bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-Term Maintenance of Inhibition Training Effects in Older Adults: 1- and 3-Year Follow-Up
Authors: Wilkinson Andrea J. , Yang Lixia
Published: November 2022

Objectives: The aim of this study is to examine the long-term maintenance of training benefits in inhibition, as measured with the Stroop task, in older adults over 1- and 3-year periods. Methods: Participants from an original 6-session Stroop training study (Wilkinson & Yang, 2012 [Wilkinson, A. J., & Yang, L. (2012). Plasticity of inhibition in older adults: Retest practice and transfer effects. Psychology and Aging, 27, 606–615. doi:10.1037/a0025926]) were invited to come back to the lab to complete a single session of the Stroop task at 2 different time points. Thirty-three older adults returned for the 1-year follow-up session, and 26 of them returned for the 3-year follow-up session. Results: The results revealed maintenance of the training-induced inhibition gains at both follow-up sessions. Furthermore, performance at the 2 follow-up sessions was better (i.e., reduced Stroop ratio interference score) than baseline level. Discussion: The findings demonstrate the durability of inhibition training gains in older adults for up to a 3-year period. These results further extend the literature on long-term maintenance of cognitive training benefits in older adults by examining the durability of training effects in inhibition, an important executive function, and by covering a substantial maintenance period (i.e., up to 3 years). 
PENGARUH NILAI PELANGGAN DAN KUALITAS LAYANAN TERHADAP KEPUASAN PELANGGAN JASA TRAVEL BATURAJA
Authors: Maharani Septia , Dari Wulan
Published: November 2022

Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh nilai pelanggan dan kualitas layanan terhadap kepuasan pelanggan pada jasa travel Baturaja.
Desain/metodologi/pendekatan penelitian : Jenis penelitian yang digunakan adalah kuantitatif menggunakan metode survey dengan memberikan kuisioner kepada beberapa responden dengan beberapa pertanyaan untuk dijawab di dalam google form sebanyak 12 pertanyaan yang berkaitan dengan indikator variabel yang diteliti yaitu 3 variabel yaitu nilai pelanggan, kualitas layanan dan kepuasan pelanggan. Lokasi penelitian di daerah Baturaja Sumatera Selatan. Populasi dalam penelitian ini diambil dari pelanggan jasa travel baturaja. Sample yang diambil yaitu 50 responden dengan kriteria yang memiliki intensitas transaksi minimal sebanyak 4  kali  dalam 3 bulan terakhir merupakan sampel yang dipilih. Selanjutnya menggunakan metode analisis linier satu variabel indipenden.
Hasil penelitian : Berdasarkan hasil pengolahan data statistik dengan menguji valitidas dan reliabilitas dari data yang didapat bahwa kualitas layananan yang telah diberikan sudah baik. Selanjutya berdasarkan hasil analisis regresi linier satu variabel indipenden, diperoleh hasil bahwa masing-masing variabel nilai pelanggan (x1) kualitas layanan (x2) dan kepuasan pelanggan (y) memiliki nilai sig dibawah 0,05 dan dapat disimpulkan bahwa pengaruh nilai pelanggan dan kualitas layanan terhadap kepuasan pelanggan adalah signifikan.
Implikasi hasil penelitian : Kualitas layanan merupakan faktor yang menjadi penentu kepuasan pelanggan, semakin baik kualitas layanan maka semakin tinggi tingkat kepuasan pelanggan.
Effectiveness of masks in the suppression of COVID-19 cases during the ongoing pandemic in India
Authors: GANESH SHREYAS , KHYUM MIRZA M.O. , KIKANME KENNETH N. , RAMKUMAR SESHADRI
Published: November 2022

Perhaps the worst predicament faced by humanity in the twenty-first century is the COVID-19 pandemic, which is caused by the SARS-CoV-2 virus. Most parts of the world, including India, went into lockdowns for some period because of the massive increase in cases throughout 2020. Face masks became an important counter-measure for protecting the populace, health professionals, and medics, particularly during the period prior to the mass availability of vaccines.
This study intends to evaluate the effectiveness of face masks in limiting the spread of the virus. The data for the number of COVID-19 cases was analyzed from January 1, 2022 to May 31, 2022, using Python programming. This timeframe involved face mask mandates and no mask requirement, and hence was considered to be ideal for analyz-ing the usefulness of face masks. A decline in cases during the mandate was observed, while the opposite occurred without the mandate. The outcome of the research showed that face masks are effective additional measures against the spread of SARS-CoV-2. This study elevates the value of personal protective equipment (PPE), such as face masks, made with nonwovens and other fabrics, as lifesavers in the case of airborne diseases such as COVID-19 and other pulmonary disorders.
Effects of orders of addition in nanocellulose–cationic starch– colloidal silica systems for papermaking
Authors: LEIB BRANDON D. , GARLAND LARDEN J. , BARRIOS NELSON A. , HUBBE MARTIN A.
Published: November 2022

Two orders of addition were compared when preparing paper handsheets from recycled copy paper furnish in combination with nanofibrillated cellulose (NFC), cationic starch, colloidal silica, and cationic retention aid (cPAM; cationic polyacrylamide). Faster dewatering and higher fine-particle retention were obtained at equal optimized dosages of additives when the colloidal silica was added last, after addition of the cPAM. The same order of addition also provided a higher gain in the paper’s tensile strength. However, higher paper stiffness was achieved when the colloidal silica was instead added to the NFC, after its pretreatment with cationic starch. Results were consistent with the principle that papermaking additives added shortly before sheetforming tend to have the largest effects on drainage and retention. The results also demonstrated a sensitivity to the relative dosages of positively and negatively charged additives.
One Year In: What I Learned in My First Year of Librarianship and What I Wish I Would Have Done Differently
Authors: LaPreze Dani
Published: November 2022

This paper ruminates on my first year as an academic librarian on a health sciences campus. Discussed topics include lessons that were learned, reflection on what I wish would have happened differently, and nominal but helpful advice for recent graduates with little experience in libraries or those making a career transition into librarianship.
Review of the community college library: reference and instruction
Authors: Macleod Kaia
Published: November 2022

Review of Pinkley, J., and Casey, K. (Eds) (2022). The Community College Library: Reference and Instruction. Association of College and Research Libraries.
Autonomy, Posthuman Care, and Romantic Human-Android Relationships in Cassandra Rose Clarke’s The Mad Scientist’s Daughter
Authors: Sousa Monica
Published: November 2022

This essay looks at the representations of romantic relationships between humans and intelligent androids in Cassandra Rose Clarke’s science fiction novel, The Mad Scientist’s Daughter (2013). Clarke’s novel encourages readers to re-evaluate common fears surrounding human-interaction. By closely looking at this novel, this essay offers a posthuman care-ethical approach. This essay argues that in depictions of romances between humans and androids, posthuman intimacies can reaffirm a humanity that is shaped by care when attention is given to autonomy. This care ethic suggests a posthumanist vision of humanity that requires trying to understand and be willing to learn more about the feelings and choices of a nonhuman being – even if those feelings and choices are artificially simulated.
“Woman has won”; “(Venus won)”: On Donna Haraway’s Goddess
Authors: Theuma Maria
Published: November 2022

The concluding words of Donna J. Haraway’s essay ‘A Cyborg Manifesto’ read, “I would rather be a cyborg than a goddess”. In this article, I aim to determine the extent to which that declaration implicates the question of the female body in representation—particularly, the goddess’s. Building on existing work that examines the female body in relation to the tradition of the nude in painting, I explore the possibility of assigning an identity to the goddess that Haraway chooses the cyborg over—specifically that of Venus, the mythological goddess of love and beauty, which I further read within the framework offered by the collaborative exchange between Haraway and the artist Lynn Randolph. In light of this, I position the cyborg and goddess within a certain vision of the relationship between women, nature and technology. In my conclusion, I call for a consideration of the possibility of a posthuman goddess.
Morton, T. & Boyer, D (2021). Hyposubjects: On becoming human. Open Humanities Press.
Authors: Robertson Nicola
Published: November 2022

In the opening of their book Hyposubjects: On becoming human, Morton and Boyer (2021) prepare their reader that “what follows is an exercise in flimsy and chaotic thinking” (13). As introductions go, it is certainly unusual, irreverent and an astute assessment of how the book unfolds.
A fast converging sampling operator
Authors: Draganov Borislav
Published: November 2022

We construct a sampling operator with the property that the smoother a function is, the faster its approximation is. We establish a direct estimate and a weak converse estimate of its rate of approximation in the uniform norm by means of a modulus of smoothness and a $K$-functional. The case of weighted approximation is also considered. The weights are positive and power-type with non-positive exponents at infinity. This sampling operator preserves every algebraic polynomial.
Microbiota intestinal en perros con gastroenteritis hemorrágica aguda
Authors: Gárate Machuca Christian Andrés , Armas Ariza Juan Carlos
Published: November 2022

Introducción. La microbiota intestinal (MI) está compuesta por un conjunto de bacterias, que producen metabolitos que influyen en la salud del hospedador. Las alteraciones en su diversidad y composición se conocen como disbiosis. Objetivo. Identificar la microbiota intestinal en caninos con cuadros de gastroenteritis hemorrágica aguda. Metodología. Se analizaron las heces de 10 caninos, mediante cultivos bacteriológicos estándar y su valoración cualitativa mediante coproparasitarios directos. Resultados. El 69,4% de bacterias aisladas forman parte de la microbiota intestinal normal, en su mayoría bacterias de la familia Enterobacteriaceae, y en el 30,6% se aislaron bacterias consideradas patógenas (Shigella 23% y Aeromona hydrophila 7,6%). En el 100% de las muestras en la evaluación directa se reportó un incremento en la microbiota intestinal. Conclusiones. Los cultivos bacteriológicos no permitieron identificar todas las bacterias presentes en las heces, mientras que la evaluación directa si permitió identificar alteraciones en la cantidad de bacterias, determinando estados de disbiosis en menor tiempo. El diagnóstico molecular permitiría la identificación de todas las bacterias presentes, tanto en pacientes sanos como en pacientes con enfermedades gastroentéricas.
Telemedicine : New Era of Health Service
Authors: Hossain Md Iqbal , Akter Nasima , Rahman Abdur
Published: November 2022

Telemedicine has the potential to help facilitate the delivery of health services to rural and remote areas. In somecircumstances, telemedicine may also be useful for the delivery of education and teaching programmes and the facilitation of administrative meetings. In this paper reference is made to a variety of telemedicine applications. An overriding imperative is to focus on the clinical problem first with careful consideration given to the significant organisational changes which are associated with the introduction of a new or alternative method of health service delivery for remote patients. For telemedicine to be effective it is also important that all sites involved are adequately resourced in terms of staff, equipment, telecommunications, technical support and training. In addition, there are a number of logistical factors which are important when considering the development of a telemedicine service including site selection, clinician empowerment, telemedicine management, technological requirements, user training, telemedicine evaluation, and information sharing through publication.

JCMCTA 2019 ; 30 (1) : 5-11
On Treatment Efficacy of Entecavir in Treatment Naïve Chronic Hepatitis B Patients
Authors: Raha Aloke Kumar , Hoque Mohammad Izazul , Mahmood Abdullah Al , Tarafder Arun Joyti , Chowdhury Dilip , Mahtab Mamun Al
Published: November 2022

Background: Worldwide 250 million people are suffering from Hepatitis B Virus (HBV) infection. Treatment with antiviral drugs improve survival and quality of life by preventing disease progression and Hepatocellular Carcinoma (HCC). Indications for antiviral treatment primarily based on serum HBV DNA, Alanine Aminotransaminase (ALT) and severity of liver disease. Entecavir is one of the potent antiviral drug against hepatitis B virus. This study has been conducted to evaluate the efficacy of entecavir in both Hepatitis Be Antigen (HBeAg) positive and HBeAg negative treatment naïve Bangladeshi patients. Materials and methods: A total 205 patients were enrolled in this study from 2010-2014 in outpatients department of Hepatology in Chattogram Medical College Hospital. All patients got Entecavir 0.5 mg daily and followed at 12 weeks, 24 weeks & 52 weeks of the treatment by ALT, HBsAg, HBe- Ag and HBV DNA. 55 patients lost during follow- up and 150 patients completed 52 weeks treatment and finally evaluated. Results: The mean HBV DNA at baseline was 26.4 x 109 ± 7.4 x 109 copies / ml which was decreased to 2.2 x 106 ± 1.4 x 105 copies/ml at the end of 52 weeks which was statistically significant. At 52 weeks 118 (78%) CHB patient became HBV DNA negative. The mean ALT level before treatment were 96.1 ± 70.9 U/L which were 39.7 ± 11.98 U/L at the end of 52 weeks. At 52 weeks of treatment 78 (71.5%) became HBeAg negative. Conclusion: Entecavir significantly suppress HBV DNA level as well as normalization of aminotransfersae level. It has significant influences on HBeAg negativity in HBeAg positive chronic hepatitis B patients.

JCMCTA 2019 ; 30 (1) : 12-15
Effect of Ramadan on Cardiac Patients Attending Cardiology Department Of Chattogram Medical College Hospital
Authors: Awal Anisul , Tareq Md Nuruddin , Bhattacharjee Biplob , Das Probir Kumar , Shahin Abul Hossain , Uddin Siddique Md Mohammed Saleh , Bhattacharjee Sreepati , Rehan Rezwan
Published: November 2022

Background: During the Ramadan fast, among Muslims due to change in life-style, in terms of obtaining the daily calorie intake via two meals with alteration of medication schedule or reduction in sleep duration, might affect patients with cardiovascular diseases. The aim of this study was to determine the proportion of cardiac patients who fasted and factors associated with breaking fast. Methods and materials: This cross-sectional study was conducted during the month of Ramadan 2018 (17 May to 15 June) in the outdoor and indoor of Cardiology Department of Chattogram Medical College Hospital, Chattogram, Bangladesh. Muslim patient, age above 18 years was included. Pregnant lady lactating mother and Non-Muslims patients were excluded. Data regarding age, sex, comorbid conditions, fasting status and reason for breaking fast if applicable were collected through a case record form and cardio vascular condition was evaluated. Results: Out of 221 patients, 121 (54.8%) were admitted in indoor and 100 (45.2%) patients attended in outdoor. Male to female ratio was equal (Male 103 and female 118) and mean (±SD) age was 53.48±12.22 years. Of those, 76 (73.8%) male and 86 (72.9%) female were fasting. Significantly higher number of female broke fast than male [Male 41 (53.9%) versus female 65 (75.6%). One hundred and twenty fasted patients (78.4%) experienced symptom aggravation and most of them (91.7%) had to break their fast. Aggravating symptoms were chest pain, breathlessness and hypoglycemic attack present respectively in 68.1%, 16.3% and 12.5% patients. Besides symptoms aggravation, other causes of breaking fast were medication in 36 (22.1%) patients and diagnostic procedure in 4 (2.47%) patients. Conclusion: Ramadan fasting had significant effect on female cardiac patients than male. Findings should be investigated with a prospective study.

JCMCTA 2019 ; 30 (1) : 27-30
PERBANDINGAN MODEL GROUP INVESTIGATION DAN METODE EKSPOSITORI TERHADAP HASIL BELAJAR MATEMATIKA SISWA SMP
Authors: Shabira Nadya Rahmah , Susanto Edi , Yensy Nurul Astuty
Published: November 2022

Tujan penelitian untuk mengetahui apakah hasil belajar siswa yang menggunakan model kooperatif tipe group investigation lebih tinggi dari hasil belajar siswa yang menggunakan metode ekspositori pada materi aritmatika kelas VII SMPN 3 Kota Bengkulu. Jenis penelitian yaitu eksperimen semu dengan desain pretest-posttest. Populasi penelitian adalah kelas VII, VII.5 sebagai kelas eksperimen dan VII.4 sebagai kelas kontrol. Instrumen penelitian yaitu instrumen tes berupa soal subjektif. Analisis data menggunakan uji independent sample t-test dan perhitungan N Gain. Hasil penelitian menunjukkan ada perbedaan model pembelajaran group investigation terhadap hasil belajar matematika. Rata-rata nilai posttest kelas eksperimen 46,84 dan kelas kontrol 30,37. Hasil perhitungan menggunakan SPSS dengan tingkat kepercayaan 95% menunjukkan nilai sig. =  dan diperoleh  sehingga  ditolak. Pada perhitungan N Gain didapat rata-rata N Gain pada kelas eksperimen yakni 0,43 dengan kategori sedang dan pada kelas kontrol 0,17 dengan kategori rendah, didapati bahwa angka kenaikan hasil belajar siswa kelas eksperimen lebih tinggi dari angka kenaikan pada kelas kontrol. Hasil penelitian menunjukkan bahwa hasil belajar siswa dengan model group investigation lebih tinggi dari hasil belajar siswa dengan metode ekspositori.
Perancangan Sistem Pemantauan Kondisi Air Pada Kolam Ikan Nila Berbasis Internet Of Thing
Authors: Rizqi Kusuma Pradani Erlillah , Martha Fitriani Indah , Herasmara Ridho
Published: November 2022

Perkembangan teknologi yang sangat pesat memberikan dampak yang baik bagi keberlangsungan kehidupan manusia pada saat ini. Banyaknya perkembangan teknologi yang dapat mempermudahan aktivitas manusia di berbagai bidang seperti dibidang agrikultur, kesehatan, otomatisasi rumah, dan perikanan. Seiring pesatnya perkembangan teknologi nirkabel di bidang perikanan ini memungkinkan untuk menggunakan sistem yang terintegrasi dengan IoT (Internet of Thing). Tujuan umum dari pelakasanaan dari penelitian ini adalah untuk membuat rancangan sebuah alat yang digunakan untuk memantau  kondisi air pada kolam ikan nila dengan menggunakan teknologi IoT. Hal ini dilatarbelakangi oleh kurang efektifnya para peternak ikan nila selama ini pada saat melakukan pengukuran kondisi kolam ikan. Para petani harus datang langsung kekolam ikan mereka dan mengukur pada kolam ikan nila mereka. Kondisi kolam ikan disini adalah suhu dan tingkat keasaman air pada kolam ikan nila. Hal ini dapat dilakukan dengan cara menggunakan sensor suhu air DS18B20 serta sensor pH SEN0161 yang mana digunakan untuk mendeteksi nilai suhu dan nilai tingkat keasaman air pada kolam ikan nila. Hasil simulasi dari penelitian ini nantinya dapat diterapkan menjadi sebuah prototype dan dimanfaatkan para peternak ikan nila agar mempermudah aktifitas peternak ikan dalam upaya mengamati kondisi air dikolam ikan nila. Selain itu, pemanfaatan solar cell sebagai sumber daya pada sistem ini. Hasil dari perancangan ini menggunakan aplikasi bylink pada android dapat menampilkan data dari pembacaan sensor yang dapat diakses oleh peternak ikan nila kapanpun menggunakan internet secara real time. Dengan menerapkan sistem pemantauan kolam ikan nila berbasis Internet of Thing ini dapat mempermudah pekerjaan peternak budidaya ikan nila sehingga peternak budaya ikan nila memiliki lebih banyak waktu luang yang bisa digunakan untuk mengembangkan kolam budidaya ikan nilanya serta usahanya.
Modulation of the Innate and the Adaptive Immune Expression of THP1 Cell Line Following Infection with Leishmania L. Major and L. Donovani Isolates from Sudanese Patients
Authors: Al Dawi Amal F , Ali Sababil S , Ahmed Dalia. M , Mukhtar Maowia M
Published: November 2022

Leishmania, a protozoan parasite, is the causative agent of leishmaniosis. It lives and multiplies within the harsh environment of macrophages. Infection of macrophages by the intracellular protozoan Leishman leads to downregulation of a number of macrophage innate host defense mechanisms, thereby allowing parasite survival and replication. In order to investigate how intracellular parasite manipulates the host cell environment, we undertook a quantitative study of human monocyte-derived macrophages (THP-1) following infection with L. donovani and L. major. In this study we aimed to measure the proliferation rate of human (THP1) macrophage cell line following infection with cutaneous and visceral leishmania isolates. We used sysmex to measure the proliferation rate of human (THP1) cells infected with cutaneous and visceral leishmania isolates after invitro infection of human (THP1) Macrophage cell line by leishmania isolates. We detected L. major significantly increased the proliferation of infected THP1 cell line compared with L. donvani. Our findings indicate that the infection of host cells human macrophage cell lines by L. major stimulates the replication of the cell as a mechanism to enhance the replication of the parasites.
Cardiotoxicity: Role of Sacubitril-Valsartan in Heart Failure with Reduced Ejection Fraction and Cancer with Hepatic Metastasis
Authors: Marisa Brochado , Afonso Nogueira Marta , Fernanda Ferreira , Gonçalo Proença
Published: November 2022

The aim of this report is to describe the impact of pharmacological treatment with sacubitril/valsartan in a patient with stage IV colon cancer. We describe the case of a 69-year-old woman with heart failure with reduced ejection fraction and the diagnosis of colon cancer with hepatic metastasis. By the time of the diagnosis, the patient was already under titration of sacubitril/valsartan with tolerability up to the maximum dose. Due to the optimized heart failure treatment, the patient underwent surgery and initiated chemotherapy without any cardiovascular complications, demonstrating that sacubitril/valsartan was safe in this complex situation.
ANALISIS PRODUKTIVITAS PENGGILINGAN PADI MENGGUNAKAN METODE MULTI FACTOR PRODUCTIVITY MEASUREMENT MODEL (MFPMM) (STUDI KASUS: UD. SEKAR JAYA)
Authors: Hermawan Dwi Wijaya  , Sunday A. T. Noya  , Purnomo
Published: November 2022

UD. Sekar Jaya merupakan salah satu jenis usaha yang memproduksi beras (penggilingan padi). UD. Sekar Jaya sudah berdiri sejak 1985 dan bertempat di Kecamatan Bangorejo, Banyuwangi, Jawa Timur. Sumber bahan baku padi dibeli dari beberapa supplier, dan juga dari petani secara langsung. Pada kegiatan produksinya, usaha ini menggunakan mesin giling, mesin pengering padi (dryer), dan mesin kiby. Pengukuran produktivitas belum pernah dilakukan pada proses produksi, sehingga diperlukan pengukuran produktivitas yang mencakup material, tenaga kerja, dan energi. Pengukuran produktivitas hanya dilakukan pada bagian produksi beras obor premium saja. Metode yang digunakan untuk mengukur tingkat produktivitas pada penggilingan padi atau produksi beras yaitu metode Multi Factor Productivity Measurement Model (MFPMM). Hasil perhitungan metode MFPMM adalah produktivitas, pemulihan harga, dan profitabilitas dari UD. Sekar Jaya. Setelah dilakukan analisis dari hasil perhitungan, diketahui perubahan produktivitas UD. Sekar Jaya dari faktor material, tenaga kerja, energi, dan total mengalami penurunan. Oleh sebab itu dilakukan implementasi perbaikan seperti mencari padi yang berkualitas baik, peningkatan tara jika kualitas padi jelek, menempatkan pekerja untuk memeriksa padi, dan menerapkan sistem gaji borongan. Perubahan indeks produktivitas setelah implementasi dari material, tenaga kerja giling dan kiby, tenaga kerja limbah, energi dan total input sebesar (1,0087), (1,0828), (1,0828), (1,0352), dan (1,099). Peningkatan tersebut menandakan bahwa implementasi yang dilakukan berhasil.
Tim Editor dan Daftar Isi
Authors: Tim Editor Jurnal SAKTI
Published: November 2022

Tim Editor Jurnal SAKTI dan Daftar Isi untuk Volume 2 Nomer 2 Juni 2022
Asset Inventory System of Employee Cooperative’s Pusri Palembang Inc.
Authors: Khudri Akhmad , Saputra Rajib Oki
Published: November 2022

Employee cooperative has been widely existed in every institution in Indonesia, both at governement and non-government. This research aims at facilitating the office employees of the Pusri Employee Cooperative to manage the assets owned. To support this convenience, the author proposes an asset inventory system using VB.Net 2008 and MySQL database. The proposed system can be used to manage asset data in the form of asset data input, asset search, asset grouping, deletion, sales and asset reports owned. With the creation of an asset inventory system, the performance of office employees will be faster and more efficient and ensure the security of asset data. In this study the author uses the Waterfall research method including several stages i.e., requirements analysis, system design, program code generation, testing and maintenance. The method of data collection is done through interviews and direct observation to the object of research. The results of the research are expected to be useful for all office employees of the Pusri Palembang Employee Cooperative in managing data on assets owned by the office.
Interleukin-23 in Psoriasis: Integrating New Therapies in the Current Treatment Landscape
Authors: Grills Jane
Published: November 2022

Prof Reich welcomed delegates to the satellite symposium and explained that the aims of the meeting were to introduce the clinical role of targeted interleukin (IL)-23 therapies in psoriasis, show why IL-23 therapy is effective against psoriasis, show how it works in patients by illustrating emerging clinical trial data, and, finally, describe how the IL-23 inhibitors can be used to address unmet clinical needs in patients with psoriasis. Dr Blauvelt started the meeting by providing an update on the current understanding of the immunology of cytokine pathways in psoriasis. Prof Reich then gave an overview of the clinical value of IL-23 inhibitors as novel targeted treatments for psoriasis, summarising data from pivotal clinical trials that have been carried out to support the introduction of these treatments into the clinical armamentarium. Finally, Prof Girolomoni reviewed the indications for biologic therapies and discussed how IL-23 inhibitors can be integrated into the current therapeutic environment. The satellite symposium concluded with a lively question and answer session.
Lingual Pustular Psoriasis and Acrodermatitis Continua of Hallopeau Successfully Treated with Adalimumab: A Rare Case Report and Review of Oral Psoriasis
Authors: Touyz Sarah J.J. , Pratt Melanie
Published: November 2022

Psoriasis is a common skin disease with various cutaneous manifestations and is classified into two clinical groups: non-pustular and pustular. Pustular psoriasis is less common than non-pustular forms of psoriasis and is particularly resistant to treatment. Studies of the rarer variants of acrodermatitis continua of Hallopeau and pustular psoriasis of the tongue remain scant. The subtypes of psoriasis can present all over the body, including in uncommon locations, such as the oral cavity; however, there are limited presentations and data regarding oral involvement in psoriasis and its subsequent management. Although cases involving oral psoriasis are rare, with <100 publications in the literature, and generally asymptomatic, recent studies have suggested that it is more prevalent than once thought. In contrast, presentation and subsequent management of lingual pustular psoriasis have not been reported. Presented and discussed in this review is a rare case of symptomatic, painful lingual pustular psoriasis and acrodermatitis continua of Hallopeau with complete remission after the use of adalimumab, followed by a thorough review of the histopathology, diagnosis, and clinical management of oral psoriasis. The use of biologics for conditions involving the oral mucosa, particularly in the setting of cutaneous psoriasis, is a novel concept with potential application in the fields of dermatology, oral medicine, and rheumatology.
Hidradenitis Suppurativa: A Retrospective Review of 13 Patients and Literature Summary
Authors: Persaud Reneeka , Elliott James A. , Goodman Laurie , Somayaji Ranjani , Lim Morgan , Sibbald R. Gary
Published: November 2022

Hidradenitis suppurativa (HS) is an inflammatory skin condition of the follicular pilosebaceous unit that primarily affects flexural areas where apocrine glands are found. This disorder can present as either an acute or chronic disease, with a single subcutaneous nodule or clusters of painful abscesses with purulent drainage in one or more of the following sites: axilla, groin, genital, perianal (more common in males), and under the breasts (more common in females). Over time patients form sinus tracts, fibrosis, and scarring. The onset usually occurs in the early 20s, after puberty. HS can be present for years without being diagnosed and is associated with a diminished quality of life, high morbidity, and substantial healthcare costs. Global HS prevalence is estimated at 1%.

This article reviews a retrospective cohort study of 13 patients assessed by an interprofessional wound care team and discusses relevant literature. Accuracy of referral diagnosis was the primary outcome. Secondary outcomes included demographics and quality of life. In total, 10 patients were female (77%) and the mean age was 33 years. Fewer than half (n=6, 46%) had an accurate diagnosis of HS prior to team assessment. Of these patients, the mean time before a correct diagnosis was 4.2 years. Untreated bacterial damage was diagnosed in the majority of patients (n=9, 69%). There was substantial improvement in pain levels and quality of life in approximately half of the cases. Over time, patients became more actively involved in their care. Our findings show HS diagnosis and management is optimised with an interprofessional team approach.
Quality of Care: The Challenges, The Solutions
Authors: Siak Steven
Published: November 2022

Psoriatic arthritis (PsA) and hidradenitis suppurativa (HS) are both immune-mediated diseases with common cellular and cytokine pathways involved in their pathogenesis.1 Both are characterised by chronic and systemic inflammation and both involve elevated levels of the cytokines tumour necrosis factor-α (TNF-α), interleukin-17, and interleukin-23.1-5 PsA and HS are associated with substantial unmet needs and are sub-optimally managed. This educational session discussed ways to improve the quality of care and patient outcomes in PsA and HS.

Dr Kim Papp opened the symposium with an overview of the current unmet needs in PsA and HS and the key barriers to improving the management of both diseases. Prof Hilary Thomas discussed the Quantum initiative and how it could assist dermatologists in the treatment of PsA and HS. Dr Papp and Prof Christos C. Zouboulis then discussed the challenges of achieving optimal management in PsA and HS, as well as the solutions.
Reconstructive Options for Cutaneous Defects of the Nose: A Review
Authors: Jayarajan Rajshree
Published: November 2022

Background: The face is the most common site affected by skin cancer in the body and of the facial skin it is the nose that bears the brunt of the attack.1,2 Cancer resection results in the loss of a significant amount of tissue requiring replacement with either grafts or flaps in many cases. The expectation in nasal reconstruction, whether minor or major, is the restoration of symmetry, contour, colour match, and an overall pleasing result.

Objective: To review the various reconstructive options available for cutaneous defects of the nose following skin cancer resection and to describe outcomes associated with each.

Methods: A literature review was performed using PubMed, books, and websites. These were compiled to create a list of available options for the reconstruction of cutaneous defects on anatomical areas of the nose.

Results: Nasal reconstructive techniques have been evolving over centuries. With our advanced knowledge regarding blood supply and lessons learned from experiences, we have achieved a standard that offers excellent aesthetic results. The benefits and drawbacks of the common flaps are enunciated to provide a basis for decision making as to the best method to yield the optimum result in the reconstruction of cutaneous defects of the nose following resection of skin cancers.
A Review of the European Society for Photodynamic Therapy (Euro-PDT) Annual Congress 2018
Authors: Braathen  , Morton  , Szeimies
Published: November 2022

This article reviews new data presented at the recent European Society for Photodynamic Therapy (Euro-PDT) Annual Congress 2018. The role of topical photodynamic therapy (PDT) in the treatment of actinic keratoses (AK), among other therapies, was reviewed, along with updates on rising incidence of nonmelanoma skin cancer (NMSC), awareness of skin cancer risk in outdoor workers, and the potential of PDT as a treatment for prevention of AK and NMSC. A novel scoring method for AK and potential biomarkers for skin cancer, as well as those predictive of PDT response, were presented. Several studies highlighted real-world use of daylight (DL)-PDT across Europe and of its use in novel indications, including acral AK, application following organ transplant, and the option for home-based DL-PDT. New data on PDT combined with other therapies, as well as using novel light sources, will broaden the appeal of PDT to patients and practitioners. Optimisation of PDT using pretreatments and improving the tolerability of the treatment will boost efficacy and patient preference for this therapy. Evidence for off-label use of PDT presented at the congress included antimicrobial and aesthetic indications.
Innovation That Drives Your Dermatological Future
Authors: von Riedemann Sarah
Published: November 2022

The main objectives of this symposium were to review the importance of topical therapies in the treatment of psoriasis and the unmet clinical and patient quality of life (QoL) needs that still exist, to discuss the innovation seen with reformulations of existing active pharmaceutical ingredients (API), and to align changes in future dermatology practice with these topical treatment innovations. Mr Fernández introduced the topic of ‘looking to the future’, with a wide-ranging, big-picture view of the changing face of medical practice and the increasing role of technology, including specific examples of how these trends will affect dermatology practice. Prof Surber built on the theme of innovation to discuss how novel products and approaches can be pursued in dermatology, particularly in the area of topical psoriasis treatments. Prof Surber’s presentation and the subsequent talk by Dr Bewley described how innovations can translate into improved patient outcomes in key areas, including psoriasis control, itching, sleep, and overall health-related QoL. Prof Bonnekoh tied the various threads of the symposium together by showing how the new technological and pharmacological options could help clinicians evolve their overall approach to long-term topical management of psoriasis, moving from a more reactive mindset to safe and effective proactive control. Finally, the audience was given the opportunity to ask questions in a brief panel discussion.
Impact of conservation partnership on improving community welfare in the Gunung Masigit Kareumbi Hunting Park, West Java, Indonesia
Authors: Munandar Aris , Priatna Dolly , Retnowati Rita
Published: November 2022

In conservation areas throughout Indonesia, there are at least 1.8 million hectares of open land in the form of damaged or degraded ecosystems following encroachment on conservation areas by local communities. Addressing this, the government of Indonesia has introduced a conservation partnership policy issued in 2018, namely the Director General of KSDAE Regulation No. P.6/KSDAE/SET/Kum.1/6/2018 concerning Technical Guidelines for Conservation Partnerships in Nature Reserves and Nature Conservation Areas. The objective of this study was to identify and analyze the impact of conservation partnerships on improving the welfare of the community in the Gunung Masigit Kareumbi Hunting Park (GMKHP). The research was conducted within the GMKHP area, with the samples taken from the community of Forest Farmer Groups (KTH) in the villages of Pelita Asih, Jaya Mekar, Sunda Mekar, Cikadu, Sukajaya, and Kaduwulung. The approach used in this study is qualitative. Data were collected by questionnaire survey, interviews, observations, and documentation in the field. Based on the results of the study, it is known that the production of pine resin tapping carried out by KTH members is as much as 29,033 kg/month or an average of 323 kg/person per month.  This activity has an impact on increasing the income of KTH members by 170%, i.e. from their initial average income of Rp. 853,778 per month to become Rp. 2,307,278/month for each member.  Additionally, there are also contributing funds to the neighborhood and social welfare coordinated by cooperatives, such as assistance for the poor and orphans, village treasury income, BUMDes (Village Enterprise) capital, wages for reading Qoran teachers, mosque maintenance, etc.
Seawater quality and diversity of phytoplankton species in the waters of the North Coast of Jakarta
Authors: Hamdani Moh. , Kusumahadi Khoe Susanto , Setia Tatang Mitra
Published: November 2022

The North Coast of Jakarta is a strategic area to support the economy of the DKI Jakarta Province and as a place to live for organisms, one of which is phytoplankton. Phytoplankton is a primary producer in aquatic ecosystems that have an essential role in maintaining aquatic ecosystems and as an indicator of water quality. This study aims to determine the quality of seawater (turbidity, TSS, BOD, Phosphate, and Nitrate) and the diversity of species (H') of phytoplankton in the waters of the North Coast of Jakarta around the reclamation islands C and D from 2006 to 2021. Types of data used in this study is secondary data from Environmental Impact Analysis (ANDAL) documents and reports on the implementation of the Environmental Management Plan and Environmental Monitoring Plan for Reclamation and Development on Islands C and D. Concentrations of turbidity, TSS, BOD, phosphate, and nitrate in coastal waters North of Jakarta around the reclamation islands C and D are fluctuation and several sampling times exceed the quality standard. The species diversity index (H') of phytoplankton in the coastal waters of North Jakarta around the reclamation islands C and D is dominantly included in the criteria for community stability in stable conditions (H 3). Based on the partial correlation test, phosphate with the diversity of phytoplankton species in the waters of the North Coast of Jakarta around reclamation island C and D had a significant relationship (P 0.05).
The Effect of Wind Speed on the Efficiency of Wind Turbines
Authors: Waghani Krish
Published: November 2022

This experiment’s aim is to investigate the impact that different wind speeds have on a wind turbine’s efficiency. This will be done by making observations on the maximum theoretical power capacity of the wind turbine, and the actual power that it generates. It was predicted that higher wind speeds would corroborate with lower efficiencies. A wind speed of 15.8 m/s had an efficiency of 3.22%, while a wind speed of 3.3 had an efficiency of 40.58%. However, it was concluded that there is a “sweet spot”, wherein the efficiency of the wind turbine is optimum. Any increase or decrease of wind speed in this region would cause the efficiency to reduce.
Korozyon Etkisine Maruz Kalmış Betonarme Kirişlerin Doğrusal Olmayan Analizi
Authors: Subaşı Rojda Orman , Subaşı İlker , Çağlar Naci , Dok Gökhan , Öztürk Hakan
Published: November 2022

Geçmişte ve günümüzde yapı güvenliğini etkileyen en önemli unsurlardan biri korozyon olayıdır. Meydana gelen korozyon sonrası betonda dökülme ve çatlamalar, donatı kesit alanında ve beton ile donatı arasındaki bağ kuvvetlerinde azalma meydana gelmektedir. Bu durum betonarme yapı elemanlarının süneklik, rijitlik ve dayanım gibi önemli özelliklerini olumsuz yönde etkilemektedir. Yapılan çalışma kapsamında korozyon etkisine maruz kalmış betonarme kirişlerin eğilme yükü etkisi altındaki davranışını temsil edebilen doğrusal olmayan bir sonlu eleman modeli (SEM) geliştirilmiştir. Bu amaçla, literatürden seçilen farklı seviyelerde korozyon etkisine maruz betonarme kirişler için sonlu eleman modeli oluşturulmuştur. Söz konusu betonarme kirişlerin eğilme yükü etkisi altındaki davranışını simüle etmek için ABAQUS paket programı kullanılmıştır. Elde edilen nümerik sonuçların literatürden seçilen deneysel çalışma sonuçlarını başarılı bir şekilde yansıttığı görülmüştür. Simülasyon çalışmasına ek olarak değişen korozyon ve donatı oranının betonarme kirişlerin eğilme davranışı üzerindeki etkisini araştırmak için parametrik bir çalışma yapılmıştır. Parametrik çalışma sonuçları korozyon seviyesine ve donatı oranına bağlı olarak karşılaştırmalı bir şekilde incelenmiştir.
Python Programlama Dili ile Betonarme Kirişlerin Şekil Değiştirme Sınırlarının İrdelenmesi
Authors: Demir Aydın
Published: November 2022

Bu çalışmada betonarme binalarda kesit bazında şekildeğiştirme ve plastik dönme sınırlarının uygulayıcı mühendisler tarafında gerçekçi olarak anlaşılması ve tespit edilebilmesine katkı sağlanarak, deprem afetiyle oluşabilecek can ve mal kabı riskinin azaltılması amaçlanmıştır. Çalışmada, öncelikle TBDY-2019’da şekildeğiştirme sınırları için yeni getirilen hususlar açıklanmış ve DBYBHY-2007’dan farkları gösterilmiştir. Daha sonra, gerçekleştirilen sayısal çalışmada, yönetmeliklerde betonarme kirişlerin tasarımı için verilen sınırlar dikkate alınarak farklı geometri, malzeme ve donatı özellikleri olan betonarme kiriş elemanları tasarlanmıştır. Türkiye’deki mevcut yapı stokunda yönetmeliklerde belirtilen kriterlere uyman elemanların davranışlarının incelenmesi için malzeme dayanımı yetersiz ve enine ve boyuna donatı oranları düşük betonarme kirişler de eleman matrisine eklenmiştir. Tüm elemanların şekildeğiştirme ve plastik dönme sınırları ilgili yönetmeliklere göre hesaplanmıştır. Bu hesaplarda kullanılmak amacıyla Python programlama dilinde bir bilgisayar kodu da yazılmıştır. Çalışmadan elde edilen sonuçlar; enine ve boyuna donatı oranı, beton basınç dayanımı açısından parametrik olarak incelenerek betonarme kirişlerin şekildeğiştirme ve plastik dönme sınırlarına bu parametrelerinin etkileri irdelenmiştir.
EDUKASI MENGENAI INFORMASI BOHONG (HOAKS) DI KALANGAN GURU BERBASIS LITERASI
Authors: Pratiwi Brillianing , Mohammad Adning
Published: November 2022

The purpose of this study was to analyze the educational needs of teachers regarding hoaxes and provide preventive measures to prevent hoaxes among teachers. This study uses a qualitative method with a case study approach. The results of this study indicate the importance of education programs regarding hoax information among teachers so that teachers do not immediately conclude the contents of the news without reading in detail about the contents of the news. In addition, teachers have more literacy awareness in seeking clarification of the truth about a hoax, reducing the rapid spread of hoaxes, and being able to spread digital literacy skills to students. Teachers as professionals have a strategic role to realize the vision of learning implementation. The development of science and technology brings logical consequences to the orientation of the development of teacher professionalism. The conclusion of this study is that a teacher needs to have digital literacy skills so that they are able to disseminate correct information.
All-Russian Scientific and Practical Conference "Development of Russia's Scientific Potential"
Authors: Koroleva Natalya
Published: November 2022

On September 15–16, 2022 RIEPP hosted the All-Russian Scientific and Practical Conference "Development of Russia's Scientific Potential" aimed at addressing topical issues and decision-making in the develop­ment of international cooperation in science and technology in Russia in terms of global challenges, intellectual property management in science and technology, improving government support of scientific and tech­nological activities, and the functioning of scientific and technological infrastructure as the basis for the development of critical technologies in the Russian Federation; Improving the organization of record keep­ing and archiving in the Ministry of Education and Science of the Rus­sian Federation and its subordinate organizations. The conference was moderated by the director of RIEPP I. E. Ilina. Representatives of federal and regional state authorities, scientific and educational organizations, regional funds for the support of scientific and scientific-technical activ­ity, leading specialists and experts on intellectual property management and technology transfer, employees of RAS, representatives of leading CKPs and UNUs were participants of the round tables.
Comparative proteomics analysis of Schistosoma japonicum developed in different Oncomelania snails as intermediate hosts
Authors: Liu Gongzhen , Miao Feng , Wang Yongbin , Kou Jingxuan , Yang Kun , Li Wei , Xiong Chunrong , Zhang Fengjian , Wang Xinyao , Yan Haoyun , Wei Changyin , Zhao Changlei , Yan Ge
Published: November 2022

Schistosomiasis is a tropical parasitic disease that seriously endangers humans and animals. In this study, two Oncomelania snails, Oncomelania hupensis (O. hupensis) and Oncomelania weishan (O. weishan), were infected with Schistosoma japonicum (S. japonicum) cercariae during the early period, and ICR mice were subsequently infected with two kinds of miracidia that developed in male and female adult worms. In this study, isobaric tags for relative and absolute quantification (iTRAQ) were used to identify four channels: 113, 115, 117, and 119. A total of 2364 adult schistosome proteins were identified, and 1901 proteins were quantitative. Our results revealed 68 differentially expressed proteins (DEPs) in female adult worms, including 24 upregulated proteins and 44 downregulated proteins, and 55 DEPs in male adult worms, including 25 upregulated proteins and 30 downregulated proteins. LC-MS/MS and bioinformatics analysis indicated that these DEPs are mainly concentrated in cellular composition, molecular function, biological function and catabolism pathways. In summary, this proteomics analysis of adult schistosomes that hatched in two intermediate hosts helps to improve our understanding of the growth and developmental mechanisms of S. japonicum.