bluuebunny/crossref_metadata_2025 huggingface dataset:
UPGRADED INFORMATION AND COMPUTING CONTROL SYSTEM OF THE NOVOVORONEZH NPP UNIT 4
Authors: Самодеенко А.А. , Синюков Д.С. , Иванников А.А.
Published: August 2024

Приведены результаты обязательной модернизации информационно-вычислительной системы управления, выполненной при продлении срока действия энергоблока № 4 Нововоронежской АЭС. Проблема была решена на основе принципа унификации. Программное обеспечение всех компонентов программно-технического комплекса информационно-вычислительной системы, включая функции систем предоставления параметров безопасности и внутриреакторного контроля, реализовано на единых программных средствах.

The results of the mandatory upgrading of the information and computing control system, performed during lifetime extension of the Novovoronezh NPP unit 4, are presented. The problem was solved on the basis of the principle of unification. The software of all components of the software and hardware complex of the information and computing control system, including the functions of systems for providing security parameters and in-reactor control, is implemented on unified software tools.
Annulation Producing Diverse Heterocycles Promoted by Cobalt Hydride
Authors: Sugimura Takuma , Yamada Ren , Kanna Wataru , Mita Tsuyoshi , Maeda Satoshi , Szarłan Bartłomiej , Shigehisa Hiroki
Published: August 2024

This study demonstrates the efficient synthesis of various heterocycles using the metal hydrogen atom transfer (MHAT)/ radical-polar crossover (RPC) method, emphasizing its versatility under mild conditions with high functional group tolerance. By distinguishing between cyclization and annulation, we underscore the complexity and efficiency of this approach in constructing intricate molecular architectures. Notably, the incorporation of an acetone solvent in the formation of cyclic acetal dioxanes from homoallylic alcohols reveals a novel annulation mechanism. Extensive substrate scope analysis and density functional theory calculations provide insights into reaction pathways, highlighting the critical role of cationic alkylcobalt(IV) intermediates and collidine in product selectivity. This study elucidates the mechanisms of the MHAT/RPC method and showcases its potential as a robust alternative to conventional synthetic strategies.
Structure-activity relationship of inositol thiophosphate analogs as allosteric activators of Clostridioides difficile toxin B
Authors: Cummer Rebecca , Grosjean Félix , Bolteau Raphaël , Vasegh Seyed Ehsan , Veyron Simon , Keogh Liam , Trempe Jean-François , Castagner Bastien
Published: August 2024

Clostridioides difficile is a bacterium that causes life-threatening intestinal infections. Infection symptoms are mediated by a toxin secreted by the bacterium. Toxin pathogenesis is modulated by the intracellular molecule, inositol-hexakisphosphate (IP6). IP6 binds to a cysteine protease domain (CPD) on the toxin, inducing auto-proteolysis, which liberates a virulence factor in the cell cytosol. We developed second-generation IP6 analogs designed to induce auto-proteolysis in the gut lumen, prior to toxin uptake, circumventing pathogenesis. We synthesized a panel of thiophosphate-/sulfate-containing IP6 analogs, and characterized their toxin binding affinity, auto-proteolysis induction and cation interactions. Our top candidate was soluble in extracellular cation concentrations, unlike IP6. The IP6 analogs were more negatively charged than IP6, which improved affinity and stabilization of the CPD, enhancing toxin auto-proteolysis. Our data illustrate the optimization of IP6 with thiophosphate biomimetics which are more capable of inducing toxin auto-proteolysis than the native ligand, warranting further studies in vivo.
Exploration of the Global Minimum and Conical Intersection with Bayesian Optimization
Authors: Somaki Riho , Inagaki Taichi , Hatanaka Miho
Published: August 2024

Conventional molecular geometry searches on a potential energy surface (PES) utilize energy gradients from quantum chemical calculations. However, replacing energy calculations with noisy quantum computer measurements generates errors in the energies, which makes geometry optimization using the energy gradient difficult. One gradient-free optimization method that can potentially solve this problem is Bayesian optimization (BO). To use BO in geometry search, an acquisition function (AF), which involves an objective variable, must be defined suitably. In this study, we propose a strategy for geometry searches using BO and examine the appropriate AFs to explore two critical structures: the global minimum (GM) on the singlet ground state (S0) and the most stable conical intersection (CI) point between S0 and the singlet excited state. We applied our strategy to two molecules and located the GM and the most stable CI geometries with high accuracy for both molecules. We also succeeded in the geometry searches even when artificial random noises were added to the energies to simulate geometry optimization using noisy quantum computer measurements.
State-of-the-art local correlation methods enable affordable gold standard quantum chemistry for up to hundreds of atoms
Authors: Nagy Peter
Published: August 2024

We review the current capabilities of local electron correlation methods up to the coupled cluster model with single, double, and perturbative triple excitations [CCSD(T)], which is a gold standard in quantum chemistry. The main computational aspects of the local method types are assessed from the perspective of applications, but the focus is kept on how to achieve chemical accuracy (i.e., <1 kcal/mol uncertainty), as well as on the broad scope of chemical problems made accessible. The performance of state-of-the-art methods are also compared, including the most employed DLPNO and, in particular, our local natural orbital (LNO) CCSD(T) approach. The high accuracy and efficiency of the LNO method makes chemically accurate CCSD(T) computations accessible for molecules of hundreds of atoms with resources affordable to a broad computational community (days on a single CPU and 10–100 GB of memory). Recent developments in LNO-CCSD(T) enable systematic convergence and robust error estimates even for systems of complicated electronic structure or larger size (up to 1000 atoms). The predictive power of current local CCSD(T) methods, usually at about 1–2 order of magnitude higher cost than hybrid density functional theory (DFT), has become outstanding on the palette of computational chemistry applicable for molecules of practical interest. We also review more than 50 LNO-based and other advanced local-CCSD(T) applications for realistic, large systems across molecular interactions as well as main group, transition metal, bio-, and surface chemistry. The examples show that properly executed local-CCSD(T) can contribute to binding, reaction equilibrium, rate constants, etc. which are able to match measurements within the error estimates. These applications demonstrate that modern, open-access, and broadly affordable local methods, such as LNO-CCSD(T), already enable predictive computations and atomistic insight for complicated, real-life molecular processes in realistic environments.
Introdução à Filosofia: Uma Interpretação a Partir de Sócrates
Authors: Paula Marcio Gimenes de
Published: August 2024

O presente livro é fruto de aulas ministradas nos cursos de graduação da Universidade de Brasília, especialmente nas disciplinas Introdução à Filosofia e Introdução à História da Filosofia. O intuito principal da disciplina – e agora do livro - é bastante simples: apresentar uma pequena introdução à Filosofia por meio de um dos seus mais conhecidos personagens, a saber, Sócrates. Para tanto, o primeiro capítulo propõe uma análise da figura de Sócrates por meio dos seus intérpretes mais tradicionais, a saber, Xenofonte, Aristófanes e Platão. O segundo capítulo segue a avaliação da temática agora por meio das interpretações de Werner Jaeger, Hegel, Kierkegaard e Nietzsche. O livro é concluído com uma avaliação comparativa entre as interpretações antigas, modernas e contemporâneas e conta ainda com um apêndice denominado "De Atenas à Ribeiro Preto: da democracia grega à democracia corintiana", um breve experimento dedicado ao ilustre Sócrates do Brasil. Ressalte-se que o trabalho conta ainda com uma apresentação feita por Felipe Ramos Gall.
Geografia política: base conceitual e diversidade temática
Authors: Azevedo Daniel A. de , Nogueira Ricardo
Published: August 2024

O livro visa preencher uma lacuna na Geografia Política brasileira na medida em que busca analisar o espaço geográfico como produto e condicionante do poder político, enfatizando sua dimensão espacial, compreendendo a política como práticas sociais discursivas e a materialidade dada pela singularidade dos territórios. Assim, concebe-se que temas como Nacionalismo, identidade, ideologia política, instituições, eleições, e tantas outras temáticas inerentes à política não são simplesmente valores abstratos, ao contrário, constroem-se por e a partir do espaço geográfico. Dividido em três seções, traz na primeira as bases conceituais desse campo de estudo; na segunda seção aparecem os temas da renovação disciplinar como as políticas públicas, as eleições, a gestão de recursos hídricos, a justiça espacial e a cidadania; e a terceira parte, enfim, foi dedicada àquilo que denominamos Hot Spot, ou seja, trata-se dos problemas, conflitos e tensões que marcam determinadas regiões da Terra como a Ásia, a África, a Antártica, a Europa e o Brexit e a América Latina. Além da Geografia, este livro certamente interessará aos estudiosos das áreas de Relações Internacionais, História, Direito, Sociologia e Jornalismo.
Green management and effectiveness of beverage firms in Aba, Abia State
Authors: Aginah Chioma  , Chikwe Goddey Chukwudi  , Njoku Kenneth Chukwudi  , Anyanwu Paschal Chima  , Emeka Nnamdi Ezike
Published: August 2024

The study investigates green management and effectiveness of beverage firms in Aba. The objectives of the study were to evaluate the level of correlation between pollution control and customer satisfaction; pollution control and employee retention; and to examine the level of correlation between waste management and backward integration in beverage firms in Aba. The study was guided by three research objectives, three research questions and three hypotheses. Empirical reviews were used to beef up the study. The researchers employed the survey research design in the research. A five-point Likert Scale structured questionnaire was the major instrument for data collection. The validity of the instrument was done by showing the questionnaire to research experts for their corrections and inputs. Cronbach Alpha statistic was used for obtaining 0.79 as the reliability ratio of the survey instrument. Data analysis was committed to descriptive statistics of mean and standard deviation. Correlation analysis was used to test hypotheses. It was found that there is a significant level of correlation between pollution control and customer satisfaction; there is significant level of correlation between pollution control and employee retention; there is a significant level of correlation between waste management and backward integration in beverage firms in Aba. It was concluded that green management improved the effectiveness of beverage firms in Aba. The study recommended that management of beverage firms should make more efforts to control all forms of pollution in the enterprises for improved customer satisfaction. Management should always work harder to achieve higher degrees of employee retention with the instrumentality of green management. Waste to wealth strategy should be employed by beverage firms for improved business effectiveness.
A study on comparative analysis of zomato and swiggy based on consumer preference in Karaikudi
Authors: M Thiagarajan , M Alagu Amirtha
Published: August 2024

This study presents a comparative analysis of consumer preferences between two leading online food delivery platforms, Zomato and Swiggy. In an era marked by the rapid expansion of e-commerce and the increasing popularity of online food delivery services, understanding consumer behavior and preferences is crucial for businesses to remain competitive. Through a survey-based approach, data was collected from a diverse sample of consumers, encompassing various demographics and geographic locations. The study investigates user demographics, usage patterns, satisfaction levels, preferences, and factors influencing the choice between Zomato and Swiggy. Statistical analysis techniques, including descriptive statistics and correlation analysis, were employed to analyze the data and identify patterns and trends. The findings reveal insights into user satisfaction with different aspects of the platforms, such as user interface, delivery time, food quality, and customer service. Furthermore, the study examines the factors influencing consumers' decisions, such as pricing, promotions, restaurant selection, delivery reliability, and app features. A comparative analysis between Zomato and Swiggy provides valuable insights into the strengths and weaknesses of each platform, aiding in strategic decision-making and service enhancement. The implications of this study extend to both Zomato and Swiggy, as well as other stakeholders in the online food delivery market, offering actionable insights to improve customer satisfaction and gain a competitive edge.
The Application Effect of Predictive Nursing on Cardiopulmonary Rehabilitation of Patients Undergoing Heart Valve Surgery with Extracorporeal Circulation
Authors: Quan Liangyin
Published: August 2024

Objective: To evaluate the application effect of predictive nursing on patients undergoing heart valve surgery with extracorporeal circulation (ECC). Methods: 92 ECC patients admitted to the hospital between July 2021 and July 2023 were selected and grouped by random number table method; the observation group practiced predictive nursing, while the reference group practiced conventional nursing. The cardiopulmonary rehabilitation and other indexes were compared between the groups. Results: The postoperative rehabilitation time of the observation group was shorter than that of the reference group, the treatment compliance was higher than that of the reference group, the cardiopulmonary function indexes were all better than that of the reference group, and the complication rate was lower than that of the reference group (P < 0.05). Conclusion: The implementation of predictive nursing for ECC patients can promote postoperative rehabilitation, improve patients’ treatment compliance, and enhance the cardiopulmonary rehabilitation effect, and nursing safety is high.
Rapamycin Potentiates the Antitumor Effect of 5-Fluorouracil in Colon Cancer by Enhancing Autophagy
Authors: Tian Xiaoming , He Youjun , Hao Tao
Published: August 2024

Objective: To investigate whether the mTOR inhibitor rapamycin can enhance the growth suppression effect of 5-fluorouracil (5-FU) on colon cancer cells. Methods: CCK8 assays were used to examine cell survival. Flow cytometry and Western blotting were employed to detect cell proliferation, apoptosis, and related markers. Results: The combination of rapamycin and 5-FU exhibited greater cytotoxicity in cells compared to rapamycin or 5-FU alone. Notably, cells in the G0/G1 phase increased while cells in the S phase decreased in the combination group, consistent with changes in the levels of Cyclin D1 and PCNA. Rapamycin enhanced 5-FU-induced apoptosis in vitro by inducing caspase-dependent apoptosis, which is Bax/Bcl-2 related. Conclusion: The combination of rapamycin and 5-FU showed a significant synergistic anticancer effect by enhancing autophagy. This study supports that the combination of rapamycin with 5-FU is an effective and feasible approach for colorectal cancer treatment.
The Application of Intelligent Lighting in Thermal Power Plants
Authors: Kang Xiaozhong , Liu Shuangqiang , Hu Guoqing , Huang Haibin
Published: August 2024

With the rapid development of electronic information technology, the Internet of Things (IoT), Internet technology, and modern communication technology, people are demanding higher standards for the building environment. Especially in modern large-scale buildings with high levels of industrialization, lighting systems should also be optimized accordingly. This article explores the application path of intelligent lighting in thermal power plants for reference.
Exploration of Energy-Saving Technologies in Building Electrical System Design
Authors: Zhang Yong
Published: August 2024

Green energy conservation is the mainstream trend in the current development of the construction industry. The application of energy-saving technology in building electrical system design can effectively reduce energy consumption, avoid unnecessary energy consumption, and truly achieve energy conservation and environmental protection. Based on this, the article elaborates on the principles of energy-saving design in building electrical systems, and actively explores the application of energy-saving technologies from different perspectives such as optimizing power supply and distribution system design, adopting high-efficiency energy-saving lighting equipment, applying renewable energy, promoting smart home technology, and improving the efficiency of building electrical equipment.
Clinical Application Analysis of Laparoscopic-Assisted Total Gastrectomy in the Surgical Treatment of Gastric Cancer
Authors: Xue Liang , Shi Zhe , Sun Shugang , Zhao Guodong
Published: August 2024

Objective: To investigate the clinical application effect of laparoscopic-assisted total gastrectomy in the surgical treatment of gastric cancer. Methods: The clinical data of 86 COPD patients included in the study were collected and divided into 43 cases each in Groups A and B using the randomization method, with open total gastrectomy in Group A and laparoscopic-assisted total gastrectomy in Group B. The clinical indexes, pain levels, and complications of patients in the two groups were observed in combination with the indexes. Results: The baseline data of the two groups of patients were not statistically significant (all P > 0.05); the operation time, incision length, first flatulence time, and hospitalization time of patients in Group B were shorter than those in Group A (all P = 0.000); the NRS scores of patients in Group B on the 1st postoperative day and the 2nd postoperative day were significantly lower than those in Group A (t = 23.443, t = 28.784, all P =  0.000); the total complication rate of patients in Group B (1; 2.33%) was significantly lower than that of Group A (9; 20.94%) (χ2 = 7.242, P = 0.007). Conclusion: In the surgical treatment of gastric cancer, laparoscopic-assisted total gastrectomy can promote patients’ recovery, reduce patients’ pain, and lower the probability of complications.
Rekayasa Ulang Sistem Event Ticketing Secara Online Berbasis Website Dengan Penambahan Sistem Streaming On Site pada PT. Cipta Wisata Medika
Authors: Ramadhan Ahmad Syaifudin , Qoiriah Anita
Published: August 2024

Abstrak— Online event ticketing (E-Ticketing) merupakan aktivitas dokumentasi, manajemen, dan penjualan tiket acara yang dilakukan secara online. Aktivitas ini mampu mempermudah segala aktivitas dalam tiketing acara baik dari sisi penyelenggara (organizer) dan pembeli tiket. E-Ticketingpada umumnya dapat dilakukan pada situs web e-ticketing management.Terkait dengan makin berkembangnya sistem e-ticketingmanagement, dalam hal ini, PT. Cipta Wisata Medika dengan salah satu platform e-ticketing management-nya (agendakota). Membutuhkan peningkatan layanan pada sistem yang sudah ada saat ini. Mengingat jenis event yang diadakan saat ini tidak hanya bersifat offline, namun juga online dan hibrid (event yangdiselenggarakan secara online dan offline dalam satu waktu). Sehingga platform e-ticketing management saat ini, membutuhkan fitur streaming on site terintegrasi untuk menyelanggarakan event secara online dan hibrid. Dengan fitur tersebut, akan membuat manajemen dan pelaksanan event onlinedan hibrid menjadi lebih praktis, tanpa harus menggunakan platform terpisah untuk melakukan streaming event tersebut. Dari penelitian ini, diperoleh hasil berupa sistem streaming on site yang terintegrasi dengan platform e-ticketing agendakota. Dengan sistem streaming tersebut terdiri dari dua jenis streaming yaitu satu arah dan video conference. Yang dibangun berdasarkan protokol RTMP – HLS dan SRTP dengan WebRTC API. Kedua jenis sistem streaming tersebut, telah mampu untuk digunakan sebagai layanan streaming event onlinedan hibrid dengan baik, berdasarkan hasil pengujian sistem yang telah dilakukan dalam penelitian ini. Dimana sistem streaming satu arah digunakan untuk event yang tidak membutuhkan interaksi aktif antara peserta dan organizer. Sedangkan untuk kebalikannya, dapat menggunakan sistem streaming video conference.Kata Kunci— Streaming, RTMP, HLS, SRTP, WebRTC, streaming satu arah, streaming video conference
Analisis Perbandingan High Availibility Pada Web Server Menggunakan Orchestration Tool Kubernetes Dan Docker Swarm
Authors: Aldiwidianto Wahyu , Prismana I Gusti Lanang Putra Eka
Published: August 2024

Penelitian ini bertujuan untuk mengetahui penggunaan sumber daya CPU serta efektivitas orchestration tool Docker Swarm dan Microk8s dalam menangani downtime menggunakan teknik failover untuk mencapai high availability, keduanya menjalankan service web server didalam container Docker. Penelitian ini berjenis expremintal design yang mencoba menerapkan sistem high availibility pada web server menggunakan orchestration tool Microk8s dan Docker Swarm. Rancangan high availability server diimplementasikan dengan 3 virtual server yang dijalankan diatas sistem operasi ubuntu. Failover bekerja jika server master mati dan secara otomatis akan digantikan dengan server backup yang telah dikonfigurasi pada perangkat lunak Keepalived. Skema pengujian dilakukan dengan mengirim HTTP request ke server menggunakan perangkat lunak Apache Jmeter, sample request yang dikirim berjumlah 30000 dengan waktu 10 menit, salah satu server akan dimatikan untuk menguji seberapa lama downtime dan penggunaan CPU pada server yang masih aktif. Hasil penelitian menunjukan Docker Swarm lebih baik dalam menangani downtime dengan hasil rata-rata waktu henti mencapai 6,4 detik, sedangkan Microk8s rata-rata downtime 43,7 detik. Dalam penggunaan CPU loadbalancer berjalan dengan cukup baik pada kedua orchestration tool pada saat downtime terjadi. Namun efektivitas penggunaan CPU jauh lebih baik pada Docker Swarm dengan hasil rata-rata CPU usage sebesar 18,202% pada server 1 dan 13,482% pada server 2, sedangkan Micok8s rata-rata penggunaan CPU pada server 1 sebesar 39,2% dan server 2 32,689%. Maka dapat disimpulkan kedua orchestration dapat mengatasi downtime dengan cukup stabil dari keseluruhan pengujian, namun terdapat perbedaan hasil downtime yang cukup signifikan yang dipengaruhi salah satunya oleh penggunaan CPU yang kurang efisien.
Kata Kunci— High Availability, Microk8s, Docker Swarm, Failover, Web Server
Teknik Bagging Pada Algoritma Klasifikasi Decision Tree dan SVM Untuk Klasifikasi SMS Berbahasa Indonesia
Authors: Rosyidi M Ibnu Umar , Rochmawati Naim
Published: August 2024

Abstrak— Perkembangan teknologi di berbagai sektor yang sangat cepat selama satu dekade ini, membuat kita semakin dimudahkan dalam melakukan aktivitas sehari-hari. Dari bertukar surat melalui burung merpati dengan jangkauan terbatas hingga dapat melakukan panggilan video di seluruh dunia dengan selisih waktu yang hampir secara realtime. Pada tahun 2000-an adalah masa dimana mulai ada SMS (Short Message Service). SMS dengan cepat menjadi sarana komunikasi tidak langsung yang populer, situasi ini dimanfaatkan orang tidak bertanggung jawab untuk melakukan kegiatan melanggar hukum seperti penipuan. Untuk mengurangi korban penipuan SMS, perlu untuk menerapkan filter SMS agar tidak semua SMS masuk ke pengguna, salah satu caranya adalah dengan melakukan klasifikasi dan prediksi dari SMS yang masuk apakah SMS tersebut mengandung penipuan atau tidak. Teknik yang biasa dipakai dalam klasifikasi adalah decision tree dan SVM, pada penelitian ini juga akan digunakan teknik ensemble yang dapat meningkatkan kinerja dari algoritma yang digunakan yaitu teknik bagging, data yang digunakan adalah dataset SMS dari penelitan Rahmi dan Wibisono[1]. Penggunaan teknik bagging memiliki pengaruh yang signifikan pada peningkatan nilai akurasi algoritma decision tree dan SVM, decision tree mengalami kenaikan nilai akurasi sebanyak 5% dari 86% menjadi 91% menggunakan data unigram tanpa TF-IDF pada uji 5-fold, algoritma SVM tidak mengalami peningkatan nilai akurasi yang signifikan saat diterapkan teknik bagging.
 
Kata Kunci— Bagging, Klasifikasi, SMS, Decision Tree, SVM, TF-IDF, N-Gram
Ciberdefesa e software power: uma análise exploratória da China
Authors: Moser Nunes Bruno , Felipe David de Oliveira Thays , Victor Lira Brito Renato
Published: August 2024

Como o software power ajuda a compreender a ciberdefesa e a projeção de poder na China? Os avanços tecnológicos e da Internet acrescentaram, nas Relações Internacionais, um novo espaço de disputas e de análise, o Espaço Cibernético, no qual os Estados passaram a traçar estratégias de defesa e expansão de poder que parecem se diferenciar daquelas mais tradicionais, que envolvem a coerção pela força (hard power) ou pelo convencimento (soft power). Há ainda uma terceira forma, que se expressa através de programas, sistemas, aplicativos e informações naquelas estruturas físicas e virtuais que compõem o Espaço Cibernético, o SoftwarePower. Nesse sentido, o objetivo geral deste trabalho é compreender se esta forma de poder é utilizada nos moldes tradicionais de proliferação, ou seja, como uma ferramenta para manifestar os interesses estatais e atingir seus fins soberanos. Para tanto, utilizamos metodologia qualitativa, através de uma análise exploratória de documentos sobre o caso chinês, consistindo a estrutura em um estudo de caso. Dentre os resultados, observa-se que não há uma estratégia clara da política externa chinesa para impor ou convencer outros países sobre estes programas, aplicativos, sistemas e informações oriundos da China. Por outro lado, são identificados interesses, preocupações e questões internas para a defesa chinesa e sua blindagem às influências externas no Espaço Cibernético.
Os impactos da flexibilização do acesso a armas no tráfico transfronteiriço entre o Brasil e o Paraguai
Authors: Somma de Castro Isabelle Christine
Published: August 2024

Este estudo investiga as consequências dos atos normativos de compra e porte de armas de fogo, implementados pela gestão de Jair Messias Bolsonaro(2019-2022), para o mercado ilegal de armas. O fácil acesso às armas legais diminuiu o tráfico transnacional para o Brasil? Para responder a esta pergunta, analisamos dados da Polícia Federal sobre apreensões em dois Estados fronteiriços, Paraná e Mato Grosso do Sul, entre 2013 e 2022. O vizinho Paraguai é um centro conhecido onde os criminosos podem facilmente comprar armas. O país compartilha mais de 1.350 km de fronteira com o Brasil, o que facilita transferências ilegais. Verificamos que a polícia apreendeu menos armas durante os anos de 2019 a 2022 do que nos anos anteriores. Tal achado pode sugerir que os criminosos descobriram outras formas de comprar armas de fogo e que novos mecanismos estão se delineando neste mercado.
Hospital surveillance of respiratory viruses during the COVID-19 pandemic and beyond: contribution to the WHO mosaic framework, Israel, 2020 to 2023
Authors: Gur-Arie Lea , Stein Michal , Sefty Hanna , Fratty Ilana S , Nemet Ital , Kliker Limor , Atari Nofar , Zuckerman Neta S , Rosenberg Alina , Ivgi Heftziba , Golan-Shany Orit , Sorek Nadav , Schwartz-Harari Orna , Bromberg Michal , Keinan-Boker Lital , Mandelboim Michal , Glatman-Freedman Aharona ,   on behalf of the Israeli Respiratory Viruses Hospital Laboratory Network (IRVHLN)
Published: August 2024

Background

A new respiratory virus surveillance platform, based on nationwide hospital laboratory data, was established in Israel during the COVID-19 pandemic.

Aim

We aimed to evaluate the performance of this platform with respect to the detection of influenza and respiratory syncytial virus (RSV) from week 36 in 2020 to week 15 in 2023, and how it fits with the World Health Organization (WHO) mosaic surveillance framework.

Methods

Data of respiratory samples from hospitalised patients sent for laboratory confirmation of influenza virus or RSV from 25 general hospital laboratories nationwide were collected. We analysed the weekly number and percentage of samples positive for influenza virus or RSV vis-à-vis SARS-CoV-2 activity and compared data from the new surveillance platform with existing surveillance platforms. Using data in the new surveillance platform, we analysed early stages of a 2021 out-of-season RSV outbreak and evaluated the capabilities of the new surveillance system with respect to objectives and domains of the WHO mosaic framework.

Results

The new hospital-laboratory surveillance platform captured the activity of influenza virus and RSV, provided crucial data when outpatient sentinel surveillance was not operational and supported an out-of-season RSV outbreak investigation. The new surveillance platform fulfilled important objectives in all three domains of the mosaic framework and could serve for gathering additional information to fulfil more domain objectives.

Conclusion

The new hospital laboratory surveillance platform provided essential data during the COVID-19 pandemic and beyond, fulfilled important domain objectives of the mosaic framework and could be adapted for the surveillance of other viruses.
Is hamstring muscle shortness responsible for low back pain in healthcare professionals?
Authors: Mirzazada Javad , Mirzazada Elif
Published: August 2024

Background/Aim: Low back pain (LBP) is a highly prevalent pathology affecting more than half of our population. The lumbar region inherently possesses a complex structure; therefore, dozens of causes for the clinical presentation of acute/chronic pain are present. We focused on the impact of hamstring shortness on LBP in healthcare workers/professionals who need to keep medical records and perform invasive procedures while traveling overwhelming distances in relatively small workplaces.
Methods: Our research was designed as a cross-sectional study and was conducted at Beykent University Hospital from March to April 2022. Sixty-two otherwise healthy healthcare workers/professionals aged 25–45 (both male and female) volunteered. Two equal groups with and without LBP were created. Oswestry disability index, Roland–Morris score, Quebec LBP questionnaire, Visual Analog Scale (VAS), active/passive knee extension, sit and reach, and forward bending tests were performed in each group. The collected data were statistically analyzed (confidence interval [CI]=20%; P<0.05).
Results: Active/passive knee extension, sit and reach, and toe touch tests were significantly related to Roland–Morris, Quebec, and Oswestry Disability Index questionnaires; thus hamstring muscle shortness was significantly related to chronic low back pain (P<0.05). Short hamstring muscle length could accurately reflect the lower test scores obtained by the female participants.
Conclusion: Hamstring muscle shortness could explain a significant proportion of low back pain in healthcare professionals.
Impact of Rear Slope Variation on Rubble Mound Breakwater Stability Under Seismic Loading
Authors: Morabit Abdelmajid , El Ghoulbzouri Abdelouafi
Published: August 2024

This study aims to enhance the seismic stability of rubble mound breakwaters, crucial maritime structures, by examining how variations in the rear slope angle affect their response to seismic loads. Utilizing the Plaxis 2D software, a finite element method was employed to simulate the behavior of a conventional rubble mound breakwater under different seismic conditions. The analysis considered three different rear slope angles and subjected each to various seismic loads characterized by differing amplitudes and frequencies. Our findings indicate that the rear slope inclination significantly influences the seismic response of the breakwaters, notably affecting the displacements and deformations within the structure. The most optimal angle of inclination was identified, which minimized the seismic-induced deformations, thereby potentially improving the structural integrity and longevity of these maritime defenses. This investigation not only provides valuable insights into the design of more resilient maritime structures but also introduces an approach to optimize breakwater design for better performance under seismic conditions, marking a notable improvement in the field of maritime engineering. Doi: 10.28991/CEJ-SP2024-010-08 Full Text: PDF
THE POSSIBILITY OF OBTAINING AND USING CRIMINALLY SIGNIFICANT INFORMATION FROM FILE METADATA IN THE DETECTION AND INVESTIGATION OF CRIMES
Authors: Ryasov Aleksandr
Published: August 2024

Modern technologies and the digitalization of society have led to the fact that most of the information in the world is stored and transmitted electronically. This circumstance opens up new opportunities for law enforcement agencies in the detection and investigation of crimes. In today's world, where technology plays a key role in society, digital footprints are becoming an important element in crime investigation.
Everyone has already got used to the fact that the main object of computer expertise in the field of computer information is the contents of files. However, such an important area as the study of file metadata remains underestimated in the investigation process. Metadata is an integral part of mod-ern crime investigation, providing investigators with valuable data for analysis and helping to restore the chronology of events and actions of persons associated with the crime. In the field of digital fo-rensics, special attention should be paid to the study and analysis of electronic traces that can be found in metadata.
The issues of using file metadata have been touched upon in one way or another by many scien-tists, such as L.A. Buraeva [1], V.A. Gauzhaeva [2], R.R. Kardanov [3], Yu.M. Usoltsev [4], A.S. Arutyunov [5] and others. However, these authors made only an attempt to draw attention to the use of metadata in the investigation of crimes.
Metadata may contain information about the time the file was created, its author, location, and other data that can be used in proving criminal cases.
Metadata in the commission of crimes related to the use of information and telecommunication technologies can be compared with micro-objects in the commission of traditional crimes. Both are invisible traces, which are not so easy to destroy and to which few criminals pay attention. At the same time, they can provide significant assistance to the investigation in uncovering and investigat-ing crimes.
This article attempts to draw the attention of the scientific world and employees involved in the preliminary investigation of crimes to the problems and possibilities of using metadata in the process of disclosure and investigation of crimes.
LEGAL AND ORGANIZATIONAL BASES OF POLICE ASSISTANCE TO MINORS (BASED ON MATERIALS FROM THE REPUBLIC OF CRIMEA)
Authors: Chelpanova Marina
Published: August 2024

The relevance of the topic lies in the fact that the protection of minors is an important and priority ar-ea of activity of the system of state bodies, including the Ministry of Internal Affairs of Russia, both on the scale of the Russian Federation and in its individual regions.
The analysis of statistical data allows us to state the positive results of the organization and implementation of purposeful and comprehensive work of juvenile affairs units, namely, assistance to minors, updating the forms and methods of such activities.
Means of implementing the functions of the mechanism for realizing the interests of the rural population
Authors: Ulez'ko Andrey , Reymer Valeriy
Published: August 2024

In the article "The composition of the mechanism for realizing the interests of the rural population", this mechanism was considered as a set of structural, functional and supporting elements aimed at creating a favorable environment that ensures full satisfaction of the needs (realization of interests) of the rural population. It was concluded that each structural element (subject) has its own set of tools and methods for solving individual functional tasks, in accordance with the functions assigned to them, while the entire set of identified functions is implemented at the level of individuals and households reflecting the composition of the rural population. This article substantiates the tools for the implementation of these functions by such types of structural elements as the state, regions, municipalities, business entities, rural settlements, public organizations, social communities and groups. Due to the constancy of the structural, functional and supporting elements of the mechanism for realizing the economic interests of the rural population and the stability of its structure, it is concluded that the improvement of the mechanism will be connected, first of all, with the development of means for implementing its functions and improving the quality of coordination of interactions of its structural elements, as well as with the formation of an information base characterizing the conditions and the results of the realization of the economic interests of the rural population.
Aplikasi Sistem Penomoran Surat Otomatis Berbasis Website Pada Perumda Tirtanadi Aceh Utara
Authors: Perolihin Manurung Ericky Benna , Rizal Reyhan Achmad
Published: August 2024

Perumda tirtanadi aceh utara adalah salah satu instansi perusahaan air minum di kabupaten aceh utara. Perumda tirtanadi aceh utara sudah banyak memanfaatkan dunia teknologi dalam menyelesaikan pekerjaan sehari-sehari di kantor tersebut.  Namun untuk pengambilan nomor surat perumda tirtanadi aceh utara masih menggunakan sistem manual yaitu memanfaatkan buku agenda dalam pengambilan nomor surat sehingga hal ini membuat kinerjanya kurang efektif. Sehigga penulis tertarik melakukan penelitian didalam kantor tersebut. Pada saat melakukan pengumpulan data-data surat didalam kantor pusat perumda tirtanadi aceh utara melakukan 3 metode yaitu mengumpulkan dokumen, interview, dan melakukan observasi untuk mendapatkan hasil. Hal ini membuat penulis memanfaat perancangan sistem yang menggunakan DFD (Data Flow Diagram), ERD (Entity Relationship Diagram), serta flowchart. Selanjutnya dalam membuat sistem penulis memanfaatkan Sublime Text, MySQL Database Xampp, back-endnya menggunakan PHP biasa dan untuk tampilan website menggunakan Boostrapp 5. Penelitian ini diharapkan dapat mengahasilkan sebuah sebuah sistem penomoran surat masuk dan surat keluar secara otomatis berbasis web yang sangat bermanfaat untuk pegawai perumda tirtanadi aceh utara.
Table of Contents
Authors: Peterson Lesley
Published: August 2024

This is the Table of Contents for JJS 6.2, published August 2024.
Ações de educação em saúde do trabalhador para prevenção de doenças ocupacionais: Uma atividade extensionista
Authors: Pôrto Arthur Henrique Resende , Alexandre André Ribeiro , Santos Sérgio Valverde Marques dos
Published: August 2024

As doenças ocupacionais caracterizam-se pelos males que são produzidos ou desencadeados pelo exercício profissional peculiar à determinada atividade. Mesmo presentes nos ambientes laborais, nem sempre esses trabalhadores conseguem identificar os fatores de risco ou, até mesmo, as doenças a que estão expostos. Nesse sentido, este trabalho tem como objetivo relatar a experiência de um grupo de pesquisadores durante a execução de atividades extensionistas por meio de ações de educação em saúde do trabalhador para prevenção das doenças ocupacionais. Para isso, foi criada uma conta do Instagram, onde foram compartilhadas periodicamente postagens informativas e notícias acerca de temas relacionados à Medicina do Trabalho. Além disso, foram ofertadas, por meio das Unidades de Estratégias Saúde da Família (ESFs), palestras didáticas e interativas à população trabalhadora, em conjunto com a distribuição de folders, abordando as principais doenças ocupacionais. Ao final da execução do projeto, o perfil do Instagram alcançou o número de 717 seguidores. Foram realizadas 33 publicações, que foram repostadas nos stories e alcançaram um total de 7544 visualizações. Além disso, foram ministradas palestras em sala de espera de 24 ESFs, alcançando um total de 210 pessoas. Com isso, foi possível considerar que a execução do projeto de extensão foi exitosa, pois contribuiu para a divulgação e ampliação do conhecimento dos trabalhadores acerca das doenças ocupacionais decorrentes do trabalho.
Divulgação científica do projeto “Conservação da Biodiversidade: Tubarões na Praia” por meio das redes sociais
Authors: Medeiros Jade , Mafaldo Henrique , Araújo Marcus Vinicius Gonçalves , Silva João Paulo Capretz Batista da
Published: August 2024

Os tubarões e as raias são animais que têm sido gradativamente impactados pelas ações antrópicas. Uma das atividades que tem impactado grandemente esse grupo de peixes é a pesca indiscriminada, como consequência de uma fiscalização ambiental incipiente, da aplicação de nomes comuns a uma série de espécies distintas e o processamento de animais (e.g. decapitação) ainda embarcados, dificultando assim a sua identificação. Aliados a isso, os elasmobrânquios têm características biológicas e reprodutivas complexas que os tornam vulneráveis à atividade antrópica e a sobrepesca, como ciclo de vida longo, maturação sexual tardia e baixa fecundidade. Nesse sentido, nossas premissas seriam de que a conservação efetiva dos elasmobrânquios envolve a sociedade como um todo e seja eficaz no monitoramento adequado de espécies vulneráveis e ameaçadas de extinção. Dessa maneira, o presente projeto teve como objetivo a integração entre Universidade Federal da Paraíba (UFPB) e a sociedade para a disseminação de conhecimentos associados à diversidade de espécies de elasmobrânquios da costa da Paraíba, de seus aspectos biológicos e graus de vulnerabilidade, de modo a promover a sua conservação. Nossa página na plataforma Instagram chegou a cerca de 1500 seguidores e nossas publicações obtiveram individualmente uma média de 150 curtidas e alcançaram aproximadamente 600 contas. O engajamento do público foi significativo e promoveu, além da troca de conhecimentos, uma nova percepção e interesse muito maior no grupo.
PREVENÇÃO E RISCOS DA INFECÇÃO URINÁRIA NA GESTAÇÃO, NO CENTRO DE SAÚDE TURU II
Authors: Souza Adrielly Reis , Costa Alana Mayara Santos , Sousa Alexandra Moraes Costa de , Siqueira Betânia Nunes , Garcia Brenda Maryelle Damasceno , Siqueira Carla Danielle Silva Xerez , Chagas Felipe Eistein Campos , Lima Gabriel Nava
Published: August 2024

O projeto de extensão foi idealizado a partir da análise de como era realizada a orientação das gestantes que faziam o acompanhamento pré-natal Centro de Saúde do Turu II. Durante a observação in loco, e em conversas com as gestantes antes e pós-realização das consultas de pré-natal, identificamos uma lacuna no processo de orientação das gestantes no que se refia aos cuidados durante a gestação. Em particular, notamos que muitas gestantes careciam de conhecimento sobre os problemas e riscos associados à infecção urinária durante a gravidez, bem como das medidas preventivas necessárias. Essa falta de conhecimento representa desafio considerável para a promoção da saúde materna dentro do território onde se encontra o Centro de Saúde do Turu II.

Essa constatação motivou a implementação de uma estratégia de intervenção direcionada às gestantes do Centro de Saúde do Turu II buscando fornecer informações abrangentes sobre a infecção urinária durante a gestação, destacando os riscos associados a essa condição, e as medidas de prevenção eficazes. Isso implicou na promoção de conhecimentos e conscientização das gestantes a acerca dos aspectos clínicos, epidemiológicos e preventivos relacionados à infecção urinária gestacional, com o intuito de empoderar as gestantes para tomar decisões informadas sobre sua saúde durante a gravidez.

Somado aos ganhos individuais para as gestantes, o Projeto de Extensão é fundamentado no entendimento de que a conscientização pode promover práticas de prevenção simples, como o consumo adequado de água e a higiene pessoal, que têm o potencial de reduzir significativamente o risco de IU durante a gravidez, minimizando, assim, o ônus financeiro que recai sobre os sistemas de saúde (Jones et al., 2019). A conscientização, de acordo com estudos de saúde comportamental, pode não apenas prevenir complicações potencialmente graves, mas também melhorar a qualidade de vida das futuras mães, proporcionando uma experiência de gravidez mais tranquila e confortável (Brown; Smith, 2018).
DIABETES MELLITUS NA GESTAÇÃO RISCO PARA GESTANTE E FETO
Authors: Lopes Anna Lúcia Araújo Corrêa , Ferreira Alzira de Maria Costa , Pereira Janiele da Silva , Guimarães Jorziane Mota , Batalha Manuel , Luna Rayssa de Sousa , Lima Gabriel Nava
Published: August 2024

O projeto de extensão detalhado neste relatório tem como temática a diabetes gestacional, mais especificamente, os riscos que o desenvolvimento da diabetes mellitus na gestação pode trazer para a gestante e feto.

O projeto foi desenvolvido por acadêmicos do primeiro período do curso de Medicina da Faculdade EDUFOR, sob orientação do Prof. Dr. Gabriel Nava Lima, na disciplina de Prática de Extensão Universitária I, e implementado no Hospital Municipal e Maternidade de São José de Ribamar -MA.
DESAFIOS FREQUENTES NO PERÍODO DE ALEITAMENTO MATERNO E COMO SUPERÁ-LOS
Authors: Rocha Helmo de Oliveira , Saldanha Carolina Simões Castro Kraiesky , Branco Paulo Felipe Carneiro Castelo , Reis Thais Milena Guimarães , Oliveira Antônio Everardo de , Sardinha Vitor de Lima Vaz , Gomes Igor Nascimento , Lopes Elias Gustavo Linhares , Lima Gabriel Nava
Published: August 2024

As adversidades enfrentadas durante a amamentação constituem um dos maiores obstáculos encarados por essas gestantes. As mulheres no período gestacional e de leitamento materno dos bairros Turu, Parque Vitória e Novo Cohatrac, que são atendidas na Unidade Básica de Saúde Djalma Marques, enfrentam problemas relacionados à amamentação, alterações hormonais, privação do sono e pressões sociais. Frente essa realidade constatada, este projeto de extensão identificou que as adversidades enfrentadas
durante a amamentação constituem um dos maiores obstáculos encarados por essas gestantes, motivo pelo qual deliberou-se que na estruturação do Projeto de Extensão seriam abordados os aspectos referentes à importância do leite materno e seus benefícios para mãe e bebê, à falta de informação sobre a prática da lactação e aos problemas de cunho fisiológicos que ocorrem nesse período, como a demora na descida do leite, mamilos doloridos e/ou machucados, mamilo plano ou invertido, ingurgitamento mamário ou “leite empedrado”, mastite, bloqueio de ductos lactíferos e sensação de “pouco leite”.