bluuebunny/crossref_metadata_2025 huggingface dataset:
A new holistic exploratory approach to Systems Biology by Near Infrared Spectroscopy evaluated by chemometrics and data inspection
Authors: Munck Lars
Published: September 2007

There is a need for an improved biological and theoretical interpretation of Near Infra‐Red Spectral (NIRS) fingerprints from tissues that could contribute with holistic overview to fine‐grained detail modelled in Systems Biology. The concept of gene expression in self‐organised networks was experimentally tested in a barley endosperm model with molecularly defined and undefined mutants. Surprisingly reproducible gene‐specific NIRS fingerprints were observed directly in log1/R MSC pre‐treated spectra that could not be accurately represented by destructive mathematical models. A mutant spectrum in an isogenic background represents the physiochemical expression of the gene in the whole network (tissue). The necessary holistic overview that is needed experimentally to introduce Ilya Prigogine's theory on self‐organisation in Systems Biology was supplied by defining the spectral phenome. Interval spectral information on genotypes and environment was classified by interval Extended Canonical Variates Analysis (iECVA). Genetic changes in spectra were interpreted by interval Partial Least Squares Regression (iPLSR) correlations to chemical variables. A new pathway regulation was detected. The finely grained ‘bottom up’ modelling of molecular and chemical data from pathways requires a coarsely grained exploratory ‘top down’ overview by NIRS to account for the outcome of self‐organisation. The amplification of expression from a gene to the phenome (pleiotropy) can now for the first time be quantified as a whole reproducible phenomenological pattern by NIRS and compared to other gene spectra. It explains published findings that transformed respectively mutated genes in genetically modified organisms (GMOs) and cancer patients can be detected unsupervised from tissues by spectroscopy, chemometrics and data inspection. Copyright © 2007 John Wiley & Sons, Ltd.
Porphyrin Light‐Harvesting Arrays Constructed in the Recombinant Tobacco Mosaic Virus Scaffold
Authors: Endo Masayuki , Fujitsuka Mamoru , Majima Tetsuro
Published: September 2007

We have demonstrated the construction of multiple porphyrin arrays in the tobacco mosaic virus (TMV) supramolecular structures by self‐assembly of recombinant TMV coat protein (TMVCP) monomers, in which Zn‐coordinated porphyrin (ZnP) and free‐base porphyrin (FbP) were site‐selectively incorporated. The photophysical properties of porphyrin moieties incorporated in the TMV assemblies were also characterized. TMV–porphyrin conjugates employed as building blocks self‐assembled into unique disk and rod structures under the proper conditions as similar to native TMV assemblies. The mixture of a ZnP donor and an FbP acceptor was packed in the TMV assembly and showed energy transfer and light‐harvesting activity. The detailed photophysical properties of the arrayed porphyrins in the TMV assemblies were examined by time‐resolved fluorescence spectroscopy, and the energy transfer rates were determined to be 3.1–6.4×109 s−1. The results indicate that the porphyrins are placed at the expected positions in the TMV assemblies.
Peri‐ and Enantioselectivity of Thermal, Scandium‐, and [Pybox/Scandium]‐Catalyzed Diels–Alder and Hetero‐Diels–Alder Reactions of Methyl (E)‐2‐Oxo‐4‐aryl‐butenoates with Cyclopentadiene
Authors: Desimoni Giovanni , Faita Giuseppe , Toscanini Marco , Boiocchi Massimo
Published: September 2007

The cycloaddition between methyl (E)‐2‐oxo‐4‐aryl‐3‐butenoates (2 a–d) and cyclopentadiene, in addition to the expected normal Diels–Alder (DA) adducts endo‐3 a–d and exo‐4 a–d, gives the less expected endo‐5 a–d products of the [4+2] hetero‐Diels–Alder (HDA) reaction in which the α‐ketoester behaves as a heterodiene. If a comparison is made between the thermal and the scandium(III) triflate‐catalyzed conditions, the periselectivity changes and whereas under thermal conditions the main products are those from the DA reaction (3 a–d), in the presence of Sc(OTf)3 (OTf=triflate), the HDA products 5 a–d become largely predominant. The reactions are enantioselectively catalyzed by the scandium(III) triflate complex of (4′S,5′S)‐2,6‐bis[4′‐(triisopropylsilyl)oxymethyl‐5′‐phenyl‐1′,3′‐oxazolin‐2′‐yl]pyridine (1) and both the DA and the HDA products are obtained with excellent enantiomeric excess, up to >99 % ee. The X‐ray crystallographic structure determination of 5 c assigns it the 4R,4aS,7aR absolute configuration. The thermal retro‐Claisen rearrangement of 3 c into (4R,4aS,7aR)‐5 c allows the correlation of their absolute configuration, and 3 c has therefore the 2R,3R configuration. By analogy the same absolute configuration can be assigned to 3 a,b,d and 5 a,b,d, and the stereospecific thermal Claisen rearrangement of the optically active 5 a,b,d into 3 a,b,d completes the correlation between their absolute configuration. The [3,3]‐sigmatropic rearrangements can be easily carried out under catalytic conditions with scandium(III) triflate, which promotes the equilibration between 3 a–d and 5 a–d, with a different degree of enantioselectivity characterizing the process starting from 3 a–d or 5 a–d. The unambiguous attributions of the configuration to the products allows us to propose a rationale of the stereochemical outcome of the catalyzed cycloaddition and to investigate the reaction mechanism of the competing DA and HDA reactions and shifts in products distribution by acid catalysis.
Platinum Fluorides Beyond PtF6?
Authors: Riedel Sebastian
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ce2Ru2In3 and Ce3Ru2In2: Site Exchange in Ternary Indides of a New Structure Type.
Authors: Tursina A. I. , Kurenbaeva Zh. M. , Gribanov A. V. , Noel H. , Roisnel T. , Seropegin Y. D.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Crystal Structure of the Ternary Ln3Ag4Sn4 Stannides (Ln: Y, Gd, Tb, Dy, Ho) with Gd3Cu4Ge4‐Type Structure.
Authors: Romaka V. V. , Davydov V. , Gladyshevskii R. , Melnychenko N.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ba5Al2Ge7 and Ba7Al4Ge9: Two New Intermetallic Phases with Unusual Al—Ge Anions.
Authors: Wendorff Marco , Roehr Caroline
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Crystal Structure, Vibrational Spectrum and Thermal Behavior of the Ammonium Hexathiohypodiphosphate Dihydrate (NH4) 4P2S6×2H2O.
Authors: Gjikaj Mimoza , Brockner Wolfgang
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structure, Thermal Stability and Magnetostrictive Properties of PrFex (1.5 ≤ x ≤ 3.0) Alloys.
Authors: Shi Y. G. , Tang S. L. , Huang Y. J. , Nie B. , Qian B. , Lv L. Y. , Du Y. W.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thermomagnetic Properties Near Transitions of Tb6FeX2 (X: Sb, Bi).
Authors: He Wei , Zhang Jiliang , Zeng Lingmin , Qin Pingli , Cai Gemei
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isothermal Section at 900 °C of the Ce—Fe—Si Ternary System.
Authors: Berthebaud D. , Tougait O. , Potel M. , Noel H.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heat‐Induced Alterations in the Surface Population of Metal Sites in Bimetallic Nanoparticles.
Authors: Hwang Bing‐Joe , Sarma Loka Subramanyam , Wang Guo‐Rung , Chen Ching‐Hsiang , Liu Din‐Goa , Sheu Hwo‐Shuenn , Lee Jyh‐Fu
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Tungstogermanate [Ce20Ge10W100O376 (OH)4(H2O)30]56‐: A Polyoxometalate Containing 20 Cerium(III) Atoms.
Authors: Bassil Bassem S. , Dickman Michael H. , Roemer Isabella , von der Kammer Bernd , Kortz Ulrich
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Structure and Third‐Order Nonlinear Optical Properties of a Iodoargentate(I) Cluster Polymer of [(Et4N)(Ag2I3)]n.
Authors: Zhang Z. X. , Li Y. , Li K. C. , Song W. D. , Wang C. , Pan L. Y.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kinetic Resolution of Racemic Alcohols Catalyzed by Minimal Artificial Acylases Derived from L‐Histidine.
Authors: Kosugi Yuji , Akakura Matsujiro , Ishihara Kazuaki
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Air‐Stable P‐Chiral Bidentate Phosphine Ligand with (1‐Adamantyl)methylphosphino Group.
Authors: Imamoto Tsuneo , Kumada Atsushi , Yoshida Kazuhiro
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mixtures of Chiral Phosphorous Acid Diesters and Achiral P Ligands in the Enantio‐ and Diastereoselective Hydrogenation of Ketimines.
Authors: Reetz Manfred T. , Bondarev Oleg
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Pyrazolines via 1,3‐Dipolar Cycloadditions of Heterocyclic Isopropenes.
Authors: Zhang Xuqing , Ng Raymond , Lanter James , Sui Zhihua
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Formic Acid Oxidatively Cleaves 1,2,3,4‐Tetraaryl‐2‐butene‐1,4‐diones to 1,2‐Diaryl‐1,2‐ethanediones under Microwave Irradiation.
Authors: Rao H. Surya Prakash , Jothilingam S. , Vasantham K. , Scheeren Hans W.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Observation of New Cycloisomerization Pattern of 1,5‐Bisallenes. Catalyst and Substituent Effects.
Authors: Lu Ping , Ma Shengming
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Factors Influencing the Selectivity in Asymmetric Oxidation of Sulfides Attached to Nitrogen Containing Heterocycles.
Authors: Seenivasaperumal Muthu , Federsel Hans‐Juergen , Ertan Anne , Szabo Kalman J.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Epoxidation of Conjugated cis‐Enynes by Chiral Dioxirane.
Authors: Burke Christopher P. , Shi Yian
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Organocatalysis of Epoxidation by Iminium Salts under Non‐Aqueous Conditions.
Authors: Page Philip C. Bulman , Buckley Benjamin R. , Barros David , Blacker A. John , Marples Brian A. , Elsegood Mark R. J.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Active Role of NHC Ligands in Platinum‐Mediated Tandem Hydroboration—Cross Coupling Reactions.
Authors: Lillo Vanesa , Mata Jose A. , Segarra Anna M. , Peris Eduardo , Fernandez Elena
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Continuous Flow Ligand‐Free Heck Reactions Using Monolithic Pd(0) Nanoparticles.
Authors: Nikbin Nikzad , Ladlow Mark , Ley Steven V.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Room Temperature Ionic Liquids: New Solvents for Schrock′s Catalyst and Removal Using Polydimethylsiloxane Membranes.
Authors: Miller A. Lee II , Bowden Ned B.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Conversion of Tertiary Alcohols to tert‐Alkyl Azides by Way of Quinone‐Mediated Oxidation—Reduction Condensation Using Alkyl Diphenylphosphinites.
Authors: Kuroda Kiichi , Hayashi Yujiro , Mukaiyama Teruaki
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Organocatalytic Singly Occupied Molecular Orbital Activation: The Enantioselective α‐Enolation of Aldehydes.
Authors: Jang Hye‐Young , Hong Jun‐Bae , MacMillan David W. C.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Gold‐Catalyzed Efficient Preparation of Linear α‐Iodoenones from Propargylic Acetates.
Authors: Yu Meng , Zhang Guozhu , Zhang Liming
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Functionalized 1‐Azadienes by Reaction of 2,6‐Dimethylphenyl Isocyanide and Acetylenic Esters in the Presence of CH Acids.
Authors: Yavari Issa , Karimi Elham
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Joint Experimental and Theoretical Study of the Palladium‐Catalyzed Electrophilic Allylation of Aldehydes.
Authors: Piechaczyk Olivier , Cantat Thibault , Mezailles Nicolas , Le Floch Pascal
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselectively Organocatalytic Michael Addition of Ketones to Alkylidene Malonates.
Authors: Cao Chun‐Li , Sun Xiu‐Li , Zhou Jiao‐Long , Tang Yong
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Method for Dehydration Condensation Using Pyridine‐3‐carboxylic Anhydride (3‐PCA): Synthesis of Carboxamides from Nearly Equimolar Amounts of Carboxylic Acids and Amines.
Authors: Funasaka Setsuo , Mukaiyama Teruaki
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Copper(I)‐Catalyzed Homocoupling of Aryldiazonium Salts: Synthesis of Symmetrical Biaryls.
Authors: Cepanec Ivica , Litvic Mladen , Udikovic Josipa , Pogorelic Ivan , Lovric Marija
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Phosphine Oxides as Stabilizing Ligands for the Palladium‐Catalyzed Cross‐Coupling of Potassium Aryldimethylsilanolates.
Authors: Denmark Scott E. , Smith Russell C. , Tymonko Steven A.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Palladium‐Catalyzed Addition of Aryl‐ and Heteroarylboronic Acids to Aldehydes.
Authors: Qin Changming , Wu Huayue , Cheng Jiang , Chen Xi'an , Liu Miaochang , Zhang Weiwei , Su Weike , Ding Jingchang
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rh‐Catalyzed [4 + 2] Carbocyclization of Vinylarylaldehydes with Alkenes and Alkynes Leading to Substituted Tetralones and 1‐Naphthols.
Authors: Tanaka Ken , Hojo Daiki , Shoji Takeaki , Hagiwara Yuji , Hirano Masao
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Titanium‐Catalyzed Asymmetric Epoxidation of Non‐Activated Olefins with Hydrogen Peroxide.
Authors: Sawada Yuji , Matsumoto Kazuhiro , Katsuki Tsutomu
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Direct Access to N‐H‐Aziridines from Asymmetric Catalytic Aziridination with Borate Catalysts Derived from Vaulted Binaphthol and Vaulted Biphenanthrol Ligands.
Authors: Lu Zhenjie , Zhang Yu , Wulff William D.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Structure Activity Relationship Studies of Benzothieno[3,2‐b]furan Derivatives as a Novel Class of IKKβ Inhibitors.
Authors: Sugiyama Hideyuki , Yoshida Masato , Mori Kouji , Kawamoto Tomohiro , Sogabe Satoshi , Takagi Terufumi , Oki Hideyuki , Tanaka Toshimasa , Kimura Hiroyuki , Ikeura Yoshinori
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Reduction of N‐(tert‐Butoxycarbonyl)indoles by Polymethylhydrosiloxane.
Authors: Chandrasekhar Srivari , Basu Debjit , Reddy Ch. Raji
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of Hydrazonoyl Chlorides to Trimethylsilyl Homoallyl Ethers.
Authors: Del Buttero Paolo , Molteni Giorgio , Mondini Sara , Ponti Alessandro
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Regioselective Route to 5‐Substituted Pyrazole‐ and Pyrazoline‐3‐phosphonic Acids and Esters
Authors: Conti P. , Pinto A. , Tamborini L. , Rizzo V. , De Micheli C.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Improved Synthesis of 3‐Methyl‐4‐nitro‐5‐heteroarylethenylisoxazoles.
Authors: Adamo Mauro F. A. , Duffy Eleanor F. , Konda Vivekananda R. , Murphy Finbar
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile Protection of Carbonyl Compounds as Oxathiolanes and Transoxathioacetalization of Oxyacetals Promoted by Iron(III) Trifluoroacetate or Trifluoromethanesulfonate as Chemoselective and Recyclable Catalysts.
Authors: Adibi Hadi , Jafari Hadi
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient 2‐Amino‐2‐thiazolin‐4‐ones or 2‐Iminothiazolidin‐4‐ones Formation from Thioureas and Maleimides under Solvent‐Free Conditions.
Authors: Shimo Tetsuro , Matsuda Yuki , Iwanaga Tetsuo , Shinmyozu Teruo , Somekawa kenichi
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New 5‐Substituted Thiazolo[3,2‐b][1,2,4]triazol‐6‐ones: Synthesis and Anticancer Evaluation.
Authors: Lesyk Roman , Vladzimirska Olena , Holota Serhiy , Zaprutko Lucjusz , Gzella Andrzej
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Aromatic Spiroacetals Related to γ‐Rubromycin Based on a 3H‐Spiro[1‐benzofuran‐2,2′‐chroman] Skeleton.
Authors: Tsang Kit Yee , Brimble Margaret A.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Diarylpyrimidine Analogues of TMC278 and Their Antiviral Activity Against HIV‐1 Wild‐Type and Mutant Strains.
Authors: Guillemont Jerome , et al. et al.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Straightforward Preparation of Fluorine‐Containing 1,2‐Dihydropyrimidines and Pyrimidines with 2,2‐Dihydropolyfluoroalkylaldehydes.
Authors: Yang Xian‐Jin , Zhang Li‐Si , Liu Jin‐Tao
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preparation of a 7‐Arylthieno[3,2‐d]pyrimidin‐4‐amine Library.
Authors: Peng Jinsong , Lin Wenqing , Jiang Dahong , Yuan Shixue , Chen Yuanwei
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 2‐Benzothienyl Carbonyl 4‐Arylpiperazines as Novel Delaviridine Analogues.
Authors: Pessoa‐Mahana Hernan , Acevedo R. Rodrigo , Saitz B. Claudio , Araya‐Maturana Ramiro , Pessoa‐Mahana C. D.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Step Synthesis of Oxazoline and Dihydrooxazine Libraries.
Authors: Chaudhry Priyanka , Schoenen Frank , Neuenswander Benjamin , Lushington Gerald H. , Aube Jeffrey
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Lewis Acid Mediated SN2‐Type Nucleophilic Ring Opening Followed by [4 + 2] Cycloaddition of N‐Tosylazetidines with Aldehydes and Ketones: Synthesis of Chiral 1,3‐Oxazinanes and 1,3‐Amino Alcohols.
Authors: Ghorai Manas K. , Das Kalpataru , Kumar Amit
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Azinyl Sulfides. Part 94. Synthesis of New Pentacyclic Diquinothiazines.
Authors: Nowak Malgorzata , Pluta Krystian , Suwinska Kinga , Straver Leo
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 3‐Alkoxy‐5,6‐dihydro‐4H‐1,2,5‐oxadiazines from Alkyl α‐Aminohydroximates.
Authors: Kurz Thomas , Thimann Wolfgang , Geffken Detlef
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Syntheses and Antibacterial Activity of Phendioxy Substituted Cyclic Enediynes.
Authors: Joshi Mukesh Chandra , Bisht Gopal Singh , Rawat Diwan S.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Synthesis of Allylsilanes Bearing Tertiary and Quaternary Si‐Substituted Carbons Through Cu‐Catalyzed Allylic Alkylations with Alkylzinc and Arylzinc Reagents.
Authors: Kacprzynski Monica A. , May Tricia L. , Kazane Stephanie A. , Hoveyda Amir H.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Easy and Stereoselective Synthesis of Cyclopropyl‐Substituted Phosphonates via α‐Chlorophosphonates.
Authors: Kumar Swamy K. C. , Pavan Kumar K. V. P. , Rama Suresh R. , Satish Kumar N.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Convenient Approach to λ5‐Phosphinines via Interaction of Phosphorylated 3‐Pyrrolidinocrotonitrile with 2‐Bromoacetophenones.
Authors: Svyaschenko Yurii V. , Kostyuk Alexandr N. , Barnych Bogdan B. , Volochnyuk Dmitriy M.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
[2 + 3]Cycloaddition Reaction of a Kinetically Stabilized Distibene with a Nitrile Oxide Leading to the Formation of a Unique Heterocyclic Compound.
Authors: Sasamori T. , Mieda E. , Nagahora N. , Tokitoh N.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Wuweizidilactones A—F: Novel Highly Oxygenated Nortriterpenoids with Unusual Skeletons Isolated from Schisandra chinensis
Authors: Sun Han‐Dong , et al. et al.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isolation and Characterization of Biogenetically Related Highly Oxygenated Nortriterpenoids from Schisandra chinensis.
Authors: Huang Sheng‐Xiong , Li Rong‐Tao , Liu Jing‐Ping , Lu Yang , Chang Ying , Lei Chun , Xiao Wei‐Lie , Yang Li‐Bin , Zheng Qi‐Tai , Sun Han‐Dong
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Concise Synthesis of Two Trisaccharide Analogues Related to the Glycone Constituent of Phanoside, a Novel Insulin Releasing Natural Product.
Authors: Agnihotri Geetanjali , Mandal Pintu Kumar , Misra Anup Kumar
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
First Synthesis and Antimicrobial Activity of N‐ and S‐α‐L‐Arabinopyranosyl‐1,2,4‐triazoles.
Authors: Khalil Nasser S. A. M.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis and Structure Revision of the Marine Metabolite Palmerolide A.
Authors: Jiang Xin , Liu Bo , Lebreton Sylvain , De Brabander Jef K.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of the Potent Antitumor Macrolides Pladienolide B (Ia) and D (Ib).
Authors: Kanada Regina M. , Itoh Daisuke , Nagai Mitsuo , Niijima Jun , Asai Naoki , Mizui Yoshiharu , Abe Shinya , Kotake Yoshihiko
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Lactam Analogue of 4‐epi‐Brefeldin A.
Authors: Paek Seung‐Mann , Seo Seung‐Yong , Min Kyung‐Hoon , Shin Dong Mok , Chung Young Keun , Suh Young‐Ger
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
N‐Methylpseudoephedrine‐Mediated Asymmetric Synthesis of O‐Carboxyalkylated Flavones.
Authors: Kang Kyoung Hee , Heo Ji Hyeon , Kim Yongtae , Park Yong Sun
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Concise Synthesis of Dideoxy‐epigallocatechin Gallate (DO‐EGCG) and Evaluation of Its Antiinfluenza Virus Activity.
Authors: Furuta Takumi , Hirooka Yasuo , Abe Ayako , Sugata Yusuke , Ueda Mitsuru , Murakami Kouki , Suzuki Takashi , Tanaka Kiyoshi , Kan Toshiyuki
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
SwiFT: An Index Structure for Reduced Graph Descriptors in Virtual Screening and Clustering.
Authors: Fischer J. Rpbert , Rarey Matthias
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mining of Randomly Generated Molecular Fragment Populations Uncovers Activity‐Specific Fragment Hierarchies.
Authors: Batista Jose , Bajorath Juergen
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rapid Estimation of Relative Protein—Ligand Binding Affinities Using a High‐Throughput Version of MM‐PBSA.
Authors: Brown Scott P. , Muchmore Steven W.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Antibacterial, Antiasthmatic and Antidiabetic Activities of Novel N‐Substituted‐2‐(benzo[d]isoxazol‐3‐ylmethyl)‐1H‐benzimidazoles.
Authors: Vaidya Sanjay Dashrath , Kumar Bobba Venkata Siva , Kumar Ramanatham Vinod , Bhise Umesh Nanasaheb , Mashelkar Uday Chandrakant
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Alkylation of Azoles: Synthesis of New Heterocyclic‐Based AT1‐Non‐Peptide Angiotensin (II) Receptor Antagonists.
Authors: Al‐Azmi Amal , George Paulson , El‐Dusouqui Osman M. E.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemical Speciation of Environmentally Significant Metals with Inorganic Ligands. Part 2. The Cu2+—OH‐, Cl‐, CO32‐, SO42‐, and PO43‐ Systems (IUPAC Technical Report)
Authors: Powell Kipton J. , Brown Paul L. , Byrne Robert H. , Gajda Tamas , Hefter Glenn , Sjoberg Staffan , Wanner Hans
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Phase Diagrams of the Water‐Rich Parts of the Rare Earth Metal Chloride—Water Systems
Authors: Guminski C.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Carbon, Activated
Authors: Baker Frederick S. , Miller Charles E. , Repik Albert J. , Tolles E. Donald
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Compounds and Structures in the Solid State
Authors: Cussen Edmund J.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Spin Accumulation in Metallic Nanoparticles
Authors: Ernult F. , Yakushiji K. , Mitani S. , Takanashi K.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Solubility of Salts in Water: Key Issue for Crystal Growth and Dissolution Processes
Authors: Koutsoukos Petros G. , Kofina Aikaterini N. , Kanellopoulou Dimitra G.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Strained Metallocenophanes and Related Organometallic Rings Containing π‐Hydrocarbon Ligands and Transition‐Metal Centers
Authors: Herbert David E. , Mayer Ulrich F. J. , Manners Ian
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1‐Lithio‐1,3‐dienes: Useful Building Blocks for Cyclic Compounds
Authors: Xi Zhenfeng
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthetic Multifunctional Nanoarchitecture in Lipid Bilayers: Ion Channels, Sensors, and Photosystems
Authors: Mareda Jiri , et al. et al.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Naturally Occurring Secoiridoids and Bioactivity of Naturally Occurring Iridoids and Secoiridoids. A Review. Part 2.
Authors: Dinda Biswanath , Debnath Sudhan , Harigaya Yoshihiro
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Development of New Methods to Introduce Unnatural Functional Molecules into Native Proteins for Protein Engineering
Authors: Nakata Eiji , Tsukiji Shinya , Hamachi Itaru
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Development and Industrialization of the Vapor‐Phase Beckmann Rearrangement Process
Authors: Izumi Yoshitaka , Ichihashi Hiroshi , Shimazu Yasumoto , Kitamura Masaru , Sato Hiroshi
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthetic and Natural Steroid Dimers (1997‐2006)
Authors: Nahar L. , Sarker S. D. , Turner A. B.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Transition Metal Dendrimer Catalysts
Authors: Berger Alexsandro , Gebbink Robertus J. M. Klein , van Koten Gerard
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Faster Selective Chemistry by Microflow and Continuous Microwave Synthesis
Authors: Schwalbe Thomas , Simons Keith
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
p‐Quinomethanes
Authors: Griesbeck A. G.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
o‐Quinomethanes
Authors: Pettus T. R. R. , Selenski C.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemical Glycosylation in the Synthesis of Glycoconjugate Antitumor Vaccines
Authors: Galonic Danica P. , Gin David Y.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Substrate Trafficking and Dioxygen Activation in Bacterial Multicomponent Monooxygenases
Authors: Murray Leslie J. , Lippard Stephen J.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Road to Non‐Heme Oxoferryls and Beyond
Authors: Que Lawrence Jr.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Understanding How the Thiolate Sulfur Contributes to the Function of the Non‐Heme Iron Enzyme Superoxide Reductase
Authors: Kovacs Julie A. , Brines Lisa M.
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Development of 2,2′‐Iminodiethanol Selective Production Process Using Shape‐Selective Pentasil‐Type Zeolite Catalyst
Authors: Tsuneki Hideaki , Kirishiki Masaru , Oku Tomoharu
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Formation of Large Molecular Cluster Anions and Elucidation of Their Electronic Structures
Authors: Mitsui Masaaki , Nakajima Atsushi
Published: September 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Measured and calculated CD spectra of G‐quartets stacked with the same or opposite polarities
Authors: Gray Donald M. , Wen Jin‐Der , Gray Carla W. , Repges Rudolf , Repges Charlotte , Raabe Gerhard , Fleischhauer Jörg
Published: September 2007

Circular dichroism (CD) spectroscopy is widely used to characterize the structures of DNA G‐quadruplexes. CD bands at 200–300 nm have been empirically related to G‐quadruplexes having parallel or antiparallel sugar‐phosphate backbones. We propose that a more fundamental interpretation of the origin of the CD bands is in the stacking interactions of neighboring G‐quartets, which can have the same or opposing polarities of hydrogen bond acceptors and donors. From an empirical summation of CD spectra of the d(G)5 G‐quadruplex and of the thrombin binding aptamer that have neighboring G‐quartets with the same and opposite polarities, respectively, the spectra of aptamers selected by the Ff gene 5 protein (g5p) appear to arise from a combination of the two types of polarities of neighboring G‐quartets. The aptamer CD spectra resemble the spectrum of d(G3T4G3), in which two adjacent quartets have the same and two have opposite polarities. Quantum‐chemical spectral calculations were performed using a matrix method, based on guanine chromophores oriented as in d(G3T4G3). The calculations show that the two types of G‐quartet stacks have CD spectra with features resembling experimental spectra of the corresponding types of G‐quadruplexes. Chirality, 2008. © 2007 Wiley‐Liss, Inc.
An improved synthesis of 10,11‐didehydro Cinchona alkaloids
Authors: Kacprzak Karol M. , Lindner Wolfgang , Maier Norbert M.
Published: September 2007

A revised procedure for the conversion of the four major Cinchona alkaloids (quinine, quinidine, cinchonidine, and cinchonine) into their respective 10,11‐didehydro derivatives is described. The reported protocol offers several advantages over a recently published synthetic route. These include (i) enhanced robustness (ii) ready scalability (iii) reduced operational complexity and number of steps (iv) chromatography‐free work‐up. In addition, toxic solvents were replaced by environmentally less problematic alternatives. Chirality, 2008. © 2007 Wiley‐Liss, Inc.
Observation and characterization of a specific vibrational circular dichroism band in phenyl glycosides
Authors: Taniguchi Tohru , Tone Ikuko , Monde Kenji
Published: September 2007

Application of vibrational circular dichroism (VCD) spectroscopy to structural analysis of carbohydrates has recently progressed. However, few studies on glycoconjugates VCD have thus far been reported, despite the fact that naturally occurring carbohydrates exist as various glycoconjugates. To further explore the application of the VCD technique, we have measured a series of aromatic glycosides and found that axial aromatic glycosides exhibited a negative band at around 1230 cm−1 while equatorial ones showed flat features in this region. This is the first structure–spectra relationship on glycoconjugate VCD that distinguishes the stereochemistry of the sugar anomers. Several model compounds were prepared and their vibrational properties calculated by using the density functional theory (DFT) method, which assigned the vibrational mode of this band based on the stretching motion of the glycosidic oxygen and aromatic carbon. This concept that aglycan parts can reflect stereochemical information of sugar moieties may encourage further VCD studies on glycoconjugates to realize practical structural analysis of carbohydrates. Chirality, 2008. © 2007 Wiley‐Liss, Inc.
Development of a model with which to predict the life expectancy of patients with spinal epidural metastasis
Authors: Bartels Ronald H. M. A. , Feuth Ton , van der Maazen Richard , Verbeek André L. M. , Kappelle Arnoud C. , André Grotenhuis J. , Leer Jan Willem
Published: September 2007

BACKGROUND.

The surgical treatment of spinal epidural metastasis is evolving. To be a surgical candidate, a patient should have a life expectancy of at least 3 months. Estimation of survival by experienced specialists has proven to be unreliable.

METHODS.

The Cox proportional hazards model was used to make a prediction model. To validate the model, Efron optimism correction by bootstrapping was performed. Retrospective data of patients treated for a spinal metastasis were used. Possible predictive factors were defined based on clinical experience and the literature. Statistical methods and clinical knowledge were also used to reveal an optimal set of predictors of survival. Data from patients treated at the Department of Radiation Oncology for spinal metastasis between 1998 and 2005 were evaluated.

RESULTS.

The case notes of 219 patients form the base of this study. In the final model, only 5 variables were required to predict the survival of a patient with spinal metastasis: sex, location of the primary lesion, intentional curative treatment of the primary tumor, cervical location of the spinal metastasis, and Karnofsky performance score. Examples with different predictors are given. The R index of Nagelkerke was 0.36 (95% confidence interval [95% CI], 0.28–0.48) and the c‐index 0.72 (95% CI, 0.68–0.77).

CONCLUSIONS.

A reliable and simple model with which to predict the survival of a patient with spinal epidural metastasis is presented. Without the need for extensive investigations, survival can be predicted and only 5 easily obtainable parameters are required. Cancer 2007. © 2007 American Cancer Society.