bluuebunny/crossref_metadata_2025 huggingface dataset:
Erken Bir Veda: Meltem Nass Duce Anısına
Authors: APAYDIN F. Demir
Published: May 2023

Prof. Dr. Meltem Nass Duce, 27 Mayıs 1968’de Malatya’da doğdu. TED Zonguldak Koleji’nden 1986’da, Marmara Üniversitesi Tıp Fakültesi’nden 1992’de dönem üçüncüsü olarak mezun oldu. Radyoloji uzmanlık eğitimini Çukurova Üniversitesi Tıp Fakültesi Radyoloji Anabilim Dalı’nda 1993-1998 yılları arasında tamamladı. 1998’de Mersin Üniversitesi Tıp Fakültesi’ne öğretim üyesi ve Radyoloji Anabilim Dalı kurucu başkanı olarak atandı. Mersin Üniversitesi’ndeki çalışma hayatı boyunca Radyoloji Anabilim Dalı başkanlığını yürüttü. Ağırlıklı olarak, Meme Radyolojisi, Kas-İskelet Sistemi Radyolojisi, Baş-Boyun Radyolojisi ile ilgilendi; çok sayıda bilimsel çalışmaya imza attı, çok sayıda ders verdi. Akademik çalışmalarının yanı sıra, idari görevlerde de bulundu: 1999-2002 yılları arasında başhekim yardımcısı, 2014-2023 yılları arasında başhekim olarak calıştı. 25 Mart 2023’de erken bir vedayla aramızdan ayrıldı. Biz; çalışkan, görev bilinci yüksek, bilgili ve becerili, mücadeleci, azimli, özverili, adil, vicdanlı, üst düzey eğitim becerilerine sahip, başarılı bir hekimi, bir akademisyeni, bir eğitmeni, ülkesini çok seven çağdaş bir cumhuriyet kadınını çok erken kaybettik. Saygıyla, sevgiyle, özlemle anıyoruz.
Arts and Culture Education in Bali Urban Sketchers Community Activities: A Netnographic Study Perspective
Authors: Adipurwa Anak Agung Trisna Ardanari , Udiyana Wasista I Putu , Resi Kerdiati Ni Luh Kadek , Ari Darmastuti Putu , Penerbitan Pusat
Published: May 2023

Urban Sketchers Bali (USK Bali) is a community engaged in capturing life's moments in the surrounding environment through sketches. Cultural moments become objects most often used as sketches. In the process, USK Bali members come from various professional backgrounds, from artists to those without an artistic background. Then there is an interesting phenomenon in transferring knowledge about art and culture. USK Bali members do not have a professional educator background, but the learning process and learning climate are conducive and enjoyable. The purpose of this study is to see the educational process that occurs both in its interactions and strategies. This research is qualitative with a netnographic approach, which summarizes and analyzes a sample of interactions on social media. The result is that naturally and instinctively, the educational process that is formed already uses four approaches in education: behavioristic, cognitivist, constructivist, and humanist. This process shows that in the spontaneous transfer of knowledge, someone already has all of these approaches even though they do not have a professional educator background.
The Concept of Tri Hita Karana in Kakawin Siwaratrikalpa as a Means to Interpret Life
Authors: Suminto Suminto , Kustiyanti Dyah
Published: May 2023

Old Javanese literature, especially Kakawin Siwaratrikalpa, has an essential role among the Hindu community in Bali, not only because of its captivating story elements but also because it is essential for human life as it contains artistic values, religious values, moral teachings (ethics), manners, character education, philosophy, law, and morals. Tri Hita Karana is a concept of balancing the relationship between humans and God, humans and others, and humans and their natural environment to achieve prosperity and harmony in life in the world. Human life has undergone significant changes due to the changing times. The demands of modern life have brought human behavior to problems that need attention. The advancement of science and technology has caused a shift in social values, which has led humans to promiscuity, moral decline, the conflict between religious communities, lifestyle changes, environmental degradation, exploitation of natural resources, and even environmental destruction. This research is qualitative descriptive research by applying the concept of Tri Hita Karana. The source of the data is scientific, meaning that apart from observing texts, researchers are trying to observe and understand empirical phenomena directly in people's lives. The theory used is the theory of Human Relations. The results of the discussion prove that the three parts of the Tri Hita Karana concept are always related and cannot be separated. Humans, as the main actors in life, must continue to seek and strive for a safe, peaceful, and happy life.
Authenticity and Commodification of Creative Industry Products in The Tourism Sector, Bali
Authors: Prasiasa Dewa Putu Oka , Widari Dewa Ayu Diyah Sri , Susanti Putu Herny
Published: May 2023

The creative industry places an emphasis on the creativity of a product, the understanding that the creator is known and has a copyright. In addition, the creative industry has links with the cultural industry, because its products are components of culture. When market tastes lead to post-industry, it is found that creative industry products consumed by tourism experience a change from homogeneous to heterogeneous with mass production. Changes in market tastes encourage the emergence of highly varied creative art products, as a result of the creative economy industry. The entry of the creative economy industry into the realm of culture, which then develops into the cultural industry, apart from growing the local and national economy, also has an impact on cultural components, especially from the aspects of authenticity and commodification. The areas affected include performing arts, tourism, entertainment, fashion, craft products, and culinary. In order to increase the competitiveness of Indonesian tourism, especially from the cultural pillar, the aspects of authenticity and commodification can increase its contribution to the local and national economy through the implementation of internationalization, traditionalization, and sacred versus profane.
Revised European Association for Palliative Care (EAPC) recommended framework on palliative sedation: An international Delphi study
Authors: Surges Severine Marie , Brunsch Holger , Jaspers Birgit , Apostolidis Kathi , Cardone Antonella , Centeno Carlos , Cherny Nathan , Csikos Agnes , Fainsinger Robin , Garralda Eduardo , Ling Julie , Menten Johan , Mercadante Sebastiano , Mosoiu Daniela , Payne Sheila , Preston Nancy , Van den Block Lieve , Hasselaar Jeroen , Radbruch Lukas
Published: May 2023

  

As part of the Palliative Sedation project funded by the European Union’s Horizon 2020 programme (grant no. 825700) entitled Palliative Sedation (SC1-BHC-23-2018 A) (https://palliativesedation.eu), the aim of our study was to revise and update the 2009 European Association for Palliative Care (EAPC) framework on palliative sedation. For this framework as for other guidelines on palliative sedation the general weakness of its methodological development and the lack of consensus on terminology and concepts has been criticized, and issues such as the complexity of assessing refractory symptoms or the differentiation between somatic, psychological and existential suffering have remained under controversial debate. 

For the new framework a rigid consensus methodology with a four-step Delphi procedure involving international experts and a European cancer patient organisation has been used. The development of the recommendations addressed all relevant methodological and content aspects of the Appraisal Guideline Research and Evaluation II (AGREE II), and the reporting was based on the standards for Conducting and Reporting Delphi Studies (CREDES).

To our knowledge, this is the first evidence- and consensus-based guidance on palliative sedation for healthcare professionals involved in the care of adult patients with life-limiting disease in all settings. It is structured into 42 statements and explanatory texts, for which a high or very high level of consensus has been reached among experts from 28 different countries with a broad range of professions, and a European patient organisation. It has been endorsed in January 2023 by the EAPC board of directors. The importance of patient autonomy is emphasised in all phases of the process. It provides guidance on the decision-making process and on the way palliative sedation should be administered, monitoring tools as well as a step-by-step pharmacological approach with a detailed description of recommended medications and a more detailed guide to hydration decision-making based on the recent literature.
A concepts and techniques related to the DC motor speed control system design: Systematic Review
Authors: Muhammad Hilal Mthboob  , ALRikabi Haider , A. Aljazaery Ibtisam
Published: May 2023

The first sources of direct current (DC) were invented, DC machines were one of the first types of electro-mechanical machines used. DC machines are more advantageous over AC machines as regards to Speed regulation and versatility. A DC motor is an electrical actuator with a lot of control that is used in a lot of applications, like robotic manipulators, guided vehicles, steel rolling mills, cutting tools, overhead cranes, electrical traction, and other applications. Due to their speed-torque characteristics and ease of control, DC motors are utilized extensively in industries for demanding variable speed applications. In terms of controller design and implementation, the process control industry has seen numerous advancements over the past two decades. In the industry, there is a great demand for automatic controllers that can respond quickly and accurately to perform precise tasks. The feedback loop is an essential component of system control that must be utilized in order to achieve the desired performance in the majority of systems. Numerous control strategies have been developed for various feedback control systems in order to achieve rapid system dynamic response. Controls in a drive system are crucial if the reference speed is to be accurately and quickly tracked, with little or no steady-state error and as little overshoot as possible. This paper presents the Systematic literature review that was conducted as covers pertinent established concepts and techniques related to the DC motor speed control system design, for applications that require actuators with accurate speed characteristics. Simulation and real time implementation results employed for DC motor speed control systems in various literature are analysed and discussed.
Credit Card Fraud Detection Using LSTM Algorithm
Authors: Mohmad Yanash Azwin
Published: May 2023

With the rapid growth of consumer credit and the huge amount of financial data developing effective credit scoring models is very crucial. Researchers have developed complex credit scoring models using statistical and artificial intelligence (AI) techniques to help banks and financial institutions to support their financial decisions. Neural networks are considered as a mostly wide used technique in finance and business applications. Thus, the main aim of this search is to help bank management in scoring credit card clients using machine learning by modelling and predicting the consumer behavior with respect to two aspects: the probability of single and consecutive missed payments for credit card customers. The proposed model is based on the bidirectional Long-Short Term Memory (LSTM) model to give the probability of a missed payment during the next month for each customer. The model was trained on a real credit card dataset and the customer behavioral scores are analyzed using classical measures such as accuracy, Area Under the Curve, Brier score, Kolmogorov–Smirnov test, and H-measure. Calibration analysis of the LSTM model scores showed that they can be considered as probabilities of missed payments. The LSTM model was compared to four traditional machine learning algorithms: support vector machine, random forest, multi-layer perceptron neural network, and logistic regression. Experimental results show that, compared with traditional methods, the consumer credit scoring method based on the LSTM neural network has significantly improved consumer credit scoring.
Assorted Aspects and Implementation Patterns of Artificial Intelligence to Reduce Cyber Crimes
Authors: Prof. Dr. M . Randles
Published: May 2023

Cyber crime was a major problem even before the epidemic, and it skyrocketed as the globe became increasingly digital after the pandemic began. It is crucial to think about how to make the web safer in the post-pandemic period, since the number of cyber scams is rising rapidly. With more people doing remote work and more people quickly embracing new technology, as well as with decreased monitoring and controls, hackers have more opportunities to attack weaknesses in the system. Individuals and businesses were rendered more vulnerable to cyber fraud as a result of each of these developments brought on by the epidemic. Since cybercriminals are just as technically savvy as their cyber security counterparts, a lot of effort and money must be spent on prevention. Professionals in the field of cyber security and cybercriminals nowadays share many of the same skills and use many of the same tools. Both cyber security experts and cybercriminals rely on them, but the former to protect their systems from the latter.
An Automation system over Cloud by Using Internet of Things Applications
Authors: Butler Kevin
Published: May 2023

By the virtue of blooming automation industry and wireless connectivity, all the devices within the home can be connected. Today's World is moving to digitalization where everything is made easy and comfortable for people i.e., young youth as well as senior citizen. Smart Automated House Application using IOT (Internet of Thing) is a system where basic house facility can be handled by device from any place such as ON and Off of Light, Fan, AC, Water pump, Gardening of Water. One can handle all these things with help of device NodeMCU ESP8266, Android Application, Internet Connection. This paper include functionality of node esp8266 are connected with either of above given house application like fan, light, water pump, gardening with help of coding and hosting online with web server. All the functionality is handled by Mobile App created in android application, from which house application are controlled with help of internet. This paper is clarifying that monitoring of circuit devices through wireless using Node MCU and controlling using App Blynk. According to requirement of need one can connect multiple device like sensors, appliance and many more till 8.
A critical review of Optimization MANET routing protocols
Authors: Al Ogaili Riyadh , Hakem Alsaeedi Ali , Saad Alkafagi Salam , Saeed D. Alfoudi Ali
Published: May 2023

The main challenges in routing protocols are node mobility, resource constraints, error-prone channel states, and problems with hidden and unprotected terminals. This article provides an overview of the main protocols, their problems, and ways to improve them. The cell phone allows communication between two moving units via mobile stations (MS), mobile units, and landing units. The term "mobile ad hoc network" (MANET) refers to a group of devices connecting and communicating. The military, law enforcement, and emergency services have quickly become interested in MANETS because they provide a high quality of service. Path loss (PL), one of the biggest problems in wireless communications, can be caused by multiple reflections from an obstacle or by the source of the signal being far from the destination on the network. Multipath propagation, path loss, and interference reduce the network's quality of service (QoS). The best route is added to a router's routing table using a dynamic routing protocol, and an alternate path is chosen when the primary route is unavailable.
On Soft Pre-Compact Maps
Authors: Mustafa Shamkhi Eiber  , Hassan Kadhem Hiyam
Published: May 2023

This paper holds to establish a soft pre-compact map and to investigate its associations with soft pre-compact maps, almost soft pre-compact maps, A-almost soft compact maps, A*-almost soft compact maps, mildly soft semi-compact maps, M-mildly soft compact maps besides M*-mildly soft compact maps which are utilized from the relations between their spaces under some conditions or without conditions. Consequently, the composition factors of soft pre-compact maps with soft pre-compact maps, almost soft pre-compact maps, and mildly soft pre-compact maps, A-almost soft compact maps, M-mildly soft compact maps are studied based on the previous association between them. Many examples are given to explain the relationships between the topologies and relations of the soft set.
New Types of Continuous Function and Open Function
Authors: Ali Zubain Nassir , Khalif Hussain Ali
Published: May 2023

In this paper, we continue to study the properties of the relation with some type of open sets, and we introduce  -continuous function, semi-continuous function, -continuous function, and  -continuous function are studied and some of their characteristics are discussed. In this work, we need to introduce the concepts of function, especially the inverse function to find all continuous function, so we want to prove some examples, theorems, and observations of our subject with the help of new concepts for the alpha-open sets of sums to make it easier for us to find a relationship between these formulas as well as the converse relationship has been studied and explained with illustration many examples. Hence, reaching to get a relationship (continuous, -continuous, semi -continuous) function at new condition.
A Novel Arabic Words Recognition System Using Hyperplane Classifier
Authors: Abdegadir Khalifa Mahmoud , Mohammed Ali Ammar , Dr.Saif Ali Abd Alradha Alsaidi  , Zheng Liying , Fadel Alwan Nahla , Saeed Mahdi Gadiaa
Published: May 2023

Topic of exhaustive study for about past decades has been carried out in machine imitation of human reading. a small number of investigates have been accepted on the detection of cursive font writing like Arabic texts for its individual challenge and difficulty .In this work, a novel technique for automatic Arabic font recognition is proposed to demonstrate an suitable recognition rate for multi fonts styles and multi sizes of Arabic word images.

The scheme can be classified into a number of steps. First, segmenting Arabic line into words depending on the vertical projection and dynamic threshold then we implicated  each  Arabic word as a class by ignoring segmenting the word into characters .Second ,normalizing step, the size of Arabic word images varies from each other .The system converts  the images that contribution into a new size that  is divisible by "N" without remainder, to decrease the difficulty of feature extraction and recognition of  the system that may allow images from different resources, Third,  feature extraction step which is based on apply the ratio of vertical sliding strips as a features. Finally, multi class support vector machine (one versus one technique)is used as a classifier .This method was estimated on off line printed fonts, five Arabic fonts, (Andalus, Arial, Simplified Arabic, Tahoma and Traditional Arabic) were used and the average  recognition rate of all fonts was 95.744%.
Kınalı Keklik (Alectoris chukar) Sirinks’inde Desmin, Vimentin ve Laminin Lokalizasyonu
Authors: Bayram Bayram , Topaloğlu Uğur , Aydın Nurşin , Çelenk Fatma
Published: May 2023

Kuşlarda sesin yaşamlarındaki önemi günümüze kadar birçok araştırmacının ilgisini çekmiştir. Bununla ilgili yapılan geniş çaplı çalışmalar erkeğin ötüşünün dişinin karar kılmasında önemli etkileri olduğunu, erkeğin muhtemel hormonal durumu ve fiziksel gücü hakkında bilgi veriyor olabileceğini, bu durumun dişinin eş seçiminde karar kılmada etkili olabileceğini düşündürmektedir. Memelilerdeki gibi larinks bulunmasına karşın kuşlar şarkılarını söylemek için göğüslerinin derinliklerine yerleşmiş trakea ve akciğerler arasında lokalize olan sirinksi kullanmaktadırlar. Çalışmamızın amacı, desmin, vimentin ve laminin’in sirinks üzerine olası etkilerini araştırmaktır. Bu kapsamda sirinks’in epitel dokusu, kas dokusu, kıkırdak dokusu ve bezleri incelenmiş ve bu filamanların varlıkları histolojik olarak immünohistokimyasal yöntemler kullanılarak araştırılmıştır. Yapılan incelemeler sonucu desmin, vimentin ve laminin’in erkek ve dişi kınalı keklikler arasında değişkenlik göstermediği tespit edildi. Desmin ve vimentin’in düz kas hücrelerinde orta yoğunluklu bir reaksiyon gösterdiği görüldü. Laminin’in kaslarda güçlü reaksiyonlar gösterdiği; bezlerde, epitelyum hücrelerinde ve damar duvarlarında da güçlü reaksiyonlar gösterdiği görüldü. Elde edilen bu verilerden yola çıkarak bu intermediyer filamanların, keklik sirinksindeki hücre gruplarının iskelet yapısına katılarak hücrelerdeki homeostazının sağlanmasında ve organın fonksiyon gördüğü fizyolojik süreçlerin devamlılığında etkileri olduğunu söyleyebiliriz.
MAKALAH MEMBERDAYAKAN MARGINALISASI TERHADAP PEDAGANG KAKI LIMA UNTUK MENINGKATKAN PENDAPATANNYA
Authors: Memei
Published: May 2023

LATAR BELAKANG MASALAHGolongan masyarakat marginal, pada umumnya terjebak dalam kemiskinan karena tiadanya modal dan akses-akses untuk menuju ke sumber pendanaan serta peluang usaha yang tidak memihak kepada mereka. Hasil yang diperoleh dari usaha mereka pun rata-rata minim, dimana hasil yang mereka peroleh hanya cukup untuk kehidupan mereka yang sederhana. Karena mereka masyarakat bawah tidak memiliki keterampilan, modal dan pendidikan maka banyak yang mengadu nasib menjadi pedagang kaki lima. Pedagang kaki lima adalah orang yang memiliki modal relatif rendah, berusaha dalam bidang produksi dan barang-barang untuk memenuhi kebutuhan-kebutuhan tertentu dalam masyarakat, usaha tersebut dilakukan pada tempat-tempat yang dianggap strategis dalam lingkungan. Pedagang kaki lima dan pedagang keliling berfungsi mengemban minimal tiga peran penting, yaitu sebagai penyedia kebutuhan pokok masyarakat kurang mampu dengan harga yang terjangkau, penyerap tenaga kerja dan angkatan kerja, terutama tenaga kerja yang kurang atau tidak terdidik yang selama ini menghuni kota akibat urbanisasi yang tidak terkontrol.Pedagang kaki lima tidak terlepas dari kehidupan masyarakat. Dimana pedagang kaki lima merupakan korban dari PHK dan masyarakat yang terpuruk akibat belum pulihnya kondisi perekonomian pada masyarakat.
Konsep Unnalli Melo dalam Kebudayaan Toraja dan Cerminannya dalam Tradis Ada' Tuo di Mamasa
Authors: Tangibali Dwiwanti Udeng
Published: May 2023

Unnalli Melo merupakan ideologi atau falsafah bagi masyarakat Toraja yang berarti kebajikan dengan mengutamakan perdamaian. Masyarakat Toraja menjunjung tinggi perdamaian yang rela mengorbankan segala-galanya demi sebuah keharmonisan dan kerukunan yang kemudian dalam istilah Toraja dikenal dengan Karapasan. Berdasarkan masalah yang akan diteliti oleh penulis maka penelitian ini memakai metode penelitian kualitatif dimana penulis mendapatkan data dan informasi melalui literatur terhadap Konsep Unnalli Melo tercermin dalam pelaksanaan ritual perdamaian adat di Mamasa yang didasarkan pada falsafah Ada’ Tuo. Ada’ Tuo merupakan sistem dalam masyarakat yang menjunjung tinggi pada upaya dalam menyelesaikan persoalan dengan damai. Dan merupakan dasar hidup yang menjadikan nilai-nilai kemanusiaan di atas segala-galanya yang kemudian dalam istilah Mamasa dikenal dengan somboyan Sitayuk, Sikamasei, Sirande Maya-maya, yang berarti saling menghargai dan menghormati, saling mengasihi dan saling mendukung satu dengan yang lain. Kedua falsafahini bertujuan untuk menyatukan kembali hubungan-hubungan yang terputus atau terpecahuntuk mencegah permasalahan yang lebih fatal.
PANDANGAN MASYARAKAT TORAJA TENTENG SIFAT UNNALLI MELO DALAM HUBUNGANNYA DENGAN RELASI BERAGAMA
Authors: Pagiling Rima
Published: May 2023

pluralisme dalam suatu masyarakat adalah sesuatu yang normal terjadi. Salah satunya adalah perbedaan tentang aliran kepercayaan. Konflik tentang agama sering kali ditemukan dalam berbagai realitas hidup manusia. seperti media teknologi digital dan kehidupan nyata manusia. Oleh karena itu, untuk mengembangkan penelitian tersebut penulis menggunakan metode kualitatif dengan pendekatan analisis-deskriptif dengan studi kepustakaan yang bersumber dari literatur-literatur terpercaya seperti buku, artikel dan internet yang dapat diakui kebenarannya. Tujuan dari penelitian ini adalah untuk menemukan tentang bagaimana membangun moderasi beragama yang hidup dalam keharmonisan melalui falsafah masyarakat Toraja unnalli melo (menghadirkan kebaikan) ditengah-tengah situasi yang dihadapi oleh masyarakat Indonesia. Hasil yang diharapkan dari penelitian ini adalah bahwa membangun kebaikan, kemakmuran, kesamarataan dan kepedulian dengan orang lain dapat menjadi jalan untuk membangun keharmonisan beragama dengan tujuan untuk mencapai masa depan demokrasi Indonesia yang lebih baik.
PERWUJUDAN SIMILE OLEH MERARI SIREGAR DALAM NOVEL AZAB DAN SENGSARA
Authors: Susiati Susiati
Published: May 2023

This study aims to identify the use of simile by Merari Siregar in novel’s Azab dan Sengsara. This research is a qualitative research. The data is collected using the listening method used to obtain data by listening to the use of language. The data were analyzed descriptively and The data were analyzed based on the Kridalaksana word class manifestation theory and stylistic theory by Keraf. The type of data is written data, that is simile style language in the novel’s Azab dan Sengsara by Merari Siregar.The results showed that the embodiment of simile to Merari Siregar in novel’s Azab dan Sengsara have five, namely (1) embodiment of simile in the noun class with nouns; (2) embodiment of simile in the noun class with adjectives; (3) embodiment of simile in the adjectives class with verb; (4) embodiment of simile in the verb class with verb; (5) embodiment of simile in the verb class with nouns. While, simile markers to Merari Siregar in novel’s Azab dan Sengsara, namely sebagai, ibarat, seperti, tak ubahnya, laksana, dan seolah-olah
Analisis Antropologi tentang Konsep "Unnalli Melo"
Authors: Tangibali Dwiwanti Udeng
Published: May 2023

AbstrakMakalah ini adalah hasil pengembangan teori antropologi yang diterapkan pada paham Unnalli Melo dan pengaruhnya terhadap pembentukan karakter masyarakat di Toraja. Kajian ini menyajikan dan memberikan pemahaman yang mendalam tentang konsep antropologi dalam konteks paham Unnalli Melo, serta implikasinya terhadap pertumbuhan dan pembentukan nilai-nilai karakter dalam masyarakat Toraja.
The Metabolic Overdrive Hypothesis. Hyperglycolysis and Glutaminolysis in Bipolar Mania.
Authors: Campbell Iain , Campbell Harry
Published: May 2023

Evidence from diverse areas of research including chronobiology, metabolomics and magnetic resonance spectroscopy indicate that energy dysregulation is a central feature of bipolar disorder pathophysiology. In this paper, we propose that mania represents a condition of heightened cerebral energy metabolism facilitated by hyperglycolysis and glutaminolysis. This unique metabolic state may be initiated in an attempt to restore energy to neurons under conditions of impaired oxidative glucose metabolism occurring in the depressed state.When brain glucose metabolism becomes impaired, neurons can utilize glutamate as an alternative substrate to generate energy through oxidative phosphorylation. Glycolysis in astrocytes fuels the formation of denovo glutamate, which is used as a mitochondrial fuel source in neurons via transamination to alpha-ketoglutarate and subsequent reductive carboxylation to replenish tricarboxylic acid cycle intermediates. Upregulation of glycolysis and glutamate metabolism in this manner causes the brain to enter a state of heightened metabolism and excitatory activity which we propose to underlie the subjective experience of mania.Under normal conditions, this mechanism serves an adaptive function to transiently upregulate brain metabolism in response to demanding mental tasks, a perceived danger or challenge in the environment, or injury. However, when recruited in the long term to counteract impaired oxidative metabolism it may become a pathological process leading to excitotoxicity. In this article, we develop these ideas in detail, present supporting evidence and propose this as a novel avenue of investigation to understand the biological basis for mania.
Ultra-responsive, low-dimensional unfamiliar movement sonification guides unconstrained reaches to invisible targets in 3D space
Authors: Barkasi Michael , Clouser Levi , Harris Laurence
Published: May 2023

Recent studies suggest that artificial auditory feedback, called movement sonification, can function as sensory substitution in motor control, replacing or augmenting vision and proprioception. To a first approximation, studies either apply (1) natural sonifications (exploiting ecological spatial encodings or action-sound associations) of kinematic variables, e.g. velocity, to high (≥3) degree of freedom movements, or (2) nonnatural, i.e. unfamiliar, sonifications including spatial position to low degree of freedom movements. To the best of our knowledge, no one has shown that unfamiliar sonifications of spatial position can be used to guide high degree of freedom movements. We reasoned that an ultra-responsive (1-2ms latency, 1000Hz sampling) sonification compacting 3D spatial information into a low (<3) number of acoustic dimensions would enable spatial guidance of a high degree of freedom movement. We constructed such a movement sonification system using a bespoke digital sound synthesis technique (two-timer pulse-width modulation), real-time time-warping algorithm, and unaligned quaternion representations of body limb rotation. We used the system to sonify unconstrained reaches in space in a way that indicated invisible targets. We validated the system with hardware benchmarking and validated the approach by showing that users were able to reach for targets presented in sonification with approximately half the error of either (a) reaching while listening to qualitatively similar auditory feedback lacking spatial information, or (b) reaching randomly while listening to a constant tone.
Self-acceptance and Purpose in life are Mechanisms Linking Adverse Childhood Experiences to Mortality Risk
Authors: O'Súilleabháin Páraic S , D’Arcy-Bewick Sinéad , Fredrix Milou , McGeehan Máire , Kirwan Emma , Willard Meredith , Miller Amanda A , Sutin Angelina , Turiano Nicholas A
Published: May 2023

Objective: Adverse childhood experiences (ACEs) are associated with increased risk of premature mortality, but it is not clear why. Individuals with ACEs tend to have lower self-acceptance and purpose in life, which may be pathways between ACEs and risk of premature mortality. As such, we tested whether purpose and self-acceptance are mechanisms that link ACEs to mortality risk.Methods: We used the Midlife in the United States Survey (N = 6218; M ± SD = 46.89 ± 12.94 years) to test whether these factors were indirect pathways (mediated) the association between ACEs and mortality hazards over 24 years of follow-up. We employed a comprehensive ACEs measure that included 20 possible childhood adversities including emotional and physical abuse, household instability, socioeconomic climate, and ill health.Results: ACEs significantly increased mortality risk, HR=1.028, 95% CI (1.008, 1.047), p = 0.006. Self-acceptance and purpose accounted for an estimated 15% and 4% of the ACEs-mortality relation respectively. These effects withstood a range of adjustments and sensitivity analyses.Conclusions: ACEs may impact mortality risk partially through lower self-acceptance and purpose during adulthood. Given that self-acceptance and purpose may change through intervention, these factors may be useful targets for individuals with ACEs that could lead to a longer life.
The Importance of Buddhism to Heal Trauma in Pahadi’s “The Tears of Terror”
Authors: Pokharel Badri Prasad
Published: May 2023

This article has tried to analyze Kishor Pahadi’s “The Tears of Terror” by applying Buddhism and its principal assets which would help the victims relieve from the pain and suffering or trauma they have got during the ten-year long Maoist insurgency. People during the decade-long conflict were badly inflicted by the fatal consequences from which they could hardly get over. Different measures were taken to help them get over, however, following some meditative aspects of Buddhism, one can get relief from the mental shock which has been imprinted in mind for a long time. This article is not talking about leaving home and going to the monasteries, rather it highlights some meditative aspects of Buddhism which can relieve the victims who is/are narrated in this story.
Infection Prevention Control (IPC), Hospital acquired infection (HAI) and Obstetrics practice
Authors: Baral Reetu
Published: May 2023

Infection prevention and control program is important to prevent infectious morbidity. Simple method like hand washing to effective sterilization methods are recommended in clinical practice. Immunocompromised state of pregnancy and newborn are more vulnerable to acquire infection; and there is a real challenge from hospital acquired infection because of surgical nature of obstetric care.
Two syringes technique for spinal anesthesia to prevent hypotension in patients undergoing elective cesarean section
Authors: Shrestha Saurav , Pokhrel Jeju Nath , Gurung Tara , Devkota Sagar , Sharma Apurb
Published: May 2023

Aims: To compare the incidence of hypotension after intrathecal administration of hyperbaric bupivacaine and fentanyl in two different syringes against standard injection of mixed fentanyl with hyperbaric bupivacaine.
Methods: This was a prospective comparative study conducted in 174 parturients undergoing elective caesarean section at Paropakar Maternity & Women’s Hospital. Hemodynamic effects and characteristics of block were monitored and recorded and compared between the two groups, group S (single syringe) and group D (double syringe).
Results: The incidence of hypotension was almost similar in the two groups but the drop in systolic blood pressure and mean arterial pressure at 5 minutes and 7.5 minutes after subarachnoid block was significant in group S as compared to group D (p<0.005 and p<0.005 respectively).
Conclusion: Hyperbaric bupivacaine with fentanyl, which when injected separately without mixing, is associated with lesser incidence of hypotension following subarachnoid block.
Correlation between various biochemical biomarkers and blood pressure in pregnant women
Authors: Kaur Balwinder , Renu  , Kumar Ashok , Singh Beant , Kaur Manjit
Published: May 2023

Aims: To find out the correlation of C-reactive protein, serum uric acid and serum LDH with hypertensive antenatal patients.
Methods: The present study was conducted among preeclamptic and eclamptic antenatal patients. Serum was used for estimation of serum levels of CRP, LDH and Uric acid. The data obtained was compiled and analyzed statistically and was expressed in terms of mean±SD and percentage. Student t-test, Chi-square test, Pearson’s Correlation Coefficient were used and p value less than 0.05 was considered significant.
Results: A positive correlation was found between serum CRP level and systolic blood pressure (r = +0.525, P=0.001) & serum CRP level diastolic systolic blood pressure (r= + 0.493, P=0.001). There was a positive correlation between serum uric acid with systolic (r= +0.454, P <0.001) and diastolic blood pressure (r = +0.471, p < 0.001). There was positive correlation between Serum LDH with systolic (r =+0.385, p value of r <0.001) and diastolic BP (r = +0.420, p value of r < 0.001).
Conclusion: Hyperuricemia, increased serum CRP and LDH level can be used as biomarkers for identifying women at risk of preeclampsia and its complications along with adverse effects. We conclude that CRP, serum LDH and Serum Uric acid are reliable and inexpensive markers to predict severity of hypertensive disorders of pregnancy.
Analysis of the phenotypic variants of polycystic ovarian syndrome in women of reproductive age group
Authors: Basnet Pritha , Chhetry Manisha , Shah Deepa , Basnet Tulasa , Sitaula Sarita , Dahal Mona
Published: May 2023

Aims: To identify the different phenotypic variant of PCOS in women of reproductive age group and to assess the hormonal and metabolic profile of women with PCOS.
Methods: This Prospective descriptive study was conducted in the Department of Obstetrics and Gynecology, BPKIHS, Dharan for a period of one year from July 2020 to June 2021. All Women presenting to Gynecology OPD with complaints of menstrual irregularity and clinical features of hyperandrogenism were assessed and evaluated for polycystic ovarian syndrome. BMI was calculated. Hormonal Profile (serum LH, FSH and testosterone) and metabolic parameters (fasting blood sugar and lipid profile) were studied; and then further categorized into different phenotypic variants. All data were stored in Microsoft excel format and analyzed using SPSS version 11.5. using descriptive statistics.
Results: Total of 80 cases of PCOS were enrolled during the study period. The most common phenotypic variant was Type B (60%) followed by Type D (30%). The mean BMI was 22.4± 4.2kg/m2 . All PCOS cases presented with menstrual irregularity as the primary complaint.
Conclusions: Anovulatory PCOS was the most common phenotypic variant in our study population. This study did not find obese PCOS hence emphasizing the need of evaluation in lean women with or without hyperandrogenism presenting with menstrual irregularities.
Konten Instagram: Strategi Kreatif Dana Syariah Dalam Meningkatkan Brand Awareness
Authors: Sachputra Alfian Danang , Muktaf Zein Mufarrih
Published: May 2023

Dana Syariah adalah sebuah perusahaan investasi peer to peer lending yang mem-positioning-kan diri sebagai produk syariah. Sementara itu RWE Digital Agency adalah agensi digital yang mengelola promosi Dana Syariah. Tujuan penelitian ini adalah untuk mengetahui bagaimana strategi kreatif pesan Dana Syariah sebagai produk baru investasi syariah. Penelitian ini mengambil satu platform digital yakni Instagram sebagai platform yang digunakan oleh RWE Digital Agency dalam mempromosikan  produk Dana Syariah. Metode yang digunakan adalah studi kasus melalui wawancara dan penelusuran dokumen. Temuan dari penelitian ini adalah bahwa dalam promosi menggunakan Instagram memiliki 3 pilar utama yakni  Content Strategist, Social Media Officer, dan Monitoring and Report. Pada promosi digital perubahan strategi bisa terjadi ditengah jalan jika tidak sesuai dengan target yang diharapkan.
Studi Etnografi Komunikasi Komunitas Penutur Bahasa Inggris Non-Native Speakers di Bandung
Authors: Usman Ari
Published: May 2023

Pentingnya bahasa Inggris telah mendorong Komunitas Ngabrink di Kota Bandung untuk menyelenggarakan program diskusi mingguan English Talk bagi masyarakat umum. Diskusi berlangsung dalam bahasa Inggris, meskipun para partisipannya bukanlah penutur asli bahasa tersebut. Sebagai bagian dari masyarakat tutur Inggris-Indonesia, peserta English Talk berkomunikasi dalam bahasa Inggris menurut kaidah dan variasi linguistiknya sendiri yang khas. Maka tujuan dari penelitian ini adalah untuk mengetahui bagaimana pola komunikasi yang terbentuk selama berlangsungnya kegiatan English Talk tersebut. Penelitian ini menggunakan metode kualitatif dengan pendekatan etnografi komunikasi. Pengumpulan data diperoleh melalui observasi dan wawancara mendalam. Informan penelitian terdiri dari Ketua Komunitas Ngabrink sebagai gatekeeper dan informan kunci, serta dibantu empat orang member lainnya. Hasil penelitian menunjukkan bahwa situasi komunikasi berupa diskusi kelompok membahas topik-topik yang dielaborasi menjadi tiga pertanyaan yang bertujuan agar member berani berbicara dalam bahasa inggris. Diskusi berlangsung secara kasual dan egaliter mengingat usia dan skema kognitif peserta yang relatif sama. Peserta diskusi juga berkomunikasi secara verbal dan nonverbal. The importance of mastering English language has motivated the Ngabrink Community in Bandung to initiate a weekly discussion program named English Talk. Discussion is conducted in English, even though all participants are not native speakers. As a part of English-Indonesian speech community, they have their own linguistic rules and varieties in communicating. So the aim of this research is to discover the communication pattern that is constructed during the English Talk activity. This study uses qualitative method with ethnography of communication approach. Data gathered by observation and in-depth interview. Informants in this research are: the chairman of Ngabrink Community as key informant and four other members. The result shows that communication situation in format of group discussion that discuss a topic elaborated into three discussion questions, intended for participants to talk confidently in English. They discuss in casual and egalitarian way, because they are almost in the same age and cognitive schema. Participants also communicate verbally and nonverbally.
Amplifikasi Budaya Pop Bonge-Jeje Melalui Media Sosial Tik Tok
Authors: Irwanto Irwanto , Hariatiningsih Laurensia Retno
Published: May 2023

Bonge-Jeje dan rekan-rekannya berhasil menarik perhatian publik melalui budaya pop yang mereka sebarkan. Pada awalnya penampilan mereka dikenal melalui media sosial TikTok. Keunikan dari pakaian yang mereka kenakan pada awal kemunculannya di TikTok adalah pakaian yang tidak bermerek, tidak mahal dan cenderung tidak lazimnya seperti pakaian pada umumnya. Penelitian ini bertujuan mendeskripsikan fenomena budaya pop ala Eka Satria Saputra alias Bonge dan Jeje dikomunikasikan dan dikenal serta diterima masyarakat melalui media sosial Tik Tok. Disini juga akan diurakan faktor-faktor yang dapat membuat masyarakat menerima budaya pop mereka. Untuk mengetahui elemen-elemen tersebut, penelitian ini menggunakan metode kualitatif dengan paradigma konstruktivis. Ditemukan bahwa Bonge-Jeje dan rekan-rekannya melakukan konstruksi terhadap konten budaya pop yang mereka sebarkan. Konstruksi tersebut dimulai dari pemilihan media sosial, elemen visual, elemen audio dan gimmick.
Pencarian Criteria Splitting Terbaik Pada Algoritma C4.5 Untuk Mengukur Pemilihan Pembelajaran Pada Era Pendemi Covid-19
Authors: Masripah Siti , Nurwulandari Dewi Ayu , Saputra Rizal Amegia
Published: May 2023

Kondisi pandemi tahun 2022 masih berlangsung dan sudah memasuki tahun ke-2 sistem pembelajaran yang dilakukan masih belum 100% luring dan masih dilakukan secara daring. Sistem pembelajaran yang dilakukan secara daring tentunya membuat para orang tua, pendidik serta pelajar harus mengeluarkan biaya ekstra dan pemahaman yang ekstra karena tidak semua mampu mengatasi dua hal tersebut. Klasifikasi dalam menentukan pemilihan pembelajaran menjadi sangat penting, karena pembelajaran daring menuai pro dan kontra pada tengah masyarakat. Pada penelitian ini dataset didapat dari hasil survei terhadap orang tua, pendidik, siswa serta mahasiswa, dan sebanyak 283 responden telah terkumpul untuk mengukur pemilihan pembelajaran pada Era Pandemi Covid-19. Pengolahan data dilakukan dengan menggunakan aplikasi Rapid miner dan menerapkan metode Algoritma Klasifikasi Data Mining C4.5, dalam proses eksperimen dilakukan proses komparasi kriteria split pada algoritma C4.5 yaitu Information Gain, Gini Index Dan Gain Ratio. Diperoleh dua nilai yang paling tinggi nilai akurasinya yaitu sebesar  85.88% untuk Gain Ratio dan Information Gain, sementara untuk Gini Index sebesar 8.24%. Untuk nilai AUC yang paling tinggi yaitu 0.80 pada Gain Ratio, disusul oleh Information Gain sebesar 0.783 dan Gini Index sebesar 0.784. Berdasarkan hasil komparasi kriteria Split gain ratio termasuk kategori klasifikasi Baik, dikarenakan memiliki nilai diantara 0.80 – 0.90.
Information Retrieval Pemetaan Peta Jalan Penelitian Perguruan Tinggi Berbasis Dokumen Publikasi Ilmiah Dosen
Authors: Wibowo Agung , Wajhillah Rusda
Published: May 2023

Kualitas penelitian perlu diarahkan dan diklasifikasikan untuk perbaikan. Roadmap perguruan tinggi harus sesuai dengan minat dan keahlian dari dosennya. Oleh karena itu, menjadi kewajiban setiap perguruan tinggi untuk membuat perencanaan strategis dan riset unggulan. Fakultas Teknologi Informasi di hampir semua perguruan tinggi telah menghasilkan banyak publikasi ilmiah. Dokumen publikasi karya ilmiah merupakan salah satu contoh dokumen tidak terstruktur. Isinya berupa gaya penulisan, sebagian besar ditentukan oleh bahasa pengarang. Umumnya, judul dokumen hanya menentukan jumlah kata maksimal. Tujuan utama dari information retrieval system adalah untuk menentukan kata kunci dokumen dari query yang diberikan oleh pengguna dalam sekelompok dokumen. Algoritma TF/IDF (Term Frequency – Inversed Document Frequency) dan Algoritma Vector Space Model adalah beberapa metode dari algoritma yang dapat memanfaatkan text mining dalam menganalisis tahapan sebagai opsi penentuan klasifikasi dokumen berdasarkan kata-kata solusi yang sering muncul pada judul dokumen. Makalah ini dapat membantu para pengambil keputusan untuk menentukan, menilai, mengadaptasi roadmap penelitian ke perguruan tinggi. Penggambaran model pohon menggunakan roadmap jangka panjang membuatnya lebih mudah dibaca dan dipahami.
Analisis Kesehatan Bank Umum Syariah Berdasarkan Metode RGEC terhadap Profitabilitas di Indonesia
Authors: Nasir Muhammad , Safaruddin Safaruddin , Prihatin Nanang , Humaira Filza , Abdullah Hasyimi
Published: May 2023

Tujuan penelitian ini untuk memperoleh jawaban tentang kondisi kesehatan Bank Umum Syariah (BUS) menggunakan metode RGEC (Risk Profile, Good Corporate Governance, Earnings, Capital) di Indonesia serta pengaruhnya terhadap profitabilitas. Ukuran profil risiko menggunakan NPF, earnings dengan BOPO, dan modal dengan CAR sedangkan profitabilitas dengan ROA. Pengamatan dilakukam selama 20 triwulan mulai Maret 2016 hingga Desember 2020. Data terutama diperoleh dari Otoritas Jasa Keuangan berupa data sekunder. Populasi berjumlah 13 BUS, dan penarikan sampel menggunakan kriteria tertentu sehingga didapatkan 5 BUS sebagai sampel. Model analisa yang dipakai ialah regresi linear berganda data panel. Penentuan model terbaik didapatkan dari Uji Chow, Hausman, serta Langrange Multiplier. Hasil uji merekomendasikan Fixed Effect Model sebagai model terbaik. Hasil statistik deskriptif menyimpulkan secara umum kesehatan bank berada pada kriteria sehat. Uji simultan menghasilkan NPF, GCG, BOPO dan CAR signifikan berpengaruh terhadap profitabilitas BUS di Indonesia. Uji parsial merekomendasikan  BOPO dan CAR signifikan,  sedangkan  NPF serta GCG tidak signifikan pengaruhnya
Pengaruh Corporate Governance Terhadap Nilai Perusahaan Dengan Ukuran Perusahaan dan Return On Assets Sebagai Variabel Kontrol
Authors: Annisa Ayu Suci , Wulandari Ika , Utami Endang Sri , As’ari Hasim
Published: May 2023

Penelitian ini bertujuan untuk mengetahui pengaruh good corporate governance terhadap nilai perusahaan dengan ukuran perusahaan dan Return on Assets sebagai variabel kontrol pada Badan Usaha Milik Negara yang terdaftar di Bursa Efek Indonesia periode 2020–2021. Penelitian ini menggunakan teori stakeholder.  Secara umum, good corporate governance adalah sebuah sistem, struktur, dan mekanisme yang dibentuk untuk mencapai keberhasilan suatu perusahaan dan nilai perusahaan adalah gambaran dari kepercayaan masyarakat terhadap keberhasilan perusahaan yang biasanya dikaitkan dengan harga saham perusahaan. Nilai perusahaan sebagai variabel dependen diukur menggunakan Tobin’s Q. Variabel independen yang digunakan dalam  penelitian adalah keberadaan komisaris wanita, komisaris independen, dan  kepemilikan institusional. Variabel kontrol dalam penelitian ini, ukuran perusahaan dan Return on Assets. Sampel yang digunakan dalam penelitian diambil dengan menggunakan metode purposive sampling dengan 16 perusahaan yang merupakan Badan Usaha Milik Negara. Penelitian ini menggunakan analisis regresi data panel. Hasil penelitian menunjukkan bahwa komisaris independen dan kepemilikan institusional berpengaruh positif terhadap nilai perusahaan, namun keberadaan komisaris wanita tidak berpengaruh terhadap nilai perusahaan. Variabel kontrol ukuran perusahaan dan Return on Assets tidak berpengaruh terhadap nilai perusahaan.