bluuebunny/crossref_metadata_2025 huggingface dataset:
An Advanced Noise Reduction and Edge Enhancement Algorithm
Authors: Huang Shih-Chia , Hoang Quoc-Viet , Le Trung-Hieu , Peng Yan-Tsung , Huang Ching-Chun , Zhang Cheng , Fung Benjamin C. M. , Cheng Kai-Han , Huang Sha-Wo
Published: August 2021

Complementary metal-oxide-semiconductor (CMOS) image sensors can cause noise in images collected or transmitted in unfavorable environments, especially low-illumination scenarios. Numerous approaches have been developed to solve the problem of image noise removal. However, producing natural and high-quality denoised images remains a crucial challenge. To meet this challenge, we introduce a novel approach for image denoising with the following three main contributions. First, we devise a deep image prior-based module that can produce a noise-reduced image as well as a contrast-enhanced denoised one from a noisy input image. Second, the produced images are passed through a proposed image fusion (IF) module based on Laplacian pyramid decomposition to combine them and prevent noise amplification and color shift. Finally, we introduce a progressive refinement (PR) module, which adopts the summed-area tables to take advantage of spatially correlated information for edge and image quality enhancement. Qualitative and quantitative evaluations demonstrate the efficiency, superiority, and robustness of our proposed method.
The Identification of the Uncertainty in Soil Strength Parameters Based on CPTu Measurements and Random Fields
Authors: Pieczyńska-Kozłowska Joanna , Bagińska Irena , Kawa Marek
Published: August 2021

The present paper responds to the challenge of modeling uncertainty in soil strength parameters concerning its spatial variability in a situation of limited soil information. Understanding this uncertainty allows for the management of the risk of geotechnical structure failure. In the present work, this uncertainty is identified based on signals from the cone penetration test (CPT) device. Signals are directly transformed using existing interpretation methods (typically used as a source of mean values of parameters for a given range of depths) to obtain depth-varying effective strength parameters of the soil. The process is performed by incorporating data from two case studies from different locations in similar soil materials. First, Keswick clay from Australia, for which the results of both CPT and laboratory tests are available, is examined. Second, to further verify the obtained results, the soil from Poland called Świerzna clay, for which only CPT signals were available, is also tested. As shown, the variability of the transformed signals can be a good source of information for identifying uncertainty in soil strength. It agrees well with literature data and can be used to identify random fields describing soil parameters.
Clustering Algorithms on Low-Power and High-Performance Devices for Edge Computing Environments
Authors: Lapegna Marco , Balzano Walter , Meyer Norbert , Romano Diego
Published: August 2021

The synergy between Artificial Intelligence and the Edge Computing paradigm promises to transfer decision-making processes to the periphery of sensor networks without the involvement of central data servers. For this reason, we recently witnessed an impetuous development of devices that integrate sensors and computing resources in a single board to process data directly on the collection place. Due to the particular context where they are used, the main feature of these boards is the reduced energy consumption, even if they do not exhibit absolute computing powers comparable to modern high-end CPUs. Among the most popular Artificial Intelligence techniques, clustering algorithms are practical tools for discovering correlations or affinities within data collected in large datasets, but a parallel implementation is an essential requirement because of their high computational cost. Therefore, in the present work, we investigate how to implement clustering algorithms on parallel and low-energy devices for edge computing environments. In particular, we present the experiments related to two devices with different features: the quad-core UDOO X86 Advanced+ board and the GPU-based NVIDIA Jetson Nano board, evaluating them from the performance and the energy consumption points of view. The experiments show that they realize a more favorable trade-off between these two requirements than other high-end computing devices.
A 12–20 GHz Wideband High-Power SP2T Switch Based on Gap Waveguide Technology
Authors: Alazemi Abdullah J. , Farahbakhsh Ali , Zarifi Davoud
Published: August 2021

A novel wideband high-power single-pole two-throw (SP2T) switch based on gap waveguide technology is presented in this article. The proposed switch has a SP2T structure and consists of three standard WR62 waveguide ports. Due to the advantage of gap waveguide technology, the switch design structure requires no electrical contact between its different parts, and the leakage of the electromagnetic wave is suppressed. The proposed switch has an air gap between its parts. As a result, the sliding part of the switch can be moved freely to change the switch states. Consequently, a low-precision and low-cost fabrication can be utilized. The simulation and measurement of the proposed switch indicate that a 50% operating frequency bandwidth covering the range of 12–20 GHz can be achieved. The switch input return-loss is better than 15 dB within the frequency bandwidth, whereas the insertion loss and isolation levels of the proposed design are above 0.15 dB and better than 65 dB, respectively.
Effects of Strontium Content on the Microstructure and Ionic Conductivity of Samarium-Doped Ceria
Authors: Sherwood Toby , Baker Richard T.
Published: August 2021

Due to its high oxygen ion conductivity at elevated temperatures, samarium-doped ceria (SDC) is a very promising material for application in solid state electrochemical devices and especially in the electrolytes of solid oxide fuel cells. Several prior studies have reported a further improvement in the ionic conductivity of SDC on doping with small amounts of strontium. It is suggested that strontium acts as a sintering aid—improving the microstructure of SDC—and as a scavenger of silicon impurities, decreasing its tendency to form resistive phases at grain boundaries. However, because of the range of preparation methods and the resulting differences in microstructure and silicon levels, some inconsistencies exist in the literature. Furthermore, the effect of strontium on the intrinsic (bulk) conductivity of SDC is not often discussed. To address these issues, a systematic, combined microstructural and conductivity study has been performed on a compositional series with a range of strontium contents, Ce0.8−xSm0.2SrxO2−δ (x = 0, 0.002, 0.005, 0.01, 0.02, 0.03, 0.04). A low temperature synthesis affording products with low silicon was employed. Total bulk and grain boundary conductivity data were obtained over a wide temperature range. Increasing strontium content caused a general decrease in total and intrinsic conductivity, but there was an improvement in grain boundary conductivity at the lowest strontium levels. These results were interpreted by reference to the microstructures using, among other parameters, the blocking, and normalised blocking, factors.
Multiple Adverse Drug Reactions to Calcineurin Inhibitors in a Renal Transplant Patient
Authors: Ahmed Raheel , Hassan Zair , Haseeb Abdul , Masood Aysha , Ali Iftikhar
Published: August 2021

Calcineurin inhibitors (CNIs) are typically used to prevent organ rejection and their use has significantly improved allograft and survival rates with a marked reduction in rejection rates. However, CNIs have been associated with various side effects including nephrotoxicity, hypertension, gingival hyperplasia, hypertrichosis, hepatotoxicity, hyperkalemia, and neurotoxicity. Significant intra-patient and interpatient pharmacokinetic variability and narrow therapeutic indices make the therapy complicated. Although CNIs are essential in preventing organ rejection, higher doses could lead to toxicity, which can reduce patient tolerability and negatively affect long-term allograft survival and patient mortality. As individual patients respond differently to comparable drug levels, attaining the optimal drug level range does not ensure lack of drug toxicity or complete immunosuppressant viability. One to two adverse effects are commonly observed in patients using CNIs. However, no case about CNI-induced gingival hyperplasia, hypertrichosis, tremors, facial nerve palsy, and blepharospasm after kidney transplantation in a single patient has been reported. Our report describes the unusual case of a patient presenting with CNI-induced multiple adverse reactions.
Effect of Low Temperature on Electric Vehicle Range
Authors: Steinstraeter Matthias , Heinrich Tobias , Lienkamp Markus
Published: August 2021

A significant disadvantage of battery electric vehicles compared to vehicles with internal combustion engines is their sharply decreased driving range at low temperatures. Two factors are primarily responsible for this decreased range. On the one hand, the energy demand of cabin heating needs to be supplied by the vehicle’s battery since less waste heat is available from the powertrain, which could be used to cover heating demands. On the other hand, a limited capability to recuperate at low temperatures serves to protect the battery from accelerated aging, which ultimately leads to less energy regeneration. This paper analyzes the impact of both factors separately on a battery electric vehicle’s driving range. Additionally, this paper provides technical requirements for the implementation of an electrothermal recuperation system. Such a system has the potential to reduce the impact of both abovementioned factors on driving range by enabling the direct usage of regeneratable energy for heating when battery charging is limited under cold conditions. The presented analysis is based on BMW i3 and Tesla Model 3 datasets, which combined cover more than 125 trips in and around Munich at different ambient conditions. The results show that the range can decrease by up to 31.9% due to heating and by up to 21.7% due to limited recuperation, which gives a combined maximum range decrease of approximately 50% under cold conditions. Additionally, it was found that a heater with a short reaction time in the lower millisecond range and a power capability of 20 kW would be sufficient for an electrothermal recuperation system to enable the utilization of unused regenerative braking potentials directly for heating.
On economic foundations of the rational organization of production at the plant
Authors: Bukhalkov M.I. , Kuzmin M.A.
Published: August 2021

It reveals the contribution of scientists — pioneers in the development of national science organization of production, the creation of the Russian School of Management.

English version of the article is available at URL: https://panor.ru/articles/economic-basis-of-rational-labour-and-production-organization-at-the-enterprise/65596.html
Crisis in the domestic and world book market: causes and ways to eliminate its consequences
Authors: Butov A.V.
Published: August 2021

Based on the study of world experience in the development of book trade, the author has developed a number of anti-crisis measures to improve the situation and increase the analysis of the structure of sales, growth in prices for book products. Particular attention in the article is paid to the consideration of modern technologies, such as print on demand, self publishing, ensuring the implementation of the foundations of a lean manufacturing system, reducing costs and inventory, as well as the use of digital prints on Internet platforms as a means of effectively combating the distributors of pirated content on the network.
Organizational and Management Innovation: Theory and Practice of Training
Authors: Balakhanova D.K.
Published: August 2021

The training of specialists in the field of management and organizational and managerial innovations is especially relevant in modern conditions, since it is they who contribute to the adoption of competent, competent and modern decisions in the field of management,
Methodological aspects of assessing the impact of corporate values on the development of a company
Authors: Filin S.A. , Sidorova V.N.
Published: August 2021

In the modern world, with all the variety of opportunities for self-realization of employees of companies, corporate values play a special role, which allow both employees and the organization itself to develop and reach a new professional level.
Corporate business strategies according to M. Porter on the example of Tesla
Authors: Movsesyan E.K. , Butov A.V.
Published: August 2021

The article aims to disclose information about Tesla’s corporate strategies through theoretical and practical research of the topic. The theoretical part presents a full-fledged base of information on corporate strategies of M. Porter. In the practical part, the approach to corporate strategies of Tesla company and its change during the life of the company is considered.
Proyecto de ley del código penal de Bolivia para regular interrupción de embarazos inviables
Authors: Camiño Leon Tomás Erik
Published: August 2021

El Artículo 266 del Código Penal de Bolivia tipifica las causas para la interrupción de un embarazo, sin embargoadolece en cuanto a la tipificación de embarazos inviables. Esta investigación tuvo como objetivo dar respuestaa esta problemática a través de una propuesta del Proyecto de Ley de Inclusión de un parágrafo en el Artículo266 que permita regular jurídicamente los casos de embarazos inviables cuando exista el diagnóstico de fetocon anencefalia. Es una investigación proyectiva fundamentada en un diagnóstico de necesidades, con un marcojurídico comparativo en el ámbito internacional y nacional. Para lo cual, se utilizaron las técnicas de la encuesta,la entrevista y el análisis documental. Los instrumentos fueron el cuestionario aplicado a 30 abogados penalistas,la guía de entrevistas realizadas a dos fiscales abogados y el análisis documental de las leyes sobre tipificaciónde embarazos inviables. Se diagnosticó la necesidad de expedir de forma clara y específica normas legales quepermita una adecuada aplicación de los principios constitucionales en Bolivia, en relación con los convenios ytratados internacionales en materias como derechos humanos, derechos sexuales y reproductivos, derechos deniños y adolescentes. Por lo tanto se propone: Art. 1. Agréguese un “parágrafo” al artículo 266 “que incorpore lainterrupción de un embarazo, certificado por un grupo de 3 facultativos la inviabilidad fetal por anencefalia”.
¿Resistencia a la autoridad o ajusticiamiento? Letalidad policial en Venezuela
Authors: Salas Johel , Rujano Raima
Published: August 2021

El objetivo del estudio fue analizar los significados de la letalidad policial a partir del testimomio de los familiares de las víctimas. Metodologicamente, se realizó bajo el enfoque cualitativo. Se utilizó el método relatos de vida. Los resultados arrojaron que los cuerpos policiales en la región zuliana ajustician delincuentes e inocentes, bajo la justificación de “resistencia a la autoridad”. Las conclusiones develaron que las policías en en el estado Zulia se han corrompido, al punto de ser considerados por los entrevistados como “la nueva hampa”, y se han arrogado el derecho de irrespetar la vida de las personas. La violación del debido proceso y del derecho a la vida predomina en los hallazgos de la investigación, en la que los ciudadanos les temen más a los policías que a los delincuentes. Se ha impuesto la pena de muerte, en una abierta transgresión de la normativa legal vigente en Venezuela.
Dynamics of Body Composition, RNA:DNA Ratio and Elemental Concentration of Rohu Labeo rohita (Ham.) in Relation to Stress Induced by Fasting
Authors: ALI M. , SALAM A. , RAZAQ S. , ANSARI T.M.
Published: August 2021

The present study was undertaken to examine composition changes in rohu during feed deprivation. Rohu fingerlings (initial weight =12.86 ± 2.81gm, initial length = 11.26 ± 2.59 cm) were subjected to feed deprivation for 0 (control), 15, 30 and 45 days at temperature of 32 ± 2°C. Results revealed that % water, % ash increased, % organic contents and RNA:DNA ratio decreased significantly while % protein remained fairly constant on percent dry weight basis. Results also revealed that among elements when analyzed on absolute amount basis only calcium was significantly affected by starvation showing linear increase while all other elements showed a trend of increase in initial days of starvation and then decreased later. The overall effect of starvation on sodium, magnesium, zinc and iron was nonsignificant.
Influence of Dietary Intake of Levamisole on Growth and Survival of Macrobrachium rosenbergii (Palaemonidae, de Man)
Authors: BARUAH N. , PRASAD K.P.
Published: August 2021

An inclusive indoor experimental trial was carried out to determine the influence of levamisole, an antihelminthes, as a growth facilitator in the culture of scampi (Macrobrachium rosenbergii, Palaemonidae). A purified diet was prepared with 40% protein, containing levamisole at 0 mg (as control), 125 mg and 250 mg·kg-1 dry weight. Nine plastic tanks were stocked with a group of 32 animals (PL20-30) each and fed the trial diet for three months. Animals were regularly weighed at the end of each month. No significant difference was noticed in mean growth and survival (P > 0.05) of the animals between treatments. However, significant differences (P < 0.05) were observed in the growth parameters like percentage of weight gain, percentage of SGR and FCR among the control and levamisole treated animals. Survival percentages of the animals treated with levamisole were better than the control.
Benedenia epinepheli (Yamaguti 1937), A Monogenean Parasite in Captive Broodstock of Grouper, Epinephelustauvina (Forskal)
Authors: JITHENDRAN K.P. , VIJAYAN K.K. , ALAVANDI S.V. , KAILASAM M.
Published: August 2021

Grouper (Epinephelus spp.) is one of the most economically important cultured marine fish in Asia, particularly in Thailand, Malaysia, Philippines, Singapore, Indonesia and Taiwan. Over 10 species of grouper fish have been cultured in the region. In India, greasy grouper fish, Epinephelus tauvina is gaining importance as a candidate species for marine and coastal aquaculture. A study conducted on wild and captive broodstock of grouper (size range, 15 - 40 cm; body weight 0.2 - 4 Kg) collected from sea near Chennai revealed infection with monogenean parasites in a large number of fishes (27%). The present communication is the summary of the prevalence, taxonomy and pathology of these infection encountered in E. tauvina and the containment strategies. Acute infection of ectoparasitic monogeneans, Benedenia sp. was observed in 19 wild grouper (E. tauvina) fish and 12 of the broodstock fish maintained in captivity. The parasite measured 2.05 - 3.29 x 0.66 - 1.33 mm and was found to infest the gills, fins and skin of the fish. Fishes with advanced infestation were characterized by erratic swimming behaviour and restlessness. The fish with severe infections had small focal haemorrhages on the body, which often resulted in secondary bacterial infection leading to the sloughing of the skin and excessive mucus secretion. A description of the parasite and its pathobiology is discussed. Successful treatment of monogenean infection was carried out by short bath treatment with 100 ppm formalin. Freshwater bath was found effective in dislodging the parasite from the fish. Hydrogen peroxide (150 ppm) bath was found to be effective but revival of parasite was observed after short bath.
Possibility of Using Latex Extracts of Nerium indicum Plant for Control of Predatory Fish Channa punctatus
Authors: TIWARI S. , SINGH A.
Published: August 2021

Laboratory evaluation was made to develop an environmentally safe and effective plant-origin piscicide. Piscicidal activity of different solvent extracts of Nerium indicum latex against the freshwater predatory snakehead, Channa punctatus was both time and dose-dependent, in terms of the lethal concentrations for 50% of the fish (LC50) always. Methanolic extract of N. indicum latex had LC50 of 17 mgL-1 at 24 h and 10 mgL-1 at 96 hour. Acetone, chloroform and diethyl ether extracts of N. indicum latex had LC50s of 18-23 mgL-1 at 24 h and 13-17 mgL-1 at 96 h. Exposure to sublethal doses (40% and 80% of LC50) of methanolic extract of N. indicum latex (which had maximum piscicidal activity) for 24 h or 96 h caused significant time and dose-dependent alterations in the concentrations of total protein, total free amino acid, nucleic acid, glycogen, pyruvate and lactate, and in the activity of the enzymes protease, alanine aminotransferase, aspartate aminotransferase, acid phosphates, alkaline phosphatase and acetylcholinesterase of snakehead. Thus, N. indicum latex shifts fish respiration towards the anaerobic pathway. The toxicity of the latex extract was reversible and 7 days after withdrawal, all biochemical parameters were back to normal. Thus, solvent extract of N. indicum latex can be used in aquatic environment for controlling unwanted populations of the snakehead Channa punctatus.
Explotación lobera en Tierra del Fuego:
Authors: Salerno Melisa , Zarankin Andrés , Cruz Jimena , Rigone Romina , Weissel Marcelo
Published: August 2021

Desde mediados del siglo XVIII, la explotación comercial de lobos marinos comenzó a transformarse en un negocio global. La naturaleza extractiva de las operaciones provocó que los cazadores expandieran continuamente su rango de acción. De este modo, desde finales del siglo XVIII, los loberos operaron activamente sobre diversas áreas del Atlántico Sur. La explotación comercial de lobos marinos en Tierra del Fuego alcanzó dimensiones importantes en el siglo XIX. A pesar de ello, los estudios efectuados hasta el momento resultan escasos. En este artículo describimos los primeros pasos de un proyecto que contempla estudiar sistemáticamente la actividad lobera en Tierra del Fuego desde la arqueología histórica. Por un lado, referimos al abordaje de documentos inéditos. Por el otro, consideramos el estudio de materiales históricos ya recolectados o excavados, y la planificación y ejecución de tareas de campo en un área acotada de la Isla Grande de Tierra del Fuego.
ANÁLISE EPIDEMIOLÓGICA DE CASOS DE HANSENÍASE EM UM MUNICÍPIO DO OESTE DO PARANÁ, NO PERÍODO DE 2013 A 2018
Authors: Kulevicz Murilo Sanches , Almeida Mello Tatiane De Fátima , Caporal Marcelo Rodrigo
Published: August 2021

Antigamente conhecida como Lepra, a Hanseníase possui como agente etiológico o Micobacterium leprae, sendo caracterizada pela OMS, como uma Doença Tropical Negligenciada. Com base na gravidade da doença e no problema de saúde pública que ela representa, esta pesquisa objetivou analisar o perfil epidemiológico dos casos de hanseníase no município de Cascavel-PR, no período de 2013 a 2018, através de dados do Sistema de Informação de Agravos de Notificação-SINAN. Trata-se de um estudo observacional, transversal, de abordagem quantitativa e de natureza descritiva, realizado mediante análise de fichas de notificação do SINAN.  Pode-se observar, no período estudado, a predominância de casos no sexo masculino em relação ao sexo feminino. A faixa etária que teve um número maior de casos, prevaleceu entre 35 a >60 anos; a classificação mais significativa foi a multibacilar e a forma clinica mais encontrada a dimorfa, com maior predomínio de casos na periferia do município. Diante das informações obtidas, pode-se concluir, que a realização de trabalhos dessa natureza é fundamental, pois possibilita transmitir conhecimentos fundamentais sobre a hanseníase, em vários aspectos epidemiológicos e clínicos, assim, contribuindo para a elaboração e/ou aprimoramento de políticas públicas para melhor assistência à saúde.
ADESÃO MEDICAMENTOSA DE PORTADORES DE HIPERTENSÃO ARTERIAL SISTEMICA EM UMA UNIDADE DE SAÚDE DA FAMÍLIA DE CASCAVEL- PR
Authors: Neder Elisa Neves , Tramontini Alexia Almeida , Moleta Brunno Mehret , Almeida Filipe Tomasi Keppen Sequeira de , Almeida Rui Manuel de Sousa Antunes
Published: August 2021

A Hipertensão Arterial Sistêmica (HAS) é um grave problema de saúde pública no Brasil e no mundo. A adesão ao tratamento medicamentoso entre pacientes com HAS é muito baixa, sendo ainda menor em países em desenvolvimento. Este estudo avaliou pacientes de uma Unidade de Saúde da família (USF), na cidade de Cascavel/PR, Brasil, já diagnosticados com HAS, avaliando a adesão ao tratamento em função das características demográficas dos mesmos. Para isso, foram entrevistados 200 pacientes através de questionários sociodemográfico e de adesão medicamentosa, os pacientes foram separados em grupos e suas respostas foram comparadas através do teste qui-quadrado de Pearson. Diversas questões não apresentaram diferença entre grupos separados por sexo, entretanto, verificou-se que houve diferença significativa quanto ao esquecimento em tomar a medicação, sendo que pacientes do sexo feminino alegaram esquecer mais frequentemente a medicação do que pacientes do sexo masculino. Quanto a faixa etária, verificou-se que pacientes mais jovens tem menor adesão ao tratamento medicamentoso, independente do sexo. Além disso pode-se constatar que o acesso gratuito ao medicamento e o relacionamento profissional-paciente são fatores importantes para a adesão ao tratamento medicamentoso de HAS.
ATIVIDADES ANTIOXIDANTE E ANTIMICROBIANA EM HIDROLISADOS DE PELE DE RÃ-TOURO
Authors: Da Silva Juliana Aparecida Mirante , Cunha Marina Brito , Justo Diego De Assunção , Nunes Ortência Leocádia Gonzalez da Silva , Cottica Solange Maria , Tiuman Tatiana Shioji
Published: August 2021

A indústria e a ciência estudam e desenvolvem produtos a partir de fonte natural para suprir a demanda por moléculas com atividades antioxidante e antimicrobiana. A pele de rã é um subproduto de frigoríficos de abate desse animal e tem sido objeto de estudo na prospecção de peptídeos bioativos oriundos de hidrólise enzimática. No Brasil, a rã-touro (Lithobates catesbeianus) é a única espécie permitida para exploração comercial em ranários para aproveitamento da carne. Este estudo teve por objetivo avaliar o uso do ultrassom em conjunto com a hidrólise enzimática de pele de rã-touro para a produção de peptídeos com atividades antioxidante e antimicrobiana. Os resultados mostraram que os peptídeos liberados pela hidrólise convencional da pele de rã-touro possuem expressiva atividade antioxidante. O uso de um sonicador diminuiu o tempo de hidrólise para 5 min, com a melhor potência de 250 W avaliada pelas análises do DPPH e do FRAP, enquanto que a potência de 100 W foi melhor para a análise do ABTS. Em relação à atividade antimicrobiana, os hidrolisados não apresentaram qualquer resultado na concentração de 20 mg mL-1, sendo necessário fazer outros estudos com valores maiores de concentração de amostra.
DOENÇAS ENDÓCRINAS DA SENESCÊNCIA: UMA REVISÃO DE LITERATURA
Authors: Da Silva Kiarah De Lima Tavares , Pescador Marise Vilas Boas
Published: August 2021

A diminuição da taxa de fecundidade, associada a diminuição da mortalidade e ao aumento na expectativa de vida, é um dos termos incumbidos pelo avanço no envelhecimento. Os números apresentados pelo Censo 2001 mostraram, para o nosso país, um aumento quantitativo das pessoas idosas. Um estudo específico das populações pelo método de estudo longitudinal terá de ser constituído por prioridades de centro de investigação aplicado, tendo em vista que a conta a pagar pelo aumento da expectativa de vida do ser humano tem progressivamente se tornado maior. É imprescindível escolher alvos para a atuação médica, para que consigamos deixar de ser apenas expectadores do processo de envelhecimento, e possamos diferenciar o que distingue ao longo da vida sucessos diferentes no envelhecimento. Diante disso, serão abordadas doenças endócrinas que, quando bem cuidadas durante a vida infantil e adulta, refletem em um envelhecimento saudável. O presente estudo tem como objetivo analisar o processo de envelhecimento relacionado às alterações morfológicas e fisiológicas que trazem implicações em diversos sistemas do organismo. A metodologia utilizada na análise dos dados da pesquisa foi de rastreio teórico, pois se valeu de revisão bibliográfica.
POSSÍVEL UTILIZAÇÃO DE CANABINOIDES NA DOENÇA DE ALZHEIMER: UMA REVISÃO
Authors: Linartevichi Vagner Fagnani , Cury Rafael De Morais , Nascimento Francisney Pinto
Published: August 2021

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Uso de contraste hepato-específico en fuga biliar secundaria a colecistectomía laparoscópica
Authors: Paz Juan , Kuestermann Sven
Published: August 2021

Una paciente de 23 años se presenta a la emergencia por distensión y dolor abdominal difuso asociado a vómitos, 4 días posteriores a colecistectomía laparoscópica debido a colecistitis aguda. El ultrasonido y la tomografía abdominal realizados de emergencia reportaron líquido libre intraabdominal. Se realizó resonancia magnética con contraste paramagnético hepato específico, ácido gadoxetico, que demuestra la acumulación del contraste en la fosa de la vesícula biliar 20 minutos después de su inyección. Se realizó ERCP para colocar prótesis biliar con el que se aísla la fuga de bilis.
I servizi offerti da una digital library
Authors: Segoni Dalila
Published: August 2021

Le digital library tendono sempre più a connotarsi non solo come ricche e variegate collezioni di risorse culturali ma come sistemi organizzati di servizi orientati agli utenti finali, percepiti non solo come consumatori di contenuti digitali ma anche come produttori attivi di contenuti. Piattaforme come Facebook e YouTube dimostrano che, quando i sistemi sono semplici da utilizzare e con finalità di interesse, gli utenti li utilizzano anche per contribuire con propri contenuti, quindi il loro coinvolgimento aumenta e la loro interazione diventa più attiva. In questa prospettiva, l'analisi che segue intende dimostrare come, nonostante qualche positivo esperimento, la strada per l'evoluzione delle digital library è quasi del tutto da esplorare. Partendo da un’analisi della natura e delle definizioni dei “servizi digitali”, sono state esaminate alcune importanti biblioteche digitali internazionali – Europeana Collections e la Digital Public Library of America – descrivendo le funzionalità e gli strumenti che mettono a disposizione degli utenti, al fine di definire una proposta di catalogo dei servizi necessari per lo sviluppo delle biblioteche digitali dedicate al patrimonio culturale.
Il progetto Biblioteca Digitale Leopardiana: per una catalogazione e digitalizzazione dei manoscritti autografi di Giacomo Leopardi
Authors: Melosi Laura , Marozzi Gioele
Published: August 2021

A seguito della digitalizzazione del Fondo Leopardiano della Biblioteca Nazionale di Napoli, avviata da tempo e appena giunta a conclusione, nel 2018 l’Università di Macerata ha promosso un analogo progetto relativo a tutti quei manoscritti che non essendo rimasti nella disponibilità di Antonio Ranieri alla morte del poeta, sono attualmente conservati in numerosi istituti italiani ed esteri. La ricognizione extra- napoletana intende ricostruire le dinamiche della confluenza delle carte leopardiane nelle collezioni che oggi le ospitano, evidenziando la necessità di procedere alla realizzazione di un catalogo unico per tutti i manoscritti di Leopardi e di creare uno strumento scientifico in grado non soltanto di dare conto della localizzazione di documenti di estrema importanza, ma anche di metterne a disposizione la riproduzione digitale e i metadati. Biblioteca Digitale Leopardiana sarà dunque un catalogo informatizzato dei manoscritti, arricchito dalle immagini acquisite direttamente sui documenti originali, che consentirà di visualizzare le singole schede e di verificarne le descrizioni. I dati, costantemente aggiornabili e valorizzabili, agevoleranno gli studi leopardiani e saranno fruibili, almeno in una fase iniziale, attraverso due canali ufficiali dell’ICCU, ManusOnLine e InternetCulturale, da cui sarà possibile esportare il tracciato dei metadati in formato XML a garanzia della conservazione a lungo termine e dell’interoperabilità con altri sistemi.
Un caso di applicazione dello standard MAG: le digitalizzazioni da microfilm di strumenti di corredo storici
Authors: Delneri Francesca
Published: August 2021

Lo standard Metadati Amministrativi e Gestionali (MAG) può trovare applicazione nel caso delle riproduzioni digitali realizzate a partire da microfilm, in particolare per gli strumenti di corredo coevi alla documentazione. I vantaggi consistono nella possibilità di assemblare file MAG diversi, corrispondenti a supporti diversi, per ricostituire l’unità archivistica riprodotta su microfilm, e di utilizzare la sezione  per restituire le partizioni interne di repertori, rubriche e indici. Si fornisce un esempio di applicazione dello standard al repertorio dei contraenti degli atti notarili denominato “Indice Masini” (secc. XIV-XVII).
Design of In-phase and Quadrature Two Paths Space-Time-Modulated Metasurfaces
Authors: Li Mengmeng , Li Mengmeng , Bilotti Filiberto
Published: August 2021

Space-time-modulated metasurfaces can manipulate electromagnetic waves
in space and frequency domain simultaneously. In this paper, an analytical design
of space-time- modulated metasurfaces with modulation elements composed of two
paths, In-phase (I) and Quadrature (Q), is proposed. The model is derived analytically,
the space/frequency domain manipulations are achieved
by designing the dimension and time sequence of I and Q paths. In the specular reflection direction, an objective frequency
shift of the reflected first order harmonic can be obtained. While, in other
directions, the opposite first order harmonic can be easily controlled by
changing the dimension of I/Q paths and the objective first order harmonic
remains unchanged. Furthermore, with a small dimension of I/Q paths, the
first order harmonic can be used for beam scanning by pre-designing the start
time of the modulation element. To realize the space-time-modulated metasurface
with the required periodically time-varying responses, 2-bit unit-cells loaded
with dynamically switchable pin diodes are employed as I/Q modulation. Both
analytical and numerical results demonstrate that space and frequency domain
manipulations of the reflected fields by the first order harmonics can be
simultaneously obtained. The proposed designs have potential applications in
wireless communications, radar camouflaging, and cloaking.
AllelePred: A Simple Allele Frequencies Ensemble Predictor for Different Single Nucleotide Variants
Authors: Sobahy Turki , Alazmi Meshari
Published: August 2021

Genomic medicine stands to be revolutionized through the understanding of single nucleotide variants (SNVs) and their expression in single-gene disorders (mendelian diseases). Computational tools can play a vital role in the exploration of such variations and their pathogenicity. Consequently, we developed the ensemble prediction tool AllelePred to identify deleterious SNVs and disease causative genes. In comparison to other tools, our classifier achieves higher accuracy, precision, F1 score, and coverage for different types of coding variants. Furthermore, this research analyzes and structures 168,945 broad spectrum genetic variants from the genomes of the Saudi population to denote the accuracy of the model. When compared, AllelePred was able to structure the unlabeled Saudi genetic variants of the dataset to mimic the data characteristics of the known labeled data. On this basis, we accumulated a list of highly probable deleterious variants that we recommend for further experimental validation prior to medical diagnostic usage.
Microbial synthesis and evaluation of bactericidal properties of cadmium sulfide nanoparticles
Authors: Zhuravliova O. A. , Voeikova T. A. , Kuligin V. S. , Debabov V. G.
Published: August 2021

Introduction. The productivity of microbial synthesis of stable nanoparticles is determined by the growth stage of the populations of bacterial cultures used to obtain nanostructures. The study of the biocidal activity of biogenic nanoparticles of cadmium sulfide (NPsCdS), comparable in properties with nanomaterials obtained by physicochemical methods, is promising.The aim of this work was to evaluate the effect of the cell growth phase of the bacterial strains Bacillus subtilis 168 and Shewanella oneidensis MR-1 on the efficiency of biosynthesis of NPsCdS and to study their bactericidal properties against a number of gram-positive and gram-negative strains of microorganisms.Material and methods. Nanoparticles were obtained by introducing Na2S and CdCl2 salts to a final concentration of 2 mM : 2 mM in liquid bacterial cultures with cells in different phases of growth. The efficiency of NPsCdS biosynthesis was evaluated by the optical density of aqueous nanoparticles solutions. The bactericidal properties of NPsCdS were determined by the diameter of zone of inhibition growth of gram-positive bacteria B. subtilis 168, B. amyloliquefaciens, Streptococcus salivarius, Rhodococcus rhodochrous and gram-negative S. oneidensis MR-1, Escherichia coli K-12, Pseudomonas putida.Results. It was found that the use of cells in the stationary phase of growth (18–24 hours) contributes to obtaining the maximum amount of NPsCdS corresponding to concentrations of 1.0–1.2 mg/ml. The high antimicrobial activity of NPsCdS was shown against gram-positive microorganisms, among gram-negative bacteria, P. putida strain showed insignificant sensitivity.Discussion. The experimental results expand scientific data about the effect of the phase of bacterial growth cycle on biosynthesis of nanoparticles. The stationary phase of growth of B. subtilis 168, S. oneidensis MR-1 is optimal for obtaining of NPsCdS. For the first time, the cytotoxicity of NPsCdS/Shewanella against bacteria of various taxonomic groups was demonstrated.Conclusion. An effective method for obtaining extracellular NPsCdS using bacteria B. subtilis 168, S. oneidensis MR-1 in the stationary phase of growth has been developed. The biocidal activity of biogenic NPsCdS was shown, which allows to consider them as a new class of antimicrobial agents.
EBUS-TBNA versus surgical mediastinoscopy for mediastinal lymph node staging in potentially operable non-small cell lung cancer: a systematic review and meta-analysis
Authors: Rossi Figueiredo1,2 Viviane , Francisco Guerreiro Cardoso3a Paulo , Jacomelli2 Marcia , Maia Santos4 Lilia , Minata5 Mauricio , Mingarini Terra1,3 Ricardo
Published: August 2021

Artigo: EBUS-TBNA versus mediastinoscopia cirúrgica no estadiamento linfonodal mediastinal do câncer de pulmão de células não pequenas potencialmente operável: revisão sistemática e meta-análise

Publicação: J Bras Pneumol. 2020;46(6):e20190221

DOI: https://dx.doi.org/10.36416/1806-3756/e20190221

Na página 6 da publicação original, na Figura 2, onde se lia:
Time course of exercise capacity in patients recovering from COVID-19-associated pneumonia
Authors: Zampogna1 Elisabetta , Ambrosino2 Nicolino , Saderi3 Laura , Sotgiu3 Giovanni , Bottini4 Paola , Pignatti5 Patrizia , Centis6 Rosella , Battista Migliori6 Giovanni , Spanevello1,4 Antonio , Zappa4 Martina , isca1,4 Dina V
Published: August 2021

Objective: High prevalences of muscle weakness and impaired physical performance in hospitalized patients recovering from COVID-19-associated pneumonia have been reported. Our objective was to determine whether the level of exercise capacity after discharge would affect long-term functional outcomes in these patients. Methods: From three to five weeks after discharge from acute care hospitals (T0), patients underwent a six-minute walk test (6MWT) and were divided into two groups according to the distance walked in percentage of predicted values: <75% group and =75% group. At T0 and three months later (T1), patients completed the Short Physical Performance Battery and the Euro Quality of Life Visual Analogue Scale, and pulmonary function and respiratory muscle function were assessed. In addition, a repeat 6MWT was also performed at T1. Results: At T0, 6MWD values and Short Physical Performance Battery scores were lower in the <75% group than in the =75% group. No differences were found in the Euro Quality of Life Visual Analogue Scale scores, pulmonary function variables, respiratory muscle function variables, length of hospital stay, or previous treatment. At T1, both groups improved their exercise capacity, but only the subjects in the <75% group showed significant improvements in dyspnea and lower extremity function. Exercise capacity and functional status values returned to predicted values in all of the patients in both groups. Conclusions: Four weeks after discharge, COVID-19 survivors with exercise limitation showed no significant differences in physiological or clinical characteristics or in perceived health status when compared with patients without exercise limitation. Three months later, those patients recovered their exercise capacity.
Música colombiana en batería. Lenguajes contemporáneos
Authors: Hernández Martínez Manuel Antonio
Published: August 2021

El documento “La batería en la música colombiana”, tiene como fin primordial el de constituirse en un material de trabajo, consulta y enseñanza/aprendizaje para los estudiantes del programa de pregrado en música; este tipo de materiales, en contraste con lo encontrado sobre músicas de Brasil, Argentina, Cuba o Estados Unidos, es un vacío importante que este material ayuda a llenar, aportando información teórica y metodológica para estudiantes de pregrado alrededor de las músicas tradicionales y regionales del Colombia; teniendo en cuenta que además el texto aborda todas las zonas geográficas del país. El libro viene acompañado con un material de audio que acompaña el texto musical, por medio de cual se complemente el estudio de las músicas presentadas. En el formato tradicional se propone publicar este material como un libro acompañado por un CD o en su defecto como un libro electrónico con los audios conectados al material.
Implementation of Community Service in The Introduction of History in the Sembulungan Peninsula, Banyuwangi Regency, East Java Province Indonesia
Authors: Mursidi Agus , Tofan Priananda Adinata  , Abdul Shomad  , Dhalia Soetopo  , Miskawi  , Atim Hariadi
Published: August 2021

One of the relics whose existence must be preserved and preserved is in Banyuwangi Regency, precisely in Alas Purwo National Park (TN Alas Purwo), a national park located in Banyuwangi covering an area of 43,420 hectares. In addition to having a diversity of flora and fauna in the Alas Purwo National Park area, there are also many objects and buildings of the past, especially on the Sembulungan peninsula, which was formerly known as an entry and exit route for colonial trade commodities. However, let alone the student community who are academics who are not very familiar with the relics on the Sembulungan peninsula, the method used in this service is qualitative analysis by coming to the location directly and conducting observations and collecting data through structured interviews with a triangulation approach. The results show that students' insight has increased by looking at the relics of the Japanese military in maintaining power in the form of bunkers, cannons, and military strategies developed on the Sembulungan peninsula for maritime security.
Training on the Utilization of Household Organic Waste as Compost Fertilizer in Tamansuruh Village
Authors: Jefry Aulia Martha  , Mohammad Hilfi Azra Dzikrulloh  , Reta Lola Oftaviana  , Hafifatus Syabila
Published: August 2021

Problems related to waste, waste processing, to environmental pollution will become a big problem if not handled properly. These problems can be solved with economical solutions such as the utilization of household organic waste into compost. This program aims to help the community to be able to produce compost from household organic waste in Tamansuruh Village, which is one of the villages in Glagah District, Banyuwangi Regency. Where the problems faced by the villagers are the lack of information and limited knowledge about new innovations in making compost. The process used in this composting is anaerobically assisted by a simple composter. To achieve this goal, the method used is preparation in the form of observation of problems, implementation in the form of socialization, training, and direct practice, and evaluation. The result of this activity is in the form of compost derived from household organic waste made by residents and for the residents themselves. Making compost is also able to increase the innovation power of residents in managing household organic waste and increase productivity in the field of agriculture.
Effect of modification on impact strength of critical carriage castings made of 20GL steel
Authors: Bogdanov R.A.
Published: August 2021

Effect of modifiers on the basis of rare-earth and alkali-earth metals on microstructure and impact toughness of car castings made of low-alloy casting 20GL steel of open-hearth and electroarc melts on the basis of statistical and microstructural analysis is considered. The relationship between the steel impact toughness level, matrix grain parameters and non-metallic inclusions is studied.
Preform design in axial hot closed die forging by isothermal surface method. Part 3. Preform design of industrial cases
Authors: Vlasov A.V. , Krivenko D.V. , Stebunov S.A. , Biba N.V. , Dyuzhev A.M.
Published: August 2021

The isothermal surfaces method for preform design is proposed. The procedure for determining of the preform shape is given. The features in using of the method for forgings with various shapes are considered. The method is illustrated by industrial examples. The design algorithm uses the QForm metal forming simulation software to build isothermal surfaces and check the quality of the designed die geometry by finite element modeling, as well as specially developed version of the QFormDirect CAD based on SpaceClaimтм.
Prospects for use of laser processing equipment in metalworking
Authors: Veremeevich A.N. , Gorbatyuk S.M. , Zharikov V.M. , Nagovitsyn V.A.
Published: August 2021

The arguments for widespread use of the new class of fibre laser in the design of the technological equipment and introduction of laser technologies in production are given. The technological possibilities of these laser are demonstrated.
ʻAlāqah al-Khalfiyyat at-Taʻlīmiyyah al-Lugah al-ʻArabiyyah ʻalā Mahārah al-Qirā’ah
Authors: Solehuddin Solehuddin , Setiabudi Muhammad Arif
Published: August 2021

Arabic language education background has an important relationship with students' reading skills, however the situation in each place of learning is different, where public schools do not teach Arabic, while Islamic religious-based schools are the opposite. This article aimed to find 1) the educational background of students; 2) students' reading skills; and 3) the relationship between educational background and reading skills. Researchers used quantitative methods with the research subjects of seventh grade students of MTs Salafiyah Syafi'iyah Seblak Jombang. The results of the research showed 1) the educational background of the percentage of students who voted strongly agree 40%, 43% agree, 15% disagree, and 2% strongly disagree; 2) the students' ability to read Arabic at a very good level of 53.57%, good 33.92%, and not good 14.28%; and 3) there were a relationship between educational background and reading ability of students based on the value of Sig2 tailed = 0.466 which is greater than 0.05. This shows that Islamic religious-based schools encourage students to have Arabic reading skills.