bluuebunny/crossref_metadata_2025 huggingface dataset:
Autismus-Spektrum-Störungen bei Erwachsenen
Authors: Riedel Andreas , Clausen Jens
Published: July 2022

Hochfunktionaler Autismus bei Erwachsenen: therapeutisches Grundwissen

Autismus-Spektrum-Storungen werden vor allem als eine Entwicklungsstorung bei Kindern wahrgenommen. Es liegt aber in ihrer Natur, dass sie in späteren Lebensphasen andauern.

Das vorliegende Buch gibt einen kompakten Überblick über Ausprägungen, Diagnostik und Therapie von Autismus im Erwachsenenalter und hilft psychiatrisch, psychotherapeutisch und psychosozial Tätigen bei der Begegnung und den Umgang mit erwachsenen und auch möglicherweise nicht diagnostizierten Autisten.

Praxisnah reflektieren zwei ASS-Experten die vorherrschenden Konzepte von Krankheit, Störung und Behinderung und bieten so einen überaus produktiven Zugang zu den Lebenswelten von Autisten, ihren Schwierigkeiten und Ressourcen. Sozialrechtliche Informationen und konkrete Hilfen für schwierige Therapiesituationen im Umgang mit Erwachsenen mit einer hochfunktionalen Autismus-Spektrum-Störung runden den Band ab.
Umgang mit zwangserkrankten Menschen
Authors: Fricke Susanne
Published: July 2022

Menschen mit einer Zwangserkrankung bringen ihre therapeutischen Helfer nicht selten »auf die Palme«. Strapaziert wird nicht nur die Geduld im Umgang miteinander, sondern der Helfer ist immer wieder gefordert, seine eigenen Werte und Normen zu reflektieren und auch zu diskutieren. Deshalb hält sich hartnäckig die Ansicht, dass diese Erkrankung schwer zu behandeln sei. Dieses Basiswissen rückt, neben umfassenden Informationen über Zwangserkrankungen, auch die positiven Seiten dieser als schwierig geltenden Patientengruppe ins Blickfeld. Der Schwerpunkt liegt auf der Vermittlung von Aspekten, die für die praktische Arbeit mit Zwangserkrankten wichtig sind: motivieren, abgrenzen, stärken.

Klar, systematisch und in komprimierter Form werden an vielen Beispielen Erscheinungsformen von Zwangserkrankungen geschildert und Wege gezeigt, wie man konstruktiv mit ihnen umgehen kann, ohne sich selbst nerven zu lassen.
Die abklingende Psychose
Authors: Schlimme Jann , Brückner Burkhart
Published: July 2022

Psychoseerfahrungen gehen oft mit tiefgreifenden Verunsicherungen und Ängsten, aber auch mit Symptomen wie Wahn oder Halluzinationen und einem sozialen Rückzug einher. Dies wirkt auf alle Beteiligten befremdlich. Mit diesem Buch bauen die Autoren eine Brücke auf dem Weg zur Verständigung. Ihr Modell der abklingenden Psychose bietet Orientierung und Anleitung für das gemeinsame Handeln in Krisen, im Alltag und der Therapie. Das in gemeinsamer Forschung mit psychoseerfahrenen Personen entwickelte lebensweltliche Modell der Genesung beschreibt die grundsätzliche Haltung und das konkrete Handwerkszeug für die gesundheitsfördernde Begleitung der Betroffenen.

Die klassische Krankheitslehre hat die Frage, wie Psychosen abklingen, vernachlässigt und damit dazu beigetragen, dass psychiatrische Behandlung vielfach auf die Gabe von Psychopharmaka reduziert scheint. Aber auch aktuelle Recoveryansätze bilden den Weg zur Genesung und Gesundung häufig noch zu global ab. Dieses Buch bietet ein neuartiges Modell der entscheidenden Wendepunkte und Stufen im Genesungsprozess. Psychosen klingen ab und Genesung gelingt, wenn geeignete Sozialräume, gemeinsame Erzählungen und non-verbale »Abschalttechniken« entwickelt werden können. Es geht darum, die Lebenswelt und Bedürfnisse psychoseerfahrener Menschen besser zu verstehen und schrittweise Möglichkeiten der Verständigung aufzubauen, um den Weg der Genesung bestmöglich zu begleiten. Die Autoren zeigen mit zahlreichen Begleitbeispielen, wie dies möglich ist und alle Beteiligten dazu aktiv beitragen können.
Die Vermessung der Psychiatrie
Authors: Weinmann Stefan
Published: July 2022

Wie sieht es aus mit der sogenannten »Evidenz« zu den Ursachen von Depression und Schizophrenie? Wie mit der Wirksamkeit von Medikamenten und Psychotherapien? Welche Bedeutungen haben Vorurteile, Verzerrungen und sich selbst erfüllende Voraussagen in der psychiatrischen Behandlung und Forschung? Und wieso helfen viele gut erforschte Ansätze so häufig nicht?

Wenn man die gegenwärtige Psychiatrie verstehen will, muss man verstehen, was in den Köpfen von Psychiater*innen vor sich geht, sagt Weinmann und plädiert dafür, dass sich die Psychiatrie mehr den sozialen und auch den gesellschaftlichen Bedingungsfaktoren stellt. Mit diesem Buch liefert er einen kritischen und hochspannenden Beitrag.
Normalität
Authors: Finzen Asmus
Published: July 2022

Welche normativen Konzepte liegen psychischer Gesundheit und Krankheit zugrunde? Was ist eigentlich »normales« Verhalten?

Ausgrenzungsphänomene sind in der Gesellschaft an vielen Stellen zu beobachten. Die Begriffe »normal« und »nicht normal« stehen oft für »nachvollziehbar« und »unverständlich«, aber auch für »seelisch gesund« und »psychisch krank«.

Asmus Finzen zeigt auf, wie sehr die Vorstellungen sowohl in der Gesellschaft als auch in psychiatrischen Argumentationen zutiefst von Normalitätsannahmen geprägt sind. Von der Soziologie ausgehend, arbeitet er sich über unser Verständnis von Gesundheit und Krankheit vor zur Psychiatrie – erhellend, gründlich, manchmal angriffslustig.
Klienten motivieren
Authors: Sachse Rainer , Langens Thomas A. , Sachse Meike
Published: July 2022

Vom Willen zur Tat!

Änderungsbereitschaft und Stabilisierungstendenzen stehen sich in jeder Therapie gegenüber. Aufgabe von Therapeuten ist es, Motivationsprobleme zu identifizieren und den Willen zur Veränderung zu fördern.

Das Autorenteam beschreibt häufige Motivationsblockaden und stellt prinzipielle Strategien zur Motivationssteigerung vor. Die Entschlossenheit, Entscheidungen auch umzusetzen, nimmt zu, wenn die zentralen Ziele des Klienten angesprochen und die »Kosten« und »Gewinne« einer Veränderung genau analysiert werden.

Zur »Energetisierung« von Klienten eignen sich insbesondere zwei Motivierungstechniken, die ausführlich vorgestellt werden: das Ein-Personen- Rollenspiel sowie die Pro-und-Kontra-Diskussion. Beispiele aus der Praxis und kommentierte Transkripte von Therapiesitzungen zeigen, wie auch in scheinbar festgefahrene Situationen Bewegung kommen kann.
Jobcoaching für Menschen mit psychischer Erkrankung
Authors: Bärtsch Bettina , Huber Micheline
Published: July 2022

Es zeigt sich immer mehr, dass viele Menschen mit einer psychischen Erkrankung auf dem ersten Arbeitsmarkt arbeiten wollen und dies auch können, wenn sie von Jobcoaches unterstützt werden. Dieses Buch vermittelt praxisorientierte Ideen für die tägliche Arbeit als Jobcoach.

Anhand vieler Beispiele identifizieren die Autorinnen zentrale Themen der Klient*innen und geben Tipps für die Beziehungsgestaltung. Wie gelingt die Vermittlung auf Arbeitsplätze, wie mit Ängsten umgehen? Wie solltengemeinsame Gespräche mit den Arbeitgeber*innen ablaufen und wie vorbereitet werden? Aber auch die ganz besonderen Herausforderungen

des Berufsbildes werden beschrieben, immer mit den nötigen praktischen Hinweisen versehen.
Experten für Eigensinn
Authors: Becker Jo , Schlutz Daniela
Published: July 2022

Wie gelingen Rehabilitation und Recovery bei Menschen mit herausforderndem Verhalten?

20 ehemalige »Experten für Eigensinn« beschreiben ihren Weg, Fachkräfte und Angehörige schildern den Verlauf aus ihrer Sicht. So ist eine Sammlung von Beispielen guter Gemeindepsychiatrie entstanden, berichtet von Praktikern und Experten aus Erfahrung.

In einem fachlichen Teil werden einfache und effektive Methoden vorgestellt, die sich in der Zusammenarbeit mit »schwierigen Klienten« bewährt haben. Dazu gehören Kommunikationstechniken zur Entwicklung einer empathischen Beziehung, Biografiearbeit, Selbstachtsamkeit und die Netzwerkmethoden »Runder Tisch« und »Konsultationsverbund«.
Die Assistenzleistung
Authors: Konrad Michael
Published: July 2022

Sozialhilfeleistungen werden Rehabilitationsleistungen

Das Bundesteilhabegesetz (BTHG) soll Menschen mit wesentlichen Teilhabeeinschränkungen ein möglichst selbstbestimmtes Leben ermöglichen. Die Fachleistungen werden dazu künftig unabhängig von der Wohnform erbracht. Die Betroffenen erhalten ab 2020 Assistenzleistungen der Eingliederungshilfe, entsprechend ihrem individuellen Hilfebedarf.

Diese kompakte Einführung beantwortet mit vielen Beispielen Fragen nach der zukünftigen Gestaltung der mobilen Unterstützung im Sozialraum und in betreuten Wohnangeboten.
Safewards
Authors: Löhr Michael , Schulz Michael , Nienaber André
Published: July 2022

Prävention von Konflikten und Gewalt

Das Safewards-Modell bietet nicht nur eine Erklärung für die Entstehung und Eskalation von Konflikten auf Station, sondern auch konkrete Interventionen zu ihrer Prävention. Erfahrungen aus dem deutschsprachigen Raum zeigen die Praktikabilität für verschiedene Settings der Akutpsychiatrie, der Suchtbehandlung, der Forensik und der Kinder- und Jugendpsychiatrie auf, aber auch die Fallstricke bei der Implementierung.

Safewards wird da erfolgreich umgesetzt, wo die verschiedenen Berufsgruppen einbezogen werden und die Leitung den Einführungsprozess unterstützt. Die Verbesserung von Kommunikation, Beziehungsgestaltung und Milieu braucht das gesamte Team und die Patient*innen – sie kommt allen zugute.

Die Reihe »better care« setzt Standards für Ausbildung und berufliche Praxis in der psychiatrischen Pflege.
Motivierende Gesprächsführung in der Psychiatrie
Authors: Kremer Georg , Michael Michael
Published: July 2022

Entschieden gegen die Unentschlossenheit

Es ist eine alltägliche Erfahrung, dass Klientinnen und Klienten therapeutische Maßnahmen nicht oder nur teilweise umsetzen. Wenn zunächst vereinbarte Ziele später nicht eingehalten werden, kann es sein, dass im Vereinbarungsprozess nicht alle relevanten Motive berücksichtigt wurden und nicht erkannte Ambivalenzen im Spiel waren. Ein erfolgreiches Kommunikationskonzept sorgt in diesen Situationen für Klarheit und Entschlossenheit!

Dieses Buch nimmt klassische akutpsychiatrische Situationen in den Fokus. Konkrete Beispiele zeigen: Ob es um das Gestalten von Beziehungen geht, soziale Probleme, das Einhalten von Regeln, die Einnahme von Medikamenten oder auch um Suizidalität – mit den Grundelementen und Strategien der Motivierenden Gesprächsführung lassen sich Widerstände aufgreifen und gemeinsam getragene und erreichbare Ziele finden.
Existenzieller Umgang mit Trauer und Verlusten
Authors: Ohls Isgard , Kaiser Peter
Published: July 2022

Spiritualität als heilende Ressource

Fachleute im psychosozialen Bereich werden immer wieder mit Fragen nach dem Sinn des Lebens konfrontiert und suchen nach einem sicheren Umgang mit Verlusten, Tod und Trauer. Wenn Helfende das heilsame Potenzial von Spiritualität und die Ressourcen der jeweiligen religiösen oder philosophischen Weltanschauung nutzen möchten, müssen sie jedoch wissen, wie die verschiedenen Traditionen mit dem Thema umgehen.

Das Buch macht u. a. vertraut mit den Weltreligionen, den philosophischen Schulen Asiens und neueren religiösen Bewegungen. Auch die Trauer bei Menschen mit einer atheistischen oder agnostischen Haltung wird thematisiert.
Beziehungsdynamiken besser verstehen
Authors: Lütjen Reinhard
Published: July 2022

Von Freud bis Fonagy: Tiefenpsychologisches Wissen nutzen

Im Hintergrund psychischer Beeinträchtigungen stehen immer auch spezielle psychodynamische Einflussfaktoren. Zu lange ist dieses Wissen in der psychiatrischen Arbeit nicht beachtet worden, dabei bietet es gerade für den Beziehungsaufbau und die Vermeidung von Beziehungsabbrüchen mit psychisch erkrankten Menschen viele praktische Ansatzpunkte.

In diesem Buch werden nicht nur die psychodynamischen Modelle und Mechanismen im Überblick vorgestellt, auch die wichtigsten Störungsgruppen werden aus dieser Perspektive beleuchtet. Zahlreiche Praxisbeispiele machen deutlich: Wer tiefenpsychologische Dynamiken erkennt und versteht, kann besser mit erkrankten Menschen in Kontakt treten und bleiben.
Cytotoxic Effects of Rheum khorasanicum Extract on MCF-7 Human Breast Cancer Cell Line and ODC1 Gene Expression
Authors: Noori Zeinab , Safipour Afshar Akbar
Published: July 2022

Background: Polyamine metabolism has a critical role in cancer initiation and progression. The abnormal overexpression of the ornithine decarboxylase (ODC1) enzyme gene could be a characteristic of cancer cells. Objectives: The current study evaluated the cytotoxic effects of Rheum khorasanicum extract in three different solvents, including distilled water, ethanol, and n-hexane, on the MCF-7 breast cancer cell line and assessed the expression level of the ODC1 gene upon the abovementioned treatments. Methods: We cultured MCF-7 cancer cells in complete cell culture media and subsequently subjected them to increasing concentrations (0 - 200 μg/mL) of the extract. The cytotoxic activity of the extract was investigated using an MTT assay. The quantitative analysis of ODC1 gene expression was performed using real-time PCR. Results: The cell viability was significantly decreased in concentration- and time-dependent manners. The mRNA expression of the ODC1 gene declined gradually with the increasing concentrations of extracts. Conclusions: Our findings indicated that R. khorasanicum extract could potentially influence ODC1 gene expression in breast cancer cells and exert inhibitory effects on cancer cell proliferation.
Located in Space
Authors: Campbell Douglas R. ,   Philosophy Documentation Center
Published: July 2022

I argue that Plato thinks that the soul has location, surface, depth, and extension, and that the Timaeus’ composition of the soul out of eight circles is intended literally. A novel contribution is the development of an account of corporeality that denies the entailment that the soul is corporeal. I conclude by examining Aristotle’s objection to the Timaeus’ psychology and then the intellectual history of this reading of Plato.
Corona Observations
Authors: Boys-Stones George ,   Philosophy Documentation Center
Published: July 2022

Aetius 2.24.1 includes a reference to the ‘corona’ apparent during a total solar eclipse, and suggests a theory, also discernible in Plutarch, that it is a case of the optical phenomenon known as a ‘halo.’
Análise comparativa da certificação: o caso de GlobalGAP, Comércio Justo, Produção Integrada de Frutas e Orgânico
Authors: Dorr Andrea Cristina
Published: July 2022

Certificação tem se tornado relevante como um sinal de comercialização especialmente no setor de frutas ao longo dos últimos anos. Muitas cadeias estão certificadas por sistemas como GlobalGAP, Comércio Justo, Produção Integrada de Frutas e Orgânico. Ao mesmo tempo, em países desenvolvidos, particularmente como a União Européia e os Estados Unidos, a demanda por níveis mais elevados de segurança do alimento tem levado a implantação de sistemas de certificação que relaciona atributos de segurança do alimento e impõe requerimentos mais restritos. A análise comparativa dos quatro sistemas de certificação que existem no setor de frutas no Brasil tem mostrado que o GlobalGAP e o Produção Integrado de Frutas (PIF) são similares. No entanto, eles diferem em relação ao número de requerimentos a respectiva distribuição ao longo dos estágios. Ao contrário de PIF e GlobalGAP, o Comércio Justo foca na associação de pequenos produtores e cooperativas e não em produtores individuais. Em relação à certificação orgânica, os requerimentos não são direcionados para um produto em particular ou cultura e seus níveis de requerimentos não são mencionados.
Redefining the Role of Ketamine for Topicalisation and its Comparison with the Legend Lignocaine for OesophagogastroduodenoscopiesA Randomised Clinical Study
Authors: Pathak Bhumika , Panchal Nirali , Mevcha Sunny R , Chaudhari Madhavi
Published: July 2022

Introduction: Endoscopy is a minimally invasive procedure for visualisation of gastrointestinal tract performed under topicalisation with or without sedation. Lignocaine is one of the most popular local anesthetic used for topicalisation for endotracheal intubation in different forms like spray, gargles, nebulisation, gel. Recently ketamine has emerged as an effective antinociceptive and anti-inflammatory agent. Aim: To observe and compare the effect of ketamine and lignocaine gargles for decreasing sore throat, coughing and change in voice. Also to observe various side-effects following use of ketamine and lignocaine. Materials and Methods: This prospective double-blind randomised clinical trial was conducted at Shree Krishna Hospital, Karamsad, Gujarat, India, from January 2020 to June 2021. Total 70 patients undergoing oesophagogastroduodenoscopies under sedation were included in the study. They were divided into two groups i.e, 35 patients in each group. Group L received lignocaine 2% viscous gargles 3 mg/kg and group K received ketamine gargles 3 mg/kg ideal body weight diluted in Normal Saline (NS) up to total 30 mL. Sore throat, coughing, change in voice, side effects were observed. Student’s t-test was used for continuous data. Results: In group L, 11.4% of patients and in group K 22.9% of patients complained of mild sore throat (grade 1) immediate postprocedure but this was statistically insignificant (p-value=0.2). For both the groups, grade 1 coughing was observed in 2.9% patients (p-value >0.995). In both the groups 5.71% of patients complained about change of voice, statistically insignificant (p-value >0.995). Vomiting was observed as a side-effect in 2.9% of patients but there were no other side-effects. Conclusion: Gargling with ketamine was as effective as lignocaine for prevention of sore throat, coughing and change in voice in patients undergoing oesophagogastroduodenoscopies and thus improved patient compliance.
Pattern of Bacterial Isolates in Patients with Nasolacrimal Passage Obstruction and their Antibiotic Sensitivity Pattern in a Tertiary Care Teaching Hospital, Pune, India
Authors: Dhore Nilay , Prasad Shashi Prabha , Tendulkar Karishma , Ahuja Amod , Patil Mayur , Naik Kunj
Published: July 2022

Introduction: An acquired Nasolacrimal Duct Obstruction (NLDO) can occur at any age, and is classified as either primary or secondary. The nasolacrimal obstruction occurring primarily also known as Primary Acquired Nasolacrimal Duct Obstruction (PANDO) is observed mainly in conditions occurring due to inflammation or fibrosis. Aim: To study the current pattern of bacterial isolates with nasolacrimal passage obstruction and their antibiotic sensitivity patterns. Materials and Methods: This was a cross-sectional study conducted in the Department of Ophthalmology at Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India, over the period of two years from November 2019 to November 2021. A total of 100 patients were selected for the study. All the patients coming to Ophthalmology Out-patient Department (OPD) with the complaints of epiphora discharge, or both along with regurgitation on pressure over lacrimal sac and mucoid or mucopurulent or clear regurgitant material on sac syringing were taken. Before the beginning of the investigative procedure, informed consent was taken. The Clinical and Laboratory Standards Institute’s (CLSI) standardised Kirby-Bauer disc diffusion test was used to determine antibiotic susceptibility. Results: In the present study, the distribution of patients according to bacterial isolates was as follows, a maximum of 62% of patients were found with no growth while 18% methicillinsensitive Staphylococcus aureus (MSSA), 10% Coagulasenegative staphylococci (CoNS), 6% Streptococcus pneumoniae (S. pneumoniae), 4% Pseudomonas were observed respectively. In present study, CoNS was observed as the predominant bacterial isolate in the diabetics with a female preponderance followed by MSSA (39%), Pseudomonas (75%), and S. pneumoniae (33%). This study found ciprofloxacin as a broad-spectrum antibiotic that worked against most bacterial isolates. Conclusion: A higher female preponderance was observed in this study with the left side being affected in most of the patients. The pattern of antibiotic sensitivity varies from region to region and thus should be kept in mind while prescribing antimicrobial therapy to the patients.
To Study the Marketing Efficiency of Apple (Malus domestica) in Kullu District of Himachal Pradesh
Authors: Guleria Ajay , Kumar Sanjay , Singh Vikas
Published: July 2022

The present study investigate the efficiency of marketing of Apple in Kullu district of Himachal Pradesh. Kullu district was purposively selected for the study as apple is primarily grown crop in the district. The sample drawn for the study comprised of 100 apple growers of Kullu and Naggar blocks. The various analytical tools were used to analyse the efficiency of marketing channels of apple. The marketing channels involves in the study area is three in number, channel I (Producer– Retailer–Consumer) was the most effective channel as it had the highest marketing efficiency index of 2.28. Majority 18 per cent of the growers marketed apple through channel II (Producer– Wholesaler–Retailer–Consumer). The price spread was the lowest (Rs. 397.9) in channel I (Producer–Retailer–Consumer); and accordingly, the producer’s share in final consumer rupee was the highest (69.57 %) in channel I.
The Effect of Fasting Ramadan on Diabetic Patients with High Risk of Cardiovascular Disease
Authors: Murad Rania ALsayed , ALakkad Ashraf , Adwan Anwar , Hussein Mohamed El , Mohammed Noor Ullah Hussaini , Jamaluddeen Nawwar Burhan
Published: July 2022

One of the common questions for patients with a history of cardiovascular disease is whether it is safe for them to fast during Ramadan. Yet, studies on the effects of Ramadan fasting on blood lipids, blood pressure, anthropometric parameters and other cardiovascular risk factors are scarce, and have given inconclusive results. The aim of this study is to investigate the effect of Ramadan fasting on cardiovascular risk factors including biochemical indices, blood pressure and main anthropometric parameters. This Prospective observational study was conducted at the CCU (Coronary care unit) and medical wards of Madinat Zayed hospital one of Al Dhafra hospitals, under Seha Abu Dhabi. Fifty-Six diabetic patients admitted with cardiovascular events including 48 males and 8 females with a previous history of cardiovascular event completed the study. Their age ranged between 32 and 91 years with a mean of 54.0 ± 10 years. A non-significant slight biochemical modification with regard to the metabolic profile pre, during and post-Ramadan period was reported: eGFR, total cholesterol, LDL, and HDL were increased yet, triglycerides and creatinine were non-significantly lower during Ramadan. Findings also showed a non-significant decrease in the post Ramadan blood pressure values which could be attributed to the metabolic switch.
Effect of Different Varieties, Nitrogen Levels and Cutting Management on Yield and Its Attributes of Fodder Bajra (Pennisetum glaucum L.)
Authors: Anoohya D. , Balazzii Naaiik R. V. T. , Rekha K. Bhanu , Kumar T. Sukruth , Shashikala T. , Yakadri M.
Published: July 2022

Aims: To identify an ideal pearl millet variety under ideal nitrogen level and cutting management for high green fodder yield and dry fodder yield.

Study Design: Factorial Randomized block design.

Place and Duration of Study: AICRP on Forage Crops and Utilization, Agricultural Research Institute, from July 2021 and Nov 2021.

Methodology: Field experiment was conducted at AICRP on Forage Crops and Utilization, ARI, Rajendranagar, Hyderabad during kharif 2021. The treatments consisted of three varieties (TSFB 15-4, TSFB 15-8 and Moti bajra), three nitrogen levels (80, 100 and 120 kg N ha-1) and two cutting management practices (C1: Two cuts: 1st at 60 days after sowing (DAS), 2nd cut at 50% flowering) (C2: Three cuts: 1st at 50 days after sowing (DAS), 2nd cut at 35 days after 1st cut and 3rd cut at 50% flowering) laid out in randomized block design with factorial concept, with Factor (A) as varieties, Factor (B) as nitrogen levels and Factor (C) as cutting management with three replications. The soil was sandy loam in texture with pH of 7.0 low in available nitrogen, medium in available phosphorus and available potassium.

Results: Variety TSFB 15-8 recorded significantly higher plant height (67.2 cm) and leaf-stem ratio (0.4) green forage yield (821.1 q ha-1), dry fodder yield (198.4 q ha-1)respectively, but Moti bajra variety was recorded highest number of tillers m-2 (4.5).Application of nitrogenat the rate of 120 kgha-1 significantly recorded highest plant height (72.0 cm), number of tillers m-2 (4.7) and leaf-stem ratio (0.4), green forage yield (817.7 q ha-1), dry fodder yield (201.0 q ha-1). Three cuts for green fodder recorded significantly higher plant height (65.9 cm), number of tillers (5.1) and leaf-stem ratio (0.5) green fodder yield(910.0 q ha-1), dry fodder yield (216.4 q ha-1) compared to two cuts.

Conclusion: Variety TSFB 15-8 with nitrogen level of 120 kg N ha-1 at C2 found suitable and economical for cultivation in southern Telangana zone.
Performance of Wheat Genotypes under Late Sown Conditions in Eastern Region of Uttar Pradesh
Authors: Krishna Peram Vamsi , Umesha C. , Satish Reddi , Reddy Satti Maheswara , Raj Gorla Venkata
Published: July 2022

There is an increase in the world population greatly during the past decade. In order to support the growing population scientists are looking towards the high yielding varieties to provide for the world. As such field experiment entitled “Performance of Wheat genotypes under late sown conditions in Eastern region of Uttar Pradesh" was conducted during Rabi  2022  at Wheat Breeding Experimental Field, Department of Agronomy, SHUATS, Prayagraj (U.P). The experiment was laid out in Randomized Block Design with Eight genotypes which were replicated four times. The genotypes used in the experiment are NELS-201, NELS-202, NELS-203, NELS-204, NELS-205, NELS-206, NELS-207, NELS-208. The experiment results revealed that the Wheat genotype NELS-208 performed better than other hybrids viz. Plant height (103.19 cm), dry weight (22.46 g), number of tillers per hill (12.85), number of grains per spike (84.00), spike length (13.40 cm), test weight (40.73 g), grain yield (3.10 t/ha), straw yield (4.85 t/ha), Harvest index (38.99%) was recorded significantly higher compared to other genotypes.
Effect of Phosphorus in Conjoint with Organics and Bioinoculant on Growth, Yield and Quality Parameters of Blackgram in Typic Chromustert
Authors: Suthakar V. , Indirani R. , Kannan P. , Murugan E.
Published: July 2022

Aims: Use of phosphorus fertilizer along with farmyard manure, vermicompost and phosphorus solubilizing bacteria (Bacillus megaterium) in black calcareous soil was conducted to assess the impact on the growth, yield and quality parameters of blackgram variety VBN 8 during the year 2022.

Study Design: Randomized Block Design (RBD) with twelve treatments and three replications.

Place and Duration of Study: Kalligudi block of Madurai district, representing the Southern part of Tamil Nadu during the summer season of 2022.

Methodology: Twelve treatments were followed with various combinations of organics viz, vermicompost and farmyard manure, bioinoculant, and inorganic chemical fertilizer at different ratios. The combinations are 100 per cent and 75 per cent of P2O5 on STCR (Soil Test Crop Response) basis mixed with farmyard manure (1:10 ratio) and vermicompost (1:5 ratio). The impact of different treatments were recorded on shoot length, root volume, SPAD value, Leaf Area Index, grain yield, protein, cystine, and methionine content.

Results: Among the treatments, application of 100% of P2O5 on Soil Test Crop Response (STCR) basis incubated for 30 days with vermicompost at 1:5 ratio + phosphorus solubilizing bacteria @ 2 kg ha-1 T11 has improved the black gram shoot length (27.6 cm), root volume (2.43 cm3), SPAD value (45.91), Leaf Area Index at 20 DAS (1.09) and 40 DAS (3.7), grain yield (936.1 kg ha-1) protein content (23.21%), cystine content (1.97%) and methionine content (2.29%).

Conclusion: The integration of vermicompost and bioinoculant along with phosphorus fertilizer in black calcareous soil has improved the blackgram yield by 35.8% over the use of recommended dose of fertilizer alone. This result highlights the need of integrated application of phosphorus fertilizer along with organics and phosphorus solubilizing bacteria in black calcareous soil for sustainable production of blackgram.
Baseline Susceptibility and Resistance Monitoring of Pyridalyl 10 EC against Plutella xylostella L. (Lepidoptera: Plutellidae) in Tamil Nadu, India
Authors: Logeswaran V. , Krishnamoorthy S. V. , Murugan M. , Karthikeyan S.
Published: July 2022

In vitro studies were conducted to assess the baseline toxicity of pyridalyl 10 EC against Diamondback moth, Plutella xylostella collected from four major cabbage and cauliflower growing tracks in Tamil Nadu. The LC50 and LC95 values of Pyridalyl 10 EC from F1 to F15 generations declined from 2.528 to 0.447 ppm and 14.978 to 2.235 ppm respectively. The susceptibility index to pyridalyl was 5.655 based on LC50 and 6.702 based on LC95. With regard to number of generation required for ten-fold decrease in LC50 was 19.934. Considering the F15 population of P. xylostella as the most susceptible, the tentative discriminating dose arrived was 2.235 ppm. Resistance monitoring studies of P. xylostella across locations viz. Coimbatore, Hosur, Ooty, and Oddanchatram indicated that the per cent resistance ranged from the lowest of 2.008 ppm in Oddanchatram to the highest of 3.696 ppm in Hosur. The Pyridalyl 10 EC reflected the highest resistance ratio of 8.268 fold in Hosur field population and the lowest resistance ratio of 4.492 fold in Oddanchatram field population.
Screening of Big Onion Varieties for Sodicity Tolerance at Cauvery Delta Zone in South India
Authors: Vetrivel M. , Amutha R. , Kalarani M. K. , Paramaguru P. , Rajanbabu V.
Published: July 2022

Sodicity is a major factor affects crop growth and productivity at global level. Out of 1.5 billion ha of cultivable land at global level, 23% are affected due to salinity and 37% by sodicity. Fourteen Big onion varieties were screened by employing germination test in an osmatic solution of Na2CO3 (Sodium bicarbonate).Simultaneously, all the varieties were allowed to germinate in distilled water (control).Three Replications of 20 seeds of each variety were counted and distributed over two layers of paper towel (21x21 cm) previously moistened with water equivalent to three times the dry weight of the paper and tied both ends with rubber band and kept in a plastic tray with different concentrations ( 0, 25mM, 50mM, 75mM, 100 M ) of Na2CO3. At the end of the 21st day, final germination percent, root length, shoot length, root dry weight, shoot weight, Relative water content and membrane stability index, were recorded in Na2CO3 solution as against the distilled water was calculated. The experiment was designed as a completely randomized design with two factors.  As a result a decline in all onion growth paramers, with increasing sodicity stress has been recorded. Significant differences were observed between the varieties and different Na2CO3 concentrations. Irrespective of Na2CO3 concentrations, Bhima Safed recorded significantly maximum stress tolerant index compared to other varieties and minimum stress tolerant index value recorded bhima red variety. Based on stress tolerant index, Bhima safed variety tolerant to sodicity stress and Bhima red variety sensitive to sodicity stress.
Genetic Evaluation of Gerbera (Gerbera jamesonii Bolus ex. Hooker F.) under Naturally Ventilated Polyhouse in Prayagraj
Authors: Donadkar Mrudula Rajendra , Fatmi Urfi
Published: July 2022

An investigation was carried out in nine genotypes for eleven quantitative characters of gerbera to examine genetic variability, heritability, genetic advance, correlation, path coefficient during 2021-2022 in Randomized block design at Research field of Department of Horticulture, Sam Higginbottom University of Agriculture, Technology And Sciences, Prayagraj (U.P), India. The results revealed that the genotype Cut T/C Pink (5.67) was identified best for flower yield per square meter whereas Cut T/C Red and Sisal was having lowest flower yield per meter square. Analysis of variance showed significant difference among nine genotypes, indicating ample scope for selection of promising genotypes. Highest PCV and GCV were recorded for length of stalk (cm) (49.06 and 48.45 respectively) followed by plant height (cm) (47.56 and 46.95 respectively). Lowest PCV and GCV were recorded by vase life (18.67 and 16.26 respectively) followed by diameter of disc (24.185 and 23.487 respectively). High heritability (h2) coupled with high genetic advance were observed for the characters like days to first flower bud initiation (95.31 & 52.73), length of stalk (97.52 & 33.04), plant height (97.45 & 28.79) and plant spread (95.31 & 52.73). Number of leaves and flowers per plant showed significant positive correlation. Plant height, plant spread, number of leaves, days to first flower bud initiation and flower per plant had direct positive effect on flower yield per meter square.
Association between Vessel Density and Visual Acuity in Patients with Diabetic Retinopathy
Authors: Ahmed Walaa Abdelnaeem , El-Emam Sharif Yousef , Mahmoud Mostafa Abdellatif , Serag Yasser Ragab
Published: July 2022

Background: In the non-proliferative stage, diabetic retinopathy (DR) is a retinal vascular disease. Characterised by the formation of micro aneurysms, retinal haemorrhages, exudates, venous alterations, and capillary non-perfusion.  With the usage of optical coherence tomography angiography (OCTA), the purpose of this study was to determine the correlation between vessel density and best corrected visual acuity (BCVA) in DR patients.

Methods: This prospective observational research was done on 50 eyes of 35 consecutive diabetic patients who were diagnosed with mild, moderate or severe non-proliferative diabetic retinopathy (NPDR) and patients with proliferative diabetic changes (as NVD and neovascularization elsewhere (NVE)) as well as a control group consisting of 20 eyes of 10 healthy age-matched participants. Participants were divided into two groups: group A (diabetic patients): sub divided group A1: 40 eyes diagnosed with NPDR and A2: 10 eyes diagnosed with proliferative diabetic retinopathy (PDR) and group B (control group): 20 healthy eyes of age matched participants as a control group. All the eyes were subjected to fund us fluoresce in angiography (FFA) and OCTA. Comparison was made between the vascular density index (VD) in the different slaps between NPDR and PDR group, as well as correlation between the VD and BCVA.

Results: Significant positive correlation was observed between visual acuity (Log MAR) and vascular density index of superficial layer, deep layer in NPDR group and PDR group. Significant positive correlation was observed between vascular density index of superficial, deep layer and best corrected visual acuity (BCVA) (Log MAR) in NPDR group and PDR group.

Conclusions: Using OCTA enhance our awareness of the micro vascular alterations found in DR and allow assessment of disease severity.
Chemical Constituents and Pharmacological Effects of Dolichandrone Species: A Review
Authors: Kumaresan P. Thirupathy , Venkateshan N. , Dhineshmani M. , Junuha M. R. , Uma G. Shifama, , Beevi T. Kateeja , Vaishnavi T. Sri
Published: July 2022

Previously conducted study confirmed that Dolichandrone species showed antimicrobial, anti-oxidant, and antinociceptive properties, as well as anti-cancer, thrush therapy, and fish poisoning effects. This review focuses on the chemical constituents and pharmacological effects of the Dolichandrone genus.
Challenges of Exclusive Breastfeeding among Working Class Women in a Teaching Hospital South East, Nigeria
Authors: Ibekwe Adaobi Maryann , Obeagu Emmanuel Ifeanyi , Ibekwe Chisom Evelyn , Onyekwuo Chinonye , Ibekwe Chioma Vivian , Okoro Amarachukwu Doris , Ifezue Chioma Blessing
Published: July 2022

This research work seeks to investigate the challenges of exclusive breastfeeding among working class mothers in Nnamdi Azikiwe University Teaching Hospital Nnewi Anambra State Nigeria. The objective of the present study is to investigate the attitude of working mothers to exclusive breastfeeding (EBF) in Nnamdi Azikiwe Teaching Hospital, Nnewi North L.G.A., Anambra State, Nigeria. The study unravel those socio-economic determinates of exclusive breastfeeding among working mother's in Nnamdi Azikiwe Teaching Hospital, Nnewi in order to give recommendations that will help improve the rate of exclusive breastfeeding. Descriptive survey design was used in the study. Descriptive survey method was used to observe, describe and document aspects of the attitude of working class mothers towards exclusive breastfeeding. Data from the survey was statistically analyzed using the Statistical Package for Social Sciences (SPSS) (version 12.0). 120 mothers participated in this study; they were selected based on the inclusion criteria and their availability at the time of the survey. Socio-demographic characteristics of mothers were presented in a cross-tabulation.
Electrogenic reaction step and phospholipid translocation pathway of the mammalian P4‐ATPase ATP8A2
Authors: Tadini‐Buoninsegni Francesco , Mikkelsen Stine A. , Mogensen Louise S. , Holm Rikke , Molday Robert S. , Andersen Jens Peter
Published: July 2022

ATP8A2 is a mammalian P4‐ATPase (flippase) that translocates the negatively charged lipid substrate phosphatidylserine from the exoplasmic leaflet to the cytoplasmic leaflet of cellular membranes. Using an electrophysiological method based on solid supported membranes, we investigated the electrogenicity of specific reaction steps of ATP8A2 and explored a potential phospholipid translocation pathway involving residues with positively charged side chains. Changes to the current signals caused by mutations show that the main electrogenic event occurs in connection with the release of the bound phosphatidylserine to the cytoplasmic leaflet and support the hypothesis that the phospholipid interacts with specific lysine and arginine residues near the cytoplasmic border of the lipid bilayer during the translocation and reorientation required for insertion into the cytoplasmic leaflet.
ERCC5, HES6 and RORA are potential diagnostic markers of coronary artery disease
Authors: Bai Zhifeng , Luo Yuanyuan , Tian Linyun
Published: July 2022

The mortality rate of patients with coronary artery disease (CAD) increases year by year, and the age of onset is decreasing, primarily because of the lack of an efficient and convenient diagnostic method for CAD. In the present study, we aimed to detect CAD‐correlated biomarkers and the regulatory pathways involved through weighted co‐expression network analysis. The microarray data originated from 93 CAD patients and 48 controls within the Gene Expression Omnibus (GEO) database. The gene network was implemented by weighted gene co‐expression network analysis, and the genes were observed to fall into a range of modules. We took the intersection of genes in the modules most correlated with CAD with the differentially expressed genes of CAD, which were identified by applying the limma package. Lasso regression and support vector machine recursive feature elimination algorithms were used to determine CAD candidate signature genes. The biomarkers for diagnosing CAD were detected by validating candidate signature gene diagnostic capabilities (receiver operating characteristic curves) based on data sets from GEO. Three modules were selected, and 26 vital genes were identified. Eight of these genes were reported as the optimal candidate features in terms of CAD diagnosis. Through receiver operating characteristic curve analysis, we identified three genes (ERCC5, HES6 and RORA; area under the curve > 0.8) capable of distinguishing CAD from the control, and observed that these genes are correlated with the immune response. In summary, ERCC5, HES6 and RORA may have potential for diagnosis of CAD.
Supramolecular Nitric Oxide Depot for Hypoxic Tumor Vessel Normalization and Radiosensitization
Authors: Yang Cuihong , Mu Ganen , Zhang Ying , Gao Yang , Zhang Wenxue , Liu Jinjian , Zhang Wenwen , Li Paiyun , Yang Lijun , Yang Zhimou , Gao Jie , Liu Jianfeng
Published: July 2022

In cancer radiotherapy, the lack of fixed DNA damage by oxygen in hypoxic microenvironment of solid tumors often leads to severe radioresistance. Nitric oxide (NO) is a potent radiosensitizer that acts in two ways. It can directly react with the radical DNA thus fixing the damage. It also normalizes the abnormal tumor vessels, thereby increasing blood perfusion and oxygen supply. To achieve these functions, the dosage and duration of NO treatment need to be carefully controlled, otherwise it will lead to the exact opposite outcomes. However, a delivery method that fulfills both requirements is still lacking. A NO depot is designed for the control of NO releasing both over quantity and duration for hypoxic tumor vessel normalization and radiosensitization. In B16‐tumor‐bearing mice, the depot can provide low dosage NO continuously and release large amount of NO immediately before irradiation for a short period of time. These two modes of treatment work in synergy to reverse the radioresistance of B16 tumors more efficiently than releasing at single dosage.
Why it is Unfortunate that Linear Machine Learning “Works” so well in Electromechanical Switching of Ferroelectric Thin Films
Authors: Qin Shuyu , Guo Yichen , Kaliyev Alibek T. , Agar Joshua C.
Published: July 2022

Machine learning (ML) is relied on for materials spectroscopy. It is challenging to make ML models fail because statistical correlations can mimic the physics without causality. Here, using a benchmark band‐excitation piezoresponse force microscopy polarization spectroscopy (BEPS) dataset the pitfalls of the so‐called “better”, “faster”, and “less‐biased” ML of electromechanical switching are demonstrated and overcome. Using a toy and real experimental dataset, it is demonstrated how linear nontemporal ML methods result in physically reasonable embedding (eigenvalues) while producing nonsensical eigenvectors and generated spectra, promoting misleading interpretations. A new method of unsupervised multimodal hyperspectral analysis of BEPS is demonstrated using long‐short‐term memory (LSTM) β‐variational autoencoders (β‐VAEs) . By including LSTM neurons, the ordinal nature of ferroelectric switching is considered. To improve the interpretability of the latent space, a variational Kullback–Leibler‐divergency regularization is imposed . Finally, regularization scheduling of β as a disentanglement metric is leveraged to reduce user bias. Combining these experiment‐inspired modifications enables the automated detection of ferroelectric switching mechanisms, including a complex two‐step, three‐state one. Ultimately, this work provides a robust ML method for the rapid discovery of electromechanical switching mechanisms in ferroelectrics and is applicable to other multimodal hyperspectral materials spectroscopies.
Vapor‐Assisted In Situ Recrystallization for Efficient Tin‐Based Perovskite Light‐Emitting Diodes
Authors: Zhang Fang , Min Hao , Zhang Ya , Kuang Zhiyuan , Wang Jiaqi , Feng Ziqian , Wen Kaichuan , Xu Lei , Yang Chao , Shi Haokun , Zhuo Chunxue , Wang Nana , Chang Jin , Huang Wei , Wang Jianpu
Published: July 2022

Tin‐based perovskites are a promising candidates to replace their toxic lead‐based counterparts in optoelectronic applications, such as light‐emitting diodes (LEDs). However, the development of tin perovskite LEDs is slow due to the challenge of obtaining high‐quality tin perovskite films. Here, a vapor‐assisted spin‐coating method is developed to achieve high‐quality tin perovskites and high‐efficiency LEDs. It is revealed that solvent vapor can lead to in situ recrystallization of tin perovskites during the film‐formation process, thus significantly improving the crystalline quality with reduced defects. An antioxidant additive is further introduced to suppress the oxidation of Sn2+ and increase the photoluminescence quantum efficiency up to ≈30%, which is an approximately fourfold enhancement in comparison with that of the control method. As a result, efficient tin perovskite LEDs are achieved with a peak external quantum efficiency of 5.3%, which is among the highest efficiency of lead‐free perovskite LEDs.
Tungsten‐based Nanomaterials in the Biomedical Field: A Bibliometric Analysis of Research Progress and Prospects
Authors: Gu Chenglu , Wang Zhiqiang , Pan Yawen , Zhu Shuang , Gu Zhanjun
Published: July 2022

Tungsten‐based nanomaterials (TNMs) with diverse nanostructures and unique physicochemical properties have been widely applied in the biomedical field. Although various reviews have described the application of TNMs in specific biomedical fields, there are still no comprehensive studies that summarize and analyze research trends of the field as a whole. To identify and further promote the development of biomedical TNMs, a bibliometric analysis method is used to analyze all relevant literature on this topic. First, general bibliometric distributions of the dataset by year, country, institute, referenced source, and research hotspots are recognized. Next, a comprehensive review of the subjectively recognized research hotspots in various biomedical fields, including biological sensing, anticancer treatments, antibacterials, and toxicity evaluation, is provided. Finally, the prospects and challenges of TNMs are discussed to provide a new perspective for further promoting their development in biomedical research.
Tumor budding may be a promising prognostic indicator in intrahepatic cholangiocarcinoma: A multicenter retrospective study
Authors: Kosaka Hisashi , Ishida Mitsuaki , Ueno Masaki , Komeda Koji , Hokutou Daisuke , Iida Hiroya , Hirokawa Fumitoshi , Matsui Kosuke , Sekimoto Mitsugu , Kaibori Masaki
Published: July 2022

Purpose

This retrospective study evaluated our hypothesis that high tumor budding (≥10 buds) may help determine the appropriate T category for more accurate staging of intrahepatic cholangiocarcinoma (ICC).

Methods

We analyzed the clinical and histopathologic data of 235 consecutive patients with histologically confirmed ICC following hepatectomy at five university hospitals in the Kansai region of Japan between January 2009 and December 2020. ICC staging was based on the Liver Cancer Study Group of Japan (LCSGJ) staging system, 6th edition.

Results

Patients with ICC with high budding showed significantly shorter disease‐specific survival (DSS) and disease‐free survival (DFS) than patients with low/intermediate budding. Cox proportional hazards regression analysis showed a hazard ratio of 2.2‐2.3 (P < 0.05) for high budding. Based on these results, we modified the T category of ICC in the LCSGJ staging system by adding severity of tumor budding as a fourth determinant. This proposed staging system for ICC has significantly improved the prognostic accuracy for both DSS and DFS (both: P < 0.05).

Conclusions

High tumor budding is a new candidate for an additional determinant of the T category in staging ICC. An LCSGJ staging system containing an additional evaluation of tumor budding may lead to improved staging accuracy.