bluuebunny/crossref_metadata_2025 huggingface dataset:
PRÁTICAS DE LETRAMENTO DE UM ALUNO SURDO NO CONTEXTO DA PANDEMIA DA COVID-19
Authors: VIEIRA DA SILVA CLEUZILAINE , CARDOSO GOMES MARIA DE FÁTIMA
Published: January 2023

O presente trabalho aborda as práticas de letramento de um aluno surdo bimodal no contexto da pandemia da Covid-19. Consideramos o aluno bimodal por seu acesso mínimo à difusão da Libras e da Língua oral no 4º ano do ensino fundamental em uma escola estadual do interior de Minas Gerais. Para tanto, o trabalho se desenvolve com base em uma pesquisa etnográfica desenvolvida durante o ano de 2021, que faz parte da construção teórico-metodológica de uma tese de doutorado ainda em andamento. Para compor o material empírico, foram realizadas: observação participante; vídeo gravação das aulas, com anotações em caderno de campo; transcrição em mapas de eventos dos acontecimentos durante as aulas. Para a análise, elegemos um evento que evidencia os desafios das práticas de letramento por uma professora regente durante as aulas no contexto do ERE - Ensino Remoto Emergencial, para Otto, aluno surdo bimodal. Ancoramos nossas discussões na Teoria Histórico-Cultural, em diálogo com a Etnografia em Educação, e no conceito de práticas de letramento. Como resultado preliminar, encontramos um misto de desafios por parte da professora regente, tanto na condução das aulas com o PET (Plano de Estudos Tutorado), quanto no conjunto de práticas de letramento para o aluno surdo durante o período pandêmico.
PROCESSOS DE ADJETIVAÇÃO NO GÊNERO REPORTAGEM
Authors: CÍCERO FRANÇA BARBOSA JACKSON
Published: January 2023

Este trabalho relata uma experiência fruto de uma sequência didática aplicada no Cursinho Pré-Vestibular Solidário, da UFCG, realizada com vistas a analisar como se articulam processos de adjetivação nos aspectos linguísticos do gênero reportagem. Como o foco linguístico se desenvolveu acerca de construções adjetivas, o conhecimento a respeito da subordinação adjetiva também foi considerado. Dessa forma os conceitos construídos em relação à constituição das relativas, também foram apontados, seguindo as instruções relacionadas ao uso, em conformidade com aspectos sistêmico-funcionais, presentes no estudo de Duarte (2011), como por exemplo, o emprego da vírgula, de forma eficiente, bem como entendendo os seus processos de subjetividade e relações de sentido, presentes nas explicações, restrições e/ou nos apostos. Para endossar as reflexões teóricas abordadas, pautamo-nos em estudos que fundamentam, em relação ao ordenamento funcional, o uso de substantivos e adjetivos na construção do texto (PERINI, 2006; AZEREDO, 2010, 2011; TRAVAGLIA, 2004); termos da oração, coordenação e subordinação – na construção da argumentação (DUARTE, 2011; AZEREDO, 2010; FRANCHI,2006); reconhecimento de constituintes sintagmáticos (AZEREDO, 2010; PERINI, 2006); e por fim, como relacionar esses conhecimentos gramaticais em atividades de Análise linguística (BEZERRA & REINALDO, 2013: MENDONÇA, 2006; MATOS E SILVA, 2004). Avaliamos a estratégia teórico-metodológica, desenvolvida nas aulas, como válida e produtiva, uma vez que seu foco esteve na abordagem de categorias gramaticais articulada com os gêneros nos quais aparecem, sendo considerados, especificamente, os efeitos de sentido que o uso dessas categorias suscita no gênero em relevo.
AS RESTRIÇÕES E POSSIBILIDADES CURRICULARES COM ÊNFASE NO ENSINO DA LÍNGUA PORTUGUESA NO ENSINO REMOTO: UM ESTUDO A PARTIR DA EXPERIÊNCIA DE ESTÁGIO EM ESCOLA MUNICIPAL DE FORTALEZA – CEARÁ
Authors: TIMBÓ LIMA MORGANA , RODRIGUES DE OLINDA SAHMARONI , DE LIMA FERREIRA DÁVILLO
Published: January 2023

A emergência sanitária ocasionada pela pandemia do novo coronavírus demandou, para dirimir seus índices de contágio, períodos de isolamento social recomendado pela Organização Mundial da Saúde (OMS). Essas medidas necessárias influenciaram a dinâmica do processo de ensino das escolas, aderindo ao ensino remoto emergencial. A mudança da rotina de trabalho dos professores e as particularidades do ensino da Língua Portuguesa, fundamental para o pleno exercício das crianças na sociedade, puseram em evidência uma ampla gama de questões que precisariam ser acompanhadas na proposta curricular para que as práticas fossem bem sucedidas. O presente artigo tem como objetivo descrever o papel do professor como sujeito e como profissional, dentro do contexto pandêmico e do ensino remoto emergencial, e como este reverbera na composição do currículo possível e no ensino da Língua Portuguesa do 3º ano do Ensino Fundamental. Os procedimentos metodológicos adotados para tal fim consistiram em uma pesquisa bibliográfica, considerando autores que narram sobre a dimensão histórico-política da sociedade e do ensino da língua portuguesa, e uma pesquisa em campo de caráter analítico em uma Escola Municipal em Fortaleza. A pesquisa bibliográfica e a pesquisa em campo possibilitaram a devida compreensão do currículo possível e fundamentaram a implementação de práticas na turma de 3º ano, também relatada nesta obra. A partir deste estudo, pode-se concluir que, apesar das possibilidades apresentadas pelas tecnologias, o trabalho docente sofreu duras restrições e com limitado suporte administrativo na instância da escola pública. As fundamentações teóricas da prática auxiliam os docentes a resguardar qualidade para o processo de aprendizagem em Língua Portuguesa.
Partial Purification of Catalase Enzyme from Muscle Tissue of Dusky Spinefoot (Siganus luridus)
Authors: ÇEVİK Büşra , BAHADIR Sibel , EKİNCİ Deniz
Published: January 2023

Catalase, one of the antioxidant enzymes, decomposes hydrogen peroxide into water and oxygen. From the discovery of catalase, several studies have been carried out to reveal its importance in health, food and cosmetics industries etc., and these studies are still ongoing. In this study, catalase enzyme was partially purified from muscle tissue of Dusky spinefoot (Siganus luridus). Purification procedure consisted of homogenate preparation, ammonium sulfate precipitation and dialysis. The enzyme was precipitated in the range of 40-60 % Ammonium Sulfate concentration. The optimum buffer was determined as 200 mM phosphate buffer, optimum pH 8.0 and optimum substrate concentration 24mM for H₂ and O₂, respectively.
The Impact of Biotechnology Product Innovation and Corporate Strategy in Medium-Scale Seaweed Industry Companies on the Company Business Growth (Case Study: Ocean Fresh CV)
Authors:   MBA Student, Sekolah Bisnis dan Manajemen, Institut Teknologi Bandung, Indonesia, Buana Archie Sultan Eka , Ratnaningtyas Sudrajati ,   Professor, Sekolah Bisnis dan Manajemen, Institut Teknologi Bandung, Indonesia
Published: January 2023

A product innovation approach that can have a positive impact on both the environment and consumers is biotechnology. Seaweed, a material obtained from the sea, offers a lot of potential. Future prospects for several industries include the use of seaweed product innovation employing a biotechnology method. This research is based on business issues and how to maximize existing potential. This research aims to study the performance of the corporate strategy and the development of product innovation in a biotechnology-based company, namely Ocean Fresh CV. Data collection was carried out by means of semi-structured interviews with the directors of the company and analyzed by evaluating internal factors and discussing using the Balanced Scorecard approach. This study shows that the Company’s Strategy and Product Innovation carried out at Ocean Fresh CV have positively impacted business growth so far. The results of this analysis will be made in the form of a Matrix Scenario Planning to be able to provide business solutions that can be implemented by companies for future business growth.
Extensive Kaposi's sarcoma in a Patient with Acquired Immunodeficiency Syndrome: Case Report
Authors:   Department of Internal Medicine. High Specialty Hospital of Veracruz SESVER, Veracruz Mexico., Sánchez David Sandoval , Calixto Estanislao Antonio ,   Department of Internal Medicine. High Specialty Hospital of Veracruz SESVER, Veracruz Mexico., Juárez Roberto Peralta ,   Department of Infectology. Regional Hospital of Poza Rica SESVER, Veracruz Mexico., Aranda Marcos García ,   Department of Internal Medicine. High Specialty Hospital of Veracruz SESVER, Veracruz Mexico., Villalobos Rolando Castellanos ,   Department of Internal Medicine. High Specialty Hospital of Veracruz SESVER, Veracruz Mexico., Navarrete Jessica Ariatna Carreto ,   Department of Internal Medicine. High Specialty Hospital of Veracruz SESVER, Veracruz Mexico.
Published: January 2023

Kaposi's Sarcoma (KS) is an angioproliferative neoplasm, the causative agent is human herpes virus 8 and the second most frequent tumor after non-Hodgkin lymphoma related to the human immunodeficiency virus (VIH). We present the case of a 40-year-old male with no history of chronic diseases, who began his condition with adenopathies in the bilateral inguinal region, adding a productive cough, lymphedema, and skin lesions with nodular characteristics and bleeding ulcers. A positive HIV test was reported, and a biopsy was performed, showing evidence of a spindle cell neoplasm compatible with KS. Laboratories with hemoglobin 8.3 mg/dL, platelets 239,000/uL, leukocytes 7.29/uL, glucose 76 mg/dL, creatinine 2.2 mg/dL, urea 80 mg/dL, albumin 1.69 g/dL, TGO 18 IU/L, TGP 5 IU/L, DHL 189 IU/L, viral load 283,259 copies and CD4 192 cells. Chest and abdomen computed tomography with evidence of pleural effusion, and multiple retroperitoneal and inguinal adenopathies. Starting concomitant retroviral treatment with liposomal doxorubicin, improving clinical status and laboratory parameters. HIV-infected people are at high risk of developing KS, early initiation of antiretroviral therapy, and maintenance of high CD4 cell counts are essential to reduce the incidence.
Paradigm and Views of Women's Marriage in Culturs Positions
Authors:   Faculty of Law, Mpu Tantular University, Jakarta Indonesia, Panjaitan Junifer Dame
Published: January 2023

The results of this study show that marriage from a traditional perspective is still used today, as evidenced in several regions, in particular, they still apply customary marriage law in the midst of modern times. It is important for women that a traditional marriage is sacred, because it is a cultural variety for the Indonesian nation that is not shared by other countries. The customary marriage law certainly has its own characteristics which are different in every region in Indonesia. The difference lies in the subject, system, principles, forms and implementation as well as prohibitions which have their own characteristics from each region.
Leadership Communication Patterns Of Madrasa Principal In Internalizing Commendable Morals
Authors:   Faculty of Education and Training UIN Saizu Purwokerto Indonesia, Munjin Munjin
Published: January 2023

The communication patterns of a madrasa principal can be done in various ways to influence or motivate subordinates to achieve the organizational goals. This qualitative research aims to describe and analyze the communication pattern done by principal of State Madrasa of Eelementary 1 Banyumas. Observation, in-depth interviews, and documentation are data collection methods carried out to madrasa principal, teachers, and students. The results indicated that the communication patterns used by madrasa principal include communication, interactional, social-psychological, persuasive, and newcomb. In addition, he also uses written and oral communication on matters considered urgent and important. The conducive madrasa culture and the commitment of all madrasa members play a significant role in the implementation of communication model.
olitical Hegemony After The Regional Head Elections Of Bappeda Office In Bombana Regency, Southeast Sulawesi Province, Indonesia
Authors:   Magister of Cultural Studies Study Program, Post-Graduate Program of Halu Oleo University,Kendari, Indonesia, Irawan Ari , Suyuti Nasrudin , Syahrun Syahrun , Sifatu Wa Ode , Lindayani Lilik Rita , Bahtiar Bahtiar , Aso La ,   Department of Anthropology, Faculty of Cultural Sciences, Halu Oleo University,Kendari, Indonesia,   Department of Archeology, Faculty of Cultural Sciences, Halu Oleo University,Kendari, Indonesia,   Department of Language and Literature, Faculty of Cultural Sciences, Halu Oleo University,Kendari, Indonesia,   Department of Sociology, Faculty of Social and Political Sciences, Halu Oleo University,Kendari, Indonesia,   English Literature Study Program, Faculty of Cultural Sciences, Halu Oleo University,Kendari, Indonesia
Published: January 2023

Arresting positions and career snapshots in selection bureaucrats is based on the principles of the merit system, namely staffing management in the bureaucracy which focuses more on aspects of competence and employee competition as a basis for recruiting and promoting employees in the ranks of the bureaucracy. This research aims to describe the forms of political hegemony after the election of the Head of Bombana Region in Bombana Regency of BAPPEDA Office, Southeast Sulawesi Province. This research is qualitative. This research was conducted in BAPPEDA Office of Bombana Regency, Southeast Sulawesi Province, Indonesia. Data collection techniques used are observation, interviews, and documentation study. Data analysis techniques were carried out by collecting data, reducing data, presenting data (data display), and drawing conclusions. The results of this research showed that: The forms of political hegemony after the election of Bombana Regional Head in Bombana Regency BAPPEDA Office, Southeast Sulawesi Province, namely: (1) Increasing the discipline of civil servants, and (2) Increasing the loyalty of civil servants to Regional Head.
Small Micro And Medium Business Development Strategy(SMMBDS) In East Kolaka, Southeast Sulawesi Province, Indonesia
Authors:   Accounting Education Study Program, Faculty of Teacher Training and Education, Halu Oleo University, Kendari, Indonesia, Sabrin Sabrin , Amir Muh ,   Business Administration Study Program, Faculty of Social and Political Sciences, Halu Oleo University, Kendari, Indonesia, Asriani Asriani ,   Governmental Science Study Program, Faculty of Social and Political Sciences, Halu Oleo University, Kendari, Indonesia, Rahim Abdul , Aso La ,   Agricultural Product Technology Study Program, Faculty of Agriculture, Fisheries and Animal Husbandry, Nineteen November University, Kolaka,   Language and Literature Department, Cultural Studies Faculty, Halu Oleo University, Kendari, Indonesia
Published: January 2023

The economic growth and development of a region are inseparable from the potential of Small, Micro, and Medium Enterprises (SMMEs), because SMMEs have a significant contribution to the development of the regional Gross Regional Domestic Product (GRDP) as well as the national GRDP. Therefore, the study of research and development of SMEs is one of the basic prerequisites that must be carried out in building the business and economy of the community and the regional economy. This study aims to analyze the factors that support and promote SMME development and analyze SMME development in East Kolaka Regency, Southeast Sulawesi Province. The method used in this study was SWOT analysis. The results of the study found that the internal (strengths and weaknesses) and external (opportunities and threats) matrix analysis, the competitive position of the SMME sector in the Regency is in quadrant 1. In this position, the best strategic choices that can be made are growth strategies, market, and product development, as well as market penetration. The results of the SWOT analysis stated several recommendations for SMME development, namely: The need for support for MSME development because the right strategy can encourage SMMEs to continue to grow.
Implementation Stages Of Tamburu Barata Kahedupa Tradition On Kaledupa Ethnic Society In Wakatobi Regency, Southeast Sulawesi Province, Indonesia
Authors:   Magister of Cultural Studies Study Program Post-Graduate Program, Halu Oleo University, Kendari, Indonesia, Hagiarto Hagiarto , Dirman La Ode , Suraya Rahmat Sewa , Aso La ,   Oral Tradition Department, Cultural Studies Faculty, Halu Oleo University, Kendar, Indonesia,   Language and Literature Department, Cultural Studies Faculty, Halu Oleo University, Kendari, Indonesia
Published: January 2023

This research aims to describe the stages of the implementation of tamburu barata kahedupa tradition in Kaledupa Ethnic society in Wakatobi Regency, Southeast Sulawesi Province. This research is qualitative. Sources of data in this study consisted of primary data and secondary data. Primary data is data obtained through observation and interviews, while secondary data is data obtained through references, documents, or other reference books related to the topic of discussion in this study. Data collection techniques were carried out using observation, interviews, and documentation studies. Data analysis techniques were carried out as long as the research takes place since the researchers are in the field together with the data collection process, then proceed in more detail and systematically after all the data were collected. The results of this research showed that The stages in carrying out tamburu barata kahedupa tradition in Kaledupa Ethnic Society consist of three stages, namely (1) mofila'a (Wearing clothes) stage, which uses typical Kaledupa clothing that has been determined according to customary rules. (2) hefactu stage (Deciding a good time)) which is left to the commander or king as the person who has full responsibility for determining the best times for marriage, and (3) fila'a (walking) stage, namely all tammbu barata kahedupa personnel who are members of the escort or accompany the groom to the bride's house.
CHEMICAL COMPOSITION OF SKINS AND ITS INFLUENCE ON CHANGES IN RAW MATERIALS DURING THEIR STORAGE
Authors:   Lecturer, Department of chemistry, Fergana State University, Uzbekistan, Fergana, QIZI RASULOVA MAMURAKHON OBIDJON
Published: January 2023

The amount of minerals (ash) in the skin is small. These are mainly potassium and sodium salts (up to 0.4%), as well as small amounts (0.002-0.01%) of iron, copper, phosphorus, calcium, aluminum, etc. Potassium and sodium ions enter the skin with blood and lymph, iron ions - from blood hemoglobin, phosphorus is found in phospholipids, copper in the pigment, silicon, arsenic, calcium and magnesium in the epidermal layer.
Noncompliance with Medication Treatment: A Case Report of a Patient with Coronary Heart Disease
Authors:   General Hospital of Thoracic Diseases SOTIRIA, Athens, Greece, Theofilou Paraskevi
Published: January 2023

Medication compliance is a determining factor treatment effectiveness, as non-adherence reduces the optimum clinical benefit. Patients can experience significant positive changes such as improving their quality of life, increasing life expectancy, reducing of disease complications and risk of disability, reduction of clin progression of the disease, increase in the patient’s trust towards the doctor, increase the effectiveness of the drug and treatment.
To Analyze the Outcomes of Various Methods of Treatment of Periprosthetic Fracture Following Hip Arthroplasty- A Restrospective Study to form the Optimal Treatment Guidelines
Authors:   Delhi Institute of Trauma and Orthopaedics (DITO), Sant Parmanand Hospital, 18 Sham Nath Marg, Civil Lines, New Delhi, Delhi-110054, India, Verma Nikhil
Published: January 2023

Background: Periprosthetic fracture of femur after total hip arthroplasty (THA) is a well known complication. Mayo clinic joint registry has reported 1.1% incidence of periprosthetic femoral fractures after primary THA and 4% incidence after revision THA. This study was conducted to analyse the results of various methods of treatment of periprosthetic fractures following THA and to form the optimal treatment guidelines for fixation or revision surgeries.
Posttraumatic Popliteal Artery Course and Characteristics as Described by CT Angiography
Authors:   Department of Orthopedic Surgery, Harbor-UCLA Medical Center Carson, USA, George Jose
Published: January 2023

Introduction: Although rare, injuries to the popliteal artery are one of the most morbid complications in orthopedics, with severe sequelae. These injuries occur more frequently in previously injured extremities. We aim to quantify the relationship of the popliteal artery to the distal femur and proximal tibia using CTA in patients with and without a history of lower extremity trauma.
Divinités animales et entités hybrides en Égypte ancienne
Authors: Lenzo Giuseppina
Published: January 2023

Cet article présente une synthèse du rôle des animaux dans la religion égyptienne en se focalisant tout particulièrement sur le cas des entités hybrides. Alors que l’association avec un ou plusieurs animaux est l’une des caractéristiques des divinités égyptiennes, l’interprétation soulève plusieurs difficultés méthodologiques. Dans la plupart des cas, ces associations sont relativement simples, et mettent en rapport, selon des modalités diverses, un animal avec une divinité ; de telles relations sont alors relativement faciles à identifier et peuvent faire l’objet d’une typologie, en tout cas rudimentaire. Un cas de figure plus complexe est par contre posé par les représentations qui mobilisent non seulement un animal, mais aussi plusieurs motifs iconographiques à la fois. Le présent article commence par identifier les principales formes d’association d’animaux à des divinités, pour ensuite s’interroger plus longuement sur le cas des associations plus complexes, qui sont ici étudiées à partir de deux exemples paradigmatiques : les divinités protectrices et les habitants de la Douat ou monde souterrain.
La place de l’animal dans l’étude des religions antiques
Authors: Angelini Anna
Published: January 2023

Cet article commence par revenir sur certains thèmes et enjeux des contributions présentées dans le volume. Il évoque ensuite les problèmes liés aux paradigmes épistémologiques employés dans l’étude du rapport entre animaux et religions antiques, en proposant quelques pistes de réflexion pour la recherche sur ce thème.
Development of an abundance estimate for the eastern Bering Sea stock of beluga1 whales (Delphinapterus leucas)
Authors: Lowry Lloyd , Zerbini Alexandre , Frost Kathryn , DeMaster Douglas , Hobbs Roderick
Published: January 2023

The first dedicated aerial surveys for beluga whales in the Norton Sound/Yukon Delta region of Alaska were flown during May, June and September 1992. During May 1992 surveys, all of the survey area was covered with pack ice and only a few belugas were seen. In June 1992, many whales were seen in the region of Pastol Bay and the Yukon River Delta, with a few animals seen in eastern Norton Sound. In September 1992, whales were more dispersed and occurred both off the Yukon Delta and in coastal waters of northern Norton Sound. Based on those results, subsequent surveys were flown in June 1993–95 and 1999–2000. In all years except 1999 when there was extensive sea ice in the area, belugas were common off the Yukon Delta and in southern Norton Sound. In most years they were also seen in central Norton Sound. Density and abundance were estimated from the 2000 survey as it represented the most recent data and had the most complete and systematic coverage of the area. In June 2000, belugas were rare in the northern portion of Norton Sound, so the study area was reduced to central and southern Norton Sound and the Yukon Delta, which was divided into four strata by latitude. The density that was estimated with the model that received most Akaike Information Criterion support was 0.121 belugas km–2 and the number of belugas at the surface in the study area was estimated to be 3,497 (CV = 0.37). A generally accepted correction factor for availability of 2.0 was applied, resulting in an abundance estimate for the eastern Bering Sea beluga stock in June 2000 of 6,994 (95% confidence interval 3,162–15,472). This estimate is likely to be conservative. There are no previous abundance estimates for this region, so a population trend cannot be determined. The available evidence suggests that the current Alaska Native subsistence harvest from this stock is sustainable. Beluga consumption of prey populations is likely significant in the regional ecosystem and may have a particular impact on some stocks of Pacific salmon.
Influence of anthropogenic activities on marine mammal strandings in the estuary and northwestern Gulf of St. Lawrence, Quebec, Canada, 1994–2008
Authors: Larose-Truchon Marie-Hélène , Measures Lena , Brêthes Jean-Claude , Albert Elaine , Michaud Robert
Published: January 2023

Stranding records have long been used to monitor marine mammal mortalities and to help identify threats to populations. In coastal areas, marinemammals face numerous anthropogenic threats such as marine traffic and commercial fishing. The objective of this study was to investigate marinemammal stranding records from the St. Lawrence Estuary (SLE) and the northwestern Gulf of St. Lawrence (NWGSL), Quebec, Canada from 1994to 2008 for evidence of anthropogenic trauma caused by entanglement in fishing gear, ship collisions and gunshots. Of 1,590 marine mammalstranding records, 12% (n = 192) had evidence of anthropogenic trauma, most incidents being reported during summer when activities such asmarine traffic, most commercial fishing and recreational boating, occurred and a greater number of species were present in the area. These incidentswere classified into five categories (Incidental catch, Ship collision, Severe injury, Gunshot, Other). There were 1,245 mortalities and observationson carcasses suggested that anthropogenic trauma led to the death of 11% (141/1,245) of marine mammals: 14% (87/627) of cetaceans and 9%(54/618) of seals. Mortality of seals due to anthropogenic trauma was low, involving mainly Gunshot for grey (26% or 8/31) and harbour seals(26% or 8/31). Over the study period, marine mammal incidents with evidence of anthropogenic trauma increased significantly, driven by an increasein Incidental catch for two mysticete species, the common minke whale, 42% (39/92) and humpback whale, 13% (12/92) and Other for harbourporpoise 67% (16/24). Ship collision was the most common anthropogenic trauma for fin whales (22% or 8/36) and SLE beluga5 (22% or 8/36).Severe injury was reported for 22% (2/9) of small cetaceans and 78% (7/9) of seals. Evidence from some harbour porpoise stranding records(categorised as Other) suggests illegal hunting, incidental catch, predation or scavenging by grey seals in a marine protected area. The observedincrease in Incidental catch of common minke and humpback whales may be due to: (1) a shift in distribution of these two species into the SLE andNWGSL, possibly related to changes in the ecosystem; (2) changes in fishery practices; and (3) an increase in detection of marine mammal strandings.Anthropogenic trauma affecting marine mammals was documented including some species at risk, such as the harbour porpoise, the St. LawrenceEstuary beluga population, blue and North Atlantic right whales, in the St. Lawrence ecosystem including in a marine protected area. This studydemonstrates the usefulness of stranding records in helping to monitor human-caused mortality in marine mammal populations.
Standardization and quality control parameters evaluation on the Siddha mineral preparation: Linga chenduram
Authors: Soruban Thiruvancheeswaran , S Visweswaran , R Meenakumari
Published: January 2023

Standardization of herbal or herbo-mineral formulations is an important factor to assess the quality, purity, safety and efficacy of drugs. WHO has emphasized the need to ensure quality control of Indian Medicines including Siddha formulations by using modern techniques and by applying suitable parameters for Standardization of Linga Chenduram where Lingam (Cinnabar) is the primary constituent was selected for evaluation of Standardization and quality control parameters. Analysis of the drug showed that LC was dark brown in colour, odourless, tasteless, fine powder in appearance and fine to touch which indicates the completion of calcination process. In physicochemical analysis values of the drug such as loss on drying, total ash, water-soluble ash and acid insoluble ash were found to be 1.19%. 3.73%, 0.19% and 1.49% respectively. The total ash value indicated the absence of impure substances in LC. The XRD Analysis of Linga Chenduram showed that it was a highly crystalline drug. SEM analysis of Linga Chenduram showed that most of the particles present in the sample were Nano size and the results showed that the values of Mercury (51.21) and Carbon (43.63) were present in larger amount compared to Oxygen and Magnesium. The ICP-OES result showed that the toxic heavy metals such as Lead, Cadmium, Cupper, Potassium, Magnesium, Iron, Zinc, Nickel and Sodium were below the detection limit (BDL). Thus it is evident that the safety of siddha medicine had been proved in the modern scientific way. The end of the study concluded that the end product Linga Chenduram yields standard and safety.
Modelo de ventilador artificial UTN contra Covid 19
Authors: Vargas Badilla Ana Beatriz , Salazar Agüero Heriberto
Published: January 2023

Objetivo. Explicar el desarrollo y descripción del primer modelo de ventilador respiratorio elaborado en la Universidad Técnica Nacional (Costa Rica), desde su conceptualización, organización, ensamblaje, ensayos y puesta en marcha, desde el contexto mecánico hasta la tecnicidad digital, llevado a cabo por estudiantes de la carrera Ingeniería Electrónica bajo la supervisión y guía de los autores de este artículo, el cual se convirtió en un destacable trabajo para la comunidad universitaria. Resultados. Los principales resultados proponen tabla de costos, fórmulas matemáticas en función a las variables que caracterizan el tema de la respiración, velocidad y periodos de inhalación y exhalación que se conjuntan con los elementos digitales y mecánicos hasta convertir en un dispositivo funcional para la salud. Conclusiones. Se creó un modelo funcional y económico que permite salvaguardar la vida, aplicando materiales PLA, hierro sobre una bomba ambu, gracias a un lenguaje de programación que favorece el control del dispositivo en el motor.
Bibliometría y métricas alternativas: Aportes de la producción científica en Scopus Elsevier (1999-2020) para las políticas públicas sobre juventudes
Authors: Gómez Brenes Carmen
Published: January 2023

Objetivo. Analizar los aportes teóricos y metodológicos de la producción científica registrada en Scopus Elsevier, correspondiente al período 1999-2020, acerca de juventudes, relaciones intergeneracionales e intrageneracionales para la formulación, implementación y evaluación de política pública. Metodología. Se utilizaron métricas bibliográficas tradicionales y alternativas siguiendo estos pasos: 1. Identificación de palabras claves acerca del tema de juventudes y políticas públicas, 2. Definición de la ecuación de búsqueda, 3. Generación de base de datos con artículos científicos en el tema de interés, 4. Revisión documental y análisis de la información, 5. Evaluación de métricas tradicionales y alternativas. Resultados. Se tiene que 5 de 74 artículos científicos identificados sobre el tema de juventudes y relaciones inter e intrageneracionales, fueron utilizados en documentos de política en Suiza, Australia, Estados Unidos de Norteamérica y Reino Unido. Conclusiones. Los artículos científicos encontrados se orientan al uso del enfoque participativo que reconoce la pertinencia de la participación, voz e involucramiento de las niñas, niños y personas jóvenes para la creación de un conocimiento relacional que contemple la intergeneracionalidad y la interseccionalidad
Maternale veerkracht en sociale ongelijkheid tijdens de perinatale periode: mogelijke preventie en vroege interventiestrategieën
Authors: Vos S. , Van den Bergh B. , Roels H.A. , Martens D. , Kindermans H. , Nawrot T.S.
Published: January 2023

Maternal resilience and social inequality during the perinatal period: possible prevention and early intervention strategies

Maternal mental wellbeing during the first 1,000 days (from conception until the first years of life) is of crucial importance for the development and health later in life. In part 1 of this article, the current state of knowledge on maternal wellbeing, social inequality and the underlying biological mechanisms was summarized. In this part, the concept of psychological resilience and the potential early intervention and prevention strategies are discussed.
Género y teletrabajo: El caso de las trabajadoras del programa Uruguay Crece Contigo
Authors: Batthyány Karina , Katzkowicz Sharon , Scavino Solari Sol
Published: January 2023

En este artículo problematizamos la profundización de la división sexual del trabajo en las trabajadoras remuneradas del cuidado en Uruguay durante la pandemia por la COVID-19 y el cambio a la modalidad de teletrabajo. A partir de la selección del Programa Uruguay Crece Contigo como caso en donde observar el vínculo entre política pública y cuidados en la infancia por parte de las trabajadoras del Programa, fueron realizadas 26 entrevistas en profundidad a supervisoras, facilitadoras y operadoras de cercanía, recogiendo sus experiencias sobre el trabajo en pandemia. Esto permitió reflexionar en torno a dos ejes fundamentales: 1) las garantías para poder sostener el trabajo remunerado y los cuidados en pandemia y 2) los mecanismos redistributivos del cuidado entre Estado y familias y mujeres y varones. Se constató que el shock de la pandemia encontró un Estado que estaba comenzando a desarrollar sus políticas de cuidados que no respondió en términos ni materiales ni simbólicos a las necesidades tanto de las trabajadoras del cuidado, como de las poblaciones con mayores niveles de necesidades de cuidados, como las infancias. aprendizajes horizontales que se dan en la interacción entre pares juegan un rol fundamental en el desempeño profesional.
Uso y desarrollo de la lengua oral en el aula rural: Cambio de paradigmas educativos
Authors: Castillo Mardones Pamela Soledad , Gràcia Marta
Published: January 2023

Mucho se ha dicho sobre la escuela en diversos contextos, pero poco se han visibilizado los desafíos y oportunidades que enfrentan las escuelas que se ubican en la ruralidad chilena. En este sentido, a partir de la importancia del desarrollo de la competencia comunicativa, consideramos necesario conocer, desde la mirada del profesorado, sus historias comunicativas en relación con el modo en que acompañan el uso y desarrollo de la lengua oral en su alumnado de procedencia rural. En este artículo se analiza las percepciones y estrategias de uso y desarrollo de la lengua oral en el aula, según docentes que se desempeñan en escuelas rurales, considerando su historia escolar y familiar. Contamos con ocho docentes de dos regiones del país que participaron de entrevistas elaboradas a partir de la Escala EVALOE. Los principales hallazgos se relacionan con la identificación de factores que influyen en la competencia comunicativa en el contexto rural, y en un perfil de docentes que, pese a múltiples barreras, está promoviendo instancias favorecedoras de esta y otras competencias. Los resultados se discuten según literatura relacionada con la reflexión docente, la competencia comunicativa, y la escuela como entorno natural de desarrollo de esta competencia.
Inclusión, igualdad y asimilacionismo en escuelas con diversidad socioeconómica
Authors: Mendoza-Horvitz Manuela
Published: January 2023

Este artículo presenta el análisis de los hallazgos de un estudio de caso en dos escuelas chilenas con niveles excepcionales de heterogeneidad socioeconómica entre sus estudiantes, ello previo a la implementación de políticas educacionales que buscan reducir la segregación e incrementar la diversidad social en las escuelas, como es la Ley de Inclusión. Guiado por una discusión de los conceptos de Pierre Bourdieu, el análisis de entrevistas con profesores y directivos revela una actitud ambivalente hacia las diferencias y mixtura socioeconómicas en las escuelas. Por una parte, estas diferencias son valoradas y asociadas a beneficios para todos los estudiantes, principalmente el desarrollo de disposiciones igualitarias, como son las actitudes para relacionarse de manera respetuosa y empática con otros. Por una parte, estas diferencias son valoradas y asociadas a beneficios para todos los estudiantes, principalmente el desarrollo de disposiciones igualitarias, como son las actitudes para relacionarse de manera respetuosa y empática con otros. Por otra parte, se busca invisibilizar las diferencias socioeconómicas en el cotidiano para promover la igualdad social en el espacio escolar. Se argumenta que dicha invisibilización es articulada a costa de la asimilación de los estudiantes más pobres, lo cual plantea limitaciones para la inclusión social en estas escuelas pese a su excepcional apertura a la mezcla. Se discute algunos elementos clave a considerar para la promoción de una inclusión escolar no asimilacionista y de la convivencia democrática.
Insulin-like growth factor type 2 is a better survival marker than insulin-like growth factor type 1 in patients after acute decompensated heart failure
Authors: Bronisz Agata , Myśliwiec Bartosz J. , Hagner–Derengowska Magdalena , Xerri de Caro John , Bronisz Marek
Published: January 2023

Introduction

A decreased insulin-like growth factor 1 (IGF-1) level has been found in heart failure (HF). There are no reports assessing IGF-2 in HF, although in vitro research has shown that IGF-2 stimulates cardiomyocyte proliferation more than IGF-1. The study aim was to compare the IGF-1 and IGF-2 concentrations depending on HF exacerbation and annual survival.

Material and methods

Among 75 patients hospitalized due to newly diagnosed or exacerbated HF, the following evaluations were performed: anthropometric measurements, basic laboratory tests, heart echocardiography, and IGF-1 and IGF-2 concentrations. The annual survival was assessed. The participants were divided into NYHA II and NYHA III/IV groups. They did not differ in age, gender, body mass index (BMI), waist-hip ratio, glycated hemoglobin (HbA1c), high-density lipoprotein cholesterol, or triglycerides, but differed in echocardiographic parameters, BNP, total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol levels. Nine (12%) patients died during the 12-month follow-up.

Results

There were no differences in IGF-1 between NYHA groups and depending on the BMI, carbohydrate metabolism disorders and annual survival. A significantly lower IGF-2 concentration was found in NYHA III/IV vs. NYHA II: 583.71 (162.35) vs. 676.08 (172.09), p = 0.02, and in those who died: 501.47 (172.89) vs. 645.31 (166.17) nmol/l, p = 0.04. There was a positive correlation between IGF-2 and TC: r = 0.28, p = 0.015 and LDL: r = 0.29, p = 0.011 in the whole group and among patients with BMI ≥ 25 kg/m2: respectively for TC (r = 0.31, p = 0.014) and LDL (r = 0.28, p = 0.028). No IGF-1 correlation was found.

Conclusions

Reduced IGF-2 concentration is a better marker of patients with more advanced HF and a higher 1-year death risk than low IGF-1. Its secretion may depend on the cholesterol concentration.
Abrocitinib (Cibinqo)
Authors: CADTH
Published: January 2023

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.

The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.

This review assesses abrocitinib (Cibinqo), 200 mg, 100 mg, 50 mg, oral tablets.

Indication: Cibinqo (abrocitinib) is indicated for the treatment of patients 12 years and older with refractory moderate-to-severe atopic dermatitis, including pruritus, who have had an inadequate response to other systemic drugs (e.g., steroid or biologic), or for whom these treatments are not advised.
Monitoring sudden stratospheric warmings under climate change since 1980 based on reanalysis data verified by radio occultation
Authors: Li Ying , Kirchengast Gottfried , Schwaerz Marc , Yuan Yunbin
Published: January 2023

Abstract. We developed a new approach to monitor sudden stratospheric warming (SSW) events under climate change since 1980 based on reanalysis data verified by radio occultation data. We constructed gridded daily mean temperature anomalies from the input fields at different vertical resolutions (basic-case full resolution, cross-check with reanalysis at 10 stratospheric standard pressure levels or 10 and 50 hPa levels only) and employed the concept of threshold exceedance areas (TEAs), the geographic areas wherein the anomalies exceed predefined thresholds (such as 30 K), to monitor the phenomena. We derived main-phase TEAs, representing combined middle- and lower-stratospheric warming, to monitor SSWs on a daily basis. Based on the main-phase TEAs, three key metrics, including main-phase duration, area, and strength, are estimated and used for the detection and classification of SSW events. An SSW is defined to be detected if the main-phase warming lasts at least 6 d. According to the strength, SSW events are classified into minor, major, and extreme. An informative 42 winters' SSW climatology (1980–2021) was developed, including the three key metrics as well as onset date, maximum-warming-anomaly location, and other valuable SSW characterization information. The results and validation against previous studies underpin that the new method is robust for SSW detection and monitoring and that it can be applied to any quality-assured reanalysis, observational and model temperature data that cover the polar region and winter timeframes of interest, either using high-vertical-resolution input data (preferable basic case), coarser standard-pressure-levels resolution, or (at least) 10 and 50 hPa pressure level data. Within the 42 winters, 43 SSW events were detected for the basic case, yielding a frequency of about 1 event per year. In the 1990s, where recent studies showed gaps, we detected several events. Over 95 % of event onset dates occurred in deep winter (December–January–February timeframe, about 50 % in January), and more than three-quarters have their onset location over northern Eurasia and the adjacent polar ocean. Regarding long-term change, we found a statistically significant increase in the duration of SSW main-phase warmings of about 5(±2) d over the climate change period from the 1980s to the 2010s, raising the average duration by nearly 50 % from about 10 d to 15 d and inducing an SSW strength increase of about 40(±25) million km2 days from about 100 to 140 million km2 days. The results are robust (consistent within uncertainties) across the use of different input data resolutions. They can hence be used as a reference for further climate-change-related studies and as a valuable basis for studying SSW impacts and links to other weather and climate phenomena, such as changes in polar-vortex dynamics and in mid-latitude extreme weather.
Mercury in the free troposphere and bidirectional atmosphere–vegetation exchanges – insights from Maïdo mountain observatory in the Southern Hemisphere tropics
Authors: Koenig Alkuin M. , Magand Olivier , Verreyken Bert , Brioude Jerome , Amelynck Crist , Schoon Niels , Colomb Aurélie , Ferreira Araujo Beatriz , Ramonet Michel , Sha Mahesh K. , Cammas Jean-Pierre , Sonke Jeroen E. , Dommergue Aurélien
Published: January 2023

Abstract. Atmospheric mercury (Hg) observations in the lower free troposphere (LFT)
can give important insights into Hg redox chemistry and can help constrain
Hg background concentrations on a regional level. Relatively continuous
sampling of LFT air, inaccessible to most ground-based stations, can be
achieved at high-altitude observatories. However, such high-altitude
observatories are rare, especially in the Southern Hemisphere (SH), and
atmospheric Hg in the SH LFT is unconstrained. To fill this gap, we
continuously measured gaseous elemental mercury (GEM; hourly) and reactive
mercury (RM; integrated over ∼ 6–14 d) for 9 months at
Maïdo mountain observatory (2160 m a.s.l.) on remote Réunion Island
(21.1∘ S, 55.5∘ E) in the tropical Indian Ocean. GEM
exhibits a marked diurnal variation characterized by a midday peak (mean:
0.95 ng m−3; SD: 0.08 ng m−3) and a nighttime low (mean: 0.78 ng m−3; SD: 0.11 ng m−3). We find that this diurnal variation is
likely driven by the interplay of important GEM photo-reemission from the
islands' vegetated surfaces (i.e. vegetation + soil) during daylight hours
(8–22 ng m−2 h−1), boundary layer influences during the day,
and predominant LFT influences at night. We estimate GEM in the LFT based on
nighttime observations in particularly dry air masses and find a notable seasonal variation, with LFT GEM being lowest from December to March (mean 0.66 ng m−3; SD: 0.07 ng m−3) and highest from September to
November (mean: 0.79 ng m−3; SD: 0.09 ng m−3). Such a clear GEM
seasonality contrasts with the weak seasonal variation reported for the SH marine boundary layer but is in line with modeling results, highlighting the added value of continuous Hg observations in the LFT. Maïdo RM is 10.6 pg m−3 (SD: 5.9 pg m−3) on average, but RM in the cloud-free LFT
might be about twice as high, as weekly–biweekly sampled RM observations are likely diluted by low-RM contributions from the boundary layer and clouds.
Laser-induced sublimation extraction for centimeter-resolution multi-species greenhouse gas analysis on ice cores
Authors: Mächler Lars , Baggenstos Daniel , Krauss Florian , Schmitt Jochen , Bereiter Bernhard , Walther Remo , Reinhard Christoph , Tuzson Béla , Emmenegger Lukas , Fischer Hubertus
Published: January 2023

Abstract. Precision, accuracy, and temporal resolution are key to making full use of atmospheric trace gas records in ice cores. These aspects will become especially crucial for ice cores that aim to extend the ice core record to the last 1.5 Myr, i.e., across the Mid-Pleistocene Transition (as currently drilled within the European project Beyond EPICA – Oldest Ice Core (BE-OIC)). The ice from this period is expected to be close to bedrock and, due to glacier flow, extremely thinned with 15 000 years of climate history contained in only 1 m of ice. Accordingly, for a century-scale resolution, the sample vertical extent must be reduced to a few centimeters containing only about 1–2 mL air STP. We present a novel combined system for the extraction and the simultaneous measurement of CO2, CH4, and N2O concentrations, as well as δ13CO2, which achieves a vertical resolution of 1–2 cm (3.5×3.5 cm cross section) with precisions of 0.4 ppm, 3 ppb, 1 ppb, and 0.04 ‰, respectively, in sublimation tests with standard gas over gas-free ice. This is accomplished by employing a directional and continuous laser-induced sublimation followed by analysis of the sample gas by a quantum cascade laser absorption spectrometer (QCLAS). Besides the low sample volume requirements and the vertical resolution capabilities, the described method holds additional advantages over previous methods, including the immunity of the highly specific QCLAS analysis to drilling fluid contamination as well as the non-destructive nature of the spectroscopic gas analysis.
The combined extraction and analysis system was extensively tested by sublimating gas-free ice with introduction of a standard gas to determine the accuracy and characterize potential artifacts. Moreover, Antarctic ice samples were measured to confirm the measurement performance, covering the range of variability expected in Pleistocene ice and highlighting the vertical resolution capabilities critical for its application within BE-OIC.