bluuebunny/crossref_metadata_2025 huggingface dataset:
GC–MS Analysis and Fabrication of Nanoparticles of Buchanania lanzan oil for the Anticancer activity
Authors: Dahiya Mini , Yadav Monu , Kumar Sumit , Chauhan Shilpi , Lamba Deepak
Published: December 2024

This paper aims to study the phytochemical analysis of Buchanania lanzan oil and the anticancer property of its PEG-coated chitosan nanoformulation. The GC-MS analysis of Buchanania lanzan oil showed 24 compounds. In literature, pharmacology active compounds like β –sitosterol, stigmasterol, sitosterol, fucosterol, campesterol, stearic acid, tocopherol, γ-tocopherol, squalene, n-hexadecanoic acid, and palmitic acid reported to have a therapeutic effect on cancerous cells. 32 factorial design is a type of experimental design, was utilized to optimize the nanoformulation to achieve maximum entrapment efficiency and minimum particle size. Independent factors were the chitosan and PEG concentration while dependent factors were entrapment efficiency and particle size. The optimized Buchanania lanzan oil encapsulated nanoformulation (BOCNo) has a particle size of 490.18 nm and entrapment efficiency of 59.08%. Buchanania lanzan oil and optimized BOCNo has shown significant anticancer activity against prostate cancer (PC3), lung cancer (A549), and liver cancer (MIAPACA) cell lines having IC 50 value of 9.03g/ml, 7.50g/ml, and 15.63g/ml and 11.84g/ml, 19.50g/ml, and 17.09g/ml respectively. Anticancer effect of PEG-coated nanoformulations of Buchanania lanzan oil attributed to better penetration by increased permeability and fusion of drug molecules. Buchanania lanzan oil and BOCNo have a promising cytotoxic potential against prostate cancer, lung cancer, and liver cancer by owning the presence of therapeutically active compounds which synergistically act via multiple protective mechanisms.
Ethnopharmacy and Scientification of Immunostimulants plants used by The Suwawa Tribe in Gorontalo Province and The Muna Tribe in Southeast Sulawesi Province during The Covid-19 Pandemic
Authors: Sulastri Slamet Nangsih , Mohamad Fihrina , Hartati Hartati , Isrul Muhammad
Published: December 2024

The Covid-19 virus continues to spread in different countries, including Indonesia, which has not shown a substantial decline until the present day. This has prompted the government and society to seek various methods to survive in order to maintain a prosperous life. It is recommended to consume nutritious food, beverages, supplements, or medications that contain immunostimulant substances to strengthen immunity and prevent the spread of the Covid-19 virus. Various medicinal plants worldwide, including those in Indonesia, have been scientifically proven to contain secondary metabolites such as alkaloids, flavonoids, saponins, and tannins, which exhibit immunostimulant activities. This descriptive research combines qualitative and quantitative methods, including surveys, interviews, and phytochemical screening. Its objective is to analyze the results of ethnopharmaceutical and scientification of immunostimulant medicinal plants used by the Suwawa tribe in Gorontalo Province and the Muna tribe in Southeast Sulawesi during the Covid-19 pandemic. This study involved15 informants, which divided 9 participants from the Suwawa tribe and 4 from the Muna tribe. Based on interviews and calculations of the Informant Consensus Factor (ICF) and Use Value (UV), the most frequently used plant was identified and processed into crude drugs.The phytochemical screening results revealed that the plants contained group compounds.
Dạy học chương “Một số hình khối trong thực tiễn” (Toán 7) theo định hướng giáo dục STEM
Authors: Nguyễn Văn Hồng , Nguyễn Hữu Sự
Published: December 2024

Thiết kế hoạt động dạy học chương “Một số hình dạng trong thực tiễn” (Toán 7) theo định hướng giáo dục STEM nhằm giúp học sinh phát triển năng lực, đặc biệt là khả năng ứng dụng toán học vào thực tiễn, góp phần định hướng nghề nghiệp, nâng cao chất lượng giáo dục và phát triển phong trào nghiên cứu khoa học ở trường phổ thông. Sau khi thiết kế, chúng tôi tiến hành đánh giá thực nghiệm thông qua các phương pháp: Nghiên cứu lí luận; Điều tra, quan sát; Thực nghiệm sư phạm; Thống kê toán học. Kết quả nghiên cứu cho thấy: việc dạy học môn Toán theo định hướng giáo dục STEM là cần thiết, có ý nghĩa quan trọng trong việc phát triển năng lực giải quyết vấn đề, hợp tác, tư suy cho học sinh, góp phần nâng cao chất lượng giáo dục và phát triển phong trào nghiên cứu khoa học kĩ thuật trong trường phổ thông.
Multidimensional assessment of sdi and hdi using topsis and bilinear ordering
Authors: ÇALIKOĞLU CİHAN , ŁUCZAK ALEKSANDRA
Published: December 2024

This study investigates how the Human Development Index (HDI) influences Sustainable Development (SD) in European Union (EU) countries by analyzing the relationship between the United Nations’ HDI and a newly constructed Sustainable Development Index (SDI) by the authors. The dataset comprises 18 indicators retrieved from Eurostat for 2021. The study employs the TOPSIS (Technique for Order Preference by Similarity to an Ideal Solution) approach to calculate the SDI and utilizes bilinear ordering to visualize countries in a coordinate system based on their SDI and HDI scores. Spearman’s rank correlation reveals a strong positive relationship between SDI and HDI. The study identifies disparities, with countries like Denmark and Sweden showing high SDI and HDI, while Romania and Bulgaria have lower scores. Northern and Western EU countries generally perform better, whereas Eastern and Southern countries face more challenges, highlighting the need for targeted development strategies. The results emphasize the importance of considering both human and sustainable development in policy design, offering insights for enhancing development outcomes for the EU.
Decomposing the Poor-Non-Poor Gap in the Prevalence of Undiagnosed and Untreated Hypertension Among Bangladeshi Population
Authors: Rahman Mosiur , Khatun Mahfuza , Pinkey Asrafun Naher , Haque Syed Emdadul , Liza Farhana Akhter , Haque Md. Nuruzzaman , Sarkar Prosannajid , Roy Tapan Kumar , Islam G. M. Rabiul , Alam Md. Rashed , Hasan Mahmudul , Adam Izzeldin Fadl , Duc Nguyen Huu Chau , Al-Sobaihi Saber , Hasan Abid
Published: December 2024

Objectives: Our objectives were to ascertain: the prevalence and socio-economic distribution of hypertension, as well as the rates of undiagnosed and untreated hypertension; the association between socioeconomic status (SES) and the occurrence of hypertension, as well as the rates of undiagnosed and untreated hypertension; and the factors influencing the poor-non-poor gap in terms of the prevalence, diagnosis, and treatment of hypertension.
Design: Cross-sectional nationally representative study.
Methods: Data from the 2017–18 Bangladesh Demographic Health Survey were used. 11,776 participants who were 18 years of age or older responded to our analysis. We used the wealth index as a proxy for SES. The prevalence of hypertension, both diagnosed and undiagnosed, as well as its untreated states, were the outcome variables.
Results: The age-adjusted prevalence of hypertension, undiagnosed as having hypertension, and untreated cases were 25.1%, 57.2%, and 12.3%, respectively. People in the poor SES groups had a 0.88 times (95% confidence interval [CI] 0.77–0.99) lower likelihood of having hypertension compared to those in the non-poor SES group. Individuals belonging to the poor SES group exhibited a likelihood of 1.68 and 1.53 times greater for having untreated hypertension and being undiagnosed with the condition, respectively, compared to those in the non-poor SES group. The results indicated that BMI played a role in increasing the disparity between the poor and non-poor populations concerning hypertension risk. Additionally, factors such as age, gender, and education were found to exacerbate the gap in the risk of undiagnosed hypertension between these two groups.
Conclusion: The results of this study suggest that appropriate policy measures be developed for ongoing care and early identification, especially for older adults, men, and individuals with low levels of education from low socioeconomic backgrounds. Additionally, efforts must be made to reduce the prevalence of overweight and obesity among people in the non-poor SES category.
Sağlık Çalışanlarının Karşılaştıkları Mesleki Tehlikelerin MCDM Yöntemleri Kullanılarak Değerlendirilmesi
Authors: Doğan Onur
Published: December 2024

Amaç: Bu çalışma, sağlık çalışanlarının iş yerlerinde maruz kaldıkları risk unsurlarının iş sağlığına ve güvenliğine olan etkisini değerlendirmek amacıyla yapılmıştır. Materyal ve Metot: Sağlık çalışanlarının toplum ve insanlık için öneminden yola çıkılarak işyerinde maruz kaldıkları riskler Çok Kriterli Karar Verme (ÇKKV) yöntemlerinden Entropi ve AHP yöntemleri ile değerlendirilmiştir. Entropi yöntemi, ÇKKV yöntemlerinde her bir kriterin önem düzeylerinin belirlendiği objektif bir değerlendirme yöntemidir. AHP yöntemi, birden çok alternatif arasından en iyisini seçmek için kullanılan nesnel ve öznel kararları içeren bir yöntemdir. Çalışmada kullanılan ölçüt ve alt ölçütler, alan uzmanlarının görüş ve önerileri ile literatür taraması dikkate alınarak hazırlanmıştır. Analizlerin çözümünde Microsoft Excel kullanılmıştır. Bulgular: AHP yönteminin analiz sonucuna göre en yüksek ağırlığa sahip kriter 0,351542 değeri ile C-5 psikolojik riskler olmuştur. En düşük ağırlığa sahip kriter 0,1121 değeri ile C-3 kriteri olmuştur. Entropi yönteminin analiz sonucuna göre wj değeri en yüksek olan kriter 0,273 değeri ile C-3 fiziksel riskler olmuştur. En düşük ağırlığa sahip kriter ise 0,152 değeri ile C-1 yani biyolojik riskler olmuştur. Sonuç: İş yerlerinde sağlık çalışanları için en önemli risk unsurları (AHP yöntemi) psikolojik riskler ve (Entropy yöntemi) fiziksel riskler olmuştur.
Resilience, Self-Discovery, And Black Motherhood In Terry Mcmillan’s Mama
Authors: Nithya T. , Selvaraj Dr. A.
Published: December 2024

The experiences of Black women as mothers are characterized by distinct obstacles and hardships that arise from the convergence of racism, gender inequality, and structural subjugation. In addition to navigating social expectations, stereo’types, and intergenerational trauma, they often have to deal with racism and poverty. The Black mothers have to juggle work and family obligations, handle complicated family dynamics, and put their own mental health and self-care first all while worrying about their kids’ safety and wellbeing. Terry McMillan’s novel Mama explores the themes of resilience, self-discovery, and black motherhood through the vivid depiction of the protagonist Mildred’s experiences. This novel examines how McMillan challenges dominant narratives of motherhood, race, and gender. Despite facing poverty, abandonment, and racism, Mildred’s journey showcases her determination to provide for her family and find her own identity. This novel argues that Mama is a powerful expectation of black women’s struggles and triumphs, offering insights into the complexities of motherhood and the important of self-discovery.
The Compliance of Governance on Family Data Protection Regulation
Authors: Ni Komang Sutrisni  , Putu Angga Pratama Sukma  , Embong Rahimah , Haydarov Khanlar
Published: December 2024

Digital transformation has changed the way family data is managed and stored. The vulnerability of family data has become a serious concern due to the increase in data breach incidents. This research aims to analyze public compliance with family data protection regulations and the ideality of government governance regulations regarding family data protection regulations. This research uses normative legal research methods to analyze the comparison of family data privacy protection regulations between Indonesia and England. This research examines various legal guidelines and policies by applying legislative techniques and a conceptual approach. The legal system theory is used as an analytical framework to evaluate the effectiveness of regulations, law enforcement, and legal culture's influence on public compliance. Data was collected through a literature review of primary and secondary sources, including documents, archives, books, and scientific research findings. The research results show First, that family data protection regulations in England are first more standardized with a higher level of public compliance than in Indonesia. Secondly, Indonesia still faces challenges such as the weak bargaining position of data subjects, the absence of clear guidelines for data controllers, and the need for an independent oversight authority. This research recommends regulatory improvements, the establishment of competent authorities, and enhanced public education to strengthen Indonesia's personal data protection system, particularly family data.
«Italia libera, Radetzky non volle». Tra autonomia e iconoclastia: le monete del Governo provvisorio di Lombardia
Authors: Giunchedi Luca
Published: December 2024

«Italia libera, Radetzky non volle». Tra autonomia e iconoclastia: le monete del Governo provvisorio di Lombardia
Amara Terra. Donne migranti, sfruttamento e forme di resistenza nelle campagne siciliane
Authors: Massari Monica , Cabras Federica , Miceli Simona
Published: December 2024

Le migrazioni sono una faccenda dei corpi e dei sentimenti (…). Avvengono nel tempo e nello spazio, promettono, annunciano, coronano un sogno, liberano, mettono a soq-quadro i territori d’arrivo e di partenza, costringono a ripensarli e a ridisegnarli come un terzo luogo ancora non dato. Ecco perché raccogliere i racconti e le riflessioni di braccianti, mediatrici, operatori e operatrici sociali, sindacalisti incontrati sul terreno e metterli in risonanza con le parole di intellettuali e artisti di ogni parte del mondo (…) produce una fertile messa a fuoco (dalla Prefazione di Maria Nadotti).
EVALUATION OF FENUGREEK (TRIGONELLA FOENUM-GRAECUM L.) GERMPLASM UNDER SUBTROPICAL CLIMATE CONDITIONS OF FAISALABAD
Authors: IQBAL M , RASHID K , RASHID K , HAMMAD G , ALI A , LATIF A , AMIN E , TAHIR M , SHABBIR RH , ASLAM R , Din N , ANWAR MF , AFFAN QM
Published: December 2024

Fenugreek (Trigonella foenum-graecum L.) commonly known as methi, is a self-pollinating, leguminous crop native to the subcontinent and the Eastern Mediterranean region. An experiment was conducted to evaluate nine genotypes in Faisalabad region during year 2022-23.The study highlighted significant variations among fenugreek genotypes, with MethiQasoori (Check) being the fastest to first cutting at 40.2 days. Other quick-maturing varieties included Fenu-06 and Fenu-05, while Fenu-07 and Fenu-02 took longer. For the second cutting, MethiQasoori also led at 70.2 days. Fenu-04 was the tallest at 90.1 cm and had the highest leaf yield of 23.62 T/Ha. EFG-1144A had the lowest yield at 7.88 T/Ha. Fenu-04 had the highest 1000 seed weight at 1.333 g, indicating potential for better seed quality. Yellow flowers found in Fenu-04, MethiQasoori, Fenu-02, Fenu-01, and EFG-1144A, indicating a preference or trend towards yellow flowers in several varieties. White flowers had been found in Fenu-06, Fenu-05, Fenu-03, and Fenu-07, suggesting that white flowers was less common. All varieties were vulnerable to aphids, emphasizing the need for pest management.
Analisa re-mapping ECU terhadap performa dan emisi gas buang pada motor injeksi Scoopy 110
Authors: Handriyanto Rian , Ponidi Ponidi
Published: December 2024

Menanggapi kemajuan pengetahuan otomotif yang semakin meningkat dan meningkatnya rasa ketidakpuasan terhadap peningkatan performa sepeda motor diatas standar. Pengendara sepeda motor biasanya memodifikasi sepedanya untuk meningkatkan performa. Penelitian ini bertujuan mengetahui pengaruh re-mapping ECU (Engine Control Unit) terhadap performa dengan memajukan ignition timing sebesar 0.5°, 1°, 1.5°, 2°, 2.5°, 3° pada putaran 1500 – 9500 RPM dan emisi gas buangnya. ECU yang digunakan ECU standar pabrik kemudian dilakukan re-mapping pada ignition timing. Hasil pengujian didapatkan torsi dan daya terbaik sepeda motor Scoopy dengan memajukan ignition timing sebesar 1° dengan hasil daya 7,4 HP pada 7000 RPM meningkat 0,4 HP, torsi 10,45 N.m pada 4500 RPM meningkat 0,77 N.m. Dimana Scoopy 110 dengan ECU standar memiliki daya 7,0 HP pada 7000 RPM, torsi 9,68 N.m pada 4500 RPM. Fuel consumption terbaik dengan memajukan ignition timing sebesar 3° senilai 0,297 (kg/h). Spesific fuel consumption terbaik dengan memajukan ignition timing sebesar 3° senilai 0,413 (kg/HP.h). Efisiensi termal terbaik dengan memajukan ignition timing sebesar 3° senilai 1,471%. Emisi gas buang terendah dengan memajukan ignition timing sebesar 3° senilai CO 0,34% dan HC 127 PPM.
Análise da Participação Democrática no Plano de Diretor de Londrina a luz da Teoria de Raymond quanto aos níveis de participação da sociedade civil
Authors: Spiri Ferreira THIAGO , Antonello Ideni Terezinha , STEFANI SILVIO ROBERTO
Published: December 2024

A participação da sociedade civil contribui para a geração de ideias, o acompanhamento e fiscalização das ações dos agentes públicos, um instrumento que auxilia a gestão do planejamento urbano é o plano diretor, que é uma obrigação de alguns municípios com períodos de aplicação em dez anos, englobando todas as áreas que compõem a cidade. A participação democrática inclui atores como os cidadãos, os representantes da comunidade e os agentes públicos tomadores de decisões, em debates com foco em soluções para o desenvolvimento e crescimento regional. O objetivo do estudo foi analisar qual o nível de participação da sociedade civil no plano diretor da cidade de Londrina. O estudo evidenciou que a participação da sociedade civil para a cidade de Londrina está no nível de “Gestão participativa”, próximo ao nível máximo de participação proposto por Raymond. As limitações do estudo são pelo campo teórico e análise documental, porém contribui para uma referência em nível de participação com as ações realizadas pelos gestores públicos responsáveis pelo desenvolvimento do plano diretor em busca da participação da comunidade.
An Action Research Approach to the Design and Implementation of an On-line Course in Applied Mechanics
Authors: Allinson Anthony J.
Published: December 2024

Since the establishment of democratic government in South Africa, tertiary education has been experiencing profound changes in its structure, governance, demographics and environment. This paper describes an action research approach to the design and implementation of an on-line course in Applied Mechanics, during rapid change in structural, human and technological environments. The action research approach enabled the design to be responsive to the environmental change, and to direct the design while serving as a working example of action research for professional development. The project was carried out as part of an on-line collaborative professional development programme. It has also been valuable as a means of documenting and viewing the design.
Various Approaches to Successful E-learning Implementations
Authors: Baloglu Arzu
Published: December 2024

The main objective of this paper is to present a critical review concerning some advice concerning e-learning implementation. Training or web based learning will become one of the most important sectors in future. The purpose of this study is to suggest workable guideline to adapt e-learning to the practical needs and conditions of the business sector.
A Global economy needs the capacity to constantly update the education and essential skills of its work force. That is why web based training projects are being supported by government, lecturers and the private sector. However, when e-learning programs have been successfully implemented, they have known increased productivity and than they saw that it met the expectation of management. When the implementation is unsuccessful, investment on various components such as time, resource and capital can be wasted. That is why there are some critical factors which need to be taken into account. We are learning from the experience of those who have applied various methods in their workplace.
In this paper, together with a working definition of e-learning and its importance as well as factors critical for success various approaches to its satisfactory implementation have been included. Later on we use conclusion with a critical requirement and a number of individual suggestion for improvement.
Finally, we document improvements, which have resulted from the application of several different approaches to training in e-learning.
A Researchers Paradise
Authors: Burchardt Jørgen
Published: December 2024

Services for research are still in the early days of development and adoption by scholars. Over the next years many new methods willemerge. These new scholarly resources may be very different in form and function than their current manifestations.Focus will be on research as such. The first part of the paper will outline its relations to learning, e-learning and knowledgemanagement. A theoretical framework will be presented within which the new possibilities for the development of the research canbe understood.This paper is then a preliminary attempt to map out some of the key contexts within which the scholarly resources will exist. I willexamine the emerging role and fit of the different services in scholarly scientific practice - including examples of the ‘best practice’within the field- the range of dimensions that shape their usage and provide value for scholars, and the larger impact on scholarlypractice.In the final section, I present insights on the adoption and implications for the future.
Play and its Role in Online Learning
Authors: Thomas Hilary
Published: December 2024

From within the context of a creative writing programme, this paper develops the idea of ‘playing’ as an approach to learning andcreativity. It raises questions, however, about how playing might take place in a defined online environment. It argues that as well asa tool for learning, play can have an impact on social and motivational development. The suggestion is made that issues raised havetransfer to other domains.
From Distance Education to e Learning
Authors: Venkatachary Ranga
Published: December 2024

The questions addressed in this paper stem from the paradigm shift which engendered ‘life long’ learning. Distance Educationmodels and e Learning practice share the philosophical framework of Open Learning. The design imperatives of e Learning havebeen shaped by ICT. The divergence as a design imperative is of relative significance. The principle of ‘theory neutrality’ indesigning reusable learning objects is questionable from the viewpoint of instructional efficacy. The paper argues that scope andsequence are significant factors in the process of designing learning objects. They determine the bonding characteristics of theobjects and thus dictate the manner of their reusability.
Reinterpreting the LearnDirect Model to Achieve Successful Communities of Practice
Authors: Hramiak Alison
Published: December 2024

For many students, the specific requirements of their cultural background can serve as a barrier to realising their learning potential. In such cases, the distance to an educational establishment may be more a cultural than geographical mile. Technology may, for some, be the only way to travel this mile, and thus enable learning to take place where once it might have not.
Group Modelling Method in Web-Based Collaborative Learning Environment
Authors: Zhao Jianhua , McConnell David
Published: December 2024

Collaborative learning (Damon, 1984; Gabbert et al. 1986; Johnson and Johnson, 1989; Johnson et al. 1991; Kadell and Keehner, 1994; Kaye, 1991; Klemm, 1994; Webb, 1982) is the idea that small, interdependent groups of students work together as a team to help each other learn. So small learning group plays a very important role in collaborative learning process, especially in web-based collaborative learning environment. Many collaborative learning methods were explored and introduced by some researchers (Slavin, R., Sharan, S., Lazarowitz, R. H., Webb, C., and Schmuck, R., 1985; Slavin, R. E., 1995). To utilize collaborative learning approach in classroom-based environment also got a considerable success. But how to find an optimal approach to simulate collaborative learning process in web-based learning environment already became a question. Some researchers (Aiken, M. W., 1993; Klemm, W. R. & Snell, J. R., 1996; Dillenbourg, P., 1999; Tsoi, M. F., Goh, N. K. and Chia, L. S., 2000) already did a lot of work for it. The purpose of this research was focused on how to find an approach to simulate learning groups in web-based collaborative learning environments.
Navigating the Orthopaedic Maze as a New Patient: A National Mystery Caller Study on Medicaid Coverage and Access to Specialized Surgeons
Authors: Felan Nicholas A. , Garcia-Creighton Elizabeth , Hirpara Ankit , Narváez Isabella , Miller Adam , Batiste Alexis J. , Stokes Daniel J. , Tseng Ryan , Santiago Alessandra , Smyth Anthony , Pulciano Nicholas R. , Wharton Benjamin R. , McCarty Eric C. , Muffly Tyler M.
Published: December 2024

Introduction:

Medicaid coverage is associated with longer appointment wait times, decreased access to care, and poorer health outcomes compared with private insurance across medical subspecialties. The purpose of this study was to evaluate new patient appointment wait times for subspecialty Orthopaedic care based on insurance type and to identify factors influencing these wait times.

Methods:

Orthopaedic physicians were identified using the American Academy of Orthopaedic Surgeons patient-facing database in the fields of Adult Reconstruction, Foot and Ankle, Hand, Sports Medicine, Spine, Pediatric, and General Orthopaedic surgery. Mystery callers, posing as patients with either Medicaid or Blue Cross/Blue Shield (BCBS) insurance, contacted physicians to request the next available new patient appointment. The business days until the first available new patient appointment were recorded and analyzed using a linear mixed Poisson model.

Results:

A total of 1,002 phone calls were made to 501 unique physicians in 47 states. Among the 349 physicians meeting inclusion criteria, 37% (n = 130) did not accept Medicaid. Medicaid patients experienced a 10% longer wait for a new patient appointment compared with patients with BCBS (incidence rate ratio: 1.10; CI: 1.05 to 1.15; P < 0.01) with mean wait times of 24.9 business days (SD ± 24) and 19.6 business days (SD ± 23), respectively. Increased waiting times were also associated with academic institutions (P < 0.01), prolonged call times (P < 0.01), and specific geographic regions (P < 0.05). Our model achieved an R-squared value of 0.94, demonstrating strong explanatory power.

Conclusion:

Patients with Medicaid experience longer wait times and decreased access to care when scheduling an appointment with an Orthopaedic surgeon compared with patients with private insurance. This may be due to reimbursement structures in Medicaid that do not cover the full cost of treatment. Aside from advocating for higher reimbursement rates, telehealth initiatives may help bridge this gap to ensure accessibility to orthopaedic surgery for all patients.
Implementation of Ethnomathematics in Banten Mukarnas Batik Motifs in Improving Students' Mathematical Creative Thinking Skills at MTs Al-Khairiyah Rancaranji Padarincang
Authors: Kusuma Jaka Wijaya , Caesarani Sarah , Wulandari Resi
Published: December 2024

This research aims to explore the implementation of Ethnomathematics of Banten Mukarnas batik motifs in improving students' mathematical reasoning and creative thinking skills. Ethnomathematics was chosen to connect mathematical concepts with local culture so that students can see the relevance of mathematics in everyday life. The method used in this study is a quasy experiment with a Pretest-Postest Control Group Design. The sample was selected using random sampling technique. The data collection technique was carried out by providing test questions for students' mathematical creative thinking ability. The analysis was carried out quantitatively on the learning process and measuring students' creative thinking skills before and after the application of Ethnomathematics. From the results of the posttest data analysis of the experimental and control classes, the sig. (2-tailed) of 0.001 < 0.05 and an average of 89.42 in the experimental class, while in the control class, the average was 76.61. So, it can be concluded that there is a difference in the ability of students to think creatively and mathematically using the ethnomathematics-based learning model assisted by the Banten Mukarnas batik motif compared to students who obtain the conventional learning model
Cross-cultural Study of the Concepts of "Shame" and "Guilt" in English and Romanian
Authors: Lifari Viorica
Published: December 2024

The study of concepts has become a necessity in the context of globalization and intercultural communication. At the time when specialists in Cultural linguistics identified the fact that apparently similar words in at least two languages are associated with different mental models there appeared a need to clarify this issue so as to avoid miscommunication on the intercultural level as well as leave behind intercultural conflicts. “Embarrassment” and “guilt” are of special interest for the researchers as often these concepts are confused or considered synonyms in some languages and cultures, letting alone the different types of societies; here we refer to the individualistic, collectivistic or mixed types of societies. This research is an attempt to conduct an interdisciplinary and cross-cultural study based on the English and Romanian Languages. We use the method of definition, that of cognitive prototipic scenario and the Natural Semantic Metalanguage to investigate the mentioned concepts in two cultures and to avoid ethocentrism. The results of the study show that what matter most in an individualistic type of society are the conventions and less the moral values, thus “shame” and “guilt” were gradually transformed into “embarrassment”, while in the mixed types of societies or collectivistic ones “shame” is gradually substituted by “guilt”.
“They Transfigured the Earth, and Made it Eden Again” – Poetic Alchemy in Nathaniel Hawthorne’s the House of the Seven Gables
Authors: Dubsky Irina
Published: December 2024

The present paper aims to propose a reading of The House of the Seven Gables: A Romance – singled out by T. S. Eliot as “Hawthorne’s best novel” – as a story of initiation and alchemical transmutation, alchemy being understood here as existential poetry, not as the mere conversion of base metals into the gold of the wise. This interpretation is articulated by means of an analysis of the system of the hermetic symbols encoded in the text. Moreover, the heroes and heroines in the story are endowed with attributes which easily lend themselves to an interpretation through the grid of hermetism as they are involved in a mystery drama the significance of which is a mirroring of their progress towards illumination and inner blossoming. Unbeknownst to them, the characters have embarked on a journey of self-realization. The fictional universe unfolds under the sign of an interplay of light and shadows meant to bring to the fore the meaning of the story as one of upward spiritual transformation and advancement towards limpidity and harmony. The lines of the characters’ fictional destinies seem to converge into a climactic point which marks the state of inner fulfillment, the consummation of Magnum Opus, the Great Work of the alchemists.
Stylistic Consistency in the Translation from Romanian into French
Authors: Ceban Tamara
Published: December 2024

The stylistic consistency in the text translation may be characterized by unexpected kinds of turn of expression and solutions which, in turn, require the use of various translation techniques. In this paper we have limited ourselves to the analysis of the French versions of three Romanian prose texts because prose can best illustrate the translation techniques and exemplify the particulars of a given discourse in a significant way. We have selected three Romanian authors : Liviu Rebreanu’s novel Răscoala (The Uprising) - in which the author employs a discourse which is more or less neutral from the perspective of the translation methods ; Vasile Voiculescu, Povestiri (Tales) – whose style is much more heavily marked through the local and poetic translation techniques ; Ion Creanga’s fairy-tale Soacra cu trei nurori (The Mother-in-law and her Three Daughters-in-law) in which one can identify his picturesque discourse in the translation of which several translation methods such as the equivalence, the modulation and the adaptation have been employed. In conclusion, after a brief analysis of the stylistic consistency of the three texts under analysis, we will highlight the relationship established between the discourse type and the translation methods employed in the French language.
The Necessity for Systematic Faculty Training in Higher Education Field
Authors: Marinescu Valeriu
Published: December 2024

In compliance with the effective legislation (“Higher Education Act no. 199/2023”), in Romania, students are the direct beneficiaries of the educational process and learning must be centred on the student, on their needs and interests, as set forth by the European Standards and Guidelines for Quality Assurance in Higher Education. This aspect requires appropriate recruitment and development of the teaching staff who are familiar with and employ in a flexible manner diverse, modern and interactive teaching methods that motivate the students to learn, but also objective criteria and proper techniques for student assessment. This article reflects the author's experience as an ARACIS (the Romanian Agency for Quality Assurance in Higher Education) evaluator, but also his skills developed following the completion of the “Quality, Innovation, Communication in the system of continuous training of higher education teaching staff” postgraduate programme organised by the Ministry of Education (in Romania). The higher education teaching staff must periodically participate in training sessions towards the improvement of their teaching and assessment competencies. During the assessment of the university programmes of studies and during institutional evaluations, Romanian Agency for Quality Assurance in Higher Education (ARACIS) analyses the compliance with the legal provisions and focuses on the level of satisfaction of the students in Romania in terms of their academic experience.
The methodical Letter: Initial Training Instrument for Future Early-Childhood Education Teachers in Romania
Authors: Dumbravescu Daiana-Georgiana , Merino Mañueco Susana
Published: December 2024

It is now an established practice for the Romanian education authorities to send to Romanian early childhood education institutions (nurseries and kindergartens), a document called methodical letter, regardless of whether they are public or private institutions, on an annual basis. This letter contains a number of recommendations regarding the Curriculum pentru educație timpurie (Curriculum for early education). The Curriculum pentru educație timpurie is the basis of national education at pre-primary level. The methodical letter written by national institutions, with a relatively fixed structure, sets out a number of issues and recommendations for better implementation of the national curriculum, as well as issues for discussion of teaching practice in the classroom. In this article, we aim to investigate the last five methodical letters in the perspective of considering them as pedagogical and didactic resources for students during their internship period. Both students in initial training, as well as Educational agents (Galisson, 1990) who teach at the pre-school level can find in these documents a useful and necessary training tool for the teaching career. We believe that the methodical letters can be useful for students - future educators to consolidate their knowledge about the educational process in the classroom as well as to consider their professional-teaching competences and, implicitly, to gain a better understanding of the teaching practice they observe and analyse during the different internship periods.
Writers and Books that Safeguarded National Identity
Authors: Marinescu Mihaela
Published: December 2024

Defending the Latin origin of the Romanian people and language, as well as highlighting the position held by our people within the context of the European civilization, has been a focal point of the activity of our scholars throughout the centuries. The space between the Carpathians, the Danube and the Black Sea has represented, in the course of time, a space of transition, influenced by models taken over throughout the centuries. The Romanian people became a bridge between civilizations, the cultures and mentalities coalesced and the Romanians responded in two different ways to this phenomenon, by developing two entirely different kinds of attitudes: one of total rejection (involving a state of isolation and self-closure) and one of receptiveness – sometimes exaggerated. The XXth century added new dimensions to the process of language cultivation, as the number of scholars striving to preserve the national identity increased. The problem of maintaining our national identity by cultivating the language was regarded as highly relevant for our people and this is precisely the reason why such luminaries as Bogdan Petriceicu Hasdeu, Mihai Eminescu, Nicolae Iorga a.o., in order to convey their views, resorted to the mass media form with the highest impact at the time: print journalism.
Polymorphisms in the leptin gene and their role in adolescent obesity and metabolic health
Authors: Tanzila Raden , Irfannuddin Irfannuddin , Kesuma Yudianita , Liberty Iche , Hartanti Miranti , Mayasari Ni , Anggraini Wieke , Chairani Liza , Prameswarie Thia , Ramayanti Indri , Aristi Wulan , Larasari Delvi
Published: December 2024

The leptin (LEP) gene polymorphism is one of the most common polymorphisms and is believed to be associated with high circulating LEP levels that can occur in obese individuals. Thus, this study purposed to determine the relationship of LEP1 and LEP2 gene polymorphisms with overweight/obese and non-obese adolescents in Palembang and their correlation with various metabolic and anthropometric parameters. This research was an analytical and observational study. A total of 50 blood samples from adolescents (aged 10-18 years) were analyzed in this study. Standard laboratory protocols for serum lipid measurements, deoxyribonucleic acid (DNA) extraction, allele analysis by polymerase chain reaction (PCR), and LEP and insulin analysis by enzyme-linked immunosorbent assay (ELISA) were employed. The study revealed the allelic frequencies for gene LEP1: non-obese (G = 0.45, A = 0.55) and obese (G = 0.87, A = 0.13), and gene LEP2: non-obese (G = 0.54, A = 0.45) and obese (G = 0.67, A = 0.33). The frequencies of alleles in the LEP1 gene showed a statistically significant association with nutritional status (p = 0.011), while there was no significant association between genotypes in the LEP gene and nutritional status. The level of LEP was 6.39 + 1.12 in non-obese and 11.57 + 1.68 in obese, with p 0.000; and the triglyceride level was 82.56 ± 43.22 in non-obese and 113.72 ± 54.03 in obese, with p 0.029. In conclusion, this study shows that LEP levels and the polymorphism in the LEP1 gene are associated with obese adolescents.
Antibacterial activity of camel colostrum against pathogenic strain of Escherichia coli F17-associated with calf diarrhea
Authors: Bessalah Salma , Faraz Asim , Mustafa Ayman , Hussain Syeda , Saeed Shamsaldeen , Liaqat Chanda , Ashraf Waqas , Iqbal Zeeshan , Akbar Muhammad , Hammadi Mohamed
Published: December 2024

Background:
Many protective proteins, including lactoferrin and heavy chain antibodies, are present in camel colostrum, giving it a distinctive composition. Beyond a broad spectrum of pathogens, these proteins demonstrate antibacterial properties.

Aim:
The current research assessed the prophylactic properties of camel colostrum against Escherichia coli F17.

Methods:
A microbroth dilution method was employed to assess the efficacy of camel colostrum, whereas a crystal violet assay was utilised to determine its antibiofilm potential. Extracellular deoxyribonuclease acid (eDNA) release, swarming, and swimming motilities were also examined.

Results:
The results showed that camel colostrum significantly reduced E. coli-F17 growth by 70% and above at different incubation periods (6 - 24h). The rate of cell attachment gradually decreased from approximately 40% to 24% as the concentration increased from 12.5 to 50 mg/mL. E. coli-F17 developed a biofilm at a rate of 54.8% when exposed to 50 mg/mL of camel colostrum. In contrast, the greatest level of biofilm formation against the tested bacteria (94%) was observed at a concentration of 1.5 mg/mL. A halo zone of camel colostrum ranging from 10 to less than 30 mm at concentrations between 6 and 50 mg/mL also inhibited swimming and swarming capabilities. The treated cells yielded no eDNA.

Conclusion:
According to these results, camel colostrum inhibits the growth of E. coli-F17 by impeding the swarming and swimming motilities, and biofilm formation. Additionally, camel colostrum incubation with E. coli-F17 diminishes eDNA. To evaluate the potential protective effects of camel colostrum in an animal model, additional research is recommended.
Biological markers as an additional method of determining drowning
Authors: evi Emina , i Nina , i Ermin , Katica Muhamed , uta Nedim , Spahi Edina , Lazovi Edina , i Aida
Published: December 2024

Background:
There is no specified diagnostic procedure that can help in determining the cause of death and the diagnosis of drowning because the pathohistological signs are almost identical and non-specified.

Aim:
Our study aims to recognize and prove diatoms appearance in organs from a forensic aspect in Bosnia and Herzegovina, and to examine which is the more specific method in the diagnosis of drowning, the diatom test or the pathohistological finding.

Methods:
Rats of the recommended body weight were divided into four groups: G1 (n=8; mechanism of death - asphyxia; cause of death - suffocation, submerged 1 hour after death); G2 (n=8: mechanism of death-asphyxia; cause of death-suffocation, immersed 72 hours after death); G3 (n=8: mechanism of death-asphyxia; cause of death-drowning, autopsy immediately after death) and G4 (n=8: mechanism of death-asphyxia; cause of death-drowning, post mortem 24 hours after death).

Results:
During the diatom analysis, four species of diatoms, Diatoma vulgaris, Melosira varians, Epithemia adnata, and Cymbella sp, were successfully recovered from the stomach. Microscopic analysis did not detect diatoms in the kidneys and brains of rats, while the pathohistological changes were relatively uniform.

Conclusion:
Our results propose that the diatom test is a sustainable tool for supporting the diagnosis of drowning in the forensic pathology analysis of the cause of death. This experimental study is a starting point towards the optimization of tests and sampling in cases of unexplained etiology.
Recurrence rate of corneal squamous cell carcinoma in dogs undergoing superficial keratectomy surgery
Authors: Mather Helen , Stanley Robin
Published: December 2024

Background:
Corneal squamous cell carcinoma (cSCC) is a rare neoplasm of dogs that can be treated with various modalities, principally by superficial keratectomy (SK) surgery. It is common to treat cSCC with multiple adjunctive therapies, but this may not always be practical for clinicians, clients, or patients.

Aim:
This retrospective study describes the signalment of affected dogs, concurrent medical therapy, and success rate of surgical treatment of cSCC with SK surgery alone or in combination with adjunct therapy.

Methods:
Eligible dogs undergoing SK surgery for histologically confirmed cSCC were selected from medical records (2009-2024) of Animal Eye Care, Melbourne. Records were examined for cSCC recurrence at follow up.

Results:
Between January 2009 and August 2024, 16 eyes from 14 dogs (5 male; 35.7% (37.5% eyes), 9 female; 64.3% (62.5% eyes) had a confirmed histopathological diagnosis of cSCC following SK surgery. All cases were diagnosed within the last nine years. There was a notable predilection of brachycephalic breeds (85.7% of dogs; 81.3% eyes) with pugs the most overrepresented (42.9% of dogs; 37.5% of eyes). The average age at diagnosis was 8.7 years (range 2.1 – 13.8). Tumour recurrence occurred in two cases following incomplete excision, with no tumour recurrence reported following a second SK surgery. Adjunctive therapy was used in four cases and included cryotherapy and topical interferon alpha-2a. At the time of diagnosis, 12 out of 16 eyes had been treated previously with topical immunomodulatory therapy. Prevalence data varied but peaked in 2021 with 0.14% of total patients and 0.82% of all brachycephalic patients diagnosed with cSCC.

Conclusion:
Complete excision of cSCC by SK surgery is effective for preventing the recurrence of cSCC in dogs, even in the absence of adjunctive therapies. Dogs with chronic corneal inflammatory conditions, particularly brachycephalic breeds, are at higher risk for developing cSCC. Corneal SCC should be suspected in middle aged brachycephalic dogs presenting with proliferative, raised, or hyperaemic corneal lesions.
In vitro evaluation of the antimicrobial efficacy of Eupatorium odoratum ethanol extract against Gram-positive and Gram-negative bacterial strains
Authors: Amri Indah , Isnaeni Purnaning , Sabri Jasni
Published: December 2024

Background:
Eupatorium odoratum L (Siam weed) is a highly invasive species that contains various beneficial active compounds. This study was conducted to explore the antibacterial properties of E. odoratum ethanol extract against gram-positive and gram-negative bacteria.

Aim:
The aim of this study was to evaluate the antibacterial activity of E. odoratum ethanolic extract against various gram-positive and gram-negative bacteria to assess its potential as an antimicrobial agent.

Methods:
The study employed the agar well diffusion method to measure the antimicrobial effectiveness of the E. odoratum ethanolic extract. Additionally, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined using the broth microdilution assay for different bacterial strains.

Results:
The results showed that the E. odoratum ethanol extract could not inhibit Escherichia coli and Klebsiella pneumoniae. It presented weak to moderate inhibition against Bacillus subtilis, Enterococcus faecalis, and Proteus vulgaris, and exhibited moderate to strong inhibition against Staphylococcus aureus. The MIC and MBC of the E. odoratum ethanolic extract against B. subtilis, S. aureus, E. faecalis, E. coli, P. vulgaris, and K. pneumoniae were 12.00 mg/ml and 12.00 mg/ml; 5.00 mg/ml and 7.50 mg/ml; 15.46 mg/ml and 18.98 mg/ml; 75.00 mg/ml and 87.50 mg/ml; 25.00 mg/ml and 25.00 mg/ml; and 77.50 mg/ml and 100.00 mg/ml.

Conclusion:
It was concluded that while E. odoratum ethanolic extract showed moderate to strong effectiveness against S. aureus, it was less effective against other gram-positive bacteria and showed no activity against the tested gram-negative bacteria. Therefore, the ethanolic extract of E. odoratum was considered to have potential as an antimicrobial agent, particularly against S. aureus.