bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of phenolic compounds in metabolism and their antioxidant potential
Authors: Silva Edson Pablo da , Herminio Vanessa Leal de Queiroz , Motta Daniel Nascimento , Soares Milena Botelho Pereira , Rodrigues Leticia de Alencar Pereira , Viana Josiane Dantas , Freitas Flavio Augusto de , Silva Aline Priscilla Gomes da , Souza Francisca das C. do Amaral , Vilas Boas Eduardo Valério de Barros
Published: August 2022

The intake of fruits and vegetables rich in nutrients with bioactive properties is associated with the prevention of a range of chronic diseases such as cardiovascular diseases, diabetes, and cancer that originate from physiological disorders, which can be promoted by the accumulation of free radicals in the body. Several chemical compounds with bioactive functions are found in fruits and vegetables. Among these, phenolic compounds stand out for having high antioxidant capacity. These compounds originate from the secondary metabolism of plants, being essential for their growth and reproduction. In addition, they can be more expressed by plants under stress conditions, such as infections by microorganisms, lesions, severe climate changes, nutritional deficiency, among others. The highest concentrations of these phenols are found in fruit and vegetable skins, due to their potential use in protecting against UV rays, pathogens and predators. The search for new sources of natural and/or synthesized antioxidants has been growing due to the wide biological activity observed for these compounds, such as the inhibition of lipid oxidation and its action against the inactivation of free radicals. These compounds can be synthesized via the shikimate/phenylpropanoid pathway. It is believed that after consumption they are partially degraded in the small intestine, about 5 to 10%, and the rest in the large intestine. Here we review how the plant synthesizes phenolic compounds and their health effects, demonstrating the significant dietary activity of these compounds in metabolic processes.
Progressão da doença renal crônica: análise comparativa da taxa de filtração glomerular em pacientes com hipertensão e/ou diabetes mellitus
Authors: Hauser Lorena Cristina Paintner , Hauser Marcus William , Batista André Luiz , Santos Celso Bilynkievycz dos , Alrai Omar Abdalalim
Published: August 2022

O rim humano possui diversas funções que devem estar em equilíbrio e harmonia para o bom funcionamento do organismo. Para avaliação da função renal individual pode-se calcular a taxa de filtração glomerular através de diversas fórmulas, dentre as quais destacamos Ckd-Epi e MDRD. Algumas comorbidades estão associadas à disfunção renal, como Hipertensão Arterial e Diabetes mellitus, e a progressão da disfunção renal impacta diretamente na qualidade de vida do doente. O presente estudo qualitativo, exploratório, retrospectivo e observacional visou identificar as comorbidades nos pacientes selecionados bem como a estratificação da função renal com base na fórmula Ckd-Epi. Ademais, o objetivo desse artigo é comparar a taxa de filtração glomerular em pacientes com doença renal crônica associada à hipertensão e/ou diabetes mellitus no decorrer do tempo estudado. Os dados presentes nesse trabalho foram retirados de prontuários eletrônicos presentes no sistema IPM saúde dos pacientes atendidos pelo sistema público de saúde de Cascavel/PR. Dessa forma, esses dados foram submetidos a Descoberta de Conhecimento em Base de Dados (DCAB) e a testes de análise de variância, com significância de α=0,05. Os estudos demonstraram uma redução média na taxa de filtração glomerular de 11,44%. Ao fim do estudo foi estabelecido o controle pressórico como critério importante a fim de se evitar a progressão da doença renal crônica. Além disso, não foi relacionado piora renal ao aumento dos níveis glicêmicos no grupo observado.
Mapeamento de pesquisas relacionadas aos veículos de superfície não tripulado (USV)
Authors: Cano Éric Vieira , Cano Priscila Lôpo Guimarães , Encina César Claudio Cáceres , Mioto Camila Leonardo , Ribeiro Alisson André , Paranhos Filho Antonio Conceição
Published: August 2022

Os veículos autônomos são utilizados há mais de 60 anos, com o avanço da tecnologia e novos enfoques desenvolveram-se os veículos de superfície não tripulados conhecidos como USV (Unmanned Surface Vehichle). Este estudo objetivou mapear quantitativamente as produções científicas relacionadas aos veículos de superfície não tripulados (USV, através de análise cienciométrica, destacando artigos e artigos de revisão desta área de conhecimento e demonstrando a quantidade de publicações até o ano de 2021. A partir de coletas de dados nas bases Scopus e Web of Science, foram realizadas exclusão de documentos duplicados e análises prévias dos títulos e resumos, gerando um portfólio geral de estudo com 1.190 publicações. O resultado deste mapeamento demonstrou que as pesquisas são focadas em tecnologias para a criação de veículos de superfície não tripulados (USV) com recursos avançados de controle e automação, e que continuam sendo desenvolvidas para o aperfeiçoamento do equipamento, pode-se perceber também que a produção sobre o tema seguirá em crescimento por ser um assunto relativamente novo e com grandes perspectivas para o desenvolvimento de novas pesquisas, métodos e aplicações. Por fim, espera-se que este estudo auxilie no mapeamento de pesquisas, principalmente sobre temas ainda pouco difundidos na ciência, para aumentar a visibilidade e compreensão sobre as inovações em pesquisas.
Macronutrient intake is not associated with cardiovascular risk assessed by Coronary Calcium Score, but dietary fiber showed a significantly inverse relationship
Authors: Cunha Natalia de Morais , Nagano Francisca Eugenia Zaina , Almeida Cássia Cristina Paes de , Magalhães Tiago Augusto , Formentini Franciane Silvana , Mezzomo Thais Regina , Cerci Rodrigo Julio , Lima Júnior Emilton
Published: August 2022

Evidence of impact of dietary factors on development of coronary artery calcification remains uncertain. The objective of the study was to evaluate the association between the intake carbohydrates, proteins, total fats, saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), polyunsaturated fatty acids (PUFA), trans fatty acids (TFA) cholesterol and fiber with cardiovascular risk. Cross-sectional analysis from 181 dyslipidemic patients. The Coronary Calcium Score (CCS) was used to measure cardiovascular risk. 24-hour recalls were applied and the Multiple Source Method was used to adjust dietary variability. The mean values of the cardiovascular risk categories were compared by analysis of variance, using ANOVA and Kruskal-Wallis. Tukey's post-test was used for multiple analyzes. Simple and multiple binary logistic regression, was used as a measure of association between nutrient intake and cardiovascular risk. Age, male gender, comorbidities and drug treatment were significantly prevalent in those with CCS>100. The average total energy intake was 1315.6 kcal. Total energy and macronutrient intake were higher among men (p < 0.05). No significant results were found regarding the association between cardiovascular risk and macronutrient intake. Fiber intake was inversely associated with cardiovascular risk, regardless of confusion factors (OR:0.918; 95% CI:0.845-0.999; p=0.047). The resultes that there was no association between nutrientes analyzed to cardiovascular risk assessed by CCS. However, the increase of dietary fiber intake in 1 g/day has been shown to reduce the of future cardiovascular events in 8.2% among individuals in the highest risk category. Therefore, we strongly recommend that fiber intake be encouraged.
Facilidades e dificuldades na comunicação entre profissionais de saúde e pacientes internados: percepção de pacientes
Authors: Cancilieri Rafhaela Fernanda Silva , Lima Fabiana Rodrigues , Ferreira Débora de Oliveira , Baliana Letícia Oliveira , Rezende Marina Pereira , Parreira Bibiane Dias Miranda , Goulart Bethania Ferreira
Published: August 2022

Objetivo: Identificar os fatores facilitadores e dificultadores para a comunicação com profissionais de saúde, na perspectiva de pacientes internados, na Clínica Médica, e descrever expectativas destes pacientes quanto à comunicação entre eles e os profissionais de saúde, durante a internação hospitalar. Métodos: estudo descritivo, com abordagem qualitativa. A pesquisa contou com 13 pacientes internados no setor de Clínica Médica de um Hospital de Ensino de Minas Gerais. A coleta de dados ocorreu por meio de entrevistas semiestruturadas áudio gravadas entre dezembro/2019 e janeiro/2020. Análise de dados seguiu a Análise de Conteúdo, modalidade temática. Resultados: emergiram três categorias temáticas: Despreparo do profissional de saúde, falta de diálogo e acolhimento frágil; Relação horizontal e dialógica entre profissional de saúde-paciente favorece a comunicação e Perspectivas do paciente em relação à comunicação com os profissionais de saúde, durante sua internação. As categorias temáticas revelaram as percepções dos pacientes, internados na Clínica Médica, quanto os aspectos facilitadores e dificuldades da sua comunicação junto aos profissionais de saúde, bem como suas expectativas quanto a esse processo comunicacional. Considerações Finais: respeito, diálogo, acolhimento e atenção são fundamentais para a base de uma comunicação efetiva. Entretanto, a falta deles constitui-se como barreira, impactando na relação de confiança entre profissional de saúde e paciente.
The improvement of the art of saving teeth by endodontic microsurgery - case report
Authors: Pereira Key Fabiano Souza , Silva Barbara Gabriela Cantieri da , Junqueira-Verardo Lia Beatriz , Vitoi Caio Henrique Bandeira , Santos Lais Mariá Ribeiro Chaves , Bruno Gustavo Julius Santos
Published: August 2022

The success of an endodontic surgery depends on the removal of a persistent infection from the external apical surface and necrotic tissue or contaminated filling material within the root canal system followed to a complete filling of the root end preparation. The current concepts of surgical endodontics recommend that its execution with the use of magnification and illumination of the operating microscope, which allows an easier identification of the root apices, small ostectomies and smaller apex resection angles. The objective of this article is to report and discuss a clinical case of endodontic microsurgery where the main resources currently recommended were used to increase the success in surgical endodontics. Based on specific equipments, instruments and materials the endodontic microsurgery increases the predictability of success of the surgery. Among the main advances compared to traditional surgery we could observe less trauma to the operated region which resulted in a faster and more comfortable healing for the patient.
Implantação, funcionamento e relevância do banco de dentes humanos para o ensino e pesquisa em Odontologia: disposições gerais
Authors: Cadilho Julio Cesar Ramos , Silva Warley Oliveira , Alves Flávio Rodrigues Ferreira
Published: August 2022

O Banco de Dentes Humanos (BDH) está presente em muitas instituições de ensino superior com cursos de Odontologia, e tem como propósito destinar dentes humanos extraídos para a pesquisa científica ou treinamento pré-clínico de acadêmicos, seguindo os mais elevados princípios éticos. O presente estudo trata-se de uma revisão de literatura sobre os  bancos de dentes nas instituições de ensino superior, com enfoque em sua importância, apresentando os parâmetros gerais para sua estruturação e funcionamento. O processo de implantação do Banco de Dentes requer além de espaço físico, um regulamento interno, equipamentos para adequação dos dentes, termos e documentos de consentimento e doação. A correta adequação física e química (desinfecção e armazenamento) dos dentes é fundamental para sua manipulação segura, mas não deve interferir nas suas propriedades estruturais. Neste contexto, a implantação do Banco de Dentes viabiliza práticas de ensino e pesquisas de maneira legalizada e segura, reduzindo o comércio ilegal de dentes e garantindo um destino significativo para os mesmos.
Principais evidências clínicas da oxigenoterapia hiperbárica no tratamento de úlceras de pé diabético: uma revisão sistemática
Authors: Eduardo Letícia de Sousa , Farias Maria Eduarda Gonçalves , Oliveira Camila Carvalho de , Souza Juliana Alves de , Ferreira Simone Barbosa da Silva , Ferreira Cynthia Lopes , Nascimento José William Araújo do
Published: August 2022

Objetivo: Analisar as principais evidências clínicas acerca do uso da oxigenoterapia hiperbárica no tratamento de úlceras de pé diabético. Metodologia: Trata-se de uma revisão sistemática realizada por meio do método PRISMA, nas bases de dados eletrônicas PubMed, Scopus e Web of Science, por meio dos seguintes descritores: “hyperbaric oxygenation” “diabetes”, “diabetic foot”, “leg ulcer” e “ischemia” Foram incluídos textos completos, disponíveis em português, inglês ou espanhol, publicados entre janeiro de 2016 a dezembro de 2021; os estudos precisavam avaliar a proporção de pessoas com úlceras de pé diabético cicatrizadas completamente em participantes randomizados para oxigenoterapia hiperbárica e em um grupo controle. Resultados: 08 artigos compuseram a amostra final desse estudo, com maior frequência de publicação em 2019 (n: 03). Todas as pesquisas apresentaram a metodologia do Ensaio Clínico Randomizado, apresentando nível de evidência forte (II). No geral, identificou-se que a taxa de amputação nos pacientes submetidos a oxigenoterapia hiperbárica foi inferior em relação ao tratamento padrão estabelecido nos ensaios clínicos. Três estudos relataram a redução da área da úlcera e cinco estudos mostraram que a oxigenoterapia hiperbárica aumentou a taxa de cicatrização das úlceras de pé diabético em relação ao tratamento convencional, com resultados estatisticamente significantes. Conclusão: As evidências atuais mostram algumas evidências da eficácia da
Produção científica brasileira em comportamento organizacional no período 2011 a 2020
Authors: Monteiro Lucilene Elayne Maria Machado , Kamada Mynerva Nunes , Garvão Rodrigo Fraga , Souza Gilvandro Figueiredo , Sousa Shirlaine Moraes e
Published: August 2022

Os estudos sobre o Comportamento Organizacional (CO) tem contribuído significativamente à consolidação da administração como ciência e o desenvolvimento gerencial das organizações. A construção de teorias, a fundamentação de análises e a compreensão do comportamento das pessoas nas organizações são elementos fundamentais para a construção do conhecimento nesta área. O objetivo deste trabalho consistiu em retratar os últimos 10 anos da evolução do campo de CO no Brasil, baseado no levantamento sistemático, análise e avaliação crítica da produção científica no período de 2011 a 2020, tendo por base uma pesquisa documental nos principais periódicos de Administração. Resultados apontaram que os pesquisadores tem como foco as pesquisas qualitativas, enquanto a abordagem se dividiu quase igualmente entre survey, pesquisa bibliográfica e estudos de caso, e os questionários e pesquisa documental são os meios de coleta de dados mais utilizados. Conclui-se que cada vez mais perde-se o interesse em publicar sobre o tema, visto que houve uma na quantidade de publicações a partir da metade da década.
Perfil epidemiológico da AIDS na terceira idade no município de Aracaju – Sergipe
Authors: Silva Eleni Maria da , Santos Beatriz Silva , Santos Gustavo Venicius da Silva , Freire Adão Renato de Jesus , Valentim Aislayne Rodrigues , Gomes Anna Letícia Ferreira , Camarço Maria Fernanda de Sá , Barros Fernanda Dantas , Gallotti Fernanda Costa Martins , Santos Deyse Mirelle Souza
Published: August 2022

Objetivo: Traçar a situação epidemiológica da Síndrome da Imunodeficiência Adquirida na terceira idade em Aracaju – Sergipe. Método: Trata-se de um estudo epidemiológico, tipo ecológico, descritivo, de cunho quantitativo, utilizou-se da busca por meio da análise dos dados a partir dos estratos populacionais do município de Aracaju do estado de Sergipe, aplicando métodos de análise, Sistema de Informação de Agravos de Notificação (SINAN) pertinentes aos casos notificados de AIDS na terceira idade entre 2010 a 2020. Resultados: Durante o período de estudo a distribuição dos casos de AIDS na população idosa no município de Aracaju/SE, no período de 2010 a 2020, foi notificado um total de 69 casos, onde houve maior predominância do sexo masculino representando um total de 51 casos (73,91%), enquanto que, o sexo feminino representou apenas 18 casos (26,09%). Foi aplicado o teste de Qui-Quadrado e obteve um p-valor < 0,05, com isso rejeitamos a H0 e concluímos que não existe associação entre as variáveis sexo e a faixa etária relacionado ao desenvolvimento da AIDS na terceira idade, ou seja, não houve diferença estatisticamente significativa entre as frequências analisadas. Conclusão: Dada à relevância da temática, constatou-se através do presente estudo a necessidade de aprimorar conhecimentos sobre as causas que propiciam o desenvolvimento da patologia e que contribuem para o crescente número de casos em pessoas idosas. Também, levar em consideração as variadas modificações nesse perfil epidemiológico que os tornam mais vulneráveis, cabendo a imposição de melhoria nos serviços de assistência à saúde.
Adoção e aceitação de tecnologia por pessoas idosas: um protocolo de revisão de escopo
Authors: Carvalho Juliana Cordeiro , Cipolli Gabriela Cabett , Cliquet Lilian Ourem Batista Vieira , Pessoa Lucas Parente , Cachioni Meire
Published: August 2022

Objetivo: Identificar a adoção e a aceitação do uso das tecnologias pelo público idoso.  métodos: A metodologia da Joanna Briggs Institute (JBI) será utilizada para buscar na literatura indexada nos idiomas publicados em inglês, espanhol e português. Serão coletadas em 20 bases de dados, as listas de referência dos estudos incluídos serão pesquisadas manualmente. Dois autores avaliarão os títulos, resumos e textos completos de forma independente de acordo com os critérios de elegibilidade. Um formulário de extração de dados customizado será utilizado para realizar a extração de dados dos estudos incluídos, que serão: (1) Estudos em inglês, português e espanhol; (2) estudos que envolvem pessoas idosas (60 anos ou mais) e que usem tecnologias; (3) estudos empíricos com dados quantitativos, transversais ou longitudinais, (4) cartas ao editor e editoriais, (5) publicados em todos os anos disponíveis (1993 a 2022). resultados: Os resultados serão apresentados em formato de tabela com resumo narrativo.
Agregação de valor ao Theobroma grandflorum pela elaboração de sorvete artesanal
Authors: Paula Nelio Ranieli Ferreira de , Sousa Isabela Oliveira de , Araújo Érica de Oliveira
Published: August 2022

O sorvete disponível comercialmente é, geralmente, pobre em antioxidantes naturais, sendo interessante a exploração de possibilidades que tendem a melhorar os atributos nutricionais do sorvete e agregação de valor ao produto. Diante do exposto, objetivou-se com o presente trabalho promover a agregação de valor ao cupuaçu (Theobroma grandfolium) por meio da elaboração de sorvete artesanal com diferentes concentrações da polpa. O delineamento experimental utilizado foi o inteiramente casualizado, constituído pelo desenvolvimento de quatro formulações de sorvete (10%, 15%, 20% e 35% concentração de polpa cupuaçu), com cinco repetições, perfazendo o total de 20 unidades experimentais. Os tratamentos durante e após o processamento foram submetidos às análises físico-químicas, sensorial e microbiológicas. Os resultados permitiram concluir que as análises físico-químicas da matéria-prima apresentam dentro da faixa adequada para a produção e agregação de valor ao cupuaçu. A adição de 15% de polpa de cupuaçu permite redução na acidez total, aumento no °Brix e nos atributos sensoriais de cor e textura, conferindo maior aceitabilidade pelo consumidor; enquanto que a adição de 35% de polpa de cupuaçu ao sorvete apresentou menor avaliação de aspecto global e intenção de compra. O processamento de sorvete na presença de polpa de fruta de cupuaçu, caracteriza-se como oportunidade de diversificação e agregação de valor a produção, melhoria quanto ao desenvolvimento de produtos regionais e garantia de segurança alimentar e nutricional, respeitando as normas de qualidade microbiológica.
Transtorno do uso de bebidas alcoólicas e fatores associados entre mulheres adultas
Authors: Estevão Flavia Quintanilha de Oliveira Leite , Souza Karoline Omizolo de , Zanovello Syssa Reino , Iahnn Stephanie Ramirez , Ditz Dan Graef , Lima Rosangela da Costa
Published: August 2022

O objetivo deste estudo foi estimar a prevalência do transtorno do uso do álcool entre a população adulta feminina residente na área urbana de Dourados, MS, Brasil, e avaliar a associação com fatores socioeconômicos, comportamentais e de saúde. Trata-se de um estudo seccional, de base populacional, com mulheres adultas de 20 a 59 anos. A amostragem foi feita por conglomerados em múltiplos estágios. O transtorno do uso do álcool foi avaliado a partir do Alcohol Use Disorder Identification Test (AUDIT), sendo positivo quando igual ou superior a 8. A análise estatística das informações foi realizada pelo Teste Qui-quadrado, Exato de Fisher, Tendência Linear e Regressão de Poisson. Das 597 mulheres entrevistadas, 12% apresentavam esse transtorno. Aquelas sem companheiro(a) apresentavam 10% a mais de prevalência de transtorno do uso do álcool do que as com companheiro(a); as tabagistas tiveram 25% a mais do que as não tabagistas, já aquelas com diagnóstico de hipertensão arterial sistêmica apresentaram 5% a menos do que as não hipertensas. A pesquisa indicou alta prevalência de transtorno do uso do álcool, o que indica que políticas de saúde precisam dar atenção a esse tema, especialmente para mulheres sozinhas, tabagistas e hipertensas, que foram as mais comprometidas neste estudo.
PENGARUH TINGKAT KEBERLANJUTAN SERTA REPUTASI KAP TERHADAP PERINGKAT KREDIT PERUSAHAAN
Authors:   Universitas Katolik Parahyangan Indonesia, Michael Michael , Djajadikerta Hamfri ,   Universitas Katolik Parahyangan Indonesia
Published: August 2022

Research Purposes. This study aims to determine the impact of the level of sustainability and reputation of KAP that can affect the assessment results of the credit rating process carried out by PEFINDO. Research Methods. In this study, the ordinal logistic regression analysis model is used to determine the probability of obtaining a credit rating for a company. Financial variable is described through level of sustainability prediction as calculated by using the value of the Altman Z-Score, while non-financial variable is described through the reputation of the KAP. There were 25 samples of companies that obtained credit ratings in a row from 2014 to 2018 by PEFINDO tested in this study. Research Result and Findings. The results of this study state that the level of sustainability prediction has a positive effect; whilst KAP reputation, which are not affiliated with Big 4, has a negative effect on the results of companies' credit ratings
THE DETERMINANTS OF TAX COMPLIANCE: LOVING OR FEARING
Authors:   Universitas Tadulako Indonesia, Mayapada Arung Gihna , Muliati Muliati ,   Universitas Tadulako Indonesia, Tampang Tampang ,   Universitas Tadulako Indonesia, Djaniba Erlina ,   Universitas Tadulako Indonesia
Published: August 2022

Research Purposes. This study aims to analyze the internal and external determinants of tax compliance. The internal determinant in this study is a feeling of love for the motherland which is manifested through the soul of patriotism and nationalism. Meanwhile, external determinants that cause fear of taxpayers are tax sanctions. Research Methods. The type of this research is quantitative research. The research data was obtained by distributing questionnaires to all individual taxpayers registered at the Tax Office of Palu. The sampling method is used a random sampling technique so that the total sample of this study is 94 respondents. The data analysis method used in this study is multiple linear regression analysis. Research Results and Findings. The results show that the spirit of patriotism does not affect taxpayers to comply with tax regulations. Meanwhile, nationalism has a significant effect on tax compliance. Meanwhile, tax sanctions have proven unable to increase tax compliance. The findings of this study have implications for the economic theory of tax compliance and social identity theory.
Design Guidelines Konservasi Sempadan Sungai Kampung Lengkong Kyai, Tangerang-Banten
Authors: Khamdevi Muhammar
Published: August 2022

Lengkong Kyai Village is located in the middle of BSD City and on the banks of the Cisadane River. This village is a historical heritage village, which was determined by the Tangerang Regency. The condition of the river border of this village has experienced significant erosion due to river flooding and the condition of the border vegetation as a barrier is decreasing. This will endanger the existence of this village in the future. Therefore, it is necessary to plan a principle and concept of river border conservation that is environmentally friendly and sustainable. This research uses a qualitative approach and produces a combination of active and passive conservation design principles and guidelines, so that local residents can be directly involved in conserving their village's wetlands river boundaries and also maintaining the cleanliness and clarity of river water.
The Association of Serum Progesterone Levels on Day of Oocyte Retrieval with Pregnancy Outcome
Authors: Garg Parul
Published: August 2022

Aims and Objectives: To establish the level of serum progesterone (P4) on the day of oocyte retrieval beyond which it can affect the outcome of in vitro fertilisation (IVF), and to further establish the incidence of serum P4 rise in an agonist and antagonist cycle.

Methods: This prospective observational cohort study was conducted from November 2020 to November 2021 at the Sarvodaya Fertility and IVF Centre, Delhi, India. For this study, the author recruited 352 couples with infertility who were treated with IVF/intracytoplasmic sperm injection-embryo transfer, of which 279 patients completed an IVF/intracytoplasmic sperm injection-embryo transfer cycle during the study period and were included in the final analysis.

The standard gonadotropin-releasing hormone antagonist (fixed or variable) and long gonadotropin-releasing hormone agonist controlled ovarian stimulation protocols were used in all patients. Participants were recruited if they were undergoing controlled ovarian stimulation with all gonadotropins, recombinant follicle-stimulating hormone/urinary human menopausal gonadotropin, or recombinant luteinising hormone. The study population was sub-grouped into two groups according to their P4 level on day of oocyte retrieval (calculated according to receiver operating characteristics curve): Group A (p≤11.6 ng/dL; n=247 out of 27; 88.5%) and Group B (p>11.6 ng/dL; n=32 out of 279; 11.5%). Statistical analysis was performed with the Statistical Package for Social Sciences (SPSS) 17.0 version (IBM, New York City, New York, USA).

Results: The percentage of patients with a rise in P4 on the day of oocyte retrieval were found significantly more in the antagonist protocol (13.3% [24 out of 181]) than in the agonist protocol (8.2% [8 out of 98]; p=0.04). Pregnancy rate was significantly higher in Group A (39.3% [97 out of 247]) compared with Group B (12.5% [4 out of 32]). The clinical pregnancy rate was also significantly higher in Group A (34.4% [85 out of 247]) compared with Group B (6.3% [2 out of 32]).

Conclusion: Patients with higher levels of P4 (>11.6 ng/mL) were associated with lower pregnancy and clinical pregnancy rates.
As empregadas domésticas e a COVID-19: interseccionalidades, pandemia e o "novo normal"
Authors: Esteves Soares Pollyana , Lourinho Bouth Camila
Published: August 2022

A pandemia de COVID-19 foi responsável por agravar a precarização e vulnerabilidade das empregadas domésticas, afetando diversas áreas de suas vidas e as suas garantias a direitos sociais. Portanto, discute-se a realidade do trabalho doméstico remunerado no Brasil a partir de suas intersecções e desigualdades, haja vista a herança colonial que o país carrega. Embora essa pesquisa tenha sido realizada após dois anos do início da pandemia, sua pertinência reside na necessidade de contextualização de todas as fases vividas nesse momento de crise, desde as medidas emergenciais, ao início do afrouxamento e até o momento presente, onde retornamos ao “novo normal”. Para isso, o objetivo da pesquisa consiste em demonstrar que, em contexto pandêmico, as interseccionalidades influenciam nas condições econômicas, na força de trabalho e na proteção dos direitos sociais das empregadas domésticas. Para tanto, foi traçada abordagem hipotético-dedutiva, por métodos de revisão bibliográfica-documental e da análise de dados. Os resultados alcançados permitem inferir que a pandemia trouxe prejuízos econômicos e custos sociais, gerando novos problemas e agravando outros implícitos e naturalizados, como a desigualdade, a desvalorização do trabalho doméstico e legitimação dessa pelo Estado, o trabalho análogo ao de escravo e a ausência de políticas públicas voltadas a essas mulheres. Logo, conclui-se que o “novo normal” não possui caráter de novidade como anunciado.
Gambaran Skala Nyeri Akibat Penurunan Kekuatan Otot Gastrocnemius pada Lansia Pekerja di Posyandu Lansia Pekajangan Gang 16
Authors: Nurseptiani Dzikra , Setyawan Muhammad Ghilang Maulud , Izzati Naila
Published: August 2022

Lansia adalah sekelompok orang dengan usia diatas 60 tahun yang sedang mengalami suatu proses perubahan bertahap dalam jangka waktu beberapa dekade. Fase lansia akan mengalami perubahan-perubahan anatomis khususnya pada sistem muskuloskeletal diantaranya nyeri yang sering timbul di daerah extremitas bawah yaitu pada otot gastrocnemius sehingga akan terjadi penurunan kekuatan otot. Nyeri pada muscle gastrocnemius dapat diukur menggunakan alat ukur nyeri Numering Rating Scale (NRS) dan untuk penurunan kekuatan otot yang terjadi akibat adanya nyeri pada gstrocnemius dapat diukur menggunakan Manual Muscle Testing (MMT). Tujuan dalam penelitian ini adalah untuk mengetahui tingkat nyeri yang diakibatkan karena penurunan dari kekuatan otot gastrocnemius pada lansia pekerja di posyandu lansia Pekajangan Gang 16. Metode dalam penelitian deskriptif kuantitatif ini menggunakan data primer yaitu usia, jenis kelamin dan pekerjaan dengan menggunakan kuisioner serta wawancara secara langsung kepada 20 narasumber. Selanjutnya melakukan pengukuran nyeri dan penurunan kekuatan otot gastrocnemius. Hasil yang didapat dari penelitian ini setelah melakukan wawancara, pembagian kuisioner dan pengukuran nyeri serta penurunan kekuatan otot terbukti bahwa pada umur diatas 65-69 tahun adalah yang paling banyak terjadi dengan jenis kelamin perempuan yang lebih banyak dibandingkan dengan laki-laki. Selain itu, karakteristik pekerjaan sebagai buruh juga mempunyai risiko lebih tinggi terjadi nyeri dan penurunan kekuatan otot gastrocnemius karena masa kerja yang jauh lebih lama dibandingkan dengan pedagang. Untuk karakteristik nyeri sendiri rerata lansia mengalami penurunan kekuatan otot grade 2 dan nyeri yang dirasakan ada di skala 8. Simpulan dari penelitian ini bahwa lansia akan mengalami perubahan neuromuskular dan muskuloskeletal yang terjadi pada fase tersebut berupa menurunnya kekuatan otot yang dapat terjadi rasa nyeri pada muscle gastrocnemius.
Comparative Screening of Hybrids and Synthetic Maize (Zea mays L.) Cultivars for Drought-Sensitive and Drought-Tolerant Under Different Irrigation Regimes
Authors: Shah Muhammad Nadeem , Hussain Shabir , Ali Hakoomat , Khan Mehrab , Jamil Humaira , Bukhari Anum , Ali Shahkar , Naveed Muhammad , Sohail Muhammad
Published: August 2022

Water scarcity is the most serious issue in crop production around the globe. Because of less water availability, various breeding and agronomic management techniques are being used to cope with this issue. For this purpose, a pot experiment was performed to screen hybrids and synthetic maize cultivars for drought-tolerance under various irrigation regimes at green-house of Agronomic Research Farm, Bahauddin Zakariya University, Multan, Pakistan during 2017. Experimental treatments comprise five maize hybrids viz. H1=DK-6317, H2=DK-6724, H3=P-1543, H4=P-1429, and H5= P-1574 and three locally synthetic maize cultivars viz. S1= Neelum, S2= Pak- Afghoi, and S3= Sadaf and three irrigation regimes viz. Control (CK) =80%WHC (water holding capacity), low drought (LD) =60% WHC and severe drought (SD) =40% WHC. It was resulted that irrigation regimes significantly affect growth and plant water relation. Results regarding maize hybrids growth showed that maximum plant height (5.20, 46.8 and 38.77 cm), number of leaves (6.41, 6.19, and 5.65), leaf area per plant (415.5, 361.5 and 305.8 cm2), dry weight of shoot per plant (6.09, 5.09 and 4.39 g) and dry weight of root per plant (0.85, 0.82 and 0.78 g) was obtained from DK-6724 under CK, LD and SD, respectively.  While the minimum plant height (45.23, 36.47 and 28.87 cm), number of leaves (5.38, 5.05 and 4.79), leaf area per plant (11.87, 10.99 and 10.01 cm2), dry weight of shoot per plant (5.71, 4.75 and 4.02 g) and dry weight of root per plant (0.66, 0.63 and 0.61 g) was measured in P-1429 under CK, LD and SD, respectively. Likewise, in synthetic cultivars, Neelum performed well followed by Pak-Afghoi and Sadaf in all irrigation regimes. Results regarding plant water relation revealed that DK-6724 and Neelum maintained their osmotic potential and are considered as drought-tolerant. While P-1429 and Sadaf could not maintain their osmotic potential and were considered as drought-sensitive under normal and drought stress.
Analisis Konsep Feng Shui Dan Rokuyo Pada Novel Jisatsu Yoteibi Karya Akiyoshi Rikako
Authors: Prameswary Nadia , Fitriana Rina , Mugiyanti Mugiyanti
Published: August 2022

Penelitian ini bertujuan untuk mendeskripsikan struktur Intrinsik dalam Novel Jisatsu YoteiBi karya Akiyoshi Rikako. Unsur-unsur intrinsik yang dibahas adalah tokoh, penokohan serta Pemplotan. Mendeskripsikan Konsep Fengshui dan Rokuyo, serta Dampak Negatif dan Positif percaya Feng shui dan Rokuyo dalam tokoh Utama dalam Novel Jisatsu YoteiBi karya Akiyoshi Rikako. Penelitian ini menggunakan metode penelitian deskriptif yaitu, mengungkapkan dan menjelaskan data dengan memberi deskripsi pada objek dengan apa adanya. Skripsi ini menggunakan teknik kepustakaan, yaitu dengan membaca buku yang berhubungan dengan karya sastra, psikologi kepribadian, kamus serta internet. Hasil penelitian ini menunjukkan bahwa tokoh utama mempelajari Feng shui dan Rokuyo dari dengan apa yang Tokoh Utama lihat untuk dilakukan dalam kehidupan sehari-hari. Dengan mempercayai Feng shui dan Rokuyo Tokoh utama mendapatkan Dampak Positif Dan Negatif dalam kehidupan sehari-hari.
Dongeng sebagai Media Pencitraan Perempuan dalam Budaya Patriarkat
Authors: Fitriarti Karunia , Trisari Agatha
Published: August 2022

Stigma negatif sudah melekat dalam diri perempuan. Hal ini tergambar dalam dongeng. Perempuan harus mengikuti stereotipe agar bisa dapat dianggap normal dan diakui oleh masyarakat. Perempuan diharuskan untuk pasrah dan tidak berdaya. Namun, jika perempuan berpendirian, ia dianggap manipulatif dan jahat. Padahal, perempuan adalah sosok penting dan berpengaruh dalam pewarisan dongeng dari satu generasi ke generasi. Hal tersebut terjadi karena budaya patriarkat yang terdapat di masyarakat. Penelitian ini bertujuan menganalisis citra perempuan di dalam dongeng Grimm Bersuadara dan dongen nusantara. Penelitian ini menggunakan metode kualitatif deskriptif. Penelitian ini menyimpulkan bahwa penggambaran seorang perempuan di dalam dongeng merepresentasikan ketidakberdayaan dirinya atas dominasi yang dilakukan oleh laki-laki.
Ekranisasi Novel Wedding Agreement Karya Mia Chuz
Authors: Dinni Alfiya , Mubarok Zaky
Published: August 2022

Penelitian ini bertujuan mendeskripsikan proses transformasi dari novel ke film yang berpengaruh pada alur, tokoh, dan latar baik, dalam bentuk kategorisasi aspek penciutan, penambahan, maupun perubahan bervariasi dalam novel Wedding Agreement karya Mia Chuz. Penelitian ini menggunakan metode deskriptif kualitatif. Data diperoleh dengan membaca, menonton, dan mencatat. Hasil penelitian ini menunjukkan bahwa transformasi novel ke film berpengaruh pada alur, tokoh, dan latar. Terdapat penciutan, penambaham, dan perubahan bervariasi dalam film. Penciutan alur, tokoh, dan latar terjadi karena media yang digunakan dalam pembuatan novel dan film berbeda. Secara keseluruhan, penciutan terjadi karena penghilangan cerita, tokoh, dan latar diambil pada bagian yang tidak begitu penting untuk divisualisasikan. Penambahan alur, tokoh, dan latar dalam film masih relevan dengan cerita. Visualisasi film dibuat lebih menarik dengan banyaknya konflik cerita. Tokoh dan latar tambahan dimunculkan sehingga cerita dalam film tidak monoton. Kemunculan tersebut untuk menambah esensi film sehingga penonton akan terbawa masuk dalam alur cerita. Alur, tokoh, dan latar yang dilakukan dalam visualisasinya masih relevan dengan novel.
Need for HTA supported risk factor screening for hypertension and diabetes in Nepal: A systematic scoping review
Authors: Adhikari Chiranjivi , Dhakal Rojana , Adhikari Lal Mani , Parajuli Bijaya , Subedi Khem Raj , Aryal Yeshoda , Thapa Arjun Kumar , Shah Komal
Published: August 2022

Objective

Health Technology Assessment (HTA) is a comprehensive and important tool for assessment and decision-making in public health and healthcare practice. It is recommended by the WHO and has been applied in practice in many countries, mostly the developed ones. HTA might be an important tool to achieve universal health coverage (UHC), especially beneficial to low-and-middle-income countries (LMIC). Even though the Package for Essential Non-communicable Diseases (PEN) has already been initiated, there is a clear policy gap in the HTA of any health device, service, or procedure, including the assessment of cardiovascular risk factors (CVRFs) in Nepal. Hence, we carried out the review to document the HTA supported evidence of hypertension and diabetes screening, as CVRFs in Nepal.

Materials and methods

We searched in PubMed, Cochrane, and Google Scholar, along with some gray literature published in the last 6 years (2016–2021) in a systematic way with a controlled vocabulary using a well-designed and pilot tested search strategy, screened them, and a total of 53 articles and reports that matched the screening criteria were included for the review. We then, extracted the data in a pre-designed MS-Excel format, first in one, and then, from it, in two, with more specific data.

Results

Of 53 included studies, we reported the prevalence and/or proportion of hypertension and diabetes with various denominators. Furthermore, HTA-related findings such as cost, validity, alternative tool or technology, awareness, and intervention effectiveness have been documented and discussed further, however, not summarized due to their sparingness.

Conclusion

Overall, the prevalence of DM (4.4–18.8%) and HTN (17.2–70.0%) was reported in most studies, with a few, covering other aspects of HTA of DM/HTN. A national policy for establishing an HTA agency and some immediately implementable actions are highly recommended.
Associations between obesity parameters and the risk of incident atrial fibrillation and ischaemic stroke in the different age groups
Authors: Ahn Hyo-Jeong , Lee So-Ryoung , Choi Eue-Keun , Han Kyung-Do , Rhee Tae-Min , Kwon Soonil , Kim Sunwha , Oh Seil , Lip Gregory Y. H.
Published: August 2022

Objective

Obesity and aging are important predisposing factors to atrial fibrillation (AF) and ischaemic stroke (IS). However, limited data comprehensively evaluated the relationships between obesity measurements and AF and IS in different ages.

Methods

A total of 9,432,332 adults from the Korean National Health Insurance Service Database were included. The study population was categorized into the six age subgroups by an increase every decade from the twenties. We evaluated AF and IS risk according to body mass index (BMI) and waist circumference (WC) in the different age groups.

Results

During a mean follow-up of 8.2 ± 1.0 years, BMI-AF presented a J-shaped association across ages. The highest hazard ratio (HR) of the BMI ≥ 30 kg/m2 group was observed in subjects aged 30–39 years [HR 1.80, 95% CI 1.63–1.98, p < 0.001]. Underweight adults over 60 years also presented an increased AF risk. Incident IS risk increased in those with BMI over the normal range in early and midlife, but the association became obscured in adults aged > 60 years. Among the BMI ≥ 30 kg/m2 groups, subjects aged 20–29 years presented the highest risk of IS [HR 3.00, 95% CI (2.34–3.84), p < 0.001]. Overall, WC-AF and WC-IS showed positive linear correlations, but the WC-IS association was weak in subjects aged ≥ 40 years.

Conclusion

The higher risks of AF and IS according to an increment of BMI and WC were most apparent among the young ages. The association between obesity measurements and IS was not significantly above the midlife. Weight management in the young and integrated risk factor management in the elderly are warranted.
Impact of preexisting diabetes mellitus on cardiovascular and all-cause mortality in patients with atrial fibrillation: A meta-analysis
Authors: Xu Juan , Sun Yimeng , Gong Dandan , Fan Yu
Published: August 2022

Objective

To determine the impact of preexisting diabetes mellitus on cardiovascular and all-cause mortality in patients with atrial fibrillation (AF) by conducting a meta-analysis.

Methods

PubMed and Embase databases were comprehensively searched for relevant studies publishing until May 19, 2022. Cohort studies or post-hoc analyses of clinical trials that investigated the association of diabetes mellitus with cardiovascular or all-cause mortality in AF patients were included.

Results

A total of 21 studies with 526,136 AF patients were identified. The pooled prevalence of diabetes mellitus in patients with AF was 26%. The summary multivariable-adjusted risk ratio (RR) of all-cause mortality was 1.37 (95% confidence intervals [CIs] 1.23–1.53) for patients with diabetes versus those without diabetes. Moreover, diabetes mellitus was also associated with an increased risk of cardiovascular mortality (RR 1.46; 95% CI 1.34–1.58). Stratified analyses suggested that the impact of diabetes on all-cause and cardiovascular mortality was consistently observed in each named subgroup.

Conclusion

The presence of diabetes mellitus in patients with AF is associated with an increased risk of cardiovascular and all-cause mortality, even after adjustment for important confounding factors.
Case Report: Uncommon cause of limp in the 21st century
Authors: Thiemann Stephanie , Cimorelli Valeria , Bajwa Nadia M.
Published: August 2022

Scurvy results from a deficiency of ascorbic acid. This disease first appeared in children during the 19th century with the emergence of new dietary habits; in particular, heating milk that leads to a loss of ascorbic acid. Even though scurvy has become a rare condition in western countries, many cases are still reported in pediatric patients, especially in those who lack proper nutrition due to neurological or psychiatric illnesses. Symptoms include bleeding and swollen gums, loosening of teeth, bone abnormalities, arthralgia, delayed wound healing, anemia, petechiae, and purpura. Bone lesions are mainly irregularities of long bones metaphyses. We report the case of a five-year-old boy who presented with arthralgia and limb deformation (genu valgum). The patient was investigated for vitamin deficiencies to exclude rickets. The radiologic investigations revealed metaphyseal signs compatible with scurvy. During the hospitalization, the patient was observed to have abnormal eating patterns and the scurvy was attributed to malnutrition. Although the occurrence of scurvy is rare, it remains essential to detect this disease in children at risk of developing vitamin deficiencies. Without targeted treatment, the complications of scurvy can be serious and potentially fatal.
Abortion as an Essential Health Service in Latin America During the COVID-19 Pandemic
Authors: Ramón Michel Agustina , Ariza Navarrete Sonia , Chávez Susana
Published: August 2022

Background

The rapid increase in demand for health services as a result of the COVID-19 outbreak has created significant challenges for health systems. National and international health authorities have declared reproductive health services as essential, particularly those related to prevention, care during pregnancy, delivery and postpartum, as well as abortion services. This research was conducted by a regional team in cooperation with nine local organizations that are members of the Latin American Consortium against Unsafe Abortion (Consorcio Latinoamericano Contra el Aborto Inseguro, CLACAI).

Objectives

Our research aimed to examine the provision of reproductive healthcare services, with a focus on abortion, in nine countries during the first few months of the pandemic (March to September 2020).

Methods

Our research design developed a set of quantitative and qualitative indicators to monitor the availability and accessibility of abortion services during the COVID-19 pandemic. Researchers collected the quantitative data by reviewing regulations and other documents, government and civil society reports, and official statistics; the qualitative data was acquired through interviews with key actors, and non-representative surveys completed by healthcare professional and end users of reproductive services.

Results

Although six of the nine countries we researched deemed reproductive health services essential, only two of these six countries considered abortion services to be essential, and all nine countries reported difficulties in accessing abortion services. Restrictive abortion laws remained in place in the majority of countries (seven), and as a result access to abortion services became even more limited than it had been before the pandemic. At the same time, good practices to facilitate access to abortion services in healthcare facilities, updated regulatory frameworks, and collaboration between civil society and government agencies were identified and should continue to be promoted even after the pandemic crisis has subsided.

Conclusions

The pandemic catalyzed what was already happening in each country, and as such abortion services have become more accessible in countries like Argentina, where the so-called green wave has been generating social, legal and policy changes, whereas in countries such as Ecuador, where abortion is legally restricted and opposed to by the government, access to safe abortion became even more difficult than it was before the pandemic. However, the general trend has been a lack of adequate adaptation in order to guarantee quality in abortion care. That said, there have also been some interesting and positive service provision initiatives, such as telemedicine, implemented in at least two countries, which, if maintained long-term, could improve access to safe abortion.