bluuebunny/crossref_metadata_2025 huggingface dataset:
Singularidades poéticas da hiperconexão: usos de links eletrônicos em poemas de Marie Bélisle
Authors: Pereira Vinícius
Published: June 2020

Não obstante sua relevância na história das concepções de texto e das tecnologias digitais, a noção de hipertexto frequentemente se esvazia na academia, seja pela inflação semântica a que é submetido para designar dinâmicas de linguagem muito distintas, seja pelo fato de que praticamente todos os discursos na Internet se organizam de modo hipertextual/hipermidiático. Mais especificamente no que tange à literatura eletrônica – campo artístico em franca expansão –, as pesquisas precisam ir além da constatação da organização hipertextual das obras digitais; nesse sentido, devem buscar entender as singulares operações poéticas que o hipertexto pode ensejar e seus respectivos efeitos de sentido. Nessa direção, o presente artigo propõe uma leitura de hiperpoemas de Alter ego, Figures e Lames, desenvolvidos em Flash pela artista québecquense Marie Bélisle. Nessa análise, enfocaremos as operações poéticas engendradas pelo recurso de hiperlinks, para tanto propondo uma categorização de poéticas hipertextuais de alternância, expansão e redistribuição.
A atualização da experiência humana: o poema em questão
Authors: Neumann Daiane , Garcia dos Anjos Aroldo
Published: June 2020

O presente trabalho tem por objetivo discutir a noção de enunciação, de Émile Benveniste, como atualização da experiência humana. Para tanto, serão discutidas as noções de experiência e de linguagem, a partir de escritos de Giorgio Agamben, Walter Benjamin e Émile Benveniste. Em um primeiro momento, será considerada a leitura de Agamben das obras de Benjamin e de Benveniste, na qual o autor propõe a experiência da linguagem como origem da história. Posteriormente, será observado como Benveniste constrói sua concepção de linguagem como fundante da experiência, para, por fim, pensar sobre a linguagem e o poema, considerando as reflexões de Henri Meschonnic.
A Multilevel Research on the Factors Influencing Employee Loyalty Under the New Employer Economics
Authors: Zhong Xin , Zhang You Xin , Li Sheng , Liu Yue
Published: June 2020

Existing research shows that scholars try to achieve the goal of employee loyalty through human resource management practices at the organization level. However, the new employer economics proposes a tendency from “employer-centered” to “employee-centered”. Through a multi-level research method, this paper used 40 teams and found that employer brands had a significantly positive effect on employee loyalty. Basic psychological needs played a mediating role between employer brand and employee loyalty, but the team identification didn’t mediate the relationship between employer brand and employee loyalty. At last, the moderating role of servant leadership between employer brand and employee loyalty was not proved.
Modelo semipresencial para la formación universitaria. Aplicación a titulaciones técnicas
Authors: Fernández Oliveras Paz , Rodríguez Ponce María del Carmen , Fernández-Oliveras Alicia
Published: June 2020

Elaboramos un modelo didáctico innovador para el aprendizaje autónomo en la universidad en modalidad semipresencial, que incluye estructura, características didácticas de sus elementos y evaluación. Ejemplificado mediante un tema de matemáticas e implementado a través de Moodle, el modelo se aplicó en titulaciones técnicas universitarias y se realizó un control del logro de contenidos y competencias, obteniéndose una superación promedio del 70 % entre ambos aspectos evaluados. Según la validación realizada mediante consulta a expertos, el modelo es adecuado para sus objetivos. Mediante una encuesta de valoración del modelo, el alumnado participante manifestó una gran satisfacción con todos los recursos utilizados. El modelo promueve la independencia cognoscitiva y el trabajo autónomo del estudiantado, modificando el rol del profesorado, acorde con una universidad con proyección de futuro.
Integralidade nos processos de dispensação de cadeiras de rodas: estudo de caso de um centro de referência em reabilitação
Authors: Mei Andre Eduardo , Gasparetto Maria Elisabete Rodrigues Freire , Ferretti Eliana Chaves , Nakamura Helenice Yemi
Published: June 2020

A integralidade, um dos princípios do Sistema Único de Saúde, é visto como conceito complexo e polissêmico, de forma a ser associado a três grandes conjuntos de sentidos, entre eles, o conjunto relativo à integração e organização de diferentes serviços de modo a contribuir para a continuidade do cuidado. Este estudo teve por objetivo contribuir para a discussão da integralidade nos processos de dispensação de cadeiras de rodas a partir da experiência de um Centro de Referência em Reabilitação situado no interior do Estado de São Paulo. Realizou-se pesquisa qualitativa, por meio de estudo de caso holístico cuja unidade de análise foi a dispensação de cadeiras de rodas. Os dados foram coletados por meio da construção de fluxograma descritor e analisador, do grupo focal com as profissionais e da observação assistemática. A dispensação de cadeiras de rodas se mostrou como uma construção norteada pela integralidade, superando o modelo assistencialista e se consolidando como conduta técnica. Nesse contexto, assumiu alta responsabilidade, dado o grande volume de unidades dispensadas, e se fundamentou nas etapas de inscrição, montagem, entrega e orientações. Como ponto fraco, as profissionais perceberam lacunas nas ofertas assistenciais e no sistema logístico, e como ponto forte, a apropriação do processo licitatório. Destacou-se a dimensão da integralidade relativa à organização de serviços e práticas, sendo que existe necessidade de maior integração da dispensação com outros pontos de cuidado e da rede.
Um levantamento sobre o uso de algoritmos de aprendizado de máquina em auditorias de planos de saúde
Authors: Fernandes Anita Maria da Rocha , Raduenz Jean Carlo
Published: June 2020

Apesar das operadoras de saúde terem mais de 47 milhões de clientes com plano de saúde no Brasil, estas companhias ainda possuem processos que são manuais. Um destes processos é o de auditoria médica que realiza a análise de cada conta com despesas que foram realizadas pelo beneficiário da operadora em algum hospital, clínica ou laboratório. Cada conta é analisada com o objetivo de verificar se não existe algo fora do contexto de uma cirurgia, exame ou consulta. Os custos destas auditorias são elevados e o resultado é variado e de acordo com o conhecimento individual do auditor. Além de ser um processo demorado, estas contas somente serão pagas para quem prestou o serviço após a análise dos auditores, trazendo insatisfação para quem aguarda o pagamento. A execução manual deste processo está suscetível a falhas e fraudes. Neste contexto, os algoritmos de Aprendizado de Máquina são utilizados para auxiliar no processo de auditoria em várias áreas do conhecimento. Sendo assim, este artigo .
Exploring the impact of Crohn’s disease on the intragastric environment of fasted adults
Authors: Vertzoni Maria , Koulouri Christina , Poulou Androniki , Goumas Konstantinos , Reppas Christos
Published: June 2020

We explored the potential impact of Crohn’s disease on the intragastric environment of fasted adults with a view to potential effects on intragastric performance of orally administered drugs in the fasted state. Data were collected from 15 healthy individuals and 15 patients with Crohn’s disease. All subjects remained fasted for at least 12h prior to gastroscopy. Intragastric resting volume and pH were measured upon aspiration. Osmolality, surface tension, pepsin activity, and content of six bile acids were measured within 4 months upon sample collection. Unlike intragastric volumes, intragastric osmolality was significantly increased by Crohn’s disease. However, mean osmolality value in patients was only slightly higher than in healthy individuals (293 vs. 257 mOsmol/kg, respectively), therefore, unlikely to affect intragastric drug product performance. Primarily due to the high variability of data in healthy individuals, the potential effects on intragastric pH and surface activity could not be evaluated on a statistical basis. However, based on average (mean and median) values, even if they are statistically significant, it seems unlikely to be of clinical significance. Inter-subject variability of pepsin activity, and total bile acids content was high in both the healthy and the patients’ groups. Statistical investigation of the potential impact of Crohn’s disease on these parameters requires prior designation of the minimum differences to be detected; such differences will determine the minimum sample size required of relevant investigations.
CRISIS MANAGEMENT IN THE MUNICIPALITY – SELECTED ISSUES
Authors: Kostur Krystian
Published: June 2020

Ensuring the safety of citizens is one of the most important functions of the state, as stated in art. 5 of the Polish Constitution of April 2, 1997. The crisis management system is a supplement to the constitutional institution of states of emergency. Appropriate preparation based on planning, an adequate response to a threat by the competent authorities and the fastest possible reversal of the effects of a crisis are the foundations for counteracting threats. Since the first half of the twentieth century, constant attempts have been made to create a comprehensive system guaranteeing an effective response of administrative bodies to threats. Currently, structures and procedures of crisis management as described in the Act of 26 April 2007 on crisis management do not ensure effective implementation of civil protection in the event of emergencies. The subject of the article is the de lege lata statement and formulation of de lege ferenda postulates in the field of crisis management in the municipality
COMPETITIVENESS OF PUBLIC PROCUREMENT UP TO EUR 30,000 (ON THE EXAMPLE OF THE DĄBROWA GÓRNICZA COMMUNE)
Authors: Rokicki Jarosław
Published: June 2020

A wide margin of discretion by a given contracting authority to shape competition rules in procedures not covered by The Provisions of The Public Procurement Law shall give the possibility to strengthen its actions aimed at ensuring competitiveness and transparency. This is reflected in the internal rules set up by the contracting authorities, the design of which shall provide a theoretical framework aimed at ensuring the competitiveness in question. The author, based on the Ordinance of the Mayor of the City introducing the Order Regulations, excluding the Act, has attempted to identify areas that build competitive in procurement. Moreover, he proposed and described the copyright dimensions of the competitiveness, as well as, pointed out measures and indicators enabling the measurement of competitiveness of public procurement.
THE INSTYTUTION OF THE WAIVER OF THE RIGHT TO APPEAL IN GENERAL ADMINISTRATIVE PROCEEDINGS (ART. 127A K.P.A.)
Authors: Śladkowska Ewa
Published: June 2020

The article presents the right to appeal against an administrative decision, which is a relatively new institution, introduced to the Code of Administrative Procedure on June 1, 2017. The article discusses the conditions that determine the recognition of a waiver of an appeal as effective, the legal consequences of the waiver of an appeal, as well as the most important problems regarding the use of this institution. Concise way to regulate this institution in the Code of Administrative Procedure for it raises a lot of ambiguities and causes discrepancies in both doctrine and administrative court rulings. The final part of the article contains general conclusions about the described institution.
FEES GOVERNED BY THE GEOLOGICAL AND MINING LAW IN THE LIGHT OF THE PRINCIPLE OF SUSTAINABLE DEVELOPMENT
Authors: Radecki Gabriel
Published: June 2020

The article evaluates the fees governed by the act of 9 June 2011 Geological and Mining Law using the criteria determined by the directives of the principle of sustainable development. It focuses on subjects and rates of the fees in order as follows: the fees for the prospecting for or exploration of mineral deposits and an underground carbon dioxide storage complex, the exploitation fee and the fees for underground storage of substances, storage of waste, or storage of carbon dioxide. After that the article analyzes more general aspects of problem, connected with application of relevant provisions of the act of 29 August 1997- the Tax Ordinance and with the redistribution of fees. The author came to the conclusion that the fees concentrate on the fiscal function and do not sufficiently contribute to the implementation of the principle of sustainable development.
Correlation of clinico-pathologic data with inflammatory cells infiltration in
colorectal cancer
Authors: Grudzińska M , Jakubowska K , Kańczuga-Koda L , Kisielewski W , Famulski W , Smereczański NM , Lomperta K , Płoński MA. , Rogoz-Jezierska N , Koda M
Published: June 2020

Introduction: Colorectal cancer (CRC) is the third
most common cancer worldwide. At every phase of
cancer development, the inflammatory process has
an important impact. Accurate assessment
inflammatory cells in the tumour environment in
conjunction with clinico-pathologic features can be
a relevant prognostic or predictive parameter.
Purpose: To analyse inflammatory cell infiltration
in CRC tumour mass and correlate with chosen
clinico-pathologic parameters.
Materials and methods: The study group consisted
of 160 patients (64 women, 96 men) diagnosed with
colorectal cancer who underwent surgery. Tissue
material obtained from routine histopathological
diagnosis was stained with H&E and used to assess
the type of inflammatory cells in the invasive front
and centre of the tumour. Results were subjected to
statistical analysis with the age and gender of
patients, tumour localization, tumour growth and
size, TNM stage, adenocarcinoma type, fibrosis,
necrosis, metastasis and tumour invasion (by the
Spearman’s correlation coefficient test).
Results: The presence of neutrophils in the invasive
front of tumour mass was associated with fibrosis
and inflammatory cell infiltration in the invasive
front of tumour. Macrophages in the invasive front
of tumour were found to correlate with tumour
growth (expanding and infiltrate). Macrophages and
eosinophils were associated with inflammatory cell
infiltration in the invasive front and in the centre of
tumour.
Conclusions: The type of inflammatory cells in the
invasive front or centre of the tumour may be useful
to prognoses clinical features of colorectal cancer
Long non-coding RNA and Notch regulation in non-small cell lung cancer
Authors: Pancewicz Joanna
Published: June 2020

Non-small cell lung cancer is one of the most
commonly diagnosed cancer with a very high
mortality rate. Trying to understand the mechanisms
underlying the progression of this type of cancer, it
is necessary to evaluate the changes occurring at
molecular level in cancer cells. Besides the widely
studied signaling pathways and genes which are
dysregulated in NSCLC, there is a large group of
non-coding RNAs involved in cancer pathogenesis.
Those RNAs are tissue specific heterogeneous class
of RNAs that play many functions in physiological
condition in cells, nevertheless current data has
shown that lncRNAs are also functional in different
types of cancer. Moreover, it has been suggest that
lncRNAs are involved in cancer progression by
controlling key signaling pathways involved in
diverse types of tumors. Notch signaling is one of
those pathways, very often deregulated in NSCLC.
Therefore in this review I summarized recent
outcomes according the importance of lncRNAs in
regulation of Notch pathway in the pathogenesis of
NSCLC.
The effect of perceived social support on the quality of life of hemodialysis
patients. A preliminary study.
Authors: Theofilou P , Stefanidou M , Giannakopoulou N , Tzavella F , Zyga S , Tsironi M , Alikari V
Published: June 2020

Purpose: Recent studies have shown that the role
of social support is a predictive factor influencing
the course of the disease. The current study is
focused on patients’ assessment of quality of life
and the relationship of the latter with perceived
social support.
Materials and methods: A total sample of 40
hemodialysis patients voluntarily participated in
this study. Participants were recruited from two
clinics in Athens and have been under
hemodialysis. The measures used were the
Missoula- Vitas Quality of Life Index–15 and the
Multidimensional Scale of Perceived Social
Support. For the data analysis descriptive statistics,
parametric Pearson r test and Non-parametric
Spearman’s rho test were used. Statistical level was
set up at 0.05.
Results: The results of the current study provide
good quality of life of hemodialysis patients and
significant statistical significance between quality
of life in several domains.
Conclusions: This study concludes that the
participants’ assessment of quality of life is poor
regarding the well-being dimension. Also,
perceived social support is significantly related to
quality of life
The effect of the burden of patient care with cancer on family caregivers
Authors: Anterrioti Ch , Alikari Victoria , Kelesi M
Published: June 2020

Cancer is a major problem that affects
today's society. Besides patients suffering from
this disease, cancer has also a huge impact on the
quality of life of the family. This study aimed to
investigate the latest bibliography on the effect of
the burden of patient care with cancer on family
caregivers. Family caregivers face physical health
problems such as physical pain, fatigue, sleep
disturbances. Moreover, several psychological
effects are shown, in which various disorders such
as depression are included. Psychological
disorders, also, include adjustment disorder, panic
disorder, anxiety, and emotional reactions such as
anger, frustration, and fear. In the financial sector,
caregivers face several problems due to the
coverage of medical needs which are reinforced by
reducing or stopping their work because of the
care burden. At the same time, they are confronted
with social impacts in which loneliness and
isolation are attributable to the limitation of their
social activities. As far as the age group of the
patient is concerned, the effects of caring for
young patients are more psychological than
physical in opposite to the older people. The
burden experienced by the family of the cancer
patient exhausts family and it becomes necessary
to identify problems and assess their needs. Health
professionals should strength caregivers with
actions such as psychological support, training,
and participation in social and supportive
programs in order to improve their personal health
and quality of life.
Vitamin C does not improve the efficacy of Helicobacter pylori eradication in
smokers
Authors: Namiot Andrzej , Namiot DB , Bucki R , Kemona A , Kurylonek AJ. , Namiot Z
Published: June 2020

Purpose: To evaluate the hypothesis that vitamin C
improves the efficacy of Helicobacter
pylori eradication in smokers when combined with
pantoprazole, amoxicillin, and clarithromycin.
Materials and methods: The study completed 90
subjects of 98 enrolled, 58 smokers 32 nonsmokers. Helicobacter pylori status was determined
by two methods, CLO test, and histology. Vitamin C
(500 mg) was administered three times daily. The
patients were considered as cured of H. pylori if the
CLO test result and histology were negative 4 weeks
after completion of eradication therapy.
Results: Smokers had lower effectiveness of
eradication therapy than non-smokers and the
administration of vitamin C had not affected the
outcome of eradication therapy.
Conclusions: Vitamin C (500 mg tid) does not
improve the eradication therapy when pantoprazole,
amoxicillin, and clarithromycin were used.
Nannette and Johann Andreas Streicher - their role in shaping musical life in Vienna in the early 19th century
Authors: Maszczyńska Dominika
Published: June 2020

Nannette and Andreas Streicher were important figures in the musical life of Vienna in the early 19th century. The article introduces their profiles, describes the history of their company, their social, cultural and teaching activity as well as different types of artistic activity. It also explains how keyboard instruments shaped sound and aesthetics-related piano ideals at the turn of the 19th century. The versatile activity of the Streichers, which first of all included instrument building, piano play- ing, composition, teaching and organisation of musical life, made a great contribution to Europe’s cultural heritage. We can notice their numerous connections with outstanding figures of musical life of that time, one that deserves particular attention is their acquaintance with Beethoven. Nannette Streicher was an extremely talented builder who not only coped with the typically masculine craft at that time, but she was also significantly successful in that field. Her instruments were popular, earning general recognition, and the innovative solutions introduced by her also influenced the work of other builders and further development of the piano. Their marriage became the basis for a very fruitful cooperation. Andreas’s numerous connections and his familiarity with the community became an important part of the activity of the company and contributed to its development. Nannette and Andreas shared their passion and passed it on to their son Johann Baptist, who successfully continued their piano making tradition and introduced further improvements, earning a great reputation as well. Social, cultural and teaching activities of the Streichers also played an important role in the musical life of Vienna. Andreas Streicher taught his students the secrets of piano technique and apart from that he shaped their musical and aesthetical awareness. His Kurze Bemerkungen are a valuable source of knowledge also for modern-time performers who can – thanks to this text – learn more about the piano playing aesthetics at the turn of the 19th century as well as a number of universal music and performance topics, which remain accurate to this day. Concerts organised in their house had an educational function too, on the one hand they shaped the tastes of music lovers and supported composers, allowing them to present their latest pieces, and on the other hand they contributed to the promotion of young performers for whom concerts there were often the first step leading towards Vienna’s professional musical stage. The development of the topic of the article in this issue of “Notes Muzyczny” is the trans- lation of the text by Andreas Streicher entitled: Some observations on the playing, tuning and maintenance of pianos built in Vienna by Nannette Streicher nee Stein.
Protein intake among healthy adults undertaking regular muscle strength training
Authors: Musiał Kamila , Wiski Marceli , Lipert Anna
Published: June 2020

Background: Protein is a basic macronutrient supplied to the body via food intake and one of the key dietary elements of physically-active populations.
Aim of the study: The aim of the study was to analyze the protein intake of healthy adults undertaking regular muscle strength training.
Material and methods: This study was conducted on 168 healthy adults: 84 women (25.9 ± 6.1 years) and 84 men (25.5 ± 5.4 years) performing strength training on a regular basis (~4 times a week). Protein intake was determined using a structured questionnaire to quantify the amount, source, and frequency of protein consumed.
Results: The participants declared an average daily protein intake of 153.8 ± 50.2 g, with women reporting lower intake (115.9 ± 28.3 g) than men (184.8 ± 42.2 g) (p<0.001). The main sources of protein were poultry meat, dairy products (e.g. milk, eggs), and protein supplements. 79% of participants declared using protein supplements, but no differences between women (79%) and men (80%) were found (p> 0.05). The amount of protein supplied by supplementation was, on average, 37.3 ± 21.5 g with a lesser amount reported by women (28.6 ± 13.2 g) than men (45.5 ± 24.5 g) (p<0.001). 62.9% of participants consumed supplements in the form of whey protein concentrate and 42.6% took protein supplements immediately after training.
Conclusions: The study participants consumed an excess amount of protein in comparison to the recommended daily intake. Protein supplementation accounted for a ¼ of daily protein intake, most often consumed immediately after training and generally in the form of whey protein concentrate. Nutritional education is necessary to align the eating habits and supplemental intake of physically active adults, relative to strength-training demands.
ISSUE TOUCHING SCHOOL QUALITY IN AMHARA REGION
Authors: Agajie Berhanu Asaye
Published: June 2020

The objective of this study was to explore factors that affect quality education in the Amhara region. A descriptive survey method, purposive and stratified random sampling techniques were used to examine research objective. Tools used in collecting data were questionnaire and focused group discussion. The finding showed that positive early experiences and interactions, disciplined school systems, providing an adequate number of teachers, access to toilets, availability of relatively suitable class sizes, welcoming schools boarding atmospheres, learner centered teaching practices , professional mobility and growth were strengths of schools in the region. However, violation conditions, professional inflexibility, incompatible teachers working conditions, irregularity of students’ class attending, lack of life skill curriculums, schoolsfacilities, shortage of instructional materials, clean water supply and not have ongoing trainings have negative impact on quality education. As a result, it is recommended that a further research on quality education, focusing specifically indicators that support a quality primary education.
Da invenção da “fronteira” à crise das expectativas ficcionais sobre o desenvolvimento na região amazônica
Authors: Frizo Pedro , Niederle Paulo
Published: June 2020

Um dos principais projetos encabeçados pelo regime militar brasileiro foi a colonização da Amazônia, que estimulou a ocupação massiva deste território, mobilizando enormes contingentes de indivíduos das mais diferentes regiões do país. O objetivo deste artigo é compreender os mecanismos discursivos para a produção das migrações para a Amazônia, atentando-se à sua produção e sua materialização nas práticas e significações dos atores sociais. A partir da análise de documentos da Biblioteca Nacional do Exército e de entrevistas com assentados do Projeto de Assentamento Dirigido Rio Juma, no município de Apuí, procedeu-se uma análise documental e qualitativa dos textos e das falas dos interlocutores, apoiando-se na análise e agrupamento temático dos dados, a fim de encontrar significações em comum sobre o território e as migrações para o mesmo. Os resultados demonstram que a colonização esteve apoiada na formação e produção de expectativas individuais a partir do discurso estatal, o qual fundamentou a construção de um “futuro imaginado” sobre a Amazônia como território de ascensão social e econômica. Com efeito, concedeu a esta região um significado que legitimou a formação de um regime institucionalizado de espoliação dos seus recursos naturais.
Assessing the Workload of Health Care Practitioners (Moraghebe Salamat) in Urban Health Posts of West Azarbaijan Province in 2017
Authors: Yosefi Mahmood , EntezarMahdi Rasol , Jafari Roghyyeh
Published: June 2020

Background: With the implementation of the health system reform plan and changing the system of providing services in urban areas, a set of cost-effective and prioritized services are provided under the title of the first-level healthcare package as the active services. Therefore, by changing the type and volume of the services and also increasing the coverage of health network system in urban centers, assessing the workload of health care practitioners (Moraghebe Salamat) can affect the quality and quantity of providing services, providing basic data for human resource planning, and implementation of the changes in accordance with new programs. Objectives: This study aimed to assess the workload of family health care providers in urban health posts of the West Azerbaijan province. Methods: This descriptive-analytic and cross-sectional study conducted in 70 urban Health posts in 12 cities of the West Azerbaijan province in 2017. In each Health posts, health care practitioners (Moraghebe Salamat) were observed in 7 hours and 30 minutes of their daily work for 6 consecutive days for 6 weeks (37 working days) by self-report and sampling method. Results: A total of 59,514 people were monitored by 280 urban health care providers. The average time spent on providing health services for each target group was 16 minutes and 51 seconds. The average daily workload of health care providers that work at Health posts with allowing an hour for routine daily needs was 43% of total their workload. Conclusions: With considering to the low workload of health care providers in urban Health posts, in spite of the reforms in the service delivery system in the form of a health system reform plan, in terms of useful time spent working in the workplace, there are adverse conditions in Health posts.
Paraffin Immunofluorescence Increases Light-Chain Detection in Extra-Renal Light Chain Amyloidosis and Other Light-Chain–Associated Diseases
Authors: Gibier Jean-Baptiste , Perbet Romain , Lopez Benjamin , Colombat Magali , Dubois Romain , Humez Sarah , Terriou Louis , Copin Marie-Christine , Gnemmi Viviane
Published: June 2020

Context.—

Distinguishing the different types of amyloid is clinically important because treatments and outcomes are different. Mass spectrometry is the new gold standard for amyloid typing, but it is costly and not widely available. Therefore, immunolabeling remains the first step in identifying the most common types of amyloidosis. In amyloid subtyping, direct immunofluorescence works well when applied to frozen sections, but immunohistochemistry on formalin-fixed, paraffin-embedded material often yields poor results, particularly for light chain amyloidosis. Recently, paraffin immunofluorescence has been described as a valuable salvage technique in renal pathology when frozen sections are not available but it has not been evaluated for extra-renal diseases.

Objectives.—

To evaluate the use of paraffin immunofluorescence for light-chain detection in extra-renal amyloidosis and other light-chain–associated diseases.

Design.—

First, we compared the staining intensity of both light chains between paraffin immunofluorescence and immunohistochemistry on a retrospective cohort of 28 cases of amyloidosis that have been previously typed. Then, we studied the role of paraffin immunofluorescence as an addition to our classical immunohistochemistry panel for amyloidosis typing.

Results.—

In the retrospective cohort, we found that paraffin immunofluorescence outperformed immunohistochemistry for light-chain detection. Then, in the prospective part of the study, we showed that the proportion of correctly classified cases increased from 50% to 71.9% with the adjunction of second-intention paraffin immunofluorescence to the immunohistochemistry procedure.

Conclusions.—

We therefore view paraffin immunofluorescence as a significant addition to the routine workflow for detection of light-chain–related diseases.
RANS Based CFD Investigation of the Interference Between Two Boats Sailing Upwind
Authors: Boehm Christoph , Graf Kai
Published: June 2020

Two sailboats sailing in close proximity will influence each other's wind field. Depending on their relative positions, positive or negative aerodynamic interference may occur. This phenomenon is generally known to sailors and well understood in a qualitative manner. However, it is of great value for aerodynamicists, performance analysts and tacticians to gain a quantitative understanding of this phenomenon. Modern CFD methods allow extensive flow visualization and are therefore helpful to improve our understanding of flow interference.

This paper describes the results of numerical simulations of the aerodynamic interference of two Elliot 6m sailboats sailing upwind. The simulations were performed using methods based on the solution of the Reynolds Averaged Navier Stokes Equations, so called RANSE-solvers. A broad range of relative positions of the two sailboats were investigated and the differences in boat speed were quantified. The results show that, for a situation where the two boats sail directly abeam of each other, neither of them has an advantage. However, for a situation where the boats sail even with respect to a regatta start line, the leeward boat is able to achieve a quite large speed advantage of 0.2 knots.
Development of a Sailing-Specific Pose Capture Method To Measure Dynamic Sailor Loadings
Authors: Taylor J. C. , Banks J. , Taunton D. , Turnock S. R. , Hudson D.
Published: June 2020

Research into the dynamics of sailing vessels, most notably yachts, has led to the development of sophisticated models including the unsteady aero and hydrodynamics and even sailor's tactics. However, the time-varying loadings caused by a sailor's motions have typically been neglected in velocity prediction programs (VPPs). When applied to the assessment of sailing dinghy performance, the position and motions of the crew are significant but impractical to measure mechanically. A sailing-specific pose capture method to determine the sailor loadings using orientation sensors and a model of the sailor's mass distribution is presented. The accuracy of the hiking moment estimate was evaluated using laboratory-based measurements. The estimated hiking moment exhibits excellent dynamic tracking of the measured moment. The method is used to measure on-water hiking moment for the first time and the results are discussed. The proposed method provides a platform to analyze and model how sailor-generated forces interact with the sailboat to affect boat speed. This can be used alongside realistic modelling of the wind and wave loadings to extend existing time-domain dynamic velocity prediction programs (DVPPs). This opens a new area of sailing research as the human can now be modelled to respond to force perturbations.
Pressure Measurements on Yacht Sails: Development of a New System For Wind Tunnel and Full Scale Testing
Authors: Fossati Fabio , Bayati Ilmas , Muggiasca Sara , Vandone Ambra , Campanardi Gabriele , Burch Thomas , Malandra Michele
Published: June 2020

The paper presents an overview of a joint project including Politecnico di Milano, CSEM and North Sails, aiming at developing a new sail pressure measurement system based on MEMS sensors (an excellent compromise between size, performance, costs and operational conditions) and pressure strips and pads technology. These devices were designed and produced to give differential measurement between the leeward and windward side of the sails. The research has been developed for the final employment on the Lecco Innovation Hub Sailing Yacht Lab, a 10 m length sailing dynamometer which aims at being the reference contemporary full scale measurement device in the sailing yacht engineering research field, to enhance the insight of sail steady and unsteady aerodynamics.

The pressure system is described in details, the data acquisition process and system metrological validation are reported; furthermore, some results obtained during a wind tunnel campaign carried out at Politecnico di Milano Wind Tunnel, as a benchmark of the whole measuring system for future full scale application, are reported and discussed in details.

Moreover, the system configuration for full scale testing, which is being finalized at the time of this paper, is also described
Art Amid Science: Retaining the Role of 'the Designer's Eye' in Innovative Performance Yacht Design
Authors: Shaw Robert
Published: June 2020

Increasingly, the dominance of engineering processes in yacht design development imposes limitations on the possibilities and scope for creative design. This paper explores an alternative methodological framework for yacht design that has innovation as its central concern. The method presented encourages innovation by blending the empirical knowledge obtained through scientific techniques with experiential wisdom and artistic input. It focuses on meeting the key criteria of user experience, performance and handling characteristics, and argues that in a field increasingly dominated by mathematical models and computer-based analysis, there remains a powerful role for the harder-to-quantify role of art in the creation of high-performance yachts. Finally, a case study of the development of the Shaw 11 metre Little Nico provides a platform to both explore and evaluate this alternative methodology in practice.
Modelling and Control of a Tethered Kite In Dynamic Flight
Authors: Cadalen Baptiste , Griffon Fabien , Lanusse Patrick , Sabatier Jocelyn , Parlier Yves
Published: June 2020

The need to reduce CO2 emissions and the increase in oil prices affect all transportation industries and especially the maritime industry. This has led to the search for more energy-saving propulsion systems for ships. Taking advantage of wind energy by using tethered airfoils, or kites, as an alternative propulsion source can be an effective solution. The " Beyond The Sea" project, led by Yves Parlier, aims to provide ships with an alternative green energy source. An automatic pilot was designed in order to control a kite that can generate enough power to tow a ship. To this end, a point mass model was first used to describe the kite dynamics. The model parameters were deduced from experimental data and the aerodynamic coefficients were identified using data from a quasi-static flight. Open loop simulations were conducted to verify the kite behaviour and the overall coherence of the model. An eight-shaped trajectory was defined on the wind window. Its position, size, orientation and direction are all adjustable parameters. A path-following strategy was then designed. It computes an error signal between the kite velocity orientation and a desired velocity orientation ensuring that the kite is steered towards and along the trajectory. Closed-loop simulations are presented to show the efficiency of the path-following algorithm, and the various theoretical performances obtained depending on the chosen trajectory are discussed.
Staphylococcus argenteus as an etiological agent of prosthetic hip joint infection: a case presentation
Authors: Söderquist Bo , Wildeman Peter , Stenmark Bianca , Stegger Marc
Published: June 2020

Abstract. This report presents a case of prosthetic hip infection caused by Staphylococcus argenteus, a potentially overlooked etiology of prosthetic joint infections (PJIs). Whole-genome sequencing showed that the S. argenteus isolate was an ST2250 and clustered within other CC2250 isolates, the largest clonal group of S. argenteus. This sequence type is prevalent and may be associated with invasive infections. The present isolate was phenotypically fully susceptible to all tested antimicrobial agents and genome analysis did not detect any resistance genes, nor were any staphylococcal cassette chromosome residues detected. Despite initial appropriate management with debridement and biofilm-active antibiotics, the outcome was unfavorable with recurrence and a persistent infection treated with suppressive antibiotics. Regarding the repertoire of genomic traits for virulence in S. argenteus, PJIs caused by this bacterium should be treated accordingly as Staphylococcus aureus PJIs.
A propósito de la reforma de la legislación española en materia de capacidad jurídica: la voluntariedad como nota esencial del apoyo
Authors: Martínez Pujalte Antonio Luis
Published: June 2020

En septiembre de 2018, el Gobierno de España inició la tramitación de una profunda reforma de nuestra legislación civil, que supondrá un cambio radical del régimen de la capacidad jurídica. En estas páginas se analiza la propuesta de reforma en relación con un aspecto concreto: la voluntariedad en la constitución de las instituciones de apoyo al ejercicio de la capacidad jurídica. Se examina si la Convención de la ONU permite establecer medidas de apoyo que no sean conformes con la voluntad de la persona; las conclusiones obtenidas permiten, a continuación, examinar la conformidad con la Convención de la reforma proyectada.
Jurisprudencia comparada sobre aborto: cuando los feminismos impregnan el derecho.
Authors: Gonzalez Prado Patricia
Published: June 2020

Analizo críticamente la jurisprudencia sobre aborto de la Corte de los Estados Unidos, el Tribunal Constitucional Español, la Corte Suprema Mexicana y la Corte Suprema Colombiana. Indago los conflictos de derecho que estructuran estos pronunciamientos, las instituciones jurídicas en las que fundan las respuestas a dichos conflictos, y las continuidades y rupturas del reconocimiento del derecho a abortar. Me interesan las contribuciones feministas que las sentencias incorporan y la producción, desde los feminismos, de los argumentos que permiten el abandono del punitivismo en materia de interrupción del embarazo y la estructuración del reconocimiento de esta expresión de la autonomía sexual.
La obligación de poner en conocimiento: la función pública ante la prevención, detección e intervención frente al acoso sexual en las universidades españolas.
Authors: Madrid Pérez Antonio
Published: June 2020

Durante los últimos años, las universidades españolas han desarrollado Protocolos para la prevención y la actuación frente al acoso sexual y por razón de orientación sexual. Una parte de estos Protocolos establece que los empleados públicos están obligados a poner en conocimiento de las autoridades universitarias la existencia de casos de acoso. Sin embargo, la mayor parte de los Protocolos omite esta obligación. En este artículo se analiza esta disparidad normativa. También se analizan los criterios legales y jurisprudenciales que fundamentan que los Protocolos hayan de incorporar la obligación de comunicar de los empleados públicos, como una obligación diferenciada de la obligación de denunciar.
Índice de autores/as y estadísticas del número
Authors: Gascón-Cuenca Andrés
Published: June 2020

Índice de autores/as y estadísticas del número
Oídos a pares. Un proyecto de tutoría entre iguales para el desarrollo de la afinación y la percepción auditiva en el alumnado de violín y viola
Authors: Fernández Barros Andrea , Viladot Laia , Duran David
Published: June 2020

Son múltiples los estudios en los últimos años que señalan la música como una actividad plenamente colaborativa, con las ventajas que esto conlleva. El presente artículo presenta “Oídos a pares”, un proyecto de innovación didáctica basado en el aprendizaje cooperativo para el desarrollo de la afinación y percepción auditiva del alumnado de violín y viola. La innovación didáctica consiste en el uso de la tutoría entre iguales recíproca, parejas de discentes con una relación asimétrica, que aprenden enseñándose, partiendo de un objetivo común, conocido y compartido. Todo ello, a través de un marco de interacción estructurado por el profesorado y un material didáctico específico. Para ello, se ha diseñado e implementado una experiencia con 10 estudiantes de violín y viola de Enseñanzas Elementales. El artículo pone en relieve el potencial de la tutoría entre iguales en la educación musical, señala elementos concretos que deben considerarse para aprovechar al máximo esta herramienta y muestra un ejemplo de la experiencia llevada a cabo. Los resultados indican que este proyecto resultó ser una experiencia positiva, evidenciando que, a pesar de ser una práctica poco explorada, puede ser una opción valiosa para la educación musical.
Educación musical performativa en la formación de intérpretes. Un estudio de caso
Authors: Ramirez Martinez Maria Fernanda , Rodríguez-Quiles José Antonio
Published: June 2020

La educación musical postmoderna viene reclamando la utilización de nuevos modos de conceptualizar los procesos de enseñanza-aprendizaje que hagan más significativos y eficaces los procesos de apropiación y empoderamiento musicales, utilizando para ello herramientas derivadas de la música moderna, del aprendizaje rizomático o del propio contexto social de los participantes. Gracias a esto surgen, entre otras propuestas pedagógicas, el Aprendizaje Musical Informal y la Educación Musical Performativa. La presente investigación es un estudio de caso sobre clases instrumentales colectivas en una institución superior de música de España y de cómo sus prácticas metodológicas se aproximan a las arriba mencionadas, teniendo como base un ambiente de aprendizaje flexible y democrático que repercute de forma significativa en la formación de futuros músicos profesionales.
SCANDINAVIAN CRIME FICTION AND POPULAR CULTURE: JO NESBØ'S HARRY HOLE NOVELS
Authors: Kovačević Darko М.
Published: June 2020

Jo Nesbø is one of the most important and popular crimefiction writers of today, as well as a typical representative of thecontemporary literary genre known as Scandinavian crime fiction.Within the entire literary opus of this writer, the central positionis reserved for the series of novels in which detective Harry Hole isthe main character. Various segments and aspects of these novelsdemonstrate a strong connection and relation with popularculture, and they are identified and discussed in this article.However, before the mentioned identification and discussion,some facts are stated regarding the phenomena of Scandinaviancrime fiction, as a regionally determined literary genre whichemerged to the world literature scene in full power at the end ofthe 20th and the first decades of the 21st century, and its relation topopular culture.
ПОЛОЖАЈ СРПСКЕ НАЦИОНАЛНЕ МАЊИНЕ У РУМУНИЈИ
Authors: Стојановић Иван М.
Published: June 2020

У раду се кроз интердисциплинарни приступ и кроз двапоглавља, разматра историјски и савремени положај српске на-ционалне заједнице (мањине) на територији данашње Румуније.Полази се од општих историјских прилика и временских раз-добља (од најранијег средњовековног до савременог периода) укојима Срби живе на овом простору. Одговара се на питања какоје српска заједница услед многих промена, државних и поли-тичких уређења, различитих фаза интеграција (адаптација,акултурација, асимилација) успела да заслугом многих својихсународника дâ велики допринос друштву и опстане до данас,када важи за једну од најорганизованијих заједница ван матичнедржаве. У другом поглављу разматра се демографска слика,вероисповест и црквена организација, језик и школство, кул-турна баштина и живот, као и политичко деловање.
ЗНАЧАЈ И УЛОГА ИРАЦИОНАЛНИХ ЧОВЕКОВИХ СНАГА У УМЕТНОСТИ И КУЛТУРИ
Authors: Вилић Наташа С.
Published: June 2020

Иако рана модерност наглашава веру у разум и рацио-налне снаге у човеку, касни модерни мислиоци и уметници до-лазе до револуционарних увида да управо ирационалне силе учовеку јесу главне покретачке снаге у његовом целокупномстваралачком опусу. Уметници и философи схватају да разумима ограничавајућу улогу на човеково делање и понашање и данису једини који га детерминишу, него да нагони, страсти,инстинкти се налазе у самој природи човека и као такви битнога одређују. Овим се отвара проблем ирационалног који се, крозстваралаштво уопште, показује у својој сложености и вишеслој-ности. Ниче први јасно на ово указује. Претерани рационализами интелектуализација доводе до уништења спонтаности којепокрећу културу и уметничко стваралаштво и вољу за прокреа-цијом. Човек мора изнова у себи да пробуди инстинктивне ко-рене властитог постојања. Дионисијски дух укорењен је у ира-ционалном и он је извор креативности. Из тог разлога, сматраНиче, неки уметници ближи су истини од појединих философа.Криза духа у којој се налази човек може се решити само ако сечовек суочи сам са собом и ослободи се свега онога што спутаваживот. Такво једно (само)преиспитивање могуће је и прекоуметности. Уметност постаје спас од истине. А уметник је тајкоји афирмише живот тако што га демистификује. То су ура-дили бројни уметници, међу њима и сам Достојевски, који је усвоме уметничком раду допро до најдубљих и најтамнијих де-лова човекове душе. Тиме је заправо ослободио човека свегаонога што га је ограничавало да буде што јесте. С друге стране,Фројд, као и Јунг, наглашавају значај и улогу несвесних сила учовеку. Фројд не глорификује те силе, него указује на њихове(аутодеструктивне) снаге погубне како по човека тако и по свеоно већ створено.