bluuebunny/crossref_metadata_2025 huggingface dataset:
Scaled weighted total least-squares adjustment
for partial errors-in-variables model
Authors: Zhao J.
Published: December 2016

Scaled total least-squares (STLS) unify LS, Data
LS, and TLS with a different choice of scaled parameter.
The function of the scaled parameter is to balance the
effect of random error of coefficient matrix and observation
vector for the estimate of unknown parameter. Unfortunately,
there are no discussions about how to determine
the scaled parameter. Consequently, the STLS solution
cannot be obtained because the scaled parameter is
unknown. In addition, the STLS method cannot be applied
to the structured EIV casewhere the coefficient matrix contains
the fixed element and the repeated random elements
in different locations or both. To circumvent the shortcomings
above, the study generalize it to a scaledweighted TLS
(SWTLS) problem based on partial errors-in-variable (EIV)
model. And the maximum likelihood method is employed
to derive the variance component of observations and coefficient
matrix. Then the ratio of variance component is
proposed to get the scaled parameter. The existing STLS
method and WTLS method is just a special example of the
SWTLS method. The numerical results show that the proposed
method proves to bemore effective in some aspects.
“In loco qui dicitur Galca”. New Observations and Hypotheses on the Norman Palace in Palermo
Authors: Longo Ruggero
Published: December 2016

This paper presents the results of an intensive study of both historical sources and literature concerning the Royal Palace in Palermo. The study of this architectural palimpsest deals with the intrinsic difficulty in distinguishing continuity and discontinuity across a stratified overlap of medieval phases, here defined as a mimetic phase of transition. The paper aims to trace the development of the building from the Norman conquest to the establishment of the kingdom, also taking into account a possible pre-Norman phase and the transformations which occurred in the Early Modern period. Issues concerning the construction of the first Palatine Chapel are also addressed, which leads to the individuation of hidden layers of the Palace. The final part of the paper focuses on one of the most important Norman portions of the Palace: the Torre Pisana. The analysis of its medieval structure reveals its Islamic features and opens new hypotheses on its original function and configuration.
Nanoscale Thermal Transfer – An Invitation to Fluctuation Electrodynamics
Authors: Henkel Carsten
Published: December 2016

An electromagnetic theory of thermal radiation is outlined, based on the fluctuation electrodynamics of Rytov and co-workers. We discuss the basic concepts and the status of different approximations. The physical content is illustrated with a few examples on near-field heat transfer.
Spatial Organization of Chromatic Pathways in the Mouse Dorsal Lateral Geniculate Nucleus
Authors: Denman Daniel J. , Siegle Joshua H. , Koch Christof , Reid R. Clay , Blanche Timothy J.
Published: December 2016

In both dichromats and trichromats, cone opsin signals are maintained independently in cones and combined at the bipolar and retinal ganglion cell level, creating parallel color opponent pathways to the central visual system. Like other dichromats, the mouse retina expresses a short-wavelength (S) and a medium-wavelength (M) opsin, with the S-opsin shifted to peak sensitivity in the ultraviolet (UV) range. Unlike in primates, nonuniform opsin expression across the retina and coexpression in single cones creates a mostly mixed chromatic signal. Here, we describe the visuotopic and chromatic organization of spiking responses in the dorsal lateral geniculate and of the local field potentials in their recipient zone in primary visual cortex (V1). We used an immersive visual stimulus dome that allowed us to present spatiotemporally modulated UV and green luminance in any region of the visual field of an awake, head-fixed mouse. Consistent with retinal expression of opsins, we observed graded UV-to-green dominated responses from the upper to lower visual fields, with a smaller difference across azimuth. In addition, we identified a subpopulation of cells (<10%) that exhibited spectrally opponent responses along the S–M axis. Luminance signals of each wavelength and color signals project to the middle layers of V1.

SIGNIFICANCE STATEMENTIn natural environments, color information is useful for guiding behavior. How small terrestrial mammals such as mice use graded expression of cone opsins to extract visual information from their environments is not clear, even as the use of mice for studying visually guided behavior grows. In this study, we examined the color signals that the retina sends to the visual cortex via the lateral geniculate nucleus of the thalamus. We found that green dominated responses in the lower and nasal visual field and ultraviolet dominated responses in the upper visual field. We describe a subset of cells that exhibit color opponent responses.
Nonlinear Y-Like Receptive Fields in the Early Visual Cortex: An Intermediate Stage for Building Cue-Invariant Receptive Fields from Subcortical Y Cells
Authors: Gharat Amol , Baker Curtis L.
Published: December 2016

Many of the neurons in early visual cortex are selective for the orientation of boundaries defined by first-order cues (luminance) as well as second-order cues (contrast, texture). The neural circuit mechanism underlying this selectivity is still unclear, but some studies have proposed that it emerges from spatial nonlinearities of subcortical Y cells. To understand how inputs from the Y-cell pathway might be pooled to generate cue-invariant receptive fields, we recorded visual responses from single neurons in cat Area 18 using linear multielectrode arrays. We measured responses to drifting and contrast-reversing luminance gratings as well as contrast modulation gratings. We found that a large fraction of these neurons have nonoriented responses to gratings, similar to those of subcortical Y cells: they respond at the second harmonic (F2) to high-spatial frequency contrast-reversing gratings and at the first harmonic (F1) to low-spatial frequency drifting gratings (“Y-cell signature”). For a given neuron, spatial frequency tuning for linear (F1) and nonlinear (F2) responses is quite distinct, similar to orientation-selective cue-invariant neurons. Also, these neurons respond to contrast modulation gratings with selectivity for the carrier (texture) spatial frequency and, in some cases, orientation. Their receptive field properties suggest that they could serve as building blocks for orientation-selective cue-invariant neurons. We propose a circuit model that combines ON- and OFF-center cortical Y-like cells in an unbalanced push–pull manner to generate orientation-selective, cue-invariant receptive fields.

SIGNIFICANCE STATEMENTA significant fraction of neurons in early visual cortex have specialized receptive fields that allow them to selectively respond to the orientation of boundaries that are invariant to the cue (luminance, contrast, texture, motion) that defines them. However, the neural mechanism to construct such versatile receptive fields remains unclear. Using multielectrode recording, we found a large fraction of neurons in early visual cortex with receptive fields not selective for orientation that have spatial nonlinearities like those of subcortical Y cells. These are strong candidates for building cue-invariant orientation-selective neurons; we present a neural circuit model that pools such neurons in an imbalanced “push–pull” manner, to generate orientation-selective cue-invariant receptive fields.
Infundibulo-hypophysitis-like radiological image in a patient with pituitary infiltration of a diffuse large B-cell non-Hodgkin lymphoma
Authors: León-Suárez A , Roldán-Sarmiento P , Gómez-Sámano M A , Nava-De la Vega A , Enríquez-Estrada V M , Gómez-Pérez F J , Cuevas-Ramos D
Published: December 2016

Non-Hodgkin lymphoma (NHL) is a hematological tumor caused by abnormal lymphoid proliferation. NHL can arise in any part of the body, including central nervous system (CNS). However, pituitary involvement is a quite rare presentation. The diffuse large B-cell lymphoma (DLBCL) is the most common subtype when pituitary is infiltrated. Here, we report a case of pituitary infiltration of NHL DLBCL type in a woman with hypopituitarism and an infundibulum-hypophysitis-like image on magnetic resonance imaging (MRI). A female aged 64 years, complained of dyspepsia, fatigue, weight loss and urine volume increment with thirst. Endoscopy and gastric biopsy confirmed diffuse large B-cell lymphoma. Treatment with chemotherapy using R-CHOP was initiated. During her hospitalization, hypotension and polyuria were confirmed. Hormonal evaluation was compatible with central diabetes insipidus and hypopituitarism. Simple T1 sequence of MRI showed thickening of the infundibular stalk with homogeneous enhancement. After lumbar puncture analysis, CNS infiltration was confirmed showing positive atypical lymphocytes. Pituitary and infundibular stalk size normalized after R-CHOP chemotherapy treatment. In conclusion, pituitary infiltration of NHL with infundibular-hypophysitis-like image on MRI is a rare finding. Clinical picture included hypopituitarism and central diabetes insipidus. Diagnosis should be suspected after biochemical analysis and MRI results. Treatment consists of chemotherapy against NHL and hormonal replacement for pituitary dysfunction.

Learning points:

Pituitary infiltration by lymphoma can present with signs and symptoms of panhypopituitarism and diabetes insipidus.

MRI findings can resemble an autoimmune hypophysitis.

Patients can recover pituitary function as well as normalization of MRI after chemotherapy treatment.
Dwarfism and Altered Craniofacial Development in Rabbits Is Caused by a 12.1 kb Deletion at the HMGA2 Locus
Authors: Carneiro Miguel , Hu Dou , Archer John , Feng Chungang , Afonso Sandra , Chen Congying , Blanco-Aguiar José A , Garreau Hervé , Boucher Samuel , Ferreira Paula G , Ferrand Nuno , Rubin Carl-Johan , Andersson Leif
Published: December 2016

The dwarf phenotype characterizes the smallest of rabbit breeds and is governed largely by the effects of a single dwarfing allele with an incompletely dominant effect on growth. Dwarf rabbits typically weigh under 1 kg and have altered craniofacial morphology. The dwarf allele is recessive lethal and dwarf homozygotes die within a few days of birth. The dwarf phenotype is expressed in heterozygous individuals and rabbits from dwarf breeds homozygous for the wild-type allele are normal, although smaller when compared to other breeds. Here, we show that the dwarf allele constitutes a ∼12.1 kb deletion overlapping the promoter region and first three exons of the HMGA2 gene leading to inactivation of this gene. HMGA2 has been frequently associated with variation in body size across species. Homozygotes for null alleles are viable in mice but not in rabbits and probably not in humans. RNA-sequencing analysis of rabbit embryos showed that very few genes (4–29 genes) were differentially expressed among the three HMGA2/dwarf genotypes, suggesting that dwarfism and inviability in rabbits are caused by modest changes in gene expression. Our results show that HMGA2 is critical for normal expression of IGF2BP2, which encodes an RNA-binding protein. Finally, we report a catalog of regions of elevated genetic differentiation between dwarf and normal-size rabbits, including LCORL-NCAPG, STC2, HOXD cluster, and IGF2BP2. Levels and patterns of genetic diversity at the LCORL-NCAPG locus further suggest that small size in dwarf breeds was enhanced by crosses with wild rabbits. Overall, our results imply that small size in dwarf rabbits results from a large effect, loss-of-function (LOF) mutation in HMGA2 combined with polygenic selection.
Repair of Meiotic DNA Breaks and Homolog Pairing in Mouse Meiosis Requires a Minichromosome Maintenance (MCM) Paralog
Authors: McNairn Adrian J , Rinaldi Vera D , Schimenti John C
Published: December 2016

The mammalian Mcm-domain containing 2 (Mcmdc2) gene encodes a protein of unknown function that is homologous to the minichromosome maintenance family of DNA replication licensing and helicase factors. Drosophila melanogaster contains two separate genes, the Mei-MCMs, which appear to have arisen from a single ancestral Mcmdc2 gene. The Mei-MCMs are involved in promoting meiotic crossovers by blocking the anticrossover activity of BLM helicase, a function presumably performed by MSH4 and MSH5 in metazoans. Here, we report that MCMDC2-deficient mice of both sexes are viable but sterile. Males fail to produce spermatozoa, and formation of primordial follicles is disrupted in females. Histology and immunocytological analyses of mutant testes revealed that meiosis is arrested in prophase I, and is characterized by persistent meiotic double-stranded DNA breaks (DSBs), failure of homologous chromosome synapsis and XY body formation, and an absence of crossing over. These phenotypes resembled those of MSH4/5-deficient meiocytes. The data indicate that MCMDC2 is essential for invasion of homologous sequences by RAD51- and DMC1-coated single-stranded DNA filaments, or stabilization of recombination intermediates following strand invasion, both of which are needed to drive stable homolog pairing and DSB repair via recombination in mice.
Metabolikus sebészeti tevékenységünk, 2010–2016
Authors: Mohos Elemér , Nagy Attila , Szabados György , Szabó Lóránt , Szabó László , Gál Béla , Kiss Miklós , Réti György , Kovács Tamás , Jánó Zoltán , Berki Csaba , Mohay József , Bene Krisztina , Bognár Gábor , Horzov Myroslav , Mohos Petra , Sándor Gábor , Tornai Gábor , Szenkovits Péter , Nagy Tibor , Orbán Csaba , Herpai Vivien
Published: December 2016

Absztrakt

Bevezetés: A kóros elhízás és az okozott társbetegségek,
elsősorban a 2-es típusú diabetes prevalenciája az elmúlt évtizedekben rohamos
növekedésnek indult. Miután a konzervatív kezelési módszerek (diéta, tréning)
legtöbbször nem hoznak megoldást, egyre nagyobb az igény a metabolikus sebészeti
beavatkozásokra. Módszer: Osztályunkon az elmúlt hat és fél
évben 514 laparoszkópos Roux Y gyomorbypassműtétet (LRYGB) és 54 laparoszkópos
gyomorsleeve-reszekciót (LGSR) végeztünk. Random kiválasztott 40,
gyomorbypassműtéten és 15 sleeve-reszekción átesett beteg adatait dolgoztuk fel.
Ismertetésre kerülnek az alkalmazott indikációs kritériumok, a pre- és
posztoperatív rutineljárások, az elért eredmények, illetve a komplikációk típusa
és aránya. Eredmények: Tapasztalataink alapján mindkét műtéti
beavatkozás relatív alacsony szövődményráta mellett végezhető és hosszú távon is
hatékony mind a testsúlycsökkenés, mind a társbetegségek javulásának
vonatkozásában. Gyomorbypass után nagyobb mértékű fogyást
(testsúlyfelesleg-csökkenés 88% vs. 68%) és a 2-es típusú diabetes, a hypertonia
és a gastrooesophagealis reflux magasabb arányú javulását tapasztaltuk a
sleeve-reszekcióhoz viszonyítva. Konklúzió: Eredményeink
alapján az LRYGB-t részesítjük előnyben, sleeve-reszekciót akkor indikálunk,
amikor bypass végzésére nincs, illetve csak magas rizikó mellett volna
lehetőség, természetesen figyelembe véve a beteg ez irányú, egyénre szabott
igényeit is.
National Innovation System and external constraint on growth
Authors: Resende Marco Flávio da Cunha , Torres Daniela Almeida Raposo
Published: December 2016

ABSTRACT Segundo a literatura sobre modelos de crescimento com restrição externa, as diferenças nas elasticidades-renda da demanda de importações e de exportações entre os países levam a diferentes graus de restrição externa ao crescimento dos mesmos. Contudo, não há nesta literatura uma explicação que utiliza o conceito Evolucionário de Sistema Nacional de Inovações (SI) para mostrar o motivo para as diferenças nas elasticidades-renda dos países. Ademais, não há um consenso sobre a exogeneidade destas elasticidades. Alguns autores enfatizam que a elasticidade-renda de exportações é maior nos setores com maior intensidade tecnológica. Porém, estes autores não explicam os motivos para isto ocorrer. Neste artigo visa-se mostrar teoricamente a relação de causalidade entre o SI de uma economia, suas elasticidades-renda e seu desempenho em transações correntes. Objetiva--se, também, mostrar o papel do SI na determinação da exogeneidade/endogeneidade das elasticidades. A evidência empírica apresentada neste estudo não rejeita seus argumentos.
A ADMINISTRAÇÃO DO TEMPO LIVRE
Authors: Musse Ricardo
Published: December 2016

Resumo A conferência de Theodor W. Adorno sobre o conceito e a prática do "tempo livre", publicada em Stichworte, em 1969, foi proferida numa época de pleno emprego. A gradativa redução da jornada normal de trabalho, sinalizando e consolidando uma tendência de longo prazo, inspirou uma série de conjecturas acerca de uma possível mudança nas estruturas até então assentadas como próprias do mundo moderno. Nesse contexto, a conferência-ensaio de Adorno organiza-se, ao mesmo tempo, como uma atualização e como um comentário das considerações de Karl Marx sobre a situação do trabalho no capitalismo. Remete também, ainda que em menor medida, às ponderações de Max Weber que se tornaram um dos pomos de discórdia na controvérsia a respeito da obsolescência ou não do paradigma da "sociedade do trabalho.
AÇÃO AFIRMATIVA NO BRASIL: MULTICULTURALISMO OU JUSTIÇA SOCIAL?
Authors: Feres Júnior João , Campos Luiz Augusto
Published: December 2016

Resumo O presente artigo pretende responder se as políticas de ação afirmativa racial hoje adotadas no Brasil se encaixam no modelo de políticas multiculturais da maneira como as concebe Will Kymlicka. A questão se justifica para além do interesse teórico, porque elas foram tomadas como uma importação do multiculturalismo anglo-saxão pelos detratores da ação afirmativa. Para tal, emprestamos o conceito de cultura societal, formulado por Kymlicka, e examinamos como a ação afirmativa opera em relação a ele. Em seguida, examinamos os argumentos acerca dessas políticas em vários âmbitos de debate e deliberação (Constituição de 1988, Governo Federal, STF, Programas de Cotas de universidades públicas e jornalismo), para mostrar que a ação afirmativa no Brasil está longe de ser uma política típica do multiculturalismo, ou seja, do reconhecimento da diferença cultural. Há traços aqui e ali de argumentos multiculturalistas na Constituição, no debate público e mesmo na decisão do STF, mas a lógica principal que vigora é a da justiça social, nos termos de um liberalismo igualitário.
INDÍCIOS DE AUTORIA NA PRODUÇÃO DE RESENHAS DE ESTUDANTES DE ENSINO MÉDIO
Authors: Furlanetto Maria Marta , Ribeiro Vinicius Valença
Published: December 2016

RESUMO Este artigo apresenta uma análise dos indícios de autoria em três resenhas produzidas por alunos do segundo e do terceiro ano do Ensino Médio do Instituto Federal de Sergipe. Os pressupostos teóricos envolvem a perspectiva sociointeracionista do Círculo de Bakhtin e as orientações sugeridas por Possenti (2009a, 2009b, 2013). A teoria sociointeracionista norteia o planejamento para o trabalho com gêneros, autoria e estilo; as concepções de Possenti são mais específicas para o trabalho pedagógico com os indícios de autoria a partir da produção textual dos alunos, na qual se verifica o nível de controle dos recursos linguísticos. Na análise, avaliam-se as associações com elementos da cultura assim como as ocorrências de possíveis decisões enunciativas dos produtores, envolvendo tanto as escolhas vocabulares quanto a variação dos aspectos formais dos textos. Procura-se também relacionar as resenhas escolares a um lugar de enunciação. Esses aspectos mostram-se pertinentes para mapear os indícios de autoria nas resenhas analisadas.
O ENSINO DE LÍNGUA INGLESA E A IDENTIDADE DE CLASSE SOCIAL: ALGUNS APONTAMENTOS
Authors: Santos Gabriel Nascimento dos , Mastrella-de-Andrade Mariana Rosa
Published: December 2016

RESUMO O ensino da língua inglesa é um importante meio de construção de identidades sociais, dentre elas, a de classe (BLOCK, 2013). Entretanto, o número reduzido de investigações a esse respeito tem deixado de chamar a atenção para sua importância. Neste artigo, buscamos discutir por que a questão da identidade de classe social deve se tornar um aspecto relevante a ser considerado e investigado no ensino-aprendizagem de línguas, em especial aqui em relação à língua inglesa. Também buscamos, por meio da Análise de Discurso Crítica (FAIRCLOUGH, 2003, VAN DIJK, 2015), apresentar um recorte de uma pesquisa que investiga de que maneira o livro didático, um instrumento de autoridade na sala de aula (TÍLIO, 2010; CORACINI, 1999), constrói identidades de classe social e quais os significados dessas identidades. Os resultados reforçam a premissa de que o ensino de inglês é, em grande medida, espaço de construção de identidades de classe, contribuindo para a manutenção de exclusões e desigualdades.
ERRORES DE TRANSFERENCIA EN COMUNIDADES DE APRENDIZAJE EN LÍNEA POR APRENDIENTES DE ESPAÑOL COMO LENGUA EXTRANJERA (ELE)
Authors: Elejalde Gómez Jessica , Ferreira Cabrera Anita
Published: December 2016

RESUMEN Las comunidades de aprendizaje de lenguas en línea ofrecen espacios gratuitos para practicar la escritura en la lengua meta, donde los aprendientes publican experiencias y/o relatos de diversos tipos. Esta escritura se gesta en el marco de una producción libre caracterizada por la naturalidad con las que son escritas, sin una intervención directa de la instrucción formal en una clase presencial. Este hecho podría reflejar un estado real de la lengua meta y, como consecuencia, evidenciarse la influencia de la lengua materna producto de la condición espontánea que ofrece la comunidad de aprendizaje en línea. En este contexto, se presentan los resultados de un estudio descriptivo basado en el análisis de errores de un corpus de 400 textos escritos por 80 aprendientes de ELE (Español como Lengua Extranjera) de diferentes comunidades. El objetivo es determinar cuáles son los errores de transferencia más frecuentes que ocurren en este tipo de ambiente de aprendizaje. La lengua materna de los sujetos es el inglés y el alemán con un nivel de proficiencia B1 declarado. Los resultados revelan que los errores de transferencia más frecuentes son: 1) los errores producto de interferencias de estructuras gramaticales como la omisión o adición de categorías gramaticales, 2) errores relacionados con la interferencia de estructuras y funciones sintácticas y 3) errores morfológicos y gráficos. Los resultados obtenidos en este estudio aportan una nueva perspectiva sobre el fenómeno de la transferencia según el ambiente de aprendizaje mediatizado por la tecnología y la producción escrita en ELE.
EFL STUDENTS' METAPHORICAL CONCEPTUALIZATIONS OF LANGUAGE LEARNING
Authors: Farías Miguel , Véliz Leonardo
Published: December 2016

ABSTRACT Traditional approaches to metaphor have focused primarily on its ubiquity in language and thought. Recently, a growing interest in the pervasiveness of metaphor in modes other than purely linguistic ones has been explored. In this paper particular attention is paid to non-verbal forms of metaphorical depiction. We have examined a small corpus of EFL students' drawings and narratives in order to both tap into their mental representations of what 'language learning' means to them and get closer insights into these learners' belief system. We approach the analysis multimodally, by scrutinizing the various meaning-making potentials of images and text as they conceptualize the learners' perspectives of English language learning. To frame the study of these metaphorical representations, we take Block's (2003) 'acquisition' and 'participation' metaphors and Oxford et al.'s (1998) perspectives on education. Results indicate that most of the visual and narrative metaphorical depictions portray language learning as a dynamic, individual acquisition process and can, therefore, be comprehended primarily through the Learner-Centered Growth perspective.
Qualidade sanitária da água distribuída para abastecimento público em Rio Verde, Goiás, Brasil
Authors: Morais Wilker Alves , Saleh Bruno Botelho , Alves Wellmo dos Santos , Aquino Davi Santiago
Published: December 2016

Resumo Águas distribuídas para abastecimento público precisam obedecer ao padrão de potabilidade em vigor para que sejam sanitariamente seguras, visando não expor a população abastecida a riscos epidemiológicos inerentes às doenças de veiculação hídrica. Este trabalho teve como objetivo avaliar a qualidade da água distribuída aos habitantes de três bairros da cidade de Rio Verde, em Goiás. Foram realizadas quatro coletas semanais nos dias 7, 14, 21 e 28 do mês de dezembro de 2012, em três pontos selecionados. Os parâmetros analisados foram temperatura (T), sólidos totais dissolvidos (STD), condutividade elétrica (CE), turbidez (Turb), pH, cloro residual livre (CRL), coliformes totais (CT) e Escherichia coli (E. coli). As médias dos resultados foram comparadas com os limites estabelecidos pela Portaria do Ministério da Saúde nº 2.914/2011. Todas as amostras atenderam aos limites determinados pela referida Portaria com relação aos parâmetros STD, Turb, pH, CT e E. coli. O sistema de abastecimento de água analisado apresentou inconformidade quanto ao nível de CRL em dois bairros, o que pode comprometer a saúde da população atendida. Os procedimentos operacionais na etapa de desinfecção do tratamento da água devem ser retificados para que os níveis de CRL na rede de distribuição atendam aos limites legais.
Fatores associados aos sentimentos decorrentes da perda dentária total e às expectativas de reposição protética em adultos e idosos
Authors: Probst Livia Fernandes , Ambrosano Gláucia Maria Bovi , Cortellazzi Karine Laura , Guerra Luciane Miranda , Ribeiro-Dasilva Margarete , Tomar Scott , Ciarântola Marina , Konkowski Isadora Prata Soldi , Possobon Rosana de Fátima
Published: December 2016

Resumo Introdução A perda dentária é considerada um evento grave na vida dos pacientes e pode levá-los à reclusão social. A reabilitação por meio de próteses pode contribuir para a melhora da autoimagem de edêntulos totais. Objetivo Este estudo teve como objetivo conhecer os fatores associados aos sentimentos decorrentes da perda de dentes e às expectativas quanto à nova prótese. Métodos Estudo transversal analítico com 119 pacientes edêntulos totais (faixa etária entre 29 e 87 anos) em tratamento para confecção de prótese em uma clínica-escola. Resultados Os pacientes que relataram ter perdido seus dentes devido ao medo de submeter-se ao tratamento ou a dificuldades de acesso foram os que mais sofreram com a perda dentária (OR=2,57). Os pacientes mais jovens (OR=3,33) e do sexo feminino (OR=3,89) foram aqueles que demonstraram mais expectativas em relação à prótese que estava sendo confeccionada. Conclusão As mulheres e as pessoas mais jovens são aquelas que manifestaram mais raiva ou tristeza pela perda dentária e que possuíam expectativas estéticas e de socialização em relação à nova prótese.
MODELING THE NEW FRANCHISE CREATION DECISION: THE RELEVANCE OF BEHAVIORAL REASONS
Authors: AGUIAR HELDER DE SOUZA , PAULI SERGI , YU ABRAHAM SIN OIH , NASCIMENTO PAULO TROMBONI DE SOUZA
Published: December 2016

ABSTRACT Purpose: Franchising is one of the fastest-growing operating modes in Brazil. In 2014, the Brazilian Franchising Association reported 2,492 active brands in the country. Some theories with an economic point of view, such as the agency theory, plural forms theory, or scarcity principle, explain why companies choose franchising. However, did the decision makers and founders of these franchises decide on this strategy taking only economic reasons into consideration? The purpose of this study is to understand the a priori criteria (prior to the decision) that executives took into account when adopting this strategy and the key motivations for this decision. Originality/gap/relevance/implications: The literature emphasizes the economic reasons for the success of the franchise model, but it does not focus on the founders' motivations when they choose this strategy. This is the gap that this study seeks to address. Dissonance could arise between economic reasons and entry motivations that could result in consequences for the management of new franchises. Key methodological aspects: Ten companies of different industries and different life cycle stages involved with the franchise model were scrutinized using a semi-structured questionnaire based on the literature on decision theory and franchising. Summary of key results: Behavioral factors significantly influence decision makers when choosing the franchise model. Key considerations/conclusions: This study distinguishes the economic reasons from the executives' motivations when choosing the franchise model and highlights the importance of non-economic factors in this decision.
ENTREPRENEURIAL POTENTIAL AND SUCCESS IN BUSINESS: A STUDY ON ELEMENTS OF CONVERGENCE AND EXPLANATION
Authors: SOUZA GUSTAVO HENRIQUE SILVA DE , SANTOS PAULO DA CRUZ FREIRE DOS , LIMA NILTON CESAR , CRUZ NICHOLAS JOSEPH TAVARES DA , LEZANA ÁLVARO GUILLERMO ROJAS
Published: December 2016

ABSTRACT Purpose: The study aimed to verify whether there is a difference of entrepreneurial potential between successful entrepreneurs and entrepreneurs who have failed; and whether there are variables that may work as a means of prediction to the success or failure of an entrepreneur. Originality/gap/relevance/implications: It brings up an innovative approach to the entrepreneurship researches, which main content is in the empirical operationalization of success and failure on business for the testing of specific hypothesis and the identification of the antecedents and consequences of entrepreneurial potential. Key methodological aspects: The research was conducted on a descriptive and quantitative approach. We applied the scale of entrepreneurial potential in 246 entrepreneurs, which 100 correspond to the analysis criteria, operationally, as successful entrepreneurs (n = 50) and entrepreneurs who failed (n = 50). Data were analysed by statistics techniques of logistic regression and Student's t test. Summary of key results: Results show that the successful entrepreneur has higher scores in entrepreneur potential scale than the entrepreneur who failed, in which the main convergence between entrepreneurial potential and business success is the setting business goals. In the investigated sample, the gender showed being a strong predictor of business success, indicating that men have 2.8 times greater chance of success in business than women. Key considerations/conclusions: In our opinion, the results found shed light on crucial elements to the explanation of business success and corroborate recent results brought by research on entrepreneurship and gender.
WHAT TOMORROW BRINGS? EXAMINING A MODEL OF ANTECEDENTS OF CAREER EXPECTATIONS
Authors: VASCONCELLOS VINICIUS CARVALHO DE , NEIVA ELAINE RABELO
Published: December 2016

ABSTRACT Purpose: Analyze if the perceptions about policies and practices on human resources management (HRM), well-being at work and expectations of organizational future act as antecedents of career expectations in the organization. Originality/gap/relevance/implications: The question "What will my future be in this organization?" is a relevant part of working life. Thus, it is important to assess which variables influence future career expectations. Based on theoretical contributions and previous surveys about career, well-being and HRM, the model tested coordinates variables that are analyzed in isolate by literature. Key methodological aspects: In this quantitative survey, 305 professionals from a government agency completed an e-questionnaire with scales validated in Brazil. Data were analyzed through structural equations models. Summary of key results: The effects of well-being at work and expected future in the organization on the career expectations were positive and moderate, in the first case, and strong in the second case. The effect of perceptions of HR policies and practices on career expectations was completely mediated by well-being at work and expectations of organizational future. Key considerations/conclusions: Results support the relations theoretically conceived or found in previous qualitative surveys. In practical terms, data suggest that improving HR policies and practices can increase well-being at work and expectations of organizational future and, finally, foster positive career expectations in the organization. Considering that the research was limited to one organization, future investigations should analyze the model in other organizations.
MEANINGS OF VOLUNTEER WORK: A STUDY WITH MEMBERS OF A LUTHERAN INSTITUTION
Authors: BORCHARDT PIETRA , BIANCO MÔNICA DE FATIMA
Published: December 2016

ABSTRACT Purpose: To understand the meanings of volunteer work among members of a lutheran protestant church. Originality/gap/relevance/implications: This research adds to the field of knowledge of the meanings of work, especially because of the specific context studied. In addition, it extends the discussion on volunteering, by entering the management of religious institutions that are supported by the help of volunteers. Key methodological aspects: A qualitative approach to research was adopted and data were gathered in documents, interviews, and non-participant observation of the board meetings of a lutheran church synod in Southeast Brazil. The perspective used to analyze data was that the production of meanings is also a means for interpreting. Besides, using associating ideas mapping technique allowed the identification of categories based on the content and logical sequence of discourse. Summary of key results: The study found eight meanings of work: identification with the lutheran ethics; integrity and image of the institution; unit; conditions and willingness to participate; incentive from others; relation with the profession; pleasant relationship between a board of directors; and monitoring, support, and recognition. Key considerations/conclusions: The study revealed a better understanding for volunteering at a religious organization on how to think about ways to manage it. Also, it was realized that the experiences and interaction with others shape the individual and his or her relationship with the church, and that the meaning of work has a different relationship to each religion.
Spontaneous intracranial epidural hematoma during rivaroxaban treatment
Authors: Ruschel Leonardo Gilmone , Rego Felipe Marques Monteiro do , Milano Jerônimo Buzetti , Jung Gustavo Simiano , Silva Jr Luis Fernando , Ramina Ricardo
Published: December 2016

Summary According to our research, this is the first case described in the literature of spontaneous intracranial epidural hematoma secondary to the use of Xareltor. Spontaneous intracranial epidural hematomas are rarely described in the literature. They are associated with infectious diseases of the skull, coagulation disorders, vascular malformations of the dura mater and metastasis to the skull. Long-term post-marketing monitoring and independent reports will probably detect the full spectrum of hemorrhagic complications of the use of rivaroxaban.
Prevalence and management of anemia in pre-dialysis Malaysian patients: A hospital-based study
Authors: Salman Muhammad , Khan Amer Hayat , Adnan Azreen Syazril , Sulaiman Syed Azhar Syed , Hussain Khalid , Shehzadi Naureen , Islam Muhammad , Jummaat Fauziah
Published: December 2016

Summary Objective: Anemia, a common complication of chronic kidney diseases (CKD), is involved in significant cardiovascular morbidity. Therefore, the objective of our study was to investigate the prevalence and severity of anemia in pre-dialysis patients, as well as to determine the predictors of anti-anemic therapy. Method: A retrospective, observational study was conducted on adult pre-dialysis patients receiving treatment at the Hospital Universiti Sains Malaysia from January 2009 to December 2013. Results: A total of 615 eligible cases were included. The mean age of patients was 64.1±12.0 years. The prevalence of anemia was 75.8%, and the severity of anemia was mild in 47.7% of the patients, moderate in 32.2%, and severe in 20%. Based on morphological classification of anemia, 76.9% of our patients had normochromic-normocytic anemia whereas 21.8 and 1.3% had hypochromic-microcytic anemia and macrocytic anemia, respectively. Oral iron supplements were prescribed to 38.0% of the patients and none of the patients was given erythropoietin stabilizing agents (ESA) or intravenous iron preparations. In logistic regression, significant predictors of anti-anemic preparation use were decreased hemoglobin and hematocrit, and advanced stages of CKD. Conclusion: The results of the present study suggest that the prevalence of anemia in pre-dialysis patients is higher than currently accepted and it is found to be correlated with renal function; prevalence increases with declined renal function. An earlier identification as well as appropriate management of anemia will not only have a positive impact on quality of life but also reduce hospitalizations of CKD patients due to cardiovascular events.
Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors
Authors: Ramos Edneia A. S. , Silva Camila T. da , Manica Graciele C. M. , Pereira Isabela T. , Klassen Liliane M. B. , Ribeiro Enilze M. S. F. , Cavalli Iglenir J. , Braun-Prado Karin , Lima Rubens S. , Urban Cicero A. , Costa Fabrício F. , Noronha Lucia de , Klassen Giseli
Published: December 2016

Summary Introduction: Breast cancer is the most cause of death, and approximately 90% of these deaths are due to metastases. Matrix metalloproteinase-2 (MMP-2) gelatinase activity is able to degrade a major constituent of the tumor microenvironment, type IV collagen. Two well-established proteins used as markers in clinical practice for breast cancer are the receptors for estrogen (ER) and progesterone (PR). Although the presence of these receptors has been associated with a better prognosis, loss of these proteins can occur during tumor progression, with subsequent resistance to hormone therapy. Objective: To study the correlation among MMP-2, ER, and PR, as well as the establishment of the metastatic process in primary breast tumors. Method: Breast cancer samples (n=44) were analyzed by immunohistochemistry for MMP-2, ER, and PR. Results: We observed that 90% of patients who had metastases and died showed positive staining for MMP-2 (p=0.0082 for both). Using Kaplan-Meier analysis, we found that negative ER patients who were also positive for MMP-2 had even worse disease-free survival (DFS) and overall survival (OS) (p= 0.012 and p=0.005, respectively). Similar results were found in PR-negative patients for DFS (a trend p=0.077) and OS (p=0.038). Conclusion: Regardless of our small sample size (n=44), the data obtained strongly suggest that MMP-2 in combination with already well-established markers could help to predict the emergence of metastases and death in patients with breast cancer.
Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
Authors: Moraes Fabio Ynoe , Bonifacio Lorine Arias , Neves-Junior Wellington Pimenta , Hanna Samir Abdallah , Abreu Carlos Eduardo Cintra Vita , Arruda Fernando Freire , Silva João Luis Fernandes , Carvalho Heloisa Andrade
Published: December 2016

Summary Objective: To provide a quantitative profile of the indications and use of stereotactic body radiotherapy (SBRT) in a developing country oncology-based institution. In addition, to describe the patients' and treatment characteristics, and to provide a temporal analysis. Method: SBRT patients treated from 2007 to 2015 were retrospectively evaluated by two independently investigators. Data were stratified and compared in two periods: first experience (FE) (May 2007 to April 2011), and following experience (FollowE) (May 2011 to April 2015). The following parameters were compared between the groups: total number of treated patients and lesions, treatment site, additional image fusion used, formal protocol adoption, and SBRT planning technique. Results: One hundred and seventy-six (176) patients with 191 lesions were treated: 34 (18%) lesions in the FE and 157 (82%) lesions in FollowE. The majority of lesions were metastases (60.3%), and lung (60.2%) was the most common treatment site, followed by spine (31%), and others (8.8%). An average of 1.4 (±0.6) additional imaging exams for delineation was performed. Conformal 3D radiotherapy planning technique was used in 64.4%, and intensity modulated radiotherapy (IMRT) or volumetric-modulated arc therapy (VMAT) in the remaining 35.6% (p=0.0001). Higher rates of curative treatments were observed in FE, as well as more lung lesions, patients ≥ 70 years, 3D conformal, number of additional images and ECOG 0, and all presented p<0.05. The global rate of protocol statement was 79%, lung treatment being the most stated. Conclusion: SBRT application is rapidly increasing in our setting. Treatment sites and planning techniques are becoming more diversified and complex.
Educational strategies for the prevention of diabetes, hypertension, and obesity
Authors: Machado Alexandre Paulo ,   Universidade Federal de Mato Grosso, Brazil, Lima Bruno Muniz , Laureano Monique Guilharducci , Silva Pedro Henrique Bauth , Tardin Giovanna Pereira , Reis Paulo Silva , Santos Joyce Sammara , Jácomo Neto Domingos , D'Artibale Eliziana Ferreira ,   UFMT, Brazil
Published: December 2016

Summary Objective: The main goal of this work was to produce a review of educational strategies to prevent diabetes, hypertension, and obesity. Method: PubMed database was consulted using combined descriptors such as [Prevention], [Educational Activities], [Diabetes], [Hypertension], and [Obesity]. Data from randomized trials published between 2002 and 2014 were included in spreadsheets for analysis in duplicate by the reviewers. Results: A total of 8,908 articles were found, of which 1,539 were selected about diabetes mellitus (DM, n=369), arterial systemic hypertension (ASH, n=200), and obesity (OBES, n=970). The number of free full text articles available was 1,075 (DM = 276, ASH = 118 and OBES = 681). In most of these studies, demographic characteristics such as gender and age were randomized, and the population mainly composed by students, ethnic groups, family members, pregnant, health or education professionals, patients with chronic diseases (DM, ASH, OBES) or other comorbidities. Group dynamics, physical activity practices, nutritional education, questionnaires, interviews, employment of new technologies, people training and workshops were the main intervention strategies used. Conclusion: The most efficient interventions occurred at community level, whenever the intervention was permanent or maintained for long periods, and relied on the continuous education of community health workers that had a constant interference inside the population covered. Many studies focused their actions in children and adolescents, especially on students, because they were more influenced by educational activities of prevention, and the knowledge acquired by them would spread more easily to their family and to society.
Simultaneous optimization of coffee quality variables during storage
Authors: Abreu Giselle F. de , Rosa Sttela D. V. F. da , Cirillo Marcelo A. , Malta Marcelo R. , Clemente Aline C. S. , Borém Flávio M.
Published: December 2016

ABSTRACT The objective of the study was to use methodology of simultaneous optimization of multiple responses applied to an experimental design to determine the best combination of storage period and conditions for preservation of coffee beans. Coffea arabica L. fruits were harvested in the ripe stage of maturation, processed using wet and dry methods, and dried to 11% (wet basis) moisture content. Part of the beans was hulled, while the other part was hulled only after the beans were stored under two different environmental conditions: cooled air at 10 ºC with 50% relative humidity; and at 25 ºC without controlling the relative humidity. Samples were taken at 3, 6, and 12 months intervals in order to evaluate quality. The data were submitted to the simultaneous optimization of responses for each processing and hulling condition separately, in a completely randomized design and 2 x 3 factorial scheme (two storage conditions and three storage periods). In conclusion, the use of the simultaneous optimization of responses is viable to be applied for determining the ideal storage conditions in a refrigerated condition.
Relationship between biospeckle laser technique and firmness of Acrocomia aculeata fruits
Authors: Costa Anderson G. , Pinto Francisco A. C. , Braga Roberto A. , Motoike Sergio Y. , Gracia Luis M. N.
Published: December 2016

ABSTRACT Knowing the maturation of the Acrocomia aculeata (macaw palm) fruit is decisive for harvest to be performed when the fruit has a higher content and quality of oil. There are different approaches to monitor maturation and they can be classified as destructive and non-destructive. Variables obtained by optical instruments have been used to determine maturation stage. The present study evaluated the relationship between the biological activity measured by the optical technique of biospeckle laser and firmness, measured in the Acrocomia aculeata fruit pulp between the 41st and 61st week after flowering. The biological activity was quantified by biospeckle images, while the fruit pulp firmness was determined by digital penetrometer. Correlations between variables were evaluated during maturation and in the senescence of fruits. According to the results, significant correlation between biological activity and firmness was found for both evaluated conditions, demonstrating that biospeckle laser can be an effective non-invasive indicator of Acrocomia aculeate fruit maturation assisting in the determination of the moment of harvest.
Kiju Sakai: o antropólogo japonês que dedicou sua vida a estudar o Brasil na primeira metade do século XX
Authors: Hattori Marcia Lika , Strauss André
Published: December 2016

Resumo Kiju Sakai foi um antropólogo e arqueólogo japonês que veio ao Brasil em 1934. Ao longo de sua vida, ele escavou diversos sítios e formou uma importante coleção arqueológica. Até recentemente, essa coleção não estava institucionalizada e a biografia de Sakai era desconhecida. O estudo apresenta a história de constituição desta coleção, a partir da vida do antropólogo, e trazer dados sobre a curadoria do material, seus desdobramentos e contribuições para a história da Arqueologia brasileira no início do século XX e o papel dos ‘amadores’ e de instituições como a Sociedade Archaeológica Brasileira de Amadores (SABA) e o Instituto Kurihara nas pesquisas desenvolvidas no estado de São Paulo. A “Coleção Arqueológica Kiju Sakai” se encontra hoje no Museu Histórico e Arqueológico de Lins, no estado de São Paulo, e conta com os mais distintos tipos de material arqueológico, dentre os quais se destacam: cerâmicas Tupi e Jê; remanescentes humanos, provenientes de sambaquis e de montículos funerários Kaingang; artefatos líticos, lascados e polidos, de sambaquis; pontas feitas de ferro; e medalhas do Serviço Nacional de Proteção ao Índio. Além do material arqueológico, também se encontra no acervo a documentação primária que Sakai produziu, incluindo mapas de dispersão linguística na América do Sul escrito em japonês, diários de campo e aquarelas representando os motivos presentes em cerâmica Tupi.