bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Influencing Factors on Hospitalization Expenses of Patients with Breast Malignant Tumor Undergoing Surgery: Based on the Neural Network and Support Vector Machine
Authors: Zhang Jing , Sun Lin
Published: November 2021

Objective. Analyze the influencing factors of hospitalization expenses of breast cancer patients in a tertiary hospital in Chengdu and provide a basis and suggestion for controlling the unreasonable increase of medical expenses. Methods. The first pages of all inpatient medical records of patients with breast malignant tumor from 2017 to 2020 were extracted, and the descriptive analysis, single-factor analysis, and multifactor analysis were conducted by using the statistical method and data mining method to explore the influencing factors of hospitalization expenses. Results. In 2017–2020, the average hospitalization cost and the average surgical treatment cost increased year by year, and the number of operations, actual hospitalization days, and CCI were the important influencing factors. Conclusion. It is suggested to strengthen the supervision of medical rationality and eliminate the waste of medical resources; and we should improve the efficiency of diagnosis and treatment services, so as to shorten the actual length of hospitalization; at the same time, the combination of DRG grouping and fine management can be used to control the hospitalization expenses.
Analysis of Curative Effect and Prognostic Factors of Radiotherapy for Esophageal Cancer Based on the CNN
Authors: Zhao Yunhui , Xu Junkai , Chen Qisong
Published: November 2021

An esophageal cancer intelligent diagnosis system is developed to improve the recognition rate of esophageal cancer image diagnosis and the efficiency of physicians, as well as to improve the level of esophageal cancer image diagnosis in primary care institutions. In this paper, by collecting medical images related to esophageal cancer over the years, we establish an intelligent diagnosis system based on the convolutional neural network for esophageal cancer images through the steps of data annotation, image preprocessing, data enhancement, and deep learning to assist doctors in intelligent diagnosis. The convolutional neural network-based esophageal cancer image intelligent diagnosis system has been successfully applied in hospitals and widely praised by frontline doctors. This system is beneficial for primary care physicians to improve the overall accuracy of esophageal cancer diagnosis and reduce the risk of death of esophageal cancer patients. We also analyze that the efficacy of radiation therapy for esophageal cancer can be influenced by many factors, and clinical attention should be paid to grasp the relevant factors in order to improve the final treatment effect and prognosis of patients.
Some Bond Incident Degree Indices of (Molecular) Graphs with Fixed Order and Number of Cut Vertices
Authors: Albalahi Abeer M. , Ali Akbar , Zafar Tayyba , Mohammed Wael W.
Published: November 2021

A bond incident degree (BID) index of a graph

G

is defined as

∑

u
v
∈
E

G

f

d

G

u

,

d

G

v

, where

d

G

w

denotes the degree of a vertex

w

of

G

,

E

G

is the edge set of

G

, and

f

is a real-valued symmetric function. The choice

f

d

G

u

,

d

G

v

=

a

d

G

u

+

a

d

G

v

in the aforementioned formula gives the variable sum exdeg index

SEI

a

, where

a
≠
1

is any positive real number. A cut vertex of a graph

G

is a vertex whose removal results in a graph with more components than

G

has. A graph of maximum degree at most 4 is known as a molecular graph. Denote by

V

n
,
k

the class of all

n

-vertex graphs with

k
≥
1

cut vertices and containing at least one cycle. Recently, Du and Sun [AIMS Mathematics, vol. 6, pp. 607–622, 2021] characterized the graphs having the maximum value of

SEI

a

from the set

V
n
k

for

a
>
1

. In the present paper, we not only characterize the graphs with the minimum value of

SEI

a

from the set

V
n
k

for

a
>
1

, but we also solve a more general problem concerning a special type of BID indices. As the obtained extremal graphs are molecular graphs, they remain extremal if one considers the class of all

n

-vertex molecular graphs with

k
≥
1

cut vertices and containing at least one cycle.
Follicular Dendritic Cell Sarcoma of the Thyroid Gland in a Patient with Preexisting Hashimoto’s Thyroiditis: A Rare Case Report with a Literature Review
Authors: Seyed-alagheband Seyed-ahmad , Shahmoradi Mohammad-kazem , Adeli Omid-Ali , Shamsi Tahereh , Sohooli Maryam , Shekouhi Ramin
Published: November 2021

Thyroid follicular dendritic cell sarcoma (FDCS) is an extremely rare malignancy that originates from follicular dendritic cells of the thyroid germinal centers. To the best of our knowledge, there are only 4 reported cases of thyroid FDCS in the English literature. Herein, we present the fifth case of FDCS of the thyroid gland. A 63-year-old woman presented with a painless midline neck mass, enlarging for the last 4 months. Physical examination revealed a 6-cm nonmobile, firm, multinodular thyroid mass with palpable cervical lymphadenopathy. Due to high suspicion for thyroid malignancy, the patient underwent total thyroidectomy with bilateral modified radical neck dissection. Histologic evaluations revealed sheets of storiform eosinophilic tumoral cells with prominent nucleoli containing multinucleated giant cells, and subsequent immunohistochemistry showed immunoreactivity for CD4, CD21, CD35, CD45 (LCA), and CD68. The patient was started on 6 cycles of doxorubicin, ifosfamide, and radiotherapy. She has had monthly thyroid ultrasonography and contrast-enhanced thoracoabdominal CT scan every 3 months for detecting potential recurrence and/or metastasis screening. Fortunately, 8 months after the operation, the patient is alive without any signs of local or distant metastasis.
Endometriumkarzinom: Anthrazyklinfreies Therapieregime zeigt weniger Toxizitäten und bessere gesundheitsbezogenen Lebensqualität
Authors: Szeterlak Nina
Published: November 2021

Purpose: Limitations of the paclitaxel-doxorubicin-cisplatin (TAP) regimen in the treatment of endometrial cancer include tolerability and cumbersome scheduling. The Gynecologic Oncology Group studied carboplatin plus paclitaxel (TC) as a noninferior alternative to TAP. Methods: GOG0209 was a phase III, randomized, noninferiority, open-label trial. Inclusion criteria were stage III, stage IV, and recurrent endometrial cancers; performance status 0–2; and adequate renal, hepatic, and marrow function. Prior radiotherapy and/or hormonal therapy were permitted, but chemotherapy, including radiosensitization, was not. Patients were treated with doxorubicin 45 mg/m2 and cisplatin 50 mg/m2 (day 1), followed by paclitaxel 160 mg/m2 (day 2) with granulocyte colony-stimulating factor or paclitaxel 175 mg/m2 and carboplatin area under the curve 6 (day 1) every 21 days for seven cycles. The primary endpoint was overall survival (OS; modified intention to treat). Progression-free survival (PFS), health-related quality of life (HRQoL), and toxicity were secondary endpoints. Results: From 2003 to 2009, 1,381 women were enrolled. Noninferiority of TC to TAP was concluded for OS (median, 37 v 41 months, respectively; hazard ratio [HR], 1.002; 90% CI, 0.9 to 1.12), and PFS (median, 13 v 14 months; HR, 1.032; 90% CI, 0.93 to 1.15). Neutropenic fever was reported in 7% of patients receiving TAP and 6% of those receiving TC. Grade > 2 sensory neuropathy was recorded in 26% of patients receiving TAP and 20% receiving TC (P = .40). More grade ≥ 3 thrombocytopenia (23% v 12%), vomiting (7% v 4%), diarrhea (6% v 2%), and metabolic (14% v 8%) toxicities were reported with TAP. Neutropenia (52% v 80%) was more common with TC. Small HRQoL differences favored TC. Conclusion: With demonstrated noninferiority to TAP, TC is the global first-line standard for advanced endometrial cancer. Trial registration: ClinicalTrials.gov NCT00063999.
A vaia viva de Augusto de Campos
Authors: Rost Isis Diana
Published: November 2021

O enfoque deste ensaio é comentar MONUMENTO À VAIA, escrito em 1972 para compor a Navilouca, almanaque organizado por Torquato Neto e Waly Salomão. É composto por VIVA VAIA – Magnum Opus do poeta concreto Augusto de Campos, inspirado na vaia recebida por Caetano Veloso no III Festival Internacional da Canção, em 1968. Foram utilizadas principalmente as contribuições de CAMPOS (1993) e VELOSO (1997).
Literatura e música: um encontro possível na escola
Authors: Menezes Juliana Alves , Vinha Everton Luis Paulino
Published: November 2021

O objetivo do artigo é apresentar uma prática do ensino de literatura, no Ensino Fundamental II, em duas turmas de 6º anos de uma escola particular da cidade de Maringá, noroeste do Paraná. Os resultados revelaram que é possível atender ao gosto do aluno e levá-los a se aproximarem dos textos literários, porém ao docente cabe o papel de compreender o seu alunado como leitores contemporâneos
Da avalanche lírica em redes sociais: remediações poéticas em Snow, de Shelley Jackson
Authors: Pereira Vinícius Carvalho
Published: November 2021

A popularização de redes sociais tem culminado num consumo massivo de dados, textos e fotos, majoritariamente destituídos de qualquer pretensão artística. No entanto, há perfis nas redes que se valem dessa mídia para constituir propostas de força crítica e lírica. Neste artigo, analisamos um projeto de criação de tal natureza: o poema em prosa Snow, de Shelley Jackson, composto por fotos de palavras escritas na neve, postadas ao longo de anos por uma conta no Instagram. Entre outras questões, interessa ao presente estudo discutir as remediações poéticas que constituem essa obra no percurso criativo da palavra à neve, à foto, à rede, bem como os impactos que essa materialidade estratificada traz a Snow em termos de sua complexa temporalidade.
Sarau Virtual: Conceitos Spinozianos e Deleuzeanos no Ciberespaço como Potência Criativa e Afetiva na Pandemia de Covid-19
Authors: OLIVEIRA UILLIAN TRINDADE
Published: November 2021

Este artigo suscita reflexões a respeito da experiência de criação e exposição de trabalhos artísticos por meio do projeto de extensão “Sarau Virtual Mande Notícias”, realizado em 2020, durante a pandemia de Covid-19. As relações que se estabeleceram durante tal evento são expostas e analisadas sob a luz dos conceitos spinozianos conatus, perceptos e afectos e pelos conceitos deleuzeanos rizoma e territórios. Também são mostrados os processos de criação artística no mundo concreto a serem transpostos para o mundo virtual, o ciberespaço, como potência criativa e expositiva de afetar e ser afetado. Para tratar tal assunto, dialogamos com os seguintes autores: Deleuze e Guattari (2009), Domingues (2004), Lévy (2009), McLuhan (1964); Spinoza (2009), dentre outros. O texto busca mostrar as novas interfaces de criação e exposição de trabalhos artísticos no momento pandêmico, como forma de o ser humano se desterritorializar, criar e ressignificar sua existência por meio de atos potentes em fluxos constantes.
First record of the genus Lodosocoris Ahmad & Afzal (Hemiptera: Heteroptera: Pentatomidae: Halyini) from India with description of a new species
Authors: SALINI S. , RABBANI M. K. , AMALA U. , MAHENDIRAN G.
Published: November 2021

The genus Lodosocoris Ahmad & Afzal, 1986 (Hemiptera: Heteroptera: Pentatomidae: Pentatominae: Halyini) is recorded for the first time from India. Prior to this publication, the genus was monotypic so far, containing only Lodosocoris azhari Ahmad & Afzal, 1986 from Pakistan. Herein, the genus Lodosocoris is redescribed along with the description of Lodosocoris santhae sp. nov., based on specimens from Arunachal Pradesh, a region in northeastern India. Lodosocoris santhae sp. nov is described and illustrated based on male and female genitalia. The diagnostic characters of the new species are compared with L. azhari.
The literature/science boundary in sociological articles: Using fiction to discover patterns in co-authorship, author gender, and citation rank
Authors: Hladík Radim , Digre Neal
Published: November 2021

Sociology has been described as a ‘third culture’ between science and literature. The distinctions between different orientations in sociological writing have been studied primarily through their non-textual manifestations (publication genres or venues, methodologies used, scientometric indicators, etc.). Our knowledge of how the science–literature boundary relates to the rhetorical composition of sociological texts therefore remains limited. We mixed a bespoke corpus of Czech sociological articles with a corpus of Czech short fiction to straightforwardly account for the relationship between sociology and literature. Unsupervised classification based on the distribution of most frequent verbs yielded two categories of sociological articles. Each cluster exhibited significant association with non-textual variables. Articles less similar to literature were associated with higher rates of co-authorship, citation counts, and number of women as first authors. Both clusters also displayed clear semantic differences. The signal from literary works increased variance in the textual feature space and subsequent pseudo-experimental validation confirmed its indispensability for the discovery of the association between the rhetorical pattern of verbs usage and non-textual variables related to sociological articles.
Critical Co-Constructed Autoethnography: Reflections of a Collaborative Teaching Experience of Two Black Women in Higher Education
Authors: Warren-Gordon Kiesha , Jackson-Brown Angela
Published: November 2021

Within this paper, two Black women teaching at a predominantly white institution of higher education utilize critical co-constructed autoethnography to reflect on their experiences of using a Womanist approach to co-teach two capstone courses during a global pandemic. Womanism is an epistemology focused on the experiences and concerns of Black women. Using this collaborative inquiry technique, we explore how forms of systemic racism within predominantly white institutions affects our ability to teach and grow as researcher in our specific fields. Critical co-constructed autoethnography is a methodology steeped in critical theory, critical pedagogy, and critical race theory that reflects the tempo, uncertainty, and complexity of research relationships that creates spaces for collaborating researchers to work across differences. We conclude this paper by highlighting the value of using co-constructed autoethnography as a method of articulating the voices of those who have traditionally been underrepresented in academia. This method also allows for the congruency of voices, which is a limitation within traditional autoethnography.
A model-based approach to social ontology
Authors: Sarkia Matti
Published: November 2021

This paper argues for theoretical modeling and model-construction as central (but not necessarily the only) types of activities that philosophers of social ontology (in the analytic tradition) engage in. This claim is defended through a detailed case study and revisionary interpretation of Raimo Tuomela’s account of the we-perspective. My interpretation is grounded in Ronald Giere’s account of scientific models, and argued to be compatible with, but less demanding than Tuomela’s own description of his account as a philosophical theory of the social world. My approach is also suggested to be applicable to many (but not necessarily all) other methodologically naturalist accounts of collective intentionality and social ontology.
Significance as component of meaning in career narratives of unemployed graduates
Authors: van Lill Rinet , Bakker Terri M
Published: November 2021

Youth unemployment is a continuing concern in South Africa, and, in the context of growing economic volatility, an increasing number of young adult graduates will find themselves without work. Given the negative effect of unemployment on psychological well-being, research is required to enhance insight into how unemployed graduates can negotiate times of unemployment. Although multiple studies have investigated the influence of unemployment on hedonic well-being, less research is available on how eudaimonic well-being is impacted by unemployment. Significance is a component of meaning, and refers to a sense of mattering in one’s social context. The aim of the current study was to explore how young adult graduates experience a sense of significance during unemployment. Semi-structured interviews were conducted to gain insights into participants’ career narrative, which were then analysed to find meaning plots that relate to significance. The results showed that threads of significance are present throughout the participant’s career narratives, and that the lack of significance during unemployment resulted in great distress, but also a need to restore significance. The value of the study lies in uncovering significance as an important resource during unemployment, which could be a focal point to address in psychological interventions.
Bereavement and educational outcomes in children and young people: A systematic review
Authors: Elsner Tahli L. , Krysinska Karolina , Andriessen Karl
Published: November 2021

Experiencing bereavement due to the death of a close person is rife in the lives of young people. This review aimed to investigate how bereavement affects educational outcomes of students at various educational levels and what factors may be involved in moderating these outcomes. The systemic review was conducted according to the PRISMA guidelines with searches of peer-reviewed literature in Embase, Emcare, Medline, PsycINFO and Scopus. Twenty-two studies (17 quantitative and 5 qualitative) were included. In general, bereavement can constitute a barrier to educational achievement in young people compromising academic performance, and educational engagement and attainment. Several factors can place young people at greater risk of experiencing this disadvantage and further research into these mechanisms and interventions to mitigate short- and long-term consequences, especially among high-risk groups, is warranted.
The impact of trans-arterial embolization on the result of chemoradiotherapy in oral cavity cancer
Authors: Nguyen Van Dang , Le Van Quang , Nguyen Thi Thu Nhung , Bui Van Giang , Ta Van To
Published: November 2021

Objectives: Evaluation of the hemostatic effect of trans-arterial embolization on patients with advanced oral cavity cancer who had bleeding complications while undergoing definitive concurrent chemoradiotherapy (CCRT). Additionally, assess the effect of trans-arterial embolization on treatment response following concurrent chemoradiotherapy, as well as overall survival (OS) and progression-free survival (PFS) in the group of patients following the intervention.

Method: From September 2018–June 2021, a retrospective descriptive study was conducted on 16 patients with inoperable, locally advanced oral cavity cancer who received definitive concurrent chemoradiotherapy, experienced acute bleeding complications, and received selective intravascular intervention with various embolization materials at Vietnam National Cancer Hospital.

Results: After selective embolization, 16/16 patients ceased bleeding; 1 patient re-bled for the second time after 3 weeks. The average duration of chemoradiotherapy interruption due to intervention was 6.7 days. After CCRT, 15/16 (93.75%) patients achieved a response, with 9/16 (56.25%) patients achieving a complete response. The median OS was 14 months (range, 3–26 months), and the median PFS was 10 months (range, 3–20 months). There were no significant complications, particularly neurological side effects.

ConclusionsTumor bleeding is a common and serious complication of CCRT treatment in patients with locally advanced oral cavity cancer. Embolization is a safe and effective method of controlling acute bleeding that has no adverse effect on the outcome of definitive concurrent chemoradiotherapy.
Delta neutrophil index levels can be a good indicator to predict patients with chronic rhinosinusitis who need surgery
Authors: Son Sumin , An Hong Geun , Park Joong Su , Kim Seung Ho , In Seung Min , Kim Jong-Yeup , Lee Suehyun , Cha Jaehun , Lee Jong Wook , Lee Ki-Il
Published: November 2021

Objectives

Predicting the need for surgical treatment among patients with chronic rhinosinusitis (CRS) is challenging. The delta neutrophil index (DNI) has been proposed as a useful laboratory marker of immature granulocytes, which indicates infection or severe inflammation in several diseases. This study evaluated DNI as an early predictor of the need for surgery in patients with CRS.

Methods

A total of 117 patients diagnosed with CRS were enrolled in this retrospective and observational study. Medical records, including symptoms data, WBC count, ESR level, LUC count, Lund-Mackay scores, and DNI, were reviewed. The receiver operating characteristic (ROC) curves were analyzed to determine the optimal cut-off values for predicting surgery.

Results

Among 117 patients, 49 patients (41.9%) needed surgical intervention. The areas under the WBC, ESR, LUC, and DNI ROC curves were .571, .600, .592, and .782, respectively. The optimal cut-off value of DNI to predict surgery was .9%. The prognostic precision of DNI showed that the sensitivity was 59.2% and the specificity was 98.5%. In the analysis of risk factors, DNI levels were significantly associated with surgical intervention (odds ratio, 2.22; 95% confidence interval, 1.48-3.34; P < .01).

Conclusions

The level of DNI, which reflects the severity of the disease, may be a useful predictor for determining the need for surgical intervention in patients with CRS. This is the first literature to verify the role of DNI in upper airway disease.
Clinical diagnostic utility of ultrasound-guided fine needle aspiration biopsy in parotid masses
Authors: Hamour Amr F. , O’Connell Dan , Biron Vincent L. , Allegretto Michael , Seemann Robert , Harris Jeffrey R. , Seikaly Hadi , Côté David W. J.
Published: November 2021

Background

Fine needle aspiration (FNA) is a common diagnostic tool used in the initial evaluation of parotid masses. In the literature, variable diagnostic accuracy of FNA is reported. Therefore, when considering clinical management of these patients, the utility of FNA is unclear. The aim of this study was to determine the capability of ultrasound-guided FNA to differentiate between benign and malignant neoplasms. Further, the way in which FNA results affect clinical decision-making was assessed.

Methods

Retrospective data were collected for all patients who underwent parotidectomy at a large Canadian tertiary care center between 2011 and 2016. Patient demographics, preoperative imaging reports, preoperative FNA results, and final pathological diagnosis were analyzed.

Results

Of the 199 patients who underwent parotidectomy, 184 had preoperative ultrasound-guided FNA. There were a total of 13 non-diagnostic FNAs. In diagnosing malignancy, FNA had a sensitivity and specificity of 71.4% and 98.7%, respectively. The positive predictive value (PPV) was 83.3%. The negative predictive value was 97.5%. Of the non-diagnostic FNAs, 2 out of 13 (15.4%) were deemed malignant neoplasms on final pathology.

Conclusion

FNA is a useful adjunct in the work-up of parotid masses, but it should be used with caution. Due to limited sensitivity, it should not be relied upon as the sole determinant of a surgeon’s management plan.
Rethinking journalism standards in the era of post-truth politics: from truth keepers to truth mediators
Authors: Michailidou Asimina , Trenz Hans-Jörg
Published: November 2021

In this article, we argue for a pragmatic understanding of the role of news media and journalism not as truth keepers but as truth mediators in the public sphere. In the current debate on ‘post-truth politics’ the emphasis is often put on the formulation of ethical guidelines and legal solutions to regain control over ‘unbound journalism’ or to re-establish truth in the news media. Instead of holding journalists individually accountable for the spread of fake news, we consider truth as an unstable outcome of fact-finding, information-seeking and contestation, where journalists act as professional brokers. Journalists are not individuals that are closer to facts or more devoted to truth than others. They are rather embedded in a professional field of journalism practices that help to establish the value of information in a trusted way that becomes acceptable and convincing for the majority. Standards and procedures of journalism can therefore not be applied in a way to detect truth in an absolute way and defend it against falsehood, but to approach truth in the most reliable and acceptable way. The truth value of information then becomes the (unstable) outcome of a democratically necessary procedure of critical debate facilitated by journalists.
Grandchild Caring and Late-Life Depression: A Comparative Longitudinal Study in China and Europe
Authors: Yang Yazhen
Published: November 2021

The impact of grandparenting on the grandparents’ health has been relatively under-studied. This study examined country differences in the effects of grandchild care provision on the grandparents’ depression in Italy, Spain, China, Denmark and Sweden using the longitudinal Harmonised CHARLS and SHARE data collected between 2010–2015. Controlling for the grandparents’ depression in 2011, grandmothers providing non-intensive grandparental care in Sweden in 2013 reported lower depression score in 2015 compared to those who did not provide any care in 2013. Chinese grandfathers, Italian and Swedish grandmothers who provided intensive grandchild care reported lower depression score compared to their counterparts who did not provide any grandchild care. This study indicates that the Structural Ambivalence Theory can only partially explain the findings, suggesting further theoretical development in this area. Future research can focus on identifying the causal pathways between grandparenting and wellbeing, and the implications of such pathways for older persons’ wellbeing worldwide.
Children First? Intra-Household Inequality in Reconstituted Couple Households
Authors: Lanau Alba
Published: November 2021

An increasing number of children are growing up in reconstituted households, formed by a couple and a non-common child. Reconstituted households tend to be poorer, which is associated with worse behavioural and developmental outcomes. Additionally, there is evidence that non-common children receive less economic support from their parents upon leaving the parental home. Using age-specific deprivation data collected in the 2014 European Survey on Income and Living Conditions this article compares the allocation of resources in reconstituted and intact couple households. It shows that indeed, children in reconstituted households are more likely to be deprived compared to those in intact households. However, it finds no evidence that reconstituted households are less likely to prioritise children. The findings hold across welfare regimes. Women are more likely to go without compared with men, although differences are small.
Men in Mixed-Orientation Marriages in Contemporary China: Unpacking the Role of Heteronormativity and Patriarchy
Authors: Song Changhui , Chatterjee Joyee Shairee , Doane Donna L. , Doneys Philippe
Published: November 2021

This qualitative study based on 34 in-depth interviews (IDIs) with cis-gendered tongzhi (men who are attracted to men) critically explores the factors influencing their decisions to enter mixed-orientation marriages (MOMs) in China. Theoretically, the study weaves together insights from queer and feminist theorizing and analyzes the role of heteronormativity and patriarchy, especially in relation to hegemonic masculine ideals, in the context of marriage norms in contemporary China. Our examination showcases the contradictory role heteronormativity and patriarchy play in simultaneously marginalizing and privileging these groups of men along the axes of sexual, gender, and lineage (inter-generational) hierarchies. It also underscores the continued role of filial piety norms. Overall, the study contributes to deepening our understanding of the complex nature of MOMs and discussions of MOMs as marriage fraud. We argue that examining these non-normative marriages furthers explication of the social structures underpinning gender and sexuality in a context of patriarchal marriage-normative societies.
Zebrafish Beyond the Bench: The ‘Plataforma Zebrafish Open Doors’ Programme
Authors: Disner Geonildo Rodrigo , Pimentel Falcão Maria Alice , Lima Carla , Lopes-Ferreira Monica
Published: November 2021

The Butantan Institute is a pioneering Brazilian health sciences institution, which also houses a large science park with museums that contribute to ongoing science education for schools and the wider community. In recent years, as part of Butantan Institute’s Plataforma Zebrafish™, zebrafish embryos have been used for the dissemination of scientific knowledge during on-site events and as part of outreach campaigns to non-scientific audiences, mostly children. The aim of this work is mainly to demystify the activities of the scientific researcher, highlight the role of science in the furthering of knowledge, and increase public interest and confidence in science. In this article, the Institute’s ‘Plataforma Zebrafish Open Doors’ programme is described, which offered guided tours of the laboratory facilities. The tours gave visitors the opportunity to observe zebrafish research and embryo development, and to use the knowledge gained from this experience as a framework for understanding fundamental ethical issues. During the 2-day event, around 800 visitors (most of them school-age children) attended. Together with the guided tours, our experience of outreach offered meaningful opportunities to bring children and members of the public closer to science and ‘real-life’ scientists, hopefully inspiring and encouraging the next generation of scientists. It also gave the scientists an opportunity to engage more closely with wider society. We believe that these activities also substantially contribute to the wider dissemination of relevant experimental results that have been obtained with public funding and that impact society in general.
Linking SME international marketing agility to new technology adoption
Authors: Thoumrungroje Amonrat , Racela Olimpia C
Published: November 2021

This article proposes an alternative conceptualisation and operationalisation of international marketing agility as a higher-order dynamic capability constituting overseas market-sensing decision-making flexibility and international marketing adaptability. The international marketing agility – new technology adoption relationship was examined under the moderating effects of new technology relative advantage and complexity among a sample of 162 small and medium sized enterprises (SME) exporters in Thailand, where new internet-enabled inventory management systems were being promoted. The self-administered survey data were analysed using multiple-group structural equation modelling. Results reveal that new technology adoption is driven by higher-level competencies such as international marketing agility, which develops, integrates and reconfigures resources through the three first-order capabilities to enable SME exporters to cope with volatile environments. Such adoption is enhanced by SME exporter perceptions of internet-enabled inventory management system’s relative advantage, but is otherwise diminished by perceptions of its complexity. These findings provide important implications for policymakers and technology vendors responsible for securing adoption by SMEs in emerging markets.
Comparing Rates of Sexual Assault Between Panel Quota and Social Media Samples: Findings Across Sexual Orientation Categories
Authors: Canan Sasha N. , Kaplan Alejandra M. , Jozkowski Kristen N.
Published: November 2021

Sexual assault is prevalent and may be even more prevalent among sexual minorities. However, prevalence rates vary, in part, due to discrepancies in sampling methods. Given this, we assessed whether two popular non-probability sampling types (panel quota vs. social media recruitment) produced different sexual assault prevalence rates when holding all other methodological choices (definitions, measures, scoring) constant in a sample of lesbian, bisexual, queer, and heterosexual adults, excluding cisgender men. Two phases of data collection occurred—a panel quota sample ( n = 1366), recruited from an online sample aggregator, and social media sample ( n = 1102), recruited through lesbian, gay, bisexual, transgender, and queer (LGBTQ) social media sites. Participants were asked about sexual assault and rape experiences in both childhood and adulthood using a modified form of the Sexual Experiences Scale-Short Form Victimization. Both phases used the same definitions of sexual assault, prevalence measures, and prevalence scoring. Overall, the sample recruited via LGBTQ social media yielded statistically higher sexual assault prevalence rates for all four types of victimization experiences measured: lifetime sexual assault (LSA), rape-specific LSA, childhood sexual assault (CSA), and adulthood sexual assault. However, when parsing out subgroups, this finding only held for heterosexual participants who had rates > 30% higher in the social media sample compared with the panel quota sample. These findings suggest that researchers studying sexual assault in lesbian, bisexual, or queer adults may be able to use social media sampling techniques, which require less resources, without concern that the sampling technique is inflating prevalence when compared to panels.
For the Life of the World? And of the Church too! Quality of Ethics as a Diagnostic Key for the Orthodox Church
Authors: Thermos Vasileios
Published: November 2021

This article attempts an overall assessment of the Ecumenical Patriarchate document on Orthodox social ethics, For the Life of the World, articulated along three dimensions: a) Radicalism, in terms of the radical reminders on Orthodox morality that the document succeeds in highlighting, b) Pervasiveness, with regard to the question on how the principles exposed in the document are (or should be) valid across all local Orthodox Churches, and c) Consistency, as the inner harmony between these principles and other aspects of Orthodox ecclesiastical life. It is opined that this document is of historical significance and that it can be of great benefit for the entire Church, if applied. Amidst an advanced modernity and on a critical crossroad with post-modernity, a renewal of Orthodox social ethics that both takes under consideration scientific findings and speaks a contemporary ‘language’ that faces subjectivity seriously, was especially necessary. Hereafter, what is at stake is the degree this document will be disseminated, accepted and influential.
Closeness to singularity based on kinematics and dynamics and singularity avoidance of a planar parallel robot with kinematic redundancy
Authors: Hu Lanqing , Gao Haibo , Qu Haibo , Liu Zhen
Published: November 2021

Planar parallel robots are appealing due to their structural simplicity, high stiffness, and large payload capacity. One major problem is that workspace and singularity of non-redundant parallel robots are unchangeable. Hence, when the desired path crossed with singularity or exceeded the workspace’s boundary, the robot is incapable of finishing the task. Another one is closeness to singularity. If one can know the distance between the end manipulator and singularity or workspace’s boundary, the robot will avoid lose control or breakdown. Compared with the traditional planar parallel robot, the planar parallel robot with kinematic redundancy possesses the advantages of avoiding singularity, expanding workspace by adjusting kinematic redundancy parameter. Therefore, the objective of this article is to present an offline action-strategy of a planar robot with kinematic redundancy to measure the closeness to singularity and avoid singularity. It includes two main parts: First, before the robot moves along the desired paths, the closeness to singularity was measured based on the performance of the kinematics and dynamics so that one can know where to pause the robot. Second, an algorithm is designed to previously find the proper kinematic redundancy parameters for changing singularity and workspace. Hence, the robot can smoothly move far from the singularity to finish all paths. The results indicate that the robot can adjust its configuration to well realize the goal by the offline action-strategy.
Neural Representations of the Committed Romantic Partner in the Nucleus Accumbens
Authors: Ueda Ryuhei , Abe Nobuhito
Published: November 2021

Having an intimate romantic relationship is an important aspect of life. Dopamine-rich reward regions, including the nucleus accumbens (NAcc), have been identified as neural correlates for both emotional bonding with the partner and interest in unfamiliar attractive nonpartners. Here, we aimed to disentangle the overlapping functions of the NAcc using multivoxel pattern analysis, which can decode the cognitive processes encoded in particular neural activity. During functional MRI scanning, 46 romantically involved men performed the social-incentive-delay task, in which a successful response resulted in the presentation of a dynamic and positive facial expression from their partner and unfamiliar women. Multivoxel pattern analysis revealed that the spatial patterns of NAcc activity could successfully discriminate between romantic partners and unfamiliar women during the period in which participants anticipated the target presentation. We speculate that neural activity patterns within the NAcc represent the relationship partner, which might be a key neural mechanism for committed romantic relationships.
Homeward bound: mapping Clandestine transportation into France during the Second World War
Authors: Foulk David Arthur
Published: November 2021

From 1940 to 1944, a clandestine war raged in France, with agents and resistance networks being supplied by the Allies. This work brings together digital humanities methodologies, oral history, new archival sources and historiographical analysis to uncover the dangerous nature of wartime logistics and transportation that helped to liberate France. From the Section 61 packing units to N°. 161 (Special Duties) Squadron's Lysander and Hudson pilots, the existing scholarship is clarified and expanded. Moreover, this article cartographically plots French resistance transport operations, underlining the importance of Allied cooperation towards France's freedom from occupation.
Contesting Agricultural Markets in South Asia: Farmer Movements, Co-operatives and Alternative Visions
Authors: Kadirgamar Ahilan , Rashid Hashim Bin , Shah Amod
Published: November 2021

Recent laws for privatizing agricultural produce markets in India are just one prominent example of long-running efforts to liberalize agriculture across South Asia. These legacies of state withdrawal from agriculture and the growing role of private intermediaries in both input and output markets have precipitated simultaneous crises of reproduction and accumulation in the countryside. However, such trajectories of liberalization are both context-specific and politically contested. Drawing from two cases—the Pakistan Kissan Ittehad’s efforts to build a broad political coalition among differentiated agrarian producers to contest the place of farmers in agricultural markets and the Northern Sri Lanka co-operative movement’s autonomous initiatives for post-war rural reconstruction—this article argues that rural movements are providing new and alternative visions for how farmers can engage with liberalizing agricultural markets on more equitable terms.
The Entrepreneurial Story and its Implications for Research
Authors: Brattström Anna , Wennberg Karl
Published: November 2021

Research is not merely report-writing; it also involves elements of storytelling. In this essay, we reflect on two narrative archetypes in entrepreneurship research: the stories of entrepreneurship as a road to salvation and means to emancipation. We outline a framework to analyze research from a storytelling perspective, apply this framework to identify implicit assumptions and methodological biases in mainstream research, and discuss how a storytelling framework can be used to generate alternative stories. We argue for a more empirically grounded research agenda that continues the development of entrepreneurship research into a rich and diverse field.
Periductal Stromal Tumor of the Breast: One Institution's Review of 6 Tumors Over a 22 Year Period With Immunohistochemical Analysis
Authors: Zhao Longmei , Komforti Miglena K. , Dawson Andrea , Rowe J. Jordi
Published: November 2021

Introduction. Periductal stromal tumor (PST) of the breast is a rare fibroepithelial neoplasm with controversial pathogenesis. Methods. A retrospective search of our Pathology database from 2000 to 2021 identified 6 PST, all evaluated according to the Armed Forces Institute of Pathology (AFIP) criteria. Immunohistochemistry for CD10, CD34, KIT, GATA3, p63, SOX10, ER, PR, HER2, smooth muscle actin (SMA), beta-catenin, and myogenin was performed as well. Results. All 6 patients were female and age ranged from 29 to 55 years (mean 40 years). Tumor size ranged from 2.9 to 5.9 cm (mean 3.0 cm). Data showed absence of leaf-like architecture (0/6), at least moderate hypercellularity (6/6), lack of a circumscribed border (5/6), coalescing nodules with intermixed adipose tissue (4/6), at least moderate stromal atypia (4/6), and an elevated mitotic activity ≥3mitotic figures/10 HPF (6/6). The stromal cells were positive for CD10 (4/4), CD34 (4/4), KIT (3/4), and SMA (3/4), and negative for GATA3 (0/6), p63 (0/6), SOX10 (0/6), ER (0/4), PR (0/4), HER2 (0/4), nuclear beta-catenin (0/5), and myogenin (0/4). No patient had a PST recurrence or metastasis (average follow-up of 91 months). Conclusion. We confirm that PST shares morphologic and immunophenotypic similarities with phyllodes tumor (PT). However, PST can be reliably differentiated from PT using the AFIP criteria. Additionally, PST's immunoprofile of positive KIT and CD34 stromal expression alongside the negative GATA3, p63, and SOX10 reactivity can aid the pathologist in excluding metaplastic carcinoma. All 6 of our PST behaved as benign neoplasms akin to benign PT.
Gender Differences in Law Enforcement Officer Stress and Coping Strategies
Authors: Bonner Heidi S. , Brimhall Andy
Published: November 2021

Law enforcement officers, like many professionals, are not immune to the effect of stress on their overall health. In fact, law enforcement officers may be particularly vulnerable to these effects due to unique and sometimes traumatic stressors inherent in their work. Further, male and female officers may experience the stressors of the law enforcement profession, and the coping strategies used in response to stress, differently. Using survey data collected from a sample of law enforcement officers in a large urban police agency in the southeastern United States, this research examines the differences between male and female officers in terms of perception of stressors in policing and coping strategies used in response to stress. The findings indicate that female officers have significantly higher mean stress scores on several items (particularly those regarding safety factors) and are significantly more likely to use positive coping strategies compared to male officers.
AURKB as a Promising Prognostic Biomarker in Hepatocellular Carcinoma
Authors: Xiao Jingchuan , Zhang Yingai
Published: November 2021

The Aurora kinases form a family of 3 genes encoding serine/threonine kinases and are involved in the regulation of cell division during the mitosis. This study was designed to investigate the prognostic role of Aurora kinases in hepatocellular carcinoma (HCC). In this study, we analyzed the expression, overall survival (OS) data, promoter methylation level, and relationship with immunoinhibitors of Aurora kinases in patients with HCC from GEPIA2, UALCAN, OncoLnc, and TISIDB databases. Protein-protein interaction (PPI) network, gene ontology, Kyoto Encyclopedia of Genes and Genomes (KEGG), and Reactome pathway analysis were performed using the STRING database and Cytoscape software. We found that the mRNA expression, stages of HCC, and OS of AURKA and AURKB in HCC tissues were significantly different from control tissues, but there were significant inconsistencies in promoter methylation level and relationship with immunoinhibitors for AURKA and AURKB. None of the above items were significantly different for AURKC. Furthermore, a hub module including AURKA, AURKB, and AURKC was identified within the PPI network constructed with the Molecular Complex Detection (MCODE) plug-in in Cytoscape software. Our results show that AURKB could be a potential biomarker for HCC prognosis.
Normal Island: COVID-19, Border Control, and Viral Nationalism in UK Public Health Discourse
Authors: Fitzgerald Des
Published: November 2021

In this contribution, I present emergent analysis of a preoccupation with managing COVID-19 through border control, among non-Governmental public health actors and commentators. Through a reading of statements, tweets, and interviews from the ‘Independent Sage’ group – individually and collectively – I show how the language of border control, and of maintaining immunity within the national boundaries of the UK, has been a notable theme in the group’s analysis. To theorize this emphasis, I draw comparison with the phenomenon of ‘green nationalism’, in which the urgency of climate action has been turned to overtly nationalistic ends; I sketch the outlines of what I call ‘viral nationalism,’ a political ecology that understands the pandemic as an event occurring differentially between nation states, and thus sees pandemic management as, inter alia, a work of involuntary detention at securitized borders. I conclude with some general remarks on the relationship between public health, immunity, and national feeling in the UK.
‘How Goopy are you?’ Women, Goop and cosmic wellness
Authors: Conor Bridget
Published: November 2021

In this article, I’ll outline the phenomenon of ‘cosmic wellness’ which is now visible across on- and offline spaces that promote health and well-being products and practices to women. Cosmic wellness is a broad constellation of media, discourse, imagery, materials and foods (including crystals, dust and herbs) produced primarily by white, wealthy women. On the one hand, cosmic wellness can be read as a digital food culture that offers healthy and potentially necessary responses to fiercely neoliberal modes of working and living. But conversely, it is framed as the newest example of narcissistic self-absorption and, more seriously, as unhealthy and dangerous. Cosmic wellness is founded on various beliefs, including the moral necessity of pursuing the optimisation of self and the power of markets to provide the ingredients, tools and practices to achieve it. It is connected to histories that chart the incorporation of New Age health and well-being practices into ‘mainstream’ forms of lifestyle production and consumption and the simultaneous derision of these practices, especially when used and promoted by women. But there is also something new about cosmic wellness, especially as it is visible online on platforms such as Instagram. In the article, I outline the key features of cosmic wellness and analyse its contemporary cultural purchase, using theories of digital food cultures, spiritual production and consumption, postfeminism and critical whiteness studies. The article then conducts empirical analysis of a series of Instagram posts from one prominent space in which cosmic wellness currently circulates: Gwyneth Paltrow’s lifestyle and wellness business Goop.