bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and approbation of an analytical method for the quantitative determination of carbon tetrachloride in freons used in the composition of medicines in the form of an aerosol
Authors: Selyutin Oleg A. , Shatalov Denis O. , Pisarev Dmitry I. , Novikov Oleg O. , Zhilyakova Elena T. , Chichulina Victoriya V.
Published: March 2023

Aim to develop and test an analytical method for the quantitative determination of carbon tetrachloride in freons used in the composition of medicines in the form of an aerosol.
Material and methods. Carbon tetrachloride (tetrachloromethane, Freon-10) - CCl4, M.m. = 153.81, heavy, colorless, volatile liquid with a sweet smell reminiscent of chloroform. Melting point - 22.96 С, boiling point - 76.75 C, relative density at 20 - [d]420 1.595. Poorly soluble in water (0.5 g/l), unrestrictedly miscible with alcohol, ether, acetone, benzene (chemically pure grade).
To determine the tests for the presence and quantitative determination of carbon tetrachloride in propellant gases used in medicinal preparations, we chose the drug "Salbutamol-Pharmstandard". To identify and quantify carbon tetrachloride in propellants used in medicinal products, the gas-liquid chromatography method with electron capture detection with a capillary column was applied.
Results. The developed method was used to determine carbon tetrachloride in the test preparation "Salbutamol". The results were statistically processed and showed that the content of carbon tetrachloride in the test preparation was 0.01580.0007 mg/l. The error of a single experiment with a confidence probability P = 95% was 4.42%
Conclusion. We proposed a method for estimating the content of carbon tetrachloride impurities in aerosol dosage forms by gas-liquid chromatography with an electron capture detector. The technique involved the gas chromatographic separation of a sample, taken from an aerosol can, on a capillary chromatographic column. The most appropriate detector in this case turned out to be an electron capture detector.
Knowledge-Building Environments
Authors: Leblanc Tatjana , Giroux Sylvain , Teuwen Marilyne
Published: March 2023

Despite the innovative features that many sophisticated products offer, they seem to have created new challenges instead of simplifying people’s lives. Neophytes or people with cognitive deficiencies, for example, seem particularly uneasy when facing complex user interfaces. Designing for people involves getting to know the user and his perception of the environment of use, which necessitates a broader perspective and extended knowledgebase. The paper will discuss how design education attempts to address the need for teaching interdisciplinary skills and systemic thinking. A case study will illustrate an experimental teaching framework and the implementation of an interdisciplinary learning environment that merges researchers, graduate and undergraduate students from different disciplines in a joint project. The paper will conclude with an assessment of this teaching experience and offer recommendations for future consideration.
Project-Based Learning applied to a Master in HCI
Authors: Granollers Toni , Oliva Marta , Garcia Roberto , Gil Rosa
Published: March 2023

In this paper, we describe the experience of starting the first HCI master in Spanish language for the wide Spanish speaking context held in the University of Lleida (Catalonia). It combines the semi-distance educational paradigm with the Project-Based Learning educational methodology. The paper also describes how this first experience has reached from previous HCI teaching experiences and how all the subjects has been restructured in order to offer a complete HCI program for the Spanish speaking students.
Business-driven assignment for teaching HCI
Authors: Sas Corina , Dix Alan
Published: March 2023

The purpose of this paper is to offer a reflection on some of the challenges of teaching interaction design. A proposed solution to address these challenges is through a business- driven problem which has been translated into a research question to be tackled by students in their learning context. The case study outlines and evaluates the six stages of this process. Apart from providing the company with research solutions that can be used to improve its profitability, other benefits consist of better teaching/learning process which emphasises learning by doing and involves applying research knowledge and skills in an industrial project. The paper also highlights the lessons learned and the understanding gained into how this approach can be successfully replicated.
Interacting With Urbanity
Authors: Mellbratt Anders , Wiberg Nils
Published: March 2023

This project has explored means of interaction between creators and recipients of mediated culture within the realm of architectural space through the use of video.
Towards a Dialogue Based Interface for Query Synchronization
Authors: Polese Giuseppe , Vacca Mario
Published: March 2023

The query synchronization is one of main issues of schema evolution: when a schema evolves the existing queries could stop working and it becomes necessary to redefine them over the new schema. In this paper, according to the recently recognized importance of advanced query formulation inter- faces, the basic ideas and components underlying an inter- active model of tool for supporting query synchronization are outlined.
The LUA Toolbar
Authors: Ceipidor Ugo Biader , Medaglia Carlo Maria , Sciarretta Eliseo
Published: March 2023

In this paper we describe a new toolbar for the validation of website accessibility. This issue concerns the right of all citizens to obtain and maintain access to a society-wide pool of information resources and interpersonal communication facilities. At first we speak about the needs of impaired users for a profitable Web navigation. In the second section the focus is on the Italian “Stanca Act”, which defines the primary environment of the project; then we explain the toolbar most valued features: the ease of use of its interface and the precision of responses gathered. Finally we show our interface prototype with its major options and, in the last section, we picture the further development.
Towards a Socially Intelligent ECA
Authors: Carofiglio Valeria , De Carolis Berardina , Mazzotta Irene , Novielli Nicole , Pizzutilo Sebastiano
Published: March 2023

Embedding the HCI technology with human preferences and behaviour justifies the attempt of implementing emotional and social intelligence aimed at exceeding the single ability to help the user. In this paper we present an Embodied Conversational Agent’s (ECA’s) architecture and methods useful to interpret the user affective attitude during her dialog with an ECA and behaving ‘believably’in its turn. In particular, we present an agent architecture that is general enough to be applied in several application domains and that can employ several ECA’s bodies according to the context requirements.
Effect of drip irrigation on richness, abundance and diversity of soil arthropods
Authors: Sajjad Asif
Published: March 2023

Arthropods maintain soil ecosystem in variety of ways like breaking down the plant debris and broadcasting the microorganisms. The human induced changes in the agricultural land (i.e., irrigation methods, tillage practices and land use changes) have profound impacts on the richness, diversity and abundance of arthropods. The present study was carried out to assess the effect of drip irrigation on the richness, abundance and diversity of soil arthropods at three different Tehsils of District Bahawalpur i.e.  Bahawalpur, Khairpur and Ahmedpur East.  At each location, one flood and one drip irrigated guava orchard was selected. Weekly data of soil arthropods was recorded using 10 pitfall traps (at least 50 feet apart) in each orchard during April and May, 2022. The species richness, abundance, dominance and evenness of soil arthropods were slightly higher in flood irrigation orchards. However, Simpson, Shannon-wiener and chao-1 diversity indices did not vary significantly. Rank abundance curves showed that in all the drip and flood irrigated orchards, there was still some possibility of finding new species with the increasing sample size. Only one ant species Camponotus compressus (Hymenoptera: Formicidae) constituted the major proportion of arthropods abundance in all the orchards whereas most of the species were very low in abundance. The results suggest that the soil arthropod diversity is not significantly affected with the flood and drip irrigation methods. Therefore, keeping in view the proven economic and water conservation advantages, the drip irrigation system can be adopted without harming soil arthropods diversity.
Efficacy of Biocontrol Agent (BCA) Trichoderma spp. Against Black Scurf Disease (Rhizoctonia solani) of Potato
Authors: Huma Zill e
Published: March 2023

The current study was designed to determine the efficacy of Trichoderma against soil borne pathogen Rhizoctonia solani causing Black scurf disease in potato. Five various species of Trichoderma (Trichoderma herzianum, Trichoderma asperellum, Trichoderma viride, Trichoderma hamatum and Trichoderma helicum) were screened in vitro against Rhizoctonia solani via Dual culture technique. Amongst the antagonists Trichoderma herzianum, Trichoderma viride and Trichoderma helicum was found to be more potent in inhibiting the mycelial growth of Rhizoctonia solani. The results indicate that Trichoderma helicum and Trichoderma viride showed significant growth in suppressing the mycelial growth of Rhizoctonia solani thus a highest inhibition percentage  71.8% was attained  however, the  Trichoderma herzianum, Trichoderma asperellum  and  Trichoderma hamatum  showed mycelial percentage of  71.45%, 68.2% and 64.5% respectively. It is therefore concluded that an insignificant inhibition percentage 64.5% was shown by Trichoderma hamatum and found to be least effective  in reducing mycelial growth as well as sclerotia formation of the test pathogen Rhizoctonia solani. However Trichoderma is good biocontrol agent and therefore can be used against Black scurf disease of potato.
Impact of Salt stress on Morphology and Physiology of Maize Plants
Authors: Ahmad Zohaib
Published: March 2023

Soil salinization negatively influences crop plants worldwide. Stress conditions can defer plant development and improvement, lessen productivity, and in outrageous cases cause plant death. The biomass, morphology, homeostasis, and functioning of the plant are reduced under the influence of salt stress. High rates of the salts inside the plant tissues are toxic metabolically and can lead to a reduction in root and shoot weight, oxidative stress, production of ROS, and inhibition of photosynthesis. Maize is an important fodder crop grown worldwide. Nutritional imbalance, reduced seed germination, vegetative growth, and uptake of the nutrients have been noticed in maize crops as a result of salt accumulation. Seedling vigor, development, and stress resistance ability of the maize crop have been improved by nutritional management and an effective, simple, and receptive way known as seed priming. Soaking of seeds in water before sowing, i.e. hydropriming and use of different chemicals, i.e. osmopriming is being practiced in this regard. These seed priming methods facilitate the treated plants with resistance against salinity, early growth, vigorous plant stand, and uniform germination. So, this review paper investigates the effect of salinity on maize crops and the efficacy of osmo and hydro priming methods against abiotic stresses, especially soil salinization.
Botanical investigation of goats pastures on natural and replanted grasslands
Authors: Stilling Ferenc , Poti Peter , Pajor Ferenc , Hajnaczki Sandor
Published: March 2023

There are new challenges for global agriculture due to the changing circumstances in natural and economical world. Many professionals mentioned that our current agricultural methods not suitable to produce proper amount and quality foods. We have to change from the conventional farming to a sustainable agriculture to reach a well performing global agriculture what consist local viable agro systems. The organic farming as one type of sustainable agriculture, is a developing sector where the market and economical competition is growing. There is an opportunity to produce high quality food without additives in Hungary based on the climate, good quality soil as well traditional plant and animal species. The hungarian government set better balance between animal husbandry and arable farming as target and focusing on family farming and organic farming.
Vegetation investigation of cattle pastures in the Ipoly Valley, Dejtár
Authors: Turcsanyi-Jardi Ildiko , Penksza Karoly , Salata-Falusi Eszter
Published: March 2023

The most natural and appropriate way to preserve the biodiversity of grasslands is the utilization, which is confirmed by current research. Conservation management requires intensive cooperation between nature conservation and intensive grassland utilization. Therefore, we investigated the effect of extensive grassland utilization on the outskirts of Dejtár.
Navigating early Chinese daybook divination manuals
Authors: Foster Christopher J.
Published: March 2023

In Early China, ‘daybook’ (rishu 日書) divination manuals were consulted to determine auspicious times for a variety of life events. Recent discoveries of daybook manuscripts written upon bound bamboo strips have revealed much about how these manuals were compiled in the first centuries BC. Multiple different divination systems appear on the same manuscript, resulting in a confusion of running text, lists, and diagrams. In order to navigate these manuscripts efficiently, daybook compilers utilized certain strategies to aid their users. Taking the Han period Zhoujiazhai 周家寨 daybook as a case study, this article surveys the strategies employed in this manuscript to differentiate textual units. Attention is given to the materiality of the writing support, judicious framing with empty space, features of the calligraphy, punctuation usage, indexing, and the presence of both explicit titles and embedded identifiers.
Reading Ancient Maya Hieroglyphic Books
Authors: Prager Christian
Published: March 2023

Spanish priests burned hundreds of images of idols, cult objects, and manuscripts with Mayan hieroglyphs following the conquest of the Yucatan Peninsula, convinced that this would encourage the indigenous population to renounce their ancient beliefs and turn to the Christian God. In so doing they destroyed the memory of a written culture that had existed for over two thousand years. Only four Maya manuscripts—the so-called codices—survived this missionary zeal and the tropical climate of the Yucatan, and these are today kept in museums and libraries in Mexico City, Madrid, Paris, and Dresden. Unlike hieroglyphic texts on stone monuments they do not relay historical events, but instead are mainly divinatory and related to the 260-day Tzolk’in calendar, holding predictive information about the success or failure of everyday activities on favourable or unfavourable days. The author uses a farmers’ almanac from the Dresden Codex to explain the function of Maya calendars, to discuss the significance of time, and to reconstruct how Mayan calendar priests would read daily predictions in the correlated images and texts and apply them to daily practice.
The Karlevi runestone
Authors: O'Donoghue Heather
Published: March 2023

The Karlevi runestone, on the island of Öland, off the south-east coast of Sweden, is inscribed with the only known full stanza of Old Norse skaldic verse in Viking Age runes (that is, from approximately AD 750–1100). It is generally dated to the end of the tenth century, making it the oldest existing record of such verse. This piece outlines the origins, distribution, and chief features of the runic alphabet; contextualizes the inscription on the Karlevi runestone and the location of the stone itself; analyses the lettering and layout of the inscription in relation to the metre, style and cultural context of the verse it holds; and finally describes the character of skaldic verse and interprets the stanza.
Trilingual sales contract on papyrus from Roman Arabia (P.Yadin I 22)
Authors: Zellmann-Rohrer Michael
Published: March 2023

This contribution considers the context, textual content, and means of textual division in a trilingual sales contract from Roman Arabia. The text, P.Yadin I 22, formed part of the so-called Babatha archive, the family papers of a Jewish woman who later took refuge in the Judaean Desert, where the documents were later discovered. Despite the absence of formal punctuation marks or word division comparable to modern conventions, the writers of this papyrus used various subtler means to highlight divisions in sense and content, related also to their choices among the three languages at work in the contract (Greek, Nabataean Aramaic, and Jewish Aramaic). This highlighting will have served in the first instance to ease future reference in a document meant to achieve maximum legal precision and authority, but the interplay of languages may also be seen to have ideological implications in the history of the region.
Page Architecture of a Deluxe Arabic Dictionary from Islamic Spain
Authors: Bongianino Umberto
Published: March 2023

The Mukhtaṣar al-ʿAyn of Abū Bakr Muḥammad al-Zubaydī (d. AD 989) is the earliest Arabic dictionary to have survived from the medieval Islamic West. This article discusses an early manuscript of the work that was copied and illuminated in AD 1124, most likely in Valencia, for the library of a wealthy patron or institution. The manuscript’s colophon casts new light on its transmission history, and a close analysis of its ‘page architecture’ reveals both how the book was used and the symbolic and aesthetic functions it fulfilled.
CORPORATE SOCIAL RESPONSIBILITY IN THE OPINION OF MANAGERS OF SMALL AND MEDIUM-SIZED ENTERPRISES IN THE FOOD INDUSTRY FROM THE WARMISKO-MAZURSKIE PROVINCE IN POLAND
Authors: Siemiński Marek
Published: March 2023

The aim of this article is to present the assumptions underlying the corporate social responsibility concept, and to evaluate its perception by managers of small and medium-sized enterprises in the food industry in the Warmisko-Mazurskie Province in Poland. Contemporary managers face the challenges arising from operating in an unpredictable and high volatile environment. Changes are often revolutionary in character, creating completely new conditions for business activities. Corporate social responsibility (CSR) has enriched the world of management with other than economic values. It promotes building a new type of relations with key stakeholders of an organisation. The implementation of actual CSR in an organisation is a difficult, time-consuming and risk-prone process. To a large extent, it depends on the level of awareness of its importance among the managerial staff. The research object consisted of decision-making persons employed in the analysed SMEs. The study was conducted in 2019 and in 2022, using a customised survey. The companies included in the survey focus on internal stakeholders, where the activities undertaken are mostly proactive in character. Regarding external stakeholders, such activities do not typically go beyond the legal norms. Most of the CSR-related activities tend to have an informal character. The importance of socially responsible values according to the surveyed managers working in the food industry is higher than the average value assigned by the sector of small and medium-sized enterprises.
A review of process parameters in friction drilling on joining of steels
Authors: Selvaraj R.M. , Hynes N.R.J.
Published: March 2023

Friction drilling is a unique way of creating holes in steel. In a solitary advance, a rotating conical tool is utilized to enter by penetrating as an opening on the surface of the sheet and making a bushing without making a chip. During this process, the heat produced by the frictional power linking the device and the sheet metal workpiece is used to pierce and make a bushing out of work. The goal of this novel hole-making process is to improve the bushing length in the thin-walled sheet metals by forming a bush and then combining thin sheet metals. The inconceivable utilizations of warm grating penetrating in a few modern areas will introduce another period of interfacing processes for different work materials in automobiles.Researchers have undergone numerous experiments based on the machining parameters, including spindle speed, feed rates, Friction Contact Ratio (FACR), tool angle, tool diameter, sheet thickness, and the output of the friction drilling, includes the bushing length, surface roughness, tool wear, hardness, thrust force, torque and microstructural evaluation.The crucial concerns that should be addressed and researched by researchers in the near future, such as determining the optimal machining parameters of such process and analysing, bushing length, microstructural impacts on the many aspects and their performance, are highlighted.This research paper tends to examine the advancements in research on the friction drilling method and its applications, taking into account the benefits and limits of friction drilling.The present paper identifies the machining parameters and their contribution towards the output level of various materials like Stainless steel, Brass, aluminium, titanium, tempered steel and nickel-based compounds of different thickness.The machining parameters like spindle speeds, feed rate, tool angles, thrust force, Torque, surface roundness, bushing height, frictional heat and tool diameter are optimized in the friction drilling. The incorrect bushing is formed due to the high thrust force, and Low temperatures cause ductility and softening issues.
Preparation and characterization of silicone rubber socket liners modified by nanoparticles additives
Authors: Ameer Z.J.A.
Published: March 2023

The upper part of the prosthesis is called a socket, which contacts the amputated part. While wearing the prosthesis, there are several problems that the patient may suffer from, such as shear force between the socket and amputated part, pressure on the bony prominences, sweating, and bacteria generation, all leading to skin problems and a bad smell. It makes the patient refuse to wear the prosthesis because it is uncomfortable. Therefore, the aim of this study was comfortable lining from silicone rubber which cross-links at room temperature, with properties corresponding to the needs of this application, such as stress distribution, moisture absorption, and antibacterial.In the current work, silicone rubber was selected with the addition of nano-fillers (ZnO, Mg(OH)2, and Chitosan). Mechanical and physical properties were studied (tensile strength, tear strength, hardness, water absorption, porosity, and antibacterial).Chitosan showed the highest effect on the mechanical properties of silicon, as it achieved the highest value of tensile strength of 2.2 MPa elongation of 572%, tear strength 13.9 kN/m, and shore A hardness of 33.3. While the highest value of the modulus, 0.636 MPa was achieved by adding ZnO. The results also showed an increase in the water absorption and the porosity, which were the highest values at 1.6 % and 0.24%, respectively with the addition of Mg(OH)2. The samples showed a clear resistance to preventing the microorganisms growth.Manufactured linings require additional improvement in mechanical properties by mixing more than one type of additives mentioned in the research. Thus, physical and biological properties can be obtained simultaneously with mechanical properties.The above results qualify the silicone rubber composites for use as a socket liner due to their flexibility and ability to absorb water in addition to their resistance and prevent the growth of fungi and bacteria.The method of preparation and properties of the lining material and additives qualify it for such applications as physical and biological properties.
Impact of vaccine against peste-des-petits ruminants (PPR) in India: An analysis using economic surplus model
Authors: BARDHAN D , SINGH R P , KUMAR SANJAY , ANANDASEKARAN G , MERAJ MOHD
Published: March 2023

Peste-des-Petits Ruminants (PPR) as an acute contagious disease in sheep and goats has proved costly and is considered as one of the most important health constraints in rearing of small ruminants. ICAR-Indian Veterinary Research Institute, Izatnagar had developed a vaccine against the disease through research project during the period 1997-2001. The vaccine has been marketed by various agencies, both public and private since 2007-08 in many states of the country. The economic feasibility of PPR control programme using the above vaccine at the national level was estimated using an economic surplus model. The change in total economic surplus and research and delivery cost were projected from 1997 (year of the start of the research project) to 2030 (by which 100% of small ruminant population is to be vaccinated, as per OIE/FAO specifications) after adjusting for the above adoption pattern. The benefits to society (economic surplus) and costs of control programme were deflated using a suitable consumer price index to 2016 level. Using a long run discount rate of 7.5%, the benefits were compared to researchand delivery cost and the NPV, IRR and BCR were calculated. The change in total surplus as a result of vaccination of sheep and goats against PPR was ₹ 8,253 crore per annum. The study revealed that the vaccination programme resulted into significant economic benefits (NPV= ₹ 489 crore). The IRR and BCR were 119% and 123:1, respectively. Sensitivity analysis revealed that the benefits were most sensitive to higher assumption of discount rate and lower assumption of degree of immunity provided by the vaccine accounting for uncertainties in the efficacy of the vaccine at the field level. In both the case, the net benefits decreased significantly. Net benefits to society also significantly decreased upon the assumption of declining adoption rates and ceiling adoption not reaching 100% level.
Incidence, pathology and diagnosis of fowlpox, pigeonpox and duckpox in Asom
Authors: PATHAK N , BARUAH G K , PATHAK D C , UPADHYAYA T N , BARMAN N N , KALITA N , DEKA P
Published: March 2023

A study was conducted to see the incidence of avian pox in different districts of Asom and one district of Nagaland, where outbreaks, 29 of fowlpox, 13 of pigeonpox and 3 of duckpox were recorded. The age wise morbidity and cause specific mortality in case of fowlpox was recorded at 0–8 weeks (19.63 and 23.60%), at 9–20 weeks (5.57 and 14.43%) and above 20 weeks (1.39 and 11.11%), respectively. Likewise, in pigeonpox, morbidity and cause specific mortality were recorded at 0–8 weeks (11.11, 0%), 9–20 weeks (30.68, 37.03%) and above 20 weeks (35.08, 30%), respectively. Again in case of duckpox, morbidity was recorded at 0–8 weeks (10%), 9–20 weeks (0%) and above 20 weeks (6.66%), while no mortality was recorded among the ducks. External examination revealed erosions, crusts and several small, multifocal to coalescing wart-like nodules on various parts of the affected birds. During post-mortem examination, few birds showed fibronecrotic lesions on mucous membrane of the oral cavity and upper respiratory tract. Histopathological examination of the scab samples revealed intracytoplasmic eosinophilic inclusion bodies. During ultrastructural study, inclusion bodies were seen in the cytoplasm of the skin epithelium,which consist of numerous, dumbbell-shaped bodies typical of pox virions. During molecular diagnosis, out of 29fowlpox, 9 pigeonpox and 3 duckpox suspected samples 86.20, 77.77 and 100% samples, respectively, were foundpositive by polymerase chain reaction.
Comparative analysis of developmental and molecular correlates of developmental competence of buffalo oocytes derived from small and large follicles
Authors: PANDEY SRITI , SOMAL ANJALI , PARMAR M S , GUPTA SWATI , CHANDRA VIKASH , KUMAR G SAI , SHARMA G TARU
Published: March 2023

The present study was conducted to correlate the developmental competence of large follicle (LF, >6 mm) and small follicle (SF, <6 mm) derived buffalo oocytes in terms of morphological assessment and molecular characteristics. A pool of culture grade cumulus oocytes complexes (COCs) from both the groups separately were subjected to brilliant cresyl blue (BCB) staining. LF derived oocytes had significantly higher percentage of BCB+ve oocytes and were larger in size and maturation status was also visibly superior. Cleavage and blastocysts rate was also significantly higher in LF group than SF group. Relative mRNA expression analysis revealed that expression of GDF9 was significantly higher in LF group than SF group while expression of BMP15 increased insignificantly. Expression of GREM1, EGFR and PTGS2 was significantly higher in LF group than SF group while expression of HAS2 was insignificantly higher. Similarly, expression of GLUT1, OCT4 and IFN-ï´ in in vitro produced blastocyts was significantly higher in LF group than SF group. Thus, it can be concluded that LF derived oocytes are larger in size and express higher level of competence markers and resulted in better quality embryos. This information may be further utilized for the enhancement of developmental competence of small follicle derived oocytes.
Boron supplementation provides hepato-protective effect and improves performance in Wistar rats fed calcium deficit diet
Authors: BHASKER T VIJAY , GOWDA N K S , KRISHNAMOORTHY P , PAL D T , SEJIAN V , AWACHAT V B , PATTANAIK A K , VERMA A K
Published: March 2023

This study was conducted to investigate the influence of boron (B) supplementation in rats fed diets with adequate and deficit calcium (Ca). A feeding trial of 90 days duration was conducted in 84 Wistar strain rats divided into 7 groups, viz. Normal-Ca (100%) basal diet (NC) and supplemented with B at 5 (NCB-5), 10 (NCB-10), 20 (NCB-20) and 40 (NCB-40) ppm levels; low-Ca (50%) diet (LC) and supplemented with 40 ppm B (LCB-40). During 80–85 days of feeding, a digestibility trial was conducted to record nutrient digestibility. Rats (8) from each group were sacrificed to collect blood and visceral organs to study biochemical parameters and histopathology. The average daily feed and water intake were similar among the dietary groups. Body weight gain was lower in rats fed LC diet and increased in the LCB-40 group. Nutrient (dry matter, crude protein, crude fat) digestibility was significantly improved with B-supplementation to NC diets. Serum levels of triglycerides, HDL-cholesterol and alanine transaminase were significantly lowered in B-supplemented groups. The levels of glucose, total cholesterol, alkaline phosphatase and aspartate transaminase in serum remained unaltered among the dietary groups. Degenerative changes were observed in the liver of rats fed Ca-deficient diets and were ameliorated with 40 ppm B supplementation. Results indicated that dietary supplementation of B in rats showed improved nutrient digestibility, growth and lowered serum levels of triglycerides, HDL-cholesterol and alanine transaminase. Hepatic tissue alterations due to lower Ca intake were ameliorated with B supplementation.
In-vitro digestibility studies with recombinant Saccharomyces cerevisiae expressing fibre degrading enzyme genes
Authors: VIJAYARANI K , ANUPRIYA R , THULASI A , CHANDRASEKHARAIAH M
Published: March 2023

The present study described the in vitro digestibility of recombinant exo- and endo-glucanase genes of Phanerochaete chrysosporium cloned into pYESDEST-52 vetor and expressed in Saccharomyces cerevisiae. In-vitro RUSITEC trials indicated that recombinant exoglucanase increased the total microbial protein at 24 and 48 h. Overall increase in the in vitro digestibility was observed with both endoglucanase and exoglucanase recombinants. Both the recombinants produced significantly high levels of propionic and acetic acid.
Effect of storage period on special DUS characters in extant varieties of rice (Oryza sativa) for establishing distinctiveness
Authors: SANYAL ARCHANA , JOSHI MONIKA A , BASU SUDIPTA , YADAV SHIV K
Published: March 2023

Under the PPV and FR Act 2001, a number of rice varieties have been registered based on morphological and biochemical DUS descriptors. In the present study, 61 extant varieties of rice (Oryza sativa L.) were characterized based on 55 morphological descriptors at different stages of plant growth. However, for the assessment of biochemical characters, namely; phenol reaction of lemma, amylose content and gelatinization temperature, the assessment is based on ripened seed onwards, and even after the seed is stored. Hence, there is a need to determine optimum period after seed ripening for recording biochemical characters to avoid confusion during grouping of varieties for establishing distinctiveness. For this, all the 61 varieties were examined to see the effect of storage period on biochemical characters. The observations were recorded beginning from freshly harvested seed (0 months) vis-Ã -vis stored seed up to one year (12 months). The data were recorded after every three months up to a period of one year. Results revealed that significant changes begin to occur during six months of storage and continue for remaining period. Phenol reaction of lemma colour in 26 varieties showed significant changes in colour intensity after six months of storage. Gelatinization temperature (GT) and amylose content are important cooking quality traits for rice. Among 61 varieties, 26 showed increase in Gelatinization temperature after six months of storage as ASV decreased from 6.7 to 6.0, while the remaining varieties showed constant ASV. Further, the average percentage of amylose content significantly increased after six months of storage period in all varieties. Hence, storage period significantly influences the character expression of biochemical traits. Therefore, it is recommended that the varieties should be evaluated for the biochemical assessment within six months of harvesting.
Pregnant nursing professionals in the context of the covid-19 pandemic: an experience report
Authors: Albuquerque Nataniele de , Silva Thaísa Mirella da , Meneses Suzana Maria de Oliveira Costa , Silva Sâmela Maria de Oliveira , Diniz Clebiana Alves e silva , Rocha Tainan de Andrade , Magalhães Julia Maria Pacheco Lins , Brito Poliana Silva de , Holanda Manuelle de Araújo , Nunes Eliane dos Santos
Published: March 2023

The emergence of the Covid-19 pandemic has multiplied fears and uncertainties among pregnant women, especially among nurses who experienced pregnancy and the puerperium during the pandemic, due to the greater vulnerability resulting from the specifics of work. Objective: To report the experience of nurses from the Oncology Unit of the HUPAA, pregnant women in the context of the COVID-19 pandemic. Method: This is a descriptive, exploratory, experience report type study. Results: Technological innovation, through remote work, provided a beneficial experience for pregnant nurses, as it allowed them to protect and protect this group, ensuring greater safety for the mother-child binomial.
Burnout syndrome in medicine students: an integrative literature review
Authors: Ruy Bruna Tainah , Barbosa Ana Cláudia Mendes , Ferreira Neto Pedro Paulo Martins , Teixeira Vanessa da Silva Moreira , Santos Millena Cardoso Sales , Zuim Nicoli Lindissey , Brito Isadora pereira , Abreu Jordana Vaz de
Published: March 2023

Burnout Syndrome (BS) is a set of signs and symptoms of psychological origin, in which the individual presents, mainly, physical/emotional exhaustion, psychological exhaustion, depersonalization and low personal fulfillment. Professionals who maintain an intense work routine are more predictable to contract Burnout, including medical students among these individuals. The present article aims to evaluate the prevalence of risk factors as well as the consequences of Burnout Syndrome in medical students. The present study is an integrative literature review of a quantitative nature. PubMed and Medline were used as a database. The descriptors in Health Sciences (DeCS) were used: "medical students", "burnout syndrome" and "public health". Among the analyzed literature, it was noted that the prevalence of Burnout is approximately 50% among the academic environment. Of this total, 25 to 75% refer to intentions of dropping out of the course, suicidal ideation, caused by overload and emotional exhaustion. Among the analyzed sexes, the female is the one that suffers the most from this disease, women over 21 years old are targets of mental exhaustion, depersonalization and worsening of health. Regarding the period of college, even if their academic performance is satisfactory, there is a prevalence of SB among students from the 1st to the 10th period. A high relationship between the Syndrome and lack of sleep has been demonstrated, which causes damage to physical and psychological well-being. To make the situation even worse, many use unhealthy habits, such as the use of sedative and psychoactive drugs, as well as energy drinks to feel capable of performing their academic tasks. In this sense, it is noted that medical students have a high probability of developing BS, due to high study hours, exhausting routine and feeling of helplessness, among other factors. Many of these academics have suicidal thoughts and emotional problems. In view of this, it is necessary to further study this theme in order to reduce or even end these sufferings.
Characterization of chitosana films produced with incorporation of anacardium microcarpum ducke extract
Authors: Pereira Ronaldo Coelho , Sousa Maura Vieira dos Santos , Macêdo Marina de Oliveira Cardoso , Viana Vicente Galber Freitas , Macêdo Haroldo Reis Alves de
Published: March 2023

Chitosan is a polysaccharide derived from the chitin deacetylation process with wide versatility of applications in different areas such as agriculture, tissue engineering, pharmaceutical, food industry, dentistry, among others. Tissue engineering is one of the prominent areas in research involving chitosan, due to its properties such as low toxicity, bioactivity and biocompatibility. Several studies have associated chitosan with other biomaterials that have favorable biological effects to the healing process seeking the production of films with potential for biomedical application., from this perspective, this work aimed at the production and physicochemical characterization of chitosan films with the incorporation of Anacardium microcarpum Ducke extract, (“cajuí”), aiming at the production of a biomaterial for biomedical applications. Analysis of films by the techniques of: optical microscopy; contact angle; superficial tension; thermogravimetric analysis (TGA) and water absorption showed changes in the surface properties of the films that received extract, respectively, these showed higher heterogeneity, increased hydrophilic character, and greater degradation in aqueous medium than pure films.
Contribuição da responsabilidade social universitária para o desenvolvimento sustentável latino-americano
Authors: Borelli Elizabeth , Cruz Myrt Thânia de Sousa , Mattozo Kátia de Goes , Cardoso Luiz Henrique Santos
Published: March 2023

A temática da Responsabilidade Social Universitária se apresenta como um conceito amplo e dinâmico, atrelado ao processo de formação da sociedade latino-americana e às práticas de gestão da universidade. Nessa perspectiva de análise, tem-se como problema formulado por esta pesquisa: “a implementação da Política de Responsabilidade Social Universitária, utilizando o Modelo URSULA, reúne condições para alcançar os objetivos do desenvolvimento sustentável da Agenda 2030?” A partir de uma metodologia centrada na abordagem qualitativa, utilizando a análise documental, de natureza descritiva-analítica, concluiu-se que suas práticas de atuação configuram um cenário favorável ao tema da sustentabilidade e da relação universidade-sociedade.
Diagnóstico e plano de implementação da ferramenta 5S em uma empresa de radiologia no município de Campos dos Goytacazes
Authors: Andrade Juan Victor Viana de , Bastos Luiz Augusto Gonçalves da Silva Dutra
Published: March 2023

A prestação de serviço de saúde no Brasil está comprometida, com raras exceções. Principalmente nos setores públicos. O cliente, por sua vez, está cada vez mais exigente, quanto à qualidade dos serviços prestados. Esta pesquisa teve como objetivo geral fazer um estudo de caso sobre a ferramenta 5S e seus benefícios, se aplicada em uma clínica de radiologia, do município de Campos dos Goytacazes, norte do estado do Rio de Janeiro. São objetivos específicos do trabalho: a) Fazer um levantamento detalhado de todos os serviços prestados pela empresa de radiologia e descrever os processos de cada um deles. b) Diagnosticar a atual situação da empresa, através da avaliação da percepção dos funcionários, em relação à metodologia 5S; c) Analisar a viabilidade de implementação da metodologia na organização. d) Propor a aplicação do método a partir dos resultados obtidos. A proposta foi analisar os benefícios de sua aplicação, e salientar possíveis intervenções, sinalizando pontos que mereciam atenção. A metodologia enquadra-se nos moldes de um estudo de caso de caráter descritivo, com dados obtidos in loco. Para tanto, foi elaborado um roteiro preliminar, para coleta de dados, através de um questionário aplicado aos colaboradores, e posterior análise do mesmo. Por fim, a implementação da ferramenta 5S foi recomendada a clínica, com intuito de evidenciar sua preocupação quanto à gestão de qualidade. Seu custo de aplicação e manutenção é relativamente baixo, perto dos objetivos com ela alcançados. Além de tornar os processos mais claros, ágeis, eficientes e produtivos na clínica radiológica.
Inovação de métodos e processos educacionais no período pandêmico: caso do município de Iporá, Goiás
Authors: Lima Ana Paula Ferreira de , Saraiva Flaviany Marques Ferraz , Souza Pedro Vinícius Barreto , Pires Roseli Vieira
Published: March 2023

O presente artigo tem como objeto de estudo a inovação de métodos e processos educacionais no período pandêmico: caso do município de Iporá. É intuito do trabalho descrever o modelo conceitual de métodos e processos da gestão educacional aplicado a rede municipal de educação de Iporá no período pandêmico. No que refere-se à construção do referencial teórico, os autores que, por hora, puderam compor o referencial teórico-metodológico deste trabalho são: Bisol (2018), Camargo (2018), Oliveira (2018), Portela (2021), Caldwell (2013), Camargo (2018), Garofalo (2020). Para o desenvolvimento deste artigo, os métodos e as técnicas empregadas foram baseados na pesquisa documental de fonte primária, através dos documentos oficiais da SME – Secretaria Municipal de Educação (Iporá-GO), e de fonte secundária por meio da pesquisa bibliográfica para abordagem e discussão dos dados coletados. Como técnicas de coleta de dados, utilizou-se a investigação direta intensiva. Portanto, ao final deste artigo podemos entender a importância da inovação educacional como aporte sobre conceitos, processos e métodos para o ensino, que proporcionem equidades sociais, desenvolvendo o educando em sua integralidade, primando pela qualidade educacional, possibilitando identificar os limites e o papel do grupo gestor na implementação de um processo educativo que envolva práticas inovadoras, independentemente das suas especificidades, driblando assim, as conjecturas contraproducentes.
La importancia de utilizar metodologías activas en las clases de ciencias de la educación fundamental
Authors: Santos João Soares , Anjos Érika Cristina Teixeira Dos , Avendaño Fernando Carlos
Published: March 2023

¿Por qué es importante que los niños desarrollen el pensamiento científico desde muy temprano? ¿Cómo enseñar a los estudiantes a pensar científicamente? ¿Qué tipo de enseñanza refleja el espíritu de la investigación científ ica? ¿Cómo desenvolver esa práctica en el trabajo cotidiano de las escuelas? De acuerdo con la autora Melina Furman, 2009, esas preguntas son pertinentes en lo referente a la Enseñanza de Ciencias, dirigida a la enseñanza fundamental. Pero, a final, ¿qué es enseñar Ciencias y cuáles son sus enfoques para la Enseñanza Fundamental? (FURMAN, 2009).
WQI of the source of the Sussuapara stream in the dry and rainy months in the city of Palmas - TO
Authors: Pereira Jucilene da Costa , Naoe Alessandra Maria de Lima , Silva Roberta Araújo e , Ries Eduardo Silva
Published: March 2023

Springs are important environmental systems for the maintenance of hydrological, geomorphological and biological balance. However, in urban areas, these springs have been intensely modified by human action. One of the main consequences of urban interventions on the dynamics of springs is changes in water quality. One of the main consequences of urban interventions on the dynamics of springs is changes in water quality. In addition, periods of greater precipitation can interfere with this dynamic. Therefore, the present study aimed to evaluate the water quality index - WQI at the source of the Sussuapara stream in the municipality of Palmas-TO in the year 2021. Nine parameters were studied to assess water quality; four samples were collected in the dry months and four in the rainy months. The results obtained were compared with Conama Resolution no. 357 and showed that the WQI of the headwaters of the Sussuapara stream in the dry months was higher than in the rainy months, being classified as "Good" and "Regular", respectively. The results showed that the impacts caused by surface runoff and location of the spring are significant in the water quality index.
Hypertensive crisis in hospital emergency and urgent care: how to care?
Authors: Diniz Clebiana Alves e Silva , Rocha Tainan de Andrade , Magalhães Julia Maria Pacheco Lins , Albuquerque Nataniele de , Silva Sâmela Maria de Oliveira , Brito Poliana Silva de , Meneses Suzana Maria de Oliveira Costa , Silva Thaísa Mirella da , Nunes Eliane dos Santos , Holanda Manuelle de Araújo
Published: March 2023

The hypertensive crisis is one of the complications of arterial hypertension, characterized by a sudden increase in blood pressure, with the possibility of damage to target organs, which increases the risk of death. This article aimed to analyze the care provided to hypertensive crisis in urgent and emergency care through scientific production. This is a bibliographic review. The selection of works for this review was based on bibliographical research carried out in scientific production indexes (BIREME, LILACS, SCIELLO) with the descriptors hypertensive crisis, urgent and emergency care in hypertensive crisis, full scientific articles and published abstracts were chosen. This study focused on the hypertensive crisis, showing the importance of emergency care, the risk factors associated with the crisis, the common characteristics and the clinical conditions presented. It then becomes necessary to disseminate guidelines for the care of hypertensive crises, thus providing better quality care, without complications and unnecessary expenses.
Use of canabidiol as a treatment alternative for alzheimer's: a literature review
Authors: Silva João Vitor Martins da , Reis Romana Rodrigues Andrade , Silva Luíza Madureira , Mesquita Dara da Silva , Honório Júnior José Eduardo Ribeiro
Published: March 2023

Alzheimer's disease is a neurodegenerative disease in which progressive memory loss occurs and presents cognitive symptoms. Currently, the number of studies with Cannabidiol as a treatment alternative for Alzheimer's disease is growing due to its neuroprotective factor. Research indicates that cannabidiol has the ability to control microglial and neuroinflammation function, favoring the survival rate of cells by combining its anti-inflammatory, antioxidant and neuroprotective effects, which act against toxicity caused by the accumulation of beta-amyloid peptides.