bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplemental Figures S1-S7 from Hepcidin Regulation in Prostate and Its Disruption in Prostate Cancer
Authors: Tesfay Lia , Clausen Kathryn A. , Kim Jin Woo , Hegde Poornima , Wang Xiaohong , Miller Lance D. , Deng Zhiyong , Blanchette Nicole , Arvedson Tara , Miranti Cindy K. , Babitt Jodie L. , Lin Herbert Y. , Peehl Donna M. , Torti Frank M. , Torti Suzy V.
Published: April 2023

Supplemental Figures S1-S7. Hepcidin transcript levels in prostate cells under basal conditions and in response to modulation by signaling effectors (S1); Immunohistochemical detection of hepcidin in prostate tissue (S2); Clonegenic survival of DU145 cells treated with DFO (S3); BMPs induce SMAD signaling in prostate cancer cells (S4); Effect of BMP6 and BMP7 on hepcidin in PC3 and LNCaP prostate cancer cells (S5); Effect of Wnt pathway agonists or antagonists in DU145 cells (S6); Immunohistochemical detection of SOSTDC1 in prostate tissue (S7).
Supplemental Figure Legend from Hepcidin Regulation in Prostate and Its Disruption in Prostate Cancer
Authors: Tesfay Lia , Clausen Kathryn A. , Kim Jin Woo , Hegde Poornima , Wang Xiaohong , Miller Lance D. , Deng Zhiyong , Blanchette Nicole , Arvedson Tara , Miranti Cindy K. , Babitt Jodie L. , Lin Herbert Y. , Peehl Donna M. , Torti Frank M. , Torti Suzy V.
Published: April 2023

Supplemental Figure Legend. Legends to Supplemental Figures S1-S7.
Supplementary Figure S3 from Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b
Authors: Vasilyeva Aksana , Durmus Selvi , Li Lie , Wagenaar Els , Hu Shuiying , Gibson Alice A. , Panetta John C. , Mani Sridhar , Sparreboom Alex , Baker Sharyn D. , Schinkel Alfred H.
Published: April 2023

Plasma and liver concentrations of sorafenib in wildtype, Abcc3(-/-) mice, Oatp1a/1b(-/-), and combination Abcc2(-/-) and Abcc3(-/-) mice.
Supplementary Figure S5 from Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells
Authors: Vilgelm Anna E. , Pawlikowski Jeff S. , Liu Yan , Hawkins Oriana E. , Davis Tyler A. , Smith Jessica , Weller Kevin P. , Horton Linda W. , McClain Colt M. , Ayers Gregory D. , Turner David C. , Essaka David C. , Stewart Clinton F. , Sosman Jeffrey A. , Kelley Mark C. , Ecsedy Jeffrey A. , Johnston Jeffrey N. , Richmond Ann
Published: April 2023

Supplementary Figure S5. (-)-Nutlin-3 treatment affects tumor vasculature in vivo.
Supplementary Figure S1 from Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b
Authors: Vasilyeva Aksana , Durmus Selvi , Li Lie , Wagenaar Els , Hu Shuiying , Gibson Alice A. , Panetta John C. , Mani Sridhar , Sparreboom Alex , Baker Sharyn D. , Schinkel Alfred H.
Published: April 2023

Hepatic uptake and biliary excretion in wildtype and Abcc2(-/-) mice.
Supplementary Figure S4 from Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells
Authors: Vilgelm Anna E. , Pawlikowski Jeff S. , Liu Yan , Hawkins Oriana E. , Davis Tyler A. , Smith Jessica , Weller Kevin P. , Horton Linda W. , McClain Colt M. , Ayers Gregory D. , Turner David C. , Essaka David C. , Stewart Clinton F. , Sosman Jeffrey A. , Kelley Mark C. , Ecsedy Jeffrey A. , Johnston Jeffrey N. , Richmond Ann
Published: April 2023

Supplementary Figure S4. Combined (-)-Nutlin-3 and MLN8237 treatment induces cell death in mouse B16F0 melanoma cells in vitro and in vivo.
Supplementary Figure S2 from Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells
Authors: Vilgelm Anna E. , Pawlikowski Jeff S. , Liu Yan , Hawkins Oriana E. , Davis Tyler A. , Smith Jessica , Weller Kevin P. , Horton Linda W. , McClain Colt M. , Ayers Gregory D. , Turner David C. , Essaka David C. , Stewart Clinton F. , Sosman Jeffrey A. , Kelley Mark C. , Ecsedy Jeffrey A. , Johnston Jeffrey N. , Richmond Ann
Published: April 2023

Supplementary Figure S2. (-)-Nutlin-3 activates p53 in p53WT cells and induces caspase-independent cell death.
Supplementary Table 1 from Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity
Authors: Caruso Hillary G. , Hurton Lenka V. , Najjar Amer , Rushworth David , Ang Sonny , Olivares Simon , Mi Tiejuan , Switzer Kirsten , Singh Harjeet , Huls Helen , Lee Dean A. , Heimberger Amy B. , Champlin Richard E. , Cooper Laurence J.N.
Published: April 2023

Antibodies used in study
Supplementary Figure and Table legends from Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function
Authors: Rajeshkumar N.V. , Dutta Prasanta , Yabuuchi Shinichi , de Wilde Roeland F. , Martinez Gary V. , Le Anne , Kamphorst Jurre J. , Rabinowitz Joshua D. , Jain Sanjay K. , Hidalgo Manuel , Dang Chi V. , Gillies Robert J. , Maitra Anirban
Published: April 2023

Supplementary Figures and Table legends
Supplementary Methods from Leptin–STAT3–G9a Signaling Promotes Obesity-Mediated Breast Cancer Progression
Authors: Chang Chao-Ching , Wu Meng-Ju , Yang Jer-Yen , Camarillo Ignacio G. , Chang Chun-Ju
Published: April 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplementary Figures S1-S5 from Leptin–STAT3–G9a Signaling Promotes Obesity-Mediated Breast Cancer Progression
Authors: Chang Chao-Ching , Wu Meng-Ju , Yang Jer-Yen , Camarillo Ignacio G. , Chang Chun-Ju
Published: April 2023

Supplementary Figures S1-S5. Leptin induces STAT3-G9a interaction and their co-occupancy on targeted gene promoters (S1); Leptin induces EMT and stem cell-like traits via down-regulation of miR-200c (S2); STAT3 and G9a expression is required for OBR induction by leptin (S3); Distinct tumor phenotypes in Western obese animals compared to lean animals (S4); STAT3 activation and OBR overexpression in diet-induced obesity rats (S5).
Supplementary Figure S2: MSMS identification of lipids and polar compounds mentioned in the manuscript from Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids
Authors: Southam Andrew D. , Khanim Farhat L. , Hayden Rachel E. , Constantinou Julia K. , Koczula Katarzyna M. , Michell Robert H. , Viant Mark R. , Drayson Mark T. , Bunce Chris M.
Published: April 2023

MSMS identification of phospholipids and glycerol 3-phosphate using collision induced dissociation (CID) fragmentation.
sup figure legend from Akt Kinase-Interacting Protein 1 Signals through CREB to Drive Diffuse Malignant Mesothelioma
Authors: Yamada Tadaaki , Amann Joseph M. , Fukuda Koji , Takeuchi Shinji , Fujita Naoya , Uehara Hisanori , Iwakiri Shotaro , Itoi Kazumi , Shilo Konstantin , Yano Seiji , Carbone David P.
Published: April 2023

Supplemental Figure legends 1-6
Legends for Supplementary Tables S1 and S2 from Dll4 Blockade in Stromal Cells Mediates Antitumor Effects in Preclinical Models of Ovarian Cancer
Authors: Kuhnert Frank , Chen Guoying , Coetzee Sandra , Thambi Nithya , Hickey Carlos , Shan Jing , Kovalenko Pavel , Noguera-Troise Irene , Smith Eric , Fairhurst Jeanette , Andreev Julian , Kirshner Jessica R. , Papadopoulos Nicholas , Thurston Gavin
Published: April 2023

Legends for Supplementary Tables S1 and S2
Supplementary Figures S1-S4 from YAP Promotes Malignant Progression of Lkb1-Deficient Lung Adenocarcinoma through Downstream Regulation of Survivin
Authors: Zhang Wenjing , Gao Yijun , Li Fuming , Tong Xinyuan , Ren Yan , Han Xiangkun , Yao Shun , Long Fei , Yang Zhongzhou , Fan Hengyu , Zhang Lei , Ji Hongbin
Published: April 2023

The Lungs from SP-C-YAP transgenic mice exhibited higher level of YAP expression in comparison with those of wide type (WT) mice ; Ectopic YAP expression in KrasG12D mice increased lung tumor burden without affecting total tumor number ; The effect of Yap knockout upon tumor number and the percentage of different pathological lesions including AAH/Adenoma, Adenocarcinoma (ADC) and Squamous cell carcinoma ; The functional link between Survivin and Yap in lung tumor growth .
Supplementary figure 3 from Decoy Receptor DcR1 Is Induced in a p50/Bcl3–Dependent Manner and Attenuates the Efficacy of Temozolomide
Authors: Mansour Nassir M. , Bernal Giovanna M. , Wu Longtao , Crawley Clayton D. , Cahill Kirk E. , Voce David J. , Balyasnikova Irina V. , Zhang Wei , Spretz Ruben , Nunez Luis , Larsen Gustavo F. , Weichselbaum Ralph R. , Yamini Bakhtiar
Published: April 2023

Supplementary figure 3. A, annexin V binding in U251 cells treated with vehicle or temozolomide (TMZ, 100 μM) following transfection with the indicated siRNA. B, clonogenic assay in A172 cells transfected with the indicated siRNA following treatment with the indicated concentration of TMZ. C, clonogenic assay in U251 cells transfected with si-RNA and treated with TMZ. *, P < 0.05.
Supplementary figure 2 from Decoy Receptor DcR1 Is Induced in a p50/Bcl3–Dependent Manner and Attenuates the Efficacy of Temozolomide
Authors: Mansour Nassir M. , Bernal Giovanna M. , Wu Longtao , Crawley Clayton D. , Cahill Kirk E. , Voce David J. , Balyasnikova Irina V. , Zhang Wei , Spretz Ruben , Nunez Luis , Larsen Gustavo F. , Weichselbaum Ralph R. , Yamini Bakhtiar
Published: April 2023

Supplementary figure 2. A, ChIP using DCR1 promoter specific primers. Quantitative data show chromatin enrichment of Bcl3 relative to input after controlling for non-specific binding using anti-histone H1 (positive control) and anti-IgG, normalized to vehicle treatment, {plus minus} SD of 3 triplicate samples repeated. Semi-quantitative blot of the PCR product from the p50 and Bcl3 ChIP experiments are shown (right). B, immunoblot with anti-DcR1 or anti-Bcl3 in U87 cells transfected with empty vector (EV) or Bcl3 and treated with 100 μM TMZ for the indicated time. C, qPCR analysis of DCR1 mRNA expression in U87 clones expressing the indicated sh-DcR1 or sh-control construct. Data show mean DCR1 transcript expression relative to GAPDH, {plus minus}SD of triplicate samples. D, trypan blue dye exclusion in sh-cntl and sh-DcR1-3 cells following treatment with vehicle or 100 μM TMZ for the indicated times. Data show mean % cell death, {plus minus} SD of triplicate samples. *, P < 0.05. **, P < 0.01.
Suppl Table S3 from Differentiation and Loss of Malignant Character of Spontaneous Pulmonary Metastases in Patient-Derived Breast Cancer Models
Authors: Bockhorn Jessica , Prat Aleix , Chang Ya-Fang , Liu Xia , Huang Simo , Shang Meng , Nwachukwu Chika , Gomez-Vega Maria J. , Harrell J. Chuck , Olopade Olufunmilayo I. , Perou Charles M. , Liu Huiping
Published: April 2023

Suppl Table S3. miRNAs differentially in the Met-derived models
Supplemental figure and table legends from Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals
Authors: Cedervall Jessica , Zhang Yanyu , Huang Hua , Zhang Lei , Femel Julia , Dimberg Anna , Olsson Anna-Karin
Published: April 2023

Supplemental figure and table legends
Supplementary Figure S1 from JAK Inhibition Impairs NK Cell Function in Myeloproliferative Neoplasms
Authors: Schönberg Kathrin , Rudolph Janna , Vonnahme Maria , Parampalli Yajnanarayana Sowmya , Cornez Isabelle , Hejazi Maryam , Manser Angela R. , Uhrberg Markus , Verbeek Walter , Koschmieder Steffen , Brümmendorf Tim H. , Brossart Peter , Heine Annkristin , Wolf Dominik
Published: April 2023

Supplementary Figure S1. Ruxolitinib does not increase apoptosis rate.
Supplemental Figure 5 from Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals
Authors: Cedervall Jessica , Zhang Yanyu , Huang Hua , Zhang Lei , Femel Julia , Dimberg Anna , Olsson Anna-Karin
Published: April 2023

Supplemental Figure 5: Anti-G-CSF treatment restores kidney vascular function in MMTV-PyMT mice.
Supplemental Figure 3 from Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals
Authors: Cedervall Jessica , Zhang Yanyu , Huang Hua , Zhang Lei , Femel Julia , Dimberg Anna , Olsson Anna-Karin
Published: April 2023

Supplemental Figure 3: DNase treatment restores vascular function in kidneys from RIP1-Tag2 mice.
Supplemental Figure 2 from Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals
Authors: Cedervall Jessica , Zhang Yanyu , Huang Hua , Zhang Lei , Femel Julia , Dimberg Anna , Olsson Anna-Karin
Published: April 2023

Supplemental Figure 2: Neutrophil depletion restores vascular function in kidneys from RIP1-Tag2 mice.
Supplementary Table S1 from Oncogenic Transformation Can Orchestrate Immune Evasion and Inflammation in Human Mesenchymal Stem Cells Independently of Extrinsic Immune-Selective Pressure
Authors: Miranda Alex , Funes Juan M. , Sánchez Nilda , Limia Celia M. , Mesa Mónica , Quezada Sergio A. , Pérez Rolando , de León Joel
Published: April 2023

Supplementary Table S1. Probe Set IDs for microarray's analysis.
Supplementary Figure S1 from A Polymer-Based Antibody–Vinca Drug Conjugate Platform: Characterization and Preclinical Efficacy
Authors: Yurkovetskiy Alexander V. , Yin Mao , Bodyak Natalya , Stevenson Cheri A. , Thomas Joshua D. , Hammond Charles E. , Qin LiuLiang , Zhu Bangmin , Gumerov Dmitry R. , Ter-Ovanesyan Elena , Uttard Alex , Lowinger Timothy B.
Published: April 2023

Synthesis of HPV-Ala-NH2.
Supplemental Table 1 from Evaluating Robustness and Sensitivity of the NanoString Technologies nCounter Platform to Enable Multiplexed Gene Expression Analysis of Clinical Samples
Authors: Veldman-Jones Margaret H. , Brant Roz , Rooney Claire , Geh Catherine , Emery Hollie , Harbron Chris G. , Wappett Mark , Sharpe Alan , Dymond Michael , Barrett J. Carl , Harrington Elizabeth A. , Marshall Gayle
Published: April 2023

Summary of standard deviation calculations based on human Reference RNA sample replicates (R) tested independently on two Prep Stations (S1 and S2). The standard deviation calculations (based on log2 data) are measured as the difference for each gene between each sample replicate (4 replicates on S1 and 3 replicates on S2). The average for each variable is calculated and represented in bold to enable assessment of a trend.
Supplementary Dataset 3 from AKT1 and MYC Induce Distinctive Metabolic Fingerprints in Human Prostate Cancer
Authors: Priolo Carmen , Pyne Saumyadipta , Rose Joshua , Regan Erzsébet Ravasz , Zadra Giorgia , Photopoulos Cornelia , Cacciatore Stefano , Schultz Denise , Scaglia Natalia , McDunn Jonathan , De Marzo Angelo M. , Loda Massimo
Published: April 2023

Metabolomics dataset
Supplementary Methods and Figure Legends from Genetic Disruption of Lactate/H+ Symporters (MCTs) and Their Subunit CD147/BASIGIN Sensitizes Glycolytic Tumor Cells to Phenformin
Authors: Marchiq Ibtissam , Le Floch Renaud , Roux Danièle , Simon Marie-Pierre , Pouyssegur Jacques
Published: April 2023

Supplementary Methods and Figure Legends from Genetic Disruption of Lactate/H+ Symporters (MCTs) and Their Subunit CD147/BASIGIN Sensitizes Glycolytic Tumor Cells to Phenformin
Supplemental Figure Legend from Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer
Authors: Cunha Sara I. , Bocci Matteo , Lövrot John , Eleftheriou Nikolas , Roswall Pernilla , Cordero Eugenia , Lindström Linda , Bartoschek Michael , Haller B. Kristian , Pearsall R. Scott , Mulivor Aaron W. , Kumar Ravindra , Larsson Christer , Bergh Jonas , Pietras Kristian
Published: April 2023

Legends for Supplemental Figures S1-S3.
Supplementary Methods from IL6/JAK1/STAT3 Signaling Blockade in Endometrial Cancer Affects the ALDHhi/CD126+ Stem-like Component and Reduces Tumor Burden
Authors: van der Zee Marten , Sacchetti Andrea , Cansoy Medine , Joosten Rosalie , Teeuwssen Miriam , Heijmans-Antonissen Claudia , Ewing-Graham Patricia C. , Burger Curt W. , Blok Leen J. , Fodde Riccardo
Published: April 2023

Online Supplementary Materials and Methods
Supplementary Movie 6 from STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Efficacious
Authors: Maycotte Paola , Gearheart Christy M. , Barnard Rebecca , Aryal Suraj , Mulcahy Levy Jean M. , Fosmire Susan P. , Hansen Ryan J. , Morgan Michael J. , Porter Christopher C. , Gustafson Daniel L. , Thorburn Andrew
Published: April 2023

MOV file - 2592K, MDAMB468 cells were transduced with an ATG7 shRNA and imaged for 48h.
Supplemental Table S1 from Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas
Authors: He Feng , Melamed Jonathan , Tang Moon-shong , Huang Chuanshu , Wu Xue-Ru
Published: April 2023

Supplemental Table S1. Antibodies used for Western blotting, immunohistochemistry and immunofluorescence.
Supplementary Figures 1 through 7 and Supplementary Tables 1 and 2 from TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor–Binding Sites in Chronic Myelomonocytic Leukemia
Authors: Yamazaki Jumpei , Jelinek Jaroslav , Lu Yue , Cesaroni Matteo , Madzo Jozef , Neumann Frank , He Rong , Taby Rodolphe , Vasanthakumar Aparna , Macrae Trisha , Ostler Kelly R. , Kantarjian Hagop M. , Liang Shoudan , Estecio Marcos R. , Godley Lucy A. , Issa Jean-Pierre J.
Published: April 2023

7 supplementary figures, and 2 supplementary tables. Supplementary Figure 1. Scatter plots for DNA methylation levels analyzed by DREAM. Supplementary Figure 2. Difference in DNA methylation for 7 repeat classes by bisulphite-pyrosequencing for TET2-MT, TET2-WT cases, and normal blood samples. Supplementary Figure 3. Unsupervised hierarchical analyses for DNA methylation levels for all sites analyzed by DREAM. Supplementary Figure 4. Supervised hierarchical analysis for DNA methylation levels for tet2-DMCs. Supplementary Figure 5. Representative genomic landscapes for tet2-DMCs more methylated in TET2-MT in NCGIs. Supplementary Figure 6. Bar plots for the enrichment of tet2-DMCs in NCGI for regulatory including promoter flanking regions, promoters, enhancers, and CTCF binding sites defined by Ensembl Regulatory Build data. Supplementary Figure 7. p300-related genes are deregulated in TET2-MT. Supplementary Table 1. Primer sequences Supplementary Table 2. Number of unique usable tags obtained from DREAM
Supplementary Dataset 2 from WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma
Authors: Sun Yuting , Bell Jessica L. , Carter Daniel , Gherardi Samuele , Poulos Rebecca C. , Milazzo Giorgio , Wong Jason W.H. , Al-Awar Rima , Tee Andrew E. , Liu Pei Y. , Liu Bing , Atmadibrata Bernard , Wong Matthew , Trahair Toby , Zhao Quan , Shohet Jason M. , Haupt Ygal , Schulte Johannes H. , Brown Peter J. , Arrowsmith Cheryl H. , Vedadi Masoud , MacKenzie Karen L. , Hüttelmaier Stefan , Perini Giovanni , Marshall Glenn M. , Braithwaite Antony , Liu Tao
Published: April 2023

List of N-Myc-binding gene promoters at which H3K4me3 was reduced by WDR5 siRNA.
Fig. S8 from Feed-Forward Reciprocal Activation of PAFR and STAT3 Regulates Epithelial–Mesenchymal Transition in Non–Small Cell Lung Cancer
Authors: Chen Jie , Lan Tian , Zhang Weimin , Dong Lijia , Kang Nan , Zhang Shumin , Fu Ming , Liu Bing , Liu Kangtai , Zhan Qimin
Published: April 2023

PAFR expression was associated with E-cadherin, N-cadherin, vimentin, snail, or Zeb-1 expression in 90 primary human NSCLC specimens.
Supplementary Figure 1 from TGFβ Is a Master Regulator of Radiation Therapy-Induced Antitumor Immunity
Authors: Vanpouille-Box Claire , Diamond Julie M. , Pilones Karsten A. , Zavadil Jiri , Babb James S. , Formenti Silvia C. , Barcellos-Hoff Mary Helen , Demaria Sandra
Published: April 2023

Figure 1S: 1D11 treatment inhibits TGFÃŽÂ² pathway signaling in CD4 and CD8 T cells from TDLN.
Supplementary Table S3 from Breast Cancer Cell–Derived GM-CSF Licenses Regulatory Th2 Induction by Plasmacytoid Predendritic Cells in Aggressive Disease Subtypes
Authors: Ghirelli Cristina , Reyal Fabien , Jeanmougin Marine , Zollinger Raphaël , Sirven Philémon , Michea Paula , Caux Christophe , Bendriss-Vermare Nathalie , Donnadieu Marie-Hélène , Caly Martial , Fourchotte Virginie , Vincent-Salomon Anne , Sigal-Zafrani Brigitte , Sastre-Garau Xavier , Soumelis Vassili
Published: April 2023

Supplementary Table S3. Cytokine measurements in primary breast tumor (Tum) and juxtatumor (Juxta) supernatants.
Supplementary Figure S2 from IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism
Authors: Izquierdo-Garcia Jose L. , Viswanath Pavithra , Eriksson Pia , Cai Larry , Radoul Marina , Chaumeil Myriam M. , Blough Michael , Luchman H. Artee , Weiss Samuel , Cairncross J. Gregory , Phillips Joanna J. , Pieper Russell O. , Ronen Sabrina M.
Published: April 2023

Cytotoxicity of DCA against IDH1 wild-type and mutant cells for the U87 (A) and NHA (B) models (* indicates significant difference (p<0.05) relative to control).
Supplemental Figure S6 from Tumor Endothelial Cells with Distinct Patterns of TGFβ-Driven Endothelial-to-Mesenchymal Transition
Authors: Xiao Lin , Kim Dae Joong , Davis Clayton L. , McCann James V. , Dunleavey James M. , Vanderlinden Alissa K. , Xu Nuo , Pattenden Samantha G. , Frye Stephen V. , Xu Xia , Onaitis Mark , Monaghan-Benson Elizabeth , Burridge Keith , Dudley Andrew C.
Published: April 2023

Supplemental Figure S6. bFGF suppresses TGFβ2-induced mesenchymal gene expression in K-Ras lung TEC clones.
Table S1 from A Sucrose-Enriched Diet Promotes Tumorigenesis in Mammary Gland in Part through the 12-Lipoxygenase Pathway
Authors: Jiang Yan , Pan Yong , Rhea Patrea R. , Tan Lin , Gagea Mihai , Cohen Lorenzo , Fischer Susan M. , Yang Peiying
Published: April 2023

Diet formulation.
Supplemental Methods and References from SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex
Authors: Feng Yongmei , Pinkerton Anthony B. , Hulea Laura , Zhang Tongwu , Davies Michael A. , Grotegut Stefan , Cheli Yann , Yin Hongwei , Lau Eric , Kim Hyungsoo , De Surya K. , Barile Elisa , Pellecchia Maurizio , Bosenberg Marcus , Li Jian-Liang , James Brian , Hassig Christian A. , Brown Kevin M. , Topisirovic Ivan , Ronai Ze'ev A.
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplemental References.
Supplemental Figure S1 from SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex
Authors: Feng Yongmei , Pinkerton Anthony B. , Hulea Laura , Zhang Tongwu , Davies Michael A. , Grotegut Stefan , Cheli Yann , Yin Hongwei , Lau Eric , Kim Hyungsoo , De Surya K. , Barile Elisa , Pellecchia Maurizio , Bosenberg Marcus , Li Jian-Liang , James Brian , Hassig Christian A. , Brown Kevin M. , Topisirovic Ivan , Ronai Ze'ev A.
Published: April 2023

In vivo PK and non-toxic effect of SBI-756.
Supplementary Figures S1-S9 from Fluorophore-NanoLuc BRET Reporters Enable Sensitive In Vivo Optical Imaging and Flow Cytometry for Monitoring Tumorigenesis
Authors: Schaub Franz X. , Reza Md. Shamim , Flaveny Colin A. , Li Weimin , Musicant Adele M. , Hoxha Sany , Guo Min , Cleveland John L. , Amelio Antonio L.
Published: April 2023

Supplementary Figures S1-S9. Figure S1. Functional evaluation of the GpNLuc LumiFluor. Figure S2. In vitro characterization of FACS sorted mouse Em-Myc lymphoma and human non-small cell lung cancer (NSCLC) cells. Figure S3. Temporal development of A549 NSCLC xenograft tumors expressing GpNLuc or GpNLuc and the tumor suppressor LKB1. Figure S4. Detection of spontaneous lymph node metastasis from primary lung tumors. Figure S5. In vitro and in vivo characterization of independently derived E?-Myc lymphoma cells stably expressing GpNLuc. Figure S6. Bioluminescence imaging of E?-Myc lymphoma-GpNLuc allografts. Figure S7. A, in vivo dose-response kinetics of GpNLuc signal strength. Figure S8. Quantification of in vivo bioluminescence imaging and confirmation ex vivo. Figure S9. Flow cytometric analysis of inducibly expressed fluorescent proteins in stable lymphoma cell lines.
supplemental figure legends from Combining miR-10b–Targeted Nanotherapy with Low-Dose Doxorubicin Elicits Durable Regressions of Metastatic Breast Cancer
Authors: Yoo Byunghee , Kavishwar Amol , Ross Alana , Wang Ping , Tabassum Doris P. , Polyak Kornelia , Barteneva Natalia , Petkova Victoria , Pantazopoulos Pamela , Tena Aseda , Moore Anna , Medarova Zdravka
Published: April 2023

supplemental figure legends
Supplemental Table S8- from The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma
Authors: Harms Paul William , Vats Pankaj , Verhaegen Monique Elise , Robinson Dan R. , Wu Yi-Mi , Dhanasekaran Saravana Mohan , Palanisamy Nallasivam , Siddiqui Javed , Cao Xuhong , Su Fengyun , Wang Rui , Xiao Hong , Kunju Lakshmi P. , Mehra Rohit , Tomlins Scott A. , Fullen Douglas Randall , Bichakjian Christopher Keram , Johnson Timothy M. , Dlugosz Andrzej Antoni , Chinnaiyan Arul M.
Published: April 2023

Supplemental Table S8. Insertions/deletions in MCC tumors
Supplemental Table S6 from The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma
Authors: Harms Paul William , Vats Pankaj , Verhaegen Monique Elise , Robinson Dan R. , Wu Yi-Mi , Dhanasekaran Saravana Mohan , Palanisamy Nallasivam , Siddiqui Javed , Cao Xuhong , Su Fengyun , Wang Rui , Xiao Hong , Kunju Lakshmi P. , Mehra Rohit , Tomlins Scott A. , Fullen Douglas Randall , Bichakjian Christopher Keram , Johnson Timothy M. , Dlugosz Andrzej Antoni , Chinnaiyan Arul M.
Published: April 2023

Supplemental Table S6. Nonsynonymous somatic mutations in MCC tumors
Supplementary Fig. S4 from Combining miR-10b–Targeted Nanotherapy with Low-Dose Doxorubicin Elicits Durable Regressions of Metastatic Breast Cancer
Authors: Yoo Byunghee , Kavishwar Amol , Ross Alana , Wang Ping , Tabassum Doris P. , Polyak Kornelia , Barteneva Natalia , Petkova Victoria , Pantazopoulos Pamela , Tena Aseda , Moore Anna , Medarova Zdravka
Published: April 2023

Supplementary Fig. S4. miR-10b expression in primary tumors vs. lymph node metastases of mice implanted orthotopically with MDA-MB-231-luc-D3H2LN cells.
Supplemental Figure S4 from The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma
Authors: Harms Paul William , Vats Pankaj , Verhaegen Monique Elise , Robinson Dan R. , Wu Yi-Mi , Dhanasekaran Saravana Mohan , Palanisamy Nallasivam , Siddiqui Javed , Cao Xuhong , Su Fengyun , Wang Rui , Xiao Hong , Kunju Lakshmi P. , Mehra Rohit , Tomlins Scott A. , Fullen Douglas Randall , Bichakjian Christopher Keram , Johnson Timothy M. , Dlugosz Andrzej Antoni , Chinnaiyan Arul M.
Published: April 2023

Supplemental Figure S4. A novel MLH1-SPATA4 gene fusion
Supplementary Fig. S1 from Combining miR-10b–Targeted Nanotherapy with Low-Dose Doxorubicin Elicits Durable Regressions of Metastatic Breast Cancer
Authors: Yoo Byunghee , Kavishwar Amol , Ross Alana , Wang Ping , Tabassum Doris P. , Polyak Kornelia , Barteneva Natalia , Petkova Victoria , Pantazopoulos Pamela , Tena Aseda , Moore Anna , Medarova Zdravka
Published: April 2023

Supplementary Fig. S1. Viability of 4T1, SUM149PT and SUM159PT breast cancer cells treated with MN-anti-miR10b and low-dose doxorubicin.
Supplemental Figure S3 from A Urokinase Receptor–Bim Signaling Axis Emerges during EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma
Authors: Wykosky Jill , Hu Jingjing , Gomez German G. , Taylor Tiffany , Villa Genaro R. , Pizzo Donald , VandenBerg Scott R. , Thorne Amy Haseley , Chen Clark C. , Mischel Paul S. , Gonias Steven L. , Cavenee Webster K. , Furnari Frank B.
Published: April 2023

Supplemental Figure S3. Suppression of Akt activation in resistant clones
Supplemental Figure S2 from A Urokinase Receptor–Bim Signaling Axis Emerges during EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma
Authors: Wykosky Jill , Hu Jingjing , Gomez German G. , Taylor Tiffany , Villa Genaro R. , Pizzo Donald , VandenBerg Scott R. , Thorne Amy Haseley , Chen Clark C. , Mischel Paul S. , Gonias Steven L. , Cavenee Webster K. , Furnari Frank B.
Published: April 2023

Supplemental Figure S2. Viability assay of resistant cell lines
Supplementary Figure S9 from PIK3CAH1047R Accelerates and Enhances KRASG12D-Driven Lung Tumorigenesis
Authors: Green Shon , Trejo Christy L. , McMahon Martin
Published: April 2023

Inhibitory effects of BYL719 on tumorigenesis and signaling in human KRASQ61H/PIK3CAE545K-driven H460 lung cancer cells.
Supplementary Figure S8 from PIK3CAH1047R Accelerates and Enhances KRASG12D-Driven Lung Tumorigenesis
Authors: Green Shon , Trejo Christy L. , McMahon Martin
Published: April 2023

Inhibitory effects of pathway-targeted agents on the proliferation of lung tumor derived cell lines of defined Kras or Pik3ca genotype.
Figure S1 from Interleukin-5 Facilitates Lung Metastasis by Modulating the Immune Microenvironment
Authors: Zaynagetdinov Rinat , Sherrill Taylor P. , Gleaves Linda A. , McLoed Allyson G. , Saxon Jamie A. , Habermann Arun C. , Connelly Linda , Dulek Daniel , Peebles R. Stokes , Fingleton Barbara , Yull Fiona E. , Stathopoulos Georgios T. , Blackwell Timothy S.
Published: April 2023

Figure S1. Lung eosinophils (Eos), identified as CD45+/CD11c-/ F4/80+/siglec-F+ cells using flow cytometry are A) negative for CD68, B) express high levels of CCR3, and C) express low levels of Gr1 compared to the CD45+/Gr1hi neutrophils (PMN).
Supplementary Figure 6 from IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras–Mutant Lung Cancer
Authors: Caetano Mauricio S. , Zhang Huiyuan , Cumpian Amber M. , Gong Lei , Unver Nese , Ostrin Edwin J. , Daliri Soudabeh , Chang Seon Hee , Ochoa Cesar E. , Hanash Samir , Behrens Carmen , Wistuba Ignacio I. , Sternberg Cinthya , Kadara Humam , Ferreira Carlos Gil , Watowich Stephanie S. , Moghaddam Seyed Javad
Published: April 2023

Supplementary Figure 6. Increased levels of IL-6 in bronchoalveolar lavage fluid (BALF) of CC-LR mice after NTHi exposure.
Supplementary Figure 5 from IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras–Mutant Lung Cancer
Authors: Caetano Mauricio S. , Zhang Huiyuan , Cumpian Amber M. , Gong Lei , Unver Nese , Ostrin Edwin J. , Daliri Soudabeh , Chang Seon Hee , Ochoa Cesar E. , Hanash Samir , Behrens Carmen , Wistuba Ignacio I. , Sternberg Cinthya , Kadara Humam , Ferreira Carlos Gil , Watowich Stephanie S. , Moghaddam Seyed Javad
Published: April 2023

Supplementary Figure 5. Relative expression of Arg1 mRNA normalized by Cd45 expression in lungs of CC-LR mice.
Supplementary Figure Legends from PIK3CAH1047R Accelerates and Enhances KRASG12D-Driven Lung Tumorigenesis
Authors: Green Shon , Trejo Christy L. , McMahon Martin
Published: April 2023

Legends for Supplementary Figures S1-S9.
Supplementary Table 2 from Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis
Authors: Sorokin Alexey V. , Nair Binoj C. , Wei Yongkun , Aziz Kathryn E. , Evdokimova Valentina , Hung Mien-Chie , Chen Junjie
Published: April 2023

Immunohistochemical expression of proPTPRN2 in invasive breast carcinoma specimens in National Cancer Institute Progression tumor microarrays.
Supplementary Figure S3 from Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations
Authors: Emir Uzay E. , Larkin Sarah J. , de Pennington Nick , Voets Natalie , Plaha Puneet , Stacey Richard , Al-Qahtani Khalid , Mccullagh James , Schofield Christopher J. , Clare Stuart , Jezzard Peter , Cadoux-Hudson Tom , Ansorge Olaf
Published: April 2023

2-hydroxyglutarate (2-HG), Glycine (Gly) and Lactate (Lac) detection by semi-LASER at 7T.
Supplemental Figure S2 from Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network
Authors: Zhu Jieqing , Xiong Gaofeng , Fu Hanjiang , Evers B. Mark , Zhou Binhua P. , Xu Ren
Published: April 2023

Supplemental Figure S2. MiR-29 is a potential regulator of multiple ECM network genes.
Table S2. Gene Set Enrichment Analysis (GSEA) C5 GO gene sets. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma
Authors: Ravi Dashnamoorthy , Beheshti Afshin , Abermil Nasséra , Passero Frank , Sharma Jaya , Coyle Michael , Kritharis Athena , Kandela Irawati , Hlatky Lynn , Sitkovsky Michail V. , Mazar Andrew , Gartenhaus Ronald B. , Evens Andrew M.
Published: April 2023

Complete list of GSEA for C5 GO gene sets in the ixazomib 25nM/24 hours vs. Control for Jurkat, L428, and L540 cells. Leading edge analysis with a FDR {less than or equal to} 0.05 determined significant gene sets enriched for each group. The normalized enrichment score (NES) indicates whether the gene set is up- (>0) or down-regulated (<0) for each group determined with the # of leading edge genes (appears in parenthesis).
Supplementary Legends from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma
Authors: Ravi Dashnamoorthy , Beheshti Afshin , Abermil Nasséra , Passero Frank , Sharma Jaya , Coyle Michael , Kritharis Athena , Kandela Irawati , Hlatky Lynn , Sitkovsky Michail V. , Mazar Andrew , Gartenhaus Ronald B. , Evens Andrew M.
Published: April 2023

Legends for Figure S1, S2 and S3
Supplemental Video 2 from A Quantitative System for Studying Metastasis Using Transparent Zebrafish
Authors: Heilmann Silja , Ratnakumar Kajan , Langdon Erin M. , Kansler Emily R. , Kim Isabella S. , Campbell Nathaniel R. , Perry Elizabeth B. , McMahon Amy J. , Kaufman Charles K. , van Rooijen Ellen , Lee William , Iacobuzio-Donahue Christine A. , Hynes Richard O. , Zon Leonard I. , Xavier Joao B. , White Richard M.
Published: April 2023

Supplemental Video 2: Time-lapse video from 1-21 days post transplantation of ZMEL1-GFP cells into adult zebrafish showing primary growth and metastatic spread.
Supplemental Video 1 from A Quantitative System for Studying Metastasis Using Transparent Zebrafish
Authors: Heilmann Silja , Ratnakumar Kajan , Langdon Erin M. , Kansler Emily R. , Kim Isabella S. , Campbell Nathaniel R. , Perry Elizabeth B. , McMahon Amy J. , Kaufman Charles K. , van Rooijen Ellen , Lee William , Iacobuzio-Donahue Christine A. , Hynes Richard O. , Zon Leonard I. , Xavier Joao B. , White Richard M.
Published: April 2023

Supplemental Video 1: 12 hours post-transplantation of ZMEL1-GFP cells into larval zebrafish showing cells in widespread circulation
Supplemental Table 2 from A Quantitative System for Studying Metastasis Using Transparent Zebrafish
Authors: Heilmann Silja , Ratnakumar Kajan , Langdon Erin M. , Kansler Emily R. , Kim Isabella S. , Campbell Nathaniel R. , Perry Elizabeth B. , McMahon Amy J. , Kaufman Charles K. , van Rooijen Ellen , Lee William , Iacobuzio-Donahue Christine A. , Hynes Richard O. , Zon Leonard I. , Xavier Joao B. , White Richard M.
Published: April 2023

Supplemental Table 2. This data provides transcriptomic analysis of the ZMEL1 line (RNA-seq) along with GSEA analysis comparing ZMEL1 to either human melanomas or primary zebrafish transgenic melanomas.
Supplemental Methods from A Quantitative System for Studying Metastasis Using Transparent Zebrafish
Authors: Heilmann Silja , Ratnakumar Kajan , Langdon Erin M. , Kansler Emily R. , Kim Isabella S. , Campbell Nathaniel R. , Perry Elizabeth B. , McMahon Amy J. , Kaufman Charles K. , van Rooijen Ellen , Lee William , Iacobuzio-Donahue Christine A. , Hynes Richard O. , Zon Leonard I. , Xavier Joao B. , White Richard M.
Published: April 2023

This file provides additional information on reagents and software analysis of images.
Supplementary Table S1 from Radiation Sensitivity in a Preclinical Mouse Model of Medulloblastoma Relies on the Function of the Intrinsic Apoptotic Pathway
Authors: Crowther Andrew J. , Ocasio Jennifer K. , Fang Fang , Meidinger Jessica , Wu Jaclyn , Deal Allison M. , Chang Sha X. , Yuan Hong , Schmid Ralf , Davis Ian , Gershon Timothy R.
Published: April 2023

List of published p53 targets used for transcriptomic analysis.
Supplementary Figure S2 from Identification of Patients with Recurrent Glioblastoma Who May Benefit from Combined Bevacizumab and CCNU Therapy: A Report from the BELOB Trial
Authors: Erdem-Eraslan Lale , van den Bent Martin J. , Hoogstrate Youri , Naz-Khan Hina , Stubbs Andrew , van der Spek Peter , Böttcher René , Gao Ya , de Wit Maurice , Taal Walter , Oosterkamp Hendrika M. , Walenkamp Annemiek , Beerepoot Laurens V. , Hanse Monique C.J. , Buter Jan , Honkoop Aafke H. , van der Holt Bronno , Vernhout René M. , Smitt Peter A.E. Sillevis , Kros Johan M. , French Pim J.
Published: April 2023

Performance of DASL and RNA-seq on RNA isolated from FFPE tissues, correlation with snap frozen samples.
Supplemental Figure S2 from MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell–Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages
Authors: Yamada Kazuya , Uchiyama Akihiko , Uehara Akihito , Perera Buddhini , Ogino Sachiko , Yokoyama Yoko , Takeuchi Yuko , Udey Mark C. , Ishikawa Osamu , Motegi Sei-ichiro
Published: April 2023

This file contains two supplementary figure S2. from Supplemental Figure S2: A. The amount of CD68+ macrophages in melanoma tumor in mice treated with clodronate liposomes or control liposomes. B. Survival in mice implanted with melanoma cells and MFG-E8 WT/KO MSC treated with clodoronate liposomes or control liposomes.
Supplemental Figure S1 from MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell–Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages
Authors: Yamada Kazuya , Uchiyama Akihiko , Uehara Akihito , Perera Buddhini , Ogino Sachiko , Yokoyama Yoko , Takeuchi Yuko , Udey Mark C. , Ishikawa Osamu , Motegi Sei-ichiro
Published: April 2023

This file contains supplementary figure S1. Supplemental Figure S1: Proliferation and mRNA levels of MFG-E8 in MSC derived from BM in WT mice cultured under normoxia or hypoxia condition for 48 hours.
supplemental Figure 2 from BAFF and APRIL from Activin A–Treated Dendritic Cells Upregulate the Antitumor Efficacy of Dendritic Cells In Vivo
Authors: Shurin Michael R. , Ma Yang , Keskinov Anton A. , Zhao Ruijing , Lokshin Anna , Agassandian Marianna , Shurin Galina V.
Published: April 2023

Activin A does not alter phenotypic maturation of DC.
supplemental Figure 1 from BAFF and APRIL from Activin A–Treated Dendritic Cells Upregulate the Antitumor Efficacy of Dendritic Cells In Vivo
Authors: Shurin Michael R. , Ma Yang , Keskinov Anton A. , Zhao Ruijing , Lokshin Anna , Agassandian Marianna , Shurin Galina V.
Published: April 2023

Activin A does not change the expression of CD25 on CD8 and CD4 T-cells in vitro.
Supplemental Table SI from BAFF and APRIL from Activin A–Treated Dendritic Cells Upregulate the Antitumor Efficacy of Dendritic Cells In Vivo
Authors: Shurin Michael R. , Ma Yang , Keskinov Anton A. , Zhao Ruijing , Lokshin Anna , Agassandian Marianna , Shurin Galina V.
Published: April 2023

Activin A treatment does not alter expression of common cytokines in DC
Table S5 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: April 2023

Clinocopathological parameters of breast cancers used for ChIP-seq
Table S4 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: April 2023

Accession numbers of Ishikawa RNA-seq and ChIP-seq datasets generated by the ENCODE consortium and publicly available ERalpha ChIP-seq data from breast tumors.
Supplemental Figure 2 from SOX4 Is Essential for Prostate Tumorigenesis Initiated by PTEN Ablation
Authors: Bilir Birdal , Osunkoya Adeboye O. , Wiles W. Guy , Sannigrahi Soma , Lefebvre Veronique , Metzger Daniel , Spyropoulos Demetri D. , Martin W. David , Moreno Carlos S.
Published: April 2023

Supplemental Figure 2 Figure S2. Probasin-Cre mice (3) obtained from the NCI mouse repository were crossed to ROSA-lox-stop-lox-GFP mice (C57/BL6;129-ROSA26-Lox-Stop-Lox-EGFP (Charles River Laboratories)). Tissues were harvested from male mice after reaching sexual maturity at 8 weeks of age. GFP imaging of organs was performed on an Olympus OV-100 In Vivo Imaging System. Representative tissues from double transgenic mice are shown on the left, and from control mice on the right. Strong GFP signal was detected in pancreas and all three lobes of the prostate.
Supplemental Figure 1 from SOX4 Is Essential for Prostate Tumorigenesis Initiated by PTEN Ablation
Authors: Bilir Birdal , Osunkoya Adeboye O. , Wiles W. Guy , Sannigrahi Soma , Lefebvre Veronique , Metzger Daniel , Spyropoulos Demetri D. , Martin W. David , Moreno Carlos S.
Published: April 2023

Supplemental Figure 1 Figure S1. Breeding scheme for generation of prostate epithelium-specific Sox4 and Pten conditional double-knockout mice. Male PSA-CRE-ER/PTENfl/fl mice (1) were crossed with female Sox4fl/fl mice (2) and bred to homozygosity.
Figure S7 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: April 2023

Scatter plot showing the relationship between ERalpha (X-axis) and FOXA1 (Y-axis) staining
Figure S6 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: April 2023

2D graph, showing normalized read count of the shared binding sites for ERalpha and FOXA1 (blue), ERalpha only (red) and FOXA1 only (green) in ChIP-seq datasets of all indicated transcriptional regulators in the endometrial cancer cell line Ishikawa (ENCODE, see Supplementary table S4).
Supplementary Figure 5 from Activation of Hematopoietic Stem/Progenitor Cells Promotes Immunosuppression Within the Pre–metastatic Niche
Authors: Giles Amber Jin , Reid Caitlin Marie , Evans Justin DeWayne , Murgai Meera , Vicioso Yorleny , Highfill Steven Lorenz , Kasai Miki , Vahdat Linda , Mackall Crystal Lee , Lyden David , Wexler Leonard , Kaplan Rosandra Natasha
Published: April 2023

Myeloid subsets in pre/early metastatic lung
Figure S5 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: April 2023

RT-PCR analysis of 20 transcription factors in four tamoxifen-associated endometrial tumors and Ishikawa cells. Corresponding primers can be found in supplementary table S6.
Supplementary Figure 2 from Activation of Hematopoietic Stem/Progenitor Cells Promotes Immunosuppression Within the Pre–metastatic Niche
Authors: Giles Amber Jin , Reid Caitlin Marie , Evans Justin DeWayne , Murgai Meera , Vicioso Yorleny , Highfill Steven Lorenz , Kasai Miki , Vahdat Linda , Mackall Crystal Lee , Lyden David , Wexler Leonard , Kaplan Rosandra Natasha
Published: April 2023

Analysis of the bone marrow microenvironment and CXCR4 expression on E0771 BCA Tumor cells
Figure S1 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: April 2023

Validation of two FOXA1 antibodies that were used for either ChIP or immunohistochemistry.
Supplementary Table S6 from miR-146b-5p within BCR-ABL1–Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
Authors: Zhang Hong-Mei , Li Qing , Zhu Xiaojian , Liu Wei , Hu Hui , Liu Teng , Cheng Fanjun , You Yong , Zhong Zhaodong , Zou Ping , Li Qiubai , Chen Zhichao , Guo An-Yuan
Published: April 2023

Supplementary Table S6. TF and miRNA co-regulatory network for the Cell cycle and DNA repair pathways.
Supplementary Table S2 from miR-146b-5p within BCR-ABL1–Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
Authors: Zhang Hong-Mei , Li Qing , Zhu Xiaojian , Liu Wei , Hu Hui , Liu Teng , Cheng Fanjun , You Yong , Zhong Zhaodong , Zou Ping , Li Qiubai , Chen Zhichao , Guo An-Yuan
Published: April 2023

Supplementary Table S2. Summary of gene and miRNA expression by different expression level
Supplementary Table S1,4 and Figures from miR-146b-5p within BCR-ABL1–Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
Authors: Zhang Hong-Mei , Li Qing , Zhu Xiaojian , Liu Wei , Hu Hui , Liu Teng , Cheng Fanjun , You Yong , Zhong Zhaodong , Zou Ping , Li Qiubai , Chen Zhichao , Guo An-Yuan
Published: April 2023

Supplementary Tables 1,4 and Figures.docx Supplementary Table S1: Summary of RNA-seq and smRNA-seq data Supplementary Table S4: The information of cancer related pathways Supplementary Figure S1: Project design and flowchart of the study Supplementary Figure S2: Cluster of differentially expressed genes Supplementary Figure S3: Heatmap of the expression of key TFs and miRNAs in the transformation Supplementary Figure S4: Regulatory network for K562-MVs highly expressed TFs and miRNAs Supplementary Figure S5: Expression of miR-146b-5p in K562-MVs after infection Supplementary Figure S6: Level of NUMB mRNA in the recipient cells when NUMB-lentivirus was transfected
Supplementary Figure Legends from TMEM2 Is a SOX4-Regulated Gene That Mediates Metastatic Migration and Invasion in Breast Cancer
Authors: Lee Hyeseung , Goodarzi Hani , Tavazoie Sohail F. , Alarcón Claudio R.
Published: April 2023

This file contains supplementary figure legends only.
Supplementary table from CK2α' Drives Lung Cancer Metastasis by Targeting BRMS1 Nuclear Export and Degradation
Authors: Liu Yuan , Amin Elianna B. , Mayo Marty W. , Chudgar Neel P. , Bucciarelli Peter R. , Kadota Kyuichi , Adusumilli Prasad S. , Jones David R.
Published: April 2023

Patient Demographics for TMA.