bluuebunny/crossref_metadata_2025 huggingface dataset:
احکام القرآن للجصاص میں قواعد فقہیہ اور قواعد اصولیہ کا تحقیقی مطالعہ
Authors: Shah Hafiz Muazzum , Khan Dr Ghulam Hussain , Khan Dr.Haris Saleem
Published: April 2022

Imam Abu Bakar AL Jassas Al Razi is one of the Prominent exegetes and legal theorists who occupy a distinguished place among Hanafi jurists. He was born in 305 AH and remained a famous Hanafi Legal expert in Baghdad. He wrote a commentary on the Qur'an entitled Ahkam al-Qur'an (The Legal Rulings of the Qur'an) with emphasis on the verses having legal importance. This commentary deals with the deduction of juristic injunctions and rulings from the noble Qur’an in a systematic and methodical way. This research is basically a discussion on AL-Jassas's methodology of deduction of rulings from the Holy Quran with special reference to the principles of Islamic Jurisprudence he used in his commentary on the Quran. The research is a focused study of some important Qawaed Usooliyyah he has applied during his discussion on the various rulings he derives from the Quranic Verses.  This study proceeds with an introduction and short biography of Imam Abubakar Al-Jassas followed by an explanation of the general methodology he adopted in His Tafseer. The second part of the study focuses on some important Qawaed Usooliyyah applied and discussed by the AL-Jassas. The last part of this study consists of the conclusion and findings of this article. The study found that Al-Jassas has discussed most of the Qawaed Usooliyyah either explicitly or explicitly and applied them in the process of deduction of rulings from the Holy Quran. He has also used some Qawaed Usooliyyah which he derives from the different verses of the Quran.
Dementia Concerns and Considerations: A CADTH Panel of People With Lived Experience
Authors: Boucher Julie
Published: April 2022

As the number of Canadians living with dementia rises, so does the demand for dementia-related care across the country.

CADTH convened a 5-member panel of individuals with lived experience of dementia to hear about and learn from their firsthand experiences with dementia-related care, treatment, supports, and services.

The panel highlighted the need for care, treatment, supports, and services that prioritize personhood, are inclusive of individuals with young-onset dementia, strike a balance between safety and empowerment, help with navigating the health care system, and involve dignified and respectful communication.

Supporting people transitioning into dementia and their loved ones and ensuring that they receive care that meets their unique needs, abilities, personal preferences, and values will require meaningful involvement of individuals during planning, development, and delivery of treatment, supports, and services.

These insights from the panel will be available for upcoming CADTH reviews of medical procedures, devices, diagnostics, and drugs related to dementia. They will also be used to identify health technologies and potential topics for future CADTH work about dementia.
The THE EFFECT OF HEALTH EDUCATION ON ABILITY LEVELS IN BURN FIRST AID IN AL-LATHIFAH ISLAMIC BOARDING SCHOOL
Authors:   STIKES Kepanjen Malang, Safitry Andres , Jainurakhma Janes ,   STIKES Kepanjen Malang, Muhammad Zulfikar ,   STIKES Kepanjen Malang
Published: April 2022

Burns can occur due to negligence in everyday life or an accident both at home, industry and even due to mass accidents. With so many people still making mistakes or don't know how to do first aid right. The purpose of this study was to determine whether there was an effect of health education using simulation methods with booklet media on the ability of students to provide first aid to burn victims at Al-Lathifah Islamic Boarding School. This type of research uses experimental research designs with one group pretest-posttest design approach. The sampling technique uses purposive sampling with a sample of 35 respondents. The research instrument used observation sheets which were then analyzed by the Wilcoxon test. From the research results, the mean at pre-test is 1.63 and after the post-test is increased, the mean is 13.66. Based on the Wilcoxon test, a significant P-value of <0.001 is obtained, which can be interpreted as influencing before and after health education is given. With the majority of respondents who were teenagers, health education using simulation methods with a media booklet for 60 minutes was able to influence the level of ability in first aid burns. Giving first aid skills to the right burn victims in the Islamic boarding school environment is very much needed, to prevent defects in the integrity of the skin due to burns.
ANALYSIS OF FACTORS AFFECTING PMTCT PROGRAMS IN THE STRATEGY TO REDUCE HIV NUMBERS IN SITUBONDO DISTRICT
Authors:   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia, Reffita Lea Ingne
Published: April 2022

PMTCT is a government program to prevent HIV infection from mothers who are transmitted to their babies. An increasing number of women infected with HIV are getting higher. along with the increase in the number of men who have unprotected sexual relations and through injecting drugs, who will transmit HIV to their sexual partners. The purpose of this study is to explore the implementation of the PMTCT program in Situbondo Regency. The research design used is qualitative research with a phenomenological approach. Data collection uses indepth interview techniques with semi-structured questions. The sampling technique in this study used purposive sampling with a sample of 8 informants from 17 existing informants. The results of the study show that the process of implementing the PMTCT program influences the development of the PMTCT program each year and will have a positive impact both for health workers and for women who are pregnant. In the process of implementing the PMTCT program, it is influenced by several factors, among others there are factors that support the process of implementing the PMTCT program as well as those that inhibit. Of these inhibiting factors, a number of special efforts and strategies were undertaken to support the implementation of the PMTCT program. In the process of implementing the PMTCT program there are some hopes to support the course of the PMTCT program, namely the existence of a poly VCT to improve this service in the future. Based on this research further research is needed on the process of implementing the PMTCT program
THE EFFECT OF PLAYDOUGH THERAPY ON THE IMPROVEMENT OF FINE MOTORCYCLE IN PRE SCHOOL CHILDREN
Authors:   Universitas Muhammadiyah Bengkulu, Indonesia, Ferasinta Ferasinta , Novtari Ewi ,   Universitas Muhammadiyah Bengkulu, Indonesia, Dinata Endah Zulya ,   RSU UMMI Bengkulu, Indonesia
Published: April 2022

Preschool children are children aged between 3-6 years, while at 4-6 years they usually attend kindergarten programs. It is hoped that they have been able to master several skills that require fine motor skills, such as using playdough by cutting in accordance with the fine motor development that must be achieved.This study aimed to determine the effect of playing therapy by using playdough with patterns cutting toward improving fine motor skills in preschool children in the Kedurang Health Center Work Area. This research design used a quasi experiment. A sample of 15 preschool children was taken by purposive sampling. The results of test analysis in the pre and post therapy intervention group playing playdough obtained a p-value of 0.000. There is a significant effect after playing playdough therapy on improving fine motor skills in preschool children. It is expected that the PAUD Nurul Amal Kab. South Bengkulu, the working area of ​​the Kedurang Public Health Center, can be more creative in using learning methods such as playdough so that children's fine motor skills are more stimulated.
STUNTING DI DESA PLABUHAN KECAMATAN PLANDAAN KABUPATEN JOMBANG
Authors:   Universitas Darul Ulum, Wahyuningsih Endah , Mukar Mukari i ,   Universitas Darul Ulum, Susetiani Arin Eka ,   Universitas Darul Ulum
Published: April 2022

Stunting is a condition in which toddlers experience failure in their growth and development due to insufficient nutrition. The research was conducted to abtain a complete potrait/ picture of stunting in village of Plabuhan.This research method is qualitative with informants consisting of mothers who have children under five with stunting, rural government, rural midwives and posyandu cadres. Data obtained from interviews and stunting data in the village. Data analysis with reduction, presentation, drawing conclusions.The result shows that stunting in the village of Plabuhan is caused by multiple factors ranging from economic factors, knowledge and also cultural factors.In a socio-cultural perspective, the condition of stunting that occurs is not considered as a sick condition so it requires special attention, the condition of stunting is understood as a condition that is accepted because of reasonableness where some of them have ancestors who are also short / small.
THE EFFECT OF BROKEN WATER LEAVES ON THE REDUCTION OF URIC ACID LEVELS IN URIC ACID SUFFERERS IN WONOSARI VILLAGE, SENORI DISTRICT, TUBAN DISTRICT
Authors:   STIKes Husada Jombang, Jawa Timur, Indonesia, Kurniawan Vendi Eko
Published: April 2022

Uric acid is the result of purine metabolism in the body contained in the blood and urine. There are several ways to overcome uric acid, one of therapy herbal bay leaf. The purpose of this study to the influence of the water decoction of the leaves to decrease the levels of uric acid in patients with gout in the Village of Wonosari Kecamatan Senori Tuban Regency. The design used in this research is pre-experimental approach with one-group pretest-posttest design. This research was conducted in the Village of Wonosari Kecamatan Senori Tuban on December 15-23 May 2020. Population and sample in this study were all patients with gout in the Village of Wonosari Kecamatan Senori Tuban Regency a number of 37 people by using a sampling technique total sampling. While the instrument used is a tool checks the uric acid and checklist. Data analysis by using T-Test. The results of this research note that the average uric acid levels before the administration of water decoction of bay leaf is 7,549 mg/dl. While the average levels of uric acid after administration of water decoction of bay leaf is 5,616 mg/dl. Data analysis using T-Test obtained ρ = 0.000 < α = 0.05 so H1 is accepted meaning that there is the effect of water decoction of the leaves to decrease the levels of uric acid in patients with gout. Efforts of health workers so that uric acid levels decreased is to provide IEC about the use of water decoction of bay leaf as a treatment alternative in patients with gout.
THE RELATIONSHIP OF DISEASE STADIUM AND SPIRITUAL WELL-BEING OF BREAST CANCER PATIENTS
Authors:   STIKes Estu Utomo Boyolali, Indonesia, Afifah Vina Asna , Sari Ilma Widiya ,   STIKes Estu Utomo Boyolali, Indonesia, Nofiah Niafatun ,   Akademi Keperawatan Bahrul Ulum Jombang
Published: April 2022

Spiritual well-being is an important thing that needs to be considered for breast cancer patients. Low spiritual well-being can make patients hopeless and feel insignificant, especially when the disease stage begins to develop into an advanced stage. The purpose of the study to know the relationship disease stage and spiritual well-being of breast cancer patients. The design of research used a cross sectional approach. The sampling technique used purposive sampling as many as 32 respondents. The results showed that 24 respondents (75%) were in stage 3 and spiritual well-being in the moderate category was 22 respondents (68.8%). Spearman rho correlation test showed a significant relationship between disease stage and spiritual well-being of breast cancer patients (p value 0.028 < 0.05) with a correlation coefficient of -0.389. The conclusion that there was a relationship between the stage of the disease and the spiritual well-being of breast cancer patients with a sufficient correlation value and has a negative correlation meaning that the lower stage of the disease, so the spiritual well-being of breast cancer patients will be better. Results of this study, respondents were hoped that could maintained their health and complied the therapy program so that the stage of the disease does not get worse, besides that respondents were expected to be able to get closer to God Almighty so that spiritual well-being will be better.
LITERATURE REVIEW: THE EFFECT OF BRAIN STORMING ON IMPROVING STUDENT’S SHORT-TERM MEMORY
Authors:   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia, safaatin siti , Wijaya Arif ,   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia, Roni Faishol ,   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia
Published: April 2022

Brain storming is the series of phsycal exercise which has an objective to stimulate or give a prickling the brain potensial. Brain storming exercise will extremely goad the body’s part movement, movement synchronize, learning process, and the daily adjustment for the kid. Brain storming is strongly sugest for the childerns that have less reading comprehension. By doing brain storming, the closure brain part to be open totally. of this literature review is restate the effect of brain storming to the student’s short-term memory. This literature review is held based on the issue, methodology, similarities and the intermediate research purposal. There are five research that using descriptive quantitative method. The population is total of the students, and the sample is the several student at the school. There is an effect in brain storming to the short term memory raising. This study give the alternative way to the parent and the teacher in giving the learning process stimulation and also fulfil the student’s needs, whether at home or at school. For the reviewer, hopfully can develope the movement as the variety of the brain sorming well, in collage student level, senility level, etc.
THE EFFECT OF ALOE VERA AND HONEY ON THE HEALING OF DIABETIC WOUNDS IN DIABETES MELLITUS PATIENTS
Authors:   STIKes Ganesha Husada Kediri, Jawa Timur, Indonesia, Puspitosari Dewi Retno , Nuridayanti Anik ,   STIKes Ganesha Husada Kediri, Jawa Timur, Indonesia, Wahdi Achmad ,   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia, Putri Jayanti Eka Ama ,   STIKes Ganesha Husada Kediri, Jawa Timur, Indonesia
Published: April 2022

Diabetes mellitus is a chronic disease caused by the pancreas not being able to produce insulin, resulting in an increase in blood sugar levels. One of the complications is diabetic foot ulcers. Wound treatment using aloe vera and honey can help heal diabetic wounds. The purpose of this study was to determine the effect of wound care using aloe vera and honey on diabetic wound healing in patients with diabetes mellitus at the Griya Husada Clinic, Kediri City. The research design used Pre-Experiment with One Group Pre-Postest Design. The study population was all patients with diabetes mellitus as many as 20 respondents who were taken by total sampling technique. The results of the study obtained degenerated wounds which eventually regenerated 2 respondents (10%), regenerating wounds that had healed tissue 5 respondents (25%). Analysis of the data with Wilcoxon found differences before and before wound care (p = 0.008 <0.05), then Ho was rejected and Ha was accepted. Therefore, there is an effect of wound care using aloe vera and honey on diabetic wound healing in patients with diabetes mellitus at the Griya Husada Clinic, Kediri City. It is suggested that aloe vera and honey can be applied in wound care to speed up the healing process in diabetic wounds.
NURSING CARE FOR CLIENTS OF DENGUE HEMORRHAGIC FEVER (STUDY OF LITERATURE)
Authors:   Fakultas Ilmu Kesehatan Unipdu Jombang, Indonesia, Aji Pratama Apriawan , Muniroh Siti ,   Fakultas Ilmu Kesehatan Unipdu Jombang, Indonesia, Zuliani Zuliani ,   Fakultas Ilmu Kesehatan Unipdu Jombang, Indonesia
Published: April 2022

Dengue Hemorrhagic Fever (DHF) is an acute infection caused by orbovirus (Arthopodbron virus) and is transmitted through Aedes mosquito bites (Aedes albopictus dan Aedes aegypti). Until now, 4 types of dengue virus were introduced that can cause dengue fever and dengue fever. Regarding the occurrence of dengue fever can be stated as follows. After the dengue virus enters the human body through the bite of the Aedes mosquito the patient's body forms immunity to the disease if the patient is attacked for the second or more times the type of virus is different, it will cause an immunological reaction in the body (Ngastiyah, 2015). The methodology in writing scientific papers uses a literature study with four clients in the scientific papers of the D3 Nursing study program at the Faculty of Health, Unipdu, Jombang in 2014-2018 with the same title, namely nursing care for clients of dengue fever. The results of the implementation of nursing care in four clients with dengue hemoragic fever (DHF), obtained all four clients experience the disease (DHF) with a diagnosis of hyperthermia. Nursing actions made can be carried out well because of the support of all health workers, clients and families and hospital infrastructure but cannot be carried out in a row.
THE RELATIONSHIP BETWEEN FAMILY SUPPORT AND SUCCESSFUL TREATMENT OF PULMONARY TB AT THE PULMONARY POLYCLINIC OF RSUD JOMBANG
Authors:   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia, Happi M , Putri Santoso Shelfi Dwi Retnani ,   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia, Wijaya Arif ,   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia, Prasetyo Joko ,   STIKes Bahrul Ulum Jombang, Jawa Timur, Indonesia
Published: April 2022

Introdaction: Pulmonary TB is an infectious disease caused by the bacillus Mycobacterium tuberculosis. Transmission is through the air and the source of transmission is TB patients whose sputum contains TB germs. The success of treatment is the result (output) of treatment carried out by TB patients, consisting of complete recovery and treatment marked by a negative sputum examination result at the end of treatment. Family support is the attitude, action, and acceptance of sick sufferers. Objective: to determine the relationship between family support and the success of pulmonary TB treatment at the Jombang Hospital polyclinic. Design: using an analytical design using a cross-sectional approach. The number of respondents 30 using purposive sampling, purposive method and in accordance with the inclusion criteria. The measuring instrument used is a questionnaire that has been tested for validity and reliability. The analysis used is the univariate analysis of the frequency distribution and the bivariate Chi¬_Square test.Results: The results showed that 21 people declared good family support and recovered but the results of the Chi_Square test were H0 accepted which means that there is no relationship between family support and the success of pulmonary TB treatment with p-value = 0.021 (< 0.05). Conclusion: it is hoped that the family can provide support to patients with pulmonary TB for the success of their treatment.
THE EFFECTIVENESS OF GINGER BOILED WATER ON THE INTENSITY OF MENSTRUAL PAIN IN FEMALE STUDENTS AT TRIATMA MULYA UNIVERSITY
Authors:   Universitas Triatma Mulya, Hutabarat Naomi Christina , Sri Kesumawati Ketut Anom ,   Universitas Triatma Mulya
Published: April 2022

Menstrual pain is pain that is felt in the lower abdomen when menstruating without any abnormalities in the reproductive organs, it can occur before or during menstruation. Pain during menstruation can be reduced, one way is the management of non-pharmacological therapy by giving herbal drinks in the form of ginger boiled water. Ginger contains essential oils in which there is a chemical content of gingerol which has a strong effect on inhibiting prostaglandin biosynthesis where excessive prostaglandin formation can cause excessive uterine contractions so that it can also increase pain. The purpose of this study was to determine the effect of giving ginger boiled water on the intensity of menstrual pain in students at Triatma Mulya University, Jembrana. Research Methods: The type of research used is a variation of the study in the form of a quasi-experimental plus the concept of one-group pretest-posttest. A total of 135 students of Triatma Mulya Jembrana University were the population in this study. Samples were taken by doing purposive sampling then obtained specimens of twenty (20) female students. description of the information formulated with paired t-test. When water has not been given from boiling ginger, the intensity of menstrual pain shows a range between five to eight which has an average result of seven then after giving water from boiling ginger on the 2nd day shows a range between one to four which has an average of 2.55. the conclusion of the t-test experiment shows that the number at t as much as 24.106 in df 19 has a relevant level of (p) 0.000. Ginger boiled water has the potential to relieve menstrual pain. Triatma Mulya University students who experience pain during menstruation, can use ginger boiled water as an alternative treatment for menstrual pain. Future researchers can conduct further research on the benefits of ginger on menstrual pain by simplifying the serving or by turning ginger into a product
Soft Computing implementation in Tourism Sector: A review
Authors: AL MAZRUII SARA ALI , IBRAHIM BASIL ISMAIL , Hassan Sara Wisam
Published: April 2022

The Corona virus epidemic has had numerous detrimental repercussions on the tourism industry. Domestic production and trade have been impeded by the global epidemic and the mitigation efforts implemented when the disease broke out, according to the World Health Organization in particular. The current study looks at how neural networks and soft computing techniques can help provide accurate and effective predictions for the tourism industry, preventing future losses. The study will compare a number of strategies and procedures in order to determine the most successful technology in the tourism industry.
Ser educadora
Authors: Hoyuelos Alfredo , Silva Marcelo Oliveira da , Oliveira Ana Luisa Dias
Published: April 2022

Não se aplica.
Experiencias del personal de salud sobre la implementación de prácticas de protección contra COVID-19 en Argentina
Authors: Danesi Emmaría , Maltz Tatiana Yael , Blanco Josefina , Peyran Pamela , Carbajal de la Fuente Ana Laura , Fernández Marisa Liliana
Published: April 2022

El objetivo de este estudio fue indagar sobre experiencias y percepciones del personal de salud (PDS) de Argentina en la implementación de protocolos para su protección durante la pandemia por COVID-19. Se realizó una encuesta al PDS a nivel nacional, relevando datos sociodemográficos, de protocolos, recursos y aspectos psicosociales. Se analizaron 2010 encuestas. El 76.4% fueron mujeres, 43 años de edad media, 35% médicos/as y 72.7% del subsistema público. El 37.2% aumentó su carga horaria y el 22.5% presentaba algún factor de riesgo, de quienes 20.4% tuvo licencia o reasignación de tareas. Se establecieron protocolos sobre uso de equipos de protección personal (EPP) en 91% de instituciones y otras temáticas en menor medida. La claridad de los mismos fue bien valorada y hubo entrenamiento en 60.8% de los casos. La conformidad con la disponibilidad y calidad del EPP fue variable, con mejor valoración en el subsector privado. El 60.4% tuvo necesidad de obtener EPP por medios propios. El 48.4%  de los encuestados siguió los protocolos de uso de EPP, variando según grupos de riesgo. El indicador global de valoración institucional fue 6.45/10 (IC 95% 6.38-6.53). El 87.2% del PDS dijo haber sentido angustia y esto se relacionó con peor comunicación con superiores y peor valoración institucional. De este estudio surgen dificultades en la implementación de los nuevos cuidados, y la necesidad de intensificar esfuerzos en recursos y organización institucional para mejorar las condiciones de trabajo.
Muchas gracias
Authors: Revista ASEI
Published: April 2022

El equipo editorial de Actualizaciones en SIDA e Infectología agradece enormemente a los 37 revisores que han dedicado su tiempo y experiencia al cuidadoso proceso editorial de la revista durante los últimos doce meses. En ese lapso se recibieron y evaluaron 25 trabajos, de los cuales 15 fueron aprobados, 5 rechazados y 5 continuaban en proceso de evaluación al finalizar el año 2021.

Los editores desean expresar su sincero agradecimiento a los siguientes revisores por su generosa contribución en la evaluación de trabajos durante 2021.

 

Afeltra, Javier

Arrigo, Diego

Atorri, Silvia

Balasini, Carina

Benetucci, Jorge

Cahn, Florencia

Cecchini, Diego

Contarelli, Jorge

Córdova, Ezequiel

Cunto, Eleonora

de Vedia, Lautaro

Dignani, Cecilia

Fariña, Javier

Freuler, Cristina

Fridman, Vanesa

Gonzalez, Liliana

Guzzi, Leda

Larrosa, Luciana

Lauffer, Natalia

Levalle, Jorge

Lloveras, Susana

Lopardo, Gustavo

Lucas, Mar

Martini, Sergio

Mauas, Romina

Moyano, Mónica

Nemirovsky, Corina

Mykietiuk, Analía

Quirós, Rodolfo

Rollet, Raquel

Spadaccini, Luciana

Rüttiman, Ricardo

Stryjewaki, Martín

Sued, Omar

Teijero, Ricardo
The phytochemical analysis of some Lycium barbarum cultivars obtained by tissue culture
Authors:   ", Glijin Aliona ,   Alexandru Ciubotaru",   National Botanical Garden (Institute), Republic of Moldova
Published: April 2022

The purpose of this paper included the quantitative determination of biochemical compounds (ascorbic acid, reducing sugars, tannins and titratable acidity) in the fruits of three Lycium barbarum L. cultivars ('Licurici', 'New big' and 'Amber Sweet'), propagated by tissue culture and cultivated under the ecological conditions in the Republic of Moldova. The quantifi cation of ascorbic acid resulted in close amounts (7.11 mg/100 g and 7.81 mg/100 g) in the fruits of the 'Licurici' and 'New big' cultivars and signifi cantly lower amounts (3.11 mg/100 g) in the fruits of the 'Amber Sweet' cultivar. Besides, 'Amber Sweet' goji berries contained the lowest amount of reducing sugars. The titratable acidity was between 0.29 and 0.38%, and the maximum content was found in the fruits of the 'Licurici' cultivar. The quantitative assessment of tannins indicated an almost twice lower content in the fruits of the 'Amber Sweet' cultivar, which are yellow, as compared with the other two cultivars, which have red-orange ('Licurici') and intense red fruits ('New big'). The generalization of the obtained results has revealed that the three Lycium barbarum L. cultivars ('Licurici', 'New big' and 'Amber Sweet'), multiplied by micropropagation in the Laboratory of Embryology and Biotechnology of NBGI and cultivated in the Republic of Moldova, are an excellent source of biologically active compounds and can be used for commercial production as a promising super fruit and organic superfood. At the same time, we would like to mention that the climate of the Republic of Moldova is suitable for the cultivation of wolfberry plants, which are highly appreciated for the health benefi ts of their fruits.
Evaluation of the “Pogoreloe” natural protected area after a decade
Authors:   ", Postolache Gheorghe ,   Alexandru Ciubotaru",   National Botanical Garden (Institute), Republic of Moldova, Titica Ghenadie ,   "Alexandru Ciubotaru" National Botanical Garden (Institute), Republic of Moldova
Published: April 2022

As a result of the evaluation of the protected natural area „Pogoreloe” after a decade there have been major changes. It was established that the installation of the reservatogenic protection regime and the development of the project had major changes in the composition and structure of the seedling and grass cover. This situation has both positive and negative consequences. The positive thing is that the regeneration of pedunculate oak has started. A lot of pedunculate oak seedlings have appeared in the protected area, which gives the possibility to grow a new generation of oaks that in the future could replace the secular oaks that are old. For this, it is recommended to carry out the works of eliminating the elm and maple seedling, which in many areas shades the pedunculate oak seedling. As a result of the appearance of this brood, the protected natural area „Pogoreloe” was transformed from a penetrable to impenetrable state. Based on the situation created, it is recommended to remove the elm and maole seedlings where the pedunculate oak seedling is shaded. It is necessary to thin the thickets of elm and maple, so that the young of these species become less in number in order to have a penetrable state of the protected natural area „Pogoreloe”.
Crataego monogynae-Cerasetum mahaleb Pînzaru (Berberidion vulgaris br.-bl. ex tx. 1952) – new association in the vegetation of rocky regions of the Republic of Moldova
Authors:   ", Pinzaru Pavel ,   Alexandru Ciubotaru",   National Botanical Garden (Institute), Republic of Moldova
Published: April 2022

The article describes a new association of scrub vegetation found on the limestone hills in the Republic of Moldova. This association is new for science and includes secondary, xerophilous-xeromesophilous, calciphilous phytocoenoses, formed as a result of the steppe vegetation being replaced by shrubs. The new association – Crataego monogynae-Cerasetum mahaleb Pînzaru has been grouped in the alliance Berberidion vulgaris Br.-Bl. ex Tx. 1952, order Prunetalia spinosae Tx. 1952, class RHMANO-PRUNETEA Rivas Goday et Borja Carbonell. ex. Tx. 1962.
The species of genus Xanthium L. (Asteraceae) in the flora of Republic of Moldova
Authors:   ", Tofan-Dorofeev Elena ,   Alexandru Ciubotaru",   National Botanical Garden (Institute), Republic of Moldova
Published: April 2022

The article contains results of the floristic research on the genus Xanthium L. in the fl ora of Republic of Moldova. As a result of the study, in this territory, 4 species were identified: X. strumarium L., X. albinum (Widd.) H. Scholz & Sukopp, X. orientale L. and X. spinosum L. The dichotomic key for species determination, the synonymy, habitat and biological characteristics of the highlighted species are given.
Ecological assessment of the pastures from the extravilan of the locality of Cimișlia
Authors:   State Agrarian University of Moldova, Melnic Rodica , Mocanu Emilian ,   State Agrarian University of Moldova
Published: April 2022

The productivity of the pastures is influenced by the ecological conditions - climate, relief, geological composition, hydrographic network, soil cover. According to the research, they highlighted some legitimacy of the level of pasture productivity depending on the relief elements – exposure, slope, altitude and shape of the slopes, heat and humidity insurance. In the conditions of the northeastern slope, the production of meadows was higher compared to that obtained on the southwestern slope. In all variants, the production of meadows decreases from the upper to the middle of the slopes and considerably increases to the lower slopes. Meadow productivity decreased from cambic chernozem (4517 kg / ha) to common chernozem (3718 kg / ha) and carbonate chernozem (1677 kg / ha). On marshy alluvial soils the production of meadows is high, but of a lower quality.
ASSOCIATION BETWEEN HASHIMOTO’S THYROIDITIS AND DEPRESSION
Authors: GIGILASHVILI MARIAM , MATITASHVILI GURAM , RAMISHVILI RATI
Published: April 2022

Hashimoto’s thyroiditis is a disease of the thyroid gland which affects the body in various ways leading to somatic complications. In addition to that, it affects the patient’s mental health. The extent of psychiatric diseases in patients with Hashimoto’s thyroiditis is not extensively explored. The primary objective of this study was to find the association between Hashimoto’s disease and depression in female patients aged 36-50 from North America/Central America. Questionnaires were designed to assess the extent of possible depression in those patients. We compared 115 cases to 188 controls. After analyzing results, we found that relative risk for developing depression in patients with hashimoto’s disease was 1.7202 (95% CI 1.4722- 2.0099, p value< 0.001). Thus, we concluded that Hashimoto’s disease is associated with increased risk of development of depression in a given sample.
PAPILLARY THYROID CARCINOMA CONCOMITANT WITH THYROTOXICOSIS
Authors: KALMAKHELIDZE DAVIT , ZAALISHVILI ZURAB , ACHUTHAPRASAD ASHWIN , DARTSIMELIA TEKLE , KALMAKHELIDZE LEVAN
Published: April 2022

Contrary to the preconceived belief, the occurrence of hyperthyroidism in patients with thyroid cancer is gaining in incidence. The research team retrospectively analysed studies such as serum TSH and T4 levels, thyroid ultrasound results, and the histopathology reports of 9 patients (age range 20-67) from Mardaleishvili Medical Center. All patients were diagnosed with PTC. 7 patients had microcarcinoma (mean 6.1mm) and 2 – large tumors (mean 14mm). Graves’ disease was found in 5 patients, toxic nodular goiter in 3 and one patient’s record was lacking comorbid disease information. One patient had confirmed lymph node involvement. All patients underwent total thyroidectomy. Overall, all 9 patients with hyperthyroidism were subsequently diagnosed with thyroid cancer. Management of such patients has questioned the validity of the guidelines published by the ATA and emphasizes the fact that malignancy should not be excluded in patients with thyrotoxicosis.
RESISTANT HYPERTENSION IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA
Authors: AALIF ZAHEER , NARENDRANATH RAVI , MUNEER MOHAMMED BILAL , SAFAR BASHEER
Published: April 2022

Obstructive sleep apnea (OSA) is a sleep disorder characterised as complete or partial upper airflow cessation during sleep. Although it has been widely accepted that OSA is a risk factor for the development of hypertension, the studies focusing on this topic revealed inconsistent results. We aimed to clarify the association between OSA and resistant hypertension among the population of Calicut district in the state of Kerala. The study was conducted using the STOPBANG questionnaire. All individuals included were between the ages of 35-65 and had previously documented resistant hypertension. The responses from 49 people that fit the inclusion criteria have been analysed. 16/49 of the participants were placed in scores of 0-2, 15/49 were placed in scores of 3-4 and 18/49 were placed in the scores of 5-8. Based on our study, we can conclude that OSA is related to an increased risk of resistant hypertension among the population studied.
TAU IMMUNOTHERAPY FOR ALZHEIMER’S (Review Article)
Authors: CHANDRAKUMARAN ABIVARMA , ACHUTHAPRASAD ASHWIN , DANIEL PAK , JACOB JOEL
Published: April 2022

Alzheimer's is a tormenting disease that progressively destroys a person's cognition. Researchers have toiled long and hard to find a cure or slow the course of this disease. Therapies have mainly targeted the two hallmarks of Alzheimer's pathophysiology: amyloid and tau protein. This paper sheds light on the new developments in the field of immunotherapy aimed against tau protein, particularly in comparison to the thus far futile efforts of targeting amyloid. Tau targeting immunotherapy is emerging as a promising therapeutic option.
DIETARY IMPACT ON THE GUT MICROBIOME AND ITS EFFECTS ON CLOSTRIDIUM DIFFICILE, INFLAMMATORY BOWEL DISEASES, AND METABOLIC SYNDROMES (Review Article)
Authors: SHAJI ABIN , RUKSAR SALIM SALMA , MANISHA TAMILMARAN , MOHANADAS RUPESH
Published: April 2022

Gut microbiomes have long been known to have diverse effects on normal human health. Medical researchers and microbiologists have studied how it is maintained, about its composition, and how it can be altered. Different types of diets have varied implications on the gut microbiota and its homeostasis. This review paper discusses the different studies conducted on the matters of how diets influence the gut microbiome and also its effect on certain medical conditions, Clostridium difficile infection, Inflammatory bowel disease, and metabolic syndrome.
SELECTED NEUROLOGIC AND PSYCHIATRIC OUTCOMES IN PATIENTS TREATED WITH CLOZAPIN (Review Article)
Authors: TSENTERADZE TAMAR , KOCHIASHVILI GIORGI , GABADADZE MARIAM , KALMAKHELIDZE DAVIT , ZAALISHVILI ZURAB
Published: April 2022

Clozapine is a second-generation antipsychotic mostly used for treatment-resistant schizophrenia and acute suicidality. Although clozapine’s efficacy is well-documented, it has various side effects which need to be promptly addressed. In this article, we focus on neurological and psychiatric side effects. Among these side effects, seizure is a well-known complication of clozapine therapy. The articles that we reviewed concerning seizures and EEG changes in association with clozapine plasma levels and doses, found significant relations in some but not all cases. In addition to seizures, extrapyramidal side effects are common adverse effects of clozapine which can be an acute or chronic condition. Clozapine is also associated with ocular disturbances such as retinal pigmentation. It has also been shown to cause cataplexy. Moreover, clozapine can cause significant sedation. Effects of clozapine on sleep is still a controversial subject. The studies demonstrate inconsistent results. Cholinergic rebound syndrome is a rare complication of longterm clozapine use, which itself can be the inducer of insomnia. Apart from this, hypersalivation is one of the most frequent side effects with a paradoxical pathophysiology. Finally, clozapine is associated with severe psychiatric side effects, some of which need prompt intervention.
Redefining the Boundaries of Public Sector Accounting Research?
Authors: Lambert Vicky , Lapsley Irvine
Published: April 2022

In this paper we assess the different contributions to public sector accounting research in recent decades. We draw on Burrell and Morgan’s (1985) framework to study two distinct aspects of public sector accounting: first, the Private Finance Initiative/public-Private Partnerships (PFI/PPP); and second, budgets in public sector institutions. While PFI/PPP is a recent phenomenon, budgeting in the public sector is often regarded as the fundamental element of financial managemeni in public services. This paper explores whether there are differences in motivation in research in these different aspects of public sector accounting.
Private or Public Debt? Drivers of Debt Priority Structure for UK Firms
Authors: Barnes Edel , Cahill Brian
Published: April 2022

Literature on corporate financing structure has focused on the debt/equity decision with less attention devoted to debt issuance, particularly for UK firms. We examine debt ownership structure for UK FTSE 350 firms at 2001 year end, emphasising the relationship between debt structure and firm characteristics. Our decision choice model relates a variety of attributes to the probability that firms will choose to issue debt publicly rather than to the public debt ratio per se. Our results highlight the importance of firm size, credit quality and prior leverage in debt issuance decisions but offer little support for information asymmetry, adverse selection or reputational considerations. However, riskier firms appear to use more debt, contrary to our priors.
Non-autonomous dynamical systems and their applications
Authors:   Moldova State University, Cheban David
Published: April 2022

This article is devoted to a brief overview of the author’s works over the past 10-15 years on non-autonomous dynamic systems and their applications. Non-autonomous dynamical systems are a new and rapidly developing field of mathematics (theory of dynamical systems). Thousands of articles, dozens of reviews and a number of monographs on non-autonomous dynamic systems and their applications have been published over the past 10-15 years. Special international conferences and scientific journals are dedicated to them. My results on non-autonomous dynamical systems and their applications are published in three monographs. In this article, we provide an overview of these results.
Temperature Induced Spin Transition in Co(II) Complex
Authors:   Institutul de Fizică Aplicată, Republica Moldova, Ostrovsky Serghei , Klokishner Sophia ,   Institutul de Fizică Aplicată, Republica Moldova
Published: April 2022

A microscopic theoretical approach for the description of spin transitions in mononuclear Co(II) compounds is suggested. Two types of interionic interactions are taken into account, namely, the electron-deformational interaction and the cooperative Jahn-Teller interaction arising from the coupling of the low-spin state of the Co(II) ion with the tetragonal vibrations of the nearest surrounding. The different role of these interactions in the spin transformation is demonstrated and discussed. A qualitative and quantitative explanation of the experimental data on the temperature dependence of the magnetic susceptibility for the [Co(pyterpy)2](PF6)2 compound is given
Fundamental contributions to the creation of the database of the natural protected areas cadastre of Moldova
Authors:   Institutul de Ecologie și Geografie, Republica Moldova, Tarita Anatolie
Published: April 2022

The Institute of Ecology and Geography, responsible for the creation and maintenance of the Natural Protected State Areas (NPSA) Cadastre database included in the NPSA Fund, between years 2015–2021), conducted complex scientific research, generalized and made the ecological passports of 312 objects and complexes from the NPSA Fund, which resides in the accumulation of data on their current state, valuable elements, the quality of the environmental components in their territory, with a view to the conservation of biological diversity and the sustainable exploitation of natural resources. It has been established that the majority of NPSA corresponds to the category of protected area (scientific reserve, natural monument, natural reservation etc.) and in general the protection regime is respected. The ecological status of the environmental components is better in NPSA located in the forest fund; in other categories of areas the ecological status is satisfactory. For the extension of the NPSA Fund, 10 new representative areas with a special natural and ecological potential, with a total area of approx. 1 400 ha, were proposed to the Ministry of Environment, to the Environment Agency for their evaluation in order to include them in the Annexes of Law no. 1538/98.
Management of sunflower crop in Moldovan agricultural households
Authors:   Universitatea de Stat din Moldova, Duca Maria , Clapco Steliana ,   Universitatea de Stat din Moldova, Burcovschi Ion ,   Universitatea de Stat din Moldova
Published: April 2022

In the Republic of Moldova, the oilseed crop sunflower (Helianthus annuus L.) occupies consistent cultivation areas (about 25 % of arable land), which is constantly growing. Trends in agricultural systems from recent decades (intensification and specialization of production), associated with intensive use of agrochemicals (pesticides and fertilizers), irrational land use, non-compliance with crop rotations etc. have led to declining soil quality, biodiversity loss, a significant increase in the incidence of diseases and pests and the vulnerability of agricultural ecosystems to climate change. In order to address the principles of sustainable and ecological agriculture, it is interesting to know in depth the current situation of biotechnologies for sunflower cultivation and the incidence and severity of pathogen attack. This paper reflects the results of analyzes conducted based on farmers’ opinion survey, focused mainly on parameters such as areas cultivated with sunflower, types of cultivated hybrids, geographical distribution of sunflower-specific pathogens, applied agricultural practices etc.
Application of the WQI method in the study of the quality of groundwater in the district of Causeni
Authors:   Institutul de Chimie, Republica Moldova, Mitina Tatiana , Bondarenco Nadejda ,   Institutul de Chimie, Republica Moldova, Grigoras Diana ,   Institutul de Chimie, Republica Moldova, Lupascu Tudor ,   Institutul de Chimie, Republica Moldova
Published: April 2022

There has been investigated the chemical composition of groundwater from a series of wells from Causeni district, Republic of Moldova. Using the Water Quality Index (WQI), the quality of the analyzed water has been classified. It was emphasized that the water from artesian wells does not meet the state standards for the drinking water. The quality indexes – the content of ammonia and ammonium ions, hydrogen sulfide and soluble sulfides, as well as the content of sodium and fluorine ions. exceed the maximum permissible concentrations (MPC), while the total hardness is under the MPC parameters. In groundwaters, the exceeding of the maximum permitted concentrations for the content of nitrates, nitrites, ammonium ions, calcium and magnesium salts, sodium ions, sulphates, etc. was registered most frequently. Using the WQI method, it was shown that none of the analyzed water samples from artesian wells were classified as “excellent” or “good”. Only two water samples from wells entered the ”good” category
Stimulating bee feed with natural polydisperse chitosan
Authors:   Universitatea Agrară de Stat din Moldova, Eremia Nicolae , Cataraga Ivan ,   Universitatea Agrară de Stat din Moldova, Coseleva Olga ,   Universitatea Agrară de Stat din Moldova, Pogrebnoi Serghei ,   Institutul de Chimie, Republica Moldova, Macaev Fliur ,   Institutul de Chimie, Republica Moldova
Published: April 2022

The research paper presents the results of the study on a stimulatory feeding of bees using natural chitosan polydisperse. It was found that the optimal dose of the natural chitosan polydisperse use is 2.0 ml of 3 % sugar syrup solution/L in bee feed. The use of the chitosan polydisperse in the stimulator feed during the autumn period on replenishment of reserves ensures an increase in immunity and winter hardiness by 15.09 %. During the spring period it increases bee family strength by 59,2 % and honey production by 97,8 % in the absence of a maintenance honey crop, which is more than the control group, or with 12.1 % and 19.2 % respectively – standard.
The violinist Serghei Lunchevici and the stylistic dimensions of his interpretative manner
Authors:   Academia de Muzică, Teatru și Arte Plastice, Republica Moldova, Brinzila-Cosleț Zinaida
Published: April 2022

The research of the stylistic originality of the interpretation of folk musical pieces by Serghei Lunchevici is an operation involved in the general analytical approach of our research, which aims to highlight maestro’s performing art and its specific features in general and, ultimately, its intrinsic value, their expressive and aesthetic valences. This article offers an analysis of the most important pearls in the folk repertoire of the formidable artist, whose interpretation for sure won the hearts of many listeners around the world.
Iraida Ciobanu, in the three hypostases of her self-affirmation
Authors:   Institutul Patrimoniului Cultural, Republica Moldova, Stavila Tudor
Published: April 2022

Iraida Ciobanu is one of the few plastic artists for whom her creations are synonymous with the genres she practices in painting – static nature and landscape, the most explored forms in rendering poetry and lyrics. Formed as an artist in the early `90s, the artist is devoted to these two genres throughout the time, approaching the landscape as an appeal to the memory arising from lyrical projections, oriented towards the past, while the static nature is a projection of future emotional states. Her works could reveal the following: the static nature returns to the present, being refreshed up by a unique and distinctive compositional, semantic and chromatic style. Moreover, as a professor of fine arts, as well as a scientific researcher concerned with the evolution of static nature as a genre in the post-war Moldovan fine arts, it ensures continuity. Nature and its inexhaustible beauties fully define the artist in a thematic aspect, she finding unique ways to discover continuity in her canvases.