bluuebunny/crossref_metadata_2025 huggingface dataset:
Teaching Digital Citizenship for Vocational Students through “Netizen” Application: its Urgency and Effectiveness
Authors: Wahyudi Diki , Prihatin Titi
Published: August 2023

This study aims to develop a mobile learning-based application, named Netizen, that supports students' independent learning. The research employs a developmental research approach, primarily utilizing the ADDIE instructional design model. The study's findings indicate a positive trend. Specifically, the validation of media and material experts at 84.67% and 96.67%, respectively, illustrates the feasibility of producing Netizen applications. The Wilcoxon test's results, with Asymp.Sig. (2-tailed) of 0.000, are less than <0.05, signifying a significant difference in the average scores of students before and after using the Netizen application. The effectiveness test results reveal a gain score of 0.7052 or 70.52%, classifying it as highly effective. In conclusion, the Netizen application can enhance students' learning processes and outcomes.

Abstrak

Studi ini bertujuan untuk mengembangkan aplikasi berbasis pembelajaran seluler, yang dinamakan Netizen, yang dapat mendukung pembelajaran mandiri siswa. Penelitian ini menggunakan pendekatan penelitian pengembangan, dengan menggunakan model desain instruksional ADDIE sebagai pendekatan utama. Hasil penelitian menunjukkan kecenderungan positif. Secara khusus, validasi dari ahli media dan ahli materi pada tingkat 84,67% dan 96,67%, masing-masing, menggambarkan kemungkinan untuk memproduksi aplikasi Netizen. Hasil uji Wilcoxon, dengan Asymp.Sig. (2-tailed) sebesar 0,000, kurang dari <0,05, menandakan perbedaan yang signifikan dalam skor rata-rata siswa sebelum dan setelah menggunakan aplikasi Netizen. Hasil uji efektivitas mengungkapkan skor kenaikan sebesar 0,7052 atau 70,52%, yang diklasifikasikan sebagai sangat efektif. Sebagai kesimpulan, aplikasi Netizen dapat meningkatkan proses pembelajaran dan hasil belajar siswa.
Using African Indigenous Knowledge in Conceptualizing Peculiarities-Based Teacher Education Curricula for African Universities
Authors: Rufai Saheed Ahmad , Adedeji Luqman Lekan , Musa Bello
Published: August 2023

The dominant nature of Western models of teacher education in African universities has become a subject of great concern. Research reveals that teacher education curriculum models in such universities are either a wholesale importation or partial duplication of some of the dominant models of teacher preparation especially the Teachers College, Columbia and University of Wisconsin, Madison models. Accordingly, such curricula are ostensibly non-African in nature. Consequently, there is a clamour for an African indigenous model with potential to produce African-based teachers for Africa and its Diaspora.  This study which has Indigenous Knowledge as its theoretical basis attempts to formulate university-based Afrocentric teacher education curriculum. The study employs a multiplicity of methods comprising curriculum criticism, the historical method, the analytic method, and creative synthesis. Its significance lies in its potential to contribute to the promotion of the African identity through ideologically independent teachers for ultimate implementation of school curricula in Africa.

Abstrak

Dominasi pendidikan keguruan model Barat di universitas-universitas Afrika telah menjadi perhatian yang besar. Beberapa penelitian mengungkapkan bahwa model-model pengembangan kurikulum pendidikan keguruan sepenuhnya merupakan impor atau duplikasi dari model beberapa model dominan persiapan calon guru, terutama Teachers College, Columbia dan universitas Wisconsin, Madison. Dengan demikian, kurikulum yang dijalankan seolah-olah tidak kontekstual Afrika. Akibatnya, muncul tuntutan lahirnya model asli Afrika yang potensial menghasilkan guru-guru berbasis Afrika untuk Afrika dan diasporanya. Kajian ini menggunakan pengetahuan pribumi sebagai basis teoretik untuk mengembangkan kurikulum pendidikan keguruan berbasis universitas yang menempatkan nuansa dan konteks Afrika sebagai fokus utama. Kajian ini menggunakan beragam metode, antara lain kritik kurikulum, telaah sejarah, metode analitik, dan sintesis kreatif. Signifikansi kajian ini terlatak pada potensinya berkontribusi bagi promosi identitas Afrika melalui guru-guru yang secara ideologis independent untuk mengimplementasikan kurikulum sekolah-sekolah di Afrika secara optimal.
Orchids of the Uniamazonia Botanical Garden (JBUDLA)
Authors: SCA Calderón , TMJ Gasca , MMA Correa , ADA Caicedo
Published: August 2023

The Uniamazonia Botanical Garden (JBUDLA), is located on the campus of the University of Amazonia in Florencia - Caquetá, in the botanical gardens is able to present spaces of great importance as they manage living collections of plants in urban areas generating a suitable environment. It is an ex situ collection that houses different collections of plants with native species of Colombia and other parts of the region. Among the objectives proposed for this work was the recovery of the collection of live orchid plants of the Uniamazonia Botanical Garden, in order to strengthen the special collections of the Uniamazonia Botanical Garden since it did not have this new collection of orchids called Orquideario, These orchids belong to the Orchidaceae family. Field trips, germplasm rescue and planting were carried out in order to enrich the collection with some genera such as Rodriguezia (70), Cattleya (20), Dichaea (40) and Oeceoclades (13).
Plant-mediated noble nanoparticle biosynthesis, characterization approaches, synthesis parameters, and antibacterial action: A review
Authors: Joshi Supriya , Alam Afroz
Published: August 2023

Metallic nanoparticles are receiving more attention as a result of their extensive uses in fields such as health, chemistry, agriculture, and biotechnology, which may be related to their matching small sizes. Because most plants are normally economically, readily accessible, eco-friendly, and harmless, the utilization of plant material for nanoparticle production has increased a lot of traction. The findings of this review are noteworthy because nanoparticle production is different in the properties, types, and physical as well as chemical processes of nanoparticle development for the green development of nanoparticles, their types, and their properties. We have studied in detail the biosynthesis of nanoparticles utilizing extracts from most common plants and their various sections, as well as the various kinds of characterization processes employed for their identification. Numerous current investigations have shown that plant extracts can be used as a non-hazardous precursor for the combining of nanomaterial. Various kinds of reducing and capping/balance factors are abundant in plant extracts. As a result, this approach has great scale-up potential and can generate nanoparticles with a variety of morphologies. Plant-derived NPs are not at most further stable with regards to forming a size and produce a better yield than conventional physical and chemical approaches. As a result, the effect of numerous experimental agents on the size as well as the rate of nanoparticle formation is also discussed. The antibacterial activity of plant-mediated biosynthesized nanoparticles is also discussed in this paper.
In vitro conservation of hops – Cascade and Nugget cultivar under slow-growing conditions
Authors: de Morais Leticia Manuela , dos Reis Camila Audrey , Antonio Ayub Ricardo
Published: August 2023

Hops (Humulus lupulus L.) is economically relevant in the brewing industry. Although Brazil has a big beer market, the unfavorable climate makes the hop growing difficult. Micropropagation is an alternative way to clone plants, but in this process somaclonal subculture variations may occur. In order to reduce consecutive subcultures, the slow growth technique can be used. To develop a slow growth protocol for the conservation of hop plants and Cascade and Nugget cultivars in vitro, Murashige and Skoog (MS) medium was supplemented with doses of osmotic agents: sucrose and sorbitol. The plants were kept at 25°C or 4°C during 120 days. After 4 months, the plants were transferred to a new MS medium containing sucrose (30 g.L-1) and kept for 30 days under optimal growing conditions. After evaluation, the plants were transplanted and underwent a 30-day acclimatization period, and then the ex vitro survival was evaluated. For both cultivars, reduced growth was observed at 4°C, with a satisfactory survival rate. There was no significant interaction between the osmotic agent and temperature for Cascade cultivar Conversely, the Nugget cultivar did have interaction, and the treatment with sucrose (60 g.L-1) at 4 ºC reduced plant length, brought largest root length and fresh mass.
Influence of Salt Intake on Segmental Lesions of Patients with Ischaemic Heart Disease in Sri Lanka: A Cross-sectional Study
Authors: Amadoru Harishchandra , De Silva Rajitha Yasela , Weerasinghe Kariyawasam Don Nandasiri , Gunaratne Maddage Damitha Nandana , Mahesh Pasyodun Koralage Buddhika , Siriwardena Sumudu Prasangi Rupasinghe , Gamage Pasan Malaka , Alles Kaluwelle Mudalige Vishva Randhara , Perera Uduwarage Thilini Randima , Anthonypillai Ravikaran , Suriyaraachchi Vasana , Wijesiri Kankanamge Rasika Nuwan , Liyanage Sajeewanie Nisansala , Malwatta Arunie Kokila , Jayasekara Jayasekara Liyanaarachchige Prasanna , Jayatissa Renuka , Kapuruge Aruna Deshapriya
Published: August 2023

Background: Sodium assists in maintaining body fluid balance. Excess sodium intake increases the risk of ischaemic heart disease (IHD) adding to global and local mortality due to non-communicable diseases. Aim: To determine the salt intake levels of patients having coronary artery bypass grafting (CABG) and to explain the relationship between salt consumption and atheroma development. This study used an adapted cross-sectional design with 233 patients admitted to Sri Jayewardenepura General Hospital with acute heart diseases. Method: Demographic and lifestyle-related data, medical history and food intake data were collected. Salt intake was calculated based on the consumption of salt used per month at household level, salt added to food – including in restaurants. Salt content was determined using web-based applications and food tables. Multivariate logistic regression was used to identify variables significantly associated with IHD. Results: In this study, the daily intake of sodium per person was 6,176 mg. This was much higher than WHO’s recommended level of 2,000 mg/day, demonstrating a significant relationship between segmental lesions and sodium intake (p<0.01). The multivariate binary logistic model demonstrated that high salt intake (OR 8.54; 95% CI [4.545–16.734]) and the presence of diabetes (OR 2.23; 95% CI [1.206–4.238]), contributed to the high number of segmental lesions (p<0.01). Conclusion: A high daily intake of sodium increases the risk of atheroma formation in more coronary segments, regardless of age, sex, several known disease conditions and risk factors.
Adición de inóculos microbianos y condiciones optimizadas de elaboración en un compost comercial
Authors: Castro-Hernández Fernando , Navarro-Flores Juan Ramón , Castro-Barquero Leida
Published: August 2023

Introducción. El compostaje transforma materiales orgánicos residuales en un producto con potencial para restituir materia orgánica y nutrientes para la agricultura, mientras se reduce el volumen y peso de estos materiales y su disposición en rellenos sanitarios o como contaminantes de ríos y mantos acuíferos. Objetivo. Optimizar la producción comercial de compost, con la mejora de las condiciones del proceso y la adición de inóculos microbianos. Materiales y métodos. Sobre un sustrato agroindustrial se optimizaron condiciones del proceso de compostaje, tales como aeración, temperatura, altura de la pila y humedad, y se evaluó la adición de 3 inóculos microbianos degradadores de materia orgánica, para compararlos con un testigo comercial y un testigo absoluto. Se realizaron análisis químicos y microbiológicos, así como de inocuidad, estabilidad y madurez. En total se evaluaron 17 variables químicas, 7 microbiológicas, 2 de inocuidad y 13 de madurez. Para el análisis y comparación de los tratamientos se empleó un método multicriterio y de esa forma resumir el resultado de las 39 variables estudiadas en un solo valor representativo. Resultados. Se establecieron 2 intervalos de confianza, el primero (a) incluye al testigo comercial y al testigo absoluto, con las menores calificaciones de calidad. El segundo (b) abarca a los tratamientos microbiológicos Degradabiol, Bacilos y Agrecicla, con los mayores índices ponderados y las mejores características de calidad. Conclusión. La adición de inóculos, así como el manejo de la humedad, temperatura, volteos frecuentes y altura de hileras, permitió obtener mejores características de calidad, en comparación con el compost producido convencionalmente. La relación C/N deficiente de las materias primas iniciales fue un factor que no pudo ser corregido debido al tipo de residuos usualmente procesados. Es necesario implementar medidas viables para mejorar esta relación, que generalmente es deficiente en las producciones comerciales de compost.
Efecto nutricional foliar de silicio para el cultivo de banano (Musa spp.) en Ecuador
Authors: Sanmartín-Galván Jean , Cuenca-Moreno Andrea , Luna-Romero Ángel , Jaramillo-Aguilar Edison , Villaseñor-Ortiz Diego
Published: August 2023

Introducción. El silicio en banano (Musa spp.) y su nivel crítico al ser aplicado de forma foliar es poco conocido. Por ello, en la presente investigación se propuso como hipótesis que la aplicación foliar de dosis frecuente de ácido monosilicico (SiOH4) incrementa el contenido nutricional del silicio en el cultivo. Objetivo. Evaluar la respuesta del cultivo de banano a dosis crecientes de Si, para determinar el efecto nutricional foliar en las condiciones específicas de la provincia de El Oro. Materiales y métodos. Los ensayos fueron implementados en campo en un diseño experimental en bloques completamente aleatorio, donde se aplicaron dosis crecientes de Si (0; 250; 500 y 750 cm3. ha-1), para evaluar su efecto en el nivel de Si foliar, clorofila y raíces, a partir de análisis foliares y de raíces. Se realizaron análisis de regresión y se obtuvieron los respectivos modelos de relación entre las dosis de Si aplicadas con el nivel de Si foliar en banano y clorofila. Resultados. Se obtuvo que un modelo de regresión lineal (R2: 0,43) que podría ayudar a predecir el nivel crítico de Si foliar en banano. Conclusiones. Se encontró mediante la aplicación de una ecuación lineal que entre mayor sea la dosis de Si aplicada (750 cm3) se lograra un mayor nivel de Si foliar (0,41%) en plantas de banano.
Efecto de tres implementos de labranza sobre propiedades físicas de un suelo andisol en Tierra Blanca, Cartago
Authors: Marín-Araya Silvia , Villatoro-Sánchez Mario Villatoro-Sánchez
Published: August 2023

Introducción. El tipo de implemento y la dirección de la labranza a favor de pendiente han ocasionado que en los suelos hortícolas se presente una importante pérdida de suelo. El problema ha generado una pérdida de los horizontes más productivos y detrimento de las propiedades físicas del suelo. Objetivo. Determinar el efecto que ejercen el palín mecánico, la rastra rotativa y el rotador, sobre la densidad aparente, porosidad y estabilidad de agregados de un suelo Andisol bajo 2 ciclos no continuos de cebolla en Tierra Blanca, Cartago. Materiales y métodos. Los 3 implementos fueron utilizados en la preparación del suelo para el cultivo de cebolla (Allium cepa L.). Se realizaron evaluaciones en la prelabranza del ciclo 1, al final del primer ciclo de cultivo, en la prelabranza del ciclo 2 y al final del segundo ciclo de cebolla. Se evaluaron las variables de densidad aparente, porosidad y estabilidad de agregados. Resultados. Se encontró que el suelo, durante el estado de barbecho, presentó una densidad aparente relativamente alta, con porosidad y estabilidad de agregados bajas. Con la labranza, disminuyó la densidad aparente, aumentó la porosidad del suelo e incrementó la estabilidad de agregados durante los diferentes momentos de evaluación. Conclusión. Los cambios encontrados son una consecuencia de la reorganización de la estructura del suelo, producto de la labranza, cuando se sale de un periodo de barbecho.
Efecto del uso de una mezcla de compuestos gluconeogénicos en vacas lecheras en transición
Authors: Arita-Portillo Carlos Rafael Arita-Portillo , Elizondo-Salazar Jorge Alberto
Published: August 2023

Introducción. Durante el periodo de transición las vacas lecheras sufren grandes cambios metabólicos, ocasionados por el final de la gestación y el inicio de la lactancia. Durante este periodo la mayoría de vacas presentan un balance energético negativo, debido a la reducción en la ingesta de materia seca y un aumento de los requerimientos energéticos, que induce a la movilización de tejido adiposo y una consecuente cetogénesis, asociada con un menor aporte de glucosa a nivel hepático y menor capacidad oxidativa de ácidos grasos no esterificados en este órgano. Objetivo. Evaluar el efecto de la inclusión de una mezcla de compuestos gluconeogénicos (propilenglicol, propionato de calcio y propionato de sodio) sobre los parámetros productivos de vacas en transición. Materiales y métodos. El estudio se desarrolló en San Carlos, Alajuela, Costa Rica de junio a octubre de 2020. Se ofrecieron 400 g de la mezcla de compuestos gluconeogénicos desde los 21 días antes de parto hasta los 21 días posparto. Se utilizaron 18 vacas multíparas a las que se les asignó aleatoriamente uno de los 2 tratamientos: vacas que consumían la mezcla de compuestos gluconeogénicos (PG) y vacas que no consumían dicha mezcla (TG). Se midió el peso vivo, la condición corporal, las concentraciones de glucosa y β-hidroxibutirato en sangre, la producción de leche y sus componentes. Resultados. El tratamiento no afectó el peso vivo, la condición corporal ni la producción de leche. Se observaron diferencias significativas en las concentraciones de glucosa 7 días antes del parto, siendo mayores para las PG que para TG (p<0,05). Las concentraciones de betahidroxibutirato fueron mayores para TG que para PG (p<0,05) los días 7 y 21 posparto. La concentración de sólidos totales y grasa en la leche fueron mayores para TG que PG (p<0,05) en el día 7 posparto. Conclusión. Los resultados sugieren que suplementar con una mezcla de compuestos gluconeogénicos mejora el balance energético de vacas en transición.
First record of Aulacaspis tubercularis (Hemiptera: Diaspididae) in Costa Rica, a scale insect affecting mango (Mangifera indica) in Alajuela urban environments
Authors: Solano-Gutiérrez Minor , Hanson-Snortum Paul
Published: August 2023

Introduction. Mango (Mangifera indica L.) is widely cultivated around the world and in Costa Rica nearly 8200 hectares are dedicated to the production of this crop. More than 400 species of phytophagous insects and mites have been reported on mango worldwide. Among them are around 73 species of armored scale insects (Hemiptera: Diaspididae), of which Aulacaspis tubercularis Newstead is one of the most serious pests of mangos in many parts of the world. Objective. In the present work, we report for the first time the occurrence in Costa Rica of the white mango scale, A. tubercularis. Materials and methods. Mango tree samples were collected in San Rafael, a town located in the central canton of Alajuela province in the Greater Metropolitan Area of Costa Rica. Insects found on leaves were examined under a stereomicroscope, counted and classified according to the condition of their wax covers, which provided evidence of activity by natural enemies. Slide mounts of adult females were prepared and examined under a light microscope. Results. The armored scale was identified as A. tubercularis and the frequency of occurrence on the mango trees sampled was 90%, where 12% of adult females showed evidence of predation and 2.5% showed evidence of parasitization. Conclusion. A. tubercularis was recorded for the first time in Costa Rica. Further investigations on the population dynamics and natural enemies are needed to provide useful information in order to implement adequate control strategies.
Masonería, resistencia y rescate de los judíos en Dinamarca (1943)
Authors: Fragale Luca Irwin
Published: August 2023

Este estudio trata sobre una convivencia exclusive. En el apogeo de la amenaza nazi sobre Europa,solo en Dinamarca podemos observar simultáneamente:
a) una masonería libre y oficialmente activa.b) un movimiento de resistencia.c) una operación de ayuda organizada para los judíos que escapaban.La masonería llevó a cabo una actividad clandestina durante los regímenes totalitarios europeos,a pesar de que oficialmente sobrevivió solo en Dinamarca (e Islandia), Suecia, Reino Unido, Irlanday Suiza. Esta investigación trata de arrojar luz sobre la probable participación de la masoneríadanesa en ese rescate de los judíos daneses y en el movimiento de resistencia.
lectura retrospectiva de los masones, las masonas y la masonería en Costa Rica
Authors: Martínez Esquivel Ricardo
Published: August 2023

Este artículo analiza el papel de la masonería como agente de cambio en la historia de Costa Rica. El texto se divide en cinco partes: los intentos de organización de logias en Centroamérica antes del establecimiento en 1865 sustentado con fuentes primarias; la relación masonería y modernidad; la antimasonería; la relación masonería y esoterismo; y la bibliografía sobre la masonería en Costa Rica.
GEODATA IN SCIENCE – A REVIEW OF SELECTED SCIENTIFIC FIELDS
Authors:   Institute of Earth Sciences, University of Silesia in Katowice, Będzińska 60, 41-200 Sosnowiec, Poland, Apollo Michal , Jakubiak Mateusz ,   AGH University of Krakow, Mickiewicza 30, 30-059 Krakow, Poland, Nistor Sorin ,   Faculty of Construction, Cadastre and Architecture, University of Oradea, 410058 Oradea, Romania, Lewinska Paulina ,   AGH University of Krakow, Mickiewicza 30, 30-059 Krakow, Poland, Krawczyk Artur ,   AGH University of Krakow, Mickiewicza 30, 30-059 Krakow, Poland, Borowski Łukasz ,   Faculty of Forestry, University of Agriculture in Krakow, 29 Listopada 46, 31-425 Krakow, Poland, Specht Mariusz ,   Department of Transport and Logistics, Gdynia Maritime University, Morska 81-87, 81-225 Gdynia, Poland, Krzykowska-Piotrowska Karolina ,   Faculty of Transport, Warsaw University of Technology, Koszykowa 75, 00-662 Warsaw, Poland, Marchel Łukasz ,   Department of Transport and Logistics, Gdynia Maritime University, Morska 81-87, 81-225 Gdynia, Poland, Pęska-Siwik Agnieszka ,   AGH University of Krakow, Mickiewicza 30, 30-059 Krakow, Poland, Kardoš Miroslav ,   Faculty of Forestry, Technical University in Zvolen, T.G. Masaryka 24, 960 01 Zvolen, Slovakia, Maciuk Kamil ,   AGH University of Krakow, Mickiewicza 30, 30-059 Krakow, Poland
Published: August 2023

Aim of the study: Today, completely new forms of geo-information systems are becoming increasingly popular. New technological possibilities allow these systems to be adapted to the requirements and needs of societies. This paper is an extensive literature review of the use of geodata in various scientific fields, in STEM (science, technology, engineering, and mathematics) disciplines. However, as there is no universal agreement as to which disciplines are included in the STEM, the authors also included related fields such as geography or transport. Material and methods: Already a preliminary analysis of the Web of Science Core Collection database has shown that geodata is used very widely, in every scientific discipline analysed (with varying degrees of sophistication). The main objective of the paper is to provide a comprehensive analysis of the usage of geodata in five areas: bathymetric measurements, satellite geodata, aerial retrieved geodata, levelling networks, and GIS data. Results and conclusions: The results showed the increasing availability of data that can contribute to a better understanding and management of our planet. Geodata as a tool is overly broad and general, and it is used or might be used in every discipline of science.
Sensitive, non-immunogenic in vivo imaging of cancer metastases and immunotherapy response
Authors: Merrill Joseph R. , Inguscio Alessandra , Chung Taemoon , Demestichas Breanna , Garcia Libia A. , Habel Jill , Lewis David Y. , Janowitz Tobias , Lyons Scott K.
Published: August 2023

Non-invasive imaging of tumors expressing reporter transgenes is a popular preclinical method for studying tumor development and response to therapy in vivo due to its ability to distinguish signal from tumors over background noise. However, the utilized transgenes, such as firefly luciferase, are immunogenic and, therefore, impact results when expressed in immune-competent hosts. This represents an important limitation, given that cancer immunology and immunotherapy are currently among the most impactful areas of research and therapeutic development. Here we present a non-immunogenic preclinical tumor imaging approach. Based on the expression of murine sodium iodide symporter (mNIS), it facilitates sensitive, non-invasive detection of syngeneic tumor cells in immune-competent tumor models without additional immunogenicity arising from exogenous transgenic protein or selection marker expression. NIS-expressing tumor cells internalize the gamma-emitting [99mTc]pertechnetate ion and so can be detected by SPECT (single photon emission computed to-mography). Using a mouse model of pancreatic ductal adenocarcinoma he-patic metastases in immune-competent C57BL/6 mice, we demonstrate that the technique enables the detection of very early metastatic lesions and longitudinal assessment of immunotherapy responses using precise and quantifiable whole-body SPECT/CT imaging.
FORECASTING THERMAL ENERGY DEMANDS FOR VARIOUS PROCESS INDUSTRIES USING MACHINE LEARNING TECHNIQUES
Authors: Gond Shivanand , Krishnan Naveen , K. Ravi Kumar
Published: August 2023

Despite the fact that India has vast solar energy potential, the process industries are dependent on conventional fossil fuels for their thermal energy needs. Solar thermal energy is a viable option for industrial process heating applications to mitigate the utilization of conventional fossil fuels. The utilization of solar energy in the process industries to meet their energy demands helps to reduce the carbon footprint, and eventually will help India balance its energy needs by reducing the import of crude oil. The exploitation of solar energy in the process industries requires the assessment of future thermal energy demands. In this study, since the data points were nonlinear in nature, support vector regression (SVR) and long short-term memory (LSTM) algorithms were applied to forecast the thermal energy demands of various process industries. The process industries considered in this study were textile, food processing, leather and footwear, chemical and pharmaceutical, dairy, iron and steel, and automotive. Data from 1998 to 2014 were used for training and data from 2015 to 2017 were used for testing. The mean absolute percentage error (MAPE) was used as a performance measure metric to measure the performance of the SVR and LSTM algorithms. The average MAPEs obtained for given industries by the SVR with the genetic algorithm (SVRGA), SVR with grid search (SVRGS), and LSTM algorithm were 7.56%, 8.34%, and 11.10% respectively. The SVRGA outperformed the SVRGS and LSTM algorithm for the given training and testing data.
Okuma Çemberi Yönteminin Öğrencilerin Okuma Tutumlarına ve Eleştirel Okuma Becerisine Etkisi
Authors: DEMİR Erhan , PİLAV Salim
Published: August 2023

Bu araştırmanın amacı, ortaokul yedinci sınıf öğrencilerinin okumaya ilişkin tutumlarına, eleştirel okuma becerilerine okuma çemberi yönteminin etkisini belirlemektir. Çalışmada ön test-son test kontrol gruplu yarı deneysel desen kullanılmıştır. Araştırma katılımcılarını Kırıkkale ili Yahşihan ilçesinde bir devlet ortaokulunda öğrenim gören 17’si kontrol, 17’si deney grubunda olmak üzere toplam 34 yedinci sınıf öğrencisi oluşturmaktadır. On iki haftalık uygulamada deney grubuna okuma çemberi kullanılırken kontrol grubuna planlı herhangi bir eleştirel okuma eğitimi verilmemiştir. Araştırmanın nicel verilerini elde edebilmek için Ünal (2006) tarafından geliştirilen “Eleştirel Okuma Ölçeği” ve “Okumaya İlişkin Tutum Ölçeği” kullanılmıştır. Nicel veriler Mann-Whitney U ve Wilcoxon İşaret Testiyle değerlendirilmiştir. Bulgulara göre okuma çemberinin yedinci sınıf öğrencilerinin okumaya ilişkin tutum ve eleştirel okuma puanlarında küçük de olsa bir artış sağladığı ancak bu artışın istatistiksel olarak anlamlı olmadığı belirlenmiştir. Bu kapsamda okuma çemberi uygulamalarının daha kalabalık gruplarla ve daha uzun süreli uygulanması önerilebilir.
Archive, Intertextuality and Genre in Percival Everett’s The Trees (2021)
Authors: Keeble Arin , Harrison Sheri-Marie
Published: August 2023

This article reads Percival Everett’s The Trees (2021) as a novel of racial terror that is both about the reading and interpreting of an archive of this violence and, in some senses, formally archival, too. Drawing on Theodore Martin’s theory of the “drag of genre” and “drift of the contemporary,” we consider the ways Everett’s novel modulates through different generic modes while critiquing and disrupting the ideological currents that move within them and normalize violence via generic conventionality. In The Trees, an extensive set of allusions complement the inherent intertextuality of the crime and gothic genres to form an archive which is further constituted by a literal (fictional) archive at the heart of the novel. This archive, kept by an elderly root doctor, features “almost everything ever written about every lynching in these United States of America since 1913” (103). From this point we draw on Saidiya Hartman’s and Toni Morrison’s critiques of the archives of slavery and an American literary archive, respectively, locating Everett’s project as a timely intervention that rightly positions state and state-sponsored terrorism at the heart of America’s history.
Surgical correction of omphalocele in local goat breed (Beetal) of Jhang, Punjab: A case study
Authors: Ali Raza , Wajeeha Saeed , Abdul Mateen , Aun Muhammad , Farah Ijaz , Amanullah Khan
Published: August 2023

Omphalocele is a rare congenital condition where closure defects in the abdominal wall at the umbilical ring lead to the protrusion of intestinal or other visceral organs, covered by a thin epithelial layer. The developmental mechanism of this condition is not fully understood, and various theories have been proposed to explain it. This study presents a case of omphalocele in a newborn female black goat kid, detailing its clinical presentation, surgical management, and postoperative care. The surgical procedure involved meticulous preparation of the surgical site, administration of local anesthesia, and careful repositioning of the intestines, liver, and a portion of the spleen. Excess skin and the amnion membrane were removed to facilitate safe repositioning, and the umbilical ring was excised to widen the opening. The abdominal wall layers were meticulously closed using appropriate suture materials. The kid’s postoperative recovery was uneventful, with normal vital signs, fecal passage, and feeding behavior observed. The study discusses omphalocele in comparison to other abdominal abnormalities and explores potential developmental mechanisms. The authors emphasize the importance of immediate surgical intervention despite varying prognoses associated with this condition. The study underscores the significance of surgical treatment for omphalocele cases in newborn goat kids, providing hope for affected animals and valuable insights for veterinary professionals. Although the exact prevalence of omphalocele remains uncertain due to unreported cases, this report demonstrates successful surgical correction and the potential for curing the condition if diagnosed and treated promptly. Further research is needed to fully understand the genetic and environmental factors contributing to omphalocele and its impact on livestock.
Processing frozen cells for population-scale SQK-LSK114 Oxford Nanopore long-read DNA sequencing SOP v1
Authors: Cogan Guillaume , Alvarez Jerez Pilar , Malik Laksh , Blauwendraat Cornelis , J Billingsley Kimberley
Published: August 2023

Abstract As part of the GP2 initiative we will generate long-read sequencing data for ~1000 samples to better understand the genetic architecture of Parkinson's disease. To generate this large-scale Nanopore data we have developed a protocol for processing and long-read sequencing frozen human blood samples, targeting an N50 of ~30kb and ~30X coverage. †Correspondence to: Kimberley Billingsley billingsleykj@nih.govAcknowledgements:We would like to thank the Nanopore team (Jade Bartolo, Olivor Holman, Androo Markham & Jessica Anderson) and the whole CARD long-read team listed below => UCSC: Benedict Paten, Trevor Pesout, Paolo Carnevali, Mira Mastoras, Melissa Meredith, Jean Monlong, Ryan Lorig-Roach, Mobin Asri; NE: Miten Jain; NCI: Mikhail Kolmogorov; NHGRI: Adam Phillippy, Arang Rhie; Baylor: Fritz Sedlazeck, Farhang Jaryani; JHU: Winston Timp; NIA: Cornelis Blauwendraat, Kimberley Billingsley, Pilar Alvarez Jerez, Laksh Malik, Breeana Baker, Maysa Abdelhalim, Kensuke Daida, Rylee Genner, Abigail Miano-Burkhardt, Guillaume Cogan, Caroline Pantazis;
PHYTOMap in Arabidopsis root tips v1
Authors: Nobori Tatsuya
Published: August 2023

Retrieving the complex responses of individual cells in the native three-dimensional tissue context is crucial for a complete understanding of tissue functions. Here, we present PHYTOMap (Plant HYbridization-based Targeted Observation of gene expression Map), a multiplexed fluorescencein situhybridization method that enables single-cell and spatial analysis of gene expression in whole-mount plant tissue in a transgene-free manner and at low cost. We applied PHYTOMap to simultaneously analyze 28 cell type marker genes inArabidopsisroots and successfully identified major cell types, demonstrating that our method can substantially accelerate the spatial mapping of marker genes defined in single-cell RNA-seq datasets in complex plant tissue. [Reagents] DPBST 0.1% (vol/vol) Tween-20 in 1x DPBS DPBSTR DPBST + 1:100 SUPERaseIN Cell wall digestion enzyme solution (CWDES; 10x stock) 250 mg macerozyme, 250 mg cellulase, 500 mg pectinase in 50 mL Nuclease-free water. Filter sterilize (0.22 μm filter) and store aliquots of 1 mL at -20°C. Proteinase K buffer ABReagentAmount10x equiPhi29 DNA polymerase buffer10 µL10 mM dNTP2.5 µL4 mM aminoallyl-dUTP0.5 µLBSA (20 mg/ml)0.5 µLDTT (100 mM)1 µLSUPERase IN1 µLNuclease Free Water 84.5 µL FAA ABReagentAmount1M Tris-HCl (pH 8.0)5 mL0.5 M EDTA (pH 8.0)5 mLNuclease Free Water up to 50 mL
Sensory perception and consumer profile in relation to bovine meat packed in modified atmosphere packaging
Authors: Puel A. C. , Carvalho S. R. S. T. , Pereira M. C. , Pickler L. , Sperandio A. R. , Lima A. L. F.
Published: August 2023

The objective of the present study was to evaluate the influence of the socioeconomic profile of 338 people who answered questions about knowledge, consumption, determining factors in the acquisition, frequency of consumption, place of purchase, evaluation of general aspects by the consumer and repetition of the purchase of beef packed with modified atmosphere packaging (MAP). The generalized linear model methodology, GENMOD, was used with a probit link function to test the interaction of the questions with the socioeconomic profile and for all significant variables. The risk was calculated using the odd ratios (OR) with a confidence interval of 95%. Only age and education influenced consumers' disposition regarding the questions raised in the questionnaire. Most of the people who answered the questionnaire had never consumed any product packaged with MAP, but they are very interested in trying it out. Among consumers who had already consumed some product packaged with MAP, the vast majority consumed beef. Consumers over the age of 50 showed a greater tendency to consume beef with MAP more than once a week. Appearance was the main factor for decision making during the purchase and the supermarket is the main place of purchase of the product. The vast majority of consumers liked and would buy beef packed with MAP again.
Features of pregnancy course in patients with thrombophilia and abnormal placenta location
Authors: Zubenko V. B. , Lovkova A. I.
Published: August 2023

Aim: to identify inherited and acquired thrombophilia as well as features of pregnancy course in women with abnormal placenta location.

Materials and Methods. Within the framework of a prospective controlled cohort non-randomized, interventional study there was analyzed pregnancy course in 135 women with abnormal placenta location: group I – 42 patients with abnormal placenta location in history; group II – 61 women with placenta previa detected during ongoing pregnancy; group III – 32 patients with placenta previa detected both in ongoing and previous pregnancy. The control group consisted of 120 pregnant women with normal placenta location without a previous complicated obstetric history. All patients underwent clinical examination of pregnancy course assessing fetus intrauterine growth retardation (IUGR) and fetal biophysical profile; inherited and acquired thrombophilia were identified – analyzing circulating antiphospholipid antibodies (APAs) by ELISA, inherited thrombophilia by polymerase chain reaction to identify mutations in genes encoding 5,10methylenetetrahydrofolate reductase (MTHFR), G20210A mutations in prothrombin gene, V Leiden mutation, polymorphismin fibrinogen and plasminogen activator inhibitor 1 (PAI-1) genes.

Results. Inherited thrombophilia was detected in 101 (74.81 %) pregnant woman with abnormal placenta location: group I – in 31 (73.8 %) patients, group II and group III – in 44 (72.1 %) and 26 (81.3 %) patients, respectively. Inherited forms of thrombophilia were detected in 29 (24.2 %) women from control group. Multigenic forms of thrombophilia peaked in group III (14/43.8 %), followed by group I (16/38.1 %) and group II (23/37.7 %). In the control group, multigenic thrombophilia was detected in 16 (13.3 %) women. Selective inherited thrombophilia and АРАs circulation were detected in 30 (22.22 %) women with abnormal placenta location: group I – in 8 (19.0 %) patients, group II – in 13 (21.3 %), and group III – in 9 (28.1 %) cases. In the control group, there were only 8 (6.7 %) such patients. Patients with IUGR signs were identified in all study groups: 4 (9.52 %) in group I, 6 (9.84 %) in group II, 6 (18.75 %) in group III as well as in control group in 6 (6.67 %) women.

Conclusion. Pregnancy management in patients with thrombophilia and placental abnormalities should be accompanied by an proper fetal assessment (biophysical profile) and, in some cases, anticoagulant or antiplatelet therapy. However, insufficient number of cases requires to conduct further investigations to assess a relation between thrombophilia, placenta previa and a risk of obstetric complications particularly IUGR.
Original Guide for Minimally Invasive Distal Osteotomy of the First Metatarsal Bone in the Treatment of Hallux Valgus
Authors: Oleinik Aleksey V. , Belenkiy Igor G. , Sergeev Gennadiy D. , Kochish Aleksander Yu. , Razumova Kseniya V. , Binazarov Artur E. , Maiorov Boris A.
Published: August 2023

Background. Minimally invasive surgical interventions are widely used in trauma and orthopedic surgery. Both the surgical technique and the instruments applied are being improved, which contributes to better functional results of patients’ treatment.
Aim of the study — to present a new guide tool for minimally invasive surgical correction of acquired hallux valgus.
Guide description. A guide tool intended to be used in minimally invasive surgical interventions for hallux valgus (HV) correction has been developed. It consists of several interconnecting components: the distal bar, the intramedullary guide, the proximal bar, and the wire guide. These components are fixed to each other. At the same time, the distal bar, the proximal bar, and the wire guide are connected with the possibility of adjusting their mutual positioning. The design of the proposed device enables to guide the first guiding wire and to place the cannulated screw in an optimal position. The presented clinical case illustrates the successful application of the described device. The patient underwent minimally invasive distal corrective osteotomy for hallux valgus of medium severity. According to the preoperative X-rays, the first intermetatarsal angle and the first toe deviation angle were 13.5° and 25°, respectively. Six months after the surgery, they were 3° and 7°, respectively. The result of the corrective surgery was considered excellent.
Conclusion. Application of the proposed guide tool decreases surgery duration, reduces soft tissue damage and minimizes radiation exposure of the surgeon and the patient.
A New Paradigm for Structural Characterization, including Rotational Measurements at a Single Site
Authors: Rossi Yara , Tatsis Konstantinos , Clinton John , Chatzi Eleni , Rothacher Markus
Published: August 2023

In this article, we demonstrate that a single station can be used to measure the dynamic properties of a structure. The station includes a collocated accelerometer and rotational sensor, hence, can record both three-component translation and three-component rotation and is referred to as the 6C-station within this study. The key advantage of this approach is to provide a fast and simple path to a comprehensive structural health monitoring characterization that is comparable to the use of a traditional approach using a horizontal array of three-component accelerometers. The deployment of newly developed high-quality rotational sensors allows the direct measurement of structural rotations, facilitating the extraction of structural mode shapes. In this work, we show how an established system identification tool, stochastic subspace identification, can be applied to the 6C-station data and characterize modal properties and structural response. Our results are verified and contrasted against standard horizontal and vertical array configurations. The Prime Tower, a high-rise structure in Zürich, serves as a case study. A structural characterization of this building is presented for the first time. We show that a 6C-station is capable of defining the frequencies of this stiff high-rise building with a fidelity that is on par with a five-sensor horizontal array. The mode shapes of the roof can be precisely determined with a confidence margin that is comparable to conventional sensing array solutions. However, the effectiveness of using only a 6C-station is determined by the noise level of the sensors—in particular, the rotational seismometer needs to be of high quality. The results indicate that, owing to the collocation measurement of translation and rotation, a 6C-station can deliver a comprehensive structural monitoring solution with minimum time, effort, and footprint.
Research and the elderly: Do we need fair practices of ethics?
Authors: John Bindu
Published: August 2023

Changing demographics have brought a dramatic increase in the need for research in the health care of the population, and understanding and countering opportunities and challenges presented by an aging population, and the process of aging, for enhancing the positive aspects of aging. It is also envisaged that the knowledge brought through research on the elderly has a large potential for improving individual lives and society. Since the elderly population represents a vulnerable group, it is thus required that research is conducted following ethical principles and proper protocols. This article examines various aspects involved in evidence-based research on the elderly.
Immunological response in health care workers post COVID-19 vaccination
Authors: Sidhu Shailpreet Kaur , Singh Kanwardeep , Kaur Savjot , Jairath Mohan , Kaur Amandeep
Published: August 2023

To curb SARS-CoV-2, various vaccines received Emergency Authorization Use by copious agencies. These vaccines are administered to health-care workers, front-line workers, elderly individuals and many others. Health care workers were the first to be administered with vaccines, thus, evaluating the antibody response helps to portray a picture of the burden of SARS-CoV-2 infection amid Health Care Workers.

The present study aimed to investigate the production of total antibodies against SARS-CoV-2 before and after vaccination (2 doses) among Health Care Workers along with associated factors. The present study was conducted on 60 healthcare workers as cases who got vaccinated for COVID-19. The semi-quantitative detection of anti-SARS-CoV-2 IgG Ab in the samples was detected using Erba Lisa COVID-19 total antibody indirect ELISA kit using standard protocol as described by the manufacturer.

In the present study, co-morbidities such as hypertension was presented in only 8 (12.3%) individuals, diabetes in 4 (6.1%) and Coronary Artery Disease in 1 (1.5%). After first dose of administration, 86.67% HCWs were found seropositive for the anti-SARS-CoV-2 Ab while 13.33% were seronegative, however, after second dose 100% seroprevalence was observed amid HCWs. The statistical analysis depicted a significant difference (p<0.0001) in antibody titres among individuals before and after vaccination. The mean of total antibody levels detected at zero week was (4.1), 4th week, (39.09), 8th week (79.39) and 12th week (105).

The present study provides important information on the detectable levels of antibodies induced by COVISHIELD against the SARS-CoV-2 which was independent of gender and age.
A comparative study of hearing outcome in cholesteatoma surgery canal wall up versus canal wall downmastoidectomy in 100 patients
Authors: Rameshbhai Trupti Savariya , Damjibhai Alpesh Fefar
Published: August 2023

Cholesteatoma is a well-demarcated sac of keratinizing squamous epithelium in the temporal bone, which is commonly characterized as “skin in the wrong place. The major goal of surgery for cholesteatoma is to make the ear safe and dry with increasing concern of the hearing outcome of patients. Two main surgical techniques employed are Canal Wall down (CWD) and Canal Wall up Mastoidectomy (CWU). In the current study, an attempt would be made to evaluate which technique would be better for achieving disease clearance with favorable hearing outcome and dry ear.

1. To evaluate the hearing results following CWU and CWD surgery in patient with cholesteatoma.2. To decide surgical approach according to extension of disease.Materials and Methods:This is a prospective study involving 100 patients with cholesteatoma who had undergone CWD and CWU surgery over the period of 3 years.The choice of mastoidectomy, CWD or CWU, was the decision of the surgeon, after completely evaluating the patient, preoperatively and intraoperatively. All cases were followed up & assessed by autoscopic examination & PTA for minimum of 3 months.

In the CWD group, mean hearing gain, in 3 months was 12±1.73dB. In the CWU group, hearing gain in 3 month postoperative period was 18±2.06 dB. Also the hearing gain between the two groups was compared and it was found to be statistically significant for the 3 months (p=0.0002) postoperatively; signifying that there was a comparable difference for CWU over CWD mastoidectomy in the matter of Hearing Gain. SNHL was also seen post operatively in both group. Total 3 (6%) patient in CWU had SNHL post operatively in comparison to 7(14%) patients in CWD.

From our study results, we think that CWU is superior to the CWD surgery in cases of cholesteatoma because of good post-operative hearing outcome as well as less complication and law morbidity. CWD surgery should be used in cases of extensive cholesteatoma, mental retardation, not sure about follow up and inadequate middle ear space cases.