bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of orally administered pimobendan on platelet function in healthy adult cats
Authors: Kennerly Rebecca , Coleman Amanda E. , Jasper Shanese L. , Arnold Robert D. , Brainard Benjamin M.
Published: July 2023

OBJECTIVE

Several phosphodiesterase inhibitors have demonstrable antiplatelet actions when administered to human patients. Concentration-dependent inhibition of feline platelet aggregation by pimobendan has been previously demonstrated in vitro. However, there are no published reports characterizing the effect of oral pimobendan, administered at therapeutic doses, on platelet function in cats. This study aimed to evaluate the effect of orally administered pimobendan on platelet function in healthy adult cats.

ANIMALS

6 healthy purpose-bred adult cats

METHODS

Cats were administered pimobendan orally at a dosage of 0.625 mg/cat (low-dose) twice daily for 1 week, followed by 1.25 mg/cat (high-dose) twice daily for 1 week. Venous blood sampling for platelet testing and plasma drug concentration occurred at baseline, 1 hour postdose on the eighth day of treatment with low-dose pimobendan, 1 hour postdose on the eighth day of treatment with high-dose pimobendan, and after a 1-week washout period. Platelet function was assessed by whole blood aggregometry and by use of a platelet function analyzer (PFA-100®). Friedman tests were used to compare platelet function parameters among the 4 sampling timepoints.

RESULTS

After 1 week of treatment, median (range) plasma pimobendan concentrations were 15.1 ng/mL (6.89–20.2 ng/mL) and 32.8 ng/mL (23.3–44.8 ng/mL) in cats receiving low-dose and high-dose pimobendan, respectively. No significant differences in PFA closure time or any aggregometry variable were found among the treatment conditions.

CLINICAL RELEVANCE

Pimobendan was not associated with measurable inhibition of platelet function when administered orally to healthy adult cats at 2 clinically relevant dosages.
DIGITAL BANKING SERVICES: CUSTOMERS’ PROS AND CONS. A THEORICAL LITERATURE REVIEW
Authors:   University of Sfax, Sfax, Tunisia, GARGOURI Omar
Published: July 2023

This paper is a synthesis of several theoretical works on the pros and cons of digital banking services. The objective is to allow future users of digital banking services to have a clearer idea of the pros that these services can offer. In fact, pros are many: availability, mobility, time saving, ease of access to services, autonomy in the relationship with the bank, reducing banking service prices and increasing interest rates on deposits, online bill payment, knowing about bank products, non-discrimination of technology and environment friendly. As for cons, they include: absence of human contact, complexity, fear of insecurity, no or slow internet connection, limited scope of the services offered, unnecessary letters and notifications and high using costs.
Responder e corresponder em tom menor
Authors: Nicolaiewsky Clarissa , Gonçalves Teresa
Published: July 2023

Neste artigo propomos pensar a escola como espaço público e democrático a partir de uma pesquisa de observação participante realizada em uma escola pública do Rio de Janeiro que, apelidada carinhosamente de Mariana, também assim nomeia suas trabalhadoras e trabalhadores. A construção desta comunidade Mariana é compreendida em articulação com o conceito de produção do comum como o que nos possibilita habitar o mundo e crescer com e na presença dos outros. O trabalho das Marianas nos permite pensar como esses movimentos de produção do comum se dão a partir de gestos menores capazes de realizar transgressões, produzindo, nas brechas, formas mais potentes de viver a educação. Tais questões são discutidas a partir das experiências acompanhadas, como as assembleias semanais e um projeto desenvolvido que perseguiu o cuidado de si, do outro e do planeta. É, pois, esta educação menor e seus movimentos de responder e corresponder que nos interessam.
ANALISIS KEPUTUSAN INVESTASI PADA SAHAM PERBANKAN MENGGUNAKAN CAPM DAN CAPM-MONTE CARLO
Authors: SILABAN EMERALD DIORI , DHARMAWAN KOMANG , NILAKUSMAWATI DESAK PUTU EKA
Published: July 2023

Penelitian ini bertujuan untuk menghitung nilai beta dan ekspektasi return pada CAPM dengan menggunakan data historis dan menggunakan data dari simulasi Monte Carlo. Data yang digunakan dalam penelitian ini adalah data saham dari indeks infobank15. Model yang digunakan dalam penelitian ini adalah model ekuilibrium CAPM dan untuk mengestimasi harga saham penelitian ini menggunakan simulasi Monte Carlo. Hasil penelitian menunjukkan perhitungan beta menggunakan data historis dan data simulasi saham BBCA (0,91578 dan 0,89393), BBNI (2,10434 dan 2,28636), BBRI (1,42862 dan 1,43427), BMRI (1 ,28249 dan 1,37485), dan BBTN (2,49935 dan 2,75265). Dengan hasil tersebut saham BBCA defensif karena beta kurang dari satu dan empat saham lainnya agresif karena beta lebih dari satu. Hasil perhitungan expected return dengan menggunakan data historis dan data simulasi adalah BBCA (5,42% dan 5,28%), BBNI (6,46% dan 8,05%), BBRI (5,87% dan 6,36%) , BMRI (5,74% dan 6,24%), dan BBTN (6,81% dan 8,98%).
Klasifikasi Kekuatan Struktur Beton Menggunakan Convolutional Neural Networks
Authors: Hartanto Johan , Lina
Published: July 2023

Concrete is one of the most important elements in building a building construction. Concrete is widely used because it has advantages compared to other construction materials. In addition, the development of concrete construction has increased rapidly compared to other constructions, especially in the way of making concrete to the technology and use of materials used. In its development, materials will increase so that experiments in the laboratory make the costs swell. Therefore, a research is proposed which is intended to help researchers as well as to provide a comparison of the use of the model used.

The method used to classify will use the CNN model by producing output that will display the class categories on the variables that have been inputted. The test results on training data resulted in an accuracy of 86.04% and testing on test or validation data was 82.14% on the Adam optimizer and 83.25% on training data and 80.35% on test or validation data on RMSprop. After determining the model to be used, it is continued with the use of K-fold validation.
APLIKASI PREDIKSI NILAI DAN REKOMENDASI MATAKULIAH MENGGUNAKAN METODE COLLABORATIVE FILTERING DAN ALGORITMA C4.5 PADA PROGRAM STUDI TEKNIK INFORMATIKA UNIVERSITAS X
Authors: Filbert  , Mulyawan Bagus , Sutrisno Tri
Published: July 2023

A common problem with lectures and colleges is that students have difficulty choosing a course due to the large number of choices, or the student credits are limited  due to poor course results. We hope that by designing this value prediction application and course recommendations, we will help students  get the best course recommendations according to their abilities and grades. The program uses the C45 algorithm to display the selection of courses with  the lowest score, and the scores generated by collaborative filtering calculations are advanced by determining the value of similarity between students and predicting grades. The system will identify each course with the highest average score / highest pass rate and it will be used as a student course recommendation. Test results show that the accuracy in determining a student's recommended course using the C45 algorithm is 70%, and the calculation  error in determining a student's value prediction is 40-56%.
WEBSITE REKOMENDASI DAN KLASIFIKASI LAGU MENGGUNAKAN METODE WEIGHTED K-NEAREST NEIGHBOR
Authors: Harto Caroline Wili , Mawardi Viny Christanti , Perdana Novario Jaya
Published: July 2023

As the years went by, music has become one of the most evolving aspects of human history. There is a load of musical development around the globe, especially in music genres. Due to these differences and developments, a design was created to be able to make song recommendations according to the genre types and classifications of music or song. The data that is processed as training data is in the form of song metadata with various music features sourced from Spotify. Song recommendations are performed using the Euclidean Distance calculation between musical features or songs, while song classification is carried out using the Weighted K-Nearest Neighbor (WKNN) method calculation through audio wave type file analysis which then takes the musical features and calculates them based on the existing song or music data. The end result of this process is the genre class label. There is also a classification evaluation calculation using a confusion matrix. With the design of this system, it is hoped that the user will be able to search for song recommendations that have similarities to the song chosen by the user and classify genres according to the user's input song.
PERANCANGAN APLIKASI TATA KELOLA KEUANGAN SALON YINHOA BERBASIS WEB
Authors: Marzelino Kevin
Published: July 2023

Prior to the creation of this web-based financial management application, Salon Yinhoa ​​carried out all financial processes using the traditional method with on-the-spot transaction processes and recording was done manually using an excel file. As customers increase, recording transactions is considered to be quite time-consuming and a solution is needed to simplify financial management. Therefore, it is necessary to design a web-based financial management application for Salon Yinhao as a database for financial management using the SDLC-waterfall method. The final result is that the web-based application is used to facilitate financial management at Salon Yinhoa.
SISTEM INFORMASI E-REKRUTMEN BERBASIS WEB PADA PT PHAROS INDONESIA
Authors: Fernandi Renaldi , Dewayani Ery
Published: July 2023

Human resources are individuals who work productively for an organization such as an institution or company in an effort to achieve organizational goals that act as a driver and have value as assets for the organization so that their capabilities need to be improved and developed. Considering that human resources have a very large contribution to the company in achieving its goals and are an important capital asset for the company, therefore, a web-based e-recruitment information system in the process of recruiting and selecting prospective workers is needed by PT Pharos Indonesia to obtain qualified and competent human resources. 

The development of this e-recruitment information system uses the Waterfall System Development Life Cycle (SDLC) methodology. The database used by this application uses the MySQL database. The programming languages used are Golang and Javascript with the ReactJS Framework. Web-based e-recruitment information system can improve the recruitment process at PT Pharos Indonesia. Processing prospective employee data becomes easier, faster, and more accurate because prospective employee data is processed by computerization
Workshop Augmented Reality Dengan Vuforia Untuk Sma Sinar Dharma
Authors: Haris Darius Andana , Wirawan Jason , Sanjaya Steven
Published: July 2023

Kemajuan teknologi informasi dan komunikasi telah menjadi faktor penting yang bermanfaat dalam berbagai aspek. Segala hal yang dilakukan secara online juga mendorong kemajuan di bidang teknologi informasi dan komunikasi. Salah satu bentuk produk dari teknologi informasi dan komunikasi adalah video game. Dengan perkembangan dan popularitas video game yang pesat, ini mendukung banyak jurusan permainan di perguruan tinggi. Pada tingkat sekolah menengah atas, pembelajaran video game dapat dilakukan melalui kegiatan workshop. Dengan kegiatan workshop ini, siswa sekolah menengah atas dapat mengembangkan potensi mereka lebih awal dan membuat pembelajaran yang mereka dapatkan sebagai persiapan untuk memasuki dunia perguruan tinggi nantinya terutama dalam konten Augmented Reality. Kegiatan workshop ini juga menjadi salah satu cara bagi siswa untuk mendukung peningkatan prestasi non-akademik.
Vigilância e epidemiologia de infecções hospitalares causadas por Staphylococcus aureus em um hospital Universitário na cidade de Uberlândia-MG
Authors: Pereira Ana Laura Cunha , De Oliveira Samantha Neves , Silva Helisângela de Almeida
Published: July 2023

As infecções relacionadas à assistência à saúde são aquelas adquiridas durante o período de permanência dos pacientes em unidades de saúde. Este trabalho avaliou infecções causadas por Staphylococcus aureus no Hospital de Clínica da Universidade Federal de Uberlândia. O estudo foi uma investigação longitudinal e prospectiva,  no período de novembro/2015 a outubro/2016, onde as amostras estudadas foram identificadas pelo laboratório de Microbiologia do HC-UFU utilizando o sistema automatizado VITEK®2. Foram isolados 62 amostras de S. aureus, sendo 29 MRSA e 33 MSSA. A principal síndrome infecciosa encontrada foi a infecção de corrente sanguínea seguida de infecções de sítio cirúrgico. As unidades de UTI (neonatal, pediátrica, adulta) foram as que mais apresentaram infecções por S. aureus e posteriormente a clínica médica.  De acordo com o perfil de resistência, 29 pacientes eram resistentes a Oxacilina, 54 a Benzilpenicelina e nenhuma a Vancomicina. Com base nestes  dados salientamos a importância de estudos como este para monitorar os índices de resistência nos hospitais. Palavras chave: IRAS, MRSA, MSSA, Resistência bacteriana.
A capacidade para o trabalho de professores do ensino superior e seus fatores associados: um levantamento em uma instituição de ensino privada
Authors: Piratelli Rodrigo Luiz Baptista , Garcia Hermosilla José Luis , Achcar Jorge Alberto
Published: July 2023

Pesquisas com a finalidade de identificar a capacidade de trabalho dos indivíduos são de grande importância para as organizações, uma vez que concorrem para a manutenção e promoção da capacidade para o trabalho, trazendo benefícios não só para o indivíduo, mas também para a sociedade. O Índice de Capacidade para o Trabalho (ICT), tradução literal do questionário Work Ability Index (WAI), é um instrumento que visa captar a autoavaliação do indivíduo sobre sua capacidade para realizar o trabalho no presente e no futuro próximo, levando em consideração a sua função frente às exigências laborais, de saúde e recursos psicológicos. O presente projeto de pesquisa tem como objetivo mensurar o Índice de Capacidade para o Trabalho dos docentes do ensino superior de uma instituição de ensino do interior do estado de São Paulo e levantar seus fatores associados. Para isso, será realizada uma modelagem estatística no software Minitab que tomará como base técnicas de regressão linear múltipla, com base na análise descritiva dos dados, para verificar a existência ou não de fatores associados entre as variáveis pesquisadas (idade, gênero, campo do conhecimento, curso em que leciona etc.).  Segundo alguns relatos científicos, há uma relação inversa entre a idade e a capacidade para o trabalho (uma tendência à baixa capacidade para o trabalho em indivíduos mais velhos). Com esta pesquisa, espera-se que docentes que lecionam em determinadas áreas tenham um decréscimo mais acentuado no valor do ICT do que outros, assim como docentes que exercem outras atividades laborais em paralelo à docência, e que essa variação possivelmente também esteja relacionada à idade do funcionário e ao tempo de atividade.
Psicologia social e HIV/AIDS: um estudo de revisão
Authors: Acuna José Tadeu , Favorido Sant’Ana Mariana , Mendes Rocha Isabela , Cursino Lanfranchi Ariela
Published: July 2023

Objetivou-se conhecer e analisar as investigações nacionais brasileiras que abordam o fenômeno do Vírus da Imunodeficiência e da Síndrome da Imunodeficiência Adquirida (HIV/AIDS) a partir da psicologia em sua abordagem social. Neste sentido, delineou-se um estudo qualitativo de revisão de artigos datados nos últimos 11 anos e seis meses, sendo o lócus de pesquisa o Portal de Periódicos da CAPES e a técnica de análise qualitativa de conteúdo como procedimento organizador e analítico. Os nove artigos analisados apresentaram contribuições ao campo da psicologia, no tocante ao entendimento de como o HIV/AIDS é representado tanto na perspectiva da pessoa soropositiva quanto na de terceiros. Foi discutido que no Brasil a psicologia em uma perspectiva social se encontra numa etapa de diagnóstico e de análise do fenômeno HIV/AIDS, a qual produz conhecimentos necessários para futuras intervenções. Entretanto, destacou-se que é preciso avançar na produção de medidas propositivas no que tange à superação dos desafios vivenciados pelo sujeito soropositivo.
Reflexões sobre o alcance do direito ao silêncio e não autoincriminação
Authors: Perez Filho Augusto Martinez , Riul Naves Raul , Martinez Perez Augusto
Published: July 2023

O presente artigo tem por objetivo análise crítica e valorativa acerca do estudo científico sobre a relação e confronto de limites dos direitos e garantias constitucionalmente previstos tangentes ao Direito processual e material penal, quais sejam: o direito ao silêncio e a não autoincriminação, com o crime de perjúrio. Denota-se, a princípio, que legislação brasileira não prevê como prática punível o crime de perjúrio, apesar de já arquivado projeto de lei no sentido de sua criação. Tendo isso em vista, veja-se que durante o processamento de ações penais nos termos das normas pátrias, visando-se a proteção do in dubio pro reo, bem como a garantia de não autoincriminação, o acusado não é obrigado, assim como as testemunhas, a prestar compromisso de verdade para com os fatos narrados, bem como, a ele também se reserva o direito ao silêncio sem prejuízo algum. Trata-se de pesquisa bibliográfica, utilizando-se de dados através de análise de doutrinas, leis e artigos científicos nacionais e internacionais. Dessa forma, buscou analisar o efetivo alcance do direito ao silêncio na esfera penal, comparando-se tais limites também, entre a garantia de não autoincriminação e a literatura estrangeira sobre o crime de perjúrio.
The Plight of the Oromo Refugees in the Horn of Africa
Authors: Abdi Taha , Harrell-Bond Barbara E.
Published: July 2023

The History of the Oromo people of Ethiopia is one of colonization, subjugation and decimation. In fact, the first refugees on record in the Horn were Oromos who left their homeland during the early period of Ethiopian occupation. Annexation by Ethiopia meant the loss of their main source of livelihood, the land, and the denial of the most basic human and national rights. The situation prompted frequent armed uprisings, which have become more organized in recent years. Confilict, political persecution, and the inept and destructive policies of the Ethiopian government have now displaced hundreds of thousands of Oromos. These people live either in the safe area within the Oromos' region, occupied by the Oromo Liberation Front (OLF), or in the neighbouring states of Somalia, Djibouti, Kenya, the Sudan and beyond.
The Displaced People of Mozambique
Authors: Cammack Diana
Published: July 2023

The crisis in Mozambique which has recently captured the world's atention is the result of a number of factors, some of long duration. Mozambique, a country abouth half again as big as California with a population of about fourteen million and a GNP per capita (1984) of US $210, was left by its Portuguese masters with only US $1 million in foreign reserves and gold an annual GNP per capita of not much more than US $100 and a population with an. illiteracy rate approaching 98% and largely unskilled. All but 15.000 colonialists fled,many to South Afiica, and in their bitterness they destroyed and paralyzed machinery. As they left they often simply removed a vital mechanical part, other times they destroyed repair manuals and business records in an effort to sabotage the Mozambican economy.
MODEL PENGELOLAAN SUMBERDAYA WILAYAH PESISIR PROVINSI KALIMANTAN UTARA BERBASIS MASYARAKAT DAN BERKELANJUTAN
Authors: Basri
Published: July 2023

What is very important in the sustainable management of coastal marine areas is the involvement of local communities from planning to implementation. This study aims to explain that community-based and sustainable management of coastal marine areas in North Kalimantan is the most ideal coastal management model. This type of research is the normative legal research method with qualitative analysis. The results showed the benefits of community-based and sustainable management of the coastal marine area of ​​North Kalimantan in improving the welfare of coastal communities because it is based on the potential and characteristics of the coastal marine area. Thus, community-based and sustainable management of the coastal marine area of ​​North Kalimantan is a model of coastal area management that favors coastal communities.

Keywords; Coastal areas, Indigenous based, sustainable
KEWENANGAN PENYELESIAN SENGKETA KONSUMEN PERJANJIAN KREDIT MOTOR DALAM PERPEKTIF HUKUM
Authors: Suyikati
Published: July 2023

The issue of forced motorcycle withdrawals by leasing companies is of particular concern to regulations that have not yet provided a solution to these problems, considering that the application of standard agreements has its own weaknesses, consumer issues handled by BPSK regarding motorcycle withdrawals by leasing parties, resulting in consumers losing control over motorcycles but BPSK does not have a big role in carrying out legal actions and its authority is still limited and its decisions still do not have executorial legal force, seeing this many phenomena the Constitutional Court issued Constitutional Court Decision No.18/PUU-XVII/2019 this decision gives a lot perceptions about the procedure for withdrawing vehicles that are fiduciary guarantees, one of which is the right to execute through the courts, but execution without trial is allowed on the condition that the debtor acknowledges a default. This means that the Court only examines article 15 paragraph 2 while the Obj The guarantee certificate has actually been transferred unilaterally, meaning that it is legal for the creditor to make a withdrawal with reference to the contents of the main agreement between the creditor and the debtor and article 1338 of the Civil Code.

Keywords: Authority. Dispute, motorbikes, Law
KEPASTIAN HUKUM PENETAPAN LOKASI PENGADAAN TANAH BAGI PEMBANGUNAN BENDUNGAN BENER DI PURWOREJO
Authors: Tandiono Sudargo , Lestari Mega , Arwanto Bambang
Published: July 2023

Cases of corruption that occur in the natural resource sector can be realized because of some irregularities committed by officials who have authority in the natural resources sector itself related to the issuance of state administrative decisions, so that these actions do not harm the state in terms of finances but also have a negative impact on other humans and ecosystem integrity. The purpose of this research is to find out about the discrepancy between the Bener dam construction decisions and the findings found and how to prevent corruption in the natural resources sector in Indonesia.

Keywords: Dam, Corruption, Decisions
Overview of System Identification Tool Advancements at Systems Technology, Incorporated
Authors: Lampton Amanda K. , Klyde David H. , Schulze P. Chase
Published: July 2023

For nearly two decades, Systems Technology, Inc. has been investigating novel system identification methods and practical applications. Two such methods will be highlighted herein: 1) the use of wavelet-based scalograms to explore the nature of dynamic systems in both the time and frequency domains simultaneously; and 2) a method to estimate frequency, damping, and mode shapes for lightly damped aeroelastic modes exhibited across a variety of air vehicles. From past work, two scalogram-based metrics have evolved, which are the power frequency and inceptor peak power phase, that will be one focus of this paper. The power frequency provides a metric that considers not only the dominant frequencies of the signal of interest, such as the command input from a pilot, but also the power at those frequencies. For the inceptor peak power phase, scalograms are used to identify the peak input power of a pilot’s inceptor command signal that when compared against a pitch or roll rate phase angle at the peak frequency produces a new method to detect the onset of pilot-induced oscillations. This paper will further describe system identification tools that extract modal information of aeroelastic vibrations observed in flight. Because it is often difficult to obtain input excitation data, particularly in real time, Systems Technology, Inc. developed a modal identification software toolbox that provides an innovative approach based on curve-fitting frequency domain decomposition, which relies only on output sensor data to identify the aeroelastic modes. Flight-test data are used to demonstrate the effectiveness and efficacy of the system identification approaches.
A Community-based Survey on Stroke Awareness in Underprivileged Urban Areas of Bangalore, India
Authors: Baby Priya , Kundayi Ramya , Kathyayani B.V.
Published: July 2023

Stroke is a major public health problem all over the globe, especially in low and middle-income countries like India. In the urban areas of India, the disease has grown to epidemic proportions. The underprivileged residents in urban slum areas have poor health literacy, usually resulting in poor health-seeking behaviours. Hence, efforts towards stroke prevention and risk factor control are critical in urban slum areas. The objective of the study was to assess the awareness about stroke among adults residing in the urban slum area of Bangalore, India. A cross-sectional survey was conducted using a mixed-methods approach, where data were collected from 490 adults using self-reported questionnaires. Over half of the participants (52%) did not know that the brain is the primary organ affected by stroke. Hypertension (44.9%) and diabetes mellitus (23.6%) were the most cited risk factors by participants. In binary logistic regression analysis, higher education was a predictor of stroke awareness (OR 0.65, p=0.02). Several misconceptions about stroke risk factors were identified among the participants. Poor awareness about stroke and its risk factors among the underprivileged urban population is demonstrated in this study. The study highlights the need to develop and implement strategies and programmes to improve awareness about stroke for the whole community.
Hematuria in a young severe hemophilia patient – A case report on a rare radiological finding
Authors: Roy Shipla , Ghosh Kaustav , Mandal Prakas Kumar
Published: July 2023

Renal ectopia or ectopic kidney is one of the common renal anomalies in which there is faulty migration of the fetal pelvis during the embryonic period. Hemophilia is an inherited coagulation disorder characterized by recurrent and spontaneous bleeding due to a deficiency of clotting factor VIII or IX. Clotting factor concentrates are used as standard therapy for the management of bleeding episodes. Hematuria is the presence of blood in urine that is either visible to the naked eye (macroscopic) or nonvisible (microscopic). Common etiologies of hematuria include congenital anomalies, calculus, inflammation, and infectious and malignancy of the renal and urogenital tract. Here, we present a 14-year-old male with severe hemophilia A who presented with severe pain abdomen and hematuria. On evaluation, he was found to have a left-sided ectopic kidney. In addition to the overdue discovery of the left-sided ectopic kidney, there is the coexistence of a bleeding disorder which may pose a challenge in the patient’s management.
IT-Assisted Optimisation of Fuel Consumption in Air Transport
Authors: Walter Andreas
Published: July 2023

Die Luftfahrt ist nach wie vor ein wichtiges Transportmittelfür Passagiere und Fracht. Im Jahr 2022 war Europa wiederauf etwa 85 % des Niveaus von 2019 gestiegen. Allerdings sind TreibstoffTreibstoffeinsparung und Emissionsreduzierung habenin den letzten Jahren immer wichtiger geworden.Im Rahmen einer Doktorarbeit wurden Möglichkeiten zur Reduzierung des KraftstoffKraftstoffverbrauchs durch Verringerung der Kraftstoffreserveuntersucht. Das Hauptaugenmerk dieses Papiers liegt auf den Chancen und Herausforderungen, diedie sich mit der Einführung neuer Treibstoffvorschriften in dereuropäischen Luftfahrtvorschriften. Betreiber miteinem angemessenen Sicherheitsniveau können maßgeschneiderteBestimmungen anwenden. Dies erfordert den Nachweis des Sicherheitsniveausniveaus. Dies wird durch die Festlegung spezifischer SicherheitsLeistungsindikatoren (SPI), deren Einhaltungdann während des Betriebs kontinuierlich überwacht und bewertetBetrieb. Dies erfordert die Sammlung und Auswertung vonentsprechend großer Datenmengen. Dies ist nurnur mit entsprechenden IT-Anwendungen möglich. Andererseits ermöglichen leistungsbezogene Regelungeneine individuellere Umsetzung auf und durch diejeweiligen Unternehmen durch den Nachweis eines entsprechendenentsprechenden Sicherheitsniveaus. Dazu werden Sicherheitsindikatoren verwendetverwendet, die aus verschiedenen vorhandenen Daten gewonnen undaus verschiedenen vorhandenen Daten gewonnen und ausgewertet werden müssen. Eine große Menge an Daten,die nur mit Hilfe verschiedener IT-Anwendungen gesammelt und verarbeitet werden könnenIT-Anwendungen gesammelt und verarbeitet werden können, stellt eine Herausforderung dar.Unternehmen können jedoch von denentsprechende Vorteile, wenn sie diese bewältigen können.
PENERAPAN MEDIA PEMBELAJARAN MENGGUNAKAN PhET SIMULATION UNTUK MENINGKATKAN HASIL BELAJAR PESERTA DIDIK PADA MATERI HUKUM NEWTON DI SMP NEGERI 23 PONTIANAK
Authors: Muna Arif Khasanul , Tandililing Edy , Oktavianty Erwina
Published: July 2023

Penelitian ini bertujuan untuk mengetahui: 1) Adakah perbedaan hasil belajar dari kelas treatmen dan kelas kontrol 2) Berapa besar efektivitas penerapan media pembelajaran PhET simulation, 3) Berapa besar minat belajar setelah diterapkannya media pembelajaran PhET simulation dalam meningkatkan hasil belajar pada materi hukum Newton. Penelitian ini dilaksanakan pada tanggal 01 November 2021 hingga pada tanggal 18 November 2021 di SMP Negeri 23 Pontianak yang beralamat di Letdjen Supratman, kecamatan Pontianak, Kota Pontianak. Penelitian ini mengambil 2 kelas yaitu kelas VIII E sebagai kelas perlakuan (treatmean) dengan jumlah siswa 30 orangpeserta didik dan kelas VIII H sebagai kelas Kontrol dengan jumlah peserta didik 28 peserta didik. Berdasarkan hasil belajar kelas treatmen dan kelas kontrol memiliki hasil yang signifikan, begitu pula didukung hasil perhitungan N-Gain dimana mendapat nilai persentase sebesar 63,12% pada kelas treatmen, sedangkan pada kelas kontrol dengan nilai N-Gain sebesar 45,88%. Sedangkan pada hasil perhitungan respon peserta didik mendapat nilai rata-rata sebesar 84,50%. Sehingga merujuk dari kriteria respon peserta didik nilai rata-rata tersebut dikategorikan sangat positif dan dapat disimpulkan bahwa dari nilai rata-rata tersebut dinyatakan pembelajaran menggunakan PhET simulation memliki respon minat belajar peserta didik yang sangat tinggi.
Systematic handling of environmental fate data for model development – illustrated for the case of biodegradation half-life data
Authors: Hafner Jasmin , Fenner Kathrin , Scheidegger Andreas
Published: July 2023

Environmental hazard endpoints describing persistence, mobility, toxicity, or bioaccumulation of chemicals are often associated with high variability in experimental outcomes. The assessment of persistence in the environment is particularly affected due to a multitude of influencing environmental factors, including the taxonomic composition and physiological state of the microbial community present. Biotransformation experiments may therefore result in half-lives spanning several orders of magnitude for the same substance tested with different environmental samples. Due to experimental limitations, values may further be beyond the limits of reliable half-life quantification (i.e., censored data points), and the number of data points per substance may vary considerably. However, reliable data describing average half-lives and their natural variability are an important foundation for building predictive models for environmental hazard endpoints, which are urgently needed by regulatory authorities to manage existing chemicals and by industry for the design of benign, non-persistent chemicals. Here, we propose the application of Bayesian inference to characterize the uncertainty of reported half-lives and to include censored data points to maximize the information extracted from experimental data. Our model estimates the true mean and standard deviation from a set of reported half-lives experimentally obtained for a single substance. Including censored data increases the available data volume, and reporting uncertainties helps estimating the reliability of the half-life data. We apply the inference model to 893 substances with experimental soil half-lives of varying data quantity and quality, and we estimate the true half-life distribution for each compound. Our approach can be easily adapted and applied to other environmental hazard endpoints to estimate uncertainty and to improve data quality for model development.
Electrochemistry at the edge of a van der Waals heterostructure
Authors: Plačkić Aleksandra , Neubert Tilmann J , Patel Kishan , Kuhl Michel , Watanabe Kenji , Taniguchi Takashi , Zurutuza Amaia , Sordan Roman , Balasubramanian Kannan
Published: July 2023

Artificial van der Waals heterostructures, obtained by stacking layered two-dimensional materials, represent a novel material platform for investigating physicochemical phenomena and applications. Here, the electrochemistry at the one-dimensional edge of a graphene sheet, which is sandwiched between two hexagonal boron nitride (hBN) multilayer flakes, is reported. When such an hBN/graphene/hBN heterostructure is immersed in a solution, the basal plane of graphene is protected and isolated by the hBN stack, and the edge of the graphene sheet is exclusively available in the solution. This forms an electrochemical nanoelectrode, which enabled the investigation of electron transfer using several redox probes, e.g., ferrocene(di)methanol, hexaammineruthenium, methylene blue, dopamine and ferrocyanide. The relatively low capacitance of the van der Waals edge electrode facilitates cyclic voltammetry at very high scan rates (up to 1000 V/s). Using fast scan cyclic voltammetry imaging, redox species could be detected voltammetrically down to micromolar concentrations with sub-second time resolution at the sandwiched graphene edge, promoted by the rapid equilibration of analyte species in the diffusion layer. Furthermore, the nanoband nature of the edge electrode allows its operation directly in water in the absence of added electrolyte. Finally, two adjacent edge electrodes could be realized in a redox-cycling format. In all, the van der Waals edge electrode is unique among nanoelectrodes as it enables investigations of all the above-mentioned phenomena in the same device. Due to its versatility, it constitutes a new avenue for nanoscale electrochemistry, which will be useful for studying electron transfer mechanisms as well as for the detection of analyte species in ultralow sample volumes.
Photorearrangement of Bishypersilyl-1,2-dione: The Wavelength Matters
Authors: Glotz Gabriel , Drusgala Manfred , Hamm Florian , Fischer Roland , Došlić Nađa , Kelterer Anne-Marie , Gescheidt Georg , Haas Michael
Published: July 2023

We report on the synthesis, isolation and unique photoreactivity of a novel symmetric bissilyl-1,2-dione, 3. Its UV/Vis spectrum reveals two remarkable well-separated n→π* absorption bands at λmax = 637 nm (ε = 140 Lmol-1cm-1) and 317 nm (ε = 2460 Lmol-1cm-1). Irradiation at λ = 360/365 nm affords an isolable siloxyketene 4, whereas irradiation at λ = 590-630 nm leads to selective formation of siloxirane 5 by a 1,4-trimethylsilyl migration in high yield. These remarkable wavelength-dependent rearrangements are based on characteristic photochemical reaction pathways. Irradiation at 360/365 nm populates a second excited singlet state (S2) which triggers a hitherto unknown 1,3-hypersilyl migration yielding 4. At longer wavelengths (590/630 nm), the populated first excited singlet state (S1) undergoes intersystem crossing (ISC), and 5 emerges from a triplet (T1) precursor. We have established this reaction mechanism by spectroscopy (optical, in-situ IR, and NMR) and theoretical calculations. NMR and X-ray crystallography reveal the structural features of the products.
Homo- and Hetero-Recyclable Polyesters with High Refractive Index from CO2, 1,3-Butadiene and Thiols
Authors: Zhang Zhuorui , Shen Ting , Chen Kaihao , Zeng Junjie , Ling Jun , Ni Xufeng
Published: July 2023

α-Ethylidene-δ-vinyl-δ-valerolactone (EVL) is the only intermediate to synthesize copolymers of CO2 with 1,3-butadiene whose ring-opening polymerization (ROP), however, is obstructed by the tiglate group. The saturation of the conjugated double bond is essential to the living ROP of EVL, while previous reports involve irreversible hydrogenation. In the contribution, EVL derivatives are synthesized through Michael addition reaction to saturate the conjugated double bond as well as introduce various groups to synthesize polyesters with tunable glass-transition temperatures (Tg) from -45 °C to 3 °C and excellent refractive index between 1.64 and 1.85. Living and controlled polymerizations lead to polyesters with designable number average molecular weights (Mn = 6.9-12.8 kg∙mol-1) and narrow dispersities (Đ = 1.08-1.19). The obtained polyesters are able to be recycled to the corresponding monomers which can prepare comparable polymers with identical side groups, realizing the homo-recycling. The monomers are capable of being recycled to EVL and thiols through retro-Michael addition reaction, and then the recycled EVL can be re-functionalized to generate a new monomer which produces a polyester with another side group, fulfilling the hetero-recycling. We propose an “addition-elimination-re-addition” strategy for EVL derivatives and the corresponding polyesters.
MORTGAGE DEVELOPMENT IN RUSSIA
Authors: Шибаршина О.Ю.
Published: July 2023

Цель статьи - анализ динамики развития ипотечного кредитования в России и характеристика ипотечных кредитов в РФ. Научная новизна исследования состоит в изучении современных тенденций и особенностей развития данного вида банковской сделки с целью получения дальнейшей возможности совершенствования ее механизмов. Показана динамика ставок ипотечного кредитования, динамика средневзвешенного срока ипотечного кредитования в России. Рассмотрена средняя стоимость жилья в России на первичном и вторичном рынке. На основе проведенного исследования сформулирован вывод о том, что в настоящее время является актуальным вопрос о запуске льготной ипотеки на вторичное жильё, что связано с перенастройкой финансовых потоков, вызванных переориентированием экономики страны под сегодняшние реалии.

This scientific article analyzes the dynamics of mortgage lending in Russia, presents the characteristics of mortgage loans in the Russian Federation. The dynamics of mortgage lending rates, the dynamics of the weighted average term of mortgage lending in Russia are shown. The average cost of housing in Russia in the primary and secondary market has been studied. Based on the conducted research, the conclusion is formulated that at present the issue of launching preferential mortgages for secondary housing is urgent, which is associated with the reconfiguration of financial flows caused by the reorientation of the country's economy to today's realities.
ENVIRONMENTAL FACTORS ANALYSIS DURING ORGANIZATIONAL CHANGES UNDER TURBULENCE CONDITIONS
Authors: Божко Л.М.
Published: July 2023

В условиях повышенной нестабильности внешнего окружения возникает проблема его своевременной и точной оценки для предотвращения негативного влияния, избежания рисковых ситуаций, обеспечения реализации или корректировки принятой стратегии, инвестиционных и инновационных планов, разработки мер ответного реагирования путем проведения организационных изменений. Целью исследования является разработка методики проведения анализа факторов внешней среды, позволяющей сократить период от сбора данных об окружении до принятия управленческих решений по поводу стратегии и организационных изменений, своевременно и регулярно получать достоверные и достаточные для принятия решения сведения. Определена цель анализа факторов внешней среды в управлении изменениями; сформулированы принципы анализа внешней среды; предложена методика проведения анализа факторов внешней среды, позволяющая обеспечивать руководство информацией об окружении в период повышенной нестабильности. Проведен обзор методов ситуационного анализа, позволяющих оценить внешнюю среду. Научная новизна представлена доработанной автором для условий повышенной турбулентности окружения методика PEST-анализа, который получил развитие за счет включения факторов микросреды. Результаты исследования могут использоваться в организациях для оценки внешней среды при планировании организационных изменений, для совершенствования стратегии.

In the context of increased instability of the external environment, there is a problem of its timely and accurate assessment to prevent negative impact, avoid risk situations, ensure the implementation or adjustment of the adopted strategy, investment and innovative plans and develop response measures through organizational changes. The purpose of the study is developing a methodology for analyzing environmental factors, which allows to reduce the period from collecting environmental data to making management decisions about strategy and organizational changes, to receive reliable and sufficient information for making a decision in a timely and regular manner. The article defines the purpose of the analysis of environmental factors at change management, formulates the principles of environmental analysis, proposes a methodology for analyzing environmental factors that allows to manage information about the environment during a period of increased instability. A review of situational analysis methods is conducted to assess the external environment. The author finalized the PEST analysis method for the conditions of increased environmental turbulence, which was developed by including microenvironment factors. The results of the study can be used in organizations to assess the external environment when planning organizational changes, to improve the strategy.
THE QUALITY MANAGEMENT DIAGNOSTICS OF SOCIO-ECONOMIC AND SCIENTIFIC PROCESSES IN THE RUSSIAN FEDERATION AND SUBSTANTIATION OF THE SPECIFICS OF POST-CRISIS RESULTS
Authors: Фраймович Д.Ю. , Мищенко З.В. , Гундорова М.А.
Published: July 2023

В статье выполнена диагностика воздействия карантинных ограничений на результаты социально-экономических и научных процессов в регионах РФ. Цель работы – определение отклонений в развитии территорий ЦФО на основе изучения индивидуальной динамики каждого из совокупности важнейших показателей. Научная новизна работы состоит в выявлении длительных хозяйственных, демографических и инновационных трендов и трансформаций, а также обосновании качества управленческих воздействий на соответствующие процессы.

The article analyzes the impact of quarantine restrictions on the results of socio-economic and scientific processes in the regions of the Russian Federation. The purpose of the work is to determine deviations in the development of the territories of the Central Federal District based on the study of the individual dynamics of each of the totality of the most important indicators. The scientific novelty of the work consists in identifying long-term economic, demographic and innovative trends and transformations, as well as substantiating the quality of managerial influences on the relevant processes.
TERRITORY MARKETING AS A TOOL FOR THE FORMATION OF A TERRITORIAL CLUSTER
Authors: Швайка О.И.
Published: July 2023

Актуальность исследования заключается в том, что современное экономическое развитие имеет множество очевидных тенденций, а именно: регионализация и глобализация. Реализация кластерной политики является существенным условием эффективного развития территории, что ведет к повышению конкурентоспособности региона. Целью исследования является изучение особенностей маркетинга территории как инструмента формирования территориального кластера. Автором были проведены: систематизация проблем маркетингового продвижения кластерного образования с целью разработки комплекса мероприятий для его формирования; структурирование нормативноправовой базы в сфере маркетинга территории и кластерной политики; разработка новой концепции, способной объединить цели и задачи маркетинга территории и маркетинговую политику кластерного образования.

The relevance of the research lies in the fact that modern economic development has many obvious trends, namely: regionalization and globalization. The implementation of cluster policy is an essential condition for the effective development of the territory, which leads to an increase in the competitiveness of the region. The purpose of the study is to study the features of territory marketing as a tool for the formation of a territorial cluster. The author systematized the problems of marketing promotion of cluster education in order to develop a set of measures for the formation of cluster education; structuring the regulatory framework in the field of territory marketing and cluster policy; developing a new concept that can combine the goals and objectives of territory marketing and the marketing policy of cluster education.
LOW-INCOME AND POVERTY AS NEGATIVE FACTORS AFFECTING RUSSIA'S ECONOMIC SECURITY
Authors: Розова С.В. , Дюжилова О.М. , Толстова И.А.
Published: July 2023

Цель обзорной статьи – определить значимость фактора бедности населения для экономической безопасности государства. Задачи исследования: на основе уточнения понятия «бедность» рассмотреть критерии оценки «бедности» и «нищеты», оценить масштабы явления, выявить необходимость и значимость поддержки населения в целях повышения экономической безопасности страны. Малообеспеченность, бедность и крайняя степень бедности – нищета – являются общемировой проблемой для обеспечения экономической безопасности страны. Данные негативные проявления присущи в том числе государствам, проводившим многолетнюю эффективную экономико-социальную политику. Элементы научной новизны состоят в выявлении недостатков формирования потребительской корзины, в обосновании необходимости изменения методики определения прожиточного минимума и минимальной заработной платы. При расширении зоны бедности снижается ВВП на душу населения, часть граждан страны переходят в зону нищеты, растут расходы государства на социальные программы, эффективность которых остаётся под сомнением. Результаты исследования могут быть использованы в целях разработки мер государственной поддержки малоимущих и разработки государственных программ борьбы с бедностью.

The purpose of the review article is to determine the significance of the poverty factor for the economic security of the state. Research objectives: on the basis of clarifying the concept of "poverty", consider the criteria for assessing "poverty" and "poverty", assess the scale of the phenomenon, identify the need and importance of supporting the population in order to increase the economic security of the country. Low income, poverty and extreme poverty - poverty - are a global problem for ensuring the economic security of the country. These negative manifestations are also inherent in states that have pursued many years of effective economic and social policy. The elements of scientific novelty consist in identifying the shortcomings in the formation of the consumer basket, in substantiating the need to change the methodology for determining the subsistence minimum and the minimum wage. With the expansion of the poverty zone, GDP per capita decreases, some of the country's citizens move into the poverty zone, government spending on social programs increases, the effectiveness of which remains in doubt. The results of the study can be used to develop measures of state support for the poor and the development of state programs to combat poverty.