bluuebunny/crossref_metadata_2025 huggingface dataset:
IDEAL–compliant implementation of the Dexter® surgical robot in cholecystectomy: a comprehensive framework and clinical outcomes
Authors: Dohmen Jonas , Weber Julia , Arensmeyer Jan , Feodorovici Philipp , Henn Jonas , Schmidt Joachim , Kalff Jörg C. , Matthaei Hanno
Published: December 2024

Objectives

The integration of advanced technologies is transforming surgical practice, particularly through robotic systems. This study presents the early clinical implementation of the Dexter® surgical robot for cholecystectomy and evaluates clinical outcomes using the IDEAL framework.

Methods

Twenty patients underwent elective robotic-assisted cholecystectomy using the Dexter® robot. A thorough implementation process, including rigorous surgeon and nurse training and standardized care protocols, was established. Data on operative metrics, complications, and patient outcomes were analyzed, and patient well-being was assessed via a postoperative phone survey.

Results

Six surgeons and thirty nurses were trained, with surgeons completing a minimum of 20 h of simulation. Preoperative and operative times were significantly reduced through this process. Comparing the first 10 operations to the second, docking time decreased from 11.4 ± 4.1 min to 7.1 ± 2.1 min (p=0.0144) and operative time improved from 130.5 ± 25.7 min to 99.7 ± 21.8 min (p=0.0134). Mean intraoperative blood loss was minimal, averaging 19.5 ± 31.4 mL, and the average length of hospital stay was 3.1 ± 1.4 days. Postoperative pain levels were low, and patient satisfaction was high, as assessed by telephone survey.

Conclusions

Our findings highlight the value of the IDEAL framework in guiding the systematic evaluation and implementation of new surgical technologies such as the Dexter® robot. A structured approach is essential to improve patient outcomes and safety in the coming digital transformation of surgery.
Experiences with techniques and sensors for smartphone positioning
Authors: Retscher Günther , Gikas Vassilis , Gabela Jelena
Published: December 2024

In this paper, current alternative techniques and sensors embedded in smart mobile devices for localization are reviewed. Firstly, the evolution of smartphone development since the first IBM phone in 1992 and the introduction of the term ‘smart-phone’ in 2000 until present is discussed. The main part of the paper deals then with the sensors and positioning techniques where an overview about the topologies and positioning methods and their applicability for smartphone positioning is provided. The most important sensors and techniques are then elaborated and discussed in detail. They include MEMS-based sensors and wireless positioning options. The wireless options include Bluetooth, Wi-Fi and UWB which may be employed together with MEMS-based inertial sensors. Also the use of the smartphone camera and LiDAR is briefly discussed. Moreover, the most applicable sensor fusion approaches including Kalman filtering, particle filter and map matching are also analyzed. In concluding the paper, new ways in using smartphones for science based on different application examples are showcased.
Study on heat and mass transfer mechanism of unsaturated porous media under CW laser irradiation: with and without carrier gas
Authors: Han Shao-Hui , Dong Yuan , Jin Guang-Yong
Published: January 2025

The use of laser irradiation to remove contaminants from soil is an emerging soil remediation technology with broad application prospects. The mechanisms of temperature field variations, moisture transport, evaporation, and condensation under conditions with or without a carrier gas during laser soil remediation are still unclear. This paper utilizes a heat and mass transfer model under continuous wave (CW) laser irradiation, established based on local non-thermal equilibrium, to analyze the variation characteristics of the physical field within the soil, with or without introducing a carrier gas. The results show that CW laser irradiation can rapidly heat the soil to the expected remediation temperature (90 °C–560 °C). However, the gas transport speed induced solely by CW laser irradiation within the soil is very limited (on the order of 0.01 mm/s), making it ineffective at removing vapor from the soil. In contrast, using a carrier gas significantly improves gas flow (on the order of 10 mm/s), enhancing both heat and mass transfer processes and assisting in removing contaminants during laser soil remediation. This study elucidates the coupled heat and moisture transfer process in unsaturated porous media under conditions with and without a carrier gas, providing theoretical support for applying laser soil remediation.
Sialidosis type 1 in a Turkish family: a case report and review of literatures
Authors: Kılıç Mustafa , İcil Suzan , Sezer Abdullah , Kaya-Güneş Öznur , Comoğlu Selim S.
Published: December 2024

Objectives

Sialidosis type 1 is a rare autosomal recessive lysosomal storage disorder caused by pathogenic variants in the NEU1 gene, which encodes the sialic acid-degrading enzyme α-neuraminidase. Sialidosis type 1 is a milder form with a late-onset phenotype, characterized by progressive myoclonic epilepsy and ataxia with cherry-red spots. Sialidosis type 2 is an early-onset and more severe form presenting with dysmorphic features, hepatosplenomegaly and cognitive delay. Clinical diagnosis is usually supported by increased urinary bound sialic acid excretion and confirmed by genetic analysis or demonstration of α-neuraminidase enzyme deficiency in cultured fibroblasts. The aim of this study was to present a case of type 1 sialidosis, review the literature, and investigate genotype–phenotype correlations, symptom frequencies, and race-specific mutations in patients diagnosed with type 1 sialidosis.

Case presentation

We report herein a family of four Turkish siblings affected with sialidosis type 1 associated with a homozygous variant, c.403G>A p. (Asp135Asn), in the NEU1 gene. A systematic literature review on sialidosis type 1 was carried out, by the PubMed database was searched using keywords included sialidosis and/or NEU1 gene. We selected case reports or series that included genetically confirmed type 1 sialidosis from 1996 to 2023. So far, nearly genetically confirmed 80 patients from unrelated 65 families, more than 40 NEU1 disease causing mutations, have been identified in patients with sialidosis type 1. Among the reported mutations, missense variants are the most common, and few nonsense, frameshift, exonic duplications or small deletions have been reported. c.239C>T p. (Pro80Leu) variant in Chinese and Japanese patients, c.649G>A p. (Val217Met) variant in Japanese patients, c.880C>T p. (Arg294Cys) variant in Indian patients, c.629C>T p. (Pro210Leu) variant in Ecuadorian patients, c.982G>A p. (Gly328Ser) variant in Italian patients, and c.403G>A p (Asp135Asn) and c.625del p. (Glu209Serfs*94) variants in Turkish patients were found higher.

Conclusions

Race-specific variants were found with higher percentages in certain populations.
Providence and Prudence in Kant’s Theology and Ethics
Authors: Kerimov Khafiz
Published: December 2024

This article seeks to reevaluate Kant’s treatment of prudence in his ethics, challenging prevalent interpretations that relegate prudence in Kant to mere technique (skill). Scattered across Kant’s texts, there are indications that prudence (practical judgment) fulfills an essential function in Kant’s ethics: by negotiating the contingencies of an uncertain world, prudence adapts the moral imperative to mutable circumstances. However, Kant is convinced that despair is inevitable for humans, when confronted with the inherent uncertainty and indifference of the natural world. The only remedy against this despair for Kant is faith in a providential God: Kant introduces reliance on God’s providence to reconcile human practical reason with chance and nature’s capriciousness. The article thus underscores the inseparable link between human prudence and God’s providence for living a moral life in the Kantian sense.
Oxeiptosis gene expression profiling identified TCN1 as a prognostic factor for breast cancer
Authors: Zhu Yutong , Zhang Lingyu , Zeng Di , Zhou Pan , Hu Jinhui
Published: December 2024

Objectives

Oxeiptosis could suppress the progression of breast cancer (BRCA). We aim to identify the prognostic factor associated with BRCA using oxeiptosis gene expression profiling and investigate its role in BRCA.

Methods

We extracted RNA sequencing data and clinical information on BRCA samples from the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), and the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) databases using an oxeiptosis-related gene set. Prognosis-related genes for BRCA were screened from the TCGA dataset using bioinformatics analysis. Subsequently, we constructed a prognostic model for BRCA depending on the expression of this predictive factor and analyzed the associated function. The effects of Transcobalamin 1 (TCN1) on BRCA cell function and H2O2-induced oxeiptosis were validated in vitro.

Results

TCN1 was identified as the most strongly associated factor with BRCA prognosis among the differentially expressed genes in oxeiptosis. Patients with high TCN1 expression demonstrated a better prognosis in BRCA. In BRCA, TCN1 was enriched in response to the oxidative stress pathway. Additionally, TCN1 was associated with the expression of immune checkpoints and gene variations. Compared to normal human breast epithelial cells, TCN1 was downregulated in BRCA cells. Overexpression of TCN1 inhibited the proliferation, migration, and invasion of BRCA cells, and enhanced H2O2-induced oxeiptosis in BRCA cells.

Conclusions

Based on the oxeiptosis gene set, we identified TCN1 as a prognostic factor associated with BRCA. The findings highlight the potential of TCN1 as a therapeutic target and provide valuable insights into the development of personalized treatment strategies for BRCA.
Utilizing slip conditions on transport phenomena of heat energy with dust and tiny nanoparticles over a wedge
Authors: Nazir Umar , Khan Umair , Almujibah Hamad , Gündoğdu Hami
Published: January 2025

The present problem investigates 3D flow over an expanding wedge geometry of a tangent-hyperbolic Casson fluid. A two-phase approach considers a liquid phase and a dusty fluid, while a Darcy–Forchheimer law is used to model this fluid flow to capture motion and heat transfer. The several aspects are based on variable thermal radiation, heat sink effects, and slip conditions applied. A tri-hybrid nanofluid comprising silicon dioxide, copper, and aluminum oxide nanoparticles suspended in ethylene glycol, the base fluid, is incorporated into the analysis. The derivation of nonlinear ordinary differential equations (ODEs) is used to characterize momentum, thermal behavior, and fluid motion under these circumstances. ODEs are formulated using similarity transformations and slip conditions. The finite element approach is employed. It is estimated that the fluid phase on the heat transfer rate and skin friction coefficient is higher than the dusty phase on the Nusselt number and skin friction coefficient. The heat transfer rate for ternary hybrid nanofluid is larger than that for hybrid nanofluid.
Certifications and testing methods for biodegradable plastics
Authors: Lee WooSeok , Kim JaeHyeon , Lee Tai Gyu
Published: December 2024

This paper offers a comprehensive review of previous studies and articles on international standards and certification criteria for biodegradable plastics. It highlights key insights into the biodegradation environment and certification processes for these materials. As various countries and organizations intensify research efforts on biodegradable plastics, certification standards for biodegradability are evolving and expanding. This trend is expected to play a pivotal role in shaping international standards. Nonetheless, several challenges persist, including the absence of universally recognized testing methods, inconsistencies between real-world and laboratory biodegradation conditions, and a lack of clear definitions and standardized criteria. Above all, establishing international standards is critical to advancing biodegradable plastics as a viable alternative to conventional plastics.
Design optimization of a fluidic thrust vectoring system based on coanda effect using meta-models
Authors: Kara Emre , Kurtuluş Dilek Funda
Published: December 2024

In this study, parametric optimization is employed to identify optimal output parameters for physical components of HOMER nozzle type fluidic thrust vectoring (FTV) system. Optimization study is conducted on seven output parameters: moment around upper Coanda surface, MA; performance parameter, PP; thrust vectoring angle, θ
T; total thrust, T; thrust vectoring efficiency, η; axial thrust, Tx; transverse thrust, Ty. 440 case studies in design-of-experiment stage are employed, utilizing a range of meta-models. Genetic-Aggregation meta-model exhibited highest coefficient of determination (R2) among tested meta-models. In response surface optimization stage, six objectives are enforced through use of Multi-Objective-Genetic-Algorithm technique. Subsequently, three optimization candidate points are identified for filtering of output parameters deemed to be of particular importance. Among them, candidate point with geometry-4 and parameter-1 = 39.23 m/s, exhibited the highest values for PP, θ
T, η, and Ty, with 4.78 %, 4.48 %, 7.97 %, and 7.94 % higher values, respectively, compared to the baseline geometry.
Reflexiones metodológicas y teóricas sobre el análisis de marcadores pragmáticos: ilustraciones a través del estudio de «es que»
Authors: Enghels Renata , Jansegers Marlies , Van Den Driessche Nele
Published: December 2024

Aunque los marcadores pragmáticos fueron considerados una categoría lingüística marginal hasta finales de los años 80, su estudio ha ganado considerable atención en las últimas décadas. No obstante, el análisis de sus funciones pragmáticas conlleva múltiples desafíos. Estos incluyen la elección entre enfatizar macro o microcategorías funcionales, decidir entre un enfoque semasiológico u onomasiológico, abordar su polifuncionalidad en contextos específicos y establecer criterios formales para identificar funciones pragmáticas concretas. Este trabajo tiene como objetivo principal explorar estas opciones teóricas y metodológicas. Se ejemplifica mediante un estudio de caso del marcador es que, tal y como se observa en el habla coloquial de Madrid. Utilizando una muestra representativa del corpus CORMA (Corpus Oral de Madrid), se argumenta que es que actúa como un marcador pragmático polifuncional con significado procedimental, cuya interpretación es moldeada por el contexto, y cuyo análisis requiere un enfoque multidimensional.
La transcripción de los elementos prosódicos en corpus de habla coloquial espontánea
Authors: Hidalgo Navarro Antonio , Castelló Vercher Carlos
Published: December 2024

La lingüística de corpus tiene como objetivo la generación de bases de datos procedentes de la lengua real dispuestos para su análisis. En este artículo sintetizamos los conceptos básicos sobre transcripción y elaboración de corpus textuales y orales, centrándonos en estos últimos, así como en los sistemas de transcripción de los elementos prosódicos en la conversación coloquial. Tras esta revisión, proponemos un sistema de transcripción prosódica a partir del modelo del Grupo Val.Es.Co. con una serie de criterios e instrucciones objetivas, posibles gracias al empleo de los programas informáticos ELAN y Praat. El sistema propuesto se centra en la identificación y descripción de límites y contornos prosódicos tras el análisis de los fenómenos pausa o alargamiento y reajuste tonal, inflexión final, tonema o F0 inicial y final, enmarcados en las cualidades del sonido duración y F0, respectivamente.
Los corpus orales en la investigación pragmática: el caso de la locución «un poco»
Authors: Méndez Guerrero Beatriz
Published: December 2024

La investigación lingüística basada en corpus ofrece datos empíricos esenciales para identificar patrones recurrentes y llegar a interpretaciones certeras en los estudios pragmáticos. En este artículo, se evidencia la utilidad de tres corpus orales (PRESEEA-Palma, Val.Es.Co. y COJEM) en el estudio de la locución un poco en español. Para realizar la investigación, se ha partido de la metodología cualitativa y cuantitativa, la cual ha permitido examinar los usos, valores y frecuencias de la expresión, así como explorar sus variantes morfológicas. Los resultados del estudio sugieren que se puede establecer una distinción entre usos semánticos con carácter cuantificador de la locución y usos pragmáticos con valores como atenuador, intensificador, aproximativo y reformulador (Vigara Tauste 1992; Fuentes y Alcaide 2002; Matte Bon 1995; Briz 2005; NGLE 2009; Mariottini 2012; Repede 2023, 2024). Asimismo, indican que el género discursivo y las variables sociales de los hablantes inciden parcialmente en el uso que se hace de la locución. Las conclusiones del trabajo llevan a pensar que los corpus aportan información crucial para la investigación comunicativa y que constituyen una herramienta fundamental para los investigadores.
«Un poco» como recurso pragmático-discursivo en corpus orales de nativos y de aprendientes de español: un estudio comparado
Authors: Blanco Domínguez Marta , Conde Noguerol María Eugenia
Published: December 2024

Esta contribución se enmarca en la explotación de corpus aplicada a la enseñanza de lenguas. Concretamente, su objetivo reside en investigar el empleo que en la lengua oral hacen los aprendientes de español L2/LE respecto al que realizan los hablantes nativos del cuantificador un poco como recurso pragmático-discursivo. El corpus ESLORA de español oral (https://eslora.usc.es/) y el corpus Spanish Learner Language Oral Corpora (SPLLOC) (http://www.splloc.soton.ac.uk/index.html) constituyen las fuentes para el análisis empírico. El análisis comparativo de los datos arrojados por los corpus manejados permitirá comprobar las similitudes y diferencias en el uso que de esta partícula hacen los hablantes nativos y no nativos, de las que se podrán extraer algunas consideraciones sobre el tratamiento didáctico del componente pragmalingüístico en el aula de español como segunda lengua o lengua extranjera.
Descripción y análisis de un corpus de español oral de la comunidad de habla LGTBI
Authors: Navarro-Carrascosa Carles
Published: December 2024

Los corpus orales son herramientas esenciales para la investigación lingüística, ya que proporcionan datos auténticos del uso del lenguaje en contextos reales. En este trabajo se presenta el Corpus Oral de la Comunidad de Habla LGTBI (Navarro-Carrascosa 2023a), que recopila muestras de habla de esta comunidad, facilitando el estudio de sus códigos lingüísticos y prácticas comunicativas. Para mejorar este corpus se propone incluir muestras de habla de miembros del colectivo que no fueron acopiadas en los primeros registros, así como ampliar las muestras a más ciudades y áreas rurales, además de las variantes hispanohablantes de otros países para enriquecer el corpus con una mayor diversidad lingüística y cultural. Estas mejoras permitirán que el corpus beneficie investigaciones detalladas sobre variaciones lingüísticas, influencias socioculturales y la evolución del lenguaje en la comunidad LGTBI. Con una expansión y desarrollo continuos, el corpus seguirá proporcionando datos valiosos para una comprensión más completa y diversa del lenguaje dentro de esta comunidad.
El lenguaje juvenil en la ficción traducida: una comparación basada en corpus de una selección de marcadores pragmáticos en catalán y español
Authors: Raya Palmer Adriana
Published: December 2024

El objetivo de este estudio es explorar el habla juvenil ficticia en novelas traducidas, en comparación con el habla juvenil real en la conversación oral. En concreto, el análisis se centra en una selección de marcadores pragmáticos, uno de los muchos rasgos de la oralidad presentes en los diálogos de la ficción. Estos marcadores, que funcionan como elementos expresivos y de manejo de los turnos de habla, son particularmente frecuentes en el habla juvenil. El presente estudio analiza la frecuencia y distribución de los marcadores pragmáticos en dos lenguas, el catalán y el español, mediante un corpus paralelo de diálogos traducidos de novelas contemporáneas y dos corpus orales. Los resultados indican que, acorde con las descripciones previas de la oralidad ficticia, los marcadores pragmáticos son menos frecuentes en el habla juvenil ficticia que en las conversaciones reales. Sin embargo, ciertas excepciones destacan las particularidades del lenguaje traducido y las tradiciones literarias del catalán y el español.
Sobre la obra creadora del Galdós republicano (1907-1918): a la luz de su tiempo y del actual
Authors: Fuentes Víctor
Published: December 2024

Las últimas obras de Benito Pérez Galdós nos ponen ante un autor que continúa buscando métodos y formas nuevas de dar cuenta de la realidad española que le rodea. Lejos de estancarse en el realismo tradicional donde le colocaba la crítica, el autor indaga en nuevas formas expresivas que afectarán tanto a sus novelas como a su teatro. En el siguiente artículo se analizan estos rasgos y se actualiza la postura de Galdós en relación con muchos de los problemas de la España actual que ya en dichas obras se anunciaba y denunciaba.
La actualización del organicismo en Perito en lunas
Authors: Navidad Mario
Published: December 2024

El objeto principal de este trabajo es tratar de analizar el inconsciente ideológico de Miguel Hernández en la escritura de Perito en lunas. Se llamará la atención sobre la manera en que para el poeta los objetos no son sino una representación de Dios en la Tierra; representación mediante la cual se propone una vuelta a la visión barroca del mundo. La interpretación que este artículo propone es que nos encontramos ante una actualización de lo que en las próximas páginas vamos a denominar organicismo. Para ello, se realizará una explicación de la matriz ideológica mencionada y cómo se desarrolla su actualización en el S. XX a propósito del fascismo, se realizará un análisis de textos teóricos de Miguel Hernández y Ramón Sijé, así como de composiciones de Perito en lunas.
“Esta guerra no es nuestra guerra”: Explorando las hipótesis del origen del conflicto Dinka-Nuer en Sudán del Sur
Authors: Caballero Durán Mario
Published: December 2024

El presente trabajo aborda la problemática del origen del conflicto entre los grupos Dinka y Nuer en Sudán del Sur. Para ello, hemos utilizado la revisión bibliográfica como metodología principal. Posteriormente, analizamos brevemente el contexto histórico: el periodo colonial británico; la independencia de Sudán en 1956 y sus guerras civiles; por último, la independencia de Sudán del Sur y su guerra civil desde 2011 hasta la actualidad. Luego, hemos reflexionado acerca de las hipótesis más significativas, a nuestro parecer, que pueden explicar o intuir el origen de este conflicto: la hipótesis ecológica, la hipótesis de la estructura social y la hipótesis de las identidades instrumentalizadas. Finalmente hemos concluido que, si bien estas tres hipótesis puedan ilustrar el origen del conflicto, creemos que es necesario seguir investigando este origen.
Raza y clase social en Hecho en Saturno de Rita Indiana
Authors: Licoa Campos Adolfo Fabricio Licoa Campos
Published: December 2024

Mediante el uso de los conceptos de blanqueamiento, colorismo y antinegritud como herramientas analíticas, este artículo examina la novela Hecho en Saturno (2018) de la escritora dominicana Rita Indiana Hernández, para mostrar la realidad del racismo heredado desde los tiempos coloniales que rige la dinámica social de las comunidades hispano-caribeñas. En su trabajo como escritora, Rita Indiana es consciente de las realidades de su país y del Caribe en general, las cuales reproduce en obras que exponen la desigualdad social, el racismo, las diferencias de clase, la corrupción y la marginación de homosexuales y transgéneros, como sucede en Hecho en Saturno, un texto que expone cómo la discriminación, segregación, inferiorización y marginación histórica de los afrodominicanos empuja a un hombre negro, nacido pobre en un ingenio, a recurrir a estrategias de blanqueamiento para poder ascender en la escala social y mejorar sus condiciones de vida y las de sus familiares.
Vitamin D Supplementation and Colorectal Cancer Patients Outcomes
Authors: Mulyadi Noeray Pratiwi , Rudiman Reno , Purnama Andriana
Published: January 2025

Colorectal cancer is the third most encountered malignancy worldwide in 2018. Some earlier studies indicate a significant influence of vitamin D supplementation on the 5-year survival rate and the rate of metastasis progression in colorectal cancer patients. Studies investigating the effects of vitamin D supplementation on the outcomes of colorectal cancer patients are limited in Indonesia. Therefore, a double-blinded Randomized Controlled Trial (RCT) of the effect of vitamin D supplementation on the outcome of colorectal cancer patients was conducted from April 2022 to March 2023 at the digestive surgery outpatient clinic of Dr. Hasan Sadikin General Hospital Bandung, Indonesia. In this study, 36 patients received vitamin D and 34 patients received a placebo. Data analysis performed using the multivariate analysis with multiple regression revealed no significant relationship between vitamin D supplementation and colorectal cancer patient outcomes. Furthermore, ANOVA analysis indicated no relationship between the analyzed independent and dependent variables in this study.  No relationship was found between vitamin D supplementation and the outcomes of metastasis, mortality, and Karnofsky scores in colorectal cancer patients. Further research with a larger population is still needed to determine the benefits of vitamin D supplementation on the outcomes of colorectal cancer patients.
High spin structure in 140Sm
Authors:   Department of Physics, Maitreyi College, University of Delhi, Delhi, India, Rohila B. , Kaur N. ,   S. A. Jain College, Ambala City, Haryana, India
Published: December 2024

High spin states of 140Sm have been populated using the 116Cd (28Si, 4n) 140Sm heavy ion fusion evaporation reaction. The previously reported level scheme has been considerably modified and extended. Spin and parity assignments have been made using the DCO and IPDCO methods. Multi-quasiparticle configurations have been assigned to various ΔI = 1 and ΔI = 2 bands based on systematic. A band structure similar to 140Sm has been found in 136Ce. So, the alignments in both the nuclei are compared for various band structures having similar band head spin. This helps in assigning the configuration to various band structures. Level structures have been discussed in the framework of the tilted axis cranking model. Lifetimes of states have been measured using the DSAM method.
Mean arrival time distributions of extensive air showers at ultrahigh energies
Authors:   Mustansiriyah University, College of Science, Department of Physics, Baghdad, Iraq, Hussein I.F. , Al-Rubaiee A.A. , Mkhaiber A.F. ,   University of Baghdad, Department of Physics, College of Education for Pure Sciences, Baghdad, Iraq
Published: December 2024

This paper investigates extensive air showers by estimating the muon and electron mean arrival time distributions at ultrahigh energies for various cosmic-ray particles. The Monte Carlo package AIRES (version 19.04.00) was used to perform simulations at energies of 1019 and 1020 eV. The influence of primary particles (p, 56Fe, and 16O), energies, and zenith angles (0°, 10°, and 20°) on the mean arrival time of muonic and electromagnetic shower disks created in an extensive air shower was examined. Parameterized mean arrival time distributions were calculated for secondary particles e-, e+, and μ, created by proton, iron, and oxygen nuclei at energy 1019 eV in a vertical shower. A polynomial function for these primaries in vertical showers was established using the results of this simulation. The results were compared with the KASCADE-Grande experiment and Sciutto's simulations at energy 1020 eV and θ = 0. In this work the construction of a database that can be used to compute the arrival time of elementary particles is crucial in ultra-high energy ranges through an analytic description between the time structure and the distance distribution.
On the influence of metal impurities on the electrical conductivity of the dense plasma of pulse electric discharges in water
Authors:   National Academy of Sciences of Ukraine, Kyiv, Ukraine, Hladkovskyi V.V. , Panchenko V.G. , Porytskyi P.V. , Fedorovich O.A. , Voitenko L.M. , Sviata L.M. ,   Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Published: December 2024

The effect of metal impurities on the electrical conductivity of a dense plasma of discharges in water is considered. Conductivity calculations were based on the method of Grad's moments. It is shown that a small amount of metal impurities can significantly change the value of the electrical conductivity coefficient compared to the case of pure water vapor. It was found that metal impurities can cause both an increase and a decrease in the electrical conductivity of the plasma, which is associated with the processes of interparticle collisions and the presence of clusters.
Model Persediaan yang Mengalami Kemerosotan Berdistribusi Weibull
Authors: Lestari Anisha Ayu , Affandi Pardi , Farid Fuad Muhajirin
Published: January 2025

Penelitian ini mengembangkan model persediaan yang unik dengan mempertimbangkan kemerosotan barang yang mengikuti distribusi Weibull. Model ini dirancang untuk mengatasi tantangan dalam manajemen persediaan, khususnya dalam menghitung biaya total dan optimal. Metode yang digunakan meliputi analisis turunan parsial kedua untuk menemukan biaya optimal dan analisis kemonotonan pada turunan pertama untuk analisis sensitivitas. Hasil penelitian ini memberikan wawasan baru dalam pengelolaan persediaan, dengan model yang efektif untuk memprediksi kemerosotan barang dan mengoptimalkan biaya. Penelitian ini juga menawarkan analisis sensitivitas yang mendalam terhadap perubahan parameter, memberikan panduan penting untuk pengambilan keputusan strategis dalam manajemen persediaan
MATHEMATICAL MODEL OF METAL CORROSION RATE WITH ENVIRONMENTAL FACTORS THAT SPEED UP CORROSION
Authors: Maghfiroh Rofila El , Dewi Mutia Lina , Khusniah Rif'atul
Published: January 2025

Corrosion process often occurs in different types of metals, due to the natural properties of metals. Environmental factors also affect the metals corrosion process, so a mathematical model of metal corrosion rate has been formed with environmental factors accelerating the corrosion process. The mathematical model influenced by initial metal molarity (L), transition metal molarity (N), corrosion product molarity (K), and environmental molarity (X). The mathematical model is a system of diffrential equations whose equilibrium point is then determined. The equilibrium point of the mathematical model of metal corrosion rate with environmental factors that accelerate the corrosion process is stable. Environmental factors that accelerate the corrosion process influence the corrosion product molarity. Corrosion products molarity will reach steady state more quickly if the metal is in an environment that accelerates the corrosion process
PENGARUH JUMLAH HARI HUJAN, SUHU DAN KELEMBAPAN TERHADAP PENYAKIT DEMAM BERDARAH DENGUE MENGGUNAKAN REGRESI LOGISTIK MULTINOMIAL
Authors: Alkatiri Gina , Affandi Pardi , Idris Mochammad
Published: January 2025

Gigitan nyamuk Aedes Aegypti merupakan vektor penyebaran virus dengue penyebab demam berdarah dengue (DBD) ke manusia. DBD biasanya menyerang negara-negara seperti Indonesia yang memiliki iklim tropis atau subtropis. Kasus DBD menyebar di 34 Provinsi Indonesia, dan Kalimantan Selatan menempati peringkat ke-9 berdasarkan Incidence Rate (IR) pada tahun 2018. Kota Banjarbaru menempati peringkat kedua dari 13 Kabupaten/ Kota di Kalimantan Selatan. Selama tahun 2017 hingga 2021, jumlah kasus DBD di Kota Banjarbaru mencapai lebih dari 1000 kasus, melebihi jumlah kasus di Kabupaten/ Kota lain yang terdapat di Provinsi Kalimantan Selatan. Dengan menggunakan model regresi logistik multinomial, penelitian ini mencoba mengetahui pengaruh suhu, kelembapan, dan jumlah hari hujan terhadap penyakit demam berdarah di Kota Banjarbaru. Regresi dengan variabel terikat kategorikal dikenal sebagai regresi logistik multinomial. Metodologi penelitian yang digunakan adalah studi literatur dan uji data kasus jumlah penderita penyakit DBD yang dibagi menjadi tiga kategori yaitu tidak ada kasus, kasus rendah dan kasus tinggi dengan variabel bebas yaitu jumlah hari hujan, suhu dan kelembapan. Hasil dari penelitian menunjukkan faktor jumlah hari hujan berpengaruh signifikan dan positif terhadap penyakit DBD pada fungsi logit kasus rendah, sedangkan faktor suhu dan kelembapan tidak berpengaruh signifikan. Nilai Odds Ratio faktor jumlah hari hujan yaitu sebesar 37,2% berpeluang terjadi kasus rendah untuk setiap peningkatan satu hari hujan dibandingkan tidak ada kasus.
PENGGUNAAN PARTICLE SWARM OPTIMIZATION PADA JARINGAN SYARAF TIRUAN UNTUK KLASIFIKASI SINYAL RADAR
Authors: Jamhuri Mohammad , Utomo Tri
Published: January 2025

Klasifikasi sinyal radar merupakan salah satu tugas penting yang memiliki aplikasi luas, termasuk dalam domain militer, navigasi, dan pengawasan cuaca. Jaringan Syaraf Tiruan (JST) telah terbukti efektif dalam menyelesaikan tugas klasifikasi kompleks berkat kemampuannya dalam memodelkan pola dan hubungan non-linear dalam data. Salah satu tantangan mendasar dalam implementasi JST adalah penentuan jumlah node optimal pada hidden layer, yang secara signifikan memengaruhi performa model. Penelitian ini mengusulkan pendekatan berbasis Particle Swarm Optimization (PSO) untuk mengoptimalkan konfigurasi JST dalam klasifikasi sinyal radar. PSO, sebagai algoritma optimasi berbasis populasi yang terinspirasi dari perilaku sosial kawanan, memungkinkan eksplorasi ruang solusi secara lebih efisien dan efektif dibandingkan metode tradisional. Hasil penelitian menunjukkan bahwa penerapan PSO pada JST secara signifikan meningkatkan metrik performa model, termasuk accuracy, precision, recall, dan F1-score, dibandingkan dengan metode baseline. Namun demikian, penggunaan PSO tidak memberikan peningkatan efisiensi dalam hal waktu komputasi. Temuan ini memberikan kontribusi penting dalam pengembangan model pembelajaran mesin yang lebih akurat untuk aplikasi praktis seperti pengawasan cuaca dan sistem pertahanan, sekaligus memperkaya kajian teoretis di bidang optimasi dan jaringan syaraf tiruan.
Physical activity as a component of a healthy lifestyle of Ukrainian adolescents aged 11-14
Authors:   T.H. Shevchenko National University «Chernihiv Colehium», Ukraine, Hryshchenko S.V. , Kurtova H.Yu. ,   T.H. Shevchenko National University «Chernihiv Colehium», Ukraine, Bashtovenko O.A. ,   Izmail State University of Humanities, Ukraine, Tolchieva H.V. ,   Luhansk Taras Shevchenko National University, Poltava, Ukraine, Kvak O.V. ,   Poltava V.G. Korolenko National Pedagogical University, Ukraine
Published: December 2024

In the modern period in Ukraine, there is a trend of deterioration in the health of adolescent children aged 11-14 years. In this age period, the basic values of forming a healthy lifestyle are laid. It is necessary to form basic social attitudes about a healthy lifestyle among teenagers. The development of motor skills is closely related to health and actively affects the life of children. A healthy lifestyle is based on the readiness and motivation of teenagers for physical self-improvement. Health conservation is an effective form of both preserving and strengthening the health of Ukrainian teenagers aged 11-14 in the conditions of martial law in Ukraine.
The aim of the research is to carry out a systematic analysis of scientific sources in which various aspects of the motor activity of Ukrainian adolescents aged 11-14 years are investigated as a component of a healthy lifestyle.
Motor activity involves a system of active motor actions of teenagers, aimed at creating and forming vital motor skills and skills that determine the preservation and strengthening of health. Solving the problem of motor activity as a component of a healthy lifestyle of Ukrainian teenagers aged 11-14 years by means of physical education and development of motor actions is possible by searching for the latest effective methods.
In order to achieve a high level of motor activity of teenage children, pediatricians, physical education teachers, social specialists, parents of teenagers need to have knowledge in the field of medicine, biology, psychology, pedagogy and methods of physical education, organization and conducting of mass health and sports events. And for teenagers, it is necessary to have practical skills and abilities, as well as the methodology and technique of physical exercises.
The authors declare no conflict of interest.
The role of sensitization to aeroallergens and its determination in children with asthma in Ukraine
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Mozyrska O.V. , Socolova Ya.V. ,   Kyiv City Children's Clinical Hospital No. 2, Ukraine
Published: December 2024

Asthma is a very common respiratory disease in the world. In particular, asthma has a great impact on the health of children. In this study, the distribution of sensitization among children with asthma has been analyzed.
The aim of this study was to investigate the distribution of sensitization among children with asthma in the Ukrainian population.
Materials and methods. The study involved patients (n=98) with asthma aged from 12 to 18 years (median 6 (3;10)). During the examination, children underwent skin prick testing for common aeroallergens. A positive skin prick test was defined as a blister ≥3 mm in diameter after 15 minutes.
Results. Among 98 patients, skin testing with aeroallergens showed a positive result in 76 (77.6%) people: 18 (18.4%) had positive skin testing for at least one allergen, and 58 (59.2%) had polysensitization. Among those sensitized children, 54 (55.1%) were sensitive to pollen allergens, 29 (29.6%) patients were sensitive to cats, 32 (32.6%) to dogs, 30 (30.6%) to Dermatophagoides pteronyssinus, 27 (27.6%) to Dermatophagoides farinae, and 10 (10.2%) to Alternaria.
Conclusion. The most important inhalant allergens for patients with bronchial asthma are pollens (trees, grasses, and weeds), house dust mites, molds, and animal dander. Identifying causative allergens allows for monitoring allergy triggers and determining which asthma patients will be candidates for allergen-specific immunotherapy (ASIT). Today, most children with asthma do not receive ASIT because of the lack of awareness at the primary care level, a lack of testing for aeroallergen sensitization, and financial inaccessibility of examination and treatment in Ukraine.
The study was carried out in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Local Ethical Committee of these institutions. The informed consent of the children's parents was obtained for the research.
No conflict of interests was declared by the authors.
Regional characteristics of the incidence of congenital anomalies, deformities, and chromosomal disorders in newborns in Ukraine
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Turova L.O. , Vezhnovets T.A. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: December 2024

Aim - to determine the regional characteristics of the incidence of the nosological group “Congenital Anomalies, Deformities, and Chromosomal Disorders” (Q00-Q99), considering the availability of genetic doctors and the pregnancy examination rate in Ukraine.
Materials and methods. Statistical data from were analyzed for the period 2012-2021. Incidence rates per 1,000 newborns for the nosological group “Congenital Anomalies, Deformities, and Chromosomal Disorders” (Q00-Q99) were calculated, along with the availability of genetic doctors per 1 million population and the examination rate per 100 pregnant women. Linear regression models were used for mathematical modeling, and model quality was evaluated using the coefficient of determination (R²). Correlation analysis was conducted among the indicators.
Results. Ukraine experienced a significant increase in the incidence of the group “Congenital Anomalies, Deformities, and Chromosomal Disorders” (Q00-Q99) from 2012 to 2021 (from 22.64‰ to 28.49‰), with a projected increase to 33.91‰ by 2026. Regional incidence variation ranged from 47.4‰ in the Volyn to 11.75‰ in the Kirovohrad Oblast. There is a decrease in the number of examined pregnant women per 100 pregnant women from 2012 to 2022 by -8.62%, from 39.84 per 100 pregnant women in 2012 to 36.41% in 2021.
Conclusions. The formed rating distribution of regions by morbidity indicators, provision of geneticists, the indicator of pregnant women examined in the medical genetic service and the growth rate of the indicated indicators from 2012 to 2021 indicates the best result in Poltava, Kirovohrad, Cherkasy Oblast and the existence of significant problems in the organization of medical genetic counseling in Zakarpattia, Lviv and Volyn Oblast.
No conflict of interests was declared by the authors.
Profile of sensitization to fish and seafood allergens in children with allergic conditions in different regions of Ukraine
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Marushko Yu.V. , Moskovenko O.D. ,   Bogomolets National Medical University, Kyiv, Ukraine, Chmil A.I. ,   Bogomolets National Medical University, Kyiv, Ukraine,, Halushko B.L. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: December 2024

The significant increase in allergic reactions to fish and seafood among children in recent years is unabated worldwide. About 40% of children with a food allergy (HA) to seafood are at risk of systemic reactions.
Aim - to determine the prevalence and profile of sensitization to fish and seafood in children in Ukraine; to analyze its age and regional features.
Materials and methods. 3,513 children aged 1 to 18 years with various allergic diseases were examined using molecular component immunoenzymatic analysis of venous blood with the ALEX2 test system (Macro Array Diagnostics GmbH, Austria). The prevalence and structure of sensitization to fish and seafood allergens in children was established, depending on age and region of residence.
Results. Among the examined, sensitization to fish and seafood was detected in 529 (15.1%) children, of which 15 (2.8%) were 1-2 years old, 123 (23.3%) were 3-5 years old, in 173 (32.7%) - aged 6-8 years, in 111 (20.9%) - aged 9-11 years old; in 67 (12.7%) - aged 12-14 years; 40 (7.6%) are 15-17 years old. More often, sensitization to fish and seafood was observed in children from the southern (55 (21.2%) children) and central regions of Ukraine (102 (19.8%) children). Sensitization to fish prevailed - (in 433 (81.9%) children), to seafood - in 96 (18.1%), simultaneously to fish and seafood - in 58 (11%) children. Most children were sensitized to β-parvalbumin: carp - in 291 (55.0%) children, cod - in 206 (38.9%), salmon - in 239 (45.2%), mackerel - in 45 (8, 5%). Sensitization to lobsters was detected in 79 (14.9%) children, crabs in 76 (14.4%), oysters in 73 (13.8%), shrimps in 65 (12.3%) children.
Conclusions. The problem of allergy to fish and seafood in children is urgent. Prevalence of sensitization to fish, mainly to β-parvalbumins of salmon, mackerel and tuna, was revealed. Among seafood, sensitization to lobsters, crabs, oysters and tiger prawns prevailed (in 14.9-12.3% of children). Allergy to fish and seafood was more common in children from the central and southern regions of the country (19.8-21.2% of children).
The studies were carried out in accordance with the principles of the Declaration of Helsinki. The protocol was approved by the Local Ethics Committee of the institution indicated in the work. Information consent from parents and children is obtained for conducting research.
No conflict of interests was declared by the authors.
The impact of various options of the prenatal informational preparation on the success of breastfeeding children
Authors:   Ukrainian Academy of Breastfeeding Medicine, Kharkiv, Kirsanova T.O. , Barska L.Y. ,   Ukrainian Academy of Breastfeeding Medicine, Kharkiv, Uzak I.O. ,   Ukrainian Academy of Breastfeeding Medicine, Kharkiv, Fadieieva A.O. ,   Ukrainian Academy of Breastfeeding Medicine, Kharkiv, Fedorenko O.V. ,   Ukrainian Academy of Breastfeeding Medicine, Kharkiv
Published: December 2024

Breastfeeding definitely has many benefits for the baby, the mother, and the family in general.
Aim - to study the impact of various methods of prenatal preparation on breastfeeding.
Materials and methods. The survey was conducted of 578 families that gave birth to children in the last 10 years. Families were divided into 8 groups depending on how they prepared for the birth of a child.
Results. Most had children in their first two years. During pregnancy, they more often planned to breastfeed. A third planned to breastfeed until 1-2 years. The chance that they would plan to breastfeed for 6 months was 5.4 times higher in the first group compared to the third, 4.3 times higher in the second versus the third. Most children received supplementation before breastfeeding at least once, most often formula. 80% first gave supplementation in the maternity hospital compared to the total number of families that supplemented with formula. The chance of giving formula in the maternity hospital was 2.5 times higher than not giving at all in the first and second groups. 2/3 had problems with breastfeeding, the smallest chance in the fifth group. 70% sought help when problems first arose, most often in the fourth and fifth groups. Most of all, they turned to lactation consultants or doctors. Half believed that they could be helped. The chance of being able to help in the fourth group is 33 times greater than in the first, 17 times greater than in the second, and 68 times greater than in the eighth.
Conclusions. Most parents, regardless of the preparation level for the childbirth or without preparation at all, have plans to breastfeed their children, but the more information the family receives before the birth, the less likely: the child will receive supplemental formula; that there will be a problem with breastfeeding; the family is more likely to: seek help; that they will search help from a qualified specialist; that breastfeeding will last longer. The more the family is aware of issues related to BF during pregnancy, the more successful BF will be after the baby is born.
The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of all participating institutions. The informed consent of the patient was obtained for conducting the studies.
No conflict of interests was declared by the authors.