bluuebunny/crossref_metadata_2025 huggingface dataset:
SIGNO E IDEOLOGIA NA SALA DE AULA: UM ESTUDO DA MEDIAÇÃO PEDAGÓGICA EM UMA ATIVIDADE DE ENSINO NO PRIMEIRO ANO DO ENSINO FUNDAMENTAL
Authors: CORREIA FULCHINI ALZENI DE JESUS , TOSCANO CARLOS
Published: December 2022

O presente trabalho reflete sobre o processo de mediação pedagógica produzido em sala de aula numa atividade de ensino, tendo como referência as tentativas de reinterpretação quanto ao papel da escola na sociedade. Apoiou-se na psicologia histórico cultural ao focalizar a constituição do sujeito, o lugar da linguagem neste processo e como a instituição escolar participa da sua formação, aproximando-se de algumas produções de Vigotski e Luria, dentre outros. O estudo é de tipo qualitativo e interpretativo, incorporando as contribuições da perspectiva enunciativa discursiva, proposta por Bakhtin e Volochínov, na análise da dimensão semiótica do discurso. Os dados analisados se referem a uma atividade em sala de aula ocorrida em uma turma do primeiro ano do ensino fundamental de uma escola pública do interior do Paraná. Ela foi gravada em vídeo e transcrita. A análise dos dados identificou a presença da leitura de uma história pertencente à literatura infantil como disparador da atividade que envolvia leitura, entretanto, a mesma se deu em condições precárias, visto que, como o texto não foi compartilhado, os alunos acompanharam a leitura feita pela professora seguida do destaque das partes componentes de uma árvore. A leitura teve momentos de claro cunho interpretativo e vários signos ideológicos foram apresentados, sem que fossem objetos de consideração, como: a relação egoísta, utilitária e inconsequente do homem com a natureza, além da reafirmação do estereótipo masculino e feminino, que acabaram reforçando modos de ser e estar no mundo e não os problematizando de modo a informar sobre outras possibilidades.
Pengaruh Komunikasi Interpersonal terhadap Kesiapan Mengajar Mahasiswa PLP Prodi Administrasi Perkantoran Universitas Negeri Surabaya
Authors: Damayanti Rima , Puspasari Durinda
Published: December 2022

Tujuan penelitian ini adalah untuk menganalisis pengaruh komunikasi interpersonal terhadap kesiapan mengajar mahasiswa PLP Prodi Pendidikan Administrasi Perkantoran Universitas Negeri Surabaya. Penelitian ini merupakan penelitian kuantitatif. Teknik pengumpulan data yang digunakan adalah angket dan wawancara. Populasi dalam penelitian ini adalah mahasiswa Program Studi Pendidikan Administrasi Perkantoran angkatan 2017 yang sudah melaksanakan kegiatan PLP sebanyak 93 mahasiswa. Sampel dalam penelitian ini menggunakan non-probability sampling dengan bentuk sampling total, dimana jumlah sampel yang digunakan sama dengan jumlah populasi yaitu 93 mahasiswa. Uji coba instrumen dalam penelitian ini terdiri dari uji validitas dan uji reliabilitas. Teknik analisis data yang digunakan dalam penelitian ini yaitu: 1) uji asumsi klasik yang terdiri dari uji normalitas dalam uji heteroskedastisitas; 2) uji hipotesis menggunakan regresi linier sederhana. Hasil penelitian menunjukkan bahwa terdapat pengaruh signifikan komunikasi interpersonal terhadap kesiapan mengajar mahasiswa PLP Prodi Pendidikan Administrasi Perkantoran Universitas Negeri  Surabaya.
Pengaruh Kompetensi Guru dan Fasilitas Belajar terhadap Prestasi Belajar melalui Motivasi Belajar
Authors: Hayati Nur , Pahlevi Triesninda
Published: December 2022

Riset memiliki tujuan untuk dapat mengetahui pengaruh kompetensi guru terhadap prestasi belajar siswa, pengaruh fasilitas belajar siswa terhadap prestasi belajar siswa, pengaruh motivasi belajar terhadap prestasi belajar siswa, pengaruh kompetensi guru terhadap prestasi belajar siswa yang dimediasi oleh motivasi belajar, dan pengaruh fasilitas belajar terhadap prestasi belajar siswa yang dimediasi oleh motivasi belajar. Riset ini dilakukan terhadap siswa SMKN 10 Surabaya jurusan OTKP dengan jumlah 420 siswa. Sampel dalam riset ini berjumlah 205 siswa dengan menggunakan pendekatan probability sampling dengan jenis sampel acak sederhana. Teknik riset ini adalah riset kuantitatif. Data dikumpulkan dengan menggunakan Survei. Kemudian, data dianalisis dengan menggunakan analisis jalur. Hasil dari riset yaitu : 1) kompetensi guru berpengaruh positif dan signifikan terhadap prestasi belajar siswa, 2) fasilitas belajar berpengaruh positif dan signifikan terhadap prestasi belajar siswa, 3) motivasi belajar berpengaruh positif dan signifikan terhadap prestasi belajar siswa, 4) kompetensi guru terhadap prestasi belajar siswa yang dimediasi motivasi belajar tidak berpengaruh signifikan, 5) fasilitas belajar terhadap prestasi belajar siswa yang dimediasi motivasi belajar tidak berpengaruh signifikan.
Inovasi Pelayanan Publik Berbasis E-Government: Studi tentang Pelayanan Akta Kelahiran melalui e-Lampid Kota Surabaya
Authors: Aziz Ronan Agung , Hartono Supri , Puspaningtyas Anggraeny
Published: December 2022

Pemerintah Kota Surabaya melalui Dinas Kependudukan dan Pencatatan Sipil meluncurkan inovasi pelayanan berbasis Eelectronic Government program E-Lampid yaitu untuk mengurus Akta Kelahiran secara online yang bertujuan untuk meningkatkan kualitas pelayanan secara cepat dan mudah.  Dalam penerapan E-Government pada E-Lampid pelayanan akta kelahiran di Kota Surabaya perlu diperhatikan tentang bagaimana elemen sukses penerapan E-Government. Penelitian ini bertujuan untuk menganalisis faktor elemen sukses pada penerapan E-Government pada E-Lampid pelayanan akta kelahiran di Kota Surabaya dan apa saja faktor pendukung dan penghambat dari pelayanan akta kelahiran menggunakan aplikasi E-Lampid. Metode penelitian yang digunakan adalah deskriptif kualitatif dengan teknik pengumpulan data yang dilakukan dengan observasi, wawancara, dan dokumentasi. Adapun yang dijadikan sebagai informan didalam penelitian ini sebanyak 6 orang. Hasil penelitian ini menggunakan teori elemen sukses E-Government (Indrajit, 2006), yaitu: 1). Elemen Support yaitu adanya dukungan pemerintah Kota Surabaya dalam pengembangan inovasi pelayanan berbasis E-Government dan adanya aturan yang mendukung penerapan E-Government. 2). Elemen Capacity yang meliputi Sumber daya finansial berasal dari APBD dan CSR, tersedianya infrastruktur yang mendukung seperti adanya perangkat komputer, printer dan jaringan internet dan infrastruktur sdm yang kompeten melalui pelatihan. 3). Elemen Value yaitu manfaat yang diterima masyarakat adanya penerapan E-Government yakni kemudahan mendapatkan pelayanan tanpa perlu datang ke kantor dinas maupun kekelurahan dan proses permohonan yang cepat terselesaikan.
Making Suggestions while Collaborating in L1 English: Common Structures and Strategies
Authors: Edstrom Anne
Published: December 2022

The present study examines English suggestions that surfaced naturally during a collaborative writing task in a Spanish class. Students’ limited L2 (second language) oral skills made it necessary for them to speak in their L1 (first language), English, while creating a written product in Spanish. Given the interactive nature of the assignment, making suggestions was a collaborative gesture; to remain silent was to be off-task, uncooperative, or uncommitted to the group’s success. This article explores the syntactic structures, pragmatic strategies, and redressive actions used by native speakers of American English when making suggestions. The data indicate that participants made frequent use of modals and did not use the more formulaic strategies included in some lists and taxonomies (Koike 1994; Martínez-Flor 2005)
Decalibrating the Language. J. H. Prynne’s Biting the Air
Authors: Wit Pietrzak
Published: December 2022

The article focuses on J.H. Prynne’s 2003 volume Biting the Air. I seek to explore the modes of reconstitution of language that Prynne shows to be enslaved in the various discourses of modernity. The idea of enslaving discourse is shown to be an unacknowledged aspect of modernity on the basis of Don DeLillo’s Cosmopolis and Zbigniew Herbert’s “Report from the Besieged City”, both of which may be seen as illustrations of the hegemony of linguistic enslavement that Prynne struggles against in his poetry. Despite the difference of socio-linguistic and temporal context, both DeLillo and Herbert show that language, as Prynne implies in the ending of Biting the Air, is a “calibrated” mechanism of oppression that, unbeknownst to most people, keeps man fixed within the field of binary rhetoric. In response to that situation, Prynne’s poem is demonstrated to refashion the idiom by emphasizing the multiple process of meaning creation. It is in such decalibration of language that a path may be located beyond the reified linguistic praxis.
Paraoxonase 1 (PON1) gene Q192R polymorphism in patients with vitiligo
Authors: Akcilar Raziye , Namdar Nazli Dizen
Published: December 2022

Background/Aim: Vitiligo is a prevalent inflammatory illness that can affect the skin and mucosal surfaces and is characterized by patchy loss of skin pigmentation. Paraoxonase1 (PON1) is an esterase enzyme with antioxidant properties that binds to high-density lipoproteins. We examined whether the PON1 gene Q192R polymorphism is a risk factor for vitiligo among Turkish people.

Methods: The study included 70 controls and 60 vitiligo cases. Polymerase chain reaction and the restriction fragment length polymorphism technique were used to genotype the PON1 gene Q192R polymorphism.

Results: PON1 gene Q192R genotype distribution was 66.7% QQ, 33.3% QR, and 0% RR in the vitiligo and 81.4% QQ, 18.6% QR, and 0% RR in the control (P = 0.05). When vitiligo patients were compared with controls, the prevalence of the PON1 QR genotype was substantially higher and was linked to a 2.19-fold greater risk of developing vitiligo (odds ratio: 2.19, 95% confidence interval (CI): 0.97–4.91).

Conclusion: These findings imply that Q192R polymorphisms in the PON-1 gene may be linked to vitiligo in the Turkish population. The PON1 QR genotype may be a major genetic risk factor for vitiligo susceptibility and progression. Further studies with larger populations should more thoroughly clarify the association.
Gídeo véio vive em nós! Experiências coletivas na revitalização de um museu quilombola no Rio Grande do Norte
Authors: Ferreira Flávio Rodrigo Freire , Bezerra Nilton Xavier
Published: December 2022

A luta de comunidades quilombolas inclui a defesa de seus valores e tradições culturais. As lideranças quilombolas da serra da Gameleira (São Tomé - RN) têm buscado construir espaços que permitam uma divulgação e valorização da cultura local. Com efeito, o objetivo deste artigo é apresentar resultados do projeto: Museologia Social e instalação do museu comunitário quilombola - Gideo Véio. A pesquisa foi motivada a partir de ações patrimoniais desenvolvidas por uma liderança quilombola. Apresentamos assim, os resultados de projeto realizado durante o ano de 2021. Escolhemos como referencial teórico-metodológico a museologia social (CHAGAS, 2018), cujas lentes permitiram executar três ações principais: desenvolvimento de processo de sensibilização comunitária sobre o equipamento museu; realização de pesquisa mediante inventário coletivo; e montagem e lançamento da exposição “Gídeo véio vive em nós”. Assim, pensamos que o museu quilombola e sua primeira exposição, reúne e protege bens patrimoniais, lugares simbólicos e elementos da memória coletiva da comunidade, a fim de garantir o direito à cidadania patrimonial (LIMA FILHO, 2015).
O outro em narrativas sobre a Coleção Perseverança
Authors: Marcante Maicon Fernando
Published: December 2022

A Coleção Perseverança é composta por objetos sagrados provenientes dos terreiros alagoanos que foram atacados no violento episódio conhecido como Quebra de Xangô, ocorrido em 1912. Naquele momento, as peças foram caracterizadas pela imprensa favorável ao Quebra como evidências de supostas práticas de feitiçaria, a partir de uma infinidade de (des)qualificativos racistas e pejorativos. Menos de 40 anos depois, as mesmas peças foram incorporadas ao Instituto Histórico e Geográfico de Alagoas e valoradas como possivelmente uma das mais preciosas coleções de objetos religiosos afro-brasileiros. Que processos implicaram tal ressignificação? Trata-se de uma ruptura efetiva ou continuidades podem ser identificadas? Almejando lançar luz sobre estas inquietações, assumo que os objetos refletem não apenas o passado do qual foram arrancados, mas também os processos posteriores que os constituíram enquanto coleção museal.
Entre passado e futuro: o novo Estatuto Social e o programa de "histórias" do Museu de Arte de São Paulo
Authors: Fabris Yasmin , De Oliveira Corrêa Ronaldo
Published: December 2022

Este artigo tem como objetivo refletir sobre as mudanças no posicionamento conceitual do Museu de Arte de São Paulo (MASP), entre os anos 2014 e 2016, especificamente a partir das alterações na estrutura de gestão da instituição, reformulação do Estatuto Social e da proposição de um programa anual temático que orienta as atividades da entidade. O método empregado para o desenvolvimento deste estudo foi documental, com a revisão de exemplares alocados no Centro de Pesquisas e Documentação do MASP. A análise buscou articular a documentação com o cronograma expositivo do Museu no período selecionado. Pretende-se, a partir dessa articulação, demonstrar como as iniciativas encampadas pelo MASP a partir de 2014 se associa com discussões teórico-conceituais no campo dos museus e das ciências sociais e, também, vinculam as ações da atual Direção Artística com as propostas programáticas encampadas no período de fundação da entidade.
IV Bienal do Sertão: arte e curadoria fora do eixo
Authors: Lima de Melo Renata Fernanda
Published: December 2022

Este artigo faz uma análise da narrativa curatorial da IV Bienal do Sertão de Artes Visuais, realizada em 2019 e investiga  a partir do conceito de “invenção do Nordeste” as relações deste evento artístico fora do eixo hegemônico com temas como história das exposições, memória/poder e identidade  e como as categorias Nordeste e Sertão são mobilizados pelo discurso curatorial e pelas poéticas artísticas. Ao considerar exposições como dispositivos políticos, o artigo busca  questionar  qual (is)  imagens do Nordeste/Sertão se  propagam  dentro de espaços de Arte Contemporânea, especificamente na IV Bienal do Sertão de Artes Visuais e  como as poéticas de alguns dos artistas participantes desta edição da Bienal dialogam com estas questões.
The Fundamentals of Financial Mathematics for Actuaries
Authors: Falin Gennady
Published: December 2022

The book covers the most important parts of the syllabus for the actuarial qualification examination in financial mathematics of The Institute and Faculty of Actuaries (UK) and that of The Central Bank of Russian Federation. Basic concepts are illustrated by actual financial products. Each chapter is concluded with a set of problems from the past actuarial exams CT1 and CM1A of The Institute and Faculty of Actuaries, all with detailed solutions. According to the new Curriculum 2022 of the Institute and Facilty of Actuaries, particular attention is paid to the use of Microsoft Excel for solving problems in financial mathematics. The book is intended for students of mathematics, economics and finance who wish to become a qualified actuary. The book can also be used as a basis for an introductory one-year course in financial mathematics.
Probability theory and mathematical statistics course for geology students:
Authors: Ponomarenko Lyubov
Published: December 2022

The author of this textbook has a vast experience of teaching probability theory and mathematical statistics to the students of the Faculty of Geology at the Lomonosov Moscow State University both as a senior lecturer and a practice class professor. The textbook combines simple presentation with clearly formulated definitions and theorems. The author provides a lot of case studies explaining the main concepts and theorems. Emphasis is placed on application of theoretical knowledge to problem solving. Each chapter contains revision questions and provides practical tasks on the topic. Problems are presented with answers, and some of them with short solutions. This textbook will also be useful to students of other natural science faculties studying the basic course of probability theory and mathematical statistics of one-two semester duration.
Improved Mediolateral Gap Balance Achievement with Instrumented Navigated Total Knee Arthroplasty Compared to Conventional Instrumentation
Authors: Angibaud Laurent , Fan Wen , Kerveillant Florian , Dubard Philippe , Torrollion Marine , Rueff Matthew , Sah Alexander , Huddleston James
Published: December 2022

Total knee replacement (TKA) represents a well-established reconstructive procedure for end-stage knee joint disorders with the balancing of soft-tissue envelope throughout the full arc of motion as a newly emerging possibility. This cadaveric study evaluated the ability to achieve targeted mediolateral (ML) gap balance throughout the arc of motion using conventional mechanical instrumentation versus a computer-assisted orthopaedic surgery (CAOS) system featuring an intraarticular distractor while considering surgeon experience level. For the CAOS system, an intraarticular distractor applied a quasi- constant distraction force to the joint (instrumented) while the conventional system involved conventional spacers. Regardless of experience level, the instrumented TKAs were associated with a significantly lower ML gap differential than the conventional TKAs. In contrast, regardless of the type of instrumentation, there were no significant differences between the junior and senior surgeon mean gaps. Historically, soft tissue balancing during TKA has been reported as an art rather than a science. In this regard, the addition of dedicated technology to characterize the soft-tissue envelope during TKA has the potential to provide an augmented perspective to the surgeon and can be particularly beneficial for junior surgeons. The present study established that the usage of instrumented CAOS led to significantly lower ML gap differences than conventional instrumentation.
Towards Automatic Generation of Patient-Specific Knee Models
Authors: Elyasi Elaheh , Bucki Marek , Asaadi Boubaker , Elizondo Daniel , Perrier Antoine
Published: December 2022

The objective of the current paper is to present a pipeline designed to reduce the pre-processing time required to build subject-specific finite element knee models and facilitate their clinical integration. The pipeline involves development and validation of an atlas model of the knee joint and features of the TwInsight software suit that use novel methodologies such as: 1) deep learning for automatic segmentation of the bones from computed tomography scans, 2) automatic generation of finite element meshes with hexahedral elements, and 3) anatomical inference algorithm to adapt the atlas model to the morphology of a subject and result in the subject’s personalized biomechanical model.
Automated analysis of morpho-functional interbone parameters of the knee based on three dimensional (3D) surface data
Authors: Grothues Sonja , Berger Luisa , Radermacher Klaus
Published: December 2022

Interbone parameters of the knee are of relevance in clinical practice, e.g. for the assessment of the functional anatomy of the individual patient. However, respective landmark identification and parameter derivation is mostly done manually. An automated analysis could enable the processing of large datasets, which could again enable the derivation of reference ranges or safe zones for various populations. Hence, the aim of this study was to automate the derivation of interbone parameters from 3D surface data of the knee and to evaluate the method’s robustness against a large dataset.

A dataset of 414 knees from patients scheduled for total knee arthroplasty (TKA) was available for the analysis. For each case, knee surface models derived from CT as well as coordinates of the hip and ankle joint centers were available. Eight interbone parameters of the knee were identified in a literature research and an existing framework for morphological analysis of the knee was extended, in order to automatically calculate those parameters.

The interbone analysis succeeded for 405 (97.8%) cases. After the exclusion of implausible cases, 373 (90.1%) parameter sets remained for statistical analysis.

Differences in methodology, populations, imaging technique etc. complicate the comparison with values from the literature. However, for similar studies a good agreement in parameter values was found.

The workflow presented proved robust against a large dataset of knee surface models. In the future, information about the bones’ relative position in the active, weight-bearing situation should be incorporated, in order to assess the impact on knee interbone parameters.
Comparison of a Novel Joint Distraction Radiology Protocol in Total Knee Arthroplasty Planning with Navigated Joint Gaps
Authors: Liu David , Jagota Ishaan , Twiggs Joshua , Miles Brad
Published: December 2022

Native extension and flexion joint gaps are primarily measured intraoperatively using devices such as navigation systems or tensioners, but there are advantages to being able to pre-operatively plan to such gaps. This study aims to validate the ability of a novel distracted joint gap radiology protocol to measure pre-operative extension and

flexion joint gaps. A retrospective study comprised of 42 knees was performed. Patient imaging was obtained and used to perform segmentation, landmarking and 3D-to-2D registration. The pre-operative medial and lateral joint gaps were determined in extension and flexion. Intraoperatively, a range of motion analysis was conducted using the Brainlab Knee 3 navigation system to measure the joint gaps in extension and flexion.

In extension, both medial and lateral pre-operative radiological and intraoperative navigated gaps displayed moderate and statistically significant correlations (r=0.45; p=0.003 for medial and r=0.4; p=0.01 for lateral). In flexion, only the medial radiological and navigated joint gaps correlated (r=0.54, p<0.001), with a not statistically significant trend for the lateral flexion joint gaps.

The moderate and statistically significant correlations between these joint gaps to those measured intraoperatively suggests they are reflective of on the table experience with patients. Although further work is required to understand if differences are attributable to variability in the radiological or intra-operative assessments, the pre- operative analysis technique described in this study provides the opportunity to develop a more holistic pre-operative surgical plan which considers the state of both hard and soft tissue within the joint.
ARCH-COMP22 Category Report: Continuous and Hybrid Systems with Linear Continuous Dynamics
Authors: Althoff Matthias , Forets Marcelo , Schilling Christian , Wetzlinger Mark
Published: December 2022

We present the results of the ARCH1 2022 friendly competition for formal verification of continuous and hybrid systems with linear continuous dynamics. In its sixth edition, two tools have been applied to solve nine different benchmark problems in the category for linear continuous dynamics (in alphabetical order): CORA and JuliaReach. This report is a snapshot of the current landscape of tools and the types of benchmarks they are particularly suited for. Due to the diversity of problems, we are not ranking tools, yet the presented results provide one of the most complete assessments of tools for the safety verification of continuous and hybrid systems with linear continuous dynamics up to this date.
Validation of a Patient Outcome Prediction Tool Relative to Surgeon Predictions of Patient Outcome in Total Knee Arthroplasty
Authors: Roe Justin , Parker David , Liu David , Fritsch Brett , Baker Matthew , Jagota Ishaan , Twiggs Joshua , Miles Brad
Published: December 2022

A key goal of all TKA alignment strategies is to achieve joint balance. This study aims to compare the alignments achieved by preoperatively planning to a novel distracted joint gap protocol to common alignment strategies as well as to the alignment of a healthy non-arthritic population.

A retrospective study comprised of 145 knees was performed. A long-leg supine CT scan, weightbearing AP knee X-ray and two distracted knee X-rays (one each in extension and flexion, making use of an ankle weight to open the joint) were taken pre-operatively. This imaging was used to perform segmentation, landmarking and 3D-to-2D registration. The medial and lateral joint gaps were determined in extension and flexion.

The mean weightbearing, KA planned and distracted joint planned HKA were 4.7° (±5.9°) varus, 0.3° (±3.2°) varus, and 2.2° (±3.5°) varus. This compares to a healthy adult HKA of 1.3° (±2.3°) varus. A patient level comparison between the planned KA and distracted joint HKA found that the coronal angles of the two alignments are within 3° of each other for 64% patients, within 3-5° for 26% of patients and greater than 5° for the remaining 10% of patients.

Of those compared, the planned distracted HKA was the closest to the constitutional varus HKA of a healthy population. Patient level analysis highlighted the fundamental differences between the planned KA and joint distracted alignments. By considering both hard and soft tissue, the planned joint distracted alignment allows for a more holistic foundation for pre-operative surgical planning for a given patient.
Standardized Evaluation of Current Ultrasound Bone Segmentation Algorithms on Multiple Datasets
Authors: Pandey Prashant , Hohlmann Benjamin , Brößner Peter , Hacihaliloglu Ilker , Barr Keiran , Ungi Tamas , Zettinig Oliver , Prevost Raphael , Dardenne Guillaume , Fanti Zian , Wein Wolfgang , Stindel Eric , Cosio Fernando Arambula , Guy Pierre , Fichtinger Gabor , Radermacher Klaus , Hodgson Antony J.
Published: December 2022

Ultrasound (US) bone segmentation is an important component of US-guided or- thopaedic procedures. While there are many published segmentation techniques, there is no direct way to compare their performance. We present a solution to this, by curating a multi-institutional set of US images and corresponding segmentations, and systematically evaluating six previously-published bone segmentation algorithms using consistent metric definitions. We find that learning-based segmentation methods outperform traditional al- gorithms that rely on hand-crafted image features, as measured by their Dice scores, RMS distance errors and segmentation success rates. However, there is no single best performing algorithm across the datasets, emphasizing the need for carefully evaluating techniques on large, heterogenous datasets. The datasets and evaluation framework described can be used to accelerate development of new segmentation algorithms.
Automatic Friedman’s Axis placement via the use of deep learning algorithms
Authors: Daviller Clément , Polakovic Sandrine V. , Greene Alexander T. , Bertrand Fabrice
Published: December 2022

Reference axis based on Friedman’s approach is widely recognized as an anatomic landmark from which to measure and compare implant parameters within preoperative planning software for total shoulder arthroplasty. Equinoxe Planning Application (ExactechInc.) offers 3D measurements techniques for glenoid version and inclination requiring meticulous placement of trigonum and glenoid center. We propose as automatic determination of this reference axis, based on deep learning that shown a median error of less than 1°.
Benchmarks for the Formal Verification of Power Systems
Authors: Althoff Matthias
Published: December 2022

Benchmark proposal: Safe renewable energy systems are becoming increasingly impor- tant to combat climate change. Electric utility companies often use conservative approaches to feed in renewable energy to ensure a safe operation due to a lack of advanced analysis techniques. So far, mostly simulations are used in practice to safeguard the system against certain contingencies, which cannot provide guaranties. While so-called direct methods based on Lyapunov functions potentially provide formal guarantees, they are not really used in practice due to the difficulty of finding Lyapunov functions of larger models. How- ever, we believe that reachability analysis can be conveniently used to ensure correctness, because it can be performed automatically without expert knowledge. To analyze the state of the art in this important application area, we provide a tool that automatically gener- ates benchmark problems from a given system description. We also provide problems of different difficulty and for different types of analysis, namely transient stability analysis, verifying regions of attraction, and verifying robustness against uncertain power demand and production. Exemplary solutions of benchmark problems are shown as well.
Does augmented reality improve clinical outcome in TKA? A prospective observational report.
Authors: Van Overschelde Philippe , Vansintjan Pieter , Byn Pieter , Lapierre Cynthia , Van Lysebettens Wouter
Published: December 2022

AIMS: The Pixee Knee+ system offers intraoperative assistance through augmented reality glasses. This allows the surgeon to see the tibial and femoral axis depicted on the surgical field, providing real-time information during surgery.

METHODS: 122 patients received TKA surgery with the Pixee Knee+ system, and were matched based on gender and age to 122 patients who received conventional surgery. PROMs (Oxford knee Score, KOOS, and Forgotten Joint score) were collected preoperatively, at 6 weeks and 3 months. The difference between the scores at 6 weeks versus preoperative (Delta) was analyzed over time of surgery, in order to evaluate any possible surgeon learning curve.

RESULTS: Pixee patients scored significantly lower on the symptoms sub-scale of the KOOS score at 6 weeks. Similarly, at 3 months, the Quality of life sub-score, Forgotten Joint score and Oxford Knee Score were all significantly worse for the Pixee group. When analyzing the Delta KOOS over time, a clear increase in the linear model could be established for the Pixee group, whereas the Delta KOOS outcomes in the conventional group remained at a plateau.

CONCLUSION: The use of the Pixee Knee+ system results in an initial inferior clinical outcome when comparing the average of the two groups. This is likely explained by a learning curve, which shows an increase over time of the Delta KOOS at 6 weeks in the Pixee group. To what extent this increase over time will persist remains to be investigated
Aproximaciones a la realidad de los y las periodistas de la zona centro de Ecuador en época de pandemía
Authors: Alvarez Lorena , Aguilar Alejandrina , Guadarrama Jorge
Published: December 2022

La presente investigación se realizó en la zona Centro del Ecuador en las provincias de Cotopaxi, Tungurahua, Bolívar y Chimborazo con el objetivo de conocer de primera mano cuál fue la situación que tuvieron que enfrentar durante la Pandemia, bajo la consideración que la mayoría trabaja en medios pequeños y la realidad del periodista de provincia dista mucho del periodista de los grandes medios de comunicación en las grandes ciudades. Se realizaron encuestas y entrevistas especializadas y fichas de observación. Entre los principales hallazgos están que durante la Pandemia, se dio un salto de lo tradicional a lo digital en medio de procesos apresurados, además mostraron confusión por protocolos de bioseguridad que en algunos casos no están del todo claros, la mayoría coincide en que se visibilizó y agudizó la precarización laboral manifiesta a través del incremento significativo de trabajo y riesgo laboral, se mencionaron además cambios en el proceso de cobertura  así como la dificultad para llegar a las fuentes, aunque además señalan que una de las circunstancias que más se rescata es la solidaridad entre periodistas. La investigación es una aproximación debido a la situación de la pandemia.
Realismo integral
Authors: Ramírez Mario-Teodoro
Published: December 2022

Dentro de las diversas posturas sobre el realismo en la discusión filosófica actual, propongo aquí lo que llamo realismo integral, como una alternativa que pueda incorporar la dimensión o el problema de la subjetividad en una teoría realista general. Asumida la crítica al subjetivismo (y subjetualismo) de la filosofía moderna y posmoderna hecha por el realismo especulativo, particularmente por Quentin Meillassoux, considero que, no obstante, es necesario distinguir todavía entre una teoría de la experiencia —perceptiva, científica, histórica—, que puede sostener tesis correlacionistas, y esta misma experiencia en su realidad efectiva, pensada de acuerdo con los principios de un filosofar realista. Como consecuencia de esta perspectiva, ofrezco brevemente una reconstrucción en clave realista de los tres momentos del proceso de la subjetivación.
Mode of Actions of Bile Acids in Avoidance of Colorectal Cancer Development; and their Therapeutic Applications in Cancers - A Narrative Review
Authors: Kaur Kulvinder Kochar , K. Allahbadia Gautam Nand , Singh Mandeep
Published: December 2022

Bile Acids (BAs) possess a considerably significant part in the form of emulsifiers in digestion besides absorption of dietary lipids. BAs represent amphiphilic molecules, that are primary metabolites formed from cholesterol by the aid of enzymes acting on cholesterol. Earlier BAs were believed to be tumor repressors. The tumor repressive actions of BAs are correlated with programmed cell death (PCD). Furthermore, dependent on this observation different Synthetic BAs products have been generated along with their utilization regarding induction of PCD (in the form of apoptosis, autophagy or necroptosis in variable kinds of human cancers. Thus we conducted a narrative review till August 2022. The present article might form the basis of generationof such innovative therapies even for cancers/tumors that are cisplatin resistant. With time these therapies might be used for the treatment of neurodegenerative diseases (NDD), amyotrophic sclerosis, and numerous metabolic and haematological diseases as described for use of TUDCA.
Antiviral Effects and Mechanisms of Action of Water Extracts and Polysaccharides of Microalgae and Cyanobacteria
Authors: Besednova Natalya N. , Andryukov Boris G. , Kuznetsova Tatyana A. , Zaporozhets Tatyana S. , Kryzhanovsky Sergey P. , Ermakova Svetlana P. , Shchelkanov Mikhail Yu.
Published: December 2022

Microalgae (MA) and cyanobacteria (CB) are currently attracting much attention from scientists due to the high biological activity of many secondary metabolites of these aquatic organisms. This review presents up-to-date modern data on the prospects for using polysaccharides (PS) of these marine aquatic organisms as effective and practically safe antiviral agents. These natural biopolymers are polyvalent compounds, which allows them to bind to several complementary biological target receptors. Particular emphasis is placed on the exopolysaccharides (EPS) Spirulina sp. (Arthrospira sp.), Porphyridium sp., Chlorella sp., and Euglena sp., whose antiviral activity makes them promising for the creation of drugs, biologically active food supplements, and products for functional nutrition. The mechanisms of the biological action of PS and the targets of these compounds are presented with a brief description of PS's anti-inflammatory, immunomodulatory and antioxidant actions, which make the most significant contribution to the antiviral effects. The authors hope to draw the attention of researchers to the use of water extracts and polysaccharides of microalgae and cyanobacteria as potential broad-spectrum antiviral agents that can become the basis for new antivirus strategies.
Persistence, Clinical and Economic Impact of Infliximab CT-P13 in Rheumatoid Arthritis, Psoriatic Arthropathy and Ankylosing Spondylitis Naïve and Switched Patients: After 5 Years of Follow-Up
Authors: Borrás-Blasco Joaquín , Valcuende-Rosique Alejandro , Rosique-Robles Dolores , Casterá Elvira
Published: December 2022

Objective: Study the economic impact and persistence of Inflectra® in rheumatoid arthritis (RA), psoriatic arthropathy (PSA), psoriasis, ankylosing spondylitis (AS) naïve, and Remicade® switched patients.

Methods: Retrospective observational cohort study of patients treated with Inflectra® for more than six months in a five years analysis. We collected age, sex, indication, dose, and persistence (in years) for Inflectra® naïve and Remicade® switched patients. Efficacy endpoints included a disease activity score calculator for rheumatoid arthritis (DAS28) and bath ankylosing spondylitis disease activity index (BASDAI). Safety was also assessed. We determined each patient's actual cost of Inflectra® treatment from individualized IV administration and correlated dates during the study period. We simulated the actual cost of these patients if the patients received Remicade®.

Results: During five years, 62 patients (38 women; 31 AS, 18 RA, 13 PSA were treated with Inflectra®. 33 (53%) patients were naïve patients, and 29 (47%) were Remicade® switched patients. In Sept 2019, 33 patients continued on Inflectra® treatment (11 naïve; 22 Remicade® switched) in clinical remission. Twenty-nine patients discontinued therapy, 24 due to relapse, and five due to adverse reactions. All patients with Inflectra® presented a persistence of 24.4±7.4 months. The persistence in naïve patients was 19.1±4.4 months and in Remicade® switched patients was 29.7±5.8 months. The total associated costs of the Inflectra® treatment throughout the observation period were 901.840€. If these patients had been treated with Remicade®, the total cost of therapy would have been 1.099.803€. The use of Inflectra® saved 197,964€ during five years.

Conclusions: Inflectra® produces similar persistence and substantial cost savings when used in Infliximab naïve patients and Remicade® switched patients.
Diagnosis dan terapi patent ductus arteriosus pada anjing
Authors: Widjanarko Christophorus Algriawan Bayu , Prasetya Titus Ardhi
Published: December 2022

Patent Ductus Arteriosus (PDA) adalah penyakit jantung kongenital yang disebabkan oleh gagal menutupnya ductus arteriosus dan menyebabkan abnormalitas aliran darah dari aorta menuju arteri pulmonalis. Kondisi tersebut mengakibatkan berlebihnya volume darah dalam sirkulasi paru-paru, atrium kiri, dan ventrikel kiri yang dapat berkontribusi pada terjadinya gagal jantung kongestif. Tulisan ini melaporkan seekor anjing Toy Poodle jantan berusia 7 bulan dibawa pemiliknya untuk pemeriksaan kesehatan dan vaksinasi. Pemilik anjing menyatakan pasien tidak memiliki keluhan sakit maupun riwayat penyakit. Hasil auskultasi terdengar suara jantung continuous murmur grade V/VI di basal jantung kiri. Hasil pencitraan echocardiography memperlihatkan dilatasi pada arteri pulmonalis disertai aliran darah turbulen dan terdeteksi keberadaan ductus arteriosus. Pasien juga mengalami overload volume darah pada atrium kiri. Ductus arteriosus pasien kemudian ditutup secara operasi dengan metode ligasi intrapericardial. Pemeriksaan echocardiography pada 48 jam pasca operasi menunjukan adanya aliran residual pada arteri pulmonalis. Ukuran atrium kiri kembali ke rentang normal dan grade continuous murmur turun ke II/VI. Aliran residual pada pasien masih terdeteksi hingga satu bulan pasca operasi, namun suara murmur sudah tidak terdengar dan ukuran ruang-ruang jantung tetap berada dalam rentang normal. Ligasi pada PDA masih menyisakan aliran residual pada arteri pulmonalis dan pemantauan terhadap potensi residual permanen dan rekanalisasi terus dilakukan pada pasien.
Penanganan skabies pada kucing di Yourdaily Petshop and Vet Jakarta Timur
Authors: Dewi Alissa Hadi Kusuma , Prihastuti Ajeng Erika , Wisesa Ida Bagus Gede Rama , Adrenaline Sruti Listra
Published: December 2022

Skabies merupakan penyakit sistem integumen pada kucing yang disebabkan oleh tungau Sarcoptes scabiei maupun Noroedres cati. Tungau masuk jaringan kulit dengan menembus lapisan epidermis, kemudian membuat terowongan sebagai tempat untuk bersarang dan bertelur. Aktivitas mekanis dan enzimatis tungau didalam lapisan epidermis menimbulkan reaksi alergi dan gejala klinis berupa pruritus, alopesia, papula, hyperkeratosis dan krusta pada hewan. Studi kasus ini melaporkan tampilan gejala klinis, pemeriksaan penunjang dan penanganan kasus skabies pada kucing bernama Chelsea ras Persia berumur 7 tahun. Kucing dibawa pemiliknya ke klinik hewan karena ada keropeng pada telingan. Pemeriksaan fisik dilakukan dan diagnosa penunjang berupa skin scraping pada superfisial pinna telinga. Hasil pemeriksaan skin scraping ditemukan infestasi tungau Notoedres cati pada kucing. Penanganan yang diberikan berupa injeksi antiparasit ivermectin, antihistamin diphenhydramine, dan kucing dimandikan dengan sampo lime sulfur 2%. Pemilik kucing Chelsea diminta kembali datang ke klinik pada hari ke 14 pasca terapi untuk melakukan kontrol dan hasilnya sudah tidak ditemukan infestasi tungau. Injeksi ivermectin kedua tetap diberikan untuk memastikan tungau telah tereliminasi secara keseluruhan.
Diagnosis Haemobartonella felis subklinis pada kucing
Authors: Putra Hamdika Yendri , Maulana Naufal Hadam , Bahtiar Noor Ihsan Anzary , Pratiwi Puteri , Aziz Hakim , Vadya Dieniza , Mayori Geovany
Published: December 2022

Ektoparasit yang teridentifikasi pada satu hewan kesayangan berkorelasi pada infestasi endoparasit, salah satu contoh endoparasit yang menyerang hewan peliharaan adalah Haemobartonella felis. Kucing sebanyak 7 ekor dari pemilik yang sama dibawa ke klinik hewan. Pemilik mengeluhkan seekor kucing memiliki suhu tubuh yang selalu tinggi saat diukur. Kucing yang lain tidak memiliki keluhan dan gejala serupa, namun pemilik ingin dilakukan pemeriksaan umum pada semua kucingnya. Hasil pemeriksaan klinis tidak ditemukan infestasi ektoparasit, suhu tubuh kucing berkisar 39,8-40,0 °C dengan bobot badan 2-4 kg dan berusia antara 5-24 bulan. Pemeriksaan lanjutan yang dilakukan adalah pemeriksaan hematologi dengan metode complete blood count (CBC) mengunakan alat hematology analyzer dan blood smear inspection. Pemeriksaan ulas darah 4 dari 7 kucing menunjukkan hasil positif adanya parasit pada badan sel darah merah. Pemilik diberikan resep berupa antibiotik doxycicline dengan dosis 5 mg/Kg BB untuk diberikan kepada kucingnya 2 kali sehari selama 28 hari.
Sosialisasi Pemanfaatan Metode Tabulampot sebagai Alternatif Dalam Meningkatkan Produktivitas Lahan Pekarangan di Desa Gelangsar, Kabupaten Lombok Barat
Authors: Farista Baiq , Virgota Arben , Suripto  , Jupri Ahmad , Julisaniah Nur Indah , Candri Dining Aidil
Published: December 2022

Gelangsar Village, West Lombok Regency has a hilly topography and steep slopes. This condition causes low soil fertility in several locations, especially locations with steep slopes. The hills around the village of Gelangsar also affect the incoming light intensity. Resident around the hillsides, complained that the fruit trees in their yards could not bear fruit even though they were more than 10 years old. The solution offered to overcome these problems is the application of the tabulampot method. This program aims to introduce and apply the tabulampot method in the yard. The Tabulampot method is expected to provide maximum fruit crop yields. The method used in this program is socialization and tabulampot pilot project. The socialization method used was counseling and distribution of leaflets (brochures), while the application of tabulampot was carried out through the establishment of a pilot project. This program has been successfully. The participants actively asked questions in discussion sessions and also in the practice of making tabulampot. Tabulampot has a great opportunity to be implemented in the Gelangsar Village because it is easy and cheap.
Corporate Farming as an Effort to Increase Rice Farming Production in Central Java
Authors: Iskandar Muhammad Joni , Prasetyowati Rini Endang , Ningsih Dwi Haryati
Published: December 2022

This study aims to estimate production factors and technical efficiency of rice farming using the corporate farming model. The research location was determined purposively in Sukoharjo Regency, Central Java. The research sample is 51 corporate farmers determined by census. The analytical method uses the stochastic frontier 4.1.C computational program with the Maximum Likelihood Estimation (MLE) method. The estimation results show that the factors that influence rice production are land area, Urea fertilizer and NPK fertilizer. While the value of the technical efficiency of rice farming in the corporate farming model is 0.75 (75%). Farmers still have the opportunity to increase their efficiency by 25%.
Bioprospection of Potential Medicinal Plant Diversity in the Wana Lestari Community Forest, Karang Sidemen Village
Authors: Valentino Niechi , Latifah Sitti , Hadi Muhammad Anwar
Published: December 2022

Medicinal potential plants that are scattered in community forest areas have opportunities that can be utilized in ecosystem-based sustainable forest management. Considering the potential medicinal plants have played a major role in maintaining the health condition of the community around the forest from generation to generation. This study aims to determine the abundance of medicinal plant species in the Wana Lestari Community Forest, Karang Sidemen Village based on the value of the Ecological Index. The research method used is Stratified Random Sampling with Replacement with a total of 59 research sample plots. The results showed that the types of medicinal plants at the level of trees, poles, saplings, seedlings, shrubs, bush, terna, lianas, and ferns which had the highest Importance Value Index (IVI) were D. zibethinus (72.42%) trees level, D. zibethinus (111.82%) poles level, C. canephora (144.98%) saplings level, C. canephora (109.64%) seedlings level, C. frutescens L (70.33%) shrubs level, H. capitata Jacq. (103.07%) bushs level, C. prostrata (26.69%) ternas level, M. cordata (92.46%) lianas level, and D. esculentum (169.39%) ferns level. The Morishita index shows that most species at the trees, shrubs, bushes, ternas, lianas, and ferns levels spread in groups while most of the plant species at the pole, sapling, and seedling levels spread randomly. In addition, the Species Diversity Index (H') of medicinal plants showed values ​​at the level of trees (2.08), poles (1.92), saplings (1.16), seedlings (1.72), shrubs (1.8), bushs (1.79), ternas (2.94), lianas (1.44) and ferns (0.53). Furthermore, the value of the species richness index (R1) of plants with medicinal potential is at the level of the tree (2.68), poles (2.82), saplings (1.93), seedlings (1.72), shrubs (1.84), bushs (2.22), ternas (4.17), lianas (1.87) and ferns (0.38). The evenness index value (E') of medicinal potential plants is at the level of trees (0.73), poles (0.75), saplings (0.48), seedlings (0.61), shrubs (0.92), bushs (0.7), ternas (0.82), lianas (0.58) and ferns (0.49).
In Vitro Effectiveness Test of Sagoo Cortex Liquid Smoke to Inhibit the Growth of Ganoderma orbiforme (Fr.) Ryvarden
Authors: Yusmar M , Surwadinata Antama , Tasla Irwan , Oksana Oksana , Zam Syukria Ikhsan
Published: December 2022

Ganoderma orbiforme is a pathogenic fungus that cause basal stem rot especially in oil palm, so it needs to be controlled. One of the alternative controls used is liquid smoke. This research aims to examine several concentrations of sagoo cortex liquid smoke to inhibit the growth of G. orbiforme in vitro. This research was conducted in October untill Desember 2021 at the Pathology, Entomology, Microbiology and Soil Science Laboratory, Faculty of Agriculture and Animal Science, Islamic State University Sultan Syarif Kasim Riau. Research was test of 6 concentrations of sagoo cortex liquid smoke (0, 1, 2, 3, 4, and 5%) with 4 replications. Liquid smoke had a total phenol ± 7.44%. Sagoo cortex liquid smoke with 1% concentration has already very effective to inhibit in the macroscopic, microscopic, growth rate, wet mass and dry mass