bluuebunny/crossref_metadata_2025 huggingface dataset:
Pharmacological properties of new chalcones for treatment of leishmaniasis: in silico and in vitro studies
Authors: Silva Gleice Rayanne , Leite Fernando Ferreira , Acevedo Chonny Alexander Herrera , Santos Francisnaira Silva , Grimaldi Gabriela Bittencourt , Soares Milena Botelho Pereira , Guimarães Elisalva Teixeira , Scotti Marcus Tullius , Rodrigues Luis Cezar , Campana Eloísa Helena , Guimarães Hemerson Iury Ferreira , Guerra Felipe Queiroga Sarmento
Published: June 2023

Leishmaniasis constitutes a complex of endemic and neglected diseases with high morbidity and mortality rates. Due to the toxicity, resistance profile and adverse effects of current drugs, science is looking for new therapeutic alternatives. Therefore, the objective of this study was to investigate in silico and in vitro tests the leishmanicidal potential of chalcones and verify their influence on the production of Reactive Oxygen Species (ROS). For the in silico tests, the PASS filter program was used. Murine macrophages (J774) and promastigotes and amastigotes of Leishmania braziliensis were used for in vitro tests. The selectivity index (SI) was calculated through the ratio between the 50% cytotoxicity concentration value (CC50) and the 50% inhibitory concentration value (IC50). Evaluation of ROS levels were obtained using the reagent 2'7'-dichlorodihydrofluorescein diacetate (H2DCFDA). The results indicated that one of the biological activities most associated with flavonoids is the antileishmanial activity. All chalcones tested did not show significant cytotoxicity and the chalcone that showed the best antileishmanial potency was compound 4 (FERAI), with a CI50 of 9.75 ± 1.7 µM and 10.13 ± 1.7 µM for promastigotes and amastigotes of L. braziliensis, respectively. Macrophages treated with FERAI showed a reduction in infection and amastigotes number. FERAI has been shown to increase ROS levels, which is one of its possible mechanisms of action against the parasite. In view of the observed results, it is concluded that all compounds did not exhibit significant cytotoxicity and FERAI presented itself as a strong candidate for a new drug against leishmaniasis.
A Novel Approach for Credit Card Fraud Transaction Detection Using Deep Reinforcement Learning Scheme
Authors: Qayoom Abdul , Khuhro Mansoor Ahmed , Kumar Kamlesh , Waqas Muhammad , Saeed Umair , Wu Yadong , Wang Song , Ur-Rehman Shafiq
Published: June 2023

Online transactions are the backbone of the financial industry globally. Millions of people are using credit cards daily, which has led to an exponential rise in their daily life that has led to an exponential rise in credit card frauds. With the passage of time, many variations and schemes of fraudulent transactions have been occurring. Real-time credit card fraud detection is still a challenging task. Every person has a unique transaction pattern. This pattern may vary over a period of time. Sometimes, credit card frauds have no constant pattern. This paper aims to 1) understand how deep reinforcement learning can play a vital role in detecting credit card fraud and 2) design solution architecture for real-time detection. Our proposed model uses the DeepQ network. A deep Q network has been utilized for real time detection. The online available Kaggle dataset hasbeen used for model training and testing, and 97% validation performance has been achieved via our proposeddeep learning component. The reinforcement learningcomponent has an 80% learning rate. Our proposedmodel was able to learn patterns itself based on previous history and adopted the pattern changes over timeand accommodate them without any further manualtraining.
An empirical model for branding oriented by the environmental sustainability of the Amazon Rainforest - A hybrid structural equation modeling with fsQCA approach
Authors: Santos Luiz Diego Vidal , Holanda Francisco Sandro Rodrigues , Pedrotti Alceu , de Medeiros Raphael Mario Bastos , Oliveira Catuxe Varjão de Santana , Villwock Ana Paula Schervinski
Published: June 2023

Using the theory of planned behavior, it is possible to establish a valuable connection between an organization and its consumers, which goes beyond appearance and involves emotions, relationships, and experiences with the brand. Based on these principles, the objective of this work was to present an empirical model guided by empirical evidence from the perception of entrepreneurs and consumers of brands related to environmental sustainability in the Brazilian Amazon. The proposed model uses mixed modeling, based on data analysis based on fuzzy-set qualitative comparative analysis (fsQCA), using two sets of data from independent research obtained from 8 companies operating in the Amazon rainforest and 535 potential consumers. Based on the observed data, the consumers' motivations for consumption, the practices adopted by entrepreneurs, and the role of traditional communities and the forest environment in the brand's conception were identified. The results show that for the interest in purchasing sustainable brands to be positive, from the perception of consumers, the brand must explore information regarding involvement with traditional communities, perception of brand quality, and brand innovation, also making clear the positioning strategy adopted since the constructs are central to the main solution. This article presents relevant information for entrepreneurs of sustainable brands in tropical forests, business policymakers in community-based entrepreneurship, researchers, and those interested in brand management as a strategy to boost small businesses with sustainable practices and involvement with traditional communities. The study's findings and recommendations can promote more sustainable and socially responsible business practices, strengthening the local economy and contributing to environmental preservation.
Gold nanowires based on photonic crystal fiber by laser ablation in liquid to improve colon biosensor
Authors: Fakhri Makram A. , Salim Evan T. , Sulaiman Ghassan M. , Albukhaty Salim , Ali Hiyam S. , Salim Zaid T. , Gopinath Subash C.B. , Hashim Uda , Al-aqbi Zaidon T.
Published: June 2023

In this work, gold nanoparticles have been synthesized using second harmonic generation ND-YAG laser ablation in Ethanol employing 532 nm and 1.064 nm wavelengths. Field emission scanning electron microscope (FESEM), Transmission electron microscopy (TEM)X-Ray diffraction (XRD), Atomic force microscopy (AFM), photoluminescence (PL) spectroscopy, and UV–Vis absorption were employed to examine the structural, chemical and optical properties of Au NPs. XRD results showed that all synthesized Au nanoparticles are crystalline in nature. the optical band gap upon ablation using the higher wavelength (1064 nm) was about (4.02 eV). While the value of the optical bandgap increases to reach a value of (4.22 eV) at the shorter wavelength (532 nm The FESEM results reveal the formation of smaller nano rode size at second-harmonic generation (SHG) wavelength was found to be about (30 nm at wavelength 532 nm and 44 nm at 1064nm). After that, Finite Element Analysis is used to simulate the photonic crystal fiber (PCF) as biosensors, depending on the surface Plasmon resonance (SPR) phenome-non using COMSOL Multiphasic program. The hollow core-photonic crystal fiber (HC-PCF) HC-800 was thus overfilled with (water). The confinement loss (CL) of the fundamental mode for the proposed PCF with and without the gold nanoparticles was calculated, we observe without gold NPs the CL at the water and Colon tissue about (1.08E+03, 5.46E+02) dB/m, while at use the deposited PCF with gold NPs the results ensured the decrease more than in the confinement loss at the water and Colon tissue about (1.01E+03, 3.16E+02) dB/m with a clear shift toward higher wavelengths, also when calculating the sensitivity, to increase HC-PCF bio-sensor performance by using wavelength interrogation and amplitude measurements, it found the bio-liquid (colon tissue) has the best electric field using the gold NWs layer in the biosensor equal to 68.8 V/m by comparison when without using the gold NWs layer which leads to high sensitivity.
A comparative study of machine learning approaches to heart disease prediction: an empirical analysis
Authors: Hidayaturrohman Qisthi Alhazmi , Clarke Hulya Gokalp , Taflan Gaye Yesim , Sancaktar Idris
Published: June 2023

Purpose:
This paper compares five supervised learning algorithms (support vector machines, k-nearest neighbor, decision tree, random forest, and AdaBoost) for predicting heart disease and examines the impact of normalization and GridSearch hyper-parameter tuning on model performance.
Methods:
The study utilizes the Cleveland database from the University of California-Irvine (UCI) repository, comprising data on 918 instances of heart disease patients with 12 attributes. Eleven attributes serve as predictors, while one attribute represents the target class. Models are built and tested using this dataset.
Results:
Comparing the algorithm performances with existing literature, accuracies range from 89.13–91.85%. AdaBoost exhibits the highest performance, whereas the decision tree performs the least effectively. Results surpass those reported in the literature. Normalization improves prediction performance by 17% for Support Vector Machines (SVM) and 14% for k-nearest neighbor (kNN). SVM does not benefit from GridSearch, while GridSearch enhances the decision tree and AdaBoost by 7% and 4% respectively. Normalization combined with GridSearch improves kNN and random forest by 2–3%.
Conclusion:
This study compares supervised learning algorithms for heart disease prediction. AdaBoost emerges as the top-performing algorithm, while the decision tree performs relatively poorly. The findings surpass those in the literature. Normalization significantly improves performance for SVM and kNN, while GridSearch enhances the decision tree and AdaBoost. Combined, normalization and GridSearch yield performance improvements for kNN and random forest. These results contribute to the field of heart disease prediction, offering valuable insights for algorithm selection and guiding future research.
Frame Duplication and Insertion Forgery Detection in Surveillance Videos Using Optical Flow and Texture Features
Authors: Akhtar Naheed , Hussain Muhammad , Habib Zulfiqar
Published: June 2023

Surveillance cameras are widely used to provide protection and security through online tracking or investigation of stored videos of an incident. Furthermore, footage of recorded videos may be used as strong evidence in the courts of law or insurance companies, but their authenticity cannot be taken for granted. Two common video inter-frame forgery types are frame duplication (FD) and frame insertion (FI). Several techniques exist in the literature to deal with them by analyzing the abnormalities caused by these operations. However, they have limited applicability, poor generalization, and high computational complexity. To tackle these issues, we propose a robust hybrid forensic system based on the idea that FD or FI causes motion inconsistency at the start and end of duplicated/inserted frames. These inconsistencies, when analyzed in an appropriate manner, help reveal the evidence of forgery. The system encompasses two forensic techniques. The first is a novel method based on the texture of motion residual component where a motion residual-based local binary pattern histogram (MR-LBPH) and an SVM classifier with the linear kernel are employed to detect suspected tampered positions. The second component is the sum consistency of optical flow (OF) and standard deviation of MR-LBPH of consecutive frames to remove false positives and precise localization of forgery. By taking the intersection of the frames detected by the two methods, we remove the false positives and get the frames bounding the duplicated/inserted region. The methods were trained and tested on our developed large Video Tampering Evaluation Dataset (VTED) and cross-validated on publicly available datasets. Cross-dataset evaluation yielded detection accuracy above 99.5%, ensuring the proposed method’s generalization; it also precisely locates the locations of tampering. As the public datasets used for cross-dataset validation include videos of different formats and frame rates, it ensures the wide applicability of the method. Moreover, the method is computationally efficient and can be run in a matter of microseconds.
A Comparison of the Surface Water Quality in Distinct Areas of The Southern Black Sea Coast under Various Pressures
Authors: TAN İbrahim , ATABAY Hakan , MUTLU Sabri , TOLUN Leyla Gamze , BEKEN Sevcan Çolpan POLAT
Published: June 2023

The Black Sea is a significant European watershed, more productive than the nearby Mediterranean, with dynamic wetland habitats along the shore and at the river mouths. Seasonal dynamics that sustain food webs that are adapted to the brackish, nutrient-rich environments are determined by the physiochemical conditions. River discharges carry phosphorus and nitrogen ions with high molar ratios into the Black Sea coasts. The present study evaluated the variations in water quality parameters between the winter season of 2020 and summer season of 2019 at 54 stations representing the two major rivers mounts (the Sakarya and Yeşilırmak), Samsun’s port and urban wastewater treatment outflow. Yeşilırmak River showed much higher nitrogen concentrations in the winter (̴ 1.46 µM) compared to the summer (̴ 0.10 µM). In addition, the Sakarya River nitrogen concentrations were similar between winter and summer seasons. The total phosphorus (̴ 2.25 µM) and chlorophyll-a (̴ 6.36 µg/L) concentrations were high at Samsun stations in the summer season 2019, where the pressure of urban wastewater is significant. The state of pollution, the sources of pollution, and their quantitative contributions in river basins and coastal regions must be determined for effective pollution control and water resource management.
A targeting nanoplatform for chemo-photothermal synergistic therapy of small-cell lung cancer
Authors: Yin Moli , Liu Lei , Yan Yu , Wang Huiyan , Li Wenliang , Dong Yuan , Kong Guangyao
Published: June 2023

The chemo-photothermal cotherapy has created a breakthrough in cancer treatment, but the precise delivery of drugs to tumor sites and the thermoresistance of tumors remain major challenges in photothermal therapy (PTT). Due to its overexpression in small cell lung cancer (SCLC) and limited normal tissue expression, Somatostatin receptor 2 (SSTR2) is proposed as an ideal target for the precise treatment of SCLC. We first developed a novel anti-SSTR2 monoclonal antibody (MAb), which showed strong and specific affinity toward SSTR2 receptor overexpressed on SCLC cells. Then, a targeting nano-drug delivery system comprising anti-SSTR2 MAb surface-modified poly (lactic-co-glycolic acid) (PLGA) nanoparticles co-encapsulating Cypate and gambogic acid (GA) is prepared for achieving specific tumor targeting and chemo-photothermal combination therapy. The formed SGCPNs nanoparticles demonstrated excellent monodispersity, physiological stability, preferable biocompatibility, and resultant efficient photothermal conversion efficacy. Confocal microscopy images showed that SGCPNs were quickly internalized by SSTR2-overexpressing SCLC cells, triggering the release of GA under acidic and near-infrared (NIR) laser irradiation environments, leading to their escape from lysosomes to the cytosol and then diffusion into the nucleus. At the same time, GA molecules can not only decrease the cell survival rate but also inhibit the activity of HSP90 to enhance PTT efficacy. SGCPNs can be precisely delivered to xenograft tumors of SSTR2-positive SCLC in vivo and decrease the undesirable effects on healthy organs. Upon NIR laser irradiation, therapy of SGCPNs showed significant tumor regression. In conclusion, SGCPNs provide a new chemo-photothermal synergistic treatment strategy for targeting SCLC.
D-amino acids trigger an inflammatory environment in vitro: potential role in modulating age-associated inflammation
Authors: Yap Siew Hwei , Lee Cheng Siang , Zulkifli Nur Diyana , Suresh Darshinie , Hamase Kenji , Das Kumitaa Theva , Rajasuriar Reena , Leong Kok Hoong
Published: June 2023

Studies in vivo have demonstrated that the accumulation of D-amino acids (D-AAs) is associated with age-related diseases as well as increased immune activation. However, the underlying mechanisms are not well defined. The metabolism of D-AAs produces hydrogen peroxide (H2O2), a reactive oxygen species that involves several physiological processes including immune response, cell differentiation and proliferation. Excessive levels of H2O2 contributes to oxidative stress and eventually causes cell death, a characteristic of age-related pathology. We explored the molecular mechanisms of D-serine (D-Ser) and D-alanine (D-Ala) in human liver cancer cells, HepG2 cells, with attention to the production of H2O2, due to the oxidation of D-AAs by D-amino acid oxidase (DAO), and secretion of pro-inflammatory cytokine and chemokine, which subsequently leads to inflammation and cell death. In HepG2 cells, we demonstrated that D-Ser decreased H2O2 production and induced concentration-dependent depolarization of MMP, with upregulation of activated NF-кB and pro-inflammatory cytokine, TNF-α, and chemokine, IL-8, which subsequently led to apoptosis. Conversely, D-Ala-treated cells induced H2O2 production, accompanied by the upregulation of activated NF-кB, TNF-α and IL-8, but did not cause significant apoptosis. The present study confirms to the role of both D-Ser and D-Ala in inducing inflammatory responses but each via unique activation pathways. This response was associated with apoptotic cell death only with D-Ser. Further research is required to gain a better understanding of the mechanisms underlying inflammation induced by D-AAs and downstream consequences especially in the context of aging given the wide detection of these entities in systemic circulation.
Epigenetic regulation of co-transcriptional R-loops via IGF2BPs drives SEMA3F-mediated prostate cancer growth retardation and docetaxel chemosensitivity enhancement
Authors: Ying Yufan , Tang Yijie , Wu Yuqing , Yi Jiahe , Liu Zixiang , Ma Xueyou , Fang Jiajie , Li Jiangfeng , Chen Danni , Wang Xiao , Liu Xiaoyan , Liu Ben , Luo Jindan , Zheng Xiangyi , Xie Liping
Published: June 2023

R-loops are prevalent three-stranded nucleic acid structures, comprising a DNA-RNA hybrid and a displaced single-stranded DNA, that frequently form during transcription and may be attributed to genomic stability and gene expression regulation. It was recently discovered that RNA modification contributes to maintain the stability of R-loops such as N6-methyladenosine (m6A). Yet, m6A-modified R-loops in regulating gene transcription remains poorly understood. Here, we demonstrated that insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) recognize R-loops in an m6A-dependent way. Consequently, IGF2BPs overexpression leads to increased overall R-loop levels, cell migration inhibition, cell growth retardation and docetaxel chemosensitivity in prostate cancer (PCa) via precluding the binding of DNA methyltransferase 1(DNMT1) to semaphorin 3F (SEMA3F) promoters. Moreover, the K homology (KH) domains of IGF2BPs are required for their recognition of m6A-containing R-loops and are required for tumor suppressor functions. Our findings point to a distinct R-loop resolution pathway mediated by IGF2BPs, emphasizing the functional importance of IGF2BPs as epigenetic R-loop readers in transcriptional genetic regulation and cancer biology.
Recent Advances and Prospective on the effect of processing parameters, additives, and applications of silica aerogel nanocomposites
Authors: Jadhav Sapna B. , Sarawade Pradip B.
Published: June 2023

Silica Aerogels have emerged as a new class of porous solid-state nanomaterials which consist of a three‐dimensional (3D) solid silica network with a huge air-filled space of highly cross-linked structures. Due to the distinct features, such as high porosity, large surface area, extremely low density, and low thermal conductivity, they show potential applicants in various emerging fields. Silica aerogel limits its application due to its fragile nature; as a result, it is essential to develop mechanical strength. To enhance the widespread industrial application of silica aerogel in the future, reinforcement of fiber/polymer/metal oxide has been widely studied. This overview particularly emphasizes achieving mechanisms of mechanical strength on the recent advances regarding various additives into the silica matrix. Also, the outline of the significant improvements in the resultant mechanical strength, thermal conductivity, porosity, and surface area of the nanocomposites are represented. In this review, we have elaborated on the synthesis of the silica aerogel, fillers trapped inside the silica matrix aerogel pores, and its application in potential fields.
Numerical Analysis of Prey Refuge Effects on the Stability of Holling Type III Four-Species Predator-Prey System
Authors: Odhiambo Francis , Aminer Titus , Okelo Benard , Manyala Julius
Published: June 2023

The dynamic behavior of a multi-species system that includes a prey refuge and a Holling type III functional response is examined in this work. The pre-requisites for the presence of the equilibrium points, as well as their local and global stabilities, for the suggested system are analyzed and derived. The Routh-Hurwitz criterion and the eigenvalue technique are used to study the local stabilities. On the other hand, the global stabilities have been studied using the Lyapunov technique. Numerical simulations have been carried out using the Matlab ode45 solver software to verify the analytical results. The findings show that refuge plays a significant part in improving the dynamical stability of the system.
Assessment of the association between D-dimer levels and clinicopathological characteristics of pancreatic cancer and its role in prognosis: a systematic review and meta-analysis
Authors: wu bin , Zhang ming guang , Zhao shuang xia , Wang jie , Wang da , Zhang peng yi , Yu Miao , Cai hui
Published: June 2023

Background: According to previous studies, D-dimer levels are associated with prognosis in patients with pancreatic cancer (PC). However, the current results are limited and controversial. Therefore, we conducted this meta-analysis to assess the relationship between D-dimer levels and the prognosis and pathological characteristics of patients with PC.
Method: A computer search of PubMed, Embase, The Cochrane Library, Web Of Science, CBM, VIP, CNKI and Wanfang databases was conducted to identify available studies. The association between pre-treatment d -dimer levels and the prognosis of PC patients was assessed using a combined hazard ratio (HR) and 95% confidence interval (CI). The combined odds ratio (OR) and 95% confidence in CI were applied to assess the relationship between D-dimer levels and the pathological characteristics of patients with PC. For all of the statistical analyses, Stata 12.0 software was used.
Result: A total of 13 studies involving 2777 patients were included in this meta-analysis. The results showed that elevated pre-treatment d -dimer levels were significantly associated with worsening OS (HR = 1.46 95% CI: 1.34-1.59; p＜0.001). We also performed subgroup analyses based on sample size, d -dimer threshold, follow-up time and source of HR to further validate the prognostic value of pre-treatment d -dimer levels in PC. In addition, according to the analysis, high pre-treatment d -dimer levels in PC patients were associated with late tumour stage (OR = 4.78, 95% CI 1.73-13.20, p＜0.005), larger tumours (OR = 1.72, 95% CI 1.25 ~ 2.35, p＜0.005) and distant metastases in tumours (OR = 5.06, 95% CI 2.45- 10.43, p＜0.005) were significantly associated. In contrast, other clinicopathological factors, including age, sex and lymph node metastasis, were not associated with d -dimer levels.
Conclusion: High levels of d-dimer prior to treatment are associated with poor prognosis in patients with PC and are associated with more advanced tumour stage, larger tumours and the occurrence of distant metastases. Plasma d-dimer levels can be used as a biomarker of prognosis in patients with PC.
Quantum local random networks and the statistical robustness of quantum scars
Authors: Surace Federica Maria , Dalmonte Marcello , Silva Alessandro
Published: June 2023

We investigate the emergence of quantum scars in a general ensemble of random Hamiltonians (of which the PXP is a particular realization), that we refer to as quantum local random networks. We find a class of scars, that we call “statistical”, and we identify specific signatures of the localized nature of these eigenstates by analyzing a combination of indicators of quantum ergodicity and properties related to the network structure of the model. Within this parallelism, we associate the emergence of statistical scars to the presence of “motifs” in the network, that reflects how these are associated to links with anomalously small connectivity. Most remarkably, statistical scars appear at well-defined values of energy, predicted solely on the base of network theory. We study the scaling of the number of statistical scars with system size: by continuously changing the connectivity of the system we find that there is a transition from a regime where the constraints are too weak for scars to exist for large systems to a regime where constraints are stronger and the number of statistical scars increases with system size. This allows to define the concept of “statistical robustness” of quantum scars.
The Mustang Diaries: un estudio de México en Red Dead Redemption 1
Authors: Aldape Javier
Published: June 2023

¿Será posible usar el juego para mostrar el pasado en la cultura popular? ¿Podrá una persona realizando tal acto adquirir agencia sobre un tiempo particular de la historia? El juego se define de distintas maneras—pero para el propósito de este trabajo, se usará dentro del contexto de videojuegos. Usando las dos ideas principales sobre el estudio de estos: La narratología y la ludología, intento resaltar el potencial de los juegos no solo para recrear la historia, sino para interactuar con los eventos con el fin de mostrar cómo pueden prestar nuevas maneras de entender la historia. Me concentraré particularmente en el periodo de la revolución mexicana dentro del juego western de Rockstar Games, Red Dead Redemption 1.
La escena de la música rock en la frontera entre Estados Unidos y México: traducción y adaptación cultural
Authors: Sánchez José , Soto-Vázquez Arthur
Published: June 2023

Este estudio aborda cómo la música rock se integró en la cultura local de una región donde los géneros musicales dominantes eran el tejano y otras formas de inﬂuencia mexicana. Usando una serie de entrevistas cualitativas y profundas con músicos de larga práctica, discutimos cómo se formó el rock y cómo se mezcló con las costumbres y prácticas locales. Los músicos hablaron sobre ser ﬂexibles en sus presentaciones en vivo, tocar canciones de la invasión británica justo después de un corrido, ser marginados y actuar en ranchos fuera de los límites de la ciudad cuando los clubes no los presentaban. Sin embargo, la escena de la música rock local se desarrolló en el sur de Texas y se convirtió en un híbrido cultural único. Usamos este ejemplo para discutir cómo se ve la hibridez cultural en el contexto de la interpretación musical, el papel de los nuevos medios en su avance y lo que significa para la  identidad fronteriza.
Explorando la afectividad, la identidad y el populismo en torno a Joker (2019) de Todd Phillips
Authors: Sreepada Nihar , Domínguez Partida Gabriel
Published: June 2023

La identidad cultural se ha convertido en un concepto ﬂuido en el que convergen varias posiciones; la mayoría de ellas están fuertemente inﬂuenciados por la cultura popular, provocando una constante negociación individual entre la vida real y la imagen en la pantalla. En 2019, Joker de Todd Phillips logró el éxito mundial no solo en la taquilla sino también en la evaluación crítica. A diferencia de las  representaciones anteriores de este villano como un personaje social disruptivo, Joker mostró al personaje principal como una figura política que da voz y agencia a las personas socialmente reprimidas. El impacto de esta representación trascendió las culturas anglosajonas hasta el punto de simbolizar un levantamiento populista y un creciente sentimiento antigubernamental. Sin embargo, la apropiación de esta figura trae dos puntos de vista ideológicos problemáticos al objetivo que persiguen estos grupos: la violencia como única alternativa para restaurar la igualdad en la sociedad y el daltonismo que silencia las luchas que enfrentan las culturas según su contexto.
Türk İslam Sanatında Seccade Kültürü ve Antalya Çevresinde Tespit Edilen Seccade Dokumaları
Authors: Eroğlu Mehmet Ali
Published: June 2023

Binlerce yıllık kültür ve sanat geçmişi olan Türk sanatında dokumaların yeri ve önemi oldukça büyüktür. El dokuma literatüründe önemli bir yere sahip olan dokuma örneklerinden birisi de seccadelerdir. İslamiyet ile Türk kültür ve sanatına dahil olan; seccade, namazlağ yada namazlık gibi isimlerle anılan bu dokumalar, Anadolu insanı için dini nitelikler taşıyan yaygılardır.
Diğer dokuma örneklerinde olduğu gibi seccade dokuma örnekleri de kaybolma tehlikesi ile karşı karşıyadır. Bunun başlıca sebepleri olarak; yörüklerin yerleşik yaşama geçmeleri ve el dokuması ürünlerin yerini fabrikasyon ürünlerin alması gösterilebilir. Bu bağlamda; Antalya/Döşemealtı, Manavgat, Akseki ve Antalya/Kaleiçi bölgelerinde 2011-2014 tarihleri arasında alan araştırmaları yapılmıştır.
Araştırma kapsamında 80 civarı örnek incelenmiş olup, incelenen örneklerle bağlantılı literatür bilgileri taranmış, kaynak kişilerden elde edilen bilgiler literatürdeki bilgiler ile karşılaştırılarak desteklenmiştir.
Bu çalışmada; Kaleiçi’nde, halı, kilim ve benzeri el dokuması koleksiyonerlerinde bulunan, farklı yörelere ait 10 adet seccade (namazlağ) dokuma örneği; desen, renk, hammadde, dokuma teknikleri ve kompozisyon özellikleri açısından incelenmiştir.
Denizli Tekkeköy Termal Çamuru ve Bölge Kilinin Seramik Bünyede Kullanımı
Authors: Kılıç Atilla Cengiz , Çam Ayşen
Published: June 2023

Öz
Bu çalışmanın amacı, termal çamur ve killerinden yararlanarak düşük derecede pişen fakat sır çatlağı olmayan seramik yapmaktır. Denizli Tekkeköy termal çam uru (gri kil) ve bölge kilinin (sarı kil) seramik bünyede kullanımı üzerine yapılan denemelerle, yeni sonuçlara ulaşarak seramik ve çini üretimine katkı sağlanması planlanmaktadır. Killer, yapısal özellikleri, yeryüzüne yakın bölgelerde oluşmaları sayesinde kolay erişilebilir olmaları, jeokimyasal olarak saflıkları ve atmosferik koşullara karşı yüksek oranda dayanım göstermeleri gibi özelliklerinden dolayı çok çeşitli alanlarda kullanılmışlardır. Ana malzemesi kil olan seramik de bu alanlardan biridir. Her geçen gün seramik alanında yeni gelişmeler olmaktadır. Seramik alanındaki gelişmeleri devam ettirmek için çeşitli malzemeler kullanılarak deneysel çalışmalar yapılmaktadır.
La interrupción voluntaria del embarazo como práctica médica en virtud de los derechos fundamentales al libre desarrollo de la personalidad y la salud de la mujer
Authors: Centeno Cardona Elkin , Mondragón Duarte Sergio Luis , Espinal-Arango Sara
Published: June 2023

Se estudia a la institución jurídica de la interrupción voluntaria del embarazo como una práctica médica segura, tal como ocurre con otros procedimientos clínicos y quirúrgicos, caso concreto el trasplante de órganos, la inserción de micro y nanochip en la persona humana, el cambio de sexo, por lo cual, apartando el debate sobre la moralidad pública cristiana, debe ser despenalizado a partir de lo consagrado en la Constitución Política de Colombia de 1991, en los artículos fundamentales como lo son el libre desarrollo de la personalidad, artículo 16 y el derecho fundamental a la salud integral, artículo 49, dado que si se despenaliza y se trata jurídica y clínicamente como un asunto de salud pública, no se vulnera la prohibición de tratos crueles, inhumanos y degradantes como se establece en el art. 12 superior.
An Introduction to Systematic Sensitivity Analysis via Gaussian Quadrature
Authors: Arndt Channing
Published: June 2023

Economists recognize that results from simulation models are dependent, sometimes highly dependent, on values employed for critical exogenous variables. To account for this, analysts sometimes conduct sensitivity analysis with respect to key exogenous variables. This paper presents a practical approach for conducting systematic sensitivity analysis, called Gaussian quadrature. The approach views key exogenous variables as random variables with associated distributions. It produces estimates of means and standard deviations of model results while requiring a limited number of solves of the model. Under mild conditions, all of which hold with respect to the GTAP model, there is strong reason to believe that the estimates of means and standard deviations will be quite accurate.
Long Run Simulations With GTAP: Illustrative Results from APEC Trade Liberalisation
Authors: Walmsley Terrie
Published: June 2023

In static applied general equilibrium models, the exogenous/endogenous split between variables (or closure) is used to infer the time frame over which the effects of a shock are simulated. This paper introduces a long-run closure for the GTAP model (Hertel and Tsigas, 1997) and uses this closure to simulate and compare the short-run and long-run effects of Asia-Pacific trade liberalisation. The approach explored here incorporates some relatively minor changes to existing GTAP theory in order to define a steady state in which growth rates of all real variables are uniform. Such uniformity must apply in the initial database (as well as in the post-shock solution). So to implement the new long run in GTAP a new initial database must first be created. Details concerning the creation of the new database are given, and results under the new approach are compared with those obtained under the old. The emphasis of this paper is on the development of a long-run closure in which the percentage change form equations of the model and the relationships between the levels variables in the GTAP database are consistent. Further research is required into these types of long-run closures to incorporate changes in ownership of capital to ensure that changes in welfare are adequately modelled. In the results reported here, GDP is not a useful guide to national welfare. The long-run closures introduced here are also compared with another comparative static long-run closure developed for GTAP by Francois, MacDonald and Nordström (1996). Technical Paper Number 9 can be downloaded in PDF format. To print this you will need the Adobe Acrobat Reader. For those interested in replicating the results in this technical paper, an associated zip file can be downloaded. The zip file includes a readme file with detailed instructions.
GTAP-E: An Energy-Environmental Version of the GTAP Model
Authors: Burniaux Jean-Marc , Truong Truong
Published: June 2023

Energy is an important commodity in many economic activities. Its usage affects the environment via CO2 emissions and the Greenhouse Effect. Modeling the energy-economy-environment-trade linkages is an important objective in applied economic policy analysis. Previously, however, the modeling of these linkages in GTAP has been incomplete. This is because energy substitution, a key factor in this chain of linkages, is absent from the standard model specification. This technical paper remedies this deficiency by incorporating energy substitution into the standard GTAP model. It begins by first reviewing some of the existing approaches to this problem in contemporary CGE models. It then suggests an approach for GTAP which incorporates some of these desirable features of energy substitution. The approach is implemented as an extended version of the GTAP model called GTAP-E, which includes the standard GTAP model as a special case. In addition, GTAP-E incorporates carbon emissions from the combustion of fossil fuels and this revised version of GTAP-E provides for a mechanism to trade these emissions internationally. The resulting behavior of agents in the model is analyzed using general equilibrium demand elasticities which summarize the combined effect of the new model specification. Implications for policy analysis are demonstrated via a simple simulation experiment in which global carbon emissions are reduced via a carbon tax. Results show that incorporating energy substitution into GTAP is essential for conducting analysis of this problem. The policy relevance of GTAP-E in the context of the existing debate about climate change is illustrated by some simulations of the implementation of the Kyoto Protocol. It is hoped that the proposed model will be used by individuals in the GTAP network who may not be themselves energy modelers, but who require a better representation of the energy-economy linkages than is currently offered in the standard GTAP model.
Caracterização de flora de restinga arbustivo-arbórea no sul de Santa Catarina, Brasil
Authors: Allison L. Tietz  , Romana Pedott Apel  , Denise M. D. S. Mouga
Published: June 2023

Na mata atlântica, estão agrupadas áreas semelhantes quanto à paisagem, com diferentes tipos vegetacionais, em conjuntos de ecossistemas associados. Dentre estes, há a restinga, caracterizada por solos arenosos, pobres em argila e matéria orgânica, com capacidade baixa de reter água e nutrientes e cuja cobertura estabiliza os sedimentos e mantém a drenagem natural. Visando obter dados sobre a comunidade florística em área de restinga arbustivo-arbórea, foi realizado um estudo na planície quaternária em Laguna (SC), na Trilha do Gravatá, de 16/6/2021 a 14/5/2022. Ao longo de um ano, uma vez por mês, durante seis horas (das 6 h às 12 h), através de caminhamento, procuraram-se plantas floridas na área, sendo estas fotografadas, coletadas, herborizadas e identificadas. Foram amostradas 37 espécies de plantas, de 20 famílias e 33 gêneros, com um maior número de espécies para a família Asteraceae (12 espécies), seguida por Myrtaceae (três espécies). Encontraram[1]se oito espécies endêmicas, 18 medicinais, 36 nativas, sete em diversas categorias de ameaça para conservação e seis formas de vida. Elaborou-se um calendário floral, que apresenta as espécies em fenofases. A relativa dificuldade de acesso à Trilha do Gravatá condiciona um uso de solo moderado, auxiliando na conservação da comunidade ali presente.
“In English my name means hope. In Spanish it means too many letters” Identity and Otherness in Sandra Cisneros’ Writings
Authors: Lemos Márcia
Published: June 2023

rn into a Mexican family, American writer Sandra Cisneros has repeatedly given voice to characters marginalized not only for being femalebut also for being Chicanas. Thoughapparently simple in their narrative modes, Cisneros’ texts present the readers with many complex layers of meaning in their endeavour to represent female expectations, anxieties and concerns in a world that is still very much challenging for women. One core concern is certainly language, reflecting the author’s divide between Spanish, her family’s mother tongue, and English, her own native language, and the language in which she writes. This paper will focus on two works by Cisneros: her 1984 novel The House on Mango Streetand her 2021 dual-language text Martita, I Remember You / Martita, te recuerdo: A Story in English and Spanish. The purpose of this paperisto address theimportance of linguistic choices in representing female identitiesandexperiencesof othernessin a largely patriarchal society. The title is inspired by a passage in The House on Mango Streetin which Esperanza, theyoung protagonist and narrator of the novel, reveals some discomfort about her ownname and specially the way it is constantly mispronounced by English speakers, including her teachers at school. Echoing Virginia Woolf, in Cisneros’ coming-of-age 1984 novel, female identity is dependent not only on getting a house of her own (away from the barrio),but also her own name,one that could be“la simple carte photographique d’identité”, as Proust would put it in À la Recherche du Temps Perdu(754)
Black Women’s Journey in America and the Need for Intersectionality A Comparative Reading of Maya Angelou’s “Still I Rise”, Lucille Clifton’s “won’t you celebrate with me” and June Jordan’s “Poem About My Rights”
Authors: Damas Ana Rafaela
Published: June 2023

Through a comparative reading of Maya Angelou’s “Still I Rise”, Lucille Clifton’s “won’t you celebrate with me” and June Jordan’s “Poem About My Rights”, this essay aims to analyse the black women’s journey in America, by consideringtheir identity and the adversitiesthey facedduring their path under the light of Kimberlé Crenshaw’s concept of “intersectionality”.
Perilaku Phubbing Dengan Kualitas Persahabatan Remaja Di Pekanbaru
Authors: Aiyuda Nurul , Heriandy Tebi , Putra Ardian Adi
Published: June 2023

Kualitas persahabatan merupakan sebuah ikatan hubungan yang terbentuk dan memiliki berbagai aspek dukungan, konflik, dan aspek kualitatif pertemanan yang dapat menentukan bagaimana sebuah hubungan persahabatan dapat berjalan dengan baik serta mampu menyelesaikan berbagai konflik yang dihadapi. Tinggi rendahnya kualitas persahabatan salah satunya dapat dipengaruhi oleh perilaku phubbing. Tujuan penelitian ini yaitu untuk mengidentifikasi hubungan antara perilaku phubbing dengan kualitas persahabatan di Pekanbaru. Penelitian ini menggunakan metode kuantitatif dengan analisis pearson product moment. Total sampel pada penelitian ini berjumlah 348 responden yang diambil menggunakan teknik quota sampling. Berdasarkan hasil penelitian yang dilakukan bahwa terdapat hubungan negatif antara perilaku phubbing dengan kualitas persahabatan remaja di Kota Pekanbaru dengan nilai signifikan sebesar 0,115 dan koefisien kolerasi -0,463, artinya semakin tinggi perilaku phubbing, maka semakin rendah kualitas persahabatan, sedangkan sebaliknya semakin rendah kualitas persahabatan. maka semakin tinggi perilaku phubbing pada remaja di Pekanbaru, Dengan demikian, perilaku phubbing yang dilakukan oleh remaja kota Pekanbaru memiliki hubungan dengan kualitas persahabatan.
Do animal à “intuição” “do sobrenatural”
Authors: Minhoto Marques João
Published: June 2023

Neste estudo procura-se compreender a relevância de diferentes representações da figura do ceifeiro em momentos também diferentes da modernidade literária portuguesa, nomeadamente as que ocorrem, respectivamente, em obras de Fialho de Almeida e de Francisco Bugalho. Este poeta, ao explicitamente convocar a leitura que Fialho faz daquela figura, procura distanciar a sua poética da proposta fialhiana. Deste modo, a referência a Fialho deve, por um lado, ser entendida no plano da recepção da sua obra no contexto da própria criação literária do século XX; por outro, importa ser compreendida no âmbito da poética bucólica, nomeadamente das configurações de que esta se reveste na época moderna e contemporânea. Neste contexto, a proposta de Fialho de Almeida de uma representação zoomórfica do homem desperta em Francisco Bugalho o que se pode equacionar como uma tentativa de conter as consequências da visão de uma nudez essencial. Sem poder esquecer-se o natural, enquanto processo de perda, procura-se ocupar o vazio com uma “intuição” “do sobrenatural”.
Articulações Entre o Museu do Festival do Cinema de Gramado, o Festival do Cinema e o Turismo Cultural Local
Authors: Barbacovi Manoela , Zubaran Maria Angélica
Published: June 2023

Este estudo se inscreve no campo teórico dos estudos culturais e elege como objeto de análise o Museu do Festival de Cinema de Gramado e suas articulações com o Festival do Cinema e o turismo cultural local. O objetivo central é refletir sobre o museu como um produtor cultural híbrido que, através da interatividade, aciona representações sobre o Festival do Cinema e acerca da própria cidade de Gramado, produzindo múltiplos significados entre os seus visitantes e dinamizando o turismo cultural local. Nesse sentido, algumas questões são centrais neste estudo: quais as estratégias representacionais acionadas na exposição permanente do Museu do Cinema de Gramado? Que representações culturais o museu comunica sobre o Festival de Cinema e a cidade de Gramado? Em termos metodológicos, utilizou-se a observação etnográfica da exposição permanente do museu com registros em um diário de campo. Dentre os achados contingentes e provisórios, destaca-se, sob a égide da convergência cultural pós-moderna, a modulação da cultura e da arte na exposição permanente do museu produzindo múltiplas articulações entre o Festival do Cinema, o museu e o turismo cultural na cidade de Gramado.
Plateia-Foyer: Diálogo e Formação de Público na Leitura Dramatizada em Artes Cênicas
Authors: Gushiken Yuji
Published: June 2023

O objeto deste artigo, em pesquisa de abordagem qualitativa, trajeto interdisciplinar e de natureza aplicada, é a formação de plateia de teatro, em sua eventualidade, e a busca pela sua transformação em público, virtualmente duradouro, através de práticas artísticas e comunicacionais designadas no campo das artes cênicas de “plateia-foyer” e “leitura dramatizada”. No plano teórico-metodológico, com objetivo descritivo e interpretativo, parte do modelo de estudos da comunicação como diálogo, característica do pensamento latinoamericano em comunicação, numa perspectiva de relações públicas, em que a prática da conversação e do comentário, entre a racionalidade da comunicação organizacional e o afeto da arte, emerge para a produção da vinculação social entre artistas e plateia/público. Opta-se por um estudo de caso sobre o Teatro Mosaico (Brasil), na montagem de dois textos dramatúrgicos: o Prólogo, do diretor Sandro Lucose (2005), e A Caravana da Ilusão, do diretor Alcione Araújo (2000), em que comédia e drama, no mesmo espetáculo, fazem bifurcar os caminhos de uma companhia teatral.
As Possibilidades Mediadoras da Arte: Um Estudo de Caso Sobre Experiência Artística e Participação Teatral de Pessoas com Deficiência Visual
Authors: Fontes Fernando , Carvalho Cláudia , Margarido Susete
Published: June 2023

Este artigo tem por base a experiência de implementação de um projeto de inclusão pela arte — A Meu Ver — por uma estrutura artística profissional da área do teatro da cidade de Coimbra: O Teatrão. Trata-se de um projeto de formação e prática teatral de pessoas cegas ou com baixa visão, com uma duração de três anos, financiado pela Fundação Calouste Gulbenkian e pela Fundação La Caixa, no âmbito do programa Partis & Art for Change. Este projeto agrega uma vertente de formação a uma vertente de intervenção no espaço cultural da cidade de Coimbra. O objetivo foi analisar e reequacionar os possíveis papéis da educação artística na mediação cultural, entendida como modelo de intervenção, entre a entidade O Teatrão e um grupo de pessoas com deficiência, tradicionalmente mais afastadas dos circuitos artísticos. A presente investigação privilegiou uma abordagem qualitativa, realizando um estudo de caso, de carácter exploratório, que decorreu entre outubro de 2021 e agosto de 2022. Os dados aqui reportados foram coletados através de quatro técnicas de recolha de dados: observação participante, inquérito por questionário, entrevistas semiestruturadas e grupo focal. Ao visibilizar a importância da experiência de criação artística na recomposição identitária das pessoas com deficiência, o projeto estimula a desconstrução de conceções da deficiência alicerçadas no modelo individual e fomenta uma conceção social da deficiência. O A Meu Ver, ao juntar pessoas com deficiência visual e profissionais do Teatrão, demonstra que os problemas das pessoas com deficiência não derivam das suas incapacidades, mas sim das formas de organização social e da cultura dominantes. Esta desconstrução permitiu-nos analisar os impactos individuais do projeto para os seus participantes diretos e evidenciar formatos de mediação cultural possíveis para o desenvolvimento de projetos com esta abordagem no setor cultural.