bluuebunny/crossref_metadata_2025 huggingface dataset:
Competency-Based Assessment in Entrepreneurship Education in Kenya’s Tertiary Institutions
Authors: Moindi Rose , Nyatuka Benard
Published: July 2022

Education systems worldwide are shifting to knowledge-based curricula with emphasis on the learners’ acquisition of relevant competencies. Entrepreneurship education was introduced in tertiary institutions in Kenya in 1999 to produce entrepreneurs, including preparing graduates for the world of work. However, limited studies have focused on the assessment of acquisition of such competencies, especially in entrepreneurship education.  This study was designed to examine the effectiveness of assessment modes used in entrepreneurship education in imparting requisite competencies among students in tertiary institutions in the country. The study adopted a cross-sectional research design. A total of 412 students selected from three tertiary institutions were involved in the study. Data were collected using questionnaires and analysed quantitatively using descriptive and inferential statistics. The study showed that written examinations were the most commonly used mode of assessment of entrepreneurship education, followed by projects and attachment. The study revealed that there is no significant difference in the influence of the mode of assessment as adopted in the different tertiary institutions in fostering the acquisition of competencies (F Ratio<F Critical) (0.835<3.02). However, when the requisite competencies were compared, the study showed that the mode of assessment adopted enhanced acquisition of ideas and opportunities (0.313 units) and resources (0.364 units) competencies more compared to the into-action competencies (0.249 units). To enhance the acquisition of relevant competencies, the study recommends adoption of different appropriate modes of assessment in entrepreneurship education.
Gender differences in adolescents with suicidal behaviour: Personality and psychopathology
Authors: Villar-Cabeza F. , Lombardini F. , Sánchez-Fernández B. , Vila-Grifoll M. , Esnaola-Letemendia E. , Vergé-Muñoz M. , Navarro-Marfisis M. C , Castellano-Tejedor C.
Published: July 2022

This study evaluates the relationship between gender, personality, psychopathology and suicidal behaviour among adolescents. For this purpose, across-sectional study with adolescent inpatients (N = 92) displaying suicidal behaviour was designed. Sociodemographic characteristics and data related to suicidal behaviour were collected. In addition, personality and clinical severity were assessed by administering the Millon Adolescent Clinical Inventory (MACI). Results revealed that the most prevalent personality dimensions for both genders were Introversive, Self-demeaning, Doleful, Oppositional, Borderline tendency and Inhibited. However, men scored higher in Inhibited (p = 0.02, Cohen’s d = 0.45) and women in Egotistic(p = 0.03, Cohen’s d = 0.40). Concerning clinical severity of syndromes, women scored higher in Delinquent Predisposition (p = 0.04, Cohen’s d = 0.45) and men in Anxious Feelings (p = 0.02, Cohen’s d = 0.51), Depressive Affect (p = 0.04, Cohen’s d = 0.41) and Suicidal Tendency (p = 0.03, Cohen’s d = 0.37), with men reporting more frequently Childhood Abuse (p < 0.001, Cohen’s d= 0.70). Results highlight the importance of universal interventions to promote a change in attitudes towards seeking psychological help, specially in men, and the need to design effective tailored treatments to acquire emotional management skills for both genders
The peculiarities of Adaptation of First-Year Students to the University during COVID-19 Pandemic in Russia
Authors: Nugmanova Dzhamilia , Kozlova Inna , Kupriyanov Roman
Published: July 2022

The speed and efficiency of student adaptation largely determines the success of the educational process. This is especially true for university freshmen, as the older adolescent organism, with its specific neurophysiological characteristics, is very sensitive to changes in the environment. The situation with SARS-CoV-2 virus (COVID-19) pandemic has added to the problem of adaptation. The present study aims to examine the influence of the COVID-19 pandemic on the first-year students’ adaptation to university studies in Russia. The study involves 692 freshmen with an average age of 18.7, majority of women (80.6%), from three Russian universities: Kazan National Research Technological University, Kazan Federal University and Kazan Aviation University. The results show that during the COVID-19 period statistically significant changes occurred in almost all the adaptation components: physiological adaptation (p < .0001), socio-psychological adaptation (p < .05), academic adaptation (p < .05). There was a decrease in the level of physiological adaptation, while socio-psychological adaptation and academic adaptation increased. Comparison by gender during the COVID-19 period shows differences between adaptation processes of men and women. Comparison of foreign students with Russian citizens during the COVID-19 period demonstrates that foreign students stand out in socio-cultural adaptation (4.94 - foreigners, 4.64 - citizens of Russia, p < .05), physiological adaptation (5.36 - foreigners, 4.36 - citizens of Russia, p < .00001) and academic adaptation (5.28 - foreigners, 4.99 - citizens of Russia, p < .05)
Kesulitan Pemilihan Diksi dan Strategi dalam Penerjemahan
Authors: Apriyanti Chusna , Shinta Uly Karta Diayu
Published: July 2022

Penelitian ini bertujuan untuk mengetahui kesulitan mahasiswa dalam pemilihan diksi penerjemahan dan menjelaskan strategi untuk mengurangi kesulitan pemilihan diksi dan meningkatkan kualitas hasil terjemahan untuk mahasiswa. Penelitian ini menggunakan desain penelitian deskriptif kualitatif. Data diperoleh dengan angket melalui platform Google Form terhadap 20 mahasiswa Program Studi Pendidikan Bahasa Inggris STKIP PGRI Pacitan yang telah menempuh mata kuliah Translation 1 dan 2. Selain menggunakan angket, peneliti juga melakukan wawancara terhadap subjek penelitian. Penelitian dilakukan selama bulan Mei 2021. Setelah data dikumpulkan, peneliti menyajikan data penelitian, membuat bahasan hasil data penelitian, dan menarik kesimpulan. Hasil penelitian menyebutkan bahwa seluruh responden mengaku memiliki kesulitan primer dalam pemilihan kata/diksi ketika menerjemahkan teks. Kesulitan tersebut disebabkan oleh kurangnya perbendahaan kosakata, teks yang mengandung istilah budaya, serta jenis teks tertentu seperti puisi. Lemahnya pengetahuan yang menyebabkan information gap juga menjadi problem dalam penerjemahan. hal tersebut menyebabkan kesulitan dalam memilih kata. Beberapa strategi yang bisa diimplementasikan oleh mahasiswa untuk mengurangi kesulitan pemilihan diksi dan meningkatkan kualitas hasil terjemahan adalah sebagai berikut: meningkatkan perbendaharaan kosakata dengan membaca, menggunakan kamus rumpun ilmu, menggunakan mesin terjemahan hanya sebagai alat bantu, membaca teks berulang kali setelah diterjemahkan.
Implementasi Model Pembelajaran Think Paire Share Berbantuan Video Pembelajaran untuk Meningkatkan Motivasi Belajar Siswa Kelas IV SD No. 6 Darmasaba
Authors: Mahendra Kadek Gede
Published: July 2022

Penelitian ini bertujuan untuk meningkatkan motivasi belajar siswa melalui implementasi model pembelajaran think paire share berbantuan video pembelajaran untuk meningkatkan motivasi belajar siswa kelas IV SD No. 6 Darmasaba. Jenis penelitian ini merupakan penelitian tindakan kelas. Secara ringkas, penelitian ini dilaksanakan dalam dua siklus, yang meliputi empat tahapan yaitu: perencanaan, pelaksanaan, observasi, dan refleksi. Sampel penelitian ini adalah siswa kelas IV SD No. 6 Darmasaba yang berjumlah 22 siwa, terdiri dari 15 siswa laki-laki dan 7 siswi perempuan. Lokasi penelitian dilaksanakan di SD No. 6 Darmasaba. Data analisis motivasi belajar siswa diperoleh melalui lembar observasi. Adapun hasil penelitian yang diperoleh pada siklus I sebesar 68,33% dan meningkat 15% pada siklus II menjadi 83,33%. Berdasarkan hasil penelitian tersebut dapat disimpulkan bahwa implementasi model pembelajaran think paire share berbantuan video pembelajaran dapat meningkatkan motivasi belajar siswa kelas IV SD No. 6 Darmasaba.
Respuesta al aumento de visitantes en los Espacios Naturales Protegidos de Cataluña en tiempos de COVID-19: una revisión a partir de publicaciones en medios de comunicación digitales
Authors: Medina-Chavarría María E. , Gutiérrez Aaron , Saladié Òscar
Published: July 2022

El artículo analiza la respuesta de los gestores de los espacios naturales protegidos de Cataluña al extraordinario aumento de visitantes acaecido durante el periodo post-confinamiento y de relajación de las restricciones de movilidad implementadas en respuesta a la pandemia de la COVID-19, según lo informado a la ciudadanía a través de los medios de comunicación digital. Para ello se ha realizado una revisión sistemática de 105 noticias publicadas entre mayo y diciembre del 2020. Los resultados sugieren que en los espacios naturales protegidos se implementaron preferentemente acciones enfocadas en responder a la inmediatez de la situación; es decir, soluciones a corto plazo vinculadas a la gestión del aforo y de los accesos. Las acciones de información y educación ambiental fueron más tardías y las acciones de gestión de flujos dentro de los espacios naturales protegidos fueron escasamente reportadas por los medios consultados. Nuestro estudio es un primer paso para dimensionar y caracterizar las estrategias implementadas por los organismos gestores de los espacios naturales protegidos para hacer frente a la avalancha de visitantes. Además, contribuye a reducir la brecha existente en el estudio de las implicaciones de la COVID-19 en la gestión de los espacios naturales protegidos.
Cuatro dilemas y un obstáculo a la gobernanza metropolitana: respuestas desde la planificación estratégica urbana
Authors: Gañán Sánchez Elena , Merinero Rodríguez Rafael , Huete García María Ángeles
Published: July 2022

¿Qué tipo de gobernanza se debe promover para las áreas metropolitanas en el siglo XXI? Esta pregunta, que parece actual, es la misma que se lleva haciendo desde hace tiempo en la literatura científica, así como en las instituciones y organizaciones implicadas en las políticas urbanas. Su respuesta ha ido variando a lo largo de los años, si bien recurrentemente ha procedido del ámbito institucional. Este trabajo tiene como propósito reflexionar sobre las posibles respuestas a los dilemas de la gobernanza metropolitana desde el punto de vista de las políticas públicas, concretamente, los planes estratégicos urbanos. Dichos instrumentos, planteados en coherencia con el Modelo de Desarrollo Urbano Sostenible Integrado (MDUSI), se muestran como un instrumento de política pública eficaz para dar respuesta a los retos que enfrentan las áreas metropolitanas en la actualidad.
Una aproximación a los efectos sociales de la agricultura de regadío
Authors: Ortiz Guadalupe , Aledo Antonio , Aznar-Crespo Pablo , Mañas-Navarro José Javier
Published: July 2022

La expansión de la agricultura de regadío en el sureste español ha generado un intenso debate en torno a la dicotomía economía vs. medio ambiente del que han quedado tradicionalmente excluidos los criterios sociales. Para afrontar esta carencia, el objetivo de este estudio ha consistido en identificar y visibilizar los principales efectos sociales de la agricultura de regadío, mediante el caso de estudio del área de actuación de la Comunidad de Regantes del Campo de Cartagena. La metodología ha empleado cinco fuentes de datos: revisión bibliográfica, análisis de hemeroteca, análisis de datos secundarios, entrevistas semiestructuradas con actores clave y entrevistas estructuradas con empresas agrícolas. Los resultados se dividen en tres subapartados: a) demografía, que muestra las transformaciones poblacionales asociadas al desarrollo de la agricultura de regadío; b) empleo y distribución de la riqueza, que señala el papel del sector como motor de generación de empleo, y la persistencia de condiciones laborales precarias; c) responsabilidad y legitimidad social, que aborda la crisis de reputación del sector y las medidas de responsabilidad empresarial aplicadas para contrarrestarla. Así, el estudio trasciende el tradicional debate dicotómico, discutiendo la incidencia social del sector del regadío e identificando áreas de responsabilidad para una gestión socialmente sostenible.
Technology Focus: Cementing and Zonal Isolation (May 2022)
Authors: James Simon
Published: July 2022

Over the past year, the number of cementing and zonal-isolation papers was much lower than usual because of the cancellation and postponement of several conferences. The overall impact, however, was mitigated by the transformation of several conferences to online events. I attended one virtual event and was pleasantly surprised with the value of the technical discussions that immediately followed each paper presentation and the willingness of authors to follow up on discussions after the conference.

The development of new technology can take a significant amount of time and resources, and full worldwide introduction may take many years, giving rise to a commercial risk for the technology developer. One paper published last year described the first case history of self-healing cement technology in one geographical area more than 10 years after the publication of the first field application of the technology.

In the October 2021 issue of JPT, SPE President Kamel Ben-Naceur discussed the importance of collaboration in solving technical problems quickly and efficiently. Three of the papers selected in this section are from collaborations between multiple companies pooling their expertise and resources to develop solutions for complex problems that could not be addressed efficiently by individual companies. Papers SPE 204015 and SPE 208782 issue from consortia whose goals are to improve the efficiency and reliability of plugging-and-abandonment operations. Paper SPE 204103 is a jointly funded collaboration evaluating CO2-resistant cement with a new experimental methodology to accelerate chemical interactions between the cement and CO2, thus shortening the validation time.

The commercial risks associated with the incremental developments of existing technology can be acceptable more readily to individual companies, although this does not mean that efficient internal teamwork is not required. The three other papers selected are all supported and authored by individual companies, but each is a collaboration between multiple people with different expertise—experimental and poromechanical modeling expertise in paper

SPE 206144, chemical synthesis and microfluidics expertise in paper SPE 207472, and cement chemistry and experimental expertise in paper SPE 208679.

Recommended additional reading at OnePetro: www.onepetro.org.

SPE 204103 Evaluation of New Innovative Cement Blend for Enhanced CO2 and H2S Resistance by Gunnar Lende, Halliburton, et al.

SPE 206144 Advanced Cement Mechanical Integrity for Thermal Wells by Manh-Huyen Vu, Curistec, et al.

SPE 207472 Associative Microgels, New Self-Adaptive Systems To Control Fluid Loss in Well Cementing by Arnaud Cadix, Solvay, et al.
Metaverse skiing system linked with real-time environmental elements of the ski resort
Authors: Li Tan , Wang Hong , Yue Zaituo , Lan Qin , Fan Dongchuan , Li Ziyang , Zhang Bo , Yan Shiyu
Published: July 2022

This paper presents a virtual ski training system based on changes in environmental elements of ski resort. The aim of the system is to allow skiers to ski training without going to a ski resort, increase tactical training in the face of different environments and help skiers improve their performance. The system uses VR technology to construct a realistic ski training scenario. 5G cloud platform transmissions are connected to the actual ski resorts to obtain real-time environmental elements data to import into the VR system in order to construct a dynamic model of the environment. The effectiveness of the system was verified through a combination of indoor and outdoor tests to analyse participants' skiing speed in both real and virtual scenarios. In conjunction with questionnaires completed by the participants, differences in the effectiveness of the participants' experience of the different dimensions of the system were analysed. The results show that this VR system is effective in simulating actual ski resorts and is an effective aid for skiers, especially less experienced ski students.
Locked posterior Shoulder Dislocation with impression Fracture treated all arthroscopically with the use of an Allograft Bone Block A Case Report
Authors: Blasiak Adrian , Podsiadlo Mikolaj , Śliwa Marek , Brzoska Roman
Published: July 2022

Locked posterior shoulder dislocations are uncommon and poses many difficulties in diagnosis. They are often overlooked during initial exam- ination and delayed diagnosis adversely affects healing process. Apart from many open treatment options there are reports of single attempts to treat such cases arthroscopically. We present an original case of a posterior locked dislocation of the shoulder joint with a fracture of the lesser tuberosity followed by reverse Hill-Sachs fracture, treated in a novel fashion all-arthroscopically with the use of allogenic bone graft. According to Constant Shoulder Score that tries to asses functional and subjective performance of the shoulder joint before the operation and after 12 months, we achieved a leap from 11% to 84%. The patient restored almost full range of motion and painless movement in activ- ities of daily life as well as during sports. The use of an arthroscope reduces the invasiveness of the procedure, improves visualization of the joint and allows augmentation of the bone loss without perform- ing an open approach. We believe that this is A promising method of treatment for selected cases of locked posterior shoulder dislocation.
High-sensitivity C-reactive Protein is a Predictor of Depression in Patients with Mild Traumatic Brain Injury
Authors: Eujene Jung , Ryu Hyun Ho
Published: July 2022

IntroductionDepression is one of the most common psychological problems after mild traumatic brain injury (mTBI) and affects various aspects of life quality. Previous studies demonstrated that systematic inflammation might lead to unfavorable outcomes, including depression after TBI. Therefore, we analyzed the relationship between the serum level of high sensitive C-reactive protein (hsCRP), a sensitive biomarker of systematic inflammation, and depression incidence after mTBI.MethodsWe used data from Korea’s Level-1 trauma center registry between Jan 2018 to Dec 2019. The population of our study was adult mTBI patients who visited the Level-1 trauma center using emergency medical service (EMS). We used the serum level of hsCRP measured just after arrival at the emergency department as the primary data input. The main outcome was depression evaluated 6 months after hospital discharge using the Beck depression inventory. Multivariable logistic regression analyses were performed to estimate the effect of hsCRP level on depression incidence. In addition, interaction analyses of the association between hsCRP and fever on depression incidence were performed.ResultsA total of 257 mTBI patients were enrolled. The multivariable logistic regression analysis showed that an elevated serum level of hsCRP was associated with higher odds of depression (aOR (95% CI): 1.34 (1.03—1.69)). The association was maintained only in the fever group (1.42 (1.14—1.78)).ConclusionsElevated serum level of hsCRP was associated with an increased incidence of depression 6 months after hospital discharge. This effect was maintained in the presence of fever. Our study results suggest the need for adopting strategies to prevent depression when systematic inflammation is indicated by CRP elevation and/or fever in mTBI patients.
Gender Differences in Obstructive Sleep Apnea with Comorbid Treatment-Resistant Depression
Authors: Kasurak Emily , Hawken Emily , Kolar Dusan , Jokic Ruzica
Published: July 2022

Background. A bidirectional relationship between major depression and obstructive sleep apnea has been established, suggesting the possibility of overlapping and compounding disease processes. Depression, however, while more prevalent in women, is a highly heterogeneous disorder and can be difficult to treat regardless of gender. A common overlapping symptom of depression and obstructive sleep apnea is fatigue. Gender differences in obstructive sleep apnea symptomatology (and fatigue in particular) are also consistently observed. Here, we investigate obstructive sleep apnea in specific relation to treatment-resistant depression. Methods. A cross-sectional design was used to analyse data from 94 patients with treatment-resistant depression from a subspecialist mood disorders outpatient service who had no previous sleep assessment. Participants completed overnight polysomnography and a battery of rating scales assessing mood, sleep, and daytime functioning. Linear regression models determined whether presence of fatigue in treatment-resistant depression predicted sleep obstructive apnea severity. Results. There was a high prevalence of previously undiagnosed obstructive sleep apnea in our sample of patients with treatment-resistant depression. Treatment-resistant depression closed the gap in obstructive sleep apnea prevalence between men and women. Conclusions. We argue that typical symptoms of treatment-resistant depression may overshadow key symptoms of undetected obstructive sleep apnea. Specifically, we found that daytime fatigue masked a potentially significant underlying sleep disorder in women only. Comprehensive assessment and screening for sleep apnea in patients with treatment-resistant is encouraged, and the importance of investigating severity of fatigue in this population is emphasized.
Fine mapping a single nucleotide transversion in AUXIN RESPONSE FACTOR 18 controls prickle absence/presence on various organs in eggplant (Solanum melongena L.)
Authors: Li Shaohang , He Yongjun , Li Dalu , Shi Suli , Wang Yingying , Tang Xin , Liu Yang , Ge Haiyan , Chen Huoying
Published: July 2022

Eggplant is an important fruit vegetable from the Solanaceae family, with rich nutrition and palatability. Prickles covering plant and fruit calyxes of eggplant are considered undesirable agronomic traits, for they bring trouble and create additional costs for farmers. Prickle is a sharp protrusion that is common in plants, but little is known about its regulatory genes and molecular mechanism of morphogenesis. In this study, two eggplant inbred lines, prickly ‘140’ and prickleless ‘145’ were applied to construct F1 , BC1 , and F2 offspring populations. Genetic analysis results showed that prickle’s absence/presence on various organs in eggplant was controlled by only one dominant nuclear gene. The PRICKLE LOCUS ( Pl ) was fine mapped into a candidate interval with 28.3 Kb on chromosome 6 ultimately by adopting bulked segregant analysis combined with genome walking strategy. An auxin response factor SmARF18 ( Smechr0602826.1 ) was deduced to be a reliable candidate gene encoded by Pl , with a non-synonymous SNP (single nucleotide polymorphism) occurring at the 1633rd nucleotide within the second exon, which encoded the middle region of the protein. The finding here could provide a basis to reveal the molecular regulatory mechanism of prickle morphogenesis in plants and breed prickle-free eggplant cultivars.
Evaluating common medications utilized in aneurysmal subarachnoid hemorrhage and association with delayed cerebral ischemia
Authors: Sorrentino Zachary A. , Desai Ansh , Eisinger Robert S. , Maciel Carolina B. , Busl Katharina M. , Lucke-Wold Brandon
Published: July 2022

Background
Spontaneous aneurysmal subarachnoid hemorrhage (aSAH) recovery may be hampered by delayed cerebral ischemia (DCI). Herein, we sought to identify an association of DCI with frequently administered medications in the neurointensive care unit (neuro-ICU).
Methods
In this retrospective study, patients admitted to a tertiary care center neuro-ICU between 2012–2019 with aSAH who could verbalize pain intensity scores were included. Medication dosages and clinical characteristics were abstracted from the medical record. Both paired (within subjects) and unpaired (across subjects) non-parametric analyses were utilized to measure individual DCI risk for a given patient in relation to drug dosages.
Results
119 patients were included; average age was 61.7 ± 15.2 (SD) years, 89 (74.7%) were female, and 32 (26.9%) experienced DCI during admission. Patients with DCI had longer length of stay (19.3 ± 7.4 vs 12.7 ± 5.3 days, p < 0.0001). The combination medication of acetaminophen 325 mg/butalbital 50 mg/caffeine 40 mg (A/B/C; Fioricet®) was associated with decreased DCI on paired (2.3 ± 2.0 vs 3.1 ± 1.9 tabs, p = 0.034) and unpaired analysis (1.84 ± 2.4 vs 2.6 ± 2.4 tabs, p < 0.001). No associations were found between DCI and opioids, dexamethasone, levetiracetam, or acetaminophen. Max and mean daily headache pain was not associated with DCI occurrence.
Conclusion
We identified a dose-response relationship between a commonly administered analgesic and DCI. A/B/C is associated with decreased DCI in this study both within and across subjects, while other medications are not associated with DCI.
Isolation and characterization of a soybean transcription factor, GmDof4.2, improves transgenic tobacco drought tolerance
Authors: Zhai Ying , Chen Jiongxin , He Jiaqi , Zhang Jun , Sha Wei , Yu Haiwei , Zhao Yan , Ma Tianyi , Sun Tianguo , Zhang Meijuan , Li Shanshan
Published: July 2022

DNA binding with one finger (Dof) is a plant-specific transcription factor (TF) that has a key role in seed development and germination, light-mediated control, and plant responses to biotic and abiotic stressors. Herein, we aimed to evaluate the role of the soybean Dof -TFs in plant resistance genetic engineering breeding. In this study, GmDof4.2 was isolated from the soybean. GmDof4.2 in soybean seedlings responded to drought, salt, heat, and cold stressors, according to the results of real-time fluorescence quantitative PCR (qPCR). GmDof4.2 protein had a 59-amino-acid Dof domain with a CX2CX21CX2C motif and four conserved cysteine (Cys) residues, according to the predicted amino acid sequence. The GmDof4.2 protein shared the most genetic similarities with the Cajanus cajan CcDof4 protein. Seven cis-elements associated with stress or hormone induction, as well as two TF binding sites, were found in the GmDof4.2 promoter region. GmDof4.2 protein bound specifically to the AAAG motif in vivo according to the results of yeast one-hybrid. Moreover, the overexpression of GmDof4.2 resulted in higher soluble carbohydrates content and proline content and lower relative electrolyte leakage and malondialdehyde content in transgenic tobacco than in wild-type (WT) tobacco under drought stress. Furthermore, the expression levels of nine stress-related genes were considerably greater in transgenic tobacco than in WT tobacco. The underlined data suggested that the GmDof4.2 improved drought tolerance in transgenic tobacco.
Hypoperfusion of amygdala in chronic migraine: an exploratory quantitative perfusion imaging using 3D pseudo-continuous arterial spin labeling
Authors: Li Xin , Liu Mengqi , Chen Zhiye
Published: July 2022

Background
Amygdala, an essential element of the limbic system, has served as an important structure in pain modulation. Although previous studies have described the structural and functional abnormalities of amygdala in chronic migraine (CM), less is known about the altered perfusion. The study aimed to measure amygdala perfusion in CM with a contrast agent-free and quantitative approach.
Methods
Thirteen CM patients and 15 normal controls were enrolled in the examination, and were performed with conventional brain structural imaging sequences and 3D pseudo-continuous arterial spin labeling (3D-PCASL). The amygdala was used as a seed region to extract volume and cerebral blood flow (CBF) value of all subjects. The correlation analysis and receiver operating characteristic curve (ROC) were used to observe the perfusion changes and explore underlying mechanism of neurolimbic pain-modulation in CM.
Results
Decreased cerebral perfusion of bilateral amygdala was identified in CM (left amygdala, 42.21 ± 4.49 ml/100mg/min; right amygdala, 42.38 ± 4.41 ml/100mg/min) compared with NC (left amygdala, 48.31 ± 6.92 ml/100mg/min; right amygdala, 47.88 ± 6.53 ml/100mg/min). There was no any significant correlation between the perfusion of bilateral amygdala and the clinical variables. And there was no significant difference for the bilateral amygdala volume between two groups. The area under curve (AUC) for the CBF value of left and right amygdala were 0.78 (95%CI 0.58–0.91) and 0.75 (95%CI 0.55–0.89), respectively. The cut-off value was 44.24 ml/100mg/min (left amygdala, with sensitivity 76.90% and specificity 78.70%) and 46.75 ml/100mg/min (right amygdala, with sensitivity 92.3% and specificity 58.80%).
Conclusion
CM presented hypoperfusion in bilateral amygdala, which had potential diagnostic efficacy in discriminating CM from NC. The 3D-PCASL could be considered as a simple and effective tool to identify the perfusion status in migraine.
Prevalence and adverse outcomes of frailty in patients with acute myocardial infarction after Percutaneous Coronary Interventions: a systematic review and meta-analysis
Authors: Yu Qian , Guo Dawei , Peng Jianan , Wu Qifei , Yao Yonghuan , Wang Jiang , Ding Mei
Published: July 2022

Objective
To investigate the prevalence of frailty in patients with acute myocardial infarction after percutaneous coronary intervention and the relationship between frailty and adverse outcomes in patients with acute myocardial infarction after percutaneous coronary intervention.
Methods
We searched relevant studies published from database establishment to October 2021 and performed a meta-analysis using stata12.0 software. A random-effects model was used for I2 greater than > 50%; otherwise, a fixed-effects model was used.
Results
There were 274,976 elderly patients. The degree of frailty was assessed using different frailty assessment tools, the most common of which was the Frailty Index Scale. Nine studies investigated the prevalence of frailty in patients with acute myocardial infarction after PCI, with an overall prevalence of 39% (95% CI: 18%-60%, P < 0.001). Six studies included adverse outcomes in frail patients with acute myocardial infarction after PCI, including all-cause mortality (HR = 2.29, 95%CI:1.65–3.16, P = 0.285), re-hospitalization (HR = 2.53, 95% CI: 1.38–4.63), and in-hospital major bleeding (HR = 1.93, 95% CI: 1.29–2.90,P = 0.825).
Conclusion
In patients with acute myocardial infarction after PCI, the frailty prevalence is increased, especially in STEMI. Frailty patients after PCI, acute myocardial infarction is more likely to be associated with worse clinical outcomes, such as death, bleeding, and re-hospitalization.
The molecular fingerprint of stress resilience
Authors: Wlodarczyk Jakub , Baczynska Ewa , Zareba-Koziol Monika , Ruszczycki Blazej , Krzystyniak Adam , Wojtowicz Tomasz , Bijata Krystian , Pochwat Bartlomiej , Magnowska Marta , Roszkowska Matylda , Figiel Izabela , Masternak Julia , Dzwonek Joanna , Worch Remigiusz , Olszynski Krzysztof , Wardak Agnieszka , Szymczak Piotr , Radwanska Kasia , Jaholkowski Piotr , Hogendorf Adam , Filipkowski Robert , Szewczyk B , Bijata Monika
Published: July 2022

Stress resilience is an ability of neuronal networks to maintain their function despite the stress exposure. In this study, we investigate whether stress resilience is an actively developed dynamic process in adult mice. In order to assess the resilient and anhedonic behavioral phenotypes developed after induction the chronic unpredictable stress, we quantitatively characterized the structural and functional plasticity of excitatory synapses in the hippocampus using a combination of proteomic, electrophysiological, and imaging methods. Our results indicate that stress resilience is a dynamic and multifactorial process manifested by structural, functional, and molecular changes in synapses. We reveal that chronic stress influences palmitoylation, whose profiles differ between resilient and anhedonic animals. We also observed that stress resilience is associated with structural compensatory plasticity of the postsynaptic parts of synapses.
How are university students’ paid work associated with their locus of control?
Authors: Chang Grace
Published: July 2022

This study examines whether university students doing paid work during their studies improves their internal locus of control – the belief in one’s ability to have control over their life events. Using longitudinal data on a cohort of English students, I model students’ locus of control production at age 20/21. I find that engagement in paid work, rather than hours spent in work, is positively associated with students’ internal locus of control. Students who work term-time have 0.12 standard deviations greater internal locus of control than students who do not work, and these estimates are driven by female students. Estimates during the holidays are similar, but smaller in magnitude and statistically insignificant. I do not find any non-linearities in hours of work to skills development. Future studies which examine types of student work may further unpack the gendered differences of work during studies.JEL Codes – J24, J22, I23
Establishment and validation of a novel prognostic model for non-virus-related hepatocellular carcinoma
Authors: Jiang Yu , Chen Shulin , Wu Yaxian , Qu Yuanye , Jia Lina , Xu Qingxia , Dai Shuqin , Xue Ning
Published: July 2022

Objective
The incidence of non-virus-related hepatocellular carcinoma (NV-HCC) in hepatocellular carcinoma (HCC) is steadily increasing. The aim of this study is to establish a prognostic model to evaluate the overall survival (OS) of NV-HCC.
Methods
Overall, 261 patients with NV-HCC were enrolled in this study. A prognostic model was developed by using LASSO-Cox regression analysis. The prognostic power was appraised by the concordance index (C-index), and the time-dependent receiver operating characteristic curve (TD-ROC). The Kaplan-Meier (K-M) survival analysis was used to evaluate the predictive ability in respective subgroups stratified by prognostic model risk score. A nomogram for survival prediction was established by integrating prognostic model, TNM stage, and treatment.
Results
According to the LASSO-Cox regression result, number of nodules, lymphocyte-to-monocyte ratio (LMR), prognostic nutritional index (PNI), alkaline phosphatase (ALP), aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio (SLR) and C-reactive protein (CRP) were included for prognostic model construction. The C-index of the prognostic model was 0.761(95%CI: 0.723 ~ 0.799) in the development and 0.795 (95%CI: 0.735 ~ 0.855) in the validation cohort, and its predictive ability better than TNM stage and treatment, the TD-ROC showed similar results. K-M survival analysis showed that NV-HCC patients with low-risk score had a better prognosis (P < 0.05). A nomogram based on prognostic model, TNM stage, and treatment was constructed with sufficient discriminatory power with C-index of 0.78 and 0.85 in the development and validation cohort, respectively.
Conclusion
For NV-HCC, the prognostic model could predict OS benefit for patients, which may be helpful to clinicians to give individualized therapeutic suggestions.
Image Denoising in the Deep Learning Era
Authors: Izadi Saeed , Sutton Darren , Hamarneh Ghassan
Published: July 2022

Over the last decade, the number of digital images captured per day witnessed a massive explosion. Nevertheless, the visual quality of photographs is often degraded by noise during image acquisition or transmission. With the re-emergence of deep neural networks, the performance of image denoising techniques has been substantially improved in recent years. The objective of this paper is to provide a comprehensive survey of recent advances in image denoising techniques based on deep neural networks. In doing so, we commence with a thorough description of the fundamental preliminaries of the image denoising problem followed by highlighting the benchmark datasets and the widely used metrics for objective assessments. Subsequently, we study the existing deep denoisers in the supervised and unsupervised categories and review the technical specifics of some representative methods within each category. Last but not least, we conclude the analysis by remarking on trends and challenges in the development of better state-of-the-art algorithms and future research.
Ensemble Modelling for Predicting the Relation between Bio-psychosocial Signals and Seizures using the Gradient Boosting Method
Authors: Kapoor Bhaskar , Nagpal Bharti
Published: July 2022

In recent years, research in the fields of brain-computer interfacing techniques and related areas are developing at a very rapid rate with the help of exploding of Artificial Intelligence, Machine Learning and Deep Learning. A new concept of Ensemble Learnings has become popular research area among the researchers related to the field of automatic classification of electroencephalograph signals for predication of mental health issues like seizures. However effective feature extraction from EEG and accurately classify them with efficient classifiers is still an important task and attracted wide attention in this area. Therefore in this paper, we presented the detailed mathematical analysis of these methods and Ensemble Learnings based EEG signals classification method for seizures using Extreme Gradient Boosting Model.Time-frequency domain based non-linear features are selected from preprocessed EEG Dataset, and PCA (Principal Component Analysis) is used for dimensionality reduction for features engineering, then optimized feature based training and testing is done for two class classification in ensemble learning method (XGBoost) and Random Forest method. Finally, both models are tested with dataset of University of Bonn, Germany to classify the signals. In addition this paper highlights the Correlation Analysis Methodology to Identify Strong Predictor and Attributes Correlation-based Attribute Ranking for the Feature Engineering which has proved to be more efficient in EEG signals Classification and provide comparative analysis with other existing models for performance evaluation in terms of accuracy, specificity and sensitivity.
Health Care Provision in State Institutions in the Context Of COVID-19
Authors: Pakhnenko Olena , Kulibaba Viktor , Palienko Maksym
Published: July 2022

The main purpose of the research is to analyse the financial provision of health care in public institutions on the example of the State Emergency Service and to develop proposals for improving the medical system of the SES, taking into account the challenges of COVID-19. The paper presents the results of an empirical analysis of the amount of funding for health care facilities outside the structure of the Ministry of Health, on the example of the medical system of the State Emergency Service of the Ministry of Internal Affairs of Ukraine during 2017-2022. At a separate stage of the study, the volume and target of additional funding for health care from the Fund for Combating COVID-19 in 2020 were analysed. The analysis showed a lower level of remuneration of specialists and a worse financial situation of health care facilities subordinated to the Department of Medical and Biological Protection and Occupational Safety of the SES of Ukraine. In order to improve the health protection system of the SES, a number of proposals have been developed, namely: formation of a subdivision for analysis of problematic issues of the SES and legislative work to eliminate the identified shortcomings; digitalization and automation of reporting within the medical system of the SES of Ukraine; coverage of the activities of health care institutions of the SES in the media and social networks; advising and conducting licensing and accreditation of health care institutions of the SES; justification for increasing funding for the medical sector of the SES and increasing the salaries of medical workers; expanding the provision of paid services to the population; search for funding outside the budget of the SES within the national budget and outside the state budget from sources not prohibited by law, involvement of humanitarian and charitable organizations, patrons; maintaining and improving the level of qualification of medical staff, improving information and communication work with staff; conducting training and preparation of medical and support specialists for emergency response activities, conducting interdepartmental and local training with the involvement of specialists from local and international humanitarian organizations. The results of the study can be useful in the development of regulations and legislation in the field of medical care of the SES of Ukraine.
Renewable Energy and Health: Bibliometric Review of Non-Medical Research
Authors: Vakulenko Ihor , Lieonov Hlib
Published: July 2022

Renewable energy has been a top topic for research for decades. Studying this issue is essential based on the need to find effective ways to replace fossil fuels with renewable ones. Climate change is the driver of the transition to renewable energy. And suppose the reason for the need to switch to renewable energy is clear to everyone. The methods provoke significant discussions, which have not stopped for a moment since the beginning of research on this topic. The economic aspect of replacing fossil fuels with renewables is paramount to developing effective business models that allow for the rapid replication of good practices. To this end, various mechanisms of state support and the formation of market incentives for investors were tested. However, the issue of the cost-effectiveness of fossil fuel substitution remains problematic. The issue of energy substitution cannot be considered solely in the economic sphere. The reason for this is the significant number of hidden or indirect effects that are difficult to evaluate. However, this needs to be done to understand renewable energy development’s true efficiency and importance. The global impact of large-scale renewable energy technologies is to reduce climate change loss. One of the most important aspects to study and quantify is the impact of energy and public health. It is well known that fossil fuels, being environmentally dirty, harm the human habitat. Declining environmental quality directly affects the number of diseases and life expectancy. Many studies have focused on approaches and quantifying economic losses due to environmental degradation. However, the question of how renewable energy reduces these losses remains poorly studied. Most research on the impact of energy on the environment focuses on reducing emissions. Such studies are extremely valuable but do not allow us to conclude the direct effects of fossil fuel substitution on renewable energy on human life and health and quantify this impact accordingly. This article focuses on the current state of research on the impact of renewable energy on the lives and health of the population and the costs associated with it. Based on available research, the article reviews the scientific developments on this topic in publications, mainly non-medical profiles.
Media Au-Vi Berbasis PowerPoint dalam Pembelajaran Daring Bahasa Indonesia
Authors: Indonesia Tadris Bahasa , Febriyanti Beby Dwi , Mulyaningtyas Rahmawati
Published: July 2022

Learning Indonesian Language nowadays is a challenge for both teachers and students. This condition certainly requires a media to be an intermediary between teachers and students in online and offline learning. Especially, the media that functions as a messanger or delivers the materials from the teacher to students in learning Indonesian language. This media is needed to support Indonesian language learning so that the target is achieved as planned. The objectives of this research include (1) the procedure for making PowerPoint-based Au-Vi media, (2) the factors that influence the making of PowerPoint-based Au-Vi media. This research uses a qualitative method. The process of data analysis of this research is expressed descriptively. The results show that the process of making PowerPoint-based Au-Vi media tends to be easy if the teacher is proficient in using Microsoft PowerPoint. Teachers can create templates, insert learning materials, insert voice explanations for material, add back sounds, set automatic transitions and animations, and save them in MP4 video format. There are two factors that influence the making of this media, namely factors related to the learning components and technical factors outside the learning components.
Implementasi Perkuliahan Keterampilan Berbahasa secara Daring
Authors: Indonesia Tadris Bahasa , Maulida Siti Zumrotul , Kusumawati Hesty
Published: July 2022

Online lectures demand creativity in all respects for both the teachers and the learners. In lecturing,  Indonesian language skills for the collegians in Teacher Education at the Islamic State Islamic School (PGMI) major UIN Sayid Ali Rahmatullah Tulungagung (UIN SATU), especially during the Final Semester Examination (UAS), certain methods are needed so that the main objectives of the lecture can be achieved. At UAS Even of 2020/2021, collegians practice the results of attending Indonesian Language Skills lectures for one semester by teaching the Language Skills to  elementary (MI/SD) students who live around their homes. The results of practicing these skills are made in the form of a report. Furthermore, the results of the report are used as a source of data in the form of documents and will be analyzed through the Miles and Huberman model (Sugiyono, 2016). The type of research used in this research is literature study by tracing several references in the library. The data findings will be discussed in accordance with online learning innovations (Harmanto, 2020). The results showed a positive response from parents and students. In addition, there are also several obstacles, including students who do not focus on learning, are not serious, are anxious, and so on.
Bulut Mutfakların Kurulum Adımları, Çalışma Şekli ve Modelleri (Installation Steps, Operations and Models of Cloud Kitchens)
Authors: Saygı Birol , Ceylan Zafer
Published: July 2022

Artan rekabet ve sürekli gelişen teknoloji ile gıda endüstrisi her zaman çoklu teknolojik yeniliklerle beslenmektedir. Bu bağlamda, bulut mutfak, son zamanlarda gıda endüstrisine gizlice giren ve küresel restoran endüstrisinin önemli bir konsepti haline dönüşmektedir. Bulut mutfağı, fiziksel alanı, yemek yeme alanı veya paket servis tezgâhı olmayan bir restoran konseptidir. Bir başka ifade ile geleneksel bir restoran veya yemek yeme tesisi olmadan sadece teslimat siparişlerini kabul eden bir restoran mutfağıdır. Sadece bir üretim birimi olarak işlev gören yemeklerin hazırlanması için operasyonel bir mutfaktır. Müşteriler, çevrimiçi gıda toplayıcı uygulamaları veya restoran uygulaması aracılığıyla siparişlerini çevrimiçi olarak verebilir. Bu mutfaklar hayalet mutfaklar, karanlık mutfaklar veya sanal mutfaklar olarak da bilinir. Çalışmada günümüzde giderek yaygınlaşan teslimat segmentinin potansiyelini göz önünde bulundurarak, bir bulut mutfağının nasıl çalıştığını, iş modelini, avantajlarını, dezavantajlarını ve dikkate alınması gereken diğer faktörler ile açıklanmaktadır. Kurulumunda hangi tip bulut mutfak kullanılacağı ve bunların parametreleri önemli rol oynamaktadır. Ayrıca, kuşakların yönelimleri ve tüketici davranışları özellikle gelecek on yıl içerisinde bulut mutfak uygulamaları ve kullanımda anahtar bir rol oynayacaktır.