bluuebunny/crossref_metadata_2025 huggingface dataset:
The coronavirus: Black swan and endowment shock
Authors: Peña Blasco Guillermo
Published: May 2021

An external shock caused by an extraordinary and unpredictable effect, a “black swan” like COVID-19, is analyzed. It implies a shift of endowment in financial markets, and its effects on economic inequality, financial deepening and total economic income. Theoretical models are proposed, where the public sector seeks alternatives to a lockdown, allowing self-regulation of the economy, taxing capital or seeking joint policies with other states. In the first model, the economy is self-regulating with the help of the financial sector. Nonetheless, inequality is generated and in other models, the public sector tries to intervene. First, the public sector minimizes inequality by taxing capital, allowing a redistribution of wealth and income, with a tax rate that depends only on the differential impacts of the black swan on the different markets. Finally, a coordination of policies between the different countries affected is proposed to prevent black swans and other negative externalities. This is feasible depending on the tax rate, household benefits and administration costs
La economía de la Unión Europea en tiempos de COVID-19
Authors: Rueda Cantuche Jose Manuel
Published: May 2021

La pandemia de la COVID-19 está teniendo un impacto sin precedentes en la economía europea. En este artículo vamos a analizar las últimas cifras publicadas por Eurostat para 2020 y el último informe de proyección económica publicado por la Comisión Europea, proporcionando además una descripción más detallada del impacto de la pandemia por sectores. Usamos para ello el modelo Trade-SCAN desarrollado por el Centro Común de Investigación de la Comisión Europea. Según nuestro análisis, España lidera los resultados más negativos en términos de empleo y PIB, principalmente en los cuatro sectores másafectados en la UE, a saber: el comercio; las actividades artísticas, deportivas, culturales y recreativas; los servicios a empresas; y las actividades de alojamiento, comidas y bebidas. Es remarcable el hecho diferencial de Irlanda, único país con crecimiento de su PIB, fundamentalmente debido a sus exportaciones de productos farmacéuticos y servicios de tecnología de la información. En global, la economía europea ha caído finalmente en 2020 un 6,1%, con ciertos patrones comunes en términos sectoriales en cada uno de sus países, a excepción de algunos casos como la agricultura rumana o la construcción en Irlanda, entre otros.
Carboxymethylated pulp as starting point to prepare hydroxypropylmethyl cellulose with enhanced gel rheological properties in an aqueous medium
Authors: Hamed Othman , Al-Kerm Rana , Al-Kerm Rola , Qrareya Hisham , Deghles Abdalhadi , Dagdag Omar
Published: May 2021

Hydroxypropyl methylcellulose in an aqueous solution upon heating tends to undergo thermal gelation, where the polymer chains form a network and precipitate from solution. This occurs at a temperature known as thermal gelation point. Polymer precipitation causes a significant drop in the shear viscosity. This could be a disadvantage in a hot environment or in applications were heat is applied. In this work, a hydroxypropylmethyl cellulose (HPMC) was formed that undergoes thermal gelation with no polymer precipitation and with enhanced rheological properties. The target HPMC was prepared from wood pulp with a low content of carboxymethyl groups. The produced hydroxypropyl methylcellulose (CMHPMC) derivative showed unique physical properties that are not achievable with typical hydroxypropyl methylcellulose. The thermal gelation temperature of an aqueous solution of CMHPMC was increased from 55 °C for commercial HPMC to 85 °C for CMHPMC. A substitution level of carboxymethylation that led to an HPMC with a thermal gelation and with no precipitation was determined to be a 0.15 of carboxyl groups per anhydroglucose repeat unit. In addition, the carboxymethylated pulp showed an enhanced reactivity towards etherification reactions.
An investigation of wood pallets landfilled and recovered at US municipal solid waste facilities
Authors: Shiner Zachary , Horvath Laszlo , Araman Philip , Gething Brad
Published: May 2021

The purpose of this research was to investigate the total number of pallets that end up in landfills in the United States as well as to gain a better understanding of the overall waste stream. This research was conducted by mailing all of the licensed Municipal Solid Waste (MSW) facilities in the continental United States a questionnaire that included the option to complete the survey online. The questionnaire that was sent to the landfills was built upon previous surveys conducted by researchers at Virginia Tech in both 1995 and 1998. The results indicated that an estimated 249 million tons of MSW was received at landfills nationwide. This was an increase from the 239 million tons of MSW in 1998. Only 13.1 million pallets were landfilled in 2016, which was over a 90% decrease from the 138 million pallets landfilled in 1998. At the same time, approximately 15.9 million pallets were recovered, repurposed, or reused at the surveyed MSW facilities, which was a decrease from the 22 million pallets recovered in 1998. The results of this research indicate that fewer pallets are making their way to landfills, and a greater proportion of pallets reaching MSW facilities are being recovered.
Longitudinal Associations Between Screen Use and Reading in Preschool-Aged Children
Authors: McArthur Brae Anne , Browne Dillon , McDonald Sheila , Tough Suzanne , Madigan Sheri
Published: May 2021

BACKGROUND AND OBJECTIVES:

The home literacy environment has been identified as a key predictor of children’s language, school readiness, academic achievement, and behavioral outcomes. With the increased accessibility and consumption of digital media, it is important to understand whether screen use impacts off-line enrichment activities such as reading or whether reading activities offset screen use. Using a prospective birth cohort, we examined reading and screen use at 24, 36, and 60 months to elucidate the directional association between screen use and reading over time.

METHODS:

This study included data from 2440 mothers and children in Calgary, Alberta, drawn from the All Our Families cohort. Children’s screen use and reading activities were assessed via maternal report at age 24, 36, and 60 months. Sociodemographic covariates were also collected.

RESULTS:

Using a random-intercepts cross-lagged panel model, which statistically controls for individual-level confounds, this study revealed that greater screen use at 24 months was associated with lower reading at 36 months (β = −.08; 95% confidence interval: −0.13 to −0.02). In turn, lower reading at 36 months was associated with greater screen use at 60 months (β = −.11; 95% confidence interval: −0.19 to −0.02). Covariates did not modify the associations.

CONCLUSIONS:

A reciprocal relationship between screen use and reading was identified. Early screen use was associated with lower reading activities, resulting in greater screen use at later ages. Findings emphasize the need for practitioners and educators to discuss screen use guidelines and encourage families to engage in device-free activities to foster early literacy exposure.
Use of Probiotics in Preterm Infants
Authors: Poindexter Brenda ,   COMMITTEE ON FETUS AND NEWBORN, Cummings James , Hand Ivan , Adams-Chapman Ira , Aucott Susan W. , Puopolo Karen M. , Goldsmith Jay P. , Kaufman David , Martin Camilia , Mowitz Meredith
Published: May 2021

Probiotic products in the United States are available for use in the general category of dietary supplements, bypassing the rigor of the US Food and Drug Administration (FDA) approval process in safety, efficacy, and manufacturing standards. As a result, currently available probiotics lack FDA-approved drug labeling and cannot be marketed to treat or prevent disease in preterm infants, including necrotizing enterocolitis and late-onset sepsis. Despite lack of availability of a pharmaceutical-grade product, the number of preterm infants receiving probiotics in the United States and Canada is steadily increasing. According to recent reports from large collaborative databases in the United States, approximately 10% of extremely low gestational age neonates receive a probiotic preparation during their stay in the NICU, with wide variation in practice among units. In sum, more than 10 000 preterm infants have been enrolled in randomized clinical trials of probiotic supplementation worldwide. Methodologic differences among study protocols included different strains and combinations of therapy, masking of trials, and a priori definitions of the primary outcome measure. Large meta-analyses of these trials have demonstrated the efficacy of multiple-strain probiotics in reducing necrotizing enterocolitis and all-cause mortality, whereas the efficacy of single-strain probiotic preparations is less certain. In the absence of an appropriate medical-grade product in the United States, dietary supplement–grade probiotics, some of which have been the subject of recent recalls for contamination, are being prescribed. Given the lack of FDA-regulated pharmaceutical-grade products in the United States, conflicting data on safety and efficacy, and potential for harm in a highly vulnerable population, current evidence does not support the routine, universal administration of probiotics to preterm infants, particularly those with a birth weight of <1000 g.
The Accuracy of Documented Nursing Care Plan among Registered Nurses
Authors: Alhawsawi Muneerah Mahmood
Published: May 2021

Background: Nursing documentation is a record of care planned and provided by qualified nurses under the guidance of a competent nurse for each patient as well as the clients.

Objective: to provide published studies about accuracy of nursing documentation.

Methods: Searches were conducted using the following electronic databases: PUBMED, MEDLIN, CINAHAL, SAUDI DIGETAL LIBRALY and GOOGLE SCOLAR as gray data base. Search was limited to English-Language publication. And include study over 10year period.

Result: nursing documentations is inaccurate, lacking precision, and low in quality.  Factors that influence nursing documentation differ but are also interrelated with each other. Shortage of employees, insufficient knowledge about the significance of documentation, patient load, lack of hospital education, and lack of support from nurse leaders are the reported challenges to documentation.

Conclusion: Most of the lecture revel the necessary need of nursing documentation practice. Affected factor and with several recommendations for improvement noted.

Keywords:  ''nursing care plan," "nursing documentation,'' "accuracy of documentation" and ''nursing report.''
The role of vitamin D3 deficiency correction in optimizing the treatment of anemia in women with autoimmune diseases
Authors:   SI «Institute of Pediatrics, Obstetrics and Gynecology named after Academician O.M. Lukyanova NAMS of Ukraine», Kyiv, Davydova Iu.V. , Lymanskaya A.Y. ,   SI «Institute of Pediatrics, Obstetrics and Gynecology named after Academician O.M. Lukyanova NAMS of Ukraine», Kyiv, Kravets O.M. ,   SI «Institute of Pediatrics, Obstetrics and Gynecology named after Academician O.M. Lukyanova NAMS of Ukraine», Kyiv
Published: May 2021

The aim is to analyze the effectiveness of correction vitamin D deficiency in the treatment of anemia in women with systemic lupus erythematosus (SLE). Materials and methods. Concomitant documented levels of 25-hydroxyvitamin D, hemoglobin, ferritin, and serum iron in a group of women with SLE who applied for preconception counseling were analyzed. All women were in remission for SLE activity within 5 to 6 months. A total of 54 women were involved in iron metabolism disorders (decreased ferritin, hemoglobin, serum iron). Vitamin D deficiency was detected at <30 ng/ml, and anemia at hemoglobin <120 g/l. Group 1 consisted of 32 women with vitamin D levels <30 ng/ml who received antianemic therapy with ferrous sulfate with ascorbic acid, correction of vitamin D deficiency with Olidetrim 2000 U (Polpharma), and group 2 — women with vitamin D levels <30 ng/ml (n=22) who received antianemic therapy with ferrous sulfate with ascorbic acid and a vitamin complex containing vitamin D 400 U. The groups were comparable by the main demographic indicators (age, education, socio-economic level). In both groups, iron metabolism and 25-hydroxyvitamin D levels were monitored in 4 weeks after treatment. Results and conclusions. Women with SLE have a high risk of chronic inflammatory anemia development, which can be combined with iron deficiency anemia. To improve the results of treatment, it is proposed to introduce supplementation with a high dose of vitamin D (Olidetrim 2000 U), into complex therapy which contributes to the effectiveness of correction of deficiency of this vitamin, as well as the onset of long-term recovery of iron store, hemoglobin concentration. The study was conducted in accordance with the principles of the Declaration of Helsinki. The research protocol was approved by the Local Ethics Committee of the institution mentioned in the work. Informed consent of women was obtained for the research. The authors declare no conflict of interest. Key words: vitamin D deficiency, pregnant women, systemic lupus erythematosus, supplementation.
Types and devices for smoking and their harmful effects on the human body
Authors:   Ivano-Frankivsk National Medical University, Ukraine, Lisetska I.S.
Published: May 2021

The literature review focuses on the prevalence of smoking among the population, the types of smoking devices and their negative impact on public health. The article presents the composition of traditional cigarettes and alternative types of smoking, analyzes the data of smoking statistics in the world. The smoking habit has been known since 2000 BC, when American Indians inhaled the smoke from burning the leaves of the plant Nicotiana tabacum, in the 20th century became an epidemic and killed more than 100 million people, and according to forecasts in the XXI century, this figure may grow in order. It is alarming that in recent decades, in addition to traditional cigarettes, alternative types of smoking have become popular, especially among adolescents and young people, namely electronic cigarettes (E-cigarettes, vapes), tobacco heating devices (IQOS), and sometimes products. With low tobacco content (snuff, chewing tobacco, etc.). In addition, hookah remains fashionable and sometimes prestigious among young people, which also has a detrimental effect on the human body. Smoking both traditional cigarettes and alternative types is one of the important medical and social problems both in Ukraine and around the world, as it is widespread and available. Smoking is a risk factor for human health and, as a result, an increase in nicotine-related mortality. At the same time, smoking is the only cause of illness and death that can be eliminated. Today, smoking is considered not as a bad habit, but as a chronic disease, prone to recurrence, even long after smoking cessation. There are no safe types of smoking, active and passive smoking are equally harmful to the body, which undermines human health and threatens his life. Smoking is especially dangerous for adolescents and young adults. The fight against smoking remains a key factor in the recovery of the nation. Smoking cessation is not only a matter of prevention, it should be considered as one of the appointments for the patient in the treatment of any disease and rehabilitation, because without it there will be no success in treatment and health. No conflict of interest was declared by the author. Key words: smoking, cigarettes, nicotine, electronic cigarettes, IQOS, hookah, snus.
Bioinformatic approaches for analysis of coral-associated bacteria using R programming language
Authors: Thi Nhung Doan , Van Ngoc Bui
Published: May 2021

Recent advances in metagenomics and bioinformatics allow the robust analysis of the composition and abundance of microbial communities, functional genes, and their metabolic pathways. So far, there has been a variety of computational/statistical tools or software for analyzing microbiome, the common problems that occurred in its implementation are, however, the lack of synchronization and compatibility of output/input data formats between such software. To overcome these challenges, in this study context, we aim to apply the DADA2 pipeline (written in R programming language) instead of using a set of different bioinformatics tools to create our own workflow for microbial community analysis in a continuous and synchronous manner. For the first effort, we tried to investigate the composition and abundance of coral-associated bacteria using their 16S rRNA gene amplicon sequences. The workflow or framework includes the following steps: data processing, sequence clustering, taxonomic assignment, and data visualization. Moreover, we also like to catch readers’ attention to the information about bacterial communities living in the ocean as most marine microorganisms are unculturable, especially residing in coral reefs, namely, bacteria are associated with the coral Acropora tenuis in this case. The outcomes obtained in this study suggest that the DADA2 pipeline written in R programming language is one of the potential bioinformatics approaches in the context of microbiome analysis other than using various software. Besides, our modifications for the workflow execution help researchers to illustrate metagenomic data more easily and systematically, elucidate the composition, abundance, diversity, and relationship between microorganism communities as well as to develop other bioinformatic tools more effectively.
Whole exome sequencing identified a pathogenic mutation of COL2A1 causing Stickler syndrome in a Vietnamese family
Authors: Ton Nguyen Dang , Minh Chau Pham , Thu Trang Duong , Thi Xuan Nguyen , Xuan Hiep Nguyen , Hai Ha Nguyen
Published: May 2021

Stickler syndrome is a group of rare inherited diseases associated with abnormalities in connective tissues, specifically collagen of the eyes, ears, craniofacies, skeleton and joints. The inheritance pattern of this disease is either an autosomal dominant or an autosomal recessive based on the causative gene. Stickler syndrome is characterized by severe nearsightedness, vitreous abnormalities, distinctive facial features, hearing problems and joint anomalies. Herein, we report a case of a 37-year-old man from Vietnam suspected of Stickler syndrome, presenting a phenotype of retinal detachment and complete loss of vision, and his 3-year-old son with congenital high myopia and vitreous abnormalities. Genetic analysis using whole exome sequencing (WES) revealed a nucleotide substitution (c.C2818T/p.R940X) in exon 42 of the COL2A1 gene that was previously reported as a pathogenic variant causing Stickler syndrome. Validation of COL2A1 c.C2818T in all members of this family by using Sanger sequencing detected the presence of this pathogenic variant in the heterozygous form in the affected father and son but not in the mother and another son without any signs of a vision problem. Thus, our study contributes to not only the knowledge base of clinical and genetic aspects of Stickler syndrome in Vietnam but also the awareness of the importance of genetic counseling in patients with COL2A1 c.C2818T mutation, as well as early diagnosis and appropriate treatment to prevent serious complications, especially blindness.
Association of AhRR rs2292596 with male infertility in 422 Vietnamese individuals
Authors: Huu Dinh Tran , Xuan Canh Nguyen , Huong Thao Dinh , Lan Anh Luong Thi , Minh Duc Bui , Thuy Duong Nguyen
Published: May 2021

Male infertility is a reproductive disease in men caused by multiple factors ranging from harmful lifestyle habits to endogenous genetic elements. This study aimed to investigate the association between the polymorphism AhRR rs2292596 and male infertility. Total DNA was extracted from blood of 422 Vietnamese samples including 218 non-obstructive azoospermic and oligozoospermic patients and 204 healthy controls. The genotypes of the polymorphism were determined by PCR-RFLP method. The distribution of genotypes and their relationship with male infertility were analyzed by statistical methods. The results indicated that rs2292596 AhRR followed Hardy-Weinberg equilibrium (p-value > 0.05). However, there was association between the rs2292596 polymorphism and male infertility in the three models (additive, dominant, and recessive) (p-value > 0.05). The investigation would help enrich the knowledge about the influences of genetic factors on male infertility in the Vietnamese population.
Extraction of polysaccharide from Spirulina platensis - advantage of freeze-thaw method
Authors: Thi Dong Phuong Nguyen , Van Anh Le Thi , Thi Dieu Huong Le , Thi My Yen Pham
Published: May 2021

Polysaccharide is one of the key natural products that profit human living conditions. This study aimed at investigating the polysaccharide extraction from Spirulina platensis (PSP) basing on previous research on optimization of experimental conditions. As a result, the efficiency of raw PSP for four extraction methods was 8.35%, 65%, 76.9% and 85.1% for hot water, lye, ultrasound-assisted and freeze-thaw extraction method, respectively, which was higher than previously reported results. Particularly, the efficiency of pure PSP extraction was highest with 14.89% of the dry matter of raw PSP for freezing-thawing method. To determine the major compounds constructing the pure PSP, the composition of PSP monosaccharides was determined by HPLC. The result showed that major PSP monosaccharides were glucose and galactose, of which glucose composition was up to 85%. Furthermore, pure PSP showed antioxidant activity with IC50 values of 373, 403, 276, and 258 mg/mL for hot water, lye, ultrasound-assisted, and freeze-thaw extraction method, respectively, as compared to IC50 of 101.7 mg/mL for ascorbic acid as control.
Konserwatyści krakowscy a zamach majowy. Ewolucja optyki działaczy Stronnictwa Prawicy Narodowejw stosunku do zamachu stanu z 1926 r.
Authors: Kwinta Katarzyna
Published: May 2021

Zamach majowy jest jednym z najbardziej kontrowersyjnych wydarzeń w historii niepodległej Polski. Józef Piłsudski, który głosił potrzebę „sanacji” czyli uzdrowienia państwa, 12 maja 1926 roku wraz z grupą tzw. piłsudczyków dokonał zamachu, w wyniku którego przejął władzę w stolicy. Dla konserwatystów był to czyn absolutnie niezgodny z prawem oraz sprzeczny z linią ideowa tej grupy. Dla zachowawców jednym z najistotniejszych elementów ideowych było pielęgnowanie tradycji i wprowadzanie zmianw oparciu o proces ewolucji a nie rewolucji. Grupa konserwatystów krakowskich początkowo negatywnie ustosunkowała się do zbrojnego przejęcia władzy przez piłsudczyków, co odzwierciedlały artykuły ukazujące się w ich krakowskim organie prasowym – „Czasie”. Wraz z posunięciami rządu po 1926 r. (m.in. utworzenie rządu na czele z Józefem Piłsudskim oraz uwzględnienie w gabinecie przedstawicieli grupy wileńskich zachowawców – „żubrów wileńskich”), optyka tego środowiska ulegała powolnej zmianie. Celem artykułu jest ukazanie procesu ewolucji jaki miał miejsce w wewnątrz grupy krakowskich zachowawców względem zamachu majowego -od skrajnie negatywnego podejścia do akceptacji a nawet nawiązania współpracy z obozem rządzącym po 1926 roku.
Building Information Modelling and Collaboration in the Nigerian Construction Industry
Authors: Onungwa Ihuoma Onyinechi , Uduma-Olugu Nnezi
Published: May 2021

Building Information Modeling (BIM) is a concept that is transforming the way construction is done internationally.  Nigeria is lagging behind in adoption of BIM as a collaborative tool amongst professionals in AEC industry.  The purpose of this paper is to study the adoption of BIM in Nigeria and determine to what extent it has helped in improving collaboration among consultants in Nigerian construction industry. The research methodology involved using structured questionnaires to 30 AEC firms selected through simple random sampling method.    Results showed BIM has a high impact on client satisfaction, time for completion, quality and presentation of different concepts in schematic design. It also showed high impact on conflict resolution, supervision, construction programming and quality of completed jobs during post contract stage. Barriers to adoption of BIM were identified as lack of infrastructure, lack of skilled workers and lack of awareness of technology. Discussion with peers showed that barriers to collaboration included lack of support from leadership in the offices and lack of belief in usefulness of the software.  For Nigeria to compete internationally in the construction industry, BIM should be adopted hence there is need for research on the subject. Recommendations include developing a curriculum that will incorporate the study of BIM in all construction courses.  Learning centers should also be developed for private practitioners. Efforts should be made by the relevant professional bodies to increase awareness of the technology. Incentives should be given to offices to encourage adoption and collaboration among consultants.
Cardiovascular Risk and Factors Associated to the Health in Hypertensive African Descent People Resident in Quilombola Community
Authors:   Universidade Estadual do Sudoeste da Bahia, Souza Rosa Randson , do Santos Ribeiro Ícaro José , da Silva Jaine Kareny , Rodrigues Souza Luiz Humberto , Pires Cruz Diego , Oliveira Damasceno Rudson , de Souza Junior Edison Vitório , Silva de Oliveira Boery Rita Narriman
Published: May 2021

Introduction: Hypertension is a cardiovascular risk factor of wide magnitude among people of African descent, especially those living in Quilombos. However, little is known about the factors associated with cardiovascular risk in residents of the urban Quilombola community. Objetive: To analyze the cardiovascular risk and health-related factors in the family context of hypertensive Afro-descendants living in an urban Quilombola. Materials and methods: It is a cross-sectional and community-based study carried out from November 2017 to March 2018. The study’s population consisted of 303 hypertensive patients enrolled in the family health unit, with ages ranging from 35 to 79 years old, of both genders; and using antihypertensive drugs. The instruments used for data production were: The Primary Arterial Hypertension Questionnaire and the Framingham Risk Score. Results: There was a significant association between cardiovascular risk and cardiovascular disease (CVD) family history (p<0.011), type II diabetes (p<0.001) and overweight and obesity (p<0.010). Conclusion. Research has shown that hypertensive Quilombola people have consistent cardiovascular risk outcomes, especially with CVD family history, type II diabetes, overweight and obesity, schooling and gender with significant associations.
Clúster de síntomas en insuficiencia cardiaca avanzada: una revisión sistemática
Authors:   Universidad El Bosque, Pérez Sandoval Leidy Paola , Moreno García Jenny Rocío , Barboza Galindo Adriana Paola
Published: May 2021

Introducción: La Insuficiencia cardiaca avanzada genera deterioro clínico y funcional marcado en el paciente. A través del tiempo se han desarrollado investigaciones para evaluar síntomas y aliviar el sufrimiento. El presente artículo tiene como objetivo identificar los clúster de síntomas en pacientes con insuficiencia cardiaca avanzada, que puedan contribuir en la consolidación del conocimiento. Materiales y Métodos: Una estrategia PICO estableció la pregunta clave de revisión desarrollada, mediante PRISMA, con búsquedas en: Scopus, Pubmed, Embase y Google Scholar. Se incluyeron artículos de fuente primaria, insuficiencia cardiaca avanzada, publicados 2010 – 2019 en inglés y español, se excluye población pediátrica. Se realizaron análisis descriptivos de los síntomas encontrados. Resultados: De 8000 estudios, fueron incluidos 11 para revisión completa, la mayoría de corte transversal, cuyas características de la muestra corresponde 50% hombres, entre 56 y 83 años. Se identificaron en el clúster físico síntomas: fatiga, dificultad para dormir, disnea; en el cluster emocional se identifican: Depresión, deterioro cognitivo y preocupación, además se encontró evaluación de síntomas por región geográfica. Discusión: Existe un consenso en la clasificación de síntomas en grupos denominados físico y emocional, llama la atención que el edema en algunos casos no está incluido en ellos. Limitaciones: Se incluyeron dos estudios del mismo autor en diferente año de publicación, población y los clúster son los mismos, pero con análisis de variables como calidad de vida y estado funcional. Conclusión: Diversidad de poblaciones, tipos de estudio y métodos de análisis, no permiten un único enfoque para agrupación de los síntomas más frecuentes en pacientes con insuficiencia cardiaca avanzada.
Cefuroxime imprinted p(HEMATrp) Cryogels: Preparation, Characterization and Antibacterial role
Authors: ASLIYÜCE ÇOBAN Sevgi , İDİL Neslihan , DENİZLİ Adil
Published: May 2021

Both Gram negative and positive bacterial strains are known as the most frequently responsible causative agents for wound infections. These infections can resulted in morbidity and mortality due to the severity. Antimicrobial agents have often been preferred to treat these infections. In this respect, Cefuroxime (CXM) belongs to the second-generation cephalosporins could be suggested against wound infections. In recent years, designing of drug delivery systems have received interest and cryogels are promising tools for creating these systems. Their elastic nature, high macroporosity, absorption and releasing ability make these materials unique for drug delivery. Besides, imprinting approach could be integrated into cryogelation and resultant matrix has an ability to recognize target antimicrobial agent having high selectivity and sensitivity prepared along with an easy and cost-effective methodology.

In the present study, CXM was imprinted onto Hydroxyethyl methacrylate (HEMA) based N‐methacryloyl‐l‐tryptophan (MATrp) containing [p(HEMATrp)] cryogels. MATrp was used as the co-monomer for the preparation of CXM-p(HEMATrp) cryogels. Characterization experiments were performed to analyze the structure of prepared cryogels. Following drug loading and releasing assays, antimicrobial performances CXM-p(HEMATrp) cryogels were investigated against Staphylococcus aureus, Enterococcus faecalis and Escherichia coli. In conclusion, CXM-p(HEMATrp) cryogels have been recommended as potential carriers for further biomedical applications.
Елеваторні потужності по областям України: Рейтинг за 2019 р.
Authors: Https://elevatorist.com Джерело:
Published: May 2021

У 2019 елеваторні потужності України, за даними Карти елеваторів сайту Elevatorist.com склали близько 51 млн т одноразового зберігання. У ці потужності входять фермерські, портові, примлимнові елеватори, а також зерносховища, для комбікормових заводів і ОЕЗів. З них на даний момент підлогові склади займають 35,7%, СОГі - 20,6%, металеві силоси - 43,7% від загального обсягу зберігання.
PECULIARITIES OF THE PROCESS OF PURIFICATION OF AMRANT GRAIN FROM IMPURITIES
Authors: Stankevych G. , Valentiuk N.
Published: May 2021

Proper and balanced nutrition is the key to a person's physical health, especially in the face of deteriorating environmental conditions and the effects of daily stress caused by the accelerated pace of life in recent years. In this regard, the attention of many researchers and entrepreneurs is focused on the development and implementation in mass production of foods that would fully meet human needs for protein, vitamins, micro-and micronutrients, etc. Recently, ingredients made from non-traditional vegetable raw materials have been used for the production of functional foods. Amaranth belongs to such vegetable raw materials. Amaranth culture has been known since ancient times, used by the ancient Aztecs. The main feature of this culture is the unique chemical composition, which causes an extremely wide range of its use, which is not limited to the food industry. In terms of amino acid composition, amaranth grain protein is close to the composition of an ideal protein. The presence of squalene in amaranth oil makes it possible to use it for the manufacture of medicines and cosmetics. However, despite the prospects for the use of amaranth, producers face difficulties with the characteristics of the grain of this crop. Small grain sizes require careful selection of mode parameters of technological equipment for post-harvest processing. To substantiate the cleaning regimes, a study of the particle size distribution, physical-mechanical and aerodynamic properties of amaranth grain mass has been carried out. Based on the research, it is established that despite the fact that some amaranth species like  shchyrytsya” have almost the same grain size and shape, the transgression coefficients calculated according to certain divisibility values can predict the possibility of separating a mixture of freshly harvested amaranth grain and its impurities, in particular from difficult to separate . It is proposed to use a set of sieves with round holes of the following sizes (mm) to separate this mixture: B1 – 1.0…1.1; B2 – 1.0…1.1; B2 – 1.0…1.2; G1 – 0.7…0.9; and elongated holes with dimensions (mm): B1 – (0.8…1.0)×20, B2 – (0.5…0.7)×20, B1 – (0.4…0.6)×20 .
OPTIMIZATION OF THE COMPOSITION AND PROPERTIES OF BAKERY PRODUCTS
Authors: Lakiza О. , Rudnіeva L. , Vinogradova V.
Published: May 2021

The article is devoted to the study of the properties of bakery products, in particular the choice of the optimal concentration of flaxseed cake in baguettes in order to ensure maximum caloric content. It is known that bakery products are necessary for a person to ensure his health and ability to work. The range of food products, in particular bakery products, is constantly growing. The analysis of the range of bakery products showed that the market is experiencing a shortage of flour products for dietary, therapeutic and prophylactic and special purposes for different groups, and their share in total production does not exceed 1-2%. The problem of food production is becoming more complicated and exacerbated by increasing consumption, declining natural resources of food raw materials and the presence of specific anti-nutrients. The article describes the characteristics of anticancer substances in food, which belong to the groups of hytosterols and lignans. The article presents the results of optimizing the composition and properties of wheat baguettes with the addition of linencake, flaxseed meal. The recipe of bread with the inclusion of linen cake in the amount of 1 to 15% was developed. The nutritionalvalue and caloric content of bread are calculated, its characteristics are given according to the main organoleptic indicators of quality (product surface, color and thickness of the crust, as well as the condition of the crumb). The effect of the percentage of flaxseedmeal on the moisture and acidity of bread samples was studied. It is established that with the increase of the content of flaxseed mealthe protein content increases, the carbohydrate content decreases, the fat content and the amount of unsaturated fatty acids increase.As the content of linen cake in bread increases, the amount of unsaturated fatty acids increases and its caloric content decreases, andits nutritional value increases. The use of flax seeds and products of their processing in the formulation of bakery and confectionery products can increase their biological value and physiological efficiency due to the content of anticancer substances, fibers, micro- and microelements, proteins and essential amino acids. Trial laboratory baking of baguettes showed that the optimal content of linen cake is 5% by weight of wheat flour, which allows you to get bread that meets the standards and does not require changes in technological parameters, which are set for the product without additives.
CHLORELLA SUSPENSION IN PIGS’ RATIONS
Authors: Karunskyi O. , Voroniuk Т. , Madani М.
Published: May 2021

The article covers addition of chlorella suspension, its effect on nitrogen balance, digestibility of nutrients and amino acids, pig productivity. Various feed additives, micro-element mixtures, and vitamins are used in animal nutrition to deal with the deficiency ofcertain vitamins and mineral elements in the rations. The peculiarity of chlorella suspension as a feed additive is in the ability to cultivate it throughout the whole year and in the availability of optimized technologies for its cultivation and use. Chlorella suspension is rich in proteins, minerals, vitamins, fatty acids and fiber. Introduction of chlorella suspension into pigs’ diets has helped to increase the digestibility coefficients of both inessential (by 7.5 %) and essential (by 2 %) amino acids. Feeding the animals with chlorella suspension has also resulted in the release of nitrogen retained in animals’ bodies by 13 % compared to the control group. The additional use of chlorella suspension in the diet of fattening pigs (large white) was found to increase the average daily gain by 21.9% compared to the control group which did not receive chlorella suspension. The conversion of animal feed to obtain 1 kg of live weight gain in the control group was 5.1 kg, in the experimental group - 4.2 kg, and the conversion rate of feed in the experimental group was higher by 21.4 %.Feeding young pigs with chlorella suspension increases the digestibility of protein by 4.5 %, fiber by 2.0 %, fat - 0.7 %, essential amino acids - 81.6 %. The introduction of chlorella suspension to pig rations leads to an increase in the level of nitrogen in their body by 54.7 %of that taken with feed and 69.15 % of that digested in the body. Pork production profitably using chlorella suspension stood at 12.3 % , which is more by 87,8 % compared to the control group.
Nursing training from the perspective of graduates
Authors: Guareschi Ana Paula Dias França , Freitas Maria Aparecida de Oliveira , Nunes Maria Inês
Published: May 2021

ABSTRACT Objective: To correlate the satisfaction of graduates with their training according to their professional characteristics and general competences. Method: Descriptive cross-sectional study with a sample of 192 Nursing graduates from a private higher education institution in the city of São Paulo. Data were collected between 2016 and 2017. Results: Graduates placed in the job market within one year (p=0.01) had nursing as their main source of income (p=0.011) and occupation (p=0.014); those who considered themselves professionally successful and those who would choose the profession again (p=<0.001), if they could choose, were more satisfied with their training. Satisfaction with training was linked to the competences acquired during graduates’ training, such as decision making (p=0.002), leadership (p=0.004) and continuing education (p=0.005). Conclusion: The study shows that most graduates consider their training satisfactory when analyzed with the study variables.
INTEGRAÇÃO DE TECNOLOGIA NA EDUCAÇÃO: PROPOSTA DE MODELO PARA CAPACITAÇÃO DOCENTE INSPIRADA NO TPACK
Authors: SILVA JUAREZ BENTO DA , BILESSIMO SIMONE MEISTER SOMMER , MACHADO LETICIA ROCHA
Published: May 2021

RESUMO: A integração tecnológica geralmente é entendida como a incorporação de tecnologia nas salas de aula. No entanto, um dos pontos que merece mais atenção é a forma como essa inclusão tem sido feita no processo de ensino, nas experiências de aprendizagem e no currículo. Assim, é possível afirmar que a integração das Tecnologias de Informação e Comunicação (TIC) na sala de aula envolve competências específicas dos docentes em relação ao uso pedagógico das tecnologias. Os professores devem adquirir e desenvolver continuamente conhecimentos, habilidades e atitudes pertinentes à área no intuito de incluir os recursos tecnológicos em suas tarefas diárias. Este estudo abordou a etapa inicial de um framework de integração de tecnologia na educação, que é parte do Programa de Integração de Tecnologia na Educação, desenvolvido pelo Laboratório de Experimentação Remota, na Universidade Federal de Santa Catarina. Neste estágio específico, conduziu-se uma pesquisa com o objetivo de conhecer o nível de conhecimento e experiência dos docentes participantes no que se refere ao uso de TICs em suas aulas. Dois questionários, disponibilizados no Ambiente Virtual de Ensino e Aprendizagem, foram respondidos por 398 professores de cinco escolas durante o estágio inicial das capacitações ofertadas pelo programa entre 2017-2019. Este estudo permitiu conhecer a visão dos docentes participantes quanto ao uso de tecnologias. É possível afirmar que o framework de formação tem se mostrado eficiente, uma vez que tem possibilitado aos professores aprenderem a utilizar as tecnologias em sala de aula bem como a refletir sobre as suas próprias práticas pedagógicas.
Trichinella spiralis in a cougar (Puma concolor) hunted by poachers in Chile
Authors: Echeverry Diana Maritza , Santodomingo Adriana Milena Santodomingo , Thomas Richard Said , González-Ugás Jorge , Oyarzún-Ruiz Pablo , Fuente María Carolina Silva-de la , Landaeta-Aqueveque Carlos
Published: May 2021

Abstract Trichinellosis is a zoonosis caused by nematodes of the Trichinella genus, of which 10 species have been described. Species identification when larvae is found is only possible using molecular tools. Meat from pigs and game animals not subjected to veterinary inspection are the main sources of human infections. The hunting of native carnivores is prohibited in Chile due to conservation issues and the fact that those animals favor pest control. The illegal hunting of a cougar (Puma concolor) occurred in September 2020. Herein, the molecular identification of Trichinella larvae, by analyzing nuclear (expansion segment V) and mitochondrial (cytochrome C oxidase subunit I) sequences are described. Both the amplification of the expansion segment V region and the phylogenetic analysis of a segment of a fragment of the cytochrome c-oxidase subunit I sequence confirmed that the larvae belonged to T. spiralis. The case described herein represents the first evidence of illegal hunting of a protected mammal infected with Trichinella in Chile, highlighting the ‘One Health’ perspective to face this disease in the rural-sylvatic interphase.
Fabrication and characterization of bioactive nanoemulsion-based delivery systems
Authors: Yilmaz Azime , Meral Raciye , Kabli Mohammad , Ermis Ertan , Akman Perihan Kubra , Dertli Enes , Taylan Osman , Sagdic Osman , Yilmaz Mustafa Tahsin
Published: May 2021

In this work, a nanoemulsion-based delivery system was developed by encapsulation of different concentrations (0.50%, 0.75% and 1.00% v/v) of oregano essential oil (OEO) within poly(vinyl alcohol). The delivery systems (OEO-loaded nanoemulsion systems (NESs)) were characterized in terms of size distribution, zeta potential and thermal, molecular, microstructural and antifungal properties. The average droplet diameter values were determined to be within the range 70–75 nm, while zeta potential values within the range 3.13–19.90 mV were recorded. An increase in the OEO concentration did not affect the size distribution of nanoemulsions. Change in the concentrations showed no visible differences in Fourier transform infrared spectra. However, for concentrations of 0.50, 0.75 and 1.00%, endothermic peak temperatures were recorded as 94, 105 and 117°C, respectively. The antifungal activity of NESs against the mycelial growth of Aspergillus niger was evaluated, revealing a significant enhancement in the antifungal activity in comparison with that of free OEO. The zone diameter of mycelial growth could be reduced by around 20, 55 and 65% using NESs at levels of 0.50, 0.75 and 1.00% v/v, respectively, over 6 days of incubation. The results of this study revealed the stronger antifungal efficiency of OEO by its encapsulation into NESs as compared with that of free OEO.
Concept of Majja Dhatu of Ayurveda in Perspective of Bone Marrow: A Review
Authors:   M.D. Scholar, Kriya Sharir, CBPACS, New Delhi, India., Ritesh  , Barla Manjry Anshumala ,   Senior Medical Officer (Ay.), Directorate Of Ayush, Govt. Of NCT Of Delhi., Roushan Rakesh ,   Assistant Professor, Kriya Sharir, CBPACS, New Delhi, India.
Published: May 2021

Ayurveda has described three basic physiological constituent dosha, dhatu and mala for the existence of human body. Among them, seven dhatus form the structural units of the body. The functions of dhatus are dharana (to support) and poshan (to nourish). Dhatus undergo continuous construction and degeneration to maintain a state of equilibrium of the body. Majjadhatu is the sixth dhatu to be formed after asthi dhatu in uttrottardhatuposhan cycle. Bone marrow can be considered as a part of majja dhatu playing a significant role in erythropoiesis. Acharya Sushrut has mentioned about saraktameda and majja. Asthi (bone) and sandhi (joints) are the foundation of majjavahasrotas. The quantity of majjadhatu is one anjali. This manuscript is an attempt to explore the physio-anatomy of majja dhatu based on physiological functions described in ayurveda classics. For which the basic material has been collected from the ancient classics with the available commentaries as well as text books of contemporary modern medical science. KEY WORDS: Bone Marrow, Majja, Majjavahasrotas, Medas, Saraktameda.
Incidence of Mortality rates due to Tuberculosis in Association of South East Asian Nations and its relation to Current Health Expenditure Per Capita: A secondary Data Analysis
Authors:   Medical student, Perdana University-Royal College of Surgeon’s in Ireland School of Medicine (PU-RCSI), Perdana University, Kuala Lumpur, Malaysia., Ahmed Laila Ayman , K Shetty Jeevan ,   Department of Biochemistry, Perdana University-Royal College of Surgeon’s in Ireland School of Medicine (PU-RCSI), Perdana University, Kuala Lumpur, Malaysia., Thirupathirao Vishnumukkala ,   Department of Anatomy, Perdana University-Royal College of Surgeon’s in Ireland School of Medicine (PU-RCSI), Perdana University, Kuala Lumpur, Malaysia., R. Naik Venkatesh ,   Department of Pathology, Perdana University-Royal College of Surgeon’s in Ireland School of Medicine (PU-RCSI), Perdana University, Kuala Lumpur, Malaysia.
Published: May 2021

Introduction: Tuberculosis is a devastating health condition with a high incidence in the ASEAN population. This study analyses mortality trends due to TB among the Association of South East Asian Nations (ASEAN) and also investigates the relationship between mortality and Current health expenditure (CHE) per capita Methods: This study is a secondary data analysis on mortality rates and CHE per capita from the year 2002 to 2017. The data was obtained from global health observatory data repository databases and World Bank Organization respectively. They were analysed using SPSS trial version 23. Results: This study showed an overall reduction in mortality rates among the ASEAN countries except Brunei Darussalam which showed an increase. This study also showed an indirect intermediate correlation between mortality rates and CHE per capita. Discussion: Among the ASEAN, Singapore, which follows the TB control program suggested by WHO, achieved 2/5 TB control performance indicators. Its healthcare spending has almost doubled since 2010. Since implementation of directly observed treatment, short-course in Thailand in 2001, Thailand has succeeded achieving the detection target. Brunei Darussalam witnessed an increase in mortality rate. The rise in the number of people with chronic Non –communicable Diseases, especially diabetes mellitus, is posing a major challenge to Brunei's TB control efforts. Myanmar has a heavy TB burden, it seeks to cut TB incidence in half by 2025. Key words: Tuberculosis , ASEAN, Secondary data analysis, Mortality, Current health expenditure per capita.