bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of mindfulness-based interventions in the prenatal period on maternal mental health: A quasi experiment
Authors: Vaishnav Smruti B , Mody Sujata K , Sheth Vishal , Asrani Manisha , Ganjiwale Jayshree , Sapre Shilpa , Raithatha Nitin
Published: October 2023

Background:
The mother-baby dyad creates a synergistic being during pregnancy, and women's health at this time is crucial for fetal development and wellness. The time of pregnancy is one of excitement and joy. Unfortunately, it comes with stress and anxiety regarding the baby's health, the delivery method, and any potential complications. These worries can predispose women to developing depression as a result.
Methods:
Using a purposive sampling method, a prospective nonrandomised cohort research study was carried out at the Department of Obstetrics and Gynaecology in 2021–2022. Patients who satisfied the inclusion criteria were enrolled whereas patients who were unable to devote the required time and adherence to various mindfulness interventions were placed in the control group. The researcher administered questionnaires such the FFMQ-15, EPDS, and PSS to each patient. Descriptive analysis was used for the various demographic characteristics that were recorded. The intervention and control groups were compared using independent t tests and chi-square tests for the continuous variables viz-EPDS, PSS, and FFMQ-15.
Results:
The study comprised 36 patients in total; 13 patients were in the control group and 23 patients were a part of the intervention group. The mean ages of the intervention and control groups were 30.78 years and 25.69 years, respectively. A sufficient amount of mindfulness meditation interventions had been practiced by 79% of the patients. Two of the five FFMQ subscales, observing (p=0.001) and describing (p=0.013), indicated a substantial improvement in the mindfulness score in the intervention group. Whereas, acting with awareness, one of the FFMQ's five subscales, saw a substantial increase in the mindfulness score in the control group (p=0.010). There was a statistically significant reduction in the EPDS score in the intervention group before and after the intervention (p=0.007). The reduction in the PSS score after the intervention was statistically significant in the intervention group (p=0.030).
Conclusion: The intervention was perceived as more readily acceptable to women belonging to a higher socio-economic stratum owing to awareness prevalent due to a better education status. The positive impact of mindfulness practices was witnessed owing to the contrast of levels of stress and depression upon enrolment, and their observed decrease after following the various mindfulness interventions.
Citrus aurantium as an economical and massive source of carbon in CQDs synthesis for bandgap tunning in optoelectronic applications
Authors: Gharaati Abdolrasoul , Behaein Saeed
Published: October 2023

As a promising quantum material, carbon quantum dots (CQDs) have been widely applied in almost every optoelectronics device and application but the conventional synthesis methods were not eco-friendly due to the use of toxic and heavy metals. We explored an entirely novel approach, utilizing citrus aurantium (bitter orange) as the carbon source and produced CQDs with 4–6 nanometers in diameter and blue, green, and orange emissions. For the purpose of bandgap tuning, we were able to increase the bandgap energy of CQDs by adding a certain amount of urea and polyethylene glycol to the precursor solution in the synthesis procedure. The bandgap energy of CQDs increased from 2.5 to roughly 3.8 eV. Our approach is thoroughly new which brings about a facile, eco-friendly, and low-cost synthesis method.
Association between the female hormone intake and coronary artery disease in the women: A study based on NHANES 1999-2020
Authors: Qu Shenao , Zhang Zhixuan , Ju Ran , Li Zhuoqun , Leng Jing , Xue Zihan , Han Xuan , Tao Shiran , Lv Yi , Zhang Nana
Published: October 2023

Although many studies have reported the relationship between female hormone intake and the coronary artery disease(CAD) development their association has not been elucidated and defined. Based on data from the Third National Health and Nutrition Examination Survey, this study assessed the relation between female hormone intake and the CAD development in 38745 eligible female participants. Many sociocultural determinants of health (SDOH) factors are significantly related to CAD occurrence and female hormone intake. Stratified analysis of SDOH factors showed that female hormone intake reduces the risk of CAD in women aged ≥ 60 years old. For women who received higher levels of education, female hormone intake is a risk factor for CAD. For women in poverty or wealth, female hormone intake is a risk factor for congestive heart failure and stroke, but it is a protective factor for the four clinical features of CAD for women in middle-income levels. Moreover, for women with menarche at 13–15 years old, menopause at 30–49 years old, and pregnancies 7–9 times, as well as with a low-sugar, low-fat, low-cholesterol diet and proper folic acid intake, female hormone intake have a protective effect on the development of CAD. We conclude that the appropriate female hormone intake plays a protective role in the occurrence of CAD, but it also exerts an adverse effect on CAD under a different SDOH background. It suggested that the patients must be rigorously screened for SODH background in clinical applications of female hormones to exert a protective effect on CAD.
Efficacy and tolerability assessment of a polynucleotide‐based gel for improvement of pattern hair loss Running title: A polynucleotide‐based gel for improvement of pattern hair loss
Authors: Samadi Aniseh , Ayatollahi Azin , Kashani Mansour Nassiri , Zamani Shayan , Firooz Alireza
Published: October 2023

Androgenetic alopecia (AGA) is the leading etiology for scalp hair loss in both genders. Apart from the limited approved pharmaceuticals, there are several suggested nonsurgical-nondrug therapies, including scalp injectables enriched with polynucleotides, however, limited data exists and is mostly limited to one gender. This study evaluates the efficacy and tolerability of a polynucleotide injectable gel quantitatively and quantitively for the treatment of AGA in both genders. Twenty patients with mild to moderate AGA were recruited. A prefilled gel containing 15 mg of polynucleotides was injected for 10 sessions over 4 months {4,2,2,2}. End goals were set at W6, W18, and W24. Evaluations included standard scalp photography scored based on the Global Photographic Review criteria, Likert hair improvement scales for both patient and dermatologist, trichogram, comb test, and adverse reaction. Trial registration number was, IRCT20150101020514N15. The mean age was 37.7 ± 8.1 years. Analysis showed 65%, 77.8%, and 63.2% of patients had slight or moderate improvement in hair growth at W6, W18, and W24, respectively. A statistically significant decrease in hair shedding was observed at all visits. A statically significant increase was observed in the terminal/ vellus hair ratio and the mean value of anagen/ telogen hair ratio at W18 and W24. A statistically significant increase in the mean thickness of hairs was observed at W24. At W6, W18, and W24, 85%, 50%, and 47.4% of participants reported “Improvement” for their hair, respectively. No life-threatening side effects were detected. Mild headache, mild swelling, and maculopapular rash were reported in 2, 2, and 2 patients respectively which were abated with outpatient treatment. This study demonstrated polynucleotide gel injection to be an effective treatment option for decreasing hair shedding and increasing the mean thickness of the hairs with high patient satisfaction and safety profile in male and female AGA.
UV mutagenesis improves growth potential of green algae in a green algae- yeast co-culture system
Authors: Karitani Yukino , Yamada Ryosuke , Matsumoto Takuya , Ogino Hiroyasu
Published: October 2023

It is known that co-cultivation of green algae with heterotrophic microorganisms, such as yeast, improves green algae's growth potential and carbon dioxide fixation, even under low CO2 concentration conditions such as the atmosphere. Introducing mutations into green algae is also expected to enhance their growth potential. In this study, we sought to improve the growth potential of a co-culture system of the green algae Chlamydomonas reinhardtii and the yeast Saccharomyces cerevisiae by introducing mutations into the green algae. Additionally, we performed a transcriptome analysis of the co-culture of the green algae mutant strain with yeast, discussing the interaction between the green algae mutant strain and the yeast. When the green algae mutant strain was co-cultured with yeast, the number of green algae cells reached 152 × 105 cells/mL after 7 days of culture. This count was 2.6 times higher than when the wild-type green algae strain was cultured alone and 1.6 times higher than when the wild-type green algae strain and yeast were co-cultured. The transcriptome analysis also indicated that the primary reason for the increased growth potential of the green algae mutant strain was its enhanced photosynthetic activity and nitrogen utilization efficiency.
Towards Sustainable Stabilization: Sodium Carbonate Tunning the Strength Development of Dredged Sediments Stabilized with Alkali- activated Ground Granulated Blast-furnace Slag
Authors: Ma Ning , Choi Clarence Edward , Zhang Jia-qi
Published: October 2023

Chemical stabilization of dredged sediments presents a promising solution for the reutilization of dredged waste in engineering fills. To promote decarbonization efforts, the use of low-carbon binders, such as alkali-activated ground granulated blast furnace slag (GGBS), emerges as a viable alternative to ordinary Portland cement. Dredged sediments commonly exhibit high water contents (e.g., exceeding 100%), which can compromise the efficacy of alkali-activated GGBS binders in enhancing the strength of these sediments. It has been demonstrated that sodium carbonate (Na2CO3) can potentially accelerate the strength development of alkali-activated GGBS-stabilized sediments. However, the mechanisms on how Na2CO3 influences the strength development of such stabilized sediments remain unclear. This knowledge gap impedes the establishment of a robust scientific foundation for optimizing the mixing design of alkali-activated GGBS binders to effectively stabilize dredged sediments. This study investigates the effects of varying Na2CO3 contents on the strength development of alkali-activated GGBS-stabilized sediments characterized by high water contents. To reveal the mechanisms underlying the effects of Na2CO3 on the strength development of GGBS-stabilized sediments, the reaction products and the pore structures of stabilized sediments are examined by using X-ray diffraction, thermogravimetric analysis, scanning electron microscopy, and mercury intrusion porosimetry techniques. The optimal content of Na2CO3 for attaining the highest 28-day compressive strength of stabilized sediments is determined to be 0.2% by weight. Below this optimal content, the strength of stabilized sediments increases with Na2CO3 content. However, surpassing this optimal content, the increase in Na2CO3 content results in a decrease in the strength of stabilized sediments. The addition of Na2CO3 additive into alkali-activated GGBS-stabilized sediments induces changes in the interactions between clay minerals and reaction products, thereby altering the pore size distribution within the sediments. These modifications in the pore size distribution results in the observed impacts of different Na2CO3 contents on the strength development of stabilized sediments. The revealed mechanisms can provide a scientific basis to optimize the alkali-activated GGBS binders used for the sustainable stabilization of dredged sediments.
City-scale monitoring of antibiotic resistance genes by digital PCR and metagenomics
Authors: Martinez-Garcia Manuel , Maestre-Carballa Lucia , Navarro-López Vicente
Published: October 2023

Background. Anthropogenic activities significantly contribute to the dissemination of antibiotic resistance genes (ARGs), posing a substantial threat to humankind. The development of methods that allow robust ARG surveillance is a long-standing challenge. Here, we use city-scale monitoring of ARGs by using two of the most promising cutting-edge technologies, digital PCR (dPCR) and metagenomics.
Methods. ARG hot-spots were sampled from the water and wastewater distribution systems. Metagenomics was used to provide a broad view of ARG relative abundance and richness in the prokaryotic and viral fractions. From the city-core ARGs in all samples, the worldwide dispersed sul2 and tetW conferring resistance to sulfonamide and tetracycline, respectively, were monitored by digital PCR and metagenomics. To complement, the potential ARG dispersion through airborne aerosols was addressed.
Results. The largest relative overall ARG abundance and richness were detected in the hospital wastewater and the WWTP input (up to »6,000 ARGs/Gb metagenome) with a large fraction of unclassified resistant bacteria. ARG abundance in DNA and RNA viruses was up to three order of magnitude lower compared to prokaryotes. By metagenomics and dPCR, a similar abundance tendency of sul2 and tetW was obtained, with higher abundances in hospital wastewater and WWTP input (»125-225 ARGs/Gb metagenome). dPCR absolute abundances were between 6,000-18,600 copies per ng of sewage DNA (»105-7 copies/mL) and 6.8 copies/mL in seawater near the WWTP discharging point. dPCR data suggest that despite a large amount of gene copies are discharged to nature, marine autochthonous bacteria do not seem to significantly acquire these ARGs. Airborne particle metagenomics showed a broad range of ARGs potentially disseminated with higher abundances at the WWTP (outdoor; 32 ARG hits per Gb and m3) followed by the indoor hospital sample.
Conclusions. dPCR was more sensitive and accurate, while metagenomics provided broader coverage of ARG detection. While desirable, a reliable correlation of dPCR absolute abundance units into metagenomic relative abundance units was not obtained here (r2<0.4) suggesting methodological factors that introduce variability. Evolutionary pressure does not significantly select the targeted ARGs in natural aquatic environments. Finally, non-ventilated and populated environments could represent a human thread in ARG spreading that should be considered within the One-Health perspective.
Clinical efficacy of debridement, antibiotics, and implant retention (DAIR) combined with assembled components replacement in the treatment of acute prosthetic joint infection (PJI) after initial total hip arthroplasty
Authors: Pan Xi’an , Sun Farui , Liu Bingxia , Li Jun , Zhang Yuanjin , Zhang Guofu , Zhou Dingkang
Published: October 2023

Objective: To evaluate the efficacy of debridement, antibiotics, and implant retention (DAIR) combined with the assembled components replacement in the treatment of acute prosthetic joint infection (PJI).
Methods: Twenty-two patients with acute PJI after undergoing initial total hip arthroplasty at the Department of Orthopedics between Jul 2018 and Feb 2022 were enrolled, and treated using DAIR combined with the replacement of assembled components. Infections were assessed based on measurement of white blood cell (WBC), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels at the latest follow-up and before surgery. The performance of hip joint function was evaluated using Harris hip score (HHS), pain relief with visual analog scale (VAS) score, and pre/postoperative conditions analyzed using paired sample t-test.
Results: Twenty-one patients were included in the follow-up analysis. Among them, 20 patients who received treatment with this method achieved successful cure of PJI. The levels of WBC, ESR, and CRP were lower in the last follow-up than those before surgery (WBC: 5.02 ± 0.85 vs. 10.60 ± 1.02, P < 0.05; ESR: 19.10 ± 9.94 vs. 64.90 ± 18.79, P < 0.05; CRP: 5.71 ± 1.65 vs. 55.52 ± 17.80, P < 0.05). HHS scores were higher in the last follow-up relative to before surgery (77.67 ± 7.67 vs. 41.35 ± 7.70, P < 0.05) and VAS scores were lower in the last follow-up than those before surgery (1.57 ± 0.68 vs. 5.86 ± 1.06, P < 0.05).
Conclusions: DAIR combined with the replacement of assembled components can effectively control acute PJI.
Fused Lasso Nearly-Isotonic Signal Approximation in General Dimensions
Authors: Pastukhov Vladimir
Published: October 2023

In this paper we introduce and study fused lasso nearly-isotonic signal approximation, which is a combination of fused lasso and generalized nearly-isotonic regression. We show how these three estimators relate to each other and derive solution to a general problem. Our estimator is computationally feasible and provides a trade-off between monotonicity, block sparsity and goodness-of-fit. Next, we prove that fusion and near-isotonisation in one dimensional case can be applied interchangably, and this step-wise procedure gives the solution to the original optimization problem. This property of the estimator is very important, because it provides a direct way to construct path solution when one of the penalization parameters is fixed. Also, we derive unbiased estimator of degrees of freedom of the estimator.
Nonlinear coexistence phenomenons and FPGA implementation with the hybrid of memristive-memcapacitive hyperchaotic system
Authors: Xu Jingjing , Zhang Xiaohong , Liu Shuling , Moshayedi Ata Jahangir
Published: October 2023

A hybrid circuit based on the magnetic-controlled memristor and charge-controlled memcapacitor is proposed in this paper. The circuit has hyperchaotic behavior in a large scale parameter range. By studying the influence of system parameters and initial conditions on the hybrid circuit, a variety of complex dynamic behaviors can be found: chaos turns into period, spike bursting, chaos turns into spike bursting and so on. Interestingly, different basins of attraction show different shapes. Selecting different basins of attraction positions, the direction of the chaotic attractor changes, but the shape does not change, thus forming a symmetrical coexistence attractor. The coexistence bifurcation diagram and coexistence time-domain waveform diagram under different initial conditions are studied, in the case of positive and negative changes in the initial value v0, the chaotic characteristics of the two cases are consistent. Meanwhile, a series of spectral entropy complexity distributions are analyzed, and find that special shapes are consistent with the attractive basins. Finally, on the platform of Cyclone IV E series, the FPGA main chip of EP4CE115F29C7 is used to complete the hardware implementation of the hybrid memristive-memcapacitive hyperchaotic circuit.
Could “Sub-RPE Illumination” be a prognostic marker for dry AMD?
Authors: Yozgat Zübeyir , Işık Mehmed Uğur , İlgüy Serdar , Ece Berire Şeyma Durmuş , Sabaner Mehmet Cem
Published: October 2023

Purpose
To evaluate the natural history of dry aged related macular degeneration (AMD) with advanced retina pigment epithelium (RPE) analysis and sub-RPE illumination (SRI) data and to determine its relationship with progression.
Methods
Fifty-four eyes of 54 patients with dry AMD who presented with visual symptoms were included in this longitudinal study. SD-OCT scanning was used to evaluate central macular thickness (CMT), average central retinal thickness (CRT), foveal outer nuclear layer (ONL) thickness, ellipsoid zone (EZ) integrity. Advanced RPE analysis software was used for area and volume data at 3mm and 5mm, and SRI assessment at 5mm circles.
Results
This study consisted of 54 patients (29 female) aged 74.72 ± 8.38 years. Area in 3 mm and 5 mm circles (mm²), volume in 3 mm and 5 mm circles (mm³) were found increased at final visit (all, p < 0.001). In SRI data, area in 5 mm circle (mm²) was found to be higher at the final visit (p < 0.001). CMT, CRT, and ONL thickness data were found decreased at final visit (p = 0.014, p < 0.001, p < 0.001, respectively). Baseline and final LogMAR were found decreases inversely as the distance of SRI to the fovea increases (p: 0.03, r = -0.347 and p: 0.04, r= -0.382, respectively). Baseline SRI was higher in patients with disintegrity of EZ at the onset [0.8 (0.1–1.19) vs 0.0 (0–0.1), p: 0.002]. In addition, those with initial disintegrity of EZ had higher final SRI than those without [1.1 (0.3–2.1) vs 0.1 (0.1–0.2), p : 0.038]. There was a significant positive correlation between initial SRI area and final LogMAR (p < 0.001, r = 0.645).
Conclusion
Initial SRI area could predict the risk of vision loss at the end of the 12-month follow-up, and SRI could be considered as a predictor for dry AMD progression.
ACUTE AORTIC DISSECTION TYPE A EXTENDED, COMPLICATED EXTENSIVE STROKE ABOUT A CASE, AND LITERATURE REVIEW
Authors:   Joigny Hospital, Cardiovascular Surgery Department CHU de Dijon-Bourgogne-France, CHU ibn Sina Rabat-Morocco., Bazzout Abdelouahab , Bazzout Innam ,   Joigny Hospital, Cardiovascular Surgery Department CHU de Dijon-Bourgogne-France, CHU ibn Sina Rabat-Morocco., Bozouba Otman ,   Joigny Hospital, Cardiovascular Surgery Department CHU de Dijon-Bourgogne-France, CHU ibn Sina Rabat-Morocco., Morvon Yan ,   Joigny Hospital, Cardiovascular Surgery Department CHU de Dijon-Bourgogne-France, CHU ibn Sina Rabat-Morocco., Tilikette Anis ,   Joigny Hospital, Cardiovascular Surgery Department CHU de Dijon-Bourgogne-France, CHU ibn Sina Rabat-Morocco., Simohamed Jaafari ,   Joigny Hospital, Cardiovascular Surgery Department CHU de Dijon-Bourgogne-France, CHU ibn Sina Rabat-Morocco., Cherti Mohamed ,   Joigny Hospital, Cardiovascular Surgery Department CHU de Dijon-Bourgogne-France, CHU ibn Sina Rabat-Morocco.
Published: October 2023

Patients with acute type A aortic dissection presenting with stroke: should we operate on them?Stroke is a severe complication in the early stages of acute type A aortic dissection and is associated with a dismal prognosis. The surgical treatment of these patients remains controversial. We herein report a challenging clinical presentation of an acute type A aortic dissection revealed by a major brain injury. We further review the literature related to the management of this dreaded association. Recent clinical series show favorable outcomes of early surgical repair in selected patients.
AN ATYPICAL PRESENTATION OF PRIMARY CUTANEOUS FOLLICLE CENTER B-CELL LYMPHOMA
Authors:   Service de Chirurgie Plastique Reconstructrice et des Brules Hopital Militaire Avicenne, Universite cadi Ayyad, Marrakech., Mesfioui Achraf , Arrob Adil ,   Service de Chirurgie Plastique Reconstructrice et des Brules Hopital Militaire Avicenne, Universite cadi Ayyad, Marrakech., Amine Azami Mohamed ,   Service Danatomie Pathologique Hopital Militaire Avicenne, Universite Cadi Ayyad, Marrakech., Tourabi Khalid ,   Service de Chirurgie Plastique Reconstructrice et des Brules Hopital Militaire Avicenne, Universite cadi Ayyad, Marrakech.
Published: October 2023

Background: Primary cutaneous follicle center B-cell lymphoma(PCFCL) is a low-grade lymphoma that affects adults around the age of fifty. We report the case of an atypical presentation. Cas Report:4 years after the complete excision of a lesion above the left eyebrow leading to the diagnosis of a lymphocytic infiltrate in favor of a lymphocytoma. A 55-year-old woman developed bilateral lesions in the ears, treated surgically. One year later, two masses, pseudo tumoral temporal and frontalappeared. After excisional biopsy with immunohistological study and an extension assessment, the diagnosis of PCFCL was retained and polychemotherapy of the CHOP type was undertaken. Discussion :The two localizations, at the level of the ear and fronto-temporal, the antecedent of lymphocytic infiltrate, conferred to our observation its atypical character.
ADHERENCE OF PHYSICIANS PRACTICE TONATIONAL MINISTRY OF HEALTH (MOH) URGENT CARE GUIDELINE IN EASTERN REGION,SAUDI ARABIA
Authors:   Family Medicine Senior Registrar ,Primary Health care / E1 Qatif Sector, Qatif, Eastern Province, KSA., Al-Jishi Ghadeer , AlAskari Zahra ,   Family Medicine Specialist, Primary Health Care / E1 Cluster Qatif Sector, Qatif Eastern Province, KSA., Al Eid Saleha ,   Family Medicine Specialist, Primary Health Care / E1 Cluster,Qatif Sector, Qatif Eastern Province, KSA., AlHashmi Zainab ,   Family Medicine Specialist, Primary Health Care / E1 Cluster Qatif Sector, Qatif Eastern Province, KSA., AL Shaban Taghreed ,   Family Medicine Consultant, Qatif Primary Health Care/ E1 Cluster Qatif Sector, Qatif Eastern Province, KSA., Al Ghareeb Ghadeer ,   Community Medicine Consultant, Primary Health Care / E1 Cluster Qatif Sector, Qatif Eastern Province, KSA.
Published: October 2023

Introduction: In the new era of the Ministry of health transformation, urgent care units (UCCs) were established in primary care. This research evaluated the current practice at the urgent care unit in comparison to the MOH Guideline of Extended Hour Services. Materials and Methods: This is an analytical cross-sectional study that included 293 physicians who worked in UCCs at Primary health care (PHC), Saudi Arabia (SA). The data were collected via a validated online questionnaire distributed to the physicians. Furthermore, UCCs were visited to assess the availability of suitable settings. Univariate and multivariate data analyses were done using the SPSS program. Results: Less than a quarter (23.6%) of UCC physicians were aware of the presence of the National MOH Guideline of extended-hour services. Overall adherence as per physicians perception of the guideline was 48 (24.7%). Increased adherence to Ministry of Health policy as per guidelines by UCC physicians was associated with attending all training courses (OR = 33.72, 95% CI: 2.116-4.920) and awareness of the MOH manual of extended hours services (OR = 2.45, 95% CI: 0.345-1.435). Participants agree on the absence of a clear referral policy to an emergency department and outpatient clinics, 32.3% and 52.3% respectively. Conclusion: UCC physicians training and practices at PHCs did not adequately adhere to the Ministry of Health guidelines. More effort is needed to achieve better outcomes.
COMPARATIVE EVALUATION OF FIBRE REINFORCED COMPOSITE RESIN OVER CONVENTIONAL BAND AND LOOP FOR SPACE MAINTENANCE IN CHILDREN
Authors: M.S Yadukrishnan , Zarina A. Rita , Balachandran Digesh , Dayakar Danu
Published: October 2023

Aim:TocomparetheclinicalsuccessrateofFiberReinforcedCompositeResinspacemaintainerwiththatofConventionalBandandLoopspacemaintainerinchildrenofagegroup6-8years. Methodology:Atotalof60subjects(31girlsand29boys)ofagegroup6to8yearsrequiringspacemaintenanceduetoprematurelossofprimarymolars.ChildrenwhoreceivedFibreReinforcedCompositeResinandBandandLoopspacemaintainerswerecategorizedasGroup1andGroup2respectively.Subjectswererecalledattheendof1st,3rd,and6thmonthsforevaluationofbothtypesofspacemaintainerswhenclinicalsuccessrateofbothtypesofspacemaintainerswereevaluated.Treatmentacceptabilityduringandaftertheprocedurewascheckedusingsix-pointWong-BakerFacesScale. StatisticalAnalysis:ThestatisticalanalysiswasperformedbyusingastatisticalsoftwarepackageSPSSversion25statisticalsoftware.Quantitativevariableswereexpressedasmeanandstandarddeviation.Comparisonofquantitativevariablesbetweenthetwogroupswereanalyzedbyunpairedttest.Qualitativevariableswereexpressedasfrequencyandproportion.Comparisonofqualitativevariablesbetweentwogroupswereanalyzedbychi-squaretest.Apvaluelessthan0.05wasconsideredasstatisticallysignificant Results:Thisstudycomparedthesuccessratesof60spaceMaintainersBandandloopandFRCRsin30childrenintheDepartmentofPediatricDentistryatGovernmentDentalCollege,Thiruvananthapuram.60spacemaintainerswereevaluatedattheendof6months,30bandandloopspacemaintainers wereevaluated,6failedand24weresuccessful.Outof30FRCRspacemaintainers,5failedand25wereconsideredsuccessful.Theclinicalsuccessratewasfoundtobe83.3%forFRCRand81.7%forbandandloop.Thedifferences,however,werenotstatisticallysignificant(P>.05). Conclusion:Althoughstatisticallynosignificantdifferenceinsuccessratesbetweenthesetwotypesofspacemaintainers,FibreReinforcedCompositeResinspacemaintainerhadslightedgeoverBandandloopspacemaintainerintermsofclinicalefficiency.PatientacceptancetowardsthemwerealsofoundFRCRspacemaintainerswasfoundtobeslightlybetterthantothatofbandandloopspacemaintainers.OnasubjectiveopinionmanyofthesubjectspraisedtheestheticqualityofFRCR.TheevidenceobtainedsuggeststhatFRCRisasuitablealternativetoBandandLoopforshorttermspacemaintenanceinyoungchildren.
EPR INVESTIGATIONS OF DPPH AND MN(II)CL2/H2O
Authors:   IB1, Calcutta International School, Anandapur, Kolkata, India-700107., Dey Rajnandini , Petasis Doros ,   Department of Physics, Allegheny College, Meadville, PA-16335, USA.
Published: October 2023

EPR (Electron paramagnetic resonance) spectroscopies of DPPH (DiPhenylPicrylHydrazyl) and Mn(II)Cl2/H2O were carried out at different temperatures and the spectra were analyzed using EPR theory and spectroscopic techniques. The g-values and hyperfine constants were determined from the spectra and were compared to previously established data in other experiments in this field and thus analyzed.
BODY INDICES AND RATIO-TYPE DETERMINANTS OF PERFORMANCE POTENTIALS OF THE BANGLADESHI ADOLESCENT MALEATHLETES
Authors:   Associate Professor, Department of Statistics, University of Chittagong, Bangladesh and Ph.D. Fellow, Department of Statistics, University of Rajshahi, Bangladesh., Rakibul Mawla A.H.M. , Abdul Khalek Md. ,   Professor, Department of Statistics, University of Rajshahi, Rajshahi, Bangladesh., Ayub Ali Md. ,   Professor, Department of Statistics, University of Rajshahi, Rajshahi, Bangladesh.
Published: October 2023

The purpose of the present study was to investigate the different indices and ratio-type determinants of the performance potentials (PP) of the Bangladeshi adolescent male athletes. Primary data of size 414 were collected using multi-stage random sampling on PP and different anthropometric variables, and then several indices and ratio variables were calculated. Forward stepwise Ridge regression was applied to find out the most important determinants of PP of the Bangladeshi adolescent male athletes. Satisfying all the test and validity conditions, it was found that BMI (Body Mass Index) was the most important determinant among the considered indices and ratio variables. Other determinants of PP were RI (Rohrers Index), SHIB (Sitting-Height Index of Build) and WsHtR (Waist to Height Ratio). The proposed equation can be applied for enhancing the PP of the athletes by the sport authorities in Bangladesh.
ANALYSING THE ELEMENTS OF AN ISLAMIC NGOS CONSTITUTION IN MALAYSIA
Authors:   Senior Lecturer, Centre for Syariah Studies, Universiti Kebangsaan Malaysia., Abdul Manap Norhoneydayatie , Aina Abdulah Nur ,   Senior Lecturer, Faculty of Syariah and Law, Universiti Sains Islam Malaysia.
Published: October 2023

Islamic non-governmental organizations (NGOs) in Malaysia are social organizations that play a vital role in various social activities, either domestically or internationally. These organizations are registered under agencies entrusted to register organizations and are subject to the laws and legislation that govern them. Based on the diversity of registration agencies and the legal control over these organizations or NGOs, there are various types of constitutions presented by these organizations or NGOs. Hence, this study analysed the various types of constitutions drawn up by Islamic organizations or NGOs in Malaysia. This qualitative research used a case study design and data were collected from two sources, namely interviews and document analysis involving the organizations constitution. Findings indicated that the organization or NGOs constitution was based on a sample template provided by the registrar of societies. However, the template did not distinguish between an Islamic NGO and a non-Islamic NGO. The study also found six important elements that should be adopted by Islamic NGOs and utilise them as a guide in their daily operations.
FROM AGRICULTURE TO AGRIPRENEURSHIP: AN EXPLORATION INTO THE AGRICULTURAL JOURNEY OF KERALA
Authors:   Research Scholar, Department of Economics, Government College for Women, Thycaud P.O, Thiruvananthapuram., R. Nagasuhasini , V. Umajyothi ,   Associate Professor & Head, Department of Economics, Government College for Women, Thycaud P.O, Thiruvananthapuram.
Published: October 2023

Kerala has a rich agricultural history, an exploration into it is significant. The agricultural sector of the state has been shaped by different phases of development. An analysis of each phase would help understand how the sector was managed to survive from uncertainties and succeed from opportunities. Structural changes and technological revolution have made great impact on the farming sector. The outcome is the gradual development of a new approach to farming. A historical analysis is therefore crucial for understanding the present status of the sector.
INFLUENCE DES PARAMETRES DE REPRODUCTION SUR LA PRODUCTIVITE DES HYBRIDES F2 NAIN X NAIN
Authors:   Universite Felix Houphouet Boigny dAbidjan, UPR de Genetique, UFR Biosciences, 22 B.P. 582 Abidjan22, Cote dIvoire., Ncho Sylvain Djoman , Yacouba Bakayoko ,   Universite. Peleforo Gon Coulibaly de Korhogo, UPR de Genetique,BP 1328 Korhogo., Eric-Blanchard Zadjehi Koffi ,   Universite. Peleforo Gon Coulibaly de Korhogo, UPR de Genetique,BP 1328 Korhogo., KHM Kanh ,   Universite. Peleforo Gon Coulibaly de Korhogo, UPR de Genetique,BP 1328 Korhogo., A. Simon-Pierre NGuetta ,   Universite Felix Houphouet Boigny dAbidjan, UPR de Genetique, UFR Biosciences, 22 B.P. 582 Abidjan22, Cote dIvoire.
Published: October 2023

The objective of this study was to evaluate some production parameters for the identification of elite Nain. Twenty-seven coconut trees, spread over 2 plots, were selected. A control, Malay Yellow Dwarf (NJM), was added to each plot. The study of the relationship between five variables revealed highly significant correlations between them. The multivariate analyses made it possible to identify among the genotypes, the type 7 individuals as being the most efficient. Individuals of type 7 had the highest averages for number of flowers at bag laying (NFP), number of flowers at bag removal (NFE), number of knotted flowers (NFN) and number of nuts harvested (NNR) compared to types 4, 5 and 6. Pollen germination rates in type 1 (Control) individuals were significantly higher than those of the other four types that did not differ significantly between them. The tests for the prediction of the number of nuts harvested indicated that 48.31% of the fluctuations of seed nuts reaching maturity are attributable to the number of female flowers counted at the installation of the bag, that of the female flowers counted at the bag removal and that of the female flowers tied. The predicted values for the number of mature seed nuts are: Nnoirec = -1.12 â€“ 0.007*Nflepose + 0.012*Nflenlev + 0.408*Nflnou +0.014TG. Individuals of type 7 likely to be elite broodstock can be used in programs of genetic improvement of the coconut for better performance.
PREVALENCE OF BEHAVIORAL PROBLEMS AMONG SCHOOL GOING CHILDREN IN SOUTH INDIA
Authors:   Ph.D Scholar, OmayalAchi College of Nursing, affiliated to The Tamil Nadu Dr. MGR Medical University, Puzhal, Chennai-600066., R. Ganesan , J. Hemavathy ,   Ph.D Research Guide & HOD, OmayalAchi College of Nursing, affiliated to The Tamil Nadu Dr. MGR Medical University, Puzhal, Chennai-600066., T. Komalavalli ,   Ph.D Co-Guide & Principal, KarpagaVinayaga College of Nursingaffiliated to The Tamil Nadu Dr. MGR Medical University., P. Jayanthi ,   Vice-Principal, Venkateswara Nursing College affiliated to The Tamil Nadu Dr. MGR Medical University, Chennai.
Published: October 2023

Background: Children can have mental, emotional and behavioural problems that are real, painful and costly. These problems often can lead to development of disorders if neglected which are the sources of stress for children and their families, schools and communities. Aims & Objectives: To assess the prevalence of behavioral problems among school going children. Methodology: Researcher adopted quantitative approach and cross-sectional descriptive study. 1600 school going children screened by child behavior checklist and who fulfilled inclusion and exclusion criteria, were selected as samples by using a non-probability purposive sampling technique. Written informed consent was obtained from the parent and assent obtained from school going children. Results:210(13.13%) school going children had behavioral problems.In experimental group the mean behavioral problem score was 51.83 with SD of 9.75 and in control group the mean behavioral problem score was 53.26 with SD of 11.32. There is a significant difference between experimental and control group behaviour score. Conclusion:The study concluded that majority of the school going children had moderate level of behavioral problems. Regular screening of behavioral problems and early intervention help the school going children to cope and grow in a better way.
EFFECT OF PRELABOUR BMI ON THE MODE OF DELIVERY
Authors: a Dhanvarshini , Kumar Shery Angel Raja
Published: October 2023

Aim:To analyze the effect of Body Mass Index on the Mode of Delivery Design : Cross sectional study Methodology : Sample Size : 100 Patients Inclusion Criteria: Antenatal patients in Active phase of Labour proceeding for delivery Procedure: After ethical comittee approval and written consents from the patients, this comparative cross sectional study was conducted at a Tertiary hospital at CHRI and performed on a total of 100 antental patients who attended the pre labour unit. Their basic information such as age, height, weight, gestational age, and cervical dilatation were noted. Maternal Body Mass Index was noted from pre pregnancy weight from the pregnancy health card.This study is completely a non invasive study Study Duration : 4 months Results : The study population included 100 participants admitted in pre labour unit in a tertiary care hospital. The results obtained showed healthy Body mass Index group had the favourable outcome, whereas the antenatal patients with increased Prepregnancy Body Mass Index had the worst outcome like Cesarean delivery, increased duration of first stage labour, increased duration of second stage labour, APGAR 1to 5, NICU admission, postpartum hemorrhage. Conclusion : This study concludes that Antenatal patients with Increased Body Mass Index have poorer outcomes when compared to Antenatal Patients with normal values of Body Mass Index. This study can be useful in assessing and reducing the poorer materno-fetal outcomes.
DARIER-FERRAND DERMATOFIBROSARCOMA OF THE FACE: TWO CASES REPORT
Authors:   Department of Reconstructive, Plastic and Burn Surgery., Fifatin E. , Idelkheir L. ,   Department of Reconstructive, Plastic and Burn Surgery., Sylla S. ,   Department of Reconstructive, Plastic and Burn Surgery., Sahir M. ,   Department of Reconstructive, Plastic and Burn Surgery., Benlaaguid K. ,   Department of Reconstructive, Plastic and Burn Surgery., Atiqui OE ,   Department of Reconstructive, Plastic and Burn Surgery., Amrani MD ,   Department of Reconstructive, Plastic and Burn Surgery., Benchamkha Y. ,   Department of Reconstructive, Plastic and Burn Surgery.
Published: October 2023

Darier-Ferrand dermatofibrosarcoma or dermatofibrosarcoma protuberans (DFSP) is a cutaneous mesenchymal tumor of intermediate malignancy. It is a rare but not exceptional tumor, accounting for 0.1% of malignant skin tumors. Histological examination is essential for diagnosis. Wide surgical excision is the standard treatment. We report two cases of Darier-Ferrand dermatofibrosarcoma of the face. A wide local excision is the gold-standard treatment, with negative margins of 3â€“5 cm from the tumor edge including the skin, the subcutaneous tissue, and the underlying fascia. However, this is a mutilating surgery, especially for cervicofacial lesions which is the case for our two patients For cervico-facial localizations,some authors advise the Mohs micrographic surgery for its low recurrence rates described. Target adjuvant therapy with imatinib has been shown to reduce tumor size and improve surgical resectability and can be proposed as an option for our patients. However, its unavailability and high-cost limit its use in our context. A combination of conservative excision and adjuvant radiotherapy was reported to reduce the rate of local recurrence and should be also considered by practicians. To improve prognosis, early, codified, multidisciplinary management is essential for this pathology.
INDIAS CONSTITUTIONALISM: AN EXAMINATION OF ITS HISTORICAL DEVELOPMENT AND CURRENT ISSUES
Authors:   Associate Professor and Head Dept of Political Science Rani Parvati Devi College of Arts and Commerce Belagavi, Karnataka., Patil Subhash
Published: October 2023

This paper explores the idea of constitutionalism in India, charting its development over time and evaluating current threats to the countrys constitutional system. The transition of India from colonial oppression to a democratic republic with a strong constitution is an impressive case study in the evolution of constitutions. The paper examines constitutionalisms tenets in the context of India, highlighting its importance in preserving the rule of law, democracy, and human rights. It also draws attention to some of the major issues that Indian constitutionalism is facing in the twenty-first century, including federalism, judicial activism, and minority rights protection. This essay sheds light on the distinct history of constitutionalism in India and its applicability in the modern world.
Sensor placement in water distribution networks using centrality-guided multi-objective optimisation
Authors: Diao Kegong , Emmerich Michael , Lan Jacob , Yevseyeva Iryna , Sitzenfrei Robert
Published: October 2023

This paper introduces a multi-objective optimisation approach for the challenging problem of efficient sensor placement in water distribution networks for contamination detection. An important question is how to identify the minimal number of required sensors without losing the capacity to monitor the system as a whole. In this study, we adapted the NSGA-II multi-objective optimisation method by applying centrality mutation. The approach, with two objectives, namely the minimisation of Expected Time of Detection and maximisation of Detection Network Coverage (which computes the number of detected water contamination events), is tested on a moderate-sized benchmark problem (129 nodes). The resulting Pareto front shows that detection network coverage can improve dramatically by deploying only a few sensors (e.g. increase from one sensor to three sensors). However, after reaching a certain number of sensors (e.g. 20 sensors), the effectiveness of further increasing the number of sensors is not apparent. Further, the results confirm that 40–45 sensors (i.e. 31 − 35% of the total number of nodes) will be sufficient for fully monitoring the benchmark network, i.e. for detection of any contaminant intrusion event no matter where it appears in the network.
Water quality simulation using the WASP model for eutrophication control in a South Indian Reservoir
Authors: K. C. Deepa Varsa , Abdul Rahiman Abdul Wahid , E. Arunbabu , J. Antony Kishoare , N. Priyadharshini
Published: October 2023

The study focused on analysing the eutrophication indicators of the Krishnagiri Reservoir Project (KRP) using the Water Quality Analysis Simulation Program (WASP). The reservoir was divided into six segments to simulate the indicators, and field measurements from 2015 to 2018 were used to calibrate the model while 2019 to 2022 were used to validate it. The results showed that the model predictions were in good agreement with the measured values, indicating the reliability of the model. The study assessed the impact of nutrient loads on dissolved oxygen, nitrate, phosphate, and chlorophyll-a. Four nutrient loading scenarios were simulated, and the most effective scenario (Scenario 4) involved a 75% reduction in nutrient load, which increased the reaeration rate by 1.47% and decreased chlorophyll-a concentrations by 88%. The study concluded that maintaining nitrates below 2.5 mg/L and phosphates below 0.75 mg/L could help restore the KRP reservoir's trophic status from hypereutrophic to mesotrophic. Overall, the study demonstrated the use of the WASP model in developing nutrient loading scenarios to manage reservoir water quality effectively. The findings could help policymakers and managers make informed decisions about reducing nutrient loads and restoring the trophic status of eutrophicated reservoirs.
Increased bio-toxicity of leachates from polyvinyl chloride microplastics during the photo-aging process in the presence of dissolved organic matter
Authors: Chen Lei , Qi Hangyu , Yu Ke , Gao Buhong
Published: October 2023

The pollution caused by microplastics (MPs) has gained global attention due to their potential risks to organisms and human health. The process of photo-aging, which plays a crucial role in the transformation of MPs in aquatic environments, has the potential to influence the ecological risk posed by these particles. Dissolved organic matter (DOM) is a prevalent photosensitizer in surface waters that has been shown to facilitate the transformation of various organic compounds by generating reactive oxygen species under light irradiation. The present study investigated the influence of humic acid (HA), a typical component of DOM, on the photo-aging process of polyvinyl chloride MPs (PVC-MPs), using Fourier transform infrared spectroscopy, as well as assessing the resulting ecological risk through bioassays. The results revealed that the presence of HA enhanced the photo-aging of PVC-MP. Moreover, the leachate exhibited higher acute and genetic toxicity under light irradiation when compared to dark conditions. Notably, the presence of HA significantly increased the toxicity of the leachate, emphasizing the need to consider the impact of DOM when assessing the ecological risk of MPs in surface waters. These findings contribute to a more comprehensive understanding of the potential risks associated with microplastic pollution in natural environments.
A Concise Review on Analytical Methods for Determination of Nilotinib
Authors: Khivansara Ritika , Jadhav Sandhya , Borkar Maheshkumar , Sherje Atul
Published: October 2023

Nilotinib hydrochloride is a tyrosine kinase inhibitor licensed to treat chronic myelogenous
leukemia in patients with the Philadelphia Chromosome (Ph+). Researchers at Novartis
Pharmaceuticals discovered novel inhibitors that are effective against imatinib-resistant BCR-ABL
mutations. As a consequence, Nilotinib was discovered. Several analytical approaches were employed
to address the quantitative as well as qualitative assessment of Nilotinib from diverse biological
and pharmaceutical matrices during the development of Nilotinib. The literature search was conducted
by evaluating publications reporting on nilotinib analytical methodologies from 2006 to 2022.
This review briefly summarizes the drug profile, viz. stereochemistry, mechanism of action,
resistance, pharmacokinetics, pharmacodynamics, side effects, and several analytical techniques used
to assess Nilotinib in dosage form, bulk, and biological fluids. The determination of Nilotinib using
analytical methods is important for therapeutic drug monitoring, optimizing dosage, ensuring safety
and efficacy, and conducting comparative studies. A variety of techniques are gathered and examined,
including spectroscopy, electrophoresis, voltammetry, Raman spectroscopy, differential scanning
calorimetry, X-ray diffraction, chromatography, and hybrid techniques. They are also useful for
studying the pharmacokinetics of the drug. These methods play a crucial role in the effective and
personalized treatment of patients with chronic myeloid leukemia and other conditions where
Nilotinib is used.