bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimation of fetal weight by ultrasonography after preterm premature rupture of membranes: comparison of different formulas
Authors: Esin Sertac , Hayran Mutlu , Tohma Yusuf Aytac , Guden Mahmut , Alay Ismail , Esinler Deniz , Yalvac Serdar , Kandemir Omer
Published: December 2016

Objective:

To compare different ultrasonographic fetal weight estimation formulas in predicting the fetal birth weight of preterm premature rupture of membrane (PPROM) fetuses.

Methods:

Based on the ultrasonographic measurements, the estimated fetal weight (EFW) was calculated according to the published formulas. The comparisons used estimated birth weight (EBW) and observed birth weight (OBW) to calculate the mean absolute percentage error [(EBW–OBW)/OBW×100], mean percentage error [(EBW–OBW)/OBW×100)] and their 95% confidence intervals.

Results:

There were 234 PPROM patients in the study period. The mean gestational age at which PPROM occured was 31.2±3.7 weeks and the mean gestational age of delivery was 32.4±3.2 weeks. The mean birth weight was 1892±610 g. The median absolute percentage error for 33 formulas was 11.7%. 87.9% and 21.2% of the formulas yielded inaccurate results when the cut-off values for median absolute percentage error were 10% and 15%, respectively. The Vintzileos’ formula was the only method which had less than or equal to 10% absolute percentage error in all age and weight groups.

Conclusions:

For PPROM patients, most of the formulas designed for sonographic fetal weight estimation had acceptable performance. The Vintzileos’ method was the only formula having less than 10% absolute percentage error in all gestational age and weight groups; therefore, it may be the preferred method in this cohort. Amniotic fluid index (AFI) before delivery had no impact on the performance of the formulas in terms of mean percentage errors.
Crystal structure of trimethylammonium 4-((4-carboxyphenyl)sulfonyl)benzoate, C17H19NO6S
Authors: Hou Shanshan , Hou Yimin , Wu Mingxia
Published: December 2016

C17H19NO6S, monoclinic, C2/c (no. 15), a = 20.868(3) Å, b = 11.6189(15) Å, c = 15.0133(19) Å, β = 101.344(7)°, V = 3569.1(8) Å3, Z = 8, R
gt(F) = 0.0510, wR
ref(F
2) = 0.1714, T = 296(2) K.
Crystal structure of (E)-5-((4-chlorophenyl)diazenyl)-2-(5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)-4-methylthiazole, C23H17ClFN5S2
Authors: El-Hiti Gamal A. , Abdel-Wahab Bakr F. , Baashen Mohammed , Hegazy Amany S. , Kariuki Benson M.
Published: December 2016

C23H17ClFN5S2, monoclinic, P21/c (no. 14), a = 20.9691(12) Å, b = 11.5316(6) Å, c = 9.2546(4) Å, β = 95.484(4)°, V = 2227.6(2) Å3, Z = 4, R
gt(F) = 0.0468, wR
ref(F
2) = 0.1126, T = 296 K.
Development of partial miscibility in polycarbonate/polypropylene blends via annealing
Authors: Samsudin Sani A. , Kelly Catherine A. , Kukureka Stephen N. , Jenkins Mike J.
Published: December 2016

The morphology, dynamic mechanical properties and infrared spectra of polycarbonate (PC)/polypropylene (PP) blends were investigated. As expected, PC and PP were immiscible when blended together; however partial miscibility developed following annealing. The miscibility of one polymer in the other was examined using the modified Fox equation and the values of the Flory-Huggins polymer-polymer interaction parameter (χ
12) were also calculated following the Kim and Burns approach. Moreover, the possible causes for partial miscibility in the annealed PC/PP blends were explored by infrared spectroscopy. It was concluded that annealing caused degradation of PP, leading to the formation of polar groups which were then able to interact with PC generating regions of partial miscibility.
Der Einfluss von Religiosität auf die Bereitschaft, Psychotherapie in Anspruch zu nehmen
Authors: Stephan Valeska , Utsch Michael
Published: December 2016

Therapiestudien über den Umgang mit religiösen Bedürfnissen von amerikanischen Patientinnen und Patienten zeigen, dass hochreligiöse Menschen meist negative Erwartungen zum Umgang mit Religiosität innerhalb der Psychotherapie aufweisen. Zudem stellte sich heraus, dass hochreligiöse Menschen weniger bereit sind, eine Psychotherapie in Anspruch zu nehmen als weniger religiöse Menschen. Die vorliegende Pilotstudie untersucht, ob auch in Deutschland hochreligiöse (christliche und muslimische) Menschen eine geringere Nutzungsbereitschaft für Psychotherapie aufweisen als weniger religiöse oder nichtreligiöse Menschen. Zudem wurde überprüft, inwiefern die Erwartungen zum Umgang mit Religiosität in der Psychotherapie Gründe für diesen möglichen Zusammenhang darstellen. An der Online-Befragung nahmen 1002 Studierende aus ganz Deutschland teil. Die bisherigen Befunde aus den USA wurden dabei bestätigt: Hochreligiöse Personen zeigten eine geringere Nutzungsbereitschaft für Psychotherapie als weniger religiöse und nichtreligiöse Personen. Dieser Zusammenhang wurde durch die Erwartungen zum Umgang mit Religiosität in der Psychotherapie teilweise mediiert. Praktische Implikationen dieses Befundes werden diskutiert.
Re-determining the cut-off points of FIB-4 for patients monoinfected with chronic hepatitis B virus infection
Authors: Kayadibi Huseyin , Yasar Bulent , Ozkara Selvinaz , Demirpek Ugur , Uyanik Metin , Sertoglu Erdim , Ozcelik Fatih , Gonen Can , Aksaray Sebahat
Published: December 2016

Objective

This study aimed to determine significant liver fibrosis and cirrhosis with different FIB-4 cut-off points, and the need for liver biopsy (LB) by optimizing the initially established cut-off points of 1.45 and 3.25.

Materials and methods

The study included 201 patients monoinfected with chronic HBV. METAVIR classification was used to determine the stage of fibrosis. ROC analysis and the Youden index were performed to define the optimum cut-off points.

Results

A FIB-4 cut-off point of 1.45 and 1.62 generated Youden indexes of 0.51 and 0.55, the accuracy of 78.6% and 81.1% for significant liver fibrosis, respectively. The FIB-4 cut-off was set at 2.40 and 3.25 Youden indexes were 0.46 and 0.16, accuracies were 79.6% and 69.7% for significant liver fibrosis, respectively. A cut-off point of 1.45 and 1.62 for FIB-4 generated Youden indexes of 0.62 and 0.66, the accuracies of 81.6% and 84.1% for cirrhosis, while the FIB-4 cut-off point of 2.40 and 3.25 generated Youden indexes of 0.59 and 0.22, with the accuracies of 90% and 84.1% for cirrhosis, respectively.

Conclusions

The FIB-4 cut-off points of 1.62 and 2.40 have higher accuracy and may decrease the need for LB 12% more than the initially established ones in HBV monoinfected patients.
Effect of Amorphisation on the Thermal Properties of Nanostructured Membranes
Authors: Termentzidis Konstantinos , Verdier Maxime , Lacroix David
Published: December 2016

The majority of the silicon devices contain amorphous phase and amorphous/crystalline interfaces which both considerably affect the transport of energy carriers as phonons and electrons. In this article, we investigate the impact of amorphous phases (both amorphous silicon and amorphous SiO2) of silicon nanoporous membranes on their thermal properties via molecular dynamics simulations. We show that a small fraction of amorphous phase reduces dramatically the thermal transport. One can even create nanostructured materials with subamorphous thermal conductivity, while keeping an important crystalline fraction. In general, the a-SiO2 shell around the pores reduces the thermal conductivity by a factor of five to ten compared to a-Si shell. The phonon density of states for several systems is also given to give the impact of the amorphisation on the phonon modes.
Analytic Approximations to Nonlinear Boundary Value Problems Modeling Beam-Type Nano-Electromechanical Systems
Authors: Zou Li , Liang Songxin , Li Yawei , Jeffrey David J.
Published: December 2016

Nonlinear boundary value problems arise frequently in physical and mechanical sciences. An effective analytic approach with two parameters is first proposed for solving nonlinear boundary value problems. It is demonstrated that solutions given by the two-parameter method are more accurate than solutions given by the Adomian decomposition method (ADM). It is further demonstrated that solutions given by the ADM can also be recovered from the solutions given by the two-parameter method. The effectiveness of this method is demonstrated by solving some nonlinear boundary value problems modeling beam-type nano-electromechanical systems.
Reproducibility of the Internal Load and Performance-Based Responses to Simulated Amateur Boxing
Authors: Thomson Edward D. , Lamb Kevin L.
Published: December 2016

Thomson, ED and Lamb, KL. Reproducibility of the internal load and performance-based responses to simulated amateur boxing. J Strength Cond Res 31(12): 3396–3402, 2017—The aim of this study was to examine the reproducibility of the internal load and performance-based responses to repeated bouts of a three-round amateur boxing simulation protocol (boxing conditioning and fitness test [BOXFIT]). Twenty-eight amateur boxers completed 2 familiarization trials before performing 2 complete trials of the BOXFIT, separated by 4–7 days. To characterize the internal load, mean (HRmean) and peak (HRpeak) heart rate, breath-by-breath oxygen uptake (V̇o
2), aerobic energy expenditure, excess carbon dioxide production (CO2excess), and ratings of perceived exertion were recorded throughout each round, and blood lactate determined post-BOXFIT. Additionally, an indication of the performance-based demands of the BOXFIT was provided by a measure of acceleration of the punches thrown in each round. Analyses revealed there were no significant differences (p > 0.05) between repeated trials in any round for all dependent measures. The typical error (coefficient variation %) for all but 1 marker of internal load (CO2excess) was 1.2–16.5% and reflected a consistency that was sufficient for the detection of moderate changes in variables owing to an intervention. The reproducibility of the punch accelerations was high (coefficient of variance % range = 2.1–2.7%). In general, these findings suggest that the internal load and performance-based efforts recorded during the BOXFIT are reproducible and, thereby, offer practitioners a method by which meaningful changes impacting on performance could be identified.
Feature Writer 2013: Alice Garner
Authors: Team Offset Editorial
Published: December 2016

Alice Garner is a historian, musician, actor and writer. She haspublished two books, The Student Chronicles (MUP, 2006),a memoir of her undergraduate experience, and A Shifting Shore:Locals, Outsiders and the Transformation of a French Fishing Town,1823-2000 (Cornell University Press, 2005), which was shortlisted forthe NSW Premier’s General History Prize.
Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four TransgenicX. laevisModels of Retinitis Pigmentosa
Authors: Vent-Schmidt Ruanne Y.J. , Wen Runxia H. , Zong Zusheng , Chiu Colette N. , Tam Beatrice M. , May Christopher G. , Moritz Orson L.
Published: December 2016

Retinitis pigmentosa (RP) is an inherited retinal degeneration (RD) that leads to blindness for which no treatment is available. RP is frequently caused by mutations inRhodopsin; in some animal models, RD is exacerbated by light. Valproic acid (VPA) is a proposed treatment for RP and other neurodegenerative disorders, with a phase II trial for RP under way. However, the therapeutic mechanism is unclear, with minimal research supporting its use in RP. We investigated the effects of VPA onXenopus laevismodels of RP expressing human P23H, T17M, T4K, and Q344ter rhodopsins, which are associated with RP in humans. VPA ameliorated RD associated with P23H rhodopsin and promoted clearing of mutant rhodopsin from photoreceptors. The effect was equal to that of dark rearing, with no additive effect observed. Rescue of visual function was confirmed by electroretinography. In contrast, VPA exacerbated RD caused by T17M rhodopsin in light, but had no effect in darkness. Effects in T4K and Q344ter rhodopsin models were also negative. These effects of VPA were paralleled by treatment with three additional histone deacetylase (HDAC) inhibitors, but not other antipsychotics, chemical chaperones, or VPA structural analogues. In WT retinas, VPA treatment increased histone H3 acetylation. In addition, electron microscopy showed increased autophagosomes in rod inner segments with HDAC inhibitor (HDACi) treatment, potentially linking the therapeutic effects in P23H rhodopsin animals and negative effects in other models with autophagy. Our results suggest that the success or failure of VPA treatment is dependent on genotype and that HDACi treatment is contraindicated for some RP cases.

SIGNIFICANCE STATEMENTRetinitis pigmentosa (RP) is an inherited, degenerative retinal disease that leads to blindness for which no therapy is available. We determined that valproic acid (VPA), currently undergoing a phase II trial for RP, has both beneficial and detrimental effects in animal models of RP depending on the underlying disease mechanism and that both effects are due to histone deacetylase (HDAC) inhibition possibly linked to autophagy regulation. Off-label use of VPA and other HDAC inhibitors for the treatment of RP should be limited to the research setting until this effect is understood and can be predicted. Our study suggests that, unless genotype is accounted for, clinical trials for RP treatments may give negative results due to multiple disease mechanisms with differential responses to therapeutic interventions.
Target-Dependent Compartmentalization of the Corelease of Glutamate and GABA from the Mossy Fibers
Authors: Galván Emilio J. , Gutiérrez Rafael
Published: December 2016

The mossy fibers (MFs) corelease glutamate and GABA onto pyramidal cells of CA3 during development, until the end of the third postnatal week. However, the major target cells of the MF are the interneurons of CA3. Therefore, it has been shown that the interneurons of the hilus and stratum lucidum receive this dual monosynaptic input on MF stimulation. Because the plasticity of glutamatergic transmission from the different terminals of the MF is target specific, we here asked whether the corelease of glutamate and GABA was also subjected to a target-dependent compartmentalization. We analyzed the occurrence and plasticity of MF simultaneous glutamatergic–GABAergic signaling onto interneurons of the different strata of CA3 in rats during the third postnatal week. We show the coexistence of time-locked, glutamate receptor and GABA receptor-mediated mono synaptic responses evoked by MF stimulation in interneurons from stratum lucidum and stratum radiatum, but not in interneurons from stratum lacunosum-moleculare. As expected from the transmission of MF origin, MF GABAergic responses were depressed by the activation of metabotropic glutamate receptors. Strikingly, while MF glutamatergic responses underwent LTD, the simultaneous MF GABAergic responses of stratum lucidum interneurons, but not of stratum radiatum interneurons, displayed a Hebbian form of LTP that was mimicked by PKC activation. PKA activation potentiated MF glutamatergic responses of stratum radiatum interneurons, whereas in stratum lucidum interneurons only GABAergic responses were potentiated. We here disclose that the corelease of glutamate and GABA, as well as their plasticity are compartmentalized in a target-dependent manner, showing counterbalanced compensatory plasticity of two neurotransmitters released by different terminals of the same pathway.

SIGNIFICANCE STATEMENTThe mossy fibers transiently corelease glutamate and GABA onto pyramidal cells of CA3. We here describe that they can also corelease these amino acids onto interneurons, in a target-dependent manner. Many interneurons in stratum lucidum and stratum radiatum receive both signals, while those in stratum lacunosum-moleculare exclusively receive a glutamatergic signal. It is noteworthy that glutamatergic LTD, which is known to exist on stratum lucidum interneurons, coexists in the same pathway with a presynaptic form of GABAergic LTP, while interneurons of stratum radiatum, despite receiving this dual signaling, do not display such plasticity. The GABAergic LTP is mimicked with PKA or PKC activation. We disclose compartmentalized corelease of glutamate and GABA and its differential plasticity from a single pathway onto different interneuron sets.
Promoted Interaction of C/EBPα with DemethylatedCxcr3Gene Promoter Contributes to Neuropathic Pain in Mice
Authors: Jiang Bao-Chun , He Li-Na , Wu Xiao-Bo , Shi Hui , Zhang Wen-Wen , Zhang Zhi-Jun , Cao De-Li , Li Chun-Hua , Gu Jun , Gao Yong-Jing
Published: December 2016

DNA methylation has been implicated in the pathogenesis of chronic pain. However, the specific genes regulated by DNA methylation under neuropathic pain condition remain largely unknown. Here we investigated how chemokine receptor CXCR3 is regulated by DNA methylation and how it contributes to neuropathic pain induced by spinal nerve ligation (SNL) in mice. SNL increasedCxcr3mRNA and protein expression in the neurons of the spinal cord. Meanwhile, the CpG (5′-cytosine-phosphate-guanine-3′) island in theCxcr3gene promoter region was demethylated, and the expression of DNA methyltransferase 3b (DNMT3b) was decreased. SNL also increased the binding of CCAAT (cytidine–cytidine–adenosine–adenosine–thymidine)/enhancer binding protein α (C/EBPα) withCxcr3promoter and decreased the binding of DNMT3b withCxcr3promoter in the spinal cord. C/EBPα expression was increased in spinal neurons after SNL, and inhibition of C/EBPα by intrathecal small interfering RNA attenuated SNL-induced pain hypersensitivity and reducedCxcr3expression. Furthermore, SNL-induced mechanical allodynia and heat hyperalgesia were markedly reduced inCxcr3−/−mice. Spinal inhibition ofCxcr3by shRNA or CXCR3 antagonist also attenuated established neuropathic pain. Moreover, CXCL10, the ligand of CXCR3, was increased in spinal neurons and astrocytes after SNL. Superfusing spinal cord slices with CXCL10 enhanced spontaneous EPSCs and potentiated NMDA-induced and AMPA-induced currents of lamina II neurons. Finally, intrathecal injection of CXCL10 induced CXCR3-dependent pain hypersensitivity in naive mice. Collectively, our results demonstrated that CXCR3, increased by DNA demethylation and the enhanced interaction with C/EBPα, can be activated by CXCL10 to facilitate excitatory synaptic transmission and contribute to the maintenance of neuropathic pain.

SIGNIFICANCE STATEMENTPeripheral nerve injury induces changes of gene expression in the spinal cord that may contribute to the pathogenesis of neuropathic pain. CXCR3 is a chemokine receptor. Whether it is involved in neuropathic pain and how it is regulated after nerve injury remain largely unknown. Our study demonstrates that spinal nerve ligation downregulates the expression of DNMT3b, which may cause demethylation ofCxcr3gene promoter and facilitate the binding of CCAAT/enhancer binding protein α withCxcr3promoter and further increase CXCR3 expression in spinal neurons. The upregulated CXCR3 may contribute to neuropathic pain by facilitating central sensitization. Our study reveals an epigenetic mechanism underlying CXCR3 expression and also suggests that targeting the expression or activation of CXCR3 signaling may offer new therapeutics for neuropathic pain.
Selective Deletion of Sodium Salt Taste during Development Leads to Expanded Terminal Fields of Gustatory Nerves in the Adult Mouse Nucleus of the Solitary Tract
Authors: Sun Chengsan , Hummler Edith , Hill David L.
Published: December 2016

Neuronal activity plays a key role in the development of sensory circuits in the mammalian brain. In the gustatory system, experimental manipulations now exist, through genetic manipulations of specific taste transduction processes, to examine how specific taste qualities (i.e., basic tastes) impact the functional and structural development of gustatory circuits. Here, we used a mouse knock-out model in which the transduction component used to discriminate sodium salts from other taste stimuli was deleted in taste bud cells throughout development. We used this model to test the hypothesis that the lack of activity elicited by sodium salt taste impacts the terminal field organization of nerves that carry taste information from taste buds to the nucleus of the solitary tract (NST) in the medulla. The glossopharyngeal, chorda tympani, and greater superficial petrosal nerves were labeled to examine their terminal fields in adult control mice and in adult mice in which the α-subunit of the epithelial sodium channel was conditionally deleted in taste buds (αENaC knockout). The terminal fields of all three nerves in the NST were up to 2.7 times greater in αENaC knock-out mice compared with the respective field volumes in control mice. The shapes of the fields were similar between the two groups; however, the density and spread of labels were greater in αENaC knock-out mice. Overall, our results show that disruption of the afferent taste signal to sodium salts disrupts the normal age-dependent “pruning” of all terminal fields, which could lead to alterations in sensory coding and taste-related behaviors.

SIGNIFICANCE STATEMENTNeural activity plays a major role in the development of sensory circuits in the mammalian brain. To date, there has been no direct test of whether taste-elicited neural activity has a role in shaping central gustatory circuits. However, recently developed genetic tools now allow an assessment of how specific taste stimuli, in this case sodium salt taste, play a role in the maturation of the terminal fields in the mouse brainstem. We found that the specific deletion of sodium salt taste during development produced terminal fields in adults that were dramatically larger than in control mice, demonstrating for the first time that sodium salt taste-elicited activity is necessary for the normal maturation of gustatory inputs into the brain.
Independent Neural Computation of Value from Other People's Confidence
Authors: Campbell-Meiklejohn Daniel , Simonsen Arndis , Frith Chris D. , Daw Nathaniel D.
Published: December 2016

Expectation of reward can be shaped by the observation of actions and expressions of other people in one's environment. A person's apparent confidence in the likely reward of an action, for instance, makes qualities of their evidence, not observed directly, socially accessible. This strategy is computationally distinguished from associative learning methods that rely on direct observation, by its use of inference from indirect evidence. In twenty-three healthy human subjects, we isolated effects of first-hand experience, other people's choices, and the mediating effect of their confidence, on decision-making and neural correlates of value within ventromedial prefrontal cortex (vmPFC). Value derived from first-hand experience and other people's choices (regardless of confidence) were indiscriminately represented across vmPFC. However, value computed from agent choices weighted by their associated confidence was represented with specificity for ventromedial area 10. This pattern corresponds to shifts of connectivity and overlapping cognitive processes along a posterior-anterior vmPFC axis. Task behavior and self-reported self-reliance for decision-making in other social contexts correlated. The tendency to conform in other social contexts corresponded to increased activation in cortical regions previously shown to respond to social conflict in proportion to subsequent conformity (Campbell-Meiklejohn et al., 2010). The tendency to self-monitor predicted a selectively enhanced response to accordance with others in the right temporoparietal junction (rTPJ). The findings anatomically decompose vmPFC value representations according to computational requirements and provide biological insight into the social transmission of preference and reassurance gained from the confidence of others.

SIGNIFICANCE STATEMENTDecades of research have provided evidence that the ventromedial prefrontal cortex (vmPFC) signals the satisfaction we expect from imminent actions. However, we have a surprisingly modest understanding of the organization of value across this substantial and varied region. This study finds that using cues of the reliability of other peoples' knowledge to enhance expectation of personal success generates value correlates that are anatomically distinct from those concurrently computed from direct, personal experience. This suggests that representation of decision values in vmPFC is suborganized according to the underlying computation, consistent with what we know about the anatomical heterogeneity of the region. These results also provide insight into the observational learning process by which someone else's confidence can sway and reassure our choices.
Capturing native interactions: intrinsic methods to study chromatin conformation
Authors: Rowley M Jordan , Corces Victor G
Published: December 2016

The 3D organization of chromatin controls gene expression through spatial interactions between genomic loci. FISH and 3C‐based methods that are commonly used to study chromatin organization utilize chemical crosslinking, a step that may introduce biases in detectable chromatin interactions. In their recent study, Papantonis and colleagues (Brant et al, ) developed alternative new methods of detecting chromatin contacts without the use of chemical crosslinking agents. These tools increase the resolution and confidence at which interactions can be identified, and may be informative for chromatin interaction dynamics.
Increased prevalence of obstructive sleep apnea in patients with Cushing’s syndrome compared with weight- and age-matched controls
Authors: Gokosmanoğlu Feyzi , Güzel Aygül , Kan Elif Kilic , Atmaca Hulusi
Published: December 2016

Objective

Diabetes mellitus and obesity are well-known risk factors associated with obstructive sleep apnea (OSA). Cushing’s syndrome (CS) is also characterized by obesity and diabetes mellitus. However, the association between CS and OSA remains unclear. Therefore, we investigated the possible associations between CS and OSA in this study.

Patients and methods

Thirty female patients with newly diagnosed active CS and 30 age-, gender- and body mass index (BMI)-matched controls were included in this study. All participants were evaluated by overnight polysomnography. OSA was defined as having an apnea–hypopnea index (AHI) score of ≥5 events/h. Insulin resistance was calculated by homeostasis model assessment (HOMA) scores. Fasting serum cortisol was also determined.

Results

The prevalence of OSA was higher (50% vs 23%,P = 0.003) in patients with CS compared with the control subjects. The mean HOMA (P = 0.046) and AHI (P = 0.028) scores were higher in patients with CS compared with the control subjects. AHI was positively correlated with the HOMA scores (r = 0.281,P = 0.046) in both groups. Linear regression analysis showed that serum cortisol remained as an independent predictor for AHI after controlling for BMI and HOMA score (P < 0.001).

Conclusions

The prevalence of OSA increased in patients with CS compared with control subjects with similar ages and BMI levels. Hypercortisolemia is an independent risk factor for developing OSA. The presence of OSA needs to be considered in patients with CS.
Burnout as a Selected Aspect Affecting the Work Performance of a Social Worker
Authors: Lachytová Lenka , Kalanin Peter
Published: December 2016

The aim of the empirical study is to identify the symptoms and the preventive measuresof social workers' burnout, according to correlations of age, level of education, professionalexperience, length and the site of occupation.Design study. The study was carried out (from February to May 2016) on 49 respondents, socialworkers, by deliberate choice of typology: former colleagues currently working in NGOs of Košiceand Prešov regions, with who we had participated in various projects providing general-utilityservices. The Inventory of Burnout Symptom by T. and J. Tošner was used for processing thecollected data. The completion of this study is the correct implementation of innovative advancedtechnologies forming a part of the culture of the organization with clearly named functions andduties of the individual members of the working team
The Quality of Seniors' Life in Their Natural Environment
Authors: Lachytová Lenka , Kalanin Peter
Published: December 2016

The aim of the research study is to investigate the quality of life of seniors at home andtheir satisfaction in the domains of physical health, survival, social relations and the environmentitself.Design studio. We conducted the study on a sample of 80 respondents / seniors living at home inVranov nad Topľou. For processing the obtained data, we used the following statistical methods -the Fisher's F-test and Student's t-test. For detecting the data from respondents we chose ananonymous standardized questionnaire WHOQOL-BREF (World Health Organization Quality ofLife - BREF), which is a shortened version of the WHOQOL-100. As completion of this study is theimplementation of mechanisms supporting the quality of life of seniors in a natural environmentwith an emphasis on preventive measures of social policy to maintain a reasonable quality of life
Studi Literatur tentang Riset Zakat
Authors: Rusydiana Aam Slamet , Al Farisi Salman
Published: December 2016

Literature Study on Zakah Research. Zakah is not only as religious rituality but also could touch humanity aspect by empowering its potency to maximize public wealth. The research related to zakah is still lacking compare to Islamic banking research. This study review on research around zakah. The study use descriptive statistical analysis based on 100 journal publications related to zakah, both national and international journal. The entire sample journal publications have published last 5 years from 2011 to 2015. Results show that the zakah research is still dominated by the discussion of zakah institution (26%), followed by distribution of zakah(22%), zakah management (21%) and poverty (20%). The last theme is about zakah collection (11%). In addition, comparison of quantitative research and mixed methods are still far less than the qualitative approach.DOI: 10.15408/ajis.v16i2.4458
Redes sociais e a promoção de diálogo entre israelenses e palestinos
Authors: Barkay Rafaela
Published: December 2016

O presente estudo trata da interação online entre israelenses e palestinos observada em um grupo de discussão no Facebook durante os anos de 2014/2015. Ao explorar o potencial de diálogo entre indivíduos separados fisicamente promovido pelo advento das redes sociais, e buscar fundamentação em modelos desenvolvidos na área de Resolução de Conflitos, pretende-se demostrar a possibilidade de encontro entre estas duas populações em conflito, mesmo que as barreiras físicas e as políticas de Estado o impeçam de ser presencial.
The insoluble conflict of the racial divide – white and black – in Nella Larsen’s novels Passing and Quicksand
Authors: Müller Luciane Oliveira
Published: December 2016

Este trabalho apresenta uma leitura dos romances Quicksand e Passing na sala de aula focando nas questões de raça e conflitos de passing. Esses romances foram publicados, respectivamente em 1928 e 1929, pela escritora Afro- mericana Nella Larsen durante o movimento cultural e estético chamado Harlem Renaissance, um movimento cujo apogeu aconteceu nos anos 20 do século passado provocando a elevação da consciência racial e a emergência da literatura Afro-americana. Nesta década, a experiência de passing constituía um dos temas privilegiados em alguns romances de escritores Afro-americanos. Minha análise se sustenta na obra de Thadious M. Davis, Elaine K. Ginsber e Martha J. Cutter em relação a conflitos raciais e identitários. No entrelaçamento de elementos psicológicos e culturais, minha leitura mostra como esses romances dramatizam o conflito insolúvel da raça dividida – branca e negra – que destaca as lutas e dificuldades das personagens quando se deparam com o vazio do pertencimento do qual trata a experiência de passing. Esta pesquisa tem como objetivo abordar e discutir em sala de aula o aspecto cultural de conflitos raciais que é algo sempre atual e relevante.
Amphibia, Anura, Hylidae Rafinesque, 1815 and Hylodidae Günther, 1858: distribution extension and new records for Santa Catarina, southern Brazil
Authors: Lucas Elaine M. , Garcia Paulo C. A.
Published: December 2016

In the present study we report new records of the anurans Hypsiboas curupi, Scinax littoralis, Dendropsophus elegans, and Crossodactylus schmidti for the state of Santa Catarina. These records expand the geographic distribution currently known for these species and contribute for the knowledge of the southern Brazilian anuran fauna.
Pisces, Gymnotiformes, Hypopomidae, Brachyhypopomus gauderio Giora and Malabarba, 2009: new species record at Taim Ecological Reserve, south Brazil
Authors: Correa Fabiano , Garcia Alexandre Miranda , Bemvenuti Marlise De Azevedo , Vieira João Paes
Published: December 2016

The present paper describes a new occurrence of the species Brachyhypopomus gauderio Giora and Malabarba, 2009 in the Taim Ecological Reserve, Rio Grande do Sul state, Brazil.
Charophyceae, Charales, Characeae, Chara drouetii R.D. Wood, 1965: first record from the state of Quintana Roo, Mexico
Authors: Alix Mitchell S. , Scribailo Robin W.
Published: December 2016

Chara drouetii R.D. Wood, 1965 was recently collected during floristic surveys of aquatic macrophytes in the Yucatán Peninsula, Mexico. This discovery represents the first documented record for this species from the state of Quintana Roo, Mexico. This report extends the range of Chara drouetii by approximately 300 km east of the nearest known occurrence of this species in Mexico and approximately 6,000 km northwest of the type locality (municipality of Fortaleza, state of Ceará, Brazil). Comparative morphometric data on diagnostic taxonomic characters of this species are presented.
Aves, Accipitridae, Spizaetus tyrannus (Wied, 1820): new records in the Quadrilátero Ferrífero region, Minas Gerais, Brazil
Authors: Salvador-Jr. Luiz Fernando , Canuto Marcus , Carvalho Carlos Eduardo Alencar , Zorzin Giancarlo
Published: December 2016

The Black Hawk-Eagle Spizaetus tyrannus (Wied, 1820) is a typical forest raptor classified as an endangered species in the state of Minas Gerais, southeast Brazil. Threats include deforestation and fragmentation of forest areas. Although the present investigation points 16 new records of the species in the Quadrilátero Ferrífero, it is noteworthy that the advance of mining activity and expansion of forestry of Eucalyptus spp. in this region are subtracting the forest remnants and increasingly reducing available habitats for this predator inside its limits.
Angiosperms, Pachaiyappa’s College, Chennai, Tamil Nadu, India
Authors: Udayakumar Muthulingam , Ayyanar Muniappan , Sekar Thangavel
Published: December 2016

We provide a checklist of Angiosperms along with the details of life form from a ~ 9.6 ha of non-concreted area of Pachaiyappa’s College (PC) campus, Chennai, Tamil Nadu state, India. This area harbors 256 species belonging to 212 genera in 71 families. Families with maximum number of species include Fabaceae (31 species) followed by Malvaceae (15), Euphorbiaceae (13), Apocynaceae (12), Acanthaceae and Poaceae (11 each), Bignoniaceae and Rubiaceae (eight each) and Arecaceae, Moraceae, Rutaceae and Verbenaceae (seven each). The surveyed area represents a remnant of tropical dry evergreen forest (TDEF), as a substantial number of species collected in the present study belong exclusively to the Coromandel Coast (CC) TDEFs. PC is still preserving the biodiversity by means of strict rules and regulations enforced for the maintenance of the college premises.
Reptilia, Squamata, Gymnophthalmidae, Arthrosaura reticulata (O’Shaughnessy, 1881): distribution extension and new state record
Authors: Mott Tamí , Arruda Luana Aparecida Gomes de , Silva Anelise Figueiredo , Silva Jacqueline Pimentel , Kawashita-Ribeiro Ricardo Alexandre , Carvalho Marcos André de
Published: December 2016

Arthrosaura reticulata (O´Shaugnessy, 1881) is reported from two localities in Mato Grosso, Brazil. It represents the first state record for the species, extending its known distribution in 830 km southeastern of the southernmost record in the state of Amazonas and 470 km eastern of the state of Rondônia, the southernmost record of the species.
Twelve Tips for Curriculum Sharing and Implementation: Don’t Reinvent the Wheel
Authors: Gill Anne C. , West Courtney , Watzak Bree , Quiram Barbara , Pillow Tyson , Graham Lori
Published: December 2016

This article was migrated. The article was marked as recommended. In this era of decreased funding, academic health centers have found that sharing educational best practices is a responsible way to allocate resources as well as lead to new innovations and venues for scholarship. While much has been written about sharing these practices via large databases and public dissemination there is a paucity of information regarding externally imposed partnerships explicitly created to facilitate the sharing of curriculum. Two medical schools in Texas partnered in response to an NIH request for proposals that focused on curriculum sharing. This article details twelve tips learned from this five-year partnership and revolves around two best practices successfully shared, adapted, and then implemented. Practice one is a workshop that targets implicit bias in healthcare and how it impacts patient care. Practice two is a large scale, mass casualty simulation that capitalizes on interprofessional team delivery of health care. Don't reinvent the wheel; share instead.
Realismos Autoritário e Liberal: Aspectos da Imaginação sobre Representação Política em Fins do Século XIX e Princípios do XX
Authors: Hollanda Cristina Buarque de , Coser Ivo
Published: December 2016

RESUMO O artigo explora a premissa de contraste estrito entre “idealistas utópicos” e “orgânicos” suposta por autores que, a despeito de importantes diferenças analíticas e geracionais, se alinham num dos mais destacados cânones do pensamento político brasileiro: Oliveira Vianna, Guerreiro Ramos e Wanderley Guilherme dos Santos. No lugar do rígido dualismo, sugerimos importantes afinidades entre os ditos utópicos e orgânicos. Atentos ao tema da representação política, abordaremos os dois universos intelectuais em questão a partir das obras dos liberais José de Alencar, Assis Brasil e Gilberto Amado, de um lado, e dos autoritários Alberto Torres e Oliveira Vianna, de outro. A nosso ver, os dois grupos de autores convergem no diagnóstico sobre a condição sociológica nacional (clânica e parental) e também na sua imaginação de futuro (afinada com as expectativas de unidade nacional e iniciativa política do Estado). O contraste inequívoco entre os grupos reside sobretudo nos diferentes atores e estratégias de ativação estatal: entre os liberais, o parlamento opera conflito desejável entre as partes que disputam concepções de interesse público; entre os autoritários, a razão de Estado é própria de um sujeito cognoscente privilegiado, o governante, a quem cabe imprimir unidade às cenas social e política.
Pediatric vascular trauma in Manaus, Amazon - Brazil
Authors: COSTA CLEINALDO DE ALMEIDA , SOUZA JOSÉ EMERSON DOS SANTOS , ARAÚJO ANTÔNIO OLIVEIRA DE , MELO FLÁVIO AUGUSTO OLIVA , COSTA ISABELLE NASCIMENTO , KLEIN PAULO HENRIQUE
Published: December 2016

ABSTRACT Objective: to assess the incidence of pediatric vascular injuries in patients treated at the Emergency Room of the Eastern Children's Hospital, in Manaus. Methods: we conducted a retrospective study of pediatric patients who suffered vascular injuries treated between February 2001 to February 2012. Results: we studied 71 patients, predominantly male (78.87%), with a mean age of 7.63 years. The predominant mechanism of injury was stab wound in 27 patients (38.03%). The average hospital stay was 10.18 days; 16 patients required care in intensive care unit, with average stay of 8.81 days. The main injuries occurred in the extremities, the upper limb being the most affected, with lesions of the ulnar artery in 13 (15.66%) and radial in 10 (12.04%). The mostly applied procedure was vascular exploration 35 (32.4%). Complications occurred in nine patients (12.68%). Mortality was 1.4%, in one patient with a lesion of the common iliac vein and the inferior vena cava due fall from height. Conclusion: pediatric vascular injury occurred predominantly in the extremities. The dimensions of the injured vessels made surgical correction more complex and increased complication rates, particularly amputations.
Rupture of celiac trunk aneurysm in patient with Behçet Disease
Authors: Lucas Márcio Luís , Frankini Tiago , Frankini Ângelo , Aerts Newton , Tourinho Tatiana Freitas
Published: December 2016

ABSTRACT We report a case of a ruptured aneurysm of the celiac trunk in a 32-year-old, male patient with Behçet Disease (BD). Aneurysm resection was performed and the patient is well during a follow up of 32 months. To our knowledge, this is the first reported case of a ruptured celiac trunk aneurysm successfully treated in a patient with BD.
Thoracic damage control surgery
Authors: Gonçalves Roberto , Saad Jr Roberto
Published: December 2016

ABSTRACT The damage control surgery came up with the philosophy of applying essential maneuvers to control bleeding and abdominal contamination in trauma patients who are within the limits of their physiological reserves. This concept was extended to thoracic injuries, where relatively simple maneuvers can shorten operative time of in extremis patients. This article aims to revise the various damage control techniques in thoracic organs that must be known to the surgeon engaged in emergency care.
Tensile Strength of Resin Cements Used with Base Metals in a Simulating Passive Cementation Technique for Implant-Supported Prostheses
Authors: Falcão Filho Hilmo Barreto Leite , Ribeiro Ricardo Faria , Souza Raphael Freitas de , Macedo Ana Paula , Almeida Rossana Pereira de
Published: December 2016

Abstract The aim of this study was to analyze the tensile strength of two different resin cements used in passive cementation technique for implant-supported prosthesis. Ninety-six plastic cylinders were waxed in standardized forms, cast in commercially pure titanium, nickel-chromium and nickel-chromium-titanium alloys. Specimens were cemented on titanium cylinders using self-adhesive resin cement or conventional dual-cured resin cement. Specimens were divided in 12 groups (n=8) in accordance to metal, cement and ageing process. Specimens were immersed in distilled water at 37 °C for 24 h and half of them was thermocycled for 5,000 cycles. Specimens were submitted to bond strength test in a universal test machine EMIC-DL2000 at 5 mm/min speed. Statistical analysis evidenced higher tensile strength for self-adhesive resin cement than conventional dual-cured resin cement, whatever the used metal. Self-adhesive resin cement presented higher tensile strength compared to conventional dual-cured resin cement. In conclusion, metal type and ageing process did not influence the tensile strength results.
Biological Tissue Response to a New Formulation of a Silicone Based Endodontic Sealer
Authors: Baldasso Flávia Emi Razera , Kopper Patrícia Maria Poli , Morgental Renata Dornelles , Steier Liviu , Figueiredo José Antônio Poli de , Scarparo Roberta Kochenborger
Published: December 2016

Abstract Satisfactory biological behavior is a necessary requirement for clinical application of endodontic materials. In this study, the connective tissue responses to silicone (GuttaFlow 2), epoxy resin (AH Plus) and zinc oxide and eugenol (Endofill) based sealers were compared. Twelve Wistar rats had polyethylene tubes (four per animal) containing one of the tested sealers and empty tubes (negative control) implanted in their subcutaneous tissue. The tubes were randomly placed 2 cm from the spine and at least 2 cm apart from one another. Tissue samples with implants were processed for histological analysis after 7 or 60 days (n=6 animals per period). Inflammatory cells, fibrous condensation and abscess were scored according to their intensity. Friedman, followed by Dunn's post hoc, was used to compare sealers. Differences between the two experimental periods were verified using Mann-Witney U test (p<0.05). At 7 days, most of the histological parameters showed no significant differences amongst groups. Endofill group scored higher than the others for giant cells (o<0.05) and promoted a greater number of samples presenting abscess formation. GuttaFlow 2 tended to show a less intense inflammatory infiltrate compared to the other materials. At 60 days, there were no significant differences between groups in most of the histological parameters evaluated. However, it was observed that Endofill scored higher for macrophages (p<0.05) compared to the control group, and GuttaFlow 2 tended to present lower scores than the others for neutrophils and abscess. GuttaFlow 2 showed proper biological behavior and should be considered adequate for clinical practice.
Bonding of the Polymer Polyetheretherketone (PEEK) to Human Dentin: Effect of Surface Treatments
Authors: Rocha Regina Furbino Villefort , Anami Lilian Costa , Campos Tiago Moreira Bastos , Melo Renata Marques de , Souza Rodrigo Othávio de Assunção e , Bottino Marco Antonio
Published: December 2016

Abstract Polyetheretherketone (PEEK) is a material suitable for frameworks of fixed dental prostheses. The effect of different surface treatments on the bond strength of PEEK bonded to human dentin was evaluated. One hundred PEEK cylinders (3 mm×3 mm) were divided into five groups according to surface treatment: silica coating, sandblasting with 45 μm Al2O3 particles, etching with 98% sulfuric acid for 5, 30 and for 60 s. These cylinders were luted with resin cement onto 50 human molars. First, each tooth was embedded in epoxy resin and the buccal dentin surface was exposed. Then, two delimited dentin areas (Æ:3 mm) per tooth were etched with 35% phosphoric acid and bonded with a two-step self-priming adhesive system. After the luting procedure the specimens were stored in water (24 h/37 °C). Shear bond strength (SBS) was tested using a universal testing machine (crosshead speed 0.5 mm/min; load cell 50 kgf) and failure types were assessed. Stress data (MPa) were analyzed using the Kruskal-Wallis test. Comparison of the proportions of different failure types was performed using the Bonferroni method (p<0.05). Kruskal-Wallis demonstrated that differences among groups were not significant (p=0.187). Mean SBS were as follows: silica coating, 2.12±1.12 MPa; sandblasting, 2.37±0.86 MPa; sulfuric acid 5 s, 2.28±1.75 MPa; sulfuric acid 30 s, 1.80±0.85 MPa; sulfuric acid 60 s, 1.67±0.94 MPa. Adhesive and mixed failures were predominant in all groups. Both physical and chemical surface treatments produced adhesion between PEEK, resin cement and dentin.