bluuebunny/crossref_metadata_2025 huggingface dataset:
Early Short Segment Pedicle Screw Fixation Including Fractured Vertebra of Thoracolumbar Burst Fracture with Incomplete Spinal Cord Injury
Authors: Islam Mohammad Aminul , Shahnewas, Shahnewas, , Alam Muhammad Monjur-ul-
Published: December 2023

Background: Fractures of the thoracolumbar region are the most common injuries of the vertebral column; among them burst fractures are the most frequent. Several studies were done to see the surgical outcome of thoracolumbar burst fracture hence surgery was recommended for a better outcome. So, the current study aimed to evaluate the clinical, functional, and radiological outcome of short-segment pedicle screw fixation including the fractured vertebral body. Objectives: The primary aim of this study is to comprehensively evaluate the functional and radiological outcomes of early short-segment pedicle screw fixation, particularly in cases involving fractured vertebrae in thoracolumbar burst fractures accompanied by incomplete spinal cord injuries. Materials & Method: In this prospective observational study, 31 cases were included between April 2017 and July 2018 through non-randomized purposive sampling. All patients, aged 15 to 60 years, underwent posterior decompression and short-segment pedicle screw fixation, including the fractured vertebral body, within 21 days of the fracture. Postoperative functional outcomes were clinically assessed using the Oswestry Disability Index (ODI), Visual Analog Scale (VAS), American Spinal Injury Association (ASIA) scale, Denis Work Scale, and radiologically evaluated by Cobb's kyphotic angle, kyphotic deformation, Beck index, and Bridwell criteria. Postoperative follow-ups were conducted at the 6th, 12th, and 24th weeks. Results: In this study, 31 cervical spinal injury patients underwent operative treatment with a 3 to 12-month follow-up. Most were day laborers (35.48%), experiencing falls from height (80.65%), mainly at L1 (54.84%). Initial ASIA grade D improved to E (54.58%). Postoperatively, significant improvements in kyphotic angles, Beck index, and vertebral height were noted, with some correction loss at the final follow-up. Complications occurred in 22.58% of cases, including per-operative hemorrhage, dural tear, .......
Evaluation Outcomes and Complications of Temporary Suture Tarsorrhaphy (TST) in Cases of Impending Corneal Ulcer Perforation
Authors: Hoque Kazi Nasimul
Published: December 2023

Introduction: A corneal ulcer, a defect of the corneal epithelium involving the underlying stroma, is a potentially vision-threatening ocular emergency. Even with prompt treatment patients can suffer significant morbidity with complications including corneal scarring or perforation, development of glaucoma, cataracts or anterior and posterior synechiae, and vision loss. Objective: to evaluate outcomes and complications of temporary suture tarsorrhaphy (TST) in cases of impending corneal ulcer perforation. Methods: In this retrospective study was carried out at Department of Ophthalmology, Ad-din Akij Medical College, Khulna and Eye Hospital, Khulna, Bangladesh from January to June 2022. All cases of fungal keratitis that had undergone TST after evaluation were included. Patients with a minimum follow up of 3-month post tarsorrhaphy were included in the study. Information reviewed included patient age and sex, visual acuity (VA) at presentation, size and location of the ulcer, indication for TST, duration of signs and symptoms before TST, time to epithelial healing after TST, complications associated with non-healing corneal ulcer, complications of TST, number of TST needed and the duration of follow up. Results: During the 12 months study period, 300 cases were planned for TST out of which 90 patients (30.0%) fulfilling the inclusion and exclusion criteria were included for the study. There were not any cases of both eye involvement. Mean age of the patients in this study was 50.34+ 14.56 years (range 20—85 years) with a male-to-female ratio of 2.22:1. Only 3 patients (2.52%) had a VA of more than 6/60, 31 patients (34.44%) had VA between 6/60 to counting finger-close to face (CF-CF) and 57(63.33%) had hand movement (HM) to perception of light (PL) at first visit. The patients presented to the cornea service 3 to 45 days (mean 19.34+10.62 days) after the onset of symptoms, with only 7.57% of the patients presenting within 1 week. Out of 90 patients, 64 patients ....
A Root-Supported Overdenture: An Approach to Preventive Prosthodontics
Authors: Wafa Mami , Nihel Charfi , Wadii Bembli , Rim Bibi , Nadia Frih
Published: December 2023

The use of residual teeth to support an attachment-retained overdenture is an alternative therapy to extractions and complete removable denture, particularly for the mandibular arch. Overdenture offers several advantages, including maintenance of the alveolar ridge and proprioception. Retention and stability are also enhanced by means of attachment systems, which improves schwing efficiency and better psychological integration of the prosthesis. This article describes, through a clinical case, the fabrication and interest of a tooth-supported overdenture using two axial attachments.
Plexiform Neurofibroma: Case Report
Authors: Opango ADC. , Hadri H. El , Fettal F. , Mourabit F. , Aziz Z. , Hattab N. Mansouri
Published: December 2023

Plexiform neurofibroma (PNF) is a benign nerve tumor, most often developing in the cephalic region. It is usually considered pathognomonic for neurofibromatosis type 1 (NF1) or Von Recklinghausen disease. We report the case of a patient treated in our training for plexiform neurofibroma on NF1. This is a 28-year-old patient, without any particular ATCD, who consulted for a left scalpo-fronto-palpebral subcutaneous swelling that had been present for 12 years, causing major aesthetic discomfort. Furthermore, it presented numerous (> 6) café au lait spots greater than 15mm in diameter. The patient underwent excision of the left scalpo-fronto-palpebral tumor under general anesthesia with direct closure. The pathological examination confirmed the diagnosis of plexiform neurofibroma. The postoperative course was simple and the result satisfactory. Surgical excision remains the only treatment for plexiform neurofibomas in Von Recklinghausen disease.
A Rare Combination of Mechanical Complications Following Myocardial Infarction: Ventricular Septal Rupture and an Extensive Ventricular Aneurysm
Authors: Beladel Wassim , Minaoui Mohamed El
Published: December 2023

Mechanical complications following acute myocardial infarction (MI) are rare and account for <1% of the total cases, with the advent of the newest revascularization methods. Although this low incidence, the mortality rate is high, especially among older patients. A 51 years old female, with a history of diabetes and asthma, was admitted to our cardiac intensive care unit for heart failure symptoms. She was diagnosed about 3 weeks ago, with acute anterior wall MI. She did not undergo any revascularization because of the lack of means and was on optimal medical therapy. Transthoracic echocardiography (TTE) revealed akinesia of the inferior, septal, and lateral wall, and all apical segments with a giant aneurysm of 10mm, and a posterior interventricular rupture with a left-right shunt, with a reduced left ventricular (LV) ejection fraction of 19%. An enhanced computed tomography (CT) scan revealed a ventricular septal (VS) defect with a giant left ventricular aneurysm (LVA), which was connected to the LV posterior wall. Urgent cardiac surgery after a percutaneous cardiac intervention was not realized because of lack of means. The association of VS rupture and LVA, found in our patient, is an extremely rare and highly lethal complication requiring urgent surgical management. Its incidence is between 1% and 2% of MIs. TTE has very high sensitivity and specificity, to provide diagnosis and evaluation of VS rupture and LVA. Color-flow Doppler identifies abnormal flow within the aneurysm and helps to highlight ventricular ruptures as an additional image in the endocardium. CT is fast, provides a clear resolution of the LV, and may be used to demonstrate the complications of infarction. The management of VSD is surgical, with the difficulty of repair from fragile infarcted tissue. Medical therapy should stabilize the hemodynamics and act as a bridge to surgery. The simultaneous presence of a VS rupture and LVA is rare and usually occurs within the MI. However, as shown in ..
Atypical Intralymphatic T-Cell Proliferation during DRESS Mimicking Intravascular Lymphoma: Case Report
Authors: Elouarith Ihssan , Jahid Ahmed , Zouaidia Fouad , Loubaris Zineb , Senouci Karima , Bernoussi Zakia , Znati Kaoutar
Published: December 2023

Drug-induced hypersensitivity syndrome or drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe drug-induced reaction that represents a life-threatening condition. The histopathologic appearance of the skin biopsy is nonspecific but may exceptionally show an atypical intralymphatic lymphocytic infiltrate, and mimic an intravascular lymphoma. Through this article, we will report an exceptional case of a patient presenting with skin lesions pointing to a dress, but whose histological appearance, in the presence of adenopathy during physical examination, can lead, by mistake, to the diagnosis of an intralymphatic lymphoma. We aim to highlight the various diagnostic indices allowing the distinction between these two entities, including the immunohistochemical study, the search for the TcR clonal rearrangement and the anatomo-clinical correlation.
Estimation of the Xrama Distribution Parameter Under Complete and Progressive Type-II Censored Schemes
Authors: Etaga Harrison O. , Onyekwere Chrisogonus K. , Lydia Omeje Ifunanya , Nwankwo Mmesoma P. , Oramulu Dorathy O. , Obulezi Okechukwu J.
Published: December 2023

In this paper, a two-component mixture of Exponential and Rama distribution named Xrama distribution is introduced and discussed. The distributional properties such as moment and the related measures including other characteristics namely quantile function, mean residual life function, Bonferroni curve, Lorenz curve, order statistics, stochastic ordering, and entropy were derived. Simulation study for both complete and progressive type-2 censored schemes is used to illustrate and analyze the behavior of the model. The proposed model’s performance is assessed through a comparison with various other lifetime distributions using negative log-likelihood, Akaike Information Criterion, Corrected Akaike Information Criterion, Bayesian Information Criterion, and Hannan–Quinn information criterion on an actual dataset. The results reveal that, when modeling real lifetime data, the suggested model exhibits greater flexibility than the competing models examined in this study.
Uji aktivitas antioksidan dan evaluasi fisik sediaan emulgel kombinasi ektraks daun kelor dan ekstrak daun karamunting
Authors: Gunawan Adhi , Fatmawati Annisa , Solikhah Wahyu Yuliana , Putri Nafa Meilingga , Hotimah Baiq Husnul
Published: December 2023

Kosmetik untuk perawatan kulit banyak memanfaatkan antioksidan sebagai zat aktif dalam sediaanya, antioksidan mampu mencegah terbentuknya suatu radikal bebas yang baru, menetralisir dan menghindari efek samping sehingga memperlambat proses penuaan dan kerusakan pada kulit.. Emulgel merupakan sediaan topikal yang mempunyai beberapa keunggulan antara lain sifat thiksotropik, tidak berlemak, diaplikasikan mudah, bersih, lembut, mudah dibersihkan, penyimpanan lebih lama, nyaman saat digunakan dan transparan. Penelitian ini bertujuan untuk membuat campuran ekstrak daun Kelor (Moringa oleifera Lam) dan ekstrak daun Karamunting (Melastoma malabathricum L.) sebagai emulsi serta mengetahui aktivitas antioksidan dengan metode DPPH. Basis emulgel yang digunakan adalah Karbopol berfungsi sebagai gelling agent dan kombinasi ekstrak daun Kelor dan daun Karamunting dengan variasi konsentrasi (25%: 75%, 50% : 50%, 75% : 25%). Hasil penelitian menunjukan sediaan emulgel kombinasi ekstrak daun Kelor dan Ektrak daun Karamunting memenuhi seluruh standar uji fisik sediaan, dan dari hasil uji aktivitas antioksidan menyatakan formula I memiliki aktivitias antioksidan paling tinggi dengan nilai IC50 40, 07 ppm termasuk dalam Antioksidan sangat kuat.
AVANÇOS NA ANESTESIA PARA CIRURGIAS CARDÍACAS PEDIÁTRICAS, UMA OVERVIEW.
Authors: Silva Nathalia Marques , Souza Luan Moraes , Zanetti Ianna Gazolla , Neves Ana Luiza , Ferreira Franciane Mara Rezende , Medes Rebeca Zanchetta , Gatti Amanda Botte , Mangilli Gabriela Cassiano , Lima Lucas Rodrigues Castilho de
Published: December 2023

Introdução: Este estudo propõe uma revisão abrangente dos avanços na anestesia para cirurgias cardíacas pediátricas, explorando práticas recentes e contribuições significativas para o campo. A atenção específica é dada a técnicas anestésicas, complicações perioperatórias e desfechos clínicos relevantes. Métodos: Realizamos uma revisão sistemática da literatura, abrangendo os últimos 20 anos, com base em publicações encontradas nas bases de dados PubMed, SCIELO e Biblioteca Virtual em Saúde (BVS). A estratégia de busca utilizou descritores DeCS, incluindo "Anestesia Pediátrica", "Cirurgia Cardíaca Pediátrica" e "Manejo Anestésico em Cardiopatias Congênitas". Foram incluídos estudos originais, revisões sistemáticas e ensaios clínicos randomizados que abordaram diretamente práticas anestésicas e resultados perioperatórios em cirurgias cardíacas pediátricas. Resultados: A análise dos estudos revelou insights valiosos sobre a extubação precoce, impacto das técnicas anestésicas nos níveis séricos de troponina, paradas cardíacas relacionadas à anestesia, manejo de pacientes cardiopatas pediátricos em cirurgias não cardíacas, e efeitos da extubação precoce pós-cirurgia cardíaca infantil. Além disso, considerações sobre o uso da dexmedetomidina, recrutamento alveolar e insucesso no desmame ventilatório enriqueceram a análise. Conclusão: Destaca-se a diversidade de avanços na anestesia para cirurgias cardíacas pediátricas, fornecendo uma visão holística das práticas contemporâneas. A análise crítica dos resultados sugere tendências promissoras, identifica áreas para aprimoramento e destaca a importância contínua da pesquisa para otimizar a segurança e eficácia desses procedimentos cruciais em pacientes pediátricos.
REABILITAÇÃO PERINEAL E O BIOFEEDBACK: A TRANSFORMAÇÃO DE ESTÍMULOS MECÂNICOS NAS RESPOSTAS SEXUAIS SOB A ÓTICA FISIOTERAPÊUTICA
Authors: Barroncas Giovanna Nascimento , Queiroz Ilkenison Pinheiro , Livramento Rosileide Alves
Published: December 2023

Introdução: Disfunção sexual é caracterizada como toda situação em que a mulher não consiga realizar relação sexual, independente do estágio da atividade (desejo, excitação ou orgasmo). O fortalecimento dos músculos pélvicos resulta em melhora das contrações voluntárias e o tratamento com Bioffedback pode alcançar melhor prognóstico, através de estímulos visuais e sonoros, aumentando nível de força e consequente melhora da função sexual e qualidade de vida. Objetivo: Analisar se o biofeedback possui propriedades que reabilite pacientes com disfunções sexuais, transformando estímulos mecânicos, em recrutamento de fibra muscular do assoalho pélvico e conscientização perineal. Metodologia: Pesquisa de revisão bibliográfica integrativa, utilizando artigos publicados no período de 2013 a 2022, nos idiomas português e inglês, pesquisados nas plataformas PubMed, SciElo, LILACS e Medline. Resultados: O tratamento com o Biofeedback, apresenta o ganho de consciência dos músculos do assoalho pélvico e seu fortalecimento, além de auxiliar na função sexual e consequente melhora na qualidade de vida.
DESAFIOS NA ATENÇÃO BÁSICA À SAÚDE NO BRASIL: ENFOQUE NA SAÚDE PÚBLICA
Authors: Silva Ana Paula Stefanelo e , Silva Édla Édna da , Júnior Oscar Vaz Pedroso , Ramos Vivian de Brito Formiga , Santos Camila Gomes dos , Bezerra Laysla de Arruda Fontenele , Fachini Mérlim , Gurgel Hortência Ferreira , Carvalho Laura Stefanny Gomes de , Oliveira Gerson Pedroso de , Souza Ilzani Reis da Silva Marcondes de , Barbosa Milton Jorge Lobo
Published: December 2023

Introdução: Um dos principais desafios enfrentados na atenção básica à saúde no Brasil é a desigualdade regional, que impacta a distribuição de recursos e a qualidade dos serviços oferecidos à população. Objetivo: Analisar e identificar soluções viáveis para superar os desafios na saúde pública e melhorar a qualidade dos serviços oferecidos à população.  Metodologia: Realizou-se uma revisão integrativa da literatura, mediante um levantamento bibliográfico nas bases de dados científicas: LILACS, PUBMED e SCIELO.  Resultados e Discussões: A discussão entre os autores sugere que a superação dos desafios na saúde pública requer uma abordagem multifacetada. A inclusão de políticas sensíveis à diversidade, a gestão eficiente do SUS, a inovação na APS e a promoção do diálogo ativo entre profissionais de saúde e comunidade emergem como elementos essenciais para a melhoria da qualidade dos serviços oferecidos à população. Conclusão: Em conclusão, a análise dos artigos selecionados destaca a complexidade dos desafios enfrentados pela saúde pública no Brasil e a necessidade urgente de ações coordenadas para superá-los. A diversidade de temas abordados, desde a acessibilidade de grupos específicos, como os transexuais, até as questões mais amplas relacionadas à regulação do SUS, evidencia a multiplicidade de fatores que afetam a eficácia do sistema de saúde.
Uso de diferentes substratos orgânicos no crescimento e desenvolvimento inicial do agrião da terra (Barbarea verna)
Authors: De Jesus Souza Maria Milena , Silva Esmeraldo Dias da , Passos Noedson Ribeiro de Freitas , Santana Júnior João Pedro Ferreira de , Oliveira Flávio José Vieira de
Published: December 2023

Objetivou-se neste trabalho avaliar o crescimento e desenvolvimento inicial do agrião (Barbarea versa). O experimento foi conduzido em casa-de-vegetação em delineamento inteiramente casualizado com 5 tratamentos: areia, areia/esterco (2:1), areia /humus (2:1), esterco/humus (2:1), e substrato comercial com cinco repetições. O tratamento T3 areia/húmus apresentou melhor desenvolvimento nos parâmetros agronômicos, altura da planta (ALT), comprimento da raiz (CR), número de folhas (NF), massa fresca (MF), massa seca (MS), de (Barbarea versa). Conclui-se que dentre os substratos utilizados T3 apresentou os melhores resultados em geral, com exceção do parâmetro CPR, no qual T5 se destacou estatisticamente. Esses resultados indicam que, tanto o T3 quanto o T5 são alternativas viáveis na produção de mudas de agrião da terra.
Diferentes temperaturas da água de irrigação na cultura da soja
Authors: Pereira Cassiano Spaziani , Sampaio Pamela do Carmo
Published: December 2023

A soja é uma planta do gênero Glycine, seu grão teve seu consumo expandido nas últimas três décadas. O objetivo deste trabalho foi determinar o crescimento vegetativo da soja sob influência de diferentes temperaturas de água de irrigação no solo. O experimento foi conduzido no telado do setor do Viveiro da Universidade Federal de Mato Grosso – Campus de Sinop, do dia 08 de abril de 2022 a 22 de julho de 2022. O delineamento experimental em blocos casualizados, com cinco repetições (em vaso) estudando-se temperaturas da água de irrigação a saber:  10Cº, 20Cº, 30Cº, 40Cº, 40Cº, 50Cº e 60Cº. Foram utilizadas 5 repetições.  Avaliou-se altura de plantas (AP), área foliar (AF), massa seca de raiz (MSR), massa seca parte aérea (MSPA). A água aplicada por irrigação na cultivar  ANsc 89 109 deve estar na faixa de temperatura entre 10 e 30ºC. A aplicação de água com temperatura de 40ºC acima prejudica o crescimento vegetativo da cultura da soja, o que acarretará redução na produtividade final de grãos
Unraveling the potential: assessment of the effect of Azospirillum brasilense inoculated via seeds on the growth and production of Mombaça grass
Authors: Vieira Carlos Luiz , Zilocchi Miguel Giulianna , Figueiredo Emerson de Oliveira , Silva Gabriel Vinícius Batista da , Rocha Rafael Rosa , Oliveira Altacis Junior de
Published: December 2023

Nitrogen fertilization in pastures is considered one of the primary limiting factors that significantly enhance forage biomass production. Traditional chemical fertilizers used in crop cultivation are derived from petrochemical and mining industries. These production chains have undergone continuous and consistent structural changes year after year, affecting the prices of these inputs for farmers, consequently escalating production costs and even rendering investment in livestock farming unfeasible. For this reason, research becomes crucial to evaluate alternative techniques that can complement or fulfill the nitrogen demand in forage crops. The bacterium Azospirillum brasilense has emerged as a viable alternative to reduce costs in pasture establishment and maintenance, serving as a nitrogen source when compared to traditional sources. The objective of this study was to assess the effect of Azospirillum brasilense inoculation on the growth and production of Panicum maximum cv. Mombaça. The experimental design employed was a randomized complete block design with four treatments and four replications. Each plot consisted of three plants, resulting in a total of 48 experimental units. The treatments comprised: T1 - natural soil (NS), T2 - Azospirillum brasilense (BAC.), T3 - nitrogen topdressing (N), T4 - Azospirillum brasilense and nitrogen topdressing (BAC+N). Evaluations were conducted at 60 and 90 days after sowing (DAS), assessing the following variables: plant height (PH), number of leaves (NL), number of tillers (NT), aboveground green biomass (AGGB), aboveground dry biomass (ADBB), root fresh biomass (RFB), and root dry biomass (RDB). Significant effects (P<0.05) were observed for inoculation and nitrogen topdressing on the assessed traits: plant height, number of leaves, number of tillers, aboveground green biomass, aboveground dry biomass, root fresh biomass, and root dry biomass. Notably, nitrogen topdressing either solely or in combination with seed inoculation of the forage yielded positive outcomes for all studied variables at both 60 and 90 DAS. A favorable impact on the development of Mombaça grass was evident across all parameters studied in samples receiving nitrogen topdressing and Azospirillum spp. inoculation.
Morphophysiological changes in Bauhinia cheilantha (Bong.) Steud. (Fabaceae) caused by water deficit
Authors: Freitas Rafael Silva , Santos Júnior José Laurindo dos , Silva Elizamar Círiaco da
Published: December 2023

Drought-induced alterations often result in plant acclimation responses, though the extent to which these traits adjust, and their true significance remain species-specific and subject to debate. In order to discern which traits exhibit plasticity and essentiality for the species' survival, we studied the morpho-physiological responses of Bauhinia cheilantha seedlings subjected to varying water regimes. We examined modifications in growth patterns, resource allocation and partitioning, morphological traits, organic solute synthesis, relative water content in leaves and roots, and the plasticity index for each trait under different water supply levels. Several traits linked to plant growth were reduced under stress, but those changes were not considered to be plastic. The concentration of organic solutes increased under stress and exhibited a reversible behavior by reducing their levels after re-irrigation. These alterations underscored the significance of such compounds for survival during water deficit periods and the high degree of adaptability. B. cheilantha exhibits morpho-physiological plasticity, as demonstrated by alternating high levels of plasticity in physiological and morphological features, which are associated with moderate drought stress. The study discusses how these changes affect the growth and survival of the species.
Análise da prevalência de consumo de alimentos ultraprocessados entre crianças de 6 a 24 meses atendidas em um município de Goiás
Authors: Perez Patrícia , Gonçalves Bárbara Rocha , Gonçalves Aguiar Anna Luísa , Ferreira Vasconcelos Beatriz , Peixoto Carvalho Gabriela , Queiroz Ferreira Letícia , Silva Tavares Ricardo , Marques Pacheco Lucivânia
Published: December 2023

Introdução: Os alimentos in natura foram substituídos pelos processados e por ultraprocessados e um fator que contribui para a adesão a essa alimentação nos primeiros anos de vida das crianças foi que as mulheres, que antes eram responsáveis pela alimentação em suas casas, foram inseridas no mercado de trabalho. Objetivo: Este estudo tem como objetivo analisar a prevalência do consumo de alimentos ultraprocessados entre crianças de 6 a 24 meses atendidas no CAIS de Itumbiara. Metodologia: A pesquisa realizará um estudo transversal exploratório de abordagem quantitativa. O estudo será realizado no CAIS - Centro de Atenção Integrada à Saúde por meio de aplicação de questionário. Resultado Encontrado: A respeito dos alimentos dispensados as crianças, todos os cuidadores relataram dar água a elas e mais da metade dessas crianças consomem suco (54,40%), iogurte (51,50%), biscoito (64,70%) e bolacha (69,10%). Aproximadamente um terço dessas crianças consomem também chá (35,60%), café (33,80%), bebida láctea (32,40%), salgadinhos (35,30%) e doces em geral (36,80%). Os alimentos menos consumidos foram refrigerantes (25,00%), macarrão instantâneo (20,60%), papinhas industrializadas (22,10%) e gelatina (27,90%). Conclusão: O consumo de alimentos ultraprocessados está presente precocemente na alimentação das crianças menores de 24 meses de idade.
O uso de ferramentas de bioinformática para análise de dados genéticos: uma revisão
Authors: Silva Ruana Carolina Cabral da , Alves Maria Cidinaria Silva
Published: December 2023

A bioinformática vem revolucionando o modo como os cientistas analisam e interpretam os dados genéticos. Dessa forma, esta revisão destaca o papel fundamental das ferramentas de bioinformática na compreensão dos dados genômicos. O artigo explora a diversidade de softwares e algoritmos disponíveis para processar, analisar e interpretar dados genéticos. Aborda-se a relevância dessas ferramentas na identificação de genes, variações genéticas, predição de estruturas proteicas e estudos de evolução e filogenia. Além disso, são apresentados os desafios enfrentados na bioinformática, incluindo a integração de dados de diferentes fontes, padronização e interpretação dos resultados. É disponibilizado no artigo informações sobre alinhamento de sequências, limpeza de dados de sequenciamento, que são dados importantes quando se trabalha com conjunto de dados genéticos. Destaca-se ainda que discussões como estas são importantes, pois as ferramentas de bioinformática estão constantemente evoluindo, o que requer atualização constante de conhecimento e habilidades por parte dos pesquisadores.
Research of stamping of unequal channels. Part 8. Deformed state and hardening of the workpiece under constrained extrusion. 1. Plastic zone under the formed thick wall
Authors: Vorontsov A.L.
Published: December 2023

The beginning of the solution of the problem of determining the deformed state of the workpiece under constrained extrusion of unequal channels under conditions of plane strain in the general case of misalignment of the punch and matrix is outlined. Formulas are obtained that allow, for any working stroke of the punch, to determine the current coordinates of the points and the ac cumulated deformations in the plastic deformation zone located under the extruded thick wall.

Keywords: die forging, extrusion, misalignment of the punch and matrix, plane strain, accumulated deformations, hardening.
mt13@bmstu.ru
Graph-analytical study of kinematic processes in gear chain hinges
Authors:   Volhonov M.S. Skripkin S.P.
Published: December 2023

The results of a graphoanalytical study of the processes of interaction of the sprocket with the links of the drive gear chain are presented. It is established that in gear chains with rolling joints, an increase in the contact step of the chain occurs in the process of engagement of the chain with the sprocket. The process of changing the contact step is carried out by turning the sprocket by two angular steps. The phenomenon of changing the contact step increases the unevenness of the chain movement and is undesirable. Recommendations are given for reducing dynamic loads in a drive with toothed chains.
Keywords: drive gear chain, sprocket, contact step, hinges, plates.
vms72@mail.ru, s.skri pkin.1936@mail.ru
Import substitution of grinding wheels
Authors: Varatkova J.V.
Published: December 2023

Domestic developments of highly structured grinding wheels with increased porosity are considered as a factor in import substitution of tools for foreign grinding machines. The effectiveness of their application is confirmed. Technological features and recommendations for the appointment of the optimal characteristics of the wheels are given.

Keywords: import substitution, high-structured grinding wheel, porosity, abrasive, characteristics of the grinding wheel.
volgashlif@mail.ru
Features of compaction of iron-cast-iron charge at different stages of pressing
Authors: Djafarova A.A.
Published: December 2023

The article presents the packing parameters of spherical particles and the characteristics of the granular medium of the iron-cast iron powder mixture. A mathematical analysis is carried out, giving preference to inertial methods of molding products from iron-iron charge. The complexity of obtaining a uniform dependence of the density of an elasticplastic medium on the pressing pressure is shown, taking into account the difference in the mechanisms of compaction of powders at different stages of pressing.

Keywords: pressing, powder, particle, coordination number, deformation, packing, granular medium, differential equations.
afetceferova8@gmail.com
Influence of wear-resistant coatings on tribological processes in the contact zone during materials cutting
Authors:   Aliev M.M. Fomenko A.V. Fominov E.V. Shuchev K.G. Mironenko A.E.
Published: December 2023

The influence of thin-layer wear-resistant tool coatings on thermophysical processes in the contact zone during metal cutting are studied. Longitudinal turning of workpieces made of 45, 12Х18Н9Т steels and ВТ3-1 titanium alloy by carbide cutters with TiC, TiN, ZrN, TiN + ZrN and Cu coatings deposited by cathode-ion bombardment are experimentally studied. The antifriction properties of coatings, cutting forces, wear resistance of cutters, temperature in the processing zone and temperature gradients in cutting inserts with different coatings and without them were evaluated. It has been established that these coatings do not have antifriction properties and do not reduce cutting forces, but reduce the surface and bulk temperature of the tool material.

Keywords: cutting, cutting tool, friction coefficient, cutting force, wear, temperature, coating, wear resistance.
m_aliev62@mail.ru
Prospects for the use of plastic satellites with a steel band in planetary cycloid gears
Authors:   Zakharov M.N. Ermolaev M.M. Kuralina N.N.
Published: December 2023

A method is proposed to reduce the effect of manufacturing errors on the load capacity of a planetary cycloidal gear by replacing a satellite made of solid material (steel or plastic) with a satellite with a plastic core and a steel band on the working profile. A formula is derived for estimating the load factor, which takes into account the influence of manufacturing accuracy on the load capacity of the gear. A method for estimating the contact stiffness of a satellite with a band, as well as the torsional stiffness of the gear, is proposed. The calculation shows that the allowable torque on the gear cage with a banded satellite is more than 3 times greater than the torque on the cage in a gear with a solid satellite, however, the torsional rigidity of the drive can significantly decrease in this case.
Keywords: cycloidal gearbox, cycloidal satellite, manufacturing error, gear wheel band. mmermolaev@gmail.com
Determination of residual stresses in thin coatings by their deflection after delamination
Authors: Voronin N.A.
Published: December 2023

A technique is developed for determining residual stresses in thin coatings of top composites by their curvature, which occurs during interfacial delamination of the coating from the substrate as a result of microindentation.

Keywords:
top composite, hard coating, residual stresses, instrumental indentation, penetration diagram, interfacial failure.
voroninn@inbox.ru
Dynamic modeling and analysis of a new coaxial magnetic multiplier for size-limited hydraulic channels
Authors:   Bashmur K.A. Abramov Yu.V.
Published: December 2023

A magnetic transmission designed to improve the effectiveness and reliability of space-limited hydraulic channels is considered. The axial moments of rotation of high-speed and low-speed rotors, as well as the densities of radial magnetic fields in the air gaps of the high-speed rotor-modulator and modulator-stator pairs obtained by computer simulation are given. The stability of the magnetic multiplier is confirmed.

Keywords: magnetic transmission, magnetic multiplier, computer simulation, system stability, size-limited hydraulic channels.
bashmur@bk.ru, abr.yury@mail.ru
Dependences of the tribological properties of high-speed steels on their thermoelectric parameters
Authors:   Fominov E.V. Shuchev K.G. Aliev M.M. Marchenko A.A. Lavrenova T.V.
Published: December 2023

The influence of thermoelectric parameters of high-speed steels (HSS) on their tribological properties during friction with structural materials without lubricant is investigated. It is established that the friction of HSS with low thermo-EMF is accompanied by an intensive growth of secondary structures in the gap of the friction pair, and the formed intermediate layer has a high shielding effect, which minimizes the change in the microrelief of the contacting surfaces relative to the initial state.

Keywords: high speed steel, absolute thermo-EMF, friction, lubricant, surface roughness parameter.
fominoff83@mail.ru
Research of the influence of tool microgeometry on technological heredity at combined hole burnishing
Authors:   Schedrin A.V. Minyazeva L.H. Bekaev А.А. Chikhacheva N.Yu. Burlakova T.A.
Published: December 2023

With the use of algorithmic procedures of artificial technological intelligence, the technological inheritance of accuracy parameters in the combined burnishing of holes in workpieces made of 12ХН3А steel with a tool with a regular microrelief is investigated.

Keywords: regular microrelief, technological inheritance, combined burnishing of holes.
miluiza@yandex.ru, nadezhdachi@yandex.ru, ld-gim@yandex.ru
Technical equipment of workshop production and logistics systems: selection of equipment models
Authors:   Lazarenko A.G. Lazarenko G.P.
Published: December 2023

The prerequisites for automating the selection of equipment in the design of workshop production and logistics systems are analyzed, which is based on the theory of making multi-criteria decisions. A variant of a formalized approach for solving this problem is considered.

Keywords: production and logistics systems, design, equipment selection, formalized approach, comparative analysis.
a.g.lazarenko@yandex.ru
СОВРЕМЕННЫЕ ПРОБЛЕМНЫЕ ВОПРОСЫ УЧАСТИЯ АДВОКАТА В ПРОЦЕССЕ ДОКАЗЫВАНИЯ ПО УГОЛОВНОМУ ДЕЛУ
Authors: Эльмурзаев С.М , Катаев У.Ш.
Published: December 2023

После принятия УПК РФ в 2001 году стартовал процесс совершенствования системы национального уголовного судопроизводства с акцентом на развитие принципа состязательности и равенства участников в ходе судебных разбирательств. Следующим этапом модернизации системы уголовного судопроизводства стало утверждение закона, регламентирующего адвокатскую деятельность. Эти нововведения наделили адвокатов возможностью участвовать в процессе сбора доказательств, несмотря на то, что конкретные методики этого процесса не были в полной мере очерчены. Таким образом, адвокаты получили дополнительное право активного участия в организации защиты. Для реализации этого права закон предложил ряд инструментов, включая доступ к ресурсам, взаимодействие с правоохранительными органами и привлечение экспертов. На данный момент указанные инструменты широко используются в адвокатской деятельности в процессе доказывания. Тем не менее, у некоторых судей и следователей сохраняется определенный скепсис о повышении прав адвокатов в процессе доказывания. Учитывая ключевую роль этого процесса в уголовной сфере, его критическое исследование является особенно актуальным. Объектом исследования выступает роль адвоката в процессе доказывания по уголовному делу. Цель – комплексная характеристика прав участия адвоката в процессе доказывания по уголовному делу в действующем законодательстве РФ, а также выявление проблем в данной области. Методы исследования – диалектический подход к анализу реальности, документальный метод, общенаучные методы, сравнительно-правовой, логико-правовой методы. Научная новизна – формирование проблемной базы для развития уголовно-процессуальной практики.
FEATURES OF PRICING OF AMBER PRODUCTS IN MODERN CONDITIONS
Authors: Baranov P. , Korotaiev V. , Slyvna O.
Published: December 2023

The purpose of the scientific article is to identify the pricing patterns of raw amber and amber products in modern conditions based on market analysis and interpretation of information in terms of decorative and consumer properties, technological processes of processing. Methodology. The methodological basis of the research is based on general and special methods of scientific cognition. The study uses general scientific and special research methods: analytical, dialectical, comparative legal, systemic and structural, comparative and evaluative, gemological and economic. The main part of the work is based on the practical results of previous research and expert assessments. The scientific novelty lies in the identification of natural relationships between the weight of products and their cost, between the weight of raw materials intended for the manufacture of a given product and the cost of raw materials. This is used to distinguish the market value, the commercial or marketing value and the forecast value, which reflects real prices, and is used to draw up business plans and expert reports. Results. It is proved that the modern amber market is characterised by the widespread use of Internet resources for the sale of goods, promotion of online sites and shops. It is argued that prices in price lists and on websites of mining, processing and trading companies require systematic analysis in order to understand their formation for amber and amber products. The article reveals natural relationships in pricing of raw amber and amber products in modern conditions based on market analysis (the results are visualized in the form of graphs and illustrated with examples) and interpretation of information, taking into account decorative and consumer properties, technological processes of processing. The author proposes a procedure for determining the market, commercial and forecast value, which consists of the following steps: studying the consumer properties (colour, weight, size, inclusions and cracks, transparency, processing quality, cost); filling the database with information based on the results of the research; using an SQL program to process the results and calculate the cost of raw materials for a sample, the cost of raw materials per gram, and determining the weight of raw materials for the manufacture of a given product. The visualized results of this scientific research are of particular importance in connection with the requirements of the legislation of Ukraine on forensic examination, which defines the principles on which forensic activities are carried out, including the objectivity and completeness of the study
ОСОБЛИВОСТІ БУДОВИ, РОЗРАХУНКУ ТА ЕКСПЛУАТАЦІЇ ГІДРОКУЛЕУЛОВЛЮВАЧІВ
Authors: Ганзюк А. Л. , Кравчук О. В. , Гордєєв А. І.
Published: December 2023

Анотація. Науковий прогрес і технологічний розвиток допомагають постійно вдосконалювати техніко-криміналістичні пристрої та методи, що дозволяє криміналістам ефективніше проводити розслідування кримінальних правопорушень і забезпечувати судову практику достовірними доказами. У цьому контексті набуває актуальності порушена проблематика в аспекті обґрунтування конструкції гідрокулеуловлювача та його вузлів за критерієм «ціна – якість», розвитку аналітичних основ розрахунку основних конструктивних параметрів гідрокулеуловлювача для експертних досліджень під час проведення контрольних відстрілів зброї. Методологія. Достовірність отриманих результатів і висновків забезпечено використанням загальнонаукових (емпіричних та теоретичних) і спеціальних методів дослідження. Так, зокрема, загальнонауковими методами дослідження (аналіз, синтез, узагальнення) схарактеризовано наукові та інформаційні джерела за тематикою дослідження, з’ясовано рівень достатності в них профільної інформаціїдля реалізації поставленої мети. За допомогою аналітичних і емпіричних методів дослідження визначено конструктивні параметри запропонованих засобів. Системний підхід до проведення дослідження забезпечив його комплексний характер і дозволив об’єднати окремі результати дослідження (за методологією виконання досліджень зброї) в єдине ціле. Наукова новизна цієї статті полягає в подальшому розширенні перспективних напрямів розвитку інноваційного спеціального технічного устаткування (гідрокулеуловлювачів) для проведення криміналістичних досліджень зброї під час аналізування досліджуваних об’єктів. Запропоновано аналітичну залежність розрахунку довжини камери гідрокулеуловлювача та обґрунтовано концепцію вузла ефективного вилучення кулі. Здобуті результати. З’ясовано, що в Україні перспективним рішенням, зважаючи на проблему «ціна – якість», є використання горизонтальних або вертикальних гідрокулеуловлювачів. Запропоновано аналітичну залежність розрахунку основних конструктивних параметрів спеціальних конструкцій технічного устаткування для проведення досліджень зброї в разі підготовки та призначення судових експертиз у межах розслідування кримінальних правопорушень. Розкрито особливості практичного використання запропонованого інноваційного спеціального технічного устаткування для дослідження зброї.
«СПРАВА БЕЙЛІСА» (1911–1913): ОПЕРАТИВНО-РОЗШУКОВИЙ І КРИМІНАЛІСТИЧНИЙ АНАЛІЗ (до 110-ї річниці судового процесу)
Authors: Чисніков В. М. , Юсупов В. В.
Published: December 2023

Ґрунтуючись на аналізі архівних матеріалів кримінальної справи щодо вбивства Андрія Ющинського, оприлюднених спогадів учасників цього процесу про проведення розшукових заходів, слідчих дій і судового розгляду у «справі Бейліса», у контексті наукового осмислення оперативно-розшукових та криміналістичних аспектів кримінального провадження у зазначеній справі, що становить мету цієї статті, розглянуто вплив зовнішніх і внутрішніх чинників на процес розслідування та судового розгляду справи, висунення версій за фактом виявлення трупа Андрія Ющинського та проведених слідством заходів для їх перевірки, заналізовано негласні заходи, слідчі (розшукові) дії, проведені експертизи у «справі Бейліса», головні положення судового процесу, у якому взяли участь видатні експерти того часу. Методологія. Для досягнення поставленої мети застосовано, зокрема, історико-правовий, історико-порівняльний і біографічний, порівняльно-правовий, формально-юридичний методи. Наукова новизна. На прикладі відомої кримінальної справи (1911–1913 рр.) за фактом убивства тринадцятирічного хлопчика Андрія Ющинського здійснено оперативно-розшуковий і криміналістичний аналіз процесу розслідування та судового розгляду «справи Бейліса», визнаної справою про ритуальне вбивство. Здобуті результати. Засвідчено вплив і втручання посадових осіб відомств юстиції, внутрішніх справ та поліції на процес попереднього розслідування вбивства з метою визнання його ритуальним злочином юдеїв. Схарактеризовано версії слідства, висунуті на початковому етапі розслідування: вбивство А. Ющинського вчинено його батьками через особисті неприязні стосунки; вчинення юдеями ритуального вбивства А. Ющинського; убивство А. Ющинського вчинили спільники з банди Віри Чеберяк. Розкрито головні оперативно-розшукові заходи та слідчі дії, проведені для перевірки висунутих версій. При підтвердженні негласними заходами та слідчими діями третьої версії, на підставі внутрішньої протидії розслідуванню, до суду було скеровано обвинувачення у вчиненні ритуального вбивства Ющинського євреєм М. Бейлісом. З’ясовано місце і значення висновків судово-медичної, психіатрично-психологічної та ритуальної експертиз у процесі судового доказування. Унаочнено роль відомих криміналістів та судових експертів початку ХХ ст. в дослідженні окремих обставин спричинення Андрію Ющинському насильницької смерті, оголошенні висновків експертів та їх перехресного допиту у суді. З огляду на досліджені речові докази та показання учасників процесу продемонстровано справедливість судового рішення про визнання Менделя Бейліса невинуватим у вчиненні вбивства, водночас визнаного ритуальним.
Resection and Re-resection for a Clear Cell Renal Carcinoma with Sarcomatoid Features in a Patient with Birt-Hogg-Dubé Syndrome
Authors: Callens Louise
Published: December 2023

Background: Birt-Hogg-Dubé syndrome (BHDS) is a rare monogenic autosomal dominant disorder which is, among other disease manifestations, associated with an increased life-time risk of developing renal cell carcinoma (RCC). Sarcomatoid RCC (sRCC) is a subtype of RCC associated with poor prognosis, high recurrence rates, and a significant resistance to a variety of systemic treatments. Case Report: Here, it is reported that the first case of a sRCC with local recurrence in a 62-year-old female patient with BHDS. This patient was successfully treated with a partial robotic nephrectomy and a re-resection of the tumor recurrence resulting in good short-term oncological outcomes. Conclusions: Robotic partial nephrectomy for sRCC, and robotic re-resection for locally recurrent sRCC in BHDS patients is a feasible treatment strategy associated with good short-term oncological outcomes. Due to the high risk of local and distant recurrences in sRCC cases, a lifelong follow-up with regular imaging is recommended.
Maharani's Misery
Authors: Shepherd Verene A.
Published: December 2023

Maharani’s Misery sheds new light on the ordeal of indentured Indians, especially women, as they crossed the oceans to labour on sugar plantations in the Caribbean (and elsewhere) in the nineteenth century. Narrating the tragedy of a young woman who died on one such passage, apparently after being raped by crewmen, the book analyses “sexploitation” as a routine aspect of the voyages of the “coolie ships”. The testimonies of those who gave evidence to the resulting enquiry in 1885 are included verbatim, an attempt to recover the voices of some of the indentureds, men and women, voices we rarely hear in the official documentation. This book is a valuable addition to the growing literature on nineteenth-century indentured Indian immigration/emigration and a gripping account of one woman’s tragedy. - Professor Bridget Brereton, University of the West Indies, St Augustine, Trinidad Maharani is a most significant contribution to the new generation of scholarship on the history of Indian indentured migration, deeply researched and sensitive to the new approaches of intellectual enquiry. The author’s ability to read the contemporary texts against the grain of official pronouncements and popular prejudice against women in particular and indentured labourers generally, is truly impressive. I have no doubt that this book will find a place on the shelves of every serious scholar of the subject. - Professor Brij Lal, Australian National University, Canberra Maharani’s Misery is a major contribution to the “peopling” of Indo-Caribbean history in the late nineteenth century…. It enables us to go beyond the inanimate history which speaks primarily of the power of the indentureship system, the process of controlling the “bound coolies”. Here, the “subaltern” has a voice even in the midst of the tragedy one gets a feel for the women as actors, however minor. The work belongs, also, to the history of resistance in the region. -Dr Clem Seecharan, University of North London