bluuebunny/crossref_metadata_2025 huggingface dataset:
Die frühesten türkischen Übersetzungen von Tausendundeiner Nacht und deren Bedeutung für die arabische Textgeschichte
Authors: Thomann Johannes
Published: March 2016

Despite the shoreless output of scholarly publications on the Thousand and One Nights in general, research on the textual history is comparatively limited. Given the small number of early Arabic manuscripts, evidence from early translations is crucial for any reconstruction of the Mamluk version of the Thousand and One Nights, written approximately between 1425 and 1500 CE. For some time, the existence of an early Turkish translation, extant in two manuscripts and dated to the fifteenth century CE on linguistic grounds, has been known. The two manuscripts cover the first 56 nights of the work. A later Turkish version, written in the seventeenth century CE, extant in a nine volume manuscript, has been known for a long time too. In this contribution, the discovery of further parts of the oldest Turkish translation is indicated for the first time. Text samples are edited, translated and compared to the oldest Arabic version of the Thousand and One Nights. A collation with the nine volume manuscript has shown that parts of it contain the earlier translation of the fifteenth century. Furthermore, some Turkish versions of single stories also belonging to the Thousand and One Nights are discussed. Among these are the story of the Queen of the serpents (Cāmaspnāme) and the story of Sayf al-Mulūk. Based on the new evidence from Turkish manuscripts and their numbering of the nights, an overall view on the puzzle of fragments is given. The same is done for the early Arabic manuscripts. As a result, it has turned out that both groups show the same sequence of stories. There are inserted stories, but no reversed order of stories is found. This suggests that a stable tradition of the overall structure of the work existed. Finally, the contribution contains an inventory of 62 Turkish manuscripts of the Thousand and One Nights and of single stories.
An Interpretation of the Relationship between Chan-Buddhism and the State with Reference to the Monastic Code at the End of the Yuan Era
Authors: Fritz Claudia
Published: March 2016

Based on the monastic code entitled Chixiu Baizhang qinggui (Imperial Edition of Baizhang’s Rule of Purity), this article discusses the relations between Chan-monasteries and the state during the Yuan dynasty. The first chapter shows the state’s attitude towards religion and the ranking of the different Buddhist schools as well as the liturgical ceremonies for the emperor and the State and their rewards in form of financial and land donations. The second chapter explores to what extent the state’s veto in the elections of an abbot, its financial restrictions, and limited edition of ordination certificates could have been part of a repressive policy towards Buddhism. Conclusively, the inability of the monastic management to cope with their increased social and financial responsibilities impaired the Essential Teaching and further development of Chan-Buddhism.
Fliehende Objekte: Rey Chows Beiträge zur postkolonialen Theorie
Authors: Riemenschnitter Andrea
Published: March 2016

Based on her sharp, cutting-edge analyses of a wide range of theoretical and aesthetic texts, Rey Chow deconstructs the ideological surface of the world’s configuration of political power structures and social processes under the global neoliberal capitalist world order. In particular, her attention is directed to the objects of aesthetic reflection, which according to her reside both within and beyond the film, literary text, or work of art. Lost, found or fleeting, these objects ground human consciousness and are a major constitutive of cultural memory, knowledge production, and creativity. Her work includes analyses of the interventions of postcolonial intellectuals, who after decades of anticolonial struggles still find themselves confronted with the West’s colonial-imperialist attitudes, policies and poetics. Studying the objects of postcolonial world-making, Chow concentrates on the peripheries and contact zones, where ethnic inequalities cannot fully be hidden underneath glossy transcultural fassades. In order to shed light on the unintended side effects of western universalizing theories, she scrutinizes the displaced meanings of widely used concepts such as language, translation, mimesis, melancholy, visuality, or entanglement when applied in postcolonial aesthetic contexts. New meanings are unearthed from modernist, post-colonial, post-structuralist and other theories when shifted onto the plane of alternative models of worlding and community formation in sinophone writers’ and film directors’ works.
Thermodynamic effects after Diode and Er:YAG laser irradiation of grade IV and V titanium implants placed in bone – an ex vivo study. Preliminary report
Authors: Matys Jacek , Botzenhart Ute , Gedrange Tomasz , Dominiak Marzena
Published: March 2016

Many inserted implants are affected by peri-implantitis. The aim of our study was to evaluate increases in implant temperature, depending on the diameter and chemical composition of implants. In particular we measured the time it takes for the temperature of an implant to rise by 10°C and evaluated laser power settings required to prevent thermal injury when an implant surface is decontaminated during the treatment of peri-implantitis. The study analysed six implants placed in porcine ribs and divided into two groups according to their diameter and chemical composition (grade IV and grade V titanium). The implants were irradiated with Diode and Er:YAG lasers using different laser parameters. The temperature was measured with a K-type thermocouple. The temperature on the implant surface rose as the laser power increased and the implant diameter decreased. The time required to increase the temperature of an implant by 10°C was less than it was for titanium grade IV. The temperature gradient was below 10°C for all implants treated using a laser power up to 1 W. It is important to choose the correct laser parameters, depending on the chemical composition and diameter of the implant, so that decontamination of the implant surface is thorough, effective and safe.
Thoracoschisis secondary to a mesenchymal hamartoma associated with diaphragmatic eventration
Authors: Travers Colm P. , Hamm Jared Austin , Cleveland Sue , Chen Mike K. , Anderson Scott , Philips Joseph B.
Published: March 2016

Thoracoschisis is an extremely rare congenital anomaly associated with limb body wall defect and diaphragmatic hernia. We describe a case of a female infant who was noted at birth to have tissue coming through a left sided thoracic defect next to an accessory nipple. The stomach bubble was displaced superiorly on radiographs. At surgery the tissue was attached to the left lateral lobe of the liver and was protruding through the chest wall via an intercostal defect below an eventrated diaphragm. The tissue was resected and the defect closed. Pathological examination was consistent with a mesenchymal hamartoma. The diaphragm may have formed abnormally in this case due to the presence of the mesenchymal hamartoma in this location.
On the boundedness of a B-Riesz potential in the generalized weighted B-Morrey spaces
Authors: Ayazoglu (Mashiyev) Rabil , Hasanov Javanshir J.
Published: March 2016

We consider the generalized shift operator associated with the
Laplace–Bessel differential operator

Δ
B

=

∑

i
=
1

n

∂
2

∂

x
i
2

+

∑

i
=
1

k

γ
i

x
i

∂

∂

x
i

.

$
\Delta _{B}=\sum _{i=1}^{n}\frac{\partial ^2 }{\partial x_i^2} +\sum _{i=1}^{k} \frac{\gamma _i }{x_i}\frac{\partial }{\partial x_i}.
$

The maximal operator

M
γ

${M_{\gamma }}$

(B-maximal operator) and the Riesz potential

I

α
,
γ

${I_{\alpha ,\gamma }}$

(B-Riesz potential), associated with the generalized shift operator are investigated.
We prove that the B-maximal operator

M
γ

${M_{\gamma }}$

and the B-singular integral operator are bounded from the generalized weighted B-Morrey space

ℳ

p
,

ω
1

,
φ
,
γ

(

ℝ

k
,
+

n

)

${{\cal M}_{p,\omega _1,\varphi ,\gamma }(\mathbb {R}_{k,+}^{n})}$

to

ℳ

p
,

ω
2

,
φ
,
γ

(

ℝ

k
,
+

n

)

${{\cal M}_{p,\omega _2,\varphi ,\gamma }(\mathbb {R}_{k,+}^{n})}$

for all

1
<
p
<
∞

${1 < p < \infty }$

,

φ
∈

A

p
,
γ

(

ℝ

k
,
+

n

)

${\varphi \in A_{p,\gamma }(\mathbb {R}_{k,+}^{n})}$

.
Furthermore, we prove that the B-Riesz potential

I

α
,
γ

${I_{\alpha ,\gamma }}$

,

0
<
α
<
n
+
|
γ
|

${0<\alpha <n+|\gamma |}$

, is bounded from the generalized weighted B-Morrey space

ℳ

p
,

ω
1

,
φ
,
γ

(

ℝ

k
,
+

n

)

${{\cal M}_{p,\omega _1,\varphi ,\gamma }(\mathbb {R}_{k,+}^{n})}$

to

ℳ

q
,

ω
2

,
φ
,
γ

(

ℝ

k
,
+

n

)

${{\cal M}_{q,\omega _2,\varphi ,\gamma }(\mathbb {R}_{k,+}^{n})}$

, where

α
/

(
n
+
|
γ
|
)

=
1
/
p
-
1
/
q

${{\alpha }/{(n+|\gamma |)}=1/p-1/q}$

,

1
<
p
<
(
n
+
|
γ
|
)
/
α

${1<p<(n+|\gamma |)/{\alpha }}$

,

φ
∈

A

1
+

q
/

p
'

,
γ

(

ℝ

k
,
+

n

)

${\varphi \in A_{1+{q/p^{\prime }},\gamma }(\mathbb {R}_{k,+}^{n})}$

and

1
/
p

+

1
/

p
'

=
1

${{1/p}+{1/p^{\prime }}=1}$

.
Some explicit expressions concerning BP
Authors: Bakuradze Malkhaz , Jibladze Mamuka
Published: March 2016

This paper provides some explicit expressions concerning the formal group laws of the following cohomology theories: BP, the Brown–Peterson cohomology, G(s), the cohomology theory obtained from BP by putting

v
i

=
0

${v_i=0}$

for all i ≥ 1 with

i
≠
s

${i \ne s}$

, the Morava K-theory and the Abel cohomology.
The coefficient rings of Weierstrass universal elliptic curve formal group law are computed in low dimensions.
RE
2B8O15 (RE = La, Pr, Nd) – syntheses of three new rare earth borates isotypic to Ce2B8O15
Authors: Glätzle Matthias , Hoerder Gregor J. , Huppertz Hubert
Published: March 2016

The rare earth borates RE
2B8O15 (RE = La, Pr, Nd) were synthesized in a Walker-type multianvil apparatus under conditions of 5.5 GPa and 1100 °C. Starting from the corresponding rare earth oxides and boron oxide, the syntheses yielded crystalline products of all new compounds that allowed crystal structure analyses based on single-crystal X-ray diffraction data for La2B8O15 and Nd2B8O15. The compound Pr2B8O15 could be characterized via X-ray powder diffractometry. The results show that the new compounds crystallize isotypically to Ce2B8O15 in the monoclinic space group P2/c. The infrared spectra of RE
2B8O15 (RE = La, Pr, Nd) have also been studied.
Theologians, War, and the Universities: Early English interpretations of the “Manifesto of the Ninety-Three”, 1914–15
Authors: Inman Daniel D.
Published: March 2016

From von Harnack’s speech-writing for Kaiser Wilhelm II to the ‘Manifesto of the Ninety-Three’, theologians played an important role in justifying the defence of Kultur in the early stages of the First World War. This paper uses the war-pamphlet collection of William Sanday in the library of The Queen’s College to explore how English - and particularly Oxford - theologians responded to, and publically justified, British involvement in the war. Asserting that Oxford theologians were hesitantly nationalist by comparison with their German colleagues, this paper suggests that this dissimilarity cannot be explained purely by reference to the intellectual - some said, Nietzschean - arrogance of German theological liberals. Rather, the more cautious relationship of theologians in Britain to political and wider ecclesiastical discourse can, to some degree, be viewed through the lens of significant institutional differences between German and British theological faculties at the outbreak of the war.
Information literacy of the academic library users
Authors: Hasenay Sanda , Šuvak-Pirić Ivana , Mokriš Svjetlana , Horvat Ines
Published: March 2016

Information literacy should be a foundation of any educational system, which would enable students and library users a more efficient way to perform academically and in everyday life. The research goal was to determine the level of information literacy among the students, users of the Library of Faculty of Food and Technology Osijek (PTFOS). A special survey – quiz was used to determine students’ knowledge of library collection and services. The sample of 115 students was surveyed between 16th and 27th of February 2015. The library users are aware of the conditions of using the library collections as well as library services, but they don't read messages on the library's bulletin board, desks and web site. The research results will be used as guidelines for improving information literacy and future research.
Glandular epithelial AR inactivation enhances PTEN deletion-induced uterine pathology
Authors: Choi Jaesung (Peter) , Zheng Yu , Handelsman David J , Simanainen Ulla
Published: March 2016

Phosphatase and tensin homolog (PTEN) deletion induces uterine pathology, whereas androgen actions via androgen receptor (AR) support uterine growth and therefore may modify uterine cancer risk. We hypothesized that the androgen actions mediated via uterine glandular epithelial AR could modify PTEN deletion-induced uterine pathology. To test our hypothesis, we developed uterine glandular epithelium-specific PTEN and/or AR knockout mouse models comparing the uterine pathology among wild-type (WT), glandular epithelium-specific AR inactivation (ugeARKO), PTEN deletion (ugePTENKO), and the combined PTEN and AR knockout (ugePTENARKO) female mice. The double knockout restricted to glandular epithelium showed that AR inactivation enhanced PTEN deletion-induced uterine pathology with development of intraepithelial neoplasia by 20 weeks of age. In ugePTENARKO, 6/10 (60%) developed intraepithelial neoplasia, whereas 3/10 (30%) developed only glandular hyperplasia in ugePTENKO uterus. No uterine pathology was observed in WT (n=8) and ugeARKO (n=7) uteri. Uterine weight was significantly (P=0.002) increased in ugePTENARKO (374±97 mg (mean±s.e.)) compared with WT (97±6 mg), ugeARKO (94±12 mg), and ugePTENKO (205±33 mg). Estrogen receptor alpha (ERα) and P-AKT expression was modified by uterine pathology but did not differ between ugePTENKO and ugePTENARKO, suggesting that its expressions are not directly affected by androgens. However, progesterone receptor (PR) expression was reduced in ugePTENARKO compared to ugePTENKO uterus, suggesting that PR expression could be regulated by glandular epithelial AR inactivation. In conclusion, glandular epithelial AR inactivation (with persistent stromal AR action) enhanced PTEN deletion-induced uterine pathology possibly by downregulating PR expression in the uterus.
A Pathway Analysis of Melanin Patterning in a Hemimetabolous Insect
Authors: Liu Jin , Lemonds Thomas R , Marden James H , Popadić Aleksandar
Published: March 2016

Diversity in insect pigmentation, encompassing a wide range of colors and spatial patterns, is among the most noticeable features distinguishing species, individuals, and body regions within individuals. In holometabolous species, a significant portion of such diversity can be attributed to the melanin synthesis genes, but this has not been formally assessed in more basal insect lineages. Here we provide a comprehensive analysis of how a set of melanin genes (ebony, black, aaNAT, yellow, and tan) contributes to the pigmentation pattern in a hemipteran, Oncopeltus fasciatus. For all five genes, RNA interference depletion caused alteration of black patterning in a region-specific fashion. Furthermore, the presence of distinct nonblack regions in forewings and hindwings coincides with the expression of ebony and aaNAT in these appendages. These findings suggest that the region-specific phenotypes arise from regional employment of various combinations of the melanin genes. Based on this insight, we suggest that melanin genes are used in two distinct ways: a “painting” mode, using predominantly melanin-promoting factors in areas that generally lack black coloration, and, alternatively, an “erasing” mode, using mainly melanin-suppressing factors in regions where black is the dominant pigment. Different combinations of these strategies may account for the vast diversity of melanin patterns observed in insects.
A Narrative Approach to Both Teaching and Learning About Democracy with Young Children: A Theoretical Exploration
Authors: Rahim Maila Dinia husni , Rahim Husni
Published: March 2016

As adults, we often believe that children are only interested with games and children’s ‘stuff’. However research has shown that children do indeed show a greater interest in the world around them, including about politics, elections, and democracy. If we need to teach children about democracy, what are the best methods of teaching democracy to young children? Narrative is considered as an effective medium to convey messages to children and discuss hard subjects. This paper is a theoretical exploration that looks at the narrative approach to teaching and learning about democracy with young children. The researchers has used a literature review to look at why narratives should be used, what narratives should be used and how to use narratives.
Youth-Adult Partnership: A New Way Forward for Greater Muslim Youth Participation in Schools and Communities
Authors: Krauss Steven Eric
Published: March 2016

Young people in Muslim majority countries are a valuable asset and investing in them can bring tremendous social and economic benefits. They also face many challenges that undermine their ability to develop and contribute to society. To make the most of the opportunity, these countries must find ways to increase the human and social capital of their respective youth populations. Youth participation in formal and non-formal educational settings such as schools and community programs has been identified as an effective approach to enhancing young people’s experiences. Building on initial findings from Malaysia, the current paper puts forth the concept of youth-adult partnership (Y-AP) as a strategy for schools. Y-AP has been shown to enhance personal agency, empowerment and connection to community, three attributes that are critical for Muslim youth to play more substantive roles in national development. The paper further attempts to frame Y-AP within an Islamic socio-historical lens, drawing on examples from the Prophet Muhammad SAW and the early Muslim community to show how developmental relationships were central to the social and educational culture within the Prophet’s community. Permalink/DOI: http://dx.doi.org/10.15408/sd.v2i2.2810
Sejaran dan Prospek Demokrasi
Authors: Supardan Dadang
Published: March 2016

This article was written for the anxiety of the phenomenon of the rise of the idea of ​​democracy as if change is to be erratic form of government, not driven by reason and rational needs. That since its inception, the idea of ​​democracy increasingly widespread after experiencing various historical events, especially when the formulation of the American Constitution in 1776 and the French Revolution of 1789. The democratic system is becoming more popular among followers of republicanism and is a critique of the dominance of the monarchy system in Europe. Nowadays, democracy can be seen as a ‘product’ as that term is defined previously as a ‘source of power’ rather than as ‘a method of governance’. Despite modern democracy is a complex device, but logic is expressed seem to contain a single principles. That democracy contains elements of popular participation, majority rule, minority protection, individual freedom, freedom guaranteed by law, participation in policy formulation at all levels, as well as equality. However, democracy is not without flaws, both conceptually mapun practice, given the many democracies that do not accommodate the interests of the sovereignty of the environment (ecocracy). Permalink/DOI: http://dx.doi.org/10.15408/sd.v2i2.2811
Telaah Teoritis: Internalisasi Nilai-Nilai Demokrasi dalam Budaya Sekolah
Authors: Hapsari Sri
Published: March 2016

This article provides an theoretical overview of the internalization of democratic values in the school culture. The concept of democratic values in school culture obtained through study of literature. Democratic values considered important for the student as early as possible. Through the school culture, democratic values will be effectively internalized. These value aren’t theoretical, but the values of democratic is implemented in the life of the school with school culture. School culture is interpreted as the norm; value; school rules that are binding on the entire school community. Democratic values that can be applied at schools such as transparency, resolve the issue peacefully, regularly class elections management, acknowledging the diversity in the schools, and so on. Permalink/DOI: http://dx.doi.org/10.15408/sd.v2i2.2813
POLITIK PENYEDERHANAAN SISTEM KEPARTAIAN DI INDONESIA PASCA REFORMASI 1998
Authors: Sutisna Agus
Published: March 2016

Since the 1999 elections electoral democracy Indonesia is marked by drastic changes in the party system implementation, from simple multi-party system in the New Order era to the extreme multiparty system. Judging from the election as the most massive space is provided to facilitate the political participation of the people, multiparty phenomenon is certainly a sign that democracy was growing. But in terms of the need to realize the importance of a stable and effective government, multiparty phenomenon is actually not a wise choice. Scott Mainwaring comparison study results conclude that the application of a multi-party system with a presidential system is a bad combination. That is why since the 2004 elections simplification efforts of party system in Indonesia is done through various policy strategy. This paper is a study about the application of extreme multiparty system and its impact on the election, the behavior of political parties in Parliament, and the relation of Parliament-President; and political strategy or policy simplification of party system that has been taken in Indonesia after the reform to realize a simple multiparty system. Permalink/DOI: http://dx.doi.org/10.15408/sd.v2i2.2816
Demokrasi Ersatz: Menggugat Peran Pemuda dalam Mengawal Proses Demokratisasi di Indonesia
Authors: Iqbal Mahathir Muhammad
Published: March 2016

We already are in an open democratic stage within 17 years . However , we are also required to continue to make serious resolutions and improvements related to the character of the ideology of democracy . In many ways , we still fail to open up possibilities and alternatives in managing circulation prospective leadership and in accordance with the requirements of democracy . Fundamental changes to equip democracy needs to be done for the sake of the birth of the benefit shared values ​​. In this context, youth should play a role . youth should proofread and guarding the democratic process in order not to handcuffed by pragmatic political interests . Moreover, if we depart from the conviction , that the youth are the leaders of future generations. Permalink/DOI: http://dx.doi.org/10.15408/sd.v2i2.2817
Neurodevelopmental Outcomes Following Bevacizumab Injections for Retinopathy of Prematurity
Authors: Morin Julie , Luu Thuy Mai , Superstein Rosanne , Ospina Luis H. , Lefebvre Francine , Simard Marie-Noëlle , Shah Vibhuti , Shah Prakesh S. , Kelly Edmond N. ,   the Canadian Neonatal Network and the Canadian Neonatal Follow-Up Network Investigators
Published: March 2016

BACKGROUND AND OBJECTIVE:

Bevacizumab intravitreal injection, a vascular endothelial growth factor inhibitor, is used to treat retinopathy of prematurity (ROP). However, concerns have been raised regarding its systemic absorption and effect on developing tissues including brain. This study compared neurodevelopment at 18 months’ corrected age in preterm infants of <29 weeks’ gestation treated with bevacizumab versus laser ablation.

METHODS:

Data from the Canadian Neonatal Network and the Canadian Neonatal Follow-Up Network databases were retrospectively reviewed. Infants born at <29 weeks’ in 2010–2011 with treated ROP were studied. Neurodevelopmental outcome at 18 months was assessed by using neurologic examination and the Bayley Scales of Infant and Toddler Development Third Edition. Regression analyses were performed.

RESULTS:

Of 125 treated infants, 27 received bevacizumab and 98 laser. The bevacizumab group, compared with laser, obtained a median Bayley Scales of Infant and Toddler Development Third Edition motor composite score of 81 (interquartile range, 70–91) versus 88 (79–97), a language composite score of 79 (65–97) versus 89 (74–97), and a cognitive score of 90 (80–100) versus 90 (85–100). Difference was detected on the motor score only (P = .02). Odds of severe neurodevelopmental disabilities (Bayley scores <70, severe cerebral palsy, hearing aids, or bilateral blindness) was 3.1 times higher (95% confidence interval: 1.2–8.4) in infants treated with bevacizumab versus laser after adjusting for gestational age, gender, maternal education, Score for Neonatal Acute Physiology-II score, bronchopulmonary dysplasia, sepsis, and severe brain injury.

CONCLUSIONS:

Preterm infants treated with bevacizumab versus laser had higher odds of severe neurodevelopmental disabilities. Further investigation on the long-term safety of antivascular endothelial growth factor treatment of ROP is needed.
A ESCOLA E O ADOLESCENTE EM CONFLITO COM A LEI: DESVELANDO AS TRAMAS DE UMA DIFÍCIL RELAÇÃO
Authors: Cunha Eliseu de Oliveira , Dazzani Maria Virgínia Machado
Published: March 2016

RESUMO: O presente artigo teórico propõe-se a elencar e discutir possíveis razões da inamistosidade que, de modo geral, tem caracterizado a relação entre a escola e o adolescente em conflito com a lei no Brasil. Para tanto, empreendeu-se uma cuidadosa busca na literatura pertinente ao tema no intuito de desinvisibilizar e analisar criticamente os processos histórico-sociais dos quais essa tendência é tributária. O histórico alinhamento da escola com a cultura das classes abastadas, correlato à sua típica repulsa pelos estratos populares, revelou-se a espinha dorsal do fenômeno, uma vez que a maioria dos adolescentes em questão advém dessa classe social, sendo alvo privilegiado dos preconceitos, estigmas e estereótipos tipicamente atribuídos aos jovens de baixa renda. Para a atenuação desse quadro, a requalificação das práticas escolares para um efetivo acolhimento do adolescente mostra-se imprescindível.
Electrocardiographic Characterization of Ramucirumab on the Corrected QT Interval in a Phase II Study of Patients With Advanced Solid Tumors
Authors: Olszanski Anthony J. , Smith David C. , Camacho Luis H. , Thompson John , Ramalingam Suresh S. , Harvey R. Donald , Campos Luis , Ferry David , Tang Shande , Gao Ling , Safran Howard
Published: March 2016

Lessons Learned

Cardiotoxicity can be a serious complication of anticancer therapies. To enable earlier identification of drug-related cardiac effects, the International Conference on Harmonization (ICH) adopted the ICH E14 Guidelines for evaluating the potential for QT/corrected QT (QTc) interval prolongation and proarrhythmic potential for nonantiarrhythmic drugs. The results of the evaluation of ramucirumab on the QT/QTc interval show a lack of effect on QTc prolongation in patients with advanced cancer.

Background.

Ramucirumab is a human immunoglobulin G1 monoclonal antibody that specifically blocks vascular endothelial growth factor receptor-2 and is approved for the treatment of advanced gastric, non-small cell lung, and colorectal cancers. This phase II study was conducted to determine if treatment with ramucirumab causes prolongation of the corrected QT interval using Fridericia’s formula (QTcF) in patients with advanced cancer.

Methods.

Patients received intravenous ramucirumab (10 mg/kg) every 21 days for 3 cycles. The first 16 patients received moxifloxacin (400 mg orally), an antibiotic associated with mild QT prolongation as a positive control. During cycle 3, determination of QTcF prolongation was made with triplicate electrocardiograms at multiple time points to compare with baseline.

Results.

Sixty-six patients received therapy; 51 patients completed 9 or more weeks of therapy for the complete QTcF evaluation period. The upper limit of the 90% two-sided confidence intervals for the least square means of change in QTcF from baseline at each time point was less than 10 milliseconds. Concentration-QTcF analysis showed a visible, but not significant, negative association between ramucirumab concentration and QTcF change from baseline.

Conclusion.

Ramucirumab at a dose of 10 mg/kg administered every 21 days for 3 cycles did not produce a statistically or clinically significant prolongation of QTcF.
Towards quantum dot and device implementation with InP–GaAs–InP nanostructure
Authors: Purkayastha Tamoghna , De Debashis , Das Kunal , Ghatak Sayantan
Published: March 2016

Nanomaterial-based ultra-low-energy device design is one of the prime research areas in nanoscale computation. In ‘more-than-Moore’ technological trends, new device designs with quantum dot nanostructure have become an emerging domain of research. Various quantum dot-based devices, especially quantum dot cellular automata, have been designed both experimentally and by simulation. These quantum devices operate solely on the principle of charge localisation, which accounts for their high speed and ultra-low energy consumption. Quantum dots have an innate ability to confine electrons. As a result, quantum dot formation in a device is highly desirable in order to design quantum devices. Quantum dot implementation with interfacing indium phosphide (InP)–gallium arsenide (GaAs)–indium phosphide nanostructure and quantum dot formation within the redox centres of an allyl molecule are reported in this paper. The formation of the quantum dot is confirmed by the density-of-state studies conducted by the density functional theory calculation on the proposed nanostructures. The possibility of a new device design with two polarised states, namely ‘state x’ and ‘state x −1’, is also explored. Further, outlined in this paper is the design of quantum devices using Python coding, which makes it easier for a programmer to design any kind of complex nanostructure for nanoscale computation.
Impact of Money Supply on Sri Lankan Economy: An Econometric Analysis
Authors: Aslam A.L.M.
Published: March 2016

Economists argue that the money supply positively impact on economic growth of nations. In Sri Lankan context this statement was not tested econometrically. Therefore, the aim of this study was to scrutinize the impact of money supply on Sri Lankan economy. To exam this objective, this study considered the time series data from the period of 1959 to 2013 and used two types of variables such as dependent and independent variables. Here, the gross domestic product was considered as dependent variable, and Money supply, Exchange rate, Exports earnings, Imports outflow, the Colombo consumer price index were deemed as independent variables. In the meantime, the multivariate econometric method was used to test the impacts of money supply on economic growth of Sri Lanka. According to the analytical results, the money supply has kept positive impact on the economic growth of Sri Lanka at 1% significant level. The R-squared of the estimated model was 92% which was indicated that the estimated model was desirable. Meanwhile, the Durbin Watson test statistic was 2.43 and also the Breusch –Godfrey serial correlation LM test results was greater than 5%. Therefore, these statistics indicated that, the estimated model was not suffering from serial correlation.
Adaptive Adult Education in Terms of Active Use of Information Technologies
Authors: Desyatov Tymofiy
Published: March 2016

Adaptive systems of adult education are highlighted in the paper. It is noted that the purpose of adaptive education is to create adaptive environment of adult education which can provide opportunities for anticipatory adult education, development of mobile competent, creative person, who is able to adequately respond to dynamic life situations, to effectively solve problems and achieve a certain result. In this paper the content of education is defined as pedagogically adapted social experience. It is emphasized that education helps “to enter into life” and to adapt a person in it. But to be a specific adapter, education should be adapted to the realities of a person’s life, his (her) needs, which is especially important in adult education. It is theoretically proved that while incorporation into educational processes for different adult categories the necessity of adaptation arises: psychological (motivational), organizational-and-purposeful, content, technological, control-and-evaluational. It is investigated that the necessity of multilateral adaptation brought to life the concepts of “adaptive school” and “adaptive education”. Basic functions, principles, technologies and factors of activization of an adult’s educational-and-subjective activity are defined. It is emphasized that adaptive learning allows not only to adapt the learning process to the student, but also to ensure active involvement of the subject of study to designing of adaptive learning environment, to developing individual educational route.
PROCESSO DE CERTIFICAÇÃO DE SISTEMAS DE REGISTRO ELETRÔNICO DE SAÚDE NO BRASIL: UMA ABORDAGEM ABRANGENTE E OS PRINCIPAIS DESAFIOS
Authors: Araújo Bruno Gomes de , Valentim Ricardo Alexsandro de Medeiros , Hekis Helio Roberto , Júnior José Diniz , Tourinho Francis Solange Vieira , Alves Robinson Luís de Souza
Published: March 2016

O artigo tem como objetivo apresentar uma visão geral sobre o processo de Certificação de Sistemas de Registro Eletrônico de Saúde no Brasil, e listar os principais desafios enfrentados atualmente. Devido a crescente informatização dos processos que antes eram feitos de forma manual, existe uma constante busca pela segurança dos dados e processos envolvidos. Sistemas que manipulam informações importantes, sigilosas ou documentos eletrônicos que devem possuir validade jurídica, devem assegurar aos usuários a Autenticação, Confidencialidade, Integridade e o Não-repúdio dos dados. Neste sentido, várias técnicas são utilizadas atualmente, entre elas a Certificação Digital. Esta técnica consiste na emissão de um Certificado Digital, com informações que garantem a autenticidade de uma das entidades da comunicação, servindo como um documento de identificação eletrônico. No Brasil, os certificados digitais são emitidos pela ICP-Brasil. Este método já vem sendo utilizado na área da saúde, por exemplo, o CRM Digital, que consiste em um smart card que armazena um certificado com informações que identificam o médico. Mas, não basta a utilização desta técnica para que os sistemas na área da saúde sejam legalizados para serem utilizados no ambiente hospitalar, é preciso, além da segurança das informações, a garantia de que as suas funcionalidades estejam em completo funcionamento, pois estão relacionadas com informações e procedimentos importantes sobre a saúde dos pacientes, e qualquer erro pode comprometê-las. A partir disto, destaca-se a criação do processo de Certificação de Sistemas de Registro Eletrônico de Saúde, que consiste em uma verificação de conformidade dos sistemas baseado nos Requisitos de Conformidade definidos pelo Conselho Federal de Medicina e Sociedade Brasileira de Informática em Saúde.
SISTEMAS DE INFORMAÇÃO COMO APOIO À GESTÃO DE RECURSOS HUMANOS EM SAÚDE
Authors: Pereira Giveldna Maria Costa , Oliveira Idelmárcia Dantas de , Silva Rodrigo Dantas da , Hékis Hélio Roberto , Valentim Ricardo Alexsandro de Medeiros
Published: March 2016

Este artigo apresenta uma revisão na literatura, nacional e internacional, entre 2005 e 2015, sobre o tema “Sistemas de informação que apoiam à gestão de recursos humanos em saúde”, tendo como objetivo principal identificar quais sistemas de informação foram desenvolvidos para apoiar a gestão de recursos humanos em saúde. A metodologia adotada consistiu em duas etapas: Revisão bibliográfica e Análise detalhada do conteúdo. A pesquisa desenvolvida foi classificada como bibliográfica, exploratória e quantitativa. Os principais resultados desta pesquisa foram: 82,35% dos trabalhos são artigos científicos, publicados em 2009, 2010 e 2013, pela USP, UFPE e Universidade de Washington, na área de Ciências da Saúde; 74,02% dos estudos possuem abordagem qualitativa, 80,39% são do tipo bibliográficos e apresentam como principais focos de interesse a avaliação e explanação sobre a importância de sistemas de informação; a grande maioria dos sistemas identificados estão em produção, apresentando a estratégia de desenvolvimento Web e somente dois deles foram desenvolvidos para apoiar a gestão de recursos humanos em saúde. Por fim, foi proposta e apresentada a Plataforma Nacional de Recursos Humanos em Saúde - PlataformaRH do SUS, em desenvolvimento pelo LAIS/UFRN.
Vietnams Developing Markets: How Do Perceptions And Strategies In The Negotiation Process Differ From The U.S.?
Authors: Ready Kathryn J. , Dinh Van
Published: March 2016

Growth in international trade has had a profound effect on executives and managers in their need to better understand differences in effective cross-cultural negotiation skills. The recent opening up of trade with Vietnam points to a need to better understand how the Vietnamese negotiating style differs from the U.S. style as managers are called upon to recruit the best and brightest in an increasingly competitive labor market. In this paper, survey data, taken separately from university students in the U.S. and Vietnam, are used to examine differences in the negotiation process. The results confirmed that cultural differences lead to differences in perceptions and strategies employed in the negotiation process. Theoretical and practical implications for managers involved in negotiations with the Vietnamese as well as directions for future research are discussed.
The Anatomy Of EEOs Level Playing Field
Authors: Powers Edward L.
Published: March 2016

The election of President Barack Obama, and the candidacies of Hillary Clinton and Sarah Palin raise the issue of whether we continue to need equal employment opportunity and/or affirmative action. The concept of a level playing field is carefully developed, and provides a basis for a more thorough analysis of the future of equal employment opportunity and affirmative action.
The Perception Of Afghan-American Leaders Role In Economic Development Efforts In Afghanistan: A Study Of Gender Differences And Repatriation To The Motherland
Authors: Kaifi Belal A. , Mujtaba Bahaudin G. , Xie Yan
Published: March 2016

The majority of Afghanistans best educated and experienced generations of workers have become scattered expatriates living throughout the world. This brain-drain has taken place over a thirty-year period due to continuous violence, tragedy, and war throughout Afghanistan. As such, a rebuilding process now largely depends on the international community. This study of 58 male and 42 female Afghan-American respondents analyzes their perceptions regarding development opportunities in Afghanistan as well as their willingness to take part in the rebuilding process. It appears that there are some differences in the responses of males and females. The younger generation seems to be much more willing to go back and help in the rebuilding process. There seems to be a longevity effect: those who have been away from Afghanistan for a longer period of time are less willing to return for the rebuilding initiatives. Results and implications are presented.
Women As Drivers Of Japanese Firms Success: The Effect Of Women Managers And Gender Diversity On Firm Performance
Authors: Nakagawa Yukiko , Schreiber G. M.
Published: March 2016

While various theoretical arguments have been constructed that imply that a firm would see improved financial performance by increasing the proportion of women managers, previous studies on the issue, in Japan and elsewhere, have shown mixed results. Using data from Toyo Keizai and Nikkei NEEDS on 745 Japanese-listed companies, the authors investigate the impact of womens managerial participation and, more generally, overall workplace and managerial gender diversity on corporate performance. They find a robust significant positive relationship between firm performance and both female manager ratio and gender diversity, after controlling for industry, firm size, capital structure, corporate governance, and compensation policy. This relationship also exhibits substantial nonlinearity, with the benefit decreasing as the proportion of women managers or managerial gender diversity increases.
Enhancing Food And Nutrition Curricula In Higher Education By Assigning Collaborative Food System Assessment Projects
Authors: Matthews June
Published: March 2016

Student engagement in higher education is important. Some professional healthcare programs, however, can become quite focused and competitive, limiting the potential for positive student engagement and for students to see how their field of study fits within larger systems. Food system assessments are an ideal way to see the interconnectedness of all parts of a food cycle for a city or region. This case study describes food system assessments conducted by 165 undergraduate students in their first year of a Food and Nutritional Sciences program. Using collaborative, problem-based learning and a photovoice approach, the goal was to help students appreciate the entire food cycle, not just the consumption aspect that dominates much of nutrition education and practice. Students gleaned information about food production, processing, distribution, and waste from their site visits. They also calculated the food miles and CO2 emissions for two foods purchased in their assigned neighborhood. With their final reports, students submitted electronic versions of photographs, which were viewed and discussed during in-class focus groups. The potential for home/community food production prompted the most discussion. While logistics and collaborative learning presented some challenges, this participatory and reflective learning experience promoted positive student engagement among students in higher education. Educators in other university programs may consider enhancing their curricula by assigning collaborative food system assessment projects.
A Comparison Of Mission Statements Of National Blue Ribbon Schools And Unacceptable Texas High Schools
Authors: Perfetto John Charles , Holland Glenda , Davis Rebecca , Fedynich La Vonne
Published: March 2016

This study was conducted to determine the themes present in the context of high schools, to determine any significant differences in themes for high and low performing high schools, and to determine if significant differences were present for the same sample of high schools based on school size. An analysis of the content of mission statements identified 31 dominant themes: Students, Providing, All, Community, Learning, Academics, Developing, Responsible, Education, Environment, Preparing, Productive, Success, Lifelong Learning, Individual, Citizen, Excellence, Skills, Society, Committed, Promotes, Achievement, Diversity, Knowledge, Nature, Challenge, Future, Partnership, Quality, Potential, and Safe. Significant differences were found between the group of high and low performing high schools for the themes of Academics, Excellence, Challenge, Learning, Nurture, and Lifelong Learning (p ? .05). Analysis of mission statements grouped by size yielded a significant difference for the theme of Knowledge for large size high schools as compared to small and medium size high schools.
Differentiating Instruction: As Easy As One, Two, Three
Authors: Shepherd Carol , Acosta-Tello Enid
Published: March 2016

Using the Three Phase Lesson model, teachers identify prior knowledge that the student must possess in order to be successful in learning the new concepts. Teachers then delineate specific components inherent in the concepts that need to be mastered and identify tasks which will enable the student to practice these new concepts.
Strategies And Initiatives That Revitalize Wesley College STEM Programs
Authors: D'Souza Malcolm J. , Kroen William K. , Stephens Charlene B. , Kashmar Richard J.
Published: March 2016

Church-related small private liberal arts baccalaureate minority-serving institutions like Wesley College have modest endowments, are heavily tuition-dependent, and have large numbers of financially-challenged students. In order to sustain the level of academic excellence and to continue to build student demographic diversity in its accessible robust Science and Mathematics (STEM) programs, the faculty sought federal and state funds to implement a coordinated program of curriculum enhancements and student support programs that will increase the number of students choosing STEM majors, increase their academic success, and improve retention.
Flipping The Classroom: Turning An Instructional Methods Course Upside Down
Authors: Marks Diane B.
Published: March 2016

Higher education and teacher education in particular are entering a time of transformation.  With major forces like shifting demographics, new technologies, and the move from an industrial to an information society, teacher educators need not only to prepare teachers for new ways of teaching, but also must adopt and model best practices for these new teaching methods.  This study examines how several key strategies from Flipped Classroom theory can be adapted to an instructional methods course.  Findings show that with careful curriculum design, both content and methods learning objectives can be taught and mastered with Flipped Classroom methods.
Promoting Postformal Thinking In A U.S. History Survey Course: A Problem-Based Approach
Authors: Wynn Charles T. , Mosholder Richard S. , Larsen Carolee A.
Published: March 2016

This article presents a problem-based learning (PBL) model for teaching a college U.S. history survey course (U.S. history since 1890) designed to promote postformal thinking skills and identify and explain thinking systems inherent in adult complex problem-solving. We also present the results of a study in which the outcomes of the PBL model were compared to the outcomes of the same course taught with traditional lecture and discussion. The PBL model was more effective in scaffolding learning so that students recognize and practice postformal thinking dynamics and in facilitating self-reported student perceptions of increased course engagement and content relevance. We offer recommendations for implementing PBL in social science survey courses.
Higher Education Reform In Kyrgyzstan
Authors: Tolbaeva Guljan , McLean Gary N.
Published: March 2016

Kyrgyzstan, a former soviet republic in Central Asia, is currently going through a process of higher education reform to strengthen its system, many of the problems of which are a legacy of its soviet history. Reforms include the establishment of a national testing system for graduates of secondary education, the development of an ethics code to counter the buying of grades, the development of new programs and courses, the institution of higher education consortia, and others.
Project Managers: Born Or Made?
Authors: Lorenz Leslie , Dittman Kevin
Published: March 2016

As the world of project management expands, good project managers are becoming a valuable asset to have in an organization. These project managers must not only have an outstanding grasp of the basic project management principles, but the overall leadership skills to be successful. This paper will discuss the skills a project manager must have to be proficient and whether these skills are innate or can be imbibed over time. This paper will also examine personality traits of the exceptional project manager and whether personality assessments are able to predict the possibility of a career in project management. With this information, organizations can understand the value what good project managers can bring to their organization and why it is essential to find project managers that have the capabilities of leading projects successfully.