continued during pregnancy. No progressive GLD clinical symptoms were observed. However pregnancy and delivery appeared to provoke GLD typical manifestations in other two patients. They have not got specific treatment with cuprenil during pregnancy as disease was diagnosed only after delivery.

Deliveries in patients with GLD were successful and the newborns were healthy. No evidence of cuprenil teratogenic effect on fetus was revealed in the first case. This GLD is not contraindication for successful pregnancy but it is necessary to use cuprenil for prevention of disease exacerbation.
Onco-specific sleep disorders and fatigue: tactics of psychological test and cognitive behavioral therapy
Authors: Melehin Aleksey I.
Published: December 2021

Introduction. Sleep disorders are widespread throughout the entire period of treatment of an oncological patient from the moment of diagnosis, and in many patients persist after completion of treatment. The nature of cancer and its treatment expose patients to many potential provoking and/or supportive factors that are atypical for the general population. In addition, sleep disturbance rarely manifests as a separate symptom, but more often occurs together with such symptoms as fatigue, pain, depression and/or cognitive impairment. This complicates the assessment and often requires an individual treatment plan with a team approach.
AIM. of the work is to acquaint mental health specialists, oncologists, chemotherapists with the specifics of the examination of cancer-specific insomnia and fatigue, the construction of team treatment tactics, the organization of psychotherapeutic care for cancer patients.
Results. The article describes for the first time the specifics of onco-specific insomnia and fatigue. The general predisposing and supporting factors of insomnia characteristic of cancer patients are systematized. The relationship between onco-specific fatigue and sleep disorders is shown. The role of pro-inflammatory cytokines as a common neuroendocrine-immune mechanism underlying the behavioral symptoms of sleep disorders, fatigue, depression and cognitive dysfunction in people with cancer is noted. Due to the limitations of the pharmacological approach, the purpose, forms, modes and approaches of using cognitive behavioral therapy protocols to minimize insomnia and fatigue are described. Based on the data of our foreign colleagues, we have proposed an algorithm for assessing sleep disorders in a patient with an oncological profile. The effectiveness of the standard protocol of cognitive behavioral psychotherapy of insomnia (SCBT-I) in a patient of the oncological profile Lavini Fiorentino is described in detail and shown; as well as the short protocol of CBT of cancer-specific insomnia by Eric Zo et al.; remote protocol of mindfulness enhancement therapy to minimize onco-specific fatigue Z.by Fieke et al.
Conclusions. CBT in the framework of complex treatment has a positive effect on the immune system, reducing inflammation mediated through the hypothalamic-pituitary-adrenal axis. Despite the accumulation of evidence confirming the effectiveness of this form of psychological assistance, its availability in Russia remains extremely limited and not fully appreciated.
Psychosocial, clinical, and organizational perspectives of the risks of remote work for employees` mental health
Authors: Zalmunin Konstantin  Y.
Published: December 2021

The objective of the study was to analyze the modern data on the risks of remote work influence on the employees` mental health from psychosocial, clinical, and organizational perspectives.
Methods. The analysis of literary sources, policy documents, publications in the mass media with an emphasis on the period from the beginning of the spread of the new coronavirus infection 2019-nCoV to the present.
Results. The current state of the problem of the impact of remote work on the employees` mental health in Russia and in and in other countries during the global COVID-19 pandemic is analyzed. The causal relationships of medical, social, and organizational perspectives of labor activity are considered, and strategies for prevention of negative effects are studied. The widespread using of remote work all over the world is due to the need to limit the direct interpersonal contacts of citizens to contain the spread of infection. It is established that employees of organizations that perform labor functions remotely can be recognized as a type of risk group for mental, behavioral, and addictive disorders due to medical and social perspectives. The development of self-employment and the provision of services on the principles of freelancing may contribute to reducing the number of employees covered by preventive maintenance medical examinations and complicate the early detection of mental and somatic deviations in freelance workers.
Conclusion. The result of the growing popularity of remote work is the spread of a hybrid work regime, which requires a comparative assessment of the medical and social risk factors of remote workers, amendments to several regulatory documents as well as the development of evidence based psychohygienic methodological recommendations for employers and early detection of employees with contraindications to remote work.
Comparison of the efficacy of trauma scores in predicting prognosis and hospitalization
Authors: AKÇA Hatice Şeyma , ALGIN Abdullah , ÖZDEMİR Serdar , KOÇKARA Elif , EROĞLU Serkan Emre
Published: December 2021

Purpose: The aim of this study was to compare the efficacy of ISS (injury Severity Score), RTS (Revised Trauma Score) and ViEWS (VitalPAC Early Warning Score) scoring systems in predicting prognosis and mortality.

Materials and Methods: Patients over the age of 18 who presented with multitrauma were prospectively examined between May 1, 2019 and November 1, 2019. Trauma scores, clinical outcomes within the first 24 hours, surgery requirement and 30-day mortality data were recorded.

Results: The study included 435 patients, of whom 333 (76.6%) were male. The median age was 34 (IQR: 18-90) years. It was observed that ISS, RTS and ViEWS had a significant relationship with 30-day mortality. In the ROC analysis of 30-day mortality, no statistically significant difference was observed between the ISS, RTS, and ViEWS AUC values. There was also no statistically significant difference in terms of the ISS, RTS and ViEWS according to the length of hospital stay and surgery requirement.

Conclusion: In addition to their relationship with mortality, it should be kept in mind that the investigated scoring systems may also be related to the length of hospital stay and surgery requirement.
Iterative Interference Cancellation for Multi-Carrier Modulation in MIMO-DWT Downlink Transmission
Authors: Harbi Yahya , AL-JANABI ALI , Almusa Hayder , Chafii Marwa , Burr Alister
Published: December 2021

The Multiple-Input Multiple-Output Orthogonal Frequency Division Multiplexing (MIMO-OFDM) scheme represents the dominant radio interface for broadband multicarrier communication systems. However, with insufficient Cyclic Prefixes (CP), Inter-Symbol Interference (ISI) and Inter-Carrier Interference (ICI) occur due to the time-varying multipath channel. This means that the performance of the system will be degraded. In this paper, we investigate the interference problem for a MIMO Discrete Wavelet Transform (MIMO-DWT) system under the effect of the downlink LTE channel. A Low-Density Parity-Check (LDPC) decoder is used to estimate the decoded signal. The proposed iterative algorithm uses the estimated decoded signal to compute the components required for ICI/ISI interference reduction. In this paper, Iterative Interference Cancellation (IIC) is employed to mitigate the effects of interference that contaminates the received signal due to multiple antenna transmission and a multipath channel. An equalizer with minimum mean square error is considered. We compare the performance of our proposed algorithm with the traditional MIMO-OFDM scheme in terms of bit error probability under insufficient CP. Simulation results verify that significant improvements are achieved by using IIC and MIMO-IIC for both systems.
Fuzzy solution of fully fuzzy multi-objective linear fractional programming problems
Authors: Kandasamy Ganesan , T. Loganathan
Published: December 2021

In this study, we present a novel method for solving fully fuzzy multi-objective linear fractional programming problems without transforming to equivalent crisp problems. First, we calculate the fuzzy optimal value for each fractional objective function and then we convert the fully fuzzy multi-objective linear fractional programming problem to a single objective fuzzy linear fractional programming problem and ﬁnd its fuzzy optimal solution which inturn yields a fuzzy Pareto optimal solution for the given fully fuzzy multi-objective linear fractional programming problem. To demonstrate the proposed strategy, a numerical example is provided.
A Modified Chi-square Type Test for Distributional Validity with Applications to Right Censored Reliability and Medical Data
Authors: M. Yousof Haitham , Al-nefaie Abdullah H. , Aidi Khaoula , Ali M. Masoom , Mohamed Mohamed ibrahim
Published: December 2021

In this paper, a modified Chi-square goodness-of-fit test called the modified Bagdonavičius-Nikulin goodness-of-fit test statistic is investigated and the applied for distributional validation under the right censored case. The new modified goodness-of-fit test is presented and applied for the right censored data sets. The algorithm of the censored Barzilai-Borwein is employed via a comprehensive simulation study for assessing validity of the new test. The modified Bagdonavičius-Nikulin test is applied to four real and right censored data sets. A new distribution is compared with many other competitive distributions under the new modified Bagdonavičius-Nikulin goodness-of-fit test statistic.
Engineering of the fiber optic Bragg grating sensor of electrical parameters and software application for automatic simulation of its parameters
Authors:   Samara National Research University, 34 Moskovskoe Shosse, 443086, Samara, Russia, Leonovitch Georgy I. , Zakharov Valery N. ,   Samara National Research University, 34 Moskovskoe Shosse, 443086, Samara, Russia, Gorshkov Aleksandr I. ,   Samara National Research University, 34 Moskovskoe Shosse, 443086, Samara, Russia
Published: December 2021

Nowadays one of the most effective transducer rised to the high demands based on metrological and exploitative characteristics are fiber optical. In the article there is modern state of measurement fiber optical sensors. Basic types and methods of measurement are examined. New model of fiber optic Bragg grating sensor for measurement of electric parameters is suggested. For the suggested model a program for computing the parameters of sensor is written, valid model is presented on experimental board. The results of the work and their valuating are received.
Ab initio modeling of optical properties of the new sp3 silicon and germanium allotropes
Authors:   Samara National Research University, 34 Moskovskoe Shosse, 443086, Samara, Russia, Saleev Vladimir A. , Shipilova Alexandra V. ,   Samara National Research University, 34 Moskovskoe Shosse, 443086, Samara, Russia
Published: December 2021

The application of the hybrid topological-quantum-mechanical method to the search of new allotropes of 14th group elements is demonstrated for silicon and germanium. Starting from the databases of hypothetical and real zeolite nets and subsequently apllying the geometrical and energetic selection criteria, we extract the most energetically favourable structures for the allotropic modifications of silicon and germanium, and study their optical properties. In the framework of density functional theory we calculate the frequency-dependent complex dielectric tensors, refraction and absorption coefficients of the selected allotropes and their electronic band gaps.
Mathematical modeling of separation of watered oil-containing mixture
Authors:   Samara National Research University, 34 Moskovskoe Shosse, 443086, Samara, Russia, Zelenskiy Vladimir A. , Sushin Aleksandr A. ,   Samara National Research University, 34 Moskovskoe Shosse, 443086, Samara, Russia, Shchodro Artyom I. ,   Samara National Research University, 34 Moskovskoe Shosse, 443086, Samara, Russia
Published: December 2021

A mathematical description of the separation process of the watered oil-containing mixture has been proposed. The mathematical model is based on the determination of the speed of movement of oil globules in a constrained flow. The formula for determining the velocity of the globules is derived from theoretical provisions and experimental data. The key issue of simulation is determining the separation time. This characteristic is calculated as a time period from the moment of arrival of the portion of oil-containing mixture to the first chamber of the separator to the moment of formation of the continuous phase layer of the given thickness on the surface. The mathematical model enables us to determine the separation time taking into account geometric characteristics of the separation device at the high level of water content. Thus, a topical problem of improving the performance of the separation device without sacrificing the quality of the commercial oil is solved.
Various aspects of liquid and gas pressure metering in problems of statics of flexible bars
Authors: Ovchinnikov N.T.
Published: December 2021

In some practical applications, bars are loaded with the pressure of liquids and gases. Although the work of such objects is well studied and described in a large number of papers, some of the latter have wrongful provisions. For example, the equilibrium equations of a pipeline often include axial force instead of equivalent force, which reduces the accuracy of estimating the bending shape and acting stresses. The problem of accounting for pressure is due to the objectively more complex type of this loading in comparison with the forces of weight and insufficient distribution of the known provisions in engineering. This review and methodological paper focuses on a set of issues related to the loading of a bar by pressure. In the research, first, we obtained vector and linearized equations of equilibrium of the bar taking into account the load from the surface pressure. Then, we substantiated the equivalence of loading the bar with pressure and weight load determined by Archimedes’ law. Finally, we gave provisions for taking into account the pressure in the study of the equilibrium, stability, deformation, and strength of the bar. As an example, the effect of pressure in the problems of laying a pipeline on the seabed and evaluating the longitudinal stability of the bar is shown.
Change in the acoustic anisotropy parameter of structural steel during fatigue failure
Authors: Sergeeva O.A. , Gonchar A.V.
Published: December 2021

Material damages affect its microstructure, physical and acoustic properties. The article considers microstructural and ultrasonic studies of the St3sp5 steel carried out under cyclic uniaxial tension-compression in the low-cycle fatigue area. The fatigue tests were performed in stages. At each stage of cyclic deforming, the structure of steel samples was studied by the ultrasonic method and the change in the acoustic anisotropy parameter was determined. The relationship between the acoustic characteristics of the material and the degree of its damage is found. Based on the relationship the residual life can be predicted. The advantage of this method for determining the residual resource using the acoustic anisotropy parameter is that it is not required to determine the length of the acoustic path, for example, the wall thickness of the object under study. The influence of the deformation range of the cycle on the rate of the acoustic anisotropy parameter change is investigated. A direct linear relationship was established between the relative number of cycles and acoustic anisotropy parameter. An algorithm for determining the residual life of a material based on studies of microstructural changes and ultrasonic data is proposed.
Application of precision chronometric technologies for monitoring deviations in the internal combustion engine operation
Authors: Plaksina E.T. , Syritsky A.B. , Komshin A.S.
Published: December 2021

The article considers the main methods of internal combustion engine diagnostics. A method based on measuring the time intervals between the phases of the working cycle of the mechanism is described. An algorithm for measuring the time intervals from the formulation of the problem to the proof of the efficiency of this method on an internal combustion engine has been determined. The installation of the angle sensor on the crankshaft of the experimental bench engine VAZ 21126 is shown. The basis for the construction of a mathematical model of the crankshaft is presented and the main factors influencing its movement are identified. A criterion has been established according to which the misfire is determined most accurately. The results obtained can be used for developing diagnostic systems for internal combustion engines, as well as engines operating in extreme conditions, for example, beyond the Arctic Circle, on ships, etc.
Investigation of the structural and functional reliability of the motion control and navigation system of a small spacecraft in the conditions of its multi-mode operation
Authors: Pavlov A.N. , Pavlov D.A. , Kulakov A.Yu. , Umarov A.B.
Published: December 2021

In the course of the design, creation and application of complex multi-mode systems, which undoubtedly include the motion control system of small spacecraft for remote sensing of the Earth, when choosing the configuration of elements and connections between them, as well as the parameters of the system, it is advisable to explore the possibilities of using dynamic operation modes significantly affecting the structural and functional reliability of the system. Based on the new original concept of the parametric genome of the complex multi-mode object structure, introduced by the authors, the article describes the results of the studies of the influence of various options for activating the modes of operation on the structural and functional reliability of the motion control and navigation system of the small spacecraft “Aist-2D”. To assess the structural and functional reliability of the system under study integral indicators have been introduced. At the same time, the possibility of involving joint activation of the modes of operation, the equivalence of the intensities of utilizing the activation of the modes of operation and the homogeneity of the traffic control system were taken into account.
On the use of light sensors on CubeSat nanosatellites
Authors: Kolesnikova M.A. , Nikolaev P.N. , Kramlikh A.V.
Published: December 2021

The paper focuses on the usage of the TCS34725 light sensor in the motion control system of the SamSat-Science nanosatellite platform. The sensor is designed to determine the angle between the sensor normal and the direction to the light emitter center. We developed a technique for calibrating light sensors, carried out a series of experiments, verified the nominal characteristic of the light sensor, and found the dependency of mean squared deviation (MSD) of the sensor values on the angle of incidence of the light flux. Three layouts of light sensors on the lateral faces of the nanosatellite are considered: on a plane; on the faces of a quadrangular pyramid with an inclination angle of 45°; on the faces of a truncated quadrangular pyramid with an angle of inclination of 45°. We have chosen a circuit that provides measurements with minimum noise.
Persistent Eustachian valve and transient arterial hypoxemia in a newborn: a clinical observation
Authors: Tarayan M. V. , Drozdova I. A. , Bondareva I. O. , Efremov E. S. , Vishnyakova M. V.
Published: December 2021

The Eustachian valve (EV) is located in the orifice of inferior vena cava and belongs to structures of the normal heart. It plays an important role in the fetal blood flow by directing the flow of blood from inferior vena cava through an open foramen ovale to the left atrium, thereby ensuring the systemic flow in a fetus and bypassing the pulmonary circulation. After birth and upon closure of the foramen ovale, the valve ceases to function and tends to regress. Usually, a prominent EV is a clinically non-significant ultrasound finding. In isolated cases, however, it can cause significant hemodynamic abnormalities and subsequent rhythm disorders, delayed fetal development and transient hypoxemia in newborns. It can extremely rare be a cause of blood right-toleft shunting through the foramen ovale leading to desaturation. Clinically it can manifest by central cyanosis in newborns and infants. The differential diagnosis is made in neonatal intensive care units. We present a  case of transient arterial hypoxemia in a  newborn with prominent EV and inter-atrial shunt. A  one-month old infant was transferred from the Department of Pediatric Cardiology with a  history of transient hypoxemic spells related to right-to-left shunting via atrial septal defect caused by obstruction of the tricuspid valve by the prominent EV. The instrumental findings including contrast-enhanced tomography supported this hypothesis. The patient was stable for subsequent 10 days of the follow-up, which allowed for further conservative managements until the conventional time point for children with an atrial septal defect. Potential regress of the prominent EV, as well as natural growth of an infant and his/hers intracardiac structures, provide mostly favorable outcome without a surgical intervention. This was clearly illustrated in the clinical case.