bluuebunny/crossref_metadata_2025 huggingface dataset:
A Low-Rate Video Approach to Hyperspectral Imaging of Dynamic Scenes
Authors: Bachmann Charles M. , Eon Rehman S. , Lapszynski Christopher S. , Badura Gregory P. , Vodacek Anthony , Hoffman Matthew J. , McKeown Donald , Kremens Robert L. , Richardson Michael , Bauch Timothy , Foote Mark
Published: December 2018

The increased sensitivity of modern hyperspectral line-scanning systems has led to the development of imaging systems that can acquire each line of hyperspectral pixels at very high data rates (in the 200–400 Hz range). These data acquisition rates present an opportunity to acquire full hyperspectral scenes at rapid rates, enabling the use of traditional push-broom imaging systems as low-rate video hyperspectral imaging systems. This paper provides an overview of the design of an integrated system that produces low-rate video hyperspectral image sequences by merging a hyperspectral line scanner, operating in the visible and near infra-red, with a high-speed pan-tilt system and an integrated IMU-GPS that provides system pointing. The integrated unit is operated from atop a telescopic mast, which also allows imaging of the same surface area or objects from multiple view zenith directions, useful for bi-directional reflectance data acquisition and analysis. The telescopic mast platform also enables stereo hyperspectral image acquisition, and therefore, the ability to construct a digital elevation model of the surface. Imaging near the shoreline in a coastal setting, we provide an example of hyperspectral imagery time series acquired during a field experiment in July 2017 with our integrated system, which produced hyperspectral image sequences with 371 spectral bands, spatial dimensions of 1600 × 212, and 16 bits per pixel, every 0.67 s. A second example times series acquired during a rooftop experiment conducted on the Rochester Institute of Technology campus in August 2017 illustrates a second application, moving vehicle imaging, with 371 spectral bands, 16 bit dynamic range, and 1600 × 300 spatial dimensions every second.
A Control Method for the Ultrasonic Spot Welding of Fiber-Reinforced Thermoplastic Laminates through the Weld-Power Time Derivative
Authors: Tutunjian Shahan , Dannemann Martin , Fischer Fabian , Eroğlu Oğuzhan , Modler Niels
Published: December 2018

It was found that the ultrasonic spot welding may serve as an efficient method to join relative large thin-walled parts made of fiber-reinforced thermoplastics. In this study, a new control method for the ultrasonic spot-welding process was investigated. It was found that, when welding fiber-reinforced thermoplastic laminates without energy directors, overheating and decomposition of the polymer at the weld spot occurred. The occurrence of the overheating took place at unpredictable times during welding. It was observed that the time trace of the consumed power curve by the welder follows a similar pattern as the time trace of the temperature in the weld spot center. Based on this observation, a control system was developed. The time derivative of the welder power was monitored in real time and, as soon as it exceeded a critical value, the ultrasonic vibration amplitude was actively adjusted through a microcontroller. The controlling of the ultrasonic welding process forced the temperature in the weld spot to remain in an adequate range throughout the welding duration for the polymer diffusion to occur. The results of the controlled welding process were evaluated by means of weld temperature measurements, computed tomography scans, and microscopic analysis of the weld spot fracture surfaces.
Re-Placing the Desert in the Conservation Landscape: Charisma and Absence in the Gobi Desert
Authors: Lezak Stephen
Published: December 2018

Across the Gobi Desert in China and Mongolia, millions of newly planted trees struggle to survive amid adverse ecological conditions. They were planted by a wide variety of actors in an attempt to protect, restore, or modify the local environment, despite evidence of their negative consequences upon local ecosystems. This paper investigates how these afforestation projects both challenge and affirm recent theoretical work on conservation, while also providing key insights into the decision-making framework of land management across the world’s third largest desert region. This analysis, supported by evidence from corporate practice, government policy, and participant observation, builds primarily on the work of Jamie Lorimer and other authors who identify the charisma of certain species as a primary driver of contemporary conservation. But the case of afforestation in the Gobi is inadequately explained by a desire to protect individual species; rather, I show how the charisma at the level of the landscape influences conservation practice. I extend this analysis to suggest that the management of deserts worldwide may be mediated by their perception as absent or empty spaces, thus explaining projects like afforestation which seem to re-place rather than conserve. Using the framework of absence and presence to better understand land use and environmental governance could have implications extending well beyond the Gobi Desert.
Roll-to-Roll Manufacturing of Micropatterned Adhesives by Template Compression
Authors: Yu Dan , Beckelmann Dirk , Opsölder Michael , Schäfer Bruno , Moh Karsten , Hensel René , De Oliveira Peter William , Arzt Eduard
Published: December 2018

For the next generation of handling systems, reversible adhesion enabled by micropatterned dry adhesives exhibits high potential. The versatility of polymeric micropatterns in handling objects made from various materials has been demonstrated by several groups. However, specimens reported in most studies have been restricted to the laboratory scale. Upscaling the size and quantity of micropatterned adhesives is the next step to enable successful technology transfer. Towards this aim, we introduce a continuous roll-to-roll replication process for fabrication of high-performance, mushroom-shaped micropatterned dry adhesives. The micropatterns were made from UV-curable polyurethane acrylates. To ensure the integrity of the complex structure during the fabrication process, flexible templates were used. The compression between the template and the wet prepolymer coating was investigated to optimize replication results without structural failures, and hence, to improve adhesion. As a result, we obtained micropatterned adhesive tapes, 10 cm in width and several meters in length, with adhesion strength about 250 kPa to glass, suitable for a wide range of applications.
Effect of Defects on Spontaneous Polarization in Pure and Doped LiNbO3: First-Principles Calculations
Authors: Wang Weiwei , Zheng Dahuai , Hu Mengyuan , Saeed Shahzad , Liu Hongde , Kong Yongfa , Zhang Lixin , Xu Jingjun
Published: December 2018

Numerous studies have indicated that intrinsic defects in lithium niobate (LN) dominate its physical properties. In an Nb-rich environment, the structure that consists of a niobium anti-site with four lithium vacancies is considered the most stable structure. Based on the density functional theory (DFT), the specific configuration of the four lithium vacancies of LN were explored. The results indicated the most stable structure consisted of two lithium vacancies as the first neighbors and the other two as the second nearest neighbors of Nb anti-site in pure LN, and a similar stable structure was found in the doped LN. We found that the defects dipole moment has no direct contribution to the crystal polarization. Spontaneous polarization is more likely due to the lattice distortion of the crystal. This was verified in the defects structure of Mg2+, Sc3+, and Zr4+ doped LN. The conclusion provides a new understanding about the relationship between defect clusters and crystal polarization.
Analysis of Failure Mechanics in Hybrid Fibre-Reinforced High-Performance Concrete Deep Beams with and without Openings
Authors: Smarzewski Piotr
Published: December 2018

The article presents the results of experimental- and analytical investigations of the behaviour and the load-carrying capacity of deep beams with openings (DBO) and without openings (DB) made of hybrid steel-polypropylene fibre-reinforced high-performance concrete (HFRHPC) subjected to three-point bending tests. Six deep beams 100 mm × 500 mm × 1000 mm were tested with a gradually increasing load until failure. All the specimens were tested in the same simply supported conditions. The research focused on the quantity and kind of concrete reinforcement. The deep beams with steel and polypropylene (PP) fibres were characterised by variously arranged steel bar reinforcement: vertically, horizontally, orthogonally and diagonally. The DB1, DBO1 deep beams were conventionally made with steel rod reinforcement but without fibres. The steel wire mesh reinforcement was replaced by fibre reinforcement of varying volume percentages in the remaining deep beams. The influence of the hybrid fibre content in the specimens was studied by marking the development and propagation of cracks, by recording the failure modes, and by monitoring the deflections at the bottom of the deep beam, at the mid-span and at the support. Three-dimensional measurements of strain and displacement of the deep beams without openings (DB) were performed by the non-contact optical 3D deformation measuring system ARAMIS. The experimental results were compared with the studied methods of predicting the shear strength of deep beams reinforced with hybrid fibre. The conducted study demonstrates that hybrid fibres as web reinforcement have a favourable impact on deep beam crack widths and raise the load carrying capacity of deep beams with openings.
Light Concentration by Metal-Dielectric Micro-Resonators for SERS Sensing
Authors: Sarychev Andrey K. , Ivanov Andrey , Lagarkov Andrey , Barbillon Grégory
Published: December 2018

Metal-dielectric micro/nano-composites have surface plasmon resonances in visible and near-infrared domains. Excitation of coupled metal-dielectric resonances is also important. These different resonances can allow enhancement of the electromagnetic field at a subwavelength scale. Hybrid plasmonic structures act as optical antennae by concentrating large electromagnetic energy in micro- and nano-scales. Plasmonic structures are proposed for various applications such as optical filters, investigation of quantum electrodynamics effects, solar energy concentration, magnetic recording, nanolasing, medical imaging and biodetection, surface-enhanced Raman scattering (SERS), and optical super-resolution microscopy. We present the review of recent achievements in experimental and theoretical studies of metal-dielectric micro and nano antennae that are important for fundamental and applied research. The main impact is application of metal-dielectric optical antennae for the efficient SERS sensing.
Hexagonal Boron Nitride/Microfibril Cellulose/Poly(vinyl alcohol) Ternary Composite Film with Thermal Conductivity and Flexibility
Authors: Ge Xin , Liang Wei-Jie , Ge Jian-Fang , Chen Xun-Jun , Ji Jian-Ye , Pang Xiao-Yan , He Ming , Feng Xiao-Meng
Published: December 2018

Microfibril cellulose (MFC), which is detrimental to soil cultivation and environmental protection, is derived from waste pineapple leaves. Hexagonal boron nitride (h-BN) was modified with polydopamine (PDA)—PDA@h-BN named pBN, and then combined with MFC to prepare a novel hybrid powder. The effect of PDA on h-BN and the binding effect between pBN and MFC were characterized by X-ray photoelectron spectroscopy (XPS), Thermogravimetric (TG), scanning electron microscopy (SEM), and Fourier Transform-Infrared (FT-IR). Poly (vinyl alcohol) (PVA) was used as an eco-friendly polymeric matrix to prepare a pBN-MFC-PVA composite film. The mechanical strength, hydrophobicity, and thermal conductivity of the film were studied and the results confirmed that h-BN was chemically modified with PDA and was uniformly distributed along the MFC. The thermal conductivity of the pBN-MFC-PVA composite film increased with the addition of a pBN-MFC novel powder. MFC acted as “guides” to mitigate the h-BN agglomerate. In addition to the possible usage in the pBN-MFC-PVA composite film itself, the pBN-MFC hybrid powder may be a potential filler candidate for manufacturing thermal interface materials and wearable devices or protective materials.
Role of Wood Fibers in Tuning Dynamic Rheology, Non-Isothermal Crystallization, and Microcellular Structure of Polypropylene Foams
Authors: Song Yongming , Wang Youyong , Li Hao , Zong Qiling , Xu Ailing
Published: December 2018

Microcellular polypropylene (PP)/wood fiber composite foams were fabricated via batch foaming assisted by supercritical CO2 (scCO2). Effects of wood fibers on rheology, crystallization, and foaming behaviors of PP were comprehensively investigated. The obtained results showed that the incorporation of wood fibers increased the complex viscosity and the storage modulus of the PP matrix. Jeziorny’s model for non-isothermal crystallization kinetics indicated that wood fibers did not change the crystal growth. However, the crystallization rate of the PP matrix was decreased to a certain extent with increasing wood fiber loadings. The wood fiber exerts a noticeable role in improving the cell density and reducing the cell size, despite decreasing the expansion ratio. Interestingly, a “small-sized cells to large-sized cells” gradient cell structure was found around the wood fibers, implying cell nucleation was induced at the interface between wood fiber and PP matrix. When wood fiber loadings were specifically increased, a desirable microcellular structure was obtained. However, further increasing the wood fiber loadings deteriorated the cell structure. Moreover, the crystallinity of the composite foams initially decreased and then slightly increased with increasing wood fiber loadings, while the crystal size decreased.
Non Monotonous Effects of Noncovalently Functionalized Graphene Addition on the Structure and Sound Absorption Properties of Polyvinylpyrrolidone (1300 kDa) Electrospun Mats
Authors: Del Sorbo Giuseppe Rosario , Truda Greta , Bifulco Aurelio , Passaro Jessica , Petrone Giuseppe , Vitolo Bonaventura , Ausanio Giovanni , Vergara Alessandro , Marulo Francesco , Branda Francesco
Published: December 2018

Graphene is an attractive component for high-performance stimuli-responsive or ‘smart’ materials, shape memory materials, photomechanical actuators, piezoelectric materials and flexible strain sensors. Nanocomposite fibres were produced by electrospinning high molecular weight Polyvinylpyrrolidone (PVP-1300 kDa) in the presence of noncovalently functionalised graphene obtained through tip sonication of graphite alcoholic suspensions in the presence of PVP (10 kDa). Bending instability of electrospun jet appears to progressively increase at low graphene concentrations with the result of greater fibre stretching that leads to lower fibre diameter and possibly conformational changes of PVP. Further increase of graphene content seams having the opposite effect leading to greater fibre diameter and Raman spectra similar to the pure PVP electrospun mats. All this has been interpreted on the basis of currently accepted model for bending instability of electrospun jets. The graphene addition does not lower the very high sound absorption coefficient, α, close to unity, of the electrospun PVP mats in the frequency range 200–800 Hz. The graphene addition affects, in a non-monotonous manner, the bell shaped curves of α versus frequency curves becoming sharper and moving to higher frequency at the lower graphene addition. The opposite is observed when the graphene content is further increased.
Preparation of Textured Surfaces on Aluminum-Alloy Substrates
Authors: Kadlečková Markéta , Minařík Antonín , Smolka Petr , Mráček Aleš , Wrzecionko Erik , Novák Libor , Musilová Lenka , Gajdošík Radek
Published: December 2018

The ways of producing porous-like textured surfaces with chemical etching on aluminum-alloy substrates were studied. The most appropriate etchants, their combination, temperature, and etching time period were explored. The influence of a specifically textured surface on adhesive joints’ strength or superhydrophobic properties was evaluated. The samples were examined with scanning electron microscopy, profilometry, atomic force microscopy, goniometry, and tensile testing. It was found that, with the multistep etching process, the substrate can be effectively modified and textured to the same morphology, regardless of the initial surface roughness. By selecting proper etchants and their sequence one can prepare new types of highly adhesive or even superhydrophobic surfaces.
Current-Induced Ductility Enhancement of a Magnesium Alloy AZ31 in Uniaxial Micro-Tension Below 373 K
Authors: Wang Xinwei , Sánchez Egea Antonio J. , Xu Jie , Meng Xianyu , Wang Zhenlong , Shan Debin , Guo Bin , Cao Jian
Published: December 2018

The size effects in metal forming have been found to be crucial in micro-scale plastic deformation or micro-forming processes, which lead to attenuation of the material’s formability due to the increasing heterogeneity of the plastic flow. The use of an electric field during micro-scale plastic deformation has shown to relieve size effects, enhance the material’s formability, modify the microstructure, etc. Consequently, these electric-assisted (EA) micro-forming processes seem to bring many potential benefits that need to be investigated. Accordingly, here we investigated the influence of an electric field on the size effects to describe the fracture behavior in uniaxial micro-tension tests of an AZ31 alloy with various grain sizes. In order to decouple the thermal-mechanical and microstructure changes, room temperature (RT), oven-heated (OH), air-cooled (AC), and EA uniaxial micro-tension tests were conducted. The size effects contribution on the fracture stress and strain showed a similar trend in all the testing configurations. However, the smallest fracture stresses and the largest fracture strains were denoted in the EA configuration. EBSD examination shows that current-induced dynamic recrystallization (DRX) and texture evolution could be negligible under the studied conditions. The kernel average misorientation (KAM) maps give the larger plastic deformation in the EA specimens due to the reduction of plastic micro-heterogeneity. Finally, the fracture morphology indicates that the current-induced ductility enhancement may be attributed to the arrest of micro-crack propagation and the inhibition of void initiation, growth, and coalescence caused by lattice melting and expansion.
Effect of Recrystallization Annealing on Corrosion Behavior of Ta-4%W Alloy
Authors: Ma Guoqiang , He Qiongyao , Luo Xuan , Wu Guilin , Chen Qiang
Published: December 2018

The effect of recrystallization annealing on corrosion behavior of Ta-4%W alloy was studied. It is found that the deformed sample contains high dense dislocations and dislocation boundaries. During annealing, these dislocations and dislocation boundaries are replaced by recrystallizing grains until the alloy is fully recrystallized. Both the anodic dissolution and the cathodic activity is much more blocked. The corrosion potential gradual shift towards negative values and corrosion current density decrease, while polarization resistance increases after annealing, indicating enhanced corrosion resistance of the alloy. Such an enhancement is caused by the increase of low-Σ coincide site lattice boundaries and decrease of dislocations and dislocation boundaries.
A Reversible Protonic Ceramic Cell with Symmetrically Designed Pr2NiO4+δ-Based Electrodes: Fabrication and Electrochemical Features
Authors: Tarutin Artem , Lyagaeva Julia , Farlenkov Andrey , Plaksin Sergey , Vdovin Gennady , Demin Anatoly , Medvedev Dmitry
Published: December 2018

Reversible protonic ceramic cells (rPCCs) combine two different operation regimes, fuel cell and electrolysis cell modes, which allow reversible chemical-to-electrical energy conversion at reduced temperatures with high efficiency and performance. Here we present novel technological and materials science approaches, enabling a rPCC with symmetrical functional electrodes to be prepared using a single sintering step. The response of the cell fabricated on the basis of P–N–BCZD|BCZD|PBN–BCZD (where BCZD = BaCe0.5Zr0.3Dy0.2O3−δ, PBN = Pr1.9Ba0.1NiO4+δ, P = Pr2O3, N = Ni) is studied at different temperatures and water vapor partial pressures (pH2O) by means of volt-ampere measurements, electrochemical impedance spectroscopy and distribution of relaxation times analyses. The obtained results demonstrate that symmetrical electrodes exhibit classical mixed-ionic/electronic conducting behavior with no hydration capability at 750 °C; therefore, increasing the pH2O values in both reducing and oxidizing atmospheres leads to some deterioration of their electrochemical activity. At the same time, the electrolytic properties of the BCZD membrane are improved, positively affecting the rPCC’s efficiency. The electrolysis cell mode of the rPCC is found to be more appropriate than the fuel cell mode under highly humidified atmospheres, since its improved performance is determined by the ohmic resistance, which decreases with pH2O increasing.
Convergence Ball and Complex Geometry of an Iteration Function of Higher Order
Authors: Kumar Deepak , Argyros Ioannis K. , Sharma Janak Raj
Published: December 2018

Higher-order derivatives are used to determine the convergence order of iterative methods. However, such derivatives are not present in the formulas. Therefore, the assumptions on the higher-order derivatives of the function restrict the applicability of methods. Our convergence analysis of an eighth-order method uses only the derivative of order one. The convergence results so obtained are applied to some real problems, which arise in science and engineering. Finally, stability of the method is checked through complex geometry shown by drawing basins of attraction of the solutions.
Use of Enumerative Combinatorics for Proving the Applicability of an Asymptotic Stability Result on Discrete-Time SIS Epidemics in Complex Networks
Authors: Rodríguez Lucatero Carlos , Alarcón Ramos Luis Angel
Published: December 2018

In this paper, we justify by the use of Enumerative Combinatorics, the applicability of an asymptotic stability result on Discrete-Time Epidemics in Complex Networks, where the complex dynamics of an epidemic model to identify the nodes that contribute the most to the propagation process are analyzed, and, because of that, are good candidates to be controlled in the network in order to stabilize the network to reach the extinction state. The epidemic model analyzed was proposed and published in 2011 by of Gómez et al. The asymptotic stability result obtained in the present article imply that it is not necessary to control all nodes, but only a minimal set of nodes if the topology of the network is not regular. This result could be important in the spirit of considering policies of isolation or quarantine of those nodes to be controlled. Simulation results using a refined version of the asymptotic stability result were presented in another paper of the second author for large free-scale and regular networks that corroborate the theoretical findings. In the present article, we justify the applicability of the controllability result obtained in the mentioned paper in almost all the cases by means of the use of Combinatorics.
Accurate and Efficient Explicit Approximations of the Colebrook Flow Friction Equation Based on the Wright ω-Function
Authors: Brkić Dejan , Praks Pavel
Published: December 2018

The Colebrook equation is a popular model for estimating friction loss coefficients in water and gas pipes. The model is implicit in the unknown flow friction factor, f . To date, the captured flow friction factor, f , can be extracted from the logarithmic form analytically only in the term of the Lambert W -function. The purpose of this study is to find an accurate and computationally efficient solution based on the shifted Lambert W -function also known as the Wright ω-function. The Wright ω-function is more suitable because it overcomes the problem with the overflow error by switching the fast growing term, y = W ( e x ) , of the Lambert W -function to series expansions that further can be easily evaluated in computers without causing overflow run-time errors. Although the Colebrook equation transformed through the Lambert W -function is identical to the original expression in terms of accuracy, a further evaluation of the Lambert W -function can be only approximate. Very accurate explicit approximations of the Colebrook equation that contain only one or two logarithms are shown. The final result is an accurate explicit approximation of the Colebrook equation with a relative error of no more than 0.0096%. The presented approximations are in a form suitable for everyday engineering use, and are both accurate and computationally efficient.
The Jellyfish Rhizostoma pulmo (Cnidaria): Biochemical Composition of Ovaries and Antibacterial Lysozyme-like Activity of the Oocyte Lysate
Authors: Stabili Loredana , Rizzo Lucia , Fanizzi Francesco Paolo , Angilè Federica , Del Coco Laura , Girelli Chiara Roberta , Lomartire Silvia , Piraino Stefano , Basso Lorena
Published: December 2018

Jellyfish outbreaks in marine coastal areas represent an emergent problem worldwide, with negative consequences on human activities and ecosystem functioning. However, potential positive effects of jellyfish biomass proliferation may be envisaged as a natural source of bioactive compounds of pharmaceutical interest. We investigated the biochemical composition of mature female gonads and lysozyme antibacterial activity of oocytes in the Mediterranean barrel jellyfish Rhizostoma pulmo. Chemical characterization was performed by means of multinuclear and multidimensional NMR spectroscopy. The ovaries of R. pulmo were mainly composed of water (93.7 ± 1.9% of wet weight), with organic matter (OM) and dry weight made respectively of proteins (761.76 ± 25.11 µg mg−1 and 45.7 ± 1.5%), lipids (192.17 ± 10.56 µg mg−1 and 9.6 ± 0.6%), and carbohydrates (59.66 ± 2.72 µg mg−1 and 3.7 ± 0.3%). The aqueous extract of R. pulmo gonads contained free amino acids, organic acids, and derivatives; the lipid extract was composed of triglycerides (TG), polyunsaturated fatty acids (PUFAs), diunsaturated fatty acids (DUFAs), monounsaturated fatty acids (MUFAs), saturated fatty acids (SFAs), and minor components such as sterols and phospholipids. The R. pulmo oocyte lysate exhibited an antibacterial lysozyme-like activity (mean diameter of lysis of 9.33 ± 0.32 mm corresponding to 1.21 mg/mL of hen egg-white lysozyme). The occurrence of defense molecules is a crucial mechanism to grant healthy development of mature eggs and fertilized embryos (and the reproductive success of the species) by preventing marine bacterial overgrowth. As a corollary, these results call for future investigations for an exploitation of R. pulmo biomasses as a resource of bioactive metabolites of biotechnological importance including pharmaceuticals and nutrition.
An Unprecedented Medium-Chain Diunsaturated N-acylhomoserine Lactone from Marine Roseobacter Group Bacteria
Authors: Ziesche Lisa , Wolter Laura , Wang Hui , Brinkhoff Thorsten , Pohlner Marion , Engelen Bert , Wagner-Döbler Irene , Schulz Stefan
Published: December 2018

N-acylhomoserine lactones (AHLs), bacterial signaling compounds involved in quorum-sensing, are a structurally diverse group of compounds. We describe here the identification, synthesis, occurrence and biological activity of a new AHL, N-((2E,5Z)-2,5-dodecadienoyl)homoserine lactone (11) and its isomer N-((3E,5Z)-3,5-dodecadienoyl)homoserine lactone (13), occurring in several Roseobacter group bacteria (Rhodobacteraceae). The analysis of 26 strains revealed the presence of 11 and 13 in six of them originating from the surface of the macroalgae Fucus spiralis or sediments from the North Sea. In addition, 18 other AHLs were detected in 12 strains. Compound identification was performed by GC/MS. Mass spectral analysis revealed a diunsaturated C12 homoserine lactone as structural element of the new AHL. Synthesis of three likely candidate compounds, 11, 13 and N-((2E,4E)-2,4-dodecadienoyl)homoserine lactone (5), revealed the former to be the natural AHLs. Bioactivity test with quorum-sensing reporter strains showed high activity of all three compounds. Therefore, the configuration and stereochemistry of the double bonds in the acyl chain seemed to be unimportant for the activity, although the chains have largely different shapes, solely the chain length determining activity. In combination with previous results with other Roseobacter group bacteria, we could show that there is wide variance between AHL composition within the strains. Furthermore, no association of certain AHLs with different habitats like macroalgal surfaces or sediment could be detected.
Drug-Loaded Biocompatible Nanocarriers Embedded in Poloxamer 407 Hydrogels as Therapeutic Formulations
Authors: Giuliano Elena , Paolino Donatella , Fresta Massimo , Cosco Donato
Published: December 2018

Hydrogels are three-dimensional networks of hydrophilic polymers able to absorb and retain a considerable amount of water or biological fluid while maintaining their structure. Among these, thermo-sensitive hydrogels, characterized by a temperature-dependent sol–gel transition, have been massively used as drug delivery systems for the controlled release of various bioactives. Poloxamer 407 (P407) is an ABA-type triblock copolymer with a center block of hydrophobic polypropylene oxide (PPO) between two hydrophilic polyethyleneoxide (PEO) lateral chains. Due to its unique thermo-reversible gelation properties, P407 has been widely investigated as a temperature-responsive material. The gelation phenomenon of P407 aqueous solutions is reversible and characterized by a sol–gel transition temperature. The nanoencapsulation of drugs within biocompatible delivery systems dispersed in P407 hydrogels is a strategy used to increase the local residence time of various bioactives at the injection site. In this mini-review, the state of the art of the most important mixed systems made up of colloidal carriers localized within a P407 hydrogel will be provided in order to illustrate the possibility of obtaining a controlled release of the entrapped drugs and an increase in their therapeutic efficacy as a function of the biomaterial used.
Cylindrical Free-Standing Mode Triboelectric Generator for Suspension System in Vehicle
Authors: Kang Minki , Kim Tae , Seung Wanchul , Han Jae-Hee , Kim Sang-Woo
Published: December 2018

The triboelectric generator (TEG) is a strong candidate for low-power sensors utilized in the Internet of Things (IoT) technology. Within IoT technologies, advanced driver assistance system (ADAS) technology is included within autonomous driving technology. Development of an energy source for sensors necessary for operation becomes an important issue, since a lot of sensors are embedded in vehicles and require more electrical energy. Although saving energy and enhancing energy efficiency is one of the most important issues, the application approach to harvesting wasted energy without compromising the reliability of existing mechanical systems is still in very early stages. Here, we report of a new type of TEG, a suspension-type free-standing mode TEG (STEG) inspired from a shock absorber in a suspension system. We discovered that the optimum width of electrode output voltage was 131.9 V and current was 0.060 µA/cm2 in root mean square (RMS) value while the optimized output power was 4.90 μW/cm2 at 66 MΩ. In addition, output power was found to be proportional to frictional force due to the contact area between two frictional surfaces. It was found that the STEG was made of perfluoroalkoxy film and showed good mechanical durability with no degradation of output performance after sliding 11,000 times. In addition, we successfully demonstrated charging a capacitor of 330 μF in 6 min.
Research of a Novel 3D Printed Strain Gauge Type Force Sensor
Authors: Liu Mingjie , Zhang Qi , Shao Yiwei , Liu Chuanqi , Zhao Yulong
Published: December 2018

A 3D printed force sensor with a composite structure developed by combining digital light processing (DLP) based printing and inkjet printing technologies is described in this paper. The sensor has cost effectiveness and time-saving advantages compared to the traditional sensor manufacturing process. During this work, the substrate of the force sensor was printed by a DLP based 3D printer using a transparent high-temperature resin, and the strain gauge of the force sensor was inkjet printed using poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT/PSS) conductive ink. Finite element (FE) simulation was conducted to find the print origin of the strain gauge. The relationship between the mechanical properties of the post-cured resin and the curing time was investigated and the resistance of the printed strain gauges was characterized to optimize process parameters. Afterward, the force sensor was characterized. Experimental results show that the sensitivity of the sensor is 2.92% N−1 and the linearity error is 3.1485% full scale (FS) within the range from 0 mN–160 mN, and the effective gauge factor of the strain gauge is about 0.98. The resistance drifting is less than 0.004 kΩ within an hour. These figures prove that the device can perform as a force sensor and 3D printing technology may have great applied potential in sensor fabrication.
Technological Assessment of MEMS Alkali Vapor Cells for Atomic References
Authors: Knapkiewicz Pawel
Published: December 2018

This paper is a review that surveys work on the fabrication of miniature alkali vapor cells for miniature and chip-scale atomic clocks. Technology on microelectromechanical systems (MEMS) cells from the literature is described in detail. Special attention is paid to alkali atom introduction methods and sealing of the MEMS structure. Characteristics of each technology are collated and compared. The article’s rhetoric is guided by the proposed classification of MEMS cell fabrication methods and contains a historical outline of MEMS cell technology development.
Comparative Study on Shale Characteristics of Different Sedimentary Microfacies of Late Permian Longtan Formation in Southwestern Guizhou, China
Authors: Ma Xiao , Guo Shaobin
Published: December 2018

Organic-rich marine-continental transitional shales are widely distributed in Guizhou Province, China. Samples from the Late Permian Longtan Formation were investigated using organic petrography analysis, X-ray diffraction (XRD) analysis, field emission-scanning electron microscopy observations, mercury intrusion capillary pressure and gas adsorption experiments to better understand the organic geochemical characteristic, mineralogical composition, full-size pore structure characteristics and fractal characteristic of shale reservoir. The relationships among the total organic carbon (TOC) content, mineral composition, pore structure parameter, methane adsorption capacity and fractal dimension of shale samples are discussed, along with the differences between different sedimentary microfacies. Results show that shale samples are characterized by high TOC contents, low permeability, complex mineral composition and pore structure. Shales of YV-1, deposited in delta and lower delta plains, have an extreme high clay content (71.33% average) and the clay minerals mainly consist of the I/S and kaolinite, while shales of XD-1, deposited in the lagoon-tidal flat, have a relatively low clay content (37% average) and the I/S occupies an absolute advantage. The pore volume, specific surface area and average pore diameter of YV-1 (0.02881 cm3/g, 20.806 m2/g and 11.07 nm, respectively) are larger than that of XD-1 (0.02110 cm3/g, 20.101 m2/g, and 8.40 nm, respectively). The mesopore of YV-1 is the predominant contributor to the pore structure, while the micropore of XD-1 also occupies a certain proportion in addition to the mesopore. Organic matter (OM)-hosted pores are largely developed in XD-1 samples, while clay mineral-hosted pores dominate the pore system of YV-1. Shale samples with higher TOC content and clay content generally have larger specific surface area and pore volume, which provides more adsorption space and enhances pore structure heterogeneity. Samples of XD-1 have high TOC contents, suitable mineral composition and complex pore structure, suggesting that shales deposited in a lagoon-tidal flat environment may have a greater potential for shale gas development.
Influence of Piracetam on Gliclazide—Glycated Human Serum Albumin Interaction. A Spectrofluorometric Study
Authors: Szkudlarek Agnieszka , Pożycka Jadwiga , Maciążek-Jurczyk Małgorzata
Published: December 2018

Advanced Glycation End-Products (AGEs) are created in the last step of protein glycation and can be a factor in aging and in the development or worsening of many degenerative diseases (diabetes, chronic kidney disease, atherosclerosis, Alzheimer’s disease, etc.). Albumin is the most susceptible to glycation plasma protein. Modified albumin by AGEs may be more resistant to enzymatic degradation, which further increases the local accumulation of AGEs in tissues. The aim of the present study was to analyze in vitro glycation of serum albumin in the presence of piracetam (PIR) and the gliclazide (GLZ)-glycated albumin interaction. The analysis of PIR as an inhibitor and GLZ interaction with nonglycated human albumin (HSA) and glycated by fructose human albumin (gHSAFRC), in the absence and presence of piracetam (gHSAFRC-PIR), was performed by fluorescence quenching of macromolecules. On the basis of obtained data we concluded that under the influence of glycation, association constant ( K a ) of gliclazide to human serum albumin decreases and GLZ binds to HSA with less strength than under physiological conditions. PIR strongly inhibited the formation of AGEs in the system where the efficiency of HSA glycation was the largest. The analysis of piracetam influence on the GLZ-glycated albumin interaction has shown that piracetam increases the binding strength of GLZ to glycated albumin and weakens its therapeutic effect. Based on the obtained data we concluded that monitoring therapy and precautions are required in the treatment when the combinations of gliclazide and piracetam are used at the same time.
Simultaneous Optimization for Ultrasound-Assisted Extraction and Antioxidant Activity of Flavonoids from Sophora flavescens Using Response Surface Methodology
Authors: Zhou Jing , Zhang Lincheng , Li Qinping , Jin Weifeng , Chen Weiyan , Han Jin , Zhang Yuyan
Published: December 2018

The ultrasonic-assisted extraction process and antioxidant activity of flavonoids from Sophora flavescens were investigated in this study. In order to optimize the extraction of flavonoids from Sophora flavescens, the influence of extraction time, methanol concentration, ultrasonic temperature, and solvent-to-material ratio was analyzed. Results showed that the extraction yields reached a maximum with the extraction time of 30 min, methanol concentration of 80%, temperature of 80 °C, and solvent-to-material ratio of 26 mL/g. The flavonoids were determined by HPLC, and the mean yields of trifolirhizin, formononetin, isoxanthohumol, maackiain, and kurarinone under the optimal conditions were 2.570, 0.213, 0.534, 0.797, and 3.091 mg/g, respectively. The evaluation of vitro antioxidant activity exhibited Sophora flavescens flavonoids had a strong 1,1-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radical-scavenging ability with IC50 of 0.984 and 1.084 mg/g, respectively. These results indicate that ultrasonic-assisted extraction is an efficient approach for the selective extraction of flavonoids, and response surface methodology further optimized the extraction.
PPARα Agonist Suppresses Inflammation after Corneal Alkali Burn by Suppressing Proinflammatory Cytokines, MCP-1, and Nuclear Translocation of NF-κB
Authors: Nakano Yuichiro , Uchiyama Masaaki , Arima Takeshi , Nagasaka Shinya , Igarashi Tsutomu , Shimizu Akira , Takahashi Hiroshi
Published: December 2018

We investigated the effect of a peroxisome proliferator-activated receptor α (PPARα) agonist after corneal alkali injury. Fenofibrate 0.05% (PPARα agonist group) or vehicle (Vehicle group) was topically instilled onto the rat cornea after injury. Histological, immunohistochemical, and real-time reverse transcription PCR analyses were performed. PPARα-positive cells were observed among basal cells of the corneal epithelium in normal and alkali-burned corneas. The number of infiltrating neutrophils and macrophages at the corneal limbus was lower in the PPARα agonist group. Interleukin-1β (IL-1β), IL-6, IL-8, monocyte chemoattractant protein-1 (MCP-1), and vascular endothelial growth factor-An mRNA expression was suppressed in the PPARα agonist group compared to the Vehicle group. mRNA levels of nuclear factor kappa B (NF-κB) in corneal tissue were not different. However, NF-κB was expressed in the cytoplasm of basal cells in the PPARα agonist group and in the nucleus in the Vehicle group. MCP-1 was more weakly expressed in the PPARα agonist group. The PPARα agonist inhibited inflammation during the early phase after injury. Anti-inflammatory effects of the PPARα agonist included prevention of up-regulation of proinflammatory cytokines and MCP-1, and prevention of inflammatory cell infiltration into the injured cornea. Thus, a PPARα agonist may be a promising treatment for corneal injury.
Nanographene and Graphene Nanoribbon Synthesis via Alkyne Benzannulations
Authors: Senese Amber D. , Chalifoux Wesley A.
Published: December 2018

The extension of π-conjugation of polycyclic aromatic hydrocarbons (PAHs) via alkyne benzannulation reactions has become an increasingly utilized tool over the past few years. This short review will highlight recent work of alkyne benzannulations in the context of large nanographene as well as graphene nanoribbon synthesis along with a brief discussion of the interesting physical properties these molecules display.
Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities
Authors: Marrelli Mariangela , Amodeo Valentina , Statti Giancarlo , Conforti Filomena
Published: December 2018

Common onion (Allium cepa L.) is one of the oldest cultivated plants, utilized worldwide as both vegetable and flavouring. This species is known to contain sulphur amino acids together with many vitamins and minerals. A variety of secondary metabolites, including flavonoids, phytosterols and saponins, have also been identified. Despite the predominant use of this plant as food, a wide range of beneficial effects have also been proved. Different biological properties, such as antioxidant, antimicrobial and antidiabetic, have been reported. The aim of this review is to provide an overview of the studies concerning the beneficial effects of this species against obesity and its related comorbidities, such as hyperlipidaemia, hypertension and diabetes. Both in vitro and in vivo results about onion dietary supplementation have been taken into account. Furthermore, this review examines the possible role of onion bioactive components in modulating or preventing weight-gain or related diseases, as well as the possible mechanisms behind their activity.
Bioactivity-Guided Purification of Novel Herbal Antioxidant and Anti-NO Compounds from Euonymus laxiflorus Champ.
Authors: Nguyen Van Bon , Wang San-Lang , Nguyen Anh Dzung , Lin Zhi-Hu , Doan Chien Thang , Tran Thi Ngoc , Huang Hung Tse , Kuo Yao-Haur
Published: December 2018

Euonymus laxiflorus Champ., a medicinal herb collected in Vietnam, has been reported to show several potent bioactivities, including anti-NO, enzyme inhibition, hypoglycemic and antidiabetic effects. Recently, the antioxidant activity of Euonymus laxiflorus Champ. trunk bark (ELCTB) has also been reported. However, the active antioxidant and anti-NO constituents existing in ELCTB have not been reported in the literature. The objective of this study was to purify the active antioxidants from ELCTB and investigate the anti-NO effect of the major constituents. Twenty-two phenolics isolated from ELCTB, including 12 compounds newly isolated in this study (1–12) and 10 constituents obtained from our previous work, were evaluated for their antioxidant activity. Of these, 12 compounds (4–6, 9, 13–15, 18–22) showed a potent antioxidant capacity (FRS50 = 7.8–58.11 µg/mL), in comparison to α-tocopherol (FRS50 = 23 µg/mL). In the anti-NO activity tests, Walterolactone A (1a) and B (1b) β-d-glucopyranoside (13) demonstrated the most effective and comparable activity to that of quercetin with max inhibition and IC50 values of 100%, 1.3 µg/mL, and 100%, 1.21 µg/mL, respectively. The crude extract and its major compounds showed no cytotoxicity on normal cells. Notably, three constituents (9, 11, and 12) were identified as new compounds, another three constituents, including 1, 7, and 8, were found to be new natural products, constituents 9 and 13 were determined to be new antioxidants, and compound 13 was reported to have novel potent anti-NO activity for the first time. The results of this study contribute to the enrichment of new natural products and compounds, as well as the novel biological activity of constituents isolated from Euonymus laxiflorus Champ. The current study also indicates ELCTB as a rich natural source of active phenolics. It is suggested that ELCTB could be developed as a health food with promising antioxidant and anti-NO effects, as well as other beneficial biological activities.
Identification and Antioxidant Activity of Flavonoids Extracted from Xinjiang Jujube (Ziziphus jujube Mill.) Leaves with Ultra-High Pressure Extraction Technology
Authors: Zhang Li , Liu Pengzhan , Li Linlin , Huang Ying , Pu Yunfeng , Hou Xujie , Song Lijun
Published: December 2018

In this study, the ultra-high pressure extraction (UHPE) conditions for obtaining the maximum flavonoid yield from Xinjiang jujube (Ziziphus jujuba Mill.) leaves (XJL) were optimized by response surface methodology (RSM). Box–Behnken design (BBD) was applied to evaluate the effects of four variables (extraction temperature, pressure, time and liquid-to-solid ratio) on flavonoid yield. The results showed that the optimal flavonoid yield (25.45 ± 0.21 mg/g) was derived at 50.0 °C, 342.39 MPa, 11.56 min, and a liquid-to-solid ratio of 43.95 mL/g. Eight compounds were tentatively identified and quantified as kaempferol and quercetin glycosides with UPLC-ESI-MS. Compared to ultrasound-assisted extraction (UAE), UHPE can obtain higher concentrations of total flavonoids and stronger DPPH and ABTS radical-scavenging activities in a much shorter time. Therefore, UHPE is an alternative to UAE for obtaining flavonoids from XJL, which may be an optional method for large-scale industrial flavonoid extraction from XJL.