bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables 1 - 2 from BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition
Authors: Hutchinson Katherine E. , Lipson Doron , Stephens Philip J. , Otto Geoff , Lehmann Brian D. , Lyle Pamela L. , Vnencak-Jones Cindy L. , Ross Jeffrey S. , Pietenpol Jennifer A. , Sosman Jeffrey A. , Puzanov Igor , Miller Vincent A. , Pao William
Published: April 2023

PDF file - 86K, Supplementary Table S1. 52 Melanomas from Various Institutions Genotyped by FoundationOne(TM). Supplementary Table S2. Primers used to clone WT PAPSS1, WT TRIM24, PAPSS1-BRAF and TRIM24-BRAF.
Supplementary Materials, Methods, Figures and Table legends from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
Authors: Chiang Cheryl Lai-Lai , Kandalaft Lana E. , Tanyi Janos , Hagemann Andrea R. , Motz Gregory T. , Svoronos Nikolaos , Montone Kathleen , Mantia-Smaldone Gina M. , Smith Lori , Nisenbaum Harvey L. , Levine Bruce L. , Kalos Michael , Czerniecki Brian J. , Torigian Drew A. , Powell Daniel J. , Mick Rosemarie , Coukos George
Published: April 2023

Supplementary Materials, Methods, Figures and Table legends - PDF file 87K, Supplementary file giving details of supplementary materials and methods, figure legends and table legends
Supplementary Figure Legend from BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition
Authors: Hutchinson Katherine E. , Lipson Doron , Stephens Philip J. , Otto Geoff , Lehmann Brian D. , Lyle Pamela L. , Vnencak-Jones Cindy L. , Ross Jeffrey S. , Pietenpol Jennifer A. , Sosman Jeffrey A. , Puzanov Igor , Miller Vincent A. , Pao William
Published: April 2023

PDF file - 83K
Supplementary Figure S4 from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
Authors: Chiang Cheryl Lai-Lai , Kandalaft Lana E. , Tanyi Janos , Hagemann Andrea R. , Motz Gregory T. , Svoronos Nikolaos , Montone Kathleen , Mantia-Smaldone Gina M. , Smith Lori , Nisenbaum Harvey L. , Levine Bruce L. , Kalos Michael , Czerniecki Brian J. , Torigian Drew A. , Powell Daniel J. , Mick Rosemarie , Coukos George
Published: April 2023

Supplementary Figure S4 - PDF file 84K, A-B, Quantification of % Treg cells in subjects' pre- and post-vaccine PBMCs. C, fold-increase in serum cytokines and chemokines of subjects at EOS. Line indicated a 1 fold-increase from 1st OCDC vaccine to EOS
Supplementary Figure S2 from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
Authors: Chiang Cheryl Lai-Lai , Kandalaft Lana E. , Tanyi Janos , Hagemann Andrea R. , Motz Gregory T. , Svoronos Nikolaos , Montone Kathleen , Mantia-Smaldone Gina M. , Smith Lori , Nisenbaum Harvey L. , Levine Bruce L. , Kalos Michael , Czerniecki Brian J. , Torigian Drew A. , Powell Daniel J. , Mick Rosemarie , Coukos George
Published: April 2023

Supplementary Figure S2 - PDF file 84K, Phenotype of DCs following lysate-pulsing (i.e. HOCl-L, UVB-L or FTL), and activation with LPS and IFN-gamma. Unpulsed, mature (mDC) or immature DCs (iDC) served as controls. Data was presented as mean plus-minus SEM
Supplementary Tables 1-3 from Activation of the mTOR Pathway in Primary Medullary Thyroid Carcinoma and Lymph Node Metastases
Authors: Tamburrino Anna , Molinolo Alfredo A. , Salerno Paolo , Chernock Rebecca D. , Raffeld Mark , Xi Liqiang , Gutkind J. Silvio , Moley Jeffrey F. , Wells Samuel A. , Santoro Massimo
Published: April 2023

PDF file - 138K, Table S1. Characteristics of 53 MTC (hereditary or sporadic) cases for which the RAS/MEK/ERK and PI3K/AKT/mTOR pathways were studied; Table S2. Study of MTC samples for RET and RAS mutation status and for immunoreactivity for pS6, pAKT and Perk; Table S3. Antibodies used for immunohistochemistry
Supplementary Table 3 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer
Authors: Marchini Sergio , Poynor Elizabeth , Barakat Richard R. , Clivio Luca , Cinquini Michela , Fruscio Robert , Porcu Luca , Bussani Cecilia , D’Incalci Maurizio , Erba Eugenio , Romano Michela , Cattoretti Giorgio , Katsaros Dionyssios , Koff Andrew , Luzzatto Lucio
Published: April 2023

PDF file, 61K, qRT-PCR and densitometric analysis of ZIC2 expression. R is the ratio of the median distribution of ZIC2 expression levels measured by real time qRT-PCR or Western Blot in the MAL biopsies compared to the LMP biopsies or between stage III versus stage I. For each dataset, the ZIC2 median and the 25-75th percentiles are reported (IQ-range). p is the level of significance according to the Mann-Whitney t test (p<0.05). ZIC2 mRNA values are thousands of molecules/input RNA.
Supplementary Table 2 from MSH3 Protein Expression and Nodal Status in MLH1-Deficient Colorectal Cancers
Authors: Laghi Luigi , Bianchi Paolo , Delconte Gabriele , Celesti Giuseppe , Di Caro Giuseppe , Pedroni Monica , Chiaravalli Anna Maria , Jung Barbara , Capella Carlo , de Leon Maurizio Ponz , Malesci Alberto
Published: April 2023

PDF file, 80KB, Supplemental material 4. Tumor Features Associated with Nodal Involvement (N1or N2) at Pathological Staging of 71 MLH1 Deficient MSI CRC.
CCR Translation for This Article from Cytoplasmic Estrogen Receptor in Breast Cancer
Authors: Welsh Allison W. , Lannin Donald R. , Young Gregory S. , Sherman Mark E. , Figueroa Jonine D. , Henry N. Lynn , Ryden Lisa , Kim Chungyeul , Love Richard R. , Schiff Rachel , Rimm David L.
Published: April 2023

CCR Translation for This Article from Cytoplasmic Estrogen Receptor in Breast Cancer
Supplementary Figure Legend from Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice
Authors: Fan Haitao , Zhang Ian , Chen Xuebo , Zhang Leying , Wang Huaqing , Da Fonseca Anna , Manuel Edwin R. , Diamond Don J. , Raubitschek Andrew , Badie Behnam
Published: April 2023

PDF file, 66K.
Supplementary Figure 3 from Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice
Authors: Fan Haitao , Zhang Ian , Chen Xuebo , Zhang Leying , Wang Huaqing , Da Fonseca Anna , Manuel Edwin R. , Diamond Don J. , Raubitschek Andrew , Badie Behnam
Published: April 2023

PDF file, 128K, Depletion of myeloid-derived suppressive cells.
Supplementary Figure 1 from FoxM1 Inhibition Sensitizes Resistant Glioblastoma Cells to Temozolomide by Downregulating the Expression of DNA-Repair Gene Rad51
Authors: Zhang Nu , Wu Xinjian , Yang Lixuan , Xiao Feizhe , Zhang Heng , Zhou Aidong , Huang Zhengsong , Huang Suyun
Published: April 2023

PDF file - 161K, Supplementary Fig.1. FoxM1 is upregulated in recurrent GBMs and correlated with DNA damage genes
Supplementary Figure 1 from Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice
Authors: Fan Haitao , Zhang Ian , Chen Xuebo , Zhang Leying , Wang Huaqing , Da Fonseca Anna , Manuel Edwin R. , Diamond Don J. , Raubitschek Andrew , Badie Behnam
Published: April 2023

PDF file, 73K, In vitro CNT-CpG activity assay.
Supplementary Figure Legends 1-5 from hVps37A Status Affects Prognosis and Cetuximab Sensitivity in Ovarian Cancer
Authors: Wittinger Michael , Vanhara Petr , El-Gazzar Ahmed , Savarese-Brenner Bettina , Pils Dietmar , Anees Mariam , Grunt Thomas W. , Sibilia Maria , Holcmann Martin , Horvat Reinhard , Schemper Michael , Zeillinger Robert , Schöfer Christian , Dolznig Helmut , Horak Peter , Krainer Michael
Published: April 2023

PDF file - 81K
Data Supplement from Functional p38 MAPK Identified by Biomarker Profiling of Pancreatic Cancer Restrains Growth through JNK Inhibition and Correlates with Improved Survival
Authors: Zhong Yi , Naito Yoshiki , Cope Leslie , Naranjo-Suarez Salvador , Saunders Tyler , Hong Seung-Mo , Goggins Michael G. , Herman Joseph M. , Wolfgang Christopher L. , Iacobuzio-Donahue Christine A.
Published: April 2023

Supplemental Figure 5. Solvent Tests of Cell Lines.
Supplementary Figure 4 from hVps37A Status Affects Prognosis and Cetuximab Sensitivity in Ovarian Cancer
Authors: Wittinger Michael , Vanhara Petr , El-Gazzar Ahmed , Savarese-Brenner Bettina , Pils Dietmar , Anees Mariam , Grunt Thomas W. , Sibilia Maria , Holcmann Martin , Horvat Reinhard , Schemper Michael , Zeillinger Robert , Schöfer Christian , Dolznig Helmut , Horak Peter , Krainer Michael
Published: April 2023

PDf file - 99K
Supplementary Table 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
Authors: Madic Jordan , Piperno-Neumann Sophie , Servois Vincent , Rampanou Aurore , Milder Maud , Trouiller Bénédicte , Gentien David , Saada Stéphanie , Assayag Franck , Thuleau Aurélie , Nemati Fariba , Decaudin Didier , Bidard François-Clément , Desjardins Laurence , Mariani Pascale , Lantz Olivier , Stern Marc-Henri
Published: April 2023

PDF file, 26KB, Biological and imaging characteristics in the 21 metastatic uveal melanoma patients.
Supplementary Figure 1 from hVps37A Status Affects Prognosis and Cetuximab Sensitivity in Ovarian Cancer
Authors: Wittinger Michael , Vanhara Petr , El-Gazzar Ahmed , Savarese-Brenner Bettina , Pils Dietmar , Anees Mariam , Grunt Thomas W. , Sibilia Maria , Holcmann Martin , Horvat Reinhard , Schemper Michael , Zeillinger Robert , Schöfer Christian , Dolznig Helmut , Horak Peter , Krainer Michael
Published: April 2023

PDF file - 55K
Supplementary Table 1 from Mutual Regulation between Raf/MEK/ERK Signaling and Y-Box–Binding Protein-1 Promotes Prostate Cancer Progression
Authors: Imada Kenjiro , Shiota Masaki , Kohashi Kenichi , Kuroiwa Kentaro , Song YooHyun , Sugimoto Masaaki , Naito Seiji , Oda Yoshinao
Published: April 2023

Supplementary Table 1. Relationship between expressions of YB-1, p-YB-1, and ERK2, and clinicopathological characteristics - XLSX file 12K, *Statistically significant
Supplementary Figure 8 from Targeted Therapy for BRAFV600E Malignant Astrocytoma
Authors: Nicolaides Theodore P. , Li Huifang , Solomon David A. , Hariono Sujatmi , Hashizume Rintaro , Barkovich Krister , Baker Suzanne J. , Paugh Barbara S. , Jones Chris , Forshew Tim , Hindley Guy F. , Hodgson J. Graeme , Kim Jung-Sik , Rowitch David H. , Weiss William A. , Waldman Todd A. , James C. David
Published: April 2023

PDF file - 222K
Supplementary Table 1 from Expression Profiling of Archival Tumors for Long-term Health Studies
Authors: Waldron Levi , Ogino Shuji , Hoshida Yujin , Shima Kaori , McCart Reed Amy E. , Simpson Peter T. , Baba Yoshifumi , Nosho Katsuhiko , Segata Nicola , Vargas Ana Cristina , Cummings Margaret C. , Lakhani Sunil R. , Kirkner Gregory J. , Giovannucci Edward , Quackenbush John , Golub Todd R. , Fuchs Charles S. , Parmigiani Giovanni , Huttenhower Curtis
Published: April 2023

PDF file - 31K, Supplemental Table S1: Correlation between mRNA expression and status of protein expression, promoter CpG island methylation, or other tumor biomarker status.
Supplementary Table 1 from Analysis of Receptor Tyrosine Kinase ROS1-Positive Tumors in Non–Small Cell Lung Cancer: Identification of a FIG-ROS1 Fusion
Authors: Rimkunas Victoria M. , Crosby Katherine E. , Li Daiqiang , Hu Yerong , Kelly Meghan E. , Gu Ting-Lei , Mack Jennifer S. , Silver Matthew R. , Zhou Xinmin , Haack Herbert
Published: April 2023

XLSX file, 43KB, RT-PCR Results for FFPE ROS positive tumors.
CCR Translation for This Article from Analysis of Receptor Tyrosine Kinase ROS1-Positive Tumors in Non–Small Cell Lung Cancer: Identification of a FIG-ROS1 Fusion
Authors: Rimkunas Victoria M. , Crosby Katherine E. , Li Daiqiang , Hu Yerong , Kelly Meghan E. , Gu Ting-Lei , Mack Jennifer S. , Silver Matthew R. , Zhou Xinmin , Haack Herbert
Published: April 2023

CCR Translation for This Article from Analysis of Receptor Tyrosine Kinase ROS1-Positive Tumors in Non–Small Cell Lung Cancer: Identification of a FIG-ROS1 Fusion
Supplementary Figure Legend from IL-17–Mediated M1/M2 Macrophage Alteration Contributes to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws
Authors: Zhang Qunzhou , Atsuta Ikiru , Liu Shiyu , Chen Chider , Shi Shihong , Shi Songtao , Le Anh D.
Published: April 2023

PDF file - 80K
Data Supplement from PBX1 Is a Favorable Prognostic Biomarker as It Modulates 13-cis Retinoic Acid–Mediated Differentiation in Neuroblastoma
Authors: Shah Nilay , Wang Jianjun , Selich-Anderson Julia , Graham Garrett , Siddiqui Hasan , Li Xin , Khan Javed , Toretsky Jeffrey
Published: April 2023

Supplementary Figure 1a: Prototypical examples of retinoid-sensitive and resistant cell lines; 1b: TALE family gene expression across 15-cell line panel.
Supplementary Table 8 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 93K, Distribution of the PAM50 intrinsic subtypes based on RORP score groups.
Supplementary Table 7 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 105K, Ability of the high RORP group to predict pCR in 91 patients with clinically HER2-positive disease treated with trastuzumab-based chemotherapy in the ISPY-1, MDACC and XeNA studies.
Supplementary Table 4 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 102K, Clinical-pathological characteristics of the various pathology-defined subtypes.
Supplementary Figure 4 from Regulation of Colorectal Carcinoma Stemness, Growth, and Metastasis by an miR-200c-Sox2–Negative Feedback Loop Mechanism
Authors: Lu Yan-Xia , Yuan Li , Xue Xiao-Lei , Zhou Min , Liu Yan , Zhang Chao , Li Jing-Ping , Zheng Lin , Hong Min , Li Xue-Nong
Published: April 2023

PDF file - 511KB, Showed that cancer stem cell markers and miR-200c was evaluated in tumour xenografts, and the metastatic liver nodules was quantitated.
Supplementary Table 1 from Colonization of the Human Gut by E. coli and Colorectal Cancer Risk
Authors: Bonnet Mathilde , Buc Emmanuel , Sauvanet Pierre , Darcha Claude , Dubois Damien , Pereira Bruno , Déchelotte Pierre , Bonnet Richard , Pezet Denis , Darfeuille-Michaud Arlette
Published: April 2023

PDF file - 47K, Table A: The presence of mucosa-associated or internalized E. coli in the tissues of colon 542 cancer patients according to clinical characteristics.
Supplementary Figures 1 - 3 from Colonization of the Human Gut by E. coli and Colorectal Cancer Risk
Authors: Bonnet Mathilde , Buc Emmanuel , Sauvanet Pierre , Darcha Claude , Dubois Damien , Pereira Bruno , Déchelotte Pierre , Bonnet Richard , Pezet Denis , Darfeuille-Michaud Arlette
Published: April 2023

PDF file - 1963K, Figure A: TNM stage in relation to the mucosal proliferative index measured by Ki-67 immunostaining. Figure B: Colonization of the mucosa or tumor by E. coli in relation to the presence of B2 phylotype E. coli strains. Figure C: Colonization of the mucosa or tumor by E. coli in relation to the presence of cyclomodulin-encoded genes.
Supplementary Figure 4 from FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
Authors: Cui Jiujie , Shi Min , Xie Dacheng , Wei Daoyan , Jia Zhiliang , Zheng Shaojiang , Gao Yong , Huang Suyun , Xie Keping
Published: April 2023

PDF file - 894KB, Supplementary Fig. S4. Concomitant expressions of FOXM1 and LDHA in TMA.
Supplementary Figure 2 from FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
Authors: Cui Jiujie , Shi Min , Xie Dacheng , Wei Daoyan , Jia Zhiliang , Zheng Shaojiang , Gao Yong , Huang Suyun , Xie Keping
Published: April 2023

PDF file - 185KB, Supplementary Fig. S2. FOXM1 regulates glucose utilization.
Supplement Table 1 from Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study
Authors: Wang Jiping , Carvajal-Carmona Luis G. , Chu Jen-Hwa , Zauber Ann G. , Kubo Michikai , Matsuda Koichi , Dunlop Malcolm , Houlston Richard S. , Sieber Oliver , Lipton Lara , Gibbs Peter , Martin Nicholas G. , Montgomery Grant W. , Young Joanne , Baird Paul N. , Ratain Mark J. , Nakamura Yusuke , Weiss Scott T. , Tomlinson Ian , Bertagnolli Monica M.
Published: April 2023

Supplement Table 1
Supplementary Figure 2 from Quantitative Measurements of Tumoral p95HER2 Protein Expression in Metastatic Breast Cancer Patients Treated with Trastuzumab: Independent Validation of the p95HER2 Clinical Cutoff
Authors: Duchnowska Renata , Sperinde Jeff , Chenna Ahmed , Haddad Mojgan , Paquet Agnes , Lie Yolanda , Weidler Jodi M. , Huang Weidong , Winslow John , Jankowski Tomasz , Czartoryska-Arłukowicz Bogumiła , Wysocki Piotr J. , Foszczyńska-Kłoda Małgorzata , Radecka Barbara , Litwiniuk Maria M. , Żok Jolanta , Wiśniewski Michał , Zuziak Dorota , Biernat Wojciech , Jassem Jacek
Published: April 2023

PDF file - 1729KB, Supplemental Figure S2. Kaplan-Meier plots for p95 IHC categories within the HER2 overexpressed subset (H2T>13.8 RF/mm2) with p95 IHC 0 in green, 1+ in red, 2+ in black and 3+ in blue. A, Progression free survival. B, Overall survival. C, Progression free survival in the hormone receptor positive subgroup.
Supplement Figure 2 from Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study
Authors: Wang Jiping , Carvajal-Carmona Luis G. , Chu Jen-Hwa , Zauber Ann G. , Kubo Michikai , Matsuda Koichi , Dunlop Malcolm , Houlston Richard S. , Sieber Oliver , Lipton Lara , Gibbs Peter , Martin Nicholas G. , Montgomery Grant W. , Young Joanne , Baird Paul N. , Ratain Mark J. , Nakamura Yusuke , Weiss Scott T. , Tomlinson Ian , Bertagnolli Monica M.
Published: April 2023

Supplement Figure 2
Supplementary Table 1 from Serial Diffusion MRI to Monitor and Model Treatment Response of the Targeted Nanotherapy CRLX101
Authors: Ng Thomas S.C. , Wert David , Sohi Hargun , Procissi Daniel , Colcher David , Raubitschek Andrew A. , Jacobs Russell E.
Published: April 2023

PDF file - 74K, P-values of histological comparisons of CRLX101 and CPT-11 cohorts with controls on different days. Statistically significant values are highlighted (p < 0.01, *, p < 0.05, �).
Related Article from Stressing the Development of Small Molecules Targeting HSP90
Authors: Neckers Len , Trepel Jane B.
Published: April 2023

Related Article from Stressing the Development of Small Molecules Targeting HSP90
Supplementary Figure 1 from Serial Diffusion MRI to Monitor and Model Treatment Response of the Targeted Nanotherapy CRLX101
Authors: Ng Thomas S.C. , Wert David , Sohi Hargun , Procissi Daniel , Colcher David , Raubitschek Andrew A. , Jacobs Russell E.
Published: April 2023

PDF file - 64K, Boxplots of cellular proliferation rates for different treatment groups calculated by applying ADC data to a logistic model of tumor growth. Boxplots for (A) control, (B) CRLX101 and (C) CPT-11 animals between day 0/2, day 0/4, day 2/4, and day 4/7 are shown.
Supplementary Tables 1 - 2 from Activity of the Hypoxia-Activated Prodrug, TH-302, in Preclinical Human Acute Myeloid Leukemia Models
Authors: Portwood Scott , Lal Deepika , Hsu Yung-Chun , Vargas Rodrigo , Johnson Megan K. , Wetzler Meir , Hart Charles P. , Wang Eunice S.
Published: April 2023

PDF file - 66K, Supplemental Table 1. Cell cycle analysis of AML cells treated with TH-302. AML cells were treated with vehicle (PBS) or TH- 302 at the indicated concentrations for 24 hours under hypoxic (1% O2) or normoxic (21% O2) conditions in triplicate wells. Cells were stained with propidium iodide staining and analyzed by flow cytometry. Mean plus-minus SEM percentages of cells in each cell cycle phase are shown. Similar results were obtained in three independent experiments. Supplemental Table 2. TH-302 induces dose and hypoxia-dependent apoptosis in representative human AML cell lines. Shown are the mean plus-minus SEM percentages of total apoptotic and dead cells as determined by flow cytometry for 7-AAD/annexin-V expression in a panel of seven human AML cell lines. Known molecular and cytogenetic characteristics of each cell line is provided. Cells were incubated with vehicle or TH-302 at doses ranging from 0.1-10 μM under normoxia (21% O2) or hypoxia (1% O2) for 72 hours. Cells were plated in multiple wells per condition with summarized results of at least two independent experiments provided. Results of student t test analysis comparing results under normoxia vs. hypoxia are provided.
Supplementary Figure 4 from Activity of the Hypoxia-Activated Prodrug, TH-302, in Preclinical Human Acute Myeloid Leukemia Models
Authors: Portwood Scott , Lal Deepika , Hsu Yung-Chun , Vargas Rodrigo , Johnson Megan K. , Wetzler Meir , Hart Charles P. , Wang Eunice S.
Published: April 2023

PDF file - 635K, Supplemental Figure 4. Hypoxia attenuates cytarabine-induced apoptosis of human AML cells. Hypoxia attenuates chemotherapy-induced apoptosis of human AML cells.
Supplementary Figures from Tumor-Reactive CD8+ T Cells in Metastatic Gastrointestinal Cancer Refractory to Chemotherapy
Authors: Turcotte Simon , Gros Alena , Tran Eric , Lee Chyi-Chia R. , Wunderlich John R. , Robbins Paul F. , Rosenberg Steven A.
Published: April 2023

PDF file 535K, Supp. Fig. S1 shows the immunocytochemical characterization of the new gastrointestinal cancer cell lines. Suppl. Fig. S2 show the loss of reactivity of Pt.9 CD8+ TIL to autologous cancer cell line by the 6th passage
Supplementary Table S8 from A Poor Prognosis Subtype of HNSCC Is Consistently Observed across Methylome, Transcriptome, and miRNome Analysis
Authors: Jung Alain C. , Job Sylvie , Ledrappier Sonia , Macabre Christine , Abecassis Joseph , de Reyniès Aurélien , Wasylyk Bohdan
Published: April 2023

Supplementary Table S8 - XLS file 10649K, This file contains the Supplementary Table S8. Table S8 lists the sensitivity and the specificity of individual probes to identify the R1 and non-�R1 groups
Supplementary Figure 4 from Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer
Authors: Cañadas Israel , Rojo Federico , Taus Álvaro , Arpí Oriol , Arumí-Uría Montserrat , Pijuan Lara , Menéndez Silvia , Zazo Sandra , Dómine Manuel , Salido Marta , Mojal Sergi , García de Herreros Antonio , Rovira Ana , Albanell Joan , Arriola Edurne
Published: April 2023

PDF file - 126K, PF-2341066 treatment upfront decreases tumorogenesis and local invasion in H69M xenograft.
Supplementary Figure 3 from Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer
Authors: Cañadas Israel , Rojo Federico , Taus Álvaro , Arpí Oriol , Arumí-Uría Montserrat , Pijuan Lara , Menéndez Silvia , Zazo Sandra , Dómine Manuel , Salido Marta , Mojal Sergi , García de Herreros Antonio , Rovira Ana , Albanell Joan , Arriola Edurne
Published: April 2023

PDF file - 163K, H69M2 are phenotypically mesenchymal and more tumorogenic.
Supplementary Table 2 from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Authors: Shapiro Geoffrey I. , Rodon Jordi , Bedell Cynthia , Kwak Eunice L. , Baselga Jose , Braña Irene , Pandya Shuchi S. , Scheffold Christian , Laird A. Douglas , Nguyen Linh T. , Xu Yi , Egile Coumaran , Edelman Gerald
Published: April 2023

PDF file - 63K, Reduction of PI3K pathway signaling in serial hair samples and skin biopsies.
Supplementary Table 1 from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Authors: Shapiro Geoffrey I. , Rodon Jordi , Bedell Cynthia , Kwak Eunice L. , Baselga Jose , Braña Irene , Pandya Shuchi S. , Scheffold Christian , Laird A. Douglas , Nguyen Linh T. , Xu Yi , Egile Coumaran , Edelman Gerald
Published: April 2023

PDF file - 73K, Safety of SAR245408.
Supplementary Figure S3 from Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008
Authors: Burvenich Ingrid J.G. , Lee Fook T. , Cartwright Glenn A. , O'Keefe Graeme J. , Makris Dahna , Cao Diana , Gong Sylvia , Chueh Anderly C. , Mariadason John M. , Brechbiel Martin W. , Beckman Robert A. , Fujiwara Kosaku , von Roemeling Reinhard , Scott Andrew M.
Published: April 2023

Supplementary Figure S3 - PDF file 489K, In vivo saturation of 111In-CHX-A"-DTPA-CS-1008 in WiDr tumors demonstrated by planar gamma camera imaging (A, 0.2 mg/kg; B, 0.5 mg/kg and C, 10 mg/kg). Representative whole body images (left), surface-rendered CT (middle) and fused images (right) are shown. Dorsal 20-minute images were collected
Supplementary Methods from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Authors: Shapiro Geoffrey I. , Rodon Jordi , Bedell Cynthia , Kwak Eunice L. , Baselga Jose , Braña Irene , Pandya Shuchi S. , Scheffold Christian , Laird A. Douglas , Nguyen Linh T. , Xu Yi , Egile Coumaran , Edelman Gerald
Published: April 2023

PDF file - 119K, Pharmacodynamic and Pharmacokinetic Assessment Methods.
Supplementary Figure 3 from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Authors: Shapiro Geoffrey I. , Rodon Jordi , Bedell Cynthia , Kwak Eunice L. , Baselga Jose , Braña Irene , Pandya Shuchi S. , Scheffold Christian , Laird A. Douglas , Nguyen Linh T. , Xu Yi , Egile Coumaran , Edelman Gerald
Published: April 2023

PDF file - 6224K, Inhibition of MEK-ERK pathway signaling in tumor biopsies.
Supplementary Figure 2 from Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Authors: Shapiro Geoffrey I. , Rodon Jordi , Bedell Cynthia , Kwak Eunice L. , Baselga Jose , Braña Irene , Pandya Shuchi S. , Scheffold Christian , Laird A. Douglas , Nguyen Linh T. , Xu Yi , Egile Coumaran , Edelman Gerald
Published: April 2023

PDF file - 1641K, Effect of SAR245408 on plasma fasting insulin and glucose.
Supplementary Table 3 from Characteristics of Lung Cancers Harboring NRAS Mutations
Authors: Ohashi Kadoaki , Sequist Lecia V. , Arcila Maria E. , Lovly Christine M. , Chen Xi , Rudin Charles M. , Moran Teresa , Camidge David Ross , Vnencak-Jones Cindy L. , Berry Lynne , Pan Yumei , Sasaki Hidefumi , Engelman Jeffrey A. , Garon Edward B. , Dubinett Steven M. , Franklin Wilbur A. , Riely Gregory J. , Sos Martin L. , Kris Mark G. , Dias-Santagata Dora , Ladanyi Marc , Bunn Paul A. , Pao William
Published: April 2023

PDF file - 65K, Supplemental Table 3. Characteristics of NRAS mutant lung cancer cell lines.
Supplementary Figures from A Collagen-Remodeling Gene Signature Regulated by TGF-β Signaling Is Associated with Metastasis and Poor Survival in Serous Ovarian Cancer
Authors: Cheon Dong-Joo , Tong Yunguang , Sim Myung-Shin , Dering Judy , Berel Dror , Cui Xiaojiang , Lester Jenny , Beach Jessica A. , Tighiouart Mourad , Walts Ann E. , Karlan Beth Y. , Orsulic Sandra
Published: April 2023

PDF file 831K, Supplementary Figures. Supplementary Fig. 1. A schematic diagram of the methods, datasets and patient samples used in this study. Supplementary Fig. 2. Correlogram of the 10 poor outcome. signature genes. Supplementary Fig. 3. Validation of the 10-gene signature - Kaplan-Meyer plot. Supplementary Fig. 4. Real-time PCR of poor outcome signature genes in normal, primary, and metastatic ovarian cancer samples. Supplementary Fig. 5. Increase in COL11A1 expression in recurrent tumors in comparison to primary ovarian tumors. Supplementary Fig. 6. Confinement of COL11A1 expression to intra- and peri-tumoral stroma - immunohistochemical detection. Supplementary Fig. 7. Knockdown of COL11A1 in the A2780 ovarian cancer cell line - qPCR and Western blot
Supplementary Methods from Randomized, Placebo-Controlled, Double-Blinded Chemoimmunotherapy Clinical Trial in a Pet Dog Model of Diffuse Large B-cell Lymphoma
Authors: Marconato Laura , Frayssinet Patrick , Rouquet Nicole , Comazzi Stefano , Leone Vito Ferdinando , Laganga Paola , Rossi Federica , Vignoli Massimo , Pezzoli Lorenzo , Aresu Luca
Published: April 2023

PDF file - 75K
Supplementary Table 1 from Characteristics of Lung Cancers Harboring NRAS Mutations
Authors: Ohashi Kadoaki , Sequist Lecia V. , Arcila Maria E. , Lovly Christine M. , Chen Xi , Rudin Charles M. , Moran Teresa , Camidge David Ross , Vnencak-Jones Cindy L. , Berry Lynne , Pan Yumei , Sasaki Hidefumi , Engelman Jeffrey A. , Garon Edward B. , Dubinett Steven M. , Franklin Wilbur A. , Riely Gregory J. , Sos Martin L. , Kris Mark G. , Dias-Santagata Dora , Ladanyi Marc , Bunn Paul A. , Pao William
Published: April 2023

PDF file - 72K, Supplemental Table 1. Histologies associated with NRAS mutant lung cancers from the COSMIC database.
Supplementary Figure 2 from Ketogenic Diets Enhance Oxidative Stress and Radio-Chemo-Therapy Responses in Lung Cancer Xenografts
Authors: Allen Bryan G. , Bhatia Sudershan K. , Buatti John M. , Brandt Kristin E. , Lindholm Kaleigh E. , Button Anna M. , Szweda Luke I. , Smith Brian J. , Spitz Douglas R. , Fath Melissa A.
Published: April 2023

Supplementary Figure 2 - PDF file 718K, Ketones and IR in vitro
Supplementary Figure 4 from Overexpression of the Circadian Clock Gene Bmal1 Increases Sensitivity to Oxaliplatin in Colorectal Cancer
Authors: Zeng Zhao-lei , Luo Hui-yan , Yang Jing , Wu Wen-jing , Chen Dong-liang , Huang Peng , Xu Rui-hua
Published: April 2023

PDF file 287K, Bmal1 overexpression increases apoptosis in HCT116 (A), THC8307 (B) and HT29 (C) cells after 48 h oxaliplatin treatment
Supplementary Figure 2 from Overexpression of the Circadian Clock Gene Bmal1 Increases Sensitivity to Oxaliplatin in Colorectal Cancer
Authors: Zeng Zhao-lei , Luo Hui-yan , Yang Jing , Wu Wen-jing , Chen Dong-liang , Huang Peng , Xu Rui-hua
Published: April 2023

PDF file 17K, Bmal1 protein expression in different CRC cell lines
Supplementary Figure Legends from Lack of Estrogen Receptor-α Is Associated with Epithelial–Mesenchymal Transition and PI3K Alterations in Endometrial Carcinoma
Authors: Wik Elisabeth , Ræder Maria B. , Krakstad Camilla , Trovik Jone , Birkeland Even , Hoivik Erling A. , Mjos Siv , Werner Henrica M.J. , Mannelqvist Monica , Stefansson Ingunn M. , Oyan Anne M. , Kalland Karl H. , Akslen Lars A. , Salvesen Helga B.
Published: April 2023

PDF file - 60 KB
Supplementary Figure 4 from TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance
Authors: Silwal-Pandit Laxmi , Vollan Hans Kristian Moen , Chin Suet-Feung , Rueda Oscar M. , McKinney Steven , Osako Tomo , Quigley David A. , Kristensen Vessela N. , Aparicio Samuel , Børresen-Dale Anne-Lise , Caldas Carlos , Langerød Anita
Published: April 2023

PDF file - 22KB, Figure S4. Distribution of TP53 mutations in IC subtypes. A. METABRIC cohort. B. TCGA cohort.
Supplementary Figure 3 from TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance
Authors: Silwal-Pandit Laxmi , Vollan Hans Kristian Moen , Chin Suet-Feung , Rueda Oscar M. , McKinney Steven , Osako Tomo , Quigley David A. , Kristensen Vessela N. , Aparicio Samuel , Børresen-Dale Anne-Lise , Caldas Carlos , Langerød Anita
Published: April 2023

PDF file - 264KB, Figure S3. A. Distribution of TP53 mutation, LOH, mRNA and protein expression in IC and PAM50 subtypes. B. Boxplot diagram showing the TP53 mRNA expression levels (log intensity values) with respect to TP53 protein expression (percentage of IHC staining) in mutated and wildtype tumors, and with respect to mutation types. The bold black line represents the mean TP53 expression value and the box represents 25th and 75th percentiles.
Supplementary Table 1 from Quantification of Excision Repair Cross-Complementing Group 1 and Survival in p16-Negative Squamous Cell Head and Neck Cancers
Authors: Mehra Ranee , Zhu Fang , Yang Dong-Hua , Cai Kathy Q. , Weaver JoEllen , Singh Mahendra K. , Nikonova Anna S. , Golemis Erica A. , Flieder Douglas B. , Cooper Harry S. , Lango Miriam , Ridge John A. , Burtness Barbara
Published: April 2023

PDF file - 78K, Characteristics of recurrent cases.
Supplementary Table 2 from Tumor Growth Rate Is an Early Indicator of Antitumor Drug Activity in Phase I Clinical Trials
Authors: Ferté Charles , Fernandez Marianna , Hollebecque Antoine , Koscielny Serge , Levy Antonin , Massard Christophe , Balheda Rastislav , Bot Brian , Gomez-Roca Carlos , Dromain Clarisse , Ammari Samy , Soria Jean-Charles
Published: April 2023

XLS file 27K, Distribution of the tumor response (RECIST) according to the decrease of TGR between the REFERENCE and the EXPERIMENTAL periods
Supplementary Figures 1 - 2 from Quantification of Excision Repair Cross-Complementing Group 1 and Survival in p16-Negative Squamous Cell Head and Neck Cancers
Authors: Mehra Ranee , Zhu Fang , Yang Dong-Hua , Cai Kathy Q. , Weaver JoEllen , Singh Mahendra K. , Nikonova Anna S. , Golemis Erica A. , Flieder Douglas B. , Cooper Harry S. , Lango Miriam , Ridge John A. , Burtness Barbara
Published: April 2023

PDF file - 194K, Supplemental Figure S1. A. Immunofluorescence staining: ERCC1 antibody of Sigma HPA029773 (upper row) and Lab Vision 8F1 (middle row) showed clear nuclear staining. Both cytoplasmic and nuclear staining of ERCC1 was seen using Santa Cruz FL297 (lower row), resulting in a more diffuse staining pattern. B. Correlation coefficient between AQUA and H scores for 8F1 staining, 0.69. Scores are read for each spot (plotted on X and Y axis). Supplemental Figure S2. ERCC1 expression using the antibody HPA029773 was localized in the nucleus of non-keratinizing (A) and keratinizing (B) squamous cell carcinoma (SCC). Upper panel: high ERCC1 AQUA score. Lower panel: low ERCC1 AQUA score. Note the staining intensity of cytokeratin and the nuclear stain DAPI are the same in all specimens.
Supplementary Table 1 from Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer
Authors: Sewell Andrew , Brown Brandee , Biktasova Asel , Mills Gordon B. , Lu Yiling , Tyson Darren R. , Issaeva Natalia , Yarbrough Wendell G.
Published: April 2023

PDF file - 37KB, Differentially expressed proteins in HPV(+) vs HPV(-) OPSCC (0.05
Supplementary Figure 1 from LINE-1 Hypomethylation, DNA Copy Number Alterations, and CDK6 Amplification in Esophageal Squamous Cell Carcinoma
Authors: Baba Yoshifumi , Watanabe Masayuki , Murata Asuka , Shigaki Hironobu , Miyake Keisuke , Ishimoto Takatsugu , Iwatsuki Masaaki , Iwagami Shiro , Yoshida Naoya , Oki Eiji , Sakamaki Kentaro , Nakao Mitsuyoshi , Baba Hideo
Published: April 2023

PDF file - 195K, The result of CGH arrays in 6 cases.
Supplementary Figure 7 from A Tumorigenic Factor Interactome Connected through Tumor Suppressor MicroRNA-198 in Human Pancreatic Cancer
Authors: Marin-Muller Christian , Li Dali , Bharadwaj Uddalak , Li Min , Chen Changyi , Hodges Sally E. , Fisher William E. , Mo Qianxing , Hung Mien-Chie , Yao Qizhi
Published: April 2023

Supplementary Figure 7 - PDF file 166K, Real-time RT-PCR shows the mRNA levels of all the factors in the proposed network and Linear regression analyses depict the correlations between each factor and its counterparts
Supplementary Figure 4 from A Tumorigenic Factor Interactome Connected through Tumor Suppressor MicroRNA-198 in Human Pancreatic Cancer
Authors: Marin-Muller Christian , Li Dali , Bharadwaj Uddalak , Li Min , Chen Changyi , Hodges Sally E. , Fisher William E. , Mo Qianxing , Hung Mien-Chie , Yao Qizhi
Published: April 2023

Supplementary Figure 4 - PDF file 269K, Additional evidence that miR-198 targets the PBX-1/VCP axis
Supplementary Figure 1 from Mesothelin Overexpression Is a Marker of Tumor Aggressiveness and Is Associated with Reduced Recurrence-Free and Overall Survival in Early-Stage Lung Adenocarcinoma
Authors: Kachala Stefan S. , Bograd Adam J. , Villena-Vargas Jonathan , Suzuki Kei , Servais Elliot L. , Kadota Kyuichi , Chou Joanne , Sima Camelia S. , Vertes Eva , Rusch Valerie W. , Travis William D. , Sadelain Michel , Adusumilli Prasad S.
Published: April 2023

PDF file - 110K, Supplementary Fig. S1. Mesothelin (MSLN) immunohistochemical analysis demonstrating membranous and cytoplasmic staining.
Supplementary Table 7 - 8 from Identification of Campath-1 (CD52) as Novel Drug Target in Neoplastic Stem Cells in 5q-Patients with MDS and AML
Authors: Blatt Katharina , Herrmann Harald , Hoermann Gregor , Willmann Michael , Cerny-Reiterer Sabine , Sadovnik Irina , Herndlhofer Susanne , Streubel Berthold , Rabitsch Werner , Sperr Wolfgang R. , Mayerhofer Matthias , Rülicke Thomas , Valent Peter
Published: April 2023

PDF file - 88K, Supplementary Table S7: Expression of the surface antigen CD52 on CD34+/CD38− cells and CD34+/CD38+ cells in CML, CMML, MDS/MPN-U, MPN, AUL, and ALL Supplementary Table S8: Expression of CD52 on CD34+/CD38− cells, CD34+/CD38+ cells, monocytes, and blood basophils in patients with ICUS, normal/reactive bone marrow, and complete long-term remission after AML.
Supplementary Table S2 from The Activation of the WNT Signaling Pathway Is a Hallmark in Neurofibromatosis Type 1 Tumorigenesis
Authors: Luscan Armelle , Shackleford Ghjuvan'Ghjacumu , Masliah-Planchon Julien , Laurendeau Ingrid , Ortonne Nicolas , Varin Jennifer , Lallemand François , Leroy Karen , Dumaine Valérie , Hivelin Mikael , Borderie Didier , De Raedt Thomas , Valeyrie-Allanore Laurence , Larousserie Frédérique , Terris Benoît , Lantieri Laurent , Vidaud Michel , Vidaud Dominique , Wolkenstein Pierre , Parfait Béatrice , Bièche Ivan , Massaad Charbel , Pasmant Eric
Published: April 2023

PDF file 97K, List of the 89 Wnt pathway selected genes
Supplementary Table S1 from The Activation of the WNT Signaling Pathway Is a Hallmark in Neurofibromatosis Type 1 Tumorigenesis
Authors: Luscan Armelle , Shackleford Ghjuvan'Ghjacumu , Masliah-Planchon Julien , Laurendeau Ingrid , Ortonne Nicolas , Varin Jennifer , Lallemand François , Leroy Karen , Dumaine Valérie , Hivelin Mikael , Borderie Didier , De Raedt Thomas , Valeyrie-Allanore Laurence , Larousserie Frédérique , Terris Benoît , Lantieri Laurent , Vidaud Michel , Vidaud Dominique , Wolkenstein Pierre , Parfait Béatrice , Bièche Ivan , Massaad Charbel , Pasmant Eric
Published: April 2023

PDF file 55K, Clinical and histological characteristics of the 16 patients with MPNSTs
Supplementary Figure 8 from Downregulation of miR-138 Sustains NF-κB Activation and Promotes Lipid Raft Formation in Esophageal Squamous Cell Carcinoma
Authors: Gong Hui , Song Libing , Lin Chuyong , Liu Aibin , Lin Xi , Wu Jueheng , Li Mengfeng , Li Jun
Published: April 2023

PDF file - 43 KB, FLOT1, FLOT2 and caveolin-1 were functional effectors of miR-138 on regulating NF-�B activation.
Supplementary Figures from Targeted Imaging of Ewing Sarcoma in Preclinical Models Using a 64Cu-Labeled Anti-CD99 Antibody
Authors: O'Neill Allison F. , Dearling Jason L.J. , Wang Yuchuan , Tupper Tanya , Sun Yanping , Aster Jon C. , Calicchio Monica L. , Perez-Atayde Antonio R. , Packard Alan B. , Kung Andrew L.
Published: April 2023

PDF file 373K, Supplementary Figure 1: Staining of additional Ewing sarcoma cell lines. Supplementary Figure 2: MRI detection of experimental metastases
Supplementary Figure 1 from Human Breast Cancer Cells Harboring a Gatekeeper T798M Mutation in HER2 Overexpress EGFR Ligands and Are Sensitive to Dual Inhibition of EGFR and HER2
Authors: Rexer Brent N. , Ghosh Ritwik , Narasanna Archana , Estrada Mónica Valeria , Chakrabarty Anindita , Song Youngchul , Engelman Jeffrey A. , Arteaga Carlos L.
Published: April 2023

Supplementary Figure 1 - PDF file 189K, Pan-ErbB inhibitor CI-1033 inhibits HER2 phosphorylation and cell growth of both wild-type and T798M mutant cells
Supplementary Table 1 from mTORC1 Inhibitors Suppress Meningioma Growth in Mouse Models
Authors: Pachow Doreen , Andrae Nadine , Kliese Nadine , Angenstein Frank , Stork Oliver , Wilisch-Neumann Annette , Kirches Elmar , Mawrin Christian
Published: April 2023

PDF file - 65K, Effect of temsirolimus in a subcutaneous xenograft mouse model
Supplementary Tables 1-6 from Distinction between Asymptomatic Monoclonal B-cell Lymphocytosis with Cyclin D1 Overexpression and Mantle Cell Lymphoma: From Molecular Profiling to Flow Cytometry
Authors: Espinet Blanca , Ferrer Ana , Bellosillo Beatriz , Nonell Lara , Salar Antonio , Fernández-Rodríguez Concepción , Puigdecanet Eulàlia , Gimeno Javier , Garcia-Garcia Mar , Vela Maria Carmen , Luño Elisa , Collado Rosa , Navarro José Tomás , de la Banda Esmeralda , Abrisqueta Pau , Arenillas Leonor , Serrano Cristina , Lloreta Josep , Miñana Belén , Cerutti Andrea , Florensa Lourdes , Orfao Alberto , Sanz Ferran , Solé Francesc , Dominguez-Sola David , Serrano Sergio
Published: April 2023

PDF file 233K, SupplementaryTable S1. Detailed clinical and pathological features of all the cases included in the study; S2. Detailed flow cytometric, cytogenetic and molecular findings of all the cases included in the study; S3. Sequence analysis of the MTC PCR products encompassing the IGH/CCND1 junction; S4. List of differentially expressed genes between MCL and MALD1 with order of appearance in Figure 4C; S5. Summary of the main pathways differentially enriched in MALD1 and MCL lymphocytes; S6. Table of all samplesused to generatethe CART. Classification column presents the assigned group after applying the CART
Supplementary Figure 1 from Lung Cancers with Concomitant EGFR Mutations and ALK Rearrangements: Diverse Responses to EGFR-TKI and Crizotinib in Relation to Diverse Receptors Phosphorylation
Authors: Yang Jin-Ji , Zhang Xu-Chao , Su Jian , Xu Chong-Rui , Zhou Qing , Tian Hong-Xia , Xie Zhi , Chen Hua-Jun , Huang Yi-Sheng , Jiang Ben-Yuan , Wang Zhen , Wang Bin-Chao , Yang Xue-Ning , Zhong Wen-Zhao , Nie Qiang , Liao Ri-Qiang , Mok Tony S. , Wu Yi-Long
Published: April 2023

PDF file - 635KB, Sequence results of EML4-ALK fusion variants.
Supplementary Figure 2 from Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth
Authors: Grohar Patrick J. , Segars Laure E. , Yeung Choh , Pommier Yves , D'Incalci Maurizio , Mendoza Arnulfo , Helman Lee J.
Published: April 2023

PDF file 74K, Growth curves showing mean tumor volume for cohorts of mice with the TC71 (top) and TC32 (bottom) xenografts for vehicle control (blue), trabectedin treatment (ET-743; Red), irinotecan (green) and trabectedin plus irinotecan (combination, purple). Arrows highlight days of treatment
Supplementary Figure 1 from Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth
Authors: Grohar Patrick J. , Segars Laure E. , Yeung Choh , Pommier Yves , D'Incalci Maurizio , Mendoza Arnulfo , Helman Lee J.
Published: April 2023

PDF file 31K, Expression profiling showing suppression of WRN and XRCC4 with trabectedin treatment. Green represents suppression and Red induction in expression
Supplementary Table S1 from Inhibition of Tumor Growth and Metastasis in Non–Small Cell Lung Cancer by LY2801653, an Inhibitor of Several Oncokinases, Including MET
Authors: Wu Wenjuan , Bi Chen , Credille Kelly M. , Manro Jason R. , Peek Victoria L. , Donoho Gregory P. , Yan Lei , Wijsman John A. , Yan S. Betty , Walgren Richard A.
Published: April 2023

Supplementary Table S1 - PDF file 76K, MET expression by immunohistochemistry
Supplementary Materials and Methods from Inhibition of Tumor Growth and Metastasis in Non–Small Cell Lung Cancer by LY2801653, an Inhibitor of Several Oncokinases, Including MET
Authors: Wu Wenjuan , Bi Chen , Credille Kelly M. , Manro Jason R. , Peek Victoria L. , Donoho Gregory P. , Yan Lei , Wijsman John A. , Yan S. Betty , Walgren Richard A.
Published: April 2023

Supplementary Materials and Methods - PDF file 109K, 1.Evaluation of LY2801653 antitumor effect in human lung cancer cell lines and patient-derived tumor (PDT) derived xenograft models. 2.Histology and immunohistochemistry 3.Statistical analysis
Fig. S8 from The Disparate Twins: A Comparative Study of CXCR4 and CXCR7 in SDF-1α–Induced Gene Expression, Invasion and Chemosensitivity of Colon Cancer
Authors: Heckmann Doreen , Maier Patrick , Laufs Stephanie , Li Li , Sleeman Jonathan P. , Trunk Marcus J. , Leupold Jörg H. , Wenz Frederik , Zeller W. Jens , Fruehauf Stefan , Allgayer Heike
Published: April 2023

PDF file 53K, S8: Percentage of chemokine receptor surface expression after SDF-1a treatment
Supplementary Figure 2 from Zoledronic Acid Has Differential Antitumor Activity in the Pre- and Postmenopausal Bone Microenvironment In Vivo
Authors: Ottewell Penelope D. , Wang Ning , Brown Hannah K. , Reeves Kimberly J. , Fowles C. Anne , Croucher Peter I. , Eaton Colby L. , Holen Ingunn
Published: April 2023

PDF file - 50KB, Numbers of MDA-MB-231 cells present in long bones of 12 week old mice 24h after inter-cardiac injection.
Supplementary Figure 1 from Zoledronic Acid Has Differential Antitumor Activity in the Pre- and Postmenopausal Bone Microenvironment In Vivo
Authors: Ottewell Penelope D. , Wang Ning , Brown Hannah K. , Reeves Kimberly J. , Fowles C. Anne , Croucher Peter I. , Eaton Colby L. , Holen Ingunn
Published: April 2023

PDF file - 1125KB, MDA-MB-231 tumour growth in 6 week and 12 week old Balb/c nude mice 4 weeks following intra-cardiac injection.
Fig. S3 from The Disparate Twins: A Comparative Study of CXCR4 and CXCR7 in SDF-1α–Induced Gene Expression, Invasion and Chemosensitivity of Colon Cancer
Authors: Heckmann Doreen , Maier Patrick , Laufs Stephanie , Li Li , Sleeman Jonathan P. , Trunk Marcus J. , Leupold Jörg H. , Wenz Frederik , Zeller W. Jens , Fruehauf Stefan , Allgayer Heike
Published: April 2023

PDF file 79K, S3: Effect of SDF-1a on expression of EGFR
Supplementary Figure 2 from Prognostic and Therapeutic Implications of Aromatase Expression in Lung Adenocarcinomas with EGFR Mutations
Authors: Kohno Mikihiro , Okamoto Tatsuro , Suda Kenichi , Shimokawa Mototsugu , Kitahara Hirokazu , Shimamatsu Shinichiro , Konishi Hideyuki , Yoshida Tsukihisa , Takenoyama Mitsuhiro , Yano Tokujiro , Maehara Yoshihiko
Published: April 2023

PDF file - 102KB, Supplementary figure S2. Effect of exemestane on wild-type EGFR and high-aromatase mRNA-expressing lung adenocarcinoma cell line proliferation.
CCR Translation for This Article from The Ubiquitin–CXCR4 Axis Plays an Important Role in Acute Lung Infection–Enhanced Lung Tumor Metastasis
Authors: Yan Libo , Cai Qingchun , Xu Yan
Published: April 2023

CCR Translation for This Article from The Ubiquitin–CXCR4 Axis Plays an Important Role in Acute Lung Infection–Enhanced Lung Tumor Metastasis