bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables S1-S4 from Downregulated miR329 and miR410 Promote the Proliferation and Invasion of Oral Squamous Cell Carcinoma by Targeting Wnt-7b
Authors: Shiah Shine-Gwo , Hsiao Jenn-Ren , Chang Wei-Min , Chen Ya-Wen , Jin Ying-Tai , Wong Tung-Yiu , Huang Jehn-Shyun , Tsai Sen-Tien , Hsu Yuan-Ming , Chou Sung-Tau , Yen Yi-Chen , Jiang Shih Sheng , Shieh Yi-Shing , Chang I-Shou , Hsiao Michael , Chang Jang-Yang
Published: April 2023

Supplementary Tables S1-S4. Supplementary Table S1: Clinicopathological characteristics of 40 pairs of OSCC specimens and their corresponding non-tumorous epithelia. Supplementary Table S2: A list of deregulated miRNA in 40 pairs of OSCC specimens and their corresponding non-tumorous epithelia. Supplementary Table S3: Characteristics of 83 OSCC patients for Wnt-7b IHC study. Supplementary Table S4: Top ten of enriched transcriptional factors in miRNA overexpression.
Supplementary Figures S1-S10 from Cellular Factors Promoting Resistance to Effective Treatment of Glioma with Oncolytic Myxoma Virus
Authors: Zemp Franz J. , McKenzie Brienne A. , Lun Xueqing , Reilly Karlyne M. , McFadden Grant , Yong V. Wee , Forsyth Peter A.
Published: April 2023

Immunophenotyping of the K1492 glioma microenvironment in response to sterile injury (S1); Immunophenotyping of the K1492 glioma microenvironment after Myxoma virus treatment (S2); Virus infected areas of K1492 tumours are accompanied by polymorphonuclear cell infiltration (S3); K1861 and Spontaneous NPcis gliomas in C57Bl/6 mice have significant microglia and/or GIM recruitment (S4); Non-tumour bearing CCR2-deficient animals are only slightly impaired in clearing MYXV (S5); CCR2-deficient mice have an exaggerated recruitment of NK and T cells to the K1492 glioma in response to Myxoma treatment (S6); Minocycline administration mimics CCR2-null viral clearance kinetics but does not result in a survival advantage (S7); K1492 tumours in IL2Rγ mice are significantly depleted of NK and T cell populations (S8); Non-tumour bearing IL2Rγ-deficient animals are impaired in clearing MYXV (S9); Single low-dose cyclophosphamide combined with Myxoma treatment did result in improved treatment efficacy or viral infection (S10).
Supplementary Figure Legends from CCR5 Receptor Antagonists Block Metastasis to Bone of v-Src Oncogene–Transformed Metastatic Prostate Cancer Cell Lines
Authors: Sicoli Daniela , Jiao Xuanmao , Ju Xiaoming , Velasco-Velazquez Marco , Ertel Adam , Addya Sankar , Li Zhiping , Andò Sebastiano , Fatatis Alessandro , Paudyal Bishnuhari , Cristofanilli Massimo , Thakur Mathew L. , Lisanti Michael P. , Pestell Richard G.
Published: April 2023

Legend for Supplementary Figures S1-S12.
Data Supplement from A Novel Wnt Regulatory Axis in Endometrioid Endometrial Cancer
Authors: Zhao Yu , Yang Yihua , Trovik Jone , Sun Kun , Zhou Liang , Jiang Peiyong , Lau Tat-San , Hoivik Erling A. , Salvesen Helga B. , Sun Hao , Wang Huating
Published: April 2023

Supplemental Figures S1-S6. Promoter CpG methylation of PCDH10 in EEC samples (S1); PCDH10 inhibits EEC cell proliferation and induces cell apoptosis (S2); Genome-wide analysis of PCDH10 induced transcriptomic changes by RNAseq (S3); PCDH10 inhibits MALAT1 transcription through Wnt/β-catenin signaling (S4); PCDH10 expression decreases nuclear β-catenin level in HEC1-B cells (S5); MALAT1 expression in EEC tumors (S6).
Data Supplement from IL4 Receptor ILR4α Regulates Metastatic Colonization by Mammary Tumors through Multiple Signaling Pathways
Authors: Venmar Katherine T. , Carter Kathy J. , Hwang Daniel G. , Dozier E. Ashley , Fingleton Barbara
Published: April 2023

Supplemental Figure 5: IL4Ra expression is associated with changes in immune infiltration
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: April 2023

Supplementary Table S1. Acute leukemia patient characteristics.
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: April 2023

Supplementary Table S2. Primer sequences for PCR.
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: April 2023

Supplementary Figure S1. Chemical structure of afatinib and cytotoxicity effect of afatinib on various cell lines that used in this study.
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: April 2023

Supplementary Figure S2. Representative flow cytometry dot plots of apoptosis analysis in SP cells under exposure to combination of afatinib with topotecan or mitoxantrone were presented.
Supplemental Methods, Figure Legends from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: April 2023

Supplemental Methods, Supplemental Figure legends Figure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Figure S7
Supplementary Figure 2 from Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H2O2 Generation
Authors: Rawal Malvika , Schroeder Samuel R. , Wagner Brett A. , Cushing Cameron M. , Welsh Jessemae L. , Button Anna M. , Du Juan , Sibenaller Zita A. , Buettner Garry R. , Cullen Joseph J.
Published: April 2023

PDF file - 43K, Supplementary Figure S2. A bolus of H2O2 decreases the plating efficiency of human pancreatic cancer cell lines.
Supplementary Figure 5 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: April 2023

PDF file - 71K, Luciferase assays the effect of Sp3 and Sp4 on miR-22 transcription regulation.
Data Supplement from AMPK Reverses the Mesenchymal Phenotype of Cancer Cells by Targeting the Akt–MDM2–Foxo3a Signaling Axis
Authors: Chou Chih-Chien , Lee Kuen-Haur , Lai I-Lu , Wang Dasheng , Mo Xiaokui , Kulp Samuel K. , Shapiro Charles L. , Chen Ching-Shih
Published: April 2023

Table S1
Supplementary Figure 3 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: April 2023

PDF file - 17K, Western blot assays the effect of Sp3 and Sp4 on CD147 protein expression.
Supplementary Figure Legends, Table Legends from The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation
Authors: Raha Debasish , Wilson Timothy R. , Peng Jing , Peterson David , Yue Peng , Evangelista Marie , Wilson Catherine , Merchant Mark , Settleman Jeff
Published: April 2023

PDF file - 76KB
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: April 2023

Supplementary Table S5. Supplementary data indicating no differences in histone modification intensity between luminal epithelial cells and myoepithelial cells in complex carcinomas.
Supplemental Tables 1 - 3, Figure 1 from High Serum Iron Is Associated with Increased Cancer Risk
Authors: Wen Chi Pang , Lee June Han , Tai Ya-Ping , Wen Christopher , Wu Shiuan Be , Tsai Min Kuang , Hsieh Dennis P.H. , Chiang Hung-Che , Hsiung Chao Agnes , Hsu Chung Y. , Wu Xifeng
Published: April 2023

Supplemental Table 1. Hazard ratios for cancer incidence for different serum iron levels by smoking status. Supplemental Table 2. Cancer mortality risk for different serum iron levels Supplemental Table 3. Comparison of results of first and second test of serum iron. Supplemental Figure 1. J-shaped relationship between serum iron and cancer risk.
Supplementary Figures 1 - 6 from Mycoplasma Hyorhinis Infection Promotes NF-κB–Dependent Migration of Gastric Cancer Cells
Authors: Duan Hongying , Chen Ling , Qu Like , Yang Hua , Song Sonya Wei , Han Yong , Ye Meihua , Chen Wanyuan , He Xianglei , Shou Chengchao
Published: April 2023

Figure S1. Expression of p37 in gastric cancer tissues. Figure S2. p37 mediates M. hyorhinis infection. Figure S3. Alignment of N-terminal of p37 with proteins from other mycoplasma species. Figure S4. ANXA2 is essential for M. hyorhinis and p37 binding to cells. Figure S5. M. hyorhinis regulates ANXA2 localization in an EGFR-dependent manner. Figure S6. Gene Ontology (GO) analysis of genechip results indicate the activation of NF-kB signaling.
Supplementary Table 3 from Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties
Authors: Ostenfeld Marie Stampe , Jeppesen Dennis K. , Laurberg Jens R. , Boysen Anders T. , Bramsen Jesper B. , Primdal-Bengtson Bjarke , Hendrix An , Lamy Philippe , Dagnaes-Hansen Frederik , Rasmussen Mads H. , Bui Khan H. , Fristrup Niels , Christensen Erik I. , Nordentoft Iver , Morth Jens P. , Jensen Jørgen B. , Pedersen Jakob S. , Beck Martin , Theodorescu Dan , Borre Michael , Howard Kenneth A. , Dyrskjøt Lars , Ørntoft Torben Falck
Published: April 2023

Lists of A)Quantitative mass spectrometry results of RNA-binding proteins in exosomes, B) Selected miRNAs for further analysis, and C) Downregulated mRNA transcripts (selected) upon RAB27B knockdown.
Supplementary Figure 2 from Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties
Authors: Ostenfeld Marie Stampe , Jeppesen Dennis K. , Laurberg Jens R. , Boysen Anders T. , Bramsen Jesper B. , Primdal-Bengtson Bjarke , Hendrix An , Lamy Philippe , Dagnaes-Hansen Frederik , Rasmussen Mads H. , Bui Khan H. , Fristrup Niels , Christensen Erik I. , Nordentoft Iver , Morth Jens P. , Jensen Jørgen B. , Pedersen Jakob S. , Beck Martin , Theodorescu Dan , Borre Michael , Howard Kenneth A. , Dyrskjøt Lars , Ørntoft Torben Falck
Published: April 2023

Characterization of cells upon miRNA overexpression and knockdown.
Supplementary Figures S1-S6, Table S1-S2, and Materials and Methods from ISG15 Is a Critical Microenvironmental Factor for Pancreatic Cancer Stem Cells
Authors: Sainz Bruno , Martín Beatriz , Tatari Marianthi , Heeschen Christopher , Guerra Susana
Published: April 2023

Supplementary Figures S1-S6, Table S1-S2, and Materials and Methods. Figure S1 shows the distribution of macrophages and ISG15 expression in tissue from patient PDAC tumors, analyzed by IHC, and the expression of the CSC cell surface marker CD133 on PDAC cells cultured as adherent monolayers or as spheres. Figure S2 shows the growth of PDAC cells in vivo alone or with polarized human macrophages. Figure S3-S5 is a comprehensive IHC or IF analysis of ISG15 expression in multiple PDAC, breast and prostate cancer patient tumors. Figure S6 shows the migratory capacity of murine PDAC CSCs primed with control media or CM from M2-polarized ISG15+/+ or ISG15-/- murine macrophages. Table S1 lists the antibodies used in this study. Table S2 lists the sequences of the primers used for RTqPCR analysis.
Supplementary Table 1 - 9 and Figures 1 - 14 from Quantitative Optical Imaging of Primary Tumor Organoid Metabolism Predicts Drug Response in Breast Cancer
Authors: Walsh Alex J. , Cook Rebecca S. , Sanders Melinda E. , Aurisicchio Luigi , Ciliberto Gennaro , Arteaga Carlos L. , Skala Melissa C.
Published: April 2023

Supplementary Figure 1: OMI endpoints of organoids derived from a trastuzumabresponsive xenograft tumor. Supplementary Figure 2: Population modeling identifies heterogeneous drug responses of BT474 cells. Supplementary Figure 3: OMI endpoints of organoids derived from a trastuzumab-resistant xenograft tumor. Supplementary Figure 4: Population modeling identifies heterogeneous drug responses of HR6 cells. Supplementary Figure 5: Population modeling identifies heterogeneous drug responses of organoids from patient sample #1 (ER+/HER2-). Supplementary Figure 6: OMI endpoints of organoids derived from a ER+ primary tumor. Supplementary Figure 7: Population modeling identifies heterogeneous drug responses of organoids from patient sample #2 (ER+/HER2-). Supplementary Figure 8: OMI endpoints of organoids derived from a second ER+ primary tumor. Supplementary Figure 9: Population modeling identifies heterogeneous drug responses of organoids from patient sample #3 (ER+/HER2-). Supplementary Figure 10: Population modeling identifies heterogeneous drug responses of organoids from patient sample #4 (ER+/HER2-). Supplementary Figure 11: OMI endpoints of organoids derived from a third ER+ primary tumor. Supplementary Figure 12: OMI endpoints of organoids derived from a fourth ER+ primary tumor. Supplementary Figure 13: OMI endpoints of organoids derived from a HER2+ primary tumor. Supplementary Figure 14: OMI endpoints of organoids derived from a TNBC primary tumor. Supplementary Table 1: NADH and FAD lifetime component values of BT474-xenograft derived organoids. Supplementary Table 2: NADH and FAD lifetime component values. Supplementary Table 3: Grade, proliferation rate, estrogen receptor expression, progesterone receptor expression, and HER2 receptor. Supplementary Table 4: NADH and FAD lifetime component values Supplementary Table 5: NADH and FAD lifetime component values of organoids. Supplementary Table 6: NADH and FAD lifetime component values. Supplementary Table 7: NADH and FAD lifetime component values of organoids derived from a fourth ER+ primary tumor. Supplementary Table 8: NADH and FAD lifetime component values of organoids derived from a HER2+ primary tumor. Supplementary Table 9: NADH and FAD lifetime component values of organoids derived from a TNBC primary tumor.
Supplementary Table S2 from PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Authors: Yao Ruosi , Jiang Hao , Ma Yuhui , Wang Liping , Wang Lin , Du Juan , Hou Pingfu , Gao Yanyan , Zhao Li , Wang Guannan , Zhang Yu , Liu Dong-Xu , Huang Baiqu , Lu Jun
Published: April 2023

Expression of PRMT7 in clinical breast carcinoma samples
Supplementary Figure S2 from BET Protein Inhibitor JQ1 Attenuates Myc-Amplified MCC Tumor Growth In Vivo
Authors: Shao Qiang , Kannan Aarthi , Lin Zhenyu , Stack Brendan C. , Suen James Y. , Gao Ling
Published: April 2023

Supplementary Figure S2. JQ1 exerts no effect on apoptosis in both MCC-3 and MCC-5 cells.
Supplementary Table S1 from PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Authors: Yao Ruosi , Jiang Hao , Ma Yuhui , Wang Liping , Wang Lin , Du Juan , Hou Pingfu , Gao Yanyan , Zhao Li , Wang Guannan , Zhang Yu , Liu Dong-Xu , Huang Baiqu , Lu Jun
Published: April 2023

Expression of PRMT7 in normal breast tissues and breast carcinoma
Supplementary Figure S1 from BET Protein Inhibitor JQ1 Attenuates Myc-Amplified MCC Tumor Growth In Vivo
Authors: Shao Qiang , Kannan Aarthi , Lin Zhenyu , Stack Brendan C. , Suen James Y. , Gao Ling
Published: April 2023

Supplementary Figure S1. MCC cell morphology.
Supplementary Materials from PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Authors: Yao Ruosi , Jiang Hao , Ma Yuhui , Wang Liping , Wang Lin , Du Juan , Hou Pingfu , Gao Yanyan , Zhao Li , Wang Guannan , Zhang Yu , Liu Dong-Xu , Huang Baiqu , Lu Jun
Published: April 2023

supplementary materials and supplementary figure legends
Supplementary Figure S8 from PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Authors: Yao Ruosi , Jiang Hao , Ma Yuhui , Wang Liping , Wang Lin , Du Juan , Hou Pingfu , Gao Yanyan , Zhao Li , Wang Guannan , Zhang Yu , Liu Dong-Xu , Huang Baiqu , Lu Jun
Published: April 2023

Effect of PRMT7 on tumor cell growth.
Data Supplement from Hsp70–Bag3 Interactions Regulate Cancer-Related Signaling Networks
Authors: Colvin Teresa A. , Gabai Vladimir L. , Gong Jianlin , Calderwood Stuart K. , Li Hu , Gummuluru Suryaram , Matchuk Olga N. , Smirnova Svetlana G. , Orlova Nina V. , Zamulaeva Irina A. , Garcia-Marcos Mikel , Li Xiaokai , Young Z.T. , Rauch Jennifer N. , Gestwicki Jason E. , Takayama Shinichi , Sherman Michael Y.
Published: April 2023

Supplemental Figure S3. Dose dependent effect of YM-1 signaling pathways.
Supplementary Figure S4 from PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Authors: Yao Ruosi , Jiang Hao , Ma Yuhui , Wang Liping , Wang Lin , Du Juan , Hou Pingfu , Gao Yanyan , Zhao Li , Wang Guannan , Zhang Yu , Liu Dong-Xu , Huang Baiqu , Lu Jun
Published: April 2023

Effect of PRMT7 on MMP protein expressions and cell proliferation.
Data Supplement from Hsp70–Bag3 Interactions Regulate Cancer-Related Signaling Networks
Authors: Colvin Teresa A. , Gabai Vladimir L. , Gong Jianlin , Calderwood Stuart K. , Li Hu , Gummuluru Suryaram , Matchuk Olga N. , Smirnova Svetlana G. , Orlova Nina V. , Zamulaeva Irina A. , Garcia-Marcos Mikel , Li Xiaokai , Young Z.T. , Rauch Jennifer N. , Gestwicki Jason E. , Takayama Shinichi , Sherman Michael Y.
Published: April 2023

Legend for Supplemental Figures S1-S4.
Supplementary Figure S2 from PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Authors: Yao Ruosi , Jiang Hao , Ma Yuhui , Wang Liping , Wang Lin , Du Juan , Hou Pingfu , Gao Yanyan , Zhao Li , Wang Guannan , Zhang Yu , Liu Dong-Xu , Huang Baiqu , Lu Jun
Published: April 2023

PRMT7 induced an EMT program in other cell lines.
Data Supplement from NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis
Authors: Weaver Kelly L. , Alves-Guerra Marie-Clotilde , Jin Ke , Wang Zhiqiang , Han Xiaoqing , Ranganathan Prathibha , Zhu Xiaoxia , DaSilva Thiago , Liu Wei , Ratti Francesca , Demarest Renee M. , Tzimas Cristos , Rice Meghan , Carpio Rodrigo Vasquez-Del , Dahmane Nadia , Robbins David J. , Capobianco Anthony J.
Published: April 2023

Supplemental Methods
Data Supplement from NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis
Authors: Weaver Kelly L. , Alves-Guerra Marie-Clotilde , Jin Ke , Wang Zhiqiang , Han Xiaoqing , Ranganathan Prathibha , Zhu Xiaoxia , DaSilva Thiago , Liu Wei , Ratti Francesca , Demarest Renee M. , Tzimas Cristos , Rice Meghan , Carpio Rodrigo Vasquez-Del , Dahmane Nadia , Robbins David J. , Capobianco Anthony J.
Published: April 2023

Supplemental Figure S1 legend
Supplemental Figures S1-4, Tables S1-2, Methods and Materials from SA-4-1BBL and Monophosphoryl Lipid A Constitute an Efficacious Combination Adjuvant for Cancer Vaccines
Authors: Srivastava Abhishek K. , Dinc Gunes , Sharma Rajesh K. , Yolcu Esma S. , Zhao Hong , Shirwan Haval
Published: April 2023

Supplemental Figures S1-4, Tables S1-2, Methods and Materials. Figure S1. Tumor growth kinetics of individual mice subjected to various vaccinations. Figure S2. Absolute number of E749-57 peptide-specific CD8+ T cells expressing polyfunctional cytokines. Figure S3. SA-4-1BBL/MPL adjuvant system induced CD8+ T cell effector memory response. Figure S4. Therapeutic efficacy of two vaccinations of SA-4-1BBL/MPL in 3LL lung metastasis model. Table S1. SA-4-1BBL/MPL vaccine associated toxicity profile on various immune cells. Table S2. Effect of SA-4-1BBL/MPL vaccine on DCs.
Supplementary Table S2 from Oncogenic Properties of a Spermatogenic Meiotic Variant of Fer Kinase Expressed in Somatic Cells
Authors: Yaffe Etai , Hikri Elad , Elkis Yoav , Cohen Ortal , Segal Ariela , Makovski Adar , Varvak Alexander , Shpungin Sally , Nir Uri
Published: April 2023

Supplementary Table S2: summarizing tumor progression in immuno-compromised mice, up to 6 weeks after being subcutaneously injected with 4X106 NIH3T3-MTS- MycFerT, NIH3T3-MycFerT or NIH3T3-pIRES cells.
Supplementary Figure 8 from Flotillin-1 Regulates Oncogenic Signaling in Neuroblastoma Cells by Regulating ALK Membrane Association
Authors: Tomiyama Arata , Uekita Takamasa , Kamata Reiko , Sasaki Kazuki , Takita Junko , Ohira Miki , Nakagawara Akira , Kitanaka Chifumi , Mori Kentaro , Yamaguchi Hideki , Sakai Ryuichi
Published: April 2023

PDF file - 88KB, Supplementary Figure S8. Schematic overview of results. Cell surface expression of wild-type ALK, and probably some ALK mutants that have high affinity to FLOT1, is downregulated by FLOT-mediated endocytosis and subsequent degradation at lysosomes.
Supplementary Figure 7 from Flotillin-1 Regulates Oncogenic Signaling in Neuroblastoma Cells by Regulating ALK Membrane Association
Authors: Tomiyama Arata , Uekita Takamasa , Kamata Reiko , Sasaki Kazuki , Takita Junko , Ohira Miki , Nakagawara Akira , Kitanaka Chifumi , Mori Kentaro , Yamaguchi Hideki , Sakai Ryuichi
Published: April 2023

PDF file - 474KB, Supplementary Figure S7. FLOT1 regulates migration and resistance to CDDP-induced cell death of neuroblastoma cells expressing ALK mutants.
Supplementary Figure S1 from Oncogenic Properties of a Spermatogenic Meiotic Variant of Fer Kinase Expressed in Somatic Cells
Authors: Yaffe Etai , Hikri Elad , Elkis Yoav , Cohen Ortal , Segal Ariela , Makovski Adar , Varvak Alexander , Shpungin Sally , Nir Uri
Published: April 2023

Supplementary Figure S1: shows the induction of cellular ROS levels upon the down-regulation of Fer or FerT using different siRNA's.
Supplementary Figure 5 from Flotillin-1 Regulates Oncogenic Signaling in Neuroblastoma Cells by Regulating ALK Membrane Association
Authors: Tomiyama Arata , Uekita Takamasa , Kamata Reiko , Sasaki Kazuki , Takita Junko , Ohira Miki , Nakagawara Akira , Kitanaka Chifumi , Mori Kentaro , Yamaguchi Hideki , Sakai Ryuichi
Published: April 2023

PDF file - 363KB, Supplementary Figure S5. FLOT1 downregulates malignant phenotypes of neuroblastoma cells.
Supplementary Figures 1 - 4 , Table 1 from Notch Signaling Drives Stemness and Tumorigenicity of Esophageal Adenocarcinoma
Authors: Wang Zhiqiang , Da Silva Thiago G. , Jin Ke , Han Xiaoqing , Ranganathan Prathibha , Zhu Xiaoxia , Sanchez-Mejias Avencia , Bai Feng , Li Bin , Fei Dennis Liang , Weaver Kelly , Carpio Rodrigo Vasquez-Del , Moscowitz Anna E. , Koshenkov Vadim P. , Sanchez Lilly , Sparling Lynne , Pei Xin-Hai , Franceschi Dido , Ribeiro Afonso , Robbins David J. , Livingstone Alan S. , Capobianco Anthony J.
Published: April 2023

Figure S1 EAC has ligand dependent activation of Notch. Figure S2 Activations of Notch were elevated in esophageal adenocarcinoma cell lines. Figure S3 Activation of Notch signaling promotes proliferation of EAC cells. Figure S4 EAC derived tumor spheres display characteristics of cancer stem cells. Table S1 Active NOTCH signaling is associated with poor prognosis in EAC.
Supplementary Figure 2 from Flotillin-1 Regulates Oncogenic Signaling in Neuroblastoma Cells by Regulating ALK Membrane Association
Authors: Tomiyama Arata , Uekita Takamasa , Kamata Reiko , Sasaki Kazuki , Takita Junko , Ohira Miki , Nakagawara Akira , Kitanaka Chifumi , Mori Kentaro , Yamaguchi Hideki , Sakai Ryuichi
Published: April 2023

PDF file - 109KB, Supplementary Figure S2. Expression of FLOT1 and ALK in selected human neuroblastoma samples.
Supplementary Figure 1 from Flotillin-1 Regulates Oncogenic Signaling in Neuroblastoma Cells by Regulating ALK Membrane Association
Authors: Tomiyama Arata , Uekita Takamasa , Kamata Reiko , Sasaki Kazuki , Takita Junko , Ohira Miki , Nakagawara Akira , Kitanaka Chifumi , Mori Kentaro , Yamaguchi Hideki , Sakai Ryuichi
Published: April 2023

PDF file - 326KB, Supplementary Figure S1. Schematic of two-step immunoaffinity purification of tyrosine-phosphorylated proteins associated with ALK.
Supplementary Figure S4 from Efficacy of CAR T-cell Therapy in Large Tumors Relies upon Stromal Targeting by IFNγ
Authors: Textor Ana , Listopad Joanna J. , Wührmann Lara Le , Perez Cynthia , Kruschinski Anna , Chmielewski Markus , Abken Hinrich , Blankenstein Thomas , Charo Jehad
Published: April 2023

9-28-ζ-CAR-Ts accumulate at the tumor site
Supplementary figure and table legends from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary figure and Table Legends. Legends to supplementary tables and figures
Supplementary Figure S3 from Efficacy of CAR T-cell Therapy in Large Tumors Relies upon Stromal Targeting by IFNγ
Authors: Textor Ana , Listopad Joanna J. , Wührmann Lara Le , Perez Cynthia , Kruschinski Anna , Chmielewski Markus , Abken Hinrich , Blankenstein Thomas , Charo Jehad
Published: April 2023

Mice treated with ζ-CAR-Ts have a slight increase in total body signal when compared to mock treated control mice but less than 9-28-ζ-CAR-T
Supplementary Table S4 from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Table S4. Differentially expressed genes in E2-treated MCF7 cells following siRIP140.
Supplementary Figure S1 from Efficacy of CAR T-cell Therapy in Large Tumors Relies upon Stromal Targeting by IFNγ
Authors: Textor Ana , Listopad Joanna J. , Wührmann Lara Le , Perez Cynthia , Kruschinski Anna , Chmielewski Markus , Abken Hinrich , Blankenstein Thomas , Charo Jehad
Published: April 2023

Schematic representation of species-specific molecular interactions in models of CAR-mediated tumor rejection
Data Supplement from TLR9 Is Critical for Glioma Stem Cell Maintenance and Targeting
Authors: Herrmann Andreas , Cherryholmes Gregory , Schroeder Anne , Phallen Jillian , Alizadeh Darya , Xin Hong , Wang Tianyi , Lee Heehyoung , Lahtz Christoph , Swiderski Piotr , Armstrong Brian , Kowolik Claudia , Gallia Gary L. , Lim Michael , Brown Christine , Badie Behnam , Forman Stephen , Kortylewski Marcin , Jove Richard , Yu Hua
Published: April 2023

Figure S1. Increased TLR9 expression in induced glioma spheres. Figure S2. TLR9 and STAT3 form a feed-forward loop in GSCs. Figure S3. Stat3 silencing by local CpG-Stat3siRNA delivery inhibits tumor growth. Figure S4. Stat3 silencing by local CpG-Stat3siRNA delivery inhibits GSCs. Figure S5. Targeting Brain tumors systemically with CpG-siRNA reaches the tumor site.
Supplementary Methods from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Methods Section
Supplementary Figures, Table, and Materials and Methods from CD98hc (SLC3A2) Loss Protects Against Ras-Driven Tumorigenesis by Modulating Integrin-Mediated Mechanotransduction
Authors: Estrach Soline , Lee Sin-Ae , Boulter Etienne , Pisano Sabrina , Errante Aurélia , Tissot Floriane S. , Cailleteau Laurence , Pons Catherine , Ginsberg Mark H. , Féral Chloé C.
Published: April 2023

Supplementary Figures, Table, and Materials and Methods. Supplementary Figures S1-4. S1: Skin sections of control and 4OHT treated mice. S2: Immunohistochemical analysis of murine back skin sections from vehicle- (Ctrl) and 4OHT-treated mice with antibodies against P-Cofilin, and IgG control. S3: Quantitative RT-PCR of YAP/TAZ signaling markers. S4: CD98hc-deficient keratinocytes (GFP positive) reconstituted with different chimeras were seeded on 50kPa stiffness collagen-coated hydrogels for 48 hours. Supplemental Table 1. Set of qRT-PCR specific primers Sup Materials and Methods
Supplementary Figure S6 from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Figure S6. Additional patient subgroup analyses from hierarchical clustering analyses.
Supplementary Information from miR326 Maturation Is Crucial for VEGF-C–Driven Cortactin Expression and Esophageal Cancer Progression
Authors: Hong Chih-Chen , Chen Pai-Sheng , Chiou Jean , Chiu Ching-Feng , Yang Ching-Yao , Hsiao Michael , Chang Yi-Wen , Yu Yang-Hao , Hung Mien-Chie , Hsu Nai-Wen , Shiah Shine-Gwo , Hsu Nan-Yung , Su Jen-Liang
Published: April 2023

Supplementary Information
Data Supplement from IDH1 R132H Mutation Generates a Distinct Phospholipid Metabolite Profile in Glioma
Authors: Esmaeili Morteza , Hamans Bob C. , Navis Anna C. , van Horssen Remco , Bathen Tone F. , Gribbestad Ingrid S. , Leenders William P. , Heerschap Arend
Published: April 2023

Supplementary Materials and Methods, Figure Legends.
Supplementary Video 2 from NGF Blockade at Early Times during Bone Cancer Development Attenuates Bone Destruction and Increases Limb Use
Authors: McCaffrey Gwen , Thompson Michelle L. , Majuta Lisa , Fealk Michelle N. , Chartier Stephane , Longo Geraldine , Mantyh Patrick W.
Published: April 2023

This film depicts the spontaneous nocifensive behavior of a mouse at Day 17 post-cancer cell injection. Throughout the film there are several visual cues that are indicative of nocifensive behavior. The pronounced changes in behavior and movements of the hind limbs when compared to naÃƒÂ¯ve animals allow the observer to precisely measure the time spent in nocifensive behavior. Seconds 1-6: Full guarding behavior is present in the left hind limb: it is fully lifted above the wire mesh with the toes held together, and the foot pad appears darkened as the mouse is holding the limb close to its body. In contrast, the non-tumor-bearing limb bears weight on the wire floor. The right foot pad skin has variation in its brightness and spread out toes that firmly rest on the wire cage floor during each step. Seconds 9-11: Reduced weight-bearing behavior is seen: the toes of the left foot poke through the wire floor, indicating that the foot pad is not resting on the floor and the mouse is not bearing its full weight on this limb. Seconds 11-14: Additional display of reduced weight-bearing behavior: the left leg and foot are cupped and turned down to the wire with toes held together. Seconds 15-17: Sporadic hopping: the left leg is lifted and held at an angle above the wire with the foot pad cupped and turned/rotated to face the midline of the body during each step as it hops. Seconds 17-21: Reduced weight-bearing behavior is displayed: the left foot is held above the wire and it appears dark with toes held together. Seconds 21-31: The toes of the left foot are spread out and a range of brightness appears on the bottom of the foot because it is bearing weight on the wire floor; time spent in this position would not be counted as nocifensive behavior. Seconds 33-49: Full guarding behavior is displayed. Seconds 49-53: Reduced weight-bearing behavior is displayed. Seconds 55-60: Sporadic hopping and reduced weight-bearing. Note: This video does not include footage of a mouse tending to the affected limb or grooming its haunches. Tending to the affected limb is abnormal grooming/licking behavior directed solely to the affected foot and limb. Grooming of the haunches of the affected limb is not counted as nocifensive behavior.
Supplementary Figure 4 from Germline Mutation of Bap1 Accelerates Development of Asbestos-Induced Malignant Mesothelioma
Authors: Xu Jinfei , Kadariya Yuwaraj , Cheung Mitchell , Pei Jianming , Talarchek Jacqueline , Sementino Eleonora , Tan Yinfei , Menges Craig W. , Cai Kathy Q. , Litwin Samuel , Peng Hongzhuang , Karar Jayashree , Rauscher Frank J. , Testa Joseph R.
Published: April 2023

PDF file - 415K, Supplementary Figure 4. A and B, strong staining for the MM marker mesothelin seen in tumor tissues from both WT and Bap1+/- mice. C, Bap1 staining in MM tissue from WT mouse. MM, malignant mesothelioma; NI, normal intestinal mucosa, both stained positively for Bap1. D, lack of staining for Bap1 in MM from Bap1+/- mouse.
Supplementary Figure 1 from Germline Mutation of Bap1 Accelerates Development of Asbestos-Induced Malignant Mesothelioma
Authors: Xu Jinfei , Kadariya Yuwaraj , Cheung Mitchell , Pei Jianming , Talarchek Jacqueline , Sementino Eleonora , Tan Yinfei , Menges Craig W. , Cai Kathy Q. , Litwin Samuel , Peng Hongzhuang , Karar Jayashree , Rauscher Frank J. , Testa Joseph R.
Published: April 2023

PDF file - 472K, Supplementary Figure 1. A, histogram depicting fiber length distribution in microns. B, dot blot illustrating fiber length and width distributions. Red line depicts mean length of fibers (6.78 μm). Mean fiber width was 0.42 microm. C and D, SEM images of fiber preparations at magnifications x2,500 and x5,000, respectively. Size bars indicate 10 μm and 1 μm in corresponding panels C and D.
Supplemental Materials and Methods, Supplemental Video Legends from NGF Blockade at Early Times during Bone Cancer Development Attenuates Bone Destruction and Increases Limb Use
Authors: McCaffrey Gwen , Thompson Michelle L. , Majuta Lisa , Fealk Michelle N. , Chartier Stephane , Longo Geraldine , Mantyh Patrick W.
Published: April 2023

This file provides supplemental materials and methods, supplemental video legends, and supplemental material references.
Supplementary Tables 1 - 7 and Figures 1 - 3 from Genetic Evidence of a Precisely Tuned Dysregulation in the Hypoxia Signaling Pathway during Oncogenesis
Authors: Couvé Sophie , Ladroue Charline , Laine Elodie , Mahtouk Karène , Guégan Justine , Gad Sophie , Le Jeune Hélène , Le Gentil Marion , Nuel Gregory , Kim William Y. , Lecomte Bernard , Pagès Jean-Christophe , Collin Christine , Lasne Françoise , Benusiglio Patrick R. , Bressac-de Paillerets Brigitte , Feunteun Jean , Lazar Vladimir , Gimenez-Roqueplo Anne-Paule , Mazure Nathalie M. , Dessen Philippe , Tchertanov Luba , Mole David R. , Kaelin William , Ratcliffe Peter , Richard Stéphane , Gardie Betty
Published: April 2023

Table S1: Phenotypes associated with single R161Q and R200W VHL germline mutations are different from the phenotype associated with the combined mutations. Table S2: VHL mutations associated with polycythemia are different from the VHL mutations involved in severe von Hippel-Lindau disease. Table S3: Members of the family carrying the VHL-R200W+R161Q mutations present normal hematological values. Table S4: Intra-domain hydrogen bonds are severely destabilized by the mutations. Table S5: The double mutant reduced the inter-domain mobility compared to the single one. Table S6: The pVHL/HIF-2α direct target genes are deregulated with a significantly ascending gradient by the pVHL mutants of increased severity. Table S7: The target genes of the pVHL/HIF-2α axis that are deregulated in renal cell carcinoma play a role in oncogenic pathways. Figure S1: Germline mutations in the VHL gene are associated with distinct phenotypes. Figure S2: (A) The crystallographic structure of pVHL contains a seven-stranded β-sandwich connected to four α-helices by a flexible linker. (B) The R200W mutation dramatically weakens hydrogen bonds established in the wild-type form between Arg200 and Glu134, and between Arg197 and Arg120. (C) The R161Q mutation indirectly influences crucial stabilizing interactions involving primarily Arg 167. Figure S3: VHL mRNA expression is equivalent in 786.O cells transduced by the different VHL inducible lentiviral constructs.
Supplementary Figures 1-4 from Natural Killer Cells Are Essential for the Ability of BRAF Inhibitors to Control BRAFV600E-Mutant Metastatic Melanoma
Authors: Ferrari de Andrade Lucas , Ngiow Shin F. , Stannard Kimberley , Rusakiewicz Sylvie , Kalimutho Murugan , Khanna Kum Kum , Tey Siok-Keen , Takeda Kazuyoshi , Zitvogel Laurence , Martinet Ludovic , Smyth Mark J.
Published: April 2023

Supplementary Figures 1-4. Supplementary Figure 1. LWT1 melanoma is sensitive to PLX4720 inhibition. Supplementary Figure 2. Anti-metastatic effects of PLX4720 requires NK cells. Supplementary Figure 3. PLX4720 does not increases IFN-γ production by NK cells. Supplementary Figure 4. PLX4720 does not increase NK cell-mediated cytotoxicity.
Supplementary Table 4 from O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells
Authors: Itkonen Harri M. , Minner Sarah , Guldvik Ingrid J. , Sandmann Mareike Julia , Tsourlakis Maria Christina , Berge Viktor , Svindland Aud , Schlomm Thorsten , Mills Ian G.
Published: April 2023

XLSX - 10K, Primer sequences and Taqman probes used in this study.
Supplementary Table 3 from O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells
Authors: Itkonen Harri M. , Minner Sarah , Guldvik Ingrid J. , Sandmann Mareike Julia , Tsourlakis Maria Christina , Berge Viktor , Svindland Aud , Schlomm Thorsten , Mills Ian G.
Published: April 2023

XLSX - 9K, Clinical parameters for prostate cancer samples used for transcript profiling.
Data Supplement from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets
Authors: Taguchi Ayumu , Taylor Allen D. , Rodriguez Jaime , Çeliktaş Müge , Liu Hui , Ma Xiaotu , Zhang Qing , Wong Chee-Hong , Chin Alice , Girard Luc , Behrens Carmen , Lam Wan L. , Lam Stephen , Minna John D. , Wistuba Ignacio I. , Gazdar Adi F. , Hanash Samir M.
Published: April 2023

Supplementary Table S3. Proteomic analysis of CT antigens in 38 NSCLC cell lines.
Supplementary Table 1 from O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells
Authors: Itkonen Harri M. , Minner Sarah , Guldvik Ingrid J. , Sandmann Mareike Julia , Tsourlakis Maria Christina , Berge Viktor , Svindland Aud , Schlomm Thorsten , Mills Ian G.
Published: April 2023

XLSX- 16K, Transcripts up-regulated during transition from normal prostate tissue to localized prostate cancer.
Data Supplement from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets
Authors: Taguchi Ayumu , Taylor Allen D. , Rodriguez Jaime , Çeliktaş Müge , Liu Hui , Ma Xiaotu , Zhang Qing , Wong Chee-Hong , Chin Alice , Girard Luc , Behrens Carmen , Lam Wan L. , Lam Stephen , Minna John D. , Wistuba Ignacio I. , Gazdar Adi F. , Hanash Samir M.
Published: April 2023

Supplementary Table S5. Prediction of binding affinity to HLA molecules in BIMAS and SYFPEITHI.
Data Supplement from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets
Authors: Taguchi Ayumu , Taylor Allen D. , Rodriguez Jaime , Çeliktaş Müge , Liu Hui , Ma Xiaotu , Zhang Qing , Wong Chee-Hong , Chin Alice , Girard Luc , Behrens Carmen , Lam Wan L. , Lam Stephen , Minna John D. , Wistuba Ignacio I. , Gazdar Adi F. , Hanash Samir M.
Published: April 2023

Supplementary Table S6. Allele frequency of HLA class I molecules associated with CT antigen panel in two populations from the United States.
Supplementary Figure 1 from O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells
Authors: Itkonen Harri M. , Minner Sarah , Guldvik Ingrid J. , Sandmann Mareike Julia , Tsourlakis Maria Christina , Berge Viktor , Svindland Aud , Schlomm Thorsten , Mills Ian G.
Published: April 2023

PDF - 277K, A) Inhibition of OGT expression with siRNA reduces the growth rate of LNCaP cells. B) Knockdown of OGT induces a compensating downregulation of MGEA5.
Data Supplement from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets
Authors: Taguchi Ayumu , Taylor Allen D. , Rodriguez Jaime , Çeliktaş Müge , Liu Hui , Ma Xiaotu , Zhang Qing , Wong Chee-Hong , Chin Alice , Girard Luc , Behrens Carmen , Lam Wan L. , Lam Stephen , Minna John D. , Wistuba Ignacio I. , Gazdar Adi F. , Hanash Samir M.
Published: April 2023

Supplementary Figure S1. Gene expression profiles of BEX, NXF, and TCEAL family genes in 207 lung cell lines.
Data Supplement from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets
Authors: Taguchi Ayumu , Taylor Allen D. , Rodriguez Jaime , Çeliktaş Müge , Liu Hui , Ma Xiaotu , Zhang Qing , Wong Chee-Hong , Chin Alice , Girard Luc , Behrens Carmen , Lam Wan L. , Lam Stephen , Minna John D. , Wistuba Ignacio I. , Gazdar Adi F. , Hanash Samir M.
Published: April 2023

Supplementary Figure S2. Methylation levels of CpG sites for VCX/Y genes.
Data Supplement from A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets
Authors: Taguchi Ayumu , Taylor Allen D. , Rodriguez Jaime , Çeliktaş Müge , Liu Hui , Ma Xiaotu , Zhang Qing , Wong Chee-Hong , Chin Alice , Girard Luc , Behrens Carmen , Lam Wan L. , Lam Stephen , Minna John D. , Wistuba Ignacio I. , Gazdar Adi F. , Hanash Samir M.
Published: April 2023

Legend for Supplementary Figures S1-S2.
Supplementary Figure S9 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: April 2023

Supplementary Figure S9. CtBP2 regulates androgen receptor co-repressors.
Data Supplement from Runx2 Is a Novel Regulator of Mammary Epithelial Cell Fate in Development and Breast Cancer
Authors: Owens Thomas W. , Rogers Renee L. , Best Sarah A. , Ledger Anita , Mooney Anne-Marie , Ferguson Alison , Shore Paul , Swarbrick Alexander , Ormandy Christopher J. , Simpson Peter T. , Carroll Jason S. , Visvader Jane E. , Naylor Matthew J.
Published: April 2023

Supplementary Data File containing: Supplementary Figure 1 - Failed lobuloalveolar development in Runx2 knockout transplanted mammary glands is retained at the first day postpartum. Supplementary Figure 2 - Generation and validation of Runx2 floxed;MMTV-cre mice. Supplementary Figure 3 - Runx2 floxed;MMTV-cre mice exhibit slightly delayed ductal elongation during puberty. Supplementary Figure 4 - Runx2 regulates luminal progenitor populations in Runx2 knockout transplanted mammary glands. Supplementary Figure 5 - Forced Runx2 expression does not perturb prolactin induced Stat5 activation in HC11 cells.
Supplementary Figure S8 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: April 2023

Supplementary Figure S8. Analysis of CtBP2 bindings in AR co-repressors by ChIP-seq.
Supplementary Figure S5 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: April 2023

Supplementary Figure S5. Validation of CtBP2 ChIP-seq study by conventional ChIP assay.
Data Supplement from Analysis of Chemotherapeutic Response in Ovarian Cancers Using Publicly Available High-Throughput Data
Authors: Bosquet Jesus Gonzalez , Marchion Douglas C. , Chon HyeSook , Lancaster Johnathan M. , Chanock Stephen
Published: April 2023

Legend for Supplementary Tables S1-S9 and Supplementary Figures S1-S7.
Supplementary Figure S4 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: April 2023

Supplementary Figure S4. ChIP-seq views of representative AR binding genes.
Supplementary Figure S3 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: April 2023

Supplementary Figure S3. CtBP2 promotes androgen-dependent prostate cancer cell proliferation.
Supplementary Figure S2 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: April 2023

Supplementary Figure S2. Effect of CTBP2 konckdown on androgen-mediated gene induction at early time point.
Supplemental Methods from Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers
Authors: Gan Gregory N. , Eagles Justin , Keysar Stephen B. , Wang Guoliang , Glogowska Magdalena J. , Altunbas Cem , Anderson Ryan T. , Le Phuong N. , Morton J. Jason , Frederick Barbara , Raben David , Wang Xiao-Jing , Jimeno Antonio
Published: April 2023

Supplemental Methods. Description of additional methods and procedures used in the study.
Supplemental Table and Figure Legends from Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
Authors: Tran Hung D. , Luitel Krishna , Kim Michael , Zhang Kun , Longmore Gregory D. , Tran David D.
Published: April 2023

Supplemental Table and Figure Legends. Legends to the supplemental table and figures
Supplementary Figure 6 from Molecular Modulation of Estrogen-Induced Apoptosis by Synthetic Progestins in Hormone Replacement Therapy: An Insight into the Women's Health Initiative Study
Authors: Sweeney Elizabeth E. , Fan Ping , Jordan V. Craig
Published: April 2023

Supplementary Figure 6. A. MCF-7:WS8 cells were transfected with an ERE-luciferase reporter construct for 24 hours, then treated with vehicle, 1µM ICI, 1µM R5020, 1µM RU486, 1nM E2, 1µM MPA, 1µM NETA, or combinations for 24 hours. ERE activity was measured by luciferase assay and normalized to vehicle control. Means represent samples in triplicate. B. MCF-7:WS8 cells were transfected with an ERE-luciferase reporter construct for 24 hours, then treated with vehicle, 1µM 4-OHT, 1µM R5020, 1µM RU486, 1nM E2, 1µM MPA, 1µM NETA, or combinations for 24 hours. ERE activity was measured by luciferase assay and normalized to vehicle control. Means represent samples in triplicate. Error bars too small to visualize.
Supplementary Figure 5 from Molecular Modulation of Estrogen-Induced Apoptosis by Synthetic Progestins in Hormone Replacement Therapy: An Insight into the Women's Health Initiative Study
Authors: Sweeney Elizabeth E. , Fan Ping , Jordan V. Craig
Published: April 2023

Supplementary Figure 5. MCF-7:5C cells were transfected with an ERE-luciferase reporter construct for 24 hours, then treated with vehicle, 1µM 4-OHT, 1nM E2, 1µM MPA, 1µM NETA, or combinations for 24 hours. ERE activity was measured by luciferase assay and normalized to vehicle control. Means represent samples in triplicate. Error bars too small to visualize.