Pulsed Voltammetry of an Aspidosperma Alakaloid: Vindoline
Authors: Haque Inam ul , Tariq Muqaddas , Aslam Nishat , Saba Hina 
Published: May 2020

There is steady interest in the chemistry surrounding vindoline [1] and its uses [2]. Of interest are the number of electron(s) involved in the electro-oxidation of its tertiary amine nitrogen and the dihydro-indole nitrogen. Normal pulse voltammetry (NPV) showed two successive one-electron removals respectively from the two nitrogens; essentially in conformity with reported work [3] based on a different technique.

The second electron transfer likely is not reversible as reverse normal pulse voltammetry (RNPV) revealed no first current plateau [4] irrespective of the initial potential(s) selected from the second plateau of the normal pulse voltammogram. On the other hand, anodic cyclic voltammetry of vindoline [5] appears to indicate the formation of its dimers [5, 6] and trimers [7, 8].

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