bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlations between non-suicidal self-injury and problematic internet use among Chinese adolescents: a systematic review and meta-analysis
Authors: He Xubin , Yu Qinyao , Peng Jing , Yu Jianghong , Wu Taiying , Qin Yuan , Wang Shengjun , Dong Tiaoxia , Liao Yulong , Hu Chunbi , Yang Ping , Yang Bo
Published: July 2024

Background

Non-Suicidal Self-Injury (NSSI) has continued to be a major issue for public health worldwide, especially among teenagers. Studies have found a certain correlation between NSSI and Problematic Internet Use (PIU). However, this relationship is still unclear among Chinese adolescents, a specific population. Hence, a meta-analysis was carried out on observational studies to explore the connection between NSSI and PIU in Chinese teenagers, aiming to provide more clarity on the correlation.

Methods

To identify the link between NSSI and PIU, we scoured seven digital repositories until November 16, 2023. Employing a random-effects meta-analysis framework, we delved into the association between NSSI and PIU. Additionally, we carried out subgroup evaluations to scrutinize variables including geographical location, age demographics, research methodology, diagnostic instruments, gender, and variables controlled for confounding, like symptoms of depression. For amalgamating data, STATA software (version 16) was deployed.

Results

In this analysis, we included 15 research papers encompassing a collective sample of 137,166 individuals. Our findings revealed a significant positive association between NSSI and PIU within the adolescent population in China, with an Odds Ratio (OR) of 2.02 and a 95% Confidence Interval (CI) ranging from 1.73 to 2.37. Notably, this correlation was markedly stronger in specific subgroups: adolescents from China’s Western regions exhibited an OR of 4.22 (95% CI: 3.44, 5.18); middle school attendees had an OR of 2.09 (95% CI: 1.92, 2.28); those diagnosed with concurrent depression disorders showed an OR of 2.32 (95% CI: 1.98, 2.73); and female adolescents demonstrated an OR of 2.49 (95% CI: 2.26, 2.75), highlighting the nuanced dynamics of this relationship.

Conclusion

This meta-analysis indicates that PIU among adolescents is associated with an increased risk of NSSI. Our findings underscore the importance of targeting specific populations, including those in the western region of China, middle school students, adolescents with comorbid depression disorders, and female adolescents, who may be at higher risk of PIU and subsequently NSSI. These results emphasize the need for tailored interventions and preventive strategies to address these intertwined issues effectively.

Systematic review registration

PROSPERO, identifier CRD42024496579.
The application of metaverse in healthcare
Authors: Wang Yue , Zhu Mengying , Chen Xi , Liu Ruibin , Ge Jinnian , Song Yuxuan , Yu Guilin
Published: July 2024

While metaverse is widely discussed, comprehension of its intricacies remains limited to a select few. Conceptually akin to a three-dimensional embodiment of the Internet, the metaverse facilitates simultaneous existence in both physical and virtual domains. Fundamentally, it embodies a visually immersive virtual environment, striving for authenticity, where individuals engage in real-world activities such as commerce, gaming, social interaction, and leisure pursuits. The global pandemic has accelerated digital innovations across diverse sectors. Beyond strides in telehealth, payment systems, remote monitoring, and secure data exchange, substantial advancements have been achieved in artificial intelligence (AI), virtual reality (VR), augmented reality (AR), and blockchain technologies. Nevertheless, the metaverse, in its nascent stage, continues to evolve, harboring significant potential for revolutionizing healthcare. Through integration with the Internet of Medical Devices, quantum computing, and robotics, the metaverse stands poised to redefine healthcare systems, offering enhancements in surgical precision and therapeutic modalities, thus promising profound transformations within the industry.
Toripalimab plus chemotherapy in the treatment of metastatic triple-negative breast cancer: a cost-effectiveness analysis
Authors: Cai Hongfu , Huang Lisheng , Zheng Zhiwei
Published: July 2024

Objective

This study focuses on assessing the cost-effectiveness of incorporating toripalimab alongside chemotherapy for the treatment of patients diagnosed with metastatic triple-negative breast cancer from the perspective of the Chinese healthcare system.

Methods

A partitioned survival model was constructed to simulate the costs and health outcomes over the lifetime of patients with mTNBC. Clinical data regarding overall survival, progression-free survival, and treatment-related adverse events were derived from the TORCHLIGHT clinical trials. Incremental cost-effectiveness ratio (ICER) were calculated based on the gains in quality-adjusted life-year (QALY). The willingness-to-pay (WTP) threshold was defined as $39,855.79 per QALY. Additionally, sensitivity analyses were conducted to examine the robustness of the model.

Results

The total cost incurred by the group receiving toripalimab was $38,040.62, while the placebo plus chemotherapy was $26,102.07. The utilization of the toripalimab regimen resulted in an increase of 0.74 QALYs and an incremental cost of $11,938.55 compared to the placebo plus chemotherapy group. The ICER was $16,133.18/QALY, indicating that toripalimab plus chemotherapy is a cost-effective strategy according to the WTP threshold. Sensitivity analyses confirmed the robustness of the results.

Conclusion

This study suggests that the addition of toripalimab to chemotherapy for the treatment of mTNBC is a cost-effective strategy. The findings provide valuable evidence to guide decision-making regarding treatment selection for patients with mTNBC in China.
Regional climate response to land cover change in tropical West Africa: a numerical sensitivity experiment with ESA land cover data and advanced WRF-Hydro
Authors: Mortey Eric Mensah , Arnault Joël , Inoussa Maman Maarouhi , Madougou Saïdou , Annor Thompson , Laux Patrick , Dieng Mame Diarra Bousso , Kunstmann Harald
Published: July 2024

The response of regional climate models (RCMs) to different input land cover information is complex and uncertain. Several studies by the regional climate modeling community have investigated the potential of land cover data to help understand land-atmosphere interactions at regional and local scales. This study investigates the regional climate response to introducing European Space Agency (ESA) land cover (LC) data into WRF-Hydro. In addition, this study assesses the potential impacts of afforestation and deforestation strategies on regional water and energy fluxes. An extended version of WRF-Hydro that accounts for a two-way river-land water flow to reduce unrealistic peaks in simulated discharge was employed. The two-way river-land flow setup yielded a better NSE and KGE of 0.47 and 0.69, respectively, over the Kulpawn basin compared to the default setup values of −0.34 and 0.2. Two land use/land cover change effects were deduced from synthetic numerical sensitivity experiments mimicking afforestation by closed shrubland expansion and deforestation by cropland expansion. The afforestation experiment yielded approximately 6% more precipitation, 3% more evapotranspiration, 27% more surface runoff, and 16% more underground runoff, while the deforestation by cropland expansion yielded −5% less precipitation, −3% less evapotranspiration, −3% less surface runoff, and − 9% less underground runoff over the Sissili-Kulpawn Basin (SKB). This result suggests that afforestation (deforestation) could increase the flood (drought) risk. Our synthetic numerical experiment mimics the regional water and energy budgets well and can help climate services and decision-makers by quantifying regional climate response to potential land cover changes.
Implementing a scoping review to explore sport officials' mental health
Authors: Carter Tori B. , Gorczynski Paul , Coady Christopher J. , Cunningham Ian J. , Mascarenhas Duncan R. D. , Grant Murray , Sullivan Philip , Webb Tom , Livingston Lori A. , Hancock David J.
Published: July 2024

Introduction

Sport officials are tasked with applying rules, maintaining fairness, and ensuring athlete safety. However, sport officials experience anxiety, burnout, and non-accidental violence, with the incidence of these events increasing worldwide. This has led to rising attrition rates among sport officials, with many sport organizations concerned for their operational capacity. The effects of anxiety, burnout, and non-accidental violence might contribute to or be indicative of sport officials' negative mental health outcomes. To develop a clear understanding of how sport officials' mental health is affected by their occupation, it is necessary to identify the mental health outcomes and predictors they experience, and to what extent. The purpose of this scoping review was to identify and examine the empirical research and policy documents surrounding sport officials' mental health.

Method

One thousand, two hundred six articles were identified across four databases: PubMed, Web of Science, SportDiscus, and PsycINFO. Next, a policy search was conducted on the respective international governing body websites from English-speaking countries for the 60 included sports. Following screening, 18 studies and one policy document met the inclusion criteria for exploring sport officials' mental health.

Results

Participants (N = 7,941) in the studies were mainly European male soccer and basketball referees. Most studies utilized quantitative inquiry (n = 15) rather than qualitative methods (n = 2) or framework development (n = 1). The research demonstrated that sport officials frequently experienced negative mental health outcomes and predictors including anxiety, depression, burnout, lower mental health literacy, and high levels of stigmatization towards mental health.

Discussion

These outcomes were influenced by gender/sex, age, and experience. There is a need to explore personal and environmental (including occupational) factors that cause or contribute to sport officials' mental health symptoms and disorders.
Iza Šaunová – Jazyk polský. Pierwszy kompleksowy podręcznik do nauki języka polskiego dla Czechów
Authors: Rusin Dybalska Renata
Published: July 2024

The paper presents an excerpt from the ongoing research on teaching Polish in Czechia. Its main focus is to analyse the Polish language textbook Jazyk polský, published in 1958 and written by Iza Šaunová, a teacher of Polish Studies in Prague. The paper discusses the structure of the publication, its content, and the teaching methods used. The analysis of all these elements leads to the conclusion that we are dealing with the first such publication in Czechia. It was comprehensive, and even today its fragments could still be used successfully in teaching. Thus, the presented textbook and its author provide insight not only into the history of teaching Polish in Czechia, but also into the Czech and Polish relations in the postwar times.
Badanie podsystemu składniowego u dzieci dwu- i wielojęzycznych. Problemy z doborem narzędzia
Authors: Brzeszkiewicz Kamila
Published: July 2024

The paper describes the evaluation of the syntactic subsystem in bilingual and multilingual children. It provides a brief overview of tools designed to assess the syntactic competence in Polish-speaking children, and specifies the syntactic elements that that tools take into account. Subsequently, the author introduces a tool she has elaborated in order to study the syntactic subsystem development in bilingual and multilingual children aged 6-9. The criteria for selecting verbs for the procedure as well as the research method are discussed. Finally, the advantages and disadvantages of the designed procedure are presented, as well as the ways it could prove useful in studying selected phenomena of syntactic subsystem development in children.
The Impact of Heat Stress on the Physiological, Productive, and Reproductive Status of Dairy Cows
Authors: Țogoe Dorin , Mincă Nicoleta Andreea
Published: July 2024

Climate change is a global problem with an important influence on farm animals, so the entire veterinary medical industry is working to combat the effects of heat stress. In recent years, global warming has been correlated with physiological changes in adaptation that lead to a decrease in milk production and quality. We have chosen to study these mechanisms that are based on hormonal imbalances (LH, TSH, and prolactin) and general imbalances (apathy and lack of appetite).
Moisture Impact on Static and Dynamic Modulus of Elasticity in Structural Normal-Weight Concretes
Authors: Domagała Lucyna , Margańska Maria , Miazgowicz Marek
Published: July 2024

In the case of concrete built into a structure, the static secant modulus of elasticity (Ec,s) is often estimated based on its dynamic value (Ed) measured by the ultrasonic pulse velocity method instead of direct tests carried out on drilled cores. Meanwhile, the prevailing equations applied to estimate Ec,s often overlook the impact of concrete moisture. This study aimed to elucidate the moisture impact across two normal-weight structural concretes differing in compressive strength (51.6 and 71.4 MPa). The impact of moisture content was notably more evident only for the weaker concrete, according to dynamic modulus measurements. In other cases, contrary to the literature reports and expectations, this effect turned out to be insignificant. These observations may be explained by two factors: the relatively dense and homogeneous structure of tested concretes and reduced sensitivity of Ec,s measurements to concrete moisture condition compared to Ed measurements obtained using the ultrasonic method. Additionally, established formulas to estimate Ec,s were verified. The obtained modulus results tested under different moisture conditions of normal-weight concretes were also compared with those of lightweight aggregate concretes of identical volume compositions previously obtained in a separate study.
Efficacy of Agricultural Residue-Derived Biochar for Tackling Cadmium Contamination in an Aqueous Solution
Authors: Liu Qinghai , Song Zhengguo , Li Jingwen , Pan Chongshuang , Qiu Weiwen
Published: July 2024

This study aimed to investigate the efficacy of biochar, produced from different agricultural residues varying in lignin and cellulose content and subjected to different pyrolysis temperatures, in removing cadmium ions (Cd (II)) from an aqueous solution. This removal process is crucial for protecting human health and the environment. Specifically, the study focused on the adsorption behaviors of Cd (II) by the biochars made from rice husk biochar (RHB), maize straw biochar (MSB), peanut shell biochar (PSB), cottonseed shell biochar (CHB), and mulberry leaf biochar (MLB), which were prepared at 300 °C and 600 °C. The results indicated that the type of agricultural residue used to produce biochar significantly influenced the adsorption of Cd (II). Notably, mulberry leaf biochar prepared at 300 °C (MLB-300) demonstrated the highest adsorption efficiency, achieving a maximum adsorption capacity of 42.2 mg g−1. Batch adsorption experiments assessed the impact of various factors, including system pH, NO3− concentration, and adsorption duration. The adsorption kinetics were better described by the pseudo-second-order model than the pseudo-first-order model. Moreover, the study found that the lignin content of the biochar plays a major role in determining the adsorption capacity. The surface characteristics of biochar, influenced by the types of agricultural residues and preparation temperature, directly impact its adsorption mechanism and capacity. While biochar produced at 300 °C showed optimal Cd(II) adsorption, those processed at 600 °C were less effective, likely due to the loss of functional groups at higher temperatures.
Restructuring and Hydrogen Evolution on Sub-Nanosized PdxBy Clusters
Authors: Zhang De , Wang Ruijing , Luo Sijia , Wei Guangfeng
Published: July 2024

As a Pt-group element, Pd has been regarded as one of the alternatives to Pt-based catalysts for the hydrogen evolution reaction (HER). Herein, we performed density functional theory (DFT) computations to explore the most stable structures of PdxBy (x = 6, 19, 44), revealed the in situ structural reconstruction of these clusters under acidic conditions, and evaluated their HER activity. We found that the presence of B can prevent underpotential hydrogen adsorption and activate the H atoms on the cluster surface for the HER. The theoretical calculations show that the reaction barrier for the HER on ~1 nm sized Pd44B4 can be as low as 0.36 eV, which is even lower than for the same-sized Pt and Pd2B nanoparticles. The ultra-high HER activity of sub-nanosized PdxBy clusters makes them a potential new and efficient HER electro-catalyst. This study provides new ideas for evaluating and designing novel nanocatalysts based on the structural reconstruction of small-sized nanoparticles in the future.
Comprehensive Comparison of Three Different Medicinal Parts of Eupatorium lindleyanum DC. Using the RRLC-Q-TOF-MS-Based Metabolic Profile and In Vitro Anti-Inflammatory Activity
Authors: Lu Jiaojiao , Zheng Chengbo , Xue Simin , Gao Ye , Chen Guijin , Shan Chenxiao , Ding Ning , Peng Guoping , Li Cunyu , Zheng Yunfeng
Published: July 2024

Eupatorium lindleyanum DC. (EL) is a traditional Chinese herb known for its phlegm-reducing, cough-relieving and asthma-calming properties. It is widely used for treating cough and bronchitis. However, preliminary experiments have revealed wide variations in the composition of its different medicinal parts (flowers, leaves and stems), and the composition and efficacy of its different medicinal parts remain largely underexplored at present. In this study, non-targeted rapid resolution liquid chromatography coupled with a quadruple time-of-flight mass spectrometry (RRLC-Q-TOF-MS)-based metabolomics approach was developed to investigate the differences in the chemical composition of different medicinal parts of EL. We identified or tentatively identified 9 alkaloids, 11 flavonoids, 14 sesquiterpene lactones, 3 diterpenoids and 24 phenolic acids. In addition, heatmap visualization, quantitative analysis by high-performance liquid chromatography (HPLC-PDA) and ultra-high-performance liquid chromatography–triple quadrupole tandem mass spectrometry (UPLC-MS/MS) showed particularly high levels of sesquiterpene lactones, flavonoids and phenolic acids in the flowers, such as eupalinolide A and B and chlorogenic acid, among others. The leaves also contained some flavonoid sesquiterpene lactones and phenolic acids, while the stems were almost absent. The findings of in vitro activity studies indicated that the flowers exhibited a notable inhibitory effect on the release of the inflammatory factors TNF-α and IL-6, surpassing the anti-inflammatory efficacy observed in the leaves. Conversely, the stems demonstrated negligible anti-inflammatory activity. The variations in anti-inflammatory activity among the flowers, leaves and stems of EL can primarily be attributed to the presence of flavonoids, phenolic acids and sesquiterpene lactones in both the flowers and leaves. Additionally, the flowers contain a higher concentration of these active components compared to the leaves. These compounds mediate their anti-inflammatory effects through distinct biochemical pathways. The results of this study are anticipated to provide a scientific basis for the rational and effective utilization of EL resources.
QCL Infrared Spectroscopy Combined with Machine Learning as a Useful Tool for Classifying Acetaminophen Tablets by Brand
Authors: Martínez-Trespalacios José A. , Polo-Herrera Daniel E. , Félix-Massa Tamara Y. , Hernandez-Rivera Samuel P. , Hernandez-Fernandez Joaquín , Colpas-Castillo Fredy , Castro-Suarez John R.
Published: July 2024

The development of new methods of identification of active pharmaceutical ingredients (API) is a subject of paramount importance for research centers, the pharmaceutical industry, and law enforcement agencies. Here, a system for identifying and classifying pharmaceutical tablets containing acetaminophen (AAP) by brand has been developed. In total, 15 tablets of 11 brands for a total of 165 samples were analyzed. Mid-infrared vibrational spectroscopy with multivariate analysis was employed. Quantum cascade lasers (QCLs) were used as mid-infrared sources. IR spectra in the spectral range 980–1600 cm−1 were recorded. Five different classification methods were used. First, a spectral search through correlation indices. Second, machine learning algorithms such as principal component analysis (PCA), support vector classification (SVC), decision tree classifier (DTC), and artificial neural network (ANN) were employed to classify tablets by brands. SNV and first derivative were used as preprocessing to improve the spectral information. Precision, recall, specificity, F1-score, and accuracy were used as criteria to evaluate the best SVC, DEE, and ANN classification models obtained. The IR spectra of the tablets show characteristic vibrational signals of AAP and other APIs present. Spectral classification by spectral search and PCA showed limitations in differentiating between brands, particularly for tablets containing AAP as the only API. Machine learning models, specifically SVC, achieved high accuracy in classifying AAP tablets according to their brand, even for brands containing only AAP.
Transformation of Graphite Recovered from Batteries into Functionalized Graphene-Based Sorbents and Application to Gas Desulfurization
Authors: Fernández-Martínez Rodolfo , Ortiz Isabel , Gómez-Mancebo M. Belén , Alcaraz Lorena , Fernández Manuel , López Félix A. , Rucandio Isabel , Sánchez-Hervás José María
Published: July 2024

The recycling and recovery of value-added secondary raw materials such as spent Zn/C batteries is crucial to reduce the environmental impact of wastes and to achieve cost-effective and sustainable processing technologies. The aim of this work is to fabricate reduced graphene oxide (rGO)-based sorbents with a desulfurization capability using recycled graphite from spent Zn/C batteries as raw material. Recycled graphite was obtained from a black mass recovered from the dismantling of spent batteries by a hydrometallurgical process. Graphene oxide (GO) obtained by the Tour’s method was comparable to that obtained from pure graphite. rGO-based sorbents were prepared by doping obtained GO with NiO and ZnO precursors by a hydrothermal route with a final annealing step. Recycled graphite along with the obtained GO, intermediate (rGO-NiO-ZnO) and final composites (rGO-NiO-ZnO-400) were characterized by Wavelength Dispersive X-ray Fluorescence (WDXRF) and X-ray diffraction (XRD) that corroborated the removal of metal impurities from the starting material as well as the presence of NiO- and ZnO-doped reduced graphene oxide. The performance of the prepared composites was evaluated by sulfidation tests under different conditions. The results revealed that the proposed rGO-NiO-ZnO composite present a desulfurization capability similar to that of commercial sorbents which constitutes a competitive alternative to syngas cleaning.
Rise in Serum 25-Hydroxyvitamin D Levels during the COVID-19 Pandemic
Authors: Durden Witt , Ezaldin Shady , Amos Jessica , Kemper Suzanne , Campbell James
Published: July 2024

With the emergence of the COVID-19 pandemic, the absence of established evidence-based treatment protocols led healthcare professionals and the public to explore experimental treatments, including high doses of vitamin D supplements. This study aimed to assess changes in serum 25-hydroxyvitamin D levels during the pandemic, employing a retrospective cohort analysis of data from Charleston Area Medical Center (CAMC). The study analyzed serum 25-hydroxyvitamin D levels in a cohort of 35,556 patients treated at CAMC in 2019, a representative pre-pandemic period, to 2021, a representative pandemic period. Our findings revealed a significant increase in mean serum 25-hydroxyvitamin D levels as compared with 2019 (37 ± 21 vs. 31 ± 15 ng/mL, p ≤ 0.001). Additionally, in 2021, there were significantly more patients exhibiting serum levels in the highest quintiles, specifically >100 ng/mL (1.6% vs. 0.2%), 75–100 ng/mL (4.6% vs. 1.2%), and 50–75 ng/mL (16.0% vs. 8.4%), p ≤ 0.001. This upsurge suggests increased intake of vitamin D supplements, potentially fueled by widespread discussions that were taking place largely on the internet regarding the efficacy of vitamin D against COVID-19. Our findings underscore the critical need for evidence-based public health messaging, especially during health crises, to prevent unnecessary health risks and ensure patient safety.
Diagnosis of Relapse of Colorectal Adenocarcinoma through CEA Fluctuation
Authors: Fekete Zsolt , Ignat Patricia , Gligor Laura , Todor Nicolae , Muntean Alina-Simona , Gherman Alexandra , Eniu Dan
Published: July 2024

Carcinoembryonic antigen(CEA) is a routine marker employed for follow-up of colorectal tumors. We aimed to determine whether a CEA increase within the normal range can be linked to a risk of recurrence. From the period of 2006–2013 we selected 78 consecutive patients with colorectal cancer, who underwent curative surgery with or without neo-/adjuvant chemo- or radiotherapy and had proper follow-up procedures. For analyzing CEA fluctuation, we used the smallest value of the CEA during follow-up as the reference. With the aid of a Chi-squared test, we have chosen the value of 1.1 ng/mL for significant CEA fluctuation. A total of 43.6% of patients had fluctuations in CEA of at least 1.1 ng/mL, with or without increases above 5 ng/mL. From these, in 79.4% of patients, the increases in CEA were explained either by recurrence (44.1%), adjuvant chemotherapy (20.6%) or benign pathology (14.7%). In 23% of the recurrences, a CEA increase of at least 1.1 ng/mL, but below 5 ng/mL, preceded the clinical relapse by a median of 8 months. Our conclusion is that an increase in CEA levels by at least 1.1 ng/mL within the normal range after curative treatment for colorectal cancer may serve as an early indicator of relapse or could be associated with other pathological conditions.
Integrating Rural Development, Education, and Management: Challenges and Strategies
Authors: Yu Yang , Appiah Desmond , Zulu Bernard , Adu-Poku Kofi Asamoah
Published: July 2024

This review explores the complexities of integrated rural development, education, and management, focusing on the challenges encountered and the strategies employed to address them. Integrating various sectors and disciplines in rural development initiatives presents unique obstacles, including coordination issues, resource constraints, and stakeholder engagement difficulties. By examining the existing literature and case studies, this review identifies key challenges, such as limited institutional capacity, inadequate funding, and the need for multidisciplinary collaboration. Furthermore, it analyzes strategies such as community involvement, capacity building, and innovative technology adoption to overcome these obstacles. The review emphasizes the importance of tailored approaches considering local contexts and empowering rural communities in decision-making processes. This approach is essential for the sustainability of rural areas because it ensures that interventions are context-specific, culturally appropriate, and resource-efficient, ultimately leading to more effective and sustainable outcomes. By understanding and addressing the challenges while implementing effective strategies, integrated rural development, education, and management can lead to sustainable and inclusive development outcomes in rural areas.
Eficácia da estimulação hissiana e septal profunda comparada à estimulação cardíaca convencional: revisão de literatura
Authors: Barreto Teixeira Liliane , Pereira Costa Saulo , Antônio Zullo Sérgio , Santos Guerra Stacciarini Thaís , Fernanda Rodrigues Martinho Fernandes Luciane
Published: July 2024

Introdução: Pacientes com insuficiência cardíaca e doenças do sistema de condução necessitam de dispositivos para monitoramento dos batimentos cardíacos, como marcapassos permanentes, dispositivos de ressincronização cardíaca ou cardiodesfibriladores implantáveis. A estimulação ventricular direita é tradicionalmente o tratamento de escolha. No entanto, estudos demonstraram evidências de dissincronia ventricular, redução da função cardíaca, recorrência de fibrilação atrial e aumento da mortalidade associadas a esta abordagem. Conhecimento dos efeitos adversos das técnicas convencionais justifica a realização de pesquisas para determinar se a estimulação hissiana (EH) é uma técnica que produz maior ativação fisiológica e ventricular mais sincronizada. Objetivo: Avaliar a eficácia da estimulação hissiana comparada à EVD em relação aos parâmetros eletrocardiográficos, ecocardiográficos e clínicos. Material e Métodos: Critérios de elegibilidade seguiram a estratégia PICOS: P – pacientes com indicação de dispositivos cardíacos eletrônicos implantáveis; I – estimulação hissiana; C – estimulação ventricular direita; O – duração do complexo QRS, fração de ejeção, diâmetro ventricular ou classe funcional da New York Heart Association; S – ensaios clínicos controlados randomizados (ECR) e não randomizados. As buscas foram realizadas nas bases Medline via PubMed, Embase, LILACS e Cochrane Library, realizadas em março de 2023 por três revisores independentes. Resultados: Foram incluídos sete ensaios clínicos comparando as técnicas EH versus EVD quanto aos desfechos investigados. Para a duração do complexo QRS, três estudos encontraram resultado significativamente melhor no grupo intervenção. Para fração de ejeção e classe funcional da NYHA, dois estudos apresentaram resultados significativamente melhores no grupo EH. Quanto ao risco de viés, apenas dois apresentaram risco baixo e médio, quatro apresentaram risco alto em um, dois ou três dos itens avaliados. Conclusões: Técnica EH demonstrou superioridade à técnica convencional, entretanto são necessários ECR de maior qualidade metodológica e meta-análises para verificar a eficácia clínica da técnica, envolvendo maior número de pacientes e tempo de seguimento.
Força muscular, funcionalidade e qualidade de vida em pacientes com doença de Parkinson após treinamento resistido de baixo volume: um ensaio clínico randomizado
Authors: Abreu Tatiane Cristina Luz de , Carneiro Juliana Alves
Published: July 2024

Introdução: O treinamento resistido (TR) ou musculação aumenta a força muscular e reduz sintomas motores na doença de Parkinson (DP). Objetivo: Verificar os efeitos do TR de baixo volume na força muscular, performance funcional e qualidade de vida de pacientes com DP leve a moderado. Metodologia: Um ensaio clínico randomizado foi realizado com 15 pacientes com DP de 64,27 ± 7 anos, divididos em: Grupo Controle (GC), n= 6, e Grupo Treinamento Resistido (GTR), n= 9. O GC não realizou exercício. O GTR realizou o TR individualizado, por 8 semanas. Cada treino com 6 exercícios, 2 séries de 10 repetições com carga de 60% a 80% de 10 repetições máximas (RM) e intervalo de descanso de 2 minutos. As avaliações foram: teste de força muscular de 10 RM no supino e leg press; performance funcional no Time Up and Go (TUG) e qualidade de vida pelo Parkinson's Disease Questionnaire-39 (PDQ-39). Na análise dos dados foram utilizados o Qui-quadrado e t de Student, além do t pareado e Wilcoxon com o Statistical Packageof Social Sciences (SPSS, 23.0) e significância de p<0,05. Resultados: Os grupos estavam similares antes da intervenção. Após 8 semanas houve diferença significativa entre GC e GRT, respectivamente: na força muscular no supino (25,83±8,61 kg) (43,33±15,6 kg), p= 0,03; no leg press (40,83±25,58 kg) (97,22±16,22 kg), p<0,001; no TUG (12,70±3,42 segundos) (6,94±1,01 segundos), p<0,001; e no score do QDP-39: (41,88±16,70) (18,09±6,78), p= 0,02. Após 8 semanas, no GC houve piora significativa (p>0,05) da qualidade de vida. No entanto, no GTR houve aumento significativo (p>0,05) da força muscular, da funcionalidade e da qualidade de vida. Conclusão: O TR de baixo volume aumentou a força muscular de membros superiores e inferiores, além de melhorar a performance funcional e a qualidade de vida de pacientes com DP leve a moderado.
Preceptoria e planejamento de ações do residente de enfermagem no tratamento dialítico: relato de experiência de preceptoras em um programa de residência multiprofissional
Authors: Carvalho Andreia Aparecida Henriques , Herculano Maria Aparecida Rosa , Ferreira Leticia de Souza Peyroton
Published: July 2024

Introdução: A reflexão e identificação de fatores limitantes relacionados ao ensino prático em programas de residência multiprofissional é de suma importância para a proposição de intervenções e melhorias. A limitada percepção do preceptor sobre seu papel educativo, a dissociação entre teoria e prática e a inadequação dos processos de supervisão dos residentes são tópicos que devem ser abordados nesse cenário. Objetivo: Compartilhar a experiência das autoras no que tange à organização e execução de um plano de atividades para o residente de enfermagem nos serviços de diálise renal em um Hospital Universitário. Material e Métodos: Trata-se de um relato de experiência sobre uma intervenção realizada pelas autoras, enfermeiras, enquanto preceptoras de dois programas de residência multiprofissional em um Hospital Universitário, onde os residentes transitaram por campos de prática relacionados às Terapias Renais Substitutivas. Relato de Experiência: Foram identificados fatores limitantes dos programas, passíveis de intervenção e aprimoramento da prática cotidiana. As atividades desenvolvidas dizem respeito ao acolhimento e ambiência do novo residente; planejamento das atividades teóricas e práticas do residente, supervisão e direcionamento das ações; e, reflexões acerca da prática avaliativa preconizada pelos programas e em relação àquela que vem sendo utilizada pelas autoras, como a autoavaliação e o feedback imediato. Conclusão: Conclui-se que, a partir das ações realizadas, com delineamento prévio das atividades e envolvimento dos residentes, enfermeiros preceptores, tutores e equipe setorial em geral, percebeu-se maior segurança e proatividade para desenvolver as atribuições programadas, bem como maior estímulo à participação e compartilhamento de observações diárias.
EVALUATION OF THE EPIDEMIOLOGICAL PROFILE OF ACQUIRED SYPHILIS IN BRAZIL (2013 TO 2021): PREVALENCE X CHALLENGES
Authors: Vital Júnior Antonio Carlos , Almeida Maria Clara  Gomes de , Fernandes Pedro Lucas Travassos Ribeiro , Monteiro Shênia Santos , Silva Mikaelly Batista da , Dias Jhonatta Alexandre Brito , Silva Karla Monik Alves da , Pasquali Matheus Augusto de Bittencourt
Published: July 2024

Introduction: Syphilis is a sexually transmitted bacterial infection caused by Treponema pallidum, it is considered one of the most common public health problems in Brazil and the world, and affects around 12 million adults and more than 1 million newborns throughout the world. Objective: To describe the epidemiological profile of acquired syphilis in Brazil from 2013 to 2021. Methods: This is an exploratory, nonprobability, descriptive study. Data were collected from the SINAN database and subsequently tabulated and treated by ANOVA analysis of variance. Results: It was found that between the years 2013 to 2021, there was a significant increase in the number of reported cases of acquired syphilis in Brazil, increasing from 39,315 cases in 2013 to 152,915 cases in 2019. To this end, the average annual number of notified cases was over 6,9307 ± 4,5571, with the Southeast region having the highest incidence of the disease (427,615 cases). Conclusion: It is concluded that syphilis is a public health problem of great importance, of which there must be better and more effective prophylactic measures to combat the spread and elimination of the disease.
Evolução farmacêutica: implementação em um hospital universitário com a utilização de prontuário eletrônico
Authors: Trindade Marianne Teixeira , Minateli Milene Machado
Published: July 2024

Objective: The study aimed to build semi-structured models to implement the pharmaceutical evolution in the electronic health records in the pediatrics unit of the University Hospital of the Federal University of Juiz de Fora - Minas Gerais. Methods: The descriptive cross-sectional study was conducted with individuals who were admitted to the non-COVID-19 pediatrics unit from December   01, 2021 to January 31, 2022, and had the pharmacist's clinical activities recorded in their electronic health record. Information was collected from users through the Pharmaceutical History Taking and from the history taking of other professionals, besides the evaluation of prescriptions and recording of interventions suggested by the pharmacist according to the identification of inconsistencies regarding dose, dilutions/diluents, drug interactions, occurrence of adverse reactions, therapeutic duplicity, Y- incompatibilities, and health education. Results: Fourteen semi-structured models based on the SOAP method (Subjective; Objective; Assessment; Plan) were created to    implement the pharmaceutical evolution with record standardization. During the   study period there were 66 hospitalizations. Of these, 45 were eligible and recorded in the electronic document of the pharmaceutical history taking and the result of the assessment of the daily prescriptions, with or without pharmaceutical interventions. Conclusion: The study showed that the electronic health record provides better continuity of care by the pharmacy team within the pediatric sector and broad access to information, in addition to enriching communication and valuing the service of the clinical pharmacist.
Attempts and challenges: experiences with palatal memory plate utilization in children with Down Syndrome – A case report study
Authors: Doro Isabela Afonso , Martins Laís Canêdo , Machado Fernanda Campos , Carrada Camila Faria , Scalioni Flávia Almeida Ribeiro
Published: July 2024

Down syndrome (DS) causes intellectual disability and craniofacial changes due to chromosomal alterations. The Palatal Memory Plate (PPM) is an effective preventive measure for orofacial hypotonicity in DS children. Involving dentists and speech therapists, this multidisciplinary treatment addresses issues like hypotonic tongue, diastasis, and tongue protrusion. The study evaluates PPM use in two DS children: a 3-month-old female with no erupted teeth and a 2-year-old female with erupted teeth. After receiving professional instructions on the use, benefits, and implications of the PPM, the participants underwent digital scanning for the fabrication of the device. Mothers were guided on how to place, remove, and the recommended frequency and duration for daily use of the PPM. Throughout the monitoring period, it was found that the participants were unable to fully adhere to the recommended protocol for PPM use, due to a variety of individual factors such as difficulties in adapting to the device, personal commitments of the families, children's health problems, and the absence of a multidisciplinary team involved in the treatment, which limited the achievement of effective results. Despite deviations from the prescribed protocol, the study emphasizes the need for individual adaptations and multidisciplinary teamwork. Parte superior do formulário
Tailoring interventions to unique patient need in DS orofacial management is crucial for comprehensive and effective care. Additionally, recognizing family challenges also aids healthcare professionals in devising strategies for a more positive experience.
Programa de Residência Pedagógica da Universidade Federal da Bahia
Authors: Silva Rocha Margarida Maria , Costa dos Santos Rosilaine , Franco Grilo Machado Sarah , Julião Santos Suiana
Published: July 2024

Este relato de experiência compreende a participação das autoras-relatoras nas atividades virtuais e remotas, entre dezembro de 2020 e junho de 2021, do Programa de Residência Pedagógica da Universidade Federal da Bahia – Núcleo Letras. A organização deste relato se divide em: introdução, considerações iniciais sobre letramento e gêneros textuais no ensino de língua materna, breves considerações sobre o ensino remoto em um colégio estadual, descrição das atividades desenvolvidas nos períodos de observação e de regência e considerações finais; além das referências. A metodologia utilizada para construção e desenvolvimento deste relato é texto dissertativo-descritivo, com vistas a relatar os acontecimentos principais ocorridos durante a experiência, de maneira pontual. Constatamos, através deste relato, a relevância e a importância que os programas de residência pedagógica têm no processo de formação docente de licenciandos(as) das diversas universidades públicas brasileiras.
Alfabetização de surdos
Authors: Pohl Sanches Maria Jade , Costa do Bomfim Fernando Russo , Veras Reis Gabriel
Published: July 2024

Este artigo baseou-se na prática com estudantes da Educação de Jovens e Adultos (EJA) em uma Escola de surdo. O objetivo principal da prática pedagógica foi proporcionar aos professores em formação, experiências de alfabetização de alunos surdos. A proposta se alicerçou na intervenção pedagógica, como um método de alfabetização por meio de ateliês (Giordani, 2010). A metodologia desta pesquisa, se desenvolveu a partir de um relato de experiência, com a construção de reflexões sobre as atividades desenvolvidas no processo de criação, implantação e análise dos elementos. O resultado obtido foi uma maior visibilidade dos surdos; sua interculturalidade; relações identitárias e protagonismo surdo sob um viés da alfabetização de modo diferenciado e artístico. Além disso, a prática contribuiu para a busca de estratégias inclusivas na formação de professores.
La osa que lame a su osezno neonato o la dualidad persuasión/perfección en la cultura barroca hispana y su contexto emblemático europeo
Authors: García Arranz José Julio
Published: July 2024

Tópico muy extendido en la cultura emblemática de la Edad Moderna, divisa personal de relevantes personajes como el pintor Tiziano Vecellio, la figura de la osa que pacientemente da forma con su lengua a la masa amorfa que, de acuerdo con una extensa tradición literaria, presentan los oseznos al nacer, ha sido ya analizada en diversos contextos y desde distintos puntos de vista. Sin embargo, el asunto aún se encontraba pendiente, a nuestro juicio, de una visión integradora que recompusiera su trayectoria textual y visual desde los orígenes y que valorara su repercusión en la cultura moderna en general, y en el contexto del naturalismo moralizante del Barroco hispano en particular, donde se consolida como imagen del binomio conceptual persuasión/ perfección en los distintos ámbitos en los que el símbolo se aplica.
Innovative Development of Enterprises in the Conditions of Sanctions Pressure
Authors: Ахмадеев А.М.
Published: July 2024

В статье рассмотрены экономические основы инновационного развития предприятий и выделены факторы, которые его обеспечивают. В работе уделяется внимание эффективности становления государственной инновационной политики и указан общественный эффект от внедрения инноваций. Для наглядности проведено сравнение инновационного развития РФ и стран ЕС. Обоснована необходимость привлечения зарубежного опыта инновационных процессов.

The article deals with the economic basis of innovative development of enterprises and highlighted the factors that provide it. The paper focuses on the effectiveness of the formation of the state innovation policy and indicates the social effect of innovation. For visual comparison of innovative development of the Russian Federation and EU countries conducted. The necessity of attracting foreign experience of innovative processes is substantiated.
Innovative Approach to the Organization of Controlling in Terms of Digitalization
Authors: Лабазнова Е.В. , Сердюкова Л.О. , Пахомова А.В. , Баширзаде Р.Р.
Published: July 2024

В статье рассмотрены основные методологические положения инновационного подхода к организации контроллинга, заключающегося в таких ориентированных на рынок и на клиента функционалах, как планирование, анализ, учет. Отражается переосмысление содержания задач контроллера, состоящее в акцентировании внимания на информационной поддержке процесса контроллинга в условиях цифровой трансформации экономики. Новизна подхода к исследованию контроллинга состоит в том, что авторы рассматривают контроллинг как управленческий сервис, предназначенный для внешних по отношению к подразделению контроллинга пользователей и для функциональных подразделений данного предпринимательства. Предложены рекомендации по созданию системы критериев оценки результатов подразделения контроллинга, на условном примере показано их прикладное значение, состоящее в дифференцированном подходе к оценке показателей, отражающих решение внутренних и внешних задач.

The article deals with the main methodological provisions of the innovative approach to the organization of controlling, which consists in market-oriented and customer-oriented functions such as planning, analysis, accounting. The article reflects the rethinking of the content of the tasks of the controller, which consists in focusing on the information support of the controlling process in the conditions of digital transformation of the economy. The novelty of the approach to the study of controlling is that the authors consider controlling as a management service designed for external, in relation to the controlling unit, users, and for the functional units of this enterprise. Recommendations for the creation of a system of criteria for assessing the results of the controlling unit are proposed, their applied value consisting in a differentiated approach to the assessment of indicators reflecting the solution of internal and external problems is shown on a conditional example.
Motivational Human Resources Management
Authors: Гафарова З.Р. , Гареева З.А.
Published: July 2024

В статье проведен обзор существующего множества систем стимулирования, результаты анализа используемых в нефтегазодобыче форм мотивационного управления человеческими ресурсами. Раскрывая сущность действующих систем стимулирования, авторы критически рассматривают возможности их использования на предприятиях нефтяной и газовой промышленности. Также в статье отражены результаты использования различных систем стимулирования на предприятиях.

The article reviewed the existing set of incentive systems, the results of the analysis of existing forms of motivational human resource management. Revealing the essence of incentive systems, the authors critically consider the possibilities of their use in the enterprises of the oil and gas industry. The article also reflects the results of using various incentive systems in enterprises.
Project Financing of Housing Construction Using Crowdfunding Technology
Authors: Садыкова А.И. , Курманова Л.Р.
Published: July 2024

В условиях постепенного перехода от долевого к проектному финансированию жилищного строительства застройщики и банки сталкиваются с проблемой дефицита ресурсов на финансирование всех новостроек и завершение проектов. Механизм проектного финансирования остается не вполне проработанным, что вызывает интерес в рассмотрении иных форм финансирования строительных объектов, в частности, с применением технологии краудфандинга, возможности и преимущества которого рассматриваются в научной статье.

In the context of a gradual transition from equity to project financing of housing construction, developers and banks are faced with the problem of a shortage of resources to finance all new buildings and the completion of projects. The mechanism of project financing remains not fully developed, which causes interest in considering other forms of financing of construction projects, in particular, using the technology of crowdfunding, the possibilities and advantages of which are discussed in a scientific article.