bluuebunny/crossref_metadata_2025 huggingface dataset:
Elaboration of High Permeable Macrovoid Free Polysulfone Hollow Fiber Membranes for Air Separation
Authors: Dibrov George , Ivanov Mikhail , Semyashkin Mikhail , Sudin Vladislav , Fateev Nikita , Kagramanov George
Published: May 2019

In this work, polysulfone hollow fibers with oxygen permeance 70 L (STP)/(m2·h·bar) and selectivity α(O2/N2) = 6 were obtained. A decrease in the dope solution temperature allowed to diminish macrovoids due to the increase of the dope viscosity from 15.5 Pa·s at 62 °C to 35 Pa·s at 25 °C. To reduce the fiber diameter, thereby increasing the packing density, they were spun at high linear velocities. A hollow fiber membrane element was produced with effective membrane area 2.75 m2 and packing density 53%. Its air separation performance was evaluated to bridge laboratory studies and practical application.
Genome-Wide Association Studies Based on Equine Joint Angle Measurements Reveal New QTL Affecting the Conformation of Horses
Authors: Gmel Annik Imogen , Druml Thomas , von Niederhäusern Rudolf , Leeb Tosso , Neuditschko Markus
Published: May 2019

The evaluation of conformation traits is an important part of selection for breeding stallions and mares. Some of these judged conformation traits involve joint angles that are associated with performance, health, and longevity. To improve our understanding of the genetic background of joint angles in horses, we have objectively measured the angles of the poll, elbow, carpal, fetlock (front and hind), hip, stifle, and hock joints based on one photograph of each of the 300 Franches-Montagnes (FM) and 224 Lipizzan (LIP) horses. After quality control, genome-wide association studies (GWASs) for these traits were performed on 495 horses, using 374,070 genome-wide single nucleotide polymorphisms (SNPs) in a mixed-effect model. We identified two significant quantitative trait loci (QTL) for the poll angle on ECA28 (p = 1.36 × 10−7), 50 kb downstream of the ALX1 gene, involved in cranial morphology, and for the elbow joint on ECA29 (p = 1.69 × 10−7), 49 kb downstream of the RSU1 gene, and 75 kb upstream of the PTER gene. Both genes are associated with bone mineral density in humans. Furthermore, we identified other suggestive QTL associated with the stifle joint on ECA8 (p = 3.10 × 10−7); the poll on ECA1 (p = 6.83 × 10−7); the fetlock joint of the hind limb on ECA27 (p = 5.42 × 10−7); and the carpal joint angle on ECA3 (p = 6.24 × 10−7), ECA4 (p = 6.07 × 10−7), and ECA7 (p = 8.83 × 10−7). The application of angular measurements in genetic studies may increase our understanding of the underlying genetic effects of important traits in equine breeding.
Molecular Data Reveal Multiple Lineages in Piranhas of the Genus Pygocentrus (Teleostei, Characiformes)
Authors: Mateussi Nadayca T.B. , Melo Bruno F. , Foresti Fausto , Oliveira Claudio
Published: May 2019

Carnivorous piranhas are distributed in four serrasalmid genera including Pygocentrus, which inhabit major river basins of South America. While P. cariba and P. piraya are endemics of the Orinoco and São Francisco basins, respectively, P. nattereri is widely distributed across the Amazonas, Essequibo, lower Paraná, Paraguay, and coastal rivers of northeastern Brazil, with recent records of introductions in Asia. Few studies have focused on the genetic diversity and systematics of Pygocentrus and the putative presence of additional species within P. nattereri has never been the subject of a detailed molecular study. Here we aimed to delimit species of Pygocentrus, test the phylogeographic structure of P. nattereri, and access the origin of introduced specimens of P. nattereri in Asia. Phylogenetic analyses based on a mitochondrial dataset involving maximum-likelihood tree reconstruction, genetic distances, Bayesian analysis, three delimitation approaches, and haplotype analysis corroborate the morphological hypothesis of the occurrence of three species of Pygocentrus. However, we provide here strong evidence that P. nattereri contains at least five phylogeographically-structured lineages in the Amazonas, Guaporé (type locality), Itapecuru, Paraná/Paraguay, and Tocantins/Araguaia river basins. We finally found that the introduced specimens in Asia consistently descend from the lineage of P. nattereri from the main Rio Amazonas. These results contribute to future research aimed to detect morphological variation that may occur in those genetic lineages of Pygocentrus.
Evaluation of Compatibility, Growth Characteristics, and Yield of Tomato Grafted on Potato (‘Pomato’)
Authors: Arefin S. M. Anamul , Zeba Naheed , Solaiman Abul Hasnat , Naznin Most Tahera , Azad Md Obyedul Kalam , Tabassum Mourita , Park Cheol Ho
Published: May 2019

The aim of this study was to evaluate the grafting compatibility of different varieties of tomato (Solanum lycopersicum L.) scions on potato (Solanum tuberosum L.) rootstocks to develop a ‘pomato’ plant. In this study three potato varieties; Diamant (P1), Cardinal (P2) and Asterix (P3), and two tomato varieties; Bangladesh Agricultural Research Institute (BARI) tomato-2 (T1) and BARI tomato-11 (T2) were used to make the grafted combinations T1P1, T1P2, T1P3, T2P1, T2P2 and T2P3, designated G1, G2, G3, G4, G5, and G6, respectively. Tomato seedlings aged 25 (S1) and 35 days (S2) were selected as scions. Graft compatibility was analyzed based on the growth and yield of the pomato plants. The results revealed that varieties and scion age had a significant effect on the pomato fruit and tuber yield. The initiation of flowering was not affected by the various graft combinations; however, plant height, leaf number, branch number, number of clusters per plant, number of fruit per cluster, number of fruit per plant, fruit length, fruit diameter, single fruit weight and total fruit yield per plant were higher in G5S1 among the combinations. On the other hand, the number of tubers per plant, single tuber weight, and tuber yield per plant were highest for a few combinations. Overall, it was concluded that Cardinal (P2) and Asterix (P3) potato were the most compatible for grafting with BARI tomato-11 (T2) at the scion age of 25 days (S1), based on vegetative growth and fruit and tuber yield of pomato plants.
Approach to Yield Response of Young Almond Trees to Deficit Irrigation and Biostimulant Applications
Authors: Gutiérrez-Gordillo Saray , García-Tejero Iván Francisco , García-Escalera Amelia , Galindo Pedro , Arco María del Carmen , Durán Zuazo Víctor Hugo
Published: May 2019

Water is the most limiting resource in many semi-arid areas of Mediterranean countries. Among the strategies to improve water productivity, the implementation of deficit irrigation (DI) strategies and the introduction of drought-tolerant crops in irrigated areas (such as almond) are being widely studied. Recently, the use of biostimulants to enhance crop tolerance to drought under water-scarcity scenarios is increasing. This work examines the response of three almond cultivars (‘Guara’, ‘Marta’, and ‘Lauranne’) in terms of yield and associated physiological responses in the main phenological stages to biostimulants (HYT® A and HYT® B plus) applied to young trees subjected to different irrigation levels: (i) a full irrigation treatment (FI), irrigated at 100% of crop evapotranspiration (ETC); and (ii) sustained-deficit irrigation (SDI75), irrigated at 75% of ETC. Significantly higher yields were obtained with HYT applications in 2 of 3 cultivars; these differences were most evident in the SDI75 treatment. In particular, ‘Guara’ registered the most significant improvements in nut yield when the HYT product was applied (15–20% higher). With regard to crop physiological responses, higher values of leaf water potential and stomatal conductance were noted with the HYT application in some cultivars and phenological stages. These results indicated that the use of biostimulants can be a feasible strategy for almond cultivation, especially when SDI is used.
Mathematical Modeling Framework of Physical Effects Induced by Sediments Handling Operations in Marine and Coastal Areas
Authors: Lisi Iolanda , Feola Alessandra , Bruschi Antonello , Pedroncini Andrea , Pasquali Davide , Di Risio Marcello
Published: May 2019

In recent years increasing attention has been paid to environmental effects that may result from marine dredging and disposal operations. In general, the fine-grained fraction of handled sediments can be dispersed far from the intervention site as a turbidity plume, depending on the specific site and operational parameters. Starting from a literature review, this paper suggests standards for estimating and characterizing the sediment source term, for setting up far-field modeling studies and analyzing numerical results, with the aim of optimizing, also from an economic point of view, the different project, execution and monitoring phases. The paper proposes an integrated modeling approach for simulating sediment dispersion due to sediment handling operations in different marine-coastal areas (off-shore, near-shore and semi-enclosed basins). Attention is paid to the characterization of sediment source terms due to different operational phases (removal, transport and disposal). The paper also deals with the definition of accuracy level of modeling activities, with regard to the main physical processes characterizing the different marine–coastal areas and to the type of environmental critical issues near the intervention site (if any). The main relationships between modeling and monitoring are given for the different design and management phases to support the selection of appropriate technical alternatives and monitoring actions and to ensure the environmental compliance of the proposed interventions.
Numerical Modeling and Experimental Behavior of Closed-Cell Aluminum Foam Fabricated by the Gas Blowing Method under Compressive Loading
Authors: Sharma Varun , Zivic Fatima , Grujovic Nenad , Babcsan Norbert , Babcsan Judith
Published: May 2019

This paper deals with the experimental and numerical study of closed-cell aluminum-based foam under compressive loading. Experimental samples were produced by the gas blowing method. Foam samples had an average cell size of around 1 mm, with sizes in the range 0.5–5 mm, and foam density of 0.6 g/cm3. Foam samples were subjected to a uniaxial compression test, at a displacement rate of 0.001 mm/s. Load and stress were monitored as the functions of extension and strain, respectively. For numerical modeling, CT scan images of experimental samples were used to create a volume model. Solid 3D quadratic tetrahedron mesh with TETRA 10-node elements was applied, with isotropic material behavior. A nonlinear static test with an elasto-plastic model was used in the numerical simulation, with von Mises criteria, and strain was kept below 10% by the software. Uniform compressive loading was set up over the top sample surface, in the y-axis direction only. Experimental tests showed that a 90 kN load produced complete failure of the sample, and three zones were exhibited: an elastic region, a rather uniform plateau region (around 23 MPa) and a densification region that started around 35 MPa. Yielding, or collapse stress, was achieved around 20 MPa. The densification region and a rapid rise in stress began at around 52% of sample deformation. The numerical model showed both compressive and tensile stresses within the complex stress field, indicating that shear also had a prominent role. Mainly compressive stresses were exhibited in the zones of the larger cells, whereas tensile stresses occurred in zones with an increased number of small cells and thin cell walls.
The Size Effect of TiO2 Hollow Microspheres on Photovoltaic Performance of ZnS/CdS Quantum Dots Sensitized Solar Cell
Authors: Li Zhen , Yu Libo
Published: May 2019

Size controllable TiO2 hollow microspheres (HMS) were synthesized by a carbonaceous spheres (CS) template method. Based on TiO2 HMS, the ZnS/CdS quantum dots (QDs) were loaded to form a ZnS/CdS@TiO2 HMS photoanode for quantum dots sensitized solar cell (QDSSC). The size effects of TiO2 HMS on photovoltaic performance were investigated, and showed that TiO2 HMS with sizes ~560 nm produced the best short-circuit current density (Jsc) of 8.02 mA cm−2 and highest power conversion efficiency (PCE) of 1.83%, showing a better photovoltaic performance than any other QDSSCs based on TiO2 HMS with size ~330 nm, ~400 nm, and ~700 nm. The improvement of photovoltaic performance based on ~560 nm TiO2 HMS which can be ascribed to the enhanced light harvesting efficiency caused by multiple light reflection and strong light scattering of TiO2 HMS. The ultraviolet-visible (UV-vis) spectra and incident photo to the current conversion efficiency (IPCE) test results confirmed that the size of TiO2 HMS has an obvious effect on light harvesting efficiency. A further application of ~560 nm TiO2 HMS in ZnS/PbS/CdS QDSSC can improve the PCE to 2.73%, showing that TiO2 HMS has wide applicability in the design of QDSSCs.
Investigation of the In-Plane Mechanical Anisotropy of Magnesium Alloy AZ31B-O by VPSC–TDT Crystal Plasticity Model
Authors: Zhang Bo , Li Shuangming , Wang Huamiao , Tang Weiqin , Jiang Yaodong , Wu Peidong
Published: May 2019

The in-plane mechanical anisotropy of magnesium alloy sheet, which significantly influences the design of the parts produced by Mg alloy sheets, is of great importance regarding its wide application. Though the stress–strain response and texture evolution have been intensively investigated, and the anisotropy of Mg alloy can be significantly substantiated by its R-value, which reveals the lateral response of a material other than the primary response. As a consequence, the conjunction of viscoplastic self-consistent model and twinning and detwinning scheme (VPSC–TDT) is employed to investigate the in-plane anisotropy of magnesium alloy AZ31B-O sheet. The loading cases include both tension and compression along different paths with respect to the processing direction of the sheet. It is revealed that the stress–strain relation, texture evolution, R-value, and involved deformation mechanisms are all loading path-dependent. The unique R-values of Mg alloys are interpreted with the aid of modeling behaviors of Mg single crystals. The results agree well with the corresponding experiments. It is found that the hexagonal close-packed (HCP) crystallographic structure, deformation twinning, and initial basal texture are responsible for the characteristic behavior of Mg alloys.
Thermal Decomposition and Ceramifying Process of Ceramifiable Silicone Rubber Composite with Hydrated Zinc Borate
Authors: Song Jiuqiang , Huang Zhixiong , Qin Yan , Li Xinyi
Published: May 2019

The ceramifiable silicone rubber composite was prepared using hydrated zinc borate and kaolin as ceramifiable fillers. Effects of the hydrated zinc borate content and the combustion temperature on the properties of the ceramifiable silicone rubber composite were investigated. Thermal decomposition and ceramifying processes of the composite in a muffle furnace under air were also studied. The results showed that the density and the hardness of the composites increased as the content of the hydrated zinc borate increased from 0 to 30 phr. The tensile strength and elongation at break decreased. In addition, hydrated zinc borate decreased the decomposition temperature of the composite, whereas the residue weight under air atmosphere was increased. In the process of decomposition and oxidation of the ceramifiable silicone rubber composite in air, B2O3 was generated by the decomposition of zinc borate and participated in the formation of the residue network structure, which decreased the temperature of the ceramifying transition. The new phases, zinc aluminate (ZnO·Al2O3) and aluminum-rich mullite (9Al2O3·2SiO2), appeared after high-temperature thermochemical reactions. Microscopy images revealed that different structures were formed at different temperatures. The network structure of the ceramic residue became increasingly compact, and the compressive strength increased from 0.31 to 1.82 MPa with the increase of temperature from 800 to 1400 °C, which had a better protective effect on heat transfer and mass loss. The weight loss and the linear shrinkage of the ceramic residue was 37.6% and 21.9%, respectively, with the 30 phr content of hydrated zinc borate. The bending strength was improved from 0.11 to 11.58 MPa, and the compressive strength also increased from 0.03 to 1.14 MPa.
Microstructure and Grain Orientation Evolution in SnPb/SnAgCu Interconnects Under Electrical Current Stressing at Cryogenic Temperature
Authors: Fu Xing , En Yunfei , Zhou Bin , Chen Si , Huang Yun , He Xiaoqi , Chen Hongtao , Yao Ruohe
Published: May 2019

Electromigration was characterized at the cathode Cu/solder interface—without the effect of Joule heating—by employing scanning electron microscopy (SEM) and electron backscatter diffraction (EBSD) analyses. Rapid (Cux,Ni1−x)6Sn5 intermetallic compound (IMC) growth was observed at the anomalous region at the cathode end due to the effect of current crowding. The abnormal isotropic diffusion and parallel distribution of Pb were characterized in an ultra-low temperature environment in a monocrystalline structure stressed at −196 °C. The interesting results were attributed to crystallographic transformation due to the simultaneous effect of cryogenic and electrical stressing. The diffusion behavior of Pb atoms in face-centered cubic lattices performed isomorphism. As a result, Pb atoms of the bump gathered at the high-energy grain boundaries by diffusing through the face-centered cubic lattices around the long grain boundary, eventually forming a long-range distribution and accumulation of Pb elements. Our study may provide understanding of cryogenic electromigration evolution of the Cu/solder interface and provide visual data for abnormal lattice transformation at the current stressing.
Quenching Sensitivity of Al-Zn-Mg Alloy after Non-Isothermal Heat Treatment
Authors: Li Shuai , Dong Honggang , Wang Xingxing , Liu Zhongying
Published: May 2019

Type Al-Zn-Mg alloy has a wide ranges of application in vehicles, but corrosion resistance and mechanical properties of this alloy after heat treatment or heat straightening limits its utilization. This paper investigates the effect of quenching condition during non-isothermal heat treatment on corrosion behavior and mechanical properties of Al-Zn-Mg alloy. The corrosion resistance of Al-Zn-Mg alloy decreases after non-isothermal heat treatment and the sample after air quenching has the lowest corrosion resistance, the specimens can get better corrosion resistance when suffered 5 min air cooling followed by water quenching process. The evolution of mechanical properties and corrosion resistance of heat-treated specimens is caused by the modification of distribution of precipitates at grain boundary and the microchemistry of precipitates at grain boundary, precipitate-free zones and the matrix.
Powder Metallurgy Synthesis of Heusler Alloys: Effects of Process Parameters
Authors: Ahamed Riaz , Ghomashchi Reza , Xie Zonghan , Chen Lei
Published: May 2019

Ni45Co5Mn40Sn10 Heusler alloy was fabricated with elemental powders, using a powder processing route of press and sinter, in place of vacuum induction melting or arc melting route. The effects of process parameters, such as compaction load, sintering time, and temperature, on the transformation characteristics and microstructures of the alloy were investigated. While the effect of compaction pressure was not significant, those of sintering time and temperature are important in causing or annulling martensitic transformation, which is characteristic of Heusler alloys. The processing condition of 1050 °C/24 h was identified to be favorable in producing ferromagnetic Heusler alloy. Longer durations of sintering resulted in an increased γ-phase fraction, which acts as an impediment to the structural transformation.
An Overview of Normally-Off GaN-Based High Electron Mobility Transistors
Authors: Roccaforte Fabrizio , Greco Giuseppe , Fiorenza Patrick , Iucolano Ferdinando
Published: May 2019

Today, the introduction of wide band gap (WBG) semiconductors in power electronics has become mandatory to improve the energy efficiency of devices and modules and to reduce the overall electric power consumption in the world. Due to its excellent properties, gallium nitride (GaN) and related alloys (e.g., AlxGa1−xN) are promising semiconductors for the next generation of high-power and high-frequency devices. However, there are still several technological concerns hindering the complete exploitation of these materials. As an example, high electron mobility transistors (HEMTs) based on AlGaN/GaN heterostructures are inherently normally-on devices. However, normally-off operation is often desired in many power electronics applications. This review paper will give a brief overview on some scientific and technological aspects related to the current normally-off GaN HEMTs technology. A special focus will be put on the p-GaN gate and on the recessed gate hybrid metal insulator semiconductor high electron mobility transistor (MISHEMT), discussing the role of the metal on the p-GaN gate and of the insulator in the recessed MISHEMT region. Finally, the advantages and disadvantages in the processing and performances of the most common technological solutions for normally-off GaN transistors will be summarized.
Effects of the Consumption of Prickly Pear Cacti (Opuntia spp.) and its Products on Blood Glucose Levels and Insulin: A Systematic Review
Authors: Gouws Caroline A. , Georgousopoulou Ekavi N. , Mellor Duane D. , McKune Andrew , Naumovski Nenad
Published: May 2019

Background and Objectives: There is confusion as to which component of the Opuntia spp. cacti has demonstrated anti-hyperglycemic effects or anti-diabetic properties. It is important to clarify these health benefits due to the increasing need for prevention and treatment of chronic diseases. The aim of this review is to identify the effects of Opuntia spp. cacti consumption on biomedical measures; glucose and insulin with consideration of its’ components; fruit, leaf and combined or unidentified Opuntia spp. products. Materials and Methods: Prior to commencing the searches, this systematic review was registered with PROSPERO (CRD42018108765). Following the PRISMA 2009 guidelines, six electronic databases (Food Science and Technology Abstracts (EBSCO), Medline, Scopus, CINAHL, Web of Science and Cochrane) were searched for articles investigating the effect of Opuntia spp. consumption on glucose and insulin in humans. Results: Initially, 335 articles were sourced and filtered by exclusion criteria (human interventions, control trials and articles published in English) resulting in 20 relevant articles. The included studies were characterized by such plant components as fruit (n = 4), cladode (n = 12), and other Opuntia spp. products (n = 4), further separated by clinical populations (‘healthy’, hyperlipidemic, hypercholesterolemic, Type 2 Diabetes Mellitus). The findings of this review indicate variations in effects between cacti components and products. Cladode and select Opuntia spp. products predominately demonstrated significant reductions in serum glucose and insulin, indicating potential as a functional food candidate. Prickly Pear fruit was predominately reported to have no significant effects on glucose or insulin. The quality of evidence appeared to vary based on the type of Opuntia spp. product used. Studies that used specifically the fruit or cladode had high risk of bias, whereas studies which used combined Opuntia spp. products had a lower risk of bias. Numerous mechanisms of action were proposed where positive findings were reported, with emphasis on dualistic glucose-dependent and independent actions, however, mechanisms require further elucidation. Conclusion: Currently, there is a lack of evidence to support the recommendation of using Opuntia spp. fruit products as an alternative or complementary therapy in the reduction of risk or management of Type 2 Diabetes Mellitus. The Cladode does however show promise in potential glucose-lowering effects which warrant further investigation.
Five-Year Data on Pollen Monitoring, Distribution and Health Impact of Allergenic Plants in Bucharest and the Southeastern Region of Romania
Authors: Leru Polliana Mihaela , Eftimie Ana-Maria , Anton Vlad Florin , Thibaudon Michel
Published: May 2019

Background and objectives: Respiratory allergies induced by allergenic pollen represent an important public health problem with increasing prevalence and severity in Europe. Romania has no aerobiology network and pollen measurements have been done for about ten years in the west region only. Materials and Methods: We established the first pollen monitoring center in the capital of Bucharest in 2013, based on collaboration with the Réseau National de Surveillance Aérobiologique (RNSA) from France. The aim of our paper is to present results from five years of pollen monitoring in the city center of Bucharest and preliminary data on distribution and health impact of some allergenic plants, mainly Ambrosia artemisiifolia, which is considered a real danger for the public health. Results: Our data show a significant atmospheric amount and a longer season than previously considered of grass (Gramineae) pollen and short period with a high level of Ambrosia pollen, while tree pollen looks less important in this area. The plant distribution data provided by specialists and information from affected persons showed the wide and increasing spread of Ambrosia in Bucharest and other cities from the south region. Preliminary health data from allergists confirmed that the number of patients with allergies to Ambrosia pollen is increasing from one year to another and almost all patients describe a high urban exposure from their living or working place. Conclusions: We consider that the recently implemented Law 62/2018 against Ambrosia may help reduce weed distribution and the atmospheric pollen load, but a more complex and coordinated strategy for controlling urban vegetation and reducing biologic pollution is needed.
Modeling and Analysis of the Noise Performance of the Capacitive Sensing Circuit with a Differential Transformer
Authors: Xie Yafei , Fan Ji , Zhao Chun , Yan Shitao , Hu Chenyuan , Tu Liangcheng
Published: May 2019

Capacitive sensing is a key technique to measure the test mass movement with a high resolution for space-borne gravitational wave detectors, such as Laser Interferometer Space Antenna (LISA) and TianQin. The capacitance resolution requirement of TianQin is higher than that of LISA, as the arm length of TianQin is about 15 times shorter. In this paper, the transfer function and capacitance measurement noise of the circuit are modeled and analyzed. Figure-of-merits, including the product of the inductance L and the quality factor Q of the transformer, are proposed to optimize the transformer and the capacitance measurement resolution of the circuit. The LQ product improvement and the resonant frequency augmentation are the key factors to enhance the capacitance measurement resolution. We fabricated a transformer with a high LQ product over a wide frequency band. The evaluation showed that the transformer can generate a capacitance resolution of 0.11 aF/Hz1/2 at a resonant frequency of 200 kHz, and the amplitude of the injection wave would be 0.6 V. This result supports the potential application of the proposed transformer in space-borne gravitational wave detection and demonstrates that it could relieve the stringent requirements for other parameters in the TianQin mission.
TiO2 Based Nanostructures for Photocatalytic CO2 Conversion to Valuable Chemicals
Authors: Razzaq Abdul , In Su-Il
Published: May 2019

Photocatalytic conversion of CO2 to useful products is an alluring approach for acquiring the two-fold benefits of normalizing excess atmospheric CO2 levels and the production of solar chemicals/fuels. Therefore, photocatalytic materials are continuously being developed with enhanced performance in accordance with their respective domains. In recent years, nanostructured photocatalysts such as one dimensional (1-D), two dimensional (2-D) and three dimensional (3-D)/hierarchical have been a subject of great importance because of their explicit advantages over 0-D photocatalysts, including high surface areas, effective charge separation, directional charge transport, and light trapping/scattering effects. Furthermore, the strategy of doping (metals and non-metals), as well as coupling with a secondary material (noble metals, another semiconductor material, graphene, etc.), of nanostructured photocatalysts has resulted in an amplified photocatalytic performance. In the present review article, various titanium dioxide (TiO2)-based nanostructured photocatalysts are briefly overviewed with respect to their application in photocatalytic CO2 conversion to value-added chemicals. This review primarily focuses on the latest developments in TiO2-based nanostructures, specifically 1-D (TiO2 nanotubes, nanorods, nanowires, nanobelts etc.) and 2-D (TiO2 nanosheets, nanolayers), and the reaction conditions and analysis of key parameters and their role in the up-grading and augmentation of photocatalytic performance. Moreover, TiO2-based 3-D and/or hierarchical nanostructures for CO2 conversions are also briefly scrutinized, as they exhibit excellent performance based on the special nanostructure framework, and can be an exemplary photocatalyst architecture demonstrating an admirable performance in the near future.
Oral Administration of a Select Mixture of Lactobacillus and Bacillus Alleviates Inflammation and Maintains Mucosal Barrier Integrity in the Ileum of Pigs Challenged with Salmonella Infantis
Authors: Liu Xiao , Xia Bing , He Ting , Li Dan , Su Jin-Hui , Guo Liang , Wang Jiu-feng , Zhu Yao-Hong
Published: May 2019

Salmonella is important as both a cause of clinical disease in swine and as a source of food-borne transmission of disease to humans. Lactobacillus and Bacillus are often used as antibiotic substitutes to prevent Salmonella infection. In this study, we evaluated the effects of a select mixture of Lactobacillus johnsonii L531, Bacillus licheniformis BL1721 and Bacillus subtilis BS1715 (LBB-mix) in prevention of Salmonella enterica serovar Infantis infection in a pig model. LBB-mix was orally administered to newly weaned piglets for seven days before S. Infantis challenge. LBB-mix pretreatment ameliorated S. Infantis-induced fever, leukocytosis, growth performance loss, and ileal inflammation. Pre-administration of LBB-mix reduced the number of Salmonella in the feces but increased the number of goblet cells in the ileum. S. Infantis infection resulted in an increase in cell death in the ileum, this increase was attenuated by LBB-mix consumption. Claudin 1 and cleaved caspase-1 expression was decreased in the ileum of pigs challenged with S. Infantis, but not in pigs pretreated with LBB-mix. In conclusion, our data indicate that a select LBB-mix has positive effects on controlling S. Infantis infection via alleviating inflammation and maintaining the intestinal mucosal barrier integrity in pigs.
Enhanced Potential Toxic Metal Removal Using a Novel Hierarchical SiO2–Mg(OH)2 Nanocomposite Derived from Sepiolite
Authors: Yao Qi-Zhi , Yu Sheng-Hui , Zhao Tian-Lei , Qian Fei-Jin , Li Han , Zhou Gen-Tao , Fu Sheng-Quan
Published: May 2019

Clays are widely used as sorbents for heavy metals due to their high specific surface areas, low cost, and ubiquitous occurrence in most soil and sediment environments. However, the low loading capacity for heavy metals is one of their inherent limitations. In this work, a novel SiO2–Mg(OH)2 nanocomposite was successfully prepared via sequential acid–base modification of raw sepiolite. The structural characteristics of the resulting modified samples were characterized by a wide range of techniques including field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and nitrogen physisorption analysis. The results show that a hierarchical nanocomposite constructed by loading the Mg(OH)2 nanosheets onto amorphous SiO2 nanotubes can be successfully prepared, and the nanocomposite has a high surface area (377.3 m2/g) and pore volume (0.96 cm3/g). Batch removal experiments indicate that the nanocomposite exhibits high removal efficiency toward Gd(III), Pb(II), and Cd(II), and their removal capacities were greatly enhanced in comparison with raw sepiolite, due to the synergistic effect of the different components in the hierarchical nanocomposite. This work can provide a novel route toward a hierarchical nanocomposite by using clay minerals as raw material. Taking into account the simplicity of the fabrication route and the high loading capacities for heavy metals, the developed nanocomposite also has great potential applications in water treatment.
A Review of the Classification of Opal with Reference to Recent New Localities
Authors: Curtis Neville J. , Gascooke Jason R. , Johnston Martin R. , Pring Allan
Published: May 2019

Our examination of over 230 worldwide opal samples shows that X-ray diffraction (XRD) remains the best primary method for delineation and classification of opal-A, opal-CT and opal-C, though we found that mid-range infra-red spectroscopy provides an acceptable alternative. Raman, infra-red and nuclear magnetic resonance spectroscopy may also provide additional information to assist in classification and provenance. The corpus of results indicated that the opal-CT group covers a range of structural states and will benefit from further multi-technique analysis. At the one end are the opal-CTs that provide a simple XRD pattern (“simple” opal-CT) that includes Ethiopian play-of-colour samples, which are not opal-A. At the other end of the range are those opal-CTs that give a complex XRD pattern (“complex” opal-CT). The majority of opal-CT samples fall at this end of the range, though some show play-of-colour. Raman spectra provide some correlation. Specimens from new opal finds were examined. Those from Ethiopia, Kazakhstan, Madagascar, Peru, Tanzania and Turkey all proved to be opal-CT. Of the three specimens examined from Indonesian localities, one proved to be opal-A, while a second sample and the play-of-colour opal from West Java was a “simple” Opal-CT. Evidence for two transitional types having characteristics of opal-A and opal-CT, and “simple” opal-CT and opal-C are presented.
Design and Fabrication of Wafer-Level Microlens Array with Moth-Eye Antireflective Nanostructures
Authors: Xie Shuping , Wan Xinjun , Yang Bo , Zhang Wei , Wei Xiaoxiao , Zhuang Songlin
Published: May 2019

Wafer-level packaging (WLP) based camera module production has attracted widespread industrial interest because it offers high production efficiency and compact modules. However, suppressing the surface Fresnel reflection losses is challenging for wafer-level microlens arrays. Traditional dielectric antireflection (AR) coatings can cause wafer warpage and coating fractures during wafer lens coating and reflow. In this paper, we present the fabrication of a multiscale functional structure-based wafer-level lens array incorporating moth-eye nanostructures for AR effects, hundred-micrometer-level aspherical lenses for camera imaging, and a wafer-level substrate for wafer assembly. The proposed fabrication process includes manufacturing a wafer lens array metal mold using ultraprecise machining, chemically generating a nanopore array layer, and replicating the multiscale wafer lens array using ultraviolet nanoimprint lithography. A 50-mm-diameter wafer lens array is fabricated containing 437 accurate aspherical microlenses with diameters of 1.0 mm; each lens surface possesses nanostructures with an average period of ~120 nm. The microlens quality is sufficient for imaging in terms of profile accuracy and roughness. Compared to lenses without AR nanostructures, the transmittance of the fabricated multiscale lens is increased by ~3% under wavelengths of 400–750 nm. This research provides a foundation for the high-throughput and low-cost industrial application of wafer-level arrays with AR nanostructures.
Role of Berry Anthocyanins and Phenolic Acids on Cell Migration and Angiogenesis: An Updated Overview
Authors: Tsakiroglou Panagiotis , VandenAkker Natalie E. , Del Bo’ Cristian , Riso Patrizia , Klimis-Zacas Dorothy
Published: May 2019

Cell migration is a critical process that is highly involved with normal and pathological conditions such as angiogenesis and wound healing. Important members of the RHO GTPase family are capable of controlling cytoskeleton conformation and altering motility characteristics of cells. There is a well-known relationship between small GTPases and the PI3K/AKT pathway. Endothelial cell migration can lead to angiogenesis, which is highly linked to wound healing processes. Phenolics, flavonoids, and anthocyanins are major groups of phytochemicals and are abundant in many natural products. Their antioxidant, antimicrobial, anti-inflammatory, antidiabetic, angiogenenic, neuroprotective, hepatoprotective, and cardioprotective properties have been extensively documented. This comprehensive review focuses on the in vitro and in vivo role of berry extracts and single anthocyanin and phenolic acid compounds on cell migration and angiogenesis. We aim to summarize the most recent published studies focusing on the experimental model, type of berry extract, source, dose/concentration and overall effect(s) of berry extracts, anthocyanins, and phenolic acids on the above processes.
Nutritional Modulation of Immune and Central Nervous System Homeostasis: The Role of Diet in Development of Neuroinflammation and Neurological Disease
Authors: Estrada José Antonio , Contreras Irazú
Published: May 2019

The gut-microbiome-brain axis is now recognized as an essential part in the regulation of systemic metabolism and homeostasis. Accumulating evidence has demonstrated that dietary patterns can influence the development of metabolic alterations and inflammation through the effects of nutrients on a multitude of variables, including microbiome composition, release of microbial products, gastrointestinal signaling molecules, and neurotransmitters. These signaling molecules are, in turn, implicated in the regulation of the immune system, either promoting or inhibiting the production of pro-inflammatory cytokines and the expansion of specific leukocyte subpopulations, such as Th17 and Treg cells, which are relevant in the development of neuroinflammatory and neurodegenerative conditions. Metabolic diseases, like obesity and type 2 diabetes mellitus, are related to inadequate dietary patterns and promote variations in the aforementioned signaling pathways in patients with these conditions, which have been linked to alterations in neurological functions and mental health. Thus, maintenance of adequate dietary patterns should be an essential component of any strategy aiming to prevent neurological pathologies derived from systemic metabolic alterations. The present review summarizes current knowledge on the role of nutrition in the modulation of the immune system and its impact in the development of neuroinflammation and neurological disease.
Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells
Authors: Alsolmei Faten A. , Li Haiwen , Pereira Suzette L. , Krishnan Padmavathy , Johns Paul W. , Siddiqui Rafat A.
Published: May 2019

Preventing muscle wasting in certain chronic diseases including cancer is an ongoing challenge. Studies have shown that polyphenols derived from fruits and vegetables shows promise in reducing muscle loss in cellular and animal models of muscle wasting. We hypothesized that polyphenols derived from plums (Prunus domestica) could have anabolic and anti-catabolic benefits on skeletal muscle. The effects of a polyphenol-enriched plum extract (PE60) were evaluated in vitro on C2C12 and Colon-26 cancer cells. Data were analyzed using a one-way ANOVA and we found that treatment of myocytes with plum extract increased the cell size by ~3-fold (p < 0.05) and stimulated myoblast differentiation by ~2-fold (p < 0.05). Plum extract induced total protein synthesis by ~50% (p < 0.05), reduced serum deprivation-induced total protein degradation by ~30% (p < 0.05), and increased expression of Insulin-Like Growth Factor-1 (IGF-1) by ~2-fold (p < 0.05). Plum extract also reduced tumor necrosis factor α (TNFα)-induced nuclear factor κB (NFκB) activation by 80% (p < 0.05) in A549/NF-κB-luc cells. In addition, plum extract inhibited the growth of Colon-26 cancer cells, and attenuated cytotoxicity in C2C12 myoblasts induced by soluble factors released from Colon-26 cells. In conclusion, our data suggests that plum extract may have pluripotent health benefits on muscle, due to its demonstrated ability to promote myogenesis, stimulate muscle protein synthesis, and inhibit protein degradation. It also appears to protect muscle cell from tumor-induced cytotoxicity.
Mothers’ Vegetable Consumption Behaviors and Preferences as Factors Limiting the Possibility of Increasing Vegetable Consumption in Children in a National Sample of Polish and Romanian Respondents
Authors: Groele Barbara , Głąbska Dominika , Gutkowska Krystyna , Guzek Dominika
Published: May 2019

Increasing the insufficient intake of vegetables in children may be difficult, due to the influence of parents and at-home accessibility. The aim of this study was to analyze the association between self-reported vegetable consumption behaviors and preferences of mothers and the behaviors and preferences of their children, as declared by them. The nationally representative Polish (n = 1200) and Romanian (n = 1157) samples of mothers of children aged 3–10 were obtained using the random quota sampling method, and interviewed for their and their children’s general frequency of consumption and preferences of vegetables in years 2012–2014. A 24 h dietary recall of vegetable consumption was conducted for mothers and their children. Associations were observed for general number of servings consumed per day by mother–child pairs (p < 0.0001; R = 0.6522, R = 0.6573 for Polish and Romanian samples, respectively) and number of types indicated as preferred (p < 0.0001; R = 0.5418, R = 0.5433). The share of children consuming specific vegetables was 33.1–75.3% and 42.6–75.7% while their mothers also consumed, but 0.1–43.2% and 1.2–22.9% while their mothers did not. The share of children preferring specific vegetables was 16.7–74.1% and 15.2–100% when their mother shared the preference, but 1.3–46.9% and 0–38.3% when their mother did not. The mothers’ vegetable consumption behaviors and preferences may be a factor limiting the possibility of increasing vegetable consumption in their children.
Helianthus annuus Seed Extract Affects Weight and Body Composition of Healthy Obese Adults during 12 Weeks of Consumption: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
Authors: Leverrier Aurélie , Daguet David , Calame Wim , Dhoye Pierre , Kodimule Shyam Prasad
Published: May 2019

The aim of this pilot study was to evaluate the effects of a sunflower (Helianthus annuus) seed extract, standardized for 40% chlorogenic acids on weight and body composition of obese adults. Fifty subjects were randomly assigned to sunflower extract or isocaloric placebo groups, receiving respectively 500 mg/day of treatment for 12 weeks. At the end of the intervention, a significant decrease in body weight, Body Mass Index (BMI), and waist circumference was observed, especially for obese female subjects above 30 years. Those changes were associated with modified body composition related to fat mass loss. A decrease in blood cholesterol was also observed, supporting the potential action of sunflower extract on lipid metabolism. It was concluded that consumption of sunflower extract has a beneficial effect on body weight, fat mass, and lipid profile, providing evidence for its use as a natural anti-obesity herbal extract.
Transcriptomic Analysis of MAPK Signaling in NSC-34 Motor Neurons Treated with Vitamin E
Authors: Chiricosta Luigi , Gugliandolo Agnese , Tardiolo Giuseppe , Bramanti Placido , Mazzon Emanuela
Published: May 2019

Vitamin E family is composed of different tocopherols and tocotrienols that are well-known as antioxidants but that exert also non-antioxidant effects. Oxidative stress may be involved in the progression of neurodegenerative disorders including amyotrophic lateral sclerosis (ALS), characterized by motor neuron death. The aim of the study was the evaluation of the changes induced in the transcriptional profile of NSC-34 motor neurons treated with α-tocopherol. In particular, cells were treated for 24 h with 10 µM α-tocopherol, RNA was extracted and transcriptomic analysis was performed using Next Generation Sequencing. Vitamin E treatment modulated MAPK signaling pathway. The evaluation revealed that 34 and 12 genes, respectively belonging to “Classical MAP kinase pathway” and “JNK and p38 MAP kinase pathway”, were involved. In particular, a downregulation of the genes encoding for p38 (Log2 fold change −0.87 and −0.67) and JNK (Log2 fold change −0.16) was found. On the contrary, the gene encoding for ERK showed a higher expression in cells treated with vitamin E (Log2 fold change 0.30). Since p38 and JNK seem more involved in cell death, while ERK in cell survival, the data suggested that vitamin E treatment may exert a protective role in NSC-34 motor neurons. Moreover, Vitamin E treatment reduced the expression of the genes which encode proteins involved in mitophagy. These results indicate that vitamin E may be an efficacious therapy in preventing motor neuron death, opening new strategies for those diseases that involve motor neurons, including ALS.
Natural Dietary Supplementation of Curcumin Protects Mice Brains against Ethanol-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment via Nrf2/TLR4/RAGE Signaling
Authors: Ikram Muhammad , Saeed Kamran , Khan Amjad , Muhammad Tahir , Khan Muhammad , Jo Min , Rehman Shafiq , Kim Myeong
Published: May 2019

The aim of the current study was to explore the underlying neuroprotective mechanisms of curcumin (50 mg/kg, for six weeks) against ethanol (5 mg/kg i.p., for six weeks) induced oxidative stress and inflammation-mediated cognitive dysfunction in mice. According to our findings, ethanol triggered reactive oxygen species (ROS), apoptosis, neuroinflammation, and memory impairment, which were significantly inhibited with the administration of curcumin, as assessed by ROS, lipid peroxidation (LPO), and Nrf2/HO-1 (nuclear factor erythroid 2-related factor 2/Heme-oxygenase-1) expression in the experimental mice brains. Moreover, curcumin regulated the expression of the glial cell markers in ethanol-treated mice brains, as analyzed by the relative expression TLR4 (Toll like Receptor 4), RAGE (Receptor for Advanced Glycations End products), GFAP (Glial fibrillary acidic protein), and Iba-1 (Ionized calcium binding adaptor molecule 1), through Western blot and confocal microscopic analysis. Moreover, our results showed that curcumin downregulated the expression of p-JNK (Phospo c-Jun N-Terminal Kinase), p-NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells), and its downstream targets, as assessed by Western blot and confocal microscopic analysis. Finally, the expression of synaptic proteins and the behavioral results also supported the hypothesis that curcumin may inhibit memory dysfunction and behavioral alterations associated with ethanol intoxication. Altogether, to the best of our knowledge, we believe that curcumin may serve as a potential, promising, and cheaply available neuroprotective compound against ethanol-associated neurodegenerative diseases.