bluuebunny/crossref_metadata_2025 huggingface dataset:
Phytochemical screening and In vitro Evaluation of Antibacterial and Antioxidant properties of Moringa oleifera Linn leaf extract
Authors: Gupta Lalan , M Thirumal , Singh S Ankul , Nayabaniya Anant
Published: November 2023

Background: The antibacterial activity and antioxidant properties of the Moringa oleifera leaves belonging to the family Moringaceae grown in Nepal were investigated. The leaves extract exhibited a free radical scavenging capacity. The antimicrobial activity of the leaves extract was assayed against one Gram-positive bacteria (Staphylococcus aureus), three Gram-negative bacteria (Escherichia coli, Klebsiella Pneumoniae, Salmonella typhi). Objective: The main aim of the current study is to evaluate the antibacterial and antioxidant activities of Moringa oleifera leaf extract. Material and Methods: The leaves were collected, authenticated, dried, and extracted with suitable solvent using the Soxhlet apparatus. The antibacterial activity was evaluated in vitro using Agar well diffusion method, and antioxidant activity by the DPPH test method. The antibacterial activity of Moringa oleifera leaf extract was analyzed against Staphylococcus aureus (Gram-positive) and Escherichia coli, Salmonella typhi, Klebsiella pneumoniae (Gram-negative). 200mg/ml, 400mg/ml, 600mg/ml and 800mg/ml concentrations of Moringa oleifera leaf extract and standard drug (Ciprofloxacin 0.005mg/ml) were taken for the study. Results: The ethanolic leaves extract at 800mg/ml and Ciprofloxacin at 0.005mg/ml showed activity against Salmonella typhi with the maximum zone of inhibition of 24±0.15mm and 45±0.25mm, respectively. Klebsiella pneumoniae is resistant to the Ciprofloxacin antibiotic. In antioxidant activity, the maximum percentage of free radical inhibition shown by sample and ascorbic acid (standard) at concentrations of 800mcg/ml was 76.246±1.026% and 98.404±0.702%, respectively. Conclusion: Based on the current findings, Moringa oleifera leaf extract could be used in antibacterial and antioxidant activity
Does the Embryologic Limb Rotation Modify the Distribution of Dermal Collagen and Elastic Fibers in Different Planes of Human Extremities?
Authors: Kumar Naveen , Kumar Pramod , Nayak B Satheesha , Glenda Lewis Melissa , Aithal P Ashwini , Bhaskar Ravi
Published: November 2023

Background: The collagen and the elastic fiber content of the dermis is known to show the asymmetric distribution across the planes of the body region. During the period of limb development, the upper and lower limbs rotate 90 degrees laterally and medially respectively. Objectives: The study aims to check if the limb bud rotation during embryonic development favors the unequal distribution of the dermal connective tissue fiber content distribution. Methods: A total of 240 skin samples from the forearm and thigh regions of adult human cadavers were collected in horizontal and vertical directions from the anatomical and oblique planes. The tissues were processed with tissue-quant analysis. The data were analyzed statistically using SPSS. Results: There were no significant differences in the pattern of distribution of the collagen and elastic fiber contents in the tissues of horizontal and vertical directions from the two planes of forearm and thigh regions. However significant Spearman's correlation was observed in both elements in the thigh region but only the collagen content in the forearm region. Conclusion: The pattern of distribution of connective tissue fibers in the dermis is regulated by the mechanical communications between the cells and their extracellular matrices. Hence, the significant role of embryologic limb rotation in the event of unequal distribution of dermal collagen and elastic fibers in the limb region is to be ruled out.
Assessment of Antibacterial, Cytotoxicity and Wound Healing Influence of Copper Nanoparticles Synthesized using Probiotic Bacteria
Authors: G. Hassan Mervat , El-Waseif Amr A. , Abd El gawad Reem H. , M. Arief Omnia , Abo El-Maaty Sabah A.
Published: November 2023

The present article targeted to biosynthesis and description of copper oxide nanoparticles (CuO NPs) using probiotic isolate and assessment the antibacterial, cytotoxicity of these NPs and its effect on wound heals. The CuO NPs are biosynthesized using probiotic isolate identified as Bacillus cereus. These CuO NPs are characterized using UV, FT-IR, Zeta and TEM. The antibacterial efficiency is assayed by agar plate diffusion protocol. Results assured that the CuO NPs can prevent Staphylococcus aureus jointly Escherichia coli growth. MTT procedure exercised to detect cytotoxicity and wound healing effects. The results revealed that CuO NPs can use as antibacterial agent with non-significant effects on host cells and wound healing.
Development and Validation of Analytical Method by Reverse Phase HPLC for the Estimation of Escitalopram oxalate in Bulk and Dosage form
Authors: Dutt Rohit , Kamboj Sweta , Kamboj Rohit
Published: November 2023

Escitalopram Oxalate (EO) a well-known selective serotonin reuptake inhibitor (SSRI) shows an antidepressant activity. EO function is through raising serotonin levels in the brain, which is a chemical messenger. It regulates depressions of mental and physical symptoms, anxiety and obsessive-compulsive disorders. In this validation method, the HPLC was carried out on Waters -515 HPLC system with an Atlantis Hilic Silica, 5m, C-18 column (4.6250mm) Milford, USA. The identification of sample was done at 238nm, and the duration of retention was found roughly 4.7 minutes for EO. The total run time for the sample analysis was 6 minutes. A concentration ranging from 100-600µg/ml was prepared and the calibration plot revealed a linear relationship. The LOD and LOQ was found to be 111.27g and 337.19g respectively. The proposed method found to have 97 - 105.67% accuracy. The method precision was found within acceptable limits, according to conventional solution repeatability testing. The robustness results were also within acceptable limits. The proposed approach demonstrated outstanding linearity, accuracy, precision, robustness, and LOD and LOQ values that met the requirements. In addition, this new validated method has short run time and a retention time of 4.7 minutes. The present study designed and evaluated a speedy, simple, accurate, precise, and linear HPLC analytical method for EO stability indication. It can be used for quality control examination on a regular basis. The analytical method parameters and mobile phase solvents were found to give high resolution for Escitalopram Oxalate.
In Vivo Pharmacokinetic Studies of Acyclovir Gastro Retentive Mucoadhesive Microspheres Aided by Azadirachta indica Fruit Mucilage
Authors: Naresh Babu Gorantla , M Menaka , Abdul Ahad Hindustan , Veerabomma Sreedhar
Published: November 2023

The study's main goal is to test gastro retentive mucoadhesive Acyclovir (ACR) microspheres for various in vivo characteristics as a follow-up to the work done by Naresh et al (2022). The optimized ACR Azadirachta indica mucoadhesive microspheres (AAMM) were evaluated in vitro using a variety of parameters. Based on previous research findings, the authors used formula-8 (AAMM-8) for in vivo testing. The availability of plasma drugs was tested on six healthy rabbits of both sexes (weighing 2.-2.5kg). By using a parallel design, they were haphazardly parted into two groups of similar size. Later, the study involved HPLC analysis of the drug in the plasma, which required the fabrication of a spiked plasma sample and the development of an analytical procedure (a simple and cost-effective method for ACR).Pharmacokinetic parameters were measured in plasma samples. The study revealed that in vivo animal studies in rabbits showed good levels of ACR. After a single dose of formulation AAMM-8 (8.85mg/kg), the symmetrical mean Cmax values of formulation AAMM-8 (24.36±0.84µg/mL of ACR), were higher than those of ACR. The tmax values of the AAMM-8 were found to be 6 h. The AUC (0-10h) values were observed to be 176.0µg.h/mL, whereas (AUC)0-∞ was observed to be 248.5µg. h/mL. The AUMC readings were observed to be 724.62µg.h/mL. According to the findings, ACR reached systemic circulation faster than pure medication and had acceptable kinetic values.
Experimental Study to Evaluate the Internal Fit between Computer Aided Designing/Computer Aided Manufactured (CAD-CAM) Zirconia Coping and Pressable Ceramic Coping
Authors: Mohamed Mohammed Ashiq , Singaravel Chidambaranathan Ahila , Balasubaramaium Muthukumar
Published: November 2023

Marginal fit of the dental restoration is important to prevent microleakage and periodontal problems so as to avoid secondary caries around the abutment teeth. The purpose of the study was to compare and evaluate the internal fit of copings manufactured using a CAD/CAM-system and laboratory-made heat-pressed ceramics. For this research, typodont mandibular left first molar was prepared about 1.5mm occlusal reduction and 6˚ taper both mesiodistally and buccolingually with shoulder finish line of 1.0mm width to receive all ceramic crown which was duplicated in silicone impressions and the respective working casts were formed using Type IV die stone and the restorations were made by CAD-CAM system for zirconia coping and wax pattern for heat-pressable lithium disilicate ceramics. Total of 20 dies were made and divided into Group I- zirconia copings and Group II - heat pressable lithium disilicate ceramics, in which 10 crowns were made in each group. The crowns were cemented to the respective dies with cyanoacrylate cement using finger pressure. The samples were then sectioned facio-lingually and the three zones measured were 2mm above the marginal finish line in both lingual and buccal side and one in the center of the occlusal surface. The mean horizontal and the vertical internal adaptation discrepancies statistically analyzed using Mann-Whitney test. It was concluded that CAD-CAM milled zirconia copings showed closer adaptation in the axial walls than heat pressed ceramic copings. But in the mid occlusal level where the adaptation was closer in heat pressed ceramic copings than the CAD-CAM milled zirconia copings.
Alternative Therapeutic Nanosponge approach for Treatment of Flesh-Eating Disease- Necrotizing Fasciitis
Authors: C. Tanushree , Verma Rajesh , Sharma Jaya , Sharma Pankaj
Published: November 2023

Clindamycin is a semisynthetic lincosamide antibiotic useful for the treatment of a number of bacterial infections. Clindamycin Phosphate (CP) belongs to BCS class III that is high solubility, low permeability with a topical bioavailability of 4-5%. In the present study permeability is enhanced by targeted drug release formulation of topical Clindamycin Phosphate nanosponges were prepared by Emulsion solvent diffusion method using Ethyl cellulose as release retardant polymer and PVA as surfactant or emulsifier. Nanosponges were prepared by emulsion solvent diffusion method by changing drug polymer ratio (1:0.05, 1:0.1, 1:0.15) and process parameters were optimized using 32 full factorial central design. CP nanosponges were then incorporated into a hydrogel prepared using Carbopol 934. The drug loaded nanosponges were evaluated for physical appearance, drug content, entrapment efficiency, and particle size. Characterization of CP nanosponges were done by and Scanning Electron Microscopy for the formulation. In-vitro release study indicated that the release of CP varied according to the concentration of matrix forming polymer. The best standardized formulation G5 and G6 were further evaluated for microbiological studies. Microbial studies were done using staphylococcus aureus as the strain organism and the activity of the gel against the organism was evaluated by measuring the zone of inhibition. It was also found to be stable for 2 months during its stability studies. Thus, it was concluded that CP can be formulated as Nanosponge hydrogel that can release the drug up to 24hrs with increased permeability and targeted release. Therefore, Topical Clindamycin Phosphate nanosponges prepared are promising drug delivery for topical application as being more useful than conventional formulation therapy.
A Comparison of Efficacy among Syrian diabetic patients treated with Empagliflozin versus Dapagliflozin, a Randomized, Triple-blind, Two-period crossover study
Authors: Kharrat Helu Nihad , Nattouf Abdulhakim
Published: November 2023

Objective: To directly compare the effectiveness of the highest approved doses of two sodium-glucose co-transporter 2 (SGLT2) inhibitors Empagliflozin and Dapagliflozin as part of Dual oral antidiabetic agents in type 2 diabetes (T2DM) patients. Methods: This study was a randomized, triple-blind, crossover, 24-week monocenter Trial. T2D Patients were randomized to receive metformin 1000mg b.i.d with Empagliflozin 25 mg/day and then metformin 1000mg b.i.d with Dapagliflozin 10mg/day (n=24) or vice versa (n=23). Each treatment period was 12 weeks with a 10-day washout period in between (without stopping metformin). The parameters evaluated at baseline and after 12 and 24 weeks. The primary outcome was the mean change from baseline in haemoglobin A1c (HbA1C), Fasting Blood Glucose (FBG), Body Mass Index (BMI), Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP). Analyses were done per the Per-protocol principle. Results: Empagliflozin administration showed significant reductions in HBA1C, FBG, BMI, SBP and DBP (p>0.05), Dapagliflozin administration improved the levels of HBA1C, FBG, BMI, SBP and DBP but it was significant only in FBG (p=0.001) and SBP (p=0.035). There were no significant changes from baseline in HbA1c, FBG, SBP and DBP with Empagliflozin treatment compared with Dapagliflozin (P<0.05). Both groups showed reductions in BMI but the reduction was greater in the Empagliflozin group (between groups; p=0,044). Conclusions: This study showed that SGLT2 inhibitors can be effectively used as dual oral antidiabetic agents in T2D patients who are treated with metformin. More specifically, Empagliflozin was more effective in reducing BMI.
Review on Sensitivity and Selectivity of Colorimetric Sensor Based on Responsive Polymer against Pathogenic Bacteria
Authors: Retno Wikantyasning Erindyah , Hasanah Uswatun
Published: November 2023

Pathogenic bacteria cause severe cases in human health, especially pathology in infectious diseases. The incidence of bacterial resistance to antibiotics also seriously impacts human health, so a detection method that is more sensitive, fast, and easy is needed. Responsive polymers are biocompatible, non-thrombogenic, firm, elastic, flexible, and easy to shape, and have become the choice for colorimetric sensors against bacteria. This narrative review aims to determine the sensitivity and selectivity of responsive polymers as a sensor system against pathogenic bacteria. The compilation of this narrative review was traced through the PubMed database using the keyword "(sensitive polymers OR responsive polymers) AND (colorimetric detection OR colorimetry) AND (bacteria OR pathogen)". The inclusion criteria used were primary literature with the publication year 2010-2020. From these results, nine published articles that met the criteria for review were determined. Based on the analysis results, the responsive polymer has a sensitivity with a LOD range of 1-108 CFU/mL and high selectivity in colorimetric sensors to detect pathogenic bacteria.
Comparative Evaluation of HEP-2(Cincinnati) and Vero cell lines sensitivity to Bivalent Oral Polio Virus Vaccine (Type 1 and Type 3) by using In-vitro Microtitration Potency Assay
Authors: Surekha Surekha , Kumar Anoop , Kasana Harit , Meena Jaipal , Sayal Archana
Published: November 2023

Background: Poliomyelitis is a severe viral infectious disease caused by poliovirus and usually, children under the age of 5 years are affected mostly who are not immunized or fully vaccinated. For precise evaluation of quality control testing of the vaccine is based on three parameters i.e. Identity, efficacy and safety. One of the most important test is potency to know about the efficacy and well-founded results in quality control of vaccines. Objectives: To evaluate the and compare sensitivity of HEP-2(Cincinnati) and Vero cell lines to Bivalent Oral Polio Virus Vaccine (Type 1 and Type 3) Methods: The sensitivity of Hep 2-c and Vero cell lines were compared by using a cell culture-based potency test based on CCID 50 /SHD. Results: Present study showed that the Hep 2-C is most sensitive for bOPV (Type1 and Type3) and the Vero cell line is less sensitive for Type 3 Virus. The Vero cell line is similarly sensitive as Hep 2-c for Type1 virus and TVC (Total Virus Count) of bOPV. Conclusions: The present study, suggest that the Vero cell line can also be used for the Potency assay of TVC (Total Virus Count) and Type1 in bivalent oral polio vaccine or monovalent (Type1) OPV along with Hep 2-c cell line.
A New Analytical Method for Determination and Quantification of Residual Solvents in Relugolix Api Bulk Drug by GC-MS Method
Authors: Ramachandra Rao Immani , Lavanya Chava , Punitha P.
Published: November 2023

Relugolix API residual solvents (2-Propanol, n-Hexane, ethyl acetate, tetrahydrofuran, and toluene) were studied using a concise and low-cost GC-MS method. N-Methyl-2-pyrrolidone diluent is used (NMP). The DB-5 30m, 0.53 mm, 0.25 m film thickness column, 1.5 mL/min of helium as the carrier gas, 44.4 cm/sec of linear velocity, 200° C for the injector, 220° C for the mass detector ion source, 280° C for the interface, and a predetermined oven program were used to achieve the chromatographic separations. Within a 3.0 minute period, five residual solvents were eluted. The method was successfully validated by determining Specificity, Linearity, Accuracy, Limit of Detection, and Limit of Quantification.
Development of opportunities to provide medication treatment for seniors through mobile applications
Authors: Babaskin D. V. , Zakharchenko M. A. , Shestakov M. S. , Litvinova T. M. , Babaskina L. I. , Glazkova I. U.
Published: November 2023

To address the tasks of developing opportunities to provide pharmaceutical therapy to the elderly via mobile applications, as well as to expand and improve the market for applications in this functional group, it is vital to investigate the attitudes of seniors toward obtaining and using drug treatment applications. The study goal is to research the reasons preventing senior citizens in Russia from adopting mobile applications for drug treatment by determining their attitudes to applications in general and with an emphasis on differences between potential and actual consumers in particular. The objects of the study are three groups of mobile applications for drug treatment: healthcare applications (mHealth), applications of pharmacy chains and individual pharmacies, and drug search applications (aggregators of medications and their prices). The subjects of the study (survey participants) are 816 elderly users of mobile applications for drug treatment from 37 constituent entities of the Russian Federation. The respondents are divided into two target segments: actual app users (S1) and potential app users (S2). Field research is conducted using the oral survey (24.5%) and online survey methods (75.5%) with a structured questionnaire. The study identifies and examines 14 formative factors and 13 factors that maintain respondents' attitudes to applications. The key personal motivational incentives (10 parameters) and barriers (10 parameters) to the adoption of mobile applications by the elderly are determined and researched. Personal reasons that prevent seniors from adopting mobile applications are established, such as the need to get multiple apps for drug treatment (in S1 – 74.5% of respondents; in S2 – 81.7%), difficulties in learning to use the app (in S1 – 32.3%; in S2 – 64.4%), and deterioration of vision (in S1 – 57.8%; in S2 – 62.3%). An emphasis is put on the especially prominent personal motivational barriers in the age groups of seniors between 65 and 75 and 75 and older. The obtained results point to the main limitations and conditions of implementation of mobile applications from the point of providing drug treatment in Russia. In addition, the findings reveal the opportunities to improve the provision of drug treatment to the elderly through mobile applications by setting limits on applications and possibly leveling out the reasons that prevent seniors from adopting mobile applications.
DEVELOPMENT OF QUICKNESS AND SPEED POWER IN YOUNG, 11-12 YEARS OLD, ATHLETES SPECIALIZING IN SHORT DISTANCE RUNNING
Authors: Smbatyan V. A. , Simonyan T. G.
Published: November 2023

The aim of the research is to study the effectiveness of the developed method of speed development among young athletes specializing in short-distance running.
The task of the study is:
1. To theoretically justify the problem of speed development in young athletes on short distances.
2. To develop a method of speed development among young athletes at short distances.
3. To evaluate the effectiveness of the developed method according to indicators of speed development in young athletes at the age of 11-12 at short distances.
As a result of the research, the following conclusions can be drawn. Speed and high-speed strength are qualities that manifest themselves in very diverse and specific ways in various physical actions of a person.
The analysis of the scientific and methodological literature showed that at the age of 11-12 a child's body undergoes the most complex restructuring and sports training. In particular, short-distance running can have both a positive and a negative impact on the child's growth and development. Knowing the anatomical, physiological and psychological features of the development of children aged 11-12 years and taking into account the revealed methodological techniques in training activities will contribute not only to the natural course of growth and development of the child's body, but also to the improvement of the quality of the educational and training process in short-distance running classes.
THEORETICAL ANALYSIS OF PROFESSIONAL BURNOUT PROBLEMS
Authors: Hakobyan K․ Z.
Published: November 2023

The aim of the research is to analyze the essence, components and symptoms of the professional burnout problem, documented in the scientific and methodological literature.
The analysis of the scientific literature shows that burnout is a complex phenomenon that affects employees and has a adverse consequences on their well-being and organizational performance. Thus, by studying and classifying theories, we can develop a comprehensive image of burnout which includes personal characteristics, organizational factors, and their complex interactions. This comprehensive understanding is crucial for developing effective strategies and measures to prevent and manage burnout in the workplace.
SOCIAL INTELLIGENCE AS AN INDICATOR OF A COACH’S
PROFESSIONAL COMPETENCE
Authors: Khitaryan D. S. , Stepanyan L. S. , Lalayan G. A.
Published: November 2023

The purpose of the research is to study the role of social intelligence as a professional competency among coaches. In our research, we observed that the ability to predict behavior and situations, which is associated with the number of successful athletes trained, remains relatively stable with an increase in work experience. However, there is a decline in overall verbal comprehension and social intelligence indicators.
Based on these results, it can be concluded that coaches’ professional competence is largely determined by their ability to predict situations and behavior, as well as their understanding of non-verbal signals. Interestingly, an increase in work experience negatively impacts the understanding of verbal signals and the overall social intelligence indicator.
Several key findings emerge based on theoretical analysis and the study conducted with the coaches. Firstly, the coaches show an average level of overall social intelligence, in the first and second subtests, which assess understanding of non-verbal signals and social situation analysis, showing results that are more distinct. The significant positive correlations between these subtests, the general social intelligence indicator and the number of athletes achieving sports success, suggest that coaches with better-developed social intelligence abilities in predicting situations and understanding non-verbal signals have a greater impact on athletes' sport success.
Furthermore, negative or unreliable correlations were found between the length of service of coaches and indicators of social intelligence. This implies that the ability to predict behavior and situations, associated with successful athletes, remains relatively stable over time, while indicators of verbal understanding and overall social intelligence tend to decline with increased length of service.
Therefore, seeing the influence of coaches' social intelligence on athletes' performance and the decline in social intelligence with increasing experience, it is crucial to provide ongoing social intelligence training for coaches. This will help to maintain and enhance their social intelligence skills, ultimately benefiting the athletic performance of their athletes.
PREVALENCE OF RISK FACTORS FOR NON-COMMUNICABLE DISEASES AMONG MASTERS
Authors: Abovyan V. A. , Nalbandyan G. L. , Ascatryan G. R. Ascatryan
Published: November 2023

The purpose of the study is to identify the prevalence of risk factors of chronic non-communicable diseases among Masters of Armenian State Institute of Physical Culture and Sport and to give suggestions on reducing risk factors.
The research was carried out in Armenian State Institute of Physical Culture and Sport using our localized version of "CINDI- (Countrywide Integrated Non Communicable Disease Intervention) health monitoring" questionnaires. A survey was carried out among 83 Masters.
Analysis of risk factors shows that 87.3% of respondents have at least one risk factor, 24% of respondents smoke, 55.4% have consumed alcohol during the month, 19% are overweight, 9% are obese, 19.2% of respondents are inactive . Only 20% of students meet the WHO guidelines for daily consumption of fruits and vegetables.
Risk factors for non-communicable diseases are quite common among masters and 87.3% of them have at least one risk factor. Although the majority of masters have high physical activity, 1/3 of them are obese and overweight.
THE IMPORTANCE OF INTRODUCING SPORTS TOURISM IN PUBLIC SCHOOLS
Authors: Danielyan S. H. , Petrosyan N. K.
Published: November 2023

The aim of the research is to study and evaluate the possibility of implementing sports tourism in public schools.
As a result of our work, we highlighted important points documenting the positive and important significance of mountain tourism in public schools.
1. Every element of sports tourism is aimed at maintaining health and is considered an important promoter of a healthy lifestyle. It has tendencies to form a healthy society.
2. Sports tourism with its various game, extreme and interesting directions can provide schoolchildren’s motivation, children's movement activity, improve interdisciplinary connection.
3. It can be incentive to have a fighting army, especially when taught from an early age.
The work done was successful and as a result of the pilot program in 2023, the topics of the "Mountain Preparation" subject were included in Premilitary Training textbooks published by the Ministry of Education and Culture.
Future programs should focus on children's physical fitness initial and final outcomes, as well as the development of children's analytical and alternative problem-solving skills.
This research will be ongoing and will analyze the impact of sports tourism, specifically Mountain Training, on students' health, physical and psychological fitness.
FEATURES OF PHYSICAL AND TECHNICAL FITNESS OF YOUNG
BASKETBALL PLAYERS
Authors: Davtyan Y.  L. , Muradyan D. G. , Aleksanyan N. Y.
Published: November 2023

The aim of the research is to study technical and physical training of young, 12-14 years old, basketball players. The task is to offer new methods and means to improve the level of physical and technical fitness of young basketball players.
The research was carried out in two stages with basketball players at the age of 12-14 in Yerevan and in different regions of Armenia: the 1st stage September-October 2022,the 2nd stage March-April 2023. It is planned to carry out third and fourth stages in 2023-2024.
As it can be seen from the data obtained from the first and second stages, not all test indicators improved at the second stage: at the first stage, it was 3.4 seconds and at the second stage 3.6 seconds, the results of long jumps in the first stage were 203cm and in the second stage 200cm.
In the process of developing the physical and technical training of young basketball players, it is necessary to use such methods and means that can simultaneously develop physical and technical indicators.
In order to keep the efficiency of game actions throughout the game, it is necessary to use different approaches and means of developing physical and technical qualities in the preparatory and competitive periods, depending on their athletic fitness and age characteristics.
POSITIVE AND NEGATIVE PROBLEMS OF EARLY
SPECIALIZATIONS IN HANDBALL
Authors: Mikaelyan G. J.
Published: November 2023

The aim of the research is to study the aim of early specialization in handball, to disclose the advantages and disadvantages of being specialized in handball from a young age, to study the sportive way of handball players who started playing handball at an early age and come to a conclusion.
The research was carried out among 10 coaches from various districts of the republic, of different gender and age. We also talked with 10 athletes of different gender and age who started their sport activities before they were 9. They filled in the questionnaires including 5 questions.
The overwhelming majority of the interviewed specialists are in favor of early specialization. Both the coaches and athletes mentioned a negative side – age peculiarities which are not taken into consideration.
METHODS OF IMPROVING THE FLEXIBILITY OF TEENAGE FEMALE
ATHLETES IN SAMBO
Authors: Najaryan K. M.
Published: November 2023

The aim of the research was to develop an effective methodology for developing flexibility skills of 10-12-year-old teenage sportswomen.
The data obtained by us convincingly confirm that further improvement of flexibility will help young female athletes to master simple and complex technical elements of sambo in the future. Our research confirms this methodical rule formed in sports practice. Thus, the results of the experiment prove that the methodology developed by us is effective for developing the flexibility of young sportswomen.
The analysis of scientific-methodical literature, pedagogical observations, the analysis of the pedagogical activities of leading public education coaches, as well as the mathematical analysis of the obtained results, allow us to draw some conclusions. Based on the results of the survey of the leading coaches of the republic, it can be concluded that the development of flexibility of teenage sportswomen should start from the initial stage of training. The development of flexibility contributes to increasing the effectiveness of technical-tactical operations. The flexibility exercises should be performed during the pre-workout as well as at the end of the training in the form of stretching exercises, contributing to the recovery of the body of the trainees.
Penerapan Sistem Pakar Dalam Mendiagnosa Penyakit Kerbau (bubalus bubalis) Menggunakan Metode Teorema Bayes
Authors: Simamora Ita Purnamasari , Muhazir Abdullah , Hamdani Rita
Published: November 2023

Kerbau adalah binatang memamah biak yang menjadi ternak bagi bangsa didunia pada dasarnya ternak kerbau digunakan sebagai tenaga kerja, selanjutnya untuk penghasil daging dan juga susu.Penyakit Kembung Perut (Bloat). Dampak dari penyakit tersebut dapat membuat hewan ini cepat mati. Maka dari itu harus ada cara pengobatan dan penanggulangan pada penyakit untuk jenis hewan kerbau  ini, termasuk pula cara pendeteksian awal penyakit hewan ini juga harus cepat. Tujuan hal itu adalah untuk mengurangi dampak buruk yang ditimbulkan oleh penyakit ternak kerbau tersebut sehingga hasil yang diperoleh bisa ditingkatkan. Dengan adanya Sistem Pakar ini, dapat dijadikan layanan konsultasi untuk membantu dalam mengdiagnosis penyakit Kembung perut berdasarkan gejala- gejala klinis yang dialami oleh pasien, sehingga dapat digunakan dalam pengambilan kesimpulan diagnosa awal sebelum melakukan pemeriksaan intensif laboratorium. Adapun tingkat keakurasian dalam mendiagnosis penyakit kembung perut menggunakan metode teorema bayes adalah  76.4 %.
Expert system Untuk Mendiagnosis Penyakit Campak Dan Rubella Menggunakan Metode Teorema Bayes
Authors: Sagala Erialdo Saputra , Setiawan Dedi , Sobirin Sobirin
Published: November 2023

Campak dan Rubella merupakan penyakit yang dapat menular melalui udara yaitu ketika penderita penyakit tersebut bersin atau batuk. Penyakit ini dapat menyerang balita yang berusia 9 bulan hingga 5 tahun sehingga dapat menyebabkan mereka menderita gangguan pendengaran, katarak, keterlambatan berbicara, dan gagal jantung merupakan penyakit yang ditimbulkan oleh virus, Penyakit Campak memiliki gejala demam tinggi, bintik-bintik merah, sakit tenggorokan, batuk kering,pilek, sakit kepala, mata berair dan mata merah. Penyakit ini sangat gawat apabila dengan komplikasi peradangan pada balita, sakit perut, demam dengan kaki tangan dingin dan dapat menyebabkan ke Penyakit Rubella adalah penyakit yang mirip dengan campak, gejalanya berupa demam ringan atau bahkan tanpa gejala sehingga sering tidak terdeteksi. Rubella sangat berbahaya pada wanita hamil terutama pada kehamilan  dapat mengakibatkan keguguran atau bayi lahir dengan cacat bawaan yang disebut sindrom rubella yang menyebahkan pertumbuhan bayi. Banyak orangtua di Medan yang sulit mengetahui gejala–gejala pada bayi ketika terkena campak dan rubella.
Implementasi Sistem Pendukung Keputusan Dalam Perekrutan Karyawan Baru Menggunakan Metode Waspas
Authors: Ziliwu Yaaman , Zunaidi Muhammad , Santoso Ismarwardi
Published: November 2023

Penulisan skripsi ini bertujuan untuk membangun dan merancang Sistem Pendukung Keputusan Perekrutan Karyawan Baru yang dapat membantu pihak  Rumboss Barber Saribu Dolok yang masih melakukan perekrutan karyawan secara manual atau belum terkomputerisasi. Oleh karena itu dibangunlah sebuah Sistem Pendukung Keputusan berbasis web yang menggunakan salah satu metode Sistem Pendukung Keputusan  yaitu Metode WASPAS. Metode Waspas merupakan sebuah metode yang dapat membantu dalam pengambilan keputusan serta memiliki tingkat selektifitas yang baik karena dapat menentukan tujuan dari kriteria yang bertentangan.dimana kriteria dapat berupa keuntungan (benefit) ataupun kriteria biaya (cost). Hasil yang diperoleh dari sistem yang dibangun itu sendiri adalah berupa urutan nilai untuk setiap alternatif yang telah dihitung berdasarkan kriteria yang telah ditentukan sehingga menghasilkan keluaran berupa alternatif yang memiliki nilai dari yang tertinggi hingga yang terendah dalam bentuk perankingan. Dengan demikian diaharapkan dapat membantu pihak Rumboss Barber Saribu Dolok dalam menentukan atau memutuskan calon karyawan mana yang akan direkrut berdasarkan hasil dari Sistem Pendukung Keputusan tersebut
Peningkatan Layanan Pelanggan Dalam Memilih Merek Fashion Menggunakan Metode Moora
Authors: Br Tarigan Eunike Aprianty , Rahmadiansyah Dudi , Wahyuni Meri Sri
Published: November 2023

Merek merupakan suatu identitas dari ciri khas dari suatu produk dan menjadi pembeda dengan produk yang lain meskipun serupa. Merek pada saat ini sangat banyak dan beragam yang membuat konsumen dilema untuk memilih merek yang ditawarkan dipasar salah satunya di bagian rok fashion wanita. Pada suatu Toko Fashion Boutique menyediakan beragam merek yang terkadang design dan modelnya hampir sama. Hal ini yang membuat konsumen membutuhkan waktu yang lama untuk membandingkan merek yang satu dengan merek yang lain. Bahkan konsumen juga mengalami kesalahan dalam memilih merek fashion.  Untuk menyelesaikan permasalahan diatas maka dibuatlah sebuah sistem yang dapat membantu dalam memilih merek rok fashion yang ada berdasarkan dari permintaan kriteria pelanggan  yang kemudian akan diambil keputusan yang terbaik yaitu dengan  Sistem Pendukung Keputusan menggunakan Metode Moora. Metode Moora adalah suatu metode yang memiliki tingkat selektifitas yang tinggi dan mudah dipahami dimana kriteria tersebut dapat bernilai menguntungkan(benefit) atau tidak menguntungkan(cost). Hasil yang diperoleh berdasarkan penerapan metode MOORA pada Sistem Pendukung Keputusan yang telah dibangun yaitu membuat waktu untuk memilih merek rok fashion lebih cepat , mengurangi kesalahan dalam memilih rok fashion dan meningkatkan pendapatan pada toko.
Sistem Pendukung Keputusan Pemilihan Base Location Rencana Terbang Drone Fixed Wings Dengan Metode Waspas
Authors: Pranoto Rizki Teguh , Tugiono Tugiono , Lusiyanti Lusiyanti
Published: November 2023

Pemanfaatan teknologi Unmanned Aerial Vehicle (UAV) sudah mengalami perkembangan yang begitu pesat pada beberapa tahun terakhir. UAV merupakan pesawat tanpa awak yang dikendalikan jarak jauh oleh pengguna di darat melalui sistem komputer atau remote control. Pada dasarnya pemanfaatan drone digolongkan bergantung pada sektor penggunanya. Untuk keperluan sipil, drone digunakan untuk pengumpulan data geospasial seperti, pemetaan daerah, pemetaan lahan pertanian, pemantauan lalu lintas ataupun pemotretan daerah pasca bencana. Penggunaan UAV dilakukan untuk menghemat waktu pemetaan dan sangat direkomendasikan dalam menyelesaikan pekerjaan dalam kurun waktu tertentu. UAV berjenis fixed wings sangat bagus untuk pemetaan lahan pertanian yang luas. Dibeberapa perusahaan fixed wings sudah digunakan oleh orang yang profesional, penggunaan fixed wings harus berhati-hati, termasuk pada penentuan base location. Sebagian kasus yang terjadi pada penggunaan fixed wings ini adalah terjadinya kerusakan yang diakibatkan drone tidak dapat landing pada titik awal take off. Hal ini juga dikarenakan kurangnya perhatian dan antisipasi dari remote pilot dalam menentukan base location untuk take off/landing. Untuk itu dibangunlah sebuah sistem pendukung keputusan yang dirancang guna membantu menyelesaikan masalah dalamn pemilihan base location. Pada sistem ini akan diterapkan metode Weight Aggragated Sum Product Assessment (WASPAS). Hasil dari sistem yang dirancang, dapat membantu pengguna atau remote pilot dalam pemilihan base location pada rencana terbang drone fixed wings dengan baik, dan kemudian terciptalah sistem berbasis desktop yang efisien dan dapat membantu pengguna untuk mengambil suatu keputusan.
Implementasi Data Mining Dalam Mengelompokkan Data penduduk Kurang Mampu Menggunakan Metode K-Means Clustering
Authors: Waruwu Arisman , Yetri Milfa , Setiawan Feri
Published: November 2023

Penduduk kurang mampu merupakan permasalahan bangsa yang sangat mendesak dan sering kali di tandai dengan tingginya tingkat pengangguran dan keterbelakangan. Salah satu aspek penting untuk mendukung langkah – langkah penanggulangan  dalam penanganan penduduk kurang mampu, pemerintah dapat juga melakukan evaluasi kebijakannya terhadap penduduk serta membandingkan data penduduk kurang mampu antar waktu dan daerah serta menentukan targetnya agar dapat bisa menyelesaikan  masalah yang di alami  penduduk. Data mining merupakan istilah dari pattern recognition merupakan metode yang di gunakan untuk pengelolaan data yang akan di gunakan, untuk menemukan pola yang tersembunyi dari pengelolaan data. Algoritma K-Means merupakan salah satu metode yang menggunakan konsep descriptive dan dapat digunakan untuk menerapkan suatu algoritma dalam penentuan suatu objek kedalam cluster tertuntu. Hasil penelitian ini bermanfaat bagi Desa Hiliwaele II dan dapat dikategorikan sebagai suatu proses pengelompokkan record, observasi, atau mengelompokkan data yang memiliki kesamaan objek, dengan klasifikasi tidak ada variabel target dalam melakukan pengelompokan pada proses clustering.
Sistem Pendukung Keputusan Pemilihan Peserta Jamkesmas Di Desa Hutabulu Mejan Kabupaten Toba Menerapkan Metode Waspas
Authors: Widyasari Ayu , Suryanata M. Gilang , Halim Jufri
Published: November 2023

Pada Jaminan Kesehatan Masyarakat berhubungan dengan pendataan terhadap keluarga miskin atau masyarakat yang kurang mampu, untuk mendapatkan bantuan dari pemerintah. Dalam pemilihan peserta jamkesmas masih memiliki beberapa masalah seperti masih adanya subjektivitas yang cenderung penilaian peserta jamkesmas tersebut masih mengarah kepada pendapat pribadi sehingga proses penilaian memakan waktu yang cukup lama karena dilakukan secara manual. Sehingga mengakibatkan proses penilaian keputusan menjadi lambat dan hal ini tentunya tidak baik karena mempengaruhi kelancaraan operational.Untuk mengatasi masalah yang dihadapi kantor kepala desa hutabulu mejan diperlukan sistem pendukung keputusan untuk memilih calon jamkesmas. Saat memilih metode, perlu menggunakan metode Weighted Aggregated Sum Product Assessment (WASPAS). Sistem akan memperoleh keputusan rangking berdasarkan setiap alternatif pilihan sejumlah kriteria yang telah ditetapkan. Untuk mewujudkan sistem pendukung keputusan tersebut, dirancang sebuah program aplikasi sistem pendukung keputusan. Didesain dengan menggunakan aplikasi berbasis visual basic (vb) yang akan digunakan dengan konsep multi-user, yang didesain hanya untuk kenyamanan pengguna, melalui aplikasi sistem pendukung keputusan ini diharapkan dapat mempermudah proses penentuan pemilihan peserta jamkesmas, diharapkan mendapatkan hasil terbaik dari metode Weighted Aggregated Sum Product Assessment (WASPAS).
Implementasi Sistem Pakar Mendiagnosa Penyakit Dompo (Herpes Zoster) Menggunakan Metode Certainty Factor
Authors: Fadila Wafiq , Azmi Zulfian , Al-asy'ari Abu Hasan
Published: November 2023

Herpes zoster merupakan virus yang mengakibatkan varicella dan herpes zoster. Penyakit ini disebut sebagai cacar air karena gelembung atau bisul yang terbentuk pada kulit apabila pecah mengeluarkan air. Penyakit ini sangat mudah untuk menyebar kepada orang lain, terutama pada anak – anak yang belum pernah terkena varicella zoster atau yang dikenal dengan penyakit herpes zoster. Penyebaran virus dapat melalui udara dan kontak langsung pada penderita. Sulitnya mendapatkan informasi mengenai penyakit ini secara cepat dan juga kondisi pada klinik ketika terjadi antrian yang cukup panjang serta apabila dokter sedang tidak berada diklinik  Oleh karena itu, diperlukan sebuah pemecahan masalah dengan memanfaatkan bidang ilmu Sistem Pakar dengan metode komputasi yaitu Certainty Factor. Sistem ini nantina dapa membanu mendiagnosa penyakit herpes zoster demgan cara memberikan solusi dan penanganan kepada penderita herpes zoster Hasil yang diperoleh dari Sistem Pakar menggunakan metode Certainty Factor  yaitu memberikan hasil akhir berupa nilai kemungkinan hasil diagnosa terhadap sebuah penyakit serta solusi terhadap penyakit Dompo (Herpes Zoster)
Penerapan Metode Clustering Dengan Algoritma K-means Pada Pengelompokan Data Calon Siswa Baru
Authors: Norshahlan Muhammad , Jaya Hendra , Kustini Rini
Published: November 2023

Proses Penerimaan Siswa baru di setiap sekolah menghasilkan data siswa yang sangat berlimpah berupa data alamat dan data lainnya. Hal tersebut terjadi secara berulang dikarenakan penerimaan siswa baru di setiap tahunnya. Penelitian ini bertujuan untuk melakukan pengelompokan data siswa sekolah Harapan Bangsa dengan memanfaatkan proses data mining dengan memnggunakan metode clustering. Adapun Algoritma yang digunakan adalah Algoritma K-Means Clustering. Algoritma K-Means merupakan Algoritma pengelompokan iterative yang melakukan partisi set data kedalam sejumlah K cluster yang sudah ditetapkan diawal. Implementasi dengan menggunakan aplikasi berbasis website digunakan untuk membantu menemukan nilai yang akurat. Atribut yang digunakan untuk tahapan clustering adalah jurusan, asal sekolah, dan tahun lahir. Cluster siswa yang terbentuk adalah 2 cluster, yaitu 47 items cluster pertama, 23 items cluster kedua. Adapun tujuan penelitian ini adalah salah satu dasar pengambilan keputusan untuk menentukan strategi dalam mempromosikan sekolah. Dapat disimpulkan bahwa proses clustering mencapai 3 kali iterasi untuk mendapatkan hasil clustering akhir, sehingga dapat disimpulkan bahwa peminat terbanyak di masing -masing jurusan dan asal sekolah, sehingga pihak kampus dapat memikirkan strategi promosi.
Sistem Pendukung Keputusan Dalam Menentukan Pupuk Terbaik Pada Tanaman Padi Menggunakan Metode Preference selection index
Authors: Panjaitan Mario Febrian , Syahputra Trinanda , Hutasuhut Masyuni
Published: November 2023

Desa perkebunan Ramunia Kecamatan Pantai Labu juga sangat mendukung dan memperhatikan para petani padi khususnya yang tergabung dalam kelompok tani, Namun permasalahan yang ditemukan pada Desa perkebunan Ramunia Kecamatan Pantai Labu adalah diantaranya adalah proses pemilihan pupuk terbaik untuk masyarakat yang menaman padi terkadang dilakukan dengan waktu yang lama dan hasil yang kurang akurat, dikarenakan banyaknya varian atau merk dari pupuk yang beredar dipasaran sehingga merasa bingung ataupun ragu untuk memberikan rekomendasi terkait pupuk yang cocok bagi petani. Selain itu, banyaknya varian pupuk juga menimbulkan waktu penilaian yang lama apabila harus diuji dan dilakukan penilaian secara satu persatu. Maka dari itu dibangunlah sebuah Sistem Pendukung Keputusan yang dapat melakukan penilaian terkait rekomendasi pupuk terbaik untuk tanaman padi berdasarkan kriteria yang telah ditetapkan. Sistem ini nantinya akan dikombinasikan dengan metode Preference Selection Index (PSI) sebagai metode komputasi. Metode PSI merupakan metode untuk memecahkan multi kriteria pengambilan keputusan. Dalam metode yang diusulkan itu tidak perlu untuk menetapkan kepentingan relatif antara atribut. PSI merupakan metode untuk memecahkan multi kriteria pengambilan keputusan. Hasil yang diperoleh adalah terciptanya sebuah sistem pendukung keputusan yang dapat memberikan output (keluaran) berupa rekomendasi pupuk terbaik untuk tanaman padi mulai dari nilai yang tertinggi hingga terendah dalam bentuk perangkingan yang dapat membantu petani Desa Perkebunan Ramunia dalam memberikan rekomendasi pupuk terbaik untuk tanaman padi.
Investigation of Vietnamese monazite concentrate decomposition by alkaline (KOH) baking method
Authors: Hoang Xuan Thi , Nguyen Thi Men , Hoang Thi Tuyen , Ngo Van Tuyen , Hoang Nhuan
Published: November 2023

The alkaline (NaOH) hydrometallurgy for monazite concentrate is currently being used in the industrial production of total rare earth oxides (TREOs) and thorium oxide (ThO2). Besides the acknowledged advantages, the hydrometallurgical process also has certain disadvantages such as the requirement for ultra-fine grinding to -325 mesh, and the hydrometallurgy time extended from 8 to 10 hours to achieve ~93 % efficiency. The present paper report a new roasting process using potassium hydroxide (KOH) applied to Vietnamese monazite concentrates. The experimental data were collected using mass analysis, XRD, and ICP-OES analysis. The optimal efficiency of the process is ~95% after roasting time of 0,5 hours, the temperature at 250oC, and KOH:monazite mass ratio = 1:1. Thereby, the alkaline (KOH) roasting process has solved the limitations of the alkaline (NaOH) hydrometallurgy and shows the development potential in deep processing of the monazite concentrate in Vietnam.
Nilai Filosofi Ornamen Lebah Bergantung Sebagai Aspirasi Penciptaan Seni Lukis Kaligrafi Islam
Authors: Sulaiman  , Ardhy Supraba  , Rizal A.M. Sjachrun  , Abdullah Syukur
Published: November 2023

Nilai filosofi ornamen lebah bergantung merupakan sikaf rela berkorban dan tidak mementingkan diri sendiri, salah satu ajaran yang ditetapkan oleh masyarakat kabupaten Kampar, Khususnya didusun pulao belimbing, yang dianjurkan dalam kehidupan sehari-hari untuk saling tolong-menolong. Maka masyarakat Kampar belajar dari alam salah satunya sarang lebah bergantung. Hal ini menjadi ide pengkarya dalam menciptakan karya seni lukis yang berangkat dari nilai filosofi ornamen lebah bergantung sebagai aspirasi pengkarya. Supaya warisan budaya dapat berkembang terus menerus ditengah kehidupan masyarakat malayu kabupaten Kampar, khususnya dusun pulau Belimbing.