bluuebunny/crossref_metadata_2025 huggingface dataset:
A STUDY ON TRENDS AND GROWTH OF PUBLIC AND PRIVATE SCHOOL EDUCATION IN KARNATAKA
Authors: Umesha K  , Dr. Mahesha M
Published: March 2024

This paper attempts to analyse the trends and growth of Public and Private School Education in Karnataka. For this purpose the study taken the time period between 2012-13 to 2021-22 from UDISE+ reports. The study found that the numbers of government primary schools are decreased from 22,897 to 20,903 in 2012-13 to 2021-22. For private aided primary schools the same trend is also observed they decreased from 245 to 195 in study period. The private unaided schools are also decreased from 3769 to 3226 during the study period. But the numbers of government primary schools are decreased higher compare to private aided and unaided schools and also found that the numbers of government upper primary schools are decreased in study period. In private aided Upper primary schools are decreased from 70 to 46, in study period. The private unaided schools are also decreased from 286 to 123 from 2012-13 to 2021-22. But the number of government Upper primary schools are decreased higher when compare to private aided and unaided schools.
KEY NOTES: Schools, Enrolments
Marx on the Periphery
Authors: Bianchi Bernardo
Published: March 2024

With reference to the Marx Seminars at the University of São Paulo, this chapter discusses the creation of a specific tradition in the social sciences that marks a crucial moment in the history of postcolonial and decolonial studies. By means of the concept of periphery, I reconstruct how this tradition refuted temporal and stadial dualisms. Moreover, I argue that the development of this new perspective in the social sciences must be understood in terms of its efforts to rethink Marx but also, and more importantly, by the need to rethink Brazil’s place in the world. Following this thread, I analyse Roberto Schwarz’s work as paradigmatic for a proper understanding of the centrality of the concept of periphery in these discussions.
The contribution of The Mindfulness and its relationship to risk-taking behavior in predicting sports injury among junior footballers in the Kingdom of Saudi Arabia
Authors: Al-Ghamdi Turki , Haggag Mohammed
Published: March 2024

The study aimed to identify the level of mental alertness and risk-taking behavior among soccer players, and to identify the relationship between mental alertness and risk-taking behavior, and to identify the differences in mental alertness and risk-taking behavior in the light of the following demographic variables (training age, degree of injury severity, number of injury times, centers  playing), and knowing the extent of the contribution of mental alertness and its relationship to risky behavior to predict sports injury in football youths, and the study used the descriptive approach, and the study population consisted of junior high-class clubs, and the sample included (300) youths, who were chosen in a simple random way, and the study was used in  The tools are a measure of mental alertness (Johnson, et al, 2016), a measure of risk-taking behavior (Abdel-Fattah, Mahmoud, 2019), and a form for the player's primary data.  There is an inverse (negative) statistically significant correlation between the total degree of mental alertness and risk-taking behavior and its dimensions.  Mental alertness and risk-taking behavior according to the following variables (training age - playing position), and there are statistically significant differences in mental alertness according to the number of sports injuries in the past and current season and the severity of the injury in favor of the players whose number of injuries is from (1-3), and whose severity  Their injury is light, and there are statistically significant differences in the risk-taking behavior according to the number of injury times for the two seasons and the severity of the injury in favor of the players whose number of times of injury is from (1-3) times and whose severity of injury is light, and since the higher the degrees of mental alertness among soccer players, this leads to  The decrease in risk-taking behavior among young people, which is reflected in the reduction of sports injuries, so mental alertness predicted the risk-taking behavior, which was reflected in the decrease in the rate of sports injuries.
The effect of neuromuscular training on improving some skill performances in basketball
Authors: Al Kitani Mahfoodha
Published: March 2024

The aim of the recent study was to examine the effect of neuromuscular training on performance layup and free throw shots performance among female basketball students. Study sample was female students of physical education and sport sciences department (Age 20.21±39.0) who volunteered to participate in this study. Thirty-seven female students participated in this study, where (21) female students were selected to be experimental group of neuromuscular exercises. A sample of (16) female students was used for the exploratory study from the original community. Results showed that neuromuscular exercises can improve the chosen basketball skills (free-throw and layup-shot shooting). The contribution of neuromuscular training in a positive way to the free-throw and layup-shooting skills.
Interaction between diet and genetics in patients with inflammatory bowel disease
Authors: Magro Daniéla Oliveira , Sassaki Ligia Yukie , Chebli Júlio Maria Fonseca
Published: March 2024

In this editorial, we comment on the article by Marangoni et al , published in the recent issue of the World Journal of Gastroenterology 2023; 29: 5618-5629, about “Diet as an epigenetic factor in inflammatory bowel disease”. The authors emphasized the role of diet, especially the interaction with genetics, in promoting the inflammatory process in inflammatory bowel disease (IBD) patients, focusing on DNA methylation, histone modifications, and the influence of microRNAs. In this editorial, we explore the interaction between genetics, gut microbiota, and diet, in an only way. Furthermore, we provided dietary recommendations for patients with IBD. The Western diet, characterized by a low fiber content and deficiency the micronutrients, impacts short-chain fatty acids production and may be related to the pathogenesis of IBD. On the other hand, the consumption of the Mediterranean diet and dietary fibers are associated with reduced risk of IBD flares, particularly in Crohn’s disease (CD) patients. According to the dietary guidance from the International Organization for the Study of Inflammatory Bowel Diseases (IOIBD), the regular consumption of fruits and vegetables while reducing the consumption of saturated, trans, dairy fat, additives, processed foods rich in maltodextrins, and artificial sweeteners containing sucralose or saccharine is recommended to CD patients. For patients with ulcerative colitis, the IOIBD recommends the increased intake of natural sources of omega-3 fatty acids and follows the same restrictive recommendations aimed at CD patients, with the possible inclusion of red meats. In conclusion, IBD is a complex and heterogeneous disease, and future studies are needed to elucidate the influence of epigenetics on diet and microbiota in IBD patients.
ALKBH5 suppresses autophagic flux via N6-methyladenosine demethylation of ZKSCAN3 mRNA in acute pancreatitis
Authors: Zhang Tao , Zhu Shuai , Huang Geng-Wen
Published: March 2024

BACKGROUND

Increasing evidence has demonstrated that N6-methyladenosine (m6A) RNA modification plays an essential role in a wide range of pathological conditions. Impaired autophagy is a critical hallmark of acute pancreatitis (AP).

AIM

To explore the role of the m6A modification of ZKSCAN3 in the regulation of autophagy in AP.

METHODS

The AP mouse cell model was established by cerulein-treated mouse pancreatic acinar cells (MPC-83), and the results were confirmed by the levels of amylase and inflammatory factors. Autophagy activity was evaluated by specific identification of the autophagy-related microstructure and the expression of autophagy-related genes. ZKSCAN3 and ALKBH5 were knocked down to study the function in AP. A m6A RNA binding protein immunoprecipitation assay was used to study how the m6A modification of ZKSCAN3 mRNA is regulated by ALKBH .

RESULTS

The increased expression of amylase and inflammatory factors in the supernatant and the accumulation of autophagic vacuoles verified that the AP mouse cell model was established. The downregulation of LAMP2 and upregulation of LC3-II/I and SQSTM1 demonstrated that autophagy was impaired in AP. The expression of ZKSCAN3 was upregulated in AP. Inhibition of ZKSCAN3 increased the expression of LAMP2 and decreased the expression of the inflammatory factors, LC3-II/I and SQSTM1 . Furthermore, ALKBH5 was upregulated in AP. Knockdown of ALKBH5 downregulated ZKSCAN3 expression and restored decreased autophagic flux in AP. Notably, the bioinformatic analysis revealed 23 potential m6A modification sites on ZKSCAN3 mRNA. The m6A modification of ZKSCAN3 mRNA was significantly decreased in AP. Knockdown of ALKBH5 increased the modification of ZKSCAN3 mRNA, which confirmed that ALKBH5 upregulated ZKSCAN3 expression in a m6A-dependent manner.

CONCLUSION

ALKBH5 inhibits autophagic flux through m6A demethylation of ZKSCAN3 mRNA in AP, thereby aggravating the severity of the disease.
Regional aspects of the restructuring of tourist flows in Europe in the 21st century
Authors: Ivanov Ivan
Published: March 2024

The impact of the COVID-19 pandemic on global tourism is not limited to the crisis in the tourism industry. The pandemic was accompanied by a spatial restructuring of tourist flows. The purpose of the study is to identify the features of this restructuring at the regional level of European countries under the influence of the pandemic and geopolitical factors. The information base for the study is statistics of tourist arrivals for 427 regions of European countries in the period from 2003 to 2022. The entire time interval of the study, in accordance with the peculiarities of the spatial restructuring of tourist flows, is divided into three periods (pre-pandemic, pandemic and the beginning of recovery from the pandemic). The analysis was carried out using a cartographic research method. The main trend of spatial restructuring of tourist flows from 2003 to 2019. was their partial redistribution in favor of the regions of the countries of the eastern part of Europe (post-socialist countries) and Turkey. During the pandemic (2020–2021), the greatest reduction in tourist flow characterized countries specializing in inbound tourism. Countries that managed to move towards increasing domestic tourist flows (including Russia) found themselves in a more advantageous position. In 2022, within foreign Europe, due to the persistence of sanitary restrictions in a number of countries at the beginning of the year, it was possible to observe a temporary redistribution of tourist flows from the central part of Europe to its periphery.
A Study of Electrolyte Imbalance in Diabetic Patients at a Teritary Care Hospital in Kerala
Authors: Sunil Antony
Published: March 2024

Introduction:   most of the diabetic patients will be having many complications and other co-morbidities. They often require multiple drugs for treatment. Diabetes mellitus itself, its complications and various medications all are related to development of electrolyte imbalance, which are often under-estimated or remain un-diagnosed.Objectives:   to assess the pattern of electrolyte imbalance in diabetic patientsMethod: This clinical study was done in the Department of general Medicine, Believers Church Medical College Hospital, Thiruvalla during 2016-17. Data were collected by random sampling from the first 100 adult diabetic patients with electrolyte imbalance, irrespective of their cause of admission.Results: Total number of patients were 125, male were 89 and female were 36. Mean age was 61.18 years with standard deviation of ± 13.15 years (Range 38- 80 years). Among the patients, the mean duration of the diabetes mellitus was 10.06 years with standard deviation ± 7.05 years. Over all 73% of patients had some sort of electrolyte imbalance, irrespective of cause of admission. Hyponatraemia was the most common electrolyte imbalance in this study (75%), followed by hypomagnaesemia (35%), hypokalaemia (32%) and hyperkalaemia (13%). In 10% cases there were hyponatraemia, hypokalaemia and hypomagnaesemia.Conclusion: it can be concluded that, electrolyte imbalance is common in diabetic patients. Serum electrolytes should be checked regularly in diabetic patients irrespective of their purpose of admission.
Comparison of Tuberculin Skin Test Versus Newer Quantiferon TB Gold Assay Method in Screening for Latent Tuberculosis Infection in Various High Risk Groups
Authors: Gordhanbhai L Gondalia
Published: March 2024

Aim: The aim of present study to evaluate the QuantiFERON-TB gold assay and tuberculin skin test to recognize tuberculosis infection amongst tuberculosis patient contact.Methodology: A total of 55 tuberculosis patients contacts were utilized for research, blood were pinched and practices by utilizing the QuantiFERON-TB gold assay pursue by insistent management of tuberculin skin test solution in subjects forearm.All accessible associates were asked to giveblood samples for Latent tuberculosis infection intest.Results: QuantiFERON-TB gold assay distinguishLatent tuberculosis infection with sensitivity of 88.81% and specificity of 89.9%. Tuberculin skin test: Sensitivity 67.9%, Specificity 15.9%.Conclusion: Equallytuberculin skin test and QuantiFERON-TB gold assay can be utilized to recognize TBdisease or Latent tuberculosis infection. The present assessment of tuberculin skin test&QuantiFERON-TB gold assay consequence bears thatQFT-G assay supply additional accurate results than tuberculin skin test in revealing of Latent tuberculosis infection.
Case Report - Anesthetic Challenges of Congenital Diaphragmatic Hernia Repair in an Adult
Authors: Smriti Sinha, Varghese Zachariah K
Published: March 2024

Congenital diaphragmatic hernia (CDH) usually presents in the neonatal period with respiratory distress. The presentation in adults varies from asymptomatic to unexplained symptoms, which makes CDH difficult to diagnose. We report an anaesthetic management of CDH repair in an adult patient, who presented with abdominal pain. CDH was an incidental finding. The patient was planned for laproscopic CDH repair, keeping thoracotomy as alternative. Anaesthetic management was complicated by pulmonary hypoplasia on affected side, pulmonary hypertension and need of one lung ventilation. Postoperatively analgesia was also a challenge to prevent atelectasis.
ОСОБЕННОСТИ СИНДРОМА ВОССТАНОВЛЕНИЯ ИММУНИТЕТА ЦЕНТРАЛЬНОЙ НЕРВНОЙ СИСТЕМЫ В ПРОЦЕССЕ ЛЕЧЕНИЯ ИНФЕКЦИИ, ВЫЗВАННОЙ ВИРУСОМ ИММУНОДЕФИЦИТА ЧЕЛОВЕКА
Authors: Улюкин И.М. , Орлова Е.С. , Сечин А.А.
Published: March 2024

В статье рассмотрены особенности синдрома восстановления иммунитета центральной нервной системы в процессе лечения инфекции, вызванной вирусом иммунодефицита человека в настоящее время, обсуждены некоторые перспективы лечения и медико-психологического сопровождения.
Решение задач с прикладным содержанием в профильном ЕГЭ по математике
Authors: Баадыр Д.П.
Published: March 2024

Задачи с прикладным содержанием, включенные в 2020 году в экзаменационные работы ЕГЭ по математике под номером 9, представляют собой задачи на анализ явления, описываемого формулой функциональной зависимости. При подготовке к ЕГЭ многие старшеклассники считают, что задание 9 является заданием из физики. Ведь с физикой дружат не все, и поэтому считают, что задание является трудной. Чтобы решить задачи с прикладным содержанием можно разделить на несколько шагов: 1. анализ условия и вычленение формулы, описывающей заданную ситуацию, а также значений параметров, констант или начальных условий, которые необходимо подставить в эту формулу; 2. математическая интерпретация задачи; 3. анализ полученного решения. Обратимся к примерам.
ЦИТРАТ КОФЕИНА. ПОЧЕМУ ОДИН ИЗ САМЫЙ ВОСТРЕБОВАННЫХ И ЭФФЕКТИВНЫХ ПРЕПАРАТОВ ОСТАЕТСЯ ПРЕДМЕТОМ СПОРОВ?
Authors: Коробейников Н.А. , Коротаева Н.В.
Published: March 2024

Сегодня кофеин цитрат используется во всех отделениях патологии новорожденных, а также в отделениях реанимации и интенсивной терапии по всему миру. Множество статей и научных работ доказали его эффективность и незаменимость в практике врача-неонатолога, но как и любой препарат, кофеин цитрат имеет особенности в дозировке и специфические побочные эффекты на организм новорожденного. Фармакология кофеина известна и не является тайной, но использование кофеина в “исключительных” клинических случаях до сих пор вызывает противоречия и споры. В данной обзорной статье будут рассмотрены современные клинические испытания кофеина цитрата в клинических ситуациях, сравнение действия цитрата кофеина с теофиллином, обзор литературы, описание современной фармакологии и обзор недавних научных статей.
БАЯННО-АККОРДЕОННОЕ ИСКУССТВО, КАК ИНСТРУМЕНТ УСИЛЕНИЯ МЕЖКУЛЬТУРНОГО ВЗАИМОДЕЙСТВИЯ МЕЖДУ РОССИЕЙ И КИТАЕМ
Authors: Ван Ц.
Published: March 2024

В статье рассматривается генезис развития межкультурного взаимодействия между Россией и Китаем. Отмечено, что музыкальное искусство в данном направлении прошло, как спады, так и подъемы и в целом данный процесс сопоставим в обеих странах. Так, на сегодняшний день прослеживается интеграция культур, обусловленная внешней и внутренней политикой России и Китая. Несмотря на сравнительно общий вектор развития, взаимообмен идеями и опытом в педагогической среде, растущим взаимным потоком студентов, а также наличием в России уникальной системы обучения педагогическому мастерству, нацеленному на китайскую аудиторию, в будущем данный процесс замедлится, что обусловлено желанием Китая адаптировать инструменты баянно-аккордеонной группы под особенности культурной среды: в будущем звучание китайского аккордеона и баяна станет более уникальным и узнаваемым. Именно принятие данной тенденции Россией положит начало новому этапу взаиморазвития культур.
Педагогическая профилактика агрессивного поведения младших школьников
Authors: Игнатова Ю.Е.
Published: March 2024

в статье рассматривается проблема агрессии младших школьников; что влияет на детей, какие проблемы возникают, какие методики применить для решения данной проблемы
ВНЕУРОЧНАЯ ЗАНЯТОСТЬ МЛАДШИХ ШКОЛЬНИКОВ КАК РЕШЕНИЕ ПРОБЛЕМЫ АДАПТАЦИИ К ШКОЛЕ
Authors: Клейменова А.К.
Published: March 2024

Статья рассматривает проблемы, связанные с психологическим и физическим развитием первоклассников, и предлагает пути их решения через организацию внеурочной деятельности. Также обсуждаются возможные негативные аспекты внеурочной деятельности в школе и дополнительных образовательных учреждениях. Авторы обращают особое внимание на учебную нагрузку и предлагают рассмотреть способы преодоления трудностей вне школы в целях лучшего физического и психического развития детей. При этом особое внимание уделяется созданию оптимальных условий для организации внеурочной деятельности и развитию детей.
Исследование распространенности мигрени среди других видов головной боли у студентов медицинского вуза
Authors: Орлина М.А. , Марковская Д.В. , Рудакова А.Ю. , Назимко О.С.
Published: March 2024

В настоящее время головными болями страдает около 50% населения всего земного шара, однако все головные боли можно классифицировать на разные виды. Данное исследование направлено на изучение распространенности мигреней среди учащихся медицинского ВУЗа и именно среди тех учащихся, которые страдают головными болями различного характера.
SOCIAL HEALTH INSURANCE ADMINISTRATION BODY PARTICIPANTS’ SATISFACTION ON DECISION TO USE MOBILE APPLICATION
Authors: Ridiarsih Ridiarsih , Nugroho Trisno Arifin , Ahsani Muhammad Nabhan , Pasaribu Popy Novita
Published: March 2024

Mobile JKN is an application developed by Social Health Insurance Administration Body  to provide easy access to information about the National Healthcare Insurance Program (JKN Program). The number of participants in the Social Security Agency on Health (BPJS Health) has almost reached 250 million people. The government must manage public services so Social Security Agency on Health participants can access health facilities conveniently. The study aims to analyze the Social Security Agency on Health participants’ satisfaction with the decision to use the Mobile JKN application using the Expectancy Disconfirmation Model (EDM). EDM described how perceived expectations and performance influence public satisfaction. The study method is quantitative, with the study unit being Social Security Agency on Health participants and locus in Bogor. Structural Equation Modeling (SEM), a multivariate data analysis technique, was used in this study to examine the data and assess the intricate relationships between the constructs and indicators. The data processing technique uses SmartPLS. The finding shows that using the mobile JKN application has positively impacted user satisfaction. The Social Security Agency on Health participants were satisfied after utilizing the Mobile JKN application to access healthcare services.
DESEMPENHO FISIOLÓGICO DE SEMENTES DE CULTIVARES SOJA CONVENCIONAL EM FUNÇÃO DO TAMANHO E TEOR DE UMIDADE NA GERMINAÇÃO
Authors: Sartori Dameto Larissa , Krzyzanowski Francisco Carlos , Eustáquio de Sá Marco , Moreira Adonis , Alexandra Cardoso Moraes Larissa
Published: March 2024

Quality test protocols for soybean seeds recommend a period of soaking and preconditioning without detailing the size of the seeds to be evaluated, as seeds of different sizes reach different degrees of humidity in each period owing to differences in their initial moisture level and size. Determining the degree of seed moisture during the preconditioning period is important when conducting accelerated aging, tetrazolium, and primary root protrusion tests. The objective of this study was to evaluate the physiological performance of two conventional soybean cultivars (BRS 284 and BRS 511) with three seed sizes (6.0, 6.5, and 7.0 mm) and three moisture levels, adjusted to 10%, 12%, and 14% and a control condition with 8.8% moisture. The experimental design was a randomized block scheme in a factorial arrangement of (3×3)+1 involving seed size and moisture. Regardless of the cultivar and moisture content, seeds with large diameters were more resistant to changes, such as accelerated aging, and resulted in larger seeds and higher numbers of developed seedlings than seeds with small diameters.
BIOSSEGURANÇA NO DESENVOLVIMENTO DE VACINAS BIOFÁRMACOS E KITS DE DIAGNÓSTICO: BIOSAFETY IN THE DEVELOPMENT OF VACCINES, BIOPHARMACEUTICALS AND DIAGNOSTIC KITS
Authors: Senna JPM , Muller Rodrigo
Published: March 2024

O desenvolvimento e produção de imunobiológicos (vacinas, biofármacos e imunodiagnóstico), requer uma ampla gama de medidas de biossegurança para garantir a segurança de seus funcionários, do produto final e dos consumidores destes produtos. Neste trabalho, procuramos abordar os aspectos da biossegurança nas etapas envolvidas neste processo, segundo nossa experiência trabalhando no Instituto de Tecnologia em Imunobiológicos –Bio-Manguinhos –FIOCRUZ.
COMPORTAMENTO SOCIAL ALTERADO EM RATOS RECUPERADOS DE DESNUTRIÇÃO PROTEICA
Authors: Minazaki CK , Noronha PB , Orsi RB , Menão MC , Felippe PAN , Leanza EC , Silva CA
Published: March 2024

Objetivo: Foi analisado o comportamento social de ratos alimentados com dieta normoproteica e recuperados (as) após desnutrição induzida pelo consumo de dieta hipoproteica. Método: Foram avaliados parâmetros sensoriais utilizados pelos ratos no reconhecimento de seus pares no lócus de convívio sendo analisados o paradigma intruso-residente e o labirinto em cruz elevada. Resultado: Foi observado que somente no grupo recuperado de desnutrição houve redução na capacidade de reconhecer seus pares, após exposição consecutiva de curta duração, intensa manifestação de agressividade e incapacidade de julgar o perigo no labirinto em cruz elevada. Conclusão: Possivelmente o comportamento encontrado possa refletir no comprometimento na maturação do sistema nervoso central, devido à falta de aminoácidos em uma fase importante do desenvolvimento das diferentes áreas do encéfalo.
DIAGNÓSTICOS E INTERVENÇÕES DE ENFERMAGEM PARA PACIENTES VÍTIMAS DE ACIDENTE VASCULAR ENCEFÁLICO
Authors: Masulo de Lima Wagner , de Oliveira Machado Elisiane , da Costa Michielin Fabiano , Santos Suimara , Daniel Chassot Maicon , Letícia de Negreiros Kerschner Cíntia , Silva da Rosa Fabio , Aparecida Furlan Inchauspe Juciane , Dornelles Santarem Michelle , Andriele Wachter Djulia
Published: March 2024

Introdução: O Acidente Vascular Encefálico (AVE) é a 2ª causa de morte no mundo, sendo assim, é uma questão de saúde pública que causa restrições físicas e psicológicas ao paciente e também prejuízo aos familiares. Para tanto, é necessário que o enfermeiro implemente os Diagnósticos de Enfermagem (DE) para cada paciente. Objetivo: Analisar os registros de enfermagem em prontuários de pacientes com AVE, hospitalizados em unidade de internação vascular. Método: Trata-se de uma pesquisa de caráter quantitativo, transversal e retrospectivo, onde foram coletados dados em prontuários, referentes ao Processo de Enfermagem (PE), diagnósticos e intervenções de enfermagem dos pacientes hospitalizados na unidade de internação vascular. Foram analisados prontuários de janeiro de 2016 a dezembro de 2017. Para a coleta de dados foi utilizado um instrumento contendo variáveis que caracterizam o perfil clínico e social destes pacientes e os diagnósticos e intervenções de enfermagem. O projeto foi aprovado pelo Comitê de Ética em Pesquisa da Santa Casa de Misericórdia de Porto Alegre e do Centro Universitário Metodista IPA. Resultados: A amostra constou de 104 pacientes com média de idade de 68 anos, com taxas do sexo masculino de 53% (n=55), e o feminino de 47% (n=50). O tipo de AVE mais frequente foi o AVE Isquêmico com taxa de 81%, e 83% deles não receberam trombolíticos. O tempo de chegada até a unidade de internação foi em média de 16 horas e 51 minutos e o tempo médio de internação foi de 5,7 dias nesta unidade, sendo a maioria proveniente de Porto Alegre (91%). O destino destes pacientes foi de 91% para domicilio, 6% foram a óbito e os outros 3% para outros destinos. Os principais DE estabelecidos: Risco de trauma vascular (50,9%), Perfusão tissular periférica ineficaz (41,3%) e Mobilidade física prejudicada (27,8%). E as principais intervenções foram: manter cuidados de enfermagem (89,4%), observar, registrar e comunicar alterações (67,3%) e manter grades elevadas (20,1%). Conclusão: o estudo contribuiu para se conhecer a realidade dos registros em uma unidade de internação para pacientes vítimas de AVE e promover discussão e qualificação do PE com ênfase nas etapas do DE e elaboração e implementação dos cuidados de enfermagem.
DISFUNÇÃO METABÓLICA ASSOCIADA À DOENÇA HEPÁTICA ESTEATÓTICA: CONSUMO DE BEBIDAS RICAS EM FRUTOSE, NEOLIPOGÊNESE E INFLAMAÇÃO
Authors: Costa Danilo Duarte , Ferreira A. L. B. R , Morais E. L. A. , Gomes Gabriela Sanglard Mafra , Mota Emanuelly Botelho Rocha
Published: March 2024

RESUMO Objetivo: avaliar a relação entre a disfunção metabólica, o consumo de frutose e a etiopatogênese da doença hepática gordurosa. Métodos: Trata-se de uma revisão integrativa da literatura, com consulta às bases de dados PUBMED, SciELO e Biblioteca Virtual em Saúde (BVS). Selecionou-se artigos publicados entre 2018 e 2023, de acordo com sua relevância para o objetivo do estudo e adequação com o tema, totalizando 12 artigos. Resultados: A Doença Hepática Esteatótica Associada à Disfunção Metabólica (MASLD) afeta pessoas de todas as idades, gêneros e etnias, apresentando forte relação com a síndrome metabólica. A resistência à insulina desempenha um papel fundamental no desenvolvimento da doença, levando ao acúmulo de lipídeos no fígado. O consumo excessivo de frutose, especialmente em bebidas açucaradas, está associado ao desenvolvimento da condição devido a sua influência na resistência à insulina, na neolipogênese e na inflamação hepáticas. A dieta e o estilo de vida desempenham um papel crucial na prevenção e no manejo da MASLD. Conclusão: A MASLD é uma condição multifatorial com uma forte ligação a fatores genéticos e ao estilo de vida, incluindo o consumo de frutose. Para sua prevenção e manejo, deve-se adotar um estilo de vida saudável, com controle de peso, prática regular de atividade física e modificação da dieta, destacando a importância de mitigar os fatores de risco metabólicos para melhorar a saúde hepática.
ALTERAÇÕES NO EQUILÍBRIO FUNCIONAL APÓS PROGRAMA DE JOGOS E EXERCÍCIOS COM NINTENDO WII EM PESSOAS COM PARALISIA CEREBRAL
Authors: Mendes Eugénia , Valfreixo Maria da Conceição Gomes dos Santos , Novo André , Espuela Fidel Lopez , Preto Leonel São Romão
Published: March 2024

Objetivo: Investigar as mudanças no equilíbrio funcional em pessoas com paralisia cerebral (PC) após a participação em um programa de jogos e exercícios utilizando a plataforma Nintendo Wii. Métodos: Foi conduzido um estudo quase-experimental em um centro de apoio para pessoas com deficiência no norte de Portugal, envolvendo 21 participantes com PC. Durante um período de 8 semanas, implementou-se um programa de exercícios e jogos interativos. Como instrumentos de avaliação do equilíbrio utilizámos a Berg Balance Scale (BBS) e o teste Timed Up and Go (TUG). Resultados: Os resultados da BBS foram no momento baseline de 47,8 (±5,6) pontos passando para 52,6 (±3,7) no final do programa de treino (p<0,05). Os tempos Up and Go melhoraram significativamente entre avaliações (p<0,05). Verificámos ainda uma melhoria da correção do centro de gravidade em 13 participantes. Conclusão: O uso de jogos e realidade virtual pode potencializar a adesão a programas de reabilitação em indivíduos com condições incapacitantes. Os resultados deste estudo indicam melhorias significativas na função de equilíbrio.
ANCHIETEA SALUTARIS COMO ALTERNATIVA NO TRATAMENTO DA PSORÍASE
Authors: Araújo Michael Daniel Pereira , Andrade De Ávila Rogerio
Published: March 2024

Este estudo visa explorar o potencial terapêutico da Anchietea salutaris no tratamento da psoríase, uma doença dermatológica crônica e complexa, que afeta significativamente a qualidade de vida dos pacientes. Foi realizado um levantamento bibliográfico sistemático nas bases de dados científicas, incluindo PubMed, Scopus, Web of Science, e Google Scholar, com o uso das palavras-chave “psoríase”, “tratamento”, “Anchietea salutaris”, e “uso medicinal de plantas”. Os estudos revisados destacam a psoríase como uma doença inflamatória crônica, com uma patogênese imunomediada e genética. A Anchietea salutaris, utilizada tradicionalmente no tratamento de diversas afecções, demonstrou possuir propriedades anti-inflamatórias e imunomoduladoras, sugerindo uma ação terapêutica potencial contra a psoríase. Os extratos da planta inibiram a liberação de histamina e apresentaram atividade antihistamínica, além de conter compostos como triterpenos pentacíclicos e fitol, que podem atuar na modulação da resposta imune e inflamatória na pele psoriática. A Anchietea salutaris emerge como uma alternativa promissora para o tratamento da psoríase, alinhada às necessidades de terapias mais naturais e com menores efeitos colaterais.
DISJUNÇÃO DO ANEL MITRAL E O RISCO DE MORTE SÚBITA CARDÍACA: UMA REVISÃO DA LITERATURA
Authors: Reis Rayanne Emily Silva , Carneiro Heloísa Andrade Luz , Ferreira Sthéfanny Alves , Lopes Jesana Costa , Nunes Genildo Ferreira
Published: March 2024

Introdução: A Disjunção do Anel Mitral, ocorre quando o local de inserção normal sofre uma deslocação na estrutura anular do miocárdio basal. Pacientes que apresentam esse processo, possuem uma maior chance de desenvolver arritmias ventriculares mais graves, aumentado consequentemente, o risco para a morte súbita cardíaca. Objetivo: Elencar, sintetizar e discutir a existência da relação da Disjunção do Anel Mitral com a morte cardíaca súbita. Métodos: Trata-se de uma revisão de literatura a partir de artigos, em inglês, português e espanhol, obtidos nos bancos de dados Lilacs, Pubmed e Scielo, publicados entre os anos de 2013 e 2023. Os descritores foram “mitral disjunction OR mitral valve prolapse” AND “sudden cardiac death”. Estes deveriam estar contidos no título, resumo ou palavra-chave. Resultados: Foram identificados 291 artigos, dos quais 07 preencheram os critérios de seleção. Os grupos amostrais dos estudos selecionados variaram entre 18 a 2.607 indivíduos. Os resultados se mostraram mais relevantes em relação a Disjunção do Anel Mitral e a morte cardíaca súbita, sendo que mais de 40% das amostras pesquisadas apresentaram arritmias como fator predisponente para a morte súbita cardíaca. Conclusão: Os estudos demonstraram que a morte cardíaca súbita está relacionada com eventos arritmogênicos graves na disjunção do anel mitral, além da forte associação com o Prolapso da Valva Mitral.
Privacy Protection Based on Federated Learning
Authors: Liu Bin , Eric B. Blancaflor  , Fang Tianke , Cao Limin
Published: March 2024

With the development of artificial intelligence technology, more and more fields will collect relevant user data, and provide users with a better experience through data analysis. But there are also risks involved in the process of data collection, namely how to protect personal privacy data. To address this issue, this study combined differential privacy, convolutional neural networks, and federated averaging algorithms to construct a privacy protection model. The study first utilized the federated average algorithm to handle data imbalance, ensuring that each analyzed data is in a balanced state. Then, based on of data balancing, a new algorithm model was constructed using differential privacy and convolutional neural networks. Finally, it utilized a number of public datasets to verify the role of the model in privacy protection. The results showed that the model can achieve recognition accuracy of 97.27% and 93.15%, respectively , for data under the influence of privacy budget and relaxation factor. Meanwhile, the classification accuracy of the model for data can reached 95.31%, with a regression error of 9.03%. When the local iteration number of the device was 30, the testing accuracy can reached 95.28%. This indicates that methods on the grounds of federated averaging algorithm and differential privacy can maintain the accuracy of the model while protecting user privacy. The application research of models has strong practical significance.
Transfer Function and Transient Response Analysis of Active Inrush Current Limiting Circuit on P-MOSFET with Equivalent RLC Series Circuit Load of Inverter
Authors: Haryanti Munnik , Nugroho Adi , Yulianti Bekti , Dewanto Yohannes
Published: March 2024

Inrush current is a transient current surge when a piece of electrical equipment is turned on. One of the solutions is a P-MOSFET-based active inrush current limiter, which will be analyzed with KiCad software to analyze the transient response graph and a Python program to analyze the transfer function graph. From the observation, the circuit could reduce the inrush current amount which was initially ranging from 12mA – 12A to below 500nA, with a very low amount of ripple (under 100nA peak-to-peak). The transfer function graph from the RLC load represents its transient response graph, and the transfer function graph of the inrush current limiter with load creates a logarithm function.

Keywords: inrush current, P-MOSFET, transient response, transfer function, ripple
Factors affecting need for hormone replacement after thyroid lobectomy
Authors: Şentürk Adem , Harmantepe Ahmet Tarık , Gönüllü Emre , Demir Hakan , Cantürk Alp Ömer , Cünük Emine Sena , Yavuz Akça Tuba
Published: March 2024

Aims: The aim of this study is to determine the incidence and risk factors of postoperative hormone replacement in patients who underwent thyroid lobectomy.

Methods: Patients who underwent thyroid lobectomy in our clinic between January 2015 and January 2021 were retrospectively scanned. Age, gender, preoperative hemogram and thyroid function tests (TFT) were screened. During postoperative follow-up, current TFT, height, weight, thyroid hormone replacement status and hypothyroidism symptoms were questioned. Pathology reports were examined.

Results: The pathology (patological examination results of specimen of the patients) were nodular hyperplasia in 81.1% (n=30) and Papillary thyroid carcinoma (PTC) in 18.9% (n=7). While the need for hormone replacement developed in 37.8% (n=14) of the patients in the postoperative follow-up, it did not develop in 62.2% (n=23). It was determined that high preoperative thyroid stimulating hormone (TSH) significantly increased the need for postoperative hormone replacement (p
Pioglitazone/Exenatide/SGLT-2 inhibitor combination therapy versus insulin therapy in patients with poorly controlled type 2 diabetes
Authors: Düğer Hakan , Ucan Bekir
Published: March 2024

Aims: We aimed to investigate the changes in glycemic status and beta cell function in type 2 diabetes mellitus (T2DM) patients with poor glycemic control despite receiving basal/bolus insulin therapy when switched from insulin therapy to combination therapy [exenatide/pioglitazone/sodium glucose cotransporter 2 inhibitor (SGLT-2i)].

Methods: A retrospective examination was made of the data of 64 patients, aged >18 years, diagnosed with T2DM, who were being followed up in the endocrinology outpatient clinic and were switched from basal/bolus insulin therapy to triple combination therapy. At the time of the patients changing to combination therapy, the glycosylated hemoglobin (HbA1c) value was ≥8.5% and fasting c peptide value was within the normal reference range. The anthropometric data of the patients, and glycemic and biochemistry values with modified homeostastis model assessment β (HOMA-β) levels were compared before the combination therapy and at 6 months after.

Results: Compared to the baseline values, a decrease was seen after 6 months in the values of body weight (89.6±5.8 vs. 83.8±3.6, p=0.015), body mass index (BMI) (38.3±2.7 vs. 33.5±1.9, p=0.011), and waist circumference (105.6±8.8 vs. 99.7±6, p=0.027). A decrease was determined in fasting blood glucose (FBG) (197±27.3 vs. 129±13.1, p
Analgesic effects of thoracic fascial plane blocks in postoperative pain management following cardiac surgery with sternotomy: a retrospective study
Authors: Zengin Emine Nilgün , Salman Nevriye
Published: March 2024

Aims: Acute poststernotomy pain is very severe and causes adverse hemodynamic disturbances. Various thoracic fascial plane blocks are used in the management of this pain. This study aimed to compare the analgesic effects of conventional analgesic methods and thoracic fascial plane blocks in the treatment of post-sternotomy pain.

Methods: Patients aged over than 18 years and with American Society of Anesthesiologists (ASA) physical status I-II-III who underwent elective cardiac surgery with sternotomy in 2022-2023 were included in this retrospective study. Patient records were categorized into groups based on the regional analgesia preferences applied. The groups are as follows: Group I: Patients without any blocks. Group II: Patients who received parasternal block (PSB). Group III: Patients who received serratus anterior plane block (SAPB). Group IV: Patients who received erector spinae plane block (ESPB). Then, the patients’ demographic data, laboratory data, Behavioral Pain Score (BPS) values, Visual Analog Scale (VAS) values, and additional analgesia needs were recorded and compared.

Results: The files of 128 patients were included in the study. The patients are statistically similar in terms of demographic data and surgical characteristics. Remifentanil consumption, BPS values, VAS values, and the need for additional analgesia were statistically lower in the groups in which thoracic fascial plane blocks were applied compared to the group in which conventional analgesia was applied.

Conclusion: As a result, thoracic fascial plane blocks, which have been used increasingly frequently in recent years, can provide more effective analgesia than conventional analgesia methods in cardiac surgery. Additionally, considering enhanced recovery after surgery protocols, these blocks may reduce undesirable side effects by limiting the need for opioids in the perioperative period. Since PSB and SAPB can be applied in the supine position, they may be more advantageous than ESPB in terms of ease of application.
Cooperating in asymmetric contexts: an interdisciplinary approach to ST&I negotiations involving developing countries
Authors: Leite Iara
Published: March 2024

What drives the implementation of international cooperation in science, technology and innovation (ST&I)? Why do negotiations in some areas evolve to concrete measures and others do not? What factors explain variations in implementation in initiatives with different countries? At which circumstances can implementation be effective from the point of view of developing countries? To answer those questions this paper proposes an interdisciplinary theoretical framework that draws on studies from international politics, political economy, foreign policy analysis, science and technology policy and history of science and technology. The paper departs from conceptual and theoretical elaborations on power and shows how they relate to ST&I and asymmetric negotiations involving developing countries and powerful counterparts. It concludes by an attempt to integrate key points raised by the revised literature, proposing four patterns on implementation and non-implementation and illustrating them with suggested cases for future research on Brazil-United States nuclear and aeronautic agreements and Brazil-China space and agriculture agreements.
Experiências recentes da União Europeia e dos Estados Unidos em bioeconomia e oportunidades para o Brasil
Authors: Bueno Adriana Mesquita Corrêa , Torres Danielle Alencar Parente
Published: March 2024

Este artigo apresenta os exemplos do desenvolvimento recente da bioeconomia na União Europeia (UE) e nos Estados Unidos com o intuito de identificar elementos importantes que possam contribuir para o desenvolvimento da bioeconomia no Brasil. O quadro analítico abrange quatro categorias de análise: antecedentes; governança, que busca examinar a estratégia nacional, as políticas e os atores domésticos da bioeconomia na UE e nos Estados Unidos; mensuração e monitoramento; e os principais setores e pesquisa, desenvolvimento e inovação (PD&I) da bioeconomia. Percebe-se que a coordenação entre os atores é fundamental para que haja união de esforços e avanços; também é importante definir se o núcleo da bioeconomia brasileira terá uma abordagem mais holística, como na UE, ou mais voltada para novas tecnologias, ferramentas e ciências, como nos Estados Unidos. Exemplos de parcerias público-privadas, como na UE, e programas de compras públicas, como nos Estados Unidos, são importantes mecanismos de incentivo para o desenvolvimento e o Brasil poderá aprender com essas experiências para construir seus próprios mecanismos.
A Interculturalidade como forma de integração da América Latina: um estudo dos programas Ibercultura Viva e Mestizo
Authors: Mendes Daniel
Published: March 2024

Este artigo analisa como a interculturalidade tem sido desenvolvida como forma de integração da América Latina. A partir da metodologia do estudo de casos, buscamos compreender a experiência recente de dois programas interculturais realizados nestes trópicos: o IberCultura Viva, desenvolvido pela Secretaria Geral Ibero-americana (Segib), e o Mestizo, desenvolvido pelo British Council. Para esta compreensão, adotamos como principal arcabouço teórico e fio condutor de discussão os estudos sobre hibridação realizados pelo antropólogo Canclini (2008). Entre os relevantes resultados obtidos, destacamos a percepção dos diversificados espaços comuns criados por ambas as iniciativas, que possibilitam muito mais que meras misturas culturais, isto é, estabelecem novos pertencimentos e contribuem para o desenvolvimento sociocultural e econômico das regiões e agentes envolvidos. Assim, são efetivadas duas formas de integração da América Latina: entre países da região e entre um país latino-americano e qualquer outro do mundo.
ntegração e desenvolvimento econômico da América Latina: uma interpretação das contribuições de Celso Furtado
Authors: Braga Márcio Bobik , Figueiredo Alexandre Ganan de Brites
Published: March 2024

Este artigo tem como objetivo analisar o papel da integração econômica regional para o desenvolvimento econômico da América Latina, tomando como referência as contribuições de Celso Furtado. A partir de elementos teóricos e empíricos (históricos), pretende-se demonstrar que os argumentos de Celso Furtado sobre a integração dos países latino-americanos envolvem uma complexa adequação dos projetos nacionais, econômicos e políticos em torno de um projeto regional.
La Brecha tecnológica regional y el caso de la producción de vacunas en Argentina y Brasil
Authors: Brenner Lautaro Zubeldia , Sly Maria José Haro
Published: March 2024

Este artigo se propõe a discutir o papel da ciência, da tecnologia e da inovação (CTI) na região fazendo um estudo de caso da produção de vacinas na Argentina e no Brasil tendo em conta o contexto da biotecnologia latino-americana. O artigo apresentará dados sobre a assimetria em CTI no Mercado Comum do Sul (Mercosul), comparando a região com as maiores potências tecnológicas contemporâneas dos Estados Unidos e China. Analisaremos a dependência tecnológica no marco da pandemia de covid-19 na região e desenvolveremos os casos da Argentina e do Brasil na produção de vacinas. Finalmente, propõe-se a necessidade de se avançar com a implementação de uma agência reguladora de medicamentos do Mercosul, buscando a soberania sanitária para facilitar a produção de medicamentos, insumos e vacinas na região.
THE IMPACT OF MECHANICAL VIBRATIONS ON HYDRAULIC VALVES AND THE POSSIBILITY OF REDUCING THE EFFECTS
Authors: Stosiak Michał , Skačkauskas Paulius , Deptuła Adam
Published: March 2024

The paper shows that mechanical vibrations occur in a wide frequency range in the hydraulic systems operating in the real world. Hydraulic valves are also exposed to these vibrations. The paper gives examples of vibration sources and suggests that the influence of vibrations on hydraulic valves could be reduced. Particular attention was paid to the vibrating proportional distributor. The amplitude-frequency spectrum of pressure pulsation in a hydraulic system with a vibrating proportional distributor was analysed. During the tests, the frequency of external mechanical vibrations acting on the proportional distributor and their direction was changed.
Monitoring growth and predicting crop yield through UAV-mounted spectral camera analysis of the interplay between soil compaction and vegetation index
Authors: Huu Bui Van , Hieu Ngo Quang , Hieu Luu Trong
Published: March 2024

This paper aims to introduce a prediction of crop yield based on relationship between soil compaction and vegetation index. The soil compaction increasingly with depth, which was calculated manuallyunevenly distributed in the field. The NDVI/NDRE was conducted by aerial spectral images taken by the UAV. To figure out connection, the Pearson’s correlation test was applied to analyze the correlation between factors. These research results show that the NDVI/NDRE in WS and SA crops increased and decreased steadily after reaching the maximum values (0.85 ± 0.02/ 0.38 ± 0.02 and 0.8 ± 0.02/ 0.28 ± 0.02) during the reproductive stage. The NDVI/NDRE had a high relationship with the plant height, tiller number, yield components of rice. WS and SA networks were built and tested according to the training algorithm in the Matlab software for predicting rice yield with high reliability. The developed models showcase promising results in forecasting rice yield, underscoring the potential applicability of this methodology in agricultural yield prediction.