bluuebunny/crossref_metadata_2025 huggingface dataset:
In Defense of Food Curriculum: A Mixed Methods Outcome Evaluation in Afterschool
Authors: Luesse Hiershenee B. , Luesse Joseph E. , Lawson Jordan , Koch Pamela A. , Contento Isobel R.
Published: March 2019

Background. Highly processed foods are inexpensive and abundant in our food supply, nutritionally poor, and disproportionately marketed to minority youth. This study is part of a curriculum development project to develop, implement, and evaluate the In Defense of Food (IDOF) curriculum designed to increase intake of whole/minimally processed foods and decrease intake of highly processed foods in youth. Aims. This pilot outcome evaluation was undertaken to assess initial effectiveness and to provide an in-depth understanding of changes in behavioral outcomes and psychosocial mediators. Methods. We used an explanatory mixed method approach, including a single-arm pretest–posttest of intervention effect, followed by a food rules assessment and in-depth interviews to describe participant responses to the intervention in more detail. The study was conducted in three afterschool classrooms in urban low-income neighborhoods with 32 multiethnic middle-school youth, receiving 10 weekly 2-hour sessions. Results. Two weeks postintervention, there was a large positive significant increase in whole/minimally processed food intake ( p < .01; d = 0.59) and a small decrease in consumption of highly-processed foods ( p = ns; d = 0.06), compared with baseline. Significant increases in psychosocial mediators: Self-efficacy and positive outcomes expectations were seen; others were not significant but changed in the desired direction. Qualitative assessments suggest that the intervention promoted skill building, but environmental barriers made these difficult to use. Discussion. The IDOF curriculum may be most effective for promoting consumption of fruits and vegetables, rather than decreasing intake of highly processed foods. In addition, in this young age-group, short actionable food rules may support self-regulation and behavior change. Conclusion. Among adolescent students in low-income urban neighborhoods, the IDOF afterschool curriculum may help promote self-efficacy and positive outcome expectancies and increase fruit and vegetable intake. Focusing on food processing and using “Food Rules” may be promising to elicit behavior change in youth; however, greater supports are needed to overcome social and environmental barriers.
Retrospective evaluation of risk factors and treatment outcome predictors in cats presenting to the emergency room for constipation
Authors: Benjamin Sarah E , Drobatz Kenneth J
Published: March 2019

Objectives

Constipation is a common complaint in cats presenting to the emergency room and can become a frustrating recurrent condition. Despite widespread anecdotal reports of risk factors for constipation, at the time of writing there have been no studies supporting these associations or assessing treatment outcomes. The aim of this study was to identify risk factors in the signalment, history, physical examination and clinicopathologic findings of cats presenting to the emergency room for constipation. In addition, we aimed to assess factors contributing to the success or failure of enemas administered to these cats.

Methods

A medical record search identified 189 cats with a diagnosis of constipation/obstipation that were treated and discharged by the emergency service at an academic veterinary hospital. Data regarding signalment, medical history, physical examination and clinicopathologic findings, as well as treatments performed, were recorded. Ninety-nine cats presenting to the emergency room for other reasons were identified as controls. Statistical analysis was performed to assess risk factors for constipation, as well as success/failure of enema treatments.

Results

Older, overweight cats and cats with chronic kidney disease or previous episodes of constipation were found to be at increased risk of constipation ( P <0.0001, P = 0.0004, P = 0.0046 and P <0.0001, respectively). Ionized calcium levels were significantly higher in constipated cats, though varied significantly within the cohort ( P = 0.0133). Cats noted to be painful on abdominal palpation were less likely to defecate following an enema. Adjunctive treatments (fluids, laxatives) increased the likelihood of a successful enema but were not statistically significant.

Conclusions and relevance

Older, overweight cats with a history of constipation or chronic kidney disease are more likely to present for constipation. Further studies are needed to determine the most appropriate treatment protocol in an urgent care setting.
Effect of a maximal treadmill test on intraocular pressure and ocular perfusion pressure: The mediating role of fitness level
Authors: Vera Jesús , Jiménez Raimundo , Redondo Beatríz , García-Ramos Amador , Cárdenas David
Published: March 2019

Objectives:

We compared the impact of a maximal treadmill test on intraocular pressure and ocular perfusion pressure between trained and untrained individuals.

Methods:

Based on the maximal aerobic capacity (relative VO2 max), 31 military helicopter pilots were divided into groups of trained (n = 16; VO2 max = 57.06 ± 1.66) and untrained (n = 15; VO2 max = 43.42 ± 1.19) individuals. Intraocular pressure and blood pressure were collected before effort, just after volitional exhaustion and after 5 and 15 min of recovery.

Results:

The maximal treadmill test induced significant changes on intraocular pressure (p < 0.001, η2 = 0.52) and ocular perfusion pressure (p < 0.001, η2 = 0.60). Intraocular pressure and ocular perfusion pressure increased just after volitional exhaustion (effect size = 0.88 and 1.59, respectively), and these values returned to baseline levels after 5 (effect size = 0.87 and 1.26, respectively) and 15 (effect size = 1.23 and 1.91, respectively) min of recovery. The untrained group exhibited higher intraocular pressure and ocular perfusion pressure values in comparison with the trained group just after volitional exhaustion (effect size = 1.43 and 0.11 for intraocular pressure and effect size = 2.81 and 0.96 for ocular perfusion pressure). Five minutes of recovery was insufficient to reach baseline intraocular pressure and ocular perfusion pressure values only for the untrained group (effect size = 0.91 and 0.72, respectively).

Conclusion:

Our findings reveal that fitness level modulates the intraocular pressure and ocular perfusion pressure responses to a maximal treadmill test, being high fitness levels desirable in order to attenuate the impact of maximal efforts on these indices. These outcomes may be of clinical relevance for the management of glaucoma patients or those at risk, although future studies are needed to test these results in a clinical population.
Comparison of performance between two microcatheter systems in ab externo canaloplasty: A retrospective comparison study
Authors: Vastardis Iraklis , Kontopoulou Kalliopi , Fili Sofia , Gatzioufas Zisis , Kohlhaas Markus
Published: March 2019

Purpose:

To compare the performance of two different microcatheter systems, iTrack™ 250A and Glaucolight, in ab externo canaloplasty in three major categories: intraocular pressure reduction, drug therapy reintroduction, and evaluation of viscodilation over distension of the inner wall of Schlemm’s canal.

Methods:

A total of 56 and 46 eyes from different glaucoma types underwent ab externo canaloplasty using two different microcatheter systems. Group formation was made according to microcatheter system used. Kaplan–Meier test was performed for drug therapy reintroduction in relation to the two microcatheters. Tests of between-subject effects in two-way analysis of variance evaluated the efficacy of the two microcatheters and their features in relation to intraocular pressure reduction.

Results:

Kaplan–Meier test was not statistically significant (p = 0.20) regardless of microcatheter system. Tests of between-subject effects in relation to intraocular pressure reduction was not statistically different between the two microcatheters (p = 0.26) or between microcatheter and follow-up (p = 0.90). Intraocular pressure reduction in different glaucoma type was statistically significant during the follow-up period and glaucoma types showed different results between them in relation to follow-up (p < 0.001 and p = 0.002, respectively), but the pairwise comparison was not statistically important (p = 0.42). Intraocular pressure reduction was better in pseudophakic eyes in comparison with phakic eyes (p = 0.03), but the selection of microcatheter seemed not to affect this result (p = 0.11 and p = 0.32, respectively).

Conclusion:

Both microcatheter systems performed equal in terms of intraocular pressure reduction. Drug therapy reintroduction was not affected by the selection of the two microcatheters. Different types of glaucoma responded different to canaloplasty. Pseudophakic eyes responded better to treatment than phakic eyes, but the microcatheter selection seemed not affect this result.
Endophthalmitis associated with fungal keratitis and penetrating injuries in North China
Authors: Liu Meng-Yang , Zhang Li , Yin Xiao-Lin , Sun Shi-Ying
Published: March 2019

Purpose:

To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China.

Methods:

The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao University from January 2012 to December 2016 were reviewed.

Results:

A total of 39 eyes (39 patients) were identified over a 5-year period. Exogenous fungal endophthalmitis was associated with penetrating trauma in 22 eyes (56.4%), fungal keratitis in 15 eyes (38.5%), and intraocular surgery in 2 eyes (5.1%). Hyphae were found in 29 of 37 smear samples (78.4%) by direct microscopic examination. Fungal pathogens cultured from 39 samples were identified as 10 genera and 15 species. Filamentous fungi (molds) accounted for 94.9% (37 samples), including Fusarium (19, 48.7%) and Aspergillus (11, 28.2%). Most keratitis cases were caused by Fusarium (11 of 15; 73.3 %). Aspergillus was isolated from nine penetrating ocular trauma cases (9 of 22; 40.9%). Three eyes receiving evisceration had fungal and bacteria coinfection (3 of 39, 7.7%) with Aspergillus and Bacillus. At least, one surgical intervention was performed in all 39 eyes and 28 (71.8%) eyes underwent two or more procedures, including surgeries and intraocular injections. Twenty-nine patients received intraocular antifungal therapy with amphotericin B and/or voriconazole. Visual acuity at discharge from the hospital was significantly better than the initial visual acuity ( p < 0.001). Final vision of 20/400 or better was achieved in 22 (56.4%) eyes.

Conclusions:

This study highlighted the differences between clinical categories of exogenous fungal endophthalmitis. Trauma was the major etiological factor. Molds were the most common pathogens, with Fusarium ranking first, followed by Aspergillus. Fungal and bacterial coinfection mostly occurred after metal penetrating trauma, and Bacillus was the primary bacterial pathogen. Coinfection may be one reason of evisceration. Immediate intravitreal antifungal therapy combined with vitrectomy was effective for exogenous fungal endophthalmitis. Amphotericin B and voriconazole were commonly used antifungal agents.
Effect of pelvic tilt and rotation on cup orientation in standing anteroposterior radiographs
Authors: Yun Ho Hyun , Murphy William S , Ward Daniel M , Zheng Guoyan , Hayden Brett , Murphy Stephen B
Published: March 2019

Background:

Individual pelvic tilt and rotation have wide variability that can affect the measurement of cup orientation in anteroposterior (AP) radiographs. The purpose of this study was to analyse the effect of pelvic tilt and rotation on radiographic measurements of cup orientation.

Methods:

A total of 53 patients (63 hips) were included in this study. The patients underwent a computed tomography study with standing AP pelvis radiographs taken both preoperatively and approximately 3 months postoperatively. We used 2-dimensional/3-dimensional matching to measure the pelvic tilt and rotation, and the non-standardised and standardised cup orientation.

Results:

There was no difference in the pelvic tilt and rotation between the preoperative and postoperative radiographs. The distribution of the differences between the non-standardised and standardised cup anteversion exhibited a change within 5° in only 34/63 (54%) hips. The pelvic tilt correlated with the difference between the non-standardised and standardised cup anteversion, but the pelvic rotation did not. When all 63 hips were separated into the right and left sides, the pelvic rotation inversely correlated with the pelvic tilt-adjusted difference between the non-standardised and standardised cup anteversion of the right side but directly correlated with that of the left side.

Conclusions:

The current study demonstrated that the measurement of cup anteversion in standing AP radiographs is significantly affected by both the pelvic tilt and pelvic rotation. An improved understanding of the pelvic orientation may eventually allow for desired cup positioning on a patient-specific basis to potentially reduce complications associated with the malposition of the cup.
The rising use of total hip arthroplasty for femoral neck fractures in the United States
Authors: Stronach Benjamin M , Bergin Patrick F , Perez Jorge L , Watson Shawna , Jones LaRita C , McGwin Gerald , Ponce Brent A
Published: March 2019

Background:

We examined the trends in the treatment of femoral neck fractures with arthroplasty in the United States from 2004–2013.

Methods:

We used the National Inpatient Sample database in conjunction with codes from the International Classification of Diseases, Ninth Revision, to identify patients receiving hemiarthroplasty (HA) or total hip arthroplasty (THA) for the treatment of closed femoral neck fracture from 2004–2013. We evaluated the trend of these 2 treatments along with demographics, comorbidities, length of stay and same admission mortality.

Results:

Our study identified 1,059,414 patients who underwent arthroplasty for the treatment of femoral neck fracture. We found a 42% increase in the use of THA during the study period from 8.4% in 2004 to 12.9% in 2013. While the large majority of patients received HA (87.1%), there was an overall decline in the use of HA (89,132 in 2004 to 85,635 in 2013) and increase in the use of THA (8,177 in 2004 to 11,375 in 2013). Patients receiving THA were younger (mean age 74.7 THA vs. 80.4 HA, p < 0.001) with fewer comorbidities, higher likelihood of discharge to home (24% THA vs. 10% HA, p < 0.001) and lower inpatient mortality rates (1.5 % THA vs. 2.4 % HA, p < 0.001) in comparison to HA.

Conclusion:

There has been a significant increase in the use of THA over the last decade. Patients receiving THA were younger and healthier with fewer comorbidities, less likely to sustain a same admission mortality and more likely to discharge to home in comparison to HA patients.
Sphenoid Sinus Cholesteatoma—Complications and Skull Base Osteomyelitis: Case Report and Review of Literature
Authors: Kanjanawasee Dichapong , Chaowanapanja Pattraporn , Keelawat Somboon , Snidvongs Kornkiat
Published: March 2019

Introduction:

Cholesteatoma of the paranasal sinuses is uncommon. Its clinical characteristics are an expanding growth of the affected paranasal sinuses consisting of keratinizing squamous epithelium with bony wall destruction. Among involved paranasal sinuses, sphenoid sinus cholesteatoma is the least common.

Case presentation:

An 82-year-old female diabetic patient presented with subacute onset of fever after experiencing chronic progressive headaches for more than 20 years. Nasal endoscopy found purulent discharge from left sphenoethmoidal recess. Computed tomography (CT) scan of the paranasal sinus showed soft tissue lesions that totally filled the left sphenoid sinus with posterior and inferior wall destruction. There was no evidence of connection to the left mastoid cavity.

Management and outcome:

Left sphenoidotomy was performed. Histopathology revealed cholesteatoma. Two months after surgery, she became worse and CT showed extensive skull base destruction. The patient underwent bilateral sphenoidectomy and craniotomy with surgical debridement of osteomyelitis of the skull base. She received long-term intravenous ertapenam and sitafloxacin for treating drug-resistant Klebsiella infection. The osteomyelitis could not be controlled, and she died.

Discussion:

Progressive headache can be caused by an uncommon disease such as sphenoid sinus cholesteatoma, which is a surgical condition. Complicating osteomyelitis of the skull base requires extensive debridement surgery and should be anticipated.
Mixed pricing strategies in museums: Examining the potential of voluntary contributions for capturing consumer surplus
Authors: Neuts Bart
Published: March 2019

Existing pricing strategies at museums rarely reflect actual market demand. This article compares willingness to pay with paid entrance fees to establish consumer surplus and investigates whether voluntary contributions can serve to capture part of this surplus. A donation box is tested under various design experiments to identify best-performing contribution mechanisms. The proposed method is tested at the New Zealand Maritime Museum, with data collected via an intercept visitor survey and through electronic donation box counters. While the results indicate the existence of a significant consumer surplus, practically none of this surplus was gathered via voluntary contributions, and under normal circumstances less than 1% of museum visitors offered a donation. An animated donation box increased donations to 2% but remained well below the percentage of visitors that claimed to have a positive consumer surplus. The findings conclude that pay-what-you-want principles seem to have limited potential in mixed pricing strategy environments.
Popular music, digital technologies and data analysis: New methods and questions
Authors: Hamilton Craig
Published: March 2019

This article explores how respondents to The Harkive Project ( www.harkive.org ) are enfolding streaming services and automated recommendation systems into their everyday music reception practices. Harkive is an online project running annually on a single day in July that invites people to provide detail and reflection on their experiences with music. Since the project first ran in 2013, it has gathered over 10,000 individual entries. It is conceived as an ongoing experiment in research methodology that attempts to produce an online social space that encourages reflection from respondents about the detail of their music reception practice, while simultaneously acting as a place able to replicate commercial practices around data collection and analysis. This article will demonstrate how such a research process can produce rich descriptive data from respondents who provide a useful snapshot of contemporary music reception practice. The article begins with an overview of how streaming services, data collection from numerous online channels and automated recommendation systems interrelate, and how together they raise questions around how people engage in acts of music reception. It then describes how Harkive is based on similar types of computational/algorithmic processing to those used by key players in the digital music space. The analysis that follows shows that although respondents are engaging in everyday use of streaming services and dynamic recommendations, this engagement tends to be spread across a variety of online channels used in differing combinations, and that it is often recommendations from ‘traditional’ routes, such as media outlets (newspapers, radio stations) and users’ own social groups, that feature prominently in respondent descriptions. Indeed, what Nowak (2016) calls the ‘affective’ element of recommendation appears to be rooted in existing practices that are still in the process of being transposed to the relatively recently emerged digital platforms, rather than – and sometimes in spite of – the rhetorical framing of those platforms as key sites for recommendation and discovery by the companies who operate them. Through a discussion of those findings, and based on an update of Michael Bull’s concept of ‘auditory nostalgia’ (2009), it is then suggested that examining how listeners are enfolding the new technologies of music reception into their everyday routines and routes to meaning-making may be a useful direction for future research. The article then suggests that a mode of working where scholars attempt to reflexively harness data-derived processes may be useful in producing that work, and that experimental and practice-led approaches could enable popular music scholars and listeners alike to develop better epistemic responses to the data-related technologies that have recently helped bring about such huge changes in our everyday music reception practice.
Retrospective comparison of ultrasound facilitated catheter-directed thrombolysis and systemically administered half-dose thrombolysis in treatment of pulmonary embolism
Authors: Sharifi Mohsen , Awdisho Alan , Schroeder Bethany , Jiménez José , Iyer Priya , Bay Curt
Published: March 2019

This study retrospectively compared the outcomes of patients who received ultrasound facilitated catheter-directed thrombolysis (UFCDT) versus systemically administered ‘half-dose’ thrombolysis (HDT) in 97 patients with PE. The outcomes assessed included changes in baseline pulmonary artery systolic pressure (PASP), right ventricle/left ventricle ratio (RV/LV), cost and duration of hospitalization, death, bleeding, and recurrent venous thromboembolism in the short and intermediate term follow-up. Analyses were performed using a covariance adjustment propensity score approach to address baseline differences between groups in variables associated with PASP and RV/LV, covarying baseline scores. The baseline mean ± SE PASP dropped from 49.3 ± 1.1 to 32.5 ± 0.3 mmHg at 36 hours in the HDT group, and from 50.6 ± 1.2 to 35.1 ± 0.4 mmHg in the UFCDT group; group × time interaction p-value = 0.007. Corresponding drops in the RV/LV were from a baseline of 1.26 ± 0.05 to 1.07 ± 0.01 in the HDT group and from 1.30 ± 0.05 to 1.14 ± 0.01 in the UFCDT group at 36 hours; group × time interaction p-value = 0.269. Statistically significant decreases were noted in PASP and RV/LV for both the HDT and UFCDT at 36 hours and follow-up. PASP through follow-up was significantly lower in the HDT than the UFCDT group. Likewise, RV/LV was lower in the HDT group. The duration and cost of hospitalization were lower in the HDT group (6.2 ± 1.4 days vs 1.9 ± 0.3 days, p < 0.001; US$12,000 ± $3000 vs $74,000 ± $6000, p < 0.001). We conclude that both UFCDT and HDT lead to rapid reduction of PASP and RV/LV, whereas HDT leads to a lower duration and cost of hospitalization.
National trends and outcomes for extra-corporeal membrane oxygenation use in high-risk pulmonary embolism
Authors: Elbadawi Ayman , Mentias Amgad , Elgendy Islam Y , Mohamed Ahmed H , Syed Mohammed HZ , Ogunbayo Gbolahan O , Olorunfemi Odunayo , Gosev Igor , Prasad Sunil , Cameron Scott J
Published: March 2019

Little is known about the temporal trends and outcomes for extra-corporeal membrane oxygenation (ECMO) in patients with high-risk pulmonary embolism (PE) in the United States. We queried the National Inpatient Sample (NIS) database from 2005 to 2013 to identify patients admitted with high-risk PE. Our objective was to determine trends for ECMO use in patients with high-risk PE. We also assessed in-hospital outcomes among patients with high-risk PE receiving ECMO. We evaluated 77,809 hospitalizations for high-risk PE. There was an upward trend in the utilization of ECMO from 0.07% in 2005 to 1.1% in 2013 ( p = 0.015). ECMO was utilized more in urban teaching hospitals and large hospitals. ECMO use was associated with lower mortality in patients with massive PE ( p < 0.001). In-hospital mortality for patients receiving ECMO was 61.6%, with no change over the observational period ( p = 0.68). Our investigation revealed several independent predictors of increased mortality in patients with high-risk PE using ECMO as hemodynamic support, including: age, female sex, obesity, congestive heart failure, and chronic pulmonary disease. ECMO, therefore, as a rescue strategy or bridge to definitive treatment, may be effective in the management of high-risk PE when selecting patients with favorable clinical characteristics.
“A slow and unrewarding and miserable pause in your life”: Waiting in medicalized gender transition
Authors: Pitts-Taylor Victoria
Published: March 2019

Waiting is a common experience in medicalized gender transition. In this article, I address subjective experiences of medicalized gender transition through a temporal lens, focusing on personal narratives of wait lists, setbacks, and other delays experienced by trans patients. I consider administered waiting as a biopolitical practice of governance, one that has subjectifying and somatic effects on individuals and that speaks to the role of time in the administration of bodies, sex/gender, and biomedical citizenship. I ground my discussion in narratives created by trans people that chronicle their gender transitions; I analyze a set of gender transition vlogs appearing on YouTube, focusing on temporal aspects of medicalized transition and experiences of waiting. My discussion recognizes that the temporal modes of gender transition are multivalent, but these social media narratives also suggest being made to wait is an experience of power relations, one that is capable of producing submission, weariness, and precarity.
Love and hate at the Cultural Interface: Indigenous Australians and dating apps
Authors: Carlson Bronwyn
Published: March 2019

Social media is increasingly entangled in our everyday lives, and it appears inevitable that this trend will continue for the foreseeable future. Although there has been a wellspring of research on social media, very little is known about Indigenous Australians’ use of these online communication channels. Similarly, there is a paucity of research that investigates the links between social media and intimacy. This article explores Indigenous use of dating applications for ‘hooking up’ and engaging in online romances, and investigates the incidence of ‘sexual racism’ that is often directed at Indigenous online users of romance social media platforms.
Benchmark between Bosch and Zeuch method–based flowmeters for the measurement of the fuel injection rate
Authors: Ferrari Alessandro , Zhang Tantan
Published: March 2019

Bosch and Zeuch method–based flowmeters use the pressure rise triggered by the injection event in a different way in order to characterize the injected flow-rate time history. These typologies of measurement are the most widely applied to evaluate the injection rate of fuel injection systems. The injection rate of a Common Rail electroinjector has been measured with both Bosch and Zeuch method–based flowmeters. The objective has been to perform a benchmark on these two different flow-rate measuring principles. A slight reduction in the rising slope of the injected flow-rate, an anomalous tail at the end of the injection and a time delay in the flow-rate trace have been observed in the case of the Bosch method measurement. A one-dimensional numerical model of the hydraulic circuit of the flowmeter based on the Bosch method has been developed and validated successfully. This model has then been applied to study the cause and effect relationships between the features of the flowmeter hydraulic circuit and the alteration in the measured injected flow-rate pattern. Design keys for the optimization of the Bosch-based flowmeters are provided, even though the investigation has definitely assessed the superior accuracy of Zeuch method–based flowmeters, at least for the examined working conditions.
A Bayesian transition model for missing longitudinal binary outcomes and an application to a smoking cessation study
Authors: Li Li , Lee Ji-Hyun , Sutton Steven K , Simmons Vani N , Brandon Thomas H
Published: March 2019

Smoking cessation intervention studies often produce data on smoking status at discrete follow-up assessments, often with missing data in different amounts at each assessment. Smoking status in these studies is a dynamic process with individuals transitioning from smoking to abstinent, as well as abstinent to smoking, at different times during the intervention. Directly assessing transitions provides an opportunity to answer important questions like ‘Does the proposed intervention help smokers remain abstinent or quit smoking more effectively than other interventions?’ In this article, we model changes in smoking status and examine how interventions and other covariates affect the transitions. We propose a Bayesian approach for fitting the transition model to the observed data and impute missing outcomes based on a logistic model, which accounts for both missing at random (MAR) and missing not at random (MNAR) mechanisms. The proposed Bayesian approach treats missing data as additional unknown quantities and samples them from their posterior distributions. The performance of the proposed method is investigated through simulation studies and illustrated by data from a randomized controlled trial of smoking cessation interventions. Finally, posterior predictive checking and log pseudo marginal likelihood (LPML) are used to assess model assumptions and perform model comparisons, respectively.
Patient empowerment and its correlates in young persons with congenital heart disease
Authors: Acuña Mora Mariela , Sparud-Lundin Carina , Burström Åsa , Hanseus Katarina , Rydberg Annika , Moons Philip , Bratt Ewa-Lena
Published: March 2019

Objective:

The objective of this study was to measure the level of empowerment and identify its correlates in young persons with congenital heart disease.

Study design:

Patients aged 14–18 years with congenital heart disease, and under active follow-up in one of four paediatric cardiology centres in Sweden were invited to participate in a cross-sectional study. A total of 202 young persons returned the questionnaires. Patient empowerment was measured with the Gothenburg Young Persons Empowerment Scale that allows the calculation of total and subscale scores. Univariate and multivariate linear regression analyses were undertaken to analyse possible correlates, including: sex, age, health behaviours, knowledge of congenital heart disease, quality of life, patient-reported health, congenital heart disease complexity, transition readiness and illness perception.

Results:

The mean empowerment score was 54.6±10.6 (scale of 15–75). Univariate analyses showed that empowerment was associated with age, quality of life, transition readiness, illness perception, health behaviours and patient-reported health (perceived physical appearance, treatment anxiety, cognitive problems and communication issues). However, multivariable linear regression analyses identified that only transition readiness (β=0.28, P<0.001) and communication (β=0.36, P<0.001) had a positive association with patient empowerment. These variables were also significantly associated with the subscale scores of the empowerment scale of knowledge and understanding ( P<0.001), shared decision-making ( P<0.001) and enabling others ( P<0.01). The overall models’ explained variance ranged from 8% to 37%.

Conclusion:

Patient empowerment was associated with transition readiness and fewer problems communicating. While it is not possible to establish the directionality of the associations, interventions looking to increase empowerment could benefit from using these variables (or measurements) for evaluation purposes.
Demagnetization-based axial magnetized magnetostrictive patch transducers for locating defect in small-diameter pipes using the non-axisymmetric guided wave
Authors: Fang Zhou , Tse Peter W
Published: March 2019

The propagation of the non-axisymmetric guided wave in the small-diameter pipe is complicated, which makes the circumferential position of the defect difficult to be determined. This article reports on the design of a segmented axially magnetized magnetostrictive patch transducer array for efficient transduction of non-axisymmetric L(M,2) modes to determine defect’s axial and circumferential positions in the small-diameter pipe. First, the background of the magnetostrictive patch transducer and non-axisymmetric guided wave in the pipe was presented. Moreover, the theoretical background to the influence of the length-to-width ratio of the magnetized rectangular patch on the demagnetizing factors was introduced. Second, the method of the pipe health monitoring using the designed segmented axially magnetized magnetostrictive patch transducer array was proposed. Third, the most suitable multi-belts of the flexible printed coils were chosen to provide the dynamic magnetic field by the comparison experiments. Then the signal amplitudes of the segmented axially magnetized magnetostrictive patch transducer array with different length–width ratios of magnetostrictive materials were compared with each other to prove the principle of demagnetization. Another two magnetostrictive patch transducer arrays employing permanent magnets were compared with the proposed segmented axially magnetized magnetostrictive patch transducer array. The experiments of pipe health monitoring were carried out to prove that the proposed method can realize pipe health monitoring over time. Fourth, the defect orientation experiments in a 304 stainless steel pipe with 48 mm inner diameter and 2 mm thickness were performed using the proposed segmented axially magnetized magnetostrictive patch transducer array at 650 kHz. The prediction of the circumferential position of the defects correlated well with the defect’s true location through matching the angular profiles of the experimental results and the modulated numerical analysis for several axial distances. The experimental results for the segmented axially magnetized magnetostrictive patch transducer array demonstrated that the proposed segmented axially magnetized magnetostrictive patch transducer array could potentially be applied to detect the axial and circumferential positions of the defect in a small-diameter pipe.
Physical Activity Communication: A Scoping Review of the Literature
Authors: Bergeron Caroline D. , Tanner Andrea H. , Friedman Daniela B. , Zheng Yue , Schrock Courtney S. , Bornstein Daniel B. , Segar Michelle , Swift Natalie
Published: March 2019

Engaging in regular physical activity can help prevent chronic disease and enhance quality of life. Unfortunately, less than 20% of American adults meet the recommended physical activity guidelines, perhaps indicating ineffective communication efforts around physical activity. In preparation for the release of the second edition of the Physical Activity Guidelines for Americans, and using the physical activity guidelines as a cornerstone of our approach, we conducted a scoping review of physical activity communication research to understand the scholarly efforts related to communicating about physical activity. Using a social-ecological perspective, we identified studies using the keywords physical activity* OR exercise* AND health communication* in three public health and communication databases and retained studies conducted in the United States and published in English from 1995 through 2015. Sixty-seven articles included a mention of physical activity guidelines, a health communication focus, and media channels used in promoting physical activity. Half of the studies were published in health/science communication journals. One third of the studies mentioned physical activity guidelines. Only 19% of the studies featured mental health benefits of physical activity while more than 64% emphasized physical health benefits. Nearly all the studies (96%) mentioned the use of persuasion to encourage engagement in physical activity. More effort is needed to study the influence of communicating physical activity guidelines to the public. Best practices for future physical activity communication are discussed for both researchers and practitioners.
Non-Cross-Linked Collagen Mesh Performs Best in a Physiologic, Noncontaminated Rat Model
Authors: Kaufmann Ruth , Jairam An P. , Mulder Irene M. , Wu Zhouqiao , Verhelst Joost , Vennix Sandra , Giesen Louis J. X. , Clahsen-van Groningen Marian C. , Jeekel Johannes , Lange Johan F.
Published: March 2019

Background. In laparoscopic incisional hernia repair, direct contact between the prosthesis and abdominal viscera is inevitable and may lead to adhesions. Despite the large variety of mesh prosthesis, little is known about their in vivo behavior. Biological meshes are considered to have many advantages, but due to their price they are rarely used. A rat model was used to assess biological and conventional synthetic meshes on their in vivo characteristics. Design. One-hundred twenty male Wistar rats were randomized into five groups of 24 rats. A mesh was implanted intraperitoneally and fixated with nonresorbable sutures. The following five meshes were implanted: Parietene (polypropylene), Permacol (cross-linked porcine acellular dermal matrix), Strattice (non-cross-linked porcine acellular dermal matrix), XCM Biologic (non-cross-linked porcine acellular dermal matrix), and Omyra Mesh (condensed polytetrafluoroethylene). The rats were sacrificed after 30, 90, or 180 days. Incorporation, shrinkage, adhesions, abscess formation, and histology were assessed for all meshes. Results. All animals thrived postoperatively. After 180 days, Permacol, Parietene, and Omyra Mesh had a significantly better incorporation than Strattice ( P = .001, P = .019, and P = .037 respectively). After 180 days, Strattice had significantly fewer adhesions on the surface of the mesh than Parietene ( P < .001), Omyra Mesh ( P = .011), and Permacol ( P = .027). After 30 days, Permacol had significantly stronger adhesions than Strattice ( P = .030). However, this difference was not significant anymore after 180 days. After 180 days, there was significantly less shrinkage in Permacol than in Strattice ( P = .001) and Omyra Mesh ( P = .050). Conclusion. Based on incorporation, adhesions, mesh shrinkage, and histologic parameters, Strattice performed best in this experimental rat model.
Responding to terrorism with peace, love and solidarity: ‘Je suis Charlie’, ‘Peace’ and ‘I Heart MCR’
Authors: Eroukhmanoff Clara
Published: March 2019

This article explores the affective responses to terrorist attacks in Western Europe, visually manifested through the memes ‘Je suis Charlie’, ‘Peace’, and ‘I heart MCR’ . By invoking the universal peace and solidarity signs, these responses mobilised an iconic repertoire that framed the responses as peaceful retaliations to terrorist attacks in solidarity with the victims and in that respect, helped to visualise and foster positive emotions in times of crisis. Indeed, the memes were articulated as the antidote (love) that can defy the brutality and hatred of terrorists. This article challenges this view in two ways. First, the article argues that the visual interventions constitute technologies of emotional governance that police subjects about whom to love, to whom solidarity should be extended and when and where those feelings should be displayed. Second, drawing on the work of Gilles Deleuze on Francis Bacon, this article demonstrates that by propagating iconic representations of solidarity, peace and love, ‘meming’ attends to the logic of the sensational and the cliché and thereby falls short of contesting terrorism through sensing peace, love and solidarity. Finally, the article addresses how the violence of sensation can release the invisible forces that can be made productive in celebrating life.
Force and flowfield measurements to understand unsteady aerodynamics of cycloidal rotors in hover at ultra-low Reynolds numbers
Authors: Reed Carolyn M , Coleman David A , Benedict Moble
Published: March 2019

This paper provides a fundamental understanding of the unsteady fluid-dynamic phenomena on a cycloidal rotor blade operating at ultra-low Reynolds numbers (Re ∼ 18,000) by utilizing a combination of instantaneous blade force and flowfield measurements. The dynamic blade force coefficients were almost double the static ones, indicating the role of dynamic stall. For the dynamic case, the blade lift monotonically increased up to ±45° pitch amplitude; however, for the static case, the flow separated from the leading edge after around 15° with a large laminar separation bubble. There was significant asymmetry in the lift and drag coefficients between the upper and lower halves of the trajectory due to the flow curvature effects (virtual camber). The particle image velocimetry measured flowfield showed the dynamic stall process during the upper half to be significantly different from the lower half because of the reversal of dynamic virtual camber. Even at such low Reynolds numbers, the pressure forces, as opposed to viscous forces, were found to be dominant on the cyclorotor blade. The power required for rotation (rather than pitching power) dominated the total blade power.
A parameterised mathematical model to elucidate osteoblast cell growth in a phosphate-glass microcarrier culture
Authors: Burova Iva , Peticone Carlotta , De Silva Thompson David , Knowles Jonathan C , Wall Ivan , Shipley Rebecca J
Published: March 2019

Tissue engineering has the potential to augment bone grafting. Employing microcarriers as cell-expansion vehicles is a promising bottom-up bone tissue engineering strategy. Here we propose a collaborative approach between experimental work and mathematical modelling to develop protocols for growing microcarrier-based engineered constructs of clinically relevant size. Experiments in 96-well plates characterise cell growth with the model human cell line MG-63 using four phosphate glass microcarrier materials. Three of the materials are doped with 5 mol% TiO2 and contain 0%, 2% or 5% CoO, and the fourth material is doped only with 7% TiO2 (0% CoO). A mathematical model of cell growth is parameterised by finding material-specific growth coefficients through data-fitting against these experiments. The parameterised mathematical model offers more insight into the material performance by comparing culture outcome against clinically relevant criteria: maximising final cell number starting with the lowest cell number in the shortest time frame. Based on this analysis, material 7% TiO2 is identified as the most promising.
Sex-related differences in frailty factors in older persons with type 2 diabetes: a cross-sectional study
Authors: Nishimura Akiko , Harashima Shin-ichi , Hosoda Kiminori , Arai Hidenori , Inagaki Nobuya
Published: March 2019

Background:

This cross-sectional study aimed to describe sex-related differences in diabetes-specific factors underlying the development of frailty in older persons with type 2 diabetes.

Methods:

Older persons aged 60–80 years were sequentially enrolled. Frailty and sarcopenia were evaluated using the validated Kihon checklist (KCL) and Asian Working Group for Sarcopenia algorithm, respectively. Physical function and characteristics were measured by trained nurses independently.

Results:

This study included 213 participants. The mean age, body mass index (BMI), and glycated hemoglobin (HbA1c) level were 70.4 years, 24.3 kg/m2, and 7.4%, respectively. Prevalence of frailty was higher in women. Social and cognitive functions were lower in the prefrailty stage, while physical function was lower in the frailty stage, although there was no decrease in skeletal muscle mass. After adjustment for age, the KCL score was significantly associated with peripheral neuropathy, diet score, and coronary artery disease (CAD); frailty, with CAD and inoccupation; prefrailty, with diet score; and sarcopenia, with living alone in men. Meanwhile, the KCL score was significantly associated with living alone and skeletal muscle percentage; prefrailty, with peripheral neuropathy; and sarcopenia, with diabetes duration, LDL-cholesterol level, diet score, and irregular lifestyle in women.

Conclusions:

Sex differences in the risk factors of frailty should be considered when selecting preventive strategies for older persons with type 2 diabetes, early in the prefrailty stage. In particular, it is important to evaluate social participation and diet therapy in men and skeletal muscle mass and psychosocial function in women.
Integration of an electronic Drug Burden Index risk assessment tool into Home Medicines Reviews: deprescribing anticholinergic and sedative medications
Authors: Kouladjian O’Donnell Lisa , Gnjidic Danijela , Chen Timothy F. , Hilmer Sarah N.
Published: March 2019

Background:

Our aim in this research was to establish whether integrating an electronically generated calculation and report on the Drug Burden Index (DBI) in the Home Medicines Review (HMR) setting is an accurate, feasible and useful risk assessment tool to assess risk of anticholinergic and sedative medications; and to establish whether the intervention of DBI together with HMR is associated with a reduced use of anticholinergic and sedative medications in older community-dwelling adults in Australia.

Methods:

An interventional feasibility study was conducted. Accredited clinical pharmacists (APs) were recruited to participate. Each AP was educated on implementation of the DBI into HMR practice and given access to the DBI Calculator© web-based software to generate the DBI report for inclusion in HMR reports for general practitioners (GPs). APs recruited patients (⩾65 years) who were referred to them for HMRs. Patients were sent a letter about their DBI exposure, and a prompt to visit their GP to discuss their medication management options. GPs, APs and patients were asked to evaluate the feasibility and utility of the DBI report. A medication inventory was collected from patients at the time of the HMR and at 3 months to determine whether the intervention affected deprescribing of medications with anticholinergic and sedative effects.

Results:

Regarding the feasibility of the DBI report as a risk assessment tool within HMR, 89% of APs and 67% of GPs agreed that it would be feasible. The DBI Calculator© was potentially inaccurate, as 26% of DBI scores were underestimated and 7% were overestimated (at baseline). At 3 months, the median (interquartile range) DBI for patients ( n = 100) significantly decreased from 0.82 (0–1.33) to 0.67 (0–1.29) ( p = 0.014). Additionally, of patients with a DBI > 0 ( n = 66), 36.4% had their DBI score decrease, and 6.1% had a score increase.

Conclusion:

This study demonstrated that integration of the DBI Calculator© into HMR is a feasible and useful method to prompt deprescribing of anticholinergic and sedative medications in older adults. There is potential for the accuracy of the web-based platform to be improved.

Registration of trial:

Name: Feasibility study of the Drug Burden Index with Home Medicines Review. Website: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=368523 Trial ID: ACTRN 12615000539538.