bluuebunny/crossref_metadata_2025 huggingface dataset:
ASSESSMENT OF TREATMENT OUTCOMES OF UNSTABLE INTERTROCHANTERIC FRACTURES WITH PROXIMAL FEMORAL NAIL
Authors: A. Kamble Sudarshan , Gupta Anurag
Published: February 2024

Background: Intertrochanteric fractures commonly manifest in elderly individuals with diminished bone strength and density. The Proximal
Femoral Nail is advantageous due to its positive biomechanical qualities, which provide enhanced mechanical stability and allow for early weight
bearing. Present study is aimed to assess treatment outcomes of unstable intertrochanteric fractures with proximal femoral nail. The Methodology:
present prospective study was conducted on 30 cases of unstable trochanteric fractures admitted under department of orthopaedics, tertiary care
hospital, Maharashtra. Patients >18 years of age presenting to our causality with intertrochanteric femoral fractures with all Boyd and Grifn types
(1-4) with displaced and un-displaced fractures with less than 1 week duration and without any other associated fractures were included. Functional
outcome Intertrochanteric fractures treated by Proximal Femoral Nailing were analysed using Harris Hip Score. Data was analysed using SPSS
version 21. Chi-square test was used to compare qualitative variables and quantitative variables were presented as mean and standard deviation. P
value <0.05 was considered signicant at 95% condence interval. Results:In the present study, out of 35 patients,60% were males. Mean age was
64.82±7.36 years. Mode of injury was RTA (Road trafc accident) in 37.14%. As per Boyd and grifn fractures classication types, most common
was type 2 in 12 (34.29%) patients. Lower age was associated with better outcomes (p value 0.039). Lesser duration between trauma to Surgery was
found to be associated with better outcomes (p value 0.001). Majority of the patients had union between 12 to 14 weeks (37%) followed by 34% in <
12 weeks. Lower age was associated with early union time (p value 0.002). Lower types (type 1 and type 2) of Boyd and Grifn classication had
lesser duration of union (p value 0.363). The type 1 fractures united in <15 weeks and one patient with type 1 and three patient from type 3 class had
union time 15 to 16 weeks but the association was not signicant (p value 0.254). Pain at trauma site (hip pain) and Bedsores were most common
complications seen in 5 (14.29%) patients each. Surgical Site Infection was observed in 3 (8.57%) patients which were managed with debridement
and antibiotics. Conclusion: The utilisation of the proximal femoral nail (PFN) in the management of unstable intertrochanteric fractures has
demonstrated a more advantageous prognosis, establishing it as the preferred implant for such fractures in current practice.
ANALYSING THE OUTCOME OF PROXIMAL FEMORAL NAILING IN UNSTABLE INTER-TROCHANTERIC FRACTURES
Authors: Ayalani Nitesh , Ahirwar Premchand , Saryam Nandram
Published: February 2024

Background :- The purpose of the present study was to analyse the outcome of proximal femoral nail in unstable inter-trochanteric fractures
according to Evans classication and also whether it actually altered the eventual functional outcome of the patient. Methods:-Thirty patients with
fresh unstable inter-trochanteric fractures who were operated within 21 days of injury were recruited in the present study conducted in the
Department of Orthopaedics, Unique super-speciality Hospital, from Dec. 2018 to Dec. 2020.Age Most of the patients in study belong to age group
51-60 years. Results:-We include all unstable fracture in our study. Thirty patients treated with PFN were included in the study. Majority of the
patient in our study were between 51-70 years with a mean age of 51.9 years.The PFN required shorter incisions, less blood loss and operative
times. The average Harris hip score came out to be 88 and 50% of the patients belonged to the 'excellent' group that was Harris hip score more that
90.Unstable inter-trochanteric fractures, treated with PFN, had signicantly better outcomes with all patients having excellent results.
Conclusion:- We conclude that proximal femoral nail is a very good implant in treating unstable intertrochanteric fracture as it is a closed
procedure.
ANGIOGRAPHIC PROFILES OF DENOVO CORONARY ARTERY DISEASE IN PATIENTS WITH DIABETES MELLITUS AND WITHOUT DIABETES MELLITUS: AN OBSERVATIONAL, COMPARATIVE STUDY
Authors: Samad Shadab , Puri Piyush , Anand Puneet , Kachhadia Meet Popatbhai , Ratnani Tanya , Sardana Princy , S. Arora Rajpreet , Prachi FNU , Bhagat Ridhi , Singla Deepak , Puri Arun
Published: February 2024

Diabetes mellitus, particularly type 2 (T2DM), is a signicant global health concern with a strong correlation to coronary artery disease (CAD),
particularly in India. The associated risk factors include hypertension, age, dyslipidemia, obesity, physical inactivity, and stress. Complications
from CAD account for most deaths and hospitalizations among diabetics. This study was conducted to understand the relationship between
diabetes and de novo CAD in the Indian population using angiography prole and syntax scoring.
PREVALENCE OF ACUTE KIDNEY DAMAGE SECONDARY TO DIABETIC KETOACIDOSIS IN A POPULATION BELONGING TO THE ISSSTE CLINICAL HOSPITAL CELAYA, MEXICO
Authors: Escudero Farías Ramiro , Sánchez Reséndis Óscar , Gaspar Cisneros Julio César , Vázquez Bravo Christian
Published: February 2024

Mexico is on the list of the 10 countries with the highest number of people living with Diabetes Mellitus. This disease causes blindness, chronic
kidney problems, non-traumatic amputations, and is one of the 10 most frequent causes of hospitalization in adults. On the other hand, diabetic
ketoacidosis is one of the acute complications of Diabetes Mellitus, and it is caused by insulin deciency, characterized by a metabolic disorder,
consisting of three concurrent abnormalities: hyperglycemia, hyperketonemia, and metabolic acidosis, which commonly leads to deterioration of
kidney function and death. In this research, 24 patients (15 female, 9 male) were observed, and related to the prevalence of acute kidney injury
secondary to diabetic ketoacidosis. The results show that female patients were the most prevalent, with 15 cases (62.5%), while males made up a
total of 9 cases (37.5%). The median age for females is 67.5 years, with a minimum age of presentation of 50 years; for males the median age is 71.5
years, with a minimum age of presentation 45 years. It should be noted that in 100% of these, with adequate uid therapy, they achieved remission
of AKIN, without evolving into chronic kidney disease.
DETERMINANTS OF HOUSEHOLD VULNERABILITY TO FOOD INSECURITY IN BANGUI AND ITS SURROUNDINGS
Authors: BELDO Bertrand , MBETIDBESSANE Emmanuel
Published: February 2024

The objective of this research is to analyze the determinants of household vulnerability to food insecurity in Bangui and its surroundings. To
achieve this objective, a sample of 200 households was randomly selected, taking into account the demographic weight of the districts and
municipalities. The surveys involve heads of households and their wives in the form of spot interviews during the month of January 2020. The
analysis of the data collected was carried out using the Logit econometric model. The results show that the main determinants of household food
vulnerability to food insecurity in Bangui and its surroundings are the level of education, the size of the household, marital status, the case of
chronic illness, the income of the head of the household, gender of the head of household and food prices. However, those that have the highest
explanatory power on household vulnerability are the case of chronic diseases, food prices, the income of the head of household, marital status and
household size. On the other hand, the age and occupation of the head of household have no signicant inuence on the food vulnerability of
households. Thus, these results make it possible to make economic policy suggestions. This involves: (i) taking measures to improve the
purchasing power of the population by promoting income-generating activities; (ii) invest in education and vocational training in order to increase
the chance of self-employed workers in the informal sector to become entrepreneurs; (iii) developing a nutritional care program for people
suffering from chronic illnesses; (iv) promoting a good income redistribution policy within households; (v) strengthen social safety network in
order to support the livelihoods of poor households with the aim of promoting their access to food.
Computational Modelling of WDM-ROADM Node Implementations
Authors: Anchal Abhishek , Marom Dan M.
Published: February 2024

The value of colorless, directionless, and contentionless (CDC-)ROADM (reconfigurable optical add/drop multiplexer) nodes is strongly contested in the optical networking community. In this work, we compare known ROADM node designs incorporating different switching elements and account for their total nodal switching state support (in consideration of both channel routing and add/drop). This allows us to quantify the impact of directional/contentional accessibility constraints to add/drop transceivers. By considering the network node entity as a permutation network among its ingress/egress ports for all wavelength channels, which covers both through routing and add/drop assignments, we tabulate the node’s switching capacity, or total allowable connection states, per different ROADM architecture, hardware constraints, and finite number of add/drop transceivers. We further introduce the impact of idle wavelength channels on fiber links, as well as bidirectional routing assignments. Our switching capacity enumerations demonstrate that CDC-ROADM outperforms other designs, but parallel contentional aggregation hardware (partially contentional) and directional transceivers (permanently assigned to port directions) offer competitive performance under certain scenarios (at lower and higher number of deployed transceivers, or a combination of both). These findings suggest that design alternatives to the “difficult to implement” CDC-ROADM exist, with nearly equivalent switching capacity, and additional system considerations must be taken into account for ROADM design selection such as hardware availability, cost, impact of traffic churn, and disaster recovery with over-provisioned add/drop transceivers.
Prevalence and Psychosocial Risk Factors Associated with Depression in Older People in A Rural Community
Authors: González Daniel Antonio Muñoz , Caamal María Eugenia López , Figueroa María Concepción Ruiz de Chávez , Chan José Miguel Chin
Published: February 2024

Depression is a multifactorial disease that globally impacts all ages and sectors of the population. In this sense, it has become a public health problem, since it affects 280 million people in the world, according to information from the World Health Organization. Older adults represent 5.7% of the population that experiences this disease, with the moderate to severe stage being the one that most impacts their health, and, therefore, quality of life. For this reason, the objective of the research is to know the prevalence and psychosocial risk factors associated with depression in older people in the community of Santa Cruz, Hecelchakán, Campeche. The methodology used is with a quantitative approach because information was collected, based on the application of the Yesavage scale of geriatric depression, and the sociodemographic registry of 60 older adults of both sexes, in order to measure the percentage of prevalence through its respective epidemiological formula. Likewise, it is cross-sectional because it collected data in a single time: November 2022 – October 2023. Results: 46.7% experienced mild depression, 41.7% moderate depression and 11.6% severe depression. 55% of those interviewed were male and 45% female. The actual prevalence of depression is 100%. Likewise, the psychosocial risk factors identified were: the absence of recreational activities and social support networks, the economy, health services and family disintegration. Finally, it is necessary to design and implement socio-health intervention projects in the locality and with a socio-cultural perspective that impacts this age group, the family and from an intergenerational perspective, with the promotion of mental health being a priority goal in their execution.
Neuromeningeal Tuberculosis (TNM): Study of 24 Cases Covering Clinical, Paraclinical, Therapeutic and Progressive Aspects
Authors: Vieira Marcos , Aouni Yassine , Safsafi Youssef , Tounkara Samba , Reggad Ahmed , Elqatni Mohamed , Ennibi Khalid
Published: February 2024

This study aims to analyse the epidemiological, clinical, paraclinical, therapeutic and evolving aspects of neuromeningeal tuberculosis (TNM) through a retrospective study of 21 patients hospitalized between January 2019 and December 2023 in the infectious diseases department of the Rabat military hospital. The average age at diagnosis was 49.5 years, with a predominance in the age group of 20 to 40 years (47.61%). The average time to diagnosis was 25 days. Initial symptoms were generally general signs (100%), followed by headache (61.90%), vomiting (47.61%) and motor deficits (33.33%). All patients underwent lumbar puncture and brain CT scan. Anti-bacillary treatment and corticosteroid therapy were administered to all participants. The outcome was favorable in 61.90% of cases, fatal in 9.52%, and marked by neurological sequelae in 28.57%.
Address Form of Children in Communication (Through the Novel “Southen Forest Land”)
Authors: Lan Luu Thi , Hien Nguyen Thi
Published: February 2024

The article focuses on understanding children’s address forms through the novel “Southern Forest Land” from the following aspects: children's address terms to children and children’s address terms to adults. From the survey and classification results, we found that children's address in communication concentrates on two situations (family and community) with six thematic groups associated with two pairs of roles (upper-lower role pair and peer role pair Children's address terms to children have 2 forms of addressing and 5 forms of calling, while children's address terms to adults have 3 forms of addressing and 7 forms of calling. Analysis of the characteristics of address affirms that the language used by children is diverse, reflecting the entire spiritual life, innocence, and simplicity of children. It also reflects the honest, straightforward, warm, generous, and affectionate culture of the people in the Southern region.
Replacement of Total Abdominal Hysterectomy by TLH in a Patient with Previous Pelvic Surgery
Authors: Afroz Sharmin , Akhter Sumyia , Begum Amena , Begum Asma
Published: February 2024

Background: In a patient who had previous pelvic surgery, total laparoscopic hysterectomy (TLH) has well-established advantages over total abdominal hysterectomy. The hysterectomy is a common gynaecological operation. Although the vaginal route is preferred for hysterectomy, the best route for women who are not candidates for the vaginal approach is unknown. Hysterectomies are increasingly being performed laparoscopically as technology advances and experience grows. Objectives: The aim of this study is to evaluate the replacement of total abdominal hysterectomy by TLH in a patient with previous pelvic surgery. Method: This observational study was carried out on 60 women admitted in the Department of obstetrics and gynaecology, Labaid specialized Hospital, Dhaka, Bangladesh during the study period. The duration of the period was from July 2021 to June 2022. The data for this study about had been accumulated from patients sociodemographic & obstetrics information, physical examination and per-operative findings. Statistical evaluation of the results used to be got via the use of a window-based computer software program devised with Statistical Packages for Social Sciences (SPSS-24). Results: A total of 60 patients were included in final analysis. According to the study population's age distribution of the study population, it was observed that 15(25.0%) were in group 35-38, 23(38.33%) were in group 39-42, 16(26.66%) were in group 43-46 and 6(10.0%) were in group 47-50. according to patient demographics, it was observed that 44(73.33%) were Leiomyoma, 29(48.33%) were Bleeding, 3(5.0%) were Pelvic pressure, 19(31.66) were Pelvic pain and 15(0%) were size growth. Conclusion: TLH for endometrial pathology has few problems and is well tolerated by a restricted group of patients. For suitable patients, the benefits include decreased blood loss and a shorter hospital stay. TLH can be performed effectively despite previous abdominal surgery. Patients who had previous .......
Effective Management of Construction Project Team: Identifying Leadership Qualities and Responsibilities
Authors: Adham Tawfig Khidir Ibnouf , Sukkar Amr
Published: February 2024

Leadership within construction project teams is a critical aspect of effective project management, yet a comprehensive understanding of essential leadership qualities and responsibilities remains elusive in academic discourse. This research addresses this gap by identifying key leadership characteristics crucial for the efficient management of construction teams. The study objectives include exploring essential leadership characteristics and filling the gap in the leadership literature specific to the construction industry. This study employed a qualitative data collection and analysis approach involving in-depth interviews with nine seasoned professionals from diverse construction-related roles and organizations. The findings reveal that emotional intelligence and relationship building are paramount for creating a collaborative and innovative work environment. Empowerment and inclusivity foster team initiative and diversity, although caution is warranted to mitigate potential negative impacts on role stress and unethical behavior. Recognition and appreciation of team contributions contribute to morale and motivation, while continuous learning encourages adaptability and growth. Precise goal setting and efficient communication are foundational for focused and responsive team dynamics, while delegation and trust-building strategies promote collaboration and cohesion. Finally, prioritizing employee well-being ensures a positive and healthy work environment conducive to sustained engagement. The study contributes valuable insights into leadership characteristics vital for constructing teams' optimal functioning and management. The multifaceted nature of construction project management is highlighted, emphasizing the need for leaders to possess a diverse skill set to navigate the complexities of team dynamics in the construction industry. The findings provide actionable knowledge for practitioners and scholars, fostering a more holistic comprehension of effective ......
ANALISIS POSTUR KERJA PADA KONTRAKTOR DI PELABUHAN DAN PENGAPALAN UNTUK MEMINIMALISIR TERPAPAR MSD DENGAN METODE REBA DAN QEC (Studi Kasus: PT Pupuk Kalimantan Timur)
Authors: Mukti Yunas Prima
Published: February 2024

Postur kerja merupakan salah satu aspek penting yang harus diperhatikan oleh para pekerja, khususnya pada Tenaga Kerja Bongkar Muat. Kegiatan yang dilakukan saat bekerja secara berulang dapat menyebabkan penyakit akibat kerja, salah satunya Musculoskeletal Disorders (MSD). Koperasi Karya Kaltim merupakan tenaga kerja bongkar muat yang bekerja sama dengan PT. Pupuk Kalimantan Timur dalam memenuhi pekerjaan bongkar muat produk seperti pupuk urea dan NPK. Para pekerja bongkar muat melakukan pemindahan produk dari gudang ke kapal untuk di distribusikan kepada konsumen, proses yang dilakukan oleh pekerja adalah dengan mengangkat produk dengan berat 50 kg dari pallet yang disediakan secara berulang. Tujuan dari penelitian ini adalah melakukan analisis postur kerja pada koperasi tenaga kerja bongkar muat Karya Kaltim, sehingga dapat mengurangi risiko terpaparnya penyakit akibat kerja yang dapat mencelakai para pekerja. Analisis postur kerja menggunakan metode Rapid Entire Body Assessment dan Quick Exposure Checklist. Hasil penelitian ini berupa skor analisis postur kerja beserta perbaikan dalam upaya mengurangi risiko terpaparnya penyakit akibat kerja.
SISTEM INFORMASI PERSURATAN DI FAKULTAS SAINS DAN TEKNOLOGI UNIVERSITAS IBRAHIMY MENGGUNAKAN PHP DAN MYSQL
Authors: Ghofur Abd , Sya'diyah Halimatus , Lutfi Ahmad
Published: February 2024

Dalam pembuatan surat di Fakultas Sains dan Teknologi Universitas Ibrahimy masih dilakukan secara manual. Di Fakultas Sains dan Teknologi dibutuhkan sebuah Sistem Informasi Persuratan, hal ini sangat penting karena dengan adanya sistem tersebut dapat membantu kendala yang sedang dialami. Selain itu, dengan adanya sistem proses pencarian dan pembuatan surat tidak akan membutuhkan waktu yang lama begitu pula dengan semua surat yang sudah diarsip dalam penyimpanannya lebih teratur dan terorganisir serta dengan adanya sistem dapat menjaga surat dari kerusakan dan kehilangan. Begitu pula dapat memberikan akses yang mudah dalam pembuatan surat yang diperlukan.tujuan yang ingin dicapai dari penelitian ini adalah Membuat sistem pengarsipan yang baik sehingga proses pencarian kembali surat menjadi lebih cepat dari aspek waktu jika dibutuhkan pada suatu saat.Pada Sistem Informasi Persuratan di Fakultas Sains dan Teknologi Universitas Ibrahimy menggunakan jenis penelitian Field Research dan Library Research dengan metode pengumpulan data mulai dari Penelitian, Wawancara, dan Dokumentasi serta menggunakan metode pengembangan sistem Waterfall membuat sistem informasi persuratan yang mudah digunakan.
DETEKSI MALWARE MENGGUNAKAN MACHINE LEARNING DENGAN METODE ENSEMBLE
Authors: Matin Iik Muhamad Malik , Agustin Maria , Sugiarto Bambang , Asri Ai Nur
Published: February 2024

Serangan malware telah menjadi perhatian penting di di era digital ini. Malware dapat diartikan sebagai perangkat lunak yang digunakan untuk melakukan perusakan sistem, pencurian atau pengumpulan informasi, hingga mendapatkan akses terhadap suatu sistem. Machine learning merupakan sub area dari ilmu komputer yang mampu memberikan komputer kemampuan untuk belajar tanpa diprogram secara eksplisit. Pada penelitian ini akan mendeteksi malware windows menggunakan machine learning dengan metode ensemble. Model klasifikasi yang digunakan adalah Decision Tree, Random forest, Bagging, AdaBoost dan Hist Gradient Boosting. Penelitian ini menggunakan dataset malware berbasis windows. Hasil yang didapatkan menggunakan algoritma Hist Gradient Boosting lebih tinggi yaitu sebesar 96,9% dibandingkan dengan algoritma Decision tree sebesar 93,5% algoritma Random forest sebesar 94,9% algoritma Adaboost sebesar 87,8% dan algoritma Bagging sebesar 95,8%
REDUKSI WASTE UNTUK MENINGKATKAN NILAI OVERALL EQUIPMENT EFFECTIVENESS (OEE)
Authors: Supriyanto Hari
Published: February 2024

Aktifitas produksi merupakan aktifitas utama di dalam membentuk produk. Bila salah satu aktifitas mengalami kegagalam maka akan berpengaruh pada kapasitas produksi. Salah satu usaha yang dapat dilakukan adalah meningkatkan efisiensi dari seluruh sumber daya perusahaan yang berdampak pada peningkatan kapasitas poduksi. Permasalahan utama adalah bagaimana mengidentifikasi pemborosan yang mengakibatkan penurunan kualitas dan kapasitas produksi. Tujuannya adalah identifikasi waste yang paling berpengaruh, dan menentukan alternatif kebijakan perbaikan untuk meningkatkan efisiensi dan kapasitas produksiDiperoleh hasil bahwa nilai availability adalah 85%, performance adalah 89% danÂ Â  nilai quality 88%. sehingga nilai Overall Equipment Effectiveness (OEE) adalah 66.2%. Nilai ini memberI indikasi bahwa perlu diakukan improvement pada proses produksi. Metoda yang dipakai untuk menyelesaikan permasalahan adalah dengan konsep Lean Manufacturing. Konsep ini menelusuri permasalahan inefisiensi dengan mencari waste (pemborosan) di sepanjang value stream.Â  Dengan penelusuran root cause analisys (RCA) maka penyebab utama dari tiap kategori waste dapat ditemukan.Â  Alternatif terbaik adalah pelatihan untuk direct labor, penjadwalan maintenance pada alat potong dan pengadaan pelatihan untuk indirect labor. Terjadi kenaikan nilai OEE dengan menerapkan alternatif terbaik yaitu sebesar OEE = 75%Â Â Â
SISTEM PENDUKUNG KEPUTUSAN PEMILIHAN SISWA KELAS UNGGULAN BERBASIS WEB DENGAN METODE TOPSIS
Authors: Wulandari Fera Tri
Published: February 2024

Pemilihan siswa kelas unggul di MAN 1 Boyolali diharapkan dapat membantu bidang kurikulum untuk menentukan program kemajuan madrasah. Dalam pemilihan siswa kelas unggul diperlukan suatu sistem yang dapat merekomendasikan siswa yang berdasarkan kriteria penilaian sebagai siswa yang benar terpilih pada kelas unggul. Dimulai dari proses analisa dasar penentuan kelas unggul yaitu nilai tes yang dijadikan ukuran kemampuan akademik, nilai hafalan al quran, nilai prestasi yang dimiliki, nilai sikap dalam rapor smp. /mts dan rapor akademik dari smp/mts yang selanjutnya dijadikan kriteria penilaian. Nilai yang diperoleh setiap atribut berdasarkan kriteria yang telah ditentukan akan diolah menggunakan metode TOPSIS untuk mendapatkan peringkat 30 besar nilai terbaik yang dapat direkomendasikan pada kelas unggul. Hasilnya ditampilkan dalam diagram garis untuk mendukung pengambilan keputusan pemilihan siswa kelas unggul MAN 1 Boyolali.
OPTIMASI DETERMINASI TOTAL FLAVONOID DARI DAUN JATI (TECTONA GRANDIS L.F) MENGGUNAKAN ETANOL DAN ASETON
Authors: Khasanah Uswatun , Khasanah Uswatun
Published: February 2024

Jati merupakan tumbuhan yang umumnya berada diwilayah tropis. Daun jati memiliki kandungan fitokimia seperti flavonoid, alkaloid, tanin, napthaquinones dan antrakuinon yang dapat menghambat pertumbuhan bakteri atau sebagai antibakteri. Penelitian ini mempelajari proses isolasi senyawa flavonoid dari hasil fraksinasi daun jati. Fraksinasi ekstrak daun jati dilakukandengan metode maserasi dengan pelarut etanol dan aseton. Pengaruh jenis pelarut (etanol dan aseton), konsentrasi pelarut etanol (35, 45, 55, 65, 75, 85, 96%) dan aseton (40, 50, 60. 70, 80, 90, 100%), waktu maserasi (1-7 hari), dan suhu awal pelarut (25, 30, 35, 40, 45, 50Â°C) terhadap kadar flavonoid dipelajari. Hasil menujukan kadar flavonoid tertinggi diperoleh pada ekstraksi maserasi selama 1 hari menggunakan pelarut etanol 85% dengan suhu pelarut 25Â°C. Sedangkan, ekstraksi dengan pelarut aseton menunjukkan kadar flavonoid tertinggi dengan konsentrasi aseton 85% pada perlakuan selama 3 hari dan suhu pelarut 45Â°C. Isolasi senyawa flavonoid paling optimum dengan pelarut aseton karena senyawa flavonoid dalam daun jati memiliki kepolaran yang serupa dengan pelarut aseton.
SUBSTITUSI PATI BIJI NANGKA (ARTOCARPUS HETEROPHYLLUS) DALAM FORMULASI CANGKANG KAPSUL LUNAK YANG DIKOMBINASIKAN DENGAN KARAGENAN
Authors: Septina Ninuk Dina Luciani , Aliyatunnaim Nida Amalia , Ginting Diandra Fitry Angelin , Maharani Farikha
Published: February 2024

AbstrakKapsul sangat penting dalam pengemasan sediaan obat. Cangkang kapsul lunak komersial umumnya berasal dari gelatin babi. Salah satu alternatif pengganti gelatin dari bahan non hewani dapat diperoleh dari polisakarida seperti pati. Sumber pati salah satunya berasal dari biji nangka. Pembuatan cangkang kapsul lunak menggunakan metode percetakan dengan media petri dish. Tujuan dari riset ini adalah (i) mengetahui formulasi cangkang kapsul lunak terbaik dan (ii) mengetahui karakteristik cangkang kapsul lunak. Hasil formulasi terbaik diperoleh pada formulasi 1:1 5% (5 gram karagenan, 5 gram pati dan 5% gliserin) dengan lama waktu kelarutan dalam air 15.30 menit dan kelarutan dalam asam 21.04 menit.
Measurement Of Total Productive Maintenance (TPM) Using The Overall Equipment Effectiveness (OEE) Method On Fermentation Machinery At Pt. Indo Acidatama Tbk
Authors: Putra Muhammad Firnas Balisca , Zakaria Roni
Published: February 2024

Ethanol, or ethyl alcohol, has many applications in a variety of industries, including as a solvent, fuel, and in pharmaceuticals. Demand for ethanol in Indonesia is high, but domestic production is not sufficient, which prompted the establishment of PT. Indo Acidatama Tbk in 1986. This company produces ethanol from sugar cane molasses through a fermentation process using the yeast saccharomyces cerevisae strain Kyowa. The fermentation process requires good care to ensure optimal results and prevent machine failure. This research aims to measure the Overall Equipment Effectiveness (OEE) value of the fermentation machine at PT Indo Acidatama, identify the factors that influence the production performance of the fermentation machine, and determine the main causes of losses that affect the effectiveness of the fermentation machine. The research results show that the OEE value of the fermentation machine at PT Indo Acidatama in January 2023 is 85%, which is in accordance with JIP standards. The main causes of loss of machine effectiveness are breakdown losses (8.7%), reduced speed losses (5.9%), and rework losses (0.2%). To increase the effectiveness of fermentation machines, it is recommended to adjust process parameters, provide training to staff, and carry out regular data monitoring.
Analisa Kekuatan Chasis Belakang Pada Mobil Lintang Samudra Tahun 2022
Authors: Fu'ad Nur , Nugroho Agung
Published: February 2024

Chassis atau kerangka adalah sebuah struktur frame, dimana struktur itu harus kuat dari gaya tekan, gaya geser dan gaya tarik. Fungsi Chassis pada mobil adalah rangka internal yang menjadi dasar produksi objek yang kemudian disatukan dengan elemen lainnya seperti mesin, kemudi, body ataupun kelistrikan. Chassis juga berfungsi sebagai penopang berat kendaraan, berat pengemudi dan menjaga agar mobil tetap rigid dan kokoh sehingga tidak mengalami bending dan terjadi patah. Dalam konsep perancangan chassis perlu mengetahui apa yang dilakukan perbaikan terhadap perkembangan suatu produk, sehingga hasil yang diperoleh akan maksimal. Setelah memperhitungkan baik maupun buruknya dalam perencanaan perlu menentukan karakteristik produk Perancangan kekuatan pada chassis dengan menghitung Tegangan ,Regangan ,Modulus Elastisitas, Momen Inersia dan Safety Factor Tujuan penelitian ini untuk menganalisa kekuatan chassis bagian belakang mobil lintang samudra 2022 dengan analisa secara matematis dan simulasi. Hasil penelitian ini untuk mengomptimalkan perbandingan kekuatan chassis bagian belakang mobil lintang samudra 2022 dengan tahun 2021.
TRANSTORNO OBSESSIVO-COMPULSIVO (TOC) E NEUROIMAGEM
Authors: Cardozo Jhessyka Burgatti , Coelho Giovanna Nunes Vrech , França Weudson Cabral de , Macedo Jamilly Maria Monteiro , Fagundes Priscila Carine Leite , De Paulo Carlos Henrique Rodrigues , Kato Ana Beatriz Doufem , Calçada Marcela Nunes , Costa Junior Carlos augusto Leão , Freitas Edenizar Gomes de , Costa Lucas Bonna , Duarte Neto Jarbas Gomes , Moreira Henrique Correia , Braga Maurilio Camacho , Moyses Izabela C. Toledo Diniz , Moura Vanessa Maldonado de Holanda , Bessa Nathalia Sbampato Mol , Morais Júlia Rodna Gomes Paiva Arcanjo de , Paysano Maria Lúcia Brito de Araujo , Gouveia Pietro Brandão , Cruz Juliana Gomes , Cavalcante Rômulo Basílio Ferro Gomes , Coímbra Igor Bonifácio Andrade , Rapette Fiama Jéssica Francieli Cardoso , Laís Jaciara Costa Revil  , Carvalho Miriam Campos Soares de , Silva Manuela Sousa
Published: February 2024

As técnicas avançadas de neuroimagem têm desempenhado um papel fundamental na elucidação das alterações cerebrais no Transtorno obsessivo-compulsivo (TOC). Essas descobertas não só ampliam a compreensão da fisiopatologia do TOC, mas abrem caminho para o desenvolvimento de intervenções terapêuticas mais eficazes e personalizadas. À medida que são aprimoradas as habilidades em neuroimagem, pode-se esperar uma compreensão cada vez mais refinada das bases neurobiológicas dos transtornos psiquiátricos, como o TOC, oferecendo esperança e oportunidades para uma melhor qualidade de vida para aqueles que sofrem com essas condições. Este estudo teve como objetivo investigar as alterações cerebrais associadas ao TOC usando técnicas avançadas de neuroimagem. Diante disso, realizou-se uma revisão sistemática da literatura, utilizando as bases de dados Scielo, Lilacs e Medline. Após análise qualitativa dos resultados, concluiu-se que as técnicas avançadas de neuroimagem fornecem evidências objetivas das alterações cerebrais associadas ao Transtorno Obsessivo-Compulsivo (TOC), contribuindo para uma compreensão mais profunda das bases neurais do transtorno e destacando o papel crucial dessas técnicas na investigação e desenvolvimento de estratégias de diagnóstico e tratamento.
TO THE QUESTION OF FOREIGN LANGUAGE INCLUSIONS IN THE TEXTS OF ARTISTIC STYLE OF SPEECH BY M.I. TSVETAEVA
Authors: Олейникова О.Н.
Published: February 2024

Данная публикация посвящена вопросу функционирования в текстах художественного стиля речи М.И. Цветаевой иноязычных вкраплений из некоторых языков и их типологии. Иноязычные вкрапления представляют собой интереснейшее речевое явление, тем более в текстах не просто поэта, ставшего ныне классиком русской литературы, но и уникальной языковой личности. Цель статьи состоит в выявлении особенностей отбора и ввода М.И. Цветаевой иноязычных вкраплений в тексты, в определении их стилистического статуса, связанности использования вкраплений поэтом с культурной традицией, сформировавшейся в XIX веке. Иноязычные вкрапления проанализированы по соотношению с системами контактирующих языков. Выделены полные иноязычные вкрапления (не ассимилированные никаким образом и не включённые в синтаксические связи), часть которых представляет собой библионимы и эпиграфы. Обнаружены частичные вкрапления (имеющие морфологические показатели синтаксической связи с членами предложения или не имеющие таковой). Вкрапления в русской графике редки. Отсутствуют нулевые вкрапления и вкрапления, имитирующие ломаную речь иностранца. Произведен анализ иноязычных вкраплений с точки зрения национально-культурной специфики текста. Выделены вкрапления, связанные с нею и не связанные, а также вкрапления узуального характера. Использовался метод сплошной выборки исследуемого материала. Сделан вывод о связанности ввода в тексты М.И. Цветаевой иноязычных вкраплений с художественным замыслом поэта, со сложившейся культурной традицией их использования, с полученным Цветаевой классическим образованием, её полилингвизмом и фактами биографии. Отмечены индивидуальные особенности использования ею вкраплений. Сделана попытка объяснения ввода поэтом вкраплений в художественные тексты и выбора их типа и разряда.
ACOUSTIC IMAGES IN THE METAPHOR NOVEL BY M. BEYER "FLYING DOGS"
Authors: Воротникова А.Э. , Саратова М.В.
Published: February 2024

Статья посвящена интерпретации акустических образов в романе современного немецкого писателя М. Байера «Летучие собаки», обращенном к неновой, но по-прежнему актуальной проблематике фашистского прошлого и исторической памяти, индивидуальной и коллективной вины и покаяния. В фокусе исследовательского интереса – жанровая специфика байеровского произведения как романа-метафоры, соединяющего реалистический, конкретно-исторический, и обобщенно-образный планы повествования. Анализ метафор из акустической художественной концептосферы позволяет продемонстрировать механизм мгновенного и часто неожиданного сближения романных образов и объединения их в новую реальность более высокого идейно-эстетического уровня. Отмечается многообразие функций феномена звука, выступающего в качестве двигателя сюжетного развития и идейно-художественного центра произведения, задающего композицию образов главных героев и нарративную структуру романа, выявляющего мировоззренческие особенности личности протагониста – ученого Карнау – и этапы его духовной и морально-нравственной деградации. Использование звукообразов придает повествованию поливалентный и полифонический характер. Одним из важнейших художественных приемов в «Летучих собаках» является синестезия, проявляющаяся во влиянии акустических образов на хронотопическую организацию романа, а также в их корреляции с цветообразами. Пристальное внимание уделяется таким соотнесенным со звуком образам, как глухонемые, летучие собаки, эхо, пустота, технические средства. Особо рассматривается оппозиция голоса–молчания. Образ звука, будучи идейно-эстетическим первоэлементом, служит призмой, собирающей воедино многоаспектную картину жизни в нацистской Германии и высвечивающей ее скрытые идеологические основания, практикуемые в ней методы пропагандистского воздействия на индивидуальное и массовое сознание.
ENGLISH NEOLOGISMS WITH SUFFIX -ISM: SEMANTIC AND STYLISTIC POTENTIAL
Authors: Катермина В.В.
Published: February 2024

В статье рассматриваются неологизмы англоязычного дискурса с суффиксом -ism. Анализируется семантический план неологизмов, выявляются стилистические особенности данного лексического пласта. Подчеркивается, что возникновение нового является сущностным свойством любой системы, следствием ее развития, движения вперед, неотъемлемым признаком и свидетельством ее жизнеспособности. Появление новых слов в системе языка любого народа – яркий пример данной тенденции и подтверждение двух главных принципов языковой системы – ее динамизма и открытости. Основными методами исследования являются семантический и стилистический анализы, применяемые для выявления смысловых доминант английских неологизмов с суффиксом -ism, извлеченных из электронных лексикографических источников. Суффиксация обладает высочайшей продуктивностью в образовании новых слов. Хотя суффиксы не свободны синтаксически, они определенно обладают семантическим содержанием, грамматическим, словообразовательным и стилистическим значением. Большинство продуктивных суффиксов, образуя новые слова, придают им разнообразные эмоционально-экспрессивные оттенки и одновременно закрепляют их за той или иной сферой употребления. Основным значением суффикса -ism среди англоязычных неологизмов остается «научная доктрина, учение, направление». Анализ единиц позволил выделить такие дополнительные значения суффикса -ism, как «отклонение от нормы, исключение людей из общества на основании определенного признака», «поддержка социального или политического движения», «опыт, практика, деятельность». В процессе словообразования находят яркое отражение изменения в словарном составе языка, связанные с развитием общества. Динамика словообразовательной системы реализуется через ее потенциал – определенные словообразовательные возможности, предопределяющие те или иные тенденции языковой эволюции.
LIVED EXPERIENCES OF STUDENTS DURING THE TRANSITION FROM MODULAR TO IN-PERSON CLASS: ORAL RECITATION IN FOCUS
Authors: Shaika G. Gregorio  , Dr. Jeramie S. Pilayan
Published: February 2024

This phenomenological study aimed to investigate the experiences of senior high school students transitioning from modular to in-person learning in the new normal education setting. The research involved in-depth interviews and focus group discussions with Grade 12 students who had previously used modular learning. Participants, aged 18 or above, were purposively sampled from the Schools Division of City of Mati, having engaged in modular education during the academic years 2020–2021 and 2021–2022. Thematic analysis revealed five major themes related to the students experiences in transitioning, focusing on oral recitation. Another set of four major themes emerged regarding coping mechanisms, and additional themes depicted insights into learning approaches and classroom participation. The study recommends integrating more platforms associated with Speech Mastery Workshops to allow students to practice oral recitation in a supportive environment. Additionally, it advocates for teacher training to enhance educators understanding of emotions, active listening, and empathetic responses.
KEYWORDS: senior high school students, oral recitation, transition, in-person class qualitative research, phenomenological approach, thematic analysis, City of Mati
Making assessment a team sport: a qualitative study of facilitated group feedback in internal medicine residency
Authors: Braund Heather , Dalgarno Nancy , O'Dell Rachel , Taylor David R
Published: February 2024

Purpose: Competency-based medical education relies on feedback from workplace-based assessment (WBA) to direct learning. Unfortunately, WBAs often lack rich narrative feedback and show bias towards Medical Expert aspects of care. Building on research examining interactive assessment approaches, the Queen’s University Internal Medicine residency program introduced a facilitated, team-based assessment initiative (“Feedback Fridays”) in July 2017, aimed at improving holistic assessment of resident performance on the inpatient medicine teaching units. In this study, we aim to explore how Feedback Fridays contributed to formative assessment of Internal Medicine residents within our current model of competency-based training.
Method: A total of 53 residents participated in facilitated, biweekly group assessment sessions during the 2017 and 2018 academic year. Each session was a 30-minute facilitated assessment discussion done with one inpatient team, which included medical students, residents, and their supervising attending. Feedback from the discussion was collected, summarized, and documented in narrative form in electronic WBA forms by the program’s assessment officer for the residents. For research purposes, verbatim transcripts of feedback sessions were analyzed thematically.
Results: The researchers identified four major themes for feedback: communication, intra- and inter-personal awareness, leadership and teamwork, and learning opportunities. Although feedback related to a broad range of activities, it showed strong emphasis on competencies within the intrinsic CanMEDS roles. Additionally, a clear formative focus in the feedback was another important finding.
Conclusions: The introduction of facilitated team-based assessment in the Queen’s Internal Medicine program filled an important gap in WBA by providing learners with detailed feedback across all CanMEDS roles and by providing constructive recommendations for identified areas for improvement.
Unveiling the unborn: Advancing fetal health classification through machine learning
Authors: Mandala Sujith K.
Published: February 2024

Fetal health classification is a critical task in obstetrics, which enables early identification and management of potential health problems. However, it remains a challenging task due to data complexity and limited labeled samples. This research paper presents a novel machine-learning approach for fetal health classification, leveraging a LightGBM classifier trained on a comprehensive dataset. The proposed model achieves an impressive accuracy of 98.31% on a test set. The findings demonstrate machine learning can potentially enhance fetal health classification, offering a more objective and accurate assessment. Notably, the presented approach combines various features, such as fetal heart rate, uterine contractions, and maternal blood pressure, to provide a comprehensive evaluation. This methodology holds promise for improving early detection and treatment of fetal health issues, ensuring better outcomes for both mothers and babies. In addition to the high accuracy, the novelty of this approach lies in its comprehensive feature selection and assessment methodology. By incorporating multiple data points, this model offers a more holistic and reliable evaluation compared to traditional methods. This research has significant implications in the field of obstetrics, paving the way for advancements in early detection and intervention of fetal health concerns. Future work involves validating the model on a larger dataset and developing a clinical application. Ultimately, we anticipate that our research will revolutionize the assessment and management of fetal health, contributing to improved healthcare outcomes for expectant mothers and their fetuses.
Natural language processing in electronic health records: A review
Authors: Gurav Prachi
Published: February 2024

The two fundamental tasks that a physician performs during every interaction with a patient are reading and updating electronic health records (EHRs). Reading the records is necessary to gain better knowledge of a patient’s health status while updating the records is essential for creating a database for future information extraction. If a patient’s history consists of only a few records, manual reading is the best approach. However, this method may lead to overlooking important aspects of the patient’s health, which could be detrimental. Therefore, automation is required to extract important information. Natural language processing (NLP) facilitates information extraction and operates on seven different levels. In our review, we aimed to understand how NLP levels assist in extracting information. We examined articles published in PubMed and, after critical evaluation, selected 65 out of 382 identified articles that met the inclusion criteria for the final review. Among these, 47 articles were included in the final review. We found a higher number of articles on the lexical (7), semantic (30), and morphological (4) levels, while fewer articles focused on the phonetic (1), syntactic (2), discourse (2), and pragmatic (1) levels. This distribution underscores the current emphasis within the literature on the specific aspects of NLP. In conclusion, our review underscores the critical role played by NLP in extracting information from EHR, shedding light on the varied levels at which this technology operates.
Therapeutic potential of mesenchymal stem cells and their mechanisms of regeneration for cardiac diseases
Authors: Poomani Merlin Sobia , Radhakrishnan Varshini , James Senolin Bindhia , Muthan Krishnaveni , Subramanian Venkatesh
Published: February 2024

Ischemic heart disease remains a major contributor to mortality and disability despite significant advancements in traditional treatments. This threat underscores the need for exploring innovative cell-based therapies. The analysis of various stem and progenitor cells’ capacity to promote heart regeneration has led to encouraging outcomes in preclinical and clinical experiments. Mesenchymal stem cells (MSCs) have demonstrated the ability to contribute to heart regeneration through several pathways, including differentiation from the mesoderm lineage, immunomodulatory characteristics, and paracrine actions. In addition, their accessibility, maintenance, and capacity to replenish endogenous stem cell niches render them appropriate for cutting-edge research. This review outlines the robust mechanism underpinning MSC-based heart regeneration, presents the potential therapeutic uses of MSCs for ischemic heart disease, and highlights some preclinical findings.
Hypochloremia in heart failure: A new prognostic and therapeutic aspect of refractory heart failure
Authors: Raza Shafaat , Ditto Shahzeen Allah
Published: February 2024

Heart failure (HF) is one of the most common cardiovascular diseases, bearing a significant burden of morbidity, mortality, and disability. Low serum chloride (Cl) levels have been observed to play an important role in predicting mortality and planning management strategies for HF. This review aims to investigate the influence of hypochloremia on individuals suffering from HF and its correlation with various underlying pathophysiological mechanisms. We conducted a literature review of articles published in the past 10 years, employing specific keywords to identify relevant studies from databases such as PubMed, Google Scholar, EBSCO, and Biomed Central. There is a significant paucity of studies relevant to low serum Cl levels in patients with HF. We found that hypochloremia is commonly observed in HF cases, an often overlooked aspect in clinical setting, and is associated with poor outcomes. Substantial evidence supports the notion that hypochloremia can worsen HF, reduce the response to guideline-mediated therapies, and increase mortality. Hypochloremia activates numerous neurohormonal mechanisms, further worsening the cardiorenal circuit in HF. Furthermore, low Cl levels are associated with the development of diuretic resistance, making HF difficult to manage, particularly with loop diuretics. Studies reveal associations between hypochloremia and various kinases, with a particular emphasis on with-no-lysine kinases. These kinases, involved in regulating salt and water reabsorption, exacerbate the condition when Cl levels are low. Notably, a low serum Cl level is associated with high mortality in HF and worsens the condition. HF with hypochloremia poses challenges in treatment and should, therefore, be considered in management.