bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural characterization and crystal packing of the isoquinoline derivative
Authors: Vrabel Viktor , Svorc Lubomir , Sivy Julius , Marchalin Stefan , Safar Peter
Published: September 2018

We report the crystal and molecular structure of a new isoquinoline-derivative, namely methyl O-[(11R, 11aS)-4-oxo-1, 3, 4, 6, 11, 11a-hexahydro-2H-pyrido[1, 2-b]isoquinolin-11-yl]carbonodithioate (I), C15H17NO2S2, which crystallizes in the non-centrosymmetric space group P212121 and its absolute structure was confirmed by anomalous dispersion effects in diffraction measurements on the crystals. Two central six-membered heterocyclic rings adopt a distorted half-chair conformation. The molecules are linked by a combination of weak C—H∙∙∙O, C—H∙∙∙S, C—H∙∙∙p inter- and intra-molecular interactions resulting in a three-dimensional network in the crystal structure. Crystal Data for C15H17NO2S2 (M =307.41 g/mol): orthorhombic, space group P212121 (no. 19), a = 5.2804(5) Å, b = 8.1347(17) Å, c = 35.015(4) Å, V = 1504.1(4) Å3, Z = 4, T = 298(2) K, μ(MoKα) = 0.354 mm-1, Dcalc =1.358 g/cm3, 20270 reflections measured (5.522° ≤ 2Θ ≤ 50.69°), 2757 unique (Rint = 0.0346, Rsigma = 0.0203) which were used in all calculations. The final R1 was 0.0389 (I > 2σ(I)) and wR2 was 0.0965 (all data).
Simultaneous spectrophotometric determination of drugs lacking peak maxima in their zero-order profiles by graphical or statistical representation of data
Authors: Magdy Ragaa , Hemdan Ahmed , Fares Nermine Victor , Farouk Maha
Published: September 2018

Trandolapril has no sharp peak in its zero-order spectrum, therefore it is difficult to be measured by direct spectrophotometry. In this study, direct univariate spectrophotometric methods were developed and validated for determination of Trandolapril and Verapamil combination in pure and tablet dosage forms. The first method for measuring both Trandolapril and Verapamil is Absorbance Subtraction (AS), this method depends on the presence of iso-absorptive point in the zero-order curve at 217 nm. It has the advantage of measuring the concentration of both Trandolapril and Verapamil from unified regression equation at the iso-absorptive point. The second, third and fourth methods were applied on the first order spectra of the studied drugs. Second method is Derivative Subtraction (DS) for Trandolapril and Derivative subtraction followed by spectrum subtraction (DS-SS) for Verapamil. The third and fourth methods are constant value and concentration value methods. In the concentration value method, the concentration of the drugs is determined from the graphical representation without the use of regression equations. All the developed methods were validated as per International Conference on Harmonization guidelines and the results proved that the developed methods are simple, accurate, and selective. Moreover, a statistical comparison between the developed methods and a reference method was done. Also, One-way ANOVA statistical test was done between all the proposed spectrophoto-metric methods and results showed no significant differences.
Biosorption of Cr(III) from aqueous solution using an agricultural by-product jute stick powder: Equilibrium and kinetic studies
Authors: Uddin Mohammad Nasir , Alam Jahangir , Naher Syeda Rahimon
Published: September 2018

The adsorption capacity of chromium(III) from synthetic waste water solution by a low cost biomaterial, Jute Stick Powder (JSP)was examined. A series of batch experiments were conducted at different pH values, adsorbent dosage and initial chromium concentration to investigate the effects of these experimental conditions. To analyze the metal adsorption on to the JSP, most common adsorption isotherm models were applied. To study the reaction rate, the kinetic and diffusion models were also applied. The morphological structure and variation of functional groups in the JSP before and after adsorption was examined by scanning electron microscope (SEM) and Fourier transform infrared spectrometry (FT-IR). Maximum chromium removal capacities of JSP was 84.34%with corresponding equilibrium uptake 8.4 mg/g from 50 mg/L of synthetic metal solution in 60 minutes of contact time at pH = 6.0 and 28 °C with continuous stirring at 180 rpm. The percent sorption of the biomass decreased with increasing concentration of metal ion but increased with decreasing pH, increasing contact time and adsorbent doses. Data for this study indicated a good correspondence with both isotherms of Langmuir and Freundlich isotherm. The analysis of kinetic indicated that Chromium was consistent with the second-order kinetic adsorption model. The rate of removal of Cr(III) ions from aqueous solution by JSP was found rapid initially within 5-30 minutes and reached in equilibrium in about 40 minutes. The investigation revealed that JSP, a low cost agricultural byproduct, was a potential adsorbent for removal of heavy metal ions from aqueous solution.
Application of Hammett equation to intramolecular hydrogen bond strength in para-substituted phenyl ring of trifluorobenzoylacetone and 1-aryl-1,3-diketone malonates
Authors: Darugar Vahidreza , Vakili Mohammad , Tayyari Sayyed Faramarz , Kamounah Fadhil Suleiman , Afzali Raheleh
Published: September 2018

The stability of two stable cis-enol forms in two categories of β-diketones, including para-substituted of trifluorobenzoylacetone (X-TFBA) and 1-aryl-1,3-diketone malonates (X-ADM, X: H, NO2, OCH3, CH3, OH, CF3, F, Cl, and NH2) has been obtained by different theoretical methods. According to our results, the energy difference between the mentioned stable chelated enol forms for the titled compounds is negligible. The theoretical equilibrium constants between the two stable cis-enol of the mentioned molecules are in excellent agreement with the reported experimental equilibrium constant. In addition, the effect of different substitutions on the intramolecular hydrogen bond strength has been evaluated. The correlation between Hammett para-substituent constants, σp. with the theoretical and experimental parameters related to the strength of hydrogen bond in p-X-TFBA and p-X-ADM molecules also investigated by means of density functional theory calculations. The electronic effects of para-substitutions on the intramolecular hydrogen bond strength were determined by NMR and IR data related to intramolecular hydrogen bond strength, geometry, natural bond orbital results, and topological parameters. These parameters were correlated with the Hammett para-substituent constants, σp. Good linear correlations between σp and the several parameters related to the hydrogen bond strength, in this study were obtained.
Comparison of the leaving groups during the study of the aquation of halopentaammine cobalt(III) complex in tartarate at different percentage of tert-butanol
Authors: Zeitouni Farah Samih , Amira Mohammad Fawzi , El-Subruiti Gehan Moustafa , Younes Ghassan Omar
Published: September 2018

The experimental kinetic study of aquation for both complexes bromopentaammine cobalt(III) and chloropentaammine cobalt(III) ions in the presence of tartarate solution in mixed solvent media of water with tert-butanol (10-50%, v:v) was examined spectrophotometrically at different temperatures (30-60 °C) by comparing the special effects of the leaving group of chloro and bromo on the rate constant of aquation. Comparison of kip (rate constant of ion-pairing) for both complexes and show the non-linear plots of log (kip) ion-pair rate constants against the reciprocal of the dielectric constant D. The thermodynamic analyses of the kinetic data for both complexes have been discussed in terms of solvent effect on the ion-pair aquation reactions. The obtained isokinetic temperatures of these systems indicate the existence of compensation effect arising from solute-solvent interaction. The excessive change of ΔHip* and ΔSip* with the mole fraction of the co-solvent can be recognized to the change of the physical properties of the solvent-water mixture with the solvent structure. Undersized changes in ΔGip* with the mole fraction of the co-solvent was found, representing a compensating effects between ΔHip* and ΔSip*.
Eco-friendly and simple synthesis of some non-natural flavones through chalcones
Authors: Rahman Mohammad Saidur , Alam Sayeda Shakila , Happy Kamrunnahar , Hossain Mohammad Mamun , Islam Mohammad Khademul , Biswas Foni Bushon
Published: September 2018

A distinctive feature of polyphenolics is the possession of biological properties such as antioxidant and antimicrobial activities. Simple synthesis and study about such important class of compounds and their analogs are very important to enhance the understanding of their role in human health and diseases. Accordingly, a series of chalcones (2a-f) have been synthesized by Claisen-Schmidt condensation reaction with required acetophenones and aromatic aldehydes in high yields. The conversion of chalcones to the corresponding flavones (1a-g) taking minimal amount of dimethyl sulfoxide with iodine in presence of sulfuric acid was carried out under microwave conditions in high yields.
Development and validation of second derivative and synchronous spectrofluorimetric methods for determination of oxytocin and ergometrine maleate in their combined formulation
Authors: Rizk Mohamed , El-Alamin Maha Mahmoud Abou , Moawad Mervat Isaac
Published: September 2018

Simple and sensitive second derivative and synchronous spectrofluorimetric methods have been developed and validated for the quantitative determination of oxytocin and ergometrine maleate in their pure and combined dosage forms. The methods are based on the derivatization reaction of oxytocin with fluorescamine reagent, which yielded a highly fluorescent compound measured at 486 nm after excitation at 390 nm. Ergometrine was directly measured in combination with oxytocin, since it exhibits native fluorescence at 421 nm after excitation at 300 nm. Quantitation of oxytocin in presence of ergometrine was also successful at 482 and 477 nm using second derivative and synchronous spectrofluorimetry, respectively. Different experimental parameters were studied and optimized. The relative fluorescence intensity versus concentration plot was rectilinear over the range of 0.04-0.75 and 5-100 ng/mL for oxytocin and ergometrine, respectively. The methods were successfully applied for the determination of both drugs in their prepared combined ampoules. The methods were validated and compared with the reference chromatographic method; they revealed good accuracy and reproducible results. The proposed methods showed high accuracy and sensitivity, with no requirement of multiple steps or previous chemical separation.
Development of spectrofluorimetric stability indicating method for determination of naratriptan hydrochloride in pharmaceutical dosage form
Authors: Rizk Mohamed , Sultan Maha , Elshahed Mona , Ali Mourad
Published: September 2018

A stability indicating spectrofluorimetric method is developed for the determination of naratriptan hydrochloride in pharmaceutical formulation. The proposed method is based on investigation of the native fluorescence spectral behaviour of the drug in aqueous phosphate buffer (pH = 7.0±0.2).The fluorescence intensity is measured at 355.0 nm after excitation at 230.0 nm. The fluorescence-concentration plot is linear over the concentration range 8.0-80.0 ng/mL, with lower detection limit of 2.6 ng/mL and quantification limit of 7.6 ng/mL. The method is successfully applied to the analysis of the studied drug in its commercial tablet. Furthermore, the proposed method is applied in dissolution study of tablet; the results are in good agreement with those obtained with the reference method. The proposed method is approved to be a stability-indicating assay after exposure of the drug to different forced degradation conditions, such as acidic, alkaline and oxidative conditions, according to International Conference on Harmonization guidelines.
Microwave assisted one pot conversion of aromatic aldehydes to nitriles
Authors: Hijji Yousef Mohammad , Rajan Rajeesha , Tabba Hani Darwish , Abu-Yousef Imad Ali , Mansour Said , Yahia Hamdi Ben
Published: September 2018

Nitriles are versatile organic precursors in organic synthesis and have numerous applications. An efficient microwave assisted method for conversion of aromatic aldehydes to the corresponding nitriles is reported. Aldehydes are readily converted to oxime followed by acetylation and acetic acid elimination to provide nitriles in good yields within minutes. The method proved to be efficient for the synthesis of aromatic and heterocyclic nitriles. The reaction proceeds smoothly by microwave at 150 °C for 5 minutes. The obtained products are isolated simply by filtration or extraction.
QSAR and docking studies of α,β-unsaturated carbonyl compounds against human breast adenocarcinoma cell line MCF-7
Authors: Almahdi Maysoon Mohammed , Saeed Ahmed Elsadig Mohamed , Metwally Nadia Hanafy
Published: September 2018

A quantitative structure-activity relationships (QSAR) studies were carried out by correlating activity against human breast adenocarcinoma cell line MCF-7 of series of α,β-unsaturated carbonyl compounds with their physicochemical descriptors using multiple linear regression method. The predictability of the QSAR model was estimated using internal and external predictivity methods. The best QSAR model was selected, having the squared correlation coefficient r2 = 0.84684, correlation coefficient r = 0.9202, standard deviation s = 0.38484, and cross-validated squared correlation coefficient Q2 = 0.7621. Model obtained was used to predicted the activity against breast cancer for a set of designed α,β-unsaturated carbonyl compounds (A1-A16). Docking studies was performed for A1-A16 compounds to evaluated their inhibition on c-Met kinase, which has been overexpressed in a number of cancers.
Graphical Contents
Authors: Arslan Hakan
Published: September 2018

Graphical Contents
Digestive tract morphometry and breast muscle microstructure in spent breeder ducks maintainedin a conservation programme of genetic resources
Authors: Kokoszyński Dariusz , Saleh Mohamed , Bernacki Zenon , Kotowicz Marek , Sobczak Małgorzata , Żochowska-Kujawska Joanna , Stęczny Kamil
Published: September 2018

Abstract. The objective of this study was to compare three genetic groups of ducks: P9 (French Pekin), K2 (bred from wild mallards – Anas platyrhynchos L. and Pekin duck), and KhO1 (hybrid of Khaki Campbell drake and Orpington Fauve duck) after two breeding seasons for body weight and length, length of intestine and its segments, percentage of other internal organs, and breast muscle microstructure. The study used 60 ducks, 20 birds (10 males and 10 females) from each genetic group. At 110 weeks of age, P9 ducks exhibited significantly (p<0.05) greater body weight and length, and length of intestine and its segments (except for colon length) compared to K2 and KhO1 ducks. KhO1 ducks had significantly shorter jejunum and ileum compared to K2 birds. The lighter K2 and KhO1 ducks had significantly greater relative length of intestine and its segments. In P9 ducks, liver, heart, and gizzard were heavier and spleen percentage in body weight significantly lower than in K2 and KhO1 birds. KhO1 ducks had a significantly higher percentage of proventriculus compared to the other duck groups. The different genetic origins of the ducks had no effect on microstructural characteristics of m. pectoralis superficialis except for perimysium and endomysium thickness. Our study provided information about differences in the digestive tract morphometry and breast muscle microstructure of ducks from three genetic groups after two reproductive seasons, which are maintained in a conservation programme of genetic resources in Poland.
An evidence-based method for assessing the value of a search tool: a pilot study
Authors: Pearson Donald Stanley , Roksandic Stevo , Kilanowski Jill
Published: October 2018

Objective: The objective of this study was to develop an evidence-based method with a set of metrics that could be used to assess an information search tool.Methods: This pilot study analyzed a two-group convenience sample of graduate nursing students and resident physicians. The intervention group received ten minutes of instruction on a familiar search tool (eSearcher). Each group was provided one prompt to search for clinical guidelines on a given topic within their scope of practice and asked to find the best result using only eSearcher (intervention group) or specifically excluding eSearcher (comparison group). Three measurements of search results were employed: time elapsed to complete the search, an accuracy score, and a participant-reported score of confidence in the result.Results: Forty-two students participated in this study (23 graduate nursing students and 19 resident physicians). The intervention group consisted of 22 participants (12 graduate nursing students and 10 resident physicians), and the comparison group consisted of 20 participants (11 graduate nursing students and 9 resident physicians). The intervention group had lower mean ranks in both accuracy and confidence compared to the comparison (not eSearcher) group, although these differences were not significant. However, the intervention (eSearcher) group had significantly longer search times compared to the comparison (not eSearcher) group.Discussion: These findings provided new insights into the performance of the search tool and how users felt about their search experience. The quantitative evidence gained from this study led directly to an informed decision to explore other options for search tools. The evidence-based methods and process developed in this pilot study will enable similar studies to test other student groups and other search tools, leading to better informed purchasing and instructional decisions.
Data dreams: planning for the future of historical medical documents
Authors: Dong Lorraine , Ilieva Polina , Medeiros Aimee
Published: October 2018

Historical medical collections with privacy-sensitive information are a potentially rich source of social, behavioral, and economic data for a wide array of researchers. They remain relatively undiscoverable and at risk for destruction, however, because of their restricted content and challenging media formats. Team members from two institutions—the University of California, San Francisco, and the University of Texas at Austin—present their respective initiatives to create digital archives and databases that address the privacy and technological challenges of such collections. In doing so, they also argue for the importance (and feasibility) of medical libraries and archives to take the initiative to preserve and make accessible historical patient data.
Evidentials are syntax-sensitive: The view from Bangla
Authors: Bhadra Diti
Published: October 2018

This paper studies an evidential in Bangla which changes its evidential flavor based on its syntactic position. Forging novel connections with the literature on finiteness, indexical shift, and complementizer agreement, this paper demonstrates how evidentials can be sensitive to the presence of syntactic heads that represent the point-of-view of an utterance. Three main claims are made: (i) evidentials always take finite clauses which are perspective-sensitive, (ii) this perspective-sensitivity is syntactic, i.e. it is the result of control by speech-act heads, (iii) coindexation or contraindexation among these perspectival heads can have very important effects on word order in evidential constructions. This paper thus offers a comprehensive syntactic profile of evidential particles, which have generally been investigated with regard to their semantic-pragmatic contribution, arguing that the structural configurations these elements appear in have undeniably crucial effects on the interpretative component.
A Comparative Study on Medicine Pricing in Brazil, Russia, India, China and South Africa (BRICS)
Authors: Bangalee Varsha , Suleman Fatima
Published: September 2018

BACKGROUND: It is well documented that high prices hinder access to medicines to a large percentage of the population in low- and middle-income countries. It is with this in mind that governments have made attempts to control medicine pricing with the intent to protect and promote a country’s overall health. BRICS as Brazil, Russia, India, China and South Africa have collectively become to be known, represent five newly emerging global economies, each one attempting to control medicine pricing and improve accessibility.

OBJECTIVE: To compare the medicine pricing regulatory efforts made by each of the BRICS countries.

METHOD: This was achieved through the dissemination of an online survey posed to members of the BRICS Medicines Alliance. Questions in the survey looked at the presence of an essential’s medicines list; pricing regulations and control measures employed at the manufacturer, wholesaler and retail level.

RESULTS: The findings reveal that each country has adopted different paths and time frames toward policy and regulatory development.

CONCLUSION: Despite the variations in policy adoption, shared lessons can still be learnt from each country to improve the outcomes for each individual country and create an opportunity for pharmaceutical growth and transparency in medicine pricing.
Body Composition, Chronic Disease Risk and Physical Activity Levels of Urban and Rural Women in Selected Zimbabwean Communities
Authors: Mhlanga Sinikiwe , Sookan Takshita
Published: September 2018

BACKGROUND: Maintaining a physically active lifestyle helps to keep a healthy weight and lowers the risks of chronic diseases. The aim of this study was to determine and compare body composition, chronic disease risk and physical activity levels of rural and urban women in selected Zimbabwean communities.

METHOD: The study followed a descriptive, comparative, and cross sectional design. A sample size of 280 women aged 18 to 60 years volunteered to participate. Anthropometric variables, blood pressure, blood glucose and cholesterol were measured using standard protocols. The International Physical Activity Questionnaire (IPAQ) and a Nutritional Questionnaires were self-administered. Routine descriptive statistics, independent t-tests and Chi-square tests were used and the significance was set at p≤0.05.

RESULTS: A significant difference between urban and rural women with regards to Body Mass Index (BMI) p=0.009 (mean difference 1.62; 95% CI), Waist-Hip Ratio (WHR) p=0.003 (mean difference 0.02; 95%CI) was noted. Regarding chronic disease risk, urban women were classified as high and very high risk compared to rural women, p=0.019. With regard to the IPAQ there were significant differences in the transport domain, p=0.046, domestic domain p=0.02 and leisure domain p=0.020 between urban and rural women.

CONCLUSION: The study indicated an increase in prevalence of overweight and obesity with increased chronic disease risk in urban women compared to rural women. Both urban and rural women showed high levels of physical activity.
Reviewer Acknowledgements for Journal of Educational and Developmental Psychology, Vol. 8, No. 2
Authors: Wong Carol
Published: September 2018

Reviewer Acknowledgements for Journal of Educational and Developmental Psychology, Vol. 8, No. 2, 2018.
LEGAL INSTRUMENTS OF FAMILY POLICY ON THE EXAMPLE OF A PROVISION INTRODUCED IN CONNECTION WITH THE GOVERNMENTAL PROGRAM „FAMILY 500+” IN THE RURAL VILLAGE OF LELÓW
Authors: Podgórska-Rykała Joanna , Zasuń Aneta
Published: October 2018

The aim of the considerations is to assess the assumptions of the nearly 2-year government program “Family 500+” based on the example of the rural village of Lelów. Considerations are based on empirical data (including: interview, questionnaire and docu¬ment analysis), in the context of the original assumptions of the program creators. The rese¬arch part of the article was placed in a small rural village, located in the Silesia region. The provision “Family 500+” that is being discussed is functioning from April 1, 2016 and alre¬ady with the idea of its establishment a lot of controversy arose. The authors are looking for the answers to the question of who is the main beneficiary of support, whether it goes to the most needy families or not, and what are short-term, and what can be the long-term effects of the implemented solution? Are they in line with the political expectations of the program and its purpose, or do they lead to the consolidation of negative trends in the labor market?
AROUND THE ISSUES OF INFORMATION SECURITY
Authors: Fleszer Dorota
Published: October 2018

It is undeniable that processing of personal data is an inherent element of the relationship between an employer and an employee. The employee cannot maintain information autonomy in this social sphere, however it shall not mean the employer’s freedom in obtaining and collecting any information about the employee. Provisions of the Labour Code specify how to protect the employee against excessive requirements made by employers.
News from the Field
Authors: Free David
Published: October 2018

UCLA Library to host digital archive of ancient Arabic and Syriac manuscriptsACRL OpenCon scholarship recipientsMellon Fellowships for Dissertation Research in Original Sources applicationsProQuest News discoverable in Ex Libris PrimoEBSCO releases OnArchitecture video libraryLibrary of Congress launches North Korean Serials Database
Building a curriculum materials center from the ground up: A practical approach
Authors: Hoffman Renee L.
Published: October 2018

While many large universities boast ample space and hefty budgets for their curriculum materials centers, as a small university with a tight budget, creating Saint Francis University’s (SFU) Curriculum Materials Center (CMC) was a process that required creativity, planning, and ingenuity. This article outlines that process. SFU, located in rural Loretto, Pennsylvania, is a small, Catholic university with an FTE of approximately 2,400.
Dystonia: A Leading Neurological Movement Disorder
Authors: Kabir Md. Tanvir , Yasmin Hasina , Khanam Umme Salma , Jamiruddin Mohd. Raeed , Uddin Md. Sahab , Abdel-Daim Mohamed M.
Published: October 2018

Dystonia is the third leading movement disorder arising mainly from the damage of basal ganglia or other parts of the brain that control movements. The objective of this review is to represent the detailed profile of dystonia. A computerized literature review was conducted in authentic scientific databases including PubMed, Google Scholar, Scopus, Science Direct and National Institutes of Health (NIH) etc. Terms searched included dystonia, risk factors, etiologies, clinical features, classification, pathology, guidelines, treatment strategies, primary and secondary dystonia. Initially, 97 articles and 9 books were extracted but finally, 64 articles and 7 books were used. After analysis, we found that causes of dystonia could be acquired or inherited and dystonia can be classified based on age at onset, etiology, and distribution of the affected body parts. The risk factors of this heterogeneous disorder could be trauma, thyroid disorder, hypertension, life habits, occupation, use of drugs and genetics. A significant number of articles were found which signify the ability of brainstem and cerebellar pathology to trigger the symptoms of dystonia. Since antipsychotic drugs are the most commonly prescribed among the people with intellectual disability (ID), therefore they possess a greater risk to experience antipsychotic drugs-induced movement side effects including acute dystonia, parkinsonism, tardive dyskinesia, and akathisia. Depending on various manifestations and causes, there are several treatment options including oral medications, intramuscular injection of botulinum toxin, neurosurgical procedures and occupational therapy.
Experimental Study on Family Formation and Moral Values of Students
Authors: Absatova Marfuga Absatovna , Nishanbaeva Sabira , Nurpeisova Toleuzhan Baibolovna , Atemova Kalipa Tursunovna
Published: October 2018

The relevance of the research topic is due to the diversity and complexity of the tasks of human education in the 21st century. The modernization processes taking place in the modern Kazakhstani society created a deep crisis of many aspects of social life, including negatively affecting the value orientations of the younger generation, led to the devaluation of family values, alienation of youth from institutions of upbringing. This significant transformation partly led to a change in the orientations and priorities in the educational process of students.
Analysis of the activity of higher education institutions in the education of family and moral values among students in the process of teaching and educational work made it possible to identify contradictions between:
- the acute need of modern society for the upbringing of family and moral values among students and the underestimation of the significance of the process of family education in general;
- the existing traditionally developed approach to determining the content of forms and methods of instruction and the objective needs of a qualitatively new attitude to the education of family and moral values among students in the process of education and educational work.
This study allowed us to draw the following conclusions. The essence of the concept of "value" was substantiated, the content of the concept "family and moral values" was clarified on the basis of the analysis of scientific psychological and pedagogical literature. Experimental work was carried out among students of 1,2,3 courses of the specialty "Pedagogy and Psychology" of the Kazakh National Pedagogical University named after Abay, within the framework of which they tried to determine whether the family value is significant in the student environment.
Justification of the novelty of the work. The authors attempted to reveal for the first time among students of a pedagogical university their real relation to the family, to family and moral values.
Theoretical and Methodological Enhancement of Managerial Activity in the Teachers’ Professional Motivation Formation of Future Specialists
Authors: Anesova Albina Zhenisovna , Akhmejanov Assad Bisengazievich , Toleubekova Rymshash Kameshovna , Zhumataeva Engilika
Published: October 2018

This article is devoted to the problem of the enhancement of the managerial competence required by rectors of higher education institutions in the Republic of Kazakhstan. The essence of this competence reveals, by its component composition (the strategic, communicative, organizational, psychological, pedagogical, entrepreneurial, and political sub-competencies) is determined and justified. As a practical mechanism for the managerial competence enhancement, it proposes to use the profession-oriented educational technology based on the humanistic and competence-based approaches within the framework of the stochastic scientific paradigm. It notes that this educational technology complies with the modern philosophy of education called “lifelong learning”.
The Foreign Language Students’ Beliefs Regarding Learning Strategies In Different Kazakhstan University Students
Authors: Orynbek Gulnar , Dauletali Akbarkan , Farida Orazakynkyzy , Lyailya Koishigulova , Zhanat Bissenbayeva
Published: October 2018

As we live in global village, there are several inner circle native English speakers around the world. Furthermore, there are people who live in out circle and speak English as a second language, the rest who live in expending circle and use English as a foreign language. The increase use of English as an international language more people believe that the necessity of some knowledge about English language should be known, since it provides the awareness of learners beliefs about English language learning as well as it expands the job opportunities. This study can be significant in two parts (theoretical and practical). Firstly in theoretical part this research can be a new area in English language learners’ beliefs in applied linguistics worldwide, and this study can offers information about Kazakhstan University students’ beliefs about English language learning. Secondly in practical level, this research would help EFL teachers in Kazakhstan for understanding of their students’ beliefs about English language learning, and also can be a guideline to the teachers in their teaching methods as well as for the learners understanding of their own beliefs about English language learning.
Mechanisms on Improving the Education System Quality in the Republic of Kazakhstan
Authors: Lyazat Izteleuova , Takhi Mukhamedeyev , Irina Mukhamedeyeva , Kuandyk Bekishev , Venera Yenseyeva , Saira Rakhipova
Published: October 2018

The article presents the analysis of the components of monitoring as one of management tools for the higher education (HE) system at macro- and micro-levels. The aim of the article is to identify problems of its organization and implementation in the system of professional education on the whole and in higher educational institutions in particular, as well as to analyze the application prospects of monitoring. The conducted research has revealed that although monitoring techniques have been used in the education system widely and for a long time, insufficient account has been taken of opportunities emerging from their direct impact on the effectiveness of education quality. In using monitoring as a tool for assessing higher education quality, various problems arise. Monitoring, in this case, is not a universal tool; but if it is adequate to the existing conditions and its results are correctly used, it can essentially improve the quality of the education process and of its outcomes.
ИНСТАНТ ИНФОРМАЦИЈЕ, ИНСТАНТ ПРИЈАТЕЉИ И ВИРАЛНА СТВАРНОСТ
Authors: Бјелић Анђа , Смиљанић Илија
Published: October 2018

Некада је била књига над књигама, данас је актуелна мрежанад мрежама – Интернет. Фејсбук, Твитер, Инстаграм, Линкидин, Гугл +,Јутјуб и слични сервиси, постали су глобална појава а свет претворили углобално село. Брзина преношења информација и брисање географскихбаријера, као и стварање окружења у коме се сами себи највишедопадамо, допринела је њиховом наглом ширењу. Зато су друштенемреже најидеалнији медиј за комуникацију, забаву али и употребу излоупотребу информација. Није свака информација валидна и не дајеквантитет увек квалитет.Библиотеке као ризница свеколиког знања унапређују своје пословање ипутем друштвених мрежа. Садржаји које она постује морају бити у складуса њеном мисијом. Визуелне сензације које нуди Интернет свакакоостављају јак утисак али трајно памћење даје само прави извор ‒ књига.Пропаганда да је Интернет доступан свима је само делимично тачна. Даби увек били у фокусу најновијих дешавања морате имати одговарајућукомуникациону опрему, која се непрекидно усавршава а то значи да јенепрекидно морате обнављати (што баш није згодно) и непрекидно сеусавршавати у примени нових алата (што је добро). Ослањање само наједан вид информација је недовољно. Први због површности (осимпроверених научних информација), а други због спорости. Брзина јеимператив новог доба. Зато је проток информација у реалном временудопринео да друштвене мреже постану четврта најучесталија активностинтернет корисника. Све то заједно довело је до епидемије виралности.Виралан пост је најновији идеал интернет корисника.
СТРУЧНИ КАТАЛОГ БИБЛИОТЕКЕ ГРАДА БЕОГРАДА У СЛУЖБИ ЊЕНИХ КОРИСНИКА
Authors: Тасић Радмила
Published: October 2018

Савремене библиотеке представљају институције од посебногдруштвеног значаја које активно партиципирају у социјалном животусвих чланова друштвене заједнице. Корисници библиотека, као члановите заједнице, у сталној потрази за информацијама, користе online каталогБиблиотеке града Београда који ради у систему БИСИС. Библиотечкоинформациони систем БИСИС је софтверски систем чији почеци сежу до1992/93. године. Настао је у оквиру пројекта за развој библиотечкемреже Србије да би се касније наставило са радом на Природно-математичком факултету у Новом Саду, као помоћ библиотекарима уприкупљању, индексирању и проналажењу информација садржаних уметаподацима фонда библиотеке.Циљ рада је, поред приказа корисничког претраживања у системуБИСИС у Библиотеци града Београда, и покушај приближавања овогпрограма корисницима из угла библиотекара који раде на обради грађе.Претраживање библиотечког фонда БГБ могуће је на више језика.Такође, корисник бира неки од понуђених начина претраживања: поаутору, по наслову, по кључним речима или напредно претраживање.Могуће је поставити једноставне упите односно претраживати по једномпрефиксу (аутору, наслову) или сложеније упите који сужавају претрагукомбиновањем неколико префикса (аутор и наслов, наслов ипреводилац, аутор и издавач, УДК индекс и кључна реч, ...)У раду су, такође, илустративно представљени графички приказикорисничког интерфејса на различите захтеве.
Scale and confinement phase transitions in scale invariant SU(N) scalar gauge theory
Authors: Kubo Jisuke , Yamada Masatoshi
Published: October 2018

Abstract

We consider scalegenesis, spontaneous scale symmetry breaking, by the scalar-bilinear condensation in SU(N) scalar gauge theory. In an effective field theory approach to the scalar-bilinear condensation at finite temperature, we include the Polyakov loop to take into account the confinement effect. The theory with N = 3, 4, 5 and 6 is investigated, and we find that in all these cases the scale phase transition is a first-order phase transition. We also calculate the latent heat at and slightly below the critical temperature. Comparing the results with those obtained without the Polyakov loop effect, we find that the Polyakov effect can considerably increase the latent heat in some cases, which would mean a large increase in the energy density of the gravitational waves background, if it were produced by the scale phase transition.
Planctomyceten–außergewöhnlich, aber bakteriell: ein Paradigmenwechsel
Authors: Wiegand Sandra , Jogler Christian
Published: October 2018

Amongst the kingdom bacteria, the phylum Planctomycetes is most conspicuous. Planctomycetes seemed to lack the universal bacterial peptidoglycan cell wall, while their cytosol appeared compartmentalized, including a nucleus-like structure. Thus, Planctomycetes were seen as ‘missing link’ between pro- and eukaryotes. However, with the advent of genetic tools for this phylum, recent results led to a paradigm shift: Planctomycetes are the most exceptional bacteria, but bacteria after all.
The Income Elasticity of Global Values of a Statistical Life: Stated Preference Evidence
Authors: Masterman Clayton J. , Viscusi W. Kip
Published: October 2018

Examination of estimates of the income elasticity of the value of a statistical life based on international stated preference studies yields an average between 0.94 and 1.05 overall and 0.65 and 0.80 after controlling for covariates. Quantile regression estimates indicate that the income elasticity is about 0.55 for more affluent countries and 1.0 for lower income nations, i.e., those countries that have estimates of the value of a statistical life below $2 million or per capita income levels below $3212. The estimates distinguish the values of the income elasticity across country either by income level or by the value of a statistical life. These elasticities are similar to those found in revealed preference labor market studies. The estimates are robust, controlling for possible sample selection bias and the influence of covariates, such as the type of risk.
That latent sense of otherness: old and new anti-semitisms in postwar Italy
Authors: Lichtner Giacomo
Published: October 2018

This article traces the evolution of anti-semitism in post-war Italy, from the early responses to the Holocaust to the increasingly concerning signs of contemporary anti-Jewish prejudice. Tracing the discourses of religious and secular attitudes towards Jews, the piece shows how resilient certain stereotypes are, and how assumptions about citizenship continue to undermine the respect of difference in Italy. With a reflection that is meant to be personal and scholarly at the same time, this contribution has the aim of facilitating a broader reflection, that spans instances of anti-semitism among the anti-racist Left, the correlation between unresolved anti-Jewish prejudice and widespread racist, anti-immigrant discourses, the challenges of a politicised memorialisation of the Holocaust, and also the role Jewish communities may play in this unsettling context.
THE PRODUCTION OF POLYPHONIC MANUSCRIPTS IN THIRTEENTH-CENTURY PARIS: NEW EVIDENCE FOR STANDARDISED PROCEDURES
Authors: Bevilacqua Gregorio , Catalunya David , Torres Nuria
Published: October 2018

Modern understanding of the production and dissemination of thirteenth-century polyphony is constrained by the paucity of manuscript sources that have been preserved in their entirety; the panorama of sources of medieval polyphony is essentially fragmentary. Some of the surviving fragments, however, were torn from lost books of polyphony that were to some extent comparable to well-known extant codices. The fragment of polyphony preserved in the binding of manuscript 6528 of the Biblioteca Nacional de Madrid is illustrative in this respect. This fragment displays a number of codicological and musical features that are strikingly similar to those of the Florence manuscript (F). Both sources share format and mise-en-page, make use of similar styles of script, notation and pen-work decoration, transmit the pieces in the same order, and present virtually identical musical readings. The Madrid fragment thus provides new evidence for a standardised production of polyphonic books in thirteenth-century Paris. The study provides a detailed account of the fragment’s codicological and philological features, and explores the hypothesis that it originated in the same Parisian workshop that produced F.
Automated Indices of Clustering and Switching of Semantic Verbal Fluency in Parkinson’s Disease
Authors: Farzanfar Delaram , Statucka Marta , Cohn Melanie
Published: October 2018

Objectives: Deficits in semantic verbal fluency (SVF) can stem from dysfunction of an executive control system and/or of semantic knowledge. Previous analyses of SVF responses were devised to characterize these two components including switching and mean cluster size (MCS) indices, but these rely on subjective experimenter-based assessment of the words’ relatedness. To address this limitation, computational data-driven SVF indices have been developed. Our aim is to assess the validity and usefulness of these automated indices in the context of cognitive decline in Parkinson’s disease (PD). Methods: This is a retrospective study including 50 advanced PD patients with (n=28) or without (n=22) mild cognitive impairment (PD-MCI). We analyzed animal SVF outputs using an automated computational approach yielding switching, MCS, and cumulative relatedness (CuRel) indices. We compared these indices to the classic experimenter-based switching and MCS indices to assess concurrent validity, and against neuropsychological measures of executive functioning and semantic knowledge to assess construct validity. We also examined whether these indices were impaired and predicted PD-MCI. Results: Automated switching indices, but not MCS or CuRel, showed evidence of concurrent and construct validity, and characterized individual difference in advanced PD. Automated switching indices also outperformed the experimenter-dependent index in predicting the presence of PD-MCI. Conclusion: Computational methods hold promise as fine-grained, unbiased indices reflecting the executive component of SVF, but none of the methods provided valid measures of semantic knowledge in PD. Our data also confirm that SVF are not adequate tests of semantic memory in patients with executive dysfunction such as PD. (JINS, 2018, 24, 1047–1056)
Pure theory and progressive liberalism: Frank Fetter and the Austrian economists
Authors: McCaffrey Matthew
Published: October 2018

Frank A. Fetter is often classified as an American representative of the Austrian school, yet surprisingly, there is practically no published record of his views of the Austrians or theirs of him, and there is no indication that he ever seriously interacted with them after the First World War. However, Fetter enjoyed many personal and professional relationships with the Austrians, and they shared a reciprocal influence on each other's ideas that deeply influenced their respective research programs. This paper draws on unpublished archival records to explore Fetter's unique place in the history of economics, in particular, his positive and negative interactions with the leading individuals and institutions of the Austrian school. Their half-century of influence sheds light on Fetter and his role in American economics, but also brings to light a wide range of information about the lives, works, and personal relations of the Austrians that have not been included in their biographies or institutional histories.
A Cross-Sectoral Approach to Tackle Ocean Plastic Pollution
Authors: Waluda C. , Cavanagh R. , Manno C.
Published: October 2018

Plastic in the Oceans: Challenges and Solutions; Cambridge, United Kingdom, 7 March 2018
Genome analyses of uncultured TG2/ZB3 bacteria in ‘Margulisbacteria’ specifically attached to ectosymbiotic spirochetes of protists in the termite gut
Authors: Utami Yuniar Devi , Kuwahara Hirokazu , Igai Katsura , Murakami Takumi , Sugaya Kaito , Morikawa Takahiro , Nagura Yuichi , Yuki Masahiro , Deevong Pinsurang , Inoue Tetsushi , Kihara Kumiko , Lo Nathan , Yamada Akinori , Ohkuma Moriya , Hongoh Yuichi
Published: October 2018

We investigated the phylogenetic diversity, localisation and metabolism of an uncultured bacterial clade, Termite Group 2 (TG2), or ZB3, in the termite gut, which belongs to the candidate phylum ‘Margulisbacteria’. We performed 16S rRNA amplicon sequencing analysis and detected TG2/ZB3 sequences in 40 out of 72 termite and cockroach species, which exclusively constituted a monophyletic cluster in the TG2/ZB3 clade. Fluorescence in situ hybridisation analysis in lower termites revealed that these bacteria are specifically attached to ectosymbiotic spirochetes of oxymonad gut protists. Draft genomes of four TG2/ZB3 phylotypes from a small number of bacterial cells were reconstructed, and functional genome analysis suggested that these bacteria hydrolyse and ferment cellulose/cellobiose to H2, CO2, acetate and ethanol. We also assembled a draft genome for a partner Treponema spirochete and found that it encoded genes for reductive acetogenesis from H2 and CO2. We hypothesise that the TG2/ZB3 bacteria we report here are commensal or mutualistic symbionts of the spirochetes, exploiting the spirochetes as H2 sinks. For these bacteria, we propose a novel genus, ‘Candidatus Termititenax’, which represents a hitherto uncharacterised class-level clade in ‘Margulisbacteria’. Our findings add another layer, i.e., cellular association between bacteria, to the multi-layered symbiotic system in the termite gut.