bluuebunny/crossref_metadata_2025 huggingface dataset:
Bevacizumab in recurrent WHO grades II–III glioma
Authors: Annakib Soufyan , Rigau Valérie , Darlix Amélie , Gozé Catherine , Duffau Hugues , Bauchet Luc , Jarlier Marta , Fabbro Michel
Published: July 2023

Purpose

The management of recurrent WHO grades II–III (rGII–III) glioma is not well established. This study describes the clinical outcomes in patients who received bevacizumab as rescue treatment.

Methods

In this retrospective study, the main inclusion criteria were as follows: adult patients with histologicaly proved rGII–III glioma according 2016 WHO classification treated with bevacizumab from 2011 to 2019, T1 contrast enhancement on MRI. Efficacy was assessed using the high-grade glioma 2017 Response Assessment in Neuro-Oncology criteria. Progression-free survival (PFS) and overall survival (OS) were estimated using the Kaplan–Meier method.

Results

Eighty-one patients were included (M/F ratio: 1.7, median age at diagnosis: 38 years) among whom 46 (56.8%) had an initial diagnosis of grade II glioma. Previous treatments included at least one surgical intervention, radiotherapy (98.8%), and ≥ 2 chemotherapy lines (64.2%). After bevacizumab initiation, partial response, stable disease, and progressive disease were observed in 27.2%, 22.2%, and 50.6% of patients. The median PFS and OS were 4.9 months (95% confidence interval [CI] 3.7–6.1) and 7.6 months (95% CI 5.5–9.9). Bevacizumab severe toxicity occurred in 12.3%. Twenty-four (29.6%) patients discontinued bevacizumab without radiological progression. Oligodendroglioma and age ≥ 38 years at diagnosis were more frequent in this subgroup (odds ratio = 0.24, 95% CI 0.07–0.84, p = 0.023 and 0.36, 95% CI 0.13–0.99, p = 0.042). Ten of these 24 patients were alive at 12 months and two patients at 8 years after bevacizumab initiation, without any subsequent treatment.

Conclusion

Bevacizumab can be an option for heavily pretreated patients with rGII–III glioma with contrast enhancement. In our study, bevacizumab displayed prolonged activity in a subgroup of patients.
Through a relational lens: reflections about foster care experience in Italian emancipated foster youth
Authors: Cardinali Paola , Bizzi Fabiola , Migliorini Laura
Published: July 2023

The study aimed to investigate relational outcomes of Italian emancipated foster youth across open-ended reflections about their perceptions of their relationships with the biological and foster family, with partner and peers. A total of 26 Italian emancipated foster youth (19–25 years old) recruited by social services completed a single in-depth interview. A qualitative thematic analysis was selected for this study. The results revealed two major themes of foster care experience that emerged often simultaneously from the participants’ narration: (1) Positive Relational Outcomes including “Feeling supported,” “Sense of belonging,” “Good memories,” “Relationship with family of choice,” and “Staying in touch”; and (2) Negative Relational Outcomes referring “Devaluation,” “Refuse,” “Bad memories,” and “Isolation.” Foster care experience leads to complex relational perceptions in emerging adulthood according to different relational outcomes and ways of processing foster care experience. Professionals could work on relational outcomes and memories, especially during a critical transition like emerging adulthood, to support youth in making sense of their past experiences.
Formative experiences and psychological distance in the lives of contemporary environmentalists
Authors: Raja Urooj S. , Carrico Amanda R.
Published: July 2023

Introduction

We use the term “environmentalists” to describe the people who are highly and actively engaged and involved in environmental issues like climate change. Environmentalists consistently advocate, research, or volunteer to do the work needed to address environmental challenges. Factors that drive contemporary environmentalists remain understudied.

Methods

We, therefore, ask: what formative experiences drive environmentalists on climate change and other environmental problems at present? We frame this exploration through the significant life experiences (SLE) literature, which examines people and environmental pathways. We also ask: how do feelings of perceptual/actual distance or closeness to environmental threats and climate change shape a person’s decision to become an environmentalist? We anchor this query to the psychological distance (PD) literature that explores how people perceive external phenomena and the role distance plays in their conception. To answer both questions, we use qualitative methods and draw on 33 interviews with environmentalists involved in environmental protection work for an average of 91 h in the past 4 weeks.

Results

We find that environmentalists spoke about several formative experiences broadly consistent with what has been documented in the SLE literature. Traumatic experiences were especially influential for our sample of environmentalists. Our findings also reveal that PD, especially social, plays a role in the lives of environmentalists.

Discussion

Study findings could help scholars and practitioners deepen their understanding of contemporary environmentalists. Practitioners, in particular, could use this knowledge to help environmentalists by providing them with tailored resources and support.
Safety climate perceived by pre-hospital emergency care personnel—an international cross-sectional study
Authors: Kosydar-Bochenek Justyna , Religa Dorota , Knap Małgorzata , Czop Marcin , Knap Bartosz , Mędrzycka-Dąbrowska Wioletta , Krupa Sabina
Published: July 2023

Introduction

Improving patient safety is one of the most critical components of modern healthcare. Emergency medical services (EMS) are, by nature, a challenging environment for ensuring patient safety. It is fast-paced, physically dangerous, and highly stressful, requiring rapid decision-making and action. This can create risks not only for patients but also for employees. We assessed variations in perceptions of safety culture in prehospital emergency care among an international sample of paramedics and nurses.

Methods

The Emergency Medical Services Safety Attitudes Questionnaire (EMS-SAQ) was used for the study. The instrument measures six domains of safety culture in the workplace: teamwork climate, job satisfaction, safety climate, working conditions, stress recognition, and perceptions of management. A total of 1,128 EMS from 9 countries participated in this study.

Results

Safety Climate was 81.32/100 (SD 6.90), Teamwork Climate 84.14/100 (SD 8.74), Perceptions of Management 76.30/100 (SD 10.54), Stress Recognition 89.86/100 (SD 5.70), Working Conditions 81.07/100 (SD 9.75), and Job Satisfaction 70.71/100 (SD 7.21). There was significant variation in safety culture scores across countries for teamwork climate (TWC), working conditions (WC), and job satisfaction (JS). Among the individual variables (age, gender, level of education, and work experience), variations in safety culture scores were unaffected by age, gender, or work experience. Organizational characteristics: employment status and position type were linked to significant variations in safety culture domain scores.

Conclusion

Participants’ perceptions of the patient safety climate were not particularly satisfactory, confirming that there is still a need to develop a culture of patient safety in prehospital emergency care.
Sparse Signal Recovery through Long Short-Term Memory Networks for Compressive Sensing-Based Speech Enhancement
Authors: Shukla Vasundhara , Swami Preety D.
Published: July 2023

This paper presents a novel speech enhancement approach based on compressive sensing (CS) which uses long short-term memory (LSTM) networks for the simultaneous recovery and enhancement of the compressed speech signals. The advantage of this algorithm is that it does not require an iterative process to recover the compressed signals, which makes the recovery process fast and straight forward. Furthermore, the proposed approach does not require prior knowledge of signal and noise statistical properties for sensing matrix optimization because the used LSTM can directly extract and learn the required information from the training data. The proposed technique is evaluated against white, babble, and f-16 noises. To validate the effectiveness of the proposed approach, perceptual evaluation of speech quality (PESQ), short-time objective intelligibility (STOI), and signal-to-distortion ratio (SDR) were compared to other variants of OMP-based CS algorithms The experimental outcomes show that the proposed approach achieves the maximum improvements of 50.06%, 43.65%, and 374.16% for PESQ, STOI, and SDR respectively, over the different variants of OMP-based CS algorithms.
Long-Term Results of Prevention of Complications After Medical Abortion
Authors:   Dagestan State Medical University, Esedova A.E. , Islamova A.Yu. , Magomedova T.S. , Mamedov F.S.
Published: July 2023

Relevance. The frequency of abortion complications ranges from 2.0 to 52.0%. The effectiveness of the magneto-IR light laser and ozone, which have immunomodulatory, bactericidal, analgesic effects. Purpose to increase the effectiveness of measures to reduce the number of complications after medical abortion. Material and methods. 124 patients after abortion were examined and divided into 3 groups. In the main group I 52 (42.0%) women who were treated with antibiotics with magneto-IR light laser and ozone. In the main group II, 24 (19.3%) patients were treated with magneto-IR light-laser and ozone therapy, without antibiotics. The control subgroup consisted of 48 (38.7%) patients without prophylaxis. Results. The patients were examined 3, 6 and 12 months after the abortion. In the main group I, menstrual function was restored after 3 months in 36 (69.2%) patients, in the main group II 16 (66.7%) and control 26 (54.1%), more than 8 days continued in 16 (30.8%), 8 (33.7%) and 22 (45.9%) accordingly. After 6 months and a year, menstruation remained impaired in 2 (3.9%) patients of the main group I, in 1 (4.1%) of the main group II and in 6 (12.5%) of the control group. In the main group I, 27 (52.0%) women planned pregnancy. Pregnancy occurred in 10 (19.2%) patients: 7 (13.4%) ended in childbirth, 2 (3.9%) miscarriage, 1 abortion. In the main group II, 12 (50.0%) women planned pregnancy. Pregnancy occurred in 5 (20.9%): 4 (16.7%) they ended in childbirth and 1 (4.1%) miscarriage. In the control group, 25 (52.0%) patients planned pregnancy. It occurred in 7 (14.5%) patients: 3 (6.2%) ended in childbirth and 4 (8.3%) miscarriage. Conclusions. Magneto-IR light-laser and ozone therapy is an effective way of prevention, promotes faster recovery of menstrual and reproductive function
Giant Juvenile Fibroadenoma of the Breast in a 13-Year-Old Girl: a Case Report. Diagnostic Features
Authors:   Russian Children’s Clinical Hospital of N.I. Pirogov Russian National Research Medical University, Sibirskaya Ye.V. , Karachentsova I.V. , Melenchuk I.A. ,   N.I. Pirogov Russian National Research Medical University,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Gripas D.Yu. , Ukolova S.K.
Published: July 2023

The article describes a clinical case of giant fibroadenoma in a 13-year-old girl, whose size was 20 cm, as well as a brief review of the scientific literature on benign neoplasms of the mammary glands in young patients. Giant fibroadenomas account for 0.5 to 2% of all fibroadenomas. In children and adolescents, ultrasound of the mammary glands is the main method of diagnosing fibroadenoma. Fibroadenoma needs to be differentiated from a phylloid tumor, which is clinically no different from fibroadenoma, but at the same time it has a high risk of malignancy. To make a final diagnosis, a puncture fine needle aspiration biopsy is additionally perform
Quality of Life in Patients with Inflammatory Bowel Diseases and Irritable Bowel Syndrome: What Is Common?
Authors:   Novosibirsk State Medical University, Kulygina Y.A. , Osipenko M.F.
Published: July 2023

Inflammatory bowel diseases (IBD) and irritable bowel syndrome (IBS) are chronic bowel diseases affecting young people, leading to a decrease in working capacity and having a negative impact on the quality of life (QOL). The syndrome of excessive bacterial growth in the small intestine (SIBO) is often combined with organic and functional intestinal diseases, worsening the clinical picture and worsening the quality of life of patients. Recently, there has been an increase in the number of diagnosed cases of bacterial overgrowth syndrome in the small intestine, which is primarily due to the availability of hydrogen breathing tests (VDT), which facilitate the diagnostic process. Objective. QOL analysis of patients with IBD and IBS, depending on the presence or absence of SIBO. Material and methods. The study included 152 patients with IBD and 100 patients with IBS. All patients underwent VDT for the verification of Iron the "Gastro+" device using lactulose. To access QOL a general questionnaire for both groups of patients (SF-36) and were used specialized questionnaires IBD (IBD) and IBS-QOL (IBS). Results. The presence of SIBО in both IBD and IBS patients is associated with a decrease in quality of life indicators reflecting both physical and mental health. Corresponding changes on all scales were detected when using specific questionnaires (IBDQ and IBS-QOL) and on the part of most scales when using the SF-36 questionnaire, except for the "vitality" scale, the "social functioning" scale – in patients with IBD and the "general health" scale – in patients with IBS.
APPLICATION OF MARKETING LOGISTICS IN RETAIL
Authors:   Chernivtsi Institute Trade and Economics of SUTE, Chernivtsi, Olena Bozulenko , Yurii Chaplinskyі ,   Chernivtsi Institute Trade and Economics of SUTE, Chernivtsi
Published: July 2023

Retail is the most competitive industry in entrepreneurship, with many companies offering similar goods and services. Marketing logistics is one of the key factors that help companies stand out from their competitors and increase their profits. Marketing logistics ensures the delivery of goods and services in the right time, place, and quantity, which allows for maximum customer satisfaction and increased loyalty. At the same time, marketing logistics reduces costs for storage, transportation, and delivery of goods. However, in practice, many retail companies do not use marketing logistics properly, leading to low business efficiency and decreased competitiveness. Therefore, the problem of effective use of marketing logistics in retail is relevant. The goal of the research is to apply marketing logistics in retail and identify the problems that hinder its effective use. In the research process, general scientific methods such as analysis, systematization, and generalization were used. Marketing logistics is an important element in the effective management of retail goods supply. The use of marketing logistics in retail allows a reduction in the costs of goods supply, an increase in business profitability, as well as the attraction of new customers and increased loyalty from existing ones. Marketing logistics helps in supply chain management, ensures accurate delivery of goods, and improves customer service quality, which is reflected in increased business profits. The use of the approaches mentioned in the article by retail companies will allow optimal support of sales of goods and services. The main practical advantages of using marketing logistics in retail include: cost reduction for logistics, improved service quality, improved product quality standards, increased sales, improved inventory management efficiency, and increased competitiveness. The analysis of the world experience of using marketing logistics in retail allows identifying the most effective approaches and strategies for its implementation, which can be used by companies to improve their business efficiency and increase their competitiveness.
PERBANDINGAN KELUHAN MUSKULOSKELETAL PADA MAHASISWA FAKULTAS KEDOKTERAN DENGAN DAN TANPA GANGGUAN SOSIAL MEDIA
Authors: M Idrus Baagil Fatma , Bustamam Nurfitri , Safira Lisa
Published: July 2023

Pada pandemi COVID-19 sebagian besar aktivitas mahasiswa kedokteran dilaksanakan secara daring. Hal tersebut membuat mahasiswa berisiko mengalami gangguan sosial media dan keluhan muskuloskeletal. Penelitian ini bertujuan untuk mengetahui bagaimana perbandingan keluhan muskuloskeletal antara mahasiswa kedokteran dengan atau tanpa gangguan sosial media. Penelitian menggunakan desain potong lintang dan teknik stratified proportional random sampling pada mahasiswa kedokteran Universitas Pembangunan Nasional “Veteran” Jakarta tahun 2021. Instrumen penelitian yang digunakan adalah kuesioner karakteristik subjek, Nordic Body Map dan Social Media Disorder questionnaire. Hasil analisis didapatkan 32,8% dari 64 subjek mengalami gangguan sosial media. Bagian tubuh yang banyak mengalami keluhan adalah leher (47,6%), tengkuk (42,9%), punggung (52,4%), pinggang (61,9%), dan pergelangan tangan kanan (7%). Hasil uji Chi-square exact didapatkan perbedaan keluhan muskuloskeletal antara mahasiswa yang mengalami gangguan sosial media dan yang tidak mengalami gangguan sosial media (p = 0,001). Terdapat perbedaan keluhan pada leher dan pinggang antara mahasiswa yang mengalami gangguan sosial media dengan yang tidak mengalami gangguan sosial media (p < 0,05). Hasil penelitian ini menunjukkan perlunya self awareness terhadap keluhan fisik muskuloskeletal dan gangguan sosial media sehingga masalah tersebut dapat segera diatasi.

During the COVID-19 pandemic, most medical student activities were held online. These put students at risk for social media disorders and musculoskeletal complaints. This study aims to compare musculoskeletal complaints between medical students with or without social media disorders. The study used a cross-sectional design with a stratified proportional random sampling technique towards medical students of Universitas Pembangunan Nasional “Veteran” Jakarta in 2021. The research instruments used were the subject characteristics questionnaire, the Nordic Body Map, and the Social Media Disorder questionnaire. The results of the analysis showed that 32.8% of 64 subjects experienced social media disorders. The body parts that experienced the most complaints were the neck (47.6%), the nape (42.9%), the back (52.4%), the waist (61.9%), and the right wrist (7%). The results of the Chi-square exact test showed differences in musculoskeletal complaints between students who experienced social media disorders and those who did not experience social media disorders (p = 0.001). There are differences in complaints about the neck and waist between students who experience social media disorders and those who do not experience social media disorders (p<0.05). The results of this study indicate the need for self-awareness of musculoskeletal physical complaints and social media disorders so that these problems can be treated immediately.
BAĞLAMADA TEL AYIRMA TEKNİĞİ
Authors: ÇANAKÇI ERKAN , MAK MAHİR
Published: July 2023

In this study, firstly, the journey of kopuz, which is accepted as the ancestor of the baglama family towards today's geography is mentioned. In addition to the change experienced by the kopuz, which has emerged in a rich range as baglama family in Anatolia, innovative initiatives applied in the baglama family are also included. Thus, we have tried to underline which baglama we should talk about. Then, the written methods on baglama and instruments with 6 and 7 strings, which are now described as "baglama" (short and long necked) and played in baglama and disordered tuning, were examined. The baglama, which was accepted to be played by hand (tapping or playing without a plectrum), began to be played with a plectrum over time, far ahead of its performance with tapping. The baglama performances with tapping, which were recalled after 1980s, have become much more developed and widespread today. The string separation technique, which has been taken into consideration since 2003, actually brought together the traditional performance form of tapping and plectrum technique. Erkan Çanakçı tried to find an answer to the need for harmony in folk music with traditional playing methods by blending these two techniques without disturbing the traditional structure of baglama. During the maturation process of the article, resources related to the field of study were accessed with the document analysis method, it has been applied to different age groups who have learned the strings separation technique since 2003, concerts and recordings have been made in various platforms and performance areas. In addition, a special transcription showing this technique was prepared and presented in the article. Keywords: Baglama, Baglama Methods, Selpe, Strings Separation Technique, Kopuz.
SIRRI ZAMANA SIĞDIRMAK MÜMKÜN MÜ?: MESNEVÎ’YE YANSIYAN YÖNÜ İLE MEVLÂNA’NIN ZAMAN ANLAYIŞI
Authors: GÜRER BETÜL
Published: July 2023

Time is one of the most essential truths that is at the centre of human life and that human beings contact with. It has always been the subject of the thought both because various dimensions it includes, because it is perceived differently in different situations, and with its ambivalence that prompt people to think about it intensely. For this reason, a wide range of literature has emerged over time. In sūfī sources, time is generally mentioned within the framework of the term ibn al-waqt (the son of time). In this study, Mawlānā Jalāl al-Dīn al-Rūmī’s understanding of time was discussed in focus of his book Mathnawī. The couplets in Mawlānā’s Mathnawī related wit time have been determined and his teaching has been compared with the classical sources of sufism and the time view of Muhyiddin Ibn ʿArabī, one of the founders of sūfī thought. Mawlānā handles time in the framework of three main categories. The first of these is the transcendental understanding of time, which is not subject to division such as past and future, the second is horizontal/ linear/chronological time, and the third is the timeless dimension experienced by ibn al-waqt reaching the position of abu'l-waqt (father of time) by evolving and getting rid of the time. Mawlānā also mentions on the extent to which divine secrets and metaphysical truths can be expressed in the context of chronological time. According to him, it is impossible for such information to be fully expressed in horizontal time, that is, “the secret cannot be forced into time”. The determination of Mawlānā’s views on time has great importance in terms of revealing the time approach of mystical thought and tradition. Keywords: Sūfism, Mawlānā Jalāl al-Dīn al-Rūmī, Mathnawī, Ibn al-waqt/The son of time.
TÜRK SİNEMASINDA “HACI BEKTAŞ VELİ” TEMSİLLERİ
Authors: KOLUAÇIK İHSAN , CANTAŞ AZİME
Published: July 2023

Hacı Bektaş Veli is one of the most important names of Turkish Islam. Various sources and groups paint different and completely opposite Hacı Bektaş portraits. While some describe Hacı Bektaş as a Sunni mystic, others consider him a representative of heterodox Islam. In addition, there are those who turn Hacı Bektaş into a purely political figure and show him as a symbol of resistance that stands by the working people against injustices. It is possible to come across cultural references and representations of this belief in cinema as a mass art. In this direction, the study aims to reveal the reflections of Hacı Bektaş representations, which have a great importance in the beliefs and values of Turkish society, but have discussions between his real and hisopic personality, on the cinema. Through the descriptive analysis and discourse analysis included in the qualitative research methodology, how a tradition reflected in Turkish cinema is defined and how it is interpreted has been evaluated through sample films. In the applied descriptive analysis, instead of interviews, the thematic framework in the films was set up and how it was evaluated, while it was tried to reveal how filmmakers and directors with different ideas reflect these values in the social structure they are in and their views on Hacı Bektaş Veli. Only one Hacı Bektaş Veli movie has been shot since its inception. This film is Hacı Bektaş’ı Veli (Those who Turkified Anatolia), which was shot by T. Fikret Uçar in 1967 and tried to convey sections from the lives of religious figures called “hazli films” within the aesthetics of Yeşilçam. In addition to the movie Hacı Bektaş Veli, the characters of Hacı Bektaş Veli are also encountered in the movies where Yunus Emre's life story is told. In the study, it has been determined that the representations of Hacı Bektaş examined in Turkish cinema vary in relation to the ideological thoughts and beliefs of the directors or screenwriters. Keywords: Cinema, Turkish Cinema, Hacı Bektaş Veli, Yunus Emre, Descriptive Analysis.
NESİMİ’NİN LİRİKASI: İRFANÎ MÜNDERİCE VE POETİK ZİNETLER
Authors: KULİYEVA MAHİRE
Published: July 2023

The article presents a monograph by Saadet Shikhiyeva. Her monograph "Nesimi's Lyrics: Wisdoom Content and Poetic Decorations" discusses the themes of Nasimi's creativity that have not been studied so far and the place of the poet in the history of Azerbaijani philosophical poetry. In this work, research on Nesimi was carried out on two divans of the poet, which he wrote in Azerbaijani Turkish and Persian. Keywords: Nesimi, Shikhiyeva, Hurufism.
SÜHREVERDİ, RİSÂLETÜ’L-FÜTÜVVE
Authors: DOĞAN TURAY ESRA
Published: July 2023

This study consists of the translation of Risaletü'l-futüvve by Abu Hafs Şihâbüddin Ömer b. Muhammed b. Abdillâh b. Ammûye el-Kureşî el-Bekrî es-Sühreverdî (d. 632/1234), who has an important place in the history of Fütüvvet. Sühreverdi took part in the institutionalization of Fütüvvet during the Abbasid State and undertook the management of the first formation. Risâletü'l-fütüvve, which is among the sources of Fütüvvet and has an important place, is located between leaves 154a-158b in a mecmua located in the Süleymaniye Library, Ayasofya 2049. Keywords: Suhrawardi, Risalatu’l-Futuwwa, Futuwwatnama.
Triage and the Art of Institutional Research
Authors: Norris Donald
Published: July 2023

There is an overwhelming tide in the affairs of humankind toward increasing complexity and information overload. Simple ideas are rendered complex, and complex ideas become obscured by too much information, jargon, and professional mumbo jumbo. This tide has become a tidal wave in the academic world. Institutional researchers are often preoccupied with the more complex and arcane aspects of research design, ever-growing management of information systems, and the configuration of sophisticated "decision-support systems." Yet, the finest work of analysis imaginable can be rendered ineffective if it is not presented thoughtfully and in a manner congruent with the needs and preferences of decision makers. Indeed, the single most precious gift that an analyst can give is the clear and thoughtful presentation of the bare minimum of information necessary for the task. This is what separates successful institutional researchers from those who toil in the vineyards with little achievement or recognition.
Decision Support Systems for Academic Administration
Authors: Moore Laurence , Greenwood Allen
Published: July 2023

Decision Support Systems arrived in academic administration in the 1980s with a great deal of enthusiasm and controversy. What are they? What can they do for you? This issue introduces the reader to Decision Support Systems (DSS) and discusses how DSS might help academic administrators make decisions. It includes (1) a description or definition of DSS, (2) a brief historical development sketch, (3) an illustration of an application of DSS in academic administration, and (4) references on the subject of DSS.
FACTORS INFLUENCE CUSTOMER AWARENESS OF HALAL COSMETIC PRODUCTS
Authors: Fuad Nurwahida , Bohari Abdul Manaf , Kassim Shamshul Anaz , Ahmad Zulaiha
Published: July 2023

The halal beauty industry is currently expanding. The levels of consumer awareness regarding the components used in skincare and cosmetics products have significantly increased. In Malaysia, halal cosmetic products are rapidly gaining popularity among consumers and business stakeholders despite the abundance of other commercial goods available today. The demand and supply in the local cosmetic sector are being significantly reshaped by the growing degree of education and knowledge regarding halal products. Unfortunately, there has not been much research done on halal cosmetics. Therefore, the purpose of this study was to find out the effect of advertising, knowledge, attitude, product characteristics and social influence that may assist in customer awareness of halal cosmetic products. The total of 384 customers in Perlis participated in this study voluntarily. The data collection based on self-administered questionnaire. The time horizon of the study conducted was one year. The data was analysed using descriptive and regression analysis. The findings obtained in this study indicated that advertising, knowledge, attitude, product characteristics and social influence had significant positive relationship with customer awareness. This results provide valuable insight for the body of knowledge in the field of halal research as well as the development of the halal products industry.
Pengaruh Copywriting Promotion, Online Customer Review, dan Gaya Hidup Terhadap Keputusan Pembelian Melalui Keranjang Kuning Pada Aplikasi Tiktok
Authors: Ruqoyyah Umi , Rahmawan Ginanjar
Published: July 2023

Penelitian ini bertujuan untuk mengetahui pengaruh copywriting promotion, online customer review, dan gaya hidup terhadap keputusan pembelian melalui keranjang kuning pada aplikasi Tiktok serta untuk mengetahui pengaruh copywriting promotion, online customer review, dan gaya hidup secara bersama-sama terhadap keputusan pembelian melalui keranjang kuning pada aplikasi Tiktok. Metode yang digunakan adalah metode kuantitatif dengan teknik analisis data uji instrument data, uji asumsi klasik, dan analisis regresi linier berganda menggunakan aplikasi SPSS. Penulis menggunakan non-probability sampling untuk pengambilan sampel dengan teknik purposive sampling. Didapatkan sampel sebanyak 166 responden yang pernah belanja melalui keranjang kuning pada aplikasi Tiktok di Solo Raya. Hasil dari penelitian ini adalah variabel copywriting promotion, online customer review, dan gaya hidup berpengaruh signifikan secara parsial terhadap keputusan pembelian melalui keranjang kuning pada aplikasi Tiktok. Variabel copywriting promotion, online customer review, dan gaya hidup secara simultan berpengaruh signifikan terhadap keputusan pembelian melalui keranjang kuning pada aplikasi Tiktok.
ANALISA PENGARUH ANALISA JABATAN DAN ANALISA BEBAN KERJA TERHADAP KINERJA SUMBER DAYA MANUSIA PADA DINAS PEKERJAAN UMUM DAN PENATAAN RUANG PROVINSI SUMATERA UTARA
Authors: Pardosi Ananda , Andronicus Melkyory , Tumanggor Andi Bagus Rizky , Manurung Eva Rusvalina , Salunia Salunia , Sri Rahayu Sri Rahayu
Published: July 2023

Penelitian ini bertujuan untuk meneliti mencari tahu lebih dalam mengenai Dinas Pekerjaan Umum dan Penataan Ruang Provinsi Sumatera Utara adalah sebuah organisasi pemerintahan yang bergerak menyelenggarakan perumusan dan pelaksanaan di bidang penyelenggaraan jalan sesuai dengan ketentuan perundang-undangan di bawah naungan Dinas Pekerjaan Umum (PU). Untuk mendapatkan sumber daya manusia yang paling tepat dan sesuai dengan kebutuhan organisasi agar mendapatkan kinerja yang maksimal dari sumber daya manusia tersebut, maka Dinas Pekerjaan Umum dan Penataan Ruang Provinsi Sumatera Utara menggunakan analisa jabatan dan analisa beban kerja. Dalam melakukan analisa jabatan, Dinas Pekerjaan Umum dan Penataan Ruang Provinsi Sumatera Utara menetapkan deskripsi kerja yang sesuai dengan jabatan yang akan diduduki dan spesifikasi kerja. Sementara pada analisa  beban kerja yang dijalankan Dinas  Pekerjaan Umum dan Penataan Ruang  Provinsi Sumatera Utara ditetapkan bahwa beban kerja yang harus dipenuhi dalam satu bulan adalah 6000 menit jam kerja atau 22 hari kerja dalam sebulan. Tetapi yang terjadi, masih ada sumber daya manusia yang tidak memenuhi beban kerja tersebut, dimana yang paling signifikan terjadi pada bulan April dan Juni 2022 yaitu terdapat 38 dan 30 orang yang tidak memenuhi beban kerja. Maka perlu dilakukan analisa jabatan dan analisa beban kerja dengan melakukan pengujian-pengujian salah satunya Uji Koefisien Determinan menggunakan Spss maka diketahui nilai dari Abjusted R Square (Koefisien Determinan) sebesar 0,063 yang artinya pengaruh variabel independen (X) terhadap variabel dependen sebesar 6,3%.
PENGARUH KOMPETENSI KERJA, DISIPLIN KERJA DAN FLEKSIBILITAS KERJA TERHADAP KINERJA KARYAWAN DI ERA NEW NORMAL PADA PT. TORGANDA KANDIR MEDAN
Authors: Subakti Ripaldo , Rajagukguk Sri Meilin , Hutahaean Van Daniel , Nazmi Hendra , Fahmi Nur Augus
Published: July 2023

Tujuan penelitian ini ialah untuk mengetahui Pengaruh Kompetensi Kerja, Disiplin Kerja Dan Fleksibilitas Kerja Terhadap Kinerja Karyawan Di Era New Normal Pada Pt. Torganda Kandir Medan. Penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian eksplanatori. Direncanakan, penelitian ini akan dilaksanakan selama 3 bulan mulai dari November 2022 hingga Januari 2023 di PT. Torganda Kandir Medan, yang berlokasi di JL. Abdullah Lubis No.26, Babura, Kec. Medan Baru, Kota Medan, Sumatera Utara 20153. Populasi dalam penelitian ini adalah seluruh karyawan PT. Torganda Kandir Medan, dengan sampel yang diambil adalah seluruh karyawan tetap PT. Torganda Kandir Medan. Pengumpulan data dilakukan melalui penggunaan kuesioner yang akan didistribusikan kepada karyawan sebagai responden. Selain itu, wawancara juga dilakukan dengan karyawan PT. Torganda Kandir Medan. Metode ini

Digunakan peneliti untuk mendapatkan informasi tentang perusahaan berdasarkan laporan yang diberikan oleh perusahaan. Data primer dalam penelitian ini mencakup hasil wawancara dengan karyawan PT. Torganda Kandir Medan dan pengisian kuesioner yang diberikan kepada perusahaan tersebut. Sementara itu, sumber data sekunder melibatkan studi dokumentasi. Berdasarkan hasil penelitian dan pembahasan, secara parsial variabel Kompetensi Kerja memiliki pengaruh positif dan signifikan terhadap kinerja karyawan PT. Torganda Kandir Medan di era New Normal. Begitu pula, secara parsial variabel Disiplin Kerja juga memiliki pengaruh positif dan signifikan terhadap kinerja karyawan PT. Torganda Kandir Medan di era New Normal. Selain itu, secara parsial variabel Fleksibilitas Kerja juga memiliki pengaruh positif dan signifikan terhadap kinerja karyawan PT. Torganda Kandir Medan di era New Normal.
PENGARUH KUALITAS PRODUK, HARGA DAN PROMOSI TERHADAP LOYALITAS KONSUMEN SHOPEE (STUDI KASUS PADA MAHASISWA FAKULTAS HUKUM UNIVERSITAS PRIMA INDONESIA)
Authors: Bangun Tedi Sumarna , Purba Mas Intan , Ginting Riski Epreden , Br Keliat Fitrija Yolina , Wardani Nurul
Published: July 2023

Tujuan penelitian ini adalah untuk menguji pengaruh kualitas produk, harga, dan promosi terhadap loyalitas konsumen pengguna Shopee di Fakultas Hukum Universitas Prima Indonesia. Pengumpulan data diperoleh dengan menyebarkan kuesioner menggunakan skala Likert, teknik analisis regresi linear berganda dipilih dengan benar untuk digunakan sebagai dasar pengujian hipotesis dalam penelitian ini. Hal ini dikarenakan pada prinsipnya regresi linear berganda digunakan untuk mengetahui hubungan antara variabel bebas dan tidak bebas, seberapa besar variabel tidak bebas mempengaruhi variabel independen sehingga pada akhirnya dapat ditentukan juga apakah ada hubungan positif dan signifikan antara variabel yang diteliti. Hasil penelitian menyimpulkan bahwa terdapat hubungan positif dan signifikan antara variabel Kualitas Produk terhadap Loyalitas Konsumen Shopee (Studi Kasus pada Mahasiswa Fakultas Hukum Universitas Prima Indonesia), Terdapat hubungan positif dan signifikan antara variabel Harga terhadap Loyalitas Konsumen Shopee (Studi Kasus pada Mahasiswa Fakultas Hukum Universitas Prima Indonesia), Terdapat hubungan positif dan signifikan antara variabel-variabel Promosi yang berpengaruh positif dan signifikan terhadap Loyalitas Konsumen Shopee (Studi Kasus pada Mahasiswa Fakultas Hukum Universitas Prima Indonesia), yaitu variabel independen Kualitas Produk,Harga, dan Promosi mempengaruhi variabel non-bebas Loyalitas Konsumen sebesar 52,9% sedangkan sisanya 47,1% (100% - 52,9%) dijelaskan oleh variabel lain yang tidak diteliti dalampenelitian ini, seperti kepuasan konsumen, layanan admin toko kepada konsumen dan sebagainya.
Evaluation of Pharmaceutical Services and Drug Use (PKPO) in Hospital Pharmacy Installation
Authors: Susiyarti Susiyarti , Pamudji Gunawan , Iswandi Iswandi
Published: July 2023

Good and professional service is a hope for all levels of society, especially health services in hospitals, especially pharmaceutical services and drug use. The research was conducted at the Pharmacy Installation of the Mutiara Bunda General Hospital of Brebes. The purpose of this study was to determine the level of conformity of the seven PKPO standards to SNARS Edition 1 and their improvement strategies based on the priority of the percentage of achievement of accreditation and hospital needs. This research was a non-experimental research design, data collection using PKPO survey instruments with interview and observation methods. The research subjects were pharmacists and other pharmacy installation staff. The data result were processed in tabular form, the level of conformity of each PKPO standard was compared to SNARS Edition 1 of 2018 with a minimum standard of 80%. The results of the PKPO level of conformity at the Pharmacy Installation of RSU Islami Mutiara Bunda was not fully in accordance with SNARS. The percentages were obtained PKPO 1 of 100%, PKPO 2 of 8,00%, PKPO 3 of 69,04%, PKPO 4 of 84,61%, PKPO 5 of 80,0%, PKPO 6 of 100% and PKPO 7 of 87,50 %. Based on the percentage of achievement and the level of need for IFRS, the priority order of improvement strategies that need to be immediately carried out by hospitals are PKPO 3 standards, namely storage, PKPO 2 standards regarding selection and procurement, then PKPO 7, PKPO 4 and PKPO 5.
Differences in Heart Rate and Oxygen Saturation of Babies Who Have Initiated Early Breastfeeding and Not Initiated Early Breastfeeding
Authors: Utami Ulfa Nadiya Putri , Ahmad Mardiana , Alasiry Ema , Yuliana Syam  , Usman Andi Nilawati , Ramadhani Sri
Published: July 2023

Early Initiation of Breastfeeding (IMD) is one of the efforts in the delivery room that has proven to have many benefits, but its implementation is still in accordance with the existing Standard Procedures so that the expected results are not appropriate and the provision of IMD is still low. The population of this study were all babies born with normal baby weight. The sample in the study amounted to 510 infants consisting of 255 infants with the IMD group for 1 hour according to the SOP and 255 groups that did not do IMD. This research is an observational study with a prospective cohort approach. sampling technique used purposive sampling. Data using a questionnaire instrument and data analysis using Chi-Square test, Fisher Exact test and General Linear Model + Post Hoc. The study found the baby's heart rate at 15 minutes (p-value =0,028) and 30 (p-value=0,002) (p-value<0,05) and 45 minutes (p-value=0,062) and 60 minutes (p-value=0,688) (p-value>0,05) using the Chi-Square test, Fisher Exact test. While the oxygen saturation of newborns at 15, 30, 45 and 60 minutes was 0,000 (p-value<0,05) using the General Linear Model+Post Hoc test. There was a difference in the baby's heart rate between the groups who did IMD and those who didn't do IMD at the 15th and 30th minutes.
PENGARUH PERBEDAAN SUHU PEREBUSAN DAN KONSENTRAS NaOH TERHADAP KUALITAS BUBUK TULANG IKAN GABUS (Channa striata)
Authors: Cucikodana Yunita , Supriadi Agus , Purwanto Budi
Published: July 2023

The purpose of this Â research was to observe the quality of snake head fish bone powder using different boiling Â temperature and NaOH concentration.The Factorial Randomized Block Design was used with two factors of treatment and 2 replications. The different boiling temperatures (60 0C, 650C, 700C) and three different NaOH concentrations (Control 0%, NaOH 2%, NaOH 4% and NaOH 6%). The parameters were yield, whiteness, density, Â solubilityÂ  and calcium content. The result showed that the treatments significantly effected the yield (43.98%-97.47%), whiteness (47.6-58.48%) density (0.51â€“0.67 g/ml), solubility(11.38-23.76%) and calcium content (16.86-22.77%). Â  Keyword :bone powder, snake head, calcium
Analisis Mutu Ikan Lele (Clarias batrachus) Asap Produksi Rakyat di Jalan Lintas Musi II Desa Keramasan, Kertapati, Palembang
Authors: Citra Firnanda , Yuliati Kiki , Baehaki Ace
Published: July 2023

The purpose of this research was to analize the quality of smoked catfish sold at Musi Dua street data were obtained through and series of survey. The smoke fish processing staser were material of supply, clear of weeds, washing of fish, work with salt and furnigation. Furnigation was a process in very important because can be specific character of smoke fish in the production. The result of the microbiology smoke catfish with sampling showed average be able to 1.8x106, 1.7x106 and 1.65x107. The result of the chemistry analysis smoke catfish showed in water activity of testing was about 0.84. The result standard water of testing showed smoke catfish was about 46.8% until 48.8% for every sample.
Madu sebagai Wet Batter pada Produk Udang Breaded
Authors: Gustina Nadia , Yuliati Kiki , Lestari Shanti Dwita
Published: July 2023

The purpose of this research is to determine the effect honey as a wet batter on the breaded shrimp quality. The research was conducted from February 2014 until September 2014. The results showed that were analyzed using randomized complete block design (RCBD). Parameters observed were chemical analysis (moisture content), pH measurement, water activity (aw), analysis of microbiological (TPC) and sensory analysis. Chemical characteristics of breaded shrimp in this study with the average of water content between 67.27% - 80.25%, pH value was 6.45 â€“ 7.98, the average value of water activity (aw) was 0.73 â€“ 0.97. While the values of the sensory analysis was 3.6 â€“ 8.6.
The Influence of the Work Environment, Organizational Commitment, and Information Technology on Employee Performance at KSP CU Dharma Prima Kita Yogyakarta
Authors: Andi Andi , Kurniawan Ignatius Soni
Published: July 2023

This study aims to determine the effect of the work environment, organizational commitment, and information technology on employee performance. The population used in this study were employees of KSP CU Dharma Prima  Kita, Yogyakarta. This research is a quantitative study and primary data was taken using a questionnaire on 40 respondents taken from a saturated population and the answers were processed using multiple linear regression analysis. The results in this study state that the work environment, organizational commitment, and information technology partially have a positive effect on employee performance.
Estrategia pedagógica enfocada a la mitigación de impactos causados por agroquímicos en cultivos de aguacate hass (persea americana) en la vereda la cristalina (casabianca tolima)
Authors: Parra Maira Alejandra , Monje Ceballes Benigno , Montealegre Giraldo José Fernando
Published: July 2023

La presente investigación titulada: estrategia pedagógica enfocada a la mitigación de impactos causados por agroquímicos en cultivos de aguacate Hass (Persea americana) en la vereda la cristalina (Casabianca - Tolima). Es un trabajo que resulta de la pregunta ¿Cómo sensibilizar por medio de una estrategia pedagógica a la comunidad de la vereda la cristalina sobre la contaminación causada por agroquímicos en el cultivo de aguacate Hass (Persea americana)?. El objetivo general de la investigación es, desarrollar una estrategia pedagógica sobre la huella ecológica que deja la utilización de agroquímicos en el cultivo de aguacate hass como medio de enseñanza para mitigar el impacto que tiene sobre el suelo. El enfoque de la investigación es cualitativo, el alcance es exploratorio y el diseño utilizado fue el de participación acción, el tipo de muestreó de  casos-tipos, esta muestra se centra en la finca la Conga y el Rubí ubicadas en la misma vereda. Para la recolección de datos en el trabajo investigativo, se toma la técnica de entrevista utilizando una guía de entrevista semiestructurada con preguntas abiertas. Para las técnicas e instrumentos de recolección de información, se hacen personalmente las entrevistas a los parceleros y cultivadores.  En la investigación se culmina con presentar la estrategia pedagógica de la forma teórico-práctica a los cultivadores en el mismo lugar de la investigación.  El trabajo finaliza con recolectar información de resultados aplicando nuevamente otra entrevista para su análisis. De allí, se emite como producto algunas conclusiones y recomendaciones.
Design and Preparation of a Novel Antibacterial Hydrogel based on Maleimide-Thiol Conjugation
Authors: Jiang Song , Liu Yue , Wang Taoqing , Gu Yuan , Luo Yige
Published: July 2023

This article synthesized and characterized a novel antibacterial hydrogel, which is formed using maleimide–thiol conjugation. Two precursors chitosan functionalized thiol groups and dextran functionalized maleimide groups prepared and characterized by Nuclear Magnetic Resonance (NMR). Key features of the hydrogel, such as gelation time, swelling behavior, viscoelastic properties, and degradation rate, were thoroughly examined. From gelation time result, we found that formed hydrogel gelation time could be changed with diffident weight percentage of precursors. Based on references, we found the best formular for the gelation and it was also determined for other studies. The swelling study indicated hydrogel has good flexibility and the degradation test indicated hydrogel is biodegradable. The viscoelastic test indicated hydrogel is an elastic solid. Given these attributes, this novel hydrogel has significant potential for use in various biomedical applications. Finally, colony-counting tests revealed that the hydrogel has an excellent antibacterial ability. Given these attributes, this novel hydrogel has significant potential for use in various biomedical applications.
GENETIC BASES FOR IMPROVING THE REPRODUCTIVE AND PRODUCTIVE QUALITIES OF THE SOUTH-KAZAKH MERINOES BRED IN THE DESERT CONDITIONS CHU-ILI LOW MOUNTAINS AND THE MOIYN-KUM SANDS
Authors: Islamov Esenbay , Gulzhan Kulmanova , Kulataev Beibit , Mukhametzharova Ilmira
Published: July 2023

The article reflects the data of scientific research that can serve the practice of selection and breeding work under conditions of various forms of ownership, as well as the improvement of selection and breeding work and the technology of production of high-quality and competitive sheep products in the conditions of year-round use of the foothill-steppe and desert pastures of the south of Kazakhstan.
The research of polymorphism systems of serum proteins of sheep's blood of different intra-breed types by gender and age groups revealed the presence of certain allele combinations and the ratio of transferrin and hemoglobin genotypes. It has been established that these animals have their own specific range of frequencies of occurrence of alleles and combinations of genotypes. Based on the results obtained, the possibility of using genetic blood markers in the early assessment of the productive qualities of animals has been established.
As a result of scientifically based breeding methods, in the “Batai-Shu” LLP in Zhambyl region created a breeding australized herd of the South Kazakh Merino breed with a white wool yolk, a cut of washed wool of 3.1 kg with a yield of 48-50%.