bluuebunny/crossref_metadata_2025 huggingface dataset:
Environmental assessment of the copper content in the soil cover in the South of the Tyumen Region
Authors: Sindireva Anna V. , Kotchenko Sergey G. , Elizarov Oleg I.
Published: April 2022

The article presents data on the content of copper in the plow horizon of the main types of soils of the Tyumen region used in agricultural production, and determines the relationship of its distribution with the main physical and chemical indicators of soils (humus, pH, macroelements). To analyze the geochemical features of the microelement distribution in the soil cover, field, laboratory, and statistical research methods were used. When summarizing and analyzing the material, we used our own research and materials from the reports of the FGBU GSAS Tyumenskaya on the survey of arable soils in the Tyumen region. In all studied types of soils in the south of the Tyumen region, excess of the permissible concentrations of copper is not observed. The content of mobile forms of copper, depending on the type and subtype of soils, varies in the range from 0.15 to 0.25 mg/kg, the total content ranges from 10 to 18 mg/kg. The ratio of the mobile form to the gross content is from 1.05 to 2.29%. A reliable relationship between mobile copper and its total content has not been established. A close correlation has been established between the total content of copper and mobile forms of potassium, humus and the pH level. For mobile forms of copper, there is an average correlation with the content of humus in soils. The relationship between the mobile forms of copper and phosphorus has not been established. The data obtained can be used in environmental monitoring as initial, background reporting points in assessing the degree of pollution of agrocenoses, as well as in predicting the effect of copper in the soil-plant system in the south of the Tyumen region.
Ecological and taxonomic structure of winter algocoenosis in the rivers of the Sevastopol region
Authors: Didenko Ivan N. , Didenko Nadezhda A. , Skorobogatova Olga N. , Storchak Tatiana V.
Published: April 2022

The paper considers the ecological and taxonomic structure of the winter algocoenosis of the Chernaya, Kacha, and Belbek rivers within the territory of the city of Sevastopol. The results of studies were obtained on 30 chemical and physical parameters of surface water samples during the period of algological sampling. The collection of field material (phytoplankton, algae in fouling, on various substrates immersed in water) and its processing was carried out according to the methods generally accepted in algological practice. The diagnostic features, as well as the similarities and differences in the species diversity of algae, have been determined. The studies carried out show that the studied algocoenosis are characterized in winter period by a rich species composition, with a significant predominance of diatoms. The algae found in the studied rivers are indicators of water purity, and their occurrence activity and abundance can indicate that the content of organic matter in the waters of the Belbek and Kacha rivers is lower than in the Chernaya river. This is confirmed by the presence of algae xenosaprobionts in the waters of the Belbek and Kacha rivers, which are indicators of clean, not polluted, with organic substances water.
Technical Efficiency, Productivity, and Determinants of Technical Inefficiency of Local Hospitals in Oman: Using Data Envelopment Analysis
Authors: Al Subhi Moosa
Published: April 2022

Purpose of the study: Evidence suggested that inefficiency is a significant problem for many health systems around the world and, in particular, in developing countries. Oman's health system increasingly faces critical resource constraints to deliver the same or better health services. Better utilization of hospital resources will enable more services to be provided and allow the redistribution of potential resources to ensure equity, accessibility, and the delivery of sustainable quality care. Therefore, this study aims to assess the technical efficiency, productivity, and determinates of technical inefficiency of local hospitals in Oman.

Methodology: Input-oriented Data Envelopment Analysis (DEA) approach was used to assess the technical efficiency of 29 local hospitals in Oman under constant return to Scale (CRS), variable returns to scale (VRS) and scale efficiency (SE) using 2018 data. Tobit model was used to assess the determinants of hospital inefficiency. The DEA based Malmquist Productivity Index (MPI) was applied to the panel data to measure the Total Factor Productivity Change (TFPCH) between 2015 and 2018. The STATA IC 16 software was used to conduct this evaluation.

Main Findings: 75.8% of local hospitals were technically efficient under VRS and SE assumptions, and 79.3% achieved technical efficiency under CRS assumption. The average technical efficiency score under CRS, VRS and SE were 96%, 97% and 99%, respectively. Tobit's model suggested that the number of physicians and pharmacists negatively correlated with the VRS score at p level < 0.05 and < 0.01, respectively. Furthermore, the Tobit model suggested that the number of outpatient’s visits positively correlated with the VRS efficiency score at p level < 0.01. Local hospitals showed a productivity growth by 18.1% during 2015-2018, mainly attributed to the increase in technological change by 42.6%.

Research Implications: The results suggested that one-quarter of local hospitals in Oman were technically inefficient. This study identifies opportunities for improving local hospital performance through efficient utilization of health resources and proper redistribution of human resources.

The novelty of the study: This is the first study to assess the technical efficiency, productivity, and determinants of technical inefficiency of local hospitals in Oman. It is hoped that the findings of this study can inform decision-makers to tailor their policies towards better and more efficient utilization of the existing resources.
Sexuality in a Diverse Society: Perspectives on the Quality Matters/Gold Review Process for Online Course Transition
Authors: Robinson David , McFadden Carrie
Published: April 2022

Background: As student demand for online learning grew, Towson University adopted the quality assurance standards based from The Quality Matters Program and developed the Gold Review Process. The process, supported by research and best practices, was used as a professional development rubric for instructors initiating the conversion from classroom-based instruction to an online learning environment. Purpose: To evaluate the perspectives of the Course Instructor and of the QM peer gold reviewer during their experience of taking a course through the QM Gold Review redesign process. Methods: Peer review data, student course evaluation data and instructor reflections are presented and analyzed as measures to reflect on the transformation and implementation of a selected course to a fully online format via the Gold Review process. Results and Recommendations for the Field: As higher education institutions reallocate resources, time, and expertise to online course design and implementation, quality assurance processes like Gold Review and Quality Matters, can facilitate the successful design of courses to reflect sound pedagogy, course alignment and accessibility.
Examining K-12 Students’ Preferences and Attitudes on Mobile Learning
Authors: Tuncer Can Sevda Kucuk , Tuncer Can Irfan Simsek
Published: April 2022

The aim of this study is to examine K12 students’ preferences and attitudes on mobile learning. In this study, causal-comparative method was used. The sample of the study were 236 students (127 females, 109 males) at K12 level. The students are enrolled in primary (n=104), secondary (n=77), and high school (n=55) levels. The data in the study were collected through a questionnaire. According to the results, watching videos, playing music, playing games, taking a picture, accessing the Internet are the most common uses of mobile devices for the students. The students’ attitudes towards mobile learning is highly positive. The male students’ perceived ease of use towards mobile learning is higher than females. The secondary and high school students’ perceived ease of use is higher than primary school students. Moreover, the high school students’ desire for learning is higher than the others. Implications were discussed in terms of practices for mobile learning in K12, and directions for further research.
Assessing Pre-service Teachers' Attitudes towards Research Courses in Colleges of Education
Authors: Jacob Issaka  , Hammond Daniel Kwasi , Nomah Emmanuel , Fiawoo Duncan Dodzi
Published: April 2022

Research plays a critical role in the building of knowledge and solving of societal problems. This study seeks to assess pre-service teachers for research courses in the Colleges of Education in the Oti region of Ghana. The study aims to assess pre-service teachers' attitudes towards research courses in the Colleges of Education in the Oti Region of Ghana. The study adopted a quantitative design. The survey research method was, however, used because it helps to collect data on attitudes. Simple random sampling was used to select 200 respondents. The data collection instrument used was a questionnaire. The data were analysed using descriptive and correlational statistical analysis. It was found that pre-service teachers have negative attitudes toward studying research methods and writing research project work. They see both research method and writing of research project work as complex and difficult, hence, they have high anxiety about research and dislike the research courses. It was concluded that the general attitudes toward studying research methods are directly linked to the perceived challenges of research. It is recommended that the challenges pre-service teachers face in learning research courses should be addressed to improve their attitudes towards research.
Single-cell differentiation trajectories define early stages of a human cutaneous T-cell lymphoma
Authors: Cerapio Juan‐Pablo , Perrier Marion , Pont Fréderic , Laurent Camille , Bertani Stéphane , Fournie Jean‐Jacques
Published: April 2022

Aim: The aim of this article is to characterize in detail the γδ T lymphocytes from an adult patient with primary cutaneous T-cell lymphoma of γδ subtype (γδ CTCL).
Methods: Here this article reports trajectory mapping on high-resolution differentiation trajectories of γδ T lymphocytes digitally extracted from a scRNAseq dataset.
Results: In the patch-to-plaque progression of CTCL, the TCRVγnon9 subset of γδ T cells differentiated from naive T cells (Tn) and central memory T cells (Tcm) to abundant effector memory T cells (Tem) while other cutaneous γδ T and CD8 T cells remained unchanged.
Conclusions: This transcriptomic switch underlies the emergence of a CTCL-like progression of the TCRVγnon9 γδ T subtype and suggests new routes for treating these diseases.
South american medicinal plants in jesuit documents: The “phytological observations...” by Gaspar Juárez and Filippo Gilii (1789-1792)
Authors:   Universidad Nacional de La Plata, Stampella Pablo C.
Published: April 2022

Interest is currently growing in Jesuit bibliography as a source of information on medicinal plants. One of the first steps is to taxonomically identify the plants involved. The objective of this work is to identify de South American medicinal plants from the “Phytological observations...” of Juárez and Gilii, discuss the identifications presented by the authors and compare with those of other Jesuit studies. The framework of historical ethnobotany was used forthe analysis of the aforementioned work. The plants were identified using various scientific publications. 17 ethnotaxa were surveyed, corresponding to 20 botanical species and two genera that comprise several species (Bromelia and Psidium), included in 13 botanical families. The identifications are consistent in most cases. In others, they correspond to a group of species (plant complex). Some of the local names do not correspond to the species described and identified.
Phytochemical and biological study of phenolic fraction from Geoffroea decorticans bark
Authors:   Centro Nacional de Investigaciones Cientifica y Tecnicas, Pastoriza Ana C , Sgariglia Melina A ,   Universidad Nacional de Tucuman, Soberon Jose R ,   Universidad Nacional de Tucuman, Sampietro Diego A ,   Universidad Nacional de Tucuman
Published: April 2022

The stem bark of Geoffroea decorticans (Gill.ex Hook. et Arn.) Burk. (Fabaceae) was used medicinally to cure several skin affections; however, previous phytochemical and biological antecedents that supported its vulnerary property were not found yet. A purified methanolic fraction from G. decorticans bark (PFGB), was derivatized by silylation for GC/MS analysis, and complementary analyses by two-dimensional TLC and UV-Vis spectroscopy against detected standards compounds. Nine phenolic compounds were characterized as gallic acid, quercetin, kaempferol, apigenin, protocatechuic acid, taxifolin, 4-Hydroxybenzoic acid; among these two methoxy-flavonoids. PFGB showed significant antibacterial activity (MICs= 125 μg/mL) against Staphylococcus aureus (25923) and Enterococcus faecalis (29212) ATCC strains. Cytotoxic effects on human lymphocytes activated or not by LPS were not observed up to 100 μg/mL, by MTT colorimetric assay. The resultsobtained through the ethnopharmacological approach of this work contribute to the scientific validation of the vulnerary medicinal use of G. decorticans.
Auto-hydrolysis of Tiquilia paronychioides (Phil.)A.T. Richardson and its relation to quercetin concentration
Authors:   Universidad Nacional de Trujillo, Llaure-Mora Alejandrina M , Ganoza-Yupanqui Mayar L ,   Universidad Nacional de Trujillo
Published: April 2022

The application of auto-hydrolysis of Tiquilia paronychioides (Phil.) A.T. Richardson aimed to determine the increase in quercetin concentration. Auto-hydrolysis was developed with aerial parts of T. paronychioides in aqueousmedium at 25°C with 20 rpm by 0, 2, 5, 8, 24, 48, 96 and 168 h, with 3 repetitions per test. Quercetin standards at concentrations of 5 to 80 ppm and auto-hydrolyzed extracts were evaluated by HPLC. The auto-hydrolyzed extracts showed Quercetin peaks from 8 h. Quercetin concentrations at 48, 96 and 168 h were 0.036 ± 0.0048, 0.033 ± 0.0105 and 0.026 ± 0.0068 mg quercetin/g, respectively, being statistically equal. In conclusion, the auto-hydrolysis of T. paronychioides generates the highest concentration of quercetin at 48 h.
Control of Apple Fruit Rot Caused by Alternaria porri and Alternaria mali by Using Hot Water Treatment and Some Inorganic Salts
Authors: Imhammed Aly Abdulla , Alhdad Gazala M.
Published: April 2022

Apple rot is one of the most important apple diseases worldwide. The disease causes significant losses in both the quantity and quality of apple fruits. In this study, the antifungal activity of hot water treatment and salts were investigated against apple fruit rots caused by Alternaria porri and Alternaria mali. Linear growth of tested fungi was inhibited at 5ºC, however, growth was increased by increasing storage temperature degree from 15ºC to 25ºC and decreased at 35ºC. On the other hand, hot water treatment at 55ºC significantly reduced the decay index and severity of infection. When salts such as potassium bicarbonate (KCO3), calcium chloride (CaCl2), sodium bicarbonate (NaHCO3) and ammonium bicarbonate (NH4CO3) was applied, a significant reduction in linear growth and fruit rot incidence was noticed using potassium bicarbonate. Calcium chloride, ammonium bicarbonate and sodium bicarbonate greatly inhibited growth of A. porri and A. mali. The most effective inhibitor of fruit decay was potassium bicarbonate and calcium chloride.
Optimalisasi Distribusi Tabung Gas Dengan Metode Clarke & Wright Saving Heuristik dan Generalized Assigment
Authors: Hartien Turid Hijri , Susetyo Joko , Asih Endang Widuri
Published: April 2022

PT. Boemi Surya Perkasa merupakan perusahaan yang bergerak dibidang distributor tabung gas LPG yang melakukan pendistribusian produknya kepada para pelanggan yang tersebar diwilayah Bantul. Berdasarkan hasil wawancara yang telah dilakukan, ternyata penentuan rute yang digunakan perusahaan hanya mempercayakan kepada sopir. Sehingga rute yang digunakan tidak tetap dan berubah-ubah. Hal tersebut dapat membuat jarak pendistribusian menjadi lebih panjang, sehingga biaya yang dikeluarkan untuk distribusi menjadi mahal. Penelitian ini dilakukan untuk menganalisis perbandingan hasil metode penyelesaian dalam Supply Chain Management (SCM) yaitu Clarke & Wright Saving Heuristik dan Generalized Assignment. Tujuan utama dari metode ini adalah perencanaan rute dan penugasan kendaraan dengan biaya distribusi yang optimal. Hasil dari penelitian yang dilakukan pada 38 retailer diketahui bahwa biaya yang dikeluarkan metode Clarke & Wright Saving Heuristik sebesar Rp. 1.353.346 per hari dapat memberikan penghematan sebesar Rp. 120.777 per hari (8 %) dibandingkan dengan penggunaan metode Generalized Assignment Rp. Rp. 1.314.365 per hari dengan penghematan sebesar Rp. 159.758 per hari (11%) dari biaya sebelumnya sebesar Rp. 1.474.123 per hari. Rute usulan yang optimal dihasilkan oleh metode Generalized Assignment (12 rute dengan total jarak tempuh sebesar 403,34 km) dibandingkan rute usulan yang dihasilkan dengan clarke & wright saving heuristik (12 rute dengan total jarak tempuh sebesar 489,93 km) dari 16 rute sebelumnya dengan total jarak tempuh 539,621 km. Rute yang dimiliki oleh Generalized Assignment lebih sederhana, fleksibel dan mempunyai kecepatan tinggi daripada Clarke & Wright Saving Heuristic.
Chinese Herbal Medicine Combined with Acupuncture-related therapy as Complementary Therapies for Diabetic Nephropathy: A Protocol for Systematic Review and Network Meta-Analysis
Authors:   Hubei University of Chinese Medicine, Wu Junsong , Liu Xuefeng , Liu Hejing , Wang Yang , Xiong Zhili , Shen Minyi , Zhong Kun
Published: April 2022

Review question / Objective: Evaluating the efficacy of various Chinese herbal medicines combined with acupuncture-related therapies in the treatment of diabetic nephropathy. Information sources: We will search the following databases for relevant randomised controlled trials: PubMed, EMBASE, Cochrane Library, Scopus, OVID,Web of Science, Cochrane Central Register of Controlled Trials, China Biology Medicine (CBM), the China National Knowledge Infrastructure (CNKI), Wanfang data, and the Chinese Scientifific Journal Database (VIP). Search until April 10, 2022, with a combination of MeSH terms and free words.
Uso Adecuado de los Dispositivos Digitales en el Proceso de Enseñanza-Aprendizaje Tiempos COVID-19
Authors: Betancurt-Loaiza María Consuelo , Cadena-Martínez Rodrigo
Published: April 2022

A pesar de tener una planeación definida se da un giro radical consecuencia del COVID-19, situación para la que nadie estaba preparado, y menos aún, el sector educativo. Por lo anterior, el presente artículo tiene como objetivo indagar sobre las estrategias y alternativas a utilizar para que los estudiantes de básica secundaria y media técnica de una institución educativa adquiera hábitos, estilos y modelos de autoaprendizaje en el uso adecuado de herramientas tecnológicas, contribuyendo al mejoramiento académico. La investigación se realizará bajo el método analítico, paradigma positivista, enfoque cuantitativo, diseño descriptivo, tipo no experimental; con una población aproximada de 212 estudiantes, muestra 84 y soportada en tres aspectos: (a) Sondeo inicial sobre equipos tecnológicos con los que se cuenta, manera de emplearlos; (b) Tiempo dedicado al uso; (c) Aplicación como material apoyo. La técnica de recolección de datos se realizará mediante formularios en Google Forms, acerca del uso adecuado de dispositivos digitales aplicados en el proceso enseñanza aprendizaje. El análisis se hará con porcentajes, utilizando la técnica de frecuencias respuestas escala tipo Likert. Finalmente, se determinará la necesidad de capacitación a la población en el uso adecuado de las Tecnologías de la Información y de la Comunicación (TIC); a la vez, rediseñar los planes de área, cambiando modelos tradicionales, que den importancia a las ayudas tecnológicas en las actividades escolares, independientemente si hay pandemia o no.
Raman fl uorescence technologies for early detection of infl ammatory and oncological disorders as a part of public health strategy and a tool for improving the quality of medical care: a review
Authors: Timurzieva A. B.
Published: April 2022

The increasing morbidity and mortality rate in inflammatory and oncological diseases requires determining the public health strategies for early  detection of such disorders and improving the quality of medical care. For this goal, high-tech modalities with high sensitivity, specificity and  accuracy are to be worked out. Rаman fluorescent medical technologies (RFMT) can be successfully applied in the diagnostics of inflammatory  and tumor diseases if to develop a specific algorithm for express analysis of histological, physiological, microbiological and other components  of biological tissues. The given article presents a brief overview on the application of Raman fluorescence spectrometry in the diagnostics  of diseases. This medical technology, which utilizes the phenomenon of tissue autoflorescence and Raman light scattering, is a promising  tool for early diagnostics of different inflammatory and oncological pathologies. The described nоn-invasive method allows to make an express  assessment of metabolic, morphometric and functional tissue parameters in intact and in pathological tissue. The present discussion is aimed  to find out points for the application of Rаman fluorescence spectrometry and its various modifications; to assess its potentials for screening;  to develop a specific algorithm for the diagnostics of inflammatory and tumor pathologies. RFMT is a promising modality for future applications  so as to improve the quality of medical care by early detection of inflammatory and tumor diseases and early prescription of rational therapy.
Methicillin-resistant Staphylococcus aureus infections in postpartum period
Authors:   “Filantropia” Clinical Hospital, Bucharest, Romania, Cigaran Ruxandra Gabriela , Gica Nicolae ,   “Filantropia” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Botezatu Radu ,   “Filantropia” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Ciobanu Anca Marina ,   “Filantropia” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Cimpoca-Raptis Brindusa Ana ,   “Filantropia” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Demetrian Mihaela ,   “Filantropia” Clinical Hospital, Bucharest, Romania, Gica Corina ,   “Filantropia” Clinical Hospital, Bucharest, Romania, Peltecu Gheorghe ,   “Filantropia” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Panaitescu Anca Maria ,   “Filantropia” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: April 2022

The overall risk of methicillin-resistant Staphylococcus aureus (MRSA) in obstetric populations is unknown. MRSA infection incidence has increased in pregnant women and neonates even if prevention techniques of MRSA have improved. MRSA infections affect both mothers and their infants. MRSA is the most common pathogen responsible for postpartum mastitis. There are also other postpartum infections with MRSA such as cellulitis, pelvic thrombophlebitis, pneumonia, septicemia, cesarean wound infections, episiotomy infections and urinary tract infections. The objectives of this review were to identify the most frequent risk factors for postpartum MRSA infection and to determine the frequency of antibiotic-resistant Staphylococcus aureus infections after delivery. A literature review was conducted using PubMed and we used the following key words “MRSA infection in postpartum”, “risk factors for postpartum MRSA infection”. We are included in our review 27 articles from the last 20 years which presented rare cases of MRSA infection in postpartum and those which identified the risk factors of this infection after delivery. Infections with MRSA appear to be more frequent among pregnant women colonized with MRSA. Early identification of MRSA, early diagnosis and appropriate treatment of infection is mandatory for a good prognosis. By now, vigilance and effective MRSA prevention strategies are considered essential to limit the spread and infection.
Fertility and pregnancy outcomes in patients with immune-mediated rheumatic diseases
Authors:   “Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania, Simionescu Anca ,   Filantropia Clinical Hospital, Bucharest, Romania, Daia-Iliescu Sinziana ,   “Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania,   “Sf. Maria“ Clinical Hospital, Bucharest, Romania, Cobilinschi Claudia ,   “Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania,   “Sf. Maria“ Clinical Hospital, Bucharest, Romania, Ionescu Ruxandra ,   “Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania,   Filantropia Clinical Hospital, Bucharest, Romania, Opris-Belinski Daniela ,   “Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania,   “Sf. Maria“ Clinical Hospital, Bucharest, Romania
Published: April 2022

Impaired fertility is an important public health concern, especially in patients with immune-mediated rheumatic conditions. Frequency of infertility /subfertility vary among rheumatic diseases – higher in systemic lupus erythematosus or rheumatoid arthritis, than in other autoimmune diseases. Risk factors like age, nulliparity, disease activity or medication such as NSAIDs, corticosteroids, cyclophosphamide are mostly encountered. Treating a pregnant woman is a challenge: the well-being of mother and child has to be considered, as tight disease control before, during pregnancy and postpartum is mandatory to minimize adverse outcome risk. Safety of biological therapies during preconception, pregnancy, and postpartum is crucial, anti-TNFs being safe in early pregnancy, second, but not third trimester. Etanercept and certolizumab may be considered for use throughout pregnancy due to low rate of transplacental passage. Concerning the child, live-attenuated vaccines are to be avoided for the first 6 months of life due to persistence of biologics.
The Relationship Between Malnutrition, Depressive Symptoms, and Cognitive Impairment in Geriatric Patients
Authors: CANSEL Neslihan , DATLI YAKARYILMAZ Funda
Published: April 2022

Aim: Malnutrition is an important health problem that is frequently seen in elderly individuals and has cognitive and psychological effects. In this study, it was aimed to evaluate the frequencies of malnutrition, cognitive impairment and depression in the elderly population and the relationship between these three variables.Material and Methods: In this retrospective study, data of 433 patients aged 65 and over who applied to a university hospital geriatrics outpatient clinic in Turkey were included. Nutritional status was evaluated with the Mini Nutritional Assessment Short Form (MNA-SF), depressive symptoms with the Geriatric Depression Scale-Short Form (GDS-15) and cognitive functions with the Mini Mental State Examination results (MMSE).Results: According to the MNA-SF results, 13.6% of the elderly were malnourished, 30% were at risk of malnutrition. Of all patients, 45.0% had a GDS-15 score of ≥5, 12.5% had severe dementia, and 24.7% had mild dementia. The frequency of depressive symptoms was 62.7% in malnourished patients, and 42.3% in those with malnutrition risk. Malnutrition and malnutrition risk were observed in 70.4% of patients diagnosed with severe dementia. There was a correlation between the severity of malnutrition and depressive symptoms and cognitive dysfunction.Conclusion: Malnutrition was common in the older population sample and was associated with cognitive impairment and depressive symptoms. These findings emphasize that counseling and psychiatry services should be provided to risky groups and they should be evaluated regularly for early diagnosis.
On the Stellar Metallicity Distribution Resulting from a Disrupted Milky Way Globular Cluster System
Authors: Smith Graeme H.
Published: April 2022

Consideration is given to the stellar metallicity distribution that would result from a hypothetical dissociation of all Milky Way globular clusters into field stars, and several characteristics are compared to an exponential distribution.
Effects of Tele-Exercise on Body Weight, Body Mass Index, and Fat Mass of Obese Employees
Authors: Kuswari Mury , Rimbawan Rimbawan , Hardinsyah Hardinsyah , Dewi Mira , Gifari Nazhif
Published: April 2022

Purpose: Obesity is a growing health problem in Indonesia caused by physical inactivity. Meanwhile, employees are a group that is susceptible to obesity as they often have limited time while working sedentarily in front of a desk or computer, especially during the COVID-19 pandemic. This causes risks of many cardiovascular diseases, obesity and can indirectly cause death. Tele-exercise, a live online video exercise, may be the solution to this problem. Therefore, the purpose of this study is to analyse the effects of tele-exercise on body weight, BMI, and fat mass percentage as indicators of obesity. Methods: The research was conducted from July 2020 to January 2021 according to the policy regarding the pandemic. Also, it used a pre-post quasy experimental design. A total of 39 subjects were given tele-exercise involving 2 strength training and 1 cardio training per week for 3 months. Findings: Subsequently, the results showed that exercise had a significant effect (p<0.05) on BMI and body weight, while fat mass percentage only decreased significantly (p<0.05) from the second to third assessment. Originality: To our knowledge, this is the first study analysing the effects of tele-exercise on obese employee’s body weight, body mass index and fat mass. Conclusion: This proves that tele-Exercise is an effective therapy for obesity that does not require a large space, and has beneficial online aspects, especially during the pandemic. The timing of measurement and hydration status should be considered to assess the body composition.
The Influence of Family Planning Pocketbook on Cadres’ Knowledge and Skills in Changing the Couples Perceptions in Special Region of Yogyakarta
Authors: Paramita Dyah Pradnya , Mulyaningsih Sundari , Alfiana Ratih Devi , Fitri Gita Cahya , Nurunniyah Siti
Published: April 2022

BACKGROUND: The number of traditional contraceptive methods used in the National Health Insurance (JKN) era is increasing compared to the previous year. One of the contributing factors is the public’s negative perception due to the lack of information about modern family planning. Consequently, family planning cadres are needed to provide accurate information to change people’s negative perceptions of modern family planning. A guideline written in a pocketbook can help cadres provide accurate information.

AIM: This study was conducted to determine the effect of the family planning pocketbook on the knowledge and skills of cadres in changing the couple’s perception about family planning.

METHODS: The research design was pre-experimental with a one-group pre-test–post-test approach. The research population was 186 people who were the representatives of family planning cadres from Bantul and Yogyakarta city. The sampling technique was performed random sampling, and 90 cadres were selected. The data were analyzed using Mann–Whitney U-Test because the data not normal distributed.

RESULTS: The results demonstrated that the knowledge and skill cadres were higher after receiving the family planning pocketbook with p < 0.05. There is an effect of the pocketbook on family planning services in the JKN era on cadres’ knowledge about the family planning program.

CONCLUSION: The family planning pocketbook affects cadre’s knowledge and skills in changing couples of childbearing age perceptions about family planning.
Influence Oxytocin Massage on Reduce Lactation Problems and Support Infants Growth
Authors: Lestari Prasetya , Fatimah Fatimah , Ayuningrum Lia , Herawati Herni Dwi , Afifaturrohmah Nisrina
Published: April 2022

Background: Lactation problems often occur in the early postnatal period. One of them is the readiness of the mother in early breastfeeding.  Early breastfeeding is one of the effective efforts in providing nutrition for newborns and preventing lactation problems. In 2019, in Indonesia, the percentage of newborns who received early breastfeeding was 75.58%. The success rate of this is closely related to lactation readiness in early postpartum. To support the success of lactation, postpartum mothers need to be given education on methods to stimulate milk production at the beginning of the puerperium with oxytocin massage. Good breast milk production will support the nutritional adequacy of the baby and reduce lactation problems in the early postpartum period.  Objectives: the purpose of this study was to determine the effectiveness of oxytocin massage on lactation problems and infant growth.  Methods: This study was pre-experimental research using posttest only design and true-experiment using posttest only control group design. The research locations were in the Mother and Child Health Clinic and Midwives Independent Practice (PMB) in Bantul, Sleman, and Gunung Kidul Yogyakarta. Implementation from April until September 2020. The population of this study was all the families of postpartum mothers from the first to the third day and after 1 week an evaluation of breastfeeding. The sampling technique uses total sampling was 80 postpartum mothers on the first-third day of childbirth until the baby was 2 months old. The research instruments were the oxytocin massage checklist, lactation problems, and body length observation sheet. Test analysis using Wilcoxon.   Results: The results of this study were that the majority of respondents performed oxytocin massage with a frequency more than 3 times (51%) the first week of postnatal, respondents experienced lactation problems in the first week of postnatal by 16.3% and at the 4th postnatal visit all respondents had no lactation problems. The average increase in the length of the baby's body at the age of 2 months is 8.44. The majority of the baby's body length at the age of 2 months corresponds to age (98.8%). The results of bivariate analysis of oxytocin massage were effective in reducing lactation problems (p=0.000) and supporting infants' growth (p=0.000).  Conclusion: Oxytocin massage is effective in reducing lactation problems and supporting infants' growth. Oxytocin massage should be implemented in postnatal care to prevent lactation problems and support breastfeeding.
The Effectiveness of Red Betel Leaf and Cinnamon Oil for Antibacterial and Anti-inflammatory in Perineal Tears: A Scoping Review
Authors: Alfiana Ratih Devi , Mulyaningsih Sundari , Emelda Emelda , Paramita Dyah Pradnya , Delia Amanah Rahma , Salsabila Shofi
Published: April 2022

BACKGROUND: A tear in the perineum experienced by postpartum women can occur due to an episiotomy process or a spontaneous tear. This cloak, in addition to causing curiosity, can also cause infection if not treated or treated appropriately. Based on several research results, the current treatment for perineal tears is the administration of antiseptic, anti-pain, and antibiotics orally or topically. Several Indonesian herbal plants can be used to accelerate the healing of torn wounds in the perineum due to the ability of these plants as antibacterial and anti-inflammatory. These plants include red betel leaf and cinnamon oil. AIM: The objective of the study was to review the literature from research results that discuss the activity of red betel leaf and cinnamon oil as antibacterial and anti-inflammatory both orally and topically. SEARCH METHOD: Searching for articles through databases on Google Scholar, in the past years, that is, 2008–2021. INCLUSION: Review articles involving research on experimental animals with in vitro and in vivo activity tests using the Completely Randomized Design method. RESULTS: As well as, 12 relevant articles showed that both red betel leaf and cinnamon oil were tested in vitro and in vivo, showing that these two plants effectively act as antibacterial and anti-inflammatory. CONCLUSION: Two herbal plants red betel leaf and cinnamon oil have the potential to treat and accelerate the healing of perineal tears through their antibacterial and anti-inflammatory activities.
Living in a changing world: Physiological and behavioural flexibility of juvenile Garden Dormice
Authors: Giroud Sylvain , Habold Caroline , Vetter Sebastian , Painer Johanna , Four-Chaboussant Anouck , Smith Steve , Gilbert Caroline
Published: April 2022

Heterothermy, or torpor, allows individuals to save energy by active reduction of metabolism and decreased body temperature. Social thermoregulation or huddling allows individuals to minimize energy needs while maintaining a relatively high body temperature. The Garden Dormouse (Eliomys quercinus), a highly endangered European rodent, uses both strategies of torpor and huddling, which are particularly beneficial for young individuals to cope with environmental fluctuations. Since juveniles are an important component of population renewal, determining the flexibility of energy-saving strategies and its consequences on somatic integrity of young individuals is key to protecting this species. We measured individual torpor patterns, body mass gain and structural growth, and assessed telomere dynamics in male and female juvenile Garden Dormice according to housing condition (singly or groups of four individuals) and food availability (fed ad-libitum or energy-limited) before and during hibernation. During development, juveniles used more frequent, longer and deeper torpor when housed singly than in groups. Torpor was encouraged by lower food availability. Juveniles showed similar body mass gain and growth, irrespective of experimental conditions. During hibernation, huddling dormice showed similar hibernating patterns and mass loss compared to single individuals regardless of food availability. Telomere lengthened across all individuals before hibernation, with larger elongation in males, which also experienced greater telomere loss than females during hibernation. We conclude that the use of torpor and huddling allows juvenile Garden Dormice to cope successfully with energetic bottlenecks, without major effects on somatic integrity. Future studies will need to confirm such findings under natural environmental conditions.
Characteristics of underground shelters used by the Edible Dormouse (Glis glis) in its European range.
Authors: Marchewka Anna , Postawa Tomasz
Published: April 2022

In response to the seasonally changing environment, mammals have developed a number of strategies that allow them to adapt to and avoid unfavourable weather conditions, along with the food shortages they often bring. In both cases, the selection of an appropriate shelter allows them to reduce their energy expenditure and to diminish the risk of suffering predation. Underground habitats, both natural (cave) and artificial (tunnels, bunkers, mines, cellars), differ in morphology (depth, length), substrate type and their connectivity with the exterior. In each underground shelter, zones can be distinguished as differing in light, humidity, and temperature that cause microclimate differentiation and determine potential habitat quality. Edible Dormice are considered a thermophilic species that prefers warm daily shelters during their active period. However, information from people exploring underground in both natural and artificial sites, indicates that this species is very common there. Here, we analyzed the data available from scientific and popular journals, speleological periodicals, website resources (such as iNaturalist), speleological websites, and personal contacts. Each find was characterized by the underground parameters: length, depth, location, and average yearly temperature. We identified more than 150 underground shelters, with morphological and thermal diversity, inhabited by this species across its range. These results indicate that underground, despite being a challenging environment, is potentially an important refuge for this arboreal species even during its active period.
Effectiveness of 6-month Use of Secukinumab in Patients With Psoriatic Arthritis in the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry
Authors: Mease Philip J. , Blachley Taylor , Dube Blessing , McLean Robert R. , Kim Nina , Hur Peter , Ogdie Alexis
Published: April 2022

Objective.

To evaluate clinical and patient-reported outcomes (PROs) at 6 months after secukinumab initiation in US patients with psoriatic arthritis (PsA).

Methods.

Patients with PsA in the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry who initiated secukinumab between April 1, 2017, and December 2, 2019, and maintained secukinumab at their 6-month follow-up visit were included. Achievement of minimal disease activity (MDA) among patients not in MDA at initiation; resolution (ie, no evidence) of tender and swollen joint counts, enthesitis, and dactylitis among patients with ≥ 1 of these at initiation; and change in disease activity and PROs were evaluated at 6 months in all patients and in patients who received secukinumab as a first-line biologic.

Results.

Of the 100 eligible patients included, most (83.0%) were biologic experienced and 17.0% initiated secukinumab as a first-line biologic. At initiation, 75/90 patients (83.3%) with available data were not in MDA; 26/71 (36.6%) with follow-up data achieved MDA at 6 months. Further, 28/68 patients (41.2%) with ≥ 1 tender joint, 24/54 (44.4%) with ≥ 1 swollen joint, 17/28 (60.7%) with enthesitis, and 9/12 (75.0%) with dactylitis at initiation achieved resolution at 6 months. Improvements in clinical manifestations, PRO measures, and work productivity and activity were observed after 6 months among patients with PsA who initiated and maintained secukinumab.

Conclusion.

In this real-world population, patients with PsA who received and maintained secukinumab for 6 months achieved MDA in proportions consistent with clinical trials and demonstrated improvements in clinical manifestations and PROs.
Monitoring of Disease Activity With a Smartphone App in Routine Clinical Care in Patients With Axial Spondyloarthritis
Authors: Kempin Robin , Richter Jutta G. , Schlegel Anna , Baraliakos Xenofon , Tsiami Styliani , Buehring Bjoern , Kiefer David , Braun Juergen , Kiltz Uta
Published: April 2022

Objective

To investigate the performance of a health app with respect to usability, adherence, and equivalence of data in daily care of patients with axial spondyloarthritis (axSpA).

Methods

Consecutive patients with axSpA were asked to export patient-reported outcomes (PRO) electronically with the AxSpA Live App regularly every 2 weeks over a period of 6 months. The first clinical visit was followed by 2 further personal visits after 3 and 6 months. Patients completed paper-based PRO at every visit; they also completed the Mobile App Rating Scale and the System Usability Scale after 3 and 6 months.

Results

Of 103 patients with axSpA, 69 agreed to participate (67.0%): age 41.5 (11.3) years, 58.0% male, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) 4.3 (2.0), and 76.8% treated with biologic disease-modifying antirheumatic drugs. Patients’ adherence to regular app exports was 29.0% and 28.4% after 3 and 6 months, respectively. Significant predictors for good adherence were high disease activity (P = 0.02) and older age (P = 0.04). No systematic differences between digital and paper-based BASDAI scores were found (intraclass correlation coefficients 0.99 [95% CI 0.98-0.99]). Performance of the app was rated as good.

Conclusion

Collection of digital PROs by AxSpA Live App may be successfully used in patients with axSpA with high disease activity. Our study showed equivalence of digital data, but adherence to the app after 6 months was poor. Higher disease activity and older age resulted in increased adherence to the app. This suggests that the use of health apps like this should concentrate on more severely affected patients.
Geriatric functional assessment for decision-making on adjuvant chemotherapy in older colon cancer patients
Authors: Bang Hyun Jin , Shim Hyun Jeong , Kim Ga Ram , Hwang Jun Eul , Bae Woo Kyun , Chung Ik Joo , Cho Sang Hee
Published: April 2022

Background/Aims: Despite the increasing need for geriatric assessment prior to chemotherapy, the method for this assessment remains inadequate for older cancer patients. We aimed to propose a simple assessment method to predict the performance of adjuvant chemotherapy in older patients after colon cancer surgery.Methods: This prospective study included patients over 65 years of age who were scheduled for adjuvant chemotherapy after colon cancer surgery. Before initiating chemotherapy, their functional status was assessed on the basis of activities of daily living (ADL)/instrumental activities of daily living (IADL). These parameters were analyzed with clinical characteristics and the patterns of adjuvant chemotherapy. The focus was on the completion rate of adjuvant chemotherapy.Results: A total of 89 patients with a median age of 72 years were analyzed. Among them, 54 (61%) were non-impaired and 35 (39%) were impaired regarding their ADL/IADL classification. Low body mass index and impairment of ADL/IADLs were significantly associated with chemotherapy interruption. Among toxicities, fatigue and hand-foot syndrome were independent prognostic factors for chemotherapy interruption. Impairments of ADL/IADL were significantly associated with fatigue regardless of age. Based on age and ADL/IADL stratification, younger patients (≤ 72 years) and/or those who were ADL/IADL non-impaired were significantly more likely to complete adjuvant chemotherapy than older patients (> 72 years) and ADL/IADL impaired patients (p = 0.038). This was regardless of the chemotherapy regimen.Conclusions: Functional assessment using ADL/IADL is a convenient method to predict chemotherapy toxicity and performance. These results suggested that routine screening for ADL/IADLs could guide appropriate patient selection for the completion of adjuvant chemotherapy and predict expected outcomes.
« Où sont les femmes ? » Dimension spatiale d’une action collective de femmes dans les cafés d’Aubervilliers
Authors: Blanchard Sophie , Chapuis Amandine
Published: April 2022

À partir de la monographie de l’action militante d’un collectif féministe, cet article entend croiser géographie du genre et géographie des mouvements sociaux pour montrer comment les rapports de genre s’articulent avec les logiques du changement urbain. Le texte interroge la mobilisation d’un collectif de femmes en faveur de la mixité dans l’espace public et en particulier dans les cafés. Appuyée sur une enquête par observation participante et entretiens, cette recherche documente la dimension spatiale de cette mobilisation, mettant en évidence le rôle de l’espace dans les répertoires de l’action collective. Elle interroge les échelles du militantisme, soulignant sa dimension multiscalaire, entre ancrage local et projection globale. L’article analyse enfin l’articulation de cette action collective avec les dynamiques de gentrification qui caractérisent la commune d’Aubervilliers, à travers la compréhension de la manière dont les trajectoires des membres du Collectif dessinent les normes d’une citadinité renouvelée qui entrent parfois en tension avec certains usages populaires des espaces publics de la ville.