bluuebunny/crossref_metadata_2025 huggingface dataset:
The State of American Education during the Covid-19 Pandemic: Survey of American Public, Private, and Charter School Teachers
Authors: Song Holim , Owens Emiel W.
Published: June 2021

The purpose of the present study was to examine how teachers and students are adjusting to the new online platform, the frequency and significance of connectivity problems and how teachers believe their students’ education quality is. An electronic link to a Qualtrics survey was sent to participants and a snowball sampling procedure (Handcock & Gile, 2011) was used. The online survey was open for 4 weeks and a total of 165 teachers representing 22 states across the U.S. In general, a large percent of students across the country do not have stable or any internet services in their home. Furthermore, even for those that have internet access, connectivity issues caused problems for the entire class. New teachers in their first five years are less likely to offer alternatives when internet was not available and more likely changed their curriculum due to internet access issues.
Hiperamonemia como causa de diálisis no renal
Authors: Wancjer Nelds Benjamín , Molano Triviño Alejandra , Yucuma Gutiérrez Samuel , Martínez Montalvo Carlos Mauricio
Published: June 2021

La hiperamonemia es una condición frecuente en pacientes cirróticos y en el contexto de una causa no cirrótica se relaciona con aumento en la producción de amonio o alteración en su eliminación. La presentación clínica de esta condición es inespecífica: va desde alteración del comportamiento hasta estado de coma, siendo una de las causas de diálisis no renal por determinados valores o refractariedad a manejo médico. Se presenta el caso de una mujer de 35 años, quien ingresó al servicio de urgencias con alteración del estado de conciencia, niveles de amonio elevados y masa hipervascular en hígado. Los estudios de aminoácidos limitantes del ciclo de la urea y ácido orótico urinario fueron normales y la biopsia de la lesión hepática reportó carcinoma hepático fibrolamelar, al cual se atribuyó la presencia de shunt portosistémico que causaba la hiperamonemia. Se indicó diálisis por persistencia de elevaciones de amonio y poca respuesta al tratamiento médico. Dada la evolución de la paciente, fue necesario reiniciar la terapia reemplazo renal por reaparición de estado encefalopático al suspender la misma. Esta terapia se mantuvo hasta el trasplante hepático que se realizó como tratamiento del carcinoma, con posterior estabilización de niveles de amonio y suspensión de la diálisis.
Nefropatía por inmunoglobulina A en pediatría, desenlaces clínicos con diferentes esquemas de manejo
Authors: Forero-Delgadillo Jessica , Torres-Canchala Laura , Galvis-Blanco Laura , Lasso Ruben , Aguirre Jesus , Duque Natalia , Jimenez Carlos , Arrunategui Ana María , Londoño Hernando , Restrepo Jaime Manuel
Published: June 2021

Introducción:la nefropatía por inmunoglobulina A (NIgA) es la enfermedad glomerular más común en el mundo. En Colombia, el 11-22 % de las glomerulonefritis primarias en niños corresponden a NIgA y de estos casos, el 30 % progresa a enfermedad renal terminal.
Objetivo: describir las características paraclínicas e histopatológicas de la NIgA, así como los resultados clínicos según tres tipos de tratamiento en pacientes pediátricos con esta enfermedad atendidos en un hospital de alta complejidad del suroccidente colombiano.
Materiales y métodos: estudio retrospectivo realizado en pacientes pediátricos de entre 1 mes y 18 años de edad con diagnóstico de NIgA. Las variables categóricas se presentaron como proporciones y las continuas con medianas y rango intercuartílico. Se usó la prueba de Fisher para comparar los tres esquemas de tratamiento.
Resultados:se incluyeron 58 pacientes pediátricos atendidos entre 1996 y 2013. La media de edad al inicio de síntomas fue 7,5±4,2 años y al momento de la biopsia renal, 10±3,8 años. El 77,6 % de los pacientes presentó hematuria microscópica y el 27,6 %, macroscópica. Además, el Histológicamente, el 10 % se clasificó como grado I, el 62 % como grado II, el 21 % como grado III y el 7 % como grado IV. Tres pacientes requirieron diálisis 81 % tuvo proteinuria, siendo severa el 29 %. y dos, trasplante renal. Los esquemas terapéuticos evaluados fueron: solo prednisona (n=20, 34,5 %), prednisona y mofetil micofenolato (MMF) (n=13, 22,4 %) y sin prednisona ni MMF (n=25, 43,1 %). La diferencia en la presencia de hematuria entre los grupos fue significativa (p>0,001), siendo más frecuente en el grupo sin prednisona ni MMF (68 %). No hubo diferencia entre los grupos de proteinuria, hipertensión arterial y valor de creatinina. La mediana de años entre la biopsia renal y el ultimo control fue de 4 años (RIC 1-7). La supervivencia de la función renal fue del 89,1 % a los 5 años.
Conclusión:la NIgA amerita reconocimiento temprano y seguimiento estricto, ya que puede tener desenlaces ominosos como enfermedad renal crónica.
Efectividad y seguridad del uso de alfa-cetoanálogos en el manejo de la enfermedad renal crónica avanzada: recomendaciones para la práctica clínica
Authors: Ramírez Marmolejo Roberto , Aroca Gustavo , González González Camilo Alberto , Pertuz Adolfo , Collazos Rozo Juan Manuel , Galeano Javier A. , Mercado Juri Álvaro
Published: June 2021

Introducción:la dieta con restricción de proteínas parece tener un papel importante en la progresión de la enfermedad renal crónica (ERC) y la aparición anticipada de síntomas urémicos, además la suplementación de aminoácidos esenciales ofrece aparente seguridad para lograr restricciones agresivas de proteínas.
Objetivo: realizar una revisión de la literatura para establecer las recomendaciones de uso práctico sobre la dieta con restricción de proteínas en la ERC avanzada.
Materiales y métodos:se realizó una búsqueda estructurada rápida de la literatura en la que se incluyeron revisiones sistemáticas y metaanálisis, de los cuales se extrajeron las respuestas de las preguntas con estructura PICOT diseñadas a priori. Los resultados fueron sometidos a consenso para generar recomendaciones prácticas.
Resultados:se incluyeron 6 revisiones sistemáticas de la literatura con una evaluación de calidad moderada. Según los hallazgos, una dieta muy baja en proteínas con suplementación de alfacetoanálogos beneficia a los pacientes que ingresan a diálisis o son sometidos a trasplante renal, además reduce la progresión de la enfermedad. No obstante, se requiere de ensayos clínicos con mejor calidad que consideren aspectos como la calidad de vida.
Conclusión:aunque la evidencia es de baja calidad, se establece que la dieta muy baja en proteínas y suplementada con alfa-cetoanálogos en pacientes adecuadamente seleccionados reduce el deterioro de la tasa de filtración glomerular y parece reducir el ingreso a diálisis. Por tanto, se recomienda hacer un seguimiento estricto y periódico en el que se vigilen las medidas antropométricas y el perfil de riesgo de desnutrición.
Caracterización clínica y metabólica de pacientes con diagnóstico de urolitiasis en una clínica de cuarto nivel en la ciudad de Barranquilla, Colombia
Authors: Licona Vera Erick Ricardo , Perez Padilla Rafael Vicente , Ramos Clason Enrique , Torrens Soto Jeison Enrique , Abuabara Franco Emilio , Caballero Rodriguez Luis Ricardo , Cerda Salcedo Jose Eduardo , Sierra Macias Yeraldin , Morales Jurado Luis Fernando , Caballero Rodriguez Carlos
Published: June 2021

Introducción:la urolitiasis es una enfermedad frecuente de la cual en Colombia se han publicado estudios previos; sin embargo, estos no comparan las características sociodemográficas y clínicas de los pacientes con las comorbilidades y los factores predisponentes de litiasis como hiperuricemia, hipertensión arterial (HTA), obesidad y enfermedad renal crónica (ERC).
Objetivo: caracterizar clínica y metabólicamente los pacientes con diagnóstico de urolitiasis atendidos en una clínica de cuarto nivel de Barranquilla, Colombia, en el año 2019.
Materiales y métodos: se realizó un estudio observacional, descriptivo y transversal en 49 pacientes con base en el estudio de fichas clínicas.
Resultados:el 53,1 % de los participantes eran hombres y las medianas de edad y de índice de masa corporal (IMC) fueron 58 años y 26,4 kg/m2, respectivamente. Algunas de las comorbilidades identificadas fueron, en orden de frecuencia, HTA (69,4 %), ERC (36,7 %), infección de vías urinarias recurrente (24,5 %), hiperuricemia (44,9 %), hipercalcemia (16,3 %) e hiperfosfatemia (12,2 %). Los tipos de cristal encontrados fueron oxalato (20,4 %), urato (12,2 %), mezcla de oxalato y urato (4,1 %), fosfato (4,1 %), hipercalciuria e hiperoxaluria (38,8 %), hiperuricosuria e hipocalciuria (18,4 %) y hipofosfaturia o hipofosfaturia (4,1 %). Asimismo, la hiperuricemia se asoció a edad (p=0,028), ERC (p=0,026), medicamentos antihipertensivos (p=0,022), posición del cálculo en cáliz renal (p=0,012), hiperparatiroidismo (p=0,007), depuración de creatinina (p=0,046) e hipercalciuria (p=0,049). El IMC ?  30 se asoció con ERC estadio 5 (p=0,025), diálisis (p=0,025) e hiperoxaluria (p=0,021).
Conclusión:en la población analizada se evidenció una frecuencia significativa de ERC, hiperuricemia, obesidad e HTA.
Explorando el poder de los abordajes transcriptómicos para identificar biomarcadores asociados a daño renal en pacientes con lupus eritematoso sistémico
Authors: Arrieta Bravo Valentina , Rangel Gómez Tiffany , Pacheco Lisandro
Published: June 2021

El lupus eritematoso sistémico (LES) es una enfermedad compleja y altamente heterogénea que afecta múltiples órganos, incluyendo articulaciones, corazón, sistema hematopoyético, sistema nervioso y riñón, siendo este último el de peor pronóstico y el que conlleva a nefritis lúpica (NL). Aunque la etiopatogénesis del LES aún no se conoce con claridad, se cree que la susceptibilidad genética y las modificaciones epigenéticas aberrantes favorecen su desenlace. Para establecer una terapia precisa es necesario evaluar de manera eficiente y objetiva el compromiso de órganos y la actividad de la enfermedad, lo cual es muy difícil por las pocas pruebas de laboratorio clínico disponibles en la actualidad. En las últimas décadas la búsqueda de nuevos biomarcadores de LES ha sido una tendencia y se han identificado varios promisorios a nivel de genómica, metabolómica, proteómica y transcriptómica. En esta revisión se resume el estado del arte relacionado con estudios transcriptómicos que han identificado diversos transcritos potencialmente útiles como biomarcadores del LES y la NL.
Lesión renal aguda en la mujer embarazada
Authors: Monterrosa Robles Maria , Rico Fontalvo Jorge , Daza Arnedo Rodrigo , Pérez Olivo José , Cardona Blanco María , Pájaro Galvis Nehomar Eduardo , Pérez Calvo Christian , Caparroso Ramos Lacides , Leal Martínez Victor , Abuabara Franco Emilio , Uparella Gulfo Isabella , Mendoza García María , Correa Guerrero Jose
Published: June 2021

Aunque en la actualidad la lesión renal aguda en mujeres embarazadas es una complicación poco común, esta se correlaciona con peores desenlaces maternos y fetales. Sus causas son múltiples y varían según el trimestre de presentación. Los cambios fisiológicos renales durante el embarazo hacen que los criterios diagnósticos de lesión renal aguda en la población general no sean fácilmente extrapolables a las pacientes obstétricas, por lo que la sospecha temprana y eltratamiento oportuno son fundamentales para evitar la progresión del daño renal y sus complicaciones sistémicas asociadas, incluidas las metabólicas, urémicas e hidroelectrolíticas.
Desafios da Administração Pública: a gestão de escolas públicas em Teixeira de Freitas, Bahia, Brasil
Authors: Gomes Aline Fonseca , Costa Passinhas David Manuel , Andrade Santos Eduarda , Santiago Carneiro Etiene , Silva de Jesus Jackeline , Freitas Figueiredo Nathalya
Published: June 2021

Nesta pesquisa sobre gestão escolar que objetivou de forma geral identificar os principais problemas enfrentados pelos gestores das escolas públicas municipais de Teixeira de Freitas – BA, Brasil. Foi conduzida pesquisa com abordagem quali-quantitativa e descritiva com aplicação de instrumento de coleta de dados (questionário semi estruturado) junto a oito gestores de Instituições de Ensino públicas do município de Teixeira de Freitas. Por meio da pesquisa foi possível descrever alguns fatores negativos nas esferas da gestão escolar pedagógica, financeira e administrativa, além dos relatos sobre as dificuldades enfrentadas pelos gestores. Além do mais, no requisito pedagógico, foi relatado pelos entrevistados a falta do apoio e acompanhamento dos pais na vida escolar dos filhos. Como resultados da pesquisa foram identificados os problemas principais, tais como: a falta de acompanhamento, dificuldades financeiras, falta de infraestrutura, falta de ferramentas de gestão. Além disso, por desafios e perspectivas, constatou-se que a gestão escolar é uma ferramenta importante da educação e que a mesma engloba aspectos referentes à parte interna da instituição que pressupõe o planejamento e o controle.
TROMBOSE RELACIONADA AO USO DE ANTICONCEPCIONAL: REVISÃO INTEGRATIVA
Authors: Da Cruz Leite Rafaela , Gomes Liane Oliveira Souza
Published: June 2021

Objetivo: Analisar na literatura científica a relação da ocorrência de trombose associado, ao uso do anticoncepcional na Biblioteca Virtual em Saúde (BVS) no período de 2005 a 2015. Material e Métodos: Trata-se de uma revisão sistemática, realizada na Biblioteca Virtual em Saúde (BVS), a partir da leitura de artigos pesquisados no período de agosto de 2015 à novembro de 2016. Foram utilizados os seguintes descritores: trombose, anticoncepcional, trombose and anticoncepcional utilizando o operador boleano “and”. A análise foi realizada baseado na análise de conteúdo temática. Resultados: Constatou-se que as mulheres que fazem uso do anticoncepcional oral têm alto risco para desencadear a trombose, devido aos efeitos colaterais do método, dentre outros motivos. Percebe-se que a faixa etária mais acometida são as mulheres de 20,8 a 57,4 anos de idade. Conclusão: Enfim, faz-se necessário à implementação de atividades de educação em saúde para as mulheres que fazem uso de anticoncepcional sobre os riscos para a trombose, bem como, a atualização frequente por parte dos profissionais de saúde para a investigação dos fatores de risco predisponentes nas mulheres em idade fértil na escolha adequada do método contraceptivo de acordo aos fatores de risco pré-existentes nas mesmas e, consequentemente, redução da possibilidade de trombose.
Contribuições do profissional da saúde no tratamento da tuberculose e fatores que influenciam o abandono na terapêutica medicamentosa
Authors: Tigre Almeida Chaves Anny Carolinny , Pires Oliveira Nayara , Quariguazy Frota Patrícia , Silva Matos Ana Carolina
Published: June 2021

A tuberculose é uma doença infectocontagiosa que acontece no Brasil desde a época da colonização e que continua sendo um grave problema de saúde pública. Os medicamentos utilizados no tratamento da tuberculose são seguros e eficazes, porém ainda se evidencia elevado abandono ao tratamento medicamentoso. Diante disso, o presente trabalho teve o objetivo de realizar uma revisão sistemática de literatura sobre o tratamento da tuberculose pulmonar e multirresistente e averiguar os fatores que impossibilitam a continuação da terapêutica medicamentosa. Trata-se de um estudo de caráter descritivo, que aborda sobre o tratamento da tuberculose e os fatores relacionados ao abandono da terapia medicamentosa. Para tanto, foi realizado um levantamento bibliográfico na base de dados eletrônica SCIELO, sendo utilizados os seguintes descritores: abandono, tratamento e tuberculose. Nesta busca foram encontrados 100 estudos, publicados entre 2000 a 2017, sendo que após a leitura do título e resumo foram selecionados 12 artigos por apresentarem maior relevância e afinidade com o tema abordado. Os trabalhos analisados sugerem que o tratamento diretamente observado realizado por um profissional de saúde no ato da dispensação dos medicamentos contribui significativamente para o seguimento e comprometimento do tratamento em busca do favorecimento da cura nos pacientes acometidos por esta doença.
The effects of body weight and pneumoperitoneum on Pleth Variability Index and Total Hemoglobin in patients undergoing laparoscopic cholecystectomy: a prospective observational study.
Authors: Patmano Gulcin , patmano mehmet , gümüş tufan , kılınç mikail
Published: June 2021

Abstract Background It is not clear if there is a inaccurate effect of
obesity and pneumoperitoneum on non-invasive monitoring parameters
Objectives To determine the effects of CO2 pneumoperitoneum and
desufflation on non-invasive monitoring variables between obese and
non-obese patients undergoing laparoscopic surgery. Methods Sixty
patients were included in the study who underwent laparoscopic
cholecystectomy between February 2019-November 2019. After anesthesia
induction, systolic and diastolic blood pressures, heart rate(HR),
operation and pneumoperitoneum durations, PVI and SpHg data were
recorded. Results The patients were divided into two groups. There was
no statistically significant difference between the groups in terms of
chronic diseases, operation and pneumoperitoneum durations.
Statistically no significant difference was found between the groups for
PVI and SpHb values. In comparison of PVI measurement values according
to T0, a significant difference was found in T3,T4 and T5 in Group 2
compared to T0 (p=0.010;0.012;0.041). In comparison of SpHb measurement
values according to T0, a statistically significant difference was found
in T1,T2 and T3 in Group 2 compared to T0 (p=0.008;0.010;0.037). In
comparison to T5, there was a significant difference in T1,T2 and T3 in
Group 2 (p=0.023;0.005;0.006). Conclusion In obese people,
pneumoperitonium can lead to inaccuracies in monitoring PVI and SpHb.
Although these two parameters are very valuable in intraoperative
follow-up, they should be used carefully during laparoscopic procedures
in obese patients. If these parameters (PVI and SpHb) are considered to
be used in bariatric surgeries, this information should be considered.
Comparison of COVID-19 outcomes with alpha-1-antitrypsin deficiency prevalence: A cross-sectional study.
Authors: Sezgin Yılmaz , Becel Sinan
Published: June 2021

Background: We hypothesized that the geographic distributions of
COVID-19 prevalence and risky alpha-1-antitrypsin allele prevalence are
similar. We aimed to investigate whether there is a relationship between
the geographical density of the COVID-19 pandemic and the distributions
of risky alpha-1-antitrypsin alleles. Methods: This research is a
cross-sectional study. Alpha-1-antitrypsin PI*SZ and PI*ZZ genotypes
frequencies of European and American countries were compared with the
case and death data related to the COVID-19 pandemic as of March 30,
2021. The relationship between the data was evaluated using Linear
regression analysis. Results: According to the linear regression
analysis results, a significant relationship was found between the
number of COVID-19 cases in both European and American countries and the
sum of PI*SZ and PI*ZZ genotypes. Similarly, according to the linear
regression analysis results, a significant relationship was found
between the COVID-19 death numbers in both European and American
countries and the sum of PI*SZ and PI*ZZ genotypes. Conclusions: The
findings showed that the prevalence distribution of the risky alleles of
the gene defect that causes alpha-1-antitrypsin insufficiency is related
to the prevalence of COVID-19 pandemic data.
COVID-19 was found in A Patient’s CSF Who Presented with A Severe form of Guillain Barre Syndrome; A Successful Sudanese Story: Case Report
Authors: Ibrahim Eetadal , Ahmed Khabab Mohamed , Sala Elmuntasir , Omer Mohammed
Published: June 2021

Neurological manifestation and complications are common due to COVID-19.
It affects higher functions, cranial nerves and the motor system. The
authors report a case of GBS as an example of a success story in
managing a complicated case of COVID-19 in an elderly male with signs of
a poor prognosis.
Resolving Severe Oligohydramnios as an Early Prenatal Presentation of Renal Coloboma Syndrome - a Report of Two Generations
Authors: Nguyen Andrew , Campagnolo Carla , Hardy Ghislain , Saleh Maha
Published: June 2021

Renal coloboma syndrome (RCS) is an autosomal dominant disorder
associated with the PAX2 gene. With variable expressivity, renal and
ocular abnormalities are reported in a majority of individuals affected.
We highlight a mother and her newborn with RCS, both presenting
prenatally, showing self-resolving severe oligohydramnios as an early
prenatal finding.
The role of roots and rhizosphere in providing tolerance to toxic metals and metalloids
Authors: Podar Dorina , Maathuis Frans J.M.
Published: June 2021

Human activity and natural processes have led to widespread
dissemination of metals and metalloids, many of which are toxic and have
a negative impact on agronomic production. Roots, as the first point of
contact, are essential in endowing plants with tolerance to excess
metal(loid) in the soil. The most important root responses include:
adaptation of transport processes that affect uptake, efflux and long
distance transport of metal(loid)s; metal(loid) detoxification within
root cells via conjugation to thiol rich compounds and subsequent
sequestration in the vacuole; plasticity in root architecture; the
presence of bacteria and fungi in the rhizosphere that impact on
metal(loid) bioavailability; the role of root exudates. In this review
we will provide details on these processes and assess their relevance
for the detoxification of arsenic, cadmium, mercury and zinc.
Furthermore, we will assess if any of these methodologies has been
tested in field conditions and whether they are effective in terms of
improving crop metal(loid) tolerance.
Levels of anxiety sensitivity, somatosensory amplification and alexithymia in patients with unexplained infertility
Authors: Koparal Buket , Gürlek Beril , Hocaoğlu Çiçek , Polat Selim
Published: June 2021

Objective: In this study, it was aimed to focus on the psychological
aspect of unexplained infertility by comparing the mental symptoms of
infertility due to known causes and fertile patients. Patients and
Methods: 60 unexplained infertility patiens, 50 infertile patients with
a known cause and 56 fertile patients were included in the study.
Socio-demographic data form, Toronto Alexithymia Scale (TAS-20),
Somatosensory Amplification Scale (SAS) and Anxiety Sensitivity Index
(ASI-3) were applied to the patients. Results: No significant
differences in the levels of alexithymia, somatosensory amplification,
and anxiety sensitivity were detected across the groups
(p>0.05). When the correlation of clinical scale scores
with each other was analyzed in the whole group of infertile patients
regardless of the cause, anxiety sensitivity was found increased as
difficulty identifying feelings increased. Conclusion: In our study, it
has been found out that; regardless of the knowledge of the etiology of
infertility, the levels of alexithymia, somatosensory amplification, and
anxiety sensitivity of infertile cases did not differ from those of
fertile women. However, it has been shown that as the difficulty in
identifying emotions increases in infertile cases, anxiety sensitivity,
which may cause psychological infertility, also increases.
Selective Influence of Cyflumetofen in Degradation and Ecological Risk Assessment
Authors: Shi Linlin , Zhang Ping , Chen Qi , Yang Cancan , Zhang Daqi , Xu Jun , He Lin
Published: June 2021

Pesticide pollution has gradually caused land degradation. In order to
avoid this problem, it is recommended to use enantiomeric pesticides
that have less impact on the soil. The degradation of CYF enantiomers
and the effect on soil functions are closely related to microorganisms.
(+)-CYF enantiomer is degradable preferred and further discovered that
related microorganism that degrades enantiomers. CYF enantiomers alter
the bacteria structure and decreased the bacteria abundance. The
combination of high-throughput and quantitative PCR results showed that
the diversity of the (+)-CYF treatment was significantly lower than that
of the (-)-CYF (-30.41 to 44.60) treatment and the (+)-CYF treatment
(-27.80 to 56.70%) was more capable of causing the decrease in the
number of soil microorganisms. In addition, (+)-CYF severely interferes
with nitrogen cycling-related functions. Furthermore, the soil microbial
structure was changed to its original level by enantiomers posed. In the
study of nitrogen cycle function, we found that both enantiomers can
restrain the abundance of nitrogen cycle-related genes, especially the
(+)-CYF treatment decreased more. CCA showed that g-Massilia and
g-Arthrobacter are closely related to nitrogen fixation genes and
nitrification genes and degradation of the two enantiomers of CYF by
g-Arthrobacter is closely related. The biological effects of
cyflumetofen enantiomers remain unclear. Bioassay results show that
enantiomers have similar virulence to Tetranychus cinnabarinus.
Therefore, while achieving the prevention and control effect, the use of
a single isomer (+)-CYF has a higher potential risk to the soil
ecosystem.
Industrial By-Products for the Rehabilitation of Coal Mining-Affected Areas -- a Novel Approach
Authors: Bauerek Arkadiusz , Diatta Jean , Pierzchała Łukasz , Krzemień Alicja , Więckol-Ryk Angelika
Published: June 2021

The blends of coal combustion by-products (CCBs) with organic wastes
(sewage sludge and spent mushroom compost) were investigated for
elaboration of soil substitutes for land rehabilitation of coal mine
affected areas. The study incudes four types four types of habitat with
different water retention and fertility i.e.: dry and moderate fertility
(A1-A3), mesic and low fertility (B1-B3), mesic and moderate fertility
(C1-C3), humid and low fertility (D1-D3). Obtained results revealed that
the amounts of macronutrients were sufficient for supporting plant
growth i.e.: N (0.44-0.60 %), P (0.13-021 %), K (1.63-1.98 %), Mg
(1.01-1.38 %), Ca (5.32-8.23 %), S (2.66-4.12 %), whereas the
concentration of organic matter varied within the range 20.3-27.9 %.
Phytotest using white mustard (Sinapis alba) seeds under laboratory
conditions showed that the best results of sprouting i.e: 56 and 66 %
were obtained for D2 and D3, respectively. The values of pH (8.16-8.78)
and electrical conductivity (5.28-6.73 mS·cm-1) of tested soil
substitutes were found to be the decisive factors limiting the
germination process. The coefficients between the parameters of soil
substitutes and the Sinapis alba sproutings have revealed negative
correlation with electrical conductivity (r = -0.46). Additionally,
tests with meadow vegetation gave promising opportunity for the use of
soil substitutes in the process of land rehabilitation. The cover of the
mesic and dry meadow vegetation reached 90%. The Principal Component
Analysis (PCA) has outlined that pH, content of P and organic matter,
are the most important factors that influence cover of meadow
vegetation.
C4C - Paediatric pharmacovigilance: Methodological Considerations in Research and Development of Medicines for Children – A c4c Expert Group White Paper
Authors: Aurich Beate , Apele-Freimane Dina , Banaschewski Tobias , Chouchana Laurent , Day Simon , Kaguelidou Florentia , Kelly Lauren E , Kindblom Jenny , Neubert Antje , ASSIGNMENTS) Ian Wong (NO NEW
Published: June 2021

Children frequently respond differently to therapies compared to adults.
Differences also exist between paediatric age groups for
pharmacokinetics and pharmacodynamics in both efficacy and safety.
Paediatric pharmacovigilance requires an understanding of the unique
aspects of children with regards to, for example, drug response, growth
and development, clinical presentation of adverse drug reactions (ADRs),
how they can be detected and population specific factors (e.g. more
frequent use of off-label/unlicensed drugs). In recognition of these
challenges a group of experts has been formed in the context of the
conect4children (c4c) project to support paediatric drug development.
This expert group collaborated to develop methodological considerations
for paediatric drug safety and pharmacovigilance throughout the
life-cycle of medicinal products which is described in this article.
These considerations include practical points to consider for the
development of the paediatric section of the risk management plan (RMP),
safety in paediatric protocol development and safety data collection and
analysis. Furthermore, they describe the specific details of
post-marketing pharmacovigilance in children using, for example,
spontaneous reports, electronic health care records, registries and
record-linkage, as well as the use of paediatric pharmacoepidemiology
studies for risk characterisation. Next the details of the assessment of
benefit-risk and challenges related to medicinal product formulation in
the context of a Paediatric Investigation Plan (PIP) are presented.
Finally, practical issues in paediatric signal detection and evaluation
are included. This paper provides practical points to consider for
paediatric pharmacovigilance throughout the life-cycle of medicinal
products for RMPs, protocol development, safety data collection and
analysis and PIPs.
The Predictive Value of left atrial appendage peak flow velocity in Recurrence after initial radiofrequency catheter ablation of persistent atrial fibrillation: A single-center prospective study.
Authors: Yang Wentao , Zhao Qing , Yao Minghui , Li Xiangdong , Zhang Yue , Liu Chuanbin , Shan Zhaoliang , Wang Yutang
Published: June 2021

Background: Recurrence after Radiofrequency catheter ablation（RFCA） of
persistent atrial fibrillation (PeAF) is still elusive. The present
study aimed to evaluate the relationship between the left atrial
appendage peak flow velocity(LAAV) and atrial fibrillation(AF)
recurrences in PeAF patients after their initial RFCA. Method: This
study included 164 consecutive PeAF patients who performed initial RFCA
from January 2018 to December 2019. Transesophageal echocardiography was
used to collect the LAAV before ablation. Patients’ demographic and
clinical information was gathered. To detect the recurrences of AF,
patients were checked up at routine intervals. A Cox proportional
hazards regression analysis was adopted to evaluate the LAAV and other
clinical variables as predictors of AF recurrences throughout follow-up.
Results: AF recurrence resulted in 43 (26.2%) patients after a median
follow-up of 15 months (IQR: 12-18 months). LAAV reduced in patients
with AF recurrences (0.36±0.15m/s vs. 0.45±0.17m/s, P = 0.004). A
Kaplan-Meier study revealed that the low LAAV(≤0.37m/s) group had a
lower event-free survival rate than the high LAAV
(>0.37m/s) group (17.6 months vs. 21.2 months, Log Rank P =
0.002). LAAV≤0.37m/s (HR 2.32, 95%CI 1.177-4.227, P = 0.014) was found
to be independent predictors of AF recurrence after RFCA in the
multivariate Cox regression. Conclusion: A low LAAV is linked to AF
recurrence and acts as a predictor of AF recurrence after the initial
RFCA of peAF. This would aid in treatment strategy optimization and
management of patients with peAF.
Sosiaalityön tiedollisten tarpeiden huomioiminen tietojärjestelmä Apotissa
Authors: Salovaara Susi
Published: June 2021

Tietojärjestelmistä on tullut keskeinen osa sosiaalityötä. Sosiaalityön tietojärjestelmien avulla tuotetaan tietoa eri tahoille, kuten asiakkaille, työntekijöille, johtajille ja päättäjille. Erilaisten tiedollisten tarpeiden huomioiminen tietojärjestelmässä on haastava tehtävä, joka vaatii sosiaalityön ja tietojärjestelmän käyttöympäristön tuntemusta.
Tutkimuksessa kysyttiin, miten sosiaalityön tiedollisia tarpeita on tulkittu, tunnistettu ja ratkaistu tietojärjestelmän kehittämistyössä. Tutkimuksen kohteena oli Apotti-tietojärjestelmän sosiaalihuollon sovellus. Tutkimusaineisto muodostui Apotin sosiaalihuollon sovelluskehitykseen osallistuneiden asiantuntijoiden fokusryhmähaastatteluista. Aineisto analysoitiin teoriaohjaavalla sisällönanalyysillä.
Tuloksina kuvataan, miten Apotti-hankkeessa tunnistettujen sosiaalityön tiedollisten tarpeiden tietojärjestelmälle asettamissa vaatimuksissa korostuu tiedon hyödynnettävyys, kokonaisvaltaisuus ja ajantasaisuus asiakaslähtöisen sosiaalityön, työprosessien hallinnan, tiedolla johtamisen ja tietoperustaisen sosiaalityön näkökulmista. Tietojärjestelmän on tuettava olennaisen tiedon hahmottamista, työtehtävien seurantaa, dataohjautuvaa johtamista ja sosiaalityön tutkimusperustaisuuden vahvistamista sekä tietoturvallista viestintää asiakkaiden ja ammattilaisten kesken. Tietojärjestelmän osaava ja yhtenäinen käyttö on kriittinen tekijä tavoiteltujen hyötyjen toteutumiselle ja korostaa tietojärjestelmän käyttäjien riittävän koulutuksen merkitystä.
Validation of the wearable sensor system - MoveSole® smart insoles
Authors: Alamäki Antti , Nevala Elina , Jalovaara Juha , Barton John , Tedesco Salvatore , Condell Joan , Muñoz Esquivel Karla , Kelly Daniel , Heaney David , Gillespie James , Karim Shvan , Davies Richard , Nordström Anna , Åkerlund Larsson Markus
Published: June 2021

Biomechanical analysis of gait is commonly used in physiotherapy. Ground reaction forces during phases of gait is one element of kinetic analysis. In this article, we analyze if the MoveSole® smart insole is valid and accurate equipment for measuring ground reaction forces in clinical physiotherapy. MoveSole® StepLab is a mobile measurement system for instant underfoot force measurements during gait. Unique electromagnetic film (EMFI) based sensor technology and printed electronics production technology is integrated in the MoveSole® StepLab measurement system. The MoveSole® StepLab measures plantar ground reaction force distribution over the sensors and provides an estimation of the maximum total ground reaction force.
We developed a two phase validation process to extract relevant parameters and compared the results to a Kistler force plate using the BioWare® analyzing program as a reference method. Our results show that MoveSole® smart insoles reach the strong level of accuracy needed in clinical work concerning highest ground reaction forces during step (Pearson correlation .822 - .875). The correlation of the time when the maximum ground reaction force occurred was moderate, e.g. during heel strike or toe-off (Pearson correlation natural gait speed .351 - .462, maximum gait speed .430). Our conclusion is that MoveSole® smart insoles are a potential tool for analyzing and monitoring gait ground reaction forces during physiotherapy processes.
Sähköisten oirearvioiden käytettävyys
Authors: Liu Ville D , Sellgren Lasse , Kaila Minna , Koskela Tuomas
Published: June 2021

Kunnat uudistavat terveydenhuolto- ja sosiaalihuoltopalveluitaan ja luovat sähköisiä palveluita potilaiden omahoidon tueksi (Omaolo-projekti). Näihin kuuluvat 15 eri oireisiin keskittyvää sähköistä oirearviointityökalua. Täytetyn oirearvion tuloksena potilas saa arvion vastaavan oireen hoidon tarpeen kiireellisyydestä, ohjeet hoitopaikan valitsemisesta sekä tarvittaessa itsehoito-ohjeita. Tässä tutkimuksessa tutkitaan oirearvioiden käytettävyyttä potilaan ja tutkimusavustajan näkökulmasta.
Tämä on monimenetelmä tutkimus, joka käytti Omaolo-projektin oirearvioiden validointi tutkimuksessa kerättyjä tietoja. Tiedot kerättiin 18:sta perusterveydenhuollon päivystyspisteistä ympäri Suomea. Käyttäjä vastasi oirearvion esittämiin kysymyksiin, minkä jälkeen hoidon tarpeen arviointiin perehtynyt sairaanhoitaja arvioi käyttäjän oireen hoidon tarpeen. Tutkimusavustaja seurasi käyttäjän oirearvion täyttämisen. 350:n yksittäisen potilaskäyttäjän, sairaanhoitajien ja tutkimusavustajien havainnot analysoitiin erillisten täytettyjen tutkimuslomakkeiden pohjalta. Teema-analyysin avulla luotiin tutkimusteemoja tutkimukseen osallistuneiden henkilöiden kirjatuista havainnoista. Analysointivaiheessa havainnot ryhmiteltiin teemoihin, mitä seurasi vastaavien koodien ja temaattisen yhteenvedon laatiminen.
Oirearvioiden käytettävyys arvioitiin pääosin hyväksi. Haasteita käytettävyydessä myös ilmeni. Haasteita kuvaavia merkityksellisiä käsitteitä (koodeja) muodostettiin tutkimuslomakkeiden vapaan tekstin havainnoista. 59 kappaletta koodeja luokiteltiin kahteen pääteemaan - käyttäjäkohtaisiin syihin ja oirearviolähtöisiin syihin. Käyttäjäkohtaiset syyt jaettiin: a) haasteisiin sähköisen oirearvion ja sen kysymysten tulkinnassa, b) sähköisten työkalujen käyttövalmius ja c) potilaan kyky arvioida omaa terveydentilaansa. Oirearviolähtöiset syyt jaettiin: a) Oirearvioissa käytettävään terminologiaan ja kysymysasetteluun liittyvät tekijät ja b) visuaaliseen muotoiluun ja käyttäjän ohjeistukseen liittyvät tekijät.
Oirearviot ovat suurimmalle osalle potilaista hyväksyttäviä, helppokäyttöisiä ja ymmärrettäviä. Tutkimuksessa tuli esiin teemoja, jotka saattavat heikentää oirearvioiden käytettävyyttä. Oirearvioiden käytettävyyttä parantamalla voidaan parantaa hoidon tarpeen arvioinnin prosessia sekä sen onnistumista. Käytettävyyteen liittyvät ongelmat voivat heikentää potilaan halukkuutta käyttää oirearvioita.
Persistence of SARS-CoV-2 in deceased patients and safe handling of infected bodies
Authors: Schegolev AI , Tumanova UN
Published: June 2021

This article analyzes the literature on SARS-CoV-2 persistence in the corpses of patients infected with COVID-19, possible routes of viral transmission from the bodies and biosafety measures to prevent the spread of the infection. SARS-CoV-2 persists for quite long in the tissues and bodily fluids of decedents with COVID-19 and on various surfaces. The longest viability of the virus is on stainless steel and plastic surfaces that come in contact with the infected body. Autopsies on decedents with COVID-19 must be performed at specially conditioned facilities. Medical and forensic pathologists and other mortuary workers must adhere to stringent biosafety requirements.
Business and the internal control system of the audited entity
Authors: Zatsarinnaya Elena Ivanovna , Prodanova Natalia Alexeevna , Guskov Sergey Viktorovich , Sotnikova Lyudmila Viktorovna , Kosnikova Oksana Vladimirovna , Kalyakina Inessa Makedonovna
Published: June 2021

An important section in any well-functioning company is the internal control system. As one of the functions of management activities, which determines the quantitative and qualitative assessment of the company's performance, control helps to identify vulnerabilities in the company in a timely manner. The fundamental purpose of this work is to study the internal control system and to disclose the concept of the audited entity's business from the theoretical and practical side. In the course of the study, the authors concluded that in order to build an effective internal control system, it is necessary to develop subsections in business processes that lead to control at each process chain.
Process and risk-based principles of internal control in the organization's management system
Authors: Zatsarinnaya Elena Ivanovna , Mailyan Alexey Armenovich , Prodanova Natalia Alekseevna , Sotnikova Lyudmila Viktorovna , Guskov Sergey Viktorovich , Kosnikova Oksana Vladimirovna
Published: June 2021

The main criteria for successful enterprise management are efficiency and effectiveness, and control as one of the management functions, in fact, is aimed at ensuring them. At the same time, the modern system of internal control often goes beyond financial regulation and becomes a single entity with the quality management systems of the organization, providing monitoring of the efficiency and effectiveness of entire business processes. The relevance of internal control issues increases due to the growth of economic instability and the emergence of new risks. At the same time, there is currently no effective practice of implementing internal control systems based on process-based and risk-based approaches, and the scope of regulation of these processes differs both in the methodological (recommendatory) nature of the acts themselves and in the inconsistency of their content.
Pedagogy of partnership in inclusive education of the EU countries
Authors: Piekharieva Alona , Omelchenko Iryna , Кobylchenko Vadym , Pikanova Natalia , Petrykina Anna
Published: June 2021

The purpose of the academic paper was to identify the features of partnership pedagogy on a practical level in inclusive education in the EU countries. A qualitative methodology was used in the research based on content analysis and the meta-analysis of publications for 2015-2020 on the issues of partnership pedagogy based on interprofessional interaction of different professionals, parents and children. The results have revealed that partnership in inclusive education is a style of interaction characterized by voluntary participation. In the process of interaction, interested parties transform beliefs, values and form knowledge about the most effective inclusion strategies. Understanding the peculiarities of the psychophysical development of a child with special needs provides effective inclusion. The child’s adaptation depends on the level of adult’s understanding of the child’s educational needs, considering his opinion in decision-making in problematic learning situations. The child’s role as a full-fledged partner in inclusion determines the level of adaptation in the educational environment.
FORMALISASI HUKUM ISLAM DALAM BENTUK PERATURAN DAERAH: ANALISIS PERATURAN DAERAH SYARIAH DI BULUKUMBA
Authors: Syatar Abdul , Juliana Juliana , Eitriya Zehratul , Rifaldi Rifaldi , Winanda Winanda , Anugrah Alfajri , Putri Angelina Atika
Published: June 2021

This article aims to examine the formalization of Islamic law in the form of a Sharia Regional Regulation (Perda) in Bulukumba. The approach in this research is juridical-normative. This approach is used to understand the phenomenon of the formalization of Islamic law in the Bulukumba area. The results show that the formalization and application of sharia regulations in Bulukumba is running quite well, this is based on the development of public understanding and compliance with the Perda. On the other hand, these sharia-based regulations sometimes run less effectively. This is because there are still many Bulukumba people who do not know, let alone understand the Sharia Regional Regulations well.
PRAKTIK TRANSAKSI NON TUNAI MELALUI LAYANAN SYARIAH LINKAJA PADA EKOSISTEM KEISLAMAN DI KOTA CIREBON
Authors: Lusiana Nisa , Muamar Afif , Wasman Wasman , Sukardi Didi
Published: June 2021

The rise of non-cash transactions today has made people tend to switch from manual transactions that use cash to electronic transactions. LinkAja Syariah service is an application-based electronic money service designed to facilitate user transactions. LinkAja Syariah Services prioritizes three main categories of sharia service products, namely the ZISWAF, mosque-based economic empowerment and digitization of Islamic boarding schools, micro small and Medium Enterprises. Thus, this study seeks to reveal the contribution of LinkAja Sharia Services in the city of Cirebon, where the majority of the population is Muslim and there are many religious institutions. This study aims to determine the practice of using LinkAja Syariah Services in Cirebon City from an Islamic law perspective. The method used in this research is qualitative by inductive means, that is, from data to a higher level of abstraction, including synthesis and theory development (if necessary and the data supporting). This means that data analysis in qualitative research is more open-ended and must be adjusted to data in the field, such as the results of interviews, observations, and documentation. In addition, the data analysis technique used in this study was qualitative analysis as stated by Miles and Hubberman, namely data collection, data education, data presentation and conclusion drawing. The results of this study are: LinkAja Sharia services that prioritize three main products, namely the ZISWAF ecosystem, mosque-based economic empowerment, and digitization of Islamic boarding schools and UKM. In Cirebon City LinkAja Syariah services can be used for zakat, infaq and shodaqoh payments at LAZISMU Cirebon Regency, donations at At-Taqwa Mosque, and shopping at traditional markets such as Gunung Sari Market, PGC Morning Market, and Kanoman Market
PENINGKATAN EKONOMI UMAT MELALUI ZAKAT PROFESI DAN ZAKAT PRODUKTIF
Authors: Dg. Mustafa Muhtadin
Published: June 2021

Tulisan ini merupakan sebuah kerangka pikir tentang Peningkatan Ekonomi Umat Islam melalui Pemberdayaan Zakat Profesi Dan Zakat Produktif. Pengelolaan zakat di masyarakat yang mayoritas beragama Islam memberikan keyakinan bahwa Zakat dapat digunakan sebagai instrumen penting dalam pembangunan ekonomi umat Islam. Satu hal penting lain adalah membenahi setiap UPZ (Unit Pengelolaan Zakat) yang ada agar dapat menerapkan prinsip-prinsip manajemen modern dalam pengelolaan zakat agar tercipta akuntabilitas publik dan transparansi kepada lembaga ini dapat meningkat dan mendapatkan kepercayaan dari muzakki secara terus menerus. Pemerintah dapat menggunakan sistem pengumpulan dan pengelolaan zakat sebagaimana diterapkan pada pengumpulan pajak negara, sehingga potensi zakat dapat dimanfaatkan oleh negara dan dinikmati oleh masyarakat khususnya umat Islam Indonesia. Untuk mewujudkan cita-cita tersebut pemerintah perlu menyiapkan petunjuk teknis tentang zakat sehingga dapat berjalan dengan baik, agar bisa lebih banyak manfaatnya dalam pertumbuhan ekonomi umat Islam di Indonesia.
Editorial
Authors:   Universidad de San Martín de Porres, Perú, Fernández-Arata Manuel
Published: June 2021

Liberabit, Revista Peruana de Psicología is pleased to share with the national and international academic community, seven research articles corresponding to the first issue of volume 27 of this year. We begin this presentation with the work of Nelson Castro, Ximena Suárez and Enrique Barra, who examine the relationship of emotional regulation difficulties and personality variables with life satisfaction in Chilean university students, finding that they are significantly associated; also, that responsibility and neuroticism are predictors of life satisfaction, highlighting the importance of the ability to deal with emotions and accept them in the educational process. Alejandro Emilio Pagano and Nicolás Alejandro Vizioli evaluated the temporal stability and discriminant validity of the Beck Anxiety Inventory in Argentine participants, reporting evidence of good temporal stability, since error sources do not significantly affect the scores, as well as an adequate discrimination capacity, mainly to be able to distinguish anxiety from depression.
Factores vinculados al bullying en escolares de Córdoba, Argentina
Authors:   Universidad Nacional de Córdoba, Argentina, Cardozo Griselda
Published: June 2021

Antecedentes: el bullying es un problema complejo por lo que las investigaciones sugieren poner el foco en las características individuales de los adolescentes, así como explorar aquellos contextos que inciden en su desarrollo, como el familiar y escolar, adoptando una visión ecológica. Objetivo: indagar los factores individuales (comportamientos prosociales/antisociales) y las características de los contextos familiares y escolares vinculados a la conducta de bullying en adolescentes escolarizados de escuelas públicas y privadas de la ciudad de Córdoba. Método: se administró una batería de test para medir las variables en estudio a 3500 adolescentes entre 11 y 20 años. Se realizó un análisis de correspondencia múltiple. Resultados: se detectan dos dimensiones que explican un 36.47% de la variabilidad de los datos, como ejes estructurales del espacio de las representaciones, que identifican los patrones sobre los que se discriminan los roles implicados en el bullying. Se verifica que las víctimas comparten más características con los no implicados y los agresores con el grupo denominado víctimas-agresores, constatando que los roles ante el acoso no son excluyentes. Conclusión: la identificación de los diferentes factores se constituye en un insumo valioso para el diseño de intervenciones orientadas a la prevención.