bluuebunny/crossref_metadata_2025 huggingface dataset:
La actividad física en los y las jóvenes mexicanos y mexicanas: un análisis comparativo entre las universidades públicas y privadas
Authors: García Rodríguez Jaime , Fonseca Hernández Carlos
Published: November 2019

La actividad físicaen la historiaaparece desde el momento mismo en que el ser humano surge en la faz de la tierra como un personaje con necesidad de movimiento, el cual se ha manifestado desde el principio de la humanidad en varias facetas tales como el movimiento mecánico, laboral y social. Esto ha evolucionado directamente en proporción al desarrollo humano, llegando hasta nuestros días a presentarse como parte vital dentro de la formación de los individuos y como un medio indispensable para alcanzar salud; sin embargo, existe también un sesgo en la práctica de dicha actividad física y deportiva, que ha originado un culto al cuerpo basado en un posmodernismo influenciado por los medios masivos de comunicación y estándares de una supuesta belleza físicaen ocasiones inalcanzable a la realidad humana; lo que ha ocasionado la presencia de problemas físicos, biológicos, pero de igual manera psicológicos, que repercuten en la autoestima y autoimagen de la población joven y adolescente, que se encuentra en busca de su identidad. Los y las jóvenes actualmentese encuentran influenciados por un estilo de vidadominado por la modernidad y los avances tecnológicos, lo que deriva en una vida sedentaria que produce efectos nocivos en todos los sentidos y todos los ámbitos; lo cual aunado a programas de un sistema institucional educativoy deportivo establecido con innumerables carencias,nos lleva a complicar más la situación, donde se añaden factores perjudiciales que abarcan desde la ignorancia, la incapacidad e intereses personales, que no nos ayudan para edificar alternativas que comiencen a funcionar.Es primordial el establecer una solución pronta y efectiva encaminada en la sistematización de una actividad física adecuada basada en argumentos científicosy métodos acordes,que nos puedan proveer de los diversos beneficios que su práctica otorga y nos ayuden a detener el proceso de deterioro físico al cual el ritmo de vida actual no arroja.
Impacto del modelo del “juego a la salud” en los estilos de vida saludables de estudiantes de primaria
Authors: Álvarez Bogantes Carlos
Published: November 2019

El propósito de este artículo fue el de evaluar el efecto de una intervención interdisciplinaria en los hábitos de alimentación y la actividad física de niños y niñas de tercer grado. Diseño del estudio: Un diseño cuasi-experimental utilizado a través de 4 meses. Sujetos: tomaron parte en el estudio 27 niños y 32 niñas con edades promedio de 9.2 años. La intervención fue conducida por la maestra de grado, el maestro de cómputo, la maestra de educación para la vida en familia y el profesor de educación física, quienes proveyeron al grupo experimental con  4 clases académicas y de educación física en el área de nutrición y actividad física utilizó el programa Del “Juego a la Salud ”. Resultados: Los niños y niñas en el grupo de intervención  tuvieron un incremento significativo en el conocimiento, y en el tiempo reportado en actividad física (p<.05) a través del  reporte dirigido. Además, ellos mostraron  un mejoramiento en el consumo de frutas y vegetales (p<.01). Con respecto a la actitud de cambio hacia la actividad física, las mujeres de la intervención mostraron cambios  significativos. Conclusiones: El programa Del Juego a la Salud, mejoró el tiempo dedicado a la actividad física y al consumo de frutas y vegetales. Este estudio demostró ser práctico y que podría ser fácilmente incorporado al contexto educativo. Este programa puede mejorar el conocimiento en salud, en la actitud de cambio, y en las prácticas en nutrición y actividad física.
El equipo de investigación: un reto y una realidad
Authors: Alfaro Rodríguez Magdalena , Gamboa Jiménez Alejandra , Jiménez Sánchez Susana , Martín Pérez Jorge R. , Ramírez González Andrea
Published: November 2019

Recibido 10 de setiembre de 2009 • Aceptado 02 de diciembre de 2009 • Corregido 09 de diciembre de 2009

 

En este ensayo se relatan los retos iniciales, los procesos de trabajo, la conformación como equipo y los aprendizajes obtenidos por investigadores e investigadoras del equipo interdisciplinario del Proyecto Perfiles, Dinámicas y Desafíos de la Educación Costarricense del Centro de Investigación y Docencia en Educación (CIDE) de la Universidad Nacional, en su tercera etapa. Se analiza cómo el trabajo cooperativo y el liderazgo compartido como equipo, hicieron exitoso al proceso de investigación.
Consideraciones básicas del pensamiento complejo de Edgar Morin, en la educación
Authors: Pereira Chaves José Miguel
Published: November 2019

Recibido 18 de noviembre de 2009 • Aceptado 02 de diciembre de 2009 • Corregido 09 de mayo de 2010

 

 

Este ensayo consiste en una breve descripción y un análisis del pensamiento complejo de Edgar Morin; para ello se hace mención al enfoque sistémico el cual se refiere a la interconexión y a las interacciones entre los objetos, las personas y el ambiente como un todo, lo cual sirve de fundamento para la propuesta educativa, en la que el conocimiento se debe abordar de manera integral y no fragmentado. Por lo anterior, el conocimiento humano debe fomentar la toma de conciencia de que somos tan sólo una parte componente de un sistema más general (complejo, y en constante interacción), en el que la educación puede ser el medio efectivo para que los alumnos desarrollen la capacidad de comprender otros sistemas complejos, además de los seres vivos. Aquí cobran importante interés las “nuevas ciencias” y las humanidades.
Pedagogía, diversidad y lenguaje: develando los colores en miradas aprendientes
Authors: Castillo Cedeño Ileana , Flores Davis Luz Emilia , Jiménez Corrales Rafael Esteban , Perearnau Torras Mariángeles
Published: November 2019

Recibido 26 de octubre de 2009 • Aceptado 02 de diciembre de 2009 • Corregido 17 de febrero de 2010

 

 

 

En el constante cambio que vivimos, la Pedagogía, en tanto ciencia de la educación, ciencia de la relacionalidad entre seres humanos, es el producto de acuerdos, de procesos comunicativos, procesos socioculturales entrelazados de forma compleja. La atención a la diversidad es una preocupación creciente en ambientes y sociedades plurales, y el lenguaje, como rasgo cultural permite describir nuestras circunstancias y reflexionar sobre ellas para comprenderlas, redimensionar el presente, valorar el pasado e imaginar el futuro. Si tenemos en cuenta que el habla es sólo una de las manifestaciones del lenguaje, si las diversas formas de expresión del cuerpo constituyen formas de lenguaje, se impone la necesidad de pensar cómo nos comunicamos en los procesos pedagógicos.
La importancia de la educación ambiental ante la problemática actual
Authors: Martínez Castillo Róger
Published: November 2019

Recibido 15 de febrero de 2010 • Aceptado 17 de marzo de 2010 • Corregido 05 de abril de 2010

 

El sistema de desarrollo dominante, con sus políticas neoliberales y enfoques mercado-céntricos contribuye a agravar los problemas socio-ambientales, bajo un contexto de la globalización del mercado. Por eso, la preocupación por el manejo sustentable del ambiente, hace imperiosa la necesidad de estructurar una educación ambiental que forme e informe acerca de esta problemática. En este sentido, la educación ambiental viene a constituir el proceso educativo que se ocupa de la relación del ser humano con su ambiente (natural y artificial) y consigo mismo, así como las consecuencias de esta relación. De esta manera, la educación ambiental debe constituir un proceso integral, que juega su papel en todo el entramado de la enseñanza y el aprendizaje. Para ello, es necesario establecer un proceso educativo que cuestione la relación de cualquier tema o actividad del ser humano, dentro de un análisis de la importancia o incidencia en la vida social y ambiental, como es la parte pedagógica y su esencia política.
La comunicación en el aula de sétimo año
Authors: Alfaro Rodríguez Magdalena , Gamboa Jiménez Alejandra , Jiménez Sánchez Susana , Martín Pérez Jorge , Ramírez González Andrea , Vargas Dengo Marie Claire
Published: November 2019

Recibido 31 de julio de 2009 • Aceptado 14 de setiembre de 2009 • Corregido 17 de junio de 2010

 

 

 

Reflexiones sobre la comunicación en el proceso de aprendizaje en el nivel del sétimo año de la educación secundaria, con base en los abordajes metodológico y pedagógico, apreciados en investigación de un equipo interdisciplinario del CIDE de la UNA, con el objetivo de construir el “Perfil de desempeño docente para el 7mo año de la educación costarricense”.

Se evidencia el protagonismo del cuerpo docente para lograr vínculos comunicativos favorables al proceso de aprendizaje, donde no bastaba con captar la atención y el interés del estudiantado a través de variadas y sistemáticas motivaciones, sino también la honestidad, receptividad, ejemplo personal e involucramiento en el quehacer, problemáticas y aspiraciones del estudiantado.
El espíritu creativo: una experiencia de investigación en educación superior
Authors: Piñeiro Ruiz Milagro
Published: November 2019

Recibido 21 de julio de 2010 • Aceptado 31 de agosto de 2010 • Corregido 24 de octubre de 2010

 

El siguiente artículo presenta una experiencia de investigación desarrollada durante el I ciclo de 2009 con los estudiantes del curso Didáctica general, en la Sede de Occidente de la Universidad de Costa Rica. Esta experiencia pretende promover la creatividad de los estudiantes para la creación de su propia didáctica, a través del desarrollo de dos objetivos del curso: analizar la acción didáctica desde diferentes enfoques y determinar la relación de la didáctica con las innovaciones educativas y su vinculación con la cultura profesional. Como estrategia para la evaluación de la experiencia se utilizó la
Aportes de las neurociencias para el desarrollo de estrategias de enseñanza y aprendizaje de las Matemáticas
Authors: Mogollón Eddy
Published: November 2019

Recibido 27 de setiembre de 2010 • Aceptado 03 de noviembre de 2010 • Corregido 21 de noviembre de 2010  El presente trabajo tiene como objetivo desarrollar algunas estrategias generadas a partir de las investigaciones en neurociencias. El propósito es contribuir con la enseñanza y aprendizaje de las Matemáticas. Se argumentó sobre la interrelación de la enseñanza compatible con el cerebro, así como sobre las estructuras cerebrales con el pensamiento en matemático. Se desarrollaron estrategias tomando en consideración niveles que abarcan lo cognitivo, semiótico, lenguaje, la afectividad y la superación de las fobias a la asignatura. La conclusión fundamental fue el imperante requerimiento educativo en el futuro próximo de un nuevo docente, cuya formación pedagógica debe incluir el conocimiento sobre la función cerebral, sus estructuras y sus implicancias con la educación, así como un cambio en la pedagogía y estructura currícular en la enseñanza de las Matemáticas.
Una experiencia de educación ambiental con estudiantes de un colegio rural de Costa Rica
Authors: Sisfontes Guilarte Pablo
Published: November 2019

Recibido 05 de abril de 2010 • Aceptado 24 de junio de 2010 • Corregido 28 de julio de 2010

 

Este artículo describe una experiencia pedagógica de Educación Ambiental desarrollada en un colegio rural de Costa Rica con estudiantes de IX año, caracterizada por la dinámica de taller, en la cual destaca la participación en la construcción de iniciativas para enfrentar la problemática ambiental detectada por los jóvenes en sus respectivas comunidades. El artículo persigue contribuir con la construcción de un modelo pedagógico autogestionario de capacitación y formación de jóvenes en los sectores ambientales, turísticos y agrícolas, desde la convicción de que la educación se constituye en una alternativa indispensable para la comprensión y solución de la problemática ambiental.
El placer de aprender
Authors: Flores Davis Luz Emilia
Published: November 2019

Recibido 22 de marzo de 2010 • Aceptado 24 de junio de 2010 • Corregido 06 de julio de 2010

 

La evolución de una educación centrada en la enseñanza, a una perspectiva de aprendizaje, constituye un cambio de paradigma, así lo afirma la autora de este artículo, quien invita a asumir el placer de aprender como dinamizador de la construcción de sentidos. Asevera que la educación debe transitar de la repetición acrítica de contenidos, a la generación de aprendizaje placentero, y que la búsqueda de alternativas para una educación que supere el paradigma tradicional, lleva a la necesidad de promover una auténtica participación gozosa.
La educación superior en el contexto de la posmodernidad: Entendimiento y reconciliación
Authors: Barrantes Montero Luis Guillermo
Published: November 2019

Recibido 01 de diciembre de 2010 • Aceptado 09 de marzo de 2011 • Corregido 05 de junio de 2011

 

 

 

El propósito de este trabajo es fomentar la reflexión y la toma de conciencia acerca de la necesidad y conveniencia de buscar un mayor acercamiento entre los docentes, las autoridades y los estudiantes universitarios con respecto al modo en que se concibe la educación superior en el momento actual, su razón de ser y sus metas. Para ello, se compara la perspectiva modernista y postmoderna de la sociedad y de la educación, a fin de evidenciar los principales puntos de divergencia y los posibles canales de consenso. Se concluye proponiendo la apertura de espacios para lograr acuerdos de intersubjetividad y, así, alcanzar el objetivo propuesto.
Reflexiones en torno a la vinculación de la educación y el género
Authors: Vargas Jiménez Ileana
Published: November 2019

Recibido 18 de enero de 2011 • Aceptado 09 de marzo de 2011 • Corregido 05 de mayo de 2011

 

El siguiente artículo plantea una reflexión acerca de cómo la educación, desde la escuela, propicia, a partir del currículo oficial y del currículo oculto, una serie de elementos que tienden a hacer diferencias en cuanto a género. Además, se plantean una serie de aspectos tales como la televisión, las prácticas pedagógicas de los grupos de docentes, que inciden directamente en la discriminación sexista. Se muestran, también, algunas recomendaciones que aportan de investigadores para contrarrestar la discriminación por género. Finalmente se presentan las conclusiones.
Aprendizaje de la escritura en lengua no materna: Casos de niños tarahumaras
Authors: Viramontes Anaya Efrén , Morales Sifuentes Lylia Ana , Burrola Márquez Luis Manuel
Published: November 2019

Recibido 01 de diciembre de 2010 • Aceptado 09 de marzo de 2011 • Corregido 19 de abril de 2011

 

Resumen. Esta investigación analiza el desarrollo de la escritura en español de niños indígenas tarahumaras bilingües (del Estado de Chihuahua, México), desde varias perspectivas: la psicogenética, relacionada con el avance en el proceso de construcción del sistema de escritura de los niños investigados; la social, mediante al análisis del contexto familiar, cultural y el entorno del asentamiento de convivencia de los mismos; y la pedagógica, aunque más breve, a través del ambiente áulico dentro de dos escuelas muy diferentes: una regular y otra indígena. El planteamiento central de la investigación giró en torno a la percepción de los múltiples factores que se relacionan con el aprendizaje de la escritura, en un intento de escudriñar analíticamente los elementos posibles de afectación en el proceso referido. La metodología cualitativa utilizada posibilitó, mediante el estudio de casos, la observación, la entrevista, la videograbación y el análisis de los cuadernos de los niños, percibir situaciones y rescatar evidencias que, mediante el estudio transversal de eventos, personas y contextos, dieron como resultado interpretaciones sobre los factores sociales, culturales, cognitivos y pedagógicos que se percibieron asociados al aprendizaje de la escritura de una lengua que no es la materna, en niños indígenas migrantes establecidos en un medio distinto al de sus ancestros. Se atiende principalmente a la hipótesis de que, en las circunstancias de los casos estudiados, es más conveniente que aprendan a escribir primero en su segunda lengua y, posteriormente, en la materna, si así lo requieren.
Los diseños de método mixto en la investigación en educación: Una experiencia concreta
Authors: Pereira Pérez Zulay
Published: November 2019

Recibido 14 de octubre de 2010 • Aceptado 09 de marzo de 2011 • Corregido 02 de junio de 2011

 

La utilización de los diseños de método mixto se constituyen, día a día, en una excelente alternativa para abordar temáticas de investigación en el campo educativo. Este ensayo plantea una revisión acerca de dichos diseños y los ejemplifica con una experiencia concreta de investigación realizada por la propia autora, en la que fue aplicado un diseño de método mixto para una temática en el campo educativo.
Evaluación de la organización académico administrativa con base en la metodología de los sistemas suaves: El caso de la licenciatura en turismo
Authors: Cardoso Espinosa Edgar Oliver , Ramos Mendoza José Roberto , Cerecedo Mercado María Trinidad
Published: November 2019

Recibido 20 de octubre de 2010 • Aceptado 09 de marzo de 2011 • Corregido 2 de abril de 2011

 

El objetivo de la investigación fue evaluar, con un enfoque sistémico, la organización académico administrativa de tres programas de licenciatura en turismo, con la finalidad de identificar las características que estos presentaban respecto a los criterios del Consejo para la Acreditación de la Educación Turística (CONAET) y TedQual (Tourism Education Quality), para acceder a la certificación nacional e internacional. El cuestionario y la guía de observación fueron los instrumentos para recopilar la información necesaria, la cual fue organizada con un enfoque cualitativo (mediante el Atlas Ti) y cuantitativo (a través de la estadística descriptiva). La principal conclusión fue que la Licenciatura en Turismo, ofrecida por la Escuela Superior de Turismo (EST), cumple con los criterios de certificación. Se considera, por tanto, que sus instalaciones y el programa ofertado se encuentran de acuerdo con los lineamientos de certificación, en tanto que la Universidad el Valle de México (UVM) y la Escuela Bancaria y Comercial (EBC) presentan serias deficiencias respecto a los criterios establecidos por estos organismos.
La incidencia de las competencias del profesorado universitario en la calidad de la educación promovida
Authors: España Chavarría Carolina
Published: November 2019

Recibido 05 de mayo de 2010 • Aceptado 31 de agosto de 2010 • Corregido 23 de agosto de 2010

 

El siguiente ensayo intenta evidenciar la incidencia que subyace entre las competencias del profesorado y la calidad educativa ofertada desde una dimensión ética, la cual, a diferencia de la dimensión técnica, es la responsable de permitirle al colectivo docente que: a) promueva aprendizajes a partir del procesamiento de la información hacia conocimientos prácticos, claros y relevantes en la vida del estudiantado, y b) construya su propio sentido de la educación.
Lifestyles of Ukrainian capitalists as a demonstration of social subjectivity in society
Authors: Rakhmanov Oleksandr
Published: November 2019

The article analyzes the lifestyles Ukrainian capitalists. Large owners of Ukraine by the symbolic value of the purchased luxury goods or exclusive services strive to strengthen its social subjectivity.
Demonstrative consumption of Ukrainian capitalists is encountering strong resistance from society, because in public opinion is dominated by the notion that money is only way to achieve the vital success.
Theoretical aspects of state social security
Authors: Sidorchuk Anatolii
Published: November 2019

Theoretical bases of social security are presented, that, coming from logic of research, expresses ability of the state by the specially created collective insurance funds to satisfy the necessities of payers of insurance payments and relievers taking into account private and public interests.
Program and target provision for the solution of urgent problems of overcoming and prevention of poverty of working population
Authors: Melnyk Serhii , Kosheleva Galyna , Gaevska Nadiia
Published: November 2019

The article deals with possible settlement of problems of overcoming and prevention of poverty of working population with the help of usage of program-aim approach. The given propositions on optimization of structures of management, which are responsible for introduction of state target oriented of poverty overcoming, including those of them who work, ground the necessity of reforming of labor remuneration with the aim to raise incomes of working population.
The development of civil society in Ukraine as an object of the state influence
Authors: Melnyuchenko Viktor
Published: November 2019

Article is devoted to the determination of the content of civil society, the assessment on this basis of domestic practice in the part of necessity of boundaries and tools of state participation in the development of civil society.
Outlined contradictions of views on civil society and its development, formulated certain proposals on perspectives of development of civil society and participation in promoting of this development of the Ukrainian state.
Near Real-Time Surveillance to Assess the Safety of the 9-Valent Human Papillomavirus Vaccine
Authors: Donahue James G. , Kieke Burney A. , Lewis Edwin M. , Weintraub Eric S. , Hanson Kayla E. , McClure David L. , Vickers Elizabeth R. , Gee Julianne , Daley Matthew F. , DeStefano Frank , Hechter Rulin C. , Jackson Lisa A. , Klein Nicola P. , Naleway Allison L. , Nelson Jennifer C. , Belongia Edward A.
Published: November 2019

BACKGROUND AND OBJECTIVES:

Human papillomavirus is the most common sexually transmitted infection in the United States and causes certain anogenital and oropharyngeal cancers. The 9-valent human papillomavirus vaccine (9vHPV) provides protection against additional types not included in the quadrivalent vaccine. We conducted near real-time vaccine safety surveillance for 24 months after the vaccine became available in the Vaccine Safety Datalink.

METHODS:

Immunizations and adverse events were extracted weekly from October 2015 to October 2017 from standardized data files for persons 9 to 26 years old at 6 Vaccine Safety Datalink sites. Prespecified adverse events included anaphylaxis, allergic reaction, appendicitis, Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, injection site reaction, pancreatitis, seizure, stroke, syncope, and venous thromboembolism. The observed and expected numbers of events after 9vHPV were compared weekly by using sequential methods. Both historical and concurrent comparison groups were used to identify statistical signals for adverse events. Unexpected signals were investigated by medical record review and/or additional analyses.

RESULTS:

During 105 weeks of surveillance, 838 991 doses of 9vHPV were administered. We identified unexpected statistical signals for 4 adverse events: appendicitis among boys 9 to 17 years old after dose 3; pancreatitis among men 18 to 26 years old; and allergic reactions among girls 9 to 17 years old and women 18 to 26 years old after dose 2. On further evaluation, which included medical record review, temporal scan analysis, and additional epidemiological analyses, we did not confirm signals for any adverse events.

CONCLUSIONS:

After 2 years of near real-time surveillance of 9vHPV and several prespecified adverse events, no new safety concerns were identified.
Unique Needs of the Adolescent
Authors: Alderman Elizabeth M. , Breuner Cora C. ,   COMMITTEE ON ADOLESCENCE, Grubb Laura K. , Powers Makia E. , Upadhya Krishna , Wallace Stephenie B.
Published: November 2019

Adolescence is the transitional bridge between childhood and adulthood; it encompasses developmental milestones that are unique to this age group. Healthy cognitive, physical, sexual, and psychosocial development is both a right and a responsibility that must be guaranteed for all adolescents to successfully enter adulthood. There is consensus among national and international organizations that the unique needs of adolescents must be addressed and promoted to ensure the health of all adolescents. This policy statement outlines the special health challenges that adolescents face on their journey and transition to adulthood and provides recommendations for those who care for adolescents, their families, and the communities in which they live.
THE EFFECT OF FINANCIAL INCLUSION AND BANKING BEHAVIOR ON HOUSEHOLD DEBT BEHAVIOR
Authors: HERISPON HERISPON
Published: November 2019

This study aims to examine the effect of financial inclusion from the dimensions of access, user, quality, wealth on bank behavior and debt behavior and the indirect influence of each dimension of financial inclusion on bank behavior and household debt behavior. With population areas and samples in the city of Pekanbaru, Riau, Indonesia.The research focused on the demand side in banking services, namely consumer credit services to households. Using a purposive sampling method with a total sample of 303 household units in the city of Pekanbaru.The analysis tool used in the study was SEM-WarpPLS version 6.From this study the authors found that access, user, quality, wealth had a positive effect on the behavior of household debt, then the authors found that access, user, quality had a positive effect on bank behavior, then found that access, user, quality, wealth had an indirect positive effect towards debt behavior through mediating bank behavior.It was concluded from this study that the behavior of banks as mediating variables can reduce the direct influence of financial inclusion on the behavior of household debt.
PENGARUH KEDALAMAN JANGKAUAN PEMBIAYAAN TERHADAP KEBERLANJUTAN KEUANGAN LEMBAGA KEUANGAN MIKRO SYARIAH
Authors: RE RAMEL YANUARTA , HULWATI HULWATI , ROZALINDA ROZALINDA
Published: November 2019

Analysis of the sustainability of the microfinance institutions cannot be separated from its outreach. This study aims to analyze the effect of the depth of outreach on financial sustainability in the Koperasi Jasa Keuangan Sharia Baitul Maal wa Tamwil (KJKS BMT) kelurahan Kota Padang. This study is an analysis of causality. The analysis was carried out for two years of financial statements, 2014 and 2015. Samples were taken using a purposive sampling approach. The financial sustainability issues are analyzed with two variables, namely return on assets (ROA) and non-performing financing (NPF) which are used as dependent variables in multiple regression models. As independent variables, the average value of financing provided by the KJKS BMT kelurahan Kota Padang is used as a proxy for the level of the depth of outreach and several other control variables. The results of this study reveal that there is a trade-off between the depth of outreach from financing services to poor households to the BMT KJKS kelurahan Kota Padang and financial sustainability as is the case in conventional microfinance institutions. So, naturally in practice there will be reluctance in the KJKS of BMT Kota Padang urban village to provide financing services to poor households because of their negative financial performance.
SHARIA CUSTOMER BEHAVIOR: PERILAKU KONSUMEN DALAM BELANJA ONLINE
Authors: SOLIHIN SOLIHIN , AZWAR WELHENDRI
Published: November 2019

This study was aimed to find out and analyzed the factors that encourage the consumer especially among the students who were being the target market of marketer to purchase the product which sold via online in terms of the Islamic Marketing Concept. Research methodology in this research is descriptive quantitative with the primer data and secunder data. The population of the study was the students of Economy Faculty. Meanwhile, the sample which used was 100 respondents. The result of the study showed that from that factors, the dominant factor which encouraged the students of Economy Faculty in Padang City to buy the product via online in terms of Islamic Marketing Concept was : Useful indicator of the goods/product with the mean 4.03, next variables indicator which had major role in encouraging the consumer in online shopping in terms of Islamic Marketing Concept was the indicator of the product was free from gambling with the mean score 3.90, next, it was followed by the indicator of the product is halal with the mean score 3.89, after that, the indicator that there is guarantee of the product/trusted with the mean score 3.55, the last was the indicator free from decetion with the mean score 3.51.
Human Factors Training: Structured Management Airway Response Team (SMART) Approach Aims to Improve Patient Safety
Authors: Dravid Ravi , Balla Sunita , Radhakrishna Subrahmanyan , Netke Bhagyashree , Gauthama Priya , Swami Ajay , Dale Trevor , Mendonca Cyprian
Published: November 2019

This article was migrated. The article was marked as recommended. Background: Technical skills and human factors are the pillars of effective team work in every given situation. This is more evident in professions where an error can transform into a catastrophe in seconds and minutes. The avaition industry and medical specialty have been witness to this predicament. Difficult airway is one such realm in anaesthetics where a sound management strategy coupled with excellent team dynamics hold the key to a successful outcome. Hence, we piloted the concept of Structured Management Airway Response Team with 'predesignated roles' to improve airway safety. Methods: A training course was developed to teach non technical skills to teams of anaesthetist and anaesthetic assistants. The course was evaluated for its effectiveness at changing delegates' attitudes to 'airway safety'. Delegates were asked to complete pre and post course questionnaires designed by panel of airway experts where they were asked to mark their response to eight question on a visual analogue scale of 0-100. Results: The results indicated a positive change as the visual analogue scores were significantly higher in the post-course questionnaire (p = 0.001 for one question and = <0.001 for other seven questions). Conclusion: We infer that teaching Human Factors to teams involving anesthetist and anaesthetic assistants would improve attitudes to airway management and promote patient safety.
Monitoring of cytogenetic instability by micronuclei assay of both immunocompetent and non-immunocompetent cells in tick-borne encephalitis patients depending on variants of glutathione-S-transferase genes in the genotype
Authors: Ilyinskikh Nikolay Nikolaevich , Ilyinskikh Ekaterina Nikolaevna , Zamyatina Evgenia Vladimirovna , Lee Svetoslava Vyacheslavovna
Published: November 2019

Aim of this study was to study the dynamics of the frequency of cytokinesis-blocked T-lymphocytes with micronuclei in peripheral blood and the frequency of buccal micronucleated epithelium cells for a period of half a year in patients with acute tick-borne encephalitis, depending on burden of active and inactive variants of glutathione-S-transferase genes (GSTM1 and GSTT1) in the patient's genotype. We carried out micronucleus assay in immunocompetent and non-immunocompetent cells in 54 patients with acute tick-borne encephalitis and 35 healthy persons (control) residing in the Tomsk and Tyumen regions. To analyze the frequency of cytokinesis-blocked micronucleated T-lymphocytes was used venous peripheral blood as material for phytohemagglutinin-stimulated cultures, and to study the frequency of buccal micronucleated cells, samples of the buccal mucous membrane epithelial cells were obtained. To carried out both techniques of micronucleus assay, cytological preparations were prepared, which were stained using the Giemsa or Felgen methods. The material for the study was obtained repeatedly during admission of patients to treatment, and also after 1 week, 1, 3 and 6 months.  Polymerase chain reaction was used to analyze the alleles of the GSTM1 and GSTT1 genes. As a result of this analysis was found a significant increase in the frequency of micronucleated cells in tick-borne encephalitis patients compared with the control group. In addition, the frequency of cytokinesis-blocked micronucleated T-lymphocytes was increased significantly higher than the one of micronucleated buccal cells. The most significant and prolonged increase in the frequency of micronucleated cells was associated with the mutant inactive variants of the genes GSTM1 (0/0) and GSTT1 (0/0). In the patients with burden the inactive forms of these genes, the cytogenetic instability of the cytokinesis-blocked blood T-lymphocytes could persist for up to six months. In case of buccal cells, the frequency of micronucleated cells was close to the one in the control group as early as 1-3 months after a course of treatment. Conclusion. It was found that the most increased and prolonged frequency of cytogenetically instable cells persisted in cytokinesis-blocked T-lymphocytes of peripheral blood of patients with tick-borne encephalitis who were carriers of the genotype with inactive variants of  both GSTM1 (0/0) and GSTT1 (0/0 ) glutathione-S-transferase genes.
Yersinia pseudotuberculosis-derived adhesins
Authors: Byvalov A. A. , Konyshev I. V.
Published: November 2019

Around fifteen surface components referred to adhesins have been identified in Yersinia pseudotuberculosis combining primarily microbiological, molecular and genetic, as well as immunochemical and biophysical methods. Y. pseudotuberculosis-derived adhesins vary in structure and chemical composition but they are mainly presented by protein molecules. Some of them were shown to participate not only in adhesive but in other pathogen-related physiological functions in the host-parasite interplay. Adhesins can mediate bacterial adhesion to eukaryotic cell either directly or via the extracellular matrix components. These adhesion molecules are encoded by chromosomal DNA excepting YadA protein which gene is located in the calcium-dependence plasmid pYV common for pathogenic yersisniae. An optimum temperature for adhesin biosynthesis is located close to the body temperature of warm-blooded animals; however, at low temperature only invasin InvA, full-length smooth lipopolysaccharide and porin OmpF are produced in Y. pseudotuberculosis. Several adhesins (Psa, InvA) can be expressed at low pH (corresponds to intracellular content), thereby defining pathogenic yersiniae as facultative intracellular parasites. Three human Yersinia genus pathogens differ by ability to produce adhesins. Y. pseudotuberculosis adherence to host cells or extracellular matrix components is determined by a cumulative adhesion-based activity, which expression depends on chemical composition and physicochemical environmental conditions. It’s proposed that at the initial stage of infectious process adherence of Y. pseudotuberculosis to intestinal epithelium is mediated by InvA protein and “smooth” LPS form. These adhesins are produced in bacterial cells at low (lower than 30°С) temperature occurring in environment from which a pathogen invades into the host. At later stages of pathogenesis, after penetrating through intestinal epithelium, bacterial cells produce other adhesins, which promote survival and dissemination primarily into the mesenteric lymph nodes and, possibly, liver and spleen. At later stages of pathogenesis, after penetrating through intestinal epithelium, bacterial cells produce other adhesins, which promote survival and dissemination primarily into the mesenteric lymph nodes and, perhaps, liver and spleen. Qualitative and quantitative spectrum of Y. pseudotuberculosis adhesins is determined by environmental parameters (intercellular space, intracellular content within the diverse eukaryotic cells).
Intestinal microbiota composition and peripheral blood Th cell subsets in patients with multiple sclerosis
Authors: Abdurasulova I. N. , Tarasova E. A. , Kudryavtsev I. V. , Negoreeva I. G. , Ilves A. G. , Serebriakova M. K. , Ermolenko E. I. , Ivashkova E. V. , Matsulevich A. V. , Tatarinov A. E. , Stoliarov I. D. , Klimenko V. M. , Suvorov A. N.
Published: November 2019

At present, the role of intestinal microbiota in diverse diseases of the central nervous system, including of multiple sclerosis (MS) has been extensively investigated. Self-reactive CD4+ Th1 and Th17 cells specific to myelin-derived antigens play a key role in the MS pathogenesis. Taking into consideration pathogenetic features related to MS development, we examined a relation between intestinal microbiocenosis and abundance of various peripheral blood helper T (Th) cell subsets in MS patients. Objective of the study: to assess prevalence of individual members of the intestinal microbiota in MS patients and analyze a relation with peripheral blood Th cell subsets. Prevalence of symbiotic and opportunistic microbial species was estimated by bacteriological method and real time PCR in 112 MS patients (72 females, 40 males) of varying severity and duration. Th cell subsets (Th1, Th2, Th17, Th1/Th17, Th17/Th22, DP Th17) were analyzed by using multi-color flow cytometry based on Th cell subset-specific surface expression of chemokine receptors. A relationship between individual intestinal microbiota species and severity, duration and rate of MS progression, as well as with the phenotype of immune cells was assessed. It was found that the most significant correlation between percentage of peripheral blood Th cell subsets was observed with prevalence of Lactobacillus spp., Enterococcus spp. and Enterobacter spp. Moreover, prevalence of Enterococcus spp. Th cell composition influenced synergistically or antagonistically together with Enterobacter spp. or Lactobacillus spp., respectively. It is suggested that direct and indirect impact of intestinal microbiota composition on human immune system might contribute to developing novel strategies for treating MS.
Chronic hepatitis b associated without/with a delta agent in Kyrgyzstan (epidemiological situation, clinical features)
Authors: Nogoibaeva K. A. , Tobokalova S. T. , Bekenova D. S. , Nazarbaeva J. N
Published: November 2019

Objective. To compare epidemiological, clinical and laboratory characteristics of chronic hepatitis B (ChHB) associated with/without delta agent (ChHB+DV) study.Materials and methods. The Kyrgyzstan State Reporting Form No. 12 covering 2010–2017 period was examined. For this, 133 and 130 case histories of ChHB and ChHB+DV patients, respectively, were analyzed. The data were statiastically processed by using Microsoft Office Excel software.Results and discussion. Over the 2010–2017 period, prevalence of the “HBV Carrier” (60.4 ) was higher by 20-fold than that one for ChHB [3.8 , 95% CI (2.4–4.0)] and CVHD [3.4 , 95% CI (2.2–3.4)], as the vast majority of patients were not thoroughly examined after detecting HBsAg, and the HBV Carrier was empirically diagnosed at the primary health care units. As a result, routine case definitions for such conditions were revised and an improved system of epidemiological surveillance of viral hepatitis was developed, according to the 2016 WHO recommendations approved by the Ministry of Health of the Kyrgyz Republic (Order No. 524, dated of July 20, 2018). Asthenia was observed in ~60% of patients in both groups, whereas arthralgia — in ~5–10% of patients, more often in those comorbid with ChHB+DV, and myalgia — in as low as ~3% of cases. Impaired central nervous system functions manifested as headache and restless sleep were evenly recorded in about 10–15% of patients, without significant difference between groups. In contrast, dominating dyspeptic manifestations such as poor appetite (72±3.9% vs. 20.6±3.5%, p 0,05), nausea (23.8±3.7% vs. 7.3±2.3%, p 0,05), vomiting (12.3±2.6% vs. 3.3±1.5%, p 0,05) and flatulence (27±3.9% and 13±2.9%, p 0,05) were revealed in ChHB+DV patients. Pain in the right hypochondrium was noted in 52–56% of patients, insignificantly differed between patient groups. Incidence of yellowness of the sclera and skin layers as well as skin itching were recorded by 2–3 and 8 times, respectively, more frequently in ChHB+DV patients. A more profound cytolysis and signs of altered bilirubin metabolism were also more common in HBV patients comorbid with the delta agent. Thus, a more severe ChHB+DV course requires that all patients with primary HBsAg detection were mandatorily examined for anti-HDV antibodies to ensure early diagnostics and timely organization of the secondary and tertiary preventive measures in the Kyrgyzstan.
SIR+A mathematical model for evaluating and predicting 2016–2017 ARVI-influenza incidence by using on the Moscow territory
Authors: Kontarov N. A. , Arkharova G. V. , Grishunina Yu. B. , Grishunina S. A. , Yuminova N. V.
Published: November 2019

Influenza is a major challenge to global healthcare due to its high transmissivity and ability to cause major epidemics. Influenza epidemics and pandemics are associated with changes in the society structure that contribute to the spread of new viral strains in certain environmental and social settings. Currently, influenza is one of the most common global diseases that results in annual epidemics or even pandemics, often leading to lethal outcome. Influenza viruses are uniquely prone to variability via point mutations, recombination and gene reassortment accompanied with changes in their biological properties considered as the main cause of uncontrolled infection spread. Hence, examining cohorts of predisposed individuals by using probability models provides not only additional information about viral outbreaks, but also allows monitoring dynamics of viral epidemics in controlled areas. Understanding influenza epidemiology is crucial for restructuring healthcare resources. Public healthcare service mainly relies on influenza vaccination. However, there are vulnerable cohorts such as elderly and immunocompromised individuals, which usually contain no protective antiinfluenza virus antibody level. Despite advances in the developing vaccines and chemotherapy, large-scale influenza epidemics still continue to emerge. Upon that, no reliable methods for disease prognosis based on rate of ongoing epidemic situation are currently available. Monitoring and predicting emerging epidemics is complicated due to discrepancy between dynamics of influenza epidemics that might be evaluated by using surveillance data as well as platform for tracking influenza incidence rate. However, it may be profoundly exacerbated by mutations found in the influenza virus genome by altering genuine morbidity dynamics. Use of probabilistic models for assessing parameters of stochastic epidemics would contribute to more accurately predicted changes in morbidity rate. Here, an SIR+A probabilistic model considering a relationship between infected, susceptible and protected individuals as well as the aggressiveness of external risks for predicting changes in influenza morbidity rate that allowed to evaluate and predict the 2016 ARVI influenza incidence rate in Moscow area. Moreover, introducing an intensity of infection parameter allows to conduct a reliable analysis of incidence rate and predict its changes.
Ipilimumab and Gemcitabine for Advanced Pancreatic Cancer: A Phase Ib Study
Authors: Kamath Suneel D. , Kalyan Aparna , Kircher Sheetal , Nimeiri Halla , Fought Angela J. , Benson Al , Mulcahy Mary
Published: November 2019

Background

Pancreatic ductal adenocarcinoma (PDAC) remains resistant to chemotherapy and immunotherapy individually because of its desmoplastic stroma and immunosuppressive tumor microenvironment. Synergizing cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4) immune checkpoint blockade with chemotherapy could overcome these barriers. Here we present results of a phase Ib trial combining ipilimumab and gemcitabine in advanced PDAC.

Materials and Methods

This was a single-institution study with a 3 + 3 dose-escalation design. The primary objective was to determine the maximum tolerated dose (MTD). Secondary objectives included determining the toxicity profile, objective response rate (ORR), median progression-free survival (PFS), and overall survival (OS).

Results

Twenty-one patients were enrolled, 13 during dose escalation and 8 at the MTD. The median age was 66 years, 62% were female, 95% had stage IV disease, and 67% had received at least one prior line of therapy. The primary objective to establish the MTD was achieved at doses of ipilimumab 3 mg/kg and gemcitabine 1,000 mg/m2. The most common grade 3 or 4 adverse events were anemia (48%), leukopenia (48%), and neutropenia (43%). The ORR was 14% (3/21), and seven patients had stable disease. Median response duration for the three responders was 11 months, with one response duration of 19.8 months. Median PFS was 2.78 months (95% confidence interval [CI], 1.61–4.83 months), and median OS was 6.90 months (95% CI, 2.63–9.57 months).

Conclusion

Gemcitabine and ipilimumab is a safe and tolerable regimen for PDAC with a similar response rate to gemcitabine alone. As in other immunotherapy trials, responses were relatively durable in this study.

Implications for Practice

Gemcitabine and ipilimumab is a safe and feasible regimen for treating advanced pancreatic cancer. Although one patient in this study had a relatively durable response of nearly 20 months, adding ipilimumab to gemcitabine does not appear to be more effective than gemcitabine alone in advanced pancreatic cancer.
Full-scale observations of dynamic and static axial responses of offshore piles driven in chalk and tills
Authors: Buckley Roisin M. , Jardine Richard J. , Kontoe Stavroula , Barbosa Pedro , Schroeder Felix C.
Published: November 2019

This paper describes and interprets tests on piles driven through glacial tills and chalk at a Baltic Sea windfarm, covering an advance trial campaign and later production piling. The trials involved six instrumented 1·37 m dia. steel open-ended tubes driven in water depths up to 42 m. Three piles were tested statically, with dynamic re-strike tests on paired piles, at 12–15 week ages. Instrumented dynamic driving and re-strike monitoring followed on up to 3·7 m dia. production piles. During driving, the shaft resistances developed at fixed depths below the seabed fell markedly during driving, with particularly sharp reductions occurring in the chalk. Shaft resistances increased markedly after driving and good agreement was seen between long-term capacities interpreted from parallel static and dynamic tests. Analyses employing the sites’ geotechnical profiles show long-term shaft resistances in the chalk that far exceed those indicated by current design recommendations, while newly proposed procedures offer good predictions. The shaft capacities mobilised in the low-plasticity tills also grew significantly over time, within the broad ranges reported for sandy soils. The value of offshore field testing in improving project outcomes and design rules is demonstrated; the approach described may be applied to other difficult seabed conditions.
Developing a hydraulic jump length model on horizontal rough beds
Authors: Yousef F , Mozaffari J , Movahed S
Published: November 2019

Hydraulic jumps play an important role in the dissipation of kinetic energy downstream of hydraulic structures. The roughness of the stilling basin increases energy loss and will affect the hydraulic jump length. In this research, to estimate hydraulic jump length and consider roughness, a semi-analytical equation with unspecified coefficient was developed. Then, 244 sets of laboratory data were used to determine the coefficient of equation. The first series of data was related to a flume with a width of 20 cm and Froude number in the range of 1.1 to 5. The second series of data was obtained from a flume with a width of 50 cm and Froude number in the range of 1.02 to 9.19. USBR data was also used to increase the Froude number range as the third series of data. The results showed that the hydraulic jump length obtained from this model is a function of upstream and downstream depths, upstream Froude number, and bed roughness. It was found that the hydraulic jump length obtained from this model has an error of about 8% in comparison with observational values. In addition, according to the model, increasing roughness will reduce the length of the hydraulic jump.