bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN TINGKAT STRES DENGAN KEJADIAN HIPERTENSI PADA USIA DEWASA AWAL (18-40 TAHUN)
Authors: Halawa Aristina , Artini Budi , Manutmasa Yustina Santina
Published: January 2024

Stres pada dewasa awal akan mengalami gejala fisik seperti menciptakan perubahan dalam metabolisme, meningkatkan laju detak jantung dan pernafasan, meningkatkan tekanan darah atau menimbulkan sakit kepala yang luar biasa, serta menyebabkan serangan jantung bahkan mengalami strok. Tujuan: penelitian ini untuk menganalisis hubungan tingkat stres dengan kejadian hipertensi pada usia dewasa awal. Metode penelitian yang digunakan adalah korelasi dengan metode pendekatan cross sectional, populasi dalam penelitian ini sebanyak 66 orang, besar sampel 57 orang dipilih menggunakan teknik Simple Random Sampling. Pengumpulan data menggunakan kuesioner dan lembar observasi. Hasil penelitian menunjukkan sebagian besar responden mengalami tingkat stres sedang yaitu 30 orang (52,6%) dan untuk Hipertensi paling banyak mengalami pre hipertensi sebanyak 22 orang (38,6%). Hasil uji spearman didapatkan p=0.003 dengan kemaknaan p<0.005 yang berarti H1 diterima. Kesimpulan: hal ini menunjukkan bahwa terdapat hubungan antara tingkat stres dengan kejadian hipertensi pada dewasa awal. Berdasarkan hal tersebut tekanan darah pada dewasa awal dapat dikontrol dengan menjaga gaya hidup sehat agar tidak mengalami stres.
PELATIHAN KEMANDIRIAN IBU DALAM PENANGANAN KONDISI KEGAWATDARURATAN PADA ANAK DI PERUMAHAN GODEAN JOGJA HILLS SLEMAN YOGYAKARTA
Authors: Pujiastuti Diah , Sari Ignatia Yunita , Prawesti Indah , Indrawati Nining
Published: January 2024

Gawat merupakan kondisi yang mengancam nyawa sedangkan darurat berarti kondisi yang perlu penanganan segera untuk menghilangkan ancaman nyawa korban. Kondisi gawat darurat tidak hanya terjadi di tempat-tempat yang ramai tetapi juga dalam lingkungan pemukiman warga atau perumahan warga. Urgensi dari permasalahan kegawatdaruratan pada anak dapat menyebabkan kematian, sangat perlu untuk dilakukan edukasi terkait penanganan kegawatdaruratan pada anak. Kegiatan ini sebagai salah satu upaya penanganan dan mengurangi mortalitas kasus kegawatdadruratan pada anak yang meliputi kasus tersedak, kasus luka bakar, dan demam harus diperhatikan dari berbagai aspek karena pada proses perawatannya membutuhkan biaya pengobatan yang sangat banyak, perawatan yang lama, hingga operasi berulang kali. Sekalipun dapat pulih, bisa saja menimbulkan kecacatan yang menetap seumur hidup bahkan kematian. Kegiatan pelatihan dilakukan melaui tahapan pre-test, pelatihan, dan post-test serta evaluasi. Pre-test dilakukan dengan membagikan kuesioner kepada ibu-ibu. Pelatihan dibagi menjadi 2 tahap yaitu tahap 1 penyampaian materi tentang penanganan kegawatdaruratan anak menggunakan media power point, dan tahap ke-2 demonstrasi menggunakan alat peraga (pantom bayi, handuk, thermometer). Post-test dilakukan dengan membagikan kuesioner yang sama dengan pre-test kepada ibu-ibu. Tahap evaluasi dilakukan selama 2x evaluasi, bekerjasama dengan kader dan grup pelatihan untuk melakukan observasi secara berkala dalam kemampuan memahami dan mengingatkan prosedur penanganan kegawatdaruratan tersebut. Kegiatan pelatihan ini berhasil meningkatkan pemahaman dan keterampilan ibu sebesar 3,5 dari skor rerata sebelum pelatihan 4,25 menjadi 7,75 setelah pelatihan. Kegiatan ini juga meningkatkan kemampuan ibu dalam mengatasi serta lebih dapat mandiri dalam melakukan penanganan kegawatdaruratan dirumah, khususnya kegawatdaruratan pada anak.
UPAYA PENCEGAHAN HIPERTENSI PADA LANSIA MELALUI PENYULUHAN KESEHATAN, SENAM DAN PEMBERIAN JUS TIMUN DI KELURAHAN BUBUTAN SURABAYA
Authors: Siagian Martha Lowrani , Laitama Nurmawati S. , Widari Ni Putu , Devika Kurnia
Published: January 2024

Hipertensi adalah salah satu penyakit tidak menular (PTM) yang dapat menyerang siapa saja, baik muda maupun tua. Urbanisasi yang cepat, gaya hidup, junkfood, dan stress merupakan faktor risiko yang bertanggung jawab untuk terjadinya peningkatan prevalensi hipertensi. Hipertensi merupakan masalah kesehatan yang banyak dijumpai pada lansia dan perlu adanya penanganan yang tepat seperti pelaksanaan latihan fisik pada lansia dan peran keluarga untuk membantu lansia mengatasi masalah tersebut. Tujuan dari pengabdian masyarakat ini adalah Meningkatkan kesadaran lansia terhadap penyakit hipertensi untuk meningkatkan kualitas hidup pada lansia, dapat mendemonstrasikan senam lansia yang diberikan untuk membantu menurunkan tekanan darah, serta dapat mencegah terjadinya hipertensi dengan mengkonsumsi jus mentimun secara rutin. Metode yang dilakukan adalah penyuluhan kesehatan, melakukan senam hipertensi dan membagikan minuman jus mentimun. Kegiatan pengabdian masyarakat berupa pencegahan hipertensi melalui penyuluhan kesehatan, senam lansia dan pemberian jus mentimun berlangsung dengan baik dengan hasil terdapat peningkatan pengetahuan antara sebelum dan sesudah diberikan edukasi. Kegiatan ini sangat bermanfaat untuk membentuk kebiasaan baik dalam upaya pencegahan hipertensi, melalalui pemeliharaan kesehatan dengan rutin berolahraga dan mengkonsumsi jus timun. Kegiatan ini dapat diaplikasikan oleh peserta didalam kehidupan sehari-hari sehingga kejadian hipertensi dapat dicegah.
PEMANFAATAN BUAH PISANG SEBAGAI TERAPI NON FARMAKOLOGIS DAN KEARIFAN LOKAL DALAM UPAYA PENCEGAHAN PREEKLAMSIA KEHAMILAN
Authors: Tono Sendy Firza Novilia , Aprilia Devi
Published: January 2024

Kematian ibu di Indonesia masih didominasi oleh tiga penyebab utama yaitu perdarahan, hipertensi dalam kehamilan (HDK), dan infeksi. Preeklampsia dan eklampsia merupakan penyebab utama mortalitas dan morbiditas ibu dan bayi. Insiden preeklampsia adalah 7-10% dari kehamilan dan merupakan penyebab kematian ibu nomor dua di Indonesia. Dalam penatalaksanaan preeklampsia upaya yang dilakukan berupa upaya nonfarmakologis (memodifikasi gaya hidup melalui pendidikan kesehatan) dengan memanfaatkan buah pisang sebagai upaya terapi nonfarmakologis dalam pencegahan preeklamsia. Tujuan kegiatan pengabdian ini adalah untuk meningkatkan pengetahuan kesehatan kepada masyarakat. Pelaksanaan kegiatan ini berupa penyuluhan  dan edukasi cara mengonsumsi dan memadukan dengan gaya hidup berolaraga. Penyuluhan dilakukan dengan memberikan materi seputar preeklampsia dan bahayanya dan penatalaksanaannya. Penilaian untuk mengetahui tingkat pengetahuan peserta dilakukan sebanyak 2 kali, yaitu dilakukan pre-test dan post-test. Hasil dari kegiatan pengabdian ini didapatkan bahwa saat pre-test sekitar 75% ibu hamil mengetahui tentang preeklampsia dan bahayanya. Setelah dilakukan penyuluhan kesehatan, terjadi peningkatan secara signifikan tingkat pengetahuan Sebagian besar bidan menjadi 100%.
PEDULI KESEHATAN IBU HAMIL DI MASYARAKAT MELALUI LATIHAN KOMBO YOGA ROMLA (KOMBINASI YOGA DAN AROMATERAPI LAVENDER) DAN DETEKSI KOMPLIKASI IBU HAMIL
Authors: Rhomadona Shinta Wurdiana , Tono Sendy Firza Novilia , Rahayu Asti
Published: January 2024

Upaya percepatan penurunan AKI telah  dilakukan dengan menjamin agar setiap ibu mampu mengakses pelayanan kesehatan yang berkualitas, namun sayangnya cakupan pelayanan kesehatan ibu hamil K6 di Jawa Timur masih rendah yaitu 58,7%. Kondisi tersebut mengambarkan masih banyak ibu hamil yang belum mendapatkan pelayanan secara komprehensif. Puskesmas Gunung Anyar adalah salah satu Puskesmas yang dijadikan pilot projek Dinkes Kota Surabaya dalam upaya menurunkan AKI karena masih ditemukannya kematian ibu di sana. Walaupun hanya 1 kematian, namun tidak ada toleransi selama masih ada AKI. Hasil penelusuran ke Posyandu diketahui bahwa belum ada integrasi kegiatan Posyandu dengan pemeriksaan kehamilan, kemudian kesadaran untuk rutin memeriksakan diri dan cek laboratorium juga masih rendah. Selain itu banyak ibu hamil disana yang memiliki gangguan tidur terlihat dari keluhan saat ANC, padahal kurang tidur pada ibu hamil dapat menyebabkan efek samping yang membahayakan ibu dan janin. Upaya-upaya untuk mengatasi kesulitan tidur bisa dilakukan dengan yoga dan aromaterapi bahwa cara tersebut dapat membuat rileks sehingga dapat memperbaiki kualitas tidur ibu hamil tersebut. Berdasarkan masalah tersebut, maka perlu dilakukan beberapa upaya menurunkan AKI melalui PkM dengan mengadakan kegiatan yaitu “Peduli Kesehatan Ibu Hamil di Masyarakat Melalui Latihan “Kombo Yoga Romla” (Kombinasi Yoga dan Aromaterapi Lavender) dan Deteksi Komplikasi Ibu Hamil”. Tujuan kegiatan ini adalah meningkatan pengetahuan, kualitas tidur, dan kesehatan ibu hamil sebagai deteksi komplikasi kehamilan sehingga diharapkan dapat menekan AKI. Hasil dari kegiatan ini adalah terjadi peningkatan kualitas tidur ibu hamil dari 26,7% yang memiliki kualitas tidur baik menjadi 86,7% setelah diberikan latihan kombo yoga romla. Terjadi peningkatan pengetahuan rata-rata dari 31,1% berpengetahuan baik menjadi 86,7%.
PELATIHAN PIJAT BAYI SEBAGAI UPAYA OPTIMALISASI TUMBUH KEMBANG ANAK DI WILAYAH KERJA PUSKESMAS HITU KABUPATEN MALUKU TENGAH
Authors: Fauziah Siska Febrina , Lestaluhu Viqy , Masi Siti Jubaeda
Published: January 2024

Malnutrisi pada bayi dan balita dampaknya luas, sifatnya permanen dan tidak bisa diperbaiki. Rendahnya pemahaman orang tua terkait dengan pemantauan pertumbuhan anak merupakan salah satu penyebab meningkatnya angka malnutrisi dikarenakan tindakan koreksi yang terlambat atau bahkan terabaikan. Oleh karena itu, tim pengabdi memandang penting pemberian edukasi terkait pertumbuhan dan perkembangan anak serta pelatihan pijat bayi bagi kader dan ibu yang memiliki balita sebagai upaya optimasilasi tumbuh kembang anak. Kegiatan pengabdian kepada masyarakat ini dilaksanakan di wilayah kerja Puskesmas Hitu, Kabupaten Maluku Tengah pada bulan Juni – Agustus 2023. Sasaran kegiatan ini adalah kader dan ibu yang memiliki balita sebanyak 30 orang. Pelatihan pijat bayi diselenggarakan selama dua hari. Pada hari pertama, peserta kegiatan diminta untuk mengisi pre-test sebelum pemberian materi. Adapun materi yang disampaikan antara lain edukasi terkait pentingnya pemantauan pertumbuhan dan perkembangan balita, serta demonstrasi pijat bayi. Peserta kegiatan difasilitasi untuk melakukan diskusi tanya jawab dan praktik pijat bayi pada phantom. Pada hari kedua, peserta kegiatan dibagi menjadi 3 kelompok dan masing-masing kelompok didampingi oleh satu orang tim pengabdi untuk melakukan pijat bayi. Di sesi terakhir, peserta kegiatan diminta untuk mengisi post-test. Kegiatan dilanjutkan dengan monitoring dan evaluasi pelaksanaan pijat bayi dan pemantauan pertumbuhan balita sasaran oleh peserta kegiatan. Target kegiatan ini dapat tercapai sesuai rencana, di mana terdapat peningkatan pemahaman sasaran terkait pertumbuhan dan perkembangan anak, peningkatan keterampilan sasaran dalam melakukan pijat bayi, dan peningkatan berat badan balita sasaran.
PERAN SATGAS TB MELALUI EDUKASI PENCEGAHAN TB DI MASYARAKAT WILAYAH KECAMATAN SAWAHAN SURABAYA
Authors: Sari Ethyca , Aprilia Devi
Published: January 2024

Satgas Penanggulangan Tuberkulosis (Tb) mempunyai peran antara lain mendampingi pasien mengakses pengobatan serta mengatasi segala permasalahan sosial yang dihadapi pasien. Termasuk pula memberikan intervensi terhadap lingkungan tempat tinggal pasien apabila rumahnya tidak layak huni serta memberikan edulkasi secara berkesianmbungan dalam meningkatkan pengetahuan masyarakat dalam merubah perilaku pencegahan Tb. Tujuan pengabdian masayakat ini adalah untuk membantu masyarakat lebih menyadari pentingnya mencegah penularan Tb yang ada di sekitar lingkungannya. Metode   yang   digunakan   dalam   pengabdian   ini   adalah   penyuluhan kesehatan   dengan   media leaflet  dan Pre Test dan Post Test dengan jumlah warga masayarakat 50 orang. Hasil dari pre test dan post test di dapat adanya peningkatan pemahaman dan pengetahuan masyarakat dalam penularan serta  pencegahan  penyakit  TB Paru.  Yang  mana  tingkat  pemahaman   sebelumnya  sebesar    64 % setelah dilakukan penyuluhan  tingkat  pemahaman masyarakat   naik  menjadi  80%  terhadap  penularan  dan pencegahan Tb.
E-mpowering Learning: Innovating Entrepreneurship Education through Digital Media Inclusion and Digipreneur Approach at Andikpas LPKA Class I Palembang
Authors: Martini Rita , Sayuti A. Jalaludin , Simanjuntak Tiur , Febrianty Febrianty , Ajismanto Fahmi , Barovih Guntoro
Published: January 2024

This study aims to develop E-Mpowerment learning media that involves the inclusion of Digipreneur entrepreneurship at Andikpas LPKA Class I Palembang. The development method used is the ADDIE model (Analysis, Design, Development, Implementation, Evaluation). The study involves education experts, entrepreneurship experts, and students of Andikpas LPKA Class I Palembang as respondents. The result of the development of E-Mpowerment learning media is an interactive digital platform that provides entrepreneurship learning materials tailored to the needs of students at Andikpas LPKA Class I Palembang. The platform is equipped with interactive learning features such as instructional videos, business simulations, and interactive quizzes. Additionally, the platform provides content that can be accessed independently by students and supports Digipreneur entrepreneurship inclusion. This study has generated positive feedback from education experts, entrepreneurship experts, and students. They stated that the E-Mpowerment learning media is effective in improving students' understanding of entrepreneurship concepts, digital skills, and learning motivation. Furthermore, Digipreneur entrepreneurship inclusion provides opportunities for students to develop creativity, innovation, and an entrepreneurial mindset. In conclusion, this study has successfully developed effective E-Mpowerment learning media to enhance entrepreneurship skills among students at Andikpas LPKA Class I Palembang. This learning media provides an interactive and inclusive learning experience through the Digipreneur entrepreneurship approach. It is hoped that this research can serve as a reference for the development of innovative and technology-relevant learning media in the context of entrepreneurship education.
Halal Food Market Based on the Meaning of Alumni of Shariah Economic Major at University in Samarinda and Makassar
Authors: Maulida Rizky , Gafur Abdul
Published: January 2024

This study aims to formulate the halal food market based on an interpretation of the contemporary conditions of the halal food market. Data was collected through interviews with 3 (three) informants who are alumni of the shariah economic major at university in Samarinda and Makassar. The implementation of data analysis uses an interactive model data analysis component approach. This study concludes that the halal food market is a market consisting of the intentions, worship, and falah of market participants. A strong intention is manifested in the form of repentance, while worship is through honesty, generosity, fairness, and responsibility to achieve falah for market participants, namely the formation of trust, blessing, and safety.
Modified Chalcogenide Glass Equations for the Activation Energy of Crystallization
Authors: Loretz Richard A. , Loretz Thomas J.
Published: January 2024

For over six decades, chalcogenide glasses (ChGs) have played a pivotal role in the optical community, fostering innovations and new applications in photonics, electronics, and electro-optics. In the last decade, the exploration of novel applications, such as Gradient Index (GRIN) ChGs, has underscored the need for a nuanced comprehension and precise control of nucleation and crystallization kinetics in emerging infrared glass compositions. This article explores the activation energy of crystallization in amorphous materials, particularly focusing on ChGs. It identifies long-standing challenges associated with existing models used for crystal growth in nucleated glasses. Employing carefully outlined mathematical logic, our study critiques conventional models and introduces innovative equations centering around the need for balanced units and proper physical trends. These new models overcome some shortcomings of the established framework and provide a more accurate depiction of crystallization kinetics. To validate the efficacy of our proposed models, we conducted a comparative analysis using differential scanning calorimetry data from a recently published Sb-Te-Se chalcogenide glass composition. The numerical and graphical results clearly illustrate the improvements inherent in our models and their practical utility. Beyond ChGs, our models and equations have broader applications. They may extend to oxide, halide, oxy-halide, and fluoride glass compositions, as well as polymers, contributing new tools to the understanding of crystallization kinetics across diverse materials.
 
Received: 29 November 2023 | Revised: 9 January 2024 | Accepted: 18 January 2024
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
Data sharing not applicable – no new data generated. All data used in calculations was extracted from Elabbar et al. (2008).
Centering indigenous knowledge through multimodal approaches in English first additional language learning
Authors: Machimana Petronella Nondumiso Nompilo , Genis Gerhard
Published: January 2024

In this article, we address findings from a study conducted with high school learners in Gauteng, South Africa. It explored the strategies used by learners when learning English as a First Additional Language (EFAL). We used a conceptualisation of Ubuntu as a lens through which to explore EFAL learning. Data collection included an open-ended questionnaire and non-participant observation. Participants were purposefully sampled from peer-tutoring organisations around Gauteng. The key findings, which include the use of indigenous poetry, dance and storytelling by learners, highlight the need to include indigenous practices in the language classroom. Learners also showed a preference for cooperative learning and for using humour as a strategy for EFAL learning. We argue that the silencing of indigenous knowledge systems (IKS) perpetuates epistemic violence by limiting the resources available for learning. Therefore, more should be done in the EFAL classroom to ensure the inclusion of IKS. Through the findings of this study, we propose that including Ubuntu values and IKS in the curriculum is imperative if educational outcomes are to be improved, as these systems allow learners to become more involved and engaged in their own learning. This will re-centre African voices and valorise indigenous epistemologies.
Núcleo Pedúnculo Pontino
Authors: Piedimonte Fabián C. , Acosta Tania
Published: January 2024

Algunos trastornos motores, principalmente la enfermedad de Parkinson (EP) avanzada y la parálisis supranuclear progresiva, así como diversos signos y síntomas son refractarios al tratamiento farmacológico y a las estrategias quirúrgicas clásicas, como los trastornos de la marcha, la inestabilidad postural y las caídas a repetición. Evidencia reciente sugiere que el Núcleo Pedúnculo Pontino (NPP), más ampliamente la “Región Locomotora Mesencefálica”, está involucrado en la génesis de dichos trastornos.
Incubadoras acreditadas y su efecto en la creación de emprendimientos en el Ecuador
Authors: Morales-Morejón Silvia , Álvarez-Peña Marta , Castañeda-Junco Rina
Published: January 2024

El emprendimiento es indispensable para brindar oportunidades de un mejor nivel de vida para las sociedades y dado que las incubadoras tienen la función de potencializarlos a fin de lograr su generación, expansión o aceleración. En Ecuador, este es un tema todavía nuevo aún y existen un total de 26 incubadoras acreditadas y distribuidas en 6 provincias con directa injerencia de las Instituciones de Educación Superior (IES). Esta investigación tiene como propósito determinar las características de las incubadoras ecuatorianas acreditadas, identificando el tipo de incubadoras y su influencia en la expansión de emprendimientos en sus provincias de origen. La investigación utilizó datos cuantitativos y cualitativos, la información cuantitativa responde a un total de 26 incubadoras acreditadas y 9933 emprendimientos originados durante el cuarto trimestre del año 2021 hasta el segundo trimestre del año 2023.  La información cuantitativa fue analizada a través de la prueba de Shapiro-Wilk, mientras que los datos cualitativos hacen referencia a servicios que ofrecen las incubadoras, principalmente. Los resultados muestran que las incubadoras ecuatorianas ejercen una influencia positiva en la generación de emprendimientos, existiendo una correlación moderada entre estas variables, respecto al tipo de incubadoras es posible identificar que en Ecuador existen dos tipos de incubadoras, las de primera y segunda generación, la mayoría de estas incubadoras ofrecen servicios de consejería y asesoría, mientras que sólo tres ofrecen capital semilla a los emprendedores.  Estos aspectos muestran que tienen un efecto parcial en la generación de emprendimientos en sus provincias respectivas.
Technical Note: Considerations to Avoid Corrosion Rate Estimate Error of the Reinforcing Steel if Based Only on Concrete’s Electrical Resistivity
Authors: Torres-Acosta Andrés A.
Published: January 2024

In recent years, the use of electrical resistivity (ρ) of concrete as a design parameter has intensified, ranging from its use as a durability index in laboratories for the characterization of cement-based materials, as well as in inspection of existing structures, to diagnose the pathological problems they present. It has also been used as a durability index to accept or reject a concrete mixture during the construction of concrete infrastructure that it should comply as a durable concrete mixture. ρ of concrete has also been used as an indirect measure of the corrosion rate (icorr) of the embedded steel in concrete to determine not only the time of corrosion initiation but also the propagation time of corrosion of reinforcing or prestressing steel. This allows indirect measurements of icorr from ρ measurements on the concrete surface without the need to connect the reinforcing or prestressing steel to the measuring equipment. The present investigation presents some results from the literature that corroborate this direct correlation between ρ of concrete and icorr of the embedded steel for some exposure conditions, and some considerations are discussed to avoid possible measurement interpretation errors if this correlation is used in real structures.
Tradisi Baritan Masyarakat Muslim Pedesaan Wonosobo: Dialektika Komunitas-Struktur Perspektif Victor Turner
Authors: Muhammad Yusuf  , Sri Rahayu  , Muhammad Amin
Published: January 2024

This paper aimed to reveal the meaning and relationship of community-structure dialectics through the Baritan tradition carried out by Muslim communities in Jojogan Village, Parikesit Village, Patak Banteng Village, Wonosobo Regency. The participants in this research are Muslim communities in Jojogan Village, Patak Banteng Village, and Parikesit Village who carry out the Baritan tradition. Participants in the community were classified into ordinary people, community leaders, religious leaders, and village officials. The data collection technique was carried out by collecting research data obtained through interviews and observation methods. The results showed that in the tradition there are symbols that build egalitarian social relations where individuals merge and release their social status and these symbols have meanings that are understood together. The symbols and meanings can be seen in the activities of cleaning springs, praying together, and alms which are a series of Baritan tradition ceremonies. Second, the Baritan tradition is a form of community resistance to the life of the general public that creates a hierarchical structure or relationship in social life which is considered to eliminate or threaten the way of life that is in accordance with local values.
ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ CÓ ĐỘT BIẾN GEN EGFR HOẶC ALK DI CĂN NÃO BẰNG XẠ PHẪU GAMMA KNIFE KẾT HỢP TKIS THẾ HỆ 1 TẠI BỆNH VIỆN K
Authors: Phạm Hồng Phúc , Nguyễn Đức Liên , Phan Thanh Dương , Nguyễn Minh Thuận
Published: January 2024

Ung thư phổi là một trong những bệnh ác tính hay gặp nhất và là nguyên nhân tử vong hàng đầu do ung thư trên thế giới. Trong những bệnh nhân UTP KTBN, bệnh nhân di căn não có tỷ lệ độ biến gen EGFR cao hơn so với bệnh nhân không có di căn não và ngược lại, trong những BN UTP KTBN có đột biến gen, tỷ lệ di căn não (70%) vượt trội tỷ lệ di căn não trong nhóm khôn có đột biến gen EGFR. Trước đây, di căn não được biết đến là yếu tố tiên lượng xấu, tuy nhiên với sự tiến bộ của y học, đặc biệt là sự ra đời của thuốc điều trị đích và xạ phẫu đã cải thiện đáng kể kết quả điều trị bao gồm cả sống thêm và kiểm soát triệu chứng. Nghiên cứu của chúng tôi nhằm mục tiêu đánh giá kết quả điều trị ung thư phổi không tế bào nhỏ có đột biến gen EGFR hoặc ALK di căn não bằng xạ phẫu Gamma Knife kết hợp TKIs thế hệ 1. Đối tượng và phương pháp nghiên cứu: Chúng tôi tiến hành nghiên cứu mô tả trên 44 bệnh nhân ung thư phổi không tế bào nhỏ có đột biến gen EGFR hoặc ALK di căn não từ tháng 7/2019 đến 6/2023. Bệnh nhân được lựa chọn di căn não từ 1 – 10 ổ, đường kính lớn nhất mỗi ổ ≤ 3 cm, chỉ số toàn trạng Karnofsky ≥ 60, có đột biến EGFR hoặc ALK, điều trị TKIs thế hệ 1 pha đầu. Bệnh nhân được xạ phẫu bằng máy Gamma Knife thế hệ Icon với liều chỉ định 20 – 24 Gy với khối u < 2cm, 18 – 20 Gy với khối u 2 – 3 cm. Bệnh nhân điều trị TKIs thế hệ 1 (erlotinib hoặc gefitinib hoặc crizotinib) 1 viên/ngày. Bệnh nhân được đánh giá đáp ứng triệu chứng lâm sàng và hình ảnh theo tiêu chuẩn RANO mỗi 6 tháng, và kết quả sống thêm. Kết quả: Trong nghiên cứu của chúng tôi, tỷ lệ sống thêm không tiến triển tại não tại 12 tháng là 94,8%, 24 tháng là 51,7%. Tỷ lệ sống thêm toàn bộ tại 12 tháng là 83,9%, 24 tháng là 58,6%, 3 năm là 39,1%, trung vị thời gian sống thêm toàn bộ là 28 tháng ± 3,3 tháng. Kết luận: Xạ phẫu Gamma Knife kết hợp TKIs thế hệ 1 là một phương pháp điều trị hiệu quả đối với tổn thương di căn não của ung thư phổi không tế bào nhỏ có đột biến gen EGFR hoặc ALK.
CHỌN LỰA PHƯƠNG PHÁP PHỤC HỒI LƯU THÔNG RUỘT SAU PHẪU THUẬT NỘI SOI CẮT PHẦN XA DẠ DÀY: NHẬN ĐỊNH VỀ MẶT CHỨC NĂNG
Authors: Đặng Quang Thông , Trần Quang Đạt , Đoàn Thùy Nguyên , Hồ Lê Minh Quốc , Nguyễn Viết Hải , Nguyễn Vũ Tuấn Anh , Nguyễn Hoàng Bắc , Võ Duy Long
Published: January 2024

Đặt vấn đề: Phục hồi lưu thông (PHLT) sau phẫu thuật cắt phần xa dạ dày (CPXDD) vẫn còn nhiều tranh cãi. Nghiên cứu hồi cứu này được thực hiện để đánh giá hiệu quả về mặt chức năng của 5 phương pháp PHLT sau sau phẫu thuật CPXDD. Đối tượng và phương pháp nghiên cứu: Nghiên cứu hồi cứu trên 426 bệnh nhân ung thư biểu mô tuyến dạ dày được phẫu thuật nội soi (PTNS) CPXDD từ 2017 đến 2020 tại Bệnh viện Đại học Y Dược TP. Hồ Chí Minh. Năm phương pháp PHLT bao gồm: Billroth 1 (B-I), Billroth 2 kiểu delta (B-II-ds), Billroth 2 với miêng nối Braun (BII Braun), Billroth 2 khâu treo quai đến (B-II-h) và Roux-en-Y (R-Y). Kết quả ngắn hạn bao gồm các đặc điểm phẫu thuật và tỉ lệ biến chứng. Kết quả lâu dà gồm kết quả nội soi sau 1 năm theo phân loại LA và phân loại RGB. Kết quả: PHLT kiểu B-II Braun hoặc R-Y có thời gian phẫu thuật dài hơn so với các phương pháp nối khác (p < 0.001). Không có sự khác biệt về lượng máu mất, thời gian nằm viện, tỉ lệ chuyển mổ mở, tỉ lệ và độ nặng của các biến chứng. PHLT kiểu R-Y duy trì chỉ số albumin máu tốt hơn các phương pháp nối còn lại (p < 0.001), không khác biệt về các mặt duy trì cân nặng, duy trì nồng độ hemoglobin. Kết quả nội soi sau 1 năm không khác biệt về tỉ lệ viêm thực quản trào ngược, viêm phần còn lại của dạ dày giữa các PHLT. Kiểu B-I tồn dư thức ăn khá cao (độ 1-2: 11.7%, độ 3: 5.9%, độ 4: 2.9%). Kiểu R-Y cho tỉ lệ có dịch mật ở miệng nối ít nhất (4.8%), theo sau là B-II Braun (14.2%) và B-I, B-II-h, B-II-ds. Kết luận: PHLT kiểu Roux-en-Y có thời gian phẫu thuật dài hơn, nhưng kết quả thuận lợi về mặt dinh dưỡng và giảm trào ngược dịch mật. PHLT kiểu B-I có tỉ lệ tồn đọng thức ăn cao. PHLT kiểu B-II khâu treo quai đến đơn giản về kĩ thuật, kết quả thuận lợi về chức năng và dinh dưỡng.
Analisis kinerja keuangan sebelum dan pada saat pandemi covid-19 pada perusahaan di bursa efek indonesia
Authors: Sidabutar Herlina Yusrianti , Silaban Pasaman , Panjaitan Raya
Published: January 2024

Pandemi Covid-19 telah menyebabkan banyak perusahaan jasa pada sub-sektor pariwisata ditutup sementara. Hal tersebut berdampak pada kinerja keuangan perusahaan yang bergerak di sub-sektor ini. Penelitian ini bertujuan untuk mengetahui adanya perbedaan kinerja keuangan perusahaan pada sub-sektor jasa pariwisata sebelum dan pada saat pandemi Covid-19. Kinerja keuangan diukur dengan menggunakan beberapa rasio, yaitu rasio likuiditas, rasio solvabilitas, rasio profitabilitas dan rasio pasar. Jenis penelitian yang dilakukan adalah penelitian kuantitaitf deskriptif. Populasi dalam penelitian ini adalah 25 seluruh perusahaan sub-sektor pariwisata yang terdaftar di Bursa Efek Indonesia periode 2019-2020. Sampel dikumpulkan 20 perusahaan dengan menggunakan metode purposive sampling. Pengujian hipotesis dilakukan dengan menggunakan paired sample t-test. Hasil empiris menunjukkan bahwa, pada rasio likuiditas, rasio profitabilitas, dan rasio solvabilitas tidak terdapat perbedaan yang signifikan di antara periode sebelum dan periode pada saat terjadinya kasus Covid-19 pertama kali diumumkan di Indonesia. Sedangkan, pada rasio pasar, terdapat perbedaan yang signifikan di antara kedua periode tersebut.
Pengaruh harga, promosi, dan word of mouth terhadap minat pembelian konsumen mobil honda PT. Istana Deli Kejayaan (IDK2) Medan
Authors: Viola  , Margery Errie , Seri
Published: January 2024

Seiring berjalannya waktu dan berkembangnya zaman, kini mobil sudah menjadi salah satu benda utama yang bisa dibeli. Salah satu dealer mobil Honda yang ternama di Medan adalah PT. Istana Deli Kejayaan yang berlokasi di Jalan Sei Batang Hari No. 22-24, merupakan perusahaan yang bergerak di bidang otomotif dan telah berdiri sejak tahun 2004 hingga saat ini. Banyak faktor yang mempengaruhi minat beli konsumen, dimana aspek yang cukup penting dan spesifik adalah harga, promosi dan word of Mouth. Teori yang digunakan adalah teori manajemen pemasaran yang berkaitan dengan harga, promosi, promosi dari mulut ke mulut dan minat beli. Penelitian ini menggunakan penelitian deskriptif kuantitatif. Populasi dalam penelitian ini adalah 105 pelanggan. Metode pengumpulan data yang digunakan dalam penelitian adalah wawancara, penyebaran kuesioner dan studi dokumenter. Teknik pengambilan sampel dengan rumus Slovin diperoleh sebanyak 83 sampel. Variabel-variabel dalam penelitian ini diukur menggunakan skala likert. Secara parsial harga dan promosi berpengaruh negatif dan tidak signifikan terhadap minat beli konsumen, sedangkan word of Mouth berpengaruh positif dan signifikan terhadap minat beli konsumen. Secara simultan terdapat pengaruh yang signifikan antara Harga, Promosi dan Word of Mouth terhadap Minat Beli Konsumen pada PT. Istana Deli Kejayaan (IDK2) Medan.
Analisis Pengaruh Tingkat Kesehatan Bank Terhadap Profitabilitas Perbankan di Bursa Efek Indonesia
Authors: Silaban Frederick
Published: January 2024

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh tingkat kesehatan bank terhadap profitabilitas perbankan di Bursa Efek Indonesia. Variabel Independen (X) dalam penelitian ini adalah Tingkat Kesehatan Bank (CAR, NIM, NPL dan LDR), sedangkan variabel profitabilitas (ROA) sebagai variabel dependen dalam penelitian ini. Sifat penelitian ini dengan deskriptif eksplanatori yaitu penelitian yang bermaksud menjelaskan kedudukan variabel-variabel yang diteliti serta hubungan antara satu variabel dengan variabel lainnya. Populasi dalam penelitian ini adalah seluruh bank negeri dan swasta yang terdaftar di Bursa Efek Indonesia (BEI). Jumlah populasi perbankan pemerintah dan swasta adalah sebanyak 40 bank. Tahun pengamatan dimulai dari Tahun 2018 sampai dengan Tahun 2022. Berdasarkan kriteria pemilihan sampel diperoleh total sampel sebanyak 27 bank umum yaitu bank pemerintah dan swasta yang tercatat di Bursa Efek Indonesia pada periode penelitian tahun 2018-2022.

Teknik pengumpulan data dilakukan dengan studi dokumentasi yang dilakukan dengan cara mengakses situs resmi Bursa Efek Indonesia. Data yang digunakan merupakan gabungan data antara perusahaan (cross section) dan antar waktu (timeseries) yang disebut juga dengan polling data dan diteliti pada situs resmi www.idx.co.id serta berbagai penerbitan yang mempublikasikan data ekonomi makro indonesia. Hasil dari penelitian ini menunjukkan adanya pengaruh Capital Adequacy Ratio (CAR) dan Non Performing Loan (NPL) secara signifikan terhadap profitabilitas (ROA) pada bank-bank umum dan swasta yang terdaftar di Bursa Efek Indonesia periode 2018-2022. Sedangkan variabel Net Interest Margin (NIM) dan Loan to Deposit Ratio (LDR) tidak berpengaruh signifikan terhadap profitabilitas (ROA) pada bank-bank umum dan swasta yang terdaftar di Bursa Efek Indonesia periode 2018-2022. Secara simultan variabel Capital Adequacy Ratio (CAR), Non Performing Loan (NPL), Net Interest Margin (NIM) dan Loan to Deposit Ratio (LDR) berpengaruh secara signifikan terhadap profitabilitas (ROA) pada bank-bank umum dan swasta yang terdaftar di Bursa Efek Indonesia periode 2018-2022.
Productivity of the Great Egret (Ardea alba) and Grey Heron (A. cinerea) in mixed heronries in Poland and behavioral response of fledglings to a drone
Authors: Zbyryt Adam , Mitrus Cezary , Neubauer Grzegorz
Published: January 2024

Productivity of avian populations provides important demographic information helpful in understanding population dynamics and processes involved during species expansions. We tested the hypothesis that the productivity of the two species of ecologically similar herons that breed together in mixed heronries is related to their expansion status. We expected the expansive species, colonizing the new area and increasing in numbers, to outperform the native species, whose abundance is stable. We studied the breeding success of two herons in mixed colonies in eastern Poland in 2018: Great Egret (Ardea alba) (an expansive species, increasing breeding range and population size), and the Grey Heron (Ardea cinerea) (a native species, stable breeding population). Mean productivity (number of young per nest) was similar for Great Egret and Grey Heron and appeared correlated to each other in mixed heronries. Productivity of both species was unrelated to the colony size, but Grey Heron tended to have higher productivity as the proportion of Great Egret nests in the colony increased. Similar productivity of both species can be explained by the sufficient food resources coupled with the low level of competition. The two species differed significantly in their response of young to the approaching drone: the mean probability of a young Great Egret adopting an upright display was 0.47 compared to only 0.18 in a young Grey Heron (P=0.025). This was unlikely an age-related difference as the fledglings of both species were at a similar stage of development, but may represent some kind of a species-specific trait. Our research once again shows that UAVs allow a quick and non-invasive study of the size of the breeding populations and reproductive performance of herons, egrets and other wading birds.
2023 Belgian consensus on Helicobacter pylori treatment, yet another (Belgian) guideline
Authors: Rasschaert G , Ntounda R
Published: January 2024

The Belgian Helicobacter and Microbiota Study Group (BHMSG) welcomes the publication of their new Belgian consensus on the treatment of Helicobacter pylori (Hp) in the Acta Gastro-Enterologica Belgica. Vol 86, January-March (74-91), 2023 (1). We carried out a survey through a questionnaire on the treatment habits of Belgian practitioners at the end of 2020. This 30 questions survey was distributed through the Belgian professional associations of gastroenterology and general practitioners. 138 responses were received in total, including 95 Belgian and 43 African physicians.
Carbon cycle feedbacks in an idealized simulation and a scenario simulation of negative emissions in CMIP6 Earth system models
Authors: Asaadi Ali , Schwinger Jörg , Lee Hanna , Tjiputra Jerry , Arora Vivek , Séférian Roland , Liddicoat Spencer , Hajima Tomohiro , Santana-Falcón Yeray , Jones Chris D.
Published: January 2024

Abstract. Limiting global warming to well below 2 ∘C by the end of the century is an ambitious target that requires immediate and unprecedented emission reductions. In the absence of sufficient near-term mitigation, this target will only be achieved by carbon dioxide removal (CDR) from the atmosphere later during this century, which would entail a period of temperature overshoot. Aside from the socio-economic feasibility of large-scale CDR, which remains unclear, the effects on biogeochemical cycles and climate are key to assessing CDR as a mitigation option. Changes in atmospheric CO2 concentration and climate alter the CO2 exchange between the atmosphere and the underlying carbon reservoirs of the land and the ocean. Here, we investigate carbon cycle feedbacks under idealized and more realistic overshoot scenarios in an ensemble of Earth system models. The responses of oceanic and terrestrial carbon stocks to changes in atmospheric CO2 concentration and changes in surface climate (the carbon–concentration feedback and the carbon–climate feedback, quantified by the feedback metrics β and γ, respectively) show a large hysteresis. This hysteresis leads to growing absolute values of β and γ during phases of negative emissions. We find that this growth over time occurs such that the spatial patterns of feedbacks do not change significantly for individual models. We confirm that the β and γ feedback metrics are a relatively robust tool to characterize inter-model differences in feedback strength since the relative feedback strength remains largely stable between phases of positive and negative emissions and between different simulations, although exceptions exist. When the emissions become negative, we find that the model uncertainty (model disagreement) in β and γ increases more strongly than expected from the assumption that the uncertainties would accumulate linearly with time. This indicates that the model response to a change from increasing to decreasing forcing introduces an additional layer of uncertainty, at least in idealized simulations with a strong signal. We also briefly discuss the existing alternative definition of feedback metrics based on instantaneous carbon fluxes instead of carbon stocks and provide recommendations for the way forward and future model intercomparison projects.
Measurement report: Contribution of atmospheric new particle formation to ultrafine particle concentration, cloud condensation nuclei and radiative forcing: Results from five-year observations in Central Europe
Authors: Sun Jia , Hermann Markus , Weinhold Kay , Merkel Maik , Birmili Wolfram , Yang Yifan , Tuch Thomas , Flentje Harald , Briel Björn , Ries Ludwig , Couret Cedric , Elsasser Michael , Sohmer Ralf , Wirtz Klaus , Meinhardt Frank , Schütze Maik , Bath Olaf , Hellack Bryan , Kerminen Veli-Matti , Kulmala Markku , Ma Nan , Wiedensohler Alfred
Published: January 2024

Abstract. As an important source of sub-micrometer particles, atmospheric new particle formation (NPF) has been observed in various environments. However, most studies provide little more than snapshots of the NPF process due to their underlying observations being limited in space and time. To obtain statistically relevant evidence on NPF across various environments, we investigated the characteristics of NPF based on a five-year dataset of the German Ultrafine Aerosol Network (GUAN). The results were also compared with the observations in previous studies, aiming to depict a relatively complete picture of NPF in Central Europe. The highest NPF frequency was observed in regional background, with an average of about 20 %, followed by urban background (15 %), low mountain range (8 %) and high Alpine (3 %). The annual mean growth rate varied from 3.67 to 4.70 nm h−1, while the formation rate from 0.43 to 2.89 cm−3 s−1. The contribution of NPF on UFPs was about 13 %, 21 %, and 7 % for the urban background, regional background, and low mountain range, respectively. The influence of NPF on CCN number concentration and aerosol extinction coefficient for NPF days were the highest in mountainous area. These findings underscore the importance of the local environments when assessing the potential impact of NPF on regional climate in models, and also emphasize the usefulness of a long-term aerosol measurement network for understanding the variation of NPF features and their influencing factors over a regional scale.
An improved global pressure and ZWD model with optimized vertical correction considering the spatial-temporal variability of multiple height scale factors
Authors: Jiang Chunhua , Gao Xiang , Zhu Huizhong , Wang Shuaimin , Liu Sixuan , Chen Shaoni , Liu Guangsheng
Published: January 2024

Abstract. Atmospheric pressure and Zenith wet delay (ZWD) are essential for GNSS tropospheric correction and precipitable water vapor (PWV) retrieval. As the development progresses of real-time GNSS kinematic technology, moving platforms such as airborne and shipborne require high-quality tropospheric delay information to pre-correct errors. Most existing tropospheric models are only applicable to the Earth surface, while exhibiting poor accuracies in high-altitude areas due to simple vertical fitting functions and limited temporal resolution of the underlying parameters. Hence, an improved global empirical pressure and ZWD model is developed using 5-years ERA5 hourly reanalysis data, called IGPZWD, which takes seasonal and intraday variations into consideration. The vertical accuracy and applicability of IGPZWD model are further optimized by introducing the annual and semi-annual harmonics for pressure and ZWD height scale factors of exponential function with three orders. Taking the ERA5 and radiosonde profiles data in 2020 as reference, the pressure and ZWD of IGPZWD model show superior performance than those of three state-of-the-art models, i.e., GPT3, IGPT and GTrop. Furthermore, IGPZWD-predicted ZTD yields improvements of up to 65.7 %, 2.4 % and 7.8 % over that of GPT3, RGPT3 and GTrop models on a global scale respectively. The proposed vertical correction algorithm effectively weakens the impact of accumulation error caused by excessive height difference, achieving optimal accuracy and feasibility in the high-altitude area. The IGPZWD model can be extensively applied in GNSS kinematic precision positioning as well as atmospheric water vapor sounding.
Combining a ground-based UV network with satellite maps: A case study for Germany
Authors: Klotz Barbara , Schenzinger Verena , Schwarzmann Michael , Kreuter Axel
Published: January 2024

Abstract. A study for the comprehensive information of current UV exposure for the area of Germany, based on the method for near real time calculation of UV Index maps used in the framework of the Austrian UV Monitoring Network, is presented. For the area of Germany about 22.000 surface UV Index maps were calculated for the year 2022 via the radiative transfer model libRadtran by incorporating daily forecast data for ozone, albedo and aerosols from the Copernicus Atmospheric Monitoring Service and taking into account cloud information gathered from SEVIRI data of Meteosat Second Generation in the form of a cloud modification factor. Ground-based measurements of 17 stations of the German Solar Monitoring Network were then compared to the modelled maps. For most stations the correlation coefficient between measured and modelled UV Index (UVI) is above 0.92 and the mean difference of modelled UVI to measured UVI is smaller than 0.5 UVI. The modelling of the UVI at the high mountain station Schneefernerhaus is associated with higher uncertainties (correlation coefficient 0.85 and mean UVI difference 0.6 UVI) due to the small-scale topography with spatially highly variable albedo and clouds. Moreover, case studies for specific locations with respect to cloud conditions and topography are discussed, as well as a case study of the combination of ground-based measurements and modelled UVI maps in form of spatial correction factors.
Observation and simulation of neutral air density in the middle atmosphere during the 2021 sudden stratospheric warming event
Authors: Yang Junfeng , Wang Jianmei , Liu Dan , Guo Wenjie , Zhang Yiming
Published: January 2024

Abstract. Sudden stratospheric warmings (SSWs) are dramatic events in the polar winter stratosphere that are accompanied by atmospheric parameter anomalies in the stratosphere and mesosphere. Microwave Limb Sounder and Global Navigation Satellite System Occultation Sounder observations on board the Chinese FengYun 3 satellites indicate a rapid increase of over 50 % in the mesospheric density at high latitudes around the onset date during the 2021 major SSW event. The amplification of the zonal mean density around the onset is proportional to the latitude increase with a maximum increment of 83.3 % at 59 km above 80° N, which is more than three times larger than the climatological standard deviation (23.1 %). The horizontal density distributions are influenced by the changing polar vortex fields. A simulation using a specified dynamics version of the Whole Atmosphere Community Climate Model is consistent overall with the observations and presents a severe change in the planetary wave forcing and residual meridional circulation mass flux followed by a change in the density tendency. These results demonstrate that the observed enhanced density is primarily attributed to the altered planetary waves and residual circulation during the SSW event. The observations and simulations also indicate that the density anomalies could extend to middle latitudes. Obvious density disturbances in the upper stratosphere and mesosphere were observed by lidar deployed in Beijing (40.3° N, 116.2° E).
Air mass history linked to the development of Arctic mixed-phase clouds
Authors: Murray-Watson Rebecca J. , Gryspeerdt Edward
Published: January 2024

Abstract. Clouds formed during marine cold-air outbreaks (MCAOs) exhibit a distinct transition from stratocumulus decks near the ice edge to broken cumuliform fields further downwind. The mechanisms associated with ice formation are believed to be crucial in driving this transition, yet the factors influencing such formation remain unclear. Through Lagrangian trajectories co-located with satellite data, this study investigates into the development of mixed-phase clouds using these outbreaks. Cloud formed in MCAOs are characterized by a swift shift from liquid to ice-containing states, contrasting with non-MCAO clouds also moving off the ice edge. These mixed-phase clouds are predominantly observed at temperatures below -20 °C near the ice edge. However, further into the outbreak, they become the dominant at temperatures as high as -13 °C. This shift is consistent with the influence of biological ice nucleating particles (INPs), which become more prevalent as the air mass ages over the ocean. The evolution of these clouds is closely linked to the history of the air mass, especially the length of time it spends over snow- and ice-covered surfaces, terrains may that be deficient in INPs. This connection also accounts for the observed seasonal variations in the development of Arctic clouds, both within and outside of MCAO events. The findings highlight the importance of understanding both local marine aerosol sources near the ice edge and the overarching INP distribution in the Arctic for modelling of cloud phase in the region.