bluuebunny/crossref_metadata_2025 huggingface dataset:
İPLİĞİ BOYALI PAMUKLU KUMAŞLARDA AĞARTMA İŞLEMİNİN MUKAVEMETE VE RENK FARKINA ETKİSİNİN İNCELENMESİ
Authors: ŞİMŞEK GÜNDÜZ Gonca , AKARSLAN KODALOĞLU Feyza
Published: December 2023

Günümüzde ekolojik ve ekonomik üretim çok daha fazla önem kazanmıştır. Klasik ağartma yöntemlerinin su ve enerji kullanımının yüksek olması nedeniyle ekolojik ve ekonomik açıdan incelenmesi gerekmektedir. Ayrıca ağartma işleminde tekstil materyaline zarar vermeden istenilen rengin elde edilmesi de önemlidir. Çalışmada ağartmalı ve ağartmasız proses ile iki farklı renkte boyanan ipliklerden kumaş dokunmuştur. Kumaşların kopma mukavemeti ve yırtılma mukavemeti ölçülmüş, ağartmalı ve ağartmasız boyama prosesleri arasındaki fark istatistiksel olarak analiz edilmiştir. Ağartma işlemi yapılarak boyanan ipliklerden elde edilen kumaşların kopma ve yırtılma mukavemetlerinin istatistiki olarak daha düşük olduğu görülmüştür. Ayrıca ağartmasız boyama prosesi ile boyanan ipliklerden üretilen iki farklı renk kumaşın renk farkı değerleri incelenmiştir. Koyu renkli kumaşlarda ölçülen renk farkı değeri kabul edilebilir aralıkta çıkmıştır. Açık renkli kumaşlarda ölçülen renk farkı değeri kabul edilebilir aralığın dışında çıkmıştır. Özellikle açık renkli boyamalarda klasik ağartma yöntemleri dışında, tekstil materyaline zarar vermeden istenilen rengin elde edildiği, ekonomik, ekolojik ve sürdürülebilir ağartma yöntemlerinin geliştirilmesi gerekmektedir.
KATI YAĞLAYICI OLARAK GRAFİT KATKILI NAYLON 6 KOMPOZİTLERİN MEKANİK VE TRİBOLOJİK PERFORMANSLARI
Authors: ÜNAL Hüseyin , YETGİN Salih Hakan , ÜNAL Veysel Furkan
Published: December 2023

Bu çalışmada saf naylon 6 polimeri ile farklı oranlarda grafit (Gr) katkılı naylon 6 polimer esaslı kompozitlerin mekanik ve tribolojik performansları incelenmiştir. Ağırlıkça %5-10-15 gibi farklı oranlarda grafit katkılı kompozitler üretilmiştir. Granüller kompound üretim yöntemiyle üretilirken mekanik ve tribolojik test numuneleri enjeksiyonla kalıplama yöntemiyle basılmıştır. Üretilen kompozitlerin sertlik, çekme mukavemeti, kopmadaki % uzama ve elastiklik modülü gibi mekanik özellikleri ile sürtünme katsayısı ve aşınma oranı gibi tribolojik özellikleri incelenmiştir. Tribolojik deneyler, 0,5 m/s kayma hızında ve 30 N yükte gerçekleştirilmiştir. Tribolojik özellikler naylon 6/naylon 6 çifti, naylon 6-5Gr/naylon 6-5Gr, naylon 6-10Gr/naylon 6-10Gr ve naylon 6-15Gr/naylon 6-15Gr kompozit çiftlerinin birbiri üzerinde çalışması durumunda gerçekleştirilmiştir. Çekmedeki elastiklik modülü ve sertlikte artışlar gözlenirken çekme mukavemeti, kopmadaki % uzama değerlerinde azalma tespit edilmiştir. En yüksek elastiklik modülü 4607 MPa ve en yüksek sertlik 77 Shore D değeri ile %15 oranında grafit katı yağlayıcı katkı içeren Naylon 6 polimer kompozitinde elde edilmiştir. En düşük çekme mukavemeti ve kopmadaki % uzama değerleri ile en düşük aşınma oranı ve en yüksek sürtünme katsayısı %15 grafit katkılı naylon 6 polimer kompozitinde elde edilmiştir. Naylon 6-15Gr/naylon 6-15Gr kompozit çiftinin sürtünme katsayısı naylon 6/naylon 6 çiftine göre yaklaşık %63,8 oranında artmıştır. Nylon6/nylon6 ile karşılaştırıldığında, nylon6-5Gr/nylon6-5Gr kompozitin, nylon6-10Gr/nylon6-10Gr kompozitin ve Nylon6-15Gr/nylon6-15Gr kompozitin aşınma oranları sırasıyla %30,8, %51,7 ve %56,3 azalmıştır.
SENTINEL-2 MSI VE LANDSAT-9 OLI UYDU GÖRÜNTÜLERİYLE YANMIŞ ALANLARIN TESPİTİ: 2022 MUĞLA/MARMARİS ORMAN YANGINI
Authors: YÜCER Emre
Published: December 2023

Orman yangınları canlılara ve bitki örtüsüne zarar vermekte, bunun yanında hava kirliliğine de neden olmaktadır. Bu nedenle orman yangınlarıyla mücadele önemli bir durum olarak karşımıza çıkmaktadır. Günümüzde gelişen teknoloji sayesinde görüntü işleme algoritmaları ve uzaktan algılamadaki farklı indeksler kullanılarak uydu görüntülerinden yanan alanların tespiti yapılabilmektedir. Bu çalışmada 21 Haziran 2022 tarihinde Muğla ili Marmaris ilçesinin Küfre koyu ve Hisarönü mahallesinde meydana gelen orman yangını Sentinel-2 MSI ve Landsat-9 OLI uydu görüntüleriyle analiz edilmiştir. Bu amaçla çalışma alanına ait yangın öncesi ve sonrasında ait uydu verilerinden Normalleştirilmiş Fark Bitki İndeksi (Normalized Difference Vegetation Index-NDVI), Normalize Edilmiş Nem İndeksi (Normalized Moisture Index-NDMI), Normalize Edilmiş Yanma Oranı İndeksi (Normalized Burn Ratio Index-NBRI) ve Yanmış Alan İndeksi (Burned Area Index-BAI) hesaplanmıştır. Analizler sonucunda elde edilen yanmış alanlar Orman Genel Müdürlüğü (OGM) verileri ile karşılaştırılmıştır. Bu karşılaştırma sonucunda OGM değerlerine en yakın sonuçların; Landsat-9 OLI görüntüsünde NDMI ve Sentinel-2 MSI görüntüsünde NDVI indekslerinin olduğu tespit edilmiştir. Sınıflandırma sonuçlarını değerlendirmek için hata matrisi hesaplanmıştır. Genel doğruluk ve Kappa değerlerine göre Sentinel-2 MSI görüntüsü, Landsat-9 OLI görüntüsüne göre daha yüksek değerlere sahip olduğu tespit edilmiştir. Sentinel-2 MSI görüntüsünde 0,99 genel doğruluk ve 0,98 Kappa değeri ile NBRI indeksi en yüksek değerleri elde etmiştir.
AN EXPERIMENTAL INVESTIGATION OF THE SPEED LOSSES IN POLY-V BELT SYSTEMS ON HOUSEHOLD DRYERS
Authors: MUTLUDOGAN Mehmet , BOLAT Berna , AŞÇIOĞLU TEMİZTAŞ Birgül
Published: December 2023

A decrease in rotational speed in gear belt systems is one of the fundamental problems that affects the efficiency of the belt. Therefore, in this study, the speed loss behavior of a Poly-V gear belt drive system with two different designs has been experimentally investigated. In the study, experiments were conducted with two different home-type dryers; one used two belts and a stepped pulley to adjust the speed, while the other used a single belt to reach the required speed. The experimental studies were conducted with two different home-type dryers. The results were analyzed using statistical methodology to determine whether the normal distribution was suitable for the measurement results, and a pairwise comparison of the speed losses in the two systems was made. Additionally, the predicted formula for loss calculation was compared with the results of variance analysis (ANOVA), and it was found that very similar results were obtained. As a result of the experimental study and analysis, it was observed that the single-belt drive system is more efficient compared to the two-belt drive system. With the efficiency curve obtained from this study, it is possible to calculate speed loss and efficiency gain for similar belt drive systems.
STM32F407 VE NODEMCU ESP8266 KARTLARI KULLANARAK KABLOSUZ ÇOK YÖNLÜ KONTROLLÜ ROBOTİK ARAÇ SİSTEMİNİN GELİŞTİRİLMESİ
Authors: ACUN Muhammet Fatih , DALDAL Metehan , AVCI Kemal
Published: December 2023

Bu çalışma, kablosuz uzaktan çok yönlü olarak kontrol edilebilen üç tekerlekli bir robotik aracın gerçekleştirilmesini amaçlamaktadır. Sistem, Türkçe sesli komutlar ve dokunmatik butonlar kullanarak, bilgisayarlar ve mobil akıllı telefonlar aracılığıyla hem internetsiz hem de internetli olarak kontrol edilebilen bir yapı sunmaktadır. STM32F407 tabanlı ilk çalışmada, Bluetooth üzerinden bilgisayar tabanlı olarak butonlu ve sesli komutlarla robotik aracın kontrolü yapılmış, bu doğrultuda Tkinter tabanlı bir kullanıcı arayüzü oluşturulmuştur. Sesli komutların internetsiz olarak algılanabilmesi için, öncelikle 5 Türkçe komutun bilgisayar ortamında doğru tanınması için Mel-Frekans Kepstral Katsayıları (MFCC) öznitelik çıkarma işleminde ve Dinamik Zaman Bükmesi (DTW) yöntemi de eşleştirme ve karar verme işleminde kullanılmıştır. 15 katılımcıdan 5 sesli komut için örnekler alınmış ve kullanılan yöntem test edilmiştir. Sonuçlar 5 sesli komutun %100 doğrulukla tanındığını göstermiştir. Daha sonra STM32F407 tabanlı akıllı telefon ve Bluetooth temelli kontrol çalışması ele alınmış ve sesli komutlar için Google asistan tabanlı çalışan bir mobil arayüz tasarlanmıştır. Üçüncü ve dördüncü çalışmalar ise NodeMCU kartı kullanarak sırasıyla Bluetooth ve Wi-Fi bağlantılar üzerinden aracın kontrollerini içermektedir. Nesnelerin interneti temelli kontrol için Arduino IoT Cloud tabanlı bir arayüz geliştirilmiştir. 10 katılımcıyla yapılan gerçek zamanlı çalışmalar, STM32F407 ve NodeMCU kartları tabanlı tüm kontrol yöntemlerinin başarılı bir biçimde çalıştığını göstermiştir.
EKLEMELİ İMALAT TEKNOLOJİSİNİN DEMİRYOLU ENDÜSTRİSİNDE KULLANIMI ÜZERİNE BİR DERLEME
Authors: ASLAN İbrahim , CAN Ahmet
Published: December 2023

Eklemeli imalat, geleneksel üretim yöntemlerine göre nesnelerin katman katman üretildiği yenilikçi bir yöntemidir. Son yıllarda eklemeli imalatın kullanım alanları hızla artmaktadır. Bu imalat yönteminin birçok sektörde olduğu gibi demiryolu sektöründe de kullanım potansiyeli yüksektir. Demiryolu endüstrisinde eklemeli imalatın genel olarak; demiryolu altyapısında ve demiryolu üstyapısında, demiryolu araçlarında kullanıldığı görülmektedir. Eklemeli imalatın özellikle parçaların özelleştirilmesine olanak tanıması, karmaşık parçaların üretimi ve tasarım özgürlüğü, hızlı prototipleme, malzeme tasarrufu, düşük üretim maliyeti gibi avantajları, demiryolu endüstrisinde ve diğer endüstrilerde kullanımının yaygınlaşmasına olanak sağlamaktadır. Eklemeli imalatın malzeme sınırlamaları ve üretim hızı gibi bazı sınırlamaları olsa da, bu avantajların sunduğu imkanlar birçok alanda yeniliği teşvik etmektedir. Bu çalışmayla, demiryolu endüstrisi ve eklemeli imalat hakkında genel bilgiler verilmiştir. Ayrıca, eklemeli imalatın demiryolu endüstrisinde kullanımı ve kullanıldığı alanlar hakkında inceleme yapılmıştır. Çalışma sonucunda, araştırmacılar için eklemeli imalatın demiryolu endüstrisinde hangi alanlarda kullanıldığı, hangi alanlarda ise kullanımının eksik olduğunun görülmesi ile kullanım alanının geliştirilmesi sağlanmaya çalışılmıştır.
The Essence of Administrative Prejudicial Effect as a Legal Phenomenon
Authors: Laktyukhin A. O.
Published: December 2023

One of the modern trends in the development of criminal legislation in Russia is manifested in an increase in the number of norms with administrative prejudicial effect. Such norms are enshrined in most chapters of the Criminal Code of the Russian Federation, which emphasizes their importance for the legislator. In these conditions, there is no doubt that for the correct application of these norms it is necessary, first, to correctly interpret the essence of administrative prejudicial effect, to understand its main purpose and characteristics. Today in criminal law there is no legal interpretation of this term, which leads to the emergence of ever new approaches to the definition of administrative prejudice in criminal law. However, they do not fully reveal its essence, but only touch on its individual features. A particularly fundamental point that emphasizes the importance of identifying the legal nature of administrative prejudicial effect is that in science there are ongoing debates regarding the admissibility of such norms in criminal law in principle. In the absence of unity in the terminology used, the legislator also proposes different ways to consolidate administrative prejudicial effect in criminal law. The logical result of such an ambiguous approach to the formulation of crimes with administrative prejudicial effect is the difficulty in interpreting the elements of such crimes. At the same time, it is obvious that these criminal law norms, due to the unity of their legal purpose, must be established uniformly. Uniformity should be manifested both in the use of uniform terminology and in the application of the same approach to the construction of such crimes. In this regard, it is relevant to search for an integrated approach to establishing the essence of administrative prejudicial effect as a special criminal legal phenomenon.
Ukrainian Immigration to Poland
Authors: Leska-Ślęzak Joanna
Published: December 2023

The aim of the article is to analyse the immigration of Ukrainians to Poland against the background of changing migration policy. It contains the thesis that changes in Polish migration policy are a consequence of demographic problems as well as those related to the needs of the labour market. Numerous legal regulations facilitating Ukrainian immigrants’ settlement and work in Poland have been introduced since 2015. Poland’s openness to visitors from Ukraine after the outbreak of the war on its territory was confirmed in the Act of 12 March 2022 on assistance to Ukrainian citizens in connection with the armed conflict on the territory of that country. Currently, there are approximately 3.2 million Ukrainians in Poland, including 2.2 million in the areas of the Union of Metropolises of Polish Cities.
Contemporary International Significance and Commemoration of the First European Constitution of 3 May 1791 – with Particular Focus on Poland, Lithuania, Ukraine, Belarus and Latvia
Authors: Kubicki Radosław
Published: December 2023

The aim of the article was to examine the scope, forms, role and perception of the contemporary international impact of the historical event, which was the adoption of the Constitution of 3 May 1791. The conducted research allowed for a positive verification of the formulated hypothesis that the commemoration of the traditions of the May Constitution may constitute an important element of the Polish historical policy shaping the international image of Poland as a country that has made a significant contribution to the development of law in Europe and in the world. Answering the main research question, it was concluded that the tradition of the Third of May celebrations may constitute a common heritage and a platform for cooperation between the states whose territories were part of the First Republic, i.e. Poland, Lithuania, Ukraine, Latvia and alternatively Belarus. It was pointed out that annual celebrations connected with the Constitution take place primarily in Poland, the United States and recently also in Lithuania. It was also shown that the May Constitution is one of the best known fundamental laws in the world. The article is based on own research with the use of survey technique and scientific methods: historical, institutional-legal and statistical.
Military Conflict in Ukraine and Its Economic Impact
Authors: Rosłon-Żmuda Joanna
Published: December 2023

The purpose of the article is to show that the world of politics is inextricably linked with the economic sphere, and that political decisions have a huge impact on the economic environment regardless of whether they are made in peacetime or during ongoing conflicts. The current armed conflict in Ukraine shows vividly how the pursuit of Russia’s strategic goals, which are contrary to the principles and norms of international law and threaten world peace, unites Western countries in making decisions aimed at forcing Russia to revise its actions. These decisions have an economic dimension to the greatest extent, because economic sanctions in the absence of military engagement are the only tool in the hands of the West. Sanctions as a means of exerting pressure change the conditions under which the economies of both the sanctioned and the imposing entities operate. The severity of sanctions depends largely on their size and duration. In addition, sanctions automatically trigger so-called market effects that can be felt universally in the global market economy. The following research methods were used in the study: analysis of the Polish-language literature, descriptive method, statistical method.
Electoral System Changes in Austria – an Assessment of the Political Consequences
Authors: Miecznikowska-Jerzak Justyna
Published: December 2023

The analysis developed in this paper addresses the changes that took place over the years in the Austrian election and parliamentary scene following the succession of changes in the election law. The paper discusses the amendments to the National Council Election Regulation that came into force in 1970, 1992, and 2007. Using qualitative and quantitative parameters, it shows the transformations the federal party system was subjected to, exploring the political consequences of the voting system change. The paper focuses on assessing the changes that occurred in the election and parliamentary scene after 2007, when 16-year-olds were granted voting rights and postal voting was introduced. The reflections presented in this paper aim to provide an insight into whether amending the National Council Election Regulation put a stop to the falling voter turnout, gauge what the election participation of the youngest electorate was, identify what political decisions teenage voters made and examine what changed in the Austrian party system.
”Butchers’ Gazette” – a Gazette Not Only for Butchers
Authors: Wałachowska Teresa
Published: December 2023

In the early 20th century, Poznań, which belonged to the Prussian partition, was the leading press center. The professional press, which was developing at that time, was well represented. One of the professional magazines which were published in the Polish language was “Gazeta Rzeźnicka” [“Butcher’s Gazette”] – the first periodical for this vocational group. It was published from 1914 through the period of world war I, probably until the end of 1918. First, it appeared several times a week, later as a weekly. It was published, financed and edited by Apolinary klóskowski. An attempt to present the periodical, its formal, editorial and substantive analysis, is based on two preserved annual bound volumes: 1914 and 1918.
Adaptation of the Functionality of the Primo VE Search Engine to the Needs of Users of the University of Maria Curie-Skłodowska Library Catalog
Authors: Zielińska Urszula Maria
Published: December 2023

The article discusses configuration changes of the default settings of the Primo Ve search engine, using tools available from the Alma system. It presents search solutions tailored for users of the catalog of the Maria Curie Skłodowska University Library in Lublin. transparent access to the information about the traditional and electronic collections held was the main assumption of the work related to the configuration of the Primo Ve search engine. During the necessary configurations and adjustments, efforts were made to ensure that the presented system functions provided the user and all agendas of the UMCS library and information system with consistent information.
Roles of Languages and Technology in Teaching in Marginalised Communities: Perspectives and Practices
Authors: Kukulska-Hulme Agnes , Dawadi Saraswati , Giri Ram Ashish , Devkota Kamal Raj , Khan Rubina , Gaved Mark
Published: December 2023

Teachers in marginalised communities are known to face numerous challenges that may impact on their classroom practices. However, very little is known about their classroom practices in terms of their use of language and technology. Drawing on data collected in an international research project involving teachers and schoolchildren in several marginalised communities in Bangladesh, Nepal, Senegal and Sudan, the paper reports and reflects on the roles of languages and technology in education from the perspectives of teachers. The research data pertaining to teachers was collected through interviews and classroom observations and analysed through the lens of activity theory. Contradictions emerged between official languages used in class and the need to use local languages to support understanding, communication and discussion. Digital tools for teaching and learning were highly valued but scarce, consequently some teachers filled the gap by using their own digital and financial resources. Despite some challenges using English with students, teachers’ attitudes towards English were positive due to the perceived value of English for employment, access to information and social status. The research contributes to renewed awareness of marginalization and inequity and to promoting inclusivity. It contributes insights directly from communities that have not been studied from the combined perspective of languages and technology use in education. We discuss the implications of the findings for the improvement of pedagogical practices in marginalised communities.
Teacher as the Creator of Educational Space of Support and Development of Students’ Abilities and Talents
Authors: Popławska Agata , Bocharova Olena , Melnik Inesa
Published: December 2023

The article considers categories of abilities and giftedness. The characteristic of gifted students is presented. The question of creating conditions for the development of abilities and talents is revealed, and the role of the teacher as the creator of the space of support and development of students’ abilities and talents is pointed out. The basic elements of didactic system are described, i.e. goals and tasks of education, content, methods, means, organizational forms of educational space training, which promotes the development of abilities and talents. Moreover, the role of a teacher and a student in the process of teaching and learning is depicted.
The Neighborhood Effect on Perceptions of Corruption: Comparative Spatial Autocorrelation Analysis
Authors: Okunev I. , Zakharova E.
Published: December 2023

This article aims to investigate the factors influencing the perception of high corruption levels in a country and examines the potential existence of spatial dependence in the distribution of these factors. It specifically focuses on exploring the interdependence between the Corruption Perception Index (CPI) and forty four other factors categorized into six distinct categories. The central hypothesis posits that the interdependence between the CPI and these factors is more pronounced at the domestic level compared to its influence on indicators in neighboring countries. To assess the degree of interdependence between the CPI and each of the other indicators, the Pearson's Coefficient of Determination is employed, enabling an evaluation of corruption levels based on domestic state-specific factors. Furthermore, Moran's Bivariate Spatial Autocorrelation Index is utilized to elucidate the extent to which the CPI in one country influences one of the forty-four indicators in neighboring countries. Additionally, the Index of Spatial Interdependence is employed to ascertain the significance of domestic and international factors for each indicator. The research findings provide several noteworthy conclusions. Firstly, the neighborhood effect proves to be particularly significant for indicators that hold universal relevance for all governments, such as demographic and standard of living indicators. Conversely, indicators influenced by institutional, historical, and cultural differences exhibit stronger interrelations within the state. Lastly, the study establishes that the Pearson's Index holds greater significance than the Bivariate Moran's Index of Spatial Autocorrelation and the Index of Spatial Interdependence, thereby confirming the proposed hypothesis.
Structure and Reactivity of Halogenated GC PNA Base Pairs – A DFT Approach
Authors: Rajamani Ranjithkumar , K Indumathi , P Srimathi , G Praveena , Wong Ling Shing , Djearamane Sinouvassane
Published: December 2023

The present study explored the structural and reactivity relationship of halogenated G-C PNA base pairs using density functional theory (DFT) calculations. The halogens such as F, Cl, and Br are substituted by replacing H atoms involved in H-bonds of the base pairs. All structures were optimized using the B3LYP/6-311++G** theory level, and positive frequencies confirmed their equilibrium states. To understand the structural variations of the considered halogenated systems, the bond distances of R─X, R─H, and X/H•••Y and the bond angles of R─X•••Y were analyzed. The obtained structural parameters and interaction energies are comparable with the previous theoretical reports. In addition, the interaction energies (Eint) and quantum molecular descriptors (QMD) are also calculated to understand the difference between halogenated PNA systems and their non-halogenated counterparts. In this study, the enhancement in the reactivity properties  of halogenated PNA systems has been demonstrated, which indicates their improved responsive characteristics in various chemical reactions. Based on the available results, the halogenated PNA systems, carefully considering their substitutional position, facilitate better accommodation for the triplex formation of dsDNA/dsRNA. Therefore, it is concluded that the improved reactivity properties of halogenated PNA base pairs would make them potential candidates for various biological applications.
Identification and antibiotic susceptibility profiles of anaerobic bacteria isolated from patients with acne vulgaris
Authors: Walid Salma , Subramaniam Geetha , Sivasamugham Lalita Ambigai , Shing Wong Ling , Gunabalasingam Preamala , Ramli Nurfara Ain Binti , Visayaragawan Nithiya , Lian Gan Li , Agarwal Anshoo
Published: December 2023

Commensal bacteria like the Staphylococcal species are part of the skin microbiota, which helps maintain healthy skin. However, certain factors can lead to these commensals becoming opportunistic pathogens capable of causing diseases like acne vulgaris. Topical and systemic antibiotics have been the main treatment for acne. However, long-term antibiotic usage could result in the emergence of resistant bacterial strains and treatment failure. This study evaluated the antibiotic susceptibility patterns of anaerobic bacteria isolated from clinical acne samples. Skin swabs were collected from 50 acne patients and cultured under anaerobic conditions. The resulting bacterial isolates were identified using biochemical tests and 16S rRNA gene sequencing. The antibiotic susceptibility patterns of the confirmed isolates were determined using the disc diffusion assay for eight commonly prescribed antibiotics for acne treatment. Sequencing results revealed that S. epidermidis was the most isolated bacterial species (68%, n=34), followed by S. aureus (8%, n=4). However, a significant proportion of bacterial isolates were susceptible to all eight tested antibiotics, which is unusual. On the other hand, 26% (n=13) of the tested bacterial species isolates were found to be resistant to clindamycin, while 36% (18) were resistant to erythromycin and 20% (n=10) were to tetracycline. Since there has been limited research regarding the antibiotic resistance patterns of anaerobic acne-associated bacteria in Malaysia, this study can help shed some light on suitable local prescription practices and raise awareness about the cautious use of antibiotics in treating acne vulgaris.
Effect of Blumea Balsamifera Extract on the Kinetics of Calcium Oxalate Monohydrate (COM) Dissolution
Authors: Montealegre Charlimagne M. , Chan Louise Nicholle C. , Peralta Shaun Vincent P. , So Sven Eldric T.
Published: December 2023

Blumea balsamifera is a commercially available herbal drug that has anti-urolithic and diuretic properties. This study quantifies the effect of B. balsamifera extract on the dissolution kinetics of Calcium Oxalate Monohydrate (COM) crystals by modeling the dissolution of Ca2+. COM dissolution follows a first-order diffusion-controlled process. The extract did not change the dissolution phenomena. At 10 ppm, the extract had no significant effect on the rate constant (P = 0.166) and surface concentration (P = 0.372). Increasing the extract to 20 ppm did not change the dissolution phenomena and model parameters. The extract significantly decreases the equilibrium Ca2+ concentration with P = 0.0010 and P = 0.0179 at 10 and 20 ppm of extract, respectively. B. balsamifera extract binds free Ca2+ in the synthetic urine. This increases the amount of Ca2+ that dissolves but does not significantly increase the rate of dissolution suggesting that urine volume is more important for COM stone dissolution.
Clinic-o-etiological profile of cholestasis in infants in a tertiary care center
Authors: Kumar K. Pradheep , Rani T Usha , Male Sneha
Published: December 2023

Common presenting feature of hepatobiliary and metabolic dysfunction in neonates is cholestatic jaundice. It is essential to recognise the neonatal cholestasis early. Significant proportion of cases of cholestatic disease are constituted by EHBA. If management of Extra Hepatic Biliary Atresia is delayed beyond three months of life, only option available then is liver transplantation.

To analyse etiological factors and to study clinical presentation of cases presenting with cholestasis.

Study the clinical presentation and analyse the etiological factors in infants with cholestasis. To determine the validity of ACS and compare outcomes of EHBA with respect to age at presentation.

Prospective observational study was done in 104 infants with cholestasis who were admitted in Paediatric ward of niloufer hospital from January 2019 to July 2020.

Statistical analysis done by chi square test and fisher’s exact tests.

Of the total 104 cases, 47 cases were diagnosed to be EHBA and 38 cases were found to have neonatal hepatitis.58.6% were male and 41.34%were female and 72 were term and 32 were preterm. Mean age of presentation with EHBA and Neonatal hepatitis was 91 days and 94 days. LFT’s in EHBA cases showed mean TSB 12.19 ± 5 mg/dl Vs 11.7 ± 5.8 mg/dl in NH babies with a p value equal to 0.379. Direct bilirubin revealed 6.44 ± 3.1mg/dl Vs 6.64 ± 3.1mg/dl in NH group (p = 0.824).HIDA scan showed 41% had EHBA, 33.3% had NH

AIIMS Clinical score (ACS) cannot correctly differentiate EHBA from NH.

Survival was significantly higher in infants with EHBA who were operated before 60 days of life.
Intestinal carriage and molecular characteristics of carbapenem resistant Escherichia coli and Klebsiella pneumoniae among patients in intensive care units and outpatients in a tertiary care hospital
Authors: Rangappa Kusuma Gowdra , Rangaiah Ambica
Published: December 2023

Intestinal carriage of carbapenem-resistant and (CREK) plays an important role in the epidemiology of carbapenemase producers. Less is known about the carriage of CREK among the outpatients when compared to carriage among patients in Intensive Care Units. (ICU) Therefore the present study was performed to detect colonization of CREK among ICU patients and outpatients of our tertiary care hospital.

Rectal swabs from ICU patients and stool specimens from outpatients were collected. Identification and antimicrobial susceptibility were performed using Vitek 2 compact system. Screening for CREK was done by two methods and confirmed for carbapenemase production by mCIM. Carbapenemase genes were detected by multiplex polymerase chain reaction.

Overall 460 patients were analyzed for the intestinal carriage of CREK, 230 patients each from ICU and outpatients. 10.4% of outpatients and 26% of ICU patients found positive for CREK carriage. The target genes for carbapenemase production found in 78/86 CREK isolates. The majority of isolates 50/78 (64%) harbored beta-lactamase (bla) NDM gene followed by blaOXA-48 like in 18/78 (23%) isolates and 10/78(12%) isolates had both the genes.

Detection of carbapenem-resistant genes in commensal flora of the gut is worrisome. Building proper awareness about the use of antimicrobials in the community and strict surveillance systems to monitor these resistant bacteria in humans, food-producing animals, and the environment could all help to reduce the colonization of CREK among healthy individuals. Implementation of strict infection control measures and prudent use of carbapenems can help to limit the spread of these superbugs in the hospital.
Follow up of serum ferritin levels in myocardial infarction in Indian males
Authors: Agarwal Shikha , Sablania Praveen
Published: December 2023

National health & nutritional examination survey, 1988-1994, first time reported a significant positive association in iron storage & heart disease risk. Due to the scarcity of this type of study in India, we did this study to find out the relation of serum ferritin with MI

The current study attempts to evaluation association of ferritin levels at the onset of AMI & at 6 day of follow up of subjects.

A total of 39 male patients who were confirmed of having MI on the basis of lipid profile, CKMB, SGOT, SGPT, Trop I, ECG & Chest X Ray were included in the study. Serum ferritin level was estimated in study group on day 1 & day 6 of MI attack while only once in control. Serum ferritin was estimated by enzyme linked fluorescent assay on Mini Vidas auto analyzer from Biomerieux.

Mean serum ferritin levels at Day-1 was not significantly elevated than controls [58.51 (±18.71) ng/ml in day-1 versus 64.09 (±19.42)]. In contrast serum ferritin levels at Day-6 were significantly elevated than controls [226.68 (±18.71) ng/ml at day-6 versus versus ferritin levels in controls (p < 0.001)].

: In conclusion, our data supports that elevated serum ferritin levels are associated with pathogenesis of AMI.
Clinical and hematological evaluation of pancytopenia: A cross-sectional study in a tertiary care center in Western Odisha
Authors: Nayak Sunanda , Sahu Binod Kumar , Mishra Pushpanjali , Tudu Kshetra Mohan
Published: December 2023

Pancytopenia is the outcome of bone marrow abnormalities and progresses with thrombocytopenia, leukopenia, and anemia. The frequently reported clinical manifestations of pancytopenia include infections, hemorrhage, dyspnea, and pallor. This study aimed to improve the diagnostic assessment of pancytopenia by underlying its potential hematological and clinical parameters. 

The enrolled patients underwent hematological and clinical assessments for pancytopenia at Veer Surendra Sai Institute of Medical Science and Research, Odisha, India. The pancytopenia assessment parameters included peripheral blood smear, reticulocyte count, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, mean corpuscular volume, differential count, total platelet count, total leukocyte count, red blood cell count, and hemoglobin level. Patients also underwent bone marrow aspiration and biopsy for diagnostic investigation.

The bone marrow study and peripheral smears were conducted on eighty-eight patients, and findings revealed the incidence of potential pancytopenia causes including, malaria (1%, n=1), multiple myeloma (1%, n=1), metastatic adenocarcinoma (1%, n=1), hemophagocytic lymphohistiocytosis (1%, n=1), tubercular granuloma (1%, n=1), sickle cell crisis (2%, n=2), hypersplenism (3%, n=3), myelodysplastic syndromes (3%, n=3), acute lymphoblastic leukemia (3%, n=3), acute myeloid leukemia (7%, n=6), aplastic anemia (32%, n=28) and megaloblastic anemia (43% n=38). 

Pancytopenia is predominantly caused by megaloblastic anemia and aplastic anemia, respectively. The frequently reported clinical manifestations include bleeding, fever, and weakness. The diagnostic affirmations rely on bone marrow biopsy/aspiration.
Effect of blood glucose & glycated hemoglobin levels on the outcome of patients with acute exacerbation of chronic obstructive pulmonary disease
Authors: Praveen JV , Preethi K , Padmaja B
Published: December 2023

The connection to hyperglycaemia & intense intensifications of persistent obstructive pneumonic infection (COPD) are presently starting to arise. Expanded blood glucose is related with unfriendly clinical results among patients with significant ailments. Hyperglycemia might be related with expanded mortality, length of stay (LOS), & re-confirmations in COPD patients.

This study was finished in 80 hospitalized patients with intense compounding of persistent obstructive aspiratory sickness in the Department of pneumonic medication between June 2021 to January 2022. The segment, clinical data, lab results, radiographic outcomes, & data on Length of stay (LOS), mortality & re-confirmation were gathered. Point of the review is to concentrate on the impact of blood glucose, HbA1c levels on the mean length of medical clinic stay in patients of AECOPD.

Out of 80 COPD individuals, 61(76%) were male & 19(24%) were female. Majority belonged to 56-65 years (38.8%), followed by 66-75 years (28.8%). Of the total 80 COPD individuals, 100% of male patients (n=61) were smokers, 15% of females (n=3) were smokers. Duration of the hospital stay was more with higher RBS values of ≥200mg/dl (9.2 ± 3.5 days) when compared to RBS value of 171-200 mg/dl (7.6±2.3 days) which was more than the RBS group with values of 141-170 (7.2±1.9 days). Whereas for normal RBS values of ≤140 mg/dl mean duration of hospital stay was (5.12±0.82 days).

The conclusion arrived from our study, Higher the RBS at the time of admission, longer the mean duration of stay in the hospital. At admission, RBS more than 170 mg/dl is detrimental in AECOPD patients. High HbA1C levels (>6%) were associated with a high risk of exacerbations.
Role of visual evoked potential (VEP) in indirect traumatic optic nerve (ITON) injuries and assessment of the visual outcome
Authors: P Saravanasankar , Sangeetha D , Sangeetha S
Published: December 2023

To demonstrate the critical function of Visually Evoked Potential (VEP) in the prompt detection of indirect optic neuropathy.

60 patients suspected of having traumatic optic nerve injury underwent VEP testing in < eight hours of traumatic experience.

Baseline visual acuity was revealed to be the most imperative prognosticator of eventual visual outcome. The VEP was instrumental in the primary detection as well as validation of ITON. Additionally, VEP aided in predicting prognosis and follow-up for patients with IITON. Visual recovery is impossible in the absence of recordable VEP waves. The manifestation of orbital fractures wasn't associated with a preliminary or ultimate visual perception decrease. Patients who present < 8 hours following ITON with normal initial visual acuity, VEP alterations, and lower RAPD grades may have a greater chance of recovering final visual perception when treated with an instantaneous high steroid dosage.

The above-mentioned prognostic markers in patients with ITON may be beneficial in predicting visual prognosis and determining the need for surgical therapy in patients who experience vision loss following head trauma.
Hepatitis –A late manifestation of COVID-19 in pediatric population?
Authors: Agrawal Roopa , Agarwal Gaurav , Sahu Rupesh , Jain Ashish , Asati Deepesh , Rawat Sumit
Published: December 2023

Complete spectrum of covid 19 infection in children as well as its sequaele is still unknown to the world even after two years of ongoing pandemic. Many manifestations of covid 19 have been missed and are yet to be identified. In this study, we aim to hypothesize hepatitis as a probable late manifestation of COVID-19 infection in children.

It was a descriptive retrospective study, in which we have included twenty patients who presented with hepatitis in the pediatric department of a secondary level care centre in Sagar from May to July 2021. And we investigated them further to find out the cause of Hepatitis.

Among the 20 patients with HEPATITIS, 15 were tested for covid antibody levels, out of them 14 had raised level of SARS-CoV-2 antibody titre.

Pediatricians should recognize that the clinical spectrum of COVID-19 in children can be wider than previously described, often with hepatitis as late manifestation of COVID-19 in children, apart from MIS-C.
Evaluation of serum ischemia modified albumin (IMA) level and serum uric acid level as a preliminary biomarker of epilepsy
Authors: Jain Ankit , Ahirwar Ashok Kumar , Jain Rashmi , Asia Priyanka , Sharma Anuj
Published: December 2023

Oxidative stress, hypoxia, and ischemia are considered prime factors in the pathogenesis of epilepsy. Hyperuricemia (HU) is a common incidental finding in epileptic patients, but the importance of HU as a risk factor in epilepsy is debated. Many hypothetical mechanisms that link HU to increased oxidative stress in epilepsy have been put forward. This research aimed to evaluate the role of serum Ischemia Modified Albumin (IMA) level and serum uric acid (UA) level as a preliminary biomarker in the diagnosis of epilepsy.

: The present cross-sectional research was conducted on 25 individuals having epilepsy and 25 healthy individuals. Serum uric acid level had estimated by the uricase method. Serum IMA was evaluated by albumin cobalt binding assay to assess oxidative stress, hypoxia, and ischemia. 

 Mean Serum UA and IMA level were found significantly high (p<0.001) in epileptic group. In the epileptic group, 76 % (19/25) individuals had HU. Mean serum IMA was higher in epileptic individuals with HU compared to epileptic individuals with normal serum UA levels. Correlation between serum UA level and serum IMA level was found positive among the study population. Serum UA showed a significant odd ratio to predict epilepsy on binary logistic analysis.

: The present study revealed that serum UA levels and IMA levels escalated in epileptic patients. Thus, serum UA levels and IMA levels can be deemed as preliminary biomarkers for the diagnosis of epilepsy.
Utility of laparoscopic hysterectomy compared to vaginal and abdominal hysterectomy for benign gynecological conditions
Authors: Jaiswal Sarita , K Ramana
Published: December 2023

In spite of availability of procedures which are less invasive for hysterectomy, some prefer abdominal approach for the hysterectomy (TAH). Laparoscopic hysterectomy (TLH) is useful for the patients, as they recover fast and the convalescence period is reduced.

To compare and evaluate three different methods of hysterectomy for benign gynecological disorders with regard to time for recovery, outcome after surgery, cost-effectiveness and complications due to surgery.

Prospective study conducted on 90 patients who underwent hysterectomy for benign gynecological conditions. Patients were assigned to either TAH (n=30), TLH (n=30) or Vaginal hysterectomy (VH) (n=30), with or without salpingo-oophorectomy. All patients presenting in the gynecology OPD with indications for hysterectomy with or without salpingo-oophorectomy were included. Pre-operative parameters like age, basal metabolic index, intra-operative and post-operative parameters like reduction in hemoglobin etc. were compared in three groups.

The mean blood loss, Time from surgery to tolerance of normal diet (days), Time from surgery to unassisted ambulation (days), post-operative pain score on day 3, mean reduction in hemoglobin and duration of hospital stay (days) were significantly (p<0.05) higher in patients who underwent total abdominal hysterectomy compared to total laparoscopic or vaginal hysterectomy. In terms of intra-operative and post-operative complications, operative time, hospital bill and satisfaction score the differences were not significant statistically (p>0.05).

Total laparoscopic hysterectomy and vaginal hysterectomy are safe and less invasive alternative, compared to abdominal hysterectomy, and show significantly better post-operative reconstitution
Interventional knowledge, attitude and practice study of standard precautions among health care workers at a tertiary care hospital in Western India
Authors: Mehta Tanmay K , Shah Dharati T , Pethani Jayshri D
Published: December 2023

Standard precautions are the backbone of any efficient infection control program. Compliance with standard precautions has been a major challenge for health care workers, especially in developing countries.

To access the impact of the training program on health care workers (HCW) knowledge, attitude, and practice towards standard precautions.

We conducted an interventional Knowledge, Attitude, and Practice (KAP) study among 150 HCW (50 Doctors, 50 Nurses, and 50 Technicians) in a tertiary care hospital from June 2019 to December 2019. We carried out educational interventions through training sessions with pre- and post-test questionnaires. We compared pre and post questionnaire mean scores to access the impact of short educational videos and seminars on HCWs using unpaired t-tests.

HCWs have poor KAP on important aspects of standard precautions. Pre-intervention KAP mean scores were highest among doctors, followed by lab technicians and nurses. After training intervention, improvement in knowledge, attitude, and practice among all 3 types of HCWs were statistically significant (P-value <0.005, unpaired t-test).

Low pre-intervention knowledge and attitude practice scores regarding standard precautions among doctors, nurses, and lab technicians were improved after training significantly. Hence, we recommend training programs regarding standard precautions should be regularly conducted in health-care facilities to promote good infection control practices and mitigate the risk of hospital-acquired infection. This has future implications in terms of reduced morbidity and mortality in resource limited settings.
Prediction of culprit artery from ECG in acute ST elevation myocardial infarction and correlating with coronary angiography
Authors: Madhavi K.V. Phani , Padmalatha P , Nag P Suhrut
Published: December 2023

Acute myocardial infarction (AMI) is one of the most common diagnoses in hospitalized patients in industrialized countries. The early (30-day) mortality rate from AMI is ~30%, with more than half of these deaths occurring before the stricken individual reaches the hospital.When patients present with acute coronary syndrome, The 12-lead electrocardiogram (ECG) recorded by the alarmed general practitioner or ambulance staff is a pivotal diagnostic and triage tool since it is at the center of the decision pathway for management. In this study the accuracy of ECG in identifying the culprit artery was determined by comparing ECG finding with angiography finding which is a direct visualization procedure.

To assess the value of electrocardiogram in predicting the culprit artery in acute ST elevation MI and correlating with coronary angiogram finding.

A Cross Sectional Observational study was carried out for a period of 11months from February 2021 to December 2021 among 100 Patients admitted to ICCU, Dept of Cardiology, King George Hospital, Visakhapatnam who were diagnosed with acute ST-elevation myocardial infarction. The accuracy of ECG in identifying the culprit artery was determined by comparing ECG finding with angiography finding which is a direct visualization procedure.

The sensitivity of ECG in predicting LAD as infarct related artery when compared to CAG, which was taken as standard test is 94.10%, specificity 89.79% the positive predictive value is 90.56% and the negative predictive value is 93.61%.

In the present study, ECG well correlated with CAG (90.56%) in predicting LAD as infarct related artery.