bluuebunny/crossref_metadata_2025 huggingface dataset:
Normal ESR, CRP and Platelet Count in Giant Cell Arteritis and Polymyalgia Rheumatica: A Diagnostic Conundrum
Authors: Elsheikh Mahgoub Abdullahi , Tessema Sophia , Nakhleh Rasha
Published: February 2022

Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are both rheumatological diseases of the elderly with a strong association with each other and which rarely present with normal inflammatory markers. Here we present the case of a 61-year-old Caucasian woman who had typical symptoms of both diseases. At the time of presentation, her blood work showed normal inflammatory markers, but because of the high clinical suspicion for GCA, a temporal artery biopsy was done which was positive for giant cells and disruption of the internal elastic lamina. Our patient responded very well to treatment with oral steroids and steroid-sparing medication and was able to return to her normal life without experiencing any complications of the disease. By sharing our case, we aim to increase the awareness of medical personnel regarding the importance of focusing on the clinical presentation as well as the laboratory and pathological aspects of diagnosing GCA and PMR.
Klinik Penyusunan Rencana Program Pembelajaran (RPP) dan Pelatihan TIK bagi Guru Pos PAUD Terpadu (PPT) Mawar di Surabaya
Authors: Hariadi Victor , Buliali Joko Lianto , Saikhu Ahmad , Purwananto Yudhi , Amaliah Bilqis , Wijaya Arya Yudi
Published: February 2022

Pendidikan Anak Usia Dini (PAUD) merupakan pondasi awal bagi pertumbuhan dan perkembangan selanjutnya. Ontologis anak sebagai makhluk mempunyai aspek biologis dan psikologis. Pembelajaran pada anak usia dini haruslah menggunakan konsep belajar melalui bermain, belajar sambil berbuat, serta melalui stimulasi PAUD berdasarkan aspek pedagogis. Dari segi empiris PAUD sangat penting, antara lain menjelaskan bahwa pada waktu manusia lahir, kelengkapan organisasi otak memuat 100-200 milyar sel otak yang siap dikembangkan serta diaktualisasikan mencapai tertinggi. Selain itu tujuan PAUD yang ingin dicapai adalah mengembangkan pengetahuan dan pemahaman orang tua dan guru serta pihak-pihak yang terkait dengan pendidikan dan perkembangan anak usia dini. Oleh karenanya sangat penting bagi guru-guru PAUD untuk senantiasa mengevaluasi dan memperbaharui kurikulum dan metode pengajaran kepada anak-anak usia dini ini. Selain melalui pemahaman dan pengaplikasian penduan yang dibuat oleh dinas pendidikan setempat, juga yang tidak pentingnya adalah berdiskusi dan memahami perkembangan teknologi informasi terkini, baik dijadikan sebagai sisipan bahan ajar, maupun sebagai perangkat bantu pengajaran. Dalam pelaksanaan kegiatan pengabdian kepada masyarakat ini akan dilaksanakan diskusi penyusunan Rencana Program Pembelajaran (RPP) serta pelatihan Teknologi Informasi dan Komunikasi (TIK) yang dapat dimanfaatkan sebagai media pembelajaran kepada anak-anak usia dini. Diharapkan melalui kegiatan ini guru-guru PAUD dapat mengikuti perkembangan teknologi terkini serta dapat meningkatkan kualitas pembelajaran kepada siswa-siswa PAUD yang diasuhnya
Aplikasi Eco Enzyme Sebagai Bahan Pembuatan Sabun Antiseptik
Authors: Jadid Nurul , Jannah Adillatul Lathiifatun , Wicaksono Putra Handiar Bagas Prakoso , Nurhidayati Tutik , Purwani Kristanti Indah , Ermavitalin Dini , Muslihatin Wirdhatul , Navastara Ardy Maulidy
Published: February 2022

Indonesia merupakan negara tropis dan agraris dengan biodiversitas tumbuhan terbesar kedua di dunia, setelah Brazil. Kondisi iklim tropis dan suburnya tanah menjadikan wilayah Indonesia sebagai salah satu Kawasan pertanian yang diperhitungkan di wilayah asia tenggara. Salah satu sentra agribisnis di Jawa Timur adalah kota Batu, Malang. Kota ini dikenal sebagai Kawasan Agropolitan dengan tanaman hortikultura sebagai komoditas unggulan. Industri pertanian dan perkebunan di wilayah tersebut berhasil menopang ekonomi masyarakat sekitar. Namun demikian, permasalahan limbah pertanian organik sebagai produk samping dari pengembangan industri pertanian di kota Batu menjadi hal yang harus diperhatikan bersama. Salah satu alternatif pengelolaan limbah atau sampah organik tersebut adalah pengembangan eco-enzyme. Kegiatan pengabdian masyarakat ini berupa pembuatan sabun antiseptic berbasis eco-enzyme. Sabun antiseptic ini mengambil nama Mizella yang berasal dari kata Mizu dan Ella. Mizu dalam Bahasa Jepang berarti Air dan Ella dalam Bahasa Prancis berarti kecantikan dan keindahan. Berdasarkan hasil survei didapatkan hasil sebagai berikut, sebanyak 80% responden menyatakan aroma, busa, kelembapan, kesegaran, pada sabun organik sudah sangat baik, sebanyak 73.3% responden menyatakan warna, penampilan, busa pada sabun organik Eco-Enzyme sudah sangat baik, sebanyak 76.7% responden menyatakan kualitas pembersihan dan kekesatan pada sabun organik Eco-Enzyme sudah sangat baik, sebanyak 83.3% responden menyatakan kehalusan pada sabun organik Eco-Enzyme sudah sangat baik.
Desain Bisnis Herbal (Minyak Atsiri dan Madu AMKE) Pasca Produksi dalam Upaya Pengabdian kepada Masyarakat Desa Oro-Oro Ombo, Kota Batu
Authors: Nurhayati Awik Puji Dyah , Sa’adah Noor Nailis , Setiawan Edwin , Navastara Dini Adni , Rosdiana Lissa , Prasetyo Didit
Published: February 2022

Desa Oro-oro Ombo memiliki letak yang strategis di dekat Kota Batu dengan kondisi iklim yang sangat mendukung untuk pertanian tanaman herbal. Semakin bertambahnya waktu, terjadi penurunan minat konsumen terhadap produk produk herbal. Penyebab utama terjadinya fenomena ini adalah produk herbal memiliki masa kadaluarsa yang lebih cepat, kemasan yang kurang efektif dan efisien, serta kurangnya promosi sehingga tidak banyak masyarakat yang mengetahui keunggulan suatu produk herbal. Maka dari itu perlu adanya rancangan bisnis untuk meningkatkan nilai jual suatu produk herbal melalui video promosi dan juga pembaruan kemasan dan label. Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah peningkatan mutu produk herbal dalam bidang kesehatan dan perekonomian. Proses kegiatan ini dilakukan dengan membuat Business Model Canvas untuk mengorganisir dan mengontrol jalannya suatu bisnis, kemudian pengembangan upaya promosinya dilakukan dengan iklan berupa video untuk mengenalkan produk herbal AMKE seperti madu serta minyak atsiri roll on} dan gantungan mobil. Hasil dari kegiatan pengabdian kepada masyarakat ini adalah sebuah luaran berupa video promosi dan juga desain produk beserta kemasan yang baru bagi produk madu, minyak atsiri roll on, dan gantungan mobil.
Student Performance Prediction Model for Predicting Academic Achievement of High School Students
Authors: Nuankaew Pratya , Nuankaew Wongpanya Sararat
Published: February 2022

Modern technology is necessary and important for improving the quality of education. While machine learning algorithms to support students remain limited. Thus, it is necessary to inspire educational scholars and educational technologists. This research therefore has three main targets: to educate the holistic context of rural education management, to study the relationship of continuing education at the upper secondary level, and to construct an appropriate education program prediction model for high school students in a rural school. The data for research is the academic achievement data of 1,859 students from Manchasuksa School at Mancha Khiri District, Khon Kaen Province, Thailand, during the academic year 2015-2020. Research tools are separated into 2 sections. The first section is a basic statistical analysis step, it composes of frequency analysis, percentage analysis, mean analysis, and standard deviation analysis. Another section is the data mining analysis phase, which consists of discretization technique, XGBoost classification technique (Decision Tree, Gradient Boosted Trees, and Random Forest), confusion matrix performance analysis, and cross-validation performance analysis. At the end, the research results found that the reasonable distribution level of student achievement consisted of four clusters classified by academic achievement. All four clusters were modeled on predicting academic achievement for the next generation of students. In addition, there are four success models in this research. For future research, the researcher aims to develop an application to facilitate instruction for learners by integrating prediction models into the mobile application to promote the utilization of modern technology.
New Erodibility Parameterization for Applying WEPP on Rangelands Using ERMiT
Authors: Al-Hamdan Osama Zuhair , Pierson Fred B. , Robichaud Peter , Elliot William J. , Williams Christopher Jason
Published: February 2022

Highlights

A practical parameterization approach to estimate erodibility was developed for WEPP applications on rangelands.

Soil texture had a greater effect on rill erodibility than vegetation cover.

Vegetation cover had a greater effect on interrill erodibility than soil texture.

A new set of erodibility input parameters was defined for ERMiT applications on rangelands.

Abstract. The USDA Water Erosion Prediction Project (WEPP) is a process-based soil erosion prediction model. WEPP uses three soil erodibility parameters: rill erodibility (Kr), interrill erodibility (Ki), and critical hydraulic shear stress (tc). In this study, a new parameterization approach for estimating erodibility was developed for WEPP applications on rangelands. Data from overland flow experiments on disturbed and undisturbed rangelands were used to develop empirical equations to predict rill erodibility variation as a function of vegetation cover and soil texture. Data from rainfall simulation experiments were analyzed by piecewise regression to develop empirical equations for predicting the variability of interrill erodibility before and after disturbance and across a wide range of soil textures as a function of vegetation cover and soil texture. Critical shear values corresponding to the developed rill and interrill erodibility parameters were proposed. Our results show that the new erodibility approach predicts erosion at the plot scale with a satisfactory range of error (PBIAS =35.6 and Nash-Sutcliffe efficiency = 0.49). The new approach was used to provide soil erodibility values for the Erosion Risk Management Tool (ERMiT), which uses WEPP as the runoff and erosion calculation engine. Keywords: ERMiT, Erosion, Interrill, Rangeland management, Rill, Shrub, Soil burn severity, WEPP.
Bioinspired Imbricated Microthorn Scale Surfaces and their Abrasive Wear Performance
Authors: Zhang Zhihong , Yuan Shuo , Lai Qinghui , Zuo Guobiao , Guler Huseyin
Published: February 2022

Highlights

Improving the wear resistance of soil-engaging components is an urgent need for the agricultural machinery industry.

Sandfish (Scincus scincus) epidermis with exceptional wear resistance was selected as a bionic prototype.

By adopting a bionic engineering approach, a novel bioinspired microthorn scale surface was designed and prepared.

Numerical simulations were performed with EDEM to investigate the wear resistance mechanism.

Abstract. To solve the problem of abrasive wear failure of the soil-engaging components of agricultural machinery, the imbricated microthorn scale structure of the sandfish (Scincus scincus) epidermis surface was selected as a bionic prototype. By adopting a bionic engineering approach, nine bionic microthorn scale surface specimens with different geometric structure parameters were designed and prepared. Wear resistance tests were performed in a rotating abrasive wear testing system. The results of the wear tests showed that the imbricated microthorn scale structured surfaces had substantially less abrasion loss than a conventional smooth surface. The influence of the geometric structure parameters on the wear performance was also identified. Numerical simulations were performed to explore the wear resistance mechanism of the imbricated microthorn scale structured surfaces. The abrasion of the bionic surfaces mainly occurred at the edge of the microthorn that faced the abrasive particle flow. The trajectory of subsequent abrasive particle flow was modified by the large dispersion of particle flow; hence, the number of particles that impacted the surface decreased. Therefore, the wear resistance performance of the bionic surfaces was enhanced. This bioinspired surface can provide a technical reference to mitigate the abrasive wear failure of the soil-engaging components of agricultural machinery. Keywords: Abrasive wear, Archard wear, Bionic design, Discrete element method, Scale surface.
Sugarcane wax extraction using hexane and limonene mixtures
Authors: Silva Gabriel Julio da , Henriques Julcelly Dayara de Oliveira , Martinez Patricia Fazzio Martins
Published: February 2022

Hexane is the most widely solvent used in the lipids extraction process, as the case of the sugarcane wax. However, the use of this solvent is highly harmful to the environment and to human health. Limonene is a monoterpene found in the citrus peel, with great potential for use as a green solvent. In this study, the partial and total substitution of hexane by limonene was performed in the process of the sugarcane peel wax extraction to evaluate the effect of this substitution on the physicochemical characteristics of the wax. The extracted samples were compared with a commercial wax sample (carnauba) using the Thermogravimetric Analysis (TGA), Differential Scanning Calorimetry (DSC) and Infrared by Fourier Transform (FTIR) analyses. Through this study, we can conclude that the waxes obtained from the use of the hexane and limonene mixture solvents presented similar physicochemical characteristics to those found in commercial waxes. Thus, the total and/or partial substitution of the hexane by solvents less harmful to health and the environment, such as limonene, can be an alternative in the wax extraction process.
Desde el compromiso social hasta el desarrollo sostenible: desafíos docentes de una educación universitaria de calidad transformadora
Authors: Durán Ayago Antonia
Published: February 2022

Docencia, Universidad, responsabilidad social, Objetivos de Desarrollo sostenible y compromiso ético encuentran acomodo en la metodología docente del aprendizaje-servicio, método que está llamado a desempeñar un papel cada vez más importante en la formación de nuestros estudiantes universitarios. En este trabajo se aportan las principales notas características de este método y algunas claves sobre cómo orientar esfuerzos a la consecución de los ODS partiendo de la experiencia de la Clínica Jurídica de Acción Social de la Universidad de Salamanca.
Colaboración en un programa de ética profesional entre un colegio de profesionistas y una universidad: una experiencia en México
Authors: Gallardo Yurixhi , Torres Romero Alexa Guadalupe
Published: February 2022

El trabajo tiene por objetivo mostrar una experiencia de colaboración entre un colegio de profesionistas de Derecho en México y académicos de una institución de educación superior en el diseño e implementación de un programa para la enseñanza de la Ética Profesional a estudiantes de licenciatura en una universidad del occidente de México. Esta actividad se llevó a cabo en el marco de difusión de los Objetivos de Desarrollo (ODS) 4, 5, 16 y 17. La metodología utilizada fue el planteamiento y solución de dilemas éticos elaborados a partir de las experiencias de los profesionales del colegio. El artículo está dividido en tres apartados: el primero explica la importancia de la enseñanza de la ética profesional a partir del cuarto ODS y la necesidad de su incorporación a los programas de estudio de la licenciatura en Derecho que contribuyan a lograr el ODS número 16; el segundo aborda la experiencia del desarrollo de casos prácticos de ética llevados a cabo en un colegio de profesionistas; por último, se analiza la experiencia de la implementación de dicho programa en una universidad del occidente de México. La experiencia muestra los resultados al utilizar situaciones planteadas por profesionistas para la formación en ética profesional a los integrantes del colegio y a los estudiantes de la licenciatura.
Análisis de los Premios Nacionales Vicente Ferrer como instrumento para alcanzar el objetivo nº4 del Desarrollo Sostenible
Authors: Pérez Curiel María Jesús , Martín Rivas Dunia , Francisco Fernández Alejandrino
Published: February 2022

La investigación ‘Análisis de los premios nacionales Vicente Ferrer como instrumento para alcanzar el objetivo nº4 del Desarrollo Sostenible’ pretende estudiar las dimensiones actuales del concepto de Educación para el Desarrollo Sostenible, profundizar sobre su pedagogía y mostrar la implicación de los centros educativos españoles y sus docentes en la Educación para el Desarrollo a través de los galardones Vicente Ferrer. Tras haber encuestado a 174 docentes y analizado los datos obtenidos, se infiere que la implantación de la Educación para el Desarrollo en las aulas españolas se ha conseguido realizar de una forma eficaz y eficiente hasta el momento. Además, los datos indican que los docentes están cada vez más cualificados en esta materia pero pocos han visto premiado su esfuerzo. Sin embargo, el texto destaca que es imprescindible que, antes de incorporarse a la docencia, los futuros maestros y profesores cuenten con una Educación Superior que les aporte las herramientas necesarias para incorporar competencias vinculadas a la Educación para el Desarrollo Sostenible en las aulas.
Multi-focus image fusion algorithm based on random features embedding and ensemble learning
Authors: Zuo Jinnian , Zhao Wenhao , Chen Li , Li Jun , Du Kai , Xiong Liang , Yin Shaoyun , Wang Jinyu
Published: February 2022

Multi-focus image fusion algorithm integrates complementary information from multiple source images to obtain an all-in-focus image. Most published methods will create incorrect points in their decision map which have to be refined and polished with post-processing procedure. Aim to address these problems, we present, for the first time, a novel algorithm based on random features embedding (RFE) and ensemble learning which reduced the calculation workload and improved the accuracy without post-processing. We utilize RFE to approximate a kernel function so that Support Vector Machine (SVM) can be applied to large scale data set. With ensemble learning scheme we then eliminate the abnormal points in the decision map. We reduce the risk of entrap into over-fitting predicament and boost the generalization ability by combining RFE and ensemble learning. The theoretical analysis is in consistence with the experimental results. With low computation cost, the proposed algorithm achieve high visual quality as the state-of-the-art(SOTA).
Optical anisotropy of glancing angle deposited thin films on nano-patterned substrates
Authors: Grineviciute Lina , Moein Tania , Han Molong , Ng Soon Hock , Anand Vijayakumar , Katkus Tomas , Ryu Meguya , Morikawa Junko , Tobin Mark J. , Vongsvivut Jitraporn , Tolenis Tomas , Juodkazis Saulius
Published: February 2022

This study has demonstrated that 3D columnar micro-films/coatings can be deposited over pre-patterned surfaces with sub-micrometer periodic patterns. Four-angle polarisation analysis of thin (0.4 − 1~μm) Si and SiO2 films, evaporated via glancing angle deposition (GLAD) at 70° to the normal, was carried out in reflection mode using synchrotron infrared microspectroscopy at the Australian Synchrotron. The angular dependence of absorbance followed A(θ) ∝ cos 2θ, confirmed for Si substrates patterned by electron beam lithography and plasma etching, which were used to make checkerboard patterns of Λ = 0.4~μm period on Si. Retardance control by birefringence of a patterned SiO2 substrate coated by columnar SiO2 is promising for UV-visible applications due to the use of the same material to endow polarisation control.
The status of schistosomiasis japonica control in the Philippines: The need for an integrated approach to address a multidimensional problem
Authors: Belizario Vicente Y. , Jr. , de Cadiz Aleyla E. , Navarro Rohani C. , Flores Mary Jane C. , Molina Victorio B. , Dalisay Soledad Natalia M. , Medina John Robert C. , Lumangaya Carlo R.
Published: February 2022

Schistosomiasis japonica remains a public health concern in many areas of the Philippines. Adequate and updated information is essential to enhance policy and service delivery toward control and elimination. Despite the efforts on schistosomiasis control in the Philippines, some challenges remain in these dimensions. An integrated surveillance system is recommended to determine the prevalence of infection in humans, animal reservoirs, and snail intermediate hosts, allowing the identification of high-priority areas for targeted interventions. This will entail the enhancement of laboratory diagnosis capacity through the use of more sensitive techniques, complemented by capacity building of concerned human and animal health professionals. Given the zoonotic nature of schistosomiasis japonica, adopting the One Health approach is essential to influence policies and interventions that may accelerate control and elimination. This can be achieved through the attainment of mass drug administration coverage targets and intensified case finding and management, robust implementation and integration of veterinary public health activities, the conduct of snail control measures, provision of safe water, sanitation, and hygiene services, and health promotion and education into the national schistosomiasis control and elimination program. This review aimed to describe the status of schistosomiasis japonica control in the Philippines in the context of human health, animal health, vector ecology and management, environmental health, and sociocultural dimensions.
From Hollywood mobster to Russian gangster: representations of mafia in Coppola’s Godfather trilogy and Balabanov’s Brother films
Authors: Olszowska Lara Hania
Published: February 2022

This study examines the changed mythology of crime in the Hollywood gangster genre resulting from new representations of mafia in Francis Ford Coppola’s Godfather trilogy. The trilogy will be viewed as a point of departure for new experimentations in the gangster genre in response to the Russian experience of mafia, namely in Aleksei Balabanov’s Brother film sequence. This analysis will discuss the key themes that appear in Coppola’s trilogy including family, masculinity, morality, and identity and consider the extent to which they either translate to or mutate in Balabanov’s sequence. This research will also explore how Balabanov infuses his films with unique Russian stylistic elements from the bylina (fairy-tale) and aesthetics from chernukha (dark cinema) in order to create a reimagined version of the gangster film. This consideration of the filmic depictions of mafia does not attempt to define the mafia in its truly existing form but seeks to understand how two different experiences of mafia and their interpretations can compare on screen, and how this reveals the tension between resisting and accepting the influence of Hollywood and America on Russian cinema and society.
Risks for development of metabolic disorders in alimentary constitutional obesity
Authors: Lyasnikova M. B. , Belyakova N. A. , Tsvetkova I. G. , Rodionov A. A. , Milaya N. O.
Published: February 2022

BACKGROUND: alimentary-constitutional obesity due to it’s high prevalence, is the key problem of modern healthcare system. However, obesity is not always accompanied with metabolic disorders, leading to early invalidization and mortality. That’s why it is important to study risks of metabolical nonhealth in obesity.

AIM: to detect factors, increasing risks of development of metabolic disbalance in alimentary-constitutional obesity.

MATERIALS AND METHODS: In patients with alimentary-constitutional obesity there was performed an examination including anthropometry (body mass index, Waist Circumference, Hip Circumference,waist to hip ratio), blood pressure measurement, laboratory tests – metabolic indexes: glucose, insulin, insulin resistance indexes, leptin, cholesterol, cholesterol of lipoproteins, triglycerides, aspartate aminotransferase, alanine aminotransferase, gamma-glutamiltransferase), body composition measurement by bioelectrical impedance analysis; patients were also interviewed on their behavior (food habits) and physical activity.

RESULTS: There were formed two groups depending on metabolic health indexes: main group – metabolically non-healthy obesity (MNHO) - 241 persons (aged 41±12,09, duration of obesity 12,5±9,51 years) with alimentary-constitutional obesity and two or more signs of MS, a comparison group – of metabolically healthy obesity (MHO) – 120 persons (aged 35,5±10,03; p<0,05, duration of obesity 8,0±7,39 years; p<0,05) with alimentary-constitutional obesity and one sign of MS or without it. Data analysis of studied risk factors for development of metabolically non-healthy alimentary-constitutional obesity confirmed that most relevant factor in development of MNHO is abdominal fat mass distribution (increasing of Waist Circumference over 88 sm in females and over 102 sm in mails). At the same time MNHO had correlation not only with classical signs of MS, but also with blood insulin level, insulin resistance indexes, fat metabolism disbalance and liver disfunction. More severed risk for appearance of metabolic disorders have patients over 45 years old with decreased active cell mass (less than 45%), duration of obesity above 10 years and obesity-burdened heredity. In food habits risk of development of metabolically non-healthy obesity was increased in taking of fat milk food, and, on the contrary, - frequent snacks, alcohol free sweet drinks didn’t affect it.

CONCLUSION: Development of MNHO is associated not only with the age of patient, duration of obesity, carbohydrate and fat metabolism indexes, but also with decreased percentage of metabolically active tissues and some food habits.
Enchanced preoperative rehabilitation as part of the complex perioperative rehabilitation of patients with super-obesity and obstructive sleep apnea syndrome (clinical outlook)
Authors: Orlovskaya E. S. , Achkasov E. E. , Yashkov Yu. I. , Zorin E. A. , Ermakov N. A.
Published: February 2022

Obesity is a global social and economic problem. The bariatric surgery is a most effective treatment for obesity. The presented clinical case demonstrates the usage of principles of enchanced perioperative rehabilitation for the preoperative preparation of a patient with super obesity and with severe obstructive sleep apnea and alveolar hypoventilation syndrome.

A 54-year-old patient was hospitalized with complaints of obesity, impossibility of persistent weight loss conservatively, severe daytime sleepiness, frequent nocturnal awakenings (up to 8 times per night). The patient’s weight was 230 kg with a height of 157 cm (BMI 93.5 kg / m2). The examination revealed a syndrome of sleep apnea of mixed genesis of extremely severe degree, chronic night hypoxemia of an extremely severe degree. Preoperative preparation was performed in accordance with the program of enchanced perioperative rehabilitation. The duration of preoperative preparation was 19 days; weight loss — 40 kg (%WL -17,4), compensation of comorbidities was achieved as well. After that the patient underwent a laparoscopic sleeve gastrectomy. There were no complications in the postoperative period. Length of postoperative hospital stay was 6 days. At follow-up examination one year after surgery, body weight dropped from 230 to 153 kg (% WL-33.5), a significant improvement of the quality of life was achieved.

The enchanced perioperative rehabilitation program can be successfully used as an effective method for preoperartive preparation of the patients with morbid obesity in combination with severe obstructive sleep apnea syndrome.and obesity hypoventilation. It can be a reasonable alternative to the standard program with preoperative intragastric balloon treatment. The use of this technique allows to increase the effectiveness of treatment of these high-risk patients, as well as to reduce the risk of perioperative complications.
Obesity and covid-19 — signs of convergence of two pandemiсs. Guidelines to fight obesity based on the principles of «ROOTS»
Authors: Fursov A. B. , Ospanov O. B. , Fursov R. A.
Published: February 2022

The COVID-19 pandemic is a challenging problem of the present. Another essential problem causing serious health consequences is the global obesity epidemy. Our article notes the importance of studying the combinations and correlations of mentioned pandemic processes. We analyzed scientific reports of co-presence of obesity, diabetes and coronavirus infection. According to the analyzed data combination of COVID-19 with obesity and diabetes leads to the higher rate of the hospitalisation. These patients more often required the transfer to the intensive care unit and artificial lung ventilation. Our review contains scientific observations of the first reported cases of higher mortality rate of obese and diabetic patients during the period of previous influenza pandemics (including H1N1). The results of the 2020 year shows that the outcomes of coronavirus infection with underlying obesity much more threatening and harmfull. In our article, we present the correlation of the average body mass and mortality rate index in different countries (according to the WHO and the World Obesity Federation). Comparative results in the Central Asia countries are given as well. The paper analyzes the suggestions for obesity policy and advocacy provided by World Obesity Federation in “ROOTS: A framework for action”. The conclusions marks the importance of implementing the proposed measures against obesity during a pandemic and in the post-COVID era.
Features of modeling fatty liver disease in rats of different ages based on a high-calorie diet
Authors: Yanko R. V. , Chaka E. G. , Zinchenko A. S. , Safonov S. L. , Levashov M. L.
Published: February 2022

BACKGROUND: The problem of diagnosis, treatment and prevention of fat liver disease (FLD) is one of the actual problems of modern medicine. In this regard, the need for the creation of reliable experimental models of the FLD, which would be as close as possible to the pathogenetic patterns of the development of this disease in humans.

AIM: To create an experimental model of FLD and compare the efficiency of its reproduction in rats of different ages.

MATERIALS AND METHODS: The study was conducted on male Wistar rats, whose ages at the beginning of the experiment were 3 and 18 months. Control animals were fed a standard diet. The experimental rats were kept on a diet with excess fat (45 %) and carbohydrates (31 %) for 12 weeks. The liver tissue samples were taken for morphological studies of FLD. Histological preparations were made according to the standard technique. Morphometry on digital images of micropreparations was conducted using the computer program «IMAGE J». The concentration of lipids, cholesterol, and triglecerides in the liver tissue was determined, and the concentration of ALT in the blood serum was determined. To assess the biophysical properties of the liver tissue, the method of multifrequency bioimpedance measurement was used.

RESULTS: The transfer of animals to a high-calorie diet developed by us led to the development of FLD. This was evidenced by an increase of the liver mass, its pale shade and soft consistency. Morphometric signs of FLD were also revealed. Hypertrophy of hepatocytes was observed with a simultaneous decrease in the nuclear-cytoplasmic ratio; accumulation of numerous lipid inclusions in the cytoplasm and the appearance of large lipid droplets replacing the voids of dead hepatocytes. The number of binuclear hepatocytes and nucleolus in the nucleus, the relative area of the sinusoid network were decreased. An increase in the concentration of lipids, cholesterol and triglecerides in the liver tissue of experimental rats, as well as the activity of ALT in the blood serum, was observed. Changes in the bioimpedance measurements of the liver tissue also indicated the  development of severe fatty degeneration of the liver in both young (to a greater extent) and old rats.

CONCLUSION: The model of FLD we have advanced based on a combined (fat-carbohydrate) high-calorie diet. It leads to the development of pronounced morphological, biochemical and biophysical signs of this pathology in all experimental rats. The most pronounced manifestations of FLD are observed in young animals.
High prevalence of low vitamin D levels in endocrine disorders
Authors: Pigarova E. A. , Dzeranova L. K.
Published: February 2022

BACKGROUND: Vitamin D deficiency and insufficiency are widespread medical abnormalities, but their frequency in endocrine diseases has generally not been studied.

AIM: To provide a comparative assessment of vitamin D levels in patients with diabetes mellitus type 2, primary hyperparathyroidism (PHPT), central hypercortisolism (Cushing’s disease; CD) and acromegaly.

MATERIALS AND METHODS: Total 25(OH)D was determined using the immunochemiluminescent method (the laboratory participates in the DEQAS program). All patients had GFR > 60 ml/min, no history of use of vitamin D supplementation within previous month.

RESULTS: The study included 365 patients who, after applying the inclusion/exclusion criteria, were divided into 5 main research groups: 33 patients with diabetes mellitus type 2, 23 patients with PHPT, 68 patients with CD, 22 patients with acromegaly, and 141 apparently healthy patients. Significantly low levels of vitamin D were found in patients with diabetes mellitus type 2 (14.8 ng/ml), acromegaly (14.9 ng/ml), CD (14.6 ng/ml), and PHPT (15.9 ng/ml) compared with a group of otherwise healthy patients (18.8 ng/ml).

CONCLUSION: The results of the study demonstrate a high prevalence of vitamin D deficiency not only in groups of patients with chronic diseases, but also among practically healthy patients. Further studies are needed to address the causes of high vitamin D deficiency in the described endocrine diseases.
Evaluation of the effectiveness of weight loss and the return of lost weight after sleeve gastrectomy in the long term follow-up period
Authors: Neimark A. E. , Molotkova M. A. , Kravchuk E. N. , Kornyushimn O. V.
Published: February 2022

Sleeve gastrectomy, originally proposed as part of a two-stage operation, more than 15 years ago, is recognized as an independent, effective intervention for the treatment of obesity. The purpose of this review was to evaluate the effectiveness of sleeve gastrectomy based on data on long-term follow-up of patients. A search was performed in two databases, 33 literary sources were selected based on the results of the selection. In this review, the authors evaluated some parameters characterizing the effectiveness of sleeve gastrectomy in the long term after surgery. The percentage of follow-up of patients in the long-term period (follow up, %) varied from 5,6% to 97%, the expected decrease in % follow up over time did not occur. The authors have suggested similar results due to the heterogeneity of the data of the analyzed sources. By the five-year period, the detected average % of follow-up did not correspond to the optimal recommended level of follow-up for operated patients by this time. The most common criterion for assessing the return of weight is an increase in body weight by more than 10 kg from the lowest achieved. The prevalence of this phenomenon ranged from 26.3% to 44%. Among the reasons predisposing to weight loss are the initial high BMI, old age, dilatation of the formed stomach. In the absence of a universal definition of various terms (follow up, unsatisfactory result of surgery, weight loss, etc.), the results among the same patients when using different definitions will differ, there is a need to adopt standards when describing these phenomena. Despite the likelihood of weight loss after longitudinal resection, this operation is relatively simple from a technical point of view, safer, it can be used to improve the course of concomitant pathology (diabetes mellitus, hypertension), improve the quality and increase the life expectancy of patients.
High-spatial-resolution, instantaneous passive cavitation imaging with temporal resolution in histotripsy: a simulation study
Authors: Jeong Mok Kun , Choi Min Joo , Kwon Sung Jae
Published: February 2022

Purpose: In histotripsy, a shock wave is transmitted, and the resulting inertial bubble cavitation that disrupts tissue is used for treatment. Therefore, it is necessary to detect when cavitation occurs and track the position of cavitation occurrence using a new passive cavitation (PC) imaging method.Methods: An integrated PC image, which is constructed by collecting the focused signals at all times, does not provide information on when cavitation occurs and has poor spatial resolution. To solve this problem, we constructed instantaneous PC images by applying delay and sum beamforming at instantaneous time instants. By calculating instantaneous PC images at all data acquisition times, the proposed method can detect cavitation when it occurs by using the property that when signals from the cavitation are focused, their amplitude becomes large, and it can obtain a high-resolution PC image by masking out side lobes in the vicinity of cavitation.Results: Ultrasound image simulation confirmed that the proposed method has higher resolution than conventional integrated PC imaging and showed that it can determine the position and time of cavitation occurrence as well as the signal strength.Conclusion: Since the proposed novel PC imaging method can detect each cavitation separately when the incidence of cavitations is low, it can be used to monitor the treatment process of shock wave therapy and histotripsy, in which cavitation is an important mechanism of treatment.
OCORRÊNCIA DE CÂNCER NA PRIMEIRA INFÂNCIA EM SANTA CATARINA: ANÁLISE DOS REGISTROS HOSPITALARES
Authors: Friestino Jane Kelly Oliveira , Faria Rivaldo Mauro , Guerra Paulo Henrique Araújo , Francisco Priscila Maria Stolses Bergamo
Published: February 2022

A rede de atenção oncológica deve ser norteada a partir de indicadores e de características próprias do território, fomentando a oferta de serviços condizentes com a realidade. Com isso, objetivou-se identificar a tendência temporal e os locais de atendimento de câncer na primeira infância, segundo macrorregiões do estado Santa Catarina, entre os anos de 2009 e 2019. Trata-se de um estudo ecológico exploratório, descritivo, de natureza documental, com análise de registros hospitalares de câncer em crianças de 0 a  05 anos, atendidos na rede hospitalar de Santa Catarina entre 2009 a 2019. Foram identificados 1.030 registros hospitalares de câncer em crianças com idade ≤ 05 anos no período estudado. A rede assistencial oncológica na primeira infância encontra-se concentrada nas macrorregiões de saúde da Grande Florianópolis e Planalto Norte e Nordeste, sendo estas as regiões mais populosas. Observou-se diminuição das ocorrências nas macrorregiões Grande Florianópolis e Planalto Norte e Nordeste, com importante aumento da macrorregião do Grande Oeste entre 2009 e 2019. Houve uma interiorização dos atendimentos ao longo dos anos, beneficiando regiões que se encontram mais distantes da maioria dos serviços de alta complexidade em oncologia pediátrica.
CARACTERIZAÇÃO DA EPIDEMIA DE HIV/AIDS NO ESCUDO DAS GUIANAS E POSSÍVEL INFLUÊNCIA DAS MIGRAÇÕES NA DISSEMINAÇÃO DO VÍRUS
Authors: Divino Flavia , Peiter Paulo
Published: February 2022

De 1980 a junho de 2020, foram notificados 1.011.617 casos de AIDS no Brasil, (Ministério da Saúde, 2020) e há alguns anos que se verifica uma estabilização na taxa de incidência na América Latina, entretanto são grandes as diferenças regionais no Brasil. As regiões Norte e Nordeste ainda apresentam uma progressão nas taxas de incidência de HIV e não obstante, existe uma variante do HIV-1 do subtipo B, a variante BCAR (B Caribe), que anteriormente era conhecida por sua circulação restrita às ilhas do Caribe e em estudos recentes demonstrou-se sua alta prevalência nos países do Escudo das Guianas. São regiões intimamente ligadas ao Caribe e compartilham em suas fronteiras: culturas, construções sociais, políticas e uma evidente ascensão do HIV e novos casos de AIDS notificados. As mudanças no perfil da AIDS no Brasil vêm mostrando o aumento da transmissão por via heterossexual, uma prevalência de jovens de 15 a 39 anos infectados e uma epidemia que evidencia o desequilíbrio entre as regiões do país. Esses resultados também apontam fortes ligações epidemiológicas entre os países do extremo norte do continente sul-americano, os municípios fronteiriços brasileiros, mobilidade populacional, migração e a epidemia de HIV/AIDS.
Jean-Claude Haelewyck : le parcours d'un chercheur devenu enseignant
Authors: Obsomer Claude
Published: February 2022

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Étude linguistique des mots d’emprunt iraniens en hébreu biblique
Authors: Isebaert Lambert
Published: February 2022

Analyse linguistique de 22 mots iraniens en hébreu biblique.
The Effect of LiBOB Addition on Solid Polymer Electrolyte (SPE) Production based PVDF-HFP/TiO2/LiTFSI on Ionic Conductivity for Lithium-Ion Battery Applications
Authors: Lestariningsih Titik , Sabrina Qolby , Ratri Christin Rina , Subhan Achmad , Priyono Slamet
Published: February 2022

SPE (Solid Polymer Electrolyte) is an alternative to substitute conventional liquid electrolytes as it has a better safety level and has been produced using the solution casting method. An effort to increase the SPE conductivity of the PVDF-HFP/TiO2/ LiTFSI system has been carried out by adding LiBOB as an additive. LiBOB (lithium bis(oxalate) borate) is a salt compound that can interfere with the crystallization process of polymer chains, so it is expected to increase ion conductivity. However, the results showed a decrease in the conductivity from 3.643 x 10-5 S/cm to 8.658 x 10-6 S/cm. These results were proven by the XRD, FTIR, SEM, and TGA characterization. Based on XRD (X-ray Diffraction) analysis, the addition of LiBOB increased the crystallinity phase. The results of the SEM (Scanning Electron Microscope) analysis showed that the pore size was partially reduced, the distance between the pores became longer, and the pore closure occurred due to agglomeration. The FTIR (Fourier Transform Infrared spectroscopy) analysis showed the interaction of LiBOB salts in the PVDF-HFP/LiTFSI/TiO2 system, and based on TGA (Thermogravimetric Analysis) analysis, the addition of LiBOB affected the heat stability of the SPE. The CV (Cyclic Voltammetry) analysis showed that the addition of LiBOB in the SPE system could reduce the reversibility and magnitude of the current.
Negotiating teacher educators' beliefs about blended learning: Using stimulated recall to explore design choices
Authors: Bruggeman Bram , Hidding Kyra , Struyven Katrien , Pynoo Bram , Garone Anja , Tondeur Jo
Published: February 2022

Teachers’ beliefs about education influence practice and vice versa. Teacher educators should be particularly attuned to the association between educational beliefs and practice. Teachers’ beliefs about education have been widely studied, but investigating how a team of teacher educators put a shared vision on blended learning into practice is less researched. Blended learning practices are subject to the four design aspects of incorporating flexibility, stimulating interaction, facilitating the learning process, and creating an affective learning climate. This qualitative study investigates a team of experienced blended learning teacher educators from two perspectives: their beliefs about blended learning, and how these beliefs are realised in practice. Seventeen screencast stimulated recall interviews revealed: (1) teacher educators express evaluative beliefs about deep and meaningful blended learning and descriptive beliefs about online flexibility and face-to-face interaction, and (2) how these beliefs are realised in practice by flexible online facilitation of learning processes, profound face-to-face interaction, and providing authentic learning experiences. Furthermore, as a result of the association between beliefs about blended learning and practice, the areas of refining student feedback, improving online structure and increasing interaction in online learning materials emerged for professional growth. Finally, recommendations are made for blended learning practitioners and teacher educators.
Implications for practice or policy:

Teacher educators hold evaluative beliefs about deep and meaningful blended learning and descriptive beliefs about online flexibility and face-to-face interaction.
Deep and meaningful blended learning is promoted by flexible online facilitation of learning processes, profound face-to-face interaction, and providing authentic learning experiences.
Areas for professional growth are refining student feedback, improving online structure and increasing interaction in online learning materials.
Exploring the concept of the digital educator during COVID-19
Authors: Schalk Ana Elena , McAvinia Claire , Rooney Pauline
Published: February 2022

In this paper, we explore academic identity, specifically the identity of the educator in higher education and academics’ conceptualisations of the digital educator. We suggest that the concept of a digital educator is not only about technology, tools and uses. The context for this exploration is academics’ participation in an online professional development module, Digital Education, and the “pivot online” (Weller, 2020a) during campus closures caused by the COVID-19 pandemic in 2020. Through qualitative research, we explored participants’ sense of teaching identity, whether they had or have a concept of being a digital educator and the extent to which these identities might have shifted while the campus closure continued. We present analysis of their accounts and reflect on the implications of this analysis, particularly in relation to organisational digital capacity defined as “the skills, competencies, attitudes, infrastructure, and resources that enable people to work, live and learn in a world that is increasingly digital world” (National Forum, 2018, p. iv). We consider how higher education institutions will cope with the complex challenges facing us and suggest ways in which the implications of this research could better enable institutions to navigate change and build organisational digital capacity.
Implications for practice or policy:

The pivot to online teaching and assessment during the COVID-19 pandemic has had complex effects on professional identities which need to be researched and understood.
Programme teams in campus-based institutions have experienced erosion of professional norms and relationships. They need support and leadership during the gradual return to campus.
Faculty integrated technologies rapidly but unevenly into practice; therefore, the ongoing building of digital capacity and the shift towards post-digital pedagogies needs dedicated support and leadership.
Effect of omega-3 fatty acids on the telomere length: A mini meta-analysis of clinical trials
Authors: Ali Sawan , Scapagnini Giovanni , Davinelli Sergio
Published: February 2022

Telomeres are protective caps at the end of eukaryotic chromosomes, whose length is correlated with health and lifespan. Telomere attrition is a common feature of the aging process and can be accelerated by oxidative stress and chronic inflammation. Various nutrients influence the telomere length, partially due to their antioxidant and anti-inflammatory properties. The aim of this review was to meta-analytically assess the effect of omega-3 fatty acids on the telomere length. We searched four databases (PubMed, Web of Sciences, Scopus, and the Cochrane Library) from inception until November 2021. Of 573 records, a total of 5 clinical trials were included for the quantitative meta-analysis, comprising a total of 337 participants. The results revealed an overall beneficial effect of omega-3 fatty acids on the telomere length (mean difference = 0.16; 95% CI, 0.02, 0.30; p = 0.02). Despite a limited number of studies, the available evidence suggests that omega-3 fatty acids may positively affect the telomere length. However, larger clinical trials are needed to confirm our findings, along with studies aimed to clarify the underlying molecular mechanisms.