bluuebunny/crossref_metadata_2025 huggingface dataset:
Unique crystallization behavior in zeolite synthesis under external high pressures
Authors: Tan Che , Liu Zhendong , Yonezawa Yasuo , Sukenaga Sohei , Ando Mariko , Shibata Hiroyuki , Sasaki Yukichi , Okubo Tatsuya , Wakihara Toru
Published: January 2020

Hydrothermal synthesis of zeolites under external high pressures generates unique crystallization behaviors that are different from the synthesis under autogenous pressure.
Designing bifuncitonal molecular devices with a metalloporphyrin dimer
Authors: Xia Ying , Shuai Ling , Wang Yiping , Ma Yao , Han Lingyun , Qiu Ming , Zhang Zhenhua , Leung Michael K. H.
Published: January 2020

The metalloporphyrin dimer devices have high spin filtering efficiencies and magnetoresistance ratios exceeding 108%.
Graph theory-based reaction pathway searches and DFT calculations for the mechanism studies of free radical-initiated peptide sequencing mass spectrometry (FRIPS MS): a model gas-phase reaction of GGR tri-peptide
Authors: Lee Jae-ung , Kim Yeonjoon , Kim Woo Youn , Oh Han Bin
Published: January 2020

A new approach for elucidating gas-phase fragmentation mechanisms is proposed: graph theory-based reaction pathway searches (ACE-Reaction program) and density functional theory (DFT) calculations.
Interaction of positronium with dissolved oxygen in liquids
Authors: Stepanov P. S. , Selim F. A. , Stepanov S. V. , Bokov A. V. , Ilyukhina O. V. , Duplâtre G. , Byakov V. M.
Published: January 2020

The interaction of positronium with molecular oxygen dissolved in liquids is experimentally investigated. A computer software has been developed for fitting the positron annihilation lifetime spectra using parameters with clear physical meaning.
Intrinsic electronic and transport properties of graphene nanoribbons with different widths
Authors: Zhang Liuyue , Zhao Jianwei , Cheng Na , Chen Zhidong
Published: January 2020

Except for the narrow ZGNRs, 1-ZGNR and 2-ZGNR, odd ZGNRs possess small current regardless of the bias applied and even ZGNRs have much larger current and behave as a resistor.
Crystallization and single molecule magnetic behavior of quadruple-stranded helicates: tuning the anisotropic axes
Authors: Gao Xingrui , Li Li , Sun Wenbin , Chen Peng
Published: January 2020

Two quadruple-stranded helicates have been prepared, and their unique coordination environment of dinuclear helicates can provide a way to tune the alignment of the anisotropic axes.
Trinuclear ruthenium core-containing polyoxometalate-based hybrids: preparation, characterization and catalytic behavior
Authors: Li Huafeng , He Peipei , Wan Rong , Zou Yan , Zhao Xue , Ma Pengtao , Niu Jingyang , Wang Jingping
Published: January 2020

We report here photoinduced topochemical polymerizations of diacetylene-derivatized compound by the introduction of amide functions as the structure directing agent in solution.
A hydrophilic heterogeneous cobalt catalyst for fluoride-free Hiyama, Suzuki, Heck and Hirao cross-coupling reactions in water
Authors: Sobhani Sara , Hosseini Moghadam Hadis , Skibsted Jørgen , Sansano José Miguel
Published: January 2020

A hydrophilic chitosan-cobalt-Schiff base catalyst denoted as mTEG-CS-Co-Schiff-base was prepared for C–C and C–P cross coupling reactions in water.
Transition metal- and solvent-free double hydroboration of nitriles
Authors: Bedi Deepika , Brar Aneelman , Findlater Michael
Published: January 2020

An operationally convenient, room temperature synthesis of N,N-diborylated amines via hydroboration of nitriles using a commercially available catalyst.
Highly flexible and mechanically strong polyaniline nanostructure @ aramid nanofiber films for free-standing supercapacitor electrodes
Authors: Yin Qing , Jia Hongbing , Mohamed Amel , Ji Qingmin , Hong Liu
Published: January 2020

The excellent integration of high specific capacitance and superior mechanical properties for flexible electrode can be achieved by the combination of aramid nanofiber and polyaniline.
Fabrication of a graphene layer probe to measure force interactions in layered heterojunctions
Authors: Li Jianfeng , Li Jinjin , Jiang Liang , Luo Jianbin
Published: January 2020

We propose a simple method to fabricate a clean and wear resistant graphene layer probe, to directly measure the force interactions in different layered heterojunctions.
From bulk crystallization of inorganic nanoparticles at the air/water interface: tunable organization and intense structural colors
Authors: Vialetto Jacopo , Rudiuk Sergii , Morel Mathieu , Baigl Damien
Published: January 2020

With minute amounts of a surfactant, a variety of nanoparticles self-assemble at the air/water interface into optically active crystalline 2D structures.
One-pot synthesis of 2-azolylimidazole derivatives through a domino addition/A3 coupling/cyclization process under copper catalysis
Authors: Lin Yifan , Li Erfei , Wu Xin , Wang Luyu , Wang Haofeng , Li Xiaoyu , Kang Honglan , Zhou Liejin , Shen Guodong , Lv Xin
Published: January 2020

A novel one-pot approach for the synthesis of multi-substituted 2-imidazolylimidazoles, 2-pyrazolylimidazoles and 2-indazolylimidazoles was developed through a domino addition/A3 coupling/cyclization process under copper catalysis.
Cationic poly-amido-saccharides: stereochemically-defined, enantiopure polymers from anionic ring-opening polymerization of an amino-sugar monomer
Authors: Balijepalli Anant S. , Hamoud Aladin , Grinstaff Mark W.
Published: January 2020

We expand the scope of the PAS methodology and evaluate multiple synthetic routes to generate a regioselectively-functionalized 6-amino carbohydrate polymer sharing key properties with natural polysaccharides, including high water-solubility.
Zener-like electrical transport in polyaniline–graphene oxide nanocomposites
Authors: Dey Animesh Kr. , Kumar Gaurav , Maji Pradip K. , Chakrabarty R. K. , Nandi U. N.
Published: January 2020

The present study includes the fabrication and characterization and an investigation of the electrical transport properties of nanocomposites of n-PANI and graphene oxide (GO).
Simultaneous quantification of five biomarkers in ethanolic extract ofCassia occidentalisLinn. stem using liquid chromatography tandem mass spectrometry: application to its pharmacokinetic studies
Authors: Riyazuddin Mohammed , Husain Athar , Verma Saurabh , Katekar Roshan , Garg Richa , Kumar Sudhir , Satish Sabbu , Maurya Rakesh , Narender Tadigoppula , Chattopadhyay Naibedya , Gayen Jiaur R.
Published: January 2020

Liquid chromatography tandem mass spectrometry was used to develop a bioanalytical method for simultaneous quantification of five biomarkers ofCassia occidentalisL. ethanolic extract to use in oral pharmacokinetics andin vitrostability studies.
Two d10 luminescent metal–organic frameworks as dual functional luminescent sensors for (Fe3+,Cu2+) and 2,4,6-trinitrophenol (TNP) with high selectivity and sensitivity
Authors: Zhou Xiaojing , Guo Xiaolei , Liu Lili , Zhai Haidong , Meng Qingguo , Shi Zhan , Tai Xishi
Published: January 2020

Two luminescent 3D supramolecular structures which serve as effective luminescent sensors for Fe3+, Cu2+ and TNP via luminescent quenching have been synthesized under solvothermal conditions.
Exploring the inhibitory mechanism of piceatannol on α-glucosidase relevant to diabetes mellitus
Authors: Jiang Lili , Wang Zhen , Wang Xiaoyu , Wang Shujuan , Cao Jun , Liu Yong
Published: January 2020

The non-competitive inhibition of piceatannol on α-glucosidase. A combination of dynamic and static process with one binding site. The involvement of hydrophobic interactions and hydrogen bonding. Dietary recommendations for diabetes or potential antidiabetic drug.
Designing, docking and molecular dynamics simulation studies of novel cloperastine analogues as anti-allergic agents: homology modeling and active site prediction for the human histamine H1 receptor
Authors: Daddam Jayasimha Rayalu , Sreenivasulu Basha , Peddanna Kotha , Umamahesh Katike
Published: January 2020

The present study predicts a three-dimensional model for the histamine H1 receptor and the design of antihistamine inhibitors using cloperastine as the core molecule by docking studies.
Improved performance of dye-sensitized solar cells upon sintering of a PEDOT cathode at various temperatures
Authors: Peri Rajagopal , P Mathan Kumar , B Muthuraaman
Published: January 2020

Poly(3,4-ethylenedioxythiophene) (PEDOT) thin films have attracted considerable attention as cathodes for dye-sensitized solar cells (DSSCs) due to their air-stable, light-weight and conductive nature.
Grape skin fermentation by Lactobacillus fermentum CQPC04 has anti-oxidative effects on human embryonic kidney cells and apoptosis-promoting effects on human hepatoma cells
Authors: Liu Jia , Tan Fang , Liu Xinhong , Yi Ruokun , Zhao Xin
Published: January 2020

Studies on the antioxidant effects of grapes have attracted increasing interest.
Recent synthetic efforts in the preparation of 2-(3,4)-alkenyl (aryl) quinoline molecules towards anti-kinetoplastid agents
Authors: Orozco Dayana , Kouznetsov Vladimir V. , Bermúdez Armando , Vargas Méndez Leonor Y. , Mendoza Salgado Arturo René , Meléndez Gómez Carlos Mario
Published: January 2020

Leishmaniasis, Chagas disease and African sleeping sickness have been considered some of the most important tropical protozoan afflictions.
Correlations between the structure and the vibrational spectrum of the phosphate group. Implications for the analysis of an important functional group in phosphoproteins
Authors: Pettersson Pontus , Barth Andreas
Published: January 2020

Vibrational frequencies of phosphate are sensitive to bond length changes on the sub-picometer scale.
Self-assembly of naturally occurring stigmasterol in liquids yielding a fibrillar network and gel
Authors: Bag Braja Gopal , Barai Abir Chandan
Published: January 2020

Stigmasterol extracted from the leaves ofRoscoea purpureaspontaneously self-assembled in liquids yielding a fibrillar network and gel.
Effects of bleaching and functionalization of kaolinite on the mechanical and thermal properties of polyamide 6 nanocomposites
Authors: Raji Marya , Qaiss Abou el kacem , Bouhfid Rachid
Published: January 2020

This study presents the effects of bleaching and functionalization of kaolinite on the mechanical and thermal properties and whiteness index of polyamide 6 nanocomposites prepared by melting compounding.
A fast UV-curable PU-PAAm hydrogel with mechanical flexibility and self-adhesion for wound healing
Authors: Hou Yi , Jiang Nan , Sun Dan , Wang Yiping , Chen Xianchun , Zhu Songsong , Zhang Li
Published: January 2020

A fast UV-curable, mechanical flexible and self-adhesive PU-PAAm hydrogel has been prepared for clinical wound management.
The miscibility and spatial distribution of the components in electrospun polymer–protein mats
Authors: Pavlova Elizaveta , Nikishin Igor , Bogdanova Alexandra , Klinov Dmitry , Bagrov Dmitry
Published: January 2020

Polylactide and bovine serum albumin can be combined in a single electrospun fiber, despite the phase separation.
Apoptosis-inducing activity of a fluorescent barrel-rosette M+/Cl− channel
Authors: Malla Javid Ahmad , Umesh Rintu M. , Vijay Amal , Mukherjee Arnab , Lahiri Mayurika , Talukdar Pinaki
Published: January 2020

We report a 2-hydroxy-N1,N3-diarylisophthalamide-based self-assembled channel that cotransports M+/Cl− and induces apoptotic cell death.
Colloidal gelation, a means to study elasto-capillarity effects in foam
Authors: Mikhailovskaya Alesya , Trappe Véronique , Salonen Anniina
Published: January 2020

Impact of increasing elasto-capillarity on foam mechanics probed by gelation of colloidal particles dispersed in the foam interstices.
Ultrasound-triggered delivery of paclitaxel encapsulated in an emulsion at low acoustic pressures
Authors: Al Rifai N. , Desgranges S. , Le Guillou-Buffello D. , Giron A. , Urbach W. , Nassereddine M. , Charara J. , Contino-Pépin C. , Taulier N.
Published: January 2020

We investigated the in vitro ultrasound-triggered delivery of paclitaxel, a well known anti-cancerous drug, encapsulated in an emulsion and in the presence of CT26 tumor cells.
Coaxially enhanced photocarrier transport of a highly oriented Cu2ZnSnS4/ZnO photodetector through the nanoconfinement effect
Authors: Li Wen , Xiong Da , Xie Meilin , Luo Chao , Zeng Xiankan , Gao Yue , Guo Bolin , Yan Cheng , Chun Fengjun , Zhu Zhihao , Fan Xiaoqiang , Deng Weili , Yang Weiqing
Published: January 2020

This work demonstrates a highly c-axis-oriented Cu2ZnSnS4/ZnO (CZTS/ZnO) photodetector with coaxially enhanced photocarrier transport.
Experimental and theoretical evidence for temperature driving an electric-magnetic complementary effect in magnetic microwave absorbing materials
Authors: Yang Xuan , Duan Yuping , Zeng Yuansong , Pang Huifang , Ma Guojia , Dai Xuhao
Published: January 2020

Magnetic microwave absorbing materials (MMAMs) possess many desirable properties, including thin thickness and wide attenuation band, and thus are widely applied in many fields.
A BODIPY-based fluorescent sensor for the detection of Pt2+ and Pt drugs
Authors: Tang Fung-Kit , Zhu Jiaqian , Kong Fred Ka-Wai , Ng Maggie , Bian Qingyuan , Yam Vivian Wing-Wah , Tse Anfernee Kai-Wing , Tse Yu-Chung , Leung Ken Cham-Fai
Published: January 2020

A novel BODIPY-based fluorescent sensor PS was designed for imaging Pt2+, cisplatin and nedaplatin in aqueous medium and biological environments, providing great potential for studying the Pt-drug metabolism and the development of new platinum drugs.
Expeditious synthesis of phenanthridines through a Pd/MnO2-mediated C–H arylation/oxidative annulation cascade from aldehydes, aryl iodides and amino acids
Authors: Fan Jian , Li Li , Zhang Jitan , Xie Meihua
Published: January 2020

The expeditious access to phenanthridines through a Pd/MnO2-mediated arylation/oxidative annulation cascade from aldehydes, aryl iodides and amino acids is described.
(Z)-Selective anti-Markovnikov or Markovnikov thiol–yne-click reactions of an internal alkyne by amide hydrogen bond control
Authors: Pramanik Milan , Choudhuri Khokan , Chakraborty Subhayan , Ghosh Arindam , Mal Prasenjit
Published: January 2020

Hydrogen bonding interactions like N–H⋯S, N–H⋯N and C–H⋯O helped to obtain either (Z)-selective anti-Markovnikov or Markovnikov Thiol–Yne-Click products exclusively with excellent yields from an internal alkyne under metal free conditions.
Assembling of Bi atoms on TiO2 nanorods boosts photoelectrochemical water splitting of semiconductors
Authors: Pang Yajun , Zang Wenjie , Kou Zongkui , Zhang Lei , Xu Guangqing , Lv Jun , Gao Xiaorui , Pan Zhenghui , Wang John , Wu Yucheng
Published: January 2020

Atom-dispersed Bi metal along the TiO2 nanorods is properly designed as an efficiency co-catalyst to boost the photoelectrochemical (PEC) water splitting with a three-fold enhancement on photocurrent density.
Design and evaluation of novel thrombin-based GLP-1 analogs with peptidic albumin binding domain for the controlled release of GLP-1
Authors: Niu Xianli , Nong Shirong , Zhang Xiaomin , Li Xiangyang , Wang Cheng , Li Wei , Zhou Tianhong
Published: January 2020

Currently, the curative effects of polypeptide drugs are often restricted due to the shortin vivoduration of action.
The role of l-histidine as molecular tongs: a strategy of grasping Tb3+ using ZIF-8 to design sensors for monitoring an anthrax biomarker on-the-spot
Authors: Guo Lan , Liang Maosheng , Wang Xiuli , Kong Rongmei , Chen Guang , Xia Lian , Qu Fengli
Published: January 2020

In this study, a novel lanthanide-doped nanoprobe for monitoring dipicolinic acid (DPA), a unique biomarker of Bacillus anthracis, was constructed by coordination of Tb3+ with l-histidine (His) functionalized ZIF-8 (His@ZIF-8).
Differences in Weeklong Ambulatory Vocal Behavior Between Female Patients With Phonotraumatic Lesions and Matched Controls
Authors: Van Stan Jarrad H. , Mehta Daryush D. , Ortiz Andrew J. , Burns James A. , Toles Laura E. , Marks Katherine L. , Vangel Mark , Hron Tiffiny , Zeitels Steven , Hillman Robert E.
Published: January 2020

Purpose

Previous work using ambulatory voice recordings has shown no differences in average vocal behavior between patients with phonotraumatic vocal hyperfunction and matched controls. This study used larger groups to replicate these results and expanded the analysis to include distributional characteristics of ambulatory voice use and measures indicative of glottal closure.

Method

Subjects included 180 adult women: 90 diagnosed with vocal fold nodules or polyps and 90 age-, sex-, and occupation-matched controls with no history of voice disorders. Weeklong summary statistics (average, variability, skewness, kurtosis) of voice use were computed from neck-surface acceleration recorded using an ambulatory voice monitor. Voice measures included estimates of sound pressure level (SPL), fundamental frequency (
f
o
), cepstral peak prominence, and the difference between the first and second harmonic magnitudes (H1–H2).

Results

Statistical comparisons resulted in medium–large differences (Cohen's
d
≥ 0.5) between groups for SPL skewness,
f
o
variability, and H1–H2 variability. Two logistic regressions (theory-based and stepwise) found SPL skewness and H1–H2 variability to classify patients and controls based on their weekly voice data, with an area under the receiver operating characteristic curve of 0.85 and 0.82 on training and test sets, respectively.

Conclusion

Compared to controls, the weekly voice use of patients with phonotraumatic vocal hyperfunction reflected higher SPL tendencies (negatively skewed SPL) with more abrupt glottal closure (reduced H1–H2 variability, especially toward higher values). Further work could examine posttreatment data (e.g., after surgery and/or therapy) to determine the extent to which these differences are associated with the etiology and pathophysiology of phonotraumatic vocal fold lesions.
Carbon quantum dots modified Bi2WO6 nanoflowers for enhancing photocatalytic activity: an experimental and DFT study
Authors: Wu Kun , Song Shaojia , Wu Huadong , Guo Jia , Zhang Linfeng
Published: January 2020

Carbon quantum dots (CQDs) decorated Bi2 WO6 nanocomposites were successfully synthesised by a facile hydrothermal method. The prepared samples were characterised by the XRD, FESEM, TEM, XPS, UV–vis DRS, photocurrent and photoluminescence (PL) techniques. The DRS, photocurrent, PL spectra measurements reveal that the introduction of CQDs could broaden the absorption edge and accelerate the separation and transportation efficiency of carriers. Moreover, a reasonable charge transfer approach was given out based on the calculated work function and the differential charge difference. The CQDs/Bi2WO6‐2 sample provides the optimal activity for photodegradation of CIP under simulated sunlight irradiation. It is hopeful that this work not only gives a reference for the design of CQDs/Bi2WO6 composites, but also provides some mechanistic insights into enhanced photoactivity.
Observational constraints on the origin of the elements
Authors: Eitner P. , Bergemann M. , Hansen C. J. , Cescutti G. , Seitenzahl I. R. , Larsen S. , Plez B.
Published: January 2020

The abundance ratios of manganese to iron in late-type stars across a wide metallicity range place tight constraints on the astrophysical production sites of Fe-group elements. In this work, we investigate the chemical evolution of Mn in the Milky Way galaxy using high-resolution spectroscopic observations of stars in the Galactic disc and halo stars, as well as a sample of globular clusters. Our analysis shows that local thermodynamic equilibrium (LTE) leads to a strong imbalance in the ionisation equilibrium of Mn I and Mn II lines. Mn I produces systematically (up to 0.6 dex) lower abundances compared to the Mn II lines. Non-LTE (NLTE) radiative transfer satisfies the ionisation equilibrium across the entire metallicity range, of −3 ≲ [Fe/H] ≲ −1, leading to consistent abundances from both ionisation stages of the element. We compare the NLTE abundances with Galactic Chemical Evolution models computed using different sources of type Ia and type II supernova (SN Ia and SN II) yields. We find that a good fit to our observations can be obtained by assuming that a significant (∼75%) fraction of SNe Ia stem from a sub-Chandrasekhar (sub-Mch) channel. While this fraction is larger than that found in earlier studies (∼50%), we note that we still require ∼25% near-Mch SNe Ia to obtain solar [Mn/Fe] at [Fe/H] = 0. Our new data also suggest higher SN II Mn yields at low metallicity than typically assumed in the literature.
Humps and bumps: the effects of shocks on the optical light curves of fundamental-mode RR Lyrae stars
Authors: Prudil Z. , Dékány I. , Smolec R. , Catelan M. , Grebel E. K. , Kunder A.
Published: January 2020

We present the most extended and homogeneous study carried out so far of the main and early shocks in 1485 RR Lyrae stars in the Galactic bulge observed by the Optical Gravitational Lensing Experiment. We selected nonmodulated fundamental-mode RR Lyrae stars with good-quality photometry. Using a self-developed method, we determined the centers and strengths of main and early shock features in the phased light curves. We found that the positions of both humps and bumps are highly correlated with the pulsation properties of the studied variables. Pulsators with a pronounced main shock are concentrated in the low-amplitude regime of the period–amplitude diagram, while stars with a strong early shock have average and above-average pulsation amplitudes. A connection between the main and early shocks and the Fourier coefficients is also observed. In the color–magnitude diagram, we see a separation between stars with strong and weak shocks. Variables with a pronounced main shock cluster close to the fundamental red edge of the instability strip (IS), while stars with a strong early shock tend to clump in the center and near the fundamental blue edge of the IS. The appearance of shocks and their properties appear to be independent of the direction of evolution estimated from the period change rate of the studied stars. In addition, the differences in the period change rate between the two main Oosterhoff groups found in the Galactic bulge suggest that stars of Oosterhoff type I are located close to the zero-age horizontal branch while Oosterhoff type II variables are on their way toward the fundamental red edge of the instability strip, and have therefore already left the zero-age horizontal branch.
Apsidal motion in the massive binary HD 152248
Authors: Rosu S. , Rauw G. , Conroy K. E. , Gosset E. , Manfroid J. , Royer P.
Published: January 2020

Context. The eccentric massive binary HD 152248 (also known as V1007 Sco), which hosts two O7.5 III-II(f) stars, is the most emblematic eclipsing O-star binary in the very young and rich open cluster NGC 6231. Its properties render the system an interesting target for studying tidally induced apsidal motion.

Aims. Measuring the rate of apsidal motion in such a binary system gives insight into the internal structure and evolutionary state of the stars composing it.

Methods. A large set of optical spectra was used to reconstruct the spectra of the individual binary components and establish their radial velocities using a disentangling code. Radial velocities measured over seven decades were used to establish the rate of apsidal motion. We furthermore analysed the reconstructed spectra with the CMFGEN model atmosphere code to determine stellar and wind properties of the system. Optical photometry was analysed with the Nightfall binary star code. A complete photometric and radial velocity model was constructed in PHOEBE 2 to determine robust uncertainties.

Results. We find a rate of apsidal motion of (1.843−0.083+0.064)° yr−1. The photometric data indicate an orbital inclination of (67.6−0.1+0.2)° and Roche-lobe filling factors of both stars of about 0.86. Absolute masses of 29.5−0.4+0.5 M⊙ and mean stellar radii of 15.07−0.12+0.08 R⊙ are derived for both stars. We infer an observational value for the internal structure constant of both stars of 0.0010 ± 0.0001.

Conclusions. Our in-depth analysis of the massive binary HD 152248 and the redetermination of its fundamental parameters can serve as a basis for the construction of stellar evolution models to determine theoretical rates of apsidal motion to be compared with the observational one. In addition, the system hosts two twin stars, which offers a unique opportunity to obtain direct insight into the internal structure of the stars.
Le chaos de l’éveil de coma comme organisateur du psychisme
Authors: Minjard Raphaël
Published: January 2020

Cet article propose d’explorer, dans une perspective psychanalytique, la confusion ou le délire vécus par les patients à l’éveil de coma.

Cette confusion est abordée sous l’angle du constat clinique de la désorganisation du sujet, associée au contexte de la réanimation et au vécu traumatique antérieur. Le délire est ensuite exploré comme représentant des potentialités réorganisatrices témoignant d’un processus intrasubjectif et intersubjectif à l’œuvre.
Coordination for pull and push contracts in decentralized system with uncertain supply
Authors: Zhang Wensi , Chu Hongrui
Published: January 2020

This paper investigates how a random supply can influence management decisions under pull and push contracts in a decentralized supply chain with one supplier and one retailer. We suppose that the supplier faces yield uncertainty, and we adopt game models to analyse the supply chain members’ decisions (i.e., wholesale price and order quantity) under the two commonly used contracts. Specifically, we analyse the revenue sharing mechanism and buyback mechanism with pull and push contracts, respectively, and find that the buyback contract can efficiently coordinate the supply chain with push contract, while the revenue sharing contract cannot improve the performance with a pull contract. Then we design a modified revenue sharing contract that introduces a subsidy for excess inventory and shows that for the pull case, the proposed mechanism can coordinate the supply chain effectively. Finally, the analysis results are displayed intuitively by numerical cases.
In Vitro and In Vivo Activity of Anogeissus leiocarpa Bark Extract and Isolated Metabolites against Toxoplasma gondii
Authors: Spalenka Jérémy , Hubert Jane , Voutquenne-Nazabadioko Laurence , Escotte-Binet Sandie , Borie Nicolas , Velard Frédéric , Villena Isabelle , Aubert Dominique , Renault Jean-Hugues
Published: January 2020

Toxoplasma gondii, belonging to the Apicomplexa phylum, is a cosmopolitan protozoan parasite that affects at least 30% of the worldʼs population. In West Africa, the leaves and bark of the tree species Anogeissus leiocarpa (DC.) Guill. & Perr. are used against zoonosis in traditional medicine and play a key role in controlling diseases induced by Apicomplexans such as malaria. In this study, extracts, fractions, and pure compounds obtained from an ethanol extract of the bark of A. leiocarpa were evaluated against T. gondii infection in vitro and in vivo. The crude bark extract showed significant activity on tachyzoites from the T. gondii RH strain (IC50 = 59.30 µg/mL). The crude bark extract without tannins and pure trachelosperogenin E purified by centrifugal partition chromatography showed the highest activity (IC50s = 12.83 and 26.63 µg/mL, respectively) with satisfying selectivity indexes of 9.61 and 9.75, respectively. The crude bark extract without tannins and pure trachelosperogenin E were able to significantly inhibit host cell invasion by the parasite in vitro, while the crude bark extract without tannins was able to increase mice survival in our murine model of chronic toxoplasmosis. These results provide new biological data for natural compounds that could enhance the current panoply of treatments against toxoplasmosis.
Iodobenzene-Catalyzed Oxidative Cyclization for the Synthesis of Highly Functionalized Cyclopropanes
Authors: Li Yang , Guo Hao , Fan Renhua
Published: January 2020

An iodobenzene-catalyzed oxidative cyclization of Michael adducts of activated methylene compounds with nitroolefins or chalcones is developed. mCPBA is used as oxidant together with Bu4NI for the generation of a highly reactive iodine(III) species to mediate the cyclopropanation via a ligand exchange and reductive elimination process. A range of highly functionalized cyclopropanes are synthesized with high diastereoselectivities.
Evaluating Usability of a Touchless Image Viewer in the Operating Room
Authors: Bockhacker Markus , Syrek Hannah , Elstermann von Elster Max , Schmitt Sebastian , Roehl Henning
Published: January 2020

Background Availability of patient-specific image data, gathered from preoperatively conducted studies, like computed tomography scans and magnetic resonance imaging studies, during a surgical procedure is a key factor for surgical success and patient safety. Several alternative input methods, including recognition of hand gestures, have been proposed for surgeons to interact with medical image viewers during an operation. Previous studies pointed out the need for usability evaluation of these systems.

Objectives We describe the accuracy and usability of a novel software system, which integrates gesture recognition via machine learning into an established image viewer.

Methods This pilot study is a prospective, observational trial, which asked surgeons to interact with software to perform two standardized tasks in a sterile environment, modeled closely to a real-life situation in an operating room. To assess usability, the validated “System Usability Scale” (SUS) was used. On a technical level, we also evaluated the accuracy of the underlying neural network.

Results The neural network reached 98.94% accuracy while predicting the gestures during validation. Eight surgeons with an average of 6.5 years of experience participated in the usability study. The system was rated on average with 80.25 points on the SUS.

Conclusion The system showed good overall usability; however, additional areas of potential improvement were identified and further usability studies are needed. Because the system uses standard PC hardware, it made for easy integration into the operating room.
ALG-9 Congenital Disorder of Glycosylation: A Patient with Novel Variants and No Dysmorphism
Authors: Goswami Jyotindra Narayan , Roy Shuvendu
Published: January 2020

We report a child with ALG-9 congenital disorder of glycosylation (ALG9-CDG) with two novel missense variants on clinical exome sequencing. Unlike the 11 previously reported patients, index child did not have dysmorphism. The case portrays the clinical heterogeneity of ALG-9 CDG.
Acute Vestibular Syndrome
Authors: Kerber Kevin A.
Published: January 2020

The acute vestibular syndrome (AVS) is a label for presentations of new-onset severe dizziness, vertigo, or imbalance, with examination findings of nystagmus or gait unsteadiness. The prototypical AVS presentation is the acute unilateral vestibulopathy due to vestibular neuritis. Stroke is also a serious concern in patients with AVS. Most other peripheral vestibular disorders present as episodic or chronic syndromes. In this article, the diagnostic considerations, exam findings, and management of AVS are reviewed.
Treatment of Vascular Thrombosis in Antiphospholipid Syndrome: An Update
Authors: Kalmanti Lida , Lindhoff-Last Edelgard
Published: January 2020

The antiphospholipid syndrome (APS) is an acquired autoimmune disorder associated with arterial, venous, or microvascular thrombosis and/or pregnancy complications mainly in young age. The diagnosis is made by the persistent detection of anticardiolipin antibodies, β2-glycoprotein I antibodies (β2GPIA), and/or lupus anticoagulants (LAs) for at least 12 weeks. Patients should present with at least one clinical and one laboratory criterion. Patients presenting with all three types of antibodies and vascular events are high-risk patients and should receive vitamin K antagonists (VKAs) as long as the antibodies persist. In patients with prior arterial thrombosis, VKA with or without low-dose aspirin is the current treatment of choice. The international normalized ratio (INR) should be between 2 and 3 although in some cases keeping the target INR above 3 may be necessary. Patients with venous thrombosis and negative LA may alternatively be treated with direct oral anticoagulants although more data are needed. Minimizing vascular risk factors is always necessary in APS patients. Aspirin can be given as primary prevention in asymptomatic patients with positive antiphospholipid antibodies without thrombosis or pregnancy complications especially when additional vascular risk factors are present. Catastrophic APS occurs in less than 1% of APS patients and presents as a thrombotic storm. Early use of a combined triple therapy such as anticoagulation, plasma exchange, and steroids with either or not addition of immunoglobulins is important to reduce mortality.
Advances in Understanding Mechanisms of Thrombophilic Disorders
Authors: Dahlbäck Björn
Published: January 2020

Venous thromboembolism constitutes a major medical problem afflicting millions of individuals worldwide each year. Its pathogenesis is multifactorial, involving both environmental and genetic risk factors. The most common genetic risk factor known to date is a mutation in the factor V (FV) gene (R506Q or FV Leiden), which impairs the normal regulation of FV by activated protein C (APC). APC is an important regulator of blood coagulation, cleaving and inactivating not only FV/FVa but also activated factor VIII (FVIIIa). In FVa, APC cleaves several sites, Arg506 (R506) being one of them. The R506Q mutation results in the APC resistance phenotype and a lifelong hypercoagulable state. A prothrombin gene mutation is another relatively frequent thrombosis risk factor, whereas deficiencies of the anticoagulant proteins antithrombin, protein C, or protein S are less common. As a result of the high prevalence of FV and prothrombin mutations in the general population, combinations of genetic defects are relatively common. Such individuals have highly increased risk of thrombosis.
Learning with Concept Maps versus Learning with Classical Lecture and Demonstration Methods in Neuroanatomy - A Comparison
Authors: Anand Mahindra Kumar , Singh Olive , Chhabra Prabhjot Kaur
Published: January 2020

Aims and Objectives: Concept maps as learning tool facilitate development of meaningful learning. It was developed by Novak and Gowin and is based on Ausubel's theory of meaningful learning. Present study was undertaken to sensitize students to use concept maps as a learning tool and to assess its effect on learning. The objectives of the study were to compare the learning with concept maps and traditional lecture-demonstration methods in neuroanatomy. Materials and Methods: A randomized cross sectional prospective study was conducted on 60 medical students of 1st year. Students were divided into 3 groups A, В and C. Group A studied “spinal cord and its meninges” by developing concept maps. Group C learnt through lecture and demonstration method. Group В studied with readymade concept maps, lecture and demonstration methods. Pre and post test were conducted for all groups with pre validated questionnaire. Feedback was obtained from both students and faculty through a 5 point Likert scale. Paired and unpaired t test were applied for statistical analysis. Results: There was significant improvement in knowledge in group A students in comparison to group C and В students. This improvement was more marked with regards to high cognitive type MCQs. 80% students found that development of concept maps helped them to understand topic better but it was time consuming. Conclusion: Concept mapping is a better learning tool in comparison to classical lecture and demonstration method. It facilitates higher cognitive learning. It can be included in medical undergraduate curriculum to facilitate meaningful learning.
Experimental investigation of electrohydrodynamic modes in electrospraying of viscoelastic polymeric solutions
Authors: Panahi Amirreza , Pishevar Ahmad Reza , Tavakoli Mohammad Reza
Published: January 2020

The main aim of this study is to explore the role of viscoelastic properties of polymeric solutions on mode transitions in the electrospray process. By adjusting the applied electric potential between the nozzle and the collecting substrate, various electrohydrodynamic (EHD) modes were photographed by using a high-speed camera. Then, the effect of operating parameters on the droplet size in the dripping mode and the jet profile in the jet mode was investigated. By categorizing the EHD modes of each viscoelastic solution into dimensionless operating maps, it can be seen that by increasing the solution concentration, the extents of dripping mode and beads-on-a-string structure dwindle, while the jet stabilizes in a wider range of electric capillary numbers. Furthermore, contrary to deionized water, when the applied voltage escalates, the stick jet mode is observed where the jet sticks to the outer surface of the nozzle and the asymptotic thickness of the jet falls.
Nonlinear correlations in multifractals: Visibility graphs of magnitude and sign series
Authors: Manshour Pouya
Published: January 2020

Correlations in a multifractal series have been investigated extensively. Almost all approaches try to find scaling features of a given time series. However, the scaling analysis has always been encountered with some difficulties. Of particular importance is finding a proper scaling region and removing the impact of the probability distribution function of the series on the correlation extraction methods. In this article, we apply the horizontal visibility graph algorithm to map a stochastic time series into networks. By investigating the magnitude and sign of a multifractal time series, we show that one can detect linear as well as nonlinear correlations, even for situations that have been considered as uncorrelated noises by typical approaches such as the multifractal detrended fluctuation analysis. Furthermore, we introduce a topological parameter that can well measure the strength of nonlinear correlations. This parameter is independent of the probability distribution function and calculated without the need to find any scaling region. Our findings may provide new insights about the multifractal analysis of a time series in a variety of complex systems.
A comparative first-principles investigation on the defect chemistry of TiO2 anatase
Authors: Arrigoni Marco , Madsen Georg K. H.
Published: January 2020

Understanding native point defects is fundamental in order to comprehend the properties of TiO2 anatase in technological applications. The previous first-principles reports of defect-relevant quantities, such as formation energies and charge transition levels, are, however, scattered over a wide range. We perform a comparative study employing different approaches based on semilocal with Hubbard correction (DFT+U) and screened hybrid functionals in order to investigate the dependence defect properties on the employed computational method. While the defects in TiO2 anatase, as in most transition-metal oxides, generally induce the localization of electrons or holes on atomic sites, we notice that, provided an alignment of the valence bands has been performed, the calculated defect formation energies and transition levels using semilocal functionals are in a fair agreement with those obtained using hybrid functionals. A similar conclusion can be reached for the thermochemistry of the Ti–O system and the limit values of the elemental chemical potentials. We interpret this as a cancellation of error between the self-interaction error and the overbinding of the O2 molecule in semilocal functionals. Inclusion of a U term in the electron Hamiltonian offers a convenient way for obtaining more precise geometric and electronic configurations of the defective systems.
Australian Rainforest Seeds
Authors: Dunphy Mark , McAlpin Steve , Nelson Paul , Chapman Michelle , Nicholson Hugh
Published: January 2020

Have you ever wondered how to grow your own rainforest trees? Is there a beautiful tree that you have always wanted to collect and propagate the seed from? Are you in the business of ecological restoration, rainforest propagation or environmental education?
This long-awaited guide to rainforest seed propagation unlocks the secrets to growing 300 rainforest species. Providing specific information on how to sustainably collect, process and germinate seeds, this user-friendly book aims to support a growing movement of rainforest restoration.
With invaluable information based on 30 years of research in northern New South Wales, users will find even difficult rainforest species delightfully easy to grow. Seeing a seed germinate, caring for the seedling and eventually planting the tree is deeply satisfying. And, in this time of widespread deforestation, millions of trees are needed for restoration and every tree counts. Whether you are growing one or one hundred thousand, why not start today?
Asynchrony between the early embryo and the reproductive tract affects subsequent embryo development in cattle
Authors: Rodríguez-Alonso Beatriz , Sánchez José María , Hamdi Meriem , McDonald Michael , Havlicek Vitezslav , Besenfelder Urban , Lonergan Patrick , Rizos Dimitrios
Published: January 2020

The aim of this study was to determine the effect of maternal–embryonic asynchrony in the reproductive tract (oviduct and uterus) on subsequent embryo development in cattle. Fifty Day 1invitro-produced zygotes were transferred endoscopically into the oviduct ipsilateral to the corpus luteum of heifers (n=40) that were either synchronous with the embryos (Day 1 after ovulation) or asynchronous and ahead of the embryo (Day 3 after ovulation). A subset of heifers was killed in a commercial abattoir 3, 6 or 14 days after embryo transfer. Location within the reproductive tract, developmental stage and the quality of embryos were recorded. Transfer of embryos to an advanced (asynchronous) oviduct resulted, on Day 4, in fewer embryos at the expected location (oviduct), and a greater number of degenerated and retarded embryos with a lower total cell number than for embryos in the synchronous group. Similarly, on Day 7, asynchrony led to a greater number of degenerated and retarded embryos compared with the synchronous group. Total embryo cell number was similar among groups. Although Day 15 conceptuses were longer following asynchronous transfer, only 50% of the asynchronous heifers yielded conceptuses, compared with 100% in the synchronous group. In conclusion, asynchrony between the developing embryo and the reproductive tract has a negative effect on embryo development.
A theoretical framework for comparing noise characteristics of spectral, differential phase-contrast and spectral differential phase-contrast x-ray imaging
Authors: Mechlem Korbinian , Sellerer Thorsten , Viermetz Manuel , Herzen Julia , Pfeiffer Franz
Published: January 2020

Spectral and grating-based differential phase-contrast (DPC) x-ray imaging are two emerging technologies that offer additional information compared with conventional attenuation-based x-ray imaging. In the case of spectral imaging, energy-resolved measurements allow the generation of material-specific images by exploiting differences in the energy-dependent attenuation. DPC imaging uses the phase shift that an x-ray wave exhibits when traversing an object as contrast generation mechanism. Recently, we have investigated the combination of these two imaging techniques (spectral DPC imaging) and demonstrated potential advantages compared with spectral imaging. In this work, we present a noise analysis framework that allows the prediction of (co-) variances and noise power spectra for all three imaging methods. Moreover, the optimum acquisition parameters for a particular imaging task can be determined. We use this framework for a performance comparison of all three imaging methods. The comparison is focused on (projected) electron density images since they can be calculated with all three imaging methods. Our study shows that spectral DPC imaging enables the calculation of electron density images with strongly reduced noise levels compared with the other two imaging methods for a large range of clinically relevant pixel sizes. In contrast to conventional DPC imaging, there are no long-range noise correlations for spectral DPC imaging. This means that excessive low frequency noise can be avoided. We confirm the analytical predictions by numerical simulations.
Calculated beam quality correction factors for ionization chambers in MV photon beams
Authors: Tikkanen J , Zink K , Pimpinella M , Teles P , Borbinha J , Ojala J , Siiskonen T , Gomà C , Pinto M
Published: January 2020

The beam quality correction factor,

, which corrects for the difference in the ionization chamber response between the reference and clinical beam quality, is an integral part of radiation therapy dosimetry. The uncertainty of

is one of the most significant sources of uncertainty in the dose determination. To improve the accuracy of available

data, four partners calculated

factors for 10 ionization chamber models in linear accelerator beams with accelerator voltages ranging from 6 MV to 25 MV, including flattening-filter-free (FFF) beams. The software used in the calculations were EGSnrc and PENELOPE, and the ICRU report 90 cross section data for water and graphite were included in the simulations. Volume averaging correction factors were calculated to correct for the dose averaging in the chamber cavities. A comparison calculation between partners showed a good agreement, as did comparison with literature. The

values from TRS-398 were higher than our values for each chamber where data was available. The

values for the FFF beams did not follow the same

,

relation as beams with flattening filter (values for 10 MV FFF beams were below fits made to other data on average by 0.3%), although our FFF sources were only for Varian linacs.
Combat operations of the German armed forces on the Northern sea route during the Great Patriotic War
Authors: Guriev E P
Published: January 2020

The paper is devoted to the combat actions of the German navy and aviation in the Arctic during the Great Patriotic War of 1941-1945 on the Northern sea route. The Northern sea route is the most important sea communication of Russia in the Arctic. It connects the European part of the country with the Far East by the shortest route, and therefore has a special strategic importance for the cargo shipping logistics. This route passes through the seas of the Arctic Ocean and, despite the complexity of navigation in the Arctic seas, is the only communication that provides supply to the Polar Regions and cities of Siberia in the absence of railways and roads. No less important is its military and strategic importance, as the Northern sea route allows for inter-theater maneuver between the Northern and Pacific fleets. At the same time, due to its vast length and uninhabitability of the nearby territories, the Northern sea route is very vulnerable militarily, which can be used by a potential enemy of Russia in case of international relations aggravation in the Arctic, the violation of this route inflicts a heavy blow to the logistics of Maritime transport in the North. The main attention is paid to the creation by the Germans of military bases and weather stations network in the Soviet sector of the Arctic, to the organization and composition of these bases. The paper also analyzed the organization of the meteorological service of the German Navy operation “Wunderland” (“Wonderland”) and mine-laying off at the coast of New Land, the causes of the German fleet failure on the Northern sea route.