bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of unpaid domestic work in explaining the gender gap in the (monetary) value of leisure
Authors: Jokubauskaitė Simona , Hössinger Reinhard , Jara-Díaz Sergio , Peer Stefanie , Schneebaum Alyssa , Schmid Basil , Aschauer Florian , Gerike Regine , Axhausen Kay W. , Leisch Friedrich
Published: August 2021

The value of travel time savings (VTTS) representing the willingness to pay to reduce travel time, consists of two components: the value of liberating time [equal to the value of leisure (VoL)] and the value of time assigned to travel (VTAT), representing the travel conditions of a trip. Their relative values indicate which dimension to emphasize when investing in transport: speed or comfort. In this paper, we formulate and estimate a framework aimed at the improvement in the estimation of the VoL. By introducing a novel treatment of time assigned to domestic work, we consider that unpaid labor should be assigned a wage rate as a measure of the expenses avoided when assigning time to those chores. We use state-of-the-art data on time use and expenses as well as online data on gig workers collected in Austria, and apply the time-use and expenditure model of Jara-Diaz et al. (Transp Res Part B 42(10):946–957, 2008). The wage rates for paid and unpaid work were combined to re-formulate the budget constraint, which affected women more than men due to the higher involvement of the former in domestic activities. Compared against the original estimation, the VoL changed from €10/h for men and €6/h for women to €9/h for both genders, which in turn yields a larger average VTAT, which becomes positive for public transport. As a conclusion, the novel treatment of domestic labor contributes to closing the gap in the VoL between genders and highlights the power of unveiling the components behind the VTTS. The empirical findings imply that investments in travel time reductions rather than in comfort should be prioritized, given the very good conditions of public transport in Austria.
Strategic reporting by nonprofit hospitals: an examination of bad debt and charity care
Authors: Beck Amanda , Gilstrap Collin , Rippy Jordan , Vansant Brian
Published: August 2021

In this paper, we examine bad debt and charity care reporting by nonprofit hospitals around bond issuance. Given the tax advantages afforded to nonprofit hospitals, including the ability to issue tax-exempt debt, hospital managers encounter stakeholder pressure to provide community benefits. When nonprofits issue debt, they also face economic pressure to meet creditors’ financial performance expectations. We document a reporting strategy that allows nonprofit hospitals to reduce the cost of bond debt while simultaneously alleviating regulators’ and community members’ concerns about inadequate provision of charity care. Using data from public bond issues for California nonprofit hospitals, we find that hospital managers shift costs from bad debt expense to charity care in periods prior to a public bond issuance and that the strategy is associated with a lower cost of debt. Our results inform those relying on accounting measurements to infer nonprofit hospitals’ social good provisions and financial health.
Rheology of Immiscible Two-phase Flow in Mixed Wet Porous Media: Dynamic Pore Network Model and Capillary Fiber Bundle Model Results
Authors: Fyhn Hursanay , Sinha Santanu , Roy Subhadeep , Hansen Alex
Published: August 2021

Immiscible two-phase flow in porous media with mixed wet conditions was examined using a capillary fiber bundle model, which is analytically solvable, and a dynamic pore network model. The mixed wettability was implemented in the models by allowing each tube or link to have a different wetting angle chosen randomly from a given distribution. Both models showed that mixed wettability can have significant influence on the rheology in terms of the dependence of the global volumetric flow rate on the global pressure drop. In the capillary fiber bundle model, for small pressure drops when only a small fraction of the tubes were open, it was found that the volumetric flow rate depended on the excess pressure drop as a power law with an exponent equal to 3/2 or 2 depending on the minimum pressure drop necessary for flow. When all the tubes were open due to a high pressure drop, the volumetric flow rate depended linearly on the pressure drop, independent of the wettability. In the transition region in between where most of the tubes opened, the volumetric flow depended more sensitively on the wetting angle distribution function and was in general not a simple power law. The dynamic pore network model results also showed a linear dependence of the flow rate on the pressure drop when the pressure drop is large. However, out of this limit the dynamic pore network model demonstrated a more complicated behavior that depended on the mixed wettability condition and the saturation. In particular, the exponent relating volumetric flow rate to the excess pressure drop could take on values anywhere between 1.0 and 1.8. The values of the exponent were highest for saturations approaching 0.5, also, the exponent generally increased when the difference in wettability of the two fluids were larger and when this difference was present for a larger fraction of the porous network.
On the Interaction of Viscoelasticity and Waviness in Enhancing the Pull-Off Force in Sphere/Flat Contacts
Authors: Ciavarella Michele , Papangelo Antonio
Published: August 2021

Motivated by roughness-induced adhesion enhancement (toughening and strengthening) in low modulus materials, we study the detachment of a sphere from a substrate in the presence of both viscoelastic dissipation at the contact edge, and roughness in the form of a single axisymmetric waviness. We show that the roughness-induced enhancement found by Guduru and coworkers for the elastic case (i.e. at very small detachment speeds) tends to disappear with increasing speeds, where the viscoelastic effect dominates and the problem approaches that of a smooth sphere. This is in qualitative agreement with the original experiments of Guduru’s group with gelatin. The cross-over velocity is where the two separate effects are comparable. Viscoelasticity effectively damps roughness-induced elastic instabilities and makes their effects much less important.

Graphical Abstract
Assessing the Accuracy of Errors of Measurement. Implications for Assessing Reliable Change in Clinical settings
Authors: Maydeu-Olivares Alberto
Published: August 2021

Item response theory (IRT) models are non-linear latent variable models for discrete measures, whereas factor analysis (FA) is a latent variable model for continuous measures. In FA, the standard error (SE) of individuals’ scores is common for all individuals. In IRT, the SE depends on the individual’s score, and the SE function is to be provided. The empirical standard deviation of the scores across discrete ranges should also be computed to inform the extent to which IRT SEs overestimate or underestimate the variability of the scores. Within the target range of scores the test was designed to measure, one should expect IRT SEs to be smaller and more precise than FA SEs, and therefore preferable to assess clinical change. Outside the target range, IRT SEs may be too large and more imprecise than FA SEs, and FA more precise to assess change. As a result, whether FA or IRT characterize reliable change more accurately in a sample will depend on the proportion of individuals within or outside the IRT target score range. An application is provided to illustrate these concepts.
Surface Enhanced Infrared Characterization Using Disordered Slit-Antenna Arrays for the Detection of Electrodeposited Cytochrome C
Authors: Armelles Gaspar , Cebollada Alfonso , Cava Daniel G. , Alvarez-Malmagro Julia , Vélez Marisela
Published: August 2021

An approach which allows both electrochemical studies and surface enhanced infrared characterization of electrodeposited Cytochrome C is presented. This approach is based on in-plane disordered arrays of resonant slits engraved in Au substrates using focused ion beam. For light-polarized perpendicular to the slit, the reflectivity spectra of the slit arrays show dips related to the excitation of the slit plasmon resonance, whose position depends on the slit length. Due to the presence of the continuous Au layer around the slits, the very same substrates can be used to perform electrochemical studies. By varying the slit length, we have tuned the plasmon resonance to match the absorption bands of electrodeposited Cytochrome C, demonstrating the detection of minute amounts of this protein, all the way down to a single monolayer.
A proof of concept study for machine learning application to stenosis detection
Authors: Jones Gareth , Parr Jim , Nithiarasu Perumal , Pant Sanjay
Published: August 2021

This proof of concept (PoC) assesses the ability of machine learning (ML) classifiers to predict the presence of a stenosis in a three vessel arterial system consisting of the abdominal aorta bifurcating into the two common iliacs. A virtual patient database (VPD) is created using one-dimensional pulse wave propagation model of haemodynamics. Four different machine learning (ML) methods are used to train and test a series of classifiers—both binary and multiclass—to distinguish between healthy and unhealthy virtual patients (VPs) using different combinations of pressure and flow-rate measurements. It is found that the ML classifiers achieve specificities larger than 80% and sensitivities ranging from 50 to 75%. The most balanced classifier also achieves an area under the receiver operative characteristic curve of 0.75, outperforming approximately 20 methods used in clinical practice, and thus placing the method as moderately accurate. Other important observations from this study are that (i) few measurements can provide similar classification accuracies compared to the case when more/all the measurements are used; (ii) some measurements are more informative than others for classification; and (iii) a modification of standard methods can result in detection of not only the presence of stenosis, but also the stenosed vessel.
Phosphaturic mesenchymal tumors: radiological aspects and suggested imaging pathway
Authors: Hussein Mohsin A. M. , Cafarelli Francesco Pio , Paparella Maria Teresa , Rennie Winston J. , Guglielmi Giuseppe
Published: August 2021

Phosphaturic mesenchymal tumors (PMTs) are rare mesenchymal neoplasms of soft tissue or bone origin that can give rise to a challenge in diagnostic imaging. These tumors are frequently associated with tumor-induced osteomalacia, also called oncogenic osteomalacia, which is a rare paraneoplastic syndrome characterized by ectopic secretion of fibroblast growth factor 23, a hormone that regulates serum phosphate level. PMTs show polymorphic features on both radiological findings and histological examination, causing problems in diagnosis owing to their similarity with other mesenchymal tumors. Thus, this paper aims to describe radiological aspects of PMTs and suggest an imaging pathway for accurate diagnosis throughout the evidence from the literature review.
Non-material nature’s contributions to people from a marine protected area support multiple dimensions of human well-being
Authors: Garcia Rodrigues João , Villasante Sebastián , Sousa Pinto Isabel
Published: August 2021

The non-material aspects of nature are frequently the most socially valued and demanded nature’s contributions to people (NCP). This is because non-material NCP often lay the foundations of key human well-being dimensions such as identities, experiences, and capabilities. Yet, while research on material NCP such as food and water abound, studies of non-material NCP are relatively scarce. This research gap results in a limited understanding of the relationships between non-material NCP and human well-being, especially in the marine and coastal environment. To understand the relationships between non-material NCP and subjective human well-being, we surveyed 453 users of Litoral Norte—a multiple-use marine protected area in Portugal. Our survey included 16 statement indicators reflecting theoretical constructs of subjective well-being. Using factor analysis, we found that subjective well-being derived from relating to, interacting with, and experiencing marine and coastal sites can be grouped into four interpretable cultural dimensions of well-being. These dimensions are ‘engagement with nature & health’, ‘sense of place’, ‘solitude in nature’, and ‘spirituality’. We also found statistically significant differences in reported levels of the four dimensions of well-being. Reported levels of well-being varied with interviewees’ socio-economic characteristics and environmental behaviour. Our findings offer interesting insights for marine conservation practice and policy that aims to foster both biodiversity and human well-being.
Nitrogen dioxide decline and rebound observed by GOME-2 and TROPOMI during COVID-19 pandemic
Authors: Liu Song , Valks Pieter , Beirle Steffen , Loyola Diego G.
Published: August 2021

Since its first confirmed case in December 2019, coronavirus disease 2019 (COVID-19) has become a worldwide pandemic with more than 90 million confirmed cases by January 2021. Countries around the world have enforced lockdown measures to prevent the spread of the virus, introducing a temporal change of air pollutants such as nitrogen dioxide (NO2) that are strongly related to transportation, industry, and energy. In this study, NO2 variations over regions with strong responses to COVID-19 are analysed using datasets from the Global Ozone Monitoring Experiment-2 (GOME-2) sensor aboard the EUMETSAT Metop satellites and TROPOspheric Monitoring Instrument (TROPOMI) aboard the EU/ESA Sentinel-5 Precursor satellite. The global GOME-2 and TROPOMI NO2 datasets are generated at the German Aerospace Center (DLR) using harmonized retrieval algorithms; potential influences of the long-term trend and seasonal cycle, as well as the short-term meteorological variation, are taken into account statistically. We present the application of the GOME-2 data to analyze the lockdown-related NO2 variations for morning conditions. Consistent NO2 variations are observed for the GOME-2 measurements and the early afternoon TROPOMI data: regions with strong social responses to COVID-19 in Asia, Europe, North America, and South America show strong NO2 reductions of $\sim $
∼
30–50% on average due to restriction of social and economic activities, followed by a gradual rebound with lifted restriction measures.
Measuring aggregate electricity savings from the diffusion of more efficient lighting technologies
Authors: Moral-Carcedo Julián , Pérez-García Julián
Published: August 2021

Increasing concerns about sustainability and energy conservation, coupled with the proliferation of incentives in the EU to achieve energy savings, suggest that significant improvements in energy efficiency should be realized. A policy measure that should have a direct impact on energy savings is the replacement of incandescent and halogen light bulbs by more efficient lighting technologies, which was implemented in 2009. Due to the lack of detailed data, it is not feasible to measure the effect of energy-efficient improvements on electricity consumption at the aggregate level using a bottom-up approach. To overcome this limitation, this paper analyzes hourly electricity demand in a very specific period of the day: the transition from day to night. In this short period, it is plausible that lighting is the main driver of changes in electricity demand, thus making it possible to estimate the increase in electricity consumption when lights are switched on and to analyze the effects of higher energy efficiency in lighting, if any. The results of the analysis for Spain show that during the periods 2009–2011 and 2015–2016, an estimated energy savings of 251 GWh can be attributed to a reduction in the magnitude of the lighting effect, which accounts for 20.3% of the observed decrease in electricity consumption during these two periods.
1H, 13C and 15N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2
Authors: Richter Christian , Hohmann Katharina F. , Toews Sabrina , Mathieu Daniel , Altincekic Nadide , Bains Jasleen Kaur , Binas Oliver , Ceylan Betül , Duchardt-Ferner Elke , Ferner Jan , Fürtig Boris , Grün J. Tassilo , Hengesbach Martin , Hymon Daniel , Jonker Hendrik R. A. , Knezic Bozana , Korn Sophie M. , Landgraf Tom , Löhr Frank , Peter Stephen A. , Pyper Dennis J. , Qureshi Nusrat S. , Schlundt Andreas , Schnieders Robbin , Stirnal Elke , Sudakov Alexey , Vögele Jennifer , Weigand Julia E. , Wirmer-Bartoschek Julia , Witt Kerstin , Wöhnert Jens , Schwalbe Harald , Wacker Anna
Published: August 2021

The stem-loop (SL1) is the 5'-terminal structural element within the single-stranded SARS-CoV-2 RNA genome. It is formed by nucleotides 7–33 and consists of two short helical segments interrupted by an asymmetric internal loop. This architecture is conserved among Betacoronaviruses. SL1 is present in genomic SARS-CoV-2 RNA as well as in all subgenomic mRNA species produced by the virus during replication, thus representing a ubiquitous cis-regulatory RNA with potential functions at all stages of the viral life cycle. We present here the 1H, 13C and 15N chemical shift assignment of the 29 nucleotides-RNA construct 5_SL1, which denotes the native 27mer SL1 stabilized by an additional terminal G-C base-pair.
Fertility Behavior of Turkish Migrant Men in Europe Compared to Stayers at Origin
Authors: Milewski Nadja , Baykara-Krumme Helen
Published: August 2021

This paper addresses the fertility behavior of Turkish men in Europe from a context of origin perspective. Men of the first and subsequent migrant generations are compared with “stayers” from the same regions of origin in Turkey. We pay special attention to the men’s reasons for migration by distinguishing between work and nonwork motivations for migration. We use data from the 2000 Families Study, which was conducted in 2010 and 2011 in Turkey and in western European countries; the sample consists of about 3,500 men. We analyze the transitions to fatherhood as well as to second and third births using event-history analyses; and we investigate the cumulated number of children using Poisson regression analysis. As the men were aged 18–92 at the data collection, we carry out separate models for birth cohort groups. Our findings provide support for the hypothesis of the interrelatedness of events. First-generation migrant men show elevated first birth transitions, which are closely linked to marriage and migration. However, in contrast to the pattern that is often found for women, this effect is observed for labor as well as for nonwork migrants. The rates of transition to a second and a third birth differ less from those of stayers. Analyses of cumulated fertility at age 41 or older further suggest that the migrants’ overall numbers of children are smaller than those of the stayers in Turkey. Thus, our findings indicate that there are dissimilation processes and crossover trends among emigrant men characterized by higher rates of transition to family formation linked to migration but lower overall fertility.
GAMPAL: an anomaly detection mechanism for Internet backbone traffic by flow size prediction with LSTM-RNN
Authors: Wakui Taku , Kondo Takao , Teraoka Fumio
Published: August 2021

This paper proposes a general-purpose anomaly detection mechanism for Internet backbone traffic named GAMPAL (General-purpose Anomaly detection Mechanism using Prefix Aggregate without Labeled data). GAMPAL does not require labeled data to achieve general-purpose anomaly detection. For scalability to the number of entries in the BGP RIB (Border Gateway Protocol Routing Information Base), GAMPAL introduces prefix aggregate. The BGP RIB entries are classified into prefix aggregates, each of which is identified with the first three AS (Autonomous System) numbers in the AS_PATH attribute. GAMPAL establishes a prediction model for traffic sizes based on past traffic sizes. It adopts a LSTM-RNN (Long Short-Term Memory Recurrent Neural Network) model that focuses on the periodicity of the Internet traffic patterns at a weekly scale. The validity of GAMPAL is evaluated using real traffic information, BGP RIBs exported from the WIDE backbone network (AS2500), a nationwide backbone network for research and educational organizations in Japan, and the dataset of an ISP (Internet Service Provider) in Spain. As a result, GAMPAL successfully detects anomalies such as increased traffic due to an event, DDoS (Distributed Denial of Service) attacks targeted at a stub organization, a connection failure, an SSH (Secure Shell) scan attack, and anomaly spam.
A Machine Learning Methodology for Identification and Triage of Heart Failure Exacerbations
Authors: Morrill James , Qirko Klajdi , Kelly Jacob , Ambrosy Andrew , Toro Botros , Smith Ted , Wysham Nicholas , Fudim Marat , Swaminathan Sumanth
Published: August 2021

Inadequate at-home management and self-awareness of heart failure (HF) exacerbations are known to be leading causes of the greater than 1 million estimated HF-related hospitalizations in the USA alone. Most current at-home HF management protocols include paper guidelines or exploratory health applications that lack rigor and validation at the level of the individual patient. We report on a novel triage methodology that uses machine learning predictions for real-time detection and assessment of exacerbations. Medical specialist opinions on statistically and clinically comprehensive, simulated patient cases were used to train and validate prediction algorithms. Model performance was assessed by comparison to physician panel consensus in a representative, out-of-sample validation set of 100 vignettes. Algorithm prediction accuracy and safety indicators surpassed all individual specialists in identifying consensus opinion on existence/severity of exacerbations and appropriate treatment response. The algorithms also scored the highest sensitivity, specificity, and PPV when assessing the need for emergency care.

Lay summary

Here we develop a machine-learning approach for providing real-time decision support to adults diagnosed with congestive heart failure. The algorithm achieves higher exacerbation and triage classification performance than any individual physician when compared to physician consensus opinion.

Graphical abstract
Molecular epidemiology of coxsackievirus A16 circulating in children in Beijing, China from 2010 to 2019
Authors: Hu Ya-Fang , Jia Li-Ping , Yu Fang-Yuan , Liu Li-Ying , Song Qin-Wei , Dong Hui-Jin , Deng Jie , Qian Yuan , Zhao Lin-Qing , Deng Li , Huang Hui , Zhu Ru-Nan
Published: August 2021

Background

Coxsackievirus A16 (CVA16) is one of the major etiological agents of hand, foot and mouth disease (HFMD). This study aimed to investigate the molecular epidemiology and evolutionary characteristics of CVA16.

Methods

Throat swabs were collected from children with HFMD and suspected HFMD during 2010–2019. Enteroviruses (EVs) were detected and typed by real-time reverse transcription-polymerase chain reaction (RT-PCR) and RT-PCR. The genotype, evolutionary rate, the most recent common ancestor, population dynamics and selection pressure of CVA16 were analyzed based on viral protein gene (VP1) by bioinformatics software.

Results

A total of 4709 throat swabs were screened. EVs were detected in 3180 samples and 814 were CVA16 positive. More than 81% of CVA16-positive children were under 5 years old. The prevalence of CVA16 showed obvious periodic fluctuations with a high level during 2010–2012 followed by an apparent decline during 2013–2017. However, the activities of CVA16 increased gradually during 2018–2019. All the Beijing CVA16 strains belonged to sub-genotype B1, and B1b was the dominant strain. One B1c strain was detected in Beijing for the first time in 2016. The estimated mean evolutionary rate of VP1 gene was 4.49 × 10–3 substitution/site/year. Methionine gradually fixed at site-23 of VP1 since 2012. Two sites were detected under episodic positive selection, one of which (site-223) located in neutralizing linear epitope PEP71.

Conclusions

The dominant strains of CVA16 belonged to clade B1b and evolved in a fast evolutionary rate during 2010–2019 in Beijing. To provide more favorable data for HFMD prevention and control, it is necessary to keep attention on molecular epidemiological and evolutionary characteristics of CVA16.
Composting as Sustainable Managing Option for Seaweed Blooms on Recreational Beaches
Authors: Madejón Engracia , Panettieri Marco , Madejón Paula , Pérez-de-Mora Alfredo
Published: August 2021

Purpose

Seaweed blooms are an irregular but frequent phenomenon in many coastal areas and during the touristic season, can cause limitations for recreational use of beaches. Here, we propose composting of seaweed removed from the shoreline as alternative to current management practices (e.g. disposal in landfills or incineration).

Methods

A co-composting strategy with garden prune waste was chosen for the treatment of seaweed blooms removed from the beaches. Composting was performed in windrows of 10 m long, 1.5 m wide and 1 m high using different ratios of algae and garden prune residues (1:2; 1:1 and 2:1) at a composting facility in Rota (Cádiz, Spain).

Results

Characteristic temperature profiles consisting of a very brief mesophilic phase, a 15–20-day thermophilic phase (maximum of 50–70 °C) and a second mesophilic phase (40–35ºC) after 30–50 days were observed. After curing for more than 160 days, a stabilized non-phytotoxic composted material (50–70 g kg−1 C; 2–3 g kg−1 N; C/N ratio of 21–27 and electrical conductivity between 1.8–2.4 mS cm−1) was obtained. Composting worked best using a 2:1 ratio (prune waste:algae). The composted organic material showed larger presence of stabilized lignin-derived compounds as assessed via nuclear magnetic resonance. No odors were detected during the composting process suggesting that open-air treatment is feasible.

Conclusion

The co-composting strategy provides a safe, local and sustainable approach to deal with seaweed blooms during peaks of recreational use and in situations where algae have to be removed.

Graphic Abstract
Karst groundwater vulnerability assessment: application of an integrative index-based approach to main catchments of middle Valseriana springs (Northern Italy)
Authors: Citrini Andrea , Camera Corrado A. S. , Alborghetti Francesca , Beretta Giovanni Pietro
Published: August 2021

The study aim was to assess the intrinsic vulnerability of the middle Valseriana (northern Italy) through a methodology that could fully consider the peculiar characteristics of the Pre-Alps region. After applying classical methods for karst environments (COP and EPIK), the integrative COPA+K method was developed for the Nossana (dominant drainage system) and Ponte del Costone (dispersive circulation system) spring catchments. The COPA+K approach exploits the potential of the COP method with the addition of two factors: the influence of the main discontinuities on the water system according to their distance from the spring (A factor), and the development of the karst network (K factor). The COP and COPA+K maps were validated based on the characteristic correlation, for the study area, between the values of δ18O and the elevation of recharge areas. Compared to COP, the COPA+K results appeared more stringent in the identification of areas characterized by high vulnerability, which passed from 35.6% to 23.6% of the entire study area. COPA+K also made possible to better differentiate the behavior of the two catchments. In terms of high susceptible areas, their percentage difference increased by 12.3%, correctly emphasizing the greater susceptibility of the Nossana drainage system in comparison with the Ponte del Costone dispersive one. For the COPA+K map, in the Nossana catchment, the δ18O values indicated a good agreement between the mean elevation of high vulnerable and water recharge areas (± 106 m). For Ponte del Costone, the isotopic data indicated a possible mixing with the waters of the Serio River.
Platelet Activation and Chemokine Release Are Related to Local Neutrophil-Dominant Inflammation During Hyperacute Human Stroke
Authors: Kollikowski Alexander M. , Pham Mirko , März Alexander G. , Papp Lena , Nieswandt Bernhard , Stoll Guido , Schuhmann Michael K.
Published: August 2021

Experimental evidence has emerged that local platelet activation contributes to inflammation and infarct formation in acute ischemic stroke (AIS) which awaits confirmation in human studies. We conducted a prospective observational study on 258 consecutive patients undergoing mechanical thrombectomy (MT) due to large-vessel-occlusion stroke of the anterior circulation (08/2018–05/2020). Intraprocedural microcatheter aspiration of 1 ml of local (occlusion condition) and systemic arterial blood samples (self-control) was performed according to a prespecified protocol. The samples were analyzed for differential leukocyte counts, platelet counts, and plasma levels of the platelet-derived neutrophil-activating chemokine C-X-C-motif ligand (CXCL) 4 (PF-4), the neutrophil attractant CXCL7 (NAP-2), and myeloperoxidase (MPO). The clinical-biological relevance of these variables was corroborated by specific associations with molecular-cellular, structural-radiological, hemodynamic, and clinical-functional parameters. Seventy consecutive patients fulfilling all predefined criteria entered analysis. Mean local CXCL4 (+ 39%: 571 vs 410 ng/ml, P = .0095) and CXCL7 (+ 9%: 693 vs 636 ng/ml, P = .013) concentrations were higher compared with self-controls. Local platelet counts were lower (− 10%: 347,582 vs 383,284/µl, P = .0052), whereas neutrophil counts were elevated (+ 10%: 6022 vs 5485/µl, P = 0.0027). Correlation analyses revealed associations between local platelet and neutrophil counts (r = 0.27, P = .034), and between CXCL7 and MPO (r = 0.24, P = .048). Local CXCL4 was associated with the angiographic degree of reperfusion following recanalization (r =  − 0.2523, P = .0479). Functional outcome at discharge correlated with local MPO concentrations (r = 0.3832, P = .0014) and platelet counts (r = 0.288, P = .0181). This study provides human evidence of cerebral platelet activation and platelet-neutrophil interactions during AIS and points to the relevance of per-ischemic thrombo-inflammatory mechanisms to impaired reperfusion and worse functional outcome following recanalization.
Isotropic uncharged model with compactness and stable configurations
Authors: Prasad Amit Kumar , Kumar Jitendra , Kumar Ashok
Published: August 2021

In this study we have obtained a new exact model for relativistic stellar object by solving Einstein’s field equation with help of Buchdahl metric. The model is capable to represent some known compact stars like Her X-1,4U 1538-52 and SAX J1808.4-3658. The model satisfies the regularity, casuality, stability and energy conditions. Using the Tolman–Oppenheimer–Volkoff equations, we explore the hydrostatic equilibrium for an uncharged case. We have also compared these conditions with graphical representations that provide strong evidences for more realistic and viable models.
Hybrid type multi-robot path planning of a serial manipulator and SwarmItFIX robots in sheet metal milling process
Authors: Veeramani Satheeshkumar , Muthuswamy Sreekumar
Published: August 2021

This work investigates on the coordinated locomotion between a ceiling-mounted serial manipulator and two SwarmItFIX robots. The former holds the machining tool as an end effector, and the other two robots act as swarm robotic fixtures in a sheet metal milling process. A novel offline coordination planner which follows the hierarchical based hybrid type decentralized planning strategy has been proposed. Motion of the serial manipulator and SwarmItFIX robots’ coordinated locomotion are divided into three sub-problems, viz, trajectory planning of serial manipulator, task planning of SwarmItFIX robots, and homogenous prioritized multi-robot path planning of SwarmItFIX robots. Mathematical formulation of all the three sub-problems is developed and presented in this paper. A hexagonal segment that fits inside the boundaries of the workspace is considered as the machining trajectory. The tool velocity is assumed to be constant as it improves the quality of machining. The results obtained from the proposed planner is found to be efficient as the task planning module has computed the precise support locations and support duration for the SwarmItFIX robots. The multi-robot path planning module of the planner computes the optimal collision-free paths of SwarmItFIX robots for all goal positions. Finally, trajectories of SwarmItFIX robots are found to be completely in-line with the trajectory of tool center point (TCP) of the serial manipulator.
Hybrid artificial neural network and structural equation modelling techniques: a survey
Authors: Albahri A. S. , Alnoor Alhamzah , Zaidan A. A. , Albahri O. S. , Hameed Hamsa , Zaidan B. B. , Peh S. S. , Zain A. B. , Siraj S. B. , Masnan A. H. B. , Yass A. A.
Published: August 2021

Topical treatments with structural equation modelling (SEM) and an artificial neural network (ANN), including a wide range of concepts, benefits, challenges and anxieties, have emerged in various fields and are becoming increasingly important. Although SEM can determine relationships amongst unobserved constructs (i.e. independent, mediator, moderator, control and dependent variables), it is insufficient for providing non-compensatory relationships amongst constructs. In contrast with previous studies, a newly proposed methodology that involves a dual-stage analysis of SEM and ANN was performed to provide linear and non-compensatory relationships amongst constructs. Consequently, numerous distinct types of studies in diverse sectors have conducted hybrid SEM–ANN analysis. Accordingly, the current work supplements the academic literature with a systematic review that includes all major SEM–ANN techniques used in 11 industries published in the past 6 years. This study presents a state-of-the-art SEM–ANN classification taxonomy based on industries and compares the effort in various domains to that classification. To achieve this objective, we examined the Web of Science, ScienceDirect, Scopus and IEEE Xplore® databases to retrieve 239 articles from 2016 to 2021. The obtained articles were filtered on the basis of inclusion criteria, and 60 studies were selected and classified under 11 categories. This multi-field systematic study uncovered new research possibilities, motivations, challenges, limitations and recommendations that must be addressed for the synergistic integration of multidisciplinary studies. It contributed two points of potential future work resulting from the developed taxonomy. First, the importance of the determinants of play, musical and art therapy adoption amongst autistic children within the healthcare sector is the most important consideration for future investigations. In this context, the second potential future work can use SEM–ANN to determine the barriers to adopting sensing-enhanced therapy amongst autistic children to satisfy the recommendations provided by the healthcare sector. The analysis indicates that the manufacturing and technology sectors have conducted the most number of investigations, whereas the construction and small- and medium-sized enterprise sectors have conducted the least. This study will provide a helpful reference to academics and practitioners by providing guidance and insightful knowledge for future studies.
Movement building responses to COVID-19: lessons from the JASS mobilisation fund
Authors: Okech Awino , Essof Shereen , Carlsen Laura
Published: August 2021

This article draws on the work of Just Associates (JASS), a feminist movement support organisation that strengthens the leadership and organising capacity of community-based women networks in Southern Africa, Southeast Asia, and Mesoamerica, to transform the structures that perpetuate inequality and violence. We analyse qualitative interviews and surveys drawn from recipients of the JASS mobilisation fund (JMF), an innovative financial crisis support mechanism for feminist movements. We argue that localisation strategies deployed by women’s networks supported by the JMF in response to COVID-19, challenge dominant humanitarian responses that de-centre feminist movements, local knowledge, and expertise. By accounting for local knowledge generated from long histories of movement building, building collective power, and challenging racialised and gendered responses to humanitarian crises, women’s collectives and networks supported through the JMF developed contextually relevant responses that challenge patriarchal structural barriers heightened by COVID-19.
Golovinomyces longipes (Noordel. & Loer.) L. Kiss on Matricaria chamomilla L.: another host range expansion
Authors: Götz M. , Braun U.
Published: August 2021

Golovinomyces longipes is a widespread powdery mildew on Solanaceae (Nicotiana, Petunia and Solanum spp.). In the past, it has been reported only once on Verbena (Verbenaceae), a non-solanaceaous host. Recently, this powdery mildew has been found on the composite Matricaria chamomilla. The identification of the powdery mildew species on this unusual host has been proved by morphological studies and DNA sequence analysis. Both datasets coincide with the characteristic data for G. longipes on Solanaceae. First inoculation experiments with further composites resulted in an infection of Brachyscome hybrid ‘Surdaisy’. To our knowledge, this is the first report of G. lonigpes on hosts belonging to the important family of Asteraceae and an additional proof of the broader host range of G. longipes beyond the Solanaceae.
Seismic ground response by twin lined tunnels with different cross sections
Authors: Panji Mehdi , Mojtabazadeh-Hasanlouei Saeed
Published: August 2021

In this paper, the geometrical effects of shallow twin lined tunnels with different cross sections are investigated to obtain the anti-plane seismic ground motion under vertical/horizontal incident planeSHwaves. A model of long two-dimensional lined tunnels is established and embedded in a homogeneous linear elastic half-plane by an applied numerical time-domain boundary element approach. In addition to a brief introduction to the formulation of the method, by considering five tunnel sections including circular, elliptical, horseshoe, square and rectangular, the surface response is sensitized to observe the normalized displacement amplitude/amplification ratio. In this regard, the angle of the incident wave and the frequency of the response are also included in changing the response pattern. To illustrate the results in both time and frequency domains, they are presented as blanket charts, snapshots, and three-/two-dimensional diagrams. The results showed that the seismic response of the surface is extremely affected by the geometric parameters of underground tunnels, which can create different conditions on the ground surface with shifting the direction of the wavefront.

Article Highlights

Geometrical effect of twin horizontally overlapping lined tunnels.

Applying a time-domain half-plane boundary element method.

Illustrating the response in time and frequency domains.

The effect of depth and distance ratios on the seismic ground motion.

Propagating vertical and horizontal incident SH-wave type.

Graphic Abstract
Economic Diversification Trends in the Gulf: the Case of Saudi Arabia
Authors: Al Naimi Sarah Muhanna
Published: August 2021

A national economy which is dependent on income from just one source is vulnerable, especially when that income comes from non-renewable resources. The sustainable prosperity of an economy thus relies on the successful implementation of economic diversification. Diversification is key to creating an attractive, flourishing environment in a country and improving the quality of its institutions and its citizens’ lives. The countries of the Gulf Cooperation Council (GCC) are accelerating their efforts to achieve economic diversification, with their national visions reflecting a shared aim of securing permanent high standards of living for future generations. After the first boom in oil prices in 1970, Saudi Arabia’s government introduced primary development plans to diversify its economy. In 2016, it announced its 2030 vision to establish sustainable growth through economic diversification. The economic diversification strategy of Saudi Arabia is founded on several pillars, including investment in human capital and education and investment in non-oil sectors such as tourism. This paper aims to analyze the economic diversification trends in the GCC region with a special focus on Saudi Arabia as a case study. Within this wider context, the paper will concentrate on Saudi Arabia’s efforts to achieve diversification by building a knowledge-based economy. Focusing on the quality of education and research improves the human capital available in the country which contributes to the growth of the economy. Results reveal that although Saudi Arabia has embarked on its diversification plans, the current status of oil prices, the deficit in the Saudi general budget, and the country’s traditional educational system will hinder and slow this process.
Editorial
Authors: Barrett Steve
Published: August 2021

Heavy-duty mobility continues to be a key focus for the fuel cell sector, as we see further deployments and demonstration projects focusing on fuel cell electric trucks.
Present‐Day Activity of the Anninghe Fault and Zemuhe Fault, Southeastern Tibetan Plateau, Derived From Soil Gas CO2Emissions and Locking Degree
Authors: Yang Yao , Li Ying , Li Youguo , Ji Lingyun , Gong Yue , Du Fang , Zhang Lei , Chen Zhi
Published: August 2021

The Anninghe fault (ANHF) and the Zemuhe fault (ZMHF), located in the southeast of the Tibetan Plateau, have a high level of seismic hazard and are among the most active faults in China. This study performed the first measurements of soil gas CO2at three sites across the ANHF and the ZMHF. The fault locking (FL) depth and extent of different segments of the ANHF and the ZMHF were inverted using the negative dislocation model based on global positioning system velocity data acquired during 2009–2015. Results showed that the degassing intensity of CO2in the ZMHF is substantially higher than in the ANHF, which is spatially consistent with the degree of inverted FL. The inversion results revealed that the level of coupling, including the locking depth and extent, along the southern segment of the ANHF is markedly greater than in the northern segment of the ZMHF. Soil gas CO2geochemistry yielded different spatially anomalous features, indicating that the faults have different properties and permeability. The intensive locking of the ANHF and ZMHF segments has reduced permeability through self‐sealing processes, which has restricted the escape of gas from the deep crust. Correspondingly, a creeping fault with a low level of coupling could maintain high permeability, which would be favorable for CO2migration.
Radio Frequency Characteristics of Volcanic Lightning and Vent Discharges
Authors: Behnke Sonja A. , Edens Harald , Senay Seda , Iguchi Masato , Miki Daisuke
Published: August 2021

In this study, we analyze the pulse width and spectral content of vent discharges and volcanic lightning flashes. We made measurements of electrical activity with a broadband very high frequency antenna (20–80 MHz) during an explosive eruption of Sakurajima volcano on November 8, 2019. The individual impulses that comprise vent discharges and volcanic lightning were analyzed to determine the fundamental width of the impulses and the rate of fall‐off of their energy spectral density. The results show that vent discharges are more similar to volcanic lightning than they are different. The mean pulse width for both vent discharges and volcanic lightning was 50 ns. Both types of electrical activity had similar spectral content; the average slope of the amplitude spectra was −3.4 for both. Further, examination of the pulse width and spectral slope distributions showed that while the distributions of volcanic lightning and vent discharges are statistically distinct from each other, the distribution of vent discharges is a subset of the distribution of volcanic lightning.
Reconciling the Infrared and Microwave Observations of the Lunar South Pole: A Study on Subsurface Temperature and Regolith Density
Authors: Feng Jianqing , Siegler Matthew A.
Published: August 2021

The Diviner Lunar Radiometer Experiment on the Lunar Reconnaissance Orbiter and the Microwave Radiometer (MRM) onboard Chang'e‐2 (CE‐2) orbiter performed nearly coincident measurements of the lunar south polar region in 2010–2011. In this study, we reconcile infrared data from Diviner and microwave data from MRM to reveal thermal behavior of lunar regolith at very low temperatures. Assuming a uniform density structure and dielectric properties across the polar region, we retrieve a relative apparent thermal‐gradient map based on radiative transfer model. The result shows apparent thermal gradients in the permanently shadowed regions (PSRs) are much larger than that in non‐PSRs, which implies a systematic difference in thermal conductivity and/or density of lunar regolith in PSRs. We also model surface temperature and microwave brightness temperature over time in PSR and non‐PSR locations. The modeling results at these representative locations and the thermal gradient map confirm that the regolith in the PSRs is consistent with a much lower thermal conductivity and higher porosity than non‐PSRs.
Impacts of Drying and Rewetting on the Radiocarbon Signature of Respired CO2 and Implications for Incubating Archived Soils
Authors: Beem‐Miller Jeffrey , Schrumpf Marion , Hoyt Alison M. , Guggenberger Georg , Trumbore Susan
Published: August 2021

The radiocarbon signature of respired CO2 (∆14C‐CO2) measured in laboratory soil incubations integrates contributions from soil carbon pools with a wide range of ages, making it a powerful model constraint. Incubating archived soils enriched by “bomb‐C” from mid‐20th century nuclear weapons testing would be even more powerful as it would enable us to trace this pulse over time. However, air‐drying and subsequent rewetting of archived soils, as well as storage duration, may alter the relative contribution to respiration from soil carbon pools with different cycling rates. We designed three experiments to assess air‐drying and rewetting effects on ∆14C‐CO2 with constant storage duration (Experiment 1), without storage (Experiment 2), and with variable storage duration (Experiment 3). We found that air‐drying and rewetting led to small but significant (α < 0.05) shifts in ∆14C‐CO2 relative to undried controls in all experiments, with grassland soils responding more strongly than forest soils. Storage duration (4–14 y) did not have a substantial effect. Mean differences (95% CIs) for experiments 1, 2, and 3 were: 23.3‰ (±6.6), 19.6‰ (±10.3), and 29.3‰ (±29.1) for grassland soils, versus −11.6‰ (±4.1), 12.7‰ (±8.5), and −24.2‰ (±13.2) for forest soils. Our results indicate that air‐drying and rewetting soils mobilizes a slightly older pool of carbon that would otherwise be inaccessible to microbes, an effect that persists throughout the incubation. However, as the bias in ∆14C‐CO2 from air‐drying and rewetting is small, measuring ∆14C‐CO2 in incubations of archived soils appears to be a promising technique for constraining soil carbon models.