bluuebunny/crossref_metadata_2025 huggingface dataset:
PENERAPAN DRAGONFLY OPTIMIZATION ALGORITHM (DOA) PADA PERMASALAHAN MULTIPLE CONSTRAINTS BOUNDED KNAPSACK
Authors: Nilasari Laylatul Febriana , Santoso Kiswara Agung , Riski Abduh
Published: August 2020

Optimization is very useful in almost all fields in running a business effectively and efficiently to achieve the desired results. This study solves the problem of multiple constraints bounded knapsack by implementing DOA. The problem of multiple constraints bounded knapsack has more than ones constraint with objects that are entered into the storage media, the dimensions can be partially or completely included, but the number of objects is limited. The purpose of this study is to determine the results of using DOA to solve multiple constraits bounded knapsack and the effectiveness of DOA compared to the results of the Simplex method. The data used in this study are primary data. There are ten parameters to be tested, namely population parameters, maximum iteration, s, a, c, f, e and range. The trial results of the ten parameters show that the best value of the parameters is neither too large nor too small. If the best value is too large then the position of the dragonfly will be randomized so that it is not clear the position of the dragonfly and if it is too small the best value then the change is not visible. In addition, based on the results of the final experiment it can be seen that DOA is less effective in solving multiple constraints bounded knapsack problems, because of many experiments there is no solution similar to Simplex. DOA approach to optimal, seen from a small deviation.

Keywords: DOA, Knapsack, Multiple constraints bounded knapsack problem.
ANALISIS STRUCTURAL EQUATION MODELING (SEM) DENGAN MULTIPLE GROUP MENGGUNAKAN R
Authors: Holipah Holipah , Tirta I Made , Anggraeni Dian
Published: August 2020

Structural Equation Model (SEM) is a statistical technique with simultaneous processing involves measurement errors, indicator variables, and latent variables. SEM is used to test hypotheses that state the relationships between latent variables when latent variables have been assessed through each of the indicator variables. Multiple Group SEM is a basic model analysis that uses more than one sample. This analysis aims to determine whether the components or models of measurement and structural models are invariant for the two sample groups. In this study, the data generated by some requirements. First, the data generated with sample size n = 250. The first generated data is homogeneous data where the measurement model is the same as the structural model in group 1 and group 2, while the second data is non-homogeneous data where the measurement model and the structural model in group 1 and group 2 is not the same. The data was analyzed using the help of the lavaan package available in R to obtain SEM estimation results and Goodness of Fit Model from some data that was formed. From the results of the merger of the two groups, it shows that the invariant of the two models with the largest df (63) which is Fit Mean model states the simplest model. However, the smallest df (48) with Fit.configural model states the most complex model.

Keywords: SEM, Multiple Group, R Program
PENGAMANAN POLYALPHABETIC DENGAN AFFINE CIPHER BERDASARKAN BARISAN FIBONACCI
Authors: Astuti Lestari Fidi , Santoso Kiswara Agung , Kamsyakawuni Ahmad
Published: August 2020

Affine cipher is a classic cryptographic algorithm substitution technique. Substitution technique is the encryption process for every character in the plaintext will be subtituted by another character. Affine cipher uses two types of keys. Each character of plaintext to be encrypted substituted by the same key. This research discusses about modify one of the key affine cipher, to produce a different key that will be substituted with each plaintext character. Key modifications are made by the Fibonacci sequence rules. This study also compares affine cipher and key modification affine cipher by finding corelation coeffiecient values. The results obtained from the comparison of the two algorithms, encryption that uses affine cipher key modification is better than affine cipher.

Keywords: Cryptography, Affine Cipher, Fibonacci, Correlation Value
PEMODELAN FAILURE TIME PADA MAHASISWA BERHENTI STUDI DI UNIVERSITAS JEMBER
Authors: Hanifia Fidiatma Foristy , Fatekurohman M. , Anggraeni Dian
Published: August 2020

Problems in higher education concerning students are always interesting objects studied from any side. One of the problems faced by universities and students is stopping study. Stopping the study of students became a problem in universities, including the University of Jember. One of the statistical methods used is Survival Analysis. In its development, survival analysis was carried out by combining the concepts of Geometric regression. Geometric is one of the non linear regression for discrete data. Geometric regression modeling cannot be done with ordinary linear modeling, but must be done using the Generalized Linear Model (GLMs) method. In this study the variables used were gender, GPA, faculty, age of entry and entry point. The results of the study students stopped studying in the first semester 140 students. Average GPA of 1.54. 62.85% male sex. Student faculty of education and teacher stopped most studies. The student entry pathway stopped the most SBMPTBR studies and 54.40% were 18 years old. Significant influential factors for stopping the study were GPA, gender and entry point. From the Geometric opportunity, it was found that female students were slower when they stopped studying than men. The faculty stops studying at the latest is the Faculty of Medicine. Keywords: Drop Out, Failure Time, Regrition Geometric Method
Quantitative clay mineralogy as a tool for lithostratigraphy of Neogene Formations in Belgium: a reconnaissance study
Authors: ADRIAENS Rieko , VANDENBERGHE Noël
Published: August 2020

Although the main stratigraphic frame of the Neogene in North Belgium is well established still several issues remain. This is in particular the case at the boundaries of lithostratigraphic units and where lateral facies have developed. Not only are more biostratigraphic data needed but also the commonly used geophysical well logging needs a better information on the precise influence of the variable mineralogy in the sediments. In particular glauconite, muscovite and clay mineralogy need a detailed analysis. Such an analysis is carried out on the Antwerp Member of the Berchem Formation, the Diest Formation, the Kasterlee Formation and the Mol Formation with particular emphasis on the boundary intervals between these units. Clay minerals, glauconite, feldspars and muscovite are analyzed. Interstratified glauconite/smectite appears to be common in the low abundant dispersed clay fraction of sand rich in glauconite pellets. Marine units generally consist of detrital smectite-rich assemblages while kaolinite becomes more abundant in units under more continental influence. The presence of Fe-rich vermiculite in a clayey top facies of the Diest Formation indicates the influx of soil material containing weathered glauconite. It is common to find that the basal sediments of a new unit contain the mineralogical heritage of the underlying unit. The clay mineral content has helped to differentiate between units, to locate the boundaries between units and to understand the reworking that occurred at the base of new stratigraphic units. The mineralogical information can also be used to interpret the natural radioactivity and resistivity signals in the borehole logs.
Vloga čustvenčkov in čustvenih simbolov pri socialnem inženiringu
Authors: Fujs Damjan , L. R. Vrhovec Simon , Mihelič Anže
Published: August 2020

Namen tega prispevka je umestiti rabo čustvenčkov in čustvenih simbolov v komunikaciji, npr. preko socialnih omrežij in SMS-ov, na področje socialnega inženiringa. S sistematičnim pregledom literature v akademskih bazah podatkov Web of Science in Scopus ter oportunističnim iskanjem je bilo identificiranih 40 znanstvenih člankov, ki obravnavajo uporabo čustvenčkov in čustvenih simbolov pri socialnem inženiringu. Raba čustvenčkov in čustvenih simbolov v komunikaciji je oblika neposredne komunikacije, saj pošiljatelj z njimi neposredno vpliva na prejemnika. Čustvenčki in čustveni simboli so univerzalno orodje, ki ga na podoben način razumejo vsi uporabniki komunikacijskih tehnologij ne glede na demografske značilnosti. Večina identificiranih študij uporablja kvantitativni pristop ter obsega različna področja, kot so marketing, psihologija, sociologija itd. Pričujoči prispevek predstavlja enega prvih sistematičnih pregledov literature, ki obravnavajo čustvenčke in čustvene simbole v kontekstu socialnega inženiringa. Rezultati prispevka nudijo temelje za nadaljnje, predvsem kvalitativne raziskave.
Time, Equilibrium, and General Relativity
Authors: Hollestelle Harmen Henricus
Published: August 2020

Considered is “time as an interval” including time from the past and from the future, in contrast to time as a moment. Equilibrium as the basis for a description of changing properties in physics is understood to depend on the “mean velocity theorem”, while a “time” of equilibrium resembles a center of weight. This turns out to be a good method to derive properties for any function of time t including space coordinates q(t) and expressions for the time dependent Hamiltonian. Introduced are derivatives depending on time intervals instead of time moments and with these a new relation between the Lagrangian L and the Hamiltonian H. As an application introduced is a step by step method to integrate stationary state “local” time interval measurements to beyond “locality” in General Relativity. Because of limits on the measures of the resulting time intervals and their asymmetry, this allows for a probabilistic interpretation of quantities that have these intervals as time domain in QM. Their asymmetry also questions the time reversal symmetry of GR. Another application of time intervals is the discussion of the measurement of starlight radiation energy and QM wave packet collapse as an example of a time dependent Hamiltonian. Finally a relation between starlight frequency, metric and space- and time intervals is found. Discussed is how finite and asymmetric time intervals correspond to time dependent H and symmetric infinite time intervals to a time independent H. From there, in cosmological perspective, finite time intervals can help to describe how entropy change could relate to dark energy.
An Extended Re-selling Protocol For Existing Anti-Counterfeiting Schemes
Authors: Khalil Ghaith , Doss Robin , Chowdhury Morshed
Published: August 2020

Product counterfeiting is an on-going problem in supply chains and retail environments, Recently an anti-counterfeiting protocol to address this issue via cost-effective use of auto-identification technologies such as radio-frequency identification (RFID) was proposed by researchers.Yet the use case of re-selling the same product was not been fully addressed which might cause serious problem for the exciting and proposed schemes and transactions. This paper proposes an extended RFID-based anti-counterfeiting to address the use case of the original buyer reselling the same item to a second buyer. The extended scheme will be followed by a formal security analysis to show that the proposed protocol satisfies the requirements of security correctness and is resistant to compromise through security attacks.
Classical Mechanics as a Fundamental Law of Quantum Mechanics
Authors: Roth Yehuda
Published: August 2020

n our previous paper, we showed that the so-called quantum entanglement also exists in classical mechanics. The inability to measure this classical entanglement was rationalized with the definition of a classical observer which collapses all entanglement into distinguishable states. It was shown that evidence for this primary coherence is Newton’s third law. However, in reformulating a "classical entanglement theory" we assumed the existence of Newton’s second law as an operator form where a force operator was introduced through a Hilbert space of force states. In this paper, we derive all related physical quantities and laws from basic quantum principles. We not only define a force operator but also derive the classical mechanic's laws and prove the necessity of entanglement to obtain Newton’s third law.
Unsupervised Feature Selection Using Recursive k-Means Silhouette Elimination (RkSE): A Two-Scenario Case Study for Fault Classification of High-Dimensional Sensor Data
Authors: Mallak Ahlam , Fathi Madjid
Published: August 2020

Feature selection is a crucial step to overcome the curse of dimensionality problem in data mining. This work proposes Recursive k-means Silhouette Elimination (RkSE) as a new unsupervised feature selection algorithm to reduce dimensionality in univariate and multivariate time-series datasets. Where k-means clustering is applied recursively to select the cluster representative features, following a unique application of silhouette measure for each cluster and a user-defined threshold as the feature selection or elimination criteria. The proposed method is evaluated on a hydraulic test rig, multi sensor readings in two different fashions: (1) Reduce the dimensionality in a multivariate classification problem using various classifiers of different functionalities. (2) Classification of univariate data in a sliding window scenario, where RkSE is used as a window compression method, to reduce the window dimensionality by selecting the best time points in a sliding window. Moreover, the results are validated using 10-fold cross validation technique. As well as, compared to the results when the classification is pulled directly with no feature selection applied. Additionally, a new taxonomy for k-means based feature selection methods is proposed. The experimental results and observations in the two comprehensive experiments demonstrated in this work reveal the capabilities and accuracy of the proposed method.
A Study on the Determinants of some Hessenberg Toeplitz Bohemians
Authors: Feng Jishe , Fan Hongtao
Published: August 2020

In this paper, we deduce explicit formulas to evaluate the determinants of nonsymmetrical structure Toeplitz Bohemians by two determinants of specific Hessenberg Toeplitz matrices, which are linear combinations in terms of determinants of specific Hessenberg Toeplitz matrices. We get some new results very di¤erent from [Massimiliano Fasi, Gian Maria Negri Porzio, Determinants of normalized upper Hessenberg matrices, Electronic Journal of Linear Algebra, Volume 36, pp. 352-366, June 2020].
Experimental therapies of Mycobacterium abscessus infections
Authors: Meir Michal , Barkan Daniel
Published: August 2020

Mycobacterium abscessus is a non-tuberculous mycobacteria notoriously known for causing severe, chronic infections. Treatment of these infections is challenging due to either intrinsic or acquired resistance of M. abscessus to multiple antibiotics. Despite prolonged poly-antimicrobial therapy, treatment of M. abscessus infections often fails, leading to progressive morbidity and eventual mortality. Great research efforts are invested in finding new therapeutic options for M. abscessus. Clofazimine and rifabutin are known anti-mycobacterial antibiotics, repurposed for use against M. abscessus. Novel antimicrobials active against M. abscessus include delamanid, pretomanid and PIPD1 and the recently approved beta-lactamase inhibitors avibactam, relebactam and vaborbactam. Previously unused antimicrobial combinations e.g. vancomycin-clarithromycin and dual beta-lactam therapy have been shown to have synergistic effect against M. abscessus in experimental models, suggesting their possible use in multiple-drug regimens. Finally, engineered phage therapy has been reported to be clinically successful in a severe case of disseminated M. abscessus infection. While many of these experimental therapeutics have shown activity against M. abscessus in vitro, as well as intracellular and/or animal models, most have little if any evidence of effect in humans infections. Clinical studies of M. abscesssus treatments are needed in order to reliably determine the value of their incorporation in therapeutic regimens.
The Experimental Proteome of Leishmania infantum promastigote and Its Usefulness for Improving Gene Annotations
Authors: Sanchiz África , Morato Esperanza , Rastrojo Alberto , Camacho Esther , Gonzalez-De la Fuente Sandra , Marina Anabel , Aguado Begoña , Requena Jose M.
Published: August 2020

Leishmania infantum is causative of visceral leishmaniasis (kala-azar), the most severe form of leishmaniasis, lethal if untreated. Few years ago, re-sequencing and de novo assembling of the L. infantum (strain JPCM5) genome was accomplished, and now we aimed to describe and characterize the experimental proteome of this species. In this work, we have performed a proteomic analysis from axenic cultured promastigotes and carried out a detailed comparison with other Leishmania experimental proteomes published to date. We identified 2,352 proteins based on the search of mass spectrometry data against a database built from the six-frame translated genome sequence of L. infantum. We have detected many proteins belonging to organelles such as glycosomes, mitochondria or flagellum, as well as many metabolic enzymes, and a large number of putative RNA binding proteins and molecular chaperones. Moreover, we listed the proteins presenting post-translational modifications, such as phosphorylations, acetylations and methylations, among others. On the other hand, the identification of peptides mapping to genomic regions previously annotated as non-coding has allowed to correct annotations, leading to N-terminal extension of protein sequences, and the uncovering of eight novel protein-coding genes. The alliance of proteomics, genomics and transcriptomics has resulted in a powerful combination for improving the L. infantum reference genome annotation.
Insight Into Unprecedented Diversity of Cyanopeptides in Eutrophic Ponds Using a MS/MS Networking Approach
Authors: Kust Andreja , Řeháková Klára , Vrba Jaroslav , Maicher Vincent , Mareš Jan , Hrouzek Pavel , Chiriac Cecilia , Benedová Zdeňka , Tesařová Blanka , Saurav Kumar
Published: August 2020

Man-made shallow fishponds in the Czech Republic have been facing a high eutrophication since 1950s. Anthropogenic eutrophication and feeding of fish have strongly affected the physico-chemical properties of water and its aquatic community composition leading to harmful algal bloom formation. In our current study, we have characterised the phytoplankton community across three hypertrophic ponds to assess the phytoplankton dynamics during the vegetation season. We microscopically identified and quantified 29 cyanobacterial taxa comprised of non-toxigenic and toxigenic species. Further, a detailed cyanopeptides (CNPs) profiling was performed using molecular networking analysis of liquid chromatography tandem mass spectrometry (LC–MS/MS) data coupled with dereplication strategy. This MS networking approach coupled with dereplication on online global natural product social networking (GNPS) web platform led us to putatively identify forty CNPs: fourteen anabaenopeptins, ten microcystins, five cyanopeptolins, six microginins, two cyanobactins, a dipeptide radiosumin, a cyclooctapeptide planktocyclin and epidolastatin12. We have applied the binary logistic regression to estimate the CNPs producer by correlating the GNPS data with the species abundance. Usage of The combination of molecular networking and dereplication on online global natural product social networking (GNPS) web platform has proved as a valuable approach for rapid and simultaneous detection of high number of peptides, and rapidly assessing the risk for harmful bloom.
How Parks Provide Thermal Comfort Perception in the Metropolitan Cores; A Case Study in Madrid Mediterranean Climatic Zone
Authors: Aram Farshid , Solgi Ebrahim , Baghaee Sepideh , Higueras García Ester , Mosavi Amir , Band S.
Published: August 2020

The combined effects of global warming and increasing urban heat islands (UHIs) on air temperature and heat stress in cities are notable physical and mental health implications for citizens. With research having shown the effective role of urban green spaces in decreasing urban heat, this study investigated the cooling effect of a large urban park on thermal comfort outside the park area, from psychological and physiological perspectives. The studied park is located in the center of Madrid and adjacent to UHI. The study was performed by conducting field measurements and a survey with questionnaires. The measurements made on six summer days (with two-week intervals) showed that the park’s cooling effect could decrease the air temperature by 2.4-2.8°C right up to the edge of the heat island (600m), and decrease the physiological equivalent temperature (PET) by about 3.9°C. By decreasing air temperature and PET, this park was also shown to increase the perceived thermal comfort (PTC) of the citizens from the psychological perspective in the defined area of effect. This perceived thermal comfort was found to have a significant inverse relationship with PET (P-value <0.05). The examination of cognitive maps drawn by citizens showed that out of the 145 respondents, 68.3% marked the park as the area that they perceive as having the greatest thermal comfort, and prefer as the place to spend time enjoying thermal comfort, irrespective of its distance from their location.
The Impacts of COVID-19 on Indonesian Poverty and Unemployment
Authors: Bahri Muhamad
Published: August 2020

This study estimates the negative impacts of the COVID-19 on poverty and unemployment in Indonesia. In doing so, this study develops and uses the SD model that reproduced similar patterns in terms of GDP, poverty, and unemployment. Estimated unemployment and estimated poverty under the COVID-19 are calculated for three different economic scenarios: the optimistic, the mid, and the pessimistic scenarios. This study concludes that Indonesia will experience rising unemployment and poverty in ranges (9-10) and (25-26) million people respectively by the end of this year – depending on projected economy growths. This study suggests that existing financial aids are sufficient to support rising unemployment and rising poverty level. However, if the Indonesia government cannot carefully slow the COVID-19 flow, higher financial supports are required to curb the negative impacts of the COVID-19.
Volatile Compounds Emitted from the Cat Urine Contaminated Carpet Before and After Treatment with Marketed Cleaning Products: A Simultaneous Chemical and Sensory Analysis
Authors: Banik Chumki , Koziel Jacek , Flickinger Elizabeth
Published: August 2020

Urination on carpet and subflooring can develop into persistent and challenging to mitigate odor. Very little or no information is published on how these VOCs change over time when urine is deposited on the carpet covering a plywood-type subflooring. This research has investigated the VOCs emitted from carpet+subflooring (control), carpet+subflooring sprayed with water (control with moisture), and cat urine-contaminated carpet+subflooring (treatment) over time (day 0 and 15). In addition, the effect of popular cleaning products on VOCs emitted and evaluated their efficacy in eliminating those indoor odors over time (day 0 and 15). Carpet-subflooring with all treatments were also contaminated with Micrococcus luteus, nonmotile obligate aerobe commonly found in household dust, to observe the impact of the aerobe on carpet-subflooring VOCs emission. VOCs emitted from carpet+subflooring receiving different treatments were collected from headspace using solid-phase microextraction (SPME). The VOCs were analyzed using a multidimensional gas chromatography-mass spectrometer attached to an olfactometry (GC-MS-O). Many common VOCs were released from the carpet on day one and day fifteen, specifically from urine contamination. Cleaning products were effective in masking several potent odors of cat urine contaminated carpet VOCs on day one but unable to remove the odor appeared on day 15 in most cases.
Çanakkale Savaşlarının Amerikan Basınındaki Yansımaları
Authors: GÜNDÜZ Mehmet
Published: August 2020

Gazeteler insanlara bilgi ulaştıran önemli kaynaklardandır. Bu kaynaklar tarihsel kanıt olma özelliğini ancak tarihçilerin onun karşısındaki tutumlarıyla edinirler. Tarihsel bir kaynak olarak gazeteler yayınladıkları dönemin anlaşılmasına yardımcı olurlar. Ayrıca bu kaynaklar okuyuculara bilginin nasıl sunulduğunun görülmesi ve dönemin algılarını göstermesi bakımından önemlidir. Hiç şüphesiz, yirminci yüzyılın ilk en önemli olayı Birinci Dünya Savaşı’dır. Bu savaşın da en önemli cephesi Çanakkale Cephesi’dir. Çanakkale’nin savaşın kaderine etki edecek kilit bir konumda olması dünya kamuoyunun dikkatini çekmesine sebep olmuştur. Bu yüzden savaş başladığı andan itibaren, Türk ve dünya basını bu konuyla yakından ilgilenmiş ve gelişmeleri kendi ülkelerine bildirmiştir. Amerikan basını da Çanakkale Cephesi’nde yaşanan gelişmeleri okuyucularına aktarmıştır. Birinci Dünya Savaşı’nın başlarında ABD’nin tarafsız bir ülke olması sebebiyle Amerikan basını her iki tarafta yaşanan gelişmeleri aktarmıştır. Çanakkale Savaşları’nda yaşanan gelişmelerin Amerikan basınında nasıl yer aldığı ve okuyuculara burada yaşanan olayların nasıl aktarıldığını incelemek bu çalışmanın asıl amacıdır. Bunun için Amerika’da yayımlanmış gazetelerin Çanakkale Savaşlarıyla ilgili yaptıkları haberler doküman analizi yöntemiyle incelenmiştir. Amerika basınında Çanakkale Savaşlarında Müttefik Devletlerin kazanmak için neredeyse her yola başvurdukları görülmektedir. Bu saldırılar karşında Türklerin ise büyük bir mücadele verdikleri görülmektedir.
The Effect of Phase Distribution on Imbibition Mechanisms for Enhanced Oil Recovery in Tight Reservoirs
Authors: Wang Mingyuan , Argüelles-Vivas Francisco J. , Abeykoon Gayan A. , Okuno Ryosuke
Published: August 2020

The main objective of this research was to investigate the impact of initial water on the oil recovery from tight matrices through surfactant-enhanced water imbibition. Two flooding/soaking experiments using fractured tight cores with/without initial water were performed. The experimental results were analyzed by the material balance for components: oil, brine, and surfactant. The analysis resulted in a quantitative evaluation of the imbibed fraction of the injected components (brine and surfactant).

Results show that the surfactant enhanced the brine imbibition into the matrix through wettability alteration. The initial efficiency of the surfactant imbibition increased when brine was initially present in the matrix. The imbibition of brine was more efficient with no initial water in the matrix. A possible reason is that the presence of initial water in the matrix was able to increase the initial efficiency of the surfactant imbibition; however, the increased amount of surfactant in the matrix lowered the interfacial tension between the aqueous and oleic phases; therefore, the efficiency of brine imbibition was reduced. Another possible reason is that capillary force was lower in the presence of initial water in the matrix, resulting in weaker imbibition of brine.

Although the two cases showed different characteristics of the mass transfer through fracture/matrix interface, they resulted in similar values of final water saturation in the matrix. Hence, the surfactant injection was more efficient for a given amount of oil recovery when there was no initial water in the matrix.
Effectiveness of oral health education on eight to ten year old school children in rural area of Magway Region, Myanmar
Authors: Swe Kyu Kyu , Soe Aung Kyaw , Aung Saw Htun , Soe Htin Zaw
Published: August 2020

Background

Oral diseases are common and widespread around the world. Many oral health problems are preventable and early onset is reversible. Myanmar faces many challenges in rendering oral health services and about 70 percent of total population resides in rural areas. These relate to the availability and accessibility of oral health services. Therefore, oral health education is one key element to prevent oral diseases and to promote oral health.

Methods

A quasi-experimental study was carried out at Basic Education Middle Schools in rural areas of Magway Township to study the effectiveness of oral health education on knowledge and behavior of eight to ten years old school children. A total of 220 school children, 110 from intervention school and 110 from control school, participated in this study from 2015 to 2017. Data for knowledge and behavior were collected before and after intervention in the two groups by using self-administered questionnaire. Tooth brushing method data were collected by direct observation with checklist. Oral health education was provided at eight weekly intervals for one year in the intervention group. After one year and six months, oral health knowledge and behavior were determined in the intervention group only to measure retention. Chi-square test, two samples t test, One way repeated measure ANOVA were used for data analysis. The study was approved by the Ethics Review Committee of University of Public Health in Yangon, Myanmar.

Results

There were significant differences between the two groups in oral health knowledge (p<0.05) except one and also in behavior (p<0.001) at after intervention. A positive effect of intervention was found in intervention group. The intervention had significant effect on sustainability of correct knowledge and behavior by the school children in intervention group although education session was stopped for six months after one-year education (p<0.001). Their mean knowledge and behavioral scores at three different points in time were (2.45±1.12 and 1.56±0.90) at baseline, (3.79±1.12 and 3.60±1.21) at one year after education, and (4.07±0.98 and 3.24±1.31) at six months after cessation of education, respectively.

Conclusion

The repeated oral health education was effective to promote and sustain oral health knowledge and behavior.
Perinatal listeriosis patients treated at a maternity hospital in Beijing, China, from 2013-2018
Authors: Li Chunyun , Zeng Huihui , Ding Xin , Chen Yi , Liu Xiaowei , Zhou Li , Wang Xin , Cheng Yumei , Hu Shanshan , Cao Zheng , Liu Ruixia , Yin Chenghong
Published: August 2020

Background: Listeriosis is a rare but severe foodborne infectious disease. Perinatal listeriosis is often associated with septicemia, central nervous system (CNS) infection, and serious adverse pregnancy outcomes (miscarriage and neonate death). Here we report the characteristics and outcomes of perinatal listeriosis cases treated over 6 years at Beijing Obstetrics and Gynecology Hospital (BOGH), the largest maternity hospital in China.

Methods: We retrospectively reviewed the records of laboratory-confirmed, pregnancy-associated listeriosis cases treated from January 1, 2013 to December 31, 2018. The clinical manifestations, laboratory results, perinatal complications and outcomes (post-natal follow-up of 6 months) were investigated.

Results: In BOGH, 12 perinatal listeriosis cases were diagnosed based on Listeria monocytogenes positive culture, including 10 single pregnancies and 2 twin pregnancies. The corresponding incidence of pregnancy-associated listeriosis was 13.7/100,000 deliveries. Among those cases, four pregnant women and four newborns had septicemia, and two of the neonates with septicemia also suffered CNS infection. All the maternal patients recovered. Two inevitable miscarriages and four fetal stillbirths occurred. Of the eight delivered newborns, six survived, and two died within 2 days from birth. None of the survivors had neurological sequelae during a 6-month follow-up. The overall feto-neonatal fatality rate was 57.1%; notably, this rate was 100% for infections occurring during the second trimester of pregnancy and only 14.3% for those occurring in the third trimester.

Conclusions: Perinatal listeriosis is associated with high feto-neonatal mortality, and thus, a public health concern. Additional large-scale studies are needed to strengthen the epidemiological understanding of listeriosis in China.
Socio-demographic Determinants of Low Sexual Desire and Hypoactive Sexual Desire Disorder: A Population-based Study in Iran
Authors: Hamzehgardeshi Zeinab , malary mina , moosazadeh mahmood , Khani Soghra , Pourasghar mehdi
Published: August 2020

Background: Various socio-demographic factors have been introduced as determinants of low sexual desire (LSD), but whether these variables can also contribute to hypoactive sexual desire disorder (HSDD) remains uncertain. In this study, we sought to identify the socio-demographic determinants of LSD and HSDD in Iranian women of reproductive age.

Methods: This was a population-based, cross-sectional study of 1000 Iranian women of reproductive age (15-49 years) who met the inclusion criteria. The participants were chosen using the systematic random sampling method from all the healthcare centers in Sari, Iran. LSD was defined as a score no higher than 33 on the Sexual Interest and Desire Inventory-Female (SIDI-F), sexually-related personal distress was considered as a score of at least 11.0 on the Female Sexual Distress Scale–Revised (FSDS-R), and HSDD was determined based on the sum of these scores. Descriptive statistics were used to describe the socio-demographic characteristics, while for analyzing grouped variables, Chi-squared test was run. Multivariate logistic regression test was also employed to adjust the effect of confounding variables.

Results: The mean score of sexual interest/desire among women was 30.6±10.5. After adjusting for the effect of confounding variables (socio-demographic variables such as age, age at first intercourse, level of education, etc.), logistic regression showed that age at first intercourse, length of marriage, and the level of satisfaction with income were significantly associated with both LSD and HSDD (P<0.01). In addition, advancing age (P<0.001) and body mass index (P<0.01) were predictors of LSD alone.
Conclusion: Some socio-demographic factors could predict LSD in women, while they were not associated with HSDD. In other words, some factors associated with LSD do not instigate personal distress, which is one of the criteria necessary for the diagnosis of HSDD.
Breastfeeding cessation in the era of Elimination of Mother to Child Transmission of HIV in Uganda: a retrospective cohort study
Authors: Ngbapai Jackslina Gaaniri , Izudi Jonathan , Okoboi Stephen
Published: August 2020

Background: Breastfeeding an infant exposed to HIV carries the risk of HIV acquisition whilst not breastfeeding poses higher risk of death from malnutrition, diarrhea, and pneumonia. In Uganda, mothers living with HIV are encouraged to discontinue breastfeeding at 12 months but data are limited. We examined the frequency and factors associated with cessation of breastfeeding at one year among mothers living with HIV at Ndejje Health Center IV, a large peri-urban health facility in Uganda.Methods: This retrospective cohort study involved all mothers living with HIV enrolled in HIV care for ≥12 months between June 2014 and June 2018. We abstracted data from registers, held focus group discussions with mothers living with HIV and key informant interviews with healthcare providers. Cessation of breastfeeding was defined as the proportion of mothers living with HIV who had discontinued breastfeeding at one year. We summarized quantitative data descriptively, tested differences in outcome using Chi-square and t-tests, and established independently associated factors using modified Poisson regression analysis at 5% statistical significance level. We thematically analyzed qualitative data to enrich and triangulate the quantitative results. Results: Of 235 participants, 150 (63.8%) had ceased breastfeeding at one year and this was independently associated with the infant being female (Adjusted risk ratio (aRR): 1.25, 95% confidence interval (CI), 1.04, 1.50), the mother being multiparous (aRR, 1.26; 95%CI, 1.04-1.53), and the initiation of breastfeeding being on the same-day as birth (aRR, 0.06; 95%CI, 0.01-0.41).The reasons for ceasing breastfeeding included male infants over breastfeed than females, maternal literacy and knowledge adequacy about breastfeeding, support and reminders from the partner, and boys can bite once they get teeth. Conversely, the reasons for not ceasing to breastfeed encompassed insufficient knowledge about breastfeeding and girls feed a bit less.Conclusion: Suboptimal proportion of infants were ceased from breastfeeding at one year and this might increase the risk of mother to child transmission of HIV. Cessation of breastfeeding was more likely among female infants and multiparous mothers but less likely when breastfeeding was initiated on same-day as birth. Interventions to enhance cessation of breastfeeding should target groups of mothers with lower rates.
Adherence to World Health Organisation guidelines for treatment of early onset neonatal sepsis in low-income settings; a cohort study in Nepal
Authors: Ekman Beatrice , Paudel Prajwal , Basnet Omkar , Ashish KC , Wrammert J.
Published: August 2020

Background

Neonatal sepsis is one of the major causes of death during the first month of life and early empirical treatment with injectable antibiotics is a life-saving intervention. Adherence to World Health Organisation guidelines on first line antibiotics is crucial to mitigate the risks of increased antimicrobial resistance. The aim of this paper was to evaluate if treatment of early onset neonatal sepsis in a low-income facility setting observe current guidelines and if compliance is influenced by contextual factors.

Methods

This cohort study used data on antimicrobial treatment of neonatal sepsis onset within 72 hours of life from 12 regional hospitals participating in a scale-up trial of a neonatal resuscitation quality improvement package intervention in Nepal. Infants treated according to guidelines were compared with those receiving other antimicrobials. A multiple logistic regression analysis adjusted for the intervention and time trend was applied.

Results

1,564 infants with a preliminary diagnosis of early onset sepsis were included. A majority (74.9%) were treated according to guidelines and adherence was increasing over time. Infants born at larger facilities (adjusted Odds Ratio 5.6), those that were inborn (adjusted Odds Ratio 1.97) or belonging to a family of dis-advantaged caste (adjusted Odds Ratio 2.15) had higher odds for treatment according to guidelines. A clinical presentation of lethargy or tachypnoea was associated with adherence to guidelines.

Conclusion

Adherence to guidelines for antibiotic treatment of early neonatal sepsis was moderately high in this low-income setting. Odds for observing guidelines increased with facility size, for inborn infants and if the family belonged to a dis-advantaged caste. Cefotaxime was a common alternative choice when guidelines were not followed, highly relevant for the risk of increased antimicrobial resistance.
Three-dimensional printing technology for localised thoracoscopic segmental resection for lung cancer : a quasi-randomised clinical trial
Authors: Chen Yangming , Zhang Jiguang , Chen Qianshun , Li Tian , Chen Kai , Yu Qinghua , Lin Xing
Published: August 2020

Background : Three-dimensional (3D) computed tomography (CT) reconstruction technology has gained increasing attention owing to its potential in locating ground glass nodules in the lung. The 3D printing technology additionally allows the visualisation of the surrounding anatomical structure and variations. However, the clinical utility of these techniques is unknown. This study aimed to establish a lung tumour and an ana tomical lung model using 3D printing and 3D chest CT reconstruction and to evaluate the clinical potential of 3D printing technology in uniportal video-assisted thoracoscopic segmentectomy . Methods : Eighty-nine patients with ground glass nodules who underwent uniportal video-assisted thoracoscopic segmentectomy were classified into the following groups: Group A, lung models for pre-positioning and simulated surgery that were made with 3D chest CT reconstruction and 3D printing; Group B, patients who underwent chest CT scans with image enhancement for 3D reconstruction. The differences in the surgery approach transfer rate, surgical method conversion rate, operative time, intraoperative blood loss, and postoperative complication rate were compared between the groups. Results : The surgery approach transfer rate was 0% and 10.5% for Groups A and B, respectively, showing a significant difference (p=0.030); the operative time was 2.07±0.24 hours and 2.55±0.41 hours, respectively, indicating a significant difference (p<＜0.001); intraoperative blood loss volume was 43.25±13.63 and 96.68±32.82 mL, respectively, demonstrating a significant difference (p<＜0.001); the postoperative complication rate was 3.9% and 13.2%, respectively, showing a non-significant difference (P=0.132). The rate of surgical method conversion to lobectomy in Group A was 0%, which was significantly lower than that of 10.5% in group B (p<0.030). Conclusions : 3D printing technology facilitates a more accurate location of nodules by surgeons, as it is based on two-dimensional and 3D imaging findings, thereby improving the accuracy and safety of surgery. This technique is worth applying in clinical practice.
Wild-type cutoff for Apramycin against Escherichia coli
Authors: Yang Yuqi , Xiao Tianshi , Li Jiarui , Cheng Ping , Li Fulei , Yu Hongxiao , Liu Ruimeng , Muhammad Ishfaq , Zhang Xiuying
Published: August 2020

Background：Apramycin is used exclusively for the treatment of Escherichia coli (E.coli) infections in swine around the world since the early 1980s. Recently, many research papers have demonstrated that apramycin has significant in vitro activity against multidrug-resistant E.coli isolated in hospitals. Therefore, ensuring the proper use of apramycin in veterinary clinics is of great significance of public health. The objectives of this study were to develop a wild-type cutoff for apramycin against E.coli using a statistical method recommended by Clinical and Laboratory Standards Institute (CLSI) and to investigate the prevalence of resistance genes that confer resistance to apramycin in E. coli.Results: Apramycin susceptibility testing of 1230 E.coli clinical isolates from swine were determinded by broth microdilution testing according to the CLSI document M07-A9. A total number of 310 E.coli strains from different minimum inhibitory concentration (MIC) subsets (0.5-256 µg/mL) were selected for the detection of resistance genes (aac(3)-IV; npmA; apmA) in E. coli by PCR. The percentage of E. coli isolates at each MIC (0.5, 1, 2, 4, 8, 16, 32, 64, 128, and 256 µg/mL) was 0.08%, 0.08%, 0.16%, 2.93%, 31.14%, 38.86%, 12.85%, 2.03%, 1.46%, and 10.41%. The MIC50 and MIC90 were 16 and 64 µg/mL. All the 310 E.coli isolates were negative for npmA and apmA gene, and only the aac(3)-IV gene was detected in this study.Conclusions: The wild-type cutoff for apramycin against E.coli was defined as 32 µg/mL. The prevelance of aac(3)-IV gene mainly concentrated in these MIC subsets ‘MIC ≥ 64 µg⁄ mL’, which indicates that the wild-type cutoff established in our study is reliable. The wild-type cutoff offers interpretion criteria of apramycin susceptibility testing of E.coli.
Factors associated with anxiety and depression in rheumatoid arthritis patients: A cross-sectional study
Authors: Uda Miyabi , Hashimoto Motomu , Uozumi Ryuji , Torii Mie , Fujii Takao , Tanaka Masao , Furu Moritoshi , Ito Hiromu , Terao Chikashi , Yamamoto Wataru , Sugihara Genichi , Nakagami Yukako , Mimori Tsuneyo , Nin Kazuko
Published: August 2020

Background Management of anxiety and depressive symptoms in rheumatoid arthritis (RA) patients is vital. Previous studies investigating this topic are conflicting, and this topic still has not been thoroughly investigated. This study aimed to clarify the association of disease activity with anxiety and depressive symptoms after controlling for physical disability, pain, and treatment.Methods We conducted a cross-sectional study of RA patients from the Kyoto University Rheumatoid Arthritis Management Alliance cohort. For assessments, we used the Disease Activity Score (DAS28), Health Assessment Questionnaire Disability Index (HAQ-DI), and Hospital Anxiety Depression Scale. Depression and anxiety were defined by a Hospital Anxiety Depression Scale score ≥8. We then performed multivariable logistic regression analyses.Results Of 517 participants, 17.9% had anxiety and 28.2% had depression. The multivariable logistic regression analyses showed that DAS28-based non-remission was not statistically associated with anxiety symptoms (odds ratio [OR] [95% confidence interval {CI}], 0.93 [0.48–1.78]: p = 0.82) and depressive symptoms (OR [95% CI], 1.45 [0.81–2.61]: p = 0.22). However, severity of the patient’s global assessment (PtGA) on DAS28 was associated with anxiety symptoms (OR [95% CI], 1.15 [1.02–1.29]; p = 0.03) and depressive symptoms (OR [95% CI], 1.21 [1.09–1.35]; p < 0.01). Additionally, HAQ-DI-based non-remission was associated with anxiety symptoms (OR [95% CI], 3.51 [1.85–6.64]; p < 0.01) and depressive symptoms (OR [95% CI], 2.65 [1.56–4.50]; p < 0.01). Patients using steroids had a closer association with depressive symptoms than those not using them (OR [95% CI], 1.66 [1.03–2.67]; p = 0.04).Conclusions As per the multivariable logistic regression analysis, there was no association between DAS28-based-non-remission and anxiety and depressive symptoms; however, the univariate analysis revealed such association. In the multivariate analysis, PtGA and non-remission on HAQ were associated with anxiety and depressive symptoms. Rather than focusing solely on controlling disease, activity and treatment should focus on improving or preserving physical function and patient's overall sense of well-being.
Combined support mechanism of rock bolt and anchor cable for adjacent roadways in the external staggered split-level panel layout
Authors: Batugin Adrian , Wang Zhiqiang , Lv Wenyu , Su Zehua , Sidikovna Shermatova Sayyora
Published: August 2020

Utilizing the spatial structure characteristic of the external staggered split-level panel layout, the combined support technology of adjacent roadways was proposed, and combined support mechanism of rock bolt and anchor cable was analyzed. The influence of side rock bolt and anchor cable parameters respectively on mechanical properties of the anchorage body and support stress distribution of lateral coal body were revealed through FLAC 3D software. The optimal support parameters of side rock bolt and anchor cable were determined subsequently. And the support effect of the gob-side entry under mining influence was verified. Result shows that the support of side rock bolt and anchor cable can improve mechanical properties and the stress state of the anchorage body, which has a good protective effect on the coal body of the air-intake entry roof and side wall. It is beneficial to the stability of the side wall and the realization of the suspension effect for the roof rock bolt and anchor cable, which makes the surrounding rock maintenance of the gob-side entry of the thick coal seam more favorable.