bluuebunny/crossref_metadata_2025 huggingface dataset:
Host-Parasite Interaction between Parasitic Cymothoid Ceratothoa oestroides and Its Host, Farmed European Sea Bass (Dicentrarchus labrax)
Authors: Mladineo Ivona , Hrabar Jerko , Vidjak Olja , Bočina Ivana , Čolak Slavica , Katharios Pantelis , Cascarano Maria Chiara , Keklikoglou Kleoniki , Volpatti Donatella , Beraldo Paola
Published: March 2020

Parasitic isopod Ceratothoa oestroides (Cymothoidea, Isopoda) is a common and generalist buccal cavity-dweller in marine fish, recognised for its detrimental effect in fingerling and juvenile farmed European sea bass (Dicentrarchus labrax). Although distributed throughout the Mediterranean, the isopod provokes acute outbreaks mainly limited to particular endemic areas in Croatia (Adriatic Sea) and Greece (Aegean Sea). While numerous studies have previously evidenced its gross effect on farmed fish (i.e. decreased condition index, slower growth rate, lethargy and mortality), details on the host-parasite interaction are still lacking. Therefore, using a multimethodological approach, we closely examined the structure and appearance of isopod body parts acting in the attachment and feeding (stereomicroscopy, scanning and transmission electron microscopy), and the extent of host tissues damage (histology, immunohistochemistry, micro-computational tomography) induced by parasitation. Interestingly, while hematophagous nature of the parasite has been previously postulated we found no unambiguous data to support this; we observed host tissues fragmentation and extensive hyperplasia at the parasitation site, and no structures indicative of heme detoxifying mechanisms in the parasite gut, or other traces of a blood meal. The bacterial biofilm covering C. oestroides mouthparts and pereopods suggests that the isopod may play a role in conveying secondary pathogens to the infected host, or alternatively, it serves the parasite in normal interaction with its environment.
HPLC–PDA Polyphenolic Quantification, UHPLC–MS Secondary Metabolite Composition, and In Vitro Enzyme Inhibition Potential of Bougainvillea glabra
Authors: Saleem Hammad , Htar Thet Thet , Naidu Rakesh , Anwar Sirajudheen , Zengin Gokhan , Locatelli Marcello , Ahemad Nafees
Published: March 2020

The plants of the Bougainvillea genus are widely explored regarding nutritive and medicinal purposes. In this study, dichloromethane (DCM) and methanol (MeOH) extracts of Bougainvillea glabra (Choisy.) aerial and flower parts were analyzed for high-performance liquid chromatography with photodiode array detection (HPLC–PDA), ultra-high-performance liquid chromatography–mass spectrometry (UHPLC–MS) phytochemical composition, and enzyme inhibition potential against key enzymes involved in diabetes (α-amylase), skin problems (tyrosinase), and inflammatory disorders (lipoxygenase (LOX)). HPLC–PDA quantification revealed the identification of nine different polyphenolics, amongst which both flower extracts were richest. The flower MeOH extract contained the highest amount of catechin (6.31 μg/g), gallic acid (2.39 μg/g), and rutin (1.26 μg/g). However, none of the quantified compounds were detected in the aerial DCM extract. UHPLC–MS analysis of DCM extracts revealed the tentative identification of 27 secondary metabolites, where the most common belonged to terpenoid, alkaloid, and phenolic derivatives. Similarly, for enzyme inhibition, all the extracts presented moderate activity against tyrosinase and α-amylases, whereas, for LOX, both methanolic extracts showed higher percentage inhibition compared with DCM extracts. Based on our findings, B. glabra could be regarded as a perspective starting material for designing novel pharmaceuticals.
Influence of Blanching Time on Moisture, Sugars, Protein, and Processing Recovery of Sweet Corn Kernels
Authors: Szymanek Mariusz , Dziwulska-Hunek Agata , Tanaś Wojciech
Published: March 2020

The objective of this work is to determine the influence of blanching time on moisture content, sugars, protein, and processing recovery (degree of cut corn) of sweet corn kernels. Sweetcorn cobs of the Jubilee variety were blanched in the water at the temperature 85 °C during the period of 2, 4, 6, and 8 min. Non-blanched cobs were used as control samples. Blanched cobs were made subject to a mechanical process of cutting-off the kernels. It was stated that the blanching time has significant statistical influence on the content of moisture, sugars, and protein in kernel as well as on the quantity of the cut-off kernel mass.
Increased Energy Efficiency of a Backward-Feed Multiple-Effect Evaporator Compared with a Forward-Feed Multiple-Effect Evaporator in the Cogeneration System of a Sugar Factory
Authors: Chantasiriwan Somchart
Published: March 2020

The cogeneration system of a sugar factory consists of boiler, steam turbine, and sugar juice evaporation process. The multiple-effect evaporator used for the conventional sugar juice evaporation process is the forward-feed multiple-effect evaporator, in which steam and sugar juice flow in the same direction. The main objective of this paper is to investigate the energy efficiency of the backward-feed multiple-effect evaporator, in which steam and sugar juice flow in opposite directions, compared with that of the forward-feed multiple-effect evaporator. Mathematical models are developed for both multiple-effect evaporators, and used to compare the performances of two cogeneration systems that use the forward-feed and backward-feed multiple-effect evaporators. The forward-feed multiple-effect evaporator requires extracted steam from a turbine at one pressure, whereas the backward-feed multiple-effect evaporator requires steam extraction at two pressures. Both evaporators have the same total heating surface area, process the same amount of sugar juice, and operate at the optimum conditions. It is shown that the cogeneration system that uses the backward-feed multiple-effect is more energy efficient than the cogeneration system that uses the forward-feed multiple-effect because it yields more power output for the same fuel consumption.
Optimization Strategies for Dockless Bike Sharing Systems via two Algorithms of Closed Queuing Networks
Authors: Fan Rui-Na , Ma Fan-Qi , Li Quan-Lin
Published: March 2020

The dockless bike sharing system (DBSS) has been globally adopted as a sustainable transportation system. Due to the robustness and tractability of the closed queuing network (CQN), it is a well-behaved method to model DBSSs. In this paper, we view DBSSs as CQNs and use the mean value analysis (MVA) algorithm to calculate a small size DBSS and the flow equivalent server (FES) algorithm to calculate the larger size DBSS. This is the first time that the FES algorithm is used to study the DBSS, by which the CQN can be divided into different subnetworks. A parking region and its downlink roads are viewed as a subnetwork, so the computation of CQN is reduced greatly. Based on the computation results of the two algorithms, we propose two optimization functions for determining the optimal fleet size and repositioning flow, respectively. At last, we provide numerical experiments to verify the two algorithms and illustrate the optimal fleet size and repositioning flow. This computation framework can also be used to analyze other on-demand transportation networks.
Data-Driven Modelling of the Complex Interaction between Flocculant Properties and Floc Size and Structure
Authors: Lourenço Anita , Reis Marco S. , Arnold Julien , Rasteiro Maria Graca
Published: March 2020

Polymeric flocculants are widely used due to their ability to efficiently promote flocculation at low dosages. However, fundamental background knowledge about how they act and interact with the substrates is often scarce, or insufficient to infer the best chemical configuration for treating a specific effluent. Inductive, data-driven approaches offer a viable solution, enabling the development of effective solutions for each type of effluent, overcoming the knowledge gap. In this work, we present such an inductive workflow that combines the statistical design of experiments and predictive modelling, and demonstrates its effectiveness in the development of anionic polymeric flocculants for the treatment of a real effluent from the potato crisps manufacturing industry. Based on the results presented, it is possible to conclude that the hydrodynamic diameter, charged fraction and concentration are the parameters with a stronger influence on the characteristics of flocs obtained when using copolymers, while the charged fraction, concentration and hydrophobic content present a stronger influence on the characteristics of flocs obtained using terpolymers containing a hydrophobic monomer.
Impact of Varying Load Conditions and Cooling Energy Comparison of a Double-Inlet Pulse Tube Refrigerator
Authors: Arslan Muhammad , Farooq Muhammad , Naqvi Muhamamd , Sultan Umair , Tahir Zia-ur-Rehman , Nawaz Saad , Waheed Nazim , Naqvi Salman Raza , Ali Qasim , Tariq M. Suleman , Chaudhry Ijaz Ahmad , Anderson John M. , Anukam Anthony
Published: March 2020

Modeling and optimization of a double-inlet pulse tube refrigerator (DIPTR) is very difficult due to its geometry and nature. The objective of this paper was to optimize-DIPTR through experiments with the cold heat exchanger (CHX) along the comparison of cooling load with experimental data using different boundary conditions. To predict its performance, a detailed two-dimensional DIPTR model was developed. A double-drop pulse pipe cooler was used for solving continuity, dynamic and power calculations. External conditions for applicable boundaries include sinusoidal pressure from an end of the tube from a user-defined function and constant temperature or limitations of thermal flux within the outer walls of exchanger walls under colder conditions. The results of the system’s cooling behavior were reported, along with the connection between the mass flow rates, heat distribution along pulse tube and cold-end pressure, the cooler load’s wall temp profile and cooler loads with varied boundary conditions i.e. opening of 20% double-inlet and 40-60% orifice valves, respectively. Different loading conditions of 1 and 5 W were applied on the CHX. At 150 K temperature of the cold-end heat exchanger, a maximum load of 3.7 W was achieved. The results also reveal a strong correlation between computational fluid dynamics modeling results and experimental results of the DIPTR.
A Novel Pigeon-Inspired Optimization Based MPPT Technique for PV Systems
Authors: Tian Ai-Qing , Chu Shu-Chuan , Pan Jeng-Shyang , Liang Yongquan
Published: March 2020

The conventional maximum power point tracking (MPPT) method fails in partially shaded conditions, because multiple peaks may appear on the power–voltage characteristic curve. The Pigeon-Inspired Optimization (PIO) algorithm is a new type of meta-heuristic algorithm. Aiming at this situation, this paper proposes a new type of algorithm that combines a new pigeon population algorithm named Parallel and Compact Pigeon-Inspired Optimization (PCPIO) with MPPT, which can solve the problem that MPPT cannot reach the near global maximum power point. This hybrid algorithm is fast, stable, and capable of globally optimizing the maximum power point tracking algorithm. Therefore, the purpose of this article is to study the performance of two optimization techniques. The two algorithms are Particle Swarm Algorithm (PSO) and improved pigeon algorithm. This paper first studies the mechanism of multi-peak output characteristics of photovoltaic arrays in complex environments, and then proposes a multi-peak MPPT algorithm based on a combination of an improved pigeon population algorithm and an incremental conductivity method. The improved pigeon algorithm is used to quickly locate near the maximum power point, and then the variable step size incremental method INC (incremental conductance) is used to accurately locate the maximum power point. A simulation was performed on Matlab/Simulink platform. The results prove that the method can achieve fast and accurate optimization under complex environmental conditions, effectively reduce power oscillations, enhance system stability, and achieve better control results.
Unveiling the Innovators—A Glimpse on Sufi-Salafi Polemics
Authors: Fouad Hazim
Published: March 2020

In western public discourse, as well as in parts of academia, Sufism and Salafism are sometimes portrayed as arch enemies in Islam. However, so far, very few studies have analyzed in detail the polemics between Sufis and Salafis in a western setting. This article tries to fill this gap by providing a snapshot of the critique of Salafism by the Sufi Nāẓimiyya order, as well as the response from the British Salafi spectrum. It will argue that although both protagonists would perceive themselves in the same way as outlined above, in fact both groups are influenced by each other with regard to the benchmark of what constitutes “authentic Islam”, as well as the ways in which arguments are portrayed as legitimately grounded in Islamic thought. These insights may help in better understanding the complexities of contemporary intra-Muslim debates and representations.
From Digital Divide to Social Inclusion: A Tale of Mobile Platform Empowerment in Rural Areas
Authors: Ye Lisha , Yang Huiqin
Published: March 2020

The digital divide in rural areas is an important social issue, especially in developing countries. Although Internet and broadband penetration have increased in the world generally, there are many obstacles for rural China to get access to ICT (Information and Communication Technology) and its services. The mobile platform is regarded as a novel and effective tool to reduce the digital divide. Based on a case of one mobile platform, namely WeCountry in Chinese rural areas, this study illustrates how a mobile platform bridges the digital divide and helps rural areas achieve social inclusion. Results show that: (1) the mobile platform mainly acts on the digital capability divide elimination, and it has to guide and increase users’ usage capability; (2) the mobile platform can empower villagers in structural, psychological, and resource dimensions, achieving political inclusion, social participation inclusion, and economic inclusion; (3) platform providers and government are key organizations during the divide elimination process. This paper concludes with theoretical and practical implications.
Reducing Exchange Rate Risks in International Trade: A Hybrid Forecasting Approach of CEEMDAN and Multilayer LSTM
Authors: Lin Hualing , Sun Qiubi , Chen Sheng-Qun
Published: March 2020

In international trade, it is common practice for multinational companies to use financial market instruments, such as financial derivatives and foreign currency debt, to hedge exchange rate risks. Making accurate predictions and decisions on the direction and magnitude of exchange rate movements is a more direct way to reduce exchange rate risks. However, the traditional time series model has many limitations in forecasting exchange rate, which is nonlinear and nonstationary. In this paper, we propose a new hybrid model of complete ensemble empirical mode decomposition (CEEMDAN) based multilayer long short-term memory (MLSTM) networks. It overcomes the shortcomings of the classic methods. CEEMDAN not only solves the mode mixing problem of empirical mode decomposition (EMD), but also solves the residue noise problem which is included in the reconstructed data of ensemble empirical mode decomposition (EEMD) with less computation cost. MLSTM can learning more complex dependences from exchange rate data than the classic model of time series. A lot of experiments have been conducted to measure the performance of the proposed approach among the exchange rates of British pound, the Australian dollar, and the US dollar. In order to get an objective evaluation, we compared the proposed method with several standard approaches or other hybrid models. The experimental results show that the CEEMDAN-based MLSTM (CEEMDAN–MLSTM) goes on better than some state-of-the-art models in terms of several evaluations.
Deoxynivalenol Induces Inflammation in IPEC-J2 Cells by Activating P38 Mapk And Erk1/2
Authors: Zhang Hua , Deng Xiwen , Zhou Chuang , Wu Wenda , Zhang Haibin
Published: March 2020

Fusarium-derived mycotoxin deoxynivalenol (DON) usually induces diarrhea, vomiting and gastrointestinal inflammation. We studied the cytotoxic effect of DON on porcine small intestinal epithelium using the intestinal porcine epithelial cell line IPEC-J2. We screened out differentially expressed genes (DEGs) using RNA-seq and identified 320 upregulated genes and 160 downregulated genes. The enrichment pathways of these DEGs focused on immune-related pathways. DON induced proinflammatory gene expression, including cytokines, chemokines and other inflammation-related genes. DON increased IL1A, IL6 and TNF-α release and DON activated the phosphorylation of extracellular signal-regulated kinase-1 and-2 (ERK1/2), JUN N-terminal kinase (JNK) and p38 MAPK. A p38 inhibitor attenuated DON-induced IL6, TNF-α, CXCL2, CXCL8, IL12A, IL1A, CCL20, CCL4 and IL15 production, while an ERK1/2 inhibitor had only a small inhibitory effect on IL15 and IL6. An inhibitor of p38 MAPK decreased the release of IL1A, IL6 and TNF-α and an inhibitor of ERK1/2 partly attenuated protein levels of IL6. These data demonstrate that DON induces proinflammatory factor production in IPEC-J2 cells by activating p38 and ERK1/2.
Minimal Concentrations of Deoxynivalenol Reduce Cytokine Production in Individual Lymphocyte Populations in Pigs
Authors: Hlavová Karolina , Štěpánová Hana , Šťastný Kamil , Levá Lenka , Hodkovicová Nikola , Vícenová Monika , Matiašovic Ján , Faldyna Martin
Published: March 2020

Deoxynivalenol (DON) is a mycotoxin frequently found in cereals, and pigs are one of the most sensitive farm species to DON. The aim of this study was to determine the effects of DON in very low doses on peripheral blood mononuclear cells (PBMC) and on particular lymphocyte subpopulations. The cells were exposed to 1, 10 and 100 ng/mL of DON and lymphocyte viability, proliferation, and cytokine (Interleukin (IL)-1β, IL-2, IL-8, IL-17, Interferon (IFN) γ and tumor necrosis factor (TNF) α production were studied. Cells exposed to DON for 5 days in concentrations of 1 and 10 ng/mL showed higher viability compared to control cells. After 18 h of DON (100 ng/mL) exposure, a significantly lower proliferation after mitogen stimulation was observed. In contrast, an increase of spontaneous proliferation induced by DON (100 ng/mL) was detected. After DON exposure, the expression of cytokine genes decreased, with the exception of IL-1β and IL-8, which increased after 18 h exposure to 100 ng/mL of DON. Among lymphocyte subpopulations, helper T-cells and γδ T-cells exhibiting lower production of IL-17, IFNγ and TNFα were most affected by DON exposure (10 ng/mL). These findings show that subclinical doses of DON lead to changes in immune response.
Role of Host and Parasite MIF Cytokines during Leishmania Infection
Authors: Holowka Thomas , Bucala Richard
Published: March 2020

Macrophage migration inhibitory factor (MIF) is an immunoregulatory cytokine that has been extensively characterized in human disease and in mouse models. Its pro-inflammatory functions in mammals includes the retention of tissue macrophages and a unique ability to counteract the immunosuppressive activity of glucocorticoids. MIF also acts as a survival factor by preventing activation-induced apoptosis and by promoting sustained expression of inflammatory factors such as TNF-α and nitric oxide. The pro-inflammatory activity of MIF has been shown to be protective against Leishmania major infection in mouse models of cutaneous disease, however the precise role of this cytokine in human infections is less clear. Moreover, various species of Leishmania produce their own MIF orthologs, and there is evidence that these may drive an inflammatory environment that is detrimental to the host response. Herein the immune response to Leishmania in mouse models and humans will be reviewed, and the properties and activities of mammalian and Leishmania MIF will be integrated into the current understandings in this field. Furthermore, the prospect of targeting Leishmania MIF for therapeutic purposes will be discussed.
Entropy and Energy of Static Spherically Symmetric Black Hole in f(R) Theory
Authors: Zheng Yaoguang , Yang Rong-Jia
Published: March 2020

We consider the new horizon first law in f ( R ) theory. We derive the general formulas to computed the entropy and energy for static spherically symmetric black hole. For applications, some nontrivial solutions in some popular f ( R ) theories are investigated, the entropies and the energies of static spherically symmetric black holes in these models are first calculated.
ТРАНСПЛАНТАЦИЯ ЭМБРИОНОВ КРУПНОГО РОГАТОГО СКОТА НА БАЗЕ ОАО «МОРДОВИЯГОСПЛЕМ»
Authors: LUKONINA О.N. , ROMANOVA T.A. , KIRDYAEV V.M. , ROMANOV A.E.
Published: March 2020

Проведена работа по получению высокоценных племенных бычков. Трансплантацию эмбрионов провели на базе ОАО Мордовиягосплем . В качестве реципиентов отобрали 10 телок помесей 1 поколения черно-пестрой и абердин ангусской пород. После пересадки эмбрионов приживаемость составила 50. Получено 4 бычка, ко- торые находились на подсосе 7 мес. Оценка экономической эффективности использования полученных бычков, проведенная через год после начала их использования в качестве производителей показала, что затраты на получение и выращивание 1 бычка, полученного методом трансплантации, начинают окупаться с первого года получения и реализации от них спермопродукции.

Cattle embryo transplantation was carried out to obtain high-value breeding bull-calves on the basis of Mordoviyagosplem OJSC. As a result of the work, 10 cattle embryos were transplanted and 4 steers were obtained, which will later be used to obtain sperm production. An economic assessment of the work effectiveness is also given. Cattle embryo transplantation was carried out to obtain high-value breeding bull-calves on the basis of Mordoviyagosplem OJSC. As a result of the work, 10 cattle embryos were transplanted and 4 steers were obtained, which will later be used to obtain sperm production. An economic assessment of the work effectiveness is also given.
Measurement and Prediction of Residual Stresses in Low Carbon Steel Pipes Welded Shielded Metal Arc Welding
Authors: Miftin Salah , Mohammed Haidar , Nassar Ameen
Published: March 2020

Welding is carried out with a very complex thermal cycle, which results in irreversible elastic-plastic deformation, and residual stresses in and around fusion zone and heat-affected zone (HAZ). A residual stress due to welding arises from the differential heating of the pipes due to the weld heat source. However, due to the presence of residual stresses in and around the weld zone the strength and life of the component is also reduced. The objective of this work is to measure the welding residual stress in ASTM (A-106 Gr. b) steel pipes with 4" diameter and 6 mm thickness welded manually (SMAW) in three-pass butt joint where shielded metal arc welding process consists of heating, melting and solidification of parent metals and a filler material in localized fusion zone by a transient heat source to form a joint between the parent metals. The welding process will have accrued without preheating and heat treatment. This measuring of residual stress occurs by using hole-drilling strain gauge method according to (ASTM E-873) then the experimental results for residual stresses obtained from welded carbon steel pipes used to provide validation for finite element simulations. The welding process and welding residual stress distribution is calculated by Ansys Finite Element techniques. Theoretical considerations can be assessed by a mechanical model. The overall, there is good agreement between the predicated and measured distributions of residual stress, but the magnitude of predicted stress tend to greater in welding region.
RESULTS OF USING POLYPROPYLENE MESH BY TOTAL EXTRAPERITONEAL LAPAROSCOPIC FOR INGUINAL HERNIAS REPAIR
Authors: Le Quoc Phong , Pham Nhu Hiep , Nguyen Van Lieu , Phan Dinh Tuan Dung , Le Loc
Published: March 2020

Background: Inguinal hernia is a common disease in general surgery, it is treated by total extraperitoneal (TEP) procedure. It is also applicated in the worldwide. Study objectives: The results of use polypropylene mesh by TEP for inguinal hernias. Materials and Method: Prospective study of 93 patients with 102 inguinal hernias hernioplasty by TEP from November 2010 to March 2013 in Hue Central Hospital. Results: The mean age 51.9 ± 19, primary hernia 94.1%, recurrent hernia 5.9%, hematoma 3.2%, seroma 9.5%, wound infection 0%, conversion 6.9%, recurrence rate 1.1%. Conclusions: Hernioplasty by TEP for inguinal hernias are valuable and effective, shorter surgical time, low complications post-operation and low recurrence rate. Keywords: inguinal hernia; TEP
PARAMETERS RELATING TO CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH CKD TREATED BY HEMODIALYSIS
Authors: Vo Tam , Le Phai , Nguyen Huu Vu Quang
Published: March 2020

Objectives: Study the relation of the cardiovascular disease risk factors hypertension, anemia, serum CRP, dyslipidemia, blood calcium-phospho disorders, hypoalbuminemia, hyperglycemia with the time of hemodialysis, residual urine, clearance of creatinin, index of Sokolov-Lyon on the ECG and index of EF on the echocardiography. Material and Method: 80 pateints with chronic kidney disease treated by hemodialysis at Phu Yen Hospital. Results: The inverse correlation of the time of hemodialysis with systolic blood pressure (r = - 0,7175). The inverse correlation of the residual urine time with systolic blood pressure (r = - 0.7076) and the positive correlation with hemoglobin (r =0,2213), The inverse correlation of the clearance of creatinin with systolic blood pressure (r = -0.5768). The positive correlation of the index of Sokolov-Lyon on the ECG with systolic blood pressure (r = 0.4032). The inverse correlation of the index of EF on the echocardiography with systolic blood pressure (r = -0.7379) and the positive correlation with hemoglobin (r = 0,2240). Key words: Chronic kidney disease, hemodialysis, cardiovascular risk factors, hypertension, anemia, CRP
EVALUATION OF CARDIAC MORPHOLOGY AND TEI INDEX BY DOPPLER ECHOCARDIOGRAPHY IN MALE ALCOHOLICS
Authors: Tran Van Anh , Nguyen Thi Thuy Hang
Published: March 2020

Background: The literature has recorded changes in ECG, cardiac morphology in male alcoholics is known by the term "Holiday heart syndrome" with normal heart function. Tei Chuwa devised and published in1995 an index of myocardial performance (the Tei index) that evaluates the LV systolic and diastolic function in combination. To assess cardiac morphology and function through Tei index in male alcoholics, we conducted this study with the following objectives: identify of cardiac morphology and Tei index in male alcoholics, compared with a control group and find out the correlation between left ventricular morphology, Tei index with duration and lifetime intake amount of alcohol. Material and Methods: This study was carried on 100 male subject, 50 alcoholics, mean age 45.50 ± 7.78 and 50 healthy male non-alcoholics with similar age. They are all under echocardiography to measure left ventricular morphology, conventional Doppler Tei index and tissue Doppler Tei indexes. Results: Morphological parameters were significantly greater in alcoholics than in controls: VLTd (9.56 ± 1.64 vs 8.52 ± 0.83), TSTTd (9.29 ± 1.64 vs 8.75 ± 1.10), LVMI (89.82 ± 29.29 vs 77.42 ± 12.67). There were significant differences between the groups of alcoholics and the control subjects with respect to conventional Doppler Tei index and tissue Doppler Tei indexes. The left ventricular mass index correlated with lifetime intake amount of alcohol. conventional Tei index had correlation with duration and lifetime intake amount of alcohol. Conclusions: The alcoholics had left ventricular structural changes, compared to controls. Heart function was evalued by Tei index showed abnormal in alcoholics. Keywords: Alcoholic’s heart, Doppler echocardiography, Tei index.
CLINICAL CHARACTERISTICS AND DETERMINE THE CONCENTRATIONS OF AUTOBODIES AND CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS
Authors: Luu Van Ai , Vo Tam
Published: March 2020

Background: Rheumatoid arthritis is an autoimmune disease with complex pathophysiological mechanisms, in which cytokines plays an important role. Currently, based on the understanding of the cytokines, the treatment of rheumatoid arthritis with biological agents had changed the course of the disease. Objectives: Study the clinical characteristics and determine the concentrations of autoantibodies (RF, Anti CCP) and cytokines (IL-1α,IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, VEGF, IFN-γ, TNF-α, MCP1, EGF) in patients with rheumatoid arthritis, simultaneously, evaluate the correlation between the cytokines concentrations and levels of autoantibodies in patients with rheumatoid arthritis treated at Cho Ray Hospital.Subjects and Methods: Descriptive cross-sectional study conducted in 76 patients with rheumatoid arthritis treated at Cho Ray Hospital form June 2013 to April 2014.Results: - Clinical and laboratory characteristics: The most common clinical manifestations are arthritis (98.7%), symmetry joint damage (96.1%), morning stiffness over 1 hour (90.8%). Subcutaneous nodule is accounted for 3.9%. The most common joints involved in rheumatoid arthritis are wrist (93.4%), MCP and knee (90.8%), PIP (76.3%) and ankle (67.1%), the least common is the hip (14.5%). The percentage of autoantibodies and cytokines: rheumatoid arthritis patients with positive results of anti – CCP is accounted for 86%. rheumatoid arthritis patients with increased IL-1α concentrations is accounted for 40,8%; increased IL-1β concentration in 48.7%; increased IL-2 concentration in 32,9%; increased IL-4 concentration in 86%; increased IL-6 concentration in 100%; increased IL-8 concentration in 39,5%; increased IL-10 concentration in 81,6%; increased VEGF concentration in 51,3%; increased IFN-γ concentration in 67,1%; increased TNF-α concentration in 61,8%; increased MCP1 concentration in 30,3%; increased EGF concentration in 39,43%. The average concentrations of cytolines in rheumatoid arthritis patients is as followings: IL-1α (57.36 ± 196.43), IL-1β (123.77± 532.51), Il-2 (279.93 ± 945.04), IL-4(279.93 ± 945.04), IL-6(91.35 ± 170.52), IL-8(270.84 ± 445.45), IL-10(134.58 ± 496.14), VEGF(638.87 ± 540.18), IFN-γ(136.43 ± 338.68), TNF-α(106.27 ± 265.57), MCP1(292.34 ± 265.52), EGF(152.62 ± 123.64).RF is correlated with IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-10, IFN-γ, and TNF-α. Anti – CCP is correlated with IL-1α, IL-6. Key words: Rheumatoid arthritis, cytokines
The Relationships within the Poecilimon ornatus Group (Orthoptera: Phaneropterinae) Based on the Cytochrome C Oxidase I Gene
Authors: Kociński Maciej
Published: March 2020

The genus Poecilimon includes 142 species divided into 18 groups. It is distributed throughout the Palaearctic area. One of the groups is the Poecilimon ornatus group, in which many closely related taxa have been identified (13 species). Although several searches have
been carried out, the phylogeny and systematics of P. ornatus are only partly resolved. The most dispersed taxon within the group is Poecilimon affinis, having numerous subspecies. Species from the P. ornatus group have been described mainly based on morphological characteristics,
as well as type of song. The aim of this study is to clarify the relationships between species from the P. ornatus group by comparing partial sequences of the cytochrome c oxidase subunit I (COI) mitochondrial gene. The analyses were carried out on 84 specimens from 23 taxa. Bush-crickets
from the P. ornatus group are monophyletic, in contrast to taxa within the P. affinis complex. Not all of the previously described divisions of the group based on morphology, bioacoustics, distribution, and ecology were confirmed.
Public Consortia for the Treatment of Waste: Analysis from the Principle of Systemic Vision
Authors: Calderan Thanabi Bellenzier , Mazzarino Jane Márcia , Turatti Luciana
Published: March 2020

In Brazil, the National Policy on Solid Waste (Law No. 12,305) brought new guidelines for waste management and incorporated into its text principles that were previously only in the doctrine, especially the one that deals with the systemic view, which considers the variables environmental, social, economic, cultural, technological and public health. This article analyzes the advantages and challenges of inter-municipal consortium for the integrated management of domestic solid waste, in the light of the principle of systemic vision, since it presents itself as a possibility of facing the difficulties that present themselves. This is a bibliographical study. It is concluded that public consortia can be a viable and advantageous alternative in the search for joining efforts to solve common problems to meet PNRS requirements since they have advantages in all dimensions related to the principle of systemic vision.
Extraction of the stabilizer from rigid and plasticized PVC
Authors: Dedov A. V. , Chernousova N. V.
Published: March 2020

The eﬃciency of the developed model for predicting the kinetics of the stabilizer extraction from rigid and plasticized polyvinyl chloride was assessed. The model shows high eﬃciency in the predicting the kinetics of the stabilizer extraction from rigid polyvinyl chloride. The extraction of the stabilizer from the plasticized polyvinyl chloride proceeds in two stages and the kinetic dependences do not obey the model equation.
Development of composite materials based on polyamide and complex metal compounds
Authors: Danyushina G. A. , Derlugyan P. D. , Strelnikov V. V. , Ivanova I. V. , Lyubchenko S. N.
Published: March 2020

A method for modifying PA-12 polyamide with solutions of coordination metal compounds synthesized at the Southern Federal University is proposed. The eﬀect of these additives on the performance and structure of the material being developed is investigated. The optimal concentrations of additives were determined.
Usage of Lactobacillus rhamnosus as a Probiotic in Sea Bass (Dicentrarchus labrax)
Authors: ÖZTÜRK Fatma , ESENDAL Ömer Memduh
Published: March 2020

Bu çalışmada, levrek balıklarında (Dicentrarchus labrax) probiyotik olarak kullanılan Lactobacillus rhamnosus (ATCC 53103)’un deformasyon oranı, yaşama oranı, ağırlık artışı ve bağırsak mikroflorası üzerine etkisi araştırılmıştır. Bu amaçla, probiyotik etken son konsantrasyonu yetiştirme suyunda 106 kob/ml ve Artemia nauplii kültüründe ise 108 kob/ml olacak şekilde ilave edilmiştir. Bu şekilde probiyotik ilavesi 50. güne kadar devam etmiştir. Bu sürenin sonunda her iki grubun toz yemine 109 kob/g düzeyinde probiyotik ilavesi yapılmıştır. Deneme sonunda larvalardaki deformasyon oranları; yetiştirme suyuna probiyotik ilave edilen grupta %5, Artemia kültürüne ilave edilen grupta %2 ve kontrol grubunda %7 olarak tespit edilmiştir (P
Gender, Class and a Naming Process in the English Long Eighteenth Century: Leicestershire c. 1680-1836
Authors: Postles Dave
Published: March 2020

During the 'long eighteenth century', a novel practice of naming was introduced into England which had a long precedent in some parts of continental Europe. Associated at first with aristocratic status, two 'forenames' were selectively adopted at various levels of English society. How that process occurred is illustrated here through a selective sample of Leicestershire parishes as it varied by the intersections of gender and class.
Tuning radiative heat flows between interior surfaces and human occupants to improve heating and cooling efficiency
Authors: Xu Jin , Raman Aaswath
Published: March 2020

Space heating and cooling in buildings account for nearly 20% of energy use globally. In most buildings this energy is used to maintain the thermal comfort of the building’s human occupants by maintaining the interior air temperature at a particular set point. However, if one could maintain the human occupant’s thermal comfort while decreasing the heating or increasing the cooling set point, dramatic energy savings are possible. Here, we propose and evaluate an untapped degree of freedom in improving building efficiency: dynamically tuning the thermal emissivity of interior building surfaces at long-wave infrared wavelengths to maintain thermal comfort. We show that in cold weather conditions tuning the emissivity of interior walls, floors and ceilings to a low value (0.1) can decrease the set point temperature as much as 7°C, corresponding to an energy saving of nearly 67.7% relative to high emissivity materials (0.9). Conversely, in warm weather, high emissivity interior surfaces result in a 38.5% energy savings relative to low emissivity surfaces, highlighting the need for tunability for maximal year-round efficiency. Our results reveal the remarkable energy savings potential possible by better controlling the ubiquitous flows of heat that surround us in the form of thermal radiation.
PERANCANGAN JADWAL PEMBUATAN WELLHEAD DENGAN MENGGUNAKAN CPM PADA SOFTWARE PRIMAVERA
Authors: Setyabudhi Albertus Laurensius , Sasmito Dedi
Published: March 2020

Pengawasan terhadap aktivitas kegiatan dalam jalur kritis sangat dibutuhkan untuk mengetahui perkembangan kemajuan proyek. Penjadwalan sebelumnya belum menampilkan jalur kritis sehingga pengawasan kurang diperhatikan dan memyebabkan keterlambatan dalam pengiriman. Dengan menggunakan metode work breakdown structure (WBS) yang diaplikasikan melalui software Primavera yang baru diharapkan mampu meningkatkan kinerja perusahaan dalam menentukan penjadwalan produksi. Penerapan jalur kritis dalam penjadwalan dengan Primavera ini mempermudah pengawasan terhadap aktivitas yang masuk didalamnya. Hasil dari penjadwalan tersebut menunjukkan beberapa aktivitas kegiatan dalam jalur kritis yang membutuhkan pengawasan lebih ketat. Semua kegiatan tersebut mencakup pembelian material, proses mesin, inspeksi, perakitan, pengetesan dan pengiriman. Dalam penjadwalan ini, total waktu yang dibutuhkan untuk memproduksi sebuah Wellhead yaitu 17 minggu yaitu mulai dari tanggal 21 Maret dan selesai pada tanggal 18 Juli 2017, sehingga dengan menerapkan jalur kritis ini bisa mengurangi keterlambatan pengiriman.
OPTIMASI PERSEDIAAN PRODUK JASJUS
Authors: Yasra Refdilzon , Yusdinata Zeri , Suriyanto
Published: March 2020

Citra Utama Distribusindoraya merupakan perusahaan memesan produk jasjus Mangga yang digunakan sebagai produk dalam kegiatan perdagangan. Selama.ini peramalan persediaan hanyalah berdasarkan intuisi dari perusahaan, sehingga apabila permintaan meningkat maka perusahaan kekurangan persediaan dan begitu juga sebaliknya, oleh karena itu perlu adanya peramalan yang dihitung berdasarkan pola data masa lalu, penelitian ini menggunakan peramalan metode Moving average.dan Regresi Linear Untuk mampu bersaing di dunia industri, salah satu hal yang harus dilakukan adalah mengefesienkan biaya operasi untuk kesuskesan perusahaan. Penelitian yang dilakukan di PT Citra Utama Distribusindoraya pada hakekatnya bertujuan untuk mengetahui tata cara dalam perencanaan persediaan yang akan di gunakan untuk proses produksi. Untuk mengetahui metode apa yang efesian dalam melakukan analisa pada pengendalian persediaan produk jasjus Mangga di PT. Citra Utama Distribusindoraya, maka penelitian ini dilakukan dengan menerapkan metode persediaan Material Requirement Planning, Dengan menerapkan metode pengendalian persediaan Material Requirement Planning pada pengendalian persediaan produk jasjus Mangga, akan diketahui hasil perhitungan yang menyangkut semua kegiatan dalam persediaan. Dengan adanya sistem yang baik serta penggunaan metode yang benar, maka optimalisasi dari biaya persediaan akan tercapai.
Giant Cells Tumour
Authors: Copete-González Ivan , Ferràs-Tarragó Joan , Angulo-Sánchez Manuel Ángel
Published: March 2020

Background: The first line of treatment of Giant Cells Tumor (GCT) consists in the
curettage and coverage with bone graft. New treatments as Denosumab have shown
great results as adjuvants in its treatment, and is gaining popularity in the
treatment, especially because the high rates of local recurrence after surgery and the
limitations of the technique in very aggressive tumors, or in those located in
complex regions. This monoclonal antibody inhibits Receptor Activator of Nuclear
Factor Kappa Beta Ligand (RANKL) and can only be administered in skeletally
mature patients, so it is contraindicated during pregnancy. There are other adjuvant
therapies to surgery, such as cryotherapy with liquid nitrogen or the phenolization,
which can be equally effective.
Methods: We present the case of a pregnant woman of 28 years old diagnosed with an
aggressive GCT of proximal tibia during the first trimester of pregnancy. On this
occasion, surgical treatment was performed by curettage and high speed milling.
Adjuvant treatment was added with liquid nitrogen and the cavity was filled in with
demineralized bone matrix and hydroxyapatite. Based on our experience and on a
revision of the literature, there are few cases described of the treatment of a GCT in a
woman during the pregnancy.
Results: The patient's symptoms disappeared after the intervention. There have not
been shown signs of recurrence after 10 months of clinical follow-up and simple
radiology controls. The treatment did not produce adverse effects in the fetus during
pregnancy neither breastfeeding.
Conclusions: Indications of Denosumab in the treatment of GCT include unresectable
tumors or those in which its resection leads to high morbidity, as well as tumors in the
spine, sacrum, pelvis and challenging lesions located in the upper and lower extremities.
If we cannot opt for this drug for medical or other reasons, cryotherapy with liquid
nitrogen may be effective in its treatment
Shoulder Septic Arthritis
Authors: Copete-González Ivan , Ferràs-Tarragó Joan , Angulo Sánchez Manuel Ángel
Published: March 2020

Background: Septic arthritis is an emergency in orthopedics. Several mechanisms have been described: hematogenous spread, extension from an adjacent focus and direct inoculation, being the first one the most frequent mechanism. If not handled properly neither early, what can lead to the destruction of the articular cartilage and the production of sequelae. In an incipient case, good results can be got with conservative treatment, but usually surgical management is necessary for the resolution of the process. Material and Methods: We present a case of a 5 year old child who suffered an episode of arthritis after the administration of vaccine against serogroup B Neisseria Meningitidis. Symptoms began 2 hours after vaccination with pain and fever of up to 39ºC. At this moment, arthrocentesis was performed and intravenous antimicrobial therapy was initiated. Results: The evolution was favorable with no need of surgical treatment. Symptoms continued going down after the management with arthrocentesis and intravenous antibiotic treatment, until disappearing completely in a few days. During the follow-up, no signs of recurrence have appeared after 12 months. Conclusions: despite the fact that the hematogenous spread is the most frequent mechanism of establishment of arthritis septic, direct inoculation can justify a case of arthritis after vaccination in the deltoid region. We must be careful during vaccination with bacteria toxoids in the deltoid region, due to the risk of reactive arthritis and its differential diagnosis with septic arthritis. More studies are needed to clarify the diagnoses in the borderline cases, being molecular biology techniques as protein chain reaction a fast and useful tool.
STRUGGLES OF WOMEN – A SOCIAL CLASSIFICATION
Authors: M. Sonkamble Dr. Ramesh
Published: March 2020

Characteristics of women who access the cell for assistance as well as the types of violence they face. Over half the women who sought help from the cell did so in the first five years of abuse. For women who had experienced violence for more than five years, the numbers drop sharply. In nearly 60 percent of cases, women are reporting violence within joint or extended family households. As noted above, over a third of the women seeking help were involved in paid work.
KEAWORDS: Women, Violence, Struggle, Sharpness, Households, Family
XYLOTROPHIC BASIDIOMYCETES OF SMALL-LEAVED FORESTS OF THE KOSTROMA REGION
Authors: Maramokhin E. V.
Published: March 2020

This paper provides an overview of the biology and species diversity of xylotrophic basidiomycetes, as well as the biotopic relationships of xylotroph mycobiota with phytocenoses. Ecological groups of these organisms are considered in connection with substrate specialization and their species similarity in birch and aspen small-leaved forests of different pharmacy. A brief assessment of the influence of the anthropogenic factor on the biological diversity of the represented group of organisms is given. For the first time, the Kostroma region is divided into southern, central, and northern parts to assess species diversity depending on weather, climate, and phytocenotic factors. The data on the study of changes in the degree of integration of mycocenoses of birch and aspen forests within the studied areas of the region are presented. In total, over 60 species of xylotrophic basidiomycetes were found in the small-leaved forests in the region, among which 38 species primarily affected birch forests and 40 species of pathogenic xylotrophic basidiomycetes have tropism for P. tremula. It was established that species belonging to the Coriolaseae family predominate in the species composition of wood-destroying mycobiota; they comprise about 27% of the total species composition in birch forests and about 24% of the species composition in aspen forests.
Интегральная модель оценки компетенций кандидатов в магистратуру (адъюнктуру) образовательных учреждений силовых структур
Authors: Gvozdik M.I. , Utkin O.V.
Published: March 2020

Современный этап научно-технического развития силовых структур требует повышения качества отбора и подготовки кадров, поступающих в магистратуру и адъюнктуру. Важным и действенным инструментом для реализации является объективная оценка, которая предоставляет возможность рационально использовать кадровый потенциал подразделений силовых ведомств, повышая тем самым эффективность и уровень научных исследований, проводимых в образовательных учреждениях. В работе помимо общепринятых критериев отбора кадров рассмотрены ряд специфических, таких как, физическая подготовка, психологическая диагностика и другие критерии. В связи с этим в статье введена интегральная модель компетентности кандидата, которая реализована на основе метода сводных показателей с использованием аппарата нечеткой логики первого и второго порядков и метода анализа иерархий. Приведена оценка компетенций кандидатов с использованием программы компьютерной математики MatLab, табличного процессора Microsoft Excel, а так же с помощью авторского программного комплекса Автоматизированная система нечеткого вывода .

The modern stage of scientific and technical development of uniformed agencies requires improving the quality of selection and training of personnel entering the masters and adjunct courses. An important and effective tool for implementation is an objective assessment, which provides an opportunity to rationally use the personnel potential of law enforcement agencies, thereby increasing the efficiency and level of research conducted in educational institutions. In addition to the generally accepted criteria for the selection of personnel, a number of specific criteria, such as physical training, psychological diagnosis and other criteria, are considered. In this regard, the article introduces an integral model of candidate competence, which is implemented on the basis of the method of summary indicators using the apparatus of fuzzy logic of the first and second orders and the method of hierarchy analysis. The assessment of candidates competencies is given using MatLab computer mathematics program, Microsoft Excel spreadsheet processor, as well as using the authors software package Automated fuzzy inference system.