bluuebunny/crossref_metadata_2025 huggingface dataset:
Vocabulary and Syntax Reception in Children with Down Syndrome
Authors: Ashrafi Fatemeh , Arshi Bahar , Mohammadi Reyhaneh , Zarei Faskhodi Bentolhada , Rasouli Mahboobeh
Published: April 2023

Introduction: Intellectual disability and specific cognition in down syndrome (DS) affect language development and processing. We assessed vocabulary and syntax reception among children with DS with typically developed (TD) Persian-speaking Iranian children. We also investigated the association between vocabulary and syntax reception in children with DS.
Materials and Methods: Using the Stanford–Binet intelligence scales test, 18 TD children (4-6 years old) and 18 DS children were matched based on non-verbal mental age. Vocabulary reception was assessed using the receptive picture vocabulary test (RPVT) and syntax reception by the Persian syntax comprehension test.
Results: Mean total vocabulary reception was lower in children with DS (P<0.001). Syntax reception was also impaired in children with DS compared to the normal values of the test. Among children with DS, vocabulary reception was positively correlated with syntax reception. Every unit increase in total vocabulary reception score was associated with 0.08 (95% confidence interval, CI: 0.04-0.12) improvement in syntax score in children with DS.
Conclusion: Vocabulary and syntax reception in DS children, especially complex syntax structures, was impaired. The observed association between vocabulary and syntax reception shows that vocabulary reception improvement might result in progressing syntax reception in children with DS.
Distribution Pattern of Refractive Errors in Strabismic Iranian Children
Authors: Kangari Haleh , Masoomian Babak , Khorrami-Nejad Masoud , Fawzi Hasan Alshmailawi Sarah , Eidi Faezeh
Published: April 2023

Introduction: The purpose of the present study was to determine the refractive profile of strabismic children under 8 in a tertiary referral center in Tehran, Iran.
Materials and Methods: This retrospective cross-sectional study was conducted on the medical records of 357 patients under the age of 8 who had one type of strabismus in Farabi Hospital, Tehran, Iran, between 2015 and 2019. All routine ophthalmic examinations were done for all patients. Cycloplegic refraction was performed after the instillation of two drops of cyclopentolate 1% with an interval of 5 minutes, and the refractive error was measured after 30 minutes. The diagnostic criteria were based on cycloplegic refraction in which myopia, hyperopia, and astigmatism were defined when the refractive error was -0.25, +0.75, and -0.50 diopter (D) or more, respectively. The cycloplegic results were classified into different groups with an interval of 1.00 D, and astigmatism was also assessed separately.
Results: In this study, the most common type of refractive error in esotropic patients was hyperopia, with the +2.00 to +4.00 D range having a higher prevalence. In exotropic patients, hyperopia was also prevalent; the most common range of hyperopia was between +0.75 to +1.00 DA Astigmatism had a prevalence of 8% in esotropic patients, and 17.2% in exotropic patients with the most common range from -0.50 to -1.00. Myopia was present in 2.8% of patients with esotropia and 3.2 % of patients with exotropia with the most common range from -0.25 to -1.00.
Conclusion: In strabismic Iranian children, hyperopia was the most prevalent refractive error in both esotropic and exotropic patients, with higher degrees of hyperopia in esotropic patients. Low astigmatism was twice as prevalent in patients with esotropia as in patients with exotropia. Low myopia was the least prevalent in both esotropic and exotropia.
Languag Skills in	Preschool Children with Down Syndrome and Non-verbal Mental Age-matched Controls
Authors: Aminian Monireh , Karbalaei Sadegh Mahnaz , Salmani Masoomeh , Naeemi Ali Jafari
Published: April 2023

Introduction: Down syndrome (DS) as a chromosomal abnormality has different symptoms including cognitive problems and language delay.  Studies showed a heterogeneous profile   of language skills in this group of children. This study aimed to provide further information about the most vulnerable area of language -grammatical skills- regarding the unanalyzable utterances, clauses, phrases, grammatical morphemes, and mean length of utterances (MLU) in children with DS and compare them with those of non-verbal age-matched controls.
Materials and Methods: The grammatical structures of 12 children with DS (non-verbal age=39 months) were compared to those of 50 non-verbal mental age-matched controls (non-verbal age=41 months). Clause, phrase, and grammatical morphemes were investigated through spontaneous language sample analysis according to Persian-language assessment remediation and screening procedure (P-LARSP).
Results: Children with DS had higher percentages of unanalysable text units compared with typically matched peers (P≤0.001). The MLU, number of phrases and clauses structures, and inflectional morphemes were significantly lower in children with DS compared with typical children (P<0.001).
Conclusion: Children with DS showed a noticeable gap in grammatical structures compared with typical children. The possibility of specific language problems in children with DS should be considered by future studies.
Comparison of Knee Proprioception between Athletes with Anterior Cruciate Ligament Injury and Healthy Athletes
Authors: Naghizad Javad , Emami Meibodi Mohamad Kazem , Dalvand Hamid , Shamsoddini Alireza
Published: April 2023

Introduction: In addition to the instability of the knee joint, injury to the anterior cruciate ligament (ACL) leads to a functional deficit in the form of diminished proprioception of the knee joint. The purpose of this study was to compare knee proprioception in athletes with an ACL injury and healthy athletes.
Materials and Methods: The participants  in this cross-sectional  study were 26 athletes  with an ACL injury and 24 healthy athletes who were selected from the orthopedic clinic at Baqiyatallah Hospital in 2019, Tehran City, Iran. Cooper or non-Cooper subjects with ACL injury were identified via the knee injury and osteoarthritis outcome score (KOOS). The  knee proprioception of all participants was recorded using a system consisting of digital photography, non-reflective markers, and Digimizer software.
Results: The results showed that there was no significant difference between groups in the absolute error of knee joint reconstruction at both 45° and 90° angles.
Conclusion: The data of the study showed that in comparison with healthy athletes, the knee joint proprioception of athletes with an ACL injury is not different and has the same function.
Postural Stability Changes Following Static Loading in Athletes with and without Anterior Cruciate Ligament Reconstruction
Authors: Ferdowsi Forough , Shadmehr Azadeh , Mir Seyed Mohsen , Olyaie Gholamreza , Keyhani Sohrab
Published: April 2023

Introduction: This study investigated the effect of change in postural stability after applying static load during internal perturbation among professional athletes with and without anterior cruciate ligament (ACL) surgery.
Materials and Methods: The participants of the present study were 20 athletes with sixteen months post ACL reconstruction surgery and 20 healthy matched athletes. Each participant performed transitional tasks from double limb stance to single leg stance (SLS) and again to double limb stance on the force plate before and after the application of 10 minutes of constant loading. Area, fore-after range (the meaning of fore-after is anterior- posterior and in articles, this term has been used instead of anterior-posterior) range fore- after (Rfa), range sideway (Rsw), mean velocity (Mv) and confidence ellipse (Ce) of the center of pressure were measured.
Results: Rsw (P=0.009) and area (P=0.009) in response to static loading in the healthy group showed a decrease and an increase of area (P=0.009) in response to static loading in the ACLR group was seen on the double limb stance phase. Mv (P<0.001) and area (P<0.001) were bigger in the ACLR group after static loaded on the integration phase.
Conclusion: Decreased capacity of passive structures to maintain postural stability against perturbation was observed due to positional change among athletes with a history of ACL reconstruction surgery.
Effect of Proprioceptive Training on Reaction Time: A Randomized Control Trial
Authors: Mazbouh Rami Kassem , Ziab Hussein , Farhat Itab , Shadmehr Azadeh
Published: April 2023

Introduction: Reaction time is an important indicator of good performance. Different types of exercises have been used by researchers to improve the reaction time of an individual. Other types of exercises still need more research to study their effect on simple reaction time, such as proprioceptive training. The purpose of this study is to examine the effect of a proprioceptive training program using the Huber machine on the simple reaction time.
Materials and Methods: Twenty-one participants from the medical staff were assigned to two groups including the experimental group (1) composed of 5 male and 5 female participants and a control group (2) including 5 male and 6 female participants. A simple reaction time (SRT) test was assigned to all participants. Only the experimental group performed a proprioceptive exercise protocol on Huber motion’s platform, while the control group was tested at identical periods without exercising before the training (T0), immediately post-exercise (T1), and twenty minutes after exercising (T2). The procedure was repeated for six sessions over two weeks.
Results: The participants of the group (1) show a decrease in the mean of RT (-43 min) immediately after proprioceptive training (T1), but they reveal a little increase (at T2) in   SRT after an interval of 20 minutes (-23 min). They still prove a retention effect, while few participants in the control group show improvement at T1 or T2. Paired sample t-test was significant for the group (1) at T1 and T2 (P<0.05) while it was not significant for the control group.
Conclusion: Proprioceptive training may have a positive influence on reaction time with a retention effect. Clinicians can use proprioceptive training to improve the reaction time of their patients.
Effects of Blood Flow Restriction on Pain and Muscle Thickness Following Tendinopathy: A Case Study
Authors: Poursaleh Begi Zahra , Bashardoust Tajali Siamak , Mir Seyed Mohsen , Talebian Saeed , Shadmehr Azadeh , Ashnagar Zinat
Published: April 2023

Introduction: Blood flow restriction (BFR) training, in which an inflatable cuff partially occludes blood flow around the proximal portion of a limb, coupled with low-load resistance exercise (LLRE) has resulted in gains comparable with traditional progressive resistive exercise in healthy populations. The use of BFR with LLRE may help people with supraspinatus tendinopathy through proximal effects to improve strength and muscle size. The purpose of this case report is to describe the proximal effect of the LLRE+BFR program on a patient with supraspinatus tendinopathy.
Materials and Methods: The patient was a 40-year-old man with a history of shoulder pain and weakness for the past months. He received an LLRE+BFR program for his right shoulder including rotator cuff and scapular strengthening exercises and lower limbs aerobic exercises based on protocols of strengthening and aerobic exercises of BFR. Outcomes measured at baseline and 4 weeks included the 4 items: 1) Strength of supraspinatus muscle and four scapular stabilizer muscles including serratus anterior strength, middle trapezius strength, and lower trapezius strength by dynamometer, 2) supraspinatus thickness by ultrasound, 3) pain pressure threshold of supraspinatus and deltoid muscles by algometer, and 4) pain reported bay in each session based on pain numeric scale.
Results: After 6 weeks, the strength of supraspinatus and scapular stabilizers except for the lower trapezius increased. The supraspinatus thickness and pain pressure threshold in the supraspinatus and deltoid muscle also increased after 4 weeks. The mean of pain reported by the patient based on the pain numeric scale before and after each session was also decreased.
Conclusion: The patient had measurable improvements following the use of an LLRE+BFR program. LLRE+BFR program may be an option for strength training in people with supraspinatus tendinopathy; however, more research is needed to determine effectiveness across the population of people with supraspinatus tendinopathy.
Resistance Training in Wilson Disease: A Case Study
Authors: Chakeri Zahra , Talebian Saeed
Published: April 2023

A 15-year-old boy was diagnosed with Wilson disease and referred to a physiotherapy clinic for treatment. He received daily physical therapy exercises with resistance training three times a week for 70 minutes for 8 weeks. The performance of daily activities was evaluated using the Persian version of the disabilities of the arm, shoulder, and hand (DASH) questionnaire. Upper limb muscle strength was assessed using a manual muscle strength test. The DASH questionnaire score decreased from 67.24 before treatment to 46.55 after 4 weeks and 36.20 after 8 weeks. In addition, shoulder flexion and extension are improved. The analysis of resistance exercises to facilitate distal muscles through the use of manual muscle tests showed an improvement in the strength of both hands. The present study suggests that regular physical therapy and exercise may help improve daily activity and muscle strength in Wilson disease.
Historical Relationship between Cardia and Heart
Authors: Abdoli Mahsima , Mahlooji Kamran
Published: April 2023

The Article Abstract is not available.
Antinociceptive Effects of Paeonia daurica subsp. macrophylla Root Extracts in Mice
Authors: Monsef-Esfahani Hamidreza , Jamshidi Sahand , Sharafi-Badr Paria , Sharifzadeh Mohammad , Vazirian Mahdi , Sadati Lamardi Seyede Nargess
Published: April 2023

This study aimed to assess the antinociceptive activity of extracts and fractions of Paeonia daurica subsp. macrophylla in BALB/c mice. Various doses of hydro-alcoholic extract (HE), hexane fraction (F-hexane), methanol (F-MeOH), and chloroform (F-CHCl3), as well as aqueous extracts (AE), were evaluated by a well-known model, a formalin-induced pain test in mice. All extracts, piroxicam 0.1 mg/kg, and negative control groups were administered 30 minutes before formalin injection. Flinching, licking, and biting reflexes were measured as painful factors compared with controls at intervals of 0 to 5 minutes, 0 to 15, and 0 to 60 minutes after formalin injection. The acute oral toxicity test of total ethanolic and aqueous extracts showed no signs of toxic effect up to a dose of 5000 mg/kg. In the formalin test at a time interval of 0 to 5 minutes, there was no significant difference between the results of the study groups. In the range of 0 to 15 minutes, the effect of AE (1 g/kg), HE (2, 3 g/kg), and F-hexane (1 g/kg) was significantly higher than the positive control group (p<0.01). In the time interval of 0 to 60 minutes as the total time of the experiment, the effect of AE (0.25 g/kg), AE (0.5, 1 g/kg), HE (2, 3 g/kg), F-hexane (1 g/kg) were significantly different than the positive control group. It can be concluded that extract of P. daurica subsp. macrophylla might be helpful in the treatment of pain in humans.
Development, Characterization, and In Vitro Antimicrobial Activity of Lawsonia inermis L. Leaves Hydroalcoholic Extract-Based Vaginal Suppositories
Authors: Firdous K Fakeha , Rahman Khaleequr , Sultana Arshiya , Khan Shamsiya
Published: April 2023

Lawsonia inermis L. (henna) leaves have good antimicrobial, anti-inflammatory and wound healing properties. It is used topically in the form of hamul in gynaecological infections in traditional medicine. However, due to the unpleasant dosage form, it has very low patient compliance. Hence, in this study hydroalcoholic extract-based vaginal suppository of henna leaves was formulated and evaluated for various parameters. Multiple batches of suppository were prepared using poly[1]ethylene glycol (PEG)-4000, PEG-400, Tween-80, Span-60, distilled water and henna hydroalcoholic extract. Based on the organoleptic character and optimization tests, the final batch was selected. The final batch was evaluated for various physicochemical parameters and antimicrobial activities. Batch containing extract 30%, PEG-4000 37.38%, PEG-400 19%, distilled water 4.55%, Tween-80 and Span 60 4.535% each, passed the disintegration time (11.45 min), mucoadhesiveness (90°) and melting point (37 °C) test and selected as an optimized batch. The mean weight of a suppository was 1.56±0.03 g. Secondary plant metabolites in henna leaves and suppository were comparable. Various molecules identified in leaves were also noted in the suppository on GC-MS. Heavy metals and microbial contamination were within the permissible limit. Zone of inhibition (at 50 µg/mL) and minimum inhibitory concentration for E. coli, S. aureus, S. pyogenes, P. aeruginosa and C. albicans were 20 mm, 18 mm, 20 mm, 16 mm, 19 mm and 20 µg/mL, 10 µg/mL, 25 µg/mL, 25 µg/mL, 45 µg/mL, respectively. This study indicated satisfactory physicochemical parameters and antimicrobial potential of the hydroalcoholic extract-based vaginal suppository of henna. Hence, it may be considered as a better alternative to its traditional dosage form.
Diuretic Effect of the Aqueous Extract of Cymbopogon nardus (L.) Rendle Compared with Furosemide in Wistar Rats
Authors: El Kamari Fatima , Ousaaid Driss , Laaroussi Hassan , Bakour Meryem , Ghouizi Asmae El , Atki Yassine El , Lyoussi Badiaa , Abdellaoui Abdelfattah
Published: April 2023

Cymbopogon nardus (L.) Rendle is one of the medicinal plants widely used in folk medicine to cure certain diseases. The current work aims to assess the diuretic potential of C. nardus using animal models. Urine electrolytes (sodium and potassium), serum electrolytes (sodium, potassium, and chloride), blood urea, creatinine, creatinine clearance, osmolar clearance, urinary osmolarity, and urine ﬂow were determined. To assess the diuretic effect of the studied plant, four groups of rats were used (n = 6). The control group received 10 mL of water, the second and third groups received two doses of the plant (100 and 150 mg/kg bw), and the last group received furosemide (10 mg/kg bw), the experiment sustained for seven days. Urine flow and electrolytes levels were studied. The single dose of C. nardus extract significantly increased urine flow after oral administration. In addition, daily administration of both doses of C. nardus significantly elevated urine excretion, opposite to the first group. C. nardus enhanced the urine elimination of sodium and potassium. Importantly, both doses have no effect on serum potassium level. Creatinine clearance was significantly elevated in a dose-dependent manner. This information will be considered as a keystone for further studies forward in applying new process to isolate active compounds of C. nardus responsible for its biological properties.
Effect of the Hydroalcoholic Extract from the Leafy Stems of Waltheria indica L. (Malvaceae) on Acetylcholine and Barium Chloride-Induced Contractions on Isolated Rat Tracheal Tissue
Authors: Zakaline Yabré , Rainatou Boly , Mathieu Nitiéma , Lazare Belemnaba , Hoho Estelle Youl Noëla , Innocent Pierre Guissou , Sylvin Ouédraogo
Published: April 2023

A previous study has reported the interesting relaxant effect of the hydroalcoholic extract from Waltheria indica L. (Malvaceae) leafy stems, a plant with several therapeutic uses. The present study aimed to investigate the preventive effect of this plant using an ex vivo model of the rat trachea. Two agonists, acetylcholine (10-6 - 1.5×10-5 M) and barium chloride (10-5- 10-1 M) were used to induce contractions. The preventive effect was assessed on rat tracheal rings pretreated with hydroalcoholic extract (1.92 mg/mL), glibenclamide, atropine, and papaverine, all at 10 µM. Acetylcholine and barium chloride provoke contractions in a concentration-dependent manner, with a maximum contractile response of 3.953 ± 0.692 g and 2.999 ± 0.326 g, respectively. The EC50 values were 3.711 ± 0.823 µM and 9.502 ± 12.354 mM, respectively, for acetylcholine- and barium chloride-induced contraction. Glibenclamide caused a rightward shift of the acetylcholine-response curve, followed by a reduction of the maximum contraction (from 3.953 ± 0.692 g to 3. 116 ± 0.244 g). The hydroalcoholic extract, atropine, papaverine, and their combinations induced a complete suppression of the contractile response to acetylcholine (p < 0.0001) and barium chloride (p < 0.0001). The hydroalcoholic extract exhibited a potent relaxant effect comparable to that of atropine and papaverine. It can be concluded that the hydroalcoholic extract of W. indica can potently prevent acetylcholine-and barium chloride-induced contractions. The possible mechanisms by which the extract exerts its relaxant effect may involve the blockade of muscarinic receptors, the inhibition of phosphodiesterase activity, and/or the calcium channel.
Comparison of Horse and Cow Milk on the Symptoms of Attention Deficit Hyperactivity Disorder in Children: A Cross-Over Clinical Trial Study
Authors: Jokar Seyedeh Zahra , Sadeghieh Tahereh , Shakiba Mehrdad , Emtiazy Majid , Sadeghmanesh Ruhollah , Hashemi Monire Seyed , Mousavi Zohreh
Published: April 2023

Numerous researchers have examined the effect of diet on Attention Deficit Hyperactivity Disorder (ADHD). The purpose of this study is to compare the symptoms of ADHD in children fed horse milk versus conventionally fed cow's milk. Thirty patients aged 6 to 14 with ADHD were randomly selected and divided into two groups in this randomized double-blind crossover study. All patients completed a 45-day period of consuming 250 mL horse or cow milk, as well as continued Ritalin (1 mg/kg) treatment. The wash out period was considered one week. Symptoms are recorded using the Conners rating scale (CS). The CS of the parents decreased significantly (P value≤0.001) in the group that first received horse milk, but increased (P value=0.007) after consuming cow's milk. After consumption of horse milk, the parent's CS was significantly different from that of cow milk (P value= 0.001). Teachers' CS decreased significantly following horse milk consumption (P=0.001) and increased significantly following cow milk consumption (P=0.028) in this group. The average teacher's CS after cow milk differed significantly from that after horse milk (P value= 0.024). The CS of the parents did not change significantly (P value=0.913) in the group that first consumed cow's milk. However, it was significantly decreased (P value=0.004) after receiving horse milk. The CS of the teachers in this group did not change after the cow's milk (P value=0.282). However, following the administration of horse milk, the mean of CS decreased significantly (P=0.003). The average of the teacher's CS after consuming cow milk differed significantly from that of horse milk (P value= 0.010). In both groups, there was no significant difference in the mean of parents and teachers CS before and after the washout period (P>0.05). According to the study, horse milk consumption was significantly more effective than cow milk at lowering scores.
Ethnopharmacological Survey of Medicinal Plants Used in the Management of Skin-Related Conditions in Ilorin, North-Central, Nigeria
Authors: Falana Mansurat B. , Nurudeen Quadri O. , Salimon Saoban S. , Abubakar Ibrahim B.
Published: April 2023

The abundance of plants with medicinal values has been of great impact on the skincare industry in Nigeria.  However, proper documentation of plants with skincare values has not been made. Hence, this study was aimed at surveying the traditional medicinal values of some commonly used plants for the management of skin conditions by herbal practitioners in Ilorin metropolis. Ethnobotanical and demographic information of willing respondents were obtained on the most commonly used medicinal plants via semi-structured questionnaires and oral interviews. The names of the plants were further confirmed in the world flora online (www.worldfloraonline.org). A total of 57 plants species representing 30 families, were reported by 62 respondents including males (40%) and females (60%) designated as herbs sellers (32%), traditional medicine practitioners (16%), farmers (8%), and housewives (11 %). Their knowledge sources include inheritance (40%), training (24 %), and a combination of inheritance and training (36%). Euphorbiaceae was the most cited (11 %) plant family, the leaves were the most cited (48%) plant part used, crush to extract juice was the most widely used (51%) method of preparation, and topical application on the affected spot was the most reported (43%) method of administration. The plants mentioned in this survey were reported to have applications against psoriasis, eczema, boils, acne, measles, dandruff, rashes, and wounds. General skin conditions represented the most commonly mentioned (14%) skin condition; while mastitis was the least mentioned (1%) condition.  Also, the highest (0.923) informant consensus factor (ICF) was mentioned for insect bites; while the least (0.263) ICF was mentioned for general skin conditions. This study documented some of the medicinal plants that have been used to treat various skin-related conditions most of which have been mentioned in available scientific pieces of literature.
Brain Structural Response and Neurobehavioral Changes in the Elderly after Tai Chi Practice - A Literature Review
Authors: Liu Howe , Salem Yasser , Arguello Eric , Liu Hao
Published: April 2023

Tai Chi (TC) has been often provided to older adults by rehabilitation professionals for medical dysfunction and anti-aging healthcare. In last decade, there has been an increase in the number of studies examining the effects of TC on brain as assessed by neuroimaging including near infrared spectroscopy (fNIRS), and structure and functional magnetic resonating imaging (sMRI & fMRI). Thus, the primary purpose of this literature review is to evaluate how TC practice may affect the brain in the elderly as assessed by neuroimaging techniques, and followed by corresponding neurobehavioral changes as the secondary purpose. A comprehensive literature search was conducted using a variety of keywords with different search engines to search from the last ten years until January 15, 2022. Studies were included if they investigated topographic brain responses after TC practice in the elderly population. A total of 12 original studies with 15 articles met the criteria and were included for the review process. The results showed increased volume of cortical grey matter, improved neural activity and homogeneity, and increased neural connectivity in different brain regions, including the frontal, temporal, and occipital lobes, cerebellum, and thalamus. Intriguingly, the longer one practices TC, the more his/her brain regions may be altered. Such neural findings after TC practice are often associated with neurobehavioral improvements in attention, cognitive execution, memory, emotion, and risk-taking behaviors. TC is a promising exercise that is able to improve structural capability and neurofunctional activity in the brain in the elderly. These improvements appear to be associated with the time-length of TC practice.
Study the Relationship Physiology and Molecular Biology in Patients of Iraq Drug Use Parameters Acute Leukaemia (AL)
Authors: Ismail Ibrahim Bushra , Hatem Abdulwahhab Hayder
Published: April 2023

Study of paper is physiology use to analysis total  in LDH is an intracellular enzyme whose activity is associated with cellular metabolism, WBCs count in blood to patients which makes it a marker of cell proliferation and cell injury and study with molecular biology of marker parameters use drug the presence of survivin in neoplastic cells contributes to tumor development and its high transcription has been reported as a predictor of poor prognosis in several hematological malignancies. However, despite being frequently present in ALs, the impact of survivin transcription in this type of hematologic malignancy remains undefined. Some studies report that survivin predicts an unfavorable clinical outcome in ALs, while others do not. In the present study, despite the small number of patients evaluated, the transcription of survivin at diagnosis did not seem to be related to a worse response to treatment or a worse prognosis. This is because, of the six patients who expressed survivin, three are in complete remission and, of the three who died, two were already considered to have an unfavorable prognosis regardless of survivin transcription, one due to advanced age and the presence of leukocytosis in the liver. Leukometry at diagnosis was another prognostic factor evaluated in this study. Patients diagnosed with AL may have elevated, normal, or decreased WBC counts at the time of diagnosis and, in general, counts greater than 30,000 WBCs/mm3 are considered to have a poor prognosis.
Medication Adherence after Myocardial Infarction: The Impact of Anxiety and Depression
Authors: Khalaf Yousef Zubi Arafat , Taye Hasan Al-jarrah Laith , Elbert Alqsous Najib , Wa’el Hindeyeh Mohammad , Rateb Al sarayrah. Yazan
Published: April 2023

Medication Adherence after Myocardial Infarction: The Impact of Anxiety and Depression
LES STRATEGIES ENONCIATIVO-PRAGMATIQUES DANS LE DISCOURS DE JOSEPH KABILA DU 30/06/2016
Authors: SHAMBO OPOKA Damien
Published: April 2023

Face à la nation le 30/06/2016, à l’occasion du cinquante-sixième anniversaire de l’indépendance de la République Démocratique du Congo, le sujet parlant Joseph Kabila fait une communication avec comme objectifs : présenter l’état de la nation, préparer les esprits aux prochaines échéances électorales dont la question principale demeure la définition et le respect des règles de jeu pour éviter les contestations pré et post électorales.

 Pour dénouer ladite question, Joseph Kabila pense à la nécessité d’un forum devant réunir la classe politique, la société civile y comprise, forum de toute attente désignée sous le label de dialogue national inclusif.

Face à ce défi, il importe à Joseph Kabila de mettre en branle l’appareil formel de l’énonciation dans le but d’agir sur son interlocuteur.
The effect of glycemic control on sleep quality in type 2 diabetes mellitus
Authors: KOÇ Zeynep , BÖYÜK Banu , AKIN Seydahmet , KESKİN Özcan , ALADAĞ Nazire
Published: April 2023

Objectives: There are publications showing sleep quality is impacted in type 2 diabetes mellitus (T2DM) cases. In our study, we planned to assess the prevalence of sleep disorder in these patients compared to society, and investigate whether poor glycemic regulation and increased body mass index (BMI) caused disruption of sleep quality or not. Methods: Sleep quality was compared between patients followed in our clinic with T2DM (n = 534) for minimum 5 years and a control group (n = 269). Assessment was performed for whether increased glycated haemoglobin (HbA1c) and increased BMI caused an increase in Pittsburgh Sleep Quality Index (PSQI) score or not. Cases with any comorbid disease or drug use affecting sleep quality were excluded from the study. Results: T2DM patients had higher PSQI points compared to the control group. A statistically significant, very low-level positive correlation was identified between BMI measurements and PSQI scores (as BMI increased, PSQI increased). A statistically significant, very low-level positive correlation was identified between HbA1c measurements and PSQI scores (as HbA1c increased, PSQI increased). HbA1c measurements of those in the good sleep quality group were significantly lower compared to those in the moderate sleep quality and poor sleep quality groups. The BMI measurements in the poor sleep quality group were significantly higher than those in the good sleep quality group. Conclusions: The sleep quality of T2DM cases was worse compared to the control group, while the increase in HbA1c level further disrupted sleep quality. The increase in BMI is another factor disrupting sleep quality in diabetic patients.
ТЕХНОЛОГИИ КОНСТРУИРОВАНИЯ ОБРАЗОВ БУДУЩЕГО: КУЛЬТУР-ФИЛОСОФСКИЙ АНАЛИЗ (В ПЕЧАТИ)
Authors: Лукьянова Наталия Александровна , Семерник Снежана Здиславовна , Охотницкая Екатерина Мечиславовна
Published: April 2023

В данной статье анализируется проблема построения образов будущего на уровне индивидуального и общественного сознания. Обосновывается положение о том, что образы будущего зависят от множества факторов, имманентно присутствующих в социокультурной реальности. Они детерминированы коллективным пониманием исторического прошлого, типом господствующей картины мира (мифологической, религиозной, научной), влияют на перспективы развития общества и поведение людей в настоящем. Авторы обращают внимание на значение модуса образа будущего – положительного или негативного. Положительный образ будущего способствует прогрессивно-восходящему развитию социума, негативный образ будущего порождает пессимизм общественного сознания, апокалипсичность мировосприятия. Актуальность предлагаемого исследования обусловлена спецификой развития современного социума. Эскалация перемен, нарастание неопределенности и рисков развития социума актуализирует проблему определения перспектив его развития. Образ будущего как целостное представление о возможностях общества в ближайшем и отдаленном будущем ставит перед исследователями задачу изучения данного образа, определения оптимальных технологий его конструирования, соответствующих потребностям современного общества. В соответствии с этим заявлена следующая цель статьи – раскрыть значение концепта «образ будущего» при определении перспектив развития социума и культуры, выявить адекватные современной действительности технологии его конструирования. Методы исследования: анализ, синтез и теоретическое обобщение. В статье последовательно анализируются идеи ученых о содержании концепта «образ будущего», рассматриваются важнейшие технологии конструирования будущего. Обосновывается идея о том, что в современных прогностических исследованиях осуществлен переход от линейных к нелинейным стратегиям понимания будущего и делается акцент на технологиях конструирования будущего, комплементарных нелинейному пониманию динамики современного социума и культуры. Результаты. Доказывается, что от линейно-отражательной концепции понимания образа будущего современная наука переходит к нелинейно-конструкторской его интерпретации. Важнейшими технологиями конструирования будущего выступают планирование и проектирование, подчеркивающие роль субъективного фактора в осуществлении перспективных возможностей будущего.
Öğretmenlerin Örgütsel Mutlukları ile Örgütsel Bağlılıklarının İncelenmesi
Authors: KARADAŞ Halil , AKIN Mehmet Ali
Published: April 2023

Bu araştırmada öğretmenlerin örgütsel mutluluk ve örgütsel bağlılıkları arasındaki ilişki düzeyinin ve öğretmenlerin örgütsel mutluluk ve örgüt bağlılık algılarının bağımsız değişkenlere göre farklılaşma durumlarının incelenmesi amaçlanmıştır. Araştırma Çalışma 1 (nicel) ve Çalışma 2 (nitel) şeklinde iki aşamalı olarak yapılarak, bu kapsamda karma desen tercih edilmiştir. Araştırmanın verileri Mardin Artuklu ilçesindeki eğitim paydaşlarından toplanmıştır. Çalışma 1 kapsamında öncelikle nicel araştırma yöntemleri ile öğretmenlerin örgütsel mutluluk ve örgütsel bağlılık algı düzeyleri incelenmiştir. Çalışma 2 kapsamında yapılan nitel araştırma ile örgütsel mutluluk ve örgütsel bağlılık algı düzeyine ilişkin durumlar derinlemesine incelenmeye çalışılmıştır. Bunun için araştırmaya katılmaya gönüllü olan ve öğretmenler ile okul yöneticilerinden oluşan 30 katılımcı ile görüşmeler yapılmıştır. Araştırmanın birinci aşamasında yapılan nicel çalışma sonucunda öğretmenlerin örgütsel mutluluk ve örgütsel bağlılık algılarının cinsiyet ve eğitim düzeyi değişkenine göre anlamlı düzeyde farklılaşmadığı; buna karşın Görev Yeri ile öğretmenlikteki kıdem değişkenine göre farklılaştığı sonucuna ulaşılmıştır. Diğer yandan yapılan nitel araştırmada ise öğretmenlerin mesleğe ilişkin mutlu olmalarını sağlayan durumların okulda aile ortamının tesis edilmesi, öğretmenlik mesleğini severek yapma, okulun fiziki imkânların yeterli olması, sınıf mevcutlarının çok fazla olmaması ve okuldaki paydaşlarla olan pozitif iletişim kurulması şeklinde ortaya çıkmıştır. Öğretmenlerin bağlılık algı düzeylerine ilişkin olarak okulun maddi imkânlarının yetersiz olması, velilerin ilgisizliği, sınıf mevcutlarının çok kalabalık olması, okulun fiziki, sosyal ve kültürel şartlarının yetersiz olması, çocuklarda davranış bozukluklarının olması ve okulun yeterince temiz olmaması şeklinde sonuçlara ulaşılmıştır. Araştırmanın iki safhasında ulaşılan sonuçların sentezlenmesiyle çeşitli önerilerde bulunulmuştur.
Different effectiveness of protein fining agents when tested for interaction and precipitation with tannic acid, a seed polyphenol extract and seven wines
Authors: Obreque-Slier Elías , Cortés-Araya Katherine , Medel-Marabolí Marcela , López-Solís Remigio
Published: April 2023

Wine fining comprises any operation resulting in the cleaning, stabilisation and improvement of the organoleptic characteristics of wine. Fining agents, such as certain proteins of varying electrical charges, interact physicochemically with wine polyphenols in ways not yet fully understood with diverse effects on wine attributes. In this study, four widely used protein fining agents (casein, ovalbumin and two gelatins) were compared for their ability to interact with three different types of phenolic-rich solutions: a tannic acid solution, a wine grape seed extract and seven different varietal wines. A phenolic characterisation of both the seed extract and all the wines was carried out. The interaction between the protein fining agents and the phenolic solutions was evaluated by diffusion and precipitation tests on cellulose membranes and protein staining. All four protein fining agents interacted to differing extents by producing soluble and insoluble complexes with the tannic acid, grape seed extract and wines. In the wines, the interactions were found to not only depend highly on the protein composition of the fining agent, but also on the chemical composition of the wine. Notwithstanding, the observed phenolic differences between the wines could not fully account for the differential interactions between wine and the fining agents, thus indicating that the wine matrix as a whole may play a role in those interactions.
THE RELATIONSHIP OF FIXED ASSET REVALUATION TO PERCEPTION OF PERFORMANCE: EVALUATION OF TAX POLICY
Authors:   Pusat Pembinaan Profesi Keuangan, Jakarta, Darmawan Andi , Ramona Sinaga Andar ,   Pusat Pembinaan Profesi Keuangan, Jakarta, Wibowo Arie ,   Pusat Pembinaan Profesi Keuangan, Jakarta
Published: April 2023

This study aimed to know the relationship between fixed asset revaluation and the perception of the company's performance in the future. This research can advise the government on the effect of fixed asset revaluation on company performance when the government repeats the policy of reducing fixed asset revaluation taxes during the economic recovery during the pandemic. The methodology used in this study was mixed methods research, which collected and analyzed qualitative and quantitative data. This research used primary data from focus group discussions (representatives of industrial entities, tax consulting practitioners, public accountants, regulators, and related authorities) and questionnaires distributed to 118 listed companies. This research found that implementing fixed asset revaluation in the company has an effect on increasing the company's performance perception in terms of accounting-based measures but did not necessarily increase the company's performance perception in terms of market-based measures. This research also explored the company's motives for revaluing fixed assets and the factors that became obstacles to implementing the fixed-asset revaluation tax incentive policy in Indonesia, including recommendations for implementing the fixed asset revaluation tax policy in the future.
Apakah Jenjang Pendidikan Dasar Tenaga Kerja Berperan dalam Mengurangi Kemiskinan di Indonesia?
Authors:   Sekolah Tinggi Ilmu Statistik – Badan Pusat Statistik, Rizal Rofiq Nur
Published: April 2023

Meningkatkan kualitas sumber daya manusia melalui pendidikan diyakini sebagai salah satu solusi untuk mengurangi kemiskinan. Kepedulian dunia internasional terhadap pendidikan dalam gerakan global ’Pendidikan Untuk Semua’ dan ’Tujuan Pembangunan Milenium’, menegaskan bahwa pendidikan dasar menjadi pusat untuk mengurangi kemiskinan. Ketika terdapat hubungan linier antara pendidikan dan pendapatan, maka meningkatkan pendidikan hanya pada tingkat pendidikan dasar tidak akan meningkatkan pendapatan secara substansial. Studi ini bertujuan untuk menganalisis peran jenjang pendidikan tenaga kerja terhadap kemiskinan. Menggunakan data panel, studi ini menunjukkan bahwa secara signifikan jenjang pendidikan dasar tenaga kerja berperan meningkatkan kemiskinan, sedangkan tenaga kerja dengan jenjang pendidikan lebih tinggi signifikan mengurangi kemiskinan di Indonesia.
Pola Permintaan Daging Tingkat Rumah Tangga di Indonesia: Analisa Data Mikro 2013
Authors:   Magister Perencanaan dan Kebijakan Publik, Fakultas Ekonomi dan Bisnis Universitas Indonesia, Nugroho Sigit , Suparyono Sita Wardhani ,   Departemen Ilmu Ekonomi, Fakultas Ekonomi dan Bisnis Universitas Indonesia
Published: April 2023

Tujuan penelitian ini adalah untuk mempelajari pola permintaan daging di Indonesia. Penelitian ini menggunakan data survei rumah tangga SUSENAS 2013 dan Sensus Pertanian 2013 yang dikeluarkan oleh Badan Pusat Statistik. Penelitian ini menggunakan pendekatan Quadratic Almost Ideal Demand System (QUAIDS) dengan estimator Iterated Linear Least Square (ILLS). Hasil analisis menunjukkan bahwa terdapat pengaruh kota, pendidikan, ukuran rumah tangga, kelas pendapatan, dan suplai daging domestik terhadap pola permintaan dan elastisitas daging.
Pengaruh Pemasaran pada Media Sosial dan Ulasan Pelanggan Online Terhadap Niat Beli Dimediasi oleh Kepercayaan Pelanggan: Studi Pada Pengikut Media Sosial Produk Kosmetik di Wilayah Jakarta
Authors: Fahrani Vannisa , Usman Osly , Aditya Shandy
Published: April 2023

The purpose of this research is to investigate the effect of social media marketing on customer trust, online customer review on customer trust, social media marketing on purchase intention, online customer review on purchase intention and customer trust on purchase intention of Scarlett Whitening's social media followers in the Jakarta area. The research data was collected by distributing questionnaires to Scarlett Whitening's social media followers and the sample of this study was 245 respondents. Researchers used Lisrel version 8.8 as a SEM application to process and analyze research data. The results of the study show a positive and significant influence between Social Media Marketing on Customer Trust, Online Customer Reviews have a significant effect on Customer Trust, Social Media Marketing has a significant effect on Purchase Intention, Online Customer Reviews have a significant influence on Purchase Intention, and Customer Trust has a significant effect on Purchase Intention to Scarlett Whitening online store.

 

Tujuan dari penelitian ini adalah untuk melihat pengaruh social media marketing terhadap customer trust, online customer review terhadap customer trust, social media marketingterhadap purchase intention, online customer review terhadap purchase intention serta customer trust terhadap purchase intention pada pengikut sosial media Scarlett Whitening di wilayah Jakarta. Data penelitian dikumpulkan dengan penyebaran kuesioner kepada pengikut sosial media Scarlett Whitening dan sampel penelitian ini ialah sebanyak 245 responden. Peneliti menggunakan Lisrel versi 8.8 sebagai aplikasi SEM untuk mengolah dan menganalisis data penelitian. Hasil dari penelitian menunjukkan pengaruh positif dan signifikan antara Social Media Marketing terhadap Customer Trust, Online Customer Review berpengaruh signifikan terhadap Customer Trust, Social Media Marketing berpengaruh signifikan pada Purchase Intention, Online Review Customer memiliki pengaruh signifikan pada Purchase Intention, serta Customer Trust berpengaruh signifikan pada Purchase Intention terhadap toko online Scarlett Whitening.
Pengaruh Gamification dalam Membentuk Brand Loyalty melalui Brand Engagement
Authors: Wulandari Novita Ayu , Saidani Basrah , P Agung Kresnamurti Rivai
Published: April 2023

This study aims to find the effect of gamification on brand loyalty with brand engagement as an intervening variable. The study starts at Mei 20201 until Augustus 2021 using an online questionnaire. Chosen by purposive sampling technique, the respondents are 200 marketplace users in Jabodetabek who had used the gamification feature on e-commerce ‘s’ and had shopped using the rewards. An analysis method that using in this study is Structural Equation Modelling (SEM) using SPSS version 28 and AMOS version 26. It showed that gamification had a significant and positive effect on brand engagement, gamification had a significant and positive effect on brand loyalty, brand engagement had no significant and positive effect on brand loyalty, and gamification had no significant and positive effect on brand loyalty through brand engagement as intervening.

 

Penelitian ini bertujuan untuk mengetahui pengaruh yang dimiliki gamification dalam membentuk brand loyalty melalui brand engagement sebagai variabel intervening. Penelitian dimulai sejak Mei 2021 sampai dengan Agustus 2021 dengan menggunakan kuesioner yang dibagikan secara online. Menggunakan dengan teknik purposive sampling, responden dalam penelitian ini merupakan 200 orang pengguna e-commerce di daerah Jabodetabek yang menggunakan fitur gamifikasi di e-commerce ‘s’ dan pernah berbelanja menggunakan reward dari gamification tersebut. Metode analisis yang digunakan adalah Structural Equation Model (SEM) dengan alat bantu perangkat lunak SPSS versi 28 dan AMOS versi 26. Hasil dalam penelitian ini menunjukkan bahwa gamification memiliki pengaruh signifikan dan positif terhadap brand engagement, gamification memiliki pengaruh signifikan dan positif terhadap brand loyalty, brand engagement tidak memiliki pengaruh signifikan dan positif terhadap brand loyalty, dan gamification tidak memiliki pengaruh signifikan dan positif terhadap brand loyalty dengan brand engagement sebagai variabel intervening.
Analisis Faktor-Faktor Visit Intention Pulau Morotai selama Pandemi COVID-19
Authors: Hanipah  , Nuraini Shafira , Citra Chika Dwy , Kamil Bagas Fiqri , Suhud Usep
Published: April 2023

This study examines the factors that influence the intention to visit Morotai Island during the COVID-19 pandemic. There are six variables used to measure, namely country image, destination image, travel motivation, tourist satisfaction, electronic word of mouth (E-WoM), and visit intention. For this reason, we use the research method of distributing questionnaires with the population in the study being people in Jakarta and using a sample of respondents who have the intention to visit Morotai Island with a vulnerable age of 25 years or more and involving 217 respondents who participated in filling out the questionnaire. The data is processed using exploratory factor analysis and a structural equation model. The result is that E-WoM affects the destination image.

 

Penelitian ini mengkaji factor-faktor yang mempengaruhi niat berkunjung ke Pulau Morotai selama pandemic COVID-19. Ada enam variabel yang digunakan untuk mengukur, yaitu country image, destination image, travel motivation, tourist satisfaction, electronic word of mouth (E-WoM) dan visit intention. Untuk itu kami menggunakan metode penelitian menyebar kuesioner dengan populasi dalam penelitian ialah masyarakat di Jakarta dan menggunakan sampel responden yang memiliki niat untuk mengunjungi Pulau Morotai dengan rentan usia 25 tahun atau lebih dan mwlibatkan 217 responden yang ikut berpartisipasi mengisi kuesioner. Data diolah menggunakan explaratory factor analysis dan structural equation model. Hasilnya E-WoM mempengaruhi destination image.