bluuebunny/crossref_metadata_2025 huggingface dataset:
Receptor modulators associated with the hypothalamus -pituitary-thyroid axis
Authors: Cheng Xianbin , Zhang Hong , Guan Shanshan , Zhao Qi , Shan Yaming
Published: December 2023

The hypothalamus-pituitary-thyroid (HPT) axis maintains normal metabolic balance and homeostasis in the human body through positive and negative feedback regulation. Its main regulatory mode is the secretion of thyrotropin (TSH), thyroid hormones (TH), and thyrotropin-releasing hormone (TRH). By binding to their corresponding receptors, they are involved in the development and progression of several systemic diseases, including digestive, cardiovascular, and central nervous system diseases. The HPT axis-related receptors include thyrotropin receptor (TSHR), thyroid hormone receptor (TR), and thyrotropin-releasing hormone receptor (TRHR). Recently, research on regulators has become popular in the field of biology. Several HPT axis-related receptor modulators have been used for clinical treatment. This study reviews the developments and recent findings on HPT axis-related receptor modulators. This will provide a theoretical basis for the development and utilisation of new modulators of the HPT axis receptors.
An enhanced respiratory mechanics model based on double-exponential and fractional calculus
Authors: Li Zongwei , Pei Yanbin , Wang Yuqi , Tian Qing
Published: December 2023

We address mathematical modelling of respiratory mechanics and put forward a model based on double-exponential and fractional calculus for parameter estimation, model simulation, and evaluation based on actual data. Our model has been implemented on a publicly available executable code with adjustable parameters, making it suitable for different applications. Our analysis represents the first application of fractional calculus and double-exponential modelling to respiratory mechanics, and allows us to propose a hybrid model fitting experimental data in different ventilation modes. Furthermore, our model can be used to study the mechanical features of the respiratory system, improve the safety of ventilation techniques, reduce ventilation damages, and provide strong support for fast and adaptive determination of ventilation parameters.
Genome-wide association analysis of plant architecture traits using doubled haploid lines derived from different cycles of the Iowa Stiff Stalk Synthetic maize population
Authors: Ledesma Alejandro , Santana Alice Silva , Sales Ribeiro Fernando Augusto , Aguilar Fernando S. , Edwards Jode , Frei Ursula , Lübberstedt Thomas
Published: December 2023

Selection in the Iowa Stiff Stalk Synthetic (BSSS) maize population for high yield, grain moisture, and root and stalk lodging has indirectly modified plant architecture traits that are important for adaptation to high plant density. In this study, we developed doubled haploid (DH) lines from the BSSS maize population in the earliest cycle of recurrent selection (BSSS), cycle 17 of reciprocal recurrent selection, [BSSS(R)17] and the cross between the two cycles [BSSS/BSSS(R)C17]. We aimed to determine the phenotypic variation and changes in agronomic traits that have occurred through the recurrent selection program in this population and to identify genes or regions in the genome associated with the plant architecture changes observed in the different cycles of selection. We conducted a per se evaluation of DH lines focusing on high heritability traits important for adaptation to high planting density and grain yield. Trends for reducing flowering time, anthesis-silking interval, ear height, and the number of primary tassel branches in BSSS(R)17 DH lines compared to BSSS and BSSS/BSSS(R)C17 DH lines were observed. Additionally, the BSSS(R)C17 DH lines showed more upright flag leaf angles. Using the entire panel of DH lines increased the number of SNP markers identified within candidate genes associated with plant architecture traits. The genomic regions identified for plant architecture traits in this study may help to elucidate the genetic basis of these traits and facilitate future work about marker-assisted selection or map-based cloning in maize breeding programs.
Archetypes of youth as vectors in power relations - From praises to information operations
Authors: Meriläinen Niina , Hiljanen Mikko , Rautiainen Matti
Published: December 2023

The purpose of this explorative and mixed methods research is to discover and describe the possible archetypes of high school and vocational school students from empirical data produced by young people and media, and to discuss what kinds of power relations these archetypes can create in Finnish society. Indeed, the empirical data produced by young people and those found in newspapers reveal archetypes and various power relations. In particular, the data indicate how the vectors of such archetypes guide thinking about young people and their life courses. In particular, the archetypes illustrate how vocational school students have to defend themselves and their choices in their daily lives, while high school students do not. Furthermore, the empirical data illustrate how the lives of vocational school students are mainly described as happening here and toward the future of the voiceless proletariat, while high school students are considered active and successful changemakers. Vocational school students also question official Finland and the place where they have been situated. Among others, this can create an opportunity for information operations.
The socio-psychological factors affecting the voting behaviour of the postgraduate politics students: a Q-methodology study
Authors: Şener Turan , Balku Yaşam , Alkan Yavuz Selim , Doru Serkan , Okudan Dernek Kadriye , Zenginoğlu Samet
Published: December 2023

This study aims to answer the question “Are voting behaviours of postgraduate students, a voter group who are politically educated and well-informed about voting behaviours, affected by socio-psychological factors?.” In particular, if so, it also aims to reveal which socio-psychological factors affect their voting behaviours. The Q-methodology is utilised in this study. The main reason for this methodological preference is that the Q-methodology is a good tool for systematically identifying and examining a particular group’s subjective views that are held around the factors shaping and affecting their voting behaviours by providing factor loadings. Factor loadings, or the cluster of participants, allow us better to illustrate each participant’s association with each of the identified socio-psychological or otherwise factors, similar or different orders of ranking by the participants, to detect individual differences, and, therefore, to indicate (1) whether the socio-psychological factors affect the voting behaviours of the participants, and (2) if so, which socio-psychological factor(s) affects most. This also helps us to conclude that the participants who are mostly associated with one or more factors have similar voting behaviours corresponding to or in opposition to the assumptions of the socio-psychological approach. The participants of the research are 57 postgraduate students studying Political Science and Public Administration at Akdeniz University. The results of the research indicate that most of the participants cluster around two separate factors: while the participants gathered under Factor 1 take their political decisions more rationally and are ready to vote for alternative candidates and political parties in different elections, those who load under Factor 2 are affected by some socio-psychological factors: loyalty to her family’s (the family factor) and inner circles’ political preferences (the inner circle factor), and a long-term commitment and an emotional attachment to a political party and/or the candidate (the time factor). The voting behaviours of the participants gathered under no factors are, however, affected by relatively mixed factors. In addition, it is also revealed that the titles that most differentiate the preferences of the participants cluster around both Factors 1 and 2 are family, education, and rationality.
A social science research agenda to accelerate public engagement in climate change adaptation
Authors: Harcourt Rachel , Dessai Suraje , Bruine de Bruin Wandi , Taylor Andrea
Published: December 2023

Recent studies find that people in high-income countries now think of climate change impacts, such as flooding or periods of high temperature, as being of immediate relevance and concern. Individuals and households can take adaptation actions to help limit the severity of harm caused when climate impacts occur, for example, they could make adjustments to their homes such as installing flood gates or sun shades, or they could adapt their behavior such as staying indoors during the hottest part of the day. However, so far adaptation is not yet happening at the speed or scale needed to adequately prepare for the climate impacts already being experienced or those projected for the coming decades. Here, we propose an agenda for future social science research that would further our understanding of how best to increase engagement and action in climate change adaptation.
Understanding COVID-19 vaccine hesitancy in vasculitis patients
Authors: Butt Imama N. , van Eeden Charmaine , Kovacs Burns Katharina , Saxinger Lynora , Clifford Alison , Redmond Desiree , Cohen Tervaert Jan Willem , Yacyshyn Elaine
Published: December 2023

Objective

To identify the factors that impact COVID-19 vaccine decision-making in vaccine-hesitant vasculitis patients, and compare their perceptions with other rheumatology patients, given existence of data suggesting rheumatology patients may have disease-specific factors that influence their COVID-19 vaccine decision-making.

Methods

This cross-sectional study surveyed adult rheumatology patients from the Kaye Edmonton Clinic Rheumatology Clinic, in Canada, between June and August 2021, using an anonymous online questionnaire. Survey responses were analyzed for statistical differences using chi-square analysis.

Results

The COVID-19 Vaccine Perceptions Survey had a response rate of 70.9%. Of the total 231 respondents, 103 patients were diagnosed with vasculitis. At the time of the survey, 10.6% of vasculitis patients refused to receive a COVID-19 vaccine compared to 6.3% for other rheumatology patients. Compared to other rheumatology patients, vaccine-hesitant vasculitis patients were significantly more concerned about almost every aspect of available COVID-19 vaccines [e.g., safety (p < 0.001), components (p < 0.001)], and feared that they could contract SARS-CoV-2 from a vaccine (p < 0.001). These vaccine-hesitant patients were also significantly less pleased with the government's pandemic response, less confident in healthcare team-provided information (p < 0.001), and more likely to report that healthcare providers had no role in their COVID-19 vaccine decision-making (p < 0.001).

Conclusion

Vaccine-hesitant vasculitis patients may have multiple considerations influencing COVID-19 vaccine hesitancy, including vaccine and disease-specific concerns, along with unfavorable perceptions of the healthcare system (government and healthcare providers). Healthcare providers can address some of these concerns by initiating patient-centered discussions around immunizations to help support educated decision-making.
Examining provider perceptions and practices for comprehensive geriatric assessment among cancer survivors: a qualitative study with an implementation science focus
Authors: Seaman Aaron T. , Rowland Julia H. , Werts Samantha J. , Tam Rowena M. , Torres Tara K. , Hucek Freda Allyson , Wickersham Karen E. , Fairman Ciaran M. , Patel Hiten D. , Thomson Cynthia A. , Hebert James R. , Friedman Daniela B.
Published: December 2023

Introduction: Cancer rates increase with age, and older cancer survivors have unique medical care needs, making assessment of health status and identification of appropriate supportive resources key to delivery of optimal cancer care. Comprehensive geriatric assessments (CGAs) help determine an older person’s functional capabilities as cancer care providers plan treatment and follow-up care. Despite its proven utility, research on implementation of CGA is lacking.

Methods: Guided by a qualitative description approach and through interviews with primary care providers and oncologists, our goal was to better understand barriers and facilitators of CGA use and identify training and support needs for implementation. Participants were identified through Cancer Prevention and Control Research Network partner listservs and a national cancer and aging organization. Potential interviewees, contacted via email, were provided with a description of the study purpose. Eight semi-structured interviews were conducted via Zoom, recorded, and transcribed verbatim by a professional transcription service. The interview guide explored providers’ knowledge and use of CGAs. For codebook development, three representative transcripts were independently reviewed and coded by four team members. The interpretive process involved reflecting, transcribing, coding, and searching for and identifying themes.

Results: Providers shared that, while it would be ideal to administer CGAs with all new patients, they were not always able to do this. Instead, they used brief screening tools or portions of CGAs, or both. There was variability in how CGA domains were assessed; however, all considered CGAs useful and they communicated with patients about their benefits. Identified facilitators of implementation included having clinic champions, an interdisciplinary care team to assist with implementation and referrals for intervention, and institutional resources and buy-in. Barriers noted included limited staff capacity and competing demands on time, provider inexperience, and misaligned institutional priorities.

Discussion: Findings can guide solutions for improving the broader and more systematic use of CGAs in the care of older cancer patients. Uptake of processes like CGA to better identify those at risk of poor outcomes and intervening early to modify treatments are critical to maximize the health of the growing population of older cancer survivors living through and beyond their disease.
Causality: Using Math to Understand the Science of Cause and Effect
Authors: Emmert-Streib Frank , Dehmer Matthias
Published: December 2023

Some people say mathematics is the most important subject in science because it is the language of nature. In this article, we provide examples for this by explaining causality. Causality is an important concept because it influences essentially all areas of science and society. In simple terms, causality is the principle that examines the link between a “cause” and an “effect”. This allows us to study important practical questions. For instance, in medicine, biology or law, one can ask “What medication can be used to treat this disease?” “What protein activates a certain gene?” or “What criminal act caused the harm?” To answer these and similar questions, methods from probability, statistics, and graph theory are needed to quantify the meaning of causality. In this article, we provide an overview of this fascinating topic.
Effect of Wu Zhi San supplementation in LPS-induced intestinal inflammation and barrier damage in broilers
Authors: Sun Han , Zheng Xirui , Yang Bowen , Yan Mingen , Wang Huiting , Yang Shijing , Shi Dayou , Guo Shining , Liu Cui
Published: December 2023

Intestinal inflammation and barrier damage can inhibit the absorption and transportation of nutrients in the small intestine, and lead to various chronic diseases. Wu Zhi San (WZS) is a traditional Chinese formula composed of Schisandrae, Anemarrhenae, Lonicerae, and Glycyrrhizae that was made to cure intestinal inflammation and barrier damage in broilers. To evaluate the protective effect of WZS on intestinal inflammation and barrier damage of broilers under lipopolysaccharide (LPS) stress, a total of 200 one-day-old broilers were randomly divided into five groups, namely, the CON group, LPS group, and three WZS groups (WZS-H, WZS-M, and WZS-L). The groups were designed for stress phase I (days 15, 17, 19, and 21) and stress phase II (days 29, 31, 33, and 35). The protective effect of WZS on the intestinal tract was evaluated by measuring the levels of serum myeloperoxidase (MPO), diamine oxidase (DAO), super oxide dismutase (SOD), and serum D-lactate (D-LA) and the expression of inflammatory factors in jejunum. The results showed that the diet supplemented with WZS could significantly reduce serum MPO, DAO, and D-LA levels and jejunal CD in broilers (p < 0.05), increase serum SOD levels and jejunal VH (p < 0.05), significantly downregulate the expression of NF-κB, TLR4, MyD88, and inflammatory cytokines (TNF-α, IL-1β, IL-6, and IL-10), and upregulate Claudin-1, Occludin-1, and ZO-1 in broiler jejunum mucosa (p < 0.05). On the other hand, WZS could significantly reduce the protein expression of NF-κB (p65) in broiler jejunum (p < 0.05). These results indicate that supplementing WZS in the diet can reduce intestinal inflammation and alleviate intestinal barrier damage, and by inhibiting the NF-κB/TLR4/MyD88 signaling pathway, supplementation with WZS intervenes in LPS-induced stress injury in broilers.
Intramuscular vitamin A injection in newborn lambs enhances antioxidant capacity and improves meat quality
Authors: Song Pengkang , Huo Guoqiang , Feng Jinxin , Zhang Weipeng , Li Xuying , Zhao Junxing
Published: December 2023

Introduction

Vitamin A (VA) and its metabolite, retinoic acid (RA) possess several biological functions. This report investigated whether neonatal intramuscular VA injection affected antioxidative activity and meat quality in longissimus dorsi (LD) muscle of lambs.

Methods

Lambs were injected with 0 (control) or 7,500 IU VA palmitate into the biceps femoris muscle on day 2 after birth. At 3, 12, and 32 weeks of age, blood samples were collected in the jugular vein for serum levels of RA and muscle samples were collected in the biceps femoris for analysis of relative mRNA expression of enzyme contributors to retinoid metabolism. All animals were harvested at 32 weeks of age and muscle samples were collected to explore the role of VA on the meat quality and antioxidant capacity of lambs.

Results and discussion

Our results indicated that VA increased the redness, crude protein, and crude fat (p < 0.05), without affecting moisture, ash, and amino acid composition in LD muscle (p > 0.05). In addition, VA increased catalase (CAT) activity and decreased malondialdehyde (MDA) levels in LD muscle (p < 0.05). Meanwhile, greater levels of CAT and NRF2 mRNA and protein contents with VA treatment were observed in LD muscle (p < 0.05), partly explained by the increased level of RA (p < 0.05). Collectively, our findings indicated that VA injection at birth could improve lamb meat quality by elevating the redness, crude protein, crude fat, and antioxidative capacity in LD muscle of lambs.
Effects of Lentilactobacillus buchneri and chemical additives on fermentation profile, chemical composition, and nutrient digestibility of high-moisture corn silage
Authors: Wang Lei , Bao Jinze , Zhuo Xingliang , Li Yingqi , Zhan Wenyuan , Xie Yixiao , Wu Zhe , Yu Zhu
Published: December 2023

High-moisture corn silage presents a novel approach to reduce forage feeding expenses and enhance animal performance. Nevertheless, given corn’s proclivity for starch, suboptimal fermentation quality in high-moisture corn silage can lead to spoilage, posing risks to livestock well-being. Therefore, the objective of this study is to evaluate the effects of different additives on the fermentation profile, chemical composition, nutrient digestibility of high-moisture corn (HMC) silage. All treatments improved the quality of high-moisture corn silage fermentation, as demonstrated by a decrease in pH and increase in lactic acid (LA) content. The high-moisture corn silage had a low content of trans fatty acids (TFA). Fermentation effectively decreased prolamin content while increasing 48-h in vitro dry matter digestibility (IVDMD), estimated total tract starch digestibility (eTTSD), total digestible nutrient (TDN), and relative grain quality (RGQ) of high-moisture corn silage. Nonetheless, no effect was observed on the 48-h IVDMD of high-moisture corn silage among the different treatments. Pearson’s correlation analysis indicated that neutral detergent fiber (aNDF), neutral detergent insoluble protein (NDIP), crude protein (CP), zein, and prolamin closely correlated with the digestibility of high-moisture corn. The study’s findings demonstrate that inoculating L. buchneri and potassium sorbate can improve the quality of high-moisture corn silage fermentation and digestibility in different hybrids. The results will provide insights for enhancing farm productivity and profitability in China.
Development and Characterization of Conductive Ink Composed of Graphite and Carbon Black for Application in Printed Electrodes
Authors: Cândido Thaís Cristina , Pereira Arnaldo César , da Silva Daniela Nunes
Published: December 2023

This work developed a conductive ink composed of carbonaceous material for printing electrochemical sensors. The optimized ink comprises graphite, carbon black, and nail polish, respectively (35.3:11.7:53%), as well as acetone as a solvent. The proportion was optimized with consideration of the binder’s solubilization, the ink’s suitability for the screen-printing process, and lower electrical resistance. The materials used, and the resulting ink, were analyzed by way of Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), Raman spectroscopy, electrochemical impedance spectroscopy (EIS), and cyclic voltammetry (CV). The charge transfer resistance (Rct) obtained was 0.348 kΩ. The conductive ink was used to print an electrode on a PET substrate, and a flexible and disposable electrode was obtained. The electroactive area obtained was 13.7 cm2, which was calculated by the Randles-Sevcik equation. The applicability of the device was demonstrated with a redox probe, providing a sensitivity of 0.02 µ A L mmol−1. The conductive ink has adequate homogeneity for producing electrodes using the screen-printing technique, with a low estimated production cost of $ 0.09 mL−1.
Interaction of Glutathione with MMACHC Arginine-Rich Pocket Variants Associated with Cobalamin C Disease: Insights from Molecular Modeling
Authors: Antony Priya , Baby Bincy , Ali Amanat , Vijayan Ranjit , Al Jasmi Fatma
Published: December 2023

Methylmalonic aciduria and homocystinuria type C protein (MMACHC) is required by the body to metabolize cobalamin (Cbl). Due to its complex structure and cofactor forms, Cbl passes through an extensive series of absorptive and processing steps before being delivered to mitochondrial methyl malonyl-CoA mutase and cytosolic methionine synthase. Depending on the cofactor attached, MMACHC performs either flavin-dependent reductive decyanation or glutathione (GSH)-dependent dealkylation. The alkyl groups of Cbl have to be removed in the presence of GSH to produce intermediates that can later be converted into active cofactor forms. Pathogenic mutations in the GSH binding site, such as R161Q, R161G, R206P, R206W, and R206Q, have been reported to cause Cbl diseases. The impact of these variations on MMACHC’s structure and how it affects GSH and Cbl binding at the molecular level is poorly understood. To better understand the molecular basis of this interaction, mutant structures involving the MMACHC-MeCbl-GSH complex were generated using in silico site-directed point mutations and explored using molecular dynamics (MD) simulations. The results revealed that mutations in the key arginine residues disrupt GSH binding by breaking the interactions and reducing the free energy of binding of GSH. Specifically, variations at position 206 appeared to produce weaker GSH binding. The lowered binding affinity for GSH in the variant structures could impact metabolic pathways involving Cbl and its trafficking.
High-Transmission Biomimetics Structural Surfaces Produced via Ultrafast Laser Manufacturing
Authors: Leng Rui-Zhe , Yun Bi , Chen Zhi-Hao , Chai Chen , Xu Wei-Wei , Yu Yan-Hao , Wang Lei
Published: December 2023

Inspired by periodically aligned micro/nanostructures on biological surfaces, researchers have been fabricating biomimetic structures with superior performance. As a promising and versatile tool, an ultrafast laser combined with other forms of processing technology has been utilized to manufacture functional structures, e.g., the biomimetic subwavelength structures to restrain the surface Fresnel reflectance. In this review paper, we interpret the biomimetic mechanism of antireflective subwavelength structures (ARSSs) for high-transmission windows. Recent advances in the fabrication of ARSSs with an ultrafast laser are summarized and introduced. The limitations and challenges of laser processing technology are discussed, and the future prospects for advancement are outlined, too.
Polydeoxyribonucleotides Pre-Clinical Findings in Bone Healing: A Scoping Review
Authors: Manfredini Mattia , Poli Pier Paolo , Beretta Mario , Pellegrini Matteo , Salina Federica Eugenia , Maiorana Carlo
Published: December 2023

Aim: Polydeoxyribonucleotide (PDRN) is a chain-like polymer derived from DNA. Recent in vitro and animal studies have showcased the beneficial impacts of PDRN on the process of bone mending, whether used on its own or in conjunction with other substances that aid in regeneration. This scoping review aims to synthesize the current understanding of how PDRNs influence bone healing. Materials and Methods: The studies included in the screening procedure were randomized controlled clinical trials (RCTs), both retrospective and prospective case–control studies, as well as in vitro and in vivo investigations. Articles were sourced from PubMed (MEDLINE), Scopus, EMBASE, Web of Science, and Google Scholar electronic databases using the following MeSH terms: (polydeoxyribonucleotide) and (bone) and (regeneration). Results: Initially, 228 articles were identified. Following the review process, a total of eight studies were ultimately examined. Among these, two were confined to laboratory studies, five were conducted on living organisms, and one encompassed both evaluations on living organisms and in vitro assessments. A descriptive qualitative approach was employed to present the data extracted from the studies that were included. Conclusions: PDRN has the potential to enhance the process of bone healing and the quantity of newly generated bone when combined with grafting materials. Future clinical studies are warranted to ascertain the appropriate clinical application of PDRN based on the dosage under consideration.
Exploring Meteorological Conditions and Microscale Temperature Inversions above the Great Barrier Reef through Drone-Based Measurements
Authors: Eckert Christian , Monteforte Kim I. , Harrison Daniel P. , Kelaher Brendan P.
Published: December 2023

Understanding the atmospheric conditions in remote areas contributes to assessing local weather phenomena. Obtaining vertical profiles of the atmosphere in isolated locations can introduce significant challenges for the deployment and maintenance of equipment, as well as regulatory obstacles. Here, we assessed the potential of consumer drones equipped with lightweight atmospheric sensors to collect vertical meteorological profiles off One Tree Island (Great Barrier Reef), located approximately 85 km off the east coast of Australia. We used a DJI Matrice 300 drone with two InterMet Systems iMet-XQ2 UAV sensors, capturing data on atmospheric pressure, temperature, relative humidity, and wind up to an altitude of 1500 m. These flights were conducted three times per day (9 a.m., 12 noon, and 3 p.m.) and compared against ground-based weather sensors. Over the Austral summer/autumn, we completed 72 flights, obtaining 24 complete sets of daily measurements of atmospheric characteristics over the entire vertical profile. On average, the atmospheric temperature and dewpoint temperature were significantly influenced by the time of sampling, and also varied among days. The mean daily temperature and dewpoint temperature reached their peaks at 3 p.m., with the temperature gradually rising from its morning low. The mean dewpoint temperature obtained its lowest point around noon. We also observed wind speed variations, but changes in patterns throughout the day were much less consistent. The drone-mounted atmospheric sensors exhibited a consistent warm bias in temperature compared to the reference weather station. Relative humidity showed greater variability with no clear bias pattern, indicating potential limitations in the humidity sensor’s performance. Microscale temperature inversions were prevalent around 1000 m, peaking around noon and present in approximately 27% of the profiles. Overall, the drone-based vertical profiles helped characterise atmospheric dynamics around One Tree Island Reef and demonstrated the utility of consumer drones in providing cost-effective meteorological information in remote, environmentally sensitive areas.
Professional Teacher Identity on the Boundary: Student Study Group Facilitators Negotiating Their Identity
Authors: Arendale David R. , Hane Amanda R.
Published: December 2023

This study focuses on undergraduate student paraprofessionals who facilitated peer study groups for academically challenging college courses. A grounded qualitative research study of these student facilitators at an institution identified their professional identity development in unexpected ways that went against written policies for teacher attitudes and behaviors. Rather than perceiving themselves as peer study group facilitators following a narrow job description, many of them referred to themselves as teachers and acted accordingly, breaking the boundaries of behavior established by the study group program administrator. This article unmasks this professional identity emergence, postulates the mechanism for this choice, presents a model to explain it, and makes recommendations for talking openly about this identity and the subsequent behaviors that occurred as a result by the facilitators and the implications for the PAL program.
Environmental Impact Assessment of Plastic Waste Management Scenarios in the Canadian Context
Authors: Zhang Ophela , Takaffoli Mahdi , Ertz Myriam , Addar Walid
Published: December 2023

Given the scale of plastic generation, its persistent presence in the environment, and the urgent need to transition to a net-zero emissions paradigm, managing plastic waste has gained increasing attention globally. Developing an effective strategy for plastic waste management requires a comprehensive assessment of the potential benefits offered by different solutions, particularly with respect to their environmental impact. This study employs the life cycle assessment (LCA) methodology to evaluate the environmental impact of two alternative scenarios to the As-Is scenario for managing plastic waste in the province of British Columbia in Canada. The LCA results suggest that the Zero Plastic Waste scenario, which heavily relies on chemical recycling, may not inherently result in a reduced environmental footprint across all impact categories. This is notable when the focus is solely on end-of-life treatment processes, without considering the produced products and energy. The Intermediate scenario reduces the amount of plastic waste sent to landfills by directing more end-of-life plastic to mechanical recycling facilities. This scenario provides immediate benefits for resource conservation, with a minimal increase in the environmental burden resulting from treatment processes. Nonetheless, achieving a net-zero transition requires combining traditional and emerging recycling technologies. The current study could offer some guidance to policymakers on strategies for fostering more sustainable management of plastic waste.
Difference in Aroma Components of Black Teas Processed on Different Dates in the Spring Season
Authors: Yu Penghui , Huang Yingjie , Li Ziyi , Zhao Xi , Huang Hao , Zhong Ni , Zheng Hongfa , Chen Qincao
Published: December 2023

Tea aroma greatly varies with the production date. This study investigated the aroma differences among black teas processed on different dates (March 23rd, April 8th, April 15th, April 27th, and May 7th) in the spring. A sensory evaluation showed that the black tea produced on April 15th had a strong and lasting sweet aroma and the highest score of 93.5. In total, 71 volatile compounds were identified, and alcohols were the predominant category, accounting for 60.98%. From March 23rd to May 7th, the total content of volatile compounds showed a parabolic change trend and reached its maximum on April 15th (715.27 μg/L); the flavor index first peaked on April 8th (23.25) and then gradually decreased. A multivariate statistical analysis showed that 39 volatile compounds were important, differential aroma components. An odor activity value (OAV) analysis showed that the predominant odorants were β-ionone, β-damascenone, linalool, (E)-β-ocimene, and geraniol, all with values larger than 100. The total OAVs of undesirable odorants decreased and reached their minimum (70.4) on April 27th, while the total OAVs of pleasant odorants and the ratio of pleasant/undesirable odorants showed inverse changes and reached their maximum (2182.1 and 31.0, respectively) on April 27th. Based on the significance of differences and OAVs, linalool, (E)-β-ocimene, geraniol, and (E,E)-2,4-nonadienal were considered as the key differential odorants. Combined with the sensory evaluation and the differences in aroma components, it was proposed that black teas produced around April 15th in the Hunan district are more likely to have a strong and lasting sweet aroma. This study will provide scientific guidance for the production of black tea in the Hunan district, China.
Comparative Metabolomics Analysis of Different Perilla Varieties Provides Insights into Variation in Seed Metabolite Profiles and Antioxidant Activities
Authors: Dossou Senouwa Segla Koffi , Deng Qianchun , Li Feng , Jiang Nanjun , Zhou Rong , Wang Lei , Li Donghua , Tan Meilian , You Jun , Wang Linhai
Published: December 2023

Perilla seeds are essential functional foods and key ingredients in traditional medicine. Herein, we investigated the variation in phytochemical profiles and antioxidant activities of twelve different perilla seeds. The seeds showed significant variations in total phenolic and flavonoid contents ranging from 16.92 to 37.23 mg GAE/g (GAE, gallic acid equivalent) and 11.6 to 19.52 mg CAE/g (CAE, catechin equivalent), respectively. LC-QqQ-MS (liquid chromatography triple quadrupole tandem mass spectrometry)-based widely targeted metabolic profiling identified a total of 975 metabolites, including 68–269 differentially accumulated metabolites (DAMs). Multivariate analyses categorized the seeds into four groups based on the seed coat and leaf colors. Most key bioactive DAMs, including flavonoids (quercetin-3’-O-glucoside, prunin, naringenin, naringenin chalcone, butin, genistin, kaempferol-3-O-rutinoside, etc.), amino acids (valine, lysine, histidine, glutamine, threonine, etc.), and vitamins (B1, B3, B6, U, etc.) exhibited the highest relative content in PL3 (brown seed, purple leaf), PL1 (white seed, green-purple leaf), and PL4 (white seed, green leaf) groups, respectively. Meanwhile, key differentially accumulated phenolic acids showed a higher relative content in PL1 and PL4 than in other groups. Both seeds exhibited high antioxidant activities, although those of PL2 (brown seed, green leaf) group seeds were the lowest. Our results may facilitate the comprehensive use of perilla seeds in food and pharmaceutical industries.
Family Name Adoption in the Dutch Colonies at the Abolition of Slavery in the Context of National Family Name Legislation: A Reflection on Contemporary Name Change
Authors: Brouwer Leendert
Published: December 2023

Name change can only take place in the Netherlands under strict conditions and according to patronizing regulations. At the moment, an amendment of name law is being drafted that would give descendants of Dutch citizens whose ancestors lived in slavery an exemption. If they have a family name that their ancestors received upon their release, they may change it free of charge. It remains to be seen, however, whether the desire to adopt new names in keeping with a reclaimed African identity can also be granted. After all, that would conflict with the general regulations when creating a new name. The whole issue shows political opportunism. First, it would be useful to get a good picture of name adoption in light of surnaming in general. Is it right to consider the names in question as slave names? Are they really that bad? It is more likely that precisely the exceptional position now obtained leads to undesirable profiling. In fact, the only solution to embarrass no one is a wholesale revision of the name law that does away with outdated 19th century limitations. Why should anyone be unhappy with their name? Why should someone who insists on having a different name be prevented from doing so? This essay examines the announced change in the law against the background of surnaming in general and the acquisition of family names in Suriname and the Netherlands Antilles in particular.
A Compendious Review on the Determination of Fundamental Site Period: Methods and Importance
Authors: Güllü Ahmet
Published: December 2023

It is now well-known that ground motion characteristics can be influenced significantly by local site characteristics. In general, soil characteristics were classified by considering the time-average velocity down to 30 m (Vs30). However, recent studies have showed that the fundamental site period is a better proxy than Vs30, or the most complementary parameter to Vs30, for this purpose. Recent earthquakes have also revealed that the largest amplifications occur at the fundamental site period and cause heavy damage or the collapse of structures when they have similar vibrational characteristics with the site’s fundamental period, i.e., resonance. Therefore, many studies in the literature have been performed to determine the fundamental periods of layered soil profiles using different analytical, approximate, and data-driven methods. However, there is a requirement to evaluate these methods by following a systematic procedure. Hence, the reader will receive a comprehensive review of the available procedures for determining the site’s fundamental period of layered soil profiles and their applications at different scales, along with an exploration of current research gaps.
Task-Oriented Training with Abdominal Drawing-in Maneuver in Sitting Position for Trunk Control, Balance, and Activities of Daily Living in Patients with Stroke: A Pilot Randomized Controlled Trial
Authors: Jeong Seunghoon , Chung Yijung
Published: December 2023

In many patients with stroke, trunk stabilization and balance are decreased. Trunk stabilization and balance are important to perform posture control and functional movement. This study investigates the effects of task-orientated training with the abdominal drawing-in maneuver in a sitting position on trunk control, balance, and activities of daily living in patients with chronic stroke. The study design is a randomized controlled trial. Thirty-eight patients with chronic stroke participated in this study. The task-oriented training combined with the abdominal drawing-in maneuver group (n = 13), the task-oriented training group (n = 13), and the control group (n = 12) received traditional physical therapy. Three groups participated in a total of 20 sessions, four times a week for five weeks. After the five-week training period, trunk control, balance, and activities of daily living were assessed. The task-oriented training combined with the abdominal drawing-in maneuver group demonstrated significant improvements in trunk control, balance, and activities of daily living compared to the task-oriented training and control groups (p < 0.05). These results have implications for improving trunk control, balance, and activities of daily living for patients with stroke, and support the integration of this training method into standard clinical practice.
Adult Attachment and Fear of Missing Out: Does the Mindful Attitude Matter?
Authors: Perazzini Matteo , Bontempo Danilo , Giancola Marco , D’Amico Simonetta , Perilli Enrico
Published: December 2023

Fear of missing out (FoMO) involves the desire or urge to stay continuously connected to and kept up-to-date with a social reference group. The present study explored the relationships between adult attachment and FoMO and the potential mediating effect of a mindful attitude. The present study was carried out on 192 participants (meanage = 23.24 years; SDage = 4.33 years), of whom 151 (78.6%) were female and the remaining 41 (21.4%) were male. The participants completed the Adult Attachment Scale—Revised (AAS-R), which evaluates Close, Depend, and Anxiety attachment, the Cognitive and Affective Mindfulness Scale—Revised (CAMS-R) and the Fear of Missing Out Scale (FoMOs). The results indicated that the three forms of adult attachment (Close, Depend, and Anxiety) were associated with FoMO through the indirect effect of mindful attitudes. This study yielded relevant theoretical and practical implications regarding the critical role of a mindful attitude as a protective factor against FoMO. Limitations and future research directions were also discussed.
Evaluation of the Efficacy of UV-C Radiation in Eliminating Microorganisms of Special Epidemiological Importance from Touch Surfaces under Laboratory Conditions and in the Hospital Environment
Authors: Różańska Anna , Walkowicz Monika , Bulanda Małgorzata , Kasperski Tomasz , Synowiec Edyta , Osuch Piotr , Chmielarczyk Agnieszka
Published: December 2023

Introduction: Healthcare-associated infections in the post-pandemic era are as important as they were before COVID-19. The dominant route of transmission of microorganisms in health care units is the contact route, for which hand hygiene is of cardinal importance, but also effective disinfection of touch surfaces. Traditional disinfection based on chemical compounds is sensitive to human errors. Therefore, a valuable supplement to it can be contactless disinfection methods, including the use of UV-C. The aim of the study was to assess the effectiveness of UV-C radiation in eliminating selected, most important pathogens of particular epidemic importance from surfaces made of various materials: stainless steel, plastic and glass, most often found in hospital conditions. Material and Method: In laboratory conditions, the study was conducted using bacterial strains of great epidemiological importance and Candida auris. In hospital wards, samples were taken before and after disinfection for comparisons of the composition and quantity of bacteria. In laboratory conditions, carriers made of steel, plastic and glass were contaminated with a bacterial suspension with a density of approx. 0.5 McFarland, and then the density of persistent microorganisms was assessed after 10 min of UV-C irradiation. Results: The high effectiveness of UV-C radiation in eliminating bacteria contaminating touch surfaces in hospital wards and in laboratory conditions has been confirmed. The elimination efficiency in laboratory conditions was slightly lower (statistically insignificant) on the plastic surface, which is probably related to subtle differences in the thickness of the contaminating layer. Hydrophobic properties and the smallest suspension diameter were confirmed for the tested plastic carriers. Conclusions: UV-C disinfection is a desirable element to support traditional, chemical methods of disinfection in hospital conditions, effective against multidrug-resistant bacteria and C. auris.
Assessment of Oral Health Knowledge, Attitudes, and Behaviours among University Students in the Asir Region—Saudi Arabia: A Cross-Sectional Study
Authors: Kandasamy Geetha , Almeleebia Tahani
Published: December 2023

Background: The purpose of this study is to evaluate the knowledge, attitudes, and behaviours (KAB) of health and non-health-related students at university concerning oral health. Materials and Methods: This cross-sectional study with a 3-month duration in 2023 was conducted amongst King Khalid University (KKU) students. This study used a self-administered, anonymous web-based survey with a simple random sampling strategy as part of its cross-sectional design. The questionnaire had four sections totalling 26 questions to evaluate KAB. A chi-square test was used to evaluate significant differences between categories. Results: Of the 845 respondents who completed the survey, 43.78% were health-related students, while 56.21% were non-health-related students. The completed responses included bacteria causing gingival problems (60.81% vs. 36%), fizzy soft drinks adversely affecting teeth (67.83% vs. 40%), tobacco chewing or smoking possibly causing oral cancer (68.37% vs. 44%), white patches or dental plaque on teeth (61.89% vs. 41.47%), brushing teeth twice a day to improve oral health (81.62% vs. 42.52%), keeping teeth clean (64.86% vs. 41.68%), improper brushing leading to gum disease (70% vs. 40.63%), brushing with fluoridated toothpaste to prevent tooth decay (63% vs. 40%), bleeding gums denoting gum infection (26.98% vs. 21.30%), the importance of teeth similar to any body part (61.62% vs. 37.89%), prioritising teeth as other parts of the body (61.05% vs. 36.21%), brushing teeth twice daily (55.67% vs. 37.05%), and routine dental check-ups (55.40% vs. 14.10%) for health and non-health-related students, respectively (p < 0.05). Conclusion: The results of the current study demonstrated less oral health KAB in non-health-related students than in health-related students. Nonetheless, healthcare students provided erroneous information regarding oral health. Therefore, we urge the appropriate authorities to offer health and non-health-related students the best oral health promotion programmes and services, thereby seeking to improve their oral health knowledge while stressing the importance of practising excellent oral hygiene.
Operational Modal Analysis on Bridges: A Comprehensive Review
Authors: Hasani Hamed , Freddi Francesco
Published: December 2023

Structural health monitoring systems have been employed throughout history to assess the structural responses of bridges to both natural and man-made hazards. Continuous monitoring of the integrity and analysis of the dynamic characteristics of bridges offers a solution to the limitations of visual inspection approaches and is of paramount importance for ensuring long-term safety. This review article provides a thorough, straightforward examination of the complete process for performing operational modal analysis on bridges, covering everything from data collection and preprocessing to the application of numerous modal identification techniques in both the time and frequency domains. It also incorporates advanced methods to address and overcome challenges encountered in previous approaches. The paper is distinguished by its thorough examination of various methodologies, highlighting their specific advantages and disadvantages, and providing concrete illustrations of their implementation in practical settings.