bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimization of an Innovative Design System for Han Embroidery Dresses Based on Image Matching Method
Authors: Liu Wenlin
Published: October 2024

With cultural confidence emerging as a significant trend in national development, this study underscores the importance of comprehending the cultural essence of Han embroidery attire. Understanding and advancing Han embroidery not only enriches its heritage but also elevates its cultural prominence and fosters the training of future custodians. Through an examination of the historical trajectory of Han embroidery, this paper introduces an innovative design approach grounded in multimedia information gathering techniques. By advocating for increased attention to Han embroidery elements in attire, the study aims to stimulate broader interest in its design and application. Embracing cultural confidence as a guiding principle, the research delves into the nuances of innovative Han embroidery gown design, spanning color, pattern, and style considerations. Through this inquiry, the paper seeks to offer insights that expedite and enhance the evolution of Han embroidery design.
Effects of Innovative Technologies on Gender Disparity and the Future of Work
Authors: Alao Abiodun , Brink Roelien , Simelane Sibusiso , Abubakre Abosede O.
Published: October 2024

The Fourth Industrial Revolution (4IR) has prompted organizations to embrace digital transformation, demanding that employees possess ICT technical skills to boost productivity. In developing countries, a lack of ICT education exacerbates high youth unemployment, particularly among gender-disadvantaged individuals who struggle to secure jobs requiring digital literacy. This study investigates the factors contributing to the gender disparity of youth unemployment in South Africa. The study adopted the Technology Acceptance Theory to guide the study. The quantitative method was used for the data collection process using Google Forms to draft a questionnaire that was distributed to respondents online. The study results show the importance of ICT technical education to improve youth employment prospects and recommend that policymakers implement ICT skills development initiatives to mitigate youth unemployment.
Electronic Docket Adoption in Rural Police Stations
Authors: Agbeyangi Abayomi O. , Lukose Jose M.
Published: October 2024

The adoption of electronic record management systems in rural policing presents significant challenges, impacting case management and service delivery. This study investigates the barriers hindering the implementation of electronic docket systems in rural police stations, focusing on the Amatole District Municipality in the Eastern Cape, South Africa. Data from 37 police officers across six rural stations was analysed using descriptive statistics and machine learning techniques. The descriptive statistics results reveal that while a considerable number of officers acknowledge the potential benefits of electronic docket systems, manual case docket management persists due to various barriers. The decision tree model analysis achieved promising results with an accuracy of 75%, precision of 100%, recall of 66.7%, and an F1 score of 80%. These results revealed that usability and perceived efficiency are key predictors of adoption. The study suggests strategic interventions to enhance operational efficiency and service delivery in rural police stations.
Analysis of Relationships Between Business Domains and Technical-Skill Requirements for Data Analysts
Authors: Zhang Jin , Le Taowen , Chen Jianyao , Zhao Yiming
Published: October 2024

As growth of the data analytics field continues, more and more academic departments and professional training programs are offering skill training to potential data analysts. However, not all business domains require their data analysts to possess the same sets of technical skills. Based on over 2,500 data-analyst job advertisements posted on LinkedIn and utilizing subject analysis, cross-tabulation analysis, heat map, Kruskal-Wallis test, and Kappa test, this study examined relationships between various business domains and the technical skills required for data analysts within the respective business domains. Among many findings, the study discovered noteworthy disparities among the business domains concerning their requirements of technical-skill sets for data analysts. The findings of this study offer valuable insights to educators and potential data analysts.
The ethical aspects of the drug problem
Authors: De Rosa Giuseppe
Published: October 2024

The drug problem has many aspects. One of the most important is the ethical one. In fact, morality concerns the drug problem from a fourfold point of view: from the point of view of production, trade and dealing; from the point of view of consumption; from the point of view of the treatment of drug addicts; from the point of view of drug ‘liberalisation’.
The moral question of drug use: content and method
Authors: Sgreccia Elio
Published: October 2024

Not available.
Specific receptor drugs in the therapeutic strategy of opioid addiction
Authors: Preziosi Paolo
Published: October 2024

Not available.
Family and drugs: considerations of a sociologist
Authors: Burgalassi Silvano
Published: October 2024

Modern reality and the realisation of the vastness and depth of social problems have long since oriented the great mass of scholars of the so-called ‘human sciences’ away from considerations pertaining to the social sphere and into that of macra processes.
Title not available
Authors: Anonimo
Published: October 2024

Not available.
The surgeon and congenital handicaps
Authors: Calisti Alessandro
Published: October 2024

Surgery, and in particular paediatric surgery, with the various specialities that originated from it, is called upon to treat numerous congenital malformative conditions responsible for anatomical and functional handicaps.
The Association of Down Children
Authors: Razzano Enzo
Published: October 2024

The Down's Children's Association is not a welfare organisation, but for assistance it tries to collaborate as best it can with existing structures; it is instead an organisation for collecting and disseminating information on Down's syndrome (mongolism); for supporting parents, doctors, teachers, social and health workers in general; for promoting studies and research; for continuous updating; for consultancy at all levels. It may also be added that it is currently considered by many to be in the vanguard for the modernity and functionality of its approach.
Human rights and genetic engineering: legal aspects
Authors: Fiori Angelo , Grassi Aldo
Published: October 2024

The topic, in its legal aspects, draws the attention of our society - which is asking itself about the future - not only to the need to know the current state of research and applications of genetic genius, but also, indeed above all, to the opportunity to attempt some anticipations of ‘tomorrow’, anticipations that help to plan for the future.
Official pronouncement of the Holy See on euthanasia
Authors: Visser Jan
Published: October 2024

On 5 May 1980 the Supreme Authorities of the S.C. for the Faith signed a Declaration on Euthanasia with the approval and mandate of the Holy Pontiff, but it was published in L'Osservatore Romano on 26 June, when in Urbe ‘calores maximi esse solent’, and all over the world journalistic activity was slowed down due to the holidays; there was no presentation in the press room which documents of this kind usually enjoy.
Abortion in Taranto
Authors: De Benedetto Francesco
Published: October 2024

Availing ourselves of the collaboration of a student from the School of Social Work, admitted as a trainee in the obstetrics-gynaecology department of a Taranto regional hospital, where abortions are performed in application of law 194, we carried out a survey on a total group of 150 women randomly selected from those undergoing the termination of pregnancy.
The theodicies of Hans Jonas and Jürgen Moltmann: Proposing an alternative reformed angle
Authors: Vorster Nico
Published: October 2024

Auschwitz had a profound impact on the theological landscape. It led to God’s lordship, goodness and power being put on trial. If God exists and if he is a good and powerful God, why did he not intervene to stop the atrocities committed during the Holocaust? The theologies of the Jewish philosopher Hans Jonas and the Christian theologian Jürgen Moltmann were decisively structured by these questions.Contribution: This article compares the theodicies of these two influential thinkers within the Jewish and Christian traditions by analysing their concepts of God, the nature of the cosmos and human history as well as their respective views on God’s response to suffering. Despite showing appreciation for profound insights, this article points out impasses in their arguments. Drawing on a reformed approach to the question, the article concludes that the anthropodicy question is the real elephant in the room, not the theodicy question. Instead of asking questions about God’s goodness, Reformed theology posits the incomprehensibility of human beings turning against God. We must ask: How does it happen that a self-conscious being possessing innate moral capacities, such as moral emotions and vicarious intersubjective capabilities, rebels against God and engage in atrocious acts? Seen from this perspective, the theodicy question seems to be undergirded by the human propensity to moral disengagement and blame-shifting. Perhaps, instead of putting God on trial, humans must resort to introspection.
Relationship between implementation of sustainable human resource practices and corporate market value
Authors: Magau Mpho D.
Published: October 2024

Orientation: The sustainable development goals (SDGs) were the context for examining the human resource (HR) expertise required in the boardroom. Achievement of SDGs depends on how boards are structured and whether members have the appropriate expertise to implement key HR practices to maximise corporate market value.Research purpose: This study aimed to critically examine the mediation effect of HR expertise in the boardroom on the relationship between implementation of human resource practices (HRPs) and market value.Motivation for the study: The study investigated whether HR expertise in the boardroom contributes to the implementation of key HRPs to achieve employee-related SDGs.Research approach/design and method: A randomised experimental design was performed through a bootstrap procedure to examine mediation. Data were collected from corporate annual reports through a self-constructed measurement instrument or disclosure index.Main findings: Overall, no evidence of a mediation was found, except in the case of HR expertise in the board and HR and/or remuneration committee, which yielded a statistically significant mediation effect on the implementation of some initiatives with confidence intervals close to zero.Practical/managerial implications: Human resource expertise in the boardroom plays a crucial role in achieving the SDGs, and the lack thereof affects the company’s market value. Therefore, the board of directors (BoDs) must prioritise sufficient HR expertise in the relevant structures to facilitate implementation of HRPs to achieve the SDGs.Contribution/value-add: This study is the first attempt of its kind in South Africa, and the results demonstrate the absence of a mediation effect, signalling that a lack of HR expertise in the boardroom could affect organisations’ achievement of the SDGs.
The Saudi thoracic society guidelines for vaccinations in adult patients with chronic respiratory diseases
Authors: Al Ghobain Mohammed , Farahat Fayssal , Zeitouni Mohammed , Alsowayan Waleed , Al-Awfi Sultan , AlBarrak Ali , Al-Basheri Shareefah , Alhabeeb Fatmah , Alhamad Esam H.
Published: October 2024

Adult patients with chronic respiratory diseases (CRDs) are considered high risk group who are more likely to experience worse clinical outcomes if they acquire viral or bacterial infections. Vaccination is the best preventive tool to reduce the risk of infection and disease occurrence and to reduce the level of severity of complications associated with the various vaccine-preventable infections. These guidelines were developed by the Saudi Thoracic Society task force to emphasize the critical importance of improving the vaccine coverage rates in adult patients with CRD. They are intended to serve as a reference for healthcare practitioners managing CRD patients. The guidelines aimed to review the current knowledge related to vaccination efficacy in adult patients with CRD, based on the recent evidence and recommendations. Integrating the administration of the recommended vaccines in routine healthcare, such as during outpatient visits or before hospital discharge, is crucial for improving the vaccination rates in high-risk patients. The key strategies to address this public health priority include simplifying vaccination guidelines to enhance their accessibility and implementation by healthcare providers, increasing awareness in both the patients and healthcare providers that vaccines are not only intended for children. Additional strategies include maintaining continuous surveillance and advance research to discover novel vaccines. This approach aims to expand the range of preventable diseases and improve overall health and well-being. Vaccine hesitancy remains a significant challenge that necessitates a clear understanding of the community concerns. Providing appropriate education and communication, as well as addressing these concerns, are the crucial steps toward improving vaccine acceptance and uptake. By implementing these guidelines and multifaceted strategies, healthcare systems can optimize vaccine coverage and protection for patients with CRD, reduce the burden of vaccine-preventable complications, and improve the clinical outcomes in this vulnerable population.
Real-time dynamic navigation way forward to restoring smiles
Authors: Jain Sanjay , Poulose Mariam , Nagy Katalin
Published: October 2024

This case report describes the “Fast and Fixed” dental implant procedure, used to replace failing dentition with a fixed prosthesis that is supported by only four dental implants in each arch. This immediate loading protocol is designed to provide a more stable and permanent solution for individuals who have lost a significant number of teeth or are facing complete tooth loss. Dynamic navigation involves using computer-guided technology to plan and execute dental implant surgery in real time. In the context of a full-mouth implant restoration, dynamic navigation helps the surgeon to precisely determine the optimal prosthetic driven locations of the dental implants. This technology not only improves accuracy, reduces the risk of errors, but can contribute to better treatment outcomes in challenging cases of full-mouth implant-based rehabilitation.
Effect of Work-related Stress on Breast Milk Feeding Beyond 6 Month of the Baby, among the Nursing Personnel: A Cross Sectional Study
Authors: Biswas Daliya , Rout Arup Jyoti , Saha Tushar Kanti
Published: October 2024

Background:

The largest drop in continuing breast milk feeding occurs with the return of the lactating mothers to work. Stress amongst the working mothers affects milk production. Nursing is a stressful job and work-related stress impacts nurses’ health-related quality of life. The effect of work-related stress on breast milk feeding beyond 6 months of the baby amongst nursing mothers is an unexplored area.

Objectives:

(a) To assess the work-related stress, (b) to estimate the proportion of discontinued breast milk feeding beyond 6 months of the baby and (c) to find out the association (if any) between work-related stress and discontinuation of breast milk feeding beyond 6 months, amongst the nursing personnel of Siliguri subdivision of Darjeeling district.

Materials and Methods:

A cross-sectional study was carried out amongst the eligible study population using a work-related stress questionnaire. Chi-square test was done as a test of association and binomial logistic regression was used to find out the adjusted odds ratio (AOR).

Results:

Work-related stress was present in 62.4% of the respondents, while 70.9% had discontinued breastfeeding beyond 6 months. 79.5% of respondents with work-related stress had discontinued breastfeeding. Nursing staffs having work-related stress had higher odds of discontinuing breastfeeding (AOR: 3.682; confidence interval: 1.4035–9.659).

Conclusion:

Work-related stress is present in a large proportion of nursing staffs and many of them have discontinued breast milk feeding beyond 6 months of age of their babies, which is influenced by work-related stress.
Telemedicine in Diabetic Retinal Screening: Pre- and Post-COVID-19 Challenges a New Perspective
Authors: Baig Arshi , Zafar Azhar
Published: October 2024

Telemedicine in ophthalmology has been around for decades and has been successful with its use in diabetic retinal screening in countries like the UK (with the introduction of the UK National Diabetic Eye Screening Programme in 2003). However, most telemedicine, in the field of diabetic retinopathy, has largely been reliant on human graders for triage purposes. With the advent of COVID-19, patients with chronic conditions, such as diabetes, were disproportionately affected. The pandemic also caused significant rise in patients on waiting lists. Before the pandemic, there have been studies illustrating the use of artificial intelligence (AI) to analyse images obtained from patients screened for monitoring of their diabetic retinopathy. The image analysis by AI and deep-learning algorithms offers insight into the future of screening in diabetes. The transition, from the use of human graders in teleophthalmology to the use of AI-based image analysis has the potential to screen a wider cohort of patients, thereby tackling waiting lists awaiting screening which has lengthened since after COVID-19. It is therefore vital to understand the role of AI in screening diabetic retinopathy patients, from a patient-acceptability, cost-effectiveness and reliability perspective as, this offers potential answers to streamline the screening process further.
Chromogenic versus Conventional: A Comparative Analysis for Uropathogen Detection in Paediatrics at a Tertiary Centre
Authors: Agarwal Manish Kumar , Baveja Sujata , Joshi Anuja
Published: October 2024

Background:

Urinary tract infections (UTIs) are a common bacterial infection in children, often presenting with non-specific symptoms such as undiagnosed fever and gastrointestinal issues. Early detection and treatment are essential to reduce morbidity and mortality.

Aims:

This study aimed to compare conventional culture media with chromogenic culture methods for detecting uropathogens and to identify the causative pathogens in pediatric patients at a tertiary care hospital.

Patients and Methods:

The study was conducted over 18 months in the department of microbiology at a tertiary care hospital, involving 400 pediatric patients who met the inclusion and exclusion criteria. Urine samples were collected and promptly processed, then inoculated on various media, including blood agar, MacConkey agar, cysteine lactose electrolyte deficient agar, and UTI chromogenic agar. Bacterial isolates were identified using standard bacteriological techniques, and their antimicrobial susceptibility was determined using the Kirby–Bauer disk diffusion method.

Results:

Escherichia coli was the most prevalent Gram-negative organism detected on both conventional and UTI chromogenic agar. UTI chromogenic agar showed greater efficiency in isolating and presumptively identifying uropathogens. E. coli isolates demonstrated high susceptibility to key antimicrobial agents. Enterococcus spp. were completely sensitive to vancomycin and linezolid, while nitrofurantoin was effective in 57.14% of cases.

Conclusion:

UTI chromogenic agar is an effective alternative to conventional media, offering advantages in isolating and presumptively identifying uropathogens. Its enhanced sensitivity, particularly for Gram-positive cocci like Enterococcus spp. in mixed cultures, provides valuable support to clinicians for early UTI diagnosis and treatment decisions.
Comparison of discussion-based and simulation-based learning methods using the Gas Man® on knowledge of the uptake and distribution of inhalation anesthetics of anesthesia resident: A randomized controlled trial
Authors: Heriwardito Aldy , Ramdhoni Lalu , Ramlan Andi A. W. , Perdana Aries , Hidayat Jefferson
Published: October 2024

Background and Aims:

Inhalation anesthetics is basic knowledge that must be mastered by an anesthesiologist. Lack of competencies can result in higher morbidity and mortality in anesthesiology practice. Various learning methods were developed to improve understanding and retention. With the advancement of technology, the utilization of screen-based simulation (SBS) using applications is common, such as the Gas Man® application, to help students understand physiology, pathophysiology, and kinetic inhalation anesthetic agents. The primary objective of this study was to compare the knowledge improvement of anesthesia residents between the simulation-based and discussion-based learning methods on the uptake and distribution of anesthetic inhalation. The secondary objective was to compare the satisfaction levels of participants in both learning methods.

Material and Methods:

This study is a randomized controlled trial involving anesthesiology and intensive care residents from the Faculty of Medicine, Universitas Indonesia (FKUI) 2022–2023. The participants were randomized into two groups (simulation and discussion groups). A senior attending anesthesiologist led the discussion. The participants answered a pretest, followed by a 1-hour lecture about inhalation gas. Lastly, participants answered a posttest and filled in the satisfaction survey. Statistical analyses used the Mann–Whitney test to compare the two groups. The Wilcoxon test was used to compare the knowledge improvement between the two groups.

Results:

Thirty-eight residents underwent simulation-based (n = 19) and discussion-based (n = 19) learning methods. The simulation group demonstrated a median (interquartile range) posttest score of 80 (76.67–83.33) compared with the discussion group with a score of 50 (40–66.67) (P value <0.05). More than half of the participants in both groups answered “satisfied.”

Conclusion:

The simulation-based learning method using the Gas Man® application performed better than the discussion-based learning method on increasing knowledge of the uptake and distribution of inhalation anesthetics in anesthesia residents.
Adenoid Cystic Carcinoma of the Lacrimal Gland
Authors: Chaaya Celine , El Haddad Georges , Abdul Karim Fadi , Abou Daher Sarah
Published: October 2024

Purpose:

To explore the various aspects of adenoid cystic carcinoma of the lacrimal gland (LACC), including its clinical features, presentations, genetic factors, as well as current and potential future treatment options.

Methods:

A thorough exploration of the literature was conducted by extensively searching the PubMed database. A total of 68 articles with a primary focus on adenoid cystic carcinoma were selected.

Results:

LACC is the most frequent malignant epithelial tumor of the lacrimal gland. It is characterized by the symptoms such as pain, progressive swelling of the eye, double vision, and bulging of the eye. Although LACC is a rare tumor, early detection and appropriate treatment are crucial due to its aggressive nature which includes high recurrence rate and a significant risk of mortality. The primary treatment options for LACC involve a wide range of surgical procedures, including orbitotomy, exenteration, and cranio-orbital resection. Neoadjuvant intra-arterial chemotherapy represents the paradigm shift in the treatment of LACC enhancing patient survival when compared to conventional treatments.

Conclusion:

The existing literature emphasizes the importance of identifying prognostic factors that can guide treatment decisions and enhance the outcomes for patients with LACC.
Development and validation of a questionnaire to evaluate attitude about menstruation among adolescent girls
Authors: Tahiliani Sanjana Sanjay , Bulbuli Ashwini S.
Published: October 2024

CONTEXT:

Cultural influences promote secrecy, making it difficult for girls to openly discuss menstruation. This further impacts their attitude and emotional well-being. Showing adolescent girls the reality of menstruation would give them a clear understanding of menstruation.

AIMS:

The aim of this study was to develop and validate a questionnaire to evaluate attitude about menstruation among Adolescent girls.

SETTINGS:

Adolescent girls in Belagavi city.

DESIGN:

Exploratory study.

SUBJECTS AND METHODS:

The Adolescent Menstrual Attitude Inventory Questionnaire (AMAI-Q) was developed using a multistep method divided into two phases. Phase I: Concept elicitation, which includes identification of domains and item generation; and expert input, which includes content validation. Phase II: Pilot testing of 11 adolescent girls and reliability calculation using Cronbach’s alpha.

STATISTICAL ANALYSIS USED:

The content validity index of the questionnaire was calculated, and the reliability of the questionnaire was assessed using Cronbach’s alpha.

RESULTS:

The content validity of the questionnaire was tested using the content validity index, which was found to be 0.911. Reliability was assessed using Cronbach’s alpha and was found to be 0.818, indicating good reliability.

CONCLUSIONS:

The proposed questionnaire, AMAI-Q is well-validated, easy to administer, and has good reliability. AMAI-Q will be a suitable scale to evaluate attitude about menstruation among adolescent girls.
Electrophysiological evidence of dry needling efficacy on spasticity in poststroke patients: A randomized control trial
Authors: Kamble Sanjivani Nikhil , Baxi Gaurang D. , Palekar Tushar J.
Published: October 2024

CONTEXT:

Therapists use dry needling (DN) to treat myofascial trigger points and various pain conditions. Need for study: A gap analysis showed that more information about how DN works on spastic muscles through alpha motor neurofiring and what role it plays in clinical and functional outcomes. Currently, the objective evidence for the usefulness of DN in neurological diseases is required.

AIMS:

The purpose of this research was to examine how DN affects spasticity in stroke patients using the H reflex and a Modified Tardieu Scale (MTS).

SETTINGS AND DESIGN:

We conducted a randomized controlled trial. We randomly assigned 81 stroke survivors to one of two groups: one group underwent six sessions of DN over the muscles with conventional treatment, whereas the other group received conventional care. We assessed spasticity using the H reflex and the MTS. We analyzed all outcome measures before, after, and 2 weeks later names as H1, H2, H3 and T1, T2, and T2 receptivity.

RESULTS:

After the intervention, people who received DN had improvement in spasticity. H3-H1 is statistically significant (P = 0.42) in the experimental group against the control group. T3-T1 and T2-T3 are statistically significant (P = 0.00) in the experimental group compared to the control group.

CONCLUSIONS:

The DN is effective for lowering spastic muscle tone and local muscle stiffness. This could be because DN diminishes the nodular zone of spastic muscle and reduces the firing of alpha motor neurons. These findings are very promising in terms of lowering spasticity.
Survival rate comparisons of angioembolization and neoadjuvant targeted therapy on unresectable renal cell carcinoma patients: A systematic review
Authors: Muhammad Rifqi Yanda , Nurfajri Derri Hafa , Dahril Dahril , Ismy Jufriady
Published: October 2024

Objective:

Renal cell cancer (RCC) is the most typical form of kidney cancer in adults, which accounts for 80% to 85% of all primary renal neoplasms. RCC develops inside the renal cortex. This study aimed to systematically review the survival rate of patients treated with targeted therapy and/or RC. Surgery is the standard therapy for RCC, even though after surgery, 20%–40% of patients with localized RCC would experience distant metastases. Metastases or large RCC are not amenable to surgery. Unresectable RCC can be treated palliatively with angioembolization or neoadjuvant therapy. This study aims to review the survival rate comparisons of angioembolization and neoadjuvant targeted therapy on unresectable renal cell carcinoma.

Methods:

A thorough search across databases such as PubMed, Cochrane Library, and ProQuest was conducted for articles published from 2018 to 2023. To uphold research integrity, duplicates, reviews, and incomplete articles were excluded, ensuring only pertinent and original research findings for subsequent analysis.

Results:

Database search yielded 247 articles, which were systematically eliminated, leaving 6 relevant articles. Analyzed articles showed the overall survival of patients treated with angioembolization and neoadjuvant agents.

Conclusion:

Unresectable RCC can be treated palliatively with angioembolization. Angioembolization may improve clinical effectiveness and lessen side effects by boosting local concentrations of drugs. Drug-eluting bead transarterial chemoembolization is a novel embolization option that can embolize the arteries that feed the tumor and cutoff the blood supply to the tumor. Sunitinib, the most studied medicinal agent, was found to have higher effectiveness when combined with angioembolization.
Inverse problems for evolutionary quasi-variational hemivariational inequalities with application to mixed boundary value problems
Authors: Peng Zijia , Yang Guangkun , Liu Zhenhai , Migórski Stanislaw
Published: October 2024

The aim of this paper is to examine an inverse problem of parameter identification in an evolutionary quasi-variational hemivariational inequality in infinite dimensional reflexive Banach spaces. First, the solvability and compactness of the solution set to the inequality are established by employing a fixed point argument and tools of non-linear analysis. Then, general existence and compactness results for the inverse problem have been proved. Finally, we illustrate the applicability of the results in the study of an identification problem for an initial-boundary value problem of parabolic type with mixed multivalued and non-monotone boundary conditions and a state constraint.
Tiliroside protects against diabetic nephropathy in streptozotocin-induced diabetes rats by attenuating oxidative stress and inflammation
Authors: Shang Yan , Yan Cai-Yun , Li Hui , Liu Na , Zhang Hui-Feng
Published: October 2024

BACKGROUND

Diabetic nephropathy (DN), affecting half of diabetic patients and contributing significantly to end-stage kidney disease, poses a substantial medical challenge requiring dialysis or transplantation. The nuanced onset and clinical progression of kidney disease in diabetes involve consistent renal function decline and persistent albuminuria.

AIM

To investigate Tiliroside's (Til) protective effect against diabetic nephropathy (DN) in rats under diabetic conditions.

METHODS

Five groups of six rats each were included in this study: Rats treated with DMSO by intraperitoneal injection as controls, those treated with STZ by intraperitoneal injection, those treated with STZ + Til (25 mg/kg body weight [bwt]) or Til (50 mg/kg bwt), and those treated with anti-diabetic medication glibenclamide (600 μg/kg bwt). Biochemical markers, fasting blood glucose, food intake, kidney weight, antioxidant enzymes, inflammatory and fibrotic markers, and renal injury were monitored in different groups. Molecular docking analysis was performed to identify the interactions between Til and its targeted biomarkers.

RESULTS

Til significantly reduced biochemical markers, fasting blood glucose, food intake, and kidney weight and elevated antioxidant enzymes in diabetic rats. It also mitigated inflammatory and fibrotic markers, lessened renal injury, and displayed inhibitory potential against crucial markers associated with DN as demonstrated by molecular docking analysis.

CONCLUSION

These findings suggest Til's potential as a therapeutic agent for DN treatment, highlighting its promise for future drug development.
Precision Seismicity of the San Andreas Fault System in Central California: Insights into Active Tectonics and Earthquake Physics
Authors: Ellsworth William L.
Published: October 2024

Since the late 1960s, seismicity of the San Andreas Fault system in central California has been under intense observation by U. S. Geological Survey’s Northern California Seismic Network (NCSN). Designed to provide accurate focal depth control and a low magnitude of catalog completeness, the network maps fault, both large and small across the full breadth of this 400-kilometer-long portion of the plate boundary, including many that are known only from their seismicity. Beginning in 1984, with the advent of routine digital recording, new opportunities were created to significantly enhance the spatial resolution of seismicity. This led to the co-evolution of method that take full advantage of digital waveforms and new insights into the nature of seismicity and faults. Collectively referred to as precision seismicity, discoveries included repeating earthquakes and highly organized and stable distributions of seismicity on major faults. Long term observation of seismicity before and after the six largest earthquakes over the last half-century underscore the outstanding challenges for earthquake predictability and theories of earthquake nucleation.
An Unambiguous Signature of Pore Fluid Aftershock Triggering in the Landers Earthquake Sequence
Authors: Beroza Gregory , Zanzerkia Eva E.
Published: October 2024

Aftershocks within an extensional fault discontinuity of the 1992 Landers, California earthquake rupture occurred at an approximately constant rate for over three years following the mainshock. This contrasts with most of the rest of the aftershock sequence, and aftershock sequences in general, for which aftershock rates decay following Omori’s law. The protracted aftershocks in the fault discontinuity can be understood if pore fluids are present at seismogenic depths and trigger seismicity as they flow to equilibrate pore pressure during the transition from the immediate, undrained to the eventual, drained condition. Changes in pore fluid pressure modulated by changes in the mean normal stress provide a clear and unambiguous signature of fluid effects in earthquake triggering. If this result generalizes to other settings, it suggests a predictable time-dependent component to the pattern of aftershock triggering not accounted for in models of Coulomb static stress triggering.
What Socrates Learned From Parmenides. Part 2. Hypothesis, Antilogy, and Philosophical Self-Defense in the Phaedo
Authors: Larivée Annie
Published: October 2024

My first study identified the cognitive abilities and argumentative skills developed by the gymnasia presented in Plato’s Parmenides. Since the correspondence with the intellectual virtues Socrates displays in other dialogues is too remarkable to be a coincidence, I concluded that Socrates must have trained with Parmenides’ eightfold routine in his youth. My second study supports this conclusion by drawing attention to textual evidence found in the Phaedo. The autobiographical account Socrates shares in that dialogue indicates how the gymnasia impacted his intellectual development, mostly through the action of hypothesizing. This strategic move used by the Eleatics transformed the originally sectarian way So- crates related to Forms and enabled him to protect his theory from attacks in a secure yet non-dogmatic way.
Zeno and Antilogic
Authors: Balla Chloe
Published: October 2024

This paper sheds light on Plato’s represen- tation of Zeno in the Phaedrus as a master of antilogic. It examines the evidence in the Phaedrus drawing attention to a certain distribution of labour between the followers of Palamedes, who practice antilogic, on the one hand and those of Nestor and Odysseus, who prac- tice logography, on the other. I suggest that the reason for which Plato prefers to associate Zeno with antilogic rather than Protagoras, who might strike us as an obvi- ous choice, is that the former, unlike the latter, would serve the purposes of his Socratic apologetics, remov- ing from his teacher the reputation that Aristophanes’ Clouds had bequeathed him. This reading ties in with and draws support from Zeno’s remarks concerning the nature of his book in the Parmenides, a dialogue that Plato intends us to understand as a prequel that—again along the lines of an apologetic agenda—claims Socrates’ philosophical pedigree establishing his ties with the Eleatic tradition.
Prospects of autonomous railway transport development
Authors: Popov P. A. , Ozerov A. V. , Marshova A. S.
Published: October 2024

The implementation of unmanned train control systems offers a number of advantages, such as increasing the capacity of railway lines and traffi c volumes, reducing the ‘human factor’, as well as reducing operating costs. The paper considers the challenges arising from the use of automatic train control systems, and presents the prospects for the implementation of automatic technologies in railway transport for various railway systems. The social and economic aspects of changing professional activities in railway transport are described. Grades of automation applicable to surface urban railwaytransport are presented. The issues of proving the functional safety of machine vision systems as part of the train traffic control system and determining their level of safety completeness are discussed. Examples of railway transport automation in Russia and other countries are given. Basic scenarios of automatic control system operation describing normal and abnormal situations are formulated. In conclusion, the levels of technological readiness of the reviewed solutions in the fi eld of train traffic automation are defi ned. The tasks faced by railway companies in implementing these technologies are outlined, and possible ways of overcoming obstacles to the introduction of automatic systems are proposed, taking into account the current political situation.
The Correlation Between Adherence to Personal Protective Equipment and Incidents Involving Construction Workers at the Bali Hospital Project
Authors: Saputra Adi , Nataya Stanita
Published: October 2024

Work accidents are unwanted events that harm people, cause damage to property, and work processes. In the construction sector, the work accident rate in Indonesia reaches 32%. This research aims to determine the relationship between compliance with the use of personal protective equipment (PPE) with the incidence of work accidents in construction sector workers at Bali International Hospital Sanur managed by PT PP (Persero) Tbk. This research used a quantitative method with a cross-sectional design. The research population was all construction workers in the Bali International Hospital Sanur project as many as 286 people, with random sampling techniques. The instrument used in data collection was a questionnaire, and data analysis was carried out univariate and bivariate using the Chi-square test. The results showed a relationship between the use of safety helmets and the incidence of occupational accidents in construction workers at Bali International Hospital Sanur by PT PP (Persero) Tbk (p = 0.11). The implication of this research is the importance of compliance with the use of PPE in preventing work accidents in the construction sector.
Analisis Faktor Eksternal dan Internal terhadap Perilaku Konsumtif Mahasiswa Jurusan Ilmu Pengetahuan Sosial
Authors: Suryawati Ni Kadek , Hasanah Mahmudah , Rahmattullah Muhammad , Bahar Syaripudin
Published: October 2024

The purpose of this study is to evaluate the influence of internal and external factors on consumptive behavior. This problem is focused on the high level of consumptive behavior among students caused by factors that come from outside and within the individual. The research method used is descriptive research with a quantitative approach. The sample was taken using the Purposive Random Sampling technique as many as 271 students of the Department of Social Sciences. The data collection method uses questionnaires, observations, and documentation from students as well as references from journals, books, and other relevant sources. Descriptive statistical analysis, classical assumption test, multiple regression analysis, partial test (t-test), simultaneous test (f-test), and determination coefficient test (R2) were used to analyze the research data. The results showed that there was a multiple regression equation showing that Y = 5.026 + 0.438X1 + 0.267X2. Based on the hypothesis test, the significance value (Sig) of 0.000 is greater than the probability of 0.05, so it can be concluded that the external factor (X1) and internal factor (X2) have a significant and positive influence on the consumptive behavior (Y) of students of the Department of Social Sciences.
Pandangan Masyarakat Aceh tentang Penggunaan Ganja
Authors: Muttaqien Muhammad Zainul
Published: October 2024

This study aims to explore the views of the Acehnese people regarding the use of marijuana, with a special focus on the perspectives of traditional leaders and clergy in the region. Aceh, known for its strict application of sharia law, has a distinctive view of prohibited substances, including marijuana. This research method uses a qualitative approach with in-depth interview techniques with traditional leaders and clergy as well as literature studies to strengthen their views on the legality, social impact, and moral implications of cannabis use. The results of this study show that medically, marijuana can overcome long-term pain, mental health problems, slow the development of cancer cells, and improve symptoms of epilepsy and multiple sclerosis. However, there are health risks such as mental health problems, testicular cancer, and respiratory diseases if used. In Indonesia law, marijuana is considered a drug with a high addictive effect and is prohibited from use. By teaching the community and working with law enforcement, Acehnese traditional and religious leaders play an important role in preventing marijuana abuse. In general, although marijuana has potential medical benefits, marijuana use in Indonesia must continue to be controlled and restricted to prevent abuse. If the legalization of medical marijuana is discussed, the benefits and risks should be carefully considered, with strict regulation to reduce its adverse effects.
Our Experience with the Use of Dexmedetomidine in the Postoperative Period in Surgical Patients
Authors:   Azerbaijan Medical University, EM Nasibova
Published: October 2024

The problem of treatment of postoperative pain syndrome remains very relevant, despite the large selection of analgesics of various types, as well as the development of various methods of pain relief. Providing complete pain relief after surgery remains a desirable but not always achievable goal. According to the literature, from 50 to 80% of patients who underwent surgery suffer from severe pain in the postoperative period. Purpose of the study: To study the efficacy and safety of pain relief technique using intravenous prolonged infusion of dexmedetomidine in combination with NSAIDs and opioids in the early postoperative period in surgical patients. Material and Methods: The study was conducted in the surgical clinic of the AMU. The clinical study included 156 patients aged 10 to 35 years after elective abdominal surgery (cholecystectomy, hemicolectomy, etc.). To assess the adequacy of analgesia and the need for the introduction of narcotic analgesics, we used a visual analogue scale (VAS) of pain intensity. Results of the study: The criterion for the effectiveness of analgesia performed in the postoperative period was the reduction of pain according to VAS to 3 and below. The criterion for the introduction of opioids was considered to be an increase in the intensity of pain according to the VAS up to 6-7 points. Mean pain scores between groups at various stages are presented. Conclusions: The use of prolonged intravenous infusion of dexmedetomidine in combination with non-narcotic analgesics in the early postoperative period in patients undergoing elective abdominal surgery can significantly reduce the need for repeated injections of both non-narcotic and narcotic analgesics, improves patient comfort and safety.
Prevalence of Household Food Insecurity and its Associated Factors in West Gojjam Zone, Ethiopia. A Community- based Cross Sectional Study
Authors:   School of Public Health, College of Medicine and Health Science, Bahir Dar University (BDU), Bahir Dar, Ethiopia, Belayneh Melesse , Makua Memme ,   University of South Africa (UNISA), College of Human Science (CHS), Pretoria, South Africa
Published: October 2024

Background: Food insecurity remains a global social and public health issue affecting households. Divergent trends persisted despite the shift in the frequency of food insecurity in local, regional, and global contexts which needs imitate attention for action by stakeholders. Therefore, This study aimed to determine the magnitude and identify the factors that contribute to household food insecurity in the West Gojjam zone in Northwest Ethiopia.
Structured Concurrency in Java
Authors:   Los Angeles, USA, Jagnik Nilesh
Published: October 2024

Concurrency is vital for high performance software applications. The Java language has support for concurrency but it requires developers to handle execution of concurrent tasks. This adds a learning curve and makes concurrent code harder to read, write and debug. To solve this issue, Java 21 introduces a preview feature called structured concurrency. In this paper, we review the idea behind structured concurrency and discuss how the new language feature works in Java.
Automating Customer Feedback Integration in the Sales Cycle: Enhancing Sales Performance and Accountability through Salesforce and Medallia
Authors:   USA, Konakalla Kiran
Published: October 2024

Effective sales management hinges on understanding and responding to customer feedback throughout the sales cycle. This paper examines a strategy for capturing feedback at each stage of the sales process—pitching, negotiation, contract finalization, and closing. By integrating Salesforce with Medallia, a customer experiences management tool, organizations can automate the collection of feedback, track performance, and enhance accountability. The approach not only improves sales outcomes but also fosters a customer-centric sales strategy, driving continuous improvement and innovation in sales processes.
A Rare Case of Hilar Mass Lesion- Castleman’s Disease
Authors:   NMC Specialty Hospital, Abu Dhabi, United Arab Emirates, Anas Ayoob Muhammed
Published: October 2024

Castleman’s disease (CD) is an uncommon, lymphoproliferative disease that shares common lymph node histological features.